LOCUS       DAMJYN010000001       131326 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.001, whole genome shotgun sequence.
ACCESSION   DAMJYN010000001 DAMJYN010000000
VERSION     DAMJYN010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 131326)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 131326)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..131326
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.001"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            35..664
                     /locus_tag="PC466_000001"
     CDS             35..664
                     /locus_tag="PC466_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3786 domain-containing protein"
                     /protein_id="HDF2767441.1"
                     /translation="MDENITKNNYNVPFDYVRKKLKELDPHTISNLSNIPFNNDLNRF
                     TLNFFDRQYIIDYPSGEVWNSNGSLCNNFELKILIVRYLINAKGIPRTNKYVTFKEIP
                     GGNVYYPNFLNRTLYRLSEVFTSQIDKYKLVMEKIGAEKVNMGDLAYRFTYMGNTSMI
                     FILWFGDDEFPPNSNILFDSNIVYYFNAEDLAVVPDTAINAILNKINQL"
     gene            732..1565
                     /locus_tag="PC466_000002"
     CDS             732..1565
                     /locus_tag="PC466_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prenyltransferase"
                     /protein_id="HDF2767442.1"
                     /translation="MNVENQSLSDIEIILSHRYDNGADYWTTPDKRLIKGSPFSTLDS
                     VLYLLELGVNPDDTLLKECADLIFSTWREDGRFKLYPNGGIYPCHTANAANVLCHMGY
                     ASDIRMQKTFQHFLDTQYTDGGWRCNKFSFGRGPETEYSNPLPTLNILNAFRFSNYLN
                     KESKLDKAVDFLLDHWTIKKPLGPCHYGIGTLFMQVEYPFRNYNLFLYVYVLSFYNRA
                     KKDKRFLEALKILESKMIGNKIVVERVVPKLSKLSFCKKGESSEIATTHYYEILKNLE
                     K"
     gene            complement(1661..2449)
                     /locus_tag="PC466_000003"
     CDS             complement(1661..2449)
                     /locus_tag="PC466_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2767443.1"
                     /translation="MCILELIKFELKKIELKHVLIFVIISILCIFITGILDYNELIFY
                     NDVPIMDTYSIAGWLGIIKISDVFIPIMSAITIIYVFSKDYLGNINEILTLYNKKKYN
                     QFIVFRWCVILAIYTVLLLISITIVYTFTSVKGFNIDKIDFVYSVKPIDVFLKTFPTL
                     LWYTTFPLMILTLTKNRFTTIAILITYTFADIFFILHMYPFVSMINVNGFYIQKMFYM
                     PNNIDVRFNELKNYFFINRGSLVVISIIIVFYIARKSTVLKKSK"
     gene            complement(2450..3322)
                     /locus_tag="PC466_000004"
     CDS             complement(2450..3322)
                     /locus_tag="PC466_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF2767444.1"
                     /translation="MINKLEIRNLNFNYKNKKALDNINLTLTDGVVALLGPNGAGKST
                     LMRLLVTLYETSIGEIELNNIKYSKNNEKIKANVGYIPQDFDMYNNINGQEYLEFVAK
                     MRGVSKNDLKKHIQKVVSKVNLDKFINNKIGTYSGGVKRRLGIAQALIGDSKLIVMDE
                     PTVGLDPEQRNEFRRLLPEISKNSIVLISTHIVEDIQFNCDKLIILNQGKILYDGTIN
                     KFIDMVEVYSVVVSNDEFEYLERNIDIIDYRRVKDGVQVKYIGKNTEKLKDSLRIDTT
                     LQDAYINFLHKELK"
     gene            complement(3337..5115)
                     /locus_tag="PC466_000005"
     CDS             complement(3337..5115)
                     /locus_tag="PC466_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2767445.1"
                     /translation="MNLLNIVESIVSCIKGLARRGINMSSIKVISDFITKIIRKNILF
                     AITVIIINYHLIQRWTHISNRGISFNDYLSLSVYTCMTISILTMLNVIFYMRKSYDTV
                     KILCRNNFDYFLGISVAVTRNNFIFCCIPIIYAIAYSSLIRTLSIVTIKSTIFILVFE
                     WFLPLTILSIVISFISVIINNLILKITLSSVFLYLTSTKMLDRVIDIKEPFFKALFKS
                     LNIFEDQSYAYYSDFVGKVNNSAYVIDKIIPTLFAITLIIVAYLILNDIRKKQIKSLI
                     VIVVYSILFIGLNYISIDMSTYRDEERSYGEYLKKSNISDIKIKSHDMKIDFKSKSNI
                     KDRIVLLNTSNEELTNINMILDEIFDIKYIKVNSENIKFNKKKDLIEVNLKESLEPND
                     EVTLDIEYEGYINVLTSWNQNKYIATKDDIMLPPGSLAWYPKVNQSSCMAYKINLSSK
                     NNVYSNLPLLNKTSNFLKKDYIFEGKSNDIAIYAGEFKEEVKDDIKIIYPSDSNVNMD
                     IEEKIKFLIETRNEILGDSKASVDAKKYVDEVDNVMESIKRKKINMILVADLPSNEFL
                     YEDSKGEKISITIYHWLSGNILIIDK"
     gene            complement(5192..5773)
                     /locus_tag="PC466_000006"
     CDS             complement(5192..5773)
                     /locus_tag="PC466_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HDF2767446.1"
                     /translation="MFKRLSYKFANILVNNEIVESEDFEIYRYGFETLIYFIVNISVA
                     LFIGIIFDRFIHTVIFLSCYCTLRQFTGGYHARNYKECTLTFAVIYLITIFSANNIDI
                     NKYKYLLVLLMIISILTIYKLAPLEHRNKPLSESEKKHYRKTVQKILFVIICLIILCK
                     ILNIFQQYVIYAIISIYWIAILIYIGMKVNNDQ"
     gene            complement(5832..5972)
                     /locus_tag="PC466_000007"
     CDS             complement(5832..5972)
                     /locus_tag="PC466_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic lactone autoinducer peptide"
                     /protein_id="HDF2767447.1"
                     /translation="MKKIALNLLKNISALSFGIAVLSANSASSWVAHQAKEPQALQKL
                     KK"
     gene            complement(5984..7300)
                     /locus_tag="PC466_000008"
     CDS             complement(5984..7300)
                     /locus_tag="PC466_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HDF2767448.1"
                     /translation="MLTNLSIGFWNIINLVSGTIDWIIFFLVIHLVGKRKISNIRYIF
                     TTIIIFIFMAYINVVKVFPNIKILLCMVIGISFYITSYEDKIYKSIIVSLLFWLGLMI
                     AEGSAVGLVVFINKLNNINITQHENLFRIQAIIMSKVFLFIGFILFKYFKLSLDFKPK
                     DMILIGIPILSNIVSLLLIFEYNLRVNTITTENLFIFIFAILLILSSSIILLIVIGKI
                     VQDDKLNLEYELINERIKTNYRNYENINEVHDRLKYVYHDLKNHMICIKNYDTKEEII
                     SYIDNLEFQISEFEHFKNTGNKTLDLILAEKISICKKYDIQIEDNINISKLNFIENND
                     ICSIFANSLDNAIEACMDINNELEKRIEVKATYINKFAIIKFINTKVNDIKLIDKRIQ
                     TSKDDDKIHGIGLASIKYIVNKYGGETIVNYSDNEFILKIMIPIKS"
     gene            complement(7294..8004)
                     /locus_tag="PC466_000009"
     CDS             complement(7294..8004)
                     /locus_tag="PC466_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2767449.1"
                     /translation="MISIGICDDELHYRIKIKDILSEILSSYPINYNIYEFSSGEELL
                     NNYPKDLDILIMDIQMKTINGMDTARKIREFDHKLEIIFVTSFVEFMQEGYEVKAYRY
                     ILKPINKEKISKSVLPCINEMMKKRNNYLTINVKNYVDRIKIDSITYIETDRPNILIY
                     THDDMYITKMSISKIEKILNEYGFFRCHNSYIVNLKLVESMSGSTVIVDGKSIPISKY
                     RVKGLKLAITNILGDIVC"
     gene            complement(8442..9017)
                     /locus_tag="PC466_000010"
     CDS             complement(8442..9017)
                     /locus_tag="PC466_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1062 domain-containing protein"
                     /protein_id="HDF2767450.1"
                     /translation="MKKITWEVEYISQLPVIRYCKKCGKKTEYICSGLFRVNAQHKYL
                     DIWLIYKCSNCDSTWNSTIYSRVNPKSLNPETLEQFHTNDYNLAKQYAMNTELLHRNG
                     AEVGIPEYKIVGQEININDLTQVHIISKYPCQLKVSTLLREKLGLSRKVFDEMLDCGI
                     IRSNSGVDLKKGKLNYEIMLDIGKEKQKSSN"
     gene            complement(9310..9588)
                     /locus_tag="PC466_000011"
     CDS             complement(9310..9588)
                     /locus_tag="PC466_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2767451.1"
                     /translation="MSYKKAIHILPEELLELIQEYVDGEYIYIPRKSNNKKEWGSSTS
                     TREDLSIRNMQIYEDYQVGYDLKYLSEKYYLSLKSIQRIVLQEKRKDS"
     gene            complement(9897..10658)
                     /locus_tag="PC466_000012"
     CDS             complement(9897..10658)
                     /locus_tag="PC466_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase"
                     /protein_id="HDF2767452.1"
                     /translation="MKNKIETSMNNFVKNYHKSNNITTKWQELLFAYASAEDDMFQKL
                     KSVVGTSHAMPKDFLENGKTIITYFIPFDESVNNSNIGGFECSEIWARAYIETNMLIS
                     NLNDFLCEELEKMGANSYAIPGSYNFDSEKLVSDWSQRHVAFIAGLGTFGLNNMLITE
                     KGCCGRIGSIITSLELEPTKRPENEYCLYKHNNSCKKCVNKCVKEALKEDGFNRNKCY
                     EMCMINEKKYTYIGGCDICGKCIVGVPCSVINPSR"
     gene            complement(10827..12866)
                     /gene="bclA3"
                     /locus_tag="PC466_000013"
     CDS             complement(10827..12866)
                     /gene="bclA3"
                     /locus_tag="PC466_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like exosporium glycoprotein BclA3"
                     /protein_id="HDF2767453.1"
                     /translation="MLLIMSRNKYFGPFDDNDYNNGYDKYDDCNNGRDDYNSCDCHHC
                     CPPSCVGPTGPMGPRGRTGPTGPTGPTGPGVGGTGPTGPTGPTGPTGNTGNTGATGLR
                     GPTGATGGTGPTGATGAIGFGVTGPTGPTGATGATGADGVTGPTGPTGATGADGITGP
                     TGATGATGFGVTGPTGPTGATGVGVTGATGLIGPTGATGTPGATGPTGAIGATGIGIT
                     GPTGATGATGADGATGVTGPTGPTGATGADGVTGPTGATGATGIGITGPTGATGATGI
                     GITGATGLIGPTGATGATGATGPTGVTGATGAAGLIGPTGATGVTGADGATGATGATG
                     ATGPTGADGLVGPTGATGATGADGLVGPTGPTGATGVGITGATGATGATGPTGADGLV
                     GPTGATGATGADGVAGPTGATGATGNTGADGATGPTGATGPTGADGLVGPTGATGATG
                     LAGATGATGPIGATGPTGADGATGATGATGPTGADGLVGPTGATGATGATGPTGPTGA
                     SAIIPFASGIPLSLTTIAGGLVGTPGFVGFGSSAPGLSIVGGVIDLTNAAGTLTNFAF
                     SMPRDGTITSISAYFSTTAALSLVGSTITITATLYQSTAPNNSFTAVPGATVTLAPPL
                     TGILSVGSISSGIVTGLNIAATAETRFLLVFTATASGLSLVNTVAGYASAGIAIN"
     gene            complement(12933..14009)
                     /locus_tag="PC466_000014"
     CDS             complement(12933..14009)
                     /locus_tag="PC466_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDF2767454.1"
                     /translation="MIAISLCMIVKNEEEVIGRCLECVKDIVDEIIIVDTGSTDSTKE
                     IVSKYTDMVYDFEWIDDFSAARNFSFSKASKDYTMWLDADDIILEADREKLLKIKESL
                     DTSIDIVMAKYNVSFDENGNPTLSYYRERLFKRSSNHKWVDPIHEVVPLFGEVFYSDI
                     AISHKKLHRQDPLRNLRIFEKMISEGKTLEPRHQFYYSRELYYNARYKEAIEGFTKFL
                     DSSRGWIEDCISACRDLATCYYLINDEKSALYSLFRSFEFDEPRAEICCDIGKHMFDR
                     QKYKEAIFWYKVALTRDKNDTNGGFKSNDCYGYIPSIQLSVCYDRLGESDKAIYYHEK
                     TKEIKPNDSAVLHNENYFSKFKNS"
     gene            complement(14331..14915)
                     /gene="clpP"
                     /locus_tag="PC466_000015"
     CDS             complement(14331..14915)
                     /gene="clpP"
                     /locus_tag="PC466_000015"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HDF2767455.1"
                     /translation="MSLVPHVIEQTGQGERSYDIYSKLLKDRIIFIGEEINDAIASLV
                     VAQLLFLESEDPDSDIIIYINSPGGSATSGFAIYDTMNYVRCDVSTICIGMAASMSAF
                     LLAGGTHGKRCALPNSEIMIHQPMGGAKGQATDVKIAVDNILKIKERLDKILSENTGK
                     SIEDIRRDTDRDNFMTALEAKEYGLIDYIMNRNE"
     gene            complement(14912..15370)
                     /locus_tag="PC466_000016"
     CDS             complement(14912..15370)
                     /locus_tag="PC466_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2767456.1"
                     /translation="MEIIDYIEENLTENLNLDKIAYIANYSKYHLHRMFTNVVGCTIH
                     QYIQRRRLTEAARQLIFTDKYIIDIAITVGYSTHQSFTLAFRNLYKESPQVYRNKDEF
                     YPIQQRFVLNLNHQIQSEKCISYANMNYKQRRDEINSYLNFNINCEVKVA"
     gene            complement(15593..17008)
                     /locus_tag="PC466_000017"
     CDS             complement(15593..17008)
                     /locus_tag="PC466_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HDF2767457.1"
                     /translation="MWITINRNSNISLSRQIYCEIKDMILDGSLKFEQKLPSSRTLSK
                     ELSVSRNTVLDAYNQLIAEGYLETRNGYGTIVAKGISGHKVDFKLNDTFRDEKDLHTN
                     KQKNYIDFRSGVPELKLFPRKELSKLYKQILYDLSDSDFRYGSTAGVWVLRVEISKYL
                     FRTRGIRCNSKNIMIVSGSTQGLSLISQLLYKSNKKVAVEDPIHKGLLKVISSIGYSV
                     VGIKVDDKGMNTNLIKSIKGISFVYTTPSHQYPLGGILPIQRRLELIKCATENDYYII
                     EDDYDSEFRYEGQPISSLYELSPNKVIYIGSFSKILSPAIRVGFMLLPDNILESYKTL
                     KMYSDVHTETILQYVLAEFIGNGGLEKYIFRMKKLYNRKRKYLIKVLNTEFKNEFKIK
                     GEAAGLHIVAHFYNVKFTESLIHKIFEAGIKVYPIQQYAIENILEYDHEIILGYAHLS
                     FDEIEKGVKILSKIIHMNQGT"
     gene            17123..17791
                     /locus_tag="PC466_000018"
     CDS             17123..17791
                     /locus_tag="PC466_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2767458.1"
                     /translation="MLEISHKVKEIYPNIKFGVMVINITHSKPNKENFLVLKNSTIKN
                     IIEQHPEYNRKEKIKTEPVSSYIKYYKKFKKTYPVLLQLESILLKSKGIPDVGVTIES
                     MFLAELKNLLLTAGHDLDKMELPLKIELANGSEHFYGIGGKEHILTKDDLFLSDNIGI
                     LSSILNGPDNRTAITKDTKNIMYFVYGPDKISEKQIQDHLNDIKHYISSAFPDLKVNS
                     IDIF"
     gene            complement(17967..18485)
                     /locus_tag="PC466_000019"
     CDS             complement(17967..18485)
                     /locus_tag="PC466_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDF2767459.1"
                     /translation="MNFVELTKKRYSCRNYQDRKVEKEKLEKVLDVARIAPTGGNRQP
                     QRLIVIQEKEGINKLSKAANIYDAPLAILVCGDKDKVWTRPFDGRQLTDIDTSIVTDH
                     MMLQATELGLASVWVCYFNPDIIREEFSLPDNLEPINILLMGYESKIPESPERHEKTR
                     VPLSEIVSYETL"
     gene            18637..18960
                     /locus_tag="PC466_000020"
     CDS             18637..18960
                     /locus_tag="PC466_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2767460.1"
                     /translation="MKKCLDNYSCPIEATLALIGGKYKTLILWHLKDTILRFNELKKL
                     IPKATPKMLTQQLRELESDGLIIRVVYPVVPPKVEYSLSDFGKSIIPILDSMCDWGSD
                     YLESL"
     gene            complement(18965..19549)
                     /locus_tag="PC466_000021"
     CDS             complement(18965..19549)
                     /locus_tag="PC466_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HDF2767461.1"
                     /translation="MKVLVFLAKGFETMEFSVFVDVMGWARNDYGHDIDVVTCGFKKQ
                     VMSTFNIQVLVDKTIEEVCVDDYDALAIPGGFEEFGFYDEAYDSSFLNLIREFNSKEK
                     IIASICVAALPVGKSGVLKNRKATTYHLKNGKRQRQLSEFDVNVVNEPIVVDKNIITS
                     YCPETAPHVAFKLLEMLTSREQMDEVKLAMGFKL"
     gene            complement(19598..20053)
                     /locus_tag="PC466_000022"
     CDS             complement(19598..20053)
                     /locus_tag="PC466_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HDF2767462.1"
                     /translation="MDEIDLKIINSLKKNSRASTSEISRQINLSVPAVSERIRKIEQS
                     NLIQKYTIQINREKTKYKLLAFIFINTDLSKSMKEFKKTILEYDTVLECHHISGEYDY
                     LIKVLAEDTSNLEEFISVTLKEIGGIQKANTTIVLSTIKEEFNTIKDIF"
     gene            20936..22474
                     /locus_tag="PC466_000023"
     CDS             20936..22474
                     /locus_tag="PC466_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HDF2767463.1"
                     /translation="MSLLKVTNLSQCFMDKSLYEKANFDLFKGEHIGVVGQNGTGKST
                     LIKILLGEVVPDSGEIKWQPNINIGHLDQYAEINRDTTISLYLHTAFEELYKIEKEMN
                     LLYQKSAISENEQYLIKASDYQEQLIASNFYSIDNEINKIANGLGLDSIGMNRVVEEL
                     SGGQRAKVILAKLLLSNHDVLLLDEPTNFLDKEHVEWLSNYLNTFNGAFIVVSHDFDF
                     LEKISTGILDIEFGMIKKYHGKYSEFLKQKSHLREDYIRRYQAQQKKIEKEETFIRKN
                     KAGVNSKIARGRQKQLDKIERIAPPSFTGKPNIQFSEIEISAQNALTITNLEVGYYYS
                     LLPKLNFSVDGGQKIVITGFNGIGKSTLLKTLVKDIPRISGDFQFSEQVKIGYYEQDL
                     KWENPDKTPLQIVADKYPKLNTKEIRRHLARCGVKEEHVSRSVSTLSGGEQSKVKLCC
                     MMLSPCNFLILDEPTNHFDAETKDALQNALKQFRGSIILVSHEEKFYKGWIDKVFNIE
                     KQLV"
     gene            complement(22746..23459)
                     /locus_tag="PC466_000024"
     CDS             complement(22746..23459)
                     /locus_tag="PC466_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2767464.1"
                     /translation="MDTYFNKKILLVDDEKDIVDLIEEVLINDGFKNIIKAYNGLDAI
                     SLCKIACPDVVILDIMLPDIDGIEVCKKIREFSYCSILFLSSKNDDIDKILGLSSGGD
                     DYITKPFSPREIAFRVKAQLRRQQYQSIVPSDSAVIKIGDITIDIEGNRVYKDRNEIE
                     LTGREYHLLSYMAQNVNKIIGKERLYEQVWGVYSSICDNTIMVHIRHIREKIEDNPSN
                     PKILITVKGLGYKLVNRID"
     gene            complement(23914..25293)
                     /locus_tag="PC466_000025"
     CDS             complement(23914..25293)
                     /locus_tag="PC466_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF2767465.1"
                     /translation="MSDVYYSENHEQDNLYEQDNLLAQRFNLFTLLKFAFPTIFMMIF
                     MGLYTIVDTIFVSRFINTNALSAINIVCPIINLIVGIGTMLATGGSAIVARKMGNGDI
                     EGANKAFSLIVLSGVVIGVIITGIGIVFMDYIIIWLGASEVLIKYCRSYLFIILVFAS
                     ANILQVLFQCLFVTAGKPQFGLWLVLGAGCANIILDYVFIVLLQMGISGAALATGVGY
                     LIPTVSGMVFFSKNKELLKFCIPRLDKRILFEACFNGSSEMVGQLSTAVTTFLFNAMM
                     MKLIGEDGVAAITIIIYSQFLLTSLYIGFSMGVAPIISYNYGSENNTQLNHVFKICIL
                     FISVASLLVFIFSISCSPIIVEIFSQRGSRVYEIARSGFYIFSFSFIFCGYNIFTSSM
                     FTALSNGKVSAILSFLRTFGFITIGLLILPNILNINGIWLAVPSAEILTLFLTIFCIC
                     KYKNRYKYM"
     gene            complement(25578..26372)
                     /locus_tag="PC466_000026"
     CDS             complement(25578..26372)
                     /locus_tag="PC466_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HDF2767466.1"
                     /translation="MMKKNLKIIFMLLKMKLSKMMVFRFDFFGAFFVDSSLFILQLLM
                     FNSIYSHVDSIGGWQQGEMLIFIGTFSLINAINMTIFFFGIYDIPRKIQEGELDYYIT
                     KPLDPLFRLTFENINIGSSPLILASILIVLYGISKLNSEITLVMIIIYIFMVLLMTLL
                     FYDVCIILRTVSFFVISSSAIMRLEDNLLPMNMKIPGVIYEGVFKVLFYLILPYGIMS
                     TIPTQILAGTITINGLIYSILIVFLFTLFMWRFWKLGMRHYKSASS"
     gene            complement(26369..27232)
                     /locus_tag="PC466_000027"
     CDS             complement(26369..27232)
                     /locus_tag="PC466_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HDF2767467.1"
                     /translation="MSIMSNYNEASSNYSMFYKFKQSIRRYYEVAKINFKVQLIWRFD
                     VVVNMVFTIVKILFAYILWKAIFGENKIVSGFTFNSMLSYYIISSFLAGIDMSKSTSE
                     EICNRVKLGTFSKYMIIPINVQNYFIAKNFGMTCFYFVFNMISAFVWIFIFKIDFAFT
                     SNPVQILISILMIFLGFIFMMKLHFFIGILSFKFLEISFFRMIIENIVEFITGTMIPL
                     VLLPETIVTVMKVFPFYYTTYLPSMLLIGRNSNEAIQGLIILALWVLFFSVVNKVMYK
                     RMRTLFDGVGI"
     gene            complement(27210..28205)
                     /locus_tag="PC466_000028"
     CDS             complement(27210..28205)
                     /locus_tag="PC466_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF2767468.1"
                     /translation="MSIIELNELTKSYRRFEKKAGFMGSVKSLFNRKYTEKTAISSFD
                     LKIEEGEFVGLIGQNGAGKTTLIKMLTGIIAPSSGEISVMGYYPNKLENNFKKQYAVV
                     MGQKSQLFFELTPADTFLLFKELYDISNEEYKKNLDYFIELFEVSDYLNVQVRTLSLG
                     ERMKMELIVALLHNPKILFLDEPTIGLDAIAQKQIRYFLKEVNETKGTTIILTSHYME
                     DIKSLCSRSIVVENSRKIYDGSTEKLFNHFQKYKKITVSFSNETNIVFPKDCKVVEQT
                     NHKTSVIVLKERGNETIKWIFDKYDVKDVMIEEEDIGSIVERIYKKGSDEYYEQL"
     gene            28908..29864
                     /locus_tag="PC466_000029"
     CDS             28908..29864
                     /locus_tag="PC466_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HDF2767469.1"
                     /translation="MENNTIQKQLRDLSKKIWHIYILNPEEENLKFIISLLDNNLALI
                     GTGKHEFYETLEEFIIGLEKDQTESEQIDFEIIDEWYSCTKVTDEAFIVYGTLWVIEK
                     DYLEKDIYVEMDTRFTMVYRVTDDMIKLIHVHHSIPNFDQMKDEYYPKTITEKAQEAL
                     AMANEFKLKSEKDLMTGLYNRHFFEVHIKEMLKTVSYGYFYIFDLDNFKQVNDIFGHV
                     RGDEILIQFSNILTKVFVNDAIIGRLGGDEFAVFEYSNQSKENVENKAKKVLELCLES
                     NSCSIGISKLENKSDTFQSLYKQSDYALYYSKRNNKGNFSWF"
     gene            complement(30265..30813)
                     /locus_tag="PC466_000030"
     CDS             complement(30265..30813)
                     /locus_tag="PC466_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2767470.1"
                     /translation="MEGLGFYAAALSGSSYQRIGFGKLDPIEVIADGDWISYKQAQDT
                     LTVIRNFLNSFDWRNASEMERANRAAKLVTEAKYVDSKYCNIVYGNLVDKRGVCGSFA
                     SSFHLLTRLMGMDSLSILNPSLNHAWNYIQIDGKWYRSDGSEISAFGGALDFDYRKLK
                     DATREMTTYYDAKALSILGFNQ"
     gene            complement(30915..31613)
                     /locus_tag="PC466_000031"
     CDS             complement(30915..31613)
                     /locus_tag="PC466_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2767471.1"
                     /translation="MKISSQYRSQYSFRHESNINNTRINESMVKKNETVGKDTYLSNI
                     MKQKQELNDRIRDLKYRQEVYTKKINEAIKNLYKSEIRETTNNFSNIEIGIKNSIIED
                     KNKSTMLDENSTYLNTNDEKESLITKESNEKIEEEILNDEKLEELEQKKDYKEDSNKK
                     EKVSEDLSLVGKTREELENMLKNFINLTQEEIMKLESRIEKLDKDAEEYKQNSKTNIF
                     DKTDEQKKHINVLI"
     gene            complement(32149..33216)
                     /gene="rsgA"
                     /locus_tag="PC466_000032"
     CDS             complement(32149..33216)
                     /gene="rsgA"
                     /locus_tag="PC466_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HDF2767472.1"
                     /translation="MNGMKQINLQDYGLNRNFITQSMEYHDLYLARIISQEKNFYQAV
                     CVNGVLFAEVSGKLRFEATIQSDFPTVGDFVMLDRCNNKNGNAIIHHVLHRKSLFVRK
                     AAGKVNEEQVVAANIDIVFLCMSLNKDFNIHRLERYLSLTWESGAIPVVVLTKSDLCD
                     NVHRKLQVVNSIALGVDVVVTSSIEPDGYKQISKYIKSGCTVALLGSSGVGKSSLINC
                     LLGGEFLNTKEIRIDDDKGRHATTRRELFLISGGGIVIDTPGMRELGMWDVSEGLDKS
                     FADIEAYFGKCHFRNCTHTSEPGCAIWEAIAHQELSPKRWESYRRLKTEAVFADNKSE
                     YLAKKEKKFKNISKINKTIRR"
     gene            complement(33213..33614)
                     /locus_tag="PC466_000033"
     CDS             complement(33213..33614)
                     /locus_tag="PC466_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNHCP domain-containing protein"
                     /protein_id="HDF2767473.1"
                     /translation="MNYKNRKRAYYQENSCMDNFICKNCGCLVVPEGAGTQHRNHCPH
                     CLHSLHVDIIPGDRAADCDANMEPIGVWVRKNGEWAIIHRCTRCGHLSSNRIAADDNS
                     VKLMSIALKPLAQPPFPLERIIEKLEKEETE"
     regulatory      34410..34506
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            34560..34736
                     /locus_tag="PC466_000034"
     CDS             34560..34736
                     /locus_tag="PC466_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2767474.1"
                     /translation="MFRDKMDRCTHMLTAYIGSSYDYCDFIDTQLDDFILEYGENVVE
                     SCLHQVMVLVSKYN"
     gene            35146..35784
                     /locus_tag="PC466_000035"
     CDS             35146..35784
                     /locus_tag="PC466_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2767475.1"
                     /translation="MSNQIKDFDITNDMFQESIPITTKTILEDMPSNDELNHVFSKGC
                     ERKMKKRKIVLITLLLIGVLLLGSILYNLFLVKAANISMLKESWNFDIPIPNKEIEVF
                     DTQDSINGDGQSYFIQGFSEKNFKKVFNLKGGIVVSKDNINEIEKYIDKFKRDSVNIN
                     KSNKNKIEEDFKKYKLEVKKDDKYIYKRNYENYVVLIIKKDEQKLYSLIWNQ"
     gene            complement(36262..37938)
                     /locus_tag="PC466_000036"
     CDS             complement(36262..37938)
                     /locus_tag="PC466_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDF2767476.1"
                     /translation="MSKEKIKVYLYTRVSTSIQIDGYSLEAQKSRMKAFALYNDYEIV
                     GEYEDAGKSGKSIEGRVQFTRMMEDIKSGKDGVSFVLVFKLSRFARNAADVLSTLQIM
                     QDFGVNLICVEDGIDSSKDAGKLMISVLSAVAEIERENIRVQTMEGRIQKAKEGKWNG
                     GFAPYGYQLIDGKLIINEEEAIAIRTIFDQYVNTSIGANGLSKYLENHGIRKIPRQNG
                     KNPLFDAGLIRKILKNPVYNGKIAFGRRTLEKVHGTRNEYRQVEQDDYLVAEGIHEAI
                     IPDELWQAAQVKLKAQAKKYEHVNKGKNMRTHLLSGIVKCPICGAGMFGNKSIKYKKD
                     GTKYKDFYYYGCKHRLMNRGHKCTYNKQIREELLDDAVAEVIIKLVSNPKFASMIQEK
                     INMKVDTSAIENEIDNYQNELRKSHSTKYKLIEEIDNLDVEDKHYKRRKNDLDDRLYR
                     MYDKIEELESQLIEAKAKKETIEVEKLTGDNIYKVLIYFDKLYKVMNDVERRQLIEAL
                     ISEIQIYEEKQPNGQWLKSITFKLPIIDEDLNISLENDEQVETVAKIIKQ"
     gene            complement(38039..38191)
                     /locus_tag="PC466_000037"
     CDS             complement(38039..38191)
                     /locus_tag="PC466_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2767477.1"
                     /translation="MDNDWNGLADLIANLITKYAGVLDLENLPNPTPVKNTEDKNKFD
                     IAKSTD"
     gene            complement(38680..39090)
                     /locus_tag="PC466_000038"
     CDS             complement(38680..39090)
                     /locus_tag="PC466_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004634151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDF2767478.1"
                     /translation="MAKEYYLYIRGQKVKVSEDIYIVYWREKEHEKYLEQVDRKNHLL
                     FFSALDHDGHFTDNIVDESVDVEKIVETQMMIEAVRSAITRLNAEERDIIERLYFNDE
                     TVRSVAKLKSITHPALIKRRNKILEKLKKFIEEL"
     gene            complement(39614..40933)
                     /locus_tag="PC466_000039"
     CDS             complement(39614..40933)
                     /locus_tag="PC466_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2767479.1"
                     /translation="MKKLKIFPKMFIQIFSVLGIIIILVHSLVFFIFPKTYLETRKEK
                     IHNMANEISSNMNGKEIKYIEQTLELYSKSSEIKAFIKEKNNKNEIQIKDNINVNLES
                     DSNSLIIEEREIKLNDGKKTNLQFVSTADMQKDAKDLSLKFLPYSLLISILFSAIISL
                     IYAKSIKNNIQEIKIVTDKMMKLDKKTRLKVSSNDEVGELKQQINDLYSTLLRTIDDL
                     EFKNKEILKLEKLKYDFFKGASHELKTPLASLKIILENMKYNIGKYKERDIYINECIE
                     IVDSLTKNISQILSVHSIENLNNDEEYLKINDTLEDILKKYEILANQKKITVNNYILD
                     ENVYIGKTALKIILSNLISNAVKYTDVNGVINIGIVNDWLYIENSYGNNKISNMDKIF
                     DVKFDLNKENSNGLGLYIVSNILNNYNIEYKALQDEEFFIFKIKIFS"
     gene            complement(40930..41583)
                     /locus_tag="PC466_000040"
     CDS             complement(40930..41583)
                     /locus_tag="PC466_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2767480.1"
                     /translation="MKILTVEDDNMIREGISEYLSEFGYTVIQAKDGREALSKFNSDI
                     NLVILDIQIPFINGLEVLKEIRKKSNLPILILTAFSDEEYKIDAFTNLVDGYVEKPFS
                     LPVLKARIDSLIKKNYGHLEKFEYNDLSVNFNSYTAKINGEEIDVNAKELEVLKCLLD
                     NNGQVLTRMQIIDYVWKDSEETPYDRVIDVYIKELRKKLQLDCITTIRNVGYKLERK"
     gene            complement(41681..43057)
                     /locus_tag="PC466_000041"
     CDS             complement(41681..43057)
                     /locus_tag="PC466_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2767481.1"
                     /translation="MIKNAFAYVTRKSLKSLIIILVILSMSTLSLISLSIKDATDRAS
                     KETFANITNSFSMEINRQVNPGTPRGGGNVKGEDIKKIFQTDSIDSYVKRINSVADLV
                     DYDIIETQETLANQSPERAKNFKRTVMLTGVNDSSKETKFVSEAYKLVEGKHLENEDK
                     NKILMHKDLAEKNNLKVGDKIKIKSNLFDADNEKGADETVEVEIKGLFDGHNSGGVSA
                     AQELYENTLITDVHTAAKVYGNTEDTAVYQDATFFVKGDKNLDSVIKDLGKLDINWRE
                     YNLIKSSSNYPALQQSISGIYSISNKLFVGSLIFAGVVVSLLLFLWMNARKKEIAVLL
                     SLGISKLEIFGQFLIEMVFISIPAFVGSYFLAQYTADKLGNNILNKVTGDIAKQIARQ
                     SASSQLGGGAEAEGFNKTLSSLDINVLPKFIIYVVIFMSLVLLVSLIISSFNILRRNP
                     KELLIDNN"
     gene            complement(43057..43713)
                     /locus_tag="PC466_000042"
     CDS             complement(43057..43713)
                     /locus_tag="PC466_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2767482.1"
                     /translation="MDILEIKNVAYSYANSKEKVLSGVNQKFELGKFYAIVGKSGTGK
                     STLLSLLAGLDKPQTGKILFKNEDIQKKGYSNHRKNNISLVFQNYNLIDYLSPIENIR
                     LVNKSADESILFELGLDKKQIKRNVMKLSGGQQQRVAIARALVSDAPIILADEPTGNL
                     DSVTAGEIINILKTLAKDRNKCVIVVTHSKEVADSADIILELSGKKLKKVNKMNLEVE
                     "
     gene            complement(43723..45000)
                     /locus_tag="PC466_000043"
     CDS             complement(43723..45000)
                     /locus_tag="PC466_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2767483.1"
                     /translation="MIKNAIAYITRKRNRTLIIFIILTIVLSCLYSCLTIMKSSNEIE
                     KALYESSNSSISITKKDGKYFNVNQFKDIEKLKEIEEKIIQYDGLAKLKDAKVVSGEQ
                     RINREDLSDEFKNVVSLEATNNTKRNILFSSGVFTIKEGKNIGENDKNSIIVHEEFAK
                     QNNLKLGDEVDLELLDIEKSGKIKSHKFKIIGIFSGKKQETYTGLSSDFSENMVFVDY
                     STSQEILNKSENNKIANKILMYSGSAESTDLALNKLKELKIDESKYFVEKDSNAFEES
                     LESVSGIKHIIKIMTYSIMLGGMVVLSLILILWLRERIYEIGIFLSIGTSKIQIIMQF
                     IFELIFISIPSIISSLFLGNVLLKVIVDGFINSEDSMISGGSLINNSSFMLNITTLGQ
                     SYLILISIIVLSVVFASSLILIKKPKEILSKIS"
     gene            complement(45019..45909)
                     /locus_tag="PC466_000044"
     CDS             complement(45019..45909)
                     /locus_tag="PC466_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDF2767484.1"
                     /translation="MDRIKNIINGSTKKDKYKIRDRFRHLFQSVWFLITNSYFEGFKT
                     GKIYGGNLKKICVPGMNCYSCPGAKGSCPIGSLQAVIGNSKYKISYYIVGILFFIGAL
                     VGRFVCGWLCPFGLIQDLLHKIPFFKKVETFKFDKHLRKLKYIILLVFVIILPLFLVD
                     ILGQGSPYFCKLICPIGMLEGGLPLVLLNKSMRNAIGFLYYWKGIILIVTLLLSIIIY
                     RPFCKYICPLGAIYSIFNPISIFRYRLDKDKCINCGKCKKVCQMNIDPVENCNHLECI
                     RCGRCKNACPVDAISYGVRK"
     gene            complement(45902..45997)
                     /locus_tag="PC466_000045"
     CDS             complement(45902..45997)
                     /locus_tag="PC466_000045"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HDF2767485.1"
                     /translation="MAMIYYGHSNGETKVVLDKAIRICMECIGIG"
     gene            complement(46076..47233)
                     /locus_tag="PC466_000046"
     CDS             complement(46076..47233)
                     /locus_tag="PC466_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HDF2767486.1"
                     /translation="MKKIVSRGACLLLTLCLSLSTVGCKKSNESNKIKEGQSISSEEA
                     GMSTNEKDKNETFKPSDYTLKTKKEYVYEYLGLKFKLSDKFKKYMDDKKIAMLDDQSP
                     IDKELKYAILTFEKMTEEQKNAVIEKMGDGYKNWQNELERIGTIGIFEKNTSEEKISK
                     ITKCDTHTKIGVSSDGKYDCYLSTNSGAESNLLDELKRTEIQIIDKKERPKNGFVLSE
                     KTDLENTEAFNKESVKDLRKLSTKDINGKDFTSKDFEKYDLTMVNVFATWCTACVKEI
                     PDLVEVQNEMKSKGVNIVGVVTDTVDDNGENKEAIEKSKLIHEKTKASYPFLMPDKTN
                     FNGRLNGIQAMPETFFVDSNGNIVGDTYSGAKSSKEWKQVIEKELEKIKNK"
     gene            47567..47917
                     /gene="mobC"
                     /locus_tag="PC466_000047"
     CDS             47567..47917
                     /gene="mobC"
                     /locus_tag="PC466_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HDF2767487.1"
                     /translation="MANRIRNERLEIKLTEEEKALFEEKRKLARCRNMSHFIRKCVLE
                     KEIYQVDLEPFRDLQGLLSNATSNINQIAKRVNSTGIIYKDDINDMKKQIEYFSKELW
                     QIHSLLLNRTSGGD"
     gene            47923..49254
                     /locus_tag="PC466_000048"
     CDS             47923..49254
                     /locus_tag="PC466_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HDF2767488.1"
                     /translation="MAITKIHPIKSTLNLAISYIVNGKKTDEQILVSTHKCHQETAHT
                     QFLRTRNDVGTNGTVLARHLIQSFLPGEASPKMAHQIGLELCKKILKDEYEFVLSTHI
                     DKGHIHNHIIFNNVNMVTGKCYQSNKKSYHKIRYQSDKLCKENNLSVIDEFYESYKRK
                     YKTNGKSWYENEQSKRGTSWKSRLQFDIDRLIKQSKYWEEFLKKMAELGYEIKYGKHI
                     AFKPKDKTRFTRAKTIGEDYTEERLKERITENQSITTPPVKRRIGNIINMNANAKVKE
                     SKGYEYWATKHNLNTMAESVIFIREHGINSIKQLDKYIQKSAEERQDLQDKMKEIDKD
                     MQLLSDTMEQVHTVKKYRAYYKEYKANPSDKAFFEEHKAEITHYEIALSKLKKSYSKL
                     PNSKDILDKLNKLQEKKNTLIQEYSSTKSTMDELYQIRKNYGIYMGKEMER"
     gene            complement(49290..50096)
                     /locus_tag="PC466_000049"
     CDS             complement(49290..50096)
                     /locus_tag="PC466_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009354872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PQQ-like beta-propeller repeat protein"
                     /protein_id="HDF2767489.1"
                     /translation="MEISKKELRKISRKFRILASNVMNSYYGEQNANLEEMINYIEQT
                     LLIKEYLHSLEYDVDGLDDLLNTISNSYGRKVLNLGNDSNKRTYLLYRAFSFITGNNL
                     PTYTFGWYYAGSNKYQDMAKAFGDRMVYPFVLEVENYMKDISTDMGYDENNALYNINV
                     NSSGVQVNIAEHGSTINADQENKFNTEEVIKAINNVEDLIKGMEDDNSKSILNQNLDN
                     IKNEIKQKHPKKEVLTTCLKSMHFITTSVALIPDLALGIKMLASLIGISI"
     gene            complement(50086..50547)
                     /locus_tag="PC466_000050"
     CDS             complement(50086..50547)
                     /locus_tag="PC466_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HDF2767490.1"
                     /translation="MANDIKFEISVPADEEGYVQLKCPSCSEKFMLTVEDIEAESTID
                     IWCPNCGLTHENYLDDDIYELAERIVENQVAEMLNDFSKNLEKSFRNSKSIKFKRGKE
                     IKKEAELPIGRKTGDYEEKKYLCCGKTARISSIKKLEGSYCPFCGEMIDGD"
     gene            complement(50575..51642)
                     /locus_tag="PC466_000051"
     CDS             complement(50575..51642)
                     /locus_tag="PC466_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009354804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UvrD-helicase domain-containing protein"
                     /protein_id="HDF2767491.1"
                     /translation="MSGKLYIAAAGSGKTRKIIEDSLNTHKKILILTYTITNEQQIIS
                     RIKNKVGVIPNNITVSTWFSFLLKDGIRPYQGSRFKERIEGIIFVNGQNNTYVKKTSN
                     KYFAKDNRVYTDKLSECVVELNDKCNGKVFERISGMYDCIYVDEVQDMVGYDLEILKC
                     LIASRIEVIMVGDPRQCTYSTHSSKKYKKYSCGKIDEFLKNECRKLDVRIDETTLNCT
                     YRNNDIICKFANSLYPERTSTNFVRRAEDESDGVMIIDKADVEKYLQKFNAMQLRENK
                     RTSVNNEYPYYNFGESKGLEFQRVLIYPTQPMWDWIINNNTSLKEQSKARLYVAVTRA
                     ENSVVIVRKDARPCSLPVVKL"
     gene            complement(51639..53261)
                     /locus_tag="PC466_000052"
     CDS             complement(51639..53261)
                     /locus_tag="PC466_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF2767492.1"
                     /translation="MSIRKLKIKNFKCFSDWFIVDFENGINILVGNNGTGKSTILEAI
                     NLVLTGTYHGKNIRNELTQYLFNKNIVENYIREVNEGVNVEPPKIIIEAYFDAEMPSF
                     LGDGNSEKTKDTPGICLSISFDEKYSNEYKMLCKNKITSLPIEYYEVSWMSFARENIT
                     ARSIPIKSAMIDTTSYTPTSGSDIYISRIVKNLLDDNEIINISQAHRLMKEQFSRDEN
                     IANINRKLTETSNNELTISVDFGTKTSWESSLVTQLNEIPYNNIGKGTQCIVKTQLAL
                     SDHKIENKQIVLLEEPECHLSYSNLNILLDKVNESVKEKQIIVTTHSSFVSNKLGLEN
                     LILLNRGKTLRLGDLSNETNLFFKRIAGYDTLRLLLSNKAILVEGDSDELIVQRAYMD
                     SHNGKLPINDGIDIISVGISFLRFLEIAKLLELRVSVITDNDGNIDALNRKYSDYLGD
                     NCCENINIYFDDSTHEYNGSLENYNYNTLEPCIYRSNSMSILNEILNKSYEDPDDLLK
                     YMKGHKTEVALKIFESDKAIEFPQYIKEGILI"
     gene            complement(53464..53694)
                     /locus_tag="PC466_000053"
     CDS             complement(53464..53694)
                     /locus_tag="PC466_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2767493.1"
                     /translation="MRVFSYKRLFKKLIDLDMTNNELMEKAKVSKSTFYKMKNGQNVT
                     TDVLLRICNALDCDIEDIMECVIIEDVRRMGV"
     gene            complement(53834..54493)
                     /locus_tag="PC466_000054"
     CDS             complement(53834..54493)
                     /locus_tag="PC466_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006627214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HDF2767494.1"
                     /translation="MDYKTMRDRVEDMLSDNHKDFVKAIISMEKGINDESALDKLYDA
                     YMDNDSLNLLHEEFDYMIEDLRGQGQIKDLLYVREEKDNLINIVGNIVGEVDVIEREN
                     KNGETFKVANFSVVSKDDEGNKLYHNCSVYGEKSDIPKDFKQGDFVKLFGQIRTSIDD
                     NGKEHSNIRILSSKLLKAKEQMKGQEEKKESILGAIKKYQAEDKEKPKEKKEASKEAE
                     R"
     gene            complement(54536..63265)
                     /locus_tag="PC466_000055"
     CDS             complement(54536..63265)
                     /locus_tag="PC466_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HDF2767495.1"
                     /translation="MRINDFHNILELIKQDVLYNEAEYLKLLKVVGNNQRYDFRSQLS
                     IYDKNPEATACAKFDYWRERFNRTVMRGQKGIPILEDYGTYKKVDYIFDISQTVSKNR
                     DVNEVNLWRFDKEAHQDVLKEMIKSEGYEESESTLENIFSLSRLYGDEKIDTLMNELR
                     VADEDRISFTKFVRDSVSYAVASRFKLDYPMDYELLRENFQRFDSISLMSLGESVSDI
                     SGKIIDETIQKSKELELQKEVLIGKEAGYNKIKEELEEVEENVFRRDDQERNENERVL
                     RNGEYGRDNRKNQGEYAKQLGGTDGLYKEVSESDLRSDEAELPFTERGAEPLRDAFGS
                     IQGEEADRTPDGYSETGSRVYESREAKVDSSLEDRGREQSAVWGDDFSSQRNDHQGSS
                     GDLKDNTDKGIIEAEKASFSLPENSYGQISLTIPLTEKDIDTVLINGGNHDGGRLPVI
                     AEFSKGKSIEELGEYLKDTFKGGNGFYIDEREVSSWYSDKGIHLAYGTSAREDNTQIL
                     SWSDAASRINELLDRGEFATNVELLEAQDYERDRISESLWYLTHDLSEEGIEQGYFNS
                     FERGGGFPQETKRLSEALKNPEYLKETIKEYSRFLEGYKESRNVLRYHYHKVDSLYQK
                     LQELELQRKEYSTNLTELPKVKLFITEDEVLESLSRGSGVDRGKERITKFFKENHTLQ
                     EKANFLKDEYGIGGHSHVVSGAMGSDEWHDAKGFKLQKNDCNDVFLTWTSVAKHIDEL
                     LSKKLYFEEKETESTAEIEEVKEPQYYSKNDPGNLMPDEILERVPEIYAQEDVDLADK
                     QVHAAYIIPFRSNWTWYMTEYDRESGDAFGLVLGIEPEWGYFNLEELKELNAQRLILE
                     DFPKTFRELKDIELIKQMDEQELQFVFNGELSFEDKVELEAPEETEEATKRGTVQATL
                     FDYLKEREEVELNEKEDSLLEEFAVKAGDTVYFNHEEYKVREISKNEITGRYDLWLDP
                     VRSGNHQIPIVDFTDNEDLLNKISLERPNFIVGDEVKYKDKNHTITRFDDMRKNLNTV
                     TVKDNTEYFGGMITSFDVIPYRLESDLERVFENLTYKQPEQTTEETQIRKAEAHNFKI
                     TEETLPEKLSPSERLNNNLEAISMLNRVESGQRELDSTAQEVLARYVGWGGLSEVFDE
                     SKEGQWKEARAFLNENLSHAEYEAARESTLTSFYTPKTVIDGIYKTLSDMGFKQGNIL
                     EPSMGIGNFIGNIPDEMNKSKFYGIELDSVSGRIGKLLYPESEVQIKGLEETSFSNNF
                     FDAVIGNIPFGEYKVNDREYNKNNFLIHDYFFAKSIDKVRNGGIIAFITSSGTMDKKD
                     ESVRRYLAARAEFLGAIRLPNDTFKGIAGTEVTSDIIFLKKRDSIRERDEDWIHLAED
                     ENGLTYNKYFVDHPEQVLGTMREVSGRFGNTLACLPKENADLKELLTKASEEISKGST
                     YEEIELLDDEITSIPATDDVKNFSYTVIDDEVYYRENSLFIKKEITDKNKEKIKDYLE
                     LNTALKDVIYKQKEDYSDDEVKKAQEKLNEVYDNFSKKHGFINNLSNTRALKEDSNFP
                     LVSSIEILDEEENVKAKGDIFSKRTITKAKVIDHVDTSLEALVLSVSEKGYVDFEYME
                     SLTGKDRPTLIEELRGEIYLNIREEQNFYRPLSFNLEDGDLPFACANGSNSYKYGYVT
                     KDEYLSGNIRDKIAIVDSYLAKLRQTERELPHLGFVENGKEKELISYEMNRLEYQKAE
                     LTKVLPKELEASEINVRLGATWIPIKDIEKFIFETLKTPGYARWDIKVKFSNITSEWN
                     VEGKSRDKGNDLAEMTFGTSRVNAYKLIEDALNLKETKVFDQIINPDGSKTSVLNKKE
                     TMLAGQKQELLKEEFKNWIFNDQERRNRLVKLYNERFNSIRNREYDGSNLSFEGMNTE
                     IDLRPHQRNAIARSLYGGNTLLAHVVGSGKTFEMVASAMESKRLGMCSKSLFVVPNHL
                     TGQIGREFMQLYPSANIMVADKKDFEPKNRKRFIGKIATGEYDAVVIGHTQFEKIPMS
                     KEYQEKHIQDQINEIVNYVEEYKHDRNQNFTVKQLEKTKKKLETRLEKLNDDFKKDDV
                     ITFEELGVDMLFVDEAHNYKNLYLYTKMRNVAGIGQSEAFKSSDMFMKCRYMDEMTGG
                     KGIVFATGTPVSNSMTELYTMQRYLQYESLKKNHLEHFDSWASTFGETQSSFELSPEG
                     TGYRVKTRFSKFYNLPELMSMFKEVADIQTADMLNLPTPEANYEVIKTEPSEEQKEIL
                     KSLSERADDVRNRVVEPDVDNMLKITNDGKKLALDQRLINPLLPDNPDSKVNVCVKNV
                     FAIWDKTKENRSTQLLFSDMSTPKGDGEFNIYDDIREKLVAMGIPKEEIAFIHEANSD
                     KQKDELFAKVRKGEVRILMGSTQKMGAGTNVQNKLIALHDLDVPWRPADLEQRAGRIV
                     RQGNENEKVNIYRYVTENTFDAYLWQTIENKQKFISQIMTSKTPVRVAEDVDESSLNY
                     AEIKALATGDPKIKEKMDLDNEVTKLKMLEANYKSNRYRLEDKVAKNYPEEIARTEKL
                     IEAVKKDISNVEPKAEGEEKFTSITIAGEKITDKKLAGERLLEAISKVKINESKVIGK
                     YRNMDLEVSYNFFTNSHNFSLNGVAKHLGELGTSADGNITRLDNALEKMPEKLNMLEE
                     KLISTKEQLENAKEELKKPFEKADELKTKVLRLAELNKLLDMGEVEEKKNDNPLVEDV
                     KRAIIDFCNREYEENHSYDEFHTLYPDLKHIGIAYTNTPDERHGIQYELNLEEKTWTQ
                     YIDDTPIKTESFDYENKGENEALRNMKNEIELSTFSDLVYVDSEDLRVATGLDIDDEG
                     NFYDPFAKDLDNDGIPDRYDSDFKDSDYFESTYDVEDNLHSKEETTQKSDDKPSILGQ
                     IRAYQEESKTEEKQKIKEQEFLR"
     gene            complement(63348..64151)
                     /locus_tag="PC466_000056"
     CDS             complement(63348..64151)
                     /locus_tag="PC466_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004804477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KilA-N domain-containing protein"
                     /protein_id="HDF2767496.1"
                     /translation="MSKINVEGSEISIIAIDNRDYISLTDMVRNIENGSALIEKWLRN
                     KNTIEFLGIWEEMYNTNFNSPEFEGIKNEAGFNRFILSVKQWVEKTNSIGIVARAGRY
                     GGTYAHKDIAFEFASWVSPYFKLYLIKEFERLKEEEQKKLGWDIKRNLAKINYRIHTD
                     AIKNKLVPDKLSKEKINFIYASEADILNVSLFGITAKEWRDENPDLKGNIRDYADISQ
                     LVCLSNLENLNAVFINEGMSQSERLEKLNAIAIEQMKILSESESIKKLK"
     gene            complement(64236..65942)
                     /locus_tag="PC466_000057"
     CDS             complement(64236..65942)
                     /locus_tag="PC466_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000779853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
                     /protein_id="HDF2767497.1"
                     /translation="MKLVIAEKPSVAISIAKVIGANKKKDGYYEGNGYRVSWCVGHLI
                     QMANPDAYDEKYAKWNMADLPIIPSDYKYEVAKATKKQFNILKKLMNDKEVDTVINAC
                     DAGREGESIFRLVYNQVNCKKKMKRLWISSMEDSAIKEGFDNLTDGKDYDNLFESAQA
                     RAIADWLVGMNISRLYSCLYQQNYSVGRVQTPTLAMIVKRDDEIANYQKEKYYTVELS
                     MNGFTLSTDRIDDEVAAEQLISLVGDKIEITDVIQKEKITKPDLPFDLTTLQRECNKY
                     FGYSAKQTLDYTQSLYEKKLITYPRTDSRCLTEDMIVSTVNNILGKNDFDTERIKVVF
                     NSKKVTDHHAIIPTISSVKEDVSELPLSEAKVYFLISDKFHASVGYPLIENTTKIVAS
                     FDGFEFTSSGKVIKDEGFSKYLKEYKSKKSEDAVLPDVSVGDVLSVENKEVKEKFTQP
                     PKHFTEDTLLKSMEIAGNDALEKGVEVERKGLGTPATRAGIIENLIFKRFVERDKKNL
                     IATHKGISLVTIVADTFKSAETTAKWEMELSDIAQGKSSKKEFLDAIENEIKEAVLTY
                     RK"
     gene            complement(66037..67578)
                     /locus_tag="PC466_000058"
     CDS             complement(66037..67578)
                     /locus_tag="PC466_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4366 domain-containing protein"
                     /protein_id="HDF2767498.1"
                     /translation="MKTSLKKNNKFWTVALAVIVSISCILGLWTVVYAQEQKSEAPTK
                     NEAVQTEVEVNVRYIFEDEKVFKEEKIKAEKGQLIDSGDLPMLPDDMKFIDEFLFYEV
                     KGDGKDEIIRKVAKMEVKDKETQTEEEKPKQDECTQTEDKGTQTELSKDDISKIEKEA
                     KELQDKLDKLNCELKDKDKLSDKQKNKIKDLEDEIDSLKEKMKKDKGNKDLSEDMKKE
                     IDKLTEKVKELEKKATETNKAPVTSQSVTPISPISGIKTSSGISPQTPQTSVSSTGKG
                     SSDSVSSGNTTKDTGKGKTEVKEKEKEVRYPNKLTAKAPANNSQDSSMGSASKSVNTN
                     KGVASSPSKARASVTENKDNANKEYPIHHGDSSDNKETDQYSADARQFITFQTKNGKT
                     FHLIINHDEDSENVMLLTEVSEDDLLNMVEKKEAPKQEVVKEEPVKEEVKPEKKDEKS
                     NLGTYIILLLVVGGALGAGYYFKVVKKKEDKELEALEEEDDDFFSESESEEEINDADE
                     VEDEE"
     gene            complement(67553..67792)
                     /locus_tag="PC466_000059"
     CDS             complement(67553..67792)
                     /locus_tag="PC466_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HDF2767499.1"
                     /translation="MKKELTTVKNRIKKLKDKKALIDEELEPLFIREEELENEEIIAI
                     CRKNNITISDLIAKVNRQKAEMKKEKTNENQFEKE"
     gene            complement(67804..69936)
                     /locus_tag="PC466_000060"
     CDS             complement(67804..69936)
                     /locus_tag="PC466_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HDF2767500.1"
                     /translation="MGKKLKKDFKERHKASLEREMFHSKTDTIPEESKLKHNDDYRGK
                     IVHEKERFQDKVHEKTSKVSADNEKSYGTSKRNEKYRTSDKGDVNSAIETGRSDYITE
                     VKDGKIYDPLGKDLDNDGIIDRYDNDFRDSNYFESTYDVEDNLSHKEKSLENSFKNHK
                     TQKSRYKRKNYSESLYTRKKDDAPKGNKADDKKAGKDAVSGKVYSSLSKDQKKKLKKD
                     MVKVSALSGLAKGSETVRDYLSHGSDENQGVEAGEKTADTSSKLIHGIKKYSDKKRAK
                     RGYDLTNKDYKIRKRKSKLEFRDAKKELKKTDEYKRASAYKRFQKKNQVKAAISRENK
                     SRLRDRIKEGLIGTLKSSKDMIIRKAKGLMLIFIGIIILGTFVINFAGTGMTGFMNST
                     SSVLTTSYLSKPNVLSEINQKFSDMEGELQSEVDYVKENYPGYDEYILNNTEYIGHNV
                     HELLSYITSRCGEVKSVSEVESILKELFESMYDLEYREEIEIRYRTVTETYTDEDGNE
                     YTESHEEPYEYKKLIVTLHKKEMDSIIRKVFANYPDNLKHYEALFLAQGNMREAFGNS
                     DLISANGGIGGGKEYEASTEVQKKIVNAAYITPSPGAGWCAMWVSQVYQNAGLGYIGG
                     NACDMYRNYTFTSDRSKLKVGMLVAVESSSSGSSAGLTYGHVGIYIGDGKVIDNIGRI
                     RVTTLDDWIATFCKHHPVGFGFPPNVKK"
     gene            complement(69940..72369)
                     /locus_tag="PC466_000061"
     CDS             complement(69940..72369)
                     /locus_tag="PC466_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF2767501.1"
                     /translation="MNKKRKIQQIKLMQNEKALRSQKRDLKKSNCKSKKDKGGILDLI
                     FKKEPKRYTVEDTIPYLRLLKSGICQLDEKHFSKSIAFQDINYQLALDEDRDLIFNQF
                     ANFLNSFDPSISIEFSYINQLGRNEEMKSAIQIPDKKDGFDDIRFEFREMLKSQIVKG
                     NNGLKKSKYVTFTVEADNLEQATSKLERLEIDILSSLKSMGVRAESLNGEERLKILHD
                     VLNPNKTFKFSYKDLKKRESTKTYIVPDEFNFTPSRYFKFGKFIGATSHFQILASELS
                     DRMLSEFLDIDDNINISFHIRAIDQSEAIKMVKRKNTDIDKMKIEENKKAVRSGYDMD
                     ILPSDLITYGEDVKSLLKDLQTRDERMFVVSIVFMNFARTVQKLDNTIAQISSIANKH
                     NCKLKRLDHSQEQGLVSVLPLGVNKIEIDRGLTSSSTAVFMPFTTEELFINSSNSLYY
                     GLNALSHNLIMADRKKLKNPNGLILGTPGSGKSFSAKREMANAILVTDDDVIICDPEG
                     EYGNLVRQFKGEVIKVSSKSKDYLNPLDINMNYGDGDAPLKDKANFIMSMLELVVGGS
                     GLTAEEKSVIDRCLPKIYEKYFEHPTPDNMPILQDLYDMLKGQEEKVGKKLATEMEIY
                     VSGSLNVFNHRSNVDLNKKLLCFDIKELGSQLKKIGMLVIQDQVWNKVSQNRGNKATR
                     YYIDEFHLLLKDEQTASYSVEIWKRFRKWGGIPTGITQNVKDLLMSKEIENIFDNTDF
                     VLMLNQASGDREILARKLKISLPQLRYVTNSNEGEGLLFFGNTIVPFIDKFPKDTILY
                     QKMTTKPEEVR"
     gene            complement(72281..72670)
                     /locus_tag="PC466_000062"
     CDS             complement(72281..72670)
                     /locus_tag="PC466_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HDF2767502.1"
                     /translation="MAYVPIPKDLNRVKTKVAFNLTKRQLIGFTLAGLVGIPVYLFMR
                     KFVPNDIAVIFLIVSTLPIFFITLFEKDGLTFEKYFKYIYLHKFYQPQKRVRKEVYLE
                     QEKKNSANKTHAKRKGIEKSKAGLKEK"
     gene            complement(72674..72934)
                     /locus_tag="PC466_000063"
     CDS             complement(72674..72934)
                     /locus_tag="PC466_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HDF2767503.1"
                     /translation="MNKRKTVFIVVIGAGIMAIIDRIRLHNKVEELEEKTEDIGRCHN
                     DFYLIQQRYNKNTDEQLATIQEEIGSVYEHFEELSKGKEDGR"
     gene            complement(72952..73815)
                     /locus_tag="PC466_000064"
     CDS             complement(72952..73815)
                     /locus_tag="PC466_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2767504.1"
                     /translation="MFGIFDKIEEFFKELLLGGIQANLESMFLDINDKVGAVATDVGK
                     TPMGWNGDVFAFIKSINDSVIIPIAGLIITAVLCIELINMVMQKNNMHDTDTFEFFKY
                     IIKMWIAVWLVSHAFEFSMAVFDVAQHMVNKAAGVINTSAVISGDQIVKMVDGLKDKG
                     LGELVMILFETSLIKVAIQVISIVIMLVVYGRMFEIYVYSSISAIPFATMGNKEWGQI
                     GTNYIKGLFAIGLQGLFLMVCLGIYAVLVKTIQITDIHTSTFTILGYAVLLGLMMLKS
                     GTLAKSVLNAH"
     gene            complement(73835..74050)
                     /locus_tag="PC466_000065"
     CDS             complement(73835..74050)
                     /locus_tag="PC466_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002838961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Maff2 family protein"
                     /protein_id="HDF2767505.1"
                     /translation="MEFFAQAVNVLKILVMAVGAGLGAWGVINLMEGYGNDNPGAKSQ
                     GIKQLMAGGGIVLIGLKLIPLLANVLK"
     gene            complement(74054..74365)
                     /locus_tag="PC466_000066"
     CDS             complement(74054..74365)
                     /locus_tag="PC466_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HDF2767506.1"
                     /translation="MKQEMININANLVAEPTFSSFEKEGEEVEVVNFTLVKKYGKGKE
                     YINCAAYGEKAEKAEDFEKGDLIHVFGYFKKREKEGKTYKNFVVKSYNKIEKKEENEE
                     E"
     gene            complement(74529..74762)
                     /locus_tag="PC466_000067"
                     /pseudo
     CDS             complement(74529..74762)
                     /locus_tag="PC466_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565771.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraG"
     gene            74904..75077
                     /locus_tag="PC466_000068"
     CDS             74904..75077
                     /locus_tag="PC466_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002576203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2767507.1"
                     /translation="MDYMTLKEASEKWGVSSRQINYYCTDGRIPGAVKMAGVWLIPKE
                     AEKPKDRRYNESR"
     gene            75082..75792
                     /locus_tag="PC466_000069"
     CDS             75082..75792
                     /locus_tag="PC466_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002576202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2767508.1"
                     /translation="MLHIAICDDEKDFVQYLTDLLNQYSKETGRDIKITPYYDGMELI
                     EKYDPTIDLIFLDIQMKVVDGLHAAERIRQMDETVGIIFLTTLTQYGLEGYKYHATNY
                     IIKPMKYARLKSEMDKFLERSQKEDTPSLVITNDTGKYKVPLKSIRYVETYNRNLMFH
                     TEQENIICYKSMKEVERELCDKDFVRCHTSYIVNLFYVKGIKKLDIELITGEIIPISQ
                     PKRKEFMERLTDYWGDML"
     gene            complement(76063..76224)
                     /locus_tag="PC466_000070"
                     /pseudo
     CDS             complement(76063..76224)
                     /locus_tag="PC466_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569186.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            76835..77020
                     /locus_tag="PC466_000071"
     CDS             76835..77020
                     /locus_tag="PC466_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HDF2767509.1"
                     /translation="MLKKYWIKCPICNGKTRVQVFHNTVLKDFPLFCPKCKLTHIIDV
                     EKLEIVIKNTEKQTFII"
     gene            77037..78020
                     /locus_tag="PC466_000072"
     CDS             77037..78020
                     /locus_tag="PC466_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004607971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HDF2767510.1"
                     /translation="MKRLPKYTPAEVRNDPYGFTYKEMSEVIGENEAKALYEELYKQL
                     PRKKNLSMLVKNICKSSDTEKYVYELKDNKYIETVFIKRRDGGTVCVSTQVGCPVGCI
                     FCESGRNGFVRNLTSSEIVQQIILLRRKVNRIVFMGMGEPLFNYDNLIKAIHILRDRY
                     GLNFPTDGITISTVGPVDQLKKLREEHLKIQLTISLHAATQSARNRIIPHMRIYAIED
                     VVKQALSYSERHNRKIVFAYLLLPGINDRPSDVRQLAKWFRGKKVMINVLQYNPTSNS
                     RIKAPQKREIVAFKHQLEQAGLEVTMRVSHGREINAACGQLANTYNKFKKK"
     gene            78494..78931
                     /locus_tag="PC466_000073"
     CDS             78494..78931
                     /locus_tag="PC466_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003508282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDF2767511.1"
                     /translation="MELSSSDKERIQHQYDALAKKTLVGEAKSHRRTLAKRAAREVTF
                     SDLSESELAQLFTTDEYESDYFRFQVSGFDVLVKNELLAEALNALPERKRDIILLSYF
                     LDMSDAEIGELLNVVRTTVFRHRKSALAKIKQYLEGKADDEYR"
     gene            78915..79157
                     /locus_tag="PC466_000074"
     CDS             78915..79157
                     /locus_tag="PC466_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2767512.1"
                     /translation="MMNTVRKSENLLPFPVISAAANGDTTAMCAILKHYEGYIAKLCT
                     RTLKDDAGNTYSYVDEEMRNRLQVRLITRTLAFHVG"
     gene            79616..79789
                     /locus_tag="PC466_000075"
     CDS             79616..79789
                     /locus_tag="PC466_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002604472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposon-encoded TnpW family protein"
                     /protein_id="HDF2767513.1"
                     /translation="MDKKQTITTERKIGKITYLVQALPSEKATDTIHKKIEKLIVKDL
                     QKKPGNPGFLASE"
     gene            79867..81540
                     /locus_tag="PC466_000076"
     CDS             79867..81540
                     /locus_tag="PC466_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016289898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDF2767514.1"
                     /translation="MLQSNKITALYCRLSQEDMQAGESGSIQHQKMILQRYADEHHFL
                     NTKFFVDDGFSGVSFEREGLQAMLQEVEAGRVATVITKDLSRLGRNYLKTGELIEIVF
                     PENGVRYIAINDGVDTAREDNEFTPLRNWFNEFYARDTSKKIRAVKQAQAQKGERVNG
                     EYPYGYIPDPNNRHHLIPDPETAPIVKQVFAMFVSGVRMCEIQKWLAENKVLTIGALR
                     YQRTGQARYQRAMIAPYTWPDKTLYDILARQEYLGHTITAKTHKVSYKSKKTRKNEEE
                     QRYFFPNTHEPLVDEETFELAQKRIATRHRPTKAAEIDIFSGLLFCAGCRHKMYYQQG
                     VNIEPRKFSYSCGAWRNRARTGSECTSHYIRKNVLLDLVLEDMRRVLRYVKEHEQDFI
                     CKATEYGDMEARKALAQQQKELFKAQARMTELDTLFRKLYEDNALGRLTDERFVFLTS
                     GYVDEKKSLAARIDELQQQIATVTERKRDISRFIQIVGKYSDIQELTYENVHEFIDRI
                     LIHELDRETNTRKIEIHYSFVGQVDTEQEPTQVVNHDRRNMVDVKSIAI"
     gene            81564..82019
                     /locus_tag="PC466_000077"
     CDS             81564..82019
                     /locus_tag="PC466_000077"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2767515.1"
                     /translation="MKEYTLIIKGEMDFIILSPQVLSSLITQIHNSPERKVVVSIESI
                     MPPKFTDYLLRVINSNRFSNERFRYRYILENPVTKKGMYEILRQQLSRTNTERFPCFQ
                     TIQLTDTFQGNVELDMECNDLFFWACKDTAAKFVYTFPDGREETLVIEY"
     gene            complement(82067..83719)
                     /locus_tag="PC466_000078"
     CDS             complement(82067..83719)
                     /locus_tag="PC466_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008978103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDF2767516.1"
                     /translation="MSRKKQVYEKITALYCRISLDDGGDNESMSISNQKLMLRDFAEK
                     HGMFQYEYYVDDGYTGRNFNRPSFQRMIADIEAGKIGCVITKDLSRLGRNYIEAGSYI
                     EIFFPKHNVRYIAVTDGVDSLTRQEMDITPFKNILNDMYSRDISKKVLAGRMTRSRQG
                     KFCGGQPPLGLMRDPEDKGHLILDPETAPVIRKIYDMALDGWGCMRIAKQLMDDKIPI
                     TRVKSNTECDVNYYSWGSARISHILRNPFYKGAHLVCRTHQKGIRSNTYDIIPREDWE
                     VIEGCHEAIVTPEEWEQVQDIIDRRPTIMKGNACPFYNLFHGLVYCATCGKSMQVRYE
                     KVGRTGKNRFTGEMREPIDRAYYICQTYNRLGKNACTSHKIEARDLYNLVLKDIQELA
                     AQAMKDADAFYQRLSSRMERRYLVDASQTEKERKRLEDRNQEIDGMFLSLYTDKAKGV
                     LTEQRFMKLTAALEQEQEANQKRLHDLAVMQSRADAQESEVRTFIKEIRRYAAIAELD
                     ESVLNRLISKILIGEVKKVDGQKVQEVRIVYNFVGEIPEIAA"
     gene            complement(83792..83959)
                     /locus_tag="PC466_000079"
     CDS             complement(83792..83959)
                     /locus_tag="PC466_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008978104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2767517.1"
                     /translation="MEKSKNQKNKVRFVVVREFSGEKSMREAFEQLIERQTCEHFEEW
                     RHQREMAEKAA"
     gene            complement(84227..85585)
                     /locus_tag="PC466_000080"
     CDS             complement(84227..85585)
                     /locus_tag="PC466_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015559850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence-associated protein E"
                     /protein_id="HDF2767518.1"
                     /translation="MSAAEALAPEQSVDEVREGLSVTEKGQPANTIGNCRTVFSHDPL
                     LRDAIRLNLLTDRVDIVRDLGWRRNTSALTDTDVKYLLLYFEQNYGLTSEKKMTAALS
                     IVANENCYHPIQDVLNGLVWDGTPRIRSCLHHFLGAEVSDYVEEMLKHFLLGAIRRVF
                     SPGSKYEEMLCLVGGQGAGKSSFFRLLAIRDEWFSDDLKKLDDDRVFLKLQGHWIIEM
                     SEMLATSSAKSIEEIRSFISRQKETYRTPYEAQPKDRLRQCVFGGSSNTLDFLPLDRA
                     GNRRFLPIMIYPEKAEVHILEDEDASRAYLLQVWAEAMTIYRSGKYSMKFSKSIQRQL
                     VEVQKDFMPEDTEAGQIQGFLEHYTGSMVCSKQLFKEALGHTYDEPKRWQLHNINEIM
                     NTVVTGWKPFSNPRMFAGYGRQKGWERDVSGNELPGNEDGFVELSEEECRQLELPKEW
                     IA"
     gene            complement(85545..86231)
                     /locus_tag="PC466_000081"
     CDS             complement(85545..86231)
                     /locus_tag="PC466_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009261158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HDF2767519.1"
                     /translation="MKTGCLFLCLEVRKSNVFEAVKQAVPTRQAAESYGIQLGRNGMT
                     CCPFHDDKHPSMKVDRRFHCFGCQADGDVIDFTARLFGLNKKDAALKLAEDFSVGFDA
                     KGHDPPRRKPGKRKISEELRYRQAEQKCFRVLCDYLHLLERWEKEYAPQTPEEAWNPL
                     FVEALQKKPYTEYLLDILLSGSMEERACVVAEYGKEVRKIEQRISEFTASHPAGRHER
                     SRSFSAGAER"
     gene            complement(86247..87491)
                     /locus_tag="PC466_000082"
     CDS             complement(86247..87491)
                     /locus_tag="PC466_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002594256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/arginine repetitive matrix protein 2"
                     /protein_id="HDF2767520.1"
                     /translation="MKLTRHNGRSGKHGTYNPRHNDRRFDVENSEHIDAERARQNVYW
                     DCYRGFTTHEFRENPEQPDFSFEEIERMYYNEHYGGHVEAQNARNEKTRHTERNRTVE
                     DLLKNNKTCPEESIYQIGTMGESVPPDTLFSIVNEFYEEFERRFGSHIHILDWALHLD
                     EGTPHIHERHVFDCENRYGELCPQQEKALEELGIPLPNPEKPKGRNNNRKQTFDAVCR
                     TILFDIARRHGLHLDQEPSYGGRDYLEKQDYILMKQKEQLAAQEQKLEELTLKIEDVE
                     TLLDDVSDAAYDKAVEVVTDTVRQETHKEDIRLVEESKKWVLSPERKAPKKEREYAAE
                     RLDGVITKIKNAMQHALAKIQRTLMQPEVKQAGKEQVKKKAKESIMDILAKAKINADR
                     DNRERWEREGRIAPTKKNDIEL"
     gene            complement(87919..88224)
                     /locus_tag="PC466_000083"
     CDS             complement(87919..88224)
                     /locus_tag="PC466_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002594257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone"
                     /protein_id="HDF2767521.1"
                     /translation="MRKLSKYEKETIINWNEAENLASVYTFNASLKRRLADFSRKYPL
                     LCRLERSTPEGSVTYVLDKSRLSIRLVPPYSEERKAAASAYAKEHGFQVVGAEEKIA"
     gene            complement(88208..88501)
                     /locus_tag="PC466_000084"
     CDS             complement(88208..88501)
                     /locus_tag="PC466_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002594258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2767522.1"
                     /translation="MTLSMKEKKILYAYGCPSHHNTVTRLKWLTALTVDPEAKRRMLG
                     LARKVETEVGENWYEDFYHHLRMEMDEYRRLKRSLRVLKSYTDYEEDLYEEAV"
     gene            88867..89715
                     /locus_tag="PC466_000085"
     CDS             88867..89715
                     /locus_tag="PC466_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004845315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2767523.1"
                     /translation="MYAKLTIPERLKDLRVVDKHLTLEQLAEQTGLSKSALGKYETDD
                     YKDISPFAIATLADFYGVSTDYLMGLTENKNHPNIELQSLHLSDDMVELLSSGKINNR
                     LLCELATHPNFRRLMIDMEICIDQIANMRVEQMNLVLEATRQTVMNKYAPGEDDLYMR
                     TLELGQVQESDFYSHVMHDDLDSIVRDIREAHRKDKTTADPQPTLDDVKEKFEQAIGQ
                     GSDTEMLIHEFCDKLQIPFEKISSEDFSAFLRILSLSKQLKSSNNMRGKASPIPPNRK
                     ARRKRK"
     gene            complement(89837..90118)
                     /locus_tag="PC466_000086"
     CDS             complement(89837..90118)
                     /locus_tag="PC466_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015574404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2767524.1"
                     /translation="MILEEMYNGRFYPCETVVADSPRFKQAVKASAALMDTLSERLSK
                     EDYALVEELREQVAIAQCEENESHFKYGFSAGLLVQQEAHAQVSQKDKE"
     gene            complement(90132..90509)
                     /locus_tag="PC466_000087"
     CDS             complement(90132..90509)
                     /locus_tag="PC466_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009261160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TnpV protein"
                     /protein_id="HDF2767525.1"
                     /translation="MEHLPKKIHHNGISYTLVGDYYIPDLKLSEEIRPIGRWGRIHKA
                     FLQEHRPGQYNELLLSGKLWTYLADLNEQADDRLACIISQMQAAEGVTEELKARDQLA
                     WVGGMNSIRSRVEEIILSEMIFV"
     gene            complement(90607..92169)
                     /locus_tag="PC466_000088"
                     /pseudo
     CDS             complement(90607..92169)
                     /locus_tag="PC466_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565768.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
     gene            complement(92166..92651)
                     /locus_tag="PC466_000089"
     CDS             complement(92166..92651)
                     /locus_tag="PC466_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009346332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HDF2767526.1"
                     /translation="MINEEIARKTLNMEINAGKVTGKVLLNLLKKLMKEAEKFGGLEK
                     LVNANGNEVKLKDMVKKGQLEEIPVEEAELKELKKELNRYGVKFSVMKNKETGKNSVF
                     FQAKDMKVMDKAFKHALSKSEKKAERKESIHKNIEKFKEMAKNSISKEKIKNKQKEQS
                     L"
     gene            complement(92653..93675)
                     /locus_tag="PC466_000090"
     CDS             complement(92653..93675)
                     /locus_tag="PC466_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HDF2767527.1"
                     /translation="MYLFDEQPIVANKTLAREIGLNEALILQQINYWIEINKKSGKNY
                     HDGKYWTYNSIRAWQENDFDYMSFDTVKRTFSKLEKAGYLLVGNYNKDPRDKTKWYTI
                     NNDKLEELYMDMDLKKQKIQTEALKNSMPNALGQNAPMDKGKISQCNNADCTNAQVQN
                     ALMQKDNLHQPLPENTTNNTTNNTTNNSAYISIHPSIKEKNQLFSENMKGGRIDISYK
                     NIYQNCLEELRHQTGYYEHMSIGNKSVAEEFDEILKILADVMVLDDESFITINQTKIS
                     VQVVKERFRKLNSGHLEYLVGVLRENEYRIRNIRAFVLTAAYNAPSGIDAYYSALVSY
                     DMRGGY"
     gene            complement(93761..94042)
                     /locus_tag="PC466_000091"
     CDS             complement(93761..94042)
                     /locus_tag="PC466_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2767528.1"
                     /translation="MRWILKIILFPISIALSILIAFLSFLLGIGTAILYLLMMFCIFG
                     AIASFLQKEVTIGIEALILGFLLSPYGIPMVGTAVIAVLTGVKEAIRSI"
     gene            complement(94061..95695)
                     /gene="rlmD"
                     /locus_tag="PC466_000092"
     CDS             complement(94061..95695)
                     /gene="rlmD"
                     /locus_tag="PC466_000092"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HDF2767529.1"
                     /translation="MLSKNEMYIVDIVDIGQGGVGVGKYNGITVFVEGGLIHDKVKVR
                     INKVKKNYAEGDIVEIIEKSPFRVKRVCSDNLRDCGGCQIQDLDYNKQLEMKTNEVKQ
                     VLSRIGKLEDVEVHDTIGMDNPYRYRNKAQFPIQKNNGIPIIGFYKKKTHDVISTEKC
                     VIQHEINDKIVKIIKTYIRAYKVSIYDEKTHTGLIRHLVTKIGFTTKEVMVVLVANGN
                     KLPYLKELASVLKENIPGFKTLVVNVNQKDTNAILGRENIVIYGDGKINDYIGDLVFE
                     ISPLSFFQVNPVQTKVLYDKALEYANLNDTDTVFDIYCGIGTISLFLAQKAKKVYGIE
                     IIDDAIKDAKINAKLNNIHNAEFYVGKAEEIVPKMYREGKTANVVVVDPPRKGCDEKV
                     LETIVSMNPERIVYVSCNPSTLARDLDYLNVHGFKCVEAQPVDMFPHSTHVETVALLS
                     KLDVDKHIDVEIKLDELDLTSAESKATYAQIKEYVLEKFGLKVSTLYIAQIKKKCGIE
                     LREHYNKSKKDNQAIPQCTPEKEEAIMDALRHFKMI"
     gene            complement(95870..97630)
                     /gene="pyk"
                     /locus_tag="PC466_000093"
     CDS             complement(95870..97630)
                     /gene="pyk"
                     /locus_tag="PC466_000093"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HDF2767530.1"
                     /translation="MLNNVKKTKIVCTLGPASQSEEILTQLMQNGLNVCRFNFSHGSH
                     EEHKERIDMAKKVREKLNKPVAILLDTKGPEIRTGNFEDPEVFLEEGQKFTITMKDIM
                     GTKEMCTVSYKGLAEDVKSGDSILIDDGLVGLRVKEINGEDIVCVVENSGIVKNHKGV
                     NVPGVKINLPAITPKDISDIEFGISQGIDYIAASFVRKASDVLAIREVLENNNATDIQ
                     IISKIENQEGVENLDEILKVSDGIMVARGDLGVEIPTEEMPIVQKMMIKKCNELAKPV
                     VTATQMLDSMIRNPRPTRAEVTDVANAIYDGTDAIMLSGETAAGKYPVEAVKMMATIA
                     KRTEETLDYDRLLKENGTNNVTVTDAISHATCTTAVDLNASAIITSTSSGYTARMVSK
                     FRPKSPIIATTNNEKTMNKLALTWGVYPVKSSVAGNTDEVIEKAIEAARQADYIDNGE
                     LVVITAGVPVGVSGTTNLIKVHVISEEIVQGIGVGTQTVEGKVRIIKNGNACVDFNEG
                     DILVSTATDAEMNNYIEKAGAVVTENGGMTSHTAIVGINLDIPVIVSATDITNLVKDG
                     EVVTVDASRGVVYRGSTRVL"
     gene            complement(97682..98641)
                     /gene="pfkA"
                     /locus_tag="PC466_000094"
     CDS             complement(97682..98641)
                     /gene="pfkA"
                     /locus_tag="PC466_000094"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HDF2767531.1"
                     /translation="MKTIGLLTSGGDAPGMNAAIRAVVRSAIYYGCKVYGINRGYKGL
                     LEEDLTEMNLSSVGDIIHRGGTILKSSRCEEFKTEEGRLKAVKILKKYKIDCLVVIGG
                     DGSFAGAQKLSDLGFPAIGIPGTIDNDLAYTDYTIGFDTAMNTIIDAIGKIRDTSSSH
                     ERVNIVEVMGRHCGDLALYAGLAGGAETIIVPEVEITVDEVALRLKTTQKRGKRHSII
                     VLAEGVGSASDLEKELKKESGADLRVTVLGHVQRGGSPTVSDRILASRLGVRAVELLL
                     DGKSARVVGIKENKIIDLEISEALAQKKVFDKEAYEMAKILSI"
     gene            complement(98850..102419)
                     /locus_tag="PC466_000095"
     CDS             complement(98850..102419)
                     /locus_tag="PC466_000095"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HDF2767532.1"
                     /translation="MNKDFAHLHVHTEYSLLDGFSRVKKLIKRAKELNMSSIAITDHG
                     CMFGVIDFYKTAIKEGIKPIIGCEVYTAARGLRDKDPNYDKYQGHLVLLAKNMEGYKN
                     LIKIVSTSYVEGFYYKPRVDMEELKKHNKGIIALSACLAGDVARALMNRNYEKAKQFA
                     LDYRDIFGEENFFLEIQDHNLPEQKEVNSGLVKLSKETGIPLVATNDVHYVNKEDSKI
                     HDVLMCIQMGKTLNDPNRMRFGSDEFYLKSREEMEELFPYALEAIDNTVKIADMCNVE
                     FDFNTIHLPKYDVPEGYTPETYLRELCFNGLKERYDNPSNEILERLNYELDVIEKMGY
                     VEYFLIVWDFINFSKENNIIVGPGRGSAAGSIVAYTLKITDIDPIKYSLLFERFLNPE
                     RISMPDIDIDFCYERREEVIDYVKRKYGDDHVAQIITFGTMGAKAAIRDVGRVLDIGY
                     NKVDKVAKEIPFALGMTIDKALDTNPNLKELYDQDPETKEIINISKQIEGMLRHASTH
                     AAGVVISKNPVDEYVPLYKHQDAITTQFTMTTLEELGLLKMDFLGLRTLTVIRDTLDL
                     IEKNRVIKNYTEKIDFSKMDYDDPKVYEMLSSGNTLGVFQLESAGMRSFMKQLKPDNF
                     EDIVAGISLFRPGPMDSIPAYIKNKSNPKDVTYLHEKLKPIMEVTYGCLVYQEQVMQV
                     VRDLGGYSYGRSDLVRRAMSKKKMDVMEEERQYFIHGKFDEDGNIEIAGCIRNGVEEE
                     IANKIFDDMIDFARYAFNKSHAAAYGVLAYETAYLKTYYPVEFMAALITSVMGNTDKV
                     VEYIRECKALEIDVLPPDINKSFSKFSVEGDNIRFGLAAVKNVGVNIINNIIAERESN
                     GLFVDLVDLVKRLDQKDTNKRVIESLIKCGAFDNISENRASLMAGYESLLESVSMDRK
                     KNVQGQISLFDAFGDSEEDSDFQQIYSLPKRQEYEERERLNLEKEVLGMYVSGHPLSQ
                     FEKELQEKTSMDNGKLNSLKEEEESYLQMNETDVIMGGMIVTKTIKTTKRNEIMAFIE
                     LEDLYGAIEIIVFPQLLQKYNVILNEDNIIYVKGTLSIKEGENAKLIAREIKDINDDT
                     DFADRNYNSGRTRNVENIKPESGKKLYLKIDSMSDTDTTNNIVEIAKQYPGNDSIYLY
                     PMDENINGKRKAYKMTGALTCICDEFINNLEELLPKDNIKVKA"
     gene            complement(102576..103523)
                     /gene="whiA"
                     /locus_tag="PC466_000096"
     CDS             complement(102576..103523)
                     /gene="whiA"
                     /locus_tag="PC466_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HDF2767533.1"
                     /translation="MSFSTETKNELARVISGNECCNIAELSALVKSGGSIQIVGYKKL
                     NLKITTELNSIARKVFKLLKKNFNINTTISVNKNQMLKRNNSYVLMVTSEMGSEMLLK
                     KLGILEDKEGFFTINKISENLIKHEGCKRAFIRGAFLGGGSISDPEKNYHMEFVTNNE
                     EFADSLKELINSLGFNSKIVARKNNHVVYIKESEQISDLLSIIGGHHALLSLQNTKIV
                     KEMRNNVNRIVNCETANLSKTVNAAVRQVENIKLIQETIGISSLPENLQEIAKIRIEY
                     EDMTLKELGEMLEPPIGKSGVNHRLRKIEEIATDLKKKS"
     gene            complement(103540..103965)
                     /locus_tag="PC466_000097"
     CDS             complement(103540..103965)
                     /locus_tag="PC466_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HDF2767534.1"
                     /translation="MREEVSAGGVVLFGNTILLLRKFNGDWVLPKGKVEEGENNQEAA
                     LREVSEETGVKADILKYLGEIHYTFKENWDENRAVHKTVFWYLMQAKNMDTIPQKEEG
                     FIDAKFIHLDRVVDLARYDDEKEIIKVALQEIKKRLKKN"
     gene            complement(104034..105140)
                     /locus_tag="PC466_000098"
     CDS             complement(104034..105140)
                     /locus_tag="PC466_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HDF2767535.1"
                     /translation="MAKLLIIVGILGWIALIVSLFIYKKAKNEKVKLFQRSIVENREP
                     NVVVIGGGTGQSVFLRGLKHTTQNITAIVTVADDGGGSGVLREDLGMLPPGDIRNCLL
                     ALANIEPTMNEVMQYRFTEGLLKGQSFGNLFLAAMNGLYGNFEKAVYKLSEIFAITGR
                     VLPVTLEDVNLVAKLENGNIINGESSIPEESKIQKSSIDKIFLNPKDVKPLKDVIASI
                     YDADIIIMGPGSLYTSIIPNLLVEGIVDAIKSSVAPKVYIANIMTQPGETEGYNVLEH
                     VNAIVKHTDENLIDYVIANNEILPEEMLDLYKQDGAEQVLLDKKQKDKLKEMGIKTVE
                     KNLIEIKNNYIRHDAKYISNIVIELALNHNYNKS"
     gene            complement(105152..106009)
                     /gene="rapZ"
                     /locus_tag="PC466_000099"
     CDS             complement(105152..106009)
                     /gene="rapZ"
                     /locus_tag="PC466_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HDF2767536.1"
                     /translation="MKFVIVTGLSGSGKSETMRALEDMGFYCVDNLPPALITKFAELC
                     YQPNSSIDKVALGIDIRGRKFFEALHESLNYLEKENYEYEMVYLDCNDDVLLKRYKMT
                     RRNHPLAKDMQIPEGIKMERKIMEPLKELSTCIIDTTNMKPKDLKEEIKKIYSSGEDN
                     PNLTISVVSFGFKHGILADADLVFDVRFLPNPYYVEELRAKTGDDKEVRDYVMNSKIS
                     EEFYVKLLDMIHFLVPQYIDEGKQHLVIGVGCTGGRHRSVTITNLIAEDLSNKGYRVV
                     KKHRDSMLR"
     gene            complement(106040..106753)
                     /locus_tag="PC466_000100"
     CDS             complement(106040..106753)
                     /locus_tag="PC466_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HDF2767537.1"
                     /translation="MKILADYHTHTLYSHGKGTIEDNVKVAISKGIKTIGISDHSYKH
                     IAYGVKKKDILKMREEVDYLNDKYNDINILLGMECNILDDKGNIDMDDKFIRDFDYIM
                     AGYHFGSTPTSLRSLLNHCNNYIFKTEKAKEYNTKAVINAISNNDIFIITHPGDKGDV
                     YIEEVAKTAKKTNTRLEINSSHSFLNVNQLNKIKGLENKFIIGSDAHCPERVGDFKLA
                     MKTISDSNLDISLVENIII"
     gene            complement(106757..107671)
                     /gene="murB"
                     /locus_tag="PC466_000101"
     CDS             complement(106757..107671)
                     /gene="murB"
                     /locus_tag="PC466_000101"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HDF2767538.1"
                     /translation="MNNQDIYINLLNILSKEDIKVDEPMKKHISFRVGGPADILVRPR
                     TEEQLKNVLKLVKEESIPYLIIGNGSNILIKDGGIRGVVIELADNFNSYEINDTRMTA
                     QSGALLSVLGKALQKQELKGFEFASGIPGTLGGALAMNAGAYGGEMKDIVKSVRLMDM
                     EGNIFELSNEQMEFGYRKSIISKNGYIALSAELELQEGNYDEIKSLMDDLATRRITKQ
                     PLNFASAGSTFKRPTGYFAGKLIEETGLRGLTLRGAQVSEKHCGFVVNQGEASAKDIL
                     DLIYVIKSAVYAKFGVMLEEEVKILGED"
     gene            complement(107944..108714)
                     /locus_tag="PC466_000102"
     CDS             complement(107944..108714)
                     /locus_tag="PC466_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HDF2767539.1"
                     /translation="MSKGFLTPGETAQATISAGIKKANISTQNAILLGLFGGAFIGFG
                     ALGSMIVSQTFGKIDPGVASFLSAMVFPVGLMLVVVAGAELFTGNTLMAIALMDKKIT
                     LGKMLRNWGLVYFANLVGSILLVALVFYSSTLTGDAATKAIAVAEAKVNSTIASMFLK
                     AILCNILVVLAVWMATASQDIMSKLASCWTVIMLFVLCGFQHSVANMFFIPMGMALGA
                     NITMVQFITNLVFVTLGNIVGGSIVVGGIYYLCYVKNS"
     gene            109032..110513
                     /gene="cls"
                     /locus_tag="PC466_000103"
     CDS             109032..110513
                     /gene="cls"
                     /locus_tag="PC466_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HDF2767540.1"
                     /translation="MFDISFFEMSIYEIAVTTIYIINFMVILNLIFREKRNINTTLTW
                     LLILVLIPALGFILYIAFGRNISKNNMFRLKEKDDKIIKSNILDTQVKLQSTSEIDSD
                     IHQHKDMIYALANSNNAHYTNNNDVWIYAESSQFFNSLLEELKKAKKYINIQFYIFKD
                     DKIGTEIIDILIDKAKEGVEVRLLFDAVGGRTLKNSTLSRLKESGVKVGSFFPSFLKI
                     VNFNLNYRNHRKIVVIDGKVGFVGGYNVGDEYLGRNPKFGLWRDTHTKLTGDCVIDLN
                     MRFILDWRYTTKEDLDLEKYFIEEDTNSNHPSENIGIQIVSSGPDISELDEIKYGYLK
                     MIQKARKYIYIQSPYLILDSTFIDTLKIACLSGVDVRVMIPSKPDHPFVYWASYSYAG
                     ELLKFGAKIYTYGQNAFLHAKTIVIDDSICSIGTANMDIRSFELNFEVNAFMYSSKKA
                     LEQRIIFENDILNSKEITLDIYNSRSTYIKIKESISRLLSAVL"
     gene            110831..111328
                     /locus_tag="PC466_000104"
     CDS             110831..111328
                     /locus_tag="PC466_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase subunit E"
                     /protein_id="HDF2767541.1"
                     /translation="MCDFISHNKQLFDELDIFIDSLTTKEGALIQVLHEAQGIFGYLP
                     KEVQLHVARKLGVAPAKVYGVVTFYSYFTTEPVGKYKISVCLGTVCFVKGADKILSAF
                     EKQLGIKVGETTSDFKFSLEGLRCLGACGLAPVVTVNGKVYGKVKPDQVSEILDTYRE
                     LELNC"
     gene            111345..113231
                     /locus_tag="PC466_000105"
     CDS             111345..113231
                     /locus_tag="PC466_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoF"
                     /protein_id="HDF2767542.1"
                     /translation="MRKVNSFDELKVLADELKPNLSLRKNYSKENVLRRELLVCCDTG
                     CTSSNSLEIVSELENEIKKSGIQDKVSVRLTGCFGFCAQGPIVKVYPDNVFYVKVEPS
                     DAEKIVQSHLIRNTVVEELLYEEESLSKKVEEQEEMSFYKKQLRIALKNCGLIDPDSI
                     EEYIANDGYLALGKCLTSLTPQEVIAEVKTSGLRGRGGAGFPTGSKWEAASKNPAGPT
                     DKKFVVCNADEGDPGAFMDRSVLEGDPHSVLEAMAICGYAIGSDTGYIYIRAEYPKSI
                     ERLKVAIAQAEKYGLLGENILGTGFNFKLELKYGAGAFVCGEGTALMHSIEGRRGEPR
                     MKTYSSSKSGLWKSPTCLNNVETFANIPAIILKGGDWFANLGTEDSSGTKVFALGGKV
                     ENVGLVEVPMGTTLRDIVFEIGGGIPEGKKFKAVQTGGPSGGCIPTEHLDTPIDFGSL
                     SSIGSMMGSGGMLVLDESDCMVDIAKFFLEFTVEESCGKCTPCRIGTTRLLEILTKIT
                     EGNGTLQDLDDLENLAETIQTASLCGLGKAAPNPVLSTLQYFKDEYIAHVVDKKCPAG
                     KCQNLLSYFITDDCKGCTKCSRVCPAGCITGSVKEQHTIDTSKCLKCGACIDNCTFNA
                     IIKK"
     gene            113254..115035
                     /locus_tag="PC466_000106"
     CDS             113254..115035
                     /locus_tag="PC466_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron hydrogenase small subunit"
                     /protein_id="HDF2767543.1"
                     /translation="MSLVNLTINGKHVSAPSGTSILDAAKLINIKIHNLCHLHMNEID
                     KLDTCASCRICMVETERGLVPACGTVIKEGMKVQTNSAKALNARRTIVELLLSDHPQD
                     CFVCEKNGDCELQTIAADLGVRKIRYQGSKSFAGKDTSTKSLVKDHSKCILCRRCETV
                     CNDIQTVGALSGVNRGFNTLVSTFFNSDMVETECTFCGQCISVCPTGALTEVDNVPKL
                     WDVLNKKEKTIVVQVAPAVRVAIGEEFGLEPGSISTGKMVAALKALGFEHVFDTNFGA
                     DFTIMEEATEFIERIQKGENLPILTSCCPAWVNFLEHNYPDKLNLASSCKSPQGMFGS
                     IAKNYYAPKILGINPEELYVVSVMPCVAKKYEASREELSESGILDVDLSITTRELAKM
                     IKEAAIDLPNLQDQDFDNPLGKSTGAASIFGASGGVLEAALRTSYEKITNKTLDNVNF
                     TNVRGLKGIREASIDVDGTTVNVCIVNTLKNARKIMDKVRSGECKYHIIEVMACPGGC
                     VGGAGQPYHHGNTEIVDRRANALYEIDRNKAIRKSHENPDLQAIYKDFFGEPNSDVAH
                     KYLHTHYFDKSCVYGECPQECACEEAK"
     gene            complement(115175..116971)
                     /locus_tag="PC466_000107"
     CDS             complement(115175..116971)
                     /locus_tag="PC466_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate oxidoreductase"
                     /protein_id="HDF2767544.1"
                     /translation="MGIEYFSKLLESSTEKELLLSKKSNNISTARLISFLIVIAGFAI
                     GFYNKNIVGIFVGVLSIIIFIALLVIHSKVKEEETYFKSKSEVLNKYIKRFGDGWKEF
                     KIDGKEYLKDENSQAKDLDLFGRASLYQYICVANTSYGKNFLAKYLWNENPDENVILE
                     RQRAIKELLSKDDFSIHIQILSNIIGKEQKNNSDSSIESFIEYGENKNVYIPKWMHIF
                     TWGLPTATILSFIFCMLGFLPVLPVFLLFIIQLGFSGFGYPRLMQTLSPLFSFSRSIQ
                     VYEKMFEVLEKETFESAYLKELQDKLSKGSGVSRGVKQLNSIGNAVNLRYNQILYIIA
                     CGVLMWNYHCAEALERWKGIYGNQIRDWFESIGEFEALISLTVISHVKENTCFPVIKY
                     EDTPRLKVEEVYHPLIAEKSVIANSIQLNSQTCIITGSNMSGKTTFLRSIGVNLVLAY
                     AGAPVCAKSFDATCMAIFTSMRIQDDVSQGISTFYAEILRIKSMIQYSLKELPMLVLV
                     DEIFKGTNSADRIIGASEAVKKLSKPWVISMVTTHDFELCDLSGSGDVEVVNYHFSEY
                     YVDDKIHFDYKIKDGRCKTTNAKQLMRMAGIL"
     gene            complement(117185..118114)
                     /locus_tag="PC466_000108"
     CDS             complement(117185..118114)
                     /locus_tag="PC466_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HDF2767545.1"
                     /translation="METSNKVSIREIIKELKLKVVYMPDDVDYYVYSQDINRPGLQFA
                     GYFDYFAYERIQIVGKTEYNFFGLMDSHIREEVLDRFFSYEIPALIISRDLEIKPDVI
                     EKAKKYKRILLSTNRNTTRLINRLSNYLDNKLAPHTTIHGVLVDIYGIGVLIKGESSI
                     GKSETALELIQRGNRLVADDAVEIRKLDESMLVGQSPELIRHFLEIRGIGIIDVRSLY
                     GVGAIKNSKMIDLVVHLEAWDETKYYDRLGLDKEYEEILGVNVEKLVVPVKPGRNTAM
                     ILEVAAMNFRQRGMGYDAAQEFTKKLSKLIDTK"
     gene            complement(118114..119931)
                     /gene="uvrC"
                     /locus_tag="PC466_000109"
     CDS             complement(118114..119931)
                     /gene="uvrC"
                     /locus_tag="PC466_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HDF2767546.1"
                     /translation="MFDIQEHLKKLPSEPGVYLMKDKYDHIIYVGKAISLKNRVRQYF
                     QSSKNHTSKVKSMVKNIYKFEYIITDSELEALILECNLIKRYRPKYNVVLRDDKTYPY
                     IKVTTNEDYPRILKVRRVLKDKAKYFGPYTNITAVNDTLELISSTYPIRSCKIDIDKA
                     IKNKTRPCLNLHINKCLGPCTGNVSKEEYGKMIEEIIMCLSGKEEKLMELLKEKMNES
                     SMNFRFEEAAVYRDKIKSLEEMIQKQKIDATVSDLNQDVVAMARAHNEACVQVFFIRN
                     GKIVGREHFILEGVMDSPRASILSSFVKQFYNEQEYIPKELIIEDEIEDSSILEEWLS
                     SKKGQKVTIRVPQKGEKKSLVEMVRKNAVEYLEKFSDMNKRKYEKSIGALEELKQILN
                     LEKLPIRIEAYDISNIQGVDSIGSMVVYTNAKKDKKEYRRYKIKTVIGPNDYDSMAEI
                     VDRRLKHGNLPDLILLDGGKGQVSAVKKVLELNDVDIPLWGMYKDDKHRTKGLICKEK
                     EIELDKTTNLYRFIASIQEEVHNYAITYHRSLRNKALTKSILDDIQGIGEKRKKSLLN
                     HFKDVEAIKKATMEELLEVDGMNKSIADNVYNFFRKEEN"
     gene            complement(120190..123015)
                     /gene="uvrA"
                     /locus_tag="PC466_000110"
     CDS             complement(120190..123015)
                     /gene="uvrA"
                     /locus_tag="PC466_000110"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HDF2767547.1"
                     /translation="MEDKIIIRGAKEHNLKNIDLELPRDKFIVFTGLSGSGKSSLAFD
                     TIYAEGQRRYVESLSAYARQFLGQMEKPNVEYIEGLSPAISIDQKTTSKNPRSTVGTV
                     TEIYDYLRLLFARVGDVYCPTCGEKISQMTIQEIVDKMLDFPDRTKLQILSPIVRGQK
                     GTHKKVFDNIKKEGFVRVRVNGENYEVSDDIILNKNQKHNIEVVVDRIVIKDGIESRL
                     ADSIETAVKLSDGLVIAQIIDGEEILFSTKFACPEHGIGIEELSPRMFSFNAPFGACD
                     VCNGLGESKEVDPELVVPNKDLSIKQGAVAAWGSTGVNDDTYYSKMIKSLAEHFNVSL
                     TTPFKDLPDDFVEELLYGKDNIIVEFTYESKFGGTRNYKSYFEGVIVNLERRYRETNS
                     DYMRDKIEEYMAERPCPKCKGMRLKKEVLSVLVDGKNIMEVTNLSVNELIDFMENINL
                     TEKQRFIAHEIIKEIKGRAMFLRDVGLDYLNLSRKAGTLSGGEAQRIRLATQIGSALV
                     GVLYVLDEPSIGLHQRDNDRLITTLRHLTDLGNTLIVVEHDEDTMREADYVIDIGPGA
                     GIHGGEIVAQGTLDEIIENENSITGQYLSGKKQILLPETTREGNGSFIEIVKASENNL
                     KNIDVKFPLGKFTCITGVSGSGKSTLINDILYKGVASKVNRLKQRAGKHKEIKGIESI
                     DKVINIDQSPIGRTPRSNPATYTGVFDFIRDIFASTNEAKARGYKKGRFSFNVKGGRC
                     EACKGDGIIKIEMHFLPDVYVPCEICKGERYNRETLQVKYKDKTISDILDMNVEEAVE
                     FFENIPNIKRKLETLMDVGLSYIKLGQPSTQLSGGEAQRIKLAAELSKRPTGKTLYIL
                     DEPTTGLHMADVDKLIQVLQRLADTGNTIIVIEHNLDVIKTCDYVIDLGPEGGDKGGT
                     IVATGTPKEVSKVDGSYTGQFLKKYFS"
     gene            complement(123034..125004)
                     /gene="uvrB"
                     /locus_tag="PC466_000111"
     CDS             complement(123034..125004)
                     /gene="uvrB"
                     /locus_tag="PC466_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HDF2767548.1"
                     /translation="MDFKIKSDFKPTGDQPEAIKSIVDSINRNEKFSTLLGVTGSGKT
                     FTMANIIQQVKKPTLIMAHNKTLAAQLYSEFKEFFPDNAVEYFVSYYDYYQPEAYVAH
                     SDTYIEKDASINDEIDKLRHSATASILERRDTIIISSVSCIYGLGDPKDYKELMLSIR
                     PGMQRDRDDVIKRLIEIQYERNDINFTRGTFRVRGDILEIFPASNDEKAIRIEFFGDE
                     VDRITEIDYVTGKIVGTRNHVVIFPASHYVTTPERIEKAIVEIENELQEQIKFFKEND
                     RLLEAQRIEQRTKYDIEMLKEIGFCQGIENYSRHITGRSEGERPYTLMDFFPDDYLII
                     VDEAHVTIPQVRGMYAGDRSRKTSLIENGFRLPSALDNRPLNFQEFEGNINQMLFVSA
                     TPGPYEIQHSETIAEQIIRPTGLLDPIVEVRPINNQIDDLVGEITKTIEKNERVLITT
                     LTKKMSEDLTNYLKEIGIKVKYLHSDIVTLERTEIIRDLRLGKFDVLVGINLLREGLD
                     IPEVSLIAILDADKEGFLRSETALIQTIGRAARNENGRVIMYADRITDSMQNAIDETK
                     RRRDIQNLYNEEHNIIPKTIQKNIRDSIEATKVAEEEVVYGISDTDDKDEIRANIDKL
                     KSEMMEAAQNLQFERAAELRDKVKQLEEKLEK"
     gene            complement(125191..126453)
                     /locus_tag="PC466_000112"
     CDS             complement(125191..126453)
                     /locus_tag="PC466_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase family protein"
                     /protein_id="HDF2767549.1"
                     /translation="MTKVIVLSVDSLFEKDLEFVKNLPNFKSILENCSIVKNINCVYP
                     TLTYPCHTSMVTGVYPKKHGIYHNEKFDPNKENKDWYWYSKDIKVKTIIDVAKENNLT
                     TSSVLWPVMGANPNIDYNIAEIWAPSREDDPRETFERSSSKVIMDGIYNRHCHYIDWK
                     LEPNMDLFGVNCSVDIIKEYKPDLMLIHLATLDHTRHNYGLFNDEVDKALKMNDKWLG
                     DIIQATKDAGTYKDTNFIILGDHGHLRVDKVINPNVLLKSNGFIKVENGEVKDFDAYV
                     NSSGISAQIIVNNLDRLTELRELLEEFKEELFIENIFTKEEASNLGLEGDFEMVIEGL
                     EGISFGNDFEGSIIKDSDIKDYKFAVATHGHLPTKGNRPPFIAFGPNIKGGVVIEEGD
                     LRAHAATILKMFDLKLDGVEKEAFDFIM"
     gene            complement(126516..127820)
                     /locus_tag="PC466_000113"
     CDS             complement(126516..127820)
                     /locus_tag="PC466_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF2767550.1"
                     /translation="MKLKRKLATGLAITLLLGSLVGCSNSNDANASKGEKTDSNITKI
                     DFWAPLGGTNGETAQKMVDQFNSEHKDVQVNMLKQKDYYENATKLQAALTSKDQPDVT
                     LLEITQTGTFASAGALVDMSKYFDKTYQERFFSGLLTNSYYEDKFVGMPFNRSTPILY
                     INRDMATKAGLDPSGPKSWEELKDYASKMTNKSEDTYGFETPIDIWFYEAMVMQSGGE
                     ITNGKKVAFNNEAGQAPVKFWQDMMKAGIMKMPPGEDYNAWDVAKQDFVNGKVGMIFT
                     STADLAGLMQQTEGKFEISTAFLPKNQKYATPTGGANLVMLEGGTDKEKEASAEFIEW
                     MTQTDKIVQFSSSTGYLPTTEDATNSEKLQTLYKEKPQYKVATDQLQYAVALPMLNGY
                     KEATDKLMDEIKKGLTDLNANPKDVVSKGTSAMQAVIDKTNK"
     gene            complement(127851..128711)
                     /locus_tag="PC466_000114"
     CDS             complement(127851..128711)
                     /locus_tag="PC466_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HDF2767551.1"
                     /translation="MDIIQPIKKDKVDIKKIASKSMEILILLLLSAIFIFPFIWMLST
                     SFKNPQEMMQLPPTIIPNDIVLENYSTAWHSGPFFRYLLNSVFVTGSVLILQFLVMVP
                     AAYAFSKIKFKGEKMLFGLLLVGLMIPPQVTFLPVYMMMSKFGFINTYIPLIIPFMTS
                     SFGIFLLRQNFMQISDETIEAAKLDNASDLKIMFRIMVPMAKPAVITFILFNFIYHWN
                     NYFWPLVMTNTDAIRTLPIGVALLKSSEGITAWNVIMAGNIILILPIILVYIFANKKV
                     KEAFMYSGIK"
     gene            complement(128755..129624)
                     /locus_tag="PC466_000115"
     CDS             complement(128755..129624)
                     /locus_tag="PC466_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDF2767552.1"
                     /translation="MKKQFNKAYLYITPAIIGTLLFIVYPIIKTISLSFKSGSLLSST
                     FENVGLNNYTELLKNPEFIQTITNTAIYTFFMVTISISLAIVLAVWLNKNSIIHNLTQ
                     SIIFTPHVISLVSVAVLWLWIMEPQYGFLNWILSTLHLPTSKWLSSESSALMSLILIG
                     IWKTLGYNILIVLSGLKSIPNYIYEASKLDNANKITNFFKVTLPLLSPTIFFLMITTT
                     TASFQVFDEISIMTQGGPVGSTNMLSYYIYESGFIYYDIGQASAASMFLLAIVMIATY
                     ANFRLLSKKVHYQ"
     gene            complement(129608..130678)
                     /locus_tag="PC466_000116"
     CDS             complement(129608..130678)
                     /locus_tag="PC466_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2767553.1"
                     /translation="MADIRLENVTKSYNKKNTVIENLNLTIEDGSFTVLVGPSGCGKS
                     TTLRMIAGLEDITSGKLKIEENDVTKTDASKRDIAMVFQNYALYPHMTVRENIEFGLK
                     NKKVEKEKREKLITEVIDVVGLREYLNVKPGNLSGGQRQRVALARAMVKNPKVFLMDE
                     PLSNLDAKLRNQMRTELIQLHQKLKSTFVYVTHDQVEAMSMADKIVIMNKGKIMQIGS
                     PKKIYQNPKNLFVAQFIGSPCMNILDIKNDIKFGFRPEKATLESINIDGKNDDVFSLF
                     GKVVTKEVLGNETIYCLSVLNREIRVKTENDIFDIGRTLRISVLEKDLYYFDKNGERI
                     EDVKVCKSMYSKIKGDIYEKAI"
     gene            complement(131133..131249)
                     /gene="rrf"
                     /locus_tag="PC466_000117"
     rRNA            complement(131133..131249)
                     /gene="rrf"
                     /locus_tag="PC466_000117"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT        39994 a        25061 c        18039 g        48232 t
ORIGIN      
        1 acacttttaa ttgtttaaat tggaggaaaa aattatggat gaaaatataa caaaaaataa
       61 ttataatgtt ccatttgact atgttcgaaa aaaactcaaa gaattagacc ctcatacaat
      121 tagtaattta agtaatatac ctttcaataa tgatttaaat agattcacac tcaatttttt
      181 tgatagacaa tatattatag actatccaag tggagaagtt tggaatagta atggtagcct
      241 ttgcaataac tttgagctta aaatcttgat agttagatat ttaatcaatg ctaaaggtat
      301 ccctagaact aataaatatg taacttttaa agaaatacca ggaggcaatg tttattatcc
      361 aaatttttta aacaggactc tatataggct ttcagaagtt tttacatctc aaatagacaa
      421 atataagtta gttatggaga aaattggagc tgaaaaagta aacatgggag atttagctta
      481 taggtttaca tatatgggta atacatctat gatatttata ctttggtttg gagatgatga
      541 atttcctcca aattcaaata tattatttga ttctaatata gtttattact tcaatgcaga
      601 agatttagca gttgttcctg atacagctat aaatgcaatt ttaaataaaa taaatcaatt
      661 ataaatataa ataatattat aataaagttt ttgatagatt taatagaata taatatgaaa
      721 tggggtaaaa aatgaatgta gaaaatcaat ctttatcaga tattgaaata atattatcac
      781 acaggtatga taatggtgca gactattgga ctacacctga taagcgttta ataaaaggtt
      841 ctcctttctc tactcttgat agtgtacttt atctattaga gttaggtgtg aaccctgatg
      901 atactttact taaagaatgt gctgacttga tatttagcac atggcgagaa gatggacgtt
      961 tcaaactata tccaaatgga ggtatttacc cttgtcatac tgcaaatgct gctaacgtac
     1021 tctgtcatat gggatatgca tctgacatta gaatgcaaaa aacgtttcaa cattttttag
     1081 atacacagta tactgatggt gggtggcgtt gcaataaatt tagttttggt cgaggtccag
     1141 aaactgaata ctcaaatcca ctaccaactc ttaatatatt aaatgcattc cgttttagta
     1201 attatctaaa taaagaatca aaacttgaca aagctgtaga ttttctactt gaccattgga
     1261 ctattaaaaa accactcggc ccttgtcact atggaattgg cacattattt atgcaagttg
     1321 aatatccttt ccgtaattat aacctattcc tttatgtcta cgttttatca ttttataatc
     1381 gtgcaaaaaa ggataagaga tttttagaag cattgaagat acttgaatct aaaatgatag
     1441 gtaataaaat tgtcgttgaa cgtgtagttc caaaactatc taaattatct ttttgtaaaa
     1501 aaggcgagtc aagtgaaata gccacaacac actattacga aatattaaaa aacctagaaa
     1561 aataatagtt atatagataa aacatattaa aaaatagtgg ctttaaattt tttaaagtca
     1621 ctattctata taaatataac attataaaaa atatattaaa ctatttactc ttttttaaaa
     1681 ccgttgattt tcttgctata taaaaaacta ttattataga aataactact agagaacctc
     1741 tatttataaa gaaataattc tttaattcat taaatctaac atctatatta ttaggcatat
     1801 aaaacatctt ttgaatataa aatccattta cattaatcat actaacaaat gggtacatat
     1861 gtaaaataaa aaatatatca gcaaatgtat atgtaattaa tattgctatt gttgtaaatc
     1921 tattttttgt taatgttaat atcattagtg gaaatgttgt ataccataat aatgtaggaa
     1981 atgtctttaa aaacacatct attggcttta cactataaac aaaatctatt ttgtctatgt
     2041 taaaaccttt cactgacgta aatgtatata ctattgtaat tgaaattaat aataatacag
     2101 tatatatagc taatataaca caccatctaa atactataaa ttgattatat ttttttttat
     2161 tatataaagt aagtatctca tttatattac ccaaataatc ttttgaaaac acataaatta
     2221 ttgtgattgc tgacattatt ggtataaaaa catctgatat ctttataatt cctaaccatc
     2281 ctgctataga atatgtatcc attataggta catcattata aaatattaac tcattataat
     2341 ctaatatgcc tgtaataaat atgcataata tagaaataat tacaaatatt aacacatgtt
     2401 taagctctat ttttttaagc tcaaatttta ttaactccaa tatacacatt tattttaact
     2461 ccttatgtaa aaagtttata taagcatctt gtaaagttgt atctatcctt aagctatcct
     2521 taagtttctc tgtattttta cctatatact ttacttgcac accatcttta actcttctat
     2581 aatcaataat atcaatatta cgttctaaat attcaaattc atcattagaa actactactg
     2641 aatacacctc aaccatatca ataaatttat taattgtacc atcatataat attttgcctt
     2701 gatttaatat aattaatttg tcacagttaa attgtatgtc ttctactatg tgagttgaaa
     2761 ttaatactat agaattttta cttatttctg gtaacaatct tctaaattca ttcctttgct
     2821 ctggatcaag accaactgta ggttcatcca taactattaa cttagaatca cctattaaag
     2881 cctgtgctat acctagtcgt ctctttacac cacctgagta tgtacctatt ttattattta
     2941 taaacttgtc cagattaact tttgatacta ctttttgtat atgtttcttt aaatcattct
     3001 tagatacacc tctcatttta gctacaaact ctaagtattc ttgcccattt atattattat
     3061 acatatcaaa atcttgaggt atatatccta catttgcctt gattttctca ttgtttttgc
     3121 tatactttat attatttaat tctatctctc caattgaagt ttcataaaga gtcactaata
     3181 acctcattaa tgttgatttt ccagcaccat taggacctaa taatgcaact actccatctg
     3241 ttagggttaa atttatatta tccagagctt ttttattttt gtaattaaaa tttagatttc
     3301 ttatttctaa cttgtttatc atattaacct cctttattat ttatctatta taaggatatt
     3361 tcctgaaagc caatgataaa tagttatgct aattttctct ccctttgagt cttcatataa
     3421 aaattcattg ctaggtaagt cagcaactaa tatcatatta attttttttc tttttattga
     3481 ttccataaca ttatctactt catctacata ttttttagca tctacagatg ctttgctatc
     3541 acctaatatt tcatttcttg tttcaattaa aaatttaatt ttttcctcta tatccatatt
     3601 tacattacta tctgatggat agattatttt tatatcatct tttacctctt ctttaaactc
     3661 acctgcatat attgcaatat catttgactt tccttcaaat atataatctt tttttaaaaa
     3721 attactagtc ttattcagta aaggtaaatt tgaatagaca ttatttttag aacttaaatt
     3781 tattttataa gccatacaac ttgattgatt tacttttggg taccacgcta aagaacctgg
     3841 tggaagcata atatcatctt tagtagctat atatttattt tgattccaag atgtcaacac
     3901 attaatatag ccttcatact ctatatctaa tgtcacctcg tcattaggct ctaaactttc
     3961 ctttaaatta acttcaatta aatccttttt tttgttaaat tttatatttt ccgaatttac
     4021 ttttatatat tttatatcaa atatttcatc taaaatcata ttaatatttg ttaactcttc
     4081 atttgatgtg tttaataaaa caattctatc ttttatattt gacttgcttt taaagtcaat
     4141 cttcatatca tgcgatttta ttttaatatc actaatatta gatttcttta aatactctcc
     4201 ataactacgt tcctcatctc tatatgttga catatctatt gatatataat ttaatccaat
     4261 aaataaaata ctgtacacta ctataactat taatgattta atctgtttct ttctaatatc
     4321 atttaatatc agatatgcta ctattattaa agtaattgca aatagtgtag gtataatctt
     4381 atctataaca tatgctgaat tattaacttt ccctacaaaa tcagaatagt aagcatatga
     4441 ttgatcttca aatatattaa gtgatttaaa taatgcttta aaaaatggtt ctttaatatc
     4501 aataactcta tccaacatct tagttgatgt taaatataaa aatactgatg ataaggtaat
     4561 ctttagtatt aaattattta taataactga aataaatgat atcactatag ataaaatagt
     4621 aagtggtaaa aaccattcaa ataccaatat aaatatagtt gatttaatcg ttacaattga
     4681 taatgttctt attaaacttg agtatgctat agcatatata attggtatgc aacaaaatat
     4741 aaagttgttt ctagttacag caacagaaat acctaaaaaa taatcaaaat tatttctaca
     4801 taatattttt acagtatcat aactttttct catataaaaa attacattta acatggttaa
     4861 aatactaatt gtcatacaag tatatacact caaggataag taatcattaa atgaaattcc
     4921 tctattggat atatgtgtcc atcgttgtat gagatggtaa tttataataa taactgttat
     4981 tgcaaataaa atattttttc taattatttt ggttataaag tctgatataa ccttaatact
     5041 actcatattt atgcccctcc tagccaatcc tttgatacaa cttacaatag attcaactat
     5101 atttaataag ttcaaatatt taccttgaca ttatttttta aaattaatat taattagtga
     5161 aattaattaa tttagaaaat gttttataat cttactgatc attattaacc ttcattccaa
     5221 tatatattaa tatagcaatc caatatatag aaattattgc ataaatcaca tattgctgaa
     5281 aaatattaag tattttacat aaaataatta aacatattat tacgaatagt attttttgca
     5341 cagtctttct ataatgcttt ttctcacttt cactaagagg tttgtttcta tgttctaaag
     5401 gagctaactt gtaaattgtt agtatactaa taatcattaa taatactaat aaatacttat
     5461 atttatttat atctatatta ttagctgaaa aaatagttat caaataaata actgcaaatg
     5521 ttaatgtaca ctctttataa ttcctagcat gataacctcc tgtgaactgt cttaaagtgc
     5581 aataacaact taaaaatata actgtatgta taaatctatc aaaaataatt cctataaata
     5641 atgctaccga aatattaact atgaaataaa tcaaagtttc aaatccatat ctatatattt
     5701 caaaatcttc actttctaca atctcattat taactaatat attggcaaat ttatatgata
     5761 atcttttaaa catatttcct cctcaacatg taaaacctct cctttaataa gaagaggtcc
     5821 ttttattaat gttatttttt tagtttttgt aaagcttgtg gctcttttgc ctgatgtgct
     5881 acccaagaac ttgcactgtt tgctgataat acagctatcc caaaacttaa tgctgagatg
     5941 tttttaagta agtttaacgc tatttttttc attttgtact ctcctaactt tttattggta
     6001 tcattatttt taatataaac tcattatctg agtaattaac tattgtttca ccaccatatt
     6061 tatttactat atatttaata ctagcaagtc ctattccatg tatcttatca tcatccttac
     6121 tagtttgaat acgtttatca ataagtttaa tatcatttac cttagtattt ataaatttta
     6181 ttattgcaaa tttatttata tatgtagctt taacttctat tcttttttct agctcattat
     6241 ttatatccat acatgcttca attgcattat ctagtgaatt tgcaaatatt gaacatatat
     6301 cattattttc aataaagttt aatttagata tatttatgtt atcttcaatt tgaatatcat
     6361 actttttaca aatacttatt ttttctgcta aaattaaatc taatgtttta tttccagtat
     6421 ttttaaaatg ttcaaattca cttatctgaa actctaagtt atctatatat gatataattt
     6481 cttctttagt gtcataattt tttatacaaa tcatatggtt tttcaaatca tgataaacat
     6541 attttaatct atcatgaact tcgtttatat tttcataatt cctgtagttt gtttttattc
     6601 tttcatttat aagttcatac tctagattta atttatcgtc ttgtacaatt ttccctatta
     6661 ctattaaaag tattatactt gatgataaaa tcaataaaat tgcaaatata aatataaata
     6721 agttttctgt agtaattgta ttgactctta aattatattc aaatataagt aataagctaa
     6781 ctatattaga taatataggt attcctatta gtatcatatc tttaggttta aaatctaaag
     6841 ataatttaaa atacttaaac aatataaaac ctataaataa aaataccttt gacataataa
     6901 tagcttgtat tctaaataag ttttcatgtt gtgttatgtt aatattattt aatttattta
     6961 taaatactac tagacctact gcagaacctt cagcaatcat taatcctagc caaaacaata
     7021 aactaactat tatactttta tatattttat cttcatatga tgttatataa aatgatattc
     7081 ctattaccat acatagaaga atcttaatat ttggaaacac tttaactaca tttatgtatg
     7141 ccataaatat aaatataatt attgttgtaa atatatatct tatattagat attttcctct
     7201 ttccaactaa gtggattact aaaaaaaata taatccaatc tatagtacct gaaactaaat
     7261 taataatatt ccaaaatcct atacttagat ttgttagcat actatatccc ctaatatatt
     7321 agttatagca agtttcaagc ctttaactct atatttactt attggaatac ttttgccatc
     7381 tactataaca gtacttccac tcattgattc tactaatttt aaattaacta tatagctatt
     7441 atgacatcta aaaaatccat attcatttaa tatcttttct attttagata tactcatttt
     7501 agtaatatac atatcatcat gtgtataaat caatatattc ggtctatctg tttctatata
     7561 agtaatagaa tctattttaa ttcggtctac ataatttttt acatttatag ttaagtaatt
     7621 atttctcttt ttcatcatct catttataca aggtaataca cttttagaaa ttttttcttt
     7681 atttattggc tttagtatat atctgtatgc ttttacctca taaccttctt gcataaactc
     7741 tacaaatgaa gtaacaaata ttatttctaa cttatgatca aactctctta tcttcctagc
     7801 agtatccata ccatttattg ttttcatttg tatgtccata attaatatgt ctaaatcttt
     7861 aggatagtta tttagtaact cttctcctga tgaaaattca tatatgttat aatttatagg
     7921 atatgaactt aatatttcac ttaatatatc ttttattttt attcgataat gtagttcatc
     7981 atcacatatt cctatactaa tcacaattct taaacatcct ttcttatata tttttaataa
     8041 atatataaaa tttctattca ttttacatat tttaacatac ttctgtagca aatagctatt
     8101 tagattttaa ttttagcttt ttggacatta agtattactt tttggattta caatctattt
     8161 taattttcat tataatacaa ttttttaata tatattgaat atatttagcg attttaataa
     8221 catattcttc gagaagtttt tagtatctag tttttgttaa acaaaaagta tgcaccttcc
     8281 tttttatagt aatattttaa ttatcgctat aattttgaag aatacacact atattttaaa
     8341 tattcatata aaacatatta aaaaatagtg gctttaaatt ttttaaagcc actatttttt
     8401 taaatgatgt tcctgaaaat atattaagtt agttattcta atcaatttga agacttttgc
     8461 ttctccttgc ctatatctaa cataatttca taatttaatt tacctttctt taaatcaact
     8521 cctgagttac ttctaataat cccacaatcc aacatttcgt caaatacctt cctagataaa
     8581 cctagtttct cacgtaataa tgttgatacc tttaactgac atggatattt actaataata
     8641 tgaacttgtg taaggtcatt aatattaatt tcttgtccta ctattttata ctctggaata
     8701 ccaacttctg ctccatttct atgtaaaagt tccgtattca tagcatattg cttagcaaga
     8761 ttataatcgt ttgtatggaa ttgttctagt gtttctggat ttaagctttt tggattgaca
     8821 cgagaatata tagttgagtt ccatgttgaa tcacaatttg aacacttgta tattaaccat
     8881 atatccaaat atttatgttg agcattaacc ctaaataaac ctgaacaaat atattcagtc
     8941 ttttttccac atttcttaca atacctaatt acaggtaact gggagatata ttccacctcc
     9001 caagtaattt ttttcataaa tgcaacttcc tttctataag attactaaat taatagaaag
     9061 ttatgaaaag gtggaatata atcaagtatt tttttcaaaa caagacctcc taattttaat
     9121 aaattttaat ttcaaacata taaaaagcta ctacttctta ttagatactt tacaactcta
     9181 ttcgttatct gctgtacaag ttattgaaat tatttaaatt atagcatcca cttataagaa
     9241 actatacctc aaacactttt atcaaaagaa aatgagccag tataattata aaactatact
     9301 ggctcattct taactatctt ttcttttttc ttgtaataca attctttgaa tacttttcaa
     9361 agacaagtaa tatttttctg ataaatattt caaatcatat ccaacttgat aatcttcata
     9421 aatttgcata tttctaattg ataaatcttc acgagtagac gtactacttc cccattcttt
     9481 tttattatta gactttctag gaatatagat atattctcca tctacatatt cctgtatcaa
     9541 ttcaagtaat tcttctggta atatatgtat tgctttttta tagctcattc tgcactccta
     9601 ttaaataata attttttatt aggaatagca aagggctatt tatatattaa attttatatt
     9661 tgcaatagcc cttgctatgc aaaaataaag attaaatcaa acataaatct cacccctcct
     9721 tatatattgc aacgatacat ataagtctat cagcagtata aatagttgtc aattaacata
     9781 acttcttcat ctaaccttta tattatcttt atttattttc ataattcatc tattttagag
     9841 actaactttt ttcttcttat tagatatatt taaagttatt aatcaacata agtcctttat
     9901 cttgagggat ttattaccga acaaggaacc ccaactatac actttccaca aatatcacaa
     9961 ccacctatat aagtgtattt tttttcattt atcatacaca tttcataaca cttattccta
    10021 ttaaatccat cttcttttaa agcttctttc acgcatttgt tgacacattt tttgcaacta
    10081 ttattatgtt tatacaagca gtattcattt tctggtcttt tagttggctc taattctaaa
    10141 cttgtgatta tgcttcctat tcttccacaa cacccttttt ctgtaataag catattattt
    10201 aaaccaaatg ttccaagacc tgctatgaat gctacatgtc tttgtgacca gtcacttacc
    10261 aatttttcac tgtcaaaatt atacgaccca ggaatagcat atgaattagc ccccatcttc
    10321 tctagttctt cacataagaa atcatttaaa tttgaaatca acatattagt ttctatgtac
    10381 gctcttgccc atatttcaga acattcaaac cctccaatat tactattatt tacactttca
    10441 tcaaaaggta taaaatatgt aattatagtt tttccatttt ccagaaaatc ttttggcata
    10501 gcatgagatg ttcctacaac actttttagc ttctgaaaca tatcatcttc agcagatgca
    10561 taagcaaaca aaagttcttg ccactttgta gttatattat ttgatttatg ataatttttt
    10621 acaaagttgt tcattgatgt ttcaatctta tttttcatag tatcacccct agataattct
    10681 atatttccaa tttaatgtta ttattttata ttatataata gtattttata atatgcgcac
    10741 taattaatat taaaactatg ttcatcaatc attcttaaaa aagctcctaa tatcaatacg
    10801 atattagaag ccttttctta tctaatctaa tttattgcaa ttcctgcact tgcatatcct
    10861 gctacagtat taactaatga aagacctgaa gctgttgcag taaatactag taagaatcga
    10921 gtttctgctg ttgctgctat atttaatcct gttacaattc cactagaaat tgaaccaact
    10981 gataatatac ctgtaagtgg tggagctagt gtaactgtcg ctcctggtac agctgtaaat
    11041 gagttatttg gtgcagtaga ttggtaaagt gttgctgtaa ttgtaattgt tgaaccaaca
    11101 agtgaaagtg ctgctgttgt actgaagtat gctgaaatag atgttattgt tccatctctt
    11161 ggcattgaaa atgcaaagtt agtcaatgtc cctgctgcgt ttgtaaggtc tattactcca
    11221 ccaactatac ttaatcctgg agctgaacta ccaaagccaa caaaacctgg tgtacctact
    11281 aatcctccag ctatagttgt aagtgatagt ggtatacctg atgcaaaagg tattattgca
    11341 ctagcacctg ttgggcctgt tggacctgtt gcccctgttg ctcccgttgc tccggttgga
    11401 cctactaatc catctgcccc tgttggacct gttgctccgg ttgcccctgt tgctccatct
    11461 gctcctgttg gacctgttgc tcctattggg cctgttgctc cggttgctcc tgctaatcct
    11521 gttgctccgg ttgctcctgt tggacctact aatccgtctg ctcctgttgg acctgttgcc
    11581 cctgttggac ctgttgctcc atctgctcct gtatttcctg ttgcccctgt tgctccggtt
    11641 ggacctgcta ctccatctgc tcctgttgct cccgtcgctc cggttggacc tactaatcca
    11701 tctgctcctg ttggacctgt cgctcctgtt gctccggttg ctccagttat tcctactccg
    11761 gttgcccctg ttggacctgt tgggcctact aatccatctg ctcctgttgc ccctgttgct
    11821 cctgttggac ctactaatcc atctgctcct gttggacctg ttgctccggt tgcccctgtc
    11881 gctcctgttg ctccatctgc tccggttact cctgttgccc cggttggtcc tattagtcct
    11941 gctgctcctg ttgcccctgt tactcctgtt gggcctgttg ctccggttgc tccggttgct
    12001 ccggttggac ctattaaccc tgttgctcct gttattccta ttcctgttgc tcctgttgcc
    12061 cctgttgggc ctgttattcc tattcctgtt gctcctgttg ctcctgttgg gcctgttact
    12121 ccatctgctc ctgttgcccc tgttgggcct gttgggcctg ttactcctgt tgctccatct
    12181 gcccctgttg ctcctgttgc tcctgttgga cctgttattc ctattcctgt tgctcctatt
    12241 gcccctgttg gacctgttgc tccaggtgtt cctgtcgctc ctgttggacc tattaatcct
    12301 gttgctcctg ttactcctac tcctgttgct cctgttgggc ctgttggacc tgttactcca
    12361 aatcctgttg cccctgttgc tcctgttgga cctgttattc catctgctcc tgttgctccc
    12421 gttggacctg ttggacctgt tactccatct gctcctgttg ctcctgtcgc tcctgttggg
    12481 cctgttgggc ctgttactcc aaaccctata gctcctgtcg ctcctgttgg gcctgttccc
    12541 cctgttgctc ctgttggacc tcttaatcct gttgctcctg tattccctgt atttcctgtt
    12601 gggccagtcg gaccggttgg tcctgttggg cctgttcccc ctactcctgg acctgttgga
    12661 cccgttggtc ctgttgggcc ggttctacct cttggaccca ttgggcctgt tggacctaca
    12721 catgatggtg gacagcaatg atggcaatca cagctattat aatcatcacg accattatta
    12781 caatcatcat atttatcata gccattgttg taatcattat catcaaatgg tccaaaatat
    12841 ttatttctac tcattattaa aagcacctcc tgatatattt gagcttttaa gctctatata
    12901 taatatgtca aatttagtat gattgtgacc tatcaactat ttttaaattt actaaaataa
    12961 ttttcattgt gcaaaacagc actatcgtta ggtttgattt cttttgtttt ttcatgataa
    13021 taaatagctt tatctgattc tcctaacctg tcataacaga cacttaattg tatagatggt
    13081 atatatccat aacaatcatt tgacttaaaa cctccattag tatcattctt atctcttgtt
    13141 aatgctacct tataccaaaa aatggcttct ttatattttt gtctatcaaa catatgcttt
    13201 cctatgtcac aacaaatttc tgctcttggc tcatcaaatt cgaaacttct aaacaatgaa
    13261 tataaggcac ttttttcatc attaattaag taataacatg tggctaaatc tctgcaggca
    13321 ctgatacaat cctcaatcca tcctcttgat gagtctaaaa acttagtaaa accttctatt
    13381 gcttctttat acctagcatt atagtacaac tctctagagt aatagaattg gtgtcttggc
    13441 tccaatgttt ttccttctga aatcattttt tcaaaaattc taagatttct tagagggtcc
    13501 tgtctatgaa gctttttatg agatattgca atgtcagaat aaaatacctc tccaaaaaga
    13561 ggtactactt catgaatagg gtcaacccat ttatgattag aacttctttt aaacaatcgt
    13621 tctctataat atgagagagt tgggttacca ttttcatcaa aggatacatt gtattttgcc
    13681 ataacaatat caatggaagt atccaagctt tctttaatct ttaataattt ttctctatca
    13741 gcttctaaaa ttatgtcatc tgcatcaagc cacatagtat agtctttaga agctttagaa
    13801 aatgaaaaat ttcttgcagc agagaaatca tctatccatt cgaaatcgta caccatgtct
    13861 gtatattttg agactatttc ttttgtggaa tctgtagaac cggtatctac aattataatt
    13921 tcgtctacta tatcctttac acattctaag catctgccta taacttcttc ctcattctta
    13981 acaatcatgc acaaacttat tgcaatcata atgtacaact cctttgtctt ctatatattg
    14041 cagacataag taatatatgg tattttctct tgttttgtta ttaaatttat aaaaactttt
    14101 gacgacagaa agttactaaa gaaccttatc ttttatgtat tttttatagt agaatttatt
    14161 aaacttgaaa tttggtaata attgttgaaa tgataaaacc atatttaatt tcatacaaaa
    14221 aagagtgtcc cataaactaa aaagttcatt ttgagacact cttatttaat attatatata
    14281 tatttgtaaa acagacattt taatatgata ctttgatact ttattcattc ctattcattc
    14341 ctattcatta tataatcaat cagcccgtac tctttagcct ctagtgcagt cataaaatta
    14401 tctctatctg tatctcttct aatatcttct attgatttac ctgtattttc agaaagaatt
    14461 ttatctaatc gttcttttat tttcaatata ttatctacag ctatttttac atctgttgct
    14521 tgacctttag ctcctcccat tggctgatga atcataatct ctgaattggg taaagcacat
    14581 ctttttccat gtgttcctcc tgcaagtaaa aaagcactca tacttgcagc cataccaata
    14641 cagatagtcg atacatcaca tctgacataa ttcatagtat catatatagc aaatcctgat
    14701 gtagcagagc caccagggct atttatatat ataattatat ctgaatctgg gtcttctgat
    14761 tctaaaaaca gtaattgagc tactactaaa cttgcaatag catcattaat ttcttctcct
    14821 ataaatataa ttctatcttt taataatttt gaatatatat cataagacct ttccccttga
    14881 cctgtttgtt caattacatg tggcactaaa ctcatgctac tttcacctca caattaatat
    14941 taaagttaag ataagaattg atttcatctc ttctttgttt ataattcata tttgcataag
    15001 aaatacattt ttcgctttga atttgatgat ttagatttaa aacaaatctc tgttgaatag
    15061 gataaaattc atctttattt ctatatactt gtggagattc tttatataaa tttctaaatg
    15121 ctagtgtaaa agattgatgt gtagaatatc ctactgtaat agctatatct ataatatatt
    15181 tgtctgtaaa tataagttgt ctagctgctt cagtaagtct cctcctctgt atgtattgat
    15241 ggatagtaca tcctacaaca tttgtaaaca ttctgtgtaa atggtatttt gaataattag
    15301 caatataagc tattttatct aaatttagat tttctgtaag attttcttct atataatcaa
    15361 ttatctccat aataacatct gtatttgttt tcaactctat cctctccttt taagtattat
    15421 aacctatgca aaaagttttt tcttaatata aattgctatc ttaatttagt gtatagcaat
    15481 aaagtatcga taaaacaata tcaagtattt ttatacaaaa atattaatat atatttcttt
    15541 taaagtttaa acttaattac atctattata tgtagattgc tacatgtttt atctatgtac
    15601 cttgattcat atgtattatt ttgctgagta tttttacacc tttttcaatt tcatcaaaac
    15661 taagatgagc ataacctagt ataatttcat ggtcatattc taatatattc tcaattgcat
    15721 attgttgtat aggataaact tttatacctg cttcaaaaat tttatgaatt aaactttccg
    15781 taaatttaac attatagaaa tgagcaacta tatgaagccc tgctgcttca ccttttattt
    15841 taaattcatt tttaaattcc gtgtttaaaa cttttatgag atatttacgt tttctattgt
    15901 acaacttctt cattctaaat atgtacttct ctaaacctcc atttccaata aattcagcta
    15961 atacatattg caatattgtt tctgtatgaa catcagagta catttttaag gttttatagc
    16021 tttctaaaat attgtctggt aataacataa atccaacacg aatagctgga gataatattt
    16081 tactaaaaga acctatgtaa attactttat ttgggctaag ttcataaaga gaactaattg
    16141 gttgaccctc atatctaaat tcactatcat aatcatcttc aattatatag taatcattct
    16201 ctgttgcaca tttaataagc tctagtcttc tttgaatagg taaaatccct cctaatggat
    16261 attgatgaga aggtgtagta taaacaaaag aaatcccctt tattgatttt attaagttgg
    16321 tattcattcc cttatcatct actttaattc caacaactga atatccaata gatgaaataa
    16381 cctttaataa gcctttatga atagggtctt ctacagcaac ctttttatta cttttgtata
    16441 aaagctgtga aattaaagat aaaccttgtg ttgaaccaga aacaatcata atgtttttgg
    16501 aattacatct aattcctcta gtacgaaata aatacttaga tatttccact cttaaaaccc
    16561 atacaccagc tgtacttcca tatctgaaat ccgaatctga taaatcatac agtatttgtt
    16621 tatatagctt tgaaagttct ttgcgtggaa atagttttaa ttctggaact cctgaacgaa
    16681 aatctatata atttttttgt ttattagtat gtaaatcttt ttcatctcta aaagtatcat
    16741 ttaacttaaa atcaacttta tgccctgata ttcctttagc tacaattgtt ccatatccat
    16801 tccttgtttc caaatatcct tctgcaatta attgattata tgcatctaaa actgtattac
    16861 gagatacaga tagttctttt gataaagtcc tagatgatgg cagtttttgc tcaaacttta
    16921 agcttccatc cagaatcata tcttttatct cacaataaat ttgtcttgat aatgatatat
    16981 tactatttct attaatcgta atccacattc taatacctcc aaaagtggtt ctataaaatt
    17041 actataaaaa tggaactaca aaatccactt ttaacttgct aagattatat cataaaatat
    17101 aaaataaaaa ggagtctata ttatgttaga aatatcacat aaagttaaag aaatttatcc
    17161 caatattaaa tttggagtta tggttataaa tattacacat tcaaaaccta ataaagaaaa
    17221 ttttttagtt cttaaaaact ctacaattaa aaatattata gaacaacacc cagaatacaa
    17281 tcgtaaagaa aaaattaaaa cagagcctgt ttcaagttat ataaagtatt ataaaaaatt
    17341 caagaaaact taccctgtat tgcttcaatt agaatctatt ctattaaaat caaaaggtat
    17401 cccagatgta ggtgtaacaa ttgagtcaat gtttttagca gaattgaaaa atcttcttct
    17461 aacagcaggt catgaccttg ataaaatgga attacctttg aaaatagaat tagcaaatgg
    17521 aagtgaacat ttttatggta taggtggtaa agagcatatt ttaacaaaag atgatttatt
    17581 tttatcagat aatattggta tattatctag tattcttaat ggccctgata atcgaacagc
    17641 tataacaaaa gatactaaaa atattatgta ttttgtatat ggacctgata aaatatcaga
    17701 aaagcaaatt caagaccatt taaatgacat aaaacactat atttcaagtg cttttccaga
    17761 tttaaaagtt aattcaattg atatatttta gttaatatat taaaatcctc ataaatattt
    17821 tgaataaata aattagtgaa gtatacattc tagttaaact agatatactt cactaaaatt
    17881 aattatatgt agatattatt tattttgaat tttgtttata ataaacactt tattacattt
    17941 atcctatgaa taacttaatt ttataattaa agagtttcat aagaaacaat ttcacttaaa
    18001 ggaacacgag ttttttcatg tctctctggg ctctctggta tcttagattc atatcccatc
    18061 aataatatat ttattggttc tagattatct ggcaaactaa actcttctct aattatatct
    18121 ggattaaaat agcacaccca aacacttgcc aatccaagtt cagttgcctg taacatcata
    18181 tggtctgtaa ctatacttgt gtcaatatct gtaagttgtc tcccatcaaa aggtcttgtc
    18241 caaactttgt ctttatctcc acatacaaga attgctaatg gagcatcata tatattggca
    18301 gccttagaaa gtttatttat accttctttt tcctgaataa caatcaatct ttgaggttga
    18361 cgattaccac cagttggagc tattcttgca acatctaaaa ccttctcaag tttttctttt
    18421 tcaacctttc tatcttgata attacggcaa gaatatcttt tttttgtaag ttcaacgaaa
    18481 ttcatttatt taccccctat tgttttatta ggctaagttg atgatttatt taacctatgc
    18541 tataatttta tcactatggt actatattac aataatgcac ttttttgtaa tatagtatct
    18601 aaaaagatac tttaaaataa ataaaggagc tcaaaaatga aaaaatgttt agataattac
    18661 agttgcccaa tagaagcaac acttgcattg attggtggta aatataagac acttatactt
    18721 tggcatctta aagacactat attgaggttt aatgaattaa aaaaattaat tcctaaagca
    18781 acgcctaaga tgttaactca acaattacgt gaattagaat cagatggttt aattataaga
    18841 gtggtttatc ctgttgttcc tccaaaagta gaatactcgc tatctgattt tggaaagagt
    18901 attattccaa ttttagattc catgtgtgac tggggttctg attacttaga aagtctatag
    18961 agcattacag tttaaatccc attgctaatt taacttcatc catttgttct ctagatgtca
    19021 acatttctaa aagcttaaaa gctacatgtg gagctgtttc tggacaatat gaggttataa
    19081 tatttttatc tacaacaatt ggttcattaa ctacatttac atcaaactca cttaactgtc
    19141 tttgtctttt accatttttc aaatgatatg tagtagcttt acgatttttt aaaacaccac
    19201 tttttccaac tggcaatgct gccacacaaa tagaagcgat tattttttct tttgaattaa
    19261 actcccttat tagatttaaa aaagatgaat catatgcttc atcataaaat ccaaattctt
    19321 caaatcctcc aggaatagct agggcatcat aatcatcaac acatacttct tctatcgtct
    19381 tatcaactaa tacttgtata ttaaatgtac tcataacttg ttttttaaat ccacaagtca
    19441 ctacatcaat atcatgccca taatcgttac gagcccatcc cataacatct acaaatacac
    19501 taaattccat agtttcaaaa ccttttgcta aaaaaactaa aactttcata ttctattttc
    19561 ctcctaaaat ataattaaca ctttactagt aaattattta aaaaatatct tttattgtat
    19621 taaattcttc tttaattgta gataaaacaa tggttgtatt agctttttga atccccccaa
    19681 tttccttcaa agtcactgat ataaactctt caagattact tgtatcttct gctaatactt
    19741 ttattaagta atcatactct cctgaaatat gatgacattc taatacagta tcatattcca
    19801 atatagtttt cttaaattct ttcatacttt tagataaatc agtattgata aatataaaag
    19861 ccaaaagctt atattttgtt ttttcccgat taatttgaat agtgtacttt tgaattaaat
    19921 ttgactgctc aattttcctt atacgctctg agactgctgg tactgataaa ttaatttgtc
    19981 tgcttatttc agaggttgaa gccctactat tcttttttag agaattaatt atttttaaat
    20041 ctatttcatc cagagctact cacctcctta attatttaat acaattttag ctaataattt
    20101 acattaagta aataaattta atcatttcaa taaaatttaa tacaaatatg ttatttttcc
    20161 ttaaaatttt agttttcttt aatcaaaaca catataatac ttaaaattat ttaagttgaa
    20221 ttaatgtttt tattttgtat aatatattag aaccttaata tatcattgaa aattcaacaa
    20281 tactagacat atacttctac atgttgtaat atttatgaaa atagtatccc tatatcaaaa
    20341 gtataaaact cataatctta attttcccat agactataaa attttattgg tagcgagtct
    20401 tcaaataact ttgtaatgat agatttacta aattaatata atatatagca aatataactt
    20461 tcttattgac tataaccaag tattatgata acataactta agctataatt aataaaacat
    20521 attttaaata aataagataa tccacaaagt acaaaagtac aatttaaata tagataaact
    20581 agaattaata ctaaaattag gatgtgaata attatgattt atatagaatt agttaaactt
    20641 gttagaaaac ttaactctac acaaatgtat acgatgaagc gttgtgtaga ggttaatctg
    20701 aaagcttaaa gctttctatc ttcatcggca aatataggtt tagtatagtt ttttggctat
    20761 gcttatttaa aattacctat ttgccgatag atagtataga ttttctggtc atagacaaca
    20821 atgcttgtct atgacctttt gtttttccaa aagcagaggt cggcatttta caatgccatt
    20881 cctctgcttt ttttatttcc ataaattttt taataaaaga aaaggagttt gaattatgag
    20941 tttattaaaa gtaactaatt tatcacaatg ttttatggat aaatcactgt atgagaaagc
    21001 taactttgat ttattcaaag gtgaacatat aggtgtagtt ggccaaaatg gtacaggtaa
    21061 aagtacatta attaaaattt tattgggaga agttgttcca gattcaggag aaatcaagtg
    21121 gcaacctaat atcaatatag gccatttaga ccaatatgca gaaatcaata gagatacaac
    21181 aatatcactc tatttacaca ctgcatttga agaactttat aaaatagaaa aggaaatgaa
    21241 tttactctat caaaaaagtg ctatatctga aaatgagcaa tatctaatca aagcatcaga
    21301 ttatcaggaa caactaatag caagtaattt ctattctata gataatgaaa taaataaaat
    21361 agcaaatggt cttggattag attcaatagg aatgaatcgt gttgttgaag agcttagtgg
    21421 tgggcaaagg gcaaaggtaa ttttagcaaa attgctactt tctaaccatg atgttctatt
    21481 attagatgaa ccaacaaact ttttagataa agaacatgtt gaatggctct caaattattt
    21541 aaatacattt aatggggcat ttattgtagt ttcccacgat tttgattttt tagaaaaaat
    21601 ttctacaggt attcttgata tagaatttgg tatgattaaa aaatatcatg gaaaatattc
    21661 agagttcctt aaacaaaaat cacatttaag agaagattat attagaaggt atcaagcaca
    21721 acaaaagaaa atagaaaaag aagagacatt tatacgtaaa aataaagctg gagtaaattc
    21781 aaaaattgca agaggaagac aaaaacaatt ggataaaata gaaagaatag ctcctcctag
    21841 ttttacagga aaaccaaata ttcaattttc agaaattgaa atatcggctc aaaatgctct
    21901 tactataaca aatcttgaag ttggatacta ctattcttta cttccaaaat taaatttttc
    21961 tgttgatgga ggtcaaaaaa tagttataac tggttttaat ggaatcggta aatctacctt
    22021 gttaaagaca ttagtcaaag atattcctcg tatatctgga gatttccagt tttcagaaca
    22081 agttaaaatt ggttattatg agcaagattt aaaatgggaa aatcctgata aaaccccact
    22141 tcaaatagta gcagataaat atccaaaatt aaatacaaaa gagattagac gtcatctagc
    22201 cagatgtggt gtgaaggaag agcatgtttc aaggagtgta tctactttaa gtggtggtga
    22261 acaatctaag gttaaattat gttgtatgat gttatctcct tgtaattttc ttattctgga
    22321 tgaaccaacc aatcactttg atgcagagac aaaggatgct ttacaaaatg ctttgaaaca
    22381 gtttagagga agtataatcc tagtttccca tgaagaaaaa ttttataaag gttggattga
    22441 taaagtgttt aatatagaaa aacaattagt ataagtttat acacaatata caatattatt
    22501 taattgatat ttcaatgcaa attttaatgt tctagttaat gtttcactgc aaataaacta
    22561 aaaaaatttt attagaacat aaagtacatt accaggatat aaacttaatg aggctatctc
    22621 aaaatagaga tagacctctt cttcattgtt gagataacga aaatacattt gacttcacac
    22681 ataaaagaat gcctcattaa ctaaaaattc aacttgagac atcttcatta atattaaaat
    22741 ctattctaat cgattctatt cacaagttta tatcctagtc ctttaaccgt tataagtatt
    22801 ttaggatttg aggggttatc ttcaattttt tctcttatat gtcgtatatg caccataatt
    22861 gtattgtcac aaatactact atatactccc catacttgtt catagagtct ttcttttcct
    22921 ataattttat ttacattttg agccatgtag cttaaaagat gatactccct tccagttaac
    22981 tcaatctcat ttctatcttt atatacacgg tttccttcta tatcaatagt aatatctcct
    23041 attttaataa ctgcactatc tgatggtaca atgctttgat actgttgtct acgtaattgc
    23101 gctttaactc gaaaagcaat ttctcttgga ctgaatggct ttgttatata gtcatctccc
    23161 ccactactaa gacctagtat tttgtcaata tcatcatttt ttgatgataa aaaaagaata
    23221 gaacagtatg aaaactctcg aattttttta cacacttcta taccatctat atctggtaac
    23281 attatatcaa gaatgacaac atctggacat gctatcttac acagcgaaat agcatctaaa
    23341 ccattataag ctttaataat gtttttaaaa ccatcattta tgagtacttc ttcaattaaa
    23401 tctactatat ctttttcatc atcaacaagt aatatttttt tattaaaata tgtatccata
    23461 ttgaaatctc tccataaaaa tttattatat tctaatcttg cagtatcaat atcttgtttt
    23521 tttatattca ctactcttgc ttttacatta ctaatagtaa catctctaat agacaaattc
    23581 aatcactatg aaaattaaga taagtttctt taaaataaag tgtatgatac attaaaacct
    23641 atagaaaatt aatttcatcc aaagtttata atattagact aatacactta cagatacaga
    23701 tacagattaa tacaatagta aaataaaagg agttgtctta aaattgactt tttctaatca
    23761 aactttaagt tcaactccct tttaaacttt tatatgttat ttttattaat tctttatatc
    23821 aattataact ttaattttca atagtatata tctaccacta attgaattac ttattaaaac
    23881 ataaaatatc tacctaaact atttatttaa tatctacata tatttatatc tattcttata
    23941 cttacatata caaaaaatgg ttaaaaataa agttaaaatc tcagcacttg gtactgctaa
    24001 ccatatccca tttatattta atatatttgg cagtatcaat aaacctatag ttataaatcc
    24061 aaatgtacgt agaaaagata atattgcaga gaccttgcca tttgacaatg ctgtaaacat
    24121 agacgaagta aaaatattat acccacaaaa aataaaacta aaagaaaata tataaaatcc
    24181 agaccttgca atttcataaa ctcggcttcc tctttgagaa aaaatctcta caatgattgg
    24241 tgaacatgat atagaaaaga taaataccaa taaagatgcc actgaaataa ataatataca
    24301 aatcttaaaa acatgattta actgtgtatt attttcactt ccatagttat aacttattat
    24361 tggtgcaaca cccattgaga aacctatata aagcgaagtt aaaagaaatt gagaataaat
    24421 aattattgta atagctgcaa ctccatcctc accaattaat ttcatcatca tagcattaaa
    24481 taaaaaagta gtaactgctg ttgatagttg acctaccatt tcagatgaac cattaaaaca
    24541 agcttcaaat aatattcttt tatctagtct gggtatacaa aacttaagta actctttatt
    24601 ttttgaaaag aaaaccatac ctgaaacggt aggaattagg tatcctactc cagttgcaag
    24661 tgctgctcca ctaataccca tttgtaacag aacaatgaac acatagtcaa gaattatatt
    24721 agcacaccca gcacctaaca ctagccataa tccaaattga ggctttccag ctgttacaaa
    24781 taaacattga aataatactt gtagtatatt tgcagaagca aaaaccaaga taataaaaag
    24841 atatgaacga caatatttaa ttaaaacttc acttgctcct aaccatataa tgatataatc
    24901 cataaataca atacctatac cagtaattat taccccaatt acaactcctg ataatacgat
    24961 taaagaaaaa gctttatttg ctccctcaat atcaccattt cccatcttac gtgctacaat
    25021 agcacttcct ccagtggcaa gcatagttcc aattccaact ataagattaa taattggaca
    25081 tacaatatta attgctgata gagcatttgt attaataaat cttgatacaa atatagtatc
    25141 tacgattgta tacaacccca taaaaatcat cataaaaata gtaggaaatg caaacttcaa
    25201 tagagtaaat aaattaaatc tttgtgccag taaattatct tgctcataaa gattatcttg
    25261 ttcatgattt tctgaataat atacatcact cattttgttt atttttctgt acattaatta
    25321 tttttaaaat atattccaaa caattagaca tttacagacc tcctttctgc ataagaatta
    25381 tatctaatta tttggatata gttttaatta atcttgcttt tttacacaat tatatttcta
    25441 ctaaagaaac ttttaaatcc ttactttaat cattttatag ctttcagtgc ctttagcgca
    25501 aatacttgtt cacatagttt agtgtcatat gaaacgtatt tatatatagt tatacattgt
    25561 ctatttttac taatttatta actacttgca cttttataat gtctcatacc taacttccaa
    25621 aatctccaca taaacaatgt aaacaaaaat acaattaaaa ttgagtatat taatccatta
    25681 attgttattg tcccagccaa aatttgagtc ggaattgtcg acataattcc atatggtaag
    25741 attaaataga ataatacttt aaaaacacct tcatatatta caccaggaat tttcatattc
    25801 attggcaata aattatcttc taatctcatt atcgcagaag atgatataac aaaaaatgaa
    25861 actgttctaa gtatgataca tacatcataa aaaagtaatg tcatcaataa caccatgaaa
    25921 atatatatta ttatcataac taaagttatc tctgagttta acttagatat tccatataaa
    25981 acaataagta tacttgctag aattaatggt gatgaaccaa tattaatatt ttcaaatgtt
    26041 aacctaaata gtgggtctaa tggttttgta atatagtagt ctaattctcc ttcttggatt
    26101 tttcgtggaa tatcataaat accaaaaaag aaaatcgtca tatttatcgc atttattaat
    26161 gagaaagttc ctataaatat taacatctct ccttgttgcc atccccctat tgagtctaca
    26221 tgagaatata tactattaaa cattagaagt tgtaatataa ataatgaact atctacaaaa
    26281 aatgctccaa aaaaatcaaa tctaaatacc atcatctttg ataatttcat ttttaataac
    26341 ataaatatta ttttcaaatt ttttttcatc atatacccac cccatcaaat aatgttctca
    26401 ttcttttata cataacttta tttactacag aaaaaaataa aacccataat gctagaataa
    26461 ttaatccttg tattgcctca ttgctgtttc tacctattag taacatagat ggcaaatatg
    26521 ttgtataata aaatggaaat accttcataa ctgttactat agtttctggt aagagtacaa
    26581 gtggtatcat tgttcctgta ataaattcaa caatattttc aattatcatt ctaaaaaaac
    26641 taatctcaag aaatttaaat gacaaaatcc caataaagaa gtggagtttc atcataaaaa
    26701 taaaccctag aaaaatcatc aaaattgaaa ttaatatttg aactggattt gatgtaaagg
    26761 caaaatctat tttaaatata aaaatccata caaatgcaga aatcatatta aatacaaaat
    26821 aaaaacatgt cattccaaaa tttttagcaa taaaataatt ttgaacatta attggaataa
    26881 tcatgtactt tgaaaatgtg cccaatttta cacgattaca tatctcttca ctggtactct
    26941 ttgacatatc aatacctgct aaaaatgagc ttattatata gtaagacaac atagagttaa
    27001 atgtaaaacc agagactatt ttattttcac caaaaattgc tttccataaa atataagcaa
    27061 ataaaatttt tacaatcgta aacaccatat taaccaccac atcaaatctc cagataagtt
    27121 gcactttaaa gttaattttg gctacttcat aataccttct aatactttgt ttaaatttat
    27181 aaaacattga ataatttgaa cttgcttcat tatagttgct cataatactc atcacttcct
    27241 ttcttatata ttctctctac aatactacct atatcttctt cttcaatcat tacatcttta
    27301 acatcatatt tatcaaaaat ccatttaatc gtttcatttc ctctttcttt tagcacaatt
    27361 actgatgtct tatgatttgt ttgttcaaca actttacaat cttttggaaa tacaatgtta
    27421 gtttcattgg aaaaactaac tgttattttt ttatattttt gaaaatgatt aaatagtttc
    27481 tctgtagaac catcatatat tttacggcta ttttctacaa caatacttct actacagaga
    27541 ctcttaatat cttccatgta atgagaagta agtataatag tagttccttt tgtttcattt
    27601 acttctttta ggaaatacct aatttgtttt tgggctatag catctaagcc tatagttggt
    27661 tcatccaaaa ataatatttt tggattatgt agaagggcta ctattaattc cattttcatt
    27721 ctttctccta aagaaagcgt cctaacttga acatttaaat agtcagatac ctcaaataat
    27781 tcgataaagt aatccaagtt ttttttatat tcttcattag atatatcata taattcttta
    27841 aataaaagaa acgtatctgc tggtgtcaat tcaaagaata gttgactttt ttggcccata
    27901 acaacagcat attgtttttt aaaattattt tctaatttgt tagggtaata acccataaca
    27961 gatatttctc cagaagacgg tgcaataata ccagttaaca tcttaataag agtagttttg
    28021 ccagctccat tttgacctat taatccaaca aattctcctt cttctatctt taaatcaaat
    28081 gacgatatag ctgttttttc tgtatatttc ctattaaata aagactttac actccccata
    28141 aatcctgcct ttttctcaaa tcttctataa gatttagtca gttcattaag ttcaattata
    28201 ctcattttaa ctacctccat atttcataat ttatataaaa aaagtccaca ggtatatatc
    28261 tgcctttttc tgtgcttata tttaacagca caaaaacaga aaactcctgt ggactagaaa
    28321 aattaatgct ctctatttca aaatagttat caaaataata ctatacaaaa ttaataaaag
    28381 tgtagcagat taaagcctac tacaccataa tttaacaaag taatatatat tttaaatact
    28441 atttgttgtc atatgtcagt tatctataaa ggcagaataa gacacaaaaa ttaaatgtat
    28501 taaaaataca cttaaaattt ctgattatac agaatatatg tgtctccaac tatttaattg
    28561 ttggttacca ttatataact ccgacatcaa ggcactcctc tcataatatt attattgata
    28621 tcatatcata aaggttattt atgttcaagt atggatttat atactaatac atttagctta
    28681 tttcttcagg gttgaattta aatttcattt ataatattcg tttataaatt aaaaatataa
    28741 tacgtatatt aaaactggtt attttactgt aatattttta ttgtaaaaga tatactttta
    28801 cctatacagg atgtaatttc tttagttcta tattataata atattgtaat aagagttcaa
    28861 cttataatac agtaaaatat aaactgtaaa tcttaagggg gtaatctatg gaaaataata
    28921 caatacaaaa acaattaaga gatttatcaa aaaaaatttg gcatatttat attttaaatc
    28981 cagaagaaga aaaccttaaa tttattattt ccttattaga taacaacctt gcattaattg
    29041 gaacaggaaa acatgaattt tacgaaacat tagaagaatt tattataggt cttgaaaaag
    29101 accaaacaga atcagagcaa atagactttg agattataga tgagtggtat tcatgtacca
    29161 aagttacaga cgaagctttt atagtatatg gtactctttg ggtaatagaa aaagattacc
    29221 tagaaaaaga tatctatgta gaaatggata ctcgatttac tatggtatac agagttacag
    29281 atgatatgat taaacttatc catgttcacc attctattcc aaactttgac caaatgaaag
    29341 atgagtatta ccctaaaaca ataactgaaa aagcacaaga agcactagca atggcaaatg
    29401 aatttaaact aaaatcagaa aaagacctta tgactggact atacaataga catttttttg
    29461 aagtacacat aaaagaaatg cttaaaactg tttcatatgg atacttttac atctttgatt
    29521 tagataattt taaacaggta aatgatatct ttggtcatgt tcgaggagat gaaatactaa
    29581 tacagttttc aaatattttg actaaagtat tcgtaaatga tgctattatt ggaagacttg
    29641 gtggagatga atttgctgtt tttgaatata gtaatcaatc aaaagagaat gttgaaaata
    29701 aagcaaagaa agttttagaa ttatgtctag agagtaattc ttgttctata ggtatatcta
    29761 aattagaaaa taaatctgat actttccagt ctttatacaa acaatcggat tatgctttgt
    29821 attattcaaa acgaaataat aaaggaaact ttagttggtt ttagtacaaa agatattaaa
    29881 ataggcaaat ttattagagt atcttgtcct atatactaat aagtaaagta aacaacaagc
    29941 tatctttgca tatatttata taaaccaact attcttaata aaactacaat agtcaacatg
    30001 accactatta tagaatataa taaactaaaa acattattaa catgattaat attatatttt
    30061 aataatttta tttttaaaag taagtccaaa atgttatatt ttttgattaa aactgatgtt
    30121 gatataaaaa attttactta aaaaaacact tagaaaggct ttataaagag ccttttttgc
    30181 ttttattgat taaattttca tataaaattc cttattaaat ttcaaatcaa taaaaaaagg
    30241 ctctttataa agcctcccct atttttattg attaaatcct aatatagaca atgccttagc
    30301 atcatagtaa gtagtcatct ctcttgttgc atcctttaat ttacggtaat caaagtctaa
    30361 tgctccacca aaagctgata tttcagaccc atcagaccta taccatttcc catcaatttg
    30421 tatatagttc caagcatgat ttaatgatgg atttaatata gatagtgaat ccattcccat
    30481 taaccttgtt aataaatgaa agctacttgc aaaacttcca catacaccac gtttatcaac
    30541 cagattacca tagactatgt tacaatattt agagtctaca tattttgctt cggttaccaa
    30601 ttttgcagct ctattagctc tttccatctc agatgcattt ctccagtcaa aactatttaa
    30661 aaaattcctg attactgtaa gtgtatcttg agcttgtttg taagaaatcc aatctccatc
    30721 ggctattact tctatagggt caagttttcc aaagcctatt ctctgatatg agctacctga
    30781 caatgctgct gcataaaatc ctagcccttc cataccctta tttatataat aatatttacc
    30841 atctgctcga agctcaactc catttggatt tcctccatag agtaaattaa acttattttt
    30901 ttaaaacata ttgtttaaat cagtacattt atatgttttt tttgttcatc tgttttatca
    30961 aatatattag tctttgaatt ttgtttgtat tcttcagcat ctttatctaa cttttctatt
    31021 ctcgactcaa gtttcattat ttcttcttgt gttaaattta taaaattttt aagcatattt
    31081 tcaagctctt cacgagtttt acctactaaa gataagtcct cagatacttt ctctttttta
    31141 ttagaatcct ctttataatc ctttttttgt tctaactctt ctaatttttc atcatttaat
    31201 atttcttctt caattttttc attagactct ttagtgatta aagattcttt ttcatcattt
    31261 gtatttagat aagttgaatt ttcatctaac attgtacttt tatttttatc ttctataatg
    31321 ctatttttaa tacctatttc tatattagaa aagttattag ttgtttctct tatttctgat
    31381 ttatataagt tcttaattgc ttcatttatt tttttagtat aaacctcttg tctatatttt
    31441 aaatctctaa ttctatcatt aagttcttgc ttttgtttca taatattaga taaataagtg
    31501 tcttttccta cagtttcatt tttcttaacc atactttcat ttattcttgt attatttata
    31561 ttactttcat gtctaaatga atattgactt ctatattgac tagatatttt catttatttc
    31621 acctctctaa aataaattta tgtttataaa aaccaactta acttaattat attttatcat
    31681 caaaagtata catttacaaa tattagttaa tagttttata ggttcgagca ttgttttcaa
    31741 caaaaaattt ttattataaa ttaaaacaat aatttttata aatatcttat ttgtatttta
    31801 taattcatat atttttactt tataaattag caatattgca gttttgctct taagaaacat
    31861 ctctatcata cataagcata tactctatta tgtattagta taaatatgcc ttttcttatc
    31921 ttacataaga cctctttata aaggagacta tcgtaacaaa tatgtataca ttatcacata
    31981 tatatatcat catataaaaa atcaaacttt attaaaaaaa ttaataaatt gctttaaata
    32041 ataccacaaa ccaaatttgc catcaaaatc acattaaagt aacaaattaa tggcaaattt
    32101 aatacattaa tagtatatag actcatagaa tgaacaaaaa aactacactt atcttctaat
    32161 cgtcttattt atttttgaga tatttttaaa tttcttttct ttttttgcta agtattcgct
    32221 tttattgtct gcaaatactg cttcagtttt aagcctacga taggattccc atcttttagg
    32281 cgaaagttct tgatgagcaa tagcttccca gatagcacag cctggttctg aggtgtgagt
    32341 acaattacga aaatgacatt ttccgaaata agcttctata tctgcaaaac ttttatctaa
    32401 accttctgaa acatcccaca ttcccaactc tctcatacct ggtgtgtcaa taacaatacc
    32461 accacctgaa attaaaaata gctctcgtct agtcgtggca tgtcttcctt tatcatcatc
    32521 tatgcgaatt tcctttgtat ttaaaaattc tcctcctagc agacaattaa ttaatgaaga
    32581 ttttccaact cctgaagagc caagtaatgc aacagtacag cctgatttga tatacttaga
    32641 aatctgttta taaccatctg gctctataga tgaggtaact actacatcta cacccaaggc
    32701 tatagaatta actacttgta atttacgatg cacattgtca cataagtctg atttagtaag
    32761 tactactact gggatagctc cactttccca tgttaaagac agatacctct ccaatctatg
    32821 aatgttaaaa tccttattca gtgacatgca caaaaaaaca atgtcaatat tagctgcaac
    32881 cacctgttcc tcatttacct ttccagcagc cttacgcaca aacaagcttt ttctatgaag
    32941 cacatgatga ataatagcat taccattttt attattgcaa cgatccaaca taacgaaatc
    33001 accaactgtg ggaaaatcag attgtatagt agcctcaaaa cgcagttttc ctgaaacctc
    33061 tgcaaacagt acaccattta cacatacagc ttgataaaag ttcttttcct gcgagataat
    33121 tcgagcaagg tataaatcgt gatattccat actttgagta ataaaattcc tatttagacc
    33181 atagtcttgt aaattgattt gtttcatacc attcattctg tttcctcctt ttccaacttt
    33241 tcaatgattc tttctagtgg gaaagggggc tgtgccagtg gttttaatgc aattgacatt
    33301 aatttcactg aattatcatc agctgcaata cgattagaac taagatgtcc acagcgtgta
    33361 caacgatgaa taattgccca ctcaccattt tttctcaccc acactccaat aggttccata
    33421 ttagcatcac aatctgcagc acggtcacca ggaatgatat ctacatgaag actatgtaaa
    33481 caatgtggac aatgatttct atgttgtgta ccagctcctt caggaactac aaggcaacca
    33541 caatttttgc aaataaagtt atccatacag gaattttcct gataataagc tcgttttcta
    33601 tttttataat tcatttttat ttcctccgta tcttgtattt tctacaaaaa aagtccacag
    33661 gtatttatat ctgccttttt atgtggtata catatttacc tacacaaaaa cagaaaaccc
    33721 ctgtggacta gaaaatttag tatcttctat ttcaacataa ttatattcaa aataatactg
    33781 tgtaaaatta ataaaagtgt agcagattaa agcccactac accacaattt aacaaagtaa
    33841 tatgtaatat tattatttgt tgtctaatgt tagttatcta taaaggcaga gtaagacaca
    33901 acaatcaaat gtatcaaaaa tacacttaaa aattctgatt aaacagaacc catatgcgtc
    33961 tccaactatt tatttgttgg ttaccattat atataactct gacatcaggc aagacactcc
    34021 ttcactaata attattatta aaattttatc ataaaatata agtatgttca agtataattt
    34081 aatatattca tatatttatg tttgtctcat tttcttattc tataaaatct agtggtattt
    34141 taaaatttaa tgttcaccta gtattaataa taaaaattaa ttgctattat ttgttttctc
    34201 attttatgcc tattgctcaa tttatctcac ttaaattaat aacaactgtc ttttcataca
    34261 aaacctacaa tcaagttttt ccatatattc tacatgaata gtctattttt tttatataaa
    34321 ataacgttca tatttgtaaa tttatttaat tttcaaataa gtatattgaa taataagcaa
    34381 ttctattgta ttattgtaat tgtagaataa aactaaatcg gcaaaactag agaaatttag
    34441 tgacgcaaag ctatagggac taacgcttat aaaataaact atgagttatg tcagccagtt
    34501 gccaaaaaga gatattcttt ttgtttttat gaaagttttt tagggggata ataatatata
    34561 tgtttagaga taaaatggat agatgtacac atatgttgac tgcttatatt ggtagttcat
    34621 atgattattg tgattttata gatacacaac tagatgattt tatactagag tacggagaaa
    34681 atgtggtaga atcttgtttg catcaagtga tggtattagt aagtaagtat aattaaatag
    34741 atttggtttt ctagagaacc ctttttagtt ttatctactt taaatagcct tatgttagaa
    34801 agctaattaa gatagatttc tagtattcat aattttattt tctatttaaa atacatataa
    34861 taaagatgta aatttgtatc aaataataaa tatgagaact taaattctct tatctatgtg
    34921 aaaataaaca tctcttaaaa tgaaattctg taaacataaa tgatttttta gtttgaagga
    34981 ttagattaac aaaattataa atttgcaaat aagctatatt aaaaaatata ataatttttt
    35041 atataactta ttcttttata acttttaatt ttaaaagagg agaatgtata taagagtatt
    35101 caatgtacta gaaaaaatca aaagaaatat tagaagaaat ggatattgag taatcaaata
    35161 aaagattttg atattacaaa tgatatgttt caagaaagca ttcctatcac aacaaaaact
    35221 attcttgaag acatgccttc aaatgatgaa ttaaatcatg ttttttcaaa aggttgtgaa
    35281 cgaaaaatga aaaagagaaa aattgtatta atcacactac tattaatagg tgttttgtta
    35341 ttaggaagta tcctatataa tcttttttta gtaaaagcag ctaatatttc aatgctaaag
    35401 gaatcttgga attttgatat accaatacct aacaaagaaa ttgaagtatt tgatactcaa
    35461 gatagtatta atggagatgg acaaagttat tttattcaag gattttctga aaagaatttc
    35521 aaaaaagttt ttaatttaaa aggtggtata gttgtaagca aagataatat taatgaaata
    35581 gaaaaatata ttgataaatt taaaagagat tctgttaaca ttaataaaag taataaaaat
    35641 aaaattgaag aagattttaa aaaatataag ttagaagtta aaaaagatga taagtatata
    35701 tataagagaa attatgaaaa ctatgtagtt ttaattataa aaaaagatga acaaaaatta
    35761 tacagtttaa tatggaatca gtaggtacat atgtattatt aagaattata aataataaaa
    35821 ataaatttta gtcaatctac aaaaaccttt taaattgtct ggaaatcacc tcctcatttg
    35881 ttataaaaac atacaacaaa tgaagaggtg attttatggt ttttaaaaaa ataattataa
    35941 gtggatatgt gctttcacat gtttatcaac atttgtaatg cctatatttg ctaatgaatt
    36001 ataatataaa aatattaaat aatattcaac tatagattat gtaaattatc ctatgaaaaa
    36061 aataagttgt ataaaatctg gcaactgtag attgacgatt tcttttaaaa ttacaattat
    36121 aataagtttt atagaattaa aaataaaact ttagagattt ttgataacat tgtagactaa
    36181 atttgccacc gaaattactt tacagtggca aatcggtggc aaatacaata tattattagt
    36241 atataatcta tataaacatt actattgctt gattatctta gctacagttt caacttgctc
    36301 atcattttcc aaacttatat taagatcttc atcaatgata ggtagcttaa aagtaatgga
    36361 ttttagccat tgtccattag gctgcttttc ttcataaatt tgaatttctg aaatgagtgc
    36421 ttctattaac tgcctgcgtt caacatcgtt catgacttta taaagcttgt caaaataaat
    36481 caatacttta tatatgttat caccagtaag tttctcaacc tctatcgttt ctttttttgc
    36541 tttagcttct attaactgac tttctaattc ctcaatttta tcgtacatac gataaagcct
    36601 atcatctaaa tcattttttc ttctcttata atgtttatcc tctacatcta aattatctat
    36661 ttcctcaata agcttatact ttgtagaatg actttttctt agttcatttt ggtaattatc
    36721 tatctcattt tcaatagcag atgtatcaac cttcatgtta attttttctt gtatcataga
    36781 tgcaaattta gggttgctta ctaacttgat tattacctca gcaacggcat catctaacaa
    36841 ttcttctcta atttgtttat tataggtaca tttatgtcct ctattcataa gtctatgctt
    36901 acaaccatag taatagaagt ctttatactt cgtcccatct tttttatatt ttatagattt
    36961 attcccaaac attccagctc cacatatcgg acactttact attcctgata ataagtgtgt
    37021 cctcatgttc ttgcccttat ttacatgttc atacttttta gcttgtgctt tcagtttaac
    37081 ttgtgcagcc tgccacaatt catctgggat tattgcttca tgaatgcctt ctgctactaa
    37141 ataatcgtcc tgctctactt gtctgtattc attccttgta ccatgaactt tttctaaagt
    37201 tcttcttcca aatgctattt tcccgttata cacaggattc tttaatattt ttcttataag
    37261 acctgcgtca aacaatggat ttttcccatt ttgtcttggt attttcctta taccatgatt
    37321 ttctaaatat ttagaaagac cattagctcc aatacttgta tttacatatt gatcaaaaat
    37381 agttcttatt gcaattgctt cttcctcatt tattatcaat ttcccatcaa taagttgata
    37441 accatacgga gcaaatccac cattccattt accctctttt gccttttgaa tgcgaccttc
    37501 cattgtttgg acacgaatgt tttctctttc tatttcagcc actgccgata aaacagaaat
    37561 catcaattta cccgcatctt tagatgaatc aattccatct tcaacgcaaa taagatttac
    37621 tccaaaatcc tgcattattt gtaaagtcga aagtacatca gcagcatttc ttgcaaatct
    37681 cgatagttta aatacaagaa cgaaagacac tccatccttt ccggatttta tatcttccat
    37741 catacgagta aactgaactc taccttctat agattttcca gacttacctg catcttcgta
    37801 ttcaccaaca atctcataat cattatagag agcaaaagcc ttcattcttg atttttgtgc
    37861 ctctaaagaa taaccatcta tctgtatgga tgtagatact cttgtataga gatatacttt
    37921 tattttttct tttgacatag cattaacctc aatatcctta ttatatattt atatattttt
    37981 accaataaag gtttggactt taatctcaag tatattatag cacttttatt tctctttctc
    38041 aatccgtgct tttagctata tcaaatttat tcttatcctc tgtatttttt actggagtag
    38101 gatttggaag attctctaaa tctaaaactc cagcatattt tgtaatcaga tttgctatca
    38161 aatcagccaa tccattccag tcattatcca ctaatacacc tcctccactt taaattcttt
    38221 ataaccaaat attatttttc ttactaagtt ttatgacatt ggtaggtgca ttggctgcta
    38281 cataggaatc tcacctccgc cccttgtttc agacgaggca gcttaaacta ttgaagtatc
    38341 attatcacca cttacatcat cgaaataagc tgccacgctt atcttttatg tattcctatc
    38401 tatcgctcat tttcttctaa cctcggcatt atgccggtat tcatttgaac cgattttcat
    38461 cagcagaaaa gtcttggcgt aggtcataac tctcagtaag tagataaagt cctaccttgg
    38521 tctattcagt tgtcaaagat caatatttga aagggactgt tttctttaca ttttcctatt
    38581 tgccataagc aggcgtatct cctactcaag aaagtaaagg aggtcaaact ccccttcact
    38641 ttacataagg aaaatttgcc ccctttggtt accaaagttt taaagttctt cgataaattt
    38701 tttcagcttt tcaagaattt tgtttcttct tttgattaaa gccggatgtg taatactttt
    38761 gagctttgct actgaacgaa cagtttcatc attgaaatac aagcgttcaa taatatctct
    38821 ttcttctgca ttgagccttg ttatagcact tcttactgct tcaatcatca tctgtgtttc
    38881 aacaatcttt tctacatcaa cactttcatc aacaatatta tctgtaaagt gtccgtcatg
    38941 atccaatgct gaaaaaaaga gcaagtggtt tttcctgtcc acctgctcta aatacttctc
    39001 gtgttctttt tctcgccagt agactatata tatatcttca ctgactttta ccttttgtcc
    39061 tctgatataa agataatact cttttgccat aaagtttcct ccatctcttt tttatctgct
    39121 tgtttttcag ataaaaaagg aggacttctg catcttggca taagaagtcc tctgaaatga
    39181 aagaataaaa atatttcttt atatgaactt gattgtttca attcgcacct gaaacaatca
    39241 tctactatac atattataaa aaagaggaat gtattgaatt ctaaatattt ctaacattaa
    39301 acgtttagat gcttccatat ttatttcctc cattttatca ataatctaaa taaccatcat
    39361 attcatctac tacttatata attgagtttt attaaacttt ttaagtttct attctatcaa
    39421 atatttaaac agtctctgca tccgaaaaga ctaactcata tagttttact aacaatattt
    39481 tcattagcgt gttcaaatcc tgatttcttg tatcaattat tttctgttca ctttcaataa
    39541 gaaaaaagcc tttacttcca tggctaataa taagtctcta tttttcaata actattgcaa
    39601 aattatatct tgtttaagaa aatattttaa ttttaaagat aaaaaattct tcatcctgca
    39661 atgctttata ttctatattg taattattca gaatattact tacaatatat aaacctaatc
    39721 cattactatt ttccttattt aaatcaaatt taacatcaaa tattttatcc atattcgaaa
    39781 ttttattgtt accgtatgaa ttctctatat ataaccaatc attaactatc ccaatattaa
    39841 ttaccccatt tacatcagta tattttaccg cattactaat caaattagat agaataatct
    39901 ttaaagctgt ttttcctata taaacattct catctaatat ataattattg acagttattt
    39961 tcttttgatt tgctaatatt tcatactttt ttaatatgtc ttctaatgta tcatttattt
    40021 tcaaatattc ttcatcatta ttcaaatttt ctatagaatg aactgataat atttgagaaa
    40081 tattttttgt taaactatca acgatttcaa tacattcatt aatataaata tctctttctt
    40141 tatattttcc aatattgtat ttcatgtttt ccagtattat tttaagacta gcaagaggag
    40201 ttttaagttc atgggatgca cctttaaaaa agtcatattt taacttttct aattttaaaa
    40261 tttctttatt tttaaattcc aaatcgtcaa ttgttcttaa taaagtagaa tacaaatcat
    40321 taatttgttg ttttaattct ccaacttcat cattagagct aacttttaaa cgcgtttttt
    40381 tatcaagttt catcatttta tcagtaacaa tttttatttc ttgtatatta ttttttattg
    40441 attttgcata aattaaagaa ataatagcag aaaataaaat tgatattaat aaagaatatg
    40501 gtaaaaattt aaggcttaaa tctttcgcat ctttttgcat atcagctgta gaaacaaatt
    40561 gtagatttgt ttttttacca tcattaagct ttatttctct ttcttcaatt atcaaagaat
    40621 tactatcact ttctaaatta acatttatat tatctttgat ttgtatttca ttcttattat
    40681 ttttttcttt tataaatgct tttatttcac tactcttaga ataaagctcc aaagtttgtt
    40741 ctatatattt tatttctttt ccattcatat tactagaaat ttcatttgcc atattatgaa
    40801 tcttttcttt tctcgtctcc aaatatgttt taggaaagat aaaaaaaact aatgaatgaa
    40861 ctaatataat tattattcca agaacagaaa atatttgtat gaacattttt ggaaatatct
    40921 ttaatttttt cattttctct ccaatttata tcctacattt cttatagtag ttatacagtc
    40981 taattgtaat ttttttctaa gttcttttat atatacatct attactcgat cataaggagt
    41041 ttcttcgcta tctttccata cataatcaat aatttgcatt cttgttaaca cttgtccatt
    41101 attatccaat aaacatttta atacttctag ttcttttgca tttacatcta tttcttcacc
    41161 atttatttta gctgtatagc tattaaaatt aaccgataga tcattatatt caaacttctc
    41221 taaatgtcca taattcttct taattaaaga atctattcta gcctttaaga ccggcaatga
    41281 aaatggcttt tctacatatc cgtctactaa attagtaaat gcatcaattt tatattcttc
    41341 atcactaaat gcagtcaaga ttagaattgg taaattgctt ttctttctaa tttctttcaa
    41401 cacttctaaa ccatttataa aaggtatctg aatgtctaag ataaccaaat ttatatcgct
    41461 attaaatttt gacaaggctt ctcttccatc tttagcttga ataacagtat atccaaattc
    41521 tgaaagatat tcacttattc cctctcttat catattatca tcttcaacag ttaatatttt
    41581 catatatacc tccacttaag cctctacact tatattatac agcatattat ttgatattta
    41641 aaagccaaaa aatttttggt gctaaaaagc accgaaaatt ttaattattg tcaattaata
    41701 attcttttgg attccttctt aatatattga atgaagaaat aatcaatgat acaagaagta
    41761 ctaaactcat aaatataact acataaatta tgaatttagg taatacattt atatctaaac
    41821 ttgataatgt cttgttaaat ccttcagctt ctgccccacc acctaattgg ctagatgcag
    41881 attgtctagc tatttgttta gctatatcac cagtaacctt attcaatata ttattcccaa
    41941 gcttatcagc tgtatattga gctaagaaat aagaaccaac gaatgcgggg attgatataa
    42001 ataccatctc aattaggaat tgaccaaaaa tttctaattt tgatatacct aatgatagta
    42061 atactgctat ttctttcttt ctagcattca tccataagaa taataataat gaaactacaa
    42121 ctcctgcaaa tattaatgag ccaacaaata atttatttga aattgagtag atacctgata
    42181 tagattgttg taatgcaggg taatttgatg aacttttaat caaattatat tctctccaat
    42241 ttatatctaa tttcccaaga tcttttatta cactatcaag attcttatca ccttttacaa
    42301 agaatgttgc atcttggtat acagctgtat cttctgtatt accataaact ttagcagctg
    42361 tatgaacatc agtgattaat gtattttcgt atagttcttg tgctgcactt actccaccgc
    42421 tattatgccc atcgaataga cctttaattt ctacttctac tgtttcatct gcacctttct
    42481 cattatcagc atcaaataaa ttagatttta tttttatctt atctccaact ttaagattat
    42541 ttttttcagc taaatcttta tgcattaaga ttttattttt atcttcattt tctaaatgct
    42601 ttccttctac taatttatat gcttctgata caaattttgt ttcttttgat gagtcgttaa
    42661 ccccagttaa cataactgtt cttttaaaat tcttcgctct ttcaggtgat tgattcgcaa
    42721 gagtctcttg agtttcaata atatcataat caactaaatc tgcaacactg tttattcttt
    42781 ttacatagga gtctatacta tctgtttgaa atatcttttt aatatcttca ccttttacat
    42841 ttcccccacc tctaggtgtt cctggattta cttgtctatt tatctccata gaaaaactat
    42901 ttgttatatt agcaaatgtt tcttttgaag ctctgtccgt agcatcttta atagataaac
    42961 taatgagact taaagttgac atagataaaa taactaatat aataattaat gattttaagc
    43021 tttttctagt tacataagca aatgcatttt ttatcattat tcaacctcca aattcatttt
    43081 atttactttt ttcaactttt taccacttag ttctaaaatg atatccgcag aatctgctac
    43141 ttccttacta tgtgttacaa ctattacaca tttatttcta tctttagcta atgtctttaa
    43201 tatattaatt atttctccag cagtaacact gtctagatta ccagtaggct catcagctag
    43261 tattattgga gcatctgata ccaatgctct agcaatagct actctttgtt gctgtccacc
    43321 agataatttc ataacatttc tttttatttg ttttttatct aaacctagtt caaacaagat
    43381 actttcatct gctgatttat ttactaatct aatattttca attggtgata aataatctat
    43441 taaattatag ttttgaaata ctaaagatat attatttttt ctatgattac tatatccttt
    43501 cttttgtata tcttcattct taaacaatat ttttcctgtt tgaggtttat caagtccagc
    43561 aagtaaggaa agaagtgtag attttcctgt tcctgacttt cctactatcg cataaaactt
    43621 cccaagttca aatttttgat ttactcctga caaaactttt tctttagaat ttgcataact
    43681 atatgctaca ttctttattt ctaatatatc cattattttc tcctaactta tttttgataa
    43741 tatttcttta ggcttcttga ttaatattaa tgaagaagca aatacaactg ataaaacaat
    43801 aatacttatt aatattaaat aactttgtcc aagtgttgtt atatttaaca taaaactact
    43861 attatttatt aaacttccac cggaaatcat tgagtcctct gagttaatga atccatctac
    43921 aattactttt agtaatacat ttcctaaaaa taaggaagat attatacttg gtatcgatat
    43981 gaatattaac tcgaatataa attgcattat aatttgtatc ttagatgttc caatagataa
    44041 aaatatacct atttcataaa ttctttctct taaccataga atcaagatta atgaaagaac
    44101 aaccatccca cctaacataa tagaataagt cattattttt attatatgtt ttattccact
    44161 cactgactct aaagactctt caaacgcatt agaatctttt tcaacaaaat actttgactc
    44221 atcaatttta agctctttca atttgtttaa ggctaagtct gtagattctg cactaccaga
    44281 atacattaaa attttatttg cgattttatt attttctgat ttatttaata tctcttggct
    44341 tgttgaataa tctacaaaca ccatattttc actaaaatca gaagataatc ctgtatatgt
    44401 ttcctgtttt ttaccagaaa agatccctat aattttaaat ttatgacttt ttatttttcc
    44461 acttttttca atatctagta attcaagatc aacttcatca cctaatttta gattgttttg
    44521 tttagcaaat tcttcatgaa caataattga attcttatca ttttctccta tatttttgcc
    44581 ttctttaatt gtaaatactc cactactaaa taaaatattt cttttagtat tatttgtagc
    44641 ttcgagtgaa acaacattct taaattcgtc agataaatct tctctattta ttctttgttc
    44701 tccgctaact actttagcat cttttagttt tgctaatcca tcatattgaa ttattttttc
    44761 ttcaatttct tttaattttt caatatcttt aaattgatta acattaaaat atttaccatc
    44821 tttttttgtt attgatattg aagaattaga actttcatat aaagcctttt ctatttcatt
    44881 gcttgatttc attattgtta aacaagaata caagcaagaa agaactatag ttaatatgat
    44941 aaaaattatt aaagttctat ttctctttct tgtaatatat gctatagcat tttttatcac
    45001 tttcctaact actcctctct attttcttac tccataacta attgcatcca ctggacaagc
    45061 atttttacat cgtccacatc tgatacactc cagatgattg caattctcaa ctggatctat
    45121 attcatttgg caaacttttt tacattttcc acaattaata cacttatcct tatccaatct
    45181 atatctaaat attgaaatag ggttaaaaat tgagtaaata gctccaagtg gacatatata
    45241 tttacaaaaa ggtctatata taattataga aagtaacaaa gtaactatta gaatgattcc
    45301 tttccaataa tacaagaaac ctatcgcatt tctcatactt ttatttaata aaacaagtgg
    45361 taatcctcct tccagcatac caatcggaca aataagttta caaaaatacg gagaaccctg
    45421 acctaaaata tcaaccaaaa ataaaggtaa tattattaca aatacaagta atattatgta
    45481 tttcaatttt ctcaaatgtt tatcaaactt aaatgtttca acttttttaa aaaagggaat
    45541 cttatgtagc aaatcttgaa tcaatccaaa tggacacagc catccacaaa caaatcttcc
    45601 caccaatgct cctataaaaa acaaaatccc aactatataa taactaatct tatattttga
    45661 atttccaatt actgcctgta gtgatcctat tggacaagaa ccttttgctc ccgggcatga
    45721 ataacaattc atacctggaa cacaaatttt ctttaaattc ccaccgtaga ttttaccagt
    45781 cttaaaccct tcaaagtaag aattagtaat taaaaaccaa acggattgaa ataaatgcct
    45841 aaaacgatct cttattttat atttatcttt ttttgtacta ccatttataa tatttttaat
    45901 tctatccaat tccaatacac tccatacaaa ttcttatcgc cttatccaag acaactttag
    45961 tttctccatt actatgacca tagtaaatca tcgccatact aataaagata attaataaag
    46021 acaaggcacg gctttttaaa aacttattaa ccatatacca atcaccgctt tacttttatt
    46081 tattttttat tttttccaat tctttttcaa ttacctgctt ccattccttt gaactctttg
    46141 ccccagaata agtatcacct acaatatttc cattactatc aacaaagaaa gtctctggca
    46201 tagcctgtat accattcaat ctaccattaa agtttgtctt atctggcatt aagaaaggat
    46261 atgaagcctt tgtcttttca tgtattaact ttgacttttc aattgcttcc ttgttttcac
    46321 cgttatcatc aacagtatct gtaacaactc caacgatatt tacacccttg cttttcattt
    46381 cattctgaac ctcaaccaaa tcaggaattt cctttacaca agctgtacac caagttgcaa
    46441 atacatttac catagtaaga tcatacttct caaaatcttt acttgtaaaa tccttgccat
    46501 ttatgtcctt tgttgatagt ttacgtaaat ctttaaccga ttctttgtta aatgcttctg
    46561 tattttctaa atcagttttt tctgatagca caaaaccatt tttaggacgt tcttttttat
    46621 ctataatttg aatctcagtt ctttttaatt catccagaag attactttca gctccgctat
    46681 ttgtgcttaa atagcaatcg tattttccat cacttgaaac tcctatttta gtatgagtat
    46741 cacattttgt aattttagat attttttctt ctgatgtatt tttttcgaat ataccaatag
    46801 tcccaattct ttcaagctca ttttgccaat ttttatatcc atcgcccatc ttttctataa
    46861 ctgcattctt ttgttcttct gtcatttttt caaatgtcaa aatagcatac tttagttctt
    46921 tatctatagg actttgatca tctaacatcg ctatcttttt atcatccata tactttttaa
    46981 atttgtctga aagtttaaat ttaagaccta aatattcata aacatattct ttttttgttt
    47041 ttaaagtata atctgatggc ttaaatgttt catttttatc cttctcatta gttgacatac
    47101 ctgcctcttc agaacttata gattgtcctt ctttaatttt attgctttca ttactttttt
    47161 tacacccaac tgtacttaag ctcaaacata acgtaagtaa taggcatgct cctcttgata
    47221 ctattttttt cataaatttt tcctccttta ttcctccttt atttttacac aatagcagtt
    47281 tataactact ttcaataata ttctacacac cttttatgaa acgttgatga aatataattt
    47341 tttatttttc caaactatgg tataataata taaatattat gcttaaagtt gttcttacac
    47401 gattagtata tgatcgatta gtatatgagc aagcacagta agtgtacgga cacttacgaa
    47461 aaaattgatg aagcagccct ctgggatatg cttctttttt tatcaatttt taacttgtta
    47521 gggtataccc taagaccccg aaatacattc aaaggaggat ttacctatgg caaatagaat
    47581 acgaaatgaa agactggaaa ttaaactaac tgaagaagaa aaggctcttt ttgaggagaa
    47641 acgaaagctc gcaaggtgca gaaatatgag ccactttatc cgcaaatgcg ttttggaaaa
    47701 ggaaatatat caagtggatt tagaaccgtt tagagattta cagggcttac tgtccaatgc
    47761 tacaagcaac atcaatcaga ttgcaaagcg tgtaaattcc accggcataa tctataagga
    47821 cgatataaac gatatgaaaa agcagattga atatttctca aaagagttgt ggcaaataca
    47881 ttctctgctt cttaacagaa cttctggagg tgattaaatc ttatggctat aacaaaaata
    47941 catcctataa aatcaaccct taatcttgcc atttcatata ttgttaatgg aaaaaaaaca
    48001 gatgagcaaa tcttagtaag cactcataaa tgccatcaag aaactgctca tacccagttt
    48061 ttaagaacac gaaatgatgt tggaacaaac ggaactgttc ttgccagaca ccttattcaa
    48121 tcctttttac ccggagaagc aagtcctaaa atggcacatc aaatcggtct tgaactgtgt
    48181 aaaaagatat taaaggacga gtacgaattt gtcttatcta cccacataga taaagggcat
    48241 atccacaacc atatcatctt caataatgtg aatatggtaa caggcaagtg ctatcaatcc
    48301 aacaagaaaa gctaccacaa aatcaggtat caaagcgata agctatgcaa agaaaacaac
    48361 ctttctgtga ttgatgagtt ttacgaaagc tataagagaa agtacaaaac aaatggcaag
    48421 tcatggtatg aaaatgagca atctaagaga ggtacttctt ggaaaagcag acttcaattt
    48481 gacattgatc gtcttataaa acagtctaag tattgggaag aatttctaaa aaaaatggcg
    48541 gagcttggtt atgaaataaa gtatgggaaa cacatagcct ttaaaccaaa agataagaca
    48601 agatttacaa gagctaaaac gattggtgag gactatacag aagaaagatt aaaagagcgt
    48661 attacagaaa atcaatctat tacaactcca cctgtcaaaa gacgaatcgg aaatatcatc
    48721 aatatgaatg ccaatgccaa agtgaaagag agcaaaggct atgaatattg ggcaaccaaa
    48781 cataacttaa atacaatggc tgagtcagtt atttttatca gagaacatgg cattaactcc
    48841 attaagcagc ttgataaata cattcaaaaa agtgctgaag aaagacaaga cttacaagat
    48901 aaaatgaaag aaattgacaa ggatatgcag ctactttccg atacaatgga gcaggttcat
    48961 actgttaaaa aatatcgagc ctactacaaa gaatataaag caaacccttc cgataaagca
    49021 ttttttgagg agcataaggc tgaaattaca cactatgaaa tagctctttc aaagctaaaa
    49081 aaatcctatt caaagctgcc gaattcaaag gatattttag ataaacttaa taaactgcaa
    49141 gaaaaaaaga atacccttat tcaagagtat tcttctacaa aatctactat ggacgaactt
    49201 tatcaaatac gaaagaacta tggaatttac atgggtaagg agatggaacg ataactctaa
    49261 tattatatag ctttcttatt tttataatat taaattgaaa tgcctatcaa tgatgcaagc
    49321 atttttatac ctaaagctaa atcaggaatt aaagctacgg aagtagtgat aaaatgcata
    49381 ctttttaaac aagtagtcaa tacttctttc ttcggatgct tctgcttaat ttcatttttt
    49441 atattatcta aattctgatt aagtattgat ttggagttat catcctccat acctttaatt
    49501 aagtcttcta cattgttaat tgccttgatt acttcttcag tattaaattt attttcttgg
    49561 tcagcgttaa tcgtgcttcc gtgttccgca atattgactt gaactccaga actattaaca
    49621 ttgatattat atagagcatt attttcatcg taccccatat cggtagaaat atctttcata
    49681 taattttcaa cctcaagtac aaacggatag accattctat cgccaaacgc ctttgccata
    49741 tcttgatatt tattactgcc agcataatac cagccaaaag tatatgtagg tagattattt
    49801 cctgttataa aggaaaatgc tctatacagt agatacgtcc ttttattact atcattgcca
    49861 agattcaaaa ctttacgtcc ataagaatta cttatcgtat ttaataagtc atctaagcca
    49921 tcaacatcat attctaaact atgcaaatac tcttttatca acaatgtttg ctctatataa
    49981 tttatcattt cttccaaatt tgcattctgt tctccataat atgaattcat aacatttgaa
    50041 gctaatatcc taaattttct actgattttt ctaagttctt ttttactaat ctccatctat
    50101 catctctcca caaaacgggc aataactacc ttctaatttt tttatactac ttattctagc
    50161 ggttttgcca caacacaaat atttcttttc ttcataatct ccagtttttc ttcctatcgg
    50221 aagttctgct tcctttttaa tctcttttcc acgtttaaac tttatacttt tactattcct
    50281 aaaacttttt tcaagattct ttgaaaaatc atttagcatt tcagcaactt gattttcaac
    50341 tattcgttct gctaattcat aaatatcatc gtctaaataa ttctcgtgtg ttaaaccaca
    50401 attaggacac caaatatcta ttgtgctttc agcctcaata tcttccaccg ttaacataaa
    50461 tttttcacta caacttggac attttaattg aacatatccc tcttcatccg ctggaacaga
    50521 aatttcaaat tttatatcat tagccattta aatttcatct cctcacaata aaagttataa
    50581 tttcaccact ggtagactac aaggtcgtgc atctttacgt acaataacaa cactattctc
    50641 agcacgtgta acagcaacat ataatctagc cttactttgt tcttttagag atgtgttatt
    50701 gttaataatc caatcccaca tcggttgagt cggatatata agtactcgtt ggaattccaa
    50761 gccttttgat tctccaaaat tataatatgg atattcatta ttgacggatg tccttttatt
    50821 ttctctcaac tgcattgcat taaatttctg caaatacttc tctacatctg ctttatcaat
    50881 tatcataaca ccatctgatt catcttcagc tctacgcaca aaatttgtag atgttctctc
    50941 tggatacaga ctattcgcaa atttacatat aatatcattg tttctataag tacaattaag
    51001 tgtcgtttca tcaattctta catctaattt tctgcactca ttttttaaaa actcatctat
    51061 tttcccacaa ctatattttt tatatttttt tgatgagtga gttgaatatg tgcattgtct
    51121 aggatccccg accattatca cttcaattct tgaagctatt aaacacttta atatttccaa
    51181 atcatacccc accatatctt ggacttcatc aacatatata cagtcataca ttccactgat
    51241 tctttcaaaa acttttccat tacatttatc atttaactct acaacacact ctgataattt
    51301 atcagtatat accctgttat ctttggcaaa atatttgttg gatgttttct ttacgtacgt
    51361 attgttctgt ccatttacaa atataattcc ttcaattcgt tccttaaatc tacttccttg
    51421 ataaggtcta ataccatctt ttaacaaaaa agaaaaccat gtagaaactg taatattatt
    51481 aggaattaca ccaactttat tcttaattcg gctaattatt tgttgctcat ttgtaatagt
    51541 atatgttagg attagtattt ttttatgagt attaagagaa tcctctataa tttttcttgt
    51601 ttttccagat ccagcagcag ctatatataa tttcccactc atattagaat accctccttt
    51661 atatattgtg gaaattctat agctttatca ctttcaaaaa tctttaaagc aacttctgtt
    51721 ttatgcccct tcatatattt aagtaaatca tctggatctt catatgattt attcaatatc
    51781 tcgtttaaaa tagacatgga attcgatcta tatatacacg gttccaaagt attatagttg
    51841 taattttcca aagaaccatt atattcatgg gtactatcat caaaatatat atttatattc
    51901 tcacaacaat tatctcctaa ataatcgcta tattttctat ttagtgcatc aatatttcca
    51961 tcattatcgg ttatcactga cacacgtaat tctagcaatt ttgcgatttc caaaaatctt
    52021 aaaaaagaaa ttccaaccga tattatatct attccatcat taataggcaa tttaccatta
    52081 tgagagtcca tatatgctct ttgaacaatt agttcgtccg aatcaccttc gactaaaatt
    52141 gctttatttg ataataataa tcgtaacgta tcataacctg caattctttt aaaaaataaa
    52201 tttgtttcat ttgataaatc acctagccgt agtgtttttc ctcgatttag taaaattaaa
    52261 ttttcaagtc ctaatttatt tgatacaaaa ctactatgcg tagtaactat tatctgtttt
    52321 tcttttactg actcatttac tttatctagg agaatattta agtttgaata tgacaaatgg
    52381 cattcaggtt cttctaaaag cacaatctgc ttattttcta ttttatgatc acttaatgcc
    52441 aattgtgttt taacaataca ttgtgtacct ttaccaatgt tattatatgg tatttcattt
    52501 aattgggtta ccaagctgct ttcccatgaa gttttcgtac cgaaatctac agaaattgtc
    52561 aattcgttat ttgatgtttc cgttaatttt ctatttatat tagcaatatt ctcatctcta
    52621 gaaaattgtt ctttcataag cctatgcgct tgcgatatat taataatttc attatcatct
    52681 aacagattct ttactattct cgatatgtat atatctgacc cactggtagg agtatagctt
    52741 gtcgtatcaa tcattgcaga cttaattgga atgctccttg cagttatatt ttctctggca
    52801 aaagacatcc aacttacctc ataatattca attggcaacg atgttatctt gttcttacaa
    52861 agcattttat actcattgct atatttttca tcaaaactaa ttgataaaca aatcccaggg
    52921 gtgtctttag ttttttcaga atttccatca cctaaaaaac ttggcatttc tgcatcaaaa
    52981 tacgcttcaa taattatttt aggaggttct acattcactc cttcgttgac ttctctaata
    53041 tagttttcca ctatattctt attgaaaagg tactgagtaa gttcattcct aatatttttc
    53101 ccatgataag ttccagttaa aaccagatta atagcttcca aaattgtaga tttacctgtt
    53161 ccattattgc caactaatat attaatccca ttttcaaaat caactataaa ccaatctgaa
    53221 aagcatttaa aattctttat ttttaatttc ctaattgaca ttttatcccc cttctttatc
    53281 taatataaaa atcatgattt tagaatataa atattgataa ctatataaat acagttatga
    53341 gtttcctgtt taatcacaat cataaatttt ttatgctaca tcccttaata ttttttcaag
    53401 caataattta acaataagtt ttatgatcct ctagctcctg aaaataaatc tatgactgta
    53461 aacttagact cccattctcc ttacatcttc aataattacg cactccataa tatcttcaat
    53521 atcacaatcc aaagcattac aaattctaag caaaacatcc gtagttacat tctgtccatt
    53581 cttcattttg taaaatgtac ttttactcac ttttgccttt tccatcaatt cattatttgt
    53641 catatctaaa tcaatgagtt ttttgaacaa tcttttataa ctaaaaaccc tcattcttat
    53701 cctccgttca agaaaactat atctagtata ttataccaca aaatatactt ttttcataaa
    53761 tatattctct ttaatcgaac ttgcataaat aaaaaagagc cggtgcagtc ctaagaccac
    53821 accgaccgta aatttatctc tcagcttctt tgcttgcttc tttcttttct ttcggttttt
    53881 ccttatcttc agcctgatat tttttgatag ctccaagtat agattctttc ttttcttcct
    53941 gtcctttcat ctgttccttt gcctttaaca gttttgaaga aagtatcctg atattgctat
    54001 gctccttgcc gttatcatca atggaagttc tgatctgccc aaagagtttg acaaaatctc
    54061 cctgcttaaa gtcctttgga atatcactct tttctccata aacggagcag ttgtgatata
    54121 acttatttcc ctcatcatct ttagatacta cggagaagtt tgctacctta aaggtttctc
    54181 cgttcttatt ttccctttca attacatcaa cttctccaac gatatttccg acaatattga
    54241 taagattatc cttttcttcc cgaacataaa gcaggtcttt tatctgcccc tgtcccctta
    54301 aatcctcaat catatagtca aactcctcat gcagcaaatt aaggctatca ttgtccatat
    54361 aagcgtcata tagcttatct aaagcacttt catcattgat acccttttcc atgcttataa
    54421 tcgctttaac aaagtcttta tgattatcac ttaacatatc ttcaactcta tctctcattg
    54481 ttttgtaatc catgttttta tctcctttca tggtaaaagg gaggttgccc tccctttatc
    54541 ttaaaaattc ctgctctttt attttttgtt tttcttctgt tttactttct tcctgatagg
    54601 ctcttatctg tcctaagata gacggcttat catctgattt ttgtgtggtt tcttctttgc
    54661 tatgaagatt gtcctccaca tcataagttg actcaaaata atcactgtcc ttaaaatcac
    54721 tatcatatct atccggaata ccgtcattat caaggtcttt tgcaaacgga tcatagaagt
    54781 taccctcatc gtcaatatca agtcccgttg ctactcttaa atcttcagaa tcaacataaa
    54841 ccaaatcact aaatgtagat aactcaattt catttttcat atttcttaga gcttcatttt
    54901 ctcccttatt ttcataatca aagctctctg ttttaatagg cgtatcatca atgtactgtg
    54961 tccaagtttt ctcctctaaa ttaagctcat attgaatacc atgtctttca tccggtgtat
    55021 tggtataggc gataccgata tgctttaagt caggatatag agtatgaaac tcatcataac
    55081 tgtgattttc ttcatactct ctgttacaga agtcaatgat tgctcttttt acatcttcca
    55141 caagaggatt atcatttttc ttttcttcca cctctcccat atcgagcagc ttatttaact
    55201 ctgcaagtct taatacctta gttttcaact catctgcctt ttcaaaaggc ttttttaatt
    55261 cctctttggc attttcaagc tgttcttttg tacttatgag cttttcttca agcatattta
    55321 gtttctccgg cattttctca agggcattat ccagtcttgt gatattaccg tccgcacttg
    55381 ttccaagctc tcctaaatgc tttgcaacac cgtttaagct gaaattatga gaattagtaa
    55441 agaagttata gcttacctct aaatccatat ttctatactt tcctataacc ttgctttcat
    55501 tgatttttac ctttgaaata gcttcaagta atctttctcc ggctaatttc ttatcggtaa
    55561 ttttttctcc cgcaatggta atagaagtaa acttttcttc accttccgct ttaggctcta
    55621 cattggatat atcttttttg acagcttcta tgagcttttc tgttcttgcg atttcttcag
    55681 gatagttttt tgccacctta tcctctaatc tgtaacggtt agacttatag tttgcttcaa
    55741 gcattttaag ttttgtaacc tcattatcca aatccatctt ttctttaatc tttggatcac
    55801 ccgttgccaa cgctttaatt tcggcgtaat ttaagctgct ttcgtccaca tcttctgcca
    55861 cacgaacagg agtcttactg gtcataatct gtgaaatgaa cttttgctta ttctctatcg
    55921 tctgccaaag gtaggcatca aaggtattct ctgtaacata acgatagata tttaccttct
    55981 cattttcatt tccctgcctt acaattctac ccgcacgctg ttcaagatca gctggtctcc
    56041 aaggcacatc caaatcatga agtgcaatca gtttattttg cacattcgtt ccggctccca
    56101 tcttctgcgt tgaacccatt aagatacgaa cttcgccttt tcttaccttt gcaaagagtt
    56161 catccttttg cttatcagaa ttcgcttcat ggataaaggc gatttcttct ttcggtattc
    56221 ccattgctac aagtttttct ctaatatcat catagatatt aaattctcca tctccttttg
    56281 gagtagacat atcggagaaa agtagctgtg ttgacctatt ttcttttgtc ttatcccaaa
    56341 tagcaaatac attttttacg catacattta ctttactatc agggttatca ggaagtaggg
    56401 gattgattaa acgctgatct aaggcaagtt tcttaccgtc attggtaatc ttaagcatat
    56461 tatcaacatc cggctctaca accctatttc tgacatcatc cgctctttca gaaaggctct
    56521 ttaggatttc cttttgttct tcagaaggct cagttttaat aacttcataa ttagcttcag
    56581 gtgtaggaag gttaagcata tccgcagtct gaatatctgc tacttccttg aacatactca
    56641 ttagttcagg caagttatag aactttgaaa atctcgtttt taccctatat cctgttcctt
    56701 caggagatag ttcaaaggag ctttgtgttt ctccaaaagt ggaagcccaa gaatcaaaat
    56761 gctctaagtg atttttcttt aaactctcat actgaagata cctttgcatt gtataaagct
    56821 ctgtcattga gttacttaca ggtgttcctg tggcaaaaac tatgcctttt cctcctgtca
    56881 tttcatccat atatctgcat ttcataaaca tatcggagga cttaaaggct tctgactgcc
    56941 cgatacctgc aacatttctc attttggtat agagataaag gttcttgtaa ttatgtgcct
    57001 cgtcaacaaa gagcatatca actcccagtt cctcaaaggt aattacatcg tctttcttaa
    57061 aatcatcatt taatttctca agccttgttt ccagtttttt ctttgtcttt tcaagctgtt
    57121 ttactgtaaa gttctgattt ctgtcatgct tgtattcttc tacatagttt acgatttcat
    57181 taatctgatc ttggatgtgc ttttcctgat attccttact catcgggatt ttttcaaact
    57241 gcgtatgccc gataacaacc gcatcatatt cccctgtggc aatctttccg ataaatctct
    57301 ttctgttctt cggttcaaag tcttttttat cagccaccat aatattagcc gacggatata
    57361 gctgcataaa ttcacgaccg atttgtcctg ttaagtgatt tggaacaaca aacaaagact
    57421 tactgcacat tccaagtctt ttactttcca ttgcggaagc taccatctca aaggtctttc
    57481 cactgcctac cacatgagca agcaatgtgt ttcctccata aagacttctt gctatggcat
    57541 ttctttgatg aggtcttaaa tcaatttctg tattcattcc ctcaaaagaa agattgcttc
    57601 catcatattc tctgtttcgg attgagttaa aacgctcatt atacagtttt acaagacggt
    57661 ttcttctttc ctgatcgtta aatatccagt tcttaaattc ttcttttaat agctcctgct
    57721 tttgtcctgc aagcatggtt tcttttttat ttaagacaga agttttagaa ccgtccggat
    57781 ttataatctg gtcaaatacc tttgtttctt taagatttag ggcatcttca atcagcttat
    57841 aggcatttac ccttgatgta ccaaaggtca tttctgcaag gtcatttcct ttatccctgc
    57901 tttttccctc tacattccat tcacttgtaa tatttgaaaa tttaacctta atatcccatc
    57961 ttgcatatcc cggagttttt aaagtttcaa agatgaattt ttcaatatct ttaatcggta
    58021 tccaagtcgc accaagacgc acattgattt cacttgcttc taattccttt ggaagaactt
    58081 tggtaagctc tgctttttga tattccaaac gattcatttc atagcttatc agctcttttt
    58141 cttttccatt ctcaacaaag ccaagatgag gaagctctcg ttccgtttgt cttaactttg
    58201 caaggtagct gtctacaatg gcaatcttat ctctaatatt tccgcttagg tactcatcct
    58261 ttgttacata gccgtactta tatgaattac tgccgtttgc acaagcgaaa ggcaaatctc
    58321 catcttcaag gttaaaggat aatggtctat aaaagttttg ttcttctctg atgtttagat
    58381 aaatttctcc tctaagttct tctatcaaag ttggtctgtc tttacctgta aggctttcca
    58441 tatactcaaa atccacatag cctttttcag ataccgataa gacaagagct tcaagggaag
    58501 tgtccacatg gtctatgact ttggcttttg taatggttct ctttgagaaa atatccccct
    58561 ttgccttgac gttttcttct tcatcaagaa tttcaatgga agatacaaga gggaaattgc
    58621 tatcctcttt taaggctctg gtattgctta aattatttat aaagccatgc ttctttgaaa
    58681 agttgtcata gacttcatta agcttttctt gagctttctt tacctcatca tcggaatagt
    58741 cctctttctg cttgtagata acatctttaa gggcagtatt cagttcaaga tagtccttaa
    58801 tcttttcctt attcttatcc gttatctctt tcttgatgaa aagggagttt tctctgtaat
    58861 agacttcatc atcaataacg gtataggaaa agtttttgac atcatccgtt gcaggaattg
    58921 aagtgatttc atcatctaaa agctctattt cttcataagt tgatcctttg gatatttctt
    58981 cacttgcttt tgtcagaagc tcttttaagt cggcattttc tttcggcagg cacgcaagtg
    59041 tgtttccaaa tcttcctgaa acttcacgca ttgtgccgag tacctgctca ggatgatcta
    59101 caaaatattt gttataggta agaccatttt catcttcagc aaggtgaatc cagtcctcat
    59161 ctctttctct gatactgtcc cttttcttta ggaatataat atctgaggtt acttctgttc
    59221 cggctatgcc cttaaaggta tcatttggaa gtctgattgc ccctaaaaac tctgctcttg
    59281 ctgcaagata gcgtcttaca ctttcatcct ttttatccat tgttccactt gatgtgataa
    59341 aggcgataat accgccgttt ctgactttat caatggattt cgcaaagaaa taatcatgga
    59401 taaggaagtt atttttgtta tactccctgt catttacctt atattctcca aagggtatat
    59461 tgccgataac cgcatcaaag aagttattgg aaaaggaggt ttcttccagt cctttaatct
    59521 gcacttcact ttcagggtat agtagttttc caattcgacc gcttaccgag tcaagttcta
    59581 tgccataaaa cttggactta ttcatttcat cagggatatt gcctataaag tttccgatgc
    59641 ccattgatgg ttctaaaatg tttccctgtt taaatcccat atccgaaagc gtcttatata
    59701 ttccgtcaat tacggttttc ggtgtataaa agctcgttaa agtagattct cttgcagctt
    59761 cgtattctgc atgtgataag ttctcattta gaaaagccct tgcttctttc cactgacctt
    59821 ccttgctttc atcaaagact tcggaaagtc cgccccagcc tacatacctt gctaaaactt
    59881 cctgagctgt actgtcaagc tctctttgtc cgctctccac tctgttaagc atggaaattg
    59941 cttcaaggtt attatttaac ctttcgcttg gacttaactt ttcagggagc gtttcttctg
    60001 taattttaaa gttatgagct tccgctttcc ttatttgagt ttcctcagta gtctgctctg
    60061 gctgtttata tgtcaggttt tcaaataccc tctcaaggtc gctttccaga cgataaggaa
    60121 tgacatcgaa gcttgttatc atcccgccaa aatactcggt gttgtccttc accgttaccg
    60181 tatttaggtt ctttctcata tcatcaaagc gtgttatggt atggtttttg tccttgtatt
    60241 taacttcatc accgacaata aagttcggtc tttcaagact tattttattc agcaagtcct
    60301 cattatctgt aaagtctaca atcggaattt gatggtttcc acttcttacc ggatcaagcc
    60361 acaaatcata tcttcctgtg atttcatttt tagaaatttc tctgacttta tattcttcat
    60421 gattaaaata gacggtatcg cctgctttaa ctgcaaactc ttctaaaagg ctgtcctctt
    60481 tttcattcag ttctacttct tctctttctt tgaggtaatc aaataaggta gcttgaactg
    60541 tgccacgctt tgtagcttct tctgtttctt caggtgcttc aagctctact ttatcttcaa
    60601 agctaagttc tccattaaag acaaactgaa gctcctgctc atccatttgt tttataagct
    60661 ctatatcttt aagttctcta aaggtctttg gaaaatcctc taaaatgagc ctctgggcat
    60721 ttaattcttt cagttcctca aggttaaaat atccccattc aggctctatt ccaagaacaa
    60781 gtccaaaggc atcaccgctt tccctgtcat actccgtcat ataccaagtc caatttgaac
    60841 gaaaaggaat aatatatgct gcatgaacct gcttatccgc taaatctaca tcctcctgtg
    60901 cgtaaatctc tggcactctt tcaagaattt catcaggcat tagatttcca ggatcatttt
    60961 tagaataata ttgcggttct tttacttctt ctatctctgc cgtactttct gtttcctttt
    61021 cctcaaaata aagtttttta gaaagcagct catcaatatg ctttgcaaca cttgtccaag
    61081 taaggaacac atcattacaa tcattcttct gtaatttaaa accctttgca tcgtgccatt
    61141 catcacttcc cattgcacct gacacaacgt gagaatgtcc tccgattcca tattcatctt
    61201 ttaggaaatt ggctttttcc tgcaaagtat gattttcttt aaaaaacttg gtgattcgtt
    61261 cttttcctct atcaacgccg cttcctcttg aaaggctttc aaggacttca tcttctgtaa
    61321 taaagagctt taccttcgga agttctgtca gattggtact atattccttt cgttgcagct
    61381 caagttcttg caacttctga taaagactat ctaccttgtg ataatgatac cttaatacat
    61441 ttctgctttc tttgtatcct tctaaaaacc tgctatattc tttgattgtt tctttcagat
    61501 attcaggatt ttttaatgct tcagataatc ttttcgtttc ttgcggaaag ccaccacctc
    61561 tttcaaaaga gttgaaatat ccttgctcta ttccttcttc gcttaaatcg tgcgttagat
    61621 accataagga ttctgaaatt ctatcccttt catagtcctg tgcctctaaa agttctacat
    61681 ttgtagcaaa ctcacctctg tcaagaagtt catttatcct acttgctgca tcactccaac
    61741 ttaaaatttg tgtattatcc tctcttgccg atgttccata agctaaatga atacctttat
    61801 ccgaatacca ggaagatact tctctttcat caatgtaaaa tccgtttccg cctttaaagg
    61861 tatctttgag gtattctccc aattcttcta tgctcttgcc ttttgaaaac tcagcaataa
    61921 caggaagcct accgccatca tgatttcctc cgttaataag gacggtatct atatccttct
    61981 cagttagcgg aatagtaagg cttatctgtc cataagaatt ttcgggtaaa gaaaaagaag
    62041 ccttttcagc ttctattatc cctttatccg tattgtcttt taaatctcca ctacttcctt
    62101 gatggtcatt tctttgagag ctgaaatcat cgccccatac tgcggattgt tctcgtcctc
    62161 tatcttccaa gctgctatca actttggctt ctctgctctc ataaactcta ctgcctgttt
    62221 ctgaatatcc atcaggtgtc ctgtcagctt cttctccttg tatagatcca aaagcatctc
    62281 gaagtggctc tgctcctcgc tctgtgaaag gtaattcagc ctcatcactg cgtaggtcgg
    62341 attcggatac ttccttataa agtccgtctg ttcctccaag ctgtttagcg tattctccct
    62401 gattttttct attatctcgt ccgtactctc catttcggag aactcgctcg ttttcatttc
    62461 tttcctgatc atctcgtcga aatacatttt cttctacctc ctctaattct tctttaattt
    62521 tattatatcc cgcttctttt cctattaaaa cttctttttg aagctcaagc tctttgcttt
    62581 tttgaatggt ttcatcaata atctttccgc taatatccga tacactttca ccaaggctca
    62641 ttaaggatat gctgtcaaat ctttgaaaat tttctcttaa aagctcataa tccatcggat
    62701 aatctaactt aaatcttgaa gctaccgcat agcttaccga gtcccttaca aacttggtaa
    62761 atgatattct atcctcatcc gctactctaa gttcattcat taaggtatct attttttcat
    62821 caccgtagag tctgcttaaa gaaaagatgt tttcaagtgt gctttcactt tcctcatagc
    62881 cctcgctttt tatcatttcc tttaagacat cttgatgggc ttctttatca aatctccaaa
    62941 gattgacctc gttgacatcc ctgttttttg aaactgtctg gcttatatca aagatatagt
    63001 ccaccttttt atatgtgccg taatcctcta aaattggtat ccctttctgc cctcgcataa
    63061 ccgttcggtt aaagcgttcc ctccagtagt cgaacttggc acaggctgtc gcttcaggat
    63121 ttttatcata tatacttaat tgacttctaa aatcatacct ttgattgttt ccgacaactt
    63181 ttaggagctt tagatattct gcttcattat acaaaacatc ttgttttatt agctccaaaa
    63241 tgttatgaaa atcatttatt cgcattttta cctccttctt ttttcaaaca aaaaaggcgg
    63301 ttagatttta ctctaatcac cttcgctata taccaaatat tattactcta tttcaatttt
    63361 ttaattgatt cactttcaga tagtatcttc atttgttcaa tagctattgc atttaatttt
    63421 tccaatcttt cagattggct catgccttca tttataaata ccgcattaag attctcaaga
    63481 ttagaaaggc agacaagctg tgatatatcc gcataatctc taatattgcc ttttaaatcc
    63541 ggattttcat cacgccactc cttagctgtt attccaaata gagaaacatt aagaatatcc
    63601 gcttcacttg cataaataaa attgattttt tcttttgaaa gtttatccgg tacaagtttg
    63661 tttttaatgg catctgtgtg aattctataa ttgatttttg ccaaatttct cttaatatcc
    63721 catcctaact tcttttgttc ttcttccttt aggcgttcaa attccttgat taaatataat
    63781 ttaaagtatg gcgataccca agaagcaaac tcaaacgcta tatctttatg agcataagtt
    63841 ccaccatatc ttcctgctct cgcaacgata ccgatagaat tagttttttc cacccattgc
    63901 ttgaccgata atataaaacg gttaaatcct gcttcatttt taattccctc gaattcgggg
    63961 gaattaaaat tcgtgttata catttcttcc caaataccta aaaactctat tgtattcttg
    64021 tttctgagcc acttttcaat caaagcagaa ccgttctcaa tatttctaac catatccgtt
    64081 aaagaaatat aatctctatt gtctatggca ataatgctga tttctgaacc ttcaacattt
    64141 attttagaca tataatcacc tctcaatcat taaattgatt actttgcatt atagcatttt
    64201 tagagcattt tttccacgct gaaattagtg ctgtcttact tgcgatatgt caaaaccgct
    64261 tcttttatct cattttcaat cgcatctaaa aattctttct tagaggattt accctgagca
    64321 atatcagata attccatttc ccactttgct gtcgtttctg ccgacttaaa ggtatctgct
    64381 acaatcgtta caaggctgat tcctttatgc gttgcaatta gattcttctt atctctttcg
    64441 acaaatctct taaagattag attttcaata attcctgccc ttgttgccgg agtgccaaga
    64501 ccttttcttt ccacctctac acctttttct aaggcatcat ttcccgcaat ctccatagac
    64561 tttaagagcg tatcttcagt aaagtgtttc ggaggttggg taaatttttc tttaacctct
    64621 ttattttcaa cgctcaaaac atcaccaaca cttacatcgg gcaatacagc atcttcactc
    64681 ttttttgatt tgtattcttt aaggtatttg ctaaagcctt catccttaat taccttacct
    64741 gaacttgtaa attcaaaacc gtcaaatgaa gctacaatct ttgttgtatt ttcaataagc
    64801 ggatagccta cacttgcatg aaatttatcg gatataagga agtaaacttt tgcttcactt
    64861 aaaggtaatt cagaaacatc ttcttttact gaactgattg tcggtatgat tgcatgatgg
    64921 tccgtaacct ttttagagtt aaatactacc ttgatacgct ctgtatcaaa gtcattttta
    64981 cccaaaatgt tgttgactgt actcacaatc atatcctctg ttaaacatct gctgtctgtt
    65041 ctggggtaag taatcagttt cttttcatac aggctttgag tatagtcaag tgtctgcttg
    65101 gcactatatc caaaatattt attgcactcc ctttgaagcg tagttaggtc aaaaggtaaa
    65161 tcaggctttg taattttttc tttttgaata acatcagtaa tttcaatctt atcgcctact
    65221 aaacttataa gctgttcagc agcaacttca tcatcaattc tgtctgtgga gagtgtaaat
    65281 ccattcatag aaagctctac tgtgtaatat ttttctttct gataatttgc tatctcatca
    65341 tctcttttta caatcatggc aagggtaggt gtctgcactc tgccaacact gtaattttgc
    65401 tgatacagac aagagtagag cctactaata ttcattccga ctaaccaatc cgcaatagct
    65461 cttgcctgtg ccgattcaaa gagattatca tagtcttttc cgtctgttag gttatcaaaa
    65521 ccctctttaa tggcactatc ttccattgaa gaaatccaaa ggcgtttcat cttcttttta
    65581 caattcactt gattatatac aagtctaaaa atactttctc cctcacgccc tgcatcgcac
    65641 gcattgataa ccgtatcaac ctccttatca ttcatcagct ttttaaggat gttaaactgc
    65701 ttcttggttg cctttgctac ttcatacttg tagtcgctcg gaataatcgg taaatcagcc
    65761 atattccact tggcgtactt ttcatcataa gcatccggat ttgccatttg aattaggtgt
    65821 ccaacgcacc agctcaccct atatccgttt ccttcataat atccgtcttt ctttttattt
    65881 gctccaataa cctttgcaat ggagattgca acactcggct tttctgcaat aactaacttc
    65941 atctgtgttt tcctcctgtt ataaatcaaa atagggcgaa agatgttact ctcccgccct
    66001 aactttgcac ccaaaataat atgtttttag gtgcgtttat tcttcatctt ctacttcatc
    66061 tgcatcattt atttcttcct cgctttcaga ttcagaaaag aaatcatcat cttcctcctc
    66121 taaggcttca agttctttat cttctttctt tttcacaacc ttaaaatagt agcctgctcc
    66181 taatgcacca cctactacaa gaagcaaaat aatataggtt cctaaattac tcttttcgtc
    66241 cttcttctca ggctttactt cttccttaac aggttcttct tttactactt cctgctttgg
    66301 tgcttctttt ttctccacca tgttaagcaa atcatcttca gatacttccg taagaagcat
    66361 tacattctca ctatcttcat catgattgat gattaaatga aaagtcttac cgtttttcgt
    66421 ttgaaaggta ataaactgcc ttgcatctgc cgaatactga tccgtttctt tgttatcgct
    66481 gctatctcca tgatgaatcg gatactcctt atttgcatta tctttattct ccgtaacgga
    66541 tgctctcgcc tttgacggag atgaagctac tcccttgttg gtgtttacac tcttacttgc
    66601 agaccccatt gatgaatcct gactgttatt cgcaggagct tttgccgtca acttattggg
    66661 atagcgaact tccttttctt tctcctttac ttccgttttg cctttaccgg tatcctttgt
    66721 agtattacct gagcttaccg aatccgatga gcctttaccg gtactactta cagaagtctg
    66781 tggtgtttga ggagaaatac ctgaacttgt cttaattccg gaaataggac taatcggtgt
    66841 aactgattgt gatgttacag gagctttatt tgtttcagtt gcctttttct caagctcttt
    66901 caccttttcc gtcagcttat ctatttcctt tttcatatct tctgataagt ccttatttcc
    66961 cttatctttc ttcatttttt ctttcaggct atcaatttca tcttcaaggt ctttaatttt
    67021 attcttttgc ttatcactta atttgtcttt gtccttaagt tcgcaattta acttatcaag
    67081 tttatcctga agctcttttg cctctttttc tatttttgaa atatcgtctt tagaaagctc
    67141 tgtctgcgtt cccttatctt ctgtctgagt gcattcatcc tgctttggct tttcttcttc
    67201 cgtctgcgtt tccttatcct taacctccat ctttgctacc ttacggataa tctcatcttt
    67261 tccatctccc tttacctcat aaaacagaaa ttcatcaatg aatttcatat catctgggag
    67321 cattggaaga tctccgctat caataagttg tcctttctca gcctttatct tttcttcctt
    67381 aaagaccttt tcatcttcaa agatatacct tacatttact tcaacttccg tttgaacagc
    67441 ttcgtttttt gttggagctt cagatttttg ctcctgtgca taaacaaccg tccaaagacc
    67501 taaaatacaa ctaatactta caattaccgc aagtgctacc gtccaaaact tattattctt
    67561 tttcaaactg gttttcattt gttttctcct ttttcatttc tgctttttgt ctgtttacct
    67621 ttgctatcaa atcgctgatt gtgatgttgt tctttctgca aatggcaatg atttcttcat
    67681 tttcaagctc ttcttcacga atgaataaag gctccaattc ttcatcaatc agagcctttt
    67741 tatcctttaa cttctttatt ctgtttttta ctgttgtaag ttcctttttc aaattgttac
    67801 ctcctatttc tttacatttg gcggaaaacc gaatcctacg ggatggtgct tacaaaatgt
    67861 tgctatccaa tcatctaagg tagttactct tattcgaccg atgttatcaa tcacttttcc
    67921 atctccaatg taaataccta catgaccata ggtaagccct gcactgcttc cgctactgct
    67981 gctttcaact gccacaagca ttcccacttt tagctttgac ctgtctgatg taaaggtata
    68041 gtttcggtac atatcacagg cattcccgcc tatatatcca agtcctgcat tttgatagac
    68101 ctgtgatacc cacatggcac accagcctgc acccggagat ggcgtaatgt atgcagcatt
    68161 aacaatcttc ttttgtactt ccgtagatgc ctcatactct tttccaccgc cgatacctcc
    68221 atttgcactg ataaggtcag aattaccaaa ggcttctctc atattgcctt gtgcaaggaa
    68281 caaggcttca tagtgcttta gattatcggg atagtttgca aagacctttc ggataatact
    68341 gtccatctct tttttatgaa gcgttacgat gagtttttta tactcataag gttcttcgtg
    68401 gctttcggta tattcattgc catcttcatc ggtataggtt tccgtaaccg tcctgtatct
    68461 gatttcaatt tcttccctat actcaaggtc atacatggac tcaaataatt cttttaatat
    68521 ggattctact tccgatacac tctttacctc tccgcacctt gatgtaatgt aggataaaag
    68581 ctcatggaca ttatgaccga tgtattctgt attatttaag atatattcat catatccagg
    68641 ataattttct ttcacatagt caacttcact ttgaagctca ccctccatat ctgaaaattt
    68701 ctgattgatt tcacttagga catttggctt tgataaatag cttgttgtaa gcacagagct
    68761 tgtagagttc ataaagcctg tcattcccgt tcctgcaaag ttaatcacaa aagtccctaa
    68821 gataatgata cctatgaaaa taagcattag tccttttgct tttcggataa tcatatcctt
    68881 tgagcttttc agtgttccga taagtccctc tttaattcga tctctaagcc ttgacttatt
    68941 ctcacgagaa attgctgcct ttacctgatt tttcttttga aatcttttat atgcacttgc
    69001 tcttttatac tcatccgtct ttttcagttc ctttttggca tcacgaaatt ccaactttga
    69061 cttacgcttt ctgattttat agtccttatt tgtaaggtca tagcctcttt tagctctttt
    69121 cttatcagag tacttcttta tgccatgaat gagcttggag cttgtatctg ctgtcttttc
    69181 tcctgcttcc actccttgat tttcatcact tccatgagac aagtaatctc ttacagtttc
    69241 acttccttta gcaagtcctg aaagggcaga tacctttacc atgtcttttt ttagcttttt
    69301 cttttggtct tttgataggc tgctataaac ttttccgctg acagcatctt ttcccgcctt
    69361 tttatcatca gccttatttc cctttggtgc atcgtccttt ttccttgtat aaaggctttc
    69421 agaatagttc ttcctcttgt acctgctttt ttgagtctta tgatttttaa aggaattttc
    69481 taatgatttt tctttatggg aaagattatc ctccacatca taggtcgatt caaaatagtt
    69541 gctgtctcta aagtcattat cgtatctgtc tataatcccg tcattatcaa ggtcttttcc
    69601 taaaggatca tagatttttc catccttaac ctccgtaata taatctgatc ttcccgtttc
    69661 aattgcggaa tttacgtctc ccttatctga agttctatat ttttcgtttc tcttggatgt
    69721 tccataagac ttttcattat cagcacttac cttacttgtt ttttcatgca ctttatcctg
    69781 aaaccgttct ttctcatgaa cgattttacc tctgtaatca tcgttatgtt ttagcttact
    69841 ttcttcaggt atcgtatctg ttttactatg aaacatctct ctttcaaggc ttgccttatg
    69901 cctttcctta aaatcctttt tcagcttctt tcccataggc tacctcactt cttccggctt
    69961 ggtagtcatc ttctgatata aaattgtatc tttcggaaac ttatcaatga aaggcacaat
    70021 ggtatttcca aagaataaga gtccctcacc ttcatttgaa ttagtaacat atctgagctg
    70081 tggaagtgag attttaagtt ttcttgcaag tatctcccta tctcctgatg cttgattaag
    70141 cattaagaca aagtctgtat tgtcaaagat attttctatc tccttactca taagtaggtc
    70201 tttgacattc tgcgtaatac ctgttggaat acctccccat ttacgaaatc ttttccaaat
    70261 ctctacggaa taggatgctg tctgctcatc ttttaaaagc aaatggaact cgtcgatata
    70321 gtaccttgta gccttgtttc ctctgttttg tgacacctta ttccacacct gatcctgaat
    70381 aacaagcata ccgattttct ttaattgact tccaagctcc ttaatatcaa aacaaaggag
    70441 cttcttattt aaatccacat ttgacctgtg attaaagaca ttgagagacc ccgatacata
    70501 gatttccatc tctgttgcca gcttcttacc gaccttttct tcctgccctt ttaacatatc
    70561 gtataggtct tgaagtatcg gcatattgtc aggagtagga tgttcaaaat acttttcata
    70621 gattttagga aggcacctat ctataacgga cttttcttct gctgtaagac cactaccgcc
    70681 tactacaagc tcaagcatac tcatgataaa gtttgccttg tctttcagcg gtgcatcccc
    70741 atcaccgtag ttcatgttta tatcaagagg attcaggtaa tccttcgact tactgctgac
    70801 cttaatgact tctcccttaa actgccttac gaggtttcca tactctcctt ccggatcgca
    70861 gataatcaca tcatcatctg ttactaaaat cgcatttgcc atttctcttt tggcactaaa
    70921 ggacttaccg ctgcccggag ttccgaggat tagaccgttt gggttcttta atttctttct
    70981 atctgccata atcaggttat ggcttagggc atttagtccg tagtaaagac tattacttga
    71041 attgataaaa agctcctctg tggtaaatgg cataaatact gccgttgatg agcttgtcaa
    71101 tcctctatct atttcaatct tatttacacc aagaggcagc acgctcacta aaccttgttc
    71161 ctgagaatgg tcaagtcttt tcagcttaca gttatgctta tttgcaatgg agcttatttg
    71221 agcaattgtg ttatcgagct tttgcactgt ccttgcaaag ttcataaaga cgatacttac
    71281 cacaaacatt cgctcatctc ttgtctgcaa gtcttttaag aggctcttta catcctcacc
    71341 ataggtaatt aagtccgatg gaagaatgtc catatcataa ccgcttctta ccgccttctt
    71401 attttcctca attttcatct tatcaatatc agtgtttttt cgttttacca tcttaatggc
    71461 ttccgattgg tcgattgccc taatatgaaa ggaaatattg atgttatcgt caatatccaa
    71521 aaactcggat aacatcctat ctgaaagctc actggcaagg atttgaaaat gacttgttgc
    71581 tccgatgaat ttgccgaact taaagtatct actcggtgta aagttaaact catcaggcac
    71641 aatatatgtc tttgtgcttt cccttttctt taggtctttg taggaaaatt taaatgtttt
    71701 atttggattt aaaacatcat gaagtatctt tagcctttct tctccgttta ggctttctgc
    71761 tcttactccc atacttttaa gactcgataa tatatctatc tccagtcttt caagttttga
    71821 tgttgcctgt tctaaattat ccgcttccac tgtaaaggtt acatactttg attttttcaa
    71881 tccgttattt ccctttacaa tctggctttt aagcatctct ctaaattcaa agcgtatatc
    71941 gtcgaaaccg tcctttttat ccggtatctg aattgccgac ttcatttctt cgtttcgtcc
    72001 gagctgattg atatatgaaa actcaatgct gatacttgga tcaaaagagt ttaggaagtt
    72061 tgcaaattga ttaaaaatca agtccctatc ttcatctaag gcaagctgat agttaatgtc
    72121 ctgaaaggct atacttttac tgaagtgctt ttcatcaagc tggcatattc cgctttttaa
    72181 aagccttaga tagggaatgg tatcttctac cgtatatctt ttcggttctt tcttaaagat
    72241 aaggtcaagg attcctccct tatctttttt tgacttgcaa ttacttttct ttaagtcccg
    72301 cttttgactt ctcaatgcct tttcgttttg catgagtttt atttgctgaa tttttctttt
    72361 cttgttcaag gtaaacctcc tttctcactc tcttttgcgg ttgataaaac ttatgaagat
    72421 aaatgtactt aaagtatttc tcaaatgtca gtccgtcttt ttcaaatagt gtgatgaaaa
    72481 agataggaag cgtggatacg ataaggaata tgacagctat gtcatttggc acaaacttcc
    72541 tcataaataa atagactggt attccaacca gtcctgcaag tgtgaagcct atgagctgcc
    72601 ttttcgttag gttaaaagca acctttgtct ttaccctatt taagtcttta gggattggta
    72661 catatgccat atcttacctc ccatcttctt taccctttga cagctcctca aagtgttcat
    72721 atacagagcc gatttcttcc tgaatagtcg caagctgttc gtctgtgttc ttgttatatc
    72781 tttgctgtat taggtaaaaa tcgttatggc agcgaccaat gtcctctgtt ttttcttcca
    72841 attcttccac cttattatga agcctgatcc tatcaattat cgccataata cctgctccaa
    72901 ttactactat aaatactgtt tttcttttgt tcatattacc cttcctttct tttagtgtgc
    72961 atttaatacg cttttggcca gtgttccgct ctttaacatc attaacccta gcaaaaccgc
    73021 atatccaagt atcgtaaagg tacttgtgtg tatatctgtt atctgtattg tcttaactaa
    73081 tactgcgtat attccaagac aaaccattaa aaagagtcct tgtaaaccta tggcaaacaa
    73141 tcctttgata tagtttgttc caatctgtcc ccactctttg tttcccattg tggcaaatgg
    73201 aatggctgaa atggatgagt aaacataaat ctcaaacatt cttccgtaaa ccacaagcat
    73261 aatcacaatt gaaatgacct gtattgccac ctttataagc gaggtttcaa agagtatcat
    73321 gacaagctct ccaagacctt tatcctttaa tccatctacc atttttacta tctgatctcc
    73381 ggagataacg gcagaagtat tgattacccc tgccgcttta tttaccatgt gctgtgccac
    73441 atcaaagacc gccattgaaa actcaaatgc atgtgatact aaccatacag caatccacat
    73501 cttgatgatg tacttgaaaa attcaaaagt atctgtatcg tgcatattgt tcttttgcat
    73561 taccatattg ataagctcga tacaaaggac tgctgtgatg attagccctg ctatgggaat
    73621 aatgacggaa tcgttaatgc ttttaataaa ggcaaataca tctccgttcc accccatagg
    73681 agtttttcct acatctgttg caactgcacc aactttatcg ttgatgtcaa gaaacatgga
    73741 ctctaagttt gcttgaatac cgcccagtag aagctcttta aagaattctt ctatcttgtc
    73801 gaatattcca aacatctaag ctctcctttt cttattactt gagtacattt gcaagaagcg
    73861 gaatcagctt aagtccgata aggacaatgc ctcctcccgc cataagctgc ttgatgccct
    73921 gagatttcgc tcccggatta tcattaccat atccttccat aaggttaata actccccatg
    73981 ctccaagtcc agcacctact gccataacta aaatctttaa tacatttact gcctgtgcga
    74041 aaaattccat aatttattcc tcctcatttt cttctttctt ctcaatcttg ttatatgact
    74101 tcactacaaa gtttttgtaa gtctttccct ctttttcacg cttcttaaag tagccgaata
    74161 catgaatcaa atcgcctttt tcaaagtcct ctgctttctc tgctttttct ccgtaggctg
    74221 cacaattgat gtactccttg ccctttccat atttttttac aagcgtaaag tttacaactt
    74281 ctacttcttc accctctttt tcaaaacttg agaaagtagg ttctgccact aagttggcgt
    74341 tgatgttaat catttcttgt ttcatctttt taaatttctc cttttcattt caataaaaaa
    74401 aacgactgga gtttttcttt tccaatcgct gatactctta ctatttagtt ttcgtttaag
    74461 tgggatttct gatccttatc atcttgcctc ctgattttga ataaaaaaac agcaaatctt
    74521 tttaagactt actgcattct tgtaataacc gtctctctat ttaattttgc ttttcctttt
    74581 cgcttcatat agctttctat gtcaaacaaa ttcttcttgt cataatcctc aagcagctta
    74641 taattcttgt gctttgtaat atcgtattta tctgaaagaa aaggtctgac acctctaagc
    74701 tgaaatatac attttccacc gtccattaca gtaatctcat cttgactcat cagttctttg
    74761 ccacaatgtc aagtgatgaa ttaaaaaaag ctatcaaaga aatccttctt cgatagcagc
    74821 gtattcaaca tctattcaca tttcctgcct tgcgttcttc gagctgatga aatataataa
    74881 gaaatgttgt cggaggtgcg aatatggact acatgacgct caaagaggca agcgaaaaat
    74941 ggggcgtttc gtcccgacag ataaattatt actgcaccga tggacgcatc cccggtgctg
    75001 tcaaaatggc cggtgtctgg ctgatcccca aggaggcaga gaagccaaag gacagacggt
    75061 ataacgaaag caggtgatac agtgctgcat atagcaattt gtgatgatga aaaagacttt
    75121 gttcagtatt tgaccgattt actgaaccaa tacagcaagg aaacaggacg ggacataaag
    75181 attaccccgt actatgacgg tatggagctg attgaaaaat acgatccaac catagacctg
    75241 attttccttg atattcaaat gaaggtggtg gacggacttc atgctgccga gcgtatccgg
    75301 caaatggacg aaaccgtggg cattattttt ctcactactc ttacacagta tgggcttgag
    75361 ggatataaat accatgcgac gaactacatc attaagccca tgaaatatgc ccggctcaaa
    75421 tcagaaatgg acaaattctt ggagcgcagc cagaaagaag ataccccctc tctggtgatt
    75481 accaacgata ccggcaaata taaggtgccg ctaaaatcaa ttcgatatgt tgaaacatat
    75541 aaccgcaatc tgatgttcca taccgagcag gaaaatatta tctgctataa gagcatgaaa
    75601 gaagtggaac gggagctttg cgacaaagac tttgtgcgct gccataccag ctacattgtc
    75661 aatctgttct atgtgaaagg catcaagaag ctggacattg aattgattac aggcgagatc
    75721 attcccatca gccagccgaa acggaaagaa tttatggaac ggctgacgga ctattggggg
    75781 gatatgctgt aatgtggtta tatcaagtgc tcgacataac agcaacgctg acagaatctt
    75841 tgggactgta tttattcagt atttgttttt gcaaagaacc acggtatcgt gcttctgtaa
    75901 atagatggct tataacaggt ataagttttt tgtgtgcgta tacattgaca tggttttctg
    75961 aacttggcgc actcaaagcg ccttttcttc ttacgattta tcttgtcctt ttgaaagttt
    76021 gttatagaga ttctgtctat caatgtgctg ttgctgaaga actgaattat attgcaactt
    76081 gttctcgata ttcgcaaggt agcgcgggga aatatataac tcgtcgctta cctttttgcg
    76141 gctctcgccg tattcatttc tcgcggcttt tatagctgcc ccgaaagcct taaagtcgta
    76201 caatggtacg ggtctttttg ccattttcat tcaccctgtt acattttaca gttcaccttt
    76261 ctttttggat atgtccacac aattcatatc attaggttaa atacttcctg ttgtgtattg
    76321 acagtagact gattttctga taaaataaaa tttatgtaaa aggaggcggc gtttatgttg
    76381 catagcatgc gtattagata agcattgaaa aaaaggattt tcccattttc aacatgggct
    76441 tttttgtcat gcttattttg cggatgctat acaaaaaact aacgacgtat agatatagta
    76501 tagacatagt gcaagctatg ccttagtttt gttgtactgc tctgtgcatt ttttgggtag
    76561 ggaaaccacc ggctgtgccg gtggaggtac cccgtaaaaa agctttagct tcaagcatcg
    76621 agcgaagcga gctgctaaca gcaaattatc agtgaagaaa gacttgcatt agaacagcgg
    76681 ctgcccgttt acgggctgcg gggcaaatga tgcgggtgaa ataaaattca gtgcgtcttg
    76741 agacgcatgc cggtaatagg cccttatagg gccaactcaa gccaccggct tagccggtgg
    76801 ttatgacttg tgtaaaaagg acgagtgaaa tataatgctt aaaaaatatt ggataaaatg
    76861 tccgatttgt aacggaaaga cgagagttca agtatttcat aatactgtat taaaagattt
    76921 tcctcttttc tgccctaaat gcaaattgac gcatatcatt gatgtagaaa aattagagat
    76981 tgtaatcaaa aatacagaaa aacaaacttt tattatttag aagaaaggat ataaaaatga
    77041 aacgtttacc taaatatacg cctgcggaag tacggaatga tccatacgga tttacttaca
    77101 aagaaatgtc ggaagttatt ggcgagaatg aagcaaaagc cttatatgaa gaattatata
    77161 agcaattacc acgcaaaaaa aatctatcaa tgttggtaaa aaatatttgc aaaagcagtg
    77221 atactgaaaa gtatgtttac gaactgaaag acaacaaata cattgaaacg gtttttatca
    77281 agcggcgaga tggtggaact gtttgcgtga gcacacaagt cggttgtcct gttggttgta
    77341 ttttttgtga gtccgggcga aatggctttg ttcgtaatct aacatcgtca gaaatcgtac
    77401 aacagattat attgttgcgt cgaaaagtaa accgtatcgt ttttatgggt atgggagagc
    77461 ctttattcaa ttatgacaac ttgataaaag caatccatat tctccgagat agatatgggc
    77521 tcaactttcc aaccgacggc attaccatat caacagttgg tccggtcgat caattaaaaa
    77581 aattgcgcga ggaacatctt aaaattcagt tgacaatatc tttacacgca gcaacacaat
    77641 ctgcaagaaa tcgtattatt cctcacatgc gcatatatgc tattgaagat gttgttaagc
    77701 aagccttatc ctattctgaa aggcataatc gcaaaattgt ctttgcgtat ttgcttttac
    77761 cgggtataaa tgaccggccc tcagatgtaa gacaacttgc aaaatggttt cggggcaaaa
    77821 aagttatgat taacgtgtta caatacaacc caacaagcaa ttcaagaatt aaagcaccac
    77881 agaaacggga aatagttgca ttcaaacatc aattagagca agcaggactt gaagttacta
    77941 tgagagtttc tcatggcaga gagattaacg cggcttgtgg acagttagct aacacatata
    78001 ataaattcaa aaaaaaatga ttaaaagtgc cagacgcata gacgcagagc cgataacgca
    78061 ttaggtcaaa aaacctatgt gttatcggct tttttattta atattgcgca aaagccgctg
    78121 ttccctatta tagaatggat tgcgggtagt gtattaaagt cgcccttttt taaggatacg
    78181 gcggtatcgg ggaggtatcg ccgtgtccat ttttatttac tgtaacccgc ctaatgcttt
    78241 gcggtcaaaa aaagctatgc tccgcaagcg ggatattccg gctatgaatg tgaactgtca
    78301 atacatttag ctactgctta catttccttt gcgcccgtcc gcgtcttgcg gacgggcgca
    78361 ttttgctttt ttcaactttt ttctgaaaag cgcactcaag agccatctcc cgaacgggta
    78421 cggagcgaaa ggggcagaga ggacaagccc ttaactcccg tcctctactc cacgcgggaa
    78481 ggaggtgaac tctatggagc tatcttcttc cgacaaggaa agaatacaac atcagtacga
    78541 cgcattagca aagaaaactt tggtcggcga agcgaaaagc caccgccgca ctcttgcgaa
    78601 acgcgcagca cgcgaagtta ctttttcgga tttgagcgaa agcgaactcg cgcagctttt
    78661 cacaacggac gaatacgaaa gcgattattt ccgttttcaa gtgtccggct ttgatgtact
    78721 cgtcaaaaat gaactgcttg ccgaagccct taacgctttg cccgaaagga aacgcgacat
    78781 tatccttttg tcctacttct tggatatgag cgacgcggaa attggcgaac tgctgaatgt
    78841 tgtacgcacg acggttttcc ggcacaggaa atccgcgctt gcgaaaatca aacagtattt
    78901 ggagggaaaa gcagatgatg aataccgtta ggaagtctga aaatctgttg ccgttccctg
    78961 tcatttccgc agcggcaaac ggcgacacaa ccgccatgtg cgcgatcttg aagcactacg
    79021 agggttacat agcgaaactt tgtacccgca cgctgaaaga cgacgcgggc aatacctatt
    79081 cctatgtgga cgaggaaatg cgtaacaggc tgcaagtgcg ccttattacc cgcacccttg
    79141 cttttcatgt aggataatct tttagcccat gcggggagcg tgtccccttt ccacgcttcc
    79201 cgttatgggc tatttgtcgt tccgcaaaag catatccgct gttgatgtgc ttttgcaggc
    79261 cgacaaagcc tattgttctt tgacaaagaa agcggccttt ggtgcgcagc ataacaggca
    79321 aacgggtaca ttccgtctgt accgagccag tcggcgggta cgccatgaca gcttttcccc
    79381 ataggggaaa agccgagcga gaactaccgc gccgtaaaac aggtttagca gcttgtgggc
    79441 gacgacatac aaggcggcac aatgatactc ccgcgttgaa caccctcaaa gtattgcgcg
    79501 gcgcacccat aagcatgggc cggggtgaaa ctcccgtgag gttgcagcta acaaccgccc
    79561 gtttttgcct tttgacgaat atagtttatc catacaggaa aaggaggttt ttctaatgga
    79621 taaaaaacag acaattacaa ccgaacgcaa aatagggaaa atcacctatc ttgttcaagc
    79681 gttgccgagt gaaaaggcaa ccgatacaat ccataaaaag attgagaaac tcattgtaaa
    79741 ggatttgcag aaaaagcccg gaaatccggg atttttagcg tccgagtagt gcattaggcg
    79801 gcgggatatg gtataatgat agcaacacat tatacctgtt tattcggctg tcggaaagga
    79861 ggactaatgt tacagtcgaa taaaatcacc gccctttact gccgtttaag tcaagaggat
    79921 atgcaagccg gagaaagcgg aagcatacag caccaaaaaa tgatacttca acgctatgcg
    79981 gacgaacacc attttttgaa cacaaagttt tttgtggacg acggattttc cggcgtgagt
    80041 tttgagcgcg aggggctgca agcgatgttg caggaagtgg aagccggacg agtggcgacg
    80101 gtcattacca aagacctttc ccgtcttggc agaaactatc tgaaaacggg cgaactcata
    80161 gagattgtat ttcccgaaaa cggagtacgc tatatcgcga tcaacgacgg agttgacaca
    80221 gcgcgggagg ataacgagtt tacccccttg cggaactggt ttaacgagtt ttacgcccgc
    80281 gacacaagca agaaaatccg cgcagttaaa caggcacagg cgcaaaaagg cgagcgcgtc
    80341 aacggggaat atccatacgg ctatatccca gacccgaaca accgccacca ccttataccc
    80401 gacccggaaa ccgcgccgat tgtcaaacag gttttcgcta tgtttgttag cggcgtgcgt
    80461 atgtgcgaaa tccaaaaatg gcttgcggaa aacaaagtct tgacgattgg agcgttgcgc
    80521 tatcagcgta caggacaggc gcggtatcag cgggcaatga tcgcccccta tacttggccg
    80581 gacaaaacgc tctatgacat attagcaagg caggaatatt tagggcatac cataaccgcg
    80641 aaaactcaca aggtatccta caagtcgaaa aagacccgga agaacgaaga agaacaacgc
    80701 tatttcttcc caaacaccca tgagccgctt gttgacgagg aaacctttga acttgcgcaa
    80761 aagcggattg ctacccgcca ccgcccgaca aaagcagcgg agattgatat tttttccggc
    80821 ttgctgtttt gcgctggttg cagacataag atgtattacc aacagggcgt aaatatcgag
    80881 ccgcgcaagt tttcctattc ttgcggcgca tggcgcaaca gggcaaggac aggcagcgag
    80941 tgtacctctc attatatccg caaaaacgta cttcttgatt tagtgctgga agatatgcgg
    81001 cgggttttgc ggtatgttaa ggaacacgaa caggacttta tctgtaaagc taccgagtac
    81061 ggcgacatgg aagcgagaaa ggcattagcg cagcagcaaa aggaactttt caaagcacag
    81121 gcgcgtatga ccgaacttga cacgcttttc cgcaagctgt atgaggacaa cgcattaggc
    81181 agactgacag atgaacggtt tgtgtttcta acttccggct atgtggacga aaagaaatcc
    81241 cttgccgcaa ggatagacga gttacaacag cagatcgcaa ccgttaccga gcgaaaaagg
    81301 gatatatcaa ggtttattca gattgtcggg aaatacagcg acatacagga attgacctat
    81361 gaaaacgtcc atgagtttat cgaccgtatt ttgatacatg aattagaccg ggaaaccaac
    81421 acccggaaaa tcgaaatcca ttatagcttt gtcggacagg ttgataccga gcaggagccg
    81481 acgcaagttg tcaaccatga ccgccgcaac atggtagatg taaaaagtat cgctatctaa
    81541 ccccagcaaa aaaggggcct gaaatgaaag agtacacgct aattatcaag ggagaaatgg
    81601 attttatcat cttatctccg caggtgcttt cttccctgat tactcaaatc cataacagcc
    81661 cggagcgaaa agttgtggta agtattgaga gcatcatgcc accaaagttt accgactatc
    81721 tgcttcgggt aatcaatagc aaccgcttta gcaatgaacg gttccgctat cgctacattt
    81781 tagaaaatcc tgttacaaag aaagggatgt atgagatttt acggcaacag ctttcccgca
    81841 ccaatacgga gcgatttcct tgttttcaga ccatacaatt gaccgacact ttccagggta
    81901 atgtggagct ggacatggag tgcaacgatc tgttcttttg ggcttgcaaa gatacagcag
    81961 caaagtttgt ttacacgttc ccggatggac gggaggaaac actggtgatt gaatactgaa
    82021 tgagaaaagc cccatccctc aatggttgag agatggggca aactatttac gctgcaatct
    82081 ccgggatttc cccgacaaag ttataaacaa ttctgacttc ctgcaccttc tgaccgtcca
    82141 ccttcttaac ctcgccgatc aggattttgc tgataagccg gttcagtacg gactcgtcca
    82201 gttccgcaat ggcggcatag cgccggattt ccttgataaa ggttcggact tcgctttcct
    82261 gtgcgtccgc ccggctctgc atcaccgcca gatcgtgcag gcgtttctga ttggcttcct
    82321 gctcctgttc cagcgccgcc gtcagcttca taaaccgctg ctcggtgagg acgcctttgg
    82381 ccttatcggt gtacaggctc aaaaacatcc cgtcaatttc ctgattccgg tcttccagcc
    82441 gtttccgttc cttctctgtc tgggaagcgt ccaccagata ccggcgctcc atccggctgc
    82501 tgagccgctg gtagaacgca tcggcgtcct tcatggcctg cgccgccaat tcctgtatat
    82561 ccttcagcac cagattgtac aaatcccttg cctcaatctt gtggctggta caggcgttct
    82621 tgcccagccg gttgtaagtc tggcagatat agtatgccct gtcaatcggc tcccgcattt
    82681 cgccggtgaa gcggttcttc ccggttctgc cgaccttttc ataccgcacc tgcatggact
    82741 tcccgcaggt ggcgcagtag acaagcccgt ggaacaggtt atagaagggg caggcgttgc
    82801 ctttcataat ggttggcctg cggtcaatga tgtcctgtac ctgttcccat tcctccggcg
    82861 tcacaatcgc ttcgtggcag ccctcgatga cctcccaatc ctcacggggg ataatgtcat
    82921 aagtgttgga gcggatgcct ttctggtgtg tccggcagac aagatgtgcg cctttataaa
    82981 agggatttct caggatatgg ctgatccttg cgctccccca tgaatagtag ttcacgtcac
    83041 attctgtatt gctttttact ctggtgatgg ggattttatc atccatgagc tgctttgcga
    83101 tccgcataca gccccagccg tccagtgcca tatcatagat ttttcggatc accggcgcag
    83161 tctccgggtc aaggatcaga tgccctttgt cctccgggtc acgcatcagg ccaagaggcg
    83221 gctgcccgcc gcagaacttt ccctgccggg aacgggtcat gcgtcccgcc agcacctttt
    83281 tggaaatatc ccggctgtac atatcgttca ggatattctt aaagggcgtg atgtccattt
    83341 cctgacgggt caggctgtcc acaccgtccg tgacggcgat atagcgtaca ttgtgtttgg
    83401 ggaaaaagat ttcgatatag ctgccagctt cgatataatt cctaccgagc ctcgataggt
    83461 ctttcgtgat gacgcagccg attttccccg cctcaatgtc agcgatcatg cgctggaacg
    83521 aggggcggtt gaaattgcga cccgtatagc cgtcatccac ataatactca tactggaaca
    83581 tcccatgctt ttctgcgaag tcccggagca tgagtttctg gttgctgatg ctcatgctct
    83641 cattgtcgcc gccgtcatcc agagaaatac ggcagtagag agcggtgatt ttttcataga
    83701 cttgtttttt cctgctcata gcgttctcct tctatgaaca gggacacgat accattatag
    83761 taccatgtcc ccgtccctga atcaaccgtt tttacgcagc tttttctgcc atttcccgct
    83821 gatgacgcca ttcctcgaag tgttcgcagg tctggcgctc aatgagctgc tcaaaggctt
    83881 cccgcatgga cttctccccg gagaactccc gcaccaccac aaaacggact ttattcttct
    83941 gatttttgct tttttccata ggctacctcc atagagagac aggccgaacg gcagcaccgg
    84001 caacgaagtc cggcaacgaa cctctaaaaa cctgtaaact accgtctggc ctgcaaatct
    84061 tactttgtga attttcttga aaaatctcgt tgctttcgtt gccggagata atgataaata
    84121 ttaaaatatc ccttatttac tggctttttc cgtatccaga cagggaaatc cccggcaacg
    84181 aacccggcaa ccaagtggca accatcccgg caacagaccg ccattttcag gcgatccact
    84241 ccttcggaag ctccaactgg cggcattctt cctcgctcag ttccacaaat ccatcttcgt
    84301 tgccgggcag ttcgttgccg gaaacgtccc gttcccagcc cttctgcctg ccgtatccgg
    84361 cgaacatccg gggattggag aatggcttcc agcccgtcac cactgtattc atgatctcgt
    84421 tgatattgtg aagctgccac cgcttcggct cgtcataggt gtggcccaat gcctccttaa
    84481 aaagctgttt ggaacagacc atgctgccgg tataatgttc cagaaagccc tgtatttgac
    84541 cggcctccgt gtcctccggc atgaaatcct tctgcacctc cacaagctgc cgctggatgg
    84601 acttgctgaa tttcatggaa tacttcccgc tgcggtagat ggtcatggcc tccgcccaga
    84661 cctgcaacag gtaggctctg gaagcgtcct cgtcctccaa aatgtgaacc tccgctttct
    84721 ccgggtaaat catgatggga aggaaacgcc ggttcccggc ccggtcaagg ggcaggaagt
    84781 ccagcgtgtt ggatgaaccg ccgaacacgc actgccgcag ccggtctttg ggctgggcct
    84841 catagggtgt gcggtaggtt tccttctggc gactgatgaa cgagcggatt tcctctatgc
    84901 ttttggcgct gctggtggcc agcatctctg acatctcaat gatccagtgg ccttgcagct
    84961 tcaaaaatac ccggtcatcg tccagctttt tcaggtcatc ggagaaccac tcgtcccgga
    85021 tcgccagcag gcggaagaag ctggacttgc cagccccctg tccgcccacc agacagagca
    85081 tttcctcgta tttggagccg ggagaaaaca cccgccggat ggctcccagc aggaagtgtt
    85141 ttaacatttc ctctacataa tcgctgactt ctgcacctaa gaagtgatgg agacaggagc
    85201 ggatgcgggg cgtcccgtcc cacacaaggc cgttcagcac gtcctgtatg ggatggtagc
    85261 agttctcatt cgccacgatg gagagcgccg ccgtcatttt cttctcgctg gtcaggccgt
    85321 agttctgctc aaaatagaga agcagatact tcacatccgt atccgtcagg gcgctggtgt
    85381 tcctgcgcca gcccaaatcc cgcacgatgt ccacccggtc agtcaggagg ttcagccgga
    85441 tggcgtcccg caggagaggg tcatgggaga acaccgtccg gcagttgccg atggtgttgg
    85501 cgggctggcc cttctccgtg acagaaaggc cttcccgcac ctcgtcaacg ctctgctccg
    85561 gcgctaaagc ttcggctgcg ctcatgacgg cctgccgggt ggctggcggt aaactctgat
    85621 attcgctgct caatcttcct cacctctttt ccatactcag cgaccacgca ggcccgttcc
    85681 tccatactgc cggacagcag aatatccagc agatactccg tgtacggctt tttttgcagg
    85741 gcctccacaa acagcgggtt ccatgcttcc tccggcgtct gcggggcata ttccttctcc
    85801 cagcgttcca gcagatgcag ataatcgcac aacacccgga aacatttctg ttccgcctgc
    85861 cggtagcgca gttcctcgct gatttttcgc ttgcccggct tcctgcgggg cgggtcatgg
    85921 cctttagcgt caaagccgac cgagaaatcc tccgccagct tcaaggccgc atctttcttg
    85981 ttcagcccga acagacgggc ggtaaaatca atcacatccc cgtccgcctg acagccgaag
    86041 cagtggaacc ggcggtcaac cttcatgctg ggatgtttgt catcatggaa gggacagcag
    86101 gtcatcccgt tcctgccgag ctgtatccca taagattccg cagcctgcct tgtggggaca
    86161 gcctgcttca ccgcttcaaa cacattcgat tttctcacct ccagacagag aaaaaggcat
    86221 ccggttttca cagaaaatca gatgccttac aactctatat cgttcttttt ggtcggggcg
    86281 attcgcccct cacgttccca acgctcccgg ttatcccggt cagcattaat ttttgccttt
    86341 gccagaatat ccataatgga ttctttggct ttcttcttga cctgctcctt cccggcttgc
    86401 ttgacttccg gctgcatcag cgtccgctgg attttcgcca gagcgtgctg catggcgttt
    86461 ttgattttgg taatgacccc atccagacgc tcagcggcat actcacgttc cttctttgga
    86521 gctttgcgct ccggcgaaag cacccatttt ttcgattcct ccaccagacg aatatcttcc
    86581 ttgtgcgtct cctgccggac ggtatcggtc accacctcca ccgccttgtc ataggccgca
    86641 tcggaaacat catctaacag tgtctccacg tcctcaattt tgagcgtcag ttcttccagc
    86701 ttctgctcct gcgccgccag ttgctccttc tgtttcatca ggatataatc ctgtttttcc
    86761 agatagtccc gcccgccgta ggacggctcc tgatccagat gtagcccatg ccgtctggcg
    86821 atgtcaaaca gaatcgtccg gcaaaccgca tcaaaggtct gcttgcggtt gttgttccgg
    86881 cctttgggct tctcagggtt tgggagaggg atgcccagtt cttccagcgc cttttcctgc
    86941 tggggacaca gttccccgta gcggttctca cagtcaaaga cgtgccgctc atggatgtgg
    87001 ggcgtcccct cgtccagatg gagcgcccag tccaggatgt ggatatggga accgaagcgg
    87061 cgctcaaatt cctcataaaa ctcattgacg atggaaaaaa gcgtgtccgg cgggacggat
    87121 tctcccatcg tgccgatctg gtagatgctt tcctccgggc aggtcttgtt gtttttcagc
    87181 aagtcctcca cggtgcggtt gcgctccgtg tgccgggttt tctcattccg ggcgttctgg
    87241 gcctccacat ggccgccgta atgctcgttg tagtacatcc gctcgatttc ctcaaagctg
    87301 aaatccggct gctccgggtt ctcccggaac tcgtgtgtcg taaagccccg gtagcagtcc
    87361 cagtagacat tttgccttgc ccgttctgcg tcaatgtgtt cgctgttctc cacatcgaac
    87421 cggcggtcat tgtggcgggg attataggtg ccatgcttgc cggagcgccc attgtgtcgt
    87481 gtcagtttca aacagatttc ctccttcctg cgaagatgtt ctggggccgg ggaaggggcg
    87541 gcgaagccgc aaatcctgcg aattttgcgt caggtaatac ccagtacgag ttgacgcagg
    87601 catcaactct ccctgggcaa ggcgtttcac ccttgacccg ataatggctg ccgcccttaa
    87661 cctgccaatg ggcgttgccc cttgacccca gcagtgcgct gccgcccctg caccccggca
    87721 caaagggctg gctgccctct gtactcccgc accggcgaag ctggattcca ccgcagaagc
    87781 ggtgtttgcc agtttcaccg gctccgtatc cgcacatttg cgcccataag cggggaatgg
    87841 atacggaata cgcctgcggg gattgccggt caaaacagcg ggtgcagacc cggcattttt
    87901 tccgtaaacg ccccggtttc aggcgatttt ttcttccgcc cctaccacct gaaagccatg
    87961 ctcttttgcg taggcgctgg cggcggcttt ccgttcctcg ctgtacggcg gcaccagccg
    88021 gatcgacagc cgggacttat ccagcacata ggtcacgctg ccctccggcg tgctgcgctc
    88081 caaccggcac agcagcgggt acttccggct gaaatcagcc agcctgcgct tcaagctggc
    88141 gttgaaggtg tagacgctgg caaggttttc cgcctcgttc cagttgataa tggtttcttt
    88201 ctcatactta gacagcttcc tcatacagat cctcctcata atcagtgtaa gatttcagca
    88261 cacgcaggct gcgcttgagg cggcggtact cgtccatctc catccgcaga tggtggtaaa
    88321 aatcctcgta ccagttttcg cccacctccg tctccacctt ccgggccagc cccagcatcc
    88381 ggcgtttggc ctccgggtca accgtcagtg ccgtcagcca tttcagccgt gtcaccgtat
    88441 tgtggtggct gggacagccg taagcgtaga gaatcttctt ttctttcata ctcagtgtca
    88501 taatgatttc ctccgtttct ttgctgcgga gccatgcgcc ccgcatgatt gataaacttg
    88561 tttctgtctg ccggtctgcc tgcaagccgc tcctgcccgg aatttctccc ggcgtatcgg
    88621 cctctttggt gcgctcgatt tctgtcctgg cgtcacttcc ccggaggcca taccccttgc
    88681 agccggtcat tcgattttca aggttctgtg cctgtctgca agaaccagtt taccgaaaaa
    88741 agaggccctt tcccgtatat ccaaaacgtc ggaaaaacgc ttgaaatccg catatttcca
    88801 cgcttatgga atcgtgctat aatgggtgta atcactgaaa aacgataacg agagaggggg
    88861 ctttggatgt acgcaaagct gacaatcccg gagcggctca aagacctgcg ggtggtagat
    88921 aagcacctga cgctggaaca actggcggag cagaccggcc tgtctaaatc cgcgctggga
    88981 aaatacgaaa ccgatgacta caaggacatc agcccgtttg cgattgcaac gctggcggac
    89041 ttttacggcg tgtccaccga ctatctgatg gggctgacgg aaaataaaaa tcacccaaac
    89101 atagaacttc aatctctgca tctgagtgat gatatggtgg aacttttgag cagcggcaaa
    89161 atcaacaacc ggcttctctg cgaactggct acccacccga atttccggcg gctgatgata
    89221 gatatggaaa tctgcatcga ccagatcgcc aatatgcggg tggagcagat gaatctggtg
    89281 ttggaggcca cccggcagac cgtcatgaac aagtatgcac ccggagaaga tgacctctat
    89341 atgcggacgc tggaactggg gcaggtgcag gaaagcgatt tttacagcca cgtcatgcac
    89401 gatgatctgg acagcatcgt ccgggacatc cgggaagcac accgcaaaga caagaccacc
    89461 gccgacccgc agcccacgct ggatgatgtg aaggaaaaat ttgagcaggc catagggcag
    89521 ggcagcgata cagaaatgct gatccacgag ttctgcgata agttgcagat accctttgag
    89581 aagatttcct cggaggactt ctcggcgttc ctgcggatac tgagcctgtc caagcagctc
    89641 aaaagctcca acaatatgag gggaaaggcc agccccattc ctcccaaccg caaggccaga
    89701 cgtaagcgga agtaaaattt ccatatccgg aagcggcaaa aaagccatcc gccgattgat
    89761 tggcaaatgg ctttcgtgaa gctgtattct gttgtagtgg ttgtgcccag tttgggaaca
    89821 gtcactattg aagatgctat tctttgtctt tctgcgatac ctgtgcatgg gcttcctgct
    89881 gaacaagcag ccccgcagaa aagccatatt tgaagtggct ttcgttttcc tcacactggg
    89941 cgattgccac ctgctcccgc agttcttcaa ccagtgcata gtcctctttg ctcagacgct
    90001 ccgataaagt gtccatcagg gcggcgctgg ctttgactgc ctgcttgaac ctcggtgaat
    90061 cagcgaccac cgtttcacag ggataaaatc tgccgttata catttcttcc agaatcatgc
    90121 acccacctcc ctcagacaaa aatcatctca gacaggatga tttcctctac ccggctgcgg
    90181 atgctgttca tgcccccgac ccatgcaagc tggtcacggg ctttcagttc ctcggtgacg
    90241 ccctccgcag cctgcatctg cgagatgata cacgccagtc ggtcatcggc ctgctcgttc
    90301 agatcggcaa gatacgtcca gagttttccc gacagaagca gttcattgta ctggccggga
    90361 cggtgttctt gcagaaacgc cttgtgtatc cgaccccacc gcccgatggg gcggatttcc
    90421 tccgacaact ttagatcggg gatatagtag tctcccacca gcgtatagct gatgccgttg
    90481 tgatggattt tctttggtaa atgctccatg ttcgacctcc tgtattcagt tttttcagaa
    90541 tccagttgat cgtgtccctg ttcatgtgaa attcaaggca actgaactct tcacgaacaa
    90601 gtatggcata tccttaccag tcttttgata gtttaaacca aagctctttt gatttgacct
    90661 tgtttccgac gtgttataca ggtcgatagt ttcttttccc agtgtttcag acaattcttt
    90721 tagcgtagtt ttctccttgc caccaagaaa caaggtacta tcacagttac ctacgattgt
    90781 atcagcgtta tccttgtaga ttgcctttag ctgagattgt gcttgaagta tgatacttgc
    90841 tgaaatctct cttgaacgga ttgttgcaat taacttctca aacttaggaa ttaagccgat
    90901 attagcgaac tcatcaagta gacacctcac atggacaggt aatcgtccgc catatacatc
    90961 atcggcttta tcacataaaa gattaaataa ctgtgagtac ataatggata ctacaaagtt
    91021 aaatgtatca tcggtatcgg agataataac aaatagtgct gtttttctat ctcccagtgt
    91081 atcaagctca agttcatcgt cactcatcaa gtccctaagt tcctgaatat caaagggagc
    91141 aagtcttgca ccacaagaaa taagaatcga tttggcagtt tttcccgcag ccaatttgta
    91201 ctttttatat tgcttcactg caaagtgtgt aggttctttc ttctccagtg cttcaaagag
    91261 cctatctatc ggattcatat aggtttcatt atcttctctg acttctgaag catcaatcat
    91321 atcaagcaga gttgcaaagt tcttttcttc tcttggagct tcatagaaga tatagccaat
    91381 aagtgctgta tagtagagtt tctcagcttt cacccaaaaa tcttcacctg atttttctcc
    91441 ctctcccttg gtgtttgcga taattgtctg tactaatttg agtatgtcct tttcacttct
    91501 aagataagca aagggattgt atttcataga ctttttgaag ttaatggtat ttaggatttt
    91561 tatctcatat ccgttatctt caagcatctt accgcactca aggactatag ttcctttagg
    91621 atcggtcaca caatatgacg agtgcatctg cataaggttc ggttttacat aaaatctcgt
    91681 ttttccactt cctgatccac cgattacaag tacattctta tttcttgcat actttggatt
    91741 tgccggtctg ccattcatgg ttaatcgttc tgtttgcgta agtaggatat tgttttgaaa
    91801 cttttcatcc atatatggct ctatatcttt tttcgttccc catcttgctg agccatactc
    91861 tttcccctgt ctaaactttt tagcattttt ccctttggta tatacgataa ttttgattaa
    91921 aacagctact accactccca ttaaaatatc cgtaggatga atgcttggaa gaaagctcat
    91981 ggtgttaagt tccagtatac cttgaaatat tttgtctatt acatcgccac cagtatatgc
    92041 tcttacatga tgagaaaaga tattgccaac atagaaaaat gcaagatagg gaatgttctg
    92101 ctttagaaac tttgccttat cttgcacctt aaataagcct ttgatgtctt ttagtatctt
    92161 atctatcata ggctttgctc cttttgttta tttttgattt tctcttttga aatagagttt
    92221 ttagccatct ctttgaactt ctcaatattc ttgtgaatag attctttcct ttctgctttc
    92281 ttttctgatt ttgaaagagc gtgcttaaaa gctttatcca tcactttcat atctttggct
    92341 tgaaagaata cagagttttt acctgtctct ttatttttca tcactgaaaa tttaacaccg
    92401 tatctattca actctttttt aagttcttta agctcagctt cttccactgg gatttcttca
    92461 agctgtccct ttttaaccat atcttttagc tttacttcat ttccgttggc attgaccagt
    92521 ttttcaagtc ctccgaattt ctccgcttct ttcatcaatt tttttaataa gtttaataga
    92581 acttttccag taactttacc agcatttatc tccatattta aggtctttct tgctatttct
    92641 tcattgatca catcaatatc ctcctctcat atcatagctt acaagagccg aataataggc
    92701 atctattcca cttggtgcat tataagcggc ggtcaggaca aaagctctta tatttctaat
    92761 cctatattca ttttctctta atactcctac taagtactct aaatgtcctg aattaagttt
    92821 cctaaatctt tcctttacta cttgtacaga tatctttgtt tggttgatag taatgaaaga
    92881 ttcatcatct aataccatta catctgccag tatctttaat atttcatcaa actcttcagc
    92941 cacactctta ttcccaatac tcatatgttc ataatatcct gtttggtgtc gcaattcttc
    93001 taaacaattt tgatatatat ttttatagct tatatctatc ctccctccct tcatattctc
    93061 tgaaaataat tgattctttt ctttgatgga aggatggatg gaaatatatg ctgaattatt
    93121 tgtagtatta tttgtagtat tatttgttgt attctctggt aatggttggt gcaaattatc
    93181 cttttgcatt agtgcatttt gaacctgtgc attagtgcaa tctgcattat tgcattggct
    93241 gattttgccc ttatccattg gtgcattttg ccctaatgca ttgggcatag aattttttaa
    93301 tgcttctgtt tgtatttttt gttttttcaa atccatatcc atatataatt cttcaagttt
    93361 atcattatta attgtatacc attttgtttt atctcttgga tccttattgt aatttccaac
    93421 taaaagataa cctgcttttt ctaactttga aaaagttctt tttactgtat caaagctcat
    93481 atagtcaaag tcattttctt gccatgctcg aattgaatta tatgtccagt atttaccatc
    93541 atgataattc tttcctgatt ttttatttat ttctatccaa taattaatct gctgtagtat
    93601 gagtgcttcg tttaatccta tttctctagc aagagtttta ttcgcaacta taggttgttc
    93661 atcaaataaa tacataactc atcaaacact cctttctttt tttcaaacaa aaagacgata
    93721 gttatttcta tcgtctaaaa tcatatataa atatcatttt ctaaatagag cgtattgctt
    93781 ctttcactcc cgttaaaacg gctataacag ctgttccaac cattggtatt ccgtatgggc
    93841 ttaacaaaaa tcctaatatc aatgcttcta tccctatggt aacctctttt tgtaaaaaag
    93901 atgctattgc tccaaatatg caaaacatca tcaacaggta aagtattgct gttcctatgc
    93961 caagtaaaaa tgaaagaaat gcaatgagaa tacttaacgc tatactaatt ggaaataaga
    94021 taatttttaa tatccatctc atatatactc tccatttata ctaaatcatt ttaaaatgtc
    94081 ttaaagcgtc cattatagct tcttcttttt caggcgtaca ctgtgggata gcctgattgt
    94141 cttttttaga tttattataa tgctctctca gttcaattcc acatttcttc ttaatctgtg
    94201 caatataaag tgtagaaacc tttagcccaa atttttctaa tacatactcc ttaatttgag
    94261 catatgttgc tttgctctct gcacttgtca aatcaagctc atccagctta atttcaacat
    94321 ctatatgctt atcgacatca agtttggaca ataacgctac cgtctccaca tgtgtagaat
    94381 gagggaacat atctacaggt tgtgcctcaa cacatttaaa tccgtgaaca tttagatagt
    94441 ctaaatccct tgctaaagta gaaggattac aagaaacata gacaattctt tccggattca
    94501 ttgaaacaat agtctctaat accttttcgt cacatccctt tctaggtggg tctacaacta
    94561 ctacattggc agtcttaccc tctctataca tcttaggtac aatttcctct gcctttccaa
    94621 cataaaattc agcattatgt atattgttta atttagcatt tatcttagca tcttttatgg
    94681 catcatctat aatttctatt ccataaacct ttttagcctt ttgtgccaaa aataaagata
    94741 ttgtacctat cccacagtaa atatcaaaaa cagtatcagt atcatttaaa tttgcatatt
    94801 caagagcctt atcatacaat actttagttt ggacagggtt tacttggaaa aatgataatg
    94861 gtgaaatctc aaacactaag tcacctatat aatcgtttat ttttccatct ccatatataa
    94921 ctatattttc tcttcctaga atagcattcg tatctttttg atttacattt acaaccaaag
    94981 tcttaaatcc aggtatattt tccttaagca ctgaagctaa ttctttaaga tatggaagtt
    95041 tgtttccatt tgctactaat acaaccatta cttctttagt tgtaaaacct atttttgtta
    95101 ctaaatgcct aatcaacccc gtgtgagtct tttcatcata tatacttacc ttataggccc
    95161 ttatatatgt ttttattatt ttaacaattt tatcatttat ctcatgttgt attacgcatt
    95221 tttctgtcga tattacatca tgagtcttct ttttatagaa gccaataatt ggaataccat
    95281 tattcttttg tattggaaat tgtgctttat ttctatatct atatggatta tccattccta
    95341 tagtgtcatg aacttctaca tcctctaact tacctattct cgaaagtact tgtttaactt
    95401 catttgtttt catttcaagt tgtttattat aatctaaatc ttgtatctga caccctccac
    95461 aatccctaag attgtcacta cacactcttt tcaccctgaa tggagacttt tctattatct
    95521 caacaatatc tccctcagca taatttttct ttactttatt aatcctaact ttaactttat
    95581 catgtattaa tccgccctct acaaaaactg taataccatt gtactttcct actcctactc
    95641 cgccttgacc aatgtctact atatctacaa tatacatctc gtttttcgaa agcataaatc
    95701 accctccaat caatctatta tatttaaatc tttacaaact tttttcttta aatttatatt
    95761 aaaatattgc tattaattaa actatatttt ttactaagct acaatatttt attttaccaa
    95821 aaaaaaagga gcttataaag ccccttagta aataaattta ttatttttct tataaaactc
    95881 tagttgaacc tctatatacc acgcctcttg atgcatccac agttacaact tctccatctt
    95941 ttactagatt tgttatatca gttgcagaca caataactgg tatatctaaa tttataccta
    96001 caatagctgt atgtgatgtc attccaccat tctcagttac tacagctcct gctttttcta
    96061 tataattgtt catttcagca tcagtagcag tagaaacaag tatgtcgcct tcattaaagt
    96121 ctacacaagc atttccattc tttattatac gaactttacc ttctaccgtt tgagtaccta
    96181 cacctatacc ttgcacgatt tcttcgctta ttacatgaac ctttattaaa ttagtagttc
    96241 cacttactcc tactggtact ccagcagtta taactactaa ttccccatta tctatataat
    96301 cagcttgtct agctgcctca attgcctttt ctataacttc atctgtattt cctgcaacag
    96361 aagacttaac tggatatact ccccatgtaa gagctaattt attcatagtc ttttcattat
    96421 ttgtagtagc tattattgga gattttggtc taaatttaga taccattcta gcagtatatc
    96481 ctgaagaagt agatgttatt atagctgatg catttaaatc tactgctgtt gtacaagttg
    96541 catggcttat tgcatctgtt acagtaacat tgttagtacc attttccttt agtaatctat
    96601 cataatctaa agtctcttct gttctttttg ctattgtagc catcattttt actgcctcta
    96661 caggatattt tccagcagca gtttctccag ataacattat cgcatctgtt ccatcatata
    96721 tagcattggc aacgtctgta acttctgctc ttgttggtct tggatttctt atcatagaat
    96781 caagcatttg agtggcagta acaactggct ttgctaattc attacatttt tttatcatca
    96841 ttttttgaac tattggcatc tcttcagttg gtatctcaac acctaagtca cctctagcca
    96901 ccattatacc atcagaaact tttaatattt catctaggtt ctctacacct tcttggtttt
    96961 ctattttaga tattatttgt atatcagttg cattattgtt ctctaatact tctcttattg
    97021 ctagtacatc agatgccttt cttacaaaag aagcagctat ataatctatt ccttgactta
    97081 ttccaaactc tatatcactt atatctttag gagttattgc tggtaaattt atcttaacac
    97141 caggtacatt tactccttta tgatttttaa ctattcctga attttcaaca acacaaacta
    97201 tatcttctcc atttatttct tttactctta agccaactaa accatcatct attagtatag
    97261 aatctcctga tttaacgtct tcagcaagac ctttatagct tactgtacac atttctttag
    97321 tccccataat atctttcata gttatagtga acttttgccc ttcttctaaa aatacctctg
    97381 ggtcttcaaa gttacctgtt ctaatttctg gacctttagt atctaataat atagcaactg
    97441 gcttatttaa tttttctcta actttctttg ccatatcaat tctttcttta tgttcttcat
    97501 gcgaaccgtg agaaaagtta aatctacaca catttagacc attttgcata agttgagtta
    97561 aaatttcctc actttgtgat gctggaccta gtgtacaaac aatttttgtc ttctttacat
    97621 tatttaacat atttgctcct cctgagatat tattccacag atttattttt aatactaaaa
    97681 cttatataga taatattttt gccatctcat aagcttcttt atcaaatact ttcttttgag
    97741 ctaaagcttc acttatttct aaatcaatta ttttgttttc ttttattcct acaactctag
    97801 ctgattttcc atctaataat aattctactg ctcttactcc aagtctactt gctagtattc
    97861 tatcagatac agttgggctt cctcctcttt ggacatgccc caatacagtg actcttaaat
    97921 ctgctcctga ctctttttta agttcctttt ctaaatcact agcacttccg actccttctg
    97981 ctaaaacgat tatactatgt ctcttacctc ttttttgagt agtctttaat cttagagcaa
    98041 cttcatctac tgtaatttct acttctggta ctattatagt ttccgctcct cctgcaagac
    98101 ctgcatataa agctaaatct ccacagtgtc ttcccataac ttctactatg ttaactcttt
    98161 catgagatga tgatgtatct cttatcttac ctatagcatc tataatagta ttcattgcag
    98221 tatcaaatcc tatagtataa tctgtatatg ctaaatcgtt atctatagtt cctggtatgc
    98281 ctatagctgg gaatcctaag tcactaagtt tttgggctcc tgcaaatgaa ccatctccac
    98341 caattacaac taagcaatca attttatact ttttaagaat ttttactgct tttaatctac
    98401 cttcttctgt tttaaattct tcacatctgg aagattttaa tatagttcct cccctgtgta
    98461 taatatctcc aacagaagat aagttcattt cagttaaatc ttcttctagt aatcccttat
    98521 atcctctatt gattccatat actttgcatc cataatatat tgctgatctt acaaccgctc
    98581 taatcgcagc attcattcct ggagcatctc ctccacttgt tagtaatcct atagttttca
    98641 ttttttacct ccttggattt tatgtcaatt ttttattata atcattgtta ttgtattcta
    98701 atggactttt tttgtcccta tatcactttt taatcccatc aagactaaaa aaattaaatg
    98761 tccttaaatg tccattttgt gatattatat cacaaaacgg acaatatttt tcatattatt
    98821 ataatatatt tagattttta tataaaaaat caagctttta cttttatgtt atctttagga
    98881 agtaactctt ctaagttatt tataaattca tcacatatac aagtcaatgc cccggtcatt
    98941 ttatatgctt tacgtttacc atttatattt tcatccatag ggtacaagta tatactgtca
    99001 ttacctggat attgtttggc tatttctaca atattattag ttgtatcagt atcagacata
    99061 ctatctattt tcaaatacaa ttttttacca ctttctggct taatattttc tacatttcta
    99121 gttcttcctg aattgtagtt tctatctgca aagtcagtat catcatttat atcttttatc
    99181 tctctagcta taagttttgc attttcgcct tcttttatac ttaatgttcc ttttacatat
    99241 attatattat cttcattcaa aatgacatta tacttttgta ataattgagg aaaaactatt
    99301 atttctatag caccatacaa atcttctaat tcaataaatg ccataatttc atttcgtttt
    99361 gttgttttaa tagttttagt tacaatcatt ccacccatta taacatctgt ttcattcatt
    99421 tgtaggtatg actcttcttc ctcttttaat gaatttaatt ttccattatc catagatgtt
    99481 ttttcttgta gttctttttc aaattgtgat aaaggatgtc cacttacata cattcccaag
    99541 acttcttttt caaggttaag tctctctctt tcttcatact cttgcctttt aggtaaactg
    99601 tatatttgtt gaaaatcact atcttcctca ctatctccaa aagcatcaaa taaagaaatt
    99661 tgaccttgaa catttttctt tctatccata gatacacttt ctaataaact ttcataacca
    99721 gccatcagac tagctctatt ttcacttata ttatcaaaag ctccacattt tattagactt
    99781 tctattactc tcttatttgt atctttttgg tctaatcttt tgactaaatc tactaaatct
    99841 acaaataatc cattagattc tctttcagcg attatattgt ttattatatt tacaccaaca
    99901 ttttttacag ctgctagacc aaatcttata ttgtcgcctt caactgaaaa ctttgaaaaa
    99961 cttttgttta tatctggagg taatacatct atttctagtg ctttacattc tcttatatac
   100021 tcaactacct tatcagtatt tcccattaca ctggttatca atgctgccat aaattcaact
   100081 ggataatatg tttttagata agctgtctca tatgctaaaa ccccatatgc agctgcatgt
   100141 gatttattaa atgcatatct agcgaagtct atcatatcat caaatatttt attagctatt
   100201 tcctcttcta caccatttct gatacaccct gcaatttcta tattaccatc ttcatcaaat
   100261 ttaccatgaa taaaatattg tctttcttct tccatcacgt ccatcttttt cttactcatg
   100321 gctcttctaa ctaggtcact tcgtccgtaa ctataaccac ctaaatctct aacgacctgc
   100381 ataacctgct cttgatatac caaacaacca tatgtaactt ccattatagg ctttaatttt
   100441 tcatgtagat atgttacatc ttttgggttg cttttatttt ttatatatgc aggtatagaa
   100501 tccattggac ctggtctaaa tagggatatt cccgctacaa tatcttcaaa attgtctggt
   100561 tttagctgtt tcataaaact tctcatgcca gcactctcca attgaaacac ccctagtgta
   100621 tttcctgatg aaagcatttc atatactttc gggtcgtcat aatccatctt tgaaaagtct
   100681 attttttctg tgtagttttt tataactcta tttttttcta ttaaatcaag agtatctctt
   100741 ataactgtaa gagttcttag cccaagaaaa tccatcttta aaagcccaag ttcttcaagt
   100801 gttgtcatag taaactgtgt tgtgattgca tcttgatgtt tgtacaaagg tacatattca
   100861 tctacgggat tttttgatat aacaactcct gctgcatgag tagaagcatg tcttagcatt
   100921 ccctctatct gttttgatat atttattatt tcttttgttt ccgggtcttg gtcatacaat
   100981 tctttaagat taggatttgt atctagggcc ttatctattg tcattcctaa agcaaatggt
   101041 atttccttgg ctaccttgtc aactttattg tagcctatat ccaataccct tccaacatct
   101101 cttattgcag cttttgcacc cattgttcca aaagttatta tctgggctac atggtcatca
   101161 ccatattttc tctttacata atctataact tcttctcttc tctcataaca aaaatctata
   101221 tctatatctg gcatggatat acgttctgga tttaaaaaac gctcaaataa tagagagtac
   101281 tttattgggt ctatatcagt tatcttaagt gtatatgcta ctatcgaacc agccgcacta
   101341 cctctacctg gtcctactat aatattattt tctttagaaa aatttataaa atcccaaaca
   101401 attaaaaaat actctacata acccattttt tcaattacat ctaattcata atttaatctc
   101461 tctagtatct cattgctagg attatcatat ctctctttta atccattaaa acacaactcc
   101521 cttaaataag tttctggtgt atatccttct ggaacatcat acttaggaag atgtatagta
   101581 ttaaaatcaa actccacatt acacatatca gctattttca cagtattgtc aatagcctct
   101641 aatgcgtatg gaaataattc ttccatttct tctcttgatt ttaagtaaaa ctcatcacta
   101701 ccaaatctca ttctatttgg gtcatttaat gtttttccca tttgaataca cataagaaca
   101761 tcatgtattt tcgaatcttc tttatttaca tagtgaacat cattagtagc aactagtggt
   101821 ataccagtct cttttgataa ttttactaaa ccagagttta cttctttttg ctcaggtaaa
   101881 ttgtgatctt gaatctccaa aaagaaattt tcttctccaa atatgtctct gtagtcaaga
   101941 gcaaattgtt ttgctttttc ataatttcta ttcattaaag cacgtgctac atctcctgca
   102001 aggcatgcag aaagtgctat aatccctttg ttatgttttt taagttcttc catgtcaact
   102061 ctaggcttat agtaaaaacc ttctacgtat gaagttgaaa ctatttttat taaattttta
   102121 tatccttcca tattcttagc taacagaact aaatgtcctt gatatttgtc atagtttggg
   102181 tctttatctc tcaatccacg tgcagctgta tagacttcgc accctataat tggctttatt
   102241 ccttctttta tagctgtttt gtagaaatct ataacaccaa acatacaacc atggtcagtt
   102301 atagctattg agctcatgtt tagttcctta gcccttttta taagtttttt caccctcgaa
   102361 aacccatcaa gtaaactata ctcagtatgt acatgaagat gagcaaaatc tttgttcatt
   102421 aaatcacctc ctgctttata attttaattt taccacaaat atatgtccta aaacaaaaac
   102481 agagactttt atctcaaaat aggaattaac ttcaacatat accattatat gttataaatt
   102541 aatgcttatt ctgagattgt cccctcaatt tattgctatg attttttttt caaatctgtt
   102601 gcaatttctt ctatttttct aagtctatga ttgactccag attttcctat tggtggttct
   102661 aacatctctc caagttcttt gagagtcata tcctcatact cgattctaat cttagctatc
   102721 tcttgtaaat tttctggcaa actgctaatt cctatagtct cttgtatgag cttaatattt
   102781 tctacttgtc ttactgctgc atttactgtt ttagaaaggt tagctgtctc acaatttact
   102841 atcctgttta cattatttct catttctttt actattttag tattttgaag acttaaaaga
   102901 gcgtggtgtc ctcctataat actcaacaaa tctgatattt gttcactctc tttgatataa
   102961 acaacgtgat tattttttct agccacaatt ttactattaa aacctaaaga gtttataagt
   103021 tcttttagag aatctgcaaa ctcctcatta ttagttacaa attccatatg atagttcttt
   103081 tctgggtcgc ttatagaacc tccaccaaga aaagctcctc ttatgaaagc tctcttacat
   103141 ccttcatgct taattaagtt ctctgaaatt ttgtttatag taaaaaagcc ttctttatct
   103201 tcaagtatac ctaacttttt taataacatt tctgaaccca tttcgcttgt taccattaat
   103261 acataactgt tatttctctt tagcatttga ttcttattta ctgagattgt agtattgata
   103321 ttaaaattct tttttaataa tttaaatact ttacgggcta ttgaatttaa ctctgttgtt
   103381 atctttagat ttagcttctt atatccaacg atttgtatac ttccccctga tttaactaga
   103441 gctgataatt cagctatatt acaacattca ttcccagata taactcttgc tagttcattt
   103501 ttggtttcag ttgaaaaaga catatctatc acctattaac taatttttct ttaacctttt
   103561 ttttatttct tgtaaggcaa cctttattat ctccttttca tcatcatacc tagctaggtc
   103621 taccactcta tctagatgga taaatttagc atcaataaag ccttcctctt tttgtggaat
   103681 agtatccata ttctttgctt gcatcaaata ccaaaaaact gttttatgaa ctgctctatt
   103741 ttcatcccag ttttctttga atgtatagtg tatttcacct aaatatttca atatatctgc
   103801 ttttactcca gtttcttcac ttacttcacg taatgctgcc tcttggttat tttccccttc
   103861 ttctactttt cccttgggta acacccaatc tccattgaac ttccttagta aaagaatcgt
   103921 attgccaaac aggactacac caccagcact aacctcttct ctcatcgatg ttcactcctt
   103981 aaaactaaca taatgataag gatttctaca caatttttta aaatcctttt ttactaactt
   104041 ttgttgtaat tatgatttag ggctaactca ataactatgt tagatatata ctttgcatca
   104101 tgtcttatat aattattttt tatttcaatt aaattcttct ctacggtttt tatacccatc
   104161 tcttttaatt tatctttttg ctttttatct aacaagactt gctctgctcc atcttgttta
   104221 tataagtcaa gcatttcttc tggcaatatc tcattatttg cgattacata atctattaaa
   104281 ttctcatcag tgtgctttac tatagcatta acatgctcta atacattgta cccttctgtc
   104341 tcacctggtt gagtcattat atttgctata tatacttttg gagctacaga cgatttaata
   104401 gcgtctacaa tcccctctac aagtaaattg ggtattatac tcgtatataa gcttccaggg
   104461 cccataatta taatgtcagc atcgtaaata gatgcaataa catcctttaa tggtttgaca
   104521 tcttttggat ttaaaaaaat tttatcaata gagctttttt gaatttttga ctcttcaggt
   104581 atactagatt ctccatttat tatattgcca ttttctaatt tggcaactaa atttacatct
   104641 tccaaagtta ctggtaaaac tcttcctgtt atagcaaaaa tttcacttaa tttatataca
   104701 gctttttcaa agtttccata caacccattc atagcagcca aaaacaaatt tccaaaactc
   104761 tgacctttta aaagcccttc tgtaaaccta tattgcataa cttcattcat tgttggctct
   104821 atatttgcaa gtgctaatag acagtttctt atgtctcctg gtgggagcat tcctaagtct
   104881 tctctcaata cacctgaacc tccaccatca tcagcaacag ttacaattgc agttatattt
   104941 tgcgtagtgt gtttaagacc tcttaaaaat actgattgac cagtacctcc acctatcaca
   105001 accacatttg gttctctatt ttcaacaata gacctttgaa atagttttac tttttcattt
   105061 tttgcttttt tatatataaa taacgataca attaatgcaa tccaacctaa aattcctaca
   105121 ataataagta atttagccat gtttgcctcc attatcgcaa catagagtct ctatgtttct
   105181 ttacaactct atatccctta ttagataaat cctccgctat aagatttgtt atagtaactg
   105241 acctatgtct tccacctgtg catccaacac caattactag atgttgtttt ccttcatcta
   105301 tatattgagg tactaaaaaa tgaatcatat ctaaaagttt cacataaaat tcttcactga
   105361 ttttagaatt cataacataa tctctaactt ctttatcatc accagtttta gctcttaact
   105421 cttcaacata atagggattt ggaagaaatc ttacatcaaa tactaaatct gcatcagcaa
   105481 gtataccatg tttaaatcca aaagatacta cagaaatagt taggtttgga ttatcttcac
   105541 cagaagaata tattttcttt atttcttcct taaggtcttt aggtttcatg ttagttgtat
   105601 caattataca tgtagataac tcctttaaag gttccattat ctttctttcc atttttatac
   105661 cttctggaat ctgcatatct tttgccaatg gatgatttct tcttgtcatt ttatatctct
   105721 ttaacaatac atcatcatta cagtccaaat ataccatttc atattcataa ttttcttttt
   105781 ctaaataatt taagctttca tgaagcgctt caaaaaactt tctccctctt atatctatcc
   105841 ctagagcaac tttatcaata cttgaatttg gttgataaca taattctgca aatttagtta
   105901 tcaaagcagg aggtagatta tctacacaat aaaatcccat atcctctaaa gctctcattg
   105961 tctcactttt tccagatcct gaaagacctg taactataac aaatttcatt gctaactcct
   106021 cccttttatc ttatgtttat tatattataa tgttttctac taacgatata tccagattag
   106081 agtcagatat agtcttcata gctagtttaa aatcaccaac tctttctgga caatgtgcat
   106141 ctgagcctat tataaattta ttttctagcc cttttatttt atttaattga tttacattca
   106201 aaaaagaatg gctactattt atttcaagtc tagtatttgt cttttttgct gtctttgcta
   106261 cttcttctat atacacatcg cctttatctc ctggatgagt aattataaaa atatcattat
   106321 tacttatcgc atttattaca gcttttgtat tgtattcttt tgctttttca gttttaaaaa
   106381 tatagttatt acaatgattt aataagcttc ttaatgatgt tggagtagaa ccaaaatgat
   106441 atccagccat aatataatca aaatctctaa taaatttatc atccatatct atattgcctt
   106501 tatcatctaa tatgttacac tccataccta aaagtatatt tatatcattg tacttatcat
   106561 ttaaataatc tacttcttct ctcattttga gaatatcttt tttctttaca ccatatgcaa
   106621 tatgtttata gctatggtca gatattccta ttgtttttat tcctttagaa atggctacct
   106681 ttacattatc ttcaatagtc cctttgccat gactatataa tgtatgtgta tgataatcag
   106741 ccagtatttt catttgttaa tcctctccaa gtattttgac ttcttcttcc aacataaccc
   106801 caaacttggc atatacagca ctttttataa catatattaa atccaaaata tctttagcac
   106861 ttgcttctcc ttgattgact acaaatccac aatgcttctc agatacttgt gctcctctta
   106921 aagtaagacc tctcaatcca gtttcttcta ttaatttacc tgcaaaatat cctgttggtc
   106981 tcttaaatgt acttcctgca ctcgcaaaat ttaatggctg tttagttatt cttcttgtcg
   107041 ctaaatcatc cattaaactt tttatttcat cataatttcc ttcttgtaat tctagttctg
   107101 ctgataaagc tatatatccg tttttcgata ttatactttt tctataccca aattccatct
   107161 gttcatttga taattcaaat atattgcctt ccatatccat cagtcttact gacttcacta
   107221 tgtccttcat ttcaccacca tatgctccag cattcatggc tagtgctcct cccaatgtac
   107281 caggtattcc tgatgcaaac tcaaaccctt ttaattcttg cttttggaga gctttaccta
   107341 aaactgataa taaagctcct gactgagcag tcatcctagt atcatttatc tcataagaat
   107401 tgaaattatc agctaattct attaccactc ctcttattcc accatcttta attaaaatgt
   107461 ttgaaccatt tccaattatt aaatacggaa tagattcttc ttttaccaac ttaagtacat
   107521 tttttaattg ttcttcagtt ctaggtctaa ctaatatatc tgctggtcct cctaccctaa
   107581 atgaaatatg ttttttcata ggttcatcga cttttatatc ctctttactt aatatattta
   107641 ataaatttat atatatatct tgattattca ttgtatttcc tcccaaatta tactgaactt
   107701 tagctgtcat tattatttaa attacattag tatatagtat taactatatt caataatata
   107761 tgattttgct tatcatatgg attttatatt ttaagcttct taattacaaa ctatattcaa
   107821 taaatatata ataaagtaaa aaaaaaaaaa taacaacata taaaagaata taaataattt
   107881 aaaaaaagca tcaatatcac tgatatcaat gctttaaaag gcaatttaat tcgtattatt
   107941 tatctaacta tttttgacat agcaaagata ataaatccct ccaactacta tggaacctcc
   108001 aacgatattt ccaagcgtta caaataccaa attagttata aattgaacca tagttatatt
   108061 tgctcctaat gccattccca ttggtataaa aaacatgttt gcaacactat gttggaatcc
   108121 gcataataca aataacatta ttactgtcca acatgaagcc aattttgaca ttatatcttg
   108181 agatgctgta gccatccata cagctaaaac gactaaaata ttacaaagta ttgcttttaa
   108241 aaacattgat gctatagttg aattaacctt agcttctgcc acagctatag cttttgtagc
   108301 tgcatctcct gtcaatgtag aagaataaaa cacaagtgca actagcagaa ttgaacctac
   108361 taaatttgca aaataaacca gtccccagtt tcttaacatt tttcctaatg ttattttttt
   108421 gtccataagt gcaatagcca ttaaggtgtt tccagtgaat aattctgctc ctgccaccac
   108481 tacaagcata agacctactg gaaagaccat agcacttaaa aagctagcta cccctgggtc
   108541 tatcttgcca aaagtttgac taactatcat actccccaat gccccaaaac ctataaatgc
   108601 tcctccaaat aaacctaata gaattgcatt ttgtgtcgaa atgtttgctt ttttaatgcc
   108661 tgcacttata gttgcttgtg cagtttcccc aggtgtcaag aatcctttac tcataaatcc
   108721 ttccccctta aaaattatac tttcccttgt ctttttatgg caataattat ataataacaa
   108781 tatgatatat aataaatttt attaacataa aaaatatact atatacttat atatacttgt
   108841 ctcatataat tatactattt attatataac aactttgtta atttcgaaat aatttatatt
   108901 gaatttgaaa aatttacctt ttgattattt attttacttt ttaattattg aggtattata
   108961 tataatagat atatgtttgt gttattatat ataattactt attttaataa atatttgaag
   109021 gagggaattt tatgtttgat atatcatttt tcgaaatgtc aatatatgaa atagcagtta
   109081 ctacaatata tataattaat ttcatggtta tactaaacct tatctttaga gaaaaaagaa
   109141 acataaatac aactttaaca tggcttctta tattagtatt gattcctgct cttggattca
   109201 tactttatat agcttttggc agaaatattt caaaaaacaa tatgtttaga ttgaaagaaa
   109261 aggatgataa gataatcaaa agtaatatac tagatactca ggttaaactc caatctacat
   109321 ctgaaattga ttcagatata catcaacata aggatatgat ttatgcattg gctaattcaa
   109381 ataatgctca ttataccaat aataacgatg tgtggattta tgctgaatct agtcaatttt
   109441 ttaacagtct tcttgaagaa cttaaaaaag ctaaaaaata tataaacata caattttaca
   109501 ttttcaaaga tgacaaaatc ggaactgaaa taatagacat tcttatagac aaagctaaag
   109561 aaggtgttga agtaagactt ttatttgatg cagttggtgg tagaacacta aaaaatagta
   109621 cactttccag acttaaagaa agtggtgtta aagttggaag cttcttccca tcattcttga
   109681 aaattgtaaa ctttaactta aactatagaa atcaccgaaa aattgttgtc attgatggta
   109741 aggtaggatt tgtaggtgga tataatgttg gtgatgaata tttaggtaga aatccaaaat
   109801 ttggtctatg gagagataca catactaagc ttactggtga ttgcgtaatt gacctaaata
   109861 tgagattcat ccttgattgg agatatacaa ctaaagaaga tttagattta gaaaagtact
   109921 ttatagaaga agatacaaat tctaatcatc cttctgaaaa tattgggatt cagatagtat
   109981 caagtggtcc agatatatca gaacttgatg agattaaata tggttacctt aaaatgattc
   110041 agaaagctag aaagtatata tacatacaga gtccttattt aatacttgac tcaactttta
   110101 tagatacttt aaaaatagct tgtttatctg gtgttgatgt gagagttatg attccttcta
   110161 aacctgacca tccctttgta tactgggcat catattcata tgctggagaa cttttaaagt
   110221 ttggagctaa aatctacact tatggtcaaa atgcattttt acatgctaag acaatagtta
   110281 tagatgactc tatatgctct ataggaacag ctaatatgga tatcagaagt tttgagctta
   110341 atttcgaagt taatgcattt atgtactctt caaaaaaagc attggaacaa agaattatat
   110401 ttgaaaatga tattttaaat tctaaggaaa taacattaga tatatataat tctaggtcta
   110461 cttatataaa aatcaaggaa tcaatttcaa gactattatc agcagtttta taaatctttt
   110521 attttataaa aattttacat tttggtttat tttttaaagt tttttatatg tattattttt
   110581 tttttattga atttagctca ttttttttat tttttttaac tattctgaat tattttatat
   110641 tataatagac tagtatagtt tttattttta ataggtaact tttttgcatt gtttttataa
   110701 ataaagaaat tgttgtatat tattctttct ttattgttct ggttttgttc acccacataa
   110761 tgttggggtc aactcatggt taattatttt atgaaaaata ataactttaa aaagaaaagg
   110821 gggatttgtt atgtgcgatt ttatttcaca caacaagcaa ttatttgacg aactagatat
   110881 atttattgac tctcttacaa caaaggaagg tgcgttaata caagttctac atgaagccca
   110941 aggtatattt ggatatcttc caaaagaagt tcaacttcat gttgctagaa aacttggagt
   111001 agctcctgca aaggtatatg gggttgttac attctattct tattttacta cagaacctgt
   111061 aggtaagtat aaaatcagtg tctgtctagg aactgtatgt tttgtaaaag gtgctgacaa
   111121 aatcttaagt gcttttgaaa aacagcttgg cataaaagtt ggagaaacta ctagtgattt
   111181 taaattttct ttagagggtt taagatgttt gggggcatgt ggtttagctc cagttgttac
   111241 tgtaaatggt aaagtttatg gtaaagtgaa acctgaccaa gtaagcgaaa tattagatac
   111301 ttatagagaa ttagaattga attgttaaga ggggtgaata aataatgcgt aaagtaaatt
   111361 catttgatga attaaaagtt ttagctgatg agctgaaacc taatcttagc ttaagaaaaa
   111421 attattctaa ggaaaatgta ttaagaagag aattacttgt ttgttgtgat actggatgta
   111481 cctcttcaaa cagtctagaa atagttagtg aattagaaaa tgaaataaag aaatcaggaa
   111541 tccaagataa agttagtgtt cgtttgacag gttgttttgg tttctgtgct caaggtccta
   111601 ttgtaaaagt ttatcctgat aacgttttct acgtaaaagt tgagccatct gatgctgaaa
   111661 agatagttca aagccactta attagaaata cagttgtcga ggaattatta tatgaggaag
   111721 aatctttaag taaaaaagtt gaagaacaag aagaaatgtc tttctacaaa aaacagttac
   111781 gtatagcttt aaaaaattgt ggtcttatag acccagatag tatagaagaa tatattgcca
   111841 atgatggtta tttagctcta ggcaaatgtt taacttctct tactcctcaa gaagttattg
   111901 cagaggtaaa aacttctggc cttcgtggta gaggtggtgc aggtttccct actggctcta
   111961 aatgggaagc tgcttcaaaa aatccagctg gtccaacaga taaaaagttt gttgtatgta
   112021 atgctgatga aggtgaccca ggtgcattta tggatcgatc tgtacttgaa ggtgaccctc
   112081 atagtgtact agaagctatg gcaatatgtg gatacgctat aggttctgat acaggataca
   112141 tatacataag agcagaatat ccaaaatcta tagaaagatt aaaagtagcc atagctcaag
   112201 ctgaaaaata cggtttactt ggcgaaaata tcttaggcac tggatttaac tttaaattag
   112261 aattaaaata tggtgcaggt gctttcgttt gtggtgaagg tacagcgcta atgcattcaa
   112321 ttgaaggtag acgtggtgaa cctagaatga aaacttatag ttcttctaag agtggtctat
   112381 ggaaatctcc tacttgctta aataacgttg agacttttgc taacatacct gcaattatac
   112441 ttaagggtgg agattggttt gccaacttag gtactgaaga ttctagtggt actaaagtct
   112501 ttgctcttgg tggaaaagta gaaaatgtag gacttgttga agttccaatg ggtactactt
   112561 taagagatat tgtatttgaa attggtgggg gaatccctga aggtaagaaa tttaaggctg
   112621 ttcaaacagg tggaccatct ggtggatgta taccaactga acatttagac actcctatag
   112681 actttggttc attaagttct atcggttcaa tgatgggctc tggtggtatg cttgttcttg
   112741 atgaatctga ctgtatggta gatatagcca agttcttcct tgagtttact gttgaagaat
   112801 cttgtggtaa atgtacacct tgtcgtatag gtactacaag attattagaa atattaacta
   112861 aaattacaga aggtaatggt actctacaag atttagatga cctagaaaac cttgctgaaa
   112921 ctatacaaac tgcttcatta tgtggtcttg gtaaagctgc tccaaaccct gttttaagta
   112981 ctcttcaata tttcaaagat gagtatatag ctcatgttgt agataagaaa tgtcctgctg
   113041 gtaaatgtca gaacttactt tcttacttta taacagatga ctgtaagggt tgtacaaaat
   113101 gttctagagt gtgtcctgct ggttgtataa caggttctgt taaggaacaa catacaatag
   113161 atacttctaa gtgtctaaaa tgtggtgctt gtatagataa ttgtacattt aacgctataa
   113221 tcaagaaata acttatttgg aggaggaata acaatgagtt tagttaattt aactattaat
   113281 ggcaaacacg tttcagcacc tagtggaact tctatcttag atgctgcgaa attaataaat
   113341 ataaaaatac acaacctttg tcatttacat atgaacgaaa tagataagct tgacacttgt
   113401 gcttcttgtc gtatttgtat ggttgagaca gagagaggct tagttccagc ttgtggaaca
   113461 gttataaagg aaggtatgaa agttcagact aatagtgcta aagcattaaa tgctcgtaga
   113521 actattgttg aattattgtt atcagaccat ccacaagatt gttttgtctg tgaaaaaaat
   113581 ggagattgtg aattacagac tatagctgct gatttaggag taagaaaaat aagatatcaa
   113641 ggttccaaat cttttgcagg taaagatact tctactaaat ctttagttaa agaccattct
   113701 aagtgtatat tatgtagaag atgtgagact gtatgtaatg acatacaaac agtaggagca
   113761 ttatctggag ttaatcgtgg atttaatact ttagttagta cattctttaa ctctgatatg
   113821 gttgaaacag agtgtacatt ctgtggtcaa tgtatatctg tctgtccaac tggagcatta
   113881 acagaagtag ataatgtacc taaactttgg gatgttttaa ataaaaaaga aaagactata
   113941 gtagtgcaag ttgctcctgc tgtaagagtt gctattggtg aagagtttgg attagaacca
   114001 gggtcaatct ctacaggaaa aatggtagct gctttaaaag cacttggatt tgaacatgta
   114061 tttgatacaa actttggtgc agattttact ataatggaag aagctactga atttatagaa
   114121 agaatccaaa aaggtgaaaa tcttcctata ttaacaagtt gttgtcctgc atgggtaaac
   114181 ttcttagaac acaattatcc agacaagtta aacttagcat ctagctgtaa gtctcctcaa
   114241 ggtatgtttg gttctatagc taaaaactac tatgcaccta aaatattagg aatcaatcct
   114301 gaagaacttt atgttgtatc tgtaatgcct tgtgtggcta aaaaatatga agcttcaaga
   114361 gaagaattaa gtgaatctgg aatactagat gttgaccttt ctataactac tagagagtta
   114421 gctaaaatga taaaagaagc tgctatcgat ttacctaatc ttcaagacca agattttgat
   114481 aatcctctag gaaaatctac aggtgctgca tctatatttg gagcaagtgg tggagtttta
   114541 gaagctgccc tacgtacttc atatgagaag ataactaata agactttaga taatgtaaac
   114601 ttcactaatg ttagaggtct taaaggaatt agggaagcaa gtatagatgt tgatggaact
   114661 acagttaatg tgtgtattgt aaatacactt aaaaatgcta gaaagattat ggataaggtc
   114721 agaagtggag aatgtaaata ccatatcata gaagttatgg catgtcctgg tggatgtgtt
   114781 ggaggtgctg gtcaacctta tcaccatggt aatactgaaa tagttgatag acgtgcaaat
   114841 gcgttatatg aaatagatag aaataaggct attcgtaaat ctcatgagaa tcctgattta
   114901 caagctattt ataaagactt ctttggagaa ccaaatagtg atgtagccca taaatacctt
   114961 catactcatt actttgataa gagttgtgtc tatggagagt gtccacaaga atgtgcttgt
   115021 gaagaagcta agtagtcata acaaagtata aaatttattc ttaaaaaagg attgtcttaa
   115081 aatactttta cgtaatttaa gacaatcctt attaatttca caaattaaat tatatttcta
   115141 aatagactta ttctttaatt aacctatcta ttaattaaag aatacctgcc attctcataa
   115201 gttgttttgc atttgtagtt ttacatcttc catcttttat cttatagtca aaatgaattt
   115261 tatcgtctac atagtactct gagaaatgat agtttacaac ttcaacatct ccactacctg
   115321 aaaggtcaca tagctcaaag tcatgtgttg tcaccatact tataacccag ggttttgata
   115381 atttctttac tgcctcactt gctccaataa ttctatcagc agagttagtt cccttaaaaa
   115441 tttcatctac tagaaccaac attggcagtt cttttaaact atattgaatc attgatttta
   115501 ttctaagaat ctcagcatag aaagttgata ttccttgact tacatcatct tgtattctca
   115561 tagaagtaaa tatagccata caggtcgcat caaaactctt agcgcatact ggagcacctg
   115621 catatgccag cactaagttt acaccgatac ttcttaaaaa tgttgtcttt ccagacatat
   115681 ttgaacctgt gataatacaa gtctgagaat ttaattgtat cgaatttgct atgacacttt
   115741 tttctgctat taatgggtgg tatacctctt caactttcaa tcttggagta tcttcatatt
   115801 ttattactgg aaaacatgta ttttccttta catgagaaat aactgttaaa cttattagag
   115861 cttcaaattc tccaatagat tcaaaccaat ctctaatttg atttccatat atacctttcc
   115921 atcgctccaa agcttctgca caatgatagt tccacatcaa aacaccacag gcaattatat
   115981 atagtatctg attatacctt aggtttacag catttcctat tgaatttaat tgtttaacac
   116041 ctcttgaaac tccacttccc ttagaaagtt tatcttgtaa ttctttcaaa tatgcactct
   116101 caaacgtctc tttttctaaa acctcaaaca ttttttcata tacttgtata cttctactaa
   116161 atgaaaataa tggagaaaga gtttgcataa gtcttggata tccaaaacca ctaaacccta
   116221 actggattat aaaaagtaaa aaaacaggta aaacaggtaa aaatcctaac atacaaaata
   116281 taaaagataa gattgttgca gttggtagac cccaagtaaa aatatgcatc cattttggta
   116341 tatacacatt cttattttct ccatactcta taaacgattc tatactacta tctgaattat
   116401 ttttttgctc tttaccaatt atattactga gtatttgaat atgaatagaa aaatcatctt
   116461 ttgataaaag ttcttttata gccctctgtc tttctaagat tacattctca tctggatttt
   116521 cattccacaa atatttggct aaaaaatttt tcccataaga tgtattagct acacagatat
   116581 attgatacaa tgatgctctt ccaaataagt ctaaatcttt tgcttgcgaa ttttcatctt
   116641 ttaagtattc tttaccatct attttaaatt ccttccaacc atctccaaat ctcttaatat
   116701 acttatttaa tacttcgctc ttacttttaa aatatgtttc ttcttctttt actttactat
   116761 gaataactaa gagtgctata aatattatta ttgataaaac tccaacaaaa atacctacta
   116821 tatttttatt gtaaaatcca atagcaaacc ctgctatcac tatcaaaaaa gatattaatc
   116881 ttgctgtact tatgttattt gactttttac ttaagagcaa ttctttttca gtactacttt
   116941 ctaaaagttt actaaaatat tctattccca taaaaaattc caactttctt gttatataat
   117001 gaaactcaaa tataaaatta atctagtatt attataatct aacactgtac tttaaattat
   117061 ccttatataa tatatcttat taataaacat tatatatata caacttgatt ttaatttata
   117121 aggtgtagga cataatccta atcaatattt aattaaatga tgtgtagttc actattattc
   117181 agtactactt agtatcgatt aattttgata attttttagt aaattcttga gctgcatcgt
   117241 atcccattcc tctttgtcta aaattcattg ctgctacttc taatatcata gcagtatttc
   117301 ttccaggttt aacaggtaca actaatttct ctacattaac accaagtatt tcttcgtatt
   117361 ctttatccag tcctagtcta tcataatact tagtttcatc ccaagcttct aaatgaacta
   117421 ctaaatctat cattttagaa tttttgattg cccctactcc atataaactt ctaacatcta
   117481 ttattcctat tcctcttatc tcaagaaaat gtcttattag ttcaggtgac tgacccacaa
   117541 gcatactttc atctaatttt cttatttcta cagcatcatc tgcaactaat ctattacccc
   117601 tttgaatcag ttctaatgct gtttccgact ttcctatact actttcacct tttatcagta
   117661 cacctatacc ataaatatct actagcaccc cgtgaattgt tgtgtgtggt gctaacttat
   117721 tatccaaata gtttgacagt ctatttataa gtctagtggt atttctattt gtgctcaaaa
   117781 gtattctttt atatttttta gccttttcaa ttacatctgg cttgatttcc aagtctctag
   117841 aaattattaa cgctggtatt tcatatgaga aaaatctatc tagtacttct tctcgaatat
   117901 gactatccat taatccaaaa aaattatatt ctgtctttcc aactatttgt attctttcat
   117961 atgcaaaata atcaaaatat cctgcaaact gtaatcctgg tctatttata tcttgagagt
   118021 agacataata atctacatca tcaggcatgt atactacttt taacttcaac tcttttatta
   118081 tctctcttat tgatacttta ttgctagttt ccattaattt tcttcctttc taaaaaaatt
   118141 ataaacatta tctgcaatgc ttttattcat tccatctact tctaaaagtt cttccatagt
   118201 agcttttttt atagcctcta catctttaaa gtgatttaat aatgatttct ttcttttttc
   118261 acctattcct tgtatatcat ctaagataga ttttgtcaaa gctttatttc ttagacttct
   118321 atgatatgtt attgcataat tatgaacttc ttcttgtata ctagcaataa atctatataa
   118381 attagttgtt ttatctagtt ctatttcttt ttctttgcat atcaatcctt tagttctatg
   118441 cttatcatct ttgtacattc cccaaagagg tatatctaca tcattgagtt ctagtacttt
   118501 ttttactgca ctaacttgtc cttttccacc atccaacaat atcaagtcag gtaaatttcc
   118561 atgttttaat cttctatcta caatttcagc catagaatca taatcattag gtccaataac
   118621 tgtctttatt ttatatctcc tatattcctt cttatctttt ttagcattcg tatacactac
   118681 catagaacca atcgaatcta caccttgtat atttgatata tcataagcct ctattcttat
   118741 tggcaacttt tctagattta atatttgttt taattcttcc aatgctccaa tacttttttc
   118801 atattttctt ttattcatat cagaaaattt ttcaagatat tctacagcat ttttcctaac
   118861 catttcaact aagcttttct tctctccctt ttgaggaact cttattgtta ctttttgccc
   118921 ctttttagat gacagccatt cttctaatat agaactatct tctatctcat cttctataat
   118981 taattcttta ggtatatact cttgttcatt ataaaattgt tttacaaatg aacttaatat
   119041 agaagctctt ggactatcca ttacaccttc taatataaaa tgttccctac ctacaatctt
   119101 accatttctt ataaaaaata cctggacaca agcttcatta tgagctcttg ccattgcaac
   119161 cacatcttgg tttaagtcac ttacagtagc atctattttt tgtttctgta tcatctcttc
   119221 aaggctcttt atcttatccc tatatacagc agcctcttca aatctaaagt tcatagaact
   119281 ctcattcatt ttttccttta aaagttccat caatttttct tctttaccag ataaacacat
   119341 tataatctct tctatcattt ttccatactc ttctttagaa acatttcctg tacaaggtcc
   119401 taaacattta tttatgtgta gatttaaaca aggtcttgtc ttattcttta ttgctttatc
   119461 tatatctatt ttacagcttc ttattggata cgtactactt ataagctcca aggtatcatt
   119521 cacagcagtt atattggtat agggtccaaa atactttgcc ttatctttaa gaactcttct
   119581 aacttttaag attcttggat aatcttcatt cgtagttact tttatatatg gataagtttt
   119641 atcatctcta agcactacat tatactttgg tctgtatctt tttattaaat tacattcaag
   119701 tattaatgcc tctaactctg aatccgttat aatatactca aacttatata tattcttaac
   119761 catagatttt actttagatg tatggttttt tgaagattga aaatactgcc ttaccctatt
   119821 ttttagagat atggcttttc ccacatatat tatatggtcg tatttgtctt tcattaaata
   119881 tactccgggc tcagaaggta atttttttaa atgctcttgt atatcaaaca tctcgccctc
   119941 caaaacatta aattttatac taaaattata ccctaaaata tgaattttaa aaagttatac
   120001 aatttccagt gctttagaca agttaaagtc catattccct tctataattg atttgaaaac
   120061 aattttaacc atgaagagta atatggactt tactttgtat tactatttac aacttatatt
   120121 tgactaattt acttataaca aaacagttta tcgtatatct gctctaaaat ttttcacaat
   120181 ttatataact taagaaaaat atttctttaa gaattgacct gtataagaac catcaacttt
   120241 agatacttct tttggtgttc cagttgcaac tatagttcca cccttatctc cgccttctgg
   120301 tcctaagtct attacataat cacaagtctt tataacatct aaattatgtt ctatgactat
   120361 aattgtattt cctgtatctg ctagtctttg taatacttgg attagcttgt ctacatctgc
   120421 catatgaagt ccagtagtag gttcatctaa tatatacaaa gtctttcctg ttggtctttt
   120481 actaagttca gcagctaatt ttatacgttg cgcttctcct cctgataatt gagttgaagg
   120541 ctgtcctaat ttaatatatg aaagtcctac atccattaaa gtttctaatt ttctttttat
   120601 atttggtata ttttcgaaaa actcaacagc ttcttccaca ttcatatcta atatatcaga
   120661 tatagtttta tctttgtatt ttacttgcaa tgtttctcta ttgtatcttt cacctttaca
   120721 aatttcacaa ggaacatata catctggtaa gaaatgcatt tctattttta ttattccatc
   120781 acccttacaa gcttcacatc taccaccttt tacattaaaa ctaaatctac cttttttata
   120841 acctcttgct ttagcttcat tagtagatgc aaaaatatct cttataaaat caaatacacc
   120901 tgtataagta gcaggatttg aacgaggtgt tcttccaata ggactttggt ctatatttat
   120961 aactttatct atactttcaa ttccttttat ctccttatgc ttaccagctc tttgcttaag
   121021 tctattcact ttacttgcaa cacctttgta aagtatatcg tttattaatg tactttttcc
   121081 agaacctgaa acacctgtta tgcatgtaaa cttacctaat gggaacttta catcaatatt
   121141 tttcagatta ttttctgatg ctttaactat ttctataaaa cttccatttc cttctctagt
   121201 agtctcagga agcaatattt gttttttacc acttaaatat tgacccgtta ttgagttctc
   121261 attttcaatt atttcatcta aagtaccctg tgcaactatt tcaccaccat gtatacctgc
   121321 acctggacca atgtctataa cataatcagc ttctctcatt gtgtcttcat catgctctac
   121381 aacgattaag gtatttccta aatctgttag atgtctaaga gtagttataa gcctatcatt
   121441 atctctttgg tgaagcccta tacttggctc atcaagtaca tataaaactc caaccaatgc
   121501 agaacctatt tgagtagcta atcttatacg ttgcgcttct cctcctgata aagttccagc
   121561 ttttcttgat aaatttaaat aatcaagacc tacatctctt aagaacatag ctcttccttt
   121621 tatctctttt ataatctcat gagctataaa tctctgtttt tctgtaagat ttatattttc
   121681 cataaagtca atcaattcat ttacagataa gtttgtaact tccattatat tttttccatc
   121741 aactaaaaca gataaaactt cctttttaag tctcatccct ttacactttg gacatggtct
   121801 ctctgccatg tattcttcaa tcttatctct catgtaatct gaattagttt ctctatatct
   121861 tctctctaag tttactatta caccttcaaa gtatgattta taatttctag ttcctccaaa
   121921 ttttgactca taagtaaact ctacaattat attatcttta ccataaagta attcctccac
   121981 aaaatcatct ggtaaatctt taaacggtgt tgtcaaagat acattaaaat gctctgctaa
   122041 actttttatc attttactgt aataagtgtc atcattaaca cctgttgaac cccatgctgc
   122101 cactgcacct tgttttattg ataaatcttt gtttggtact actaattctg ggtcaacttc
   122161 tttactttcc ccaagaccat tacaaacatc acaagcacca aagggagcat taaatgaaaa
   122221 catccttgga gataattctt ctatgccaat tccatgttct gggcatgcaa atttagttga
   122281 aaaaagaatt tcttctccat ctattatttg ggctattaca agaccatcag atagcttaac
   122341 tgcagtttca attgaatctg ctagtcttga ttctattcca tctttaatta ctattctgtc
   122401 cactacaact tctatattat gtttttgatt tttatttaag attatatcat cactaacttc
   122461 atagttctca ccattaactc taactcttac aaatccttct tttttgatat tatcaaagac
   122521 ttttttatgt gtaccttttt gtcctctaac aattggtgaa agaatttgta atttcgttct
   122581 atctggaaaa tctagcattt tatcaactat ttcttgaata gtcatctgac ttattttttc
   122641 accacatgta gggcaataca catctcctac tcttgcaaat aatagtctca aataatcata
   122701 tatttctgtt actgttccaa ccgtagaacg tgggtttttt gaggtagtct tctggtcaat
   122761 tgagatagct ggtgataaac cctctatata ttctacattt ggcttttcca tctgacctaa
   122821 aaattgtctt gcataagcag atagactttc tacatatctt ctctgccctt ctgcatatat
   122881 tgtatcaaat gccaaagaag acttcccaga ccctgacaaa cctgtaaaaa caataaattt
   122941 atctcttggt aattctaaat ctatattttt taaattatgt tcttttgctc ctcttattat
   123001 aattttatct tccataatgt tgtttttacc tttctatttt tccaattttt cttctaattg
   123061 tttcacttta tctctaagtt ctgctgctct ttcaaattgt aagttttgag cagcttccat
   123121 catctctgat tttaatttat ctatattagc tcttatttcg tctttatcat ctgtatcaga
   123181 tattccatat acaacttctt cctctgcaac cttagtagct tctatactat ctcttatatt
   123241 tttctgtata gttttaggaa ttatattgtg ctcttcatta tataaatttt gtatatctct
   123301 tcttctcttt gtttcatcaa tagcattttg cattgagtca gttatcctgt ctgcatacat
   123361 aattactctt ccattttcat ttctagctgc acgtccaata gtctgtatta aagctgtttc
   123421 ggaacgtaag aaaccttctt tgtctgcatc taaaattgct ataagtgaaa cttctggtat
   123481 atccaatcct tctctaagta agtttattcc tacaaggaca tcaaacttcc ctaatcttaa
   123541 atctcttatt atttctgttc tttctaatgt aactatatct gagtgtaaat atttaacttt
   123601 tatccctatt tctttaagat agttagtcaa gtcctcactc atttttttag ttaaagtggt
   123661 tataagcact ctttcatttt tttctatagt tttagttatt tctcctacca aatcatctat
   123721 ttgattattt ataggtctta cttctacaat tgggtctaaa aggccagttg gtcttattat
   123781 ctgttctgct attgtctctg agtgttgaat ttcataaggt cctggtgtag cacttacaaa
   123841 caacatttga tttatatttc cttcaaattc ttgaaaattt aatggtctat tgtcaagtgc
   123901 agaaggtaat ctaaaaccat tctctataag tgatgttttt ctagacctgt ctcctgcata
   123961 catacctctt acttgtggta tagtgacatg tgcctcatct acaattatca aataatcatc
   124021 tgggaagaaa tccattaaag tatatggtct ttctccttct gaccttcctg taatatgtct
   124081 agaatagttc tctatcccct gacaaaatcc tatttccttt aacatttcta tatcatactt
   124141 agttctttgt tcaattcttt gtgcttctaa tagcctatca ttttccttga aaaatttaat
   124201 ttgttcttga agctcgtttt ctatttctac aattgccttt tcaattcttt ctggcgttgt
   124261 tacatagtga gatgctggga atataacaac atgatttcta gtaccaacaa tcttccctgt
   124321 tacataatca atttctgtta ttctatctac ctcatcacca aaaaattcta ttcttattgc
   124381 tttttcatca ttactagctg ggaatatttc tagtatatct cctctaactc taaaggtacc
   124441 tcgtgtaaag tttatgtcat ttctttcgta ttgtatctct attaaccttt ttattacatc
   124501 atctctgtct ctttgcatac ctggtcttat agataacata agttctttat agtcttttgg
   124561 gtcaccaagt ccatatatac aagatacaga tgatattatt atagtatctc ttctctctaa
   124621 aatagatgct gtagcagaat gtcgaagttt atctatttca tcatttatgc ttgcatcttt
   124681 ttctatataa gtgtcactgt gagctacata tgcttctggt tgataataat catagtaact
   124741 tacaaagtat tcaactgcat tgtctgggaa aaattcttta aactcactgt aaagttgtgc
   124801 tgctagagtt ttattatgag ccattattag ggtaggtttc ttaacttgtt gaatgatatt
   124861 tgccattgtg aatgtttttc ctgaacccgt tacacctaat aatgtcgaaa atttctcatt
   124921 tctatttata gaatccacta ttgatttaat agcttctggt tggtcacctg taggtttgaa
   124981 gtctgatttt attttaaaat ccatagtatc actccttttt tcgaacatta gttcctgaca
   125041 tgtattatta tatcatacct ttataaaatt gtttaagtta ttttaaatat tttacccatt
   125101 taaattttac ttaaatctaa aacataaaaa aagacttcta tctttgcaat agaagtctat
   125161 aattcatgga aaataaatac tttattcaac ttacataata aaatcaaatg cttctttttc
   125221 aactccatct aattttaaat caaacatttt taatatagtt gctgcatgtg ctctcaggtc
   125281 tccttcttct ataaccacac cacctttaat atttggtcca aaagctataa atggaggtct
   125341 attaccttta gtaggtaaat gaccatgtgt cgcaacagca aacttgtaat cttttatatc
   125401 tgaatctttt ataatacttc cttcgaaatc atttccaaat gaaattcctt caagaccttc
   125461 aatcaccatt tcaaaatcac cttcaagacc aaggttagat gcttcctctt tggtaaaaat
   125521 attctctatg aataattctt ctttaaattc ttcaagcagt tctcttaatt ctgttaacct
   125581 atctaagtta tttactatta tttgagctga tattccagaa gaatttacat aggcatcaaa
   125641 atccttaact tctccatttt caacttttat aaatccattt gatttaagca agacatttgg
   125701 atttataact ttatcaactc taagatgacc atggtcccca agtattataa aatttgtatc
   125761 tttgtatgta cctgcatcct ttgtagcctg aataatatct cctagccatt tatcattcat
   125821 ttttaatgct ttatctactt cgtcattaaa taagccataa ttatgtcgtg tatggtccaa
   125881 tgtagctaaa tgtattagca ttaaatctgg tttatattcc tttattatat ctactgaaca
   125941 gtttactcca aataaatcca tgttgggttc taatttccaa tcaatataat gacaatgtct
   126001 attgtaaata ccgtccatta taaccttact ggagcttcgt tcaaaagttt ctcttgggtc
   126061 atcttctcta ctaggagccc atatttctgc aatattataa tctatatttg gatttgctcc
   126121 cattacaggc cataatacac tagaggtagt tagattattt tcttttgcta catctataat
   126181 agtttttact tttatgtcct ttgaatacca gtaccagtct ttattttctt tatttgggtc
   126241 aaatttttca ttatgatata taccatgttt tttaggatat actcctgtaa ccatactagt
   126301 atgacacgga tatgtcagag tgggataaac acaatttata ttttttacta tggagcaatt
   126361 ttctagtata gatttaaagt ttggtagatt ttttacaaat tccaagtctt tttcaaataa
   126421 agaatctact gataatacta taacctttgt catttacatt acctcttcat ttatatatta
   126481 ttgaatactt ttaatcaact tacaagtcta tataattatt tatttgtttt atctattact
   126541 gcttgcattg cagaagttcc tttgcttact acatcttttg gatttgcatt taaatcagta
   126601 agcccctttt taatctcatc cattagctta tcagttgctt ccttgtatcc atttaacatt
   126661 ggaagtgcaa cagcatattg taattggtca gttgcaacct tatattgagg tttttcttta
   126721 tataatgttt gtaacttttc tgagtttgtt gcatcttcag ttgttggtaa gtatcctgtt
   126781 gatgaactaa actgaacgat tttatctgtt tgtgtcatcc attctataaa ttctgcactt
   126841 gcttcttttt ctttatctgt tccaccttca agcataacta gattagctcc acctgtagga
   126901 gttgcgtatt tttgattttt tggtaggaat gctgttgata tttcaaactt accttctgtt
   126961 tgttgcataa gtcctgctaa atctgctgtt gatgtaaata tcatacctac tttaccattt
   127021 acaaaatctt gttttgctac gtcccaggca ttataatctt ctccaggagg cattttcatt
   127081 attccagctt tcatcatatc ttgccagaat ttaactggtg cttgtcctgc ctcattatta
   127141 aatgctactt ttttaccatt agttatttct cctccacttt gcattaccat agcttcatag
   127201 aaccaaatat ctattggtgt ttcaaaacca taagtatctt ctgatttatt tgtcatttta
   127261 ctagcgtaat ccttaagctc ttcccatgat tttggacctg aagggtcaag acctgcttta
   127321 gttgccatat ctctatttat gtataatatt ggtgtacttc tattaaatgg cataccaaca
   127381 aacttatcct cataatatga atttgttaaa agaccagaaa agaatctttc ttgatatgtt
   127441 ttatcaaaat atttactcat atctactaaa gcacctgctg atgcgaatgt acctgtttga
   127501 gttatttcta ataatgttac atctggttgg tctttagatg ttaaggctgc ctgtagtttt
   127561 gttgcatttt catagtaatc tttctgtttt aacatattta cttgtacatc cttatgttca
   127621 ctattaaatt ggtcaaccat tttttgagca gtttctccat tagttccacc taaaggagcc
   127681 cagaaatcta tcttcgtaat attgctatca gtcttttctc ctttagatgc atttgcatca
   127741 ttagaatttg aacacccaac taaagaacct aataataatg ttattgctaa tcctgttgct
   127801 aattttcttt taagcttcat tttcatcctc caaatttagt ctttaatttt ttattttatt
   127861 cctgaataca taaaagcttc ttttactttt ttattcgcaa atatataaac aagaattatt
   127921 ggtaaaatta gaattatatt tcctgccatt attacattcc atgcagtaat tccttctgaa
   127981 gatttaagga gcgcaactcc tattggtaaa gttcttattg catctgtatt tgtcattact
   128041 aagggccaga aataattatt ccaatggtat ataaaattaa ataatataaa tgttattact
   128101 gctggttttg ccataggaac cattattcta aacattattt ttaagtcaga agcattatct
   128161 agtttagctg cttcaatagt ttcatctgaa atctgcataa aattctgtct aagcagaaat
   128221 atcccaaatg aagatgtcat aaatggaatt ataagtggaa tataagtatt tataaatcca
   128281 aacttactca tcatcatata gactggtaga aaagttactt gtggtggaat cataagtcct
   128341 acaagcaaaa gcccaaataa cattttttca cctttaaatt taatcttaga aaatgcatat
   128401 gctgctggaa ccataactaa aaattgtaaa attaaaacac ttcctgttac aaatacactg
   128461 tttagtaaat atctaaaaaa tggacctgaa tgccatgctg tactataatt ttctaacact
   128521 atatcatttg gtataatagt aggtggtaat tgcatcattt cttgtggatt tttaaaggat
   128581 gtcgatagca tccatataaa agggaatata aatattgcag ataaaagtaa tagaattaat
   128641 atttccattg attttgatgc tatttttttt atatcaactt tgtctttttt gataggttgt
   128701 ataatatcca ttgtctcctc cttttggata aatcttataa tatctacttt ttctttattg
   128761 ataatgaact ttctttgata agagtctaaa gttagcatat gtagcaatca taactatagc
   128821 taacaaaaac atactcgctg cactcgcttg ccctatgtca tagtatataa atccagactc
   128881 atatatataa taagataaca tgttagttga acccactggc ccaccttgtg tcattatact
   128941 tatctcatca aatacttgaa aagatgcagt tgttgttgtt atcataagaa aaaatattgt
   129001 tggtgataat agcggcaatg tcactttaaa gaaattcgtt attttgtttg cattatctaa
   129061 tttagatgct tcatatatat agtttggtat ggatttaaga cctgataata ctattaagat
   129121 attgtatcca agagtcttcc atattcctat tagaattagt gacattaaag ctgaactttc
   129181 acttgaaagc cactttgatg ttggtaaatg taatgtcgat agtatccagt ttaaaaagcc
   129241 atattgtggc tccataatcc aaagccacaa tacagctaca gatactagtg aaattacatg
   129301 tggtgtaaag attatacttt gcgttaaatt gtgtattata gaatttttat ttagccaaac
   129361 agcaagtact atggctagtg atatagatat agtcaccata aaaaaagtat aaattgcagt
   129421 gttcgttata gtttgtataa actctggatt ctttaaaagt tctgtataat tgtttaagcc
   129481 tacattttca aaggttgaac taagaagact accagatttg aagcttagag atatcgtctt
   129541 aattattgga tagactataa acaataaagt tcctataata gcaggtgtta tatataaata
   129601 tgctttatta aattgctttt tcataaatat ctcctttaat tttagaatac atacttttac
   129661 atacttttac atcttctatt ctttctccat ttttatcaaa ataatataaa tctttttcta
   129721 atacacttat tcttaaagtt cttccaatat caaatatatc attttccgtt ttgactctta
   129781 tttctctatt aagaacagat aaacaatata tagtttcatt tcccaacact tctttagtca
   129841 caacttttcc aaataggcta aatacatcat cattttttcc atctatgttt atactctcta
   129901 gtgttgcttt ttctggtctg aatccaaatt taatatcatt ttttatatct agtatgttca
   129961 tacaaggact ccctataaat tgagctacaa ataaattctt aggattttga tatatcttct
   130021 ttggagaacc tatttgcatt atctttcctt tgttcattat aactatctta tctgccattg
   130081 acattgcctc aacctggtca tgagttacat aaacaaatgt agattttagt ttttgatgta
   130141 attgtattaa ttctgttctc atttgatttc ttaatttagc atctaaattt gacaatggtt
   130201 catccattaa aaataccttt ggatttttaa ccatagctct agcaagtgcc actctttgtc
   130261 tttgacctcc agataagttg cctggtttca catttaaata ttctctcaat cctactacat
   130321 caataacttc tgttataagt ttttctcttt tttctttttc tacttttttg tttttaagac
   130381 caaattctat gttttctcta acagtcatat gtggatataa tgcataattt tgaaatacca
   130441 tagctatatc ccttttacta gcatccgttt ttgtaacgtc attttcttca atttttaact
   130501 tgcctgaagt tatatcttca agacctgcaa tcattcttaa tgtagtagat ttaccacatc
   130561 cacttggacc taccaatact gtaaaagaac catcttctat agtaagattt aaattttcta
   130621 taactgtatt ttttttatta taagattttg ttacattttc tagtcttata tctgccattt
   130681 ttatcctccc aaaatattta atttaattct acgatttact tatagattaa taatactctt
   130741 aatttgtaaa ggatatatta agacaaagtg aatatatagt aaacttatta aaataaaggt
   130801 taaattataa acattttttg ttaaatatac tgaagttaag atgatataca gcttatgtta
   130861 gctataattt tctatatttt tcatattcat ggtttgctat cacaatgtga ttttaattta
   130921 tgaagagtca tataaaacta tttatttttt atataatttg gtttgaaaat aaaaaagacc
   130981 tctatggggg atagaggtct ttaagtgggg gagattgagt aatttatttt tgctatatta
   131041 agttttacaa ttatattatg tcccaaattt acaaggttta aacataaaaa ataaaacttt
   131101 tttaattttt ataaatttac ccaaaaaaaa ttacgtggct acgtcctact ctcccaggca
   131161 gtttcccacc aagtaccatc agcgctagag agcttaactt ctgtgttcgg aatgggaaca
   131221 ggtgtatcct ctctgctatt gtaaccacat aatctttatg cttaatattt ctattaagtt
   131281 tttaataagt ttatagaacc tagtaatact agtttcttta gagtta
//
LOCUS       DAMJYN010000002       126771 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.002, whole genome shotgun sequence.
ACCESSION   DAMJYN010000002 DAMJYN010000000
VERSION     DAMJYN010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 126771)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 126771)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..126771
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.002"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(26..1375)
                     /locus_tag="PC466_000118"
     CDS             complement(26..1375)
                     /locus_tag="PC466_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDF2767554.1"
                     /translation="MEKAKKLGLFSMILLGINSIIGSGIFLLPGKVYSLAGQNSMFIY
                     IFATLLVLSILLCFAEVGSMFDKNGGAYLYSKKAFGDFIGFEVGTMSWFIRIISWSTL
                     AVGFATALGSFWPESATEYKGCIAAILVTLLSINSLFGIKSTKIMNNVITIAKLVPLI
                     VFVIVGIFFIKFVNIVPSGNVVNSSMGPAIILVFYAFTGFESFIVASGEMENPKKNLP
                     IALITTIFICAIIYILIQIVCMGILGDRLFENSIPIADASSVFLGNYGKVFISVATLI
                     SIFGINIGSSIVTPKCGSSLAEEGSLPAFIGKTNKYGAPYVAIIISLICCIPLVLTGS
                     FEQLAVMSVIARFAQYIPTCLSVIVLRKRTDVKASFKIPFGPVIPMVAILGSLWLLQQ
                     AWAEDISKPITQNRVLIGLGAMLLIAPLYIFMKKNKEIEHKNKSEDSKLYISREKIQ"
     gene            complement(1412..2632)
                     /locus_tag="PC466_000119"
     CDS             complement(1412..2632)
                     /locus_tag="PC466_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2767555.1"
                     /translation="MQQALKLKYQTKELGKDFVIESCNSIKPWLINIRRELHKIPELA
                     LEENLTKQKVISYLKEIGIDYMEFTKHNGIMAYILKESADKTICIRADMDALPIEEEN
                     NIPYKSIHSGKMHACGHDAHTTMLLGACKVLHSIKDKLNVNVKFLFQPAEEGFGGAKF
                     LVEDGCLENPKADYIFGLHVMPHIETGLIETKYDTLNASVDTIKISIKGKRAHGAYPE
                     NGIDAIVTASQIVTSLQTIISRNLEPNNAAVLTIGKIYGGDAHNVICEDVKLEGTLRT
                     LNSKTRNFMIDKIAKIVGDTASAFGCVGTLHVSDENYPAVINEKELVDTVISSTKELL
                     GEEKFILRPNPSLGGEDFSFYTEHCKGAFFHLGCKNEEKGLISPLHTSSFNIDEDCLP
                     IGVMMHVMNTLYFN"
     gene            complement(3001..5013)
                     /locus_tag="PC466_000120"
     CDS             complement(3001..5013)
                     /locus_tag="PC466_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2767556.1"
                     /translation="MKKSVALVNDSRKDLIDFLENNLKLVFGDSININRYFINEINDN
                     DIINDDVILVMSVERLDKIINNILDKKKVIVVRRTFREDKIYNLLSLPQGTNALIVND
                     SDETTLETISLFYKIGVTNIRPIPYMNDNNYKNIKIAITPGVPEKVPSFISDIFDLGH
                     RYIDISTFIEIINLLQIDSKEIQSNLVKYSEEIISLDTGIKDKYKELFLKIEELDTIL
                     NLSKDGILFTSKDGEINTYNSKVKDILDINEDIYGKYIDDIFVDSLKVLLSEKEILDK
                     VVVFNKKYINVNKKNIYNRDEKMGTYYSLQEITYIKKLEQNLTKKLREKGQIAKYTFK
                     DIKTNSPKMFECIDLAKKVSKSDLSILIRGESGTGKELIAQSIHNNSNRKNQPFIAVN
                     CAAVPENLLESQLFGYDKGTFTGGLKDGKQGLFELANNGTIFLDEIGDMPLELQTKLL
                     RVLQEKQIMPVGSHNVINIDVRIISATNKNLEQMIDNSQFREDLYYRLNTIPINIPPL
                     RERKEDILIIMEDLINKKLVITPEAKKLIQNYMWKGNIRELQNVTSYLNIMCEDIVLE
                     KDLPPNLRSSDNKNTSLKLKYSKNDILNILEILILNKESDVGIGRGLILKALLDKNLQ
                     ITEGKIKKIFEYLKKEELIICSSGRYGSKITQKGEDFYNKLKYKGL"
     gene            5484..6134
                     /locus_tag="PC466_000121"
     CDS             5484..6134
                     /locus_tag="PC466_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic nucleotide-binding domain-containing
                     protein"
                     /protein_id="HDF2767557.1"
                     /translation="MKAEKTSIYPIIKNNLNKISIVEYKKGQRFVASDKDLQEVFFII
                     EGVALVECTTRGGNKFLVDIVPENEFIGKISYIYEHNLKCDIFAKTNIKLFRFEKNVF
                     EEFYLKPDFIALFHRKCTRRIYELYKTRMVRELFSCTEVIAYCISNKQENNVCNIKAI
                     RNFSEIYSISRKSRYHSLLKLTEKEIVKKMGNTYEILNYDELHKLAFEVKEFLEDE"
     gene            complement(6274..7650)
                     /locus_tag="PC466_000122"
     CDS             complement(6274..7650)
                     /locus_tag="PC466_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF2767558.1"
                     /translation="MQELFSLKDENKRFYKILLSLCIPIIIQNLISTSVNVIDTIMIS
                     SLGETSVASVGVANQFFFLFNMSLSGITGGAGVFISQFYGKKDVSNIRKVTGLTCVLA
                     IVLSFVFVIPALLTPKPIIHIFSYDSEVVKLCIDYFSIAVFSYPLIAVSTVFSTGSRG
                     VRNPKLGMICSAFALVTNVILNYGFIFGNFGLPALGVKGAALATVIARICELILMITY
                     VYLYKKDYILKFGLKNLKAIDKIFIKSFSSKSFPIFVNDSVWAIGTVLYSVAYARAGT
                     SAIAASQIATSTGNFFIMTAVCIASGASIMLGNELGADHIKRAIEYAKKFSILVFSAG
                     LILGIILILNIPLLLKMFSVSDSLASDITKIFFIMGILMALKSFNTLVIIGILRSGGD
                     TKYALFLELGCMWLASIPLTFIAAFKGAPIFVLVLLTYSEEVVKFIFGVPRALSKKWA
                     INIVKEID"
     gene            complement(7666..9579)
                     /locus_tag="PC466_000123"
     CDS             complement(7666..9579)
                     /locus_tag="PC466_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HDF2767559.1"
                     /translation="MIVLSCNNLNKSFGIDSILENISFTVNEGDKIGIIGVNGTGKTT
                     LFKIISGIYGYDSGDIYTSKDCEIGYLEQNTNFYSDNTILEEVLEVFKNLIEMESYLR
                     ELEVKISEESTKTNSPIIEKIMDEYSHKLELFSDLNGYGYKSEAKGVLKGLGFSDNDM
                     DKPISILSGGEKTRVLLGKLLLKKPTLLLLDEPTNHLDSEAIEWLEVFLKQYKGTVML
                     ISHDRYFLDQSVNRIFEVHNKKLKVYNGNYSKFVELSKIEKELELKKFEDQQKEIKKQ
                     EESIERLKAYGREKHLKRARSKEKALDKVDVLDKPEAYRKKARIQFTPSVQSGNDVLQ
                     IRDVSMGYGERILFKDLDLDIYRGEKVALIGANGVGKSTLFKIITNELQPLSGNIKFG
                     TNVHVSYFHQEQKTLNLDNTIIDEIWENNTHLTQTTLRNMLGAFLFVDEEVFKKISTL
                     SGGERARVAILKLILSNANLLLLDEPTNHLDIDSKEVLEEALTNYDGTIFTISHDRYF
                     LNTVVDKILVLDENGITEYLGNYDYYIDKKRQIQEMSIIEEKEEKTRTQIKDEKRKER
                     EQREIEKKNRIKRQNIEKEIEKLEIEIEKLDILLCQEEVYSNPDKAKEVSQEKINLEN
                     NLASLYDEWEEFM"
     gene            9715..10347
                     /locus_tag="PC466_000124"
     CDS             9715..10347
                     /locus_tag="PC466_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HDF2767560.1"
                     /translation="MLGNKNISMAVIRRLPKYHRYLGDLLDRDIQRISSKELSDIIGF
                     TASQIRQDLNNFGGFGQQGYGYNVEALHTEIGKILGLDRPYNAVLVGAGNLGQAIANY
                     AGFRKAGFEIKALFDANPRMIGLKIREFEVLDSDTLEDFIKNNNIDIAVLCIPKNGAQ
                     EVINRVVKAGIKGVWNFAPLDLEVPKGVIVENVNLTESLFTLSYLMKEGK"
     gene            10486..11025
                     /locus_tag="PC466_000125"
     CDS             10486..11025
                     /locus_tag="PC466_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraR/DksA C4-type zinc finger protein"
                     /protein_id="HDF2767561.1"
                     /translation="MVFVEELWKKAIEFHGHECPGLAIGFKAALAARKYLGCKQSGDE
                     EIVCISENDACGIDGIQVVLSCTMGKGNLLLRMTGKSVYHFFNRENGKSIRIYVKSKP
                     FQMDREGYKKYLLESDFEEIFEITDTKLRLPEKARIFKSLKCEVCGEFASEQYIRIEE
                     GKKVCLDCFNKYERFYEEY"
     gene            complement(11201..11371)
                     /locus_tag="PC466_000126"
     CDS             complement(11201..11371)
                     /locus_tag="PC466_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004619190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDF2767562.1"
                     /translation="MAYKITDACISCGACEAECPVSCISAGDDAYVIDAGSCIDCGSC
                     AGACPVDAPQPE"
     gene            11656..12723
                     /locus_tag="PC466_000127"
     CDS             11656..12723
                     /locus_tag="PC466_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HDF2767563.1"
                     /translation="MKNKLVYICIMSLLLFVVGCSNNPNKESTIKKDSKNNQSQVKEE
                     KREPVKKDITISFAGDVTMGNYKGSSYYGSFDHEFKRQGEDYNYFLKNVKPVFEKDDL
                     TVVNLEGPLTTASNAKEKKFAFKGKPGYVNILKSGSIEAVSIANNHSEDYFEEGMKDT
                     QFILDENKINYFGLGKDAVVDVKGIKVGLLGYNGLSTEYNEKNLKQMEDDIKSLKKKS
                     DVVVVYFHWGIELDYYPDKKQKDFAHYAIDKGADLVMGSHPHVIQGIEKYKNKYIAYS
                     LGNFCFGGNKNPSDTDSYIYQQTFTFSDNKLTSIKEPNIIPTSITSSSSRNNYQPKVL
                     DGSEKDRVLNKLEKISKDLNK"
     gene            12893..14794
                     /gene="cooS"
                     /locus_tag="PC466_000128"
     CDS             12893..14794
                     /gene="cooS"
                     /locus_tag="PC466_000128"
                     /EC_number="1.2.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic carbon-monoxide dehydrogenase
                     catalytic subunit"
                     /protein_id="HDF2767564.1"
                     /translation="MACNTCKMCESADKKLESFVASKDVETAFHRTEDQKVKCGFGLQ
                     GVCCRLCSNGPCRVTPKSPRGICGADADTIVARNFLRAVASGAACYLHVVENTAKNLK
                     NVGITKGVVKGEKTLNQLAEMFGIESDEKYDKCIKVADKVINDLYKSRDDKMELVEKI
                     AYAPRVKKWKELGIMPGGAKSEVFDAIVKSSTNLNSDPVDMLVNCLNLGISTGLYGLT
                     LTNLLNDVMLGEPVIRMAPVGFNVIDPDYINIMITGHQHSTFANFQDRLKDEDVIKLA
                     QSVGAKGFKLVGCTCVGQDLQLRGEHYQEVFAGHAGNNFTSEAVLSTGAIDIVLSEFN
                     CTIPGLEPIADKYKVKMVCLDDVAKKANAEYIGLDRSKLDELSNTLIEKALESYKERR
                     GSIEIDIPKDHGFEQSLTGVSEKNLKAFLGDSWKPLINLIAEGKIKGVAAVVGCSNMT
                     AGGHDVNTVELTKELIKKDIIVLSAGCSTGGLENVGLMSPGAEELAGENLKEVCKTLG
                     IPPVLNFGPCLAIGRLEIVATELAAELGIDLPQLPLVLSAPQWLEEQALADGAFGLAL
                     GLPLHLALPPFITGGKLVTEVLTEKLKDLTGGHVIVNPDPKSSANQLEEIIIDRRKNL
                     GLKDVECNA"
     gene            14787..15260
                     /locus_tag="PC466_000129"
     CDS             14787..15260
                     /locus_tag="PC466_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HDF2767565.1"
                     /translation="MHRIFINKDLCTGCKSCVLACMLKHNKDYDMYTLDLENIDNDSR
                     GHIELDSKHNNPVPILCRHCDEPECVLACMSGAMHKDSESGIVSYDEEKCGSCYMCVM
                     SCPYGLLKPDDRSKQNILKCDLCKDEEYPRCVANCPSGAIELQKEENDELCSVRG"
     gene            15235..16461
                     /locus_tag="PC466_000130"
     CDS             15235..16461
                     /locus_tag="PC466_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDF2767566.1"
                     /translation="MNYVVLGASAAGINAVKTLRELDKDSNIVVISKDENVYSRCMLH
                     HVISEHRTLKQINFVDEDFMEQNNVKWIAGKTVKGIDINKKVVQTEDITVNYDKLLIA
                     TGASSAIPPIKNLRDGNFVYSVRNIDDIYKIKEKAQNSKNVVIIGAGLVGIDALVGLF
                     KYEQLNISVAFMEKYILDRQLDEYTASVYENKFKEKGVKFYPSASIQEIVLDNSKNVT
                     GVAFSNGEVLDADMVIVATGVKPNADFLDGTGIEYDRGIIIDDMCQTTQKDIYAAGDV
                     VGKNAIWPLAVKQGIVAAYNMVGKDKKIEDEFAFKNSMNFMDIPTISIGMNTPVDDSY
                     KVLTRHGINDYKKFVFKDNVIYGAVIQGDISYVGVLTYLIKNKVEIYDLENRIFDVCY
                     ADFFNIKENGEFCYSV"
     gene            complement(16600..17787)
                     /locus_tag="PC466_000131"
     CDS             complement(16600..17787)
                     /locus_tag="PC466_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDF2767567.1"
                     /translation="MNITKNFLKDYLEKFGETPFLVRLKDEEEFLIGEGSPQFKVIVN
                     NDISKSELLKSTSLALGEAYINRDIEVEGDLFLTLNLLLKQIDKFNIDNSAVKHLLHS
                     SNSMRHQKKEIHAHYDIGNDFYSLWLDKTLSYSCAYFRNDNDTLYDAQVNKVHHILTK
                     LNLEEGMSLLDIGCGWGFLLIEAAKKYKIHGVGITLSEEQFKEFNARIKEENLQDYLE
                     VRLMDYRELKKSDLMFDRVVSVGMLEHVGRENYELFIKNVNAVLKDGGLFLLHYISGL
                     QESYGDPWIKKYIFPGGVIPSLREMIHICSDYKYHTIDVESLRLHYVKTLLYWQKSFS
                     ENLPKIKEMFDDKFIRMWDLYLCSCAAAFNTGIIDIHQILFTKGIKNDLPLTREYMYN
                     CSK"
     gene            18060..18884
                     /locus_tag="PC466_000132"
     CDS             18060..18884
                     /locus_tag="PC466_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HDF2767568.1"
                     /translation="MEVYALVGSSGTGKSFKALEFAYENDIEYIIDDGILIYKNKVLA
                     GISAKQANTTIEAVKRAIFYNLEHRQEVREAIKKENIRKILIIGTSKKMVNQIVERLS
                     IGRVCKFINIQDISTKYEIEIAKQARKEGNHVIPVPAVEIKSMASGLSINSLKRLFRK
                     GNNRNMVVLEKTIIRPTFSYIGKFYISADVIKQIIEYEVYNFGSIDRINKINIENCNN
                     FMNIFVSININDLETIKKIEDIQQTIKKSIEKMTLVNVQKIDINIHKIKKINFLQC"
     gene            19013..20278
                     /gene="gluD"
                     /locus_tag="PC466_000133"
     CDS             19013..20278
                     /gene="gluD"
                     /locus_tag="PC466_000133"
                     /EC_number="1.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-specific glutamate dehydrogenase"
                     /protein_id="HDF2767569.1"
                     /translation="MSGKDVNVFEMAQSQVKNACDKLGMEPAVYELLKEPMRVIEVSI
                     PVKMDDGSIKTFKGFRSQHNDAVGPTKGGIRFHQNVSRDEVKALSIWMTFKCSVTGIP
                     YGGGKGGIIVDPSTLSQGELERLSRGYIDGIYKLIGEKVDVPAPDVNTNGQIMSWMVD
                     EYNKLTGQSSIGVITGKPVEFGGSLGRTAATGFGVAVTAREAAAKLGIDMKKAKIAVQ
                     GIGNVGSYTVLNCEKLGGTVVAMAEWCKSEGSYAIYNENGLDGQAMLDYMKEHGNLLN
                     FPGAKRISLEEFWASDVDIVIPAALENSITKEVAESIKAKLVCEAANGPTTPEADEVF
                     AERGIVLTPDILTNAGGVTVSYFEWVQNLYGYYWSEEEVEQKEEIAMVKAFESIWKIK
                     EEYNVTMREAAYMHSIKKVAEAMKLRGWY"
     gene            20471..21127
                     /locus_tag="PC466_000134"
     CDS             20471..21127
                     /locus_tag="PC466_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HDF2767570.1"
                     /translation="MYFLPPHDYKLEELDWIFGHELMYFKSKDLHLKYLVLFLKIVYW
                     FNPFIYIMEKYMDLDCELYCDERVLKNCTVQQKQEYALTIVNSMKRGINFSNKFVTGL
                     NKQSDIRKRVMNMFSEKHKNGILMALIISLFSSITFFKFDSTSLIEENDFLERSRYAF
                     EGRQEDMFVTIDSTYADAPIKLRKEHEENCRVNGIVPKDSDSIEIIPRFYKDCMDLKK
                     "
     gene            21458..22591
                     /locus_tag="PC466_000135"
     CDS             21458..22591
                     /locus_tag="PC466_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M56"
                     /protein_id="HDF2767571.1"
                     /translation="MSNFILNGIFRTVIVSSLSILLILIFKKNVFKRFSKKFNYYIWM
                     IVVIKLFLPFTYYTFTINILRSKKHININNINLEGFNNVSTISNNIILYTWIITVVVY
                     LIYTIFKYIKLKNLINDLSYDVDDREIVNLYKNILEEFNITKDIKLKYSYEVETPAFF
                     NSCVLLPPHEYKLKELDWIFRHELMHFKSRDLYLKYVILFLKTVYWFNPFIYIMDKHI
                     DLDCELYCDERVLKNRNSEEKKDYALTILNAMRKGSNTSNKFIAGLHKQSDIKKRVMN
                     MFNEKYKNGILMALTLCLLSSITFLKVNSTSIVNLNVLPKGFEDLRTVSSIRFSVIGF
                     TYADAPKNMREEYKINCESLGLIPKDSDKIEVGVEYYDSLLND"
     gene            23518..24540
                     /locus_tag="PC466_000136"
     CDS             23518..24540
                     /locus_tag="PC466_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HDF2767572.1"
                     /translation="MKKKILIPVFASVMALSVSSIVNADEVNDSSQNKDDKTNTELNL
                     GEYKEVKYKVAKIKDGVAIKIREEGQVQNIAYSGDEFTVLGTQGEWVKVKVEDGEGWL
                     ATRYVDISEGVGYTNADKVNLRKDKSESSEVIEELEKGSSLLVLEDNGDWLKVKDGET
                     EGYVKSSYISDKAPVIEEPQVNPSIDQNVDSTNNNQQNNANTNQQNNNSNVPTANSNA
                     VQAVLNLAYSKQGCPYVWGAEGPNTFDCSGFTQYVYRNAVGKNIPRTSKAQSKYGQTV
                     SKANLQPGDLVFFTTNGSGSVSHVGIYVGGGNMIHSPSTGKTVSVTSINSSYYTARFV
                     TAKRIL"
     gene            24836..25756
                     /gene="pyrB"
                     /locus_tag="PC466_000137"
     CDS             24836..25756
                     /gene="pyrB"
                     /locus_tag="PC466_000137"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase"
                     /protein_id="HDF2767573.1"
                     /translation="MLKSRNLIQPEDFSIEEIDEILELAQKIIDNPSKYSRICEGKLL
                     ATLFYEPSTRTRLSFESAMNRLGGRVVGFSEPNSSSASKGETLGDTMRIVSGYVDIIA
                     MRHPQSGAASEAARYTEVPFINAGDGKNQHPTQTLTDLLTIKSLKGTLESHTIGLCGD
                     LKYGRTVHSLVKAMARYKNTKFVFIAPEELKMPDYIKEAIKGHAYYETNNLDDVIGSL
                     DVLYMTRVQQERFEDKSEYERLKNYYILNKAKLEKASKDMLVMHPLPRVNEIDIDVDS
                     DDRAVYFKQAKYGMYVRMALIIKLLGINED"
     gene            25795..26487
                     /locus_tag="PC466_000138"
     CDS             25795..26487
                     /locus_tag="PC466_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HDF2767574.1"
                     /translation="MYKILENIYIGEDMYRMKVKGNFEGKMGQFYMLRAWDTYPVLSR
                     PISIHDIDEEGITFLYKVVGEGTQILSNLKVNDNIKLEGPYGNGYAKVDGKVALVGGG
                     IGVAPLYLVAKNIKNCDAYLGFREDVILEDEYKQVCNKVYTTVGNTFVTDIIDVEKYD
                     YILTCGPTPMMEKLVKMVEGTKTRIMVSLENHMACGVGACLVCTCKTNGGNKKTCKDG
                     PVFWGEDVIFNG"
     gene            26480..27382
                     /locus_tag="PC466_000139"
     CDS             26480..27382
                     /locus_tag="PC466_000139"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HDF2767575.1"
                     /translation="MGNLSVKFGSVEFKNPVIMASGTFGFGKEYNEIYDIQKLGGISS
                     KGLTLNKKPGNNGMRVHETPSGMMNSVGLENPGVQGFIDYELPFFSKLDLVRIANVGG
                     GTLEDYLLGVQMLNDKPIDIIELNISCPNVKAGGMAFGIKNEVAREVVREVRNITKLP
                     LVIKLSPNAEDIVGMAKVCEEEGADGVSLVNTFKAMAIDIKNRRPVFENVYAGLSGPA
                     IKPIALRMVHEVCKNVNIPVMGMGGITKATDAIEFIMAGATCIQVGTANFMNPRIGIE
                     IIDGINEFMDREGIKSLDEIRGII"
     gene            27467..28051
                     /locus_tag="PC466_000140"
     CDS             27467..28051
                     /locus_tag="PC466_000140"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HDF2767576.1"
                     /translation="MSKVDVVDILKKSDALLEGHFLLSSGKHSNRYVQCAKVLRFPEY
                     AAEVLSTVVEQIKDLDIDLVVGPAMGGVIVSYELGRQLGKEAVFTERKDNTMELRRGF
                     EVKKGAKIIIAEDVVTTGKSTMETKRVLEALGGEVVGVACIADRTNHDIGMPIYSAIK
                     LDIQVYESDECPLCKEGKLPVVKPGSREFKELGM"
     gene            28266..29192
                     /locus_tag="PC466_000141"
     CDS             28266..29192
                     /locus_tag="PC466_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketopantoate reductase family protein"
                     /protein_id="HDF2767577.1"
                     /translation="MKNQLNENHKKVVFFGVGAVGATFAEQFFNSKYDFKILCDNERK
                     KRYLEEGFIINGKRYDFNYVTKDEYKQEADFIIIGLKYNNLKENIKELDGLVGKNTVI
                     MSLLNGVDSEEIIGERFGIGKMVYSYVTNIDAKKINNNIIHTTNGIIVFGNKDNSEDR
                     KTNIITEVFDDVNIEYILSKDIQRDMWWKYMVNIGVNQTSAILGAPYGVFQSSEHLRE
                     LAKSAMREVVAIAQAKDISLTEDDVENSLHRILEHSKEGRTSMLQDVEAHRPTEVDMF
                     SKNICKLGKKYSIPTPINQTLFYMIKVIESRF"
     gene            complement(29244..30134)
                     /locus_tag="PC466_000142"
     CDS             complement(29244..30134)
                     /locus_tag="PC466_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDF2767578.1"
                     /translation="MFEELKTFVAVVEYKNFTKAGEYLNLSQPSVSKHIKNLENYFKV
                     VLINRSIKQKTIFITESGQILYKRAKEILNLLNITYHDVSQVSDAITGHLKIGASLTI
                     GEYILPNFLALFSQKYPDIYVEVFIKNTSIVSSHVKDYILDIGLIEGTCSSPSFIQEY
                     FFEDKMVLALPYNSHLLKDFSFDKLQDQKWIVREDGSGTRDYLDMFLSVKEIIPKSMM
                     VFGSNYAVKESVRNNLGITIVSNLVTSLPVLNNELSVIELGSSYNRHFSYIFPKDITL
                     SKAATIFIEELKIFSNLNSI"
     gene            30322..31353
                     /locus_tag="PC466_000143"
     CDS             30322..31353
                     /locus_tag="PC466_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HDF2767579.1"
                     /translation="MLKKKSSLTLKTIREILPGLFISVLVGYISIFISILIPKVGAAS
                     ISIFLGMFVGNLFLNQKVFQKGYKFSETDLLSYSIVLLGATLSVSTLIDLKVSGILFI
                     ILQMTITIIAALYIGKKLGFEENFRFLMASGNAVCGSSAIGAIVPVVNATDKEKGIAV
                     TIVNVTGIFLMFLLPIISQFLYSHELVKTSAMIGGTLQSIGQVVASGAIVGENVKDLA
                     TIFKIVRVIFLVVVVLVFGHMKNQSNREILEEEKDEIKKKKVTIPWYVIGFFITCALF
                     SMNIIPKEVSVLCKEISNKLEIIALAAIGLKVNVKDLVKQGKEVSLYGLFVGTVQVVS
                     AVVLIKIFI"
     gene            31647..32522
                     /locus_tag="PC466_000144"
     CDS             31647..32522
                     /locus_tag="PC466_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxoguanine DNA glycosylase"
                     /protein_id="HDF2767580.1"
                     /translation="MNVYEKGNGVILEGVTDFDPVHIFECGQCFRWHKQEDGSYTGVA
                     RGRILNVKKENDKIYLNNTNLKEFNSIWYNYFDLGTDYTEIKNKLKNMDEYLNKATEF
                     GWGIRILRQDGWEMLISFIISSNNRIPMIQRAIENLSRKFGKYIGEYEGNEYYAFPTP
                     EELNKASQEEIRACQTGFRDKYIKSTTQAVIENNDEVSEYTNLSTEDCRKELLKFNGV
                     GPKVCDCIALFGMQKYDSFPVDVWVKRVMQEFYIDEDMSLPKMRTYGIDKFKEMSGFA
                     QQYLFYYARELGIGK"
     gene            32540..34030
                     /gene="cls"
                     /locus_tag="PC466_000145"
     CDS             32540..34030
                     /gene="cls"
                     /locus_tag="PC466_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HDF2767581.1"
                     /translation="MGVIGTIFLFYLIISYLAGAIISVIILLENRDPAKTMSWLLMFI
                     IFPGVGLMIYAISGRNIRKRKLFKTQKLANNIKEKKLFDTLEKITEIVELEKESIKQN
                     KLLRDEEDGSYRKRVINMLLKTGMFPFTKNNKVDVFVDGNEKFKRLIEDIREAKDHIH
                     LEYFIIKDSEIGRVLKEELIKKAKEGIKIRILYDDVGCWRFWFNRKFFREMREVGIEI
                     AAFLPTKFPIIGGKLNYRNHRKIVVIDGIIGYTGGINIGDEYLGKNDKFGYWRDTHIR
                     IKGISVYMLQMTFLIDWYYTTKEVLVTKNYFPSVGNVGESMIQVVASGPDSDWEDIHY
                     AYFSAICQARKNVYIETPYFIPDESLLKAIKSAALSGVDVRIIFPKIADHKIVNIASY
                     SYFEEILRAGGKVYLYNKGFIHSKVVIIDDKIASAGTANMDLRSFMLNFEVNAFIYDE
                     EVIRVMTDDFFEDLSHCEELNLEVFKNRNIIQKIKESVARLFSPIL"
     gene            34223..34507
                     /locus_tag="PC466_000146"
     CDS             34223..34507
                     /locus_tag="PC466_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012062101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HDF2767582.1"
                     /translation="MKIRPLADRVVIKKVEAEEKTASGIVLPGAAKEQPQIAEVVEVG
                     PGGIVEGKEIKMELTVGDKVIFQKYSGTEVKIEGQEYTILRQSDVLAVIE"
     gene            34540..36168
                     /gene="groL"
                     /locus_tag="PC466_000147"
     CDS             34540..36168
                     /gene="groL"
                     /locus_tag="PC466_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729227.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HDF2767583.1"
                     /translation="MAKEIKFSEETRRALEAGVNKLADTVKVTLGPKGRNVILDKKFG
                     SPLITNDGVTIAKEIELEDRFENMGAQLVKEVATKTNDVAGDGTTTATVLAQAIIREG
                     LKNVTAGANPILLRKGIQKAVIVAVEELKNQSRIVETQEAISQVASISAGDEEVGKLI
                     AEAMEIVGKDGVITVEESQTMNTELDAVEGMQFDRGFVSAYMVTDVDKMEAVLNDPYI
                     LITDKKISNIQELLPVLEQIVQQGKKLLIIAEDVEGEALSTLVVNKLRGTFDVVAVKA
                     PGFGDRRKEMLQDIAILTGAQVISEELGYDLKEADLSMLGRASSVKVTKESTTIVDGS
                     GDKKAIEDRVTQIKHQVEQTTSDFDREKLMERLAKLAGGVAVVKVGAATEVELKERKL
                     RIEDALNATRAAVEEGIVAGGGTAFVSVIPAIGTLIESLEGEVKLGAQIVKKALEEPL
                     RQIAINAGLEGAVIVQNVVNSEAETGFDALNEKYVNMIEAGIVDPTKVSRSALQNAAS
                     IASTFLTTEAAVADLPEKEDAGMPGMGGGMPGMM"
     gene            36430..37170
                     /gene="larB"
                     /locus_tag="PC466_000148"
     CDS             36430..37170
                     /gene="larB"
                     /locus_tag="PC466_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel pincer cofactor biosynthesis protein
                     LarB"
                     /protein_id="HDF2767584.1"
                     /translation="MDLRKLLEEVKNENIDIDFALEKLKDLPYEDLGYANIDHHRELR
                     NGYPEVIYCEGKSDEHILGIIDKMNQKSSNILGTRCRKETFLKIKEIYNHAEYEEASK
                     ILKIQNHDIENIGKGKIVIATGGTSDIPVADEAYHTAKFLGNDVDRIYDVGVAGIHRL
                     LNKRHKIDSARVIVAVAGMEGALASVIGGLVDVPVIAVPTSVGYGANFGGLAALLAML
                     NSCASGISVVNIDNGFGAGYLASMINKL"
     gene            37254..37988
                     /gene="larC"
                     /locus_tag="PC466_000149"
     CDS             37254..37988
                     /gene="larC"
                     /locus_tag="PC466_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel pincer cofactor biosynthesis protein
                     LarC"
                     /protein_id="HDF2767585.1"
                     /translation="MSEKILYFDIISGISGDMTLASLLNLGVPKEIFLEEIHKLRMSD
                     EFNINISSKTENGIVGTKVEVITKEKHTHRNLVDIFEVIDKSTLNENVKSKAKKIFMV
                     IGEAEAKVHGTTIDKIHFHEVGAIDSIVDIVGASILVDLLCVDKVCASTVSVGSGFVK
                     CEHGIIPIPAPATIEILKGVPIKLNNVNGECTTPTGAAIIKVLCDEFVDELEFSPKQI
                     GYGIGHKKFEVPNILRTVLGEKKKKN"
     gene            38018..38437
                     /locus_tag="PC466_000150"
     CDS             38018..38437
                     /locus_tag="PC466_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF111 family protein"
                     /protein_id="HDF2767586.1"
                     /translation="MSSEIYSYLYEKILDEKALDIYTESIYMKKNRPATKVSILCNES
                     DLEKFIKILLLETSTFGVRYNAYNREILERKFVKLDTKYGVVTVKLGYYKGKLVKVTP
                     EYNECKTIAKNEDIPIKKVFADINFRIKEEFSENLLT"
     regulatory      38497..38598
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            38819..40354
                     /gene="guaA"
                     /locus_tag="PC466_000151"
     CDS             38819..40354
                     /gene="guaA"
                     /locus_tag="PC466_000151"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HDF2767587.1"
                     /translation="MKHELVLVIDFGGQYNQLIARRVRENNVYCEILPCTASIERIKE
                     KNPKGIIFTGGPNSAYLEDSPTISKEIFELGVPILGICYGIQIMSHVLGGVVRKGNKQ
                     EKEYGKTSITYGKSSLFEGITTNSVWMSHTDLIEKVPEGFTIVANTNDCPVAAMENVE
                     RNLYGVQFHPEVEHCLEGDKILTNFLYNICKVKGDWTTDSFIEDKIKELKEKIGDKKA
                     LCALSGGVDSSVAAVLIHKAIGDNLTCIFVDHGLLRKNEGNDVERIFREKFDINLIRV
                     NAEDRFLSKLKGVSEPEAKRKIIGEEFIRVFEEESNKLGKMDFLVQGTIYPDVIESGH
                     GNAATIKSHHNVGGIPEDVDFQEIVEPLRELFKDEVRKIGLELGIEEGLIFRHPFPGP
                     GLGIRVIGDVTKEKCDILREADAVYMDELRKAGLYREIWQAFATLPDVKTVGVMGDER
                     TYAYLVGLRAVTSSDGMTSDWYKMPYDVLERISNRIINEVDGVNRVVYDITSKPPGTI
                     EWE"
     gene            40893..42323
                     /locus_tag="PC466_000152"
     CDS             40893..42323
                     /locus_tag="PC466_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HDF2767588.1"
                     /translation="MILNQIFIEDGGIMRNKIIIGITFSLVLLMSGCASKQTAEINVL
                     ATTDLHGVIPYELTSYVKEERKKDKNLTLVDAGDFFDSGEVFGSSMDSYFSARYKDGD
                     NNTESYIETPISKDMKEVGYDVAVLGNHEFISNNKFYLDNMISDFEKQKINILSANTY
                     KKNGDSYTKPYIIKNINTPEGNVKLGILGLTIKEVGERKQWKDGKLVDSKSLELKDQE
                     GYNGELYMNDLVEDAKKWVGIMEKEKPDIIVAVAHTGEKPKKPRNPGNRIQDLAQQVD
                     GIDAIVAGHNHVQIEQHDYKNKSGENVIVTEPGKHGEYISKINFKLEKNNDKWNIVDK
                     SSKLIKFEKNQESDKFGEFISSINKVSKDKKEIRLSEVKTPEWDKIYVFKSGTSADDI
                     YKTIGYKWRNISSPKGDDMVQIVVMNNNKPVSYIYGEAEVMPINIKCDESEYKNNVVT
                     IYPNKNDKFKIEKGKQEYSINLKHIQ"
     gene            complement(42471..43346)
                     /locus_tag="PC466_000153"
     CDS             complement(42471..43346)
                     /locus_tag="PC466_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDF2767589.1"
                     /translation="MINIRYLEILEAIEQTGTFTGAAKKLHITQSAVSHAIAELEQQA
                     ETSLFDRLPRGVCLTRCGISLLDEARSILTACRNLDKKISRLEECTPINIVSSITIAS
                     FLLPPILSRLKNSFPSLKVNVRVESANSAMDILKSGEADICFWEGIEPQGAFRTILLG
                     SYKLCVACAPTFPLSEQTLSLRQLCTFPLLLREQGSAIRDTLDSVLSLSNQKAYPVWE
                     SVNSFALIKAAEAGLGITILPENLLLDSLLHKKLRLIELDEIDMENKMLAILHKDKNI
                     TQPLEIILDNISNVL"
     gene            43466..44029
                     /locus_tag="PC466_000154"
     CDS             43466..44029
                     /locus_tag="PC466_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HDF2767590.1"
                     /translation="MNQSRKIYFWLLIINLFISTFTFGGGYVVVPMIRRYFVNQKQFF
                     TEDDLMSMAAVAQSTPGAIAINLSALAGYRVAGTLGVVISCTAAIIPPLVILGLVSAF
                     YTTFISNAIVTAVLKGMQAGVAALIVDLIIDMCSMILKQRSLFLSTMIPIAFFANFVM
                     SINVIFILSVCCFVCVMQVFYKKRENK"
     gene            44026..44592
                     /locus_tag="PC466_000155"
     CDS             44026..44592
                     /locus_tag="PC466_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HDF2767591.1"
                     /translation="MNTIWNLFFIFLKIGLFSIGGGYAIIPLIQEKVVNQTGWISEKM
                     FTDIITISQMTPGPLAVNTSTFVGLQIGGFWGAVAATLGCVLCGVVISLFLYNFFQKH
                     QNSTYIFEILNGLKSASLGLIISAAATIIILALFGTNKVYFNSIFEMLNWTALIIFFV
                     ILLIVRKWKINPIVIIIISGILGIFFYL"
     gene            complement(44721..44957)
                     /locus_tag="PC466_000156"
     CDS             complement(44721..44957)
                     /locus_tag="PC466_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2767592.1"
                     /translation="MLECFIAEDSKIKDGVNIPTLVFKTLHDRYFKTQYFDSYYNSLK
                     CKKKLVEINNVHNSYYIDSEKFCQEAYDWFVENQ"
     gene            complement(45267..48695)
                     /gene="uvrA"
                     /locus_tag="PC466_000157"
     CDS             complement(45267..48695)
                     /gene="uvrA"
                     /locus_tag="PC466_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HDF2767593.1"
                     /translation="MKINNYKNQSIITNPKKFENKYQDLPKTPIELLKVVQSLVIHGD
                     QGKLYGISFNKQQSDEELLRTIPQMLKRIFEINSNPLTIPRNPKQRLVGMCRDYSLLL
                     VSLLRYRGFEARMRAGFANYFENELTYEDHWLVEYYDTLTKRWIRIDAQIDDIQKNYF
                     QINFDTHDVGKTDGFLTGSEAWIRCRQGHAHPDDFGYNKNWKGWHSVKGNLLHDFNNM
                     IGLELLPWDLWTELSSKKYNQLTRAEKNLLDEMAEILSSGNIKIEDLNLLIEKLPEDY
                     LKSIFSQLKILGISEIKELGNPLELEKKFKFAKAINKSIKNSLCHNKSSIYLKGGRQN
                     NLKDVEVTIPKNQITVITGVSGSGKSSLAFDTIYEEGKRRYFENLGNGAKLSEQLQKP
                     EFDLLQGLTPTIAIEQKKGSQNPRSTVGTLTSIWDYLRMLFVSIGKSYCPYCKTPLEK
                     KNNTKNYCPHCQTIFSKINTSTFNANSHTGACHDCNGLGFTYQVNPQLIVKDPTISIL
                     DGATYYFGKLRGKKPNGNWMVGELYAIAKDKNIDLDIPWNELPRDFIDAILYGTDDKI
                     YEFSFESKGRESKIRRPASGAINHIQRLFRESSSENNTLHQYMNKIPCNTCGGELLCI
                     EARFTTIKGYRFPELTKMTIEQLWNWLCELPNQLQKNELSLVNDILTELKIRVSYLLK
                     VGLSYISTDRTAPTLSGGELQRVRLSSQLGSELVGLTYILDEPSIGLHPRDHNLIIKM
                     IEELRDKGNTVIVVEHDKDTILSADYIIDVGPNAGTKGGFIIAEGTTQEIIKNPNSIT
                     GKYLSTYNKISSQNKIIPSKWLSLKGCHANNLKNIDVEIPLNCMCSITGVSGSGKSSL
                     VFHSLLPALEEKLKQKSIPNKNYTALTGFDAIDDFILMDQTPIGKSSRSTPATYINIF
                     DEIRSLFTETPQAKQKLLDESYFSFNSKKGQCPNCQGLGKTKIILQYMADQWVTCNEC
                     QGKRYQKEILSIQYKGKTIADILDMEVAEAKTFFSDCSDIYRKLSLLDEVGLGYLKLG
                     QNTLGLSGGESQRIKLAKELGTKTKKRMLYILDEPTTGLHFKDIENLLITFRKLVNEQ
                     HSLLIIEHNTEVIRASDWIIDIGPDSGINGGEIVASGTPDEIKINPNSITGHFI"
     gene            49014..51248
                     /locus_tag="PC466_000158"
     CDS             49014..51248
                     /locus_tag="PC466_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDF2767594.1"
                     /translation="MKLSRYKKNSLVLSIILCSLIISILVITVFNTVKLHNISNKQSK
                     NYLNDVSTQIVMNVDSKIKFILSDLRIMADFIKQYEGDSRYEYLSKRKTSYKYYDVGI
                     IDLEGKAEFLSGKKFDLKNTASYKKGIEGKEYSEVIESMGFVLYSVPIFNDNHEVSSI
                     LIGVSNKESMDEILNIDSFNGEGTIEIINSQGKTLFIGKNNELIKDLSYKYKDSADEP
                     WAQKMLNDFKNDKSGNITITSSKGVQCLLTYHPITRGLNDWHFLLIVPEDVVLGELNK
                     LNSFTIIMTFITTCIIGIITLILYIIRRKYVNQIENIAYLDSITNGINSTKFSMLVKP
                     LISESPDSTYMMIAMNIKDFKLINDCFGSEKGNMTLKHLYNILYKNIDENEEFVCRHD
                     ADLFYLLIKNRPVLEALELLYKIEADTNYFNKNRENPYFLRLSVGIYTIENHNEDLIT
                     IQDHANTARKSFNKTHQSDFSFYSDIERKRLISEKEISNLMEKALENKEFFMCLQPKI
                     DIKSGKISGAESLVRWKNSEKGIIYPSNFIPLFEKSGFICKLDLYILEETCKLISKWI
                     KEGKEVLRISVNVSRQHLNDKLFLEKYKHICNKYNVPTCLIDLELTESIFLENPEAID
                     IIEDIHSNGFKCSIDDFGFGYSSLGILKDFKVDIIKLDRSFFVSKNNIDRGKVVIKSI
                     IELSKRLGMKVTAEGIEELEQVEFLKNVGCDYIQGYVFSKPLLISDFENFAYENNKIK
                     NIHY"
     gene            51504..53534
                     /locus_tag="PC466_000159"
     CDS             51504..53534
                     /locus_tag="PC466_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2767595.1"
                     /translation="MISGRMLLIMNFLKGKNKTSYKDISKQLSIEERKVRYDINNLNI
                     VLRSLNKSVIQKMNKGVLIIPDDFQVVCINNNEYVFSLTERVSIMKIISMFKIDNLNL
                     EKLSKEFQVSRSSIKNDLNVLSSELERNQITITYDKSFKISGEEDLIYKQRLNILKSY
                     SYLFGKEKSDLSVFEKYLVNVIEKIFKGIYLIDIYNWSMNLLLQMGWTLNDESFTWYV
                     SNIFLFTWYIHSDEKHPLESASLSEPCFENKFDQEFETIIQKKLTKEQIFLLKSFVFF
                     TNKYASLNEDMDLISTEIIVQDLIYNMSEILEISFKEDMILYKGLLNHIAPLIERIKQ
                     NIQIYEELLHVIPDKYQYVLEATKVSIQKNRVLSQIKNENEIILLAIHFLGSIHRNER
                     NNYKNILLVCGFGYGVIAMLKDSLVNDYQINIVESIPSYKLQDYKEWESIDFIITTSK
                     IVIDLPKTIIEINPFLQEEDYLKFEEKGIKRKNVLTNYMSIKKRLDFLEEDAQKRVLS
                     IICQELGYSDERILFRQLNLSDLIGIDTIRIIDEDMKWEDAVKISSNILANCDFVSAQ
                     YAENIIDILKNVGFYAVKDNEFALLHGNDSSLVKVSSISLLICKEAVSFGDKKVKIIF
                     CLASRDKKEQIPAIINLTKMVYKTNFIAMLESAKTKEEAEVLIHKYEKEVTV"
     gene            53531..53983
                     /locus_tag="PC466_000160"
     CDS             53531..53983
                     /locus_tag="PC466_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2767596.1"
                     /translation="MNKLVNVKCSFKIHANSKEEAIVSLVDVVSKEGYLIDKNQFLED
                     VLKREETLSTYIGHGIGLPHSQSVGVKNSCITIGKLDIPIEWTEEGEKVDLIFLISVT
                     KDNENNLHLKILSKLARLLMHESFRNQIRCSDEQTVYNLIKEKIEEED"
     gene            53985..55040
                     /locus_tag="PC466_000161"
     CDS             53985..55040
                     /locus_tag="PC466_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit EIIC"
                     /protein_id="HDF2767597.1"
                     /translation="MRILKFLQKHLMTATSYMIPFVVAGGILFALSVTLSGQAAVPET
                     GWLAKLNQIGAAGLALFIPILGGYIAFSMADKPGLAPGMIGAYLAKEVNAGFIGGIIA
                     GFIAGFVVLQLKKIKLAPTMRTLGSIFIYPLIGTLITGGIIVFLIGEPIASFMTWMTN
                     WLNGMSGVSKIPLGGILGGMIASDMGGPINKVAATFAQTQVDTLPYLMGGVGVAICIP
                     PIGLGLATLLFPKKFSKEERDSGKASLLMGCVGITEGAIPFATSDPVRVIPCIMAGSI
                     IGNIMAFLLGCLNHAPWGGLIVLPVVDNRLGYIASVLTGAVVVAVLMKLVKKDVKEDE
                     EIEEDLDESIELIFEEL"
     gene            55107..55415
                     /locus_tag="PC466_000162"
     CDS             55107..55415
                     /locus_tag="PC466_000162"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose-like transporter subunit IIB"
                     /protein_id="HDF2767598.1"
                     /translation="MKIVAVTSCPSGVAHTYMSAESLELSAKKFGIEIKVETQGSSGI
                     DNELSLKDIDEATCVILTNDVEIRNMERFKGKKVVRMSVSEIIKKSDALIKKIKDTFQ
                     "
     gene            55519..56784
                     /locus_tag="PC466_000163"
     CDS             55519..56784
                     /locus_tag="PC466_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II D-tagatose-bisphosphate aldolase,
                     non-catalytic subunit"
                     /protein_id="HDF2767599.1"
                     /translation="MKKLPIKTVVQRLLDLQEEGKSATLLGIGPMSPNLLQASFELAK
                     DDDFPLMFIASRNQVDADELGGGYVNGWNQETFTKDIKKIADKVGFDGLYYLCRDHGG
                     PWQRDKERNDHLSVDEAMELGKKSYLADIEAGFDLLMIDPTKDPFEIGKVIPLDVVLE
                     RTVELIEYCENERKRLNLPDIGYEVGTEETNGGLTSTETYETFITRLKVELDNRGLPM
                     PTFIVGQTGTLTRKTEQVGTFNFRNAYDLAQMAKKYGVGLKEHNGDYLDDVTLLEHIP
                     SQIIATNVAPQYGTEETRAYLKLAEVECKLEKEGLVDKTSNIRHVLLVNAIECGRWRK
                     WVVGEQKNLTTEEIFKNEVLSNEILDIAGHYTFNNDDVKKEIEVLYDNLSKNNIDGQR
                     FVVDHIKRPLRDYAECYNLKGVTTRILNK"
     gene            56872..57588
                     /locus_tag="PC466_000164"
     CDS             56872..57588
                     /locus_tag="PC466_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HDF2767600.1"
                     /translation="MINLIFDVDDTLYNQLTPFYTAYNKVFSSIKDISIEDLYMSSRK
                     YSDEVFHMTENGEMPIKEMHIYRIMKAFEELGNSITEKDAQSFQDEYIYQQSQITLIP
                     EVERILNFSKERNINLGIITNGPSNHQRMKLKQLNIENWVDKSNIFISSEVGFSKPDT
                     NIFRVAENVMNLDRENTYYVGDSYRNDVLGAKKAGWKSIWLNHRGHEVEELFYKPDFV
                     ILEHKDLISLFIKICSYKNM"
     gene            complement(57783..58076)
                     /locus_tag="PC466_000165"
     CDS             complement(57783..58076)
                     /locus_tag="PC466_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat protein"
                     /protein_id="HDF2767601.1"
                     /translation="MRNMIENLIKNNTYIDDKVIMLSMLSSAKASANMYLNSALTSST
                     PELRAIYSASLTQMVEGHTALTELSINKGWVKPYDKPIQQLTCSYKESQNVID"
     gene            complement(58082..58297)
                     /locus_tag="PC466_000166"
     CDS             complement(58082..58297)
                     /locus_tag="PC466_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2767602.1"
                     /translation="MRTLSETEKISLAAVIKMESDGLLMQRAINMLISDEDLKRQSES
                     SILATEGRIKAIQQFIVENEILISEEV"
     gene            complement(58842..59354)
                     /locus_tag="PC466_000167"
     CDS             complement(58842..59354)
                     /locus_tag="PC466_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDF2767603.1"
                     /translation="MLEVIKNRRSIRTYIDKNIEEDKITEILKSAMQAPSSKNAQPWE
                     FIIVDDKELLKELSKSQHRAKHIEFAPLCIVVLGNRDKFLKPGKWIQDLGACTQNLLL
                     EVTNQGLAACWAGVFPKNKVVNKVKQILDLPVKLVPYALISIGYSEEKNEFIDRFDEN
                     KIHRNVYKNR"
     gene            59804..60280
                     /gene="purE"
                     /locus_tag="PC466_000168"
     CDS             59804..60280
                     /gene="purE"
                     /locus_tag="PC466_000168"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HDF2767604.1"
                     /translation="MKVAVVMGSKSDYPKLEEGIKLLEKYGIEVVARALSAHRTPEQL
                     SIFLKEIEDDTDVIIAAAGKAAHLPGVIASQTLIPVIGLPIKSSTMDGLDSLLSIVQM
                     PKGIPVATVTIDLGLNAALLALQIMTLKYPKLKEDLKSYREEMAQKVLEDDKNLRG"
     gene            60286..60984
                     /locus_tag="PC466_000169"
     CDS             60286..60984
                     /locus_tag="PC466_000169"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HDF2767605.1"
                     /translation="MLLYEGKAKQVYSTDNENEYVVYYKDDATAFNGEKKAEISSKGI
                     LNNKISTIIFEMLKENNINTHFIKSLSDREMLVKKVEILPLEVIVRNIAAGSICKRVG
                     LEEGVVFDEPIFEISYKNDAYGDPMLNDDYAVAMKLATREELKFLREETLKINELLKA
                     FFLKLNLKLVDFKIEFGKDSEGNIILADEVSPDTCRLWDVNTNEKLDKDRFRKDLGDL
                     VEGYTEVLSRMNNK"
     gene            60996..62363
                     /gene="purF"
                     /locus_tag="PC466_000170"
     CDS             60996..62363
                     /gene="purF"
                     /locus_tag="PC466_000170"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HDF2767606.1"
                     /translation="MCGVLGIYSNKDVTKELYYSLYSMQHRGQESCGLALLDDGEIKY
                     KKDMGLVGDVFKENELSKLKGNIGIGHVRYSTAGGSHVSNCQPLVGSCRKRQLAIAHN
                     GNLVNANYLKDMLEEDGYMFQTNSDTEVILYILARYYKGDIVESLKVTMDYIKGAYAL
                     VIMSQEELVAVRDPHGFRPLVLGKKGDEYIFASENCAIDILGGEVIRDVEPGEIIVVK
                     DGELKSYFYSENYKPVKKSCIFEHIYFARNDATIDNVNAYEFRIKCGERLAQNETVKA
                     DMVVPVPDSGWPGAIGYANASGLKISEGLVKNRYVGRTFIKPTQEEREIAVKIKLNPL
                     STIIKGKSIILVDDSIVRGTTSKQLVKSLREAGAKEIHLRITSPPVAYSCYYGIDTPN
                     RSKLIASSNNVEEMREYIGCDSLKFLDIEGMLDATEHKSTFCKACFDGEYPVKKIDKE
                     ELLSC"
     gene            62357..63433
                     /locus_tag="PC466_000171"
     CDS             62357..63433
                     /locus_tag="PC466_000171"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HDF2767607.1"
                     /translation="MLTYKESGVDIDEGNRAVDLIKGKIKGTYDGNVVGDLGNFSGLY
                     SLKDFVGMKEPVLLASTDGVGTKLKIAQMMDKHDTVGIDLVAMCVNDLICQGAKPLFF
                     LDYIALGKLVPEHIEKIVGGIADGCKMSGCALIGGETAEMPGMYGEDDYDLAGFSVGI
                     ADKEKIVSGNNVKSGDVLVGISSSGVHSNGFSFIRKIFLETYNYKMEQYVEELGMTVG
                     EALLTPTKIYVKLALDVLAKHDIKAIAHITGGGLIENITRVIPKGLGLDINKKSWEKP
                     PIFKMIEGFNAVDERELHKSFNMGIGLVLIVDKENADDVVNFINNRENDNAAYVDKKY
                     SELLEDKAYIIGEVVDSHEGVELC"
     gene            63427..64020
                     /locus_tag="PC466_000172"
     CDS             63427..64020
                     /locus_tag="PC466_000172"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HDF2767608.1"
                     /translation="MLNIGVLISGGGTNLQAVIDGTESGEIKGQVKVVISSKQGAYGL
                     ERAKNHNIKAICETDEDKIIEILKENKIDLVVLAGYLKIISPKLVNEFRNKMINIHPS
                     LIPSFCGAGFYGEKVHQGVIDYGAKVTGATVHFVDEGADTGPIIMQDVVKVNQDDDAK
                     TLAKRVLEVEHRILKESISLFCENKLKLQGRRVFINE"
     gene            64013..65545
                     /gene="purH"
                     /locus_tag="PC466_000173"
     CDS             64013..65545
                     /gene="purH"
                     /locus_tag="PC466_000173"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HDF2767609.1"
                     /translation="MSKRALISVTDKTGVVEFAKELNKLDYEIISTGNTFKTLKENGV
                     NVMQVEDVTNFPEILDGRVKTLNPYIHGGILYKRDKESHVETVNEHKIHSIDLVAVNL
                     YDFEGTLKAGKSHDEIIENIDIGGPSMIRSAAKNYKDVIVVVDIKDYDSIIEKLKTDT
                     MTLEDRKKLSYKAFSTTGRYDALISSYFAGEVGDTYPDILNLTFQKEQTLRYGENPHQ
                     NGFLYSQSNAKNPILNYEQLGGKELSFNNLNDLHGCLEVMREFKDSEEVVSVAIKHAN
                     SCGVGLGKDAFEAYTKCYEADKVSIFGGIVGITSTIDKATAEKLNEIFLEIVVAYDFE
                     PEALEVLKQKKNLRILKLAKIEDSLQPYEMKYLDGKLLIQDRNNILAEKSENVTKAKP
                     TDAQLKDMEFGMRVVKNMKSNAIAIVKNGQTLALGCGQTSRIWALKNALENNKDKDFT
                     GAVLASDAFFPFDDCVTLAHEYGISAVVQPGGSIKDKDSIEACDKYDMVMVFTGIRHF
                     KH"
     gene            65556..66806
                     /gene="purD"
                     /locus_tag="PC466_000174"
     CDS             65556..66806
                     /gene="purD"
                     /locus_tag="PC466_000174"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HDF2767610.1"
                     /translation="MKILVVGGGGREHAICWKLSKEKNVEKVYCAPGNAGITNVAECV
                     NIGDTNIEELLKFAKENEIGLTIVGPEVPLVMGIVDEFEKEGLRVFGPNKKCAQLEGS
                     KAFSKEFMIKHNIPTAKYKEYTNLEEAISEIDSFGYPVVIKADGLAAGKGVVIPENRE
                     DAIATLKEMMSDKKFGAAGDKIVIEEFLKGIETSILAFVDNDTIVPMASAKDHKKVNN
                     YEQGPNTGGMGTFSPSEIYTEELANKVKETVLEKTLEGFKKDGLNFKGILFVGLMITE
                     DGEKVLEYNVRFGDPETQSVLFRLETDLHEIMETILDNKLKDIEINYSDDEAVCVMLT
                     SGGYPDSYEKGKIITGLENLDDDIVVFHSGTKMLDGNLVTNGGRVIGITAKSTTVKDA
                     AEKVYENIKKINFEGMHYRTDIGR"
     gene            66831..70637
                     /locus_tag="PC466_000175"
     CDS             66831..70637
                     /locus_tag="PC466_000175"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HDF2767611.1"
                     /translation="MLNTENKDSMVRRVLVEKREGFDLEAKALKKDLVESLHIDNIEN
                     LRILNRYDVEGISEEVYENAAKTIFSEPNLDVVYYEEIPKLNDERVFAIEFLPGQYDQ
                     RGDWAAQCVQIVNQGIRPAINTAKVYILSGKITDEEFSKIKDYCINPVDSREASLEKP
                     ETLKMETEIPTTVEVLDGFIDLDENGLRTFVSEKGLAMTLGDLQHVQKYFKDTEKRNP
                     TITEIKVLDTYWSDHCRHTTFMTEIENVKIEDGKFNDIVKEAYQMYLNSRDNVYVNRH
                     KDICLMDIATVAVKELKKNGKLNDLDESEEINACSINVDVEVDGKMEKYLVMFKNETH
                     NHPTEIEPFGGAATCLGGAIRDPLSGRSYVYQAMRVTGSADPRTTLEDTLPGKLMQRK
                     ITTEAAHGYSSYGNQIGLTTGQVAEVYDENFVAKRMEIGAVIAAVPKENVVRERPEAG
                     DVIVLLGGKTGRDGCGGATGSSKEHSEESILTCSAEVQKGDAPNERKIQRFFRNKEVA
                     QMIKRCNDFGAGGVCVAIGEIADSLDINLDLVPKKYDGLDGTELAISESQERMAVAIK
                     KENKDKFIQLAVEENLEATHVATVTDTGYLRMFWNGKAIVDINREFLDTNGVKQTTDV
                     HVTKVDEENTFFSSNEIVKDVKCASMKDKFTKVLSDLNVCSQKGLVEMFDNTIGGNTV
                     LMPFGGKYQATPTQGMVAKIPVLGGETNTSTIMTYGYNPKVGKWSPFHGALYAVVESV
                     CKLVAIGGNYSTTRLTFQEYFEKLGNNPEKWGKPFSALLGAFYAQSKFEIPAIGGKDS
                     MSGTFKDIEVPPTLVSFAVDTVDAKKVVSPEFKKADSKVVMLCVNKAENDVVDFEELK
                     RNLDKVRELIHGNKVLSTYALGFAGVGEAISKMAFGNKIGFKFSEEAEKTFTDDKLFE
                     ASYGNIVLELANDDLCMLEGYNYVVLGSTTKEASIFIKGEELALDELYKAHCSTLEPI
                     FPTKTEEVKSKIETISYISQGEAKKSSLSIATPRVFIPAFPGTNCEYDSARAFERVGA
                     NANIRVFKNLTYKDIEDSIDTIVNEIKSSQIIMLPGGFSAGDEPDGSGKFIATVFRNP
                     RVQEAINEFLTQKDGLMLGICNGFQVLIKLGLVPYGEIRVPSESAPTLTYNNIGRHQA
                     KIARTRISSNKSPWLAQTNVGDIHNIAISHGEGKFVASEDVMRELIANGQVATQYVDF
                     NNEATYDIEFNPNGSFYAVEGITSADGRVFGKMGHSERIGEEVFKNIIGEKDQKIFES
                     GVKYFR"
     gene            70843..71715
                     /gene="rfbD"
                     /locus_tag="PC466_000176"
     CDS             70843..71715
                     /gene="rfbD"
                     /locus_tag="PC466_000176"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HDF2767612.1"
                     /translation="MKILITGSNGQLGKELVSQLEAINQSINQPKYVILATTRNDLDI
                     SNQTNIDNFILHNKPDVIVNCAAYTKVDACEDNIEIAYKINALGVRNLAIASEKVNAK
                     LVHISTDYVFNGFSKYPYREDNKTEPNSVYGKSKLMGEKFVEQFSHKYFILRTAWLYG
                     NGNNFVKTMIKLSLENKEVNVVNDQFGTPTSTVDLAKIIIRIMETEHYGVYHATCEGE
                     CSWYDFAKKIFELKNIDIKVNPIKSNEFKCKAQRPLYSVLDNFMLKLIGLNSFRKWEE
                     SIEEYLERYDINEK"
     gene            71824..72705
                     /gene="rfbA"
                     /locus_tag="PC466_000177"
     CDS             71824..72705
                     /gene="rfbA"
                     /locus_tag="PC466_000177"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HDF2767613.1"
                     /translation="MKGIILAGGSGTRLYPITKCISKQTLPIYDKPMIYYPMSVLMLA
                     GIQDILIISTPRDIKAFEELFGDGSSLGLKITYAIQEKANGIAEAFIIGEEFIGNDRV
                     SLVLGDNIFYGYGFSERLENAVKRKGATIFGYHVSNPNSFGVVEFDKDFNVLSIEEKP
                     TVPKSNYAIPGLYFYDNDVVEIAKLVEPSDRGELEITSINSEYLKRGKLKVELLGRGM
                     AWLDTGTHKGLLDASNYVEVVQTRQGLYIACLEEIAYTKGYISREQLMKLAKPLIKTE
                     YGQYLLKLASEDMQYGR"
     gene            72742..73299
                     /gene="rfbC"
                     /locus_tag="PC466_000178"
     CDS             72742..73299
                     /gene="rfbC"
                     /locus_tag="PC466_000178"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HDF2767614.1"
                     /translation="MGKINVIKTKIEGLYIVEPNVFCDERGYFMESYNKKDFIEQGLD
                     MCFIQDNESSSRKGVLRGMHFQVRYPQGKLVRVTEGEVFDVAVDLRKDSQTFGKWEGV
                     ILSDKNKKQFYIPEGFAHGFLVLSEKAVFNYKCTNYYYPEFEHGFIWNDKQISIEWPL
                     KGIEEIFLSEKDKKQKSFKDICIRR"
     gene            73337..74320
                     /gene="rfbB"
                     /locus_tag="PC466_000179"
     CDS             73337..74320
                     /gene="rfbB"
                     /locus_tag="PC466_000179"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HDF2767615.1"
                     /translation="MKKILITGGAGFIGSNFVHYMLNKYVDYFIVNLDLLTYAGNLET
                     LIEIQDSSNYKFVKGDISNREQMYKLFEEERFDIVVNFAAESHVDRSVENPDLFIKTN
                     IIGTQVLLDASIKYGVKRYHQISTDEVYGDLPIDRKDLFFTEQSPINPSSPYSASKAS
                     ADLLVSSYYRTYGLLTTISRCSNNYGPYHFPEKLIPLMILNALENKQLPVYGNGENVR
                     DWLHVYDHCTAIDLIIHKGNIGEIYNIGGHNERSNLEVVKMILNLLDKSEELISYVND
                     RPGHDLRYAIDATKIENELGWKAKYDFDLGIKETVKWYIENESWWKAVLSV"
     gene            74359..75027
                     /locus_tag="PC466_000180"
     CDS             74359..75027
                     /locus_tag="PC466_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HDF2767616.1"
                     /translation="MNEISSLINILALTQLSGSNTTNQCNCTYNSSSGFDMIMMTLLK
                     ALSQNNQQTSNGYNLSSNSENLFDELGSVVNNTASRFIDVDTKDKSVKSRIENAIEQA
                     SKKYNVDSNLIKAIIKVESDFNPNTVSSAGAKGLMQLMPENCRDLGVTDPFNIEQNID
                     AGTRHIKEYIDMFGGSIEMGLMAYNGGPGRMKSRGVESISDLYKMPKETQNYIPKVMK
                     YYRG"
     gene            75036..75464
                     /locus_tag="PC466_000181"
     CDS             75036..75464
                     /locus_tag="PC466_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaaR family protein"
                     /protein_id="HDF2767617.1"
                     /translation="MGINIDKLNISPSINMEVKKLKESNKFSDKLNSLKQSSSLEDIK
                     RNLESVKKAGERLVLTQNYGDISIYKNAVKEYLKSVVDNMYSLDKNSSFWEHQYYKNV
                     KIVDSKLEDMTSKLISEEKENIDIVSTVDMIQGLLIDMYR"
     gene            75488..75802
                     /locus_tag="PC466_000182"
     CDS             75488..75802
                     /locus_tag="PC466_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliM/FliN family flagellar motor switch protein"
                     /protein_id="HDF2767618.1"
                     /translation="MNSKKEDIYELNFGQLIEEKSGVIEENQNVFNAKVNVAVSIGNT
                     TETIKNILDLKEGSIIKLSKNVDEKLDIYANDRLFAYGESIITNEKLSVRLSKIEDSD
                     VN"
     gene            75954..76229
                     /gene="flgM"
                     /locus_tag="PC466_000183"
     CDS             75954..76229
                     /gene="flgM"
                     /locus_tag="PC466_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis anti-sigma factor FlgM"
                     /protein_id="HDF2767619.1"
                     /translation="MDIKNVSSNIVVNNYLKNTSGVKKVEEVKKINKTDKIELSKFAK
                     EMASVSNMSDENIRNKKVDEIKNALENGTYKIKPKEIAKKMIEDMRG"
     gene            76234..76650
                     /locus_tag="PC466_000184"
     CDS             76234..76650
                     /locus_tag="PC466_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FlgN"
                     /protein_id="HDF2767620.1"
                     /translation="MITDLKVIIYEEKNIISKMMELLKEQFDYIVEKDLENLNMLNPK
                     LEDISRELASIEIKRRQLFGDDISMSEVVENSNDRYLKEIYTDLKHILALAKNQQESN
                     DSLIKKELIFTKKMINFIKPADKQTATYNSYGNIRK"
     gene            76668..77978
                     /gene="flgK"
                     /locus_tag="PC466_000185"
     CDS             76668..77978
                     /gene="flgK"
                     /locus_tag="PC466_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-associated protein FlgK"
                     /protein_id="HDF2767621.1"
                     /translation="MAGLFSILNTANSGMNAHQKAIQTISHNISNLDTDGYSRQRTEF
                     ATNSPMYMPSLSNSIARGQLGTGVHVTDVTRARNSFYDYQFRAEAHKYGNTVSKYDYY
                     NTIETIINEPSDYGISAGIDDFFKGWESLAKDINSDSKKSLVVENASNLATLISESYK
                     KLNKLKGDIDDNINSEIKQINDMLKSLEDLNKSIDVISGSGSTPNDLLDERDRILDDL
                     SFKLDLENSDVKNMLSDGKLELNELKNADGTWKTGVSGTLQGLFEMHGKIDTYKSDLK
                     DVSDGLAKQINDVYNTSAGITVTDFFITSNVDGEDIIKVNPAIKSNPNELKLTADEAS
                     KIAKLKDEKIDIGVAGGKVSTISDHYKAFAESVGLDSQKVNQDEVNQRKIINNIDNSR
                     MSVSGVSLDEEMTELIKIQRSYQASAKVMSTAVQLLDVVINGII"
     gene            77997..78929
                     /gene="flgL"
                     /locus_tag="PC466_000186"
     CDS             77997..78929
                     /gene="flgL"
                     /locus_tag="PC466_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-associated protein FlgL"
                     /protein_id="HDF2767622.1"
                     /translation="MRVSTGMMSSNYLNSLQDNLQRLDKVNRQVNTTKEINKLSDNPY
                     KAIKILNSKSEIKTMETYVENCKDTGNWLETTDTALDQLGKLLSDIKKTLVASGDGAY
                     SDDELKTLSNETNEKMKEIANALNATHEGKYIFSGSNTGVPPVECIDNADGSVSLKFN
                     SSLNLNKLNDSLSMDIAQGISVDYNVKLSSLGFDPTKTDPFEELNNISKKLANPDADA
                     IKELTTTCLGDMEQLIENTVNVRSIYGTKANTVEAMKEKNDDSLIQLKDILSQNEEID
                     YGEKLVQLKAAELTYQASLQTGGKLFNVSILDYI"
     gene            78945..79337
                     /locus_tag="PC466_000187"
     CDS             78945..79337
                     /locus_tag="PC466_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar assembly protein FliW"
                     /protein_id="HDF2767623.1"
                     /translation="MMKVTLKKGILGFENLKEYELLDIEDNDSLKEFNSTEEEGIGFV
                     VVSPFEIINEYEIVLNQETIEKLEVKSPKDVVLFNIITLGQTFEESTVNMKAPIVINI
                     KTNFGMQIILQDDKYSIRHPLLRGDNGC"
     gene            79331..79543
                     /gene="csrA"
                     /locus_tag="PC466_000188"
     CDS             79331..79543
                     /gene="csrA"
                     /locus_tag="PC466_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011987028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon storage regulator CsrA"
                     /protein_id="HDF2767624.1"
                     /translation="MLVISRKKDEAVLIGESIEVKIVGVDGNNVKLAISAPNNISILR
                     KEIYEKVKSENIKATNKNIKILKSLK"
     gene            79565..79960
                     /gene="fliS"
                     /locus_tag="PC466_000189"
     CDS             79565..79960
                     /gene="fliS"
                     /locus_tag="PC466_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export chaperone FliS"
                     /protein_id="HDF2767625.1"
                     /translation="MYGENPYNSYKQNAVFMASKEQLLLMLVDGAVKYTKIARAAILD
                     KNTQKAHRELVRVQDIFTELMVTLDQNAGQWAKDMYKVYDFVRYELSRANIRKDIQVI
                     DNVLPVIEQIKDTWHEADKKSKEERSRYK"
     gene            79960..80316
                     /gene="fliS"
                     /locus_tag="PC466_000190"
     CDS             79960..80316
                     /gene="fliS"
                     /locus_tag="PC466_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export chaperone FliS"
                     /protein_id="HDF2767626.1"
                     /translation="MELNLAELDKLSKEELLLMLVDGTVKYTNISKEALLNNDYLKAH
                     NELIRVQNIFTELMTTLDQDAGQWAKDMYKVYEFIKSELAIADENKDIKIIDDILPIV
                     KQIRDTWHEVYNQLKI"
     gene            80337..81860
                     /gene="fliD"
                     /locus_tag="PC466_000191"
     CDS             80337..81860
                     /gene="fliD"
                     /locus_tag="PC466_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar filament capping protein FliD"
                     /protein_id="HDF2767627.1"
                     /translation="MSSISPIRVTGLSGNFDMEGIIEASMIRDKEKVDKAKQEQQIVK
                     WKQEIYRNVIQESKDLYDKYLSVNSPNSIVSEKAYSSTRITSSDESIIVAKGSAGAEK
                     INYQFAVSQMAEPAKFTIKLNSSEPIVRQFPPNASGASSLTIGDVNIPISEQDTTSTI
                     VSKINSLCADNDIKASYSEMTGELIISRKQTGSSSDINLKVIGNDNLAQQIANDNGIT
                     FANDASGNKVASVYGKNLEADVTDEHGRVTHISKEQNSFNIDNIDYNVNSKGTAKLTS
                     VTDTEEAVKNMQAFVDDYNKLMDKVYGLVTTKKPKDYPPLTDAQKEDMTTEEIEKWEK
                     KAKEGILRNDDELRGFVEDIQSAFFGDGKNIIALRKLGINESENYNKKGQISFNADTF
                     SKALIDDSDKVYKTLAGYSSNYDDKGMFEKLKDIVYEYSGSSTSKLPKKAGIEKTASA
                     SENVYSKQIAEQERNISRLVEKMNDKEKRLYAKYSALESLLNQYSSQMNYFSQAQGN"
     gene            81863..82198
                     /gene="fliT"
                     /locus_tag="PC466_000192"
     CDS             81863..82198
                     /gene="fliT"
                     /locus_tag="PC466_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FliT"
                     /protein_id="HDF2767628.1"
                     /translation="MDKLKEKLNLYKDISLQIINLIEKEEYIKISSKLGERQEIINSV
                     SEIDRNDFIQLYNRMELIEIDSRIRDILQGQLLEVKKELHEYKLTKQVNTMYYNLNRE
                     KVNIFNKKV"
     gene            82300..83172
                     /locus_tag="PC466_000193"
     CDS             82300..83172
                     /locus_tag="PC466_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellin"
                     /protein_id="HDF2767629.1"
                     /translation="MRVNTNVSALIANNQMGRNVNAQSKSMEKLSSGVRIKRAADDAA
                     GLAISEKMRAQIKGLDQAGRNVQDGISVVQTAEGALEETGNILQRMRTLSVQSSNETN
                     TAEERQKIADELLQLKDEVERISSSIEFNGKKLLDGSSTEIRLQVGANFGTNVAGTTN
                     NNNEIKVALVNTSSIMSKAGITSSTIASLNADGTSGTDAAKQMVSSLDVALKELNTSR
                     AKLGAQQNRLESTQNNLNNTIENVTAAESRIRDTDVASEMVNLSKMNILVQASQSMLA
                     QANQQPQGVLQLLG"
     gene            83265..85406
                     /locus_tag="PC466_000194"
     CDS             83265..85406
                     /locus_tag="PC466_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDF2767630.1"
                     /translation="MLLSIVMIVKNEEKILEKTLKSLTTLRSSIESELIIVDTGSTDD
                     TINISRKYTENVYFHNWNNDFSSMRNISISYAKGEWLLILDADEILIDSSTIVKFFKD
                     GLDKKFNSASIQLKNLYSYDKKLYGYCSVLRLFKNIDFRYHGKVHEQPIYKNPIFNNV
                     ADFEHYGYLFEDEEIRLNKVKRNEKLLFEELKENDNSPYTNYQLGKNFIILGKYHEAL
                     YYLEKSYELYSKLESAPGYLITSLVKTYLYLGKHKKCEKLCLKYIKKDMNNIDIYYYI
                     AQAQVDLGKYENSIDSYKRYIYLLDNYEISTQANSLFSDTDTVGLRDEAIITLIKIYY
                     KLEKYESVISEYNNIEDMEKKKNVYFSLFMSLYKLNRFEDIKNYYKEVSNSKIEKNSF
                     YKNIEEVINNIKDDEKEHVYKILCDIEGNYGILNQIRINKCVSIDKCKEILNEEKEII
                     YAYIIKVAFEDKIDLLDIFYEMEYVWIEKYLKYLLALERSFNLVLYKYIISRPNTSDI
                     KKIRVYKAISKVVLESISLSDEKYKEIFYLYIMYSYKYIRYIYRNLSDFELIKFVCND
                     LDKFTIEFKHLLDIKNKVNDANEKLEYIHSMRKLLNEYPFYNKIIKILISELEENIKE
                     SEEFKDLKDSFIISIENMIETGKINDAKSLVDDYSKTFMDDVKILNIKGILYMFENKL
                     DKADFMLKKALSLDVENEDTIYNIEYLKSLR"
     gene            85430..87307
                     /locus_tag="PC466_000195"
     CDS             85430..87307
                     /locus_tag="PC466_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDF2767631.1"
                     /translation="MNTPIVVNEKSKDIIKDWQYTYTNEDIKFTSIIILTYNQIEYTK
                     LCIESIRKFTPKNKYEIIIIDNNSSDGTVEWLKGQSDIKSVYNNKNLGFPKGCNQGIE
                     LATGENILLLNNDVIVTPNWLYNLNKALWSQDNIGAVGPITNACSYYQQIDVDYKSIE
                     DMFMFAHKINTSNINLWKYRLKLVGFCMLIKKSVLDNVGVLDELFTPGNFEDDDLSFR
                     MLESGYKLLLCQDTFIHHFGSVSFKENRNKYTDIMYINRRKFETKWGFNPEYSGMIRT
                     DLISKIDDSLEANINVLEIGCGIGATLLEIKNIYKNASIYGIEISESAGKLAKYSADV
                     LIADIEKVKLDYEKDFFDYIILGDVLEHLTDPWKIVNELKQYLKKDGCLISSIPNIMH
                     VSVLRNLVLGNFTYEDSGILDKTHLRFFTLNEITKMFNDSNYIINSVTATSMPLSEID
                     NRFIDTMCKESCKEMRQQYESYQYIVKATKSIDTKRYSSISMVNLKYALMRIDNELDV
                     DSNLSYIFDNYNITEPCFVDDIEYLVDTFVINKATLLNRLGVEAFNRGLGDFSINMFM
                     TVLEMDRDDIDSIYNITSVLCELEEFDTAYNLIKNSSKKVQSESDIQDILYFIEGKRY
                     E"
     gene            87300..89414
                     /locus_tag="PC466_000196"
     CDS             87300..89414
                     /locus_tag="PC466_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HDF2767632.1"
                     /translation="MNNDKICFITCVNDERLYEECLVYINSLDIPKNFSIETVALRGA
                     DSIASAYNKAMRETDSKYKVYLHQDAFIINKNFIYDILEIFKKNTDVGMIGVAGVKDI
                     PVNGIWWDSDKKAGKVYDSHTGKMDIYEFSNFEECFNEVMAIDGLIMITQYDVFWRED
                     KFDGWHFYDLSQSMEFRQNKYKVIVPKQNKPWCMHDSGVANINNGYDEYRIKFVKEYI
                     NLDLYRENFYEFDKKKASTILKSNKHVMDCMKEELTEQLRLKNYKDVLDIVSKIAHFS
                     VFNHTGLYSCEKCERALLECANNLPEIENTKLFTKKDLKRRKVLHVLSEGYSTGGHTR
                     LVKNWIEIDKDSVHSVVTTWQSDTLPDWLLKAIDDSGGEVISLDLISDDYLKRAVALR
                     KIAYDWADIVILYVHMWDTIPVVAFGVDGKIPILHVNHYDSTFWLGTSIADIVIDFSE
                     ASQLITLDKRGIDKSEILPMPLKEKEVFSKSEVRKRYNLEDDVTIILTIASERKYNSV
                     NDINYFKIAKTLIENTDNTIIIVVGVDTENLYWKTLSNVTDNRVICFGTTANIDDFYK
                     ISDIYLESFMVGSHTSKLDAILYDLIPVKFKNEVSPIFTNMWNFIDKFDYKNIKEVID
                     MIRRYNTSEFDRDKIKEKQSEIKHFVIDKHCIEIKNYIDKIYKEANHHKVKYDLYKND
                     EIEDYQLFVALYGYMVKNKNMS"
     gene            89423..90418
                     /locus_tag="PC466_000197"
     CDS             89423..90418
                     /locus_tag="PC466_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation glycyltransferase
                     FemA/FemB family protein"
                     /protein_id="HDF2767633.1"
                     /translation="MNNIHINKFEKSCEKNWDYFVENKSINGTFLQTRNFLNYHEEGK
                     FTDHSLIIYKGEEILAVVPACETYENGERVFFSHLGSTFGGIIIRSGFNDIRHVNAIT
                     NKLETYLQEQSFNKVYLKNTSRIFCKEDTSLLEYFLFKNNYMFYDELSMFLELSKYKK
                     DILANFRYSKRRYFKYSLKNNLTFKRLYSDEDIVCFFNLLSNCLDSKGAKVIHSVEEL
                     LEFKNNRLKDIVEFYAVYIDDIMICGSMVFNFQERVYHTQYLASNSTYNKYYPMIFLY
                     YNLIKDALERNFKYLSFGISTLNRGKYLDEGLATFKEGFGSSAICNRTYYKNINK"
     gene            90510..91742
                     /locus_tag="PC466_000198"
     CDS             90510..91742
                     /locus_tag="PC466_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HDF2767634.1"
                     /translation="MKRLMILGSIKYFENIVMSAKKEGIYTIVCDNRIDTPAKKICDE
                     AIDVDVFDFDKIKSIAIDKKIDGILTGFTDSLMKPYVYIANELNLPCVISCNQLESVT
                     NKAIMKKYFKNNAIPTTDYCIIESLKDLEKIQGLNFPLVIKPVDGYGSRGVYFVSNIE
                     ELIEKFEYSKEASQDGQVIIEEFYESEEIQGLAWVHNGESHVFYIGDRELVNIHTGRA
                     GKPDRLLYPSKYCFQYEEEIKSIYQNITQAFDIKNGPLYVQMLVGAYGIKVSEVMPRL
                     PGGCDYMAISQITDLDIGSLFANFSVNNEVNFDEIKKYNMHLSKCVYALPIYIRPGTI
                     KKINNIDKIENLDYVTQFLLLVKEGDTIGLYEDERQDCGRVYGIANNIFDANIKKKCI
                     HEMIEIFDENNENMIENF"
     gene            91762..92706
                     /locus_tag="PC466_000199"
     CDS             91762..92706
                     /locus_tag="PC466_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase"
                     /protein_id="HDF2767635.1"
                     /translation="MKLITHEQIMSLNISQKQGYEWIKESFLTKKDCQLPPKISMVEE
                     GHVFYNVMPSLNHNHMIGGIKMVTRLPGRNPSLNSDIFLYNMKDAKLKAILDGNYITA
                     FRTAAVAGLAIDTFAKKDFNTISIMGLGVTASAIMNMLSYTLKDKNINIKLLKYKDQA
                     ESFIKKYEKNEQFSFEICDTHEELIVDSDVVISTVTYTDEYLSEFKWFKKGALLLPVH
                     VMGFGNVDYLFDKVYLDDYNHLKHLENIDRYKYSCEFYNVLSKQAKGRENDDERIISY
                     NIGLSIHDILFANKIYELCETLNCEEIELKEPKEKYWI"
     gene            92800..93207
                     /locus_tag="PC466_000200"
     CDS             92800..93207
                     /locus_tag="PC466_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FdtA/QdtA family cupin domain-containing
                     protein"
                     /protein_id="HDF2767636.1"
                     /translation="MDKYNLIKFLSIGNEYIGNLVALESNKAIPFDIKRVYYIYDVPN
                     NVKRGFHAHKNLEQVLVCLNGSVKIKCYDGVKESIFNLHKNDVGLYIGTGVWHEMFDF
                     DEKTVLISIASEHYNEEDYIRDYKEFLKYLNNM"
     gene            93294..94385
                     /locus_tag="PC466_000201"
     CDS             93294..94385
                     /locus_tag="PC466_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS family aminotransferase"
                     /protein_id="HDF2767637.1"
                     /translation="MLVKFNNLLKQFQTHKEEYEQKIKDVMESGYYILGNEVRHFEEE
                     FASYVGSKYCVGLASGLDALIIAFRALGISEGDEVIVQSNTYIASVMGISINGATPVF
                     VEPNEYYNIDSSKIEEKINSKTKAILVVHLYGQASKMKDIQELCDKYNLYLIEDCAQS
                     HGAKYDGKMTGTFGDIGCFSFYPSKNLGAFGDAGAIVTSNEEIADKVKILRNYGSEKR
                     YYNKFVGYNSRLDEIQAGLLRVKLKYLNEIEIEKSKIVDRYLNEINNPKVILPKIENN
                     CTHVWHLFVLQVEKRDTFMEYLKKNGIESIIHYPIPPHLSEAYAYLGYKKGSFNIAEN
                     YSDKVVSIPLFVGMEDEEVSYIIKIINEY"
     regulatory      94694..94784
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            95191..95508
                     /gene="flgB"
                     /locus_tag="PC466_000202"
     CDS             95191..95508
                     /gene="flgB"
                     /locus_tag="PC466_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgB"
                     /protein_id="HDF2767638.1"
                     /translation="MNTYDIIKMGLDATNLRSQTIANNIANINTEGYKRHYVTFEETL
                     NDAMPKIEEKTDNSKGLRVDGNNVDIEEEKVNQAMATLQYNALISFANGKIAMTKSII
                     SGR"
     gene            95516..95920
                     /gene="flgC"
                     /locus_tag="PC466_000203"
     CDS             95516..95920
                     /gene="flgC"
                     /locus_tag="PC466_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgC"
                     /protein_id="HDF2767639.1"
                     /translation="MSVFSGMRISASGLTAESLKMDIISSNVANINATRGPNGEAYRR
                     KVVSFEENYDNKLGMLGVKVTSVEDDKSPLKEVYDPSHPDAKPNGYVEYPNVNILVEM
                     TDLITASRAYDSNVDTLNAQKSMISKALEIGK"
     gene            95930..96247
                     /gene="fliE"
                     /locus_tag="PC466_000204"
     CDS             95930..96247
                     /gene="fliE"
                     /locus_tag="PC466_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-basal body complex protein FliE"
                     /protein_id="HDF2767640.1"
                     /translation="MPITQINNLMQGAKLDNLIGETKPLTLNNKEEKKNFEDVIIDTI
                     DKVNFQQVTADDMKEKFIKGEDVSMHEVMLIGQEAQLSMQYLIEVRNKIHDAYQEMNK
                     VQI"
     gene            96272..97822
                     /gene="fliF"
                     /locus_tag="PC466_000205"
     CDS             96272..97822
                     /gene="fliF"
                     /locus_tag="PC466_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar M-ring protein FliF"
                     /protein_id="HDF2767641.1"
                     /translation="MIASFKNKIKEQVAKSRTKISSLKKGTKIALGIGVIAICLALVF
                     TAISASKNKYAVLFSELDVQDAADISAELESKKIDTKVKGSTIYVPRTEVDKLRLELA
                     PSLTGGSKGFALMDDSSSIGLTDEEFQIKKQRMIQGEIEKTIKSFPQVEDTRVHITFG
                     ESSVFEKEAIPGSAAVYLMLKPGTTLEKNQIKSVMALISGSVTNIPEKNVQVIDNKMN
                     LLSEGILEDEDVDENNQPTNSLINVDKNKASEQALNKQLEKSILEMLEPIFGKGKVKA
                     TVNADLSFDTAEKTEIKIDPDKVAIKETRSKNSSKSATNNVQGVDANMNNQGNNNGTN
                     TEDSLDESFEYETGKIETHTIVAPGELNRLTASVAIDGKIAKGVQADVEDIVNNAIGM
                     DGARGDTLSVVSMVFDPEGKAEAKQELEEIKKEGFKKNIIKAVIGVVAVVAIGAIGYL
                     IYKKRSEREDMDYEDEDYISKSDSVDRKDNPLLGDDPELTLEEAVKMYAEEKPDQVTE
                     IIKTWLNE"
     gene            97835..98905
                     /gene="fliG"
                     /locus_tag="PC466_000206"
     CDS             97835..98905
                     /gene="fliG"
                     /locus_tag="PC466_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein FliG"
                     /protein_id="HDF2767642.1"
                     /translation="MSTEITNVNAFDLSDINESDKKEKIEGEGLKKAAVLLMTLGPNV
                     SSDIIKSLPDKQVQKIGLEIANISSIASKERREILKEFVEINRAKDYVIEGGLEYARE
                     LLSNALGNAKANKLLEGISINTSTKPFKHIIKLDVKKILEILRDESAQTIAVLLAHME
                     PENGAEVLSYLDFDLQNEVAMRISSMGSISPEVIKVIESSLEDKLHSISGDDFKDYGG
                     VSTLVQILINSDRKTEKNILGTIEEQDPALAAQIKSHIFVFEDIVKLDDISIQKVLKE
                     VTMKDLVYALKGVDDEISDAIYRNQSSRAADALKEEMEMVGVIKVTQVEAAQQKIANI
                     VRKLEREGAITIVRNFGGDFVE"
     gene            98898..99629
                     /locus_tag="PC466_000207"
     CDS             98898..99629
                     /locus_tag="PC466_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar assembly protein FliH"
                     /protein_id="HDF2767643.1"
                     /translation="MNNKIIKSKKASYKGVLDLTIIDKVRVGESNVNKENDCRFRDEV
                     IKEAIESAEIKKNEILEEAKMNAQNIEKQAYEKGYSQGQKNGYEDGYKESYDEYTQKA
                     KDEADFIKNQADLILLQANEKMTEYIKEKNKEIVRLAINMASSVLKKHFEDEESMSDL
                     LKQIIQDYEGSSSFIVRCNSFYKDNIEKEFELFKEETSLKSSVFVIADDSIDKGNAII
                     QKENGRIIVGIDCAMEKLKEELLGE"
     gene            99633..100952
                     /gene="fliI"
                     /locus_tag="PC466_000208"
     CDS             99633..100952
                     /gene="fliI"
                     /locus_tag="PC466_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein export ATPase FliI"
                     /protein_id="HDF2767644.1"
                     /translation="MYKTDISIDFDKINKKIENLELTISEGRVKKIIGLTVEVEGIKA
                     FVGELCVIYNQVNKPVNCEVVGFKDKEVILMALGELTLIAPGCKVISKGIPLSVMCSD
                     NLLGKVLDGLGNPIDNSDAVLGDRYNLNNEPPDPMKRKKIRNIMETGVRAIDAFTTCG
                     EGQRIGIFAGSGVGKSTTLGMIARNAKADVNVIALIGERGREVLDFIDKDLGEEGMKK
                     SVVVCATSDKAPLVRLKGALTATAIAEYFRDQGKKVILMMDSVTRFAMAQREVGIAIG
                     EPPAQKGYTPSVFAILPKLMERTGTSDKGSITAFYTVLVDGDDFNEPIADTTRGILDG
                     HIVLSRDLANKNHYPSIDVLNSLSRLMNEIASKEDIKIASFARDMLAEYREAEDLINI
                     GAYASGTNKKIDEAIYYHEHIINFLKQGINEKSSFNETISSLRRIFE"
     gene            100984..101430
                     /gene="fliJ"
                     /locus_tag="PC466_000209"
     CDS             100984..101430
                     /gene="fliJ"
                     /locus_tag="PC466_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012815984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export protein FliJ"
                     /protein_id="HDF2767645.1"
                     /translation="MELDKNFKFRLQKVLDLKIKDEEEIKMEFAKIQQKKIDIESNLE
                     NLESNYSKYSISKNNDSVQNQKITINYLLALNNSIMDLSEELDKSTNELEKARKQLIS
                     KQIERKSLEKLKEKKYGQYYKEEQLKEQSTNDEFASMSYLRNRQVL"
     gene            101458..102663
                     /locus_tag="PC466_000210"
     CDS             101458..102663
                     /locus_tag="PC466_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-length control protein FliK"
                     /protein_id="HDF2767646.1"
                     /translation="MKIQADSYNIIKDIGNRKSSSKNKNIKNNKFEDNLYKATDHKKV
                     KDRRETSKQNVSSDKRENSDNECHLDEDKSNHLEDENTYEKDCSNNNEALHQLLNLLK
                     DNYKKDKDINTILNNLKKLSISDELKQELKLNKNILNKIANQNLELNRASTNNPNDIE
                     NLDIMKLRELLENNASEDIEVISKTTENDTKSIDLYSFDSNRIDTLNSNKQKDDSSDI
                     LEKLAGVNGNKSGNFGQVINKSVDMNKIKNDNVNLKQIESNVMDDSIKAIKHMKTNDI
                     QELTIKLRPKELGDMNIQLLKDGESMRAVVTVFNKDVFDSINKNIADLKQHLELTNVN
                     IKDVSVQMHSDNTNTSDTFDKAFEQQNRQNNQENMSKQNTNDKRNNVVIEDEIKENII
                     DDDRVDLLA"
     gene            102681..103289
                     /locus_tag="PC466_000211"
     CDS             102681..103289
                     /locus_tag="PC466_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlgD"
                     /protein_id="HDF2767647.1"
                     /translation="MYGIATALAGTQVNYRSNNLSQLERNINDIANKQVRSKGNQTVT
                     DNGTPIIGQGDDADKDLFMKILVAQMGNQDPMNPQDPTEYVSQLAQFATLEKMSAMND
                     KLDILLALSNSTLINSALSMATSLIGKEVEVSGEEEEDENIVGVVKSTYIKDGEVHLE
                     LEVDGSDKTVGVKYEKLLKIGEVDANSGEENDSSEQESPEEV"
     gene            103316..104299
                     /locus_tag="PC466_000212"
     CDS             103316..104299
                     /locus_tag="PC466_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-basal body complex protein"
                     /protein_id="HDF2767648.1"
                     /translation="MIKAMYSGVSGMKANQTKLDVIGNNVANAGTTSFKKSSARITDS
                     FYQTVLYASAPTAALGGTNLGQVGVGSKISSINKDMTQGNVQPTNRPSDLMIDGDGYL
                     PVVRQGTVMYTRDGSFNLDTGFKAADGALKNIKGGRLVNGDGYMLQGVIYDGEYKADT
                     GEFIKKGDAKGKEPIVIPLQSISPKDGTVQNVLEYNISKDGTVEFLLSDGQRTQFVYD
                     IPDGAKVGDTPAGIDKLKGTIQKVQTYAFQNPAGLDAEGGNLFKPSANSGDPQIAGAT
                     GNIIQGAIEASNVDIAEEFTEMIIASRSFQANSKIISTSDEILQEIINLKR"
     gene            104312..104515
                     /locus_tag="PC466_000213"
     CDS             104312..104515
                     /locus_tag="PC466_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar FlbD family protein"
                     /protein_id="HDF2767649.1"
                     /translation="MIRVTDLNGRRYILNSDLIVRIDSVPESRILLTTGEKNLVKESV
                     DEIVDKVIKYKRKVNVGYIRSEK"
     gene            104515..105333
                     /locus_tag="PC466_000214"
     CDS             104515..105333
                     /locus_tag="PC466_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MotA/TolQ/ExbB proton channel family protein"
                     /protein_id="HDF2767650.1"
                     /translation="MKKTDSLTFIGLILSTVLVLFGAVKGSSSGLKSFFDFASILITV
                     FGSFGALMITFTIDDIKLIKDALQYSFKTMNISKLDLLNQFKTLSKKARREGLLSIES
                     DVMKIQDPFMKKGLELCIDGLEVNEIRSILELEIDSVEETNNRYSKLFKTWGTFAPAF
                     GMLGTLIGLIQMLSDLTSPDLIASGMGKALITTFYGSLLANIALNPIAYNIDEKTEKE
                     IYVKEMMLEGIISIQSGESSIVVEERLATYLSNNEKLEIMKSNKNTERAMSNGA"
     gene            105323..106018
                     /locus_tag="PC466_000215"
     CDS             105323..106018
                     /locus_tag="PC466_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HDF2767651.1"
                     /translation="MARKKNKKKDEINPDAWLATYADTITLILTFFVLLYATSVVDME
                     KFKNIADALKGQFSGISMFSTGSSTSEKSPIESVLVDKNDKSNLEQDLKDKVNNSNLQ
                     NSVTVKDDSRGILLELDDSILFDSGISELKADSKATLNKVYDMIKMMKNKIVIEGHTD
                     NVPVKSSTHESNWDLSSSRAVSVVRYFVEEKGMDPRLFSATGCGEYQPLVSNETAKGR
                     AENRRVNILITID"
     gene            106030..106473
                     /locus_tag="PC466_000216"
     CDS             106030..106473
                     /locus_tag="PC466_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body-associated FliL family
                     protein"
                     /protein_id="HDF2767652.1"
                     /translation="MFKNKKIIIIILILIIFSAGAGFFILGEGGNKQIDKIAGLFIPT
                     GKGKDEVKTENLDLEEMVLKLADEGVRYLKVSITVSYDSSYKDIEKNTPLIRDNIINC
                     FMAKRADDFTADNLKNIKEEIKNTLNIQLGENVIQNIYFTNIVVQ"
     gene            106488..106862
                     /locus_tag="PC466_000217"
     CDS             106488..106862
                     /locus_tag="PC466_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliO/MopB family protein"
                     /protein_id="HDF2767653.1"
                     /translation="MILYLLKILICIPIILILIVLSLKISQGTLLKKYNDKYIKILDI
                     VNISKNNSIIILKIGEEGCIMASSSSSMNKIKDLTKEEILRIENDIKERNFKIQDFKM
                     ERIKKKYDFSRYIGKFTKKEDK"
     gene            106863..107528
                     /gene="fliP"
                     /locus_tag="PC466_000218"
     CDS             106863..107528
                     /gene="fliP"
                     /locus_tag="PC466_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425215.1"
                     /note="The bacterial flagellar biogenesis protein FliP
                     forms a type III secretion system (T3SS)-type pore
                     required for flagellar assembly; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar type III secretion system pore protein
                     FliP"
                     /protein_id="HDF2767654.1"
                     /translation="MELLSKLPLADVPYTSSMQLFLFLTALMFLPFVMFMMTSFVRIV
                     ISLSFLKSALGAQQAIPSQILVGLAIVLTIFIMRPVLNEINEKALQPYMKEEVTMEEA
                     MKEAEGPIKEFLLKQTRQTDLDLFVEQAGLKEKKLTRENIPLSVVVPAFAISELKTAF
                     QIGFLIYIPFLIIDLVVASVLMSMGMFMLPPVMISLPFKLLLFVMVDGWNLIVKTLIL
                     GFG"
     gene            107541..107810
                     /gene="fliQ"
                     /locus_tag="PC466_000219"
     CDS             107541..107810
                     /gene="fliQ"
                     /locus_tag="PC466_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FliQ"
                     /protein_id="HDF2767655.1"
                     /translation="MSEFMIMSVLKNGMFTGAMIAAPVLIVSLVVGLLISVFQATTQI
                     QEQTLTFVPKLIAILLVVAIGGSWMLHTLISFTSEIFNMMSLITK"
     gene            107822..109636
                     /locus_tag="PC466_000220"
     CDS             107822..109636
                     /locus_tag="PC466_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fused FliR family export protein/FlhB family
                     type III secretion system protein"
                     /protein_id="HDF2767656.1"
                     /translation="MIFVFIRIVAFFGTLRILFPAGTPALFKSLFAIIISILISSTMQ
                     IEYATNIDNIVLFTLYGINETITGIMLGYITNLCFYSIRMAGSMMDQQMGLSMINMFD
                     PNSMTQTTLIDNLMNWTARMIFFSMDGHHVLIRGIRYSFELIPIGKSFVDNNIDYIIN
                     IFVQCFLTGFKIAIPIVLCLLMADFILGLISRSVPQLNVMIIGMPLKILVGIALFIIS
                     IPLIVNQISHLLSQIPKMYEGTFALAPMFFMGSTDKTEEATPKKKGEQRKKGNIAKSK
                     ELPVAMTLLAFTLLVPTLFSYVVDTLKSSLNYFLSLDFYMNINYSSIEKLVIAGLMDF
                     FKIFLPIAIPFLVLGIVANLFQVGILFTGETLKPNLSKLNPVSGFKNMFSMRSLSTLI
                     KDTAIISILAYIGYTFFQDNYLDILKLGNIYLPTLMYTVKDLVYSILSKICVAMIVIA
                     VADYVYQRYSHKKQLRMTKQEVKDEYKNSEGDPEIKAKIKQKQRQISSQRTMQAVPSA
                     TVIVTNPTHLSIAVRYEKGKDQAPVVVAKGADYLAFKIREIAKGNDIPIIENKPIARL
                     LYKQVEIDQEIPEDMYQAFAEILVAVYKIKNRYKVLKR"
     gene            109645..111720
                     /gene="flhA"
                     /locus_tag="PC466_000221"
     CDS             109645..111720
                     /gene="flhA"
                     /locus_tag="PC466_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlhA"
                     /protein_id="HDF2767657.1"
                     /translation="MNKFNLKENMDVIVAFGVVGIVLMMIVPLPTFILDILLAINISL
                     SVLILLMTLFTTNVLDLSIFPTVLLVTTLFRLGLNLSSTRLILTQGYAGEVIEAFGSF
                     VVGGNYVVGIIIFLIILIVQFVVITNGSGRVSEVTARFTLDAMPGKQMSIDADLNAGV
                     IDDKTARKRRKELQQEADFYGSMDGANKFVKGDAIAGLIVTAINIIGGIVIGAVMLNM
                     TLMGAAQTYVRLTIGDGLVSQIPALLISTSAGIIVTRASTDENFGGLVSKQLTAIPKA
                     VMMTGCVLIVLGMMPGLPKPAFFSLGIGAIAAGYFLGREKKDTLEDLEFEKPDMVNPD
                     KNEVEDVTNLINVESIEVEIGYGLISLADESAGGDLLQRIASIRRQCAIDMGIVVQPI
                     RIRDNLQLNPNQYNIKIKGNVVGGYEIMPNMVLCMDPMNQGFSIFGIKTIEPTFGIEA
                     LWIESDKVEDAEIKGYTVVDSSTILITHLLDIIKSNAHELLGRQEVKTIIDAARENYS
                     AVVDELIPDLMTLGEIQKVLKNLLREKVNIKDRVTILETLADQSRNTKDIELLTEYVR
                     IALARSICNNLVDDDKTIVVATLSPETEELVSNNLQRSVNGTYPAVDPENTNKIFESI
                     QEVMNNVYFNHNIPVIVVSPKIRAPFRKLVEIVYPNLTVLSLNEIPNDIKIKAEGVVS
                     IYDDEKVYS"
     gene            111695..112711
                     /gene="flhF"
                     /locus_tag="PC466_000222"
     CDS             111695..112711
                     /gene="flhF"
                     /locus_tag="PC466_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlhF"
                     /protein_id="HDF2767658.1"
                     /translation="MMTKKYTANTIQDAMNLAKMELGDNITLIDKKEVRKSGIQGIFS
                     KKDIELTIGWEKRENVEQKDLKREIEQLKLIINNMGFDNKNDNDIDKICKNLLSLELN
                     EEIVESIRIDLQEMKFNGIDTSKNLVEILKKKIKIENQAINGKIALVGPPGVGKTTTI
                     AKLAAKLVFEENKKVGVITIDTYRIGAVEQLKIYTDIMNIPFKGVISPDEMELALDEM
                     KDCDVVLIDTTGRGYKNSMQILEIKNLIDKAETDNIHLVVNCTTRESDTKAIIDSYRN
                     VNFKSLIITKLDETITYGSIFNIMNYAQKPISYITTGQNVPDDIIKPNEDKIIRLLLG
                     VESI"
     gene            112708..113586
                     /locus_tag="PC466_000223"
     CDS             112708..113586
                     /locus_tag="PC466_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MinD/ParA family protein"
                     /protein_id="HDF2767659.1"
                     /translation="MIDQAQILRKMAMEKRGLDEFIVENENVPKIITIASGKGGVGKS
                     NLATNLSICLTKLNKKVLILDADIGMSNIDIIMGVNVKGTIIDVINGEKNIEDIISQT
                     KYGVNIISGGSALNHIEDFTEAQRNKFIHSIEQIHDVDFIIIDTGAGMSKSLLSFIYC
                     STEFFLITTPEPTSLTDAYSLLKAISNFGIKRSANIIINRVIDLEEAKSTYKRIKMVV
                     DKFLNLNLELYGYIIDDKKVSLCVKKQIPFILEYPTSIASKCIIAIAKRMVSQSREDI
                     VDNKSFLRKMFSIFKS"
     gene            113600..114301
                     /locus_tag="PC466_000224"
     CDS             113600..114301
                     /locus_tag="PC466_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliA/WhiG family RNA polymerase sigma factor"
                     /protein_id="HDF2767660.1"
                     /translation="MNREELIKENMPLVKSIARKFFIPGKGFEYQDLVNSGVIGLIDA
                     INKFDAEKGAKFSSYSYIKIKSAILDEIRNQSPISKHNLTKVNKYNRVVEKLQSKLLR
                     EPTSYEIAKELNVSEKELHDIESNIDMLNIVSLNYVIFEDTNETVQDVISDREEEAPE
                     NIIEEEEKLEILSKAISNLNEREKLILSLYYYEDLNLKEIGKVLGVSESRVSQLHRKS
                     IRNLRNKIKELKYSI"
     gene            114317..114739
                     /locus_tag="PC466_000225"
     CDS             114317..114739
                     /locus_tag="PC466_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein"
                     /protein_id="HDF2767661.1"
                     /translation="MIQIILIVVSILIIVTIVINLHKESKNKDNRYFDKIFEQEYEAN
                     DRLIIAEKRRFFLDKVLAEIRSNNHIKVYENYNLIKANEERKENIFIESKKEVRQENE
                     LSLKVKHLISSGYDDVEICKMLDIGKGELSLIRSCYKI"
     gene            114724..114909
                     /locus_tag="PC466_000226"
     CDS             114724..114909
                     /locus_tag="PC466_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein"
                     /protein_id="HDF2767662.1"
                     /translation="MLQNIRILLCDKKVFLGIGIGILISTLCIMLFSNNDMSKAEIEK
                     KARALGMKYTSEMKVLE"
     gene            114950..115723
                     /gene="flgG"
                     /locus_tag="PC466_000227"
     CDS             114950..115723
                     /gene="flgG"
                     /locus_tag="PC466_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgG"
                     /protein_id="HDF2767663.1"
                     /translation="MIRGLYTAVSAMITNQQKQNVVVNNLANMDTNGYKSKQLLTKSF
                     DELKLEGYNNYANGTKQKQIIGDISPGISMDETITNFNQGPIKTTDNKMDVAIQGKGF
                     FLVSDAAGNQFYTRNGNFRTDNQGDLITSEGYYVLGTNTATGAVGHINVGNQKFEVAK
                     DNTISLDGNAMYKFNIVDFNDYNNLKKEGDNLYSGGGAMKVNNALTIQSAIESSNVDM
                     VSEINNMMTISREYEANQKIIQAMDSKLAKIASEIGSVR"
     gene            115744..116505
                     /gene="flgG"
                     /locus_tag="PC466_000228"
     CDS             115744..116505
                     /gene="flgG"
                     /locus_tag="PC466_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgG"
                     /protein_id="HDF2767664.1"
                     /translation="MYTMFYTSKTALSANQSKLDIISNNIANSDSTGYKKINMEYSDL
                     VDEVLNRPSYPTNGNDISTGTGAKATAPMRIYEQGALAPTDSKSNLAIDGEGFFRVIR
                     KDGTYAYTRNGGFNIDGLGKIVDDNGNILDVQFDAGYNYNNTNIDSTNLTVSRNGELF
                     VDNKKIGKINLYQPIGTQNFISEGDSLFVATDAAQIKQVEKVDIVQGYRERSNVSLQE
                     EFVDLIATQRAFQMNSKGIKTADEMWQIANNLRAK"
     gene            116528..117409
                     /locus_tag="PC466_000229"
     CDS             116528..117409
                     /locus_tag="PC466_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliM/FliN family flagellar motor switch protein"
                     /protein_id="HDF2767665.1"
                     /translation="MNDMKEYDFGKPQSYSRENLTCLNFLLAEFCKKYKNYIIYELKC
                     NSSMIVDSIDQVNYQTFLDRVTSSCVVVQNAMEPVMKNFSFRIDRSVADMWIDITSGG
                     TGVIKDNDRELTELDKKVLLHLMDDLVRNMHLFEGFENIQVLDTHTHINLPQLCSPTA
                     PVCVVDLKVLNDNEYIGSVSLCFPYNGLEALLESISVIEFFDNDVGDDSEEFTKKIYN
                     SVSNIELSVIAEIGKVSINVEDLLKLEVGDVIVTNKKINDYIDIFVENSKSYTATPGF
                     ISSKKGVKINDAVGKEV"
     gene            117412..117786
                     /locus_tag="PC466_000230"
     CDS             117412..117786
                     /locus_tag="PC466_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliM/FliN family flagellar motor switch protein"
                     /protein_id="HDF2767666.1"
                     /translation="MDNSNLISDEEAKMLLNDKVESEVDGDDELALDVSEVNRNNIQR
                     ILDLKLELSVVIGRTKMTLRDILNLHKGSLIELNTLADQDVEILIDNKVLAYGKVVVV
                     DLNFGVKITSIVSEEDMVKSLV"
     gene            117818..119221
                     /locus_tag="PC466_000231"
     CDS             117818..119221
                     /locus_tag="PC466_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HDF2767667.1"
                     /translation="MVLILNLNDIKKDILKLNKKDSCSLYNESINNINNNCISTGLKF
                     LKQARDLNPDDVDILNLTGLVNLLKCNFDDAVESFYKSSLCEKTALCEKYINMLTSEE
                     FLIFFEKYNQLIRLINKGMYKEAIQGFKLITDQYCDLIEPYELLALLYDKEEEYIKFD
                     ECLEVLKIIDKENYLLNQENNTLDMYNSANIQTKSNVKVDDYKNEFLHKSSSNHKIND
                     YNNVTKEKSSSKNQKSSDSNKKKSIKKNKYLYIAIILGILLVGQSIYSSYKMNNLTDK
                     ISKNNETKNEESIDSNLTKKENNIEENEDMSKASNINKSNKNINKEADVKSKKNTVEN
                     EDDKDSDLFTEDELMSKANTLKSEKKTKSSIQLYKKVADIGENKGNTSEATYQVAILS
                     EKLKDYKTAEEYYKMYVENYSEKDAYFDESYYNLGMMYYNNGDLKNSKLTLKKLVNKV
                     PNSMYNNSKVKEILKEE"
     gene            119337..121274
                     /gene="htpG"
                     /locus_tag="PC466_000232"
     CDS             119337..121274
                     /gene="htpG"
                     /locus_tag="PC466_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone HtpG"
                     /protein_id="HDF2767668.1"
                     /translation="MEFEKGSISIHTENIFPIIKKWLYSDKDIFIRELISNGCDAVSK
                     HKRLVSLGEISENKSSDYKITVSVNKGEGTLKFIDNGIGMTEEEIKKYINQVAFSGAE
                     DFFNKYKDKMEESNDIIGHFGLGFYSAFMVSKKVQIDTLSYTEGATPVRWISEGGTEY
                     EISESDARNDRGTTITLFIDDDSKEFLDEFTVRGIINKYCSFLPVEIYLEDVERLERE
                     AKEAEEKAKKQKEDGKEEIVDAKVIEPLNDTNPLWLKSPKDCTDEEYKEFYRKVFNVF
                     DEPLFWIHLNVDYPFNLKGILYFPKLKNEFELTEGKVKLYNNQVFVADNIKEVIPEFL
                     LLLKGVIDCPDLPLNVSRSFLQNDRDVSKISKHIIKKVADKLKSLCKNEREEYNKFWD
                     DIQIFIKYGCLKDESFYEKVKECILFKTIDDEYITIQDYLEKCKDKHENKVFYVSDKE
                     QQSQYIKLFKEYDLSAVVLNSSIDTHFISFMEYKENGVKFNRIDADLSDVLKDKNENK
                     DSEENKEEIAKIEGLFKEAVGERVKNYSVEGLKNEDTPAMVLVSEQSIRMAEMQSRFA
                     GMDLGMNFEEEKTLVINENSPIIKKLVSLKDDEEKKDKITLICNQIADLALLSNKELK
                     PDELDSFVQRSNKLMSLLIEL"
     gene            121662..122792
                     /locus_tag="PC466_000233"
     CDS             121662..122792
                     /locus_tag="PC466_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HDF2767669.1"
                     /translation="MNFNYNLPVNILFGRGRINDVGKEVSKYGKKVLIVTGKNSTKKT
                     GLLDKTIDLLKDSKIEYEVFDRVEQNPLITTIYSGVEIIKSTGCDCVLGLGGGSIMDA
                     AKSIAFSYKNPGDLNDYIFGIRQGEEALPIILVPTTSGTGSEGNCFAVLTNSETKDKK
                     SIKKNSMYAKASIIDPELMVTMPKHIIASVGFDALAHNMEAYLSNGRNPLADVQAIYG
                     IELISENLIKVYNDVNDLEAWEKITLASTIGGMTIGTAGTALPHGMEHPVSGLRDVMH
                     GKGLAALTPTIIESSWDIDIERFGNISKVLGGTCAEDCSDAIRNFLKKIDLDIKLSDL
                     GIEKSDIDWLTDNCMKISVANIKRHPKYFNKEQIKEMYHKSL"
     gene            123019..124041
                     /gene="splB"
                     /locus_tag="PC466_000234"
     CDS             123019..124041
                     /gene="splB"
                     /locus_tag="PC466_000234"
                     /EC_number="4.1.99.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore photoproduct lyase"
                     /protein_id="HDF2767670.1"
                     /translation="MFNPKRIIFEKGTLDTDVGKKIYNKFRDNKDVEIINISSNRIKE
                     HIPGENLYEQYRSGKQTMVVGIRKSLKFQTCKPSANYQLPLVSGCMGRCEYCYLNTQL
                     GDKPFIRVFVNVDEILEQTKKYIEDRKPQVTIFEGAATSDPVPVEPYTNSLKKTIEFF
                     GREEKGRFRFVTKYSDVDSLLDAEHNNHTEIRFSINTPRIINEHEHYTASANKRIESA
                     VKLARAGYQIGFIIAPVFLYEGWKEEYKNLIISIKEALPKDFDKKIIFEVISHRYTTK
                     AKNRILEIYPDTLLPMENEDRKFKYGQFGYGKYVYDKEQLDDMKEFFLKEINGVFKNS
                     LIKYII"
     gene            124223..125134
                     /locus_tag="PC466_000235"
     CDS             124223..125134
                     /locus_tag="PC466_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDF2767671.1"
                     /translation="MHAWESIQITLDLIEANLSEEISINELANKANLSPFYYQRLFKR
                     LVNKTVMEYIKLRRLARASEYLAEHKNRILDVALNFGFASHETFTRSFKKAYGLTPEK
                     YRANPVKLNHFIKPELILNYAMVDEGVPLIADDIVIEVNRKTLSNPRTFVGIEIEVPI
                     CQLVGGETTGIAIVEELWMKLGSQRHNIPNQIPGGNEFAALYMGNAKEGNCMYMAGVE
                     VESGTSVEGYNTFELPAKEYLVCGFEAENFNELVNSAVFKADKFMERWMKKHNLTTTD
                     FAIEMYYPTTPEAAYLEHWIVPVPIEQ"
     gene            125149..125565
                     /locus_tag="PC466_000236"
     CDS             125149..125565
                     /locus_tag="PC466_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3788 domain-containing protein"
                     /protein_id="HDF2767672.1"
                     /translation="MNWQDAFFQDTKPTFEQINEFINNPLWDKLNKTLVSTYNVEPKL
                     EYSKCSMQRGWNVKYKKRGKSLCTLYPQEGYFKALVIVSESNRVEVDLFINTCCDYIK
                     KIYNEVNFFNGSKWLMIQVDSLLVLNDMLELIKFRA"
     gene            complement(125659..126051)
                     /locus_tag="PC466_000237"
     CDS             complement(125659..126051)
                     /locus_tag="PC466_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2767673.1"
                     /translation="MSINTEKNITKNVEELTCPIRYALDIVGGKWKLPIICMLAVENP
                     IRYSSIKRKLDGITNTMLAQSLKDLESTGIVHRKQYNEIPPKVEYTLTSKGKSIVPIL
                     QQFANWGATNMQEKNTCGLSCKECRKIK"
     gene            126192..126587
                     /locus_tag="PC466_000238"
     CDS             126192..126587
                     /locus_tag="PC466_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HDF2767674.1"
                     /translation="MKALEFLNKAGVYYLATVDENNQAHVRPLGFVMEYNGKLTFCTS
                     NQKDMFKQLIFNPKVELCCIDQNLNTLRILGEAVFVTSKETQAKALEIMPSLGQMYSV
                     GDGKFEIFSIDKAKVSCCSMSGKKIDVEL"
BASE COUNT        50009 a        13839 c        22201 g        40722 t
ORIGIN      
        1 ttatgagaag taatagtata aaatattatt gaattttttc tctcgaaata tataatttag
       61 aatcttctga tttattttta tgctcgattt ccttattttt tttcataaat atatatagag
      121 gagctattaa caacattgcc cctaatccta ttaagactct attttgagtt ataggttttg
      181 aaatatcttc tgcccaagct tgttgtaaca accataagct acctaaaata gctaccattg
      241 gtataacagg accaaatgga atcttaaaag aggccttaac atctgttctt tttcttaaaa
      301 ctattactga taaacaagtt ggtatgtact gagcaaatct tgcaattaca ctcattactg
      361 caagttgttc aaaacttcca gttagcacaa gtggtataca acaaattaaa gatattatta
      421 ttgctacata tggagcacca tatttatttg tttttcctat aaatgcagga agagaacctt
      481 cttctgctag agaagaacca catttaggag ttactattga tgaacctata tttataccaa
      541 atatagatat taatgttgct acagatatga aaactttacc ataattgcct aaaaatacac
      601 ttgaagcatc tgcaattgga atactgtttt caaatagtct atctccaagt atacccatac
      661 agacaatttg aattaatata taaattattg cacatataaa tattgtggtt attaatgcga
      721 ttggaagatt ttttttagga ttttccattt ctccacttgc cacaataaat gattcaaagc
      781 cggtaaatgc gtaaaatact aatataatgg ctggacccat actagagtta actacatttc
      841 ctgaaggaac aatatttaca aattttataa agaatattcc aactatcaca aaaactatta
      901 atggtactaa tttagctata gttattacat tattcattat ctttgtgctt ttaattccaa
      961 ataagctatt tattgaaagt agtgttacga gtattgcagc tatacaacct ttgtattcag
     1021 tggcagattc tggccaaaat gaacctaaag ctgttgcaaa tcctactgct agagtagacc
     1081 atgatataat tctaataaac caagacattg taccaacttc aaatcctata aaatctccaa
     1141 aagctttttt ggagtataga tatgctcctc cattcttatc aaacatgctt ccaacttctg
     1201 caaaacataa aagtattgat agaactaaga gtgtagcaaa aatgtatata aacatactgt
     1261 tttgacctgc tagactataa actttacctg gtagtaagaa tatacctgaa cctattatgc
     1321 tattaatccc taataatatc atactaaata gacctaattt cttagctttt tccatattaa
     1381 tttatctcct attcttttat taattactgt actaattaaa atacaaagta ttcattacat
     1441 gcatcataac acctattggt aaacaatctt catctatatt gaagctagag gtatgaagag
     1501 gtgaaattaa gcccttttcc tcatttttac atcctaaatg gaagaatgct cctttacaat
     1561 gttctgtgta aaaagaaaag tcttcaccac ctaaagacgg gtttggtctc aatataaatt
     1621 tttcctctcc aagtaattct ttagtacttg atataactgt atctactaat tctttttcat
     1681 ttataacagc aggatagttt tcatcactta catgtaaagt cccaacacaa ccaaatgcag
     1741 atgcagtgtc tccaacaatt ttagctattt tatcaatcat aaagtttctt gttttgctat
     1801 ttaaggttct taaagtgcct tctagtttta catcttcaca tattacattg tgtgcatcac
     1861 caccatatat tttacctata gtcaaaacgg cagcattatt tggttctaag tttctactta
     1921 ttatagtttg taatgatgta acaatttgtg aagctgtaac tattgcatca ataccatttt
     1981 caggatatgc accatgagct cttttacctt tgatacttat ttttatagtg tctacactag
     2041 catttaatgt atcatatttt gtttcgataa ggcctgtttc tatatgtggc ataacatgaa
     2101 gtccgaatat ataatcggcc ttggggtttt ctaaacaccc atcctcaact aaaaattttg
     2161 ctcctccaaa accttcttct gctggttgaa ataagaattt tacatttaca ttaagtttat
     2221 cttttattga atgtaaaact ttacatgctc caagtagcat ggttgtatgt gcatcgtgac
     2281 cacaagcatg catttttcca gaatgtattg atttataagg tatgttgttt tcttcttcaa
     2341 taggaagagc atccatatct gctcttatac aaatcgtttt atctgcactt tcttttaaaa
     2401 tatatgccat aattccattg tgttttgtaa attccatata atcaattccg atttctttta
     2461 aataagaaat taccttctgt ttagtaagat tttcttcaag agctaattct ggaattttat
     2521 gtaattctct tcttatgttt ataagccatg gttttataga attacaactt tctattacaa
     2581 aatcttttcc taattctttg gtttgatatt ttaatttcaa agcctgttgc atttttattc
     2641 ctccaattgc tttttattgt tttattaata taataagcaa ttattatgcc ataattttcg
     2701 atggagaatt ttgtttttta taagaatatt gaataaatat aatcatttat ctatatgtat
     2761 agtataaaaa atgattgcat agtttcaatt ttcagtaaaa aatattattt tgaagaaaat
     2821 atattttata tgctagttta tataaaaaaa ataggaaata aaaaaattat cctattccta
     2881 ttaattccta ttatttatgt acaaaataaa ttataatttt agggtacttg aaaaataaaa
     2941 aaacctattg aaggagtact ttaatcctga atagatttct ttgtttgata aattataatt
     3001 ttatagacct ttatatttta atttattgta aaaatcttct cctttttgag ttattttact
     3061 tccatatctt cctgaactac aaattataag ttcttctttt tttagatatt caaatatttt
     3121 tttaattttt ccttctgtaa tttgaaggtt cttatcgagt agtgctttta aaattaatcc
     3181 cctaccaata ccaacatctg attccttatt taaaattagt atctctaata tattcaatat
     3241 atcattctta ctatatttta gttttaatga tgtatttttg ttatctgaag accttaagtt
     3301 tggaggtaaa tctttctcta atacaatatc ttcacacata atgtttaaat aggatgtaac
     3361 attttggagt tctcttatat tacctttcca catatagttt tgtataagtt tttttgcttc
     3421 tggtgtgatt actaatttct tattaattaa atcttccata ataattaata tgtcttcttt
     3481 tctttctctt agaggaggta tatttattgg aattgtattt aatcgataat ataaatcctc
     3541 tctaaattgg ctattatcaa tcatttgttc taaattctta tttgtagcag atatgattct
     3601 aacatctata ttaattacat tgtgagaccc aacaggcatt atctgcttct cttgaagaac
     3661 tctaagtagt tttgtttgta attctaaagg catatcgcct atttcatcta agaatattgt
     3721 tccattatta gcaagttcaa ataatccttg ttttccatct tttagacctc cagtaaaagt
     3781 tcccttgtca tatccgaata gctggctttc taataaattt tcaggaacgg ctgcacaatt
     3841 tactgctata aaaggttgat tttttctatt tgagttgtta tgtatagact gagctatgag
     3901 ttctttacca gttccacttt cacctctgat aagtatgctt aagtcagatt tagaaacctt
     3961 cttagctaaa tctatacatt caaacatttt aggactattt gtttttatat ccttaaatgt
     4021 atattttgct atttgtcctt tttctcttaa ttttttagtg agattttgtt ctaatttttt
     4081 tatgtatgtt atttcttgta aactataata tgtgcccatt ttttcatccc tattgtatat
     4141 gtttttttta tttacattta tatatttctt attgaatacg acaactttat ctagtatctc
     4201 tttctcactc aataaaactt ttaaactatc tacaaatata tcatcaatgt attttccata
     4261 tatatcctca tttatgtcta aaatatcttt tactttacta ttatatgtat ttatttcacc
     4321 atcttttgaa gtaaataata taccatcttt tgataaattc aatattgtat ctaattcttc
     4381 tatttttaaa aataattcct tatatttatc ttttatacca gtatctaaac ttattatttc
     4441 ttctgagtat ttaactagat tagattgtat ttcctttgaa tcaatttgta ataaatttat
     4501 tatttctata aatgtagaaa tatctatata tctgtgacct aaatcaaata tatctgagat
     4561 aaagctaggt actttttctg gaactcctgg agttatagct atttttatat ttttatagtt
     4621 attatcattc atatatggaa ttggtctaat attagtcact ccaattttat aaaataaact
     4681 tatagtttct agagtagttt catcagaatc atttacgatt agagcatttg taccctgtgg
     4741 taaagatagt agattataaa ttttatcttc cctaaaagtt cttcttacca caatcacttt
     4801 tttcttatct agtatattat ttataatttt gtctaatctt tctactgaca ttactaatat
     4861 cacatcatca tttataatat cattatcatt tatttcattt atgaagtatc tattaatatt
     4921 tatagaatct ccaaaaacta atttcaaatt attttctaaa aagtctatta aatcttttct
     4981 actatcattt accagagcta ctgatttttt catttatttc tccttatata ataaatagtt
     5041 tccaacaaaa tagttgtata aagcaatgta attttgataa tttaaattta tcaaataaaa
     5101 aagaaagtgt ctataatgac tttataaaag ttgcattaag acactttctt tcttataatt
     5161 aaaaatcttg tcaccaaatc cccctaattg ttgcttaaaa cttaaactgt atgtatattt
     5221 ttcatttcta ttcgattaaa ttataatata cacccaaaaa aatttatttt aataaattct
     5281 attgataata taattttgta aatatagaat tatattaaaa taaattatat atgaaaatat
     5341 atatgtataa gtttattctg cgtgagtaga atgaatttgt caagtttaat ttagttgtaa
     5401 ttgtatcttt tattaaaaat aatataaatt aaaacatata aataaaatat tttatacaat
     5461 atattgtaaa ggaggtaact ttgatgaaag cagaaaaaac aagtatatat ccaattatta
     5521 aaaataattt aaacaaaata tcaattgttg aatataaaaa gggtcaaaga tttgtagcat
     5581 cagataaaga cttacaagaa gtgttcttta taatagaggg agttgcatta gtggagtgta
     5641 ctactagagg aggaaataaa tttcttgttg acattgtacc tgaaaatgaa tttataggca
     5701 aaatcagtta catatatgaa cataatttga aatgtgatat atttgcaaag accaatataa
     5761 aattatttcg atttgaaaaa aatgtatttg aagagtttta tctcaaacca gattttattg
     5821 cactatttca cagaaaatgt acaagaagaa tatatgaatt atataaaacc agaatggtaa
     5881 gagaactatt ttcttgcaca gaagttattg cctattgtat atcaaataaa caagaaaata
     5941 atgtctgcaa tataaaagct attcgtaatt tcagtgaaat ctattcaatt agtagaaaaa
     6001 gtagatacca ttctctgcta aagttaactg aaaaggagat agtaaaaaaa atgggtaata
     6061 catatgaaat tttaaactat gatgaattac ataaattggc atttgaagta aaagagtttt
     6121 tggaagatga gtaaaaattg ttacttaatc aaaataaagt ataataattt ctgtaaaaaa
     6181 tagaaatagt ctcactgaaa atcaaaaata ctttagttat tttcaatgag actgtttaga
     6241 aatattgtat acttataatg tatagtataa ttattaatca atttccttta ctatattaat
     6301 agcccatttt ttagataatg ctctaggaac accaaatata aacttaacca cttcttcact
     6361 ataagtgagt aaaacgagta caaatatagg tgcaccttta aatgcagcta taaaagttag
     6421 aggaatagaa gctaaccaca tacatcctaa ttctagaaat agagcatatt tagtatctcc
     6481 tccacttctt aaaataccaa ttataaccaa tgtattaaaa gatttaagag ccattagtat
     6541 tcccatgata aagaatatct tagttatatc agaagctaag ctatcagaaa cactaaacat
     6601 ttttaataat aatggtatat ttaaaattaa aataattcca agtattaaac cagctgaaaa
     6661 tacaagtata gaaaactttt tagcatattc aatggctctt ttaatatggt cagctccaag
     6721 ttcatttcca agcataatag atgcaccaga tgcaatacat acagctgtca ttatgaagaa
     6781 attacctgta ctggttgcta tctggctagc tgctatagca gaagtaccag ctcttgcata
     6841 tgcaacagaa tacaggacag ttccaattgc ccatacagag tcatttacaa atataggaaa
     6901 gctttttgat gaaaaagatt ttataaaaat tttatcaata gcttttagat tttttagacc
     6961 aaactttaat atatagtctt ttttataaag gtaaacataa gtaatcatta aaattaattc
     7021 acatattcta gcaataacag tagctagagc agcacctttt acacccaatg cgggaagacc
     7081 gaagttacca aatataaatc cataatttaa aataacattt gttacaagtg caaatgcact
     7141 acaaatcata cctaacttag gatttctaac acctcttgaa ccagtactaa atacagtact
     7201 tacagcaatt aatggataac taaatactgc aatactaaag taatctatac aaagttttac
     7261 cacctcagaa tcatacgaaa atatgtgtat aattggcttt ggtgttagta aagcaggaat
     7321 aacaaataca aaacttaaaa caattgccaa tacacaagta agacctgtga cttttcttat
     7381 attactcaca tccttctttc cataaaactg tgaaataaaa actccagcac ctcctgtgat
     7441 accagataag gacatattaa aaagaaagaa aaattggttt gcaactccaa ctgaagctac
     7501 agatgtctcc cccaaactac ttatcataat tgtatctatt acatttacag aagtagaaat
     7561 taagttctgt atgataatag gtatacataa agatagaagt attttataaa atcttttatt
     7621 ttcgtctttt aaagaaaata gttcttgcaa ataatcctct cctttttaca taaattcttc
     7681 ccactcatca tatagagagg caaggttatt ttctaaatta attttttctt ggctaacttc
     7741 tttagcttta tctggattag agtatacttc ttcttgacat aaaagtatat ctaatttttc
     7801 aatttcaatc tctaactttt caatttcttt ttctatattt tgtcttttta ttctattttt
     7861 cttttctatt tctctttgtt ctctctcttt tcttttttca tcttttattt gagttctagt
     7921 tttttcttct ttttcttcta taatactcat ctcttggatt tgcctttttt tatctatata
     7981 ataatcataa tttcccagat attcagtaat tccattttca tctaaaacta aaattttatc
     8041 aacaacagta tttagaaagt atctatcatg tgatattgta aatatagtcc catcataatt
     8101 agttaatgcc tcttcaagga cttccttaga atcaatatct aggtgattag taggctcatc
     8161 taataacaat aagtttgcat ttgatagtat aagtttaagt atggcaactc tagctctttc
     8221 tccaccactc aatgtagaaa tcttcttaaa aacttcttca tctacaaata aaaatgcccc
     8281 taacatattt ctcaaagtag tttgagtaag atgagtatta ttttcccaaa tctcatcaat
     8341 tattgtgtta tctaaattaa gagttttttg ttcctgatgg aagtaggaaa catgtacatt
     8401 agttccaaat ttaatattgc cactaagagg ttgtagttca ttagttatta ttttaaataa
     8461 tgtagatttg ccaacaccat ttgcacctat aagtgcaact ttttcccctc tatatatatc
     8521 taaatccaag tctttaaaaa gtattctttc tccataaccc atagatacat ctctaatttg
     8581 aagaacatca ttaccactct ggacagaagg cgtaaattgt atacgagctt ttttcctata
     8641 agcttctggt ttatctaaaa cgtctacctt gtctaatgct ttttctttac ttcttgcacg
     8701 ctttaggtgt ttttctctac cataagcttt tagtctttca attgattctt cttgcttttt
     8761 tatttctttt tgttggtctt caaatttctt aagctctagt tctttttcta ttttagataa
     8821 ctcaacaaat ttagagtagt taccattata tactttaagt tttttgttgt gaacttcaaa
     8881 aattctattt acggattggt ctaagaaata tctatcatga gatattaaca tgacagttcc
     8941 tttatattgt tttaaaaata cttctaacca ttctattgct tcagagtcta agtggttagt
     9001 aggttcatca agtaacaata gagttggttt cttaagaagt aattttccta aaagaactct
     9061 agttttttca ccaccagaaa gtatgcttat tggcttatcc atatcattgt cactaaatcc
     9121 taatcctttt agaactcctt tggcttcaga tttatatcca tatccattta aatctgaaaa
     9181 taattctagt ttatgtgaat attcatccat gattttttct ataattggag agtttgtttt
     9241 tgtactttct tcagatattt taacctccaa ttctcttaaa taggattcca tttctatcaa
     9301 atttttaaaa acttctagca cttcttccaa aatagtatta tccgaataaa aattggtatt
     9361 ttgttctaaa tatccgattt cacaatcttt agaagtataa atatctccac tatcatatcc
     9421 ataaattcct gaaattattt taaataaagt agtttttcca gtaccattaa caccgattat
     9481 accaatttta tcgccttcat ttactgtaaa actaatattt tctaatatag aatctatacc
     9541 aaaactttta tttaagttat tacatgacaa aacaatcata aatttctacc tccttgaact
     9601 atctaaaatt ataatgtttt gatataatat aatcaaggtt atatgtatta gttttgaaaa
     9661 agaaatattt tattgtgaat caaacaaaaa agaggacact tttaggaggt gaagatgttg
     9721 ggaaataaaa atatatcaat ggcagttata agaaggctcc caaaatatca tagatatctt
     9781 ggagacttat tagataggga tatacaaaga atatcttcta aagaattgag tgatataata
     9841 gggtttaccg cttctcaaat aagacaagat ttaaacaact ttggtggatt tggacaacaa
     9901 ggatatggtt ataatgtaga agctcttcat actgagatag gtaaaattct tgggttggat
     9961 cgaccataca acgcagttct tgtaggagca ggtaacttag gacaagctat agccaattat
    10021 gcaggattta gaaaagctgg attcgagata aaagctttat ttgatgcaaa tcctagaatg
    10081 ataggtttaa agataagaga gtttgaagta ttagattcag atactttaga agactttata
    10141 aaaaacaata atatagatat tgctgtatta tgtataccta aaaatggagc acaagaagtt
    10201 attaatagag ttgtaaaagc tggaatcaaa ggtgtatgga attttgcacc tttagattta
    10261 gaagttccga aaggtgttat agttgaaaat gtaaacttaa cagaaagttt atttacctta
    10321 tcgtatttaa tgaaagaagg aaagtagaca acttaaacat attaataatg agcagttgtg
    10381 aagagtattg agaaagtcag aagatttaat attaaatcct ctggcttttt gaaatattag
    10441 gataaaaatt taaataatgt atggaaataa acaatattaa ggagagtggt ttttgtggag
    10501 gaattatgga aaaaggcaat tgaatttcat ggtcatgaat gtccagggtt agctatagga
    10561 tttaaagcag cacttgcagc aagaaaatat ttaggatgta aacagtcagg agatgaggaa
    10621 attgtatgta tttctgaaaa tgatgcttgt ggaatagatg gtatacaagt cgtgctaagt
    10681 tgcacaatgg gtaaaggaaa tttactactt aggatgactg ggaaatcagt atatcatttc
    10741 tttaataggg aaaatggaaa atctataaga atatatgtaa agtcaaagcc atttcaaatg
    10801 gatagagaag gatacaaaaa gtacttatta gaaagtgatt ttgaagaaat atttgagatt
    10861 acagatacta agttaagact tcctgaaaaa gcaagaatat ttaaatctct taaatgtgaa
    10921 gtgtgtggtg aatttgcatc tgagcaatat ataaggattg aagaaggaaa gaaagtatgt
    10981 cttgattgct ttaataaata tgaaagattt tatgaggagt attaaaatta taaattagat
    11041 taaagttaaa agtattagat atgtactaac agtattttaa gatgaattag gtagcaacat
    11101 aataaaatat ataaataata ttacttgaac catacataat taaaaagagg ctgattagta
    11161 tttagaaaat aaaatcagtc tctttatgaa taacgaatta ttattctggt tgaggtgcat
    11221 ctacaggaca agctcctgca caagaaccac agtctataca agaaccagca tctataacat
    11281 atgcgtcgtc tccagctgat atacagctaa cagggcattc agcctcacaa gcaccacagc
    11341 ttatacaagc gtcagtaatt ttatatgcca ttttgaaatc ctccctttta tatgtattgt
    11401 aattcaataa cattataaca aatattattg aatataacaa ttaaattaat tctacaacaa
    11461 aaactttatt atgatattct tgttttaaag ttttacaata aagtttaatc tgcttatatt
    11521 tttatttatt ttaaagaagt ttattttaaa aataaaatta aatttaaaaa gttatgtatt
    11581 gattatattt aaaaatgtta tactctaaaa aagtatattt tattttaaaa tttattaata
    11641 caaaggagat ttactatgaa aaataaatta gtttacatat gtattatgag tctattgcta
    11701 tttgtagtag gatgttctaa taatccaaat aaggaaagta ccattaaaaa agactctaag
    11761 aataaccaaa gccaagttaa agaagaaaaa agagaacctg tgaaaaaaga tataactata
    11821 agtttcgctg gtgatgtaac tatggggaac tataaaggtt catcatatta tggcagtttt
    11881 gaccatgaat ttaaaagaca aggagaagat tacaattatt ttcttaaaaa tgtaaaacct
    11941 gtatttgaaa aagatgactt aacagtggtt aatttagaag gtccacttac tacagcgtca
    12001 aatgcaaaag aaaaaaaatt tgcatttaaa ggaaagcctg gatatgtaaa tattttaaaa
    12061 tctggaagta tagaggcagt aagtattgca aataatcatt cagaagatta ttttgaagaa
    12121 ggaatgaaag atacacagtt tatattggat gagaataaaa taaattattt tggattaggg
    12181 aaagatgctg ttgtagatgt caaaggaatt aaagtgggtc tattagggta taatggatta
    12241 tcaactgaat ataatgaaaa aaatttaaaa caaatggaag atgatattaa gtccttaaaa
    12301 aagaaatcgg atgttgttgt agtgtacttt cattggggga tagaattaga ttattatcca
    12361 gataaaaaac aaaaagattt tgctcattat gctatagaca agggagcaga tttagttatg
    12421 gggtctcacc cacatgttat tcaaggaata gaaaagtata aaaataagta tatagcttat
    12481 agtctaggga atttttgctt tggaggaaat aagaatcctt ctgatacaga tagttatata
    12541 tatcaacaaa cctttacttt ttcagataat aaattaactt caattaaaga gccaaatata
    12601 ataccaacct caataacatc tagtagctcc agaaataatt atcaaccaaa agtattggat
    12661 ggaagtgaga aggatagagt tttaaataaa cttgaaaaaa taagcaaaga tttaaataaa
    12721 taaaatgtaa aaaaaaataa atatatatat ttattttaat aatttatatt ttgtttaggg
    12781 tatggtaaat cgtggtatta aataagtaga ttttaatagt taaattatag tcaattataa
    12841 taaagctatt taatctactt ttttaatata aaaatataag ggggaatttg taatggcttg
    12901 taacacttgt aaaatgtgcg aaagtgcaga caagaaatta gaaagttttg tagcttcaaa
    12961 ggatgttgaa acagcatttc atagaacaga agatcagaaa gttaagtgtg gttttggact
    13021 tcagggggtt tgttgtagac tctgttcaaa tggaccatgt agagtaactc ctaaatcacc
    13081 aagaggtata tgtggagcag atgcagacac tatagtagca agaaactttt taagagcagt
    13141 agcatcagga gcagcttgtt atttacatgt ggtagaaaat acagctaaga atttaaaaaa
    13201 tgttggaata actaaaggtg ttgttaaagg agaaaaaaca ttaaatcaat tagcagagat
    13261 gtttggaata gaaagtgatg aaaagtatga taaatgtata aaggttgcag acaaagttat
    13321 caacgatttg tataaatcaa gagatgataa aatggaatta gtagaaaaaa tagcttatgc
    13381 acctagagtg aaaaagtgga aagagttagg tataatgcct ggtggtgcaa agtcagaagt
    13441 ttttgatgca atagtaaaat catcaacaaa tttaaatagt gatccagtag acatgctagt
    13501 taattgtttg aacttaggta tatcaacagg attatatggt cttacactaa ctaatctttt
    13561 aaatgatgtt atgttgggag aaccagttat aagaatggct cctgtaggat ttaatgtaat
    13621 agacccagac tacataaata taatgataac aggccatcaa cattcaacat ttgcaaattt
    13681 ccaagataga ttaaaagatg aagatgttat aaaattagct caatctgttg gtgcaaaagg
    13741 ctttaagcta gtaggatgta catgtgttgg tcaagattta caattaagag gagaacatta
    13801 tcaagaagta tttgctggac atgcaggtaa caattttaca agtgaggctg ttttatcaac
    13861 tggagcaata gatatagttc tttcagaatt taactgtact ataccagggc ttgaaccaat
    13921 agcagataaa tataaagtaa aaatggtttg tttagatgat gttgctaaaa aagcgaatgc
    13981 agaatacata ggtttagaca gaagtaaatt agatgaactt agtaacactt taatagaaaa
    14041 agcattggag tcttataagg agagaagagg aagtattgag atagatatac caaaagacca
    14101 tggatttgaa caatctttaa ctggtgtaag tgaaaagaac ctgaaagcgt ttttgggaga
    14161 ttcatggaaa cctcttatta atttaattgc agaaggaaaa attaaaggtg ttgcagctgt
    14221 tgtaggatgt tcaaatatga cagcaggagg acatgatgta aatactgttg aacttactaa
    14281 agaattgatt aaaaaagata taatagtact atctgcagga tgttctactg gaggattaga
    14341 aaatgttggt cttatgtcac ctggagcaga agaattagca ggagaaaact taaaagaagt
    14401 atgtaagact ttaggaatac caccagtatt aaactttgga ccatgtctag ctataggaag
    14461 actagaaata gtagcaacag aattagcagc tgaacttgga attgacctac cacaattacc
    14521 attagtgctt tcagctccac aatggttgga agaacaagca ttagctgatg gagcgtttgg
    14581 tcttgccctt ggcttacctc ttcatttagc tttacctcca tttataacag gaggaaaatt
    14641 ggtgacagaa gtattaacag aaaaattaaa agacttaaca ggaggacatg ttatagtgaa
    14701 tccagaccct aaatcttcag ctaatcaatt agaagaaata ataatagata gaagaaaaaa
    14761 tttagggtta aaggatgtgg aatgcaatgc atagaatttt tataaataaa gatttatgta
    14821 caggatgtaa gagctgtgta ctagcatgta tgctaaaaca caataaagat tatgacatgt
    14881 acactcttga tttagaaaat atagataatg atagtagagg gcatatagaa ttagatagta
    14941 aacataataa tccagttcca attctttgta gacactgtga tgaacctgaa tgtgtattag
    15001 catgtatgag tggtgcaatg cataaagata gtgaaagtgg aatcgtttca tatgatgaag
    15061 agaaatgtgg ttcatgttat atgtgtgtaa tgtcttgtcc atatggatta ttaaagccag
    15121 atgatagaag caagcaaaac atacttaaat gtgatttatg taaagatgag gagtatccta
    15181 gatgtgtagc taattgccca agtggagcaa ttgaattaca gaaggaggaa aatgatgaat
    15241 tatgtagtgt taggggctag tgcagctggt ataaatgcag taaaaacatt aagagaatta
    15301 gataaagatt caaatatagt agtaatttct aaagatgaaa acgtatattc aagatgtatg
    15361 ttgcatcacg ttatatctga acacagaact ttaaaacaaa taaattttgt tgatgaagat
    15421 tttatggagc aaaataatgt aaaatggatt gcaggtaaga ctgttaaagg tatagacata
    15481 aataaaaagg tagttcaaac agaagacatt actgtaaatt atgataaact tttaatagct
    15541 acaggtgcat cttctgctat tcctcctata aaaaatttaa gagatggaaa ttttgtatat
    15601 tctgtgagaa acatagatga tatttataaa ataaaagaaa aagcacaaaa ttctaaaaat
    15661 gtagttataa taggtgctgg tttagttggt atagatgcat tagtgggatt atttaaatat
    15721 gagcagttaa atatttctgt agcttttatg gaaaagtaca ttttagatag acaattggat
    15781 gaatatacag catcagtgta tgaaaataag ttcaaagaaa aaggtgtaaa attttaccca
    15841 agtgcatcaa tacaagaaat tgtattggat aacagtaaaa atgttacagg tgttgcattt
    15901 tcaaatggtg aagttttaga tgcagacatg gtaattgtag ctacaggggt taaaccaaat
    15961 gctgactttt tagatgggac aggaatagaa tatgatagag gtataataat agatgatatg
    16021 tgccaaacaa cacaaaaaga catatatgca gcaggagatg ttgtaggtaa aaatgctatt
    16081 tggcctctgg cagtaaagca aggaattgta gctgcctata atatggttgg aaaagataag
    16141 aagatagaag atgaatttgc ttttaaaaat agtatgaatt tcatggatat accaactatt
    16201 tctataggaa tgaatacacc tgtagatgat agctataaag tattaaccag acatggaatt
    16261 aatgattata agaagtttgt ttttaaagat aatgtaatct acggagcagt tatacaagga
    16321 gatatttcat atgtaggtgt attaacttat ttaataaaaa ataaagttga aatatatgat
    16381 ttagaaaata ggatatttga tgtatgttat gcagactttt ttaatataaa agaaaatgga
    16441 gaattttgtt atagtgtata gtatatacgt ggagtaaggt ttataaatac agtaaatcaa
    16501 taaatagagt tattctaaaa taagaaaaat gacaaatctt atttagaaat agctctattt
    16561 tttgtaatta aatttaaatt atattcaatt tgtaaaatat tattttgaac aattatacat
    16621 atactctcta gttagaggta aatcattttt tataccttta gtgaaaagta tttgatgtat
    16681 atctataata ccagtgttga aagcagcagc acaagaacaa aggtataaat cccacattct
    16741 tataaactta tcatcaaaca tttctttaat ctttggaaga ttctcagaga aacttttttg
    16801 ccagtatagt aaggttttta cataatgtaa tcttaaactt tctacgtcta tagtatgata
    16861 tttgtaatca ctacaaatat gtatcatttc tcttaggcta ggaataactc ctcctgggaa
    16921 aatatatttt tttatccaag ggtctccata agattcctgc aatccactta tatagtgaag
    16981 taaaaacaat ccaccatctt ttaaaacagc atttacgttt ttaatgaaaa gttcatagtt
    17041 ttctctacca acatgttcaa gcattccaac gcttacaact ctatcaaaca taaggtctga
    17101 tttttttaat tctctatagt ccataagtct tacctcaaga tagtcttgaa ggttctcttc
    17161 tttaattctt gcgttaaatt ccttaaattg ctcttcgcta agtgtaattc caacgccgtg
    17221 aattttatat ttttttgcag cttctattag taaaaatccc caaccacaac caatatcgag
    17281 aaggctcata ccttcctcta aatttagttt agttaatatg tggtgaactt tattgacttg
    17341 agcatcataa agagtatcat tatcatttct aaagtatgca caagaataac taagtgtctt
    17401 atctaaccat aagctataaa aatcgttgcc aatgtcatag tgggcatgta tttctttctt
    17461 ctgatgtctc attgaatttg atgagtgcaa tagatgtttt acagctgaat tatcaatatt
    17521 gaatttgtct atttgtttta aaagtagatt taaagttaag aataaatctc cctcaacttc
    17581 aatgtctcta tttatgtagg cttctccaag tgctaaagat gtacttttta atagttcaga
    17641 cttgctaata tcattattta ctataacttt gaactgaggg gagccctctc caattagaaa
    17701 ttcttcctca tctttaagcc taactagaaa tggtgtttca ccaaatttct ctaaatagtc
    17761 ttttaaaaaa ttttttgtaa tattcatatt accagctcct tctaatgtaa atccagtaag
    17821 tttccctgct taaaatatat tatagtcctt tttttaaaaa agtaaaattt tttcaataaa
    17881 ttttttattt aaaggaaatt tattttttat aaagaaattt catgttgtag tatatttttt
    17941 gcttataaat tttggtactg gatataatat taaactgtta atgatataat aaatttaatc
    18001 tataaagtaa ataaaatttt gtaataaata gttaaagcta ttttataagg agatatatga
    18061 tggaagtata tgctttggtt gggtcaagtg gcacagggaa gagctttaag gctttagagt
    18121 tcgcatatga aaatgatata gaatatataa tcgatgatgg gattttaata tacaaaaaca
    18181 aggttttagc tgggatatcg gcaaaacaag caaatactac tatagaagca gttaaaaggg
    18241 ctatttttta taatctggag catagacaag aagttagaga agcaattaaa aaagaaaata
    18301 taagaaaaat tcttattatt gggacatcaa aaaaaatggt taatcaaatt gtagagagat
    18361 tgtcaattgg aagggtctgt aagtttataa atatacaaga tataagtact aaatatgaaa
    18421 tagaaatagc aaaacaagct agaaaagaag gaaatcatgt aattcctgtt ccagccgttg
    18481 agataaaaag tatggcaagt ggtctcagta taaattcttt gaagagactt tttagaaaag
    18541 gaaataatag gaatatggta gttttagaaa aaacaattat aagaccaact tttagttata
    18601 taggaaagtt ttatattagt gctgatgtaa ttaaacagat tattgaatat gaagtataca
    18661 actttggaag cattgataga ataaataaaa tcaatataga gaattgcaat aattttatga
    18721 atatttttgt aagtataaat atcaatgatt tagaaactat aaaaaaaatt gaagacatac
    18781 aacagacaat aaaaaagtct attgagaaaa tgactttagt taatgtacaa aaaatagata
    18841 ttaacattca taaaattaaa aaaataaact tcctccaatg ttaaaaaata aactgagaaa
    18901 atgatatact aatttgcaat aaagtgtgct ataattaaac tgtaaattta ggaaatggtt
    18961 ttttctaaat ggagtataca taattataac gtatttataa gggggctttc aaatgtcagg
    19021 aaaagatgta aatgtcttcg agatggcgca atctcaagta aaaaatgcat gtgataaatt
    19081 aggtatggaa ccagcagttt atgaattatt aaaagaacct atgagagtta tagaggtttc
    19141 aattccagta aaaatggatg atggttctat aaaaactttt aaaggattta gatcacaaca
    19201 taatgatgca gtagggccaa caaaaggtgg aataagattc catcaaaatg tttcaagaga
    19261 cgaagtaaaa gctttatcta tatggatgac tttcaagtgt tctgtaacag gtataccata
    19321 tggtggaggt aaaggtggaa taatagtaga tccatcaact ttatctcaag gtgaattaga
    19381 aagattaagt agaggataca tagatggaat atataaatta ataggtgaaa aagttgacgt
    19441 tcctgcacca gacgtaaata ctaatggtca aataatgtct tggatggttg atgagtacaa
    19501 taaattaact ggacaaagtt ctataggtgt tataactggt aagccagttg aatttggtgg
    19561 ttctttagga agaacagctg ctactggatt tggtgttgct gttactgcaa gagaagctgc
    19621 tgctaaatta ggaatagaca tgaaaaaagc taaaatagct gttcaaggta taggaaacgt
    19681 tggttcttat acagttctta actgtgaaaa acttggtggt actgttgtag ctatggctga
    19741 atggtgtaaa tcagaaggtt cttatgctat atacaatgaa aatggtttag atggtcaagc
    19801 tatgttagat tatatgaaag aacatggtaa cttattaaac ttcccaggag ctaagagaat
    19861 atctttagaa gagttctggg cttcagatgt tgatatagta ataccagctg cattagaaaa
    19921 ctctataact aaagaagttg ctgaatctat aaaagctaaa ttagtttgtg aggctgctaa
    19981 tggaccaact actccagagg ctgacgaagt atttgctgaa agaggaatag ttcttactcc
    20041 agatatatta actaatgctg gtggagttac agtttcttac ttcgagtggg tacaaaactt
    20101 atatggatac tactggtcag aagaagaagt agagcaaaaa gaagaaatag ctatggttaa
    20161 agcatttgaa tctatttgga aaatcaaaga agagtacaat gttacaatga gagaagctgc
    20221 ttacatgcat tcaattaaga aagttgctga agctatgaaa ttaagaggat ggtactaaga
    20281 tttactctta ataaataata ggatataatt atttaagata taaaggggct gtacatagta
    20341 cagcccttaa attatgtggc ttacaatgaa gtaagctatt tttgttttaa cttataaata
    20401 acttgataaa ttatgtaatt tagaatgcat aaataagatg ggtgaaaatt aatggttgat
    20461 ttaattttga atgtattttt taccaccaca tgattacaaa ttagaggagt tagattggat
    20521 ttttggacat gaacttatgt attttaaaag caaagacctt catttaaagt atctagtatt
    20581 atttttaaaa atagtatatt ggtttaatcc atttatatat ataatggaaa aatatatgga
    20641 tttggattgt gaactttatt gtgatgagag agttttaaaa aattgtactg tacaacaaaa
    20701 gcaagaatat gctctaacta ttgtaaattc aatgaaaaga ggtataaatt tttcaaataa
    20761 atttgtaact ggattaaata aacaatctga tattagaaaa agagtaatga acatgttcag
    20821 tgaaaaacat aaaaatggta tcttaatggc tttgattata agcttgtttt cttctattac
    20881 attttttaaa ttcgattcaa ctagtcttat tgaagagaat gatttcttag agaggtcaag
    20941 atatgcgttt gaaggaaggc aagaagacat gtttgtaaca atagattcta catatgcaga
    21001 tgcacctata aaacttagaa aagagcatga agaaaactgt agagtcaatg gaatagtacc
    21061 aaaagattca gattcaatag aaattattcc tagattttat aaagattgta tggatttaaa
    21121 aaaataagtt agacttaata ttgatgttga tattatgaat tttttatatt taagcaattg
    21181 aaaattttat tatagattca attttatatg tgtttaagta tgaaatttat agatagttga
    21241 aataattaaa tatgattgat gcataggaat cattactaag ctataattaa ttatagggga
    21301 gtttaaataa attatgagtt acacaattat aaaatgataa aaaatagtta tctgttacaa
    21361 aaaatgtatc tttttaatta ataaagataa tatgaaaact taaaaggcaa ataaacttaa
    21421 acataaaata ctcttaaata agataggaga aaaatgtatg tctaacttta ttctaaatgg
    21481 gatttttaga acagttatag taagtagtct aagcattctt ctgatattga ttttcaagaa
    21541 aaatgtattt aaaagattta gcaaaaaatt taattattat atatggatga tagttgttat
    21601 taaattattt ttaccattta catattatac ttttacaata aatatcttga gaagtaaaaa
    21661 acacattaat attaataaca taaatttaga gggatttaat aatgtttcaa ctataagtaa
    21721 taatattata ttgtacactt ggattataac tgtagtagtg tatttaattt acactatatt
    21781 taaatatata aaacttaaaa atttaataaa tgacttatct tatgatgttg atgatagaga
    21841 gattgtaaat ctttataaaa atatattaga agaatttaat ataacaaaag atataaaact
    21901 caaatactct tatgaagttg aaacaccagc attttttaat tcatgtgtac ttttgccacc
    21961 acatgagtat aaattgaaag agttagactg gatttttaga catgagctta tgcattttaa
    22021 gagtagggac ctttatttaa aatatgtaat cctgttttta aaaacagtat attggtttaa
    22081 tccatttata tatataatgg ataaacatat agatttagat tgtgaacttt attgtgatga
    22141 aagagtttta aaaaatcgaa attcagagga aaaaaaggat tatgctttaa caattctaaa
    22201 tgcaatgaga aaaggttcaa atacttcaaa taaatttata gctggactcc ataagcaatc
    22261 tgatattaaa aagagagtta tgaatatgtt taatgaaaag tacaagaatg gtatattaat
    22321 ggcattaact ttatgtttat tatcttctat tacttttttg aaggttaatt caacgagtat
    22381 tgttaatctt aatgtattac ctaaaggatt tgaagactta cgaactgtta gcagtatacg
    22441 tttttcagtt ataggattta catatgcaga tgctcctaaa aatatgaggg aagaatataa
    22501 aataaattgt gaatcattag gtttgatacc taaagactct gataaaatag aagttggtgt
    22561 agaatattat gacagtctat tgaatgatta aataaatatt attttaacag atattaatta
    22621 taaagttttg aatagtaatt tgttgagaaa taaatatatc cttataaaaa tagatactta
    22681 tataccaaga ataaaaaata gttaagatag tacacaagga tatacttata aagaacttaa
    22741 ataagtgaaa taaattatta attataaggt ttataatttt aaaaaattag ataaattcag
    22801 gtgtaaaata ctataaaaca caattcggaa aagtgtatgt tgaacttcat ttaaaataga
    22861 attttcaaag ttgttatagt aagtagttta agcattcttc ttatattaat ctttgagaat
    22921 aatgtactta aaaaagttag taaaaaattt aactattgta tattaatgat agttgctatt
    22981 gatatattat ctaaaaaaat taagtatgaa aagattactg ctaggacaat cttttcatac
    23041 ttaatttttt aatatttata ttctccaaaa ttttcatctt tttaacttag aattattaga
    23101 atttgagaat cactattagg aaataggttt tgatttatgc agggttaaaa atttcacaga
    23161 atatctaact ttatactaaa tccatcaaaa aatatacgcc atataaaagc gcataaaaaa
    23221 acacataaaa caatatttat gcgcacttta acctcgaatg gtacaaaatt ctttactttt
    23281 acagacccat attatataat taagtaaata atgtatattt aggtgacata ttggataagc
    23341 taatttattt attttattaa tataatgata ctataaaagt tatataaagt ggtttacaaa
    23401 aaagttacag atagagcttt tattaatgta ttgtgtatta gtattttatc cttaggtaca
    23461 cttcacctac aaaatagaat cataagataa ttatgggaaa attttaggag gtttatcgtg
    23521 aagaaaaaga tattaatacc agtatttgca tcagttatgg cattatcagt aagttcaatt
    23581 gtaaatgcag atgaagtaaa tgattcatct caaaataagg atgataaaac aaatactgaa
    23641 ttaaatttag gtgaatataa agaagtaaaa tataaagttg caaaaataaa agatggagta
    23701 gctataaaga taagagaaga aggtcaagtt caaaacatag cttattctgg agatgaattt
    23761 acggttttag gaactcaagg agaatgggtt aaggttaaag ttgaagatgg cgaaggttgg
    23821 ttagctacta gatatgtaga tatatctgaa ggtgtaggat atactaacgc tgataaagta
    23881 aacttaagaa aagataagag tgaaagttca gaagtaattg aagagctgga aaaaggaagt
    23941 tctttattgg ttttggagga taatggagat tggttaaaag ttaaagatgg ggaaacagaa
    24001 ggatatgtaa aatcatctta tatatctgat aaagctcctg taatagaaga gccacaagta
    24061 aacccaagta ttgaccaaaa tgtagattct acaaataata atcaacaaaa caatgcaaat
    24121 actaatcaac aaaataataa ttcaaatgtg ccaacagcta actctaatgc agttcaagct
    24181 gtacttaact tggcatattc taagcaaggt tgtccatatg tttggggagc agaaggacca
    24241 aacacttttg actgttctgg atttacacaa tatgtgtata gaaatgcagt aggaaagaat
    24301 ataccaagaa catctaaagc acaatctaaa tatggacaaa ctgtaagtaa agcaaattta
    24361 caaccaggag acttagtatt cttcacaact aatggttctg gttctgttag tcatgttgga
    24421 atatatgtag gtgggggtaa tatgatacat tcaccatcaa caggaaaaac agttagtgta
    24481 actagtataa attcatcata ctatacagca agatttgtta cagcaaaaag aatattataa
    24541 tcggtttgta atatgacaaa ttgataaata cataaatata tataaacgct ctatattata
    24601 tttaatttaa tcatggaaac aaaaaatgat tatattttaa atgtactata gagcgttttt
    24661 gtatcacttt aaatctaatc aagattcaag ttaatatgac tattaaatag gagccttttc
    24721 atatgatgat tatttgcgca atcccttgac aggatagggt aaaggtggta agctactaac
    24781 agtacaaaaa tacttttaat tttagttcag agaggctaaa aaaggaggac gaaagatgtt
    24841 aaaatcaaga aatttaatcc aaccagaaga cttttcaata gaagaaatag atgaaatatt
    24901 agaattagct caaaaaataa ttgacaatcc gtcaaaatat tctcgtatat gtgaaggaaa
    24961 actattagct acattatttt atgaaccatc aacaagaaca agattaagct ttgaatctgc
    25021 tatgaacaga ttaggaggac gtgtagtagg cttttcagag ccaaattcat cctctgcatc
    25081 aaaaggtgaa actctaggag atacaatgag gatagtatct ggttatgttg atataatagc
    25141 tatgagacat cctcaatcag gtgcagcttc agaagcagct agatatacgg aagtgccatt
    25201 tataaatgca ggagacggca aaaaccagca tccaactcaa acacttacag acttacttac
    25261 tataaaatca ttaaaaggaa ctttagaaag ccatacaata ggattatgtg gtgatttaaa
    25321 atatggaaga actgtgcatt ctttggttaa ggctatggca agatataaaa atacaaagtt
    25381 tgtatttata gcgcctgaag agttaaaaat gccagattat ataaaagaag ctataaaggg
    25441 acatgcatat tatgaaacta ataatttgga tgatgttata ggaagcttgg atgttttata
    25501 tatgactaga gttcaacaag aaaggtttga agataaatca gagtatgaaa gacttaaaaa
    25561 ctattatatt ttaaataaag ctaaattaga aaaggcatct aaagatatgt tagtaatgca
    25621 tccattacca agagtaaatg aaatagacat agatgtagat agtgatgata gagctgtata
    25681 ttttaaacaa gctaaatatg gaatgtatgt tagaatggct ttaataataa aacttttagg
    25741 tataaatgaa gactaatagt tatcatataa tagtaaaaca aaggagattt tgggatgtat
    25801 aaaattctgg aaaatatata tataggcgaa gatatgtata gaatgaaagt aaaaggtaat
    25861 tttgaaggta aaatgggaca attctatatg ttaagagcat gggatactta tccagtactt
    25921 tcaagaccta taagtataca tgatatagat gaagaaggga taacttttct ttataaagta
    25981 gtaggagaag gaactcaaat tttgagtaac ctaaaggtaa atgataatat aaaattagaa
    26041 ggcccttatg gtaatggata tgctaaggtt gatggaaagg tagctctagt aggaggagga
    26101 atcggtgtag ctccactata tttggttgct aaaaatataa aaaattgtga tgcatatctt
    26161 gggtttagag aagatgttat attagaagat gaatataagc aagtatgtaa taaagtctat
    26221 acaacagtag gaaatacttt tgtaacagat ataattgatg ttgagaaata tgattatata
    26281 ttaacatgtg gtccaactcc aatgatggaa aaattagtta agatggtaga aggtactaaa
    26341 acgagaatta tggtatctct tgaaaaccat atggcttgtg gagtaggtgc ctgtttagta
    26401 tgtacgtgta aaactaatgg aggaaacaaa aagacttgta aagatggtcc agtgttctgg
    26461 ggagaggacg tgatttttaa tgggtaattt aagtgtgaaa tttggaagtg tagaatttaa
    26521 aaatccagta ataatggcgt ctggaacttt tggatttgga aaagaatata atgagattta
    26581 tgatatacaa aaacttggtg gtataagtag caagggtctt actttaaata aaaaacctgg
    26641 taacaatggt atgagagttc atgagacacc atccggtatg atgaatagtg ttgggcttga
    26701 aaaccctgga gttcaaggat ttatagacta tgaattacct ttttttagta aactagactt
    26761 agtcagaata gctaatgttg gaggtgggac attagaagac tacttattag gggttcaaat
    26821 gttaaatgac aagcctatag acattattga attaaatata tcttgcccaa atgtcaaagc
    26881 tggtggaatg gcttttggta taaaaaatga agtggcaaga gaagttgttc gtgaggtaag
    26941 aaacataacg aaactgcctt tagtaataaa attatcaccc aatgcagaag atattgtagg
    27001 aatggcaaaa gtttgtgaag aagaaggtgc tgatggagtt tcattagtta atacttttaa
    27061 agcaatggca attgatataa aaaatagaag accagtattt gaaaatgtat atgctggatt
    27121 atctggacca gctataaaac ctatagcttt gagaatggta catgaagtgt gtaaaaatgt
    27181 aaatatacct gtaatgggaa tgggcggaat aactaaagcc acagatgcta tagagtttat
    27241 aatggcagga gctacttgta tccaagttgg aactgcaaat tttatgaatc ctagaatagg
    27301 tattgaaata atagatggga ttaatgaatt tatggataga gaaggaataa aaagtttaga
    27361 cgaaataaga ggaattatat aaggtagaat aaatagtatt ttaaagataa aaaatataga
    27421 ttaaataaac aataatttta taacattaac atggaggaaa aataatatga gtaaagtaga
    27481 tgtagtggat atattaaaga aaagtgatgc attgttggag ggacattttt tattatcttc
    27541 aggaaaacac agtaatagat acgtacaatg tgcaaaagta ttaagatttc cagaatatgc
    27601 tgctgaggta ttaagtacag ttgttgaaca aataaaagac ttagatatag acttagtagt
    27661 aggaccagct atgggtggag taatagtttc ttatgagtta ggaagacaat taggaaaaga
    27721 agctgtattt actgagagaa aagacaatac aatggagtta agaagaggat ttgaagttaa
    27781 aaaaggagca aagataataa ttgctgaaga cgttgtaact actggtaaat caactatgga
    27841 gacaaaaaga gtattagaag ccttaggtgg agaagttgta ggtgttgcat gtatagcaga
    27901 tagaactaat catgatatag gtatgcctat atatagtgct ataaaacttg atattcaagt
    27961 ttatgaatct gatgagtgtc ctttatgtaa ggaaggaaaa ttaccagttg ttaagcctgg
    28021 aagtagagag ttcaaggaat tagggatgta ataaaaactt aattatttat agtgttactt
    28081 aaaaaatgta aattttttag agtaaaaatt tgtaatataa catataactt aaaaataaaa
    28141 agcagttagc cttataaatg aaggttagct gttttttttg ttaaaaatat atttacaaaa
    28201 taagagatag tagcagtaca atataagtat aaggtaaaag tattatatat tagggagggg
    28261 taagtatgaa aaatcaatta aatgaaaatc ataaaaaggt tgtatttttt ggagtaggtg
    28321 ctgtaggagc tacttttgca gaacaatttt ttaactctaa atatgatttt aaaattcttt
    28381 gtgataatga aagaaagaaa agatatttag aagaaggatt tataataaat ggaaaaaggt
    28441 atgattttaa ttatgtaact aaagatgagt ataaacaaga ggctgatttt ataattatag
    28501 gtctaaaata taataattta aaagaaaata taaaagaatt agatggatta gttggaaaaa
    28561 atacagttat aatgtctctg ctaaatggag ttgatagcga agagataata ggagaaagat
    28621 ttggaattgg aaaaatggta tattcatatg ttaccaatat agatgcaaag aaaatcaata
    28681 ataatattat acacactact aatgggataa ttgtatttgg taacaaagat aatagtgaag
    28741 atagaaaaac taatataata actgaagtct ttgatgatgt aaatatagaa tatattttat
    28801 caaaagatat tcaacgagat atgtggtgga agtacatggt taatattggt gtaaatcaaa
    28861 cttcagctat acttggtgca ccttatggag tttttcagag ttctgagcat ttaagagaat
    28921 tagcaaaatc tgcaatgagg gaagttgttg ctatagcaca agcaaaagac atatctctta
    28981 cagaagatga tgttgaaaat tcattacata gaatactaga acattcaaaa gaaggaagaa
    29041 catcaatgct tcaagacgtg gaagctcata gacctacaga agtagatatg ttttctaaga
    29101 atatctgcaa acttggaaaa aaatatagca tacctactcc tataaatcag actttatttt
    29161 atatgataaa agtaattgaa agtagatttt aaagggtatt tgtaagaaat attgataatt
    29221 attgatttta aattttatta atgttatata ctatttaagt tactaaatat ttttaactct
    29281 tcaatgaaaa tagttgctgc ttttgacaaa gttatatctt ttggaaatat atatgagaaa
    29341 tgtctgttgt agctgcttcc aagctctatg acagacagct cattgtttaa aacaggtaag
    29401 cttgtcacta gattagaaac tattgtaatt cctaaattat ttctaacaga ttctttgaca
    29461 gcataattac ttccaaaaac catcatactt tttggaataa tttctttaac acttaaaaac
    29521 atatctaaat agtctctggt tccagaacca tcctccctga ctatccattt ttggtcttga
    29581 agtttatcaa aactaaaatc ttttaataaa tgactattgt atggaagtgc taaaaccatc
    29641 ttatcttcaa aaaaatattc ttgaataaat gaaggggaag agcaagtgcc ttcaataaga
    29701 ccaatgtcta aaatataatc cttaacatga gaagatacga ttgatgtatt ttttataaaa
    29761 acttctacat atatgtcagg atacttttga gaaaataatg ctaaaaaatt tggtagaata
    29821 tattctccaa tagttaaact tgcaccaatc tttaagtgac cagttatagc atctgaaact
    29881 tggcttacat catgataagt aatatttaaa agatttaata tttctttagc tcttttgtac
    29941 aatatttgtc cactttctgt tataaaaatg gttttttgtt taatagacct gtttataagc
    30001 acaactttaa aataattctc tagatttttt atgtgtttac ttacacttgg ttgtgataga
    30061 tttaagtatt ccccagcttt agtaaagttt ttgtattcaa caacagctac aaatgttttt
    30121 aattcttcaa acaatttttt gtctccttca cctaatgaaa ttttacattt tttatatact
    30181 ttctacagat aattatacta tatataataa ccattaaaaa cattaatcat tacgatatta
    30241 tatatttatt ttacttatgg ttattacaat tatatactat tgctatgaag aaaactatat
    30301 taattataag gtaggtatat tatgttaaag aaaaaaagca gtttgacatt aaaaactata
    30361 agggaaatat taccaggact gtttatatca gtgttagtag gttatattag tatatttatt
    30421 tctattttaa ttcctaaggt aggggcagca tcaatttcta tatttttagg tatgtttgta
    30481 ggaaacctat ttttaaatca aaaggtattt caaaaaggtt ataaattttc agagacagat
    30541 ttgttatcat attcaatagt actattaggg gcaacactca gtgtatctac cttaatagac
    30601 ttaaaagttt caggaatttt atttataata ttgcaaatga caataacaat aatagctgca
    30661 ctttatatag gtaaaaaact aggatttgaa gaaaacttta gatttctaat ggcaagtgga
    30721 aatgcagtat gtggttcttc tgccatagga gcaatagttc cagtggttaa tgcgacagat
    30781 aaagaaaagg gaattgcagt aactattgta aatgttactg gtatattcct tatgttttta
    30841 cttccaataa tatctcaatt tttatatagc catgaacttg taaaaacttc agcaatgata
    30901 ggtggaactt tgcaatcaat tggtcaggtt gtagcaagtg gagcaattgt tggagaaaat
    30961 gtaaaagatt tggctactat ttttaagata gtaagagtaa tatttctagt tgttgttgta
    31021 ttagtatttg gacatatgaa aaatcagtct aatagggaaa tccttgaaga agaaaaggat
    31081 gagataaaaa agaaaaaagt aactatacca tggtatgtaa ttggattctt tataacttgt
    31141 gcactttttt caatgaacat tataccaaaa gaagtatctg tgttgtgcaa agaaataagt
    31201 aacaaactag aaataatagc tttagcagca attggattaa aagttaatgt aaaagattta
    31261 gtgaaacaag ggaaagaagt ttctttatat ggtttatttg taggtacagt acaagttgta
    31321 tcagctgtag ttttaataaa aatatttata tagcacaaaa atagtatttg taatattaat
    31381 ttgattaatt aaaataatat gatactaata atttataata taaataaaaa atgaatttcg
    31441 ataagtttaa gtgggtataa acttatagaa attcattttt tatttaaggt aaaaatttaa
    31501 agtaaaatat tattttacat aataataacc ttataaattt tgaaattact tatctttgtg
    31561 ttaaaataag taaaatacac atattaaagt taagttttta ggcaaataaa caaaatgaaa
    31621 atataaatat taaggagatt tggtatatga atgtttatga aaaaggtaat ggagttatac
    31681 tagaaggagt aacagatttt gacccagtac atatatttga gtgtggtcaa tgttttagat
    31741 ggcacaaaca agaagatggc tcatacactg gagttgcaag ggggagaata ttaaatgtca
    31801 aaaaagagaa tgataaaata tatttaaata atacgaattt aaaggagttt aacagcattt
    31861 ggtataatta ctttgattta ggaactgatt atacagaaat aaagaataag ctaaaaaata
    31921 tggatgaata tttgaataag gctactgaat ttggatgggg aataagaata ttaagacaag
    31981 atggatggga aatgcttata tcatttataa tttcctctaa taatagaatt cctatgatac
    32041 aaagagcgat agaaaattta tcaagaaagt ttggtaagta tataggtgaa tatgaaggta
    32101 atgaatacta tgcattccca acaccagaag aactaaataa ggcctcacaa gaggaaataa
    32161 gagcatgtca aacaggtttt agagataagt acataaaaag tactacacag gcagttatag
    32221 agaataatga tgaggtatct gaatatacaa atttaagtac agaggattgt agaaaagagc
    32281 ttttaaaatt taatggagta ggaccaaaag tatgtgattg tattgcatta tttggtatgc
    32341 aaaaatatga ttcttttcca gttgatgttt gggttaagag agttatgcaa gaattttata
    32401 tagatgaaga catgagttta cctaaaatga gaacttatgg aatcgataaa tttaaagaaa
    32461 tgtctggatt tgctcaacag tacttatttt actatgcaag agaactcggt ataggaaaat
    32521 aaattaaggg ggagaaatta tgggagtaat aggaacaata tttctgttct atttaattat
    32581 atcatatcta gctggagcca taatttctgt gattatattg cttgaaaata gagaccctgc
    32641 aaaaacaatg tcttggctat tgatgtttat tatatttcca ggtgtaggtt taatgatata
    32701 tgctatttca ggtagaaata ttagaaaaag aaaattattt aagactcaaa aactagctaa
    32761 taatataaaa gaaaagaaac tatttgatac attagaaaag ataacagaaa tagttgaatt
    32821 agaaaaagaa tctataaaac aaaataagct tttaagagat gaagaggatg gtagttatag
    32881 aaaaagggta ataaatatgt tgttaaagac tggtatgttt ccctttacta aaaataataa
    32941 agtggatgta tttgtagatg gaaatgaaaa gtttaaaaga cttatagaag atataagaga
    33001 agctaaagac catattcatt tagagtactt tatcatcaaa gatagtgaaa taggtagggt
    33061 gttaaaagaa gaacttataa aaaaggctaa agaaggcatt aagataagaa ttttatatga
    33121 tgatgtagga tgctggagat tttggtttaa tagaaaattt ttccgagaaa tgagggaagt
    33181 aggtatagaa attgcagcat ttttacctac aaaatttcct ataataggag ggaaattaaa
    33241 ctatagaaat cacagaaaaa ttgttgttat tgatggaata attggatata caggtggaat
    33301 aaatatagga gatgaatatt taggcaaaaa tgataagttt ggatattgga gagatactca
    33361 tattaggatt aagggtattt ctgtatacat gcttcaaatg acatttctga ttgattggta
    33421 ttatacgaca aaagaagtat tagtgactaa aaattatttc ccaagtgtag ggaatgttgg
    33481 tgaaagtatg atacaagttg ttgcgagtgg tccagacagt gactgggaag atattcatta
    33541 tgcttatttt tctgcaatat gtcaggctag aaaaaatgtt tatatagaaa ctccatattt
    33601 tattccagat gaaagtctac taaaagctat aaagagtgct gctcttagtg gagttgatgt
    33661 gagaataata tttcctaaaa ttgcagacca caagatagta aatatagcat cttattcata
    33721 ttttgaagaa atattaagag caggtggtaa agtttattta tataataaag gatttataca
    33781 ttctaaagtc gtaataatag atgataaaat tgcttctgca ggtacagcta atatggattt
    33841 aagaagtttt atgcttaact ttgaggtaaa tgcatttatc tatgatgaag aagttattag
    33901 ggtaatgaca gatgatttct ttgaggattt aagtcactgt gaagaactta atttggaggt
    33961 atttaagaat agaaatatca tacaaaaaat caaagaatct gtagcaagat tattttcacc
    34021 aatattataa aaaattatta aaaaaggtat tgaaaattat gtgtgattgg tatattataa
    34081 taattgttag cactctatta gatagagtga taataaataa aaagtatata tataaatcta
    34141 catatataag tagtattaat ttaaaaataa ctaaaaacat aggcgaacta gtctatactt
    34201 aatattttag gaggcgtgaa taatgaaaat aagaccatta gctgacagag tagtaattaa
    34261 aaaagtagaa gcagaagaaa aaactgcaag tggaatagtt ttaccaggag cagctaaaga
    34321 gcaacctcaa atagctgaag ttgtagaagt tggaccaggt ggaatagttg aagggaaaga
    34381 aataaaaatg gaattgacag tgggagataa ggttatattc caaaaatatt ctggaacaga
    34441 agttaagata gaaggacaag aatacacaat actaagacag agtgatgtat tagctgttat
    34501 tgaataaata tagaataaat ttattaggag ggatttaaaa tggctaaaga aattaaattt
    34561 tcagaggaaa caagaagagc tttagaagct ggtgtaaata aattagcaga tacagtaaaa
    34621 gtaacattag gacctaaagg aagaaatgtt atattagata aaaaatttgg ttctccactt
    34681 ataactaatg atggagtaac tatagcaaaa gagatagaac tagaagatag atttgaaaat
    34741 atgggtgctc aattagttaa agaagtagca actaaaacta atgatgtagc tggagatggt
    34801 actacaactg ctacagtttt agcacaagct ataataagag aaggtttaaa gaatgtaaca
    34861 gcaggggcta acccaatact tttaagaaaa ggaatacaaa aagcagtaat agtagcggta
    34921 gaagaattaa aaaatcaatc aagaatagta gaaacacaag aggctatatc tcaagttgct
    34981 tctatatctg ctggtgatga agaagttgga aaattaatag cagaagctat ggaaatagta
    35041 ggtaaagatg gagttataac tgttgaagag tctcaaacta tgaatactga attagatgct
    35101 gttgaaggta tgcagtttga tagaggattt gtttctgcat atatggttac agatgtagat
    35161 aaaatggaag cagttttaaa tgacccatat atattaatta ctgataagaa aatatctaac
    35221 atacaagaat tattaccagt tcttgaacaa atagttcaac aaggtaaaaa gttattgata
    35281 atagctgaag atgtagaagg tgaagcatta tctacattag tagtaaataa attaagagga
    35341 acatttgatg tagtagcagt taaagctcca ggctttggag atagaagaaa agaaatgctt
    35401 caagatatag caatacttac aggtgctcaa gtaatatcag aagaattagg ttatgattta
    35461 aaagaagctg atttatctat gctaggtaga gcttcatctg ttaaggtaac taaagaaagt
    35521 actacaatag tagatggttc tggagataaa aaagctatag aagatagagt aactcaaatt
    35581 aaacatcaag tagagcaaac tacttcagat tttgatagag agaaattaat ggaaagatta
    35641 gctaaacttg ctggaggagt agctgttgta aaagttggag ctgctacaga agtagagtta
    35701 aaagaaagaa aattaagaat agaagatgct cttaatgcaa ctagagcagc tgtagaagaa
    35761 ggaatagtag ctggtggagg aactgctttt gttagtgtta taccagcaat aggaacacta
    35821 attgagagtt tagaaggaga agttaaacta ggtgctcaaa tagttaaaaa agcgttagaa
    35881 gagccattaa gacaaatagc tataaatgct ggtcttgaag gtgctgtaat tgtgcaaaat
    35941 gttgttaatt ctgaagcaga aactggattt gacgcattga atgaaaaata tgtaaatatg
    36001 atagaagctg gtatagttga cccaactaaa gttagtagaa gtgctttaca aaatgctgca
    36061 tcaatagcaa gtactttctt aactactgaa gctgctgttg ctgaccttcc tgaaaaagaa
    36121 gatgcaggaa tgccaggaat gggtggcgga atgcctggta tgatgtaatt taaaaaattt
    36181 aaaatataaa ttttaatata aagaactatt tcgacttaga ttttaaactc taagttgaaa
    36241 tagttctttt gtatatatct aatttttgta tatctataaa ttcaatacac atatttagat
    36301 aatcagtatc tagtttgtaa taatatttta gagtagtatt gttatttttt aggttatgat
    36361 tttagatata tattaattaa ggtataattg ttgatagaga ataaatcaaa tttaaaagga
    36421 tgcgataata tggacttaag aaaattactt gaagaagtta aaaatgaaaa tattgatata
    36481 gattttgcgt tagaaaagtt aaaagattta ccttatgaag accttggata tgcaaatata
    36541 gaccatcata gagaattaag aaatgggtat ccggaagtta tttattgtga aggtaagagt
    36601 gatgagcata ttttagggat tattgataaa atgaatcaaa aaagttctaa catattgggg
    36661 acaaggtgca gaaaagaaac ttttctgaaa attaaagaaa tctataatca tgctgagtac
    36721 gaagaggcgt ctaaaattct taagattcaa aatcatgata tagagaatat aggaaaaggt
    36781 aaaattgtga ttgctacagg gggaacttct gatataccag tagcagacga agcttatcat
    36841 acagctaagt ttttaggtaa tgatgttgat agaatatatg atgttggagt ggcaggtata
    36901 cataggcttt taaataaaag acataaaata gatagtgcta gagtaatagt agccgttgca
    36961 ggtatggaag gtgctcttgc aagtgtaatt ggtggactgg ttgatgttcc agtaatagct
    37021 gttccaactt ctgttggata tggagcaaat tttggaggat tagcagcatt actagctatg
    37081 ttaaatagct gtgcatctgg aatatctgtt gtaaatattg ataatggatt tggagcagga
    37141 tatttagcat caatgataaa taaactgtaa atacattgat ataaattaaa caaaactata
    37201 taataaaatt taatttctat tatattttta ctattaaaat tgaggagaca tatatgagtg
    37261 aaaaaatact ttattttgat ataataagcg gtatatcagg ggatatgacc cttgcaagtt
    37321 tattaaattt aggtgtgcct aaggaaattt ttttggagga aattcataaa ctaagaatga
    37381 gcgatgaatt taatataaac atcagctcga aaactgaaaa tggaatagta ggtacaaaag
    37441 tagaagtaat tacaaaagaa aaacatacac atagaaattt agtggatata tttgaggtta
    37501 tagataaaag cactctaaac gaaaatgtaa aatctaaagc aaaaaaaata tttatggtaa
    37561 ttggagaagc agaagcaaaa gttcatggaa ctacaataga caagatacat tttcatgagg
    37621 taggggctat agattcaatt gtagatatag taggagcttc tatattagtt gacttacttt
    37681 gtgtagataa agtttgtgct agtacagtgt ctgttggttc aggatttgta aaatgtgaac
    37741 atggaattat acctatacct gcacctgcaa ctatagaaat tttaaaaggt gtgccaatta
    37801 aattaaataa tgtaaatgga gaatgtacaa ctccaacagg agctgcaatc ataaaagtct
    37861 tgtgtgatga gtttgtagat gagcttgaat tttctccaaa gcaaattgga tatggtatag
    37921 gtcataagaa gtttgaagta ccaaatatac tcagaactgt attaggtgaa aaaaaaaaga
    37981 agaattaatt tatgaaatta gtgcaaacat tgatgatatg tcttcagaaa tctattctta
    38041 tttgtatgaa aaaatattag atgagaaagc attggatatt tatacagaga gtatttatat
    38101 gaagaagaat agaccagcaa caaaagtatc aattttatgt aatgaatcag atttagaaaa
    38161 gtttattaaa atattacttt tagaaactag tacttttgga gtgagatata atgcatataa
    38221 tagagaaatt ttagagagaa aatttgtaaa attagataca aaatatggag tggttacagt
    38281 aaaactaggg tattataaag gaaaactagt caaggttact ccagaatata atgaatgtaa
    38341 aactatagca aaaaatgaag atattcctat aaaaaaagtg tttgctgata taaattttag
    38401 aataaaagaa gaatttagtg aaaacttatt gacataagta ataaattttg ataaattaat
    38461 attcagcctt attaaataaa agtaaacaga aaaaaatata taaaatataa actcactcgt
    38521 atatgctcag aaatatggtc tgagagtctc taccaagata ccgtaaatat cttgactatg
    38581 agtgaaatta ttataccaaa agacctagtt aagtaaatgt gtaggctgag ttatactccc
    38641 tatgtgttgg ctataagata aaggtatttt ggaagcctgt atagtaattt cacttttgct
    38701 agaaattatg gaagttacta tacaggtttt ttgtgtaaaa agatttaata taatttagac
    38761 tgtattgtgt taaaataaat atataaaaac tatattatac aaggagagat gtgaatttat
    38821 gaaacatgaa ttagtacttg taatagattt tggaggacaa tataatcagt tgatagctag
    38881 aagagttaga gaaaacaacg tatattgtga aatacttcca tgtactgcaa gcatagaaag
    38941 aataaaagaa aaaaatccta aagggataat atttacaggc ggtccaaata gtgcgtattt
    39001 agaagattct ccaacaatat caaaagaaat atttgaacta ggagtaccaa tacttggaat
    39061 atgctatggt attcaaataa tgtctcatgt attgggtgga gttgtaagaa aaggtaataa
    39121 acaagaaaag gaatatggaa aaacatctat aacttatgga aaatcatcat tatttgaagg
    39181 aataactaca aatagtgtat ggatgagtca tacagattta atagaaaaag ttccagaagg
    39241 atttactata gttgcaaata ctaatgattg tccagtagca gctatggaaa atgtagaacg
    39301 aaacctatat ggagttcaat tccatccaga ggtagaacac tgtttggaag gggacaagat
    39361 acttacaaac ttcttatata atatttgtaa agtaaaaggt gactggacta cagattcatt
    39421 catagaagat aaaataaaag aattaaaaga aaaaataggc gataaaaaag ctttatgtgc
    39481 tttaagtgga ggagttgatt cttctgttgc tgcagttctt attcataaag caattgggga
    39541 caacttaact tgtatatttg ttgaccatgg tttacttaga aaaaatgaag gaaatgatgt
    39601 agaaagaata tttagagaga aatttgatat aaatttaata agagttaatg cagaagatag
    39661 attcttatct aaattaaaag gagtttccga accagaagct aagagaaaaa taataggtga
    39721 agaatttata agagtatttg aagaagaatc aaataaatta ggaaaaatgg atttcttagt
    39781 acaaggaaca atctatccag atgttataga aagtggacat ggaaatgctg ctactataaa
    39841 gtctcatcat aatgttggtg gaatcccaga agatgtagac ttccaagaaa ttgtagaacc
    39901 attaagagag ttatttaagg atgaagttag aaaaatagga ttagagcttg gtatagaaga
    39961 aggattaata tttagacatc ctttcccagg accaggtcta ggaataagag ttataggtga
    40021 tgtaactaaa gaaaaatgtg atatattaag agaagctgat gctgtttata tggacgagct
    40081 tagaaaagca ggtttataca gagaaatatg gcaagctttt gcaacattac cagatgttaa
    40141 gactgttgga gtcatgggtg atgaaagaac atatgcttat ttagttggtt taagagcagt
    40201 tacttcttct gatggaatga cttctgactg gtataagatg ccttatgatg tattagaaag
    40261 aatttctaat agaataataa atgaagttga tggagtaaat agagtagttt atgatataac
    40321 ttctaaacct cctggaacta ttgaatggga ataaaatata gaatgccaga aatccacatg
    40381 aatacaggat ttgaggtctc tcttacttct atattatact ggtttgatac tatcaatatt
    40441 tgccagtatc ttatggatta ataagcaaaa aacatcctgc tgaatggtaa attcggcggg
    40501 gtgtttttat tttgttttga aactcctttg ctctgaaact cgaagtattt aacactgatg
    40561 atgttgttat cttttagttc cttttgtgtc atgctctgaa agacaaattg atacaataaa
    40621 aaagtaattt cttaatcatt gatggagata tgtatttatg ttactcttga tggtaatttg
    40681 agtaatattg ttcatagctt tttatattca cttaattaga aaaccatttg gtataatcat
    40741 aaataaactt gatgatataa tagaaaagat ttataattat tagaagtata taaaagtatt
    40801 ttatgtctat gaaatgtatg tctataaaac atatagatga cttttgtata ttaatgtatg
    40861 aatattgata ttatagaaga attgagttgt caatgatact aaatcaaata tttatagaag
    40921 atggagggat tatgagaaat aaaataatta taggaattac tttttcactt gtattactaa
    40981 tgtctggatg tgcttcaaaa caaacagcag aaataaacgt attagcaact actgatttac
    41041 atggagttat accttatgag ttaacttctt atgtaaaaga agaaagaaaa aaagataaaa
    41101 atctaacttt agtagatgca ggagattttt ttgatagtgg agaagtgttt ggttctagca
    41161 tggatagtta ttttagtgct agatataaag atggtgataa taacactgaa agttatattg
    41221 agacgcctat ttcaaaagat atgaaagagg taggttatga tgttgcagtt cttgggaatc
    41281 atgaatttat atccaacaat aaattttatc tagataatat gatatctgat tttgagaaac
    41341 aaaaaataaa tattttatcg gcaaatacgt ataaaaaaaa tggagatagt tatacaaaac
    41401 catacataat aaaaaatatt aatacacctg aaggaaacgt aaaactagga attttagggc
    41461 ttactataaa agaagttggt gagaggaaac agtggaaaga tggaaaactt gttgactcta
    41521 agtctttaga actaaaagac caagagggct acaatggtga attgtatatg aatgatttag
    41581 tagaagatgc taaaaagtgg gttggtataa tggaaaaaga gaagcctgac attatagttg
    41641 ctgtggcaca tacaggtgag aaacctaaga aacctagaaa cccaggaaat agaatacaag
    41701 acttagctca acaagttgat ggaattgatg ctatagttgc aggtcataat catgttcaaa
    41761 ttgagcaaca tgattataaa aataaatcag gagaaaatgt tatagttact gagccaggaa
    41821 agcatgggga atatatttct aagattaatt ttaaattaga aaaaaacaat gataaatgga
    41881 atatagttga caaatctagt aaattaatta aatttgaaaa aaatcaagaa agtgataaat
    41941 ttggagaatt tatttcttca attaataaag taagtaaaga taagaaagaa ataagattat
    42001 cagaagtaaa gactcctgaa tgggataaaa tatatgtttt taaatctgga acatctgcag
    42061 atgatatata taaaacaata ggatataaat ggagaaatat atcatctcca aagggtgatg
    42121 acatggtgca gattgttgta atgaataata ataagcctgt tagctatata tatggtgaag
    42181 ctgaagttat gccaattaat ataaaatgtg atgaatcaga gtataaaaat aatgttgtaa
    42241 ctatttatcc taataaaaat gataaattta aaattgaaaa aggtaagcaa gaatatagta
    42301 ttaatttaaa acatatacaa tagaaacttt tatcttattt aagtttagat tgtacttaaa
    42361 ataaagtgtg tattatttta aaaagtgatg ataattaaaa tcacaacatt aaggaatagt
    42421 acacactttt tatgctaaaa aatagaatgt taaaaaatta aacctttaaa ttaaagtaca
    42481 ttgcttatat tatccaatat tatttccaaa ggttgtgtaa tatttttatc cttatgtaat
    42541 attgctaaca ttttattttc catatctatc tcatctaatt caatcaatcg caatttttta
    42601 tgtaagagtg aatctaataa taaattttct ggcaaaatgg ttatacctaa ccctgcttct
    42661 gcagctttaa taagtgcaaa agaattaaca ctttcccaaa caggataagc tttttggttt
    42721 gaaagagata atacactgtc caaagtatcg cgaatagcac ttccttgttc acgtaacaat
    42781 aacggaaacg tgcataactg tcgtagagat aaggtttgtt cagataaagg aaaagttgga
    42841 gcacatgcaa cacataactt ataggaacct aataaaattg tacggaatgc cccctgtggt
    42901 tctatacctt cccaaaaaca tatatcagct tctccacttt ttaaaatatc catagctgaa
    42961 ttagcacttt cgacacgtac attcacttta agagatggaa atgaattttt tagtcgactt
    43021 aaaattggtg gaagtaaaaa agaggcaatt gtaatgctag aaacaatgtt tataggtgta
    43081 cattcttcta aacgactgat ttttttgtct aaattgcgac aagcagttaa gatactacgt
    43141 gcttcatcta aaagagaaat gccacagcga gtaagacata cccctcgtgg taatctgtca
    43201 aatagtgatg tttcagcttg ttgttcaagt tcagctatag catgagatac agcagattgt
    43261 gtgatatgta atttttttgc agcacctgta aaagtgcctg tttgttcaat tgcttctaaa
    43321 atctctaaat atcgtatgtt tatcataata aatatcctca ctatacatga ataaaattaa
    43381 ttaattccat taaattctat cattttacag attgcaaagc aacaggtata ctgaataata
    43441 tgaagtgaaa agaaggagga atattttgaa tcaaagcaga aaaatatatt tttggctttt
    43501 aattattaac ttgtttatta gcacattcac ttttggcgga gggtatgtag ttgtacctat
    43561 gattagacgt tattttgtaa atcaaaagca attctttaca gaagatgatt tgatgagtat
    43621 ggcagcagtt gcacaatcaa ctcctggagc tattgcaatt aatttatctg ctttggcagg
    43681 ttatcgagta gctggtactt taggggttgt cattagttgt acagcagcta taatacctcc
    43741 actcgttatt cttggattag tatcagcatt ttacaccact tttatatcta atgccattgt
    43801 aactgcagta ttaaaaggaa tgcaagctgg tgttgctgca ctaattgtgg atttgattat
    43861 tgacatgtgc tctatgatat taaaacaacg ttctttgttt ttatcaacta tgatacctat
    43921 tgctttcttt gcaaactttg tgatgagtat aaatgtaatt tttatattat ctgtttgctg
    43981 ttttgtatgt gtaatgcaag ttttctataa gaagagggaa aataaatgaa tacaatttgg
    44041 aacttatttt ttatattttt aaaaataggc ttgtttagta ttggtggtgg ttatgcaatc
    44101 atacctttaa tccaagagaa agtagtaaat caaactggat ggataagtga gaaaatgttt
    44161 acagatatta taactatttc acaaatgaca ccagggccac tggctgttaa tacttctact
    44221 tttgttggac ttcaaattgg agggttttgg ggagcagttg cagccacttt aggttgtgta
    44281 ttatgtggtg tagtaatatc tctattttta tataattttt ttcaaaagca tcagaactct
    44341 acttatatat ttgaaatatt aaatggtcta aaatcagctt cattaggttt aattatctca
    44401 gctgcggcta caattataat ccttgcatta tttgggacga ataaagtgta cttcaattct
    44461 atatttgaga tgctaaactg gactgcacta ataatctttt ttgttatact actgatagta
    44521 cgtaagtgga aaattaatcc tattgtgatt ataataataa gtggtatact aggaatattt
    44581 ttttatttat aagtttttgg taagtaaagg atatctattt ttttatatct taaatccaaa
    44641 tagccaataa agtaaggcta tttggatttt taataaattc tgaaaagata atcagaaacc
    44701 catataacat ttaaattata tcactggttt tctacaaacc aatcataagc ttcttggcaa
    44761 aatttctcac tatctatata gtaactatta tgaacattat taatttcaac aagtttcttt
    44821 ttacatttta gtgaattata atagctatca aaatattggg ttttaaaata tctatcatga
    44881 agtgttttaa agacaagagt aggtatgttg actccatctt ttatcttact atcttctgca
    44941 ataaagcatt ctaacattgt attaattatc tttgtactat ttttccaaat atgaggattt
    45001 ttcttttcaa atattttata aaattcatta tcatagactt cattataacc tttatattta
    45061 ggtggtttta ctgttatgtg aaaattagga agaaacttaa agaaaaaata taataatttt
    45121 tatgttctgt tttatatatt attcatattt tatcacagat aatatactaa agttaatttt
    45181 tttattgtac aactattata ataattcttc tataatataa gacattctat aattttatat
    45241 ttaagttcat gtgtatttaa ttgtttttat ataaaatgtc cagtaatact atttggattt
    45301 atttttattt catcaggagt tccagaagca acaatttccc ctccatttat tccactgtct
    45361 ggacctatat cgataatcca atcagaagca cgtataacct ctgtattgtg ttcaataatt
    45421 aaaagtgaat gctgttcatt tacaagtttt ctaaaagtaa tcaacaaatt ttctatatct
    45481 ttaaaatgaa gtccagtagt aggctcatcc aatatgtaca gcattcgttt tttagttttt
    45541 gtccctaatt cttttgctaa ttttatcctt tgagactctc ctccgcttaa tcctaatgta
    45601 ttttgtccaa gctttagata tccaagtccc acttcatcta ataaggagag ttttctatat
    45661 atatcagagc aatcactaaa aaatgttttt gcttctgcta cttccatgtc aagtatatct
    45721 gcaattgttt ttcccttgta ttgtatagac agtatttctt tttgatatct cttaccttga
    45781 cattcattac aagttaccca ttggtctgcc atatattgta gaataatttt tgttttacct
    45841 aatccttgac agtttgggca ttgccccttt ttgctattaa agctaaaata gctttcatcc
    45901 aataattttt gttttgcttg tggagtttca gtaaatagag aacgaatttc atcaaaaata
    45961 ttgatatatg tagcaggtgt agaacggcta gattttccaa taggtgtttg gtccattaag
    46021 ataaaatcgt caatagcatc aaatccagta agtgcagtat aatttttatt tgggatagat
    46081 ttttgtttca atttttcttc tagagcagga agtaaactgt gaaatacaag agaactctta
    46141 ccagaaccac taacacctgt aatagagcac atacagttta agggaatttc tacatcaata
    46201 ttttttaagt tatttgcatg gcatcccttt aagcttaacc atttacttgg tataatttta
    46261 ttttgtgaac ttatcttatt gtatgtactc aaatatttgc ctgttataga atttggattt
    46321 tttataattt cttgggttgt accttctgca atgatgaagc ccccttttgt accagcattt
    46381 ggtcctacat caataatata atcagcagac agtattgtat ccttatcatg ttccactact
    46441 ataacagtat tacccttgtc tcttaattct tctatcattt tgatgattag attatggtct
    46501 cttggatgta aaccaataga tggttcgtct aaaatatagg ttaatcctac taattcactt
    46561 cctagctgac ttgataatcg tactctctgc agttctcctc cagataaagt tggagctgtt
    46621 ctatctgttg atatatagct aagacctacc tttaatagat aactaactcg aatttttaat
    46681 tctgttaaga tatcatttac caaagatagc tcattttttt gaagttgatt tggtaattca
    46741 cacaaccaat tccataactg ttctatcgtc atttttgtta gttcagggaa gcgataacct
    46801 ttgattgtag tgaatctagc ctcaatgcac agcaattcgc caccacatgt attgcaagga
    46861 attttgttca tatattgatg caaggtatta ttttcagaac tagattctct aaaaagtctt
    46921 tgaatgtggt tgattgctcc tgaagcaggc cttctaatct ttgattctcg tccctttgat
    46981 tcaaagctaa attcatatat cttatcgtct gtaccatata agattgcatc tataaaatct
    47041 cttggcaatt cattccaagg tatatctagg tctatatttt tatcttttgc tattgcatat
    47101 aattcaccta ccatccaatt accatttggc tttttccccc tcaattttcc aaaatagtaa
    47161 gtagctccat ctaatattga aatagttggg tcttttacaa ttaattgagg attaacttga
    47221 taggtaaaac ccaatccatt acaatcgtga caagctccag tatgggagtt agcattgaag
    47281 gttgaagtat ttatcttaga aaaaatagtt tggcaatgtg gacaataatt ttttgtatta
    47341 ttcttttttt ctaatggagt tttgcaatat ggacagtaac tttttccgat tgatacaaat
    47401 aacattctta agtaatccca aatgcttgta agagtaccaa cagtagaacg aggattttgg
    47461 cttccttttt tctgttcgat agctatagta ggggttaatc cctgaagtaa atcaaattcc
    47521 ggtttttgaa gctgttctga aagttttgct ccattaccta gattttcaaa ataacgtctt
    47581 tttccttctt cataaatcgt atcgaaagct aaagaagatt ttccactacc acttacacct
    47641 gtaataacag ttatttgatt ttttggaatt gtaacctcaa catcctttaa attgttttgc
    47701 cttcctcctt ttagatagat agagctttta ttatgacaaa gtgaattttt aattgattta
    47761 tttattgctt ttgcaaattt gaatttcttt tctagttcaa gaggattgcc taattctttt
    47821 atttccgaaa tacctaatat ttttaactga gaaaagattg atttcaaata atcttcaggc
    47881 aatttttcta ttaacaaatt aaggtcttct atttttatat ttccgcttga taatatctct
    47941 gccatttcat ctaataaatt tttttctgct cttgttaatt gattgtattt tttggaactt
    48001 aattctgtcc ataaatccca tggaagcaat tctaaaccaa tcatattatt aaagtcatgt
    48061 agaagattac cctttacaga atgccaacct ttccaatttt tattatatcc aaagtcatct
    48121 ggatgagcat gtccttgtcg acatcttatc caggcttctg aaccagttaa aaaaccatct
    48181 gtttttccga catcatgagt gtcaaaatta atttgaaaat aatttttttg tatgtcatct
    48241 atttgtgcat ctattcttat ccatctcttt gttagagtat catagtattc tacaagccag
    48301 tggtcttcat aagtaagctc attttcaaaa taattagcaa aacctgctct cattctagcc
    48361 tcaaaacctc gatatcttag gagcgataca agaagtaaag aataatctct gcacattcca
    48421 acaagccttt gttttgggtt tcttggaata gttagtgggt tagaatttat ttcaaatatt
    48481 ctttttaaca tttgaggaat tgtacgaagc aattcctcat cagattgttg cttattaaag
    48541 gatataccat ataattttcc ttggtctcca tgaattacta ggctttgaac cacttttaat
    48601 aactcaattg gagtctttgg taaatcttga tatttatttt caaatttttt aggatttgtg
    48661 atgatgcttt gatttttata gttatttatt ttcatttata tttcacctct ctaaatggat
    48721 gatataccct gacatggtgt catatgcaag gacaatttag attttttggc caaaatttaa
    48781 aaataaataa aaaatgatac agtgataaat tgtaatacaa atatagtttc aaattgcata
    48841 taatataatt atttaataaa accattatct atggaatgtt aatgaaatgt taagatggca
    48901 ttcttgaata ttaagaaata gaatactata atatagtgtg aaggattctt agtaaaaaaa
    48961 tttgtaagtg ttaatataca ttaaaaaata ggtttataat ttggaggaaa aaaatgaaat
    49021 tatcaaggta taagaaaaat agtttagttc tgtctataat tttatgttca cttattattt
    49081 caatccttgt aattactgtt tttaataccg taaaactaca caatatatct aataaacaat
    49141 ctaaaaacta tttaaacgat gtatctacac agattgtaat gaatgttgat tctaaaatca
    49201 aatttatttt atccgactta agaataatgg cagattttat taagcaatat gaaggtgata
    49261 gtcgatatga gtatttatct aaaagaaaga ctagttataa gtattatgat gttggaataa
    49321 tagatttaga aggtaaagct gagtttttaa gtggaaaaaa gtttgactta aagaatactg
    49381 cttcctataa aaaaggaatt gaaggtaaag aatactcaga agtaatagag tcaatgggtt
    49441 ttgttcttta tagtgtacct atatttaacg ataatcatga agtgtctagt attttaatag
    49501 gtgtatccaa taaagaaagc atggatgaga ttcttaatat agatagcttt aatggagaag
    49561 gaactattga aattattaat agtcagggaa aaactctttt cataggaaaa aataatgagt
    49621 taataaaaga ccttagctat aagtataagg attctgcaga tgaaccttgg gcacaaaaga
    49681 tgcttaatga ttttaaaaat gataaatcag gaaatattac aataacctca tcaaaaggtg
    49741 tacaatgctt attaacttat catccaatta caagaggttt aaatgattgg cattttcttc
    49801 tcatagtacc tgaagatgtt gtacttggtg aacttaataa gttaaattct tttacaataa
    49861 taatgacatt tataactaca tgtattattg gaattataac attaatttta tatattataa
    49921 gaagaaaata tgtaaatcaa atagaaaata ttgcatattt agatagtata acaaatggta
    49981 taaattcaac taagtttagt atgctagtca aacctttaat ttcagaatca cctgatagta
    50041 cttatatgat gatagcaatg aatataaaag attttaagct aataaatgat tgtttcggta
    50101 gtgaaaaagg aaatatgaca ctaaaacatc tttacaatat tttgtataaa aacattgatg
    50161 aaaatgaaga atttgtgtgc cgtcatgatg cagacctttt ctatttgctt attaagaata
    50221 gaccagtgtt agaagccctg gagttattat ataaaataga agctgacaca aattatttta
    50281 ataaaaatag ggaaaatcca tactttttaa gactatcagt aggtatttac acaattgaaa
    50341 atcataatga agatttaatt acaatacaag accatgcaaa tacagcaaga aaaagcttta
    50401 ataaaactca tcaaagtgat ttttcttttt atagtgatat agaaagaaaa cgattaatat
    50461 ctgaaaaaga aatttcaaat ttaatggaaa aagcccttga aaataaagaa ttttttatgt
    50521 gcttacaacc taaaattgat ataaaaagtg gaaaaattag tggagcagag tctcttgtgc
    50581 gttggaaaaa ttcagaaaag ggcataattt atccaagtaa ttttattcct cttttcgaaa
    50641 aaagtggatt tatatgtaag ttagatttat atatactaga agaaacatgc aaattgattt
    50701 ctaagtggat aaaagaaggt aaagaagtgt tgagaatttc tgttaatgta tcacgtcaac
    50761 atttgaatga taaattgttt ttagaaaaat ataagcatat atgcaataaa tacaatgtac
    50821 caacatgtct gatagattta gaacttaccg aatctatttt cttagaaaat ccagaagcta
    50881 tagatataat agaggatatt cattctaatg gatttaaatg ttctatagac gattttggat
    50941 ttgggtactc atcattaggg atattaaagg attttaaagt tgatataatt aagttagacc
    51001 gttcattctt tgttagcaaa aataatatag accgtggtaa ggtagttatt aagtctatta
    51061 ttgaacttag caaaaggcta ggtatgaaag taactgctga aggaattgaa gaattagaac
    51121 aagttgagtt cctaaaaaat gtaggatgtg attatattca aggttatgtt ttttctaaac
    51181 cattattaat ttctgatttt gaaaattttg catatgaaaa taataaaatt aaaaatatcc
    51241 attattaaat gtacaagata aaaaatttag gcaagttata taattaaaaa tataacttgt
    51301 cttttttatt tatatattta ataaaaatat atttgcagat tttgtaaaaa taattttcaa
    51361 atgttgtaag ttgtggctaa agctttattg tattattctg aatatagaaa gatagttact
    51421 gtcttagata aaaactgaaa catacataat aatataaaat ttgctatatt aataactcta
    51481 attattttgg aaggagggaa aatatgataa gtgggagaat gttactcatc atgaattttc
    51541 taaaaggaaa aaataagaca agttacaagg atattagcaa acaacttagt atagaagaaa
    51601 gaaaagttag atatgatata aataatttaa atattgtttt gcgttcatta aacaagtcag
    51661 taatacaaaa gatgaacaaa ggtgtgttaa ttattcctga tgacttccaa gtagtatgta
    51721 taaataataa cgaatatgta ttttccttaa ctgagcgagt atctattatg aaaattatat
    51781 caatgtttaa aatagataat ctaaacttag aaaaattgag taaagaattt caggtttcta
    51841 gaagttcaat taaaaatgac cttaatgttt tgtcaagtga attagaaaga aaccaaataa
    51901 ctattactta tgataaatct tttaaaataa gtggagaaga agaccttata tataagcaaa
    51961 gattgaacat attaaaatcg tattcttatc tttttggtaa ggaaaaatct gatttaagtg
    52021 tatttgagaa gtatttagtg aatgtaattg aaaaaatatt caaagggatt tatttgattg
    52081 atatatataa ttggtctatg aatttattat tgcaaatggg atggacttta aatgatgaat
    52141 cttttacatg gtatgtgtca aacattttcc tttttacatg gtatatacat tcagatgaaa
    52201 aacatccttt agaatctgct tcattaagtg agccatgttt tgaaaataag tttgaccaag
    52261 aatttgaaac aattattcaa aaaaagttga ctaaggaaca aatttttctg ttaaagagtt
    52321 ttgtattttt tacaaataaa tatgcaagtt taaacgagga tatggatttg attagtacag
    52381 aaattatagt tcaagaccta atttacaata tgtcagaaat attagagatt agctttaaag
    52441 aagatatgat tctttataaa ggattactca atcatattgc cccattgata gagagaatca
    52501 agcagaatat acagatttat gaggaattac ttcatgtaat accagataaa tatcaatatg
    52561 tacttgaagc tactaaggtt tctattcaaa aaaacagagt tttaagtcaa ataaagaatg
    52621 aaaatgaaat aatacttttg gcaatacatt tcttaggaag tatacataga aatgagagga
    52681 ataactacaa aaatatattg ttagtttgtg gatttggata tggtgtaatt gctatgttaa
    52741 aggatagttt agtaaatgat taccagataa atatagtaga gagtattcca tcatataagt
    52801 tacaagatta taaagaatgg gaaagtattg acttcattat aacaacatca aagatagtaa
    52861 tagacttgcc taaaacaatt attgagataa atccattttt acaagaagag gattatttga
    52921 agtttgaaga aaaagggata aaaagaaaga acgtcttaac taattatatg tcaataaaaa
    52981 aaaggttgga ctttttagaa gaagatgctc aaaaaagagt attaagtatt atatgtcaag
    53041 aacttggata cagtgatgag agaatattat ttagacaact taatttaagt gatttaatag
    53101 ggattgatac cataaggata attgatgaag atatgaaatg ggaagatgct gtaaaaatta
    53161 gttcaaacat acttgctaat tgtgattttg tatcagcaca atatgctgag aatattatag
    53221 atattttaaa aaatgtgggt ttttatgctg taaaagataa cgaatttgct ttactacatg
    53281 gcaatgatag ttcattagtc aaagtaagtt cgataagttt attaatatgt aaagaagcag
    53341 ttagttttgg agataaaaag gttaaaatca tattttgtct agcaagcaga gataaaaaag
    53401 agcaaattcc tgcaataatt aatctaacta aaatggttta taagactaat tttattgcta
    53461 tgttagaaag tgcaaagaca aaagaagaag cagaagtttt aattcataaa tatgagaagg
    53521 aggtcactgt atgaataaat tagttaatgt aaaatgttca tttaaaatac atgctaattc
    53581 aaaagaagaa gctattgtat cgttagttga tgtagtatca aaagaaggat atctaataga
    53641 taaaaatcaa tttttggaag atgttttaaa gagagaagaa acattgtcaa cttatattgg
    53701 acatggtata ggtcttcctc atagtcaaag tgtaggtgtt aaaaactctt gtattacaat
    53761 aggaaagctt gatattccta ttgaatggac agaagaagga gaaaaagtgg atttaatatt
    53821 tttaatatca gtaacaaaag acaatgaaaa taatcttcat ttaaagattt tatcaaaatt
    53881 agcacgttta ttgatgcatg aaagttttag aaatcaaatt agatgttcag atgaacaaac
    53941 tgtttataat cttataaaag aaaaaataga ggaggaagat taaaatgaga attttaaagt
    54001 ttttgcaaaa acatcttatg acagcaacat cttatatgat tccatttgtg gttgcaggag
    54061 gaatattatt tgctttatca gtaactctaa gtggacaagc tgctgttcct gaaacaggct
    54121 ggttggctaa actgaatcaa attggagctg ctggcttggc tttattcatt cctatattag
    54181 gtggatatat agcatttagt atggcagata aaccaggatt agctccaggt atgataggtg
    54241 catatttagc aaaagaagta aatgcaggtt ttataggtgg tatcatagca ggatttatag
    54301 caggatttgt tgttttacaa ttaaagaaaa ttaaattagc tcctacaatg agaactttag
    54361 gttctatatt tatttatcct ttgattggta cattgattac aggtggtata attgtatttt
    54421 taattggaga acctatagct tcttttatga catggatgac aaactggtta aatggaatgt
    54481 ctggtgtttc taaaattcct ttaggtggaa tcttaggagg aatgatagcc tcagatatgg
    54541 gtggtcctat aaataaggtt gctgctactt ttgcccaaac tcaagttgac acacttccat
    54601 atttaatggg tggagttggc gttgcaattt gtatacctcc aattggttta ggattagcta
    54661 cattattgtt tccaaaaaaa tttagcaagg aagaaagaga ttcaggtaaa gcttcgctat
    54721 taatgggatg tgttggaatt acagaaggag ctattccatt tgcaacatca gatccagtta
    54781 gagtaatacc ttgtattatg gctgggtcga ttataggaaa tattatggct tttttattag
    54841 gatgtttaaa tcatgcaccc tggggaggtc tgatagtatt acctgtagtt gacaataggt
    54901 tggggtatat tgcatcagta ttaactggag cagtagttgt tgcagtatta atgaaattag
    54961 taaaaaaaga cgtgaaagaa gatgaagaaa ttgaagagga tttagatgaa tcaattgaat
    55021 taatatttga agaattataa atataaatgg aaggaatttg tataaaaaag taaatataaa
    55081 actataaact taaaggagat aagaatatga aaattgtagc agtaacatct tgtcctagtg
    55141 gagtagcaca tacttacatg tcggctgaat cacttgaatt atcggccaaa aaatttggta
    55201 tagaaataaa ggttgaaact caaggaagct ctggaataga taatgaattg tcacttaaag
    55261 atattgatga agcaacttgt gtaatattga ctaatgatgt tgagattaga aatatggaac
    55321 gttttaaggg aaagaaggta gtaagaatga gtgtatctga gataattaag aaatctgatg
    55381 cattaattaa gaaaataaaa gatacttttc aataaaaatt gatttatttt acatataact
    55441 caaagatgtt tttaaagaaa tttttattaa aagcatcttt gaaaatatct taaaaataga
    55501 ataaaaggag atatagtcat gaaaaaatta ccaataaaga ctgtcgtaca aagattacta
    55561 gacttacaag aagaggggaa aagtgcaact cttttaggaa ttggtcctat gtcaccaaac
    55621 ttgttacaag caagttttga actagcaaaa gatgatgatt ttcctttaat gtttatcgca
    55681 agtagaaatc aagtagatgc agatgaacta ggtggcggtt atgtaaatgg ttggaatcag
    55741 gaaactttta caaaagatat taagaagatt gccgacaaag ttggatttga tggtttatat
    55801 tatttatgta gagaccatgg tgggccatgg caaagagata aagagagaaa tgaccatttg
    55861 tctgttgatg aagcaatgga gttaggaaaa aaatcttatt tagcggacat tgaagcaggt
    55921 tttgacctat tgatgattga ccctacaaaa gacccatttg aaattggaaa agtaattcca
    55981 ctagatgtag tactagaaag aactgtagaa ttaattgagt attgtgaaaa cgagagaaaa
    56041 agacttaatc taccagacat aggttatgag gttggtacag aggaaaccaa tggaggtctt
    56101 acttcaactg agacgtatga aacatttata actagactaa aggttgaact tgataatagg
    56161 ggtttgccaa tgccaacatt tatagttggt caaactggta ctttaactag aaagacagaa
    56221 caagtaggaa cttttaattt tagaaatgct tatgatttag ctcaaatggc taagaaatat
    56281 ggagttggtt taaaagagca taatggcgat tacttagatg atgtaacttt attagaacat
    56341 ataccatctc aaattattgc tacaaatgta gctcctcaat atggtactga agaaactagg
    56401 gcatatttaa aattagcaga agttgagtgt aaattagaaa aagagggcct agttgataaa
    56461 acttctaata tcagacatgt tcttcttgtt aatgcaattg aatgtggacg ttggagaaaa
    56521 tgggtagtag gagaacaaaa aaatctaact actgaagaga tatttaagaa tgaagtttta
    56581 tctaatgaaa tactagatat tgcaggacat tatacattta ataatgatga tgttaaaaaa
    56641 gaaatagaag tgctttatga taatttaagt aagaataata ttgatggtca aagatttgtt
    56701 gtagaccata ttaaacgtcc tttgcgtgat tatgcagaat gctataactt aaaaggtgtt
    56761 actacgagga ttttaaataa ataataggac ttatagtggt gagtattgtt atactaggta
    56821 tttatagtta taattatact taccactatt aaatttagga ggactaatat tttgattaat
    56881 ttaatttttg atgtagatga tactttatat aaccaattaa cgccttttta cactgcatat
    56941 aataaagtgt tttcttcaat aaaggatatt tctattgaag atttatatat gagtagtaga
    57001 aagtatagtg atgaggtatt tcatatgact gaaaatggag aaatgccaat caaagaaatg
    57061 catatttata ggataatgaa agcttttgag gagttgggaa attctattac agaaaaagat
    57121 gcacaaagtt ttcaagatga gtatatatat cagcaatcac aaattacact aataccagaa
    57181 gttgagagga ttttaaattt ttctaaagaa agaaatatta atctaggaat tataactaat
    57241 ggcccatcaa accatcaaag aatgaagtta aagcagttaa atattgaaaa ttgggttgat
    57301 aaaagtaata tttttatttc tagtgaggtt ggattttcta agccagatac taatattttt
    57361 agagtagctg agaatgttat gaatttagat agagaaaata catattatgt gggtgattct
    57421 tatagaaatg atgtattagg tgctaaaaaa gctggttgga agagtatatg gttgaaccat
    57481 agaggacatg aggtagaaga gttgttttat aaacctgatt ttgtaatttt ggaacataag
    57541 gatttgatat ctttatttat aaaaatatgt agttataaaa atatgtagta aaaaaatgtt
    57601 aataatagaa ttgtataaaa taattaataa taactatata aaattatatg tttagattgt
    57661 gagcaatcta ttttatgtta aaaatagatt atttagaaga aggggaaatc ttaaaaaaat
    57721 ttgaatatcc cctttttatt atttaattaa aatgaaatag ttagaaatat attttattta
    57781 gtttagtcaa taacattttg ggattcttta taactacatg ttaactgttg aataggctta
    57841 tcatatggtt taacccatcc tttattaata cttaattctg taagtgctgt gtgaccttct
    57901 accatttgag ttagtgaagc tgaatatata gctcttaatt caggtgtact acttgttaat
    57961 gcagaattaa gatacatatt ggcagatgct ttagcagatg aaagcatact taacattatt
    58021 actttatcgt ctatataagt attgttctta attagatttt ctatcatatt tctcatgtta
    58081 tctatacctc ctcagaaatt agtatttcat tttcaactat aaattgttgt atagctttaa
    58141 ttcttccttc tgttgctaat atactagatt ctgattgtct ttttaggtct tcatctgata
    58201 ttaacatatt tattgctctt tgcataagta atccgtcaga ctccattttt ataactgctg
    58261 ctaaagatat tttttcagtt tctgaaagtg ttctcattta atcatctcct atattgtaat
    58321 ttatgcttta atagtatgtc tttcttttca aggaaataac cattacactt ttttacagta
    58381 ttttatattc tctttatatc aaagtttagt caacttaata tattaatata attttgtagg
    58441 atatttatca ttaaatatct ataaaataaa ttatttgaat attcataaat caaaatttat
    58501 ttgtatgtac ttcttcaaga gtcaatatga attttttcaa aaaattaatt ttgatgataa
    58561 tcattaaggg ctatattttt cctaaagttg tgattatcat tattaattta ctaaaatact
    58621 ttaatgaaaa atagctaact ttaattgtag gatattctta atatatttga aataaataaa
    58681 aatattgaag gatataatat tcaattggta tataaataat aaatgatagt taagatttac
    58741 cttagaggct aattaggtgt tcagtcaaaa ttaatgcctt tagaatacaa atgtattcta
    58801 aaggcatttt tactatgtat tttcatttat attactaaac attatctatt tttatataca
    58861 tttctatgta ttttattttc atcaaatcgg tctataaatt catttttttc ttcactatat
    58921 ccaatagata taagtgcata aggaactaat tttactggta agtctaaaat ttgtttaact
    58981 ttatttacta ctttattttt aggaaatact cctgcccaac aagcagctag accttgatta
    59041 gtaacttcta ataataaatt ttgtgtgcaa gcacctaaat cttgtatcca tttaccaggt
    59101 tttaagaatt tatctctatt tccaagcact actatacata atggtgcaaa ttctatatgc
    59161 tttgctctat gctgtgactt tgagagctct ttcagcagtt ccttatcatc tactataata
    59221 aattcccaag gttgagcatt ttttgatgaa ggtgcttgca tagctgattt tagtatttca
    59281 gttattttat cttcttctat atttttatct atatatgttc ttattgaacg tctatttttt
    59341 ataacttcta acatacagat tctcctttaa ataaaattat ttctatttat ataatatcat
    59401 tactttaagt tttagctatt acttatataa agaataaact ttgtgttggt tttatctaag
    59461 taaaagtaac attcagaact aaaaaacaag actataaatc caagatatta attaaaaaag
    59521 aagtaataaa aaataatata caagatttaa aaaagagtat tgagcttaaa atttaattag
    59581 aaaaccaatt ttgagataat ctgtttttta ttttaacaaa aaaacataaa taaagttcga
    59641 tacgtagcga atgaaaaaaa tacaagaaat atttttttta aaaaatttca aaaaagagtt
    59701 gataatatat gtatattaat ataaaattta aggtgtataa ttcgtataat aatacgaatg
    59761 atttgtagtg taaaataact tataaacgga gaggggaagt ctaatgaaag tagcagtagt
    59821 tatgggttca aaatcagatt atccaaaatt agaagaaggg ataaaactgc ttgaaaaata
    59881 tggaatagag gttgtagcaa gagcattatc agctcataga acaccagaac aactttcaat
    59941 attcctaaaa gaaatagaag atgatactga tgtaataata gcagcagcag gaaaagcagc
    60001 acacttacca ggtgtaatag cttcacaaac attaattcct gtaataggat tacctattaa
    60061 atcatcaact atggatggac tagactcact tttatcaata gttcaaatgc caaaaggaat
    60121 cccagttgca acagttacaa tagacttagg tttaaacgca gctttattgg cattacaaat
    60181 aatgacttta aaatacccaa aattaaaaga ggatttgaaa tcatatagag aagagatggc
    60241 acaaaaggtg ttagaagacg acaagaattt aagggggtag cagaaatgtt attatatgaa
    60301 ggaaaagcaa aacaagtata ttctacagat aatgaaaatg aatatgttgt ttattataaa
    60361 gatgatgcaa cagcatttaa tggagaaaaa aaagcagaaa tatcttcaaa aggtatacta
    60421 aataataaga tatcaacaat aatctttgaa atgttaaaag aaaataatat aaatactcac
    60481 tttataaaaa gtttatcaga tagagaaatg ttagttaaaa aagtagagat tttaccatta
    60541 gaagtaatag taagaaatat tgctgctggt tctatctgta aaagagttgg tcttgaagaa
    60601 ggtgtagttt tcgatgagcc aatttttgaa ataagttaca aaaatgatgc ttatggtgac
    60661 ccaatgctaa atgatgatta tgcagtggca atgaagttag caactagaga agagttaaaa
    60721 ttcttaagag aagaaacttt aaaaataaac gagttactaa aagcattttt cttaaaatta
    60781 aacctaaagt tagttgactt taaaatagaa tttggtaagg attctgaagg aaatataata
    60841 ttggcagatg aagtatcacc agacacttgt agactttggg atgtaaatac aaatgaaaag
    60901 ttagataagg acagatttag aaaagacctt ggagaccttg tagaaggtta tacggaagta
    60961 ctttcaagaa tgaataataa ataggaggca aatgtatgtg tggagtttta gggatttact
    61021 ctaataaaga tgtaactaaa gaactatatt attctttata ttctatgcaa cacagggggc
    61081 aagaaagctg tggtttagct cttttagatg atggagaaat taagtacaaa aaagatatgg
    61141 gattagttgg agatgttttt aaggaaaatg aattatctaa gttaaaagga aatataggga
    61201 ttggacatgt tagatattca acagctggag gaagtcatgt ttctaactgt caacctttag
    61261 ttggaagttg tagaaaaaga caattagcca tagctcataa tggaaatcta gttaatgcaa
    61321 attatttaaa agatatgcta gaagaagatg gatatatgtt ccaaactaat tcagatacag
    61381 aagtgatttt atatatactt gctagatatt acaaagggga tatagtagaa agtttaaaag
    61441 tgacaatgga ttatataaaa ggtgcatatg ctcttgtaat aatgagtcaa gaagaattgg
    61501 ttgcagttag agacccacat ggattcagac ctcttgtact tggtaaaaag ggtgatgaat
    61561 atatatttgc atcagaaaat tgtgcaatag atatacttgg cggagaagtt ataagagatg
    61621 tagagccagg agagataata gtagtcaaag atggagaact aaaatcatat ttttattcag
    61681 aaaattataa accagttaag aaaagttgta tatttgaaca catatacttt gcaagaaatg
    61741 atgcaactat agacaatgta aatgcatatg aatttagaat taaatgtggt gagagattag
    61801 ctcagaatga aactgtaaag gcagatatgg tagttccagt tccagattca ggttggccag
    61861 gagctattgg ttatgcaaat gctagtggat taaaaataag tgaaggctta gttaaaaata
    61921 gatatgtagg aagaacattt ataaaaccta cacaagaaga aagagaaata gcagtaaaaa
    61981 taaaattaaa tcctctttca acaataataa aaggaaaatc tataatttta gtagacgact
    62041 caattgtaag aggaactaca tctaaacaat tagtaaaatc tttaagagaa gcaggagcaa
    62101 aagaaattca tcttagaata acttctcctc cagtagctta ctcttgttac tatggaatag
    62161 atactccaaa tcgctctaaa ttaattgcat caagtaacaa cgtagaagaa atgagagaat
    62221 atattggatg tgatagttta aaattcctag atatagaagg aatgttagat gcaacagaac
    62281 ataagtctac tttctgtaaa gcttgttttg atggagaata cccagttaag aaaattgata
    62341 aggaggaact actttcatgt taacatataa agaatcaggt gtagatatag atgaaggaaa
    62401 tagagcagta gaccttataa aaggtaaaat aaaaggaact tatgatggaa atgtagttgg
    62461 agatttaggt aacttcagtg gattatacag tttaaaagat tttgtaggta tgaaagaacc
    62521 agttttgctt gcatctacag atggtgttgg gactaagtta aaaatagctc agatgatgga
    62581 caagcatgat actgttggaa tagatttagt tgcaatgtgc gtgaatgatt taatttgtca
    62641 aggagcaaaa ccattatttt tccttgacta tatagctctt gggaaattag tgcctgagca
    62701 tatcgaaaaa atagttggtg gaattgcaga tggttgtaaa atgtctggtt gtgcactaat
    62761 tggtggagaa actgctgaaa tgcctggaat gtatggagaa gatgactatg atttagcagg
    62821 attttctgta ggaatagcag acaaagaaaa gattgtttct ggaaacaatg ttaaatcagg
    62881 agatgtattg gttggtatat cttcaagtgg agtacacagc aatggatttt cttttataag
    62941 aaagatattt ttagaaactt acaattataa aatggaacaa tatgttgaag aactaggaat
    63001 gacagttgga gaagcacttt taacaccaac taaaatatat gttaaattag ctttagatgt
    63061 attagctaaa catgacataa aagctatagc tcacataact ggtggagggc ttatagaaaa
    63121 tataacaaga gttataccta aagggttagg actagatatc aataaaaaat cttgggagaa
    63181 gcctcctata tttaaaatga tagaaggttt taatgctgtt gatgagagag aacttcataa
    63241 gagttttaac atgggtattg ggctagtttt aatagtagat aaagaaaatg ctgatgatgt
    63301 tgtaaacttt ataaataata gagaaaatga caatgctgct tatgtagata aaaaatacag
    63361 tgaattatta gaagataaag cgtatataat tggtgaagta gtagatagtc atgaaggtgt
    63421 agaattatgc taaatatagg agttttaata tctggtggag gaacaaattt acaagcagtt
    63481 atagatggca ctgagtctgg agaaataaaa ggtcaggtta aagtagttat ctcaagtaag
    63541 caaggtgctt atgggctaga gagagctaaa aatcataaca taaaagcaat ttgtgaaact
    63601 gatgaagaca agataataga gattcttaag gaaaataaaa tagatttagt agttttggct
    63661 ggttatttaa aaataatcag cccaaagctg gttaatgagt ttagaaacaa aatgataaac
    63721 atacatccat cattaattcc ttcattttgt ggagctgggt tctatggaga aaaagttcat
    63781 caaggtgtta tagattacgg agctaaagta actggtgcta cagttcattt tgttgatgaa
    63841 ggtgctgata ctggaccaat cataatgcaa gatgtagtta aggtaaatca agatgatgat
    63901 gcaaagacac ttgcaaaaag agtgttagaa gttgaacata ggattttaaa agaaagtata
    63961 agtctttttt gtgaaaataa attaaaactt caaggtagga gagtgtttat aaatgagtaa
    64021 gagagcttta ataagtgtaa ctgacaagac tggtgtagtg gaatttgcta aggagttaaa
    64081 taagttagat tatgaaatta tatctacagg aaatacattt aaaacattaa aagaaaatgg
    64141 tgttaatgta atgcaagttg aagatgttac aaattttcca gaaatattag atgggagagt
    64201 aaaaacatta aatccatata tacatggtgg tatactttat aaaagagata aagaatctca
    64261 tgtagaaact gtgaatgagc ataaaataca ttcaatagat ttagtagctg taaatctata
    64321 tgattttgaa ggaactttaa aagctggaaa aagtcatgat gaaataattg aaaatataga
    64381 tattggtgga ccatctatga tacgttctgc tgccaaaaac tataaagatg taatagtagt
    64441 agtagatata aaagattatg attctataat agaaaaatta aaaacagata caatgacatt
    64501 agaagacaga aaaaaattat catataaagc tttctcaact acaggaagat atgatgcgtt
    64561 aatatctagt tattttgctg gagaagttgg agatacatat cctgacatat taaatttaac
    64621 tttccaaaaa gaacaaactt taagatatgg agaaaatcca catcaaaatg gtttcttata
    64681 ttcacaatca aatgcaaaaa atccaatctt aaattatgag caattaggcg gtaaagaact
    64741 ttcttttaac aatttaaatg atttacatgg atgtttagaa gtaatgagag aatttaaaga
    64801 tagtgaagaa gtagtttcag tagctataaa acatgctaat tcatgtgggg taggtctagg
    64861 aaaagatgct tttgaagcat atacaaaatg ttatgaagcg gataaggttt caatatttgg
    64921 aggaatagta ggaataactt ctactataga taaagctaca gcagagaaat taaatgaaat
    64981 attcttagag atagtagtag catatgattt tgagccagaa gctttagagg tacttaaaca
    65041 aaagaaaaat ttaagaatat taaaattagc taagatagaa gatagtttac aaccatatga
    65101 aatgaaatat ttagatggaa aattattaat acaagataga aataatatat tagcagaaaa
    65161 aagtgaaaat gtaacaaaag caaaaccaac agatgcacaa cttaaggaca tggaatttgg
    65221 tatgagagta gtaaaaaata tgaaatcaaa tgcaattgcg atagtaaaaa atggtcaaac
    65281 tttagcttta ggttgtggac aaacatcaag aatttgggca ttaaaaaatg ctcttgaaaa
    65341 taacaaagat aaagatttta caggagctgt tttagcgtca gatgcatttt tcccatttga
    65401 tgattgtgta acattagctc atgaatatgg aatatcagca gtagttcaac caggtggctc
    65461 tataaaggat aaagattcaa tagaagcttg tgataagtat gatatggtta tggtatttac
    65521 aggaataaga cacttcaaac actaaggagg atattatgaa gatattggtt gtaggcggtg
    65581 gcggaagaga gcatgctata tgctggaaac taagcaaaga aaaaaatgta gaaaaagttt
    65641 attgcgcgcc aggtaatgca ggaattacaa atgtagcaga atgtgtaaat ataggtgata
    65701 ctaatataga agaactttta aaatttgcca aagaaaatga aataggtctg acaatagtag
    65761 gaccagaagt accactagtt atgggaatag tagatgagtt tgaaaaagaa ggattaagag
    65821 tatttggacc taataaaaaa tgtgctcaac ttgaaggaag taaagctttt tcaaaagaat
    65881 ttatgataaa acataacata cctactgcaa aatataaaga atatacaaac ttagaagaag
    65941 ctatatcaga aatagatagt tttggatatc cagtagtaat aaaagcggac ggattagctg
    66001 ctggaaaagg tgttgtaata cctgaaaata gagaagatgc tatagcaact ttaaaagaaa
    66061 tgatgtcaga taagaagttt ggagctgctg gagataaaat agtaattgaa gagtttttaa
    66121 aaggaataga aacttcaatt ctagcatttg tagacaatga tacaatagtt cctatggcaa
    66181 gtgcaaaaga ccataaaaaa gtaaacaact atgagcaagg tccaaacact gggggaatgg
    66241 gaactttttc acctagtgaa atatatacag aagaattagc aaataaagta aaagagacag
    66301 tattagaaaa aactttagaa ggcttcaaaa aagatggact taattttaaa ggtattttat
    66361 ttgttggtct tatgataact gaagatggag aaaaagtact tgaatataat gtaagatttg
    66421 gagaccctga gacacaatct gttttattta gattagaaac agatttacat gagataatgg
    66481 aaactatact agataataag ttaaaagata tagaaataaa ctatagtgat gatgaagctg
    66541 tatgtgttat gcttacatca ggagggtatc cagacagtta tgaaaaaggg aaaattataa
    66601 ctggtcttga aaacttggat gatgatatag tagtattcca tagtggcact aagatgcttg
    66661 atggtaattt agttaccaat ggaggaagag taattggtat aactgcaaag tcaactacag
    66721 ttaaggatgc agcagaaaaa gtttatgaaa acataaagaa gataaacttt gaaggaatgc
    66781 actatagaac agacatagga agataatttt tctaaaatgg aggataaggt atgttgaata
    66841 ctgaaaataa agactcaatg gttagaagag tattagttga aaaaagagaa ggttttgacc
    66901 ttgaggctaa agctttaaaa aaagacttag tagaaagttt acacatagat aatatagaaa
    66961 atttaagaat attaaataga tatgatgtag aaggaatatc agaagaagtt tatgaaaatg
    67021 cagcaaagac aatattctct gaaccaaatt tagatgtagt atattatgaa gaaataccaa
    67081 aattaaatga tgaaagagta tttgcaatag aatttcttcc tggtcaatac gaccaaagag
    67141 gtgattgggc agctcaatgt gtacaaattg taaatcaagg gataagacct gctattaata
    67201 cagcaaaagt ttatatatta tcaggcaaaa taactgatga agagttttct aaaataaaag
    67261 attactgtat aaatccagta gatagtagag aagcatcttt agaaaaacca gaaacattaa
    67321 aaatggaaac tgaaatacca acaacagttg aagtattaga tggatttata gatttagatg
    67381 aaaatggatt aagaacattt gtaagtgaaa aaggattagc aatgacttta ggagacttac
    67441 aacacgttca aaaatacttt aaagatacag aaaagagaaa tccaactata acagaaataa
    67501 aagtattaga tacttattgg tctgatcatt gtagacatac tacttttatg actgaaatag
    67561 aaaatgtaaa gatagaagat ggtaagttta atgatatagt aaaagaagcg tatcaaatgt
    67621 atcttaactc aagagacaat gtatatgtga acagacataa agatatatgt ttaatggata
    67681 tagccactgt tgcagtaaaa gaattaaaga agaatgggaa attaaatgac ctagatgaaa
    67741 gtgaagaaat aaatgcatgt agtataaacg tagatgttga agttgatggt aagatggaaa
    67801 aatatctagt aatgtttaaa aatgaaactc acaaccatcc aactgaaata gaaccatttg
    67861 gtggagcagc tacttgttta ggtggagcta taagagaccc attatcagga agaagttatg
    67921 tttatcaagc aatgcgtgtt acaggaagtg ctgacccaag aacgacttta gaagatactt
    67981 tacctggaaa acttatgcaa agaaaaataa ctacagaagc tgctcatgga tatagttcat
    68041 atggtaacca aataggtctt acaactggac aagttgcaga agtatatgat gaaaactttg
    68101 ttgcaaagag aatggaaata ggtgcagtta tagcagcagt accaaaagag aatgtagtaa
    68161 gagaaagacc tgaagcagga gatgtaatag ttcttcttgg aggaaaaaca ggaagagatg
    68221 gttgtggagg ggcaactggt tcatctaaag aacatagtga agagtcaatc ttaacttgta
    68281 gtgcagaagt tcaaaaagga gatgctccta acgaaagaaa aatacaaaga ttctttagaa
    68341 ataaagaagt tgctcaaatg ataaaaagat gtaatgattt tggagcaggt ggagtttgtg
    68401 ttgctatagg agagattgct gatagtttag atataaactt agacttagta cctaaaaaat
    68461 acgatggact tgatggaact gagcttgcaa tttcagagtc acaagagcgt atggcagtag
    68521 ctataaaaaa agaaaataaa gataaattta tacaattagc agtagaagaa aacttagaag
    68581 ctacacatgt agctacagta acagatacag gatatttaag aatgttctgg aatggaaaag
    68641 caattgtaga tataaataga gagttcttag atacaaacgg agtaaaacaa actactgatg
    68701 tccatgttac taaagtagat gaagaaaata cattctttag ctctaatgaa atagtaaaag
    68761 atgttaagtg tgcaagtatg aaagacaagt ttacaaaagt attatctgac cttaatgttt
    68821 gttctcaaaa aggattagta gagatgtttg ataatacaat tggtggtaat acagtactta
    68881 tgccatttgg aggaaagtat caagcgactc caacacaagg tatggttgct aagataccag
    68941 tacttggagg agaaactaat acttctacaa taatgactta tggatataat ccaaaggtag
    69001 gaaaatggag tccattccat ggtgccttgt acgcagtagt agaatctgtg tgtaaattgg
    69061 ttgctattgg aggaaattat agtacaacaa gacttacatt ccaagagtat tttgaaaaac
    69121 ttggtaacaa tccagaaaaa tggggtaaac cattctcagc acttttagga gcattttatg
    69181 cacaaagtaa atttgagata cctgctatag gtggaaaaga cagtatgtct ggtacattta
    69241 aagatatcga agttccacca acattagttt catttgctgt tgatacagta gatgcgaaga
    69301 aagtagtatc tccagaattt aaaaaagcag actcaaaagt agtaatgtta tgtgtaaaca
    69361 aggcagaaaa tgatgttgta gattttgagg aattaaagag aaacttagac aaagtaagag
    69421 aacttataca tggaaataaa gttttatcaa catatgcatt aggatttgca ggtgtaggtg
    69481 aagcaataag taaaatggct tttggtaata aaataggatt taagtttagt gaagaagctg
    69541 aaaaaacatt tacagatgat aaattatttg aggctagtta tggaaatata gtacttgaat
    69601 tagcaaatga tgatttatgt atgttagaag gatacaatta tgttgtgctt ggaagtacaa
    69661 ctaaagaagc tagtatattt atcaaaggtg aagaacttgc attagatgaa ttatataaag
    69721 cacactgtag tactttagag cctatattcc caactaaaac agaagaagta aaatcaaaga
    69781 tagagactat aagttatata tcacaaggag aagctaaaaa atcatcatta agtatagcta
    69841 ctccaagagt atttatacca gcatttcctg gaacaaactg tgaatatgac tctgcaagag
    69901 catttgaaag agtaggagct aatgcaaaca taagagtatt caagaattta acttataaag
    69961 acatagaaga ttctatagat acaatagtaa acgaaataaa atcttctcaa ataataatgt
    70021 taccaggtgg atttagtgct ggtgatgagc cagatggttc tggtaaattt atagctactg
    70081 tatttagaaa tcctagagtg caagaagcta taaatgaatt tttaactcaa aaagatggac
    70141 taatgttagg tatctgtaat ggattccaag tattaattaa attaggatta gttccatatg
    70201 gagaaataag agttccaagt gaaagtgctc caacacttac ttacaataat attggtcgtc
    70261 atcaagctaa gattgctaga actagaattt catctaataa atctccttgg ttagctcaaa
    70321 ctaatgttgg agatattcat aatatagcaa tttctcatgg agaaggtaaa tttgttgcta
    70381 gtgaagatgt tatgagagaa ttaattgcta atggacaagt agcaactcaa tatgttgact
    70441 ttaataatga agctacttat gatattgagt ttaatccaaa tggttcattc tatgctgttg
    70501 aaggtataac tagtgctgat ggtagagtgt ttggtaaaat gggacattct gagagaattg
    70561 gtgaggaagt atttaagaat attataggtg aaaaagacca aaagatattt gaatctggag
    70621 ttaaatattt tagataaagc tttgatgttt aattgatagc tagaatatat aatttagata
    70681 tttagattta aagagatgta ataatatgat gataatcatt taatattaca tctctttttt
    70741 atttatctaa gaaataataa gttcaaccta agttaaaata caagctgtgt tataattaat
    70801 tactaagtaa aattaaatat ttattggagg gcaacataat taatgaaaat attaataaca
    70861 gggtctaatg gtcaattagg aaaagaattg gttagccaat tagaagcaat caatcaaagt
    70921 ataaatcaac caaaatacgt tatattagct acaacaagaa atgatttgga tatatccaat
    70981 cagactaata tagataattt tattttgcat aataaacctg atgtaattgt aaactgtgca
    71041 gcatatacaa aggttgatgc atgtgaagat aatatcgaaa ttgcgtataa aataaatgcc
    71101 ttaggagtga gaaatttagc aatagcatca gaaaaagtta atgctaagct tgttcacata
    71161 tcaactgact atgtattcaa tggtttttct aaatatccat atagggaaga caataaaact
    71221 gaacccaatt ctgtgtatgg aaaaagtaaa cttatgggag aaaagtttgt tgaacaattc
    71281 tcacataagt actttatatt gagaacagca tggttatatg gtaatgggaa taattttgta
    71341 aagactatga taaaactttc tttagaaaat aaagaggtta atgtggttaa tgaccagttt
    71401 ggaaccccaa caagtacagt agacttagca aaaattataa taagaatcat ggaaacagaa
    71461 cattatggag tttatcatgc tacatgtgaa ggtgagtgta gttggtatga ttttgccaaa
    71521 aagatatttg aattaaaaaa tatagatata aaagtaaatc caattaagag taacgaattt
    71581 aaatgtaagg ctcaaagacc actatattct gtattggata attttatgtt gaagttaatt
    71641 ggtttaaatt cttttagaaa gtgggaagaa tccattgaag aatatttaga aagatatgat
    71701 ataaatgaaa agtaaatgta ttatttttag aaaagaaaat aagatattat aaaaaatata
    71761 aatatttctt ttatttatcc gataatcata atatgacaaa aacaaattta aggatggaaa
    71821 aagatgaaag gaattatttt agcaggaggg tctggtacaa gactatatcc tataacaaaa
    71881 tgtatatcaa aacaaacact tccaatatac gataaaccaa tgatatatta ccctatgtcg
    71941 gttcttatgt tggcagggat acaagatata ttaataatat ctacaccaag agatataaaa
    72001 gcatttgaag aattatttgg agatggaagt tcactagggc ttaaaataac atatgcaatt
    72061 caggagaaag caaatggaat tgcagaagcg tttataatag gagaagaatt tataggaaat
    72121 gacagagtgt ctcttgtatt gggggataat atattttatg gatatggatt tagtgaaagg
    72181 ttggagaatg cagttaaaag aaaaggagca actatatttg ggtatcatgt aagtaatcca
    72241 aattcgtttg gagttgtaga atttgataag gattttaatg tattatcaat agaagaaaaa
    72301 cctacagttc ctaaatctaa ttatgctata ccaggattat atttttatga taatgatgtt
    72361 gtagagatag caaagctagt tgaaccatca gatagaggtg aattagaaat aacctctata
    72421 aacagtgaat atctaaaacg aggaaaacta aaagtggaac ttctaggaag aggtatggct
    72481 tggcttgata ctggtacaca taaaggtcta ttggatgctt ctaactatgt tgaagtggtt
    72541 caaacaagac agggactgta tatagcatgt ttagaagaga ttgcatatac aaaaggatat
    72601 ataagtagag aacaattaat gaaactagcc aagccactga taaaaactga atatggtcaa
    72661 tatctattaa aattggctag tgaagatatg caatatggta gataaaattt attataaatt
    72721 ttattaaggg agtttgttat aatgggaaaa atcaatgtta taaagactaa aatagaagga
    72781 ttatatatag tcgaaccaaa tgtattttgt gatgaaagag gatattttat ggaaagctat
    72841 aataaaaagg attttataga gcagggtctt gatatgtgtt ttattcaaga taatgagtct
    72901 agctcaagaa aaggtgtttt aagaggaatg cattttcagg ttagatatcc tcaaggaaaa
    72961 ttagtcagag ttacagaggg agaagttttc gatgttgcag ttgatttaag aaaagattca
    73021 cagacatttg ggaaatggga aggtgtaata ttgtctgata agaataaaaa acaattttat
    73081 attccagaag ggtttgcaca tggattttta gttttatcag aaaaagcagt atttaattac
    73141 aaatgtacaa actattatta tccagaattt gagcatgggt ttatatggaa tgacaagcaa
    73201 atatctattg agtggccttt aaaaggaatt gaagaaatat ttttatcaga aaaggacaaa
    73261 aaacaaaaaa gttttaaaga tatttgtata agacgttaat aaaaatttat tagaattaac
    73321 atttaggaga aaaaatatga aaaaaatact gataactgga ggagcaggat ttattgggag
    73381 taactttgta cattatatgc ttaacaagta tgtagattat tttattgtta acctagactt
    73441 gttgacttat gctggtaatt tagagacatt aatagaaata caagacagtt ccaattataa
    73501 atttgttaaa ggagatattt caaataggga acagatgtat aagctatttg aagaagaaag
    73561 gtttgatata gttgttaact ttgccgctga atctcatgta gataggtcag ttgagaatcc
    73621 tgatttattt attaaaacaa acattatagg aacacaagta cttttagatg catctataaa
    73681 atatggagtt aaaaggtatc atcaaatatc tacagacgaa gtgtatggtg atttaccaat
    73741 tgatagaaag gatttattct ttacagaaca atctcctatc aatccaagtt ctccatattc
    73801 agcttctaaa gcatcagcag atttgttggt aagttcttat tatagaacat atggattgtt
    73861 aacaactata tctaggtgtt ccaacaatta tgggccatat cattttcctg aaaaattgat
    73921 acctcttatg attttaaatg ctttggaaaa caaacaattg ccagtatatg ggaatgggga
    73981 aaatgtaaga gattggttac atgtatatga ccattgtact gctatagact taataataca
    74041 taaagggaat ataggggaga tttacaatat aggaggtcat aatgaaagaa gtaatttaga
    74101 agtagtaaaa atgatattaa atcttttaga taaatctgaa gagttaatat cctatgtaaa
    74161 tgatagacct ggtcatgatt taagatatgc tattgatgca actaaaatag agaatgagtt
    74221 aggttggaag gcaaaatatg actttgattt gggtataaaa gaaactgtta agtggtatat
    74281 agaaaatgaa tcttggtgga aagctgtttt atcagtgtaa ctttgaaatt tataaaattt
    74341 agaaaggggc gttttatatt gaatgagata agttcactaa ttaatatatt agcattgact
    74401 caattatctg gtagtaatac tacaaatcaa tgtaactgta catataatag ttcatctgga
    74461 tttgatatga ttatgatgac cttgttaaaa gcattatcac aaaataatca acagacttct
    74521 aatggctaca atttatcgtc taattctgag aatttatttg acgaactcgg cagtgtagta
    74581 aataatacag ctagtagatt tatagatgtt gatacaaaag ataaaagtgt aaaatcaaga
    74641 attgaaaatg ctatagagca agcatcaaaa aaatataatg tggattcgaa tcttataaaa
    74701 gcaataatta aagttgaatc ggattttaat ccaaatactg tttcttctgc tggtgctaag
    74761 ggtcttatgc aacttatgcc agaaaattgc agagacttgg gggttacaga cccttttaat
    74821 atagagcaga atatagatgc tggaactaga catattaagg aatacattga tatgtttgga
    74881 gggagcatag aaatgggatt gatggcatat aatggtggtc ctggaagaat gaaaagtaga
    74941 ggagtagaat caatctctga cctgtataaa atgccaaaag aaacacaaaa ttatattcct
    75001 aaggttatga aatattatag agggtaggct ttattatggg gataaatata gataagctaa
    75061 acataagtcc aagtataaat atggaggtta aaaaactaaa agagagtaat aaattttctg
    75121 acaaattaaa ctctttaaaa caatcttctt cattggaaga tataaaacga aatttggaaa
    75181 gtgtaaaaaa ggcaggagaa aggcttgtac ttactcaaaa ctatggcgac attagtatat
    75241 ataaaaatgc agtaaaagaa tacctaaaat ctgttgtaga taatatgtat tcacttgata
    75301 aaaatagtag cttttgggag catcagtatt ataagaatgt aaagattgtt gatagtaaac
    75361 ttgaggatat gactagtaag ttaattagtg aagaaaaaga aaacatagat attgtttcta
    75421 ctgttgatat gatacaaggc ttgttgatag atatgtatag ataaggttat acaaggagaa
    75481 aagttttatg aatagtaaaa aagaggatat atatgaattg aattttgggc aattaataga
    75541 agaaaaatct ggtgttatag aagaaaatca aaatgttttt aatgcaaaag taaatgtagc
    75601 tgtttctata ggaaatacaa cagaaacaat aaaaaatata ttagatttaa aagaaggctc
    75661 tataataaaa ctaagtaaga atgtggatga aaaattagat atatatgcaa atgatagatt
    75721 gtttgcttat ggagaaagca ttattacaaa tgagaagtta tctgtaagat tatctaaaat
    75781 agaagattca gatgtaaatt agtattttaa atagtatccc tttaggctat gatgtatgag
    75841 tttagctaag gggatatttt tataaaaaat ttaaaatatg cgtgaattat ataaatgttt
    75901 ttattttatg agcgataatt aaattataag tatgtaattt tggaggtgaa actatggata
    75961 ttaaaaatgt aagttcaaat attgtagtga ataattattt aaagaataca tctggtgtaa
    76021 aaaaagtgga agaagttaaa aaaattaata aaacagacaa gatagagcta tctaaatttg
    76081 caaaggaaat ggcaagtgtg tcaaatatga gtgatgagaa tattaggaat aaaaaagtcg
    76141 atgaaataaa aaatgcatta gaaaatggaa cttacaaaat aaaaccaaaa gaaattgcga
    76201 aaaaaatgat agaggatatg cgaggataaa gtcatgatta cagacttaaa agttataata
    76261 tatgaagaaa aaaatataat tagtaagatg atggaattat taaaagaaca atttgattat
    76321 atagttgaaa aagacttaga aaatttaaat atgttaaatc ctaaactaga agatattagc
    76381 agggagcttg catccataga aataaagaga agacaacttt ttggtgatga tatttcaatg
    76441 agtgaagttg ttgaaaatag taatgataga tatttaaaag aaatatatac agacttgaaa
    76501 cacattcttg ctttagctaa aaatcaacaa gaatcaaatg attctctaat aaagaaagaa
    76561 cttattttta cgaaaaaaat gattaatttc ataaaaccag ctgataagca aactgcaact
    76621 tataattctt atggaaatat tagaaaataa atattaggag gagaaatatg gcaggattat
    76681 tttccatttt aaatacagct aattcaggaa tgaatgcgca ccaaaaagca atacagacaa
    76741 tttctcataa tataagtaat ctagatacag acggttattc taggcaaagg actgagtttg
    76801 ctacaaatag tccaatgtat atgcctagtt tgagtaattc aattgcaaga ggacaattag
    76861 ggactggagt acacgtaacg gatgtaacaa gagctagaaa tagtttttat gattaccaat
    76921 ttagagcaga agctcataag tatggtaata cagtttcaaa gtatgactat tataatacta
    76981 tagaaactat aataaatgaa ccatcagact atggaatatc tgcaggtata gacgactttt
    77041 ttaaaggatg ggaatcatta gcaaaggata taaatagtga tagtaaaaaa agtctagtgg
    77101 tagaaaatgc atcaaatcta gcaactttaa taagtgaaag ttataagaag cttaataagt
    77161 taaagggaga tatagacgat aatataaact ctgaaataaa acagataaat gacatgttaa
    77221 aaagtcttga agatttgaat aaatctattg atgttatatc tggttctggc tctactccaa
    77281 atgatttact tgatgaaaga gatagaatat tagatgactt aagctttaaa ttagaccttg
    77341 aaaatagcga tgttaaaaat atgctttcag atggtaaatt agaacttaat gaattaaaaa
    77401 atgcagatgg aacttggaaa acaggtgtat caggaacctt acaaggcttg tttgaaatgc
    77461 atggtaagat tgatacatat aaaagcgatt taaaagatgt atctgatggg ttagctaagc
    77521 agataaatga tgtttataat acatctgctg gaataacagt aacagatttt tttataactt
    77581 caaatgtaga tggtgaagat atcataaagg taaatccagc tataaagagt aacccaaatg
    77641 aattaaaact tactgctgat gaggcttcaa agattgctaa gttaaaggat gaaaaaatag
    77701 atattggggt ggctggtgga aaagtaagta caataagtga ccactataaa gcctttgcag
    77761 aatcagtagg tttagattct caaaaagtga atcaagatga agtgaatcaa cgtaaaatta
    77821 taaataatat tgataactca cgaatgagtg tttcaggcgt atctttggat gaagaaatga
    77881 cagagcttat aaaaatacaa cgctcctatc aagctagtgc aaaagttatg tcaacagctg
    77941 tgcaactgtt ggatgttgta ataaatggaa taatttaata gaagggggaa tttataatga
    78001 gagttagtac aggtatgatg tctagcaact atctaaactc actacaagat aatctacaaa
    78061 gattagataa ggttaataga caagttaata caacgaaaga aataaacaag ctatcagata
    78121 atccatataa ggcaataaaa atattgaact caaaaagtga aataaaaact atggagactt
    78181 atgttgagaa ttgtaaagat acagggaatt ggttagaaac tactgatact gcattagatc
    78241 agcttggaaa attattatcg gacataaaga aaactttggt ggcaagtggt gatggtgcat
    78301 attcagatga tgagctaaag actcttagta atgaaactaa tgaaaagatg aaagaaattg
    78361 caaatgcctt aaatgcaaca catgaaggaa agtacatatt ttcaggttca aatacaggtg
    78421 taccacctgt tgaatgtata gataatgctg acggttcagt gagcttaaag tttaattcta
    78481 gtttaaatct taataaatta aatgactctt tgagtatgga tatagctcaa ggaataagtg
    78541 tagattataa tgttaaattg agtagccttg gatttgaccc aacaaagact gacccatttg
    78601 aagagttaaa taatatatca aagaaattag caaatccaga tgctgatgct ataaaagagc
    78661 tgacaacaac ttgtttaggc gacatggaac aattaataga aaatacagta aatgttaggt
    78721 ctatatatgg gacaaaagca aatacagtag aggctatgaa ggaaaaaaat gatgatagtt
    78781 tgatacagtt aaaggatatt ttgtcacaaa atgaagaaat agattatgga gaaaaactcg
    78841 ttcaattaaa ggcagcagag ttaacttatc aagcttcact acaaacagga ggaaagttat
    78901 ttaatgtatc tatattagat tacatatagt aaaataacgc agatatgatg aaggttacat
    78961 taaaaaaagg tatattaggt tttgaaaatt taaaagaata tgagctttta gatatagaag
    79021 ataatgattc tttaaaagaa tttaattcta ctgaagaaga aggtatagga tttgttgttg
    79081 tatctccatt tgagattatc aatgaatatg aaatagtttt aaatcaggaa acaatagaaa
    79141 aactagaagt gaaatctcca aaggatgttg tactatttaa tataattact cttggtcaga
    79201 catttgaaga atcaactgtg aacatgaaag ctcctatagt gataaatata aaaactaatt
    79261 ttggaatgca aataatttta caggatgata aatattcaat aaggcatcca ttattgagag
    79321 gtgataatgg atgctagtaa tttcaagaaa aaaagatgaa gcagtactta taggagaaag
    79381 catagaagta aaaattgtag gggtagatgg aaacaatgtg aaactagcta tatcggcgcc
    79441 taacaatata agtatattaa gaaaagaaat atacgaaaaa gtaaagagtg agaatataaa
    79501 agctacaaat aaaaatataa aaattttaaa gtcattaaaa taataagctt ggaggaagta
    79561 atatatgtat ggagaaaatc cttataattc ttataaacaa aatgctgttt ttatggcatc
    79621 aaaggaacaa ttgttactta tgcttgttga tggagcagta aaatatacca aaatagccag
    79681 agcagctatc ttagataaaa atacacagaa agcgcataga gaacttgtaa gagttcagga
    79741 tatatttaca gaactaatgg ttacattaga ccaaaatgca ggacaatggg caaaggatat
    79801 gtacaaagtt tatgattttg taagatatga actttcaaga gccaatatta gaaaagacat
    79861 ccaggtaata gataatgtgt tgcctgtaat agaacaaatt aaagacacat ggcatgaagc
    79921 tgataaaaaa agtaaagaag aaagaagtag gtacaaataa tggaattaaa tttagctgaa
    79981 ttagataagt tatcaaaaga ggaattacta ttgatgcttg tagatggcac agtaaaatat
    80041 accaatatat ccaaagaagc tcttttaaat aacgactatt tgaaagcaca taatgaactt
    80101 ataagagttc aaaatatatt tacagaacta atgactacat tagaccaaga tgcaggtcaa
    80161 tgggcaaagg atatgtataa agtttatgaa tttataaaat ctgaattagc aatagctgat
    80221 gaaaataaag atattaaaat aattgatgat atattgccaa tagtaaaaca aattagagat
    80281 acatggcatg aagtttacaa tcaactaaaa atataattag atggagggat aaaggtatgt
    80341 caagtataag tcctataaga gttacaggtc tttcaggaaa ttttgatatg gaaggcataa
    80401 tcgaagctag tatgattaga gacaaggaaa aagttgataa agcaaaacaa gaacaacaaa
    80461 tcgttaaatg gaagcaagaa atatatagaa atgttataca agaatcaaaa gatctttatg
    80521 ataaatatct aagcgtaaat tctcctaata gtatagtaag tgaaaaagca tactcttcta
    80581 caagaataac cagttctgat gaaagtatta tagtagcaaa aggctcagct ggtgcagaaa
    80641 aaataaatta tcaatttgca gtttctcaaa tggctgaacc agcaaaattt actattaaat
    80701 taaattcaag tgaacctatt gttcgacagt tccctccaaa tgccagtgga gctagttctt
    80761 taactatagg agatgtaaat ataccaatat ctgaacaaga tactacaagt actattgtaa
    80821 gtaagataaa ctccctttgc gcagataatg atataaaggc ttcttatagt gagatgacag
    80881 gtgaattgat tatttcgaga aaacaaactg gttcgtcatc agacattaat ttaaaagtaa
    80941 ttggaaatga caatttagct cagcaaattg ctaatgataa tggtatcaca tttgcaaatg
    81001 atgctagtgg aaacaaagtg gcaagtgtat atggaaaaaa tctagaagct gatgtaactg
    81061 atgaacatgg aagagtaact catataagta aagaacaaaa ttcatttaat atagataata
    81121 ttgactataa tgtaaattca aaaggaactg caaagttgac ttctgtcact gatactgaag
    81181 aagctgttaa aaatatgcaa gcatttgtgg atgattataa taaactgatg gacaaggtct
    81241 atggtttagt tactactaaa aaaccaaaag attatccgcc tcttacagat gcccaaaaag
    81301 aagatatgac aactgaagaa atagaaaaat gggaaaagaa agctaaagaa ggtatactta
    81361 gaaatgatga tgagttaaga ggttttgttg aagatattca gtctgcattt tttggagatg
    81421 gaaaaaatat tattgcatta agaaaactag gtatcaatga aagcgaaaat tacaataaaa
    81481 aaggtcaaat atcatttaat gcagatactt tttcaaaggc tcttatagat gatagtgata
    81541 aggtatacaa aacactagca ggttattctt cgaattatga tgataaggga atgtttgaaa
    81601 agctaaaaga tattgtatat gaatattctg gaagttcaac ttctaaactt cctaaaaaag
    81661 caggtataga aaaaactgct tctgctagtg aaaatgtata ttcaaaacaa attgcagagc
    81721 aagaaagaaa tataagcagg ttagttgaaa aaatgaatga taaagagaaa agactttatg
    81781 ctaaatattc agccttagaa tctttgttga atcagtattc ttcccaaatg aattatttct
    81841 cacaagcaca gggtaattaa ttatggataa attaaaagaa aaattaaatt tatataaaga
    81901 tatatcttta caaattataa atttgattga aaaggaagaa tatataaaga taagtagtaa
    81961 gttaggtgaa agacaagaga ttataaatag tgtaagtgaa attgatagaa atgattttat
    82021 acagctttat aatagaatgg aattaattga aattgatagt aggataagag atattttaca
    82081 aggacaatta ttagaagtaa aaaaagaatt acatgagtat aagcttacta aacaagtgaa
    82141 cacaatgtat tataacttaa atagagaaaa agtaaatatt tttaataaaa aagtataaag
    82201 ttatgtacca tcttgtccga ttatataaat gaagaattaa taaaaaagat taaaagtaga
    82261 aatgacaagg atgtcaacta tactaaggag ggtaaaataa tgagagttaa tacaaatgta
    82321 agtgctttga tagcaaataa ccaaatggga agaaacgtaa atgcacaaag taagtctatg
    82381 gagaagttat cttctggtgt tagaattaag agagctgctg atgatgctgc tgggcttgct
    82441 atatctgaga aaatgagagc tcaaataaaa ggtttagacc aagcaggaag aaacgttcaa
    82501 gatggtatat ctgttgtaca aacagcagaa ggtgcattag aagaaactgg taatatacta
    82561 caaagaatga gaactttatc agtacaatct tcaaatgaaa ctaatactgc tgaagaaaga
    82621 caaaagatag ctgatgagtt gttacaatta aaggatgaag ttgaaagaat atcaagctca
    82681 attgagttta atggtaagaa attacttgat ggaagttcta cagaaataag attacaagtt
    82741 ggagctaatt ttggaacaaa tgttgcagga acaactaaca acaacaatga aataaaagtt
    82801 gctctagtaa atacttcaag tataatgagt aaagcaggta taacaagttc tacaatagca
    82861 agcttaaatg cagatggaac ttctggaaca gatgcagcta aacaaatggt gtctagctta
    82921 gatgtagctc ttaaagaatt aaatacatca agagcaaaat taggggcaca acaaaataga
    82981 ctagaatcaa ctcaaaacaa cttaaataat actatagaaa atgttacagc agctgaatca
    83041 agaataagag atacagatgt tgcttcagaa atggttaact tatctaaaat gaatatatta
    83101 gttcaagcat cacagtcaat gcttgctcaa gctaatcagc aaccacaagg agttttacaa
    83161 ttattaggat aaaataattt tgtatattgg atatagaaga aagggtaagg ctttgcttta
    83221 ctcctttctt tttttacaaa tatacttttg aaaggaaaat atatatgtta cttagtatag
    83281 ttatgattgt taaaaatgaa gaaaaaatac ttgaaaaaac tttaaaatca ttaaccacat
    83341 taagaagttc tatagagagt gaacttataa tagttgatac aggttctaca gatgatacta
    83401 taaatatatc taggaaatac acggaaaatg tgtactttca taattggaat aatgattttt
    83461 ctagtatgag aaatatatca atatcctatg ctaaaggtga atggttactt atattagatg
    83521 cagatgaaat actaattgat tcttcaacta ttgtgaaatt ttttaaagat ggtcttgata
    83581 aaaaatttaa ttcggcctca atacaattaa aaaatcttta ctcatatgat aaaaaattat
    83641 atggatattg ctcagtgctt agacttttta aaaacatcga ttttagatac catggtaaag
    83701 tacatgaaca accaatatac aaaaacccta tatttaataa tgttgctgat tttgaacatt
    83761 atggatattt gtttgaagat gaagaaataa gattaaataa agtaaaaaga aatgaaaaac
    83821 tgttatttga agaattaaaa gagaatgata attctccata tacaaattat caattaggga
    83881 aaaattttat tatattagga aaatatcatg aggctttata ctatcttgag aaatcttatg
    83941 aattatattc taaactagaa tcggcacctg gttacttgat aacaagtctt gtaaaaacat
    84001 atttatattt aggaaagcat aagaagtgtg aaaaattgtg tctaaagtat attaagaaag
    84061 acatgaataa tattgatata tattattata ttgcacaagc acaagtagat ttagggaagt
    84121 atgaaaatag tatagattcg tataagagat atatttattt gttagataat tatgaaataa
    84181 gtacacaagc aaatagttta ttttcagaca ctgatactgt agggcttagg gatgaagcta
    84241 ttattacact gataaagatt tattataaac ttgaaaaata tgagtctgta atttcagagt
    84301 acaataacat tgaggatatg gaaaagaaga agaatgtgta ctttagctta tttatgtccc
    84361 tatacaaatt gaacagattt gaagatataa aaaactatta taaagaagtt tcaaattcta
    84421 aaattgaaaa aaatagtttt tataaaaata tagaagaagt tataaataat attaaagatg
    84481 atgaaaaaga gcatgtatat aaaatccttt gtgacattga aggtaattat ggcattttaa
    84541 atcagataag gataaataaa tgtgtatcta tagataagtg taaagaaata ctcaatgaag
    84601 aaaaagaaat aatttatgca tatattataa aagtagcttt tgaagataag attgatttac
    84661 tagatatttt ttatgaaatg gaatatgtat ggatagagaa atacctaaaa tatcttttag
    84721 cactagaaag aagttttaat ttagtactat ataagtacat aattagtcgt ccgaatacat
    84781 cagatataaa aaagataaga gtatataaag ctatatctaa agtagtttta gaaagtataa
    84841 gtttaagtga tgaaaaatat aaggagattt tttatcttta tataatgtat tcttataagt
    84901 acataagata catatataga aatttaagcg attttgaatt aataaaattt gtttgcaatg
    84961 atttagataa gtttactata gaatttaagc atctacttga cattaaaaat aaagtaaatg
    85021 atgctaatga aaaattagag tatatacata gtatgaggaa attactaaat gagtatcctt
    85081 tttataataa aataataaaa atacttataa gtgaattaga agaaaatata aaagaaagtg
    85141 aagaatttaa ggatttaaaa gatagtttta ttattagtat agaaaatatg attgaaactg
    85201 gcaaaataaa tgatgcgaaa tcattggtag atgactattc aaaaacattt atggatgatg
    85261 taaaaatttt aaatataaag ggaattttat atatgtttga aaataagctt gataaagctg
    85321 attttatgtt aaaaaaggca ttatcattag atgtagaaaa tgaagatact atatataata
    85381 tagaatactt aaaaagttta agataagtca aaaatgggag aattgaagaa tgaatacacc
    85441 aatagtggtt aatgaaaaat ctaaagatat aataaaagat tggcaatata cgtatacaaa
    85501 cgaagatata aaatttacaa gcataataat attgacatat aatcaaatag aatatactaa
    85561 attatgtatt gaaagtatta ggaagtttac cccaaagaat aaatatgaaa taataataat
    85621 tgacaataac tcttctgatg gaacagttga gtggttaaag ggacaatctg acataaaatc
    85681 tgtatataat aacaaaaacc taggatttcc aaaaggatgc aatcaaggta ttgagttggc
    85741 tactggtgaa aacatattgt tgttaaataa tgatgtaata gttactccaa attggcttta
    85801 taatttgaat aaagctttat ggtctcaaga taatataggt gctgtaggtc ctattacaaa
    85861 tgcatgttcg tactatcaac aaattgatgt tgattataaa tcaattgagg atatgtttat
    85921 gtttgcacac aaaataaata catctaatat taacctatgg aaatatagat taaagttagt
    85981 tggattttgc atgttaataa aaaaatctgt gctggataat gtaggggttt tagatgaatt
    86041 attcacacct ggaaattttg aagatgatga tttatctttt aggatgctag agtcaggata
    86101 taagctatta ttatgccagg atacttttat acaccatttt ggaagtgtat cttttaaaga
    86161 aaatcgtaat aaatatacag atataatgta tattaataga agaaaatttg aaactaagtg
    86221 gggatttaat ccagaatata gtggaatgat aagaacagat ttgatttcta aaatagatga
    86281 tagtttggag gcaaatatta atgttttaga aataggctgt ggtatagggg ctactctttt
    86341 agaaataaaa aatatatata aaaatgcatc aatatatgga atagaaatta gtgagtcagc
    86401 aggtaaactt gcaaagtata gtgcagatgt acttatagca gatatagaaa aagtaaagtt
    86461 ggattatgaa aaagattttt ttgattatat aatattggga gatgtacttg aacatttaac
    86521 tgacccatgg aagatagtca atgaactgaa acaatatcta aagaaggatg gttgtttgat
    86581 atctagtata ccaaatatta tgcatgtttc tgttttaaga aaccttgtgt taggtaattt
    86641 tacatatgaa gattcaggaa ttttagacaa gactcattta aggtttttta cattaaatga
    86701 gataacaaaa atgtttaatg atagtaatta cataataaat agtgttacag ctactagtat
    86761 gccactttcg gaaattgata atagattcat tgatacaatg tgtaaggaaa gctgtaaaga
    86821 aatgagacaa cagtacgaat cttatcaata tatagtaaaa gccactaaaa gcatagatac
    86881 taaaagatat tctagtatta gtatggttaa tttaaaatac gctttaatga gaattgataa
    86941 tgaattagat gtagatagta atttaagtta tatatttgat aattataata taactgaacc
    87001 atgttttgtt gatgatattg aatatttagt tgatacgttt gtgataaata aagcaactct
    87061 attaaataga ttaggagttg aggcatttaa cagaggttta ggagatttta gtataaacat
    87121 gtttatgaca gtattagaga tggatagaga tgatattgat tcaatatata atataacaag
    87181 tgtattatgt gaattagaag aatttgatac tgcttacaac ttaattaaaa atagtagcaa
    87241 aaaagtacag agtgaaagtg acatacaaga tatactttat tttattgagg ggaagagata
    87301 tgaataatga taagatatgt tttataacct gtgtaaatga tgaaagactt tatgaggaat
    87361 gtcttgtata tataaatagc ctagacattc ctaaaaactt tagcatagaa acagtagctt
    87421 taagaggagc cgattctatt gcctctgctt ataataaagc tatgagagaa acagattcta
    87481 agtataaggt atacttacat caagatgctt ttataattaa taaaaatttc atatatgaca
    87541 ttttagagat atttaaaaaa aatacagatg taggaatgat tggtgtagct ggagtaaaag
    87601 atatacctgt gaatggaatt tggtgggatt ctgataaaaa agcagggaaa gtatatgata
    87661 gccatacagg taaaatggat atttatgaat ttagtaactt tgaagaatgt tttaatgaag
    87721 ttatggctat agatggatta attatgatta ctcaatatga tgtattttgg agagaggata
    87781 agtttgatgg gtggcatttt tatgatttgt cacagagtat ggaatttaga caaaataaat
    87841 acaaagttat tgtaccaaaa caaaataagc cttggtgtat gcatgattct ggagtagcaa
    87901 atataaataa tggatatgat gaatatagga taaaatttgt aaaagagtac ataaatcttg
    87961 atttatatag agaaaatttt tatgaatttg ataagaagaa agcaagtacc atacttaaga
    88021 gtaataagca tgtaatggat tgtatgaaag aggagcttac agaacaatta agattaaaga
    88081 attataagga tgttttagat attgtttcta aaattgctca tttttctgtt tttaatcata
    88141 ctggcttgta ttcttgtgaa aaatgtgaga gagcattgct agaatgtgca aataatttac
    88201 cagaaataga aaatacgaaa ttatttacaa aaaaagattt aaaaagaaga aaagtattac
    88261 atgttttaag tgaaggatat tcaacaggag ggcatacaag actagttaaa aattggattg
    88321 agattgacaa agattctgtt cattcagttg taactacatg gcaatcagat acactgccag
    88381 actggttatt aaaagcaata gatgatagtg gtggcgaagt tatatctttg gatttaattt
    88441 cagatgatta tttaaaaaga gctgtagctt tgaggaaaat agcttatgac tgggctgata
    88501 tagttatttt atatgttcat atgtgggata caatacctgt tgttgctttt ggagttgatg
    88561 ggaaaatacc tattttacat gttaatcact atgatagtac tttttggtta gggacaagta
    88621 ttgcagatat tgtcattgat tttagcgaag ctagtcaatt aattacatta gataaaagag
    88681 gcatagataa atctgaaata ttaccaatgc cattaaaaga aaaagaagta ttttcaaaat
    88741 ctgaagttag aaaacgatat aatttggagg atgatgtgac aataatattg actattgcta
    88801 gtgaaagaaa atacaatagt gtaaatgata ttaattactt taaaattgct aaaacattga
    88861 ttgaaaatac agataataca attattattg ttgtaggagt tgatacagag aatctctatt
    88921 ggaaaacttt aagtaacgtt acagataata gagttatatg ttttggaaca acagcaaata
    88981 tagacgattt ttataagatt tcggatatat acctagagtc tttcatggta gggagtcata
    89041 cttcaaaatt agatgcaatt ttatatgatt taattcctgt taagtttaaa aatgaagttt
    89101 caccaatttt tacaaatatg tggaatttta tagataagtt tgattataag aatataaaag
    89161 aggttataga catgataaga aggtacaata ctagtgaatt tgacagggat aagataaaag
    89221 aaaaacaatc agaaataaaa cattttgtta tagataaaca ctgtattgaa ataaaaaact
    89281 atatagacaa aatatataaa gaggctaatc atcataaagt taagtatgat ttatataaaa
    89341 atgatgaaat cgaagactat cagctttttg ttgcattata tggttatatg gtaaaaaata
    89401 aaaacatgtc ataggtgata aaatgaacaa tattcatatc aataaatttg aaaaaagctg
    89461 tgaaaaaaac tgggattatt ttgtagaaaa taaatctata aatggtacat ttctgcaaac
    89521 tagaaatttc cttaattatc atgaagaagg aaaattcact gaccactcat taataatata
    89581 taaaggtgaa gaaatactag cagtcgtacc tgcatgtgaa acttatgaaa atggtgaaag
    89641 agtatttttt tctcatttag gaagcacttt tggaggtatt ataataagaa gtggttttaa
    89701 tgatattagg catgtaaatg ctattacaaa taagttagaa acatatttac aggaacaaag
    89761 tttcaataaa gtatatttaa aaaatacatc aagaatattt tgtaaagagg atacttcatt
    89821 actagaatat tttctattta agaataatta catgttttat gatgaattaa gtatgttttt
    89881 agaattaagt aagtataaaa aagatatatt agctaatttt agatatagta aaagaagata
    89941 ttttaaatat tctttgaaga ataatcttac ctttaaaaga ttgtatagtg atgaggatat
    90001 agtttgtttt tttaatttac tttctaattg tttagatagt aaaggagcta aagtaataca
    90061 ttcagtagaa gaacttttgg agtttaaaaa taatagatta aaagatattg tagaatttta
    90121 tgcagtatat attgatgaca ttatgatttg tgggagcatg gtatttaact ttcaagaaag
    90181 agtttatcat actcaatatc tagcatcaaa ttcgacatat aataaatatt atccaatgat
    90241 atttttatac tataatctaa taaaagatgc tttagagaga aattttaagt atctttcttt
    90301 tggaattagc actctaaata gaggcaaata cttagacgag ggtttagcta catttaaaga
    90361 aggttttggt tcaagtgcaa tttgcaacag aacatactat aaaaatataa ataagtgata
    90421 atcatgtttt atagagtttt tagagtatag taaatatcta gtactctaat attacataaa
    90481 aataattagt ttataaagaa ggtttgtata tgaaaagatt aatgatttta ggctcaatta
    90541 agtattttga gaatattgtt atgtcagcta aaaaagaggg aatatacaca attgtttgtg
    90601 ataatagaat tgatactcct gcgaaaaaga tttgtgatga agcaatagat gttgatgtat
    90661 ttgattttga taaaataaaa agtatagcta tagataaaaa gatagatgga attttaactg
    90721 gatttacaga ttctttaatg aaaccatatg tttatattgc aaatgaacta aatttaccat
    90781 gtgtgatttc ttgcaatcaa cttgaatctg taactaataa ggctattatg aaaaaatatt
    90841 ttaaaaataa tgcaatacct acaactgatt attgtattat tgaaagtcta aaagatttag
    90901 aaaaaataca aggattaaat tttccacttg taataaaacc tgttgatggt tatggttcaa
    90961 gaggtgtata ttttgtatca aatatagaag aattaataga aaaatttgaa tattctaagg
    91021 aagcctcaca agatggacaa gtaataattg aggaatttta tgaaagtgag gaaatacaag
    91081 gactagcttg ggttcataat ggagagtcac atgtatttta tattggagat agagagcttg
    91141 taaatataca tacaggaaga gctggaaaac cagatagatt actttatcca tcaaagtatt
    91201 gttttcaata tgaggaagaa ataaaatcta tatatcaaaa tataacacag gcttttgata
    91261 taaaaaatgg acctctttat gtacaaatgt tagtgggagc atatggaata aaggtatctg
    91321 aagtaatgcc aagattacct ggaggttgtg actatatggc tatttctcaa ataacagatt
    91381 tagacatagg aagtttattt gcaaacttta gtgtgaataa tgaagtaaat tttgatgaaa
    91441 taaagaaata taatatgcat ttatcaaaat gtgtatatgc attaccaata tacataagac
    91501 ctggaacaat aaaaaagata aataatatag ataaaataga aaacttagat tatgtcactc
    91561 aatttctatt attagtaaaa gaaggagata caataggatt atatgaggat gagagacagg
    91621 attgtggaag agtttatgga atagcaaata atatatttga tgcaaatata aagaagaaat
    91681 gtattcatga aatgatagaa atatttgatg aaaataatga aaatatgata gaaaattttt
    91741 aaataaggga gtatgataga tatgaagcta ataactcatg aacaaattat gtcattaaac
    91801 atttctcaga aacaaggata tgaatggata aaagaatctt ttttaacaaa aaaagattgt
    91861 caattaccac caaaaataag catggtagaa gaaggtcatg tattttacaa tgtaatgccg
    91921 tccttaaatc ataaccatat gattggtgga ataaaaatgg ttacaagatt gccagggaga
    91981 aatccaagtt taaattcaga tatatttcta tacaatatga aagatgctaa attaaaggct
    92041 attttggatg gtaattatat tacagctttt agaactgctg ctgttgctgg tttggctatt
    92101 gatacttttg ctaaaaaaga ttttaatact atttctatta tgggtttagg tgtaactgct
    92161 tctgctataa tgaatatgct ttcgtatact cttaaagata aaaatataaa tataaagtta
    92221 cttaaatata aagaccaagc agagtcattt ataaaaaagt atgaaaaaaa tgaacaattt
    92281 agttttgaaa tatgtgatac acatgaagaa cttattgtag attcagatgt agttatttct
    92341 actgtgacat atacagatga atatttatca gaatttaaat ggtttaaaaa aggtgcttta
    92401 ttattacctg tacatgttat gggatttgga aatgttgatt atctatttga taaagtatat
    92461 ttagatgatt ataatcattt gaaacatcta gaaaatatag atagatataa atattcttgt
    92521 gaattttata atgttttaag taaacaagct aaaggaagag aaaatgatga tgagagaata
    92581 atatcttaca atataggttt gtcaatacat gatatattat ttgcaaacaa aatttacgaa
    92641 ttgtgtgaaa cactaaattg tgaagagata gaattaaaag aaccaaaaga aaaatattgg
    92701 atatagttta tttcattcat atttacaata atttattgta aatatgaata tgaagtaata
    92761 tattgttaga aaattagcat gaataggata gataaattta tggataaata taatttaatt
    92821 aagttcttat ctattggaaa cgaatatata ggaaatttag ttgcattaga atcaaataaa
    92881 gcaatacctt ttgatataaa gagagtttat tacatatatg atgtaccaaa caatgtaaag
    92941 agaggatttc atgcacacaa aaacttggaa caagtactag tttgcctaaa tggaagtgtg
    93001 aagataaaat gttatgatgg tgtaaaagag agtatattta atttacataa aaatgatgtt
    93061 ggattgtata taggaacggg agtgtggcat gagatgtttg actttgatga aaaaactgtt
    93121 ttaatttcta tagcatctga acattacaat gaagaagatt atattagaga ctataaagaa
    93181 tttttaaagt atttaaataa tatgtagtta ttatacagtt agtgatgtat tttcttaatt
    93241 aaataaattt aagatagcca tatagagaat aaatagatta ggatgtgaat ttattgttgg
    93301 ttaaatttaa taatttatta aaacagttcc aaactcataa agaagaatat gaacagaaga
    93361 ttaaggatgt aatggaaagt ggatattata tccttggaaa tgaagtaagg cattttgaag
    93421 aagaatttgc tagctatgta ggtagcaaat attgtgttgg tttagccagt ggtttagatg
    93481 cacttataat tgcttttaga gcattaggaa taagtgaagg tgatgaagta atcgtgcaat
    93541 caaatacata tattgctagt gttatgggaa tcagcataaa tggagcaaca ccagtatttg
    93601 tagaaccaaa tgaatattat aatatagatt catctaagat agaagaaaag ataaatagca
    93661 aaacaaaagc tatattagta gttcatttat atggtcaagc aagtaaaatg aaagatatac
    93721 aagaattatg tgataagtat aacttgtatt taattgaaga ttgtgctcaa tctcatggag
    93781 ctaaatatga tggaaaaatg acaggaacat ttggtgatat aggttgtttt agtttttatc
    93841 caagtaaaaa tttgggtgca tttggagatg caggagctat agtaactagt aatgaggaaa
    93901 tagctgataa agtgaaaatt cttagaaact atggttcaga aaagcgatat tataataaat
    93961 ttgtcggata taattcaaga ttggacgaaa ttcaggcagg tttattaaga gtaaaactta
    94021 aatatctaaa tgaaattgaa attgaaaaat caaaaatcgt agatagatat cttaatgaaa
    94081 ttaataatcc caaagtcata cttccaaaga tagaaaataa ttgtactcat gtatggcact
    94141 tatttgtttt acaagttgaa aaacgagata catttatgga atacttaaag aaaaatggta
    94201 tagagtctat aatacattat ccgataccac cacatctatc tgaagcatat gcttatttgg
    94261 gatataaaaa ggggagtttt aatatagctg agaactattc agataaagtt gttagtatac
    94321 ctttatttgt cggtatggaa gatgaagaag ttagttatat aattaaaatt ataaatgaat
    94381 attaaactaa tcataataat atcaaaaata aattttctat atatcattta tttaaatttc
    94441 gttaattgac atttttaaat attgatatat tgtacaaata aaattgaaat atatggaaga
    94501 atatagaata aagatgagat ttgtctaata tttttataaa ttaaaaatat tttcaaagag
    94561 tttattataa aattgtagac tatagtgttt ataatctttg taattattgg taactaaatt
    94621 taaaaaataa aatatttaat tatacacaaa aaagatattt aaaaaatttg ttatttattg
    94681 tatacttaag ttaaaactaa ataggcaaat ctagagaaat ctagtgacgc aaagctatag
    94741 gggctaaggt ttgtatacac aaactatgtc agccagttgc caaaaagagt tctaggtata
    94801 ttgtatacgt aggaagagtc taggatgact gcctttttgg tggtcatttt gttatggaaa
    94861 aaatcacatt atgtagtaaa aaacacctat aataacatat tataccaaat ataatttaaa
    94921 ataaagataa attatctata aaagttacta ttttacaaaa aaaggcaact ttataaagaa
    94981 atatttaaat ttatattaaa atatttttat atttttatta ggatttacga aaataatatt
    95041 agttttctta ccaaagtgat acattattat attaatgtaa tagaaatgta attaatttgg
    95101 atgaataaag aagtcatttt ttgtaatata gcaacttcat tttttattaa taagcaaaat
    95161 aaataaaata tattttgagg aggagtgagt gtgaatacat atgacattat aaaaatggga
    95221 ttagatgcaa ctaatttaag aagtcagaca atagcaaata atatagccaa tataaatact
    95281 gaaggatata agagacatta tgtaactttt gaagaaacat taaatgatgc tatgccaaaa
    95341 atagaagaaa aaacagacaa ttctaaagga ttaagagtgg atggcaataa tgtagatata
    95401 gaagaagaaa aagtaaatca agcaatggca acattacaat ataatgcttt gataagtttt
    95461 gcaaatggaa aaatagcaat gactaaatca ataataagtg ggaggtaatt aaaaggtgag
    95521 tgtgttcagt ggaatgagaa tatctgctag tggattaaca gcagaaagct tgaaaatgga
    95581 tatcatatcg tccaatgtag ctaatataaa tgccacaaga ggtccaaatg gagaagcata
    95641 taggagaaaa gttgtttcat ttgaagaaaa ctatgataat aaattaggta tgctaggagt
    95701 aaaagttaca tctgttgaag atgataaatc acctcttaaa gaagtatatg acccatctca
    95761 tccagatgca aagccaaatg gatatgtaga atatccaaat gtaaatatat tggtagaaat
    95821 gacagattta ataacagctt cacgagcata tgattctaac gtagatacat tgaatgctca
    95881 gaagtctatg atatcaaaag ctttggaaat aggaaagtag ggataaatta tgccaattac
    95941 acaaattaac aatttaatgc aaggtgcaaa gttagataat ttgattggag aaacaaaacc
    96001 attaactctt aataataaag aagaaaaaaa gaactttgaa gatgtaataa tagatactat
    96061 agataaagtt aattttcaac aagtgacagc agatgatatg aaagaaaaat ttataaaagg
    96121 cgaagatgtt tctatgcatg aagttatgtt aataggtcaa gaagcacagc tatctatgca
    96181 atatttaata gaagttagaa ataagattca tgatgcatat caagaaatga ataaggtaca
    96241 aatttagcct tttgaacagg agtaataatc aatgatagcc agttttaaaa ataagattaa
    96301 agagcaagtt gctaaatcta ggacaaagat aagttctcta aaaaagggaa ctaaaatagc
    96361 attaggtata ggggttattg ctatatgttt agcgctagta tttacagcaa tatctgcgag
    96421 caaaaataag tatgcagtct tattttcaga actagatgtt caagatgctg cagatatatc
    96481 agcagaatta gagtctaaaa agatagatac taaggtaaag ggaagtacga tttatgtacc
    96541 tagaacagaa gttgataagt taaggctgga gctagcacca agtcttacag gtggttctaa
    96601 aggatttgca ctaatggatg atagttcatc aataggactt actgatgaag agtttcagat
    96661 taagaagcaa agaatgatac aaggtgaaat agaaaaaaca ataaagagtt ttccacaagt
    96721 ggaagatact agagtacata taacatttgg agagtcatca gtatttgaga aggaggctat
    96781 tccagggagt gcagcagttt atttgatgtt aaaaccaggg acgactttgg aaaaaaacca
    96841 aataaaatct gttatggcac ttatatcagg aagtgttaca aatataccag agaaaaatgt
    96901 tcaagtcatt gataacaaaa tgaatttatt atctgaaggt attttagagg atgaagatgt
    96961 tgatgaaaat aatcaaccaa caaatagttt gattaatgtt gataaaaata aggcatctga
    97021 acaagcattg aataaacaat tagaaaagtc tattttagaa atgctagaac caatatttgg
    97081 taaaggaaaa gtaaaagcca cagtaaatgc tgatttaagt tttgatacag ctgaaaaaac
    97141 tgagataaaa attgaccctg ataaagttgc aataaaggag acaaggtcga aaaattcatc
    97201 taaatctgct acaaataatg ttcaaggtgt agatgctaac atgaataacc aaggaaataa
    97261 caatggtact aatacagaag atagtttaga tgagagtttt gagtatgaaa caggtaagat
    97321 tgaaactcac actatagttg cgcctggaga acttaataga ttgacagctt ctgttgcaat
    97381 agatggaaaa atagctaaag gtgtacaagc tgatgtagag gatattgtta ataatgctat
    97441 aggtatggat ggagcgaggg gagatactct tagcgttgtt tcaatggtat ttgacccaga
    97501 agggaaggca gaagctaaac aagagctaga agagattaaa aaagaaggat ttaaaaagaa
    97561 cataataaaa gcagttattg gagtagtggc agtggtagca attggagcta ttggatactt
    97621 aatatataag aaaagaagtg aacgagaaga tatggattat gaagatgaag attatatttc
    97681 taaatctgat tctgttgata ggaaggataa tcctctatta ggagatgacc cagaactgac
    97741 attagaggaa gctgttaaaa tgtatgcaga agaaaagcca gaccaagtaa cagagataat
    97801 aaaaacttgg ttaaatgagt aagggggata gaaagtgtcc acggaaatta caaatgttaa
    97861 tgcgtttgac ttaagtgata taaatgaaag tgataagaaa gagaagatag aaggtgaggg
    97921 tttaaaaaaa gctgctgtat tattaatgac attaggacca aatgtgtcta gtgatataat
    97981 aaaaagcttg cctgataaac aagttcaaaa aataggttta gaaattgcaa atatttcttc
    98041 aatagcttca aaagaaagaa gagaaatctt aaaagagttt gtagagataa atagggcaaa
    98101 agattatgtt atagaaggtg ggcttgaata tgcaagagag ttgttaagca atgctttagg
    98161 aaatgctaaa gcaaacaaat tacttgaagg tatatcaata aatacaagta caaagccttt
    98221 taaacatatt ataaaactag atgtaaagaa aatattagaa atacttaggg atgaaagtgc
    98281 acaaactata gctgttttac ttgcacatat ggagccagaa aatggagcag aagttttatc
    98341 atacttagat tttgatttac aaaatgaagt agctatgaga ataagctcaa tgggttcaat
    98401 atctccagaa gtaataaagg taattgaaag ttcattagaa gataaattac actcaataag
    98461 tggtgatgat tttaaggatt atggaggagt gtctacctta gttcaaatat tgattaattc
    98521 tgatagaaaa acagaaaaga atattttggg aactattgaa gaacaagacc cggctttagc
    98581 agctcaaatt aaatctcata tatttgtctt tgaagatatt gtcaagttag atgatataag
    98641 tatacaaaaa gtattaaaag aagtgactat gaaagattta gtatatgcct taaagggtgt
    98701 ggatgatgag atttcagatg ctatatatag aaatcaatct tctagagcag cagatgcact
    98761 taaagaagaa atggaaatgg ttggtgtcat aaaagttaca caggttgagg ctgctcaaca
    98821 aaagatagca aatatagtaa gaaaacttga aagagaaggt gccataacta ttgtaaggaa
    98881 ttttggtggt gactttgttg aataataaga ttattaaaag taaaaaagca tcatataaag
    98941 gagtgctaga tttaaccata atagataaag ttagagtggg agaatcaaat gtaaataaag
    99001 aaaatgattg tagatttaga gatgaggtaa taaaagaagc tatagaatct gctgagataa
    99061 aaaagaatga gatattagaa gaagcaaaaa tgaatgcaca aaatatagaa aaacaagcat
    99121 atgaaaaagg gtatagtcaa ggtcaaaaaa atggatatga agatggatat aaagagtcat
    99181 atgatgaata tacccaaaaa gctaaagatg aagcagattt tataaaaaat caggcagact
    99241 taatactatt acaagctaat gagaagatga ctgagtacat aaaagaaaaa aataaagaga
    99301 ttgtaagact tgctattaat atggctagtt ctgttctaaa aaagcatttc gaagatgaag
    99361 aatctatgag tgatttgtta aagcaaatta ttcaagatta tgaaggaagt agttcattta
    99421 tagtaagatg taattctttc tataaagata atatagagaa agagtttgaa ttattcaaag
    99481 aggaaacatc actaaaatca agtgtatttg ttattgcaga tgatagtata gataaaggca
    99541 atgctatcat ccaaaaggaa aatggaagaa taatagttgg tatcgattgt gctatggaaa
    99601 aactaaaaga agaattgctt ggtgaataaa gtatgtataa aactgatata tctatagatt
    99661 ttgacaaaat aaataagaaa atagaaaatt tagaactcac tatatcagaa ggtagagtaa
    99721 agaagataat aggacttact gtagaagttg aaggaataaa agcttttgtt ggggagttat
    99781 gtgttatata caatcaagtc aataaaccag tgaattgtga agtagtgggt tttaaagata
    99841 aagaagtcat attaatggcg ttgggagagc taacattgat agctcctggt tgtaaagtta
    99901 tttctaaggg aataccttta agtgttatgt gtagcgataa tttactaggt aaagtacttg
    99961 atggtcttgg aaatcctata gacaactcag atgctgtttt aggagataga tacaacttga
   100021 acaatgaacc tcctgaccca atgaagagaa aaaagatacg aaatataatg gaaacaggtg
   100081 taagagcaat agatgcattt actacttgtg gtgaaggaca gagaataggg atatttgcag
   100141 gaagtggagt aggtaagagt acgactctag gtatgattgc taggaatgca aaagcagatg
   100201 taaatgtaat tgcccttatt ggagaaagag gaagagaggt actagatttt attgataaag
   100261 atttaggtga agagggaatg aaaaaatctg ttgttgtatg tgcaacatca gataaagctc
   100321 ctttggttag gctaaaaggt gctcttactg ctactgcaat agcagagtat tttagagacc
   100381 agggaaaaaa agtaatactt atgatggatt cagtaactag atttgctatg gcacaaagag
   100441 aagttggtat agcaatagga gaaccaccag ctcaaaaagg atatacacca tctgtatttg
   100501 ctattttacc aaaacttatg gagagaacag ggacatcaga taaaggttct ataactgcat
   100561 tttatacagt attagttgat ggagatgact ttaatgagcc aatagcagat acaacaagag
   100621 ggatacttga tggtcatata gttttatcta gagacttggc aaataagaat cattatcctt
   100681 ctatagatgt attgaacagt ttaagcagac ttatgaatga gattgcttca aaagaagaca
   100741 taaaaatagc atcttttgcg agagatatgc ttgctgagta tagagaagca gaagatttga
   100801 taaatatagg tgcatatgct tcaggtacaa acaaaaaaat agatgaagca atctactatc
   100861 atgagcatat tattaatttt ttaaaacaag gaataaatga aaagagttct tttaatgaaa
   100921 ctataagtag tttaagaaga atctttgaat aaacaattta aaaaaatatt tgaataggtt
   100981 gtgatggaat tggataaaaa ttttaagttt agattacaga aagttttaga cttaaaaata
   101041 aaagatgaag aagagataaa aatggaattt gctaagattc aacaaaaaaa aatagatata
   101101 gagagcaatt tagaaaactt agaaagtaat tacagcaaat attctataag taaaaataat
   101161 gatagtgttc aaaatcaaaa aataactatt aactatttgt tagctttaaa caactctata
   101221 atggatttat cagaagagct ggataagtcg acaaatgaac ttgaaaaagc tagaaagcag
   101281 cttataagca aacagataga gagaaagtca ttagaaaaat taaaagaaaa aaaatatgga
   101341 cagtattata aagaagaaca gttaaaagaa caaagcacta atgatgagtt tgcaagcatg
   101401 agttatttga gaaatagaca agttctataa aatagtagga agtgaggata ttattgtatg
   101461 aagatacaag cagattctta taatattatt aaagatattg ggaatagaaa aagctcatct
   101521 aagaataaaa atataaaaaa taataaattt gaagataatc tatataaggc aacagaccat
   101581 aaaaaggtta aagatagaag agaaacaagt aagcaaaatg ttagttcaga taaacgggaa
   101641 aatagtgata atgagtgtca tttagatgaa gataaaagta atcacttaga agatgaaaat
   101701 acatatgaaa aagattgtag taataataat gaagctttac atcaattact gaatctttta
   101761 aaagataatt acaaaaaaga taaagatata aacactatat tgaataatct aaaaaaacta
   101821 agtatatcag atgaattaaa acaagaactt aagcttaata aaaatatatt aaataagatt
   101881 gcaaatcaaa atttagagtt aaatagagct agtacaaata accctaatga tatagaaaat
   101941 ttagacataa tgaagttaag agaactttta gaaaataatg ctagtgaaga tattgaagta
   102001 attagtaaaa ctacagaaaa tgatactaaa agcatagact tgtacagttt tgacagcaat
   102061 agaatagata ctcttaactc aaataaacag aaagatgata gttctgatat tttggaaaaa
   102121 ctagcagggg taaatggaaa taagagtgga aattttggac aagtaataaa taaaagcgtt
   102181 gatatgaata aaattaaaaa tgataatgtt aatttaaaac agatagaatc aaatgtaatg
   102241 gatgattcta taaaagctat taagcatatg aaaacaaatg atatacaaga attgacaatt
   102301 aaattaagac caaaagaatt aggagatatg aacatacaat tgttaaaaga tggtgaaagt
   102361 atgagagctg ttgtgactgt tttcaacaaa gatgtctttg actctataaa taaaaacata
   102421 gcagatttaa agcaacatct tgaacttaca aatgtaaata taaaagatgt atcagtgcaa
   102481 atgcatagcg ataatacaaa tacatctgat acctttgata aagcatttga acaacagaat
   102541 agacaaaata accaagaaaa catgagtaag caaaatacaa atgataagcg taacaatgta
   102601 gtcatagaag atgagattaa agaaaatatt attgatgatg atagagtaga tttactagct
   102661 tagtaagggg gaagtattgc atgtacggaa tagcaacggc tttggcagga actcaggtaa
   102721 actataggtc aaataattta agccaacttg aaagaaatat taatgatatt gccaataaac
   102781 aagttagaag taaaggaaat cagacagtaa cagacaatgg gactccaatt ataggacaag
   102841 gcgatgatgc tgataaagat ttgtttatga agattcttgt agcacagatg ggtaatcaag
   102901 acccaatgaa tccacaagac ccaacagaat atgtatcaca attagcacag tttgcaactt
   102961 tagaaaagat gtcagctatg aatgataagc tagatatact tttagcctta agcaattcca
   103021 ctctaataaa ttctgctttg agtatggcaa catcattaat tggtaaagaa gtagaagtat
   103081 ctggggaaga ggaagaagat gaaaacattg taggagtagt aaaatccaca tatataaaag
   103141 atggggaagt acacttagaa ttagaagtag atggaagtga caaaactgta ggtgttaaat
   103201 atgaaaaatt acttaaaata ggagaggtag atgcaaattc aggagaagaa aatgactctt
   103261 cagaacaaga atctccagaa gaagtataat attaaatgag aaaagaggta aatttatgat
   103321 aaaagcaatg tattcaggtg taagtggaat gaaagcaaat caaacaaaac tagatgtaat
   103381 aggtaacaat gtagccaacg ctggaactac ttcttttaag aaaagttcag ctagaataac
   103441 agattcattt tatcaaactg tactatatgc aagtgctcca acagcggcat tagggggaac
   103501 aaacttagga caagtaggtg taggtagtaa gatatcaagt ataaataaag atatgacaca
   103561 aggaaatgta caaccaacta ataggccatc tgatttaatg atagatggag atggatatct
   103621 tccagtagta agacaaggaa cagttatgta tacgagagat ggttctttta atttagatac
   103681 aggatttaaa gcagctgatg gtgctttgaa gaatattaaa ggtggaagac ttgtaaatgg
   103741 tgatggatat atgttacaag gtgtgattta tgatggggaa tataaagctg atactggaga
   103801 attcattaaa aagggtgatg ctaaaggaaa agagcctatt gtaataccac ttcaaagtat
   103861 aagtcctaag gatggaacag ttcaaaatgt actagagtat aatatatcaa aggatggaac
   103921 agtagaattt ttattgagtg atggtcaaag aactcaattt gtctatgata tacctgatgg
   103981 tgctaaggta ggagatacac ctgctggaat agataaatta aaaggtacaa tacaaaaagt
   104041 gcaaacatat gcattccaaa atccagcagg actagatgca gaaggaggaa acttattcaa
   104101 gccatcagca aactcaggag atccacaaat agcaggagct acaggaaaca taatacaagg
   104161 ggcaatagaa gcttccaatg tagatatagc agaagaattt acagaaatga taatagcaag
   104221 taggtctttc caagcaaaca gtaaaataat atcgacatca gacgaaatac ttcaagaaat
   104281 aataaatctt aagagatagt aggtacatat tatgataaga gtaacggatt taaacggaag
   104341 aagatacata ttaaattcag accttatagt gagaattgac tctgtaccag aaagtaggat
   104401 tctccttaca acaggagaaa aaaatcttgt aaaagagtca gtagatgaga tagtagataa
   104461 agtaataaag tataaaagaa aagtaaatgt aggttatatt aggagtgaaa aataatgaaa
   104521 aaaacagatt cactaacatt cattggacta atattatcta cagtattagt tttatttggg
   104581 gcagtaaaag gaagtagttc aggattgaaa agttttttcg attttgcatc tatattaatc
   104641 acagtatttg ggtcatttgg agctttgatg attacattta ctattgatga tataaaactt
   104701 ataaaagatg cgctacaata ctcattcaag acaatgaata tatcgaaatt agacttatta
   104761 aatcaattta aaacactttc taaaaaagca agaagagaag gacttttatc tatagaaagt
   104821 gatgtaatga aaatacaaga cccatttatg aaaaaagggt tagagttatg tattgatggc
   104881 cttgaagtaa atgaaataag gtctatacta gaactcgaaa tagattctgt tgaagaaacc
   104941 aataacagat attctaaact atttaaaact tgggggactt tcgcacctgc atttggtatg
   105001 ttgggaactc taataggttt aatacaaatg ttatctgacc ttacatctcc agatttaata
   105061 gcatcgggta tgggaaaagc attaattacg acattttatg gttctttact tgctaatatc
   105121 gctttgaacc caattgcata taatatagat gagaagactg aaaaagagat ttatgtaaag
   105181 gaaatgatgc tggaaggtat aataagcata caatctgggg agagcagcat agtagttgag
   105241 gaacgtttag ctacatacct ttcaaacaat gagaagctag aaattatgaa atccaataaa
   105301 aatacagaaa gagcaatgag taatggcgcg taaaaaaaat aagaaaaagg atgagataaa
   105361 tccagatgca tggttggcta cttatgcaga tactataaca ctgattctta cattttttgt
   105421 gttattgtat gctacatcag ttgtagatat ggaaaaattt aaaaacatag cagatgcgtt
   105481 aaaaggtcag ttttctggga taagtatgtt cagtacaggt tcaagtacaa gtgagaagtc
   105541 tccaatagag agtgttttag tggataaaaa tgataagtca aatttagaac aggatttaaa
   105601 agataaagtt aataattcta acttacaaaa tagtgtaaca gtcaaagatg atagtagagg
   105661 gattttacta gaactagatg attcaatttt atttgactct gggatttctg aattaaaagc
   105721 agatagtaaa gccactctta ataaagtata tgacatgata aagatgatga aaaataagat
   105781 agttatagaa ggccatactg ataatgtacc tgtaaaatca agtacacatg aatccaattg
   105841 ggatttatct tctagtagag cagtaagtgt tgtaagatac tttgtagaag aaaagggcat
   105901 ggaccctaga ctattttcgg caacaggatg tggagagtat caacctttgg tttcaaatga
   105961 aacagcaaag ggaagggctg agaatagaag agttaatata cttataacta ttgactagga
   106021 ggaagaggtt tgttcaaaaa taaaaaaatt attataatta ttttgatact gattattttc
   106081 tcagcaggag caggtttttt tatattagga gaaggtggaa ataaacaaat tgacaagatt
   106141 gcaggtttgt ttattccaac agggaaaggc aaagatgaag taaagaccga aaatcttgac
   106201 ttagaagaga tggtattaaa gctagctgat gaaggtgtaa gatatttaaa agtatcaata
   106261 actgtatctt atgattcttc atataaagat atagaaaaaa atacgccttt aattagggat
   106321 aatattataa attgttttat ggcaaaaagg gcagatgatt ttactgctga taatttaaag
   106381 aacataaaag aagaaattaa aaatacatta aatatacaac taggtgaaaa tgtaattcaa
   106441 aatatatatt tcacaaatat agtagtgcaa taaaaggatg gtaagacatg atactttatt
   106501 tactaaaaat attaatatgt atcccaataa ttttaatatt gatagtctta tctttaaaaa
   106561 ttagccaagg aactttatta aaaaaatata atgataaata tataaaaata ctagatattg
   106621 taaatataag taaaaacaat agcataataa ttttaaaaat aggtgaagaa ggatgcatta
   106681 tggcatcttc ttcctctagc atgaataaaa taaaagattt gaccaaagaa gaaatattaa
   106741 gaatagaaaa cgacattaaa gaaagaaatt ttaaaattca agattttaaa atggaaagaa
   106801 ttaaaaagaa atatgatttc agtagatata ttggaaaatt tacaaaaaag gaagataagt
   106861 aaatggaact attatcaaaa ttacctttgg ctgatgtacc atatacaagt tcaatgcaat
   106921 tgtttttatt tctaactgca ttaatgtttt taccatttgt aatgtttatg atgacaagct
   106981 ttgtcagaat agttataagt ttatcatttt tgaaatcagc attaggagca cagcaagcaa
   107041 ttccaagcca aattttggta gggcttgcaa tagtattgac aatatttata atgagaccag
   107101 tattaaatga gataaacgaa aaggcattac aaccatatat gaaagaagaa gttactatgg
   107161 aagaagctat gaaggaagca gagggaccta ttaaagaatt tttattaaag caaaccagac
   107221 agacagattt agatttattt gtagaacagg ctggtttgaa agaaaagaaa ttaactcgtg
   107281 aaaatatacc actatctgtt gtagttccag catttgctat aagtgaacta aaaactgctt
   107341 ttcaaatagg ttttttaata tatataccat ttttgataat agaccttgtt gtggcaagtg
   107401 ttttgatgtc tatgggtatg tttatgttgc ctccagtcat gatatcatta ccgtttaagt
   107461 tattattatt tgtaatggtg gatggatgga acttgatagt aaaaacattg atattgggat
   107521 ttggatagga gaaaaatagt atgagtgaat ttatgataat gagtgttctt aaaaatggca
   107581 tgtttacagg agctatgatt gcagctccag tactcattgt ttctcttgta gttgggcttt
   107641 taataagtgt gtttcaagct acaactcaaa tccaagagca aactttgact tttgtaccaa
   107701 aactaatagc aattctttta gtagtagcta ttggtggaag ctggatgtta catactctta
   107761 ttagctttac ttcggagata ttcaatatga tgtctcttat aactaaataa gtaggatata
   107821 tatgattttt gtatttatta gaatagtggc attctttgga acactaagga tactatttcc
   107881 agctggtaca cctgctttat ttaagtcgct ctttgcaatc attatatcaa tattgatttc
   107941 aagtactatg caaattgaat atgcaacaaa tatagacaac attgtattgt ttaccttata
   108001 tggtataaat gagaccataa ctggcattat gcttggatat ataaccaatc tatgttttta
   108061 tagtatcaga atggcaggtt ctatgatgga tcaacagatg ggattatcaa tgattaatat
   108121 gtttgaccca aattcaatga ctcagacaac tttaattgat aatcttatga actggacagc
   108181 acgtatgata ttttttagca tggatggtca tcatgtttta attagaggca taaggtatag
   108241 ttttgagtta attccaatag ggaaatcatt cgtagataat aatatagatt atataataaa
   108301 catatttgtg cagtgctttt taactggatt caaaatagca atacctattg tactttgtct
   108361 gcttatggca gattttatat tagggcttat atcaagaagt gtacctcaac taaatgtaat
   108421 gataattggt atgccattaa aaatactggt tggtattgcg ttatttatca tatcaatacc
   108481 tttaattgtc aatcaaataa gtcatttatt aagtcaaata ccaaagatgt atgagggaac
   108541 tttcgcacta gctcctatgt tttttatggg ttcaacagat aaaacagaag aggctactcc
   108601 aaagaaaaag ggagaacaaa gaaaaaaagg taatatagca aagagtaaag aattacccgt
   108661 tgcaatgact ctacttgcat tcactttatt agtacctaca ttattttcat atgtagtgga
   108721 tacacttaaa tcttctctta attatttttt gagtctagat ttttatatga atataaatta
   108781 ttcaagtata gagaaattag ttatagcagg attaatggat ttttttaaga tatttttacc
   108841 aatagctatt ccattcttag ttttaggtat agtcgcaaac ctatttcaag tgggaatact
   108901 gtttactggt gaaactttaa aacccaattt atcaaaatta aatccagtta gtggatttaa
   108961 aaacatgttt tctatgagaa gtttgtcaac cttaataaag gatacagcga ttatatctat
   109021 tttggcttac ataggatata cattcttcca agataattat ttagatatat taaagctagg
   109081 taacatatac ctgccaactt taatgtacac agttaaagat ttagtatatt caatattaag
   109141 taagatttgt gtagctatga tagttatagc agttgcagat tatgtttatc aaagatacag
   109201 tcataaaaag caacttagaa tgacaaaaca agaagttaaa gatgaatata aaaactcaga
   109261 aggagaccca gaaataaaag ctaagataaa acaaaaacaa agacaaattt cgtctcaaag
   109321 aaccatgcaa gcagtaccaa gtgctactgt aatagtaacc aatcccaccc acttatctat
   109381 agcagtgaga tatgaaaaag ggaaagacca agctccagta gtggtggcaa aaggtgcaga
   109441 ttatttagct tttaaaataa gggaaattgc aaagggaaat gacataccta taatagaaaa
   109501 taaacctatt gctaggttgt tatataagca agtagaaata gaccaagaaa ttccagagga
   109561 catgtatcaa gcttttgcag agatattagt agcagtatat aaaatcaaaa atagatacaa
   109621 agtcctcaaa aggtaggata agtaatgaat aagtttaatt taaaggaaaa tatggacgta
   109681 atagtggcat ttggtgttgt agggattgtt cttatgatga tagtgccgtt acctacattt
   109741 atattagata ttttactggc aattaacata agtttatctg tgctaatttt actaatgaca
   109801 ttatttacaa caaatgtact tgatttatct atatttccaa cagtgttact tgtgacaaca
   109861 ctatttagat tgggattaaa tctttcatca actagattga ttttaacaca gggatatgca
   109921 ggtgaagtta tagaggcatt tggaagtttt gttgtaggtg gaaattacgt agtaggaata
   109981 attatattct taattatatt aattgttcaa tttgttgtta taaccaatgg ttctggaaga
   110041 gtatctgaag taacagctag atttacgtta gatgccatgc caggtaagca gatgagtata
   110101 gatgcagatt taaatgcagg agttatagat gacaaaactg ctagaaaaag aagaaaagag
   110161 cttcaacaag aagcagattt ttatggctct atggatggag caaataagtt tgtaaaggga
   110221 gatgccatag caggtcttat agtaacagca ataaacataa taggtggaat tgtaatagga
   110281 gctgtaatgc tgaatatgac tcttatgggt gcagcacaga catatgtaag acttactata
   110341 ggggatggtc ttgtaagcca gatacctgct ctattaatat ctacatcagc gggtataatc
   110401 gtaacaagag cttctactga tgaaaacttt ggtggattag taagtaaaca gttaacggca
   110461 ataccaaaag cagtaatgat gactggttgt gttctaatcg tacttggtat gatgcctgga
   110521 ttacctaaac cagcattttt ttcactaggt ataggtgcta tagcagcagg ttacttttta
   110581 ggaagagaaa agaaagatac tttagaagac ttggagtttg aaaaacctga tatggtaaat
   110641 ccagataaaa atgaagtaga agatgtaaca aacttaataa atgtagaatc aatagaagta
   110701 gaaattggat atggtttaat atctttagct gatgaatcag caggaggaga tttacttcag
   110761 agaatagcat caataagaag acaatgtgca atagacatgg gtatagtcgt gcaacccata
   110821 agaataagag ataatttaca gttaaatcca aaccaataca atataaaaat aaagggaaat
   110881 gtagttggtg ggtatgagat aatgcctaat atggttttat gtatggaccc tatgaatcaa
   110941 ggatttagta tatttggaat aaagacaatt gagcctactt ttggaataga ggcactttgg
   111001 atagaaagtg acaaggtaga agatgcagag ataaagggtt atacagttgt agattcatcc
   111061 acaatactta taactcactt actagatata ataaaatcaa atgcacacga attactggga
   111121 agacaagaag ttaagactat tatagatgca gcaagagaaa attatagtgc tgtagtagat
   111181 gaattgatac cagatttaat gacacttggt gaaattcaaa aagtacttaa aaatctgtta
   111241 agagaaaaag taaatataaa ggatagggtt acaatacttg aaacgcttgc agaccagtct
   111301 agaaatacaa aagatataga gcttcttact gaatatgtaa gaatagcctt ggctagaagt
   111361 atttgtaata atttagttga tgatgataag acaattgtag tggctacatt gtctccagaa
   111421 actgaagagt tggtatctaa taatttacaa aggtctgtaa atggaactta tccagcagtt
   111481 gacccagaaa atacaaataa aatatttgag agtatacaag aagtaatgaa caatgtatat
   111541 ttcaatcata atataccagt aatagtagta tcaccaaaga taagagctcc atttagaaaa
   111601 ttagttgaaa ttgtatatcc taatttgact gtattatcat taaatgaaat acctaacgat
   111661 attaaaatca aagcagaagg tgtggtgagc atatatgatg acgaaaaagt atacagctaa
   111721 cacaattcag gatgctatga atctagccaa aatggaattg ggtgacaata ttacattaat
   111781 agataaaaaa gaagtaagaa agtctggaat acaaggtatc ttttcaaaga aagatattga
   111841 actaactatt ggatgggaaa agagagaaaa cgtagaacaa aaagatttaa aacgagagat
   111901 agaacaatta aagttaatta ttaacaatat ggggtttgat aataagaatg ataatgatat
   111961 agataaaata tgtaaaaatc tactaagttt agaattaaat gaagaaattg tagaatctat
   112021 aagaattgat ttgcaagaaa tgaagttcaa tggaattgat acaagcaaaa atttagtaga
   112081 aattttaaag aaaaagatta aaatagaaaa tcaagcaata aatggtaaaa ttgctctagt
   112141 cggaccacca ggagtaggta aaacgactac aatagcaaag ttagccgcaa aattagtttt
   112201 tgaagaaaat aaaaaagtag gagtaataac tatagataca tacaggattg gtgctgtaga
   112261 acagttgaag atatatactg atataatgaa tattcctttt aaaggggtaa taagtcccga
   112321 tgaaatggaa ttggcacttg atgagatgaa agattgtgat gttgtattaa tagatacaac
   112381 aggtagaggc tataaaaact ctatgcaaat actagaaatc aaaaatctta tagataaagc
   112441 tgaaactgat aatatacatt tagttgtgaa ttgtacaaca agagaaagtg atacaaaagc
   112501 aattatagat tcatatagaa atgtgaattt taaaagctta ataattacaa agctagatga
   112561 aacaataaca tatggctcaa tatttaacat aatgaattat gcacaaaaac caatatcata
   112621 tattacaaca ggacaaaatg ttcctgatga tattataaaa cctaatgaag ataagattat
   112681 aaggttacta ttaggagttg aaagtatatg atagaccaag ctcaaatttt gagaaaaatg
   112741 gcaatggaaa aaagaggact tgatgagttt atagtagaga atgagaatgt acctaagata
   112801 attacaatag cttctggtaa aggcggtgtt ggaaagagta atctcgctac aaatttgtct
   112861 atatgcttga ccaaacttaa taaaaaagtt cttatattag atgcagacat aggaatgtct
   112921 aatatagata taataatggg ggtaaatgta aaagggacta taattgatgt aattaatggc
   112981 gaaaaaaata tagaagatat aatttcacag actaagtatg gtgtaaatat aatatctgga
   113041 ggttctgccc ttaatcatat agaagacttt acagaagctc aaagaaataa gtttatacat
   113101 agcatagaac agattcacga tgtggatttt ataataattg atacaggagc tggtatgagc
   113161 aaaagcctat tgtcatttat atactgtagt actgaatttt tcttaataac aactccagaa
   113221 ccgacatcat tgactgacgc atatagttta ttaaaagcta taagtaattt tggcataaag
   113281 agaagtgcaa atataataat caatagggta attgatttag aagaagcaaa atctacatac
   113341 aaaagaataa aaatggttgt ggacaaattt ctaaacctta atctagaatt gtatggatat
   113401 ataatagatg acaaaaaagt aagtttatgt gtaaaaaaac agataccatt cattttagaa
   113461 tatcctacaa gtattgcatc aaaatgtatt atagccatag caaagagaat ggtaagtcag
   113521 tcaagagaag atattgttga taataaaagt tttctaagaa agatgtttag tatatttaaa
   113581 agctaaggag gcgtagttaa tgaatagaga agaattaata aaagagaata tgcctcttgt
   113641 aaagagtata gcaagaaaat tttttatacc agggaaaggt tttgaatatc aagacttagt
   113701 aaatagtgga gtcattggat tgattgatgc aataaataaa tttgatgctg aaaagggggc
   113761 aaagttttct agttactctt atataaaaat aaaatctgct atattagatg aaattagaaa
   113821 tcaaagtcca atttctaaac ataatctaac taaagtaaat aagtataata gagtggtaga
   113881 aaagttgcaa tctaaattat taagagagcc aacttcatat gaaattgcaa aagaattaaa
   113941 tgtttcagaa aaagaacttc atgatatcga aagtaatata gacatgttaa atattgtatc
   114001 attaaactat gtaatctttg aagatacaaa tgaaactgta caagatgtaa taagtgatag
   114061 agaagaggaa gctccagaaa atataataga agaagaagaa aagttagaga ttctatctaa
   114121 agcaattagt aatttaaatg aaagagaaaa attaatactt tcactgtact attatgaaga
   114181 tttaaatcta aaggagatag ggaaagtgct aggtgtttca gaatcaagag tttcacaact
   114241 ccacagaaaa tcaataagaa acttaagaaa caagataaaa gaacttaaat attctatata
   114301 gatggtgatt gataagatga tacaaattat attaatagta gtgtctattt taataatagt
   114361 aactatagtt ataaatttac ataaggaatc aaaaaataaa gataacagat actttgataa
   114421 aatatttgag caagaatatg aagcaaatga tagattaata attgcagaaa aaagaagatt
   114481 ctttttagac aaagtacttg ctgaaataag aagtaataat catataaaag tttatgaaaa
   114541 ttataaccta ataaaggcta atgaagaaag aaaggaaaac atatttatag aatcaaaaaa
   114601 ggaagtaaga caagaaaatg agttatctct taaagtgaaa catcttataa gttcaggtta
   114661 tgatgatgtg gaaatatgta agatgctaga tattggaaag ggggaactgt cattaataag
   114721 gagttgttac aaaatataag gatattatta tgtgataaaa aagtattctt aggaataggt
   114781 attggtatat taatatcaac tttatgcata atgcttttta gtaataatga tatgagtaag
   114841 gcagagatag aaaaaaaggc cagagcgtta ggcatgaaat atacaagtga gatgaaagtt
   114901 ttagaataga tgatactgtt tagacattta caaaaaagga ggtcataatg tgataagagg
   114961 attatataca gcagtttctg ctatgataac taatcaacaa aagcaaaatg ttgttgtcaa
   115021 taacctagct aatatggata caaatggata taaaagtaaa caacttttga ctaaaagttt
   115081 tgatgaatta aagttggagg gttacaataa ctacgcaaat ggaactaaac aaaagcagat
   115141 tataggcgat ataagtccag gtatttctat ggatgaaact atcacaaatt ttaatcaagg
   115201 acctataaaa actactgata ataaaatgga tgtagctatt caaggtaagg gattttttct
   115261 agttagtgat gcagctggaa atcaatttta cactagaaat gggaacttca gaacagacaa
   115321 tcaaggtgac cttataacaa gtgaagggta ttatgtactt gggacgaata ctgctactgg
   115381 tgctgtaggt catataaatg taggaaatca aaaatttgaa gtggcaaaag ataatacaat
   115441 atcactagat ggaaatgcta tgtataaatt caatattgta gattttaatg actacaataa
   115501 cttaaaaaaa gaaggagata acttgtattc tggaggagga gctatgaaag taaataatgc
   115561 acttacaata caaagtgcga tagagtcttc taatgtagat atggtatctg aaattaataa
   115621 tatgatgacc atatcaagag aatatgaggc aaatcaaaag ataattcagg ctatggattc
   115681 taaattagca aaaatagcaa gtgagattgg ttcagtaaga taggtgatag gaggtgaatt
   115741 tttatgtaca caatgtttta tactagtaaa acagctttat cagcaaatca aagtaaacta
   115801 gatataatat ctaacaatat agcaaattct gattcaacag gatataaaaa aataaatatg
   115861 gaatattctg atttagtgga tgaagtacta aatagaccat catatcctac aaatggcaat
   115921 gatatatcga ctggaacagg agctaaggca acagctccca tgagaattta tgaacaaggt
   115981 gcattggccc ctacagatag taagagtaat ttggcgatag atggagaagg attctttaga
   116041 gtgataagaa aagatggtac atatgcatat acaagaaatg gtggatttaa tatagatggt
   116101 ttaggtaaga ttgtagatga taatggaaat atattagatg ttcaatttga tgcaggatat
   116161 aactataata atacgaatat agatagcaca aacttaacag tttcaagaaa tggcgagtta
   116221 ttcgtagata ataaaaaaat aggaaaaatc aatttatatc aacctatagg aactcaaaat
   116281 tttatatctg aaggagatag tttattcgtc gcaactgatg cagcacagat taaacaagtt
   116341 gagaaagtag atatagttca aggctataga gagaggtcaa atgtttcttt acaagaagaa
   116401 tttgttgact taatagccac tcaaagagca tttcaaatga actcaaaggg aataaagaca
   116461 gcagatgaaa tgtggcaaat agctaataat ttaagagcta aataattatg taaggtgagg
   116521 aatattcatg aatgatatga aagagtacga ttttggcaaa cctcagagtt attcaagaga
   116581 aaatttaact tgtttaaatt ttttattagc tgaattttgt aaaaaatata aaaactatat
   116641 aatttatgaa cttaagtgta attctagtat gattgttgat agtatagacc aagtaaatta
   116701 tcagactttt ttagatagag taacttcttc atgtgtagta gtacaaaatg caatggaacc
   116761 tgttatgaaa aacttttctt ttagaataga tagaagtgta gctgatatgt ggattgatat
   116821 aacttctgga ggaactggag ttataaagga taatgataga gagcttacag aacttgataa
   116881 aaaagtgctt ttacatctta tggatgattt agtaagaaat atgcacttat ttgaaggttt
   116941 tgaaaatata caagtattgg atacacatac acatattaat ttaccacaat tatgttctcc
   117001 aactgcacca gtatgcgttg tagatttaaa agtgctaaat gataatgagt atattggaag
   117061 tgtttctctt tgttttccgt ataatggttt agaggctcta ttagaaagta tatctgttat
   117121 agaatttttt gataatgatg taggagatga ttcagaggaa tttaccaaaa aaatctataa
   117181 tagtgtatct aatatagaat tatcagttat tgcagagata ggaaaagtat caattaatgt
   117241 tgaagactta cttaaactag aagttggaga tgtaatagta acaaataaaa aaataaatga
   117301 ttatatagat atatttgtag aaaattcaaa atcatataca gcaacaccag gatttatatc
   117361 aagcaaaaaa ggtgtaaaaa taaatgatgc tgttggaaaa gaggtgtagt tatggacaat
   117421 agtaatctta tttcagatga agaagcaaag atgttattaa atgataaagt tgaaagtgaa
   117481 gttgatgggg atgatgagtt agccttagat gtctctgaag ttaatcgaaa taatatacaa
   117541 aggatacttg accttaagtt agaattatct gtagttatag ggagaactaa gatgactcta
   117601 agagatattt taaatttaca taaaggttct cttattgaac tgaatacttt agcagaccaa
   117661 gatgtggaaa tactaataga taataaggtt ttggcttatg gaaaagtagt ggtggtagat
   117721 ttaaattttg gtgtaaagat aacaagtata gtaagtgaag aagacatggt aaaatctctt
   117781 gtttagagat aacatcaatt aatacttaag gcatgaggtg gtacttattt taaacttaaa
   117841 tgatataaaa aaagatatac taaaactcaa taaaaaagac tcatgttctc tatataatga
   117901 atctattaat aatataaata ataattgtat atcaactgga ttaaaatttt taaaacaagc
   117961 aagagattta aacccagatg atgttgatat attaaatctc acaggtcttg taaacttact
   118021 aaaatgtaat tttgatgatg ctgtagaaag tttctataag agttcacttt gtgaaaaaac
   118081 tgctctgtgt gaaaagtata taaacatgct tacatctgag gagtttttaa ttttctttga
   118141 aaagtacaat caacttataa ggttaataaa taaaggaatg tataaagaag ctatacaagg
   118201 gtttaaactt ataactgacc aatactgtga tttaatagaa ccttatgagt tgcttgcctt
   118261 actgtatgac aaggaagaag aatatataaa atttgatgaa tgtttagaag tattgaagat
   118321 tattgataag gaaaattatt tattaaatca agaaaataac acattagata tgtataatag
   118381 tgctaatata caaactaaaa gtaatgtaaa agtagatgat tataagaatg agtttttaca
   118441 taaaagtagt agtaaccata aaattaatga ttataataat gtaactaaag aaaaaagttc
   118501 aagcaaaaac cagaaaagtt cagattctaa taagaaaaaa agtattaaaa aaaataagta
   118561 cctatatata gccataatat taggaatatt attagtagga caaagtatat atagttctta
   118621 taagatgaat aatttaactg ataaaatatc taaaaataat gaaactaaaa atgaagagtc
   118681 aatagattct aacttgacta agaaagaaaa taatatagaa gaaaatgaag atatgagtaa
   118741 ggcttctaat ataaataaga gtaataaaaa cattaataaa gaggctgatg taaaatctaa
   118801 aaaaaatact gtagaaaatg aagatgataa agattctgac ttatttacag aggatgaatt
   118861 gatgtctaag gcgaatactt taaaatcaga aaaaaaaact aaatcttcta tacaactata
   118921 taagaaagtt gcagatatag gtgaaaataa agggaataca tctgaagcaa cttatcaagt
   118981 tgctattctc agtgaaaagt taaaagacta taaaactgct gaagaatatt ataaaatgta
   119041 tgtagaaaat tactcagaaa aagatgctta ttttgatgaa tcttattata atttagggat
   119101 gatgtactat aacaatggtg atttaaaaaa ttctaaattg acattaaaga agttagttaa
   119161 taaggtacca aatagtatgt ataataattc aaaagtaaaa gaaattttaa aagaagaata
   119221 gttaaattag ataagaaaaa taaattattt tattttaaaa taatatgatt ataatatatt
   119281 gacataccat tttaaaaaat ttaaaatatt aattataaaa tgaggaggga taaaaaatgg
   119341 aatttgaaaa agggagtatt tcaattcata cagaaaatat ttttcctata attaaaaaat
   119401 ggttatactc tgataaagac atatttataa gagagcttat aagtaatgga tgtgatgcag
   119461 taagcaaaca caaaagactt gtatcactag gagaaatatc agaaaataag tcatcagatt
   119521 ataaaattac agtatctgta aataaaggag aaggtacact taaatttatt gacaatggaa
   119581 ttggtatgac tgaagaagag ataaaaaaat acataaatca agttgctttt tcaggtgctg
   119641 aagatttctt taataaatat aaggataaga tggaagagtc aaatgacata ataggtcatt
   119701 ttggattagg attttattct gcatttatgg tgtctaaaaa ggtacaaata gatacacttt
   119761 catatacaga aggagcgact cctgtaagat ggatatctga aggtggtaca gaatacgaaa
   119821 tatctgaatc agatgctaga aatgatagag gaactactat aacactattt attgatgatg
   119881 atagtaaaga atttttagat gaatttactg taagaggaat aataaataaa tactgttctt
   119941 tcttaccagt agaaatatat ttagaagatg ttgaaagatt agaaagagaa gctaaagaag
   120001 cagaagaaaa agctaaaaaa caaaaggaag atggaaaaga agagattgta gatgcaaaag
   120061 taattgagcc tttaaacgac actaatcctc tatggttaaa atctccaaaa gactgtactg
   120121 atgaggagta taaagagttt tatagaaagg tattcaatgt atttgatgaa cctttatttt
   120181 ggatacattt aaatgtagat tatcctttca atttaaaggg tatactttac ttccctaaat
   120241 taaaaaatga gtttgaactg actgaaggaa aagtaaaatt atacaacaat caagtgtttg
   120301 tggctgacaa tataaaagaa gttataccag aatttttact tttattaaaa ggtgttatag
   120361 actgcccaga cttaccatta aatgtatcaa gaagtttctt acaaaatgac agggatgtaa
   120421 gcaaaatttc taaacatata attaaaaaag tagctgataa gttaaaatct ctttgtaaaa
   120481 atgaaagaga agaatacaat aagttttggg atgatataca aatatttatt aaatatggtt
   120541 gcttaaaaga tgaaagtttc tatgagaagg taaaagaatg tatattattc aaaactattg
   120601 atgatgagta tataacaata caagattatt tagaaaaatg taaggacaaa catgaaaata
   120661 aggtatttta tgtaagtgat aaggaacagc aatctcaata cattaaacta tttaaagaat
   120721 acgacttaag tgctgttgtt ttaaactcat caatagatac tcattttatt tcatttatgg
   120781 aatataaaga gaatggagtt aagtttaata gaatagatgc agacctttct gatgtattaa
   120841 aagataaaaa tgaaaataaa gatagtgaag aaaacaaaga agagatagct aagatagaag
   120901 gtttgtttaa agaagctgtt ggagaaagag tgaagaatta ttctgtagaa ggattgaaaa
   120961 atgaagacac tccagctatg gtattagtat cagaacaatc tattagaatg gcagaaatgc
   121021 agtcaagatt tgctggaatg gatttaggaa tgaattttga ggaagaaaaa actcttgtaa
   121081 taaatgagaa cagtccaata atcaaaaaat tggtttctct taaagatgat gaggaaaaga
   121141 aagataagat tacgcttatt tgtaaccaga tagcagattt agctttactt tctaataaag
   121201 aattaaagcc agatgagtta gattcatttg tacaaagaag taataagctt atgagtcttt
   121261 tgatagaatt ataagattga atttgaatac attgaagcaa atttataaaa agtattcaat
   121321 atcagtgatg agaaagaagt gtctcaaaat gaacttttca gttcatgagg cgcttttttt
   121381 atgtgaaatt aaatttattt taatcatttc aacaatgaaa aatatattta tctctatttt
   121441 gagacagacc gttctttatt tttttatctt tggttaattt ttaaatattt aagtaggttc
   121501 taataaaaaa ctctatttag ttaaatatag ttaacttgat atataataag ataatacata
   121561 taattaagta aaagattgtt ttttagttta tgtttaaata cataattaca ctttgttaaa
   121621 aacataaaat tattactaaa gtagaaatag gaggttttag catgaatttt aattataatt
   121681 tgccagtaaa tatcttattt gggagaggca gaattaatga tgtgggaaaa gaagtatcta
   121741 aatatggcaa aaaagtattg atagtaacag gtaaaaatag tacaaagaaa actggattac
   121801 ttgataaaac aatagattta ctaaaagact ctaaaataga atatgaagtt tttgatagag
   121861 tagaacaaaa tcctcttata actactatat attcaggcgt agaaattata aaatcaactg
   121921 gatgtgattg tgttttaggg cttggtggtg gaagcattat ggatgctgcc aagagtatag
   121981 ctttttctta taaaaaccca ggagatttaa atgattatat atttggaatt agacaaggtg
   122041 aagaagcttt acctataatc ttagttccaa caacatcagg tacaggtagt gaaggaaatt
   122101 gttttgcagt acttacaaat tcagaaacta aagataaaaa atctataaag aagaatagta
   122161 tgtatgcaaa agcatcaata attgacccag aacttatggt tacaatgcca aagcatataa
   122221 ttgcatcagt tggatttgat gcacttgccc ataatatgga agcatatctt tctaatggaa
   122281 gaaaccctct tgcagatgta caagctattt atgggattga acttatatca gaaaacctaa
   122341 taaaggtata taatgatgtt aatgatttag aagcatggga aaaaataaca cttgcaagta
   122401 ctattggagg aatgacgatt ggtacagcgg gtacagcctt gccacatgga atggagcatc
   122461 ctgtaagtgg tcttagagat gtaatgcatg gaaaaggact tgcagcgttg actcctacta
   122521 ttatagaaag ttcatgggat attgatattg aaagatttgg taatatttca aaggtattag
   122581 gaggaacttg tgcagaagat tgttcagatg caattagaaa tttccttaaa aaaatagatt
   122641 tagatataaa actaagtgat ttaggtattg aaaaatcaga tatagattgg ttaactgata
   122701 attgtatgaa aatatcagtt gcaaatatta agagacatcc aaagtatttt aataaggaac
   122761 aaataaagga aatgtaccat aagtctttat aatttgactt tacatattta gttttatata
   122821 aaaattataa attaataata aaaaattata agtaattaat agtaaaaaaa ttgtgtatag
   122881 aagttatata tataataaac ttgtcttaag cttttatttt actttctaat aaataaagga
   122941 gtttaaaaaa gggaagatta attaagtaat attttataaa attcttcgat ttaaaaactt
   123001 taagtagagg tgaaataaat gtttaatccc aaaagaataa tattcgaaaa aggaacttta
   123061 gacactgatg tgggcaaaaa aatatacaat aaatttagag ataataaaga tgtagagata
   123121 attaatatat catcaaatag gattaaagaa cacattccag gtgaaaatct atatgaacaa
   123181 tatagaagtg ggaagcagac tatggtagtt gggattagaa aaagtctgaa gtttcaaaca
   123241 tgtaaacctt ctgctaatta tcaactacca cttgtcagtg gatgtatggg aagatgtgag
   123301 tattgttatt tgaacacaca attaggtgat aaaccattta taagggtgtt tgtaaatgta
   123361 gatgaaatac ttgaacagac aaaaaaatat attgaagata gaaagccaca ggtaaccata
   123421 tttgaagggg cagctacatc agacccagtt ccagtagagc catatactaa ttctttgaag
   123481 aaaacaatag agttttttgg aagagaggaa aaaggaagat ttagatttgt tactaaatac
   123541 agtgatgtgg atagcttatt ggatgctgaa cataataatc atacagaaat acgatttagt
   123601 atcaatactc ctagaattat aaatgaacat gagcattata cagcctctgc aaataaaaga
   123661 atagagtcag ctgtaaaact tgctagggct ggttatcaga ttggtttcat aatagcacct
   123721 gtgtttttat atgaaggttg gaaagaagag tataaaaatc tgattataag tataaaagaa
   123781 gctttaccaa aggattttga taaaaaaatt atatttgaag ttatatctca tagatataca
   123841 actaaagcaa aaaatagaat actagagatt tatccagata cactattgcc aatggaaaat
   123901 gaggatagaa agtttaaata cggtcaattt ggatatggta agtacgtgta tgataaagaa
   123961 caattagatg atatgaaaga gttctttctt aaggaaataa atggagtatt taaaaatagt
   124021 ttaataaaat atataatata gcaaatctta cctaaagatt tgctatattt tatttttata
   124081 tattttatgt ttataataaa gcaatgagat ttagcactat catataagaa aattaaaaag
   124141 ggcactatct atcaagaaca ttttttctag ttttgatact ataaagggta agagtaacaa
   124201 aaatatcagg aggagttata gtatgcatgc atgggagtct attcaaatta cattggattt
   124261 aatagaagca aatttatcag aagaaatatc aattaatgaa ttagcaaata aagcaaattt
   124321 atcaccattt tactatcaaa gactatttaa aagattggta aataagactg taatggagta
   124381 tataaagctt cgtcgtcttg caagagcttc tgaatactta gcagaacata agaatcgtat
   124441 acttgatgta gctttaaatt ttggatttgc tagtcatgag acatttacac gttcctttaa
   124501 aaaagcatat ggattaactc cagaaaaata tagagcaaat ccagtaaaac tcaatcactt
   124561 tattaagcca gaattaattt taaattatgc tatggttgat gaaggtgttc cactgattgc
   124621 agatgatata gtgattgaag tcaatcgtaa gacattgagt aatccaagga catttgttgg
   124681 aatagaaata gaagtaccta tttgccagtt ggtgggtggt gaaacaactg gaattgcaat
   124741 agtagaggaa ttatggatga aacttggaag tcaaagacat aatataccaa atcaaattcc
   124801 aggtggaaat gaatttgctg ctctttatat gggaaatgca aaagaaggaa attgtatgta
   124861 tatggcaggt gtagaggtag agtcaggtac atcagtagaa ggatataata cttttgagtt
   124921 gccagctaaa gaatatttag tatgtggatt tgaggcagaa aactttaatg agttagttaa
   124981 ttcagctgtt tttaaagcag ataaatttat ggaaagatgg atgaagaaac ataatttaac
   125041 aactactgat tttgcaattg agatgtatta ccccactaca cctgaagcag catatctgga
   125101 acattggatt gttccggttc ctattgaaca atagaaagga tgatgaatat gaattggcaa
   125161 gatgcgtttt ttcaagatac taaacctaca tttgagcaaa ttaatgaatt tattaataat
   125221 ccattatggg acaagttaaa taaaactttg gtttctactt ataatgtaga acctaagctt
   125281 gaatacagta aatgttcaat gcaaagaggt tggaatgtaa aatataaaaa aagaggtaaa
   125341 tcactatgta ctttatatcc acaagaaggt tattttaaag ctttggttat tgtaagtgaa
   125401 agcaatagag tagaggttga tttatttatt aatacttgtt gtgattatat caaaaaaata
   125461 tataatgagg taaacttttt taatggaagt aaatggctaa tgattcaagt agatagttta
   125521 ttggtattaa acgatatgct tgaactaatt aaatttagag cttaacatat agaacaggat
   125581 gaatatataa gtcatcctgt ttttatattc aatcagataa attaatatat agtctataat
   125641 atgaataatt tagtaaattt actttatctt tctacattct ttgcaactaa gtccacatgt
   125701 gtttttttct tgcatattag tagcacccca attagcaaat tgttgtaaaa taggcacaat
   125761 acttttacct ttacttgtta atgtatactc aacttttgga ggaatttcat tatattgttt
   125821 acgatgaaca ataccagtag actctaaatc ttttaatgat tgagctagca tagtatttgt
   125881 aatgccatcc aattttcttt ttatgctact atatctaatt ggattttcaa ctgctaacat
   125941 acatataata ggtaatttcc acttaccacc gacaatgtct aatgcataac ggattggaca
   126001 ggttaattct tcaacgtttt tagttatatt tttttcagta tttatactca ttttaattac
   126061 tccttagtta tagtagtatc ttttttatac tttatcagaa aaaactgcat acttgttttt
   126121 tctgtatttt atattaaaat tatatcaaag gataatcctt aatacaagta tttaaaaggg
   126181 gtgtaagaat tatgaaagca ttagaatttt tgaacaaggc aggagtttat tatttagcaa
   126241 cagttgatga gaacaatcaa gcacatgtgc gtcctttagg atttgttatg gaatacaatg
   126301 gtaaacttac attttgcaca tctaatcaaa aggatatgtt taagcaactt atttttaatc
   126361 caaaggttga actttgttgt atagaccaaa accttaatac tctacgtatt ttaggtgaag
   126421 cagtatttgt tacatcaaaa gaaacacaag ctaaggcact tgaaataatg ccaagtttag
   126481 gtcagatgta ctctgtggga gatggtaagt ttgaaatatt ctctattgat aaggcaaaag
   126541 ttagttgttg ttcaatgagt ggtaaaaaga ttgatgtaga gctttaatta taattgaatc
   126601 gacatccata gtgaaaatta agaaaacgtt attactgaaa tattgataga tttaatttaa
   126661 gtgcaataaa aagattttta aataatgaat atgtaaaaat ttttagttat tagatgtgta
   126721 tttcaataat gatatactat tttgaataat tacatactag aaataagata a
//
LOCUS       DAMJYN010000003        96636 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.003, whole genome shotgun sequence.
ACCESSION   DAMJYN010000003 DAMJYN010000000
VERSION     DAMJYN010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 96636)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 96636)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..96636
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.003"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            110..301
                     /locus_tag="PC466_000239"
     CDS             110..301
                     /locus_tag="PC466_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HDF2767675.1"
                     /translation="MKKVALILAIIGALNWGAIGILGTDLIGSIFGGTYEMVSRIIYF
                     IVGLAGLYLIPSLMSDDRE"
     gene            456..1865
                     /locus_tag="PC466_000240"
     CDS             456..1865
                     /locus_tag="PC466_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HDF2767676.1"
                     /translation="MFIINELNKIVNEEVISFHMPGHKKGQVYKKLGYKDILKNLYKM
                     DTTEILGTDNLHFPEGIIKNSQKKASRVFKSDYTCYLVNGSSCGIQSAIMSVCSPKSK
                     IITNRDCHQSVINGCILGDIDIEYVPCEISEETNVLKGISISNVIDIIDKNLDAKAVL
                     LTYPTYYGMTYDLEYICNYAHSKKMVVIVDEAHGAHLGLSERLPKTALEQGADIVVQS
                     THKTLPAFTQSSMIHIQGDRVDIDKILNMLRITESSSPSYLLLSSLELAVDIYENKGK
                     ELMEELLNNIRIFKDKVDSNINIYDTNDKTKIFISSKNMGLTGYELENILRNKYNIQV
                     ELSNYYGVLLICTIGNTAEDFSSLETALNNVVKEDFKFEKLENKKYPVVIPKKILTPR
                     EAFYKTKKSVKIYDSIGKICGECIVPYPPGISVISPGEVISKEIIDYLMFCHSKGMIV
                     SGLKDVDLNFIQVIDLEDI"
     gene            1996..2685
                     /locus_tag="PC466_000241"
     CDS             1996..2685
                     /locus_tag="PC466_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate kinase"
                     /protein_id="HDF2767677.1"
                     /translation="MKGKLIIIESGSDASGKATQTEILYERLKKEGYMIKKVEYPNYE
                     SPSSALVKMYLKGDFGKNASDVDPYIASTFFTADRYASFKTDWEEFYNEGGIIIADRY
                     TTSNMVHQASKMDICDREEYLNWLADYEFNLFKIPQPDCVIFLDVPIEFSKKLMENRK
                     NKITGEEKKDIHESDIEYLEKSYNNALYIADKYDWKKINCVLDNKLRSIESIHNEIYK
                     IVLDSIKPMER"
     gene            2688..3623
                     /locus_tag="PC466_000242"
     CDS             2688..3623
                     /locus_tag="PC466_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HDF2767678.1"
                     /translation="MYFENIIGQDFAKKYLTNSIKKNKLNNAYMFEGMDGIGKKKFAD
                     ELSKLLLDYENLENSPDYVLIKPDGNSIKIAQIRNLQSDIVIRPHKDYKIYIINNAEK
                     MTVEAQNALLKTLEEPPNYAIIILVTNNKESLLETIKSRCDIIKFSPIPIEDLKRYLI
                     NTGIEEERAQLLAIFSRGSIENALNLSQSSEFSMMREDIQQYIQIMLDKNIVEILNIP
                     NNMEKYRGKIIALLDMMINYFRDIILLKENVNKNMLINVDKLVFIQNMSGKISYSQLS
                     KIIDIIEDAKSKIKSNCNFNISIQVMSLNIYEVIK"
     gene            3620..4513
                     /locus_tag="PC466_000243"
     CDS             3620..4513
                     /locus_tag="PC466_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HDF2767679.1"
                     /translation="MIKIVGIRFKSAGKIYYFDPVDFNIEQDMDVVVETARGLEYGKV
                     VVGPKDMDESELVSPLKPIIRIATEEDKKVYLENKEKAKETFELCQQKIKEHELTMFL
                     IDCEYTFDRNKLIFYFTAEGRIDFRELVKDLAAIFKTRIELRQIGVRDEAKSIGGLGP
                     CGRKLCCSSWLGDFQPVSIKMAKDQSLSLNPTKISGICGRLFCCLKYEHDVYSEAIEK
                     MPVVGALVQSDDGKGKVVEVNPLLEQIKVEFQDKTVKIYTREDIKILREPKKCDGCGG
                     KCKDNDGLDEATLRELKKLED"
     gene            4591..5337
                     /locus_tag="PC466_000244"
     CDS             4591..5337
                     /locus_tag="PC466_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HDF2767680.1"
                     /translation="MQLKDSERIDDLQLKGLKIIQDTNGFCFGIDAVLLANFTKIKKD
                     AKVVDLGTGTGIIPILIAGKSEAKKIIGVEIQEDVYEMATRSIKLNGLEERVEIINED
                     IKYIDKVLDINGYHVVTSNPPYMHIDGIKNPNDKKAISRHEVRCNLEDVIRASSRLVM
                     PRGKFFMIHRPTRLVDIITLGRKYKLEPKVIQFVHPRPQKAPNLVLVQFVKDGRPELK
                     ILDPLYVYGEDGNYTKELKAIYNNKDIGEL"
     gene            5338..6171
                     /gene="rsmI"
                     /locus_tag="PC466_000245"
     CDS             5338..6171
                     /gene="rsmI"
                     /locus_tag="PC466_000245"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HDF2767681.1"
                     /translation="MSGKLYICPTPIGNLEDITYRTLRTLKEVDLIAAEDTRHSIKLL
                     NHFEISKPLTSYHEHNKDSKGDYLINKLIDGENIALISDAGMPGISDPGEEIIKQAIQ
                     NNIEIEVLPGATAFVTALVGSGMDTHRFVFEGFLDRDKKVRKAQLEELKEESRTIIFY
                     ESPHRLKDTLKDMLKILGNRNISINRELTKKYQEIIRENIETTIKIFEEKEVRGEFVL
                     IVEGFHGEKSKKENYDGLTDREYVLKLIESGMNKKDAIKIVCKDRKLKKDVVYKQVLD
                     L"
     gene            6194..6898
                     /locus_tag="PC466_000246"
     CDS             6194..6898
                     /locus_tag="PC466_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing protein"
                     /protein_id="HDF2767682.1"
                     /translation="MEIGKIIIESLKREDTHKIFIELDNKHELEKIIPKISCMKSVGE
                     CKYHVVNCFEHSINALKELEIVLNDKDFFPIHLRKHVSNYLNTYIEEGINKLHVLKLG
                     TFLHDIGKPDSMTLDETGRVHFTNHEKIGAQIIDNMGIKLELSTETYRLISKYVRYHM
                     ILLSLYKKNDLSRKELINVFNLVDEDTIGVIMLGYADIVSTVKLLGKSGEVSVLKTYM
                     EYILTNYLYKSNYTHV"
     gene            complement(7086..7514)
                     /locus_tag="PC466_000247"
     CDS             complement(7086..7514)
                     /locus_tag="PC466_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007287587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HDF2767683.1"
                     /translation="MDVTDYRIIEILQDDGRISMKDLGKIVGLTSPAVSERVKRLEES
                     GVIEGYKAIVNPDSLGRVIKAFIHISLPSNGYTEFIESAAKDPRIVECHHITGDDCLL
                     LKVIVKDMYELENVIDTIKKIGSTKTSVILSTPIQAKSIL"
     gene            complement(7551..8981)
                     /locus_tag="PC466_000248"
     CDS             complement(7551..8981)
                     /locus_tag="PC466_000248"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HDF2767684.1"
                     /translation="MRNLTLLTDLYQLTMLNGYFEKNIHEDIVVFDMFFRKNACDGGY
                     TIVCGIDQVVEYIDNLHFSDEDLEYLKNLNLFSDKFLKFLKEFKFTGDIYAVEEGTIM
                     FPNEPLITVKAPLYQAQLIETALLTIVNFQSLIATKASRVCFAAQGDPVFEFGLRRAQ
                     GPDAGIYGARAAVVGGCAGTANVLAGKMFDIPIIGTQAHSWVQKFDNELEAFQAYADV
                     YPDKCLLLVDTYDVLNSGVPNAIKVFKNISEKGYKPMGIRLDSGDLAYLSKEAKKQLD
                     NAGFSDISITASNDLDEYTITSLKAEGATINSWGVGTKLITSFDSPSLGGVYKLAASC
                     EKGVLEPKIKISENPEKINNPGYKKVIRIYNEDNKAEADLIMLHDEVIDESKPLEIFH
                     PTYTWKTKVFTNYKVKELLKPLYIKGRCKYNKKAVLEIKNHVQYELSTIWEQYKRLSK
                     PHIYKVDLSRNLWYLKTQMIDSKKVL"
     gene            9113..9697
                     /locus_tag="PC466_000249"
     CDS             9113..9697
                     /locus_tag="PC466_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore maturation protein A"
                     /protein_id="HDF2767685.1"
                     /translation="MIIIGKIWFYMVSIGIIGSLISKNMGELNKVILSETSKGIEFAI
                     SLAGIMALWMGIMNIAKESGLIEKIGQKLNPIMRRLFPSIPKGHKAMSYIVMNIALNM
                     LGAGNGATAFGLKAMSELQTLNNKKDTATNDMIMFMVINISSIQIIPFTIIKLRMDMG
                     AQNPSEIIFTTLFATIISTAVAIITCKFFQRRYR"
     gene            9713..10234
                     /locus_tag="PC466_000250"
     CDS             9713..10234
                     /locus_tag="PC466_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore maturation protein"
                     /protein_id="HDF2767686.1"
                     /translation="MEIFSNLLIPIIILYIVVYGKYKKIDVYDSFVKGAIDGLKAAWD
                     ILPYIIGIFLAIGIFKTGKGLDMLEWLFTPIANMMSIPKELIGLISVKPLSGSGALGM
                     YSELANRVGIGSLVEKMGATIVGSSETIFYTMAIYYGSLKIKNTRHTLSCAMISHVAG
                     VIAAVFICYVIFV"
     misc_binding    10300..10546
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            10630..12567
                     /gene="metG"
                     /locus_tag="PC466_000251"
     CDS             10630..12567
                     /gene="metG"
                     /locus_tag="PC466_000251"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HDF2767687.1"
                     /translation="MSKPSFYVTTPIYYPSGGLHIGHTYSTVAADTIARFKRFCGYDV
                     KFLTGTDEHGEKIQKKAIEQGMSEIEYLDGMIKDIKALWNTMDISYDDFIRTTEKRHT
                     DIIQKIFTKLYEQGDIYKGEYEGRYCTPCESFWTESQLLEGNKCPDCGRETYLVKEES
                     YFFRLSKYEDRLKELFKDDSFCFPAARKNEMVANFLDKGLEDLSVTRTTFDWGIKVPF
                     DEKHVIYVWVDALCNYITALGYMTDNDEEFKKYWPANVQIVGKEIVRFHTIIWPALLM
                     ALGLEVPKQVFGHGWILFADDKMSKSKGNVVYPEPIIERYGIDTLKYFLLREFAFGQD
                     GSYTHRNFVTRINYDLANDLGNLISRTVAMVEKYNNGIIPTAKVSTDFDADLKEQAVS
                     TRENFEAEMDKMQFHEALESVWKLVRRTNKYIDETMPWALAKDETKKDELDTVLYNLC
                     ESIRIIATLINPIMNETANKIYEHIGIKGQDDITTWESTKTFGLIGENVKVFKGEPLF
                     PRLDVEKEIEELTKMFSGKPPVEEKPLEHKEEITIDDLDKIELRVGKIISCEKHPKAN
                     KLLVSQVKIGPETRQIVSGIAEYYKPEDLVGKEVTVVCNLKPVKLRGVESQGMILAAG
                     DDGDPYVLPFTQGAKDGCEVR"
     gene            12597..13367
                     /locus_tag="PC466_000252"
     CDS             12597..13367
                     /locus_tag="PC466_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HDF2767688.1"
                     /translation="MLFDSHAHLNDESFDEDRDELIGSLKDKGVDLVVNPGADIETSI
                     TAIELAKKYDFIYSAVGVHPHDVSKLDDTAIETLRKLATENEKVVAIGEIGLDYYYDY
                     SPREEQKEWFKKQIELANELKLPIIIHDRDAHGDTFEIIKNTKNPEIGCVLHCYSGNV
                     ELAREYVKMGCYISIPGTVTFKNNKKTREVVREIPLERLFIETDSPYMSPEPHRGKRN
                     NPSQVSFVADKIAQEKGICYEEVCRVTKENAKKFFNIK"
     gene            13704..14135
                     /gene="phnG"
                     /locus_tag="PC466_000253"
     CDS             13704..14135
                     /gene="phnG"
                     /locus_tag="PC466_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnG"
                     /protein_id="HDF2767689.1"
                     /translation="MYTVDSTKILINMNLEKLEKIYSMIKDTSSISIIKEPNLATVMV
                     RANESVKNTTFNLGEILVTECSVKVDESLGYGIVSENNNKKAIYLAVIDAVLHSNNSK
                     FDELKNYINKSVYEENLRYEQEIIDEFSLINKTKVQFNAMD"
     gene            14150..14725
                     /gene="phnH"
                     /locus_tag="PC466_000254"
     CDS             14150..14725
                     /gene="phnH"
                     /locus_tag="PC466_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnH"
                     /protein_id="HDF2767690.1"
                     /translation="MVNYTQEIYRKMLDSASFPGKLNNIDNINIENNTKLLNGAIGIA
                     ITLLDQEVTFYIENYTQKDIKNIRALTVSNQIDYRKSDYIFLDINSEVDILQIKIGSF
                     EYPDESATIVHQVNDLSTYSQTKYIKLDLSGPGIKSKNSIYINGIREEFIERLSTINK
                     DYPIGIDLILVDKKGEIAFIPRSSKLSWEVL"
     gene            14728..15813
                     /locus_tag="PC466_000255"
     CDS             14728..15813
                     /locus_tag="PC466_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-phosphorus lyase complex subunit PhnI"
                     /protein_id="HDF2767691.1"
                     /translation="MAYVAVKGGEEAILQAKNILEFYRVKGDSLPIDVKQIEEQMSYA
                     VDKVMSEGSLYNKELSALAIKQAQGDILEASFYVRALRSTMPRITYSEPINTEEMRIK
                     RRISATFKDIPGGQYLGATRDYENRILNVELLEEDEKKNRDFRDSFINELETVDEIPE
                     FTKISNIFRKENLLQEEVCENKLEEVIDDITRNSLRFPVSRSAKLQALTRGESGVVSG
                     FAYAIVRGFGDEHPYISELRTGNVFIKVKHPIYEDEEIIIGDMLVTECEIVSKASQNK
                     TENSKTNSEDKNKMSLGYGLCMGNNENKAISMAILDKSLEPNSEKLAQDEEFVLLHID
                     GIDSLGFISHFKLPHYVDFKADVERIK"
     gene            15833..16702
                     /locus_tag="PC466_000256"
     CDS             15833..16702
                     /locus_tag="PC466_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-D-ribose 1-methylphosphonate 5-phosphate
                     C-P-lyase PhnJ"
                     /protein_id="HDF2767692.1"
                     /translation="MIYNYGFLDENTKKEIRRKILKAISIPGYQVPFGSRELPIAKGW
                     GTGGLQLTLSLIGKNDVVKVIDQGSDDSTNACNIRSFIASVSNVETTKDTLEATLIQT
                     RHRIPEEKLKSNQILIFQVPIPETLRIVEPSEVETRRMHSEEDYSRMWVYLYEDIVRF
                     NDISIAVEYPCKVNDRYLMNPSPIPRFDIKKLNMSDNLFLFGAGREKRIYAIPPYTKV
                     EPLEFEDYKFEEEKFEGKYCSLCNSTNTFLDEVYDSDTNEKYYSCSDTSYCEKVRLKN
                     NSIDVTIGGTWNE"
     gene            16695..17561
                     /locus_tag="PC466_000257"
     CDS             16695..17561
                     /locus_tag="PC466_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2767693.1"
                     /translation="MSKINVSKRLENIDKQVLIGRNINLIYGDGCEKCFESTGYESNN
                     ICKYCGSIVACNNVNLELYEGEVLGIVGESGSGKSTLLKILFFQEHANSGEVYISHYN
                     KDTNILELSDQKKRYIKNHFMGIVYQNPHLGLNLDFSSGGNIAEKLLMANLYNVEKIR
                     DRGKELLIKTNIPVERIDHKPKYFSGGMQQRVQIAKALSNNPPILLLDEVTTGLDVSV
                     QAEVLDLIREIQRELKISMIVVSHDFDVIKMLADRTIVMKNGSVIESGLTDQIMEDPQ
                     HPYTQQLINSLL"
     gene            17602..18315
                     /locus_tag="PC466_000258"
     CDS             17602..18315
                     /locus_tag="PC466_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF2767694.1"
                     /translation="MKETILEVNNFSKDFELHALNKTITACSNISFEVSKGEFLGIIG
                     KSGAGKSTILKSIYKTYIPTTGEIIFNSEIYGNVDLAKIGDREMINLRKKEIGYVSQF
                     LKTLPRITAIELVVHSLIESGFEKDCSYDMAKDILNQFEIKENLWDAYPNNFSGGEKL
                     RLNLAQAMVKKPRLLLLDEPTASLDNQSKIYVKEKMLELKSQGTTMIGIFHDIEFMET
                     VIDKTFTMAKGTISESGVA"
     gene            18316..19485
                     /locus_tag="PC466_000259"
     CDS             18316..19485
                     /locus_tag="PC466_000259"
                     /EC_number="3.6.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-D-ribose 1-methylphosphonate
                     5-triphosphate diphosphatase"
                     /protein_id="HDF2767695.1"
                     /translation="MIKLIHNANIVLEDMILENGHLIIEGDTIKKVSNDRIDYAFDFN
                     EIDEIIDAKNLYVIPGIIDIHSDAIEKEIEPRPSTLLPFNMAFYELDKKLPANGITTV
                     YHSISLGDGVGVRSIDNSLKMIKNIDSYKNIDSKSINHKVHLRYEVLYYEGLEKVLEL
                     LDENKIDYLSIMDHSPGQGQYTNPTFYKEYATKVWGVTENYVDTWLDDLVNLHDNLDW
                     NKIANIIGIAKTKNINVASHDDDTLEKMDFIKNIGINVSEFPITLEVAKHSKKLGVLT
                     CLGAPNIVRGKSHNNNLKAMDAILEDCCDIVCSDYLPSAMIKSMCIVAERINNLNKAV
                     SLFTSNPAKAVGIYDERGSIKENKKADLVLVDIDSEYPKVLNTIVNGKTVYKREV"
     gene            19489..20325
                     /locus_tag="PC466_000260"
     CDS             19489..20325
                     /locus_tag="PC466_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HDF2767696.1"
                     /translation="MLTELHCHTSISDNNFTTEEIIKKAAEKNINILAITNHDTLSGL
                     DEALVLGEHYGITIIPGIEISAYDYKNRKRVHILGYNIDLNSQEIKNLCNPMVCDRHK
                     ASVKMVNKIIDLGYKISLEDVKKYSSKTGIFKQHIMKALIDKGYTDNIYSSLYKELFH
                     RGNGKVYVSLKYVDYRDAIKAIKNSGGICVLAHPGQMDNFSAIEEMVKVGLDGIEVYH
                     PSHNKELEKESLSYAKKYNLVVTGGSDYHGFYSQHNYELGSKSLNKEDLFKFRLALGG
                     VL"
     gene            20326..21321
                     /locus_tag="PC466_000261"
     CDS             20326..21321
                     /locus_tag="PC466_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF2767697.1"
                     /translation="MSFLQVKNVGKSYGQVKVLKDISIDIEKGEFICLLGPSGCGKST
                     LLRIIAGLEDKHGGKIIINDKDMTNSPPESRNFGIVFQSYALFPNMNVYKNIAFGLEN
                     KNISKSNIDKKVKEVLDVVELSGYEKKYPSQLSGGQQQRVALARAIALEPDFLLLDEP
                     LSALDAKVRLKLREQIRSLHRKLGITTIMVTHDQEEALCLADKMVVMNRGEIIQVGTP
                     KEVYKNPETPFVADFIGTINFIDDGINKIAIRPEDIKVESNRDSKDKDIKVGEILDIE
                     FRGFNYRITVEYRSKQMKLDVVSKVAEQMKLCIGSKINFKIPKEGIVQYKSEGCA"
     gene            21339..23027
                     /locus_tag="PC466_000262"
     CDS             21339..23027
                     /locus_tag="PC466_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     permease subunit"
                     /protein_id="HDF2767698.1"
                     /translation="MITSKNKRRISDSTIQKYFLIFSVIVLIVFILFPLVSLLKNAFM
                     DTSGNFIGISNFSKYVENPSLIASFKNSIFVSTVSSLISLCLAFIYSYAITRTNIKFK
                     DFFKTMGMFPLFAPTMLYGISLIYLFGNKGIFTTMGLEVPLYGPLGIIISQILFTFPQ
                     AFLILSVALSMADYRLYEAADSLGASEFKKFCKITIPGIKYSLLSSFFVSFILAFTDF
                     GAAKVVGGNYNVLATDIYKQVVGQFNIPMGATVSMVMLIPVLIAFTLDKMASKKQGMT
                     ITAKSMPYKIKENKFRDRVFLIVCSFITLLIFILIFVSVIGSVIKLWPYNLSFTMEHY
                     TFKGILGSGIKTYLSSLKISTLTAIFGTIFVFFSAYIIEKVDKFPKLRQTAYLLSMIP
                     MALPGLVLGISYITFFNSASNPLNFLYGSTAILVIVNVVHFYSVCFITSNSSLKMLDK
                     EYELVAKSINIPFYKVFFNITVPMSITSILEIVVYYFVNSMVTVSALIFLYIPQTQTA
                     SISILKLDEIGYIGPSAAMAVLVLLTNIIVRLLYEFVTKKLKNNTQKWQQKDVA"
     gene            23039..24106
                     /locus_tag="PC466_000263"
     CDS             23039..24106
                     /locus_tag="PC466_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HDF2767699.1"
                     /translation="MKFKKLVSLGVLSTLLLSVITGCSTDSSGSDSKSDSKTKGDLTV
                     YTAIEEDSIEPYLATFKEKYPDIKLNIVRASTGDITARLLAEKDNPQADVVWGVAATS
                     LLVADDQGMLEPYAPKGSEEIESAFKDDKEVPSWVGIDAWMTGITVNTKELSDKNIPV
                     PSSYEDLIKPEYKGLISMPNPSSSGTGYLTVSALIQIMGEEKAWQYMDKLHENIGVYT
                     QSGSAPATSAASGEYPIGISFGYRGIKLKEEGYPVEVVFPKEGSGWDIEANALVKKDN
                     IKEASKVFLDWAISKDAMNEYSKNYAVTTISTGNPIPEGFPKKPLEQMIDNDLKSAAK
                     NREDILNKWISKYDGKTEKES"
     gene            24592..24708
                     /locus_tag="PC466_000264"
     CDS             24592..24708
                     /locus_tag="PC466_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter ATP-binding protein"
                     /protein_id="HDF2767700.1"
                     /translation="MDDDINMIAIRPEDIRVEFNRDFKEIIDLKLRPYRYKN"
     gene            24872..25939
                     /locus_tag="PC466_000265"
     CDS             24872..25939
                     /locus_tag="PC466_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HDF2767701.1"
                     /translation="MKFKKLVSLGILSTLLLSVITGCSNVSSGSNLKSNNKTKGELTV
                     YTAIEEDSIDTYLATFKEKYPDIKLNVLRLSVGGITARLLAEKDNPKADVLWGVAATS
                     LIILDDKEMLEPYAPKGFDKVNPAFKDDKKVPSWVGIDAWMTGITVNTKELKAKNISA
                     PNSYEDLIKPEYKDLISMPSPASSGTGYLTVSELIQIMGEEKAWQYMDKLHKNIGVYT
                     QSGSAPAILAASGEYPIGISFGNRGIKLKGEGYPVEVVFPKEGSGWEIESNALVKKDN
                     IKEASKVFLDWAISKDAMNEYSKNFAVTTIDTGNPVPEGFPKNPLEQMIDNDLKSAAR
                     NREAILNKWIEKYDGKTEKES"
     gene            26131..26661
                     /gene="rnmV"
                     /locus_tag="PC466_000266"
     CDS             26131..26661
                     /gene="rnmV"
                     /locus_tag="PC466_000266"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HDF2767702.1"
                     /translation="MIKEIIVVEGRDDVTAVKRAIDAELITTGGFGFPKGVMQRIKAA
                     NERRGVIIFTDPDFAGEKIRKKIASEVPGCKHAFLPREEAKKDGDIGIENATPQSIIA
                     ALNKVRTENTEKRDEFKQVDLIRNGLIGNEEASLRRDALGKILGIGYGNAKQFLNRLN
                     NYGVEREEFIDALKQI"
     gene            26832..27701
                     /gene="rsmA"
                     /locus_tag="PC466_000267"
     CDS             26832..27701
                     /gene="rsmA"
                     /locus_tag="PC466_000267"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HDF2767703.1"
                     /translation="MDRLSSHNATKEVVQKYNFKFSKSLGQNFLIDSNIIDKILSGAR
                     ITRGDNIIEVGPGIGTLTREMGKIAEKVVAIEIDRNLIPILKDTLSDLDNTEVVNQDI
                     LKVDIQELVKDKLNGGPVKLVANLPYYITTPIVMKFLEEDIPVTDIVVMVQKEVADRM
                     NAIPGTKDYGALSIAVQYYCDTEIVAKAPRHMFIPQPNVDSTVIGLHVRDKRKYDVHN
                     EDIFFKTVKASFGQRRKTLLNSLGGLGFLNKDEIREILKEANIDEKRRGETLSIEEFS
                     VLSNIINTKVSSK"
     gene            27767..29038
                     /locus_tag="PC466_000268"
     CDS             27767..29038
                     /locus_tag="PC466_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2767704.1"
                     /translation="MGSKRKFKRDYIILEAKDINFRYKERVLPKAFAKVEVNDEKAII
                     ALYVENLKYVKDGYKAVAIKDDHGLIDLGNIILNEQGRGEFVLDLEDSDDEIKGIALL
                     YERNIPLIGFKGNKLENYEDILFQEVEEEEYEEYEEYEELEEDEEIEDNEESDRDEDS
                     EEEYIIEEYDEDEYEDYWEDDEDIEEGELKARTEVEDSGDEEIEEFNNYKEIENYNRV
                     KVQEEYIDIEYDEEEEEEEEVFEVNREEDRFVSSKPTKSKKVQKDQNNIEKIKRANGV
                     SQGESGNKQTSTLLMPRQIKKGLKLFKEVKPFVTDYIDKTRWWKIEINPTTLCGYTMP
                     YLGYLNVLNYTMYSDAVLHSYKYRHYLFGVQYDEYNKRKHYIYAIPGNRNEQPDNGST
                     GFLRYQACDNRTNSLGYWLCFIDSRQRNIVR"
     gene            29189..30304
                     /locus_tag="PC466_000269"
     CDS             29189..30304
                     /locus_tag="PC466_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HDF2767705.1"
                     /translation="MINEQRILNEFLELVQIDSLSLKEGNVAKVLVKKLEEIGCSVVI
                     DNAGEKANGETGNIIATLKGNKEGKKILFSSHMDTVTPGIGVKPIVDEANGIIKSDGT
                     TILGSDDKAGIAAILEGLRYINENNIEHTDIQVVFSICEECGLVGAKNLDYGKIDSEY
                     AFILDSGGSPGEIIVKAPAQDVINVKILGKTAHAGLEPEAGISAIMVAARAIENMNLL
                     RIDEETTANIGIINGGTATNIVTGEVNIVAEARSLKENKLDVQTKHMVETFEKAAKDF
                     GAQIEIDVNRAYTPIDVSEDSEIIKLAKKAFSNLGIEGHTESTGGGSDTNILSKNGIE
                     AITLGIGMKNAHTLSEHIAIKDLYDSAKMVVEIIKEA"
     gene            30490..31386
                     /locus_tag="PC466_000270"
     CDS             30490..31386
                     /locus_tag="PC466_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HDF2767706.1"
                     /translation="METRYEEANKITIQSILWNVVLTIIKVIAGVIGNSSAMIADGLH
                     SASDIISSIGVLIGNYVSSRPGDREHNYGHEKAETLVSFVLSILLIFVSITIGIEAIK
                     SLFNLDALSVPSILPLVVSVISILIKEYQYRITIKVAKKINSPALKADAWHHRSDALS
                     SVAAFIGIGGSILGFKPLDPIASIVVAIFVAKVGISILISSVNELMDVSVDEEEIKEL
                     KFIVADTEGVKNLGDIKTRKHGAMAYVDLTICVDENLTVKQGHDIATKLEKHIIKHME
                     FVKGITVHVEPCTNCQGNKCNN"
     gene            31456..32253
                     /locus_tag="PC466_000271"
     CDS             31456..32253
                     /locus_tag="PC466_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2767707.1"
                     /translation="MSKKRKLKKKAAILIGVVVFFIIYFISFRIGINMEKDKSEVPKK
                     VEKEEEDNRSLRTQIKEKKKVYISDKNIENIKIEEDMWDEIKLFFSDFKKVRNTTSSY
                     EAVYEGYSDDGVKFSTDLNFFRVYTVNKEEYYKVPVSSKDAFKKLLDESIYTSFDLLS
                     HYKDWKEVTITHGKEIKKVHRWKFDDLAHKMISKRVVGKVQPEKSKERSDYNFTINIK
                     GDNFDVKVDTMGKDYVKVTSKKNVSYYEVHTSLFDYLKNEIFEIGKK"
     gene            complement(32309..33661)
                     /locus_tag="PC466_000272"
     CDS             complement(32309..33661)
                     /locus_tag="PC466_000272"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HDF2767708.1"
                     /translation="MNIHFIGIGGISMSALAEICINKGYQVSGSDSNESYLLDKLRDQ
                     GATIYIGQKKDNISDDVNMVVYTAAVHPDNEELVAAKEKNKLVMNRATFLGQIMREYK
                     NSIAVSGTHGKTSTTSMLSTIFEYADLDPTILVGGNLSMIGGNVKIGNSNHFITEACE
                     YVDSFLNFNPKISIVLNVEEDHLDYFSGIDEIKASFNKFGKLLPPEGYFIINGDDENI
                     DDILYDVKATIIKYGRDSDNDAVIKDIHFDNSGHGIFRIEYEGRDLGEFELSVYGLHN
                     IYNASSAIMAALVSGIDLETIRKNIKIYKGVGRRFETKGYYKNALVVDDYAHHPTELK
                     ATLAAAKKLKKSTLWCIFQPHTYTRTKSLLGEFSEAFYAADKVIITDIYAAREKDPGD
                     IHSKDLVEKLYQNNVDAIYIKEFEDIVKYLRENVKDNDLVITAGAGPIYKVADLLVEK
                     "
     gene            33880..34758
                     /gene="purR"
                     /locus_tag="PC466_000273"
     CDS             33880..34758
                     /gene="purR"
                     /locus_tag="PC466_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HDF2767709.1"
                     /translation="MKFKRTERIGAIVKILSDNPNKIYTLSYFTNQFNAAKSTISEDL
                     LVVKNVFEKLHLGKVITISGAAGGVKYIPKTSIAENAEFLMELCERICDKSRILSGGF
                     LYLIDLIYDPTIAAKIGKIFASNIEYVDADYVVTMETKGIPMALMTAKAMNLPLVIIR
                     KDIKVSEGPTLSMTYVSGNSSKVESMSLPRKALKPDSKVIIIDDFMRGGGTIKGMVDL
                     MNEFGAEVIGTGVFISTTNPSEKMVKDYISLIQLDVNGDKIVVEPNLKTFKDEYRNED
                     LDEEEDSEFEFEIDED"
     gene            34914..35192
                     /gene="spoVG"
                     /locus_tag="PC466_000274"
     CDS             34914..35192
                     /gene="spoVG"
                     /locus_tag="PC466_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation regulator SpoVG"
                     /protein_id="HDF2767710.1"
                     /translation="MKITDVRVRKLTEEGKMKCIVSITFDNLFVVHDIKVIEGHNGLF
                     IAMPSRKVGEGNFRDIAHPINAEMRQVLEDAVLQAYHEALVQWEVAAE"
     gene            35402..36781
                     /gene="glmU"
                     /locus_tag="PC466_000275"
     CDS             35402..36781
                     /gene="glmU"
                     /locus_tag="PC466_000275"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HDF2767711.1"
                     /translation="MNFKAIILAAGKGTRMKSKYPKVIHKVCGKEMVNHIIDVSKKSG
                     VKDTVVILGHEAEVVKEKLAEEIIIAMQTEQLGTGHAVKMAKEYINDEDTIVVLCGDT
                     PLIKEETLKRLFEYHIENKYHATVLTTRVGNPTGYGRIIRDKKGDLLKIVEQKDANSE
                     EKMISEINSGIYCFNGKSLREALDLLNNNNSQGEYYLTDTAKIMRDKGLKVGAFAGST
                     IEELMGVNSRVELSKAEEIMRRRINESHMVNGVTIIDTNSTYIESDVMIGNDTIIYPG
                     VMLQGKTRIGSDCIIGMNSSITNSEIGDGTEIKNSTIIDSKVGENSNVGPYAYLRPKS
                     DLGNNVKIGDFVEVKNAIIEDGSKASHLSYIGDAHVGKNVNIGCGVVFVNYDGKNKFK
                     SVVKDNAFIGSNSNLVAPVVVEEKGYIATGSTITHDVPDGALAIARERQVIKEGWVEK
                     KNQKDDQSK"
     gene            36876..37826
                     /locus_tag="PC466_000276"
     CDS             36876..37826
                     /locus_tag="PC466_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003361732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate pyrophosphokinase"
                     /protein_id="HDF2767712.1"
                     /translation="MNTSGSEIKIIAGNSSKELAQKIADYIGVSVLDCEVGTFSDGEI
                     CVNMNETVRGCDVFVVQSTNSPVNDNLMELLILIDALKRASAGRITAVIPYYGYARQD
                     RKAKARDPITAKLVANLITAAGADRVLTMDLHAAQIQGYFDIPLDHLLGGTILANYFN
                     EKKIEDLVVVSPDLGSVTRSRKFANTLNGEVPIAIIDKRRPKANVCEVMNLIGDVKGK
                     NVILLDDMIDTAGTIVNAANALKEFGAKDVYACCTHGVLSGPAIERIANSEISELIVL
                     DTIQLPEEKRIDKIKIKTVAPLFGDAIRMIFSNESVSKLF"
     regulatory      38666..38751
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            38913..39434
                     /locus_tag="PC466_000277"
     CDS             38913..39434
                     /locus_tag="PC466_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HDF2767713.1"
                     /translation="MKLKKNKKGFTLVELLVVIAIIGILAVVAVPALFSNINKAKVAS
                     VESDYSSVKSAALSYYSDTNKIPVTPDGQTGLSVLETYMESLPDKADIGGKYKLIKVG
                     NKLVLQIGTNDEGVTLTEAQSAKLLSDIGENKIYTSVTADNLGNPLTSNTKVDNKVLY
                     IVLIDNTVMDSTK"
     gene            39585..41261
                     /locus_tag="PC466_000278"
     CDS             39585..41261
                     /locus_tag="PC466_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HDF2767714.1"
                     /translation="MAKKVRIGDKLVEKGYITEDQLKWALSEQKNSGKRLGEFLVQEG
                     LIDSNLLISVLKELLDIESIFLEGTEIDTLATKMVPENICKRYTVFPFKIDGNKICLA
                     MSDPQDREAVQDVRRMSGKDVEIFISSTEDINKAIGHAYAHSEINKAMTEYNKNRTGG
                     VRETVILEEDVNAAPIVRLVNNILENAVRMEASDIHIEQSENYMRVRFRIDGMLREYM
                     RMNSAPYKAVISRIKIMSDINISEKRIPQDGRIYLKVDNKPIDFRVSTMPTNRDEKIA
                     MRVLDKSNFMVSKEVLGIDEHGSKIYDELINTPYGLILVVGPTGSGKTTTLYSMLNQL
                     NTENRNLLTIEDPIEYELPGVNQSQINEKAGLTFASGLRAFMRQDPDIIMVGEIRDTE
                     TAEIAIRASLTGHLVLSTLHANTAVGAISRLLDMDVESFLITSSVLGVISQRLTRKIC
                     EHCKVSYEADIGEKKALGIDVNESVTIYRGKGCERCNNTGYKGRLGIFEMLEITPEIK
                     ELIDSSANQREILKMARKQGMVSLKEDIVKKVLNGKTTVEEMIRIILMTD"
     gene            41273..42481
                     /locus_tag="PC466_000279"
     CDS             41273..42481
                     /locus_tag="PC466_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HDF2767715.1"
                     /translation="MKSFKYTVIKEDGKKQTDVIEANDFNEARNLLRKRNLRVIEIKE
                     SKNKNIRLSSRKRKKDLGADQISHFCRQFAIIVSSGINSISGLETLARRSTNITLREE
                     INRIVAEIKVGSTIADSMLSSKSKFPKLLGAMVATGEATGKLDEVLKSMASFYASEHR
                     VKQKLRNAATYPLIVLISSFIMIFIFTTFMVPKMINSITTVGATLPLITRIVMGFGMF
                     MKKFWIIVLLVIILFIYQFKKYLKTSVGRAHKDRVINKIPVLGKGINCMVATRFSRAL
                     YLFVSTGYPLVQGLDYIIDSVNNTMAEKILASAKDGITRGEGLAENLERYTYFDSVLV
                     QMIAIGEQTGELENISRQMAEFYEYESEIYLNRMASMIEPVLIIAVGIIVAILVVSIF
                     MPMLSIYDAM"
     gene            42496..44208
                     /locus_tag="PC466_000280"
     CDS             42496..44208
                     /locus_tag="PC466_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PilN domain-containing protein"
                     /protein_id="HDF2767716.1"
                     /translation="MNKVYVSYYGDSISIVEGRYKHDKDKFYVKNFNVFSIEDIAQDF
                     SKEKYALLRYALENVKLKSRHVVFCLNTRDVILKPQKLPNMDKKDLDGFMKLEMDEMM
                     ALESDEYVFSYEVSSETHDNSDGDESSLNLIIGAIQKEEVNAIVEIMHEFDLVLDRID
                     TLSTAYLRMLKNLDYNDIMVTNISDNSTIINIYKKDTLFISDNIPIKITAKDMDMQLL
                     NVVEESKGLMNYYSSRNFGKVTDTILILGKRYSNKLIYETFSSAFSSYVSQGLTEIMD
                     ISDMITGDIDEDDINSIVELLGSMIEPKGKRDFENINFLPMDILRKQIKAKQMKNILK
                     IAPIVILILAIPYLCLIFSNNLANKELENVNGEIRNIESAYYQIGNIEKMIQSKSEEI
                     KVYDMLIGKKVKWENLLDDIDKNTPSKVELTSLSTTYQNLGTNNKADNSKSNKTTTDK
                     SSNNETKSSTKSDSNGDKTDNDLNEDKTTNVSEALTGNSETNSNNTDKDDKTPLYDKI
                     PNVINIEGNAKDSSYVGQFLYKLKGLYYFKDVKLHSIKSNAEDSNYTFSMTLYLKEGV
                     LTNE"
     gene            44201..45109
                     /gene="pilO"
                     /locus_tag="PC466_000281"
     CDS             44201..45109
                     /gene="pilO"
                     /locus_tag="PC466_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 4a pilus biogenesis protein PilO"
                     /protein_id="HDF2767717.1"
                     /translation="MNKDIFKKDIKDIFKMEVSLKGILIKVIILLAILSYGYFGLYPQ
                     YQKYIATKNSVKQATEKLNIYKEKTALMPKYEKQLEEVESELKEKSKNLLYDMQDGLF
                     LIGLDKKMKAYNIDLTSYDVGNVKEYEHFYGISTTISVRGDYRNVKKLMAYLEEQKNV
                     TQILDYTMTSYIEPEKEEEETTNNKDLIKNVNINKDTKIYWVEGENKWHLYKDCPLIK
                     EGEILKNDKLLDRSTNYLCNTCVLRAATEKEAKKEVVAPKAEGVVDATFKFIMYTKEN
                     TTMILDTDNPSSWRPGKYNPFKSSAK"
     gene            45136..45702
                     /locus_tag="PC466_000282"
     CDS             45136..45702
                     /locus_tag="PC466_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HDF2767718.1"
                     /translation="MSLYKNNEKGLTLLEVIIAVFILTIVLSISYKVFNGITSAVKKQ
                     QIITDAQVNINLINKYLNRDLENCKELTKTGSGNNYEYNIEMPDNVVKYEVSIETKKN
                     TEVYSVTRIQNNTIDTENEVREEIIYNQPLVQNNKEMKETPFKIEKQTGKSIYTVSIY
                     YNESVQESHKNSNLNNKTYTFDVMSRIG"
     gene            45739..46266
                     /locus_tag="PC466_000283"
     CDS             45739..46266
                     /locus_tag="PC466_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HDF2767719.1"
                     /translation="MSKKNSERGFSLIEVLVAMAIMGIVLFAFFNIINTNNKANTKND
                     TDITSLNYVQSEIENLREKIKSGEFDFDSLDKLEDGTVVYEKLIDKSKKVVYDKVLSE
                     GDVSLYDTPYEKITTIKDEDGNLIDKGNITNKIKTIVEDKSGQIYKIAVTGKSMNDYS
                     SKKEVKIVTEIFKDK"
     gene            46287..47825
                     /locus_tag="PC466_000284"
     CDS             46287..47825
                     /locus_tag="PC466_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2767720.1"
                     /translation="MRKWNKFKSERGAALVLVLIVVALLSIVGLIFSNQIANRIKSTK
                     TTNEGIQAKYLAETCVENSIDKAYEKLYDELEKMDNEFKSENQEKSISRSKLRNISDE
                     DFNNQDEKNIEAERLGYMNNINFYLNKASSDLEKASMELKKLYDLDMLDYRDIEYVDA
                     NIISHRDSILEICKNYTSGDISKINEYILKEDIDSTTLIEAKLVNNDILLKMFLEENK
                     IENEHLNSAFSHTYKALDNISLAMQNMIEYRHTFHIDEPKVEVSNGIPDSQQYYELIQ
                     NPIINSMEYIWNSKWDTLENLLEILPNQTQGFNSLRVHLRNNVRKFEKLSDNISSGKK
                     NTAKNFLKYKELLYEISDQCNQLKSMSYEKIPVKYDNMALITTFDYIQNELLAEIKCR
                     LKELKPQEIDKTEGITIKIPFYKADYDMTKEGWPKLKENGSGAELSLMVTGDKDGIKE
                     VEVTDGKKNIIGLGVEENSNSKYKVDAIVNFNLNIDTNVVGNYDIKDKILINHDISSY
                     KKVN"
     gene            47925..49007
                     /locus_tag="PC466_000285"
     CDS             47925..49007
                     /locus_tag="PC466_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilus twitching motility protein PilT"
                     /protein_id="HDF2767721.1"
                     /translation="MYIYDLLEQGIRLNASDIHITVGTNPVARVKGGFVKLSEQILTS
                     EVTMQMAKDIAGESIFKVIEEHGEADFSASLKTGERFRVNAYRQKGNYAIAIRTITAE
                     IPTFEKLGLPESIKSFTEKHKGLVLVTGPTGSGKSTTLASMINIINEKQQKHIITLED
                     PIEYVHHHKQSLVNQREVGTDTESFHSALRAILRQDPDVILIGEMRDPETVSIALTAA
                     ETGHLVFSTLHTVGAAKTIDRIVDMFQPSQQQQIKTQLSTVCEGVVSQQLLPTADGKG
                     RIAAIELMFATPAIKNLIREGKTYQIPNMIQTGVKVGMKTMDQDLMELYKNGKITKDM
                     ALSRCTDQEFMTRMIGGVNYNGYYNR"
     gene            48988..49770
                     /locus_tag="PC466_000286"
     CDS             48988..49770
                     /locus_tag="PC466_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HDF2767722.1"
                     /translation="MDIIIVNLYVFIVGIVFGSFFNVCIFRIPEGISISRPPSHCMSC
                     NTRLKPIDLIPVLSYLMSGRKCRYCYEKISSRYAIVELITGILFLTVFMLYGISTSTI
                     YYLVLVSLLIIITFIDIDHFIIPDKILIFGAIFSMIFNLLFKEIPVKDSILGVFICGG
                     SVWIIVLLIEFVIKKECMGGGDIKLFAMLGLYMGVKNGLLTALLSVYVGAVYGICVII
                     ISRIKGKEYNSVIPYGPFISIGALITILCGKQLLELYFSMVI"
     gene            49872..50522
                     /locus_tag="PC466_000287"
     CDS             49872..50522
                     /locus_tag="PC466_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HDF2767723.1"
                     /translation="MEYIIIISLFFAHLINKSLCVFCDREKKNLYNTFFIYIITVVLS
                     VLIYLKFGISVECVQYMVLIPFLIIISIVDYYTIYVYDITIVSGIIVQGIIFLAFFNI
                     AQFDYINHIFGLLIGFIIPYIIAKLTKGLGYGDVGLYSLCCFALGNNYGFYVIVLSFI
                     LAFLFFIILYITKIFKDVDIRKQIPFTPFISLSTILIIFTEYNIFNFYYNLLYKFI"
     gene            50536..51096
                     /locus_tag="PC466_000288"
     CDS             50536..51096
                     /locus_tag="PC466_000288"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HDF2767724.1"
                     /translation="MYVVVGLGNPGKKYEKTRHNVGFDVIDILAKEYNISVTKIKHKA
                     LIGEGRVGTEKVLLVKPQTYMNLSGETLIDIYKYYKVDLSNIVVVYDDIDLEVGKIRI
                     RKKGSGGTHNGMKSITKCLGSNDFPRVRVGVSKPEAGQDLADFVLSRFRKEESDNINE
                     ALEKAADAIDSIIRENIDMSMNKYNG"
     gene            51113..54499
                     /gene="mfd"
                     /locus_tag="PC466_000289"
     CDS             51113..54499
                     /gene="mfd"
                     /locus_tag="PC466_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HDF2767725.1"
                     /translation="MNDVFLYPLQNSKEYKDIINCIKNTKGSLLVNGLLPVQKPHISY
                     SIFNDLSRQMIFITSSDLEAKKVYEDLSFYMEDKVEYLGFQDIYFYHLDAKDRNEEAK
                     KLKVLLKLANKEKIILVTSIEAVLRKYIPKQVLLDSVSHYKVGDSLDLEKLTEKLVSL
                     GYERVSKIEGFGQFSIRGGIIDVFSLEYTNPIRMELFDDEIDSIRTFDVYSQKSIDKL
                     QQFSITPSREFIYPEKTTDALVKLKKETTKNTDEGTFQNIDYISSKTYFEGAENYIDY
                     IYPEENKSIFTYLADDAIVFINDITRLKERCENYINEFRENYKLNLERGLAIKNQGKL
                     LYHYTDLEYLVKDKSVVLNSLLPKSINNFSIKSIINFESREVPTFNGKVDLLVEELNR
                     LKYNGYKIILATNTLERANKLGKDLLDKGLETTISKDRDIEIKSSQVIIVPAHINSGF
                     QYKSIKFVVITDNEMIGVYKRASKTSNKKVKKGKKIESFLDLSVGDYVVHENSGVGRY
                     TGIEQITVNAIKKDYMKIVYQGGDNLYVPIDQMDKVQKYIGAEVEKVKLNKLGTNEWT
                     KAKAKVKKEIEDMTKDLIELYAKREKIQGYKFSKDTPWQAEFESLFPYQETEDQLKAI
                     EETKKDMESSKVMDRLVCGDVGYGKTEVAIRSIFKACMDQKQVAVLVPTTILAQQHYN
                     TFKERFENYPLRVEVLSRFKTPKQQKQIIEDAKKGLVDILIGTHRIISKDINLPNLGL
                     VVIDEEQRFGVKHKEALKKIKSTVDVLTLSATPIPRTLHMSLSGIRDMSVIEEPPQER
                     HPVITYVTESKESVIQDEIERELSRGGQVFFVYNRVEHIEEMASMIQKLVPDARVAVA
                     HGRMTSKSLENIILGFLNKDYDVLVCTTIIETGMDISNANTMIIYDADKMGLAQLYQL
                     RGRVGRSSRQGYAYLLYEKDKTLSEIAEKRLKAIREFTEFGSGFKIAMRDLEIRGAGN
                     ILGSQQHGHMAVIGYDLYVKMLNDAIKKVKGEPIVEEIDVEIDLSVNAYIPDNYIKDE
                     LIKIEMYKKIASIENKEDMLDIQEELEDRFSDIPKPVQTLLTIAYIKSLCKILKIEKI
                     RQLKDEILLVPITKYRTKQKIGYNIVTELEELLEKMCKVK"
     gene            54530..55525
                     /locus_tag="PC466_000290"
     CDS             54530..55525
                     /locus_tag="PC466_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HDF2767726.1"
                     /translation="MKKVITLVIAMILVVSVTACSSSKGETVATVEGTKISSDEFKKT
                     IALYKDSMEQTYGKDIWDKEVEKGVKYKDKFKDLILDQLITTEVIYSQAKKDNLLPKK
                     EDVEKSFKELKDAMGKDEKYKEQLKKLGIDDEFLRDQQEKDLAMQNYQSNFAKKTKIS
                     DEEMKKYYDTHKDEFKKDEVEASHILLKTVDDNNKPLSDKEKAEAKKKAEEALKEVKS
                     GEDFAKVAKKYSQDTSASDGGKLGFFSRGQMVAEFEDAAFSMKKGEVSDLVETQYGYH
                     IIKVTDRINEQTSFEDAKETIKDQLLKNKYQEQIEKLTKEAKVEKDEKVINKITI"
     gene            55649..56188
                     /gene="spoVT"
                     /locus_tag="PC466_000291"
     CDS             55649..56188
                     /gene="spoVT"
                     /locus_tag="PC466_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein T"
                     /protein_id="HDF2767727.1"
                     /translation="MKATGIVRRIDDLGRVVIPKEIRKTLRIREGDPLEIFTAKDGEV
                     ILKKYSPIGELNEFSQEYAETLAEVLGYGVLITDLDSIIAVSKLPKKDYKEKSISDEL
                     EAIISERTVKYSKDKNILPLFKEDQKEYTSQVIMPIISASGDCIGSIVVVSKDKDTIA
                     ESEEKSLKIAANFLGKQVQ"
     gene            56308..57921
                     /locus_tag="PC466_000292"
     CDS             56308..57921
                     /locus_tag="PC466_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HDF2767728.1"
                     /translation="MNNNKNKDSFLKGALILGLAGVIVKIMGGFFRIPLGNMIGSEGM
                     GYYQAAYPVYTLFLTLATAGFPTAVAKLVSEKVAIGNFKGANKIFKVSHTVLFITGII
                     SFCILFFGADYIVTNVMKNPGALYSMKAIAPALLFVPAMSAYRGYFQGRQDMTKIAVS
                     QVAEQFFRVVLGLTLAYLLMKSLGQTFGAAGAISGATIGSIASMLYLVFAYMLGRKER
                     RAEIDASQRFKDERVSYIFKKLLTVAIPITIGASVMPLVNMIDNVIVIRRLMEAGFTY
                     KVANSMFGQLTGMAMATINLPAVITTAMSMSLVPAISKAYALGNKSKARKDTKSAVKV
                     TLLIVLPCAFGMASLAIPIMGLLFPHEPSSVGTILFTLTPCVLFLGLIQTLTGIIQGM
                     GKPIVPVIALCVGMLCKIVISYTLTGIPDINVLGSAFGTVTAYFVAAMINLLYVKKHM
                     NVNFSKKEFIIKPFITVMTMFIMVKLSYGALVGFLGNSISTIIAICVGGIVYVVVILG
                     IGGIKKEEILTMPKGDKLYKLLKKVKLIR"
     gene            58028..59476
                     /gene="mazG"
                     /locus_tag="PC466_000293"
     CDS             58028..59476
                     /gene="mazG"
                     /locus_tag="PC466_000293"
                     /EC_number="3.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphate pyrophosphohydrolase"
                     /protein_id="HDF2767729.1"
                     /translation="MGKISIVGLGPGDYSLISQGVLESLINSPKVFFRTEKHPIIDKL
                     KETIQYTSLDYFYEKEENFDNVYLKISEFIIEESAKGDLVYAVPGHPRVAEKTVSIIE
                     RLANEKHIAVEILPSMSFVDAMFNYLAIDPSEGFKLVDAFEIENSYIDLDTSMIITQV
                     YDKFIASNVKLKLMEHYDYNQEVCIVNGAGVKDLESKKFIKLCELDRNENFFDYLTSL
                     YIPKSSKKMYNTVHDLEIIVNTLRSPSGCEWDKKQTHQSLKNSVIEEAYELCNAIDNN
                     DIDEMVEELGDVLLQVIFHCQIGNEEGYFDLKEVVNGICKKLIHRHPHIFSGAKLDMS
                     KFEKTWEELKKEEKGESTITDGLRRIPKHLPALMKASKVQHKAALVGFDWDNVEDVFK
                     KIEEEYQELLDEHRVGNIKYIKEELGDLLFSIVNLARFLDIDSGEALNCTTEKFINRF
                     DFIEKSAMNLNKKLEDMTLEEMDEFWNQAKKQ"
     gene            59565..59843
                     /locus_tag="PC466_000294"
     CDS             59565..59843
                     /locus_tag="PC466_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003153447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HDF2767730.1"
                     /translation="MNKAELVSKMAEKSGLTKKEAEAALNAFMSSVQDALVNNEKVQL
                     VGFGTFETRERAARQGRNPRDPEQVIDIPASKAPVFKAGKGLKDIING"
     gene            59915..60157
                     /locus_tag="PC466_000295"
     CDS             59915..60157
                     /locus_tag="PC466_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HDF2767731.1"
                     /translation="MRLDKFLKVSRIIKRRTVAKDACDKGIVTINGKVAKSSSEVNIG
                     DTLEIQFGEKKMKFKINEVKEHVLKNDAKEMYEILE"
     gene            60219..60473
                     /locus_tag="PC466_000296"
     CDS             60219..60473
                     /locus_tag="PC466_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein YabP"
                     /protein_id="HDF2767732.1"
                     /translation="MEQNITLKDRSKLVISGVEHIYSFNDKRVELKTSVGEMVIEGEN
                     LDMSKLSIDENIISIDGTINSMVYAKPKKPQESFLKKVFR"
     gene            60474..61007
                     /locus_tag="PC466_000297"
     CDS             60474..61007
                     /locus_tag="PC466_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2767733.1"
                     /translation="MIPFTQDVSIFYATIYGGILIGVLFDFYRGLRGNFKFINYFAII
                     FDVLFWFLATVIIFVTINLTEFFDLRYYHFVALFIGFILYYNTISKIVLSIINKIIRF
                     VRNSFKKVTHYIVSFLNNLYYVIIYSLHLLFDIIFYIPNIFIATRKSIKRKSNKKLKN
                     KKKSKPKKKKNKTKKRV"
     gene            61013..61297
                     /locus_tag="PC466_000298"
     CDS             61013..61297
                     /locus_tag="PC466_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HDF2767734.1"
                     /translation="MNLRKKFSGQIIVISLFLGISIFSMMTGFVFEYTKAKEYKKEIA
                     SLNKQLKKTEIQINSLKKDEKSYEGDLEDIARKRLNMVKPNETVYVDINR"
     gene            61410..62330
                     /locus_tag="PC466_000299"
     CDS             61410..62330
                     /locus_tag="PC466_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ppx/GppA family phosphatase"
                     /protein_id="HDF2767735.1"
                     /translation="MKVGAIDIGTNSMRLLIADYRDGNFINRKKFVNTTRIGYGVDSK
                     GYIKEDAIKRNIKALKEFSDKCNDEKCEKIYCMGTSALRDSKNGDYFVKLAKEETGID
                     VDIVTGIEESNLGFKGVLEGIQGDDTIIVIDIGGGSTEFIVGDSEGIKFNKSENVGAL
                     RMTERFLKHDIIEDEEFEAMSSFIYDEIDKTLNHIKDRGLKTLIGIGGTITSLSAMNQ
                     ELEIYSMEKIHNSKIHKKEIEEILQKLIKMTLSDKKNLKGLQEKRADIITAGVKILNI
                     IMEKLEIEEITVSEYDNLEGLICQKSKKMY"
     gene            62420..64792
                     /gene="spoIIE"
                     /locus_tag="PC466_000300"
     CDS             62420..64792
                     /gene="spoIIE"
                     /locus_tag="PC466_000300"
                     /EC_number="3.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein E"
                     /protein_id="HDF2767736.1"
                     /translation="MQRSVAVVKNKTVKPNVIKLISGYIDFTTAAFAVMGFLLSRSII
                     VDSVAPLGIAFFICASKIDKYKIPVFISTLLGILLSSNDFGNVAKYAVCLTIFMAMNK
                     KLKLSDSIAKVAFIGAIILLPISMGQAFFSNRYVYGLLIAGVEAIIMFISIYVFSYGI
                     GLMANVNNRMSVRTEEAISISLLLTFSIMGIGDISLFGISIRTILSTVLILLTSIVGG
                     ATMGASSGVIIGVASILNNMTSAVYMGIYSFSGLISGAFNKINKYFCILGYILSWTII
                     YLYTSGITSNMMQLRDILLGCLIVLVLPERLFNKIEKLIKSNVASNEIVYDYIMRSKN
                     LTNSRLNSIYKTYDDLADTFDKIREKDKVLDQRDIANVIDMIHNDECKSCSMRRMCWE
                     SRFNHTYTMIYNILEKIEEKGELSLNDIPKNFRKECMKPESIVKISNHYYKMFVLDYD
                     WSVKFSESRKLIANQIRSISKSIKSLSQDLEGDIMLDIEKEKNIYEQLERYDITVDKV
                     SYLTKSNNEFEISIEKKTCHDGCMCEDKIVNIISDLVGENMSVRKIGCHCLGGKCKAT
                     FVKSQKYKAVTEVSAMSRDGHILCGDNYTYMEINDGKYMMAISDGMGKGKKAYEESSA
                     TIDILEKMIDAKIKDEIVIDTINNMLLLKSSEEMFSTLDLGILDLKRGCLETIKMGAC
                     STYIKREDGEVDLISSSSLPVGILSDVKIDRKNVKVKEGDYVIMVSDGIVDAGRNNNL
                     GDNWLIYFLKNIETTNPKEISNLILDRALELQALQIEDDMTVLVTKICTK"
     gene            65143..67035
                     /gene="pepF"
                     /locus_tag="PC466_000301"
     CDS             65143..67035
                     /gene="pepF"
                     /locus_tag="PC466_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HDF2767737.1"
                     /translation="MNRKLCKAIIPLFISIFCMLIISIKADQGYQKNNDRAIAVMNNN
                     DTEDDAEKKQEVDYEKTCWNLQSLFKSDDQWKKELKSFDKDTKELKNYIGKVTKSPTH
                     LSFALNIKEKLDIRLNKLSAYVKLKQDTNKNSYKYLDMSDSMSKSYGNYMGICSDLEL
                     EILKLSNKDYKKIISNKNINRKYGAYLRDIRRNKVHYLDDKSEDILSKVSSISSLPSQ
                     VYELFRNMDRKTNLTPAQYASELESVDRENRKKAYQDELITYNDNINTIAGLITGQVK
                     KNIFYSQERGYESSLEMYLESDNVDEKVYNNLIRTVNSNMDSLHKYIDLRKKVLKLDK
                     VHSYDMFVPMVKAVDNNINYEKAQSIVYSALSPLGKEYNDVVYKAFNEKWIDVYSHEN
                     KVSGGYCLSVYENHPYILLNYNNSLGSVSTLSHELGHAVYEYLSSKNQNYFNSNPSIF
                     THEVASTTNEALLYEMLIKEAKGNDEKAYYITQYLDLIKDTLYTQTMYAEFEKTIHEL
                     VEKGKSVNALVLNDVWGQLLKKYYGQSYELDQLSKVGWARIPHFYNSFYVYKYATGCS
                     AGVSFAQDILKNGSDNYMSFLKKGSSDYPINLLKSSGINLTNTKPIENTIKKFDSLVA
                     ELEKLL"
     gene            67149..68114
                     /gene="galU"
                     /locus_tag="PC466_000302"
     CDS             67149..68114
                     /gene="galU"
                     /locus_tag="PC466_000302"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HDF2767738.1"
                     /translation="MQVKVKKAVIPAAGLGTRFLPATKAQPKEMLPIVDKPTLQYIIE
                     EAVASGIEEILIITGRNKKSIEDHFDKSVELELDLEKKGKKELLEVVQNISNMINIHY
                     IRQKEPKGLGDAIYCARHFIGDEPFAVMLGDDIVDNDVPCLKQLTDAYEEYRTTILGV
                     QKVNQEDTNKYGIIEAKNIEGRVYKVKDMVEKPESGKAPSNIAILGRYIITPEIFDIL
                     KDLPPGKGGEVQLTDALKILSKKEAMYAYNFEGKRYDVGDKLGFLEATVDFALKKEDL
                     KEDFIKYLKHVCSEFDKNNNVLYNNTDEKIDLIEVNEARELEIQK"
     gene            68614..70218
                     /gene="rho"
                     /locus_tag="PC466_000303"
     CDS             68614..70218
                     /gene="rho"
                     /locus_tag="PC466_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HDF2767739.1"
                     /translation="MRRIFLILDDKVLEGLGSKTLVELREIAKELKIKSITTYKKNEL
                     IEIINSKSKNEEKVNEETKEKNEDIKEDIKNRKENIERESIEKEVEYKSPTKSYNKKE
                     IDTQNISQNQENRNQRNDYNKTTSVNDSNKSSNISNRMVRNNNKNYYMPKQVDESKIV
                     DEFNTSKEDEVVGVLEILPDGFGFLRGSNYLSTEGDVYVSPSQIRRFNMKTGDKIKGI
                     TRHPKSGEKFRALLYVQKINDENPDTAIQRNAFETLTPIFPEERLTLETNRNEIATRI
                     IDLISPIGKGQRGLIVAPPKAGKTVLLKSVANSIAKNHPNVELIVLLIDERPEEVTDM
                     KESIEGDVIYSTFDQVSSHHVKVAEMVLNRAQRLVEHGKDVVILLDSITRLARAYNLT
                     ISPTGRTLSGGIDPGALHGPKKFFGAARNIRQGGSLTILGTALVETGSRMDDVIFEEF
                     KGTGNMELHLDRKLAEKRIFPAIDIYKSGTRRDDLLLDDEEKTALWRLRREMSNNSVM
                     EITDKVIELIKRTKDNKEFVKSIKNL"
     gene            70371..70571
                     /gene="rpmE"
                     /locus_tag="PC466_000304"
     CDS             70371..70571
                     /gene="rpmE"
                     /locus_tag="PC466_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018591942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L31"
                     /protein_id="HDF2767740.1"
                     /translation="MQKEIQPKYNPVEVRCACGNTFVAGSTKDEIKVEICSECHPFYT
                     GKQKNIEKGGRIDKFKKRFKMD"
     gene            70716..71609
                     /locus_tag="PC466_000305"
     CDS             70716..71609
                     /locus_tag="PC466_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1385 domain-containing protein"
                     /protein_id="HDF2767741.1"
                     /translation="MAKQAVGGQAVIEGVMMQSKDKRAVAVRKSDGEIALKEDRIKSW
                     VRDKNIDKIPFVRGSFVMIDTMIQGIKSLNFSSEFFMEEAEEDKFDLFIKKIFKDKAN
                     DIIIIFSLVIAMLLSAGLFIFIPTLVGGAFSKVMPNDFMLNLIEGIIRIAILFAYIVL
                     ISRSKDIERVFQYHGAEHKSIYCYENDLELTVENARKFKRLHPRCGTNFLFIVMAVSI
                     ILFAFFGWPNPILRIFMRIICVPIVAGLSYEVIRVLGKYDNGFTKIIAYPGMMLQYFT
                     TKEPDDEQLEVALEALKAVVD"
     gene            71627..72475
                     /gene="prmC"
                     /locus_tag="PC466_000306"
     CDS             71627..72475
                     /gene="prmC"
                     /locus_tag="PC466_000306"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HDF2767742.1"
                     /translation="MTIKDIIIKYSDKLKDISDTPRLDTELLLQKTLGVDRLYIHLNL
                     NKELTEEQKTKFMGFAEERLNGRPIAYIVENREFMGLDFFVKEGVLIPRPDTETLVEE
                     IIEICREKKDVSILDIGTGSGAITISLAKYIENSKIMSFDISETALEIAKKNAIINEV
                     GEKIKYINSDLFTAISDSNIKFDIIVSNPPYIKKQDIETLHKQVKDYEPYNALEGGED
                     GLDFYRRITEQGKKYLNKCGILAYEVGHNQAEDVINIMKSNGYKKIYTKKDIQGIDRV
                     VIGYNI"
     gene            72519..73583
                     /gene="prfA"
                     /locus_tag="PC466_000307"
     CDS             72519..73583
                     /gene="prfA"
                     /locus_tag="PC466_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HDF2767743.1"
                     /translation="MLKKLEVLEDTYKDLSEKIGDPDVINDQKVWQKYIKEHADLEPI
                     VMKYREYKSVLDSIKESKEILQEESDEELRELAKMELAEMEEKVAPLEEEIKILLLPK
                     DPNDDKNVIVEIRGGAGGDEAALFAGDLFRMYSRYAERRRWKIELLSASDTGVGGYKE
                     VSFMIKGKGAYSRLKYESGVHRVQRIPSTESGGRIHTSTSTVAVLPEVEDVEVEINPN
                     DLRIDVFRSSGNGGQSVNTTDSAVRVTHIPTGEVVSCQDGKSQLKNKEQALKILKARL
                     YDKALAEQHKDIAAERKSQVGTGDRSERIRTYNFPQGRISDHRINLTLYKLDAFLDGD
                     IDEMIDALITVDQTEKMTAI"
     gene            73712..74392
                     /locus_tag="PC466_000308"
     CDS             73712..74392
                     /locus_tag="PC466_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HDF2767744.1"
                     /translation="MILKVTIIGLLAGVIGTGLGGVISAIFKREVDKYLSFFMGLSGG
                     IMLAVVVFDLMKESMDKMGIINTVIFTFVGALITMYIKTKLDVSGNMASGYLIFISIL
                     LHNLPEGLAIGSSFMSTESLGITLAIVIGLHNIPEGLAMALGLVCNKMKLSKVILFTV
                     IAGLPMGLGSFLGVYFGGVFTSLIGVFLATAGGTMMYVVLEEIFPHSKSVYCIIGFLL
                     GTMIVNYI"
     gene            74421..75461
                     /locus_tag="PC466_000309"
     CDS             74421..75461
                     /locus_tag="PC466_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HDF2767745.1"
                     /translation="MKTIISNIDINNIDYEEIKIQAKLLREGKTVIFPTETVYGLGAN
                     ALDENAVKKIYEAKGRPSDNPLIVHIYEKEEVYDLAKDISDKAKLVIEKLWPGPITII
                     LNKKDIIPYKTSGGLDTVAIRMPSNVIARAIIKEAGIPIAAPSANISGRPSPTKAKHV
                     YEEMNGRVDGIVLGGDSNFGLESTVLDLTEETPMILRPGSITKEVLEELLGEVKLDPS
                     LSKKEDNQKAKAPGMKYKHYSPNADVYIISGKRENVATKINDMIKSNRDKGLKTGVMC
                     ISRNREFYDGEVIDLGNSLEEVASNLFDALIEMDKKGVDVIYSEEFPKTGVGQAIMNR
                     LLKSAGYKVIKA"
     gene            75478..75927
                     /locus_tag="PC466_000310"
     CDS             75478..75927
                     /locus_tag="PC466_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight protein arginine
                     phosphatase"
                     /protein_id="HDF2767746.1"
                     /translation="MNILIVCTGNTCRSPMAEAILRKAIKESGRSIEEYSISSAGIST
                     ANGMGASENSIEVLKEIGIDLSNHRSKVITKKLIDESDIILTMTKSHKEILVQAVPKC
                     KEKVYTFKGFANKNEEDISDPFGGNLDIYRSTMREIMYSVNEIVKKI"
     gene            75944..76396
                     /gene="rpiB"
                     /locus_tag="PC466_000311"
     CDS             75944..76396
                     /gene="rpiB"
                     /locus_tag="PC466_000311"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose 5-phosphate isomerase B"
                     /protein_id="HDF2767747.1"
                     /translation="MKIGLGCDHGGYNLKKEIISYLESKGIECVDYGTNNATDSVDYP
                     VYGEIVANSVINKEVDYGILCCGTGIGISLAANKVPGIRCAVVSDVFSAKMSKAHNDA
                     NMLSLGERVLGKGLALEIVEAWINTDFEGDRHARRVNMIKSIEEKHNK"
     gene            76432..77061
                     /gene="upp"
                     /locus_tag="PC466_000312"
     CDS             76432..77061
                     /gene="upp"
                     /locus_tag="PC466_000312"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HDF2767748.1"
                     /translation="MSKVVETNHPLIQHKLTLMRDKNTGSKDFRELLTEIAMLMGYEI
                     TKDIPLKDVEIETPIQKTSSKVVAGKKLAIIPILRAGLGMVDGLVSLMPAAKVGHVGL
                     YRDPETLKPVEYYCKLPQDIGERDIIVVDPMLATGGSAVAAIDLLKSKGAKSIKLANL
                     VAAPEGIAEVQKYHDDVDIYVASVDERLNEHGYIIPGLGDAGDRLFGTK"
     gene            77361..78176
                     /locus_tag="PC466_000313"
     CDS             77361..78176
                     /locus_tag="PC466_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EF2563 family selenium-dependent molybdenum
                     hydroxylase system protein"
                     /protein_id="HDF2767749.1"
                     /translation="MKNCIAVRGAGDLATAVIHKLHNSGFKVVALEIEEPLAIRRQIS
                     FCEAVYEKKVTVEGVECIFCNTEKEIEEVLSQHKVALIIDPKGEKLSKLNPIVLVDGI
                     LAKKNLGTTKDMAPLTIALGPGFCAGEDVDVVIETMRGHNLGRIITNGRAEKNTGVPG
                     AIKGFSKERVMHSQYDGIMENVCKIGDIVEKGDLLCYINNYEKKHEVRATISGVLRGL
                     LKDGAKVNKNLKILDIDPRKEEVKNAFTISDKARCIAGGVLEAILNNGIYPQN"
     gene            78402..78839
                     /locus_tag="PC466_000314"
     CDS             78402..78839
                     /locus_tag="PC466_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dCMP deaminase"
                     /protein_id="HDF2767750.1"
                     /translation="MRPSWDEYFMEIAEVVKKRSTCIRRQVGAVIVRDKQILTTGYNG
                     SPRNLEHCENIGCKRQELNIPSGERHELCRALHAEQNAIIQAAHNGISVDGATLYVTT
                     RPCVLCAKMCINAGILKIVYEGDYPDDMSTELLKEAGIELIKF"
     gene            79024..79251
                     /locus_tag="PC466_000315"
     CDS             79024..79251
                     /locus_tag="PC466_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AtpZ/AtpI family protein"
                     /protein_id="HDF2767751.1"
                     /translation="MSKRNTHTEIAKLFSLISQIGLMIVISILGCTFLGKFLDSKLNT
                     TPVLTIIFLLLGVGGAFSGVYKTLIVYTRRK"
     gene            79256..79642
                     /locus_tag="PC466_000316"
     CDS             79256..79642
                     /locus_tag="PC466_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase subunit I"
                     /protein_id="HDF2767752.1"
                     /translation="MDIKLLNQVRSVTKGIVIFDVVLIVLMLITSTLSKPVLLGLIFG
                     SIIAMLNFRLLAISLEKSVTFPAGKAQAYASAQYAIRLFIMAVVLIASATVPHLNIIG
                     TALGLLSTKFVILSKNFINKLKRKEA"
     gene            79645..80349
                     /gene="atpB"
                     /locus_tag="PC466_000317"
     CDS             79645..80349
                     /gene="atpB"
                     /locus_tag="PC466_000317"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HDF2767753.1"
                     /translation="MNQAHYYLIGNFKISETILVSWGIMAFLAIASYFLTRNLKKVPT
                     SKVQIFLEFAVGGLAKMVTDVMGKNTVKRMPYMIPYIGSLFLFFACSNLSPLLGLRSP
                     TTDLDTTAAWAMITFFMIYFAGVKFKGLSYFKELAQPLAIMLPINIIGELARPISLSF
                     RPFGNILGGTIIMGLFYQLLGFISSLIPGLSIPIGEILIPVPLHLYFDLFAGLLQAYI
                     FIMLTMVFISSAGELD"
     gene            80418..80678
                     /gene="atpE"
                     /locus_tag="PC466_000318"
     CDS             80418..80678
                     /gene="atpE"
                     /locus_tag="PC466_000318"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HDF2767754.1"
                     /translation="METAIVAAASAIGAGIAVATGIGAGIGQGIAAAKAAEAVGNQPE
                     AKGDITSTLLLGVAIAESSAIYGLVISIILLFVNPFFKYLGM"
     gene            80801..81298
                     /gene="atpF"
                     /locus_tag="PC466_000319"
     CDS             80801..81298
                     /gene="atpF"
                     /locus_tag="PC466_000319"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HDF2767755.1"
                     /translation="MEKALVGITWEFVFQIVNTFIIFLLLRKLLFKPVLNIIESREND
                     IKSDLAEGEKAKNEGLALKKEYESKINFAKDEGQEIIKQATIRAEQKSDDIVNTAKKD
                     ALDIKEKANKDIEQERQKVINEIKNDISNIALLAASKVIEKDLDKSKHEELIENFIKE
                     VGEAK"
     gene            81295..81840
                     /locus_tag="PC466_000320"
     CDS             81295..81840
                     /locus_tag="PC466_000320"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HDF2767756.1"
                     /translation="MINVIANRYAEALFQLGEEENSTDVLFKELEKVVDMMTKVSKDF
                     YKVLKSPLVSKSEKKNLVEIIFSKEVSSNIKNFLKVLVDKDRISYLEDIELAYKELLN
                     KKNNVIDGVAISAIPMSETDIKELEVKLSNKYNKNVTIENVVDKTILGGVLVRIGNEQ
                     IDGTVKTRLDKMKEKLSEVIS"
     gene            81857..83359
                     /locus_tag="PC466_000321"
     CDS             81857..83359
                     /locus_tag="PC466_000321"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003405060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HDF2767757.1"
                     /translation="MNLKPEEISSIIKQQIKNYENKVELTDTGSVLTVGDGIASVYGL
                     EKAMSGELLEFPGEIYGMALNLEEEVVGAVILGDDSEIKEGDIVKRTGRIVEVPVGEA
                     LIGRVVNSLGQPIDGKGPIAYTKTRPVESEAPGIIDRRSVYEPLQTGIKSIDSMIPIG
                     RGQRELIIGDRQTGKTSIVIDTILNQKGKDVICIYVAIGQKRSTIAQLVSSLEKGGAL
                     DYTIVVSATASESAPLQYIAPYAGAAMGEEFMYNGKHVLIVYDDLSKQAVAYREMSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDELGGGSMTALPIIETQAGDVSAYIPTNV
                     ISITDGQIYLQPELFYSGVRPAVDPGISVSRVGGSAQIKAMKKVAGTLKLAYSQYREL
                     AAFSQFGSDLDEDTKKRLAQGERIVEILKQGEHQPIKVENQVMIIYAVINNHLEDIPI
                     DNIARFESELYAFVDNNYPEISRKILGGEDFTHDLTDAINEFKEKFVVEV"
     gene            83387..84265
                     /gene="atpG"
                     /locus_tag="PC466_000322"
     CDS             83387..84265
                     /gene="atpG"
                     /locus_tag="PC466_000322"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F1 subunit gamma"
                     /protein_id="HDF2767758.1"
                     /translation="MAGAGIKAIKTRMGTVESTKQITKAMELVASSKLRKAKEKAEDS
                     REYFNTLYNTVKDIAQTTRGIRNEFLKEREVKNKCYVVVAGDRGLAGGYNSNVLKESV
                     SHMKGKKETVITVGKKAHEFFSKRNYNIAKDINSVEACGYEDATEISQTIIDLYKKGE
                     VDEVYIAYTKFKSALSQEVEILKLLPLVFEKDTDEQGMAVKEEKQNRSKVQYIPSAEA
                     VLSYIVPQFISGTVYGGILESFASEQGARRTAMESATDNANEMLSNLELSYNRARQSA
                     VTQEITEIVGGVEALK"
     gene            84278..85672
                     /gene="atpD"
                     /locus_tag="PC466_000323"
     CDS             84278..85672
                     /gene="atpD"
                     /locus_tag="PC466_000323"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HDF2767759.1"
                     /translation="MANVGKVVQIVGAVLDVKFDSEQSLPNLLNALVIKLGDKEIVAE
                     VAQHIGDDTVRCIAMSATDGLVRGMEVVDTGGPISVPVGDETLGRIFNVLGKPVDGKP
                     APKSAPKLPIHRPAPAYDELETTAEILETGIKVVDLLAPYLKGGKIGLFGGAGVGKTV
                     LIQELINNIAKQHGGISVFSGVGERTREGNDLYGEMSESGVINKTALVFGQMNEPPGA
                     RMRVALTGLTMAEHFRDEQGQDVLLFVDNIFRFTQAGSEVSALLGRMPSAVGYQPTLA
                     TEMGALQERITSTKKGSITSVQAVYVPADDLTDPAPATTFSHLDAKTVLSRQISSLGI
                     YPAVDPLESTSRILDPSIVGKEHYEVARGVQSILQRYKELQDIIAILGMDELSDEDKL
                     IVARARKIQRFLSQSFTVAEQFTGNPGQYVPVKETVRGFKEILEGKHDDLPESAFLFV
                     GTIEDAVRKAKGSM"
     gene            85675..85935
                     /gene="atpC"
                     /locus_tag="PC466_000324"
     CDS             85675..85935
                     /gene="atpC"
                     /locus_tag="PC466_000324"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F1 subunit epsilon"
                     /protein_id="HDF2767760.1"
                     /translation="MASEFSLKVVTPSNTFYDGDVEMIVVRTTKGDKGVLKGHIPFVS
                     GIPVGTLKIKKEGSFKEAKIAEGFINVTQDKTVILTESAEWI"
     gene            86397..86777
                     /locus_tag="PC466_000325"
     CDS             86397..86777
                     /locus_tag="PC466_000325"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HDF2767761.1"
                     /translation="MNIFDIGVDIIEIDRIRKAVDKNNRFLEKIFTDREIEYFNSKNF
                     KAESIAGNFAAKEAISKSIGTGIRLFNFKDIEVLRNEMGKPIVKTYNNLAKMCIDYNV
                     LEIKVSISHSKDYAIANAITIIKD"
     gene            86792..87253
                     /locus_tag="PC466_000326"
     CDS             86792..87253
                     /locus_tag="PC466_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HDF2767762.1"
                     /translation="MMDKTAKEIMTTDVIVAKQDDSIADVANMLIAEKIGGLPVVDSE
                     NRVVGIISETDILKKEKYIEAPLYINLLQGLIFLDDLKKVEKDIKQVAAYKVGELMSK
                     DIIKVHEDDKFDDVANVMIKKSINRVPVVDDDNKLKGIICRYDIIKALYNE"
     gene            87274..87864
                     /locus_tag="PC466_000327"
     CDS             87274..87864
                     /locus_tag="PC466_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2767763.1"
                     /translation="MRKKWTIVCIMFLALVIIVIGCQKRQSTKEEVYKDFQKQISDMN
                     YYSCKAEVEVVGNKSPHNYVLIHTYKKTDNYKLEVISPKHLKGKSIEYQGDKILVKNP
                     KISDVVELPNTGKNNQYLFVGDFIKNYLQNEEMKVKLSKGHLVLETFIPGDNKYFNKQ
                     VLYVNADTKNPEKMEVLDKEGVPRFTVKYKDFEYRN"
     gene            87879..89036
                     /gene="alr"
                     /locus_tag="PC466_000328"
     CDS             87879..89036
                     /gene="alr"
                     /locus_tag="PC466_000328"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HDF2767764.1"
                     /translation="MQKITVPTWAEINLDNLRFNLNNIKNLLEEDIKICGVIKADAYG
                     HGAVEVAKLLEKEKVDYLAVARTAEGIELRQNGITLPILNLGYTPDEAFEDSIKNKIT
                     MTVYSLETAQKINEIAKSLGEKACVHVKIDSGMTRIGFQPNEESVQEIIELNKLEYID
                     LEGMFTHFATADEVSKEYTYKQANNYKFMSDKLDEAGVKIAIKHVSNSAAIMDCPDLR
                     LNMVRAGIILYGHYPSDDVFKDRLELRPAMKLKSKIGHIKQVEPGVGISYGLKYTTTG
                     KETIATVPIGYADGFTRIQKNPKVLIKGEVFDVVGRICMDQIMVRIDKDIDIKVGDEV
                     ILFGEGEVTAERIAKDLGTINYEVLCMISRRVDRVYMENNELVQINSYLLK"
     gene            89069..89356
                     /locus_tag="PC466_000329"
     CDS             89069..89356
                     /locus_tag="PC466_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribbon-helix-helix protein, CopG family"
                     /protein_id="HDF2767765.1"
                     /translation="MYDKSKEKIEVTLPDSLISEVDSIVQMENSNREDFAKAAFQFYI
                     TQKKKIHIKESMKTGYREMGQINLSLAELGMTVEEVSSDDKNEGKIAQGEY"
     gene            89325..89708
                     /locus_tag="PC466_000330"
     CDS             89325..89708
                     /locus_tag="PC466_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HDF2767766.1"
                     /translation="MKGRLPKVSTNCEIKRGDLYYADLSPVVGSEQGGVRPVLIIQND
                     VGNKYSPTVIVSAITSQINKAKLPTHVEISSNEYGLNKDSVILLEQIRTIDKKRLREK
                     IGCLDENMMIKVDDGLQISLGLFTF"
     gene            89879..90706
                     /locus_tag="PC466_000331"
     CDS             89879..90706
                     /locus_tag="PC466_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HDF2767767.1"
                     /translation="MRDHKGLNEIARIIRRDIVSMIHRAKSGHPGGSLSVVEILTALY
                     FDEMNVDSSNPKMEDRDRFVLSKGHAAPALYATLAEKGYFDKEELNGLRKIGRMLQGH
                     PDMKGTPGVEISTGSLGQGFSVACGMAMASKLDNAPWNVYTLLGDGEVQEGIVWEAAM
                     SAAHYKLDNLIAFLDNNGLQIDGDIESVMSLGSIVDKFKAFGWNVIEIDGHDFDQIFA
                     ALDIAKSTVKKPTMIVAKTIKGKGISFMENQAGWHGTAPSDEELEKALLELGGADNE"
     gene            90699..91640
                     /locus_tag="PC466_000332"
     CDS             90699..91640
                     /locus_tag="PC466_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HDF2767768.1"
                     /translation="MSKMATREAYGKALVKLGQINDNVVVLDADLSKSTKTHDFYKSF
                     PDRFFNMGIAEQNLIGAACGLSTAGKIPFASTFAMFATGRAFEIIRNSVCYPKLNVKI
                     CATHAGLTVGEDGASHESVEDIAIMRAIPNMTVLVPADGVETEKIIFEIAKYNGPVYV
                     RLGRSSVPVLFDEDYKFEIGKGTVLREGKDVSIIACGIMVNEALLAQEKLQEEGINAR
                     VINMSSIKPIDKDLILESAKETNAIVTVEEHSIIGGLGSAVSEVVGESCPTIVKKVGI
                     KDTFGESGTPNELLKKYELTCDDIIKTVKEAIIAKRM"
     gene            92063..93157
                     /locus_tag="PC466_000333"
     CDS             92063..93157
                     /locus_tag="PC466_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2767769.1"
                     /translation="MSEKVNVKTVISFAGAYVATVIGSGFATGQEIMQFFSFYGFAGI
                     IGGIISMVLFSWMGASVMSKGKELQLKEPIKIYRVYCGKYLGIFFEWFGPLFLFGVFV
                     VMISGAGATLTEYYGLNPFVGRVGMAVVALLTVSLGLDKLSKILGGIGPIIIIFTLLV
                     GGISLAKNIGNIGEAAQVLSTVKIAKPVPNAYLSGVIYTTYNTIVVMAFLTGLGASAA
                     NKKEAICGGILGGVALMAAAIMMHLAILSDIGNLYSKAIPSLFLADKISPVIGVLFSI
                     ILILGIYTTAVPLLWSVTNRFVDDKHPKFKLITLIAAILGLIGGFLPFDKLVGILYPY
                     TGYMGVIILVCVLYRQITKTSGYQEGISDK"
     gene            93383..93799
                     /locus_tag="PC466_000334"
     CDS             93383..93799
                     /locus_tag="PC466_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2767770.1"
                     /translation="MNVKFNIKGIIYGVIALVFVIGGFIFIPSMFVEKSKPIDYTVLQ
                     RNSIPEKILDVMDKYTNEERALAAKIDNKIYIIVTRGNNKYGIEMDKIESVVEEGKDV
                     LRVKIKYKDKEDSFPYIVVETNMSELPDRIELNATK"
     gene            complement(93981..94550)
                     /locus_tag="PC466_000335"
     CDS             complement(93981..94550)
                     /locus_tag="PC466_000335"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HDF2767771.1"
                     /translation="MKKEFRKKVIESRKNKSANFVLSNSNLITEKLLQMEDIRNATNI
                     MLYLNFNNEVQTDNLIKKLLSLKKIVSSPITIKENHTLIPTQITDLKEGLRIGAYGIR
                     EPNEKSPTIDIKALDVVIVPAVAYDIHCYRLGYGGGFYDRFLENLRKDAITIGIAFDF
                     QIFDSIPKETHDAQLDYIVTETRIITPNN"
     gene            94704..95861
                     /locus_tag="PC466_000336"
     CDS             94704..95861
                     /locus_tag="PC466_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S41 family peptidase"
                     /protein_id="HDF2767772.1"
                     /translation="MYLVISKKKAIFLGVILVIITAMVTSAFQLTLGNKVVISKELYE
                     DYKKYDKLLGLESIIKQDFYKKVSDTDLVNGAAKGLFLGTNDKYSGYYTKDEMENLIN
                     DSEGSYVGVGMYIGASKDGGLVVVPMKDSPAEKAGVKSGDKLVKVNGKSVSYKNSDEA
                     VRMMKGKKGKTVELTILREDKQLNFKVKTDQIIEKSIESKVIDNDLGYIEITQFISST
                     YTDFDKALKELKAKNIKGLVIDLRNNPGGMLDICKEVADELIGEGTIVYTKDNKGNTE
                     YLKSDKEKLGLPIVVLTNGESASAAEILTAAIVDNKEGISVGTTTFGKGLVQSVVRLK
                     DGTGYKLTTAQYFTPNGDYINEKGIKPTIEEKDENKQLDVATKWLREQIDK"
     gene            96048..>96636
                     /locus_tag="PC466_000337"
     CDS             96048..>96636
                     /locus_tag="PC466_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDF2767773.1"
                     /translation="MFNKNEILKKLIEEYDVKTTTDIQDMLKDLFASTIHQMLEAELD
                     DHLGYDRYDNKNKNTKNSRNRYRNKNVKSDFGEITLNIPRDRNGDFEPKVIRNYENDI
                     SGIENQVIGMYSKGMSTRDISSHLKSIYGIDISHSLIAKITDRVLPLAHEWQSRALDM
                     VYPIVFMGAIHYKVRSEGRIINKAAYIAIGVNLEGI"
BASE COUNT        38816 a        10392 c        17782 g        29646 t
ORIGIN      
        1 attttttgtc aaaaaaaaca aaaaatacgt atttattttt tcatttcggg aaaactaaac
       61 acaggaatta tggactttat aaaaatttaa ttcttgagga gtgatataag tgaaaaaagt
      121 tgctttaatt ttagctataa taggtgcgct taactggggt gcaattggta ttctaggtac
      181 agacttaata ggtagtatct ttggtggaac atatgaaatg gtaagtagaa taatatactt
      241 cattgtaggt ttagctggat tatacttaat accaagttta atgtctgatg atagagaata
      301 atttatgctt ttatgttaaa tacctcattc taaatgttta gaatgaggta tttaatttta
      361 taaaaatatt aatttgtttc ttttttaatg gtaaaataga taagaattga agttttaaaa
      421 agaagtatta tgtaaaaaag gagtactatt aatatatgtt tattattaat gaattaaata
      481 agattgtaaa tgaagaagta atatcttttc atatgcctgg tcataaaaag ggacaggttt
      541 ataaaaagtt aggatataaa gatatactaa aaaatttgta taaaatggat acaactgaga
      601 tattaggaac agataattta cactttccgg aaggaattat aaaaaattca caaaaaaaag
      661 catcaagagt atttaaaagt gattatactt gctatttagt aaatggtagt agctgtggaa
      721 tacaatctgc aataatgtca gtatgtagtc ctaaaagtaa aataataaca aatagagact
      781 gtcatcagtc tgttataaat ggatgtattt taggagatat agatatagag tatgtgcctt
      841 gtgagataag tgaagagaca aatgtcttaa aagggatatc tataagtaat gtgattgata
      901 taatagataa aaacttggat gcaaaagcag tactgcttac ttatcctaca tattatggaa
      961 tgacatatga tttagaatac atatgtaatt atgcacatag caaaaagatg gtagtgatag
     1021 tagatgaagc acatggtgcg catttagggc ttagtgagag gcttcctaaa acagctcttg
     1081 agcaaggtgc agatatagtt gtacagagta cacataaaac tcttccagca tttacacaat
     1141 cgtcaatgat acatatacag ggagaccgag ttgatataga taaaatattg aacatgttaa
     1201 gaattacaga atcttcaagc ccttcatatt tattattatc ttctctggaa ttagcagtag
     1261 atatatatga aaataaagga aaagaattaa tggaagagct tttaaataat attagaattt
     1321 tcaaagataa agttgattca aatattaata tatatgacac aaatgataaa acaaaaatat
     1381 ttatatcatc taaaaacatg ggtttaacag gttatgaact agaaaatatt ttgagaaaca
     1441 aatataacat acaagtggag ttatctaatt attatggagt tcttttaata tgtacaatag
     1501 gaaatactgc tgaggatttc tctagtttag aaacagcatt aaacaatgtt gtaaaggaag
     1561 actttaaatt tgaaaagtta gaaaataaaa aataccctgt tgttattcca aagaaaatat
     1621 taacacctag agaagcattt tataaaacta aaaaaagtgt taaaatatat gacagcatag
     1681 gtaaaatttg tggtgaatgt atagttccat acccacctgg aataagtgta atatctcctg
     1741 gtgaagtaat aagtaaagaa ataatagact atctaatgtt ttgtcattct aaaggcatga
     1801 ttgtgagtgg attgaaagat gtagatttaa attttataca agtaatagat ttagaagaca
     1861 tttaaaaatt atgatataaa agtagataga agtagatagt ttaaaattgt gaagagaaat
     1921 aaatagactg cttatataga gctatctaat aaaagtacta aaaaagtaaa aagtgtttgt
     1981 atggaggata tgaaaatgaa aggtaagtta ataattatag agagtggttc agatgcaagt
     2041 ggaaaggcta ctcagacaga aatattatat gaaagattaa aaaaagaagg ctatatgatt
     2101 aaaaaggtag aatatccaaa ttatgaatct ccatcatctg ccttagtgaa aatgtaccta
     2161 aaaggagact ttggtaaaaa tgcatcagat gtagacccat atatagcatc aacttttttt
     2221 acagctgata ggtatgcatc atttaaaacc gattgggagg agttttacaa tgaaggtgga
     2281 ataattatcg cagatagata tacaacctct aatatggtac atcaggcctc taaaatggat
     2341 atttgtgata gagaagagta tttaaattgg ttagctgatt atgaatttaa tttatttaag
     2401 ataccacaac ctgattgtgt tatattttta gatgtgccta ttgaatttag taaaaagctt
     2461 atggagaata gaaaaaataa aattacaggg gaagaaaaaa aggatattca tgaaagtgac
     2521 atagagtatt tagagaaatc ttacaacaat gctttatata tagcagataa atatgattgg
     2581 aaaaaaataa attgtgtttt agataacaaa ttaagaagta ttgaaagtat acataatgaa
     2641 atttataaaa tagttcttga ttcaataaaa cctatggaga gataaatatg tattttgaaa
     2701 atattatagg gcaagatttt gcaaagaaat atttaacaaa ttctataaag aaaaataaac
     2761 ttaataatgc gtatatgttt gaaggaatgg atggaatagg aaaaaagaaa tttgcagatg
     2821 aattatcaaa actattactt gattatgaaa atctcgaaaa tagtccagac tatgtactca
     2881 taaaaccaga tggaaatagt ataaaaatag ctcaaatcag aaatttacaa tcagatatag
     2941 taataagacc tcataaagac tataaaatat atataatcaa taatgctgaa aaaatgactg
     3001 tggaagctca aaatgcactt ttaaagacgc tagaggaacc tccaaactat gctataataa
     3061 tcttagtcac aaacaacaag gaatctttat tagaaactat aaaatctaga tgtgatataa
     3121 taaagttctc acctatacca attgaagact taaaacgtta tttgataaat acaggtatag
     3181 aagaagaaag agctcaatta ttggctattt tttcgagagg aagtattgag aatgctctaa
     3241 atctatctca gtcttctgag ttttcaatga tgagagaaga tatacaacag tatattcaga
     3301 taatgttaga taaaaacata gtggagattt taaatatacc aaacaatatg gaaaaatata
     3361 gaggtaagat tatagcttta ttagatatga tgataaacta ttttcgagat atcatcctat
     3421 taaaagaaaa tgtaaacaag aacatgttaa taaatgtaga taagctagtt ttcattcaaa
     3481 atatgagtgg aaaaattagt tattctcaat tgtccaagat tattgatata atagaagatg
     3541 caaagagtaa aataaaaagc aattgcaatt tcaatataag catacaagtt atgtctttaa
     3601 atatatacga ggtgattaaa tgataaagat agtaggtata aggtttaaaa gtgctgggaa
     3661 aatatattat tttgaccctg ttgattttaa tatagagcaa gatatggatg tagttgtaga
     3721 aactgcaaga ggcttggagt atgggaaagt agtcgttggt ccaaaagata tggatgaaag
     3781 cgaattagtt tctcctttga agccaattat aagaatagct acagaagaag ataaaaaagt
     3841 atatctagaa aataaggaaa aggcaaaaga aacttttgag ttgtgccaac aaaaaataaa
     3901 agaacatgag ttaacaatgt ttttaataga ttgtgagtat acgtttgata ggaataagtt
     3961 gattttttac tttacagcag aaggaagaat agattttaga gaattggtaa aagacttagc
     4021 tgctatattt aaaactagaa tagaacttag acaaataggt gtcagagatg aagctaaatc
     4081 tataggaggt ctagggcctt gtggtagaaa actttgttgt tcatcttggt taggtgattt
     4141 tcaaccagtt tcaataaaaa tggcaaaaga ccaaagtcta tctctaaatc caacaaaaat
     4201 atctggaata tgtgggagat tattctgttg cttaaaatat gagcatgatg tatatagtga
     4261 agcaatagaa aaaatgcctg ttgtaggtgc attggtgcaa tcagatgatg gaaaaggaaa
     4321 agttgtagaa gtgaatcctt tattagaaca aattaaagtg gaatttcaag acaagacagt
     4381 aaagatatac acaagagaag atataaaaat acttagagag cctaaaaaat gtgatggctg
     4441 tggtggtaaa tgtaaggata atgatggatt agatgaagcc acactaagag agctaaagaa
     4501 attagaagat taaatttaag gtagggcttt tcctaccttt tttaaagcaa ttaatgctta
     4561 aagttattaa tatttgagga gaatttatat atgcaattaa aagattcaga aagaatagat
     4621 gatttacaat taaaaggcct taaaattata caagatacta atggtttttg ttttggtata
     4681 gatgcagttt tattagccaa ttttactaaa ataaaaaaag atgccaaagt agtagatttg
     4741 ggtactggaa ctggaattat acctattttg atagctggaa aaagtgaagc taaaaaaatt
     4801 attggcgtgg aaatacaaga agatgtatat gaaatggcaa ctcgttctat aaaattaaat
     4861 ggattagaag aaagagttga gattataaat gaagatataa aatacataga caaagtctta
     4921 gacataaatg gttaccatgt agtcacatca aatcctccat atatgcatat tgatggaata
     4981 aaaaatccaa atgataaaaa agcaatatca agacatgaag taaggtgcaa tttggaagat
     5041 gtaattagag cttcatccag attggttatg cctagaggaa aattcttcat gatacataga
     5101 ccaacaagat tggttgatat aataacttta gggagaaaat ataaattaga accaaaggtt
     5161 attcaatttg tgcatccaag acctcaaaaa gcaccgaact tagttttggt tcaatttgta
     5221 aaagatggaa gaccagagct taaaatattg gacccattgt atgtttatgg agaagatggg
     5281 aattatacaa aagaattaaa agcaatatat aataataaag atataggaga gttgtaaatg
     5341 agtgggaaat tgtacatatg tccaacacca ataggaaacc tagaagatat aacatataga
     5401 actttaagaa cattaaaaga agtagacttg attgcagcag aagatacaag acatagtata
     5461 aaacttttaa atcattttga aatctcaaaa ccactaacta gttatcatga acataataag
     5521 gattcaaagg gagattattt gataaataaa ctaattgatg gtgaaaatat agctctgata
     5581 agtgatgcag gtatgcctgg tatatctgac ccaggagaag agataataaa acaagctata
     5641 caaaataaca tagagataga agtattgcca ggtgcaacag cctttgtaac ggctttagtt
     5701 ggctctggta tggacacaca tagatttgtt tttgagggct ttttagatag agataaaaaa
     5761 gttaggaaag cacaattgga agaattaaag gaagaaagta gaactataat tttctatgaa
     5821 tcaccacata gattgaagga tacactaaaa gatatgctta aaattcttgg taataggaat
     5881 atttctataa atagagaact tacaaaaaaa tatcaagaaa taataagaga aaatatagaa
     5941 actaccataa aaatatttga ggaaaaagaa gtaagaggag agtttgtatt aatagtagag
     6001 ggttttcatg gtgagaagtc aaagaaagaa aattatgatg ggcttacaga tagggaatat
     6061 gttttaaaac taattgaaag tggtatgaac aaaaaagatg caataaaaat agtttgtaaa
     6121 gatagaaagt taaagaaaga tgtggtttat aaacaagttt tagatttata aaacctgaat
     6181 ctgaggtgat tttatggaaa tagggaaaat tataatagag agtttaaaga gggaagatac
     6241 acataaaata tttatagaat tagataataa gcatgaatta gaaaaaataa ttcctaaaat
     6301 aagctgtatg aagtctgtag gtgaatgtaa atatcatgta gtaaattgtt ttgaacattc
     6361 tataaatgca ttaaaagaat tagaaatagt attaaatgat aaggattttt ttccaataca
     6421 tctaagaaaa catgtgtcaa actatttaaa cacatatatt gaagaaggaa taaataagtt
     6481 acatgtatta aagttgggaa catttttaca tgatataggt aagcctgata gtatgacctt
     6541 agatgaaacc ggaagagttc atttcacaaa tcatgaaaaa ataggtgctc aaataattga
     6601 caatatggga ataaagttag agttatcaac agagacatat agacttataa gtaaatatgt
     6661 aagatatcat atgatacttt tgtctctata taagaaaaat gatttgagta ggaaagaatt
     6721 aattaatgta tttaacttag tagatgagga cactataggt gtaataatgc ttgggtatgc
     6781 agatatagtg tctacagtaa aattattggg caagagtgga gaagtcagtg tgttaaagac
     6841 atatatggaa tatattttaa caaattactt gtataagagt aattatacac atgtataaat
     6901 ttagttaata taattgagtt ttagatgatt aattgaagtt tgaaatatac ggatttcaaa
     6961 aacataaaag aagttgtctt tgttgtaaaa ttatgaaaga caactttttt tatatcaaaa
     7021 attgaaattt tattaaggat acttaatggt ctattaatta ataaaccatt agtatttaat
     7081 ttatattaca atattgattt tgcttgtatt ggcgttgata gtataacaga ggtcttagta
     7141 gaaccaattt tctttatagt atcaatcaca ttttctagct cgtacatatc ttttacaatt
     7201 acttttaaaa gtaagcaatc atcacctgtt atatggtgac attctacaat cctagggtcc
     7261 tttgcagctg actcaataaa ttctgtatat ccattgcttg gaagagaaat atgaataaat
     7321 gcctttataa ctctgcctaa tgaatctggg ttgacaatag ctttatatcc ttctataaca
     7381 ccagactctt ctaatctttt gactctttct gaaactgcag gagaagttaa accaactatt
     7441 tttcctaagt ccttcataga aattctccca tcatcctgta aaatttctat gattctgtaa
     7501 tctgtaacat ccataaataa acagtccccc ttaaataaaa ataattaata ctataaaact
     7561 tttttagaat ctatcatttg tgtttttaaa taccaaagat ttctagataa atcaacctta
     7621 taaatgtgtg gttttgaaag tcttttgtat tgttcccaga tagtacttaa ttcatattgt
     7681 acatgatttt ttatttcaag aacagctttt ttattatatt tgcatctgcc ttttatatac
     7741 aatggtttaa gaagctcttt aactttgtaa tttgtaaata cctttgtttt ccatgtataa
     7801 gtaggatgga agatttctaa aggtttagac tcatctataa cttcatcatg taacataatc
     7861 aaatctgcct ctgccttatt gtcttcgtta tatattctta taactttctt gtaaccagga
     7921 ttatttattt tttctggatt ctcagaaatc tttatcttag gttcaagaac tcctttttca
     7981 caagatgcag ctaatttata aactcctcca agagaaggtg aatcgaaaga tgtaatgagc
     8041 tttgtaccta ctccccatga atttatagta gctccttctg ctttaagtga tgttatggta
     8101 tattcgtcta ggtcattaga tgcagtgatg ctgatatctg aaaagccagc gttatctaat
     8161 tgttttttag cttctttaga taaataagct aaatctccag agtcaagtct tatacccata
     8221 ggtttgtatc ctttttcaga aatatttttg aatactttta ttgcattagg aactccactg
     8281 tttaatacat cataagtatc tacaagtagt aggcatttat ctggataaac atcagcatat
     8341 gcttggaatg cttcaagttc attatcaaat ttttgtaccc aactgtgagc ttgtgtacca
     8401 attataggta tatcaaacat tttccctgct agtacgtttg cagttccagc acaaccacca
     8461 actacagcag ccctagctcc atatatccct gcatctggac cttgtgcacg acgtaatcca
     8521 aattcaaata cagggtctcc ttgagctgca aagcaaactc tagaggcttt agtagcaata
     8581 agagactgaa aattaactat tgttaacaat gctgtttcaa taagttgagc ttgatataaa
     8641 ggtgccttaa cagtaattaa tggctcatta gggaacatga tagttccttc ctcaacagca
     8701 tatatatctc ctgtgaattt aaattctttt aaaaatttta aaaacttgtc agaaaataaa
     8761 tttaagtttt ttaagtactc taaatcttca tctgaaaaat gaagattatc tatgtattca
     8821 acaacctgat caataccaca aactatagta taccctccat cacaagcgtt ttttctaaaa
     8881 aacatatcaa atacaacaat gtcttcatga atattctttt caaaatagcc atttaacata
     8941 gtaagctgat ataaatcagt aagaagtgtt agatttctca ttatttctct ccttaattat
     9001 tattaaatat taaaaattgt aaaaactccc acacttatac taaaacataa tatagtacaa
     9061 ctttcaagta taaagtatta cctaactatc ataaaattat ttaaagagga ggatgattat
     9121 aataggaaaa atatggtttt atatggtatc gataggaata ataggaagct tgatttctaa
     9181 aaatatgggt gaattaaata aagttatatt aagtgaaaca tcaaaaggta tagagtttgc
     9241 aataagtcta gctggtatca tggcactctg gatggggata atgaatatcg caaaagaatc
     9301 aggtttaatt gaaaagatag gtcaaaaact aaatcctata atgagaagat tatttccttc
     9361 tattccaaag ggtcataaag caatgtctta tatagttatg aatattgctt taaatatgtt
     9421 gggtgctgga aatggtgcaa cagcatttgg tttaaaagca atgagtgagc ttcaaacttt
     9481 gaataacaag aaagatacag ccactaatga tatgattatg tttatggtaa tcaatatatc
     9541 atctatacaa ataattccat ttactataat caaattaagg atggatatgg gggctcaaaa
     9601 tccaagtgaa ataattttta cgactttatt tgcaaccata atatctacag cagtagcaat
     9661 aataacatgt aaattttttc aaagaagata tagataaagg ggatgtagat acatggagat
     9721 attttcaaac ttacttatac caataataat tctgtacata gtagtttatg gtaaatataa
     9781 aaaaatagat gtgtatgata gttttgtaaa aggagcaatt gatggattaa aagcagcatg
     9841 ggatatccta ccatatataa taggtatatt tttggcaata ggaatattca aaactggtaa
     9901 aggtcttgat atgttagaat ggctatttac accaatagca aatatgatga gtataccaaa
     9961 agaattaata ggtctaataa gtgtaaaacc tttatctgga agtggtgctt tagggatgta
    10021 cagtgaactt gcaaatagag ttggaatagg aagtttagta gaaaaaatgg gtgctacgat
    10081 tgtaggttct tctgagacta ttttttacac aatggcaata tactatggaa gtctgaagat
    10141 aaaaaatact agacatacat tatcatgtgc tatgattagc catgttgcag gtgtcatagc
    10201 agctgttttt atttgctatg taatatttgt ataatttgtt gacaatatgg gaaaaatttt
    10261 ataatatagt gattatatag aaacaaatag taatacaaat tacaagctat gaaaagaaga
    10321 gtaaataaag gttttttcta tcagagagct aggttaggtg aaagctagtg tcaaaagctt
    10381 tattgaagat ggtcttggag ctttttatct gagcaagtgt gctagggtaa aacggttgga
    10441 cacgttatag tctactaagg tatctataaa atgtttctac atttcatgtg aaacataact
    10501 attatagatg aattagggtg gtaccgtgaa taatctcgcc cctatgttaa ctcataggag
    10561 gcgatttttt attatttaaa tgaaagaatc atatgattac gaacgataaa aaattaggag
    10621 gtaaataaca tgagcaaacc gagtttttat gtaacaacac caatatacta tccaagtgga
    10681 ggattacaca taggacatac ttattcaaca gtagctgcag atacaatagc tagattcaag
    10741 cgtttctgtg gatatgatgt aaagttctta acaggaacag atgagcatgg tgaaaaaatt
    10801 caaaagaaag ccatagaaca aggaatgtca gagatagagt atcttgatgg aatgataaaa
    10861 gatataaagg ccttatggaa tactatggat atatcttatg atgattttat aagaactaca
    10921 gaaaaaagac atacagacat aatacaaaag atatttacta aactatatga gcaaggtgat
    10981 atatataaag gtgaatatga aggtagatac tgtactcctt gtgagagttt ctggacagaa
    11041 tctcaattac tagaaggaaa taaatgccct gactgtggaa gagaaacata tttagtaaaa
    11101 gaagaatctt atttctttag attatctaaa tatgaagaca gattaaaaga gttatttaaa
    11161 gatgatagtt tctgttttcc tgctgctaga aaaaatgaaa tggtggcaaa ctttttagac
    11221 aaaggattag aagatttaag cgtaactaga acgacttttg actggggtat aaaagttcct
    11281 tttgatgaaa aacatgtaat ttatgtgtgg gtagatgctt tatgtaacta tataacagca
    11341 ttaggttata tgactgataa tgatgaagaa tttaaaaaat attggcctgc caatgttcaa
    11401 atagtaggta aagaaatagt gagattccat acaataatat ggccagcgct tttaatggct
    11461 ttaggtctag aagttccaaa acaagtattt ggacatggat ggatactatt tgctgatgat
    11521 aaaatgagta aatcaaaagg taatgtggtt tatccagaac ctataataga aagatatgga
    11581 atagacacac ttaagtactt cttattaaga gagtttgcat ttgggcaaga tggaagttat
    11641 actcatagaa attttgtaac gagaataaat tatgatttag caaatgattt aggaaactta
    11701 ataagtagaa ctgtagctat ggttgaaaaa tacaataatg gtataatacc aacagcaaaa
    11761 gtttcaactg attttgatgc tgacttaaaa gaacaagctg tttcaactag agaaaacttt
    11821 gaagctgaaa tggataaaat gcaattccat gaagcattag agagtgtatg gaaattagtt
    11881 agaagaacta acaaatatat agatgaaact atgccttggg cactagctaa agatgaaacg
    11941 aagaaagatg aattagacac agttttatat aatttatgtg aatctataag aataatcgca
    12001 acactaataa atcctataat gaatgagact gctaataaaa tatatgaaca tataggaata
    12061 aaaggtcaag atgatataac tacatgggaa agtacaaaaa catttggtct tattggagaa
    12121 aatgtaaaag tatttaaagg tgaaccttta ttcccaagat tagatgtaga aaaagagata
    12181 gaagaattaa ctaaaatgtt ctctgggaaa cctccagtag aagaaaaacc tttagagcat
    12241 aaagaagaaa ttactattga tgatttagac aaaatagagc ttagagtagg gaaaataata
    12301 agctgtgaaa aacatccaaa agcaaataaa ttattagtat cacaagttaa gattggacca
    12361 gaaacaagac aaatagtatc aggaatagct gaatactata agccagagga tttagtagga
    12421 aaagaggtta cagtggtatg taacttaaaa ccagttaaat taagaggtgt agaatctcaa
    12481 ggtatgatat tagcagcagg tgatgatgga gacccatatg ttttaccatt tacacaaggg
    12541 gctaaagatg gatgcgaggt tcgttagtag gtaattaaat agtaaggaga ttaaagatgt
    12601 tatttgactc acatgcacat ttaaatgatg aaagttttga tgaagataga gatgaactta
    12661 ttggttcatt aaaagataaa ggtgtagatt tggttgtaaa tccaggagca gatatagaga
    12721 cgtcgataac agcaattgaa cttgcgaaaa aatacgactt tatatattca gcagttgggg
    12781 tacatccaca tgatgtatca aaactagatg atacagcaat agaaactcta agaaaacttg
    12841 caactgagaa tgaaaaagtt gtagctattg gagagattgg attagattat tattatgatt
    12901 attctccaag agaagaacaa aaagagtggt ttaagaagca aattgaatta gctaatgagc
    12961 taaaacttcc aataataata catgatagag atgcacatgg agatactttt gagataataa
    13021 agaatactaa aaatcctgaa ataggatgtg tacttcattg ttatagtgga aatgtagagt
    13081 tagctagaga atatgttaag atgggttgtt atatatcaat tccaggcacg gttactttta
    13141 agaataataa aaaaactaga gaagtagtaa gagaaatacc tctagaaaga ttattcatag
    13201 agactgattc accatatatg tcaccagagc cacatagagg aaagagaaac aatccttctc
    13261 aagtatcttt tgttgctgat aagatagccc aggaaaaagg gatatgttat gaagaagtat
    13321 gtagagttac aaaagaaaat gcaaagaaat tttttaatat aaaatagaca aattaaatct
    13381 tataatgata tatataataa gtcattataa gtataggatg agagtgcctc aaaatgagtt
    13441 ttttagttca tgaggcactc tttttttatg aaatcaaata tattttcatc atttcaacaa
    13501 tgaaaaagaa gtttatcata ttttgagaca gtttgttttt atttgtttaa ttcatatttt
    13561 aaaatatatt ttcttaacat tgttaaaaaa gaatttacaa gatattcatt agaattaact
    13621 caactctaat attcacttaa cttaagtggt ttattatatt attaaagaga agtaaacgaa
    13681 aggtagatta aggaggctaa attttgtata cagttgatag tactaagata ttgataaata
    13741 tgaacttaga gaaactagaa aagatatact caatgataaa agatacatca agtatttcta
    13801 taattaaaga acctaacttg gctacagtaa tggtaagagc taatgaaagt gtaaaaaata
    13861 caacatttaa tttaggagag atattagtta ctgaatgtag tgtaaaggta gatgaaagct
    13921 tgggttacgg aatagtttca gaaaacaata ataagaaagc catttactta gcagttatag
    13981 atgcagtttt acatagcaat aacagtaaat ttgatgagtt aaagaattac ataaataaaa
    14041 gtgtatatga agagaactta aggtatgaac aagagattat tgatgaattt agcttgatta
    14101 ataaaacgaa agttcaattc aatgctatgg attaaatagg aggagaatca tggtaaatta
    14161 tacacaagaa atatatagaa agatgctaga tagtgcttcg tttcctggga aattaaataa
    14221 tatagataat ataaatatag aaaataatac aaaactattg aatggagcaa ttggtatagc
    14281 aatcacttta ttagaccaag aagttacctt ctatatagaa aattatactc aaaaagatat
    14341 aaaaaatata agagcgctta cagtgtcaaa tcaaatagat tatagaaaat cagattatat
    14401 atttttagat attaattcag aagtggatat attacagatt aaaataggtt cttttgaata
    14461 tcctgatgaa agtgcaacta tagtacatca agtaaatgat ttatcaacgt actctcaaac
    14521 taagtatata aagcttgatt tgagtggtcc tggtataaaa tctaaaaata gtatatatat
    14581 aaatggaatt agagaagaat ttatagaaag attatctacc ataaataaag attatccaat
    14641 aggaatagat ttgattttag tagataaaaa aggagaaatt gcatttatac caaggtcatc
    14701 aaaattaagt tgggaggtat tgtagaaatg gcttatgtag cagttaaagg tggagaagaa
    14761 gccatattac aggctaaaaa tatacttgag ttttataggg taaaaggaga tagcttgcct
    14821 atagatgtaa agcagattga ggaacaaatg tcttatgctg tagacaaagt aatgtctgaa
    14881 ggaagtttat acaacaagga actatcagca ttggctataa aacaagctca aggtgatata
    14941 ttagaagcct ctttctatgt aagagcttta aggtcaacaa tgcctagaat tacatattca
    15001 gaacccataa atacagaaga aatgagaata aaaagaagaa tatcagctac ttttaaagat
    15061 ataccaggag gtcagtatct tggggcaact agagactatg aaaatagaat attaaatgta
    15121 gaattattag aagaagatga aaaaaagaat agagatttta gagatagttt tataaatgaa
    15181 ttagaaacag tagatgaaat ccctgaattt acaaaaatat ctaatatatt tagaaaagaa
    15241 aatttattac aagaagaagt ttgtgaaaac aaattggaag aagttattga tgatattaca
    15301 agaaatagtt taagatttcc agtttctagg tcagcaaagt tacaggcatt gactagaggt
    15361 gaaagtggag tagtgtcagg ttttgcttat gctattgtaa gaggttttgg tgatgaacat
    15421 ccatatataa gtgaacttag aactggtaat gtatttataa aagtaaaaca tcccatctat
    15481 gaagatgaag aaataataat aggtgatatg ctggttactg aatgtgaaat agtttcaaaa
    15541 gcatcacaaa ataagactga aaattctaaa actaattcgg aagataaaaa taagatgtct
    15601 ttaggatatg gtctttgtat ggggaataat gagaataagg ctatatctat ggccatacta
    15661 gacaaatctt tggagccaaa tagtgaaaaa ctagcacaag atgaagaatt tgtattgctt
    15721 catatagatg gaatagattc attaggattt atatctcact ttaagcttcc tcactatgta
    15781 gattttaaag cggatgtaga aagaataaaa tagtttgtgg aggtaagttt aggtgatata
    15841 taactatggt tttttagacg aaaacacaaa aaaagaaata agaagaaaga tattaaaagc
    15901 aatatcaata cctggttatc aagttccctt tggttcaaga gagttgccta tagctaaggg
    15961 atggggtact ggaggtttac aattaacact atcattaatt ggtaaaaatg atgtagtaaa
    16021 agtaattgac caaggaagtg atgattctac aaatgcttgt aatataagga gctttattgc
    16081 aagtgtaagt aatgtagaaa ccacaaaaga tacattagaa gctacattga ttcaaacgag
    16141 acatagaata ccagaagaaa aacttaaatc taatcaaata ctaatatttc aagtaccaat
    16201 accagaaacc cttagaatag tagaacctag tgaagtagaa acaagaagaa tgcattcaga
    16261 agaagattat agtaggatgt gggtatatct ttatgaagat atagttagat ttaatgatat
    16321 atctatagca gttgaatatc catgtaaagt aaatgataga tatttaatga atccatcacc
    16381 tatacctaga tttgatataa aaaaattaaa tatgtcagac aatttattct tgtttggtgc
    16441 aggtagagaa aaaagaattt atgctattcc tccatataca aaggtagaac ctttagagtt
    16501 tgaggattat aagtttgaag aggaaaagtt tgaaggaaaa tactgtagtt tatgtaacag
    16561 tacaaataca tttttagatg aagtatatga cagtgacact aatgaaaagt actatagttg
    16621 ctcagataca agttattgtg aaaaagttag attaaaaaat aacagtatag atgtgacaat
    16681 aggaggtact tggaatgagt aaaataaatg tctctaaaag attagaaaat atagacaagc
    16741 aagtattaat aggaagaaat atcaatctta tttatggaga tgggtgtgaa aagtgttttg
    16801 aaagcacagg atatgaaagc aataatatat gtaagtattg tggttctata gttgcatgta
    16861 ataatgtaaa tttagaactt tatgaaggag aagtccttgg aattgtaggt gaatctggtt
    16921 caggaaaaag cactttatta aaaatactgt ttttccaaga acatgcaaat agtggagaag
    16981 tatatatatc ccattacaat aaagacacaa atatactaga gctttcagac caaaaaaaga
    17041 gatacataaa gaatcatttt atgggtattg tgtatcaaaa tccccacctt ggtttaaatt
    17101 tagactttag tagtggtggt aatatagcag aaaaattatt gatggcaaat ttatataatg
    17161 ttgaaaaaat aagagataga ggcaaagaac ttttaataaa aactaatata cctgtagaaa
    17221 gaatagatca taaaccaaaa tactttagtg ggggaatgca acaacgagtt caaatagcaa
    17281 aagctctttc aaataaccct ccaatattgc tattagatga ggttacaaca ggtttagatg
    17341 tttctgtgca agcggaagta ttggatttaa taagagaaat ccaaagagaa cttaagattt
    17401 ctatgatagt tgtatcccat gactttgatg ttataaagat gcttgctgat aggacaattg
    17461 taatgaaaaa tggaagtgtg attgagtctg gtcttacaga ccaaataatg gaggacccac
    17521 aacacccata tactcagcaa cttataaatt cattgctata aatatcgttt gtaaataagc
    17581 aaaatggggg tttttaataa aatgaaagaa actatacttg aagtaaataa ttttagtaaa
    17641 gactttgagt tacatgcatt gaacaagact ataacggcat gtagtaatat aagttttgaa
    17701 gtttcaaaag gtgagttttt aggaataata ggtaaatctg gagcaggtaa gtctaccata
    17761 ttaaaaagta tctataaaac atatatacca acaactggag aaataatttt taattcagaa
    17821 atatatggta atgtagacct ggctaaaatt ggagaccgag aaatgataaa tcttagaaag
    17881 aaagaaatag gatatgtatc acagttttta aagacacttc cacgaataac tgcaattgaa
    17941 ctggtagtac attctttaat tgagagtggg tttgaaaaag attgttcgta tgatatggca
    18001 aaagatatac ttaaccaatt tgaaataaag gaaaatttat gggatgcgta tccaaataat
    18061 ttttctggtg gagaaaaatt aagattaaat ttagctcaag ctatggttaa aaagcctaga
    18121 cttttgttac ttgatgaacc aactgcatca cttgataatc aatctaaaat atatgtaaaa
    18181 gaaaaaatgt tggaacttaa aagtcaagga actacaatga taggaatttt tcatgatata
    18241 gagtttatgg aaactgttat agataagacc tttactatgg caaaagggac tataagtgaa
    18301 agtggggtag cctagatgat aaaactaatt cataatgcaa atattgtatt agaagatatg
    18361 attttagaaa atggtcattt aatcatagag ggagatacaa taaaaaaagt atcaaatgat
    18421 aggattgatt acgcatttga ctttaatgag atagatgaaa taatagatgc aaaaaactta
    18481 tatgtaatac ctggtattat agatattcac agtgatgcca ttgaaaagga aatagagcca
    18541 agaccaagta cattattacc atttaatatg gcattttatg aactagataa aaaactacct
    18601 gcaaatggaa taactacagt ttatcattct atatctttag gggatggagt aggagttaga
    18661 agtattgata actctttaaa gatgattaaa aatattgatt catataaaaa tatagatagt
    18721 aagagtataa atcataaagt tcatttaaga tatgaagtgt tgtattatga aggtttagaa
    18781 aaggttttag aactattaga tgaaaataaa atagactact tatcaataat ggaccattct
    18841 ccaggacaag gtcagtatac aaatccaaca ttttataaag agtatgctac taaagtgtgg
    18901 ggagttacag aaaattatgt agatacatgg ttagatgatt tagtaaatct gcatgataat
    18961 ttagattgga ataaaatagc taatattata ggtatagcca aaactaaaaa tataaatgtt
    19021 gcatcacatg atgatgatac attagaaaaa atggatttca taaaaaatat aggcataaat
    19081 gtatctgaat ttcctataac tcttgaagtt gcaaaacatt caaaaaaatt gggtgttcta
    19141 acttgtttag gtgcaccgaa tattgtaaga ggtaaatctc ataataacaa tttaaaagca
    19201 atggatgcta tattggaaga ttgttgtgac attgtgtgtt cggattatct tccatcagct
    19261 atgataaagt ctatgtgtat agttgcagaa agaataaata atttaaataa agcagtcagt
    19321 ttatttacct caaatcctgc taaagcagtt ggtatatatg atgaaagagg tagtataaaa
    19381 gaaaataaaa aagcagattt agttttagta gatattgata gtgaatatcc aaaggtttta
    19441 aatactattg taaatggaaa aacagtttat aaaagggagg tataaaaatt gctaacagag
    19501 ttacattgtc atacaagtat atcagataat aattttacta ctgaagaaat aataaaaaaa
    19561 gcagcagaaa agaatataaa tatcttagca ataacaaatc atgacacatt atctggattg
    19621 gatgaagctc ttgtgcttgg agagcattat ggaataacaa taataccagg tatagaaatt
    19681 tcagcctatg attataaaaa tagaaaaaga gttcatattc ttggatataa catagattta
    19741 aacagtcaag aaataaaaaa tttgtgcaat ccaatggtat gtgacagaca taaagcatct
    19801 gttaagatgg taaataaaat tatagattta ggatacaaaa tatctttgga agatgtaaag
    19861 aaatattcat caaagactgg aatatttaaa caacatataa tgaaagctct tatagataaa
    19921 ggatatacag ataatatata ttcaagtcta tataaagaat tgtttcatag aggaaacggc
    19981 aaggtatatg tatctttaaa atatgtggat tacagagatg caataaaagc tataaaaaat
    20041 tctggtggaa tttgtgtgtt agctcacccg ggtcaaatgg ataattttag cgctattgaa
    20101 gagatggtaa aagtaggatt agatggaata gaagtatatc atccatctca caacaaagaa
    20161 ctagaaaaag agtcgctttc ttatgctaag aagtataatc tagtggtcac aggaggctca
    20221 gattaccacg gattttattc tcaacataat tatgaacttg gaagcaagag cttaaataaa
    20281 gaagatttat ttaagtttag gttagcttta ggaggggtat tataaatgtc ttttttacaa
    20341 gtaaaaaatg taggtaaaag ttatggacaa gttaaggtgt taaaagacat atctattgat
    20401 attgaaaaag gagagtttat ttgtttacta ggtccaagtg gttgtggaaa aagtacactg
    20461 cttagaataa ttgcagggct tgaggataaa catggtggaa aaataataat aaatgataag
    20521 gatatgacta attcaccacc tgaaagtaga aattttggta tagtttttca atcatatgca
    20581 ttatttccaa atatgaatgt ttacaaaaac atagcctttg gactagaaaa taaaaacata
    20641 agtaaatcta atattgataa aaaagttaaa gaagttctag acgttgtaga attaagtgga
    20701 tatgagaaaa aatatccatc acaattatca ggtggacaac aacaaagggt tgcattagct
    20761 cgtgcgattg ctttagagcc agacttttta cttcttgatg aacctttatc tgcattagat
    20821 gcaaaagtaa gacttaaact tagggagcag attagaagtt tacatagaaa actaggcatt
    20881 acaactataa tggtaacgca tgaccaagaa gaagctcttt gtttagctga taagatggtt
    20941 gttatgaata gaggagaaat aatacaagtt ggaacgccaa aggaggtata taaaaatcca
    21001 gaaacacctt ttgtagctga ttttatagga acaataaatt ttatagatga tggtattaat
    21061 aagatagcta ttagaccaga agatataaaa gtagagtcta atagagattc taaagataag
    21121 gatataaaag tgggagaaat tttagatatc gaatttagag gatttaacta tagaattaca
    21181 gttgagtatc gttctaagca aatgaaatta gatgtagttt ccaaagttgc agaacaaatg
    21241 aaactgtgca taggttctaa aataaacttt aagataccta aagaaggaat tgtacaatat
    21301 aaatcagagg gatgtgctta atagctaggg gtgaataaat gataacatca aaaaataaaa
    21361 gaagaataag tgatagcaca atacaaaaat atttcttgat tttttcggta attgtactaa
    21421 tagtatttat attatttcca ttagtatcat tattaaaaaa tgcatttatg gatacaagtg
    21481 gaaattttat aggaatttca aactttagta aatatgttga aaatccaagt cttatagcat
    21541 catttaaaaa ttcaattttt gtatctacag tctcatcttt aatatcacta tgtttagcat
    21601 ttatatattc atacgcaata acaagaacaa atataaagtt taaagatttt tttaaaacta
    21661 tgggaatgtt tccacttttt gcaccaacta tgttatatgg tatttcactt atataccttt
    21721 ttggaaataa gggaatcttt acaaccatgg gtctggaagt accactatat ggtccattag
    21781 gaataattat ttctcagatt ctatttacat ttccacaagc ttttttaata ttatctgtag
    21841 cactttcgat ggctgattat agactttatg aagcagcaga tagcttgggt gctagtgaat
    21901 ttaagaaatt ttgcaaaata acaattcctg gtataaagta ctcattactt agttcattct
    21961 ttgtatcctt tatacttgca tttacagatt ttggagcagc taaggtagtc ggaggaaact
    22021 acaatgtact ggctactgac atatataaac aagtagttgg acaatttaac ataccaatgg
    22081 gagctactgt ttctatggta atgttaattc ctgtactaat agcatttaca ttagataaga
    22141 tggcaagtaa gaaacaaggt atgaccataa ctgcaaagtc tatgccatat aagattaagg
    22201 aaaataagtt tagagataga gtatttttaa tagtatgtag ttttataaca ttgctaattt
    22261 ttattttaat attcgtttca gttataggtt cagttataaa gttatggcca tataatttaa
    22321 gctttacaat ggaacactat acatttaaag gtattttggg aagtggaata aaaacatact
    22381 taagcagttt gaaaatatca actttaacag caatatttgg aactatattt gtatttttta
    22441 gtgcttatat aatagaaaag gtggataagt ttcctaaatt aagacaaaca gcttaccttt
    22501 tatcaatgat accaatggcc ttacctggct tagttttagg tatatcatat ataacttttt
    22561 ttaactcagc aagtaatcca ttaaattttt tatatggaag tacagcaata ttagttatag
    22621 taaatgtagt tcatttttat tcagtttgtt ttataacctc aaattcatct ttaaaaatgt
    22681 tggataaaga gtatgaatta gttgcaaaat ctataaatat tccattctat aaagtatttt
    22741 ttaatataac agttccgatg tctataacat caatacttga aatagtagta tattattttg
    22801 taaattcaat ggttactgtt tcagcattaa tatttttata tatacctcaa actcagactg
    22861 catcaatatc aatactaaag ttagatgaga taggatatat aggaccatca gctgctatgg
    22921 cagtattagt gctattaaca aatataatag taagactttt gtacgaattt gtaacaaaga
    22981 aattaaaaaa taacacacaa aaatggcagc aaaaagatgt tgcatagggg aggaaaaaat
    23041 gaaatttaaa aagctagttt ctttaggagt attatcaaca cttttattaa gtgtaataac
    23101 aggatgtagt actgattcat caggttcaga ttcaaagtct gatagtaaga caaaagggga
    23161 tttaacagtt tacacagcaa ttgaagaaga tagtatagag ccatatttag ctacatttaa
    23221 agagaaatat ccagatatta aattaaatat tgttagggca tcaacaggag atataacagc
    23281 aagattatta gcagaaaagg ataatcctca agcagatgtt gtatggggag ttgcagccac
    23341 aagcttattg gttgcagatg accaggggat gttagaacca tatgctccaa aaggttctga
    23401 agaaatagag tctgcattta aagatgataa agaagttcct tcttgggttg ggatagatgc
    23461 ttggatgaca ggtataacag taaacactaa agaattaagt gataagaaca tcccagttcc
    23521 tagttcttac gaagatttaa taaagccaga atataaaggt cttatatcta tgcctaatcc
    23581 atcttcttct ggtacagggt acttaacagt atcagccctt atacaaatta tgggggaaga
    23641 aaaagcatgg cagtatatgg ataagttgca tgagaatatt ggtgtataca ctcaatctgg
    23701 ttcagctcca gctacatcag cagcttcagg agaatatcct attggtatat cttttggata
    23761 tagaggtata aaattaaaag aggaaggcta tccagtagaa gtagtatttc caaaagaagg
    23821 ttctggatgg gatatagaag caaatgctct tgtgaaaaaa gataatataa aagaagcatc
    23881 aaaagtattt ttagattggg ctataagtaa agatgcaatg aatgaatact ctaagaacta
    23941 tgcagttact actatttcta caggaaatcc aataccagaa ggattcccta aaaagccatt
    24001 agagcaaatg atagataatg atttaaaatc agcagcaaaa aatagagaag atatactaaa
    24061 taaatggata tcaaaatatg atggtaagac agaaaaagag agttaagtaa aactatacaa
    24121 atggagtaaa aagaaaaaat ttttttaagt agattttatt ataataatat aagttgagaa
    24181 taatataggt caagaaaagt gaatattcta taaaaatgta tagagtaagt ataccattca
    24241 gtttgaatgg tatatttttt atttttagag attaatttag aaatagatat actacagttt
    24301 aaaatagtat attttaattt cattattaaa gtatagatgt tatatataaa gtaaataaga
    24361 tattaaataa ttataaacta aagtaaataa aatattgagc gattattaaa aagatatata
    24421 tatatatttt aatttgagca gtttgttata tattataaaa aaagagaaaa ataaaaggta
    24481 aattgtttct ggataactta aaattggaag taagaatatt taactagaga agaattattt
    24541 aagttcaggt tagctctagg agtagctgat tttataggag caatagattt tatggatgat
    24601 gatataaaca tgatagcaat tagaccagaa gatataaggg tagaatttaa tagagatttc
    24661 aaagaaatta tagacctcaa actcagaccg tatcgatata aaaactaaag ctagatgata
    24721 tagtgttgta tataggacca tcagctgtta tggaagtatt agtgctttta acaaatataa
    24781 tagtaaaact tttgtatgaa ttgataataa aaaaattaaa aaccaagaca taaaaatggc
    24841 aacaaaaaga agttgaataa gggaggtaaa aatgaaattt aagaagttag tctctttggg
    24901 aatattatca acacttttat tgagtgtaat aactggatgt agtaatgttt catcaggttc
    24961 aaacttaaag tctaataata agacaaaagg agagttaaca gtttatacag caattgagga
    25021 agatagtata gatacatact tagctacatt taaagagaaa tatccagata ttaaattgaa
    25081 tgtacttaga ttatcagtag gaggtataac agcaagatta ttagcagaaa aagataatcc
    25141 taaagcagat gtgttatggg gtgttgcagc tacaagtttg ataattttag atgacaaaga
    25201 aatgctagag ccatacgctc cgaaaggctt tgataaggta aatcctgcat ttaaagatga
    25261 taagaaagtt ccttcttggg ttggaataga tgcttggatg actggtataa cagtaaatac
    25321 taaagaatta aaagctaaaa acatatcagc tcctaattct tatgaagatt taataaagcc
    25381 agaatataaa gatcttatat ctatgcctag tccagcttct tcaggaacag gatatttaac
    25441 agtatcagaa ctcatacaaa ttatgggtga agaaaaagca tggcagtata tggataaatt
    25501 gcataaaaat attggtgtat acactcagtc tggttcagcg ccagctatat tagcagcttc
    25561 aggagaatat cccattggta tatcttttgg aaatagaggt ataaagttaa aaggtgaagg
    25621 ttatccagta gaagtagtat ttccaaaaga aggttctgga tgggagatag aatcaaatgc
    25681 acttgtgaaa aaagataata taaaagaagc atcaaaagta tttttagatt gggctataag
    25741 taaagatgca atgaatgagt attctaagaa ttttgcagtt actacaattg acacgggaaa
    25801 tccggtgcca gaaggatttc caaagaatcc attagaacag atgatagata atgatttaaa
    25861 atcagcagca agaaatagag aggctatact aaataaatgg atagaaaaat atgatggaaa
    25921 gacagaaaaa gagagctaag ccttacaata aaatttagta caaaaagcgc ctagaatata
    25981 agttttacat ctaggctctt ttgatatatt tatttaaaat gcatatttct atataaaaat
    26041 aaatagttta gtaccttgat taaattaaat aaaaacctta aaataaagag atgtaaagaa
    26101 aaactaaaaa cgaataaaag gtgaatttat atgataaaag aaataatagt agtagagggt
    26161 agagatgacg ttacagcagt taagagagca atagatgcag aacttataac tacaggtgga
    26221 tttggatttc caaaaggtgt aatgcagcgt ataaaagctg ctaatgaaag acgtggtgtt
    26281 ataatattta cagacccaga ttttgcaggt gaaaaaataa gaaaaaaaat agcatcagaa
    26341 gttccaggat gtaaacatgc atttctacca agagaggaag ctaaaaagga tggagatata
    26401 ggtattgaga atgctactcc tcaaagtata atagcagctc tgaataaagt tagaactgaa
    26461 aatacagaaa aaagagatga atttaagcaa gttgacttaa ttagaaatgg tcttataggt
    26521 aatgaagaag catcacttag aagagatgca cttggaaaaa tacttggaat tggatatgga
    26581 aatgcaaaac aatttttaaa tagattgaat aattatggag ttgaaagaga agaatttata
    26641 gatgcattaa aacaaatcta aacgtaatgt ttaatgtatg aaaaatatgt atataaaata
    26701 aattgtggaa ttacggttaa tttaagataa attatttata atatatacct tattttaaat
    26761 caatgtaaat acatataaat aagtataatt aataaaatta aatatcaaaa taagttaaaa
    26821 aggagtaaat aatggataga ctatcttcac ataatgcaac aaaggaagta gtacaaaaat
    26881 ataattttaa attttcaaag tctttaggtc aaaatttctt gatagatagt aatataattg
    26941 ataaaatctt atctggagct agaatcacaa gaggagataa tatcatagaa gtaggacctg
    27001 gtataggaac tcttactcgt gagatgggta aaatagcaga aaaagtagtg gctatagaaa
    27061 tcgatagaaa tttaattcct atattgaaag ataccttgtc agatttagat aatacagagg
    27121 ttgtaaatca agatatacta aaagtagaca tacaggaatt agtaaaagat aaattaaatg
    27181 gtggaccagt taagcttgta gcaaatcttc catattatat aactactcca atagttatga
    27241 aatttttaga ggaagacata cctgtaacag acatagtagt catggttcaa aaagaagttg
    27301 cagatagaat gaatgctatt ccgggtacta aagattatgg ggcattatct atagctgttc
    27361 aatactattg tgatacagag attgtggcaa aagctccaag acatatgttt ataccacaac
    27421 caaatgtaga ttccacagtt ataggtttac atgtaagaga taaaagaaaa tatgatgttc
    27481 ataatgaaga catatttttt aaaacagtaa aagcatcctt tggacaaaga agaaaaactc
    27541 ttcttaattc gttgggaggt cttggttttc ttaataaaga tgaaataaga gaaatattaa
    27601 aagaagctaa tatagacgaa aaaagaaggg gtgaaactct tagtatagaa gagttttcag
    27661 ttctttcaaa tataataaat acaaaagtat cttctaaata gaaggtactt tttttaattt
    27721 tgttaacata tattgtttag agaaactgtg ttaagggggg attgcagtgg gttctaaaag
    27781 aaagtttaaa agagactata taatactaga agctaaagac ataaacttta gatacaaaga
    27841 acgagtactg ccaaaagctt ttgcaaaagt tgaagtaaat gatgaaaaag caattattgc
    27901 attatatgta gaaaatctaa aatatgttaa agatgggtat aaagcagtag caataaaaga
    27961 tgaccatgga ttaatagact taggaaatat aattttaaat gaacaaggaa gaggtgaatt
    28021 tgttttagat ttagaagatt ctgatgatga gataaaaggt attgcattat tgtatgaaag
    28081 aaatatacct ttaattggat ttaagggaaa taagcttgaa aattatgagg acatattatt
    28141 tcaagaggta gaggaagaag aatatgaaga atatgaagaa tatgaagagt tggaagaaga
    28201 cgaagagata gaggataatg aggaaagtga tagagacgaa gatagtgaag aagaatatat
    28261 tatagaagaa tatgatgaag atgagtatga agactattgg gaagatgatg aagatattga
    28321 agaaggagag ttaaaagcaa gaacggaagt agaagattct ggtgatgagg aaatagaaga
    28381 gttcaataat tataaggaaa tagaaaatta taatagggtt aaagtacagg aagaatatat
    28441 agacatagaa tatgatgagg aagaagagga agaagaagaa gtttttgaag taaatagaga
    28501 agaagatagg tttgtttcct caaaacctac taaatcaaag aaagttcaaa aagatcagaa
    28561 taatattgaa aaaataaaaa gagctaatgg agtaagtcaa ggagagagtg gaaataaaca
    28621 aaccagtaca ttacttatgc caagacaaat aaaaaaaggt ttgaaattat ttaaagaagt
    28681 aaaacctttt gtaacagatt atatagataa gacaagatgg tggaaaatag agataaatcc
    28741 tacaacactg tgtggatata caatgcctta tttaggatat ttaaacgtat tgaattacac
    28801 tatgtatagt gatgcagttt tacattcata taaatacaga cactatttat ttggtgttca
    28861 gtatgatgaa tataataaga gaaaacatta tatttatgct atcccaggaa atagaaatga
    28921 acagccagac aatggaagca caggattttt aagatatcaa gcttgtgata atagaacaaa
    28981 tagtttagga tattggctat gttttataga ttctagacaa agaaatatag ttaggtaaaa
    29041 ataataaaaa tgaaaaaatt tagactcaat tcttatttta ctgaaaaaat taatgaaatg
    29101 tagtacaaaa ctttaaaaac tattgataat atttaaatat tacactacaa tatatcttga
    29161 aatacctatt atattatgga ggaaaattat gataaacgag caaagaattt taaatgagtt
    29221 tcttgaatta gtacagatag atagtttatc tttaaaagag gggaatgttg ctaaagtatt
    29281 agttaaaaaa ttagaagaaa taggttgttc agtagtaata gacaatgctg gtgaaaaagc
    29341 aaatggagaa actggtaata taatagctac attaaaagga aataaagaag gaaagaaaat
    29401 attatttagt tcacatatgg atacagtaac tccaggtata ggggtaaaac ctatagtgga
    29461 tgaagcaaat ggaataataa aaagtgatgg tactacaata ttaggttctg atgataaagc
    29521 aggtatagca gctatattag aaggcttaag atatataaat gaaaataaca tagaacatac
    29581 tgatatacaa gttgtattct ctatatgtga ggaatgtgga ttagttggag ctaaaaattt
    29641 agactatgga aaaatagatt ctgaatatgc atttatatta gatagtggtg gttctccagg
    29701 tgaaataata gtaaaagctc ctgcacaaga tgtaataaat gttaagatat taggaaagac
    29761 tgctcatgca ggtcttgaac ctgaagctgg aataagtgct ataatggtag ctgccagagc
    29821 aatagaaaat atgaatttac ttagaataga cgaagaaaca actgctaaca taggaattat
    29881 aaacggtgga acagctacaa atatagtaac aggagaagtt aatatagttg cagaagccag
    29941 aagtctaaaa gaaaataaat tagatgttca aactaaacac atggtagaga cttttgaaaa
    30001 agctgcaaaa gattttggag ctcaaattga gatagatgtc aatagagcat atacaccaat
    30061 agatgttagt gaggattctg aaataataaa acttgcaaag aaggcttttt caaacttagg
    30121 tatagaaggt catactgaat ctacaggagg aggtagcgat acaaatatat taagtaagaa
    30181 tggtatcgaa gctataactt taggaattgg tatgaaaaat gctcatacac taagtgaaca
    30241 tatagctata aaagacttat atgactctgc taaaatggta gtggagataa taaaggaagc
    30301 ataaatttaa ataatagtgt ataatatata tatcgcctag cttaagctag gtgatttttc
    30361 attttataga agattgataa tctctattga aagcaaagag tatacatttg catataagag
    30421 agtgtttaat ttatgttcag atgtaggttc ttaataatat ttagattgtt tcataaggga
    30481 ggaataaata tggaaacaag gtatgaagaa gcaaataaaa taacaataca atcaatactt
    30541 tggaatgtag tattaacaat aattaaggtt atagctggtg ttattggtaa ttctagcgct
    30601 atgattgcag atggattaca ttcagcatca gatattataa gttctatagg agtactaata
    30661 ggcaattatg tatcttctag acctggagat agagagcaca attatggtca tgagaaagca
    30721 gagacattag tatcatttgt gttatcaata ttgcttattt tcgtttctat aacaataggt
    30781 atagaggcaa ttaaatcttt atttaactta gatgcattaa gtgttccatc aatattacca
    30841 ttagtagtat cagttatttc aatcctgata aaagagtatc aatatagaat aacaataaaa
    30901 gttgctaaaa agataaattc accagcctta aaagctgatg cttggcatca taggtcagat
    30961 gctttatctt cagtagctgc ttttataggt ataggtggtt ctattttagg gtttaagcca
    31021 ctagacccaa ttgcgtcaat tgtagtggct atatttgtag ctaaagtagg aattagtata
    31081 cttataagtt ctgttaatga attgatggat gtttcagttg acgaagaaga gataaaagaa
    31141 ttaaaattta ttgtagcaga tacagaaggt gttaaaaatc ttggtgatat aaagactaga
    31201 aaacatggag ctatggcata tgtagatttg actatatgtg tggatgaaaa tttgacagtt
    31261 aagcaaggtc atgatattgc taccaagctt gaaaaacata taataaaaca tatggaattt
    31321 gtaaaaggca taacagttca cgttgaacca tgtactaatt gccaaggaaa taagtgtaat
    31381 aattaattaa aacttaaaaa aaagtgtaaa aagttatata attgttttat gattataaac
    31441 tctaggggtg gttaaatgag caagaaaaga aaactaaaga aaaaagctgc aatattaata
    31501 ggagtagttg ttttctttat aatatacttt atatccttta gaataggaat aaatatggaa
    31561 aaggataaaa gtgaagtgcc aaagaaggta gaaaaagaag aagaagataa taggtcttta
    31621 aggactcaaa taaaagaaaa gaaaaaggtt tatatatcag acaaaaatat agaaaacata
    31681 aaaattgaag aagatatgtg ggatgaaata aagttatttt tctcagattt taagaaagta
    31741 agaaatacta cttcttctta cgaagcagtt tatgaaggtt attctgatga tggagttaaa
    31801 ttttctactg accttaactt ttttagagta tatactgtaa ataaagaaga atattataaa
    31861 gtaccagtta gttctaagga tgcttttaag aaacttttag atgagagtat atatacttca
    31921 tttgaccttt taagtcatta taaagattgg aaagaggtta ctataactca tggaaaagaa
    31981 attaaaaaag ttcatagatg gaaatttgat gatttagcac ataagatgat ttcaaagagg
    32041 gttgtaggaa aagttcaacc tgagaaaagt aaggaaagaa gtgactataa ttttactata
    32101 aatataaaag gtgataattt tgatgtaaaa gttgatacaa tgggaaaaga ttatgtaaaa
    32161 gttacttcta agaaaaatgt atcttactat gaggttcata caagtttatt tgattacctt
    32221 aaaaatgaga tatttgaaat tggaaagaaa taagacttta agaaggctat caaattagat
    32281 atttgatagc ctaaattatt tttatatatt atttttcaac caacaagtct gcaaccttat
    32341 aaattggacc agcaccagca gttattacta aatcattatc cttaacattt tcacgtaagt
    32401 attttactat atcttcaaat tcttttatat agatggcatc tacattgttt tgatataatt
    32461 tctcaaccaa gtccttagaa tgtatatctc cagggtcttt ttccctagca gcatatatat
    32521 ctgttatgat aactttatca gcagcataga atgcctctga aaattcacct aaaagagatt
    32581 ttgttctagt ataagtatgt ggctggaaga tacaccataa agttgatttt tttaattttt
    32641 tggcagcagc taaagttgct tttaactcag ttggatgatg tgcataatca tctactacta
    32701 aagcattctt ataataccct ttagtttcaa atcttcttcc gacaccttta taaattttta
    32761 tattttttct tatagtctct aagtcaatac cagaaacaag agctgccatt atagcagaag
    32821 aagcattgta tatgttatga agaccatata cagaaagttc aaattctcct aaatctcttc
    32881 cttcatattc tattctaaat attccatgac cactattgtc aaagtgaata tcttttatta
    32941 cagcatcatt gtcagaatct ctaccgtatt ttataatagt agctttaaca tcatacaata
    33001 tgtcatcaat attttcatca tcgccattta ttatgaaata gccttctggg ggtaataatt
    33061 ttccaaattt gttaaaagaa gccttgattt catctattcc agagaaataa tcaagatggt
    33121 cttcttcaac atttaaaact atagatatct ttgggttaaa attaaggaaa ctatctacat
    33181 attcacatgc ttcagttata aagtggttgg aattacctat cttaacatta ccacctatca
    33241 tacttaagtt accaccaact agtatagttg ggtctaagtc tgcatattca aagattgtag
    33301 ataacataga tgttgtagaa gtttttccat gtgttccaga aactgctata gaatttttat
    33361 attccctcat gatttggcct aaaaaagtcg ctctgttcat taccaattta tttttttctt
    33421 tagcagccac aagttcttca ttgtctggat gaactgctgc tgtataaaca accatattta
    33481 catcatctga tatattatct tttttctgac caatataaat agttgcccct tggtccctaa
    33541 gtttgtctaa taggtatgat tcgtttgaat ccgaacctga aacttgataa cctttattga
    33601 tacatatttc agctaatgca ctcatgctga taccgccaat tcctataaag tgtatattca
    33661 taataaaacc acctttcttt ttaattaagt cctacaatat gaactattta tgtggtataa
    33721 taatataatg ttcaatattt tataattaat atgcatataa tattatatgt attttatttt
    33781 tgaatataat aaaacataag taatattata ccacaataag aattgttatg cattagttag
    33841 tttaacgtta tataaaggta cttgtaggag gaaataataa tgaaatttaa aagaacagag
    33901 agaattggag caatagttaa aatactgtct gataatccaa ataaaatata tacattaagt
    33961 tattttacaa atcaatttaa tgcagcaaaa tcaacaataa gtgaagattt attagttgta
    34021 aaaaatgtat ttgagaagct acatttaggt aaagttataa ctatctcagg agcagcagga
    34081 ggagtaaaat atatacctaa aacttctata gcagaaaatg cagagttctt aatggaatta
    34141 tgtgagagaa tatgtgacaa gtctagaata ctatctggtg gttttttata cttgattgac
    34201 ctaatttatg accctacaat agctgctaag ataggaaaga tattcgcatc aaatattgag
    34261 tatgtagatg cagattatgt tgtgacaatg gaaacaaaag gtatacctat ggcacttatg
    34321 actgcaaaag ctatgaattt acctctagtt ataataagaa aagatataaa ggtatcagaa
    34381 ggtcctacac ttagcatgac atatgtgagt ggaaacagct ctaaagttga aagtatgagt
    34441 ttgccaagaa aagctcttaa accagatagt aaagttataa ttatagatga tttcatgagg
    34501 ggtggaggta ctataaaagg aatggtagac cttatgaatg aatttggtgc agaggttata
    34561 ggtactggag tattcatatc tacaacgaat ccttcagaaa aaatggtaaa agattatatt
    34621 tcattgattc aattggatgt taatggagat aaaatagtag tagaaccaaa cttaaagact
    34681 tttaaagatg aatatagaaa tgaagattta gacgaagaag aagattcaga atttgaattt
    34741 gagatagatg aagattaata aaaaaaatat ttagaaaaat atgtaaaaat aaaaagagga
    34801 tatccctagt tgttcataga attatttaaa aaacagttta tattaattta ttccagcgat
    34861 aataatttta atataaatta atttctgtca aaatcaaagg gggatatttt ggtatgaaga
    34921 taactgacgt aagagtaaga aaattaacag aagaaggtaa gatgaaatgt atagtttcaa
    34981 taactttcga taatttgttt gtagtgcatg atataaaagt tatagaaggc cataatgggc
    35041 tatttatagc aatgcctagc agaaaagtag gcgaaggaaa tttcagagat atagctcatc
    35101 caataaatgc agaaatgaga caagttttag aagatgcagt tttacaagca tatcatgaag
    35161 cattagttca atgggaagta gctgctgaat aataaatata taaaatggag agagcccgaa
    35221 catttaggct ctttttaaat gtagaatttc tattaaaata tgtacttttt agtaaaaaag
    35281 tgctatatta ttagtgataa tgtatatgtt gtatacaaat tgttagataa atgtattata
    35341 atgtatattg attaagagaa taatacgaat aaaattaaat tagattgaat ggagtgtatc
    35401 aatgaacttt aaagctataa tccttgctgc tggcaaagga acaagaatga agtctaaata
    35461 cccaaaagtt atacataaag tatgtggaaa agaaatggtt aaccatatta tagatgtttc
    35521 aaaaaaatca ggggtaaaag atactgtcgt gattttagga catgaagctg aggtagttaa
    35581 agaaaagctt gcagaagaaa ttataatagc catgcaaaca gaacaacttg ggacaggaca
    35641 tgctgtaaag atggctaaag aatatattaa tgatgaagat acaatagttg tactttgtgg
    35701 agatactcca cttataaaag aagagacact gaagagatta tttgaatatc atatagaaaa
    35761 taaatatcat gctacagttc ttacaacaag agttggaaat ccaacaggtt atggtagaat
    35821 aataagagat aagaagggtg accttcttaa aatagtggaa caaaaagatg caaattcaga
    35881 agaaaagatg ataagtgaga taaactctgg aatttattgt tttaatggaa agagtcttag
    35941 agaagcacta gatttgctaa ataataacaa ttcacaaggt gaatattatt taactgatac
    36001 tgctaaaata atgagagata aaggattaaa agttggtgca tttgcaggtt caactattga
    36061 agaacttatg ggcgttaatt caagagtaga attatcaaag gcagaagaaa ttatgagacg
    36121 aagaataaat gaatctcata tggtaaatgg agtaactata atagacacta actctaccta
    36181 tatagaatct gatgttatga taggcaatga tactataata tatccaggtg ttatgttaca
    36241 agggaaaaca aggataggtt cagattgtat aattggaatg aactcatcta taacaaattc
    36301 agaaataggt gatggtacag aaataaaaaa ttcaactata attgatagta aggttggaga
    36361 aaattctaat gttgggccat atgcatactt aagaccaaag agtgacttag gaaataatgt
    36421 aaaaataggc gattttgtag aagtaaaaaa tgctattata gaagatggat caaaagcatc
    36481 tcacctttct tatataggag atgcacatgt cggtaaaaat gtaaatattg gatgtggagt
    36541 agtatttgta aactatgatg gtaaaaataa atttaaatca gtagtaaaag acaatgcgtt
    36601 tataggttca aattctaatt tagttgcacc agtagttgta gaagaaaaag gatatatagc
    36661 aacaggttca acaataacac atgatgtccc agatggtgct ttggcaatag caagagaaag
    36721 acaagttatc aaagaaggat gggtagaaaa aaagaatcaa aaagacgacc aaagtaagta
    36781 attatgtagt ttattatttt ggctaaaaaa tttagctcga aattattata aattatattc
    36841 attagtattt taaaattttc aggagggtta cataaatgaa tactagcgga agcgagatta
    36901 aaattattgc aggtaattca tcgaaagagt tagcacaaaa aatagctgac tatataggtg
    36961 tatcagtact agattgtgaa gtaggtacat ttagtgatgg tgaaatatgt gtaaacatga
    37021 atgagacagt aagaggttgt gatgtgtttg tagtgcaatc tactaacagc ccagtaaatg
    37081 ataacttaat ggagttatta atcttaattg atgcgttaaa gagagcatca gcaggtagaa
    37141 taacagcagt cattccttac tatggatatg caagacaaga cagaaaggct aaggcaagag
    37201 atccaatcac tgctaaatta gttgcaaatt taataactgc tgctggagca gacagagtat
    37261 taacaatgga tttacatgca gctcaaatac aaggatattt tgatatacca ttagaccact
    37321 tactaggtgg aacaatatta gcaaattatt ttaatgaaaa gaaaatagaa gatttggtag
    37381 tagtatctcc tgacttagga agtgttacta gatcaagaaa atttgctaat actttaaatg
    37441 gagaagttcc aatagctata atagataaaa gaagaccgaa agctaatgta tgcgaagtta
    37501 tgaacttaat aggtgatgtt aaaggtaaaa atgttatact attagacgat atgatagata
    37561 cagcaggaac aatagttaat gctgcaaatg cacttaaaga gtttggagca aaagatgttt
    37621 atgcttgttg tactcatggt gtgttatcag gtccagctat tgaaagaatt gctaattcag
    37681 aaataagtga gttaatagtt cttgatacta tacaacttcc tgaagagaaa agaatagata
    37741 agataaagat aaaaacagta gctcctttat ttggagatgc tataagaatg atattctcta
    37801 atgaatcagt aagtaaatta ttctaattta ttgtatttat gagagttgtt taaaaggata
    37861 taaacctttt gagcaactct tttttgattt tatacttatg gaatgttatt tttttcttgt
    37921 tagaaaggta tatattattg taaaaagaga ttatagttta aaattatgta tatttaagta
    37981 aaataaactt aataaagggc atattattca aaatattatg aatataaaaa atattacaaa
    38041 aaagtattga aaaaattcag attatgtagt attatgtaaa tataaataaa gaaagaggtg
    38101 tttccaatgg gaaggttaga agatgaaccc ctaataatta aatgattcag tcacaatcta
    38161 aagtgaatat aaaaatctat tgaaagttta tttataagaa ttgaaaatag tatctattct
    38221 atctttagtg tttgtgagag ggttctggat tatataagat tactgtaaag agtaattttg
    38281 cacaataagc atagctgtaa atgaagagtt tcgtttatat aatgattgtg gctgaatcat
    38341 aactataata gatagaatgt ttataataga tgattttata aaatactata ttgtaatagc
    38401 ttttagcttt caaataaata ttagcaaagg atggaaatga caatgataaa actaaatgat
    38461 aatttataaa tatctcctta cgatatataa taattgtagg gagatgtttc ttttttttgt
    38521 agagtataat ttttctagaa attctgtttc aatatgtaaa aagttggtat atataaatag
    38581 tataaacagt gttgctaaaa tatggtagat attatataat ataagtggat atgtatatac
    38641 attatgagtt atataatttt gaatttaata aaatagaaac gttgatttat gttctgtaat
    38701 gtgggcacct tagagcatat tgagttagtg gtgcaaccgg ctatgaaatt gtatttattt
    38761 atagatacta tcattttcat agcttttttt atttaaaaaa tggttatgtg ttagaaataa
    38821 atttggttag tacgtttaaa taattttact tagattttta accagatata ttataagtaa
    38881 gtattaatta aaaaatttaa gggggaataa aaatgaagtt aaaaaagaat aaaaaaggtt
    38941 tcactttagt ggaattattg gtagtaattg caattatagg tatattagca gtagtggcag
    39001 ttccagcttt atttagtaat ataaacaagg ctaaggtagc aagtgttgag tctgattata
    39061 gttcagttaa gagtgcagca ttatcttatt attcagatac taataagata ccagttacac
    39121 cagatggtca aactggttta agtgttttag agacttatat ggagtctctg cctgataaag
    39181 ctgatatagg tggaaaatat aaattgatta aagttggtaa taaattggta ttacagatag
    39241 gtacaaatga tgaaggagtt acattaacag aagcacaatc agcaaaatta ttgagtgata
    39301 taggtgaaaa taaaatatat acaagtgtta cagcagataa tttgggaaat ccattaacaa
    39361 gtaatacaaa agtagataat aaagttctat atatagtact tatagataat actgtgatgg
    39421 actcaacaaa atagttaaaa ctatattttt ataaaaatat tgtaaattta atgaaaaata
    39481 taatataaaa gacaggaaga aaatcttcct gtttttttat actattttct ttaatgttca
    39541 attatgaatg atgatataat tgagatagta aaggagtgaa acctgtggct aaaaaagtta
    39601 gaataggaga caaactggtc gaaaaaggat atataacaga agaccagctt aaatgggcac
    39661 tatcagaaca aaaaaacagt ggaaaaagac taggagaatt tctagtacaa gaagggctta
    39721 tagatagtaa cttactaata agtgtattaa aagaactctt ggatatagaa agtatatttt
    39781 tagaagggac agaaatagac actttagcta caaagatggt tccagaaaat atatgcaaaa
    39841 gatatactgt atttccattt aaaattgatg gaaataaaat atgtctagcc atgtcagacc
    39901 cacaagacag agaagcagtt caagatgtaa ggcgtatgtc tggtaaagac gtagagatat
    39961 ttatatcaag tacagaagat ataaacaaag caataggtca tgcttatgca cattcagaaa
    40021 taaataaggc aatgactgag tacaacaaaa atagaactgg tggagtaaga gaaacagtaa
    40081 tacttgaaga agatgtaaat gctgctccaa tagtacgatt agtaaataac atactagaaa
    40141 atgctgttag aatggaagca agtgatatac atatagaaca aagtgaaaat tacatgcgtg
    40201 ttaggtttag gatagatgga atgttaagag aatatatgag gatgaactca gcaccatata
    40261 aggcagtaat cagccgtatc aagataatgt cagatataaa tatatctgaa aagagaatac
    40321 cacaggatgg tagaatctat ttaaaagtag ataataaacc catagatttt agggtttcta
    40381 caatgccaac taacagggat gaaaagatag ctatgagggt tcttgataag agtaatttta
    40441 tggttagtaa agaagtacta ggaatagacg aacatggctc taagatatat gatgaattga
    40501 taaacactcc ttatggtctt atattggttg ttggtcctac tggaagtggg aaaaccacta
    40561 cattgtattc aatgttaaat caactaaata cagaaaatag aaatctatta acaatagaag
    40621 accctataga gtatgaatta cctggtgtaa atcaatctca aataaatgaa aaggcagggc
    40681 ttactttcgc cagcggactt agagctttta tgcgtcaaga cccagatata ataatggttg
    40741 gagagataag agatactgag acagcagaaa tagcaattag agcttctctt acaggacatt
    40801 tagttttaag tacattacat gcaaatacag cagttggagc aatttcacgt cttttagata
    40861 tggatgtgga aagtttttta ataacttcat ctgttttagg tgtaatatct caaagactta
    40921 cacgaaaaat atgtgagcat tgtaaggttt catatgaagc agatattgga gaaaaaaagg
    40981 ctcttggtat tgatgtaaat gaatcagtaa ctatttatag aggaaaaggt tgtgaaaggt
    41041 gtaataatac tggatataaa ggacgtctag gtatatttga aatgcttgaa attactccag
    41101 aaataaaaga gttaatagat tcatctgcaa atcaaagaga aattttaaag atggctagaa
    41161 aacaaggcat ggttagctta aaagaggata tagttaaaaa ggttttaaat ggaaagacaa
    41221 cagtagaaga aatgattaga ataattttga tgactgatta aaggatgata ttatgaaaag
    41281 ttttaaatac acagtaataa aagaggacgg aaaaaagcaa actgatgtga ttgaagccaa
    41341 cgattttaat gaagctagaa atcttcttag aaagagaaat cttagagtta ttgaaatcaa
    41401 agaaagcaaa aataaaaata taagattatc tagtagaaag agaaaaaaag acttgggagc
    41461 tgaccagata agccactttt gtagacagtt tgctattata gtatcttctg gtataaatag
    41521 tatttcagga ttagaaacat tagctagaag gtcaactaac attacattaa gagaagaaat
    41581 taatcgtata gtggcagaaa taaaagtagg ttctactatt gcagattcaa tgctttcatc
    41641 aaaatcaaag tttccaaagt tacttggtgc tatggtagct acaggtgaag ctacaggtaa
    41701 attagatgaa gtattaaaaa gtatggcttc attttatgca agtgaacaca gggttaaaca
    41761 aaagcttaga aatgctgcaa catatccatt aatagttttg atttcttcat ttataatgat
    41821 ttttatattt acaacattta tggtgcctaa gatgattaat tcaattacaa cagtaggagc
    41881 aactcttcca cttataacaa gaattgttat ggggtttggt atgtttatga agaagttttg
    41941 gataatagta cttttagtta ttatattatt tatctatcag tttaaaaaat atttaaaaac
    42001 gtcagttgga agggctcata aagatagagt tataaacaag atacctgttt taggaaaagg
    42061 aataaattgt atggtagcta cacgattttc aagagcattg tatctatttg tatcaacagg
    42121 atacccatta gttcaagggc ttgattatat tatagatagt gtaaataaca ccatggcaga
    42181 gaagatttta gcatcagcta aagatggaat aacaagagga gaaggcttag cagaaaattt
    42241 agagagatat acgtattttg actctgtgtt ggtacagatg atagctatag gggagcagac
    42301 aggggaatta gagaatataa gtagacagat ggcagaattt tatgagtatg aatccgagat
    42361 ttatttaaat aggatggcct caatgataga gcctgtttta ataattgcag ttggtattat
    42421 agttgcgata ctggttgtat caatatttat gccaatgctt agtatatatg atgccatgta
    42481 ggagggaaag gacaaatgaa taaggtttat gtatcatatt atggcgattc tatttccata
    42541 gttgagggca gatataaaca cgataaggat aagttttatg taaaaaattt taatgtgttt
    42601 tcaatagagg atattgcaca agatttttct aaggaaaagt atgctctatt gagatacgca
    42661 ttagaaaatg ttaagttaaa atcaagacat gtagtttttt gtttaaatac aagagatgta
    42721 attttaaaac cccaaaaact tcctaatatg gacaaaaagg atttagatgg atttatgaag
    42781 ctagagatgg acgaaatgat ggctttggag tcagatgaat atgtattttc gtatgaagta
    42841 tctagtgaaa cacatgataa ttcagatggc gatgaatcaa gcttaaatct tatcattgga
    42901 gctatacaaa aggaagaggt aaatgcaatt gtagagataa tgcatgaatt tgatttagta
    42961 ttagatagaa tagatacatt atcaacagct tacttaagaa tgcttaaaaa tttagactac
    43021 aatgatataa tggtaaccaa tataagtgac aatagtacaa ttataaatat atataagaaa
    43081 gatactttat ttattagtga taatatacct ataaagataa ctgctaaaga tatggacatg
    43141 caattattaa atgtagtaga agaatcaaaa ggtcttatga attactattc gtcaagaaac
    43201 tttggtaagg ttacggatac tatattaata ttaggaaaaa gatattccaa taaattaatt
    43261 tatgaaactt ttagctctgc attttcaagc tatgtttctc aaggccttac tgagataatg
    43321 gatatatctg atatgataac tggagatata gatgaagatg atataaattc aattgtagag
    43381 cttttaggaa gtatgataga acctaaaggg aaaagagatt ttgaaaatat aaacttttta
    43441 ccaatggata tacttagaaa acagataaaa gctaaacaaa tgaaaaacat actgaaaatt
    43501 gctccaatag ttattttgat tcttgctata ccttatttat gtttaatttt ttcaaataat
    43561 ttagcaaata aggaacttga aaatgttaat ggtgaaataa gaaatattga atctgcatat
    43621 tatcagattg gaaatataga aaaaatgata cagagtaaaa gcgaagaaat aaaggtatat
    43681 gatatgttaa ttgggaaaaa ggtaaagtgg gaaaatttat tggatgatat agataaaaat
    43741 actccaagta aagttgaact aacaagttta tcaacaactt atcaaaatct tggaactaat
    43801 aataaagctg ataattcaaa aagtaataag actacaacag ataaatcaag taacaatgaa
    43861 acaaaatcaa gtacgaaaag tgatagtaat ggagataaaa cagataatga tttaaatgaa
    43921 gataagacta caaatgtgtc agaagcatta actggaaata gtgagactaa tagtaataac
    43981 acggataaag atgataaaac tccattgtat gataagatac caaatgttat aaatatagaa
    44041 ggaaatgcta aagattcctc ttatgtaggt caatttttat ataaattaaa gggattatac
    44101 tatttcaagg atgttaaatt acatagcata aaaagtaatg cagaagattc taactataca
    44161 tttagtatga cattatacct gaaagaaggt gtattaacta atgaataaag atatatttaa
    44221 aaaagatata aaagatatat ttaaaatgga agttagtcta aaagggattc ttataaaggt
    44281 tataatttta ttagctattt tatcatatgg ttattttgga ctttaccctc aatatcagaa
    44341 atatattgct acaaaaaatt ctgtaaaaca ggctactgaa aaattaaata tatataaaga
    44401 gaaaactgca cttatgccaa aatatgaaaa acaacttgaa gaagttgaaa gtgaattaaa
    44461 agaaaaaagc aaaaatcttt tatatgatat gcaagatggt ctttttttaa taggtttaga
    44521 taaaaaaatg aaggcttata atattgactt aactagttat gacgttggaa atgttaaaga
    44581 atacgaacat ttttatggta tatcaacaac aataagtgtt agaggtgatt atagaaatgt
    44641 caaaaaatta atggcttatt tagaagaaca aaaaaatgtt actcaaatac tagattatac
    44701 aatgacttca tatatagaac cagaaaaaga agaggaagaa acaacaaaca ataaggattt
    44761 aattaaaaat gtgaacataa ataaagatac aaaaatatac tgggtggaag gcgaaaataa
    44821 gtggcattta tataaggatt gtccattgat aaaagaagga gagattctaa aaaatgacaa
    44881 acttttagat aggtctacta attatctatg taatacttgt gtacttagag ctgcaacaga
    44941 aaaagaagca aaaaaagaag tcgtagctcc aaaggcagaa ggtgtagtag atgctacatt
    45001 taaatttata atgtacacta aagagaatac tacaatgata cttgatacag ataatccatc
    45061 ttcatggaga ccaggaaaat ataatccatt taagtctagt gctaaataaa gctaagtaag
    45121 ctttaaagat aggtgatgag tttgtacaaa aataatgaaa aaggtcttac tttattagaa
    45181 gtaataatag ctgtttttat actgacaata gttttaagta tttcttataa agtgttcaat
    45241 ggtataacat cagcagtaaa aaagcaacag attattacag atgctcaagt aaatattaat
    45301 ctaattaata agtatctaaa tagagatttg gaaaactgta aagagctaac taaaactggt
    45361 tcaggtaata attatgaata caatatagag atgccagata atgttgtaaa atatgaagtt
    45421 tctatagaaa ctaaaaaaaa tacagaggta tattctgtaa cgagaatcca aaacaataca
    45481 attgatacag aaaatgaagt tagagaagag ataatctata atcaaccact agttcaaaac
    45541 aataaagaaa tgaaggaaac accatttaaa atagaaaagc aaactggtaa atctatttat
    45601 actgtaagta tatactataa tgaatcagtg caagaaagtc ataaaaatag caatttaaat
    45661 aacaaaactt atacatttga tgttatgtca agaatagggt aataagaatt tattaaaaaa
    45721 taagtaggtt gataaaatat gagtaaaaag aatagtgaaa gaggattttc cttaattgaa
    45781 gtgttagtag ctatggctat tatgggaatt gtactatttg cattttttaa tattatcaat
    45841 actaataaca aagcaaacac taaaaatgac acagatataa cttccttaaa ctatgtccaa
    45901 agtgaaatag aaaatctaag agaaaagata aaaagtggag aatttgattt tgatagttta
    45961 gataaactag aagatggaac tgtcgtatat gaaaaattaa tagataaatc aaaaaaagtt
    46021 gtatatgata aagttcttag tgaaggtgac gtgagcttat atgatactcc atatgaaaag
    46081 attacaacaa taaaagatga agatggtaat ttaatcgaca aaggaaatat tacaaataag
    46141 ataaagacta ttgtagaaga taaaagtggt cagatatata aaatagctgt aactgggaaa
    46201 agcatgaatg actattcaag taaaaaagag gttaaaattg taactgaaat atttaaagat
    46261 aaataatttt acttgggggt gagattttga ggaagtggaa taaatttaaa agtgaaagag
    46321 gggcagcttt agttttagtt ttgattgtag tagcattgct ttctattgtt ggattgatat
    46381 tttcaaatca gatagctaat agaataaaat ctacaaagac tactaatgaa ggtatacaag
    46441 caaagtattt agcagagaca tgtgtggaaa atagtattga taaagcatat gaaaaattgt
    46501 atgatgagct tgagaaaatg gataatgagt ttaaaagtga aaatcaagaa aaatccatat
    46561 ctaggtcaaa attaagaaat atatcagatg aagattttaa taatcaagat gagaaaaata
    46621 ttgaagcaga aagacttgga tatatgaata atataaattt ctatttaaat aaagcttctt
    46681 cagacttgga aaaagctagt atggaattga aaaagctata tgatttagat atgttggact
    46741 atagagacat tgaatatgta gatgcaaata ttatttcaca tagagattct atcttagaaa
    46801 tttgcaagaa ttatacttct ggagatatta gtaaaataaa tgaatatatt ctgaaagaag
    46861 atatagactc aactacattg attgaggcaa agttagtgaa taatgatatt cttttgaaaa
    46921 tgtttttaga agaaaataaa attgaaaatg aacatttaaa ttcagccttt tcacatactt
    46981 ataaggcatt agataacatt tctttggcga tgcaaaatat gattgagtat agacatacgt
    47041 ttcatataga tgagccaaaa gtagaagtat ctaatgggat tccagattct caacaatatt
    47101 atgaactaat acaaaatcct ataataaata gtatggagta tatctggaat agtaaatggg
    47161 atacattaga aaacctattg gaaattttac caaatcaaac tcaaggattt aattctttaa
    47221 gagttcattt gagaaataat gtaagaaaat ttgagaagtt aagcgataat atatctagtg
    47281 gtaaaaaaaa tacagcaaaa aattttttaa agtataaaga gttattgtat gaaatatcag
    47341 accaatgtaa tcaactaaaa agtatgtctt atgagaaaat acctgttaaa tatgataata
    47401 tggctttgat aacaactttt gactatatac aaaatgagct tttagcagag ataaaatgca
    47461 gattaaaaga attaaaacca caagaaattg ataaaacaga aggtattact ataaaaatac
    47521 ctttttataa ggctgactac gacatgacaa aagaaggatg gcctaaatta aaagaaaatg
    47581 gttcaggggc ggagttaagc ttaatggtaa ctggtgataa agatggaata aaagaagtag
    47641 aagttacaga tggtaaaaaa aatattattg gtttaggtgt tgaagaaaat tcaaattcaa
    47701 agtataaggt tgacgccatt gtaaacttta atctaaatat agatacaaat gtagttggaa
    47761 attatgatat aaaagataaa attttgatta atcatgatat aagttcatac aaaaaagtaa
    47821 actaaatata agaagcaact tagtataaat aaataataaa ataattttat tatttactac
    47881 taaaaaaata agtaaactaa tagaagatat ggagagtaaa tattatgtat atttatgatt
    47941 tattagagca aggtataaga ctaaacgcat cagatataca cataacagtt ggaacaaatc
    48001 ctgtagctag agtaaaaggt ggatttgtaa aactaagtga acaaatattg acatcagaag
    48061 taacaatgca aatggcaaaa gacatagcgg gggaatctat ttttaaagta atagaagaac
    48121 atggagaagc tgatttttca gcttctctaa aaacaggaga aagatttagg gtaaatgcat
    48181 ataggcaaaa aggaaattac gcaatagcaa taaggactat aacagcagaa attccaacat
    48241 ttgaaaaatt aggccttcca gagagtataa aatcttttac tgaaaagcat aaaggattag
    48301 ttttagttac aggtccaaca ggaagtggta aaagtacaac acttgcaagt atgataaata
    48361 taataaatga aaaacaacaa aaacatataa ttacacttga agacccgata gaatatgtac
    48421 atcatcataa acaaagttta gtaaatcaaa gagaagtagg aactgataca gaaagttttc
    48481 attcagccct tagagctatt ttgcgtcagg acccagatgt aatactaata ggagagatga
    48541 gagaccctga aactgtttca atagcattaa cagcagcaga aacaggtcat ttagtatttt
    48601 caacactaca tacagtaggg gcagctaaga caattgatag aatagtagac atgtttcaac
    48661 catcccaaca gcaacaaata aaaacacagt tatctacagt ttgtgaaggt gtggtatcac
    48721 agcagttact tcctacagca gatgggaaag gcagaatagc agcaattgaa ttgatgtttg
    48781 ctactccagc aataaaaaac ttgataaggg aaggcaaaac atatcaaatt ccaaacatga
    48841 tacaaactgg agttaaagta ggtatgaaaa ctatggacca agatttaatg gaactttata
    48901 aaaatggaaa gattacaaaa gatatggcac ttagtaggtg tactgaccaa gagtttatga
    48961 caagaatgat aggtggagta aactacaatg gatattataa tcgttaatct atatgtattt
    49021 atagtgggta tagtgtttgg aagtttcttt aacgtctgta tttttaggat tccagaaggt
    49081 atatctattt ctagacctcc ttcccattgt atgagttgta atactagact aaagccaata
    49141 gacttaatac cagtgctaag ctatttgatg agtggcagaa agtgtagata ttgttatgag
    49201 aaaatttcta gtagatatgc tatagtggaa ttaattacag gaattttatt tttaacagta
    49261 tttatgttat atggaatatc tacatcaact atttattatt tggttcttgt gtctttactg
    49321 attataatta catttataga tattgaccac tttataatac cagataaaat attgattttt
    49381 ggagctatat tttctatgat ttttaacctt ttatttaaag aaattccagt taaggattca
    49441 attctaggtg tttttatttg tggaggaagt gtctggatta tagttctttt gattgaattt
    49501 gtaataaaaa aagagtgtat gggtggagga gatatcaaac tatttgcaat gctaggcctt
    49561 tacatgggtg ttaaaaatgg tcttttgaca gccttactaa gcgtttatgt aggagcagtc
    49621 tatggaatct gtgtaataat tataagtaga ataaaaggaa aggaatataa ttctgttata
    49681 ccatatggac cttttatatc tattggagca ttaataacaa tcttatgtgg aaagcaatta
    49741 cttgaacttt atttttctat ggttatatag atgatagtca agttaaataa agttttaatt
    49801 taaaaaaatg aattaaagta tttaataagg acaatattat tattaaccct attactaaag
    49861 tgctacaaac tatggagtat ataataataa tttccttatt ttttgcacat ttgataaata
    49921 aatctctatg tgttttttgt gatagagaaa agaaaaattt atataatacg ttttttattt
    49981 acataataac tgtagtttta tctgtattaa tatatctaaa atttgggatt agtgtagaat
    50041 gtgtacaata tatggtttta attccatttt taataattat atccattgta gattactaca
    50101 caatatatgt atatgatata acaatagtta gtggtataat agttcaaggt ataatttttt
    50161 tggccttttt caatatagct caatttgatt atataaatca tatatttgga ctattgatag
    50221 gctttattat accttatatt attgctaaac taacaaaagg attaggctat ggagatgtag
    50281 gtctctatag cttatgttgc tttgcattgg gaaataatta tgggttttat gtgatagttt
    50341 tatcatttat tttagcgttt ttgtttttta ttattttata cataactaaa atatttaaag
    50401 atgtagatat aagaaagcaa attcctttta caccttttat ttccttgtca acaattttaa
    50461 taatatttac agagtataat atatttaatt tttattataa tttgttatac aaatttatat
    50521 aacaggaggt aagaaatgta cgtagtagta gggttaggta atccaggaaa gaagtatgag
    50581 aagactagac ataacgttgg atttgatgtt atagatattc ttgctaaaga atacaatatt
    50641 agtgttacta aaataaagca taaagctttg attggtgaag ggagagtagg tactgaaaaa
    50701 gtattattag ttaaaccaca aacttatatg aatttaagtg gagaaacatt aatagatata
    50761 tataaatatt ataaggttga tttaagtaat atagtagtag tatatgatga tatagattta
    50821 gaagttggaa agatacgtat aagaaaaaaa ggaagtggag gaactcataa tggcatgaaa
    50881 tctataacta agtgcctagg ttcaaatgac tttccaagag tgagagtagg tgtatctaaa
    50941 ccagaagctg gtcaagactt agcagacttt gtactttcta gatttagaaa agaagaatct
    51001 gataacataa atgaagcatt agaaaaagcg gcagatgcta ttgactcaat aataagagaa
    51061 aatatagata tgtctatgaa caaatataat ggatagtgag agggagattt aaatgaatga
    51121 tgttttttta tatcctttgc aaaattcaaa agagtataaa gatataataa actgtataaa
    51181 aaatacaaaa ggctcattat tggttaatgg acttttacca gtacaaaaac ctcatatatc
    51241 gtattctata tttaatgatt tatcacgaca aatgattttt ataacgagta gtgatttaga
    51301 agcaaagaaa gtatacgaag atttaagttt ttatatggaa gataaagttg aatatttagg
    51361 ttttcaagat atttattttt atcacttgga tgcaaaggac agaaacgaag aagcaaagaa
    51421 attaaaagta ttgttaaaac tagcaaataa agaaaaaatc attttagtaa cttctattga
    51481 ggcagtttta agaaaataca taccaaaaca agttttgctc gatagtgtat ctcattataa
    51541 ggtgggagat agcttagact tagaaaagtt aactgagaaa ttagtttcat tgggatatga
    51601 aagagtttca aaaatagagg ggtttggtca atttagtata agaggtggaa ttattgatgt
    51661 attttcactt gaatatacaa atccaattcg tatggaatta tttgatgatg agatagattc
    51721 catacgaact tttgacgtat attcacaaaa atcaattgat aaattgcaac aattctctat
    51781 aactccatct agagaattta tttatcccga aaaaactaca gatgcattag ttaaattaaa
    51841 aaaagaaaca actaaaaata ctgatgaagg tacatttcaa aatatagatt atatatcaag
    51901 taagacttat tttgaaggtg cagagaacta tatagattat atttatccag aagaaaacaa
    51961 aagtatattt acttatttag cagatgatgc aatagtattt attaatgata taacgagact
    52021 taaagaaaga tgcgaaaatt atataaatga gtttagagaa aattataaat taaatcttga
    52081 aagaggtctg gctattaaaa accaaggtaa attgttatat cactatacag atttagagta
    52141 cttagtaaaa gacaagtctg tggtattaaa ctcgctattg ccaaagtcta taaataactt
    52201 ttctataaaa tctataataa attttgaaag tagagaagtt cctacattta atggaaaggt
    52261 agatttgctt gtagaagaat taaatcggct gaaatataat ggatacaaaa taattttagc
    52321 aacaaatacc ttagaaagag caaataaatt aggaaaagat ttattggaca aaggcttaga
    52381 aacgaccatt tctaaagata gagatattga aattaaatct tcacaagtta taattgtacc
    52441 tgcacacata aacagtggtt ttcagtataa atctataaag tttgttgtta taacagataa
    52501 cgaaatgata ggtgtttata aaagagcgtc taagactagc aataaaaaag ttaaaaaagg
    52561 aaagaaaata gaatcctttt tagatttaag tgttggagac tatgtagttc atgaaaatag
    52621 tggtgtaggt agatacacag ggattgaaca aattacagtc aatgctatta aaaaagatta
    52681 tatgaaaata gtatatcaag gtggagataa tctatatgtg ccaatagacc agatggacaa
    52741 agtacaaaaa tatattggtg cagaagtaga aaaagttaag ttaaataagc ttggaacaaa
    52801 tgagtggacg aaagcaaaag caaaagttaa aaaagaaatt gaagatatga caaaagactt
    52861 gattgagctt tatgcaaaac gtgaaaaaat acaagggtat aagttttcaa aagatacacc
    52921 ttggcaggca gagtttgaat cgttgtttcc atatcaagaa acagaagacc aattaaaggc
    52981 tatagaagaa actaaaaaag atatggaatc aagtaaggta atggataggc tagtatgtgg
    53041 agatgttggt tatggaaaaa cagaggtagc tattagaagt atttttaaag cttgtatgga
    53101 ccaaaaacaa gttgctgtat tggttccaac aacaatattg gcccaacaac attataatac
    53161 attcaaagag aggtttgaaa attatccttt gagagtagaa gttttaagta ggtttaaaac
    53221 accaaaacaa caaaaacaga ttattgaaga tgctaaaaaa ggattagtag atattttaat
    53281 tggaacacat agaataatat ccaaagatat aaatttacca aacttaggtc ttgtagtcat
    53341 tgatgaagaa caaagatttg gagtaaaaca taaagaagct ttaaagaaaa ttaaatctac
    53401 agtagatgta cttacacttt cagcaactcc tataccaaga acattacata tgtctttaag
    53461 tggaataaga gacatgagtg ttatagaaga acctccacaa gaaagacatc ctgtaataac
    53521 atatgttaca gagagtaagg aaagcgtaat tcaagatgag atagagagag aattaagtag
    53581 aggtggacag gtattttttg tatacaatag agttgaacac attgaagaaa tggcaagtat
    53641 gattcaaaaa ctcgtaccag atgctagagt ggctgttgca catggaagaa tgacttctaa
    53701 atcattagaa aatataatcc taggattttt aaataaagat tatgatgtac tagtctgtac
    53761 tacaataatt gaaactggta tggacatatc aaatgcaaat acaatgatta tatatgatgc
    53821 agataaaatg ggattggctc aactttacca attgagaggt agggttggaa gaagttcaag
    53881 acaaggatat gcatatcttt tgtatgaaaa agataaaact ttaagtgaga tagcggagaa
    53941 gagattaaaa gctatcagag aatttacaga gtttggttct ggttttaaaa tagcaatgag
    54001 agacctcgaa ataagaggag caggaaatat tttaggttct caacaacatg gtcatatggc
    54061 agttataggt tatgatttgt acgttaaaat gcttaatgat gcaattaaaa aagtcaaagg
    54121 tgaacctatt gtggaggaaa ttgatgttga aatagattta agtgtaaatg catacattcc
    54181 agataattat atcaaagatg agttgattaa aattgaaatg tataagaaaa tagcttctat
    54241 tgaaaacaaa gaagacatgt tggatataca agaagaactt gaggatagat tctctgatat
    54301 acctaaacca gtccagacac ttcttacaat agcttatata aaatcgttat gtaagatatt
    54361 aaaaatagaa aagataagac aattaaaaga tgaaatatta ttagttccaa taacaaagta
    54421 tagaactaaa cagaaaatag gttataatat agttacagaa ttagaagaat tattagaaaa
    54481 gatgtgcaag gtaaaataac ttgtaaattt aagaagggat gttttaaatt tgaaaaaagt
    54541 aataacattg gtaatagcta tgattttggt agtatctgtg actgcttgca gttctagtaa
    54601 aggagaaact gtggcaacag ttgaaggtac aaagatatca tcagatgaat ttaaaaaaac
    54661 tatagctctt tataaagatt ctatggaaca aacttatgga aaagatatat gggataagga
    54721 agttgaaaag ggtgtaaaat acaaggacaa gtttaaagat ttaattcttg accaacttat
    54781 aactacagaa gtaatatatt ctcaagctaa aaaagataac ttacttccta aaaaagagga
    54841 tgttgaaaaa agttttaaag aattaaaaga cgctatgggt aaagatgaaa aatataaaga
    54901 acaacttaag aaattaggta tagatgatga gtttttaaga gaccaacaag agaaagattt
    54961 agcaatgcaa aactatcaaa gtaactttgc taaaaagact aaaatatcag atgaagaaat
    55021 gaaaaaatac tatgatacac ataaagatga atttaaaaaa gatgaggtag aagcttctca
    55081 tattttattg aaaacagtag atgataataa caagccactt tcagataagg aaaaagctga
    55141 agctaagaaa aaggctgaag aggctcttaa agaagttaaa tcaggtgagg attttgcaaa
    55201 agtagcaaaa aaatattcac aagatacttc agcaagtgat ggtggtaaat taggattctt
    55261 ttcaaggggg caaatggttg ctgaatttga agatgctgct ttttctatga aaaagggtga
    55321 agtatctgat ttagttgaaa ctcaatatgg ataccacata attaaagtga cagacagaat
    55381 aaatgagcaa acatcatttg aagatgctaa agaaactata aaagaccaac tgttgaaaaa
    55441 taaatatcaa gaacaaatag aaaaattaac taaagaagct aaggtagaaa aagatgaaaa
    55501 agtaataaat aaaatcacaa tctaagactt aaaaaaagag taatatgctt aaaaaagcta
    55561 tatctggata agatatagct ttttttgtat atttttctta acaatggtaa aaataaactt
    55621 aaagtaattt atggagggat taaaaaatat gaaagcaaca ggtatagtta gaagaataga
    55681 tgatcttgga agggtagtta tcccaaaaga gataagaaag acattaagaa ttagagaagg
    55741 agacccttta gagatattca cagcaaaaga tggagaagtc atacttaaaa aatactctcc
    55801 aataggtgaa ttaaatgaat tttcgcaaga atatgctgaa acattagctg aagtactagg
    55861 atatggagtg ttgataacag acttagattc tataatagct gtgtctaagc ttcctaaaaa
    55921 agattataaa gaaaaaagta taagtgatga gttagaagca ataataagtg aaagaacagt
    55981 aaaatattca aaagataaaa acattttacc attattcaag gaagaccaaa aagaatatac
    56041 tagtcaagtt atcatgccta taattagtgc atctggtgac tgtataggtt caattgtagt
    56101 tgtttcaaag gataaagata caattgcaga aagtgaagaa aaatctttaa aaattgctgc
    56161 taacttttta ggaaaacaag ttcaataatt ttatcataaa gaccttttac atgaaggtct
    56221 tttgaagttt ttgtgtaaaa tattgaatat agcattaaaa atatggtata ttaaagtttg
    56281 ttatataaac agtatggagg ttatgttatg aacaataaca aaaataaaga ctcctttcta
    56341 aaaggagccc ttatacttgg gctagcaggt gtaatcgtaa aaataatggg tggatttttt
    56401 aggattcccc ttggaaacat gattggttca gaaggaatgg gatactatca ggctgcttat
    56461 cctgtgtata ctctattttt aacattagct actgctggat ttccaacagc tgtggcaaaa
    56521 ttggtttcgg aaaaagttgc aattggaaat tttaaaggtg caaataagat atttaaggta
    56581 tcacatacag ttttattcat taccggtata atatcatttt gtatattatt ttttggagcc
    56641 gactacatag taacaaacgt aatgaaaaat ccaggtgcgt tatactctat gaaagccatt
    56701 gctccagcat tactatttgt tcctgcaatg tctgcatata gaggatattt tcaagggaga
    56761 caagatatga ctaagattgc tgtgtctcaa gttgcagagc aattttttag agttgtatta
    56821 ggtcttactt tggcctactt gcttatgaag agtctaggtc agacttttgg tgcagcaggt
    56881 gctatatcag gggctacaat aggttcaata gcatctatgc tttatttggt gtttgcttat
    56941 atgctaggga gaaaagagcg tagagcagag atagatgcaa gccaaagatt taaagatgaa
    57001 agagtgtctt atatttttaa aaagctttta actgttgcca ttcctataac aataggagca
    57061 tcagtaatgc cacttgtaaa tatgatagat aatgttattg taataagaag acttatggaa
    57121 gcaggattta catacaaagt ggcaaattca atgtttggtc aattaacagg tatggcaatg
    57181 gccacaataa atttaccagc agtcataaca actgcaatga gtatgagctt agttccagca
    57241 atttctaaag catatgcatt aggaaataag tcaaaagcta gaaaagatac taagagtgca
    57301 gttaaggtaa ctttacttat agtattgcct tgtgcgtttg gtatggcttc tttagcaata
    57361 ccaataatgg gtcttttatt tccacatgaa ccatcttctg taggaactat tttgtttact
    57421 cttactccat gtgtattatt tttaggatta atacagacat tgactggtat aattcaggga
    57481 atgggaaaac caatagtacc tgtaattgct ttatgtgttg gtatgctatg taaaattgta
    57541 ataagttata ctttaacagg tataccagat attaatgtac tgggttcagc atttggtaca
    57601 gttacagcat actttgtggc agccatgatt aacttactat atgttaaaaa acacatgaat
    57661 gtaaactttt ctaaaaaaga atttataata aagccattta taacagttat gacaatgttt
    57721 ataatggtta agttgagtta tggtgcttta gttggattct taggaaacag catatctaca
    57781 ataattgcaa tatgtgttgg tggaattgta tatgtagtag taatacttgg aataggtgga
    57841 attaaaaaag aagagattct aactatgcca aaaggtgata aattatataa attgttaaaa
    57901 aaagttaaac ttataagata atataggaat atatatgcaa ataaaggaaa tactatacaa
    57961 atagtaaatc tccttatttg tataataata taaaaataaa gtgaaatttg ctaataggag
    58021 tgatgttatg ggtaagataa gtattgtagg tcttggacca ggagactatt ctcttataag
    58081 ccaaggtgtg ttagaatctt taataaatag ccctaaagtt ttttttagaa cagagaaaca
    58141 tccaataatt gataaactta aagaaactat acaatacact tctttagact acttttatga
    58201 aaaagaggaa aattttgata atgtttattt gaaaatatct gaatttatca tagaagaatc
    58261 agcaaagggt gacctagtgt atgctgttcc tggtcatcca agagttgcag agaagactgt
    58321 aagtataata gagagattag ccaatgaaaa gcacatagca gtagaaatat tgccttctat
    58381 gagctttgta gacgctatgt ttaactattt ggctatagac ccatctgagg gatttaaact
    58441 ggtagatgct tttgaaatag aaaattcata tatagacttg gatacaagca tgataataac
    58501 tcaggtatat gataaattta tagcatctaa tgtaaagtta aaacttatgg aacattatga
    58561 ctataatcaa gaagtatgta tagtaaatgg agcaggtgtc aaagatttag aaagtaaaaa
    58621 gtttataaag ctttgtgaat tagacagaaa tgaaaacttt tttgactatt taactagctt
    58681 atatataccc aaaagttcta aaaagatgta taatacagta catgacttag aaataatagt
    58741 taatacactt agaagtccat ctggatgtga atgggataaa aaacaaacac atcaatcatt
    58801 aaaaaattct gttatagagg aagcatatga actttgtaat gcaattgata ataatgatat
    58861 agatgaaatg gtagaagagt taggtgatgt tcttttacag gttatattcc attgtcagat
    58921 aggaaatgag gagggctact ttgatttaaa agaagtagta aatggcatat gtaaaaaatt
    58981 aattcataga catcctcata tatttagtgg tgcaaaatta gatatgtcta agtttgagaa
    59041 aacttgggaa gaattaaaga aagaagagaa aggcgaaagt actataacag atggccttag
    59101 aaggatacca aaacatttac cagctcttat gaaggctagt aaagttcaac ataaagcagc
    59161 acttgtcggc tttgattggg acaatgtaga agatgtattt aaaaaaattg aagaagaata
    59221 tcaggaatta cttgacgaac acagggtcgg gaatataaaa tacataaagg aagagctagg
    59281 cgatttatta ttttcgatag taaatctagc tagattttta gacatagact caggagaagc
    59341 cttgaactgt actacagaaa aattcataaa tagatttgac tttatagaaa aaagtgcaat
    59401 gaacttgaat aaaaaattag aagacatgac acttgaagag atggatgagt tttggaatca
    59461 ggctaaaaaa caataaaatt gtggaaggaa atttgtcaaa aatctagaac ttttatcaca
    59521 aagatagaag tctatattat aaacattttt aggaggtaaa tatcgtgaat aaagctgaat
    59581 tagtatcaaa gatggcagaa aaaagtggat taacaaagaa ggaagcagaa gctgcgttaa
    59641 acgcatttat gagttctgtt caagatgcac tagtaaataa tgaaaaagtt caattagttg
    59701 gatttggaac atttgagaca agagaaagag ctgctagaca aggaagaaat ccaagagatc
    59761 cagagcaagt tatagatata ccagcttcta aagcaccagt tttcaaagct ggaaaaggat
    59821 taaaggatat aataaatgga taattagaaa tcttgtgaaa aagtgtggat aaatttgcca
    59881 cactttttct atagaaccaa ggaaggtgat aattatgaga ttagataaat ttttaaaagt
    59941 atctaggatt ataaaaagaa gaactgttgc taaagatgca tgtgataaag ggattgtcac
    60001 tataaatgga aaagttgcta aatcttcttc agaggtgaat attggagata cattagaaat
    60061 acaatttgga gagaagaaga tgaagtttaa gataaatgaa gtaaaagagc atgtattaaa
    60121 aaatgatgca aaagaaatgt acgaaatttt agaataaaat taatagtcct ctagtatatt
    60181 aatagtagta ttattgaaat atttactggg gggatattat ggaacagaac ataactttga
    60241 aagatagatc aaagctggtt atttcgggag tcgagcacat atactctttt aatgacaaaa
    60301 gagtagagct caaaacttct gtaggcgaga tggtaattga aggcgaaaac ctagatatga
    60361 gcaagctaag tatagacgaa aatataatta gcatagatgg aactataaat tctatggtat
    60421 atgcaaagcc taaaaagcca caagagagtt tcttgaaaaa ggtatttaga tagatgatac
    60481 cttttactca agatgtaagc attttttatg ctactattta tggtggaata ctcatagggg
    60541 tgttgtttga tttttataga gggctaagag ggaattttaa attcatcaat tattttgcta
    60601 taatctttga tgtattgttt tggtttctag ctacggttat aatattcgta acaataaacc
    60661 ttacagaatt ttttgattta agatattatc attttgtggc tttgtttatt ggttttattt
    60721 tatactataa caccataagt aaaattgttt tatcaattat caataaaata attcgttttg
    60781 tgagaaattc ttttaaaaaa gttacacatt acatagtcag ttttttaaat aatttgtatt
    60841 acgttataat ctattcacta cacctactat ttgatattat attttatata ccaaacatat
    60901 ttatagcaac aagaaaaagt ataaaaagaa aatcaaataa aaaattaaag aacaagaaaa
    60961 aatcaaaacc taagaagaaa aaaaataaaa ctaaaaaaag ggtgtaggaa aaatgaactt
    61021 aagaaaaaaa ttttcaggac agattattgt tatcagttta tttttaggaa tatcaatttt
    61081 tagtatgatg acaggatttg tatttgagta tacaaaagct aaggaatata aaaaagaaat
    61141 agcaagtcta aataaacaat taaaaaagac tgaaatacaa ataaacagct taaagaaaga
    61201 tgaaaaatca tatgaaggag acttagagga tatagcaaga aaaagattga atatggtaaa
    61261 accaaatgaa acagtttatg tagacataaa tcgttgatta aaacttgcta ataagtttac
    61321 agatgtattg attttaaaat ttaagattta ataaaaaagt cattcagtta aggatggctt
    61381 tttgttttta ttgaggaggg aatttcataa tgaaagtagg agctatagat attgggacaa
    61441 actcaatgag attactgata gcagattata gagatgggaa ttttataaac agaaaaaaat
    61501 ttgttaatac aactagaatc ggttatggtg tggatagtaa aggatatata aaagaagatg
    61561 ctatcaaaag aaatataaaa gcattaaaag aattttctga taagtgtaat gatgaaaagt
    61621 gtgaaaaaat ttattgtatg gggacatctg ctcttagaga cagtaaaaat ggagattact
    61681 ttgttaaatt agctaaagaa gaaactggaa tagatgttga tatagttacg ggaatagaag
    61741 aatcaaattt gggctttaag ggtgttttag aaggaataca aggtgatgat actattattg
    61801 ttatagatat tggaggaggt tcaacagaat ttattgtagg tgattcagaa ggaattaaat
    61861 ttaataaaag tgagaatgta ggtgctctta ggatgacaga gaggtttttg aagcacgata
    61921 ttattgaaga tgaagagttt gaagctatga gttcatttat atatgatgag attgacaaaa
    61981 cgttaaatca tataaaagac agaggattaa aaactcttat aggtatagga ggtacgatta
    62041 catcattatc agcaatgaat caagaattag agatttactc tatggaaaaa atacataata
    62101 gtaaaataca caaaaaagaa atagaagaaa ttctacaaaa attaataaag atgacattaa
    62161 gtgataaaaa gaacttaaaa gggctacaag aaaaacgtgc ggatattata actgctggtg
    62221 taaaaatatt gaatataata atggaaaaat tagaaataga agaaataacc gtaagtgaat
    62281 acgataattt ggaaggctta atatgtcaaa agtcaaaaaa aatgtattaa tattttttga
    62341 tttttaaaac cgattatgac aaaaaaaatt actcctcttt gttacaattc ttaatataaa
    62401 caaaagagga ggttttttta tgcaaagaag tgtagcagtt gtgaagaata agactgtaaa
    62461 accaaatgtc ataaaattaa taagcggata tattgatttt actacggcgg cattcgctgt
    62521 gatgggattt ttacttagta ggtctattat agtagactct gtagctcctt taggaattgc
    62581 cttttttata tgtgcatcaa agattgataa gtacaagata cctgtattca tatcaacatt
    62641 attaggaata ttgttatcat ctaatgattt tggaaatgta gcaaaatatg ctgtgtgcct
    62701 tacaatattt atggctatga ataaaaaatt aaaattatca gattcaattg ctaaggttgc
    62761 atttataggt gcaataatac tacttccaat ctccatggga caagctttct tttcaaatag
    62821 gtatgtatat ggtcttctta tagcaggagt agaagcaata ataatgttta tatctatata
    62881 tgtgttttct tatgggatag gtttaatggc caatgtcaac aataggatgt ctgtacggac
    62941 agaagaagct atatcaataa gtttactgct aacctttagc ataatgggaa taggagatat
    63001 atctctgttt ggaatatcaa taaggaccat tttatcgacc gtattgatat tgctgacctc
    63061 aatagtaggt ggagctacca tgggagcatc tagtggtgta attattggtg tagcatccat
    63121 tttaaataat atgacatcag ctgtttatat ggggatatat tctttttcag gattaataag
    63181 tggagcattt aataaaataa ataaatattt ctgtatacta ggatatattc taagttggac
    63241 aataatatac ctatatactt ctggtattac ttctaatatg atgcaattaa gagatatact
    63301 attaggttgt ttgatagtac tagtattgcc agagagatta tttaataaga ttgaaaaatt
    63361 aataaaaagt aatgtggctt caaatgaaat cgtatacgat tatattatga gaagcaaaaa
    63421 cctaactaat agcagattga acagtattta taaaacttat gatgaccttg cagatacatt
    63481 tgataagata agagaaaaag acaaagtgct agaccaaaga gatatagcta atgtaataga
    63541 tatgattcat aatgatgaat gtaaaagttg tagtatgaga agaatgtgct gggagtcaag
    63601 atttaatcat acatacacta tgatatataa cattcttgaa aaaattgagg agaaagggga
    63661 gttaagtcta aacgatatac ctaaaaattt tagaaaggaa tgtatgaaac cagagtcgat
    63721 agtgaaaata tcaaatcact attacaaaat gtttgtatta gattatgatt ggagtgtgaa
    63781 gttttcagaa agtagaaagt taatagcaaa tcagataaga agtatttcaa aatccattaa
    63841 atccttatct caagatttag aaggtgacat aatgctagat atagaaaagg aaaaaaatat
    63901 atatgaacag ttagaaagat atgatataac agttgataaa gtaagttact taacaaaaag
    63961 taacaatgag tttgaaatat caatagaaaa gaaaacttgt catgatggat gtatgtgtga
    64021 agataaaatt gtaaatataa tttcagacct agtaggtgaa aatatgtctg ttagaaaaat
    64081 aggatgtcac tgtttaggag gtaaatgcaa ggcaacattc gttaaatctc aaaaatataa
    64141 ggctgttaca gaagtttcag caatgtcaag ggatgggcat atcctttgtg gagacaatta
    64201 cacatacatg gagataaatg atggtaaata catgatggct ataagtgatg gtatgggaaa
    64261 gggtaaaaaa gcatatgaag aatcttctgc cactattgat atactggaaa aaatgataga
    64321 tgcaaaaatt aaagatgaga tagtcattga tactataaat aatatgttgt tgttaaaatc
    64381 ttcagaagag atgttttcaa ctctggattt gggaatttta gatttaaaac gaggttgttt
    64441 agaaactata aagatgggag cgtgttctac ttatataaaa agagaggatg gagaagttga
    64501 cttaatatca tcatcatcat tacctgtggg tatattatca gatgtaaaaa ttgatagaaa
    64561 aaatgtaaaa gttaaggaag gagactatgt tataatggtt tctgatggaa ttgtagatgc
    64621 aggaagaaat aacaatttag gagacaattg gttaatatac ttcttaaaga atatagagac
    64681 tacaaatcca aaggaaattt caaatttaat attggataga gcattagagt tacaagcgtt
    64741 acaaatcgaa gatgacatga ctgttttagt tacgaaaata tgtacaaaat aaggtttaca
    64801 agattatgtg tataagatgt ggataacttg tgtataatat gttaatagac ttttgaaaaa
    64861 agtatagtta ttaacaaaaa taacatataa atcaacaaaa tttgttgata agtatggcag
    64921 aaatgttaat aaaatgtaaa aaaagaaaaa acaaaagcta ttatcaaaag agattcatgt
    64981 tgaaataact aaatttctaa gtaaagaaaa cctgtgaata tgttgattat tatgtggata
    65041 actattaatt cgatatttat ttatatagta tgaataattg aataatatat ctaaaaaaag
    65101 ccatcctatt attaagtaaa tttattgaaa ggatggcttt ttatgaatag aaaattgtgc
    65161 aaagcaataa tacctttatt tatttctatt ttttgcatgt taataataag tataaaagct
    65221 gaccaaggat atcaaaagaa taatgacaga gcaattgctg tcatgaataa taatgatact
    65281 gaagatgatg ctgaaaaaaa acaagaagta gactatgaaa aaacatgttg gaatttgcaa
    65341 tctttgttca aaagtgatga ccaatggaaa aaagaactta agagttttga taaagatact
    65401 aaagagttga aaaattacat aggtaaagta acaaaatcgc caacacattt gtcttttgcc
    65461 ttaaacatta aggaaaaact tgatataaga ctaaataaac tttctgccta tgtaaaatta
    65521 aaacaagata ctaataaaaa ttcatataag tacttagata tgagtgatag tatgagtaaa
    65581 tcatatggga attatatggg gatttgttca gatttagaat tagaaatact aaaattatca
    65641 aacaaagatt acaagaaaat tatttcaaat aaaaatataa ataggaaata tggtgcatat
    65701 ttaagagata taagaaggaa taaagtacat tatttggatg ataaatcaga agatattcta
    65761 agcaaagtat cttcaataag tagtcttcca agccaagtat atgaattatt tagaaatatg
    65821 gatagaaaaa ctaatttgac accagcgcaa tatgcaagtg aattagagtc agtagataga
    65881 gaaaatagaa aaaaagctta tcaagatgaa cttataactt acaatgataa tataaataca
    65941 attgcaggtt taattactgg tcaagttaaa aagaatattt tttattctca ggaaagaggt
    66001 tatgagtctt ctttagaaat gtacttggaa tctgataatg tagatgaaaa agtatacaat
    66061 aatttgataa ggactgtaaa tagtaatatg gacagtctac acaaatatat agatttaaga
    66121 aaaaaagtat taaaattaga taaggttcat tcatatgata tgtttgtgcc tatggttaag
    66181 gctgttgata ataatattaa ttatgaaaag gcacaaagta tagtatattc agcgttgtca
    66241 cctttaggaa aagaatacaa tgatgtagta tataaagctt tcaatgaaaa atggatagat
    66301 gtttattcac atgaaaataa agtaagtggt ggatactgct tatctgttta tgaaaatcat
    66361 ccatatatac ttttaaatta taataattca ttaggttcag tttcgacttt atcacatgag
    66421 cttggacatg ctgtatatga atacttaagt tctaagaatc agaattattt taattcaaat
    66481 ccgtctatat ttactcacga agttgcatct acaacgaatg aagcattact ttacgagatg
    66541 cttataaaag aagctaaagg caatgatgaa aaagcttatt atataacaca gtatttagac
    66601 ttgataaaag atactcttta tacacaaact atgtatgctg aatttgaaaa aactatacac
    66661 gagttagtag aaaaaggaaa aagtgtaaac gcattagtat taaatgatgt ttggggacaa
    66721 cttcttaaaa aatattatgg acaaagctat gaattagacc aattatctaa ggtcggatgg
    66781 gctagaatcc cacattttta taatagtttc tatgtctata aatatgctac aggttgtagt
    66841 gcaggagtaa gttttgccca agacatccta aagaatggtt cagataacta tatgagcttt
    66901 cttaaaaagg gaagttcaga ttatccaata aacttgttaa aatcaagtgg cataaattta
    66961 actaatacaa aacccataga aaatacaatc aaaaaatttg atagtttagt agcagaactt
    67021 gaaaagctat tataaacatt attgtaatcc acatggtaaa tatatcgaat taatgataaa
    67081 atatactaaa agtttaaagt cctatcaaga taggactttt tatttattaa ttagtgggag
    67141 atgattctat gcaagttaaa gttaaaaagg ctgtaatacc agcagcaggt ttaggaacta
    67201 gatttttgcc agctacaaag gcacaaccaa aagagatgtt accaatagtt gataagccaa
    67261 ctctacaata cataatagaa gaagctgtgg cctcaggaat agaggaaata ctaataataa
    67321 caggtagaaa taaaaaatct attgaagacc actttgataa atctgtagaa ttggaacttg
    67381 atttagagaa aaaaggtaag aaagaattgt tggaggtagt acaaaacata tctaacatga
    67441 ttaacataca ttatataaga caaaaagagc caaaaggatt gggagatgca atttattgtg
    67501 cgaggcattt tataggtgat gagccgtttg cagtaatgtt aggggatgat attgtagata
    67561 atgatgtacc ttgtctaaaa caactaacag atgcatatga ggaatataga actacaatat
    67621 tgggtgttca aaaggtaaat caagaagata ctaataaata tgggataata gaagcaaaaa
    67681 atatagaagg tagagtttac aaggtaaaag acatggtaga aaagccagag tcaggaaaag
    67741 ctccttcaaa tattgctatt ttaggtagat atataataac tcctgaaatc tttgatattc
    67801 ttaaggattt accaccaggt aaaggtggag aggtacaact tacagatgct ttaaaaatat
    67861 tatctaagaa agaagctatg tatgcataca attttgaagg caagagatat gatgttgggg
    67921 acaagctagg atttttagaa gctactgttg actttgctct aaagaaagaa gaccttaagg
    67981 aagattttat aaaatatttg aaacatgtat gtagtgaatt tgataaaaat aacaatgtgt
    68041 tatacaataa tacagatgaa aaaatagatt taattgaagt caatgaagct agagaacttg
    68101 aaattcaaaa ataattaatg aaaggtgatg tatggtggca aaatcaagtc agaaaagaat
    68161 taatagaata atagctgttg ggattgtggg aatcctcgta ataacgagta taacagctgt
    68221 tttgagtatg attgcaacta tgtaataaga taaatgacag cagttgatat acataaatat
    68281 aaaaaccata tataacttga tgtagtcaaa aacttacaat attttagtta tatatggttt
    68341 ttagaattta taaatgtaaa aaaaaatttt tataatagtt gcatatttta aaggaaaata
    68401 ttattataag atataaatat agtgataaat ttataaaaac gtgctaagat tggacttgaa
    68461 atacagtaat atagtaggta ataatgtttt aaattttatt tattgaccat aatatataaa
    68521 taatgatatt attagactta actgtttaaa taaaactttt ctttttcatg ccttcaattt
    68581 ccaaaataag tatgtatata aatgaatata tagatgagga ggattttttt gattttagat
    68641 gataaagtat tagaaggatt aggtagtaag accttagttg agctacgaga gatagctaaa
    68701 gaattaaaaa taaaatcaat tactacatat aagaaaaatg agttaattga gattataaat
    68761 tccaaaagta aaaatgagga aaaagtaaac gaagagacta aagaaaaaaa tgaagatatt
    68821 aaagaagaca taaagaatag aaaagaaaat atagagcgtg aaagtataga aaaagaagtt
    68881 gaatataaga gccctaccaa atcatacaac aagaaagaaa tagataccca aaatatttcc
    68941 caaaaccaag aaaatagaaa tcaaagaaat gactataata agacaacgag tgtaaatgat
    69001 agtaataagt catcaaatat atctaataga atggtcagaa ataataataa aaactattat
    69061 atgcctaaac aagttgatga atctaagata gtagatgaat ttaacacatc aaaagaggat
    69121 gaagtagtag gtgtacttga aattctgcca gatggatttg gttttttaag aggttcaaat
    69181 tatttgtcta ctgaaggaga tgtttatgtt tcaccatctc aaataagaag atttaatatg
    69241 aaaacaggag acaagattaa gggaataact agacatccaa aaagtggaga gaaatttaga
    69301 gcacttttat atgttcaaaa aataaatgat gaaaaccctg acacagctat acaaagaaat
    69361 gcgtttgaga cattaacacc aatatttcca gaagaacgac ttacactgga aactaataga
    69421 aatgaaatag ctacaagaat tatagattta atttcaccta taggaaaggg acaaagagga
    69481 ttgatagtag cacctccaaa ggctgggaaa acagttcttt taaaaagcgt tgcaaatagc
    69541 atagctaaaa atcatccaaa tgttgaactt atagtactcc ttatagatga aagaccagag
    69601 gaagttactg atatgaaaga atctattgaa ggagacgtta tatattcaac ttttgaccaa
    69661 gtatcaagtc atcatgtcaa ggttgcagag atggtgttaa atagagctca aagattagtt
    69721 gaacatggta aagatgtagt aattttacta gatagtataa ctagattggc aagggcatat
    69781 aaccttacaa tatctcctac aggtagaact ttatctggag gtattgaccc tggtgcactt
    69841 catggaccta aaaagttctt tggtgcagca aggaatatta gacagggtgg ttctttgaca
    69901 atattaggaa cagcattggt tgaaactggt tctaggatgg atgatgtaat atttgaggaa
    69961 tttaaaggta caggaaatat ggagctacat ttagatagaa aattagcaga aaaaagaata
    70021 ttccctgcaa tagatattta caagtctggt acaagaagag atgatttatt gcttgatgat
    70081 gaagaaaaga ctgctctttg gagattaaga agagaaatga gtaataattc agtaatggaa
    70141 attacagata aagtcattga acttataaag agaactaagg acaataaaga gtttgtaaaa
    70201 tcaataaaga atttgtaaaa tcaataatac aaatgcaaat atggattata taaactaata
    70261 gaaaaatcac ttgaatggca taataagttg tgctataata atgtagttga taatgtaaaa
    70321 agaaagttaa tataattaat ttttttaaat aaagagaaga ggtgactata atgcaaaagg
    70381 aaatacaacc aaaatacaat ccagttgaag tgcgttgtgc ttgtgggaac acatttgttg
    70441 ctggttcaac taaggacgaa ataaaagttg aaatatgttc agagtgccat ccattctata
    70501 caggaaaaca aaagaacata gaaaaaggtg gaagaatcga caaattcaag aaaagattca
    70561 aaatggacta atttttataa aagtggagtt ggaggaagcc aactcctatt ttattacaaa
    70621 aaaacattca tattctactt taaattgtct ttttgtatta taataataaa tatgtaaaat
    70681 tgagtattct aaatacaata aaatgaggtg agtggatggc aaaacaagct gtaggtgggc
    70741 aagctgttat tgaaggtgta atgatgcagt caaaagacaa aagagcggta gctgttagaa
    70801 aaagtgacgg agaaatagca ctaaaagaag atagaataaa aagttgggta agagataaga
    70861 atatagataa gatacctttt gttagaggtt cttttgttat gatagataca atgattcaag
    70921 ggataaaaag tttaaacttt tcttcagagt tttttatgga agaagctgaa gaggataaat
    70981 ttgatttatt tataaagaaa atttttaaag ataaggcaaa tgatataatt ataatatttt
    71041 cattggtcat agcaatgtta ctttctgctg gattattcat ttttatacct acattggtag
    71101 gaggagcttt ttctaaagta atgcctaatg attttatgct taatttaata gaaggaatca
    71161 taaggatagc tatattattt gcatatatag tattgatttc acgaagtaag gatatagaaa
    71221 gagtctttca atatcatgga gcagaacata aatctatata ttgctatgaa aatgatttag
    71281 aacttacagt agagaatgct agaaaattta aaagattaca tcctagatgt ggtacaaatt
    71341 tcctatttat agttatggct gtatcaataa tattgtttgc attttttggt tggccaaatc
    71401 caattcttag aatatttatg agaattatat gtgtgcctat agtagcaggt ttatcttatg
    71461 aggtaattag agttcttggg aaatatgata atggatttac taaaattatt gcatatccag
    71521 gaatgatgtt gcaatatttt acaacaaaag agcctgatga tgagcaatta gaggttgctt
    71581 tggaagcatt gaaagcagta gtagattaga gaaaaggata tttgttatga cgataaaaga
    71641 tataattatt aaatattcag ataaactaaa agatataagt gatactccaa gattagatac
    71701 agagttattg ttacaaaaaa cattgggtgt tgatagatta tatattcact taaatctgaa
    71761 taaagagcta actgaagaac aaaaaacaaa atttatgggt tttgcagaag aaagattaaa
    71821 tggaagacca atagcatata tagttgaaaa tagggagttt atgggattag atttttttgt
    71881 taaggaaggc gtattgattc caagaccaga tacagaaact ttagtagaag aaataattga
    71941 aatatgtaga gaaaaaaaag atgtaagtat attagatata ggaactggtt ctggagctat
    72001 tacaataagt ttagcaaagt acattgaaaa ttctaaaatc atgtcttttg atatatcaga
    72061 gacagcatta gaaatagcta aaaaaaatgc tattataaat gaagttggtg aaaaaataaa
    72121 gtatattaat tctgatttat ttacagcaat aagtgatagt aacataaaat tcgatatcat
    72181 agtttcaaat ccaccatata ttaaaaaaca agatatagaa actctgcaca aacaagttaa
    72241 agattatgaa ccatataatg ctcttgaagg tggagaagat ggattagact tttatagaag
    72301 aataacagaa caaggtaaga aatatttaaa taagtgtgga atattagcat atgaagttgg
    72361 tcataatcaa gctgaagatg taataaatat tatgaaaagt aatggatata aaaaaatata
    72421 cacaaagaag gatattcaag gcattgatag agttgttata ggttacaata tatgatataa
    72481 tcaacaattg atatgttaca tttaatcgag gtgaaagtat gttaaaaaaa ttagaggtat
    72541 tggaagatac atataaagac ttaagtgaaa aaataggtga tccggatgta ataaatgatc
    72601 aaaaagtttg gcagaaatat ataaaagaac atgctgactt ggaacctatt gttatgaaat
    72661 acagagagta taaaagcgtt ttagatagta taaaagaatc aaaagaaatt ttacaagaag
    72721 agtcagatga agaattaaga gaattagcta aaatggagtt agctgagatg gaagaaaaag
    72781 tagcacctct ggaggaagaa ataaaaatac tattattgcc taaagaccct aatgatgata
    72841 agaacgttat agttgaaatt agaggtggag ctggaggaga tgaagcagct ctatttgcgg
    72901 gtgatttatt tagaatgtac tcaaggtatg ctgaaagaag aagatggaaa atagaattat
    72961 tgagtgcaag tgatactgga gttggtggat ataaagaagt atcttttatg ataaaaggta
    73021 aaggtgctta ttcaagatta aagtatgaat ctggagttca tagagttcaa agaataccat
    73081 caactgaatc tggtggaaga atacacacat caacttctac tgttgcagta ttaccagaag
    73141 ttgaagatgt agaggttgaa ataaatccaa atgatttaag aatagatgtt ttccgttctt
    73201 cgggtaatgg aggacaaagt gtcaatacta ctgactctgc tgttagggta acacatatac
    73261 ctacaggtga agtagtatct tgtcaagatg gaaaatcaca attaaaaaat aaagagcaag
    73321 ctttaaaaat attaaaagct agactttacg ataaagcatt ggcagaacaa cacaaagata
    73381 tagcagcaga aagaaaaagc caagtcggaa caggagacag gtcagaaaga ataagaacat
    73441 ataatttccc tcaaggtaga ataagtgacc atagaataaa tttaacttta tataagttag
    73501 atgcattttt agatggagat atagatgaaa tgatagatgc tttaattact gttgaccaaa
    73561 cagaaaaaat gactgcaata taagtaatgt tttaaagaag ctgtttcttc ctagaaatta
    73621 ttttctattt tgaaacagct attttgcatt ttaggtcatg ttatcatatt ctattgtata
    73681 taattgttat atacaagtat aggagggtta tatgatacta aaagtaacaa taattgggct
    73741 tttggcaggt gttataggga caggattagg aggagtaata tcagccattt ttaaaagaga
    73801 ggtcgataaa tatctaagtt tttttatggg attatctggt ggaataatgt tggctgtagt
    73861 ggtgtttgat ttaatgaaag aatccatgga caaaatgggg ataatcaata cagttatatt
    73921 tacgtttgtt ggagctctca taactatgta cataaaaaca aaattagatg tgtctggaaa
    73981 tatggcatct ggatatctta tattcataag tatattacta cataatttac cagaaggact
    74041 agccattggt tcttctttta tgtcaactga aagtttaggt attacacttg ctatagttat
    74101 aggtctacat aatataccag aagggttagc tatggcatta ggcttagttt gcaataaaat
    74161 gaaactaagt aaagttattt tgtttactgt aatagctgga ttacctatgg gtctaggaag
    74221 ttttttaggt gtttattttg gaggagtatt tacttctctt ataggagtat ttcttgctac
    74281 agcaggaggt actatgatgt atgttgtatt ggaagaaatt tttccacatt caaaaagtgt
    74341 gtattgtata attggtttct tgttaggtac aatgattgta aattatatat aaaattaaaa
    74401 tgaaagcagg catacaaaag atgaaaacta ttataagtaa tattgatata aataatattg
    74461 attatgagga aataaaaata caagcaaaac ttcttagaga aggtaaaaca gttatttttc
    74521 caactgagac agtatatggg ttgggtgcaa atgcattaga tgaaaatgca gtaaagaaga
    74581 tttatgaagc taaaggaaga cctagtgaca atccattgat agtccatata tatgaaaaag
    74641 aagaagtata tgacttagcc aaagatataa gtgataaagc taaacttgtt atagaaaagc
    74701 tttggccagg acctataaca attatattaa ataaaaaaga tataattcca tacaaaacta
    74761 gtggagggct tgatacagtt gcaataagga tgccttctaa tgttattgcc agggcaataa
    74821 taaaagaagc tggtatacct attgcagctc cttctgcaaa tatctcaggt cgcccatctc
    74881 caacaaaagc aaaacatgta tatgaagaga tgaatggaag agtggatgga atagttttag
    74941 gaggagacag taattttgga ttggagtcaa ctgtattgga tttaacagaa gagactccta
    75001 tgatactgag accaggaagt ataactaaag aagttttaga ggaacttctt ggagaagtaa
    75061 agcttgaccc atcattaagt aaaaaagaag ataatcaaaa agctaaagct cctggaatga
    75121 aatataaaca ttattctcca aatgcagatg tatatataat atctggaaaa agagaaaatg
    75181 tagcaacaaa gattaatgat atgataaaat ctaatagaga caaaggtcta aagacaggtg
    75241 taatgtgtat cagtagaaac cgagagtttt atgatggaga agtaatcgat ttaggaaact
    75301 ctcttgaaga agttgcaagt aatctgtttg atgctcttat agaaatggac aaaaagggcg
    75361 ttgatgtcat atattcagaa gagttcccta agactggagt tggacaagca attatgaata
    75421 gactactgaa gtcagcagga tacaaagtga taaaggctta agagggagtt gtaaaatatg
    75481 aatatactta ttgtgtgtac aggtaatact tgtagaagcc ctatggctga ggctatacta
    75541 aggaaagcaa ttaaagaatc tggaagaagt attgaagaat attcgatatc atcagcaggt
    75601 atatctacag caaatggaat gggtgcttct gaaaattcta tagaagtact aaaagaaatc
    75661 ggtatagact tatcaaatca tagaagtaaa gtaattacta aaaaattaat tgatgaatca
    75721 gatataatac taacaatgac taaatctcat aaagaaattt tagtacaagc agttccaaaa
    75781 tgcaaagaaa aagtgtatac ttttaaaggg tttgcaaata aaaatgagga agatatatct
    75841 gacccatttg gtggaaattt ggatatttat agaagcacta tgagagaaat aatgtattct
    75901 gtcaacgaaa tagtaaaaaa aatatgaaac ggaggataaa caaatgaaga taggattagg
    75961 ctgtgaccat ggaggatata atttaaaaaa agaaataata agctatttag aaagtaaagg
    76021 tatagaatgt gtagattatg gaactaataa tgctacagat tctgttgatt atcctgttta
    76081 tggagaaata gttgcaaatt cagttataaa taaagaagta gattatggaa tattatgttg
    76141 tggtacaggg ataggaatat ctttagctgc taataaggtt cctgggataa gatgtgcagt
    76201 tgtatcagat gtattttctg caaaaatgtc aaaagcacat aatgatgcaa atatgttatc
    76261 attaggcgaa agagttttag gaaaaggtct agcacttgag atagttgaag catggattaa
    76321 tacggatttt gaaggtgata gacatgctag aagagtaaac atgattaaat caatagaaga
    76381 aaaacataat aaataataaa aattacagtt ttatcaggag gaattatcaa aatgagcaaa
    76441 gtggtagaga caaaccatcc attaatacaa cataaattaa ctttaatgag agataaaaat
    76501 actggttcta aagactttag agagctttta actgaaattg caatgttaat ggggtatgaa
    76561 ataacaaaag atataccatt aaaagatgta gaaatagaaa ctcctattca aaaaacatca
    76621 tctaaagtag ttgcaggtaa aaaattagca ataattccaa ttttaagagc aggtcttgga
    76681 atggtagatg gattagtaag cttaatgcca gcagcaaaag ttggacatgt aggactatat
    76741 agagacccag aaacattaaa accagttgaa tattattgca agcttcctca agacatagga
    76801 gaaagagata taatagtagt tgaccctatg cttgcaacag ggggttctgc tgtagcagct
    76861 atagatttac ttaagtctaa aggagctaaa agtataaaat tagctaattt agtagctgca
    76921 ccagaaggta tagcagaagt gcaaaaatat catgatgatg ttgatatata tgttgcatca
    76981 gttgacgaaa gattaaatga acatggatat ataattcctg gtcttggtga tgctggagat
    77041 agattgtttg gaactaaata aaaataaata actataaata tttattaggg actttcttat
    77101 atagtgtata taattttatg taagaaggtt cttttttata tattttttct caaaatagga
    77161 attatgaatt gataaatttc tcgaattgag aataaaaagt ttttaccaat taaaaaagat
    77221 tgcttatttt acaaggtttt atagaatagt agtctatttt aatgtggcat gttagttgct
    77281 tacgattaag attataggta ttaagtgtat tagttaaatt gagaattgaa tattaataat
    77341 attattggga gtggtaatac atgaagaatt gtatagcagt aagaggggct ggagatttag
    77401 caacagcagt tattcataaa ttacacaaca gtggttttaa agtagttgcg ttagaaatag
    77461 aagagccatt agctataaga aggcaaattt ctttttgtga ggctgtttat gaaaaaaaag
    77521 taactgttga aggtgtagaa tgtatatttt gcaatactga aaaagaaata gaagaagttt
    77581 tatctcaaca taaagtagcc ttgattatag acccaaaagg agaaaaatta tctaagttaa
    77641 atccaatcgt tttggttgat ggaatactcg ctaagaaaaa cttaggtaca actaaagata
    77701 tggcaccact tacaatagct ttaggtcctg gattttgtgc aggagaagat gtagatgttg
    77761 ttatagagac aatgagaggt cataatctag gaagaataat aactaatggt agagcagaaa
    77821 aaaatacagg agtaccagga gcaataaaag gtttttctaa agagagagtt atgcattcac
    77881 agtatgatgg tataatggaa aatgtatgta agataggtga tatagttgaa aagggagacc
    77941 tactttgtta tattaataat tatgaaaaaa aacatgaagt tagagcaaca atatctggag
    78001 tccttagagg tttattaaag gatggagcaa aggtgaacaa aaatttaaaa atactagaca
    78061 tagaccctag aaaagaagaa gttaagaatg cttttacaat atcagataaa gctagatgta
    78121 tagctggagg ggttttagaa gccatactaa acaatgggat ttatccccaa aattaattta
    78181 tattagataa agctattaat attttattaa gatgatataa taaatttaat agattaaaga
    78241 gagcatatga cgggtattta aaatttaaat ggtaaaaatg ctcttttttt attggacatt
    78301 caattaacat gtgtatataa tataaaaata agtatttatt taggttgaaa tctaataaat
    78361 atataatacc agtacataag caaagaggag aaaagtaaat tatgagacca tcatgggatg
    78421 aatacttcat ggaaattgca gaagtagtga aaaagcgttc aacttgtatt agaagacaag
    78481 taggagctgt aattgtaaga gacaaacaaa tattaacaac tggatataat ggttctccga
    78541 gaaatcttga acactgtgaa aatattggat gtaagaggca ggaattaaat attccctcag
    78601 gagaaaggca tgaattatgc agagcattac atgctgaaca aaatgcgata atacaagctg
    78661 ctcataatgg tattagtgta gatggggcaa ctttgtatgt tactacaaga ccttgtgttt
    78721 tgtgtgcaaa aatgtgcata aatgcaggta tattgaaaat tgtttatgaa ggtgattatc
    78781 cagatgatat gtctacagaa ttattaaaag aagcaggaat agaactcata aaattttagt
    78841 ggataaaatt tatatgacaa taaatgtcaa attatgacac tgaaatacaa tggtatcaaa
    78901 tgattaaaag aaagtatttg aaaaatcatc agattagtag taagatatat tttataatta
    78961 aataaattta tgagatagat taattacatg ttatttattt tataataatg agggatacta
    79021 tttatgagta aaagaaatac acatacagaa attgcaaagt tgtttagttt aataagtcaa
    79081 ataggattga tgattgtaat atcaatatta ggatgtactt tcttaggaaa atttttagat
    79141 agtaaattga atactactcc agttctgaca ataatatttt tattgttggg tgttggaggt
    79201 gcttttagtg gtgtttataa aactctaata gtatatacac gaaggaagtg atatattgga
    79261 tataaaatta cttaaccagg taaggtcagt aacaaaaggt atagtaatat ttgatgtagt
    79321 tttaattgtg ctaatgttga taacatcaac attaagtaaa ccagtattat taggacttat
    79381 atttggctct ataatagcta tgttaaattt tagattattg gcgatatcac tggaaaaatc
    79441 agtgacattt cctgctggga aggcacaagc ttatgcatca gcacaatatg ctattagatt
    79501 atttataatg gcagttgttc taattgcatc agctacagta ccacatttaa atataatcgg
    79561 aacagcattg ggattattga gcacaaagtt tgtcatatta tcaaaaaact ttataaataa
    79621 attaaagagg aaggaggcat aagtatgaat caagcgcatt attatctcat aggaaacttt
    79681 aagattagtg aaacaatact agtaagttgg ggaataatgg cctttttagc gatagcatct
    79741 tattttttga ctagaaactt aaaaaaagtt ccaactagta aagttcaaat attcttagaa
    79801 tttgcagtag gtggtcttgc taaaatggtt acagatgtta tgggtaaaaa tacagtaaaa
    79861 agaatgccat atatgatacc atacatagga agcttgtttt tatttttcgc atgttcaaat
    79921 ttaagcccat tacttggatt aaggtcacca acaaccgact tagacacaac tgctgcatgg
    79981 gcaatgatta cattttttat gatttatttt gcaggagtta aatttaaggg gttatcatac
    80041 tttaaagaat tggctcaacc acttgccata atgttaccaa tcaatattat aggtgagtta
    80101 gctagaccaa tatcattaag tttccgtcca tttgggaata ttttaggtgg aacaataata
    80161 atgggtctgt tttatcaact tttaggtttt atatctagtt taataccagg attatcaata
    80221 ccaattggag aaatattaat accagtccca ttacacttgt actttgactt atttgcagga
    80281 ttgttacaag catatatatt tataatgtta acaatggtat ttatatcaag tgcaggagag
    80341 ttagattaag aaatcaactt atattaagat aaaaataaaa taatttaaaa aattaaagtt
    80401 ttaaggagga aataattatg gaaacagcaa tagtagcggc agcatcagca ataggagcag
    80461 ggatagcagt tgcaacaggt ataggtgcag gtataggtca aggtatagca gcagctaaag
    80521 ctgcagaagc agtaggaaac caaccagaag ctaaaggtga tataacatca actttattac
    80581 taggagttgc tatagcagag tcttcagcaa tatatggttt ggttatatca ataatacttc
    80641 tattcgtaaa tccattcttt aaatacttag gaatgtagat ttagtcctta aatattttga
    80701 gataggttta taggtaaatc atctcaaact tataatcatg agatgaactt tatcatctcg
    80761 tgattataag tagttatgat ttatggaaag gaggataatt atggaaaaag cactagtagg
    80821 tataacgtgg gaatttgtgt tccaaattgt taatactttt ataatatttt tacttctgag
    80881 aaagctttta ttcaagccag tattaaatat aattgaatca agagaaaatg atattaaaag
    80941 tgatttggca gaaggcgaaa aagcaaaaaa tgaaggttta gctctgaaaa aagaatatga
    81001 gtcaaaaatc aattttgcca aggatgaagg tcaagaaatc ataaaacaag caactataag
    81061 agcagagcag aaatcagatg atatagtaaa tactgcaaag aaagatgctc ttgatataaa
    81121 agaaaaagca aacaaagata tagaacaaga aagacaaaag gttataaatg aaatcaaaaa
    81181 tgatatatct aacatagcac tacttgcagc atctaaagtt attgaaaaag atttagataa
    81241 atctaaacat gaagaattga tagaaaactt tataaaagag gtaggggaag ctaaatgata
    81301 aatgtaatag caaatagata tgccgaagcc ctatttcaat taggagaaga agaaaattca
    81361 actgatgtct tattcaaaga actagaaaaa gtagtagata tgatgactaa agttagtaaa
    81421 gatttctaca aagttttaaa atcaccatta gtttcaaaat cagaaaagaa aaacttggta
    81481 gaaattattt ttagtaagga agtaagttct aacataaaaa actttttaaa agttttagta
    81541 gataaagata gaatatcata tttagaagat atcgaattag cttataaaga attattaaat
    81601 aagaaaaaca atgtaattga tggagtagca ataagtgcta ttccaatgag tgaaacagat
    81661 attaaagaac ttgaagtcaa actttcaaat aaatacaaca aaaatgttac tatagaaaat
    81721 gttgttgaca agactatact agggggagtt ctagttagaa ttggaaatga acaaatagat
    81781 ggcactgtga aaactcgtct tgataagatg aaagaaaagc tatctgaagt aatatcttaa
    81841 gaatggcggt gaacccatga acttaaaacc tgaagaaata agttctataa ttaaacagca
    81901 aataaaaaat tatgagaata aagttgagtt gacagataca ggtagtgttt taacagttgg
    81961 ggatggtata gcgagtgtat atggattaga aaaagctatg tctggtgagt tgctagagtt
    82021 cccaggtgaa atatatggta tggcacttaa cttggaagaa gaagtagttg gagctgttat
    82081 ccttggagat gacagtgaaa taaaagaagg cgatatagtt aagagaactg gaagaatagt
    82141 tgaagttcca gttggagaag ctttaatagg tagagttgta aactcactag gtcagccaat
    82201 agatggaaaa ggacctatag cgtacacaaa aactagacca gttgaatctg aggcacctgg
    82261 tataatagat agaaggtctg tttatgaacc attacaaaca ggaatcaaat caatagattc
    82321 aatgatacca attggtagag gtcaaagaga gttaataata ggtgacagac aaactggtaa
    82381 aacatctata gttattgaca ctatactaaa tcaaaaagga aaagatgtta tctgtatata
    82441 tgtagcaatt ggacaaaaac gttctactat agctcaatta gttagctctt tagaaaaagg
    82501 tggagctttg gattatacaa tagtagtttc agcaacagca tctgaatcag caccacttca
    82561 atatatagca ccatatgctg gagcagctat gggtgaagaa tttatgtaca atgggaaaca
    82621 tgtacttata gtgtatgatg atttaagtaa acaagctgtt gcatatagag aaatgtcatt
    82681 gttacttaga agaccaccag gacgtgaggc atatcctgga gatgtattct atttacattc
    82741 aagattactt gaaagagcag ctaagttatc tgatgaattg ggtggaggtt caatgactgc
    82801 cttgcctata atagaaactc aagctggtga cgtttctgca tatataccaa caaatgttat
    82861 atctataaca gatggtcaaa tatacttaca accagagtta ttctattcag gtgtaagacc
    82921 agcagttgac cctggtatat cagtatcaag ggttggtggt tctgcgcaaa ttaaagcaat
    82981 gaaaaaagtt gcaggaacat taaaacttgc atattcacaa tatagagaac ttgcagcatt
    83041 ctcacagttt ggttctgact tagatgaaga tactaaaaag agacttgctc aaggtgaaag
    83101 aatcgttgag atattaaaac aaggtgagca tcaaccaata aaagttgaaa atcaagttat
    83161 gataatatat gctgttataa ataatcattt agaggatatt ccgatagata atatagctag
    83221 atttgaatca gaattgtatg catttgtaga taataattat ccggaaatat caagaaaaat
    83281 attaggtgga gaagacttca ctcatgattt aacagatgca ataaatgaat ttaaagaaaa
    83341 gtttgttgtt gaagtataat cctttttaaa aaaggaggta aattaattgg caggagctgg
    83401 aatcaaagca atcaaaacac gtatgggaac tgttgaaagt acaaagcaaa taactaaagc
    83461 aatggaatta gttgcatctt ctaagcttag aaaagcaaaa gaaaaggctg aagattcaag
    83521 agaatatttt aatactttat acaatacagt aaaagatatt gcccaaacaa cacgtggaat
    83581 tagaaatgaa tttttaaaag aaagagaagt aaaaaataaa tgttatgtag tagtagctgg
    83641 agacagagga cttgcaggtg gatacaattc caatgtatta aaggaatctg tctctcatat
    83701 gaaaggtaaa aaggaaacag tgattactgt tggaaagaaa gcacatgaat ttttttctaa
    83761 aagaaactac aatatagcaa aagatataaa tagtgttgaa gcttgtggat atgaagatgc
    83821 gacagaaatt tcacaaacta ttattgacct gtataaaaaa ggtgaagtag atgaagttta
    83881 tattgcttat acaaaattta aatctgcttt atcacaagaa gttgaaattt tgaaattgct
    83941 tccattagtc tttgaaaaag atacagacga acaaggaatg gcagtaaaag aagaaaaaca
    84001 aaatagatca aaagtacaat atataccatc agcagaagca gttttaagtt atattgtacc
    84061 tcagtttata tcaggtacag tatatggtgg aattttggaa tcttttgcat cagagcaagg
    84121 tgctagaaga actgcaatgg aatcagccac agacaatgcg aatgaaatgc tatctaattt
    84181 agagttaagt tataacagag caagacagtc agctgtaact caagaaataa cagagatagt
    84241 tggtggagtt gaagctctaa aatagggagg ttaggaaatg gcaaatgtag gtaaagtagt
    84301 acagattgta ggagctgtac tagatgttaa gtttgatagt gaacaaagcc tacctaactt
    84361 attaaatgcg ttagtaataa agttaggaga taaagaaata gttgcagaag ttgctcaaca
    84421 tataggtgat gatactgtaa gatgtatagc tatgagtgca acggacggac ttgtaagagg
    84481 tatggaagtt gtagatacag gagggccaat aagtgtccct gttggagatg agactttagg
    84541 tagaatattc aatgttcttg gaaaaccagt tgatgggaaa ccagctccaa aatctgcacc
    84601 taaattacct atacatagac cagcaccggc gtatgatgaa ctagaaacta cagcagagat
    84661 actagaaact ggtattaagg tagttgactt actagctcca tatctaaaag gtggaaaaat
    84721 aggtctattt ggaggagcag gagtaggaaa gacagttcta atacaagagc ttataaacaa
    84781 tattgctaag caacatggtg gtatttctgt attttcagga gtaggagaaa gaacaagaga
    84841 aggtaacgac ctttatggcg aaatgagtga gtctggagtt ataaataaaa cagctctagt
    84901 atttggtcaa atgaatgaac cacctggagc gagaatgaga gttgctttaa ctggacttac
    84961 aatggcagaa cattttagag atgagcaagg acaagacgtt ttacttttcg ttgataatat
    85021 attccgtttc acacaagctg gttcagaagt ttcagcactt ctaggacgta tgccatcagc
    85081 tgttggttat cagccaacat tagctactga aatgggtgca cttcaagaga gaataacatc
    85141 aactaagaaa ggttcaataa catctgttca agcagtatat gtaccagcag atgacttaac
    85201 tgacccagca ccagctacaa cattctctca cttagatgca aaaacagttt tatcaagaca
    85261 aatatcatca ctgggtatat atccagcagt tgaccctctt gaatctacat caaggattct
    85321 tgaccctagt atagtaggaa aagaacatta tgaagtagct agaggtgtac aatcaatact
    85381 tcaaagatat aaagaacttc aagatataat tgctatactt ggtatggatg aattatctga
    85441 tgaagataag ttaatagttg cacgtgctag aaagatacaa agattcttat ctcaatcatt
    85501 cacagttgct gagcaattta caggaaatcc aggtcaatat gttcctgtta aagagactgt
    85561 aagaggattt aaagaaattc ttgaagggaa acatgatgac ttaccagagt cagcattctt
    85621 atttgtagga acaatagaag acgctgttag aaaagcgaag ggaagtatgt agtcatggcc
    85681 agtgaatttt cattgaaagt tgtaactcca agtaatactt tttatgatgg agatgttgaa
    85741 atgatagtag ttagaactac aaaaggagac aaaggggtgt tgaaaggtca tataccattt
    85801 gtttcaggta tacctgtagg aactttaaag ataaaaaaag agggaagttt taaagaggcg
    85861 aaaatagcag aaggattcat taatgtaact caagataaaa ctgtcatatt gacagaatct
    85921 gctgagtgga tttaataaat taatttagag tataaaaagt cattttgacc aaaaaaactt
    85981 ttgggtaaaa tggctttttt gtgttttggt gttaataaaa taacgataaa attgtaagtt
    86041 tttagtgata ataaattcac aaaatgttta aatttactgc caaattatgt tgtaattaat
    86101 aagataaaga agatttagat agcttttatg taagtgaaaa agtcttcata taagaaatac
    86161 atataaaatt tttataaaat ttaaaaaatt tgcttagttg tgtagtataa taaataatat
    86221 aatagatttg tatataatat tcattacaaa taattttaaa agttacagtt ttattataat
    86281 gattattaaa ttaagataag taacataaac taaataataa tgtgtattat cgatagtaaa
    86341 tttataaatt cattattaat tattgaaaga agtattataa attttctgga ggaacaatga
    86401 atatatttga tattggcgta gatataattg aaattgatag aataagaaag gctgtagaca
    86461 aaaataatag gtttttggag aagatattta cagatagaga aatagagtat tttaattcta
    86521 agaattttaa agcagaaagt atagcaggta atttcgcagc caaggaagct ataagtaaat
    86581 ctataggtac aggaattaga ttgtttaatt ttaaagatat agaagttctc agaaatgaaa
    86641 tgggaaaacc aatagtaaaa acttataata atctagcaaa aatgtgcata gattataatg
    86701 ttttagaaat aaaagtttca atatcacatt caaaagatta tgctatagca aatgcgataa
    86761 ccataattaa ggactaagga gtgattacat tatgatggat aaaacagcaa aagaaataat
    86821 gacaacagat gtaatagtag caaaacaaga tgatagtata gcagatgtag ctaatatgct
    86881 aattgcagaa aaaataggag gtctgccagt tgtagattca gagaatagag ttgttggaat
    86941 aatttctgaa acagatattc ttaaaaaaga aaaatatata gaagcacctc tctatataaa
    87001 tctattacaa ggattgattt tcttagatga cttaaaaaaa gttgaaaaag atataaaaca
    87061 agtagctgct tataaggttg gagaacttat gtctaaagat ataataaagg ttcatgaaga
    87121 tgataagttt gatgatgtag ctaatgtaat gattaaaaaa tcaataaaca gagttcctgt
    87181 agtagatgat gacaacaaac ttaaaggtat aatttgtaga tatgatataa taaaagcttt
    87241 atacaatgaa taaactgaag taggaggtgt gatgtgagaa aaaagtggac catagtatgt
    87301 attatgttct tggcactggt tataattgta ataggatgcc aaaaacgaca gtccacaaaa
    87361 gaagaagtat acaaagattt tcaaaagcag atttctgata tgaattatta cagttgtaaa
    87421 gctgaagtag aagtagttgg aaataaaagc ccacacaatt atgttttaat tcatacttat
    87481 aaaaaaaccg ataactataa attagaagta atttccccaa aacatttaaa agggaaaagt
    87541 atagaatatc aaggtgataa aatattagtt aaaaatccaa agattagtga tgtagtggag
    87601 ttacctaata caggaaaaaa taatcaatat ctttttgtag gagactttat aaaaaactat
    87661 cttcaaaatg aggagatgaa agtaaagtta tccaaaggac atttggtttt agagactttt
    87721 attcctgggg ataataaata ttttaacaag caagtattat atgtaaatgc tgacacaaaa
    87781 aatcctgaaa aaatggaagt gttagataaa gagggagtgc caagatttac agtaaaatac
    87841 aaagattttg aatacagaaa ctaaggggga ctaaagacat gcaaaaaata acagtgccta
    87901 catgggcaga gataaatcta gataacttaa gatttaactt aaataatatt aaaaatttat
    87961 tagaagaaga tattaagatt tgtggagtaa taaaagctga tgcatatgga catggtgcag
    88021 tagaagttgc aaaattgcta gaaaaagaaa aagtagatta cttagcagta gcaagaactg
    88081 ctgaaggaat tgaacttaga caaaatggca taacacttcc tattttgaac ttgggatata
    88141 ctccagacga agcttttgaa gattctataa aaaataaaat aactatgaca gtttattctt
    88201 tagaaacagc acaaaagata aatgaaattg caaaatcttt aggagaaaaa gcctgtgttc
    88261 atgttaaaat agactcaggg atgactagaa taggtttcca acctaatgag gagtcagtac
    88321 aggaaataat agaattaaat aaattagaat atatcgattt agaaggtatg tttactcatt
    88381 ttgctacagc tgatgaagta agtaaagagt acacttataa acaagctaat aattataaat
    88441 ttatgtctga taaattagat gaggctggtg taaaaatagc tataaaacat gtatcaaaca
    88501 gtgcagctat tatggattgc cctgatttaa gattaaatat ggtaagagca ggaataatat
    88561 tatatggtca ttatccatct gatgatgtat ttaaagatag attagaatta agaccagcca
    88621 tgaaattaaa atcaaaaatc ggacatataa aacaagttga accaggtgta ggaataagtt
    88681 atggactaaa atacacaact acaggtaaag aaacaatagc tacagttcca ataggatacg
    88741 cagatggatt tactagaatc caaaaaaatc caaaggttct tattaaggga gaagtgtttg
    88801 atgtagttgg tagaatatgt atggatcaaa taatggttag aattgacaaa gatatagaca
    88861 taaaagttgg agatgaggtt atactatttg gagaaggcga agttacagct gagcgtatag
    88921 ctaaagactt aggaactata aactatgaag tgttatgtat gatatcaaga agagttgacc
    88981 gtgtttatat ggaaaataat gagcttgtac aaataaacag ttatttgcta aaataaaacc
    89041 atgatattat aatctgggag gcgattttgt gtacgataag agtaaagaaa aaatagaagt
    89101 tactttacct gactctctga tttctgaagt tgatagtata gttcagatgg agaacagtaa
    89161 cagagaagat tttgcaaaag ctgcttttca gttctatata actcagaaaa agaaaattca
    89221 tattaaagaa tctatgaaaa cgggttatag agaaatgggt caaattaatc tgtcactagc
    89281 tgaattaggt atgacagttg aagaagtatc ttctgatgat aaaaatgaag ggaagattgc
    89341 ccaaggtgag tactaattgt gaaataaagc gtggtgattt atattacgct gatttaagtc
    89401 cagttgttgg ttcagagcag ggaggcgtta gacctgttct gataatacaa aatgatgtag
    89461 gtaataaata tagtcctaca gttatagtat cagctataac atctcagatt aataaagcca
    89521 aattacctac tcatgtagag ataagttcca atgaatatgg gcttaataaa gactcagtaa
    89581 ttcttttaga gcaaattaga actatcgata aaaagagact gagggaaaaa attggttgtc
    89641 tagatgaaaa tatgatgata aaagtagatg atggacttca aataagttta ggattgttta
    89701 ctttttaaag agggatttgt cttttattag acaatccctt ttttctttta aatatctctt
    89761 aaggtttaat tttaatgtac tatgttaata aaattaaaaa taacgcaaaa aaatagcata
    89821 aaagtgatat aataatatgg aattgatata aaattacgaa ctcaagggag gtaattgcat
    89881 gagagaccat aaaggattaa atgagattgc gcgtatcata agaagagata tagtttcaat
    89941 gatacataga gccaaatctg gacatccagg agggtcatta tcagtagttg aaatacttac
    90001 tgcgttatac tttgatgaaa tgaatgtgga ttcttcaaat cctaaaatgg aggatagaga
    90061 tagatttgta ttatcaaaag gacatgctgc accagcatta tatgctacat tggctgaaaa
    90121 aggctatttt gataaggaag aactgaatgg attaaggaag ataggaagga tgttacaagg
    90181 tcatccagac atgaaaggca cgccaggtgt ggaaatatct actggttctt taggtcaagg
    90241 tttttcagta gcatgtggta tggctatggc atcaaagttg gataatgctc cgtggaatgt
    90301 gtatactttg cttggtgatg gtgaggttca agaaggaatt gtttgggaag ctgctatgag
    90361 tgctgcacat tataaacttg ataatttaat tgctttttta gataataatg gacttcaaat
    90421 agatggagat atagaaagcg taatgagttt aggttcaata gttgataaat ttaaagcttt
    90481 tggttggaat gtaattgaga tagatggaca tgattttgac caaatatttg cggctcttga
    90541 tatagctaaa tcaacagtta aaaaacctac aatgatagtt gcaaaaacta taaaaggcaa
    90601 aggaatatct tttatggaaa atcaagcagg atggcatggg acagctccaa gtgatgagga
    90661 gctagaaaaa gccttgcttg aattaggagg tgctgacaat gagtaaaatg gcgacgagag
    90721 aagcatatgg taaagcatta gtaaaattag gtcaaataaa tgacaatgtt gtagtattag
    90781 atgcagattt atcaaagtct acaaaaacac atgattttta caagtcattt ccagatagat
    90841 tttttaatat gggtatagct gaacaaaatt taataggcgc tgcttgtgga ttatcaactg
    90901 ctggtaaaat accttttgca agtacttttg ctatgtttgc tacgggaagg gcttttgaga
    90961 ttataagaaa ttcagtttgt tatccaaagc taaatgtaaa aatatgtgct actcatgcag
    91021 gtcttactgt tggagaggat ggagcatctc atgaaagtgt ggaagatatt gctataatga
    91081 gagctatacc aaatatgaca gttcttgttc cagctgatgg agttgaaaca gaaaaaatta
    91141 tttttgaaat agctaagtat aatggacctg tttatgttag attagggaga agttcagtac
    91201 cagttttatt tgatgaagat tataaatttg aaataggaaa aggtacagtc ttaagagaag
    91261 gaaaggatgt atcaattata gcttgtggaa ttatggtaaa tgaagctcta ttagcacaag
    91321 aaaagttgca agaagaaggt ataaatgcta gagttataaa catgtcctcg ataaaaccta
    91381 tagacaaaga tttaatatta gaatcagcaa aagaaacgaa tgctattgta actgtagaag
    91441 aacatagcat aattggggga ttaggttctg ctgtaagtga ggtagtagga gagtcttgtc
    91501 caaccattgt aaagaaagtt ggaattaaag atacatttgg agaatctggt actccaaatg
    91561 aattgttaaa aaaatatgaa ttaacttgtg atgacataat aaagactgtt aaagaagcta
    91621 ttattgcaaa aagaatgtaa gagatataaa ttattcatgt ttgttaataa tataatatat
    91681 ttaaaagaga ggtataaagt gttatattaa tttatatctc tctttttttt atatgatatc
    91741 aatatatcaa aaatgtaata aaatattcaa atttttacaa aaatagagaa aatattcaaa
    91801 tatatattga ctattcagaa aaatatgact aatatataat ctatagagaa actaatttta
    91861 tatataatga ctacttagat aaaagaatct aaaaaaatta tgagaggagg agtagggtat
    91921 aaaatcagat tataagtttt aagttattat actaaaaagc tataaaacag ttatcatgta
    91981 ttttatgtta aaggaaattg taggtagttt atcgaattat ttaatcagaa gaaaaaattt
    92041 cacatgggga ggtaactgag atatgtcaga aaaagtaaat gttaaaacag tcatcagttt
    92101 cgcaggtgcg tatgtagcaa cagtaatcgg ttctggattt gcaacaggac aggaaataat
    92161 gcaattcttc tctttttatg gttttgcagg tattattggt gggataattt caatggtatt
    92221 attctcatgg atgggtgctt cagttatgtc aaaaggtaaa gagcttcaac ttaaagaacc
    92281 tatcaaaatt tatcgtgttt attgtggtaa gtatttaggg atattctttg aatggtttgg
    92341 acctttattc ttatttggtg ttttcgtagt aatgatttca ggagcaggag caactttaac
    92401 tgaatactat ggattaaatc catttgtagg tagagtaggt atggcagtag tagcattatt
    92461 aactgtttca ctaggtcttg ataaattatc aaagatacta ggtggaatag ggcctataat
    92521 aataatcttt acacttttag ttggtggtat aagtttagct aaaaacatag gtaatatagg
    92581 agaagctgca caagttctta gcactgtaaa gatagctaaa ccagttccaa atgcctatct
    92641 atctggtgta atatatacta cttataacac aattgttgtt atggcattct taactggatt
    92701 aggagcaagt gctgctaaca aaaaagaagc tatttgtggt ggtatattag gtggagtagc
    92761 acttatggct gcagctataa tgatgcactt agctattctt tctgatatag gaaacttata
    92821 ttcaaaagca ataccatcat tattcttagc agataagatt tcaccagtaa ttggagtttt
    92881 attctcaata attcttatat taggtatata tacaacagct gtacctttat tatggtcagt
    92941 aactaataga tttgtagatg ataaacatcc taagtttaaa ttaataactt taatagcagc
    93001 tatattaggt cttataggtg gcttcctacc atttgataag ctggttggta ttttatatcc
    93061 atatactgga tatatgggcg tcataatact ggtttgtgtt ctttatagac agattacaaa
    93121 aacatctgga tatcaagaag gaatcagtga caaataagta ttttttaata ttgtaaactc
    93181 aagagctata tgaaaacaat gaaaatgttt tcatatagct ctttttattt tttagctcgt
    93241 ttattatgaa ataggaaaaa catgtttttt agttacatta catatattta taattatgga
    93301 taaatatata ctaatcaata atttagagtc taagataagc ttataaatca tatatttaga
    93361 atatatggga ggagtgataa gattgaatgt aaaatttaat attaaaggta taatttatgg
    93421 agttatagct cttgtattcg ttataggggg atttatattc ataccaagta tgtttgtaga
    93481 gaaatctaaa cccatagatt atacagtatt acaaagaaat tcaataccag aaaagatatt
    93541 agatgtgatg gataagtata caaatgaaga aagagcatta gcggctaaaa tcgataacaa
    93601 aatatacatt atagtgacta gaggaaataa taaatatggt atagaaatgg acaaaataga
    93661 aagtgtggtt gaggaaggaa aggatgtttt gagagtcaag ataaagtata aagataagga
    93721 agattctttt ccatacatag ttgttgaaac aaatatgagt gaacttccag atagaataga
    93781 attaaatgcg acgaaataag aaggtatttt ataattaaat aactgcatat tgtacaataa
    93841 agtcatggtt tttattaatg taagtaaatt gtatatggtt cttattgttg taaaagccat
    93901 gacttaaaat gcttataaag taagatatta acagtagtat ttattactat attaaatggg
    93961 gtctggaaat acttaatgtt ctaattattt ggagtgataa ttctagtttc agtaactatg
    94021 tagtctaatt gtgcatcatg agtttctttt ggaatagaat cgaatatctg gaagtcaaat
    94081 gctatgccaa tagttatagc atcttttctt aagttttcta aaaatctatc ataaaatcct
    94141 ccaccatatc ctaatctata gcaatgtata tcatatgcta cagctggtac aattacaaca
    94201 tctaaggcct taatatcaat tgtaggtgat ttttcgttag gttctcttat tccatatgct
    94261 ccaattctca atccctcttt taaatctgtt atttgagtag ggattaatgt atgattttct
    94321 tttattgtga tgggacttga tactattttc tttagagaca aaagtttttt gattaaatta
    94381 tctgtttgaa cttcattgtt aaaatttaga taaagcatta tattagttgc atttcttata
    94441 tcttccattt gaagtaattt ttcagttatt aaatttgaat tactaagtac aaagtttgca
    94501 ctcttatttt ttcttgattc aataactttt tttctaaatt cttttttcat aaaataattc
    94561 ctcccttaat atgttataat gtgtacagca attgtattta atataaattt tagtataatt
    94621 tattgtaata aagcaatata tttgggtaaa tgtaataaaa ataacagcta gtcatataat
    94681 aataatagtt tatgtaaaag gagatgtatc ttgtgatttc aaagaagaaa gctatttttt
    94741 taggggtgat tttagtaatt ataacagcta tggttacatc agcatttcag ttgacattgg
    94801 ggaataaagt tgtaatatcg aaagaactct atgaagacta taaaaaatat gataagttgt
    94861 taggactaga atctattata aaacaagatt tttataaaaa agtatcagat actgatttgg
    94921 taaatggagc agcaaaaggt ctatttctag gaacaaatga taagtattct ggttattata
    94981 ctaaagatga aatggagaat ctaattaatg atagtgaagg ttcttatgtt ggtgtaggta
    95041 tgtatatagg ggcatcaaaa gatggtggct tagtagtagt tcccatgaaa gattctccag
    95101 cagagaaagc aggtgtaaaa tcaggggata aattagtaaa agtcaatgga aaatctgtct
    95161 catataaaaa ttcagatgaa gctgttcgta tgatgaaggg taaaaaaggg aaaacagttg
    95221 aactgactat attaagagaa gataaacaat tgaactttaa agtaaaaaca gaccagataa
    95281 ttgagaagag tatagaaagt aaagtaattg ataatgattt aggatatata gaaattaccc
    95341 aatttatatc aagtacatat actgactttg ataaagcttt aaaagaatta aaagcaaaaa
    95401 atatcaaggg attagtaata gaccttagaa ataatcctgg tggaatgcta gatatatgta
    95461 aagaagttgc tgatgagtta attggtgaag gaactatagt atatacaaaa gataataagg
    95521 gaaatactga gtacttgaaa tctgataaag aaaaattggg acttccaata gtagtgttaa
    95581 ctaatggaga aagtgcttct gctgctgaaa tattaacagc tgcaatcgtt gataataaag
    95641 aaggtatttc tgtagggact acaacttttg gtaaagggtt ggtacaatca gttgtaagat
    95701 tgaaggatgg aacaggatac aagttaacta ctgctcaata ttttacacct aatggagatt
    95761 atatcaatga aaaaggcata aagcctacta ttgaagaaaa agatgaaaat aaacagttag
    95821 atgtagcgac taaatggctt agagaacaga ttgataaata aagtttaatt tttataaact
    95881 tatattgtaa aataaagaac cttaataaaa ggagtgtctc aaaattaact ttttagttta
    95941 tgaggcactc ttttgtgggt ctttaaaata aagtgtgtat tcttctaaaa agtagtgata
    96001 attaaaatat taaatatcac tatatataag gaaggtgcac actttttatg tttaacaaaa
    96061 acgaaatatt aaaaaaactt attgaagaat atgatgttaa aacaactaca gatattcaag
    96121 atatgctaaa agatttattt gcaagtacaa ttcatcaaat gttagaagcg gagcttgacg
    96181 accatttagg ttatgataga tatgacaata agaataaaaa tactaaaaac tctagaaata
    96241 gatatagaaa taaaaatgtt aaatcagatt ttggagaaat aactttaaat attccaagag
    96301 atcgaaatgg agattttgaa ccaaaggtaa ttagaaatta tgaaaatgat atatcaggaa
    96361 tagagaacca agtgattgga atgtactcaa aaggtatgtc tactcgagat atatcaagcc
    96421 accttaagag tatttacgga attgatatat ctcattctct aatagctaaa attactgata
    96481 gagttctacc tttagctcat gaatggcaaa gcagagctct tgatatggtt tatccaattg
    96541 tatttatggg tgctatacat tataaagtta gaagtgaagg tagaataata aacaaagctg
    96601 catatatagc cataggtgtt aacttagaag gtataa
//
LOCUS       DAMJYN010000004        85173 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.004, whole genome shotgun sequence.
ACCESSION   DAMJYN010000004 DAMJYN010000000
VERSION     DAMJYN010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 85173)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 85173)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..85173
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.004"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            404..895
                     /locus_tag="PC466_000338"
     CDS             404..895
                     /locus_tag="PC466_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbM family protein"
                     /protein_id="HDF2767774.1"
                     /translation="MGMIGCYTKISEENVFKLQQAEENLQDFVFEDANENSTINIDKA
                     WHAIHFTLTGCPFGGDDENIFSKLVLSGNILMEIDGEFPVMLITANDVKKLSKAMNSL
                     EEQAFRKRFNINEMLENNIYPVMNDESEDDFFEYVWANLIELKKFIQEASDDGLAVIF
                     FIM"
     gene            1425..2297
                     /locus_tag="PC466_000339"
     CDS             1425..2297
                     /locus_tag="PC466_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2767775.1"
                     /translation="MEMKIAVSNLSKRFGKKQALDNINLEIDSGMFGLLGRNGAGKTT
                     FMRILATLLSKTEGSIHMCGVPIENTKEIRNMVGYLPQDFSMYPNMTVYKAMDYLAVL
                     SDIPLRKRRKIIAKLLSKVNLTNYQNVKVKSLSGGMNRRLGIAQALIHNPRVLIVDEP
                     TAGLDPEERIRFRNLLCEIANDRIVILSTHIVGDIEATCENVAILDSGKVIYNGSTEA
                     LAKLAEGKVYSIEVDKKDIENIKSRFIVIGMLTHGGKAILRIISDDKPFETAVNCNPT
                     IEDGYMLIMGGDNI"
     gene            2294..3583
                     /locus_tag="PC466_000340"
     CDS             2294..3583
                     /locus_tag="PC466_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2767776.1"
                     /translation="MNLFIKECKNILKSMVYYIFIVVLVFFYISQLGSSVSNDVSKNI
                     PNDGNPLVAPQKVENIDEYYSVHNQYPYGQKESMKTEKVIPNATINLIREYQKNTYTT
                     YPTGVVKYIKLDQNKTKTIEKYIEEITGKSISEINLIWKTDESIKIDYSKVSLERFEE
                     IMQRVDDILGGGSAYAFDKLQRFGVVPVTYDEAMKNYNYTIQKDKVSNGYARIFCDYI
                     GIVLSIFPVFVAVFMSLKDKRSRMREIIYSKQVSSCKIVLSRYFALVFIMILPVLILG
                     MKDLLPLIFFAKDKGISIDNLAFIKYTLWWILPTLMIVTAVGMSITILTDTPVAIIVQ
                     LIWWLYSINSTGLKGDYSTMGLMIRHNSVLNGDIIIQNFNQIMINRIVISLGALVLVL
                     LAIFLYEQKRRGNLDVWAKFSKLFSSNKRKLQIKHFN"
     gene            3513..4157
                     /locus_tag="PC466_000341"
     CDS             3513..4157
                     /locus_tag="PC466_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2767777.1"
                     /translation="MFGQSFQNCLVLIKENFKLSTLTNLICSIILLCMIPLIQGVANL
                     DRISTAICLENYVAIIGIVMLVPVFSLEQSKEIDEIVSSKSLSQVIVQLIRILMSIIG
                     IVVLIIGFVNVLIYLGCNFPVVEYIIGSFASAMFIGSLGMFFSNLFNNTIIGYMISIG
                     YLILNMMTKGKYVGKFFIMSMSQGSFDEKYWLILGSVVLIIASLLIKPIKRKIR"
     gene            complement(4424..4888)
                     /locus_tag="PC466_000342"
     CDS             complement(4424..4888)
                     /locus_tag="PC466_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2767778.1"
                     /translation="MNLNKVKFTEEHAIEVTNWKYEGKYSIYNLPPWEEIKKKNFSLS
                     KEDKRKNFISFINDNKELIGFINLLDEGSYVFFGIGIKPDYCGMGIGKEIISLGLQEC
                     RNKYSTKPIVLNVRTWNMRAVKCYKSQGFKIVETQVQKTHLGDGEFFVMRYQ"
     gene            complement(5905..6732)
                     /locus_tag="PC466_000343"
     CDS             complement(5905..6732)
                     /locus_tag="PC466_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AIM24 family protein"
                     /protein_id="HDF2767779.1"
                     /translation="MDLSKKVKILENASDGKSEFEILEFEKLEGASSPLMAMGLYFAR
                     EAGLKARQIKIKLNNSSIKTEAGALYYYKGNISSETKIGGVGGLFKKGISGALTNESM
                     MKPVYKGTGEVYLEPSFRHYLFMSLDNDSIIVDKGLFYCCSDTIEVKAFTQKNFSSAL
                     LGGEGFFQIELSGTGVIVLECVVPQSEIVEYELKNGEELKVDGNFAIARTSGVNFSVT
                     KSDKSLIGSALNGEGFLNTFTGNGTVWLAPTQVMYEKLSFGAMPTNDNMNNKVSKQK"
     gene            7317..7772
                     /gene="smpB"
                     /locus_tag="PC466_000344"
     CDS             7317..7772
                     /gene="smpB"
                     /locus_tag="PC466_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HDF2767780.1"
                     /translation="MAGKKILATNKRARHEYFIEETYECGIELKGTEVKSIRQGKVNL
                     SDGFASVDNSEVFLKQVHISPYEQGNIFNVDSLRVRKLLLHKHEIRKLIGATTIKGYS
                     LIPLSLYLKNGKVKVEIALAKGKKLYDKRQDMAKKDAQRRIEREMTGKY"
     gene            7930..8279
                     /gene="ssrA"
                     /locus_tag="PC466_000345"
     tmRNA           7930..8279
                     /gene="ssrA"
                     /locus_tag="PC466_000345"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(8953..9858)
                     /locus_tag="PC466_000346"
     CDS             complement(8953..9858)
                     /locus_tag="PC466_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P63C domain-containing protein"
                     /protein_id="HDF2767781.1"
                     /translation="MESKEKSILRATHFGIIKIGEKDLNCAVLENGSRIINKSTVFKA
                     FGRTKRGRKKDEIRVPSKPNLPSFIDAKNLSDYISDELEDMLINTIKYKTKNGRIVEG
                     YPAEIIPLICDVYLQARLDNKLAVQQEGLAIASEILVRSLSKIGIVALVDEATGYQYD
                     RDRDELQKILSMYISKEFLPWTKRFPDEFYRQMFRLKNWTYPRPSSKRPGIVGTYTNK
                     YVYDLLPPGVKEELQRVNPTVKPGQRKHKHHQFLTEDIGNDHLKNHLLKVITLMQASK
                     DWKDFNVLFNRAFNLPVQLEIEYDE"
     gene            10769..10984
                     /locus_tag="PC466_000347"
     CDS             10769..10984
                     /locus_tag="PC466_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3791 domain-containing protein"
                     /protein_id="HDF2767782.1"
                     /translation="MDERKLEFSIFCIEALAEKLNIDSEGVYKLLKHDTDILDNYIIP
                     CYEALHSQSKSYIVEDLIQVLEEKGVM"
     gene            10984..11463
                     /locus_tag="PC466_000348"
     CDS             10984..11463
                     /locus_tag="PC466_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3990 domain-containing protein"
                     /protein_id="HDF2767783.1"
                     /translation="MIVYHDSYCVAKTPNIIFLRDSLDFGKGFYVTSIKTQAINWIER
                     FKKRGKKAYLNSYSLDIDKLKENCKVKIFNSYNLEWLDFILECRNMSDVYMKYDVIIG
                     GIADDKIYNTIELYQDNLIEKDEALKRLKYYKPNEQICITNQNVIDKYLKFRCEEEV"
     gene            11469..11699
                     /locus_tag="PC466_000349"
     CDS             11469..11699
                     /locus_tag="PC466_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2767784.1"
                     /translation="MEANKTLLQILYKKIILEFSNQTGKSLEESMDYLYTSETYKLIS
                     EGVSDMHCKGHIYLAQELMLENGLMYHKGYPR"
     gene            complement(11815..12981)
                     /locus_tag="PC466_000350"
     CDS             complement(11815..12981)
                     /locus_tag="PC466_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDF2767785.1"
                     /translation="MATKRANGEGSIGKYKDGWRSRIMIGYNEDGKPIRKEFYGKTQK
                     EVKDKLDAYKKQYYLSSDISDDKITLEHWFYNWLFEYRIKDLKPKSFERYESIYRNYI
                     KDTDLGNVKLKDLRVSHMQKYYNRLLDSNKSIPTIRQINTKLKTCLSEAEKQGLIQRN
                     YCTMVNIPVEKKENRLEILTLEQQKNFIKAIEGHKLEVLFLVALGTGLRLGELLGLKW
                     FDIDFKNSNLTVKRTLQRTYFIDKNGNRELKVLEQEPKTSNSYRTVPIPKDVLNKLKE
                     HKVNQNVDILKAGELYRNDNYVFCNELGVPIDDKRPLRNLKSILSSLDIEPIKFHGLR
                     KTYATRLFENDVPPKTVQVLMGHYDISITLNIYTQVMEDKKVEAVEKLDKIFSL"
     gene            complement(12971..13723)
                     /locus_tag="PC466_000351"
     CDS             complement(12971..13723)
                     /locus_tag="PC466_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HDF2767786.1"
                     /translation="MNKSYIPKYTHKFPTNLPHGDKKYTLTYIRRMISEFVYDMGNLE
                     NNPFTFPEVQTLLDGITVGGHKLSDQNQILNIKSSWDYIIKLSNKENLSLNKDTICSI
                     HKIVAKDEALIVGDFRNGNIGIAGTTQYECIEATLLNNLFISDISIINKITNPLEKAI
                     IINLWLSYCQFFYDGNKRTARLTSNLILISNDIGVLSIPAKHKQEYNTLMLNFYETLE
                     ADEVIKFLLEKCITFFDGYNYKSYKELFKNGN"
     gene            complement(13815..14306)
                     /locus_tag="PC466_000352"
     CDS             complement(13815..14306)
                     /locus_tag="PC466_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2767787.1"
                     /translation="MINNTIGEKIKQYRKSINMSRNELANKIGCSVHAIAKYEQNQRI
                     PSLDMIRKISTALSIAINKLIVEENDLDTLTNNNINLKVFDKELDLVVHILENYGYDI
                     KTDYKKKFEITDNADTIKPISLSFSDFKDFSKNLNWVINGLVENFIQENSNGLIEDED
                     EEY"
     gene            complement(14557..15321)
                     /locus_tag="PC466_000353"
     CDS             complement(14557..15321)
                     /locus_tag="PC466_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2767788.1"
                     /translation="MQIGKNLKKIRKQKELTQIQLAEISGISRNALINYENDKRIPSI
                     DTLSKLAKALKIEKTIFYFDIENEVMTNEDVLYFLQSLFPEEYYSFDEFLNAISNLME
                     DDDIRITSSLLLGAWSDKDQYYKLGEKLELNENQVYNWILSDCVSNTELDFSLHPDDI
                     KEIIKNDVLIKQSIDELLDIGLSEENIEAIYDYFSEATDNGSNIRLKKLISQKENMTI
                     KNNDYFKLLQENNELKEKNKKLENTLKEIKKLLTKI"
     gene            15468..15668
                     /locus_tag="PC466_000354"
     CDS             15468..15668
                     /locus_tag="PC466_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2767789.1"
                     /translation="MGINLKIFRIKKGLKQQELADRVGISRYYLSNLETGKANNPSND
                     LMIKLSRALDTTVEELFFSKEE"
     gene            15672..15986
                     /locus_tag="PC466_000355"
     CDS             15672..15986
                     /locus_tag="PC466_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2767790.1"
                     /translation="MKENNNLEVLKTLQATLNIIVKNEEEAQEKKQGYKIIENAKRNK
                     AELITCKEASKLYPIGESKFRQLCHSKNKGFPCIWINNRVYIIKNKLDDWFIENANGI
                     KL"
     gene            16008..16751
                     /locus_tag="PC466_000356"
     CDS             16008..16751
                     /locus_tag="PC466_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2767791.1"
                     /translation="MSNKGWIKLYRELLDKSIWKDIKPERKVILITLLLMASHKENHV
                     FIDNKRIKIKSGQFISSYSKIAERCGKGVSYQMVRSCLLVFKNAGFLTYETTNKYIVI
                     TIENWELYQENIENQQPNQQTINNQSTTIKNIKNENNIIYSEIISKFNSTCIELSKVK
                     KLTDTRKRRINSIIREYDKEAVLEVINIVSKTSFLNGNNNTGWKANFDWIMNSSNFTK
                     ILEGNYHSKEIVINKETGIYNPDDSQLKW"
     gene            16764..18098
                     /locus_tag="PC466_000357"
     CDS             16764..18098
                     /locus_tag="PC466_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF2767792.1"
                     /translation="MNNSNNLIKNTEAEQSILGSILLDSTIVEELEQMLNEDMFYHEE
                     HKYIFNAIKEINKRNEVIDIITLTEELKRKGHLNNIGGISYITSLSTIVPTVSNFTSY
                     VSIVIEKYKNRNIIDKFNKFNLGEIDDNTLIYQLENDINKANQKLIKKDSSITAISER
                     AFEYINDEMNEGIKTGIKFLDDTIGGLYGGELTTIAAKSGRGKTALALQILRNVIFQG
                     KKVLFISGEMSDIQILFRNIASLTGISVVKMKNRNLNDDEIVKYIQALSIINQENNLY
                     INDSVNTVSGIKREIKSTKPSLVIIDYLQILDYEGKEVGEAKFADLSRQIKKITLDFN
                     IPVIQLAQLNDELKDERPKGDRVMRSSKQIYMDSNSVIYIHRPTEKEALNYCKTMGIE
                     DIRELRRREKGFGANLSEIIVAKNRDGESGFRPYWYIGNLFSFEECKKIQEI"
     gene            18348..18620
                     /locus_tag="PC466_000358"
     CDS             18348..18620
                     /locus_tag="PC466_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2767793.1"
                     /translation="MYDEIIEIYFDYWINEHMYRSILEKDEYYIECWKEVKKINELLE
                     INLEDDKKYLLVELNDLFNSLIEFERELSYKLGFKTGAKFIIELLK"
     gene            18893..20020
                     /locus_tag="PC466_000359"
     CDS             18893..20020
                     /locus_tag="PC466_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HDF2767794.1"
                     /translation="MIIPKLEPNDRKREFNKYSSEQINKVVYNYLFKNNMSNRKIDDE
                     ILDLSSKQSKGYQSMGIVHHLGINKNHKGIFTGYTIDKAIEVLKEDEIHFKQIINILL
                     EIRNINEYPIIVDSWELLDEKIALKTIDKSTLKHNGTGVPIEIRYFFEINNLGKNEKK
                     NVNFKYNDNYYSAVIEMDKLENPRSRIIWKSKFRDLLRSIFSEYYEKFLENKIEGKTN
                     LPKIRFIKLDSNNFNIEFIFTAEIEDDVLEEISQDNPLNINTINIELETEIRKEGKVK
                     YVYGKQYERNPRNRIEAIKYHGTKCIVCGFDFEKTYGDRGKGYIEIHHIKPLSSVGEE
                     SNINPKTDLVPICSNCHRMIHRKKDNVLSIDDLKQIIKDSK"
     gene            20500..21147
                     /gene="cas5"
                     /locus_tag="PC466_000360"
     CDS             20500..21147
                     /gene="cas5"
                     /locus_tag="PC466_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated protein Cas5"
                     /protein_id="HDF2767795.1"
                     /translation="MILNKIEIIGDMAHFKIPMHSKIQRTYEIPPISTVVGILKNIYG
                     EEIDDFILGYVIYHDGTFKDLQTIYKEINPNVKTLTDSDRFQTDVCPIEYLINPKLII
                     YTNIDKNIEFNEPLCLGKTNCLAKVLSLSEIEVNLIDKKAIGYNQYTDINIGDGMIKR
                     INTLTEYNEKKGYYDIYSSMVRENDEFEYGKYYDEDEQQNIFLWKWKKGGVIKCI"
     gene            21138..21902
                     /gene="cas6"
                     /locus_tag="PC466_000361"
     CDS             21138..21902
                     /gene="cas6"
                     /locus_tag="PC466_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endoribonuclease Cas6"
                     /protein_id="HDF2767796.1"
                     /translation="MHLVRRHLILTVDNEVVLDYNYQYELMKRIYEAIEINDKRKALS
                     LHNEGYKVDKKVFKLFNYTIMFENAKYLKEGIHLNPQTKIKLILSGYDDILNNIIKGF
                     IKCKVFKLNNIEFKVSDIEEDSKKNFNNITLYKVRSPIVASLYDLKSRKQVYLNPMQE
                     EFYKALHDNLGNKYKLIHNKEYTGELYFDIEDVLAVKKKYITNIKGKGFIIGYTDFEI
                     FVQANKDMQEVIYYCGLGEKNSIGMGLLTYITSRRA"
     gene            21904..23070
                     /locus_tag="PC466_000362"
     CDS             21904..23070
                     /locus_tag="PC466_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2767797.1"
                     /translation="MDRSYNVFVDNGLYVLAYYLNKDINDITYQDIENSIDLMSDKIE
                     EFVSCEKYSNLKSMCFSNSTLTQPKGKVTLNEKLKGFVKNQGDEYCSLCGQYKAKVKI
                     EDKEYNIGRSYMPNLVANTFYNFSNNLQGLNVCPYCLVLTMYSILNCRVSRYAFLYNS
                     TSSEFMEDYTFHIQKENLTDVELGAKKEKEKYSIVKLLESLVCKYNLFNGDIEQYMFN
                     NSGQSQDIQVNRIKNKYVNLLIKLQEKALLSNFEKLHLDRYILNGTLESNYLREVYRV
                     KKEEKMDEKEQKNFDELVIFLNREVNVLKKVKIDIIKKLTDKLKTSDLDIDKIYKELK
                     MLGKFYAYEDWLVNLNEMYYEKTGEKLFEAEDYIELDDIRSFRQIKNLILVSLI"
     gene            23091..24161
                     /locus_tag="PC466_000363"
     CDS             23091..24161
                     /locus_tag="PC466_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein"
                     /protein_id="HDF2767798.1"
                     /translation="MENKNSNRMLNIGYAIEVLCGRLNGSSSEVEKKNNSYKNSTYTK
                     KIGSRSRISSQCQKYNQKLFMEQVCGYEQNVKTKDGKQVKLVPNPFKYATDDIFGFMM
                     AEKLSIEEDVYKELSDEEKEIYKKNKKKYEVNITKKRKSRWQMNSLINVSNRKVEWEW
                     NVCGTTGDSMPYQVEVYSGVHTNIANLNIGKIGEYDISDIASEHRDYTTLEAKSIGVE
                     KLDKEEKFKRIEALLKSLEYLSVEGNKTNHLTDTKPKFVILGEYSWGNNVFQGIIKEN
                     GLDVEMLKESIEQNEEFRKSDIWIGINKFYDDTFNEIEVNNEKEQIKKYLEEEFEEYD
                     FMKISNVHQAFESYLKYLKETL"
     gene            24172..26157
                     /locus_tag="PC466_000364"
     CDS             24172..26157
                     /locus_tag="PC466_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated helicase/endonuclease Cas3"
                     /protein_id="HDF2767799.1"
                     /translation="MNNLYEYKAKSDGTSIDKHNEDMNYIMNQLVSIYNISNDMKNDL
                     YEAIVCHDVGKVVKSFQDNIESSTRRVRHELLSASIKYLNRGQKLAILTHHKDIKFLE
                     GQITNSIYEIELKELKELLDIEVEDIRPFIKEISRARNDDTRKLENILLKGYLQYCDH
                     IASAGIKSIDKGFNSIKDFSIPKGVSYNSIQEKVLNMDKNEDIMIMAMTGLGKTATSL
                     YWSNLVQNEYKSKRVYYILPYTASINSLYENLYNRNISVSMLHSKAPYFLNKISDEED
                     IKQLYQIYKKSVKQINVCTIFQLVKSVFSCKRFEMLLSQLKDSIFIVDEIHCFDTRVL
                     CYTLEFLKYLKENLNVKICIMSASIPTCLKKLIQERLQISTIIEPDSKDLIFRHRLNR
                     LSEGILDSIHKIENDLMQGKRVLICVNSVDLSQELYGRLQKYNPKLIHGRFNTRDREQ
                     AEKGIEESFLLIGTQSIEVSLDISYDVLYTELAPLDSLLQRFGRVNRRGDNAELSNIY
                     IYDYDRKLNIYDEDIINRTDIVISDIIHNDNSIVDESKVPSYLDNVYLDIDMDKYNKH
                     KVALEIIMKNMRLGVWNKSANNDMLNNDTISVVPECLLEEYKLYIDKKMYLEASSLFV
                     NVSVKRYNYNKKMFYECGDIVVTSYSYNDKLGLIFDC"
     repeat_region   26410..27032
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=26410..26438
                     /rpt_unit_seq="gtttaaattacactaagttagttataaat"
     gene            27477..29033
                     /locus_tag="PC466_000365"
                     /pseudo
     CDS             27477..29033
                     /locus_tag="PC466_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003444896.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182 family transposase"
     gene            30211..31425
                     /locus_tag="PC466_000366"
     CDS             30211..31425
                     /locus_tag="PC466_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FRG domain-containing protein"
                     /protein_id="HDF2767800.1"
                     /translation="MGEKMQSVICKIFDNKLLISNDLSEQDDVLYEVMDKFIDDIEYI
                     SKLGDEQIKSMLMEVNKFEEDSTEFELYMKNLCYLKQSYFIDTNDKSEINSIDIDILK
                     NVKIEDLVDITNIKLERNLNINIEHISKAVNKIYEENEKWKEYNIQNTMSKYIGIPES
                     EVIFISNLSQYVSFLSELDNAGDYVSRGQKDCMYELLPSLHRKYKKDYGIHSDEYEEA
                     FKQKIIYYDKEIKNRSSEELRAEGQHFGLPTEYLDFTEAHLISLLFAIEDYKYTKQHS
                     IVYFIDSISYNTDTIKRSEKLVNYSDTSAIDNCSKFSSRSFFIKVGNSNERIHFQKGC
                     FLKVSSEDKGEFKEKLKKYCKVVVINKDAKKEILKELFNLGITFENIYPDKDNVVKSI
                     KFYYDEIVGGNL"
     gene            31425..32717
                     /locus_tag="PC466_000367"
     CDS             31425..32717
                     /locus_tag="PC466_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF262 domain-containing protein"
                     /protein_id="HDF2767801.1"
                     /translation="MREQFKNSIKNIKSNRPLVSVQDIVNFIDKGEKYLKLSIDEIDE
                     MEILQGIVMSPDYQRTYKSSNKEESSIIESLLIGIPIPEIFLVKIGVNDMQIRHVMDG
                     QHRLNAIYRYVKNKYPLKNLDILGNDPLYDNKRFSELEKKDKIKILGSHLSILEFDGF
                     DNPEIEIELFKRYNRNTKPLEMQEIEMATYFSETSKYISKFINTLIKDKYKDEIDKSE
                     YKYANYKSDLLRIYNITKSRNDKQKNHQEICIIFSILENGLQENIRDGVTASKKFLEY
                     KSIQYKNNESEKLELLKDKFDEFNRMILKISEKIEYPFSTSLISDDKQRQSKYLIGVS
                     IVLASICYYYDIDLENNYLIQDIKKIISCSPIADIEYKASSTNMKNMILYLFIKNKIQ
                     DNKFESLNLKRDKIKEINTLVMNNDGYLNEQTRLLEIY"
     gene            complement(32944..33129)
                     /locus_tag="PC466_000368"
     CDS             complement(32944..33129)
                     /locus_tag="PC466_000368"
                     /inference="COORDINATES: protein motif:HMM:NF024729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HDF2767802.1"
                     /translation="MEGFWRILKVEMYYLRKLDTYEQLVKTIEDYIYYYNNFRYQKRL
                     NSMSPLEFRKYLNTEIA"
     gene            complement(33159..33548)
                     /locus_tag="PC466_000369"
     CDS             complement(33159..33548)
                     /locus_tag="PC466_000369"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="DDE-type integrase/transposase/recombinase"
                     /protein_id="HDF2767803.1"
                     /translation="MRAVGLSSVCRKKKFSYVKCTPEVIAENVLSRKFSADKTSQKWL
                     TGVTEFKLTNGMKAYLSAILDLDDRSIVSYVIGKSNNNNLVLETFDKAIELYPNAKPI
                     FHNDKSFQYTSKVFKSKLLTQGMIQSM"
     gene            complement(33560..34020)
                     /locus_tag="PC466_000370"
                     /pseudo
     CDS             complement(33560..34020)
                     /locus_tag="PC466_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888992.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            34449..35459
                     /locus_tag="PC466_000371"
     CDS             34449..35459
                     /locus_tag="PC466_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2767804.1"
                     /translation="MITKIKKTYIYLKEIQKIYKINEHKELVHIIKKLINDNKIKPIK
                     TSDLTPQHEQLYTKYRIIKQETEEDKKILEEINYKICDKLSIDYYRKNLVHYKNNRVA
                     IMDLNSYLIKKSDNLSKKISINERSYEIFKDEKFISSKVGKEVLKNLKIDLIKDLNVY
                     KTPEPFIYLSINRISPQKILIIENKDTYITITKMLLEGKEILKNKIDTVIYGEGKKII
                     NSIKGLKEDITIEYLTNKENEFLYWGDIDKTGLSIYTSLKDTNEINNIRLFEVAYEHM
                     IDKTKENTLRNIPKNQKDNFECGLENINNLNLKESIKNILVQGKYIPQEALNRFDLEE
                     YN"
     gene            35459..37078
                     /locus_tag="PC466_000372"
     CDS             35459..37078
                     /locus_tag="PC466_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2767805.1"
                     /translation="MEMINILEGYNKRVNCIGSYYLIATLANNRNKFKEFDNIQFYNL
                     LIQVLCYIFDRSLRRKNCLRDDIKDFIEEINRMDYKIMLSEDDLKDLANYIINGLTNS
                     GKVYLFTYYSLEQEKHIDESIKIIEDKNVKINNQERLSYSLTTEGYRLLLSTKEYDEL
                     FQIQISQMIAKLRIEKGDYQGAKEDIYDIINTLEIHQQKIDNYIKIIKVNILYIKEEK
                     YSTVIDTTVETLLEEMDKYEELKKEVKLLIKDKEDYLEKDEDIDKEKIKNIRTQLLQM
                     KELIDGIVLAKSTATNLLSRVQDFREEFKEILKKLLTTPVIKRFNFKEEILDRLEKDS
                     DFLLIIRELYISLFKVELPNRFNIGVAYQEQKLLNTREIENEIVNKDELEIIENKEKE
                     ERINYCENYYFDFFKYLIKYGLEKGQFTLEEFLKNYLKYDKVIYLEITKDSKLMRDII
                     IYFANQRESINIKKIIRMLENSAFSPNTDFQIERLIERLLVEDFELLNSVSHIKSNKI
                     FEDEMKINTEINLETMTAVKLEIANIKFEII"
     gene            37096..37824
                     /locus_tag="PC466_000373"
     CDS             37096..37824
                     /locus_tag="PC466_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2767806.1"
                     /translation="MNISLNDYKIANEIFYRLLKKSELKEKEAKELFLAYINNSNVRY
                     ALEAICEVSKIKIILISDTLYLIPNNDNDIFGFDYRRESLLGKDLKDSYLGYLIMTII
                     FSEFTNGVAPASYIQVLNLLDLVQESLERSIARDNLEEIEKSCEFNITILKNYWESKR
                     KWDESSKKGIETTSADFQIGFIRKIINFLKNEGLIVHIEDEDKIKPTRRFLDLMNNYF
                     LDEERKVLIEKLVLRKGESINASN"
     gene            37811..42166
                     /locus_tag="PC466_000374"
     CDS             37811..42166
                     /locus_tag="PC466_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2767807.1"
                     /translation="MPVINKYKIINFKFGMGQERILSNRTMELYGENLQVEAENTAGK
                     TMSIQTIIQSICPLSDVAKPFTAIYNKKEPLYSMTEWLLDDGKTLLLTGIGFEKKAGS
                     SKEEGKEKKDDLYKYFMFIIEESKEMEVDIDNIPLLKNNDKGIRIVQPLTASQDYIKM
                     LRDKYGKNKVHFFNNYLRKQHREKLEEYGINQSEWKEIIIKLNSNNKEGGLSDFVKEH
                     NTSEKLIRDKILPLIETSLTTEEFAPILQIKEQVRKCINNIIDMNEKLSDYKNYRDLN
                     IRVESLQNKINRILFIEEDKNNVLGELANLYVHIENKRNELNEEIKQYQKMKASKEEE
                     FKIVEYEEDSYEYFRKEKEIQDTQVEFDKAKNELNDKIEELELDEQYLNISKFKRKKK
                     GLEEGEKDKIEKESEKQRKEVNQEEITAIINRLGSSIHYCLKEESIINNEKLKENTNN
                     NIAIQEKKNQLNDDKSKLTKVLISKNSEIKYIEGKERDFNNQLHEFKLNNTDIKGFIS
                     NNFLGEVIDYTRYINYLNIKVKSIEENLESKVMQIEESNKLKDDINEAINNLKLDNHE
                     SYMKLQVLKTRKKDIDNFKEKYKIIKTRFEIDNELDNSTKLYKEVKQELNKMKLQVQD
                     LENNKKQLEKELEDLQNYKDIIFEEEILTDLERNGIKPIEGMKYLLTLDGDLEYKNNL
                     ISKNPLLPYSIIITNKEYQKLKQINLKNKTKISMPIFVRDNIEDTFITTSSNLVISNG
                     LNILSSFDNKALDPEKREKDMNLIKEQINSIRDKVEQYKAEIEILEEFKLLTNKIDFT
                     AEDLSIDVKIENYKKIIFEINNKIKSNENNEKNLSNKIKELYENKEKLLNNKNILFNK
                     LKDIRNIQDTYSIILENKNEITKLKTSIEKIEEEKKVIKKSIEDIDVNIFNLNSEKDR
                     INRHIDDTESKINKFKIYEPIKLENAKLEELEIKYKKYLEDPTKKEIETLNYEISVCL
                     KRIESITIELEEFRQLISSDNFENIPILFTIEELNKRIVLNKSKVDELRKLKYSIKSD
                     IDKNQGSLNTKREEILKKFNGKEPLSTSLIVNFNFEERKIDIKKDIKDIGEIIEGNRT
                     TCQNLEQELRDLKKYKVERKAITYQPEDIFIESKKLQSKLQNVEYNLIKSINSYKNTI
                     LEIKEFNYKHMEKYKNFIETLNVNKDNYSRQKEQVEIVLLVIREEISKLEKHSEQLRK
                     EKTIISRQIKDYVMDCIDEFKIINKLGKHKGQALFNISLPKSDKIENSLSLVDMLMDE
                     IVEEANLGDVEQKINTFYILNKTLNIGRIPVSVIKYEINRNETIKWNSINNETTGGQR
                     FCISFIVTILLMEYKRYDRNAIVDESKYKGKVLLMDNPFGETSQQDFLKEIFELAKKF
                     NVQIISYTHVTNASIRAMFNKIYLMTVEKTTSNKEFVDINEIKQNKTDELVYMSKFYI
                     GNKEELIQEDIFSLI"
     gene            42268..42477
                     /locus_tag="PC466_000375"
     CDS             42268..42477
                     /locus_tag="PC466_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2767808.1"
                     /translation="MKNFVIVSTKAALLRVIIVRLLLKIGLKTYKYLSYFMKKEKLKR
                     IIRPEGCELRVNRSIQVERAIAEQI"
     gene            42873..43013
                     /locus_tag="PC466_000376"
     CDS             42873..43013
                     /locus_tag="PC466_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2767809.1"
                     /translation="MKIKIKKYREKLLMIQNELAKSVGVRRETIVHLENGLMYHKGIQ
                     DK"
     gene            43151..44113
                     /locus_tag="PC466_000377"
     CDS             43151..44113
                     /locus_tag="PC466_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017561613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YafY family transcriptional regulator"
                     /protein_id="HDF2767810.1"
                     /translation="MAKIDNMMSILWMLNSDKKVTAKQISEKLEINIRTVYRHIDALS
                     ASGVPIISDTGHNGGYTLLNNFIKAPLFFDTEEQTALLHAAIFAKEEGSFLDDTLDKA
                     TSKLKMYSNQKQEETLTKHLIGFEVIKPTGKISIESVLKKLKNSIANELSVEINYRTA
                     HEEKSKCRIINPYGIVRWNNNWYIVAFCQMRNEIRSFRVDRISSVIETSNTFNRPKEF
                     SASEFFIRGIMDETKDEDNLISLVIEGKMNALDNLCQHWLLGYYLKERTSNKAIFKLQ
                     EEIIFTYVPNILIPYRKSIQIIEPLSLRDKMVEDLLELINHYQI"
     gene            44191..44820
                     /locus_tag="PC466_000378"
     CDS             44191..44820
                     /locus_tag="PC466_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HDF2767811.1"
                     /translation="MKKRKVYMYVFDTMSDWEVGYLTAELNTGRYFKKGLKPLKVITV
                     GVDKNPIITMGGLKVLPEITIDELNIESNDLLILPGGNTWTSIGHEKILEKSKEALEQ
                     RSIVAAICGATLGLAKTGLLDFRNHTSNDLEFLKMVILSYSGEKYYKMESAVNDENLI
                     TASGIAPLEFTVQVLKVLDVFKEEALSSWLNLYKTHDSKYFFELMNCNK"
     gene            45651..46067
                     /locus_tag="PC466_000379"
     CDS             45651..46067
                     /locus_tag="PC466_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2767812.1"
                     /translation="MSKSETGVKSKLILELLVITYLFIAVLATKYIFKGPSTASLPGL
                     SWLIVFGCYSIYNKKYNDLVDESSKFILSKVNQIAITIMMYSIVIIAIFFATPYISNI
                     NISNLDTGIILIAVLFIQSLSKLILYIYFDKRGICN"
     gene            46068..46280
                     /locus_tag="PC466_000380"
     CDS             46068..46280
                     /locus_tag="PC466_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2767813.1"
                     /translation="MAISMKTKIKEYREKLLMTQNELAKSVGVRRETIVHLENGKYNP
                     SLKLAMDIAKVFGTTVENLFEFIEED"
     gene            46915..47958
                     /locus_tag="PC466_000381"
     CDS             46915..47958
                     /locus_tag="PC466_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HDF2767814.1"
                     /translation="MKRKIAVVLLTVAMLLSLVACSNDNTSKSDKLEDTLVVYTTHGE
                     DMLGAISEEFTKETGVNVEFINLKGELADRVRSEKDNPQADIMFGGDTSTYMQLKEEG
                     LYEKTEPSWNNELDKSYKDSDGYWYGTIKTPVMMFYNTKLLSADKAPKDWSDLTKEEY
                     KDLIVTRDSLSSSMRSTISNLINYYSNTKSEEEAWKYLEDLNKNIKNYYNSGSVMYSA
                     IGKGEATISVAVLSDIIENKEKNNMPLEVVDAESGSVVITDCVAALKNAPHPNAAAKF
                     VDFVGSAKVQAMVANDFNRIPTLDSALKDSPKWMSKEYKAMDVDWSVIGKNQSNWIEK
                     WETDIIDNNKTIK"
     gene            48219..49093
                     /locus_tag="PC466_000382"
                     /pseudo
     CDS             48219..49093
                     /locus_tag="PC466_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421888.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            49112..50104
                     /locus_tag="PC466_000383"
     CDS             49112..50104
                     /locus_tag="PC466_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2767815.1"
                     /translation="MKNIELKEINHYYGKEKVLHDINISIKEGEFFTLLGPSGCGKTT
                     ILRIIGGFIKPSSGSIYVGDKNITNLEPENRNMGTVFQNYALFPNMTVEENVSYGLKI
                     KKLSKKIIKEKCDNYLELSGMKDFRKKKIDELSGGQQQRVAVARSLATEPTMLLLDEP
                     MSNLDIALRIKMREEIREIQQKTGITTLFITHDQQEALAISDRIAVMDKGKVLQIGVP
                     IEVYKSPLNDFVANFVGTSNCIGKEDYVNFNIEKETKPYIYKRPEEMILLQNTNQSGF
                     VKVKVESKNFLGAILEYTVSNDGKKYQVTELNRLNNSNKLNVGDMAYLGVLQGD"
     gene            50106..51800
                     /locus_tag="PC466_000384"
     CDS             50106..51800
                     /locus_tag="PC466_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HDF2767816.1"
                     /translation="MIKKINRSKFTSKNVIFIVLYSILFWILIGYIIIPIGNTFVQAF
                     QGKGGYSFEVFKEYFSNTNNLRVVSNTIILGLGSVFVCGIMGISLALYMTFVCDKHKK
                     IIHILLLSPMMIPGVIMVIACIQIYGESGIVTKSIEILLPFIKKPYDFSGLKGILFVV
                     AYTQYVYFYLNVYVALKYVDYSTVEAAKGMGASKLRVFFDVIWPVITPAVITSTIITF
                     ASGISSFSAPNLIGGGFKVLSTQIVRSKANNHMDIASVQVITLLLMGILFMILLQYYG
                     KKYGVVPSLKSQSYKVHNRKKDLFTFVCKVIIEIQIIMIMLPIVTIVYLSFVSTHSIM
                     TTIFPRDFTLENYQMIFQKSRVLQPILNSFKMSLMAVAVGLIITVPVSYLVIKKDTAY
                     NRLAKFIIMLPWSMPASAIAVNLINTFNQKSIFAFNESLIGGFYIVPIAYTIYALPLL
                     FSSNEVAMKSINLGLEESSRSLGAGRIKTFYNVIVPNMMPGIISGAILVFIRTIGEYT
                     MSALLYGVYNRPISISIVTNMQEFKIGVSMAYGVLVIGICYIALGIIFKLDRKRFT"
     gene            52351..53229
                     /locus_tag="PC466_000385"
     CDS             52351..53229
                     /locus_tag="PC466_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HDF2767817.1"
                     /translation="MLINMKEMLKVAQENQFAVPAFNIGSGQILKAVVQGANEKNAPV
                     ILAIHPNELSFLGDSFVVSCIEEANKSKVPMVIHLDHGENKEQILRAIRCGFTSVMID
                     GSHLPYEENVAISREIVEIAKGLNVSVEGELGTIGTTGTSSEGGTDEIIYTDSKLAKD
                     FVEKTGVDTLAIAIGTAHGIYPKGFKPELKLDLLKEIREVVDIPLVLHGGSSNPDEEI
                     AQAVKLGVCKINISSDVKSAYYKKCRELLEQNPSLYEPDTIYPPCIKAAREVIEFKMN
                     LFNAIDKLKCFYKNKN"
     gene            53265..55160
                     /locus_tag="PC466_000386"
     CDS             53265..55160
                     /locus_tag="PC466_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2767818.1"
                     /translation="MIGKILRSDCIVLDKQLQTKKDVINYMANHLYHGNYINNKEKFI
                     ADINKREKESSTNMGNLIAIPHAKSNVVNQPVMMYLRTDREITDNDGQKLRSFFMIAV
                     PESGSDEHLKIISKLATYLMEENFLKHLLSAETPYEILSIFNNKAAESGDFSNNQNKG
                     LIVGITGCPTGIAHTFMAKKALEEAGQELGYEVKIETHGAIGVENKLTKEDIKRAEYV
                     IIACDKEVQLSRFIGKKVLQKKVVDAKNVSLAKNLIINAENGMAKEIKPGGKTLEDSK
                     EMLQGSETKGVYKHLMSGVSEMIPFVVIGGIGIAIAFMFGIFASDPTHETYNPIAGFF
                     GQLGGDSAFKLFIPILAGFIAKSIAGRQGFPPAMIAGFMAVIGGSGFIGGMVAGFATG
                     YIALGVMKITENLPDVLKGVNAVLICPLLIAFTSGAIMFFVVNTPASWLNEALQSWLQ
                     SMSGTNKVLLGAILAGMMASDMGGPINKTASAFGLAMFSSNIFEPSAALMVGGMVPPL
                     AISLAMLIFKNKFTKEERKSSLPTAIMGASFITEGAIPFAAADPLRMIPANIIGSCIG
                     GAICMSLDITLMAPHGGIFVIPFACSAPVAYIACILIGTVITALIIGVAKPTIRSENS
                     EVELLGA"
     gene            55428..57335
                     /locus_tag="PC466_000387"
     CDS             55428..57335
                     /locus_tag="PC466_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDF2767819.1"
                     /translation="MLVSRQIEFLKLILNENKYRPIKYFKDKLNVSDKTLQKDLKMIE
                     KYLETFNIKIDIKRGYGILIEDLAKKNIDLINSLNIQSKENKSLSVEQRRMEILKYLL
                     LNSNNITSINQLADKYYVSKTSIVNDFKYIEAWIKEYNLKLNKTLEGTKIIGKEVDIR
                     KSIAKMMDDLLDENYEQHDISELTRLDSATFSALINLFDIDSIIFVETIITELEYNLG
                     YTINQPYYINLITHILICLKRIEEGNQIESQEEREISVDNLDELVYKNVTTLIDKIEN
                     RYRVKITKDEIMYIYIFLVSSGFSSENNSSYNDESDILSESEKVSSIMIENMSQFLNI
                     NLKNDDLLQKSLASHVRPMLNRLRYDIQIKNPLLGEIQERFSDVLGLCMMTINIMTEY
                     DNLKNISIDEVSYLATYFQAAIERNMSSKRVIVVCHTGYGTSQLLAARLKREFPEWTI
                     VDIVPMHQLSKRNLDDVDFVISTVNLDLKDKLHIVVSVLLMESDINNIKNALLSKPKK
                     SMNLDTNLLGMYLEDNIYFNFDVAQMESLIGVNLGSKYESISLGKDLNIYIHKQSKLN
                     KGIMNINNVTRTIDIYLEISNQSFLKNILMEISNLYRQKNYINYIIDCKSKEDIKILF
                     KNNLLEKTNGN"
     gene            57325..57774
                     /locus_tag="PC466_000388"
     CDS             57325..57774
                     /locus_tag="PC466_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2767820.1"
                     /translation="MEIREILTEESIILDLKSTTKEGIIQELVDKLYDTGSITLKSKF
                     IKALKHREKIGSTSIGYQMAMPHGKTKYVKKASIVIGKSKKGVDWPSIDGLPVKVIIM
                     FAMPQSGGNEDMILISKIAYILGGKNISERLLNVHTKKEILDIFYEV"
     gene            57874..58761
                     /locus_tag="PC466_000389"
     CDS             57874..58761
                     /locus_tag="PC466_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDF2767821.1"
                     /translation="MAIYLEMPKLIHEFPFRSLSNEGEVLTTPHWHKEIEILLITEGV
                     VNLFINDKPMQLKKGEIVIIKGGDIHYILPSPGSERLVFQFDISFFNDLILLNEEKES
                     LINLFSSIKKCSRDWSAKIRKSVFDILIDIYNEDLYKIEGYSYAIKGKMYNLIPILYR
                     QIPREIEENTVEYEINSKEILERLNNIFKYVEKNYKQPIKLEDVSYEVGFSVYYFTKF
                     FKKNTGKTFITFLNEYRLEKAKWILLNNNISIVDLVEEVGFGSTKTFYRVFKEKIGVS
                     PLEFKKRYNSLEKKGGASK"
     gene            59166..60614
                     /locus_tag="PC466_000390"
     CDS             59166..60614
                     /locus_tag="PC466_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HDF2767822.1"
                     /translation="MKLGKDFLWGGAISANQSEGFYLDGGKGLSQFDKLPLNDKRLKD
                     VCLDEDNILNENNQYYPSHIGIKFCENYKEDIAMLAEIGFKCFRFSISWSRIFPTGEE
                     SEPNEKGLQLYDNIIKELKKYNIEPLITISHFDIPYSLVEKYSGWADRRVVNLYVKYA
                     EILMKRYKDDVKYWIPFNEMNMIIHIPYIGAGLTFIADENQLQKKYQAAHHQLLANAK
                     TIEIGRYINKEFKFGCMLAAGKTYPYTCKPEDVFATLEHERHNLFFSDVQVRGVYPSF
                     MNYYLKSNQIKLIIKEEDLSTLKDNTVDFVSFSYYSSACSSARAEGLEKSKANGPETI
                     KNPYLPKSNSVWQNDPVGLRITMNQLYERYQLPLFIVENGLGTQDIVNEDGKIIDDYR
                     IDYMKEHIKNMILGVNEDGIELIGYLMWGCIDVTSVSEGKMTKRYGIIHVDSDDYGRG
                     SFKRTKKQSAFWYKKVIETDGEILFNDMETHA"
     gene            60640..63030
                     /locus_tag="PC466_000391"
     CDS             60640..63030
                     /locus_tag="PC466_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HDF2767823.1"
                     /translation="MSLIFTTKDQLIEQGFSKDTIKSNETLFTLANGHLGVRGNIEES
                     DFNNEYVDNMGTYVNGFYEESPITYGESAYGYAKQNQTICKLPNAHIVNFSIEGDCFD
                     LSKGITSEHTRILDLNEGIVKRSFIWENSRGRKVKVSIERLVSQDIEELMMISYTITP
                     LNFNGKIKFKNKMENSMEKFNCEKVDDPRVASINKKQFKINVKKYNNKYFMNLVTERS
                     RLGLWCGFDSYITCGNITNETYNVSDECIEREIEVYAKKDERLNLEIVVGYSRVYSDL
                     NLNEERLKSLECLESLKCLESEAHLKSLELVLREACNIGFDKVKNIQRKKMNEFWTTS
                     DVEIEGDKTLQLGIKTNLFHIYQSAGRDGKTNISAKGLTGDGYEGHYFWDTEMYILPF
                     FIYTQPSIARALLDYRYSILDASRERARELGINKGCLYSWRTINGNECSAYYPAGTAQ
                     FHINADIAYGIRTYFEATNDEEFMMQNGLEILIETARFWVEFGDYIELKNNKFCINGV
                     TGPDEYTAIVNNNYYTNLMAKYNLIYAVQMVDKFKHNLFSNEVFRKVKLQEYEVKDWI
                     NAAQNIYLPYDEEKKISKQDDSFLEKSVWDFKNTPKEKYPLLLNYHPLTIYRYQVNKQ
                     ADTVLSALLFPDEFSLEQKKRDFEYYEKITTHDSSLSRSIFGMMASEIGNHEKAYNYF
                     MDTALMDINNLQKNTSDGIHAANMGGTWMSLVYGFAGMKIKKDKLSFEPRIPKHWKNI
                     KFNILFRDNLVSVNIEEYKSYYKLIKGKNISILHDNKEIKLSKNIIEVNNCFKGSN"
     gene            63032..63703
                     /gene="pgmB"
                     /locus_tag="PC466_000392"
     CDS             63032..63703
                     /gene="pgmB"
                     /locus_tag="PC466_000392"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HDF2767824.1"
                     /translation="MKAVLFDLDGVITDTAKYHFEAWHEIAKSLDIEIDETFNEKLKG
                     ISREESLDKILLSANKVDSYTKEEKLKVCEEKNNIYIKLINSLTYKDILPGINELIKE
                     LKKNNVKLGIASASKNAPRILESLGIKDEFDCIVNPSLLERGKPYPDIFIEGSKMLNL
                     KQYDCVGIEDSYSGIKAINAANMTSIGVGKKEVLGKCDHIVEDTSLLNYNTLLQAWSK
                     KINLD"
     gene            63742..65142
                     /locus_tag="PC466_000393"
     CDS             63742..65142
                     /locus_tag="PC466_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDF2767825.1"
                     /translation="MKNKYEEVAQLIIDGLGGKDNIIDLTHCMTRLRFILKDEKKVNA
                     DKLKSIDKVVGVNSTSTQYQVIIGNEVGVVFNAIINKGINTTGDIKSDIKNENKKNSI
                     LNNIIDTITGCMTPMIPALTASGMIKVILSLCTTFNWLSSNSSTYRVLDIIGDVAFYF
                     MPIILAINAAKKFNVNTSIAVIVVGVFLHPNFSAWVSSGDPISFIGVPIQGVIYAASV
                     IPALLTVWMMSYIEKFINKLTPSMLKTILNPTLVLLISAPIALIVIGPIGNFLGEGLA
                     SIINLLQGRLGFIMVCLLAAAMPFIVMTGMHHALTPIFISAFATTGQESLILISQVCA
                     NLAQGGATLAVALRSKDSKMKQLASAAWISAIMGITEPALYGVTLKLKKPAMLASIGA
                     GIAGLFAGITHVTLYVPQNSIMAVLGLSGEKGISNIVNGLIVIFIALVAPFIMTYVFG
                     VEKNVKESTDNVVEEV"
     gene            65459..66301
                     /locus_tag="PC466_000394"
     CDS             65459..66301
                     /locus_tag="PC466_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDF2767826.1"
                     /translation="MIINKILNNNVVITLDDNDEEVIVMGKGIGYQKSKGNLIDKTKV
                     NKVFRISNKEISNKLQELLNNIPIEHMKLSSEIIEYAQIKLNKKLNESIYISLSDHTY
                     SAIQRMKEGINVKNAILWEIKRFYKEEFEIGMKALDIIENKTGIKLPEDEAGFIAFHI
                     VNAQLSEGHTLASDITKLIQEVLSIVRYHFRIEFHEESVFYYRFIMHLKFFAQRLLLD
                     SAHEGETDKELLSIIKSKYNKEFECVVKIKNFIKKQYNYILTDDELIYLTIHLAKVVK
                     DSNM"
     gene            66446..68374
                     /locus_tag="PC466_000395"
     CDS             66446..68374
                     /locus_tag="PC466_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF2767827.1"
                     /translation="MGKYKQLAQEIVNNVGGKENISGLVHCITRLRFTLKDESIANDN
                     VLKNMEGIVTVMKSGGQYQVVIGNHVEAVYKDVVEIIGLDDSSTSSETKKSGNILDKG
                     IDIISGIFQPVLGIMAACGMLKGFNALFVAMGLYSDVSGGYMVINAAGDALFTFLPLF
                     LGYTSAKKFGLKPMLGLALGAAVCYPAIQGSSISAGADVMYTLFKGTMFASPVYIDFF
                     GLPIVSIDYTGTVVPIIFIVYFASRCEKLFNKFVPDLVKFFFVPMLTLLITVPVALIV
                     IGPIATFGSTLISQIVISIRDFSPLLAGAIVGFTWQILVIFGMHWGFIPVYINNVMTL
                     GYDNVMMPFFACTFASSAVVLAIFFKTKDKKLKEMTIPNFISGIFGVTEPAIYGILLP
                     LKKPFIISCIASGIGGAFYGFFNLRKFITGGMGIFELPAMIEPDGGMGNLIVALSGIA
                     ISMVVAFVLTMILYKDEKVEESKKVRNKGKEEIKEVKSTKLEREIVASPIKGEVLKLS
                     DIEDAAFASGVLGQGVAIIPSDGKVVAPVDGVVTTLFPSLHAIGILSDTGVEVLIHIG
                     LNTIQLEGRGFEACIKQGDRITKGQTILNFDVDAIKELGYSTVTPIVITNSSQFLDVV
                     ETESKNIELEDNLITVLF"
     gene            68435..69862
                     /gene="ascB"
                     /locus_tag="PC466_000396"
     CDS             68435..69862
                     /gene="ascB"
                     /locus_tag="PC466_000396"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HDF2767828.1"
                     /translation="MSFKDDFLWGGATAANQCEGGYNEDERGLANVDVCPTGKDRTAV
                     ITGKLKMFDFDDEHYYPAKTGIDMYHNYKEDIKLFAEMGFKVYRMSIAWSRIFPKGDE
                     ETPNEKGLQFYENIFKECKKYKIEPLVTITHFDCPMHLVKKYGAWRNRKMIGFYEKLC
                     NVIFRRYRGLVKYWLTFNEINMILHAPFMGAGICFEEGEDVEKIKYQAAHHELVASAI
                     ATKIAHEVDSNNLVGCMFAAGSVYPYSCNPNDVWEATKLDRENYFFVDVQSKGKYPNY
                     ALKYMEQKGITPEMEPGDIELLNKYTVDFISFSYYNSRCVRTDENADDMAEGNIFTSA
                     KNPYLSYSQWGWPIDPLGLRITLNHVYDRYEKPLFIVENGLGAKDIADENGYVEDDYR
                     INYLREHIKAMHDAVSIDGVDLLGYTTWAPIDLVSAGTGEMEKRYGFIYVDRDNSGNG
                     SLRRMKKKSFEWYKKVIASNGEDLY"
     gene            70273..71049
                     /locus_tag="PC466_000397"
     CDS             70273..71049
                     /locus_tag="PC466_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDF2767829.1"
                     /translation="MKYQHIIEVDKELCIGCGLCKNDCPVNNIIIENKKSVIKKQDCL
                     MCGHCAAICPTKAITLTGFDEPPIELTNKPKLDSDELLMAIKSRRSIRKFKDKEVSSE
                     IVKQIIEAGRYTPSAKNSQDVSYIVLDNKKSIYENEAVKFFRKIKPIANIAIKYSKEV
                     EIDDNFFFKHAPIAIMIITKDKISGSLAASNMALMAESYGLGVLFSGYFSDVANNSPK
                     LKKLLGLKRSNHVLTTLVIGYPDVKYRRTAQKEVATVRYL"
     gene            71065..71430
                     /locus_tag="PC466_000398"
     CDS             71065..71430
                     /locus_tag="PC466_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HDF2767830.1"
                     /translation="MEKECQQRMQEITSKFKECRKAISAMGDETRQLILIALLESDFN
                     GIRVGEITKKTHLSRPAVSHHLKILKEAEIVNLRREGTKNYYYLDSKKSQWKSLTELI
                     NLIFVGIQHISENDIRKGD"
     gene            complement(71596..72345)
                     /locus_tag="PC466_000399"
     CDS             complement(71596..72345)
                     /locus_tag="PC466_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440038.1"
                     /note="N-terminal region resembles flavodoxins. C-terminal
                     ferrodoxin region binds two 4Fe-4S clusters; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EFR1 family ferrodoxin"
                     /protein_id="HDF2767831.1"
                     /translation="MILYFSGTGNSRYVARKIAQELNDELISLNQLIKEEKTDELISA
                     GKPFIFVCPTYAWRLPIVVTDFIKETKFLGDNRVYFVMTCGGDTAKSINYIQKLCKYK
                     EWQLKGMAEIKMPENYIALFSTTDKETSKQMIKEADKQIYRIISDIRNENEFETITPS
                     GLGGTIKSGIINTVFYKTIISAKGFHYTDKCIGCGKCVELCPLNNINLKNKKPVWKNS
                     CTHCMACICGCPTEAIEYKNKTQNRERYYLE"
     gene            complement(72790..73347)
                     /locus_tag="PC466_000400"
     CDS             complement(72790..73347)
                     /locus_tag="PC466_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HDF2767832.1"
                     /translation="MRTLKYAILGLLNRNPMTGYDIVKEFNFQLAEFWNAKHSQIYPE
                     LKKLVNEKLIVYDIKISGDVLEKKLYTITEKGKDEFLKWLEKDEPMERTPKDIFRLRM
                     YFSNNLDIDTRLILLEHQLLQHQERITFLYSQMERYSEVPPLDSNDFGDYIVLDGAII
                     REQGAIKWLTNCINHHKNLDNTTLK"
     gene            73599..74897
                     /locus_tag="PC466_000401"
     CDS             73599..74897
                     /locus_tag="PC466_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HDF2767833.1"
                     /translation="MNLTQKRWIILIASCFINLCIGSIYAWSVFASPMAEHLNSLAGT
                     TFTAASLAIVFTVTNSVGPITMITGGMINDKFGPKKVVFVGGLIFGIGMILAGFSKGL
                     PMLILSYGIITGLGVGMVYGCTISNSIKFFPDKSGLVGGITTAAYGFSSVIMPPVANW
                     IINKYGVTSAFKSIGLVFLIIVCVSSFFIKKCPADFTPEGWVPPEKKGKVRVVINKNW
                     KEMLSTPIFYLMIIILTCGAFYGLMCVSLASSLATNMIGMTSSDSAIVVSILALFNTL
                     GRIVAGYISDKIGRINTLSGALVISIFGLLCLLFSREGDVATFYIGIIIIGICFGSFM
                     GIFPGFTVDKFGPKNNSVNYGIMFIGFAFAGYIGPAVMKNVYSVDGNYQRAFIIAIII
                     ALIGFILTFLYKYINKIQNLKIENLIKGDIKNGKKISKSM"
     gene            74869..76818
                     /locus_tag="PC466_000402"
     CDS             74869..76818
                     /locus_tag="PC466_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015394831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HDF2767834.1"
                     /translation="MERKYPNLCKPIKIGNVTFKNRMFSAPMGGTDITADCTIGSKST
                     AFYELRAKGGAGAVTISECMVHPETDGSHAYHLDLKIVDSLASFTYTADAIRRHGAIP
                     SVELSHSGQYSGTYLVDKDKKRGLSQWGVSPSVRPDGLEIKELTEEIIAEIVESYGNV
                     AALAKRAGFEMIMIHGGHGWLINQFLSPYFNKRTDKYGGSLENRVRFAKEVLDSVRKA
                     VGPGFPIEFRMSGSELFEGGYDLDYGTEIAKLLESRVDLLHVSAGTYQRGFAVTHPSM
                     FLEHGCNVYLAEEIKKHVNIPVATIGALNDPEMMEEIIASGKADVIYMARALLADHEL
                     PRKVMSNQDEKIVKCLRCFTCMAERATTSTRRCTVNPLIGRELDGTEVVSVLKPKKVL
                     IAGGGPGGLQAAITAVKRGHKVILCEKTNELGGILKGEQALPFKYKMYELGNTFGKIA
                     KDLGVEVRLNTTVTKEYVENENVDALIIAVGSEPLVPPIEGLDGENVVIVNDYYVEKE
                     KVTDEVIVLGGGLAGCEAAIHLAQEEKTVHLVEMRAELAPDANIRHRPILLEEIERQG
                     IYVYTEHKGLSVTTEGVVCMNKSGNKINIPGTSVICALGQKPRREVVDTLLDSAPYVA
                     QIGDCVRASTITNAVYQGHHAALDI"
     gene            77255..77392
                     /locus_tag="PC466_000403"
     CDS             77255..77392
                     /locus_tag="PC466_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005610222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2767835.1"
                     /translation="MINENLKSLRKIHQYTQEELAEKLNVSRQSIAKWESGVSQTKGY
                     Y"
     gene            77620..77994
                     /locus_tag="PC466_000404"
     CDS             77620..77994
                     /locus_tag="PC466_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2500 domain-containing protein"
                     /protein_id="HDF2767836.1"
                     /translation="MFNLIEMLFPIMFILIFIIIVFTFVKGIATWFKNNNSPRLTVSA
                     RIVAKRQNTTHNNQPNAGDISGAHGFHTISSTSYYVTFQVDSGDRIELSVSGSEYGVL
                     AEGDKGQLTFQGTRYLTFDREN"
     gene            78010..78657
                     /locus_tag="PC466_000405"
     CDS             78010..78657
                     /locus_tag="PC466_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2767837.1"
                     /translation="MNKFLSQIRRIDNEISITRKIINTIFILCFGIVLGTFAKFLDTT
                     ASNTLPFIFEYLDISNFFGRFAIWLLIALYIAIYSHSSIRASLNVLVFFIGMVSSYYL
                     YSYFVAGFFPKNYAMIWLGFTVISPLLAFICWYAKGKSKISFILSVIIIAILFNFTFI
                     YGWIYFDVYSILEVIVFGCALIALKRNTFRETTYMILSAVVIAVILNMLVPFHFG"
     gene            79037..80116
                     /locus_tag="PC466_000406"
     CDS             79037..80116
                     /locus_tag="PC466_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HDF2767838.1"
                     /translation="MNDMKFIETLKQKRNVCDYSQSRLAQELQINRQNLNEIENGKTK
                     ASKEMKHILLHYLDYCNCTQPFTLTIDYLRVRFPTTDALEIIKNVLAMKSEYFIHEDY
                     GMYAYEEQYIYGDISVNASKDSSMGVLLELRGMGCRDLEYVLQVRGIDWYCFLRCCID
                     YQGVFKRIDLAVNDMGGLLDIEILRERYYANKVWKRSRTHEAVDSGKLSGTHGDTAKT
                     FYIGSKNSSIYFCLYEKEKEQKSKGIKTDIKNRFEIRLKNGKAGQTVEQLVFSRNPEQ
                     TIASFILTQIDFPDYILWDIFLDNVTTSLPFIMTPVAVNMDKIKRWLERQVMPSLLMI
                     KEIEKKTGANYLEEIDRHTRLTEKQ"
     gene            80938..81151
                     /locus_tag="PC466_000407"
                     /pseudo
     CDS             80938..81151
                     /locus_tag="PC466_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008394616.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA wybutosine-synthesizing protein 3-like
                     protein"
     gene            81263..82876
                     /locus_tag="PC466_000408"
     CDS             81263..82876
                     /locus_tag="PC466_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003019515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDF2767839.1"
                     /translation="MKQQIYNTALYLRLSRDDELQGESSSITTQRSMLRLYAKEHHLN
                     VIDEYIDDGWSGTNFERPSFQRMIEDIEAGKINCVVTKDLSRLGRNYIMTGQYTELYF
                     PSHNVRYIAIDDGVDSEKGESEIAPFKNIINEWVARDTSRKVKSAFKTKFAEGAHYGA
                     YAPLGYKKHPDIKGKLLVDDETKWIVEKIFSLAYQGYGSAKITKVLREEKVPTASWLN
                     FTRYGTFAHIFEGKPESKRYEWTIAHVKAILKSEVYIGNSVHNMQSTVSFKSKKKVRK
                     PESEWFRVENTHEPIIDKEVFYRVQEQIKSRRRQTKEKATPIFAGLVKCADCGWSMRF
                     ATNTANKTPYSYYACSYYGQFGKGTCSMHYIRYDVLYQAVLKRLQYWAKAVQQDEEKV
                     LNKIQKAGNAERIREKKKKASAFKKAENRQNEIDRLFAKMYEDRACEKITERNFVMLS
                     SKYQKEQIELEQQITNLREELSKMEQDMIGAEKWIELIKEYSVPKELTAPLLNAMIEK
                     ILIHEAITNEDNERIQEIEIYYRFIGKVD"
     gene            82905..83228
                     /locus_tag="PC466_000409"
                     /pseudo
     CDS             82905..83228
                     /locus_tag="PC466_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861830.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB/MazE/SpoVT family DNA-binding
                     domain-containing protein"
     gene            83260..84447
                     /locus_tag="PC466_000410"
     CDS             83260..84447
                     /locus_tag="PC466_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HDF2767840.1"
                     /translation="MSKIVFFSILAYGHTNPTIEVVRELVDRGNEVLYYSFNEFKDKI
                     EGAGAKFICCDKYLPELLPGDEKKIGKDFPGLIEMIVDTTISLDEKVCRELKDFNPDC
                     IVSDSLSFWGKLFAQKLNIPYVCSTTTFAFNKHTAKLMKQNFIEIIRMIFGVRRINKK
                     IKLLQRKGYEVKNFISIVSNDNDTDTIVYTSKEFQPMVETFSSKYSFVGPSVSKLIIK
                     PKERKRKLIYISLGTINNKNVSFYKNCINAFKDSDVDVIMSVGRSTDIKSLGNIPNNF
                     EVKNSVEQIAILQKTDVFITHSGMNSVNESLYYGVPMVLFPQHSEQRMVAKRVVHLGA
                     GIMLKEDKSESIKKAVFQVINDNEYKENATKLSKSFYNAGGSKKAADVILQIICNSRQ
                     VDI"
     gene            84639..85043
                     /locus_tag="PC466_000411"
     CDS             84639..85043
                     /locus_tag="PC466_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3139 domain-containing protein"
                     /protein_id="HDF2767841.1"
                     /translation="MKKYKVIFIVLIIGIISVTGFVVYKNCIKPWKDAETYIDKYMVK
                     QDISKDNIKSITKEKAKKASYEGILYKVYYKDDPRYEYQYFYSDNYHALYVNKVMLQI
                     YDVENNNKLLRSNEELKSVKYPPIYLKYKPDK"
BASE COUNT        34043 a         9223 c        13937 g        27970 t
ORIGIN      
        1 attaaatcaa attcttacac atataattat tggtatgctt attaacactt cagaaactct
       61 tatagtttaa aatttaaatt tattgttatt tattatttaa tttgagaaca tgatttattt
      121 tttatttgaa gctaataagt agagcatgat tctacagtat aatttcttaa atttttttta
      181 aaagtaatag ttcttattta tagtcaatat tgcctataga acttctgatt catttaattt
      241 ttaggaaaaa ataataatac ttacgctata aacacagaat tttagttgat aatataggta
      301 tttaaattta agatgaaata atacttttct caatatattt tattgtaact aagtttaatt
      361 ataagttaca attaaaaaaa cgctacttag gaggaatgta attatgggga tgataggatg
      421 ttatactaaa ataagtgaag agaatgtttt taaattacag caagcagaag aaaatttaca
      481 agattttgtt tttgaagatg ccaacgaaaa tagtactatc aatattgata aagcatggca
      541 tgccattcac tttactttga caggttgtcc ttttggtgga gatgatgaga atatatttag
      601 caaattagta ctaagtggaa acatacttat ggaaattgat ggagaatttc ctgtcatgtt
      661 gattacagca aatgatgtaa aaaaactatc aaaagcaatg aacagtttgg aagaacaagc
      721 atttagaaaa agatttaata ttaatgagat gttagaaaat aatatttatc ctgttatgaa
      781 tgatgagagt gaagatgatt tttttgaata tgtatgggca aatctaattg agcttaaaaa
      841 gtttatacaa gaagcatctg atgatggact agctgtaata ttttttataa tgtgataatt
      901 actaaaaaat tgtgaatatt agtgtcataa catatcttag atatgaagcc ttttgattgt
      961 atagaagaaa atacatatta tattagcctt ttaaaatata taagttaaat ttaaatctgt
     1021 aggtaaattt gtcttatgtc tttataaata tttatattag catatataaa ttagttttaa
     1081 atttttgcaa tatatagttg cagatatttt tatttatctt aaaaggctaa ataccctatc
     1141 ttattatatc cagtaattct tttggatact tatcacattt ttcattatat ataaaaatag
     1201 actcacaaat aaaataaata tatattaaat tatagcttca taaacttaaa aaatttcaga
     1261 aacaaagata ctttaattta attaaaaaca gaaaaattaa aatctttaga aaaaatttag
     1321 aaatttataa ataatatctt aagttttaga atttattatg aaaatacagt aaaaatttat
     1381 aaaaataaaa ttctataaaa ttatttctgg gggtgtattt atatatggaa atgaaaatag
     1441 cagtatccaa tcttagtaaa agatttggga aaaaacaagc tcttgataat ataaatcttg
     1501 aaatcgacag tggtatgttt ggtcttttag gaagaaatgg agcaggaaaa accacattta
     1561 tgagaatttt agccacttta ttatcaaaaa cagaaggttc aatacatatg tgtggagttc
     1621 ctattgagaa tactaaggaa attagaaata tggttggtta tttgccacaa gatttttcaa
     1681 tgtatcctaa catgacagta tataaagcaa tggattattt agcagtttta tcggatatac
     1741 cactaagaaa aagaagaaaa attatagcaa agttattaag caaagtaaac cttactaatt
     1801 atcaaaatgt gaaagtaaaa tctttatctg gaggtatgaa tagaaggctt gggatagcac
     1861 aagcattaat tcataatccc agagttttaa tagtggatga gccgacagca ggtcttgacc
     1921 cagaagaacg tataagattt agaaatttac tatgcgaaat tgcaaatgat agaatcgtta
     1981 ttttatctac acatattgtt ggagatatag aagctacatg tgaaaacgta gctatattgg
     2041 atagtggaaa agtcatatac aatggctcaa cagaagcatt agcaaaacta gctgaaggga
     2101 aagtatatag tattgaagta gataaaaaag acattgaaaa tataaaaagt agatttatag
     2161 ttataggaat gttgactcat ggtggaaagg ctatacttag gattatatca gatgataaac
     2221 cttttgagac agcagtaaat tgtaatccaa ctattgaaga tggctatatg cttataatgg
     2281 gaggagataa tatatgaatc tatttataaa agaatgtaaa aatatattaa agagtatggt
     2341 atattatatt tttattgtag ttttagtttt tttctatatt tctcaacttg gaagttcagt
     2401 ttcaaatgat gtaagtaaaa atattcctaa tgatggaaat ccattagttg ctccacaaaa
     2461 agtagagaat attgacgaat attactctgt acacaatcaa tatccatatg gtcaaaaaga
     2521 atctatgaaa acagaaaagg tcattccaaa tgcaactata aacctaatta gagaatatca
     2581 aaaaaacaca tatacaacgt atccaacagg ggtagttaag tatataaaat tagaccaaaa
     2641 taaaacgaag accatagaaa aatatataga agaaataact ggtaaaagta ttagcgaaat
     2701 aaatttaatt tggaaaactg atgaaagtat aaaaatagat tattctaaag tatctcttga
     2761 aagatttgaa gaaataatgc aaagagtaga cgacatttta ggaggagggt ctgcatatgc
     2821 ttttgacaag ttacaaagat ttggagtagt tccagttacc tatgatgaag ctatgaagaa
     2881 ttacaactat acaatacaaa aagataaagt tagtaatggg tatgcaagaa ttttttgcga
     2941 ttatataggt atagttttaa gtatatttcc agtatttgtg gcagttttta tgtcacttaa
     3001 agataagcgt tcaagaatga gagagattat ttattcaaaa caagtatctt catgcaaaat
     3061 agttttatca agatattttg cacttgtctt tataatgata ttgcctgtat taattttagg
     3121 tatgaaagat ttacttcctt tgattttctt tgctaaagat aaaggtatat ctattgataa
     3181 cttagcattt ataaaatata cattatggtg gatactacca actcttatga tagttacagc
     3241 tgtaggaatg agtattacta tattaacaga tacaccagta gcaattattg tgcaattaat
     3301 ttggtggctt tacagtataa attctacagg actcaaaggt gattattcaa caatggggct
     3361 aatgataaga cataatagtg tattaaatgg ggatattatt atacaaaact tcaatcaaat
     3421 tatgattaat agaattgtga taagcttggg agcattggtg cttgttttgt tagctatatt
     3481 cttatatgag caaaaaagaa gggggaatct tgatgtttgg gcaaagtttt caaaactgtt
     3541 tagttctaat aaaagaaaac ttcaaattaa gcactttaac taatttaata tgttcaatta
     3601 tattgctatg tatgattcct ctaatacaag gagtagctaa tttagacaga atttcaacag
     3661 ctatatgttt agaaaattat gttgcaataa tagggatagt aatgttggta cctgtatttt
     3721 cgctagagca atcaaaagaa attgatgaga tagtatcttc aaaatcatta tctcaagtta
     3781 ttgtacaatt aattaggata ctgatgtcaa ttataggtat agtggtatta atcataggtt
     3841 ttgtaaatgt tttaatatat cttggatgta attttccagt agttgagtat attattggaa
     3901 gtttcgcatc agctatgttt ataggaagtt taggaatgtt tttctcaaat ttatttaata
     3961 atacaatcat aggttacatg atatctatag gatatttaat tttaaatatg atgactaaag
     4021 gcaagtatgt tggaaaattt tttataatgt ctatgagtca aggtagtttt gatgagaaat
     4081 attggctgat acttggaagt gttgtgttga taattgcatc tctcttaata aaaccaataa
     4141 aaaggaagat taggtaataa aatgagagct tagataaaat aaaggtaata caaataaaaa
     4201 gtacatttat gaaatataaa tttattttta tatacacaaa cctacttaca atctctttat
     4261 gtatgtagat agatttatat atctgtagta taaaatatat atgtataccg aattttatca
     4321 aaggctctca aatttatatt tcaaagacac ttattgctat gacatacaca catgtatttt
     4381 ttcattttaa ttgtcatatt agcaatatga ctagtgttat aaactattga tacctcataa
     4441 caaaaaattc tccatcccct aaatgcgttt tctgtacctg agtctcaact attttaaatc
     4501 cttgagactt ataacatttt acagctctca tgttccaggt tcttacattt aatacaattg
     4561 gtttagtact atatttattt ctacattctt gtaatcctag gctaattatt tctttgccaa
     4621 ttcccattcc acaataatct ggttttatac caataccaaa gaatacataa cttccttcat
     4681 ccaataagtt tataaaacct atcaattctt tattgtcatt tataaaactt ataaaatttt
     4741 ttcttttatc ttcttttgat agtgaaaaat tcttcttttt aatttcctcc catggaggta
     4801 ggttgtatat tgaatattta ccttcatatt tccaattagt aacttcaata gcatgttctt
     4861 cagtaaattt aactttattt aaattcatat gtcctcctat taaaatattt aaggtaatta
     4921 atggtatttt aaattttaca aaataagtaa aactatttat atctatccat aaaatcttta
     4981 aaaattttac taacaattct tgtaccctgt actttttatt ggattcacag aagactataa
     5041 actaattttg aattaccttc taattcaaaa acatcacgat atatgtaatt tcttagcttg
     5101 attaaattct gttaaatctg tttcttatag ttgtataatc aacatcaata tctttatgtg
     5161 tattagttaa tttattggtt ttaggaactt attattaata tattgtattt gctccaatac
     5221 tccaagtagt aggtaaatta taggcaaatt atcaaatgta tatctatcca tgcttaaact
     5281 ttagagatac aataactact aaattagtat tctagtagtt ataaaaaaga atctttaaaa
     5341 atattaattt aacttatatt ttttaataaa ttttctaaaa tttaataatt taattatagc
     5401 tctaaatgat attttctaca gatataattt taaaaagatg tgtataagaa caaattcact
     5461 taaattttta aaatcaaata aagttgaatc tcttgactac cttgattgtt ttatgaaatt
     5521 aatatagatg taaacttttt aatatagatg taaactttac tattaaaaaa atacaagatt
     5581 ttagataagt taatgctaat tataaataat aagataagaa atataatatg acataagggc
     5641 taggaataag ataaatataa tcaaagaata agatatgaga ataattacca agagaaatca
     5701 ttaccttaat atgtttataa atgttagact atgttcctaa attgaatttt atatatcaag
     5761 tataataacc ttacagaatg tggaaatttt tatttaaaga atacacataa acatttccac
     5821 actctgattt tataataata atctaataaa atttatagtg actttataaa atcaataatg
     5881 atttaataaa tatttataaa acaactattt ttgcttagaa actttattat tcatattatc
     5941 attagtaggc attgctccaa aacttagttt ttcatacatt acttgagttg gagctagcca
     6001 aactgtacca ttaccagtaa atgtatttaa gaaaccttca ccatttaaag cagaaccaat
     6061 taaagattta tctgattttg taacagaaaa attaacccca gatgttcttg ctattgcaaa
     6121 gttaccatct acctttaatt cttctccatt tttcaattca tactctacaa tttcactttg
     6181 aggtacaaca cattccagaa cgattacacc agtaccactt aattctattt ggaagaagcc
     6241 ttcaccacca agtaaagcag atgagaagtt cttttgtgta aatgctttta cttctattgt
     6301 atcagagcaa caatagaata atcctttatc aacaattata gaatcattat caagactcat
     6361 aaataaataa tgtctaaaag aaggttccaa ataaacttct ccagtacctt tgtatacagg
     6421 tttcatcatt gattcattag taagtgctcc tgatattcct tttttaaaaa gacctccaac
     6481 accaccaatc ttagtttcag aagatatatt tcctttataa tagtataatg caccagcttc
     6541 tgtttttatt gatgaattat ttaattttat cttaatttgt ctagctttca aaccagcttc
     6601 tctagcaaaa tataatccca ttgccattaa tgggctagaa gctccctcaa gtttttcaaa
     6661 ttctaatatt tcaaattcgc ttttgccatc tgatgcattt tctaaaattt ttactttttt
     6721 gcttaaatcc atacaaattt ctcccaacta tgataaaatt tatctctaaa atattataag
     6781 atataactct atattacatt ttttttgaaa aaatcgctac tttatcatca aatttttaca
     6841 tatttttaag aagtttttga aatgtttaga tttaagttaa gttatttaag gatgtatagt
     6901 tatttcaata gatattttga gtattattta tcatttgtgg gtattatatt ttatgggcat
     6961 gttaaaatta tttagaagat agaagataga agatagaaga tagaagatag aagatagaag
     7021 atagaagata gaaaatttat aatatgtaat atttttgttt tgaaatttag aaatcagtgt
     7081 tactggttaa agttagttta gtattaagta tattcgaagt agttttttag ctattttcat
     7141 atctttatat tacttaatta tatatagcct aactaactta atatatcagt gaaatattga
     7201 ctaaaatgcc taaatatgtt atcatacaag ttagtcaaat aatttggcaa cattaaatat
     7261 ttagtaaatt tctaacattt atggaataaa tttctaacaa agaaggtgag atttatatgg
     7321 ctggtaaaaa aatattagca acaaacaaaa gagcaagaca tgaatatttt atagaagaaa
     7381 cttatgaatg tggaattgaa ttaaaaggaa cagaagtaaa atcaataaga caaggcaaag
     7441 ttaacctaag tgatggattt gcatctgtag ataatagtga agtattttta aaacaagttc
     7501 atataagtcc atatgagcaa ggaaatatat tcaatgttga ttctttaaga gttagaaaac
     7561 tattacttca taagcatgaa ataagaaaac ttattggagc aactactata aaggggtatt
     7621 cacttatacc acttagtttg tatctaaaaa acggtaaagt taaagtagag attgccttag
     7681 caaaaggtaa aaaactatat gataaacgtc aagatatggc taagaaagat gcacaaagac
     7741 gtatagaaag agaaatgaca ggtaagtatt aaactagata aaactgtatt ttttagaata
     7801 aaattcttta ttatctagaa cataacattg atttttattc ttaaaagtat tatattatat
     7861 atacattaaa aatttaataa aaatggtgat aaagtttgcg aaaagtctac tggactataa
     7921 actactcaag ggggcgtaaa ggtttcgacg tgggtttgga acttgaggct gcatgtcgtg
     7981 ttactctggg tcacgtaaaa actggggaac tttaaaataa acgcagacga taatttcgcg
     8041 atagcagcct agttgctgct cgtccctctt agtcctcctg ccgactaaga ctggacgtca
     8101 ttatgcaggg aactacttta ggggtgtctc gacctgaagt agattaattg ggactggcta
     8161 agcatagagc ctgccacttg gcgctatgtg aggtgagata ttagtgaagt tggctaagca
     8221 tgtagatgca gcaaggaaaa gatttgcgga caggggttcg actcccctcg tctccaccaa
     8281 tttttaaaaa agaatgatga aatacttgga aatactagtc tttattgact agtgtttttt
     8341 gttttggaga tgaaatccac caaccgtgcc ccaaccacag aaaaagagat ttttttgggg
     8401 tatattgggg tgcatttgat taatccatgg aacatataaa gaatactttt agagatatag
     8461 tgaatttgat gataatacaa taaatatttt atactgatga attgttttta tattatgctt
     8521 tttatttcaa tctaggaaat atataacttg tttaaactta tgattaaaag gataaagaag
     8581 tttaaagcat ataagtgcta cttaatctat tagagtaatt actagttata atgatataca
     8641 gaatcctata agattatgta taagtataga acaaatttat tatctatgtg ggatgctaat
     8701 ttaaattttt taattgtatt taaaaaaata agatgtaaaa aaggaattga aaaatgttaa
     8761 gataataaac acatagaatt attaagttta atactaacaa gactattgta tatagacaat
     8821 atattatata taaaatttaa ataatatatc ataaaagtac ctatactaat aagtactttt
     8881 atgatataag ttaattctat ttttataata taaattaaaa gtatttaaag cgttgttaaa
     8941 ggctatagtc tattattcat catattcgat ttcgagctgt acaggtagat tgaaagctct
     9001 attaaaaagc acattgaaat ctttccagtc ttttgatgct tgcattaagg ttataacctt
     9061 taataaatga ttttttaaat gatcattacc tatatcttct gttaaaaatt gatgatgttt
     9121 atgttttctt tgcccaggtt ttactgtggg gttaactctt tgaagttctt ctttaactcc
     9181 aggaggtaat aaatcataaa catatttatt tgtgtatgtt ccaactattc caggtctctt
     9241 agaacttggt ctagggtatg tccagttttt taatctgaac atttgtctat aaaattcatc
     9301 aggaaatctt tttgtccaag gtaaaaactc tttagaaata tacatagaca atattttttg
     9361 cagctcatca cgatctctat catattgata tcctgtagct tcatcaacta atgctacaat
     9421 ccctattttg gataaacttc ttactaaaat ttcgcttgct atagctagtc cttcttgctg
     9481 aacagctaat ttattatcaa gccttgcttg taaatataca tcacatataa gaggtattat
     9541 ttcagctgga taaccttcca caattcttcc gtttttagtc ttatatttta ttgtatttat
     9601 aagcatatct tctaattcat ctgaaatata atcagataga ttctttgcat caataaaact
     9661 tggtagatta ggcttagaag gtacacgaat ttcatctttt tttctaccac gctttgttct
     9721 tccaaaagct ttgaatactg tacttttatt tatgattctt gaaccatttt ctagtacagc
     9781 acaatttaaa tctttttcac ctatttttat aataccaaaa tgtgttgctc tcaatatact
     9841 tttttctttt gattccaatt taacaccatc ctttatttta ttttaataag taagatatta
     9901 cttagtatct cttcattaga taaattagta tttataagac taataatatc aattttaaaa
     9961 tatgtatata gataattgag tttttttatc atcttgtacg cagtattttt attaacaacg
    10021 atattttttg ataattttct atagctaata ttttcatcaa atataaataa attaatagca
    10081 agtagccatt ttctgtagtc tagtttagtt ttatgcataa tggtattagt tgtaattgaa
    10141 aacttactat tgcaaatatt gcaatgaaat aaatcattat aagtactaat tttatcagaa
    10201 taacaatagg ggcatattaa tgagtttttt aatttaagat tatataaaaa aatcttataa
    10261 gagacatctg ttggaaagtt tttataaata tcaaagtctt ttgtcataat ttaattatat
    10321 catgttgtag aaattaattt actgtattta agtgggtcaa atttaatata tatgtttttg
    10381 atagtgtaaa aattaaaata taattttagg catgtttgta ttgaataatg agcactttca
    10441 aattttatta gtgtaagagg tttcaaatta taaagtaatg aatgtatatt actatatgat
    10501 ttataattag aataaaattt ttataataga aatttaatat atcaaaatat cagttgagga
    10561 tattgttcaa gtggtatatc ttccctgagt taaaaaataa atgatgaaat atttggaaat
    10621 gctagtcttt atttgtttat gatattatgt aacatagaat tttaatatct actttatgat
    10681 ataatatttt tataaacata agatggttta agttattaat taataaaaat atatatatta
    10741 tataagtgga taggagttga ggtttgtaat ggatgaaaga aaactagaat tttctatttt
    10801 ttgcattgaa gctttagcag aaaagttgaa tatagattca gaaggagttt ataaacttct
    10861 taaacatgat actgatattt tagataacta tataatacct tgctatgaag cactacattc
    10921 tcaaagtaaa agttatatag tggaagattt aatacaagtg cttgaagaaa agggcgtgat
    10981 gtaataattg tatatcatga ttcatactgt gtggcaaaaa cgcctaatat tatcttctta
    11041 agagattctt tagattttgg aaaaggattc tatgtaacca gtataaaaac acaggcaatt
    11101 aactggatag aacgttttaa gaaaaggggt aaaaaagcat atttaaatag ctattctcta
    11161 gatattgata aattaaaaga aaactgcaag gtaaaaatct tcaatagtta taatttagaa
    11221 tggcttgact ttatattaga atgtagaaat atgagtgatg tatatatgaa atatgatgtt
    11281 ataataggtg gaattgctga tgataagatt tacaatacaa tagaactgta tcaagataat
    11341 cttattgaaa aagatgaagc tttaaaaaga ttaaaatact ataagccaaa tgaacaaata
    11401 tgtataacta atcaaaatgt aatagataaa tatttaaagt ttagatgtga agaggaggta
    11461 tagtgcttat ggaagcaaat aaaacattat tacagatact atataaaaaa attatattag
    11521 aattttctaa tcagacaggc aagagtttgg aagaaagtat ggattattta tatacttctg
    11581 aaacatataa acttataagt gagggtgtat cagatatgca ctgtaagggt catatatact
    11641 tggctcaaga attaatgcta gaaaatggat taatgtatca taaaggctat ccaagataaa
    11701 tagttaaaac tagatacgaa ttaaggatac aagataatat aaaattaatt tgtatcctta
    11761 tttgggtttt gtaattaact atatgaaatc atagtatttt tatgtatttg atttttacaa
    11821 tgaaaatatt ttatccaact tttctacagc ttcaaccttc ttatcttcca taacttgagt
    11881 atatatattt aaagttattg atatatcata atgacccatt aaaacttgta cagttttagg
    11941 aggaacatca ttctcaaaaa gtctagttgc ataagttttt ctaagaccat gaaactttat
    12001 aggttctata tctaagctgc ttaatataga ttttaaattc cttaaaggtc ttttatcatc
    12061 tatagggaca cctaattcat tgcaaaatac ataattatca tttctatata attctccagc
    12121 ctttaatata tccacatttt gatttacttt atgctctttc aatttattta aaacatcttt
    12181 tggaataggt acagtcctgt aagaatttga tgtctttggt tcttgctcta atactttaag
    12241 ctctctattt ccatttttat ctataaaata tgttctttga agggttcttt taactgttaa
    12301 attagaattt ttaaaatcaa tatcaaacca tttaagtcct aataattctc ctaatctaag
    12361 tccagtacca agagcaacca aaaataatac ttctaattta tgcccctcta tagcttttat
    12421 aaaattcttt tgttgttcaa gagtcaatat ttcaagccta ttttcctttt tctcaactgg
    12481 tatatttacc atagtacaat aattacgttg tataagacct tgtttttcag cttctgataa
    12541 gcaggttttc agtttagtgt ttatttgcct tatagtaggt atacttttat tggaatcaag
    12601 caatctattg taatattttt gcatgtgaga tactcttaag tcctttaact taacattgcc
    12661 taaatcagta tctttaatat aattacgata gatgctttca tatctttcaa atgactttgg
    12721 ttttaaatct tttattctat attcaaacaa ccaattgtaa aaccaatgct ctaaagttat
    12781 tttatcatct gaaatatcag aacttaaata atattgtttt ttataagcat caagtttatc
    12841 tttaacttcc ttttgagttt taccataaaa ttcttttctt attggttttc catcttcatt
    12901 ataaccaatc attatacgag aacgccaacc atctttatat tttccgatag agccttctcc
    12961 attagctctt ttagttgcca tttttaaaca actccttata tgatttatag ttatatccat
    13021 cgaagaatgt aatacatttc tctaataaga attttataac ttcatcagct tctagtgttt
    13081 catagaagtt tagcattaat gtgttgtatt cttgtttatg tttggctggt attgatagaa
    13141 ctcctatatc attacttata agtattaggt ttgaggtaag tcgagcagtt cttttgttac
    13201 catcatagaa gaattgacaa taggacaacc ataaatttat tattatagcc ttttctaagg
    13261 ggttagttat tttatttatg atacttatgt cacttataaa taaattattt aatagagtgg
    13321 cttctatgca ctcatattga gtagtaccag ctatacctat gttaccgttt ctaaaatctc
    13381 caacaattag agcttcatct tttgcaacta ttttatgtat agagcaaatt gtatctttat
    13441 ttaaagataa gttttctttg ttacttaatt ttattatata atcccatgat gattttatat
    13501 ttagtatttg attttggtca cttaatttat gtccacctac tgttatacca tcaagtaatg
    13561 tttgtacttc tgggaatgtg aaggggttat tttctaggtt acccatatca tatacaaatt
    13621 cacttatcat tcttctaatg tatgttaaag tatacttttt atctccatga ggtagattcg
    13681 tagggaattt atgtgtgtat tttggtatat atgatttatt catgatttta gctcctttca
    13741 tatctaattt ttatttatta actatgaatg tataaaagtt aataggtaaa cccatatttt
    13801 gaaaatgtgc aatactaata ttcttcatcc tcatcttcaa taagaccatt agagttttct
    13861 tgtataaaat tttcaacaag accatttatc acccaattta gatttttgga gaagtctttg
    13921 aagtcagaga agcttaagct aattggtttt attgtatctg cattatctgt aatttcaaac
    13981 ttttttttat agtctgtttt tatatcataa ccataatttt ctaatatgtg aactactaaa
    14041 tccaactctt tatcaaatac ttttaaatta atattattat ttgttaaagt atctaaatca
    14101 ttttcttcaa caatgagttt atttatggca attgataaag cagtagatat ttttcttatc
    14161 atatctagac taggtattct ttgattttgc tcatatttag ctatagcatg aactgaacaa
    14221 ccaatcttgt tggctagctc attccttgac atatttatcg atttcctata ttgtttaatc
    14281 ttttctccga ttgtattatt tatcataatt ccaccttaaa tatatcatca aacaatgatt
    14341 gtatttttac acatataaag gagttatttt ctagattatc tatatcatat actaacttac
    14401 tcataattct tttaatgtat gttagagtat attttttatc tccataaaat aaattagtag
    14461 ggtatttata tgtgtatttt agcatatatg ctttattaat aattgtaact ccatttgtag
    14521 ttttttatca ttgctttaga tagtattgat attattttat attttagtta gtagtttttt
    14581 tatttcttta agtgtatttt caagcttttt atttttttcc tttaattcat tattttcttg
    14641 taataattta aagtaatcat tatttttaat agtcatattt tctttttgag atattaactt
    14701 ttttagtcga atgttactcc cattatctgt tgcctcacta aagtaatcat agattgcttc
    14761 tatattttct tctgatagac caatatctaa taattcatca attgattgtt ttataagaac
    14821 atcattttta ataatttctt ttatatcatc aggatgtaat gaaaaatcta attcagtatt
    14881 agatacacaa tctgaaagta tccaattata aacttgattt tcatttagtt ctaatttttc
    14941 accaagttta taatattggt ctttatcaga ccaagcacct agcaataaac ttgaggtaat
    15001 cctaatatca tcatcttcca taagatttga aatagcattt aaaaattcat caaaagaata
    15061 gtattcttct gggaataaag actgtaaaaa atataaaaca tcttcattag tcattacttc
    15121 attttcaata tcaaaataaa agatagtctt ttcaattttt aaagctttag cgagttttga
    15181 taaggtatct atactaggta ttcttttatc attttcataa tttattagag catttcttga
    15241 gatgccacta atttcagcaa gttgaatctg tgttagttct ttttgttttc ttatcttttt
    15301 taagtttttt ccaatttgca atattatcac ctcgtataaa gtatatccca aaagtacaca
    15361 aatgagaaca gaaaaataat atattcttat tgacagcaca catatgtcga cattataatt
    15421 aaaatgtaaa gtttacgaat gtaaactaga aaaaaggagg aaaaagtatg ggaatcaatt
    15481 taaaaatatt taggattaaa aaaggtttaa agcaacaaga actggcagat agagttggta
    15541 tatcaagata ttatttgtca aacttggaaa caggtaaggc taataatcca agcaatgatt
    15601 tgatgattaa actatctaga gctttagata caacagtaga agaattattt tttagtaagg
    15661 aggagtaaaa tatgaaagag aataataatt tagaagtttt aaagacatta caagctactt
    15721 taaacattat tgtaaagaat gaagaagaag cacaagaaaa aaagcaagga tataaaatta
    15781 ttgaaaatgc gaaaagaaat aaagctgaac ttataacatg taaagaagca tctaagcttt
    15841 atcctatagg agaatcaaaa tttaggcagt tatgtcactc taaaaataaa ggtttccctt
    15901 gtatatggat aaataatcga gtatacataa taaaaaacaa attggatgat tggtttattg
    15961 aaaatgcaaa tggtatcaag ttatagtctt aaagtaggtg tttgcaattg agcaataaag
    16021 ggtggataaa gctttacagg gagttgttgg ataaatcaat ttggaaagat attaaaccag
    16081 aaagaaaagt aatattaata actctattac ttatggctag tcataaagaa aatcatgttt
    16141 ttatagataa taaaaggata aaaataaagt ctggacaatt tatttcttct tatagcaaaa
    16201 tagctgaaag atgtggtaaa ggagttagtt atcaaatggt tagaagttgt ttgttggttt
    16261 ttaaaaatgc tggttttcta acatacgaaa caacaaacaa atatatagtc ataactattg
    16321 aaaactggga gctttaccaa gagaacatag aaaatcaaca acctaatcaa cagacgatta
    16381 acaatcaatc aacaacaatc aagaatataa agaatgaaaa taatattata tatagtgaaa
    16441 ttataagcaa atttaactca acttgtattg aactttcaaa ggtcaagaaa ctaacagaca
    16501 caagaaagag gagaataaat tcaataataa gagaatatga taaagaagct gtattagagg
    16561 ttataaatat agttagtaaa acaagttttc tgaatggaaa taataataca ggatggaaag
    16621 caaattttga ttggataatg aattcaagta attttaccaa gatactagag ggcaattatc
    16681 atagcaagga aattgtcata aataaagaga caggaatata taatccagat gattcacaat
    16741 taaagtggta aggaggttat attataaata attcaaacaa cttaattaaa aatacagaag
    16801 cagagcaatc aatattagga agcattttat tagactcaac aatagtagaa gagttagagc
    16861 aaatgttaaa tgaagacatg ttttatcatg aggaacataa atacatattt aatgctataa
    16921 aagaaataaa taagagaaat gaagtaatag atataataac tcttacagaa gaattaaaga
    16981 gaaaaggtca tttgaataat attggaggta taagctatat taccagtttg tcaacaatag
    17041 tcccaacagt atcaaatttc acgagttatg tcagtatagt tattgaaaaa tataaaaata
    17101 gaaatataat tgataaattc aataagttca atcttggaga aatagatgat aatactctta
    17161 tatatcagtt agaaaatgat ataaataaag ccaatcagaa attaataaaa aaggattcaa
    17221 gtataacagc catatcagag agagcctttg aatatataaa tgatgaaatg aatgaaggta
    17281 ttaagactgg aataaagttc ttagatgata ctataggagg tttatatgga ggtgaactaa
    17341 ctacaatagc agccaaaagt ggaaggggga aaacagcatt agctttacaa atacttagaa
    17401 atgtaatatt tcaaggaaag aaagtacttt ttataagtgg agaaatgagt gatatacaga
    17461 ttctgtttag aaatatagcc tcactaactg gaatatcagt tgtaaaaatg aaaaatagaa
    17521 atctaaatga tgatgaaata gtcaaatata tacaagcttt aagcataata aatcaagaaa
    17581 ataaccttta tataaatgac tctgtaaata cagtatcagg gataaagaga gaaataaaga
    17641 gtactaagcc tagcttagtc ataattgatt atttgcaaat tttggattat gaaggtaaag
    17701 aagtaggaga agctaaattt gctgacttat caaggcaaat aaaaaagatt actttagatt
    17761 ttaatatacc agttattcag cttgctcaat taaatgatga attgaaggat gaaagaccta
    17821 aaggggatag agtaatgaga agctcaaagc agatatatat ggattctaat tcagttatat
    17881 atattcatag acctacagaa aaagaggctc ttaattattg caagacaatg ggaattgagg
    17941 atataagaga gttgagacga agagaaaaag gttttggtgc taatttaagt gagattattg
    18001 ttgccaaaaa tagagatggt gagtcaggat ttagaccata ttggtatata ggaaatttgt
    18061 tttcttttga agaatgtaag aagatacaag agatataaaa aagaagcatg atttattaag
    18121 taatagataa attatgtttc aagaagtatt gaatggtaaa tatataaaac ttaattagat
    18181 gtaatagaga tttaaaatat attgagttta gatttaaatg cttattagaa aaaggtagtt
    18241 gccatataaa tataacaact acctttataa attaggtact taatgtacac taacctagca
    18301 acttaagtat atattaagta cctgatgaaa gtcaaggagg tactaaaatg tatgatgaaa
    18361 ttatagaaat atattttgat tattggataa atgaacatat gtatagaagt attttagaaa
    18421 aagatgagta ttatattgaa tgttggaaag aggttaaaaa aattaatgag ttattggaaa
    18481 taaatttgga agatgataag aaatatctgt tggttgaatt aaatgatttg tttaattcat
    18541 taatagaatt tgaaagagaa cttagttata aattaggatt taaaacagga gcaaaattta
    18601 taatagagtt gttgaagtaa ttaatttgtg tatctcaata gaataattaa atagtaaatc
    18661 gagattatta ataagttgta ctagaatatt ttaagtgaag tatatattaa ttatattgtt
    18721 taaaataaat atatttaata aagaggggat aagtatgccc tcttttattt ttatgcaatc
    18781 aatgacattg taggatttac gtattttgat aaatagcaca atatatttta ataataaata
    18841 tatgatacaa taattttatt aaaatctaaa ataatcaatt gaggaggaga atatgataat
    18901 acctaagtta gagcctaatg atagaaaaag agagtttaat aaatactcat cagagcaaat
    18961 aaacaaagta gtttataatt atttatttaa aaataatatg agtaatagaa agatagatga
    19021 tgagatacta gatttatcat caaaacaaag taaaggttat caatcaatgg gtatagtgca
    19081 tcatttagga ataaataaaa atcataaagg tatttttaca ggatacacaa tagataaagc
    19141 aattgaagtt cttaaggaag atgagataca tttcaagcag attattaata tacttttaga
    19201 aattagaaat ataaatgagt atcctataat agttgactct tgggagttat tagatgagaa
    19261 aatagcttta aaaacaattg ataaatctac attaaaacat aatgggacag gagttccaat
    19321 agaaataaga tatttttttg agataaataa tttaggaaag aatgaaaaga aaaatgtgaa
    19381 ttttaaatat aatgataatt attatagtgc agttatagag atggataaat tagagaatcc
    19441 aagaagtaga ataatttgga aatctaagtt tagagattta ctaagaagta tattttctga
    19501 gtattatgag aaattcttag aaaataaaat agaaggaaaa acaaatttac ctaaaataag
    19561 attcataaaa cttgatagta ataattttaa catagaattc atttttactg ctgaaataga
    19621 agacgatgta ttagaggaga taagtcaaga taatcctttg aacattaata ctattaatat
    19681 agaattagaa actgaaatta gaaaagaagg gaaagttaaa tatgtttatg ggaaacagta
    19741 tgagcgtaac cccagaaata gaatagaagc aataaaatat catggcacaa agtgtattgt
    19801 atgtgggttt gacttcgaaa aaacgtatgg agatagaggt aagggataca tagaaattca
    19861 tcatattaaa ccattaagtt ctgttggaga agaaagcaat ataaatccca aaacagattt
    19921 ggtgccaata tgttcaaatt gtcatagaat gattcacagg aagaaagata atgttttgag
    19981 tattgatgat ttgaagcaaa ttataaaaga tagtaaataa tgcttatgtg tggcagagat
    20041 gtataaagta tatattctaa actagttaac aacaaatact aatataaaaa atcaaaaaat
    20101 ttattaggaa aaggtagttg ctaaagtata acagctactt ttataaatta agtatttgag
    20161 gtatattagt ctaaccgatt aggtatatct taagttattg atgaaaatta attaagacta
    20221 acatgtatga tgaatccata gaaatgtatt tttattgtta aataaatgaa catacataga
    20281 aatattttag aaaattacaa gtactatatt gaaagtttga aggagaacct tgatttaagg
    20341 taagtgtaaa gtttttagaa acttcactaa aataatctaa ttaagttata tatttgttac
    20401 ttttaggaaa ataatggtaa aaattaaagg tttttataaa tgaatgtcta attttataaa
    20461 taaaatggag tattttaact aaatatttga ggagataaaa tgatattaaa taaaatcgaa
    20521 ataattggag atatggctca ctttaaaatt cctatgcata gcaagataca aagaacatat
    20581 gaaattccac caatatcaac agttgtcgga attttaaaaa atatatatgg tgaagaaata
    20641 gatgatttta tattaggata tgttatatat catgatggta catttaaaga tttacagact
    20701 atatataaag aaatcaatcc aaatgtaaaa acattgacag atagcgatag atttcaaact
    20761 gatgtatgtc ccattgaata cctaattaat cctaaactta tcatatatac taacatagat
    20821 aaaaatatag aatttaatga gccgctatgt ttaggtaaga ctaattgttt agcgaaggta
    20881 ttatctttaa gtgaaattga agtaaatcta atagataaaa aagctattgg atacaatcaa
    20941 tatacagata ttaatattgg agatggaatg ataaaaagaa taaatacatt gacagagtat
    21001 aatgaaaaaa aaggttatta tgatatatat tcttcaatgg taagagaaaa tgatgagttt
    21061 gaatatggta aatattatga tgaagatgag caacagaata tttttttatg gaaatggaaa
    21121 aaagggggag taattaaatg catttagtaa gaagacattt gatactcaca gtggataatg
    21181 aagttgtatt agattacaat taccagtatg agctaatgaa aaggatatat gaagctatag
    21241 aaattaatga taaaagaaaa gcactaagtc ttcacaatga aggctataag gtggataaga
    21301 aagtatttaa attatttaat tacacaatta tgtttgaaaa tgctaagtat ttaaaagagg
    21361 gaatacattt aaatccccaa acaaaaatca aattaatttt aagtggatat gatgatatat
    21421 tgaataatat tataaaaggt tttattaaat gtaaagtatt taaattgaat aatatagagt
    21481 ttaaagtttc agatatagaa gaagattcaa agaaaaattt taataatata acactttata
    21541 aagtaaggtc acctattgta gcaagtttat atgatttaaa aagtaggaaa caagtatact
    21601 taaatccaat gcaagaagag ttttataaag cattacatga taatttagga aataagtata
    21661 agcttataca taataaagaa tatactggtg aactatactt tgatattgag gatgtattag
    21721 cagtaaaaaa gaaatatata actaatataa aaggaaaagg atttataatt ggatatacag
    21781 attttgaaat atttgtacaa gctaataaag atatgcaaga agtaatttat tattgtggat
    21841 taggtgaaaa aaatagtata ggaatggggt tactaactta tataacttct aggagggctt
    21901 aatatggata gaagttacaa tgtatttgtt gataatggtc tatatgtgtt ggcttattat
    21961 ctgaacaaag atattaatga tataacttat caagatatag agaatagtat agatttaatg
    22021 agtgataaaa ttgaagaatt tgtaagttgc gaaaaatact ctaatttaaa aagtatgtgc
    22081 tttagcaatt ctacgctaac tcaaccaaaa ggaaaagtta ctttaaatga gaagttaaaa
    22141 ggttttgtta aaaatcaagg agatgaatat tgtagtttat gtggtcaata taaggccaaa
    22201 gtcaaaattg aagataaaga atacaatata gggagaagtt atatgcctaa tttggttgca
    22261 aatacatttt ataatttctc caataatttg caaggtttga atgtatgtcc atattgttta
    22321 gtattgacta tgtattcaat tctgaattgt agagtaagta ggtatgcttt tttatacaat
    22381 tctacatcaa gcgaatttat ggaagattat actttccata ttcaaaaaga aaatttaact
    22441 gatgtagagt taggagcaaa gaaagaaaaa gaaaagtatt caattgtaaa attattagaa
    22501 agtctagtgt gtaaatataa cttatttaat ggtgatatag agcaatatat gtttaataac
    22561 tctggtcaat ctcaggatat tcaggtaaat agaataaaaa ataaatatgt gaatttatta
    22621 ataaaattac aggaaaaagc actactatca aactttgaaa agttacattt ggataggtat
    22681 atcttgaatg gtactttaga aagcaattat ctcagagaag tatatagggt aaaaaaggaa
    22741 gaaaaaatgg atgagaaaga acaaaagaat tttgatgaac ttgttatttt tttaaacagg
    22801 gaggtaaatg tattgaaaaa agtcaaaata gatataataa aaaaattaac ggataaatta
    22861 aaaactagtg acttagatat agacaaaata tataaggagc ttaaaatgtt aggaaaattt
    22921 tatgcatatg aggactggtt agttaactta aatgaaatgt attatgaaaa aactggagaa
    22981 aaactatttg aagcagagga ttatattgag ttggatgata taagaagctt tagacagatt
    23041 aaaaatttaa tattagtaag tttaatttaa taatattatg gagggttaaa atggaaaata
    23101 aaaattcaaa tagaatgtta aatataggct atgcaataga agttttatgt gggcgattaa
    23161 atggaagtag tagtgaagta gaaaagaaaa ataattcata taagaattct acttatacta
    23221 aaaaaatagg gagcagaagt agaatctcaa gtcaatgtca aaaatacaat caaaagctat
    23281 ttatggaaca agtttgtggt tatgaacaaa atgttaaaac taaagatggg aaacaagtaa
    23341 aattggttcc aaacccattt aaatatgcga cagatgatat atttgggttt atgatggcgg
    23401 aaaaattatc tatagaagaa gatgtataca aagaattatc agatgaagaa aaagaaatat
    23461 ataaaaaaaa taaaaagaaa tatgaagtaa atataactaa aaaaagaaag tcaagatggc
    23521 aaatgaactc tttaataaat gtatcaaata gaaaagttga atgggagtgg aatgtttgtg
    23581 gaactacagg agatagtatg ccatatcaag ttgaggtata ttcaggggta catacaaata
    23641 tagcaaatct taatatagga aagataggag aatatgatat atctgatata gcaagtgagc
    23701 atagagatta tacaacttta gaagctaaat caattggagt tgaaaagtta gataaagaag
    23761 aaaagtttaa aagaatagaa gctctcctaa aatcactaga atacttaagt gtagaaggta
    23821 ataagacaaa tcatctaact gatacaaaac ccaaatttgt tatattggga gagtattcat
    23881 ggggaaataa tgtatttcag ggtattatca aagaaaatgg cttagatgta gagatgttaa
    23941 aagaatctat agaacaaaat gaagaattta gaaaaagcga tatatggatt ggaataaata
    24001 aattttatga tgatacattt aatgagatag aagttaataa tgaaaaggaa caaataaaga
    24061 agtatttaga agaagagttt gaagagtatg attttatgaa aatatcaaat gtacatcaag
    24121 cttttgaaag ttacttaaaa tatttaaagg agactttata aaggatatat catgaataat
    24181 ttatatgaat ataaagctaa atcagatggg acaagtatag ataagcataa tgaagatatg
    24241 aattacataa tgaatcaatt agttagcata tataatatat ctaatgatat gaaaaatgat
    24301 ttatatgagg caattgtatg tcatgatgta gggaaagtag taaaaagctt tcaagataat
    24361 attgaaagta gcacaagaag agttagacat gagttattat cagcaagtat taagtattta
    24421 aatagaggtc agaagttagc tatattaacc caccataaag atataaagtt tctagagggt
    24481 caaataacaa attctattta tgaaattgaa ttaaaggaat taaaggaact attagatatt
    24541 gaagtagaag atataagacc atttataaag gaaatatcaa gagcaagaaa tgatgatact
    24601 agaaaacttg aaaatatatt attaaaaggt tacttgcaat attgtgacca tatagcttct
    24661 gcgggaatta aaagtataga taaaggattt aattctatta aagattttag tataccaaag
    24721 ggtgtaagtt ataattcaat acaagaaaaa gttttaaata tggataaaaa tgaagatata
    24781 atgataatgg ctatgacagg tcttggaaaa acagcaacat cattgtattg gagtaaccta
    24841 gttcaaaatg aatataaaag taagagagtg tattatatac ttccttatac agcaagcata
    24901 aattctttat atgaaaattt atataataga aatataagcg taagtatgtt acacagtaaa
    24961 gctccatatt ttttgaataa aattagtgat gaagaagata taaaacaact ttaccagata
    25021 tacaaaaaga gtgtaaaaca aattaatgta tgtactatat ttcaattagt aaagtcagta
    25081 ttttcttgta agagatttga aatgctacta tcacaattaa aagatagtat atttatagtt
    25141 gatgaaatac attgttttga tacaagagta ttgtgttata cattggaatt tttaaaatat
    25201 ttaaaagaaa acttaaatgt aaaaatatgt ataatgagtg caagtatacc aacttgctta
    25261 aaaaagttaa tacaggaaag attgcaaata agtacaatta ttgaaccaga tagtaaagat
    25321 ttaatattta gacatagatt gaatagatta agtgaaggaa tacttgatag catacataaa
    25381 atagaaaatg atttaatgca aggaaaaaga gtattaatat gtgttaattc agtagattta
    25441 tctcaagagt tatatggaag gcttcaaaaa tataatccta aattaataca tggtcgattt
    25501 aatactagag atagagagca ggcagaaaaa gggatagaag aaagcttctt attgataggt
    25561 actcaaagta tagaggtaag tttagatata agttatgatg ttctttatac agagttagct
    25621 cctttagatt cattgttaca aaggtttggt agagtaaata gaaggggaga taatgctgag
    25681 ttgagcaata tttatatata tgattatgat agaaagctta atatatatga tgaagatata
    25741 ataaatagga ctgatatagt aatatcagat ataatacata atgataattc tatagttgat
    25801 gagagtaaag ttccatctta tttagataat gtctatttag atatagatat ggataaatat
    25861 aataaacata aagttgcttt agagattata atgaaaaata tgaggttagg ggtatggaat
    25921 aaatctgcta ataatgatat gttaaataat gatactatta gtgttgtgcc tgaatgtctt
    25981 ttagaagagt acaagttgta tattgataaa aaaatgtatt tagaagcgag ttcattattt
    26041 gtaaatgtat ctgtaaaaag atacaattat aataaaaaga tgttttatga atgtggagat
    26101 atagttgtta caagttatag ttataatgat aaactaggtc taatatttga ttgttaagag
    26161 aattatagta taactaatta aaatatttta ttgagaattt gttataattt atatcgacta
    26221 caaattttat atgttacaat agaataattt tgcagtgagc gaaaaatatg tgtaaatggc
    26281 tgtgagttag tgatggcaag gtttataact gaatttttgt ttttagctaa aaacactact
    26341 ggtgcctcac tgcaaattaa ctattttaat aaccctacaa gtgttgtaat tactatagtt
    26401 ttatttgggg tttaaattac actaagttag ttataaatat tccggaaagt acttttgcta
    26461 tttgattcat tctacccgtt taaattacac taagttagtt ataaatttca ctaattttag
    26521 ttacaactat tacaagtcca gccgtttaaa ttacactaag ttagttataa attatgtgta
    26581 atgtatttta atgttttcta gcaacaatgt ttaaattaca ctaaattagt tataaatttt
    26641 ataaattcta tgaataattt taaagagagg tttcgtttaa attacactaa gttagttata
    26701 aattgtacat ttgacataga agcttcaaaa tccatcccag tttaaattac actaagttag
    26761 ttataaatgt aacagcacga atgatggcac agacctatct gcaatgttta aattacacta
    26821 agttagttat aaatagaagt acacttacaa gtaagataaa agacccaggt acagtttaaa
    26881 ttacactaag ttagttataa attctgtagc tatatgtgga agtaatttta gtagagaggt
    26941 ttaaattaca ctaagttagt tataaattat tgaaggggtg agagttgtga ctaggcacta
    27001 caagtttaga ttacactaaa ttagttgtaa atttacttat tcattaagaa acttaactga
    27061 gagtttgatt tatattattg aattagcaag agttttagaa agtagaaaat tataccccaa
    27121 taatacccca accacaaaaa taaataataa aaaatatcca aaaaaattag tataacatca
    27181 taactaaata gctatatacc tacacttacg aaaaccaaca aaacaatcaa ataaccactt
    27241 gtagactccc ctcgtctcca ccaattttga aaatgaaaat aatagaataa aaggaattac
    27301 ttatgtttgg actaagtaat tccttttatt ttgcttaaaa gcacacaatt agcacacaac
    27361 tagaaggtta tataaataaa aaggctgtcg cactagaaaa tagtgctacg ctcttttttg
    27421 tataaaaaaa taaatcccaa gttcaaaaga acctgggatt cttgtataat aactgtatgc
    27481 taaaacaaaa tactacacaa attgattata ctacttatgg tgataattat caatttaagc
    27541 taccactaaa tattgattac atgattccaa aagatgattc tgtaaggtta ttaagttaaa
    27601 ttattgagga gatgaattta gaaaaattat ataagactta ttctcgaatt agatgaaata
    27661 gagtaatcca tagacaattt ttgaaagtta taatatatac agatatgaac tgtatttatt
    27721 cttcgagaga aatagaaaga acatgcaaaa gagatattaa ttttatgtac cttctaggcg
    27781 aaacctccac tccagaccat tcaacaattg caaaatttcg cagtatacat ttttaactaa
    27841 taggcaaaag cttgattgca cagtttacaa actttcttgg agataataat gaaatttcaa
    27901 aagacacaat atttattgat ggtacaaaaa tagagtcatc tgctaataga tatacttttg
    27961 tttggaaaaa agctgtaaat aaaaatatgg ctaaaatggt gaataatata tctgacttca
    28021 tattgaaatg tgagattgat gttggcatta aaatagttta tgaagataaa attaaaatct
    28081 atcatttaaa gaaactaaaa aaaatatcaa aagaagcaaa tgtagcattt attcatggaa
    28141 aaggaaatag aaaatctact aaaaaccttc atataatggg tgaacgaaat agttgttcta
    28201 aaacagataa cgatgaaact tttatgagaa tgaaagaaga tcatatgaaa aatgggcaac
    28261 tgaaaccagc atataatata caatttggtg tagattaaga atatatagtt tggctaaatt
    28321 caggaaatca aactgctgat actacaacat taataccatt tttaaaatct atagaggaat
    28381 atactaagtt taaatatcct aaagtaatag ctgatggtgg atatgaaagt gaataaaact
    28441 atgcattttt agagcataat aatcagttat ctttcataaa acctgcaaat tatgaaatta
    28501 ttaaaactag aaaatataaa acttatattg gatgtattga caatatggat tatgaagaag
    28561 aaaataatta ttatatttgt acaaatgaga aaaaactatt tgctaataaa ataataaata
    28621 ggaaatcaaa aacaggatat aaaagtgaaa taacatgtta catttgtgaa gagtgtagta
    28681 attgtcaata taaaagcaat tgtattaaga gaagtaatag taaggttcct cttaaaaata
    28741 ggactaaaaa cttacaagta tctaagtcgt ttcatgaaaa aagaaaagaa aacttaaaga
    28801 gaattatgag cctcgagggg gatgaactta gagtgaatag aagtatacaa gcagaaggag
    28861 ctttcgctca agtaaaataa aatatgaaac ttacaagatt tttaagccaa ggtaaagaaa
    28921 atgttttata aggatatatt attgtggcga tagcttataa cgtttctaga ctacacaata
    28981 aaatagtaaa aaataaacgt ggaatatatc tttatcattt aaaaaaatat tctaaaatta
    29041 ttatttataa tcaaatatta tctgaaaaaa tggtattttt atatctttat ttgtcatgca
    29101 taattttact tagaacagaa actttatata aaacaattga aaatatacct attaagataa
    29161 ttagaaaaga gctctcacag aacaaattta atttgctcat gcaacagccc catattgata
    29221 tacatttagg ttgtataatt atacatttca atattacatg ttcattagga taatagttag
    29281 taaatgatat gattgagaga atagatataa taaactaatc tagtcctgta ttgcaatgtt
    29341 tattaaagaa tatattttta aagatccaag tactgcatct cttccagaat tgagttggtt
    29401 aatagttttt tgatgctatg caatttataa taaaaagtat aatgatttag ttgatgaatc
    29461 atcagaattt ataccctcaa agattaatca gattgcaata aaaataatga tatattctat
    29521 agttataata tctattttct ttgcaacccc tcatacaatg aatataaata tatcaaactt
    29581 ggatatgggt ataattctca tttcagtttt atttatacag tttttatcta aattaatttt
    29641 gtatgtatat tttgataaaa gggagatatg taactaagtg gtaatattgg tgaaaacaaa
    29701 aattaaagaa tatagaaaaa aactccttat gacacaaaat gaacttgcta aatcagttag
    29761 ggtaaggtgt gagactattg tacacttgga aaatataatc cttctttaaa gttagtgata
    29821 gatattgcta aagtattcaa tactacagta gaaaatttgt ctgaatttat tgaagaagga
    29881 tagtggatag attataaata gttataagat ggttaatgaa atatagttac ttaattatta
    29941 agtgtgttag aaatatttat atgtaacaca atgtgtagtt aagattacct tatctcatct
    30001 aagactttaa tttttcttcc cataaagagg gtatatcaat tttctagtgt ggtagcccat
    30061 tttttattga tttaaattta taatatatat taatagatga tacttaaaaa ttttataaaa
    30121 tatctaagtt gtcataaata aaacgatata tctaaccgaa tatggtaaaa tttgttataa
    30181 tatagataag ttagagtaaa aataatttta atgggggaga aaatgcagtc agtaatatgt
    30241 aaaatttttg ataataaatt actaattagt aatgatttaa gtgagcagga tgatgtatta
    30301 tatgaggtaa tggataaatt tatagatgat attgaatata tttcaaaatt aggagatgag
    30361 caaattaaaa gtatgcttat ggaggtaaat aaatttgaag aagattcaac tgaatttgaa
    30421 ctatatatga aaaacttatg ctatttaaag caatcatatt ttatagatac taatgataaa
    30481 agtgaaataa attctataga tatagatata ttaaaaaatg ttaaaataga ggacttagtt
    30541 gatataacta atattaaatt agaacgaaat ttaaatataa atatagaaca tatatctaaa
    30601 gctgtaaata aaatatatga agaaaatgaa aagtggaaag agtataatat acaaaatact
    30661 atgtctaaat atataggtat acctgaatca gaagttatat ttatatcaaa tttgagtcag
    30721 tatgtttcat ttttatctga actagataac gcaggcgact atgtatctag agggcaaaaa
    30781 gattgtatgt atgaattatt accatcatta catagaaaat ataaaaaaga ctatggtata
    30841 cattcagatg aatacgagga agcattcaaa caaaaaataa tttattatga taaagaaata
    30901 aaaaatagat cgagtgaaga attaagagct gaagggcaac attttggact accaacagaa
    30961 tatttagatt tcacagaagc tcatttaata tcattattat ttgcaataga agactataaa
    31021 tatacaaaac agcattcaat tgtgtacttt atagactcta tttcttataa tactgacact
    31081 ataaaaagat ctgagaagtt agtaaattat tcagatacat ctgcaataga taattgtagt
    31141 aaattttcat caagatcatt ttttataaag gtagggaatt caaatgaaag aatacatttt
    31201 caaaaaggat gtttcctaaa agtatcatca gaagataaag gcgaatttaa ggaaaaatta
    31261 aaaaagtatt gtaaagtagt agttattaat aaagatgcta aaaaagaaat attaaaagaa
    31321 ttatttaatt taggtattac atttgaaaat atttatccag ataaagataa tgtagttaaa
    31381 tctataaaat tctattatga tgagatagta gggggaaatt tataatgaga gaacaattta
    31441 aaaattctat aaaaaatatt aaatcaaaca gacctcttgt atcagtccaa gatattgtga
    31501 attttattga taaaggagaa aagtacttga aattatcaat agatgaaata gatgaaatgg
    31561 aaattttaca aggaatagtt atgagtcctg attatcaacg tacatataaa tcatcaaaca
    31621 aggaagaaag ttctataatt gaatctcttt taattggaat accaatacct gaaatatttc
    31681 ttgtaaaaat aggtgtaaat gatatgcaaa taagacatgt aatggatggg cagcatcgtt
    31741 tgaatgctat atataggtat gttaagaata aatatccact taaaaattta gatatattag
    31801 gcaatgaccc actatatgat aataaaaggt tttcagaatt agagaaaaaa gataaaatta
    31861 aaatattagg aagtcattta tcaattctag aatttgatgg ttttgataat ccagaaatag
    31921 aaatagaatt atttaaaaga tataacagaa atacaaaacc attagagatg caagaaatcg
    31981 agatggcaac atatttttca gaaactagta agtatataag taaatttata aatactctaa
    32041 taaaagataa atataaggat gaaatagata aatcagaata taaatatgct aattacaaat
    32101 cagatttact tagaatatat aacataacta aatctcgtaa tgataaacaa aaaaatcatc
    32161 aagaaatatg tataatattt agtattttag aaaatgggct acaagaaaat atcagagatg
    32221 gagttacagc ctctaagaaa tttttagagt ataagtcaat tcagtataaa aataatgaaa
    32281 gtgaaaaatt agagttatta aaagataagt ttgatgagtt taataggatg atactgaaaa
    32341 tatctgagaa gatagaatat ccattctcaa caagtttaat atctgatgat aagcaaagac
    32401 aaagtaaata cttgatagga gtatctattg tgttggcttc tatttgttat tattatgata
    32461 tagacttgga aaataattat ttaatacaag atattaaaaa aataatatct tgttcaccca
    32521 tagcagatat agaatataag gcgtcttcaa ctaatatgaa aaatatgatt ctatacttat
    32581 ttataaagaa taaaatacaa gataataaat ttgaatcatt aaatttaaaa agagataaaa
    32641 ttaaagaaat aaatacttta gtaatgaata atgatggtta tttaaatgaa cagacaaggc
    32701 tattagaaat atattaacaa gttataaaat aaatcatggt aatgtaaaat aatttgtgct
    32761 tttaaggtta ataaaaatct tctttatggc aattatttaa atataatcaa atgtcgtaaa
    32821 ggagattttt tatgaacgct ttaagaaaac aattagccaa agaaattata tcagatatct
    32881 aaaaaagagc atgtcaaata aaaccctagg tatttaaatt tttttagagc tacttaaaat
    32941 aaattatgct atctctgtat ttaaatattt cctaaattca agtggagaca tagaatttaa
    33001 tctcttttga tatctaaaat tattatagta atatatataa tcctctattg ttttgactaa
    33061 ttgttcgtat gtatcaagtt ttcttaaata gtacatttcc acttttaaaa ttctccaaaa
    33121 tccttccata ggagcattat caatacaacg agcaactctt acatactttg tatcatgcct
    33181 tgtgttaaaa gttttgattt aaatacctta ctagtatact ggaaactttt atcattatga
    33241 aaaataggtt ttgcatttgg atatagctct attgctttat caaaagtttc taacaccaag
    33301 ttattgttat ttgactttcc aataacatat gaaactatac ttctatcgtc taaatctaga
    33361 attgcgctta aataggcctt catcccattg gttaatttaa attcagttac acctgttaac
    33421 catttttgag aggttttatc tgcactaaat tttctactta atacattttc cgcgatcact
    33481 tctggcgtac atttaacata actaaatttc ttttttctgc aaacagaact taagcctacg
    33541 gctctcatta gtctgtacac tctctacaat ctttaacaat ttcaactctt tcatctaatg
    33601 ctgtttttct agtctccata aagatttctc ccttcgaggt ttcttttatc tacttatgag
    33661 gattatactc tttaccccaa gcttttagtg aataaactga tctcatttta tatttttttg
    33721 agattgtgtc ataagatcct tcaccattta gataagattt tatagcattc aatttaaatt
    33781 cttcacaata gcataattta caactttgtt ttattaaacc atcatttcca aaagcttcat
    33841 aatttcgcat ccactctctg aatgtacgtt tatccaatat ttaattcttc cattattttt
    33901 attactgtat tctcaccttt taaatatgat tcaattgctt cgattttttt gctctgaaga
    33961 tatcttagtt ttagatagtc ttacatattt taactgtctc ctaagatgag tataattcat
    34021 tcatcatcag ttctatagaa tacacctagt tcctacttac tgtaggaact aggactatat
    34081 gaaacccatt catagattgt agtttcttct gttgcattat agcgcagaat agtaaattca
    34141 tgtgaaattt tattttgaat ttactattta tatataaatg aagagtggtc ttattttcaa
    34201 ttaaaatttg gaacaatttt gggttgacat ctacaattaa ggatttaagt ttttgttata
    34261 ctaataaata aaaacagaga ttcaaaatat ataaataata cttaaactag tgctgataga
    34321 ttttctttaa gttctagttt ttttattgtc attatctaat atgtactatt ttatgtacag
    34381 tcaatataat ctgaaattgt aaaatggtgt ataatatagt tataagtaaa gaagggattt
    34441 aaacatgtat gattacaaaa ataaaaaaga cttatatata ccttaaggaa atacaaaaaa
    34501 tatacaaaat caatgagcat aaagaactag tacacataat aaaaaaacta ataaatgata
    34561 ataaaataaa accaataaaa acctcagatc taacacctca gcatgagcaa ttatatacaa
    34621 agtatagaat aataaaacaa gaaacagaag aagataaaaa aatattagaa gaaataaatt
    34681 acaaaatatg tgataaatta agtatagatt attatagaaa aaacttagta cactataaaa
    34741 ataatagagt tgcaataatg gatttaaata gttatcttat taaaaaatct gataatctat
    34801 caaagaaaat atcgattaac gaaagatctt atgaaatatt taaggatgag aaattcataa
    34861 gtagtaaagt aggaaaagaa gtactaaaaa acttaaaaat agatctaata aaggatttaa
    34921 acgtatataa gacaccagag ccattcatat atttatcaat aaatcgtata tctccacaaa
    34981 aaatattaat tatagaaaat aaagacactt acataacaat aacaaaaatg ctattagaag
    35041 gaaaagaaat acttaaaaat aaaatagata ctgttatata cggagaagga aaaaaaataa
    35101 tcaacagtat taaaggatta aaggaagata taacaattga atatcttaca aataaagaaa
    35161 atgaattttt atattgggga gatatagata aaactggatt atcaatatac acttccctaa
    35221 aagataccaa tgaaattaat aatataagat tatttgaagt tgcttatgag catatgatag
    35281 ataaaacaaa ggaaaatacc ttgaggaata tccccaaaaa tcaaaaagat aattttgaat
    35341 gtggattaga aaatattaat aacctaaact taaaagaaag tattaaaaat attttagtac
    35401 aaggaaaata catacctcaa gaagctctaa atagattcga cttggaggaa tataactaat
    35461 ggaaatgatt aatattttag aaggctacaa taagagagta aactgtatag gatcttatta
    35521 tcttattgca actcttgcta acaatagaaa taaatttaaa gaatttgaca acattcaatt
    35581 ttacaattta ttaattcaag ttttgtgtta tatatttgat agatctctta gaagaaagaa
    35641 ctgtttaaga gatgatatta aggattttat tgaagaaata aatcgtatgg attataaaat
    35701 aatgctttca gaggatgact taaaggattt agcaaactat ataattaatg gattaaccaa
    35761 tagtggtaaa gtatatctat ttacctacta ttctttagaa caagaaaaac atatagatga
    35821 aagtattaaa attatagaag ataaaaatgt aaaaataaat aatcaggaaa gactatccta
    35881 ctccttaaca acagagggtt atagattgtt gttatcaaca aaagaatatg atgaactatt
    35941 ccaaattcaa atatcacaaa tgattgcaaa gttaaggata gaaaagggtg attatcaagg
    36001 cgcaaaggaa gatatttacg atataataaa taccttagag attcatcaac agaaaattga
    36061 taattatata aaaataataa aagtaaatat actatatata aaagaagaaa aatattcaac
    36121 agtaatagat acaactgtag aaacactttt agaagaaatg gacaaatatg aagaattaaa
    36181 aaaagaagta aaactattaa tcaaagataa agaggactac ttggaaaagg atgaggatat
    36241 agacaaagaa aagataaaaa atataagaac tcaactatta caaatgaaag aattaataga
    36301 tggaatagtt ttagcaaagt ctacagccac aaatttgtta tctagagttc aagattttag
    36361 agaagaattt aaagaaatac ttaaaaaact attaacaact ccagtaatta aaagattcaa
    36421 tttcaaggaa gaaatcttag atagacttga aaaagacagt gattttttat tgataataag
    36481 agaattatat atatctttat ttaaagtaga gttgccaaat cgatttaata ttggagtggc
    36541 atatcaagaa cagaaactat taaatactag agaaattgaa aatgaaatag ttaataaaga
    36601 cgagttagaa attattgaaa ataaagagaa ggaggaacgt ataaattatt gtgaaaatta
    36661 ctattttgat ttttttaaat acttaattaa atatggactt gaaaaaggac aatttacatt
    36721 agaagaattt ctaaaaaatt atctgaaata tgacaaagtt atttacttag aaataactaa
    36781 agactccaaa ttgatgagag atataataat ttacttcgct aatcaaaggg aaagtatcaa
    36841 tatcaaaaag ataatcagaa tgttagaaaa tagtgccttc tcaccaaata cagattttca
    36901 aattgaaaga ttaatagaac gtttattagt agaagatttt gaactattaa atagcgttag
    36961 ccatattaaa agtaataaaa tatttgaaga tgaaatgaaa ataaatactg aaataaattt
    37021 agaaactatg actgcagtta agctagaaat agcaaatata aaatttgaaa taatctaaat
    37081 ataaggggaa atacaatgaa tatatcttta aatgactata aaatagccaa tgaaatattt
    37141 tatagattac ttaaaaaaag tgagttaaaa gaaaaagaag ctaaagaatt atttttagct
    37201 tatataaata acagtaatgt aaggtatgct ttagaggcaa tttgtgaagt atctaaaata
    37261 aaaataatat taatttcaga taccttatac ttaataccaa ataatgacaa tgatattttt
    37321 gggtttgact atagaagaga atctttatta gggaaagatt taaaagatag ttatttagga
    37381 tatttgataa tgacaataat attttctgaa tttacaaatg gggtagcacc agcatcatat
    37441 attcaagtat taaacttact ggatttagta caagaatcct tagaacgttc aatagctcgt
    37501 gataatctag aagaaataga aaaatcatgt gagtttaata taactatctt aaagaactat
    37561 tgggaaagta aaagaaagtg ggacgaatct agtaagaaag gaatagaaac aacatcagca
    37621 gatttccaaa tagggtttat tagaaaaata attaatttct taaaaaatga aggcttaatt
    37681 gtacacattg aggatgaaga taagataaaa ccaactagaa gatttcttga tcttatgaat
    37741 aattattttt tagatgaaga aaggaaagta ttaatagaaa aactagtttt aagaaaaggg
    37801 gaaagtatta atgccagtaa ttaataaata caaaattata aattttaaat ttggtatggg
    37861 acaagaaaga atacttagca acagaaccat ggaactgtat ggagaaaact tacaagtaga
    37921 agcagaaaat acagcaggca aaactatgag tattcaaact atcatacaaa gtatttgtcc
    37981 actatcggat gtagccaaac cgtttactgc aatatataat aaaaaagaac cattatactc
    38041 aatgactgaa tggttgctag atgatggtaa aacgttatta ttaacgggaa taggatttga
    38101 gaaaaaggct ggatcatcta aagaagaagg gaaagaaaaa aaggacgatt tatacaaata
    38161 ctttatgttt attatagaag aatctaaaga aatggaggtt gatatagata atataccttt
    38221 attaaaaaac aatgacaaag gtataaggat agtacaacct ttaacggcct cacaagacta
    38281 tataaaaatg ctaagagata aatatggaaa aaacaaagta cacttcttta ataattactt
    38341 aagaaaacaa catagagaaa aattagaaga atatggaatt aaccaaagtg aatggaaaga
    38401 aattattata aaacttaata gtaataacaa agaaggtgga ctatcagact ttgttaaaga
    38461 acataatact tcagaaaaac ttataagaga taaaatatta cctttaatag agacaagctt
    38521 aacaacagaa gaattcgctc caatattgca aattaaggaa caagtaagaa agtgtataaa
    38581 taatattata gacatgaatg aaaaattatc agattataaa aactatagag atttaaacat
    38641 tagagttgaa agtttacaaa ataaaataaa taggatccta ttcatagaag aagataaaaa
    38701 taatgtatta ggagaattag ctaatctata tgtacatata gaaaataaac gcaatgaatt
    38761 aaatgaagaa ataaaacagt atcaaaaaat gaaagcatca aaagaagagg aatttaagat
    38821 agtagaatat gaagaagata gctatgagta ttttagaaaa gaaaaagaga tacaagatac
    38881 tcaggtagaa tttgataaag ccaaaaatga attaaatgat aaaatagaag aactagaatt
    38941 agatgaacaa tatttaaata tatcaaagtt caaaagaaaa aagaaggggc tagaagaagg
    39001 ggaaaaagat aagatagaaa aagaaagtga aaaacaaaga aaagaggtaa atcaagaaga
    39061 aataacggct attataaatc gtctaggtag cagtattcat tattgtttaa aggaagaaag
    39121 tattataaat aatgaaaaac ttaaagaaaa tacaaacaac aatatagcta tacaagaaaa
    39181 aaagaatcaa cttaatgatg acaaaagtaa gctcacaaaa gtattgataa gtaaaaattc
    39241 agaaattaaa tatatagaag gcaaagaacg tgattttaat aatcaactac atgaatttaa
    39301 acttaataac actgatatta aaggctttat ttctaataat tttttaggcg aagtaataga
    39361 ttatactagg tatataaatt atttaaatat aaaagtaaaa tcaatagaag aaaatcttga
    39421 atcgaaagtc atgcaaatag aagaatcgaa taaacttaag gatgatataa atgaagctat
    39481 aaataatctt aaattagata atcatgaatc ttatatgaaa ctgcaagtat taaaaactag
    39541 aaagaaagat atagataatt ttaaagaaaa atataaaatc attaaaacaa gatttgaaat
    39601 agacaatgaa ttagataact ctactaaact atataaagag gtaaaacaag agcttaacaa
    39661 aatgaaactt caagtacagg acttagaaaa taataaaaag caattagaaa aagagctaga
    39721 agatttacaa aattataaag atataatttt cgaagaagaa atattaacag atctagaaag
    39781 aaatggaata aaacctattg aaggcatgaa atatctatta accttagatg gagatttaga
    39841 atacaaaaat aatctcatat ctaaaaatcc attgctacca tattctataa taattacaaa
    39901 taaagagtat caaaaactga agcaaataaa cttaaaaaat aaaactaaaa tctcaatgcc
    39961 tatatttgta agagataaca tagaagatac ttttataact acatctagta accttgtaat
    40021 tagtaatgga ttaaatatac tatcttcttt cgataacaaa gctttagatc ctgaaaaaag
    40081 agaaaaggat atgaatctaa tcaaagaaca aataaatagt attcgagata aagtggagca
    40141 atataaagca gaaattgaaa tattagaaga atttaaactt ctaactaata aaattgattt
    40201 tacagctgaa gacttatcca tagatgtgaa aattgaaaat tataaaaaaa ttatatttga
    40261 aataaacaat aaaattaaga gtaatgaaaa taatgagaag aatttatcta ataaaattaa
    40321 agaactttac gaaaataaag aaaagctatt aaataacaag aatatattat ttaataaatt
    40381 gaaggacatt agaaatatac aagatacata ttctataatt ttagaaaata aaaatgaaat
    40441 aactaagtta aaaacaagta ttgaaaaaat cgaagaagaa aaaaaagtta ttaaaaaatc
    40501 aatagaagat attgatgtta atatatttaa tttaaattca gaaaaagata ggataaatag
    40561 gcatatagat gatacagaaa gcaagataaa taaatttaag atttatgaac ctattaaact
    40621 tgaaaatgct aaactagaag aattagaaat aaaatacaag aaatacttag aagaccctac
    40681 aaaaaaagag attgaaacat taaattatga aatctcagtt tgcttaaaaa gaatagagag
    40741 tattactata gagttagaag aatttagaca acttattagt agtgataatt ttgaaaatat
    40801 acctatatta ttcacaatag aagaacttaa taaaagaata gttttaaata aaagtaaggt
    40861 tgatgaacta cgaaaactta aatatagtat taaaagcgac atagataaaa atcaaggttc
    40921 attaaacact aagagggagg agatacttaa aaaatttaat ggaaaagaac ctttatctac
    40981 tagcttaata gtgaacttta attttgaaga aagaaaaata gatataaaaa aagatataaa
    41041 ggatattggt gaaattatag aaggtaatag aactacttgt caaaatctag aacaggaatt
    41101 aagagactta aagaaatata aagtagaaag aaaagctata acctatcaac ctgaagatat
    41161 ttttattgaa agtaaaaaac tacaatcaaa actgcaaaat gttgaatata atttaattaa
    41221 atctataaat agctataaaa atacaatatt agaaataaaa gaatttaatt ataagcacat
    41281 ggaaaaatac aaaaacttta tagaaacttt aaatgtaaat aaagataatt actctcgaca
    41341 aaaagaacaa gtagaaatag tattactagt tataagagaa gaaataagca aattagaaaa
    41401 acatagcgaa caactaagaa aagaaaagac tataatatca aggcaaataa aagattatgt
    41461 tatggactgt attgatgaat ttaaaatcat aaataaactt ggtaaacata aaggacaagc
    41521 cttattcaac atatcactac ctaaatctga taaaatagaa aatagtttga gcttagtaga
    41581 tatgctaatg gatgaaattg tagaagaagc aaacctaggt gatgttgaac aaaaaataaa
    41641 taccttttat attttaaata agactcttaa tatagggaga attcctgtat cagttataaa
    41701 atatgaaata aatagaaatg aaactataaa gtggaactct attaataacg aaacaacagg
    41761 aggacagaga ttttgtatct catttattgt gacaatattg ttgatggaat ataaaagata
    41821 tgatagaaat gcaatagttg atgaaagtaa atataagggt aaggtactac ttatggataa
    41881 tccttttgga gaaacgtcgc agcaagattt ccttaaagaa atatttgaac ttgctaaaaa
    41941 attcaacgtt caaattatat cctatactca tgtaacaaat gcttctataa gagcaatgtt
    42001 taataagatt tatttaatga cagttgaaaa aactacttct aataaagaat ttgtggatat
    42061 taatgagatt aagcaaaata aaactgatga attggtgtat atgagtaaat tttatatagg
    42121 taataaagaa gaattaattc aagaggatat atttagttta atataaataa caagtaaaca
    42181 aataaagtga ttactatcag tgaggcaggt agaaactgaa ttactttgtg actcattacg
    42241 actcttgggg taaaattgtg tataaatgtg aagaatttcg tgattgtcag tacaaaagca
    42301 gctttattaa gggtaataat agtaagactc ctcttgaaaa taggactaaa aacttacaag
    42361 tatctaagtt atttcatgaa aaaagaaaaa ttaaagagaa ttataagacc agagggatgt
    42421 gaacttagag tgaatagaag tatacaagta gaaagagcta tcgcagaaca aatttaattt
    42481 tatcatacga tagcctcttg ttattttagt gatgaaatcc atcaagcata ccataactac
    42541 agaaaaagag gcttttctga tggtatattg ggttctttta gagtgtgtga tttgctacat
    42601 gttcattagg ataataatag tcagtaaatg atattactga tagaatagat ataataaact
    42661 aatctagttc catattgtaa tgtttattaa agagtatact tttatgatta taatagctat
    42721 tttctttgaa gcttattgta caagagattt gaatatatca aatttggata taggtataat
    42781 tctcttagca gttttattta tacagtcttt atctaaatta gtgttgtata tactttgata
    42841 aaagggggat atgtaactaa gttgtaatat tgatgaaaat aaaaattaaa aaatatagag
    42901 aaaaactcct tatgatacaa aatgaacttg ctaaatcagt tggggtaaga cgagagacta
    42961 ttgtacactt agaaaatgga ttaatgtacc ataaaggtat ccaagataaa tagttaaaaa
    43021 actagataag aataaggagc ctttacagaa caaatttagt gtgctcgtgc gatagccctt
    43081 tttttataaa aattaatcta ataacctata taattaaatt tataaaacat atatgaaagg
    43141 gtaaaactat atggctaaaa ttgataatat gatgtccata ttatggatgt taaactcaga
    43201 caaaaaagtt accgcaaaac aaatatctga aaaactagaa ataaatataa gaactgtcta
    43261 cagacacatt gatgcattat ctgctagtgg agtacctata atttcagata caggtcataa
    43321 tggtggatat acacttttga ataatttcat caaagcacct ctttttttcg atacagaaga
    43381 acaaactgcg ttacttcatg cagctatatt tgctaaagaa gagggaagtt tcttagatga
    43441 cacactagac aaagcaacct caaagttaaa aatgtattca aatcaaaaac aagaagaaac
    43501 tttaacaaaa catttaatag gttttgaagt aataaaacca actggaaaaa tatccataga
    43561 atctgtactt aaaaagttaa aaaatagtat agcaaatgaa ttatctgtag aaatcaacta
    43621 tcgtacagct catgaagaaa aatcaaaatg taggattata aatccatatg gaattgtacg
    43681 ttggaataat aattggtaca tagtagcatt ttgtcaaatg agaaatgaga ttcgtagttt
    43741 tagggtagat agaattagta gtgtcataga aacatcaaat acttttaata ggccaaaaga
    43801 attttcagca agtgaatttt ttataagagg gattatggat gaaacaaaag atgaggataa
    43861 tcttatatca ttagttatag aaggaaagat gaatgcattg gataacttat gtcagcattg
    43921 gcttctagga tattatttaa aagaaaggac ttcaaataaa gcaatattta aacttcaaga
    43981 agagataata tttacatatg taccgaatat acttatacct tatagaaaat ctatacaaat
    44041 aattgaacca ttaagcctta gggataaaat ggttgaagat ttactcgaat taattaatca
    44101 ttatcaaatt taataactta actgacagag tatgtcagtt aagttatttt acaattaggt
    44161 atattaatta attatagaag gagcaaaaaa atgaaaaaga gaaaagtata tatgtatgta
    44221 ttcgatacta tgtcagattg ggaagttgga tatctaactg ctgaattaaa tacaggaaga
    44281 tattttaaaa aaggattaaa accactaaaa gtaattacag taggagttga taaaaatcct
    44341 attataacaa tgggtggatt aaaagtttta cctgagatta caattgacga gcttaatatt
    44401 gaaagtaatg acttattaat tttgccaggg ggaaatactt ggacatctat aggtcatgag
    44461 aaaatattag aaaaatctaa agaggctttg gaacaaaggt ctatagttgc agctatttgt
    44521 ggtgctactt tagggttagc taaaacaggt ttactagatt ttagaaatca tacaagtaat
    44581 gatttagaat ttttaaaaat ggtgatacta agttattctg gagaaaaata ttataaaatg
    44641 gaatctgcgg ttaatgatga aaatttaatt actgcttctg gaattgcacc attagaattt
    44701 acagtacaag ttttaaaagt tttagatgtt tttaaagaag aagcattaag ttcttggttg
    44761 aacctttata agacgcatga ctctaaatat tttttcgaac taatgaattg taataaataa
    44821 atttaagatt taattttaaa ttcaaatttt aaattacttt ttctatggca atagataagt
    44881 agtttagaat tttatcatat atataatttg tatttatacc aacacaaata gaaatgatag
    44941 ttccaataat aaaatttata attagttcca tatggagtac atttctttcc tactaatata
    45001 actaagaata tatgaaacca ccatagattg tagttttttc tgttgtatta tatcatggga
    45061 tagtaaagtg acgtatattt ttgatgaaaa cctaggattg tatatgaaat gaattaatcc
    45121 tgtgtattaa tcttgagatt cgtgtctaat gatttgtaaa aataaataat gaaatactta
    45181 gaaatacttg taaatgctag tcaatattgg ctagtatttt ttattttagt aatgaaatcc
    45241 ccaactgtac ttcatccaca aaaaaagaga tatttttgag ggtgtattgg agtgaactta
    45301 ggctgtataa ttatacattt caatatctta tattaattag gataatagtt ggtaaatgat
    45361 atgattgaaa caatagatat aataaactaa tctagtactg tactgcttac taaagaatat
    45421 atttttatgg tataagaatt ttttagagcg ttgattctat aggagtgaat aaaaaagtaa
    45481 ttttataata ttatttgtaa ccattagatg tctattatga aatcttttat ggactatatt
    45541 tgtaaaaata ttattaagta tttacaatat tttcttgcaa tttatttgga aaggttatat
    45601 atttataaca tgaagtgtta taaatatata acctttaagg tggattttat atgtctaaat
    45661 cagaaactgg tgtaaaatca aaactcatat tggaattact tgtaataact tatcttttta
    45721 tagctgtatt agctactaag tatattttta aaggtccaag tactgcatct cttccaggac
    45781 tgagctggtt aatagtcttt ggatgctatt caatttataa taaaaaatat aatgatttag
    45841 ttgatgaatc atctaaattt atactatcaa aggttaatca gattgcaata acaataatga
    45901 tgtattctat agttataata gctattttct ttgcaacacc ttatataagt aatataaata
    45961 tatcaaactt ggatactggt ataattctta ttgcagtttt atttatacaa tcgttatcta
    46021 aattaatttt gtatatatac tttgataaaa gggggatatg taactaagtg gcaatatcga
    46081 tgaaaacaaa aattaaagaa tatagagaaa aactccttat gacacaaaac gaacttgcta
    46141 aatcagttgg ggtaagacgt gagactattg tacacttaga aaatggaaaa tataatcctt
    46201 ctttaaagtt agcgatggat attgctaaag tattcgggac cacagtagaa aatttgtttg
    46261 aatttattga agaagattag tagataggat ataaatattt ataagattgt taataaaata
    46321 tagttattta attattaatt ttgttaaaaa tatttataaa taatataatg tatgagtaaa
    46381 gttaggttgt aattatttta agataagaag actactgtaa atgataaaaa ttagtgaata
    46441 tacagccaat taataaataa tagataaaac tttaaagctt agatgtgagg atgagatatg
    46501 gtcttacagt agttcacact tttaattaag acttaaaatg gaaaccatac acatacatac
    46561 actatttact gaaagtggac tagataaaaa aataataagt gatttaagaa agtatctcat
    46621 atactatata agtattattt taggtgacct atttataggt cattttttat gtatataaat
    46681 gataataata ctaatattta aaataggttt taaagaaata aaatatccag attgaaaaat
    46741 ggattaatgt taataaaaaa attatatgta taaaaatagg tataattata gaaaaaaaca
    46801 ataataaaat aagctgttat agaaaaatac aattatatag attgttgttg aatcattgac
    46861 tgcaagaata ataacattta aaatgaacat ggagaatatg ggggaggaat caatatgaag
    46921 agaaaaatag cagttgtttt attaactgta gcaatgttat tatcacttgt agcttgtagc
    46981 aatgataaca catcaaaaag tgataaatta gaggatacat tagtagtata tactacacat
    47041 ggagaggata tgctaggagc aatttctgaa gaatttacaa aggaaacagg agttaatgtt
    47101 gaatttataa acttaaaagg tgaactagca gaccgtgtta gaagtgaaaa agataatccg
    47161 caagcagata taatgtttgg tggagataca tctacataca tgcaattaaa agaagaagga
    47221 ttatatgaaa agactgaacc aagctggaat aatgaattag acaagtctta caaagattca
    47281 gatggatatt ggtatggaac tataaaaaca ccagtaatga tgttttataa cacaaaacta
    47341 ttatcagctg ataaagcgcc aaaagattgg agtgatttaa caaaagaaga atacaaagac
    47401 ttaatagtta ctagagattc attatcatca tctatgcgtt ctactattag taacttaatc
    47461 aattactact caaatactaa gagtgaagaa gaagcttgga agtatcttga ggatttaaat
    47521 aagaatataa agaattacta caatagtgga agtgtcatgt attcagcaat aggtaaaggt
    47581 gaagctacaa tatctgttgc agtattaagt gatataatag agaataaaga aaaaaataat
    47641 atgccattag aagttgtaga tgcagagagc ggttctgtag taatcacaga ctgtgtagca
    47701 gctctaaaaa atgcaccaca tccaaatgca gcagctaaat ttgtagattt tgttggaagt
    47761 gctaaggttc aagctatggt tgcaaatgat tttaatcgta ttccaacatt agattctgca
    47821 cttaaagatt caccaaagtg gatgtcaaaa gaatataaag ctatggatgt agattggtct
    47881 gtaattggaa aaaatcagtc taactggatt gaaaagtggg aaacagatat aatagataac
    47941 aataaaacta taaaatagcc taattaaata atttaatatt atatacaaaa atagtgagga
    48001 ttttcctcgc tattttacgt ataaggaaac tatagtatct cataattttg tataattcat
    48061 acaacaaaat gatactaata catacttatt aaataaaata gtttttgagt aactgatgaa
    48121 gtaattgact atataaagtg atttgtagac atagtctctc aaataaagtg aattttttat
    48181 tatgcaaaac ttttaattat agtaaaagta caatttatat gggcaaggag ataaaaatgg
    48241 aactaaaaat tagtgattat aaattattat gtaataaagg tagtggcgct tttaacgaag
    48301 atatcgtagg tttatcacct tatggggcat gggtacttga tggagctaca ggtttaaata
    48361 ataaaaattt agtctctaca gaaagtgatg ccaaatggta tgtaagttgg tggaatagtt
    48421 atcttcatga gaatatggaa agagaagata gcttaaaagt aattattaaa gaaggcattg
    48481 aggagataac aaaagagtac tacaaattaa cagatgataa agaagtagaa gcaatagata
    48541 ttccttcttg ttcatgttct atattaaagt tttataaaga taagatagag tatttacttt
    48601 taggagattg tactttatta gttaacaata atgaatctgt gaaaatttta aaagatgaga
    48661 ctttatgtga acttgataaa aaagtatttg attttatgaa agaagccaaa gatgctacaa
    48721 accttacttt aaaggagaga aaagccgagg taatgcgatt ataatagaga atagacttaa
    48781 gaaaaatact gtggggggat attggacttt ggaattttct aaagaggccg ttgacaattg
    48841 tgtaagtgga tttattgata tagaatataa aatgaaaatt atgatggcta gtgatggttt
    48901 ttcatgtgga tatgatagat ataagatttt tgataaaaat gaaatgatga aaatagcaga
    48961 gattaaaggt atagattata tatatagaaa ggttagggaa ctagaaaagg atgatgaaat
    49021 ggcaatagag tttcctagat ttaaaatcta tgatgattca tcatgtgtat atttagagat
    49081 ttataaatat tagataattt atggagacga tatgaagaat atagaattaa aagaaattaa
    49141 tcattattat ggaaaagaaa aagtattaca tgatattaat atatctatta aggaaggaga
    49201 gttttttact ttactaggtc cttctggatg tggaaaaacg actattttaa gaataattgg
    49261 tggatttata aaaccttctt ctggaagtat ttatgttggt gataaaaaca ttaccaattt
    49321 agaaccagaa aatagaaata tgggaactgt ttttcaaaac tatgcactgt ttccaaatat
    49381 gacagttgaa gaaaatgtat cttatggatt gaaaataaaa aagctgtcta aaaaaattat
    49441 aaaggaaaaa tgtgataatt atttagagct gtcaggaatg aaagatttta ggaaaaaaaa
    49501 gattgatgaa ttatctggtg gacagcaaca aagggtggca gtagcaaggt cattagcgac
    49561 tgagcctact atgcttttat tagatgagcc aatgtctaat ctagatatag ctttaagaat
    49621 caagatgaga gaagaaataa gagagataca gcaaaagaca ggtattacta ctttatttat
    49681 tacccatgat caacaagaag ccttagctat ttctgataga atcgctgtaa tggataaggg
    49741 taaagttctt caaattggtg tgccaataga agtttacaaa agcccattga atgattttgt
    49801 agcaaacttt gtaggtactt caaactgtat tggaaaagaa gattatgtta attttaatat
    49861 tgaaaaagag acaaagcctt atatttataa aagacctgaa gaaatgatat tattgcaaaa
    49921 tacaaatcaa agtggttttg taaaagtaaa agtagaatct aagaattttc taggagcaat
    49981 tttagaatat acagtatcaa atgatgggaa aaaatatcaa gtaactgagc ttaatagact
    50041 gaataatagc aataaattaa acgtagggga tatggcatat ttaggtgtgc tacaaggtga
    50101 ctaatatgat taaaaaaata aaccgtagta aatttacatc taaaaatgtt atttttattg
    50161 ttttatacag tatattattt tggattttga ttggatatat tatcatacca ataggcaata
    50221 cttttgtaca agcattccaa ggtaaaggtg gatattcttt tgaagttttt aaagaatatt
    50281 tttcaaatac taataattta agggtagtaa gcaatactat aattttggga ttgggttctg
    50341 tgttcgtatg tggaattatg ggaatatcac ttgccttata tatgacattt gtttgtgata
    50401 aacataagaa aatcatacat attcttttac taagtccaat gatgattcct ggagtaatta
    50461 tggtaattgc atgtattcag atttatggag aaagtggaat agttacaaaa tctatagaaa
    50521 ttttactccc ctttatcaaa aaaccttatg attttagtgg attaaaggga attttatttg
    50581 tggttgctta tactcagtat gtatattttt atttaaatgt atatgttgcc ttaaaatatg
    50641 tggattactc aacagttgaa gctgcaaaag gaatgggagc atcaaagcta agagtatttt
    50701 ttgatgtaat atggcctgtt attacacctg ctgttataac ttctactatt ataacttttg
    50761 catcagggat tagttctttc tcagctccaa atcttatagg tggtggtttt aaagttttaa
    50821 gcactcaaat tgttaggtct aaggctaata accatatgga tatagcttca gttcaagtaa
    50881 ttactttatt actaatgggg attttattta tgattttatt acagtattat ggcaaaaaat
    50941 atggagtagt gccatcctta aaatctcaaa gttataaagt tcataataga aaaaaagact
    51001 tatttacatt tgtatgtaag gttattattg aaatacaaat tattatgatt atgcttccta
    51061 tagttactat tgtgtattta tcctttgtaa gcacacattc aattatgaca accatatttc
    51121 ctagagactt tacactggaa aactatcaga tgattttcca aaaatcacgt gtattacagc
    51181 ctatattaaa tagtttcaaa atgtctttaa tggcagtagc agtaggattg ataattactg
    51241 taccagtatc atatttagta attaaaaagg atactgcata taatcgacta gcaaaattta
    51301 ttataatgtt accttggagt atgcctgcaa gcgccattgc agttaaccta attaatacat
    51361 ttaatcaaaa aagtatattt gcttttaatg aatccttaat aggaggtttt tatattgtac
    51421 ctatagcata tacaatttat gctctaccat tattattttc atccaatgag gttgctatga
    51481 agtcaataaa tttaggacta gaagaatcat caaggagttt aggtgctgga aggataaaaa
    51541 ccttttataa tgtaatagtt ccaaatatga tgccaggaat aatttcagga gctatattag
    51601 tattcattcg tacaattggg gaatatacaa tgtcagcctt gctttatggt gtttataata
    51661 gacctatttc aatttctatt gtaactaata tgcaagaatt taagatagga gtatctatgg
    51721 cttatggtgt attagtaatt ggtatatgct atatagcatt aggaataatt tttaaattag
    51781 atagaaaaag atttacataa gataacaaag gctaatttat aaattggtgc ttagaaaacc
    51841 aaatcacttt attagctaaa gatgaatttg aagggtgaca ctttggtgtt ttatgtaaag
    51901 tttatggaag taaaacatta aataatcgtg agtatgattc ctataaatcg tatatactat
    51961 tgaaatccaa gaaaaggtat tggctaaata gctaatatct ttttaatttt ttgactccca
    52021 tatagcatta actattacat gagtatcttt aaatttatag ttaaagtatc ttaattgttt
    52081 attataaaaa tataggatgg ctaaagcaca ttaaattaaa acacttaaaa agagaagatg
    52141 tacatgagaa atataattaa ctatgataca gacttctaaa aattatttag tgaaaaggaa
    52201 cttagagtgt ataataaaag ttccttttca ataaggaaaa cgattgttat tttctgagct
    52261 tcattaccct gatattattt aaatataaac aacaacaaaa ttaacaagaa gtaaattcaa
    52321 cctaaaattt aaaatatcgg gaggtacaat atgttaatca atatgaagga aatgctaaaa
    52381 gtggcacaag aaaatcaatt tgctgtacca gcatttaata taggaagtgg gcaaatactt
    52441 aaagcagtag tacagggtgc taacgaaaaa aatgcaccag taatacttgc aatacaccca
    52501 aatgagctaa gttttctagg cgatagcttt gtagttagtt gcatagaaga agcaaataag
    52561 agtaaagtac ctatggtaat acacttagat catggggaaa ataaagaaca aatattaagg
    52621 gcaataagat gtggatttac atcagtaatg attgatggct cacatttacc atatgaagag
    52681 aatgtagcta tatctaggga aatagtagaa atagcaaaag gattaaatgt gtccgtagaa
    52741 ggagaacttg gaacaatagg aacaacagga acatcaagtg aaggtggtac tgatgaaata
    52801 atatatacag attcaaaatt agctaaggat tttgttgaaa aaacaggagt agacacacta
    52861 gctattgcaa ttggtacagc acatggtata tatccaaaag gttttaaacc agagcttaaa
    52921 ctagatttat taaaagaaat aagagaagta gtagatatac ctttagttct tcatggtggt
    52981 tcatcaaatc cagatgaaga aatagcacaa gcagttaaac taggagtttg taaaataaat
    53041 atttcgagtg atgttaagtc ggcatattat aagaagtgca gagaactatt agaacaaaac
    53101 ccaagcttat atgagccaga tactatatat ccaccatgta taaaagctgc aagagaagtt
    53161 atagagttta aaatgaatct attcaatgct atagataagt taaagtgctt ttataaaaat
    53221 aaaaattaat tatgaggtaa caaattaaaa ggaggggaga atttatgata ggtaaaatac
    53281 tacgaagcga ttgtattgta ctagataaac aattacaaac aaaaaaagat gtaattaatt
    53341 atatggcaaa tcatttgtac catggaaatt atataaataa taaagaaaag tttatagctg
    53401 atattaataa acgtgaaaaa gaatcatcaa ctaatatggg taatttaata gctatacctc
    53461 atgctaagtc aaatgtagta aatcaacctg taatgatgta tttaagaaca gatagagaga
    53521 ttacagataa tgatggtcaa aaacttaggt cattttttat gatagcagtt ccagaatcag
    53581 gttcagatga acatcttaag attatatcta aactagctac atatctaatg gaagaaaatt
    53641 ttcttaagca tctactaagt gcagaaactc catacgaaat attaagtata tttaataata
    53701 aagctgcaga atcaggagat tttagtaata atcaaaataa aggtcttata gttgggataa
    53761 caggatgtcc aacaggtata gctcatactt ttatggcaaa aaaagcatta gaggaagcag
    53821 ggcaagaact tggatatgaa gttaaaatag aaactcatgg agctataggt gtagaaaata
    53881 agttgactaa agaagatata aaaagagctg aatacgtaat aatagcttgt gataaagaag
    53941 ttcaactgag tagatttata ggaaagaaag tgctacaaaa gaaagtagta gatgctaaga
    54001 atgtttcatt agctaaaaat ttaattataa acgctgaaaa tggaatggct aaagaaatta
    54061 aaccaggtgg aaagacttta gaagattcaa aagaaatgct tcaagggtca gagacaaagg
    54121 gtgtttataa gcacttaatg agtggtgtat ctgaaatgat tccatttgta gtgataggtg
    54181 gaattggtat agccatagca tttatgtttg gtatatttgc atcagaccca actcatgaaa
    54241 catacaaccc tatagctgga ttctttggac aacttggagg cgattcagca tttaagttat
    54301 ttataccgat acttgctggt tttatagcta aatcaatagc aggaagacaa ggatttcctc
    54361 ctgctatgat agctggtttt atggcagtta ttggaggttc agggtttata ggtggtatgg
    54421 tagctggttt tgcaacagga tatatagctt taggagtaat gaagataaca gaaaatttac
    54481 cagatgtatt aaaaggagta aatgctgtat tgatatgtcc acttttgatt gcatttacga
    54541 gtggagctat aatgttcttt gtagttaata cgccagcatc atggttaaat gaagctttac
    54601 aatcttggtt acaaagtatg tctggaacta ataaagtatt attaggtgca atattagcag
    54661 ggatgatggc atcagatatg ggaggaccta ttaataaaac agcttcagct tttggattgg
    54721 ctatgttttc aagtaatata tttgagccat cagcagcatt aatggtagga ggaatggtac
    54781 ctccattagc gatatcatta gctatgttaa tattcaaaaa taagtttact aaagaagaaa
    54841 gaaagtcatc tctaccaact gctataatgg gggcatcttt cataacagaa ggcgcaatac
    54901 cgtttgcagc tgcagaccca ttaagaatga ttccagcaaa tataattggt tcttgtatag
    54961 gtggggcaat ctgtatgagt ttagatataa ctttaatggc accacatggg ggaatatttg
    55021 taataccatt tgcatgtagt gcaccagttg catatatagc ttgtatattg attggtacag
    55081 taataacagc attgattata ggggtagcaa agcctactat aagaagtgaa aacagtgaag
    55141 ttgaattact tggtgcttaa attataaata atagtaaaaa taagtaatgg aataacaaca
    55201 agtatataga ataataataa ggatatttag aatcagttaa ctacttctaa atatccttaa
    55261 tttttatttt gaaattatat tatctattat atcaatttag taaggtgtat cataaattct
    55321 tttatgatac agaagtatct tagtaatttt acatagttag taaatatgtt aaaatagtac
    55381 ttaatataaa catagaaata tataaacata ggtagggagg gctaagtatg cttgtgtcga
    55441 ggcaaattga atttcttaaa ttgatactaa acgaaaataa atatagacct ataaaatact
    55501 ttaaagataa attaaatgta tctgataaaa ctttacaaaa agatttgaag atgattgaga
    55561 aatatttaga aacttttaat ataaaaattg atataaaaag aggctatgga atattaatag
    55621 aagatttagc aaagaagaac atagacttaa ttaatagttt aaatatacaa tcgaaggaaa
    55681 ataaatcttt atcagtagag cagagaagaa tggagatttt aaagtattta ttactaaatt
    55741 caaataatat aacttcaata aatcagttag cagataaata ttatgtaagt aaaacttcta
    55801 tagtaaatga ttttaaatat atagaggcat ggataaaaga atacaattta aaacttaata
    55861 aaactttaga aggaactaag attataggta aagaagtgga tataaggaaa tcgattgcca
    55921 aaatgatgga tgatttatta gatgaaaatt atgaacaaca tgatatatct gagttaacaa
    55981 gattagattc tgctacattt agtgcattga taaatttatt tgatattgat tctattatat
    56041 ttgtagaaac tataattaca gaattagaat acaatttagg atatactata aatcagccct
    56101 actatataaa tttaattacc catatactta tatgtttaaa gagaatcgaa gaaggtaatc
    56161 aaatagaatc tcaggaagaa agagaaattt ctgtagataa tttggacgag ttagtatata
    56221 aaaatgtcac tacacttata gataaaatag aaaatagata cagagtaaaa ataacgaaag
    56281 atgaaattat gtacatatat atttttttgg tatcatctgg atttagtagc gaaaataata
    56341 gtagttataa tgatgaatca gatatattaa gtgaaagtga aaaagtttca tctataatga
    56401 tagagaatat gtcacaattt ttaaatataa atctcaaaaa tgatgactta ctacaaaaaa
    56461 gtctagcatc tcatgtaagg cctatgttaa acagattaag atatgatatc caaataaaaa
    56521 acccgttgtt aggagagata caagagcgat tttcagatgt gctgggatta tgtatgatga
    56581 ctataaatat tatgacagag tatgataatc tgaagaatat tagtatagat gaagtttcgt
    56641 atcttgccac atattttcaa gcggcaatag aaagaaatat gagtagtaaa agagtaatag
    56701 tagtttgtca tacaggatat ggaacatctc agctccttgc agccagatta aaaagagaat
    56761 ttcctgaatg gactatagtt gatatagttc ctatgcatca gttgagtaag cgaaatttag
    56821 atgatgtaga ctttgtaata tctactgtaa acttagattt gaaagataaa ttacatatag
    56881 ttgtatcagt actattaatg gaaagtgata ttaataatat aaaaaatgct ttactttcta
    56941 aacctaaaaa aagtatgaac ttagatacaa acttattagg aatgtattta gaagataata
    57001 tatattttaa ttttgatgta gctcagatgg aaagtttaat aggtgtgaat ttagggagta
    57061 aatatgaatc tatttcatta ggaaaagatt tgaatatata tatacataag caaagtaaat
    57121 taaataaagg gataatgaat atcaataatg ttactagaac gattgatatt tatttagaaa
    57181 ttagtaatca aagtttttta aagaatattt taatggaaat atcaaattta tataggcaaa
    57241 agaactatat aaactatata atagattgca agagcaaaga ggatattaaa atattattta
    57301 agaataatct attggagaaa acaaatggaa attagagaaa tattaacaga agaaagcatt
    57361 attttagatt tgaaatcaac tacaaaagaa ggcataatac aggaattagt agataaatta
    57421 tacgatacag gaagtataac tttaaaaagt aagtttataa aggcattaaa acatagagaa
    57481 aaaataggct ctactagtat aggttatcaa atggccatgc cacatggaaa aacaaaatat
    57541 gtaaagaagg catccatagt aataggtaaa tctaaaaaag gtgtagattg gccaagtata
    57601 gatggcttac ctgtaaaggt aataattatg tttgctatgc cacaatctgg aggcaatgaa
    57661 gatatgatat taatatctaa aatagcttac attttaggtg gtaaaaatat aagtgaaaga
    57721 cttttaaatg tacatacaaa aaaagaaata ttagatatat tttatgaagt gtaggtattg
    57781 tataaattat aaatttgagg tttttaaaat aaaatgtgta ttcttttaaa tagtatagat
    57841 taatttttag acactagaga ggagaggata tctatggcaa tatatttaga aatgcctaaa
    57901 ttaatacatg aatttccttt tcgtagtcta tcaaatgaag gagaagtatt aacaacacca
    57961 cactggcata aggaaataga aatattactt ataacagaag gtgtagtaaa tctatttata
    58021 aatgacaagc ctatgcaatt aaaaaaaggc gagatagtga taataaaagg aggagatatt
    58081 cattatatac tgccatcacc gggaagtgaa agattagtat ttcaatttga tatatctttt
    58141 tttaatgatt taattttatt aaatgaggaa aaagaaagct taattaattt attcagtagt
    58201 ataaaaaaat gtagtagaga ttggtcagca aaaataagaa agtcagtttt cgatatattg
    58261 atagatatct acaatgaaga cctatacaaa atagaaggat atagttatgc aataaaaggt
    58321 aaaatgtata atttaattcc tatattatat agacagattc ctagagaaat tgaagaaaat
    58381 acagtagaat atgaaataaa ctctaaagag atattagaga gattgaacaa tatattcaaa
    58441 tatgtagaaa aaaattataa acaacctata aaattagaag atgtgtctta tgaagtagga
    58501 tttagtgtat attattttac taaatttttc aaaaaaaata caggaaaaac atttataact
    58561 tttttaaatg aatatagatt agaaaaagca aagtggatat tacttaataa caatatatcc
    58621 attgtagatt tggttgaaga agttggtttt ggaagtacaa aaacttttta cagagtattt
    58681 aaagaaaaaa ttggagtctc tccattagaa tttaaaaaaa gatataatag cttggagaaa
    58741 aaagggggtg cctcaaaatg aacttagttc atgaggcact ttcttttata tgaaatcaaa
    58801 tatattttca gtatttcaac aatgaaaatt ccattcattt ataaagtcta aattttagtt
    58861 ctcaatacaa tctctatttc gaaataaatc cttttatata tataaatata cagcaatata
    58921 tgagaataag ataacaataa tgaggatata aaaatgtatt tgctatatat ataattatat
    58981 acatagatat ctaatattga tatttaatat gaaagtattg aaaatagaca atattaatta
    59041 tagtgagtaa aaaatataat tggattttta aattgaatta tttaaaaggt atagtatgaa
    59101 aaaaatctta taactaaata tgagatagaa attataaaac tttatactgt gaaagaggta
    59161 gatgcatgaa attagggaaa gattttttat ggggaggggc aatttcagcc aatcaaagtg
    59221 aaggatttta tttagatgga ggaaaaggtt tatctcagtt tgataaactc ccattaaatg
    59281 ataagagatt aaaagatgta tgtttagatg aggataatat tttaaatgaa aataatcaat
    59341 actatccaag tcatataggg attaaatttt gtgaaaatta caaagaagat atagcaatgt
    59401 tagcagaaat aggttttaaa tgttttagat tttctatatc ttggtcaaga atattcccaa
    59461 caggagaaga aagtgaacca aatgaaaagg gattacaact ttatgataat ataataaaag
    59521 aattaaaaaa atataatata gagccattaa taacgataag ccactttgat ataccttatt
    59581 ctctagttga aaaatattct gggtgggctg ataggagagt ggttaattta tatgtaaaat
    59641 atgctgaaat tttgatgaaa agatataaag atgatgtcaa atactggatt ccttttaacg
    59701 aaatgaatat gataattcat attccatata taggtgctgg gttaactttt atagctgatg
    59761 aaaatcaact tcagaaaaaa tatcaagcag cacaccatca attattagct aatgcaaaaa
    59821 ctatagaaat aggaaggtat ataaataaag aatttaagtt tgggtgtatg ttagctgctg
    59881 gaaaaacata tccatacaca tgtaaaccag aagatgtatt tgcaacttta gagcatgaaa
    59941 ggcataattt gtttttttct gatgttcaag ttaggggtgt gtatccaagc tttatgaatt
    60001 attatttaaa atcaaatcaa ataaaattaa taataaaaga ggaagattta tcaacactta
    60061 aggataatac tgtagatttt gtatctttta gctattattc tagtgcttgt agttcagcta
    60121 gagctgaagg tttagaaaaa tcaaaggcaa acggaccaga aaccataaaa aatccatatc
    60181 ttccaaaatc aaatagtgta tggcaaaacg accctgtagg gttaagaata actatgaatc
    60241 agttatatga aaggtatcag ttacctttat ttatagtaga aaatggactg ggtactcaag
    60301 atattgtaaa tgaagatgga aaaataattg atgattatcg tatagattac atgaaagaac
    60361 atattaaaaa tatgattctt ggagtaaatg aagatggaat agagcttata ggatatctta
    60421 tgtggggatg tatagatgta accagtgtaa gtgaaggaaa gatgacaaaa cgatatggca
    60481 taattcatgt tgattctgat gactatggaa gaggctcatt taaaagaact aaaaaacaaa
    60541 gtgctttttg gtataaaaaa gtaatagaaa cagatggaga aattttattt aatgatatgg
    60601 aaactcatgc ataattcatt ttaagaaagg agtgttatta tgagtttaat atttactact
    60661 aaggaccaac ttatagagca agggtttagt aaggatacaa taaaatccaa tgaaacgttg
    60721 tttacactag ctaatggaca tttaggagtt agagggaata ttgaagagtc cgattttaat
    60781 aatgagtatg tagataatat gggtacatat gtaaatggat tttatgaaga atctccaatt
    60841 acatatggag aaagcgctta tggctatgca aaacaaaatc agactatctg taagttacct
    60901 aatgctcata tagtaaattt ctctattgaa ggagattgct ttgatttatc aaaaggtatt
    60961 acaagtgaac atactaggat actagattta aatgaaggaa ttgttaaacg ttcatttata
    61021 tgggaaaact ctcgtggtag aaaagttaaa gtatctatag aaagattagt atcacaagat
    61081 atagaagaat taatgatgat ttcatataca ataacaccat tgaattttaa tggaaaaata
    61141 aaatttaaaa ataaaatgga aaatagtatg gagaagttta attgtgaaaa agtagatgac
    61201 ccaagagtgg catctataaa taagaagcaa tttaaaatta atgtaaaaaa atataacaat
    61261 aagtatttta tgaatttagt tacagaaaga agtagattag ggttatggtg tgggtttgat
    61321 tcatatatta cttgtggaaa tattacaaat gagacctata atgtttcaga tgaatgtatt
    61381 gagcgagaaa tagaagtcta tgccaaaaaa gatgaaaggt taaatttaga aattgttgta
    61441 ggctatagta gagtatattc tgatttaaat ctaaatgaag aacgtttaaa atcattagaa
    61501 tgtctggagt cgttaaaatg tttagaatca gaagcacatt taaaatcatt agaattggtt
    61561 ttaagagaag catgtaatat tggatttgat aaagtcaaaa atattcagag aaagaaaatg
    61621 aatgagtttt ggacaacctc tgatgtagag attgaaggcg ataaaactct tcaactgggt
    61681 ataaaaacca atttatttca tatttatcaa tcagcaggaa gagatggaaa gactaatata
    61741 tcagcaaaag gtcttacagg tgatggctat gaggggcatt atttctggga tacagaaatg
    61801 tatatattac cattttttat atatactcaa ccatccattg ctagagcttt attagattat
    61861 agatactcaa tcttagatgc atcaagagaa agagctaggg aacttggaat aaataaaggt
    61921 tgcttatatt catggagaac tataaatggt aatgaatgca gtgcatatta tccagcagga
    61981 acagcacagt ttcatataaa tgcagatata gcttatggta ttagaacgta ttttgaagca
    62041 actaatgatg aagaatttat gatgcaaaat ggcttagaaa ttcttataga aacagcaaga
    62101 ttttgggttg aatttggaga ttatatagaa ttaaaaaata ataaattctg tataaatgga
    62161 gtaacaggac cagatgaata tacagcaata gtaaacaata attactacac taatttaatg
    62221 gctaaatata atttaatata tgcagtacag atggtagata aatttaagca taatttattt
    62281 tcaaatgaag tatttagaaa agttaaatta caagaatatg aagtaaaaga ctggataaat
    62341 gccgctcaaa atatttattt accatatgat gaagagaaga aaataagcaa acaagacgat
    62401 tcatttttag aaaaatcagt atgggatttt aaaaatacac caaaagaaaa atatccatta
    62461 cttctcaatt atcatccatt aacaatatat agatatcaag taaataaaca agcagatact
    62521 gtactttcag cgttgctttt ccctgatgag tttagcttag aacaaaagaa gagagatttt
    62581 gaatactatg aaaaaataac tactcatgat tcatctttgt caaggtcaat atttggaatg
    62641 atggcaagtg aaattggaaa tcatgaaaaa gcttataact attttatgga cacagcatta
    62701 atggatatta ataacctaca aaaaaataca agtgatggaa tacatgctgc taatatgggt
    62761 ggaacatgga tgagtttagt atatggattt gcaggaatga aaataaaaaa ggataaatta
    62821 agttttgaac caaggatacc taaacactgg aaaaatatta aatttaatat attatttaga
    62881 gataatttag tttctgtaaa tatagaagaa tataaatctt attataagtt aatcaaaggt
    62941 aaaaacataa gcatattaca tgataataaa gaaataaaat tatcaaagaa cataatagaa
    63001 gttaataatt gttttaaagg gagtaattaa tatgaaagca gtcttatttg atcttgatgg
    63061 agttataaca gatactgcta agtatcattt tgaagcttgg catgagatag caaaatcgct
    63121 agatatagaa atagatgaaa cttttaatga aaaattaaaa ggcataagca gggaagaatc
    63181 attagataaa atattgttat ctgctaataa agtagatagt tatactaaag aggaaaagtt
    63241 aaaggtgtgt gaagaaaaaa ataacattta tataaagtta ataaactcat taacatataa
    63301 agatatatta ccagggataa atgagcttat aaaagaactt aaaaaaaata atgtgaaatt
    63361 gggaatagca tctgctagta agaatgcacc taggatatta gaatctttgg gaataaaaga
    63421 tgaatttgat tgtatagtaa atccatcctt attagaaagg ggaaaaccat atcctgatat
    63481 ttttattgaa gggagcaaga tgctaaattt aaaacaatat gattgtgtag gaatagaaga
    63541 ttcttattca ggtattaaag ctataaatgc tgccaatatg acatcaattg gtgtggggaa
    63601 aaaagaagta ctaggaaaat gtgaccatat tgtagaagat actagcttat taaattacaa
    63661 tacactatta caagcttgga gtaaaaagat taatttggat taaaattata ttaaaaatta
    63721 ttttaaaaga gaggataagg tatgaagaat aaatatgaag aagtagctca attgataatt
    63781 gatggacttg gaggaaagga taatataatt gacttaactc attgtatgac acgattaagg
    63841 ttcatcttaa aagatgaaaa gaaagtcaat gcagataaat taaaatctat agataaggta
    63901 gttggagtaa actcaacttc aactcaatat caggtcataa taggtaatga ggtaggtgtt
    63961 gtatttaatg caataataaa taaggggata aataccacag gagatattaa aagcgatata
    64021 aaaaatgaaa ataaaaaaaa tagtatttta aataatataa tagatacaat aactggttgt
    64081 atgacaccta tgataccagc ccttacagca tctgggatga taaaagttat attatctctt
    64141 tgtaccactt ttaattggct atcatcaaat tcaagtacat atagagtatt agatataata
    64201 ggagatgtag cattttactt tatgcctata atacttgcaa taaatgcagc taaaaaattt
    64261 aatgttaata catcaatagc agttatagta gtaggtgtgt ttttacatcc aaatttctct
    64321 gcatgggtat caagtgggga ccctatatca tttataggag taccaattca aggtgttata
    64381 tatgcagcat ctgttatccc tgcactttta acagtatgga tgatgtcata tatagaaaaa
    64441 ttcattaata aattaacacc tagcatgtta aaaacaattt taaatccaac tttagtatta
    64501 ttaataagtg cgccaatagc attaatagta attggaccaa taggaaattt cttaggagag
    64561 ggattagcta gtataataaa tttactacaa ggaaggttag gatttataat ggtttgttta
    64621 ttagcagctg caatgccatt tatcgttatg acagggatgc atcatgcatt gactcctata
    64681 ttcatatcag catttgcaac tacaggacaa gaatcgctaa tattaatatc tcaagtttgt
    64741 gctaatttag cgcaaggtgg cgcgacatta gctgtagcat taagaagcaa agatagtaag
    64801 atgaaacagt tagcatcagc tgcatggata tcagctatca tgggtataac tgaaccagct
    64861 ctttatggag ttacattgaa acttaaaaaa cctgctatgt tagcatctat aggagcagga
    64921 atcgcagggt tatttgcagg aattactcat gtgactttat atgttccaca aaatagtata
    64981 atggcagtac ttggattatc aggggaaaag ggaatttcaa atatagtaaa tggacttata
    65041 gttatattta tagcattggt tgctccattt attatgacat atgtttttgg agttgaaaaa
    65101 aatgttaagg aaagtacaga taatgtagta gaggaagtat aatattaact atttacatta
    65161 atagaatttt tattattatt gactataact tgttttgtat ttatattgat gcaaagaaat
    65221 aagttaatat taatgataat aattattata actgacaaaa agcaacacaa aagattgatg
    65281 aagtatatgg aaataaaaag ttgacaaaat atgtctgatg ttttatcata ttaattggaa
    65341 ttaggtagta attgtttaag tacaagctaa gcttattcat taataatagc agtatcctag
    65401 gaaggagtat gcccattatt atggataagc tttttttatg cttaaaagga ggataatcat
    65461 gataattaat aagatattaa acaataatgt tgtaatcaca ttagatgata atgatgaaga
    65521 agttatcgtt atgggtaaag gaattggtta tcaaaaatca aaaggcaatc taatagataa
    65581 aactaaagta aataaagtat ttagaatatc aaataaagaa atatcaaaca aactacaaga
    65641 attactcaat aatattccta tagaacacat gaaattatca agtgaaatta tagaatacgc
    65701 acaaataaag ttaaacaaga agctaaatga aagtatttac atatccttaa gtgaccatac
    65761 atattctgca attcaaagaa tgaaagaagg aataaatgta aaaaatgcaa ttctttggga
    65821 aattaaaaga ttttataaag aagagtttga aattggaatg aaagcactag atattattga
    65881 aaacaaaaca ggtataaaat taccagaaga tgaggctgga tttatagcct ttcatatagt
    65941 gaatgctcag ttaagtgaag gtcatacttt ggcatctgat attacgaagt taatacaaga
    66001 agtacttagc atagttaggt atcattttag gatagaattt catgaagaat cagtgtttta
    66061 ttatagattt ataatgcatt taaagttttt tgcgcaaaga ttgcttttag atagtgcaca
    66121 tgaaggtgag acagacaaag aattactaag cattattaaa tctaaatata ataaagagtt
    66181 tgaatgtgta gttaaaatta aaaatttcat taaaaaacaa tataactaca tattaacaga
    66241 tgatgagctt atatatttaa caatacattt agctaaagta gttaaagact caaatatgta
    66301 agtgaaataa tttttcagta gtatattaag aatgattgaa aggagtgata ctaacaaaat
    66361 tatacctatg gttggatggt aacattgagt tggccaaacc ttcaaatttc aaaaaattaa
    66421 tttaaacgaa atatggagga gaaaaatggg aaaatacaaa caattagcac aagagatagt
    66481 aaacaatgtt ggtggaaaag aaaatattag tggattagta cactgtatta caagattacg
    66541 ttttacttta aaagatgaaa gtatagcaaa tgacaatgta ttaaaaaaca tggaaggtat
    66601 tgttactgta atgaaaagtg gaggacaata tcaagtagtt ataggaaatc atgttgaagc
    66661 tgtctataaa gatgtagttg aaataattgg tttagatgat tcaagtacaa gttcagaaac
    66721 taaaaaatca ggtaatatac tagataaagg tatagatata atatcaggaa tttttcagcc
    66781 agtgttagga ataatggcag cttgtggtat gctgaaagga tttaatgcat tatttgtagc
    66841 aatgggatta tatagtgatg tatctggtgg ttatatggta ataaatgcag caggagatgc
    66901 attatttaca ttccttcctt tgttcttagg atatacttca gctaagaagt ttggattaaa
    66961 accaatgttg ggattagcac taggagctgc agtatgttat cctgctatac aaggtagcag
    67021 tatatcagca ggagcagatg tgatgtacac tttatttaaa ggaacaatgt ttgcatcacc
    67081 agtatatatt gatttctttg gactaccaat tgtatcaatt gattatactg gaacagtcgt
    67141 accaattata tttatagtgt attttgcttc taggtgtgaa aaattattta ataagtttgt
    67201 tccagattta gttaagtttt tctttgtgcc aatgcttaca ttattaataa cagtgcctgt
    67261 tgcacttata gttataggtc ctatcgcaac atttggttct acacttattt cacaaattgt
    67321 aatttcaata agagatttta gtccactatt ggcaggtgct atagtagggt ttacttggca
    67381 aattcttgtt atttttggta tgcactgggg atttattcct gtatatataa acaatgttat
    67441 gactttagga tatgataatg ttatgatgcc attctttgct tgtacatttg caagttcggc
    67501 agttgtgttg gcaatatttt tcaagactaa agataaaaaa ctaaaagaga tgacaatacc
    67561 aaactttata tctggtatat ttggagttac agagccagca atttatggaa tattattgcc
    67621 tttaaagaaa ccatttataa taagttgtat tgctagtggg attggaggcg ctttctacgg
    67681 attctttaat cttagaaaat ttataactgg aggtatggga atatttgaac ttccagcaat
    67741 gattgaacca gatgggggaa tgggcaactt aatagtagct ctttctggta tagctatatc
    67801 aatggtcgta gcttttgtat taactatgat tttatataaa gatgagaaag tagaagagtc
    67861 taaaaaagta agaaataagg ggaaagaaga aataaaagaa gtcaagtcta ctaaattaga
    67921 aagagaaata gtagcaagtc ctataaaagg tgaagtatta aaattaagtg atatagagga
    67981 tgcagcattt gcatctggtg tactaggtca aggggtggca ataataccta gtgatggaaa
    68041 agtagttgct ccagtagatg gtgtagttac aaccttattt cctagtctac atgctatagg
    68101 gattctttct gatacaggtg ttgaagtgct tattcatatt ggattaaata ctattcaatt
    68161 agaagggaga ggttttgagg catgtataaa acaaggtgat agaattacaa aaggtcaaac
    68221 tatattaaac tttgatgttg atgcaataaa agagttgggg tatagtactg taactccaat
    68281 tgttattaca aattcatcac aatttttaga tgtagtagaa acagaaagta aaaatattga
    68341 attagaagat aatctaatta cagtcttatt ttagtaaaaa ttgaggcatt agcataagct
    68401 agtgctttgg ttataattta aggaggcttt gactatgagt tttaaggatg attttttatg
    68461 gggaggagct actgcagcca atcaatgtga aggtggatac aatgaagacg aaagaggatt
    68521 ggcaaatgta gatgtatgtc caacaggaaa agatagaaca gcagttatta cagggaaact
    68581 aaaaatgttt gattttgatg atgagcatta ttatccagct aaaactggta ttgatatgta
    68641 tcataattat aaagaagata taaagttatt tgctgaaatg ggatttaaag tatatagaat
    68701 gagcattgca tggagtcgaa tatttccaaa aggtgatgaa gaaacaccaa atgaaaaggg
    68761 acttcaattt tatgaaaata tatttaagga gtgtaaaaaa tataaaatag agcctttagt
    68821 cactattaca cactttgatt gtccaatgca tttagttaaa aagtatggtg catggcgtaa
    68881 tcgaaaaatg ataggtttct atgagaaatt atgcaatgtt atctttagaa gatatagagg
    68941 attagtgaag tactggctaa cctttaatga aataaatatg attttacatg ctccatttat
    69001 gggtgctggt atttgctttg aagaaggtga agatgttgaa aagataaaat atcaagctgc
    69061 tcatcatgag cttgtagcta gtgcaattgc aactaaaata gcacatgaag ttgattcaaa
    69121 taacttagtt ggatgtatgt ttgcagctgg aagtgtatat ccttatagtt gtaatcctaa
    69181 tgatgtatgg gaagctacaa agttagatag agaaaattac ttctttgtgg atgtacaatc
    69241 taaaggtaaa tatcctaact atgcgttaaa gtatatggag caaaaaggta ttacaccaga
    69301 aatggaacct ggtgatattg aattattgaa taaatataca gtagatttta tttcattttc
    69361 atattacaat agccgttgtg ttagaactga tgaaaatgca gatgatatgg ctgaaggaaa
    69421 catatttaca tctgctaaaa atccatatct ttcatacagt caatggggat ggccaattga
    69481 cccattaggt ttgagaatta cactaaatca tgtatatgat agatatgaaa agccactatt
    69541 tattgtagaa aatggattag gtgctaaaga tatagctgat gaaaatggtt atgtagaaga
    69601 tgattacaga attaattatc taagagaaca tataaaagct atgcatgatg cagtttctat
    69661 agatggggtc gatttattag gttatactac atgggcacct attgatttag taagtgctgg
    69721 tacaggtgaa atggaaaagc gttatggatt tatatatgta gatagagata atagtggtaa
    69781 tggaagtcta agaagaatga aaaagaaaag ttttgaatgg tataagaaag taattgcttc
    69841 aaatggtgaa gatttatatt aaacaagaaa tctatgttaa ataagaaatt tgtattaaat
    69901 aagaagagta taaaaattaa taataagtat aatttttaac ttttttaact atagaaaatc
    69961 aatacagaat tattttacat tgtatttatg caatagtatg attcacaaat aaaattttag
    70021 aaaataaaat tgttaagaag tatgggaagt aagtgcaatt tactttgtaa taaaagatga
    70081 aaaaggcgag cttaggtttt aagcttgtct tttttattat gtataaacta tgatacttta
    70141 aaattctatg aaaaatttat ttaatagaga aattaaaaat ttaatggtaa tcaaattctt
    70201 taccaatgaa tataaaaaat gtctacgtgt tataatagtt taaactaata aacgaaaggt
    70261 agatgaatga atatgaaata ccaacatata atagaagttg acaaagaact ttgcattgga
    70321 tgtgggcttt gtaaaaatga ttgtccagta aacaatataa ttatagaaaa taaaaagtca
    70381 gtaattaaaa aacaagattg tctaatgtgt ggacattgtg cagcaatatg tcccacaaaa
    70441 gctattacct tgacaggatt tgatgaacct cctatagaac ttacaaataa gccaaagcta
    70501 gattcagatg aattactaat ggcaattaaa tctagaagaa gtatacgtaa atttaaagac
    70561 aaagaagttt cttcagaaat tgtaaagcaa attattgagg caggtaggta tacccctagt
    70621 gctaaaaatt cacaagatgt atcatatatt gttttagaca ataaaaagtc aatttatgaa
    70681 aacgaagcag tgaaattttt tagaaaaata aaacctattg caaatatagc tattaaatat
    70741 tcaaaagaag ttgagattga cgataacttt ttctttaagc atgctcctat tgcaataatg
    70801 ataattacaa aagataagat tagtggttca cttgcagcat caaatatggc attaatggca
    70861 gagtcttatg gtctaggtgt tttatttagt ggatattttt cagatgtagc aaataattcg
    70921 ccaaaattaa aaaagctttt aggtctaaaa cgcagtaatc atgttcttac aacattagta
    70981 attggatacc cagatgttaa atatagacgt actgcacaga aagaagtagc aactgttaga
    71041 tacttataag agagggtgga ttttatggaa aaagaatgtc aacaaagaat gcaagaaata
    71101 acatctaaat ttaaagaatg tcgcaaagct atctctgcta tgggtgatga gactagacaa
    71161 ttgattttaa ttgctctctt agagagtgat tttaatggta tacgagtggg agaaatcaca
    71221 aaaaaaacac atctttctcg tcctgctgta tctcatcatc ttaagatatt aaaagaagca
    71281 gagattgtta atttgcgtag agaaggaacg aaaaattatt attatcttga ttcaaaaaaa
    71341 tcacaatgga agtcactaac agagctaata aatcttatat ttgttggaat acaacatatt
    71401 agtgaaaatg atataagaaa aggtgattaa attatacttg atttaataca aaaagattga
    71461 tttaggaact aaaaagttca ctttgagaca ctatcttttg aactataccc atcttaggag
    71521 acagttaaaa tatgtaaaac tgtataaaac aatgggtata gttcatttta taatggttta
    71581 aatattaaga atatattatt ctaaatagta tctttctctg ttttgagttt tatttttata
    71641 ctcaatagct tcagtggggc aaccacaaat acatgccata caatgagtac agctattttt
    71701 ccaaactggc tttttgtttt ttaaattaat attatttaaa ggacatagct ctacacattt
    71761 tccacagcca atgcatttat cagtataatg aaatcctttg gcactaataa ttgtcttata
    71821 aaaaactgta tttattatac cacttttaat tgtacctcct aagccactag gagtaatagt
    71881 ttcaaattca ttttcattgc gtatatcaga aataatccta tatatttgtt tatctgcttc
    71941 tttaatcatt tgttttgatg tttctttgtc tgttgtagaa aataaagcta tataattctc
    72001 tggcatttta atttctgcca taccttttaa ttgccattcc ttgtatttac atagtttttg
    72061 aatatagttt atggattttg ctgtatctcc cccacaagtc attacaaagt aaactctgtt
    72121 gtctcctaga aattttgttt cttttataaa atctgtaacc actattggca atctccatgc
    72181 ataagtagga catacgaata tgaatggttt acctgctgat attaattcat ctgttttttc
    72241 ctcttttata agttgattta gtgatatcag ttcatcattt aattcttgtg caattttacg
    72301 agccacatat cggctattac cagtaccgct aaaatataaa atcataataa tatctcccta
    72361 actatttttt attttaactc ttaatttttt atttattata gtactttatt gaaatattct
    72421 attcaaatgt atgtaaaatt tagtagttaa gaaaattata acacattagt aatttttata
    72481 ttcattggta aagaatttga ttaccattaa atttagtaac aaaatatcaa ctggattttt
    72541 atataagaag agatagtaat tttcatgtga aagattgtaa atataaagat gattttgaag
    72601 ggcaataaga agataaaatt gatagcttaa taaaaaatat ttaactttta tattaactgt
    72661 tttaaatatt ataattatct atcttgaata atcaaccata gaagactgta tacaaagaca
    72721 aagttgtgta cagtcttttt tataaattta atgtctataa ttaaatacac tattaaaatc
    72781 aataagttat tatttcaaag tagtattatc caaattttta tgatggttaa tacaatttgt
    72841 tagccatttt atagcacctt gttccctgat aatagctcca tcaagaacta tataatcacc
    72901 aaaatcatta ctatcaagag gaggaacttc actataacgc tccatttgac tgtacaagaa
    72961 cgtaattctt tcttggtgtt gaagcaattg atgctctagt aaaataagcc tagtatctat
    73021 atctaaatta ttagaaaaat acattctaag acgaaaaata tccttagggg ttctttccat
    73081 tggctcatcc ttttcaagcc atttcaagaa ctcatcttta cctttttctg tgattgtgta
    73141 taactttttc tctaatacat caccactaat tttaatatca tatacaataa gcttttcatt
    73201 taccaatttt tttagttcag gatatatttg actatgcttt gcattccaaa actcagctaa
    73261 ttgaaaattg aactccttta cgatatcata accagtcata ggatttctat ttaataatcc
    73321 taaaattgca tactttaaag ttcgcataaa tacacctctt tctttaatta catacttatt
    73381 ataacacgat atatttagtt tgaattaatt aatatagcta tgttttaata agaactttta
    73441 aattatgagg aacaaaaaat aaataaaact atatataaaa atgaaattat gtaaatataa
    73501 acatgtaagt atttacatgt ttatatttac atatagaaaa aattgtgata atcttaacta
    73561 agaaattcta tttaataaat ttatcgagga ggagagtaat gaatttaaca caaaaaagat
    73621 ggattatatt aattgcaagt tgtttcatca atttatgtat tggttcaata tatgcgtgga
    73681 gtgtatttgc atcacctatg gcagaacatt taaatagtct tgctggaaca acttttacag
    73741 ctgctagttt agcaattgta tttacagtta caaactcagt tggacctatt actatgatta
    73801 cagggggaat gataaatgat aaatttggtc ctaaaaaagt tgtatttgta ggaggattaa
    73861 tttttggtat aggtatgata ttggcaggtt tctcaaaagg attgcctatg ttgattttat
    73921 catatgggat aataacaggt cttggggttg gcatggttta tggatgtaca ataagtaatt
    73981 caattaaatt ttttccagat aaaagtggat tagttggtgg tataacaaca gcagcttatg
    74041 ggtttagttc agtaataatg cctccagttg ctaattggat aattaataaa tatggagtaa
    74101 cttctgcatt taaatcaata ggtttagtat ttcttataat tgtatgtgtt tcttctttct
    74161 ttatcaaaaa atgtccagca gatttcacac cagaaggatg ggtaccacca gagaaaaaag
    74221 gaaaagtaag agttgttatt aataaaaatt ggaaagaaat gctttcaaca cctatatttt
    74281 atctaatgat tataatatta acttgtggag ctttctatgg attaatgtgt gtgtcattag
    74341 catcttctct agcaacaaat atgattggga tgacaagttc agattcagca atagtggttt
    74401 caattttagc cttgtttaat acattaggcc gtattgttgc aggatatata tcagataaaa
    74461 ttggtagaat aaatacttta tcaggtgcat tagttatttc aatttttggt ttattatgtt
    74521 tgttattctc aagagaagga gatgtagcaa cattctatat tggaataata attataggta
    74581 tatgttttgg ttcatttatg ggaattttcc caggatttac agtagataaa tttggaccta
    74641 aaaataatag tgtaaattat ggaatcatgt ttattggttt tgcttttgca ggatatattg
    74701 gacctgcagt gatgaaaaat gtatattctg tagatggcaa ttatcaaagg gctttcatta
    74761 tagctataat tatagcttta ataggtttta tattaacatt tttatataaa tatataaata
    74821 aaatacaaaa tttaaagata gaaaatttaa taaagggaga tataaaaaat ggaaagaaaa
    74881 tatccaaatc tatgtaagcc aattaaaatt ggaaatgtaa cattcaaaaa cagaatgttt
    74941 tcagcaccta tggggggaac agacataaca gcagattgta caattggctc aaaatcaaca
    75001 gccttttacg aattaagagc aaaaggtgga gcaggtgcag ttacaattag tgaatgtatg
    75061 gttcatccag aaacagatgg ttcacatgca tatcatctag acttaaaaat agttgattcc
    75121 ttagcaagtt ttacttatac agcagatgca attcgccgtc atggagcaat accaagtgta
    75181 gaactatctc attcaggaca atattcagga acttatttag ttgacaaaga taagaagcga
    75241 ggattatcac aatggggagt aagtcctagt gttcgtcctg atggattaga gataaaagaa
    75301 cttacagaag aaataattgc tgaaatagta gagtcatatg gaaatgttgc agcattggct
    75361 aagagagcag ggtttgagat gattatgatt catggtggac atggctggct aatcaatcaa
    75421 ttcttatcac cttactttaa taaaagaact gacaaatatg gtggttcttt agaaaacaga
    75481 gttcgttttg ctaaagaagt tttagatagt gttcgtaaag cagtaggtcc aggatttcca
    75541 atagagttta ggatgagtgg ttctgaatta tttgagggag ggtatgattt agattatgga
    75601 acagaaattg ctaaattatt ggaatcaaga gtagatttac ttcatgtatc agcaggtaca
    75661 taccaaagag ggtttgcagt aacacatcct tctatgttct tagaacatgg atgtaacgta
    75721 tatcttgcag aagaaattaa aaaacatgta aatattccag ttgctactat aggagcatta
    75781 aatgacccag aaatgatgga agagataatt gctagtggaa aagcagatgt tatttacatg
    75841 gctcgtgcat tactagctga ccacgaatta ccaagaaaag ttatgagtaa tcaagatgaa
    75901 aaaatagtga aatgcctaag atgcttcact tgtatggcag aacgtgctac cacttctaca
    75961 agacgctgca ctgttaatcc acttattgga cgtgaattag atggaactga agttgtttca
    76021 gtattaaaac ctaaaaaagt attaatagca ggtggtggac caggaggatt gcaagcagcc
    76081 attacagctg taaagcgtgg acataaagta atactttgtg aaaaaactaa tgaattaggt
    76141 ggaattttaa agggagaaca agcacttcca tttaagtata aaatgtatga attaggaaat
    76201 acttttggaa aaatagcaaa agatttaggt gttgaagtac gtttaaatac aacagttaca
    76261 aaagaatatg ttgaaaatga aaatgtcgat gcattaatta tagcagtagg gtctgaacct
    76321 cttgttccac caatagaggg tcttgatgga gaaaatgtag taatagttaa tgattattac
    76381 gtagaaaaag aaaaagtcac tgacgaagta atagttttag gtggaggatt agcaggatgt
    76441 gaggctgcaa ttcacttagc tcaagaagag aagactgttc acttagtaga gatgagagca
    76501 gaacttgccc cagatgcaaa tataaggcat cgtccaatat tattagaaga aatagaaaga
    76561 caaggtatat atgtatatac agaacataag ggtttaagtg taacaacaga aggtgtagta
    76621 tgtatgaata aatctgggaa taaaataaat attccaggaa cctcagtaat atgtgcactt
    76681 ggacaaaaac caagaagaga agtggtagac actttacttg attctgctcc atatgttgct
    76741 caaattggag actgtgttcg tgcatctaca ataacaaatg cagtatacca agggcatcat
    76801 gctgcgctag atatatagtt aaaaagacgt agatagtatt gttttattat aaaaaaggag
    76861 tgtctcaaaa tgaacttttt agttcatgag acactttttt acatgaaatt aaatatattt
    76921 ttatcatttc aacaatgaaa aaagattatc tttattttga gacagcactt ttgttattat
    76981 gattttaatt cttattgcaa gttttcattt gattgatgag taaaactttt taagatgtag
    77041 aagtatttaa caatgtaaat gaccctaact taaatacttt agcgaaggtt gacagatttg
    77101 tgtttgcttt tatctattat aacttaagga aacatgttac ctgaacaata aatttatata
    77161 ataaaagtat ataaatatat atatgaatgt taagattagt tgatagaatt taaataataa
    77221 atccaatatt ataaacatag gaggtatgaa aaatatgatt aatgagaatt taaaaagtct
    77281 aagaaaaatc caccagtata cacaagaaga attagctgaa aaacttaatg tttctagaca
    77341 atcaatagca aaatgggaaa gtggagtttc ccaaacaaaa ggatattact gaaataacct
    77401 gtgtttacct gcttgtagag aaaagaatat tgctattaag ccagagatac tacataaatg
    77461 tgttggtatc tctttttcgt taatgcaaca cagtaaatta tttcattttc ctaattattt
    77521 tagactgata agtaactttt taaatgaaga aaagaaatga caatacttaa aggagcatgg
    77581 tatacttaaa ggagaatttc attaaggagg aaaaagagat tgtttaatct aatagaaatg
    77641 ttatttccta taatgtttat actgattttt ataataattg ttttcacttt tgtgaaagga
    77701 atagctactt ggtttaaaaa caataattct cctcgcttaa ctgtgtcagc aagaatagta
    77761 gcaaaacgtc agaataccac tcataacaat caaccaaacg ctggtgatat atcaggagca
    77821 catggatttc atacaatttc cagcacctcg tattatgtga catttcaagt agatagtggt
    77881 gatagaatag agctgtctgt atctggctca gagtatggag tgcttgcaga gggagataaa
    77941 ggacagctga cattccaagg cacaagatat ttaacatttg atagggaaaa ttgaatttag
    78001 aggtgcatta tgaataagtt tttgagtcag ataaggcgta tagataatga aatatctatt
    78061 actaggaaaa ttataaatac aatatttata ctgtgttttg gaatagtttt aggaactttt
    78121 gcaaaatttt tagatactac agcaagcaat actttaccat ttatatttga atatttagat
    78181 attagtaatt tttttggtcg ttttgctata tggttattga ttgctttgta cattgcaatt
    78241 tatagtcatt cttccataag agcatcatta aatgtgttag tatttttcat tggaatggtt
    78301 tcaagttatt acctatattc gtattttgtt gctggatttt ttccaaaaaa ttatgcaatg
    78361 atttggcttg gttttactgt catttctcca ttgttagctt ttatttgttg gtatgctaag
    78421 gggaaaagca aaatatcttt tatactttca gtaataataa ttgcaatttt atttaatttt
    78481 acatttattt atggttggat ttattttgat gtgtattcaa ttttagaagt gatagtcttt
    78541 ggttgtgcat taatagcttt aaaacgtaac acctttaggg agacaacgta tatgatattg
    78601 agtgcagttg ttattgctgt tatacttaat atgttagttc catttcattt tggttaggca
    78661 gattttaaga ttattataga tagaatataa atttcacgaa ccgccgaagc gatccgccag
    78721 cggtggcggt cgtaagacat atcgccacgc cagcttgctg gcgaggtggc ggttcacttt
    78781 ggcggtttgg cgagcctgcg agctttctaa gcccccgtta tctaacaggg ggggactatt
    78841 acaaaagaca agagcaaaaa caaatataaa actgctgata tgcaacgatt tataaggttg
    78901 taagaactta tttcacttta caccctattc tttctacccg acaggtctaa aacagcatat
    78961 caatagaaaa taaatataag atacaaggtg tatgctccta tgagtatatg cctttttttg
    79021 attggaggaa tgaagcatga atgatatgaa atttattgaa acattaaagc aaaagagaaa
    79081 tgtctgtgat tattcgcaat cacgactggc acaggaacta caaatcaaca ggcagaactt
    79141 aaatgaaatt gaaaacggaa aaacaaaagc cagtaaagaa atgaaacata tactcttaca
    79201 ttatcttgat tattgtaatt gtacacagcc tttcacttta acgattgact atctgcgtgt
    79261 tcgttttcct accacagacg cattggaaat tataaaaaat gtgctggcaa tgaaaagcga
    79321 atattttata catgaagatt acggaatgta tgcttatgaa gaacagtata tctatgggga
    79381 tattagtgta aatgcttcta aagatagttc tatgggtgtt ttattggaat taagaggtat
    79441 ggggtgtcgg gacttagaat atgttttaca ggtaagaggg atagactggt attgcttttt
    79501 aagatgttgt atagattatc aaggtgtttt taaacgcata gatttagcag tcaatgatat
    79561 gggcggattg ctggatatag aaattctaag ggaacgttat tatgctaaca aggtatggaa
    79621 acgttcaaga acccatgaag cagtagacag cggaaaatta tcgggtacac atggagatac
    79681 tgcaaaaact ttttatatcg gttcaaagaa tagttctatc tacttttgct tgtatgaaaa
    79741 agaaaaggaa caaaaaagca agggtataaa aacagatatt aagaaccgct tcgaaattcg
    79801 tttaaaaaat ggaaaagcag gacaaacggt agagcaactt gttttttcaa gaaatcccga
    79861 acagaccata gcaagcttta ttctcacaca gatagatttt cccgattata ttttatggga
    79921 tatattttta gataatgtaa cgacctcact tccgtttatt atgacacctg ttgctgttaa
    79981 tatggataaa ataaaacgct ggctagaaag acaggtcatg ccctctttat tgatgataaa
    80041 agagattgaa aagaaaacag gagcaaatta tctggaagaa atcgacaggc atacaaggct
    80101 aacagaaaag cagtaattaa agattaaaca aatgacaaca gacatagcag atatgattga
    80161 gaaagatacc gctgttccac aagggaatga cggtattttt taatttcttc aaaaaaactg
    80221 caacaaaatg actgcttgtg tacagatatg gtgcgaggaa aggaaatcta actttttttg
    80281 aaaacaggtc attaaatcgg tggctgctgt ccctatatga tgtgaaagaa gaaacgattt
    80341 ttaatttcaa cttaacattt gacagttttc attccctata tggagcaaag aaaatctttt
    80401 attccatagt tggcagttac ggtgttgcat gggtagttag ggtgtgaaaa gaaaaacaga
    80461 tttttttcat caccaactta gcaaactgat acttgctttc cctatatggt gcaggaaaag
    80521 agagtttaac tattttcatt tcaacttagc aactggacgt ttgctgtaca gatatgtagt
    80581 gaaaagagaa aaagttttga atattggtta cgcttcggct cttttccaac gcggtatata
    80641 ggaaagacga ttttcttctt tcatgttctt tgacaactga ataaagcaat tcaatacgtt
    80701 tgacagacag cgatccattg aagcagatac gccatgacct tttccctgca aaagcgagcg
    80761 aaccctattt gtgttcctgt aaaagacttg tcctctttta tcgccatgac ctgttctgtc
    80821 tgataaatga tactcccgta cagccacagc ttgaacgttc agagcgtcgc acgcaatggg
    80881 tacggctaca taagaactat gcagaggtgg aattcctgtg ggctatgaca aatgccgttg
    80941 aattgcttag aaaaaagatt atggaaaggg ggtatgtgtt attgctgata ttgtaaaaac
    81001 aatgcaagaa aagacaaata ataagcgtag cattggcaac agaggaaaaa caaagattgt
    81061 tgtaaaagag catttttccg aaaagggaaa gacaatggag gaacttctga ctgatgttat
    81121 gctggaaaaa gcaaagcaga caatcgcata aaattggtgc agttgtaaga catagattga
    81181 atggcaaaaa gtacccgtgt tatactttac ttgcaagcag gtattgtaaa cacgggttag
    81241 ttataaagga ggataactga caatgaaaca acagatttac aatactgcac tttatcttag
    81301 gttaagccga gatgatgaat tacagggcga aagttccagc attaccacac aaagaagtat
    81361 gttgcgtcta tatgcaaaag aacatcattt gaatgtgatt gatgaatata ttgatgacgg
    81421 ctggtcggga acaaattttg aaagaccgag ttttcaaaga atgattgagg atatagaggc
    81481 aggaaaaatc aactgtgttg taacgaaaga cctttcccga cttggcagga actatattat
    81541 gacaggacaa tatacagaat tgtattttcc cagccataat gtccgttaca tagcgattga
    81601 cgacggtgta gacagcgaga aaggcgaaag tgagattgca ccatttaaga acatcatcaa
    81661 tgaatgggtg gcaagagata caagccgtaa agtgaaatcg gcatttaaga cgaaatttgc
    81721 agagggtgct cattatggtg cttatgctcc attaggatat aagaaacacc ctgacatcaa
    81781 aggaaaactg ctggttgatg atgaaacaaa atggattgtt gaaaaaatct tttccctagc
    81841 ctatcaaggt tatggtagtg ccaaaatcac aaaggtactg cgagaggaaa aagttccgac
    81901 agcgtcttgg ctgaatttta caaggtacgg tacttttgca catatctttg agggaaagcc
    81961 cgaaagcaaa cgttatgagt ggacgattgc tcatgtcaag gcaatcttaa aaagtgaggt
    82021 ttatataggc aacagcgttc acaatatgca gtctacggtt tcattcaaga gcaagaagaa
    82081 agtgcgtaag cccgaaagtg aatggtttcg agtggaaaat acccatgaac cgattattga
    82141 caaagaagtg ttctatcgtg tgcaggaaca gataaaatca agacgtagac agacaaagga
    82201 aaaagcaaca ccgatatttg cagggcttgt caagtgtgcg gattgtggct ggtctatgcg
    82261 gtttgcaacg aatacggcaa ataaaacgcc ttacagttat tatgcttgca gttactacgg
    82321 gcagtttggc aaaggtactt gttctatgca ctatatccgt tatgatgtgt tgtatcaagc
    82381 cgtattgaaa cgattgcagt attgggctaa ggcagtacag caggacgaag aaaaggtgct
    82441 gaacaagata cagaaagcag gcaatgcaga gcgaatacgg gaaaagaaga aaaaggcaag
    82501 tgcctttaag aaagccgaga accgacaaaa tgaaattgac cgtttgtttg cgaaaatgta
    82561 tgaagataga gcctgtgaga agataacaga gcgaaatttt gtgatgttgt ctagcaagta
    82621 ccaaaaagaa caaatagaac tggaacagca gataaccaac ctaagagaag aattaagtaa
    82681 aatggaacag gatatgatag gtgctgaaaa gtggattgag ttaatcaagg agtattccgt
    82741 accaaaggaa ctgacagcac cgttattaaa tgcaatgata gaaaaaatcc ttattcatga
    82801 agcaataacg aatgaggata acgaaagaat acaggaaata gagatatatt accgatttat
    82861 tggaaaagta gactgataaa gagggttcat atctttaact aagggaaact ggagaatcta
    82921 ttcctgatat aggtagttgc attaaacttg caaaattgta caaggtcaaa ctagatgact
    82981 tagttaatca ttcggaagaa aaaacaggta ttatagtacc tcctaaagga aagtttttct
    83041 ttggagcagt agtagttggt gaacgtggtc agattgtcat tccaaaagaa gcaagagaag
    83101 tatttaatat aaatgcagga gataaattat tggtacttgg agatgaggaa agaggattag
    83161 gaattgttca tcaacgtgat ttgataaatt ttataggtca tatgggagta gtacgtaaag
    83221 aagaatgatt ttaaaaaatt ataaaaggag gtatgaaatg tgagtaaaat agtatttttt
    83281 agcattcttg catatggtca tactaatcct actattgaag tagttcgtga attagtggat
    83341 agaggaaatg aggtattgta ttattctttt aatgaattta aagataaaat tgaaggtgct
    83401 ggagcaaaat ttatttgttg tgataaatac cttccagaat tactccctgg agatgagaaa
    83461 aaaattggta aggattttcc tggattaatt gagatgatag tagatactac tatttcttta
    83521 gatgaaaaag tttgtaggga acttaaagat tttaatccag attgcattgt atcagattca
    83581 ttaagttttt ggggaaagtt atttgcacaa aaacttaata ttccatatgt atgctctaca
    83641 acaacttttg catttaataa acatacagca aagttgatga aacaaaactt tatagaaatt
    83701 atacgtatga tttttggtgt aagacgcatt aataaaaaaa taaagctttt acaaagaaaa
    83761 gggtatgaag taaaaaattt tatttctata gtttctaatg ataatgatac ggataccatt
    83821 gtatatacat caaaagaatt tcaaccaatg gtagaaacct tctctagtaa gtattcattt
    83881 gtaggtccat cagtatcaaa gttgattatt aaacctaaag agagaaaaag aaagttaata
    83941 tatatttcgc ttggtacaat taataataaa aatgttagct tttataaaaa ctgtataaat
    84001 gcatttaaag attctgatgt tgatgtgatt atgtctgttg gtagaagtac tgatattaaa
    84061 agtttaggaa atataccaaa taattttgag gttaaaaata gtgttgaaca gattgctata
    84121 cttcaaaaaa ctgatgtgtt tattactcat tctgggatga atagtgttaa tgaaagttta
    84181 tattatggag tacccatggt attatttcct caacattcgg agcagagaat ggtagctaag
    84241 agagttgttc atttgggagc aggaattatg ttaaaagagg ataagtccga aagtattaaa
    84301 aaagcagtat ttcaagttat aaatgacaat gaatataaag aaaatgcaac taaactatca
    84361 aaaagctttt ataatgcagg aggctcaaaa aaagcagcag atgtaatatt acagattata
    84421 tgtaatagta gacaagttga catataatag atttgttaaa aatatatata catacatgca
    84481 atttaatcaa agtactgaca gtggggtctt ttaacctacc agttggggca tatatattga
    84541 tgctaaatat gagggatgtt atattttaat aaaaaagata acatcctttt tttagtgcgt
    84601 tatatcaagt tttaaataat aaatgaagga ggattaatat gaaaaaatat aaagttattt
    84661 ttatagtatt aattataggt attataagtg taacagggtt tgttgtatat aaaaactgca
    84721 ttaaaccatg gaaagatgct gaaacatata ttgataagta tatggtaaaa caagatattt
    84781 caaaagataa tataaaaagt attacaaaag aaaaagccaa gaaggcaagt tacgaaggaa
    84841 tactatacaa agtgtattac aaagatgacc ctcgatatga gtatcaatat ttttatagtg
    84901 ataattatca tgctctatat gtaaataaag taatgttaca aatttatgat gtggaaaata
    84961 ataataaact tttaagaagt aatgaggaat taaaaagtgt aaagtatcca ccaatatatc
    85021 ttaaatataa gccagataaa tgatttatga caaaatagaa tgatttttat taaaatttat
    85081 ttaaaaatat cactagagtg tttaaataaa actaaattta agtatttata tattagtata
    85141 tcttactagt gtttaaacaa aattaaattt aag
//
LOCUS       DAMJYN010000005        81167 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.005, whole genome shotgun sequence.
ACCESSION   DAMJYN010000005 DAMJYN010000000
VERSION     DAMJYN010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 81167)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 81167)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..81167
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.005"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            86..1144
                     /locus_tag="PC466_000412"
     CDS             86..1144
                     /locus_tag="PC466_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5009 domain-containing protein"
                     /protein_id="HDF2767842.1"
                     /translation="MIVCNNPGTWMRMYPQLRHAVWHGVTLADFAFPFFVISLGVTIP
                     ISINSKLKNNKSTLSIILSIFKRSILLILFGFFLNYLGNPDLNSVRILGVLQRMGLVY
                     FVTSLVYLLLKKLNVGSTATIITFLCIATFIIVGYYILAKPYGFELEGSLAQLVDLHF
                     FKGHLYKPEFEPDGFLTSIVAISSGMLGCTMGCVLLKENIGEYKKFFKILVMSIILLI
                     GAFIFNQYFPFNKRLWSSSFVLLMAGSYGMLLSIFYFICDIKNKSKIFTPIIALGSSP
                     IFTYMCLEILSHVFWNVPKLTNKVDYPTTLVEWTTYELITPWAGTTWDSLIFSLLYVL
                     FWVIVMSIMYKKKIFIKI"
     gene            1398..3422
                     /locus_tag="PC466_000413"
     CDS             1398..3422
                     /locus_tag="PC466_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDF2767843.1"
                     /translation="MKKTTKLLATGMLSVAMVAPNVALAAENTTANTESNSDININLQ
                     RKSVVLGSKSNASVKFKEKLNADSITLNFMCYDMPLEATLNYNEKTDSYEGVINYNKD
                     PEYLNVWELQSIKINGKDEQKVLNKEDLESMGLNLKDYDVTQEFIISDANSTKAVNEY
                     MRKTSAPVKKLAGATRFETAVEISKQGWKDGSSKVVIVNGELAADGITATPLASTYDA
                     PILLANKDDIPESTKAELKRLNPSDVIIIGDDGSVSQKAVSQIKSAVNVNVTRIGGVD
                     RHETSLLIAKEIDKYHDVNKIYIANGYAGEYDALNISSKAGEDQQPIILANKDSVPQG
                     TYNWLSSQGLEEAYYIGGSQSLSSKIIDQISKIAKNGTSKNRVSGADRHETNANVIKT
                     FYPDKELSAMLVAKSDIIVDSITAGPLAAKLKAPILITPKTYVSAYHSTNLSEKTAGT
                     VYQIGDGMKDSVINSIASSLSKHNAPTEPDNSGSAAGKTVVIDPGHGGSDSGATSGLN
                     GGAQEKKYTLNTALATTEYLRSKGINVVMTRDTDKTMALGERTALSNTIKPDLFTSIH
                     YNASNGAGNGVEIYYKVKDKNGGTTKTAASNILKRILEKFNMKNRGIKTRTLDNGKDY
                     LYVLRNNNYPAILVECAFIDNKSDMDKLNTAEKVKTMGTQIGIGIEDTVK"
     gene            3642..4328
                     /locus_tag="PC466_000414"
     CDS             3642..4328
                     /locus_tag="PC466_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HDF2767844.1"
                     /translation="MSGYTNDECEIPKIKSYPGADKEIASEIDYSIVKGTVLFDLYQR
                     IMDLVLSIIGLVIGLPLIAIFGILIKIEDKGPITYKQERLGKCGRRFYIYKLRSMRTD
                     AEKFGAQWAEKDDPRITKVGKFIRKTRIDEIPQLFNILKGDMGLIGPRPERPNFTVQF
                     NEEIPGFINRLAIKPGLTGWAQVNGGYEITPEEKLKEDIYYIKNRSILLDFKILFKTV
                     KVVLTGDGAR"
     gene            4423..5478
                     /locus_tag="PC466_000415"
     CDS             4423..5478
                     /locus_tag="PC466_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp7"
                     /protein_id="HDF2767845.1"
                     /translation="MIKKISTILSLVLLISISSTIEVFADANPKRELIEGSIPEISTE
                     LNKRAFKDSKEVILVNEESIVDSISATPLAYAKNAPIVVTKSKNLGRVTRNYLKELGP
                     EKVTIVGGLKAVSKDAERNIEKMGIKVERIRGKDRYDTSLKIAREMYRTVGFDEAFLL
                     SSTTGLENAISVYSYAAKSGMPIIWAKDEGFEEQIDFLKGKNLKKIYALGDSKEFIAE
                     IDSNLKNIEGIKQINKSSTNVDLIKKFYDEKDIKKIYTAKLDFGSRSDVNEYISLGVV
                     SAKENMPILICSDNLSRAQDKFLKDSNINDVVEVGYTVGDYSLFKSIFNLTFLSCIVL
                     ILLLLLITFRALRYESK"
     gene            5593..7152
                     /gene="murJ"
                     /locus_tag="PC466_000416"
     CDS             5593..7152
                     /gene="murJ"
                     /locus_tag="PC466_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein biosynthesis integral membrane protein
                     MurJ"
                     /protein_id="HDF2767846.1"
                     /translation="MSKTAKAALWIMAATMFSKVLGFLRELVLANFYGTGMYADVFVL
                     TLNIPGLIIAVIGSAVATTYIPMYFETKKRLGDEGALKFTNNVLNICYIMAIVIAIIG
                     LLFTEQFVTVFAAGFRNDPAKFQAAILFTKIMISGVLFLSGSKIFSSFLQVNDSFVIP
                     GLIGIPYNIIIIAAIALSAGKNVWILPAGALLAMASQLLFQLPFAFKKSYKYKPYINL
                     KDESIKELVNLVLPMLVGVAVGQLNIFVDRLLATTLGDGKLSALNYANRLNEFVMALF
                     VTSIITVIYPKLAKMSGKDDKEGFISTIVKSSNCIILVVLPISIGAIILAEPLVRILF
                     QRGKFDALSTDLTSIALRLYSLGLLACGVRDVLYRAFYSLSDTKTPMINGSIALIINI
                     VLNLILIRPLGHAGIAISTSTSNIITVILLFISLKKKNGYFGGDKIIKTGLKSLVASG
                     VMAVATLLIYNNLYAFMGSGTIKEIISVGAGVLGGASVYTVLIVLFKVEEMDLAFEFL
                     RKGKQKLLRRR"
     gene            7194..8900
                     /locus_tag="PC466_000417"
     CDS             7194..8900
                     /locus_tag="PC466_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HDF2767847.1"
                     /translation="MDYKNNYEMWLNSPYFDEQTKNELLSIKDDEKEIQDRFYKNLEF
                     GTGGLRGIIGAGTNRINIYTVRRATLGVLNYIMKTQGEEGKQKGIVIAHDSRYMSREF
                     CIEVAKTLSAYGVKAYIFEELKPTPELSFAVRYLKCAMGIVITASHNPKEYNGYKVYD
                     SDGGQICIDMANDIIAEVNKIDDYSTIKSIDFEEALSKNLITILDNEVDDEFIKAVKK
                     QVLRQNIIDEYGKKLKIIYTPIHGTGNKPVRKVLNECGFENVMVVKEQELPDSNFSTV
                     KYPNPEEKSVFNIAIEMAKNNDTDLIIGTDPDCDRVGIVVKDSSGEYVVLNGNQVGSL
                     LVRYILESLVEENKLPKNNPTIIKTIVTSELGAKIAKAYNVDCLNTLTGFKFIGEKIK
                     AFEESNDRSFIMGYEESYGYLIGTHARDKDGVVSSLMICEMAAYYSSKGMNLYEALID
                     TYNKFGYYKEDLKSVTLKGIDGIKKIKEMMLYFRSVKIDNVADVKVDKILDYKDGVDD
                     LPKSDVLKFLLEDGSWIAIRPSGTEPKIKFYFGANSDNQEDVEFKLNNLISYILNVVD
                     SI"
     gene            8922..9995
                     /locus_tag="PC466_000418"
     CDS             8922..9995
                     /locus_tag="PC466_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-1-phosphate guanylyltransferase"
                     /protein_id="HDF2767848.1"
                     /translation="MKVYNVIMAGGGGTRFWPLSRQEVPKQLINLSGEDALINETINR
                     IDSLAKKDDLFIVTNEKQLEALKDIVKDKCLDSNILPEPCARNTAAAIGFAAFNIMKK
                     YGDGVMCVYPADHYIKDEKEFKSILEKAIYIAENNDKLVTIGITPTFPSTGYGYINFN
                     RENTIEDVAYEVVEFVEKPNYEIAKEYVNSKKYVWNSGMFVWKVSKILEDFKRYLPKV
                     YEKLEYISKYLGTKEEMEKIKEIYPTIQSISIDYGIMERSNDVIVVPGDFGWNDVGSW
                     DSLGAIYPTDDEGNIKRGENITIDTKNSIIYSDDKLISTIGISDLIVVSTNDAVMVCR
                     KDKAQDVKKIVEQLKEEDRQEYM"
     gene            10007..10729
                     /locus_tag="PC466_000419"
     CDS             10007..10729
                     /locus_tag="PC466_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDF2767849.1"
                     /translation="MIPKKIHYVWFGGPKGNIENICINSWKEKLPEYEIVEWNEKNFD
                     IEKEIKGNKFLEECYKRKLWAFISDYTRIKVLYEQGGVYMDTDMQILKDITPLLENNR
                     LICGYEDDREYINGAIIGVEKGHPFLKDLLEYYEKEVLTSSLFTIPKIMTHLMEKNYK
                     KIDPNNYEEGIRVYDKEYFYPFGFKEDFTPECITENTFGIHWWGKSWAKKRNYFLESK
                     HLTGVNKIWKCCKIFASNTLRS"
     gene            10745..11902
                     /locus_tag="PC466_000420"
     CDS             10745..11902
                     /locus_tag="PC466_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide polymerase"
                     /protein_id="HDF2767850.1"
                     /translation="MKTLNDDRNIMIRKYLYIFVLFIILLRKYMISFIDPNIDIGMIK
                     SALFYSSIGILMLLFLFDKRKSITEMVLVGVCVLLYLLNREGAILLIVLLAVSAKQID
                     DKFIVKNYLIISACFLMVAILLFNLFPSLIFNQEVHYRYIEKIDMLVTRMDFGLGNPN
                     SVFYHMVTIYAAYIFLRYKDYNKWDRIILFGSAFFVYQTTYSRTGFFTILAGLIFVEI
                     IRWIDIKKIKGLPMLLKTLPIILTLFSVIIGTIFDKSTLLNRLLASRPKFWHVYLAEK
                     GNFLKPFGNSYSPAIKATNPLDSSYVYIISVLGVVACILFMYLMYKGIESFIEKDKKA
                     YLVALFIFLLYSFAENLLLEASFSFAVVLLIKEVILNDKREIDLWKMKSRR"
     gene            11905..12744
                     /locus_tag="PC466_000421"
     CDS             11905..12744
                     /locus_tag="PC466_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDF2767851.1"
                     /translation="MLISLIMPTLNRYDDIYLLMDSLENQTYKNFELIVVDQNDNSKV
                     KEIVDKYIDKLDIKYIKSSKKGLSYNRNVGIDNAVGQIIGFPDDDCVYENDTLEKVIN
                     FFNKNEDYKIYSCKTMDSNKVDAFKKMYDGTCDITSSNVLDTITSITFFIDFEGKDYT
                     RFDEKLGVGGEFGAGEEIDYVLNLLSLGFKGKYFGNDIIYHPAKKHSKSKEKYQKDYN
                     YGRGFGALCKKEIVYRKNYTFAKVMVSKLVRNIGGLILSSNRDYHSATIKGRINGFRQ
                     YKL"
     gene            12759..13934
                     /locus_tag="PC466_000422"
     CDS             12759..13934
                     /locus_tag="PC466_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-glycerol glycerophosphotransferase family
                     protein"
                     /protein_id="HDF2767852.1"
                     /translation="MDKVKFLINMLLAFFIYPFNKHKFNGRDIWLIGGHSGDIYNDNS
                     KFFYEYMLKEHNDVETYWVVNKDSKVFDKIPGKKLIRGSVENYLYYYNSKAIVFSHAP
                     SADIAPYNFAVPVLNYFHKKTIKVFLNHGTISFKKRKPMNKKFKNIIDNLYKSYNIVT
                     ASSEFERNVMVNDWGMLDDSVYIIGNARYDNLPTNEVAQTRDILYTPTWRDWIKFSSG
                     KFTDTDYFKNIMNFLNDDKLNKILDEKDINVKIYMHHLMHEFIDDIKENITGKRIVFL
                     DKGVTLANEIRKSAANITDYSSVAIDFLYMNRPILFYQFDLDEYMEKVDSYIDLKSEM
                     FGSLAYNNDEAVNKLIDIIENNFEVMDNQKNERNKFFRYNDNKNCKRIYDCVLSKIK"
     gene            13963..14712
                     /locus_tag="PC466_000423"
     CDS             13963..14712
                     /locus_tag="PC466_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDF2767853.1"
                     /translation="MKKNLVSIITPMYNSEKFIEATIKSVLNQTYQEWEMLIIDDCST
                     DNSPNIVKSYMQQDSRIKCIKTETNKGVSNARNLALSKATGQFIAFLDSDDQWNSSKL
                     EKQVNFMLENDYVISFTSYELMDENDKKLNKVIKVPPNVDYKRLLKGNILGCLTVVID
                     KSKLDFEIRMSGVRHEDYVLWLSILKKGHIAHGINEVLALYRKSSNSLSGNKIKAAMW
                     TWNIYRNIEKIPLYKAIYYFINYGINGIKKS"
     gene            14734..15642
                     /locus_tag="PC466_000424"
     CDS             14734..15642
                     /locus_tag="PC466_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDF2767854.1"
                     /translation="MYKYKFTVFTPTYNRAHLLENLYNDLKAQTYDFNDFEWLIVDDG
                     SSDSTKELVEKFISENKLNIRYIYKENGGKHTAINLGVKNADGELFFIVDSDDGLIKD
                     SLEIANDEWDSLENKEGFSGVVGLCVYPSGDLIGTEMPEDKKICHFADLYFKYGVKGD
                     KSIVFVTDELIKFPFPERKEVRFLPESVVWNEMSKYYKVICVNKPMIIRDYLDDGLTK
                     NILSKNALRGRALEFLYLINQNTYPLSRYPYMWIKNYINLARYSLLSDSHYFGELRKV
                     SDKLLYLALFPLGYYKYIGQRKLVSK"
     gene            15690..16442
                     /locus_tag="PC466_000425"
     CDS             15690..16442
                     /locus_tag="PC466_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDF2767855.1"
                     /translation="MNEPLVSIITPVYNSEEFLSETIKSIQNQTYKNWQLLLVDDCSK
                     DNSSEIIKSFRKEDARIKYIKLEKNSGAAVSRNVGIKNAEGRFIAFVDSDDLWDSRKL
                     EIQIEYMLKENVGFSFTSYRYMRQDGSKTNKVARAPKKIDYEGLLRNTIIGCSTVVID
                     KEIVGEFSMPLVRRGQDTATWLQLLKKEKYAYGIQEDLVNYRLVGNSISSNKIKALKR
                     TWNTYRNVENLSLPKSLYVFCFYVFNAIKKRV"
     gene            16420..17763
                     /locus_tag="PC466_000426"
     CDS             16420..17763
                     /locus_tag="PC466_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose/GDP-mannose dehydrogenase family
                     protein"
                     /protein_id="HDF2767856.1"
                     /translation="MPLKKEYKFYILGGKKMKIAIAGTGYVGLVTGVCLAEVGNENVV
                     CVDVDEQKVKSMKLGIAPIYEEGLEELMVKNYNRGRIDYTTDYKKAYEDVDVILIAVG
                     TPERSDGSANLDYIKAVAKQIAETVTKDTLVVIKSTVPIGTNEEIEDYINRNLKNNVK
                     VELASNPEFLSQGTAVKDTLYASRIVIGVESEWAREILEEIYKPFNQPIIVTNRNSAE
                     MIKYASNNFLALKISFMNDIANLCEIAGANIEDVALGMSYDDRIGSKFLKAGIGYGGS
                     CFPKDTKALHWLSEHNGYELKTVKAAIEVNESQKLKLVRKASKLVESFQDMKVAVLGL
                     TFKPDTDDIREAPSIPNIKYLLERGARVTVYDPIGVNNTKKIFGDSILYADSVDDAIE
                     DAEICFIMTEWKDVLNYDIHKYKEKMKNPLVLDGRNCYKIKDMEELGIEYYSIGR"
     gene            17769..18860
                     /locus_tag="PC466_000427"
     CDS             17769..18860
                     /locus_tag="PC466_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDF2767857.1"
                     /translation="MKTVCYLADGSNPHTLKWCSFFKNKGYDIHVISLNGGHMEGIKI
                     YNFGSNVEELKNENISKKTGYLGSIKQIKKLVNEIKPDILHAQYASSYGFIGSLLGYH
                     PYIISVWGTDIYDFPNNGFIQKQIIKHNFRKADYIFSNSRDMAKEANKYTAKHVDVTF
                     FGVDMDRFKPMEVEKEDAFVIGIIKSLEKKYGIEYLIQAFKMLKDEYKDKKIILKIGG
                     SGSQMDNLINLAKELGIENDVQFLGRISPENVSKTFNSFDVTVFPSLREGFGVAAIES
                     EACEVPVIVTNVGGHPESVWENETGLIVEPKQPEEIKNAIIKLMENDELRLNMGKKGR
                     QFVRENYEVNLNFNDIEKIYDSIFDKYKK"
     gene            18944..20857
                     /locus_tag="PC466_000428"
     CDS             18944..20857
                     /locus_tag="PC466_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HDF2767858.1"
                     /translation="MRESIDLEKESFFNRLFKKYKFRHLTLLILDICSVLVAFRMSLS
                     LTGNLNAFTTNDIIISVCIYIVLHIVSFRLFKCYNTLWRYAGEEEIISIFVATLAYLI
                     PIYIINKLLGFDYPIMFYVLNTIFIIMFTSGARIAYRAIRIVMNKTYSRGKVSNILII
                     GAGDAGEMVIQELKRNSELKKVAVAIIDDDKDKIGRIIHNVKIVGTTSDIKAVVEKYN
                     VDEIIFSIANIEKRRKKEIIDICKNTNCKIKTIPGIYEIIDGKVDIKQIREVEIEDLL
                     GREPIKTNLREISNYIEGKVILITGGGGSIGSELCRQIAGFNPKELIIVDNYENNAYS
                     IQQELLRKYKNKLDLKTVIASIREEKRMDEIFNKYKPEVVFHAAAHKHVPLMESSPGE
                     AIKNNIFGTLNIAGLSSKYRAKKFVLISTDKAVNPTNIMGATKRAAEMIIQTMNAESQ
                     TEFVAVRFGNVLGSNGSVIPLFKKQIEDGGPVTVTHPDIIRYFMTIPEAVGLVIQAGA
                     MAKGGEIFVLDMGEPVRILDLAKNLIKFSGFEPDVDIKIEFSGLRPGEKLYEELLMSE
                     EGLLDTEHKKIFIGRPIDVDREKITKYLKLLREITNNEEVEKIDGIMRELVPTYIKPE
                     DANIKEIATTREK"
     gene            21056..21763
                     /locus_tag="PC466_000429"
     CDS             21056..21763
                     /locus_tag="PC466_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HDF2767859.1"
                     /translation="MMNIKNKKHILKKFIAMVLIAGVVTVEAGAITASAAEPTNSPMS
                     ATVDQCDFLNVRSGASANDAVVGKINTGDKVEVLELHSNGWIKIKSVDNVTGWVNGDY
                     LTIQGGNVDAKVQNVLNLAFKQQGKPYRWGATGPNAFDCSGFTSYVYKNGAGVNLPRV
                     SRSQATVGKKVSRAELKPGDLVFFGSGGSINHVGLYVGDSKFIHSPQTGDVVKVTSMA
                     PGTNYARRLITATRVLQ"
     gene            22065..24176
                     /locus_tag="PC466_000430"
     CDS             22065..24176
                     /locus_tag="PC466_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding glycosyl-hydrolase Cwp19"
                     /protein_id="HDF2767860.1"
                     /translation="MKKISILVLSLIMTLTMCSVSSFADSSNDKEMRAAWISTVYNLD
                     WPKTKNNEAKQKKEYTDLLDKLKSVGINTAVVQVRPKSDALYKSNINPWSEYLTGTQG
                     KDPGYDPLPFLIEEAHKRGMEFHAWFNPYRITMADESIDKLPANHPAKKNPSWVVKHG
                     NKYYYDPGLPEVRKYIVDSIAEVVQNYDIDGVHFDDYFYPGVSFNDTATYQKYGKGQN
                     KDNWRRENVNTLLRDVKASIKSIKPNVVFGVSPAGIWRNKSSDPTGSDTSGNESYVGT
                     YADTRAWIKQGLIDYVVPQLYWPIGLKAADYSKLVAWWANEVKGTNVDLYIGQGIYKQ
                     GQSSYGGQNIAKEIVQQVTLNRKYSEIKGSMYFSAKDIANSTSIQKDLKSLYSSSEEP
                     VTPPSNVKVEKLRGDERYDTAVAISKKGWATNSDTVVLVNGYSIVDGITSTPLATSND
                     APILLVNKDNIPTSTKNELKRLNPSKVILIGGNNSIGDKVESEIKDTLSNVSINRVGG
                     SDRYSTSLMIAKELVKTNPVEKLYITSGTGEADSLSIASKAGEEKQPIVLVSKDNVSD
                     EVYNWISDLKVKDAYFIGGNLSISDSVINKLDKVITNDVSKNRIAGENREETNGKVIQ
                     KFYPNAEYSSMFVSKSNQLVDALTSGPLAAKLKSPVVMLGNSVTSAQKTALEPKKTAL
                     VYEAGDGINQNTLNTFLNLVK"
     gene            complement(24374..25339)
                     /locus_tag="PC466_000431"
     CDS             complement(24374..25339)
                     /locus_tag="PC466_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HDF2767861.1"
                     /translation="MSKLKKFVILLAFLVVIFPISVYGYFYYKLSAIHDSSISSDLLD
                     NNDHKNEDGIINILLMGTDARPNEDSSRSDAMMILTIDNKHNDIKLTSLARDSYVDIP
                     GHGKQKLTHAYAYGQADLLIQTIEENFNIDIQNYACVNFESFMYIIDAIGGVEVTVEK
                     GEIRELNKFIPETYKWNKSDDKGSIQYIRNSGKQTLNGYQALSFARIRHNDTAFARDG
                     RQRQIIQAIIKKTETLPVTKYPGLLDAVLPYVKTNMKPNAILSLGAQVLKMGDLNIKQ
                     FEFPIDDEIHSTGGIYGKAGWVLRFDPDTLDILHDFIFNDIEFKQ"
     gene            complement(25624..26580)
                     /locus_tag="PC466_000432"
     CDS             complement(25624..26580)
                     /locus_tag="PC466_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HDF2767862.1"
                     /translation="MSGLKKFVIFLALLVIAFPVSIYGYVFTKLKTIQDDSINTEALS
                     SNDYKNEENITNILLLGTDARPGEEVSRSDAMMILTIDNKNKSLKLTSLNRDTYVDIP
                     GRGEQKLTHAYVYGQANLLIETIEENFQLDIQNYAVVDFFSFMDIVDALGGVTVTVDK
                     SEIRELNKFIPETYKWNKNDNKGSLKYIRNSGEQKLNGYQTLAFSRIRKNDSTDERDR
                     RQRSVIQSLINGVKDLPVTKYPNLVNTILPYVKTNMNPNEIISLGKELLSIGNLNLKS
                     MEFPLSTENGRKIGNAGYVIPFEEYELDAMHDFIFKDIMVED"
     gene            26948..27736
                     /locus_tag="PC466_000433"
     CDS             26948..27736
                     /locus_tag="PC466_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDF2767863.1"
                     /translation="MIKLIATDLDGTLLDEKSEINPEFYKVFKKLRERGIMFSAASGR
                     QYQNLIKKFEDIKDDMMFISENGTLVVYKGKEILSNPLNKELVNEIIETTRSIKGKKI
                     VMSGKKYAYIESKDEAFIQEVSTYYAKFKIVDDLTKVEGDILKIAVFDFKGAEHNNNI
                     YFEKFSDRAQVCISGVEWLDLTAKGANKGSAIKKVQKMLDIKYEETMVFGDQLNDVEM
                     MKSAYHSYAMENANEHLKQIARFRAKRNTENGVVDKIKEVIKIG"
     gene            complement(27859..28329)
                     /locus_tag="PC466_000434"
     CDS             complement(27859..28329)
                     /locus_tag="PC466_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4358 domain-containing protein"
                     /protein_id="HDF2767864.1"
                     /translation="MKKILILFFSIILSLGMVSCSSSGDYKNVSTSKIKKALKSSDLL
                     IKESKIFDAKDFNYFNDVEEDIIQGFVINSSEKLSLEDIIVIKTDEVDKIYKTLENYK
                     KDMIQAPFGEGHGEKINSEIANNTIIEKAGRYVYLISAENATQIENKILNIIKK"
     gene            28468..29112
                     /gene="uppS"
                     /locus_tag="PC466_000435"
     CDS             28468..29112
                     /gene="uppS"
                     /locus_tag="PC466_000435"
                     /EC_number="2.5.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="di-trans,poly-cis-decaprenylcistransferase"
                     /protein_id="HDF2767865.1"
                     /translation="MRIPKHVGIIPDGNRRWASQNGMTKDKGYESGIDPGLESYRLCR
                     DLGCEEVTFYGFTTDNTRRPSVQTKAFTKACIDAANILIDEGAALLVVGNTKSPMFPE
                     ELLPYTNRIKAKEGQIKANLLVNYGWYWDLNNISGVENVNKNNIQDYIQSFDVSRLDL
                     IIRWGGRRRLSGFLPVQSIYADFYVIDNYWPDFKSDDIKDAFSWYDTQDVTLGG"
     gene            29155..30060
                     /locus_tag="PC466_000436"
     CDS             29155..30060
                     /locus_tag="PC466_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDF2767866.1"
                     /translation="MKKKLLDGKITLIICKSVKIYTKKGEEMSKGNNNNNSRNKSKKT
                     SHLNRKKRKLNKKKLAVLICFTVLFLFIAFKATQGVVALVKSMDKSNKTSQQQKVNSE
                     QFDLGNEEENKKKKYTVFIDPGHGGNDKGTESKTSNRYEKDLNLQIAKKLANKLSKQK
                     DIQVVVSRTDDTYISLKDRAILANNSSADVLVSIHLNAEKNGNTATGIETWYRNKATD
                     GSKELAQTVQSTIVSYVKVRDRGIVENNFEVLRESNMPAILIECGFLTTPSEEQKIIN
                     EKYQDQLAEGIVQGVLSYLDSKGNK"
     gene            30375..31922
                     /locus_tag="PC466_000437"
     CDS             30375..31922
                     /locus_tag="PC466_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDF2767867.1"
                     /translation="MNKNSMTKIYSLNKIIFIIIGILGIVLLTRHIEVDIKVLILILL
                     TLFSINVFISYLKIKLYEDKINLGLINNSDKFINITKDENFLKHVQNYIISNEKENCV
                     MACFDLCRLKLINDIYGYELGDEVLNNILSNLKNYFGKEAIYGKLKSDVFVLIIKLEN
                     REQKIPYLVNLIKNKIMILSQIDSFKMDINIEASIGIYKFNNNEIDIKKAIDNADMAR
                     LKSKGLKHIEYVEFDNAMEEEIQSIMKIERDLFLAIKNKEFVIHYQPKVDSSTGNIIG
                     SEALIRWLHPSLGMVGPNKFIPIAEKNGLINNIGRWLIQEVFITINKWISEGINVLPV
                     SINLSRVELYKNDLVDFFKLMFNTYNIPKELIELEITETTALRDVKFISERLYEIKSL
                     GMNISLDDFGVGNSNFINLKGIPLDIIKIDRSLILDIVTNTKTKFMVKAIINLSHDLN
                     VTVICEGVEDMHQVKVLSELGCNFIQGYVFFKPLDEMNYKKLLTDGSYINLKDTLLDK
                     CMTVEEE"
     gene            31925..32323
                     /locus_tag="PC466_000438"
     CDS             31925..32323
                     /locus_tag="PC466_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HDF2767868.1"
                     /translation="MISEDVDYSIRIIRAIFNNGEDKPIDAKMILKSEDIPILTLYRL
                     LRKLCANNILTFNKEDGKTYMLNVSLDTISLRTIVEVIDGKIYINKCTRYVSNCSNCL
                     KGCKVNRELLEIEKEIYKLLSRKSIRQILE"
     gene            32363..34096
                     /locus_tag="PC466_000439"
     CDS             32363..34096
                     /locus_tag="PC466_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
                     /protein_id="HDF2767869.1"
                     /translation="MDDISQDNFLLSKEYENSLDVDTKKASGIYYTPKIIVDYIVKKT
                     LKNHDIIKNPYPRILDISCGCGNFLLEVYDILYDLFEENIYELKKKYDENYWTVDNIH
                     RHILNYCIYGADIDEKAISILKDSLTNKKVVNDLDESDIKINLFCCDSLKKKWRYKFD
                     YIVGNPPYIGHKKLEKKYKKFLLEKYSEVYKDKADLYFCFYKKIIDILKQGGVGSVIT
                     PRYFLESLSGKDLREYIKSNVNVQEIVDFLGANIFKNIGVSSCILTFDKKKTKETYID
                     VFKIKNEDICINKFETLEELLKSSKFEHFNINQRLLSDEWILVNKDDETFYNKIQEKC
                     KYSLEDIAISFQGIITGCDKAFILSKDDVKLNLVDDKFLKCWIKSKNINKYIVDKSEY
                     RLIYSNDIDNENTNKKILDEIIGLYKTKLENRRECKSGIRKWYELQWGREKLFFERKK
                     IMYPYKSNENRFAIDYDNNFSSADVYSFFIKEEYLDKFSYEYLVGILNSSVYDKYFKI
                     TAKKMSKNIYDYYPNKVMKIRIFRDNNYEEIENLSKQIISILLNKSIDKGKVEKLQIK
                     MDNLIMDSLGI"
     gene            34328..35539
                     /locus_tag="PC466_000440"
     CDS             34328..35539
                     /locus_tag="PC466_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HDF2767870.1"
                     /translation="MKGLVLEGGGTKGAYQIGAYKALRELGIEFQGVTGTSIGALNGA
                     YIIQNDIEVMEDIWLNYDYTHFMNIDRETYERFKNVDFTTKNLNAVFELINKARKNEG
                     IDISPLRQLMETTLNEDIIRKSKKDFGLVTVWWDKKINPYPLYIEDIPKGRLIDYLIA
                     SSSLPIFQTNMMDDKLYLDGMFCDNMPIGLLEDKGYEDVVVIRLIDDFIGKMNLNRHQ
                     NINIKTIIPSEYLGGSLNKDRDNVEKNIRLGYLDTMKAYERCTGIKYYFDVEYKYNEE
                     YCFDKFRSMSNETIQYICNLLNIKRDASLRTVMESVIPKLGEVLGLPKDFSYKDLFYC
                     IYEKKLEENNINRIKLYDFNKVIDVVNTNIDSNRNLASNFEVRPKISIKKNKNTKLLT
                     NCIIKDIKNQS"
     gene            35731..35991
                     /locus_tag="PC466_000441"
     CDS             35731..35991
                     /locus_tag="PC466_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr family phosphocarrier protein"
                     /protein_id="HDF2767871.1"
                     /translation="MEKVVSIKNASGLHARPAGMFVKKAAEFKSTVEVVAKDKTVNAK
                     SIMGIMSLGLAQGEELKLVVNGEDEEVALAAMVELVESGFGE"
     gene            36344..38056
                     /gene="ptsP"
                     /locus_tag="PC466_000442"
     CDS             36344..38056
                     /gene="ptsP"
                     /locus_tag="PC466_000442"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HDF2767872.1"
                     /translation="MAYKGIGASPGVALGKALVVEHSELVIEKKSIDNVEAEIAKLED
                     AVAVSKEELVKVKEKASEELGAEEAEIFEAHLLVLEDPELIGSAIDKIKTESVNAEYA
                     LNEIKEMFVSMFESMDNEYMKERAADIKDVTNRILRHILGIKVVDLSALSEEVVLIAH
                     DLTPSDTATMNKKMVLGFLTDIGGRTSHTAIMSRTLEIAAIVGLNDITSKVKDGDFVV
                     FNGDTGEVIVNPDEETINKYTELKAKYEDERKALQLLKGKPSVTLDGKHVELAGNIGT
                     PNDIEGLIKNDAEGVGLYRTEFLYMDRDSFPTEEIQYEAYKAVLEGMDGKPIVIRTLD
                     IGGDKELSYLSMEPEMNPFLGYRAIRLCLDRKDIFKTQLRALYRASIHGRLRIMFPMI
                     SSLEELLQAKEVVKEVLAELDSEGVAYAKDVEIGMMIEVPSAAVISDVLAKHVDFFSI
                     GTNDLIQYTCAVDRMNQKISYLYNQFNPAVLRLIKTVIDNAHKEGKWAGMCGESAGDQ
                     KMIPILLGMGLDEFSMSPISILPARKLITSVKESDMKKLADDVLNMGTAEEIKSYIEK
                     TFNI"
     gene            complement(38848..39513)
                     /locus_tag="PC466_000443"
     CDS             complement(38848..39513)
                     /locus_tag="PC466_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2767873.1"
                     /translation="MKGNIVQYNFADIEEEVYSLDYAIAWNTDEENVNIIPFTNKFCK
                     ESIESFCLGKINNFVEILNEGFVENHHYVHLDKMISVPKKKVNLVYQQDTHGYLLRDD
                     NDNLIPAKITSEQSKSISSKMELFCAGEEKCLINILLKADPSYILDVDSIKDKNILNL
                     GYESIDRYKEYNFDDDKILIFFINKKRYSVIMKKTNNSDNDLVSRNNAIKELFTNKAG
                     NLN"
     gene            39857..41287
                     /locus_tag="PC466_000444"
     CDS             39857..41287
                     /locus_tag="PC466_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4116 domain-containing protein"
                     /protein_id="HDF2767874.1"
                     /translation="MDIKNKIKSIFLPEKNDYLDDEEFEYDIENNEEDLKEDNKVHLN
                     DLSRVKYDYRELKDIENQTEEMCLLAVKQDGTIIEFVKDKTYKVCMEAVKQTYKALKY
                     ITNQNEDICIEAVKQNYRALYYINNKTENVLIEAIKNASTYDVMEVFKFVEDQTEDVC
                     LAFIERASKNDVAEILKGIKEQTPAICLEAVKKDGKSLAYVKEQSNSICLEAVKENYS
                     ALSCVKEQTEEICIEAVKQNDFALYYVNEQTEKICMEAVKRSYMALQYVNKQTEEICL
                     EAVRIDGRALQYVKEQTEEICLESVRQNGKVLQYVKKQTENICIEAVRGSFEELEIKE
                     ILSYVKIPTERIFVEAVKQNGKILKYVENQTELICLEAVRENYNALAYVKEQTEEICL
                     EAVNQSYEALKYVKEQTEEVCLKAVKQDYRMLKYVNNQTEKICLEAVKQNYRALEFVD
                     NQTEKVCLEAVKQNRKALQYVKQKQS"
     gene            41655..42233
                     /locus_tag="PC466_000445"
     CDS             41655..42233
                     /locus_tag="PC466_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HDF2767875.1"
                     /translation="MFKRYAEKMTSVLICNNMIDNNESKVYSYGFEILIAFIVNITTM
                     LFIGFLFGKFTYVLFFLMCYCPIRQFSGGYHADNYFRCLLTFIFIILSTILIIENINI
                     DLFKNIIMIIASVSWVGICVLCPIEHRSNPISDREKFVYKKTAIFISTVVLLITILSL
                     SLSIFVDYFTYSAFAMFWIFVMLVLGKLKAKV"
     gene            42263..42409
                     /locus_tag="PC466_000446"
     CDS             42263..42409
                     /locus_tag="PC466_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic lactone autoinducer peptide"
                     /protein_id="HDF2767876.1"
                     /translation="MKKFIVRFMKFASSLALSTAILSANSTCPWIIHQPKVPKEISNL
                     KKTN"
     gene            42714..44093
                     /gene="scfB"
                     /locus_tag="PC466_000447"
     CDS             42714..44093
                     /gene="scfB"
                     /locus_tag="PC466_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioether cross-link-forming SCIFF peptide
                     maturase"
                     /protein_id="HDF2767877.1"
                     /translation="MSMIHKFSMNGYNIVLDVNGGAVHVLDDVAYDLLDFYKEKSKEE
                     ILEILKSKYQEEKINEAYEEILNLEKEGLLYTEDTYQYHPSFVHREPVVKALCLNVAH
                     DCNLKCKYCFAAQGDFGGEKELMSFEVGKAAIDYLIANSGSRKNLEIDFFGGEPLMNF
                     EVVKQLVDYGRSVEKDYNKNIRFTITTNGVLLNDEIIDYINENMHNVVLSLDGRKEVN
                     DNMRPTLNDKGSYDITLPRFKKLVEKRAKDKYYYIRGTFTRDNLDFSKDVMHFADLGF
                     KLTSVEPVVGDESNPYALREEDLPKIFEEYEKFAVEYADRQLQGDGFKFFHFMIDLNQ
                     GPCVIKRITGCGAGNEYLSVTPNGDIYPCHQFVGNEEFKMANIFDEEIVLPENLKNMF
                     REAHVYTKEECKQCWNKFYCSGGCHANAINFNNDISKPYELGCEMQRKRTECSIMIQA
                     KLMLEGATN"
     gene            44122..44619
                     /locus_tag="PC466_000448"
     CDS             44122..44619
                     /locus_tag="PC466_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HDF2767878.1"
                     /translation="MIRDYLEDKPLIDESVFVAKSADVIGNVKIGKDSSIWYNAVVRG
                     DEGPITIGENTNIQDCSIVHGDTETIIGNNVTVGHRSIVHGCKISDNVLIGMGSIILD
                     NAEIGEYTLIGAGTLITSNKKFPPGVLIMGSPGKVVRELTEEDKKYIDESYEWYLEAA
                     QNQKY"
     gene            44917..46581
                     /locus_tag="PC466_000449"
     CDS             44917..46581
                     /locus_tag="PC466_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/ABC1/UbiB kinase family protein"
                     /protein_id="HDF2767879.1"
                     /translation="MRISYRNLKRYREIGYVLIKYGFSFIVERLNIEGIAYKIPLFDP
                     PEEIKNMTTGERMKRVLEELGPTYIKIGQILSTRKDLLDQDIIDEISKLRDDVEKFDS
                     NIAIDIFKEEVGLSIEEIFLEFKEEPIAAASIGQVYEGVLKTGEEVIVKIQRPNIEKI
                     IKSDLEILRTIANTLKDLKKDFNLDLVQMIEEFQTQLMRELDYTFEAINATKFSRIFK
                     NSDEVYIPKVYSEYNTKKILVMEKVNGTKLSDVEKIRRLGYNTKTIVEIGVRSFFTQV
                     LSHGFFHADPHPGNIFVVAKNKIAYIDFGMIGIIDNKTLNQLNEIALAGVEKNVDKII
                     YLLIEMDALNGEADIKGLRQDLLYLIHYYYDISIEKINVTDILNELFRFFRQYKIVMP
                     AQFVTLAKTVITLEGTSRTLNTDFSFGSMGKEFMKHHYKSKFNPKNVVLSSRQNVEEI
                     LLDIKTIPKQLKAILKNIERNNIKMQIEDVKMTRLENCIIELTSQISLSLVLASIIVG
                     SSLIIASPNIENNIWIKFTAIAGFFISFIIGLCLVIRSIRSKYKKD"
     gene            46594..49044
                     /gene="recJ"
                     /locus_tag="PC466_000450"
     CDS             46594..49044
                     /gene="recJ"
                     /locus_tag="PC466_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HDF2767880.1"
                     /translation="MKKWILKYKGKIEESEFSKKLNISPEICQILKNRGICTEKDSEI
                     FMNPSLDYLRDPFLMKDMQKAVDRIKLAVEKNEKIWIYGDYDVDGVSSTSILCLYFKS
                     IGYNVDYYIPNRLEEGYGINEDAIKLISSRGCDLIISVDCGITSVSEVNTANDLGIDV
                     IITDHHECQSEIPSAFAVINPKQEDCNYPFDSLCGCGVAFKMIQALTPKEEFKTSMYN
                     YLEIVTLATICDIVPLIDENRIIVKNGLKSMKEGKNIGLRELIKVCGVESDKIGSSHI
                     GFAIGPRINASGRLGYSYLGVELFTTQSQEEAVEIASILEEKNNERQMIEAKMYHEAE
                     EMLKSNSRYNDDKVLVLAKEGWQHGIIGIVASKLTEKYYKPTILLGIENGEATGSARS
                     IKGFNIFEALIKCKDLMTKFGGHEQAAGLSLDSDNVEILANEINKFADYNLTEDDMIE
                     NVNVEFELQENVINLNLVEELHKLEPFGLNNPNPRFIVRNYILKDLKVIGKNQQHLKL
                     SIEKEKSYECIGFNMSHLKSMYKVGDKVDVLFQLDENNYMGNRKVQFLLKDIRLARPK
                     SASNDKLSLKLMSKIIPKDTQSLYNISVSDFELFDGNTDINIFDYFEKDTLIISNSIN
                     GFYRAMSDISLIDLDFNINYNIIEDVSKNTDKLELIFSPNIDKIDLKRYNNIILYDYL
                     YNKGEYSYIYENKREESEIIKYYNKTDLLYLKNVVSNIVPSRDEFITIYKQALIKKEI
                     DLDMVNIRETFNVIPLKFFTILNVFRELNLLDFNLNYEKNSVLIRILPKPQKKLDLNE
                     SLILNNLKNLEKQYNSSY"
     gene            49057..49569
                     /locus_tag="PC466_000451"
     CDS             49057..49569
                     /locus_tag="PC466_000451"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HDF2767881.1"
                     /translation="MDLKNFIRNIDDFPKPGIDFKDVTTLFKDGDAFKYAVDSIVEEL
                     KDKDVDLVIGPEARGFLMGTPVAYALGVGFVPIRKPGKLPGEVESYEYGLEYGTDTLE
                     IHKDAIKKGQKVAIVDDLLATGGTMEAAAKLVEKLGGEVVSMQFLIELKFLNGREKLS
                     NYDVNSLIKY"
     gene            49643..51850
                     /locus_tag="PC466_000452"
     CDS             49643..51850
                     /locus_tag="PC466_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003229747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HDF2767882.1"
                     /translation="MHDKELQEIIEKIKVYAPNANFEMVEKAYNLAKKAHEGQYRKSG
                     EPYFIHPLAVANILIEMELDIETITAGLLHDVVEDTEYTYEDIKKEFGKEVADLVDGV
                     TKLGQIKYRSKEETQSENLRKMFLAMAKDIRVILIKLADRLHNMRTLKYMPPEKAKYK
                     AKETLEIYGGIAHRLGISKIKWELEDRALRFMDPEGYYDLVSRVSMKRSQREDYIQGI
                     VELLKDKFKDLSIPCDVYGRPKHFYSIYRKMQKKHKTFEEIFDLTAVRILVDNVKDCY
                     AVLGIVHTLWRPIPGRFKDYIAMPKPNMYQSLHTTVVGPDGEPLEIQIRTHEMHNIAE
                     NGIAAHWKYKEGISSKESKVEEKLQWLRQMMEWEKDLKDPQEFMDALKEDVFNSQVYV
                     FTPKGDVIELPAESTPIDFAYRVHTNVGNKCVGAKIDGRIVPIDYKLQNGNIVEVLTS
                     SNSNGPSRDWLNIVKTPNAKSRIRQFFKKERREENVDRGNTILEREFKKHDIPQKDPL
                     VEKYMALVAKKFNQPSVEDLIATVGYGGIMSSQVVSKVKDLYLKEVKKAKKEQQIQEE
                     DLNKHNISETEYSKKRKKNASQGIIVKGLDNILVRFAKCCNPLPGDEIVGYITKGRGV
                     AIHRADCPNANNNGDFFQNRLVEVSWSSAGKGKFEAEIQIKAIDRRGIVNEITHIVAM
                     DKLSLNGINARKGKDSIVSINLLVEVNDTEELKILMKKLKAIPGVESIYRMTN"
     gene            51875..52324
                     /locus_tag="PC466_000453"
     CDS             51875..52324
                     /locus_tag="PC466_000453"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003517065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HDF2767883.1"
                     /translation="MRAVVQRVSSSKVTVDENTIGQINKGLLVLLGVTHDDKSSDVDY
                     MIDKILNLRIFEDENDKMNLSLMDIGGELLVVSQFTLYGDCRKGRRPGFSNASRPELA
                     NNLYEEFVKKAKDKGVTVGTGQFAAHMMVELTNDGPVTILLDSSKSF"
     gene            52339..52953
                     /locus_tag="PC466_000454"
     CDS             52339..52953
                     /locus_tag="PC466_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF2767884.1"
                     /translation="MIIKKFVDSYFGVNTYVLGDEKTKKCAVIDPGGSLVETLSFVKE
                     NELNIEYIILTHGHGDHIGYVKDIKEKTGAKVVAHVDEKELLNDKNKNLSYTMRCGAQ
                     EFDADIYVSDKDKLELGELKMTFLHTPGHTQGCMCIRVEDEMFTGDTLFAGSIGRTDL
                     YSGDFNQMEKSLKKLCKYEDAVRVYPGHGPTSTLGVEKKTNPYM"
     gene            53044..54600
                     /locus_tag="PC466_000455"
     CDS             53044..54600
                     /locus_tag="PC466_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coproporphyrinogen III oxidase"
                     /protein_id="HDF2767885.1"
                     /translation="MLYVFLKGHDYKYEVAELIKLFTSEFKFKDSNANNNIESKHLIN
                     RLIYENGVLFSSTEYYENGNLKYESIQNIENMNLEFLDGFDSSKTIEEFLNRLDSESK
                     RNFKKLCKENIKKSMFVVLKQVFNSYVPWGILTGIRPVKIVHNLMDKKLDDNSIRTIL
                     KDNYFIIDKKIDLALEIAKRERLFMYPIDKNKISLYVSIPFCPTRCVYCSFPSNSLKQ
                     FGHLKREYVYKLIEEIKGFAKVIKETKKEVETLYIGGGTPTTLDEEELDLLINSLFNE
                     LDLSKIKEFTVEAGRPDTITEQKLRVLKKHNVSRISINPQTMNDDTLVKIGREHRVSD
                     LVDCFNMARRMGFDNINMDIILGLIDEELNMVKNTLEEIKKLSPESLTVHTLAIKRAS
                     NLNINMDRYKEHLTQYEEMVKMIDLSMKYAKDMGLNPYYMYRQKHMLGNLENIGYAKE
                     GYECIYNIQIMEEKQSNYALGAGAISKFVYVDEDRIERVENVKNVEQYIERVDEMIKR
                     KKEEVYKNVD"
     gene            54590..55852
                     /locus_tag="PC466_000456"
     CDS             54590..55852
                     /locus_tag="PC466_000456"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HDF2767886.1"
                     /translation="MLTKAPRGTKDITPKEAYKWRYVENKFREICALYGYEEMVTPIF
                     EHTELFKRSVGDTTDIVQKEMYSFKDKGDREITLKPEGTAGVVRAFIENKLYADTQPT
                     KLFYVTPCFRYERPQAGRQRQFHQFGIEALGSDTPSMDAEIIALAVQFFNEVGLNDLV
                     VSINSVGCPVCRKEYNALLKEYLDSKADILCDTCNERREKNPMRVIDCKNPTCKENIK
                     DIPFIADHLCDDCKSHFDKLQEYLKEMNINFVIDKTIVRGLDYYRKTAFEIISNDIGA
                     QSTVCGGGRYDGLVEQLGGPKGISGIGFGLGIERLLLTLEGNGIEIENPQSTDIFIVT
                     IGEEANTRSFKLLKDLRQNHISADKDHIERSVKAQFKYSDKINSKFTIVIGDDELKND
                     TATLKNMKTSEQTTVKLSTLVEELKQKL"
     gene            55926..57713
                     /gene="aspS"
                     /locus_tag="PC466_000457"
     CDS             55926..57713
                     /gene="aspS"
                     /locus_tag="PC466_000457"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HDF2767887.1"
                     /translation="METLKGLKRTHYCGELREKNINEEVVLMGWVQKKRNLGGLVFVD
                     LRDTSGLCQIVFDTDVDKEAFEKAEKLGAEFVIAVKGKVCERQSKNPNMPTGDIEIFA
                     TELRLLNKSETPPIYIKDDDDVSEALRLKYRYLDLRKPSMQRNLKLRHKVMNITRNYL
                     SNNRFCEIETPFLIAPTPEGARDYLVPSRVNPGKFYALPQSPQLYKQLLMVSGMDRYF
                     QIVKCFRDEDLRADRQPEFTQIDCEMSFVEQEDVMSMIEGLLEAIFKEVLDVELALPL
                     PKMTYAEAMSKYGSDKPDTRFGYELTDISDVVCNCGFKVFADATQPGKSVRGINVKGK
                     ADDFTRKQISSLEEHAKTYRAKGLAWMKVGQEGVTSPIAKFFNEEEMNAILTKMNAEV
                     GDLLLFVADKNSIVFDALGQVRLEVANRLNLLDKNVYNLLWVTEFPVFEEDEETGTFS
                     AMHHPFTSPMDEDLDKLEEGDKSSLRAKAYDIVLNGYEIGGGSVRISNSDIQSRMFKA
                     LGFTEERANEKFGYLLEAFKYGTPPHAGLAFGLDRLVMLLAGTDNIREVIAFPKNQNA
                     VCPMTNAPTLAEDEQLEELSIKVDIKDNE"
     gene            58172..59404
                     /locus_tag="PC466_000458"
     CDS             58172..59404
                     /locus_tag="PC466_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosine permease"
                     /protein_id="HDF2767888.1"
                     /translation="MQEREELVLNPVPKEERVGWLAPLFNMLGSNIAISELMVGGTLI
                     LGMTLSNMIITSIIGNLILVAIIMIQGYIGYKEGLNTYVLAKGAFGEIGGKYLISLLL
                     GITSFGWFGVQAGVAGLSVQKIFPSVNLTLVTVILGLFMVVFALYGFKAMAKFNYLVI
                     PPLMILMVWGVFKAFSTYGVEAIYNYTPQTTMSMVEGLNIVVGLVIVGAIISPDQLRY
                     TRRVKDIWIISFLGLGIISLFQQVAAGVMSMGAPTWDITEVLANLGFGWVAFVILILA
                     SWSTNVSNAYSGGLALKTIFPNVKRNVLTLVAGLIGTIIAATGIIFKFQSFLSFLGIA
                     VPAIAGIMWCEYYFIQGRTYKHREGINWIAVISWLIGFAASYYSSKINFLIPPINGIV
                     VSMVIYYILMKCFGIKDK"
     gene            59418..60224
                     /locus_tag="PC466_000459"
     CDS             59418..60224
                     /locus_tag="PC466_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase"
                     /protein_id="HDF2767889.1"
                     /translation="MGRKVKIGIIQQHSVLGDVKKNIEKAVEMIDDLGKHGADIICLP
                     ELFATGYNLESLGGVKTLELIREHNKYIEESMSEAAKRNNVYLISPYGTLEKGSTHVY
                     NSAVIFDRKGKIMGEYCKNHLWSLEAVYFKGGEKVEVYDADFGRFGVMICYDAGFPEV
                     SRELTLKGSEIIFIPSAWRIQDEDMWDLNVSQRALENTVYTVGVNLVSNDSNLILFGK
                     SKICNPRGTVITQLDTYREKYVLSEIDLDEIKKYREDIPYLKDRKSSYNI"
     gene            complement(60336..61205)
                     /locus_tag="PC466_000460"
     CDS             complement(60336..61205)
                     /locus_tag="PC466_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDF2767890.1"
                     /translation="MDLLHLKYFQTVARMEHITKASHKLNIAQPALSKTISSLEKELG
                     VQLFDRKGRYIVLNEYGRLFLKRVDSILDLVESSKKELQDTSLENSGEVKILSPAAAN
                     VLPSLLSNFRKLYPNITFNVSHTLPSSYKKSDFDLYISSSFTKLNSENSITLTCEEIL
                     LGVSINHPLSLKDEVYLSEVSDENFIVITKGENYREVIDILCESANFKPKIAFESDSP
                     YTIYALIKSLQGVGFICGKSWGLSQDPEIKLLHIKDIEFKRYLNLSWFSENYESKAVL
                     LFKNFLINYFKNI"
     gene            61576..63003
                     /locus_tag="PC466_000461"
     CDS             61576..63003
                     /locus_tag="PC466_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp14"
                     /protein_id="HDF2767891.1"
                     /translation="MKLTKSISSMLCLALVLSLSPVAYANEISRTTVENTLVGQDRYQ
                     TAVEVSKKGWSSANEAVVVNSESIVDALAVTPFAKLKNAPILLTEKNNLNSQTEKELK
                     RLGVKKVYIIGLSSSVSNDVQKQLESNNLTTDRVGGSDRYQTALSIAKKIEGLKDISE
                     IAVVNGYTGLADAVSIASVAATNGMVILPVSDASGISSFKDFIESKNINKSYIIGSTN
                     AVSDKIKQSLPNSERIGGADRNETNGKVIEKFYTSNKLNNVFVAKDGMKNQNQLIDAL
                     AVGVLASKENSPVLIVGEQLSATQKSVFLNKNATSITQVGSGGNENAFKELKDLQANS
                     NNKRVMYVTNTDKVNIRNDATIEASVIGYLNNGDEVEVLDVLKTGWVKIKYNEGIGYV
                     SGSYLTNNKPDNSNENIKIKYVKEKDGLNVRKGPSTEDEKIGHLSYGSKVETIEIFAT
                     GWVKIKYNGGYGYVSNDYLSDTPVI"
     gene            complement(63079..63348)
                     /locus_tag="PC466_000462"
     CDS             complement(63079..63348)
                     /locus_tag="PC466_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2767892.1"
                     /translation="MKFEYYYLIQDIAGILLAFIGLRMSIIGFRILSMKGISINTLLI
                     VIKYCLFTIAGLNLLISKFGIRHWIWSVCMLIISIIINPRIKVSK"
     gene            complement(63351..64793)
                     /gene="nhaC"
                     /locus_tag="PC466_000463"
     CDS             complement(63351..64793)
                     /gene="nhaC"
                     /locus_tag="PC466_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HDF2767893.1"
                     /translation="MKMNTERKIPSFRYSLLVMLAIIALTSVGIVVFNASITTMFLLS
                     WLIVVPAATKLGYTNDEIEAFGFEVGKDAFQSNLIILSVGVLIAAWIAAGTIPTVVYS
                     GLTIITPKYFLLTTLIVCSLTSVATGTSWGTLGTSGIAMMSIGTSMGIPLGLTAGAVI
                     SGAFFGDKMSPLSDSTNLAAAVCKTDVITHMKHMFYTTGPAYVICIVLYTVIGFKYSN
                     NTIDYVQINQIKDVLNSNFHIGLVAMIPIIFLLLLLLLQKPPIISILSSAIMGLIIAV
                     FQEGEKIGDILNYMLSGFTIDTGFVYADKLLNRGGIMSMAETVLLVFVVFVIAGILQK
                     TGFLEVLLQPLITKIGKSRTKLVGSTFIVSYFANAFSSSMMFTSVFVGTLMSPIYKEF
                     KLKPQNLSRIIEDTATLGGPLIPWNSNAVFCAQTLGVSPLEFIPYCFLSWITPIISFI
                     YGVTGFTMLTYTDDEIEELEIFDTAQRRVD"
     gene            complement(64818..65984)
                     /locus_tag="PC466_000464"
     CDS             complement(64818..65984)
                     /locus_tag="PC466_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HDF2767894.1"
                     /translation="MNYNFNEIVDRSNNFSSKWSEMEKKYGTNDLLPMWVADMDFKAA
                     PCIIDSLKNRLEQEIYGYTTRPDSYNESIVNWLDRRHNWKIKSEWLIYSPGVIPAISL
                     LINELTKANDKIMIQEPVYSPFNSVVKNNNRELIISPLQKLENGNYIMDYEDIENKIK
                     DVKLFILCNPHNPVGRVWTKDELKKLGDICLKHNVKIISDEIHSDIILKKHKHIPMAS
                     ISKEFEKNTITCMAPTKTFNIAGLQSSYVILPDEKDYKLLDDAFTRIDIKRNNCFSLV
                     ATEASYNNGESWLESFLEYLESNIDFAIKYINENMPKLKVRKPEGTYLLWVDFSALGL
                     SDEELESVLVQKGKVALNQGNSFGIGGSGYQRINLACPRSMLEEALIRIKNAIK"
     gene            complement(66209..68329)
                     /locus_tag="PC466_000465"
     CDS             complement(66209..68329)
                     /locus_tag="PC466_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2767895.1"
                     /translation="MKQMELAIVSLKKDAGEIYENQIRQFLGDNLKINLYSFEEGNLK
                     FFKEKLILLSAYLKYDEIVKLSHYDAQIIVPKLTFEKNSIDMISKLEKDKIIYVYNLS
                     KDMAIETISLIHRLGIDNINILPCYPEIEFTPTDAVILTPGEKILPKFKNCEVVDLKY
                     RIIDLSCIVEIATKTKLKHLIKDDLIKKYVEKIIPTSYSTGELLLDANKFERQFDLLL
                     SIIDDGIICTNNDGIIQFYNHIARKILSINANEMIDSFVGDCIKDINFQNILTNKTPF
                     FEKLIKINHIDINLEIKHIQLNVFDGFILKMTKFSQLEKKQAKLRAQLVNSGNISKYT
                     FDDILGSSIQTINTKKIANKMAQSNSSILIIGESGTGKELFAQSIHSASRRKDGPFVA
                     VNCSTFQENLLQSELFGYDEGAFTGAKKGGKIGLFELANNGTIFLDEIGEMDLNSQSK
                     LLRVIQEKQVRRIGSNNVIDIDVRIIAATNRNLKELVSKNMFRRDLYFRLNVLPLKIH
                     PLRERAADIFEIFGSLKYDIPCNFILSEEVKEIFKMYRWEGNVRELRNLGEYFCYLGK
                     DIIEICDLPEYILDTIDSNYSRTVCNKVSDNIKKYQFNIGKDKNIMKYDYNFKRSLDE
                     YIFILDNLKKAYDLKERIGRKSLCKIALEENRFLTEQQIRNMLLELQDFGLVDILVGR
                     GGSIITSKGVEFLKNINRSNKLNS"
     gene            68562..68963
                     /locus_tag="PC466_000466"
     CDS             68562..68963
                     /locus_tag="PC466_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2767896.1"
                     /translation="MKKCLYCNRDIKSPNNKLAIKYDDNMNIYPCRAECKEKIEEYIA
                     KKPTYKFINILEVLLGVGGIFCFLSKWTIAAQVVLGIDALVIFLFPLAGFKMNGKLSM
                     EQTKNQSRSIAISILAFIVIITVLYFKQVGK"
     gene            69006..69299
                     /locus_tag="PC466_000467"
     CDS             69006..69299
                     /locus_tag="PC466_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HDF2767897.1"
                     /translation="MEERKLAPNNEREALIKRLKRIEGQVKGIQKMVEQERYCVDILV
                     QISAIRSAINRVGTIILENHIKGCVAESIKHDDADKTEEMIKELMDTINKFTK"
     gene            69314..69754
                     /locus_tag="PC466_000468"
     CDS             69314..69754
                     /locus_tag="PC466_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SoxR reducing system RseC family protein"
                     /protein_id="HDF2767898.1"
                     /translation="MNQQGFIMEIVDDRTAKLKMQRHSACAACGKCATTNSAESKEIL
                     VEVDNTIGAKVGDHVEVSMDNMNVLKAAVMAYIIPLIALLVGTIGTYYILGAIGMTTG
                     VEAISGLVGICLTIICYLYLKKNDKKFRDSREFIPVITRILIDL"
     gene            complement(69846..70319)
                     /locus_tag="PC466_000469"
     CDS             complement(69846..70319)
                     /locus_tag="PC466_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HDF2767899.1"
                     /translation="MTDMSMILHFLFSGVATAGFAVFFNAPLYLLLPAGVTGGIGWIV
                     YVYLFNFTTNAVFAGFIAAALVSACSETLARKLKQPAIVFVIPGILPLIPGIGLYNTM
                     LSLIQKNYSLAMSKGTDALFLSAAIALGVLVVTSFVRTLNLLKIRKNFIPYRKSK"
     gene            complement(70319..71107)
                     /locus_tag="PC466_000470"
     CDS             complement(70319..71107)
                     /locus_tag="PC466_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HDF2767900.1"
                     /translation="MNQNEELEYKKNILKLALFVGELMIKNGAETSRVEDSVLRICRS
                     RGFYHVNIFTTPTVIIISDEKFDGFSFMKTIQSRGINLNKISLLNSFSREFVSDKEYD
                     IDNAIARLYEIQDVKPYPLWLFYSCTGIASACFACLLGGNYVLNFILTFIIAIFAAIT
                     YDKTMKISAISAFSCLVSSFLIALSGVLLVEIGILDDPKMLIVGAIMPLLPGVAFIKA
                     IRDLISGNLISGISRAFDAAMIIIAIASGVGFVLDTWYRIGGPF"
     gene            71435..72679
                     /locus_tag="PC466_000471"
     CDS             71435..72679
                     /locus_tag="PC466_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HDF2767901.1"
                     /translation="MFENLKKADPEIYESMKRELKRQQRNIELIASENIVSVPVMETM
                     GSHLTNKYAEGYSGKRYYGGCEYIDEVETLAIDRIKKIFGAEHANVQPHSGANANIGV
                     YFAMLKPGDVVMGMNLSQGGHLTHGAPVNISGQYYKFYEYGIDKDSGLIDFDEVRKIA
                     HEVKPKMIVAGASAYPREIDFKKFREIADEVGALLMVDMAHIAGLVAAGIHQNPCEVA
                     DFVTTTTHKTLRGPRGGVILCKEKYAKDIDKAIFPGIQGGPLEHIIASKAVCFKEALS
                     DEFKEYQVQVAKNAKALAEELIKRDFKLISGGTDNHLILLDLINKNITGKAAEKRLDD
                     AYITANKNTIPFDPNGALVTSGIRLGTPAVTTRGMKEEDMAIIAEAIDLCLTYDEESK
                     ARTLVVGLTEKYPLYEEYNIMD"
     gene            73002..74099
                     /locus_tag="PC466_000472"
     CDS             73002..74099
                     /locus_tag="PC466_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-diphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HDF2767902.1"
                     /translation="MKVLILTGKFGMGHYSASNSLSEDIKAKFDNSEITIKDIFEYIM
                     PNYSDKMYKTFSILVNRGSSLYNLFYKCAENGKKDIKFTFSDYFLNKLDTLLHEVQPT
                     VVISTFPFCSQLVSRYKEKYNSNLPLITCITDISSHSEWISKNTDCYLVASKSTKEEL
                     VFKGIDESKIKVNGIPVKKEFKRIEHVNHSTKKNILIMGGGLGLLPKSEQFYKELNSL
                     EGVKTTVITGNNKKMYYKLYGRYENIEVVGYTNEVYKYMKDSDLIISKPGGITLFETI
                     YSELPILAFNPFLQQEIDNASFILNNEIGRILGKNKKYYVDEIKDLIYDDATLKEMSS
                     NMKELKKQFDNNTLENILFSLDEQGACRECM"
     gene            74090..74788
                     /locus_tag="PC466_000473"
     CDS             74090..74788
                     /locus_tag="PC466_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HDF2767903.1"
                     /translation="MYVVGLIIVVALIFLVHSIIPTYYNKLLNKEVLKNMAGENEIAL
                     TFDDGPDKRYTEKLLDVLKENDIQAMFFVVAKNAEKEPEIIKRMLRENHIVGLHSLEH
                     RNAWLYSYSYVKKDFIESTNIMKNLGVDVNYYRPPWGHTNIFSNSFVKKYNLKMTLWD
                     VMAEDWEKDSTVDIIINKLMSRTKENSIICLHDAGENSGGAVGAPERTIEALKIAIPK
                     LKASGLKFVTPERM"
     gene            74791..75855
                     /locus_tag="PC466_000474"
     CDS             74791..75855
                     /locus_tag="PC466_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HDF2767904.1"
                     /translation="MISKTEKKNKCLGSVAFLVLLMGITGYFVFRGQSVESLIKSLKG
                     ASPMFILIGFAMMFIYVACEGINIYLGMKALNQKTTLLKCMGYAFIGFYFSSITPSAS
                     GGQPAQVYYMKKDDINISYSSLILLVIVVIHQVVILAYSGIMFIMEREFILNNVSGMN
                     ILLIYGVITNVALVIGVIAIIFSKKLVNNFIISITNLLGKLRIIKDVESSRKVIISQI
                     EEYVKGAQYIKQNPKLVVQILVITIVQITAMFLVPFFVYKAFHLSTYTVFEILAIQSL
                     LNIAVSSLPLPGAVGASENSFMTLFKIFFPGHLLVPAMLLSRGISFYAFVAISGLICI
                     VVHVKSSEKVKAVKKVAYVR"
     gene            76038..76742
                     /locus_tag="PC466_000475"
     CDS             76038..76742
                     /locus_tag="PC466_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2767905.1"
                     /translation="MNKEIPKKILVADDNPEIREIVEILLTGEGYEVIMATNGEEAVN
                     LVDSTIDLIILDVVMPVKTGFVACNEIREKTTAPILFLTAKTQDSDKVIGFSAGGDDY
                     LSKPFSYSELISRVKSLLRRYYIYQGKEKEREPNILKTKELCVNLDTQDVTLNGEPVF
                     LTTIEYSILILMLKNRKKVFSSENLYETIWDEQYFYTANNTIMVHIRNLRKKLEKDQK
                     NPQYIKTAWGKGYYID"
     gene            76735..78057
                     /locus_tag="PC466_000476"
     CDS             76735..78057
                     /locus_tag="PC466_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2767906.1"
                     /translation="MINKIKPSKLGVILLIYVVISAAVAFILNIPFYSAVESIVKDVS
                     EGKVYFKREVNQLMDNFQTYVNNNGIRADDGDDIAKWNSDNWFVSMKIYKGNKVFYDT
                     LYYPNEVPDKSEENEFYSSPMARNYEIQFSDIKANIVVVALFRFRFQNFIEAISITFM
                     ALTFIITFLLLFSRKIKYLRKIEMGIKIVESGSLKYRIPVKGNDELSSLASSINEMSH
                     TLENQLIKEREMKNKNKDIVTSISHDVRTPLTSVICYLDLIKDHKYNSPEQLEQYIKN
                     VRSKAYQIKDLTDDLFTHFVNSGEEVSKGYEKINANEFIFQLLLDSSYTLEEKGFHIT
                     IENELYNQYHIYVDVTQFRRIFDNLCSNIIKYARKDKPIVFLIKVEDSKLLIIQKNRV
                     SNFSKNVESFGIGIKNCEKIVAYHNGSINVNSDDKEFAIEISIPAKES"
     gene            78244..79617
                     /locus_tag="PC466_000477"
     CDS             78244..79617
                     /locus_tag="PC466_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2767907.1"
                     /translation="MVLTGAHYIYILFMVIILITMIMKKDTIVPCILGVFFMGLFFEK
                     NIFGAITAVFNSFIISLNELGPIILIIAIMVALSKALEANNAIQYMVRPFSRVIKNSN
                     TAFFVTGFVMLVLSWFFWPTPAVALVGAVFLPVAMRAGLPAIGVAVALNLFGHGLALS
                     TDFVIQGAPSITAGAAGVAVSYVINDGMILFWVMGIVTISMAFYTLKRDINKGMFREE
                     LKGFESEEVEEFNGKSKIATILVALGFLADIIVMYIFDLKGGDASALLGGTAVFLIII
                     INVINFGKDSLENVCENIIDGFVFGIKIFGAIIPIAAFFYMGEVAPLTGVFGKVLAPG
                     SQGLLSDIGIALSQTIPLNKFAVSGIETVVGAITGLDGSGFSGISLVGSLASVFGTAI
                     NASVGALAALGQISGIWVGGGCLVPWGLISAAAICGVSPIELAKRNFVPVITGLVVTT
                     IVAMFII"
     gene            complement(79990..80928)
                     /gene="pdaA"
                     /locus_tag="PC466_000478"
     CDS             complement(79990..80928)
                     /gene="pdaA"
                     /locus_tag="PC466_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="delta-lactam-biosynthetic de-N-acetylase"
                     /protein_id="HDF2767908.1"
                     /translation="MFRKVLHYLTLLSISIFFIVGCSNSQNNQNENQNKETQLQEDKE
                     KIDGGKDTSNVIVSDGTDKPSKATTNNDNNKLDVSSLDNTTLDWFYIPNNKHKTPEVN
                     TDIEFKFSDYDALYNGPTKDGQKTLYLTFDEGYENGYTTKILDTLKQNQVKAVFFVTA
                     PYIKENKDLVKRMVSEGHIVGNHSKTHPSMPTKTSNLKNFNDELYDVEKLYKDVTGKD
                     MVKFFRPPMGKYSEKSLAMTKNLGYKTVFWSFAYRDWDTDKQPSHEEATQKIMDNLHD
                     GSILLLHAVSKTSTEILNDFISNARKLGYEFELLEY"
BASE COUNT        31836 a         8877 c        13990 g        26464 t
ORIGIN      
        1 aatttcaaat aatgttgtag attctaaact tacgaatagt aggattaaat caatagatat
       61 aataagaggg ctatcaatag ccctcatgat agtctgcaat aatcctggga cttggatgag
      121 aatgtatcct caattaagac atgctgtatg gcatggtgta acacttgcgg attttgcatt
      181 tccttttttt gttatatctt taggtgttac aattccaata tcaataaata gtaaactaaa
      241 aaataataaa tccacactga gtataatact tagtatattc aagagaagta tcttattgat
      301 attatttgga tttttcttaa attacctagg aaatcctgat ttaaattctg tgagaatact
      361 tggagtactt caacgtatgg gattagtcta ttttgtgact agtttagtat atttactact
      421 aaaaaaatta aatgttggaa gtactgctac aataattact tttctatgta tagctacatt
      481 tataatagtt gggtactaca tattagcaaa accttatgga tttgagctag aaggttctct
      541 tgcacagtta gtggatttac atttcttcaa gggacatttg tacaagccag aatttgaacc
      601 agatggtttt ttaactagta tagtagcaat ttcttcaggt atgttgggat gcactatggg
      661 atgtgtactt ttaaaagaaa acataggaga atataaaaaa ttctttaaaa tactggttat
      721 gagcataatc ctgctaatag gtgcttttat ctttaatcag tattttccat ttaataaaag
      781 attatggtct agctcatttg tacttttaat ggctggcagt tatggtatgt tactgtcaat
      841 attttatttt atatgtgaca tcaaaaataa aagtaaaata tttaccccaa taatagcact
      901 tggaagtagc cctattttta catatatgtg ccttgagata ttgagtcatg ttttttggaa
      961 tgttccaaaa cttacgaaca aagtcgatta tccaactacc ttggtagagt ggactacata
     1021 tgaacttata acaccttggg caggtacaac ttgggattct cttatatttt ctttattgta
     1081 tgtcctattc tgggttatag taatgtctat aatgtacaag aaaaaaatat ttattaaaat
     1141 ttagtgcaat atttttagat gataaagtct ttgatttgtt caaatatacg gaaactatca
     1201 aatataatca aaatttctcc tcgataaaat ttaaaaacca tgccataaaa gattacaaaa
     1261 agtttacaat ttgtaatttt ttgtgctata atgaaaaaag atttacataa tattgaattt
     1321 atgtaatata aaacaagctt aagatgtatt aaaaaagatt taaagattta aagaaccaaa
     1381 aaattagggg ggatatgatg aaaaaaacaa caaaattatt ggcaacagga atgttgtctg
     1441 tagcaatggt ggcaccaaac gtagctttag cggctgaaaa tactactgca aatacagaat
     1501 ctaattcaga tattaatata aatttacaaa gaaaaagtgt agtgttagga agtaaatcta
     1561 atgcaagtgt aaaatttaaa gaaaaattaa atgctgattc aataacatta aattttatgt
     1621 gttatgatat gccacttgaa gctactttaa attacaatga aaagacagat tcatatgaag
     1681 gtgtaataaa ctataacaaa gacccagaat acttaaatgt atgggaactt caaagcataa
     1741 aaataaatgg taaagatgaa cagaaagttt taaacaaaga agacttagag tctatgggat
     1801 taaatcttaa ggattatgat gttacacaag agtttataat aagtgatgca aattcaacaa
     1861 aagcagtaaa tgaatatatg agaaaaactt ctgcgccagt aaaaaaactt gctggagcta
     1921 ctagatttga aactgctgtt gagataagta aacaaggttg gaaagatggg tctagtaagg
     1981 ttgtaatagt taatggagaa ttagcagcag atggaattac agctactcca cttgcatcta
     2041 catatgatgc accaatatta cttgcaaata aagatgatat accagaaagt acaaaagcag
     2101 aattaaaacg tctaaatcca agtgatgtaa taattatagg tgatgatggt tcagtttcac
     2161 aaaaggcagt atctcaaatt aaatctgctg taaatgtaaa tgtaactcgt attggtggag
     2221 ttgatagaca tgaaacatct ttacttatag caaaagaaat agataagtat catgatgtta
     2281 ataaaatata catagcaaat ggatatgctg gtgaatatga tgctcttaat atttcatcaa
     2341 aagctggtga agaccaacaa cctataatat tagctaataa agactctgta ccacaaggta
     2401 catataattg gttatcttca caaggtttag aagaagctta ttacataggt ggtagtcaaa
     2461 gtttatcatc aaaaattata gaccaaatat ctaaaatagc aaaaaatggt acttcaaaaa
     2521 atagagtttc tggagcagat agacatgaaa caaatgcaaa tgtaattaag actttctatc
     2581 cagataaaga gttgagtgca atgttagttg caaaatctga cataatagtt gactcaataa
     2641 cagcaggacc tttagcagct aaattaaaag ctccaatact tataactcca aagacttatg
     2701 tttctgcata ccatagcaca aacttatcag aaaaaacagc aggaacagta tatcaaattg
     2761 gtgatgggat gaaagatagt gttataaatt ctatagcatc tagtttatca aaacacaatg
     2821 caccaacaga accagataat tcgggttcag cagcaggaaa aactgtagtg atagacccag
     2881 gtcatggggg ttctgattca ggggcaacaa gtggattaaa tggtggagca caagaaaaga
     2941 aatatactct taatacagca ttagcaacta ctgaatattt acgttcaaaa ggtataaatg
     3001 ttgttatgac tagagataca gacaaaacaa tggctttagg agaaagaaca gcattatcaa
     3061 acactataaa gccagattta tttacaagta tacattacaa tgcgtctaat ggagctggta
     3121 atggtgtgga aatttattac aaagtaaaag ataaaaatgg tggaacaact aagactgcag
     3181 catcaaatat cttaaaaaga atactagaaa aatttaacat gaaaaataga ggaatcaaga
     3241 caagaacact tgataatgga aaagattacc tatatgtgtt aagaaataac aattatccag
     3301 caatacttgt tgaatgtgca tttattgaca ataagagcga tatggataag ttaaatactg
     3361 cagaaaaagt aaaaacaatg ggaactcaaa ttggaatagg aatagaagat acagtaaaat
     3421 aaaataaaaa atattaaagc aaaacatatc atctcctgtt ataatgtaaa atataacaag
     3481 agatgatata tttttgtaaa gaatcaaatt gtttacaatg atgtttcttg tattgataat
     3541 ctgctcatta ttgagtataa tatagaaata agtcaaaaat aagatagaaa taagttgaaa
     3601 ttaagaatta aaaaaatttt tattccaata tggaggtaac tatgtctgga tatactaatg
     3661 atgagtgtga aatacctaaa attaaaagct atccaggggc agataaagaa attgcaagtg
     3721 agattgacta tagcatagta aaaggaacgg ttttattcga cttgtaccaa agaattatgg
     3781 atttagtttt atctataata ggacttgtga taggtttacc tttaatagca atatttggaa
     3841 ttcttattaa aatagaggac aaaggaccaa taacttataa gcaagaaaga ctaggaaaat
     3901 gcgggagaag attctatata tataaattaa gatctatgag aacagacgca gaaaaatttg
     3961 gcgcacaatg ggctgaaaaa gatgatccta gaataactaa ggttggaaag tttattagga
     4021 aaactagaat tgatgagatt ccacagctgt ttaatatatt aaagggggat atgggcttaa
     4081 taggccctag accagagaga ccgaacttta ctgttcaatt caatgaggaa atacctggat
     4141 ttatcaacag gctcgctata aaacctgggc ttacaggttg ggcacaagta aatggtggat
     4201 acgaaatcac tcctgaagaa aaacttaaag aagatattta ctatataaaa aataggagta
     4261 tattacttga ctttaagata ctctttaaaa ctgttaaagt agtattgaca ggagacggag
     4321 ctagataatt ttaaaatatt agattactaa tcaatgaaaa agctctttaa aaagagcttt
     4381 tttattgtca aaaaatacaa aaaagaaaag gaatgagaac ttatgattaa aaaaatttct
     4441 actatattat cgttagtttt gttaatctct atttctagca caatagaggt atttgcagat
     4501 gcaaatccca aaagagaatt gatagaaggg agtataccag agatttcgac agaattaaat
     4561 aaaagagcat ttaaggattc taaagaagta attcttgtaa atgaagagtc aattgtagat
     4621 agtataagtg caacaccttt agcatatgca aaaaatgctc caatagttgt aactaagagt
     4681 aaaaatcttg gtagagtaac aagaaattat ctaaaagaac taggtccaga gaaggttacg
     4741 atagtaggtg gtttaaaggc agtatctaaa gatgctgaac gtaatataga aaaaatggga
     4801 ataaaagtag aaagaataag aggaaaagac agatatgata catctttaaa gatagctaga
     4861 gaaatgtata gaacagtagg atttgatgaa gcatttttac ttagctcaac aacaggatta
     4921 gagaatgcca tatctgtata ttcttatgcc gctaaaagtg gaatgccaat aatatgggct
     4981 aaagatgaag ggtttgagga acaaattgat ttcttaaaag gtaagaatct taaaaaaata
     5041 tatgcattag gtgattcaaa agaatttatt gcagagattg attctaactt gaaaaatata
     5101 gaaggaataa agcaaataaa taagtcaagt acaaatgttg atttaataaa gaagttttat
     5161 gatgaaaaag atataaagaa aatctatact gctaaattag actttggtag cagatctgat
     5221 gtaaacgaat atatttcttt gggagtagta tcagcaaaag aaaatatgcc aatactgatt
     5281 tgtagtgata acttaagtcg tgcacaagat aaattcttga aagatagcaa tataaatgat
     5341 gtagttgaag ttgggtatac agtaggtgat tatagtctat ttaagagcat atttaatcta
     5401 acattcttat cttgtatagt attaatacta ttattactat tgattacatt tagggcactt
     5461 agatatgagt cgaaatagtt tttaatttat aaggaagctt ttcataggtt aaatttactt
     5521 aattagaata atgtttataa gcagttttaa aagttctact tttagagttt aaattagata
     5581 aggagaaaga agatgtcaaa aacagctaaa gcagcattgt ggattatggc agccactatg
     5641 ttttcaaaag tattaggttt ccttagagaa cttgtacttg caaatttcta tgggacaggt
     5701 atgtatgcag acgtatttgt attaacatta aatatacctg gtttaatcat agcagtcata
     5761 ggctctgcag ttgctacaac ttatatacct atgtactttg agacaaagaa aagactcgga
     5821 gatgaaggtg ccttaaaatt tactaataat gttttaaata tatgctatat aatggctata
     5881 gtaatagcta ttattgggct tttatttaca gagcaatttg ttacagtatt tgcagcagga
     5941 tttagaaacg accctgctaa gttccaagca gcaatattat ttactaaaat aatgatttca
     6001 ggagttttat tcctaagtgg aagtaagata tttagttcgt ttttacaggt gaatgacagt
     6061 tttgtaattc ctgggcttat aggaatccca tataatatta taataatagc agcaatagca
     6121 ctaagtgcag gtaaaaacgt atggatacta ccagcaggag cactattggc tatggcgagt
     6181 caactattat ttcaactgcc atttgcattt aagaagtcct acaagtataa gccatatata
     6241 aacttaaagg atgagtctat aaaagaatta gtaaacctag tattgcctat gttggtagga
     6301 gtagctgttg gacagttaaa tatatttgtt gacagattat tggcaactac tttgggtgat
     6361 ggaaagttgt ctgctcttaa ctatgcaaat aggctaaatg agtttgttat ggcattattt
     6421 gttacatcta taataacagt tatatatcct aagctagcaa aaatgtctgg taaagatgat
     6481 aaagaaggat ttataagtac tattgtaaaa tcttcaaatt gtattatatt ggtggtgctt
     6541 cctatatcta taggagctat tatattagca gagcctcttg ttaggatatt atttcaaagg
     6601 ggtaaatttg atgcgttatc aacagatctt acatctatag cgcttagatt atattcacta
     6661 ggtttattgg cttgtggagt aagagatgtc ttatataggg cattttactc tctttcagat
     6721 acaaaaacgc caatgataaa tggaagtata gctttaataa taaatatagt tcttaattta
     6781 atattgataa gaccattagg tcatgcaggt attgctatat caactagtac atccaatata
     6841 attacagtta tattgttatt tatatctctt aaaaagaaaa atggatattt tggaggggat
     6901 aaaattataa agactggtct aaaaagtttg gtagcatctg gtgtgatggc agtagctact
     6961 ttattgatat ataataatct atatgcattt atgggttcag gaacaattaa agaaattata
     7021 tcagttggag ctggagtatt aggtggagct tctgtatata ctgtattgat agttttattt
     7081 aaggtagaag agatggactt agcttttgaa tttttaagaa aaggaaaaca aaaactactt
     7141 agaagaagat aattaccttg aaattttaaa ttagagtcag aaaggatgaa aatatggatt
     7201 ataagaataa ttatgagatg tggttaaatt ctccttattt tgatgagcaa acaaaaaatg
     7261 agctattaag cataaaagat gatgaaaaag aaatacaaga tagattctat aagaatttag
     7321 agtttggaac aggtggttta agaggtataa taggagcggg aactaataga atcaatattt
     7381 atactgttag acgtgcgaca ctgggcgttt taaattatat catgaagact caaggagaag
     7441 aaggtaaaca aaagggaata gttatagcac atgatagtag atacatgtct agggagtttt
     7501 gtatagaagt agcaaagact ttaagtgctt atggtgtaaa ggcttatatt tttgaagaat
     7561 taaagcctac accagaactt tcttttgctg ttagatattt aaagtgtgct atgggaatag
     7621 taataacagc aagtcataat cctaaagaat acaatggata taaagtatat gactcagatg
     7681 gtggtcaaat ctgtatagat atggcaaatg atataatagc agaagttaat aagattgatg
     7741 attacagcac tattaaaagt atagattttg aagaagcttt atctaaaaat ttaataacta
     7801 tattagataa tgaagtagat gatgagttta taaaagctgt taagaagcaa gttttaagac
     7861 aaaatataat agatgaatac gggaaaaaat taaaaataat atatacacct attcatggta
     7921 caggaaataa accagtaaga aaagtcttaa atgaatgtgg ttttgaaaat gtaatggtag
     7981 ttaaggagca agaattacca gattctaatt tttcaacagt aaagtatcct aatcctgaag
     8041 aaaagtcagt gtttaatata gctattgaaa tggcaaagaa taatgacact gatttgataa
     8101 taggaacaga ccctgattgt gatagagtag gtatcgttgt aaaagattca agtggtgaat
     8161 atgtagtctt aaatggaaat caagtcggtt cacttttagt tagatatata ttagagagtt
     8221 tagttgaaga aaataaactt cctaaaaaca atcctacaat aataaaaact atagttacat
     8281 cagaactagg tgcaaaaata gcaaaggctt ataatgtaga ttgtttaaat actttaacag
     8341 gatttaaatt tataggagaa aaaataaaag cgtttgaaga aagcaatgat agaagtttta
     8401 taatgggata tgaggaaagc tatggttact taattggaac tcatgctaga gataaagatg
     8461 gtgttgtatc ttcacttatg atatgtgaaa tggcagcata ctattcttca aaaggtatga
     8521 acttgtatga agctttgata gatacatata ataaatttgg atactacaaa gaggacttaa
     8581 agtcagtaac tttaaaaggt atagatggaa taaaaaaaat aaaagagatg atgctttact
     8641 ttagaagtgt taaaatagat aatgtggctg atgtaaaagt agataaaatt ttagactata
     8701 aagatggtgt tgatgattta cctaagtcag atgtacttaa atttttactt gaagatggct
     8761 cttggatagc tataagacct tcaggtacag aacctaaaat taaattttac tttggagcaa
     8821 attcagacaa tcaagaagat gtagaattta agttgaacaa tttaatatct tatatattaa
     8881 atgtagtgga ttctatataa aaagctaagg ggagataaat aatgaaagta tacaatgtca
     8941 taatggctgg aggaggagga actcgtttct ggccacttag tagacaagaa gtacctaaac
     9001 agcttataaa tttaagtgga gaagatgctt taataaacga aactataaac agaatagatt
     9061 ctctagcaaa aaaagatgat ttatttatag taaccaatga gaagcaattg gaagctttaa
     9121 aggatatagt aaaagataaa tgtttggata gtaatatatt gccagagcca tgtgccagaa
     9181 atacagcagc agctataggc tttgcagcat ttaacataat gaaaaaatat ggtgatggtg
     9241 ttatgtgtgt atatccagct gaccattata taaaagatga aaaagaattt aaatctattt
     9301 tggaaaaagc tatctatata gcagaaaata atgataaact agtaactatt gggataactc
     9361 ctacatttcc atcaacagga tatggataca taaattttaa tagagaaaat acgatagaag
     9421 atgttgcata tgaggtagtg gagtttgtag aaaaaccaaa ctatgaaatt gctaaagaat
     9481 atgtaaactc taaaaagtat gtatggaata gtggaatgtt cgtatggaag gtatctaaaa
     9541 tattagaaga ttttaagaga tacttgccaa aagtatatga aaaattagaa tatataagta
     9601 aatacttagg aacaaaagaa gaaatggaaa aaataaaaga aatataccca actatacaat
     9661 caatctctat agattatggt attatggaaa gaagtaatga tgttatagta gttcctggtg
     9721 attttggatg gaatgatgtt ggttcttggg attctctagg tgcaatatat ccaactgatg
     9781 atgaaggtaa catcaaaaga ggtgaaaata ttactataga tactaaaaat tcaattatat
     9841 attcagatga caaattaata tcaacaatag gtattagtga tttgatagta gtatctacga
     9901 atgatgcagt tatggtttgt agaaaagata aagctcaaga tgtcaaaaaa atagtagaac
     9961 agttaaaaga agaagataga caagaatata tgtaggaggt gttcatttga ttcctaaaaa
    10021 aatacattat gtatggtttg gtggtccaaa aggaaatata gaaaatatat gtataaattc
    10081 ttggaaagaa aagcttccag aatatgagat agtagagtgg aatgaaaaaa actttgatat
    10141 agagaaagaa ataaaaggaa ataagttttt ggaagaatgt tataaaagaa aactttgggc
    10201 attcatatct gattatacaa gaataaaagt actctatgaa caaggtggag tttatatgga
    10261 tacagatatg caaatattaa aggatataac tcctctttta gaaaataata ggctaatctg
    10321 tgggtatgaa gatgatagag agtatataaa tggtgctata ataggtgtag aaaaaggaca
    10381 tcctttttta aaagacttat tggagtatta tgaaaaagaa gtacttactt cttcattgtt
    10441 tacaatacca aaaataatga ctcatcttat ggaaaagaat tataagaaga ttgacccaaa
    10501 taattatgaa gaaggaatac gtgtttacga caaagaatat ttttatcctt ttggatttaa
    10561 agaagacttt acaccagaat gtataacaga aaacactttt gggatacatt ggtggggaaa
    10621 aagttgggct aaaaagagaa attatttctt agaaagcaaa cacttaacag gtgtaaataa
    10681 gatatggaag tgttgtaaaa tatttgcaag taatacttta cgaagctaaa agggagaaag
    10741 taaaatgaag actttaaatg atgatagaaa tattatgatt agaaaatatc tttatatatt
    10801 tgttttgttt atcatattac ttagaaagta tatgatatca tttattgacc caaatataga
    10861 tatagggatg attaaatcag cgttatttta ttcttcaata ggaatactaa tgctactttt
    10921 tttatttgat aagagaaaaa gtataacaga aatggtacta gttggagttt gtgtcttact
    10981 ttatttatta aatagggaag gagctatatt attaatcgtt ttattagctg tatcagctaa
    11041 gcaaatagat gataaattta tagttaaaaa ttatttaata atatcggcat gttttttaat
    11101 ggtagctata ttattattta atttatttcc ttcattaata tttaatcagg aagtccacta
    11161 tagatatata gaaaaaatag atatgcttgt tacaagaatg gattttggac ttggtaatcc
    11221 aaatagtgta ttttatcata tggttactat atatgcagca tatatattct taagatataa
    11281 agattataat aaatgggata gaataatttt atttggttct gcattttttg tttatcaaac
    11341 cacatatagt agaactggat ttttcactat attagcagga ttaatatttg tagaaataat
    11401 aagatggata gatataaaaa aaataaaagg actgccaatg ctcctaaaga cattaccaat
    11461 aatacttact ctatttagtg taattattgg tacaatattt gataaaagca ctttattaaa
    11521 tagattatta gcaagtagac ctaagttctg gcatgtatac ttggctgaaa aggggaattt
    11581 tctaaaacct tttggaaatt catatagtcc tgctataaaa gcaactaatc cattagatag
    11641 ttcttatgta tatataatta gtgtactagg agtagttgct tgtatattat ttatgtattt
    11701 gatgtataaa ggaatagaaa gctttataga aaaagataaa aaagcatatt tagtagcttt
    11761 atttatattt ttactatact cttttgcaga aaatttatta ttagaagctt catttagttt
    11821 tgcagtagta ttactaataa aagaagtgat attaaatgat aaaagggaaa tagatttgtg
    11881 gaagatgaaa agtaggaggt agtaatgtta atatcattaa taatgccaac attaaataga
    11941 tatgatgata tatacttact tatggatagc ttagaaaatc aaacttacaa aaactttgaa
    12001 cttatagtag tagaccaaaa tgataatagc aaagttaaag aaatagttga taaatacatt
    12061 gataagttag atataaagta tataaaaagc tctaaaaaag gattgagtta taacagaaat
    12121 gtaggcatag ataatgctgt agggcaaatt ataggtttcc ctgatgatga ttgtgtctac
    12181 gaaaatgata cattagaaaa agttataaat ttctttaata aaaatgaaga ttataaaata
    12241 tacagttgca aaactatgga ttcaaataaa gttgatgcat ttaagaaaat gtatgatgga
    12301 acttgtgata tcacaagttc caacgttttg gatactataa catccataac tttttttatt
    12361 gattttgaag gtaaagatta tacaagattt gatgaaaaat tgggtgttgg tggagagttt
    12421 ggtgctggtg aagagataga ttatgtttta aacttattga gtttaggttt taaaggaaaa
    12481 tactttggaa atgatataat ttaccatcct gcaaaaaaac attctaaatc taaagaaaag
    12541 tatcaaaaag attataatta tggaagaggc tttggagcgc tttgcaaaaa ggaaatagtc
    12601 tatagaaaaa attatacgtt tgcaaaagtt atggtatcaa aacttgtaag aaatataggg
    12661 ggtcttatat tgagttccaa tagagattat catagtgcca ctataaaagg aagaattaat
    12721 ggatttagac agtacaagtt ataatgagga tggtgtttat ggacaaggtt aaatttttaa
    12781 taaatatgct tttggctttt tttatatatc catttaataa gcataagttt aatggtagag
    12841 atatctggct tataggtgga cattcagggg atatatacaa tgataattca aagttttttt
    12901 atgagtatat gctaaaagaa cataatgatg tagaaactta ttgggtagta aataaagaca
    12961 gtaaagtatt tgataaaatt ccaggcaaaa aattaataag aggaagtgta gaaaactatc
    13021 tgtattatta caattcaaaa gctatagtat tttcacatgc accatcagca gatatagcac
    13081 catacaattt tgctgtacct gttcttaatt attttcataa aaaaacgata aaagtgtttt
    13141 taaatcatgg gactataagc tttaaaaaaa gaaaacctat gaacaaaaag ttcaaaaata
    13201 ttatagataa cctatataaa agctataata tagttacagc aagttctgaa tttgaaagaa
    13261 atgttatggt aaatgattgg ggaatgttag atgactcagt ttatataatt gggaatgcaa
    13321 gatatgacaa tttaccaaca aatgaagttg cacaaactcg agatatatta tatactccta
    13381 catggagaga ttggataaaa tttagttcag gaaaatttac ggatacagat tattttaaaa
    13441 atataatgaa ttttttaaat gatgacaaat taaataaaat attagatgag aaagatataa
    13501 atgtaaaaat ttatatgcat catcttatgc atgagtttat agatgatata aaagaaaata
    13561 taacaggaaa acgaattgtg tttttagata aaggggtaac tctagcaaat gaaatcagaa
    13621 aatcagctgc aaatataact gattattcaa gtgtagccat agactttttg tatatgaata
    13681 gacctatctt gttttaccaa ttcgatttgg atgaatatat ggaaaaagtt gattcatata
    13741 tagatttaaa aagtgaaatg tttgggtctt tggcttataa taatgatgaa gccgtgaata
    13801 aacttattga tattattgaa aataattttg aggttatgga taaccaaaaa aatgaaagaa
    13861 ataagttttt cagatataat gataataaga actgcaagag gatatatgat tgtgtattaa
    13921 gtaaaattaa ataaatattt tataaatgat gaggaaggta atatgaagaa gaatttagta
    13981 tctataatta ctcccatgta taattctgaa aaatttattg aagcaaccat aaaatcagta
    14041 ttaaaccaaa cttatcaaga atgggaaatg ttaattattg atgattgctc aacagataat
    14101 agtcctaata tagtcaaatc ttatatgcaa caggatagta gaataaaatg tataaagact
    14161 gagactaata agggtgtctc taatgctaga aatttagcac taagtaaggc aacaggacaa
    14221 tttatagctt ttttagatag tgatgaccaa tggaatagca gtaagttaga aaaacaagta
    14281 aattttatgt tagaaaatga ctatgtaatt tcatttactt catatgaact gatggatgaa
    14341 aatgataaaa aattaaacaa agtaataaaa gttccaccta atgtagatta taaaagatta
    14401 ttaaaaggaa atatcttagg atgtcttact gttgtgattg ataagtctaa attggatttt
    14461 gaaataagaa tgagtggtgt aagacatgaa gactatgttt tatggttatc gatattgaaa
    14521 aaagggcata ttgctcatgg aataaatgaa gttctagcat tatatagaaa atctagcaat
    14581 tccctaagtg gtaataaaat aaaagctgct atgtggactt ggaatatata tagaaatata
    14641 gaaaaaatac ctttatacaa agctatatac tactttatta attatggaat aaacggaatc
    14701 aaaaaaagtt agacagagag gaagatttaa ttaatgtata aatataaatt tactgtattt
    14761 actccgacgt ataacagagc tcatttactt gaaaatttgt acaatgattt aaaagctcaa
    14821 acttatgatt tcaatgattt tgaatggttg attgttgatg atggaagtag cgacagtact
    14881 aaagagttag ttgaaaaatt tatatcagaa aataaattaa atataagata tatatacaaa
    14941 gaaaatggag gaaaacatac tgcaataaat ctaggtgtaa aaaatgcaga tggagagcta
    15001 tttttcattg tagatagtga tgatggttta attaaagatt ctcttgaaat tgctaatgat
    15061 gagtgggatt ctttagagaa taaagaagga tttagtggag ttgttggact ttgtgtatat
    15121 ccaagtggag atttgatagg gacagaaatg cctgaagata agaaaatatg tcactttgca
    15181 gacctatatt ttaagtatgg cgttaaggga gataaaagca tagtatttgt aactgatgag
    15241 cttataaaat ttccttttcc agaaagaaaa gaagtgagat ttttaccaga aagtgtagta
    15301 tggaatgaaa tgtctaaata ctataaagtt atatgtgtaa ataaacctat gataataaga
    15361 gattatttgg atgatggttt gactaagaat atattaagta aaaatgcatt aagaggtaga
    15421 gcattagagt ttttatattt aataaatcaa aatacatatc cattaagtag atatccatat
    15481 atgtggataa aaaattacat aaatttagcc agatactcat tgttgtctga tagtcattat
    15541 tttggtgaat taagaaaagt atctgataaa ttgttgtatt tagcattatt cccattagga
    15601 tattacaaat atattggaca aagaaaatta gtatctaagt aaacttgttg gtatagtact
    15661 gctagttgct atataaggag agtaaaaata tgaatgagcc tttagtatcg ataattactc
    15721 ctgtttataa ttcagaagag tttttatcag agacgataaa gtcaatccaa aatcaaactt
    15781 ataaaaattg gcagctttta ttagtggatg attgttctaa ggacaattca agtgaaatta
    15841 taaaaagttt tcgaaaagaa gatgctagaa taaaatatat aaagcttgaa aaaaattctg
    15901 gagctgcagt atctagaaat gttggtatta agaatgcgga aggtcgattt attgcatttg
    15961 tagatagtga tgatttatgg gatagtagaa aattagagat tcagatagaa tatatgttaa
    16021 aagaaaatgt aggtttttct tttacatctt atagatatat gagacaagat gggtcaaaaa
    16081 cgaataaggt tgcaagagct cctaagaaaa ttgactatga aggattactt agaaatacta
    16141 taataggatg ttctacagtg gtcattgata aggagattgt aggagagttc agcatgcctt
    16201 tggtaagaag aggacaagat actgcgacct ggttacagtt acttaaaaag gaaaaatatg
    16261 catatgggat tcaggaggat ttagtgaatt acagattagt tggaaattct atatcaagta
    16321 acaagataaa agcattaaaa cgaacttgga atacttatag aaatgttgaa aatttaagtt
    16381 taccaaaaag tctatatgta ttttgtttct atgtttttaa tgccattaaa aaaagagtat
    16441 aagttttata tacttggagg taaaaaaatg aaaatagcta tagctgggac gggatatgta
    16501 ggtttggtta caggtgtttg tctagcagag gtaggcaatg aaaatgtagt ctgtgttgat
    16561 gtagatgaac aaaaagttaa atcaatgaaa cttggaatag cacctatata tgaagaaggc
    16621 ctagaagaac ttatggttaa aaattacaac agaggaagaa tagattacac tacagactat
    16681 aaaaaagctt atgaagatgt agatgtaata ttaatagctg taggtacacc tgagagaagt
    16741 gatggctcag ccaacctaga ttatataaag gcagttgcaa agcaaatagc tgaaactgtg
    16801 acaaaagata ctctagtagt aataaaatct acagttccaa ttggtacaaa tgaagagata
    16861 gaagattata taaatagaaa cctaaaaaat aatgtaaaag tagagcttgc atctaatcca
    16921 gagtttttat cacaaggaac agcagtaaaa gatactctat atgcttcaag aatcgttata
    16981 ggtgtagaaa gtgaatgggc tagagaaata ttagaagaaa tctataagcc ttttaatcaa
    17041 cctataatag ttacaaatag aaatagtgct gagatgataa aatacgcatc aaataacttc
    17101 ttagctctta aaatatcatt tatgaatgat attgcaaatc tttgtgaaat agcaggagct
    17161 aacatagaag atgtagcttt aggaatgagt tatgatgata gaataggaag taagttttta
    17221 aaggcgggaa tagggtatgg cggttcttgc tttccaaaag acacaaaagc tcttcactgg
    17281 ttatctgaac ataatggtta tgaattaaaa acagtaaaag ctgcaataga agttaatgaa
    17341 agtcaaaaac ttaaattagt tagaaaggca tctaagttag tagagagctt tcaagatatg
    17401 aaagttgctg ttttaggttt gacttttaaa ccagacactg atgatataag agaagcacca
    17461 tctataccaa atataaaata tttgcttgaa agaggggcaa gagttactgt atacgaccca
    17521 attggtgtaa ataatactaa gaaaatattt ggtgactcta tactttatgc tgattctgta
    17581 gatgatgcga tagaagatgc agagatatgt tttataatga cagaatggaa agatgtatta
    17641 aattatgata tacataagta taaggaaaag atgaaaaatc ctttagtcct tgatggaaga
    17701 aattgttata aaattaaaga tatggaagag ttaggaattg agtattattc gataggaagg
    17761 taaatattat gaagactgtt tgttatttag ctgatgggtc aaatcctcat actttaaaat
    17821 ggtgtagttt ttttaaaaat aaaggatatg acattcatgt aatctcttta aatggaggtc
    17881 acatggaagg aataaaaatt tataattttg gttctaatgt agaagaatta aaaaatgaaa
    17941 atatttctaa aaaaacggga tacttaggtt caataaagca gataaagaag ctagtaaatg
    18001 aaataaagcc agatatattg catgcacagt atgcaagtag ttatggattt ataggaagtc
    18061 tacttgggta tcatccatat attatttctg tttggggtac tgatatttat gatttcccta
    18121 ataatggttt tatacaaaaa caaattataa aacataactt tagaaaagca gactatatct
    18181 tttcaaatag tagagatatg gctaaagagg ctaataaata tacagctaaa catgtagatg
    18241 taaccttttt tggagtagat atggataggt ttaagcctat ggaagtagaa aaagaagacg
    18301 cttttgtaat aggaattata aagagtttag aaaaaaaata tggaatagaa tatttaatac
    18361 aagcatttaa gatgcttaaa gatgaatata aagataagaa aataattctt aaaataggtg
    18421 gctctggaag tcagatggac aacctaataa atttagctaa agaattgggt atagaaaatg
    18481 atgttcagtt tttaggaaga atatctccag aaaatgtaag caagactttt aattcttttg
    18541 atgtaactgt atttccttct ttaagagagg gatttggagt ggcagctata gaatcagaag
    18601 catgtgaagt acctgttata gttacaaatg taggaggaca tccagaatct gtatgggaaa
    18661 atgaaactgg cttaattgta gaaccaaaac aaccagaaga aataaaaaat gctataataa
    18721 aactaatgga aaatgatgaa cttagactta atatgggtaa gaaagggcgt caatttgtta
    18781 gagaaaatta tgaggttaat ttaaacttta atgatataga aaaaatttat gattctatat
    18841 ttgataaata taaaaaataa aatgaaaaaa tacagcaaaa gatagatgtt gttggctatg
    18901 cttaggtgcg tagcttttgc tgtttaaagg agggcttcta gttatgcgag aaagtataga
    18961 tttagagaaa gaaagctttt ttaataggct ttttaaaaaa tataaattta gacatttaac
    19021 actattaatt ctagatattt gtagcgtact agtagcgttt cgaatgtctt taagcttgac
    19081 aggtaattta aatgcattta ccactaatga tataataatt tcagtgtgta tatatatagt
    19141 acttcatata gtatcattta gattgtttaa gtgctacaac acattatgga gatatgcagg
    19201 agaagaagaa attatatcta tttttgtggc aactttagct tatttaattc cgatttatat
    19261 aataaataaa ttattagggt ttgattatcc tataatgttt tatgtattaa atacaatatt
    19321 tattataatg tttacaagtg gcgcaagaat agcttataga gctataagaa tagtcatgaa
    19381 caagacatat tctagaggaa aggtttcaaa tatccttata attggtgcag gagatgcagg
    19441 agaaatggtt atacaggaac taaaaagaaa ttcagaactt aaaaaagtag cagtggctat
    19501 aattgatgat gataaagata aaattggaag aataatccat aatgtgaaaa ttgtaggaac
    19561 aacttcggat ataaaagctg tggtagaaaa gtacaatgta gatgagataa tcttttcaat
    19621 agcaaacata gagaaacgta gaaaaaaaga gattattgat atatgtaaaa acactaactg
    19681 taaaataaag acaataccag gaatttacga aattatagat ggaaaagttg atataaaaca
    19741 gattagagaa gtagagatag aagacttgtt gggtagagag cctataaaaa caaatttaag
    19801 agagataagt aattacattg agggaaaagt aatcctaata actggaggag gaggctcaat
    19861 tggttcagag ctttgcagac agattgcagg atttaatcct aaagagctta ttatagttga
    19921 taattatgaa aataatgctt actcaataca acaagaatta cttagaaaat ataaaaataa
    19981 attagattta aagacagtaa tagcatcaat aagagaagaa aaaagaatgg atgaaatatt
    20041 taataaatat aaaccagaag tggtatttca tgcagcagca cataaacatg ttcctcttat
    20101 ggaatcgagc cctggcgaag ctataaagaa taatatattt ggaactttaa acatagctgg
    20161 cttgtcttca aaatatagag ctaagaaatt tgtccttata tctacagata aggctgtaaa
    20221 ccctactaac ataatgggag ctactaaaag agctgctgaa atgattatac agactatgaa
    20281 tgctgaaagc cagactgaat ttgttgctgt tagatttgga aatgtgcttg gtagtaatgg
    20341 tagtgtaatt ccacttttta agaagcaaat tgaagatggc ggaccagtga cagttactca
    20401 tccagatatc attagatatt ttatgacaat accagaagca gtaggcttag ttatacaagc
    20461 tggggctatg gctaaaggtg gagaaatatt tgtgcttgat atgggagaac ctgtaagaat
    20521 attggattta gcaaaaaact taattaaatt cagtggattt gagccagatg ttgatataaa
    20581 aattgaattt tctggtctta gaccaggaga aaagttgtat gaagaactac ttatgtcaga
    20641 agaaggtctg ttggatacag agcataaaaa gatttttatt ggtagaccaa tagatgttga
    20701 tagagaaaaa ataacaaaat acttaaaact tttaagagaa attactaaca atgaagaggt
    20761 tgaaaaaata gatggtatta tgagggaatt agtgccaact tatattaaac cagaagatgc
    20821 taatatcaaa gaaattgcaa caactagaga aaagtagaat atatttctaa tttgtaacca
    20881 gggggagcaa aaagaaacaa atatatacta aaaagaaaca aaagattaca aaaagattac
    20941 aaaaagatta caaaaaaggt tgcaatttat tttgatgtaa gatagaatgt taattaggaa
    21001 ttggaaacga aggaacaaaa tgttaaattt tcgaaaggat taggtatttg agattatgat
    21061 gaatattaaa aataaaaaac atatattgaa aaaatttata gctatggtgt taatagcagg
    21121 agttgtcaca gtagaagcag gagcaataac ggctagtgca gcagagccaa ctaattcacc
    21181 tatgagtgca acagtagacc agtgtgattt tttaaatgta agaagtggag ctagtgcaaa
    21241 tgatgcagta gtaggaaaga taaacacagg agacaaagtt gaagttttag aattacattc
    21301 aaatggatgg attaaaataa aaagtgttga caatgttaca ggatgggtaa atggagatta
    21361 tttaactatt caaggtggaa atgtagatgc aaaggtacaa aatgttttaa acttagcatt
    21421 taagcaacaa ggtaagccat atagatgggg agcaactgga ccaaatgctt ttgattgttc
    21481 tgggttcact tcttatgtct ataaaaatgg agcaggggtt aatttaccaa gagtatcaag
    21541 atcacaagca acagtaggaa agaaagtatc aagagcagaa ttaaaaccag gagatttagt
    21601 tttctttggt tcaggtggtt caataaatca tgttggattg tatgtaggag attctaaatt
    21661 catacattca ccacaaacag gagatgtagt aaaagttact agcatggctc caggaactaa
    21721 ttatgcaaga agacttataa ctgctacacg tgttttacaa taataataga tattgattta
    21781 cataggattg aatattaaca ttaaatatat aattacattt aatgttttac atagagattt
    21841 aagagtttag taatattaaa atagtgatga acgttataaa aacagcaaag aagataaatt
    21901 tctttgctgt tttttttata ataaattatt tcatattata atcaaatatc aaatataaat
    21961 tttaactata ttattcaata tttgacagat aatatgaatt ttagatatac ttaataagaa
    22021 gtatattgta gaaaaaataa atttaaaaaa ttaaggggga tgaaatgaaa aaaataagta
    22081 tattagtatt atcattgata atgacactta ctatgtgtag tgtaagttca tttgccgatt
    22141 catcaaatga taaggaaatg agagctgctt ggatatctac agtttataat ttagactggc
    22201 ctaagactaa gaataatgaa gccaagcaaa aaaaggaata cacagattta ttggacaaac
    22261 taaaaagtgt aggaataaat acagcagtgg ttcaagtaag accaaaatca gatgctttat
    22321 ataaatcaaa tataaaccca tggtctgaat atcttaccgg tacacaaggt aaagaccctg
    22381 gatatgaccc attaccattt ttaatagaag aagcacataa aagaggaatg gaatttcatg
    22441 catggtttaa tccatataga ataactatgg cagatgagag catagataaa ttgccagcaa
    22501 accatccagc aaagaaaaat ccaagctggg tagttaaaca tggaaataag tattactacg
    22561 acccaggttt accagaagtt agaaagtaca tagtggatag tatagcagaa gtagttcaaa
    22621 attacgatat agatggagtt cattttgatg attacttcta tccaggagta agtttcaatg
    22681 atactgcaac ataccaaaaa tatggaaaag gacaaaataa ggataattgg agaagagaaa
    22741 atgtaaatac tctacttaga gatgtaaaag cgtctataaa gagtataaag cctaatgttg
    22801 tatttggtgt aagcccagca ggtatatgga gaaataagag tagtgaccca acaggttcag
    22861 atacatcagg taatgaaagt tatgtaggta catatgcaga tacaagagca tggataaaac
    22921 aaggattgat tgactatgta gttccacaac tttactggcc aattggtctt aaagcagcag
    22981 attattctaa attagtggca tggtgggcta atgaagtaaa aggaacaaat gtagacttat
    23041 acataggaca aggtatatat aagcaaggtc aatctagtta tggtggacaa aatatagcaa
    23101 aagaaatagt acaacaagta acattaaata gaaagtatag tgaaataaaa ggtagtatgt
    23161 atttctcagc taaagatata gcaaatagta cttctataca aaaggattta aagagtttat
    23221 attctagtag tgaagaacca gttactccac catctaatgt taaagtggag aaattaagag
    23281 gcgacgaaag atatgacaca gcagtagcaa taagtaaaaa aggttgggct acaaattcag
    23341 atacagtagt attagtaaat gggtactcta tagttgatgg cataacatca acaccacttg
    23401 ctacatcaaa tgatgctcct atactattgg taaataagga taatatacct acatccacta
    23461 agaatgagtt aaaaagactt aatccaagta aagttatttt aattggagga aataactcta
    23521 ttggagataa agttgagagt gagataaaag atacattgtc aaatgtatca ataaatagag
    23581 ttggtggttc agatagatat agtacatctt taatgatagc aaaagaatta gtaaaaacta
    23641 atccagtaga aaaactatat ataacaagtg gtacaggtga agcagattct ctttctatag
    23701 cttcaaaagc aggagaagaa aagcaaccaa tagtactagt atcaaaagat aatgtaagtg
    23761 atgaagttta caattggata tcagatttaa aagtaaaaga tgcttatttt ataggtggta
    23821 atctaagtat atctgattca gtaataaata agctggataa ggtcattaca aatgatgtat
    23881 ctaaaaatag aatagctgga gaaaatagag aagaaacaaa tggaaaagta atacaaaaat
    23941 tctatccaaa tgctgaatat tcatcaatgt ttgtaagtaa aagtaatcaa ttggtagatg
    24001 cattaacatc aggtccttta gcagctaaat taaaatcacc agtagttatg cttggaaata
    24061 gtgtaacatc tgctcagaaa actgctttag agcctaagaa aactgctcta gtatacgaag
    24121 ctggagatgg tataaatcaa aacacattaa acactttctt aaacttagtt aagtaataaa
    24181 aaagttaatt taaaatacag agtattttat aaatgtagat taaaatgaaa attatcatca
    24241 taaattagaa aataaaaaag aactatatgc attttgtaat caagtgtaca cagcaacttg
    24301 aaaataatta tgcgatatag ttctttttta gtaattaatc ttatactttt taataaactt
    24361 tatgttgaat tttttattgt ttaaactcta tgtcattaaa tataaaatcg tgtaatatgt
    24421 ctaaagtatc tgggtcaaat ctaagaaccc atccagcttt tccatatata ccacctgtac
    24481 tatgaatttc atcatcaata ggaaattcaa attgcttaat atttaagtca cccattttta
    24541 aaacttgagc tcctaaagaa agtattgcat taggcttcat gttagtttta acatatggaa
    24601 gaactgcatc taataaacct ggatatttag taacaggtaa agtttccgtt ttcttgatta
    24661 tagcttgtat aatctgtctc tgtctgccat ctctagcaaa ggctgtatcg ttgtgtctga
    24721 tacgtgcaaa agatagtgcc tgatatccat ttagagtctg ctttccagag tttctaatgt
    24781 attgtatgct acctttatca tcacttttat tccatttata agtttcagga ataaatttat
    24841 ttagttctcg tatttctcct ttttcaacag taacctcaac gccaccaata gcatcaatta
    24901 tatacataaa tgattcgaaa ttaacacaag cataattttg aatatcaata ttaaaattct
    24961 cttcaattgt ttgtattaat aaatcagctt gtccataagc ataagcatga gtaagttttt
    25021 gtttaccatg accagggatg tctacatagc tatcacgagc taatgatgta agtttgatat
    25081 cattgtgttt gttatcaata gtaagtatca tcatagcatc tgaccttgaa gaatcttcat
    25141 ttggtctagc atctgttccc ataagtagta tgttaattat cccatcttca tttttatggt
    25201 cattgttatc caataaatca ctacttatgc tcgagtcatg aatagcagat aatttataat
    25261 aaaaatatcc atagacactt atagggaata ttactaccaa gaaagccagt agtataacaa
    25321 atttctttaa ttttgacaaa agtacccctt ctttcttctt tttcctgtat attttttaat
    25381 agcatacact taattatatt aaagtattga gatatattca atacttgttt cagttacaaa
    25441 aaaaagacaa tgatataatt tataagaaaa tttatcgacc tatatgtata gttaaaagta
    25501 tatataatat attttttaaa agtaatttat attttaaaat aaaaacacac cccataaata
    25561 caaagcaatt tgcatttaag aggtatgtat ttatcatcaa attattggtt tgttttggaa
    25621 tttctaatct tcaaccataa tatctttaaa tatgaaatca tgcattgcat ctagttcata
    25681 ttcctcaaaa ggtattacat agcctgcatt acctattttt ctaccatttt cagtagaaag
    25741 aggaaactcc atagatttca aatttaaatt tcctatactt aaaagttctt ttcctaaaga
    25801 tattatttca ttaggattca tattagtttt tacatacgga agtattgtgt taactagatt
    25861 aggatattta gtgactggta aatccttaac accatttatt aaactctgta taacacttct
    25921 ttgtcttcta tctctttcat ctgtactatc attttttctt atacgagaaa atgcaagtgt
    25981 ctgatatcca tttaattttt gctcaccaga atttcttata tatttaagag aacctttatt
    26041 gtcattttta ttccatttat aagtttcagg aataaattta tttaattctc ttatttcact
    26101 cttatcaaca gtaacagtaa ctccacctaa agcatcaact atatccataa aagagaaaaa
    26161 gtcaactacg gcgtagtttt gtatatcaag ttggaagttt tcttctatag tttctattaa
    26221 taagttagct tgtccatata cgtaggcatg tgttaatttt tgttctccac gtcctggtat
    26281 atcaacataa gtatctctat ttaatgaagt tagcttaaga cttttatttt tattatcaat
    26341 agtaagtatc atcatggcat cagaacgaga aacttcttct cctggtcttg catctgtacc
    26401 taacaataat atgtttgtga tattttcttc gtttttatag tcattactac taagcgcctc
    26461 tgtatttata ctatcatctt gtatagtttt taatttagta aaaacatatc catatatact
    26521 aacaggaaat gctataacta aaagggctag aaatataacg aactttttga gtcctgacaa
    26581 taatatcccc tactttctaa attttttaat tacacatagt taattatatt aaaaatttgt
    26641 tacataagca ataaaaaaca caataaatta gcataagttt gtcataatat aattattttt
    26701 atagtatttt atagaagaaa gtgtgtagtt attattgatt ttattggaat ataattgtat
    26761 gaagacttaa atttttataa actgatgtgt atattgaaaa aaatattttc ctgaatgtag
    26821 ttatagcatc ttatgaaagg tgtaaattgt aatttaaaat ttttagtgta taataagaat
    26881 tgaaaattca aaccgataaa aattaataaa aaataattat aaattaataa tttgggggag
    26941 gaaatgtatg ataaaattaa tagcaacaga tttagatgga actttgttag atgaaaagag
    27001 cgaaataaat ccagagtttt ataaagtatt taaaaaatta agagagagag ggataatgtt
    27061 ttctgctgct agtggcaggc agtatcaaaa tcttataaaa aaatttgaag atataaaaga
    27121 tgatatgatg tttatatcag aaaatggaac actagtagta tataaaggaa aagaaatatt
    27181 atcaaatcct ttaaataaag aattagtaaa tgaaatcata gagacaacaa gaagtataaa
    27241 agggaaaaaa attgtaatga gtgggaaaaa atacgcttat atagaaagca aagatgaagc
    27301 gtttatacaa gaggttagta cttattatgc aaagtttaaa attgtagacg atttgacgaa
    27361 agtagaaggc gatatattga agatagctgt atttgacttc aaaggtgcag aacataataa
    27421 taatatctac tttgaaaagt tttctgatag agctcaagta tgtatttctg gagtggagtg
    27481 gcttgattta actgcaaaag gtgcaaataa agggagtgcc ataaaaaaag tacaaaaaat
    27541 gttagatata aaatatgaag aaactatggt atttggtgac cagttaaatg atgtggaaat
    27601 gatgaaaagt gcctatcata gttatgccat ggaaaatgca aatgaacatt tgaaacaaat
    27661 tgctagattt agagcaaaaa gaaatactga aaatggcgtt gtagataaga taaaagaggt
    27721 cataaaaatt ggatagtcat atgtatagat gaaaaagatt attttgaaga aatcaaaaaa
    27781 atatcaatgt aattttgata aataagttta tttatgcgaa aattacattg atatttaata
    27841 aacatcaata atagatattt atttttttat gatattcagt attttgtttt ctatttgagt
    27901 tgcattttca gcagaaatta aataaacata tctacctgct ttctcaatta tagtattatt
    27961 tgctatttca gaattgattt tttctccatg tccttctcca aaaggtgctt gtatcatatc
    28021 ttttttataa ttttctagag ttttatatat tttatctacc tcgtcagttt ttataacgat
    28081 aatatcttct agagataatt tttcagaaga attaattaca aaaccttgaa ttatgtcttc
    28141 ctctacatca ttaaaatagt taaagtcctt tgcatcaaag atttttgatt cttttataag
    28201 taaatcagaa gattttaatg ctttttttat ttttgatgta gaaacgtttt tgtaatcacc
    28261 acttgaagaa caactaacca ttcctaatga taagattatc gaaaaaaaca atattaaaat
    28321 ttttttcatg ataaacctcc aagtttttta aactctgtct taaattagtt tactacataa
    28381 ttatataaaa ataaatgtat ttaatgttac agttttgatt aataatgtaa tattttgata
    28441 ataataccta ttgagaggtg attagaaatg agaataccaa aacatgtagg aattataccg
    28501 gatggaaata gaaggtgggc aagtcaaaat ggtatgacaa aagataaagg atatgaaagt
    28561 ggaatagacc ctggattaga gtcttataga ttatgtagag atttaggctg tgaagaggtg
    28621 actttttatg gatttacaac tgataataca agacgtccat cagtgcagac aaaagctttt
    28681 acaaaagcat gtattgatgc tgcaaatata ttaatagatg aaggtgctgc tttattagtt
    28741 gtaggaaata caaaatctcc aatgtttcca gaagaattat taccatatac taatagaatt
    28801 aaagccaaag aaggtcaaat aaaagcaaat cttctggtaa attatgggtg gtattgggac
    28861 ttaaataata tatcaggagt agaaaatgta aataaaaata atatacagga ttacatacag
    28921 tcatttgatg tatccagact agatttaata atcagatggg gtggaagaag gagattaagt
    28981 ggtttccttc ctgtacaatc aatttatgca gatttttatg ttatagataa ttattggcca
    29041 gattttaaga gtgacgatat aaaggacgca tttagttggt atgatacaca agatgtcact
    29101 ttaggtggat aattaaaaat attctgattt aaggttgtag agtgttttaa attattgaaa
    29161 aaaaaacttc ttgatggtaa aataacacta ataatatgta aaagtgtaaa aatttatacc
    29221 aagaagggtg aagaaatgtc aaaaggcaat aataacaata attcaagaaa caaatctaaa
    29281 aagaccagtc atctgaatag aaaaaagcga aaattaaata agaaaaagtt agcagtgttg
    29341 atttgcttta cagttttatt tttatttatt gcatttaagg ctactcaagg tgtagtagct
    29401 ttggtaaaaa gtatggataa aagtaataaa actagtcaac aacaaaaagt taactcagaa
    29461 caatttgacc ttggtaatga agaggaaaat aaaaagaaaa aatatactgt atttatagac
    29521 ccaggtcatg gaggcaatga taaaggaact gaaagcaaga ccagtaatag atatgaaaaa
    29581 gacctaaatc tacaaattgc aaaaaaatta gcaaataaat tatctaaaca aaaggatatt
    29641 caagtagtag tatccagaac tgatgataca tatatatcat taaaggatag agctatctta
    29701 gcaaataata gttctgctga tgtgcttgtt tctattcatt taaatgcaga gaaaaatggt
    29761 aatacagcaa caggtataga aacttggtat aggaataaag ctacagatgg ttcaaaagaa
    29821 cttgcacaga cagtacaaag tactatagta tcctatgtta aagttagaga taggggaata
    29881 gttgaaaata actttgaagt acttagagaa tcaaatatgc ctgctatatt aatagagtgt
    29941 ggttttttaa caacaccttc agaggaacaa aaaataataa atgaaaaata tcaagaccaa
    30001 cttgcggaag gaattgttca aggtgtactt tcatacctag attctaaagg gaataagtaa
    30061 gttaacttta ctttaatgtg aggataaatt taaaagttta actgtgtaaa ttgtattaac
    30121 tttatttcgt aatgttggaa acattgtttg aatttagaaa ctatgaaatt agaaattatt
    30181 ttatctatat ctaatttcat agtttttttt gcaaaaaatt tatagttata aaatttaaaa
    30241 aaataaattt agtataatgt aatgtagtta tttatatgtg attttaactt gcattgattt
    30301 gctatcaatt gtgctttata attagtatat ataaagttta actgtaagat aatttaaaaa
    30361 ataggggaat ttatatgaat aaaaatagca tgacaaaaat ttacagttta aataaaataa
    30421 tttttattat aattggaatt ttaggaatag ttttacttac aagacatatt gaggtagata
    30481 ttaaagtttt aattttaatt ttattaactt tgtttagtat aaatgtattt atttcatatc
    30541 ttaaaattaa gttgtatgag gataaaatta atttaggatt gataaataat tcagataagt
    30601 ttataaatat tactaaagat gagaacttcc taaaacatgt tcaaaattat attatcagta
    30661 atgaaaaaga aaactgtgta atggcttgtt ttgatttatg tagactcaaa cttataaatg
    30721 atatatatgg ttatgagcta ggggatgaag tgttaaataa tattttaagt aacttaaaaa
    30781 attattttgg aaaagaagct atttatggaa agttaaaaag tgatgttttt gtattaataa
    30841 taaagcttga aaatagggaa cagaagattc cttatttagt aaatcttatc aagaataaaa
    30901 ttatgatatt aagtcagatt gacagtttta aaatggatat aaatattgag gcttctattg
    30961 gaatttataa atttaacaat aatgaaattg atataaaaaa agctatagat aatgctgata
    31021 tggcaaggct taaatcaaaa ggactaaagc acatagagta tgtagaattt gataatgcta
    31081 tggaagaaga aatacaatca attatgaaaa tagagagaga tttattcttg gctattaaaa
    31141 ataaagagtt tgtaattcac tatcaaccta aagttgattc aagtacaggt aacattatag
    31201 gttcagaggc attgataaga tggttgcacc catcattagg catggttgga ccaaataagt
    31261 ttatacctat agctgaaaaa aatggtctga taaacaatat tggtagatgg ctaattcaag
    31321 aagtttttat taccattaac aagtggattt cagaaggtat aaatgtctta ccagtctcaa
    31381 taaatctttc tagagtagaa ctatataaaa atgatttagt tgattttttt aaactgatgt
    31441 ttaatacata taatattcca aaagaactta tagaattaga aattacagaa acgacagcgc
    31501 taagagatgt aaaatttata agtgaaaggc tttatgagat taaatcttta ggtatgaata
    31561 tatcattaga tgattttgga gtaggtaatt caaattttat caatcttaag gggataccac
    31621 tagatattat aaaaattgat aggtcactta tattggatat agttacaaat acaaaaacaa
    31681 agtttatggt gaaagcaatt attaaccttt cacatgattt aaacgtaact gttatatgtg
    31741 aaggggtaga ggatatgcat caggtcaaag tcttaagtga actgggatgt aatttcatac
    31801 aaggttatgt attttttaaa cctttggatg agatgaatta taaaaaactt cttactgacg
    31861 gaagttatat aaatctgaaa gatactcttt tagataaatg catgacagtt gaggaggagt
    31921 aaggatgatt tcagaagatg tagattattc aataagaatc ataagagcta tatttaataa
    31981 tggagaagat aaaccaatag atgctaaaat gatattaaaa agtgaagata taccaatact
    32041 aacactatac agactgctta gaaagctttg tgcaaacaat attcttactt ttaacaaaga
    32101 agatggcaag acatacatgt taaatgtgtc attggataca ataagtctaa gaactattgt
    32161 agaagtaatt gatggaaaaa tatatataaa taaatgtacg agatatgtat ctaattgcag
    32221 taattgctta aaaggttgta aagtaaatcg tgaattgcta gaaatagaaa aagaaattta
    32281 taaactttta tcgagaaaat ctataagaca aatactagaa taaaaaattt tcagctatga
    32341 taataattgg aggttttcgg ttatggatga tatatctcaa gataattttc tactgtctaa
    32401 agagtatgag aatagcttag atgtagatac taaaaaagca agtggaatat attatactcc
    32461 taaaataatt gtagattata ttgtaaaaaa aactttaaaa aatcacgata taattaaaaa
    32521 tccatatcca cgaatacttg atatttcctg tgggtgtgga aattttcttt tagaagtata
    32581 tgatatttta tatgacttat ttgaggaaaa tatatatgaa ttgaaaaaga agtatgatga
    32641 aaattattgg actgttgata acatacaccg tcatatatta aactattgta tatatggtgc
    32701 tgatattgat gaaaaagcta taagtatatt aaaagatagc ttaacaaata aaaaggtagt
    32761 aaatgattta gatgaatctg atataaagat taatctattt tgttgtgata gtcttaaaaa
    32821 gaaatggcga tataagtttg attacatagt gggtaatcca ccctatattg gtcataaaaa
    32881 acttgaaaag aaatataaaa aatttctcct agaaaaatat agtgaagttt ataaggataa
    32941 agctgactta tatttttgtt tttataaaaa aattatagat attttaaagc aaggaggggt
    33001 tggcagtgtt ataactccaa gatatttctt agaaagtcta tcaggtaaag atttaagaga
    33061 atatattaaa tcaaatgtca atgttcaaga aatagtggat tttttaggtg caaatatatt
    33121 taaaaacata ggggtatcta gttgtattct aacttttgat aagaaaaaaa caaaagagac
    33181 atatatagat gtatttaaaa tcaaaaatga ggatatatgt ataaataaat ttgaaacatt
    33241 ggaagaactt ctaaagagta gcaaatttga acattttaat ataaatcaga gattgctatc
    33301 tgacgaatgg atacttgtaa ataaagatga tgaaactttt tataataaga tacaagaaaa
    33361 atgtaaatat agcttggaag atatagcaat aagttttcaa ggaataatta cagggtgtga
    33421 taaagcgttt attttaagta aagatgatgt aaagttgaac cttgtagatg ataaattttt
    33481 aaaatgttgg ataaaaagta agaatataaa taaatatata gtagataaaa gtgaatatag
    33541 gctaatatac tcaaatgata tagataatga gaatacaaat aaaaagatac tagatgaaat
    33601 tatagggcta tataaaacaa aattagaaaa cagaagagaa tgtaaaagtg gaataaggaa
    33661 atggtatgaa cttcaatggg gtagagaaaa gcttttcttt gaaagaaaaa agataatgta
    33721 tccttataaa tcaaatgaaa atagatttgc tatagattat gataacaatt tttcaagtgc
    33781 agatgtatat tcttttttta taaaagaaga gtatttagat aaattttcat atgaatatct
    33841 agttggaatt ttaaattcca gtgtttatga taaatacttt aaaataactg ctaaaaaaat
    33901 gagtaaaaat atatatgatt actatcctaa taaggttatg aagataagga tttttaggga
    33961 taataattat gaagagatag agaatttatc aaagcaaata atatcaattt tattaaataa
    34021 gtctatagat aaaggaaaag tagaaaaatt gcagataaaa atggataact tgataatgga
    34081 ttctttaggt atataagcag ttgtaagtat taaaaaatta taatccttta attgtttatt
    34141 taaatttaga aataaaaagt tagccatata aaaaatatta aaaatatata cttttcaata
    34201 tttttttgat aaaataagaa tgaatttgtg caattttatt tttctccaat aactaaaaat
    34261 agttttttga attaatattt gcttaagaat aaaaatcaga aacgtttttg atatagtagg
    34321 tgataatatg aaaggattag ttttagaagg tggaggaaca aaaggagcct accaaatagg
    34381 tgcatataaa gctttaagag agcttggtat agagtttcaa ggagtaactg gcacatcaat
    34441 tggtgcttta aatggagcat atataattca aaatgatatt gaagtaatgg aagatatttg
    34501 gttaaattat gactatactc attttatgaa tattgataga gaaacctatg agaggtttaa
    34561 aaatgtagat ttcactacta aaaatctcaa tgcagtgttt gagcttataa ataaagctag
    34621 aaaaaatgaa ggtatagata taagcccatt aagacaacta atggagacaa cattaaatga
    34681 agacataata aggaaatcaa aaaaagactt tggacttgtt acggtctggt gggataaaaa
    34741 aattaatcca tatccattgt atatcgaaga tatacctaaa ggaagattga ttgattattt
    34801 aattgctagt tccagtttgc ctatttttca aacgaacatg atggatgata agttgtatct
    34861 tgatggaatg ttttgtgata acatgccaat aggactcttg gaagacaaag gttatgaaga
    34921 tgttgttgta attaggttga ttgatgattt tattgggaaa atgaatctaa atcgacatca
    34981 aaatataaat ataaaaacta taataccatc agaatatcta ggaggttctc ttaataaaga
    35041 tagagataat gtagaaaaaa acatccgact aggttactta gatactatga aagcatatga
    35101 aagatgcact ggaattaagt attattttga tgtagagtat aaatataatg aagaatattg
    35161 ttttgataaa tttagaagta tgagcaatga aacaatacaa tatatctgta atttattgaa
    35221 tataaaaaga gatgcttcac ttagaactgt tatggaaagt gtaataccaa agcttggtga
    35281 ggtgcttgga ttgccaaagg acttttcata taaagatttg ttttactgta tatatgaaaa
    35341 gaaacttgaa gaaaataata taaacaggat aaaattatat gattttaaca aggttataga
    35401 tgttgtaaat acaaatattg attctaatag aaatttagct tctaattttg aagttagacc
    35461 taaaattagt attaaaaaga acaaaaacac aaaattattg acaaattgta ttataaaaga
    35521 cataaaaaat caaagttaaa taaaaaacaa aaaaaaattt gtaattatac tcgaaaaaag
    35581 tgtatattag tagtataata tttttgtagc actagtggga acaaaaaatg accataggac
    35641 aaaaaagtac cacttagtac cattaaagta aaaaacagga aaacaatttt aaaaaatata
    35701 aaatgtaaag tttataggag gatttaaaaa atggaaaaag tagttagtat caaaaatgca
    35761 agtggattac atgctagacc agcaggaatg tttgttaaga aggcagctga atttaaatca
    35821 acagtagagg ttgtagcaaa agacaaaact gtaaatgcaa aatcaataat gggaataatg
    35881 agtttaggtt tagctcaagg agaagaatta aagttagttg taaatggaga agatgaagaa
    35941 gtagctttag ctgcaatggt tgaattagtt gaaagtggat ttggagaata gatataataa
    36001 ttttttaaaa tttgatattt agaatctaat attacttaaa gtaaagtaac agagaagtat
    36061 taaacatata cagaccaaca tttgtagata tttaatttct ttgttacttt catgtttatt
    36121 taatcagaag attaagacta ttgttaattg ggtataaaaa tataaatatt ttagaaaatg
    36181 aaataagata tttttaatca taaattcaga gtaaaaatac agtaacaaac agtttataaa
    36241 atttaataaa aaattataag taaataaaac tataaaaatg taaattattt atataaattt
    36301 atagagttta tgtgctagat gatatttttt aggaggtagg gttatggctt acaaaggaat
    36361 aggtgcttct cctggtgttg ctttagggaa agcgttagta gttgaacata gtgaattagt
    36421 aattgaaaaa aaatctatag ataatgttga agctgaaatt gctaaattag aagatgcagt
    36481 tgcagtttct aaagaagaat tagtaaaagt taaggaaaag gcttctgaag aattaggagc
    36541 agaggaagca gaaatatttg aagcacattt attagtttta gaagacccag agttaattgg
    36601 ttctgcaata gataaaatta aaactgaaag tgtaaatgca gagtatgctt taaatgaaat
    36661 aaaagagatg tttgttagca tgtttgagtc tatggacaat gagtacatga aagaaagagc
    36721 ggcagatata aaagatgtta caaatagaat acttagacat atattaggaa ttaaagttgt
    36781 tgatttatct gctttaagcg aagaagttgt attaatagca catgatttaa ctccatcaga
    36841 cacagcaact atgaataaaa aaatggtttt aggattttta actgatatag gtggaagaac
    36901 ttctcatact gctatcatgt ctagaacttt agaaatagct gcaatcgttg gattaaatga
    36961 tataacttca aaagttaagg atggagattt tgtagttttc aatggagaca caggtgaagt
    37021 aattgtgaat cctgatgaag agactataaa taaatatact gaattaaaag ctaagtatga
    37081 agatgagaga aaagcattac agctattaaa aggaaaacca tctgtaactt tagatggaaa
    37141 acatgtggaa ttagctggta acataggaac acctaacgat atagaaggtc taataaagaa
    37201 tgatgctgaa ggtgttggtc tttatagaac agaattttta tacatggata gagattcttt
    37261 cccaacagaa gaaatacaat atgaagcata caaagctgta ttagaaggaa tggatggaaa
    37321 gccgatagtt ataagaacat tggatatagg tggagataaa gaattaagtt atttaagtat
    37381 ggaacctgaa atgaatccat tcttaggtta cagagcaata agactttgcc tagatagaaa
    37441 agatatattt aagactcaat tgagagcttt atatagagct agtattcatg gaagattaag
    37501 aatcatgttc ccaatgattt catctttaga agaattgtta caagctaaag aagttgtaaa
    37561 agaagtttta gcagaacttg attctgaagg tgtggcttat gctaaagatg tagaaattgg
    37621 tatgatgata gaagttccat ctgctgctgt aatatctgat gtattggcta aacacgtaga
    37681 tttcttctct ataggaacta atgatttaat tcaatacact tgtgcagttg atagaatgaa
    37741 tcaaaagata agttatcttt acaatcaatt taatccagct gttttaagac ttataaagac
    37801 tgttatagac aatgcacata aagaaggaaa atgggcaggt atgtgtggag aatctgccgg
    37861 agaccaaaaa atgataccaa tacttttagg tatgggatta gacgagttct ctatgtctcc
    37921 aatatcaata cttcctgcta gaaagttaat aacttcagtt aaagagtcag atatgaaaaa
    37981 attagctgat gatgtactta atatgggtac tgctgaagaa ataaaaagct atatagaaaa
    38041 gacttttaat atataattaa tgttatatag ttactaaaat tcatttttct aaataacaaa
    38101 attatatttt acgaattaaa aaggagatgt ttcaaaataa aaatttgaag catctctttt
    38161 ttataaaaga ttactaagaa ttacttaatc tttgtaatag tcattttgtg aaaaagcaaa
    38221 actgcattgt gactatagta tatatggatg ttattatcaa taaaagtact attaaaatga
    38281 agattcattc tcaaatgata tcaaaagtag ttgtgatgga gtaagataat attttgtgat
    38341 ttaatagtaa aaattaaaaa aatatggtat tgaaaaataa ttaaaagtat ttaataatag
    38401 aattagggaa gaataagttt ataagtaaaa ataattgatt actagttaat aaaataaatg
    38461 tgatatccaa ataaatccta aatctaattt gagttttaat atagatagtc taaagtttga
    38521 ttattaaaga tttaattgta agttgttaca gttgatgata ttgattagag attaaagttt
    38581 agagtagaaa gttaccttaa atttaaaaat gcaagataac ccaatctaaa aattataatc
    38641 actcgatagg tttaaggatt tatttgttta ttataaatag gagggtgtct caaaatgaac
    38701 tttttagttt atgaggcact ctcttttata tagaattaaa tatattttat tatttcaaca
    38761 atgaaaaaga agcttatctc tattttgaga cagcctcttt gtatactatt attaatttaa
    38821 ttaataatat aatttaaaat tataatatta gttaagattt cctgctttat tagtaaataa
    38881 ttctttaata gcattgtttc tggaaactaa atcgttatca gagttgtttg tttttttcat
    38941 aatcactgaa taacgttttt tatttataaa aaatattaaa atcttatcat catcaaaatt
    39001 gtattcttta tatctgtcaa tagactcata acctagattt agaatgtttt tgtcttttat
    39061 actatctaca tctaaaatat atgatgggtc agcctttagt aatatattaa ttaaacattt
    39121 ttcttcacca gcacagaata actccatctt acttgatata gatttagatt gctctgaagt
    39181 tatttttgca ggaataaggt tgtcattatc atctcttaga agataaccat gtgtgtcttg
    39241 ttgatatact aaattaacct ttttcttagg aacactaatc attttatcta aatgtacata
    39301 atgatgattt tcaacaaaac cttcatttaa tatttcaaca aagttattaa ttttacctag
    39361 gcaaaaagat tctatagatt ctttacagaa tttatttgta aatggtatta tgtttacgtt
    39421 ttcctcatct gtattccatg ctatagcata atccaacgaa tatacttctt cctctatatc
    39481 tgcaaaatta tattgtacta tgtttccttt caaaattact cgacctccat cttataatat
    39541 atttaatata ctttataaaa cttatattat atttaaataa tatcataaat tggataaata
    39601 tgatatagta aataagaaaa aatttgaaaa aaatcactat aaatgagtaa taaatataaa
    39661 tagtgtatac taatgggatg gaaaatgtcc actattaact ttattacccc acatatataa
    39721 gataaaatta ttaatataaa atataatcta tcgacaatga atagactttt aaataaactt
    39781 aatataaaat taattaaata agtgcttaaa aacgatttac tttaatgata gaatcatatt
    39841 aaaggaggat aattttatgg atataaagaa taaaattaaa tctatatttt taccagaaaa
    39901 aaatgactat ttagatgatg aagaatttga gtatgatata gaaaataatg aagaagattt
    39961 aaaggaagat aacaaagtac atttaaatga tttaagcaga gtaaaatatg attacagaga
    40021 gttaaaagac atagaaaacc aaacagaaga gatgtgtctg ctagcagtaa agcaggatgg
    40081 tactataatt gagtttgtaa aggacaagac ttataaagta tgtatggaag cagtaaaaca
    40141 gacatataaa gctcttaagt atataacaaa tcaaaatgag gatatttgta tagaagcagt
    40201 aaaacagaac tacagagctt tgtactacat aaataataag acagaaaatg tactaattga
    40261 ggctataaaa aatgcatcaa cttatgatgt catggaagta tttaaatttg tggaagatca
    40321 aacagaagat gtatgtctag catttataga aagggcatct aaaaatgatg ttgcagagat
    40381 attaaaagga ataaaagagc aaactccagc catatgttta gaagctgtaa aaaaagatgg
    40441 aaaatcttta gcttatgtaa aggaacaaag taatagtata tgtttagaag ctgtaaaaga
    40501 aaactacagt gcactatctt gtgtaaaaga gcaaacagaa gaaatatgta tagaagcagt
    40561 aaaacagaat gactttgcat tgtattatgt aaatgaacag acagaaaaaa tatgtatgga
    40621 agcagtaaaa agaagttata tggctctaca gtatgtaaat aagcaaacag aagagatttg
    40681 tttggaagca gtaagaattg atggaagagc attacagtac gtaaaagagc aaacagaaga
    40741 aatttgcttg gagtcagtta gacaaaatgg aaaagtattg caatatgtaa aaaaacagac
    40801 tgaaaatata tgtatagaag cagtaagagg ttcatttgaa gaacttgaaa taaaagaaat
    40861 attaagttat gtaaagatac caacagaaag aatatttgta gaagcagtaa agcaaaatgg
    40921 aaaaattctt aaatatgtag aaaatcagac agaattaata tgtttagagg cagtaagaga
    40981 aaactataat gctttagctt atgtaaagga acaaacagaa gagatttgtt tagaagcagt
    41041 taatcaaagt tatgaagcgc ttaaatatgt gaaagaacaa acagaagaag tttgtctaaa
    41101 agcagtaaaa caagattata gaatgttgaa atatgtaaat aatcaaacag aaaaaatatg
    41161 tttagaagca gtaaagcaaa attatagagc tttagaattt gttgataatc aaacagaaaa
    41221 agtttgtctt gaagcagtaa aacagaatag aaaagcacta cagtatgtaa aacaaaaaca
    41281 aagttaaaag gctaaaatat atagaaaata tatgcaaata aataaaattt gatattttgt
    41341 aataaataaa atgggtatct caaaatgaac tttttagttt gtgaggtact ctttttatat
    41401 gaaataaaat atatttttag ccttttaaca atggggaaaa ggtttatttc tattttgaca
    41461 taggcttttt atgcatataa agcttgataa aattgtttta ttataattgt tttgttatat
    41521 aaataataat aagaaaatta tataggtctt tttttgacca gttttgcatt tttaacaact
    41581 agttttgtaa agtatattga attttctcaa aaaagaatgt actctatata tgtaaaattt
    41641 ttttggaggt aaaaatgttt aaaagatatg ctgaaaaaat gacatctgtt ttaatttgta
    41701 ataatatgat agataataat gaatctaaag tctattctta tggatttgaa atattaatag
    41761 ctttcatagt taatataacc accatgctgt ttataggttt tttatttggt aaatttacat
    41821 atgtattatt ttttttaatg tgttattgtc caataagaca attttcagga gggtatcatg
    41881 cagacaatta ttttagatgc ttattaacct ttatttttat aattttatct acaatcttaa
    41941 ttatagaaaa tataaatata gacttattta aaaatattat tatgattatt gcaagtgtta
    42001 gttgggttgg aatttgtgtt ctgtgtccaa tagaacatag gagtaaccct ataagtgata
    42061 gggaaaagtt tgtttataag aaaactgcta tatttatatc tacagtagtg ttattgataa
    42121 caattttaag tctttctttg agtatatttg tagattattt cacatatagc gcatttgcca
    42181 tgttttggat ttttgtgatg ttagtattag gtaagttaaa agctaaagta taagtaaaat
    42241 atgtatgagg gagagttaag ttatgaaaaa gtttattgta agatttatga agtttgctag
    42301 ctcattggca cttagcactg ctattttgtc agctaatagt acctgtcctt ggattattca
    42361 tcagcctaaa gtacccaaag aaatcagcaa tctaaagaag acaaattaaa tacaagcact
    42421 tatttataca aaattatcag gaaaaaagaa attattatat tttaataaga ttaaaacaat
    42481 ataaaatcag atacaaaatt tattttattt attttatagg agcctaatac ctatttggta
    42541 atatattagt gcgccaattt agggggatat agtgtattta atgaaatgac ttacggagag
    42601 taagtcattt ttgtattgta tgtattttat gtaaacttat gatataatga agggtaaagt
    42661 ttaattaaaa taataaaaaa ctttagtata gatagtaatt taggaggtag ggtatgagta
    42721 tgatacataa attttctatg aatggatata atatcgtttt agatgtgaat ggtggagctg
    42781 ttcatgtgtt agatgatgtt gcatacgatt tgttagattt ttataaagaa aaaagtaaag
    42841 aagaaatatt agagatatta aaatcaaaat atcaagaaga aaaaataaat gaagcatatg
    42901 aagaaatatt aaatttggaa aaagaaggtc ttttatacac agaagataca tatcaatatc
    42961 atccaagctt tgtacataga gagcctgtag taaaagcttt atgtttaaat gtagctcatg
    43021 attgtaactt aaaatgtaaa tactgttttg cagctcaagg tgattttgga ggagaaaaag
    43081 aacttatgag ttttgaagtt ggtaaggcag caattgacta tttgattgct aattcaggaa
    43141 gtagaaagaa cctagagata gatttctttg gtggagagcc tttgatgaac tttgaagttg
    43201 taaaacaact ggttgactat ggaagaagtg tagaaaaaga ttataataaa aatataagat
    43261 ttacaataac tacaaatggt gtactgttaa atgatgagat tatagattat ataaatgaaa
    43321 atatgcataa tgtagtttta agtttagatg gaagaaaaga agttaatgat aatatgagac
    43381 caactttaaa tgataaagga agttatgata ttacattacc acgatttaag aaacttgtgg
    43441 aaaaaagagc aaaagataag tattattata taagaggtac ttttacaaga gataatttag
    43501 atttttcaaa agatgttatg cattttgcag atttaggatt taaattaacc tctgtagagc
    43561 cagtcgttgg agatgagagt aatccatatg cacttagaga agaagattta cctaagatat
    43621 ttgaagagta cgaaaaattt gctgtagagt atgcagatag acaattacaa ggagatggat
    43681 ttaaattttt ccattttatg atagacctaa atcaaggtcc atgtgtaata aagagaataa
    43741 ctggatgtgg agctggaaat gagtatcttt ctgtaactcc aaatggagat atctatccat
    43801 gtcatcaatt tgttggaaat gaagaattta aaatggcaaa tatatttgat gaagaaatag
    43861 tacttccaga aaatttaaaa aatatgttta gagaagctca tgtatatact aaagaagagt
    43921 gtaaacaatg ttggaataag ttttactgtt caggtggatg tcatgcaaat gcgataaact
    43981 ttaataatga catatcaaaa ccatatgaat taggatgtga aatgcaaaga aaacgtacag
    44041 agtgctctat aatgatacaa gctaagttaa tgttagaagg agcaaccaac taaatttata
    44101 ttttaaagga gttgtttata tatgattaga gattatttag aagataaacc tttaattgac
    44161 gaaagtgtat ttgtggcaaa atcagcagat gtaattggaa atgttaaaat aggcaaagat
    44221 tcaagtatat ggtacaatgc agtagttagg ggtgatgaag gaccaataac tattggagaa
    44281 aacactaata tacaagattg ttctatagtg catggagata cagaaactat aattggtaac
    44341 aatgtaacag ttgggcatag gtctatagtt catggttgta aaattagtga taatgtgtta
    44401 attggtatgg gttcaataat attggataat gctgaaatag gagaatatac tctgatagga
    44461 gcaggtacac taattacatc taataagaag tttccaccag gtgttttgat aatgggttct
    44521 cctggtaagg ttgttagaga gcttacagaa gaagataaaa aatatattga tgaatcttat
    44581 gaatggtatt tagaggcagc acaaaatcaa aaatattagt ttaaagagtg gttgtttcaa
    44641 aacatattta aatctgtttt gaggcaacca ctaatttatt ttattagatt ttgttgatat
    44701 tttagttttc aaaaagtatt tgattaaacc agatataaaa tgtcaaaaat aaaaattaac
    44761 tgagttaaat aattttaata aaattggtag tatatgtgat aaaattaaat attaaagagg
    44821 atataggata ttagaatatc aattggtgaa ataatgtcat atacgataaa ttaaggtgta
    44881 agtttttggg tatacctatc ttaggagtga aaagatttga gaataagtta tagaaattta
    44941 aagcgatata gagaaattgg atatgtttta ataaagtatg gttttagttt tattgtagaa
    45001 agactaaata tagaaggaat tgcctataaa ataccactat ttgacccacc agaagaaata
    45061 aaaaatatga caactggtga gagaatgaaa agagttttag aagaactagg acctacatat
    45121 ataaaaatag gacagatatt gagtacaaga aaagacttgt tagaccagga tataattgat
    45181 gaaatatcaa aactcagaga tgatgtagag aaatttgatt caaatatagc tattgatata
    45241 tttaaagaag aagtgggttt aagtatagaa gaaatattct tagaatttaa agaagaacca
    45301 atagcagcag cttcaattgg tcaagtttat gaaggtgtac ttaaaacggg agaagaagta
    45361 atcgtaaaaa ttcaaagacc aaatatagag aaaataataa aatctgattt agagattctt
    45421 agaactattg caaatacttt aaaagattta aaaaaggatt ttaatttaga tttagtacag
    45481 atgattgaag aatttcaaac tcaattaatg agggaacttg attatacatt tgaagccata
    45541 aatgcaacta aattctctag gatatttaaa aatagtgatg aagtatatat acctaaagta
    45601 tactcagaat ataatactaa gaaaatttta gtaatggaga aagttaatgg tacaaagtta
    45661 agtgatgtag aaaaaataag gagactaggt tataacacaa aaactattgt tgaaatagga
    45721 gttaggtcat tttttacaca ggtattatct catggatttt ttcatgcaga cccacatcca
    45781 ggtaatatat ttgtagttgc taaaaataag atagcatata tagattttgg aatgattgga
    45841 attattgata ataaaacttt aaaccaatta aatgaaattg cattagcagg tgtagaaaag
    45901 aatgttgaca agataatata tctattgata gaaatggatg cattaaatgg agaggctgat
    45961 attaagggac ttagacagga tttactttat ctaatacatt attactatga tatttctata
    46021 gaaaaaataa atgtaacaga tatattaaat gaactattta ggttttttag acagtataaa
    46081 atagtcatgc ctgcacaatt tgtaactctt gcaaagacag ttataacatt agaaggaaca
    46141 agtagaactt taaacacaga tttttctttt ggttctatgg gaaaagagtt tatgaaacat
    46201 cattataaga gtaaatttaa ccctaaaaat gttgttttaa gttcaagaca aaatgtagaa
    46261 gaaatattac tggacataaa aactattcca aagcaattaa aagcaatttt aaaaaatata
    46321 gaaagaaata atataaaaat gcaaattgaa gatgttaaaa tgacgaggtt agaaaattgt
    46381 ataatagagc taacatctca aatatctttg agtttagtgt tggcatctat tatagtaggt
    46441 tcttctctta taattgcatc tccaaatata gaaaataata tatggataaa atttactgca
    46501 atagcgggtt tctttatatc ctttataata ggcctttgct tagttataag aagtattagg
    46561 tcaaaataca aaaaagatta gggggaatta aatttgaaaa aatggatatt gaagtataaa
    46621 ggtaagatag aggaaagtga atttagcaaa aaacttaata tttccccgga aatctgccaa
    46681 attttaaaaa atagagggat atgtactgaa aaagattcag aaatatttat gaatccatct
    46741 ttagattatt taagagaccc ttttttaatg aaagatatgc aaaaagctgt tgatagaata
    46801 aagttagcag ttgagaagaa cgaaaaaatt tggatttacg gagattatga tgttgatggt
    46861 gtatcatcta catccatctt gtgtttatat tttaagagta taggttacaa tgttgattac
    46921 tatattccta atagattaga agaagggtat ggtataaatg aggatgctat taagcttata
    46981 agctctaggg gatgtgactt gattataagt gttgactgtg gaattacatc agtgtctgag
    47041 gtcaatacag cgaatgattt gggcatagat gttataatta cagaccatca tgaatgtcaa
    47101 agtgaaattc catcagcctt tgcagtaata aatccaaaac aagaagattg taattatcca
    47161 tttgattcac tatgtggatg tggtgtagca tttaaaatga ttcaagcctt gactccaaaa
    47221 gaagaattta aaactagtat gtataattat ttggaaatag taacactagc aactatttgt
    47281 gatattgttc cacttataga tgaaaataga ataattgtaa aaaatggttt aaaatcaatg
    47341 aaagaaggca aaaatattgg attaagggag cttataaaag tttgtggtgt agaaagtgat
    47401 aagataggtt cttctcatat aggttttgca ataggtccta ggataaatgc ttcaggtcga
    47461 ttgggatatt cttacttagg agtagagcta tttactactc agtcacaaga agaggcagta
    47521 gaaatagcta gtatattgga agaaaaaaat aatgaaagac agatgataga agctaagatg
    47581 tatcatgaag ctgaagaaat gctaaagtct aatagcagat acaatgatga caaagtgttg
    47641 gttttagcca aagagggttg gcaacatgga ataataggaa ttgtagcatc aaagttaact
    47701 gaaaaatact acaaaccaac aattcttcta ggtatagaaa atggggaggc tactggttca
    47761 gcgaggtcaa taaaaggatt taatatattt gaagctctca taaagtgcaa agacttgatg
    47821 actaagtttg gtggtcatga acaagcagca gggttatcct tggattcaga caatgtagaa
    47881 attttagcaa atgaaataaa taaatttgca gattataatt taactgaaga tgatatgata
    47941 gagaatgtaa atgtcgagtt tgaattacaa gaaaatgtaa taaatttaaa tcttgtagaa
    48001 gaattacata agttagaacc ctttggatta aataatccta atcctagatt tatagttaga
    48061 aattatattt taaaagattt gaaagttata ggtaagaatc aacaacatct gaaattaagt
    48121 atagaaaaag agaaaagcta tgaatgtata ggatttaata tgagtcattt aaaatcaatg
    48181 tataaagtag gagacaaagt agatgtacta ttccaattag atgaaaataa ctatatggga
    48241 aataggaaag tacaattttt acttaaagat atacgattgg ctcgacctaa aagtgcaagt
    48301 aatgacaaac tttcattgaa attaatgtca aaaataatac caaaagatac tcaaagcctg
    48361 tataatatat ctgtgtctga ttttgaatta tttgatggaa atacagatat aaatatattt
    48421 gattattttg aaaaagatac actaataata tctaattcta taaatggatt ttatagagca
    48481 atgtcagata tatcacttat agatttggat tttaacataa attacaatat tattgaagat
    48541 gttagcaaaa atactgataa attagagctt atattttctc ctaatattga taaaatagac
    48601 ttaaaaagat ataataatat tattctttat gattatttat acaataaagg cgaatattcg
    48661 tatatatatg agaataaaag agaagaaagt gaaattataa aatattataa taaaacagac
    48721 ctattatatt taaagaatgt agttagtaat atagttccat caagagatga atttataaca
    48781 atttataaac aagcacttat aaaaaaagaa attgatttgg atatggtaaa tataagggaa
    48841 acttttaatg taattccatt aaagtttttt acgatattaa atgtatttag agaattaaat
    48901 ttacttgact ttaatttaaa ttatgaaaaa aattctgtac tcataagaat attgccaaaa
    48961 ccacagaaaa aattagactt aaatgagagt ttaatactca ataatctaaa aaatttagaa
    49021 aaacaataca atagcagtta ttaggaggcg tttcccatgg atttaaaaaa ctttataagg
    49081 aatattgatg atttcccaaa accaggcata gattttaaag atgtgacaac tctatttaaa
    49141 gatggagatg catttaaata tgcagtggat tctatagttg aagaattgaa agataaagat
    49201 gtagatttag taatagggcc agaagcaaga ggatttttga tgggtacacc tgtagcatat
    49261 gctttaggag taggatttgt tccaattaga aaacctggaa agttaccagg tgaagttgag
    49321 agttatgagt atggattaga gtatggtaca gatactttag agatacataa ggatgcaatt
    49381 aaaaagggtc aaaaagtagc aatagtagat gatttattgg ctactggtgg gactatggaa
    49441 gccgctgcca agcttgtaga aaaattaggt ggagaagtag tttctatgca atttttgatt
    49501 gagctaaaat tcttaaatgg gagagaaaag ttgtctaact atgatgttaa ttctcttata
    49561 aaatactagt acttttataa tagttggtat aacaccaact attttcatat atattaaaat
    49621 tttatacaaa ataggtggtt atatgcatga taaagaatta caagaaataa ttgaaaaaat
    49681 aaaagtttat gcacctaatg caaattttga aatggttgaa aaagcctata atcttgcaaa
    49741 aaaagcgcat gaaggacaat atagaaaatc tggggaacca tactttattc atccattagc
    49801 agttgcaaat attttaatag agatggaatt agatattgaa actataacag caggtttact
    49861 tcatgatgtt gtagaagata cagaatatac ctatgaagac ataaaaaaag aatttggcaa
    49921 agaagtagcg gatttggttg atggagtaac taaacttggt caaataaaat atcgttcgaa
    49981 agaagaaact caatctgaaa atttaagaaa aatgtttttg gcaatggcga aggatataag
    50041 ggttatactt ataaaacttg ctgatagatt gcacaacatg agaacattaa aatacatgcc
    50101 tccagaaaaa gcaaagtata aagcaaaaga gacacttgaa atttatggtg gtatagctca
    50161 tagattagga atttccaaga taaagtggga actagaagac agagcattaa gatttatgga
    50221 cccagaaggg tattatgatt tagttagtag agtatcaatg aagagaagtc aaagagagga
    50281 ttatattcaa ggaattgttg aacttcttaa agataagttt aaagatttaa gtataccatg
    50341 tgatgtatat ggtagaccaa agcattttta cagtatatat agaaagatgc aaaaaaaaca
    50401 taagactttt gaagagattt ttgatttaac agcagtaagg atattggttg ataatgtaaa
    50461 ggattgctat gcagtacttg gtatagttca tacattatgg agacctattc caggaagatt
    50521 taaagattat atagcaatgc caaaacccaa tatgtatcaa tcattacaca ccactgttgt
    50581 aggtcctgat ggagaacctt tagagataca aataagaact catgagatgc ataatatagc
    50641 tgaaaatggt atagcagccc attggaaata taaagaaggt atctctagca aagagtcaaa
    50701 ggttgaagaa aaacttcaat ggttgagaca gatgatggag tgggaaaaag atttaaaaga
    50761 cccacaagag tttatggatg cacttaaaga agatgtattt aatagtcaag tttatgtatt
    50821 tacgccaaaa ggagacgtaa ttgaattacc agcagaatca acacctatag attttgccta
    50881 tagagttcat acaaatgtag gtaataaatg tgtaggagct aaaattgatg gaagaatagt
    50941 tcctattgat tataagcttc aaaatggtaa tattgtcgag gtacttacat catctaattc
    51001 taatggacca agtagggatt ggcttaatat agtgaagacc ccaaatgcaa aaagtagaat
    51061 tagacaattt ttcaagaagg aaagaagaga agaaaatgtt gaccgtggaa atacaatatt
    51121 agaaagagaa tttaagaagc atgatatacc acaaaaagac cctcttgttg aaaaatatat
    51181 ggcattagtt gctaagaaat ttaatcagcc aagtgttgag gacttaattg ccactgtagg
    51241 ttatggcggt ataatgtcat ctcaagtggt atctaaggta aaagacctat atttaaaaga
    51301 ggttaaaaaa gctaaaaagg aacaacagat acaagaagaa gatttaaata aacacaatat
    51361 aagtgaaaca gaatacagta aaaagagaaa gaaaaacgca tcacaaggaa ttatagtaaa
    51421 agggcttgac aatatcttag taagatttgc taagtgttgt aatcctcttc caggagatga
    51481 aattgtagga tatattacta agggtagggg agtagccata cacagagctg attgcccaaa
    51541 tgcaaacaat aatggtgatt tcttccaaaa tagattggtg gaggtttcat ggagttcagc
    51601 aggaaaaggt aagtttgaag cggaaattca aataaaagct attgacagaa gaggaattgt
    51661 taatgaaata actcatattg ttgcaatgga taaacttagt ttaaacggaa taaatgcaag
    51721 aaaaggtaag gatagtattg taagtataaa cttacttgta gaggttaatg acacagagga
    51781 attaaaaatt ctaatgaaaa aattaaaagc aattcctggt gtagaaagta tttatagaat
    51841 gacaaattag agttaaaata atagggagga aactatgaga gcagtagtgc aaagagtatc
    51901 ttcatctaaa gttacagtag atgaaaacac tataggtcaa ataaataagg ggttactagt
    51961 attgttagga gtgactcatg atgataaatc aagtgatgta gattatatga ttgataaaat
    52021 attgaatctg agaatttttg aagatgaaaa tgacaagatg aatttatctc taatggatat
    52081 aggtggagag cttttagtag tatctcaatt tactttatat ggagattgca gaaaaggaag
    52141 aagacctgga tttagtaatg catctagacc agaacttgca aataaccttt atgaagaatt
    52201 tgtaaaaaaa gcaaaagata aaggtgtgac agttggtaca ggtcaatttg cagctcatat
    52261 gatggtagag ttaactaatg atggtccagt aacaatacta ttagactcaa gtaaatcttt
    52321 ttaaggggga aaactttaat gattataaaa aaatttgtag atagttattt tggagtaaat
    52381 acttatgtat taggtgatga aaagactaaa aaatgtgcag ttatagaccc aggtggaagt
    52441 ttagtagaga cattaagttt tgtaaaagaa aatgaattaa atattgaata tattatcctt
    52501 actcatgggc atggagacca tataggatat gttaaggata ttaaagaaaa aactggtgct
    52561 aaagtagttg cacatgttga tgaaaaagaa ttattaaatg ataaaaataa aaatctaagt
    52621 tatacaatga gatgtggagc gcaagagttt gatgcagata tctatgtgag tgataaagac
    52681 aagcttgaac ttggtgaatt aaaaatgact ttcttgcata ctccaggaca tactcaagga
    52741 tgtatgtgta taagagttga agatgaaatg ttcacaggag atactttgtt tgctggaagt
    52801 attggtagaa ctgatttata tagtggagac tttaaccaaa tggaaaaatc acttaagaaa
    52861 ttatgcaaat atgaagatgc tgttagagta tatcctggac atggaccaac cagtactcta
    52921 ggggttgaaa agaagacaaa tccttacatg taattttata ttagtattta aaaaagtata
    52981 aaatatttaa taactatatt agtgaggggg ttcttctact gttaaataga aggagttaag
    53041 ttgatgttgt atgttttttt aaaaggacat gattataagt atgaagtagc agaacttata
    53101 aaattgttta ccagtgaatt taagtttaaa gactctaatg ctaacaataa tatagagtca
    53161 aagcatttaa taaatagatt gatttatgag aatggtgtat tattctcaag tactgaatac
    53221 tatgaaaatg gaaatttaaa gtacgagtca atacagaata tagaaaatat gaatcttgaa
    53281 tttttagatg gatttgatag tagcaaaacg attgaagaat ttcttaatag actagatagt
    53341 gaaagtaaga ggaactttaa aaagctgtgt aaagaaaata tcaaaaaaag catgtttgta
    53401 gtgcttaaac aagtatttaa ttcttatgta ccatggggaa ttttgactgg tattagacca
    53461 gtcaaaattg tccacaattt aatggataaa aagctagatg ataatagcat aagaaccatt
    53521 ctaaaagata attattttat aatagataag aaaatagatt tagctcttga aatagctaaa
    53581 agagagcgat tatttatgta tcctatagat aaaaataaaa tttctcttta tgtaagtatt
    53641 ccattttgtc caactagatg tgtatattgt tcatttcctt caaattcatt aaaacaattt
    53701 ggacatttaa aaagagaata tgtttataaa ttgattgaag aaattaaggg gtttgccaaa
    53761 gttattaagg agactaagaa agaagttgaa actctatata ttggtggtgg aactccaact
    53821 acacttgatg aggaagaatt agatttgctt ataaattcat tgttcaatga attagattta
    53881 agtaaaatta aagaatttac tgtagaagca ggtagacctg acactattac agaacaaaaa
    53941 ctaagagtgt taaaaaaaca caatgttagt agaattagta taaatcctca aactatgaat
    54001 gatgatacct tggtaaagat tggaagagag catagagtat ctgatttagt agattgcttt
    54061 aatatggctc gtagaatggg atttgataat ataaatatgg atataatttt aggtcttata
    54121 gatgaagaat taaatatggt aaagaacaca ttggaggaga taaaaaaact ttctcctgaa
    54181 agccttacag ttcatacatt agccataaag agagcatcca acttaaatat aaatatggat
    54241 aggtataaag aacatctaac acaatatgaa gaaatggtaa aaatgataga tttatcaatg
    54301 aaatatgcaa aagatatggg attaaatcca tattatatgt acagacaaaa acatatgttg
    54361 ggaaatttag aaaatatagg ttatgctaaa gaaggatatg agtgcattta taatatacag
    54421 attatggaag aaaaacaaag taactatgca ttaggtgcag gtgctatatc gaaatttgtt
    54481 tatgtagatg aagatagaat tgaaagagta gaaaatgtaa aaaatgttga acaatacatt
    54541 gaaagagtag atgaaatgat aaaaaggaag aaagaagagg tatataaaaa tgttgactaa
    54601 agctcctaga ggaactaaag acataactcc aaaagaggct tacaaatggc gttatgtaga
    54661 aaataaattt agagaaatat gtgctttata tggatatgaa gaaatggtaa cacctatatt
    54721 tgaacataca gaacttttca agagaagtgt tggagatact acagatatag ttcaaaaaga
    54781 aatgtattct tttaaagata aaggtgatag agaaattacc ttaaagccag aaggtacagc
    54841 aggtgtagta agagcattta tagaaaataa attatatgca gatactcaac caacaaaatt
    54901 attttatgtg acaccttgtt ttagatatga aagaccacaa gctggtagac aaagacaatt
    54961 tcaccaattt ggaatagaag cacttggaag tgatactcct tcaatggatg ctgaaataat
    55021 cgcactagct gttcaatttt ttaatgaagt tggattaaat gatttggtag tgagtataaa
    55081 ttcagttggc tgtccagttt gtagaaaaga gtacaatgct ttattaaaag agtatcttga
    55141 ctcaaaagct gatatattgt gtgatacttg caatgagaga agagaaaaaa atccaatgag
    55201 ggttatagac tgtaaaaatc ctacatgtaa agaaaatatc aaagatatac catttattgc
    55261 agaccatttg tgtgatgatt gtaaatctca ctttgataaa cttcaagaat acttaaagga
    55321 aatgaatata aactttgtaa ttgataaaac aatagttaga ggcttagatt actatagaaa
    55381 aactgctttt gaaattatat ctaatgatat aggagctcaa agtactgtat gtggtggagg
    55441 aagatatgat ggtcttgttg aacaattagg aggaccaaaa ggtataagtg gaattgggtt
    55501 tggactagga attgaaagac ttttacttac acttgaaggt aatggaattg aaatagaaaa
    55561 ccctcaatct acggatatat ttatagtaac tataggtgaa gaagcaaata caagaagctt
    55621 taaattatta aaagacttga gacaaaatca tataagtgca gataaagacc atatagagag
    55681 aagtgttaaa gcacaattta aatattcaga taaaataaat tcaaaattta caatagtgat
    55741 tggagatgat gagcttaaaa atgacactgc gacattaaaa aatatgaaaa catcagagca
    55801 aactactgta aaattaagta cattagttga agaattaaag caaaagctgt aaaataagaa
    55861 agtatgatgt tttgtgtatt agataaatat atagcattaa aattaaataa aatggaggta
    55921 gtatcttgga aactttaaag ggtttaaaga gaactcacta ctgtggagag ttgagagaaa
    55981 aaaacataaa tgaagaagtc gtacttatgg gatgggtaca gaaaaaaaga aatttaggtg
    56041 gtcttgtatt tgttgattta agagatacaa gtggattatg tcaaatagtt tttgatacag
    56101 atgtagataa agaagctttt gaaaaagctg aaaaattagg ggctgaattt gtaatagctg
    56161 taaaaggaaa agtatgcgaa agacaatcta aaaaccctaa tatgccaact ggtgatatag
    56221 aaatatttgc aactgaactt agacttttaa acaagtcaga aactccgcct atttatataa
    56281 aagatgatga tgatgtttct gaagcactaa gattaaaata tagatactta gatttaagaa
    56341 aaccatctat gcaaagaaat ttaaaattaa gacataaagt aatgaatatt acaagaaatt
    56401 acttatcaaa caatagattt tgcgaaatag aaacaccatt tttaatagct ccaacaccag
    56461 aaggagcaag agattatcta gtaccaagta gagttaatcc aggaaaattt tacgcattac
    56521 cacaatcacc acaattatat aaacaattat tgatggtaag tggtatggat aggtatttcc
    56581 aaatagttaa atgctttaga gatgaagatt taagagcaga tagacaacca gagtttacac
    56641 aaatagactg tgaaatgtct tttgtcgagc aagaagatgt tatgagtatg attgaaggtt
    56701 tgcttgaagc gatatttaaa gaagttttag atgtagaatt ggcacttcca cttcctaaga
    56761 tgacttatgc agaagctatg tctaaatatg gttcagataa accagatact agatttggat
    56821 atgagttaac agatatatct gatgttgttt gtaactgtgg atttaaagtg tttgctgatg
    56881 ctacacaacc aggaaaaagt gttagaggta taaacgtaaa aggcaaagct gacgacttta
    56941 ctagaaaaca aatatcatca ctagaagaac atgctaagac atatagagca aaaggtcttg
    57001 cttggatgaa agtaggacaa gaaggagtaa cttctccaat agcaaaattc tttaatgaag
    57061 aagaaatgaa cgctatactt acaaaaatga atgctgaagt aggagattta cttttatttg
    57121 tagctgataa aaactcaata gtatttgatg ctttaggaca agttagactt gaagtagcaa
    57181 ataggcttaa tctattggat aaaaatgtat ataacttact atgggtaact gagttcccag
    57241 tttttgaaga agatgaagaa acaggcacat tttcagcaat gcatcaccca tttacatcac
    57301 ctatggatga agatttagac aagttagaag aaggtgataa gtcatcttta agagcgaaag
    57361 cttatgatat tgtattgaat ggttatgaaa taggtggagg aagtgttaga atatcaaatt
    57421 ctgatattca atcaagaatg tttaaagcac ttggtttcac agaggaaaga gctaatgaaa
    57481 agtttggtta tttattagaa gcatttaaat atggtactcc tcctcatgct ggtctagctt
    57541 ttggtcttga tagacttgtt atgttacttg caggaactga taatataaga gaagttattg
    57601 cattccctaa aaatcaaaat gctgtttgcc ctatgacaaa tgctcctaca ttggcggaag
    57661 atgagcaatt agaagaatta agtataaaag ttgatataaa agataatgaa taatatgtag
    57721 ttgcaagaaa ctaaaatgta aaaagtctgg atataaagta tatttatatt cagacttttt
    57781 ttattagaat tattttatat tttttctcta tatattttca taaattatcc ttgtattctc
    57841 agccaatata attaaaatac tatgtttaaa aattttacat aaacttgatt gttttagaaa
    57901 ttacttctgt aatgagtaca cgattttaat taaagaatat ataacaaatt tgaaataagt
    57961 ctaatatatg acttaataga ttaaattaaa ataataaatt tggactattt atctatttat
    58021 aacttaaatt atatcaaatt gataacaaac tagatattat acttttttgt agaatagaat
    58081 tacaattata taaagaaaaa ttctattaat agtgaaaaaa aagtagaaaa aagtagaaat
    58141 tattctttta taaagaaagg gagggataat attgcaagag agagaagaat tagttttaaa
    58201 tccagttcca aaagaggaaa gagttggatg gttagctcca ttgtttaata tgcttggttc
    58261 taacatagct atatctgaac taatggttgg aggaacttta attttaggaa tgactctttc
    58321 taatatgatt attacatcaa ttatagggaa cttaatatta gttgcaatca ttatgataca
    58381 aggttatata ggttacaaag aagggttaaa tacgtatgta ttagctaagg gggcatttgg
    58441 agagatagga ggaaagtatc ttatatctct attacttggt ataactagtt ttggatggtt
    58501 tggtgtacaa gcaggggttg caggactatc agtacaaaag atattcccaa gtgtaaacct
    58561 aacattagtt acagttatac ttggattatt tatggttgtt tttgcactgt atggctttaa
    58621 agctatggct aaatttaatt acttagttat accaccactt atgatattaa tggtgtgggg
    58681 agtttttaaa gctttttcta cttatggagt tgaagctatt tataattata ctcctcaaac
    58741 aactatgagt atggttgaag gtcttaatat tgtagtaggt cttgttatag ttggtgcaat
    58801 tatatcacct gaccagttaa gatatacgag acgagtaaaa gatatttgga ttatcagttt
    58861 tttaggtcta gggattattt cattattcca acaagttgca gctggtgtaa tgtctatggg
    58921 agcacctact tgggatataa cagaagtatt ggctaattta ggttttggat gggtagcgtt
    58981 tgttatttta atacttgcat cttggtcaac aaacgtatca aatgcttatt ctggtggatt
    59041 agcattaaaa actatttttc caaatgtaaa aagaaatgtt ttgactttag ttgcaggtct
    59101 aataggtaca ataatagcag ctactggtat aatatttaaa tttcagtcat ttttatcttt
    59161 cttgggaatc gcagttcctg caatagcagg aattatgtgg tgtgagtatt attttataca
    59221 aggaagaact tataagcata gagaaggaat aaattggatt gcagtaataa gctggttaat
    59281 aggttttgca gcgtcgtatt atagttcaaa aataaatttc ttaatacctc cgataaatgg
    59341 aattgtagtg agtatggtta tttattatat attaatgaaa tgttttggaa tcaaagataa
    59401 ataaaggggg caattacatg ggtcgtaagg tgaaaatagg tataattcaa caacacagtg
    59461 tacttggaga tgttaaaaaa aatatagaaa aagcagtaga gatgatagat gacttaggaa
    59521 aacatggggc agatataatt tgtttaccag aactatttgc tacaggatat aatttagagt
    59581 ctttaggtgg agttaaaaca ttagaattaa taagagaaca taataagtac atagaggaat
    59641 caatgtcaga agctgctaaa agaaataatg tatacctgat atctccatat ggaaccttag
    59701 aaaaagggtc tacacatgtt tataattcag cagttatatt tgatagaaaa ggtaagatta
    59761 tgggagaata ctgtaaaaat catctgtggt cattagaagc agtatacttt aaaggagggg
    59821 aaaaagtaga ggtatatgat gctgattttg gtagatttgg tgtaatgata tgttatgatg
    59881 caggttttcc agaagtatcc agagaattga cattaaaagg ttctgaaata atatttatac
    59941 catctgcatg gagaatacaa gatgaagata tgtgggattt aaatgtatct caaagagctt
    60001 tagagaacac tgtatataca gtaggtgtaa atttagtaag taatgactct aatttaatac
    60061 tatttggaaa gagtaaaata tgcaatccta gaggtactgt aataactcaa ttagatacat
    60121 acagggaaaa atatgtatta tcagagattg atttagatga aataaaaaag tatagggaag
    60181 atatacccta tttgaaagac agaaaaagta gctataacat ataattctat actataatac
    60241 aagttcaata taaaatgata aaaagaggat gtatcaatat taagattaaa tttattatat
    60301 tttgatatat cctctttaat attatcaact ttgatttaaa tatttttaaa atagttgata
    60361 agaaagtttt tgaacaacaa cacagcttta gattcatagt tttcgctaaa ccatgaaaga
    60421 tttaaatatc ttttaaattc aatatctttg atatgtaaca acttaatctc agggtcttga
    60481 gataatcccc atgattttcc acatataaat ccaactcctt gaagtgattt tataagagca
    60541 taaattgtat atggtgaatc agactcaaat gctattttgg gtttgaaatt agctgattcg
    60601 cacaggatat caattacctc tctataattc tcacccttcg ttataactat aaagttttca
    60661 tctgaaactt cgcttagata tacttcatcc tttaatgata aaggatggtt tattgaaact
    60721 cctaatagta tttcttcgca tgttaaagtt atgctatttt ctgagtttag ctttgtaaat
    60781 gaagaagata tgtacaaatc aaaatcactt tttttataag atgatggcaa agtatgtgac
    60841 acattaaaag taatattggg atatagtttt ctgaaattac tcaaaagtga tggtaacaca
    60901 ttagccgctg caggagataa tatctttact tctcctgaat tttctaaaga agtgtcttgt
    60961 aactcctttt ttgaactttc tactaaatct aaaatgctat ctactctttt tagaaacaat
    61021 cttccatact catttaaaac aatatatctt ccttttctgt caaataactg aactccaagt
    61081 tctttttcta aggaagatat agttttgctt aaagctggct gtgctatatt taacttgtgt
    61141 gatgcttttg ttatgtgctc cattctagca acagtttgaa aatacttaag atgcaataaa
    61201 tccatagtat aaaatacacc tcttttaata tgacttgagt tatatcaatt ttataatcaa
    61261 ctccacatta tacattataa tataaagttt atataatcaa ctacaatata ttaaaaagtt
    61321 atttaaattg ttatttatat tttgtacata atctaattaa aaaaagtagc tttaaatgat
    61381 taactaagga aatgttgtta caaactttag ttatataaaa aattcatttg atgagtaaag
    61441 tattaatgtc aagtaagaat aaaagcttat tagatagaaa aataatattt tataataatg
    61501 atgttactta aattattatg ttatactatt ttaaatagga aacatttaga tactataatt
    61561 ttagggggag tcaagatgaa attaactaaa tcaatatcat caatgctatg cttagctcta
    61621 gttttaagct tatcaccagt agcatatgca aatgaaataa gtagaacaac agtggagaat
    61681 actttagtag gtcaggacag ataccaaact gctgttgaag taagcaaaaa aggatggagt
    61741 agtgcgaatg aggctgtagt tgtaaatagt gaatctattg tagatgcatt agctgtaaca
    61801 ccatttgcta aattaaaaaa tgctcctata ttattgacag aaaaaaataa tctaaattca
    61861 caaactgaga aagaattaaa aagattagga gttaaaaaag tttatataat tggtctatct
    61921 agttctgtat caaatgatgt gcaaaaacag ttagaatcta ataatttaac tactgataga
    61981 gttggtggta gtgatagata ccaaacagct ttgagtatag ctaaaaaaat agaaggatta
    62041 aaagatatat cagaaatagc tgtagtaaat gggtacacag gtcttgcaga tgcagttagt
    62101 atagcttctg tagctgctac taatggaatg gttatacttc cagtatctga tgcatctggt
    62161 atatctagct ttaaagattt tatagaatct aagaatataa ataaatcata cataataggc
    62221 tctactaatg ctgtatcaga taaaataaaa caaagtttac ctaattcaga aagaataggt
    62281 ggagcagata gaaatgaaac taatggtaaa gtaatagaaa agttttatac atctaataaa
    62341 ttaaacaatg tatttgtggc taaggatgga atgaaaaatc aaaatcaact tatagacgct
    62401 ctagcagtag gagtactggc atcaaaagaa aattctcctg tactaatcgt aggagaacaa
    62461 ttaagtgcaa cacaaaagag tgtatttttg aataaaaatg ctacctctat aactcaagtt
    62521 ggtagtggag gaaatgaaaa tgcatttaaa gaattaaaag atttacaggc aaatagtaac
    62581 aataagagag taatgtatgt aactaataca gataaggtaa atataagaaa tgatgctaca
    62641 atagaagctt ctgttatagg atatctaaat aatggtgatg aagtagaagt tttagatgtg
    62701 ttaaaaactg gatgggtaaa aataaaatac aatgaaggta ttggatatgt tagtgggtct
    62761 tatttgacaa ataataagcc tgataatagt aatgaaaata taaaaataaa gtatgtaaaa
    62821 gaaaaagatg gtctaaatgt taggaaagga ccaagtacag aagatgaaaa aataggtcac
    62881 ctttcatatg gaagcaaagt agaaacaata gaaatatttg ctactggatg ggtaaaaata
    62941 aagtataatg gtggatatgg ttatgtaagt aatgattact tatctgatac accagttatt
    63001 taattataag taacaataaa aaactgcttt aatttgtaaa gcagtttttt tataaaaatt
    63061 taagtctaat aactatttct attttgatac cttaatcctg ggatttatta ttatggatat
    63121 tatcaacata caaacactcc aaatccagtg tctaattcca aacttagata ttaataaatt
    63181 cagtcctgct atggtaaata agcagtattt aattacaatt aaaagtgtat ttatagaaat
    63241 ccccttcata gaaagtatcc taaatccaat aatagacatt ctaagtccta taaatgccaa
    63301 taatatacct gcaatatcct gaattaagta atagtattca aatttcatat tcaatcaact
    63361 cttctctgag cagtatcaaa tatttctaac tcttcaattt catcatctgt gtatgtaagc
    63421 atagtaaaac cagttacacc ataaataaat gaaattatag gtgtaatcca acttaagaaa
    63481 caatatggaa taaattctag tgggcttaca ccaagagtct gagcacagaa aacagcattt
    63541 gaattccatg gtattaatgg accaccaagt gtagctgtat cttctataat tctagataga
    63601 ttttgtggtt ttaatttaaa ctctttgtat attggagaca ttagagttcc gacaaataca
    63661 gaagtaaaca tcattgatga actaaatgca tttgcaaagt agcttactat aaaagtagac
    63721 ccaaccaatt tagttcttga ttttcctatt ttagttataa gaggttgaag cagtacttct
    63781 aagaatccag ttttttggag aataccggca ataacgaaaa ctacaaatac tagtaaaacg
    63841 gtttcagcca tactcattat tccaccacga tttaatagtt tgtcggcata gacaaatcca
    63901 gtatctatag taaatcctga tagcatgtaa tttaaaatat cacctatttt ttctccttct
    63961 tgaaatactg ctataataag tcccatgata gctgaactta gtatagatat aatgggtggc
    64021 ttttgtagca ataaaagtaa taataaaaat attattggaa tcattgctac taaaccaata
    64081 tgaaagtttg aatttaatac atccttgatt tgatttattt gaacatagtc tatagtatta
    64141 tttgaatact taaatccaat tactgtatac agaactatac atattacgta tgcaggtcct
    64201 gtggtataaa acatatgctt catatgtgta attacatctg tcttacaaac tgctgcagct
    64261 aagtttgtag aatctgatag aggtgacatc ttatctccaa agaaagcacc agaaatgact
    64321 gcaccagctg ttaaaccaag aggaataccc atactagtac caatactcat cattgctata
    64381 ccagaagttc caagagtccc ccaagatgta ccagtagcaa cagaagttaa tgaacatacg
    64441 attaatgttg taagcagaaa atatttaggg gttattattg ttagtccact atatactact
    64501 gttggtattg taccagcagc tatccaagct gctattagta caccaacaga aagtataatt
    64561 aagtttgatt gaaaggcatc tttaccaact tcaaatccaa aagcttctat ttcatcatta
    64621 gtataaccaa gtttcgtggc tgcaggaact actataagcc atgaaagtaa aaacattgta
    64681 gttatagaag cattaaatac aactatacca actgatgtta gagctattat tgcaagcatt
    64741 actaacaagg aatatctaaa tgaaggtatt tttctttctg tattcatttt catagtgcaa
    64801 attctcctta aatattttta tttaattgca ttttttattc ttataagagc ttcttcaagc
    64861 atacttcttg gacaagctaa gtttattctt tgatacccac ttcctccaat gccaaagctg
    64921 tttccttgat ttagagcaac tttacctttt tgtacaagta cactttctag ttcctcatca
    64981 cttaatccaa gtgcactaaa gtctacccat aataaataag taccttctgg ttttctaact
    65041 ttaagttttg gcatattttc atttatatat tttatagcaa aatctatatt agattctaaa
    65101 tattctaaaa atgattctag ccaagattca ccattattat atgaagcttc agttgcaact
    65161 aagctaaagc aattatttct ctttatatca attctggtaa aagcatcatc taacaattta
    65221 tagtcttttt catcaggtag tattacatat gatgattgaa gaccagctat attaaaagtt
    65281 ttagttggag ccatacaagt aattgtattt ttttcaaatt ctttagaaat agatgccata
    65341 ggaatatgct tatgtttttt taatataatg tcactatgta tttcatcaga tatgattttt
    65401 acattatgct taagacaaat atctcctagt ttttttaatt catcttttgt ccatactcta
    65461 ccaactggat tatgaggatt acaaagtatg aataatttta catctttaat cttgttttca
    65521 atgtcttcat aatccattat atagtttcca ttttctagtt tctgtaatgg gcttataatt
    65581 agttctctat tgttattttt tacaacacta ttaaaagggc tgtaaactgg ttcttgtatc
    65641 attattttat catttgcttt tgtgagttca tttattaaaa gacttatagc tgggataaca
    65701 cctggactat aaattaacca ctcacttttt attttccagt tatgtctcct atctagccag
    65761 tttactatag attcattgta agaatctggt cttgttgtgt agccataaat ctcttgttct
    65821 agtctatttt ttaaggaatc aattatacaa ggtgcagcct taaaatccat gtcagccacc
    65881 cacataggaa gtaaatcatt agttccatac tttttttcca tttctgacca tttagatgaa
    65941 aaattattgc ttctatcaac aatctcatta aaattataat tcattgtaaa tacctccagt
    66001 aattttaatt ttatgttaat aatattaagc aaacaacgtg ccaatattga taataaaaaa
    66061 tatttattca caagttaata tttaatatta agtaatttca gagcatagat aagataaaaa
    66121 tattaattat acttaaaact ttgtggaaaa ggttatttct aataaatttt taaatatatg
    66181 aaaatgtaat taaataggtt aaataggttt aactgtttaa cttgttagac ctatttatat
    66241 tttttagaaa ttctactcct tttgatgtta taattgaacc tccacgacca acaagtatgt
    66301 ctacaagccc aaagtcttgt agttctaaaa gcatatttct aatctgttgt tctgtcaaaa
    66361 atctattttc ctctaaagct attttacata agctttttct acctattctt tcttttaaat
    66421 cataagcctt ttttaaatta tccaatataa atatgtattc atctagtgac cttttaaaat
    66481 tatagtcgta tttcatgatg tttttgtctt tgccaatgtt gaattgatac ttttttatat
    66541 tatcacttac tttattacaa acggttctac tataatttga atctatagtg tccaatatat
    66601 attcaggtaa atcacatatt tctataatat cttttcccaa gtaacagaag tattctccta
    66661 agtttcttaa ttctcttaca tttccttccc atctatacat tttaaagatt tcttttactt
    66721 cctcacttag aataaaatta catggaatat catattttaa tgaaccaaaa atttcaaata
    66781 tatcagcagc tctttcccta agtggatgta ttttaagggg aagaacattc aacctaaaat
    66841 ataaatctct tctaaacata tttttagata caagttcttt taaatttcta ttagtagctg
    66901 caattattct tacatcaata tcaatgacat tattagaacc aatacgtcgt acttgttttt
    66961 cttgtatgac tctaagtaat ttagattgag aatttaaatc catttctcca atttcgtcta
    67021 aaaatatagt tccattgttg gctaattcaa ataaaccaat tttcccacct tttttagcac
    67081 cagtaaaagc cccttcatca tagccaaata attcactttg cagtagattt tcttgaaaag
    67141 tactacaatt tactgcgaca aagggaccat cttttctcct agaagcacta tgaatggatt
    67201 gagcaaataa ttctttacca gtaccacttt caccaattat aaggatagat gaatttgatt
    67261 gagccatttt attagcaatt ttttttgtat taatagtttg tatactagaa cctaatatat
    67321 catcaaatgt gtatttactg atattaccag agtttactag ttgtgctctt aatttagctt
    67381 gctttttttc taattgagaa aactttgtca tctttagtat aaatccatca aatacattta
    67441 attgtatatg tttaatctct aaatttatat caatatgatt tattttaatc aatttctcaa
    67501 aaaatggagt tttattggtc aatatgtttt gaaaattgat gtcttttata caatcaccaa
    67561 caaatgagtc aatcatttca tttgcattta tagacaaaat ttttctagct atatgattat
    67621 agaattgaat tattccatca ttatttgtgc atataattcc atcatcaatt atagatagta
    67681 acaaatcaaa ttgtctttca aacttatttg catctaacaa taactcacct gtactataac
    67741 ttgtaggaat tattttttct acgtattttt ttattaggtc atcttttatt agatgtttta
    67801 atttggtttt tgtagcaatt tcaacaatac aacttaaatc tattattctg tattttaaat
    67861 ctacaacttc acaattttta aacttaggca ggattttttc gccaggagtt aggattacag
    67921 catctgtggg agtaaactca atctctggat agcagggcag gatatttata ttgtctattc
    67981 ctaatctatg tattaaagaa attgtttcta ttgccatatc tttacttaag ttatatacat
    68041 aaataatttt atctttttct aatttggata tcatatcaat actgttcttt tcaaatgtca
    68101 acttgggaac aatgatttga gcatcatagt gagataattt tactatttca tcgtatttta
    68161 aataagcaga taggagtata agtttttctt taaaaaactt taaatttccc tcttcaaatg
    68221 agtataaatt tatctttaga ttatcaccta agaattgcct tatttgattt tcataaattt
    68281 ctccagcgtc tttttttaaa cttacaatag ctaattccat ttgtttcatt ttaacctctc
    68341 atacaaattt gacttatttt agattacata ataattaaat tagattaaat aatattattt
    68401 aattattatt ataaatttat tatagactac acattgaagt aaaagaagta gctaaaatta
    68461 ttccttttat ttttgttttt tgtatctatt tggtataata gtattagagc gtataataat
    68521 ttaggcaaaa ttttttaagg aagactagag gagaatataa aatgaaaaaa tgtctttact
    68581 gtaataggga tataaagtca ccaaataata aattagctat aaaatatgat gacaatatga
    68641 atatatatcc atgtcgtgca gaatgtaagg aaaaaattga agaatatata gcaaaaaaac
    68701 ctacatataa gtttataaat atattagagg ttcttttagg tgtgggcgga atattctgct
    68761 ttttgagtaa atggactatt gcagcccaag ttgtacttgg aattgatgca ctggttatat
    68821 ttttattccc attggcagga tttaagatga atggaaagtt aagtatggaa caaactaaga
    68881 atcaaagtag gtctattgca atatcaattt tggcatttat agtaataata accgtattat
    68941 attttaaaca agttggtaag tagagcataa ttgtataaga catcattaga gtatgaggtg
    69001 agtttatgga agaaagaaaa ttagcaccaa acaatgagag ggaagctctc ataaaaagat
    69061 taaaaagaat agaaggtcaa gttaagggga tacaaaagat ggtggaacaa gaacgttatt
    69121 gtgttgatat attggttcaa atatctgcta taaggtctgc tataaataga gtaggcacaa
    69181 ttatcttaga gaatcatata aaaggatgtg tagcagaaag cattaaacat gatgatgctg
    69241 ataaaactga agagatgata aaagagctta tggatactat aaataaattt acaaaataag
    69301 gaggcggtta gttatgaatc aacaaggatt tattatggaa attgttgatg atagaactgc
    69361 aaagttaaaa atgcaaagac attcagcttg tgctgcttgt ggaaaatgtg ctactacaaa
    69421 ttcagcagag tcaaaagaaa tattagtaga agtagacaac acaattggtg caaaagttgg
    69481 tgaccatgta gaagtgagta tggataatat gaatgtatta aaagcagctg taatggctta
    69541 tataatacct cttatagcac ttcttgtagg aacaataggg acttattata tattgggggc
    69601 aattggaatg acaactggag ttgaagccat aagtggatta gttggaattt gtcttacaat
    69661 aatctgttat ttatacttaa agaagaatga caaaaaattt agagacagta gagaatttat
    69721 accagtaata acaagaatat taattgacct ttaagataat tataattaaa aaatagcaat
    69781 gtgcttttta aataaatact caatacgtat ttgtagagtt taagtacatt gctattttta
    69841 tatttttatt ttgattttct gtaaggaata aagttttttc tgattttcaa aagattcaat
    69901 gttcttacaa aagaagttac aactaataca ccaagtgcta ttgcagcact tagaaatagc
    69961 gcatctgtac cttttgacat agccaaagaa taatttttct gaatcaaaga caacattgta
    70021 ttatatagcc caattcctgg tattagagga agaatacctg gaattacgaa cacaatagct
    70081 ggttgcttta gttttcttgc taaagtctca ctacacgctg agaccaaagc agcagcaata
    70141 aaacctgcaa aaactgcatt tgtagtaaaa ttaaataaat aaacatatac aatccaacca
    70201 attccgccag ttactccagc tggaagaagt agatatagtg gagcattaaa gaaaacagca
    70261 aatccagcag ttgcaacacc tgaaaataaa aaatgcaaaa tcatagacat atcagtcatt
    70321 agaaaggacc tcctattcta taccatgtat caaggacaaa accaactcca gaagcaattg
    70381 caataataat catagcagca tcaaaagcac gagaaattcc tgatattaaa ttccctgata
    70441 ttaaatctct aatagctttt ataaaagcaa ctcctgggag tagtggcatt atagcgccga
    70501 ctataagcat tttagggtca tctaaaatgc ctatttcaac tagtagaact cctgaaagtg
    70561 caattaaaaa agaagatact aaacaggaaa atgcagatat tgcacttatc ttcatcgttt
    70621 tatcataagt aattgcagca aagattgcta ttataaacgt aagtataaaa tttaatacat
    70681 aattccctcc aagcaaacaa gcaaaacaag cagatgcaat tcctgtacaa gagtaaaata
    70741 accataaagg ataaggtttt acatcttgga tttcataaag acgtgcaatg gcattatcaa
    70801 tatcatactc tttgtcacta acaaattctc gagaaaaact gtttaataaa gaaatcttgt
    70861 ttaagtttat acctcttgat tgaatcgttt tcataaacga aaagccatca aatttctcat
    70921 ctgaaataat tattactgta ggagttgtaa aaatatttac atgataaaac cctcttgacc
    70981 tgcatattct aaggacactg tcttcaaccc tagatgtttc agctccattt tttatcatca
    71041 gttcccctac aaatagagct agttttagaa tatttttctt atattcaagt tcctcatttt
    71101 gattcataaa tacacctcca aattaaaaaa cgtaatattg aaattatatc aaatttttaa
    71161 gtaatattcc ttaatatcta tataaatata ttatcttttt tttgtttcaa aatagtcaca
    71221 tttaaattat atccaattaa aagaattaga caatattatt tattatattt taacttaaaa
    71281 ataaagaaag taactatgtt aaatatggaa aaatggcaaa acacttgact attaattggt
    71341 aaaggactat aataataaat tatcatattg ataaaaacga aaattatgaa atgtctgtaa
    71401 aaataaaatt taaataataa ctaggaggag taatatgttt gagaacttga aaaaagcgga
    71461 tcctgagatt tatgaaagta tgaaaagaga gttaaaaaga caacaaagaa atattgaatt
    71521 aatagcatct gaaaacatag tatcagttcc agtaatggaa actatgggaa gtcatcttac
    71581 aaataagtat gcagaaggtt actcaggcaa aagatattat ggtggatgtg aatacataga
    71641 tgaagttgaa actcttgcaa tagatagaat caaaaaaata tttggagcag aacatgctaa
    71701 tgttcaacct cactctggag caaatgcaaa tattggtgta tattttgcta tgttaaaacc
    71761 aggtgatgtt gttatgggaa tgaatttatc tcaaggtgga catttaactc atggtgctcc
    71821 agttaatatt tctggtcaat attataaatt ttatgaatat ggtatagata aagacagtgg
    71881 acttatagat tttgatgaag ttagaaagat agcacatgaa gtaaaaccta aaatgatagt
    71941 tgcaggagca agtgcatatc ctagagaaat agattttaaa aagtttagag agatagctga
    72001 tgaggttgga gcattgctta tggtagatat ggctcatata gcaggtcttg tggctgctgg
    72061 tattcaccaa aatccatgtg aagtggctga ttttgttaca acaacaactc acaaaacttt
    72121 aagaggacct cgtgggggtg ttattctttg taaagaaaaa tatgctaaag acatagacaa
    72181 agcaatattc cctggtattc aaggtggacc tcttgaacat ataattgctt ctaaggcagt
    72241 ttgctttaaa gaagctttaa gtgatgagtt taaagaatat caggtacaag ttgctaaaaa
    72301 tgcaaaagcc ttagctgaag aacttattaa aagagatttt aaattgattt ctggaggtac
    72361 agataatcat ttaatactat tagatttgat taataaaaat ataactggta aagcagcaga
    72421 aaagagattg gatgatgctt atataacagc taataaaaat acaattccat ttgatccaaa
    72481 tggtgctctt gttacaagtg gaataagact tggtactcca gctgtaacta ctagaggtat
    72541 gaaagaagaa gatatggcaa taatcgctga ggctatagac ctatgtttaa cttatgatga
    72601 agaatctaag gctagaacat tggttgttgg tttaactgaa aaatatcctt tatatgaaga
    72661 atataatatt atggattaat tataaagaac aactaaataa aatacattta aataattaca
    72721 atgattgtgt atgtatttga atatatttag atataaaaaa ggtgtctcaa aatgaacttt
    72781 ttagtttatg aggcactttt ttgtatggaa tcgaacatat ttgtgttatt taaataataa
    72841 aaaatatggt tatctctatt tttagatggt ctctttgtat tttttaatta aaactttaag
    72901 atttcttaag aattatacta ggtttttcta aagatttaaa gtctatactt ataagtatag
    72961 taatcatatg aaaagaaaag ctttaacgag gagggaatct tatgaaggta ttaattctta
    73021 caggaaaatt tggtatgggt cattactcag catcaaattc tttaagtgaa gatataaaag
    73081 caaaatttga taattcagaa ataacaatta aagatatatt tgaatacatt atgcctaact
    73141 attcagataa aatgtacaag actttttcta ttcttgtaaa tcggggaagt agtctttata
    73201 atttgtttta taaatgtgct gaaaatggaa agaaagatat aaaatttact ttttcagatt
    73261 attttttaaa taaattagat acattacttc atgaagtaca accaacagta gttatttcaa
    73321 cttttccatt ttgttctcaa ttagtatcaa gatataagga aaaatataac tcaaatcttc
    73381 ctttaataac atgcataact gatataagta gtcactcaga atggattagt aaaaatacag
    73441 actgttattt agtagctagt aaatctacta aggaagaact tgtttttaaa ggaatagatg
    73501 aatctaagat taaagttaat ggtattccag taaaaaaaga atttaaaaga atagaacatg
    73561 taaatcattc aactaaaaaa aatattctta taatgggtgg aggattagga ttactgccta
    73621 aatcagaaca attttacaaa gaattaaata gtttagaagg agtaaaaact actgtaataa
    73681 ctggtaataa taaaaaaatg tactataaac tatatggtag atatgaaaat atagaggtag
    73741 taggttacac caatgaagta tataaatata tgaaagattc tgaccttatt atttctaaac
    73801 caggtggaat aacactattt gaaacaattt attcagaact tccaatattg gcatttaatc
    73861 catttttaca acaagagata gataatgcta gttttatatt aaataatgaa attgggagaa
    73921 tacttggtaa aaataaaaaa tactatgtag atgagataaa agatttaatt tatgatgatg
    73981 ctactcttaa agaaatgagc agtaacatga aagaattaaa aaaacaattt gacaataata
    74041 ccttagagaa tattttattt tcacttgatg aacaaggagc gtgtagagaa tgtatgtagt
    74101 aggtttaatt atcgttgttg cattgatttt tttagtccat tcaattatac ctacatacta
    74161 taataaacta ttaaataaag aggtattaaa aaatatggct ggagaaaatg aaattgcact
    74221 tacatttgat gatggtccag ataagagata tacagaaaaa ttactagatg tgttaaaaga
    74281 aaatgatata caagctatgt tttttgtagt agcaaagaat gctgaaaaag agcctgaaat
    74341 tataaaaaga atgttgagag aaaatcatat agttggttta cattcattgg aacacagaaa
    74401 tgcatggctt tatagttata gttatgttaa aaaagatttt attgaaagta caaatataat
    74461 gaaaaattta ggtgtagatg taaactacta tcgtccacca tggggtcata ctaatatatt
    74521 ttcaaattca tttgttaaaa aatataatct aaaaatgact ttgtgggatg taatggcaga
    74581 agattgggag aaagatagta cagtagacat tattataaac aagttaatga gtagaacaaa
    74641 agaaaattct ataatttgtt tacatgatgc aggtgaaaat tcaggtggtg cagtaggtgc
    74701 acctgagcgt actattgaag ctttaaagat agctattcca aaacttaaag ccagtggttt
    74761 aaagttcgta acaccagaaa ggatgtagtt atgataagta aaactgaaaa gaaaaataaa
    74821 tgcctaggta gtgtagcttt tttagtttta ctaatgggca taacaggata ttttgttttt
    74881 agagggcagt cagttgaatc attgataaaa tcattaaaag gtgcaagccc tatgtttata
    74941 ctaattggat ttgcaatgat gtttatatat gttgcctgtg aaggtataaa tatatactta
    75001 ggtatgaaag ctttaaacca aaaaactact cttttaaaat gtatgggata tgcttttatt
    75061 ggattttatt ttagttctat tacgccttca gcatcaggtg gtcaaccagc acaagtttat
    75121 tatatgaaaa aagacgatat aaatatatca tattcttcac ttatactatt agtcattgtt
    75181 gttattcacc aagtagttat actggcatat agtggaataa tgttcattat ggaacgtgag
    75241 tttatattaa ataatgtaag tggtatgaac attttactaa tatatggtgt aataacaaat
    75301 gttgctcttg tcattggagt aattgcaatt atattttcaa aaaaacttgt aaacaatttt
    75361 ataatatcaa taacaaattt attaggtaag ttaagaataa taaaagatgt tgaaagttca
    75421 agaaaagtta taatatctca aattgaagag tatgttaaag gtgctcaata tataaagcag
    75481 aatccaaaac ttgtagtcca aattttagtc ataactattg tacaaataac agctatgttt
    75541 ttagttcctt tctttgtata caaagctttt catctatcaa catatactgt atttgagata
    75601 ttagcgatac aatccttgct taatattgct gtttcttcat taccattgcc aggggctgtt
    75661 ggagcttctg aaaatagttt tatgacatta tttaagatat ttttccctgg tcacttatta
    75721 gttccggcaa tgttacttag taggggaata agtttttatg catttgtagc tataagtgga
    75781 ttgatatgta tagtagtaca tgtaaaatct tctgaaaaag taaaagcagt gaaaaaagtt
    75841 gcttatgtaa gataatatta tatagattat ttttattaat atgtcaattt gtgtgtacat
    75901 tttaattaag ttttaaacat gtttacagga gtataaacta ttaaaacgtg tgacattgct
    75961 aagcttttgc taataaagta taatatttta tatagtttga aatatttaag aaatatagca
    76021 aaaaaaggag cttggtgatg aataaagaga ttccaaaaaa aattttagta gctgatgata
    76081 atcctgagat tagggaaatc gtagaaatac ttttaactgg tgaaggttat gaagttatta
    76141 tggcaacgaa tggagaagaa gctgtaaact tagtagatag tacgattgat ttgattattt
    76201 tggatgttgt aatgcctgta aaaacaggat ttgttgcatg taatgaaatt agagaaaaaa
    76261 cgacagcacc aatattattt ttaactgcaa aaactcaaga ctctgataaa gttattggat
    76321 tttcagcagg aggagatgac tatttatcaa agcctttttc atattctgaa ctaatttcaa
    76381 gggttaagtc gctacttaga cgttattata tataccaggg aaaggaaaag gaaagagagc
    76441 caaatatatt aaaaacaaaa gagttatgtg tcaatttaga tactcaagat gttacactaa
    76501 atggagaacc tgtgtttttg acaactatag aatatagtat attaattctt atgttgaaaa
    76561 atagaaaaaa agttttttcg tctgaaaatt tatatgaaac tatttgggat gagcagtatt
    76621 tttatacggc aaataataca ataatggttc atattagaaa tttaagaaaa aagttagaaa
    76681 aagaccaaaa aaatccacaa tatataaaaa ccgcatgggg aaaggggtat tatattgatt
    76741 aacaaaatta agccatctaa gttgggagtt atactattga tatatgtagt aatctcagct
    76801 gcagtggctt tcattttaaa tataccattt tactctgctg ttgaatctat agtaaaagat
    76861 gtatcagaag ggaaagtata ttttaaaaga gaagtaaatc aacttatgga taattttcaa
    76921 acttatgtga ataacaatgg tataagagca gatgatggag atgatatagc aaaatggaat
    76981 agtgataatt ggtttgtttc tatgaagata tataaaggaa ataaggtttt ttatgataca
    77041 ttatactatc ctaatgaagt acctgataag agtgaggaaa atgagtttta tagcagtccc
    77101 atggctagaa actatgagat acaattttct gatattaaag ctaatatagt tgtagtagct
    77161 ttatttagat ttagatttca aaattttata gaagcaattt ctattacatt tatggcactt
    77221 acatttatta taacattttt actgttgttt agtagaaaga taaagtacct aaggaaaata
    77281 gaaatgggta taaagatagt agagagtggc agtttaaagt atagaatccc agtaaaaggt
    77341 aatgatgaat tatcatcact tgcatctagt attaatgaga tgagtcatac attggagaat
    77401 caacttataa aagaaaggga gatgaagaat aaaaataaag atatagtaac ttcgatatca
    77461 catgatgtta gaactccatt aacatcagta atttgttatt tagatttgat caaagaccat
    77521 aaatacaata gtcctgagca attggaacaa tacataaaaa atgtaaggtc taaagcatat
    77581 caaataaaag atttaacaga tgaccttttt acgcattttg ttaattctgg agaggaagtt
    77641 tcaaaagggt atgaaaaaat aaatgctaat gaatttattt ttcaattact tttagatagt
    77701 tcatatacat tggaggagaa aggatttcat ataacaatag aaaatgaact ttataaccaa
    77761 tatcatattt atgtagatgt tacacaattt agaaggatat ttgataattt atgttctaat
    77821 ataataaaat atgctaggaa agataagcct atagtatttt taattaaagt agaggattct
    77881 aaattactaa ttatacaaaa aaatagagta agtaattttt ctaagaatgt agaaagtttt
    77941 ggaattggta taaagaattg tgagaaaata gttgcatatc ataatggaag cataaatgta
    78001 aattcagatg ataaagaatt tgctattgaa atatctattc cagcaaaaga atcataaaaa
    78061 tttaaattat atattgtgta attgctatta tatattgtgt aattgcttat gtaaaattct
    78121 atgaagcagg aagcatgtga ctttagttat gggatgttca atattgtgta cctctaggca
    78181 agtaacaagt ttacttacaa gaccatataa tattattatc ttaaaaaaag gggacataat
    78241 aatatggttt tgacaggagc acattatatt tacattctat ttatggtaat tatattaatt
    78301 actatgatta tgaaaaagga tacaatagta ccatgtatat taggtgtttt ttttatggga
    78361 ttgttctttg aaaaaaacat ctttggtgct ataacagcag tgtttaactc ttttattata
    78421 tctttaaatg agttgggtcc aattatcttg attatagcta ttatggttgc attatctaaa
    78481 gccctagaag ccaataatgc tatacagtat atggtgagac cattttcgag agttataaaa
    78541 aattctaata cagcattttt tgtaactgga tttgttatgt tagttctttc ttggtttttc
    78601 tggccaactc cagctgttgc cttagttgga gctgtatttt tacctgttgc tatgagagct
    78661 gggctaccag caattggtgt tgcagtagca ttaaatttat ttggtcatgg tcttgccttg
    78721 tctacagact ttgttattca aggagctcca agtataacag ctggtgcagc aggtgttgca
    78781 gtatcatatg ttataaatga tggtatgatt ttgttttggg tgatgggaat cgtaaccata
    78841 tctatggcat tttatacatt aaaaagagat attaacaaag gaatgtttag agaagaacta
    78901 aaaggttttg aaagtgaaga agtagaagag ttcaatggaa aatctaaaat agcaactatt
    78961 ttagtagctc tgggatttct tgctgatata attgttatgt atatatttga cctaaaagga
    79021 ggagatgcat cagctctttt gggtggaaca gcagtatttt taataataat tataaatgtt
    79081 ataaattttg gcaaagatag tcttgaaaat gtatgtgaga atataattga tggttttgtg
    79141 tttgggataa aaatatttgg agcaattata ccaatagcag catttttcta tatgggtgaa
    79201 gttgcgccct tgacaggtgt atttggaaaa gtattagcac caggttcaca aggtttatta
    79261 tcagatatag gcatagctct ttctcaaaca ataccactta ataaatttgc cgtatcaggt
    79321 atagaaactg tagtgggggc aataactggg cttgatggtt ctggattttc tgggatttca
    79381 ttagttggtt cacttgcctc tgtatttgga actgctataa atgcaagtgt tggtgcatta
    79441 gctgcattag gacaaatcag tggtatatgg gtaggtggag gctgtctagt tccttggggt
    79501 cttatttcag cagcggcaat ttgtggggtt agtccaatag agttggcaaa gcgaaacttt
    79561 gtcccagtta taaccggatt ggttgtaaca accatagtag caatgtttat tatttaataa
    79621 atcgaataaa tctttaattg tacaaattaa aaatagatgt gtagctataa tttattataa
    79681 ttgttttact aattttaagc catacatcta tttttattga tatttttatt agtattcttt
    79741 aataaaataa tatttttcat tatactatac ataacatcta aatataacat ctaaaatact
    79801 gttatctatg tttaatatct tgccaaattt tttgatgttt tattaccctg tcccaccaac
    79861 atatataagc tatcgcaagt tttttaccta tactatcacc aaacaaaaat tttaatttta
    79921 atttattatt ttataatcta tattatatta actatattag tttgtagact ttagatgtaa
    79981 ttctaaatat taatactcca agagttcaaa ttcatatcct agttttcttg catttgatat
    80041 aaaatcattt aaaatttctg tactagtttt ggaaactgca tgtagtaaca agatagaacc
    80101 atcatgtaga ttatccatta ttttttgcgt tgcttcttca tgtgatggtt gtttatcagt
    80161 atcccagtct ctgtatgcaa aactccaaaa tacagtcttg tatcctaaat ttttagtcat
    80221 tgccaagctt ttttctgagt attttcccat aggaggtcta aaaaatttaa ccatatcttt
    80281 cccagttaca tctttatata acttttcaac atcatataat tcgtcattaa agttttttag
    80341 attgcttgtt tttgttggca tagatggatg ggttttacta tgatttccaa ctatatgtcc
    80401 ctcagaaacc attcttttta ctaaatcttt attttctttt atatatggag ctgtaacaaa
    80461 aaaaactgct ttaacctggt tttgttttag agtgtcgagt atctttgtag tgtatccatt
    80521 ttcataacct tcatcaaatg taagatatag tgttttttga ccatcttttg taggtccatt
    80581 gtatagggca tcatagtcag aaaatttaaa ttcaatgtcc gtatttactt ctggtgtttt
    80641 atgcttattg ttaggtatat aaaaccaatc aagagtagtg ttatctaaag aagatacatc
    80701 taatttatta ttatcattat tagtagtggc ttttgatggt ttatctgttc cgtctgaaac
    80761 tattacattg gaagtatcct taccaccatc tattttttcc ttatcttctt gtaactgtgt
    80821 ttccttattt tgattttcgt tttgattgtt ttgtgaattt gaacatccaa caataaaaaa
    80881 aatagaaata gaaagtagtg ttaaataatg caatactttt ctaaacattt tgaagctcct
    80941 ttctaaatta ataataattg catatagtat tattataatt ggaaattact attaataata
    81001 gttatatctt taaaaataaa gtcacaatag tatgacaaag ggtgaataat caataaattt
    81061 aaaaaaaaat gaaaaaaata gttgaccata ttatgagaag atgttattat aataaatgtg
    81121 ctcaacaaga agtaacaaaa taacaagcac aaagaagtta attgaat
//
LOCUS       DAMJYN010000006        73192 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.006, whole genome shotgun sequence.
ACCESSION   DAMJYN010000006 DAMJYN010000000
VERSION     DAMJYN010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 73192)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 73192)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..73192
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.006"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            249..2561
                     /locus_tag="PC466_000479"
     CDS             249..2561
                     /locus_tag="PC466_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HDF2767909.1"
                     /translation="MDIIKKLSHGCTLDCHDCCKFNVYTKENNVVKIEGDKNHPYTKG
                     FICKKGMAHLDRLNHKDRIKTPMLKVDGVWKEISFDKAIEIMAEKLTYYKEKYTSKSV
                     MHYDQYGSGSVLKYIGDIFFNFYGGVSRHKGGPCWSAGMHAQKYDFGVAKSHAIEDML
                     NSKSIFVWGKNPAYTTIHTMQIIKKAKEKGIKIVVIDPIYTKTAQIADKYVQVNPGTD
                     GALAIAMAKIIVEDKLYDEEYINSYVIGFEEYKKYLSSLELSFLIDECGVKENDIREL
                     VDLYTNKYSSINVGYGLQKYKNGGNTIRAIDALGAITGQIGFSGGGVNYANKVYPSVI
                     NSDPYNSQSYGEDREFYVSNISKFIEESLKNTSNKVNYASDELDTTSNKVNYISDELD
                     TTSNKVNYVSDELDTTSNKVNYVSDELGMALHKVNCVSDELDMTSNKVNYVLDELDIT
                     SNKTDYISNELYNLSNKSIKDNIPIKMAVITKSNMLNQLPDLVELERVFSKIKFKVCF
                     DMFMTDTATLCDMFIPCTNTLESEDIIYSSMTNPYITYNERAVKPAHKLMDEYYFFME
                     LAKKMGLNDYPFVEKRTYLEKVIEPLKRFDKNLDIEKLKNNYFTIHNLVAWEDKKFET
                     PSGKYELYSESIKNLGISPTPVYISNKYKEIEDKNISFRLLTNHHADTLFSQHFMDKK
                     SIAQAYINQRMAKKVGIEDKDIVILRSKKAKINVQINIDDGVGNYIVKMYVGWWKKHG
                     NPNSLTDTGISDFGGQVTYNESMVEIIRQN"
     gene            2649..2984
                     /gene="spoIIAA"
                     /locus_tag="PC466_000480"
     CDS             2649..2984
                     /gene="spoIIAA"
                     /locus_tag="PC466_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma F factor antagonist"
                     /protein_id="HDF2767910.1"
                     /translation="MVNYSLEHKNLYIEFMCSELDHHVANEIREEIDNLLSVNQVKNV
                     VFNFENINFMDSSGIGVIIGRYKKISNEGGRVSVINISSRVKKIFDLSGLNKIIGIYD
                     TYEEALSSL"
     gene            2998..3426
                     /locus_tag="PC466_000481"
     CDS             2998..3426
                     /locus_tag="PC466_000481"
                     /EC_number="2.7.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma F factor"
                     /protein_id="HDF2767911.1"
                     /translation="MNNIMEVKFSAISENESLARVIVASFAAKLDPTVDELVDIKTAV
                     SEAVTNAIIHGYEEDSSKFVFLRCEIEGNTIKIIVEDEGYGIENVEKAMEPLYTSKPE
                     LDRSGMGFTVMKSFMDDVEVSSVKDNGTRIEMTKKINVPK"
     gene            3449..4213
                     /gene="sigF"
                     /locus_tag="PC466_000482"
     CDS             3449..4213
                     /gene="sigF"
                     /locus_tag="PC466_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigF"
                     /protein_id="HDF2767912.1"
                     /translation="MEVTVAREEKKPLLSHEETLELIEKVQNGDEEAKEILISSNLGL
                     VRSVVSRFLNIGYDREDLFQLGSIGLIKSIYKFDPKFNVKFSTYAVPMILGEIKRYLR
                     DDGMIKVSRSLKQIAVKAKMESEALTKKLGREPSIEELAKAIDVEKEDLVMAMEANFN
                     VEYLQGVIHEEEGSPICLIDKISMKGESEEEKVVDNILLKDILGRLDKRERQIIVLRY
                     FEDMTQSEIGEMLNISQVQVSRIEKKVLSKLKEYIS"
     gene            4493..4930
                     /gene="spoVAC"
                     /locus_tag="PC466_000483"
     CDS             4493..4930
                     /gene="spoVAC"
                     /locus_tag="PC466_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein AC"
                     /protein_id="HDF2767913.1"
                     /translation="MDKNYKKYVDQISPKPTYLKNYTLAFIVGGIICMIGQAINDLYM
                     KVGGLDKLGASSATSITLIFIGAFLTGLGVYDLIGKRAGAGSIIPITGFANSIVSPAM
                     EYKREGYVLGVGANLFKIAGPVLVYGIGSSILCGIIYYIFKMF"
     gene            5084..6097
                     /gene="spoVAD"
                     /locus_tag="PC466_000484"
     CDS             5084..6097
                     /gene="spoVAD"
                     /locus_tag="PC466_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein AD"
                     /protein_id="HDF2767914.1"
                     /translation="MKNKRIGKRTVKLENKPTIISTGTIVGPKEGEGPLKDYFDMIMT
                     DDLYGEKTWELAESKMVETASQQAIQKAGKKLSDVNYMLGGDLINQIVPASFAARELA
                     IPFLGIYGACSTMAEGLCIGSMLIDGGFADLVLSGTSSHYCTAERQFRFPLELGNQKP
                     MTAQWTVTGAGSVLLAPNGDGPKVKYVTVGKVIDEGIDDGNNMGPAMAPAAIDTIYSY
                     FEDTNDDPNSFDIIATGDLGTLGKQIAEDFLKEKGVDISKVYTDCGIEMFNLKEQDVH
                     CGGSGCGCSATVFAGYIYDKLRKKEFNKVMLVSTGALLSPTSTLQKQTIPCVAHAVVI
                     VNE"
     gene            6111..6473
                     /gene="spoVAE"
                     /locus_tag="PC466_000485"
     CDS             6111..6473
                     /gene="spoVAE"
                     /locus_tag="PC466_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein AE"
                     /protein_id="HDF2767915.1"
                     /translation="MLMDYVRVFIVGGIICLIAQVMMDYFKMQTPYVMVTYVTTGVVL
                     TFLGLYEPLVKFAAAGATVPIIGFGYSLATGVIKSIQSDGFLGIFLGGTTATAGGIAA
                     AIFFGYIMSVVFTPKAKP"
     gene            6656..7672
                     /locus_tag="PC466_000486"
     CDS             6656..7672
                     /locus_tag="PC466_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDF2767916.1"
                     /translation="MVTIKDIARNLGISYSTVSRCLNNNPNVSEKTKKKVVEEANRLG
                     FHFNVNARNLAKKETNRIGVIFSNNFNHQDTRKFFSDIMDSSINSIETNKYDFIIQPN
                     NNISGDSNVYKMVNGQMVDGLVIVSQSIKKEEYDFLKDNNFPHVFIYFKPSFVGEVDN
                     FFWDDNVYGGYIATKHLIDHGHKDIITVTSDDRSSKMHEDRTKGYLNAMEEANLKTEV
                     IKSKMDFESQVEFLEKYIDKIKKASAIFVQQDVPAISIIQELKTTYGINVPEDISIIG
                     YNNIELISYFRSHLSTIDDPREQVIKNGVDSLVNIINKKSTEHIPRKLYPRLIIRNSV
                     KRIK"
     gene            8047..8889
                     /locus_tag="PC466_000487"
     CDS             8047..8889
                     /locus_tag="PC466_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3100 domain-containing protein"
                     /protein_id="HDF2767917.1"
                     /translation="MKEKAGIRNAIIAAFIITILAELIGPISFKVMGINVTLLSILWA
                     IFIGMAVSPHLLGRVIPALKKFIGDNEINVSPYLLSLTLYPLGIMFGINAGPKVGILL
                     QAGPALLLQEFGHMGTMLIALPVGVALGLGRSALGGTFSLCRDTALGIIGDKYGLNSP
                     EGIGTLGTYISGSIFGTLLFSFLAPVGVLLGFHPYALAMASGMGSGSMMGAATASLMN
                     TVPQMSEQILAYSATSGLITAVTGIYIELFLSLPVANYYYSKVAPVIERFRGRKTRRT
                     SNKL"
     gene            8904..9368
                     /locus_tag="PC466_000488"
     CDS             8904..9368
                     /locus_tag="PC466_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2767918.1"
                     /translation="MEKTFKTIMEQIKIVLFIYIITCFGQMIALKTQAQDLLIGSISG
                     FLLVIIAIIIKNFVKKPNLPGFAWATLVAFVLSLPISPVGDIIATNVGKINFMSTVTP
                     LLAFAGISVGNQLDILKTLSWKLVVISFIVMTSTYFGSAFISQTVLRLNGML"
     gene            9355..10527
                     /locus_tag="PC466_000489"
     CDS             9355..10527
                     /locus_tag="PC466_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HDF2767919.1"
                     /translation="MECFKEVVNMNELKAKIKEEIKLLSEEKKTSFEKVSDYLFSNPE
                     LAFEEYKSQKALCDLLEENEFNVTKGVGGLETSFEAVYSNGTNGKTVAFLAEYDALPG
                     MGHACGHNIIGTSSVGAGIILKEIMKKHNIEGTVKVFGTPAEERVGGKITMIKEGVFN
                     NVDAALILHPSDASMPDDISFAQVNLKFDFTGKASHAAAFPWEGKSALSGVIALFNSV
                     NSMRLHLKDYARVHGIITDGGSIHNIIPEKSTAIFNVRALSIEYLNEICEMLKNCAKG
                     AAISTGTNVEIVQLDEIYKEIKNDSELVNIVRQNFEVLGEDYVERDLSQGIGSTDTGN
                     LTHEIPAIQAYIKLKENTATHTDEFAVAAGGEEGKVALIKAIKVLAMCGVDILYSK"
     gene            10571..11506
                     /locus_tag="PC466_000490"
     CDS             10571..11506
                     /locus_tag="PC466_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1177 domain-containing protein"
                     /protein_id="HDF2767920.1"
                     /translation="MILKQVIEVYDILDKANANGEEVKTYLQGYGEVDVTVKELSSSK
                     GSTDLVKLTIPGKNGKLKGGDAPTLGILGRLGGIGARPEVIGFVSDGDGALVAIAVAA
                     KLLDMQRKGDILDGDVVISTHICPDAPTKEHYPTPFMDSPIDMMTMNENEVDSSCDAI
                     LSIDTTKGNRVINTRGFAISPTVKEGYILKTSDNLLDIMQTVTGKSPFVFPLSIQDIT
                     PYGNNLYHLNSILQPAVATDAPIVGVAITTEMPVAGCATGATNFSDLDSAGRFAIEVA
                     KLFGRNKCDFYDKEEWEMLIKRYGKLNRFQTFGIQ"
     gene            complement(12305..12703)
                     /locus_tag="PC466_000491"
     CDS             complement(12305..12703)
                     /locus_tag="PC466_000491"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HDF2767921.1"
                     /translation="MKWKELYNNARGKLNPRTISPFIDAGGVAAAILTDSGNVYTGVC
                     IDTACTLGMCAERNAIANMITNGESKITKLVCVMSNGSVGSPCGACREYLMQLDKDSA
                     CIEILVNVETEKTVKLSELLPDWWGSDRFI"
     gene            complement(13002..15653)
                     /locus_tag="PC466_000492"
     CDS             complement(13002..15653)
                     /locus_tag="PC466_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase domain-containing protein"
                     /protein_id="HDF2767922.1"
                     /translation="MNNDNDKNGNKIRRKKVSSSGNTNKPINRTSANKTRSTKNKKKS
                     KKSDKFKKLRVFGIVFLVLLVVGTAGTAGLVFASLRDVTPVTEAVLDKQTNQTTTIKY
                     ANGKTLSTAPSVNKKTPVPLDKISPYLQHAVIAIEDERFYEHKGVDIKGLFRSVLKTL
                     TGTKQGGSTIPMQVSKMLLTTEQQTIPRKIKDIYYAHEMSKTVSKDKILETYLNNFFV
                     GRGLAGAEAGARGYFDKSAADLTLAESALLAGSTKNPSRFSAYKTSKLEGNETKEDLE
                     NKLLFFVNTTDDDLDDPTQVDFDMIEKIKSWELISNDTYRQLKAGTLVVRKAVSNPEA
                     KKRQEIVLKKMLELKYIKQSEYDEAIKAKIEIKLPQSSDKVSSSVEDLIESEVINALM
                     EQGHTNDEAQNLFYNGGLIVNTTIDPKMQDALEEEFDRNSNFPGHMVGPDGVSQPQAA
                     MVILDYKNGEIRALAGGRNISGRKTLNRATNPHQPGSSIKPLAIYTPAIDTLKITQST
                     ALSDSRGGYKFEENNKWNPRTTTAGHGSMSLRKALAKSSNTIAVKTAEMLGDSYDECV
                     DIMMDYLKNFGITTLKNNHSGSSEASDRKFPSLTLGGMANGITPLQMAAAYGTLANQG
                     VYVEPSIFTTITTFDGQLLVKNAPEEHKVVDPEVAYVVTDMLESVITEGTGGVATLPK
                     GMPVAGKTGTTNSAYDAWFVGYTPYYVGATYIGDDAGRKDDSGNTIKRREVPHGSTST
                     AKLWEKIMEKIHANLTVTEFEVPKNVYFTKINLEDGGKQSSGSKAAFIEGTAPTKVSS
                     QPSSEDTKKPDNNQPEENNNNNNNTGDNGGGSTPPDNGGNNGGGSTTPPDNGGNNGGG
                     STTPPDNGGNNGGGSTTPPDGGGTPAT"
     gene            15867..16565
                     /gene="yunB"
                     /locus_tag="PC466_000493"
     CDS             15867..16565
                     /gene="yunB"
                     /locus_tag="PC466_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein YunB"
                     /protein_id="HDF2767923.1"
                     /translation="MNRIVDRKTKNEFRKIIAIFLVILFLSVFIGSFIYIDKTLRPTI
                     TVLAETKALELANRSINKAVAEMVEGKINYEDLMDIQLDNNGKITMIQANTIMMNEIA
                     SAIALEIQDELKKDKTASSYIPIGTALGSPILAKYGPKLEVSIEPIGTVSVNFKTEFE
                     SSGINQTRHRIYLEAQTQVKVVIPLITSTKQIKAQIPICETIIVGDVPESYVNIPEKN
                     LGNVLPNTGKNTNK"
     gene            complement(16777..17784)
                     /locus_tag="PC466_000494"
     CDS             complement(16777..17784)
                     /locus_tag="PC466_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S55"
                     /protein_id="HDF2767924.1"
                     /translation="MQLKNFHFKNNTLSKKTNLAKSKFTIVLTFLFLLYFFSNNLIYA
                     QNLQKNEPEYLIPIGNVLQIDAELKNIIVRNPGEASPFRLGDAIVKVNNSEVDGYSDF
                     ANTLNALPEEKQVSILLNRGGQLITMKTTKHILEKISFNNLLSGFATLTYINPDTSEF
                     GAVGHPISVGNARKIPIKTGSISTTKHLNIEKSYKGSVGCINAKRENIIGSFTENTDF
                     GIRGQINNFDISNLKKYKVASLDEVKLGKAQIILQDNFNKCKKYNIEIIDIENQKHPE
                     SKSFKIKITDKKLLAQTGGIVQGMSGTPIVQDNKIIGAVSHAIENDPAVGYGVFIKWM
                     L"
     gene            18012..18896
                     /locus_tag="PC466_000495"
     CDS             18012..18896
                     /locus_tag="PC466_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDF2767925.1"
                     /translation="MKKYRLLVTCIIAMGIIIIGTSNPVSNFYKTTNLISSGNITNEK
                     ADKDENSNKNNKDKNEDKSNSKSNKDKSSEDKSSDKKNKIQKNKKLLICIDPGHQGKG
                     DSNLEPVAPGSSSKKARVSSGTEGIATKKPEYVLNLEASLVLKSILESKGYNVIMTRE
                     THDVNISNSERAILANDKKADMVVRIHADSLNNSSKTGASILIPEKDGKYTAPIYEES
                     NKCAEFIKQNMEQSGIQINGIVQRGDLTGFNWSKVPAVLVEMGFMSNYNEDQMMSNPD
                     YQRKMMQCIADGLDAYFK"
     gene            19098..20648
                     /locus_tag="PC466_000496"
     CDS             19098..20648
                     /locus_tag="PC466_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018592108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HDF2767926.1"
                     /translation="MLVVENVSHGFGARTILENVSFRLRKGEHIALVGANGEGKSSFL
                     NIITKKLMPDAGNIKWSSRATVGYLDQHTVLSKEKTIREVLREAFKHMFDLEQEMIAM
                     YDKMGEASDDEMSKLLEETAEIQTILENSGFYMIDAKIQEVANGLGLGEIGLDKDVTD
                     LSGGQRTKVLLTKLLLENPTILILDEPTNYLDEEHITWLTKYLQEYENSFVLVSHDIE
                     FINNTCNVIYHMENGELNRYKGNYDEFVRLNDIKKRQEEQAYDKQVEERKRLEDFVAR
                     NKARVATRGMANSRQKQLDKMEILERPKEKIKPTFAFKDARAASKIIFETENLVLGYD
                     EALTKPLNFHLERGKKIALKGMNGIGKSTLLKTLLGIIKPFEGNVKLGDYLEVGYFEQ
                     ESSRENSNTPMDEVWSEFPGLTNFEVRQALAKCGLTNEHITSQMRVLSGGEAAKVRLC
                     KVMLKNINFLVLDEPTNHLDVEAKDELKKAIKEFKGTVLLVCHEPEFYSEIVDDVWNI
                     EDFTTKIV"
     gene            20677..21138
                     /locus_tag="PC466_000497"
                     /pseudo
     CDS             20677..21138
                     /locus_tag="PC466_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888584.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
     gene            complement(21317..21556)
                     /locus_tag="PC466_000498"
     CDS             complement(21317..21556)
                     /locus_tag="PC466_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004609551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2767927.1"
                     /translation="MSKDYGYPSFELICKASSGDEMAVKEILKFYDGYISKLCLRPFY
                     HSESGKIIMQVDEELKGEIHTDMMKAILKFEIGVK"
     gene            complement(21561..21980)
                     /locus_tag="PC466_000499"
     CDS             complement(21561..21980)
                     /locus_tag="PC466_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009588541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDF2767928.1"
                     /translation="MRTSSFEHIVRLQFNSLMLIVIKNKVKSRNRQLARHSKREVLFC
                     EIAETKQVERGTIDTCFYDCVSFKVLHFTIYVSDETLGTVLHRLSEKQRSAILLRYFQ
                     GMNDRKISELYHVSRSAICSRRTRGLRKLKMLLSEGK"
     gene            complement(22207..22536)
                     /locus_tag="PC466_000500"
     CDS             complement(22207..22536)
                     /locus_tag="PC466_000500"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2767929.1"
                     /translation="MGISLFLELPAIVSYWVVTVMCFVAMGVSTMFVVQIYTLVQTQT
                     PPQLVGKIMATLVAVAMCGQPIGQMVYGILFDVFIQETWVVMFVASIASIMISIYSKR
                     IFQKLEI"
     gene            complement(22539..22838)
                     /locus_tag="PC466_000501"
                     /pseudo
     CDS             complement(22539..22838)
                     /locus_tag="PC466_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
     gene            23343..23696
                     /locus_tag="PC466_000502"
     CDS             23343..23696
                     /locus_tag="PC466_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2767930.1"
                     /translation="MRKKEDKYDFRAFGLAIKEARLKRGLTREQVGALIEIDPRYLTN
                     IENKGQHPSIQVLYDLVSLLHVSVDEFFLPANNLVKSTRRLQIEKYMDSFTDKELSLM
                     ESLASGINEARNIED"
     gene            complement(23756..23923)
                     /locus_tag="PC466_000503"
     CDS             complement(23756..23923)
                     /locus_tag="PC466_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HDF2767931.1"
                     /translation="MCPVCGNKTRLKIREDTELKKFPLYCPKCRQENLIEIKQFKVTV
                     ITEPDAKTQSR"
     gene            complement(24042..25961)
                     /gene="tet(M)"
                     /locus_tag="PC466_000504"
     CDS             complement(24042..25961)
                     /gene="tet(M)"
                     /locus_tag="PC466_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HDF2767932.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYTSGKLLEALELEQEESIRFHNCSLFPVYH
                     GSAKNNIGIDNLIEVITNKFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLH
                     LRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRKKIENPHPLLQTTVEPSKPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLG
                     KVQMEVISALLQEKYHVEIEIKEPTVIYMERPLKKAEYTIHIEVPPNPFWASIGLSVA
                     QLPLGSGVQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            complement(25977..26093)
                     /locus_tag="PC466_000505"
     CDS             complement(25977..26093)
                     /locus_tag="PC466_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HDF2767933.1"
                     /translation="MILKYPENICMLCMPMVMHKNPSDKSIYHWDFYALLGF"
     gene            complement(26569..27204)
                     /locus_tag="PC466_000506"
     CDS             complement(26569..27204)
                     /locus_tag="PC466_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2767934.1"
                     /translation="MEGYAMKISHLGNNIQTIRKFRGMKQQELADKIGINMQSLSKIE
                     RGLNYPAYETLEKIMEVLDVTPNELLSGEWKYVNQSEKEVCQFLRAEERLNAELKHGH
                     YDNFFDSEEEWLEYELEKLREYITDYINGKSIEASDLYPIKEFIQHLKFQKLLDRYDD
                     LYSMDMFGESIEGHKYKTPYQVVKMINPNSKEDMELLREVLRNNNFDDEDE"
     gene            27716..28858
                     /locus_tag="PC466_000507"
     CDS             27716..28858
                     /locus_tag="PC466_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HDF2767935.1"
                     /translation="MNNLEFALEMKNKRLASGLSQGELASLTHVSRYSINRFENGKAN
                     ASKETQNIILRCLNYYICDKPFYLLVDYLSVRFPTTDALEIIRKVLGMKADYFIHYDY
                     GYYGYKEHYAYGEIKVMASDDEHMGVFLELKGAGSRNMEYVLQAQNRDWYSFLNRCLD
                     CGGVIRRFDLAINDMCGLLDIPVLSEKYKNGGADCRCKNYENVQGGKLSGKNRNLAST
                     LYIGSKASTKYFCLYEKQKEQATKKKHTDIINRFEIRLRDKKAVQAVEELLLTYNPHG
                     LVFYLITDFVQFPDYPLWEIFISHDSLPFEMNPVPVNMERTLQWLERQVMPSIVMIEE
                     IDRLTGSNYMKMIDECTHLSEKQEMLVEQMCTDIADVIESEGVFYE"
     gene            28851..29057
                     /locus_tag="PC466_000508"
     CDS             28851..29057
                     /locus_tag="PC466_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HDF2767936.1"
                     /translation="MSNAQDIPVWEKYTLTIEEASKYFRIGENKLRRLAEENKDAGWL
                     IMNGNRIQIKRRQFEQVIDKLDAI"
     gene            29136..30329
                     /locus_tag="PC466_000509"
     CDS             29136..30329
                     /locus_tag="PC466_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDF2767937.1"
                     /translation="MKEKRRDNKGRILHTGESQRTDGKYLYKYVDAFGNTKYVYAWRL
                     TPTDPTPKGKREKTSLRELEQQIRRDIEDGIDSTGKKMTLCQLYAKQNEQRANVKKST
                     MKQREQLMRLLKEDKLGARSIDTIKPSDAKEWALRMKEKGFSYNTINNHKRSLKASFY
                     IAIQDDCVRKNPFDFKLSEVLENDTKEKVALTEEQEQALLSFIKTDNVYHKYYDDVLI
                     LLKTGLRISELCGLTVADIDFKNEVVIIDHQLLKSKEQGYYIETPKTKNGTRQVPLSR
                     ETIQAFQRVMKKRPKAEPFVIDGRSNFLFVNHKGKPKVAIDYNALFVRMVKKYNKQHK
                     DNPLPHITPHTLRHTFCTRLASKNMNPKDLQYIMGHSNISITMNWYAHASIDTAKSEV
                     QRLIA"
     gene            30472..30678
                     /locus_tag="PC466_000510"
                     /pseudo
     CDS             30472..30678
                     /locus_tag="PC466_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888584.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1461 domain-containing protein"
     gene            complement(30789..31049)
                     /locus_tag="PC466_000511"
     CDS             complement(30789..31049)
                     /locus_tag="PC466_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich small domain-containing protein"
                     /protein_id="HDF2767938.1"
                     /translation="MGENYKFFNHKDCEFFPCHKTNKPEEFNCLFCYCPLYALGENCG
                     GNFKYTDKGIKDCSSCMLPHKKDNYNYIMGKFQDLVKITSKK"
     gene            31266..32549
                     /gene="hflX"
                     /locus_tag="PC466_000512"
     CDS             31266..32549
                     /gene="hflX"
                     /locus_tag="PC466_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HDF2767939.1"
                     /translation="MKEIQEKALLVGLNLTTIVKKNDDIDTSESMEELKELTKAAGAE
                     VVGSLIQNKHSVDAAYYIGKGKVEEIRAYSDSLDATLVIFNDELSGAQIRNIENVVGR
                     KVIDRTTLILDIFAQRALSKEGKLQVELAQLKYRLPRLYGMGGEMSRTGAGIGTRGPG
                     EQKLEIDKRHILNKAADIRRELKEVKKNRETQRVKRLKSNIPIVALVGYTNAGKSTLL
                     NELIKTHKDYEQEKEVFVKDMLFATLDVTLRKALLPNKKEFLVVDTVGFVSKLPHDLV
                     EAFKATLEEVQYADLILHVIDATNTSYELQKSTTEGVLKELGVNDKKHILVYNKVDKL
                     ELDIYPKSQEDIVYISAKQGINMDKLLNMIEIALMENTYSVSLMLPYERGDIFSRIKD
                     KYNVENFEYGENGITLDVNFDEEDFNIYREYILEK"
     gene            32557..33234
                     /locus_tag="PC466_000513"
     CDS             32557..33234
                     /locus_tag="PC466_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HEAT repeat domain-containing protein"
                     /protein_id="HDF2767940.1"
                     /translation="MDINWENIDNLEDYFITYLLYKESKTVSQISKIRNISSTEAGEQ
                     LIQAKLKIKEMQKDDFEASKDILDKFLELDKIKRLDFMDSLDDEKMVYFKRKVFKRIL
                     VEKNAEDLIVLIWATGELKDDRFLKLLHQLTNHRHSDIRRITYSAIRKIESPSSREVL
                     QKGLYDKNAQTRQYCAKALSKLGDENSLKILQQLKDKNKNFEKEYVLRAYDEAIKSLE
                     NAKNLKK"
     gene            33320..33763
                     /locus_tag="PC466_000514"
     CDS             33320..33763
                     /locus_tag="PC466_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HDF2767941.1"
                     /translation="MIVRRCAGGVVFYANKVLIVKNDRGEWTLPKGKILGGGLPYESA
                     VQRVKVETGIDAKMIDVAGDTMYEFFSRSRQQEVCNAIMWYVMEACNTNCVLAPEFQE
                     GGFYKVKDALDMLSHHKEQALVEVSYKKFKELKKLVSEGDDVPAN"
     gene            34069..34713
                     /locus_tag="PC466_000515"
     CDS             34069..34713
                     /locus_tag="PC466_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HDF2767942.1"
                     /translation="MSNYRTLHEFGTDEITIEKSVFIGYAKPIKSEEEALEFINEIKK
                     KHKDATHNVWAYTVGKNMNIQRYSDDGEPQGTAGIPTLEVIKKEDLRDVVVVVTRYFG
                     GTKLGAGGLVRAYTKGAKLGLEAGKIIYKVMYQEVKVKIDYTQLGKVQNELMNLGYFI
                     KDTVYEDNVEIVVYSRLEDVEKLSEKMIDITNGTGKIILGEEFYLSEQNGEILI"
     gene            complement(34799..35176)
                     /locus_tag="PC466_000516"
     CDS             complement(34799..35176)
                     /locus_tag="PC466_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HDF2767943.1"
                     /translation="MLFALIGFFAGIIGGMGMGGGTILIPALVLLAGIDTKIAQSVNL
                     LSSIPMTLIALAIHIKNKNVIFKLVIPIAVFGVLGAVFGSLLANYLSSDILKKIFGIF
                     LLLVGLFEVKKGFCAKSDKKPLN"
     gene            complement(35176..35562)
                     /locus_tag="PC466_000517"
     CDS             complement(35176..35562)
                     /locus_tag="PC466_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HDF2767944.1"
                     /translation="MKKTDDLKKKYFDFNLKNTIIGVFTGFINGVFGSGGGTLLVPIL
                     NDIVKVEEHKSHATALSIIIFLTTASSVLYVSKGTYDVNLTIKVAVGSILGGIIGAKL
                     LNKVTGKFLRISFGIIMIIAALRMVF"
     gene            35741..36496
                     /gene="nadE"
                     /locus_tag="PC466_000518"
     CDS             35741..36496
                     /gene="nadE"
                     /locus_tag="PC466_000518"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+) synthase"
                     /protein_id="HDF2767945.1"
                     /translation="MSNIKIQIDKTVEWLINKVNEANAKGLIVGVSGGIDSAVVANLI
                     KKAFPENSMGVIMSIKSNPQDREDALKVIEGCDIEYLDLDLIEPQSAILDMVVGNLKD
                     KHLYRAEYLKMTDANLRARVRMSTIYTIANNLGYLVVGTDNAAEIHTGYFTKFGDGGV
                     DILPIANLTKGEVYEWAKELGVHEDLINKAPSAGLWEGQTDEDEMGTTYNMIDAVLEG
                     RLDEVPKRDQEIIERLHRLSEHKRKTPAQPPKF"
     gene            36579..37298
                     /locus_tag="PC466_000519"
     CDS             36579..37298
                     /locus_tag="PC466_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDF2767946.1"
                     /translation="MGRIGNIINRKGKQDAQRAKIFTKHARAIAVAAKEGGADPEYNA
                     ALKTAIEKAKADNMPNDNIDRAIAKGAGAGAGEDYETIVYEGYGPGGVAVIVETLTDN
                     KNRTAGNVRYYFDKNGGNLGTSGCVSFMFDKKGQILVGLGDGVSEEELMDVALEAGAE
                     DFITEEDGYEIITTPEDFSSVRDELKAKGYEFISADVKMIPQTTTVLTEESHLKMMNK
                     LVDMLEEDDDVQDIYHNWEVE"
     gene            complement(37466..38470)
                     /locus_tag="PC466_000520"
     CDS             complement(37466..38470)
                     /locus_tag="PC466_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HDF2767947.1"
                     /translation="MATIKDIAKDCGLSSATVSYVLSGKGNERRIPLHTQELILNSAD
                     KLGYKRSTPIKHNNIKIAFYWQDEGFELASTNILQAINHIISLEHLNINIIIRPYKVG
                     HLCDDEYFFANNYYDGIVLTGINADDIEYLVKNKPKIPVVVVNREIPGFSSVSIDNEE
                     TGRIAALHAIQNGKNDIAVVFNPTSFTCMTLRGKSFLKTCKEHGIHLSDSIYYCSNKI
                     DSGYDIAQKMLAKNSLKKVIFCNHDVVALGMMNAFHESGIVIGEDIQIFAASNGPSRL
                     MARSIPPLTVIDLKMEETAERSLRMIIDTVTGRINGIQQQVIYPSIIYRQSSPAQNLL
                     "
     gene            38736..39632
                     /locus_tag="PC466_000521"
     CDS             38736..39632
                     /locus_tag="PC466_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA lyase"
                     /protein_id="HDF2767948.1"
                     /translation="MSKVNIFEVGPRDGFQNLKEFLETDKKLKIIDGLIASGIKQLEI
                     SSFVSPKAIPQMKDAKEVATYCVEKYPDVKLYALVPNLYGAKVAWECGIRDISYVISL
                     SETHNKKNINRTHEESIDELKKIMNTYPDMNICIGMATVFGCPFEGLPKIEDAIRFAK
                     RLWENGIREINLADTIGIADPKQVRETISALVEALPECRWQVHIHDTRNMGMVNTLVA
                     IESGITTVQSTLGGLGGCPFAPGASGNTATEDLVYMLERMGYDTGVDFVKLLELSKYQ
                     KSFVNGVYSGHHVNIKSDSCNC"
     gene            39770..41032
                     /locus_tag="PC466_000522"
     CDS             39770..41032
                     /locus_tag="PC466_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2767949.1"
                     /translation="MDIIALLLFLGVIIIAFVRKNNAGILALAIGVIAVRIFGMDDKE
                     LYGAISNSMFTTLVGITLLFAIVNSTGALKLVAEKIVAASGKRVWLIPIAVFIAGFVV
                     AGVGPGAIPALAIIPAMAVPVAITVGYNPVMLALIGECGLMAGRMTPITPEGQIITTV
                     AEGVGIENVMPTILACQTLSTIVFSIVLFIIFKGYKLKKPINVIDSKQIEKFNIKQII
                     SLISIVVMIAFIIIFDMNVGLAAFAVSAVLIFFNIADEGECIKSIPWSTIVMVLGVGA
                     MMTIVDAAGGIDLMSNALSSLMNSKTATPIMSISAGLMSMVSSALAVVYPTMMPMCVD
                     IAKAVGGVDPLALIAAVGVGGSLAGVSPLSTGGALILAAMGSSKKDFNKEEQNKVFVQ
                     LFIMSAVGLLVIAVVSILSFNAITHLMN"
     gene            41108..42301
                     /locus_tag="PC466_000523"
     CDS             41108..42301
                     /locus_tag="PC466_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase"
                     /protein_id="HDF2767950.1"
                     /translation="MKKGALSNIKVLDLTRVLAGPYCTMMLADFGADVIKIEMPRKGD
                     DTRGFGPFVNGESLYYANINRNKKGITLNLKSEEGKNIFLEMVKHADVVVENYRPGVM
                     EKLGLGYDELAKVNNQIIYGAVSGFGCYGPYSERPGYDIIAQAMGGLMSITGQEGGEP
                     TRVGNAMGDVLGGMNLTIGILTALNARKIIGKGQRVDVSLVDSVVSSLETGIQRYFDS
                     GQPELMGNRYASAYPYDSFKASDGSFVIGCGNDKLFEKLCKKVLFREDLLIDERFKTN
                     LKRCEHYKALKPEIEKWSVKHTIKEAVDLISEAGVPAAPIYNLDCVTTDEHIAKAREM
                     IVDISHPIIGNMKVNGNPVKLMTTKAKIDMPAPSLGESNEEIYNGWLGFDSDKIKDLK
                     ENGVI"
     gene            42930..43724
                     /locus_tag="PC466_000524"
     CDS             42930..43724
                     /locus_tag="PC466_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="HDF2767951.1"
                     /translation="MESVMENLNNLKVEVKDKVCVITINRPKALNALNSDTLRELSQV
                     IDVVSENEAILGVIITGEGKVFVAGADIRQMQNYKSEEGRKYAGYAQGIFDKIEALEK
                     TVIAAVNGYALGGGCELAMSCDIRIASEKAIFGQPEVNLGVIPCFGGTQRLSRLVGTG
                     IAKELIFTGRQVNAEEAKSIGLINKVVPSDLLLEESMKMMNQIVEKAPIAIRYAKVVI
                     NKGIDMDLKNALELEKDIAGLTFATRDKQEGMNAFIEKRKPVFENK"
     gene            43818..45158
                     /locus_tag="PC466_000525"
     CDS             43818..45158
                     /locus_tag="PC466_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HDF2767952.1"
                     /translation="MNTGVIISLVGIIIALSLLVVMVMKGINIFIIAIVCSSLVAITG
                     SLNVYDALKVDYMTGFVGFLQANFFIFLTGTLMGKIMEITGGAKSIAKMIVRWIGKDK
                     ALLSIPIACGILAYGGVSVFVVSFAVFPIALEIFKEADLPRRFIPAALTFGCSTFAMV
                     APGAPQIQNIVPASTLGTDIMAGAVNGFISCAVMFIVGSTILYKMVSKEKANGGHFIA
                     HESDIFDEAEATNSKRENGPNGVIALIPLIVSILIINVKVNGKAIVPIEVGVFIGALL
                     VYLLLNKYQDNTKIVGHVGDACKTTVVAICNTCAVVAFGSVVKSAVGFDFIVNAMTNI
                     PGPPIAGAAVGTTVIAGICGSASGGLGIAAPLLGPVFLAKGVSAAALTRTMAISSAAL
                     DSLPHNGYIVTVTNGLCKETHKDAYMPIFWVTVLTPFIGTIVAVLLFTMFPGLP"
     gene            45295..46527
                     /locus_tag="PC466_000526"
     CDS             45295..46527
                     /locus_tag="PC466_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase"
                     /protein_id="HDF2767953.1"
                     /translation="MLNKPLEGVKVIDLTYFVAGPGTSKILADWGADVIKVEPSFGDP
                     GRKTGATMTMPIDDYNNPFYSTYNSNKRGLSINLKSETGIEIMDKLLSEANVFVSSYR
                     TGALKRLGLDYESLSKKHPHLIWGQINGFGDFGPAKDNAGFDTVAFWARSGAMLDIAE
                     KDTSPINPPIAFGDATTSCSLSGGICAALYQQAKTGKGQKVMASLFGQAIWNASSLLA
                     STQFSDEYPKTRKNAISPVINSYRCKDGKWIFLSILEHERYFEALCRLFGREDLIKEE
                     KFASSVESKKNATELINILDGEFAKFTQNEMVEKLTAADIAHEKIQHVNDVVTDEQAI
                     ANNYIYEHTSKNGNKTMLASTPVKFGNIEVNMTCDAPLIGEHSDEILRELGYSDSDIE
                     ALIESGIVTMNKEACEIC"
     gene            46567..47709
                     /locus_tag="PC466_000527"
     CDS             46567..47709
                     /locus_tag="PC466_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="HDF2767954.1"
                     /translation="MDFRLTEAQLMLQRVAKEFAENEIAPIAAETDKTGIFPRELFSK
                     MAKIGFNGIGTPVEYSGSGGTDIEKVIVVTEIAKKCAASAAILSIHTIYAQAILKFGT
                     EEQKKKYLPMMAEGGCVGAFALTEPNAGSDAARAATTAIIDEETDEYVLNGTKCFISG
                     GGQAESLIIFALTDPSKGIKGMSAIIVDKGTPGFSIGKIEEKMGIHGSETAELIFDNC
                     RVPKSNLLGKEGKGFNIAMTCLDGARIGIGAQAVGIAEGALEESIKYSKERVQFGKPI
                     SALQGIQWYIADMATMVESAKLLVYYAADLKARGEKHTKEAAMAKYNASSTAREVTNL
                     ALQIHGGYGYMKDYPLERMYRDAKITEIYEGTSEIHKVVISRAVLG"
     gene            47720..48514
                     /locus_tag="PC466_000528"
     CDS             47720..48514
                     /locus_tag="PC466_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HDF2767955.1"
                     /translation="MNIVVCLKQVPDTNEVKINKETGTLIRDGVPSIINPDDRNALEE
                     ALKMKDELGAVIKVISMGPPQAKSALKEALAMGADEAYLISDRAFGGSDTWATSTIIA
                     AAIEKVGKYDVIFCGRQAIDGDTAQVGPEVAEFLGIPQVTYAKEVKVQDDKLLVTRYT
                     ETGDYLIEAKMPVLLTAIKELNNPRYPSVKGILEAYNNGDAKITVLTLADLDVDTTQI
                     GLKGSPTNVYKSFAPVKDKHNEIIEGINKKEKAEKLIEILFDLKLV"
     gene            48525..49547
                     /locus_tag="PC466_000529"
     CDS             48525..49547
                     /locus_tag="PC466_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HDF2767956.1"
                     /translation="MMRAKVNQGINLNDYNGVWVIGEQREGKINPVTIELIGEGRKLA
                     DQLGKELEVVIAGYEVEKEVKELLHYSVDKVYYINDPLLKDFTTDGYAISIANLIERK
                     KPEVVLVGATSIGRDIAPRIAGKVGTGLTADCTKLEIDSTDNKLLQTRPAFGGNLMAT
                     IVCPKNRPQMSTVRPGVMAKAVRNESETGILEVVTPELTEKMIRTRLVEVLPQEKKSV
                     NLTDARIIVSGGRGLKRAEGFELIKELADKLGAEIGASRAAVDSGWIEHSHQVGQTGT
                     TVRPELYIACGISGAIQHLAGMSDSKYIVAINKDAKAPIFSICDYGIVGDLYEIIPEM
                     IESLNR"
     gene            49646..51022
                     /locus_tag="PC466_000530"
     CDS             49646..51022
                     /locus_tag="PC466_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent Fis family transcriptional
                     regulator"
                     /protein_id="HDF2767957.1"
                     /translation="MKEQWYKDIFARILSMTDDGFIVVNTSGVIIDINDKYCDFLGKE
                     RKDIIGQNIQSIIPNTKMLDVMKDKYCEEGAIHHYSGGNTKEKSVIVSRSYVENDNGE
                     VVAGVAQVKFRLQSFDVAKKLMSEYMELQYYKEQFKDNCGFDKLIGENRDFIELKKTG
                     VKASKTNFPVLLTGETGTGKEVFARAIHNNSSRSDKPMVSINCAAIPEELLESELFGY
                     DEGAFTGAKKGGKKGKFLVANNGTIFLDEIGDMPLTMQAKLLRVLQESEIEPVGGLKT
                     IKIDVRVISATRKNLSKMVEEGLFREDLYYRLNVINIHMMELKDRQDDILLLANYILN
                     KLNVEYKELKVLSDKVKNCFINYTWPGNIRELQNVIKSAYAVSDDMVIMMCDLPSKMD
                     NISRVAQCNVDSNCSIHEMVENYEKSLIIDVLRKYNWKCSKAAEVMGIHKSLLYKKIK
                     KYEIELNN"
     gene            complement(51354..51698)
                     /locus_tag="PC466_000531"
     CDS             complement(51354..51698)
                     /locus_tag="PC466_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2767958.1"
                     /translation="MDQIKRLHELQQKSYLTKEEFEELKNNTYIERFELRDECDNSYI
                     YTFYTNDKCNDIKFIKSQFIVTLIKIGFLCECGGVFRQKKIVDEYDYGYNAIYKCDSC
                     GKELDKEVENYD"
     gene            52186..53196
                     /locus_tag="PC466_000532"
     CDS             52186..53196
                     /locus_tag="PC466_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4116 domain-containing protein"
                     /protein_id="HDF2767959.1"
                     /translation="MHEDKNDIFESIDTEDFDNKTEEECLELVRKNGLNLIYIKNQTE
                     EICLEAVRQNCNAIKCVQNQTEKICIEAVKQDWRMLEFVEESTEEICMLAINQDGTAL
                     KYIENQTEELCLRAVEKNGAALEYVKEQTEEICIEAVRNSEFGLARVKNQTEKICMEA
                     VKHCSYNLKWVENQTEEICMEAVRQNGLDLKFVKNQTETICLRAVRQNGMALEFVKEQ
                     TVGICLKAVRQYGMALKFVKEQTEEICTEAIKQDKRALSFVKGDKEKYKALYDNNEPF
                     AKRYVRNVIEKENRALIKKGEENAKIKIAGKLYDRGMSFEDISDIVEIEISKLKVSLG
                     VF"
     gene            53332..53820
                     /locus_tag="PC466_000533"
     CDS             53332..53820
                     /locus_tag="PC466_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HDF2767960.1"
                     /translation="MKITVLYQTRSGNTERVAKLIEDGAKKVDGVDVKLMRLDNIDLD
                     YLNESKAVIFGTPTYLANTTWEVKKWFDEDSKKVNLAGKLGAVFATCDYICGGPDVAI
                     LTIVGHLMVKGMLVYSGGGSLGKPFIHLGHVHSIEGPELQDEKAIIFGERIATKAKEL
                     FA"
     gene            53996..55924
                     /locus_tag="PC466_000534"
     CDS             53996..55924
                     /locus_tag="PC466_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDF2767961.1"
                     /translation="MVWHIEYEIFSAIIVIFLMVYFFRSKFIPTLQNKIYCALLIFSF
                     LFILSNILGSFCLNNIDKIPIFITFLLNQIYLLLLPIPAALVSFYVMAIIYQDIRYMK
                     KRLLFLSIPLIICIILSITNPFTHILFGLSKETGYIRGCGYVATFASFFFYAIYSAFL
                     SFKYRKAMHESKIWAIRGFLIVSIVAIILQAIFLQYLLTGTACACSLLLTYLSMQNRG
                     LIIDDLTGVLNRQSFIQELDLNINTEQSGFIITIALDDFKFMNETFGTKNGDIALKEV
                     GKYLIQIHDVNHVYRIGGDIFSIVVNSQLGIEPDDIIRKIEERFKKPWLVEEISFNLA
                     TSIAVVYYPENAETTEDVIVAIDFSIHEAKRSESRRVVYADASISEKIKKKHVIKNCL
                     KEALKNDGFEVYYQPIFSNSRGRFTSAEALLRLEHKELGFIPPDEFIPIAEQTGLINS
                     IGLVVFEKVCRFIASDEFENLKLDNIAVNLSVVQCMQKNLADDLLYLMNKYNVSPTKF
                     KLEITETVAMGSFNIIKETMERLIDLGVKFALDDFGIAYSGVTNMLSLPFSVIKLDKS
                     LIWSMNEDSRHKLTVETIIALINKLNMKAVAEGVETIKCAEDLIAMECEYLQGYYFSK
                     PVPEDVFKNLLKENTFTS"
     gene            56099..56509
                     /locus_tag="PC466_000535"
     CDS             56099..56509
                     /locus_tag="PC466_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HDF2767962.1"
                     /translation="MNKKKILVPIDGTERSMHSLEFIKGIFKKDEVEVEIMNVKELVF
                     IDGISLAEEIKNSENLGRRILDKAAEIMGEYDVKVHFTFGYPGDEIIRKAKEDNVDFI
                     VMTKSTKKGLTRMIGSVTASVVKQAKCIVMIVPE"
     gene            56531..56833
                     /locus_tag="PC466_000536"
     CDS             56531..56833
                     /locus_tag="PC466_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIBC"
                     /protein_id="HDF2767963.1"
                     /translation="MNKKIVAVCESERSLNSLKTAANDLGFDLVYEIQENDNIKNELS
                     IYDIEDASIVLFVTSDSIESIEKIDRFIDREFYEVDPKYIIEDAKSIVSEILIDLN"
     gene            complement(57049..57741)
                     /locus_tag="PC466_000537"
     CDS             complement(57049..57741)
                     /locus_tag="PC466_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HDF2767964.1"
                     /translation="MKSLNATEKIIDYIKLNILNGTFKINSKLPSERKIADLFNISRI
                     PVRNAINILCKEGILRAVPYSSPIVEGFKKVDLFDDGEIYKNHNIQEFYVESLRARQL
                     IESEATKLAILNATSKELQKIKYTYLKSIEELDKVSHGLIEECYDADLQFHKEIILAS
                     HNPIFIKYYELIPKTVSSNQYFGFKYRNSLKDMISHHNKIMMAFDSKDSYLGYTSMYN
                     HLEDVIQLFQHD"
     gene            complement(57767..58954)
                     /locus_tag="PC466_000538"
     CDS             complement(57767..58954)
                     /locus_tag="PC466_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2767965.1"
                     /translation="MKKISNQKLLLLSIVTFFWFSQYVYIPFQNPYLSACNVSTNMIG
                     IIIGAYGISQCLLRIPVGVFADSINKHKIFILSGIFFAGLASLIRVFSPGGNGFLIAN
                     ILSGISSSTWISYMVHYTNFFSTEHQQKATSTIILVNNLGMLIGFVMSTLFYEKLGMT
                     ALCIMSVLSSVIGTILALNIKNHNSKKIPEKISIKKYLSICKDKRLVFFSFMALIQQG
                     IQMSTTMSFTTQILKNLGSSSTLIGLSSISYMVCAVASSGFASTKFCTKYGPKFWIPL
                     VFILVSAYCFLVPTIKNINIIFVLQVLPGISTGILLSYLTSESMKNVPKHQKSTAMGF
                     FQAIYAIGMSVFPMIVGKISEYTSIQYGYFILAIIAILASILSYTYYKKVDLTLNYDI
                     IQS"
     gene            59290..61167
                     /locus_tag="PC466_000539"
     CDS             59290..61167
                     /locus_tag="PC466_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF2767966.1"
                     /translation="MDYKNIAQEILLNVGGKENVNEVTHCMTRLRFKVKSASKVNKDK
                     LSKTEGVITVVESMGQIQVVIGNKVKTVYDEVIKIVPQSNDVGKKNESQEKQSIINSI
                     LSAVAGIFTPTIPAIAGVGMIKGILSVLAMYYMNKNGVDIKETQSYIILNAMADSIFY
                     FMPIILGYTAAKVFNANKIISMVLGATLCYPTFTALMAGEESVRFLGLAVTKATYTSS
                     VIPIIIAIWALSYVEKVLEKYIPEVIKIIMVPTLSLVVMLPATLFLFGPIGIYIGNVI
                     NFSYKYIYELSPALCGAFVGGLWCVLVIFGAHRALLPIGISDVAQTGRQNLLAFAGAA
                     NFSQAGAALGVFFKTKNQGLKTISMSATITALFGITEPAIYGANLRLKKPMVCAVICG
                     AFGGAIMGMGGAYGNAFANQGVLTIPVYAEAGALGFLSYLGGCAIAFFGSAISTYLVG
                     FEDLEESSNKENSFIKVETKDGVIDITSPVEGECIELSEVKDDVFASKAMGEGIAVLP
                     TKGVITAPTDCEVASLFPTLHAIGLKLDNGAEMLIHVGINTVELNGKYFTKHVNQGDL
                     VKKGDKLISFDIDKIKKAGYDVTTPVIVNNTFDFGQVVSCKSSYVSTNDNIISLVLAG
                     N"
     gene            61479..62885
                     /locus_tag="PC466_000540"
     CDS             61479..62885
                     /locus_tag="PC466_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HDF2767967.1"
                     /translation="MNTGFPKDFLWGASSSAFQVEGAWDKDNKGKTVADYNSFKKSHL
                     QADTKVASDFYHNYEEDIELMKELGMKTYRFSISWARIIPDGEGEINQKGLDFYNKII
                     DKLIECDIEPFVTLYHFDLPFKLVEKYNGWESRETVYAFERFAKICFKHFGDRVKYWQ
                     PHNEQNLIVRVEERINIYDETDSWKIDKMRAQMDYNLCLAHALAVNACHEMIKESKIG
                     AAVSSSVTYPLTSKPEDVYAARMNDNFKVYYMLDMHHYGEYPGYYMKYLEKRNTVPHM
                     EDGDKEILKKAKMDFIAVNYYRTNCAEALPEDSQHPFGLREGTVDFSMYGLFKMSMNP
                     NLEASEYGAAIDPSGLRVALNEYWQRYHLPVIITENGLGAKDILEDGKIHDDYRIDYL
                     RSHINACKLAIEDGVEMIGYCPWSFTDLLSSSQGFNKRYGLVYINRTDHEVLDLKRIK
                     KDSFYWYKEVIENNGIVK"
     gene            62913..63761
                     /locus_tag="PC466_000541"
     CDS             62913..63761
                     /locus_tag="PC466_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDF2767968.1"
                     /translation="MYITKVLNNSLLLAKDDNDEEIILMGKGIGHNYKAGSELNKKDI
                     EKIFVLHDENIKKSIIQLATEIDAEYFGIAQMIIAYGIEKYNLKLMNHIYLALTDHIA
                     FAVRRFKEGIMIENHYLFEIKEFNPKEYDIGKYAITVFKEVLGLDLPEEEIGNIAGHF
                     INAQQDNPYSDRNKRSAKIVNAILQIVHYHFSIVYNKESFYYRRFVMHLKAFSQRFLA
                     NEPSREKIDFIYEQVQKNCKEEYECVKKVGAYMYKEYSRELPRQEELYLMIHIHKILG
                     ELCENS"
     gene            64422..65114
                     /locus_tag="PC466_000542"
     CDS             64422..65114
                     /locus_tag="PC466_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003020373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2767969.1"
                     /translation="MNKVLIIDDDKDLCILLKKSISIEQIEANYCHSGRDGLVELSKQ
                     DYQLVVLDVMMPGMDGFETMEQIRKYSSIPILMLTSKSDNYSKVHGLRAGADDYLTKP
                     FEITEFTARVLSLIRRYTRFNPKNEEPQQLSFKGLLIDLDQHTVTTNGEPMLLPPKEF
                     GVLLYCARHQGKILTKQQIYEAVWGEPYVYDDSNIMAIISRLRKKIELDPSSPIYLQT
                     IKGIGYQFNTEV"
     gene            65111..66046
                     /locus_tag="PC466_000543"
     CDS             65111..66046
                     /locus_tag="PC466_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2767970.1"
                     /translation="MKMDEQTIILFLFLLSIGLLFLSIFAFSKLGHIHKRLKDIEEIL
                     ADVQIGNENRKILIKPCDVMAPLVYQLNEIVYDYENKLLSLKKSDKASKQLMTSLSHD
                     VRTPLTTLIGYLDAVHSGIVIGQEREEYLEIARRRAYDLKDYIDVLFDWFRLNSDEFT
                     LSIESVEIAELSRNILKDWIPIFHEKKLNFEIDIPENRLMVNLDPDGYSRVVNNLVQN
                     VLAHSKARQIKITMSEDSRMVLLRVDDDGVGIARENLPHIFERLYKCDKGRSEKGSGL
                     GLSIVSQMVERMGGQISVESEIGKYTVFTVSLPLI"
     gene            66194..67117
                     /locus_tag="PC466_000544"
     CDS             66194..67117
                     /locus_tag="PC466_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013273760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2767971.1"
                     /translation="MNNLIIETKNLTKQYGAQKSVSNLNIHVQKGRIYGLLGRNGAGK
                     TTTMKMLLGLTKPTTGEIKIFGQDIHNNEKKLLPRIGCLIESPGFYPNLTGTENLKIF
                     ARLRGIPKKNAVESALDVVGLPNNDKKLFSQYSLGMKQRLAIALAIMHDPQLLILDEP
                     INGLDPIGIAEVRKFIRDLCTERGKTILISSHILSEIALLADDIGIIDHGILLEEESL
                     AQLEEKNSKYIHFAVSDAAHAARLLETQLNLKNFKVADNYNIMLYDTDVSVAEINRAF
                     ILNNIEVSESHLCEDTLEDYFKKVTGGEGIA"
     gene            67101..67871
                     /locus_tag="PC466_000545"
     CDS             67101..67871
                     /locus_tag="PC466_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2767972.1"
                     /translation="MKELLDIISCEFSKLKRLKFILISILGACLFPIPATILIAKDNL
                     PFEQLFKLVVNFGYFLLLPIVLSIVASQLFFIERDNDVLKNLATVPVPKGKLALAKLA
                     VLLFISLFYSVAGLGATIIGGFIVGIVEGVTVKLGMSIAFGIMFFVTVLPVVVLIVYF
                     NRSYIFSIILSFVYAIFNFSISLNIINFEPNNPLLSVLPAPVIMRWWMAFWGDPTGEY
                     TALRQPYLLSTPACVGILCLITIIAVLLICMIYKKQEN"
     gene            67881..68663
                     /locus_tag="PC466_000546"
     CDS             67881..68663
                     /locus_tag="PC466_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2767973.1"
                     /translation="MLDIITTEFQKIKRYNILWIGVVAVLFSALLAVFQVVSSHGSDP
                     LTYESFANGVIWNNFSLSFPFGITLIGGYLINREYTDQTLKNILTVPISLRKLLVGKL
                     IAVGGIAVLLSLFSFLCTFILGLLFCNINISVTLIVKSLVQILSVNLYCYVAVLPIIA
                     YFGRKQNAFLTGVGIAFVYGFCGVFVAGRNLTDFYPITAGLGLVGYNNGAGTVYQPLI
                     GAMTLIVILILTTILLVFTPNYDKVMTISKKKGIKHKKYSHK"
     gene            69040..69576
                     /locus_tag="PC466_000547"
     CDS             69040..69576
                     /locus_tag="PC466_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rubrerythrin family protein"
                     /protein_id="HDF2767974.1"
                     /translation="MNLKGTKTEKNLMAGFAGESEARNKYTYYASKARKEGYNQIAAI
                     FEETANNEKEHAKLWFKLLHDGMPSTEENLKDAAAGENYEWTDMYAKFAKEAREEGFD
                     KIAYLFEAVGKIEKEHEERYLKLLENLNEGKIFKRDEEVVWQCQNCGHVYVGTEAPEK
                     CPVCDHPKAYFNIKAENY"
     gene            69608..69997
                     /locus_tag="PC466_000548"
     CDS             69608..69997
                     /locus_tag="PC466_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HDF2767975.1"
                     /translation="MKFSKQRELILNEILNNPVHPTADYLYENLKKDNPNLSLGTVYR
                     NLAQLTEHGFIRKVSIPGYPDRFDGRIDNHYHIICEVCGEVYDLESEVLNNLQELISE
                     ETDIKITSYNISFKGICNNCKRCSQVG"
     gene            70034..70420
                     /locus_tag="PC466_000549"
     CDS             70034..70420
                     /locus_tag="PC466_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="desulfoferrodoxin"
                     /protein_id="HDF2767976.1"
                     /translation="MCSEQKFFICETCGNLVGMIQSGGVPIFCCGKPMKELVPNTTDA
                     AVEKHVPVIEVDGNNVTVKVSSTTHPMTKEHHIAWVYLMTEQGSQRKCLAVDGEPVVK
                     FALNDDDKVISAYAYCNLHGLWKAEL"
     gene            70547..71989
                     /locus_tag="PC466_000550"
     CDS             70547..71989
                     /locus_tag="PC466_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HDF2767977.1"
                     /translation="MSIYKCSVCGYIYDESKNDKTWDELSEDWECPVCTKGRSYFGKI
                     STVYYEEDEKIAEDIVENESKLNTEKEGDLNYLSTYLRRDDEVEKHMDIIHEMAVTGK
                     SIIEPMRTKLPVISWDDILIMGAQLNPLPLNEHDEVNTTTIIGKKAKKPMIIENPVYI
                     SHMSFGALSKELKIALAKGAAQNKTAMCSGEGGILPEEKEASYKYIFEYVPNKYSVTE
                     ENLKNSDAIEIKIGQGTKPGMGGHLPGEKVTEEIAKVRNKPVGQDVISPSCFEEIQSK
                     EDLKKLIDELREVSEGRPIGVKISAGHIEKDMEFIAYAKPDFVTIDGRGGATGASPKL
                     LKDATSIPTIFALYRARKYIDTHGLDIDLVITGGLRISTDFAKAIAMGADAVAIASSA
                     LMAAACQQYRICGSGKCPVGVATQDEELRKRLHIENSANRVANFLNVSLEELKTFARI
                     SGHKDIHDLSVDDLYTVNSEISNYTNIQHV"
     gene            72286..73101
                     /locus_tag="PC466_000551"
     CDS             72286..73101
                     /locus_tag="PC466_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF2767978.1"
                     /translation="MERLKIQVLVDNNTYIDRYFVGEPAVSYYIEIDGNRILFDSGYS
                     DVFISNAEKLNIDLGNLTHVVFSHGHNDHTRGIQFLENRYDLSTVELISHPNCFIPRK
                     HGEKSIGAPFSAEEIKNIFMYNPKDKPFNLSKNCVFLGEIPSINNFEKRAKIGKCKIG
                     DLWEDDYVLDDSAIVCKTDKGIFIVTGCSHSGICNIVEYAKRVCGDDRVIGILGGFHL
                     FELNNRLDSTIQYLDKEEIRMLYPCHCVSFKVKAKMNEILNINEVGVGLTISI"
BASE COUNT        26818 a         9517 c        13322 g        23535 t
ORIGIN      
        1 taataacaat tcaaaataaa taacttatgt aagaaccgta ggaactacgg ggatagcctg
       61 tggagaatta gtaagacata ttttagtatg caaaattctg tgaagcagga acactgtgac
      121 tttagtcatg ggaggttcag aaaatatagc tatgttttat atactgtagt tttgaacata
      181 gaaagtttaa taaattatag tatatattaa tttttaataa ggtaagaaag tagaaagaag
      241 gatattttat ggatataata aaaaaattaa gtcatggatg tacattagat tgtcatgatt
      301 gttgtaaatt caatgtttat actaaagaaa ataatgtagt aaaaattgaa ggagataaaa
      361 atcatcctta tacaaaaggt tttatatgca aaaaagggat ggctcattta gatagattaa
      421 atcataaaga tagaataaag actcctatgc ttaaagttga tggagtatgg aaagagattt
      481 cttttgataa ggctatagaa ataatggcag aaaagcttac atactataaa gaaaagtata
      541 catcaaagtc tgtcatgcat tatgaccaat atggaagtgg gtctgtgcta aaatacatag
      601 gagatatatt ttttaatttt tatggaggtg ttagcagaca taagggtggt ccctgttgga
      661 gtgcagggat gcatgctcaa aaatatgatt ttggagtagc taagagtcat gctatagaag
      721 atatgttaaa tagtaaaagt atatttgtgt ggggaaaaaa tccagcatat actacaattc
      781 atactatgca aataattaaa aaagctaaag aaaaagggat aaagatagta gtgattgacc
      841 ccatatatac aaaaacagct caaatagcag ataagtatgt acaggtaaat cctggaacag
      901 atggagcttt agctatagct atggcaaaaa ttatagtaga agataaatta tatgatgaag
      961 aatatataaa ctcgtatgtt attggttttg aagaatataa aaaatattta tcttcattgg
     1021 aattaagttt tttaattgat gaatgtggtg ttaaagagaa tgatataaga gagttagtgg
     1081 atttatatac taacaaatat tcaagtataa atgttggata tgggcttcaa aaatataaaa
     1141 atggtggaaa cacaataaga gcgatagatg ctttaggtgc tataactggt caaataggat
     1201 ttagtggtgg aggggtaaac tatgctaata aagtttatcc aagtgttata aattctgacc
     1261 cttacaatag ccaatcatat ggtgaagata gggagtttta tgtaagtaat atcagtaaat
     1321 ttatagaaga atctttaaaa aatacatcaa ataaagtaaa ttatgcatca gatgaacttg
     1381 atacaacatc aaataaagta aattacatat cagatgaact tgatacaaca tcaaataaag
     1441 taaattatgt atcagatgaa cttgatacaa catcaaataa agtaaactat gtatcagatg
     1501 aacttggtat ggcattacat aaagtaaatt gtgtatcaga tgaacttgat atgacatcaa
     1561 ataaagtaaa ttatgtatta gatgaacttg atataacatc aaataaaaca gattatatat
     1621 caaatgaatt gtataattta tctaataagt caatcaaaga taatattcct ataaagatgg
     1681 ctgtgataac taaaagtaat atgctgaatc aactgccaga tttagtagaa ttggagaggg
     1741 tgttttcaaa aattaaattt aaagtatgtt ttgatatgtt tatgactgat acagctactt
     1801 tatgtgacat gtttataccg tgtacaaata cactagagag tgaagatata atttatagct
     1861 caatgaccaa tccatatata acctataatg aaagagctgt aaagccagca cataaattga
     1921 tggatgaata ttatttcttt atggagctag ctaaaaaaat gggattaaat gattatcctt
     1981 ttgtagaaaa gagaacttat ttagaaaaag tgattgaacc acttaagcgt tttgacaaaa
     2041 atctggatat agaaaaactt aaaaacaatt actttactat acataacctt gttgcttggg
     2101 aagataagaa gtttgagact ccatctggaa aatacgagct ttattcagaa agtataaaaa
     2161 acttgggaat aagtccaaca cctgtatata taagcaataa atataaagaa atagaagata
     2221 aaaatatttc ttttagatta ttaactaatc atcatgcaga tactttattt agtcagcatt
     2281 ttatggacaa aaaatctata gctcaagcat atataaatca gagaatggct aaaaaagtag
     2341 gtattgagga caaagatatt gtgatattga ggtcaaaaaa ggcaaaaata aatgtacaaa
     2401 taaatataga tgatggagta ggtaattata tagtaaaaat gtatgttggt tggtggaaga
     2461 aacatggaaa tcctaatagt ttaacagaca ctggtatatc agattttgga ggtcaggtaa
     2521 catataatga aagtatggta gaaataatac gacaaaacta gttaaatttc attgaaggaa
     2581 taaaaatata attatagaat tgattaaaag ttactatttt tacaaaacta ttgaaggagg
     2641 gatttttgat ggtaaattat tccttagaac ataagaatct atacatagaa tttatgtgct
     2701 cagaactaga ccaccatgta gccaatgaaa taagggaaga aatagataac ttattaagtg
     2761 taaatcaagt aaaaaatgtt gtatttaatt ttgaaaatat taattttatg gattcttcag
     2821 gtataggcgt catcataggt agatataaaa agatttctaa tgaaggggga cgagtttcag
     2881 taattaatat aagttcacga gttaagaaga tttttgattt atctgggtta aataaaatta
     2941 ttggcattta tgatacgtat gaagaagctc taagttcttt gtagggagga gtatgtgatg
     3001 aataatatta tggaagttaa attttcggca atatctgaaa atgaaagttt agcaagagtt
     3061 atagtagcat cctttgcagc taagttagac ccaacagtag atgagttagt agatataaaa
     3121 actgctgtct ctgaggctgt tacgaatgct ataatacatg gatatgaaga agacagttct
     3181 aagtttgttt tcttaagatg tgagatagaa ggaaatacta taaagattat agttgaagat
     3241 gaagggtatg gaatagaaaa tgtggagaag gcaatggaac cactttatac atcaaaacca
     3301 gaacttgata gatcaggaat gggattcaca gtaatgaaaa gctttatgga cgatgtagag
     3361 gtaagttctg taaaagataa tgggactaga attgaaatga ctaaaaaaat aaatgtgcct
     3421 aaataaagtc caaaagtgag gttttattat ggaagtaact gttgccagag aagaaaaaaa
     3481 acctcttctt agtcatgaag agactctaga acttattgaa aaagttcaaa atggagatga
     3541 agaggcaaaa gaaatattaa tatcaagcaa tttaggtcta gttaggagcg ttgtatctag
     3601 atttttaaat ataggatatg atagagaaga tttatttcag ttaggttcta taggcttaat
     3661 aaaatcaata tataaatttg acccaaaatt taatgtaaaa ttctctactt atgcagtacc
     3721 aatgatttta ggtgaaataa agagatactt aagagatgat ggtatgataa aagtatcaag
     3781 gtcgttaaag caaatagctg taaaggcaaa gatggaaagt gaagctttaa ctaaaaaatt
     3841 aggtagagag ccaagtatag aagaattagc taaagcaata gatgtagaaa aagaagattt
     3901 agtaatggct atggaagcta atttcaatgt tgagtatttg caaggagtta ttcatgaaga
     3961 ggaaggttct ccaatatgcc ttattgataa aataagcatg aaaggagaaa gtgaagaaga
     4021 aaaagtagtg gataacatat tgttaaaaga catacttgga agactggata agagagagcg
     4081 tcaaataata gttctcagat actttgaaga catgactcaa agtgaaatag gagagatgct
     4141 caatatatca caagttcaag tatctaggat agagaagaaa gtattgtcta agttaaaaga
     4201 atatatatcg tgataatact tatgatatgt agaataacaa aatataataa atatattact
     4261 aaaataaaat gtaataactt tttatgttaa gtttttaaat tattaaaaga tactaaaata
     4321 ataaaaagca ttaaaaaagt aaaaatataa aaacaaggtg tctttatgga aaaatagatt
     4381 ttttctttat taggcatctt ttttattttt tgaccaaact ttagatagtc aaaataaata
     4441 ataggtttat ttttttaaaa ttaacaaata atactttaga gaggtgttta gtatggataa
     4501 aaattataaa aaatatgtag accaaataag cccaaaacct acatatttaa aaaactatac
     4561 acttgcattt attgtaggtg gaattatttg tatgataggg caagcaataa atgatttgta
     4621 tatgaaagtt ggaggtcttg ataaactagg tgctagttct gcaacatcaa taacattaat
     4681 atttataggg gcatttttaa ctggattagg agtttacgac ctaataggaa aaagagctgg
     4741 agctggttct ataattccaa taacaggttt tgctaactca atagtatctc cagcaatgga
     4801 gtataaaaga gaaggctatg tattaggtgt aggtgcaaac ttatttaaaa ttgcaggacc
     4861 agttttagtt tatggtatag gttcttctat tttatgtgga attatttatt atatttttaa
     4921 gatgttttag atgattttta tttaatttaa attttattaa ttatgaagaa ggtataaaat
     4981 ctgaaaatag ctactaaagt aactaattga aaaataattg tgcagattta attaatatta
     5041 aaaatttgaa tagtaaaatg caaaattaaa aaggtgtgaa aatatgaaaa ataaaagaat
     5101 tggaaaaaga acagtcaagt tagaaaataa accaaccata atatcaactg gaactatagt
     5161 gggtcctaag gaaggtgaag gaccactaaa ggactatttt gatatgatta tgactgacga
     5221 tttatatggt gaaaagactt gggaattagc tgaaagtaaa atggtagaga ctgcatccca
     5281 acaagctatc caaaaggcag gtaaaaaatt gtcagatgta aattatatgc taggtggcga
     5341 tttaataaat caaatagtgc cagcatcatt tgcagcaaga gaactggcta ttccattttt
     5401 aggtatatat ggagcttgtt ctacaatggc agaaggtctt tgtataggtt ctatgcttat
     5461 agatggtggt tttgctgatt tagtactgtc aggtacatca agtcactatt gtacagcaga
     5521 aagacaattt agattcccac ttgaacttgg aaatcaaaaa ccaatgacag ctcagtggac
     5581 agttacagga gcaggaagtg tattattagc tcctaatgga gacggtccaa aagtaaagta
     5641 tgttactgtt ggtaaagtaa tagatgaggg tattgatgat ggtaataata tgggaccagc
     5701 tatggctcca gcagcaatag atactatcta ctcttacttt gaagatacta atgatgaccc
     5761 aaatagcttt gatataattg ctactggaga tttaggtact cttggaaaac agatagcaga
     5821 agactttcta aaagaaaaag gtgtagatat atcaaaagtt tatactgact gtggtataga
     5881 gatgtttaac cttaaagaac aagatgtcca ctgtggtgga agtggatgtg ggtgttcagc
     5941 tacagtgttt gcaggatata tatatgataa gttgagaaaa aaagaattta acaaagtaat
     6001 gcttgtatca acaggagcac tactttcacc gacaagtaca ctacaaaagc agacaatacc
     6061 atgtgttgca catgcagtag taatagtaaa tgagtaggaa gtgatataat atgttaatgg
     6121 actatgtaag agtatttatt gtaggtggaa ttatatgttt aatagcccaa gtaatgatgg
     6181 attatttcaa aatgcaaact ccatatgtta tggtaacgta tgtaacaact ggtgtagttt
     6241 taacttttct aggactttat gagccattag ttaagtttgc agcagcaggt gcaacagttc
     6301 ctataatagg atttggatat tcacttgcta caggagtaat aaaatcaatt caaagtgatg
     6361 gttttttagg tattttttta ggaggtacaa ctgctacagc tggtggaata gcagcagcta
     6421 tattctttgg atatattatg tcagtagtat ttactccaaa agcaaaacca taaatcttta
     6481 ttaaaagaat aataagtttt tgaaataata actttttata aagcaggtgg atatctttta
     6541 gattccacct attttttata taaagaagcg tttacataat tgaagttgac aattatttac
     6601 aacatagtgt agtattatat tatcaaaata aaatgaagtg aagtagggga taaagatggt
     6661 aactattaaa gatattgcaa ggaatctagg tatcagttat tcaactgttt ctaggtgctt
     6721 aaacaataat cctaatgtat ctgaaaaaac aaaaaagaaa gtagtagaag aggcaaatag
     6781 actagggttc cattttaatg taaatgcaag aaatttagca aaaaaagaaa ctaacaggat
     6841 aggggtaatc ttttcaaata attttaatca tcaagatact agaaagtttt ttagtgatat
     6901 aatggatagt tctataaatt ctattgagac taataaatac gattttataa tacagcctaa
     6961 taataacatt agtggtgata gtaatgtata taaaatggta aatggacaaa tggttgatgg
     7021 attagtaatt gtgtctcaat caataaaaaa agaagagtat gattttttaa aagacaataa
     7081 ttttccacat gtatttatat attttaaacc atcttttgta ggagaagtag acaatttctt
     7141 ttgggacgat aacgtgtatg gaggttatat agctaccaag catttaattg accatggtca
     7201 taaagacata ataacagtaa cttcagatga taggagttca aaaatgcatg aagatagaac
     7261 taagggatat ttaaatgcta tggaagaggc aaatttaaag accgaagtca ttaaatctaa
     7321 aatggatttt gaatctcaag ttgaattttt agaaaaatat attgataaaa taaaaaaagc
     7381 ttcagctata tttgtacaac aagatgtacc tgcgatttct ataatacaag agttaaaaac
     7441 tacttatggt ataaatgtac cagaagatat ttccataata gggtataata atattgaatt
     7501 aatatcatat tttaggtcgc atttatcaac aatagatgac ccaagagagc aagttataaa
     7561 aaatggagta gatagtttag taaatataat aaataaaaag agtacagaac acattccaag
     7621 aaaattatat ccaaggttaa taatacgaaa tagcgttaaa agaataaagt agtaagcttt
     7681 taagtatcaa aagtttatta aaaatattat agattatgtg aagtttttta acaaacaata
     7741 taaataaaaa ttaaaaggag taggtgtata taagtacatt gtactccttt atttattgag
     7801 atagttttta taatatgaat gaataatttt attcaattat ttgaaaatcc gttattttaa
     7861 caatataaat taataaatta tttgtatttt atatcatgaa tctataatat ttttttgatt
     7921 cataactaaa agtatataaa aatgatgaat aaatatatat tatacattat caatgatagg
     7981 ttatataata aaatcactaa caattatatt ataagaaaat tataaaaatt acaaggaggt
     8041 atagaaatga aagaaaaagc agggattaga aatgccataa tagcagcctt tataatcaca
     8101 atattggcag aattaattgg acctatttca tttaaagtta tgggaataaa tgtaacttta
     8161 cttagtatac tatgggctat attcatagga atggctgttt ctcctcattt attagggaga
     8221 gttataccag ccttaaaaaa gtttataggg gataatgaaa taaatgtatc tccatattta
     8281 ttatctttga cactatatcc attaggaata atgtttggaa ttaatgcagg gcctaaagtt
     8341 ggtatattac ttcaagcagg accagcactt ttattacaag aatttggtca tatgggtaca
     8401 atgttgatag cattacctgt tggagtagca ttaggtcttg gaagaagtgc attaggtggt
     8461 actttttcat tatgtcgtga cacagcacta ggcattattg gagataagta tggattaaac
     8521 tcaccagaag gtataggaac actaggaact tacataagtg gtagtatatt tggaacatta
     8581 ttattttcat ttttagcacc agtgggtgta cttttaggat ttcatccata tgctttagca
     8641 atggcatcag gaatgggtag tggttcaatg atgggagctg caacagcatc attaatgaat
     8701 acggttccac aaatgtcaga gcagatttta gcatattcag ctactagtgg attgattaca
     8761 gctgttactg gaatatatat agaattattc ttatctttac cagtagccaa ctactattat
     8821 agcaaagtag ctccagttat tgaaagattt agaggaagaa aaacaagaag aacaagtaat
     8881 aaattgtaaa ggaggatata tatatggaaa aaacttttaa gactattatg gagcagataa
     8941 aaatagtatt gtttatatat attattactt gctttggaca aatgatagca cttaagactc
     9001 aggctcaaga tttgttgatt ggaagtatat ctggattttt gttggtgata attgctatta
     9061 taataaagaa ttttgttaaa aaacctaatt taccaggttt tgcatgggct acattagttg
     9121 cattcgtttt atcgcttcca atatctccag tgggggatat catagcaaca aatgtaggga
     9181 aaatcaattt tatgtctaca gtaacaccat tattagcttt tgcaggaatc tctgtaggta
     9241 accaattaga tatattaaag actttgagtt ggaagttagt agttatatca tttatagtta
     9301 tgacatctac ttactttggt tctgctttta tatctcaaac agttttaaga ttaaatggaa
     9361 tgctttaagg aggtagtaaa tatgaatgaa ttaaaagcaa aaattaaaga ggaaataaag
     9421 ttattatctg aagagaaaaa gacatcattt gaaaaagttt ctgactattt attttcaaat
     9481 ccagaattag catttgagga gtataagtca caaaaagcat tatgtgattt gttagaagaa
     9541 aatgaattta atgtaactaa aggtgtagga ggattagaaa catcttttga agctgtgtat
     9601 tcaaatggaa ctaatgggaa aacagttgct tttctagctg aatatgatgc acttccagga
     9661 atgggacatg catgtgggca caatatcata gggacaagtt ctgttggtgc aggtatcata
     9721 ttaaaagaaa tcatgaaaaa acataatata gaagggactg taaaggtttt tggaacacct
     9781 gcagaagaaa gagtaggtgg aaaaataact atgattaaag aaggtgtatt taataatgta
     9841 gatgctgcat taatcttaca tccaagtgat gcttcaatgc ctgatgatat atcatttgct
     9901 caagttaatt taaaatttga ttttactggt aaggcatcac atgctgctgc ttttccttgg
     9961 gaagggaaaa gtgccttaag tggagtaata gcactattta acagtgtaaa tagcatgaga
    10021 ttacatctta aagattatgc aagagtacat ggaattataa ctgatggagg tagcatacat
    10081 aatataattc ctgaaaaatc tacagctata tttaatgtaa gagccttaag catagaatat
    10141 ttaaatgaga tttgtgaaat gcttaaaaat tgtgctaaag gagctgcaat ttctactgga
    10201 actaatgtag aaatagttca attagatgaa atatacaaag agattaagaa tgattctgaa
    10261 ttagtgaata tagttagaca aaattttgaa gttttgggtg aagactatgt tgaaagagat
    10321 ttaagtcaag gtataggttc aactgataca ggaaatttaa ctcatgagat acctgcaata
    10381 caagcatata taaaattaaa agaaaatact gcaactcata cagatgaatt tgctgttgca
    10441 gctggtggtg aagaaggcaa agtagcactt ataaaagcaa ttaaggtgct agcaatgtgt
    10501 ggagtagata ttttgtatag taaataatat ataattttaa aatatattaa gaaaggaaat
    10561 cggattagac atgatattaa aacaagtaat agaggtttat gacattttag ataaagcaaa
    10621 tgctaatggg gaagaagtaa aaacttactt acaaggttat ggtgaagtag atgtaactgt
    10681 aaaagaattg tcttcaagta aaggttcaac agatttagta aagcttacaa ttcctgggaa
    10741 aaatggaaaa ttaaaaggtg gagatgctcc tactcttggt attttaggta gattaggagg
    10801 gattggagca agaccagaag ttataggttt tgtctcagat ggtgatggag cattggtagc
    10861 aattgcagtg gctgctaaac ttttggatat gcaacgaaaa ggggacatat tagatggtga
    10921 tgttgtaatt tcaactcata tttgcccaga tgctccaact aaagaacact atcctactcc
    10981 ttttatggat tctccaattg atatgatgac tatgaatgaa aatgaagttg atagtagttg
    11041 tgatgcaata ctttctatag atactactaa aggaaataga gtaatcaata ctagaggatt
    11101 tgcaatatcg ccaactgtta aagaaggcta catattaaaa actagtgata accttttaga
    11161 tattatgcag actgtaacag ggaaatctcc atttgtattc cctttgtcta ttcaagatat
    11221 aacaccatat ggaaacaatc tgtatcactt aaatagtatt ttacaaccag cagtagctac
    11281 agatgcacca atagtaggag tagcaattac aacagagatg cctgttgctg gatgtgctac
    11341 aggtgcaact aattttagtg atttagattc agctgggaga tttgcaattg aagttgccaa
    11401 gctatttggt agaaataagt gtgatttcta tgataaagaa gagtgggaaa tgcttattaa
    11461 gagatatggc aaattaaata gatttcaaac atttggtata cagtaattag aaaaatatta
    11521 agtttatata atttgtgata caactattta agaagatata aacaattagg aataaaagta
    11581 agaataaagc acttagttaa aaactttaaa aaaaaatatt tatttgttta tataaaaagg
    11641 aggattctgg ttattgggat tctctttttt atgaatacaa ataatatatt gtaattataa
    11701 aaaaaggagc gtttcaaagt gattttttta atcaccttga gacaactcct tatatttttt
    11761 atttaaattc tattttttat tgactgtata gctattttca ccatcataag gtggcatgac
    11821 cttgaacagc gtggttttgt aaagttgggc accacaaaac aaaaaatcaa caagcccttg
    11881 tgtggtctgc tgacgtgttt actatactat actttcccaa aaaccgcaag cactatggga
    11941 ggctataagg cggcgaccat tcaggggcga tcccctcgaa accgggatag ggttcccatg
    12001 tgggacataa taaagagcgc cccggaggta tcaactacca tccggggcgc tctttattat
    12061 gtcccgtggg aaccatgccc acgaagcagg gcgtacaacg gacagatagg tcctaccctc
    12121 ctgacagact ggaatctcaa tcccatcgaa aacaatcata acaatcatgg caagattata
    12181 tacactcctg taaaatattt ttgtgtgtac catgaagtac tgcttgccac tattgagaac
    12241 ggataaaagg gaagtacgta ttataccaat aaggtgaacg aaacaaaata ctcatttgat
    12301 aaagttaaat aaacctgtcg gaaccccacc aatccggcaa gagctcactc aatttaacag
    12361 ttttttctgt ttcgacatta actaaaatct caatacaagc actatcctta tcaagttgca
    12421 ttaaatattc acgacaagca ccacatggtg agccaacact cccattgctc atcacacaaa
    12481 ctaatttagt aattttactt tcgccatttg ttatcatatt ggcgatagca tttctttctg
    12541 cacacattcc caatgtacag gctgtatcaa tacacacgcc agtataaaca tttccgctgt
    12601 cggtaaggat tgctgcggca accccaccag catcgataaa aggtgaaatt gtgcgtggat
    12661 ttaattttcc cctagcatta ttataaagtt ccttccattt catcaggttg atcctcctgt
    12721 tgtatccata taaataatct tttatacgcc ttttccgcct aaggcacaca acacattact
    12781 cgcttttttc attctaatat tcgtgcgtga aaatgtcaaa cggtttactt cgtttcatta
    12841 cttcatactg ctgttcataa ccctgtttgt tcacttgggc accattcgag caccaattta
    12901 cccgtttcag ggttgtagcg aacacagcag aaatgctcat ttcatgggct tttctggcta
    12961 gaaaaaaaat tttatcgctg ccagatattt actatttttt attaagttgc tggagttcca
    13021 ccaccatcag gaggagtagt agagccacca ccattatttc caccattatc aggaggagta
    13081 gtagagccac caccattgtt tccgccatta tcaggaggag tagtagagcc accaccattg
    13141 tttccgccat tatcaggagg agtagaaccg ccaccattat cacctgtgtt attattgtta
    13201 ttattatttt cttctggttg gttattgtct ggtttttttg tatcttcaga tgatggttga
    13261 gaacttactt tagtaggagc agtaccttca ataaatgctg ctttagagcc agaagattgc
    13321 tttcctccat cctctaaatt aatttttgta aaatatacat ttttaggaac ttcaaattca
    13381 gtaaccgtta aattagcatg tattttttcc ataatttttt cccatagttt tgcagtacta
    13441 gtacttccat gtggtacttc tctacgtttt atagtgttac cagaatcatc ttttctacca
    13501 gcatcatctc caatataagt tgcaccaaca taataaggag tgtaaccgac aaaccaagca
    13561 tcatatgcac tatttgtagt acctgtttta cctgctacag gcattccctt tggaagtgta
    13621 gcaacaccac cagtaccttc agtaattacg ctttctaaca tatctgtaac aacataagct
    13681 acttcagggt ctacaacttt atgttcttca ggagcatttt taactaataa ttgaccatca
    13741 aaggtagtta tagtagtaaa aatagaaggt tctacataaa caccttgatt tgccaatgta
    13801 ccataagcag cagccatttg aagtggagta ataccattcg ccataccacc tagtgtcaat
    13861 gatgggaatt ttctatcact tgcttcagat gaacctgagt gattattctt taaagttgtt
    13921 ataccaaagt tctttaagta atccatcatt atatctacac attcatcata agagtctcca
    13981 agcatttcag cagttttgac agctatcgtg tttgaagatt tagcaagtgc tttacgtaaa
    14041 ctcatagaac catgaccagc agtagtagtt cttggattcc atttattatt ttcttcaaac
    14101 ttatatcctc ctcgagaatc acttagagca gttgattgtg ttatttttag ggtatcaata
    14161 gcaggtgtat atattgctaa aggttttata gaagaacctg gctgatgagg gttagtagca
    14221 cgattcaaag tttttctacc acttatattt cttcctccag ctagtgctct tatttcacca
    14281 tttttataat ctaagattac cattgcagct tgtggttggc taactccatc agggccgacc
    14341 atatgtcctg ggaaattgct atttctatca aattcttctt ctaaagcatc ttgcatttta
    14401 gggtctatag ttgtgtttac aattagacca ccattgtaga ataagttttg agcttcatca
    14461 tttgtatgtc cttgttccat taaagcattt ataacttcac tttcgataag gtcttctaca
    14521 gatgaagaaa ctttatctga tgattgaggc aattttattt ctattttagc tttgattgct
    14581 tcatcatatt cactttgttt tatatatttc aattctaaca ttttctttaa aacaatttct
    14641 tgtctttttt tagcttcagg gttacttaca gcctttctaa caactaatgt acctgctttt
    14701 aattgtctat aagtatcatt agatataagc tcccaagatt ttattttttc aatcatatca
    14761 aagtccactt gagtagggtc atctaaatca tcatcagttg tgttaacaaa aaataataat
    14821 ttattttcta aatcctcctt agtttcattt ccctctaact tagaagtttt ataggctgaa
    14881 aatcttgatg gatttttagt tgaaccagca agaagtgctg actctgctag agtgaggtca
    14941 gctgcagact tatcaaaata accacgtgca ccagcctcag cacctgctag acctctacca
    15001 acgaagaagt tatttaaata agtttctagt attttatctt tacttactgt tttactcatc
    15061 tcatgtgcat agtaaatatc ctttatttta cgaggtatag tttgctgttc agttgttaac
    15121 agcattttgg atacctgcat aggaatagta ctaccacctt gcttagtacc tgtaagggtc
    15181 tttaatactg acctaaataa acctttaata tcgacaccct tatgctcata aaaacgctca
    15241 tcttctattg caattacagc atgttgaaga taaggggaaa tcttatctaa tggaacgggt
    15301 gtctttttat ttacacttgg agctgtagac aatgtttttc cattagcgta tttaatagta
    15361 gttgtttggt tcgtctgttt atctaaaaca gcttctgtaa ctggagttac atctcttagt
    15421 gacgcaaata ctagaccagc agtacctgct gtaccaacaa ctagtaaaac taaaaatact
    15481 atcccaaata ctcttagttt tttaaattta tcgctttttt tagatttttt cttgtttttt
    15541 gttgaacgag tcttgttagc tgaagttcta ttaattggtt tatttgtatt accagatgag
    15601 ctaacttttt ttctcctgat tttatttcca tttttatcat tatcgttatt cataagattt
    15661 taacctcctt acttaatgca atattataac acaaatagga gtagttttgt aattaataga
    15721 aaaaatgaat ttgctataat attctgtaca ttgtatatgt ataaacgtaa tatattaaaa
    15781 agtctatatt tttattttat ttatttttga caaatattat aaaaattatg ccaaagctac
    15841 atataaataa ataggagggg ataattttga atagaatagt agatagaaaa acaaaaaatg
    15901 aatttagaaa aatcatagct atttttttag taattctttt cttgtctgta tttataggca
    15961 gttttatata tatagataaa actttaagac cgacaataac agttttagca gagactaaag
    16021 ctcttgaact agcaaatagg tcgataaata aagctgttgc tgagatggta gaaggaaaaa
    16081 taaattatga agatttaatg gatatacaac ttgataataa tggtaaaata actatgatac
    16141 aagcaaacac tataatgatg aatgaaattg catctgcaat agctttagaa atacaagatg
    16201 aattaaaaaa ggataagaca gcaagttctt acatacctat aggaacagca ttaggaagtc
    16261 ctatattagc taaatacggt cctaaacttg aagtgtctat tgaacctata ggaacagtat
    16321 cagtaaactt taaaacggaa tttgagtctt caggtataaa tcaaactaga catagaatat
    16381 atttagaagc tcaaacacaa gttaaagtag taataccact tataacttca acaaaacaaa
    16441 ttaaagctca aatacctatt tgtgaaacta taatagtagg tgatgttcca gaaagttatg
    16501 taaatattcc agaaaaaaat ctaggaaatg ttttacctaa cactggaaag aataccaaca
    16561 agtaatataa agttgtatat ttttaaataa attcaaaata atagtttata aataaaattt
    16621 ttggaaataa tattaatata attttaataa aaatttatat tttatactat gtaaaatatc
    16681 taatatattt ggtctgtagg ttaaataaaa gtacctttag accaaatata ttattaataa
    16741 cttaataaca tcttaaaact tatttattta tattatttac aacatccatt taataaatac
    16801 accataacct acagctgggt cattttcaat tgcatgtgac actgctccga ttattttatt
    16861 atcttgaact attggagtac cactcatacc ttgtacaata ccaccagttt gagctaaaag
    16921 ctttttatct gtaattttaa ttttaaaact tttactttct ggatgttttt ggttttctat
    16981 atctataatt tcaatattat attttttaca cttattaaag ttatcttgta aaattatttg
    17041 agcttttcct aatttaactt catctaaaga tgctacttta tattttttta aattggaaat
    17101 atcaaagtta ttaatttgac ctcttattcc aaaatcagta ttttctgtaa agctaccaat
    17161 aatattttct cgttttgcat ttatacatcc aacactacct ttataagatt tttctatatt
    17221 aaggtgctta gttgtagaaa ttgaacctgt tttaataggt atttttcttg cattaccaac
    17281 acttattgga tgacctacag ctccaaactc tgatgtatct ggattgatat acgttaaagt
    17341 agcaaatcca gaaagtaaat tgttaaaact aattttttct aatatgtgtt tggtagtttt
    17401 cattgttata agttgtccac ctctatttaa taaaatagat acttgttttt cttctggtaa
    17461 agcatttaag gtattggcaa agtcactata tccatcaact tcagaattat ttacctttac
    17521 tatagcatca cccaatctaa atggagatgc ttctccagga tttctaacta tgatattttt
    17581 taattctgcg tcaatttgaa gtacgtttcc aattggtatt aaatattcag gttcattttt
    17641 ttgtaaattt tgtgcataaa ttaaattatt tgagaaaaaa tataataaaa ataaaaatgt
    17701 taaaacaatt gtaaattttg acttagctaa gttggttttt ttacttaaag tattattttt
    17761 aaaatgaaaa tttttaagtt gcataaaaca cctctttctt attaaattat tttaataata
    17821 gaattgaagt tttcttgctg cttctatatt atgttgtgca agaattatgt tttgatgctt
    17881 ggaaaactga ctcaataaca ccttagtttt cataaaaata aataaaataa atagtgtata
    17941 tgataaaata aatacatatt catataaata aaaataaaca ataactgtct agcataagaa
    18001 aggagcaaaa aatgaaaaaa tatagattgt tagttacttg tataattgcc atgggaatca
    18061 taattatagg aacatcaaat ccagttagca atttttacaa gactacaaat ttgattagtt
    18121 caggaaatat cacaaatgaa aaagcagata aagatgaaaa ttcaaacaaa aataataaag
    18181 ataaaaatga agacaaatct aattctaaaa gtaataaaga taagtcatca gaggacaaat
    18241 cgtcagataa aaaaaataaa attcaaaaaa ataaaaaact tttaatttgt atagacccag
    18301 ggcatcaagg aaaaggagat agcaatttag aaccagtagc tccaggttct tcctctaaaa
    18361 aagcgagagt atcttcagga acagagggta ttgctacaaa aaaaccagaa tatgttctaa
    18421 acttagaagc atctcttgtt ttaaagagta tattagaatc taaaggttat aatgtaataa
    18481 tgactagaga gacacatgat gtaaatataa gtaattcaga gagagcaata cttgctaatg
    18541 ataaaaaagc agatatggtt gtaagaatac atgcagatag tttaaataat tcttcaaaaa
    18601 ctggagcatc tatattgatt cctgaaaaag atggaaaata tacagctcct atatatgaag
    18661 agagtaataa atgtgctgaa tttatcaaac agaatatgga acaatcaggt atacaaatca
    18721 atggaatcgt tcaaagaggt gatttgactg gatttaactg gtcaaaagta ccagccgtat
    18781 tagtagaaat gggatttatg agtaactata atgaagacca aatgatgtca aatccagact
    18841 accaaagaaa aatgatgcag tgtatagctg atggattgga tgcgtatttt aaataagata
    18901 tgaatagaga aaaagttagg ttggtattat tttcctaatt tttatctcta ttttttattg
    18961 tacataatgc aaagaagaag tttattttag gttaaattgt cgtaaatata actaaaaata
    19021 ttgggaatac ttgatttaag tttaaaaaga atatattata gtatagaatg tgtaaaattt
    19081 ttttgagagg tgttgaaatg ctagtagtag aaaatgtgag tcatggattt ggtgcgagaa
    19141 caatattaga aaatgtatcc tttagactta gaaaaggtga acatattgca ctagttggtg
    19201 ctaatggaga aggaaaatcg agttttttaa atataataac aaagaagctt atgccagatg
    19261 ctggaaatat aaaatggtct tcaagagcta cagtaggtta cttagaccaa catacggtat
    19321 taagcaagga aaaaactata agagaagtgc ttagagaggc ttttaagcat atgtttgact
    19381 tagagcaaga aatgattgct atgtatgaca aaatgggaga agctagtgat gatgaaatga
    19441 gtaagcttct tgaagaaaca gcagagatac aaactatact tgaaaatagt ggtttttata
    19501 tgatagatgc aaagatacaa gaagttgcaa atggtcttgg tcttggagaa attggtcttg
    19561 ataaagatgt aactgactta agtggagggc aaagaacaaa agtacttctt actaaacttc
    19621 tacttgaaaa tccaactatt cttatattgg atgagcctac aaactattta gacgaagagc
    19681 atataacatg gcttactaag taccttcaag agtatgagaa tagttttgtc ttagtttctc
    19741 atgatattga atttataaat aatacatgta atgtaatata tcatatggaa aatggagagt
    19801 taaatagata taaaggaaat tatgatgaat ttgtaagact taatgatata aagaaacgtc
    19861 aagaagaaca agcttatgat aaacaagttg aagaaagaaa aagactagag gattttgtag
    19921 ctagaaataa agctagagta gcaactagag gaatggctaa cagtagacaa aagcaacttg
    19981 ataagatgga aatattagaa agaccaaaag aaaaaataaa acctactttt gcttttaaag
    20041 atgctagagc agctagtaaa ataatttttg aaacagagaa tttagtttta gggtatgatg
    20101 aagcattgac aaaaccactt aatttccatt tagaaagagg aaaaaagatt gccttaaaag
    20161 gaatgaatgg tattgggaaa tctactctat taaaaacttt acttggaata ataaaaccat
    20221 ttgaaggaaa tgttaaatta ggtgactatt tggaagttgg atattttgaa caagagagtt
    20281 caagggaaaa tagtaataca cctatggatg aagtttggag tgaatttcca gggcttacaa
    20341 actttgaagt tagacaggct cttgcaaaat gtggacttac aaatgaacat ataacgagtc
    20401 aaatgagagt attaagtggt ggagaagctg ctaaggttag actttgcaaa gtaatgttaa
    20461 aaaatataaa tttcttagta ttagatgagc ctacaaatca tttagatgtt gaggcaaaag
    20521 atgaattgaa gaaggctatc aaagagttta agggaacagt tcttttagta tgccatgagc
    20581 cagaatttta ttcagaaatt gttgatgatg tatggaatat agaagatttt accactaaaa
    20641 tcgtgtagtg atttaactta ttgctggggg gatttcatga aaaagtttct aaatgtactt
    20701 ttttcagttt gtattagtat tgttataata gtaggtgtta ttaattttac tgttggattt
    20761 aaacaacttt attattttga cattgattac ttaaatatat cagagttatc tggtttatct
    20821 gaagatgata taaaattgaa ctacgattat ctaattgatt ataacttaaa taagaatgtg
    20881 tctgagttca agttaccaac attaaaatct tctccacaag ggaagataca ttttgaagaa
    20941 gtcaggaata tatttcaaaa tataaataaa ttagctaaat tattattggt agttttttta
    21001 gtaggaatta tattgagtgt aaaaaataaa aatataaaaa tcttgaaaac tacatcaata
    21061 acacttataa ttatgccatt attattaaca gttccaattt tattaaattt tgaaaaatca
    21121 tttattattt ttcataaatt ttatatctaa ttttcaatta tccgcataaa cactatacat
    21181 tcaagcattt tgaagtatag aaaaacactc atcttaccac gaatttacca cgattgaatg
    21241 agccttgata tgaccgtaaa actactaagg gagatagcac gaaactgtgt atctcccgat
    21301 ttttttatac agttgattac ttcactccga tttcaaattt caatattgct ttcatcatgt
    21361 ctgtatgaat ttctcctttt agttcttcat caacctgcat aatgatttta ccactttcag
    21421 agtggtaaaa aggacgcaag cataatttag aaatataacc gtcataaaac ttcaaaatct
    21481 ctttaactgc catttcatct ccgcttgacg ctttgcaaat caattcaaaa gagggatagc
    21541 cataatcttt actcatttct ttacttccct tcgctcaaaa gcatttttaa cttccttagt
    21601 cctctagttc ttctactgca aatagcagaa cgtgatacat ggtacagttc tgaaattttt
    21661 ctgtcgttca ttccttgaaa ataacgtaat aaaatcgcac tacgctgttt ttctgacagt
    21721 ctatgtaaaa ctgtaccaag tgtttcatca gatacataaa ttgtaaagtg caagacttta
    21781 aatgatacac aatcataaaa acaggtatca atcgttccac gttcaacttg tttcgtttcg
    21841 gctatttcac aaaacaatac ttcacgttta gaatgtcttg caagctgtct gtttcgactt
    21901 ttcactttgt tcttaatgac aatcagcatt aaagaattga actgtaatct gacgatatgc
    21961 tcgaaagaag atgtcctcat aatctcaccc cctttctgct aatgctgaaa tatataaacg
    22021 gaataccgtt tatacccttt agaaatacag aaaaatggta agaaaaaagc ccacacaaaa
    22081 catatatttg tgcgagcctt aaatactgca atattactct ttcttttata acactatcct
    22141 tttagcagat ttcaaatttt cttttatata ttgtttttag cctaacatac tatttaaccc
    22201 cttgtattat atctctaact tttgaaaaat tctttttgaa tatattgaaa tcatgattga
    22261 agcaatagaa gctacaaaca taacaaccca tgtttcttgt ataaatacat cgaataaaat
    22321 accgtaaacc atttgtccaa taggttgacc gcacatagca actgctacca gcgtagccat
    22381 tatctttcct actaattgcg gtggtgtttg tgtctgaaca agagtgtaaa tttgaacaac
    22441 aaacatagta gatacaccca tagccacaaa gcacatcact gtaactaccc agtaggaaac
    22501 tattgcaggc aattctaaaa atagcgaaat tcccataagt aaaacagcag tagaatttca
    22561 cgtttcttgt ctggcaactc acgtaatgct tcactcaaca aatcattttc aacgcctact
    22621 gataacccat tgagtgtaaa aatctgaaag tcagttgaat agttatctgt tgtcgcaaac
    22681 tggctaacaa gataatcgcc aacatccgaa aaggacacct cacgctttgc aatccttgaa
    22741 agataaagca tataattctt tcgctcgtct tccatagcac gtttacagat atagtcaaac
    22801 tgattttcta ttgtggtctg aaaagaagat ggtttcatgt ttctcacccc ctttctgtct
    22861 aggaaaggaa gtgagccttg ctcgtttatc tcctttcact cttagtccca atgtgaaagg
    22921 gggatttgtt gcattactga taaataaact ttgtaaaaaa gttctgaata gccaaaaaag
    22981 catataaaca gatttatttc tctgtttaca tgcttctgtt attctatcta tatgatttat
    23041 aaaaccacat tggtggacgt acttatctat tgcagataga cgactttttt tgacaagaac
    23101 ccaatgtaag gaaatttatt gtatatgatg tacttcatgg cgacgttgac ctccaacaaa
    23161 ccgccatttg gaagtaatat acaatatttt aacagcgtaa atagcactac catataacgg
    23221 ttttttttat tggcgtttag tagtgctttt tattaaatat aaacctataa accatataac
    23281 acgtttttct atacctgttt ttaattcagt aggaacaata aaatgtatag aggtggtcta
    23341 ctatgcgtaa aaaagaagat aaatatgatt ttagagcctt tggtttagcc attaaagaag
    23401 ctcgattgaa acgaggttta actcgtgaac aagtgggagc attgattgaa attgacccac
    23461 ggtacttaac taatattgaa aataaagggc aacaccccag catacaagtt ctttatgacc
    23521 ttgtatcgtt acttcatgtt tccgttgatg aatttttctt acctgctaat aacttggtaa
    23581 aaagcacccg acgattacag atagagaaat acatggatag ctttacagac aaagaactat
    23641 ccttaatgga atctttagcc agcggtatca acgaagcaag aaacatcgaa gactaattaa
    23701 aagaatccat acataacgga aagagccgat aaaatgagat tgtattaatc tcattttatc
    23761 ggctctgcgt ctttgcgtct ggctctgtaa tcacagttac tttgaactgc tttatttcaa
    23821 ttaaattttc ttgtctgcat ttcggacaat agagggggaa tttttttaat tcagtatctt
    23881 cccttatctt taatcgtgtt ttatttccac atacaggaca caatatccac ttgtagttta
    23941 taataactat ctcctccttt acactttaat tcaaatcttt attaaaaaat atttcatctt
    24001 atttaacaag aaaccatatt tatataacaa cataaaatac actaagttat tttattgaac
    24061 atatatcgta ctttatctat ccgactattt ggacgacggg gctggcaaac aggttcaccg
    24121 gtagtaacat ggtacccttt taactctgtt aaacaaacac tacgtccatt tgtaaagaaa
    24181 gttaaatcac tacgatattc ttgaatacac cgagcaggga tttctccact aagaatgacc
    24241 tcattatttt tcaattgagt gtctacgatg ttcgcacaat atttaggagc atcgttgtat
    24301 gctcgtgaaa gatattcctg tggcgcataa attttaaaac taagatatgg ctctaacaat
    24361 tctgttccag ctttttttaa gacttgttcc aatacaatag gagcaagcat ccgaaaatct
    24421 gctggggtac taacagggct atagtataag ccatacttaa aacagatttt acagtccgtc
    24481 acattccaac catacaatcc ttgttcacag ccatagcgta tcccctccat aactgcattt
    24541 tgaaacgatt gatttaagta tccaagagaa accgagctct catactgtac tccgctccct
    24601 aatggaagct gtgctacaga tagaccaatg gaagcccaga aaggattcgg tggaacttcg
    24661 atgtgaatgg tatactctgc tttttttaac ggtctttcca tataaatgac tgtaggctct
    24721 tttatttcta tctccacatg atacttttct tgcaacagtg cactaatcac ttccatttgt
    24781 actttcccta agaaagaaag tataatttca tgtgtcgtag aatccacgta atatcgtaga
    24841 agcggatcac tatctgagat ttccaaaagg gcatcaagca acatttctct ctgttcaggt
    24901 ttactcggtt caacagttgt ttgtagtaga gggtgcggat tttcaatctt ttttctctgt
    24961 ggcaatagtt ttgtatctcc aagaacacta tttaacttca aaaactcatt ttgcaaaata
    25021 acaatttccc cggaataagc cttatcgatt ttacataatt caccatttat tgaagtatac
    25081 atttctgtaa tttttatttt ttccttttcc gatattctaa ccgaatctcg caaatgcagt
    25141 acgccactat aaagacgtat atatgcaaga cgctgtcttt tttccgaata ctcaattttg
    25201 aaaacttttc cgcaaagttc agactgacct cgatgtgttg atgaataaaa tttattcgta
    25261 atcacttcta taaggttatc aatccctata ttgttttttg cacttccgtg ataaacaggg
    25321 aacagggaac aattatgaaa tcttatgctt tcctcttgtt cgagttctaa tgcttccaat
    25381 aatttcccag acgtatattt ctctaaaagg tcatcgtttc cctctattac cgtatcccat
    25441 tgttcagatt cggtaaagtt cgtcacacac atattaggat acagttctac cttctgtttg
    25501 attacaattt cggcagaaag tttctcttta atatcctgat aaaccgttga taaatcaatt
    25561 ccattttggt caatcttatt gataaaaaag attgtgggaa tccccatttt cctaagtgca
    25621 tgaaataata tacgagtttg tgcttgtacg ccatcttttg cagaaatcag tagaattgcc
    25681 ccatctaaaa ctgataatga acgatatact tctgctaaga aatccatatg tcctggcgtg
    25741 tctatgatgt tcaccttcgt attttcccac tgaaaagagg ttattcctgt ctgaattgta
    25801 attcctctct gacgttctaa aagcgtatta tccgtcctcg ttgtaccttt gtccacgctt
    25861 cctaattctg taatcgctcc actgttatat aataagcttt ctgttaaggt agtttttccc
    25921 gcatcaacat gagctaaaac tccaatatta ataattttca tgtgattttc ctccattcaa
    25981 aagcccaaaa gggcataaaa atcccagtga taaatactct tatcactggg atttttatgc
    26041 ataaccatag gcatacaaag catacagata ttctccggat actttagaat cacatgataa
    26101 aggtattctt aaactgggta caaaaaacta agccctccta aaaaaggaca tccaattatt
    26161 tgttcccact atcaaattga cagtttattt aagaatacct tgccgcatat ttatcaactc
    26221 cttttaaata gatacttaaa taatagcacg taagagcata tttgtaaagg aatctccaat
    26281 tttttatcaa agagagtacg tgattacaaa atagctgtaa taatgtacca atatttgtta
    26341 ttctataatc ttccaattac tcccgttctt ttcaagtacc aaatcaaatt gagatacctg
    26401 cgttgccttt gcctgattta ccacaaatca gattttatcc ctttcttcct cttgattgcc
    26461 cacaacagaa aagaaaaagc cctgtcaaga gctttgccac cattggtggt gctttgcact
    26521 cttgatcggg ctttttgttt gctgtatctt ctcgcaagag gaaaaaagtt actcgtcctc
    26581 atcatcaaaa ttgttattcc ttaatacttc tcgtaacagt tccatatctt cttttgagtt
    26641 cgggtttatc attttcacga cttgataagg tgtcttatac ttatgtccct ctatgctttc
    26701 cccaaacata tccatactgt ataaatcatc atagcggtct aataattttt gaaacttcaa
    26761 atgctggata aattctttga ttgggtaaag gtcggacgct tcaatgcttt tcccgttgat
    26821 atagtctgta atatattccc gtaacttttc taactcatat tccagccatt cttcctcgct
    26881 gtcaaagaag ttatcatagt gtccatgttt cagttctgca tttagacgtt cttcggctct
    26941 taaaaactga cagacttcct tttcagattg attgacatac ttccattctc ccgacaacaa
    27001 ttcattgggc gtaacgtcca gcacttccat tatcttttcc agcgtttcat aggcaggata
    27061 gttcaaccct ctttcaatct tggaaaggct ctgcatattg ataccgattt tgtccgcaag
    27121 ttcctgttgt ttcattcccc taaattttct tatggtctgt atattatttc ctaaatggct
    27181 tattttcatt gcataaccct ccatatctcg ttatatcttc gctattataa gtctatcatg
    27241 cttaatatga tttgtaaagg caaaaaaaga tattgacaaa taagcatata agaattacta
    27301 tgttcttgta atcgaataag cacaatagaa tgaaatataa aaacattcaa aaagaaatac
    27361 ctatctgatt aaatccgtag atatgaatat cggttgaaat ggaacttgtt agaaaaggca
    27421 aaacagaact tgctgacaaa gtatttctga cacggtggcg gaagcctctc aggcttaccg
    27481 ccatgacacc ttgtgtcaag gggaagaaat gctttgtcgg ctggcgagcc tgcgagcctt
    27541 gtctgtgccc ccgttatcta acaggggggc actatttcac aaaagacaag tcaaaaacca
    27601 tacaacccca aagctgtaag gagtaatgag gagttttaag aagatagtaa tttcacattc
    27661 ttttgaatag tggtttacag gtatttcaag gctattgtgg gattggagga atacaatgaa
    27721 caatttagaa tttgcacttg aaatgaagaa taaacgtctt gcaagcggtc tttcacaagg
    27781 agaacttgca agtcttaccc atgtatcaag atatagtatc aaccgctttg agaacggaaa
    27841 agccaacgcc agcaaggaaa cacaaaatat tatcctgcgt tgtctgaatt actatatctg
    27901 cgataagcct ttttatctgc tcgttgatta tctgtctgtc cgttttccaa cgactgacgc
    27961 attggaaatt atccgaaagg tgcttggcat gaaagcagat tattttatcc attatgacta
    28021 tggatattat ggctataaag agcattacgc ctacggagaa atcaaggtta tggcttctga
    28081 tgatgaacac atgggcgtat ttttggaatt aaaaggggca ggctcacgca atatggaata
    28141 tgttttacag gcacagaaca gggattggta ttcattcttg aaccgctgtc ttgactgtgg
    28201 cggtgttatc cgacgttttg acttggcaat caacgatatg tgcggtctgc tggatattcc
    28261 cgttttatct gaaaaataca aaaatggcgg tgcggattgt cgctgtaaaa actatgaaaa
    28321 tgtgcaaggc ggtaaactaa gcggaaaaaa ccgcaattta gcaagcaccc tttatatcgg
    28381 ctcaaaagca agcacaaaat atttctgcct gtatgaaaaa caaaaggaac aggcaactaa
    28441 aaagaaacat acggatatta tcaaccgttt tgaaattcgt ctgcgtgaca aaaaggcagt
    28501 acaggcagtt gaggaactgt tattgacgta taaccctcat gggctggtgt tttaccttat
    28561 tactgatttt gtgcaatttc ccgactatcc gctgtgggag atattcattt cccatgatag
    28621 tttacctttt gaaatgaacc ccgtacctgt caatatggaa cgcactctgc aatggctgga
    28681 aagacaggtc atgccgtcaa tcgtgatgat agaggaaatc gacaggctga caggctcaaa
    28741 ctacatgaaa atgattgatg aatgtaccca cctttctgaa aaacaggaaa tgcttgtgga
    28801 acaaatgtgt acggacatag cagacgtaat tgaaagtgag ggggtgtttt atgagtaatg
    28861 cacaggatat tcccgtatgg gaaaaataca cccttaccat tgaagaagcg tcaaagtatt
    28921 tccgtatcgg agaaaacaag ttaagacgct tggcagagga aaacaaggac gctggctggc
    28981 tcattatgaa tggcaaccgc atacagatta aacgacgaca gtttgaacag gttattgata
    29041 aattggacgc aatctaatgc aaatgagcct tgtatgtgtt atgatgaaca caagtcatat
    29101 caaggctctt tccaacaagg aaaggagcag acaccatgaa agaaaaaaga cgggataaca
    29161 aaggacgtat cctgcatact ggagagagcc aacgaacaga cggaaaatac ttgtataaat
    29221 atgtagacgc atttggaaat acaaaatatg tgtatgcttg gagattgaca cccacagacc
    29281 cgacaccaaa gggaaaacgg gaaaaaacct cacttcgtga actggaacag cagataagac
    29341 gggatattga ggacggtatc gacagcacag gcaagaaaat gacgctttgc caactctacg
    29401 ccaaacagaa cgaacagagg gcaaacgtga agaaaagcac aatgaaacaa cgggaacagc
    29461 tcatgcggtt attgaaagag gacaagttgg gtgctaggag cattgatacg ataaaaccct
    29521 ctgacgctaa ggaatgggcg ttacgcatga aagagaaagg cttttcctac aatactatta
    29581 acaaccataa acgctcgtta aaagcgtcat tctatatcgc catacaagac gattgtgtaa
    29641 ggaagaaccc ttttgatttc aagttaagtg aagtcctaga aaatgatacc aaagagaaag
    29701 tggcattgac agaggaacaa gaacaagccc tactgtcatt tattaagacg gacaacgtgt
    29761 atcataagta ttatgatgat gtgctgatac tgttaaagac tggacttcgt atctcggaac
    29821 tgtgcggact gacagtagcc gatattgatt tcaagaatga agttgtgatt atcgaccacc
    29881 agttattaaa gagcaaggaa cagggctatt atattgaaac gcctaaaaca aagaacggaa
    29941 caaggcaagt gccattaagc agagaaacaa tacaggcatt tcaacgggtt atgaaaaaac
    30001 gcccaaaggc agaaccattt gtgatagacg gacggagcaa ttttctgttt gtcaatcata
    30061 aaggcaagcc caaagttgcg attgattaca atgccttatt tgtccgtatg gtaaagaaat
    30121 acaacaagca acacaaggac aatcccttgc cacatatcac accgcatacg ctacgccata
    30181 cgttctgcac aaggctggca agcaagaaca tgaacccgaa agatttacag tatatcatgg
    30241 gacattcaaa catcagtatc acaatgaact ggtatgctca tgcgtccata gataccgcaa
    30301 aatcagaggt tcagcgtcta atcgcataga agtatttacc acgattttaa ccacgtttga
    30361 tagcgaaaat ataaaaagat agacctagat atgtgaggtt taccacaaaa gcaaaatgcc
    30421 cgtagagccg ataaaataag gctttgcgga catttgagaa gatataaaaa gatagtcaaa
    30481 aaggcatata taatttaaat gaaattatta tttagaaatg attattggat atttaatcca
    30541 aatttagacc cagttataaa tatattgcca gaggaatttt tttttcactc aggaatgatg
    30601 attttaatat taattttgtt agcaagtatc ttactatttg taatgtatag attatataaa
    30661 tctttcaaaa taaaataaga tagcaaaaac gaattatatt aaaggttata caataaaaat
    30721 agctatgtaa taatatttaa actaagagta gtcgataaat atttatgcat agctatttct
    30781 aatagaaatt actttttact agtgatttta actaaatctt gaaatttgcc cataatgtaa
    30841 ttgtaattat cttttttgtg aggtaacatg caactactgc aatctttgat acctttatct
    30901 gtatacttaa agtttccacc acagttttct cctaaagcat acaaaggaca atagcaaaat
    30961 agacagttaa actcttctgg tttattagtt ttatgacaag ggaaaaattc gcaatctttg
    31021 tgattaaaaa acttataatt ttcgcccata ttttcctcct aattaaataa aatttaaatt
    31081 ttttatacta tataagattt tggtgataat ataattatac taaataattt tatgaatagt
    31141 cgataatata gtattattaa tcatagtatt aatggtataa ttagtcaaca gaaaaataat
    31201 gtaaaaatta tgtaagtgta ttttgtaatt agaatatgtt ttataacaaa aaatgaggtg
    31261 attaagtgaa agaaattcaa gaaaaagcac ttcttgtagg tctgaatttg actacaatag
    31321 tgaaaaaaaa tgatgatata gacactagtg aatctatgga agaattaaaa gagctaacaa
    31381 aagctgctgg ggcagaagtt gtaggtagct taattcaaaa taaacattct gtagatgcag
    31441 cttattatat aggaaaaggt aaagtagaag aaataagagc ctatagtgac tctttagatg
    31501 ctactttagt aatttttaat gatgaattat ctggtgctca aatcagaaat atagagaatg
    31561 ttgttggaag aaaagtaata gatagaacta ctttaatttt agatatattt gctcaaagag
    31621 cacttagtaa agaaggtaaa ttacaagttg aattagcaca attaaaatat agattgccac
    31681 gactttatgg aatgggtggt gagatgagta gaacaggtgc agggattggt actagaggtc
    31741 ctggagaaca aaaactagaa atagataaga gacatatact taataaagca gcagacataa
    31801 ggcgtgaact taaagaagta aaaaagaata gggagacaca gagagttaag cgtttaaagt
    31861 caaatatacc gattgtagca cttgttgggt atacaaatgc aggaaaatct actcttttga
    31921 acgaattaat aaagacacac aaggattatg aacaagaaaa agaagttttt gtaaaagata
    31981 tgctttttgc aactttggat gtaactctaa gaaaggctct tttgccgaat aaaaaagaat
    32041 ttttagtagt agatactgtt ggatttgtaa gtaaacttcc ccatgattta gtagaggcgt
    32101 ttaaagcaac attggaagaa gtacagtatg cagatttaat tttacatgta attgatgcga
    32161 caaatactag ttatgaattg caaaaaagta cgactgaagg tgtattaaaa gaacttggtg
    32221 taaatgataa aaaacatata cttgtatata ataaagtgga taagctagaa ttggatatat
    32281 atcctaaaag tcaagaagat attgtgtata tttctgcaaa acaaggcata aatatggata
    32341 agctattaaa tatgatagaa attgctttaa tggaaaatac ttattcagta agcttgatgt
    32401 taccttatga gagaggtgat atatttagta gaataaaaga taaatataat gtggagaatt
    32461 ttgagtatgg ggaaaatggc ataacgctag atgtaaactt cgatgaagaa gattttaata
    32521 tctatagaga gtacatacta gaaaaatagg ttgaatatgg atataaattg ggaaaatata
    32581 gataatcttg aagattattt tataacctat cttctttata aagaatctaa aacagtatct
    32641 caaattagta aaattagaaa tatttcaagt actgaagcag gtgagcaact tatacaagca
    32701 aaattaaaaa taaaggaaat gcaaaaagat gattttgagg catctaagga tattttagat
    32761 aaatttttag aactagataa aattaagaga cttgatttta tggatagctt agatgacgaa
    32821 aaaatggtat actttaagag aaaggttttc aaaagaatcc ttgtggaaaa aaatgctgaa
    32881 gatttaattg ttttaatttg ggcgacaggt gagctaaaag atgatagatt cttaaagttg
    32941 cttcatcagc tcacaaacca cagacactca gatattagaa gaataactta ttcagcaatc
    33001 agaaagattg aatcaccaag tagtagagaa gtactgcaaa aaggtctcta cgataaaaat
    33061 gcacaaacta gacagtattg tgcaaaggct ctttcaaaac taggggatga aaacagttta
    33121 aagattttac agcagttgaa agacaagaat aagaattttg aaaaagaata tgtgcttaga
    33181 gcttatgacg aagccattaa gtcattggaa aatgcaaaaa atttgaaaaa gtaatttttt
    33241 attaaagcaa tttgtttact taatgatgta tttctagagt ttaacaaggt aataaataaa
    33301 ttaatgggag gggtttcaaa tgatagtaag acgttgtgca ggtggagtag tgttttatgc
    33361 taataaagta cttattgtaa aaaatgatag gggagaatgg acacttccaa aaggaaagat
    33421 acttggagga ggacttccat atgagagtgc tgttcaaaga gttaaagtag aaactggcat
    33481 agatgctaaa atgatagatg tggctggcga tactatgtat gaatttttct caagaagtag
    33541 acaacaagaa gtttgtaatg caataatgtg gtatgttatg gaagcttgta acactaattg
    33601 tgtacttgct cctgaatttc aagaaggtgg attttataaa gtaaaggatg ctttagatat
    33661 gttatcacat cataaagagc aagctttagt agaagtatct tataaaaagt ttaaggaatt
    33721 aaagaaatta gtttcagagg gcgatgatgt tccagcaaat taattgtgaa tttagaggat
    33781 tctgaggaag ggatagcccc ttcctttttt aattgaagca gttttaagcg taaattatat
    33841 agtctcttta aattatgatt tatcaattta gagctttagt agtttatatt taaaatcagt
    33901 aagatatatt taaaataaaa attaaaaagt atacaatttt attatataat tgtcttatga
    33961 tattgattaa agaagtatta aaagtccatt tatttttaaa tagaataatt ttatagatat
    34021 ataatttgat gtgtatatta gaaaatgatt aaaataggag gaaatacaat gagcaattac
    34081 aggacattac atgaatttgg aacagatgaa ataactattg aaaagtctgt ttttattgga
    34141 tatgctaagc ctataaagag tgaagaagaa gcattagagt ttataaatga aataaagaaa
    34201 aagcataaag atgcaactca caatgtgtgg gcttatactg taggtaaaaa tatgaatata
    34261 caaagatata gtgatgatgg agaaccacaa ggaacagctg gaatacctac attagaggtt
    34321 ataaaaaaag aagatttgag agatgtagtg gttgttgtta ctaggtattt tggaggaaca
    34381 aaattaggtg caggcggtct agttagagct tatacaaaag gtgctaaatt gggacttgaa
    34441 gcaggtaaga taatttataa ggtaatgtat caagaagtta aggttaagat agactatact
    34501 caacttggaa aagtgcaaaa tgagttaatg aatttggggt attttataaa agatactgta
    34561 tatgaggata atgttgagat agtagtgtat tcaagattag aagatgtaga gaaattatca
    34621 gaaaaaatga ttgatataac aaatggaaca ggaaaaataa ttttaggaga ggaattttat
    34681 ttgtctgaac aaaatggaga aattttaata taatctaaaa ggttattaga atagttaata
    34741 cctcaaatag ccaattagta tttttaagtg aaaagccatt aaattgattt aatctaaatc
    34801 aatttaatgg ctttttatcg gattttgcac agaatccttt ttttacttca aataaaccga
    34861 ctaaaagtaa aaatatccca aatatttttt ttaatatatc tgaagacaga taattagcta
    34921 atagtgaacc aaatacagct cctaaaaccc caaacacagc tataggtata accaatttaa
    34981 aaattacatt tttatttttt atatgtatag caagtgctat aagtgtcata gggatagatg
    35041 aaagtaaatt tacgctttgt gctattttag tgtctatgcc agcaagtaaa acgagtgcag
    35101 gtataaggat tgttcctcca cccattccca ttcctccaat aattcctgca aaaaatccaa
    35161 ttagagcaaa taacattaaa acaccatcct taatgctgca attatcataa ttattccaaa
    35221 agaaattcta agaaactttc cagtaacctt atttagtaat ttagctccta taataccacc
    35281 aagaatactt ccaactgcaa ctttaattgt taagttaaca tcataagtac ctttagatac
    35341 atataaaaca gaacttgctg tcgttaagaa tattattata gaaagagcag ttgcatgaga
    35401 tttatgttct tctaccttaa cgatgtcatt taatattgga actaaaagag tacctcctcc
    35461 agaaccaaaa actccattta taaatcctgt aaaaactcca attatcgtat tttttaagtt
    35521 aaaatcaaag tattttttct ttaaatcatc agtttttttc ataaaaatca ccttctgaaa
    35581 tagttttacc aaaataggca aattatattt atataaaata agattaaata taatctttca
    35641 tgtttgttta attttgcata aaaaaaaaca tattaaaaca acatattaat atatggtata
    35701 atatattaaa acaaagtagc aaatttgaga ggagataaca atgtcaaata taaaaataca
    35761 aatagacaaa actgtagaat ggcttataaa taaggttaat gaggcaaatg caaaaggatt
    35821 aattgttggt gtatctggag gaattgattc ggcagtagtt gctaatttaa ttaaaaaggc
    35881 atttccagaa aactctatgg gagttataat gagcataaaa agtaatcctc aagatagaga
    35941 agatgcactt aaggttatag agggatgtga tatagaatac cttgatttag accttataga
    36001 accacaaagt gctatattag acatggtagt aggaaattta aaagataaac atttatatag
    36061 agcagaatat ttaaagatga cagatgcgaa cttaagagca agagtaagaa tgagtacaat
    36121 ttatacaatt gctaacaatc taggatattt agttgttggt acagacaatg ctgcagaaat
    36181 acacacagga tattttacta aatttggtga tggtggagtt gatattttac ctattgcaaa
    36241 tttaactaaa ggagaagtat atgaatgggc aaaagagctt ggtgttcatg aagatttaat
    36301 aaacaaagct ccttcagcag gtctttggga aggtcaaaca gatgaagatg aaatgggaac
    36361 tacttacaat atgatagatg ctgtgttaga aggtagattg gatgaagttc ctaaaagaga
    36421 ccaagagata atagaaagac ttcatagatt aagtgaacac aagagaaaaa cgcctgcaca
    36481 acctcctaag ttctaattta ctatttataa gatttgtgat aaaatttaca agtgatgaaa
    36541 attagaataa ttaattgtac gtattaagga gtggaaatat gggacgtata ggtaatataa
    36601 ttaatagaaa aggtaaacaa gatgctcaaa gagcaaagat atttactaaa catgctagag
    36661 caatagcagt tgcagctaaa gaaggtggag cagacccaga gtacaatgca gcgttaaaaa
    36721 cagctataga aaaagctaag gcagataata tgccaaatga taatatagat agagctatcg
    36781 ctaaaggtgc tggagcaggc gctggagaag actatgaaac tatagtttat gaaggatatg
    36841 gacctggtgg agttgctgtt atagtagaaa ctttaactga caacaaaaac agaactgctg
    36901 gtaacgtaag atactatttt gacaaaaacg gaggaaactt aggaactagt ggatgtgtgt
    36961 cttttatgtt tgataaaaaa ggacaaatat tagttggttt aggagatgga gtttcagaag
    37021 aagaattgat ggatgttgca ttagaagcag gagctgaaga tttcataaca gaagaagatg
    37081 gttatgaaat aataactaca ccagaagatt tttctagtgt tcgtgatgag ttaaaagcta
    37141 aaggatatga gtttatatct gctgatgtga agatgatacc tcaaactacg actgtattga
    37201 ctgaagaatc tcatttaaaa atgatgaata aattagttga tatgcttgaa gaagatgatg
    37261 atgttcaaga tatatatcat aactgggaag tagaataaat agtataagca tattgaaatt
    37321 tataagcatt gaatcaattt taacatgtga taaattttat agaataagaa attactaaaa
    37381 tagacatacg cacctctaac ctatatttgc ataataatat gtaagtatag gtaaggggtg
    37441 tttttatatt tataggttaa gaaatttaaa gtaaattttg agctggactt gattgtctat
    37501 aaataattga tgggtatata acttgttgct gaataccatt tatacgccca gttactgtat
    37561 caataatcat cctaagacta cgttctgctg tctcttccat ttttaaatct ataactgtca
    37621 aaggaggaat acttcttgcc attagtcgtg aaggtccatt acttgctgca aatatttgaa
    37681 tatcctctcc aattacaatt ccagattcat gaaatgcatt catcatacca agagctacaa
    37741 catcatgatt acaaaaaatt acttttttta gtgaattttt tgcaagcatt ttttgagcaa
    37801 tatcatatcc actatctatt ttattagaac aataatatat agaatctgat agatgtattc
    37861 catgttcttt acatgttttt aaaaaagatt taccccttaa agtcatacat gtaaaggaag
    37921 ttgggttgaa tacaacagca atatcatttt taccattttg aatagcatgt aaagctgcta
    37981 tacgaccagt ttcctcatta tcaatagata cacttgaaaa accaggtatt tcacgattta
    38041 caacaactac aggaatttta ggtttatttt ttactagata ttctatatca tcagcattga
    38101 tacctgttaa aacaattcca tcataataat tatttgcaaa aaagtattca tcatcacata
    38161 gatgaccaac tttgtaaggt cgtatgatga tatttatgtt taaatgttct aaagaaatta
    38221 tgtggtttat tgcttgaagt atattggttg atgccaactc aaatccctca tcctgccaat
    38281 aaaaagctat tttaatatta ttatgtttaa taggagtaga gcgtttatat ccaagcttat
    38341 cagctgaatt taatataagc tcttgtgtat gtagcggaat cctgcgttca tttcctttac
    38401 cacttaagac gtacgagaca gttgctgaag aaagaccaca gtcttttgca atatctttga
    38461 ttgttgccat gataaaatcc tccttaaata gttgcttaaa tttgcttata ccaataatct
    38521 taacatatat tcaactaaag aacaatattc tacaaggtgc atattttaca ggattagaat
    38581 aaataaattt aaaaaaactt cttacttatg ttgacataat ttagtttata ggattataat
    38641 atgcttaaat aagcttatta ttaactcaaa ttaagcaaag ttaagcagga acatgcaatg
    38701 ctagcttgca atgtgactgt aaagggggaa aaggtatgag taaggtaaat atatttgaag
    38761 ttggtcctag agatggattt caaaacctga aagagttttt agaaactgat aaaaagctta
    38821 agattattga tggtcttatt gcttcaggga ttaaacaact tgaaattagt tcatttgtaa
    38881 gcccaaaagc aatacctcag atgaaagatg caaaagaagt agcaacttat tgtgtagaaa
    38941 aatatcctga tgtgaaactt tatgcattag ttccaaattt atatggtgct aaagttgcat
    39001 gggagtgtgg tataagagat atatcctatg ttatatcttt gagtgaaact cataataaaa
    39061 aaaatataaa tcgtacccat gaagagtcta ttgatgagct taaaaaaata atgaatactt
    39121 atccagacat gaatatatgt attggaatgg ctactgtatt tgggtgtcct tttgaaggtt
    39181 taccaaaaat tgaagatgcc ataagatttg ctaaacgcct ttgggaaaac ggtatcaggg
    39241 agataaatct agcagataca atagggattg ctgaccctaa gcaagtaaga gaaactatta
    39301 gtgcattagt tgaagcttta ccagagtgca gatggcaggt acatattcat gatactagaa
    39361 atatgggaat ggttaatact cttgtggcta ttgaatctgg aattactact gttcagtcta
    39421 cacttggagg attaggagga tgcccatttg ctcctggagc atctggcaat actgcaactg
    39481 aagatttagt atatatgctt gaacgtatgg ggtatgatac aggagttgat tttgttaaac
    39541 ttcttgaatt atcaaagtat cagaagagtt ttgtaaatgg agtatatagt ggtcatcatg
    39601 taaatataaa gtctgatagt tgtaattgtt agttctattg attaatcgat taaaaaaata
    39661 tgttgattaa aaaaatatgc tgattggtaa aatagattta ttgataaaaa agataaatta
    39721 taaaatacat tatctaataa aacaaataaa aaaattgagg gggattagta tggatattat
    39781 agctttactt ttatttttag gagttattat tattgcattt gtacgtaaga ataatgcagg
    39841 tattttggct ctagctattg gtgtcatagc tgttagaatt tttggaatgg atgataaaga
    39901 actttatgga gctataagca actcaatgtt tactacactt gttggtataa cactactctt
    39961 tgcaatagtg aactcaacag gagcattaaa gcttgttgca gaaaaaattg tagctgcttc
    40021 tggtaaacgt gtttggctta tacctatagc agtttttata gcaggatttg ttgttgctgg
    40081 tgttggacct ggggcaattc cagcacttgc aattatccca gcaatggctg ttcctgtagc
    40141 cataacggtt ggttataatc ctgtaatgct tgcacttata ggtgaatgtg gattaatggc
    40201 aggtcgtatg actcctatta ctccagaagg tcaaattata acaaccgttg cagaaggggt
    40261 tggaattgaa aatgttatgc ctactatctt agcctgtcaa actctttcta caattgtatt
    40321 ttcaatagta ttgtttataa ttttcaaagg atataaactt aaaaaaccta taaatgttat
    40381 agatagtaag caaatagaaa aatttaatat aaagcagata atttctctaa taagcatagt
    40441 agttatgatt gcttttatca taatttttga tatgaatgtt gggcttgcag cttttgcagt
    40501 ttcagctgta cttatttttt tcaatattgc tgatgaagga gaatgtatca aatcaattcc
    40561 atggagcacg atagtaatgg ttcttggagt aggtgcaatg atgacaatcg tagatgcagc
    40621 aggaggtatt gacttgatga gtaatgcatt atcatcactg atgaatagta aaacagctac
    40681 tccaattatg agtatttcag caggacttat gtctatggtt agttctgctt tagcagtagt
    40741 ttatccaact atgatgccta tgtgtgttga tatagctaag gcagttggag gagtagaccc
    40801 actagcactt attgctgcag tcggtgttgg aggttctctt gctggtgtaa gcccactttc
    40861 tactggtggg gcattgattt tagcagctat gggttcaagt aagaaagact ttaataagga
    40921 agaacaaaat aaggtttttg tacagctttt cattatgagt gcagttggct tattggttat
    40981 tgcagtagta tcaatattat catttaatgc aataacacat ttaatgaact aattataata
    41041 actgaaaata attcattaaa tttaattttt aatattaatc aatataatat aatttggagg
    41101 ggaagttatg aaaaaaggag cattaagcaa tataaaggta cttgacctta caagagttct
    41161 tgcaggtcca tattgtacaa tgatgttggc ggattttgga gctgatgtta taaaaataga
    41221 gatgccaaga aaaggtgatg atacaagagg ttttggacct tttgtaaatg gagagagttt
    41281 atactatgca aatataaata gaaataaaaa aggtatcact ctaaacctta aatcagaaga
    41341 aggaaaaaat atatttttag aaatggtaaa acatgctgat gttgtagtag aaaattacag
    41401 accaggtgta atggaaaagt taggtctggg ttatgatgag ttggctaaag ttaacaatca
    41461 aataatttat ggagctgtat caggatttgg atgttatgga ccatattcag aacgtccagg
    41521 ttatgatatt attgcacagg caatgggtgg tcttatgagt ataacagggc aagaaggagg
    41581 agaaccaacg agagttggta atgctatggg tgatgtacta ggtggaatga atttaactat
    41641 tggtatactc acagcactca acgctagaaa aataatagga aaaggacaaa gagtagatgt
    41701 ttccctcgtt gattctgttg tatcgtctct cgaaactggt atacagagat actttgattc
    41761 aggacaacct gaacttatgg gtaatagata tgcttcagcc tatccttatg actcttttaa
    41821 ggcaagtgat ggaagttttg taataggctg tggtaatgac aaactttttg aaaagttatg
    41881 taaaaaagtt ctttttagag aagacctttt aatagatgag agatttaaaa caaatcttaa
    41941 gcgttgtgaa cattacaagg ctcttaaacc agaaatagaa aaatggtctg ttaagcatac
    42001 aataaaagaa gcagttgact taatatcaga ggctggagtt cctgctgctc ctatctataa
    42061 tcttgattgt gttacaacag atgaacatat agcaaaagca agagaaatga ttgtagatat
    42121 tagtcatcct attataggaa atatgaaagt caatggaaat ccagttaagt tgatgacaac
    42181 aaaagctaaa attgatatgc cagcaccatc tctaggggaa agtaacgagg agatttataa
    42241 tggttggctt ggttttgata gtgataaaat aaaagattta aaagaaaatg gagttatttg
    42301 attaaaaaat agctaaacac acttgtgact ttagtcatgg gaggttcagt tagaataata
    42361 tcaaaaaata ttaaatcaat actgtaaatc aaatatagaa ttgtcagaag catttaagat
    42421 gggaaaagct acttagacat tgagtctttg tggcttttcc tattttcatt aagaacttta
    42481 tattatcaga atagatatgt actaaactaa agtattaaca atttaaatta atagaaaata
    42541 aactacctaa ttatgttgaa taaagactac tttagtgaaa ataaacttat agagatgcta
    42601 tttaaattat tttaatggaa atatcaaaaa tgagactgca ttctcaaaaa tgagactgcg
    42661 ttttttaagt attttctcga aaatgagaca aaaatattgt tttatgagtt ttattgaaga
    42721 aaaattcttc tgtgaattac aatttaatca attttaaagt tgaaaattat taaaaattta
    42781 gtgaaattta tgtatatttc gtttatttta ttaaaaataa caatttttta ctaaaaataa
    42841 agaacttcaa tggtgattgg catagtactt gctattttat attaacaaga aatgtagaaa
    42901 aaataacaat gtataatggg gggaatatga tggaatctgt aatggaaaat ttgaacaatc
    42961 ttaaggtgga ggttaaggac aaagtctgtg ttattactat aaatagacct aaagctttaa
    43021 atgctcttaa tagtgacact cttagggaac tatcacaagt tattgatgta gtatcagaaa
    43081 atgaggcaat attaggagtt attattactg gagaaggtaa agtttttgta gccggtgctg
    43141 atatacgcca gatgcaaaac tataaaagtg aggaaggcag aaaatatgca ggttatgctc
    43201 agggaatttt tgataaaatt gaagctcttg agaaaacagt aatagcagca gttaatggat
    43261 atgcattagg tggtggatgt gaacttgcta tgagttgtga tattagaatt gcatcagaaa
    43321 aggctatatt tggacaacct gaagttaatt taggagttat tccatgtttt ggtggaactc
    43381 aaagattatc aagacttgtt ggaactggaa tagctaaaga gttaattttt acggggagac
    43441 aagtaaatgc agaagaagct aaatctattg ggcttattaa taaagtggtt ccaagtgatt
    43501 tacttttaga agagtctatg aagatgatga accaaatagt tgaaaaagcg ccaatagcaa
    43561 taagatatgc aaaagttgtt attaacaaag ggatagatat ggatttaaag aatgctcttg
    43621 aactagagaa agatattgca ggtttaactt ttgctacaag agataagcaa gaaggaatga
    43681 atgcatttat agaaaagaga aagccagttt ttgaaaataa gtagctatta taactaaatt
    43741 ggaacaatgt agaatatatt caaaatctaa atttcgtgaa aaaatacata tagtttaatt
    43801 ttaaaaggag ttaatttatg aatacgggag taattataag tttagtaggg attatcatag
    43861 ctctatctct tctagttgta atggttatga agggaataaa tatttttatt atagcaattg
    43921 tatgttcatc attagttgct ataacaggaa gcctaaatgt gtatgatgca cttaaagtgg
    43981 attatatgac aggatttgtt ggatttcttc aggcaaattt ctttattttc ctaacaggga
    44041 cattaatggg aaaaataatg gagattactg gtggagcaaa atctattgct aagatgattg
    44101 taagatggat tggtaaggat aaagcactac tttctattcc aatagcttgt ggaatattag
    44161 cctatggtgg agtaagtgtt ttcgttgtaa gttttgcagt gtttccgata gctttagaaa
    44221 tttttaaaga agctgatttg ccacgaagat ttataccagc agctttgact tttggatgct
    44281 caacttttgc tatggttgca ccaggggcac cacaaattca gaatattgtt ccagcatcaa
    44341 cattagggac agatattatg gccggagcag taaatggttt tatatcatgt gcagtaatgt
    44401 ttatagttgg aagtaccatt ttgtacaaaa tggtttcaaa agaaaaagcc aatggtggtc
    44461 attttatagc acatgaatca gatatatttg atgaagcaga agcaactaat tctaagagag
    44521 aaaatggtcc taatggtgta attgccttaa ttccattgat agtgtcaatt ttaataatta
    44581 atgtaaaagt taatggaaaa gcgatagtac caattgaggt gggagtattt attggagctt
    44641 tattagtata tttattgtta aataaatatc aagataatac taaaatagtt ggacatgttg
    44701 gtgatgcatg taaaactaca gtagtagcaa tatgtaatac ttgtgctgta gttgcatttg
    44761 gttcagtagt aaaatcagca gttggttttg acttcatagt taatgccatg actaatattc
    44821 ctggtcctcc tattgcaggg gctgcagttg gaactacagt tattgcaggt atttgtgggt
    44881 cagcttcagg tggactagga attgcagctc cacttcttgg accagtattt ttagccaagg
    44941 gtgtttccgc tgcagcatta actaggacta tggcaatttc atcagcagca ttagattcac
    45001 ttccacacaa tggatatatt gttactgtaa caaatggtct gtgtaaagaa acacataagg
    45061 atgcctatat gccaatattc tgggtaactg ttttaactcc gtttattgga accatagtag
    45121 cagtcctact gtttacaatg ttcccgggat tgccataaga gaaaagataa aaggtataaa
    45181 ttatattttg atattataaa atcaattttc aaaatatata caataaattt catgttttaa
    45241 tactataaat atgtatttaa aataacaaat tgaccatata aggaggaatt gaaagtgtta
    45301 aataaaccat tagagggagt taaggttatt gacctaacgt attttgtagc aggtccaggg
    45361 acttctaaaa tattagctga ttggggtgct gacgttatta aggtagagcc aagctttgga
    45421 gacccaggaa gaaagacagg ggcaacaatg acaatgccaa tagatgatta taataatcct
    45481 ttttacagca catataattc aaataaaaga ggtttgtcta taaatcttaa gagtgaaact
    45541 ggaattgaaa ttatggataa gcttttaagt gaagcaaacg tatttgtttc aagttataga
    45601 acaggagcat taaaaagact aggtcttgat tatgaatcat taagtaaaaa gcatccacac
    45661 cttatctggg gtcagataaa tggttttggc gattttggac ctgctaagga taatgcagga
    45721 tttgatacag ttgccttttg ggcaagaagt ggggctatgc ttgatatagc agaaaaagat
    45781 acaagtccaa taaatccacc tatagccttt ggagatgcaa caacttcttg tagtttatct
    45841 ggaggaatat gtgcagcttt gtaccagcaa gctaagactg gaaaaggaca aaaagtaatg
    45901 gcatctttat ttgggcaagc aatatggaat gcatcatctt tattagcatc tacacagttt
    45961 agtgatgagt atccaaaaac tagaaaaaat gctatttcac cagtaataaa ttcttatcgt
    46021 tgtaaggatg gaaagtggat attcttaagt attttagagc atgaaagata ttttgaggca
    46081 ctttgtagat tatttggaag agaagactta ataaaagaag agaaatttgc atcttcagta
    46141 gaaagtaaga aaaatgctac agaacttatt aatattttgg atggtgaatt tgcaaagttt
    46201 actcaaaatg agatggttga aaaacttact gctgctgata tagctcatga aaaaattcaa
    46261 catgttaatg atgtagtgac tgatgaacag gctattgcta ataactatat atatgagcat
    46321 acaagtaaaa atggaaataa gacaatgctt gcatccactc cagttaaatt tggaaatatt
    46381 gaagttaaca tgacttgtga tgctccactt ataggagaac attcagatga gatattgaga
    46441 gaacttggat acagtgattc tgatatagaa gctctaattg aatctggaat tgtaacaatg
    46501 aataaagaag catgtgaaat atgttaataa acatgtgaag tatgttaata aataggaggg
    46561 aattttatgg attttagatt aacagaagca caattaatgc ttcaaagagt agcaaaagaa
    46621 tttgcagaga atgaaatagc accaatagct gctgaaacag ataaaacagg tatttttcca
    46681 agggagcttt ttagcaaaat ggctaaaata ggatttaatg gcattggaac acctgtagag
    46741 tatagtggtt ctggagggac agatatagaa aaggtaattg ttgttactga gattgccaaa
    46801 aaatgtgcag catctgcagc aatattatca atacacacaa tatatgctca agctattttg
    46861 aaatttggta ctgaggaaca aaagaaaaaa taccttccaa tgatggctga aggtgggtgt
    46921 gtaggtgctt tcgccttaac tgaacctaat gctggttcag atgctgcaag agctgcaaca
    46981 actgcaatta ttgatgaaga aacggatgaa tatgttttaa atggaactaa gtgttttatt
    47041 tctggtggag gtcaagcaga atcattaata atatttgcac tgacagaccc atcaaaggga
    47101 ataaagggaa tgtctgctat cattgtcgac aaaggtactc caggtttttc aataggaaaa
    47161 attgaagaaa aaatgggtat tcatggttca gaaactgcag agttaatatt tgataactgt
    47221 agagttccaa agtctaactt attaggaaaa gaaggcaaag gatttaatat agctatgact
    47281 tgtttagatg gagcaagaat tggaattgga gctcaagctg taggaattgc tgaaggggct
    47341 ttagaagaaa gtatcaaata ttctaaagaa agagtccagt ttggcaagcc aatttcagcg
    47401 ttgcaaggta ttcaatggta tatagcagat atggcgacaa tggtggaatc agcaaaatta
    47461 ttagtatatt atgctgcaga tttgaaagct agaggagaaa aacacactaa agaagctgct
    47521 atggcaaaat acaatgcgtc aagtactgca agagaggtta caaatctagc ccttcaaatc
    47581 catggtggat atggatatat gaaggattat ccattagaga gaatgtacag agatgccaaa
    47641 ataacagaaa tttacgaagg tacttcagaa atacacaaag ttgttatttc aagagcagta
    47701 ctaggatagg aggaaaagaa tgaatatagt tgtttgctta aagcaagttc cagatactaa
    47761 tgaagttaaa ataaataaag agacaggtac tctaataaga gatggtgtac caagtataat
    47821 caatccagat gatagaaatg ctttagaaga agctctaaaa atgaaagatg aactaggagc
    47881 agtgattaag gttataagca tgggacctcc tcaagctaaa agtgctttaa aagaagcttt
    47941 ggcaatggga gctgatgaag cttatttaat ctcagataga gcttttggtg gttcagatac
    48001 ttgggctaca tctacaatta ttgctgctgc tatagaaaag gttggaaagt atgatgtaat
    48061 attctgcgga agacaagcta tagatggaga tacagctcag gttggaccag aggttgcaga
    48121 atttttaggg ataccacaag ttacttatgc aaaagaagta aaggttcaag atgacaaatt
    48181 actagtaact cgttatacag agacagggga ttatttaata gaagcaaaga tgccagtttt
    48241 attaactgct ataaaagagt taaacaatcc aagatatcca agtgtaaaag gaatcttaga
    48301 agcttataat aatggagatg cgaagattac tgtattaaca cttgcagatt tagatgttga
    48361 tacaactcaa attggattaa agggttcacc tacaaatgtt tataagtctt ttgcaccagt
    48421 taaagacaag cataatgaaa taatagaagg tataaataaa aaagaaaaag ctgagaaact
    48481 aatagaaata ctattcgatt tgaaactagt ataggagtgt taagatgatg agagcaaaag
    48541 ttaatcaagg tataaattta aatgattata atggtgtttg ggtaataggg gagcaaaggg
    48601 aaggcaaaat taatcctgtt acgatagaac ttattggtga aggaagaaag cttgctgacc
    48661 aattaggaaa agagcttgaa gttgtgatag ctggatatga agtagagaaa gaagtgaagg
    48721 aattacttca ctatagtgtt gataaagtat attacatcaa tgaccctctt cttaaagatt
    48781 tcactactga tggatatgca atttcaattg caaatttaat cgaaagaaaa aagccagagg
    48841 ttgtattggt tggtgctact tctataggaa gagatatagc gcctagaatt gcaggtaagg
    48901 ttggaacagg tctaactgct gactgtacaa aacttgaaat agattcaaca gataataagt
    48961 tattacaaac aagaccagca tttggtggaa atttaatggc cactattgtt tgtccaaaaa
    49021 atagaccaca gatgtcaaca gttcgtccag gagttatggc aaaagctgta agaaacgaat
    49081 cagagactgg aattttagaa gttgttactc cagaacttac tgaaaaaatg attagaacta
    49141 gattagtaga ggtacttcca caagaaaaga aatctgtaaa tctaactgat gctagaataa
    49201 tagtatcagg aggaagagga ttaaaaagag cagaaggatt tgagcttata aaagaattgg
    49261 ctgataaatt gggggcagag attggtgctt caagagcagc agtagattca gggtggatag
    49321 aacattctca tcaagtggga caaacaggaa ctactgttag accagaacta tacattgcat
    49381 gtggaatatc tggagcaata caacacttag caggtatgag tgattctaaa tatatagttg
    49441 ctataaataa agatgcaaaa gcccctattt ttagtatatg tgactatgga atagtaggag
    49501 atttatatga aattatacct gaaatgatag aatcattaaa taggtaactt ttagaaaaca
    49561 ttgaatatgt agaatgataa gtcttataat attgtattgt aagacttatt atttttgctg
    49621 aaggttatag tggggagatg aaacaatgaa agagcagtgg tataaggata tatttgcaag
    49681 aatattatct atgactgatg atggttttat tgttgtaaat acaagtggag taataataga
    49741 tattaatgat aaatattgtg actttttagg aaaagaaaga aaagatataa taggacaaaa
    49801 tatacaaagt attataccaa atacaaaaat gctagatgtt atgaaagata agtactgtga
    49861 agaaggagct atacatcatt attcaggtgg aaatacaaaa gaaaaaagtg taatagtaag
    49921 taggtcttat gtagaaaatg acaatggaga agtagttgca ggagtagctc aagttaaatt
    49981 tagattgcaa tcatttgatg tagctaaaaa attaatgtca gaatatatgg agctccaata
    50041 ttataaagag cagtttaagg ataactgcgg ttttgacaag ctcataggtg aaaatagaga
    50101 cttcatagaa cttaagaaaa caggtgtgaa agcttctaaa acaaactttc cagtactttt
    50161 aacgggtgaa acaggcacag gtaaagaagt ctttgctaga gcaattcaca ataatagcag
    50221 taggtcagat aaacctatgg ttagtataaa ctgcgctgca ataccagaag aattattaga
    50281 gtcagagcta tttggttatg acgaaggagc ttttacagga gcaaaaaagg gtggtaaaaa
    50341 aggtaagttt ttagttgcaa ataatggtac aatcttttta gacgagatag gtgacatgcc
    50401 tttgaccatg caagcaaaac ttttaagggt tcttcaggaa agtgagatag aaccagtggg
    50461 aggtcttaaa actataaaga tagatgtaag agtaatctct gccacaagaa agaatttaag
    50521 taaaatggtt gaagagggat tatttagaga agacctatac tatagattaa atgtaataaa
    50581 cattcatatg atggaattga aggacaggca agatgatatt ttattgctag caaattatat
    50641 attaaacaaa ttaaatgttg aatacaagga attgaaggtt ttaagtgata aggttaaaaa
    50701 ttgttttatt aactatactt ggccgggaaa tataagagaa ctacaaaatg taataaaaag
    50761 tgcctatgct gtaagtgatg atatggtcat tatgatgtgt gaccttccat ctaagatgga
    50821 taatatcagc agagtagctc aatgtaatgt ggatagcaat tgttcaattc atgaaatggt
    50881 tgagaattat gaaaaaagct taattattga tgtgttaagg aagtataatt ggaaatgttc
    50941 taaggcagca gaggttatgg gaatacacaa gagtctttta tataagaaaa taaaaaagta
    51001 tgaaattgaa ttaaataatt aagataactt gaattaaggc aatgctaaaa aaagcgccct
    51061 tattcaaagc gaactgtata aactgtttta tgcagttaaa acgtgtaaaa gtagatgtga
    51121 agtactaatg tcaatcatta gtacttttta ttgtatttat aattactatc tatatttcag
    51181 tatcttttga tatctaagat tattatgttt aatttaggat ataacaaaac cctcttagtt
    51241 attgacagtt ttttatattt taactgtcta ctaagagggg atagtttagt ttaaatttag
    51301 agtaaatttt atctagcatt tataaaaaat attttgaata gcttttttgt tatttagtca
    51361 taattttcta cttctttatc aagttctttg ccacaagaat cacacttata tatagcattg
    51421 tatccataat catattcatc aactattttc ttttgtctaa atacaccacc acactcacat
    51481 aggaaaccaa tttttataag tgtaacgata aattgtgatt ttataaattt tatatcatta
    51541 catttatcgt tagtgtaaaa tgtataaata taagagttat cgcactcatc tcttaattca
    51601 aatctttcaa tatatgtgtt attttttaat tcctcaaatt cttctttagt taaatatgat
    51661 ttttgttgca attcatgtaa acgcttaatt tggtccatta tttatatcct cccaataatt
    51721 ttagtatttt aagcttagat aaggaatcta agttttatta aatttatccc aaggaattat
    51781 ttaaatcata tttagtttta ttaattacaa catatataaa ttacacgaaa ataaaactaa
    51841 ttgtaaaaat aatatcctgt gaaaacctaa actactaacc ccttactaac ccgaaaacta
    51901 aaaaaagaaa atatatccaa atataagtga tatataaata aagatgtttt atataaattt
    51961 aactttaaat attctgacaa taatatatat aaatatatta tagttaaaat ataccacata
    52021 ttttgggcat tgtatactgg aattagagta attaatttat tttttaacat acaaatgatt
    52081 ttatgaaaaa aaacaagact caaaaatttt tatattcttt gatagaataa aattgagagt
    52141 aaatttattg aattttataa aatttataag gggtgagtct aagatatgca tgaagataaa
    52201 aatgatatat ttgaatcaat agatactgag gattttgata ataaaacaga agaagaatgt
    52261 ttagagctag taagaaaaaa tggattgaat ttaatataca taaaaaatca aacagaagag
    52321 atatgtctag aggctgttag acaaaattgt aatgcaataa aatgtgttca gaatcagaca
    52381 gaaaaaatat gtatagaagc agttaaacaa gattggagaa tgttagaatt tgtggaagag
    52441 tcaacagaag aaatttgcat gttggctatt aaccaagatg gaacagcatt aaaatatata
    52501 gaaaatcaga cagaggagtt atgcttaaga gccgttgaaa aaaatggtgc ggctttggag
    52561 tatgtaaaag aacaaacaga agaaatatgt atagaagcag ttagaaacag cgaatttgga
    52621 ttggcaagag tgaaaaatca aacagaaaaa atatgtatgg aagcagttaa gcattgtagc
    52681 tataatctaa aatgggtaga aaatcaaaca gaagaaatat gtatggaagc agtgagacaa
    52741 aatgggcttg atttgaaatt tgtaaaaaat caaacagaaa caatctgttt aagagcagta
    52801 agacaaaatg gaatggcatt agaatttgta aaggaacaga ctgttggtat atgcttaaag
    52861 gcagtaagac aatatggaat ggcattaaaa tttgtaaaag aacaaacaga agaaatttgt
    52921 acagaagcta taaaacaaga taaaagagca cttagttttg taaaaggaga taaggaaaaa
    52981 tacaaggctc tatatgataa taatgaacca tttgcaaaga gatatgttag aaatgtaata
    53041 gaaaaagaaa acagagcatt gattaaaaaa ggagaagaaa atgcaaaaat caaaattgca
    53101 ggaaaacttt atgatagagg catgtctttt gaagatatat cagatatagt tgagattgaa
    53161 ataagcaagt taaaagtgag tttaggtgtt ttttaaagta ataaatgtag gtgtttttta
    53221 tgggaaatag ttaataaaaa aataatcgac tagctctttg taggacagca aaattagtga
    53281 tataatttga tgtataataa attattttta ttagataagg gggaattaaa gttgaagatt
    53341 acagtattat accaaacaag aagtggaaac acagaaaggg tcgctaagct gatagaagat
    53401 ggagctaaaa aggtggatgg agtagatgta aagcttatga gacttgataa tattgattta
    53461 gattatttaa atgaaagtaa agcagtaata tttggaacac ctacttattt agcaaataca
    53521 acttgggaag taaaaaaatg gtttgatgaa gattcaaaaa aagttaattt agctggaaaa
    53581 ttaggagctg tttttgctac atgtgattat atatgtggag gtccagatgt tgcgatactt
    53641 actatagtag gacatttgat ggttaaaggg atgcttgtgt attctggagg tggttcttta
    53701 ggaaagccat ttatacattt aggacatgta cattcaattg aaggtccaga gttacaagat
    53761 gagaaggcta taatatttgg tgaaagaatt gctactaagg caaaagaact atttgcttaa
    53821 tttctatatg cataataatg attagagtaa atttagggtt ttaatggaga tttgaagtaa
    53881 aagttataaa ataaaaaatt ttccataaaa ttactcaaga tgaattataa tataattata
    53941 aataaattat attattaaaa tatttaaaat caaacgtcaa tagcgaggga agtttatggt
    54001 atggcatata gaatatgaga ttttttctgc aattatagtt atttttttaa tggtatactt
    54061 ttttagaagt aaatttatac ctactttaca aaacaaaata tattgtgcac ttttaatatt
    54121 ctcattttta tttatacttt caaatatttt aggttcattt tgtctaaata atatagacaa
    54181 aattccaatt tttattactt ttttattgaa tcagatatac ttattgttat tgccaatacc
    54241 agcagctctt gtatcatttt atgttatggc tattatttat caagatataa ggtatatgaa
    54301 aaaaagatta ttatttttat ctataccact tataatttgt ataatcttat ctattacaaa
    54361 tccttttacg catattctat ttggattgtc aaaagaaaca ggttatatac ggggttgtgg
    54421 atatgttgca acttttgcat cttttttctt ttatgcaata tattcagcat ttttatcttt
    54481 taaatataga aaagcaatgc atgaatcaaa aatatgggct attagaggtt ttcttatagt
    54541 ttcaattgtg gcaattatct tacaggcaat ttttttacag tatcttctta caggaactgc
    54601 atgtgcatgt agtttacttt tgacatatct ttctatgcag aatcgaggtc ttattattga
    54661 tgaccttact ggtgtactca atagacaatc ttttattcaa gagctagatt tgaatatcaa
    54721 tactgaacaa tcaggattta ttattacaat tgcgcttgat gattttaagt ttatgaatga
    54781 aacttttgga acaaaaaatg gagatattgc actaaaagaa gttggaaaat atttgattca
    54841 gatacatgat gtaaaccatg tatatagaat agggggagat atattttcta ttgttgtcaa
    54901 tagtcaatta ggtatagaac cagatgatat tatcagaaag atagaagaaa gatttaaaaa
    54961 gccttggcta gtagaagaga taagttttaa tttagcaact agtattgctg ttgtttatta
    55021 cccagaaaat gcagaaacga cagaagatgt aattgttgct atagatttct ctatacatga
    55081 agcaaaacgt tctgagtcaa ggcgagttgt ttatgcagat gcgtctataa gtgaaaagat
    55141 aaagaagaaa catgttatta aaaattgttt aaaagaagca ttaaaaaatg atgggtttga
    55201 agtgtactac caacctatat tttctaatag caggggcagg tttacttcag cagaggcatt
    55261 acttaggcta gaacacaaag agttaggttt tatacctcct gatgaattta ttccaattgc
    55321 agaacaaaca ggattgatta actcaattgg attagtagtc tttgagaagg tatgtagatt
    55381 tatagctagt gatgagtttg aaaatttaaa attggataat atagctgtga atctttctgt
    55441 agtacaatgt atgcaaaaaa acttagctga tgatttactt tatcttatga ataaatataa
    55501 tgtatcacca actaaattta aacttgaaat tactgagact gtggctatgg gctcttttaa
    55561 tataattaaa gaaacaatgg aaagattaat tgatttaggt gttaagtttg cacttgatga
    55621 ttttggaatt gcttattctg gagttactaa tatgctttct ttaccatttt cagtaattaa
    55681 gttagataag agtttgattt ggtctatgaa tgaagatagt aggcataagc ttacagttga
    55741 gacgattata gctcttataa ataaattgaa tatgaaggct gtagcagaag gtgttgaaac
    55801 cattaagtgt gctgaagatt taatagctat ggagtgtgaa tatttgcaag ggtattattt
    55861 ttctaaacca gttccagaag atgtttttaa aaatttgttg aaagaaaata cttttacaag
    55921 ttaacaccct ttattttttt aattacaact ttgttcattg acactgccag cgatatatta
    55981 taaaattaac acaataataa atattaaatt tattatacat attattaata ttaattaatg
    56041 gagtaaagat ttattatatt ttatttaatt atcctaaagt gagaaaggaa gatgtgacat
    56101 gaataaaaag aaaatattag tgccaattga tgggacagaa agaagtatgc attctttgga
    56161 atttataaaa ggaatattta aaaaagatga agttgaagta gaaataatga atgtaaaaga
    56221 actagtattt attgatggca tatccctggc tgaagagata aaaaattctg aaaatttagg
    56281 aagaagaatc ttggataaag cagcagagat aatgggagag tatgatgtta aagtacattt
    56341 tacttttgga tatccaggag atgagataat tagaaaagca aaagaagata atgtagattt
    56401 tatagttatg acaaaatcta ctaaaaaagg tcttacaaga atgataggtt cagtaacagc
    56461 aagtgtagtt aaacaagcaa aatgtatagt gatgattgta ccggagtaga attagaaagg
    56521 tatttgaaat atgaataaaa agatagtagc agtttgtgaa agtgaaagaa gtttaaattc
    56581 tcttaagaca gctgcaaatg atttaggatt tgatttagtt tatgaaattc aagaaaatga
    56641 taatataaaa aatgaacttt ctatttatga tatagaagat gcatctatag tgttatttgt
    56701 tacaagtgat tctatagaaa gcatagagaa gattgataga tttatagata gagaatttta
    56761 tgaagttgat ccaaagtata taatagagga tgcaaaatct atagtaagtg aaattttaat
    56821 agacttaaat taatcgtggg tgtcgcacta agaatagagc gacgcctttt tacatatttt
    56881 acataagaaa taaagggctg tctcaaacta tagataagac tctttttcat tgttgaaatg
    56941 atgaaaatat atttgatttc atacaaaaaa gagtgcctca taactaaaaa gttcactttg
    57001 agacactcca tttttatatg ttagttgcat ttaaggtaaa atagaagttt aatcatgttg
    57061 aaataactga attacatctt ctaaatgatt gtacattgat gtataaccta agtaagagtc
    57121 tttactatca aatgccatca ttatcttgtt atggtggcta atcatatcct taagagaatt
    57181 tctatattta aaaccgaagt attggttaga agaaactgtt ttaggtatta actcataata
    57241 ttttataaaa attggattat gagaagctaa aattatctct ttgtgaaatt gtaagtcagc
    57301 atcataacat tcttctatca aaccatgaga aaccttatcc aattcctcta ttgactttag
    57361 gtaagtatat tttatttttt gaagttcttt agatgtagca tttaaaattg ctagtttagt
    57421 agcttcactt tcgataagtt gtcttgctct taaagattct acataaaatt cttgtatgtt
    57481 atgattttta tagatttcac catcatcaaa taggtcaact tttttaaatc cttcaactat
    57541 aggacttgag taaggcacag ctctaagtat tccttcctta cagagtatat ttatggcatt
    57601 tcttacaggt attctactta tgttaaatag gtcagcaatc tttctctcac ttggtaattt
    57661 actattaatt ttaaaagttc catttagaat gtttaattta atataatcaa taattttttc
    57721 agtggcattt aagcttttca taaaaactcc taaacatata atttttttat gattgtatta
    57781 tatcatagtt aagagttaaa tctacttttt tataatatgt ataagacagg atagaggcca
    57841 aaatagctat aatagccaag ataaagtatc catattgtat tgaagtatat tccgatattt
    57901 taccaactat cattggaaat acagacattc ctatagcata aattgcttga aaaaaaccca
    57961 ttgcagtaga tttctgatgt tttggtacat ttttcataga ctcgctagta aggtaagaaa
    58021 ggagtatacc tgtagatata cctggtagca cttgtagtac aaatattata ttaatatttt
    58081 ttattgttgg aactaaaaag caataggctg aaactaaaat aaaaactaaa ggaatccaaa
    58141 attttggccc atacttagta caaaatttag tagaagcaaa gccagaagaa gcaacagcac
    58201 acaccatgta agatatagaa gatagaccta tgagggtaga actagaacct aagtttttaa
    58261 gaatttgagt agtaaatgac attgttgtag acatttgaat accctgttga attaatgcca
    58321 taaaggaaaa aaatacaagt cttttatctt tgcagataga taaatatttt ttaattgata
    58381 ttttttcagg tatttttttt gaattatgat tttttatatt taaggctaga atcgttccaa
    58441 taactgaaga caatacactc atgatacata aggctgtcat tcctaatttt tcataaaata
    58501 aagtactcat aacaaatcca atcaacattc ctagattgtt taccaatatt atcgtactcg
    58561 tagctttttg ttgatgttct gtagaaaaaa agttggtata gtgaaccatg taagaaatcc
    58621 aagttgatga tgatattcca gataaaatgt tagctataag aaaaccattg cctccaggag
    58681 aaaagactct tataagagat gctaaaccag caaagaaaat tccagacagt ataaatattt
    58741 tatgtttatt tatagaatca gcaaatactc caacaggaat ccttaataaa cattgtgaga
    58801 ttccatatgc acctattatt ataccaatca tatttgtaga tacattacat gcacttaaat
    58861 atggattttg gaaaggtata tatacatatt gtgaaaacca gaaaaatgta acaatagaaa
    58921 gtaaaagtaa tttttgatta gatatttttt tcatattatc ctccatatgg tatttttata
    58981 atgcaaataa tataccattt agatttttta atcaagtact ttctctatta aaaaaaattt
    59041 aaatatataa ttattattta caaaaaaatt atactttata gttgaattaa gaaaacgctt
    59101 atgatactat aaagttaaca aatttgaata tataacagta gacgtgttac tggtaatgca
    59161 ggcaagatcg aatcaatttt tatagattat ctatagagta ctatgggtat aatctattta
    59221 tttggttcga tttttttgtt taattggcca taaaacaaaa agcctatagt tgaaaatgga
    59281 ggatttttta tggattataa aaatatagct caagaaattc tactaaatgt aggaggaaaa
    59341 gagaatgtaa atgaagtgac tcattgtatg acaagactta gatttaaagt caaaagcgct
    59401 tctaaagtga ataaggataa attatctaaa actgaaggag taataactgt tgttgagagt
    59461 atgggtcaaa tacaagttgt aattggaaat aaagtaaaaa cagtatatga tgaggttata
    59521 aaaattgtac ctcaatcaaa tgacgtaggt aaaaagaatg aaagtcaaga aaagcaaagt
    59581 ataattaatt ctatattatc agcagtagct ggtatattta cacctacaat acctgctata
    59641 gcaggggttg gtatgattaa aggtatttta tcagttcttg ctatgtatta tatgaataaa
    59701 aatggagtag atataaaaga aacgcaaagt tatattatct taaatgccat ggccgattct
    59761 atattctatt ttatgcctat tatactagga tatactgcgg ctaaagtatt taatgcaaat
    59821 aaaataatat ctatggtatt aggagctaca ctttgttatc caacttttac tgctttgatg
    59881 gcaggtgaag aatctgttag atttttagga ttggcagtaa caaaagctac gtatacatca
    59941 tctgttattc caataattat tgctatatgg gctctttcat acgttgaaaa agtattagaa
    60001 aagtatatac ctgaggtaat taaaataata atggttccaa ctttatcatt ggttgtaatg
    60061 ttacctgcaa cattattttt atttggacca atcggaattt atataggaaa tgtcataaac
    60121 ttttcttata agtatattta tgaattaagc ccagcgttgt gtggagcatt tgtaggtggg
    60181 ttatggtgtg tgttggttat atttggtgct catagagcat tattaccaat aggtataagt
    60241 gatgttgctc aaacaggaag acagaattta ttggcatttg caggagctgc aaacttttca
    60301 caagcagggg ctgctctagg agtattcttt aaaactaaaa atcaaggact aaaaacaatt
    60361 tctatgtctg caactataac agctttattt ggtataactg aacctgcaat atacggtgcc
    60421 aatcttagat taaaaaaacc tatggtatgt gccgtaatat gtggtgcatt tggaggtgcg
    60481 ataatgggaa tgggtggagc ttatggtaat gcatttgcaa accaaggtgt tttaactata
    60541 cctgtatatg ctgaagcagg tgcattaggt ttcttaagtt atctaggtgg ttgtgctata
    60601 gcattttttg gttcagctat ttcaacttat ctagttggat ttgaagattt ggaagagtct
    60661 tctaataagg aaaattcatt tataaaagta gaaacgaagg atggtgttat tgatataact
    60721 tcacctgtag agggcgaatg tatagaattg tcagaagtaa aggatgatgt atttgcttca
    60781 aaagctatgg gagaaggtat agctgtgtta cctacaaaag gagtaataac agcccctact
    60841 gattgtgaag tagcttcttt atttccaaca ttacatgcaa taggattaaa attagataat
    60901 ggagcagaaa tgttaataca tgttggaatc aatacagtag agttaaatgg taaatacttt
    60961 acaaaacatg ttaatcaagg agatttagtg aaaaaaggtg ataaacttat atcgtttgat
    61021 atagataaaa taaaaaaggc tggttatgat gtaactacgc cagttatagt aaacaataca
    61081 tttgattttg ggcaagtagt ttcttgtaaa tctagttatg tttcaaccaa tgataatata
    61141 atttcattag tattagctgg taattaagtt aatttgacta gagataagta aattgattta
    61201 aaaggaaata agtaaatcaa caattaaata catctaaaag taagtttatt gcaatgaatt
    61261 gttaaagaaa ataattaata tggagtaaag ctattgcaat gaagtaacaa agaaaataat
    61321 taatatagag taagtttatt gtaatgaatt gttaaagaaa ataattaata tagggtaaat
    61381 ctatctcaat gaaataacaa agaaaagagt taatatagag tgaacttatt gcaatgaatc
    61441 aacaaaaaaa ataatcaata taaaaaggag aaatatttat gaatacagga tttccaaaag
    61501 actttttatg gggagcatca tcttctgcat ttcaagtgga aggagcttgg gataaagaca
    61561 ataaaggaaa aaccgtagcc gactataatt cttttaaaaa gtctcattta caggcagata
    61621 ctaaagttgc atcagacttt taccataatt atgaagaaga tattgaatta atgaaagaat
    61681 tagggatgaa aacatatcgt ttttcaattt catgggcaag gataatacca gatggtgaag
    61741 gagagataaa ccagaaaggt ttagactttt ataataagat aatagacaaa ctaatagagt
    61801 gtgatattga gccattcgta actttatacc attttgacct tccatttaaa ttagtagaga
    61861 aatataatgg ttgggaaagt agagaaactg tctatgcttt tgaaagattt gctaaaatat
    61921 gctttaagca ttttggagat agggtaaagt attggcaacc tcataatgaa cagaatttaa
    61981 ttgttagagt ggaggagaga attaatatat atgatgaaac agattcatgg aagatagata
    62041 aaatgcgtgc tcagatggat tataatcttt gcttagcaca tgcattagca gtcaatgcat
    62101 gtcatgagat gataaaagaa agtaaaattg gagcagcagt atcatcatct gtaacatatc
    62161 ctcttacttc taagccagaa gatgtatatg cagctagaat gaatgataat tttaaagtgt
    62221 actatatgct tgatatgcat cattatggag aatatccagg gtattatatg aagtatcttg
    62281 aaaaaagaaa tacagttcct cacatggaag atggggataa agagatactt aaaaaagcta
    62341 aaatggattt tatagctgta aattattata ggacaaattg tgcagaagct ttacctgaag
    62401 attcacaaca tccatttgga ttaagagaag gaactgttga ttttagtatg tatggactat
    62461 ttaaaatgtc aatgaatcct aacttagagg cttctgagta tggagcagca atagacccat
    62521 caggtcttag agttgcctta aatgaatatt ggcaaagata tcacttacct gttataataa
    62581 cagaaaatgg tctaggagct aaagatatat tagaagatgg aaaaattcat gatgactatc
    62641 gtatagacta tttaagaagt catataaatg catgtaaact agctattgaa gatggtgtag
    62701 agatgattgg atattgtcca tggtcattta cagacctttt aagttcttct caaggtttta
    62761 ataagcgtta tggacttgtt tatataaata gaactgacca tgaagtttta gatttaaaaa
    62821 gaatcaagaa agatagtttt tactggtata aagaagttat agagaacaat ggaatagtaa
    62881 aataaacata aatatatatt gagggtttta gtatgtacat tacaaaggta ttaaataatt
    62941 cgttgctact tgcaaaggat gataatgatg aagaaataat attgatgggg aaaggcattg
    63001 gccataatta taaggccggg tctgagttaa ataaaaaaga tatagaaaag atttttgttc
    63061 ttcatgatga aaatataaaa aagagtatta tacaattggc aacagaaata gatgcagaat
    63121 attttggtat agctcaaatg ataattgcat atggaataga aaaatataac ttaaaactta
    63181 tgaaccatat atatttggcc ttaactgacc acattgcctt tgcagtgaga cgctttaaag
    63241 aaggtataat gattgaaaat cactatttgt tcgaaatcaa ggaatttaat ccaaaagagt
    63301 atgatatagg aaaatatgct attactgttt ttaaggaggt tcttggttta gacctaccag
    63361 aagaagagat tggtaatata gcaggccatt ttataaatgc acaacaagat aatccttata
    63421 gtgatagaaa taagagaagt gctaaaattg taaatgctat tttgcaaata gttcattatc
    63481 acttttctat tgtatataat aaagagtcat tttattatag gagatttgta atgcatctaa
    63541 aggccttttc acaaagattt ctggctaatg aaccatcaag agaaaaaata gattttatat
    63601 atgagcaagt tcaaaaaaat tgtaaggaag agtatgaatg tgtgaaaaag gtaggagctt
    63661 atatgtataa ggaatactcc agagaattac caagacaaga ggagttatat ttgatgattc
    63721 atattcataa gattttagga gaattatgcg aaaatagtta gaatatctta atatgctagt
    63781 aatattataa aaaattaaaa attaactaca ctttaaatat gaacaattgc attacttaag
    63841 ggggttgtct taaaattgat ttttttaatt aaatttgaag ctcaactcct tttttaaacc
    63901 tttatatcat tacaacttta atgtttatac gcctgtactt tagatgtata tctacttttt
    63961 acatttctca acatgcaaac ctaccatttt ttgcagtatg ttaattgaaa taaaccattg
    64021 agttaaccct aaatttattc tggacttata ggaatagttc caaagatact ttaaaatatt
    64081 ttctggaata attgcttatt tcacatatgt tttattgtga tgttttgatt taataaattc
    64141 ttcaactctg tatatagtaa atgtattatc atgtttgttt tattcaagca cacttataat
    64201 acgcttgatt ttttcacaat gatgaaatat actaatgggt gttataggta taagaatcga
    64261 attacacttg aagaagtaag tgataaatga gatataaatc ctcatatgat aaactactat
    64321 ttcattgagg aacatattct aagtgatgtc aagatactac aatatgacta aattcctagt
    64381 gataaaaaag tctacgaatg agtgtagaaa ggggaactaa gatgaataaa gttttaatta
    64441 tagatgatga taaagatctt tgtattttgt taaaaaagag tatttcaatt gaacagattg
    64501 aagcaaacta ttgccattct gggagagatg gactggttga actttcaaaa caagattatc
    64561 agttagtagt tctagacgtg atgatgccag gtatggatgg ttttgaaact atggaacaaa
    64621 tacgaaaata tagcagtatt cccatcttaa tgctgacatc aaaaagcgat aattacagca
    64681 aagtgcatgg attgcgagct ggtgcagatg actatctaac caaaccattt gaaattacag
    64741 aatttactgc tcgtgtactg tctttaatcc gacgttacac ccgttttaat ccaaaaaatg
    64801 aggaaccaca gcaactttct ttcaaaggtt tgttgattga ccttgaccag catacagtga
    64861 ctaccaatgg cgaacctatg ttgcttccac ccaaggaatt tggtgtgctt ctttactgtg
    64921 caaggcatca gggtaagatt ttgacaaaac agcagattta tgaagctgtg tggggtgagc
    64981 catatgtata tgatgacagc aatatcatgg ctattatcag tcgcctaaga aaaaaaattg
    65041 aactagaccc atcatctccc atctatttgc aaacaataaa aggaattggg tatcaattca
    65101 acacggaggt atgaaaatgg atgaacaaac gataattctt ttcttattct tgctgtcgat
    65161 tggtctactt tttctttcca tatttgcttt ttccaagctt gggcatattc acaaacgcct
    65221 aaaagatata gaggagatac tggctgatgt acaaattgga aacgaaaatc gcaaaatact
    65281 aattaagcca tgtgatgtta tggctccatt ggtttatcag cttaatgaga ttgtctacga
    65341 ttatgaaaat aagttacttt ctctgaaaaa gtcggataaa gctagcaaac aacttatgac
    65401 aagtctatct catgatgttc gtacaccatt aacaactctg attggttatc tggatgctgt
    65461 acacagtggt atagttatcg gacaagaacg ggaggaatac cttgaaatcg ctaggcgtag
    65521 agcctacgac ctcaaggatt acattgatgt tctttttgac tggtttcggt tgaactctga
    65581 tgaatttacg ctgtcaatag aatctgtgga aattgcagag ttgtcacgca atattttgaa
    65641 agactggatt cctatattcc atgaaaagaa actgaatttt gaaattgata ttccagaaaa
    65701 tcgactaatg gtaaatctcg acccagatgg atattcccgt gtggttaata atctggttca
    65761 aaatgttctt gctcacagta aggctcggca aatcaagatt accatgagtg aggattccag
    65821 aatggtatta ctccgtgttg atgatgatgg tgttgggatt gccagagaaa atttaccaca
    65881 tatttttgag cgactgtata agtgtgataa aggacgttca gaaaaaggaa gtggtcttgg
    65941 tctatctatt gtcagtcaaa tggtggagcg aatgggtggt cagatttccg tagaaagtga
    66001 gattggaaag tataccgtat ttacagtgag cttaccatta atataaaatt gtttttcccc
    66061 catgtgacat gtatacacag ggggattttt tgtaagttat aaagttgcaa ggttaataca
    66121 aggttgttgc aaggttaatg taagattgag gtggtatgat agctttaata aacaaaggag
    66181 gattttatta tttatgaata atttaattat tgaaacaaaa aatctcacta agcaatatgg
    66241 tgctcaaaag agcgtttcta atttgaatat tcacgttcag aaaggtcgca tttacggatt
    66301 gctaggaaga aacggtgcgg gtaagacgac aactatgaaa atgttattgg gtctaacaaa
    66361 accaactact ggagaaatta aaatatttgg tcaggacatt cacaataacg agaagaagct
    66421 tcttcctcga attggatgtt tgattgaatc accagggttt tatcctaatc tgacaggaac
    66481 agaaaatctc aaaatctttg caaggcttag aggaatacca aaaaaaaatg cagtagaatc
    66541 agcactggat gtagtcggtt tgccaaacaa tgacaaaaag ttattttctc aatactctct
    66601 tggtatgaaa cagaggttgg cgattgctct tgccattatg catgacccac aactgttgat
    66661 tttggacgag cctatcaatg gacttgatcc tattggtatt gcagaagtaa gaaagtttat
    66721 tcgtgatctc tgcacagaac gaggtaaaac tattttgatt tccagtcaca ttctttctga
    66781 aattgccttg ttggcagatg acattggtat tattgaccat ggtattttgt tggaggaaga
    66841 aagtcttgcc caattagaag aaaaaaacag taaatacata cattttgctg tatctgatgc
    66901 agcacatgca gcaaggcttc tggaaaccca acttaacctg aaaaatttca aagtagcaga
    66961 taattacaat attatgctat atgatacaga tgtttctgtt gcagaaataa atcgtgcttt
    67021 cattctaaac aacattgagg tatcagaatc tcatttatgc gaagatactc ttgaagatta
    67081 cttcaagaaa gtaacagggg gtgaaggaat tgcttgatat aatttcatgt gaattttcaa
    67141 aactcaagcg gttaaaattt atactgattt ctattttagg tgcttgctta tttccaattc
    67201 ccgcaacaat tttgattgca aaggacaact tgccctttga gcaattgttc aaattagttg
    67261 tcaattttgg atattttttg ctattaccaa ttgtattaag tattgttgct agccaactat
    67321 tttttataga aagagataac gatgtattaa aaaatcttgc aacagtgcca gtgccaaaag
    67381 gaaaactggc tctggcaaaa ttggctgtgt tgctgtttat atcattgttc tactccgttg
    67441 cagggttagg agctactatc attggaggtt tcattgttgg aatagtagag ggggttactg
    67501 taaaattagg aatgagcatt gcttttggaa ttatgttttt tgttactgta cttcctgttg
    67561 tggtactcat tgtatatttc aatcgcagct atattttttc tattatactt tcttttgtat
    67621 atgctatttt caattttagt atatccttaa atattatcaa ttttgaacca aataacccac
    67681 tattaagcgt attacctgct cctgttataa tgcgttggtg gatggcattt tggggagatc
    67741 ccactggcga atacacggca cttagacagc catatttgct ctcaactcct gcttgtgtag
    67801 gtattttatg tttgataacc attatagcag tcctgctgat ttgtatgata tacaaaaagc
    67861 aggagaatta ggaggtatct atgcttgata taattactac agaatttcaa aaaataaaaa
    67921 gatataatat tctatggatt ggtgttgttg ctgttctgtt ttcagcacta ttggcagttt
    67981 ttcaggttgt aagttcacac ggcagtgacc ctctaacgta tgagagcttt gcaaacggag
    68041 ttatctggaa taatttcagt cttagttttc catttgggat tacacttatt ggaggatatc
    68101 ttattaaccg tgaatataca gaccaaacct taaaaaacat cctaactgtt cctatttcat
    68161 tacgcaaatt gctagtggga aaattaattg cggttggagg aattgctgta ttgttaagtc
    68221 ttttcagctt cttatgcaca tttattttgg ggttgttatt ttgcaatatc aatatatctg
    68281 ttacactcat tgtaaaatcc ttagttcaga ttttgtctgt taatctgtat tgttatgttg
    68341 ctgttttgcc gattattgct tattttggtc gtaaacaaaa tgcatttctg acgggtgtag
    68401 ggattgcatt tgtatacggg ttttgtggtg tgtttgttgc tggaagaaat ctgacagact
    68461 tttatccaat cacagcaggt cttggtctag ttggatacaa caatggtgct ggtactgttt
    68521 atcagccact tatcggtgct atgactttga ttgtaattct aatcttgaca actattctac
    68581 ttgtatttac acctaattat gataaagtta tgaccatatc taagaaaaaa gggataaagc
    68641 ataaaaagta ttctcataaa taacataaat attgtttcta ttatttaagt tgctagacag
    68701 tgaaaagaaa aaatctgtcg tacagtggct atatgctcat gtattcaaga agctacagtt
    68761 ttgatttttc ataactgtag cttctttttg tatttattaa atcacggcta tcataatact
    68821 tgcaataggt atagcgacaa gagagagtac tgtcatgtgt gttttatata ttacattaag
    68881 tatattctaa aatatatgtt ttaaataata tatttgaaaa taggaatatt taaataaaaa
    68941 aaataatatt atatatagtt gacaaaaatt ggcaaatgat ataatatata aatatagaaa
    69001 tagtaatcat tactattatt aaaaagggag gaattaatta tgaacttaaa aggaactaaa
    69061 acagaaaaga atttaatggc aggatttgca ggagagtcag aagcaagaaa taaatataca
    69121 tactacgctt caaaagcaag aaaagaaggt tataatcaaa tagctgctat atttgaagaa
    69181 actgctaaca atgaaaagga acatgctaaa ttatggttta aacttttaca tgatggtatg
    69241 ccttcaacag aggaaaattt aaaggatgca gcagcaggtg aaaactatga atggactgat
    69301 atgtatgcaa aatttgctaa agaagctaga gaagaaggat ttgacaagat agcttattta
    69361 tttgaagctg ttggaaaaat agagaaagag catgaagaaa gatacttaaa gcttttagaa
    69421 aacttaaatg aaggaaaaat atttaaaaga gatgaagaag ttgtttggca atgtcaaaac
    69481 tgtggtcatg tgtatgtagg tactgaagca ccagaaaaat gcccagtatg tgaccatcca
    69541 aaagcgtatt tcaatataaa agctgaaaat tattaaaaat tatcattatt aaaaaggaat
    69601 gttaactatg aaattttcta aacaacgaga actgatttta aatgaaatat taaataatcc
    69661 ggttcatcct actgcggatt acctatatga aaacttaaaa aaagataatc caaatttaag
    69721 cttaggaact gtttatagaa atttagctca gctaacggaa catggcttta taagaaaggt
    69781 tagtattcca gggtatccag atagatttga tggtcgaata gataatcact atcatatcat
    69841 atgtgaagta tgtggagagg tatacgattt agaatccgaa gttcttaata atttacaaga
    69901 attaatatct gaggagacag acataaaaat aacatcttat aacataagtt ttaaagggat
    69961 ttgtaataat tgtaaaaggt gtagccaagt aggttagttt tcaaattcta aaaataatta
    70021 atgaggtgag tttatgtgta gtgaacaaaa attttttata tgtgagactt gtggaaacct
    70081 tgtaggaatg atacaaagtg gtggtgtacc tattttctgt tgtggaaaac ctatgaagga
    70141 acttgttcct aatacaacag atgcagcagt tgaaaaacat gtacctgtaa ttgaagtgga
    70201 tggaaataat gttactgtta aagtaagtag cacaactcat ccaatgacta aagaacatca
    70261 tatagcatgg gtgtatctta tgactgaaca aggtagtcaa cgcaaatgtc tagcagtaga
    70321 tggagaacct gtagttaaat ttgctttgaa tgatgatgat aaagtgattt ctgcctatgc
    70381 ttactgtaat ttacatggat tatggaaggc tgaactgtaa tatttaaata aattgagtca
    70441 aagaggaggc tataaatgta ttttcataca aatagcctcc tataaattta tataaattca
    70501 agttttaatt ttgtttaatg tcaatataat ataaggagaa aataatatgt caatttataa
    70561 atgtagtgtt tgtggatata tttatgatga atctaagaat gataaaacat gggatgaatt
    70621 aagtgaagat tgggaatgcc ctgtatgtac aaaaggtcgt agttattttg gaaagataag
    70681 cactgtttac tatgaagaag atgaaaagat agcagaagac atagttgaaa atgaatctaa
    70741 attaaatact gaaaaagagg gagatttaaa ttacttaagt acatatttaa gaagagatga
    70801 tgaagttgag aaacatatgg atataattca cgaaatggct gttacaggaa aatctataat
    70861 agaacctatg agaactaaac taccagtaat ttcttgggat gatattttaa ttatgggtgc
    70921 tcaattaaat ccattacctt taaatgagca tgatgaagta aatacaacaa caataatagg
    70981 aaaaaaagca aagaaaccta tgattataga aaatccagtt tatatttccc acatgtcatt
    71041 tggagctttg tctaaagaac taaaaatagc tttagcaaag ggtgcagccc aaaataagac
    71101 agctatgtgt agtggtgaag gaggtatatt accagaagag aaggaagctt catacaagta
    71161 tatttttgag tatgtaccaa ataaatatag tgtaactgaa gaaaatctta aaaattctga
    71221 tgctatagag ataaaaattg gtcaaggaac aaaacctggt atgggaggtc atcttcctgg
    71281 cgaaaaagta actgaagaaa tagcaaaagt aagaaataag cctgtaggtc aagatgtaat
    71341 aagtccatct tgttttgagg aaatacaatc caaagaggat ttaaagaaac ttatagatga
    71401 acttagagaa gtttcagaag ggcgtccaat aggtgttaaa atttcagcag gtcatattga
    71461 aaaagatatg gaatttatag cttatgctaa acctgatttt gtaactattg atggtcgtgg
    71521 tggagctact ggagcaagtc caaagttgct taaagatgca acttcaattc caacaatatt
    71581 tgctctttat cgtgctagaa aatacataga tacacatgga ttagatatag atttggttat
    71641 aacaggtggg cttcgtatat ctactgattt tgctaaggca attgctatgg gggctgatgc
    71701 agttgctatt gcaagttctg ctcttatggc agcggcgtgt caacaatatc gtatatgtgg
    71761 ttctggtaag tgtcctgtag gagtagctac tcaggatgag gaattgagaa aaagattaca
    71821 tatagaaaat agtgctaata gagtggcaaa ctttttaaat gtaagtttag aagaacttaa
    71881 gacttttgct agaatttctg gtcataaaga tatacatgat ttaagtgttg atgatttata
    71941 tactgttaac tctgaaatat caaattatac aaacatacag catgtataga ttgaagtttg
    72001 aaactattag attttagata gctataaaag taaatgataa atatatttta taaaagagag
    72061 tgtcttaaaa tgaacttttt agttcataag tcactctttt ttgtatgaag ccaaatatat
    72121 ttatcatttt agcaatgaaa aagaatctta tctctttatt ttgagataga ctccttctat
    72181 ttatgaaaat taaagatatt aaattgtaaa atattctgtg atgtcgtact attaaactaa
    72241 agattctgta ctttaaagta aataaaaatt taaggagtgc ttattatgga aagattgaag
    72301 atacaagttt tagttgacaa taatacttat attgatagat actttgttgg agaaccagca
    72361 gtaagctatt atattgagat tgatggaaat aggattttgt ttgattcggg atattcagat
    72421 gtattcatat caaacgctga aaaattaaat atagatttag gaaatttaac tcatgttgtt
    72481 ttttctcatg gacataatga ccatacaaga ggtatccagt ttttagaaaa taggtatgat
    72541 ttatctacag ttgaacttat ttcacatcct aactgtttta tacctagaaa acatggagag
    72601 aaaagcatag gagctccatt ttctgctgag gaaattaaaa atatttttat gtataatcct
    72661 aaggataagc catttaatct aagtaagaat tgtgtgtttt taggtgaaat accttctata
    72721 aataattttg aaaaaagagc taaaattggt aaatgtaaaa taggagattt gtgggaagat
    72781 gattatgttt tagatgattc tgctatagtt tgtaaaactg ataaaggtat ttttattgtt
    72841 acaggatgtt ctcatagtgg aatttgtaat atagtagagt atgctaaaag ggtatgtgga
    72901 gatgatagag ttattggtat actaggtggt tttcatcttt ttgaattgaa taataggtta
    72961 gatagtacaa tacaatattt ggataaagaa gaaataagaa tgttgtaccc ttgtcactgt
    73021 gtttctttta aggtaaaagc taagatgaat gaaatattga atataaatga agttggagta
    73081 gggctgacca taagtatata gtatttgaaa gtatataaga tttaagttga aggttaaaaa
    73141 gatattttct atataaagta tcttttttgt tacgtttatt ttaagagaaa tc
//
LOCUS       DAMJYN010000007        72239 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.007, whole genome shotgun sequence.
ACCESSION   DAMJYN010000007 DAMJYN010000000
VERSION     DAMJYN010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 72239)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 72239)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..72239
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.007"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(121..894)
                     /locus_tag="PC466_000552"
     CDS             complement(121..894)
                     /locus_tag="PC466_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SigB/SigF/SigG family RNA polymerase sigma
                     factor"
                     /protein_id="HDF2767979.1"
                     /translation="MKNVANATHYLNMDTKELFNLYNKNKNVDIRNILIERHLYLARL
                     LAKKYINKGVDFEDIYQVASLALIYAIDRYDVEKGFEFSSFATPTIVGEIKKYFRDKV
                     WTLRVPRRIQELSKKISDAKIKLEQENKKHPKVKDIADYIGVSEEDVLEAMEASYGYQ
                     PMSLDSSSNDDSEDKDITLIDKIGKEEGNFGSIEYEDFINKFIETLNELEVKIFKDRF
                     FFDKTQSSIAKELGISQMTVSRLEKKVVEKLKKEYEKNL"
     gene            complement(894..1280)
                     /locus_tag="PC466_000553"
     CDS             complement(894..1280)
                     /locus_tag="PC466_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF2767980.1"
                     /translation="MEITTNPDYVSIIRLTASGIANKMGFPIDDIEDIKVAVSEACTN
                     AIKHSKDDVFNIVFNILDNAINIEIQDNGKGYDVSSISTPDLENPKESGLGLFIIKTL
                     MDDVDIESEHNQGTKIKMTKYLGVDI"
     gene            complement(1305..1622)
                     /locus_tag="PC466_000554"
     CDS             complement(1305..1622)
                     /locus_tag="PC466_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="STAS domain-containing protein"
                     /protein_id="HDF2767981.1"
                     /translation="MSMNIDSNLDSQNKFWNVCLDGELDVSTADKLKEHLHALIEKNM
                     LDVKINLKDLDYIDSTGLGAMIGVLKKLKINEKEIYIVNPKSNVKKIFTITGLDKIFK
                     VEG"
     gene            complement(1634..1894)
                     /locus_tag="PC466_000555"
     CDS             complement(1634..1894)
                     /locus_tag="PC466_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HDF2767982.1"
                     /translation="MNAWGWQIGAVLVGSSALIVAIYLAKTLNSINKVVEKAYKIVDY
                     NERHIQDIVENASSISKGIDDIVYVINKILSIGNIFKIIKRK"
     gene            complement(1894..2190)
                     /locus_tag="PC466_000556"
     CDS             complement(1894..2190)
                     /locus_tag="PC466_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HDF2767983.1"
                     /translation="MCNKRSCKKGGFLLLGAILGFIFGMFFAPKKGSELRKETKEKFN
                     DVKENPKEVLHETFNDVKERIINLVDDDNNEEDIKISEEDIVISKSFDDEGDVN"
     gene            complement(2259..4685)
                     /gene="gyrA"
                     /locus_tag="PC466_000557"
     CDS             complement(2259..4685)
                     /gene="gyrA"
                     /locus_tag="PC466_000557"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HDF2767984.1"
                     /translation="MEENNKILPIEIAEEMKKSYIDYSMSVIAGRALPDVRDGLKPVH
                     RRILYSMSELNLTPDKPYRKSARIVGDVLGKYHPHGDIAVYYAMVRMAQDFSTRALLV
                     DGHGNFGSVDGDSPAAMRYTEAKMSKLSLELLRDIEKETVDFKPNFDESLKEPSVLPA
                     RYPNLLVNGSNGIAVGMATSIPPHNLAEVIDATVYLIDNPECSVDDLIKFVQGPDFPT
                     AAIIMGKESIAEAYRTGRGKVKVRSRAFIEELPKGKQQIIVTEIPYQVNKAKLVERIA
                     ELVKEKRIEGISDLRDESNRNGMRIVIELKRDANANIVLNNLYKHSQMEDTFSIIMLA
                     LVDGQPRVLNLKQILYHYIKHQEDVVTRRTKFELNKAEARAHILEGLKIALDNIDAVI
                     SLIRASKTGQEAKIGLIEKFKLTEIQAQAILDMRLQRLTGLERDKIEAEYEDLIKKIN
                     RLKEILADERLLLNVIKNEITIIKENYSDERRTEIRHAEGEIDMRDLISDEEIAITLT
                     HFGYIKRLPSDTYKSQKRGGRGISALTTREEDFVRHLVTTTTHSRLLFFTNKGRVFKL
                     NAYEIPEGKRQAKGTAIVNLLQLSADEKIATLIPIDGNDENEYLLLATKKGIVKKTKR
                     EEFKNINKSGLIAIGLRDDDELIGVELTDGKQEVLLVTKEGMSIRFDENDIRYMGRTA
                     MGVKGITLSKEDFVVSMNLCSKGTDVLVVSKNGFGKRTNIEEYRSQIRAGKGIKTYNI
                     SEKTGTIVGADMVNEDDEIMIINSDGVLIRIRVNEISLFGRVTSGVKLMKTNDEVNVV
                     SIAKINIEEE"
     gene            complement(4705..6606)
                     /gene="gyrB"
                     /locus_tag="PC466_000558"
     CDS             complement(4705..6606)
                     /gene="gyrB"
                     /locus_tag="PC466_000558"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003226808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HDF2767985.1"
                     /translation="MKQEYGASQIQVLEGLEAVRKRPGMYIGSTSPRGLHHLVYEVVD
                     NSIDEALQGYCSDIYVSINEDGSVLVKDNGRGIPVEIHPKTGKSTLETVLTNLHAGGK
                     FGGGGYKVSGGLHGVGVSVVNALSKWMVAEVYLNGKIYKQTYEKGLPTSKLEVVGESQ
                     DKGTMIQFMPDETIFDEIEFKYETLEYRLRELSFLNKGIKIVFEDKREGQEKRKEFHY
                     TGGLVEYIKYLNKSRTGIHDDIVYIDKKVDDCFVELAMQYTDGYTENIYSFANNINTH
                     EGGSHLSGFKAALTKTVNDYAKRNKFLKENDVNLLGEDIREGLTAVVSVKLPEPQFEG
                     QTKTKLGNSFMRGIVDSVTVDELGSFLEENPSTARIIVDKALRAQRAREAAKKARELT
                     RRKSVLESTSLPGKLADCAEKDPSKSEIFLVEGDSAGGSAKQGRDRNSQAILPLRGKI
                     LNVEKSRLDRILSSDEIKNMITAYGCGIGEDFDIDKARYHKIIIMTDADVDGAHIRTL
                     LLTFFFRYMRPLIDEGYVYAAQPPLYKVTKQKKEHYVYSDKELNILLDEIGRNGVELQ
                     RYKGLGEMNAEQLWETTMNPETRTLLQVTVEDAAIADEVFSMLMGDKVAPRKEFIEEN
                     ARFVRNLDI"
     gene            complement(6607..7722)
                     /gene="recF"
                     /locus_tag="PC466_000559"
     CDS             complement(6607..7722)
                     /gene="recF"
                     /locus_tag="PC466_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HDF2767986.1"
                     /translation="MKLKSLQLVNFRNYKKLHLEFNGKVNLLVGKNGQGKTNIVESIY
                     MLSFGKSFRTNKDKEMVRFNSENLYIGGSFSKYNKYSLIELIIGKDKKGIRINKVPLQ
                     KIQELLGNLNVVIFSPEDLRLVKEGPKERRAFIDKEISQIIPKYYKYLTNYNKTLSQR
                     SRVLKNIHVDEALLDVYDDTLAKYGSYIYILRRDFIKKIANISENMHMNLTNGVERLS
                     IRYKNQINITDEDTIDTVYNKFLAKLSSNRPNDIESKTTRYGIHKDDLNIFINDLDAR
                     LFGSQGQQRTASISLKLSEIELIKNEVEEYPVLILDDVFSELDEARQKLLVNNLSNVQ
                     MFITSAEVSHKKIFDEKNVTIFNIENGDVISIENGGN"
     gene            complement(7740..7946)
                     /gene="yaaA"
                     /locus_tag="PC466_000560"
     CDS             complement(7740..7946)
                     /gene="yaaA"
                     /locus_tag="PC466_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HDF2767987.1"
                     /translation="MTEITIESEYIKLDQFLKLAEIASTGGHAKFLIQEGLVTVNDEI
                     ELRRGKKIKSGDIVKIEGTKIKVL"
     gene            complement(8083..9189)
                     /locus_tag="PC466_000561"
     CDS             complement(8083..9189)
                     /locus_tag="PC466_000561"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HDF2767988.1"
                     /translation="MKIICNQKILANRIGIAQKAINGKTTIELLKGILISTEEGQLKL
                     TGYDAEIGIETYVQAEIIEKGDVVVDARLFGDIIRKLPDSFVEIETDSENNIYINCVN
                     SRFKIKGYAAKEFPKLPELNEEDLYSIPQEILKNMIKQTVFAISQDQTKPVLMGELLE
                     IVDRNLNLVAIDGYRLAVKSCSVDSLTENIKVIIPGKTLIDVNSLLSGEDNVKVGFNE
                     KNAIFIINDTKIITRLLEGDFIDYKKLLPREHNSRVKLNTKELLNSIERASLLSQSEK
                     NNLIKLSIRDKVMAITSNTEKGNVYEEVEIDLDGDYLDIAFNSRYFIEGLKNIDNEEI
                     FIEFTTNVNPCIIKPTDDVNYIYLLLPVRISSNI"
     gene            complement(9431..10753)
                     /gene="dnaA"
                     /locus_tag="PC466_000562"
     CDS             complement(9431..10753)
                     /gene="dnaA"
                     /locus_tag="PC466_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HDF2767989.1"
                     /translation="MMDIVSLWDKTLQLIKGDLTSVSFNTFFKNIVPLKIHLNDLILL
                     APSDFNKDILENRYLHLIEDAISQLSLKKYNIKFVLSEKEVADLNSDSTDLNYRVLYP
                     NLNPKYTFDTFVIGNSNRFAHAACVAVAESPAKAYNPLFLYGGVGLGKTHLMHAIGHH
                     IVSQKKDSKVVYVSSEKFTNELINSIKDDKNEEFRNKYRNVDVLLIDDIQFIAGKERT
                     QEEFFHTFNTLHEANKQIIISSDRPPKDIPTLEDRLRSRFEMGLITDIQAPDFETRIA
                     ILRKKAQLERIDVPNEVMSYIAKNIKSNIRELEGALTRVVAYSSLSNRVISFDLATEA
                     LKDIITTSKNEEINVLRIKEKVSSVFNLKMEDFNSKKRTRSIAYPRQIAMYLTRELTD
                     LSLPKIGEEFGGRDHTTVIHAHDKVSKDIEESEEIKTKIDKIISDLKG"
     gene            11409..11546
                     /gene="rpmH"
                     /locus_tag="PC466_000563"
     CDS             11409..11546
                     /gene="rpmH"
                     /locus_tag="PC466_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HDF2767990.1"
                     /translation="MSKRTYQPKKRQRSKEHGFRKRMKTSNGRNVLKRRRAKGRNRLT
                     H"
     gene            11624..11968
                     /gene="rnpA"
                     /locus_tag="PC466_000564"
     CDS             11624..11968
                     /gene="rnpA"
                     /locus_tag="PC466_000564"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HDF2767991.1"
                     /translation="MDFNRTKGLKKDSDFRKVYKHGKSFANKYLVIYILKNKSDYSRV
                     GISVSKKVGKAITRNRVRRLIKEAYRLNIDEKIKPGYDIVFIARVSSKDATFKDIDKS
                     IKNLVKRTDISI"
     gene            12000..12251
                     /gene="yidD"
                     /locus_tag="PC466_000565"
     CDS             12000..12251
                     /gene="yidD"
                     /locus_tag="PC466_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HDF2767992.1"
                     /translation="MNKIIYILKEISRYLSNLCIYLVRFYQKYISPLKGPTCRFYPTC
                     SQYSIEAFKKYGFVKGMYLTIRRLLKCHPFHPGGYDPLK"
     gene            12283..12990
                     /locus_tag="PC466_000566"
     CDS             12283..12990
                     /locus_tag="PC466_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HDF2767993.1"
                     /translation="MNIIGNFLGLILKVIFEFVNHYGISIILFTILVKIILLPLTIKQ
                     TKSTKAMQDIQPRIKEIQEKYKNKPEKQNEEIVKLYGEAKINPLSGCLPLLIQFPILI
                     GLFSVLREPVAHGVFANKAAFLAADNGFLWIKSLTSPDYVLAVFSGASAYVMQKVMTP
                     KDQLQGSMKVMTYVMAGMSFYWGFIFPAGLTLYWTVSNLFSIAQYYLIMNPLKAKLAA
                     NSKEEKVNEKKPKINKK"
     gene            12959..13588
                     /locus_tag="PC466_000567"
     CDS             12959..13588
                     /locus_tag="PC466_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HDF2767994.1"
                     /translation="MRKSLKLIKSKSKEEAISKAIAELNLKAEDIEVEILENPSKGFL
                     GFIGAKDGTYEIFVIEREVDVAKNFIEVMLKNANVDAKVNVSQKDNLIMVDIEGKEAA
                     SLIGRRGETLDSIQFLTGLALNKINKDSHTRVLVDIENYRSKREESLIRYANKVAREV
                     AKTRKTKKLDYMNPYERRIIHSALQNDKYVITYSEGTDPYRRLVIECKR"
     gene            13700..15079
                     /gene="mnmE"
                     /locus_tag="PC466_000568"
     CDS             13700..15079
                     /gene="mnmE"
                     /locus_tag="PC466_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HDF2767995.1"
                     /translation="MFIDDTIAAIATAPGEGGIGILRISGERALKVAEEIFKSMSGKS
                     IEEYNKRTLIYGNILDNENIIDEVLLAYMKGPNSYTGEDVIEINCHGGFISVKKILEL
                     ILSKDVRLAEAGEFTKRAFLNGRIDLSQAEAVIDVIKAKTDIAHEVAQNQLEGSLSKK
                     IRELRDKVTEILAHVEVAIDYPEEDIEHITYQTLKEKTDELKKEIKKLYDTAESGKIL
                     REGLKTVIVGKPNVGKSSLLNSILGENRAIVTDIPGTTRDVIEEFVNIKGIPLKIVDT
                     AGIRDTDDIVEKIGVEKSKESFTSADLIVMVLDASRKLSEEDIEILEKLKDKQTIVLL
                     NKNDLKQEIEEEKILKYVENNSIIKISALQQEGIEELQDKIESMVYKGSIKNNSSLVV
                     TNSRHKDALSKAYKSATDALIALEQSMPFDFVEVDLKNIWDYLGYINGDTVTEDLLDN
                     IFHNFCIGK"
     gene            15174..17069
                     /gene="mnmG"
                     /locus_tag="PC466_000569"
     CDS             15174..17069
                     /gene="mnmG"
                     /locus_tag="PC466_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HDF2767996.1"
                     /translation="MIKFEAGKYDVIVVGAGHAGCEAALATARMGYKTLIITMSLDSI
                     ALMPCNPSIGGTGKGQLVKEIDALGGQMGLNIDKTYIQSRMLNTAKGPAVHSLRAQAD
                     KFKYHEEMKKTLEDEPNLDIAMDEVVEILHEGNVVIGVGTKLGCSFKSKAVILATGVY
                     LNSKIYMGEVAFYEGPNALGYAKYLTDSLVELGLRMRRFKTGTPARVHRDSIDFSVMS
                     LQEGDEKVTPFSFMNENIEKKQEPCYLTRTTEETQKVILDNLKRSAMYSGVIESTGPR
                     YCPSIEDKVVRFSDKTSHQLFIEPEGLNTKEMYIQGISTSLPFEVQLDMYKTIKGLEN
                     CKIMRPAYAIEYDCVDPTQLKISLEIKGVENLFSAGQFNGTSGYEEAAAQGLMAGINA
                     VRKIEGKEPFVLDRSEAYIGVLLDDLVTKGTNEPYRMMTSRAEYRLYLRQDNADMRLT
                     QKGYDIGLVKKDRYERFLNKKAAVDKEFERLKNERVTPKEVNSLLEEKGATPIKVGIS
                     LYEFLKRPEVTYELLEELGKGAGEDVSREVKEQCVIITKYEGYIEKQLKQIDQFKKLE
                     NKKLDEKINYSSIEGLRLEARQKLDDIKPISIGQASRISGVSPADISVLLIYLEQVRR
                     TRGGKGE"
     gene            17062..17781
                     /gene="rsmG"
                     /locus_tag="PC466_000570"
     CDS             17062..17781
                     /gene="rsmG"
                     /locus_tag="PC466_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HDF2767997.1"
                     /translation="MNNIELLKNGIEGFNIDTNDSMLEKFKIYREILVEWNKKMNLTG
                     IEDEKEVYIKHFLDSISAVKNGYIKNGMSIIDVGTGAGFPGIPLKICLDSLELTLLDS
                     LNKRINFLEEVSRVLELDNITFIHGRAEDFGKNEDYREKYDVATARAVAGLPILMEFC
                     VPFVKVGGYFICLKGPNANLELEESQKAIDVLGLEYIEKIDVELPEVDLNHNILVFKK
                     VMETPVKYPRKAGRPAKNPIK"
     gene            17956..18741
                     /gene="noc"
                     /locus_tag="PC466_000571"
     CDS             17956..18741
                     /gene="noc"
                     /locus_tag="PC466_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid occlusion protein"
                     /protein_id="HDF2767998.1"
                     /translation="MEDKRVMEIPIEDVVPNPYQPRKIFSQVSLEELSNSIKVYGIIQ
                     PITVRAKDGKYELIAGERRLRAAKLAELKTIPAIINNMNDESSAVLALLENLQREDLN
                     FIEEAIGYENLIKEHAFTQQQLAEKLGKNQSTVANKLRILKLPNDIKMKLIENNLTER
                     HARAFLKLPSEDLMQSVLDKVIKNELTVKKTEKLIQDVLEETKVQEEPDKKQNIKGAM
                     SIRIYINTIKQAFDAISNTGIDAKYNEIDKGDYMEVVVKIPKK"
     gene            18876..19649
                     /locus_tag="PC466_000572"
     CDS             18876..19649
                     /locus_tag="PC466_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HDF2767999.1"
                     /translation="MGKVIAVFNQKGGVGKTTTNVNLSASLGTLGKKILVLDLDPQGN
                     TTSGYGINKNEVENTIYEIMLDGLHIKEAIISTEFENVDVVPSATELSGAEIELTSKT
                     NREYILKNSIKAVIDEYDYIFLDCPPSLGMLTINCLTAVDSVLIPIQCEYYALEGVSQ
                     LMETIKLVKSRLNADIEIQGVVLSMFDGRANLSIQVVEEVKKYFKGSVYTTLIPRNVR
                     LAEAPSHGKPVIYYDKRCRGSVAYLELAEEFIDLEEEEW"
     gene            19651..20514
                     /locus_tag="PC466_000573"
     CDS             19651..20514
                     /locus_tag="PC466_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HDF2768000.1"
                     /translation="MENKSKRSNRLGRGLSALIPEIKGETSEKEIVNIDIDKIYPNEV
                     QPRKQFDEEKIKVLSDSIKNYGVLQPIVVKMDENNKYMIIAGERRFRASKLANKNQIP
                     AIIKDIDMKDIMEIALIENLQREDLNSIEEALAYKSLIEHYNVTQEEISEAVGKSRPH
                     ITNTLRLLNLGQDVIEMIDSGRITAGHGKALLRIADKDLQLQIAKKIEEEELSVREVE
                     NIAKKISENKQEEPKKSKPKDVFILDVEDKLRNIFGTKVNISKGKKKGKIEIEYYNDD
                     DLNSIVSMLLE"
     gene            20547..21689
                     /locus_tag="PC466_000574"
     CDS             20547..21689
                     /locus_tag="PC466_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HDF2768001.1"
                     /translation="MIYLDNAATTYPKPERVYNAVLDCMKNYCANPGRAGHKLAMRAA
                     REIYDTRENIAKLFNVSNPMNIVFTSNATDSLNLAIKGVLQEGDHVITTSMEHNSVIR
                     PIKALEKRGIENTVVKCDYEGFLDYEDLEKSIKSNTKLIVTTHASNVCGTLIDIKKVG
                     EIAKKHNILFLVDASQTAGVYDIDVNECNIDMLAMPGHKCLFGPQGTGILYVREGLNL
                     NILKEGGTGSKSEEIVQPELFPDKYESGTHNTPGIAGLNQGILFIFERGINNIRQHEE
                     ELCQYMIDKLEEVSDIKIYGPKDSKKRASVIALNIGDMDSGEVTFLLDSDYNIATRSG
                     IHCSPLAHTTLGTLKQGAVRFSIGYFNTKDEIDKAVEALKKISKNK"
     gene            complement(21823..22398)
                     /locus_tag="PC466_000575"
     CDS             complement(21823..22398)
                     /locus_tag="PC466_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GerMN domain-containing protein"
                     /protein_id="HDF2768002.1"
                     /translation="MKNKKIMLVLSILSISIFAVGCTNAQNGSDTSKKETKSNTNVEQ
                     PKEENNTEKEVPNNKAKPTPKEETKTQSATIYSFDVDKTDLIENKVDLNKIDENTLFE
                     ELQKLKVVPESAKLNSFTTKDIDGVKTGILDVSSDFTKSNLGSDAETLMLDSVARTYI
                     KNMNVEQIKITVDGSNYESGHIVLEEGDYLK"
     gene            22658..23950
                     /locus_tag="PC466_000576"
     CDS             22658..23950
                     /locus_tag="PC466_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HDF2768003.1"
                     /translation="MEILSLGEKIKKLRKEKNMTLKELAGDRITAAQISHIERDKSHT
                     SYELLEYLGDKLDVSVEYLLETKEMQSKKITDNLILQSEIYIKENELNKAEDQIKEVL
                     DICKRYDLMENYGRCNFLMANINLKKSNYNDAIENFEKALYFFIKNSDSENILKCYLN
                     IGKIYMQEDFYKGAISHFNFAEEILSENKFEDVNIHKELYSKMAYCYIKLDNPNMSLK
                     YIEKINEIDNRNDRKEDVDILVLKANNMLEIGKYEESRDYFKKALKILESEDNKTGLA
                     NVYLTICDVYRKIGETDRVLEYSQKVYDIKKNDEDEYMMSGLFKIIEAYIDKEDYDLA
                     RKYCKIALASSIKNKNKFNEYKALRFYANMYKNQNEVTLAIEYLIKCIKIVSDLGNNR
                     ILANLYIDLGQLYSNISKEKELEYYQKGVFMYKNLEIM"
     gene            24055..24657
                     /gene="yedF"
                     /locus_tag="PC466_000577"
     CDS             24055..24657
                     /gene="yedF"
                     /locus_tag="PC466_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase-like selenium metabolism
                     protein YedF"
                     /protein_id="HDF2768004.1"
                     /translation="MSIKIDARGLACPKPVINTKRELDNLEEGVVVTIVDNETAKENI
                     LKLAKSLSCEANIVDEKENFISIEIRKGKNILDKQNVVDNKESELDNTCIFISSDKMG
                     LGNDELGKVLIKGFIYTLTESKPYPKYVLLVNGGVKLSAENEETIENLKILENMGVEV
                     LSCGTCLDYYNLKDKLQVGTVTNMYTIVETLKNASNTISI"
     gene            24730..24993
                     /locus_tag="PC466_000578"
     CDS             24730..24993
                     /locus_tag="PC466_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3343 domain-containing protein"
                     /protein_id="HDF2768005.1"
                     /translation="MNQMYIVSFNSTHHAIRSEKLFGENSLKVMALPTPREITASCGI
                     SIKFSFEDMEKIKTILVENNVDIKGIYCISKLENGSKEVEKLD"
     gene            25008..25193
                     /locus_tag="PC466_000579"
     CDS             25008..25193
                     /locus_tag="PC466_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HDF2768006.1"
                     /translation="MPMDLKIGDIVELKKQHACGCKEFEIIRTGMDIKIKCTKCSRLI
                     MLDRETLEKRVKKLIKK"
     gene            25296..26492
                     /locus_tag="PC466_000580"
     CDS             25296..26492
                     /locus_tag="PC466_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HDF2768007.1"
                     /translation="MAVKYAKRMQGLQGSEIRELLKLTQQPQIISFAGGMPAPELFPV
                     EEMKKVSVAVLEENGRSAMQYTTTEGYEPLREKIAARMNDKNKTNVNKDDILVTSGSQ
                     QGLDFAGKVFIDEGDVILCESPSYIGAINAFKSYQPKFIDVPTDSDGMIMEELEKILE
                     TTDRIKMIYVIPDFQNPTGRTWPLERRKKFMEIVNKFEIPVIEDNPYGDLRFEGETLP
                     SLKSMDTKGLVIFLGTFSKIFCPGYRLGWTCASPEILSKFNFAKQGADLQASTISQME
                     VSKFMDMYDLDAHVDKIKAVYVKRRDVMLKTMEEEFPEGLVFTHPEGGLFTWVELPSN
                     LNAKELMPKCLEKNVAYVAGGGFFPNGGRENTFRLNYSNMPEEKIIEGIKNIAAVLKE
                     AMGVEA"
     gene            26706..26984
                     /locus_tag="PC466_000581"
     CDS             26706..26984
                     /locus_tag="PC466_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HDF2768008.1"
                     /translation="MRNYELVYVVKPNSDEEVREAILNKVKEVVATDGEIVKVDTWGT
                     KKLAYPIAKFTEGFYVLVNFKSAVDVPKEIDRNLKINENVIRHMIVVA"
     gene            27021..27455
                     /gene="ssb"
                     /locus_tag="PC466_000582"
     CDS             27021..27455
                     /gene="ssb"
                     /locus_tag="PC466_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HDF2768009.1"
                     /translation="MNQVVLVGRLTRDPELRYIPGTGTPVASFTIAIDRDYVKKDGSK
                     ETDFIPVEVMGKSAEFCANYITKGRLVALQGSIRVDNYQTQSGEKRTFTKVSTRSVQA
                     LDSKNKSENSYRESAPAFEPSFEPQGLDPQGFQAIDDDDIPF"
     gene            27474..27701
                     /locus_tag="PC466_000583"
     CDS             27474..27701
                     /locus_tag="PC466_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HDF2768010.1"
                     /translation="MMNKKRRKKKRVCQFCADKNAKIDYKSTQRLQKYITERGKILPR
                     RISGTCAKHQRELTVAIKRARNIALLPYTLD"
     gene            27844..28164
                     /locus_tag="PC466_000584"
     CDS             27844..28164
                     /locus_tag="PC466_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HDF2768011.1"
                     /translation="MKIDKGSEITRNIKIIEWMKTEILMSVSDLFNLLFKGVKPLDEA
                     IQDTLANIIMITYLLAKRLGISFRDVDYKVKEKIKIGIDEDHSVERWYGDLSNLKKHM
                     DNRE"
     gene            28172..29128
                     /locus_tag="PC466_000585"
     CDS             28172..29128
                     /locus_tag="PC466_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YybS family protein"
                     /protein_id="HDF2768012.1"
                     /translation="MNNKIRLSKAMSIIVLAIIIALVIAYIPMLGIFSMLAAVPYVII
                     GAITDRKYSLISILVTFCVLILFADISYALNICIMYSLPGIVIGKMLKRSFEQEDSNK
                     FEPIYGGTIIFVLSMLVYFFVLKTFLNVNLLDEVSKMISEIVNIQKNSFSATELKVFD
                     KMKPDEIVSYFTNMLPMMLFLQGLLSAFVTYYLSVFFIKRITKMNIRFPKFADFYLPG
                     NAILTTFLLYLLVLFIQIIGSKLYTELIMTNLQLVFNLMFVIQGIAVCIYFLKKWIRQ
                     GPNKIMFFSGIILCLFGFMGISFVGMVDSIIDFRKVRSYKST"
     gene            29139..31133
                     /locus_tag="PC466_000586"
     CDS             29139..31133
                     /locus_tag="PC466_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HDF2768013.1"
                     /translation="MSNKQTFKLNMPEINLYIIVIGISSIILLYYNLYVGCLFFCIFV
                     YMVFHNWRTTNIRRHEWTEYIQNLSLDIDETTKKAIINLPIPLCILEFDGNISWYNGK
                     FYDMIGQKDLLDKNIEDIVKNLNLRKVLNENKEMYTEINYKEKEYTIIYNVIKNDQEK
                     NPKYLMILYWIDKTEYLKVKQNYDDEKNAMMLIQVDGYDEVLKSAAEDKRALINVEVE
                     KILSALELNSNGALRRTSKDKFFLVMHKKELKKLEAEKFSILDTIRHIDYGNNLPVTI
                     SIGIGIDGDTLNENLKLATGALDLALGRGGDQAVVKTKDKFVFYGGKSKAVEKKTKVK
                     SRLIGHALREVIQQSDQVYIMGHKYPDMDAMGAAVGVYDICKSCNKTANIVLQSVNES
                     IEIFINKINENNYYKKLFIGKEEAIDNCTKNTLVVVVDTHRPNYTECEELLKLSEKVV
                     VIDHHRRGVEFINDAVLLFHEIYVSSTCEMVTELVQYMDEDVTINKLTAEGLLAGISL
                     DTKNFAFKTGVRTFEAASYLRKVGADTIEVKKFFNSDVKDFIIKAEIIQSTKIINNRI
                     CLAYSSTEIDSINVIIAQTADELLNIKEVEASFVLGEKDDTIFISARSLGQINVHVLM
                     EKLGGGGHIDIAGAQLKNVSLKEAYKMVNKIIEEYLEEEE"
     gene            31134..31583
                     /locus_tag="PC466_000587"
     CDS             31134..31583
                     /locus_tag="PC466_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HDF2768014.1"
                     /translation="MKVILLKDVKGTGKKGEMKEVSDGYARNFLFPKKMAVQADSVAI
                     KELNEKNKSKEIKAQKEYEEAVLLGKQMEEINIEIYSKAGEGGRLFGSITSKEIAEQL
                     KKQKDIDVDKRKILLDEPIRSLGSTFVEIKIHQKVTTKIRVDVKEKQ"
     gene            31602..32930
                     /gene="dnaB"
                     /locus_tag="PC466_000588"
     CDS             31602..32930
                     /gene="dnaB"
                     /locus_tag="PC466_000588"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HDF2768015.1"
                     /translation="MEDMTRIPPHSVESEQSILGSILLDKDAIITVTETIKPDDFYKE
                     AHKIIYECMITLSNKGEPIDLITLTEELRKQGHLNDIGGISYITSLSTIVPTTSNVKY
                     YADIVKEKSVLRKLIKASNEIINLGYSGATKIEDVLEQAEKSIFDISQEKTSDDFKSI
                     NLVLMDAYDMIEKLYTNKSDVTGITTGFKDLNKKINGLQRTDLILIAARPAMGKTAFS
                     LNLVQNAALKGDASVAVFSLEMSKEQLVQRMLSSQSSVELKKIKTGTLNDNDWPRIID
                     AMAVLSDAKIHIDDTPGIKISELRSKCRKLKIEKGLDLVLIDYLQLMEGEGNNESRQQ
                     EISKISRSLKILAKELNCPVVALSQLSRAPEQRADHRPMLSDLRESGAIEQDADIVMF
                     LYRDEYYHADSESKNIGEVIIAKNRHGETGSVELVWLGEVQRFGDKLRDL"
     gene            33135..33443
                     /locus_tag="PC466_000589"
     CDS             33135..33443
                     /locus_tag="PC466_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768016.1"
                     /translation="MEKISLKYIYPNIIKVLDEINLFRVIDNNLRESIVVYANNVDNQ
                     YHINMTNTNFGNIINICKLEKLLDVDKFMEKVIKYEKEIIEKEEFSKIEEYMLNIGEY
                     "
     gene            33525..34814
                     /locus_tag="PC466_000590"
     CDS             33525..34814
                     /locus_tag="PC466_000590"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HDF2768017.1"
                     /translation="MKTVAIVGSQWGDEGKGKVIDYLATQADVVVRGQGGNNAGHTLV
                     VEGKKYALHLIPSGVLNPNTVNIIGNGIVFDPKGFLEELEMFKTDNISTENIKISDRA
                     HVIFPYHKELDALSEEARGDLKIGTTKKGIGPCYMDKTERSGIRICDLMDKDKFAIKL
                     KAQIDAKNKIVKNIYGKEELFDFETIYNEYLGYAEQIRKYVADTSVIVYDAVRAGKKV
                     LFEGAQGTLLDLDLGTYPFVTSSHPTSGGFAIGAGIGPNMIKDVVGIVKAYTTRVGEG
                     PFVTEQINETGDKIREQGHEFGVTTGRPRRCGWFDAVIVKYAARVNGLTSISFMLLDV
                     LTGFDKIKVCTSYKMGDKIITDFPASLDDLAKCEPVYEELDGWNEDITQIDNFDDLPE
                     NAKKYVAKIEELVGVSVDMVSVGPNRAQTIIRRNIFA"
     gene            35140..35215
                     /locus_tag="PC466_000591"
     tRNA            35140..35215
                     /locus_tag="PC466_000591"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35173..35175,aa:Lys,seq:ttt)
     gene            35222..35296
                     /locus_tag="PC466_000592"
     tRNA            35222..35296
                     /locus_tag="PC466_000592"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35255..35257,aa:Glu,seq:ttc)
     gene            35301..35376
                     /locus_tag="PC466_000593"
     tRNA            35301..35376
                     /locus_tag="PC466_000593"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35334..35336,aa:Val,seq:tac)
     gene            35410..35484
                     /locus_tag="PC466_000594"
     tRNA            35410..35484
                     /locus_tag="PC466_000594"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35442..35444,aa:Thr,seq:tgt)
     gene            complement(35867..36859)
                     /locus_tag="PC466_000595"
     CDS             complement(35867..36859)
                     /locus_tag="PC466_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF2768018.1"
                     /translation="MNEDKIRKILAKYAKRRDDNELLLEHRKNEVYNRIPEIKSIDDE
                     ISKIGLSLAKIVLLNPKSKDEIVKKTKENIESLKVKKEKLLSESNIPLDYLEIKFQCI
                     SCKDKGFLPNGEKCSCLKQEIVNEAYKMSNLDRILSQENFSNFNLNIFSPKKGSDGEI
                     SPRENMLNNLSICENFVHDFKKDNSENLLFYGSTGLGKTYMCNCIAKELLDKGNVVIY
                     QTSFRILDILEDYKFRRDTNNQISEDNYKNLFDCDLLIIDDLGTELNNSFTSGEIFNI
                     VNTRLVAGKKIIISTNLTPSQIGNTYTQRTLSRILDKFRILEFTGDDLRWERFK"
     gene            complement(36868..37926)
                     /locus_tag="PC466_000596"
     CDS             complement(36868..37926)
                     /locus_tag="PC466_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HDF2768019.1"
                     /translation="MFFKESNEIDLGEITIPNIFIDIFMPMADGLYVKVYLLGYRQAC
                     DITSNPKFDNNSIAKNLNIPLSDVLSAWKFWEEKKIIKIHDNGEYDNFNYSIEFLDLK
                     NFYIENILSNNSSIKSNTDKVVSTSENPSIRKMFNSINKIVGRYLDPSEKMSIMDIMN
                     KYNMSPDMILCAYEYVKDKTGTSKPVKYIEGIIRNWYDSNLYTPKDVEESFLVRSERY
                     ILYKTIFNELGFSRQPSKSEKELMDTWFDKFNMDIDLIINACSKSKNISNPSISYING
                     IIKNWNEKNIKNLNDLKQKEEERIVKENINKKQINTTQNNNTYKKTKFHNFNETFTQY
                     TSDELDEIIKKSQKEKFK"
     gene            38051..39514
                     /locus_tag="PC466_000597"
     CDS             38051..39514
                     /locus_tag="PC466_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HDF2768020.1"
                     /translation="MVIKFNQKVRRTLSVAILFMVLIIGCFIEKDDSLETYKEKTNSK
                     INQYNMDVIFDDETKRLMCNQNVDYINNTKSNIDKIYFHIYPNAFSKKDFAPFEKSEM
                     TRAYPNGFNEGYIDIKNILNNNSKMEYKIKGDKNDILEIELGKELKPNERMSLDIKYN
                     VKIPNSIGRFGYGENTINVTNWFPIACVNDERGWNLKSYETIGDPFYSETSDFHVKLL
                     IPNKYKIAHTGKLIDDKHDNKKMLYEIEAENVRDFAFILSSKFDVNKVDSKGVAINTY
                     NLNKKLSKKATEVAKDSINIFSELFGKYPYKEFSVVASDFFIGGMEYPMLVMIDQSLY
                     NEKNEFLLEYVIAHETAHQWWYSAVGNDEISEPWLDEALTEYSTIVYFEQKYGKDMAN
                     KLIKTMEIQTKSYLSENIFKPANEYKNSTEYSLNVYTKGAIAFNEIRKEVGDKVFFET
                     LNEYYNKYKHKNANGRAFVELWNSKGVDINKIISECK"
     gene            39616..40413
                     /locus_tag="PC466_000598"
     CDS             39616..40413
                     /locus_tag="PC466_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF2768021.1"
                     /translation="MLKYCSVGSGSSGNCHYIGYKNTNILVDAGLSGKRITTGLKDIG
                     VDADKLKGIFITHEHVDHIKGAGILSRKFDIPVFANIKTWCSMKDKLGDIKDKNMKVF
                     ENDKTYSLGDIIVRPFSIEHDASDPVGYNFYTESDEKMSIATDIGCITQNIKKHLYKS
                     KLVVLESNYDPNMLMMGSYTYALKKRVMSSTGHLSNEDAANFCVELINEGTESILLAH
                     LSKENNFPELAYETSKGVLASNDIVVGQDVKLDVLSRNDVSNVYEMK"
     gene            40426..42528
                     /locus_tag="PC466_000599"
     CDS             40426..42528
                     /locus_tag="PC466_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC/EAL
                     domain-containing protein"
                     /protein_id="HDF2768022.1"
                     /translation="MLKRNFENVEDNKILYSIKQGMILAIPAIMTGSTALVILNLPIK
                     AYQEYLSGLFNGEVTNILNFINDSTLGIISLIILLTISYSYGKIYGSKYTVLVPIVAM
                     CSFLVFSHGNELNSYIEIFKTKWLFTSIIVSMTSSVLFVKLTESFVTSVKFHTEGADA
                     DFNMVVSAIVPFIIVVFLFSIFRVIMISLIGSSNFQDIFYNLFSNVFNKMGTNLMSAL
                     LFIFLMHFMWFFGIHGSNVLDTVAKNLFENSMAININLVNNNQLPTEIFTKTFFDTMV
                     LLGGCGSLLCLVIAIFLSEKRINVRKLAKIASIPALFNINEMLVFGIPIVFNYIMFVP
                     FVITPIILTITSYVAMSTGIVPCTVSAVEWTSPIFLSGYMSTGSIRGSLLQVFNLCVG
                     VMIYIPFIKMSQNRYTYMFKNNIENLTNLLKRYELTGEQPNLLNHNGKIGSISKMLAS
                     DLKFAMKRGEIELFYQPQVNYNGNVVGAEGLLRWKHSIGGFIYPPLVIILAKEEGFLD
                     ELGEYIINKACIDLKKSEKLLRNPVKFSVNISPDQLDDPKLPEQIKNIISSNDINPNM
                     LGIEITEQIALSGSQIIIERINAIHNLGIKLIMDDFGMGHSSLIYLQNNNFDIVKLDG
                     SLVKEILTNKRSSEIIMTIVNLSKNLDFDIVVEYVENIDQRDKLYGLGCEIYQGYYYS
                     KAIPFEEFVEYANQEKEI"
     gene            42596..43075
                     /gene="rlmH"
                     /locus_tag="PC466_000600"
     CDS             42596..43075
                     /gene="rlmH"
                     /locus_tag="PC466_000600"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HDF2768023.1"
                     /translation="MNISIVVVGKIKEKYLKLGIDEFKKRLSKYCKLEIIELDDEKAP
                     ENLSVKEMEIIKDKEGKKILGKIKHNSYVIVLAIDGKGLSSEELAKTMSDLAVRGNSS
                     LCFIIGGSLGLSDEVLGRADYRLSFSKMTFPHQMMRLILLEQIYRAYRINNGEPYHK"
     gene            43224..43535
                     /locus_tag="PC466_000601"
     CDS             43224..43535
                     /locus_tag="PC466_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2768024.1"
                     /translation="MIKIMLACSAGMSTSLLVTKMESAAKENGIESQIWAIPESTIQN
                     EIEKCDVLLLGPQVRYVLPKAQEIAKPYNIPVEVINMMHYGTVNGEAVLNRAIELNNT
                     K"
     gene            43583..43900
                     /locus_tag="PC466_000602"
     CDS             43583..43900
                     /locus_tag="PC466_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HDF2768025.1"
                     /translation="MDEKIIEISFNIIGYAGEGKGLAFEAIKEAKNGNIEKAKELLKE
                     SKEVINKAHRYQTELIQNEASGNRTEISVILIHAQDHLMNGMNFQQLAEEIVDLHLKL
                     QDK"
     gene            44113..44814
                     /locus_tag="PC466_000603"
     CDS             44113..44814
                     /locus_tag="PC466_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2768026.1"
                     /translation="MLRNQPLYIQVVDILKQKILNNEYKIDENIPTERELEQEFGVSK
                     ITIRKAIEILESEGYVEKKSGKGTKVISNSLFNKLSKAESFSSILLSKGHKLSKKTIS
                     IEKIINDTNSQVFSIFGEKCSKITRMYYLDSKPYIFFTHYIPFDENLTVESFNNESSL
                     YMYLYRRNINITRFEDEFFIEESELEVSKALNLAKDILLGRKRKTYDENDNIVELSFA
                     RYNTEVQNYVIKYEI"
     gene            45038..46339
                     /locus_tag="PC466_000604"
     CDS             45038..46339
                     /locus_tag="PC466_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF2768027.1"
                     /translation="MEKFASFLERKIMPVAAKISNQRHMRAVRAGIIATLPLTIVGSF
                     FTILLNIPIDAYMDFIAPFKATLDIPFRYTVGFLSLYATFGIASSLAKSYDLDTTGVG
                     MLAVMAFLVSTIVPTQVVEPVGGVIEAGRWMDMAKLNSPSLFGAIVTSLITVEIYRFM
                     KEKNITIKMPAGVPVEVSNSFTALLPTAVILMLFWVIRHILGFDISVALSAMLSPLKG
                     FLSGNSLGGGLLTVFLITLFWVLGIHGPAIMGPVIRPIWDMSIAENITAFTEGVSAHA
                     MPNIFTEQFLQWYVWIGGAGATLALVVMFMFSKSQYLKSLGRLGFLPGLFNINEPIIF
                     GAPIVMNPILGIPFIIGPIIMTILSYVLTITGVIPMMVARLPFAMPAPIAAVMSTNWS
                     ILAGILVLINFVISFAVYYPFFKVFEKQQLQREQEEMSENL"
     gene            46476..47570
                     /locus_tag="PC466_000605"
     CDS             46476..47570
                     /locus_tag="PC466_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HDF2768028.1"
                     /translation="MERRLGISVYPEHSNMEDDKAYIKMVSKYGFKRIFMCMLSITRP
                     KEEVKKHFKEIITYARELGFEVILDIAPNIFDILQISYDDLTFFSELNASGIRLDYGY
                     DGSKEAMISFNPYDLKVELNMSNDVAYLDNIITYKPNVNNIYGCHNFYPQRGTGLPYD
                     FFVRCSNRFKKYGIRTAAFVNSKYATIGPWNINDGLCTLEMHRNLDIATATKHLFATG
                     LIDDVIVGNAYASEDELKRMSEVNEYQVVFNVVAKEKTSEVEKIIMVNEQHFRRGDIT
                     NQVARSTEVRKKYAKENFPKHDNKNIFKRGDVVIGNDDFGKYKGELQLILQDCTDERK
                     NKVGRIKEDEIILLDFIEPWSKFKIILEGE"
     gene            47572..48705
                     /locus_tag="PC466_000606"
     CDS             47572..48705
                     /locus_tag="PC466_000606"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase/deacetylase family
                     metallohydrolase"
                     /protein_id="HDF2768029.1"
                     /translation="MKIDILIKCGKTVDKSIIDIAILDDKIIEVKNHIDDSKYQAKQI
                     INLDGEKFISAGWIDIHTHCYERLDLYKDYPDEVGIKSGVTTVVDAGTTGALDIGEFY
                     EDTKKYKTNVYALINIAKQGITSQDELSNMMNIDEYELKNAVRKYKDFVVGIKARMSK
                     SVVISNDVEPLKVAKRIKNELNLPMMVHFGSSPPTIEDIFDYMEKGDILTHIYNGKPN
                     GILRGNEVKKEIIEAKERGIILDVGHGTESFSMDIAMKSKDAGIFPDTISTDIYIKNR
                     INGPVYNLSTTMEKFIYMGYSLEDIIDKVTKNAADAISLKNKGLIKEGYDADLTIFDV
                     VNEEKELQDSLNKSVITSTSIKPRAVVVNGEYLNIGNSIEENE"
     gene            48723..49832
                     /locus_tag="PC466_000607"
     CDS             48723..49832
                     /locus_tag="PC466_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DgaE family pyridoxal phosphate-dependent
                     ammonia lyase"
                     /protein_id="HDF2768030.1"
                     /translation="MSSIFEKYSVRRVINASGKMTILGVSTVDKEVIEAIGEGCKNFL
                     IIEELVNKTGEYIANLLGCESALIVSSASAGIAQSVGAMIAKDDMSLVYNVNNPKKQV
                     KREIIIPKGHNVDYGVPVEVMIRLGGGEVVEAGYANMCNKEHIIREINENTAAIMYIK
                     SHHCVQKSMLSVLDAVQVAKEYNLPLIVDAAAEEDLNVYYELGADLVIYSGAKAIEGP
                     SSGLVIGKKKYIDNVKLQSKGIGRAMKIGKENIVGLTCAIERYISNDKVTLKEMEDKL
                     NPFIDKINTIKGVSASITRDSAGREILRGEINFNEDIINKSTQQIINELRSGEIAIYT
                     RDYKANEGKIEIDIRSVTGSDLDNIYNRIKNIVES"
     gene            49897..50637
                     /locus_tag="PC466_000608"
     CDS             49897..50637
                     /locus_tag="PC466_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KDGP aldolase family protein"
                     /protein_id="HDF2768031.1"
                     /translation="MNCIPQYYKNRVCLNVLAGSIKNAKEVYDACDGHVLVGVLSKNY
                     STVEAAIEDMKKYSKEIDNAISVGLGAGDPNQSNMVSQISKELQPQHINQVFTGVATS
                     RALLGQNDSIINGLVSPTGKPGFVKISTGPLSSKEKDGIVPIETAIAMMKDMGGSSIK
                     FFPMGGLKTKDEYIEVAKACAKHNFYLEPTGGIDLDNFKEIVQIALDAGVEKVIPHVY
                     TSIIDKETGDTKVEDIGVLYKIMKELLG"
     gene            50642..51634
                     /locus_tag="PC466_000609"
     CDS             50642..51634
                     /locus_tag="PC466_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HDF2768032.1"
                     /translation="MNILAFGEIMMRLSVPDYKFLTQTNELNYIITGTGLNILSGLKN
                     FGYNTYMLTKLPNNNVGKASSANIRKLGVKDDFITYGGNHIGVYFLENGYGERPSEVT
                     YLNRLNSSFCESKLQDYDIDKCLEEMDIVHICGIAMQLTDSVKKIALELARKSYEKGI
                     KVFFDFNFRQSLNPERTYDDLVNDYKKILPYCHGLFASYRDINKILNIDSLNIKSSSE
                     LIKKEYDIDIVAGTMRRFDDMNNRFIKGYISNDDGYFESREYKLEIYDRVGAGDGYVA
                     GIIYSYLENMKSEDIVEFGVASSVLAHTTYGDNSLVSTGHVLRLMNNEKIDILR"
     gene            complement(51821..52702)
                     /locus_tag="PC466_000610"
     CDS             complement(51821..52702)
                     /locus_tag="PC466_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDF2768033.1"
                     /translation="MNTKQLEYFISVAENLSFTKTAEKFYISQTAVTQQIKALEEQIN
                     VTLFTRSKRHVELTPAGKVFLSEARTIIKNINDAIAKTQQFAHGFFGTLSIGTLIGYE
                     KNKLQQYLKEFSNTYPNISMDICTNEITELLNLVKNNSMDLAFVINPENQPLKDFEYK
                     TVERYSLVALLPPGHPLYNEDSIDLIELQHDKFIFVKETGDEYGQKSMIQNRYREAGF
                     VPNVVQRSNNLNTIESLVSSNMGISILPSFCVTDTMIERDIAIVPIKEVENRIEVVVV
                     WNKKNTNPALEKFISII"
     gene            52975..54363
                     /locus_tag="PC466_000611"
     CDS             52975..54363
                     /locus_tag="PC466_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768034.1"
                     /translation="MEDKFYAKGNGNNGYIKNLEVCSFNNLDGTCGMFQMALYKRDEK
                     YYLYGCCFGGNKKNGVMISDITDPYNPQFIKHFQMLDPKEYPTTTTPKIQIADDLMIV
                     AMSCGSGPGALVDQAKLANIKCEAGIRIYSLKEDPLNPKFLGYWDCGLKHVMGVHRFM
                     YNGGRYVHLSSDCVGFEGLIYRVIDIINPNNPVEIGKWWRPDQYADGYPNRTFDAGAP
                     HCPEFMDKGWLHGPPFVRDGKAYCGYGGAGLVVLDVEDLTRPRCLGELPFMPAFSSRL
                     AGARTHTALPLPGRDLVVVQNEGERFQFFKPDNITDVQAMNNIHMVDVSDPTKPTLIA
                     QFPYPEVPKDFPYPNFNVAGLGKAGPFGPHNLHEPMDNKPWLEQRGDRVYCCYFHAGL
                     RVYDVSDPYYIKELAYFIPPNPNKTPEESYFPGFPGPRLAVTEDLIVDDRGYIIIDAL
                     DDGFYILKMKED"
     gene            54391..55344
                     /locus_tag="PC466_000612"
     CDS             54391..55344
                     /locus_tag="PC466_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HDF2768035.1"
                     /translation="MKILGISFGTKNGNNDTMCKVALKGAKEAGAEVEFIQMSSINIK
                     HCTGCCACVKTLLSGKGSMCVLKDDFEWLLDKMKDADGIVVSDPIFEEGASGLFHTIM
                     DRFGPRADRGNNIIGTKVAEAIGGKIPDSRMLNDKVISFMGIGGSDWGTRVQCEHAML
                     ALIPMWKVIDNAWFPWAKELVMDDTRLVQVHQIGLNIVEAAKDFEKASYQGEEGVCPH
                     CHNRLFYLESGTKKAICALCGIVGELDTISGKTIFSFPEEQLGHAHDTLPGKFIHGDD
                     IKKMEGHYAEVRKTQEFKERKTSYNFIEPLTKEKQAGVSLG"
     gene            55404..55628
                     /locus_tag="PC466_000613"
     CDS             55404..55628
                     /locus_tag="PC466_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768036.1"
                     /translation="MNEKPSFKQIEIILAVIFLVLTYYKIGLTPAFIVIFIPLYLSYF
                     AVSMIVNQIAIKLLEIRQAREATNYNIGNG"
     gene            55621..56133
                     /locus_tag="PC466_000614"
     CDS             55621..56133
                     /locus_tag="PC466_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1097 domain-containing protein"
                     /protein_id="HDF2768037.1"
                     /translation="MDRKKKEILTLSMGIALLPPLWAVLAPYIGIKTGAVALICAGLY
                     VTNGNKQKDGLKIMFGFWCGDLWAVLAILIMGYMNFNQNLELFLTLSILGFFAVVIAS
                     LFEKIIFLPSWLCGWAIGLTIMTGENIINLQDICIQIAVAMAVGVWYVGAGVDLFTIY
                     ILSKDKKKGN"
     gene            56165..57019
                     /locus_tag="PC466_000615"
     CDS             56165..57019
                     /locus_tag="PC466_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA hydrolase"
                     /protein_id="HDF2768038.1"
                     /translation="MAMGFEFKIMRSLIYVGLAKEEYRPKLMDWLYRHHIPDSISTFG
                     PYCTKYAFYQAYPTPNEGERFGARKMQLTEHYWLVDEHMPEMANRIMTEYMPMDVLRW
                     QGCIPDVENKRVHENAESGDAGRAVGGDNGCPPFIFAFVPINWEEDFRGKGRTVQDGP
                     NYRWQFMIKYPDGISKEEGEKWFYDEVVPYFTNCCYVNRFVSSKIMINYGATAFDRVS
                     ELWFEGEEEWYKAVVEETKSFIKKPEWAQEEEFPYLKPQFNIASVFLGDIATMDAYSQ
                     YRGYIPMR"
     gene            57586..59673
                     /locus_tag="PC466_000616"
     CDS             57586..59673
                     /locus_tag="PC466_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDF2768039.1"
                     /translation="MVVDKEIVSILQILLNSTLITTNGLQEESNSSKRQITYRINKIN
                     DMLKVKNVPLICLRADKDIIVRKETKKAIKEILEKNYSKNTYYFSKTERLLYMYLMLF
                     INMEDISINHFINSIKVSRSTVNLDFKDLIPELEKKNIKVKNNRINGYYIVGNEMEIR
                     RVLIKNIIETLSNEKSSRVFDIFIKEYNLDSFEEAKKIILKLIKKYEITFVEDRLIEF
                     IYIFIFLKARMYSTRIVTQENVDIPNISVMSSMKEYKFAKELLEVYGSEDKIKPYNIM
                     YISAWILGISVGNYEEDTEDKDVISKIVNKMMTKFGYLSGVYYISQEKIFKQLYSHFR
                     PAYYRLLFKLPIYNPICEKVKEEYKLVYRIVSNAMKEFCGLFGEEIQEEELAYLTMHF
                     ATLFSNKKEFDGFRKRIALIVCSNGVGSSAILHAELTNLFPDLHFIPMSESVGLENIS
                     EPVDIVFTTNYNAEGLKTDVPVIKVSPVMTTKEKYKITREVYIQLGDIYLRQPKIDEV
                     MDIIKKYANVTSESILSSELLAYFTQIENFTSKEGEGPMLSEITNETLVKIKVKAKNW
                     EEAIRQSASVLVENNKVTEGYVDAMINSAKASGPYIVITKHVALPHARPEAGSKEIAI
                     GIATLDSPIEFGNNENDPVKYVFCLSAIDNNSHLRAMSELVELLEEDEFFKVLDSAKE
                     AKEIIDFIKTHEL"
     gene            59688..59975
                     /locus_tag="PC466_000617"
     CDS             59688..59975
                     /locus_tag="PC466_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2768040.1"
                     /translation="MYKILIACRAGVGSSLMLKIKTQQIIKENNFPIEVEHGSLDSLN
                     GFNGDAVETLIDVAEELKNKNLKFDIIGIHNIVDRNEIKTALEKFLASKEG"
     gene            60002..61273
                     /locus_tag="PC466_000618"
     CDS             60002..61273
                     /locus_tag="PC466_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HDF2768041.1"
                     /translation="MEFIISLLSTPAVLLGVVACIGLILQKKSAVEVFTGSSKTLIGF
                     LIFGIGASAMTGALQNFNKLFQHGFGITGVIASPEAATALAQGTYGFAVSCTLILGFI
                     LNLVFARITKFKNIFFTTGHSLFFSCVLVLIMKAHGFDNTITILIGGTILGFMSAALP
                     QFCQPFMRELTGGDEQAIGHFNMIGYGLSGYIGRLFSKHKDDTTETIEFPKWLSIFRD
                     FLMGLSIVMLILFYIATLKAGQAFTQEIAGSTHWLVFPLIEAFTFVAGMSILMSGVRM
                     FLAEITAAFVIISEKYIPGSRPALDVPTVFPYAPNAVIIGFISAYAAGLLAIAIMASF
                     PSIFPVVIIPAAHICFFSGGTAAIFGNTSGGWRGAIAGSFVVGLLLAFLPVILYPVYG
                     TLGIEGATFPNIDYNVVGSILHNILQFIKPI"
     gene            61331..61930
                     /locus_tag="PC466_000619"
     CDS             61331..61930
                     /locus_tag="PC466_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HDF2768042.1"
                     /translation="MENTLSEFLDNISNELSEFIASIDETSINKACELILEAEKNHGR
                     VHVTGIGKPGHVSGYISSLLSSTGTSAYILHGTEAVHGSSGQVVEGDVVIAISNSGET
                     QELKATLKTLKVNGAKIIGVSGNESSFLKNISDIFLFAGVKQEGDCLNKAPRASILAE
                     TIVLQSLSVVLQYAKGLNTQQYLKWHPAGSLGKSIREGI"
     gene            61935..62840
                     /gene="dapA"
                     /locus_tag="PC466_000620"
     CDS             61935..62840
                     /gene="dapA"
                     /locus_tag="PC466_000620"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HDF2768043.1"
                     /translation="MKYKGIICAMITPFDEKQNINSQATCKLIDYLIEKGIYGLFILG
                     TNGECHVLTDDEKVEFAKIVINHTNNRVPVFVGTGGNSTREVIDLSKRMEAIGASALS
                     IITPYFVTPTQQELILHYKTIANSVNLPIIMYNMPGKTGINIEPESVRELSKIKNIVG
                     IKDSSGKLDNMKAYIEVTQNENFSVFSGSDSLILDSLKAGSQGAVAATTNFLTEIGIS
                     IYENFMKGDLEEAQKAQSSIEELRRILKLGTIPSVMKKTIVLNGINVGTARLPVTEPT
                     GEVLEEIKRVVENYRTILNKSSENR"
     gene            62946..63578
                     /locus_tag="PC466_000621"
     CDS             62946..63578
                     /locus_tag="PC466_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketohydroxyglutarate aldolase"
                     /protein_id="HDF2768044.1"
                     /translation="MKKMNITKRMSECGALAIVREENLNRACEIAEGCIKGGITVIEM
                     SYTLNNAGEIIQGLNKKYGEILCVGAGTVLDSETARHAILHGAQFIIAPNYNEGVAKI
                     CNRYQIPYAPGCTSLTEAVDALSLGATFIKAFPISDFYGPKLVKVFKTPIPDMPVLAS
                     GGINLENLHIWLENGVDVCGFGGLLTKGTIEDITENAKKIREIIKNIREI"
     gene            63993..66164
                     /locus_tag="PC466_000622"
     CDS             63993..66164
                     /locus_tag="PC466_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HDF2768045.1"
                     /translation="MKKIIYVLFTIELLIVSLLGLNIVKDNEINNILYNDTTSISVMF
                     KDYKKLNKNYSKWIKDIADENNVAISKYVFNNNEKLSIYTTDTSLNNNIKLKSGKFPN
                     TNSNEFISNINTNNSNNSNQVGKFSTMSKDISILIRDFGKISEVGESGILYISTQNED
                     TINKILRELNVDRSIFVARLHDRYVNSNLYLNPSIIRDLILIILCFLATIIHYSISVS
                     REASILRLNGYSKLDIIARVIKNIFRIMILSSVTALLIYIIYILKLNIGVRACLYFAM
                     FSIICILINILISILIVGFNSRSSKYVLSLNGKKSYGFVNIMHFTLKIVFVSFLILSI
                     NNCILNYNMLQTQLGNLSEWDKAKNVYNLTLKDTGEQSLGKEEVIKNAKIKGFYKNLV
                     EEKDAFLIDSTNFEKLEDGSYMYEINSKGKNPEVSQYGKNIKINKNYLKVNPIYSNGK
                     EIFNLIDYDDKTINLLVPKKLQVHENEIKKEFRELFYFEKIEVENMYNKELNRELNKT
                     KKSDLNVNIIYVDNNQSYFTYNSLVMDDNRNLIDDPIAIIDIDNIDDSFYLSYISRCV
                     YFNSKKLDALADISNIIEAQGVEAHIQSLHAVYNEYGLEINKLEKYLNSEIFTIIIIA
                     ISNLMITYNIVASYYERNKYKLYIKKIFGYSTTARSMLLIVSLILTNIIPIGIISTRV
                     DLSNNIILFGLLILVIEVIVSIVLDKIISNSSFNKIIKGEH"
     gene            66169..66786
                     /locus_tag="PC466_000623"
     CDS             66169..66786
                     /locus_tag="PC466_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2768046.1"
                     /translation="MISLINISKKFKDKSIIDKFNLEISKGEFVAITGNSGSGKTTLL
                     NIMGLLEKPNSGDIIINNIKNPNSKQIRILQRDFYGYLFQNYALIENENVENNLKIAL
                     KYQKNINHNEKINYALESVGLRKYNKKKIYELSGGEQQRVALARVILKECEVIFADEP
                     TGNLDKKNRDIVFDILKNLNKNGKTIVFVTHDLELSEQADRVIKL"
     gene            66975..67319
                     /locus_tag="PC466_000624"
     CDS             66975..67319
                     /locus_tag="PC466_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HDF2768047.1"
                     /translation="MENLPNCPKCNSEYTYEDGTLLVCPECSHEWALGLGAEEDSNII
                     KDVNGNVLNDGDSVTVIRDLKVKGSSSSIKIGTKVKNIRLIHDSSDGHDIECKIDGFG
                     AMKLKSSVVKKA"
     gene            67889..68755
                     /locus_tag="PC466_000625"
     CDS             67889..68755
                     /locus_tag="PC466_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HDF2768048.1"
                     /translation="MIDIHKNIYDNKLFEELKIDCKKCFGLCCVALYFSASDGFPIDK
                     ESGKPCINLQPDFKCSVHNSLMKRGFKGCTAYDCFGSGQKVAQVTYKGIDWMQSPELT
                     NQMSEVFLIMRQLHEMLWYLKEASVLNISDTIKSKIDLIIEETEKITNMSPEQIINLD
                     IISHRTKVNLLLSQASESVMGKVKSFIKTSTLKNMKKLSKNIDLIGADLRKINLIGAD
                     LRGRFLIAANLRSTDLSGANLIGADLRDCDIRGANLENSIFLTQLQVNTAKGDSSTKL
                     PASLIRPKYWEK"
     gene            68868..69272
                     /locus_tag="PC466_000626"
     CDS             68868..69272
                     /locus_tag="PC466_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmaF family protein"
                     /protein_id="HDF2768049.1"
                     /translation="MSYQNYKCERDYVYDDYKYNKCNKCYNDYEEMTHVHEYSESVKL
                     AEECEDRHNHRAAGVTGEAIPINGGTNHVHKINDNVDFLDHFHKICVTTGPAIRIPGT
                     DKHIHLICGETTVNDGHCHKFLFTTQIEAPLV"
     gene            69450..69899
                     /locus_tag="PC466_000627"
     CDS             69450..69899
                     /locus_tag="PC466_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2768050.1"
                     /translation="MKSGIILEMKQINSTEYDEMLQVWESSVRATHDFLTEKDIESLI
                     PLVEIGLKEVENIVCIKDNDIIKGFIGIDKDKIEMLFIEDKYRGNGIGKKLIKYAIDK
                     YNVKYVDVNEQNKKAVGFYIHLGFKVFDRSEIDGQGNPFPILHMKLI"
     gene            complement(70055..70432)
                     /locus_tag="PC466_000628"
     CDS             complement(70055..70432)
                     /locus_tag="PC466_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDF2768051.1"
                     /translation="MLTPYLIFNGTCEKAFNFYAEAFGGGKTIFARLDSNPNNPIMHA
                     SVTFTKYEGCIMGADTDKPVVISGMAICVVLPSREAIEEISVKLAEGGTLVQEFLPHP
                     PPHQNDGAAEVLDRYGYTWYLST"
     gene            70694..71611
                     /locus_tag="PC466_000629"
     CDS             70694..71611
                     /locus_tag="PC466_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2268 domain-containing protein"
                     /protein_id="HDF2768052.1"
                     /translation="MVNMNIIEIRSDKIYKKIMDAPINKKEDIYRYELMKPFEFKWKC
                     MNVPIVARQKGGYDVIIASEMLGVLSPKDIDEKQKKNINVLSADKIWGTCKETIENSI
                     NAFIKEGYDLNIKDYKYSILLANPNSPYTILSDGYWGDGGIPGYIFLSLVPNEYTINR
                     LPVLIAHECNHNIRFQFIEWNNNITLEEMMINEGLAENFATWMFGEEMLGPWVSRTDI
                     ETLNTYIKPIIKSALKETGFQNITSYLYGDDIAKMQGYFPVGLPYCAGYACGYYMIKY
                     YLEKTNKSIIEATLLPYSEIIETVKEFWE"
     gene            72094..>72239
                     /locus_tag="PC466_000630"
     CDS             72094..>72239
                     /locus_tag="PC466_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium/proton antiporter"
                     /protein_id="HDF2768053.1"
                     /translation="MTELMIISGLVLLICITSSKVLYKFGVPILLIFILLGMLFGSDG
                     MVGI"
BASE COUNT        27527 a         8632 c        12007 g        24073 t
ORIGIN      
        1 atataaatta acctactgtt taattttcaa tgttcgtgtt tatttcttgt tccttttttc
       61 aaggacaagt aatactatac catctttaaa acagtaggtc aatacttttt ttatattttt
      121 ttataaattt ttttcatatt cttttttcag cttctctact acctttttct ctagtctaga
      181 aacagtcatc tgtgatatcc ctagttcttt agctatacta gattgtgttt tatcaaagaa
      241 aaatctatct ttaaaaattt taacttctaa ttcatttaaa gtttcaataa acttattaat
      301 aaaatcttca tactctatac ttccaaagtt accttcttct tttccaatct tatcaataag
      361 agttatatct ttatcctctg aatcatcatt acttgatgaa tccaaagaca ttggttgata
      421 tccataagaa gcctccatag cctctaaaac atcttcttca ctaacgccta tataatcagc
      481 tatatctttt acctttggat gcttcttatt ttcttgttct aatttaatct tcgcatcact
      541 tatctttttg cttaattcct gtattcttct tgggactcta agtgtccata ccttatctct
      601 aaaatacttt tttatttctc ctactatagt tggtgtcgca aagctggaga actcaaatcc
      661 tttctcaaca tcatatctat caatagcata aattaatgcc aatgaagcaa cttgatatat
      721 atcttcaaaa tcaacacctt tgtttatata cttcttagct aacaatcttg ctaaatacag
      781 atgtctttca ataagaatat ttctaatgtc tacattttta tttttattat ataaattaaa
      841 tagctctttt gtatccatat ttaggtaatg tgtagcatta gctacatttt tcattaaata
      901 tcaactccta aatatttagt catttttatt tttgtccctt gattatgttc tgattcaata
      961 tctacatcat ccattaaagt tttaattata aacaatccaa gaccactctc ttttggattc
     1021 tctaaatctg gtgtacttat tgagctaaca tcatatcctt ttccattatc ttgaatttct
     1081 atattaattg cattatctaa aatattaaat actatattaa acacatcatc tttactgtgt
     1141 tttattgcat ttgtacatgc ttcagatact gctaccttta tatcttctat atcatctatt
     1201 ggaaaaccca tcttattggc aattccagat gctgttaatc ttattatact aacataatct
     1261 ggatttgtag taatttccat ctttatagtc tcacaagcca aagtttatcc ctccacttta
     1321 aatattttat ctagacctgt tatagtaaaa atctttttta cgttactctt aggatttact
     1381 atgtatatct ctttttcatt tatttttaat ttttttaata cacctatcat agctcctaag
     1441 cctgttgagt ctatataatc taaatcttta agattaatct ttacatctaa catatttttt
     1501 tctattaaag catgtaaatg ttcctttagt ttatctgctg tagaaacatc aagttctcca
     1561 tcaagacaaa cattccaaaa tttattttgt gaatctaaat ttgaatcaat attcatagac
     1621 atgtaaaaac ctcctatttc cttttaataa ttttaaatat atttcctata ctcaatattt
     1681 tattaattac ataaactata tcatctattc cctttgatat tgatgatgca ttttcaacaa
     1741 tatcttgtat atgtctttca ttataatcta caatcttata tgccttttca acaaccttat
     1801 ttatgctgtt tagagtttta gctaaataaa ttgctactat aagagcagag cttcctacta
     1861 acactgctcc aatttgccac ccccatgcat tcattagtta acatctccct catcatcaaa
     1921 gcttttactt attactatat cttcttctga aatctttata tcttcttcat tattatcatc
     1981 gtccactaaa tttattattc tctctttaac atcattaaat gtttcatgta gaacttcttt
     2041 tggattttct ttgacatcat taaacttctc ttttgtttct tttcttagtt cagaaccttt
     2101 tttaggtgca aaaaacatac caaatataaa ccctaaaata gctcctaata ataaaaatcc
     2161 acctttttta caacttcttt tattgcacat aacaattact cctttcaatt ttaaattttt
     2221 atctaactac attatacaaa aagaatagga tatttatcct attcttcttc aatatttatt
     2281 ttggcaatcg aaactacatt gacttcatca ttcgtcttca ttaatttaac accacttgta
     2341 actcttccaa acagtgatat ttcattgact cttattctaa taagaactcc atcagaattt
     2401 ataatcatta tctcatcatc ttcgttgacc atatctgcac ctacaattgt accagttttt
     2461 tcagatatat tataagtttt aattccttta ccagctctta tttgacttct atactcttct
     2521 atatttgttc tctttccaaa accattctta cttacaacta acacatctgt acctttactg
     2581 caaaggttca tagacacaac aaaatcttct ttacttaaag ttataccttt tacacccatt
     2641 gctgttctac ccatatatct tatatcattt tcatcaaatc ttatagacat accttcttta
     2701 gttactaaaa gtacttcttg ttttccatct gtaagttcta ctccaataag ctcatcatca
     2761 tctcttaaac ctatagcaat aagaccagat ttatttatat ttttgaactc ttctctctta
     2821 gtctttttaa caataccttt tttcgttgca agtaataaat attcattttc atcattacca
     2881 tcaataggta ttagagtagc aattttctca tctgctgaca attgaagtaa attcactata
     2941 gcagtacctt tagcctgtct cttaccttct ggtatttcat atgcatttaa tttaaatact
     3001 ctacctttat ttgtaaagaa taatagtcta ctatgagtag ttgtagttac caagtgcctt
     3061 acaaaatctt cttctctagt tgtaagtgct gaaatacctc ttccacccct tttttgactc
     3121 ttataagtat cagatggaag cctttttata tatccaaagt gagtaagagt tattgctatt
     3181 tcttcatcac ttataagatc tctcatatct atttcgcctt cagcatgtct tatttctgtt
     3241 cttctctcat cagagtaatt ttcttttatt attgtaattt cattctttat tacatttaaa
     3301 agtaatcttt catcagctaa aatttctttt aatctattta tcttcttgat taaatcttca
     3361 tattcagctt ctatcttatc tctttctaaa cctgtaagtc tttgaagtct catatctaat
     3421 atagcttgtg cttggatttc agttaatttg aatttttcta ttaaacctat cttagcttct
     3481 tgcccagtct ttgaagctct tatcaagctt ataacagcat ctatattatc taaagcaatc
     3541 tttaatcctt ctaaaatatg tgctcttgct tcagctttat ttagttcaaa tttagttctt
     3601 cttgtaacaa catcttcttg atgtttaata taatgatata atatttgttt aagatttaaa
     3661 actcttggct gaccatctac aagtgcaagc attattatac taaaagtatc ttccatttga
     3721 gaatgtttat acaaattatt taatactata ttagcattag catccctctt taattctata
     3781 acaattctca taccatttct attactttcg tctcttaggt ctgatatacc ttctattctc
     3841 ttttctttaa ctaactctgc tattctttca accagtttag ccttatttac ttgataaggt
     3901 atttctgtaa ctattatttg ctgttttcct tttggtagtt cttctataaa agctctagac
     3961 ctaactttaa cttttcctct tccagttctg tatgcttctg ctatactttc ttttcccatt
     4021 ataattgcag ctgtagggaa atctggtcct tgaacaaatt ttattaaatc atctacacta
     4081 cactctggat tatctatcaa atatacagtt gcatcaatta cttctgctaa attatgtgga
     4141 ggtattgaag ttgccatacc aacagctata ccatttgagc catttactaa taaattagga
     4201 tatctagctg gcaatactga aggctctttt aacgactcat caaagtttgg tttaaagtct
     4261 acagtttcct tttcaatatc tctcagtagt tctaatgata atttactcat tttagcttct
     4321 gtataacgca tagcagctgg tgaatcccca tcaacagaac caaagttacc atgaccatct
     4381 actaaaagtg ctctagttga aaaatcttgt gccattctta ccatagcata ataaacagca
     4441 atatctccat gaggatggta cttacctaaa acgtccccaa caatacgagc tgacttcctg
     4501 tatggtttat ctggagttaa atttaactca ctcattgaat ataatattct tctatgaact
     4561 ggctttaaac catctctaac atcaggaaga gcacgtccag ctataacact cattgaataa
     4621 tcaatatacg attttttcat ttcttccgct atttcaatag ggagtatttt gttattttct
     4681 tccatgtata ctaatcccct ctctctatat atctaaattt ctaacaaatc ttgcattttc
     4741 ttctataaat tcttttcttg gagcaacctt atcacccata agcattgaaa atacttcatc
     4801 tgcaattgca gcatcttcta cagtaacttg taataaagtt cttgtctcag gattcatagt
     4861 tgtttcccat aattgctctg cattcatctc tccaagacct ttgtaccttt gaagttcaac
     4921 accatttctt ccaatttcat ctaataagat atttaactct ttatctgagt aaacataatg
     4981 ttccttcttt tgctttgtca ctttatataa aggtggctgt gctgcataaa catacccctc
     5041 atctataaga ggtctcatat atctaaagaa gaatgttaat aataaagttc ttatatgggc
     5101 tccatctaca tcagcatcgg tcataattat aattttatga tacctagcct tatctatatc
     5161 aaaatcttct ccaataccac aaccataagc tgttatcata ttttttattt catctgaaga
     5221 tagtatccta tctagtcttg atttctcaac attaagtatt ttccctctta atggaagtat
     5281 agcttgacta tttctatctc taccttgttt agctgaacct cccgctgaat ccccttcgac
     5341 taagaatatt tcacttttag atggatcttt ttctgcacaa tctgcaagtt ttccaggtaa
     5401 agatgtactt tctaatacac tttttctcct tgttaattct cttgcttttt ttgcagcttc
     5461 tctagctctt tgtgctctta aagctttatc aactatgatt cttgctgttg atgggttttc
     5521 ttctaggaaa gaccccagtt catcaactgt tacactatca actatacctc tcataaagct
     5581 attacctagc tttgttttag tttgaccttc aaattgaggt tctggtaatt taactgatac
     5641 tactgctgta agaccttctc ttatgtcttc accaagtagg ttaacatcat tttcctttaa
     5701 aaatttattt ctcttagcat aatcatttac agttttagta agagctgctt taaatccact
     5761 taaatgagaa ccaccttcgt gtgtatttat attgtttgca aaagaatata tgttctctgt
     5821 ataaccatct gtatattgca tagctagttc aacaaaacaa tcatcaacct ttttatctat
     5881 ataaactatg tcatcatgta taccagttct agatttattt aaatacttaa tatattctac
     5941 caaaccacct gtatagtgaa attcttttct tttttcttgt ccttctcttt tatcttcaaa
     6001 tactattttt attcctttat tcaagaaaga aagttctcta agcctatact ccaatgtttc
     6061 atatttaaac tctatttcat caaatattgt ctcatctggc ataaattgaa tcattgttcc
     6121 tttatcttga gattctccaa ctacttcaag cttagatgtt ggtaatcctt tctcatatgt
     6181 ctgcttatat atctttccgt ttaaataaac ctctgctacc atccattttg acaatgcatt
     6241 aactacagaa acaccaactc catgaagacc tccagatact ttatatcctc cgcctccaaa
     6301 ctttcctcct gcatgaagat tagttaatac tgtttctaaa gttgatttac cagttttagg
     6361 atgtatttca acaggtatac ctcttccgtt atcttttact aaaacactgc catcttcatt
     6421 aatagataca tatatgtctg aacaatatcc ttgtaaagcc tcatctatac tattatctac
     6481 aacttcataa actaagtgat gtaaacctct agggcttgta ctaccaatat acatacctgg
     6541 tctttttcta acggcttcta atccctctaa tacttgtatc tgacttgcac cgtattcttg
     6601 tttcatttaa tttcctccat tctctatgct aataacatcg ccattttcaa tattaaatat
     6661 tgtaacattt ttttcatcaa atattttttt atgtgaaact tcagcacttg ttataaacat
     6721 ttgaacattg cttaaattat ttactaaaag tttttgtctt gcttcatcta actcactaaa
     6781 aacatcatct aaaattaata ctggatattc ttcaacttca ttttttatta attctatctc
     6841 tgataacttt aatgatattg aagcagttct ttgttgacct tgtgaaccaa aaagtcttgc
     6901 atctaaatca tttatgaata tatttaagtc atctttgtgt ataccatatc tggtagtctt
     6961 agattctata tcattaggtc tattcgatga caacttggct aaaaatttat tatatactgt
     7021 atctatagta tcttcatcag ttatatttat ttgattttta tatcgaattg ataatctttc
     7081 aactccatta gtcaaattca tatgcatatt ttcagatata ttagctatct tttttataaa
     7141 gtctctacgc aaaatataaa tataacttcc atactttgct aacgtatcat catatacatc
     7201 taataaagct tcatcaacat gtatattttt aagcacccta ctcctttgag aaagtgtttt
     7261 attataattg gtaagatatt tataatattt aggtataatc tgactaatct ctttgtctat
     7321 aaatgccctt ctttctttag gaccctcttt aaccaacctt aaatcttcag gagaaaatat
     7381 aacaacattt aagttgccaa gtagttcttg tatcttttgt aaaggaactt tatttattct
     7441 tatccccttt ttatcttttc caataattag ctctattaga ctatatttat tatattttga
     7501 aaaacttcct ccaatgtata agttttcact attaaatcta accatttctt tatctttgtt
     7561 agtcctaaat gattttccaa aagaaagcat ataaatagat tctactatat ttgtctttcc
     7621 ttgaccattt ttaccaacaa gtagatttac tttcccatta aattccagat gcaacttttt
     7681 ataatttcta aaattaacaa gttgcaaact tttaagtttc acaaaaagtt ctcctttttt
     7741 tacaatactt ttattttagt tccttctatt ttaactatat ctcctgattt tatctttttt
     7801 cctcttctta attctatttc atcatttact gtcactaaac cttcttgaat taaaaatttt
     7861 gcatgacctc ctgttgatgc aatctctgct aatttaagaa attgatccaa ctttatatat
     7921 tctgattcta tagttatttc agtcataata gttcctcctt gtcactattt taaacaaatt
     7981 cctattgata cactaaaagt atattatacc ataaatatgc ttataaaagg agttgtctaa
     8041 gattagaaaa attttctaca aaagacaact ccttcatgtc tgctatatat ttgatgatat
     8101 tcttactgga agcagtaagt aaatataatt aacatcatct gttggtttaa ttatacaagg
     8161 atttacattt gtagtaaatt ctataaatat ttcctcatta tctatatttt tcaaaccttc
     8221 gataaaatat ctagaattga aagctatatc taggtaatct ccatctaaat ctatttcaac
     8281 ttcttcatac acatttcctt tttctgtgtt agaagtaatt gccattactt tatctcttat
     8341 agataacttt ataagattat ttttttctga ttgagacaat aaagacgctc tctctatact
     8401 atttaaaagt tccttagtgt ttaatttaac tctgctgtta tgttctcttg gcaataattt
     8461 tttataatca ataaaatctc cttcaagcaa tcttgtaata attttcgtat cattaattat
     8521 aaaaatagca tttttttcgt taaacccaac tttaacatta tcctctccag aaagcaaact
     8581 atttacatct ataagtgtct ttccaggaat tatgactttt atattttcag ttaaactatc
     8641 aactgaacaa ctttttacag ctaatctata tccatcaatt gctactaaat ttaagtttct
     8701 atctacaatt tctaaaagtt ctcccattaa aacaggtttt gtttggtcct gtgagatagc
     8761 aaatacagtt tgtttaatca tattttttag aatttcttga ggtatgctat ataaatcttc
     8821 ttcatttaat tctggtaatt taggaaattc ttttgctgca taacctttaa ttttaaatct
     8881 tgaatttaca caatttatgt aaatattatt ttctgaatca gtttctatct caacaaagga
     8941 atctggtaat tttctaatta tatctccaaa tagccttgca tctacaacaa catcaccttt
     9001 ttctatgatt tctgcttgta cataagtttc tattcctatt tcagcatcat atccagtaag
     9061 ttttaattga ccttcttctg tagatataag tatacctttt aataattcta ttgttgtttt
     9121 tccattaata gctttttgag caattccaat tctatttgct aggatttttt gattacaaat
     9181 tattttcaat gtggataacc tcctctggct ttttatatat aaaaataagt taaaatcata
     9241 gtagtaatag tagtaggtgt tgttgataat gttaataagt atgtataaca ttataaatac
     9301 aaagatatta acatgtgtat aagatgttaa tatctttgtt attttagact tgataatttg
     9361 ttaataattt ttgttcaaaa aaagtattaa caggttattc aagagatata aacatacaat
     9421 tgtgtataaa ttatcccttc aaatctgata taattttgtc tattttagtc ttaatttctt
     9481 cactttcttc tatatcctta gatactttgt catgagcatg aattactgtt gtatggtctc
     9541 tacccccaaa ctcttcacct attttaggaa gggataaatc agtaagctcg cgcgttaaat
     9601 acatagctat ctgtcttgga taagctattg aacgtgttct ttttttagaa ttaaaatctt
     9661 ccatctttaa attgaataca gaagatactt tttcttttat tctaagaaca tttatttctt
     9721 catttttaga agttgttata atatctttta aagcttctgt agcaagatca aaagatatta
     9781 ccctattgct aagagaagaa taagcaacca ctctagttaa tgcaccttct agttccctta
     9841 tgtttgactt aatatttttt gctatatatg acataacctc atttggcaca tctatacgtt
     9901 ctagttgagc cttttttcta agtatagcaa ttcttgtctc aaagtcaggt gcttgaatat
     9961 cagttataag tcccatttca aatctcgatc ttagcctatc ttctagtgta ggtatgtctt
    10021 ttggcggtct atcactagat ataattattt gtttgtttgc ttcatgaaga gtattgaatg
    10081 tatggaaaaa ctcttcttga gttctttctt ttcctgctat aaattgaata tcgtcgatta
    10141 gtaatacatc tacgtttcta tatttattcc taaattcttc gtttttatcg tcttttatag
    10201 agtttataag ttcattagta aatttttctg aagaaacgta aactactttt gagtcttttt
    10261 tttgactaac aatatgatga cctatagcat gcattaggtg agtcttacct aatccaactc
    10321 ctccatacaa aaaaagtggg ttataagctt tagctggaga ttctgcaact gcaacgcatg
    10381 cagcatgtgc aaatctattg ctattaccaa taacgaatgt atcaaatgtg tattttggat
    10441 ttagattggg gtaaagaact ctataattta aatctgtgct atcagaattt aaatcagcaa
    10501 cctctttttc gctcaataca aatttaatat tatatttttt taatgacagt tgactaatag
    10561 catcttcaat taaatgtaaa tatctattct ctaagatatc tttattaaaa tcactaggag
    10621 ccagtaagat taaatcatta agatgtattt ttaatggtac gatgttttta aaaaaggtat
    10681 taaaacttac tgaagttaag tcacctttta ttaattgtag ggttttgtcc cataaagaaa
    10741 ctatatccat aatataaacc tccgaacaga ataattaata ttttccacaa agttattaac
    10801 agaaaagcaa aaatatatat aaattttaca gaataactaa atttatggat aatggtgttg
    10861 ataaattaat aatagtataa attattaaaa aaatatgaaa agatataaac aatatgtaga
    10921 taaagttata aataacataa acatacaata aatggtgatt ataactagag tattgtcagt
    10981 aatcttaaaa gttatacaca aaagtatcca caagctgtga ataatttcta ataagttgat
    11041 aacatttatg cacattatca acaagtatat ttataatatc aaaatatatg tcaaacttca
    11101 atgatttgta actaatttat ccacaatatt aactaattgt tgataaaaat ataaacatgt
    11161 taaaattact ttatttgtgt atataattga aaaaaataat ttagaataaa attaaataga
    11221 tttttgctag tattttcaat aaaaaaaata cataatatat atatggtaga ttttgtgata
    11281 taagcgtccc aaaaactcgt tgacaacagt agtaaaagta tttataatta tatgtgttat
    11341 gtttactttg agggtaaagt tattattttt ataaacggaa aataaaatct gaaaggcggt
    11401 gcaaaataat gagtaaaaga acttatcaac caaaaaagag acaaagaagt aaagaacatg
    11461 gtttcagaaa aagaatgaag acgtctaacg gaagaaacgt gttaaagaga agaagagcta
    11521 aaggaagaaa tagattaact cattaattac aaaagggccg ctgcaaaggt ggcctttttg
    11581 tgtaaataat tacaattcat agctgtgttt atggaggtta actatggact ttaataggac
    11641 taaagggttg aaaaaagact ctgattttag aaaagtatat aaacacggca aatcttttgc
    11701 aaacaaatat ttagtaatat atatacttaa aaataaatca gattatagta gagtaggtat
    11761 ttctgtttca aaaaaagtag gaaaagctat tactaggaat agagtaagaa gattaataaa
    11821 agaagcctac agattaaata ttgatgaaaa aattaagcct ggatatgata tagtatttat
    11881 agcaagggta tctagtaagg atgctacttt taaagacata gacaagtcta taaaaaattt
    11941 agttaaaaga acggatattt ctatttaatt gtatgctata aatatggagg ttaatgactt
    12001 tgaataaaat aatttatata ttaaaggaaa taagtaggta tttatcgaat ttatgtattt
    12061 atttagtgag attttatcaa aagtatatat ctcccttaaa gggacctacc tgtagatttt
    12121 atccaacttg ctcacaatat tcaatagagg cgtttaaaaa atatggattt gtaaaaggta
    12181 tgtatttaac gataagaaga cttttaaaat gtcatccttt tcatccagga ggttacgacc
    12241 ctctaaaata aaagagagta actattagga ggtataaaaa aattgaatat aataggaaat
    12301 ttcttaggat tgattcttaa ggtaatattt gaatttgtta atcattatgg tatttctata
    12361 atacttttta cgatacttgt aaagattatt ttattaccat taacaattaa gcagactaag
    12421 tcaacaaagg caatgcaaga tatacaacct cgtataaaag agatacaaga aaaatataaa
    12481 aataagccag aaaaacaaaa tgaagaaatt gttaagttat atggagaagc taaaattaat
    12541 ccactatctg gttgtttacc tttattaata cagtttccta tattaatagg attatttagc
    12601 gttttgagag aaccagttgc tcatggcgtt tttgcaaaca aagctgcatt tttagcagct
    12661 gacaatgggt ttttatggat aaaaagctta acatcaccag attatgtatt agcagtattt
    12721 tcaggagcaa gtgcatatgt catgcaaaaa gtaatgacac ccaaagatca gttacaaggc
    12781 tctatgaaag taatgacata tgtaatggca ggtatgtctt tctattgggg atttatattc
    12841 ccagcaggac ttacattgta ctggacagta agtaacttat tctcaatagc tcaatattac
    12901 ttaataatga atcctttaaa agctaaactg gctgctaact ctaaggagga aaaagttaat
    12961 gagaaaaagc ctaaaattaa taaaaagtaa gagtaaagag gaagctataa gtaaagctat
    13021 agcagagttg aatttaaaag cagaggatat agaagtagaa atacttgaaa atccaagtaa
    13081 agggttttta ggttttatag gtgctaaaga tggtacttat gaaatttttg ttatcgagag
    13141 ggaagtagat gtagctaaaa attttataga ggtaatgttg aaaaatgcaa atgttgatgc
    13201 caaagtcaat gtatctcaaa aagataattt aatcatggtt gatattgaag gcaaagaagc
    13261 tgcaagttta attggtagaa gaggggaaac tttagattct attcaatttt tgactggatt
    13321 agctcttaat aaaataaata aagattctca tacaagagta cttgtagata tagaaaatta
    13381 tagatcaaaa cgagaagaat ctttaataag atatgctaat aaagttgcta gagaagtagc
    13441 gaaaacaaga aaaactaaaa aattagatta tatgaatcca tatgagagaa gaataataca
    13501 ttcagctctt caaaatgaca aatatgtaat tacatatagt gaaggaaccg atccatatag
    13561 aagattagta attgagtgta aaagataaag tcaacctcct aaacattagg gggttttatt
    13621 ttttaatatt attaaatcat taatgattgg ttaaatgtaa acctatatgt aaaaaattat
    13681 gaattaagag gtgataaatt tgtttataga tgatacaatt gcagcaatag ctacagcacc
    13741 tggagaaggt ggtataggta tacttagaat aagtggagaa agagctttga aggttgcaga
    13801 agaaatcttt aaatctatgt cgggaaagag tattgaagaa tacaataaga gaacattaat
    13861 atatggaaat atattggata atgaaaatat aattgatgaa gttttattgg catatatgaa
    13921 aggaccaaac tcctatacag gagaagatgt tatagaaatt aattgtcatg gtggatttat
    13981 ttcggtaaag aagatattag aattaatact atcaaaagat gttagattag cagaggctgg
    14041 tgagtttact aaaagagcat tcttaaatgg aagaatagat ttatctcaag cagaggctgt
    14101 aattgatgtt ataaaagcca aaactgatat agctcatgaa gttgctcaaa atcaattaga
    14161 gggttcttta tcaaagaaga taagagaatt gagagataaa gtcactgaga tattagctca
    14221 tgtagaagtt gctatagatt atcctgagga agatattgag catataacat atcaaactct
    14281 taaagaaaaa actgatgaac ttaaaaaaga gattaaaaaa ttatatgata cagctgaaag
    14341 tggaaaaata cttagagaag gcttaaagac ggtaattgtt gggaaaccaa atgtaggtaa
    14401 atcttcacta cttaattcta ttttaggaga gaatagagca atagttactg atataccagg
    14461 aactactaga gatgttatag aagagtttgt aaacataaaa ggtatacctt taaaaattgt
    14521 tgacacagca ggtataaggg atactgatga tatcgttgaa aaaataggtg ttgaaaagtc
    14581 taaagaatca tttactagtg cagatttgat agtaatggtt ttagatgcat ctagaaagtt
    14641 gtcagaggaa gatatagaga tattagaaaa acttaaggat aaacaaacaa tagtgctgtt
    14701 aaataagaat gatttgaaac aagagattga agaagaaaaa atacttaaat atgtagaaaa
    14761 taatagtata ataaaaatat cagctttaca acaagaagga atagaagaat tgcaagataa
    14821 aatagagtct atggtatata aaggtagtat caaaaataat tctagtttag tagtaacaaa
    14881 ttcaagacat aaagatgcac ttagtaaagc atataaatct gcaacagatg ctttaattgc
    14941 tttggaacaa agtatgccat ttgactttgt agaagtcgat ttaaaaaata tatgggacta
    15001 tcttggatat attaatggtg atacagtaac agaggattta ctagataata tattccataa
    15061 tttctgtatt ggtaagtaat gtacaaaagt aaatttgttt ttattataga gatttttaaa
    15121 aaatttgaag tgtttctcat gaaacattaa ttttgaaaag aaaggaatta taaatgataa
    15181 agtttgaagc aggaaaatat gatgttatag tagtcggagc aggacatgct ggatgtgaag
    15241 ctgctttggc tactgcaaga atgggatata aaactttgat aataacaatg tctttggatt
    15301 ccatagcatt aatgccttgt aatccatcaa ttggagggac tggtaaaggt caattagtta
    15361 aagaaataga tgccttaggt ggtcagatgg gattaaatat agacaagaca tatatacaaa
    15421 gtagaatgtt aaatactgcc aaaggtccag cggtacactc tttaagagca caagcagata
    15481 aatttaaata tcatgaagaa atgaaaaaga cattagaaga tgaaccaaat cttgatatag
    15541 ctatggatga agttgtagaa atacttcatg aaggaaatgt tgtaatagga gttggaacta
    15601 aactaggatg ttcatttaaa tctaaagctg taatattggc cactggagtt tatctgaact
    15661 caaagatata tatgggtgaa gttgcatttt atgaaggtcc taatgcattg gggtatgcaa
    15721 aatatcttac agatagctta gttgagcttg gtcttagaat gagaagattt aagacgggaa
    15781 ctccagcaag agttcataga gatagtatag acttctctgt aatgtcttta caagagggcg
    15841 atgaaaaagt aactccattc tcatttatga atgaaaatat agaaaaaaaa caagaacctt
    15901 gttatttaac aagaactaca gaagaaactc aaaaagttat actggataat ttaaaaaggt
    15961 ctgctatgta tagtggagta atagaaagta ctggtccaag atactgtcct tctatagaag
    16021 ataaagtagt aagatttagt gataaaacct cacatcaatt atttatagaa ccagaagggt
    16081 taaatactaa agaaatgtat atacaaggaa tttcaactag tttacctttt gaagttcaat
    16141 tagatatgta caaaactata aagggacttg aaaattgtaa gataatgaga cctgcatatg
    16201 ctattgaata tgattgtgtt gacccaactc aactaaaaat aagtttggaa ataaagggtg
    16261 tcgagaactt atttagtgca gggcaattta atggaacttc tggatatgag gaagcagcag
    16321 ctcaagggct tatggctggt ataaatgcag ttagaaagat agaaggaaaa gagccgtttg
    16381 tattagaccg ttcagaagct tatataggtg tcttattaga tgaccttgtt actaaaggaa
    16441 ctaacgagcc ttacagaatg atgacatcaa gagcagaata tcgactatat ttaagacaag
    16501 ataatgcaga tatgagatta actcaaaaag gttatgatat aggattagtt aaaaaagata
    16561 gatatgaaag gttcctaaat aaaaaggctg ctgtagataa agaatttgaa agattaaaaa
    16621 atgaaagagt tacaccaaaa gaagtaaata gtttgttaga agaaaaagga gcaacaccaa
    16681 taaaggttgg aatatctcta tatgaatttt taaagagacc agaggttact tacgaattgc
    16741 ttgaagaatt agggaagggc gctggagaag atgtttcaag agaagttaaa gaacagtgtg
    16801 taataataac taaatatgaa ggttatatag agaaacaatt gaaacaaata gaccaattta
    16861 aaaaacttga gaataaaaag ctggatgaga aaataaatta ttcatctata gaaggtctta
    16921 gattagaggc tagacagaaa ttagatgata taaaacctat ttcaataggg caagcatctc
    16981 gtatatcggg tgtttctcca gctgatatat cagttttact tatataccta gaacaagtca
    17041 gaagaactag aggtggcaaa ggtgaataat atagaacttc tgaaaaacgg gattgaaggt
    17101 tttaatatag atacgaatga cagtatgtta gaaaaattta aaatctatag agagatatta
    17161 gttgaatgga ataaaaagat gaatcttact ggaatagaag atgaaaaaga agtgtatata
    17221 aaacattttt tagactctat ttcagctgta aagaatggat atataaaaaa tgggatgtct
    17281 ataatagatg ttggtacagg tgctggtttt cctggaatac cattgaaaat atgtttagat
    17341 agcttagaac ttactttgtt agattcgtta aataaaagaa taaacttttt agaggaagtt
    17401 agtagagtac tagagttaga taatattaca tttatacatg gaagagctga agattttggt
    17461 aaaaatgaag actatagaga aaaatatgat gttgctacgg caagagctgt tgctggatta
    17521 ccgattctta tggaattttg tgtaccattt gtaaaagttg gagggtattt tatttgctta
    17581 aaaggtccga atgctaattt agagctagaa gaatcacaaa aggctattga tgttttagga
    17641 ttggagtata ttgaaaaaat agatgtagag ttaccagagg tagatttaaa tcataatata
    17701 ttagttttta aaaaggtgat ggaaacacca gttaagtacc ctagaaaagc tggtagacca
    17761 gctaaaaatc ctattaagta atgaaaaaag taatgaaaaa attattattg gtaagcttaa
    17821 ttatttctta ggaaataatt aagcttaccg taaaaaaaca aaaataaagg aattattaaa
    17881 gtagatgcag aaataaattt gtatgtacat atagagaaca aaaataattt atatctaaaa
    17941 taagagaggt atgttatgga agataaaaga gttatggaga tacctataga agatgtagtt
    18001 ccaaatccat atcaaccaag aaaaatattt tcacaagttt cattggagga attgagcaat
    18061 tctataaagg tatatggtat aattcaacct ataacagtta gagcaaaaga tggcaaatat
    18121 gaactaattg caggagaaag aagattaaga gcagctaaat tagcagagct taaaaccata
    18181 ccagcaatta taaataatat gaatgatgaa tcttctgctg ttctagcgtt attagaaaat
    18241 ttgcaacgag aagacttaaa tttcattgaa gaagcaattg gttatgaaaa cttaataaaa
    18301 gaacatgctt ttactcaaca gcaattagca gaaaaattgg gcaaaaatca atctactgta
    18361 gcaaataagc ttagaatatt aaagcttcca aacgatataa aaatgaagct aatagagaat
    18421 aatttaacag aaagacatgc tagagcattt cttaaactac caagtgaaga tttaatgcaa
    18481 agtgtgttag acaaagtcat aaaaaatgaa ttgactgtta aaaaaacaga aaaattgata
    18541 caagatgtat tagaagaaac taaagttcaa gaagagcctg ataaaaaaca gaatataaag
    18601 ggtgctatga gtataagaat ttacataaat actataaagc aggcctttga tgctatatca
    18661 aatacaggaa ttgatgctaa gtataatgaa atagataagg gagattatat ggaagttgtt
    18721 gtgaaaatcc ctaaaaaata gagattactg cttaccagta atcttttttt gtaatataag
    18781 ccttgtaata taaattgatt tatagacatt atttatactt aaaaaacacc tattcaacat
    18841 ttaaaattaa tttaattctt aaagggggga acatcatggg caaagttata gctgtattca
    18901 atcaaaaggg tggagtcggg aaaactacaa caaatgtaaa tttaagtgct agcttaggaa
    18961 ctttgggaaa gaaaatatta gtattagatt tagacccaca aggaaataca actagtggat
    19021 atggtattaa taaaaacgaa gtagaaaata caatctatga aattatgtta gatgggttac
    19081 atattaaaga agcaataata agtactgaat ttgagaatgt agatgtagtt ccatcagcta
    19141 ctgaactatc aggtgcagag atagagctta catctaaaac taatagagag tatattttaa
    19201 aaaattccat aaaagcggta atagatgaat atgattatat atttttagat tgtccaccct
    19261 cactggggat gcttacaata aattgtttaa ctgctgtaga tagtgtttta attccaatac
    19321 aatgtgaata ttatgcttta gaaggtgtta gtcaattaat ggagactata aaattagtaa
    19381 aatcaagatt aaatgctgat atagaaattc aaggtgttgt tttaagtatg tttgatggaa
    19441 gagctaattt atcaatacaa gtagttgaag aagttaagaa atactttaaa ggtagtgtat
    19501 atacaacttt aattccaaga aatgtaagac ttgcagaagc tccaagtcat ggaaaacctg
    19561 taatttatta tgataaaaga tgtagagggt ctgtagctta tttggagcta gcagaagaat
    19621 ttatagattt agaagaggag gaatggtagt atggagaata agtctaaaag aagtaataga
    19681 ttaggtagag gtcttagtgc attgatacca gaaattaaag gagaaacttc agaaaaagaa
    19741 atagtcaaca tagatataga caaaatatat ccaaacgaag ttcaacctag aaagcaattt
    19801 gatgaagaaa agataaaagt attgtcggac tctataaaaa attatggtgt tttacagcca
    19861 atagtggtta aaatggatga aaataataaa tatatgataa tagctggaga aagaagattt
    19921 agagcatcaa aacttgcaaa taaaaatcaa atacctgcta taattaaaga tatagatatg
    19981 aaagatataa tggagatagc cttaattgaa aacttacaga gggaagattt aaattcaata
    20041 gaagaggctc tagcatataa gagtttaata gagcattaca atgtaactca ggaagaaata
    20101 tcagaagctg ttgggaagag tagacctcat ataactaata cactaagact tttaaatctt
    20161 ggacaagatg ttatagaaat gatagacagt ggtagaatta cagcaggcca tggtaaggct
    20221 ttattgagaa ttgcagataa agatttgcaa cttcaaatag cgaaaaagat agaagaagaa
    20281 gaactttctg taagagaagt cgaaaatata gctaaaaaaa tatctgaaaa taaacaagaa
    20341 gaacctaaaa aatctaaacc taaggatgta tttattttag atgttgaaga taaacttaga
    20401 aatatatttg gaacaaaggt gaatatttct aaaggaaaga agaaaggtaa aatagagata
    20461 gaatactata atgatgatga tttaaatagt attgtatcaa tgcttcttga atagaacaaa
    20521 aatataaaac agagaggaag attgttatga tttatttaga taatgctgca actacatatc
    20581 caaaaccaga aagagtgtat aatgctgttt tagattgtat gaaaaattat tgtgcaaatc
    20641 caggtagagc aggccataaa cttgctatga gagctgctag ggagatatat gatacaagag
    20701 agaatatagc taagttgttc aatgtaagta atcctatgaa tatagtattt acatctaatg
    20761 caacagattc tttaaattta gcgataaaag gtgtattaca agaaggagac catgtaataa
    20821 caacgtctat ggagcataat tcagtaataa gacctataaa agcattggaa aaaaggggta
    20881 ttgaaaatac tgtagtaaaa tgcgattatg agggattttt agattatgaa gatttagaaa
    20941 aatcaataaa gagtaatact aaactgattg taacaacaca cgcatctaat gtatgtggaa
    21001 ctttaataga tataaaaaaa gttggagaaa tagctaaaaa acataatata ctatttttag
    21061 tagatgcatc acaaacagca ggtgtttatg atatagacgt aaatgaatgt aatatagata
    21121 tgttggcaat gccaggtcat aaatgcttat ttgggcctca aggaacaggt atattatatg
    21181 taagagaagg gttgaactta aatatattaa aagaaggtgg aacaggtagt aaatcagaag
    21241 aaatagttca accagagtta ttcccagata agtatgaatc aggaactcat aatactccag
    21301 gtatagcagg tcttaaccaa ggtatactat ttatatttga aagaggaatc aacaatataa
    21361 gacaacatga agaagaatta tgtcaatata tgatagacaa actagaggaa gtatcagata
    21421 taaagatata tggaccaaag gatagtaaaa aaagagcatc agtaatcgct ctaaatatag
    21481 gagatatgga ttctggagag gttactttct tattagatag tgattataat atagcaacta
    21541 gatcaggaat acattgttca ccactagcac ataccacttt aggtacttta aaacaaggtg
    21601 cagtaaggtt cagtatagga tatttcaaca caaaagatga gatagataaa gcagtggaag
    21661 ctttgaaaaa aatttcaaaa aataaatagc atgagattta ataatataga aataaaaaaa
    21721 ggggatattt caaaataaaa atttgaatca tctccttttt tgtacaaaaa agaaaagggg
    21781 ctcctaagaa cctctaatct atttgataat tgtttcaaga aattacttta agtaatctcc
    21841 ttcttcaaga actatatgac cactttcgta attagaacca tcaacagtaa tttttatttg
    21901 ttcaacattc atatttttta tgtaagtacg agcaactgaa tcaagcatta aagtttctgc
    21961 atcactacct aagtttgact ttgtaaagtc agagctaaca tctaatatac cagtttttac
    22021 accatcaatg tcttttgtag taaatgaatt taattttgca gattctggaa caactttaag
    22081 tttttgaagt tcttcaaata aagtgttctc atcaatttta tttaaatcaa ctttattttc
    22141 aattaaatct gtcttatcta catcaaaaga gtaaatagta gctgattgag ttttagtttc
    22201 ttcttttgga gtaggtttag ctttgttatt aggaacctct ttttcagtat tgttttcttc
    22261 ttttggttgt tcaacatttg tattgctctt agtttctttt ttagatgtat cacttccatt
    22321 ttgagcatta gtacaaccaa ctgcgaatat agatatagat aatatactta acactaacat
    22381 tattttctta tttttcataa aaatttctcc tctcttaaaa actattctta tatataatta
    22441 tagtcgttat gagcaaatat atgaatacaa aatagtaaca aatttaaaaa atgatttatt
    22501 taaattaata aaactcaaaa taaactaaat tttagtcatt tttatgggaa atcatttaat
    22561 gtacagtgaa aatattgtaa aataaaagta gtgtttttaa aataaatata agttataatt
    22621 atattataaa aaaatgtctt caaaaggtgg gaatagtatg gaaattttga gcttaggaga
    22681 aaagattaaa aaattaagaa aagaaaaaaa catgacatta aaagaattag ctggagatag
    22741 gataacagca gcacaaataa gccatataga gagggataaa tctcatacta gttatgaact
    22801 gttggaatat ctaggcgata agctagatgt aagtgtagaa tacttattag agaccaagga
    22861 aatgcaatca aaaaagataa ctgataattt aatactacag agcgaaattt atataaaaga
    22921 aaatgaatta aacaaggctg aggatcaaat aaaagaagtt ttagatatat gtaagagata
    22981 cgatttaatg gagaactatg gcagatgtaa ttttttaatg gctaatatta atttgaaaaa
    23041 atctaattat aatgatgcta tagaaaactt tgaaaaggca ttgtacttct ttataaaaaa
    23101 tagtgatagt gaaaatatac ttaagtgtta tttaaacata gggaaaatat atatgcagga
    23161 agacttttat aaaggtgcta taagccactt taattttgca gaggaaattt tgtcagagaa
    23221 taaatttgag gatgttaaca tacacaagga actatatagt aagatggcat attgttacat
    23281 aaaactagat aatccaaata tgtcattgaa gtacatagaa aagataaatg aaatagataa
    23341 tagaaatgat agaaaagaag atgtcgatat tttggtgtta aaagcaaata atatgcttga
    23401 gattggaaaa tatgaagaat caagagatta ctttaaaaaa gcactaaaaa tacttgagag
    23461 tgaggataat aaaactggat tagcaaatgt gtatttaaca atttgtgatg tttacagaaa
    23521 aataggtgaa acagatagag tacttgaata ttcacaaaag gtatatgaca taaagaaaaa
    23581 tgatgaagat gaatacatga tgtcaggatt atttaagata atagaagcat atatagataa
    23641 agaagattat gatttagcta gaaaatattg taagatagcc ttagcttcat caataaaaaa
    23701 taaaaataaa ttcaatgaat ataaagcatt gagattctat gctaatatgt ataaaaatca
    23761 gaatgaagta actcttgcaa ttgaatatct gattaaatgc ataaaaatag tatcagattt
    23821 aggcaacaat agaatattgg ccaatttata tatagactta ggtcaattat attcaaatat
    23881 atcaaaagaa aaagagttag aatattatca aaaaggtgta tttatgtaca aaaatttaga
    23941 aataatgtag ggtaaataaa cctataaggg tatagaaaca atctataaca agcaagataa
    24001 tatctatgat aaaatataaa ttgtatgaat atttttaagg agatgaatca gacaatgagt
    24061 ataaaaatag atgcgagagg gcttgcttgt cctaaaccag ttataaatac aaaaagagaa
    24121 ttggataacc tagaagaagg tgttgtagtt acaatagttg ataatgaaac agctaaggag
    24181 aatatattaa aacttgctaa atctttaagt tgtgaagcaa atattgttga cgaaaaagag
    24241 aattttatat ctatagaaat tagaaaaggt aaaaatatac tagataaaca aaatgttgta
    24301 gataataaag aaagtgaatt agacaataca tgtatattta tatcttcaga taagatggga
    24361 cttggaaatg acgaattagg aaaagtgtta ataaaaggat ttatatatac attaacagaa
    24421 tctaaacctt atcctaagta tgtactttta gttaatggag gagtaaaatt aagtgctgaa
    24481 aatgaagaaa ccatagaaaa tctaaaaata cttgagaata tgggtgtaga agttttatct
    24541 tgtggtactt gtttagatta ttataattta aaagacaaat tacaagtagg tacagttaca
    24601 aatatgtata ctatagttga gacattaaag aatgcatcaa ataccatttc tatataatgt
    24661 atgtttgttt aataatataa aactaataat aaagattaac tcaaatagat agtcagaaag
    24721 gattaagtaa tgaatcaaat gtatatagtg tcatttaatt cgacacatca tgcgataaga
    24781 tcagaaaagt tatttggtga aaatagtcta aaagtaatgg ctcttccaac accaagagaa
    24841 ataacagcaa gttgtggaat atcaattaaa ttttcttttg aagatatgga aaagataaaa
    24901 actattttgg ttgaaaataa tgtagatata aaaggaattt attgtataag taaattagaa
    24961 aatggttcaa aagaagtaga gaagttagat taggaggcta attatttatg ccaatggatt
    25021 taaaaatagg tgatattgtt gaattaaaaa agcaacatgc atgtgggtgt aaagagtttg
    25081 aaatcataag aacgggaatg gatataaaga taaaatgtac taaatgttca aggctaataa
    25141 tgcttgatag agagacctta gaaaagagag taaaaaagct aataaaaaag tgataaaaat
    25201 ttaacactta aaaaatgtca aataccgtat attaatatcc aaaattttgg tataataaga
    25261 attgaagaaa acattttcat gggggtgctt taattatggc agttaaatat gcaaaaagaa
    25321 tgcaaggatt acaaggatca gaaatacgtg agcttttaaa acttactcaa caaccacaaa
    25381 taatatcttt tgctggtgga atgccggctc cagagttatt tccagttgag gaaatgaaaa
    25441 aagtatcagt tgcagtgctt gaagaaaatg gaagatcagc tatgcaatat actacaacag
    25501 aaggatatga accattaaga gaaaaaatag cagctagaat gaatgataaa aacaaaacta
    25561 atgtaaacaa agatgatata ttagttacaa gtggttctca acaaggtcta gattttgcag
    25621 gaaaagtatt tattgatgag ggtgatgtaa ttttatgtga aagtccatct tacataggag
    25681 ctataaacgc atttaaatct tatcaaccta aattcataga tgttccaaca gattctgatg
    25741 gaatgataat ggaagaatta gaaaagatac tagaaacaac tgatagaata aaaatgattt
    25801 acgtaatacc tgacttccaa aatccaacag gaagaacttg gccacttgaa agacgtaaaa
    25861 aattcatgga aatagtaaat aaatttgaaa taccagtaat agaagataat ccatatggag
    25921 atttaagatt tgaaggagag actttaccat ctttaaaatc aatggataca aaaggattag
    25981 taatattctt aggaactttc tctaaaatat tctgcccagg atacagatta ggatggactt
    26041 gtgcttctcc agaaatttta tctaaattta actttgcaaa acaaggtgca gacttacaag
    26101 catcaactat atctcaaatg gaagtaagca aatttatgga tatgtatgac ctagatgcac
    26161 atgttgacaa aataaaagca gtttatgtta aacgtagaga tgtaatgctt aagactatgg
    26221 aagaagagtt cccagaagga ttagtattta ctcatccaga aggtggatta tttacatggg
    26281 tagagcttcc aagtaattta aatgctaaag aattaatgcc aaaatgttta gagaagaatg
    26341 ttgcttatgt tgctggagga ggattcttcc ctaatggtgg tagagaaaat actttcagac
    26401 ttaactattc aaatatgcca gaagaaaaaa taatagaagg tataaaaaat atagcagctg
    26461 tattaaaaga agctatgggt gtagaagctt aattaaaaat aataacttat atataataca
    26521 agggatggtt gttgccatcc cttgtttgtt tgaaaagtat ataattcacc ttatactaaa
    26581 ctttgtccaa aatttaaatt gacagaaata agaataaatg ataaaatgtg taggtatgag
    26641 attttagtct catttctctg ctctaagagt gtagagccgt taagtccaaa gggaggtgaa
    26701 ttatagtgag aaattatgaa ttagtttatg tggtaaagcc aaattctgat gaagaagtaa
    26761 gagaggctat actaaacaaa gttaaggaag ttgttgcaac tgacggagaa atagttaaag
    26821 ttgatacttg gggaactaaa aaattagctt atccaatagc taagtttaca gaaggtttct
    26881 atgtattagt taacttcaaa tcagcagtag acgttcctaa agagatagac agaaacttaa
    26941 agataaatga aaacgtaata agacacatga tagttgttgc ttaataactg gttttattat
    27001 aaaaaatagg tggtgttttt atgaatcaag ttgtattagt gggaaggttg actagagacc
    27061 ctgaattaag atacatccca ggtacaggaa caccagtggc atcctttaca atagccattg
    27121 atagagacta tgtaaaaaaa gatggatcta aagaaactga ttttatacct gttgaagtaa
    27181 tggggaaatc tgctgaattt tgtgctaact acataactaa aggtagatta gtagcacttc
    27241 aaggatctat aagagtagac aattatcaga cacaatcagg tgaaaagaga acttttacaa
    27301 aagtaagtac tagatcagta caagctttgg atagtaaaaa taaatcggaa aattcatata
    27361 gagagagtgc tccagctttt gagccaagct ttgaacctca aggtttagac ccacaaggtt
    27421 ttcaagctat agatgatgac gatataccat tttaaaaagg agggaaaaaa gtcatgatga
    27481 ataagaaaag acgtaagaaa aaaagagttt gtcaattttg tgctgacaaa aacgctaaaa
    27541 tagattacaa aagtactcaa agattacaaa agtatataac tgaaagagga aagatattac
    27601 caagaagaat atctggaact tgtgctaagc atcaaagaga attaacagtt gctataaaaa
    27661 gagcgagaaa tatagcactt ttaccatata cattagacta aaaaaatgag ccttgtgctc
    27721 attttttatt atatgtattt atatatctaa atgaggcgag ctataaagct cgtttttttg
    27781 tttatatact taaatatatt attatttatg atataatatt atatattaag gagggttgta
    27841 aacgtgaaaa tagataaagg ttctgagata acgagaaaca taaagataat agaatggatg
    27901 aaaacagaaa tattaatgag tgtaagtgat ttgtttaatt tattgtttaa aggggtaaaa
    27961 ccattagatg aagcaattca agatacttta gcaaatataa taatgataac atatctctta
    28021 gcaaagagat taggaattag ttttagagat gtggattata aagtcaagga aaaaataaaa
    28081 attggtatag atgaggacca tagcgttgaa agatggtatg gagatttatc taatttaaaa
    28141 aaacatatgg ataataggga gtgatattaa attgaataat aaaattagac tatctaaggc
    28201 aatgtctata atagttttag ctataataat cgctttagta atagcctata ttccaatgct
    28261 aggaatattt agtatgttag cagctgttcc atatgtaatt ataggtgcta ttactgatag
    28321 aaagtattct cttatatcta ttttggttac attttgtgta ctgattctat ttgcagacat
    28381 ttcttatgca ttaaatatat gtataatgta ttctttacca ggtatagtaa taggaaagat
    28441 gctaaagaga agctttgaac aagaggacag taataaattc gaaccgatat atggtggaac
    28501 cataatattt gtactttcaa tgcttgtata tttttttgta ttaaagacat ttttaaatgt
    28561 gaatctatta gatgaagttt ctaagatgat atcagaaatt gtaaatattc aaaaaaatag
    28621 tttttctgca actgaactta aagtgtttga taaaatgaag ccagatgaga ttgtaagtta
    28681 ttttacaaat atgctaccaa tgatgttatt tttacaaggg ttgttatcag cgtttgtcac
    28741 atattatttg agtgtatttt ttataaaaag gattacaaag atgaatataa gatttcctaa
    28801 atttgctgat ttttatttac caggaaatgc tatactcaca actttcttac tttatttatt
    28861 agtcttattt attcaaatta ttggttcaaa attatataca gaattaataa tgactaattt
    28921 acagctagtt tttaatttaa tgtttgtaat tcaaggtata gcagtttgca tttatttctt
    28981 aaagaaatgg ataagacagg gaccaaataa aattatgttt ttttcaggga taattttatg
    29041 tttatttgga tttatgggaa tatcttttgt tggtatggta gatagtataa ttgactttag
    29101 aaaggtaaga agctataaat ccacttagga ggatagaaat gagtaacaaa caaaccttta
    29161 aattaaatat gccagaaata aatttatata taattgttat tggtatttct agtataattt
    29221 tgctttatta caacttgtat gtagggtgtt tatttttctg tatttttgta tatatggttt
    29281 ttcacaattg gagaactact aatattagac gtcatgaatg gacagagtat attcaaaatt
    29341 tatctttaga tatagatgaa acaactaaaa aagccataat aaatcttcca ataccattat
    29401 gtattttaga atttgatgga aatatatcct ggtataatgg aaagttttat gatatgattg
    29461 gtcaaaaaga tttacttgat aaaaatatag aggatatagt taaaaatctt aatttaagaa
    29521 aagtattaaa tgaaaataaa gagatgtaca cagaaataaa ctataaagaa aaagaatata
    29581 caataattta taatgttata aaaaatgatc aagaaaaaaa tcctaaatat ttgatgatat
    29641 tatactggat agacaagact gaatatttaa aagtaaaaca aaattatgat gatgaaaaaa
    29701 atgcaatgat gctaatacaa gtagatggat atgatgaagt attaaaaagt gcagcagaag
    29761 ataagagagc tttaattaat gttgaagtag agaaaatact ttctgcttta gaattaaatt
    29821 caaatggtgc attgagaaga acttcaaaag acaaattctt cttggtaatg cataaaaaag
    29881 agctaaaaaa attggaagct gagaagtttt ctattttaga tacaataaga catattgatt
    29941 atggaaataa tcttcctgtt actataagta taggaattgg tatagatgga gatacattaa
    30001 atgagaacct aaaacttgct acgggtgctc tcgatttagc acttggtaga ggtggtgatc
    30061 aggctgttgt aaaaacaaaa gataaatttg tgttttatgg aggaaaatct aaagctgtag
    30121 aaaagaaaac caaagtaaaa tccagattaa taggtcatgc tttaagagag gttatacaac
    30181 aaagtgacca agtttatata atggggcata aatatcctga tatggatgct atgggagcag
    30241 cagttggtgt ttatgatata tgtaaatcct gtaacaaaac tgcaaacata gttttacaat
    30301 ctgtaaatga atctatagaa atatttataa ataaaataaa tgaaaataat tactataaaa
    30361 agctgtttat tggaaaagag gaagctattg acaactgtac taaaaataca ttagttgtag
    30421 tagttgatac tcatagacca aattatactg aatgtgaaga actgttaaag ctatcagaga
    30481 aggtagtagt tatagaccat catagaagag gtgtggagtt tataaatgat gcagtgcttt
    30541 tattccatga gatatatgta tcctcaacgt gtgaaatggt tacagagtta gttcagtata
    30601 tggatgaaga tgtaacaata aataaactta cagctgaagg gcttttagca ggtataagtc
    30661 tagatactaa aaactttgca ttcaaaacag gtgttaggac ttttgaagct gcttcttacc
    30721 ttagaaaagt tggagcagat actatagagg taaagaaatt cttcaattct gatgtaaaag
    30781 atttcataat aaaagctgaa ataattcaaa gtactaaaat aattaataat agaatatgtt
    30841 tagcatattc aagtactgag atagatagta taaatgttat aatagctcaa actgctgatg
    30901 agttattaaa tatcaaagaa gtagaagctt cctttgtatt aggtgaaaaa gatgatacta
    30961 tatttataag tgcgaggtct ttagggcaaa taaatgtaca tgtacttatg gaaaaattag
    31021 gaggcggggg acacatagat atagctggag cacagttaaa aaatgtttct ctaaaagaag
    31081 cttataagat ggtaaataaa ataatagagg agtatttgga ggaggaagaa tagatgaaag
    31141 ttatattatt aaaagacgta aaaggaactg gtaaaaaggg agaaatgaaa gaagtaagtg
    31201 atggatatgc aagaaatttc ttatttccta aaaagatggc tgtgcaagca gatagtgtag
    31261 caataaaaga attaaatgaa aagaataaat ctaaagaaat aaaagcacaa aaagagtatg
    31321 aagaagcagt tttattaggt aagcaaatgg aagaaattaa tatagaaata tattcaaaag
    31381 caggagaagg tggaagatta tttggttcaa taacttctaa agaaattgct gagcaattaa
    31441 agaaacaaaa agacatagac gtagataaaa gaaaaatatt attagatgaa ccaataagat
    31501 ctttaggttc aactttcgta gaaataaaaa tacatcaaaa agtaactact aaaataagag
    31561 tggatgtaaa agaaaaacag taataactag aggtgattaa gatggaagat atgacgagaa
    31621 ttcctcctca tagtgtagaa tcagaacaat caatattggg ttctatactt ctagataaag
    31681 atgctataat aacggttaca gaaactataa agcctgatga tttctataaa gaggctcaca
    31741 aaataatata tgaatgtatg ataactttaa gtaataaagg tgagcctata gacttgataa
    31801 cattaacaga agaactaaga aaacaagggc atcttaatga tattggagga atcagttata
    31861 ttacaagtct ttctactata gtaccgacga cttcaaatgt aaaatactat gctgatatag
    31921 taaaagaaaa gtctgtactt agaaagctta taaaagcttc taatgaaata ataaatctag
    31981 gatatagtgg agcaactaag attgaagatg ttttagaaca agctgaaaag agtatatttg
    32041 atatatcaca ggagaaaact agtgatgatt ttaaatctat aaacttagtt ttgatggatg
    32101 cctatgatat gatagaaaaa ttatatacta acaagagtga tgtcactggt ataactactg
    32161 gttttaaaga tttaaacaaa aaaataaatg gtcttcaaag gactgattta atattaattg
    32221 cagctagacc agcaatgggt aaaactgcct tttctttaaa cttggttcaa aatgcagcct
    32281 taaaaggtga tgcctctgta gctgtattta gcttagagat gtctaaggaa caattagtac
    32341 aacgtatgtt atcttcacaa tctagtgtag aattaaaaaa aataaagact ggaacactta
    32401 atgataatga ttggcctaga attatagatg ctatggcagt attatcagat gccaaaatac
    32461 acatagatga tactcctggt ataaaaatat cagaactaag gtcaaagtgt agaaagttaa
    32521 aaatagaaaa aggactagat ttagtgctta ttgattatct tcaacttatg gaaggtgaag
    32581 gtaataatga aagcagacaa caagagatat ctaagatatc aaggtcacta aaaatattag
    32641 caaaagaatt aaactgtcct gtagttgcac tatctcagtt atcacgtgca ccagaacaaa
    32701 gagcagacca tagacctatg ttatctgatt taagagagtc tggagcaata gaacaggatg
    32761 cagatatagt tatgttctta tacagggacg aatattatca tgctgattct gagagtaaaa
    32821 atataggaga agtaataata gcaaaaaata gacacggtga aactggttct gtggaacttg
    32881 tttggcttgg tgaagttcaa agatttgggg ataagttgag agacctataa tctaacgaat
    32941 atccacagaa cgtcctttct ttctacagga aaaatgtgga tacatgtcac taaatatgtc
    33001 caaacattga aatttagcta aaaaactatc cacactatcc acagatagcc tgttgataag
    33061 tgtgaataag tagataaagc aagcttttgg cttgctttat ctgtgtataa atattaatta
    33121 ttaggaggaa taatatggaa aaaataagct taaaatatat atatcccaat ataattaaag
    33181 tacttgatga aataaactta tttagagtaa ttgacaataa tttaagagag tctattgttg
    33241 tttatgctaa taatgtggat aatcagtatc atataaacat gactaataca aactttggaa
    33301 acataattaa catatgtaaa ttagaaaaac ttttagatgt ggataaattt atggaaaaag
    33361 ttataaaata tgaaaaagaa ataatagaga aagaagagtt ttcaaaaata gaagaatata
    33421 tgttaaatat tggagaatac taaaaaagtt gaaaaaaata cgaatgtttg atagaataag
    33481 taagtaaagt gttcgagagt atataaaata tagaggtgaa ttacatgaaa acagttgcaa
    33541 ttgttggttc tcaatgggga gatgaaggta aaggtaaagt tatagattat cttgctactc
    33601 aagcagatgt agtagtaaga gggcaaggtg gaaataatgc aggacataca ttagttgtag
    33661 aaggtaaaaa atacgcatta catctaattc catctggagt tttaaatcca aatacagtga
    33721 atataatcgg aaatggaata gtgtttgacc ctaaaggatt tttagaagaa ttggaaatgt
    33781 ttaaaacgga taatataagt acagaaaata taaaaataag tgatagagca catgtcatat
    33841 tcccatatca taaagaacta gatgcattgt cagaagaagc cagaggcgat ttaaagatag
    33901 gtacaacaaa aaaaggtatt ggaccttgtt atatggataa aacagagaga tctggtatta
    33961 gaatatgtga cttaatggat aaagataaat ttgctataaa attaaaagct caaatagatg
    34021 ctaaaaataa aatagttaaa aatatatatg gaaaagaaga attatttgat tttgaaacta
    34081 tatataacga atatctagga tatgcagaac aaataagaaa atatgtggca gatacgtctg
    34141 ttattgtata tgatgcagta agagcaggta aaaaagtatt gtttgaagga gcacaaggga
    34201 ctttattaga tttagattta ggaacttatc catttgttac atcttctcat ccaacatctg
    34261 gtggatttgc aattggtgca ggtataggac caaatatgat aaaagacgtt gttggtatag
    34321 taaaagcata tactacaaga gttggagaag gaccgtttgt tacagagcaa ataaatgaaa
    34381 ctggagataa gataagagaa caaggacatg aatttggggt aactactggt agaccaagaa
    34441 gatgtgggtg gtttgatgca gttatagtta agtatgcagc tagagttaat ggattgacta
    34501 gtatttcatt tatgttactt gatgtattaa ctggatttga taagataaaa gtttgtacgt
    34561 cttataaaat gggcgataag ataataacgg atttcccagc ttcattagat gatttagcaa
    34621 aatgtgaacc tgtatatgaa gaattagatg gatggaatga agatataact caaatagata
    34681 actttgatga ccttccagaa aatgcaaaga aatatgtagc aaaaatagaa gaactagttg
    34741 gagtaagtgt agatatggtt tctgttggtc caaatagagc tcaaactata ataagaagaa
    34801 atatatttgc ttaatatttt atcaattaaa taatttaaaa tagttgaaga agagtatctc
    34861 aagataatgt ttatagttat tagagatgct cttttatatt tgacttacat tgatttttta
    34921 ttaagttaaa gctacttata catattctag ctgaaattaa agttgaattt atgtagatac
    34981 atataggttt tttaaaaaga attttgttga aaataaatgg ctaaagatga ttttaattat
    35041 attctaaaaa aagtaaaaaa aactattgac taaaaattgt atagacgcta taatataact
    35101 tgtgagtgaa agaaacgacg aaaaaagtcg aaaaaatgtg gtctattagc tcagtcggta
    35161 gagcacctga cttttaatca gggtgtcccg cgttcgagtc gcggatagat caccaaaata
    35221 tggctcgttg gtcaagaggt taagacaccg ccctttcacg gcggtaacag gggttcaatt
    35281 cccctacgag tcaccagtat gggactatag ctcagctggg agagcacctg ccttacaagc
    35341 agggggtcac aggttcgagc cctgttagtc ccaccaaatt ttgaattaga gataaatact
    35401 agattatatg ctggtgtggc tcaacggtag agcagctgac ttgtaatcag caggttgtag
    35461 gttcgattcc tatcaccagc tccacaaagt acataaattc aaattaatat aattttctat
    35521 gttacaggat acttttaagt atcttttttt aatttcattt ttattgtatt aaaaatgaaa
    35581 ttaaacatac aacaaaattt tgaattactt gcaatgtgat agttttaaat ataaaattta
    35641 gaatcattct agcatagtat tatgtaatat agcaaattta atttatagta tcaataaata
    35701 tagactacta agaatgtaaa tgatttgtta gattaagata cattagatat gtaaatagaa
    35761 aaataaaaaa tatgttttaa tttatgtggc ataagtttta aacagagaag caagtttgct
    35821 cttacctctc tatttaaaaa taaaaaaatg ttttttaagg gctattttat ttaaatcttt
    35881 cccatctcaa atcatctcca gtaaattcta aaatcctaaa cttatctaag attctagaga
    35941 gagttctttg agtgtaagta tttcctattt gagatggtgt taagttggtt gaaataatga
    36001 tttttttacc agcaacaagt cttgtattta caatattgaa gatttcccca ctagtaaaag
    36061 aattattaag ttcagttcca aggtcatcta ttattaataa atcacaatca aacaagtttt
    36121 tataattatc ttcacttatt tggttatttg tgtctcttct aaatttataa tcttcaagaa
    36181 tatctaaaat tctaaaagaa gtttgataga ttacaacatt tcctttatct aacaattcct
    36241 ttgcaataca attgcacata taggtctttc ctagtccagt agaaccataa aacagtagat
    36301 tttcactatt atccttctta aaatcatgaa caaaattttc gcagatactt aaattattta
    36361 gcatattttc tctaggagat atttccccat cagagccttt cttaggagaa aatatattca
    36421 agttaaaatt cgaaaaattt tcctgactta aaatcctatc taaattagac attttataag
    36481 cttcatttac aatttcttgt ttgaggcaag aacatttttc tccattaggt aaaaatcctt
    36541 tatctttaca agaaatacat tgaaacttta tttccaagta atcaagaggt atgttacttt
    36601 cagataaaag tttttctttc tttactttta aagactctat attctcttta gtcttcttta
    36661 caatttcatc tttagatttg ggatttaaaa gtactatctt agctaaactg agacctattt
    36721 tagaaatttc atcatctata gattttatct cagggattct attatatacc tcattttttc
    36781 tatgttctaa taagagttca ttatcatctc ttctcttagc atatttagca agtatttttc
    36841 ttattttatc ctcattcatt taatcaccta cttaaacttt tctttttgac tttttttaat
    36901 aatctcatcg agctcatcag aggtatactg agtgaatgtt tcgttgaaat tatgaaactt
    36961 agtttttttg taagtattgt tgttttgagt agtattaatc tgcttcttat taatattctc
    37021 cttaactata cgttcttcct ctttttgctt taaatcattt aaatttttta tatttttttc
    37081 attccaattt ttaattatac catttatata agatatactt gggtttgaaa tattcttaga
    37141 cttagaacat gcatttatta tcaaatctat atccatatta aatttatcaa accaggtgtc
    37201 cataagttct ttttctgatt ttgatggttg tcttgaaaat cccaattcat tgaaaatcgt
    37261 tttatataaa atatatcgtt cacttcttac caaaaagctt tcttcaacat cttttggcgt
    37321 atataaattt gaatcatacc aatttctaat aatgccttca atgtatttaa ctggctttga
    37381 tgtaccagtt ttatctttga cgtattcata tgcgcaaagt atcatatcgg ggctcatatt
    37441 gtatttattc attatatcca taatactcat cttttcactt gggtcgagat atcgcccaac
    37501 tattttattt atagaattaa acatttttct aatacttgga ttttcagaag tagatacaac
    37561 cttatctgta ttagatttta tagatgaatt attgcttaat atattctcaa tatagaaatt
    37621 ttttaaatct aaaaattcta ttgaataatt aaaattatca tattctccat tgtcatgtat
    37681 ttttataatc ttcttttctt cccagaattt ccaagcagat aacacatcag acaatggtat
    37741 atttaggttt ttggctattg aattattgtc gaacttagga ttagaagtaa tatcacatgc
    37801 ttgtctatat cctaaaagat aaacttttac gtataacccg tccgccattg gcataaatat
    37861 atctataaag atattgggaa tagtgatttc acctaaatct atttcattgc tttctttaaa
    37921 aaacatttta tcacctcaga ttaaattata tcatttttta tattatattt gtctgtaaac
    37981 aaataaaagg tcacaagatt agcatgtaaa tattttctaa aagtattcat tttgaaaagg
    38041 aggagatatt ttggttataa aattcaacca aaaagtaaga agaacattat cagtagcgat
    38101 tctatttatg gtattaataa taggttgctt tatagaaaag gatgacagtt tagaaacata
    38161 caaagaaaaa actaattcaa aaataaatca gtataatatg gatgttatat ttgatgatga
    38221 gactaagagg ttaatgtgca atcagaatgt tgactacata aataatacaa aatcaaacat
    38281 agataaaata tatttccata tatatccgaa tgctttttcc aagaaagatt ttgctccttt
    38341 tgaaaaaagt gaaatgacaa gggcttatcc taatggattt aacgaaggat atatagatat
    38401 aaagaatata ttaaataata atagtaaaat ggagtataaa attaaaggag acaaaaatga
    38461 catattagaa atagaattag ggaaagagtt aaaaccaaat gaaagaatgt cattagatat
    38521 aaaatataac gtaaaaatac caaattcaat tggaagattt ggatatggag aaaatactat
    38581 aaatgttact aattggtttc ctatagcttg tgtaaatgat gaaaggggat ggaatttaaa
    38641 gagttatgaa actattggcg acccatttta tagtgagact agcgattttc atgtgaaact
    38701 attgattcca aataaatata aaattgctca tacaggaaaa cttattgatg ataaacatga
    38761 taataagaaa atgctatatg aaatagaagc tgaaaacgtt agagattttg catttatact
    38821 aagtagtaaa tttgatgtaa acaaagtaga ttcaaaggga gtagctatca atacatataa
    38881 tttaaataaa aagctttcta aaaaagcaac tgaagtggca aaagattcaa taaatatatt
    38941 tagtgaatta tttggaaagt atccttacaa agaattttct gttgtagcaa gtgacttttt
    39001 tatagggggg atggaatacc ctatgcttgt tatgatagac caaagtttat ataatgaaaa
    39061 aaatgaattt ttactagaat atgttattgc ccatgagaca gcacatcaat ggtggtattc
    39121 tgctgttgga aatgatgaaa taagtgaacc ctggttagat gaagcactta ctgaatattc
    39181 tacaatagtt tattttgaac aaaagtatgg taaagatatg gcaaacaagc ttataaaaac
    39241 tatggagata cagacaaaaa gttatttgag tgaaaatata tttaagccag caaatgagta
    39301 taaaaattct actgaataca gcttgaatgt ttatacaaaa ggcgcaatag catttaatga
    39361 aataagaaaa gaagttggag ataaagtatt ctttgagact ttaaatgaat actataataa
    39421 atataagcat aaaaatgcta atggaagagc ttttgtggaa ctatggaata gtaaaggtgt
    39481 agatataaat aagattataa gtgaatgtaa gtaaatagtg aatgtaagta aattttgtgc
    39541 agagtattaa attttattta atactctgtt tttttggtat aatataattt ataaggcaga
    39601 aaaagaggtg aaggaatgct aaagtattgt tcagtaggga gtggtagtag tgggaattgc
    39661 cactatatag ggtataaaaa tactaatata ctagtagatg caggattaag tggcaagaga
    39721 ataactacag gtcttaaaga cattggtgta gatgcagata aattaaaagg aatatttata
    39781 acacatgagc atgttgacca tataaaagga gcaggtatat tatccagaaa gttcgatata
    39841 ccagtatttg ctaatataaa aacatggtgt tctatgaagg acaaattagg tgacatcaaa
    39901 gataaaaata tgaaagtatt tgaaaatgat aaaacctact cattaggtga tatcatagtg
    39961 agaccttttt caatagaaca tgatgcgtct gatccagttg gatataattt ttatacagag
    40021 agtgatgaaa aaatgtctat agctactgat ataggatgta taactcaaaa tataaaaaaa
    40081 catctatata aatctaaatt agtagtattg gaatcaaatt atgaccctaa tatgcttatg
    40141 atgggttcat atacatatgc tttaaagaaa agagtaatgt caagtactgg tcatttatcc
    40201 aatgaagatg cagctaattt ctgcgttgaa cttattaatg aaggtacaga atctatatta
    40261 ttagcacatt taagtaaaga aaataatttt cctgagttag catatgagac ttcaaaagga
    40321 gtattagcat caaatgatat agtagttgga caagatgtaa aactagatgt actatcacga
    40381 aatgatgttt ctaatgttta tgagatgaag tagaggtgaa taactttgct aaagagaaat
    40441 tttgaaaatg ttgaggataa taaaatttta tactctataa agcagggtat gattttagca
    40501 atacctgcta ttatgactgg ttcaacggct cttgtaattt tgaatcttcc aataaaggct
    40561 tatcaagaat atttatcagg cttgtttaat ggagaggtta caaatattct taactttata
    40621 aatgattcta ctttaggaat tatttcatta ataatattat taacaataag ctatagttat
    40681 ggaaaaatat atgggagcaa gtatacagta cttgttccta tagttgcaat gtgctctttt
    40741 ttagtatttt cacatggtaa tgagcttaat tcttatatag aaatatttaa gacaaagtgg
    40801 ttatttacat ctataattgt ttctatgaca tcttctgtat tgtttgtaaa acttacagaa
    40861 tcttttgtta caagtgtaaa gtttcataca gaaggggctg atgcagactt taatatggta
    40921 gtttcggcta tagttccttt cataatagta gtatttttgt tttctatttt tagagtgata
    40981 atgataagtc taattggcag ttcaaacttt caagatatat tttataattt attttcaaat
    41041 gtttttaata aaatgggaac aaaccttatg agtgctctgt tgtttatttt tttaatgcac
    41101 tttatgtggt tttttgggat tcatggtagt aatgtattag ataccgtcgc aaaaaattta
    41161 tttgaaaata gtatggcaat taacataaat ttagttaata ataatcaatt accaacagaa
    41221 atttttacta agaccttttt tgatacaatg gttttattgg gaggatgtgg ctctttacta
    41281 tgtttagtaa ttgcaatttt tcttagtgaa aaacgtataa atgtaagaaa gctagctaaa
    41341 attgcttcaa taccagctct ttttaatatc aatgagatgc tagttttcgg gataccaatt
    41401 gtttttaact atattatgtt tgtacctttt gtaattactc ctataatctt aaccattaca
    41461 agttatgtgg ctatgtctac aggtattgta ccatgtacag tttcagctgt agaatggacc
    41521 tcacctatat ttttaagtgg atatatgtct acaggttcaa taagaggtag tttgttgcaa
    41581 gtatttaatt tatgtgttgg tgttatgatt tatattccgt ttataaaaat gtcgcaaaat
    41641 agatatacat atatgtttaa gaataatata gaaaatttaa caaacttatt aaaaaggtat
    41701 gaattaacag gtgaacagcc taatcttcta aaccataatg gtaaaatagg ttcaatttca
    41761 aaaatgttgg catcagactt gaagtttgct atgaaaagag gagaaataga acttttttat
    41821 caaccacaag tcaattataa tggaaatgtt gtgggagcag agggattact tagatggaaa
    41881 cattcaatag gagggttcat ttatccacca ctagttataa ttttggctaa agaagaaggg
    41941 ttcttagatg agcttggaga gtatattatt aataaagcat gtattgattt aaagaagagt
    42001 gaaaagctat tgagaaatcc tgttaagttc tctgtaaata tatctccaga ccaacttgat
    42061 gaccctaagt taccggagca aataaaaaat atcattagta gtaatgatat aaatcctaat
    42121 atgttaggta tagaaataac agagcaaatt gcattatcag gttcacaaat aattattgaa
    42181 cgtatcaatg cgatacataa cttgggaata aagttaatta tggatgattt tgggatgggg
    42241 catagctctc ttatatatct tcaaaataat aactttgata tagttaaatt ggatggttca
    42301 ttagttaaag agatacttac aaataaaaga agtagtgaaa ttataatgac tattgtaaat
    42361 ctttcaaaaa atttagattt tgatatagtt gttgagtatg ttgaaaatat agaccaaagg
    42421 gataagttat atggtttagg atgtgaaata tatcaaggat attattatag caaagcaata
    42481 ccttttgaag agtttgtaga atatgcaaat caagaaaaag agatataatt ttataagagc
    42541 ttgtaaattc tagtaatgca tagatttgta ataaaattaa gtttaggaga aatatatgaa
    42601 tataagtata gtagtagtag gtaaaattaa agaaaaatat ttaaaattag gtattgatga
    42661 gttcaaaaaa aggctttcta agtattgtaa gttagaaatt atagagttgg atgatgaaaa
    42721 agctccagag aatttgagtg ttaaggaaat ggaaattata aaagacaaag aaggaaagaa
    42781 aattttaggg aagataaagc ataatagtta tgttatagtc ttggctattg atggtaaggg
    42841 tttatcctct gaagaacttg ctaagactat gagtgattta gcagttagag gtaatagtag
    42901 tctctgtttt ataataggag gttctttagg gctttctgat gaggttttag gaagggctga
    42961 ttataggtta tccttttcta agatgacttt tcctcatcag atgatgagat tgatattgtt
    43021 agaacagatt tatagggctt ataggataaa taatggagaa ccgtatcata aataaatgat
    43081 acggtttttg ctaatttgac acttaataat attaaaataa caaaaaagta ttgaaagtat
    43141 attgcattta aggtagaatt aaataaaata ttataacatt ataatgttta tatagttgtt
    43201 aataaaaatt tggaggaaaa tatatgataa aaataatgtt ggcctgttca gcaggaatgt
    43261 ctacaagttt attagttact aaaatggaaa gtgcagctaa agaaaatggt atagagtcgc
    43321 aaatttgggc aataccagaa tcaactatac aaaatgaaat agaaaaatgt gatgtattat
    43381 tactaggacc acaagttaga tatgtattac ctaaggctca agaaattgct aagccatata
    43441 atataccagt agaggttata aatatgatgc actatggaac agttaatgga gaagctgttt
    43501 taaatagagc gatagaactt aacaacacta agtaatataa attataatgt atttttaata
    43561 tataaattgg gagaatcaaa ggatggatga aaagattata gaaatatctt ttaatataat
    43621 aggttatgca ggtgaaggta aagggttagc ttttgaagca ataaaagagg ctaagaatgg
    43681 aaatatagaa aaagcaaaag aattattaaa agagtctaag gaagttataa ataaagcaca
    43741 tagatatcaa acagaattaa tacaaaacga agctagtgga aacaggactg aaataagtgt
    43801 catacttata catgcacagg accacctaat gaatggtatg aattttcaac agttagctga
    43861 agaaatcgtt gatttacatt tgaaattaca agataaataa aaattaaaga gaataaatta
    43921 agagagttct taaaagatac attatgtgta gcacactaat tgttagatta ttgattcaat
    43981 atttagtgag taatacatta ggattatttt gaggactctt tttatattta gtttaaagtt
    44041 aataaatatt tattattaat aatataagat tatatgttat aatattataa catataattt
    44101 aagaggtgaa tcatgttaag aaatcaacca ttatatatac aagttgtaga tatattaaag
    44161 caaaaaatat taaataacga atataaaatt gatgaaaata ttccaacaga aagagaatta
    44221 gagcaagaat ttggagtcag taaaattact attagaaaag ctattgagat attagaatca
    44281 gaagggtatg tagagaaaaa aagtggaaaa gggacaaaag taataagtaa tagtcttttt
    44341 aataagctat caaaagcaga gtctttttca agtatacttt tatctaaagg tcataagtta
    44401 tctaaaaaga ctatttcaat tgaaaaaata ataaatgata caaattcaca agtatttagt
    44461 atatttggag aaaaatgtag caagattact agaatgtatt acttagatag taagccatat
    44521 atatttttta ctcattatat tccttttgat gaaaatctaa ctgttgaaag ttttaataat
    44581 gaaagttctt tatatatgta cttatatagg agaaatataa atataactag atttgaagat
    44641 gaatttttta tagaagaatc agaactagag gtatcaaagg ctctaaatct agctaaagac
    44701 atattattag gaagaaaaag aaagacctat gatgagaatg ataatatagt tgagctatca
    44761 tttgcaagat ataatacaga agtacaaaac tacgtaatta aatacgaaat ataataagaa
    44821 tcctgagttt attgaaatga taatatgctc aggatttttg tttagttgta aaaacgaaaa
    44881 atattataac attataatgt ttacaaccaa acattataat gttataatat ttttaataaa
    44941 taagtgatat tatcaattac ataaaaatta gtttatgtta tgaaatcgtt attgcattat
    45001 aaataaagga taatatcaat aatacagggg gataactatg gaaaaattcg caagtttttt
    45061 agagcgcaag attatgcctg tagcagcgaa gataagtaat cagagacata tgagagctgt
    45121 aagagcaggt ataatagcaa cattaccact aacaatagtg gggtcatttt tcacaatatt
    45181 attaaacata cctattgatg cttatatgga ttttatagct ccatttaaag caacattaga
    45241 tataccattt agatatactg taggattttt atctctatat gctacttttg ggatagcatc
    45301 atcacttgct aaaagctacg atttagatac aacaggtgtt ggtatgcttg cagttatggc
    45361 atttttagtt tctacaatag ttccaactca agtagttgaa ccagtaggtg gagttataga
    45421 agctggtaga tggatggata tggcaaaact taattcgcca tcattatttg gagctatcgt
    45481 aacatcatta attacagttg aaatatatcg ttttatgaag gaaaagaata ttacaattaa
    45541 gatgccagca ggagttccag tagaggtttc aaattcattt actgcattat taccgacagc
    45601 agtaatttta atgttattct gggtaataag acatatttta ggatttgata taagtgttgc
    45661 actaagcgct atgttatcac ctttaaaagg attcttatca ggaaatagtt taggtggtgg
    45721 gctactgaca gtattcctaa taactttatt ctgggtactt gggatacatg gtccagctat
    45781 aatggggcca gtaataagac ctatatggga catgtctata gcagaaaata taactgcatt
    45841 cacagaagga gtatcagctc atgcaatgcc aaacatattt acagaacaat ttttacagtg
    45901 gtatgtatgg atagggggag caggggctac tcttgcatta gttgtaatgt ttatgttttc
    45961 taagtcacaa tatctaaaaa gtttaggtag attaggattt ttaccagggt tattcaacat
    46021 aaatgaacct ataatatttg gagcaccaat agttatgaat ccaatactag ggataccatt
    46081 tataattgga cctataataa tgacaattct atcatatgtt cttactatta caggggttat
    46141 acctatgatg gtagcaagat taccatttgc aatgccagca ccaatagcag cagtaatgag
    46201 tactaactgg agtatactag caggtatctt agtattaatc aactttgtga tatcatttgc
    46261 tgtttattat ccattcttca aagtttttga aaaacaacaa ttacaaagag aacaagaaga
    46321 aatgagtgaa aatttataaa aatacataga tatagaggtt ttgtactata taaaatatag
    46381 aaaaagctta taagttatta agggtgaagg taggaggaat gacctttgcc tttaatttta
    46441 tatattttaa ataatgtaat ttgaggagga gaaagatgga aagaagatta ggaatatcag
    46501 tatatccaga gcatagtaac atggaagatg ataaggcata tataaaaatg gtttcaaaat
    46561 acggatttaa aagaatattt atgtgcatgc tttcaattac aagacctaag gaagaagtta
    46621 aaaaacattt taaagagatt ataacctatg caagagaatt aggatttgaa gtaatccttg
    46681 atatagctcc aaacatattt gatatattac aaatatctta tgatgattta acattcttta
    46741 gtgagttaaa tgctagtgga ataaggcttg actatggata tgatggaagt aaagaagcta
    46801 tgatttcttt caatccatat gatttaaaag tggaactaaa tatgagtaat gatgtagcat
    46861 acttggataa tataattact tacaagccaa atgtaaataa tatatatggt tgtcacaatt
    46921 tttatcctca aaggggtaca ggcttgccat atgatttttt tgtaagatgc tcaaatagat
    46981 ttaaaaagta tggaataaga actgctgctt ttgtcaattc aaaatacgca acaatcggac
    47041 cttggaatat aaatgatgga ctgtgtacgc ttgaaatgca tagaaactta gatattgcta
    47101 cagcaactaa gcacttattc gcaacaggat tgattgatga tgtaattgta ggaaatgcat
    47161 atgcaagtga agatgaatta aaaagaatgt ctgaagtaaa tgaataccaa gttgtattta
    47221 atgtagtagc taaagaaaaa acttctgaag tagaaaagat aataatggta aatgagcaac
    47281 actttagaag aggagatata actaatcagg tagcaagatc tacagaagta agaaaaaaat
    47341 atgctaaaga aaatttccct aaacatgata ataagaacat ctttaaaaga ggagatgtag
    47401 tgattggtaa tgatgacttt ggaaagtata aaggggaatt acagttgata cttcaagatt
    47461 gtacagatga aagaaaaaat aaggtgggta gaataaagga agacgaaata atacttttag
    47521 actttattga accttggagt aaatttaaga ttattttaga gggagagtaa agtgaagata
    47581 gacatattaa taaaatgtgg aaaaacagta gataaaagta taattgatat agctatatta
    47641 gacgataaaa taatagaagt aaaaaatcat atagatgatt ctaagtatca ggcaaaacaa
    47701 attataaact tagatggaga gaaatttatt agtgcgggtt ggatagatat acatacacac
    47761 tgctacgaaa gactagacct ttataaggat tatccagatg aggttggaat aaaaagtgga
    47821 gttactactg tagtagatgc aggaacaaca ggagctttag atataggtga attttatgaa
    47881 gatactaaaa agtataagac caatgtatat gctttaataa atattgctaa gcagggaata
    47941 acatctcaag atgaactttc aaatatgatg aatattgatg aatatgaact taaaaatgca
    48001 gttagaaaat acaaagattt tgttgttgga atcaaagcta gaatgagtaa aagtgttgta
    48061 atttcaaatg atgttgaacc tttaaaagta gctaaaagaa taaaaaatga acttaatcta
    48121 cctatgatgg ttcactttgg gagttctcct ccaacgatag aggatatatt tgattatatg
    48181 gaaaaaggag atatattaac ccatatatat aatggaaagc caaatggaat acttagaggc
    48241 aatgaggtta aaaaggaaat catagaagct aaagaaagag gtataattct tgatgtaggt
    48301 catggaaccg aaagttttag tatggatatt gcaatgaaat ctaaggatgc aggaattttt
    48361 ccagacacta taagtacaga tatatatatt aaaaatagaa taaatggtcc agtgtataat
    48421 ctatctacaa caatggaaaa gtttatatat atgggctatt cacttgaaga tataatagat
    48481 aaagttacta aaaatgcagc agatgcaata agtttaaaaa ataaaggttt aataaaagaa
    48541 ggatatgatg ctgatttaac tatatttgat gtggttaatg aagaaaaaga acttcaagat
    48601 tctttgaata agtcagtaat cacaagtacg tctataaagc caagagcagt agtagtcaat
    48661 ggagaatatt taaatatagg caactctata gaagagaatg agtagaaggg agaaactatt
    48721 gtatgagtag tatatttgaa aaatactctg taagacgtgt tataaatgct tcaggcaaaa
    48781 tgactatact aggagtatca acagtagata aggaagttat tgaagcaata ggtgaagggt
    48841 gtaaaaattt ccttataata gaagaacttg taaataaaac aggtgaatat atagcaaatt
    48901 tattagggtg tgaaagtgca ctaatagttt ctagtgcatc tgctgggatt gcacagagtg
    48961 tgggagcaat gatagcaaaa gatgatatga gtctagttta caatgtaaat aatcctaaga
    49021 aacaagttaa aagggaaata ataattccaa aggggcataa tgttgattat ggagttccag
    49081 tagaagtaat gataagactt ggaggaggag aagttgttga ggccggctat gctaatatgt
    49141 gtaacaagga acatataata agagagataa atgaaaatac agcagcaatt atgtatatta
    49201 aatctcatca ttgtgttcaa aagagtatgc taagtgtatt agatgcagta caagttgcta
    49261 aagaatataa tttacctttg atagtagatg cagcagcaga agaagattta aatgtatatt
    49321 atgaattggg agcagaccta gtgatataca gtggtgctaa ggctatagaa ggtcctagct
    49381 cggggttagt aataggtaag aaaaaataca tagataatgt aaagcttcaa tcaaagggta
    49441 taggaagagc tatgaaaata ggaaaagaaa atattgtagg tctaacatgt gcaattgaga
    49501 gatatataag taatgataaa gtaactttaa aagaaatgga ggacaagcta aatccattta
    49561 tagacaagat aaatactata aagggagtga gtgctagtat aactagagat tcagcaggta
    49621 gagaaatact tcgtggagaa attaacttta atgaagatat aataaataag tcaacacaac
    49681 aaattataaa tgaacttaga agtggagaga tagctatata cactagagac tataaggcta
    49741 atgaaggcaa gattgagatt gatataagaa gtgtaactgg aagtgattta gataatattt
    49801 ataataggat aaaaaatata gtagaaagtt agagtgtaga gtaagtgaca ttataatgat
    49861 ttaataaatt gaattttacc aatggagggg ataaatatga attgtatacc acaatattat
    49921 aaaaatagag tttgtttaaa tgttcttgca ggaagcataa aaaatgctaa agaagtatat
    49981 gatgcctgtg atggacatgt actagtagga gtactatcaa agaattatag cactgtagaa
    50041 gcagctattg aagatatgaa aaaatactca aaggaaatag ataatgcaat atctgtgggt
    50101 cttggagctg gagacccaaa tcagtcaaat atggtatctc agatttctaa agaacttcag
    50161 ccacaacata taaatcaagt gtttacaggt gtcgctacat ctagagcatt gcttggtcaa
    50221 aatgatagta taataaatgg attagtttct ccaactggta aaccaggatt tgtaaaaata
    50281 tccacaggtc cattaagttc aaaagaaaaa gatggtatag ttcctataga aacagcaata
    50341 gctatgatga aagatatggg aggaagctca attaagtttt ttccaatggg agggcttaaa
    50401 acaaaggatg aatatataga agttgcaaaa gcttgtgcaa agcataattt ttatttagaa
    50461 ccaacagggg gtatagactt agataacttc aaagagatag ttcaaattgc acttgatgct
    50521 ggtgtagaaa aagttatacc tcatgtttat acatcaataa ttgataaaga aacaggtgat
    50581 acgaaagtgg aagatatagg agtactttat aaaataatga aagaattatt gggatagatt
    50641 tatgaatata ttagcttttg gtgaaataat gatgagactt tcagtacctg actacaagtt
    50701 cttaacacaa accaatgaac taaattatat aattacaggc acgggattaa atatattatc
    50761 tggacttaaa aactttggat acaataccta tatgttgaca aagttgccta ataataatgt
    50821 aggtaaagca tcaagtgcaa atataagaaa gcttggagta aaagatgact ttatcacata
    50881 tggagggaat catataggag tgtattttct tgaaaatggg tatggagaaa gaccttctga
    50941 agtgacttat ttgaataggt taaatagttc attttgtgag agtaaattac aagattatga
    51001 tattgataaa tgtttagaag aaatggatat agtccatatt tgtggtattg ctatgcaact
    51061 tacagattca gttaaaaaga ttgctttaga actagctaga aaatcttatg aaaaggggat
    51121 aaaagtattc tttgatttta attttagaca atcattaaat ccagaaagga cttatgatga
    51181 tttagtaaat gattataaga aaatactacc atattgtcat gggctgtttg ctagttatag
    51241 agatataaat aagatactta atatagatag tctaaatata aaatctagtt cagaattgat
    51301 taaaaaagag tatgatatag atattgtagc tggaactatg agaagatttg atgatatgaa
    51361 taatagattt ataaagggat atatatcaaa tgatgatggt tattttgaaa gtagggagta
    51421 taagttagaa atatatgaca gagttggtgc tggggatgga tatgtggcag gaattatata
    51481 ttcatatttg gaaaatatga agagtgaaga tatagttgag tttggggttg ctagttcggt
    51541 gttagctcat acaacttatg gggataattc tttagtaagc acaggtcatg tacttagact
    51601 gatgaacaat gaaaaaatag atatattgag ataatacatt tgtatataat aaaattttta
    51661 tcttttttag acacactttt gacttgctta tatttgttaa acagagttat ttttaacgat
    51721 tataaatatt aaattaaaag ttagataata aaatagtaga aaatagcatt aaccatataa
    51781 aaatggttaa tgctattttt atagttaata ttgattaatt ttatattata gaaatgaact
    51841 tttctaatgc tggatttgta ttttttttat tccatacaac cacaacttca attctatttt
    51901 ctacttcttt tataggtact attgcaatat cacgttctat cattgtatct gtaacacaaa
    51961 atgaaggtaa aatggatatt cccatgttag aagataccaa tgattcaata gtattaagat
    52021 tatttgaacg ttgtaccaca ttaggtacaa accccgcttc acgatatcta ttttgtatca
    52081 ttgacttttg tccatactca tcccctgttt cttttacaaa aataaattta tcatgttgta
    52141 attcaattaa atcgatagaa tcctcattgt aaagtggatg accaggaggt aaaagagcta
    52201 ccaaagaata tctttctaca gttttatatt caaaatcttt taatggttga ttttctggat
    52261 taataacaaa agcgaggtcc atagaattat tttttactaa gtttaaaagt tcggttattt
    52321 cattagtaca aatatccata gatatattag ggtatgtatt agaaaattct tttaagtatt
    52381 gttgaagttt gtttttttca tatcctatta aggttccaat gctcaaagtt ccaaaaaaac
    52441 catgtgcaaa ttgttgtgtt tttgcaatag catcattgat attttttatt atagtacgtg
    52501 cctcagataa aaaaactttt ccggctggtg ttagttcaac atgacgttta cttcttgtaa
    52561 atagagttac atttatttgt tcttctaaag cttttatttg ctgtgtaaca gcagtttgag
    52621 aaatataaaa tttttctgct gttttggtaa aacttagatt ttctgctaca gatataaaat
    52681 attctaattg tttagtattc aaataatcac ccctatttaa acttgattgt ttgtaaacct
    52741 tatttatcta taattaaagc ttattatagt ataagaaaat ttacttttaa agaatattag
    52801 aaaatatttg tataaaaata tatgttttaa gtatatcttt acattagatt ttataaattt
    52861 attaataaga ataacttata tattccaatg aaaacgatat tggatttaag taagtttgtc
    52921 tcataaaatg aaagtatatc aattgataat actttaaata agaagggaga aaaaatggaa
    52981 gataaatttt atgcaaaagg caacggaaat aacggatata ttaaaaatct tgaagtttgt
    53041 tcctttaata acttagatgg aacttgtgga atgtttcaaa tggctctgta caaaagagat
    53101 gaaaaatact atttatatgg atgctgtttt ggaggaaata aaaaaaatgg agtaatgatt
    53161 agcgatatta cagaccctta taatccacaa tttataaaac attttcaaat gttagaccct
    53221 aaagagtatc ctacaacaac aactccaaaa attcaaatag cagatgattt aatgatagta
    53281 gcaatgagtt gtggaagtgg accaggagca cttgttgacc aagctaaatt agcaaatatt
    53341 aagtgtgaag caggaattag aatatacagt ttaaaagaag accctttaaa tcctaagttt
    53401 ttaggatatt gggattgtgg cttaaagcat gtaatgggtg ttcatagatt catgtacaat
    53461 ggtggaagat atgtacattt atcaagtgat tgtgttggct ttgaaggtct gatttatagg
    53521 gtcatagata taataaatcc taataatcca gtggaaatag gtaaatggtg gagaccagac
    53581 caatatgcag atggatatcc aaatagaact tttgatgcag gagcacctca ttgcccagaa
    53641 tttatggata aaggatggct tcatggacct ccatttgtaa gagacggaaa agcatattgt
    53701 ggttatggag gagctggttt agttgtatta gatgttgaag atttaacaag accaagatgc
    53761 ttaggtgaat tgccatttat gcctgcattt tctagtagac ttgcaggtgc aagaactcat
    53821 acagcattac cattgccagg aagagattta gtcgttgttc aaaatgaggg agaaagattc
    53881 cagttcttta aaccagataa cattacagat gttcaagcta tgaataatat acatatggtt
    53941 gatgttagtg acccaacaaa accaacatta attgctcaat tcccatatcc tgaagttcca
    54001 aaagatttcc cttatcctaa ctttaatgtt gcaggattag gaaaagcagg gccatttggt
    54061 ccacataatc ttcatgaacc aatggataat aagccatggt tagagcaaag aggagataga
    54121 gtatattgct gttatttcca tgcagggcta agggtttatg atgtatcaga cccatattat
    54181 atcaaagagc tagcatattt tataccacca aatccaaata aaacaccaga agaatcttat
    54241 ttcccaggat tcccaggacc acgcttggca gtaacagaag atcttatcgt tgatgataga
    54301 ggctacatca tcatagatgc tttagatgat ggattctata tattaaaaat gaaagaagat
    54361 taaataaata ctaaagaggg agagttgaaa atgaaaatac taggtatttc ttttggaaca
    54421 aaaaatggaa ataatgacac aatgtgtaaa gttgcactta aaggtgccaa agaagcaggg
    54481 gctgaagtag aatttattca aatgtcatct attaacatta aacattgtac tggatgttgt
    54541 gcgtgcgtta aaactttatt atccgggaaa ggtagtatgt gtgtattaaa agatgatttt
    54601 gaatggttgc ttgacaaaat gaaagatgca gatggtatag tagtttcaga ccctattttt
    54661 gaagaagggg catcaggatt attccatact ataatggacc gttttggacc cagagcagat
    54721 agaggaaata acattatagg aacaaaagtt gcagaagcta taggaggaaa aattccagac
    54781 tcaagaatgc ttaatgataa agtaatatca tttatgggaa taggaggttc tgactggggt
    54841 acaagagttc aatgtgaaca tgctatgcta gctctcatac caatgtggaa agttatagat
    54901 aatgcttggt tcccatgggc aaaggaatta gtaatggatg atacaaggct tgttcaagtt
    54961 catcaaattg gtttaaatat agttgaagca gcaaaagatt ttgaaaaagc ttcatatcaa
    55021 ggagaagaag gtgtatgtcc acattgccac aatagattat tctaccttga gtcaggtact
    55081 aaaaaggcaa tttgtgctct atgtggtata gttggagagt tagatactat aagtggaaaa
    55141 actatattta gttttccaga agagcaatta ggtcatgctc atgatacttt accaggtaag
    55201 tttatacatg gtgatgatat taagaaaatg gaaggtcatt atgcagaagt tcgtaaaaca
    55261 caagaattta aagaaagaaa aacatcttat aattttatag agccattaac taaagaaaag
    55321 caagctggag tttcattagg ataataatta aaatactaag actctttttt aagggatgtt
    55381 agatgttata ggaggcttat tgtatgaatg aaaagccaag ttttaaacaa attgaaatta
    55441 ttttagcagt tatttttttg gtacttacat attacaagat tggattaact ccagcattta
    55501 ttgttatatt tataccatta tacttaagtt attttgcagt atctatgatt gtaaatcaaa
    55561 tagcaattaa gctattggag ataaggcaag ctagggaagc tactaattac aatataggaa
    55621 atggatagaa agaaaaaaga aatattaaca ctgtctatgg ggattgcttt actacctcct
    55681 ttatgggcag tattagcacc ttatatagga ataaaaactg gagctgtagc actaatctgt
    55741 gcaggattat atgtaactaa tggtaataaa caaaaagatg gattaaaaat aatgtttggt
    55801 ttttggtgtg gagatttatg ggcagtgtta gccattttaa ttatgggata tatgaatttc
    55861 aatcaaaacc tagaattatt tttaacactt agtatattag gtttttttgc agttgtaatt
    55921 gcatccttat ttgaaaaaat aattttccta ccatcatggc tttgtggttg ggctataggt
    55981 ctaactatta tgacaggtga aaatattatt aatttacaag atatttgtat tcaaattgct
    56041 gtagctatgg cagtaggagt atggtacgtg ggtgcaggtg tagatttgtt tacaatatat
    56101 attttgagta aagataagaa aaagggaaat tgaaagcatg tgaatatact ttgattatag
    56161 gagaatggct atgggttttg aatttaaaat aatgagaagt ttaatatatg taggacttgc
    56221 caaggaagaa tatagaccta agttaatgga ctggttatat cgtcaccata ttccagatag
    56281 tattagcact tttggaccat attgtactaa atatgccttt tatcaagcat atcctacacc
    56341 aaatgaaggt gagcgttttg gtgcacgtaa gatgcaacta acagaacatt attggcttgt
    56401 agatgaacat atgcctgaga tggcaaatag aattatgaca gaatatatgc ctatggatgt
    56461 tctacgttgg caagggtgta taccagatgt agaaaataaa agggttcatg aaaatgcaga
    56521 aagtggagat gcaggacgtg cagtaggtgg agataatgga tgcccaccat ttatatttgc
    56581 ttttgttcca ataaactggg aagaagactt tagaggaaaa ggacgtactg tacaagatgg
    56641 accaaactat cgttggcaat ttatgattaa gtatccagat ggtatctcta aagaagaagg
    56701 agaaaaatgg ttctatgatg aggtagtgcc atactttaca aactgttgct atgttaatcg
    56761 ttttgtcagt agtaaaataa tgattaatta tggagcaact gcttttgacc gtgtatcaga
    56821 actatggttt gaaggggaag aggaatggta taaagctgtg gttgaagaga caaagtcgtt
    56881 tattaaaaaa ccagaatggg cacaagaaga ggagttccca tatttaaaac cacaattcaa
    56941 tatcgcatca gtattcttag gtgatatagc aactatggat gcatactcac agtatcgtgg
    57001 atatatacca atgagataaa aattatagtt tgtgataagt agaggaagta cttactctta
    57061 ctgctagaag aagacttatt gtacacttaa aagaatgaaa tagataagtg tcaatttatt
    57121 atatgagaga aactttaact ttcttggttt aaaatattaa agtcataagg aacatttatt
    57181 attaaatact ttatttatat gaattaattg aagaaaaagg atattaaact acaagttaaa
    57241 aaataaattt aatatattag aattataaat aaggcacatt aattttattt taaattaatg
    57301 tgccttttat ttatggtaat ttatgcataa ttagtatcgc tttgattctt taaataaatt
    57361 ttttttggtt tctttacata aggaaccctt ttttatttat aaaatctata agtgtaatat
    57421 agtagctatt ttagataagt ttaatttttg tctcaatcta aaacaaaagt tatacttaaa
    57481 tgaaattgaa aacgataaaa ttctcaaata aaataagtat tgtggaggtg atgaaagaat
    57541 ccaatgataa tatgaagact aatcttaata agaaagtagg ggttaatggt agtggacaaa
    57601 gaaattgtat caattctcca gattttatta aatagcacat tgattacaac taatggatta
    57661 caagaggagt ctaattcatc aaagagacaa attacttata gaataaataa aatcaatgac
    57721 atgcttaaag taaaaaatgt accacttata tgtttaagag ctgataaaga tattatcgtt
    57781 agaaaagaaa caaaaaaagc aattaaagaa attttagaaa aaaactattc taagaatact
    57841 tattatttta gtaagacaga aagactttta tatatgtatt taatgctttt tattaacatg
    57901 gaggatattt caattaatca ttttataaat tctataaaag taagtaggtc tactgtaaat
    57961 cttgatttca aggatttgat accagagctt gaaaagaaga acattaaagt taagaacaat
    58021 cgtataaatg gatattacat agttggcaat gagatggaaa ttaggagagt gcttattaaa
    58081 aacattatag aaactttgtc taatgagaaa agttcaagag tatttgatat ttttattaaa
    58141 gaatataatt tagatagttt tgaagaggct aaaaaaatta tattaaagct aataaaaaaa
    58201 tatgaaatta cttttgttga agatagatta atagaattta tatatatatt tatctttcta
    58261 aaagcaagga tgtattcaac tagaatagtt actcaggaaa atgtagatat tcctaatatt
    58321 tcagttatga gttcaatgaa ggagtataaa tttgctaagg aattattaga agtatatggg
    58381 agtgaggata agataaagcc ttataatata atgtatatta gtgcttggat tttaggtata
    58441 tcggtaggaa attatgaaga agatacagaa gataaggatg taatttcaaa aattgtaaat
    58501 aaaatgatga caaagtttgg atatttaagc ggagtttact atataagcca agaaaaaata
    58561 tttaaacaat tatattctca ttttagacct gcctactata gacttttatt taaattacct
    58621 atctataatc cgatttgtga aaaagtaaaa gaagaatata aattagttta tagaattgta
    58681 agtaatgcaa tgaaagagtt ttgcggatta tttggagaag aaattcagga agaagagtta
    58741 gcatatctta caatgcactt tgcaacactt ttttcaaata aaaaagaatt tgatggtttt
    58801 agaaaaagaa tagcattaat agtttgttca aatggcgttg gtagttcagc tattttacat
    58861 gcagaactta caaacttatt tcctgactta cactttatac caatgtcgga atcagttgga
    58921 ttagaaaata taagtgaacc tgtagatatc gtatttacta ctaattataa cgcagagggt
    58981 ttaaaaacag atgtaccagt aattaaagta agccctgtta tgaccacaaa agaaaaatat
    59041 aagattacac gtgaagtgta tattcaatta ggtgatattt atttaagaca acctaaaata
    59101 gatgaggtta tggatataat aaaaaaatat gcaaatgtaa cctctgaaag tattctttca
    59161 agtgagctat tagcttattt tacacagata gagaatttta catctaagga aggagagggg
    59221 cctatgctaa gtgagattac taatgaaaca ctagtaaaaa taaaggtaaa agctaagaat
    59281 tgggaggaag ctattagaca gtcagcttct gtattagttg aaaataacaa agtaactgaa
    59341 gggtatgtag atgctatgat taactcagca aaagcatctg gaccatacat agtaattaca
    59401 aaacatgttg cacttccaca tgctagacca gaagctgggt caaaagagat tgcaataggc
    59461 attgctactt tagatagtcc tattgagttt gggaataacg aaaacgaccc tgtaaaatat
    59521 gtattttgtc taagtgcaat agacaataat agccatttac gtgctatgtc tgagctagtt
    59581 gaactattgg aagaagatga gttttttaag gttttagata gtgctaaaga ggctaaagaa
    59641 attattgatt ttataaaaac acacgaatta taaaggagga tttaattatg tataaaattt
    59701 taatcgcatg tagagcagga gttggctcaa gtttaatgtt aaaaataaag actcaacaaa
    59761 ttattaagga aaataacttt ccaattgaag tagaacatgg ttcattggat tcactaaatg
    59821 gattcaatgg agatgctgta gaaacattaa ttgatgttgc tgaagaatta aaaaataaaa
    59881 atttgaagtt tgatataatt gggattcaca atattgttga ccgtaatgaa ataaagacag
    59941 cactagaaaa attccttgct tcaaaagagg gataaattta atatgataag gaggaatatt
    60001 tatggagttt attattagtt tgctgagtac acctgctgtt ttgcttggcg tagttgcatg
    60061 tataggattg attcttcaaa agaaatcagc cgttgaagta tttacagggt cttcaaaaac
    60121 acttatcggt tttttgatat ttggtattgg tgcctctgct atgacaggag cacttcaaaa
    60181 tttcaataaa ctgttccaac atggctttgg aattactggt gttatagctt caccagaagc
    60241 agctacagca cttgcacaag gtacatatgg ttttgcagtt tcatgtacat taattcttgg
    60301 attcatatta aatttagtat ttgcacgtat tacaaagttt aagaatattt tctttacaac
    60361 aggtcatagt ttattctttt cttgtgtatt agttttaatc atgaaagcac atggatttga
    60421 taatacaatc actattttaa taggtggaac tatcttaggg tttatgtctg ctgcactacc
    60481 tcaattctgt caaccattta tgcgtgaatt aacaggtggc gacgaacaag ctattggtca
    60541 ctttaacatg attggttatg gtttatcagg ttatattggg cgtttatttt caaaacataa
    60601 agatgataca acagagacta tagaatttcc taagtggtta tcaatattca gagacttctt
    60661 aatgggtcta tccatagtta tgttaatctt attctatatt gcaacattaa aagctggtca
    60721 agcatttact caagaaattg ctggttcaac acattggttg gtttttccgc ttatagaggc
    60781 atttacattt gtggcaggta tgtcaatatt gatgtcaggt gttcgtatgt tcttagctga
    60841 aataactgca gcatttgtaa tcatttcaga aaagtatatt ccaggttcac gtcctgcgct
    60901 agatgttcca acagtatttc catatgcacc aaatgcagtt attattgggt ttatatcagc
    60961 atatgctgct ggtctattag caattgctat tatggcatca tttcctagta tatttcctgt
    61021 agtaattatt ccagctgctc acatatgttt cttctcagga ggtacagctg caatatttgg
    61081 caatacttca ggaggatgga gaggggctat tgctgggtca tttgttgttg ggttattact
    61141 tgcattttta ccagttatac tatatccagt ttatgggact cttggtatag aaggagcaac
    61201 tttccctaat attgattaca acgtagttgg ttcgatatta cataatattt tacaatttat
    61261 aaaacctatt taaactaaat tatataaaag tatagtcata gttactatga tttcaaggag
    61321 gatacatctt atggaaaata cattatctga atttttagat aatatatcta atgaattgtc
    61381 agaatttatt gcctcaatag atgagacatc tataaataaa gcatgcgaat taattcttga
    61441 agctgaaaaa aatcacggac gtgtacatgt gactggtatt ggtaaaccag gacatgtatc
    61501 aggatatatt tcatcattgc tttcatctac tggaacatca gcatatatat tgcatggtac
    61561 agaagcagta catgggtcaa gtggtcaagt agttgaagga gatgttgtta ttgcaatatc
    61621 aaatagtggt gaaactcaag agttaaaagc aactcttaag actctaaaag taaatggagc
    61681 aaaaataatt ggtgtaagtg gtaatgagag ttcattttta aaaaatattt ctgatatatt
    61741 cctgttcgca ggcgttaaac aggaaggaga ttgtcttaat aaagctcctc gtgcttcaat
    61801 tttagctgaa acaatagtat tacaatcatt aagtgttgta ttacaatatg ctaaaggtct
    61861 taatacacag cagtatttga aatggcatcc agcaggaagt cttggaaagt ctattagaga
    61921 gggaatataa ttttatgaaa tataaaggga ttatatgtgc aatgataaca ccatttgatg
    61981 aaaagcaaaa tattaattca caagcaacat gtaaattaat tgattatttg attgaaaagg
    62041 ggatttatgg attatttatt ttgggtacta atggtgaatg tcatgtgtta acagatgatg
    62101 aaaaagttga atttgcaaag attgttatta atcatacaaa taatcgtgta cctgtttttg
    62161 ttggaacagg tggtaattca actcgtgaag ttatagattt atccaagaga atggaagcga
    62221 ttggagcaag tgcattatct attattacac catactttgt tacaccaaca caacaggaat
    62281 taatcttaca ttacaaaact attgctaatt cagttaattt acctattata atgtataata
    62341 tgccaggtaa gactggaatt aatattgaac cagagtcagt acgtgaatta tcaaagataa
    62401 agaatattgt tggaattaag gatagtagtg gtaaacttga caacatgaaa gcttatattg
    62461 aagtaacgca gaatgagaat tttagtgtgt tttcaggctc agattcactt attctggata
    62521 gtctaaaagc tggtagtcaa ggagctgttg cagcaacaac aaacttcctc acagagattg
    62581 gtatttctat ctatgaaaac tttatgaaag gggatttgga agaagctcaa aaagctcaaa
    62641 gtagtataga agaacttcga cgtatactaa aacttggaac aattccatct gttatgaaga
    62701 aaactattgt cttgaatgga attaatgttg gaactgcacg acttcctgta actgaaccaa
    62761 ctggggaagt acttgaagaa attaaacgag tagttgaaaa ttataggaca atacttaata
    62821 aaagtagtga gaatagataa tataaatagg gaaattacac tggtatataa ttaatatata
    62881 tattataaaa catgactaaa attaatgaat aagtaaagtg gtttgatgag tatagaggtg
    62941 ataatatgaa aaagatgaat ataaccaaaa gaatgtcaga atgtggggct cttgcaattg
    63001 taagagaaga aaatcttaac cgtgcatgtg aaattgctga aggatgtata aaaggtggta
    63061 taacagttat agaaatgagt tataccctaa ataatgctgg agaaataatt caagggctta
    63121 ataaaaagta tggtgaaata ctttgtgtgg gagcaggaac agttttggat agtgaaacag
    63181 ctcgtcatgc tatattacat ggagctcaat ttattattgc accaaattac aatgaaggtg
    63241 tagcgaagat ttgcaataga tatcagattc cttatgctcc aggatgtaca tcattgactg
    63301 aggcagtaga tgcactaagt ttaggagcga cttttataaa agctttccca atatcagatt
    63361 tctatggacc taaactagta aaggtattta agacaccaat acctgatatg ccagttttag
    63421 caagtggagg aattaatctt gaaaacctac atatatggtt agaaaatgga gttgatgtat
    63481 gtggatttgg tggtttatta actaaaggaa ctattgagga tattactgaa aatgccaaaa
    63541 agattcgtga aatcattaaa aatataagag aaatttaaca tggaggatga attagttttc
    63601 tattgacgag atatccacac attaattcct aagttagaag aaatattttc tagttgaggt
    63661 aaagtttata ttgaacttaa attaaatttt gttttaaata agatattatt ttagttgatt
    63721 gctaaaaata ctagaatcta tattaatgaa ttatactaat tttgtaccac tattaaaata
    63781 ttgtttgcta aaaataaaaa ataaccttaa aacagttgat tataaaaaat taactgtttt
    63841 aaggttattt ttatctttgt gacgaaatag acacttgcca tttagaatgt gacaatatag
    63901 tagttgttta gaaaaggtac aaagcattat actttaacta aagtaaaata tattttgctt
    63961 ttagaataaa aacaattagg agggagctat aattgaaaaa gataatatat gtattattta
    64021 caattgaact attaatagta tctttattag gtctaaatat agttaaagat aatgaaatta
    64081 ataatatttt atataacgat acaacaagta tatctgtaat gtttaaagat tataaaaagt
    64141 taaataaaaa ttatagtaag tggattaaag atattgcaga tgaaaataat gtggctatat
    64201 caaagtatgt ttttaataat aatgaaaaat tatctatata tacgactgat acaagtttga
    64261 ataacaatat aaagttaaaa tcaggaaaat ttcctaatac taattcaaat gaatttatta
    64321 gtaatataaa cactaataat agtaataata gtaatcaagt aggtaaattc tcaactatga
    64381 gtaaagacat atcaatttta attagggatt ttggtaaaat aagtgaagtt ggagaatcag
    64441 gaatcttata tatttcaact caaaatgaag atacaataaa taaaatatta agagaactaa
    64501 atgtagacag aagtattttt gtagcaagat tacatgatag atatgttaac tcaaatttat
    64561 acttaaatcc ttcaataatt agagatttaa tactaattat cctttgtttc ttggctacaa
    64621 taatacatta ttcaattagt gtgagtagag aggcttctat tttaagatta aatggatact
    64681 ctaagctaga tataattgct agggttataa aaaatatatt tagaattatg attttatcat
    64741 ctgtcacagc attattaata tatataatct atattttaaa attaaatata ggtgttagag
    64801 catgcttata ctttgctatg ttttcgatta tatgtatttt gataaatatt ttgatatcta
    64861 tattaatagt tggttttaat agtagaagtt ctaaatatgt gctatctcta aatggaaaaa
    64921 aatcttatgg ttttgtaaat ataatgcatt tcacattgaa aattgtattt gtatcatttc
    64981 ttatattatc cataaataac tgtattttaa attataatat gctacaaact cagttaggaa
    65041 atctatctga gtgggataaa gcaaaaaatg tttataatct tactcttaaa gatacaggcg
    65101 aacaatcttt aggaaaggaa gaagtaatta aaaatgccaa gattaaaggt ttctataaaa
    65161 atttggtaga agaaaaagat gctttcttaa tagattcaac taattttgaa aaacttgaag
    65221 atggaagtta catgtatgaa ataaattcaa agggtaaaaa cccagaagta agtcaatatg
    65281 gtaaaaatat aaaaataaat aaaaactatc ttaaagttaa ccctatttac tcaaatggca
    65341 aagaaatatt taatctaatc gattatgacg ataagactat aaatttatta gttcctaaaa
    65401 agttacaagt acatgaaaat gagattaaaa aagagtttag agaattattt tattttgaaa
    65461 aaatagaagt agaaaatatg tacaataaag agttaaatag agagttaaat aaaacaaaga
    65521 agtcagattt aaatgttaat ataatatatg tagataataa tcaaagctat tttacttata
    65581 actcccttgt tatggatgac aataggaatc tcattgatga cccaatagca ataattgaca
    65641 tagataatat tgatgattct ttttatcttt cttatatatc tagatgtgta tattttaatt
    65701 ctaagaaatt agatgccctt gcagatataa gtaacattat tgaagctcaa ggtgtagaag
    65761 cgcatatcca aagtttacat gctgtttata atgagtatgg tttagaaata aataaactag
    65821 aaaaatattt gaatagtgaa atttttacta taataataat agcaatatca aacttaatga
    65881 ttacctacaa tatagtagct agctactatg aaagaaataa atataagtta tatattaaaa
    65941 aaatatttgg ttattcaact acagctagaa gtatgttgtt aatagtctca ttaatattaa
    66001 caaacattat tccaataggc attatatcaa caagagtaga tttaagtaat aatattatct
    66061 tatttggact tctgatatta gttatagaag taattgtatc tattgtatta gacaagatta
    66121 tctcaaatag ttcatttaat aaaattataa aaggagaaca ttaaaaagat gatttcatta
    66181 ataaatatat ctaaaaaatt taaagataaa tctataatag acaaatttaa cctagaaatt
    66241 tctaagggcg agtttgtagc gataacagga aatagtggtt caggtaagac aactttactt
    66301 aatataatgg gattattaga aaaacctaat tctggtgata ttataataaa taatataaaa
    66361 aatccaaata gtaaacagat aagaatttta caaagggatt tttatggcta tctatttcaa
    66421 aattatgctt taattgagaa tgaaaatgtt gaaaataact tgaaaattgc tttaaagtat
    66481 caaaaaaata tcaaccataa tgaaaaaata aattacgcac ttgagtctgt aggtcttaga
    66541 aaatacaata aaaaaaagat atacgaattg agtggaggag aacaacaaag ggtagcatta
    66601 gcaagagtaa tattaaaaga atgtgaagta atatttgcag atgaacctac aggtaattta
    66661 gataaaaaaa atagagacat agtatttgat atacttaaaa atctaaataa gaatggtaaa
    66721 actatcgtat ttgtaactca tgatttagag ttatcggagc aggcagatag agttataaaa
    66781 ttgtaataat atcaactata ataaatataa gaaagagatt acagctaaat caagtttaat
    66841 aataatacga atagaattta aacattaagt aaattagtag tttgtaaata taagtataat
    66901 atgatatcat aaaggctcaa aagaaatttt atataataag aaatttaaaa ataacaaatg
    66961 gaggacatat aaagatggaa aatttaccaa attgcccgaa atgtaattca gaatatactt
    67021 atgaagatgg aactctttta gtttgtccag aatgctctca tgagtgggca ttaggattgg
    67081 gagctgaaga agattcaaat attatcaaag atgtaaatgg aaatgtatta aatgatggag
    67141 attctgttac agtaattaga gaccttaaag taaaaggaag ttcatcatct ataaagattg
    67201 gaacaaaagt gaaaaatatc cgtttaatcc atgactcatc agatggacat gatatagaat
    67261 gtaagataga tggttttgga gctatgaagc taaagtcttc tgttgttaaa aaagcgtaat
    67321 attataaata agctgtagtg tttattgttt ttcagtacag tataaaacca taagaatcta
    67381 ttaagtaata aaagtttgtt tatttatctt tatattttct tatggtttta ttaaatataa
    67441 attttattga acaccaaaat attctctcct ctacaaataa gccaatctta tttaaattaa
    67501 tatactttgt actatttata ctgaaattgt gaatttaaat gctatgttat ttaggtttgt
    67561 atagttaatt tatatatttc tgattttata aattgtattt attattatat cttgattcta
    67621 aaatcattaa aaatttcaac ttctataaag atttacaatt tatcaaatac attatgagta
    67681 tataaacaat ttattattac agtgctacat ttaaaataag tcttagtata aaggtattgt
    67741 tacaagtata aagaaactta tgtatgctat tggaataaat aataccttaa attataatta
    67801 agaataagaa ctgttaaata agggacttga ttatcattta gttatagata atataatatt
    67861 aaaaataaag cttaagagga gaaaaaatat gatagatata cataaaaata tatatgataa
    67921 taagttattt gaggagctaa agattgattg taagaagtgt tttggacttt gttgtgtagc
    67981 tctttatttt tctgcttcag atggatttcc tatcgataag gaatcaggaa aaccctgtat
    68041 taatttacaa ccagatttta aatgttctgt acataatagt cttatgaagc gaggttttaa
    68101 agggtgtact gcatatgatt gttttggttc aggtcaaaaa gtagcacaag taacatataa
    68161 ggggatagac tggatgcaat caccagaatt aacaaatcaa atgtctgaag tgtttttaat
    68221 tatgagacaa ttacatgaaa tgttatggta tcttaaagaa gcatctgtat taaatatatc
    68281 agatacaatc aaatcaaaaa ttgatttgat aattgaagaa actgaaaaga taactaatat
    68341 gagcccagaa cagataatta atttggatat catatcacat agaacaaagg ttaatttatt
    68401 attatcacaa gcgagtgagt ctgtgatggg aaaggttaaa tcatttatca agacttctac
    68461 tcttaaaaat atgaaaaaat taagtaaaaa tatagattta ataggagcag accttagaaa
    68521 aataaatcta ataggagcag atttaagagg tagatttcta atagcagcaa atttaagaag
    68581 tacagatttg agtggggcaa atttaatagg agcagactta agagattgtg atattagagg
    68641 tgctaatctt gaaaatagta tatttttaac acaattgcaa gtaaatactg caaaaggaga
    68701 ttctagtacg aagttaccag cttcactaat acgccctaaa tactgggaga aataattaaa
    68761 ttaatacata attttacaaa atatgaactt ttttgacttt aattcatatt atacattaga
    68821 gattctttac aagaatttct taatataata tagggagaga tataaaaatg agttatcaaa
    68881 attataaatg tgaaagagat tatgtgtatg atgattataa atacaataag tgcaacaagt
    68941 gctataatga ttatgaggaa atgacacatg ttcatgaata ttcagaaagt gttaagttag
    69001 cagaagaatg tgaggataga cataaccacc gtgcagcagg ggttactggt gaagctatac
    69061 caataaatgg aggtacaaat catgttcata aaataaatga taatgtagat ttccttgacc
    69121 atttccataa gatatgtgtt acaacagggc cagcaattag aatacctgga actgataaac
    69181 acattcactt aatatgtgga gaaactactg ttaatgatgg tcattgtcat aaattccttt
    69241 ttactactca aatagaagca cctttagtat aaactgatat ggattattgt agtaaatttg
    69301 ctagattata gtatataata aatgttaaaa atatataata gataatattt aaacttaatt
    69361 aggactatga tacttaacct tcgtagtcct ttctaagttt tgtataaaaa agtgttatac
    69421 aattaaaagt gatataggga ggaaatttta tgaaatctgg aataattctt gaaatgaaac
    69481 aaataaattc aacagaatat gacgaaatgt tgcaagtctg ggaatcatca gtaagagcaa
    69541 cgcatgattt tttaacagaa aaagatattg aatctttgat accattagtt gaaattggac
    69601 ttaaagaagt agaaaatata gtttgtataa aagataatga tataataaag ggctttatag
    69661 gaatagataa agataaaatt gagatgctct ttatagaaga taaatataga ggaaatggta
    69721 ttggtaaaaa attaataaaa tatgctatag ataaatacaa tgtaaaatat gttgatgtaa
    69781 atgagcagaa taaaaaagct gtaggatttt atattcactt aggatttaaa gtgtttgata
    69841 ggtctgaaat agatggacaa ggtaacccat ttccaatact acatatgaaa ttaatttaaa
    69901 gttatacttc tcacttattc gcaaaaatat ttacttaaat ttttatacaa ataaaagtcg
    69961 tgacagtctt aggacacgac ttttttacta cactattaaa ttgaaattta tctgttctat
    70021 attatgatta ttagatgtag tttttttatt tttactatgt acttaaatac caagtatacc
    70081 catacctatc aagtacttca gcagcgccat cattttgatg tggtggtggg tgtggtaaaa
    70141 attcttgtac aagtgtacca ccctcggcaa gttttacaga tatttcttct atcgcttctc
    70201 gagatggtag aacaacacaa atcgccatgc cagaaattac aacaggcttg tctgtatccg
    70261 cacccattat acaaccttcg tattttgtga aagtaacact tgcgtgcata ataggattgt
    70321 ttggattgct gtctaatcgc gcaaatatag tttttcctcc tccgaaagcc tcagcataaa
    70381 aattaaatgc tttttcacaa gtaccattaa atattaaata tggagttagc atgaccaata
    70441 tatcctcctt gatatagaat aatttatagt tgcacctgat aatctaaatt atgatttagt
    70501 aaattgtatc atagggaaac cttgaagtat ataatttttt attattatat tatacaaatt
    70561 tattaattta aaaaaatgtt atatgtacgg aaggtttaca ggataaaata taataaaaag
    70621 attaaggtga cattataaaa aatgtatatt gacattgacg ctacgtaatt gtatatactt
    70681 tgtcttaaag gagatggtaa atatgaatat tatagaaatt cgctcagata aaatatacaa
    70741 gaagataatg gatgcaccaa taaacaaaaa agaagatata tacagatatg aattgatgaa
    70801 gccttttgaa tttaagtgga agtgtatgaa tgttccaata gttgctagac agaaaggtgg
    70861 atatgatgta attatagcaa gtgaaatgtt aggggtttta tcgcctaagg atattgatga
    70921 aaagcaaaaa aagaatataa atgtgttatc tgctgataaa atttggggca cttgcaaaga
    70981 aaccatagaa aactctataa atgcttttat aaaagaaggg tatgatttaa acattaagga
    71041 ctataaatat tcaatattat tggcgaatcc aaatagtcct tatacaatat taagtgatgg
    71101 atactggggt gatggtggga ttcctggata tatatttcta tcattggttc ctaatgaata
    71161 tactatcaat agattaccag tattaatagc acatgaatgt aatcacaata ttagatttca
    71221 gtttatagag tggaataata atataacatt agaagaaatg atgataaatg aaggtcttgc
    71281 agaaaatttt gcaacatgga tgtttggaga ggaaatgtta ggaccttggg tcagtagaac
    71341 agatatcgaa acattaaata cttatataaa gccaataata aaaagtgctt taaaagaaac
    71401 tggatttcaa aatataacat cttatcttta tggtgatgat atagctaaaa tgcaaggata
    71461 ttttccagta gggttgcctt attgtgcagg atatgcttgt ggatattata tgattaagta
    71521 ttatttagaa aagacaaata aatcaataat cgaagcgact ttattgcctt atagtgagat
    71581 aatcgaaaca gtaaaagagt tttgggaata aattttataa attgcataat ttgaaataaa
    71641 ttatgcaatt attttatttt taagaaaaaa taaattgaca ataatttata agaaatatac
    71701 aataatatat ataaagaaat atttcaatat ttaaaagttt taagatttca tatctagagt
    71761 acctaacatt acatgttagt ttcttgttac ttatctaatt actttatatt tcgtagttat
    71821 atataaaatt actataaaaa atgaaatata ttaaacaatc aactaaaaaa tgaaatatta
    71881 ataaaaaaaa ttcaaattat aaatattaaa tgaatataat taaaacaaat atataaattt
    71941 aagtataaca ctcacatttt aatgtattgt gaaatttttg ttgaacttta tgtaccataa
    72001 cttataaaat ttatgtcatg ttatatttga ataagtaata aaattgtaga tgcaaattaa
    72061 tctacaaaat ttatatgaaa tggagttgat gctatgacag aattaatgat tataagtggg
    72121 ttagtactat tgatttgtat aacttctagc aaggtattgt ataaatttgg agtaccaata
    72181 ttattgattt ttatcttact agggatgtta tttgggtctg atggaatggt aggaatcta
//
LOCUS       DAMJYN010000008        69543 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.008, whole genome shotgun sequence.
ACCESSION   DAMJYN010000008 DAMJYN010000000
VERSION     DAMJYN010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 69543)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 69543)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..69543
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.008"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            68..412
                     /locus_tag="PC466_000631"
     CDS             68..412
                     /locus_tag="PC466_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HDF2768054.1"
                     /translation="MEIKRYEGTGRMSRAVVHNNTVYLCGQTHAEGGVIEQTTEVLAK
                     IEDLLNKYGSDKQHLLSVTIYLRDMKDFEAMNSVWDAWVEKGFEPARACVEARLAREH
                     LLVEMSVVAATK"
     gene            complement(571..2667)
                     /locus_tag="PC466_000632"
     CDS             complement(571..2667)
                     /locus_tag="PC466_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CocE/NonD family hydrolase"
                     /protein_id="HDF2768055.1"
                     /translation="MIKFKLYISGLYSGNVIFDGDLLIEKLNPFTNKIESLKPISKEE
                     NTYYLNLTKIDLKSLFNNFDVYTKSLVNTDKDTVINNLGETHSKLNEYIWVQRNKKFP
                     LDIIIVDNKIVGFICLSRETCTILIMDGYEEYTVLKEWEKTHKNEEIYSIRFGGNYMI
                     DMKDGIKFSTDVYLPDFVDSTKKAPTILMRTPYGKENDKEIYYKYVQRGYAVVIQDVR
                     GRNESEGKWEPMIHEREDGDSTINWIVSQEWSSGIVGMLGASYLGYVQWAAASSGNKH
                     LKALVSIVTSGSPFIDIPRKGGAFVSGMLAWAFMVSRNKVDRSKMVRDDWDDVLNIRP
                     IENIPVEALGYRIEFLEEWLKRVEKDEYWDLMDWHLQKDKINVPALVVSGWYDDNSMG
                     TTEALDVIKDYEKGKRKAILGPWMHNSNTLRDINGISLGNSSLRYDLDYNYLLWFDKY
                     LKGIENNIDTTAPVEYYSVGFNKWKTEENWPIINKIDKSMYLISDGNANTSLGNGRLV
                     FDNDLEEKYDSYIYNPKDPSVQLIDMSENEVGVPNNYKDLEKRSDMLCYTSDAFSEEF
                     TVTGDIKLEFFASSSAKDTDWVIKIMDVDLDGNSIKLADGILSARFRNSFYKSEFMEE
                     GEIYKFTIITSKISNTFKVGHKIRLDITSSAKNFIFQNSNTKEGYNSIEYIEAKNTIY
                     HGGKYPSKLILPIENK"
     gene            complement(2680..3840)
                     /locus_tag="PC466_000633"
     CDS             complement(2680..3840)
                     /locus_tag="PC466_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF819 family protein"
                     /protein_id="HDF2768056.1"
                     /translation="MNTLFSNPGSILAVMTSMIALGFYLQRYKAIKSLGPALTIIIMG
                     IILSNLKVVPVSTELYGTISTYAIPVSMTIMLMSVDLKEMTKLSREPLIAIFVAVLTV
                     SIMAFLFGLVFAEKISEGWKVAGMFVGTYTGGSANLTAIGTGLNVSRQTLAAANAADY
                     VIGVPTLIFMFALPAILKNSKKFKKLWPYHVEETELEDCQNEEFMESKEWSIKDIAWM
                     LAIGFVVTEVSTILAGYFNSSFSSAARILLVTTISIIIAQLKPVKKLKGNLDLGLFVA
                     LFFLCTIGFSVDIKEFLGSTFTITLYCFSIIFASFVFHLGITRLLKIKYQYVILSIVG
                     AIADGPTSALVAASAKWNSLVSVAVVMGVIGGVLGNYAGISVAYAIKMSLGL"
     gene            complement(3859..4926)
                     /locus_tag="PC466_000634"
     CDS             complement(3859..4926)
                     /locus_tag="PC466_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide epimerase"
                     /protein_id="HDF2768057.1"
                     /translation="MKITDIKFEKLRIKLKKPVVVSFGVIEYGESVILKIETDEGYCG
                     FGEAAPLAAVTGEVLDNVLSVLLMFKKELIGKDPLDIETIHTIMDGIIIGNTSAKAAI
                     DIALYDIKGKIMNAPLYKVLGGFDSKVQTDITISIDKPEKMAVEALERVKEGFRILKL
                     KAGINPEDDIEAVKLIREAVGESIRIRIDANQGWNVNSSINTIKKLEEFNVDAIEQAL
                     PHWDLDGTAYIRNKSNTKIMIDESLHSPIDAIKAIKKNAVDTFNIKLMKSSGIYPAIK
                     INNIAEASGVNCMLGCMLETRIGITAAANLIASKKNITEADLDSFMFCEESKDISGGF
                     VMDGDIMNLVNKPGLGIEVNL"
     gene            5278..5844
                     /locus_tag="PC466_000635"
     CDS             5278..5844
                     /locus_tag="PC466_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2768058.1"
                     /translation="MLGEKMRNIRKSKKKTLSDVSKLTDLSISYISQIERDAIEPSLS
                     SLRKIAEVLDTPLYMFMDDNNTDDLVIRKEDRVMMKFPKSEMFYEIVSPMPTTEFTPS
                     ILFVEFELKPESEDAKDYIYHASEEIMVVTSGVVDICMGEKVVRLNPGDSTFIKANVP
                     HKIINPSKDTIARGYGVISPPIWPIKSK"
     gene            complement(6063..7049)
                     /locus_tag="PC466_000636"
     CDS             complement(6063..7049)
                     /locus_tag="PC466_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-dependent carboxyltransferase"
                     /protein_id="HDF2768059.1"
                     /translation="MGFKVELGGFQTLIQDRGRVGYGQYGVSGCGAMDEYAHRVGNIL
                     VGNSEDEASLEVLMLGPTITFDEYTQIAVTGGDLGAKINGKEIQNWRSYQINPGDVLS
                     FRGVKSGARAYVSIAGGIDVPLAMGSKSTYTRSKIGGFEGRALKKGDYINTFIQEKDF
                     TINKKLNSKYIPTYSSEIVLRIVKGPQFDAFSNGEVEKFLSNKYKVTNEIDRMGCRLD
                     GESIKHLNGADIISDGISYGAIQVPGHGKPIIMLSDRQTSGGYTKIGNVISVDLYKLA
                     QAKPNDVVKFELVDIYEAHRLLREQEDKIQDIYKSMKNIRVVKAKVLNDIAV"
     gene            complement(7079..7774)
                     /gene="pxpB"
                     /locus_tag="PC466_000637"
     CDS             complement(7079..7774)
                     /gene="pxpB"
                     /locus_tag="PC466_000637"
                     /EC_number="3.5.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-oxoprolinase subunit PxpB"
                     /protein_id="HDF2768060.1"
                     /translation="METRYLISGDKAVVAEFGNEISEDINKKVISFMRAIEISNLKGI
                     VTEMVPTYRSLMISYNPLEIDFDSLIENLKKIEDNLESIVLPKPKIHEIPVCYDEVFG
                     IDIKNVASYNNLTVDEVIKIHTSREYLIYMLGFTPGFPYLGGMDERIATPRLEVPRTK
                     IYGGSVGIAGSQTGVYPIDSPGGWQIIGRTPLKLYDENREEQILLRAGDFIKFVPITL
                     DEFIEIEKNNLSI"
     gene            complement(7794..9014)
                     /locus_tag="PC466_000638"
     CDS             complement(7794..9014)
                     /locus_tag="PC466_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HDF2768061.1"
                     /translation="MSTKNITDKTKNKKDVGALIGAAFIMATSAIGPGFLTQTAQFTQ
                     DFGPNFSFVILITTILFIGAQVNVWRVIGVSGLRGQDIANKIIPGLGYLVAFLVALGG
                     LAFNIGNVGGAALGMNVMFNMNMTLGTVLSGLIAIFVFMSKNSNSLVDKITKFLALGM
                     IIIVGYVAISNHPPVGEAVSRMVKPENPKGLIFPIITLLGGSVGGYITFAGGHRLIDG
                     GITGEENIKEITKSSLLGILVDTMMRVLLFLAILAVVSKGLQLDPENPAASAFKFSAG
                     AIGYKFFGLVLWSAAITSVIGAAYTSVSFLKTLNPFIDKYEKYFIIAFIAISTLIMAF
                     IGKPATLLILAGALNGLILPITLGIMLIASKRKDIVGDYKHPTWLLIFGLIVVLISAY
                     TGITSLSSLGALFA"
     gene            complement(9043..9834)
                     /locus_tag="PC466_000639"
     CDS             complement(9043..9834)
                     /locus_tag="PC466_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LamB/YcsF family protein"
                     /protein_id="HDF2768062.1"
                     /translation="MYKVDLNSDLGESFGTYKIGLDEEVLKYISSANIACGFHAGDPS
                     HMEKTVQLAKKNGVKIGAHPGFLDLIGFGRREMKITKQEAKDYTKYQLGALMAFASSN
                     GCNIQHVKPHGALYNMAAKDKELAMGICEAIYEVDKDIILLGLYNSEMINSAKEIGLR
                     FANEVFADRAYDNNGFLVPRSVEGAVIHDTKHAIDRVVRMVKEGTVETLTGEVIHIKA
                     DSICVHGDNPKAIEFVKEIRKRFELEGIEVCPLENIEVCSSENIV"
     gene            10423..11052
                     /locus_tag="PC466_000640"
     CDS             10423..11052
                     /locus_tag="PC466_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2768063.1"
                     /translation="MDKNYTMPIYQKIALDIANKIYTGEIQEDSVLFGRSVLAGKYNV
                     SPETIRRAVKILEDIGVVKSIKGKGVIVLSPDKASSFIKKYRDITNISSYKSTLYNLI
                     DTKSNLENEILDTINKILDYSNRLEIINPLVPVQFTINSNCKYIGQTAAQTKFWQNTG
                     ATIVAIKRGEELIISPGPYIEFLEGDILLVVGDQHIYNSIPMFLYENEK"
     gene            complement(11166..12680)
                     /gene="glpK"
                     /locus_tag="PC466_000641"
     CDS             complement(11166..12680)
                     /gene="glpK"
                     /locus_tag="PC466_000641"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HDF2768064.1"
                     /translation="MEKKYVMALDQGTTSSRAILFNKKGEIVKIAQKEFNQIYPKAGW
                     VEHDPMEIWGSQSGVMREVIETAGIRPEEIASIGITNQRETTVVWSRYTGKPIYNAIV
                     WQCRRTSEICDELKNKGLEESIKEKTGLLIDAYFSATKVKWILDNVEGAREKAEQGEL
                     LFGTIDTWLIWNLTRGKVHVTDYSNASRTMMYNINDLEWDEDILRELDIPISMLPLVK
                     PSSYVYGHTDERMLSGAKIPIAGCAGDQQAALFGQNCVEEGTAKNTYGTGCFLLMNTG
                     SNIVKSKHGLLTTIAWGVDGKVTYALEGSIFIGGASVQWLRDELKIIESAKDSEMYAN
                     RVEDTNGVYVVPAFTGLGAPYWDMYARGSILGLTRGAKKEHIVRATLESIAYQTKDVL
                     EAMQNDSKLKLKSLKVDGGASNNNFLMQFQSDILNVDIDRPKIVETTALGAAYLAGLS
                     VGFYIGRNEITSKWSVEKEFNPNMSEEKRCKLYKGWKKAVSRALSWEKEDELDI"
     gene            12923..13465
                     /locus_tag="PC466_000642"
     CDS             12923..13465
                     /locus_tag="PC466_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2768065.1"
                     /translation="MPKILENVKEDILKVSRDMILEEDYSNISIRKIAQRCGISAGTV
                     YNYFNSKQEIIEYITKSEWDLLIRRIEYSNKNTEDYIKKLNIIFTEIRNFINKVHNIQ
                     YNDFLNTFETERFFEMKKHKDDFHEQLSNKVYEALEKESFFNNDKLVCNIIIKMFFSY
                     STYLHIEFEDLKPYIEKLIH"
     gene            13479..15971
                     /locus_tag="PC466_000643"
     CDS             13479..15971
                     /locus_tag="PC466_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2768066.1"
                     /translation="MNHNTSIKNKDSNPKIFLVLTLYLLGIFMGAIDTGIVSPARTII
                     QNSLGVNEKTGIWMITIYTLTYASVIPISGKLADKIGRKYVYLVSIFLFGSGSLICGL
                     SSLFSNFYILLIGRVIQAIGGGGIMPIATAEFGTTFPENKRGMALGLVGATYGIANIL
                     GSSIGSTILSIFGTQNWKWLFFVNLPICLIILIGGVFCIKNNKSESKEKIDKLGTLML
                     ICIIVSLLYGLMNIDFFNFKNSIQDISVYPYLLTFIVLIPIFIFIENRAKDPILSFEY
                     FLNPRILIVLILSLIVGIGMMGMVFVPQYAENALKINAGSGGYFVAILGLFAGIAAPL
                     SGRLIDKFGAKKILLLGFSVSMIGSLYLVLIALKTNTVFSVCVSLIFMGLGMGFTMGT
                     PLNYMMLSNTRLEESNSALATLSLIRSIGTSISPAIMIGFIAHAGLSVQDNIMDLVGK
                     PSTPKIVQLEELENMIDDLKSDPEMAKNLKNVSIPNMNDTSNINMDMTGGKLPKSLLN
                     KVQSADTTNITNITKEISTTMFDEKVPSIITKIQKNVQKGIDGTQSGINGIEDGENKL
                     NSGIKGVQTGIDNMVKARAGINQGIDGVKKGIAGVDKGIKGMEQGLEKQDEAIKELTT
                     AYNKIPTTEKTPTDNENNSNEQNQSNTSNSESDDTKNDSTENKNNNSSENKPNVNEQK
                     ESLNAQIQQLKKTRDDLNTKLQKNKTQKNELSKKLRSMESQKKELQSKLNNSINQKKD
                     MEKSLDTMQQQKKSLQAVLAKTQEVKTEIPKAFDKSKLDYINSIENNRTKIENTLQST
                     LNSGFKQMYITVFCVNLLAFIILLFYKENKTR"
     gene            16392..16790
                     /locus_tag="PC466_000644"
     CDS             16392..16790
                     /locus_tag="PC466_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2768067.1"
                     /translation="MDTLGKRIAYLRNSKKLTQRKLMDILKFENLGKYETGDRKPNCD
                     ILMSIADYFNVTTDWLLYGKEKVNVNSSVKEDKEDYLHVTNDEMMILNLYRQLNERDK
                     IKIEGILELKISEYKDLKKHSSNNNEDKMV"
     gene            complement(17007..17216)
                     /locus_tag="PC466_000645"
     CDS             complement(17007..17216)
                     /locus_tag="PC466_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768068.1"
                     /translation="MCKLDSDGVIECCRAIDDFITALSNIKSLNMERLNTLTKYSSTC
                     SILLKEGNYEGCTIVYRKMLEELKT"
     gene            complement(17248..17457)
                     /locus_tag="PC466_000646"
     CDS             complement(17248..17457)
                     /locus_tag="PC466_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2768069.1"
                     /translation="MDARKKWIPFLGVQVKQRLIELNMTQRELAKKIGVNENYLSAIL
                     NGRRTGKKYKSSIYQLLNIEYSEDD"
     gene            17756..18175
                     /locus_tag="PC466_000647"
     CDS             17756..18175
                     /locus_tag="PC466_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2768070.1"
                     /translation="MDTLGERIVYLRKAKNLKQYELEEMLGCDNLSKFERNIRKPNYE
                     ILKSIAEIFNVSVDWLLNGDNLSHKSDLICDSSSNYPLNSINSNEIKLLNNFRKLNDY
                     DKAKIEGMIELKLHEYEKEKDLGKIEYNKNKDEKIDK"
     gene            18403..18858
                     /locus_tag="PC466_000648"
     CDS             18403..18858
                     /locus_tag="PC466_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768071.1"
                     /translation="MGLRDKFAQSFARSKTMSGPEKKANEIMGKLLLKKAILPIVLMF
                     VIIIAGAMLKINSWVTLGINLVIAVGAFFYIRNSSKKYQNFKPYVGNLISLEKKGKKE
                     YVAIIKQGKLPVKLQIAYGGEDLEHVKKNQMVQISYNPDAKIAILVNRQ"
     gene            complement(19083..19343)
                     /locus_tag="PC466_000649"
     CDS             complement(19083..19343)
                     /locus_tag="PC466_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768072.1"
                     /translation="MDKLITELSSLGAIGILCALLFKNTMQEKKEDRDMYKKTVENFI
                     ELSTQQQEINKNILVQMGIMKTDVEEIKEDVTDIKGMLQNGV"
     gene            complement(19606..19959)
                     /locus_tag="PC466_000650"
     CDS             complement(19606..19959)
                     /locus_tag="PC466_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768073.1"
                     /translation="MFKFDKNKIEQIKQGRKVEMQYKDISDISIGQAKQDDDITNNFI
                     ANAEIYEMLLSQSSVNEASNISTFSVRKSGGESGMVEVYVALILRGRKTIEEVPAVIR
                     EQVRIRCKELEIPVE"
     gene            complement(19976..25153)
                     /locus_tag="PC466_000651"
     CDS             complement(19976..25153)
                     /locus_tag="PC466_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome condensation regulator"
                     /protein_id="HDF2768074.1"
                     /translation="MKQNKLLQRGAYFNDKNILIDDFDKRYNDYDFVEFFTGISNSTF
                     GLKSDGNLYACGDNTGFQLGLGKDSSERRMFSKVKIDNVKYVSCGSKHSVAVTKDGFA
                     YGAGTSNVGQLGVIESTVYYEFTKLPIDDVKTVACGYDFTFVLKNDGTLYSAGLNSSG
                     QLGLGDTNNRATFTKVNIDSVKDVVTYNQSVFIIKMDGTAHACGLNSNGQLGINSTLN
                     KSVFNKIEGMDNVKQIACGSSHTILIKNDGTMYTTGYNGVGQLGTGNNNNSIVFTLSS
                     INNVKYASCGNNHTMILKYDNTLFSTGQNNYGQLANANKDVASRNTFAKVNVENIKDI
                     KCGSQFNFLINGSKEIFVSGCNLAGQLGSFFHTTFLYEFSNVQSSNLDNYSGLLVNDD
                     YLYVTKDNSEFLNVKLSDNFQDYKKIELTDSNMFIVMNDGTLYACGLNNYGQLGLGDT
                     VNRSVMTKVDIDNVLDIKGNGNSTFVLKNNGTLYSCGLNSNGQLGLRDEVNRNIFTKI
                     EIENVKDFCVGSNYVIALNHSKEVYGWGNNPYNNIEKTSNYPYKQGISNIEKIAAYDY
                     SVYMINSEGKLYVSGYNYNYQLGKGNNSNQSKALVSQCRTNSTSSTSNGLRTLPKITN
                     VFPFYDGCAIIDEGGYVYLTGYHGYLRTLNSSPSISDYSRYGTFIEATNSNHNTYFIQ
                     ETDFSGIEKVIGMSNNILFFKKGSSYITGYPKTFGSTITGHRSYTSINSESSNLGSNF
                     IIYHSNSKLYGKGIANSGQFGNSTNIDGTSNYDTGLKDIKDIIVKGNTVVVVDKNNNI
                     YVTGMNQNNKLGIGEYNNEPVKKFTNITEQSNSFIFMDDIKEITTSRNTMFIVKNDGT
                     AYATGNNSSGQLGLGDTINRNKFTQINLDNIKKISTSIDGNTTFAIRNDGTLYSTGLN
                     TKGQLGLGDIVNRNTFTKVNIQNVRDVVLGTTHSHAIKDDNTLYSCGENTHGQLGLGS
                     ESNHPDVLTFTVNNITNVRDVYCSDTTTFIVKDTNIAYCCGYNNNSQLGMGNTTDQYS
                     FIKCMENVKEVIPNEINTYIITIYNTAYSTGLNTDYCLGLNSNSNQSSFSEIPISNVV
                     KVAPNRNNAVLLLTSEGDVYTAGKCSNGSGTGSETPEKIKKIASKAKDIGMNYRCGHY
                     VSDNGDLYGTGFNNNGQLGVGDVTKRDTFIKTNTRVKKILPLEYANIAIKDTNDIYIC
                     GLNNYGQLGVGNRYDSRNNDNRIFNYKHMNFVMGDLTSIKNRHNFILLNNKIVIPTTK
                     DIDYGLVLGNLYKGDLYTELPYEDIKEVSISKTHIIILLNDGTMYGCGTNYHGELLQD
                     LSINQVDEFVQINVSDVKHVSCGDNFTYFIKSDDSLWSIGKNSEYQLGIGHNNPVTEL
                     QRITTISSCKEVHCGKNYTLVVTTGNELFVQGYNDKGALGLGSDSENTIIKFFTKALT
                     DIREIKSYGSDHILVLKNDNSVWVTGKNRDVYKIEQPVEFLKEFTIVPISEDVNTVKD
                     VLATDNTLYIISEVGTTNAAIEITEKSISSIKIKIQDPNKDISRIEMLINGESVKSVS
                     DLTTEKISFEVPPDKIKIGENKILFRAYCKGDDLYASLFIFKESTGNSIIKDSYVMIG
                     NRMYKVVNTTSNEQDITITLDRGLEEDLNLGDPIYQLINKTKVQVKINKSDLFKDMKL
                     VEIKKSDSSYQEIYELEEANIKSAQPKIIVEKGDKWTAIKRPSMIFRYDAENNEPQA"
     gene            complement(25175..26161)
                     /locus_tag="PC466_000652"
     CDS             complement(25175..26161)
                     /locus_tag="PC466_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDF2768075.1"
                     /translation="MEEKFYIILTKIGREKIANATALGELVGLTKFQVGDSNGEYYEP
                     TEEQTALKNVVWEGNINSLRIDEKNPNWIVIETILPGTVGGFMIREAAVLDNENNIIA
                     IGKYPETYKPRAEDGSIKDLVVKMILQLSNTSNVTLEVDPTLVFVTQKDIQDLDDKFD
                     KNIKEIKVKIGDTDILTTDSKDLSGAINEVVKKIENISFDDVISGQIQTDISVLKNSY
                     NKLSEKVLDILIYLELESEVTVDEAGYWYDTLANGNNIVAIEGLKLDLNRKCITGEIG
                     NVIFRDVVLPFSANRVRYIHDMDNNFVETKSSNTYLKEQKDITLSKYSYEIR"
     gene            complement(26162..26860)
                     /locus_tag="PC466_000653"
     CDS             complement(26162..26860)
                     /locus_tag="PC466_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2313 domain-containing protein"
                     /protein_id="HDF2768076.1"
                     /translation="MKLIDKLPSFDRNYIVEEIQGAYDTELNILKEDIDDTFNQLFVD
                     TATWGLDMWEDILCIEKKELDFDTRRSNIKAKMRSRGTSTIEVIKSICEAYTKSETDI
                     KVYSDEFTFVLSFIANNCDYKTLLDCSEMIERVKPAHLLHYLEPIILDKSMVYCGGGM
                     VCSEEVKVHPYFEPIIKCSAVVNCGAGMLSREEIKVYPLSIKCIENNCKINIAIANDT
                     GVENVVVYPKSEVV"
     gene            complement(26857..27909)
                     /locus_tag="PC466_000654"
     CDS             complement(26857..27909)
                     /locus_tag="PC466_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HDF2768077.1"
                     /translation="MYSDQTYEVIKNRTLENINLDIYKGEGSFLNNMVSGNNLELSKI
                     YLELSKIHKMAFIQDTYNQFLDKRVNEFGVYRKLGTESNGEVEFIGEKGTVINNGTII
                     SYRDLLFVVIKDVTIGSEEGDNSPVQALEVGKKYNLPTNCEFKLVDNISGVTKITNTR
                     SFEGGTDIETDEELKERFYKIQRNQATSGNKAHYEEWALEVDGVYNVKVYPRWDGPGT
                     VKVLIFGENNQAVDTETIERCQQHIDEEKPIGPTITVVTPLPIEISISAVMKLEDGYT
                     LDNVKESFLESINTYFRDIRGEIIYTKVMGILINTTGVHDLSNLLINGSTDNITINED
                     KIPSVTTVNFSEVENQ"
     gene            complement(27902..28330)
                     /locus_tag="PC466_000655"
     CDS             complement(27902..28330)
                     /locus_tag="PC466_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2634 domain-containing protein"
                     /protein_id="HDF2768078.1"
                     /translation="MSTIFPFIGVPEDYILPKTEELPIFREVAWDFEKDEPILEKGDF
                     KIIEKKEALKVWIYKCIKTNRYEHEIYSLEYGTELSELIGQKYTKGLTESEASRFIKE
                     ALLINPYILEVNVKSANFNRDVLSANVKVSTIYGEVEINV"
     gene            complement(28330..28656)
                     /locus_tag="PC466_000656"
     CDS             complement(28330..28656)
                     /locus_tag="PC466_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2577 family protein"
                     /protein_id="HDF2768079.1"
                     /translation="MANPINEFIGIIREEGKYHNQPSFFIGKIKSKLPDLKIETNNII
                     LEKEDILIDSWMIDRQLETFDTETNQEHQHEVKNPFIDNFESGDMVIMFRIGEKFAVV
                     SKLVSL"
     gene            complement(28672..30201)
                     /locus_tag="PC466_000657"
     CDS             complement(28672..30201)
                     /locus_tag="PC466_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HDF2768080.1"
                     /translation="MIINRSKDSSSNEISFVSKDMGFLLTQSEVSYNFKDKLVEDIAK
                     QVFAENRLSVGTIAKTNVKYTKMFIGVNGYDTIMSAYTEASKKTKKKYMIEANLDKFN
                     VIEKGTVTLSVMFEEGFNIINTTFSESMENVKNKVIVVDQYGSKISEKIDNEIFKEVN
                     VIMQKVIQQQENQDVDIDSEFNGIEKSCSLKGYGDVSCITGRGVKVKDSYTKLVGLFY
                     IDTDKHTWQNGEYQIELELNFQNLMDEKSAGQDEPKEESNLGGEDYAGGKEFTAEFTA
                     YCPRKEEGGDTDCRKKKLDPSKKTCAAPMVGKYEQTYYTKEFLNKHPLLNYGDEIQVI
                     TGVSGRDGVYKVNDVGPAITIEKNGTYHIDILFGNVEEASKFGRRKGKIIIGGYSGNV
                     SDKAKIVISEAKKHLGKPYKWGGNGPSSFDCSGLMVYCFKKVNVSLPRTSNQQSKKGK
                     KVEQKNLQAGDLVFFHNPVSHVGLYIGNGEFLHAPQKGDVVKISKLSSRRDFNTARRV
                     L"
     gene            complement(30483..30905)
                     /locus_tag="PC466_000658"
     CDS             complement(30483..30905)
                     /locus_tag="PC466_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768081.1"
                     /translation="MEMWLRQAEDRFRFPVFPSSFSINGKAAVNSSSILKIGEVATFG
                     GVALKSISISSFFPNKDYTFCDYTGFPSPYDCVNKIEKWMKEGFILRFTITETNINME
                     VIIEGFSYEERDGTRDVYFTLDLKEYKRIKIPKVTPKQ"
     gene            complement(30905..33358)
                     /locus_tag="PC466_000659"
     CDS             complement(30905..33358)
                     /locus_tag="PC466_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768082.1"
                     /translation="MGNVREEGINMYLTDNYTPKMNQIISVTDNFRRATVAVSLSTNV
                     MASSIKNSIGSASSRVNSLNSSLRKVQTTASSVSSTMAKLSSSINAVSGVIGSLNGSI
                     MRLAITIAMIIDYFNKLIQKKNEFNSNIMIILIFKAKSDEVEKTKNKLLGNLKKIGGK
                     IWNIVIKAKDMTKRVISSILGKLKRVEKRPYQGSINLKDMVSSAMARILPKLMLFKNT
                     FWSGVIAIKDMASSIISKVFPKLRLFAGKVWSGAIAVKDMASGILGSIKGKISDLTNG
                     ATIGVAVKKGVDLLGQEQNQKVVLESVMKRNTGKTSQKDVDKYYDSLVNMANDTPFDP
                     EDVVAMGTKAKMISNITGGKKEKDITQAMVDVRALNMNTSSEQDVSAAFLSAAKGNME
                     SLNTLVGENYKTFDEALEGISVKQMGLAKEMSNTIPGIISGAQTSINNGLKSIVKPFD
                     DILGQGLKKIKTFIESGLGNLAGLSEKMAGKIGNVMNGKIIIGNKYDQMQSRSVKNGK
                     EFSDSTQYRISNEAEKRKMMVENKQERFENHAATMIGNAPKAIVNAGSTLLQNIDFTA
                     LIDSLLPVVNLVNNLLDSINNKSPIAQGLISIFGTIVTTAFQLIGPVVEAVSPIITRI
                     FTFLGEYAPQINNFIETLGVIWKTVWETLGPLLETGWKIIEPILGAFFNILDKVCKIV
                     KDICKWWQTMINKIKNGSITGTVLNLVEKSKKNYKDNPYAGTKAGDSGKAYSSKKGNN
                     AFGLNYVPYNDYQTRLHEGEMVLTKQEANQYRSRKNGGNINIAKLADTIVIREEADIE
                     KITSKLVASIQLAQLGGVL"
     gene            complement(33358..33525)
                     /locus_tag="PC466_000660"
     CDS             complement(33358..33525)
                     /locus_tag="PC466_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768083.1"
                     /translation="MYYYWKKKGIRPSLFYAMDKGELKLIEAFFALEIEEEVEKMKHG
                     YGVCPLTGGGM"
     gene            complement(33552..33998)
                     /locus_tag="PC466_000661"
     CDS             complement(33552..33998)
                     /locus_tag="PC466_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HDF2768084.1"
                     /translation="MNENGLSKNINIVDLLLNADTENLERPSTIVELKRLSTIFGQEF
                     KVMCRALTISKDEEIQNTCLKIDENMKTDIDLPEMQMLTIIEGVCDLDGKLLFKNKEL
                     MDKFKAPTPKELARKLLLPGEITNLYRILQDVMGYGKNAVIEEVKN"
     gene            complement(34112..34540)
                     /locus_tag="PC466_000662"
     CDS             complement(34112..34540)
                     /locus_tag="PC466_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tube protein"
                     /protein_id="HDF2768085.1"
                     /translation="MANMEARNVMSGTWGELWLDGNKVAEVKKFQAKMEFTKEDIIIA
                     GQMGTDTKYMGYKGKGSITLYHVSSRMHKLIGEKIKRGSEPRFVAISKLNDPDSYGAE
                     RIAVKNIAFDDLTLADWEVGVKGEIEAPFTFTEYDFLDII"
     gene            complement(34554..35618)
                     /locus_tag="PC466_000663"
     CDS             complement(34554..35618)
                     /locus_tag="PC466_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath subtilisin-like
                     domain-containing protein"
                     /protein_id="HDF2768086.1"
                     /translation="MAIGLPSINISFKELATTVKERSARGIIAMVLKDAKALGLNEIH
                     EKEDIPVDLSAENKEYINLALMGNVNTPNKLLVYVIEGEADIQTALDFLETKEFNYLC
                     MPKAVEADKTAIKNWIIKLRDIDKVKVKAVLGKVVGNHEGIINFTTEDVLVGEKKYSV
                     DEFTSRVAGLIAGTPLSQSVTYTKLSDVVDIPKMTKVDAESRVNKGELILIKEAGAIR
                     IARGVNSLTELTEEKGEMFQKIKIVDTLDIIHSDIRKVIIDDYIGKVTNSYDNKCLLI
                     VAIKSYLEELEKSALIESDSTVEIDFEAQKSYLKSKGVDLSYMTLQEIKEANTGSKVF
                     LKAKIKVLDAMEDIDLSIEI"
     gene            complement(35623..36066)
                     /locus_tag="PC466_000664"
     CDS             complement(35623..36066)
                     /locus_tag="PC466_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768087.1"
                     /translation="MLKYKEILETIIEILKKNFTESIFIDDESVQGSEGSCFFVSILS
                     VICTPIMLNTNNKDIVISIKYLPKPQSKSIRMYEISDELNKLFNRNIKVTDRKLNITK
                     LEQSIKKEESIYVLNFTITLNYLDSVYEEDVVYENMEEINLNLGE"
     gene            complement(36315..36755)
                     /locus_tag="PC466_000665"
     CDS             complement(36315..36755)
                     /locus_tag="PC466_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768088.1"
                     /translation="MENKKDILFKETDERLHNYKYLDIKIKNINLDIKRCENEYSGCG
                     AMVYTEKTSNTYNISSSVENEVLKREERLRKLKMEKEDIEIEKEKIENALTCLNDIEM
                     EFFNLFYNSKTKNNMTYISMKLHLDRTSCYNLKKKMIFKLSEIL"
     gene            complement(36860..37057)
                     /locus_tag="PC466_000666"
     CDS             complement(36860..37057)
                     /locus_tag="PC466_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2768089.1"
                     /translation="MFKNNLKYYRKCKGMTQIQLARKAGITNDYISQIERGIKNPGLL
                     MAKKISSILEQNIEEVFFIQL"
     gene            37226..37546
                     /locus_tag="PC466_000667"
     CDS             37226..37546
                     /locus_tag="PC466_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HDF2768090.1"
                     /translation="MFAKRLRELRKEFGLTQRELGEKVGVSQRVLGYYETENRFPDEH
                     ILNKLADVFNVSVDYLLGRTLVKENIDTVAAHRKNPHEELPEEAQEQLNDYIEFLLNK
                     YKKK"
     gene            37628..38134
                     /locus_tag="PC466_000668"
     CDS             37628..38134
                     /locus_tag="PC466_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768091.1"
                     /translation="MNNLDKLFELASQEEIIIHYTTYIAGDLEGLYINKHGIKIISLL
                     SNLKQNSKKLTSILAEELGHHFTSLGYYVSSYNDYYTKIIIDKCENKALKWACEFLIT
                     EEDIINIINSGITCVYEMADILNVDITFFQKRLEFLSLKKQSLQLGNNKYLILTNLPY
                     FYIFDPIS"
     gene            38835..39590
                     /locus_tag="PC466_000669"
     CDS             38835..39590
                     /locus_tag="PC466_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HDF2768092.1"
                     /translation="MEKKVLATVGEKEITNIDIENALKSLDPYQAMQFKTEEGKKHLL
                     NDLVNQELFFLDAKEEKLDEEEIFKLEMKKIEENVLKQFAINKVLSSVNVTEDEKVKF
                     FEANKSSFSKPESATAKHILVDSDEKAKEILAQIKSEEISFEDAALKHSSCPSKDMGG
                     DLGTFGRGQMVPEFEEAVFSMAKGEVSEPVKTQFGYHIIKLEDLQESTESTFDEVKAE
                     VEKSLLYQKQNEVYGNKINALNAKYGNLVKYND"
     gene            complement(39733..40161)
                     /locus_tag="PC466_000670"
     CDS             complement(39733..40161)
                     /locus_tag="PC466_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HDF2768093.1"
                     /translation="MNILFFLTPKSEVAYIYEDYTIRQALEKMEYHKYSAIPIISKDG
                     KYVGTITEGDFLWTLKNDLNLDLKGLEDVPVTDINRKMDNSPVSINADIEDLVIKSLN
                     QNFIPVIDDQDTFIGIIKRRDVIGYCYEIIRGYKNLANDN"
     gene            complement(40582..40782)
                     /locus_tag="PC466_000671"
     CDS             complement(40582..40782)
                     /locus_tag="PC466_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HDF2768094.1"
                     /translation="MKTGVVKWFNNEKGFGFISVEGEGDVFVHFSAITGDGYKTLEEG
                     QSVEFEVVDGAKGPQAANVVRL"
     gene            complement(40965..42134)
                     /locus_tag="PC466_000672"
     CDS             complement(40965..42134)
                     /locus_tag="PC466_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase domain-containing protein"
                     /protein_id="HDF2768095.1"
                     /translation="MGGVALKILKNKNKYIKGIMAFVFLSLATTAGVFLINDLSMKNM
                     EEKVMESANVEGDDVKDQYKLLLENLFDYRNKAILEKNENILKGLYETDKKFGLWAYE
                     NEVKKMKYLENWSSKQGVKFKDIKTRVKIKKIKEKEKDLYGIICSVSTEYKYSYENQK
                     DKENAFRIGTYHYLNVKIIDNQYVITKEWYTDPFADSLNLENIKSEDIRNYIGQQDGV
                     ELQLTDEQKKAIDYAHKYCGAAADEEHGMKFNPNYRDYNPEGGDCANFASQIMFESGR
                     FKKNSIWNYSERAGTKAWVNAQAFKNYALYSGRGSLIAKGSYEEVYKEAYNLRPGDFV
                     GYEKKGRITHVSTVTGLDSRGYPLVTCHNTDRMLVPWDLGWSDKSIRFHIIKINY"
     gene            42370..43191
                     /locus_tag="PC466_000673"
     CDS             42370..43191
                     /locus_tag="PC466_000673"
                     /EC_number="2.7.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine kinase"
                     /protein_id="HDF2768096.1"
                     /translation="MQKKVAAINDLSGIGKCSLSVAIPILSALKVQCCPFPTAILSSQ
                     TGYPEFTFLDFTDEMVKYSNVWKNLKVNFDSIYSGFLGSKHQIEIVANFINDYPNAFI
                     VVDPVMGDNGVMYPIFTEEMRQEIKELVKHSDLTTPNLTEACFLTGNDYTKSDYNRDE
                     LIYIAKSVSDLGPSKVVITGILEDDNILNLAYDRDNDHVFFTSVKYNNCSYSGTGDIF
                     TSILCGMLVNKHDLGVAVNTATDFIYKTINYTSQFDTDRNDGVMFENFLSDLTNI"
     gene            complement(43267..44655)
                     /locus_tag="PC466_000674"
     CDS             complement(43267..44655)
                     /locus_tag="PC466_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase"
                     /protein_id="HDF2768097.1"
                     /translation="MLRSKKSNNKKVEKLRTIFIKYLSLFFVMTISFALLLMLSFSVL
                     LSSGVILPANYSEKQFDKYKEKIISSEKAIEDIIPNLYEYGVYTLDGNLISGTFNKKE
                     SKQVWNLMRDIEERHAYSESYIKFFKKDEVFIIKYKLVSEYSSPVLRAYLPKPEMLGM
                     IIFSIIFFIEIVILSKVFGKKFNIEMELLKNTTEKIEQQDLDFVVESSKIYEINNILF
                     SMDKMKLALKNSLEKQWMLEENRKEQISALAHDIKTPLTIIHGNTDLLIEINENPELL
                     EYMEYISKGVTQIEKYINTLIDISKTENGYILNKEAINMSEFIKDVLLQIEALASTKN
                     LDVEFYKQDNLPKNITIDRELLFRAIMNIISNAIDYSPSQSKLYISVSVSNKYLKFVV
                     TDCGSGFSKADLSKATEQFYTGDLSRNSKSHYGMGLYIVNNIVQKHNGILYIENSVKT
                     GGAMVTIEIPIV"
     gene            complement(44799..45557)
                     /locus_tag="PC466_000675"
     CDS             complement(44799..45557)
                     /locus_tag="PC466_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutG family
                     permease subunit"
                     /protein_id="HDF2768098.1"
                     /translation="MRQLIRIFCSDLIKLKRNFIILMHICIALMGMGLFLWYYKVSGA
                     DNILKIVAYLQVIAIAFPLLSGVVCSMFVEQEYYAGNYKHMLTTSNPKYLTLISKYII
                     LVCLGFVATLVSVLGFKFGISKAYFTSSFYMISILILIGCNLFEYILHLFLSLRFGKG
                     TSIGVGIVEMLLSALLLTGLGSGIWQYFPCAWGVRFITIWSSFSSSKTVEYIKVESIK
                     AYQSTGLMCGFVTILAFVILCIWFSKWEGKKSEE"
     gene            complement(45559..46275)
                     /locus_tag="PC466_000676"
     CDS             complement(45559..46275)
                     /locus_tag="PC466_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutE/EpiE
                     family permease subunit"
                     /protein_id="HDF2768099.1"
                     /translation="MERFIRVEFQKMKGTFGMKLIWIVPVFCILLCGLGGGQNAAFNW
                     WYTTFLPGALTLISSLIVLKDEKSKYRGILPLPIEMKDVWAGKMIYCIICCSIASIIS
                     AIGVVFVGIIYKETISIGQNIIATILIILLFMWQIPLCMFLASKFGIFVTVLTNMFFT
                     IVGVAVFSTTEMWYVFPYSIPSRLMVVVLHILPNGLPVPEGSELLNNAVILPGVLISV
                     ILFVLFALVTRAWFNNREVK"
     gene            complement(46277..46984)
                     /locus_tag="PC466_000677"
     CDS             complement(46277..46984)
                     /locus_tag="PC466_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic protection ABC transporter
                     ATP-binding protein"
                     /protein_id="HDF2768100.1"
                     /translation="MNNYILQVKGVSKKFKEQMAVDNISLAIKSNSIYGLLGPNGAGK
                     STLLKMITGILNPTSGKIMFEGHRWTRKDLSNIGSLIESPAIYENLTARENLKVHTTL
                     LGLPDSRIEEVLETVDLRDTFKKRSGQFSLGMKQRLGIAIALLNHPKLLILDEPTNGL
                     DPIGIEELRKLIRSFPKQGITVILSSHILSEVEQVVDEIGIISNGVIGYQGEVSKEQN
                     LEKLFMKVVAENRKRGE"
     gene            complement(47101..47637)
                     /locus_tag="PC466_000678"
     CDS             complement(47101..47637)
                     /locus_tag="PC466_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HDF2768101.1"
                     /translation="MNKIAVSFLIIATTLLSTACMDYSISAVELVDSKESAVVKKDED
                     AKEETTSKMINSKKTTKIPIEIISKDEKIVKYLQIDEESSLKDKLRLILDTLSNEYFN
                     GLDMEVEVKEKDNLVKINLIEPDKKSRVSWKDDYLNEQNIIYTINNIIKNVIQEEDNS
                     IWIEEVEIYYNGKLIELR"
     gene            complement(47739..48809)
                     /locus_tag="PC466_000679"
     CDS             complement(47739..48809)
                     /locus_tag="PC466_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HDF2768102.1"
                     /translation="MNKKLAIFAAVLLVIGIIGTTWSGILVMPSLINFGLEKEAEFKK
                     ENKLYQEKVNIDKLDISVDNINVTIKKSSSEDVRVTTRGNNEFYKYNVTLKDKTLVVK
                     GERKYENKIKKIKNFDQLLNTSINSMFSHDYREIIIYVPNNVDINASSTSSYLFVYDN
                     VASNTITYKTSYGGFSRAITENKVNRLENLNLISNSNLHLSTKSILGVKNVNIESESL
                     DISSENEDVFINNIEEYIPENVNIKEKIGRNSNYESEFYLYSNMPIAKFLDIEVPNSK
                     VRLDIPVNKYKFNCDIKSKEAIEEFNNDEEYDNDSYDYEHSEEHSNKYRNTREIKGLL
                     NKNLSNLEKEYTIKINSNSLEL"
     gene            complement(48802..49860)
                     /locus_tag="PC466_000680"
     CDS             complement(48802..49860)
                     /locus_tag="PC466_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HDF2768103.1"
                     /translation="MNLNKTEFLEILKDYLKKDFSESEVNDILRDYEEYFVDGLIEGK
                     SDMEIIASLGSPKSIAKELILQTKEKNIEEEKIINTDVLNDKFSKFKSDMKKGYSILK
                     DEAKEKYSKSKENIDGKIMNTDILNGKFSRFKSNIKKDYSILKDEAKEKYNKSKENIN
                     DKLTPSIEEGVGGLSRQVIKGLLVVLSLFLIVPAFAFVCAIVSVTIALVCSLIAFVIL
                     IPFVIKFIAMVPDVMMFCIFATIAFVGLEILAWQILLFAIKLGKQLLNNYIHWIKRKN
                     IYIKANEKMEKRKKATLNDEDLNKDINEDSYNNDYYNREEESIKETDEYNDDSINFEA
                     IYKDLEDIENKKGEDKHE"
     gene            complement(49847..50179)
                     /locus_tag="PC466_000681"
     CDS             complement(49847..50179)
                     /locus_tag="PC466_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HDF2768104.1"
                     /translation="MNTQFRKGVLEICVLALISKKDMYGYEIVHNISKVIDVNEGTIY
                     PILRRLTKDLYFETYILESNEGPARKYYRITSLGKENLSNLMEEWREFVKAVEILISE
                     DEGGNELE"
     gene            50378..51499
                     /locus_tag="PC466_000682"
     CDS             50378..51499
                     /locus_tag="PC466_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactosyldiacylglycerol synthase"
                     /protein_id="HDF2768105.1"
                     /translation="MKDDKTILILTAQFGAGHISAAKAVKECIIEKYSNYNVVIQNFI
                     NASIPMMNKPMVKLYENNTKYTPGLYNYYYYFKKSFDSRHDLSHKLYTPKLSEYIADI
                     NPDLIISTFPLAAACVNNFKIKNPDINIPTLTVITDVVDSMEWVFENTDLYFVPSPEI
                     KNRFFQKGINPDSIKVTGVPVDKRFQIESKELCCDKYRLLLLGGGRGLFDIDEDFMHW
                     IDEFIEEHSNSIEITIVTGKNKKLYDNLTHKKPLKNIKVLGFVNDMYNLIRECDLMLT
                     KPGGATIFEAIQSQTPVLVKMPKVGQEIENAKFIIDKGLGMIYSDDLDLKNIFYKLVS
                     NEFDSIINFMKKNLEEFKTVIHPEKIADYISELIDNHYS"
     gene            complement(51627..53525)
                     /locus_tag="PC466_000683"
     CDS             complement(51627..53525)
                     /locus_tag="PC466_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HDF2768106.1"
                     /translation="MDSLLYVIEKDKHTNEELREILKSNKNIRFVSLMGVDLGGNATD
                     EKIPVELFLEDIDKFLESAIQTDGSSVELYNIATLNNAKVDLMPDKSCHWYVDYNMEY
                     IDEEVGLPVGTLKIPAFLIHDNKKVCSRGVLQKADKYFKKSMYEIFREYPHVINNIGI
                     DSVDDIEEIMLTAATELEFWVNTPEDKADLEKLYVSQSLKEQYWKRTHGIIRTCLEKS
                     LIILQKLGVNPEMAHKEVGGIQSSISIDGRTNHAMEQLEVSWKFSTPLQAADNELLVR
                     DVIEDVFTSHGLEVTFKAKPIHGVAGSGGHTHVGVSAKLKDGSIKNLFAPKDLKEDYL
                     SELGYGALMGLLYNYEVLNPIVTASNDGFNRLVPGFEAPVCIVTSLGHSYEIPSRNRS
                     VLVGLIRDMKNPKTVRFELRSPSPLSNTYLVIAGCYQTMLDGIKAAAKSGLSTKELEK
                     ELSKNVGEESFYLEKDRAYRDENDVFEHYSLEERNARFGIPPATVYENMKNLEIYASK
                     LKSLKQGDVFTDSIIESFKIGAIDKWQKKLKTRIIEAGIQKIRSIVKIHTKENMDALD
                     EVVWNSISDLKFNIMKDTLTRESLFTRVREAIENKDYQTASDLQIELKRSMEEIQQLY
                     MQYKKNIY"
     gene            53840..54616
                     /locus_tag="PC466_000684"
     CDS             53840..54616
                     /locus_tag="PC466_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HDF2768107.1"
                     /translation="MEYIIFDLEFNQGFDKKLNKTVSNEKCPFEIIQIGAIKLDSKFN
                     IIDTFNSYVKPTIYKDIHPFISRMTNIKNSDFNDSPTFPEVYNNFIKFISSQDPILCV
                     WGVGDLKELYRNINYHKLPSSSLPKSYINIQQHASKYFNNPAGKSIGLQNAISILELD
                     EKMSYHNALNDAYYTAKVFIKIYNPSIVPDIYLYTSIKPKTIRYSNKKRVDYDKLFDE
                     FRKILNRELTKDEKKIINLAYNMGKTNQFTLENVKQRKNK"
     gene            complement(54708..55460)
                     /gene="xth"
                     /locus_tag="PC466_000685"
     CDS             complement(54708..55460)
                     /gene="xth"
                     /locus_tag="PC466_000685"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HDF2768108.1"
                     /translation="MKFISWNVNGIRACVGKGFLDFFKEVDADIFCLQETKLQEGQIE
                     LDLPGYFQYWNYAERKGYSGTAIFTKKEPLKVMYGINIEEHDKEGRVITLEFEDFYFV
                     TVYTPNSQSELKRLEYRTRWEDDFIDYLTKLDNHKPVIVCGDMNVAHKEIDLKNPKNN
                     MKNAGFTKEEREKFSKLLDSGFIDTYRYFNPDKEGVYSWWSYRFNARKNNAGWRIDYF
                     CASKKLEDRLVSADIHTEILGSDHCPVELEIK"
     gene            complement(55621..56571)
                     /gene="galT"
                     /locus_tag="PC466_000686"
     CDS             complement(55621..56571)
                     /gene="galT"
                     /locus_tag="PC466_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-1-phosphate uridylyltransferase"
                     /protein_id="HDF2768109.1"
                     /translation="MKELRIDPITNDVVIFATDRLKRPLDTADIPNEDEETNEYDEEC
                     PFCKGNEAHATDALFEIESEEGWLVKSVYNKFPIIDDMARDVYGVHEVMIESDKHNRS
                     FYNMSQKEFEDVFFMYRNRFRDLSKDDKVEYVSIFKNFLRKAGASLMHPHAQILSMSF
                     IPPEITNELLVSKEYYDSNKSSLYDDLIENEISLDRRVVYNGEAFLVLIPYATKYSGE
                     VRIIFKDKIEFGELNDNNIQELSTIFEKLFKKLYNINGYMPFNLCIHTHPTKIETKSY
                     FNVHMHIIPRKYNFGGFELGTNMYVSSMSPEDLTKKLKID"
     gene            56956..58152
                     /locus_tag="PC466_000687"
     CDS             56956..58152
                     /locus_tag="PC466_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HDF2768110.1"
                     /translation="MNYSNRVSAMQASPIRKLVPFAQAAKDKGIKVYHLNIGQPDIKT
                     PKGFFDAVKNFDSEVLEYATSEGIPELLEALQNYYKTYDMNFEKDELLVTNGGSEALL
                     FTMMAVCDPGDNLLVPEPFYTNYNGFGQSVNVEVNAVTTKAENGFHLPSKEEILSKVD
                     DKTKAIILSNPGNPTGAIYTKEELNILAEIAKEKDLWIIADEVYREFVYDGLEYTSCG
                     NLEGVQDRVIIIDSVSKRYSACGARIGSIACKNKGLIAQILKLCQGRLCVPTLEQIGA
                     VELYKTPVSYFKEVNEEYKKRRDVLYNELMKVEGVICKKPTGAFYIVAKLPVENAEDF
                     TIWMLKEFNKDNETVMVCPAEGFYATPGLGRDEIRLAYILNEKDLHRAATLLKEGLEQ
                     YVALQK"
     gene            complement(58264..59610)
                     /locus_tag="PC466_000688"
     CDS             complement(58264..59610)
                     /locus_tag="PC466_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HDF2768111.1"
                     /translation="MTMKKRYNIAIVGGGSTWTPGLLKSLCKMSDRFPLNKVTMLDVV
                     EERQRLIGEFGKILFKEEYPKATLEYTTNPDEAFIDVDFVFVQMRTGGLKMRELDEKI
                     PLQFGLVGQETCGAGGFAYGLRSIGDMIEMVKTVRKYSPKAWILNYTNPAAIVAEALK
                     RVFPDDKRLLNMCDQPVNLLRSYGRLLDMDSRTFEPVYFGLNHFGWFTHLYDKNGEDL
                     VPKIKDLVANSGFQPVDAEQRDKSWLDTYGMVKDMLEDVPDYLPNTYVQYYLYPDKKV
                     AKSNINCTRAREVMNGREKRVFEECKSVIEKGTSIGSNLVHNDAHGEFIVEVAEAIAH
                     NKHQIAIVITENNGAINNLPDDAMVEVAAILTKNGPRPLHVGNIPTFYKGLLEGQLAY
                     EKLAVDAYFEQSYEKAILSLTLNRTIISPTKARQVLDALIKVNKDYWPTLYKENEK"
     gene            complement(59743..60495)
                     /locus_tag="PC466_000689"
     CDS             complement(59743..60495)
                     /locus_tag="PC466_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDF2768112.1"
                     /translation="MNLIDKLDINQKKLSTNEISLLNYFLKNSEKINQKKIKDIANET
                     FNSTAYIVRFCQKLGFSGYSEFKNFLVFSYSNRNERNKEFTKSQSDIFTDVMDTQNLI
                     NVENIDMCLNEIHNSKHIYFFGVGSSRLVCTEMSQRFSAIGVNVKYYDDSTLMYLAAS
                     NITKDDLVIAVSMSGETAQVIKACNIAKTNQVKVISLTNISVNSLSNIADIKLFVSSP
                     QYNFNSVNYTSRVPALSLMEYMFHKYIEKYNR"
     gene            complement(60654..62231)
                     /locus_tag="PC466_000690"
     CDS             complement(60654..62231)
                     /locus_tag="PC466_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDF2768113.1"
                     /translation="MKQKMKEFFLQLGKSFLLPIALISAAGIFLGISSAFSNPNIVSD
                     IPFLENNFIQGILGFTKAITGVLFGNLAIFFAISISVGLAKEEKAVSAFSGFVGYLVL
                     HTSVNYMLGCRGILAEPDMMREMGQAVTLGIQTLELGVFGGIVVGIITASLHNKYYNI
                     KLPDYLGFFGGTRFVPIITTVVFSILGIIIPYIWPYVNTIIQSVGIGIASLGYLGTFV
                     FGFLERLLIPFGLHHILNAMFRFTEVGGSLVVGGQEVFGALNIFLAQLSDPETISFST
                     EATRFLAQGKIPIMVFGLPAAAYAMYKTAKPENRSKVKGILLAGALATFVTGITEPLE
                     FSFLFVSPILFVIHAFLSGISFMMMHIFGVAIGNTQGGIIDLVVFGVMQPNTKWIYSI
                     ILGLVYALVYYNVFKVLILRFNLQTPGREEITDINFDLEPLSNKVEIAQSGETTKRAL
                     SIIKYLGGKENIEDITNCITRLRVVVKDMSKVDENAFKKYTGAMGVIKVSDKDIQIIY
                     GPSVSQVRDEVSFAMSI"
     gene            complement(62644..63096)
                     /locus_tag="PC466_000691"
     CDS             complement(62644..63096)
                     /locus_tag="PC466_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF2768114.1"
                     /translation="MNYIVKDTISFLVKTFPKIYSSLYLEDLKKFAPDYNVNKTQLRA
                     LVFIKNYGVISMTDLCSKLNIEKGSLTSMVDDLTDKKYVTRKRDLVDRRKYLIDITEE
                     GDKIATDFMDKLSDGLGEKLSKLTEEDRKKYLEAINTLQYILNKEEFR"
     gene            complement(63407..64852)
                     /locus_tag="PC466_000692"
     CDS             complement(63407..64852)
                     /locus_tag="PC466_000692"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HDF2768115.1"
                     /translation="MIDNKYTTYSNPLTDRYCSKDMSYIFSPQFKFSTWRRLWVALAE
                     GEHELGINITEEQLDELRANIDNINFDEARKIEKEVRHDVMSHVKAYGLQCEKAKGII
                     HLGATSAYVGDNTDVIQMNEALKLLRVKLVNLINNLKEFALKYKDMPALGFTHFQAAQ
                     LTTVGKRACLWAQDLILDLEDLNYRIDNMKLRGVKGTTGTQASFLSLFEGDHEKVKEL
                     DKKICKKMGYHSSYAVSGQTYTRKLDYQVISILSGIAQSMHKMTNDIRLLQSLKELEE
                     PFEKNQIGSSAMAYKRNPMRSERIASLSKYIISESISPAMVQATQWLERTLDDSANKR
                     LAIPQAFMAADAILEIGINVTDGLVVYENMINKRVNEELPFMATETILMEAVKRGGDR
                     QELHEIIREYSMKAAYRVKHEGKDNNLIELIMNDDSFKMSKEEILSIMDPKNFIGRAP
                     EQVVEFVNEVVEPAIKDYKEDLGKVDVDLRV"
     gene            complement(64996..65904)
                     /locus_tag="PC466_000693"
     CDS             complement(64996..65904)
                     /locus_tag="PC466_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDF2768116.1"
                     /translation="MYSTKILDDYEYETFNVFSTKLNPNTKHDYLSKVILFKEFLKGK
                     ELIYATKEDCKNFVDYIQTKYAKSTCEKIYSYLHSFYNFLKKEGYIDINPFRYVEKPT
                     VTRIKTKDDVLSIQEINKLIGILPKLNIRDRVIIVCLVTTGCLLNELVSLKWKDLMVD
                     ENDNSYVRLGKGRKERVVKLHPYFFKLLEDYRNYSGLPEVIIPSDDFIFTTQKSNSIT
                     DRNVRLIVKKALDLAGLSQYSARDFRHSFAAISLRLGADESDVKNQLGWSDKYYAIRY
                     KYVLNFVDSEIVDYLIEKDNLDINKK"
     gene            66161..66985
                     /locus_tag="PC466_000694"
     CDS             66161..66985
                     /locus_tag="PC466_000694"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HDF2768117.1"
                     /translation="METFSLLEIFKAVILGIVQGITEWLPVSSTGHMILINEFIKLNF
                     SNTFINTFLVVIQFGSILAVLVIFFRKLNPFDSAKNIKQKKETVRLWLKVIIAVIPSG
                     VIGILFEDDIDRVFFNSTVVAIALIVYGIIMIGLEKRNKRPKYKDFSQVTYKLALCIG
                     LFQCLALIPGTSRSGSTIIGAVLLGTSRYVAAEFSFFLAIPTMLGASALKLLKAGFGF
                     TGFEWLILGVGSVVAFVVSIVVIKFFMDYIKKHDFKVFGYYRIVLGIVVLAYFFLL"
     gene            67025..67555
                     /gene="lepB"
                     /locus_tag="PC466_000695"
     CDS             67025..67555
                     /gene="lepB"
                     /locus_tag="PC466_000695"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HDF2768118.1"
                     /translation="MSVKKEIFDWIKSIAMAIVLAFVILQFIRPSVVSGESMYPTLDD
                     KDYLILNRISYKVGKPEKGDIVVFKTNLVDGETGKKKDLIKRVIATEGDRIKISNSKV
                     YVNGKLLNEPYIHNNYTSGDIDTVVPKGKLFAMGDNRENSNDSRFPDVGMVDEDEILG
                     KVMVRLLPLDNIGKVD"
     gene            complement(67637..69418)
                     /locus_tag="PC466_000696"
     CDS             complement(67637..69418)
                     /locus_tag="PC466_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UvrD-helicase domain-containing protein"
                     /protein_id="HDF2768119.1"
                     /translation="MSQYININSQLDALKLKEFEKIFYENINEDVKVVPKVTPFKGIN
                     TDLLYVKDGRILFIKFMDTTEDIFFILEEELLEVMNEEYELLKLKMGQKNRNISYNYV
                     YIMPYVEVEETYEFEEFVNNNIIDKNKLQDIMNKGSLEEYLNDENDEINLNLFLLDIC
                     SEYYIINDKLHLNEKFKKISFYNDDYKYTATMMEDVQIKDVVSIKYGNTLIEGGSGIG
                     KTAIMLSRAIKLAKVYPHHKLVIFTHTKQLCNELRERIELLYKDNNNLEVHTFSSFIF
                     KLAKKFNLIVDYNMLKNDYEKTFNNLVKQAQNIIKNKNMFKAIFIDEAESFLEYEIDF
                     IREFLYKTKFIFNVCSCNSLNISNRLNIFKKLYNGIEFDDKIILSKNYRQAKEIVDFT
                     NKFSNNSNSYINELRPNTEFSTFFYTKALRGGNKSVDIIKVSDLDDQISSVIWEIEYL
                     ISKKGLDYSEVAIVYPYNKKKLKSGKTIYFQYMLKKALEEAKIPYICAEDNLTNISKK
                     VGTTIANIYAIKNLEYKAVIVCELEMLYNQTINDIEQDYQVNDFVGDLNKVYLAMSRA
                     TDYLSIVTTFNEEASDIIRLITESKDI"
BASE COUNT        22958 a        11581 c         7886 g        27118 t
ORIGIN      
        1 tatagacttt ttttaattta ttatttagat ttttaataga tttcttaact atggaggtat
       61 ttaaaatatg gaaataaaga gatatgaagg aactggaaga atgagtagag ctgtagttca
      121 taacaataca gtttatttat gtggacaaac tcatgctgaa ggaggagtaa ttgaacaaac
      181 aactgaagtt ttagctaaaa tagaagattt attaaacaaa tatggttcag ataagcaaca
      241 tttgctatct gttactattt atttaagaga tatgaaagac tttgaagcta tgaactctgt
      301 ttgggatgct tgggttgaaa aaggatttga acctgctaga gcttgtgttg aagctagact
      361 tgctagagag catttgttag ttgaaatgag cgttgttgca gctacaaaat aatcaattta
      421 gcttatagga ggctatctca aaacagagag ataagcctct ttttcattgt tgaaatgatg
      481 aaaatatatt tgatttcgta taaaagaaag tgtctcacga actaaaaaat tcattttgag
      541 acacctcctc actatttaat ctatataaat ttacttattt tctattggca atatcaattt
      601 agatggatat ttacctccat ggtaaatcgt attctttgct tctatatatt caatactatt
      661 atatccctct ttcgtgttgc tattttggaa aataaagttt ttagcactag acgttatatc
      721 tagtctaatt ttatgaccaa ctttaaacgt gtttgatatt tttgaagtta taatcgtaaa
      781 cttataaatc tctccttctt ccataaactc tgacttataa aaactatttc taaatctagc
      841 actaagtata ccatcagcta atttaattga atttccatct aaatccacgt ccataatttt
      901 tataacccag tcagtatctt tggcagaact tgatgcaaaa aactctaact ttatatcacc
      961 tgttacagta aattcttcac taaaagcatc tgatgtataa cacaacatat cacttctttt
     1021 ttctaaatct ttgtagttat ttggaactcc aacttcattc tctgacatat caattagttg
     1081 tactgatggg tcttttggat tatatatata actatcatac ttttcttcta aatcattatc
     1141 aaatactaat ctaccatttc ctaaagatgt gttagcattt ccatcactta ttagatacat
     1201 acttttatct atcttattta ttattggcca attttcttct gtcttccact tattaaaacc
     1261 tacagagtaa tactctactg gagcagtcgt atctatgtta ttttctatac cttttaagta
     1321 tttatcaaac cataatagat aattataatc caaatcatat cttaatgaac tatttcctaa
     1381 agaaatacca tttatatctc ttaaagtatt tgaattatgc atccatggac ctagaatagc
     1441 ctttctcttt cctttttcat agtcctttat aacatctaag gcctctgtag ttcccatact
     1501 attatcatca taccacccag atacaaccaa tgcaggtaca tttattttat ctttttgtaa
     1561 atgccaatcc atcaaatccc aatactcatc tttttctact ctctttaacc attcttccag
     1621 aaattcaatt ctatatccaa gagcttcaac aggtatattt tctattggtc gtatgtttaa
     1681 aacatcatcc caatcatctc ttaccatttt acttctatca actttatttc ttgataccat
     1741 aaatgcccat gcaagcatac cagatacaaa agctcctcct tttcttggta tatcaataaa
     1801 agggcttcct gatgttacta tactaactaa agctttaaga tgcttattgc ctgaagatgc
     1861 agctgcccat tggacataac caagatatga tgctccaagc attccaacta ttccacttga
     1921 ccattcctgt gatactatcc aatttatggt actatctcca tcttccctct catgaatcat
     1981 aggttcccac ttaccttctg attcatttct tcccctaaca tcttgtatta caacagcata
     2041 tcctctttgt acatatttat aatatatttc tttatcattt tcttttccat atggagttct
     2101 cataagaatt gttggtgctt ttttggtaga atctacaaaa tcagggagat atacatctgt
     2161 agaaaatttt ataccatctt tcatatcaat catataattt ccaccaaatc ttatagaata
     2221 tatctcttca tttttatggg ttttttccca ttcttttaat acagtatact cttcatatcc
     2281 atccataatt aatatagtac aagtttctct ggataaacag ataaaaccta ctattttatt
     2341 atctacaata attatatcta gtgggaactt tttgtttctt tgaacccata tatattcatt
     2401 aagtttagaa tgcgtttctc ctaagttatt tataactgtg tctttatctg tgtttactaa
     2461 gcttttagta tatacatcaa agttattaaa taaagacttt aaatctattt ttgtaagatt
     2521 taaatagtat gtattttctt ctttgcttat tggttttaaa ctttctattt tatttgtaaa
     2581 aggattcaac ttttcaatta ataaatcgcc atcaaagatt acatttccac tgtatagtcc
     2641 agatatgtat aatttaaatt ttatcaatta aactcccccc tataatccta gagacatctt
     2701 tattgcatat gccactgata tacctgcata atttcctaat actccaccaa ttactcccat
     2761 tacgactgct acacttacaa gcgaattcca ctttgcagaa gcagctacta aagctgaagt
     2821 aggaccatca gcaattgctc ctactataga aagtattaca tattgatact ttatctttaa
     2881 aagtctagtt atgcctaaat gaaaaacaaa tgaagcaaaa attatgctaa aacagtaaag
     2941 tgttatagta aaagttgaac ctaaaaactc ttttatatct actgaaaaac ctattgtaca
     3001 taaaaagaat aatgcaacaa ataatcctaa atctaaattt ccctttagtt tctttactgg
     3061 ctttaattga gcaattataa ttgaaattgt tgtaactaaa agtattcttg ctgcactact
     3121 aaaacttgaa ttgaaatatc cagcaagtat tgttgaaact tctgtaacaa caaaacctat
     3181 agccaacatc caagctatat ctttaatact ccattctttt gactccataa attcttcatt
     3241 ttgacaatct tctaattctg tttcttctac atgatatggc caaagttttt taaacttctt
     3301 tgaatttttt aatattgctg gtagagcaaa cataaatatc aatgttggta ctccaattac
     3361 atagtctgct gcatttgctg cagcaagagt ttgtctactt acattaaggc ctgttccaat
     3421 agctgtaaga ttagcacttc caccagtgta tgtacctaca aacattccag caaccttcca
     3481 accttctgat attttttctg caaatactaa tccaaataaa aatgccatga tacttacagt
     3541 taatacagct acaaaaattg caattaaagg ttctcttgat aattttgtca tttcttttaa
     3601 gtcaacactc atcaacatta tagtcataga aactgggata gcatatgttg aaatagttcc
     3661 atataactca gtacttactg gaactacttt taagtttgaa agtattattc ccattatgat
     3721 tattgtaagt gctggtccta agcttttaat ggctttgtat ctttgtaagt aaaaacccaa
     3781 tgcaatcatt gatgtcatta cagcaagtat actacctgga tttgaaaaaa gtgtattcat
     3841 atttaacctc caaatttatc ataagtttac ttctattcct aaacctggtt tattgacaag
     3901 attcataata tctccatcca ttacaaatcc tccagatata tcttttgatt cttcacaaaa
     3961 cataaaacta tcaaggtcag cttctgttat gttcttttta gatgctatta aatttgctgc
     4021 tgctgttata ccaattctcg tttccagcat acatcctaac atacaattta ctccacttgc
     4081 ctcagctatg ttgttgattt ttatagcagg atatattcca cttgatttca tcagcttaat
     4141 attaaatgta tcaactgcat tcttttttat agccttaatt gcatctattg gtgaatgtaa
     4201 cgattcatct atcataattt ttgtattact tttatttctt atgtaagcag taccatctaa
     4261 atcccaatgt ggaagtgctt gttcaattgc atcaacatta aattcttcta attttttgat
     4321 agtatttata ctgctattta cgttccatcc ttgatttgca tcaattctaa ttcttatact
     4381 ctctccaacg gcttctctaa ttaattttac agcttcaata tcgtcttcag gatttatacc
     4441 tgctttaagc ttcaatatcc taaaaccttc ttttactctt tctaaagctt ctactgccat
     4501 tttttctggc ttatctatac ttatagtaat atccgtttgg actttactat caaatcctcc
     4561 aagaacttta taaagaggtg cattcataat ttttccttta atatcatata aagctatgtc
     4621 aatagctgct tttgcagaag tattacctat aataattcca tccatgattg tatgtatggt
     4681 ttcaatatct agtgggtctt tgcctattaa ctctttttta aacataagca atactgaaag
     4741 aacattatcc aaaacttcac ctgtaactgc tgcaagaggt gctgcttcgc caaatccaca
     4801 atacccttca tcagtttcaa tttttaaaat tacactttct ccatattcaa ttactccaaa
     4861 tgaaactact acaggttttt ttaatttaat tctaagcttt tcaaatttga tatctgttat
     4921 cttcatatta ccctccttat tttttgaagt tataattcaa tttttaaaat tttatacttt
     4981 aaattatatt attacttcaa tatatatgtc aagataattt actgaaaatt tactcttttc
     5041 caaaatataa tgtgataatc ttaattcaat taatactctt ctattaaatt tttttattat
     5101 tattttcttt atattaattt aacaataatt cattttcata gacttttatt tggatttaat
     5161 taaattttaa ttgtcaaaat ctactatgta ttcttattgc cactacttct atgttgtgct
     5221 ataattactt tgttttaagc gaatatttta tattaatttt attatttgga ggttcttatg
     5281 ctaggtgaaa agatgagaaa tataagaaaa agcaagaaaa aaacattaag tgatgtttcc
     5341 aaattgacag atttatctat aagttatatc tctcaaatag aaagagatgc tattgaacca
     5401 tccttgtctt cattgagaaa aatcgctgaa gttttagaca ctcctttata tatgtttatg
     5461 gatgacaata atactgatga tttagtaatt agaaaagaag atagagttat gatgaaattt
     5521 ccaaagagtg aaatgtttta cgagatagta tctccaatgc ctacaactga atttacacct
     5581 tcaattttat ttgtagagtt tgaacttaaa ccagaaagtg aggatgctaa agattatatc
     5641 tatcatgcat cagaagaaat tatggtggta acgagtggtg tggttgatat ttgtatgggt
     5701 gaaaaggtag ttagattaaa tccaggtgac tcaacattta taaaagctaa tgtaccacat
     5761 aaaatcatca atccaagtaa agatacaata gctcgtggat atggagttat atcacctcca
     5821 atttggccaa taaaatctaa ataaactcaa cataacacac ctactttttg tagataatat
     5881 aataaattta aatattgctt ttattttaaa attgaagtat ttatttaaat ttaaaatatt
     5941 tactcaaact aaaaaaatag ctatttgact aatctaaacc atcttaatta tggtaaatag
     6001 taaatagcta tttgtaagtt atattataaa ttataataaa aattgtattt gttaaaatta
     6061 aattaaactg ctatatcatt taatactttt gcctttacaa ctcttatatt tttcatactc
     6121 ttgtagatat cttgaatctt atcttcttgc tctctcaata gtctatgtgc ttcatatata
     6181 tctacaagtt caaattttac tacatcattt ggctttgctt gtgctaactt atacaaatct
     6241 acacttataa cgttccctat cttagtatag ccaccactag tctgtctatc tgataacatt
     6301 ataatcggtt ttccatgacc aggtacttgt atagctccat aagaaatacc atcagatata
     6361 atatctgctc cattaaggtg ctttatactc tctccatcta gtctacaacc cattctatct
     6421 atttcattcg taactttgta tttatttgat aaaaatttct ctacttcacc gttagaaaaa
     6481 gcatcaaatt gaggaccttt tacaattctt agtacgattt ctgaactata agttggaata
     6541 tattttgaat ttaatttttt atttattgta aaatcttttt cctgaataaa agtatttata
     6601 taatctcctt ttttaagtgc tctaccttca aatccgccaa ttttagatct tgtataagtt
     6661 gacttacttc ccattgcaag tggaacatct attccaccag ctattgacac ataggctcta
     6721 gcacctgatt tcacacctct aaatgataat acatcacctg gatttatttg atatgacctc
     6781 cagttttgaa tttcttttcc atttatttta gcccctaaat ctcccccagt tactgctatt
     6841 tgcgtatatt catcaaaggt aattgtagga cctaacatta aaacttctaa agaagcctca
     6901 tcttcagaat ttcctactaa tatatttcct actctatgtg catactcatc cattgctcca
     6961 catccagata caccatattg accatagcca actctacctc tgtcttgtat taatgtttgg
     7021 aaacctccta attcaacttt gaatcccata tataccactc cctgtactat aacgatattt
     7081 aaatacttaa gttatttttt tcgatttcta taaattcatc taatgttatt ggaacaaatt
     7141 ttataaagtc tccagctcta agcaaaatct gttcttctct attttcatca tataatttta
     7201 aaggtgtcct accaattatt tgccatccac caggactatc aataggatat acaccagtct
     7261 gggaacctgc tattccaaca ctcccaccat aaattttagt ccttggcact tctaatctag
     7321 gtgtagctat tctttcatcc ataccaccta gatatggaaa tccaggagta aaccctagca
     7381 tatatatcaa gtactctctg cttgtgtgta tttttataac ttcatctaca gtgagattat
     7441 tgtagcttgc aacgttttta atatctatac caaaaacctc atcataacat actggaatct
     7501 catgtatttt aggttttggt aatactatac tttccaaatt atcttctatt ttttttaaat
     7561 tctcaatcaa actatcaaaa tctatttcta atggattata acttatcata agtgacctat
     7621 atgttggtac catttctgtt acaatacctt taagattcga tatttctatt gctctcataa
     7681 atgaaattac ttttttgttt atatcttctg atatctcatt tccaaattca gcaaccactg
     7741 ccttatcccc tgatatcaag tatctagttt ccataaatgt cacctcttct aaattaagca
     7801 aataaagcac ctaggctgct aagagaagtt attcctgtat atgcagatat taaaactact
     7861 attaatccaa atattaaaag ccatgtagga tgcttgtaat ctccaacaat atcttttctt
     7921 ttagatgcta taagcataat tcctaatgtg attggaagta tcaatccatt taaagctcct
     7981 gctaaaatta ataaagtagc tggttttcct ataaatgcca ttataagtgt tgatattgct
     8041 ataaatgcta ttataaaata tttttcatat ttatctataa aaggatttag tgtctttaag
     8101 aaagaaactg atgtataagc agctcctata actgatgtaa ttgcagcaga ccataataca
     8161 agtccaaaga atttatatcc tattgctcct gcactaaatt taaaagctga agcagctgga
     8221 ttttctgggt caagttgaag accttttgaa accactgcca gtattgctaa aaataaaaga
     8281 actctcatca ttgtgtcaac taatataccc aaaagagaag atttagttat ttcttttata
     8341 ttttcttctc ctgttattcc accgtctatt aatctatgtc ctccagcaaa agttatataa
     8401 cctccaacac ttcctccaag tagagttatt attgggaata tcaatccttt tggattttct
     8461 ggttttacca ttcttgatac tgcctctcca acaggaggat gatttgatat tgctacatat
     8521 ccaactataa ttatcattcc taatgctaaa aatttagtta tcttatcgac tagagaattt
     8581 gaattttttg acataaatac aaatatagct attaatccac ttaatacagt tcctaatgtc
     8641 atattcatat taaacattac attcatacca agtgcagctc caccaacatt tcctatatta
     8701 aaagctaatc ctccaagagc tactaaaaaa gctactaaat aacctaatcc cggtattatt
     8761 ttatttgcta tatcctgacc tctaagtcct gatacaccaa ttactctcca tacatttact
     8821 tgagccccta taaaaaggat tgttgtaatt aaaattacaa atgaaaaatt tggtccaaaa
     8881 tcttgggtaa attgtgcagt ctgagttaaa aaccctggtc caattgctga tgttgccatt
     8941 ataaatgcag cccctataag tgctccgaca tcttttttat ttttagtttt atctgtaata
     9001 ttttttgtac tcatatttta tctccccctc atgttatcag tcttatacta tgttctctga
     9061 cgaacaaact tctatgtttt ctaatggaca aacttctata ccttctaatt caaaacgctt
     9121 tcttatttct ttgacaaact ctattgcttt tggattgtcc ccatgtacac atatagaatc
     9181 tgctttgata tgtataactt cacctgttaa agtttctaca gttccttctt ttaccatcct
     9241 aacaacccta tctattgcat gttttgtatc atgtataact gctccttcta cacttcttgg
     9301 aaccaaaaaa ccattattat cataagctct atctgcaaat acttcatttg caaacctaag
     9361 tccaatttct ttagcagaat ttatcatttc actattatat agccccaaca gtataatatc
     9421 tttatcgact tcatatatag cttcacaaat ccccatagct aactctttat ctttagctgc
     9481 catattgtat aatgctccat gtggttttac atgttgtata ttacatccat ttgaacttgc
     9541 aaatgccatt aaagcaccca attgatattt tgtataatct ttagcttcct gctttgttat
     9601 tttcatctca cgtcttccaa atcctattaa atctaggaaa cctggatgtg cgcctatttt
     9661 cactccattt tttttagcta gctgtactgt tttttccata tgactagggt cacctgcatg
     9721 aaacccacaa gctatattag ctgatgaaat atattttaaa acttcttcat ctaaaccaat
     9781 cttatacgtt ccaaaacttt ctcctaaatc actatttaaa tctactttat acaatttatg
     9841 accccctcct tgctaacatt ttgatagaat aagtagtttt aatttttaaa ttttgtttat
     9901 tttatatatt gcatgaaata ttttatcact tgtattcaat tttatttttg caactattct
     9961 attgcattta attaatataa ttttaccatt taaggaatat ttttgcaatt attttaattg
    10021 aacattcatt tgtatttctt tttcaaaaaa tctttttacc attttttagt taataattaa
    10081 ttattttcac ttaaaataag ggccttaacc ttcattttta aagtattttt catttttaat
    10141 cactttatat gcaagacaga atcatttttc ttcatttatt tgtttctttc atctatataa
    10201 ttatcattct ttgtaagtaa aatatcttta tatttttata attaattctt tatatagttt
    10261 taagtataat aaaatcatgt atactaaatg catgttaaaa tattatttta aaacatgcac
    10321 aatatttgta catattgtag acatataaac ctataaatta tacaatagta ttgttaagat
    10381 tatatatttt tttaacataa attttgtatt gggggaaaaa caatggataa aaactatacg
    10441 atgccaatat accaaaaaat agcgttggat attgcaaata aaatatacac gggtgaaata
    10501 caagaggatt cagtactatt tggacgctct gttttggctg gtaaatacaa tgtatctcca
    10561 gaaacgataa gaagagctgt caaaatttta gaggacattg gcgttgttaa aagcataaag
    10621 ggtaaaggtg ttattgtact atctccagac aaagcttctt cttttataaa aaaatataga
    10681 gatattacaa atatatcatc atataaatca acactttata atttaataga tactaaatct
    10741 aatttagaaa atgaaatatt agatactata aataaaattt tagactattc caacagactt
    10801 gaaataatca atcctttagt gcccgttcag ttcaccataa attctaattg caaatatatt
    10861 ggtcaaacag ctgcacaaac taaattttgg caaaatacag gtgctacaat agttgcaatt
    10921 aaaagaggtg aagaacttat aatatctcct ggaccatata ttgaattttt agaaggagac
    10981 attctcttag tagttggtga ccaacacatt tacaattcta taccaatgtt tttatatgaa
    11041 aacgaaaaat aaattatata atttagtatg attatataaa aatgcaaaat taacaacaaa
    11101 aaaagagctt catattttac ataaagctct ttttaaattc aaataaattt aactttgatt
    11161 aatttttaaa tatccaattc atcttctttt tcccagctta aagctctcga tacagctttt
    11221 ttccatcctt tatataattt acatctcttc tcttcactca tatttggatt aaactctttt
    11281 tctactgacc actttgaagt aatttcattt cttccaatat agaatccaac agacaaccct
    11341 gctaaataag cagctcctaa agctgtagtt tctactattt tgggtctatc tatatctaca
    11401 tttaatatat ctgattgaaa ttgcattaaa aaattattat tacttgctcc accatcaact
    11461 tttaatgatt ttagttttaa ttttgaatcg ttttgcattg cttctaaaac atcctttgtc
    11521 tgataagcaa ttgattccaa tgtggctctt actatatgtt ctttttttgc tcctcttgta
    11581 agtcctaaaa ttgaacccct agcatacata tcccaatatg gagctccaag acctgtaaat
    11641 gctggcacta catatacacc attagtatcc tctaccctat ttgcatacat ttcactatct
    11701 tttgcagatt caattatctt taattcatct ctaagccatt gaacagatgc tcctccaata
    11761 aatatacttc cttctaatgc atatgttact tttccatcaa ctccccaagc aattgttgta
    11821 agtaacccat gcttagattt aactatgtta ctgcctgtat tcataagtaa gaaacaaccc
    11881 gttccataag tattttttgc agtaccttct tcaacacaat tttgaccaaa taatgctgct
    11941 tgttggtctc cagcacatcc tgcaataggt attttagctc ctgataacat gcgctcatct
    12001 gtatgaccat aaacatagct agaaggtttt actaatggca acatgcttat tggtatgtcc
    12061 aattctcgta atatatcctc atcccattct aaatcattta tattgtacat cattgttcta
    12121 gatgcatttg agtaatctgt tacatgtact ttcccacgag ttaaattcca tattaaccat
    12181 gtatctatag ttccaaataa taactctcct tgttctgctt tttccctagc tccttctaca
    12241 ttatctaata tccattttac ttttgttgct gaaaagtatg catctattaa aagacctgtt
    12301 ttttctttta ttgattcttc caatccttta tttttaagtt catcacatat ttctgatgtt
    12361 ctcctacact gccatactat tgcgttataa ataggtttac cagtatacct actccaaaca
    12421 accgtagtct ctctttgatt agttatccct attgaagcaa tttcttctgg tcttatacct
    12481 gctgtttcta taacttctct cattacacca ctttgtgacc cccatatttc catagggtca
    12541 tgctctaccc atccagcttt tggataaatt tgattgaact ctttttgtgc aattttcact
    12601 atttcgcctt ttttattaaa tagtatagct cttgaactgg ttgttccttg gtctaatgcc
    12661 attacatact tcttttccat caccatattc tccttatcat ataatattta atttattaaa
    12721 aagaaaaatt taatatcaca tatttcaata aataatcata cttaagtaca aatttaatat
    12781 aatagatatt tataaaaaga cacttatttt ctatcatatc tatataataa tattatacat
    12841 tatagcttac atattgatta ataaatttta aaggagtata ataaacagtg ttcataataa
    12901 ttttaataaa agaggtggta atatgccaaa gattttagaa aatgtaaaag aagatatatt
    12961 aaaagtatct cgggatatga ttttagaaga agattactcg aatattagca taaggaaaat
    13021 agctcaaagg tgtggtataa gtgcaggtac agtatataat tactttaatt caaaacaaga
    13081 aataatagaa tatatcacaa aatctgaatg ggatttattg ataaggcgaa ttgaatactc
    13141 caataaaaac actgaagatt acataaaaaa actaaacatt atttttactg aaataagaaa
    13201 ttttataaac aaagttcata atatccaata caatgacttt ttaaacactt ttgaaacaga
    13261 gagatttttt gaaatgaaaa aacacaaaga cgactttcat gaacagcttt caaataaagt
    13321 atatgaagct ttagaaaaag aaagtttttt taataatgac aaattagtat gcaatatcat
    13381 aataaaaatg tttttttcat attcaacata tcttcatata gaatttgaag atttaaaacc
    13441 ctatattgaa aaattaatac attaaggtgg tgtttacctt gaatcataat actagtatta
    13501 agaacaagga cagtaatcca aaaatatttt tagtacttac actttatcta ttaggtatat
    13561 ttatgggagc tattgatact ggaatagtat caccagcaag aacgattata caaaatagcc
    13621 ttggagtaaa tgaaaaaacg ggaatttgga tgattaccat atacacatta acatacgctt
    13681 ctgtaattcc tatctctgga aaattagcag ataaaatagg aagaaaatat gtgtatctag
    13741 ttagtatatt tctatttggt agtggttcat taatatgtgg attatcatca ctattttcca
    13801 atttctatat tttattaatt ggtcgtgtta ttcaagcaat tggtggtggt ggaatcatgc
    13861 caattgctac agcagaattt ggaactacct tcccagaaaa taaaagaggc atggctttag
    13921 gtttagttgg ggcaacatat ggtattgcca atattttagg ttcaagcatt ggtagcacaa
    13981 ttctaagtat ctttggaact caaaattgga agtggctatt ttttgtaaac cttccaattt
    14041 gtttaatcat acttattggt ggagttttct gtattaaaaa caataagtct gaatctaaag
    14101 aaaaaataga taagcttggt acattgatgt tgatatgtat aatcgtatca ctattatatg
    14161 gtcttatgaa tatagacttt tttaatttta aaaattctat acaagatata tcagtttatc
    14221 catacttatt gacatttatt gtacttatac ctattttcat atttattgaa aatagagcta
    14281 aagaccctat tttaagcttt gaatattttt taaatccgag aatattgata gtacttattt
    14341 tatctttaat tgttggtatt ggaatgatgg gtatggtatt cgttccacag tatgctgaaa
    14401 atgcattaaa gataaatgct ggttctggtg gatattttgt agctatattg ggattatttg
    14461 caggtattgc tgctccttta agcggaagac ttattgacaa gtttggggca aagaaaatac
    14521 tattactagg attttctgta tctatgatag gctctcttta cctagtttta attgctctaa
    14581 aaaccaatac tgtatttagt gtatgtgtaa gtttaatatt tatgggatta ggaatgggct
    14641 ttactatggg aactcctcta aactatatga tgttatcaaa tacaagatta gaagaatcta
    14701 attcagcact tgcaacatta tccttgatac gctcaattgg tacttcaatt tctccagcta
    14761 taatgattgg atttatagca catgcaggat tatctgtgca agataatatt atggacttag
    14821 ttggaaagcc ctcaactcct aaaatagttc aacttgaaga acttgaaaac atgatagatg
    14881 acttaaaatc agaccctgaa atggcaaaaa atttaaaaaa tgtctctatc ccaaatatga
    14941 atgatacttc aaatataaat atggacatga caggtggcaa acttccaaaa tccttactta
    15001 ataaagttca gtcagcagat acaaccaaca ttaccaatat aacaaaagaa atatcaacaa
    15061 caatgtttga tgaaaaagtt ccatctataa ttactaaaat acagaaaaat gtacaaaaag
    15121 gaatagatgg aacacaaagt ggaataaacg gtattgaaga tggtgaaaat aaactaaata
    15181 gtggtattaa aggagttcaa actggtattg acaatatggt aaaagctaga gctggtatta
    15241 atcaaggaat agatggtgta aaaaaaggta ttgctggtgt tgacaaaggt ataaaaggta
    15301 tggaacaagg tcttgaaaaa caagatgagg ccatcaagga acttacaact gcttataata
    15361 aaatacctac tacagaaaag actcctactg ataacgaaaa taactcaaat gaacaaaacc
    15421 agagtaatac cagtaattct gaatcagacg acactaagaa tgattctaca gaaaataaga
    15481 ataacaattc cagcgagaat aaaccaaatg taaatgaaca aaaagaaagt ttaaatgctc
    15541 aaatacagca actaaaaaag acaagagatg acttaaatac aaagttacaa aaaaataaaa
    15601 ctcaaaagaa cgaattaagt aaaaaactaa gatcaatgga atctcaaaag aaagagctac
    15661 aaagcaagtt aaataattct ataaaccaaa agaaagacat ggaaaaaagc cttgatacaa
    15721 tgcaacagca aaaaaaatca ctccaagcag ttttagcaaa gacacaagag gtaaaaactg
    15781 aaataccaaa ggcttttgat aaatcaaaat tggattatat aaattccata gaaaataata
    15841 gaacaaaaat agaaaataca ctacaatcta ctctaaactc aggattcaaa cagatgtata
    15901 taacagtatt ctgtgtaaat ctactagcat ttataatatt attgttctat aaagaaaata
    15961 aaactagata aaagagtgtt atagtattat attgtaaatt tatcttattc ttaaatattt
    16021 taccctaaag aataaattca taaaatcttt gtaattgatt aatataaatt acaatataat
    16081 actattttta tcttaatctt tttctctttt acagacaatc aaaaagcaat cttagtttat
    16141 cgaaataaat ttatacaatc tattcataca cccctttaca tttttataac aattaaatct
    16201 attgttatat atacaaatca aaataaacca tatattttca actataatat gttaaaatca
    16261 tattatgagc atattaattt aagcaaaatg tcatttagac tttaatttag tagttttata
    16321 ttataaattt atatattttt aatttcaaat gtcatttaga cattactcat aaaaagaaag
    16381 gagtgtattt tgtggatact ttaggaaaaa gaattgctta tttgagaaac tccaaaaaac
    16441 ttactcagcg caaacttatg gatattttaa aatttgaaaa cttaggcaag tatgaaacag
    16501 gagatagaaa acctaattgt gatatactaa tgtcaatagc tgattatttt aatgttacga
    16561 ctgactggct tctctatggt aaagagaagg taaatgtcaa tagtagtgta aaagaagata
    16621 aagaagatta cttacatgtt actaatgatg aaatgatgat attaaatcta tacagacaac
    16681 taaacgaacg tgataaaata aaaatagaag gaatacttga acttaagata tctgaatata
    16741 aagacttaaa aaagcattcc tctaataata atgaagataa aatggtttaa acatacataa
    16801 tttgatacga ttttacatca tctattaacc ttcttttttt gtagtatatt actaaaatat
    16861 ggatattgga ttatttaaaa acaagtatag tctaatttca agcacattta taatatttag
    16921 attatcttat ccatatttta gtttaagtac tttgaaaaat ataatacatt tctatgtata
    16981 atttatattc ctaagaaatg cattactcat gtttttaatt cttccaacat ctttctatac
    17041 acaattgtac atccttcata attcccctct ttaagaagga ttgaacatgt actagaatat
    17101 ttagttaaag tatttaatct ttccatattt aagcttttta tattactaag tgctgtaata
    17161 aaatcatcaa ttgctctaca acactctata accccatctg aatccaattt gcacacaaga
    17221 atattcacct actttatata ctatttatta atcatcttct gaatattcta tattaagtaa
    17281 ttgataaatt gatgatttat attttttacc tgttcttctt ccatttaaaa tagctgacaa
    17341 atagttttca ttaacaccta ttttcttcgc taattccctt tgagtcatat ttaattcaat
    17401 aagtctttgc ttgacttgca ctcccaaaaa aggtatccat ttttttcgag catccattta
    17461 tcaacttcct ttctaagtga tttatattta cttttatatt actttagctt acgcaccccc
    17521 tctatttagt atatattttt aatatgtaca catattaagt atataaattt atttaatact
    17581 aaataagatt ttttgattac tttgtgctaa aattaggatg taaattcgta tcattaagtt
    17641 aattataaag tcattttgac cttaagtcaa tggtttttat gtcattttga cctttaattt
    17701 gaaactattt acatcttaaa aagtcttttt gacattaatt gaatggagag tgtttatgga
    17761 tactttagga gaaagaattg tttatttgag aaaagcaaaa aaccttaaac aatatgaact
    17821 agaagaaatg ttaggctgtg acaacttaag taaatttgag agaaacatta gaaaaccaaa
    17881 ttatgaaata ttaaaatcta tagctgagat atttaatgtt tcagtagact ggctattaaa
    17941 tggagataat ctatcacata aatcagattt aatttgcgat tcctcctcaa actatccact
    18001 taatagcata aactctaatg aaataaagct tttaaacaac tttagaaagt taaatgatta
    18061 tgataaagcc aaaatagaag gtatgattga attaaaactt catgaatatg aaaaagagaa
    18121 ggatttagga aaaattgagt ataacaaaaa taaagatgag aaaatagata aataattttt
    18181 atgttgcttt tgatacgatt ttacatcatt tctttgttct aatattttta tttcatttat
    18241 tttctttttt ataattttat gataaaataa ttagtatatt ttgctttact tgaatgtaat
    18301 tatttataca aaagtcaaac ataatataaa tgtagtaaat ttttagtttc aagtaatatc
    18361 tcgttattat aactaaatat ttattaaaat taggaggata aaatgggctt aagagacaaa
    18421 ttcgcgcaat catttgctag atcaaaaact atgagtggcc ctgagaaaaa ggctaatgaa
    18481 ataatgggta aattgcttct taagaaagct atattaccta tcgttttaat gttcgtgata
    18541 ataatcgctg gagctatgct taaaatcaat tcttgggtta cacttggcat aaatttagtt
    18601 attgctgttg gtgctttctt ctacataaga aattctagta aaaagtatca gaactttaaa
    18661 ccttatgttg gcaatttgat tagtttagag aaaaaaggta aaaaagagta cgttgctatt
    18721 ataaaacaag gtaagttacc agttaagtta caaatagctt atggtggtga agaccttgaa
    18781 catgttaaga aaaatcaaat ggttcagata agttataatc cagatgctaa aatagctatt
    18841 ttggttaata gacaataatt taataaaaaa aaggagttgt cttaaaattg attttttcta
    18901 atcaaattta agcttaactc ctttttgaat ttttatatgt tatttttata tattattttt
    18961 attacttttt ttaattaata ttttaaaata taaaatcctt ctcaataaaa tagggcacta
    19021 tctacaatac tactttatct tttcctaata atatataatc tggtgctact gctactttca
    19081 tgttatacac cgttttgtaa catacctttt atatcagtaa catcttcctt aatttcctct
    19141 acatctgttt tcattattcc catttgaaca agtatatttt tgtttatttc ttgttgttgt
    19201 gtagataatt ctataaaatt ttctacagtt tttttataca tgtctctatc ttcttttttc
    19261 tcctgcatag tatttttaaa taatagagca catagtatac ctattgcccc cagactactc
    19321 aattcggtta ttaatttatc cattatagcc tcctattgtc taaatttttt atacttatag
    19381 ctttaatttt tgttatattc ttacatcatg caatattata ttttcaggat tatcaattta
    19441 atcttctgta ctttaaattg taggtttaat ttatagattg aataaataat aaatatatat
    19501 acaatttcta atataacaaa aaataagtac aaggcttact tattaaagtt aagaccttgt
    19561 actttacata aaaaaaataa ctaatacata gttattctaa atttactatt caactggtat
    19621 ttctaattct ttacatctaa ttctaacttg ctctctaatt actgctggta cttcttctat
    19681 tgtttttctg cctcttaaaa ttaaagctac atatacttct accattccac tctcacctcc
    19741 agattttctt acactaaaag tgcttatatt acttgcttca ttgacagaac tttgacttaa
    19801 caacatctca tatatttctg catttgctat aaaattattt gttatatcat catcttgctt
    19861 tgcttgacct atacttatgt ctgaaatgtc tttatactgc atttctactt ttctaccttg
    19921 tttgatttgt tctattttat ttttatcgaa tttaaacaat ttttacacct ccattttaag
    19981 cttgtggctc gttgttttca gcatcatatc taaaaatcat agatggacgt tttatagctg
    20041 tccatttatc tcctttttct actatgattt taggctgagc actttttatg ttggcttctt
    20101 ctaattcata gatttcttga taacttgagt ctgatttttt gatttcaact agtttcatgt
    20161 ctttgaataa gtcagattta tttattttta cttgaacttt agttttattt attaattgat
    20221 atatagggtc tccaagattt aaatcttctt caagtcctct atctagtgta attgtaatat
    20281 cttgttcatt agatgttgta ttaactacct tgtacattct attacctatc ataacataag
    20341 aatctttaat tatagaattt ccagtactct ctttaaaaat aaataaagat gcatataaat
    20401 catcaccttt acaataagct ctaaatagta tcttattctc tcctatttta attttatctg
    20461 gtggtacttc aaaggatatt ttttcagtag ttaaatcact tacagatttt acactttcac
    20521 catttataag catttctatt ctacttatat ctttattagg gtcttgtatt tttatcttaa
    20581 ttgatgaaat tgatttttca gtaatttcta tagcagcatt tgtcgttcct acttctgata
    20641 taatatataa tgtattgtct gttgcaagta catcctttac tgtatttaca tcttcagaaa
    20701 taggtactat agtaaattct tttaaaaatt ctactggttg ttcaatttta tatacatccc
    20761 tattttttcc agtaacccat actgaattat catttttaag tactaatata tggtcacttc
    20821 cataagattt tatttctctt atgtctgtta gtgcttttgt aaagaactta attatagtat
    20881 tttcactatc gcttcctaat cctaaagctc ccttatcatt atatccttgt acaaataatt
    20941 cattacctgt agttactact aatgtatagt ttttaccaca atgtacttct ttacagctag
    21001 atatagttgt aattctttgt aattcagtaa ctggattatt gtgacctata cctaattgat
    21061 attcggaatt tttaccaata gaccaaagac tatcatcaga ttttataaaa taagtaaagt
    21121 tatctccaca tgaaacatgc tttacatctg atacattaat ctgcacaaat tcatccactt
    21181 gatttataga caagtcttgc aataattctc catggtagtt tgtaccacat ccatacattg
    21241 ttccatcatt aagtaatata ataatatgag tcttagaaat agatacttct tttatatctt
    21301 catatggaag ctcagtataa aggtctcctt tgtataaatt tcctaatact aaaccataat
    21361 ctatgtcttt tgtggtaggt atcactatct tattgtttag aagtataaag ttatgtctgt
    21421 ttttaataga tgtcaaatca cccattacaa aattcatatg cttataatta aatattctat
    21481 tatcattatt tctactatcg tatctatttc caacacctaa ttgtccatag ttatttaatc
    21541 cacaaatata tatatcatta gtatctttta ttgctatatt tgcatattct aaaggaagta
    21601 ttttctttac tcttgtattg gtttttataa atgtatctct ttttgttaca tcaccaacac
    21661 ctaattgtcc attattatta aaacctgtac catataggtc tccattatca cttacataat
    21721 gtccacatct ataattcatt ccaatatcct ttgcctttga tgctattttt ttaatcttct
    21781 ctggagtctc acttcctgta cctgaaccat tactacattt gcctgcagta tatacatccc
    21841 cttcacttgt aagtaaaagt actgcattat ttctgtttgg agctactttt actacatttg
    21901 aaattggaat ttcagaaaat gaactttgat tgctattact atttagacct aagcaataat
    21961 cagtatttaa acctgtacta tatgcagtat tatagattgt tattatatag gtatttattt
    22021 catttggtat aacttctttt acattttcca tacactttat aaaactatac tggtcagtag
    22081 tatttcccat acctagttgt gaattattat tgtatccaca acaatatgca atgtttgtgt
    22141 cctttacaat aaatgttgtt gtatctgagc agtacacatc tcttacatta gttatattgt
    22201 ttacagtaaa tgtcaatacg tctggatggt tgctttcgct tcctaagccc agttgcccat
    22261 gagtgttttc tccacatgaa tataatgtgt tatcatcttt gattgcatgc gagtgagtag
    22321 tccctaaaac aacatctctt acattttgga tgtttacttt ggtaaatgta tttctattta
    22381 ctatatcacc taatcccagt tgtcctttgg tatttaatcc tgtggagtat agtgttccat
    22441 catttctaat tgcaaatgtt gtgttaccat ctatacttgt tgatattttc tttatattat
    22501 caaggtttat ctgagtgaac ttatttctat ttattgtgtc acctaatcct aattgtccag
    22561 aactattatt tcctgtggca taggctgttc catcattttt tactataaac attgtatttc
    22621 ttgatgttgt aatttctttt atatcatcca taaatataaa tgagtttgat tgttcagtta
    22681 tatttgtgaa tttttttact ggttcgttgt tatattcccc tatcccaagt ttgttattct
    22741 gattcattcc tgttacatat atattgttat ttttatctac tactactaca gtatttcctt
    22801 ttacaattat atcttttatg tcttttaatc ctgtatcata gttacttgtg ccatctatat
    22861 ttgttgaatt cccaaattgc ccactattag caatcccttt tccatataac ttggaattac
    22921 tatgatatat tataaaatta cttcctaaat tagaactctc agaattaata ctagtataac
    22981 ttctatgtcc agtaatggtt gagccaaatg tttttggata tccagtaata tatgaacttc
    23041 ctttcttaaa aaataatata ttatttgaca tccctattac tttttcaatt ccactaaaat
    23101 cagtctcttg tataaaataa gtattatgat ttgaatttgt agcctcaata aaagttccat
    23161 atcttgaata atcagatata cttggactgc tatttaatgt tcttaaatat ccatgatatc
    23221 ctgttaaata aacataacct ccttcgtcaa ttattgcaca accatcataa aaaggaaaaa
    23281 cattagttat tttaggtaac gttctaagtc catttgatgt agaagatgtt gaatttgttc
    23341 tacattgaga tactaatgct ttgctttggt tactattatt tcctttacct aattgataat
    23401 tataattgta tccagaaaca tatagtttcc cttcactgtt tatcatatat acagaataat
    23461 catatgctgc tatcttttca atattactta ttccctgctt atatggataa ttagaagttt
    23521 tttctatatt attataagga ttatttcccc atccatatac ttcttttgag tgatttaaag
    23581 ctatgacata attgcttcct acacaaaaat cctttacatt ctctatttct atttttgtaa
    23641 atatatttct attaacttca tctcttaaac ccaattgtcc attactattt aaaccacatg
    23701 aatataatgt tccattattc ttaagcacaa aagttgagtt tccgtttcct tttatatcca
    23761 aaacattatc tatatccacc ttagtcataa ctgacctgtt aacagtatct cccaatccta
    23821 actgtccata attatttaaa ccacaagcat acaatgtacc atcattcata acaataaaca
    23881 tattgctatc tgttaactct atcttcttat aatcttgaaa attatcactt aactttacat
    23941 ttaaaaattc actattgtcc tttgtaacat ataaataatc atcattaacc aataaacctg
    24001 aataattatc taaatttgaa gattgcacat ttgaaaactc atacagaaaa gttgtatgaa
    24061 aaaatgaacc aagttgacct gctaaattac agccagatac aaatatctct tttgaaccat
    24121 ttattaaaaa attaaattga gaaccacatt taatatcttt tatattttct acattaacct
    24181 tagcaaaagt atttcttgat gctacatctt tattggcatt ggctagttga ccataattgt
    24241 tttgtcctgt actaaacagt gtattatcgt attttaatat catagtatga ttatttccac
    24301 aagaagcata cttaacatta tttatactag aaagagtaaa tacaattgaa ttattattat
    24361 ttcctgtacc aagctgacca actccattat agcctgtagt atacatagtt ccatcattct
    24421 taataagaat tgtatgacta ctaccacacg ctatctgttt tacattatcc ataccttcta
    24481 ttttattaaa tacactttta tttaaagtac tattaattcc caactgccca tttgaattta
    24541 atccacatgc atgtgctgtc ccatccattt ttatgataaa tacagattga ttataagtca
    24601 ctacatcttt cacactatct atatttactt tagtaaaagt agctctattg ttagtatcac
    24661 ctagtccaag ttgaccactt gagtttaaac ctgctgaata taatgttcca tcatttttaa
    24721 gcacaaatgt aaagtcataa ccacatgcaa cagtttttac atcatctatt ggtagcttag
    24781 taaattcata atatactgta gactcaatta cacctaattg acctacatta cttgttcctg
    24841 ctccatatgc aaatccatct ttagttactg ctacactgtg ttttgaacca caagatacat
    24901 attttacatt atcaattttt actttactaa acatccttct ctctgacgaa tcttttccaa
    24961 gtcctagttg aaaacctgta ttatcgccac aagcatataa attaccatct gattttaaac
    25021 caaaggtact attacttata ccagtaaaaa attctacaaa atcataatca ttatatcttt
    25081 tatcaaaatc atcaatcaat atgttcttat cattaaaata agcaccacgc tgtaaaagtt
    25141 tattttgctt cattattagt actacctcct ttatttatct tatttcatat gaatatttac
    25201 ttagagttat atctttttgt tcttttaaat aagtgttact agattttgtc tcaacaaagt
    25261 tattatccat atcatgtata tatctaactc tatttgcact aaatggtaat actacatctc
    25321 taaaaatcac attaccaatt tcacctgtta tacattttct atttaaatct aacttaagcc
    25381 cttctatagc tactatgtta tttccatttg ctaatgtatc ataccaataa ccagcctcat
    25441 ctacagttac ttctgactct aattctaggt atattaatat atctagcact ttttcagata
    25501 atttgttata gctatttttt aatactgata tatcagtttg tatttgacca cttataacat
    25561 catcaaaaga tatattttct atttttttaa ctacctcatt tatagctcct gataaatctt
    25621 tagaatctgt agttaatata tctgtatctc caatttttac ttttatttct tttatatttt
    25681 tatcaaactt atcatctaaa tcttgaatat ccttttgagt tacaaaaacc aacgtcgggt
    25741 ctacttctaa tgtaacattt gaagtattgg acaattgtaa aatcattttt acaaccaaat
    25801 ctttaatact gccatcttca gcacgtggct tatacgtctc tggatactta cctatagcta
    25861 ttatattatt ctcattatcc agaacagcag cttctcttat cataaatcca ccaactgttc
    25921 ctggtaaaat agtctctata actatccaat taggattttt ttcatcaatt cttagagaat
    25981 ttatatttcc ttcccaaact acattcttta aagcagtttg ttcctctgtt ggctcataat
    26041 attctccatt actatctcca acttgaaact tggttaatcc aacaagctct cctagtgcag
    26101 ttgcatttgc tattttttct ctaccaattt tggttaatat tatataaaat ttttcttcca
    26161 attataccac ctccgattta ggataaacta ctacattttc tacgcctgta tcatttgcaa
    26221 tagctatatt aatcttacaa ttattttcaa tgcatttaat gcttaaagga taaaccttta
    26281 tttcttctct acttaacatt ccagctccac agtttacaac agcactacat tttataattg
    26341 gttcaaagta tggatgaact tttacctctt cactacatac catacctcca ccacaataga
    26401 ccatactttt atctagtatt attggttcta aatagtgtaa taagtgagca ggttttactc
    26461 tttcaatcat ctcgctacaa tctaaaagag ttttatagtc acagttattt gctataaaac
    26521 tcaatacgaa tgtaaattca tcactataaa cttttatatc tgtttctgat tttgtatatg
    26581 cctcacatat actttttata acttcaatag tactagtacc tctgcttctc attttagctt
    26641 ttatattgct acgtcttgtg tcaaaatcaa gttctttttt ttcaatgcag agtatgtctt
    26701 cccacatatc taatccccat gtcgctgtat caacaaataa ttggttaaag gtatcatcaa
    26761 tatcttcttt aagaatattt aattctgtat cgtatgcacc ttgtatctcc tctacaatgt
    26821 aatttctatc aaatgatggt agtttatcaa ttagcttcat tgattttcca cctcactaaa
    26881 attaacagtt gttacactag gtattttatc ttcattaata gttatattat ctgtacttcc
    26941 atttataagt agattactta aatcgtgtac accagtagta tttataagta ttcccatgac
    27001 ttttgtatag attatctctc ctctaatatc tctaaagtat gtatttatac tttctaggaa
    27061 agattctttt acattgtcta atgtatatcc atcttctagt ttcattactg cacttatact
    27121 tatttctatt ggtaatggtg tcacaactgt tatagttggt ccaataggct tctcttcatc
    27181 tatatgttgc tgacaccttt caatcgtttc tgtatcaaca gcttgattat tttccccaaa
    27241 tatcaagacc ttaactgttc ctggaccatc ccatcttgga taaaccttaa cattatagac
    27301 tccatctact tccaaagccc attcttcata gtgagcttta tttccacttg tagcttgatt
    27361 tctttggatt ttataaaatc tttcttttag ttcttcatct gtctctatat ctgtaccacc
    27421 ttcaaaactt cttgtgttag taatctttgt tactccagat atattatcaa ctagtttaaa
    27481 ttcacaattt gtaggtaaat tatatttctt accaacttcc agagcttgaa ctgggctatt
    27541 gtcaccttct tcactaccaa tagttacatc ttttattact acaaatagta aatctctata
    27601 tgatattatt gtgccattat ttattacagt tcctttctct ccaataaatt caacttctcc
    27661 atttgactct gtacctaact ttctatatac accaaattca ttgactcttt tatcaagaaa
    27721 ctggttatat gtgtcttgta taaaagccat tttatgtatc tttgaaagtt ctagatatat
    27781 cttcgaaagt tctagattat ttccagatac catgttgttt agaaaagaac cttctccttt
    27841 ataaatatca agattaatat tttcaagagt tctatttttt attacttcat atgtctggtc
    27901 actatacatt tatttccacc tccccataga tagtggatac ttttacattt gcactcaata
    27961 cgtctctgtt aaagttagca ctttttacgt ttacttctaa tatatatgga tttattagaa
    28021 gggcctcttt tatgaatcta ctagcttcac tttctgtaag accttttgta tatttttgtc
    28081 ctattagttc tgaaagctct gtcccatatt ctaaagagta tatctcatgt tcatatctat
    28141 ttgtctttat acacttgtat atccaaactt ttaaggcttc ttttttttca attattttaa
    28201 agtcaccttt ttctaaaata ggttcatctt tttcaaaatc ccatgccact tcacgaaaga
    28261 ttggcaattc ttctgtttta ggtaagatat aatcctctgg gacacctata aaaggaaata
    28321 ttgtactcat tataagctca ccaacttact tacaacagca aatttttcgc ctattctaaa
    28381 cattattacc atatccccag attcaaagtt atctataaaa ggatttttta cttcatgctg
    28441 gtgttcttga tttgtttctg tgtcaaatgt ttctagctgt ctatcaatca tccaactatc
    28501 tatcaaaata tcttcttttt ctaatatgat gttatttgtc tctattttta aatctggtaa
    28561 tttactttta atttttccaa taaaaaaaga aggttgatta tgatactttc cttcttctct
    28621 tattattcct ataaattcat ttattggatt agccattata tcaccatcct tttataatac
    28681 tctcctagct gtattaaaat ctcttctact acttaactta cttattttaa ctacatcacc
    28741 tttttgtgga gcatgtaaaa attctccatt acctatatat aatccaacat ggctgactgg
    28801 attatgaaaa aatactaaat ctcctgcttg aagatttttt tgttctactt tcttgccttt
    28861 tttagattgt tgatttgacg ttcttggcaa actaacatta acttttttaa aacagtagac
    28921 cattaaacca gaacagtcaa aactacttgg tccatttcca ccccatttat aaggtttacc
    28981 tagatgtttt tttgcctctg atattactat tttagcttta tcagatacat taccagaata
    29041 accaccaata ataatttttc cttttcttct tccaaattta ctagcttctt caacatttcc
    29101 aaataaaata tctatatggt atgttccatt tttttctata gttattgcag gtcctacgtc
    29161 atttacttta tagactccat cacgaccaga aactcctgta attacctgta tttcatctcc
    29221 atagttcaat aaaggatgtt tatttaaaaa ctcttttgta taataagttt gctcatattt
    29281 accaaccata ggagcagcgc aagttttttt agatgggtca agttttttct ttctacaatc
    29341 tgtatctcca ccttcttctt ttctaggaca gtaagctgta aattctgctg taaactcttt
    29401 tcctcctgca taatcttctc cccctaaatt actttcttcc ttaggttcat cctgtcctgc
    29461 tgacttttca tccataagat tttgaaaatt aagttcaagc tcaatttgat attctccatt
    29521 ttgccaagta tgtttgtctg tatctatata aaatagtcct acaagctttg tataagaatc
    29581 tttaactttt actcctctac cagttataca acttacatct ccataacctt taagagaaca
    29641 gcttttttct atcccattaa actcgctatc aatatctaca tcttgatttt cttgttgctg
    29701 aattactttt tgcattatta catttacttc cttaaaaatt tcattatcta ttttttcgct
    29761 aatcttgctt ccatactggt ctaccactat tactttattt tttacatttt ccatgctctc
    29821 cgaaaaggtg gtatttataa tattaaatcc ctcttcaaac ataacactta atgtaacagt
    29881 tcctttttca ataacattaa acttatctaa attagcctct atcatatact ttttctttgt
    29941 ctttttactt gcctctgtat atgcactcat tattgtgtca taaccattta ctcctataaa
    30001 catctttgta tacttgacat tggtctttgc tattgttcca actgaaagcc tattttcagc
    30061 aaatacttgc tttgctatgt cttcaactaa cttatcttta aaattgtatg acacttcact
    30121 ttgtgtaagt aaaaatccca tatctttaga tacaaaacta atttcattac tgcttgaatc
    30181 tttagaccta ttaattatca ttcctctaaa gagttctttc tcatctacat agaaacagac
    30241 tgtactagct attggtatat cgatttgttg gaaatttaca tcaaatgatg attgtattat
    30301 tgaaaactct agtgtccttg atggagattt ataatcacct gaccatgata ccttgtctac
    30361 tatgtcagtt atgtcatata tacttccgtt ttttatgtgt acccaaatct taataataaa
    30421 aaatcacctg ccttttcatt taattctatc agcagttact tacaacttat tatctataat
    30481 agttattgtt ttggagttac ttttggtatc tttattcttt tatactcttt taaatctaat
    30541 gtaaaatata catctcgagt cccatctctt tcttcataac taaacccttc aattatgact
    30601 tccatattta tatttgtttc cgtaattgta aatcttaata taaaaccttc cttcatccat
    30661 ttttctatct tatttacaca atcatatggt gatggaaaac ctgtatagtc acagaaagtg
    30721 tagtctttat ttggaaaaaa acttgatatt gaaatgcttt taagagctac accaccaaaa
    30781 gttgctactt cacctatttt gagtatacta gaagagttta cagcagcttt tccattaata
    30841 ctaaaggaag atggaaatac tggaaatcta aatctatctt ctgcttgtct aagccacatt
    30901 tccattataa gacaccccct aactgtgcca attggatact tgcaactaat tttgatgtta
    30961 tcttttctat atcagcttct tctctaatca ctattgtatc agctaactta gctatgttta
    31021 tatttccacc attttttctg cttctatatt gatttgcttc ttgtttagtt aaaaccattt
    31081 caccttcatg gagtctggtt tgatagtcat tataaggaac atagttcaat ccaaatgcat
    31141 tattaccttt cttacttgaa taagctttac cagaatcacc agcctttgtt ccagcatatg
    31201 gattatcttt gtaatttttt ttactctttt ccactagatt taaaactgtt cctgtgatgc
    31261 ttccattttt tatcttatta atcatagttt gccaccattt gcatatatct ttaactattt
    31321 tacatacttt atctaatatg ttaaaaaaag ctcccaatat tggctctata attttccatc
    31381 cagtttccaa cagaggtcct aaggtctccc atacagtttt ccaaataaca cccagtgtct
    31441 ctataaaatt gtttatttga ggtgcatatt cacctaaaaa agtaaaaatt cttgtgataa
    31501 taggactaac agcttcaact acaggtccga ttagttggaa tgctgtagtt actattgtac
    31561 caaatatact tattaatcct tgtgcaattg gtgatttatt gtttatacta tctagtaaat
    31621 tatttactaa gtttactact ggaagtagtg aatctattaa tgctgtaaaa tcaatatttt
    31681 gtaatagtgt acttcctgcg ttaacaattg cttttggtgc attccctatc attgttgctg
    31741 catgattttc aaaacgttct tgcttatttt caaccatcat tttacgcttt tcagcctcat
    31801 tagaaattcg atattgagta gaatcagaaa actcttttcc attttttaca cttctagatt
    31861 gcatctggtc atatttgttg ccaataatta tcttaccatt cattacattg cctattttac
    31921 cagccatttt ttcagataag ccagctaaat tccctaatcc actttctata aaagttttta
    31981 ttttctttag tccttgacct aaaatatcat caaaaggttt aacaatactc ttcaaaccat
    32041 tgttaatgct tgtttgagct cctgatatta tacctggtat tgtattactc atttctttag
    32101 ctaaccccat ctgctttaca cttatgcctt ccaatgcttc atcaaaagtt ttataatttt
    32161 ctcctaccag agtattaaga gattccatat ttccttttgc tgcacttaag aaagctgctg
    32221 atacatcttg ttcactactt gtattcatat ttaaagctct aacatctacc atagcttgag
    32281 ttatatcttt ttcttttttg ccaccagtaa tattactaat cattttagct ttagttccca
    32341 ttgcaacaac atcttcaggg tcaaaaggcg tatcatttgc catatttact aaactgtcat
    32401 aatacttatc aacatctttt tggctagttt ttccagtatt tcttttcatt acactttcta
    32461 gaacaacttt ctgattttgt tcctgaccaa gtaagtcaac accctttttc acagcgacac
    32521 ctatagtagc accatttgtc aaatcagata tcttcccttt tatcgaacca agtattccac
    32581 ttgccatatc ctttacagct attgcaccac tccatacctt acctgcaaac aatctcaatt
    32641 tgggaaatac tttacttata atgctacttg ccatatcttt tatagctatt acaccactcc
    32701 aaaaagtatt tttaaacaac attaacttag gcaaaattct agccatagca ctacttacca
    32761 tatctttaag attaatactt ccttgataag gacgtttctc tactcgtttt aattttccca
    32821 agatactact tatcactctc ttagtcatat cttttgcttt tattacgata ttccaaatct
    32881 tgccaccaat cttttttaaa tttccaagta atttattttt agttttttct acttcatcac
    32941 ttttagcttt aaatattaat ataatcataa tatttgaatt aaactcattt ttcttttgaa
    33001 tcaacttatt aaaataatca ataatcatag ctatagttat tgctagtctc ataatacttc
    33061 catttaaact tccaataact cctgaaacag catttatgct agaacttaat tttgccatag
    33121 ttgaacttac actactagca gtagtttgaa cttttcttaa cgaggaattt aaactgttta
    33181 ctctactact tgcacttcca atagaatttt ttatgctact agccattaca ttagtggaaa
    33241 gtgaaacagc cacagttgct ctcctaaaat tatcagttac tgatataatt tggttcattt
    33301 ttggtgtgta attatctgta agatacatat ttataccttc ttctctcaca tttcccatta
    33361 cataccacct cctgtcaaag gacacactcc atatccatgt ttcatttttt caacttcttc
    33421 ctcaatttct aaggcgaaaa aagcttcaat aagctttaat tcgcctttat ccattgcata
    33481 aaaaagggac ggtcttatac cttttttctt ccaataatag tacattattg tagtcttggt
    33541 atccgtccct attagttttt tacctcttct atcactgcat ttttaccata acccataaca
    33601 tcttgaagta ttctatatag gttggtaatt tcacctggta ataatagttt tcttgccaat
    33661 tcttttggtg ttggagcctt aaatttatcc attagttcct tatttttaaa taaaagcttt
    33721 ccatccaaat cacaaacacc ttctataatt gtaagcatct gcatctccgg taagtctata
    33781 tccgttttca tattttcatc aattttaaga caagtatttt gtatctcttc atctttactt
    33841 attgttaaag ctctacacat tactttaaat tcctgcccaa atatagttga taatctctta
    33901 agttcaacta tagtacttgg tctttctaag ttttctgtat ctgcatttaa aagtaaatct
    33961 actatgttta tattttttga taatccattt tcattcatta ttatttgctc ctttatcaat
    34021 caaattcaat caactaactt ttttacttat taactaccta aatttattaa gtatatatct
    34081 actaaatatc agtataaaac caaatataaa actaaattat atcaagaaaa tcatactcag
    34141 taaatgtgaa aggtgcttct atctctcctt ttactccaac ctcccaatca gctaaagtta
    34201 aatcatcaaa tgctatattt tttactgcta ttctttctgc tccataagaa tctgggtcat
    34261 ttaatttaga tatagcaaca aatctaggtt cagaacctct ctttatcttt tctccaatta
    34321 acttgtgcat tcttgaacta acatggtata gagttattga accttttcct ttatatccca
    34381 tatactttgt atcagtaccc atttgacctg ctattataat atcctctttt gtaaattcca
    34441 tctttgcttg aaacttcttt acttctgcta ctttgtttcc atcaagccaa agttctcccc
    34501 aagtaccact cattacattt ctagcttcca tatttgccat attaataatc ctcctatatt
    34561 tctattgata aatctatatc ttccatagca tcaagtactt ttatttttgc ttttaaaaat
    34621 actttagaac ctgtgttagc ttcttttatt tcttgtaatg tcatataaga taaatctact
    34681 ccttttgatt ttaaatacga tttttgtgct tcaaaatcta tttcaacagt agaatcagat
    34741 tctataagtg ctgacttttc taattcttct aaataacttt ttatagctac tatcaataaa
    34801 catttgttgt cataactgtt agtaaccttt cctatatagt catctattat cacctttctt
    34861 atgtcactat gtataatatc taaagtgtca actattttta ttttctggaa catttctcct
    34921 ttttcttctg ttaactcagt taaagaattt actcctcttg caattcttat agcccctgct
    34981 tccttaataa gtataagctc tcctttatta acccttgatt ctgcatcaac tttcgtcatc
    35041 ttaggtatat caactacatc actaagctta gtataagtta ctgattgact taaaggtgtt
    35101 cctgctataa gtccagccac cctacttgta aactcatcaa cactgtattt cttttctcca
    35161 actaacacat cttctgtagt aaaattaatt atcccttcat gatttcctac aacttttcct
    35221 aatacagctt taaccttaac cttatctata tctctaagtt taattatcca attttttata
    35281 gcagtcttat cagcttctac tgcttttggc atacatagat aattaaattc cttagtctct
    35341 aaaaaatcta atgcagtttg aatatctgct tctccttcta ttacataaac taataattta
    35401 tttggagtgt taacatttcc catcaaagct aaatttatat actctttatt ttcagcagat
    35461 aaatcaactg gtatatcctc tttttcatgt atttcattaa gacctagtgc cttagcatct
    35521 ttaagcacca ttgcaattat tcctctagct gaacgttctt taacagttgt agctagctcc
    35581 ttaaatgata tgttgatact tggtaatcct atagccatac tatcactctc ctaaatttaa
    35641 attgatttct tccatatttt catatactac atcttcttca tatacactat ccagataatt
    35701 tagtgtaatt gtaaagttca atacataaat tgactcttct tttttaatac tttgttctag
    35761 ctttgttata tttaattttc tgtctgttac ctttatattt ctgttgaata acttatttaa
    35821 ttcatctgaa atttcataca ttctaatact ctttgactgt ggttttggta agtattttat
    35881 agagataaca atatctttat tattcgtatt taacattata ggtgtacaaa taactgatag
    35941 tatacttaca aaaaaacaag acccttcaga gccttgcaca ctttcatcat caataaaaat
    36001 actttcagta aagttttttt tgagaatctc aataattgtt tctaatattt ccttgtattt
    36061 aagcaaataa tcaccacact atcactaaat attcttgctt aatctgataa tcttactata
    36121 aatgatataa gtcattttta aatatacatc tcatttattc ctgtcaaata tcttctatat
    36181 ttttaggtaa tattattctt ttcaatttat cacctccttc aatatggatt tctttcacaa
    36241 taacattatc tcacatattt tattgcctag tgttgcaata gtgtatataa agtgttgtaa
    36301 agttgtcata ttttttataa tatctcactc aatttaaata tcattttttt ctttaaattg
    36361 tagcaagatg ttctatctaa gtgtagtttc atagaaatat atgtcatatt gttttttgtc
    36421 ttactattat aaaaaagatt aaaaaattcc atttctatat catttagaca tgttagagca
    36481 ttttctatct tctctttttc tatttctata tcttcttttt ccatttttaa ttttcttaat
    36541 ctttcctctc tttttaacac ctcattttcc acagaagaac ttatgttata tgtgttacta
    36601 gtcttttctg tatataccat tgctccacat ccagagtatt cattctcaca tctttttatg
    36661 tccaaattaa tattctttat ctttatatcc aaatacttat aattatgtaa tctttcatct
    36721 gtttctttaa ataatatatc ttttttgttt tccatagtac ttctcctttt ttatatactt
    36781 attattagct tcaaatttac aataatctct ttagtgcaca gttttttact aatctcacaa
    36841 ctttcaagaa catattgttc tataactgta taaaaaaaac ttcttctata ttttgttcta
    36901 aaatactaga aatcttctta gccataagaa gaccaggatt ttttatacct ctttctattt
    36961 gagatatata gtcatttgta attccagcct ttctggcaag ttgaatttgt gtcatacctt
    37021 tgcattttct ataatatttc aagttatttt taaacattgt tttatacctc cattaccatt
    37081 aagaatattt tgttcttcca cacttagatt atatagaatc atttgttctt tatcaataga
    37141 ttttagaaaa aaatattctt ttatatttta ttagttttat tttttagaac aatttgttat
    37201 aatctataca taaggtggtg ttataatgtt tgccaaaaga ttaagagaac ttagaaagga
    37261 atttggattg actcaaagag aacttggaga aaaagtaggc gtttcccaaa gagtcttagg
    37321 gtactatgaa acagaaaaca gatttcctga tgaacacatt ttaaacaaat tggctgatgt
    37381 atttaatgta tcagttgatt accttcttgg aagaacctta gttaaggaaa atattgatac
    37441 agtagctgca catagaaaaa atccacatga agagttacct gaagaagcac aagaacaact
    37501 taatgattat atagaatttt tactaaataa atataaaaaa aaataaacca tatgatgagc
    37561 agtctatttt tctgctcttt taatataatt taaaggcaaa catacattct attttagggg
    37621 gatttttatg aataatttgg ataagctttt tgaattagct tctcaagaag agataataat
    37681 tcattatacc acttatattg caggtgattt agaagggcta tatataaaca aacatggtat
    37741 taaaattata tcattactca gtaatttaaa acaaaactca aaaaaattga catccatctt
    37801 agctgaagaa cttggacatc atttcactag ccttggatac tatgtatcct cttataacga
    37861 ttattataca aaaattatta tagataagtg cgaaaataaa gccttaaaat gggcttgtga
    37921 gttcttaatt actgaagaag atataataaa cataattaat tctggcatca cttgcgttta
    37981 tgaaatggca gacatactta atgtggatat tactttcttt caaaaaagat tagaattttt
    38041 atcattaaaa aaacagtctt tacaacttgg aaataataaa tatttaatat taactaattt
    38101 gccgtatttc tacatatttg atccaatttc ataataaaaa tagtagtaat tttaactggc
    38161 ttaacagtaa aatctatata tttattttaa caaattttgg tttctataaa ttcaatatta
    38221 atatataata atgatatcat attatttaaa attctaaaaa caaatatatg cttttgttaa
    38281 gaaaggttgt ttgatgaatg tataaagaaa agttgtttga taattatttt aagttcttag
    38341 cactattatt ttggccaatt atgtggtata agtggatagt aatttcaaat ggtactcttg
    38401 aaaatatgtt atttaccata tatgcaatcg tcgcaattat tttcatcatt ttatattcgg
    38461 tgtttatgat aaaatataaa gacattacac aaatagattt cttttacagg ataagtactc
    38521 tacttgcttt tatatttaca ctttttagct ttttaatata cccaaagagt ttatttttct
    38581 tgtatttaaa gattattttt actggaatat acctttatta ttcaatagta aaaactctta
    38641 aatttaaaga tgatgaaggt gtagtgggta ttatgagctc acttttatta attgtaataa
    38701 ctttgttcta ctaaatttaa ttctatttga cttaatatgg ctttaaatat tagacatcta
    38761 cattattttc tgatattatt taagatggta gtcttatatt aataatgaaa tacactatga
    38821 aggagttaac tattatggaa aaaaaagttt tagcaacagt tggagaaaaa gagataacta
    38881 atattgatat tgaaaatgca ttaaaatcat tagaccctta tcaagctatg caatttaaaa
    38941 ctgaagaagg aaaaaaacac ttattaaatg atttagtgaa tcaagaatta ttcttcttag
    39001 atgctaaaga agaaaaatta gatgaagaag aaatatttaa attagaaatg aaaaagatag
    39061 aagaaaatgt attaaagcaa tttgctataa ataaagtttt atctagtgtt aatgtaacag
    39121 aagatgaaaa agtaaaattc tttgaagcta ataagagctc tttctctaaa ccagaaagtg
    39181 caactgctaa acatatatta gtagatagtg atgaaaaagc taaagaaata cttgctcaaa
    39241 taaaatcaga agaaatatct tttgaagatg cagctcttaa acattcttct tgcccatcta
    39301 aagatatggg tggtgattta ggaacattcg gtagaggaca aatggttcct gaatttgaag
    39361 aagctgtgtt ctctatggct aaaggtgaag taagtgaacc agttaaaact caatttggat
    39421 accatataat aaaattagaa gaccttcaag aaagtacaga gtctacattt gatgaagtta
    39481 aggctgaagt tgaaaaaagt ttattatatc aaaaacaaaa tgaagtttat ggaaataaga
    39541 taaatgctct taatgctaag tacggaaacc ttgtaaaata caacgattaa tcataaggtc
    39601 atatataaaa aagctgtctt ttcacaatat ttattagaaa agacagcttt ttatattaaa
    39661 gtttaaatat tcagtttcat attatcattc ttttattgta aagaactcag cttaaaagtt
    39721 taaataagat ttttaattat cattagctaa atttttatat ccacgtatta tctcataaca
    39781 gtaacctatt acatctcttc tttttattat cccaataaat gtgtcttggt catctataac
    39841 aggaatgaaa ttttgattta aagattttat aactaaatct tcaatatctg cgttgatgga
    39901 aacaggagaa ttatccattt ttctatttat atctgtcact ggaacatctt ccaatccctt
    39961 taagtccaga tttaaatcgt tttttaatgt ccataaaaaa tcaccttctg ttatagttcc
    40021 aacatattta ccatccttac ttattattgg aattgcagag tatttgtgat attccatttt
    40081 ttctagtgct tgccttatag tgtagtcttc atatatatat gctacttcac tttttggtgt
    40141 tagaaagaat aatatgttca ttacactacc caccgttact gaaaacttat aaatattact
    40201 caatatttat aatgttactt ttttgcagta actttctcct ttcttatttt ctaagtattc
    40261 ttaatactat acgctgtaac aagcgttttt cctttgctca ttttaatctt attatgcttt
    40321 attaatattt ttatatggtc tatcagtatc acttattctc tttttagaaa atttactaaa
    40381 aattaattga cttaaactta gccataataa ttttactcta cactattaat tttaacatat
    40441 ttatctcatt attaatgatt ttattttaat aattttaatt tattttgcta ttaattttat
    40501 ttacaaaaac tgaaaaaacc gctaaatgat tagcggctta tctctcatat tactagaaca
    40561 ctaatatata tgaattttta attataatct aactacgtta gcagcttgag gacctttagc
    40621 tccatctact acttcgaact caacgctttg tccttcttct aatgttttgt atccatctcc
    40681 agttatagct gagaaatgta cgaaaacatc tccttcacct tctacagata tgaatccaaa
    40741 tcctttttcg ttgttaaacc atttaactac accagttttc attaataaat cctcctaaaa
    40801 aaacacaaat atttagctac tcttttctgt aaccttatta ctactctatc atatatagct
    40861 atgtttgtca attattatta tttttataca ttaataatca atttttttac tttataattt
    40921 taaatgatta ttatctttta cactttattt ttctttataa ttttttaata atttattttt
    40981 attatatgga atcttatgga cttatcactc cagcctaaat cccatggcac caacattcta
    41041 tcagtattat ggcaagttac caaaggatat cctcttgagt ctaatcctgt cactgtcgaa
    41101 acatgtgtta ttctgccttt cttctcataa ccaacaaaat cccccggacg taaattataa
    41161 gcttctttgt atacttcttc ataggaacct ttagcaatta atgaacctct tccactatac
    41221 agtgcataat ttttaaaagc ttgtgcattt acccatgctt ttgtacctgc tctctcgcta
    41281 taattccaaa ttgagttctt tttgaacctt ccactttcaa acattatctg tgatgcaaag
    41341 tttgcacaat ctccaccttc tggattataa tccctatagt ttggattaaa tttcatacca
    41401 tgttcttcat cagctgcggc tccacagtat ttatgtgcat aatctatagc ctttttttgt
    41461 tcatctgtaa gctgtaactc tacaccatct tgttgcccaa tatagtttct tatatcctca
    41521 gattttatat tttctaaatt taaagagtct gcaaaagggt ctgtgtacca ctctttagtt
    41581 atgacatatt gattatctat aatttttaca tttagataat gatatgtacc tattctaaag
    41641 gcattttctt tgtccttttg attttcatat gaatacttat attcagtcga tactgaacag
    41701 attataccat agaggtcttt ttctttttct tttatttttt taatcttaac ccttgtcttt
    41761 atgtctttaa attttacacc ttgcttacta gaccagtttt ctaaatactt catctttttt
    41821 acttcatttt cataagccca cagaccaaat tttttatccg tctcataaag accttttaaa
    41881 atgttttcat ttttctctaa tattgcctta tttctgtagt caaataagtt ttcaagcaat
    41941 agtttatatt ggtcttttac atcatcacct tcaacatttg cagattccat gactttttct
    42001 tccatatttt tcatacttaa atcattgatt aaaaatacac ctgctgtagt agctaaagac
    42061 aaaaatacaa atgccattat acctttgatg tacttattct tatttttcag tattttcaaa
    42121 gctacacctc ccaaatagta caccttataa atgaaattac aaagaagatt ctgtcatata
    42181 caataatttt catatttaat aattctctat tttattatgt ccaatattaa aaattaattg
    42241 tatcaataca ctgttttttt tacaattttt tattttataa tctacttttt tctttttttt
    42301 atagtaatat atatgtatat aaatattttg gtatcattat aattaataca tactaatgga
    42361 gggtttttta tgcaaaaaaa agtcgcagca attaatgact tatctggaat aggaaaatgc
    42421 tcattatcgg ttgctatacc tatactttca gcattaaagg ttcaatgttg tccatttcca
    42481 acggccatac tttcaagtca aactggttat cctgaattta ctttcttaga ctttactgat
    42541 gaaatggtaa aatattcaaa tgtttggaaa aatttaaaag tcaattttga tagtatatat
    42601 agtggttttt tgggttcaaa gcatcaaatt gagatagtgg ctaattttat aaatgattat
    42661 cccaatgctt ttatcgtagt tgaccctgtg atgggtgata atggagttat gtatccaata
    42721 ttcacagaag aaatgagaca ggaaattaaa gaattagtta aacattcaga tttaactact
    42781 cctaatttaa cagaagcttg tttcttaact ggaaatgatt atactaaaag cgattataat
    42841 agagatgagc ttatatatat tgcaaaatct gtatctgatt tgggacctag caaagtcgtt
    42901 attactggta tattagaaga tgataatata ttaaatttgg cttatgatag agataatgac
    42961 catgtattct ttacatcagt caaatacaat aattgttctt acagtggaac tggagatata
    43021 ttcacatcta tactttgtgg tatgttagta aataaacatg atttgggagt agcggttaat
    43081 actgcaacag attttatata taaaactata aattacacat ctcaatttga tactgataga
    43141 aatgatggag ttatgtttga aaacttttta tcagatttaa ctaatatata aaatcaaaaa
    43201 aactatccat tttataaata cctataaatc ataaaattta ggtatttaca aaatggatat
    43261 tatttactaa actattggta tttcaattgt taccatagca ccaccagttt tcacagaatt
    43321 ttcaatatat aaaattccat tatgtttttg tacaatatta tttacaatat aaagtcccat
    43381 tccgtaatga gatttagaat ttctactcaa atctcctgta taaaactgtt ctgtagcttt
    43441 tgacaaatct gctttagaaa aaccacttcc acaatctgta actacaaatt ttaagtattt
    43501 attacttact gatacactta tgtatagttt actctggctt ggtgaataat ctatagcatt
    43561 tgaaattata ttcataatag ctctgaataa cagttctcta tctatagtta tatttttagg
    43621 caaattatct tgtttataaa actccacatc taagttttta gtactagcta atgcttctat
    43681 ttgcagtaag acatctttta taaactcact catattaatt gcttctttat ttaatatata
    43741 gccattctct gtttttgata tatctattaa agtattaata tatttttcta tttgagtgac
    43801 accctttgag atatattcca tgtattctaa taactcagga ttttcattta tttcaattaa
    43861 taagtcagta tttccatgta taattgttaa tggtgttttt atatcatgtg ccagtgcaga
    43921 tatctgttcc tttctatttt cttctagcat ccattgtttt tctaaagaat tctttaacgc
    43981 caacttcatt ttatccatag aaaaaaggat attgttaatt tcataaattt tactagattc
    44041 tacaacaaaa tctaaatcct gttgttctat tttttctgta gtatttttta aaagctccat
    44101 ttcaatatta aatttcttgc caaatacttt tgataatata acaatttcaa taaaaaatat
    44161 tatactaaaa ataatcatac ctaacatctc tggttttggt aaatatgctc ttaaaactgg
    44221 agaactatac tctgatacta gtttgtattt tattataaaa acttcatctt tcttaaaaaa
    44281 ctttatataa ctttctgaat atgcatgcct ttcttcaata tctctcatta aattccatac
    44341 ttgttttgat tcttttttat taaaagtgcc tgagatcaaa ttcccatcta aagtataaac
    44401 accatactcg tataaatttg gaattatatc ttcaattgct ttttcacttg aaataatctt
    44461 ttctttatat ttatcaaatt gtttttctga ataattagct ggtaatatta cacctgatga
    44521 taataataca gaaaatgata acattaaaag aagtgcaaat gaaattgtca taacaaagaa
    44581 taaagataaa tattttataa aaatagttct taacttttca acttttttgt tgttagattt
    44641 tttacttcta agcatttgtg ccatatcctc caaatatttt aattaattca taattaatac
    44701 ctaaccagtt tttatttgat tattttatat ttttcattgc taagttatat tttaacataa
    44761 taatataaat ataatgtaaa taaacagtca atttttattt attcttctga ctttttacct
    44821 tcccatttag aaaaccaaat acataaaatt acaaatgcta aaattgttac aaaaccacac
    44881 attaaacctg ttgattgata tgcttttatt gattcaacct ttatatattc aaccgtttta
    44941 gaacttgaaa aagacgacca aatagttata aatctaacac cccatgcaca aggaaaatac
    45001 tgccaaatgc cagaacccaa tccagttaat aataatgctg aaagtaacat ttcaactata
    45061 cctactccaa ttgatgttcc ttttccgaac cttaaactta agaataaatg taatatgtat
    45121 tcaaataaat tacacccaat taaaattaga attgaaatca tataaaagct tgatgtaaag
    45181 taagccttag atataccaaa tttaaaacct aatacagaca ctaatgttgc tacaaaacca
    45241 agacatacta agattatata tttacttata agagtaagat attttggatt agatgttgtt
    45301 aacatatgtt tataattccc tgcataatat tcttgttcaa caaacattga acacacaaca
    45361 cctgacaata aaggaaaagc tattgctata acttgtaaat atgctactat ctttaatata
    45421 ttatcagctc ctgaaacctt ataataccat aaaaacaatc ccatccccat taaagcaatg
    45481 caaatgtgca ttagtattat aaaatttctc tttaatttta ttaaatcaga acaaaatatt
    45541 cttattagtt gtctcatatt acttcacctc tctattattg aaccaagctc ttgtaactaa
    45601 agcaaataat acaaataaaa taacagatat taatactcct ggtaaaataa cagcattatt
    45661 taaaagttca ctcccctctg gtacaggaag cccatttggt agaatatgca atacaacaac
    45721 cattaatctt gaaggaatcg aatatggaaa tacataccac atttctgtag ttgagaaaac
    45781 agcaactcca acaatagtaa agaacatatt tgttagaact gtaacaaata taccaaattt
    45841 tgaagctaaa aacatacaaa gaggaatctg ccacataaat agtaaaataa ttaatatagt
    45901 tgcaatgata ttttgaccta ttgaaatagt ttctttatag attatcccaa caaaaactac
    45961 acctattgca gaaataatcg atgctataga acaacaaata atacagtaaa tcatttttcc
    46021 agcccaaacg tctttcattt caattggcaa tggtaaaata ccacgatatt tacttttttc
    46081 atcttttaat actattaaag aagatattaa tgttaatgct cctggaagaa atgtcgtata
    46141 ccaccagttg aaagcagcat tttgccctcc acctagtcca cacaaaagta tacaaaacac
    46201 tggaactatc catatcaact tcattccaaa agttcctttc atcttttgaa attccactct
    46261 aataaatctt tccatattac tcccctctct ttctattttc agctacaact ttcataaaaa
    46321 gtttttctaa gttttgttct tttgatactt ctccttgata accaattact ccattagaaa
    46381 ttattccgat ttcatctacg acttgttcaa cttcagacaa gatatggctt gataaaataa
    46441 ctgtaattcc ttgttttgga aaagaacgaa tcaattttct aagttcttca ataccaatag
    46501 ggtcaagacc atttgtaggc tcgtctaaga ttaaaagttt tgggtgattt aataatgcaa
    46561 tagcaatacc aagacgttgc ttcataccta gagagaattg acctgaacgc tttttaaaag
    46621 tatctcttaa gtcgacagtc tctaaaactt cttcaattcg agagtcagga agaccaagta
    46681 aagtagtatg gacttttaaa ttttctcgtg ctgttaaatt ctcatatata gcaggagact
    46741 caataagaga accaatattt gataaatcct ttctagtcca tctatgtccc tcaaacatta
    46801 tttttcctga agttggattt aaaatcccag ttatcatttt taataaagta gatttcccag
    46861 ctccatttgg tcctaataat ccatatatag aattagattt aattgctagt gaaatattat
    46921 caactgccat ctgctcctta aattttttag aaactccttt tacctgcaaa atataattat
    46981 tcataatttt catcctttct tttgtcaaac ttatttacaa gaatcattct aaatcataaa
    47041 tataaggatt ttataagaat taaaaaacaa aaaaaagatg tgttaaaaac acatcttttt
    47101 ttatcttaat tctattaatt ttccattgta gtatatctct acttcttcaa tccaaatgct
    47161 attatcttct tcttggatga catttttaat aatattattt atagtatata ttatattttg
    47221 ttcattcaaa taatcatctt tccaagaaac tctacttttt ttatctggtt ctatcaagtt
    47281 tattttaaca agattatctt tttccttaac ttctacttcc atgtctaaac cattaaaata
    47341 ctcatttgat aatgtatcta agattaatcg cagtttatcc ttaagtgaac tttcttcatc
    47401 aatctgtaag tactttacta ttttctcatc ctttgaaatt atctctatag gtattttagt
    47461 agttttttta gaattaatca ttttactagt tgtttcttct tttgcatctt catccttctt
    47521 tacaactgct gattctttag aatcaactag ctcaactgca ctgatgctat aatccataca
    47581 tgctgtactc aataaagtag tagcaattat taaaaaactt actgctattt tattcataag
    47641 tatccctctc ctaattctct ttcgatactt attataccat agtatagatt atatttttat
    47701 acttttaaat caatttataa attattatag taaattattt acaattctaa gctatttgaa
    47761 tttattttta tagtatattc tttctctaaa ttcgacagat ttttattcaa aagccctttt
    47821 atttccctcg tatttctata cttgttgcta tgttcttcac tatgttcata atcatatgaa
    47881 tcattgtcat attcttcatc attattaaat tcttcaattg cttcttttga ctttatatca
    47941 caattaaatt tatacttatt tactggtata tcaagtctta ccttagaatt tggaacttct
    48001 atgtccagga acttagcaat tggcatatta gagtacaagt aaaattcact ttcataattt
    48061 gaatttctac ctattttctc ttttatattt acattttcag gtatatactc ttctatatta
    48121 ttgataaata catcttcatt ctctgaagat atatccaatg actctgattc tatgtttaca
    48181 tttttaacgc ctaaaattga ttttgttgac aagtgaagat tgctattaga tattaagttt
    48241 aggttttcta atctatttac tttgttctct gttatagctc tactaaaacc tccataagaa
    48301 gttttatatg ttatagtatt tgaagctaca ttatcatata caaataagta tgaacttgta
    48361 cttgatgcat ttatgtctac attatttggt acatatatta taatttctct ataatcatgt
    48421 gaaaacatac tatttataga tgtatttaat aattggtcga aatttttaat ctttttaatt
    48481 ttattttcat attttctttc accttttaca actaaagtct tatcttttaa agttacattg
    48541 tatttgtaaa actcattatt tcctcttgtt gttacacgca catcttcact tgaacttttc
    48601 tttattgtaa cgtttatatt gtcaacagat atatctaact tgtcaatatt tactttttct
    48661 tgataaagtt tattttcttt tttaaattca gcttcctttt ctaaaccaaa gtttattagg
    48721 cttggcataa ctaaaatccc tgaccatgtt gtccctatta tacctattac caataaaact
    48781 gcagcaaata tagcaagttt tttattcatg tttatcttct cctttcttat tttctatatc
    48841 ttcaaggtcc ttatatatcg cctcaaaatt tatactatca tcattatatt catcagtttc
    48901 ttttatgctt tcttcttctc tattgtagta atcattatta tatgaatctt cattaatgtc
    48961 tttattcaaa tcttcatcat ttaaagtagc tttttttctt ttttccatct tttcatttgc
    49021 ctttatataa atattttttc tctttatcca atgtatataa ttatttagta attgtttacc
    49081 tagttttata gcaaataata aaatttgcca tgcaagtatc tcaagcccta caaatgctat
    49141 ggttgcgaaa atacaaaaca tcataacatc tggaaccatt gctataaatt taatcacaaa
    49201 tggaattaat ataacaaaag caattaatga acatactaat gcaatagtaa cagatacaat
    49261 agcacataca aacgcaaatg ctggaacaat tagaaataaa gataacacta ctaataatcc
    49321 ctttataact tgtctagata atccccctac accttcttct atacttggtg taagtttatc
    49381 atttatattt tcttttgatt tattgtactt ttccttagct tcatctttca agatagagta
    49441 atcctttttt atatttgatt taaacctact aaatttacca tttaatatat ctgtattcat
    49501 tatttttcca tctatatttt cttttgattt actatacttt tcttttgctt catcttttaa
    49561 gatagagtaa ccttttttca tatctgattt aaatttacta aacttatcat tcaaaacatc
    49621 tgtatttatt attttttcct cttcaatatt tttttcttta gtctgcaaga taagttcttt
    49681 ggctatagat tttggtgaac caagtgatgc tattatctcc atatcactct ttccctctat
    49741 aagaccatct acgaaatact cttcataatc tctcaatata tcattaactt cgctctcaga
    49801 aaaatctttt tttagataat cctttaaaat ttcaagaaac tcagttttat tcaagttcat
    49861 tacctccctc atcttcactt attaaaatct caacagcctt tacaaattct ctccactctt
    49921 ccatcagatt ggataaattc tcttttccta gtgaagttat tctatagtat tttctagcag
    49981 gaccttcatt agattctagt atatatgttt cgaaatacaa atcttttgta agtcttctta
    50041 gaataggata tattgttcct tcatttacat ctattacttt agagatgtta tgtactatct
    50101 catatccata catatctttc ttagatatga gagcaagtac acaaatttct aaaacaccct
    50161 ttctaaattg tgtgttcata tactccatcc tttctttaaa tacacagtat tgtgttttac
    50221 aaggtactat gttaaaactt cttatatcct cataataaca cagtactatg ttctgcacaa
    50281 tagttatttt taaatattct tgttgattaa atccttctat aaatgtataa tactctaatc
    50341 agatatattt tatgaaagtg gtgataaatt ggctaaaatg aaagatgata aaacaatatt
    50401 aatcttaact gctcaatttg gtgctggaca tataagtgct gcaaaagcag tcaaagaatg
    50461 tattattgaa aaatatagta actataatgt tgttatacaa aactttataa atgcaagtat
    50521 tcccatgatg aataaaccta tggtaaaact ttatgaaaac aatacaaaat atactcctgg
    50581 attatataat tactattatt actttaagaa atcgtttgat tcaagacatg atttatctca
    50641 taaattatat acacctaaac tttctgagta tattgctgat ataaatccag atttgattat
    50701 ctctacattt ccactagcgg ctgcttgtgt aaataacttt aagataaaaa atcctgatat
    50761 aaatatacct acacttacag ttataacaga tgttgtagat agtatggaat gggtttttga
    50821 aaatacagat ttgtattttg ttccttctcc tgaaataaaa aatagatttt ttcagaaagg
    50881 aataaatcca gactccataa aggttactgg agttcctgtt gataagagat ttcaaattga
    50941 aagtaaagaa ctatgttgtg ataaatatag actattactt ctaggtggag gaagaggcct
    51001 atttgatata gatgaggatt ttatgcattg gatagatgaa tttattgaag aacatagtaa
    51061 ttctatagaa attacaatag ttactggtaa aaacaaaaaa ttatatgaca atctaactca
    51121 taaaaaacct ctaaaaaata ttaaagtact tggatttgta aacgacatgt ataatctaat
    51181 aagagaatgt gacctaatgc taactaagcc tggaggagca actatatttg aagctattca
    51241 atcacaaact ccagtactcg tgaaaatgcc aaaagttgga caagaaattg aaaacgctaa
    51301 atttataata gataagggtc ttggcatgat ttatagtgat gacctagacc ttaaaaacat
    51361 attttataaa ttagtatcaa atgaatttga ttctataata aactttatga aaaaaaattt
    51421 agaagaattt aaaacagtta ttcatccaga gaaaattgct gattatatat cagaattaat
    51481 agataatcat tacagttaaa ttgtactatt aaaaaatttc aaacataaaa ttaaaggcaa
    51541 tcaagtatgc ttttacactt gagaatttac tcatagtgtt taataatact tgattgcctt
    51601 tatcatatca aaatcaaatt gttatattag tatatatttt tcttgtactg catatacagt
    51661 tgttgtattt cttccatact tctctttaat tctatttgta aatctgaagc agtctggtaa
    51721 tccttatttt ctatagcttc tctcactcta gtgaatagtg attctctagt taaagtatcc
    51781 ttcataatat tgaactttaa atccgatatt gagttccaaa ctacctcatc aagcgcatcc
    51841 atattttctt ttgtgtgtat cttgacaata cttcttattt tttgaatccc agcctctatt
    51901 attctagttt ttaatttttt ttgccactta tctatagctc caatcttaaa tgattctatt
    51961 atactatcag taaatacatc accttgtttt aaagatttta attttgaagc atatatttct
    52021 aagtttttca tattttcata aactgtagcc ggtggtattc caaatcttgc atttctttct
    52081 tccaaactat aatgttcaaa tacatcattt tcatctctat atgctctatc tttttctaaa
    52141 tagaaacttt cttcacctac atttttagat aactcttttt caagttcttt tgtactaaga
    52201 ccactcttag ctgctgcttt tataccatcc aacattgttt gataacatcc tgctattact
    52261 aaatacgtgt tagatagagg gcttggtgac cttaactcaa atcttacagt ctttggattt
    52321 ttcatatctc ttattaatcc aacaagcact gacctatttc ttgatggaat ctcataacta
    52381 tgccctaaag atgtaactat gcatacagga gcttcaaatc caggaactaa tctattaaat
    52441 ccatcattag aagctgttac aattgggttt aatacttcat aattgtaaag aagtcccata
    52501 agagccccat atcctagttc acttagataa tcttctttta aatcttttgg agcaaataga
    52561 ttttttatac ttccatcctt taacttcgca cttactccta catgtgtatg tccaccactt
    52621 cctgctactc catgaattgg ctttgcttta aatgtaactt ctagtccatg tgatgtaaat
    52681 acatcctcta taacatctct tactaataat tcattgtctg ctgcttgtaa tggtgtagaa
    52741 aacttccaag aaacctctaa ttgctccata gcatggtttg ttcttccatc tatactaata
    52801 gaactttgta ttcctccgac ctctttgtga gccatttcag ggtttacacc tagcttttga
    52861 agtataatta aacttttctc taaacaagtt cttataatac catgagttct tttccagtat
    52921 tgctctttta ggctttgtga tacatataat ttctctaagt cagctttatc ctcaggagta
    52981 ttaacccaga actcaagttc tgtagctgct gttaacatta tttcctctat atcatctact
    53041 gaatctattc ctatgttatt tattacatgt ggatattctc taaatatttc atacattgac
    53101 tttttaaagt acttatctgc tttttgaagt actcctctag aacatacttt tttattatca
    53161 tgtattaaaa atgcaggtat ctttaatgtt ccaacaggta gacctacttc ttcgtctata
    53221 tattccatat tgtaatctac ataccaatga caacttttat ctggcattaa atctactttc
    53281 gcattattta atgtagctat attataaagc tcaacacttg aaccatcagt ctgtatagct
    53341 gattccaaaa atttatctat atcctccaaa aataattcta caggaatctt ttcatctgtt
    53401 gcatttcctc ctaaatcaac ccccattaag gaaacaaatc ttatattttt attgcttttt
    53461 aggatttctc ttaattcttc attagtgtgt ttatctttct ctattacgta taatagacta
    53521 tccatttttc cactctccca taatttttat gtatatttta ttttgttaaa tacaagataa
    53581 atttcatttt ccttacattc atgaattttt cttgcaaatt attcgtgttt tattcgtgtt
    53641 tttatttata ttattatata tcaagtataa aaagttcgca atatttttta ttggaaaaaa
    53701 tattatacat acaatagttt aacattttta caaatatggg gtatactaaa ataaaagtat
    53761 ttttatttga aaatttaatt ttatttataa tataatctat agtaaaagaa ataataaaaa
    53821 aatttaggag ataaacttta tggaatacat aattttcgat ttggaattta accaaggatt
    53881 tgataaaaaa ctcaataaaa ctgtatccaa tgaaaagtgt ccttttgaaa ttatacaaat
    53941 aggagcaatt aaattggatt ctaaattcaa tataatagat acgtttaata gctatgtaaa
    54001 acctacaatt tataaagaca tacatccctt tattagtcgt atgactaata ttaaaaattc
    54061 tgattttaat gattcgccta ctttccctga ggtctacaac aattttataa aatttatatc
    54121 atcacaagac cctatattat gtgtttgggg agttggagat ttaaaggaat tatacaggaa
    54181 tatcaactat cacaagctac catcaagttc cttacctaaa tcttatatta atatacaaca
    54241 acatgcatct aaatatttca ataatccagc aggaaaaagc attggcctac aaaatgctat
    54301 ttctatattg gaacttgatg aaaaaatgtc ttatcacaat gctttaaatg atgcatatta
    54361 tactgctaaa gtttttatta agatatacaa tccaagtata gtcccagata tatatcttta
    54421 tacgagtata aaacctaaaa ctataagata ttctaataaa aaaagagttg attatgataa
    54481 gttatttgat gaatttagga aaattttaaa tcgtgaatta actaaagacg agaaaaaaat
    54541 cattaactta gcttataata tggggaaaac aaatcaattt acattagaaa atgttaagca
    54601 aagaaaaaac aaatagagtt tatttagata aaaaataggc atgtagatta aaaaactagt
    54661 taactttaaa tttatatcta cagcccaatt tttatcgtaa ttaattttta ttttatctct
    54721 aattcaactg gacaatggtc tgaacctaat atttcagtgt gtatatccgc acttactaat
    54781 ctatcttcta attttttgga tgcacaaaaa taatctattc tccaccctgc attatttttt
    54841 cttgcattaa atctatatga ccaccaacta taaacgcctt ctttatcagg attaaaatat
    54901 ctatatgtgt ctataaaccc actgtctaat aatttagaaa acttctctct ttcttcttta
    54961 gtaaaacctg catttttcat attattttta ggatttttta aatctatttc tttatgtgca
    55021 acgttcatat ctccacacac aattacaggc ttatgattat ctagtttggt taaataatct
    55081 ataaagtcgt cttcccatct agttctatat tctagtctct ttaattcaga ttgagaattt
    55141 ggcgtatata ctgtaacaaa gtaaaaatct tcaaactcta gagttatcac tctaccctct
    55201 ttgtcatgtt cttctatatt tattccatac attactttta aaggctcttt ttttgtaaat
    55261 atagcagtac ctgaataacc ctttctctca gcataattcc aatattgaaa atatcctggt
    55321 aaatctaact ctatttgccc ttcttgcaat ttagtttctt gtaaacaaaa tatatctgca
    55381 tctacttctt tgaaaaagtc taaaaatcct ttcccaacac aagctcttat tccattaaca
    55441 ttccatgata taaatttcat acttatactc ctcatctaaa cattgacaca ctccccatag
    55501 ctaaagatgg gggcttttca acaattttat tgtaaattct taatttactt ttattttaac
    55561 aatactatac tataatttca tctataatta ctatttactt aatacctaaa aatatatgtt
    55621 ttaatcaatt tttaactttt ttgttaaatc ttcagggctc attgaagaaa catacatatt
    55681 tgttccaagt tcaaatcctc caaaattata ttttcttggg attatgtgca tatgaacatt
    55741 aaaatacgat tttgtttcaa tctttgttgg atgagtgtga atacataagt taaatggcat
    55801 atatccattg atattgtata acttcttaaa caacttttca aatattgtag aaagctcctg
    55861 tatattatta tcatttaact caccaaactc tattttatct ttaaatatta ttcttacttc
    55921 tccactatac ttggttgcat atggtataag taccaaaaaa gcttctccat tataaacaac
    55981 tcttctatct aaacttattt cattttctat taaatcatca tacaaagagc ttttattgct
    56041 gtcataatac tcctttgaaa ctaacagttc attcgtaatt tcaggtggaa taaaagacat
    56101 agacaatatt tgagcatgtg gatgcatcaa agatgctcct gcctttctca agaagttttt
    56161 gaagatacta acatactcta ctttatcatc tttcgacaaa tctctaaatc tatttctata
    56221 cataaaaaaa acatcttcaa attctttttg actcatgtta taaaaactac gattatgttt
    56281 atcgctctct atcattactt catgaacacc atatacatct cttgccatat catcaattat
    56341 aggaaattta ttgtagacag attttacaag ccatccttct tcactttcta tttcaaataa
    56401 tgcatcagtt gcatgagctt catttccttt gcaaaatggg cattcttcat catattcatt
    56461 agtttcttca tcttcatttg ggatatctgc tgtatctaaa ggtcttttta acctatctgt
    56521 agcaaatata acaacatcat tagtaattgg atctattctt aattctttca taattaacac
    56581 ctcttagtta atagccttta atataattat atgatattta tcgtatctgt taaataaatt
    56641 tataatattt tttataattt tgcatattta ttattatata ttttgtctat agctgaaaga
    56701 ttataactaa aaaatcacta tcagtgtatc agaatattat cttactataa attaatttat
    56761 gaatacataa tttagtggca taaacatggg tattttacta taatttgtta aaagtttatt
    56821 ttaaagctat attaattttt tttgatgatt tttacccata agtatgttat tattatcttg
    56881 taaagatgtc ttgtattcaa acatacaatt tacataatac aatatacgta tttaaattaa
    56941 atagggggta ttaaaatgaa ttattcaaac agagttagtg caatgcaagc ctctccaatc
    57001 agaaaacttg ttccatttgc acaagcagca aaagataaag gaatcaaagt atatcactta
    57061 aacataggac aaccagacat aaaaactcct aaaggatttt ttgatgctgt taaaaacttt
    57121 gatagcgaag tcttagaata tgctacatca gaaggtattc cagaattatt agaagcactt
    57181 caaaattact ataaaactta cgatatgaat tttgaaaaag atgaattatt agtaactaat
    57241 ggtggtagtg aagctttact tttcactatg atggcagttt gtgacccagg agataatcta
    57301 ttagttccag aaccattcta tacaaactac aatggatttg gtcaatctgt aaatgtagaa
    57361 gttaatgctg ttacaacaaa ggcagaaaac ggtttccacc ttccatctaa agaagaaata
    57421 ttgtctaaag tagatgataa aactaaggct ataattcttt ctaacccagg aaatccaact
    57481 ggtgcaattt atacaaaaga agaacttaat atcctagctg aaatagctaa agaaaaagat
    57541 ttatggataa tagcagacga agtttataga gaatttgttt atgatgggct tgagtataca
    57601 agctgtggta acttagaggg tgtacaggat agagttataa taatagacag tgtttctaag
    57661 agatacagtg cttgtggtgc tagaattggt tctatcgctt gcaaaaataa aggtcttatc
    57721 gctcaaatac ttaaattatg tcaaggaaga ctttgtgttc ctacattaga gcaaatagga
    57781 gctgttgagt tatacaaaac tcctgtttct tacttcaaag aagttaatga agagtacaaa
    57841 aaaagaagag atgtattata caatgaatta atgaaggttg aaggtgttat atgtaaaaaa
    57901 ccaactggtg ctttctatat agttgctaaa ttaccagttg aaaatgcaga agatttcaca
    57961 atttggatgt taaaagaatt taacaaagat aatgaaacag ttatggtttg ccctgctgaa
    58021 ggattctatg ctactccagg tttaggacgt gatgaaataa gattagctta catcttaaat
    58081 gaaaaagacc ttcatagagc tgctacatta ttaaaagaag gtttagagca atatgtagct
    58141 ttacaaaaat aattttttaa acttaattta tataaattta atgatataaa atgtcccctt
    58201 ttcagatatt atttgaaaag gggacatttc ttaattaata tattaattaa gacttagacc
    58261 tgactatttt tcattttctt tatatagtgt tggccagtaa tctttattca ctttaattaa
    58321 agcatctaaa acttgtcttg ccttagttgg agagattata gttctattta atgttaaaga
    58381 taaaatagct ttttcataag attgttcaaa gtatgcatca actgctaact tttcataagc
    58441 tagttgacct tctaacagtc ccttataaaa tgttggtata ttacctacat gtaaaggtct
    58501 cggtccattc tttgtaagaa tcgcagctac ttctaccatt gcatcatcag gtaagttgtt
    58561 aatagcccca ttattttctg ttataactat ggctatttgg tgtttgttat gagctattgc
    58621 ttctgcaact tcaactataa attccccatg agcatcatta tgcactaaat tagaacctat
    58681 agatgttcct ttttctataa cagatttaca ttcttcaaat acacgctttt ctcttccatt
    58741 cataacttct cttgctctag tacaatttat atttgattta gctacttttt tatcaggata
    58801 tagataatac tgtacatatg tattaggtaa gtaatctggt acatcttcca acatatcttt
    58861 aaccattcca taagtgtcta accaagattt atctctttgt tctgcatcaa caggttggaa
    58921 tccagagttt gctactaaat cttttatctt aggtaccaaa tcttcaccat ttttatcata
    58981 caaatgtgta aaccatccaa agtgatttaa tccaaagtat acaggctcaa atgttcttga
    59041 atccatgtct aacaatcttc cataagacct taacaagtta actggttggt cacacatatt
    59101 aagtaatctt ttatcatctg gaaatactct ttttaatgct tctgcaacaa tagcagcagg
    59161 atttgtataa tttaatatcc atgctttagg agagtatttt cttacagtct taaccatttc
    59221 tatcatatca cctatagacc ttaacccata agcaaatcca ccagctccac aagtttcttg
    59281 accaaccagt ccaaattgta gaggaatctt ttcatctaat tctcgcatct taagaccacc
    59341 agttctcatt tgaacaaata caaaatctac atctataaat gcttcatctg ggtttgtagt
    59401 atattcaagt gttgctttag gatattcttc tttaaataat atttttccaa attcccctat
    59461 taatctttga cgttcttcta ctacatctaa catagttact ttatttagag gaaatctatc
    59521 actcatttta cataaagact ttaaaagtcc tggagtccaa gtactgcctc ctccaactat
    59581 agctatattg tatctttttt tcattgtcat attaatcacc cctgtttttt attaactaac
    59641 ttgtaagatg attataatat ataaagtttt ctacatgaat acttttaggt aatcattaaa
    59701 aatagttcaa ttttagtatt tttttcaaaa ttgtaatttt tttcatctat tgtatttttc
    59761 aatgtattta tgaaacatat attccataag agaaagtgct ggcactctag acgtatagtt
    59821 aacactatta aaattatatt gtggagaaga tacaaataat tttatatcag ctatatttga
    59881 taatgaattg acacttatat ttgtcagaga aattacttta acttgatttg tttttgctat
    59941 attacatgcc ttaataactt gagcagtctc tccagacata gatacagcaa ttacaaggtc
    60001 atctttagta atatttgatg cagccaaata catgagagtt gaatcatcat agtattttac
    60061 atttacacct atagctgaaa aacgttgaga catttcagta catactaatc tagaagaccc
    60121 aacaccaaaa aaatatatat gcttagaatt atgtatttca tttaaacaca tatctatatt
    60181 ctctacattt attaaatttt gtgtatccat aacatcagta aaaatatcac tttgactttt
    60241 agtaaactcc ttatttcttt catttctatt tgaatatgaa aaaactaaaa agtttttaaa
    60301 ttcactatat ccagaaaagc cgagcttctg acaaaacctt actatgtatg cagtcgaatt
    60361 aaaagtttca tttgctatat ctttaatctt tttttgattt attttttcag aattttttag
    60421 aaaatagttt aaaagagata tttcatttgt agataatttt ttttgattta tatctaattt
    60481 gtctattagg ttcatttata cctccataat aatgatttgt agttaaacaa ctttctcata
    60541 tttattatat aaatatacac tatacaacat ttatcttatg tttattatac tacaaaaaag
    60601 acaatacaaa ttataaatta gtattgcctt ttaatattta cattagatag acattaaata
    60661 gacattgcaa aagaaacttc gtctcttact tgagatacag atggcccata aattatttgg
    60721 atatctttat cagatacttt tataacgccc attgcacctg tatatttttt aaaagcattt
    60781 tcatctactt tactcatatc tttaactact actcttaagc gagttataca gtttgttata
    60841 tcttctatat tctccttacc acctaaatat ttaattatgg ataatgctct cttagtagtt
    60901 tctccacttt gagctatttc tactttattt gataaaggtt ctaaatcaaa atttatatct
    60961 gttatttctt ctcgtcctgg agtttgtaag ttaaatctaa gtatcaaaac cttaaataca
    61021 ttataataaa ccagtgcata cactaaacca agtattatag aataaatcca ctttgtattt
    61081 ggttgcataa ctccaaatac tactaaatct attatgccac cttgagtatt tcctattgct
    61141 actccaaata tatgcatcat cataaatgat atacctgata aaaatgcatg tataacaaat
    61201 aatattggtg atacaaataa gaatgaaaat tccaatggtt ccgtaattcc tgttacaaat
    61261 gttgctaaag caccagctag taatatacct ttaaccttcg acctattttc aggctttgca
    61321 gttttataca tggcatatgc tgcagcagga agaccaaata ccattatagg tattttccct
    61381 tgagctaaaa atctagttgc ttctgttgaa aaactgattg tttcagggtc acttagttga
    61441 gctaaaaata tgttcaatgc tccaaatact tcttgtcctc ctacaactaa agaacctcct
    61501 acttcagtaa atctaaacat agcatttaat atatgatgta atccaaatgg tattaaaagc
    61561 ctttcaagaa atccaaatac aaaggttcct aaatatccta aactagctat accaatacct
    61621 acactctgaa taattgtatt tacatatggc catatatatg gtattattat ccccaaaata
    61681 gagaatacta ctgttgttat tattggaaca aacctagttc caccaaagaa ccctaaataa
    61741 tctggcagtt ttatattata gtatttatta tgtaatgatg ctgttattat accaactaca
    61801 attccaccaa atactcctaa ctctaatgtt tgtatgccta aagttacagc ttgacccatt
    61861 tctctcatca tgtcaggttc agcaagaata cctctacacc ctaacatata atttacacta
    61921 gtgtgtaata ctaaataacc aacaaaacca gaaaatgcag aaactgcttt ttcttcttta
    61981 gcaagaccaa cagatattga tatagcaaag aatattgcta agtttccaaa aagtactcct
    62041 gttatagctt ttgtaaaacc caatattcct tgaataaaat tattttctaa aaaaggtata
    62101 tcactaacta tattaggatt tgaaaatgct gaacttattc ctaaaaatat acctgcagca
    62161 gatattaatg ctattggcaa taaaaatgat tttcctaact gtaaaaaaaa ctctttcatt
    62221 ttttgtttca tttctatccc tccattttta aatttttaaa acgttttcta tgtcataatt
    62281 atatattttt attttgtttt tgaaacttta taatttgttt taaaatattt ttacataaat
    62341 agtaattttt tcaaaactgt aaattttttc aaacaaagac atagtaacat tgtgatatat
    62401 agaaatttaa aaagagatta gaaaataaaa ttattgaata taaaatggaa aaatataaat
    62461 tacacaaaga ggtatgagta ggtactaaca aataagaaaa tgtataagaa attataaaaa
    62521 agtacatcaa gaaaatttaa gatgtacttt ttagattgta tttagactta taattatata
    62581 gttaaatgaa taacaaagaa ttaatcttag tactattaaa tataaaaatt ttttatattt
    62641 tttctatcta aattcttctt tgtttaatat atattgaaga gtatttattg cttctaaata
    62701 tttttttctg tcttcttcag ttaatttaga aagtttttct cctaaaccat cacttaattt
    62761 atccataaaa tcagttgcta tcttatctcc ctcttcagta atgtcaatta gatattttct
    62821 tctatcaact aaatctcttt tccttgttac atacttctta tcagttaaat catcaaccat
    62881 actagttaaa ctgccttttt ctatatttaa cttagagcat aaatcagtca tacttattac
    62941 tccataattt tttatgaaaa ctaatgctct taattgtgtt ttatttacat tataatctgg
    63001 tgcaaatttt tttaggtctt ctaagtacag actagaataa atcttaggaa atgtttttac
    63061 taaaaaactt atggtatctt ttactatata gttcatataa tcacctcggt tgttttaaaa
    63121 tttattaaat tatctaaata actttatttc agtttacatt aaaaatattg caagtacaat
    63181 agtttttgct gaatgtttaa atttaattag taatcttatc atttttttat ttttatttat
    63241 attatttcta ttaaatatta tttatatagc tattttatta aattcatggt atagtaagta
    63301 aagaagaact cttcacagcg ctgaagagaa gacgctagcc cattaaaatg gctatcttat
    63361 ttataaataa gatagccgtt tttaattata ttttatctgt acaattctat actcttaggt
    63421 ccacatctac ttttcctaag tcttccttat aatcttttat agcaggttct acaacttcat
    63481 ttacaaattc tacaacttgt tctggagctc tacctataaa gttttttggg tccattatag
    63541 atagtatttc ttccttgctc attttaaatg aatcatcatt cattataagt tcaattaagt
    63601 tattatcctt accttcgtgc tttactctat aggcagcttt catagaatat tctcttatta
    63661 tttcatgtaa ttcctgtcta tctccacctc tttttacagc ttccataagt attgtttctg
    63721 tagccataaa aggaagttct tcatttacac gtttatttat catattttca tatactacta
    63781 aaccatcagt tacatttatc cctatttcaa gtatagcatc tgctgccata aatgcttgag
    63841 gtattgccaa tctcttattg gctgagtcat ctaatgttct ctctaaccat tgagtggctt
    63901 gtaccattgc agggcttata gattcagaga ttatatactt agataaagat gctattctct
    63961 cacttctcat tgggtttctc ttataagcca ttgctgatga acctatttga tttttttcaa
    64021 atggctcttc taattctttt aaactttgta aaagtcttat atcgttagtc atcttatgca
    64081 tactttgagc tatccctgat agtatgctta ttacttgata atctaacttt ctagtatatg
    64141 tctgtccact tactgcatag gaagaatggt atcccatctt tttacaaatt ttcttatcta
    64201 actcttttac tttttcgtgg tctccttcaa ataagcttaa aaaacttgct tgagtaccag
    64261 tagtaccttt aactcctctt aacttcatgt tatctattct atagtttaaa tcttccaaat
    64321 caagaattaa atcttgagcc cataaacaag ctctttttcc tactgttgta agttgagcag
    64381 cttggaagtg tgtaaatcca agagctggca tatctttgta cttaagtgca aattctttta
    64441 aattgtttat taaatttaca agctttactc ttagaagttt taaagcttca ttcatttgta
    64501 taacatctgt attatctcca acatatgcag atgttgctcc taaatgtatt attcctttgg
    64561 ctttttcaca ttgtaaacca taagctttta cgtgagacat tacatcatgt cttacttctt
    64621 tttctatttt tctagcttca tcaaaattta tattatctat attagctctt agctcatcta
    64681 attgttcttc agttatattg attcctaact catgttcacc ttctgcaagt gcaacccata
    64741 accttctcca tgtagagaat ttaaattgtg gagaaaatat ataactcatg tccttgctac
    64801 aatatctgtc tgtaagtggg tttgagtaag tagtatattt attatctatc attatattag
    64861 caccttcctt aaatcttttg tcgtgtgatt actgtgtaca cattagtaca taaataatta
    64921 tatataattt tacgaactat aacaagactt ttttattttt tgttcacatc tatatatagt
    64981 attttttatt tattactatt ttttatttat atccaaatta tctttttcaa ttaagtaatc
    65041 cactatttca ctatcaacaa aatttaatac atacttatat ctaattgcat agtatttatc
    65101 actccatcca agctgatttt ttacatcact ttcatctgcc ccaagcctta aacttattgc
    65161 tgcaaatgaa tgtctaaaat ctcttgctga atattgagaa agtccagcta aatctaatgc
    65221 ttttttgact ataagtctga catttctatc tgttatagaa ttactctttt gagttgtaaa
    65281 aataaaatca tcactaggta ttattacctc tggaagccca gaataattcc tgtaatcttc
    65341 taaaagttta aaaaagtatg gatgtaattt aactactctt tcttttcttc ccttacctaa
    65401 ccttacatat gagttatcgt tttcatctac cataaggtct ttccacttta agctaactaa
    65461 ttcatttaat aaacacccag tagtaactag acagactatt attactctat ctcttatatt
    65521 taattttggt aggataccta taagtttatt tatttcttgt atacttagaa catcatcttt
    65581 tgtttttatt cttgttactg tgggtttttc tacatatcta aatggattta tatctatgta
    65641 tccttctttt tttaagaagt tataaaaact atgtaaataa ctatatatct tttcacaagt
    65701 tgatttcgca tatttagtct gtatatagtc tacaaaattt ttacaatctt cttttgtagc
    65761 ataaatcaat tctttccctt ttaaaaattc tttaaacagt ataacctttg ataaataatc
    65821 gtgtttcgtg tttggattta attttgtaga aaaaacatta aaagtttcat actcataatc
    65881 atctagtatt tttgtactat acataataac tcctttcctt ttcataaaat aaaatagcta
    65941 tacttttact ataccatata tttccccctc aaatataccc cttattcaat agataacttt
    66001 taagtttatt ttgttatatt atgaaggttt tatgaaaata tcaatcttcc attgtgcact
    66061 acacagtact atggtattat aagttagtaa aaggtggcat ttttttatta atctatgaat
    66121 aaaatatgct actataaatt tgtattggag gtattttgat ttggaaacat ttagtttgct
    66181 tgaaattttt aaggcagtca ttttgggcat agttcaggga ataacagaat ggctaccagt
    66241 aagtagtaca gggcatatga tattaattaa tgagtttata aaattgaatt tttcaaatac
    66301 atttataaat acatttttag ttgtaattca atttggttca atactagctg tacttgttat
    66361 attttttaga aagttaaatc cttttgatag tgcaaagaat attaaacaga aaaaagaaac
    66421 agttcgttta tggcttaagg ttataattgc agttatacca tctggagtta ttggaatact
    66481 gtttgaagat gacatagaca gagtattctt taattcaaca gtagttgcta ttgctcttat
    66541 tgtctatggt ataataatga tagggcttga aaagagaaat aaaagaccta agtataaaga
    66601 tttttctcaa gttacatata aattagctct ttgtatagga ttattccagt gtctagctct
    66661 cataccaggt acatctaggt ctggttctac tataataggt gcagtattac ttggtacttc
    66721 tagatatgta gcagcagagt tttcattctt cttagccatt cctacaatgc ttggagctag
    66781 tgcattaaaa cttctaaaag ctggatttgg atttactgga tttgaatggc ttattttagg
    66841 tgttggttct gtagtagcat ttgttgtttc aattgtagtt attaaatttt ttatggacta
    66901 tatcaaaaaa catgacttca aagtatttgg ttattataga atagtcttgg gtatagtggt
    66961 tcttgcttat ttctttctat tataatgtat tctaatttaa taacaaatga taaggagaaa
    67021 agttatgagt gttaaaaaag aaatatttga ttggattaag tcaatagcta tggctattgt
    67081 acttgcattt gtaattctac aatttataag accttctgtt gtaagtggag aatcaatgta
    67141 tcctacttta gatgataaag attatctgat tttaaatagg atatcataca aggttggtaa
    67201 acctgaaaaa ggcgatattg tagtttttaa aaccaattta gttgatggag aaacaggaaa
    67261 gaaaaaagac ttaataaaaa gagttatagc tactgaaggt gacagaataa aaatatcaaa
    67321 ttctaaagtg tatgtaaatg gaaaattatt aaatgaacca tatatacaca ataactatac
    67381 ttctggagat atagatactg ttgttccaaa aggtaaacta tttgcaatgg gagataatag
    67441 agaaaatagt aatgatagta gattccctga tgtaggtatg gttgatgaag atgaaattct
    67501 tggtaaggtt atggtgagac tattacctct tgataatatt gggaaagtgg actaaaaaat
    67561 aagagactga attggtaaag tttattttac aaatctcagt ctctttttat tttcttaaat
    67621 tacaaatatt tttttactaa atatcttttg attctgtaat aagtcttatt atatcacttg
    67681 cttcttcatt aaaagttgtt actatactta ggtagtctgt tgctctactc atagctaaat
    67741 aaaccttatt taaatctcct acaaagtcat ttacttgata atcttgttca atatcattta
    67801 tagtttgatt gtataacatc tctaattcac atactattac cgctttatac tctaaattct
    67861 ttattgcata tatatttgct attgtagttc ctaccttctt acttatattt gtcaaattat
    67921 cttctgcaca tatataagga atttttgcct cttccaatgc tttttttaac atatattgaa
    67981 agtaaatggt ttttccactt tttaatttct tcttattata aggataaacg atagcaactt
    68041 cagaataatc aagacctttt ttacttatta aatactcaat ttcccagatt acagaactta
    68101 tttggtcatc aaggtcactt acttttatta tatcaacaga cttatttcca cctctaagtg
    68161 ctttagtata aaagaaagta ctaaattctg tatttggtct taattcgttg atatatgagt
    68221 tagaattatt tgaaaattta tttgtaaaat ctacaatctc tttagcttgt ctataatttt
    68281 tacttaagat aatcttatca tcaaattcta taccattata taatttttta aatatattca
    68341 atctattaga gatattcaag gagttacaag aacacacatt aaatatgaat tttgttttat
    68401 ataaaaactc ccttataaaa tctatttcat actctaaaaa gctttctgct tcatcaataa
    68461 aaatagcctt gaacatattt ttatttttta taatgttctg tgcttgtttt acaagattat
    68521 taaaggtctt ttcgtaatca ttttttaaca tgttataatc tacaattaaa ttgaattttt
    68581 tagctagttt aaatataaaa gaactaaatg tgtgaacttc taaattgtta ttatctttgt
    68641 ataataactc tatcctctct cgaagctcat tgcacaattg ttttgtatgt gtaaatatga
    68701 ctaatttatg atgtggatat acttttgcta attttatagc cctagaaagc ataattgctg
    68761 ttttgcctat accagaacca ccttcaataa gtgtattccc atatttaata gaaacaacat
    68821 ctttaatttg aacgtcttcc atcatagttg ctgtatactt atagtcatca ttgtagaatg
    68881 aaattttttt aaatttttca tttagatgaa gtttatcatt tattatatag tattctgaac
    68941 atatgtctag taaaaataaa tttaagttta tttcatcatt ctcatcatta agatactcct
    69001 ccagcgaacc cttattcatt atatcttgaa gcttattttt atctattata ttattattaa
    69061 caaattcttc aaattcatat gtttcctcaa cttcaacgta tggcataatg taaacgtagt
    69121 tataacttat atttctattc ttttgtccca tttttagttt caaaagttca tattcctcat
    69181 tcataacttc aagtaactct tcttctaaaa taaaaaatat atcttctgtt gtatccataa
    69241 attttataaa taaaattctt ccatctttaa catacaacaa atcggtattt attcctttaa
    69301 aaggagtaac ttttggcact actttaacgt cctcattgat attttcgtaa aatattttct
    69361 cgaactcctt caattttagg gcgtctaact gagaatttat atttatgtat tggctcactt
    69421 acattacctc cttctgttat acttaattat accattttga actatatttt tatatatact
    69481 ttttataggc aaatttagta aataaattca aaataaatac aaataaatac aaaactgcta
    69541 aaa
//
LOCUS       DAMJYN010000009        61863 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.009, whole genome shotgun sequence.
ACCESSION   DAMJYN010000009 DAMJYN010000000
VERSION     DAMJYN010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 61863)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 61863)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61863
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.009"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(123..1724)
                     /locus_tag="PC466_000697"
     CDS             complement(123..1724)
                     /locus_tag="PC466_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HDF2768120.1"
                     /translation="MIYDLILKNGFIIDGTGNPGFYGDIAIKDNLIAKIDSKINSNTN
                     KEIDCCGKVITPGFIDPHVHEEIVAILDGKFEKFLKQGVTTTINGNCGHSITPYSSEN
                     VYEYMYKNGLLLEEEKKYLIDKNKCWNNFTEYCDLISKSGISVNMGFLLGHGTIRWSV
                     MGGSKDRPPTEKEKNEITDIINDGMKSGAFGISTGLAYIPSKYADIDELVDIARQIKE
                     HDGIYTSHIRDYIGRYNAVKEAIEVGQKSGARVQVSHLSPVEIEAFDEILKARYNGVE
                     IMVDTVPRSSGHCMKKKRVIQFIMAISSSLFELGIDGVMDDLRNEEGRTLILKEAFIL
                     GDRGSIILLNTKDINMEKKSIREIATQKGIDEDKLLLDLLLDGDEELIFCLGGMYRAD
                     FPDKLHDNKIIDNPFVMVGSDCLFSVGGDMSWFELQRRGAFPIFFNMYRKSGVRLEEI
                     VRRVTSLPARQFKIKNRGIIKEGLIADIAVIDMDNYSYSRSEDIDFSKPQLLANGVEY
                     VIVNGKIALENGEITENKCGEVLKR"
     gene            complement(1835..2512)
                     /locus_tag="PC466_000698"
     CDS             complement(1835..2512)
                     /locus_tag="PC466_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768121.1"
                     /translation="MSKVKSIYNEEYLPFMIRYGRLTLSLGIIAALVPGIILSFGFGI
                     MPPISALLASTMAIVSMSAPNYIIEPVSYSPILGIPGTYMSFLSGNISNMRLPCSIAA
                     QKAAEVESGTEEGSIISTIGIAVSILVNISILTIGVILGGSVLSKIPAEVVEKLNLIL
                     PALFGSVFGQVFLQDKKLGLVAIVISVLTIILSKQGIIPQSLVVLICVFGTILIARAM
                     YKDKLSD"
     gene            complement(2525..3220)
                     /locus_tag="PC466_000699"
     CDS             complement(2525..3220)
                     /locus_tag="PC466_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5058 family protein"
                     /protein_id="HDF2768122.1"
                     /translation="MDYLKLANHPLLWIASTVAVSIVVVQSLIFAIKSCKVGKTMGIT
                     DKQIKSAVKSSAISAIGPSMTIFAGMVSLIVTMGGPIAWMRLSFIGSVIFESMSAGFG
                     TDALGITLGSPEMTKLAFTNAVWTMILGSLGWIIFTLLFGHKLDKITNVISSGKKSFI
                     PIISLGAMLGSFAYLNADRVLRFDNGTIACISGMAIMVILCMLEKKKNIKWLREWGLT
                     ISMFSGMIIASVI"
     gene            complement(3272..4471)
                     /locus_tag="PC466_000700"
     CDS             complement(3272..4471)
                     /locus_tag="PC466_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane dipeptidase"
                     /protein_id="HDF2768123.1"
                     /translation="MKSAYKGYEAYSYLEKGKDISSIEMCKGDKRVKEYLIELDDIQE
                     AKVKSIVDEKIFISLHEHPVLFPEHLERDIFEYNREGKQRCAYEALSRGYYDAIFDNL
                     MDGVCTITSNSGWKWDDILIDLGMRLCDLAHQDFVIKCEKVEDICRAKSEGKVALIPT
                     LEGAAPIENELDRIDILYGFGIRLMGITYSESNALGSGLKEEKDGGLTNFGKKAVERM
                     NKIGMAIDCSHVGVQTTLDVIEYSKDPIILSHVGARNLWNTKRLTPDEVLIACAKKGG
                     VIGVEAAPHTTITEKNKEHSIESFMEHFEYIKNLVGIDHVAFGPDTVYGDHVKLHSVL
                     AAKFDIKKITGTKEHPKVEYVKGLENPTETSKNIVRYLVKHGYSDEEIEKVLGGNILR
                     VLKQVWK"
     gene            complement(4732..6777)
                     /locus_tag="PC466_000701"
     CDS             complement(4732..6777)
                     /locus_tag="PC466_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2768124.1"
                     /translation="MKKHNILFVSTDDKINIDISKQLENIFGEFCNIDNLVYVNRINI
                     ELSSYELVVCSDNDIKEYIHNNIDKNILIVIVHRTINIENINQIISIENDSDVMVIDA
                     YKESADETAKIIRKLGLIHINLIPYYPGCDKSKCEIGIITGSRNSIPQNIKQIIDIGD
                     KVIDINTVIEIFTKLNISIDKLHIIKEKYNEDTVSGYRYYTTMNKTMKSFLEIIDEGI
                     ASVDKLGKFIYCNKVFSNLVGIDQNEIISNNFMDLFSDKVVKKIFFQEDEVNDEVVNL
                     NNKKLIINKVNVYENNERIKSIISIKNISAIQVLEDKIQNKLQSKGFVSKYTFESVVG
                     ESKIIKEKINIARKIATTDFSVLILGENGTGKEIFAQAIHNESLRKNKPFVAVNLSSL
                     SDTLIESELFGYDEGSFTGAIKGGKMGIFERAHTGTIFLDEIGDISLDVQQRLLRVLQ
                     EKEVMRMGGSKIIPIDVRIIAATNKDLKKKIKEGSFREDLYYRINVLHIEIPRLRERK
                     EDIPLISKYFLDEINSNKCFTEESMQALTLYEWPGNVRELKNLIYYIDTIVEEDRVDY
                     EHLPEQFRFEKNNTLVNENFDSIILDFKQSNFFEESICILNSIETWNNKNILLGRNKL
                     QEILKEKDIVLSVDQIRKRIDKLKSHGLLLSGVKKQGSFITDEGKNFISYVKIKGVI"
     gene            complement(7188..7997)
                     /locus_tag="PC466_000702"
     CDS             complement(7188..7997)
                     /locus_tag="PC466_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF2768125.1"
                     /translation="MYYVYVNDINIAVYDLNPSAKKTVLFIHGWPLGHKIFEYQTNIL
                     PKLGYRTVSIDLRGFGKSDATSGGYTYSQLADDIYKVVHAIGLKDFTFVGFSMGGAIV
                     LRYMSLFNGYGVSKLVLAAAAAPSFVQRPPEFPYGMTREDVNKLIAQACTDRPEMVTD
                     FGEKVFASNPPESFRRWFNDIGFSASGIGTIGTAVSLRDEELFNDLKCVRVPTGIFHG
                     KLDEICPYEFAVFMNEKIEDSILYTFEYSGHAIFYDELKLFNQEFLQFLEE"
     gene            complement(8081..8614)
                     /locus_tag="PC466_000703"
     CDS             complement(8081..8614)
                     /locus_tag="PC466_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HDF2768126.1"
                     /translation="MSDAHYDMHKRNGYSSDEPYPEIKVLGLNKYYAELLMDDYAGVS
                     SEFTSVNQYLYHNFDLDETHRELSEMWINISITEMLHMEILAKTIRLLGGNPVYRGST
                     SSCGAYWNGGFVCYGNSICNRLKLDLHLEHVAINNYYKDISLIEDPYIKAILNRIILD
                     EKLHVSLFEKAIEKYCK"
     gene            complement(8741..10816)
                     /locus_tag="PC466_000704"
     CDS             complement(8741..10816)
                     /locus_tag="PC466_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2768127.1"
                     /translation="MLKGLSFRNARRQAGKYLIYWCSLIGSVALIYAFNALIFSDVMQ
                     ELSSILNNGGSDEFSYMIIIFSFIITFILGWFVSYMMNFILKKRSREISTYMILGVDK
                     KQIVKMLFIENLLLGASALIVGWILGIFVSKVLESIVINMFHGKYSLSPDFSLKAAGM
                     TFLYFCIIYLIAQLKSNKKLVKMKLINLLNYDRYNENVLIHQTKTKSIMFCVSVLCGG
                     MGIFFFSIPSGRLTDVFLGLLLIVFCLIVLFMGFGSIAQNMFEKGMNWKYKKSHLFLY
                     RLLASKINGISIIMGIIATLFTVSIACIGIANSFYSVMNKSVDLQQFDVSIFHPNESY
                     DFSSYEGYLSETKGVKKDYSYTLYTEEKTSFMKVRNNILSKYLKDIGRDLQYKDYTFA
                     ENQFDTFMKYSDYNILRNMLGLNPIKMDKNQFIIHCMPYLADAYKNYIGEKYKLTISD
                     KDLSIAGIYIENFSQYGGYGNGQEYIIVIPDYLIDNMKPLYSLYVAITSEPLDSAYFT
                     EFQKKFDTLENLNSGVVVAGNQGFVSKLRYDNKDYISGKYAMQSTGQAIILILPLFYL
                     ALIICIIGTVILSIQLLSENNIIIKHYGMLRTLGMIDSEVIKILKKHVCLYFSIPLIP
                     AVIFGGILVSVFSYNMFNISFDAPVFFNIQIPILHAVAITLINFVVIYCIYVFITYVA
                     LRKEILHIK"
     gene            complement(10819..11565)
                     /locus_tag="PC466_000705"
     CDS             complement(10819..11565)
                     /locus_tag="PC466_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2768128.1"
                     /translation="MLLRVENIEKYYGNQKILTKALNDVSFQINTGEFVSIMGTSGSG
                     KTTLLNCIATIDTVSAGKIYLENQDITELSEENLTVFRRDNLGFVFQDSNLLDTLTLE
                     ENIALPLTIKKVSPVEITNSVYNIATQLKIEEILSKFPYEVSGGQRQRCAVARAVVTE
                     PKLILADEPTGALDSNSSKTLMELLETINTILEATILLVTHDAISASYTERILFLRDG
                     KIFNELRKGEKSRLTFYHEILDALSLMGGD"
     gene            complement(11579..11974)
                     /locus_tag="PC466_000706"
     CDS             complement(11579..11974)
                     /locus_tag="PC466_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase"
                     /protein_id="HDF2768129.1"
                     /translation="MKKRILTILCVVLVLFISITGLDSMGFFSRSIIPLRSEYASFIR
                     KNGTITEVKFTGPFNHNNIDLNKNVEDTNKNGDDNELTIKYDIEVKKSLISSNEPTIQ
                     IQDSKESIYVYILNFSDKTIIIKNGKIVD"
     gene            complement(12087..13109)
                     /locus_tag="PC466_000707"
     CDS             complement(12087..13109)
                     /locus_tag="PC466_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDF2768130.1"
                     /translation="MRFCNFLQDKVLVILLNICCAISLVLYLHLIGIGQGELTLLIAA
                     WVAILFCWICFCYQKQKKEIIKLRRIVDELDKKYLFIEMIEKPTSNIEREYYNIIRLS
                     LKSMTDHVSQIHREMYEYRQFIEQWVHEIKHPVTTSELICENYKNEHTRKIRFQMEEI
                     ERHIERALYYARLGHVEKDYLISEITLKSIVEEVLAKNKLLLIQNNIHINIQDLEYSV
                     YTDKKWIVFILNQIIINSVQYKSDSAEISFFAIKEDKSVKFTIKDNGIGIKESEIYRI
                     FELGFTGSNGRTTNNSTGIGLYLCYELSKKMGIDIDVSSSLGEYTAITLNFPINTAIN
                     MQKQCN"
     gene            complement(13106..13777)
                     /locus_tag="PC466_000708"
     CDS             complement(13106..13777)
                     /locus_tag="PC466_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005924879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2768131.1"
                     /translation="MILTNILIIEDDVFICKELMQFFENNGYSTQTLDTNNCDVLQVI
                     QESTPDLILLDINLPNIDGFSLCRQIRNCSTIPIIFITARDSAIDELNGLTMGGDDYI
                     TKPYNLPLLLARVKNLLKRVDSSDKQKIKYREIILNLISATVEYQNAVIELSRTELKI
                     MYYLFQNVGSIVPRIDLVEYLWDNHIHIDDNALSVNITRLREKLRGIGITDLIITKRG
                     MGYRI"
     gene            complement(13863..15212)
                     /locus_tag="PC466_000709"
     CDS             complement(13863..15212)
                     /locus_tag="PC466_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TldD/PmbA family protein"
                     /protein_id="HDF2768132.1"
                     /translation="MELKNFKDILFKKALSEGFEECEIYYYTGENLSINIYEGEVEKY
                     NLDKSFGLSFRGKVNGKIGYSYTEILDDKAVDMLIKNVKDGVNTIENEDVQFIYEGDK
                     HYNDVKTYSKELENLEADKLIDLALEMERETKAYSDKVVNLSKCTISYSVSSNGISNT
                     KGLNLSNKTNMLIGFVVPIIEDNGQKYDGIGYNRANSIEEIKPCEISKLGVDNALSKV
                     GGKSIPSGKYKTILLNEAMVSLLSTFSGIFNADSAQKGLSLLKNREGDMIASPIVTIV
                     DDPLLENGMASTPFDDEGVATFKKEVVLNGKLITLLHNLKTANKAGVKTTGNGIKSSY
                     SSPISIYPTNFYIDKGDKSLDEIIKDIDEGLMVTSFAGLHSGANSVTGDFSLAAKGFY
                     IKEGKKVFPVEQITVAGNYFDLLKDIEVIGEDLEFPMSSIGSPSVVIKELSVAGKDE"
     gene            complement(15224..16606)
                     /locus_tag="PC466_000710"
     CDS             complement(15224..16606)
                     /locus_tag="PC466_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011967718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TldD/PmbA family protein"
                     /protein_id="HDF2768133.1"
                     /translation="MLSKNIASKVLEKCLITGGDFAEIFEEDTINNSISLIDNKVENA
                     IGGRNYGIGIRIFKGLKSIYAYTSDNSLNSLLDVAYKAAVALGKLEDGKSVILNDSIK
                     INNIHNIKIYPNSIGNRDKVSVMKVAYKSAKEFSNDISQVSVSYLDKDQKILIANTEG
                     IYVEDRRIRTRLGISSIASKGNENQTGFEGPGGCKGFEIFEEIDPEYYAKESARVAHT
                     MLHAKNCPAGNMMVAIDNGFGGVIFHEACGHSLEATSVAKGNSVFADKLGQQIASTKI
                     TAIDDGTIPNYWGSMNIDDEGNPTQKNILIENGILKSYMIDKLNGRRMGMNPTGSSRR
                     QNYKFAPTSRMTNTYIAAGEDRPEDIIKSIPDGLYAKKMGGGSVNPVTGEFNFAVSEG
                     YLIKNGEIQEPVRGASLIGKGSDILMNIDMVGNNVKQAQGMCGSSSGSIPTNVGQPMI
                     RVKEITVGGR"
     gene            16850..18064
                     /locus_tag="PC466_000711"
     CDS             16850..18064
                     /locus_tag="PC466_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HDF2768134.1"
                     /translation="MNQEYVKGNPIFTNINKVPRQFPYLTDDIDTDVIIVGGGVTGCI
                     CAYYLAKNNIKSVILEKGRIAHGSTSVTTSLLQYELDDNLIDLTEVMTLKDALKAYNL
                     CTSALEELDTFIKLYGNKCDYAKRDTLLYTANKLEIKAIKEEYNLRKENGFDVEYIDE
                     STNPFSFDLKSGLIAKNGGRELDPYKYSHHLIDVSLKNGLQVYENTEVKKVDLSNDKV
                     TAEVSYGYKVHGKKLIVATGYNTSLFTKRNFATKSNTFNIATKPLKNIASWKNNILIR
                     DNCDPYNYLRTTKDNRLIIGGEDVSFDDIENETLANEKYDILEQRLKSMFKDIKDIEV
                     EYKYCGCFASTLDNLGFIGPDNKNNNLWYCLGYGANGILFAILGGIMLSELYLGKQNK
                     NMKLFKVDRFDK"
     gene            18241..20154
                     /locus_tag="PC466_000712"
     CDS             18241..20154
                     /locus_tag="PC466_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2768135.1"
                     /translation="MKYGGIIMKEILVIAPTKGTYEKSIHIVKKNKYTNIDVVFGNLK
                     EGIPLAEKSINHGTRIIISRGGTYNMLKATYNIPIVEIKVDAYDIIKSYKEVKNSNEP
                     FGIIGFNNVIYGFDIIEEILNKKITMIEIEKEEEIYDAIEKYRKKGINTYIGDTTVAH
                     IVKRLNCKGILIESREENILRAIQQAEQILEATKDEQKRRLQIEAMTDFVHDGIITVD
                     KNFKITLFNKSAEKIFGIKKENALYHNVVDVIPNTVLPQVVETMEPQIGEIQNIGSTK
                     IITNRVPIIVDGQIQGAVSTFQDSKEISSFEHTIRRSLLSKGLSAKYTFDNIIHASEK
                     TKDCIELAKKYACYDTPMIITGESGVGKELFCQSIHNYSKRKNAPFVAVNCAAIPPSL
                     IESEFFGYEEGSFTGARKKGKAGVFELAHEGTIFLDEISEIPLELQGRLLRVLQEKQV
                     MRIGGDKVIPIDVKIICASNKDLKNMMRNGLFRQDLYFRINILTLYLPSLKERKEDII
                     KLSEFFIHKYSSKYNKTPLIITPNIKKALLEREYEGNIRELEGMMERAVIVESFDSIL
                     LEKVSNEYTNNIVDKDNSDFECSNLDLKTLEKKYIYKIYNENNRNTTKTCEILKITRS
                     TLWRKLKEIEDDV"
     gene            20425..21399
                     /locus_tag="PC466_000713"
     CDS             20425..21399
                     /locus_tag="PC466_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-3-deoxygluconate permease"
                     /protein_id="HDF2768136.1"
                     /translation="MHILKSVKKIPGGLMVCPLLLGALFNTVCPQALEIGGFTTSLFK
                     TGAMSILALFCLCNGAQINIRQAGKPLTKGIVLTATKFIIGAVLGIIVSKFIGPKGII
                     GITPLAIVATMTNSNGGLFAALAGEYGDSTDVGAISILSLNDGPFFTMLAFGVTGLAN
                     VPIVALFAALIPILLGFILGNLDEDIREFLAPGTTLLIPFFAFPLGAALNFNQIITAG
                     LPGVVLGLGVTIITGMGGYFVMKLIRAEHPAVGAATGTTAGNAAGTPEALAAIDPTLA
                     TIAAVSTVQVAAAIIVTAICCPMLVSYLDKREKKKKSIFKTNKNIEVN"
     gene            21420..21695
                     /locus_tag="PC466_000714"
     CDS             21420..21695
                     /locus_tag="PC466_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HDF2768137.1"
                     /translation="MNAIIHANEKDNLVTCVRPLVKGEKVSIDGKSYIVNDNIPVFHK
                     MATEDVKKGDVVYKYGEIIGIATVDIKTGDYVHVHNIESTRGRGDKK"
     gene            21708..22871
                     /locus_tag="PC466_000715"
     CDS             21708..22871
                     /locus_tag="PC466_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HDF2768138.1"
                     /translation="MKLMGYLRENGQFGIRNHVLIIPTSVCSSETATRIASLVPGAIA
                     IPHQHGCCQIGSDIELTAKTLIGFGKNPNVAAVLVVGLGCDGIQAKELASEIATTGKK
                     VDYVVIQECGGTLKTVSKGTEIVSKMAREVSKEVRVEFGMSEITLALECGGSDPTSGI
                     ASNPSIGVASNLLVDEGGSSILSETTEVIGAEHLLATRFEDEEMKDKFLKFVSDVEKR
                     AIAMGEDLRSGQPTPGNKAGGLSTIEEKSLGCMYKAGNKPFKGALEYADIVPPDKKGL
                     YFMDTPGQDIDSITGMVAGGAQIVIFSTGRGTPTGSPISPVIKITGNSDTYNKMPDNI
                     DINAGRIITDGAKIADIGQEIFNEIIEVCNGKHTKAESLGHREFGIYRISSTF"
     gene            23208..25488
                     /locus_tag="PC466_000716"
                     /pseudo
     CDS             23208..25488
                     /locus_tag="PC466_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439637.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
     gene            complement(25583..26923)
                     /locus_tag="PC466_000717"
     CDS             complement(25583..26923)
                     /locus_tag="PC466_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF2768139.1"
                     /translation="MENQEALRHEKIWILLFRYSIPAIIAMMVTSLYNVVDRAFIGSM
                     EGIGSIAIAGLGVTMPVFTLIIAFGMLVSVGASTRLSIKLGERNREEAEKILGNALTL
                     SIIISLIITILGLVFLEDILFILGASKDSIFYAKDYMSVILIGSIFNLVAFSLNNAIR
                     AEGNPKLAARTMIVGCVLNLILDPIFIFVFNLGIKGAAIATVLCQIVVFFWVTYYFIR
                     GKSTLKLKKCNLKLNKDIVKKVFAIGMTPFAMEVAISITHMFTNNSLKVYGGDLAIGA
                     MTALTSILLMFMMPVFGLNQGMQTIISYNYGAKQYERAKKTLILSIIVSVVILSFGFL
                     IVQVFPEVFVGIFNKDSDLMDIAVRGISINLITLPIMGISIVGPVYFQCISKVKHSMF
                     LTLLRQFILFIPLIIVLPIQFNLDGVWLAQPVADFIAMIIVLLFLKREFKTSRV"
     gene            complement(26935..27717)
                     /locus_tag="PC466_000718"
     CDS             complement(26935..27717)
                     /locus_tag="PC466_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004460318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2768140.1"
                     /translation="MNCINTKNLNVSYGNTDIIKNLNLNIPKGKITTIIGANGCGKST
                     ILKTIGRIISPNSGKIYINGEDIYKKKSKEIAKDMAVLPQSPQAPSGLTVSELISYGR
                     FPHKSGFGNSSKEDREIVNWSLEVTGIAEFKDRNMEDLSGGQRQRAWIAMALAQETDI
                     LLLDEPTTYLDLAHQLEILKLLDELNKKQGRTIVMVIHELNNAARFADHMIGIKKGKI
                     VCEGDAYDVMTKDNLKELFNIDAEIATDPRTNKPICITYDMV"
     gene            complement(27732..28754)
                     /locus_tag="PC466_000719"
     CDS             complement(27732..28754)
                     /locus_tag="PC466_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HDF2768141.1"
                     /translation="MKNIIKINSKTLLVISILMVLIFITFLLSLNMGSFSIEPMDVIK
                     TFLGQGQRNHEIAIFKLRLPRIVIALLVGSALSTAGVILQGVTKNDLADSGILGINSG
                     AALFVVVYIYLMNGNVYEGMSNLTVFTMPIVALIGALFGAFLIYSLAWKGGINSSRLL
                     LIGIGVNIAFTSILTIFQLKFTTQEFNRVMAWTSGSIWGTSWKYVIAVLPFIVIFMGI
                     TIYKSKYIDVLNLGDEVSISLGVDVEKQRRRLIIYAVILSGVSTAVAGSISFLGLIAP
                     HIGRKIIGPKHKRLIPVSALIGTLLLLIADTISRNLLAPIEIPVGIVVSIIGVPYFIY
                     LMLVND"
     gene            complement(28760..29773)
                     /locus_tag="PC466_000720"
     CDS             complement(28760..29773)
                     /locus_tag="PC466_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HDF2768142.1"
                     /translation="MTKLSKKNITYLLILVSIVVLVFGIVLSITIGAKDMNLSTVIDS
                     LIKMEDGINMRIVKDVRLPRAIAAALVGGFLAVSGAIMQGITRNPIAEPSVIGITQGA
                     TFAISISLVLQKKLPQLIHGSFSVMMFAFIGASISGLFIYFISSKSRGRVNNVKLALA
                     GVALGTLLISLASAISMYFNLSQQLSFWISGGLVGVKWEGIKLLFVAGGIGFILAIIM
                     APRITILSLGEEVAIGLGQKTNFVRFICIVLVILMTGASVSVSGNIIFIGLIVPQIAK
                     GIVGSDYKYIIPSSLVLGAVLLVYTDILSRMINPPYETPVGSITALIGVPIFIYLVRK
                     GEK"
     gene            complement(29901..30839)
                     /locus_tag="PC466_000721"
     CDS             complement(29901..30839)
                     /locus_tag="PC466_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF2768143.1"
                     /translation="MKKIKSLAIFISIITTLVLVTACSDKNTEDKDKSETRVVQSVKG
                     EVKIPSNPKKIVDISGSSEELLLAGYKPVATANVDSYETDKLPSYIREELKGVKIVGH
                     SMMDTMDMEAILEVNPDLIIMSQRQEKIYDQLKEIAPVVMMKDYANDWRSKLTDVSKL
                     FDKEEEAKSWLQKYDEKATKLGKEVIEKNGEKTYLPVLASSGQFMVFSDGGIGTLIND
                     DMKLARPKNMPKQDGITLPMVSMEGLTDIDADHIVVIATEADKKDLENSAIWSQIRAV
                     KDGNVTILDAAPFFSQSYNPIGKELLLESVKNELTK"
     gene            31109..31573
                     /locus_tag="PC466_000722"
     CDS             31109..31573
                     /locus_tag="PC466_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016208838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768144.1"
                     /translation="MVHLVYCDNAGKKGEKVLDKILAGTKTMVIRGAAGRKIPHSRVF
                     EDELLYFMEKGTGKISAKATVKKVENYVKLTEDEISKILNENQPKLNLSEKQKVRWHK
                     KCLCLVEFENVEEITPLDFDHQGNMDDWLIVEKIEDVVVGTSIPYNYEKSKF"
     gene            complement(31685..32002)
                     /locus_tag="PC466_000723"
     CDS             complement(31685..32002)
                     /locus_tag="PC466_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HDF2768145.1"
                     /translation="MDEKMIEISFGIIGFAGDAKGLAFEAIKEAKSGNIDKARECIEK
                     SKESIHKAHKFQTELIQNEANGNKTEISVILIHAQDHLMTAMNFQQLAEEFIDVYERL
                     ESK"
     gene            complement(32015..32746)
                     /gene="chbG"
                     /locus_tag="PC466_000724"
     CDS             complement(32015..32746)
                     /gene="chbG"
                     /locus_tag="PC466_000724"
                     /EC_number="3.5.1.105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chitin disaccharide deacetylase"
                     /protein_id="HDF2768146.1"
                     /translation="MTKIIINADDFGYCEAVNYGIISAHNNGIVRSTSMMANMPGVEH
                     GVGLLKENKTLNCGVHMTLSCGRPLLSNLKTIVDKDGFFIRRITDEIIEKMDCDEIYR
                     ELCAQIDRVKGLGIDISHLDSHHHIHTLVSLKPVVEKIVTKYNLPIRGGFEYNLEYSK
                     VVPLIDSFYKENVSEEYFIKNIDEIMKYDVVDIMSHPAFLDDYILNSTSYAIDRTKEH
                     KILTSKKVKEFLEKNGLVISSYRDI"
     gene            complement(32772..34082)
                     /locus_tag="PC466_000725"
     CDS             complement(32772..34082)
                     /locus_tag="PC466_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HDF2768147.1"
                     /translation="MKKGLKIVTIGGGSSYTPELVEGFINRYEELPVKELWLVDIEAG
                     KEKLEIVGNLAKRMVKKAGVDMKINLTLDRREALRDADFVTTQLRVGLLDARIKDETI
                     PLSHGVMGQETNGAGGLFKALRTIPVIFDIIKDVEELCPNAWMVNFTNPTGIITEAVF
                     KYTNFRRYIGLCNVPIHLKNDVAKLFNVESDRISMDFAGLNHMVYGLNVSLDGEDVTK
                     EAIDKFVKADISMQNIKAIDFNAEFVKSLGAIPCPYHRYYYKTKEMLEDELREFKEGK
                     ARGQVVKELEEQLFELYKDEKLDVKPPQLEKRGGAYYSDAACNLISSIYNDKKDIQVV
                     NTLNNGSIRDFKDEQAVEVSSVITKNGPKPISIGYLPDSVHGLVSQIKSFEVLVAKAA
                     VYGDYESALLALCINPLIPSDDLAKTILDEMLEAHKDYLPRFNR"
     gene            complement(34159..35472)
                     /locus_tag="PC466_000726"
     CDS             complement(34159..35472)
                     /locus_tag="PC466_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF2768148.1"
                     /translation="MEKFMSFMDKYIVPVAAKIGAQRHLVAVRDAFIVMIPITMVGAL
                     GTLINNLPLEAYKNLMASIFGENWTTFGGDLWWGAIGTMAVFLVIGVAYFLAKSYESD
                     GLQSGLIALSIFFIMAPQIGKIVPEGGTTVVEGWGMIQQTYLGTAALFSSILIGLLST
                     EIFVRLSKVKKLTIKMPDGVPPAVSRSFAKLIPGMLTIMIFTVIGIFIKMLSNGSFLT
                     DILNTYLGAPLSNVADSLGSTMLIAFIIHILWTVGLHGANIALPFTETILMKLGGENA
                     ALAQAGATEGYHVLAGAFFDAFVYLGGSGMVLGLIVALLIAGRRRKEMIVLGGPPAIF
                     NIGEPLIFGLPIVLNPIFMIPFVLAPVICSAVSYLAIDFGLVAPVILPKIPWVTPPIL
                     GGAMATGDWTGGALALFNLILSILIYIPFVIASEKMEANKLKINN"
     gene            complement(35494..35805)
                     /locus_tag="PC466_000727"
     CDS             complement(35494..35805)
                     /locus_tag="PC466_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2768149.1"
                     /translation="MIKIMLACSAGMSTSLLVTKMEDAAKENGIEAKIWAISEVNLKN
                     EIENCDVLLLGPQVRYVLGKATEMAKPYNIPVEVINMMDYGRCNGKAVLDRAVELNSS
                     K"
     gene            complement(36005..36709)
                     /locus_tag="PC466_000728"
     CDS             complement(36005..36709)
                     /locus_tag="PC466_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2768150.1"
                     /translation="MKEPIYKVIENHVRELINSDSLKEGDLIPSEKQLSEEFNVTRMT
                     VRSALNNLVKEGYITRQRGVGSIVIANNIYDNISSVSGFTKEMESKGYKVSNILVSLE
                     IVQADENLSSKLNISLEENVWEIKRVRLANDARVSYMITYMPVKLFPNLNKTHCENSL
                     YNFVEEVCGYKIAMSEREVQAVISNEECMDNLKLEEPEPLLYISQICKLQNSEIFEYS
                     HTYHYGYTLTLNAVVE"
     gene            complement(36804..38165)
                     /locus_tag="PC466_000729"
     CDS             complement(36804..38165)
                     /locus_tag="PC466_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF2768151.1"
                     /translation="MKDRINLTEGRITEKLLKLSLPIMGTSFIQMGYNMIDMIWVGKA
                     GSKAVAAVGTAGFFPWLAMAFIMISKVGGEIKVAQSIGANNISTTKSYMKSAIEINII
                     LAIIYTISLIVLNKQLIGFFRLGDLEVITMSRQYLIIVALGMVFYFINPVFTAIFNGL
                     GNSKTPFRINTVGLITNIILDPILIFGWGFAPKLGVAGAAIATVFAQIVVTTCFIYII
                     VKSKEEYFKLRLFKEIETKYYKVLYKLGLPIAIQSGMFTVFSMLLGVIVASWGPVAVA
                     VQKVGSQIEAISWMTAEGLSVALGSFVGQNYGAKKYSRINKGCKIAITVSSVLGIITT
                     LVLVFAGESIFSIFIDESEAIEKGAIYLKILGYSQFFMCLEIITTGAFKGLGRTYIPS
                     IIITILTGARVPLAYFISRPEMLGLNGVWWSITLSSILKGILMISLFISLLKLGKLYK
                     MSE"
     gene            38664..39809
                     /locus_tag="PC466_000730"
     CDS             38664..39809
                     /locus_tag="PC466_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDF2768152.1"
                     /translation="MKINKKFNRVDMQVSILTAIIVIISSSCVYFFNYTLTYKSMIYS
                     LSERSKHIYEYVERNIDKNTFTEINSKEDQSKKSYKSSKILLESVKNTTGVMYLYTAK
                     KTKDGSLVYVVDGLNSSRSDFRNAGDLIEKEIWGDLNKALDNHILLPKKIKSTSWGYI
                     FISYFPIHNDVGKVVGVIGIEFEAKHQYNTFKFISIVTPIIALLTCLISALIAVILFK
                     RISNPTYTDFANTDYLTGLKNRNAFEIDMNNLNNSNLKNLISIISIDLDGLKKINDKF
                     GHQTGDLYIKQASKIIQDVINKKYIVYRIGGDEYIIILKNLSHKEINSIINNINLKIV
                     EENSTNELKLSMSIGYAIFDEKVDVSLFDTYRRADSQMYDNKKKINK"
     gene            complement(39899..41617)
                     /locus_tag="PC466_000731"
     CDS             complement(39899..41617)
                     /locus_tag="PC466_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     permease subunit"
                     /protein_id="HDF2768153.1"
                     /translation="MNNNAISSKSISLKSKMNLDIKKCMLTVLVMSLVIFLLAPIIYL
                     FVQAFLDKDGVFVGLQNFQEYLASESLLNSLKNTVFVSVISTVISLTLALVYAYALTR
                     TKIKFKGFFKSLAMFPMFAPTMMHAIGLVYLFGNQGLVTNLLGVHVPIYGAVGIILAQ
                     IIYVFPQSFQILYISLSSTDYRLYEASNTMGISKIREFISITIPSIKYSLISSAFVSF
                     TLCFTDFGAPKVIGGEFNVLSIDVYKQIIGQQNMPMGATVSILLLIPAIISFIVTKKI
                     EKNQNSYITSKSIPYKVKTNKLRDSILGGVVGIIAFGIIAVMLTVILSSLISVWPYDL
                     RLTLEHFSMKNSIDGIKPFINSIKMSLLTAILGTSFVFLFAYLNEKTEKAPYLKSFGY
                     FLSTLPMALPGLVLGIAYVLFFNKLEFNFMDTIYIKNLFNGLYGTLLIMVICNIVHFF
                     SVAFITATTAIKKVDKELDMVAKSMGINSASILKNVTIPLCLPAVLENFMYFFLNSMV
                     TISALVFIYTASSKVAAISIVQLDDKGSTAQAAALAVLILVTNILVKVIYEFIKNRLE
                     KRTNFN"
     gene            complement(41622..42611)
                     /locus_tag="PC466_000732"
     CDS             complement(41622..42611)
                     /locus_tag="PC466_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF2768154.1"
                     /translation="MSYLKINNVFKSYDQKRVLNNISLDIEEGEFLCLLGPSGCGKTT
                     LLRIIAGLEDVNSGTIILQDKDITNLEPSKRGFGIVFQSYALFPNMTAYNNIAFPLKE
                     RKVSKEKIDNKVKEVLETVGLTNEAHKYPKALSGGQQQRIAIARALALEPKFLLLDEP
                     MSALDAKVRHKLRMDIKRLQKELNITTIMVTHDQEEAITMADKIAILNGGDIMQIGTP
                     EEIYQNPQNLFTAQFIGDTNCFDNGDSILTVRPEYVQIEKSTKENYQGIISNIEFRGN
                     LLRVEIKDKLNENFIISDVSIKEWVNLNLVEGDLVKISIDEKYYLKYPKVKGA"
     gene            complement(42707..43756)
                     /locus_tag="PC466_000733"
     CDS             complement(42707..43756)
                     /locus_tag="PC466_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HDF2768155.1"
                     /translation="MKEFIFTCLCIVVITFMTSCISTTPQTTQGKGNNKLTIYAALEE
                     EQIAYYMEGFREEYPNIDVEIVMDSHGVIASKLLAEKDNPQADIIWGLSAMNMIELKK
                     DGALEAYKPKNYDKVDKKFKDTEDDVSWVGMSVPETAIVVNYKELKKLGIDIPKSYED
                     LIKPEYKGLITMPNPASSGTGYLTVSGLIQMMGEKDAYNYMDKLHKNIATYTHSGSKP
                     AKLAGSGEYPIGITLGYRATQQLSSGEPIEVVFPKEGSGWDLEANALVKKDNIKKEAK
                     LFLDWAISDSAMDRYAHEVAVTSIKTYNPVPKGYSKQPFEQLIKEVDLNSAAKNRSTV
                     LKTWESKYGSKSESK"
     gene            complement(44033..44701)
                     /locus_tag="PC466_000734"
     CDS             complement(44033..44701)
                     /locus_tag="PC466_000734"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HDF2768156.1"
                     /translation="MARLNINPTRMEMTRLKKLLKTATRGHKLLKDKLDELMKQFLEI
                     VRENKRLREEAENALDTAYKNFIIARAVMSQEYLGSALMMPKQSVSVDVSTRNIMSVD
                     VPVFDFKTENNQSDIYPYGLAFTSGELDSAMEAFSDAMQPLLRLAESEKSAQLLAQEI
                     EKTRRRVNALENVMIPNYIETIKYIAMKLEENERASTTRLMKVKDMVLKKALEEKKKN
                     DLVV"
     gene            complement(44707..46080)
                     /locus_tag="PC466_000735"
     CDS             complement(44707..46080)
                     /locus_tag="PC466_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HDF2768157.1"
                     /translation="MIKEYKSIQEVAGPLMLINGVEGVKFDELGEIELSNGEIRRCKV
                     LEVNGDTALVQLFESSTGINLAESKVRFLGKSLDFGVSPDILGRVFSGMGRPIDGGPE
                     IIPDKRLDINGAPINPAARDYPAEFIQTGVSAIDGLNTLVRGQKLPIFSGSGLPHANL
                     AVQIARQAKVRGTDSKFAVVFAAVGITFEDAEFFISDFKATGAIDRSVVFVNLANDPA
                     VERVSTPRMALTAAEYLAFEQDMHVLVIITDITNYAEALREVSAAKKEVPGRRGYPGY
                     LYTDLATMYERAGKMKGHEGSITMIPILTMPEDDKTHPIPDLTGYITEGQIILSRELY
                     KKDIQPPIDVLPSLSRLKDKGIGKGKTREDHADTMNQLFAAYSRGKDAKELMAILGES
                     ALSEIDLMYAKFADEFEKEYVSQGFRTDRTIEQTLEIGWKLLSMLPKSELKRIRDEYF
                     EKYMPKE"
     gene            complement(46077..47855)
                     /locus_tag="PC466_000736"
     CDS             complement(46077..47855)
                     /locus_tag="PC466_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HDF2768158.1"
                     /translation="MKTGTIVKVSGPLVVAEGMRDANMFDVVRVSDKHLIGEIIEMHG
                     DKASIQVYEETSGLGPGEEVVSLGMPMSVELGPGLISTIYDGIQRPLEKMYDISGTNI
                     TKGVEVSSLDRTTKWEFKPKKSVGDKVVAGDIIGGVQETAVVECKIMVPYGVKGTIKE
                     IYSGEFTVEDTVCVITDEKGNDIPVTMMQKWPVRKERPYREKKTPDSLLVTGQRVIDT
                     FFPITKGGVAAIPGPFGSGKTVTQHQLAKWADADIVVYIGCGERGNEMTDVLLEFPEL
                     KDPRTGESLMQRTVLIANTSDMPVAAREASIYTGITIAEYFRDMGYSVALMADSTSRW
                     AEALREMSGRLEEMPGEEGYPAYLGSRLAQFYERAGKVNCLGMDEREGTLTAIGAVSP
                     PGGDTSEPVSQATLRIVKVFWGLDASLAYKRHFPAINWLTSYSLYQEKVDVWADKNVN
                     DNFSAQRAQAMKLLQVESELQEIVQLVGVDSLSDGDRLILEVTRSIREDFLHQNSFHE
                     VDTYTSLHKQYRMMGLILKFYKSAQDAIKQNVTINDIIKLSVLEKIGRAKYVEEGDID
                     AAYDSIEDEIDNELADLIKKRGAEEL"
     gene            complement(47972..48295)
                     /locus_tag="PC466_000737"
     CDS             complement(47972..48295)
                     /locus_tag="PC466_000737"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HDF2768159.1"
                     /translation="MLMYKVGVVGDKDSIMGFLALGIDIFPAYDSDEIKKSIHKLVED
                     EYAIIYITEQASLLAKESIAKYKDYQLPAIIVIPGIGGSMGLGMNEVRESSKRAIGAD
                     ILFKE"
     gene            complement(48282..49259)
                     /locus_tag="PC466_000738"
     CDS             complement(48282..49259)
                     /locus_tag="PC466_000738"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit C"
                     /protein_id="HDF2768160.1"
                     /translation="MAEEKTYPYAVARIRVLEKQLLNRQMFIQMAEAKSPEDSLRIIA
                     EAGYADTSNNNIHNFENILTQELSKTYEILKSLAPEEKFVDVFLYKNDYHNLKVLIKE
                     EISGVDGEKYLIDGGTIPLIKLRESLANRSFSDLPKIMSSAILEAFDVYNKTQNGQMV
                     DIVLDKATFTSMKETAKESQNKFVIDYVMKVCDLTNLKSFIRVKNMKKDFDMFMNVFV
                     SGGSLDKEKFLEAFSSDTPASCFKSTSYSDVCKNGMDSGFTVFEKLCDDYLMEYVRGA
                     KFKPLTLEPLIAYLYAKESEIKTIRIILTSKLNNIDADTIKERLRDAYV"
     gene            complement(49274..49837)
                     /locus_tag="PC466_000739"
     CDS             complement(49274..49837)
                     /locus_tag="PC466_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit E"
                     /protein_id="HDF2768161.1"
                     /translation="MGNEQKMIDRIIADAKQEAQEILDKAKSEADLKVNSANEKAEKE
                     MASYTKLAEAEAEKAASKEISGAYMEAKKQILSKKQEILEEVILEAKNKLLNLKDNEY
                     EEIILNMIEKSNCTDDSEIVLSKKDKKTLKDVLSKKGIKVSDETRDITGGFIVKKGDI
                     EYNYSFEAIIAVEHEYIEQIAAEILFN"
     gene            complement(49889..50380)
                     /locus_tag="PC466_000740"
     CDS             complement(49889..50380)
                     /locus_tag="PC466_000740"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HDF2768162.1"
                     /translation="MEFLNALGNGQFLAISGAAIAALFAGMGSAKGTSIAGQAAAGVV
                     TEDPSKFGQLLVLQLLPGTQGLYGFIIAFLILSKAGIIGGDAIPTSAQGLQLLMAGLP
                     IGLVGLVSGIAQGKAAAAGVGIVAKRPEELGKAITFAAIVETYALLGLLVSFLAYNGI
                     AIG"
     gene            complement(50383..52308)
                     /locus_tag="PC466_000741"
     CDS             complement(50383..52308)
                     /locus_tag="PC466_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HDF2768163.1"
                     /translation="MAIVNMNKISIVGLEAQKSQILKLLMNRGFVQIDDSAFLTEEEE
                     LKNYLVKDSEESEVIMLEQKMSHVNQAINIVSSLVKQKKSLLAPKREFNKIDSEKEGQ
                     VYAEALELNNLHKEIGTIRSNINLLNNNKSMLEPWVNFDIPLENMETKYTKTILGTVP
                     ISANIDALRVKLEDEIPESVIGIVNSDKLMNYVYLITLKETFDDVLEVLKEFNFSVVS
                     LPNEEGTPLQAIKKYNEMIIRQENVSKDKTEEIKRHADSIHMLENLYDFYTIERDQKK
                     IIERLVKTKTTFCLNGWLPSKRADELIKEITEKFDCCVQTEEGSKEEGFPILLENNKL
                     VTPFESVTNMYSYPSTKDIDPNTILTFFFVVFFGMMLSDAAYGLIIAVVCGFVVYKLK
                     IQKGEGNLIKLIGICGVSTTVWGLIFGGILGDLIPIKALINPLEDVMTLMGMSLLFGI
                     IHIYVGLGIKAYTLIRSGKVIDAIFDIGFWYLCITGVCLLIIPFVAGDIGVFSEVGKY
                     LAIIGAIGLVLTQGRSFKGIPVKLFKGFSSLYGITSYFADILSYTRIMALCLTTGVIA
                     QVINLLGAIAGPILAVVIGVVGHTINLLINALGAYVHTSRLQYVEFFNKFYEGGGVPF
                     VPFKYKTKYTSINKKEM"
     gene            complement(52310..52621)
                     /locus_tag="PC466_000742"
     CDS             complement(52310..52621)
                     /locus_tag="PC466_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768164.1"
                     /translation="MAFEIIKSIVEAEQTADSIKVKAVTDAESIRADAVNKCESIFAD
                     VRKQAKLMEETLIEKAVTDSRAEVDKILANAKSECLKIEKTAEERKSKAIEAVIGKVV
                     R"
     gene            complement(53251..53526)
                     /locus_tag="PC466_000743"
     CDS             complement(53251..53526)
                     /locus_tag="PC466_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif11-like leader peptide family natural product
                     precursor"
                     /protein_id="HDF2768165.1"
                     /translation="MNEKLTKILEEAKNDDEFRKELIKTREQRDVMDSFCKVVTSRGY
                     DITVGELFSMGEEYTSNLLKSVNGGAAYPIEDWSDWYEDFFIMLSNI"
     gene            complement(53641..55050)
                     /locus_tag="PC466_000744"
     CDS             complement(53641..55050)
                     /locus_tag="PC466_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase/peptidoglycan binding
                     protein"
                     /protein_id="HDF2768166.1"
                     /translation="MIDGKEVKQESGQKNLKFKIAIVVGVLFVAYIGMAIFFRNHFYF
                     GTTINGVKASGKTVEQVNDLLTSSTNSYTLNLEERNNKKEQIKAKDIDLKFTPDDKVQ
                     KIKDSQSAIGWIGGIFKSKEYNNMITLSYNKDLLEKRFNALSCFDSKNVVEPKSAYPK
                     YDSTKNAYVIVPEVLGNKVKKDDFYKLVQNSINSGNTSISLDESKVYEAPNNTKDSEK
                     LKQAIKTLDKYVGVVVTYDFSDRKETLDGSEINKWLKVDSEKNYDITFDNDAMVEYTR
                     SLSKKYSTFGDSRPFKTATGKDITISGGIYGWLIDKKKEAEALVDVVKAGKNVTREPI
                     YIQKAVSRNKDDIGNTYVEISLSGQHMWFFKNGEMLVSTDVVTGDLARGFATPSGIYP
                     LNYKARNVSLTGQGYSSPVSYWLPFNGNIGIHDATWRNSFGGGIYKSSGSHGCVNTPF
                     SKAKKIYENIEPGTPIILY"
     gene            complement(55420..56082)
                     /locus_tag="PC466_000745"
     CDS             complement(55420..56082)
                     /locus_tag="PC466_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768167.1"
                     /translation="MIDVSIDDKLKERWPNAKLGCIQAKVAVNKSSEKLINEINEFCD
                     TINQSLKVEDITKLDKIKDARNAYKELGKNPSRYRTSSEALVRRIIQGKGLYTINNIV
                     EINNLISIKSLYPVGTYNVSKLHSPVCFTVGDEGEQYKGIGKELINIENLPILSDSVG
                     KFGSPTSDSERAMITEDANEILICIFSFSQESDIEEYFGYAKELLKEYADGKDIETKI
                     IK"
     gene            complement(56336..58555)
                     /locus_tag="PC466_000746"
     CDS             complement(56336..58555)
                     /locus_tag="PC466_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDF2768168.1"
                     /translation="MTGRNKSFTLITILFLTSLFLTMGYIYIEDTKHLLMSEAKIHIK
                     EVAVQGSQLAQRQIEKDLDVLNIFSNYYALNQDIPNEEKMKNLLDEMENQKFYTMAIV
                     DINGNAENTKGDKFSVKDREFFKNSIKGKKYVSSPYVDEVNKSIKKITISVPLLNNDK
                     VVGVLYCTYNINTLMKLINVSFYENNSISYVVRNDGTIILHPQEDSLSKNIYKLLKQD
                     NDIREINRLKKELQENKTGATVLNMLEERRYLGYATMDNGNSENNYIKDWNLIFSIPE
                     TVVFSNSEQIINRAIYAVLFIILIFIAIIFYIIYIKKSNEKEILSLAYEDKVTHIGNQ
                     NKFYRECSKYLLDKPSLNYIIVYFDINNFKMINDTFGYEFGDNLLITIAKALKEELTE
                     GEVYARLSSDYFAIFCDYKNGKNKRIRKIDSIRNNIESNLSIVFEISLCVGIYFVEEG
                     EVDIQKAVNKANMARSVAKGKNINYAIYNEDVRNKLSEESMILDDIKIALVKNQFEVY
                     YQPKFSLVTGEMIGSEALIRWNHPEHGFISPAVFIPIAEKSKLILKIGRFVFERVCND
                     LSEWKKQGKKIVPVSINLSRVELYQPDIVKFINKTIQMYNLSSDLIEIEITETVAINE
                     LNILKNVLNELRKYGFSISMDDFGTGYSSISCLRDMPIDILKLDKSFLNGIEHDERSR
                     NIAKSIVSLAKSLDLVVIIEGVESKEQAELMKQFGCDLVQGFYFARPMPAKNFLDLL"
     gene            complement(58831..61485)
                     /gene="adhE"
                     /locus_tag="PC466_000747"
                     /gene_synonym="adhC"
     CDS             complement(58831..61485)
                     /gene="adhE"
                     /locus_tag="PC466_000747"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HDF2768169.1"
                     /translation="MAHKEQVIIENKKENEVMSVGLDTVNNVESLVKKLAKIREAQKI
                     FATYTQEQVDKIFLAASLAANKQRVPLAIMAQKETGMGIAEDKVIKNHYASEYIYNAY
                     KETKTCGVIEKDEAFGMTKIAEPIGVIAAVVPTTNPTSTAIFKALLALKTRNGIIFSP
                     HPRAKNSTIEAAKVVLEAAVLAGAPEGIIGWIDEPSLELTTTVMKEVDLTLATGGPGM
                     VKSAYSSGKPAIGVGAGNTPAIIDESADIKTAVNSILVSKTFDNGMICASEQSVIVLE
                     NIYNEVKKEFKERGAYLLDKDETEKIRNIILVNGGLNSKIVGQTACTIAKLAGFEVPV
                     DTKVLIGEVESVEIEEAFAHEKLSPVLAMYKASDFDNAVRKAEKLVEDGGFGHTSSLY
                     IDDVNQREKLDKFTSAMKTCRILINTPSSQGGIGDLYNFKLAPSLTLGCGSWGGNSVS
                     ENVGVKHLLNIKTVAERRENMLWFRSPGKVYFKKGCLGVALKELKDVMNKKRAFIVTD
                     TFLYNNGYTKAVTDLLDEMNIKHTTFFEVEPDPTLECAKIGAKAMREFNPDVIISIGG
                     GSAMDAGKIMWTLYEHPDVDFQDLAMRFMDIRKRVYTFPKMGEKANFVAIPTSAGTGS
                     EVTPFAVITDQDTGVKYPLADYELMPNMAIVDSDMMMNMPKSLTSASGIDALTHALEA
                     YVSMLATDYTNGLALQAIKSIFEYLPRAYDNGAKDPEAREKMANASTMAGMAFANAFL
                     GVCHSMAHKLGAFHHVPHGVANALLITEVMKFNSSDAPKKMGAFSQYKYPEALKRYAE
                     IASFLGLKGNSDEEKFQSLLVAIEDLKLKVGIPKSIKEFGVEEPKFMDSIDEMVIQAF
                     DDQCTGANPRYPLMNEIKDMYLNSYYGR"
BASE COUNT        20681 a        10760 c         7436 g        22986 t
ORIGIN      
        1 taaaataaat attaatacta taaataaaaa cgaagcatga tttttattta aataaatccc
       61 aaacttcgtc tttacttact tagatattta tttactttct aaatcctatt atttttaaaa
      121 ccttatcttt ttaatacttc accacattta ttctcagtaa tctctccatt ttctaacgca
      181 atttttccat ttacaattac atattcaaca ccattggcta gtaattgtgg ctttgaaaaa
      241 tcaatatctt ctgacctaga ataactatag ttatccatgt caataactgc tatatcagct
      301 atcaaccctt ctttaataat acctctattt tttattttaa attgcctagc tggtaatgaa
      361 gtaactcttc ttacaatctc ttccaatcta acaccagact ttctgtacat attgaagaaa
      421 attggaaaag ctcctcttct ttgtagttca aaccatgaca tatccccacc cacactaaac
      481 aaacaatctg aaccaaccat aacaaatgga ttatcaatta ttttattatc atgtagttta
      541 tctgggaaat cagctctata cattcctcct aaacaaaaga taagttcttc gtctccatct
      601 aaaagtaaat cgagtaataa cttgtcctca tctattcctt tttgtgtagc tatttcacgt
      661 attgatttct tttccatatt aatatcttta gtgtttagaa gtattatact ccccctatct
      721 ccaagtataa atgcttcttt taatataagt gttcttccct cttcatttct aagatcatcc
      781 attaccccat ctatacctaa ttcaaataga ctagatgata ttgccataat aaattgaatt
      841 actctttttt tcttcataca atgcccagaa cttcttggta ctgtgtcaac cattatttca
      901 acaccattat acctagcctt taatatctca tcaaatgctt ctatttcaac tggacttaag
      961 tgagatactt gaaccctagc accacttttt tgcccaacct ctatggcttc ttttactgca
     1021 ttatatcttc ctatgtaatc tctaatatga gatgtatata taccatcatg ctctttaatc
     1081 tgccttgcaa tatcaacaag ttcatcaata tcagcatact tacttggtat atatgccaat
     1141 ccagtagata ttccaaaagc accacttttc attccatcat ttattatatc tgtaatttca
     1201 tttttttcct tttctgtagg aggtctatcc ttagaacctc ccataacact ccatcttata
     1261 gtcccatgcc ccaacaagaa tcccatattg acagaaatac cacttttaga tataaggtca
     1321 caatattctg taaaattatt ccaacattta tttttatcta taagatactt tttttcttct
     1381 tcaagtaata gaccattttt atacatatat tcatatacat tttcagaaga atatggtgtt
     1441 atagaatgtc cacaattacc atttatagtt gttgtaactc cttgttttag aaacttttca
     1501 aatttaccat ctagtattgc tactatttct tcatgaacat gagggtcaat aaatccaggt
     1561 gttataactt ttccacaaca atcaatctct ttatttgtat tgctatttat cttagaatct
     1621 atttttgcta ttaagttgtc tttaattgct atatctccat aaaaaccagg attacctgta
     1681 ccatctatta taaatccatt ttttaagatt aaatcatata tcaaaatatt ccctccttaa
     1741 aaaccaattt ttaaataatc ttaatgtaat ttttatattt gaaaatcaaa ttattatatt
     1801 tcatatttga aaattcacta ttatttcatt gtaattagtc actaagctta tctttataca
     1861 tagctcttgc aattaatata gtaccaaata cacatataag aactactaga gactgtggta
     1921 ttataccttg ctttgataat ataatagtca atacagatat tacaattgct actagaccta
     1981 attttttatc ttgtaaaaat acttgtccaa aaactgaccc aaatagagct ggtaaaatta
     2041 agtttaattt ttctactact tcagctggaa ttttagataa tacgcttcct cctaaaatta
     2101 cccctatagt tagtatactt atattcacta aaatagatac agctattcct attgtagata
     2161 ttatcgagcc ttcttctgta cctgattcaa cttctgctgc cttttgagct gctattgaac
     2221 atggtagcct catattagat atattaccag aaagaaaact catataagtt cctgggatac
     2281 ctaagattgg tgaataagaa actggttcta ttatgtaatt tggagcactc atactgacaa
     2341 ttgccattgt acttgctaat aatgctgata ttggaggcat aataccaaat ccaaagctca
     2401 aaattattcc aggaactaat gctgctataa tacctaaaga tagtgttagt cttccatacc
     2461 ttatcataaa aggtaaatat tcttcattgt atatagattt tactttactc ataaaactcc
     2521 ccccttatat tactgaagct attatcattc cgctaaacat tgatattgta agcccccact
     2581 ctcttaacca ttttatattt ttcttctttt caagcataca caatattacc attatagcca
     2641 ttccacttat acatgcaatt gttccattat caaaacgcaa caccctatca gcatttagat
     2701 atgcaaatga acccaacatt gctcctagag atattattgg tataaatgat ttcttgccac
     2761 tagatataac attggttatc ttatctagtt tatgtccaaa tagtaatgtg aatattatcc
     2821 atcctaaaga acctaatatc atagtccaaa ctgcatttgt aaatgcaagt tttgtcattt
     2881 caggagaacc taaagttata cctaatgcat ctgttccaaa tccagctgac attgattcaa
     2941 aaattacaga acctataaat gataatctca tccatgctat aggcccaccc atagttacta
     3001 taagcgatac cattccagca aatatagtca ttgaaggccc aatagctgaa atagcactac
     3061 tcttaacagc tgactttatt tgtttatctg ttattcccat tgttttacca actttgcaag
     3121 attttatagc aaatataagg gattgtacca ctactattga tactgctact gtactcgcta
     3181 tccacaaaag tggatgatta gctaatttta aataatccat ttataaaacc tccctataaa
     3241 tcctcaaatt ttattaatat ttctaatata tctatttcca aacctgtttt agtactctaa
     3301 gtatatttcc acctagtacc ttctctattt cctcatcact atatccatgc tttactaaat
     3361 atctgacaat gttttttgaa gtttctgttg ggttctcaag accttttaca tattctactt
     3421 tgggatgttc ttttgtacct gttatttttt ttatatcaaa tttagcagct agtactgagt
     3481 gtaattttac atggtcgcca tatactgtat ctggtccaaa agctacatgg tctattccta
     3541 ctaaattttt aatatactca aaatgttcca taaatgactc tattgaatgt tctttattct
     3601 tctctgttat tgtagtatga ggtgctgctt ctacacctat aacccctcct tttttagcac
     3661 atgctattaa tacttcatct ggagttagtc tctttgtgtt ccataaattt cttgccccaa
     3721 catggcttaa tattattggg tccttgctat attctattac atcaagtgta gtttgaactc
     3781 caacgtgaga gcaatctatt gccattccaa ttttattcat tctttcaaca gctttttttc
     3841 cgaaatttgt aagacctcca tctttctctt cttttagtcc tgaacctaat gcattggatt
     3901 cgctgtatgt tatacccatt aaccttatac caaatccata cagtatatct attctatcaa
     3961 gttcattttc tattggtgct gcaccttcta atgttggtat caatgctact ttaccttcac
     4021 ttttagctct gcatatatct tctacttttt cacactttat gacaaaatct tgatgagcta
     4081 aatcacatag tctcatgcct aaatctatta atatatcatc ccatttccac cctgaatttg
     4141 atgttatcgt acatacacca tccattaaat tatcaaatat agcatcataa tatcctcttg
     4201 ataatgcttc ataagcgcat ctttgtttac cttccctatt atattcaaat atatctcttt
     4261 ctaggtgttc tggaaataat actggatgtt catgtaatga tataaatatt ttttcatcca
     4321 ctatactttt aaccttagct tcttgaatat catctaattc aataaggtac tctttaactc
     4381 ttttatctcc tttacacatc tcaatagatg aaatatcttt tcctttttct aaataactat
     4441 aggcttcata tcctttgtaa gctgacttca taacaacatc ctccaagttc tacaattttt
     4501 tatatttttc ctatgtagca attgatatgc caaaatataa attttaattg tataataaat
     4561 cttgcaaaaa ataaaaacag tagtaaggtt gatatttact actgttttat taaaaataat
     4621 cttcttagat tatttattca atatttttga attatcttaa tcttaaagat aattttattt
     4681 atttctatcc attataggga tttttttagg gtgttttgcc tttttagtcc cctatatcac
     4741 tcccttaatt tttacatatg atataaagtt ctttccttca tcagttataa aactaccttg
     4801 tttttttact ccagataaaa gtaaaccatg gctctttaac ttatctattc tttttctaat
     4861 ttggtctaca cttaaaacta tatctttttc ttttaaaatc tcttgcagtt tatttcttcc
     4921 taataatata tttttattat tccaagtttc tatactgttc aatatacata tactttcctc
     4981 aaagaaatta gattgtttga aatctaagat aattgaatcg aaattttcat taactaaagt
     5041 attgtttttt tcaaatctaa attgttctgg caaatgctcg taatctactc tatcttcctc
     5101 aactatagta tcaatataat aaattaaatt tttaagctct cttacatttc ctggccattc
     5161 atacaatgtt aaagcttgca ttgattcctc tgtaaaacat ttgttgctat ttatttcatc
     5221 taaaaaatac ttacttataa gaggtatatc ttccttacgt tctctaagtc taggtatctc
     5281 tatatgtaat acattaatcc tataatacaa atcttctcta aaagaacctt ctttaatttt
     5341 tttctttaaa tctttatttg ttgcagctat aattctaaca tctattggta taattttact
     5401 tccgcccatt ctcataactt ctttttcctg taatactctt agcaatctct gctgtacatc
     5461 taaagatata tcacctatct catctaaaaa aattgttcct gtatgcgctc tttcaaatat
     5521 acccattttt ccacctttta ttgctcctgt aaaacttcct tcatcatagc caaaaagttc
     5581 actttcaata agtgtatctg acaaagaaga tagattaact gcaacaaatg gcttgttttt
     5641 tcttagagat tcattatgta ttgcctgggc aaatatttct tttcctgttc cattttctcc
     5701 aagtatcaac acagaaaagt ctgtagttgc tatttttctt gcaatattaa ttttttcttt
     5761 tattatttta ctctcaccta caacactctc aaatgtatac tttgatacaa aaccttttga
     5821 ctgaagttta ttttgaatct tgtcctcaag cacttgaatt gcacttatat ttttaatgct
     5881 tataatactc tttattcgtt cattattttc ataaacattt actttattaa ttatcagttt
     5941 tttgttattt aaatttacta cttcatcatt aacttcatct tcttgaaaaa atattttttt
     6001 gacaacctta tcactaaata agtccataaa gttattagat ataatttcat tttggtctat
     6061 tccaactaga ttagaaaata ctttgttgca atatataaat tttcctaatt tatcaacaga
     6121 ggcaatacct tcatctataa tctccaaaaa actcttcatg gttttattca tagttgtata
     6181 atacctatat ccacttactg tatcttcatt gtatttttcc ttaataatat gtaatttatc
     6241 tatagatata tttagttttg taaagatttc tataactgta tttatatcaa ttaccttatc
     6301 acctatgtca attatttgct ttatgttttg tggtatgctg tttctgcttc ccgtaataat
     6361 tccaatctca catttagact tatcacaacc tggataatat ggtattagat taatatgaat
     6421 taatcctagt tttctaatta tcttggcagt ttcatctgct gactctttat aagcatctat
     6481 aaccataaca tcagaatcat tttctatact tattatctga tttatatttt caatatttat
     6541 agtacgatgt actattacaa taagtatatt tttatcaata ttattatgta tatattcctt
     6601 tatatcattg tctgaacata ctacaagctc atagcttgac agttcaatat ttatcctatt
     6661 tacatatacc aagttatcta tattacaaaa ttctccaaat atattttcca attgttttga
     6721 tatatctata tttattttgt catcagttga tacaaataaa atattatgtt ttttcatagt
     6781 cccacctcct gtttaacgag tatagaaagt aataatttgg tctattgtag cactttttaa
     6841 aaaagtttta aatcttaaaa atcaaatttt gtaccattta ctattatttt ccataataaa
     6901 ataatgtaag ctatcttttt tcacatataa tttaatttct aaaacggtta gtttgacatt
     6961 attggaatat aaacaaaaat ttaatataaa ttcgttaata tattaataca tttttaagaa
     7021 tgacaaggaa taaattataa caaattttag gaatatataa taatagggtc tcagaactta
     7081 gttacaagtt ctaaaaccct atttgtttag tgtaaaaaac atcataaaat ttagcttaaa
     7141 tcttttcaca taatattact ctttttctaa gtgataataa aatatatcta ttcctctaaa
     7201 aactgtaaaa attcctgatt aaatagttta agctcatcat agaatatagc atgaccacta
     7261 tactcaaaag tatataaaat tgaatcttct attttttcat tcataaaaac tgcaaattca
     7321 tacggacata tttcatctaa tttcccatga aatataccag taggcactct tacacatttt
     7381 aaatcattaa ataattcttc atctcttaaa gatacagcag ttccaatagt gccaatacct
     7441 gatgcactaa aaccaatatc attaaaccat cttctaaagc tttctggtgg atttgatgca
     7501 aatacttttt ctccaaaatc ggttaccatt tctggtctat cagtacatgc ttgtgctatc
     7561 aatttattta catcttcacg tgtcatacca tatggaaatt ctggaggtct ttgtacaaat
     7621 gatggtgcag cagctgcagc taataccaat tttgacactc catatccatt aaataaactc
     7681 atatacctaa gtacgattgc tcctcccatt gaaaaaccaa caaaggtaaa gtcttttaat
     7741 ccaatagcat gtaccacctt ataaatatcg tctgctaatt ggctataagt atatcctcct
     7801 gatgttgcat cagatttacc aaaacctctt aaatcaattg aaactgttct atatccgagt
     7861 tttggcaata tatttgtttg atattcaaat atcttatgtc ctaagggcca accatgtata
     7921 aaaagtacag tttttttagc actcggattc aaatcatata ctgctatgtt tatatcattc
     7981 acatatacat aatacatatc aacagcaact cccttcaaga aaatgtatga tggttatttt
     8041 atatatatga ataaaatgat gaataactaa atttttaaat ttatttacaa tacttctcta
     8101 ttgccttttc aaataaactt acatgaagtt tttcatctag gattattcta tttaatatag
     8161 cttttatata agggtcttca ataagactta tatctttata ataattatta atagccacat
     8221 gctccaaatg caaatctagt tttaatctgt tacaaataga atttccataa catacaaaac
     8281 caccattcca atatgcacca caagaacttg tagaacctct atatacagga tttccaccca
     8341 ataatcttat agtctttgct aatatctcca tatgtaacat ttctgttata gatatattta
     8401 tccacatttc acttaactct ctatgcgttt catctaaatc aaaattatgg tatagatatt
     8461 gatttacact cgtaaattca cttgatactc cggcatagtc atccatcaat aattctgcat
     8521 aatacttatt tagacctaaa acttttatct ctggatatgg ctcatcactt gaatatccat
     8581 ttcgcttgtg catgtcgtaa tgtgcatcac tcataatatc tcctccttta aatttaatac
     8641 ttgatattaa ttgtatgcat cacgactttt tcatataact tagataataa aatctattat
     8701 attattttct attataattt atgtgtcaat tcacccaaat ttatttgata tgcaatattt
     8761 ctttccttag tgctacatat gtaataaaaa catatataca atatattact acaaaattaa
     8821 taagcgtaat ggctacagca tgtaagatag gaatctgaat attaaaaaat actggagcat
     8881 caaaagaaat attaaacatg ttgtatgaaa aaactgatac caatattcca ccaaatatta
     8941 ctgcaggaat taatggaatc gaaaaatata aacaaacatg tttctttaag atttttatta
     9001 cttcactatc aatcatcccc aaagttcgaa gcattccata gtgttttatg ataatgttat
     9061 tttcgctcaa taattgaata gagagaatga ctgtaccaat aatgcatata atgagtgcca
     9121 aataaaaaag tggtaatatc aagataatgg cttgaccagt agattgcata gcatactttc
     9181 cacttatata atccttatta tcatatcgta atttagaaac aaagccttga ttacctgcta
     9241 ctactactcc agaattaaga ttttctaaag tatcaaactt tttctgaaac tcagtaaaat
     9301 aagcactatc caaaggctca cttgtaatag caacataaag actatacaga ggtttcatat
     9361 tatcaattaa ataatctgga atgacaataa tatattcttg tccatttcca tatcctccat
     9421 actgtgaaaa gttctctata taaatacctg caatacttaa gtccttatct gatattgtca
     9481 gtttatattt ttctccaata taattcttat atgcatcagc aagataaggc atacaatgga
     9541 tgataaattg atttttgtcc atctttattg ggtttaaacc caacatattt cttagtatat
     9601 tgtaatcact atatttcata aatgtgtcaa actggttttc tgcaaaagta taatccttat
     9661 attgtaaatc tcgccctata tctttcaagt atttagaaag gatattatta cgaaccttca
     9721 taaaggatgt tttttcttct gtgtaaagag tataagaata atcctttttc acacctttcg
     9781 tttctgataa atatccttca tatgaagaaa aatcatatga ttcattcggg tgaaaaatac
     9841 tcacatcaaa ttgttgtaaa tccactgatt tattcatcac agaataaaat gagttagcta
     9901 ttccaataca agcaattgat actgtaaaaa gagttgcgat aatacccatt ataatgctta
     9961 ttccatttat ctttgaagcc agtagacgat acaaaaataa gtgagatttc ttatatttcc
    10021 aattcatccc tttttcaaac atattctgtg caatagatcc aaatcccata aataatacga
    10081 ttagacaaaa tacaatcaac aataaaccaa gaaatacatc tgttaatcta ccactaggta
    10141 ttgaaaagaa aaaaataccc atacctccac acaaaacaga cacacaaaac ataatagact
    10201 tcgtttttgt ttggtgaatt aatacatttt cattatatcg atcataatta agcaaattaa
    10261 ttaatttcat tttaacaagt tttttattac tttttaattg agcaattaaa tatattatgc
    10321 agaagtataa aaaagtcatc ccagcagctt ttaatgaaaa atccggagat aaagaatact
    10381 ttccatgaaa catattaata acaatagatt ccaaaacctt agaaacaaat atccctagaa
    10441 tccatccaac aataagagca gaagcaccta ataaaagatt ctctataaaa agcattttaa
    10501 caatttgttt tttatctact cctaatatca tataagtact tatttctctg cttctttttt
    10561 tcaatataaa attcatcata taactaacaa accagcctaa aataaaagta ataatgaacg
    10621 aaaatatgat aatcatataa gaaaactcat cgcttcctcc attattaagt atactagaaa
    10681 gttcttgcat tacgtcggaa aatatcaaag cgttaaaagc ataaatcaaa gctacagagc
    10741 ctattaagga acaccaataa ataaggtact ttcctgcttg tcgtcttgca ttacgaaaag
    10801 ataatccttt caacataatc aatctcctcc catcaaagaa agtgcatcca aaatttcgtg
    10861 atagaaagta agtctggatt tttctccttt tctaagttcg ttaaaaattt tcccatccct
    10921 tagaaataaa attctctcag tataactagc tgaaatagcg tcgtgtgtga caagaagaat
    10981 cgtagcctct aatatggtgt ttatagtttc caaaagttcc attaaagttt tagatgaatt
    11041 agaatccaat gcaccagttg gttcatctgc caaaataagt ttgggctctg ttacaactgc
    11101 acgagctact gcacaacgtt gcctctgacc accagatact tcataaggaa acttcgaaag
    11161 tatctcttca attttcaatt gtgtggcaat attatacaca ctattagtaa tttcaacagg
    11221 agaaactttt tttattgtaa gtggaagtgc tatattttct tctaatgtca gagtatctaa
    11281 taaattagaa tcctgaaaaa caaaacctaa attatcacga cgaaaaacag ttaagttttc
    11341 ttcggatagt tcagtaatat cttgattttc aagataaatt tttccagcac ttactgtatc
    11401 aattgtagca atacaattta acaaagtagt tttaccagag ccagaagttc ccataatact
    11461 gacaaactct cctgtattaa tttgaaatga cacatcattc aaggcctttg taagtatttt
    11521 ctgattgcca taatatttct caatgttctc tactcgtaat agcatgttaa agtcctcctt
    11581 agtcaacaat ttttccattt ttaattatta ttgtcttatc tgaaaaattc aagatatata
    11641 catatatgct ttctttagag tcttgaattt gaatagtagg ttcattagat gaaattagag
    11701 atttttttac ttcaatatcg tattttattg ttaattcatt atcatctcca tttttattag
    11761 tatcttctac atttttattt aaatcaatgt tattatgatt aaagggacca gtaaacttta
    11821 cttctgtaat agttccattt tttctaataa aagaagcata ttcagacctt agtggtatga
    11881 tacttcgtga gaaaaaaccc atcgaatcca atcctgtaat tgaaataaac aaaacgagta
    11941 caacacataa tatagttaat atcctttttt tcatatgttt ctccctcctt tctattgata
    12001 ttgtagcgta aatagtaatc tgaatatata gaagttactt aactttatct tacagttttg
    12061 aaagataaag aaatagcagc gcatttttag ttgcactgct tctgcatatt gatagctgta
    12121 tttattggga aattcaatgt tattgctgtg tattcaccaa ggctggagga cacatctata
    12181 tcaattccca ttttcttaga cagttcataa caaaggtaaa gaccaatccc tgtagaattg
    12241 tttgtagtcc ttccattact gccagtaaaa cctaattcaa aaattcgata aatttcactt
    12301 tctttgatgc caataccatt atcttttata gtaaacttaa cactcttgtc ttcttttatt
    12361 gcaaaaaatg aaatttcagc tgaatcactt ttgtactgaa cactattgat aataatttga
    12421 tttaaaataa aaactatcca ctttttatca gtatatacac tatactccaa atcctgtata
    12481 ttaatatgaa tattattttg tataagaagc aatttattct ttgctaatac ttcttctaca
    12541 attgacttta atgttatttc agaaattaaa taatcttttt caacatggcc aaggcgagca
    12601 tagtacaatg cacgctcaat atgacgttct atttcttcca tttgaaaacg aatttttcgt
    12661 gtatgttcat ttttataatt ttcacatata agttctgatg ttgtaacagg atgttttatc
    12721 tcatgtaccc attgttcaat gaattgtcta tattcgtaca tttcacgatg tatttgagaa
    12781 acatgatctg tcatagattt caatgataat ctaataatat tgtagtattc acgttctatg
    12841 ttagaagtag gtttttcaat catttcaata aacagatatt ttttatccaa ttcgtctaca
    12901 atgcgacgta acttaataat ttcttttttc tgtttttgat aacaaaaaca tatccaacaa
    12961 aataaaattg cgacccaagc ggctataaga agagtcaact ctccttgacc aatccctata
    13021 agatgaagat atagcactaa tgaaattgca caacaaatat ttaagagtat aactaatact
    13081 ttatcttgaa gaaaattaca aaacctcata tcctatatcc catcccccgt tttgtaatga
    13141 ttaagtcagt aatacctata ccccttaact tttctctaag ccttgtaatg tttacactta
    13201 aagcattatc atcaatatga atatgattgt cccataaata ttctaccaaa tctatacgag
    13261 gcacaatact ccctacattc tgaaacaaat aatacatgat ttttagttca gttcttgaaa
    13321 gttctataac agcattttgg tattctactg tagctgaaat aaggttgagt ataatctctc
    13381 tatatttaat tttctgttta tctgatgaat ctactctttt aagtaggttc tttacccttg
    13441 ctaaaagcaa aggtaagtta tatggttttg taatatagtc atctcccccc atagtcaaac
    13501 catttagttc atcaattgca ctatctcttg ctgtaataaa aataataggt atagtagaac
    13561 aattcctaat ctgtctacat aaagaaaaac catctatatt aggcaaattg atatccaaga
    13621 gaattaagtc aggtgttgat tcttggatta cttgaagtac atcacaatta tttgtatcca
    13681 atgtttgtgt actatagcca ttattttcaa agaattgcat taattcctta cagatgaaca
    13741 catcatcttc aattatcaaa atattggtta aaataataaa tacctcattt ctttagttta
    13801 tattgcttta attttgtaag taatatattt ttccatatat tacttacaaa attacttttt
    13861 aattattcat cttttccagc tactgatagc tctttaataa caactgaagg tgaacctata
    13921 ctactcattg gaaattctaa atcttcccct ataacttcaa tatctttcaa caggtcaaaa
    13981 tagtttcctg ctactgtaat ttgctccact ggaaatactt tttttccttc tttgatataa
    14041 aagcctttgg cagctaaaga aaagtctcct gttactgaat ttgcacctga atgaagccct
    14101 gcaaagctag taaccatcaa tccttcatct atatccttta taatttcatc taaagattta
    14161 tctcctttat ctatataaaa attagttgga tatatgctta taggtgatga atatgaagat
    14221 tttattccat ttcctgtagt ctttacacct gccttattag ccgtttttaa gttatgaagt
    14281 aaagttataa gctttccatt taaaacaact tcttttttaa atgtagctac tccttcatca
    14341 tcaaaaggag tagatgccat accattttct aaaagtgggt catcaactat tgtaactata
    14401 ggagatgcta tcatgtctcc ttctctattt ttcaataaag ataatccttt ttgagctgaa
    14461 tctgcattaa atatcccaga aaatgtgcta agcaaagata ccatagcttc attaagcaat
    14521 atagttttat atttacctga tggaatactc ttaccaccta ctttagataa agcattatca
    14581 acaccaagtt ttgatatctc acaaggtttt atttcttcaa tagaatttgc tctattatat
    14641 cctattccat catatttttg tccattgtct tctatgatag gaactacaaa ccctataagc
    14701 atattagttt tattgcttaa attaagacct ttagtattag atataccatt acttgataca
    14761 gaataagata tagtacattt agataaattt accaccttat ctgaataagc tttagtctct
    14821 ctttccattt ctaaagctaa atcaatcaac ttatctgcct ctaaattttc tagctcttta
    14881 gaataagtct ttacatcatt atagtgctta tctccttcat atataaattg tacatcttca
    14941 ttttcaatag tgtttactcc atcttttaca ttttttatca acatatcaac agctttatca
    15001 tctaaaattt ctgtataaga ataacctatc tttccattta ccttacctct aaaagataaa
    15061 ccaaaagatt tatcaagatt gtatttctca acttctcctt catatatatt tatacttaaa
    15121 ttttctcctg tataataata tatttcacac tcttcaaaac cttcacttag agccttttta
    15181 aataatatat ctttaaaatt tttaagttcc acaattatcc ctcctatctt ccacctacag
    15241 taatttcttt tacccttatc ataggttggc ctacattagt tggtatactt cctgatgatg
    15301 agccacacat cccctgagct tgttttacgt tattcccaac catatctata ttcataagta
    15361 tatcgctacc ttttccaatt aaactagcac ctctcactgg ctcttgtatt tctccatttt
    15421 ttattaagta accttctgaa actgcaaaat taaactctcc tgttacagga tttacagaac
    15481 caccacccat ttttttagca taaagtccat ctggtattga ctttataatg tcttctggtc
    15541 tatcttctcc agcagcaata taagtgttag tcatccttga agttggtgca aatttgtagt
    15601 tctgtctacg agaacttcct gtaggattca ttcccattcg tctaccatta agtttatcta
    15661 tcatataaga cttcaaaatt ccattttcaa tcagtatatt cttttgagtt ggatttcctt
    15721 catcatctat attcatagaa ccccagtagt ttggtattgt accatcatct atagctgtaa
    15781 tctttgtgga agcaatctgt tgacctaatt tatctgcaaa tacagagttc ccctttgcaa
    15841 ctgatgtagc ttccaaagaa tgtccacaag cttcatgaaa tattactcca ccaaatccat
    15901 tatctattgc taccatcata ttacctgcag gacaattttt agcatgcaac atagtatgcg
    15961 ctactctagc tgattctttt gcataatatt ctgggtctat ttcttcaaat atttcaaacc
    16021 ctttacaacc tccaggacct tcaaatccag tttgattttc attaccctta gatgcaattg
    16081 aacttatccc tagtctggtt cttattcttc tatcctcaac atatatacct tcagtgtttg
    16141 caattaatat tttttggtct ttatccaaat agctaacact tacttgagat atatcattac
    16201 taaattcttt tgcactctta tatgcaacct tcataacact tactttatct ctatttccta
    16261 ttgaatttgg ataaattttt atattatgta tgttatttat tttaatactg tcatttaata
    16321 ttacactttt tccatcttcc aatttaccta aagcaacagc agctttgtat gctacatcca
    16381 acagactatt taatgaattg tcacttgtat aagcatatat actcttcaat cctttaaata
    16441 ttcttattcc tataccataa tttcttccac ctattgcatt ttctacttta ttatcaatta
    16501 aactaataga attatttata gtgtcttctt caaaaatctc agcaaaatct cctccagtaa
    16561 ttagacactt ttctaatacc ttagaagcta tattttttga aagcataaat ttacctccta
    16621 ctttaaattt ttaattaact tttattcaat ctttttactt gttaacaaac attatatact
    16681 atattactta aaataaggta attatgaata tattatacat atgttttata ctaaaatgtt
    16741 atcacatttt atctatacat acccatataa ctagataatt aaaatgtata atattatttg
    16801 ctatagaaaa taatacactc atacataata aattttagga gtgaagtata tgaatcaaga
    16861 atatgtaaaa ggaaatccta tttttactaa tattaataaa gttccaagac aatttccata
    16921 ccttactgat gatattgata ctgatgttat aattgttggt ggtggcgtaa ctggatgtat
    16981 ttgtgcttac tatctagcta aaaacaatat aaagtctgtc attcttgaaa aaggaaggat
    17041 tgcacatgga agcactagcg tgacaacttc tctattacag tatgaattag atgacaattt
    17101 gatagattta acagaggtta tgactctaaa agatgctcta aaagcatata acctttgtac
    17161 ttcagcactt gaagaattag atacatttat aaagctatat ggaaataagt gtgattatgc
    17221 caaaagagat actctacttt atactgccaa caaacttgaa attaaggcta tcaaagaaga
    17281 atataactta agaaaagaaa atggatttga tgttgaatat attgatgaat ccacaaaccc
    17341 ttttagcttt gatttaaaat caggattgat agcaaagaat ggaggacgag aattagaccc
    17401 atataaatat agtcaccatt tgattgatgt aagtttaaaa aatggtcttc aagtatatga
    17461 aaatacagaa gtaaaaaaag tagatttatc aaatgataag gttactgctg aagtatcgta
    17521 tggatacaaa gttcatggta aaaaattaat tgtagctaca gggtacaata caagtttatt
    17581 tacaaaaaga aattttgcaa ctaagtcaaa tacttttaat atagcaacta aaccacttaa
    17641 aaacatagct tcttggaaaa acaacatttt aattagagat aactgtgacc catataatta
    17701 tctaagaact actaaagaca atcgattaat tataggtggt gaagatgtaa gttttgatga
    17761 tatagaaaat gaaactttag ccaatgaaaa gtatgatatt ttagaacaaa gattgaaaag
    17821 tatgtttaag gatataaaag acattgaagt tgaatataaa tattgtggtt gttttgcttc
    17881 aactttagat aatttaggtt ttattggtcc agataataaa aataacaatc tatggtattg
    17941 cttaggttat ggagcaaatg gtatactctt tgcaatatta ggaggtataa tgttaagtga
    18001 attatatctt ggcaaacaaa ataaaaatat gaaattattt aaagtagata gatttgataa
    18061 atagatattg tatattaaaa gactataaaa agatgaaact ttataattct aaaagttaac
    18121 tttgatacag tcttttataa tgttcctttt aaaaatactt tatttataat taaatataaa
    18181 gtaaaatgtt aaaatataac tgataaaatt tagtcataag ataatattta agtttatttg
    18241 atgaaatatg gaggaattat tatgaaagaa atactcgtta ttgctcccac taaaggaacc
    18301 tatgaaaaat caattcacat agttaaaaaa aacaaatata caaatattga tgttgtattt
    18361 ggcaatctaa aagaaggtat acctcttgct gaaaaaagta ttaatcatgg tactagaatt
    18421 atcataagca gaggtggaac ttacaatatg ttaaaagcta cttacaatat acctatagtt
    18481 gaaattaaag tagatgctta tgatattata aaaagttaca aagaggtaaa aaattccaac
    18541 gaaccatttg gaataattgg atttaataat gtcatctacg gtttcgatat tatagaagaa
    18601 atattgaata agaaaataac tatgattgaa attgaaaaag aagaagaaat ttatgatgct
    18661 atagaaaagt acagaaagaa aggtataaac acatatatag gagataccac tgttgcacat
    18721 attgttaaga gacttaattg taagggaata ttaatcgaat ctagagaaga aaacatactt
    18781 agagccattc aacaagcaga acaaatactc gaagcaacca aggatgaaca aaaaagaaga
    18841 ttacagatag aagctatgac agattttgta catgatggaa taataacagt tgataaaaat
    18901 tttaaaataa cattatttaa taagagtgct gaaaaaatat ttggtataaa aaaagaaaat
    18961 gcactttatc ataatgttgt agatgttatc ccaaacacag ttcttccaca agtagttgag
    19021 actatggaac ctcaaattgg tgaaatacaa aatataggga gtacaaaaat tattacaaat
    19081 agagttccaa taattgttga tggccagatt caaggggctg tttcaacatt tcaagatagc
    19141 aaggagataa gttcttttga acatacaata agaaggagct tattaagcaa aggtctatct
    19201 gctaaataca cttttgataa tataattcat gctagtgaaa agacaaaaga ttgtatagaa
    19261 cttgcaaaaa aatatgcttg ttatgatact cctatgatta ttactggaga atctggagtt
    19321 ggtaaagaat tattttgtca aagtatacat aactatagta agcgtaaaaa tgcacctttt
    19381 gttgctgtaa attgtgctgc catacctcca tctctaatag agagtgagtt ttttggttat
    19441 gaggaaggtt catttacagg tgctagaaaa aaaggtaaag caggtgtatt cgaactagca
    19501 catgaaggta caatcttcct agacgaaata agtgaaatcc ctcttgaact tcaaggtcga
    19561 ttattgaggg tattgcagga aaaacaagtt atgagaattg gtggtgataa agttattcct
    19621 atagatgtaa aaattatctg tgcttcaaat aaagacttaa aaaatatgat gcgcaatggt
    19681 ttatttagac aagaccttta ttttagaata aatatactaa cattatatct tccttcatta
    19741 aaagaaagaa aagaagatat tataaaatta tcagaatttt ttatacataa atattcaagc
    19801 aaatacaata aaacgccttt aattatcact ccaaatatta aaaaggcact tcttgaacga
    19861 gaatatgaag gtaatataag ggaattggaa ggtatgatgg aaagggctgt tattgtggaa
    19921 tcatttgact cgattttatt agaaaaggtt agcaatgaat atacaaataa tatagttgat
    19981 aaagataata gtgattttga atgcagtaat ttagatttaa aaactttaga aaaaaaatat
    20041 atctataaaa tttataacga aaataataga aatactacaa aaacctgtga aattctaaag
    20101 ataactcgct ccactctatg gcgtaagtta aaagaaatag aagatgatgt ttaaaaataa
    20161 tacataccta tatatatcaa aacgttttat gtttaatttt aatacataag gcgtttattt
    20221 gttttcaata aaaaatacaa ttatatgata aaaagaatct ttgtaagtga aattctcatc
    20281 aatcatacct ttaattataa gtaatctaca gcatttcaat cgattattaa aaataatcat
    20341 gataactaaa aatacaaact ctatatattg gcatagtaat tgcttttata atacctatat
    20401 aaaaatgaaa gggagtgata ctagatgcac atcttaaaat cagtgaaaaa gataccagga
    20461 ggacttatgg tctgtccctt gttattggga gcactattta atacagtatg tccacaagct
    20521 cttgaaattg gaggattcac aacatcctta tttaaaactg gtgcaatgag tatacttgct
    20581 ctattttgtc tatgcaatgg agctcaaatc aatatcaggc aagctggtaa gccattgact
    20641 aaaggtatag tacttacagc aacaaaattt ataattggtg cagtattagg tattattgtt
    20701 agtaaattta ttggacctaa aggtataatt ggtattacac ctcttgccat agttgctacc
    20761 atgactaatt caaatggagg tctatttgct gctcttgcag gtgaatatgg tgactccaca
    20821 gatgttggag caatatctat cttatctcta aatgatggtc ctttttttac aatgcttgct
    20881 tttggagtaa ctggacttgc aaatgtacct atagtagcac tatttgcagc acttatacca
    20941 atactacttg gatttatact tggtaacctt gatgaagata tacgagaatt tcttgcacct
    21001 ggtacaacat tattaattcc tttcttcgct tttcctttag gagcagcatt aaactttaat
    21061 caaattataa ctgctggact acctggagtt gtacttggtt taggagttac tataataaca
    21121 ggtatgggtg gctactttgt aatgaaactt atacgtgcag aacatccagc agtaggtgca
    21181 gctacaggta caacagccgg aaatgcagct ggtactcctg aagctttagc agctatagac
    21241 cctactctag ctacaatagc agctgtttca acagtacagg ttgctgctgc tattattgtt
    21301 acagcaatat gttgtccaat gttagtttcc tatctagata aaagagaaaa aaagaaaaaa
    21361 tctattttta aaacaaataa aaatattgaa gtaaattaat acttaaggag gtaaaattaa
    21421 tgaatgcaat tattcatgca aatgaaaaag ataatctagt tacatgtgtc agacctttag
    21481 ttaaaggtga aaaagtttca attgatggaa agtcttacat agtaaatgat aatatacctg
    21541 tctttcataa gatggctaca gaagatgtaa aaaaaggtga tgttgtatac aaatacggtg
    21601 aaattatagg aattgcaaca gttgacataa aaactggtga ctatgttcat gtacataaca
    21661 ttgaaagtac acgtggtcgt ggagataaaa aataggagga agttaaaatg aaattaatgg
    21721 gttatttaag agaaaatggt cagtttggta ttcgtaatca tgttttaatt attccaacat
    21781 ctgtatgttc aagtgagaca gctacaagaa tagcatcact tgtgcctgga gcaatagcaa
    21841 tccctcatca acatggatgt tgtcaaattg gttctgatat agagcttaca gcaaagacat
    21901 taataggatt tggaaaaaat cctaatgttg ccgcagtttt agtagttggt cttggatgtg
    21961 atggtattca agcaaaagaa ttagcatctg aaatagctac aacaggaaaa aaggtagatt
    22021 acgttgttat acaagaatgt ggtggaacat taaaaacagt ttctaaggga actgaaatag
    22081 taagtaaaat ggctcgtgaa gtatcaaaag aagtaagagt tgaatttggt atgagtgaaa
    22141 ttacattagc acttgaatgt ggtggttctg acccaacaag tggaatagct tcaaaccctt
    22201 caataggcgt tgcatcaaac cttcttgtag atgaaggtgg aagtagcata ctaagtgaga
    22261 ctacagaagt aattggtgca gaacatttgt tggctacccg ttttgaagat gaagaaatga
    22321 aagataagtt tcttaaattt gtaagtgatg tagaaaaaag agcaattgct atgggagaag
    22381 atttacgtag tggtcaacct actccaggta ataaagctgg tggactttca acaattgaag
    22441 aaaaatcact tgggtgtatg tataaggcag gcaataagcc attcaaaggt gctcttgaat
    22501 atgctgatat tgtacctcct gataaaaaag gattatattt tatggatact ccaggtcaag
    22561 atatagattc tatcactggt atggtagcag gtggtgcaca aattgtaatc ttttcaactg
    22621 gtagaggtac tccaacagga agccctattt caccagttat taaaatcact gggaatagtg
    22681 atacatacaa caaaatgcca gacaatatcg atataaatgc aggtagaatt ataacagatg
    22741 gtgctaaaat agcagatata ggtcaagaaa tatttaatga aataatagaa gtctgtaatg
    22801 gtaaacatac caaagctgaa agtcttggtc atagagaatt tggcatttac agaatttcat
    22861 ctacatttta gattgtaaca aaatatcttt tataaatata atacttatgt agatacataa
    22921 gctaaaagtt ctttctaatc ctataaaaat tttctatact gaaaaggaac tgtatcaaaa
    22981 ttattttgaa aacagttcct tttttaacct cttttactca aaatattata aaataagatt
    23041 taaacaataa acgtgtcttg attaatctct aagaagacat aaataaagct aaatgtaaag
    23101 tgagataaat aaaatttaat atctttgtat gaaaagatat ttggtataat atgtctgaga
    23161 gaattcttat ttgtaaacaa ataaaggatg gaggatgaaa caaaagaatg aactttgaaa
    23221 acacaaaaaa taaaaaaata atagctactt tactattgac actcctttta atcgtgtcat
    23281 taacatgtgt caattttatt atgaatctaa ataaagtaac acataatgaa acagaacgat
    23341 atcttgtaga agtttcacaa agtatttcca ctacaattaa tgtgaaatgt aaaagtatat
    23401 ttaggacact atattctatg ggagatactt attttgagat taatgatagt gaaaaagaag
    23461 tcaatagata cttatcaaaa aaattaaaat tatttgaatt tgattggtta ggtattatag
    23521 attctaatgg aaattttgta agtgccctta aagatacagg taatgttaaa ggacaagact
    23581 tttatagaaa agcccttcaa ggtaaagaaa caattactcc tgttaaatca caatctggta
    23641 catatggaat tttatattct gtaccactat acaatggcga taaaattgtt ggagctgttg
    23701 ctgcttggaa tactattgat actatgagaa atttattaag tgtagaaagc tttcatggtg
    23761 aaggattttc ccaaattatc gaccaagatg gaaattttat tgtaagttca gcaaacaaaa
    23821 atgctccaaa aaatgtggta aatttttttg acatgattaa acaccaagga aaacaggttg
    23881 ataaaaataa acttgaagaa atgaaaataa acttaaaaaa gaacaaaact ggttctatgt
    23941 attatacatt aaatgatggt atttctaagg caatgcatta tcttccatta caagaagaaa
    24001 acttatacct cctttcagtt gttccaacaa aaacagcaag tgcacagttt gatttacttc
    24061 taaaaaaagc aatcttcatc aatattttaa ttgttatact atttttattg cttattatat
    24121 tgattatgtt tataaatcaa aagaacaggg cacaacttat aaaaatcgcc tatgtagact
    24181 ctgtaactaa aggttacagt aaagcacgtt ttgatattga agctaaaaaa attatacagt
    24241 catcttcatc agaaagctat tcattggtat ctataaatat tcagaaattc aaacttatta
    24301 atgattcttt tggtagtgaa gcaggagata aaacattaaa gtacatacat gatgtcatta
    24361 gtaattatct agaaccagga gaattgcttt gtcgagtttc taatgaccag tttaatgtac
    24421 ttattaaaac tattcctcaa aaagaaattc ttaagtacat agaaaatatc accaatgata
    24481 ttaatagttt caataaaaat gaagaatgta aatattttat agctctatct ataggtgtat
    24541 ataaaattga tgacccaaat ctacctttag tttcaattca agaccgtgca aatgttgcac
    24601 gaaaaaataa taaaggaaac attggaaatc atccacttta tacatgtgtt ttttatagtg
    24661 atttagagcg tttaaaaatg attaaagaaa aagaaatgga aaatagaatg gaggaagcat
    24721 taaataataa cgaatttata gtatatcttc agcctaaaat aagcctcaaa gataatacta
    24781 ttgtaggtgc agaagcatta gtaagatggc aagacccaaa taaaggcctt ataccaccag
    24841 acgagtttat tcctttcttt gaaaaaaatg gttttattac aaaactcgac cactatgttt
    24901 ttgaaaaagt atgtagtatg ataagaaaat ggatagataa tggagaaact ccaatgcctg
    24961 tttcagttaa tttttcacgt gctaatttaa ataatataga ttttttagaa aaatacagaa
    25021 tgcttcgtaa taaatacaac attcctgcta agctcttaga aattgaatta actgaaacac
    25081 ttgtatttga aaatctccaa aaattaatta atataataga ccaaatccat gaagaaggtt
    25141 ttcaatgttc actagatgac tttggaagtg gatactcttc actcaatatg ttaaaagaaa
    25201 taaaagttga cacatataaa acttgaccgt gcttttttta gctcacctaa tgcagataat
    25261 attgctgaaa atcatgtaat agaatctata gttaatttgg caaaaaaatt aaatatgaat
    25321 agtatatcag aaggtgttga aacaatcttg caaatggatt atcttaaaaa aattaattgt
    25381 gatatgatac aaggatatgt tttttcaaaa cctctgcctc aagaaatatt tgagaaaatg
    25441 acttttggaa aaaaactaga agaaaccagt atggatagtt ccgtttaaat aaaataaaaa
    25501 acttgtctct ataaaataat tttaatcatt ttataaagac aagtcttttt attttccaat
    25561 ttaattttat tttctaaatt tcttatactc ggcttgtttt aaattccctt tttaagaata
    25621 ataatacgat tatcatagca ataaaatctg caactggctg tgccaaccaa acaccatcta
    25681 aattaaattg aattggaagt acaatgatta atggtataaa taaaataaat tgtcttaaaa
    25741 gagttaaaaa cattgaatgt ttaactttac ttatacactg aaaatacaca ggtcctacaa
    25801 tagaaatccc cattataggc aatgtaatta gatttatgct tatacctctt actgctatat
    25861 ccatcaaatc tgaatcttta ttaaatatac ctacaaatac ttctgggaaa acttgtacta
    25921 ttaaaaatcc aaatgacaat atgacaactg acactatgat agataatatt aaagttttct
    25981 ttgcacgttc atattgtttt gcaccataat tgtatgatat tatagtttgc ataccttgat
    26041 tcaatccaaa cacaggcatc ataaacatca ataaaataga tgtaagtgct gtcatagccc
    26101 caatagctaa atctccacca taaaccttta gagaattgtt tgtaaacatg tgagttatac
    26161 ttatagctac ttccatagca aaaggtgtca ttcctattgc aaataccttc tttactatat
    26221 ctttattcaa ttttaagtta cattttttta gttttaaagt ggacttccct cttataaaat
    26281 aatatgttac ccaaaagaat actactattt gacatagtac tgttgctata gctgctcctt
    26341 ttatacctaa attaaacaca aatataaata tagggtccaa tatcaggttt aatacacatc
    26401 ctacaatcat tgtccttgct gctaattttg gattaccttc tgctctaatt gcattattaa
    26461 gagaaaatgc aactaaatta aatatacttc caatcaatat gacactcata tagtcttttg
    26521 cataaaatat tgaatcttta cttgcaccca aaataaaaag tatatcttct aagaaaacta
    26581 atcctaatat agttataatt aaagagataa ttatagataa tgtcaaagca ttacctaata
    26641 tcttctctgc ttcttctcta tttctttccc ctaattttat agacaatctt gtgctagcac
    26701 ctactgatac caacattcca aaagctatta ttagagtaaa tactggcata gttacaccaa
    26761 gacctgcaat agctatagag ccaatacctt ccatagaacc aataaaagct ctatctacta
    26821 cattataaag tgaagttacc atcattgcta ttattgccgg tatcgaatac ctaaataata
    26881 aaatccatat tttttcatgt cttaatgctt cttgattctc catgttgtca ccatttacac
    26941 catgtcataa gttatacaaa ttggtttatt tgttcttggg tctgttgcta tttctgcatc
    27001 aatattaaat aattctttta gattatcctt cgtcataaca tcatatgcat caccttcaca
    27061 aactatttta cctttcttaa tacctatcat gtggtcagca aatcttgctg cattattaag
    27121 ttcatgtatt accatgacaa tagttcttcc ttgtttttta tttagttcat ctaataattt
    27181 tagtatctct aattgatgtg ccaaatctaa atatgttgta ggctcatcca gtaataatat
    27241 atcagtttct tgtgccaaag ccatagctat ccatgccctt tgtctttgtc ctcctgataa
    27301 atcttccata tttctatcct taaattctgc aattccagta acttctaaac tccaatttac
    27361 aatctctctg tcttctttac tagaattacc aaatccactt ttatgaggaa atcttccata
    27421 agaaattaat tctgaaacgg taagaccact aggagcttga gggctttgtg gaagtacagc
    27481 catatccttt gctatttctt tagacttctt tttgtagatg tcctctccat ttatatatat
    27541 tttcccacta ttagggctaa taattctacc tatagtttta agtattgtcg attttccaca
    27601 accattagcc cctatgatgg tagttatttt tccttttggt atatttaaat ttaaattttt
    27661 tataatatct gtgtttccat atgatacatt tagattctta gtatttatac agttcataac
    27721 aacacccttt cctaatcatt taccaacatt aaataaataa agtacggcac tcctattata
    27781 gaaactacta tacctactgg tatttctata ggtgctagaa gatttcttga tatagtatct
    27841 gctattaaaa gtaataatgt tcctatcaat gctgatactg gtattaatct tttatgcttt
    27901 ggtcctatta tttttctacc tatatgtgga gctattaaac ctaaaaatga aatactacct
    27961 gctactgctg tcgatacacc agataaaatt actgcatata ttataagtct tcttctttgt
    28021 ttttctacat ctacaccaag acttatagat acttcatcac ccaaatttaa aacatctata
    28081 tatttagatt tataaatagt tatacccata aaaatcacta taaatggaag cacagctatt
    28141 acatatttcc aactggttcc ccaaatgctt cctgatgtcc atgccataac cctattaaat
    28201 tcttgtgttg taaatttcaa ttggaatatc gtcaaaattg aagtaaaagc tatgtttaca
    28261 cctataccaa taagtagtaa tcttgacgaa tttataccac ctttccatgc aagagaatat
    28321 ataagaaatg ctccaaataa agctcctata agtgcaacaa taggcattgt aaatacagtc
    28381 aagttactca taccttcata tacattacca ttcataaggt atatataaac tactacaaac
    28441 aatgcagcac ctgaatttat tcccaaaatt ccagaatcag ctaaatcatt ctttgtaact
    28501 ccttgaagta ttacacctgc tgttgataat gcagaaccaa ccaaaagtgc tattactatt
    28561 cttggtaatc ttaatttaaa tattgcaatt tcatgattac gctgaccctg ccctaaaaaa
    28621 gtctttataa catccattgg ttctatagaa aatgagccca tatttaaact caataaaaaa
    28681 gtgataaaaa taagcaccat taaaattgat ataacaagta atgttttaga atttattttt
    28741 ataatatttt tcatagtacc tatttctccc cctttctaac aaggtatata aatattggca
    28801 ctcctataag tgctgttata gaacctactg gtgtctcata tggaggattt atcatcctac
    28861 ttaatatatc tgtatataca agcaatacag ctcctaatac taaagagctc ggtattatat
    28921 acttataatc tgaacctact attcctttag ctatttgagg aactataaga cctataaaaa
    28981 taatattacc agacactgac acagatgctc cagtcattaa tattacaagt actatacata
    29041 taaatctaac aaagttagtt ttttgtccta atcctattgc cacttcttct ccaagactta
    29101 atatagttat tcttggagcc ataataatag ctaaaataaa tccaatacca ccagctacaa
    29161 atagcaattt tataccttcc cacttcactc ctacaagccc tcctgatatc cagaaactta
    29221 attgttgaga taggttaaaa tacatagata ttgctgatgc caaagaaatt agcaatgtac
    29281 caagagcgac tcctgcaaga gctaatttta cattattaac tcttcctctt gatttagaac
    29341 ttataaaata tataaataat ccacttatac ttgctccaat aaatgcaaac atcattacac
    29401 taaaacttcc atgtataagt tgaggaagtt ttttttgaag taccagtgat atcgaaattg
    29461 cgaatgtagc tccttgtgta attcctataa cagatggttc agctatagga tttctcgtta
    29521 ttccttgcat tattgcccca gaaactgcta aaaaccctcc aacaagtgca gctgctattg
    29581 ctcttggaag tctaacatcc tttactattc tcatatttat tccatcttcc atttttatca
    29641 aactatctat gacagttgat agattcatat cttttgcccc aatagttatg gataatacaa
    29701 ttccaaatac aagtacaact atacttacta atatcaacaa ataagttata ttttttttac
    29761 tcagcttagt caattatcct acctcctttt cccttttaat cgtcagtata atatcatcta
    29821 ttaagtattt taattttaag atttattaaa aataggtgtg aaaaatgaat atcattatct
    29881 cacacctact aagttaagaa ttactttgtt aattcatttt taactgattc taataataac
    29941 tcttttccaa ttggattgta tgattgactg aaaaatggag cagcatcaag tattgttaca
    30001 ttaccatctt ttactgctct tatttgagac cagatagcac tattttctaa atctttttta
    30061 tctgcttctg tagcaattac aactatatgg tctgcatcta tatctgttaa accttccata
    30121 cttaccattg gtagtgttat tccatcctgt tttggcatat tcttaggtct agctaatttc
    30181 atatcatcat tgattagagt acctattcca ccatcactaa ataccataaa ttgacctgaa
    30241 cttgccaaca ctggtaaata agttttttct ccattctttt ctataacttc cttacctaac
    30301 tttgtagctt tttcatcata cttctgtagc caacttttag cttcttcttc tttgtcaaat
    30361 aactttgaaa catcagttaa cttgcttctc cagtcatttg cataatcttt catcataact
    30421 acaggagcta tttcttttaa ttggtcatat attttttctt gtctttgact cattattatt
    30481 aaatcaggat ttacttctaa tatagcttcc atatccatag tatccatcat tgagtgccca
    30541 actatcttta cacctttaag ctcttctctt atgtaacttg gtaatttatc agtttcatat
    30601 gagtctacat ttgctgttgc aacaggctta taacctgcta ataatagttc ttcactactt
    30661 cctgatatat caactatttt tttaggattt gatggtatct taacctctcc tttaacagat
    30721 tgtacaactc ttgtctctga tttatcttta tcctctgtat tcttatctga acatgctgta
    30781 acaagtacta acgtagttat aatagatata aatattgcaa gtgattttat ttttttcatg
    30841 attacttctc ctacttgttt attatactta catgatattg attatcataa gcacatattt
    30901 attatagcat ttttctattt ttagtcaata ttattttgta aaaggataaa aattcctaat
    30961 taatcttaat tatatatagc ttagataagg ttttcttata ttaaacagta ttttttttaa
    31021 gaattggaca caaacacaat gacttttagg ttaaacaatg ataaaatgca atttatagat
    31081 aatgaattta gtaaggagga ttcaaaacat ggtacattta gtatattgtg ataatgcagg
    31141 aaaaaaagga gaaaaggtct tagataaaat cttggctgga acaaaaacaa tggttattag
    31201 aggtgctgct ggtagaaaaa taccacatag tagagtattt gaagatgagt tactttattt
    31261 tatggaaaaa ggaactggaa aaatatctgc aaaagccact gttaaaaaag tagaaaacta
    31321 tgttaaatta acagaagatg aaatttctaa aattttaaat gaaaatcaac caaaattaaa
    31381 tttatctgaa aagcaaaaag ttcgttggca taaaaaatgt ttatgcttag ttgaatttga
    31441 aaatgttgaa gaaataacac ctcttgattt tgaccatcaa ggaaatatgg atgattggct
    31501 tattgttgaa aaaattgaag atgtagttgt tggtactagt ataccttaca attatgagaa
    31561 gtctaaattt taaagtatca ataacataat actatattgc taaactctac ttaaataaaa
    31621 aaagagtgca tttaataatt ataaaaatta tttttataca ctctttttta ataataaatt
    31681 taaattactt actttctaat ctttcatata catctataaa ttcttctgct aattgttgaa
    31741 aattcatagc tgtcattaaa tggtcttgtg catgaataag tataacactt atttcagttt
    31801 tattaccatt agcttcattt tgtatcaatt ctgtttggaa tttatgagct ttatgaattg
    31861 attctttcga cttttcaata cattctctag ctttatctat attcccgctc tttgcttctt
    31921 ttattgcttc aaatgctagc cctttcgcat cacctgcaaa tccaattatt ccaaaagata
    31981 tctctatcat cttctcatcc atttattcga cctcctaaat atctctatag cttgatatga
    32041 ctaatccatt cttttctaaa aattctttga cttttttaga tgtaagtatc ttgtgctctt
    32101 tcgttctatc aatagcataa gatgtagaat ttaaaatata atcatctaaa aaagctgggt
    32161 gagacataat atccactaca tcatacttca ttatttcgtc tatatttttt ataaaatatt
    32221 cttcacttac attttcctta taaaaactat ctattaaagg aactacttta gaatactcta
    32281 aattatattc aaatccacct cttattggaa gattatactt ggttacaatc ttctctacta
    32341 ctggctttaa acttactaaa gtatggatat gatggtgact atctaaatga gatatatcta
    32401 ttccaagccc ttttacccta tctatttgag cacaaagttc tctataaatc tcatcacaat
    32461 ccattttttc aataatttcg tctgtaatcc tcctaataaa aaaaccgtct ttatcaacaa
    32521 tagtttttaa gttagataat aatggtctac cacaacttaa agtcatatga actccacaat
    32581 ttaaagtttt attttcttta agtaagccta ctccatgttc taccccaggc atatttgcca
    32641 tcatagaagt agacctaact ataccattat tatgagctga aattattcca tagttcacag
    32701 cttcacaata tccaaaatca tctgcattta ttataatttt agtcatacca taacctactt
    32761 tctatagaca actatctatt aaatctagga agataatctt tatgagcttc caacatttcg
    32821 tctaatatag tttttgctaa gtcatcagat ggaatcaatg ggtttataca aagtgccaaa
    32881 agagcagatt cataatcgcc atatacagct gctttagcta ccaatacttc aaatgatttg
    32941 atttggctta ctaatccatg cacagaatct ggtaaatatc ctatacttat tggttttgga
    33001 ccatttttgg ttattacact actcacttct accgcttgtt catctttaaa atctcttata
    33061 gaaccattgt ttaatgtatt aactacttgg atatcttttt tgtcattgta tatagaactt
    33121 attaaattac aagcagcatc actatagtaa gcccctcctc ttttttcaag ttgaggtggt
    33181 tttacatcta atttttcatc cttatataat tcaaataatt gttcttccaa ttctttaact
    33241 acttgacctc tagcttttcc ctctttaaac tctctcaact catcctcaag catttcttta
    33301 gttttatagt agtatctatg atatggacaa ggtattgcac ccaaagattt tacaaattca
    33361 gcattaaaat caattgcctt tatattttgc atacttatat ctgctttgac aaacttatca
    33421 attgcttctt ttgtaacatc ttctccatct aaagatacat ttagaccata aaccatatga
    33481 ttaagacctg caaaatccat acttattctg tcactttcta cattaaatag tttggcaaca
    33541 tcatttttta aatgaattgg cacattgcat agacctatat atcttctaaa attagtatat
    33601 ttgaatacag cctctgttat tattcctgtt ggatttgtaa aattcaccat ccatgcattt
    33661 ggacataatt cttccacatc ttttattata tcaaatataa ctggtattgt gcgaagggct
    33721 ttaaataaac ctccagcacc attagtttcc tgccccataa ctccatgaga taaaggaata
    33781 gtttcatctt ttattctcgc atctaaaaga cctactctaa gttgtgttgt cacaaagtct
    33841 gcatctctta gagcttctct tctatctaaa gtaagattta ttttcatatc tactccagct
    33901 ttttttacca tcctcttagc tagatttcca actatctcta atttttcttt tccagcttct
    33961 atatctacaa gccataattc ctttacaggt aactcttcat atctatttat aaaaccctct
    34021 acaagctcag gagtataact tgaacctcct ccaattgtaa ctatttttag tccctttttc
    34081 atctcattat accatcctta cctataattt aatatactct acaaaaccct atacatttat
    34141 ttaccgaaat aaaactacct agttgttaat tttcaattta ttagcttcca ttttttcaga
    34201 cgctatgaca aatggaatat atattaatat tgataatatt aaattaaata gtgctaaagc
    34261 tccaccagtc cagtcacctg tagccatcgc tccacctaat ataggaggtg ttacccaagg
    34321 tattttaggt aaaattactg gtgctactaa tccaaaatct attgctaagt atgatacagc
    34381 actacatatc actggtgcaa gtacaaatgg aatcataaat ataggattta aaactattgg
    34441 aagtccgaat atcaatggtt ctcctatatt aaatattgca ggtggcccac ctaatactat
    34501 catttcttta cgtcttctcc cagctattaa taaagctact attaatccca ataccattcc
    34561 agaaccacct aaatatacaa atgcatcaaa gaatgcacct gcaagtacat ggtatccttc
    34621 cgttgctcct gcttgagcca aggcagcatt ttctccacct aatttcataa gtatagtttc
    34681 tgtaaaagga agtgctatat ttgcaccatg aagtccaaca gtccaaagta tatgaattat
    34741 aaatgcaata agcattgtag aacctagact atcagctaca tttgatagcg gtgctcctaa
    34801 ataagtattt aaaatatctg ttaagaaact tccattagaa agcattttta taaatattcc
    34861 tattacagta aatatcatta tagttaacat tcctggtatt aactttgcaa atgatcttga
    34921 aactgctggt ggaactccat ctggcatttt tatagttaat ttctttacct tagataatct
    34981 tacaaatatc tcagttgata ataatcctat taatatagaa gagaataaag ctgctgtacc
    35041 taagtaggtt tgttgtatca ttccccatcc ttcaactact gtagttcctc cctcaggaac
    35101 tattttacca atttgtggag ccattataaa aaagatagat aaagctataa gcccagattg
    35161 taacccatca ctctcataag attttgctag aaaataagca acacctatta ctaagaatac
    35221 tgccattgta cctattgctc cccaccaaag gtcgcctcca aatgtggtcc aattttctcc
    35281 aaatatactt gccatcaaat ttttgtatgc ttccaatggt aagttattta tcaatgttcc
    35341 caaggcacct accatagtta taggtatcat tactataaat gcatctctta ctgctactaa
    35401 gtgcctttga gctcctattt tagcagctac aggcactata tatttatcca taaatgacat
    35461 gaatttttcc attttacatc ctccagtaca actttatttt gaactattta actctacagc
    35521 tctatctaac acagcttttc cattacatct tccataatcc atcatattta taacttctac
    35581 tggaatatta tatggttttg ccatttcagt tgcttttcct aatacatatc taacttgagg
    35641 ccctaaaagt aagacatcac aattttctat ttcatttttt aagttcactt ctgatatagc
    35701 ccatattttt gcttctatac cgttttcctt tgctgcatcc tccatttttg taactaataa
    35761 actagttgac attcctgctg aacaagctaa cattattttt atcatttttt cccctccaaa
    35821 ttagattcat taaatatttt ttaagtcata aattttttaa actatacatt taaaatatgc
    35881 ttttctatta attttttctt aatgtatata tcttattttt aaatgtatat acatttaatt
    35941 cttgatatta ttatatacca aatgtatata catttcaaga aaactttttc attttattta
    36001 aattttattc gacaacagca ttcaaagtta atgtatatcc atagtgatat gtgtgtgagt
    36061 actcaaaaat ctcactattt tgtaacttac aaatttggct tatatataaa agtggctctg
    36121 gttcttctaa ttttagatta tccatacatt cttcattcga tattacagct tgtacttctc
    36181 tctctgacat ggctatcttg tatccacaca cttcttcaac aaaattataa agagaatttt
    36241 cacaatgagt cttatttaaa tttggaaata acttaactgg catataagta atcatatatg
    36301 aaactcttgc atcattggct aatcttactc tttttatttc ccaaacattt tcttctaaac
    36361 ttatattcaa cttacttgat aaattttcat ctgcctgaac tatttcaaga gataccaata
    36421 tattagatac tttatagcct ttactttcca tctctttagt aaatccactt acagacgata
    36481 tattatcata tatattattt gcaataacta tactacctac acctctttgt ctagttatat
    36541 agccttcttt aactagatta ttaagtgcag accttacagt cattctagtt acattaaatt
    36601 cttcactcag ctgtttttca gaagggatta aatccccttc tttcaaactg tctgaattta
    36661 ttaactctct aacatgattt tctataactt tataaattgg ctctttcatt taattcactc
    36721 cttattaatt aaatctttta tataataaga taattttata tacaaataaa gaaaatgtct
    36781 atacatttaa gataatttaa attttattca gacatcttgt acaactttcc gagttttaat
    36841 aaagatataa atagacttat cattaatata ccttttaata tacttgataa ggttatactc
    36901 caccatacac catttagacc caacatttct ggtctagata taaagtaagc caatggtact
    36961 cttgcaccag tcagtatagt aattataata gaaggtatat aggttctgcc taatcctttg
    37021 aaagctcctg ttgttattat ttctaaacac ataaaaaatt gagaatagcc taatatttta
    37081 agataaattg ctcctttttc tattgcctca ctttcatcta taaaaataga aaatatactc
    37141 tctcctgcaa atactaatac caaagtagtt attatcccaa gtacagaaga tacagttata
    37201 gctattttgc aacctttatt tattctagaa tacttcttgg caccataatt ttgtccaaca
    37261 aaactgccta atgcaactga tagcccttca gccgtcatcc aggaaattgc ttctatttgt
    37321 gagcctactt tttgtactgc aacagccaca ggcccccatg atgctactat tactcctaat
    37381 agcattgaga atactgtaaa cataccactt tgtattgcta taggtaatcc caatttatac
    37441 agaactttat aatatttagt ctctatttct ttaaatagtc ttaatttaaa atattcttct
    37501 ttacttttaa ctattatata tataaaacat gtagtaacta ctatctgagc aaatacagtt
    37561 gcaatagcag ctcctgcaac accaagtttt ggagcaaatc cccatccaaa aattaatata
    37621 ggatcaagta taatattagt tattaatcct actgtattaa tacgaaaagg agttttacta
    37681 tttccaagac cgttgaaaat tgcagtaaat actggattaa taaaataaaa taccatacct
    37741 agagctacta ttatcaaata ctgtctagac atggttataa cttctaagtc tcctaatcta
    37801 aaaaaaccta tcaattgttt attaagtact attaaagaaa ttgtatatat tattgctagt
    37861 ataatattta tttctattgc tgacttcata tatgatttag tagtgcttat attatttgca
    37921 ccaatacttt gtgctacttt tatctctcca cctacttttg aaatcataat aaatgccatt
    37981 gcaagccatg gaaaaaaacc agctgttcca actgcagcta ctgctttact tccggcttta
    38041 ccaacccata tcatatctat catgttatac cccatctgta taaatgaagt ccccattatt
    38101 ggaagtgata gcttaagtaa tttttctgta attcttcctt ctgttaaatt aattctgtct
    38161 ttcattttcc acctctttta tattaaattt atttgcttat atagctagat taatcatttt
    38221 atttgattga gttcactatc cttcaattta tattatcata tctcaagatt gcatctcaac
    38281 catacttatg tttaagataa agtattttac ctatctctga taaaattaat acttatgaat
    38341 ataaatatag tcatttcatc aatacatatt ataaccctta acttaacttc aattaagtat
    38401 acatactgta atcaattaga atattttata atgtatcttc cattaagaaa taacaaatat
    38461 aagtgattta tctataattt tatttataca taaaatagta tactgcaata ataaaaaaac
    38521 tatatttgaa tactttaagc atgtttacta attgtaattt ccacacaaat ttgataatat
    38581 atgaatatat tatggtgaaa tttatagata tatattaatt atggggagat tgtgggaggt
    38641 tcttttcaca agacatttaa gctatgaaaa taaataaaaa atttaataga gttgatatgc
    38701 aggtttcaat acttactgca attattgtaa taatatcttc ctcatgtgta tattttttta
    38761 attatacatt aacttataag agcatgatat actctttaag tgagaggtca aaacatatct
    38821 atgaatatgt agagagaaat attgataaaa atacctttac tgaaattaat tctaaagaag
    38881 accaatcaaa aaagtcttat aaaagttcta aaatcctatt agaatctgta aaaaatacta
    38941 ctggagtcat gtatctatat actgctaaaa aaacaaaaga tggatcacta gtatatgttg
    39001 ttgatggttt aaattcatct agaagtgatt ttagaaatgc tggtgatttg atagaaaaag
    39061 agatttgggg agatcttaac aaagcattag ataatcatat attgttacct aaaaagatta
    39121 aatcaacatc ttggggatac atatttatat cgtattttcc tattcacaat gatgttggta
    39181 aggttgttgg agtaatagga attgaatttg aagcaaaaca tcaatacaat acatttaaat
    39241 ttataagtat agttacacca ataatagcat tattaacttg tctaatatca gcattgattg
    39301 cagtgattct atttaaaaga atatctaatc ctacatatac tgattttgct aatacagatt
    39361 atttaacagg cctaaaaaat agaaatgctt ttgaaataga tatgaataac ttaaacaatt
    39421 caaatctaaa gaatctaata tctatcatat caatagattt agacggttta aaaaagatta
    39481 atgataaatt tggccatcag acaggagact tatatattaa gcaagcaagt aaaattatac
    39541 aagatgtaat aaataaaaaa tatatagttt atcgtattgg aggtgatgaa tacataatta
    39601 ttctaaaaaa tttatctcac aaagaaataa atagtattat aaataatatt aatttaaaaa
    39661 tagttgaaga aaactcaact aatgaattaa aattatcaat gtctattgga tatgctattt
    39721 ttgatgaaaa agtagatgtt tctttatttg atacatatcg tcgtgcagat tctcaaatgt
    39781 atgataacaa aaagaaaatt aataaataat atcaataata aatttaaaaa gtctattctt
    39841 taaataataa atcataagaa tagacttttt aaatttgtgt ttttataaga taaattattt
    39901 aattaaagtt tgttcttttt tctaaacgat tctttataaa ttcatatatt actttcacta
    39961 atatatttgt gactaatatt aacacagcta gtgctgctgc ctgtgcagta ctccccttat
    40021 catctagttg tacaattgat attgcagcta cttttgaact tgcagtatat ataaaaacta
    40081 gtgctgatat tgtcaccata gagtttagaa aaaagtacat aaagttctct aaaactgctg
    40141 gcaaacaaag tggtatagtt acgttcttaa gaattgatgc gctgtttatt cccattgatt
    40201 tagctaccat gtccaattct ttatctactt tcttaatagc agtagtagct gttataaatg
    40261 ctactgaaaa gaaatgaact atattacata taaccattat aagtaatgtt ccatataatc
    40321 cattaaacaa atttttaatg tatattgtat ccataaaatt aaactctaat ttattaaaaa
    40381 ataatacata agctatacct aaaactaatc ctggcaatgc cataggcaat gtacttaaaa
    40441 aatacccaaa tgattttaaa tatggagctt tttctgtttt ttcatttaaa tatgcaaata
    40501 agaaaacaaa gctcgtccct agaatagctg tcaatagtga catttttatt gaatttataa
    40561 atggtttaat tccatcaata ctgtttttca tagaaaagtg ttccagtgta agtcttaaat
    40621 catatggcca aactgatatt aatgaggata agattacagt taacattaca gctattatac
    40681 caaatgcaat aattcctaca acccctccta aaatactatc tcttaactta ttagttttaa
    40741 ccttatatgg aattgacttt gaagttatat atgagttttg atttttttca atttttttag
    40801 ttactataaa cgatattatt gcaggtatta aaagtaatat tgatacagtt gctcccattg
    40861 gcatattctg ttgccctata atttgcttat atacatctat tgataataca ttaaactctc
    40921 ctcctatcac ctttggagct ccaaaatctg taaaacataa tgtaaatgat acgaatgcag
    40981 aacttattaa agagtatttt atacttggga ttgttatgct tataaattct cttatcttgc
    41041 ttatccccat agtattacta gcttcatata gtctataatc ggttgaactt agagatatat
    41101 aaagtatttg aaaggattga ggaaatacat atataatttg tgccaatatt attcccactg
    41161 ctccatatat tggaacatgc actccaagta aattagttac caaaccttga tttccaaata
    41221 aatatactag acctattgca tgcatcattg ttggagcaaa cataggaaac atagctaatg
    41281 atttaaaaaa acctttaaat ttaatctttg ttctagttaa tgcatatgca tatactaatg
    41341 caagtgttag tgatattaca gttgatataa ctgatacaaa tactgtattt tttagagaat
    41401 ttaatagaga ttcagaagcc aagtattctt gaaagttttg taatcctaca aagactccat
    41461 ctttatctaa aaaagcctgt acaaatagat atattatagg tgctaataaa aatattacta
    41521 aagacataac taatactgta agcatacatt tttttatatc taaattcatt tttgatttaa
    41581 gacttatact tttagaactt atagcattat tattcataca cttatgctcc tttaactttt
    41641 ggatacttta aatagtattt ttcgtctata cttattttta caaggtcacc ttctactaaa
    41701 tttaaattaa cccactcttt tatagaaaca tcacttatta tgaaattttc atttaattta
    41761 tcttttattt caactctcaa taaattccct ctaaactcta tatttgatat tataccttgg
    41821 tagttttctt ttgtcgattt ctctatttga acatattctg gtcttacagt taatatagaa
    41881 tctccattat caaaacagtt tgtatctcct ataaattgag ctgtaaatag gttttgagga
    41941 ttttggtata tttcttctgg agtccctatt tgcattatat ctcctccatt tagaatagct
    42001 attttatctg ccatagttat agcttcttct tggtcatgtg ttaccattat tgtcgttata
    42061 ttaagttctt tttgtaatct tttaatgtcc attctaagct tgtgtctaac ctttgcatct
    42121 aatgcggaca ttggttcatc taaaagtaaa aactttggtt caagagctaa tgctcttgct
    42181 attgcaatcc tctgttgttg cccacctgat aatgctttag gatatttatg agcttcatta
    42241 gtcaatccaa ctgtttcaag tacttcctta actttattat ctattttttc ttttgaaact
    42301 tttctctctt ttagtggaaa agctatattg ttataagcag tcatattcgg aaataatgca
    42361 tatgattgaa atactatacc aaaacctctc tttgatggct ctaaatttgt aatatcttta
    42421 tcctggagaa ttatagttcc actatttaca tcttcaagac ctgctattat tctaagtaat
    42481 gtagttttac cacatccact aggtccgagt aaacatagaa attccccttc ttcaatatcc
    42541 aaactaatat tatttaaaac ccttttttgg tcataacttt taaacacatt atttattttt
    42601 aagtaactca tatcttatct ctccttatat agttattttt ttattttaaa ttttatatcc
    42661 tactttttct tctaaaattc tttcatctaa attattaatt taaaccttac ttactttcag
    42721 attttgaacc gtattttgat tcccaagttt taagtactgt acttctgttt ttggcagcag
    42781 agtttaaatc aacttctttt ataagctgtt caaatggttg tttagaataa ccttttggaa
    42841 ctggattata tgtctttatg gaagtaactg ctacttcatg tgcatatcta tccatagctg
    42901 aatcacttat tgcccaatct aaaaatagct ttgcttcttt ttttatatta tcttttttaa
    42961 ctaaggcatt tgcttctaag tcccaacctg aaccttcctt tggaaataca acctctatag
    43021 gttctccact agataattgt tgtgtagctc tatatccaag tgtaatacct attggatact
    43081 ctccagagcc agctaacttc gcaggttttg aacctgagtg tgtatatgta gctatatttt
    43141 tatgtaattt atccatgtaa ttgtaagcat ctttttcacc catcatttga ataagccctg
    43201 atactgtaag ataccccgtt ccagatgatg ctggatttgg cattgttata agtcctttat
    43261 attctggttt tattaaatct tcataacttt ttggaatatc tatacctagt ttcttaagtt
    43321 ccttataatt aactactatt gctgtctctg ggacactcat tcctacccaa gatacatcat
    43381 cttcagtatc tttaaatttt ttatcaactt tatcataatt tttaggctta tatgcttcaa
    43441 gtgcaccatc tttttttagc tctatcatgt tcattgctga taatccccat ataatatctg
    43501 cttgtggatt atctttttct gctaatagtt ttgaagctat tacaccatga gaatccataa
    43561 ctatctctac atctatattg ggatactctt ctctaaaacc ttccatataa taagctatct
    43621 gctcttcctc tagtgctgca tatattgtaa gtttattatt tccttttcct tgagtagttt
    43681 gtggtgttgt tgatatgcaa cttgtcataa atgtaatcac tacaatgcac agacaagtaa
    43741 atataaattc tttcatatct tccccctttg tgttttttcc tttttttatt tgttttttat
    43801 tgtttttgct tatgtttata taatacacct aatttgttaa tataaagtta agtgtaaatt
    43861 aacagttcgt taatttttag aaatttttgt taaatatatt atttttagtt aaatacagtc
    43921 tgtttttaaa caatatatta atttttatag tatctacatt ttaatttaaa cataaaaaat
    43981 aagtctaacc tctataaagt agaatgttag acttattttt ataagtattt aattatacaa
    44041 ccaaatcatt ttttttcttt tcttcaagtg cttttttaag caccatatcc ttaaccttca
    44101 taagtctagt agtacttgct ctctcatttt cttcaagctt catagctata tacttaatag
    44161 tctcaatgta atttggtatc attacatttt caagagcatt aacacgtcta cgtgtctttt
    44221 ctatctcttg tgcaagaagc tgtgcacttt tttcactttc tgcaagtctt aaaagtggtt
    44281 gcatagcatc tgagaaagct tccatagcag aatctaattc acctgatgta aaagcaagac
    44341 cataaggata aatatcactt tgattgtttt cagttttaaa gtcaaacaca ggaacatcaa
    44401 cactcattat atttctcgta gaaacatcta ctgaaactga ttgctttggc atcataagtg
    44461 ctgaacccag atactcctga ctcataactg ctcttgcgat tataaagttt ttataagcag
    44521 tatcaagagc attttctgct tcttcacgca atcgcttatt ttctcttaca atctcaagaa
    44581 attgtttcat aagttcatca agtttatctt taagaagctt atgacctctt gtagcagttt
    44641 taaggagttt cttaagtcta gtcatttcca tacgtgttgg atttatattt aatctagcca
    44701 cagatatcac tccttaggca tatatttttc aaaatattca tcacggatac gtttaagttc
    44761 actttttggt aacatactaa gaagcttcca tccgatttct aatgtctgct caatagttct
    44821 atcagttcta aatccttgtg aaacatattc tttctcaaat tcatctgcaa acttagcata
    44881 cattaaatca atctcagaaa gtgcagattc accaagtata gccataagtt cttttgcatc
    44941 cttacctctt gaataagctg caaaaagctg gttcattgta tctgcatggt cttcacgagt
    45001 cttaccttta ccaatacctt tatcttttag acgagaaagt gatggtaaaa catctatagg
    45061 aggctgtata tcttttttat aaagttcacg gctaagtata atttgccctt ctgtaatgta
    45121 tcctgtaagg tcaggaattg gatgtgtctt atcatcctca ggcattgtaa gtattggaat
    45181 catagttata gacccttcat gccctttcat ttttcctgct ctttcataca tagtagcaag
    45241 gtcagtataa agatatcctg gatatccacg acgtcctgga acttcttttt tagctgctga
    45301 aacttcacgc aatgcctctg catagtttgt aatatccgtt attataacaa gtacatgcat
    45361 atcttgctca aaagcaaggt attctgctgc tgtaagtgcc attctaggtg tagatacacg
    45421 ctctacagct gggtcatttg caaggtttac aaacactaca gaacggtcga ttgcaccagt
    45481 tgctttaaaa tcgcttataa aaaattcagc atcttcaaaa gttataccaa ctgcagcaaa
    45541 tacaacggcg aacttagaat cagttccacg tacttttgcc tgtcttgcaa tctgaactgc
    45601 aagattggca tgtggcaaac cagaccctga gaatatagga agtttttgcc ctctaaccaa
    45661 tgtattaagt ccatctatag cagagactcc agtttgtata aattcggccg gataatcacg
    45721 tgctgctgga tttattggag ctccatttat atcaagtctt ttatctggta taatttctgg
    45781 acctccatca ataggtctac ccattccact aaaaacacgg cctaatatat ctggtgaaac
    45841 tccaaagtca agactctttc ctaaaaaacg aactttactt tcagcaaggt ttatacctgt
    45901 tgagctttcg aaaagctgaa caagtgcagt atctccattt acctctagaa ctttgcaacg
    45961 gcgaatttct ccatttgaaa gttcaatttc tccaagttca tcaaatttta caccttctac
    46021 gccgtttatt aacataagag gaccggctac ctcttgtatt gacttatatt cctttatcat
    46081 agttcttcag cccccctctt tttaataagg tctgcaagct cgttgtctat ttcatcttca
    46141 attgaatcat aagctgcatc tatatcgcct tcttctacat acttagcacg accaatcttt
    46201 tcaagaactg aaagcttgat aatatcgttt atagtaacat tttgcttgat agcatcttgt
    46261 gctgacttat agaattttaa tataagtccc atcattctat attgtttatg aagtgatgta
    46321 taagtatcaa cttcatggaa agagttttga tgaaggaagt cttctcttat agaacgagta
    46381 acctctagta tcaatctatc tccatctgaa agtgaatcaa ccccaaccaa ttgaactatt
    46441 tcttgaagtt cagattcaac ttgtaaaagt ttcatagctt gagctctttg agctgagaaa
    46501 ttatcattta catttttatc tgcccataca tcaacttttt cctgatagag tgaataacta
    46561 gtcaaccagt taattgctgg gaaatgacgt ttatatgcta aagatgcatc aagaccccag
    46621 aatactttta ctatacgaag cgttgcttgg ctgacaggtt ctgatgtatc accaccagga
    46681 ggagaaactg caccaattgc tgtaagtgtt ccttctcttt catccatacc tagacaattt
    46741 acctttcctg ctctctcata gaattgagca agacgtgaac ctaagtatgc aggataacct
    46801 tcttcaccag gcatctcctc taaacgacca ctcatctctc taagagcctc agcccatctt
    46861 gatgtagagt ctgccataag tgcaacacta tatcccatat ctctaaaata ttcagctatt
    46921 gtaataccag tgtatataga agcttcacgt gcagcaactg gcatatctga tgtatttgct
    46981 ataagcacag ttctttgcat aagtgactcg cctgttcttg ggtcttttaa ttcaggaaat
    47041 tcaagaagaa catctgtcat ttcatttcca cgctcgccac agcctatata tacaactata
    47101 tctgcatctg cccatttagc aagctgatgc tgtgtaacag tttttccact tccaaaaggt
    47161 cccggtatag ctgctacccc accttttgtg attgggaaaa atgtatctat aactctttga
    47221 cctgtaacaa gaagtgaatc tggtgttttc ttttctctat atggtctttc ttttctaact
    47281 ggccattttt gcatcatagt tacaggtata tcattacctt tttcatctgt aataacacaa
    47341 actgtatctt caacagtaaa ttcaccagaa tatatttctt ttatagtacc cttaactcca
    47401 taaggaacca taattttaca ttctactact gctgtttctt gaacgccacc aattatatct
    47461 cctgctacaa ccttatcacc aacagatttt ttaggtttaa attcccactt agttgttcta
    47521 tcaagtgaag atacttcaac acctttagtt atattagtac ctgaaatatc atacattttt
    47581 tcaagtggac gttgaatacc atcataaata gttgaaataa gacctggtcc aagttcaaca
    47641 ctcataggca ttccaagaga aactacttct tcccctggtc ctagaccgga agtttcctca
    47701 taaacctgta tagaagcttt atctccatgc atttctataa tctcgcctat aagatgttta
    47761 tctgaaactc ttacgacgtc aaacatattc gcatctctca tgccctccgc tacaacaagc
    47821 ggtcctgaca cctttacaat tgtgcctgtt ttcatattct ctcacctgca atcatatact
    47881 ttatcaaaat ttaaatattc cctcctatat tttattagca catatcttta gcaccaataa
    47941 aatttgagat tgtcttttat tcaactttca tctattcttt aaataatata tctgcaccta
    48001 tagcacgttt actagattct cttacttcat tcatacctaa tcccatactt cctccaatac
    48061 ctggaataac tataatggca ggaagttggt aatctttgta ttttgctatt gattcttttg
    48121 caagcaatga tgcctgttct gtaatataaa ttatcgcata ttcatcttca accaacttat
    48181 gtatactttt tttaatttcg tcactatcat aggctgggaa gatatctatt ccaagagcta
    48241 aaaatcccat gatgctatct ttatctccaa ctactcctac cttatacata agcatccctt
    48301 agcctttctt ttatagtatc tgcgtctata ttattaagct tactagtcaa aataattcta
    48361 attgttttta tctctgattc tttagcatat aaatatgcaa ttagtggttc taatgtaaga
    48421 ggcttaaatt ttgctcctct aacatattcc ataagatagt catcacaaag tttttcaaag
    48481 acagtaaaac cactatccat gccattttta cagacatcag agtaagaagt agatttaaaa
    48541 catgatgctg gagtatctga ggaaaaagct tctaagaatt tttccttatc aagtgagcca
    48601 cctgaaacaa acacattcat aaacatatca aaatctttct tcatattttt gactcttata
    48661 aaactcttta gatttgttaa atcgcaaact ttcataacat aatctattac aaatttgttt
    48721 tggctttctt tagcagtttc tttcatactg gtaaaggttg ctttatctag aacaatatca
    48781 accatctggc cattttgtgt cttattataa acatcaaatg cctctaatat agctgatgac
    48841 attatcttag gtaaatcact aaaactacga tttgctaaag attctctaag cttaataaga
    48901 ggaattgtac ctccatcaat taaatatttc tcaccatcta caccagaaat ttcttcttta
    48961 atcagcactt ttaaattgtg atagtcattt ttataaagaa atacatcaac aaatttttct
    49021 tcaggagcta gacttttaag aatttcatat gtctttgata attcttgagt caaaatattc
    49081 tcaaaattat gtatattatt atttgatgta tcagcataac ctgcctcagc tataattctt
    49141 aaagagtctt cagggctttt ggcttctgcc atttgaataa acatttgtct gttaagaagc
    49201 tgtttttcaa gcactcttat tcgtgcaacg gcatagggat aagttttttc ttctgccatt
    49261 ttttaacccc tccttaatta aacaaaattt ctgctgcaat ttgttcaata tattcatgct
    49321 ctactgcaat tatggcttca aatgaataat tgtactcaat gtcacctttt ttaactatga
    49381 aacctccagt aatatctcta gtttcatcag acactttaat gccttttttt gatagcacat
    49441 cttttaatgt ttttttatct tttttagata atactatctc tgaatcatct gtacaatttg
    49501 atttttcaat catgtttagt ataatctctt catattcatt atctttaaga tttaaaagtt
    49561 tgtttttagc ttctaaaatt acctcttcta aaatctcttg tttttttgat aatatttgct
    49621 ttttagcctc catataagct cctgatattt ccttagaagc cgctttttct gcttctgcct
    49681 ctgcaagctt tgtataggaa gccatttcct tttcagcttt ttcattagct gaatttactt
    49741 ttaaatctgc ttcactttta gctttatcca atatttcttg tgcttcttgt ttggcatcag
    49801 ctataattct gtcaatcatt ttttgttcat tacccatagg agtgcttcct ccttttcatt
    49861 ttttttactt atgaattata atttataatt aaccaattgc aattccattg taagctaaga
    49921 aagaaacaag tagtcctaaa agagcatatg tttcaactat tgctgcaaat gttatagctt
    49981 taccaagttc ttcaggtctt tttgcaacta ttccaactcc tgctgctgct gctttacctt
    50041 gtgctatacc tgatactaaa ccaactaaac caattggaag tcctgccata agaagttgta
    50101 aaccttgagc tgatgttggt attgcatctc caccaataat ccctgctttt gataaaataa
    50161 ggaaagctat gataaatcca tacagacctt gtgtaccagg aagaagttgt aaaactagaa
    50221 gttgaccgaa tttactaggg tcttctgtta caacacctgc tgcggcttga cctgctattg
    50281 aagtaccttt agcagaaccc atacctgcaa ataatgctgc tatagcagct cctgatattg
    50341 ccaaaaattg accatttcct aacgcgttta aaaattccat atttacatct cctttttatt
    50401 aatgcttgta tattttgttt tatacttaaa cggaacaaaa ggaactcctc cgccttcata
    50461 aaacttattg aaaaattcta catactgtaa cctacttgta tgaacatatg cacctagtgc
    50521 atttataaga aggtttattg tgtgtcctac aacaccgatt acaactgcaa gtatcggacc
    50581 agctatagcc cctaaaaggt tgataacttg tgctataact cctgttgtta aacaaagcgc
    50641 cataattctt gtataagata atatatcagc aaaataactt gttatgccat agagacttga
    50701 aaatccttta aaaagcttaa caggaatacc tttaaagctt cttccttgag taagtacaag
    50761 acctatagca cctataattg ctaaatattt tcctacttct gaaaatacac ctatgtcccc
    50821 tgcaacaaaa ggtattataa gtagacatac acctgttata cacaaatacc aaaaacctat
    50881 gtcaaagatt gcatctatta cctttccact tcttattaat gtatatgctt ttattcccaa
    50941 acctacatat atatggataa taccgaacag taacgacatt cccataagtg tcataacatc
    51001 ctctaaagga ttaattaatg cttttatagg aattaaatcc cccaaaatac ccccgaatat
    51061 aagaccccat acagtagttg aaactccaca gataccaata agtttaatta aatttccttc
    51121 acctttttgt atctttaatt tatatacaac aaatccacag actactgcaa ttattaaccc
    51181 atatgcggcg tcacttagca tcattccaaa gaatacaaca aagaagaaag ttaaaattgt
    51241 atttgggtca atatcttttg tacttggata gctgtacatg ttagttacac tttcaaaagg
    51301 tgttactaat ttattgtttt caagcagaat tgggaagcct tcttctttac ttccttcttc
    51361 agtctgaaca caacaatcaa acttttctgt aatttcttta attaattcat ctgccctttt
    51421 gcttggtaac caaccattaa gacagaatgt tgtttttgtt ttgacaagtc tctctataat
    51481 ctttttttgg tctctttcta tagtgtaaaa atcatatagg ttttcaagca tgtgtatact
    51541 atctgcatgt cttttaattt cctctgtttt gtccttagaa acgttttcct gcctaattat
    51601 catttcattg tatttcttga tagcttgtaa cggtgtacct tcttcatttg gtaatgaaac
    51661 cactgaaaaa ttaaattctt ttaaaacttc taaaacatca tcaaaagttt cttttaaagt
    51721 aattaaataa acatagttca ttaacttgtc agaattgaca atcccaataa cactttctgg
    51781 tatttcatct tctaatttta ctcttaaagc atcaatattt gcgcttatgg gcacagttcc
    51841 aagtatagtt tttgtatact tagtttccat attttcaaga ggaatatcaa agttcaccca
    51901 tggttctaac atacttttat tgttgttaag taagtttatg ttagacctta ttgtacctat
    51961 ctccttgtgc aaattgttta actccagagc ttcagcataa acttgccctt ctttttcact
    52021 atcaattttg ttaaactctc tttttggtgc aagtagggat tttttttgtt tcactagtga
    52081 agaaacaata ttaattgctt ggtttacatg agacattttc tgctctagca ttataacttc
    52141 agattcttca ctatctttta caagataatt ttttaattcc tcctcctcag taagaaaggc
    52201 actatcatca atctgaacaa acccacggtt cataagtagc tttaaaatct ggcttttttg
    52261 agcttctaag ccaacaatag atattttgtt catattaact attgccatat tatctcacta
    52321 cctttccaat aaccgcttca atagccttac tttttctttc ttcagcagtt ttttcaattt
    52381 tcagacattc acttttagca ttagctaaga ttttatcaac ctctgctcta ctgtcggtga
    52441 ctgccttctc aataagagtt tcttccataa gctttgcttg ttttcttaca tcagcaaata
    52501 tgctttcaca tttgtttaca gcatcagctc tgatagactc tgcatcagta acagctttta
    52561 ctttgatact gtctgctgtc tgctctgcct caacaatgct ttttattatt tcaaaagcca
    52621 tccaaatcac ctctcttacc tttttactat gtatataacc aattagattt ttttattcta
    52681 attagattac tacctcattg ttaaagtata aacagcattt ttatataata attaatattt
    52741 ttcaacgttt atttcttaat aaaacatatt ttagaatagt acttgcctag atttacatcc
    52801 ttttttgact tacttttaga ctatgacatg agtatggttt ttaaatacca ttattttcaa
    52861 taattataat ttaaagcgat atagtttgtc aatagcgtta ttttgtttta aaattaacgc
    52921 tatgtcgaca ttttaaattt ttattttatt ttttttataa ttttaattta atttattaca
    52981 tataaaagtt ttttatattc tttttcaacc tctaaccctt gaagtttatt gttttttttg
    53041 aatttttaga aatatctcgc actattttat ctaactttta taaatcatca agctatatcg
    53101 atttttgtca ccttattttc aatctaaatt ttttatatat agttagaaat aaatcaatat
    53161 ttttaaagat tgataaaact tacacttagt tctaatagtt ttattttaag gcaatgtatt
    53221 aatcttaagt agataatatc attagttact ctatatattc gacaacatta taaaaaaatc
    53281 ctcgtaccaa tcactccaat cttcaatagg atatgctgct cctccattta cacttttcag
    53341 taggtttgat gtatattctt ctcccatgga aaaaagttcc cctactgtta tatcataacc
    53401 tctagatgta acaaccttac aaaatgaatc cataacatca cgttgttctc ttgtttttat
    53461 aagttccttt ctaaattcat catcattctt agcttcttct aaaattttag ttaatttttc
    53521 attcattatg tatttctcct tttaagtagt ctttctgtaa acttcaataa gctttatata
    53581 aaaaggaagc catcctaaat aaactaagat gacttcgctt aactgttagc aacacattta
    53641 ctagtataaa ataattggtg tacctggttc tatattttca tatattttct ttgccttaga
    53701 aaaaggtgta tttacacatc catgtgaacc tgaagactta tatatacctc caccaaaaga
    53761 atttctccaa gtagcatcat gaatgcctat gttcccatta aatggaagcc aataacttac
    53821 aggtgaactg taaccttgac cagttaatga aacatttcta gccttataat taagaggata
    53881 tatacctgat ggtgtagcaa atcctctagc taaatcgcct gttacaacat ctgttgatac
    53941 aagcatttct ccatttttaa agaaccacat atgttggcca gaaagactaa tctctacata
    54001 tgtatttcca atatcatctt tattacgaga tacagctttt tgtatgtaaa taggttctct
    54061 tgtaacattt ttaccagctt ttacaacatc aactaatgct tcagcttctt tctttttatc
    54121 tatcaaccaa ccataaattc cacctgaaat tgtaatatct ttacctgtgg cagttttaaa
    54181 tggtcttgag tcaccaaaag tactgtattt tttacttaaa cttcttgtat attctaccat
    54241 agcatcatta tcaaaagtta tgtcataatt cttttctgag tctactttta accatttatt
    54301 aatttcagaa ccatctaaag tttccttacg gtcactaaaa tcatatgtaa cgactacacc
    54361 aacatactta tctaatgtct taatagcttg tttcaacttt tctgaatcct ttgtgttgtt
    54421 tggtgcttca taaactttac tttcatccag agaaatagaa gtattcccag aattaattga
    54481 gttttgtact aacttataaa aatcatcttt tttcactttg tttccaagta cctctggtac
    54541 tataacataa gcgtttttag tgctatcata cttaggataa gcactcttag gttctacaac
    54601 atttttacta tcaaaacaag ataaagcatt aaaccttttt tctagtaaat ctttattata
    54661 tgaaagagtt atcatattat tatactcttt agatttaaat attccaccaa tccatccaat
    54721 agcgctttga ctatctttta tcttttgaac tttatcatct ggtgtaaatt ttaaatcaat
    54781 atcttttgct tttatttgtt ctttcttatt gtttctttcc tctaagttta aagtatagga
    54841 attagtacta gatgttaaca aatcatttac ttgctcaact gtttttcctg aagcctttac
    54901 gccattaata gtcgttccaa agtaaaaatg atttctaaaa aagattgcca ttcctatata
    54961 agctacaaac aaaacaccta caactatagc tatcttaaat tttagatttt tttgtccact
    55021 ttcttgtttt acctcttttc catcaatcat aattaaatcc ttccttacat tgtaattacc
    55081 tatgtacttt attggttttt aaacaaaacc atgtatgcct tattttatat acccaaatta
    55141 ctgtatcatt gtttatattt ttaaatatat agttatttcc ataaaaccat tttatctttt
    55201 agacaaaatg actattataa atcacccctt tcaaaatccc ttaaatacaa tctctgctat
    55261 attaatatat taccatactt ttaataatcg tgggttatct atctgttttt gtaacactaa
    55321 actactcttt taaaaaagaa actaatttta tgttagtttc tttatcttaa cttattttta
    55381 tattgaattt tagcttaaca taacgttgtt atatagattc tatttaatta ttttagtttc
    55441 tatatctttt ccatcagcat attctttaag taactcctta gcatatccaa aatattcttc
    55501 aatatcagat tcttgactaa aagaaaatat acaaattaat atttcatttg catcttctgt
    55561 tatcattgct ctttcagaat cactagttgg actcccaaat ttacccactg aatcagacaa
    55621 tataggaaga ttttctatat ttattaattc tttcccaata cccttatact gttctccttc
    55681 atctcctaca gtaaaacata ctggtgaatg taatttgctt acattatatg tacctactgg
    55741 atataatgat tttattgata ttaaattgtt tatttctact atattattta ttgtataaag
    55801 acccttccct tgaataattc ttctaaccaa tgcttctgaa gatgttctat atctacttgg
    55861 attttttcca agctctttat aagcatttct tgcatcttta attttatcta gtttcgtaat
    55921 gtcttcaact tttagacttt gatttatagt atcacaaaac tcatttattt cattaattaa
    55981 tttttctgag cttttattta ctgctacttt tgcttgaatg caacccaact tagcattagg
    56041 ccatctttcc ttaagtttgt catcaatact cacatctatc atacttaaac aactcctata
    56101 cactaaattt ttattaaagt ttttatcatc tatacattat agtactattc ttttgttaat
    56161 aacatgttta ttagcaaaat aaatttattt ttaatataat ttttataaaa tacaattatt
    56221 ttttgcttta tattaaacaa tacattgata aaataaaaaa acactaatta tttagcagtg
    56281 atttattaaa atcaaacatt cataatagtg ctttatataa aaattaaatt ttgttttaaa
    56341 gtaaatctaa aaaattctta gctggcattg gtcgtgcaaa ataaaatcct tgaactaaat
    56401 cacatccaaa ttgtttcatt aactcagctt gttctttact ctcaacacct tctataatta
    56461 caactaaatc tagtgatttt gctagagaca ctattgattt tgctatattg cgacttctct
    56521 catcatgttc aataccatta agaaaagact tatctagttt caatatatca attggcatat
    56581 ctcttaaaca actaatagaa gaatatcctg taccaaagtc atccatagaa atagaaaatc
    56641 catacttcct caactcattt aaaacattct ttaaaatatt taactcatta atagccacag
    56701 tttctgttat ctctatttca attaaatctg aacttagatt atacatttgt attgttttat
    56761 tgataaattt tacaatatct ggttgataca actcaactct agataaattt attgaaactg
    56821 gaactatctt tttaccttgc tttttccatt cagataaatc attgcaaacc ctttcaaata
    56881 caaatctccc aatttttaaa atcaacttac ttttctctgc tattggaata aatactgcgg
    56941 gacttataaa accatgttct ggatgattcc atcttattag tgcttcactc cctatcattt
    57001 ctccagttac aagtgaaaac ttaggttgat aatacacttc aaattgattt tttaccaatg
    57061 ctatttttat atcatctaaa atcattgatt cttcactaag cttattccta acatcttcat
    57121 tataaatagc ataatttata tttttacctt tagcaacaga cctagccata tttgctttat
    57181 ttacagcctt ttggatatct acttcacctt cttcaacaaa ataaataccc acacacagag
    57241 aaatttcaaa tactatactc aaattacttt caatattatt tcgtatacta tcaatttttc
    57301 ttatacgttt attttttcca tttttataat cacagaaaat tgcaaaataa tcacttgaaa
    57361 gtcgtgcata tacttcacct tctgttaatt cttcttttaa agcttttgct atcgtaatta
    57421 ataaattgtc accaaattca tatccaaaag tatcattaat catcttaaag ttattaatat
    57481 caaaatatac tataatataa tttaaagatg gtttatctaa aagatactta ctacactctc
    57541 tataaaattt attttgattt cctatatggg taactttatc ttcataagcc aaacttaata
    57601 tttctttttc attggatttt tttatataaa ttatataaaa aataattgca ataaatatta
    57661 atataataaa taacactgca tatatagctc tgttgattat ttgttctgaa ttactaaata
    57721 caacagtttc tggaattgaa aaaatcaaat tccaatcttt tatataatta ttttcactat
    57781 tcccattatc catagtagca tatcctaaat atcttctttc ttccaacata tttaatacag
    57841 ttgcacctgt tttattttct tgcaattctt tttttaatct atttatttct cgaatatcat
    57901 tatcctgttt taacaattta taaatatttt ttgataggct atcctcttgc ggatgaagga
    57961 taattgtacc atcatttctt acaacataag atatactatt attttcataa aaagatacat
    58021 taataagttt catcagagta ttgatattgt aagtacaata taaaactcca actactttat
    58081 cattatttaa taatggtact gaaatagtaa tcttctttat agacttattt acttcatcaa
    58141 catatggact tgaaacatac ttcttacctt taattgagtt tttgaaaaat tctctatctt
    58201 tcactgaaaa cttatcacct ttggtatttt cagcattacc atttatatca actattgcca
    58261 tagtgtaaaa tttttgattt tccatttcat ctaaaagatt tttcattttt tcctcattag
    58321 gtatatcttg atttaaagca taatagttag aaaaaatatt taaaacatct aaatcttttt
    58381 caatttgtct ttgtgctagt tgagagcctt gtactgcaac ttcttttata tgtatttttg
    58441 cctctgacat aagaagatgt tttgtatctt ctatatagat ataccccatt gtcaaaaata
    58501 atgatgttaa aaaaagaatt gtaattaatg taaaactttt atttctccct gtcattcgac
    58561 tcctccccta attagtcaat acttcatata gataatatat cctttttata ccgattcatc
    58621 atttatattg tatataacta ttcttaaatg ttacacataa aatcaaccta ataaccataa
    58681 aaacattctt ttattatcat aataacacta tttagttgaa ttttaaatta aagaataaaa
    58741 actatcaatt tttctaaaca aaaaaactct tatacaataa aactttgttt tatgtataag
    58801 agtttttatt ttatctattt tatagtaaat ttatcttcca taatatgaat ttaaatacat
    58861 atcttttatt tcattcataa gtggatatct tggatttgct cctgtacatt ggtcatcaaa
    58921 tgcttgaatc accatttcat ctattgaatc cataaactta ggttcttcaa ctccaaactc
    58981 ttttatagat ttaggaatac caactttaag ttttaaatct tcaatagcta ccaataaact
    59041 ttggaatttc tcttcatcag aatttccctt taatcctaaa aatgaagcta tttcagcata
    59101 tctttttaat gcttctggat atttatattg agagaatgct cccattttct ttggtgcatc
    59161 tgaagaatta aatttcataa cttctgttat caaaagagca tttgcaacac catgtggtac
    59221 atggtggaaa gcacctaatt tatgagccat agagtgacaa acacccaaaa atgcatttgc
    59281 aaaagccata cctgccattg tagaagcatt tgccattttt tctctagctt ctgggtcttt
    59341 tgcaccatta tcatatgcac gtggaagata ttcaaatata ctcttaatgg cttgtaaagc
    59401 taatccattt gtataatcag ttgcaagcat agatacatat gcttctaatg catgagttaa
    59461 tgcatctata ccagaagcag atgttaagct ttttggcata ttcatcatca tatcagaatc
    59521 aactatagcc atatttggca tcagttcata atctgctaat ggatatttta cccctgtatc
    59581 ttggtcagtt ataacagcaa atggtgttac ttctgaacca gtacctgctg atgttggtat
    59641 agctacaaaa ttagcttttt cacccatttt agggaatgta tatacccttt ttcttatatc
    59701 cataaatctc atagctaggt cttggaaatc tacatctgga tgctcataca atgtccacat
    59761 tatctttcct gcatccattg cacttcctcc acctatagat attattacat ctggattaaa
    59821 ttctctcata gctttagcgc ctatcttagc acattccaaa gttgggtctg gttctacttc
    59881 aaagaatgta gtgtgcttaa tattcatttc atctaataaa tcagtaactg ctttagtata
    59941 tccattattg taaaggaatg tatctgttac aataaaagct ctcttcttat tcattacatc
    60001 tttaagttct tttaatgcta cccctaaaca accttttttg aaataaactt ttcctggtga
    60061 tctaaaccaa agcatatttt ctctcctctc agctactgtt ttaatattaa gtaaatgctt
    60121 aactcctaca ttttcagata ctgaatttcc accccaagac ccacatccta aagtaagaga
    60181 aggagctagt ttaaaattat ataagtcccc tataccacct tgagaagaag gagtattaat
    60241 taaaattcta caagttttca tggctgaagt aaacttatca agtttttctc tttgatttac
    60301 atcatcaata tataatgaag atgtatgccc aaatccacca tcttctacta atttttctgc
    60361 ttttctaact gcattatcaa aatcactggc cttgtacatt gcaagtactg gtgaaagttt
    60421 ctcatgagca aaagcttctt ctatttcaac tgattctact tcacctatta aaaccttagt
    60481 atctactggg acttcaaagc ctgcaagttt tgctatagta caagctgttt gcccaactat
    60541 tttagaattt aatcctccat ttactaaaat tatatttctt attttttctg tttcatcttt
    60601 atctaataaa taagcaccac gctctttaaa ttcttttttg acttcattgt atatattttc
    60661 taatactata accgattgtt cagaagcaca tatcatacca ttgtcaaaag tcttagatac
    60721 aagaattgag tttacagcag tttttatatc tgcactctca tcaattattg ctggagtatt
    60781 acctgcacca actccaatag ctggttttcc agatgaatat gctgatttaa ccattccagg
    60841 acctcctgta gcaagggtca aatccacttc tttcataaca gttgtagtta attctaaaga
    60901 tggctcatct atccatccta ttatgccttc aggagctcca gctaaaacag cagcctcaag
    60961 aacaactttt gcagcctcta tagtagaatt ttttgctctt ggatgcggag agaaaattat
    61021 tccatttcta gtttttaaag ctaaaagtgc tttaaagata gcagtagaag ttggattagt
    61081 tgtaggtaca actgctgcaa taacacctat tggctcagca attttagtca taccaaatgc
    61141 ttcgtctttc tctataacac cacaagtttt agtttcttta tatgcattat atatatactc
    61201 tgaggcataa tgattcttta taaccttatc ttcagcaatt cccataccag tttccttttg
    61261 tgccattata gctagaggaa ctctttgctt attagctgcc aaagatgctg ctaaaaaaat
    61321 tttatctacc tgctcttgag tatatgtagc aaatattttt tgagcttctc tgatttttgc
    61381 tagtttttta actaagcttt caacgttatt tacagtatct aaaccaactg acataacttc
    61441 attttctttt ttattttcta ttattacttg ttctttatga gccattttaa caacctcctg
    61501 agatagtttt ttatttatta tgttaattta ttaacattat agcatttact ttttctattt
    61561 tcaagttatt tttttaacat tttatttttt atctaatata acatcatttc tactaataat
    61621 atctagcttt acaaatactt aatttaacta gatatcactt tattttttac gcaaatcact
    61681 aataaaatca tctaaaaact taaggataac gttatttttt taacgtttat atttttgtat
    61741 tttttgcaaa taaaacttta taaaaagaat ttttaatatg atattctatc aagtttaaaa
    61801 ataaaaatac ttgaaaatga aaataataac ttgattaaca agttaaagta aatatagtta
    61861 aat
//
LOCUS       DAMJYN010000010        59221 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.010, whole genome shotgun sequence.
ACCESSION   DAMJYN010000010 DAMJYN010000000
VERSION     DAMJYN010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 59221)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59221)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59221
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.010"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(64..2127)
                     /locus_tag="PC466_000748"
     CDS             complement(64..2127)
                     /locus_tag="PC466_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF262 domain-containing protein"
                     /protein_id="HDF2768170.1"
                     /translation="MKAGEIEFLSYLEGSNKSFVVPVYQRNYNWKKEQCKRLFDDLED
                     IIDSGFRTHFLGSVVSIYSMGKEYLIIDGQQRVTTVSILLIAMCQIIKEFGESKGIIT
                     TEEQIKECYLINKHSRDKDGKIKLKPIAEDRKAYYELFEEEMNTDRNSNIVSNYLYFY
                     NRIKEDNISIDDLFDAIQKLTIVEIELKNGEDDPQLIFESLNSTGLDLSEADRVRNFV
                     LMGRSSKLQEEFYNNYWYKIEKNTSSNVSSFIRDYLTIKERSIPNKNKVYFSFKRYVS
                     DNGIDIEILLKDLLKFSNYYREISYSCTDDNDVNKVLKRINKLEIFVSYPFILELFND
                     YNEGIINKKVLVESLNLVECFILRRIVCDVPPNALNKVFMNLGREIKKFSDYKENYSN
                     ILRYIFINKKSSQRFPTDSEFSNAFETKDIYNTKSKNKLYILERLENYNNKEIVDLEN
                     LINNNMLNIEHIMPQTLTNKWKESLGDNYKEIHDKYLHTIGNLTLTGYNSKLSNKTFE
                     EKKEMEDGFKDSRLYLNKYISSIDKWNEEEIKNRTKILLDRAVEIWKYPSVTYEPPSN
                     SENIFTLEDDDVNFTNESIVSFSILGESYKAKNWTEFYEQVALTLYDLDSVRFNSIVD
                     KTYKRDFIDNIKSRDVYKLRKGIKISENIYLETNLNTEAKLNIIRFLLNEFDIELNEV
                     IFSIK"
     gene            complement(2508..5843)
                     /locus_tag="PC466_000749"
     CDS             complement(2508..5843)
                     /locus_tag="PC466_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HDF2768171.1"
                     /translation="MGNFDFLQKKKNFNSFNTACLEAEKSILVSPSTCATITRRALEL
                     AVKWLYANDSDLVLPYQDNLSTLIHNNSFIELIDYDMLPLLKYIVKLGNLSVHTSANI
                     ERGEAILSLNNLHQFVSWIDYCYSDEYTAEDFNEDLLLHGEEKRTRPDELKNLYERLS
                     SKDKKLEEVIKENEKLRKSLTEKRKVNTVNYDFKIDEVNEFETRKRYINIELKLAGWE
                     FGKDIGEEIEVQGMPNESGVGYVDYVLYGENGKPLAVVEAKRTSKDPKIGQQQAKLYA
                     DCLEKRYSQRPVIFLTNGFDMYIWDDYSDRKVYGFYKKSELQLMIDRRKSKKSLSSVT
                     INDEISNRYYQKEAIRAVCEALENKQRKTLLVCATGTGKTRIAISIVDVLSRHNWIKN
                     ILFLADRKALVKQAKKSFTKLLPNLALCNLLDSKDSPEDARMIFSTYPTMMNAIDDTK
                     SKDGKRLFTPGHFDLIIIDESHRSIYKKYKSIFDYFDSYLMGLTATPKDEIDKNTYSV
                     FDMENGVPTYAYEYNKAVEDGYLVDYTSIEFKTKIMEDGIKYDELSDEEKEEYENTFN
                     DDESIGDEIGNNAVNEWLFNSDTIDLVLNKLMTEGLKIEGEEKIGKTIIFAKNTKHAR
                     AIVERFNKLYPKYGGNFVKAVDYSINYVDSIIDDFSDKNKLPQIAVSVDMLDTGIDIP
                     EILNLVFFKKVRSKTKFWQMIGRGTRLCPDLLGVDMDKERFLIFDFCNNFEFFKFNPK
                     GFEGNKAETLTEKLFNIKVSMVKELQDIKYIEGKYAELRKELLEELITSVKALNEDSY
                     IVRMNLSYVHKYKNENVWSNIGAVAQNEIREYISPLITSYSDDELAKRFDVVMYNIQL
                     AYLQNNNASKGIRHVMVTAEKLSKLGTIPQIQQQKYTIEKAMTEDFWEDSDIFEVEEV
                     RISLRELIKYLEKSSQKIYYTSFEDMIVAEDRNDSVYNANNLKNYKKKVEYYLNSHKD
                     ELAIFKLRNNKKITKQDVETLEEILLKQLGNCDDYKKEFGDTPVSQLVRKLVGLDREA
                     ANEAFSEFLNNKSFNTKQIHFVKLIVDYVVKNGFIEDNKVLMEDPFRTVGSIIDLFEN
                     HIEERNKLIKTINKIKENASEIG"
     gene            complement(5893..6321)
                     /locus_tag="PC466_000750"
     CDS             complement(5893..6321)
                     /locus_tag="PC466_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768172.1"
                     /translation="MVIRNKLSWNSIEEVNRDFGSCLYDLQNFKILYDKEEMPELWAR
                     YIKEGFKSYMVSFLELTKAMLYYKSIDLNIKSKNFYDYLLACEYHNLLPKNSSIVIET
                     LRKLRNDDSHGYDIPQFEDMYELFTENEEVFVSIRNSCKK"
     gene            complement(6311..6691)
                     /locus_tag="PC466_000751"
     CDS             complement(6311..6691)
                     /locus_tag="PC466_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HDF2768173.1"
                     /translation="MRNIPNEIKNSIINVFPKENTLAIIIFGSYGTDKHTSESDIDIA
                     WIPIKKVPITELATKTEALRNILDIDVDLKIVTDNYTIALKKAILEGEVIYESKDFKD
                     YINKFYFENSDVIDILDWRDMYGN"
     gene            complement(6724..7032)
                     /locus_tag="PC466_000752"
     CDS             complement(6724..7032)
                     /locus_tag="PC466_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768174.1"
                     /translation="MNQIELDLYHDMVNIYKEADLQCNYKPTRFLQLINNKGALLAAK
                     ELINKEGATEGFTRLWECKRLDLSLEVLVLKEKYKELFTDEEREICINRLKDYGYKFN
                     "
     gene            complement(7065..8249)
                     /locus_tag="PC466_000753"
     CDS             complement(7065..8249)
                     /locus_tag="PC466_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HDF2768175.1"
                     /translation="MVDEAKILDVVSISRENVKKFDGERSYLSTGNLDFNKISNLEIV
                     TYENKPSRANQTVNIGEVIFAKMKDTKKTLVINKTNKNIIVSTGFYVLKPSKEILPQY
                     LYHYLNSSYFLNQKNRLSKGATQSALNNEGLANIKIRMYNLKVQEKVVRVLDKAQELI
                     DKRKEQIEVLDELVKSRFIEMFGTPSKNEKNWEISEIGKYLDVLTDYHSNGSYETLRD
                     NVTLLDTKGYALMVRTTDLENNNFEKGVKYIDEHAYNYLEKSKVFGGEVIINKIGSAG
                     KVYLMPFLNKPVSLAMNQFMLRFNEDKVNHIFLYNLLLTSYMESKIKEKVRGAVTKTI
                     TKDAVRKINIIVPPIRLQNQFANFVKQVNSLKFEMETSLKELEDNFNSLMQKAFKGEL
                     FN"
     gene            complement(8253..9716)
                     /locus_tag="PC466_000754"
     CDS             complement(8253..9716)
                     /locus_tag="PC466_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HDF2768176.1"
                     /translation="MITGELRSKVDKIWETFWTGGLTNPLEVIEQFTYLLFIKGLDEV
                     ETKNEAEATLLGVSFEKIFDDEHQHLRWSKFSNEGNSEKMYEIVQNEVFPFIKKLHGN
                     KESAYAKYMGDAIFKIPTPLMLSKIVDGISNLELSKDRDTKGDLYEYLLSKVATAGTN
                     GQFRTPRHIIDMIVRLIKPTPEDIIVDPAAGSAGFLVSSQQYLRDNHSSLFLVQGLKE
                     HFNNGMFYGFDMDRTMLRIGAMNMMLHGVDNPNIEYKDSLSEVNTDKDKFTLVLANPP
                     FKGSLDYEAVSADLLKVTKTKKTELLFLALFLRVLKIGGRCACIVPDGVLFGSTGGHK
                     SIRKEIVDNHKLEAIISMPSGVFKPYAGVSTAIMIFTKTGTGGTDKVWFYDMKADGYS
                     LDDKRNEIKDSDIEDIIKRFDNLDGEVDRKRTEQSFFVDVEEIRENGYDLSINKYKEV
                     VYEEVVYDAPSVIIGRVKVLEKEIVDGLEELERMLEV"
     gene            complement(10226..11095)
                     /locus_tag="PC466_000755"
     CDS             complement(10226..11095)
                     /locus_tag="PC466_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit GatY"
                     /protein_id="HDF2768177.1"
                     /translation="MALVTTKQILLDAQEGHYAVGAFNVENMEMVMAVIEAAEELKSP
                     VILQTTPSTIKYAGLDYYLANVKVASEKASVPVAMHLDHGSSFGLAMQALRVGYTSIM
                     IDGSHESYEDNISISKSVVDACMPSDIPVEAELGKVGGKEDDLDGGDGGAYTDPLEAK
                     EFVERTGVSSLAVAIGTAHGLYKGEPKLDLDRLSEIREVVSVPLVLHGGSGIPDEVIK
                     ESIKRGICKVNYATELRIAYSNGVKDVLNSDPEVIDPKKYGKKGLESVKDFVKSRMEV
                     CGCVGKAIGTVKC"
     gene            complement(11115..13031)
                     /locus_tag="PC466_000756"
     CDS             complement(11115..13031)
                     /locus_tag="PC466_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIABC"
                     /protein_id="HDF2768178.1"
                     /translation="MGKKMILGVTGCPTGIAHTFMAEEALKNSARELGCDIKVETNGA
                     IGVENKLTAKDIEMADAIIVACDKNVDMDRFNGKPVIEVPVKEGIHKANELIQRCIDG
                     KVAIRKGNLSSSKIAEEGNLSFGQKLYKDLMNGVSHMLPLVVAGGVLTAISFLWGIYS
                     FDPNSEQYNQIAATLKSVGGYSMNLMVPVLAAFIAQSISGRAGMLAGLVGGMISFDTG
                     SGFLGGIISGFLAGYLVKLFVHLLRKLPRQLEGLKSIFIIPIVSVGLVGVAMLLLGGP
                     CSALNNAMMNFLSGLQNSSPIILGIVIGCMSAFDMGGPVNKAAYVTGTMLLGQGNYLF
                     MAGVSAACITPPLVIAIASTLFKNRFTEEDRAAGLINYILGSTHITEGAIPFAAKNPL
                     KVLPVLMIASSISSILTYIMKIEVPAPHGGFLVLGLVNKPLLWVGCIFVGSLVGAVLY
                     MMVTPKVVNEKNTIENTNATKDGHKNESAESENVSNNISLYSEETVILDVKGKNKTDV
                     IDEMIGILDKSGVLLDKKKFKEEILKREEISSTGFGMGIAIPHAKTDAVKVPRVAVGV
                     SKEGFDFESEDGSLAHIIFMISATDNGDNLHLKTLSQLSSKLMNEEFLNELLNSKTSR
                     EIVSKLNNEEIKSV"
     gene            complement(13034..13954)
                     /locus_tag="PC466_000757"
     CDS             complement(13034..13954)
                     /locus_tag="PC466_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase family hexose kinase"
                     /protein_id="HDF2768179.1"
                     /translation="MIYTLTTNPAIDMNISTNGIKRKLVNRTSNAVYSPNGKGLNVTF
                     VLGHYGIESKILGFFGGFSGKYIVEESEKRGFDVLPTWVEDTTRINIFLNDGSDEFKF
                     VNSGSYVNEKQKLDMLDKIQSLADISYLSISGSLPPGIDDNYYEDIFKICKNKSIKTI
                     LDISSPKLKELLQYNPYLIKPNDEEIKDIFGIIVRDEEDIKDVLKLLHLKGAQNILLT
                     LGEKGSYFYNGKSIYYASAQPVTVVSSACAGDSALAAFLSIWLENPEHIEEALKRSAA
                     TGASVAESNGIGNLENVEDYIKNIRVRKVV"
     gene            complement(14056..14808)
                     /locus_tag="PC466_000758"
     CDS             complement(14056..14808)
                     /locus_tag="PC466_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDF2768180.1"
                     /translation="MIIELNKSNSENLTKTELEIIKFINENESILPELSIVEIAHETY
                     SSPATVSRAIRKCGLNGFNELRYRLTVKDENDDIQNMGDIINKSFIEAQRVIEQISLT
                     TLINIIKTINKSSKIYILARGLTEYVAKEFSLKLQLLDFNVVFINDPNIMKIKSKSIK
                     KDELIIIFSLNGNTIELVESAQNANLVGAKVITCCCSESAKLIKYSDLYIVGYKHEHI
                     SISEYEVSSRLPLYIISRIIIDYMVRYNNSEN"
     gene            complement(15105..15722)
                     /locus_tag="PC466_000759"
     CDS             complement(15105..15722)
                     /locus_tag="PC466_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768181.1"
                     /translation="MNVIKKFIFVILIINILGCGISLILQSSLGSDAITLLNEGIHIK
                     LGISYTIAGLIYNGTLLLIALLLNKKSLGLGSCVYVLVAGIFIDLYIYLLLDFNISSL
                     GIIIRIMSFIIGHILMCSGFAMLIKFDIGMSPLDAILIYIEGKFKYPYKVLKTIADLI
                     FLILGVYLGGNLGFGTIFSILCTGTTISIVSKMISVNKKRYYSSI"
     gene            complement(15810..17267)
                     /locus_tag="PC466_000760"
     CDS             complement(15810..17267)
                     /locus_tag="PC466_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HDF2768182.1"
                     /translation="MIKLSKFPKDFLWGGAVAANQLEGAWNEGGKGWCLADVHMYDKD
                     RDISKHYESDMTVDKIKFAMKDNNGYYPKRNGIDFYHTYKEDLKLLKELGLKCFRFSI
                     NWARIFPNGDDLEPNEEGLKFYDNLINEVIDNGMEPIVTLLHYETPLNLVLKYKGWSN
                     RKVVDFFVRYAELILNRYKDKVKYWIVINQINLMYHESFNSVAFCVDQVDDVEEAKYQ
                     AIHHQFMATALTKKLGKEINSDMMIGMMMADCTSYPEDCDPENVVFALKRNRIQYFFT
                     DVSFRGEYPAYIKRFFKENNINIVMEEGDDKVLKENTMDFLALSYYYSTTVSASKNTM
                     NPIDNVKNQYLKANPWGWAIDPKGLYNTLSQYYDRYQKPIMIAENGFGMHDKFEDGKV
                     HDSYRIDYLGKHIEQIGEAIADGTEILAYCMWSPIDIVSCSSQEMEKRYGFIYVDIDN
                     NGNGSKERYKKDSFYWYKNVIRTNGEELKEKVDSF"
     gene            complement(17289..17642)
                     /locus_tag="PC466_000761"
     CDS             complement(17289..17642)
                     /locus_tag="PC466_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HDF2768183.1"
                     /translation="MTTEEHVIDEELVEVAMQIILRAGEARTEIKHALNDLERFDYKN
                     ADLKLAKAKEFMTEAHRAQTNIIQGEASGEKRAHSLLFAHAQDTLMTIFSELNITMSL
                     VGIVKSIEYKVNNSK"
     gene            complement(17671..18918)
                     /locus_tag="PC466_000762"
     CDS             complement(17671..18918)
                     /locus_tag="PC466_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF2768184.1"
                     /translation="MGRLFMNKFIDLLSEKFTPVVNKITKNIWVQSVQSTIMKVLPMV
                     FVGSLVTIVSVLKNYISFLPDLSPINQYTFGLLGLFIAFLLPMEIMKNKKFESMSVVA
                     GLAGAGLMLMMIRPEITNEGAIFNFNRFGGEGMLVALVAGLFSGLIMSLFGSFSFFGE
                     DSALPDFVSKWFDSMLPIAVIMFIGWGLIYGLNFDMFEIIVRIFKPVSDIAQTLPGFV
                     LLNFLVVFLYSLGISGWVLSPITYAIQLSAIAANAAAVASGGLATNIYTYEVVQTGWI
                     TLGGWGATLPLVLMMCLSRAGRIKAIGRACIVPSIMNINEPVMFGAPVAWNPFLMLPM
                     WIGTVVISITTYLSMSMGFVTIPSKVFNLWYLPFGISTFMVNQDVRGLIVLAINIVLL
                     FMIWYPFFKAYEKEELKLESQEA"
     gene            complement(18926..19243)
                     /locus_tag="PC466_000763"
     CDS             complement(18926..19243)
                     /locus_tag="PC466_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2768185.1"
                     /translation="MKNIKVLLACGSGASTGFMATSMRKSAKKKGIEADIKARSESEI
                     DKYLPEIDCLLLGPHLDYMKDEIQKKADEYNVPVACISKTAYGRLDGVKALEEALELI
                     LNK"
     gene            19491..21404
                     /locus_tag="PC466_000764"
     CDS             19491..21404
                     /locus_tag="PC466_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2768186.1"
                     /translation="MKTSKKELFLNFIKTQHDWIDSSTLANYLNVSTRSIRKYVNEIN
                     STGEFILSSKKGYKVNLNNNCQTKVDSSENISPDNRLNLILKELIVNSNGINIFDLSE
                     ELFVSPATIEGDIVKANKFIGSYNLKIKQSKFLLKLIGNESAKRKLMSSIIFKETGSD
                     FLSLFDVQKIYQEYNLTKLKENIIYILKKYNLFINEYAINNILLHLMITIDRIKKNNY
                     IESVEVVNYIDNNNDISISRDISNFLESEYNLTLTSAELYYLVFQLTNKTTVLNYHEM
                     DTKSLPNYIDEHFVKLTKKIIKNVYDLYFIDLSDDEFVVKFTLHVKNLISRAKNNQVL
                     RNQIPQKLKDSYPLIYDISVYICNQIQILENIEIDEDEISYISLHVGSFFDRQKLLED
                     KILCALITPNYYDLQFKIVRDLEKRFNESIEIIQIFSDTHNLDFDNKVDMVITTLPIS
                     DRCPIPFVYVNPYLNRKDYDNIQSKFIQIKDRKNILTVQNHLEMYFSESLFMKNIYLD
                     SAKDYIKFMGNILYKNKYVKPNYIDDVLIREKMSSTAFNNNVAIPHSMKMDALKTGVC
                     LIVNDKPVKWGEEKVQIIAMIPINEKEKEKFNYIFESFIEILSEWNNVKELTKADNYS
                     SFMNRIAYLIQNI"
     gene            complement(21527..22681)
                     /locus_tag="PC466_000765"
     CDS             complement(21527..22681)
                     /locus_tag="PC466_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HDF2768187.1"
                     /translation="MKILISIDSLKGSLSSIEAGNAIKKGILKVKEDAQVKILPLADG
                     GEGTVDALVQGMNGKKETIEVTGPIAKKVDATYGLLKNTSTAIIEIAQASGLTLVPTE
                     LRNPLYTTTYGVGEIIKEAINKGYRNFIVGIGGSATNDAGIGMLQALGFEFYDENNKL
                     VGLGGKVLNEIRHIKIENRLKELDECKFKIACDVNNPLFGKNGAAYIYGSQKGATSEI
                     IEELDNGLRNFSKVVKNYLSKDVANVEGAGAAGGLGFAFLAFLNSKLESGIKIILEEI
                     KLEEELKDADFVITGEGRLDNQTAMGKAPIGVAKLAKKYGVKVIGLAGATTEDAVKCN
                     EEGIDAYFSIVNRAMTIEEAMDKATASENMTATTTQIFNLITSIQQSKNM"
     gene            complement(22963..25578)
                     /gene="mngB"
                     /locus_tag="PC466_000766"
     CDS             complement(22963..25578)
                     /gene="mngB"
                     /locus_tag="PC466_000766"
                     /EC_number="3.2.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosylglycerate hydrolase"
                     /protein_id="HDF2768188.1"
                     /translation="MKKNVHIVPHMHWDREWYFSTEESRILLVNNMEEIMDMLENNHN
                     YPYYVMDGQTAILEDYLAVKPECKERIKKLVQEGRLIIGPWYTQTDEMVVGGESILRN
                     LLYGIKDCDEFGEYMKIGYLPDSFGQSAQMPQILNGFDIKYSMFWRGCSERKGTNKTE
                     FNWKSDDGSSVLVQILPLGYAIGKYLPMNEDELRTRMDKYLPVLDKGATTDHIILPNG
                     HDQMPIQKNIFEVIYKLKECYPERKFFLSRYENIFKELEKNKDIDTIKGEFLDGKYMR
                     VHRSIFSTRMDIKSANARIESKITNILEPLASIAYSLGFEYHHGLIELIWKEIMKNHA
                     HDSIGCCCSDKVHQEIMNRFFLAEEKVDQLITFYKRRIVDAMSCEMALDKLVAFNLMP
                     YNRNEIVNAQVITKMKAFEIFDKDNNKLDFEVVHKEVIDAGLIDRQIVHYGNYDSFMV
                     YTINFKDKIPAMGYKAYMIKEVEHMLEKAYEVCDMVDNDFYTIQVNENGTLKISDKKL
                     NKTFENVLLMENGGDEGDEYDFSPLPNEKLIFNDNIVANSTIKKNRFNNEIKINYRLK
                     VPKDIQARKNNRADSFIDFDIVINVPNDKAIINVVFNINNQARDCRVRTYIPTNIASK
                     FSVSDNQFGHIKRSVYDDAMEVWQQEEWSERPDSIYPMLTFVGLSDKEHGVAVLTNST
                     REFEIVGKKFDTIAITLFRSVGFLGKEEMARRPGRPSGIKLPTPDSQMIGDIKIDLAI
                     VTHEKSTLEANVANMAKEYLTKIQTYNKIPYNAMKLNQSEIEVDYSYSLLKETNKDLV
                     LSVVKKAEKEEALVVRFYNSKEETKSANVVFNKNIKTAKWTNLNEKELESISIDNNSV
                     NVECLMNQVKTILVK"
     gene            complement(25722..27647)
                     /gene="mngA"
                     /locus_tag="PC466_000767"
     CDS             complement(25722..27647)
                     /gene="mngA"
                     /locus_tag="PC466_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS 2-O-a-mannosyl-D-glycerate transporter
                     subunit IIABC"
                     /protein_id="HDF2768189.1"
                     /translation="MEFKKITNENLVFLKQKIKTKEDAIKFLARKLYDEGKLTSYEEY
                     LEAVMYRETLSPTGFERGLAIPHGKSKSVKEAAFAAMTLETPIENWESVDSNNKVELI
                     FLIAVPESEGGNTHIQILSELVTRLSNEDYMNMLLNSKTKKELFNNLDIKEKKEQIKE
                     EIRIQNESKKIVLAITACPAGIAHTYMSAEALIKAGKEIGVDVYVEKQGANGMVDPHT
                     PDIIKKADAIIYATDVAPKNTERFEHLPNIKTSVAAPLKRAKEIIYEALEVAQKQGKG
                     DYIEKSSDISYCEKSSWKKDVKSAILTGVSHIIPLIVAGGMILAFAVLASQAFGLQEL
                     YNQEGSWLWQLRKLSGGMLGTLMVPVLSAYMSYSLAEKPGLGPGFAAGLAADLIGSGF
                     LGGMLGGLLAGYIVKFLKKNIPAKGTLAGFVSFWVYPVVGSLVVGLLMLFVIGKPVAA
                     LNNGLINWLNGMTGINAILLGAIIGAMVSFDLGGPINKAAYTFAIGAIASGNFIPYAI
                     FASVKMVSAFGVTIATVLGRDLFSESEKEIGKQTWILGLAGITEGAIPFMIEDPIHVI
                     PSLVAGSAITGSIVAFFNIGLQVPGAGIFSLALLEGSMSGFIIASIWFFAAVLGAIIS
                     AILLIITRKQKNQRKIH"
     gene            complement(27777..28502)
                     /locus_tag="PC466_000768"
     CDS             complement(27777..28502)
                     /locus_tag="PC466_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDF2768190.1"
                     /translation="MEFYERAKKYEYKFTDTEDMIIEYMRKNKEEIVKLSIQSLADKF
                     FTVPNTIVRLCKKMEYDGFSQLKNNLKEELKNEDKEPKNGFESDIKKTLELIDYEKIN
                     KVADIIQKSRSIIVYGIGQNIPLCEILVKEIRGGHDNITYYSQRHEVLHDIGKLGEQD
                     MFFALSLSGETKEVIEAAKTAVNKGCKVVALTHICENQLQQIADISLYCYSTIKQVNG
                     YNISDKVPIMMIMRAIIEQYWLR"
     gene            complement(28765..29544)
                     /locus_tag="PC466_000769"
     CDS             complement(28765..29544)
                     /locus_tag="PC466_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ChbG/HpnK family deacetylase"
                     /protein_id="HDF2768191.1"
                     /translation="MHKMKKLVVRADDIGYSEGVTLGIISSYKNGIVTSAGIMVNMPF
                     SRQAIEMVKNDDVCFGLHVNLVIGEPCCKEHIKIKNLLDEGGKFVSSKIRRTQLLTGK
                     EVFNYEEVYEEVCAQIETYKLYMSKLPEYIDIHGIEEDVSISAMCDAAKEYGIPSCPY
                     YLDSCISMPSKYPQNDFYKLNKSFVKLFEEKYINLDKDITLMVTHPGFIDYSLIKSSS
                     LIQERVYEHAMLCDKEVKMWLKRNNIELVDFKDIFKSNNYI"
     gene            complement(29537..30964)
                     /locus_tag="PC466_000770"
     CDS             complement(29537..30964)
                     /locus_tag="PC466_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDF2768192.1"
                     /translation="MMQQLSLLGKTMLVPIAVMPAAGILGLLFGPNMLNVPAISNISN
                     IVFSNVDYLFLLGAVSAYSKSKDKTSVMVAAVVAYMIFKSNLELLNDTLNAGVFGGII
                     VGACIAWTYNKTYKVKVPAFLSFFAGEKCVITLSPVVALILSYIFSLLWIYPQAAMNQ
                     FGFWLGGAGAIGIFLFLFCNRALIPTGLHQVLNAYILFEMGEYTTSTGEVIRGEIPRF
                     MAGDPNAGFFWTGFYIIMMFSIPAISYAIYKTAQDKKKQEVKGAMTAGALTSFMATVT
                     EPIEFSFLFASPKLYIIHSFYSGLGGVVLYLLGARLGSFNGASIIDYVLSFSYGDKAW
                     LVIPVGVVFFVLYYVTFKYIIIKDNVQTPGHEVEIEIGDKVSEKEKNLKLSHGNFSYM
                     AKQIIKNCGGYENIVTLNNCMTRLRLEVKDATILNDDNIKKTGAKGVIKLSNTSVQII
                     IGTDVVKVKDEMEMQLDELRKQADA"
     gene            31355..32077
                     /locus_tag="PC466_000771"
     CDS             31355..32077
                     /locus_tag="PC466_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2768193.1"
                     /translation="MAKNKFSEIYEVLKEEILDGKYTSNMMLPTELQLIERFSCSRNT
                     VRRAISQLNTEGYVQSIKGKGVVVLENSCSNDFFLNMHNFKGVESIVEDKKVNTATSV
                     LHFSKILIDNKLSKKTGFKVGSEVYYLHRLRYIDNIPKILDINYFLCSIVKDLDVSIA
                     QGSIYKYIEECIGTKIVSSRKIFKIEKATELELKTLPLNDYNCVGVIKNSVYTDDGKL
                     FEYTESKHTPETFVFMDVTQRY"
     gene            32274..33941
                     /locus_tag="PC466_000772"
     CDS             32274..33941
                     /locus_tag="PC466_000772"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HDF2768194.1"
                     /translation="MKNWWKKATVYQIYPKSFKDSNNDGIGDINGIIEKLDYLYSLGV
                     DLLWLTPMYVSPQRDNGYDIEDYYNIDPKYGTMSDFEKLLKEAHKRDIKIMMDMVLNH
                     TSTEHKWFKESKKSKDNPYRDYYFWKDAKPDGSVPNNWISRFSGTAWKYDETTNQYYL
                     HLFEETQADLNLENEKVREECYKVLEFWADKGIDGFRLDVVNLLSKTPGLPDDPITGP
                     KGDGRTHYADGPRIHEYLHNMNQKVFKPKNIVTVGEMSSTTPEECINYTRENREELSM
                     VFSFHHMKTDYKGGAKWTNEMFSLDKLKKAQSDFQYKMYEGKGWNALFYSNHDQPRAL
                     SRFGDDRFFRQESAKMLAITLFGLQGTTYIYQGEEIGMTNAYFTKIDEYDDAESKNAY
                     YHMIKSGIDEKEALLILQQKSRDNARTPMQWDNTIYKGFSNHKPWLKVNNDNISVENE
                     LNDSRSVFYTYQRLIKYRKQYDIFTEGTYRLLDENHKNLFVYEREYKNQNLLVISNFT
                     HDNVVYKLPETYLNKLNYTILETNYTRDIIENKMEIKPYESIMIYYK"
     gene            complement(34037..35356)
                     /locus_tag="PC466_000773"
     CDS             complement(34037..35356)
                     /locus_tag="PC466_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDF2768195.1"
                     /translation="MEKGIKLGFWSIVLLGINAIIGSGIFGLPGDAYTDIGPASILVL
                     VFCMLLAVSIALCFAEAGSWFDTDGGPYLYAKEAFGDFVGFEVGFMKWIVSMIAWATM
                     ANFFAVTLSSVWPQAAEPLIKNIIIGILVVGLGIINFMGMKQSKHLNNIMTIGKLLPI
                     VLFIAVGLFFIKGSNFTPFVIIQKGQSASSAFVAVSITLFYAFTGFESLAVAAKDMEN
                     PKKNVPKALVMVMFVVSVIYMLILGISIGVLGNGLAGSATPVADAAIKMLGPIGGYII
                     TIGTIVSVGGINIASSIFTPRSAAALVEQGLMPKSIRKTNKNGAPYIAIIVSVIGTLL
                     IAWSGSFTTLSQISVVSRFIQYIPTCLAVLILRKKYADKDVNFRIPGGAIIPIFAVII
                     SILLLIKAGIDEPMKIVWGLGGMIIVVPIYFYMTKVYSKKYNDVEVK"
     gene            complement(35397..36143)
                     /locus_tag="PC466_000774"
     CDS             complement(35397..36143)
                     /locus_tag="PC466_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HDF2768196.1"
                     /translation="MKKLVKKKYPIIGISGNLLIDEGGMFPGYERAYVNNDYIQSVVM
                     CKAIPYIVPIVYDDEIIKEQVSNIDALILSGGQDVNPLIWKEEPHNKLGAISPKRDSF
                     DMKLLKHALDMKKPVLGICRGEQIINVTEGGSLYQDLSLIEGAYIKHNQQHLSNVPTH
                     TVQIKEGTKLYEILGEKEVLVNSFHHLVVNKVAPGYIVSATSKDGLIEAIEKEGSEFV
                     IGIQWHPEMMTRDYDNMKKIFMAIVKEASK"
     gene            complement(36387..38396)
                     /locus_tag="PC466_000775"
     CDS             complement(36387..38396)
                     /locus_tag="PC466_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2768197.1"
                     /translation="MKTIAVVTDGLSKLECFLNKNLEMIFKDKVMIKNYYLNKITEKE
                     LIKDDIILVMIDDRVLKIKKYVEDVSKIITINRSIKQKDIYKLFSLPEEIDVLVVNDN
                     KHTVLETISNLYNIGINHLNFIPYNPNEEYRNIKIAITPGESSLVPKYIEEVIDLGHR
                     YIDSSTFIQIIAKLKLDDKEITERLIKYTDEIISLYSGINTKYKELTIKADELNSIIN
                     LSNLGMAMVSDKGNIIICNNSLRDILDIQSNIIGKNIDELENENIKKIFSLSKAHDEV
                     IKFNNKYLNVNKYNIESFGRVTGYYFCIQEITYIRKLEQNLSKKLREKGQVARYTFDD
                     IKTVSTKMERTKKLGMKIAESDYTILITGESGTGKELMAQSIHNASPRHSQSFIAINC
                     AAMPENLLESELFGYEEGAFTGALKGGKKGLFEQANNGTIFLDEIGDMPIYLQSKLLR
                     VLQENQVMRVGGENVIDIDVRVIAATNKNLLEMIKGDRFRADLYYRINVLPINIPPLR
                     ERKEDIEVMLKHFMKRKRAISQGVQDIINAYEWPGNIRELKNTAMYINIMSSEDVILI
                     NDLPHNLLNITEDFSKEISILKDRTSIEKVKLVMECLKNANNLNKNIGRNGIVNSINE
                     LGYSITEGEVRGILNMLKELDLIICESGRKGSELNRRGKNILNSI"
     gene            complement(38834..40267)
                     /locus_tag="PC466_000776"
     CDS             complement(38834..40267)
                     /locus_tag="PC466_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HDF2768198.1"
                     /translation="MVLRKDFLWGGATAANQCEGAWNLDGKGPSCSDMCTGGSQKVSK
                     RITRVIEKGTFYPSHEAIDFYHRYKEDIALFAEMGFKVFRFSIAWTRIFPTGMEKEPN
                     EAGLKFYENVIDECLKYNIEPLITISHYEIPFAITEKYNGWVSREVIDLYMNYCETIF
                     KRYKGKVKYWLTFNEINSATMPMGGYLSQGILNEGTTDFINQVDIPQLRFQGLHHQFV
                     ASAKAVKLAHEIDSNYQVGCMQIFATMYPYTCNPDDAVKTQRDSRVMNYFCGDVQVRG
                     EYPTYMNRYFGENNIEIKMEKGDLEILKEGCVDFYTFSYYMSTCVSSDSKEDNTSGNI
                     LGGVKNPYLKSSEWGWQIDPEGLRYALNEIYDRYRIPMMVVENGLGAYDKKESNGVIN
                     DDYRIEYLKAHIEQMKEAVEDGVDLFGYTPWGCIDLVSASTGEMTKRYGFIYVDKYDD
                     GSGDLSRIKKKSFDWYKQVIESNGERL"
     gene            complement(40354..42270)
                     /locus_tag="PC466_000777"
     CDS             complement(40354..42270)
                     /locus_tag="PC466_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF2768199.1"
                     /translation="MRRYEQLSKEIIENVGGKDNISSLSHCITRLRFKLKDESIANDD
                     VLKKMDGIVTVMKSAGQYQVVIGNHVPDVYEVVCDLAGLGGDTIDNSDSDAPKGLLNK
                     FIDIISGVFQPILGVLCAAGMIKGFNAVFTALGLYGETDGAYIMLNAIGDAMFQYMPI
                     ILGYTAAKKFKLKPFIGMLIGAVLCYSGIQLDTLASIGQPLYNLFTGTIFESPVYITF
                     LGLPVIAMNYTSTVVPVIIIVLLAAKLEKVFAKIIPDVVKNFFVPMAVLLVSLPLGFM
                     VIGPIATYASNIVGNGFLALFNFSPILCGVLTGLLWQVLVIFGLHWGLVPIAMSNLMT
                     MGFDTILVGAFVPSFAQTSVVAAMYFKLKDKKIKELCIPAVISGICGVIEPAIYGITL
                     PRKTPFIYSCVGGAVAGAVMGIMNVKSYVMGGLGIFGIPNYINPTTGDMKGVYATIIA
                     IIVAIVVGFVLTLFFWKDDSIVEISKDNNGQGVVEKNKREVVYSPIKGEVKALEQIQD
                     AAFSTGILGKGVAITPKEGKVVAPFDGTIMTLFPTKHAIGIISDNGCELLIHIGLNTI
                     QLEGKHFKSFVNQGDKIKKGQTLITFDIESISKEGYCLETPVVVTNYSDYVDIIENTQ
                     KHVNNSQELITVLA"
     gene            complement(42344..43204)
                     /locus_tag="PC466_000778"
     CDS             complement(42344..43204)
                     /locus_tag="PC466_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDF2768200.1"
                     /translation="MIIEKILNNNVIITTDENHKEIVVMGRGLAYKKRTGEHISKDKI
                     DKIFKLSDPNISDKFKELIADIPIRYMELSDEIILYAKEKLGKRLNDSIYISLTDHMY
                     TAIERAREGVSVKNVLLWDIKRFYKSEFKIGLEALDYIEKKFEIRLSEDEAGFIALHI
                     VNAQMDQSIKTIYEITQIIQEISNMVKYHYRIVFDEDSVYYHRFITHLKYFAERIVSN
                     NLHENNEDDLLNVIKVKYKNAYKCIEKLDEFIHKKYNYDLTDEEKLYLTIHVERVVSK
                     SIKSDINPNN"
     gene            complement(43555..44742)
                     /locus_tag="PC466_000779"
     CDS             complement(43555..44742)
                     /locus_tag="PC466_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HDF2768201.1"
                     /translation="MIESIKKRAYEIENELGKEIEEVCNFIFNNPELGEEEYISSKYL
                     VEKMKEYGFDTVYPYCNMETAFRAELGDNDGPTIAFLAEYDALPGYGDNKEPAHACGH
                     NWIAASTLGACIVLSKLKENFKGKIVLIGTPAEETTGGKCDLVKAGAFDDVDVSYQMH
                     IEAFNNINCKALAIDSLEFSFEGVSAHAASHPHMGVNALDAVQLTFAGINALRQHVKS
                     DVRIHGIVSNGGEAPNIVPEKAACKFFVRAAERSYLDEVTKKVINCAKGAELMTGAKL
                     SYRYFENSFDNIINNKVLQKITKNNLIESGITDILEGKDGPVGSTDIGNVSQVCPTMY
                     TEIALDISPMVYVHEKEFLNYANSEEAYDKLHKAVKAMVGCALEIYLEDGLLDEIKKN
                     HLN"
     gene            complement(44756..46147)
                     /locus_tag="PC466_000780"
     CDS             complement(44756..46147)
                     /locus_tag="PC466_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HDF2768202.1"
                     /translation="MSSLKKKKFTMPQTLTIIFSLIVLMAILTWIVPSGNFERVDIDG
                     RSVVVAGTYEKAPSNPQGITDVFTAPINGFIDAAEVVGFVLIVGGAFGIVNKTGAIEA
                     VIAHTVNKMKKFQFLIIPISMILFGLGGTTFGMSEETLPFYMIFIPLMTSMGYDSLTA
                     VATVFIGATAGFGAATTNPFSVGIAQALSQIVPGSGIEFRVVMFIIYMAISIGFVMMY
                     ANKVKKDPKKSLVHDISLNQESMVNSDTNIKEFTKREAMVIAIFTIGMAIMIYGVLRL
                     EWYITEIAMIFTAIGIISGIASGLKQDEIVNSFISGAGDLITAGLCIAFARGIVIIAE
                     NGFIIDTILNSAANLLNGLPKTIFINLTFLIEGLIAFLIPSASGLASLTIPVLAPLGD
                     LVDVSRQMIVTAYQFGIGVTNLITPTSGVLMGALAVANIPWSKWVRFVIPLMVVLTIL
                     VMVFLTIGLYLGF"
     gene            complement(46742..48442)
                     /locus_tag="PC466_000781"
     CDS             complement(46742..48442)
                     /locus_tag="PC466_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDF2768203.1"
                     /translation="MHYIAWHFNKNGGNNTMKDKLQVLSGAMMIPVILLVVAGVFIGL
                     GSAFANMENVSALGLSGLIKEGSFINVFFKVINDLGFMVMRYLPIFFVTGIAFGLSKK
                     EKGWGALGGIVLFIGMHTVISTLLASNGINSDTVTAEAFMASGLGEAEAYSRSSLYGS
                     FLGIFSYDCSIFGAIIAGFVASAVHNKFVDIELPSALSFFSGPRFSMIMMFIASIVLG
                     TAMYFIWPPVGLALSKLGNWIGSSGLLGTFTFGAMDKALLPFGIHHLIAFPIEYTRVG
                     GTMEVGGAIYEGVNNIRLAQMGDPDTLSYITRNFTTGRLLIHFAILPAAALAMYKLAD
                     NANKKKAISILIPAIVTAMLVGVTEPIEYTFLFVAPLLYFVAYVPLAGLTYVFTEMFN
                     VSIMGESFRNMFPNLLQPQKVDALPLLFLIPIFFIVTYIIFTWAIKKFDIKTPGRSSE
                     EVKLYSKKEYRERQSVDAGKTAYNNAVEEEVDDKDTKLVHSIIEGLGGSNNIKNVTNC
                     ATRLRVELNSIDGFYEDGFWVNELGASGVVKKKNSVQVIFGPRVITIASKLKAVLGVD
                     "
     gene            complement(48414..49817)
                     /locus_tag="PC466_000782"
     CDS             complement(48414..49817)
                     /locus_tag="PC466_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HDF2768204.1"
                     /translation="MIVNKELIIDYLKSNQENIIKDIRSLVEIPSIRDESTTDINQPF
                     GIEIRNAFDKLIQIAKDKDFVVKDFDGYAIHIEYGEGEEVVGVLNHIDVVPIYNKELW
                     KSKPFKVCQKDNYLYGRGVNDNKGPLIGILYALLFLRELNEKPKRKIRLIVGGAEETT
                     WECMEHYFSVNEQPKFAFSPDGNFPIVNGENGILYFNLRKKIDKDKFRNHNLVDIKSN
                     KEDGFVCDKIEAVFKTDDKKDLVESLAYYTEIEELEEGKVLVRYTGERALSRNPHRSY
                     NCAFSLAKDLEKIKKLNDKGVIIRDILNSYFTDDNHGKKLGIYKEDVDMGVSTICIMS
                     IFLEKNELNMKIDFRYPKGISWEFITNRINEIGKKENLIVDIYKDLKLLYVKPDSELI
                     NKLSSAYKQGFGKEAELFTKGAASYARVLKNGVAFGPTIEGDNPNSHQANENISIDTL
                     YKAIEVYIYALYSLAFQ"
     gene            complement(50081..50572)
                     /locus_tag="PC466_000783"
     CDS             complement(50081..50572)
                     /locus_tag="PC466_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF2768205.1"
                     /translation="MFNIFKKKENKIEKIYSPFKGNLVNLEDVPDAVFAQKMMGDGVA
                     IIPNEGKLYSPVDGEIVNVFDTKHAIMIKSNDNTNILIHVGLETMSLEGKPFDVKVKA
                     GDKVKAKDLIMEVDLDFITSNDLNIITPVVIMDDADSVKRTVKDRIEPGNVDINSIIM
                     EVE"
     gene            complement(50598..51410)
                     /locus_tag="PC466_000784"
     CDS             complement(50598..51410)
                     /locus_tag="PC466_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDF2768206.1"
                     /translation="MRYKLICTDMDGTLMGKGFEVSEENIKALKEAMEKGIKVALVTG
                     RPYNAMKYFTSVLGDDIYIISTNGTYFKLMGYEYKKVLSKEAIKKIYTIGEKYNLNKH
                     FKGCKIVISNNEIGEEHPYRLINSKNKEEDRIEIIENASCETLLEKADNEILKCILFS
                     ENVDSLREAKEEFKKQEDLEVVSSGKINFEVMSKGTSKGIAVKKFCDILGIDSKEVIC
                     IGDNENDISMIKFAGLGIAMGNATDEVKSMADFVTDTNVNDGVAKALRKILS"
     gene            complement(51423..52574)
                     /locus_tag="PC466_000785"
     CDS             complement(51423..52574)
                     /locus_tag="PC466_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HDF2768207.1"
                     /translation="MINFYQPSRINFGQGTLSELPRIIGKYGKKCLLVTTPNVEPLDK
                     LYKRVTLNLIEKGIEVVHFDRVEPNPTVELINEGFELAKKESVDVVLAVGGGSSIDTA
                     KVLALTFGLEKIDWDYMFSTYTNPFKIYDKVSEKELPLIAVSTTSGTGSQVTQAAVIS
                     RGSEKNTIFHQNCFSKECIVDPELMLTLPERITASTAFDAFTHAFESYINPNANDFTE
                     IMSEKSMELVINYLPKVMEDKNNIEYRTKLAVADTLGGSSLANAGAAAPHPLSEIIGG
                     VTHIPHGEALAIVFPKFAEKFYKDNIEKFAKVARMLNQELEKVEDDEAAKTLGNEIES
                     FLKRVGLKTKMSEFNVTKEQLEQITSCPVLGFLPFGKKEDLVEILEKSY"
     gene            52844..53485
                     /locus_tag="PC466_000786"
     CDS             52844..53485
                     /locus_tag="PC466_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldolase"
                     /protein_id="HDF2768208.1"
                     /translation="MKYLIDSANLDEIQKCLKYGFKGITANPSMYLKEKVNFHEFIET
                     CTNLNPEILTAEVIGNNLYELINSCDKILNINKNTIIKINFSEVGLELINILNSKGVK
                     TACTLIFNVNQASLAINAGADYLFPFIGRNDENGNDGIKNLTEICNLISINGYNTKVV
                     AASIKNVFHLTQASLCGCDYAAVTYDLFKKASFNQLTVDGANTFERDWSKVNK"
     gene            53511..55055
                     /locus_tag="PC466_000787"
     CDS             53511..55055
                     /locus_tag="PC466_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDF2768209.1"
                     /translation="MNKRLLDIAELLLNSSDYITVDTIAEELKVSNKTIRNDLVILDE
                     WLLEFNLSLDKKTGSGVIILGNEDIKLKVIRDINDKSNCIYAYSPEDRKRYILSKLFI
                     KNSKFRIRDICNELHVSRATVHKDLVVIQNFLQNFKVTLVRKTNNGVYLEGKEKDIRK
                     AVFELATVNKSYTELKEILFSNSNECKDTPSTKIFKELFNYDFEKLSQITLHTLQVEK
                     SNLSDEYYINFLIHIAICIKRISIKRYINLSEGFFRELLEHEYFEKSKILCANLSEAF
                     DVEFIDEEVCYILLHIEGLLKSIKKTTTLEPLKNEEITEYNLSEAIAVHWGSILNLNL
                     KDDLILIKSLANHLKSVLHRINYGFTITNPILNDIKRTFPYTYKAAKESNTVIKQLMN
                     YEVNDDEIGYLALYLISAIDRSKSPLNTILICHCSDGVSNLLVQKLSFEFNQINIVKS
                     IPLSSISFTNFDDVDLILTTAPVDFEHNAELININALLSKNDISRLSTIIKKLYSEKN
                     KILSYK"
     gene            complement(55272..55898)
                     /locus_tag="PC466_000788"
     CDS             complement(55272..55898)
                     /locus_tag="PC466_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HDF2768210.1"
                     /translation="MKKEMIKDYLLITISAFLMALAVNFFFAEHTLAPGGITGLSVVL
                     STFLSMPVENISLGISMPLLVMGLLFLGKGFGIKTLYITLMGPLFLKVIPQTHITDNL
                     LVAGVIGGLLVGTAIGIAIIRGCSTGGTDLVAMLINKVIKFLKLPVILFMLDGFIIVA
                     SGIISKNFMISIYSLISLLLIIKTIGFVTTKFGKNTEEINNINNACAQ"
     gene            complement(56033..56749)
                     /locus_tag="PC466_000789"
     CDS             complement(56033..56749)
                     /locus_tag="PC466_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentose-5-phosphate 3-epimerase"
                     /protein_id="HDF2768211.1"
                     /translation="MKHIKIAAGLAHVNYGHISAVVKEAMDAGVDYVHSDAADMHDLK
                     NMQLMGGHQIIEAIRPVTDKPIECHIYTRDCDRLFIEKIAAAGCNLLIIPAEHFLGAP
                     LAYIINYCREFGMKVGLTIGCYTPLCFVDEAIYDIDRLQIVVHGVDETDGKDNWGWRK
                     SAVDLVKRARKMIDEKNPKCELAIDGGLRADNMEPLIECNPDVVILSSAIFKDKDGIT
                     AGVKNCRKAIDEAATKFGLE"
     gene            57164..58378
                     /locus_tag="PC466_000790"
     CDS             57164..58378
                     /locus_tag="PC466_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HDF2768212.1"
                     /translation="MRNCIIAQSGGPTAVINASAVGIYEKNLETKYFDKVYFGINGIE
                     GILNKNIIDSDSLNKDNVLNLKQTPSSGLGSCRYKLADYKINSYDYDRVINILDEYEI
                     DTLFYIGGNDSMDTVMKFSQYCKNTTCKIKFIGIPKTIDNDLLGTDNCPGFGSAAKLI
                     STLIMETYLDFSIYKNNGIFIVETMGRDTGWLAASSSLARLNDTPLVDLIYLPEIDFY
                     EDKFIEDVRKIFKEKNKAYIVASEGIRDKYGNFICEQKTSAHDKFGHSQLGGVSNYLK
                     NLIVSSSITTRVKTLELGVIQRCAMHLASDTDLKQAAEVGAYGIELSKKGYTGVMAII
                     NRTCNNPYKYEVSHTDISKIANKTKYFPKEWINEECNYITDEALNYLYPLIQGKPDIK
                     YKNGLPYFSIIY"
     gene            58997..>59221
                     /locus_tag="PC466_000791"
     CDS             58997..>59221
                     /locus_tag="PC466_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768213.1"
                     /translation="MMKIAVITTEFLKEFVDNSIKKLNINAEIEIYIYRDFSHVGDLY
                     LEIEDRFDGFAVSGPIPKKAITKKAGTIKKP"
BASE COUNT        19306 a        10560 c         6400 g        22955 t
ORIGIN      
        1 agaggtgcta ttttattttt aatataatta atattctatt acgcaaaaaa tgcatatatt
       61 tcattatttt atggaaaata ttacttcatt taactctata tcaaactcat taagtaaaaa
      121 tctaattata tttaatttag cctctgtatt taaatttgtt tctaaatata tattttctga
      181 tattttaata ccttttctta atttatatac atctctagac ttaatattat ctataaaatc
      241 tcttttataa gtcttgtcta caatactgtt aaaccttaca gaatccaaat catataaagt
      301 aagagcaact tgttcataaa attctgtcca atttttagcc ttatatgact ctcctaatat
      361 actaaatgat actatacttt catttgtaaa attaacatca tcatcctcta acgtaaatat
      421 attttcactg ttacttggag gttcatatgt aacacttgga tatttccaaa tttctacagc
      481 tctatctagt aatatcttag ttctattttt tatttcttct tcattccatt tatctataga
      541 tgaaatatat ttatttagat aaagcctact atctttaaat ccatcttcca tttctttctt
      601 ttcttcaaat gttttattac ttagttttga attatatcct gtcaaagtta aatttccaat
      661 tgtatgtaaa tatttatcat gtatctcctt atagttatct cctagtgatt ccttccattt
      721 atttgttaat gtctgtggca ttatatgctc tatatttagc atattattat tgattaaatt
      781 ttctaaatca acaatttctt tattattata attctctaac ctctcaagta tatataactt
      841 attctttgac ttagtattat atatatcttt agtttcaaaa gcatttgaaa attcactgtc
      901 agtaggaaat ctttgagatg atttcttatt tataaaaata tatcttaata tattagaata
      961 gttttcttta taatcactaa attttttaat ttcccttcct aagttcataa atactttatt
     1021 cagtgcattc ggaggtacat cacatactat tcttcttaat ataaaacatt ctactaaatt
     1081 aagggattct acaagtactt ttttatttat tataccttca ttataatcat taaataattc
     1141 taatataaac ggatatgata caaatatttc aagtttgttt atccttttca aaactttgtt
     1201 tacatcatta tcatcagtac atgaataaga tatctctcta taatagttag aaaatttaag
     1261 taaatctttt aataaaattt ctatatctat accattatct gatacatacc ttttaaaact
     1321 aaaatatact ttatttttat tcggtatact tctctccttt atagtcaaat agtctcttat
     1381 aaagctactt acgttgctac ttgtattttt ttcaatttta taccaataat tattataaaa
     1441 ttcctcttgt aacttagagc ttctacccat taacacaaag tttcttactc tatcagcttc
     1501 acttaaatct aagccagttg aatttagact ttcaaagatt aattgagggt catcttcacc
     1561 attttttaac tctatttcta ctatagttaa tttctgtata gcatcaaaca aatcatctat
     1621 tgatatatta tcttctttta ttctattata aaaatataaa taatttgaaa ctatattaga
     1681 atttctatct gtattcattt cttcttcaaa tagttcatag taagcttttc tatcttctgc
     1741 tattggtttt aactttattt ttccatcttt atctcttgag tgcttgttta taagataaca
     1801 ctccttaatc tgttcttctg ttgtaataat tccttttgat tctccaaact cttttattat
     1861 ttgacacatg gcaatcaata atattgacac agtagtcact ctttgttgtc catctattat
     1921 taaatattct tttcccatac tatatataga tacaactgac cctaagaaat gagttctaaa
     1981 tccagaatct attatatcct ctaaatcatc aaacaatctt ttacattgtt ctttcttcca
     2041 gttataattt ctttgatata caggcactac aaaacttttg tttgacccct ctaaataact
     2101 aagaaattca atttctcctg ctttcatatt aactccccct ataagttaaa taaattccat
     2161 tcataactcc atgtatctat atattatatc aaaattttga ctcataaatg tatatgaaag
     2221 ccttattata taccttttta tacctatttt tattttatta aagtaaatac atgattattc
     2281 tataaaatat acaaatactt aattttaaaa attattattt aatcttcttc atgagtaatt
     2341 catagttatt tatcaattaa aaagagatat tgcataatta ttcaatacct ctctttgtat
     2401 atttacatta tccatatcta gttatctatt tcaacccaat attagactac ctactaataa
     2461 atttattctc tacataatta acaataattt tgcactaaat aacatcatta gcctatctct
     2521 gatgcatttt ctttaatttt atttatagtt ttaatcaatt tatttctctc ttcaatatga
     2581 ttttcaaata aatcaattat acttccaaca gttctaaatg ggtcttccat caacactttg
     2641 ttatcctcta taaatccatt cttgactaca taatcgacta taagtttaac aaaatgtatt
     2701 tgcttagtat taaaactctt attatttaaa aactctgaaa aagcttcatt tgcagcttct
     2761 ctatccaatc ccactagttt tctcactaat tgacttactg gagtatctcc aaactccttt
     2821 ttataatcat cacaattacc taactgcttt aagagtattt cctccaacgt ttcaacatct
     2881 tgctttgtta tctttttatt atttcttaat ttaaatattg ctaattcatc tttatggcta
     2941 tttaaataat actctacctt ctttttataa ttcttaagat tgtttgcatt atatacagaa
     3001 tcatttctat cttctgctac aatcatatct tcaaaacttg tataatatat cttttgacta
     3061 gacttttcaa gatacttaat aagctctctt aatgatatac gtacttcttc tacctcaaat
     3121 atatctgaat cttcccaaaa atcctctgtc attgcttttt caatagtata tttttgttgc
     3181 tggatctgtg gtatagtccc aagtttcgaa agtttttctg ctgtaaccat tacatgcctt
     3241 atccctttac ttgcattatt attttgtaag tatgcaagtt gtatattata cataactaca
     3301 tcaaatcttt tagccaattc atcatcacta tatgaagtta tgagtggtga tatatattct
     3361 cttatctcat tttgtgctac tgctccaata ttgctccaaa cattttcatt tttatactta
     3421 tgtacataac ttaaattcat cctaactata taactatcct catttaaagc ttttacagaa
     3481 gttataagtt cttctaacaa ttcttttcta agttctgcat acttaccttc tatatattta
     3541 atatcttgaa gttctttaac catacttacc tttatattaa ataatttttc agtaagtgtt
     3601 tctgctttat ttccctcaaa tcctttagga ttaaatttaa aaaattcaaa attattacaa
     3661 aaatcaaata ttaagaatct ttccttatcc atatcaacac ctaataaatc tggacataat
     3721 ctagttcctc tacctatcat ttgccaaaac ttagtcttac ttctcacttt cttgaaaaaa
     3781 acaagattta ggatttcagg tatgtcaatt cctgtatcaa gcatgtctac tgaaactgct
     3841 atttgaggta atttattctt atcagaaaaa tcatctatta tagaatctac ataatttata
     3901 ctatagtcaa ctgcttttac aaagttccca ccatactttg gatacagttt attaaatctt
     3961 tcaactattg ccctagcatg ctttgtattc tttgcaaaaa ttatagtctt accaatcttt
     4021 tcttctcctt ctattttcaa cccctctgtc attagcttat ttaaaactaa atctattgtg
     4081 tcagaattaa atagccactc atttactgca ttattcccta tttcgtctcc aatactctca
     4141 tcatcattaa atgtattttc atattcttcc ttctcttcat cagaaagctc atcatactta
     4201 attccatctt ccataatctt agtcttaaac tcaatactag tataatctac taaatatcca
     4261 tcctcgactg ctttattata ctcataagca tatgtaggta ctccattttc catgtcaaaa
     4321 actgaataag tatttttatc tatctcatcc tttggtgtag cagtaagacc cattaagtaa
     4381 gaatcaaaat aatcaaagat tgacttatac tttttataaa tacttctatg cgattcatct
     4441 attataatta aatcaaaatg accaggtgta aacaatctct ttccatcctt agacttcgta
     4501 tcatcaattg cattcatcat tgttggatat gtagaaaata tcatcctagc atcttctggg
     4561 ctgtctttgc tatccaataa attacataac gccaagttag gtaatagctt agtaaaactt
     4621 tttttagctt gctttaccaa tgcttttcta tctgctagaa ataatatatt tttaatccaa
     4681 ttatgtcttg aaagtacatc aactatagat atagcaattc ttgtttttcc tgtaccagta
     4741 gcacatacca aaagagtttt gcgttgctta ttttcaagag cctcacatac agccctaata
     4801 gcttcttttt gataatatct attggatatt tcatcattta ttgttacaga acttaaagac
     4861 ttcttactct ttcttctatc tatcataagt tgtaattctg attttttata aaatccataa
     4921 acttttctat ctgaatagtc atcccaaata tacatatcaa aaccattcgt caaaaatatt
     4981 actggtcttt gactatatct cttttccaaa caatctgcat ataatttagc ttgttgttga
     5041 ccaattttcg ggtctttgct cgttcttttc gcctcaacta ctgctaatgg cttaccattt
     5101 tcaccataaa gaacataatc tacatatcct acaccacttt cattaggcat accttgtact
     5161 tctatttcct cccctatatc ttttccaaat tcccaacctg caagctttaa ttctatattt
     5221 atatatcttt ttcttgtctc aaattcgttt acttcgtcta tcttgaaatc gtagtttaca
     5281 gtattaactt ttctcttttc agttagtgac tttcttaatt tctcattttc ttttattact
     5341 tcttcaagct ttttatcttt tgaacttaat ctctcataaa gatttttaag ctcgtctggt
     5401 ctcgtccttt tctcttcccc atgaagtaat aaatcttcat taaagtcttc tgctgtatat
     5461 tcatctgaat aacaatagtc tatccaacta acaaattgat gcaaattgtt aagtgaaagt
     5521 attgcttctc ctctctctat gttcgcacta gtatgtacag ataaattacc taatttaact
     5581 atatatttta ataaaggtaa catatcatag tctataagtt ctataaaact attattatga
     5641 atcaacgtac taagattatc ttgataaggc aatactaaat cactatcatt agcatatagc
     5701 cattttactg caagctctaa agctcttctt gttatagttg cacaagtaga tgggctaact
     5761 agtatacttt tttctgcttc taagcaagca gtattaaaac tattgaaatt tttcttcttt
     5821 tgtaaaaagt caaaattacc caaggctttt ctcccccttt tgtcccttag ttaaaataaa
     5881 tctctctaaa aactatttct tacagctgtt tcttatacta acaaatactt cttcattttc
     5941 tgtaaacaat tcgtacatat cttcaaactg tggtatatca tatccatgag aatcatcatt
     6001 tctcaatttt ctaagtgttt ctataactat agaagaattt ttaggtaata aattgtgata
     6061 ctcacaagct aaaaggtagt cataaaagtt tttagatttt atgtttaaat caattgattt
     6121 ataatacaac attgcttttg ttaattctaa aaatgagacc atatagcttt taaaaccttc
     6181 ttttatgtat ctagcccata actcaggcat ttcttcctta tcatataaga ttttgaagtt
     6241 ttgcaggtca tataagcaag aaccaaaatc cctatttact tcttctattg agttccaaga
     6301 taatttgttt ctaattacca tacatgtccc tccaatctaa gatatctatt acatcactgt
     6361 tttcaaaata gaatttattt atataatcct taaaatcttt agattcataa ataacttcac
     6421 cttctaaaat agctttttta agtgctattg tataattatc tgtaacaatt tttaggtcta
     6481 catcaatgtc taatatattt cttagagctt ctgtcttagt tgcaagttct gtaattggta
     6541 cttttttgat aggaatccaa gctatgtcta tatcgctttc tgatgtatgt ttatctgttc
     6601 cataactacc aaatattatg attgctagag tattttcttt tggaaataca tttattattg
     6661 agtttttaat ctcatttggt atatttctca tttaatcacc tcttgtttat taggtaatat
     6721 tgcttaattg aatttatatc cataatcttt taatctattt atacatattt ctctttcttc
     6781 atcagtaaac aactctttat acttttcttt taatactaat acttctaatg ataaatctaa
     6841 tctcttacac tcccatagcc ttgtaaatcc ttcagtagct ccttctttat tgattaattc
     6901 tttagcagct aataaggctc ctttgttatt tatcagttgt aaaaatcttg ttggcttata
     6961 gttacattgt aaatcagctt ctttatagat atttaccatg tcatgatata aatctagctc
     7021 tatttgattc atagatttta ttcccccatt ttaatacttg tatttcagtt gaacaattct
     7081 cctttaaaag ctttttgcat taatgagtta aagttatctt ctagttcttt taagctagtt
     7141 tccatttcaa acttcaaaga gtttacttgt ttaacgaagt tggcaaattg attttgaagt
     7201 ctaataggag gtacaataat atttattttt ctaacagcat ctttagttat cgtttttgtt
     7261 acagctcctc ttactttctc ttttatttta ctttccatat aggatgttag taaaaggtta
     7321 tataagaata tatgattcac tttatcttca ttaaatctaa gcataaattg attcatagct
     7381 aaagatactg gtttatttaa aaatggcatt aaataaactt tacctgcact acctatctta
     7441 tttattataa cctcaccacc aaacaccttt gatttttcaa gataattata tgcatgttca
     7501 tcgatatact taacaccttt ttcaaagtta ttattttcta aatctgtagt tcttaccatt
     7561 aaggcataac cttttgtatc taaaagagtt acattatctc ttaaggtttc ataactacca
     7621 tttgaatgat aatcagttaa aacatctaaa tatttcccta tttctgaaat ttcccagttt
     7681 ttttcgttct ttgatggggt accaaacatc tcaataaatc ttgatttaac taattcatcc
     7741 aatacttcta tttgctcttt tcttttatct attaactctt gagccttgtc taaaacacgc
     7801 actacctttt cttgcacttt taaattatac atgcgtattt ttatattagc taatccttca
     7861 ttatttaaag ctgattgtgt agcaccttta cttaacctat ttttttgatt tagaaaataa
     7921 ctactattta agtaatggta taaatattga ggcaatattt cttttgatgg ttttaaaaca
     7981 taaaagccag tcgatactat tatattttta ttagttttat taataactag tgttttcttt
     8041 gtgtccttca tttttgcaaa tataacttct cctatattta cagtttgatt tgctctagaa
     8101 ggtttatttt cataagtaac tatttctaga ttgcttatct tgttaaaatc taagtttcca
     8161 gtactaagat atgagcgttc tccatcaaac ttttttacat tttccctgct tatactaaca
     8221 acatctaaaa tttttgcttc atcaaccata ctctacacct ctaacattct ttctagttcc
     8281 tctaatccat ccactatctc tttctctaac accttaaccc tacctataat aacactagga
     8341 gcatcataaa ctacttcctc atacactacc tctttatact tattaataga taaatcatac
     8401 ccattctctc ttatctcttc cacatcaaca aaaaagcttt gctctgttct ttttctatct
     8461 acttccccat caagattatc aaatctctta ataatatcct ctatatcact atcctttatc
     8521 tcatttctct tatcatccaa agaataacca tcagctttca tatcatagaa ccatacctta
     8581 tcagttccac ctgtccctgt tttagtaaat atcattatag ctgtagatac ccctgcatat
     8641 ggcttaaata caccacttgg cattgatatt atagcttcca atttatgatt atcaactatt
     8701 tcttttctta tcgatttatg tccacctgtt gaaccaaaca atactccatc tggcactata
     8761 catgcgcatc ttccaccaat ttttaaaact cttaaaaaaa gtgccaagaa taataactct
     8821 gttttctttg tcttagtcac ttttaataaa tctgctgaca ctgcttcata atctaaactt
     8881 cccttaaaag gaggatttgc tagcaccaat gtaaacttat ctttatctgt attaacctcc
     8941 gataaagaat ccttatactc tatattagga ttgtcaacgc catgcaacat catattcata
     9001 gcacctattc taagcatagt tctatccata tcaaatccat agaacatacc attattaaaa
     9061 tgctccttca gcccttgcac taagaaaaga cttgaatgat tatcccttaa gtactgttgt
     9121 gatgatacta aaaaacctgc cgaacctgct gccgggtcta ctataatatc ttctggtgtt
     9181 ggtttaataa gtcttactat catatctatt atgtgtcttg gagtcctaaa ttgaccatta
     9241 gtacctgctg tagccacttt ggataataaa tactcataca aatctccctt tgtatctcta
     9301 tccttactta attctaaatt actaatacca tcaactattt tagataacat aagaggcgta
     9361 ggaattttaa atattgcatc tcccatgtac tttgcataag ctgattcttt atttccatgt
     9421 aattttttta tgaaaggaaa cacttcattt tgtactattt catacatttt ttctgagttt
     9481 ccttcattag aaaacttact ccatcttaaa tgttgatgtt catcatcaaa tatcttttca
     9541 aaagaaacac ccaaaagagt tgcttctgct tcattttttg tttctacttc atccaatcct
     9601 ttaataaata aaagatatgt aaattgttct ataacttcta atggattagt taatccacca
     9661 gtccaaaatg tctcccaaat cttgtctact ttactcctta attctcctgt aatcatatat
     9721 gactttccct ccagtgttca taaaataatt taaatatata ttttagtcgt acgccttaat
     9781 agttagtgtc ttatgttaaa tccaagtttt tactacacaa ttattaaatt atttttccca
     9841 tttacatatt ttagctaaaa aactaatgca atactcttat tttatgatta ttatatatac
     9901 catacaaaat tattttatca tatatccatc atagaagtca tctacctgga taactcttac
     9961 catattataa ctttttaata ttaatttaaa cttagaaaga aattttttat ttaattatat
    10021 catcttcctt atttcaaatt tctcaactac aatcctaatc aaaaaataaa ataagatgct
    10081 gtctcaaaat agatataatc ttctttttta ttgtcagaat gatgaaaata tatttgattt
    10141 cacacaaaaa agagtgcctc atgaactaaa aagttcattt tgagacaccc cttaatttaa
    10201 tcttacttat tctttccctt tattattaac acttcactgt ccctattgct tttcctacac
    10261 atccacaaac ttccatccta ctcttaacaa aatctttaac tgactctaaa ccttttttac
    10321 catatttctt agggtcaatt acctctgggt cagaattaag cacatcctta accccattgc
    10381 tataagcaat ccttaattca gttgcataat taactttgca aatacctctt tttatagatt
    10441 ccttaataac ctcatctggt attccagacc caccatgtaa tactaatgga actgatacaa
    10501 cctctctaat ttcagataat ctatctaaat caagctttgg ctctccctta tatagtccat
    10561 gtgccgtacc tattgctact gccaaagatg atacccctgt tctctctaca aactcttttg
    10621 cttctaatgg gtctgtatat gctccaccat caccaccatc taaatcgtct tccttacctc
    10681 caactttgcc taattcagcc tcaacaggta tatctgaagg catacatgca tctacaacag
    10741 atttagatat tgaaatatta tcttcgtaac tttcatgaga accatcaatc ataatagaag
    10801 tatatccaac tctaagtgcc tgcatagcta gtccaaagct tgaaccatgg tctaagtgca
    10861 ttgccactgg aacacttgcc ttctctgatg ctacctttac attcgctaaa taataatcta
    10921 gccctgcata ctttattgtt gaaggtgttg tttgcaatat tactggtgat ttaagttctt
    10981 cagcagcctc tattactgcc ataaccatct ccatattttc aacattaaat gcacctactg
    11041 cataatgccc ttcttgtgca tctaataata tttgtttagt tgtcactaat gccataattt
    11101 ctcctcctat atgtttatac tgatttgatt tcttcgttat ttaattttga tactatttct
    11161 ctacttgttt tgctatttaa taactcattt aaaaattctt cattcattaa ttttgaagat
    11221 agttgagata atgtttttaa gtgtaaatta tcaccattat ctgtagctga tatcataaat
    11281 ataatatgtg ccaagcttcc atcttctgat tcaaagtcaa acccttcttt tgatacacct
    11341 actgctacac gtggtacctt tactgcatct gtttttgcat gtggtatcgc tatccccata
    11401 ccaaaacctg tagatgatat ttcttctctt ttaaggattt cttctttaaa cttcttttta
    11461 tctaaaagaa caccagattt atcaagtatt ccaatcattt catcaattac atctgtttta
    11521 ttttttccct taacatctaa aattactgtt tcttcgctat ataaagagat attattagat
    11581 acgttttccg attctgcact ttcattttta tgtccatctt ttgttgcatt tgtattttct
    11641 atagtatttt tctcatttac tactttaggt gtaaccatca tataaagtac agcacctact
    11701 aatgaaccta caaatataca ccctacccat aaaagtggct tattgactaa tcctagaacc
    11761 aaaaaccctc catgtggagc tggtacttct attttcatta tataagttaa aattgatgat
    11821 attgatgatg caatcataag tactggcaac acttttaatg gattttttgc tgcaaaaggt
    11881 attgccccct ctgttatatg agtactacct agtatataat tgattaatcc tgctgctcta
    11941 tcttcttctg taaatctatt tttaaataaa gtagatgcta ttgctattac caatggtggt
    12001 gttatacaag ctgcagatac acctgccata aataaataat ttccctgtcc tagaagcata
    12061 gttccagtta catatgctgc tttatttact ggacctccca tatcaaatgc tgacatacat
    12121 cctattacta ttcccaaaat tataggactt gaattttgta accccgatag aaagttcatc
    12181 atagcattgt taagtgctga acatggtcca ccaagtaaca acattgctac acccacaaga
    12241 cctacgctga caataggaat tataaaaatc gatttaagac cttctaattg tcgtggtaat
    12301 tttcttaaca aatgtacaaa tagtttaact aagtaacctg ctaaaaatcc tgatatgatt
    12361 ccacctaaaa accccgaacc tgtatcaaat gatatcattc ctccaacaag tcctgccaac
    12421 ataccagctc ttcccgatat agattgagct ataaatgctg ccaatacagg aaccatcaag
    12481 ttcatagaat atccaccaac agattttaat gtagctgcta tttgattata ttgttctgaa
    12541 tttgggtcaa atgaataaat cccccataaa aatgatatag cagtaagtac tccacctgct
    12601 actactaaag gtaacatgtg agatacacca ttcattaagt ctttatacaa cttttgacca
    12661 aacgataaat ttccttcttc tgcaatttta ctgcttgata agtttccttt tctaatagct
    12721 acttttccat caatacacct ttgtataagt tcattagcct tatgtatacc ttctttgaca
    12781 ggtacttcta ttaccggctt tccattgaat ctgtccatat caacattttt atcacaagca
    12841 actattattg catctgccat ttcgatatct tttgctgtta acttattttc tacacctata
    12901 gctccattcg tctcaacttt tatgtcacac cctaattccc ttgctgaatt ttttaatgct
    12961 tcttctgcca taaaagtatg agctattcca gttggacaac ctgttacccc tagaatcatt
    13021 ttctttccca tctttatacc acctttctga ctcttatatt ttttatataa tcttccacat
    13081 tctccaaatt acctatacca ttactttcag ccacacttgc tcctgttgct gctgaccttt
    13141 ttaatgcttc ttcaatatgt tctggatttt ccaaccatat acttaaaaaa gcagctaatg
    13201 cagaatcacc agcacatgca gagctgacta ctgtaactgg ttgagcacta gcataataaa
    13261 ttgattttcc attataaaaa taagaacctt tttctcctaa agttagcaat atattttgag
    13321 caccttttaa atgcagtaat ttaagtacat ccttaatatc ttcttcatct cttacaataa
    13381 ttccaaatat atctttgatt tcttcatcat ttggttttat caaatatgga ttatactgta
    13441 gtaactcctt taattttggt gaacttatat cgagtattgt ctttatactt ttatttttac
    13501 aaattttaaa tatatcctca tagtaattat catcaatacc aggaggtaga cttccactta
    13561 ttgataagta acttatatct gctaatgact gtatcttatc tagcatatct agtttttgtt
    13621 tttcgtttac atatgaccca gagtttacaa atttaaattc atcacttcca tcatttaaaa
    13681 atatatttat acgagttgta tcttctaccc aagtaggtaa tacgtcaaat cctctctttt
    13741 cgctttcttc aactatatat tttcctgaaa atcctccaaa aaatcctaat atcttagatt
    13801 ctataccata atgacctagt acaaaagtta catttaatcc ctttccatta ggagaatata
    13861 cagcatttga tgtacgattt actaattttc tctttatccc attagtagat atattcatat
    13921 ctattgcagg attcgtagtt aatgtatata tcattgtctt cccccttgct tgtgctgtgt
    13981 atgttttcat tataataaaa aagtctatga aaatcttttc acaaatagaa aatcgatttt
    14041 catagacttt tcaatttaat tttcagaatt attatatctg accatataat ctataattat
    14101 cctagatata atatacaagg gcaatctgga agatacttca tattcagaaa ttgatatatg
    14161 ttcatgtttg tatcctacaa tatataaatc cgaatacttt ataagttttg cactttcact
    14221 acaacagcaa gttataacct tagctccaac taaattggca ttctgtgctg attctacaag
    14281 ctctatggta tttccattca atgaaaatat gattataagt tcgtcttttt ttattgattt
    14341 agattttatt ttcattatgt tggggtcatt tataaaaaca acattaaaat caagtaattg
    14401 caatttaaga ctaaactctt ttgctacata ttcagtaagc cctcttgcca aaatatatat
    14461 cttactagat ttatttatag tttttattat attgattagt gtagttaaag atatttgttc
    14521 tataactctc tgtgcttcta taaaggattt atttattata tcccccatat tttgtatatc
    14581 atcattttca tcttttactg ttaatctata cctaagttca ttgaatccat ttaaaccaca
    14641 ttttctaatt gctcttgaaa cggttgctgg agatgaatat gtttcatgag caatctctac
    14701 tatagataat tctggtaata ttgattcatt ttcatttata aatttaatta tttcaagttc
    14761 cgtcttcgtt agattttcag aattactttt gtttagctca attatcatat gttatctccc
    14821 cttatataag ttttatttgt ctaaatttat cgagtaatat aatatattac ctcttaacta
    14881 cttattttta tatacaatta agatttagtc aatgtctata tatgtaaatt tataatataa
    14941 taattttatg cttcaattaa ttatgtaatt attagagtat tttgtaataa aaattggagt
    15001 tactcaatta ctgaaactga gtaactccaa ttcttacagc ctcaaattaa ctcgaattat
    15061 tgaaaatgat tcataaacat tatcctatac tctcacttat caatttatat acttgagtaa
    15121 tacctttttt tattaacaga aatcatctta ctaacaattg aaattgtagt tccagtacat
    15181 aatattgaaa atatagttcc aaaccctaaa tttccgccta aatatacacc taaaattaaa
    15241 aatattaaat ctgctatagt ttttaaaact ttatatggat acttaaattt gccctcaata
    15301 tagattaata tagcatctaa agggctcatt ccaatgtcaa attttataag cattgcaaat
    15361 ccactacaca taagtatatg tccaattata aagctcatta ttctaatgat aatccctaaa
    15421 ctacttatat taaaatctaa taataaatat atatacaaat ctataaatat tcctgctact
    15481 aatacataaa cacagcttcc taatcccaaa ctttttttat tcaataacaa tgctataagt
    15541 aatagagttc cattatatat tagccctgct attgtataac ttatacctaa ctttatatgt
    15601 ataccctcat ttaaaagtgt aattgcatca ctaccaaggc ttgactgaag tataagagat
    15661 ataccacatc ccagtatatt tataattaaa attacaaata taaatttttt tatgacattc
    15721 ataattaata aaccacctta tttataatta taatccctct tataaaactg tattaataac
    15781 atagtattta taagagggat tatttatatt taaaaactat ctactttttc ttttaattct
    15841 tctccattag ttcttattac atttttatac caataaaaac tatctttttt gtaacgttct
    15901 ttgcttccat ttccattgtt atctatatct acatatataa atccatatct tttttccatt
    15961 tcttgagatg aacaacttac tatatctatt ggcgaccaca tacaataagc taatatttcg
    16021 gttccatcag ctatagcttc acctatttgt tctatatgtt ttcctaaata atctattcta
    16081 taactatcat gaacttttcc atcttcaaat ttatcatgca ttccaaatcc attttcagct
    16141 atcattattg gcttttgata tctatcataa tattgagata aagtattgta taatccttta
    16201 gggtcaattg cccaccccca aggatttgct tttaagtatt gattttttac attatcaatt
    16261 ggattcatgg tatttttact tgctgatact gttgtagagt aatagtatga tagagctaga
    16321 aaatccatag tattctcttt taacacttta tcatcacctt cttccataac tatatttatg
    16381 ttattttctt tgaagaatct cttaatataa gctggatact cccctctaaa acttacatca
    16441 gtaaaaaaat attgtattct atttcttttt aaagcaaata ctacattttc agggtcgcaa
    16501 tcttctggat aagatgtaca atctgccatc atcatcccta tcatcatatc tgaatttatt
    16561 tcttttccaa gcttcttagt taaagctgta gccatgaatt gatgatgaat agcttgatat
    16621 ttggcctctt ctacatcatc tacctggtct acacaaaatg caactgaatt aaatgattca
    16681 tgatacatta aatttatttg gtttataact atccaatatt taactttatc tttgtatcta
    16741 tttaatatta attctgcata tctaacaaag aaatccacta cttttctatt agaccatcct
    16801 ttatatttta atactaaatt caaaggagtc tcataatgga gtagtgttac aataggttcc
    16861 ataccattat ctattacttc atttataaga ttatcataaa actttaatcc ctcttcatta
    16921 ggctctaaat catctccatt tggaaatatt ctagcccaat ttattgaaaa tctaaaacac
    16981 tttaacccta gttctttcaa aagctttaaa tcttctttgt atgtatgata aaagtctatt
    17041 ccattacgct taggataata cccattatta tctttcatag caaactttat tttatctaca
    17101 gtcatatcag actcgtaatg tttagatata tctctatctt tatcatacat atgtacatca
    17161 gctaagcacc accctttgcc accttcattc caagcacctt ctaattgatt agctgctaca
    17221 gctccacccc acaaaaaatc tttaggaaac ttactcaatt taatcactcc ttattttatt
    17281 tatttaaatc atttactatt atttacctta tattctatag actttactat tcctactaaa
    17341 gacatagtta tatttaactc gctgaatatt gtcataagag tatcttgagc atgtgcaaat
    17401 aaaagtgaat gtgctctttt ttctccacta gcttcccctt gtataatgtt agtttgagct
    17461 ctatgtgctt ctgtcataaa ctcttttgct ttagctagtt ttaaatcagc atttttataa
    17521 tcaaaccttt ctaaatcatt aagagcatgt ttaatttctg ttctagcctc acctgcacga
    17581 agtattattt gcattgctac ttctactaat tcttcatcta ttacatgttc ttcagttgtc
    17641 atatttataa tttcctttca acatctaaat ttaagcttct tgactctcta attttagttc
    17701 ttctttttca taagctttaa aaaatggata ccatatcatg aatagcaata ctatatttat
    17761 tgctaaaaca ataagccctc taacatcttg atttaccata aaagtagata taccaaaagg
    17821 aagataccat aaattaaaca ccttactcgg aattgtcaca aatcccatac tcattgataa
    17881 gtaagtagtt attgatatta ctactgttcc tatccacata ggtaacatta aaaatgggtt
    17941 ccatgctact ggagctccaa acattactgg ttcatttatg ttcattatag aaggaacgat
    18001 acaggctctt ccgattgctt ttattcttcc agctctagat aaacacatca ttagcactag
    18061 tggtaatgtt gctccccacc cacctaaagt tatccaacct gtttgaacaa cttcataagt
    18121 atatatatta gttgcaagcc ctcctgatgc tacagctgct gcattagctg caattgcact
    18181 aagctgaatt gcataagtta ttggggataa tacccatcca cttataccta aagaatataa
    18241 aaatactact aagaagttta atagtacaaa tccaggcaat gtttgtgcta tatctgatac
    18301 tggtttaaat atcctaacta ttatttcaaa catatcaaag ttaagtccat aaattagtcc
    18361 ccaacctata aacattatta ctgctatagg taacatacta tcaaaccact tacttacaaa
    18421 atcaggaagt gctgaatctt caccaaaaaa tgagaaagac ccaaataaag acattattaa
    18481 tccggagaat aatcctgcaa ctagtgctac aagcattcct tctcctccaa atctattgaa
    18541 gttaaatata gctccttcat tcgtaatctc tggacgaatc atcattaaca ttaatccagc
    18601 acctgcaaga ccagctacta cactcatact ttcaaatttc ttattcttca ttatttccat
    18661 aggtaataaa aatgctataa atagtcctaa aagtccaaat gtatattgat ttattggact
    18721 taaatcaggt aagaaactta tgtaattctt caagacagaa actatagtta ctaaagaacc
    18781 tacaaatacc ataggcaaaa ctttcattat agttgattga actgattgta cccatatatt
    18841 cttagttatc ttatttacaa caggagtaaa cttttcactt aacaaatcta taaatttatt
    18901 cataaacaat ctccccatag atattttatt tgtttaatat taattctaat gcttcttcta
    18961 aagcctttac accatctaat cttccatatg ctgttttaga tatacatgct actggaacat
    19021 tatattcatc agcttttttt tgtatttcat ctttcatata atctaaatgt ggtcctaata
    19081 ataaacaatc tatttctggt aaatatttat ctatctctga ctcacttcta gcttttatat
    19141 ctgcttctat gccttttttc tttgcactct ttctcatact agttgccata aaacctgtac
    19201 ttgctcctga gccacatgcc aacaacactt ttatattctt cataacaata cctccagtat
    19261 ttttattcat taatttattt cttaatgaat ttttatttga tttgattgta tttatattgt
    19321 acttcctaaa taatttcctt tcacataaat atatttccta ataataggaa atcatttact
    19381 cttaaccaga cacataaata tatagtataa tgtacattat aatacgtaca ttcaattata
    19441 taaatatcat atcatacaga ttttatttta aaactatgag agggaatcta atgaaaacat
    19501 ctaaaaaaga gttattttta aacttcataa aaacgcaaca tgattggata gattcatcca
    19561 cattagctaa ttatcttaat gtatcaacac gttcgattag aaaatatgta aatgaaatta
    19621 attctactgg tgaatttata ttatcctcta aaaaaggata taaagtaaat ctcaataata
    19681 actgtcaaac caaggttgat agttcagaaa atatatcacc tgataacagg ttaaatttaa
    19741 ttttaaaaga acttatagtt aatagtaatg gaattaatat atttgattta agtgaagaat
    19801 tgtttgttag tccagctact attgaagggg atatagtcaa agctaataaa tttataggaa
    19861 gttataattt aaagataaag caatcgaaat ttttattgaa actaattgga aatgagtctg
    19921 caaagcgcaa attaatgagc tctataatat ttaaagaaac gggaagtgat tttttaagct
    19981 tatttgatgt acaaaaaata tatcaagagt ataatttgac caaactgaaa gaaaatataa
    20041 tatatatatt aaaaaaatac aatttgttta taaatgagta cgctataaat aacatacttc
    20101 ttcatttaat gataactata gacagaataa aaaagaataa ctacatagaa tctgtcgaag
    20161 tagtaaacta catagataat aataatgata taagcatttc aagagatata tcaaattttt
    20221 tagagtctga atacaattta actttaacta gtgcagaatt atactactta gtatttcagt
    20281 taacaaacaa aaccacagtc ttaaattatc atgaaatgga tactaagtca ttgccaaatt
    20341 atatagatga acattttgtt aaattaacta aaaaaataat taaaaatgta tatgacttat
    20401 actttataga tttatctgat gatgaatttg ttgtaaaatt tactcttcat gtaaaaaatt
    20461 taatcagtag ggctaaaaat aatcaagttt tgagaaatca aatacctcag aagttaaaag
    20521 attcctaccc tctgatatat gatatatctg tttatatttg taatcaaatt caaattttag
    20581 aaaacataga aatagatgaa gatgaaatat cgtatatatc tcttcatgta ggttcatttt
    20641 ttgatagaca aaaattacta gaagataaaa ttctctgtgc attaattact ccaaattact
    20701 atgatttaca attcaaaata gtaagagacc tcgagaagag atttaatgaa tccatagaaa
    20761 ttattcaaat tttttcagat actcataatc ttgattttga caataaggta gacatggtta
    20821 ttactacttt accaattagt gatagatgcc ctataccttt tgtttatgta aatccttacc
    20881 taaacagaaa agattatgat aatatccaaa gtaaatttat tcagattaaa gatagaaaaa
    20941 atatacttac tgtacaaaat catttagaaa tgtactttag tgaatctttg tttatgaaaa
    21001 acatatattt agatagtgct aaagattaca taaaatttat gggaaatatt ctgtacaaaa
    21061 ataaatatgt caaacccaat tatatagatg atgttcttat aagagaaaaa atgtcttcaa
    21121 ctgcatttaa taacaatgta gcaattcctc atagcatgaa aatggatgct ttaaaaactg
    21181 gagtatgttt aattgttaac gataaaccag ttaaatgggg tgaggaaaaa gttcaaatta
    21241 tagctatgat acctataaat gaaaaagaaa aagaaaaatt caattacata tttgaaagct
    21301 ttattgaaat attatctgag tggaataatg ttaaagaact tactaaggca gataactaca
    21361 gtagttttat gaatagaata gcttatctta ttcaaaatat ctaaatccat taatttattt
    21421 ccaatatatg tttcttaagt tattaacaca aaatagataa gctgtcacac taaaaagtct
    21481 aaattaatat gtgacagctt tttacctaat atactttgct ttaatactac atattttttg
    21541 attgttgtat actagttata agattgaata tttgtgttgt tgtagctgtc atattctcac
    21601 tagcagttgc tttatccatt gcttcttcta ttgtcatagc tctatttact atagaaaaat
    21661 aagcatctat accctcttca ttacatttaa ctgcatcttc tgttgtggct ccagccaaac
    21721 ctattacttt taccccatat ttttttgcca gttttgcaac tcctattgga gccttgccca
    21781 tagcagtttg attatccaat ctaccttcac cagttatgac aaaatctgca tcttttaact
    21841 cttcctctaa tttaatttct tctaatatta tttttattcc agattctaat tttgaattta
    21901 aaaatgctaa aaaagcaaaa cctaatcctc ctgctgctcc tgctccttct acattagcta
    21961 catctttact taagtaattt ttaactactt tggaaaaatt tctaagccca ttatctaact
    22021 cctcaattat ttctgatgtt gcaccttttt gagacccata tatgtatgca gctccatttt
    22081 tcccaaacag cggattattt acatcacagg ctattttaaa cttacattca tctaattcct
    22141 ttaatctatt ttctattttt atatgtctta tttcatttaa aacttttcca cctaatccta
    22201 ctaacttgtt attttcatca taaaactcaa accctaaggc ttgaagcata cctatcccag
    22261 catcattagt agcacttcca cctattccaa ctataaaatt tctatagcct ttatttattg
    22321 cttcctttat tatttcccca acaccataag ttgtagtgta taaaggattt ctaagttcag
    22381 tcggaaccaa tgttaatcct gatgcttgag ctatttctat tattgctgta cttgtatttt
    22441 ttaataatcc atatgttgca tccacttttt tagctattgg tccagtaact tctatagtct
    22501 cttttttacc attcatccct tgaactaaag catctactgt cccttcacca ccatcagcaa
    22561 gtggcaatat ctttacttgc gcatcttctt taaccttcaa tatccccttt tttattgcat
    22621 ttcctgcctc tattgaagat aaacttcctt tcaaagaatc tatagaaatt aatattttca
    22681 tatttatcta ctccttttta tttactcttt attttaaata tataatttta taagcttaat
    22741 ttatctttta ttttatactc tatatttcac tttgtataca acttataccc ttaatattct
    22801 tttatcttat aaaaaaggga gtgtctcaaa atgaactttt tagttcatga gacactcttt
    22861 ttgtataaaa ttaaatatat gtttattatt tcaacaatga taaggaggat tatctctatt
    22921 ttaagataat tcctttttag cactatctaa tcatttttag cactatttaa ccaatatagt
    22981 tttaacttgg ttcattaggc actctacatt tacagagtta ttatctattg atatagattc
    23041 taattctttt tcatttaggt tagtccattt agctgtttta atatttttgt taaatactac
    23101 gttagctgat tttgtttctt ctttagaatt gtaaaatcta actactaatg cctcttcttt
    23161 ttcagccttt tttacaacac ttaacacaag gtccttatta gtttccttaa gtaaactata
    23221 tgaataatct acttctattt ctgattgatt caatttcata gcattatatg gtattttatt
    23281 ataagtttgt atttttgtta aatactcttt agccatattt gcaacatttg cttctagtgt
    23341 agatttttca tgagtgacta ttgctaagtc tatttttata tctcctatca tttgagaatc
    23401 tggagtaggc aactttattc ctgatggacg acctgggcgt cttgccattt cttctttacc
    23461 taggaatcct acacttctaa ataatgttat agctattgtg tcaaattttt tccctactat
    23521 ttcaaactct cttgtactgt ttgtaagaac agctactcca tgctctttgt cagacaatcc
    23581 aacgaatgtt agcattggat atatagaatc tggtctttca ctccattctt cctgttgcca
    23641 aacttccata gcatcatcat acacacttct ctttatatgt ccaaactgat tatcagacac
    23701 agaaaacttt gaagctatat ttgttggtat ataagttcta accctacaat ctcttgcttg
    23761 gttatttata ttgaatacta catttattat agctttatca tttggaacat ttataactat
    23821 atcaaagtca ataaatgaat ctgctctatt attttttcta gcttgtatat cttttggtac
    23881 ttttaatcta taatttatct ttatctcatt attaaatcta tttttcttta tagtggaatt
    23941 tgctactata ttatcgttaa atattaattt ctcatttgga agtggtgaaa aatcatactc
    24001 atctccttca tctcctccat tttccatcaa taatacattt tcaaaagttt tatttaattt
    24061 tttatcagat atctttaatg tcccgttttc attaacttga atagtataaa agtcattatc
    24121 taccatgtca catacttcat aagctttttc taacatatgt tcaacttctt ttatcatata
    24181 cgccttatac cccattgcag gtattttatc tttaaagttt attgtatata ccataaatga
    24241 atcatagttt ccataatgaa caatttgacg gtctattaat cctgcatcta ttacttcttt
    24301 atgtaccact tcaaaatcca acttattatt atctttatca aatatttcaa atgctttcat
    24361 tttagttata acttgggcgt tcactatttc attcctattg taaggcatta agttaaatgc
    24421 tactaactta tctaaagcca tttcacaact cattgcatca actattcttc ttttgtaaaa
    24481 tgttattaat tggtctactt tttcctcagc taagaaaaat ctattcatta tttcctggtg
    24541 aactttatct gaacaacaac atccaatgct gtcatgagca tgatttttca ttatttcttt
    24601 ccaaattaac tctattaatc catgatgata ttcaaatcct agagaatatg caatagaagc
    24661 tagtggctcc aatatgttgg ttatctttga ttctattcta gcatttgctg attttatatc
    24721 cattcttgtt gagaatatac ttctatgaac cctcatatat ttcccatcta aaaattcccc
    24781 ttttattgta tctatatcct tatttttttc tagctcttta aatatgtttt catatctact
    24841 taagaaaaat tttctctctg gataacattc ttttaattta tatataactt caaatatatt
    24901 cttttgaatt ggcatttggt catgtccatt tggaagtatt atatggtcag tagttgcacc
    24961 cttatcaaga accggtaaat atttatccat tcttgttctt agctcatctt cattcattgg
    25021 tagatatttt cctattgcat aacctaatgg aagtatttga accaaaacag aagacccatc
    25081 atcactcttc caattaaact ctgttttatt agttcctttt ctttcagaac atcctctcca
    25141 aaacattgag tattttatat caaacccatt tagtatttgc ggcatttgag cactttgacc
    25201 aaatgaatct ggtaaatatc ctattttcat atattctcca aattcatcac aatcttttat
    25261 tccatacagt aaatttctaa gtatggattc tccaccaact accatttcat cagtttgagt
    25321 ataccaagga cctattatta gccttccttc ttgaactaat ttttttattc tctccttaca
    25381 ttcaggctta actgctaaat aatcttctaa tatagcagtt tgaccatcca tcacataata
    25441 tggatagtta tgattatttt ctaacatatc cattatttct tccatattat ttacaagtaa
    25501 tattctagat tcctcagttg agaagtacca ttctctatcc caatgcatat gaggaactat
    25561 gtgtacattt tttttcattg cttatcctcc aaaacttatc tgataatatt ttctgtctaa
    25621 ttaaaaatcc aataaaaata ctactgagtt tacacaattt tttaatattt attttatcac
    25681 tataattaaa cctttgattt aaatatctaa taacgtatct tttaatgtat ctttctttga
    25741 tttttttgtt tcctagttat tattaataat attgctgata ttatagctcc aagtactgcc
    25801 gcaaagaacc atattgatgc tataataaat cctgacatac ttccctctaa aagcgccaat
    25861 gagaatatcc ccgctccagg cacttgaaga cctatattga agaatgctac tatagaccca
    25921 gttatggctg aaccagctac taatgatggt ataacatgga ttgggtcctc tatcataaat
    25981 ggtattgcac cttcagttat tccagccaat cctaatatcc aagtttgctt tcctatttcc
    26041 ttttctgatt ctgaaaataa atctctgcct aaaacagtag ctattgtaac tccaaaagct
    26101 gagaccatct taactgatgc aaatattgca taaggtataa aatttccact tgctattgct
    26161 cctattgcaa atgtataggc tgctttattt attggtccac ctaagtcaaa tgaaaccata
    26221 gctcctatta ttgcacctag tagtattgca tttattccag tcatcccatt taaccaattt
    26281 ataagaccat tgttaagtgc tgctacaggc tttcctatta caaataacat caataaacct
    26341 actaccaaag aaccaactac tggatatacc caaaaactta cgaatccagc taatgtgcct
    26401 ttggctggta tattcttctt taaaaatttt actatataac cagcaagtaa acctcctaac
    26461 atacctccaa gaaatccact acctattaaa tcagctgcta gacctgctgc aaatcctggt
    26521 ccaagacctg gtttttcagc tagtgagtaa gacatatatg ctgataatac tggaaccatc
    26581 aatgtaccta acatccctcc agaaagcttt cttaattgcc ataaccaaga accttcttga
    26641 ttgtatagtt cttgtaaacc aaatgcttga gatgctaata ctgcaaatgc aagtatcata
    26701 cctcctgcca caataagtgg tattatatga gatactcctg taagtattgc tgattttaca
    26761 tcttttttcc atgatgattt ttcacaatat gatatatcag atgatttttc tatataatca
    26821 cctttacctt gtttttgtgc tacttctaaa gcttcgtata ttatttcttt tgcccttttt
    26881 agtggagctg ctactgacgt ttttatgttt ggcaaatgtt caaatctttc tgtattttta
    26941 ggtgctacat ctgttgcata tattattgca tctgcctttt ttattatatc tggtgtatga
    27001 gggtccacca taccattagc tccttgcttt tctacataca catccacacc tatttctttg
    27061 ccagctttaa ttaatgcttc tgctgacata tatgtatgtg ctatacctgc agggcatgct
    27121 gttattgcta atacaatttt ttttgattca ttttgaatcc taatctcttc ttttatttgt
    27181 tctttctttt cttttatatc taagttatta aataactctt tcttagtttt tgaatttaac
    27241 aacatattca tataatcttc attagacagt ctagtaacta actcagaaag tatttgtatg
    27301 tgtgtatttc caccttcact ttctggtact gctattaaaa atattagctc tactttatta
    27361 tttgagtcta cgctttccca attttctatt ggtgtctcta aggtcatagc tgcaaatgca
    27421 gcttctttaa ctgacttaga ttttccatga ggaattgcaa gccctctttc aaaacctgtt
    27481 ggagataaag tttctctgta cattacagct tctaaatatt cctcataaga tgttaacttg
    27541 ccttcatcat atagctttct tgctaagaac tttattgcgt cttcctttgt ttttattttt
    27601 tgttttaaaa aaacaaggtt ttcatttgtg attttcttaa attccaaaat tacgacctcc
    27661 ttaaatcatt taatgttatg aatatagcat aaaataaatc atgaaaatgt ttttttgaaa
    27721 ttatacacac aatttcttct taaaaaataa ggatttgtgt atttatacac aaatctctat
    27781 cttaaccagt attgttctat tattgctctc ataatcatca taattggaac cttatctgat
    27841 atattgtacc catttacttg tttaattgtt gaatagcaat ataaacttat atctgcaatt
    27901 tgttgcaatt gattttcaca tatatgtgtt agagctacta ccttacaacc cttattaact
    27961 gctgtctttg ctgcttctat aacttctttc gtttctccac ttaaactaag cgcgaaaaac
    28021 atatcttgtt cacctaattt tcctatatca tgaagtactt catgtctttg gctatagtaa
    28081 gttatattat catgcccacc tctaatttct tttactaata tctcacataa aggaatgttt
    28141 tgacctattc cataaactat aatactccta gatttttgaa ttatatctgc tactttattt
    28201 attttttcat aatctattag ctctaatgtc ttttttatat ctgattcaaa accatttttt
    28261 ggctctttat cctcattttt taactcttct tttaaattgt tttttagttg agagaaacca
    28321 tcatactcca tttttttaca tagcctaact atggtatttg ggacagtaaa aaatttatct
    28381 gctaaagatt gtattgataa ttttactatt tcttctttgt tttttctcat atactcaatt
    28441 atcatgtctt ctgtatctgt aaatttatac tcatattttt ttgctctttc ataaaattcc
    28501 atagtttctc ctccatctat tttattattc ataagtaaaa ttcaaaaata ttagctaaaa
    28561 ttttcgttaa tataattata atttaatatt tttaatttat taatgcatac tactcttttt
    28621 attatacata aaaaatgtgt acttcctata ttgatagaga tgattcaggt ttttattttg
    28681 atacatctct atcaatattt ttttagaaaa tacacatttt tttcaaatac ttatttttaa
    28741 ttaaaacttt aggtaatcta ttctttatat ataattatta gacttgaaaa tatctttaaa
    28801 atcaaccaat tcaatattat ttctttttaa ccacatttta acttccttat cacatagcat
    28861 tgcatgttca tatactctct cttgaataag agaagatgat tttataagac tataatctat
    28921 aaatcctgga tgagtaacca tcaatgttat atctttatct aaatttatat atttttcttc
    28981 aaataattta acaaaagatt tatttaactt gtaaaaatca ttctgaggat atttacttgg
    29041 catgctaata catgaatcta aataataggg acaacttggt ataccgtatt cttttgcagc
    29101 atcacacatt gctgatattg atacatcttc ttctatacca tgtatatcaa tatactcagg
    29161 caatttactc atatacaact tgtaagtttc aatttgagca caaacttctt catatacttc
    29221 ttcataatta aaaacctctt tacctgtcag tagttgcgtt cttcttattt tgctagaaac
    29281 aaattttcca ccttcatcta acaaattctt tatcttaata tgttctttac aacaaggttc
    29341 tcctattact aaattaacat gtaaaccaaa acatacatca tcatttttta ccatttctat
    29401 agcttgtctt gaaaaaggca tattcaccat gattccagca cttgtaacaa taccgttctt
    29461 ataagaagat attatcccta gtgtaacacc ttctgaatat cctatatcat ctgccctaac
    29521 tactaatttc ttcattttat gcatctgcct gctttctcaa ctcatcaagt tgcatttcca
    29581 tctcatcctt tactttaaca acatccgttc ctatgatgat ttgaactgat gtattactca
    29641 atttaattac ccctttggct cctgtttttt taatattatc atcattcaaa atagtggcat
    29701 ccttcacttc taaacgtaac ctcgtcatac aattattaag agtcactata ttttcataac
    29761 caccacaatt tttaattatc tgcttagcca tatatgaaaa attaccatga gaaagtttta
    29821 aattcttttc tttttcacta actttatcac ctatctctat ctcaacttca tgtcctggtg
    29881 tttgtacatt atcttttatt attatatatt taaatgttac ataatataat acaaagaata
    29941 caactcctac aggtataact aaccacgctt tatctccata actaaaactt aagacatagt
    30001 caattatact tgctccatta aatgaaccca agcgagcacc cagtaaatat agtacaactc
    30061 cacctagacc agaataaaaa gaatgaatta tatataactt tggagatgca aataaaaacg
    30121 aaaattctat tggttcagtt actgttgcca taaaagaagt caatgctcca gcggtcattg
    30181 caccttttac ttcttgcttc tttttatctt gtgctgtttt atatatagca taagaaatag
    30241 caggtattga aaacatcata attatgtaaa atcctgtcca gaagaatcct gcatttgggt
    30301 ctcctgccat aaatctagga atttctcctc ttataacttc tcctgttgat gttgtatatt
    30361 cacccatttc aaataatatg taagcattta aaacttgatg taacccagtt ggtattagtg
    30421 cacggttaca gaataaaaac aagaatattc ctattgcacc agctcctccc aaccaaaaac
    30481 caaattgatt cattgcagct tgtggatata tccataataa actaaatata tatgataaaa
    30541 ttaaagcaac cactggtgat agtgtaatta cacatttttc tcctgcaaag aagcttaaaa
    30601 atgctggaac tttaacttta tatgttttat tgtaagtcca tgctatacaa gctccaacaa
    30661 ttatcccacc aaatacacct gcatttaatg tatcattcaa taactctaaa tttgacttaa
    30721 atatcatata tgcaactacg gctgcaacca ttacacttgt cttgtcttta gactttgaat
    30781 aagcactaac tgctcctaat aaaaataagt agtccacatt tgaaaatact atattagata
    30841 tattagatat agctggcaca ttaagcatat ttggaccaaa taataatcct aatatacctg
    30901 ctgctggcat tacagctatt ggcaccagca tagtctttcc taaaagtgac agttgttgca
    30961 tcattttgtt taagaacctc ttcatatcca atcccctttc tatttcggtt taattttttg
    31021 tgaaaacgat ttattcacat tttatatttt aaatattata tttgtttaaa caaattgtca
    31081 atatttttta ttcattttat ttttatcatt tagtttcata tctaaatcct tttaagtata
    31141 ttgctatatc tagcctattt tttaaattta ttttttttat ttttaaaata tgtttaacca
    31201 tgtatttgaa acaacccaca aaatagttca aatttatcct ttttatggtt tatataattc
    31261 tattttcact atacatgtct aaacacattt gatataattt gttcatatca gttcaataat
    31321 attactaaag acctttaagg agggataggg gtatatggct aaaaataaat tttcagagat
    31381 atatgaagta ttgaaagagg aaatacttga tggtaaatat acaagtaata tgatgctgcc
    31441 tactgaactt caacttattg aaaggttttc atgtagcaga aacactgtac gtagagcaat
    31501 ttctcaatta aacacagaag gatatgttca aagtataaaa ggcaagggtg ttgtagtgtt
    31561 agaaaatagt tgttctaatg atttttttct aaatatgcac aatttcaaag gtgtagaatc
    31621 gattgtagaa gataaaaagg ttaatactgc tactagtgtt ctccacttca gcaaaatctt
    31681 aattgataat aagttatcta aaaagacagg ttttaaagtt ggtagtgaag tatattacct
    31741 tcacagacta agatatattg ataacatacc taaaattctc gacattaact attttctatg
    31801 tagtatagtt aaagaccttg atgtttctat agcacaaggc tctatttata aatatataga
    31861 agagtgtata ggtacaaaaa ttgtttcatc cagaaagata tttaaaattg aaaaagctac
    31921 agagcttgag ttaaaaacgc tacctctaaa tgattataat tgtgttggtg ttattaaaaa
    31981 tagtgtatat actgatgatg gaaagctctt tgaatataca gaatcaaagc atacacctga
    32041 aacatttgta ttcatggatg ttactcaaag atattaaaaa aattatgttt aattaaacat
    32101 aattttttta cgtttagaca ctttatccca tactaacctc actattctat atacaattat
    32161 atgtttatac aaataattat ttattgtata ttttagcttt aatattagtt taatacttga
    32221 caatttgttt aaacatatta taattaactt ataaattaca ggaggtatca attatgaaaa
    32281 attggtggaa aaaagcaact gtctatcaaa tatatccaaa aagtttcaaa gatagcaaca
    32341 atgatggtat aggtgatata aatggtatta tagaaaaatt agattatctg tattctttag
    32401 gtgttgattt attatggttg actcctatgt acgtttctcc tcaaagagat aatggatatg
    32461 atatagaaga ttattataat atagacccaa aatatgggac aatgagtgac tttgaaaaac
    32521 tcttaaaaga agctcataaa agagacataa aaataatgat ggatatggtc ctaaaccata
    32581 catctactga acataaatgg tttaaagaat ctaaaaaaag caaagacaat ccatatcgtg
    32641 attattattt ctggaaagat gctaaacctg atggttctgt tcctaataac tggatatcca
    32701 gatttagtgg aactgcttgg aaatatgatg aaactactaa ccaatattat ttacatttat
    32761 ttgaagaaac tcaagctgat ttaaatttgg aaaatgaaaa ggttcgtgaa gaatgttaca
    32821 aagtactaga attttgggct gataaaggta ttgatggttt tcgtttagat gtagtcaacc
    32881 tactctccaa aacacctgga ttacctgatg accctataac agggccaaaa ggagatggaa
    32941 gaactcatta cgctgatggt cctcgtatac acgaatattt acataatatg aatcaaaaag
    33001 ttttcaaacc taaaaatata gttactgtag gtgaaatgtc atctactaca cctgaagagt
    33061 gtatcaacta tactagagaa aatcgagaag aactatctat ggtttttagc ttccatcata
    33121 tgaaaacaga ttataaagga ggcgcaaaat ggactaatga aatgttctct ctggataaat
    33181 taaaaaaagc acaatctgac tttcaatata aaatgtatga aggaaaggga tggaatgctc
    33241 tattttactc taatcacgac caacctagag ctttatctcg atttggagat gatagatttt
    33301 ttcgtcaaga aagtgctaag atgttagcca taacactatt tggtctacaa ggtactacat
    33361 acatatatca aggtgaagaa ataggtatga caaatgccta ctttactaaa atagatgaat
    33421 atgatgatgc tgaaagtaag aatgcatact atcatatgat taaatctggt attgatgaaa
    33481 aggaggcatt gcttatactt caacaaaaat ccagagataa tgcccgtact cctatgcaat
    33541 gggataatac tatttataag gggttttcta atcataaacc gtggttaaaa gttaataatg
    33601 acaatattag tgtagaaaat gagcttaatg attctcgttc agtattttat acttatcaaa
    33661 gattaatcaa atatcgtaaa caatatgata tttttacaga aggtacttat agattgttag
    33721 atgaaaatca taaaaatcta tttgtttatg aaagagagta taaaaaccaa aatcttcttg
    33781 ttataagtaa ttttactcat gataatgtag tatataaatt acctgaaact tatttgaata
    33841 aattaaacta cacaatactt gaaaccaatt acactagaga tataattgaa aataaaatgg
    33901 aaataaaacc ttacgaaagt ataatgatat attataaata aagttattta tataaaaatt
    33961 ggtataacac cagggtgtta taccaatttt actaaattca aaataacatt tatagaatat
    34021 ctatagatta caataattat ttgacttcta catcattata tttctttgaa tatactttag
    34081 tcatatagaa atatatagga actacaatta tcatcccacc taatccccaa actatcttca
    34141 taggttcatc aatacctgct tttatcagta ataatatact tataataact gcaaatattg
    34201 gtataattgc tcctccaggt attctaaaat ttacatcttt atcagcatac ttctttctca
    34261 atattagtac agctaaacat gtaggaatat attgaataaa tctagataca acacttattt
    34321 gagataatgt tgtgaatgaa cccgaccatg ctattagtaa agttcctatg acagatacta
    34381 taattgctat ataaggagct ccatttttat tagtttttct tatagactta ggcattaatc
    34441 cttgttcaac caaagcagca gcagaccttg gtgtaaatat ggatgatgca atatttatac
    34501 ctccaacaga tactatagtt cctattgtaa ttatataccc acctatagga cctagcatct
    34561 taatggcagc atctgcaaca ggagtagctg accctgccaa gccattaccc aacaccccta
    34621 tacttattcc cagtataagc atatatatta ctgatactac aaacattacc attaccaatg
    34681 ctttaggtac atttttctta gggttctcca tatcttttgc tgcaacagct aaagattcaa
    34741 atcctgtaaa agcataaaat aaagttatag atactgctac aaaagctgat gacgcacttt
    34801 gacccttttg tattattaca aatggggtaa aattagaacc ctttataaag aataatccta
    34861 cagctataaa taaaactatt ggtaataatt ttcctatagt catgatatta tttaagtgct
    34921 tagattgttt cattcccata aaatttataa tcccaagtcc tacaactaat ataccaatta
    34981 ttatattttt aataagtggt tctgctgctt gtggccatac agatgatagt gttacagcaa
    35041 aaaaatttgc catagtagcc caagcaatca tactaactat ccacttcata aatccaactt
    35101 caaatccaac aaaatctcca aatgcctctt ttgcataaag ataaggccct ccatcagtat
    35161 caaaccaact acctgcttca gcaaaacata aagcaataga aacagctaaa agcatacaaa
    35221 aaactaatac taatatactt gctggaccta tatctgtata agcatcacca ggtaacccga
    35281 atatacctga ccctattatt gcattgattc ctaatagtac aatactccaa aaacctaact
    35341 taatgccttt ttccattgtt attcccccca aagccaactt aatatattta tattttttat
    35401 ttagatgctt ctttaactat tgccataaat atttttttca tattatcata atctctagtc
    35461 atcatttctg gatgccattg tatccctatt acaaactcac ttccttcctt ttctatagct
    35521 tcaattaaac cgtctttaga tgtagctgaa acaatatatc ctggtgctac tttgttgaca
    35581 actaagtgat gaaaactatt aactaaaact tctttttctc ctaatatttc atataatttt
    35641 gtcccctcct ttatctgtac tgtatgtgta ggtacattag atagatgttg ctgattgtgt
    35701 ttaatataag caccttcaat taaagataaa tcttgataca aactacctcc ttcagttaca
    35761 tttataattt gttctcctct acatatacct aaaactggtt ttttcatatc taaagcatgt
    35821 tttaataatt tcatatcaaa actatctctc tttggtgata ttgcccccaa cttattatga
    35881 ggttcttctt tccatatgag tggatttaca tcttgtcccc cagatagtat aagcgcatct
    35941 atattagata cctgctcctt tataatctca tcatcatata caatcggtac aatatatggt
    36001 atagctttac acataactac tgattgtata taatcattat ttacataagc cctttcatag
    36061 ccaggaaaca ttcctccttc atcaattagt aaattacctg atattcctat tattggatat
    36121 ttctttttaa ccaatttctt caccccttaa cttatttgtg aacaataaaa aatgctactt
    36181 ctcttaaaga gcaagtagca taccaagatt ttatttattt gaacattata attcatttta
    36241 gaaatacttt ttttgaatac aagtaatata aataacttta tttacttata ttttatttta
    36301 atcctgttta gtttgacttt tttaaattgt tttaagtaca actaataggt aaaataggca
    36361 tttagatttt cctttttatc aacctattaa atactgttta atatattttt tccccttcta
    36421 tttaattcac ttccctttct accagattca catattatca aatccagctc ttttaacata
    36481 ttaagtattc cccttacctc accttctgtt atactgtagc ctaattcatt tattgaatta
    36541 acaataccat ttctacctat atttttatta agattattgg cattttttaa acactccatt
    36601 actaacttta ctttctctat agatgttcta tcctttaata tgcttatttc tttactaaaa
    36661 tcttcagtta tatttaataa gttatgaggt aaatcattta ttaaaataac atcctcagaa
    36721 ctcataatgt taatatacat agcagtattt tttaattctc ttatattacc tggccattca
    36781 tatgcattaa taatgtcttg aacaccttga ctaattgctc tcttcctttt cataaaatgc
    36841 tttaacataa cttctatatc ttcttttcgc tctcttaaag gtggtatatt tatgggcaat
    36901 acatttatcc tatagtataa atctgctcta aatctatctc cttttatcat ttctaataaa
    36961 tttttatttg tagccgcaat tactctaaca tctatatcta ttacattttc tcctccaacc
    37021 ctcattactt gattctcttg taatactcta agtaatttgc tttgtaagta tataggcatg
    37081 tctcctattt catccaaaaa tatagttcca ttgttagcct gttcaaataa tcctttttta
    37141 cctcctttta aagctcctgt aaaagcacct tcttcatatc caaaaagttc actttcaagt
    37201 aaattttctg gcatagctgc acagtttatc gctataaatg actgactatg tcttggtgat
    37261 gcattatgaa tagactgagc cataagttct tttcctgttc cactttctcc cgttataaga
    37321 attgtataat cagattcagc tattttcata cctaatttct tagttctttc catcttcgtt
    37381 gaaactgttt ttatatcatc aaaagtatat ctagcaactt gtcccttttc tctaagcttc
    37441 tttgataggt tttgctccaa ttttcttata taagttattt cttgaataca aaaataatac
    37501 ccagtaaccc ttccaaaact ctctatatta tacttattta cgtttaagta cttattatta
    37561 aattttataa cttcatcatg tgccttactc aaactaaaaa tctttttaat attctcattc
    37621 tctaattcat ctatattttt ccctataata ttactttgaa tatctagtat atcccttaaa
    37681 ctattattgc aaataattat gtttccctta tctgatacca ttgccatacc taagtttgat
    37741 aaatttatta tagaatttaa ttcatctgct tttatagtaa gttctttgta tttagtattt
    37801 attcctgaat ataaactaat tatttcatct gtatacttaa ttagcctctc agtaatttct
    37861 ttatcatcca gtttgagttt tgctattatt tgaataaacg ttgaactatc aatataccta
    37921 tggcctaaat caataacttc ttctatatat tttggaacta aacttgactc tcctggcgtt
    37981 atagctatct taatatttct atattcttca ttgggattgt atggtataaa attcaaatgg
    38041 tttattccta tattgtataa attagatatt gtttccaata cagtatgctt attatcgttt
    38101 actactaata catctatttc ttctggcaat gaaaataact tatatatatc cttttgcttt
    38161 atgctcctat ttatagttat tatctttgag acatcttcta catatttttt tatttttaat
    38221 actctatcat ctatcattac caatattatg tcatctttta ttaattcctt ctctgttatt
    38281 ttatttaaat aataattttt tatcattact ttatctttaa atatcatttc tagattttta
    38341 tttaagaaac attctaattt agacaaccca tcagttacta ctgctattgt tttcatttga
    38401 ttactccttt taaaatatac tctactcttt tataatatac atctgatttt cactttaata
    38461 gcacaaaaaa ttgtacattt agtatactaa catattcctt tattagtttt atgtccctaa
    38521 atatcatagt tgcaatatct atcatatttc ttaaacttct ataaagcaaa aattgtgcca
    38581 aattaataat tttcttaatt ttattctaaa gttcctcaat agtatttaca gacttagcac
    38641 ttatagctta taagtcttta tattattaat ctatttttat aggttaattg tacaaatcat
    38701 atatcacttt tacctattaa atgcattata aaaaagatgg aataacgatt cgtcactcca
    38761 ccttttttgt aataaaaaat tgtatatata aacactattt actactcttc taagtacaaa
    38821 cagtatctac atactataac ctttcaccat tagattctat tacttgttta taccagtcaa
    38881 aactcttttt cttaatccta gacaagtctc cacttccatc atcatactta tccacgtata
    38941 taaacccata tctcttggtc atctcaccag tagatgcact tactaaatct atacatcccc
    39001 atggagtata tccaaataaa tcaacaccat cttctacagc ttccttcatt tgctctatat
    39061 gtgcttttaa atactctata cgatagtcat catttatcac tccattagat tcttttttat
    39121 cataagctcc taaaccattt tcaactacca tcataggtat tctatatcta tcataaattt
    39181 catttagtgc atatctaagc ccttcagggt ctatttgcca tccccattca ctagacttaa
    39241 gatatggatt tttcactcca cctaatatgt tgccacttgt attatcttct ttagaatcac
    39301 tacttacaca tgtagacata taataactaa atgtataaaa atctacacaa ccttctttta
    39361 aaatttctaa atctcctttt tccattttta tttcaatatt attttctcca aaatatctat
    39421 tcatataagt tggatattcg ccacgcactt gtacatctcc acagaaataa ttcattactc
    39481 tactatctct ttgagtttta actgcatcat ctggattaca agtataagga tacattgttg
    39541 caaatatttg catacatcca acttgataat ttgaatctat ttcatgagct aatttaacag
    39601 ccttagcact tgctacaaat tgatgatgta acccttgaaa acgaagttga ggtatatcta
    39661 cttggtttat aaaatctgta gtcccttcat ttaatattcc ttgtgataag tagcctccca
    39721 taggcattgt agctgaattt atttcattaa atgtcagcca atattttact tttcctttat
    39781 atcttttaaa tattgtttca cagtaattca tatacaagtc tattacctct cttgaaaccc
    39841 atccattgta tttctctgtt attgcaaatg gtatttcata gtgagatatt gttattaatg
    39901 gttctatatt atattttaaa cattcatcta tcacattttc ataaaattta agtcctgctt
    39961 catttggttc tttctccatt ccagttggaa atattctagt ccatgctatt gaaaatctaa
    40021 ataccttaaa tcccatttct gcaaataaag ctatatcttc tttgtatctg tgataaaaat
    40081 ctattgcttc atgacttgga tagaatgttc ctttttctat aactctcgtt attcttttac
    40141 ttactttttg agaaccccca gtacacatat ctgaacaaga aggacctttc ccatctaaat
    40201 tccatgctcc ttcacattga tttgctgctg ttgctccacc ccataaaaaa tcttttctaa
    40261 gtaccattac tctacctcca ataatttatt tatagtaaat ttattttaaa ataaaaatac
    40321 atatatctaa tttttaatta ataaaactct cttttaagct aaaacagtta tcaattcctg
    40381 actattattt acatgctttt gtgtattttc tataatatcc acataatcag aataattagt
    40441 aacaactact ggtgtttcta agcaatatcc ttcttttgat atgctttcta tatcaaaagt
    40501 tattaatgtc tgaccttttt taatcttatc cccttgatta acaaaagatt tgaaatgttt
    40561 accttccaac tgaatagtat ttaaccctat atgtatcaat agttcacaac cattatcaga
    40621 tataattcct attgcatgtt ttgttggaaa taaagtcatt atagtcccat caaatggtgc
    40681 cactactttt ccttctttag gtgttattgc tacacctttt cccaatatac ctgttgaaaa
    40741 cgctgcatct tgtatctgct ccaaagcctt tacttcacct tttattgggc tatatactac
    40801 ttctcttttg tttttttcta caacgccttg cccattatta tctttagaaa tttctactat
    40861 agaatcatct ttccaaaaaa ataatgttaa aacaaatcct actacaatag ctactattat
    40921 tgctattata gttgcataaa cacctttcat atctccagtt gttggattta tataattagg
    40981 tataccaaat attccaagtc cacccattac ataacttttt acattcatta tccccattac
    41041 agctcctgcc acagcaccac ctacacaact atatatgaat ggtgtttttc ttggtaaagt
    41101 tattccatat attgcaggct ctattacacc acatatccct gaaataactg caggtataca
    41161 cagctctttt atcttcttat cttttaattt aaagtacatt gctgctacta ctgatgtttg
    41221 tgcaaaagat ggtacaaatg ctcccactaa tattgtgtca aaccccatag tcataaggtt
    41281 tgacatagct attggtacta atccccaatg tagaccaaat attacaagca cttgccacaa
    41341 taaaccagtt aatacaccac ataaaattgg tgaaaagtta aataaagcta aaaatccatt
    41401 tccaactata ttagaagcat aggtagctat aggccctata accataaatc ccaatggtaa
    41461 agaaactaat aaaactgcca ttggtacaaa gaaattcttt actacatctg gtattatttt
    41521 agcaaacact ttctccaact tagctgctaa taatactatt ataattactg gtactactgt
    41581 tgaagtgtag ttcattgcta ttactggtaa tcctaagaaa gttatatata ctggtgattc
    41641 aaatattgtt ccagtaaata gattgtataa aggttgacct atagatgcta gagtatctaa
    41701 ttgaatacct gaatagcata aaactgcacc tataagcatt ccaataaatg gttttaattt
    41761 gaatttctta gcagctgtat atccaagaat tattggcata tactggaaca ttgcatctcc
    41821 gattgcattt aacataatat atgcaccatc agtttctcca tacaaaccca atgctgtaaa
    41881 tactgcatta aatcctttta tcataccagc agcacacaga actcctaata ttggttgaaa
    41941 aactcctgat attatgtcta taaacttatt aagtaatcct tttggcgcat ctgaatctga
    42001 attatctatt gtatctcctc ctaatccagc caaatcgcac acaacttcat aaacatctgg
    42061 aacatgatta ccaataacta cttggtattg acctgcactt ttcattacag taactatacc
    42121 atccattttt tttagcacat catcatttgc tattgattca tcttttaatt taaaacgtag
    42181 cctcgttata cagtgagata aactgctaat attatccttc cctcctacat tctcaatgat
    42241 ttcttttgat agttgttcat atcttctcat tttttctcct ccattttctt tttgaaatat
    42301 gaaggtttgg ccaacttaat gtcaccaccc aatatatata aacctaatta ttaggattta
    42361 tatctgactt aatactttta cttaccactc tttcaacgtg aatagttaag tataattttt
    42421 cctcatctgt taaatcgtag ttgtattttt tatgtataaa ttcatccaac ttttctatgc
    42481 atttataagc atttttatat ttaactttta ttacatttag taaatcatct tcattatttt
    42541 catgtaaatt attactaaca attcgttctg caaaatactt taagtgagta ataaatctat
    42601 gataataaac tgaatcttca tcaaatacta ttctgtaatg gtatttaacc atatttgaaa
    42661 tttcttgtat tatttgtgta atctcatata tagtttttat actttgatcc atttgtgcat
    42721 taactatatg cagtgctata aatccagctt catcttctga tagtctaatt tcaaattttt
    42781 tttctatata atccaatgct tctaacccta ttttaaattc actcttataa aatcttttta
    42841 tatcccaaag taatacattt tttacactta ctccttcacg agctctttct attgcagtat
    42901 acatatggtc tgttaaagaa atataaatac tatcatttaa tcttttccct agtttttctt
    42961 tagcatataa aattatttca tctgataatt ccatatatct tataggaata tctgctatta
    43021 gttctttaaa tttatcagat atatttgggt ctgaaagttt gaatatctta tcaattttat
    43081 cctttgatat atgctctcct gtacgttttt tataagctaa acctctcccc ataactacta
    43141 tttccttatg attttcatca gttgtaataa ttacattatt attgagtatt ttttcaataa
    43201 tcattgtgat gcccccttta ttagcattaa gttaaaataa atctttttta attatttaga
    43261 atatttaaaa tgtaatttat tacataaaaa aaaacctatt tattacacat taaatagact
    43321 cccatgagtc ctgagtaata aataggttta gcttgtattt aaacaatcac tatccgtttg
    43381 tattttattt taattattat ttattatatg ttagcaaatt tattttttag tgtcaacttt
    43441 ttctcaatat tttaattcta aataaattat ataaattgca tctgcaaagt actattttta
    43501 taaataaaca aaataaaaaa ggtattactt gctttaagta atacccattt atttttaatt
    43561 taagtggttt ttcttaatct catcaagtag tccatcttct aaataaattt ctaatgcaca
    43621 tcctaccatt gcctttactg ctttgtgaag tttatcataa gcttcctcag aatttgcata
    43681 atttagaaat tctttttcat gaacatatac cattggactt atatctaagg ctatttctgt
    43741 atacatagta gggcaaactt gacttacatt acctatatct gtagaaccta ctggaccatc
    43801 tttaccttct aatatatctg ttatacctga ctcaatcaaa ttattctttg ttatcttttg
    43861 aagtactttg ttatttatta tgttgtcaaa agaattttca aagtatctat aagaaagctt
    43921 agctcctgtc attaactctg caccttttgc acagtttata acttttttag tcacttcatc
    43981 taaataactt ctttcagcag ctcttacaaa aaacttacaa gctgcttttt ctggaactat
    44041 atttggagcc tctcctccat ttgaaactat tccatgtatt ctaacatctg attttacatg
    44101 ttgtcttagt gcatttatcc cagcaaaagt aagttgtact gcatctagtg cattaactcc
    44161 catatgaggg tgactagctg catgtgctga taccccttca aaactaaact ctaatgaatc
    44221 tattgccaaa gccttacagt ttatattatt aaaagcttct atatgcattt gataacttac
    44281 atcaacatca tcaaaagctc ctgccttaac taaatcacat tttcctcctg ttgtttcttc
    44341 agctggtgtt cctattagta caatttttcc tttaaaattt tcttttaact tacttaatac
    44401 tatacaagct cctagtgtag atgctgcaat ccagttatgc ccacaagcat gagctggttc
    44461 tttattgtct ccatatccag gaagtgcatc atactcagct aaaaatgcta tggtaggtcc
    44521 atcattatct cctaattcag ctctaaaagc agtctccata ttacaatatg gataaactgt
    44581 atcaaatcca tattccttca ttttctctac taagtatttt gatgatatgt attcttcttc
    44641 ccctaattct ggattgttaa atataaaatt acaaacttct tcaatttctt ttccaagttc
    44701 attctctatc tcataagctc tcttctttat actctctatc ataacttacc tcccactaga
    44761 atcctagata taatcctatt gtcaaaaata ccattacaag aattgttaat actaccatta
    44821 aaggaattac gaatctaacc cactttgacc aaggaatatt ggctactgct agtgctccca
    44881 ttaaaacacc tgatgtaggt gttattaagt tagttacacc tataccaaat tgataagctg
    44941 taactatcat ttgtcttgat acatctacta agtcgccaag tggtgcaagt acaggtattg
    45001 taagtgatgc aagccctgat gctgatggta ttaaaaatgc tattaatcct tctattaaga
    45061 aagttaaatt tataaatata gtttttggta atccatttaa taaatttgct gcagaattta
    45121 aaattgtatc tattataaat ccattttctg ctattattac gattccacgt gcaaatgcta
    45181 tacataaccc tgctgtaatt aaatctcctg ctccacttat aaatgaatta actatctcat
    45241 cttgtttaag ccctgatgct attcctgata ttatacctat agctgtaaat atcattgcaa
    45301 tttcagttat gtaccactct agtcttaaaa ctccatatat cataatcgcc atacctattg
    45361 tgaaaatggc tattaccatg gcttctcttt ttgtaaattc ctttatattt gtatcactat
    45421 taaccattga ttcttgattt agtgatatat cgtgtactaa agatttttta gggtcttttt
    45481 taactttatt ggcatacatc ataacaaatc ctatagatat agccatatat attataaaca
    45541 taacaactct aaactctatt ccagaacctg gtactatttg tgataatgct tgtgctattc
    45601 ctacagagaa aggattcgta gtagctgctc caaatccagc tgttgctcct ataaatactg
    45661 tggccactgc tgtcaatgaa tcatatccca tactggtcat aagtggaata aatatcatat
    45721 aaaaaggtag tgtctcttca ctcattccaa acgtcgtccc acctagtcca aatagaatca
    45781 ttgaaatcgg tattattaaa aattgaaact tcttcatttt atttacagta tgagctataa
    45841 cagcttctat agcccctgtt ttattaacta tcccaaaagc tcctccaact attaaaacaa
    45901 atccaactac ttcagctgca tctataaatc cgtttatagg tgctgtaaat acatcagtaa
    45961 ttccttgtgg atttgatggt gctttttcat aagttccagc tacaacaact gaccttccgt
    46021 ctatatctac tctttcaaaa tttccacttg gcactatcca agtaagaatt gccattaaca
    46081 ctattagcga aaatattatt gtaagtgtct gtggcatagt aaactttttc ttttttaaac
    46141 tgctcatttt taatctcccc actttttaaa ttaaatattt tattattgca tccctttatc
    46201 ctattttgta tagatgtaaa aaagctcaac atggatacat gttgagctaa atgtgctaaa
    46261 tacaacatac ctgcatcttc cctttatctt gtttaagata gctctccatc aaaattcggg
    46321 ataattttga tgacagtact gtacctatta aatacagtcc cagcactagc tttggacact
    46381 agcacttcgg cacttactcc ttttatattg cctcattggt ttccaacctc ttcaatatta
    46441 atcttagtaa atgcaacctc tacctcaatc tgttcgttag atgaggtaat tcttattaat
    46501 ttttattgat tcaaagtaat tgtagcataa tatgtcgaga ttgtaaatat tttcagtata
    46561 ataattctta ctttatgatg tcattccatt tttcacaaat aattttttct ccatataatt
    46621 taaatactgt agtatatttt aaatacacac aaactttcca caaattttta attattataa
    46681 tacctttata ataaaaaata aaagccatgt aaacttatca atttacacag ctttatatac
    46741 attaatctac tccaagtaca gctttaagct ttgatgctat tgtaataact cgtggaccaa
    46801 atataacttg aactgagttt ttctttttaa caactccact tgcacccaat tcatttaccc
    46861 agaaaccatc ttcatagaat ccatcaattg aatttagctc taccctaagt ctagttgcac
    46921 agtttgtaac attttttata ttattacttc ctcctaaacc ttctattata gaatgtacaa
    46981 gctttgtatc tttatcatct acttcctctt ctactgcatt gttgtatgct gttttaccag
    47041 catctacaga ttgtctttct ctatattctt tcttactata aagcttaact tcttctgaac
    47101 ttcttcctgg tgtttttata tcaaacttct taattgccca tgtaaatatt atataagtaa
    47161 ctataaaaaa tattggtatc aaaaataata atggtaacgc atccactttt tgtggttgta
    47221 ataaattagg aaacatattt ctaaatgatt ctcccattat agaaacatta aacatttctg
    47281 taaatacata cgtcaatcct gccagtggta catatgctac aaaatacaat aatggtgcaa
    47341 caaataggaa tgtatactct attggttccg ttacccctac caacatggct gttactattg
    47401 ctggtatcaa tatacttatt gcttttttct tattagcatt atcagccaac ttatacatag
    47461 ctaaagctgc tgctggtaat attgcaaaat gtattaataa acgacctgtt gtgaagttac
    47521 gagttatata agatagtgta tctgggtctc ccatttgagc taatcttata ttattaacac
    47581 cctcgtaaat tgctccacct acttccattg ttccacctac tcttgtatat tctataggga
    47641 atgcaattaa gtgatgtata ccaaatggta ataatgcttt atccattgct ccaaaagtaa
    47701 atgttcctaa taatccacta gaacctatcc aattaccaag tttagataat gccaacccta
    47761 ctggtggcca tataaagtac attgctgtac ccaatactat tgatgctata aacatcataa
    47821 tcattgaaaa tcttggacct gagaaaaaag ataatgcact aggaagttct atgtcaacaa
    47881 atttgttatg tactgcacta gctacaaatc cagctattat agctccaaat atactacaat
    47941 catatgaaaa gattcctaag aaagaaccat ataaagaact tcgactatat gcttctgcct
    48001 ctcctaatcc agatgccata aacgcttctg ctgtaactgt atctgaattt ataccatttg
    48061 atgctaacaa tgtacttata actgtgtgca ttcctataaa taaaacaatt cctcctaatg
    48121 caccccatcc tttttccttt ttagataatc caaaagctat acctgtaaca aagaatattg
    48181 gtaagtatct cattaccata aatcctaaat cgtttattac tttaaagaat acatttataa
    48241 atgacccttc ttttattagt ccgctaagcc ctaatgcaga aacgttttcc atatttgcaa
    48301 aagctgaccc taatcctata aatactcctg ctacaacaag taatataaca ggtatcatca
    48361 ttgctccaga aagtacttgt aatttatcct tcatagtatt atttcctcca tttttattga
    48421 aatgccaggc tatataatgc atatatatat acttctattg ctttgtataa tgtatctata
    48481 cttatatttt catttgcctg atgtgaattt ggattatctc cctctattgt gggtccaaat
    48541 gcaactccat tttttaacac tcttgcataa gatgcagctc cttttgtaaa aagttcggct
    48601 tcttttccaa aaccttgttt atatgcactt gataatttat ttattaattc actatctggt
    48661 tttacataca gtaattttaa atccttatat atatcaacta ttaaattttc ttttttccca
    48721 atttcattaa ttctattagt tataaactcc caacttatac ccttaggata tctaaagtct
    48781 attttcatat tcaattcatt tttctctaag aagatactca ttatacatat tgtagaaact
    48841 cccatatcta catcttcttt atatatccct aatttttttc catgattatc atctgtaaag
    48901 tatgaattta aaatatccct tattataacg cctttatcat ttagcttttt aattttctct
    48961 aaatcttttg ctaaactaaa tgcacagtta tatgacctgt gtggatttct cgataaagcc
    49021 ctttctcctg tatatcttac taatacttta ccttcttcta gttcttctat ctctgtataa
    49081 taagctaatg attctactaa atctttctta tcatcagttt taaaaacagc ctcaattttg
    49141 tcacatacaa atccatcttc tttgtttgac tttatatcaa ctaaattgtg atttctaaat
    49201 ttatctttat ctattttctt tcttagattg aagtataaaa taccattttc tccatttact
    49261 attgggaagt ttccatctgg agaaaatgca aattttggct gttcattgac actaaagtaa
    49321 tgctccatac attcccaagt cgtctcttca gctccaccca ctatcaatct aatctttctc
    49381 ttcggctttt cattaagttc tcttaagaaa agtaatgcat ataaaatccc tatcaaaggt
    49441 cctttgttat cattaactcc tctaccataa agatagttat ctttttgaca tactttaaaa
    49501 ggtttactct tccaaagttc tttattatat attggcacca catctatatg attaagcacc
    49561 cctactactt cttctccttc tccatattct atatgaattg catatccatc aaagtctttt
    49621 acaacaaaat ctttgtcttt tgctatttga ataagcttat cgaaggcatt tcttatttct
    49681 atcccaaatg gttgatttat atctgttgta ctttcatctc taattgaagg tatttcaact
    49741 aaacttctaa tatcctttat gatattttct tgattggatt ttaaataatc aataattagt
    49801 tctttgttta ctatcatctt aattatttat caccccttta tattaatttt acaaagcatt
    49861 tcagttcata tctacattat aaattttgaa tattattttt tcaatatttc aaatacttct
    49921 ctaaattacc ataatgatac ggtaaacaat caacagatta tgacaaaatc atactatacc
    49981 tattactaat attttaactt atctattacg tcttttttaa tgtaatttta ttccaaaaat
    50041 agatataaaa agatgtagcc ttagctacat ctttttatat ctattcaact tccattatta
    50101 tgctattaat atctacattt ccaggttcta tcctatcttt tactgttctc ttaacagaat
    50161 cagcatcatc cattataact acaggagtta ttatatttaa atcatttgac gttataaaat
    50221 ctaaatctac ttccattatt aaatctttag cttttacctt atctcctgcc tttaccttaa
    50281 catcaaacgg ctttccttct agtgacattg tctctaaacc tacatgtatt aatatatttg
    50341 tattatcatt actcttaatc attattgcat gctttgtatc aaatacattg actatttcac
    50401 catcaacagg agaatataac ttaccttcat ttggtattat tgctactcca tctcccatca
    50461 tcttttgggc aaaaactgca tctggaacat cttctaagtt cactaaattt cccttaaaag
    50521 ggctatatat tttctcaatc ttattttctt ttttcttaaa tatattaaac ataacacact
    50581 ctccatatta taaaatttta tgataatatt tttcttaaag cttttgctac accatcattt
    50641 acattagtat cagttacaaa atctgccata gattttactt catctgtagc atttcccata
    50701 gcaataccaa gacctgcaaa tttaatcatg gatatatcat tttcattatc acctatacaa
    50761 ataacttctt tgctatctat acctaatata tcacaaaatt ttttaactgc aatacctttt
    50821 gaagtacctt tactcataac ttcaaaattt atctttccag aacttactac ttctaaatct
    50881 tcttgttttt taaattcttc ctttgcttct ctcaaagaat ctacgttttc tgagaaaagt
    50941 atacatttta aaatttcatt atcagctttt tctaataaag tttcacaact tgcattttct
    51001 attatttcaa ttctgtcttc ttctttattt ttactattta ttaatctata tggatgttct
    51061 tcacctattt cattgttgga tataactatt ttacagcctt taaaatgttt gtttaaatta
    51121 tacttttcac ctattgtata gattttcttt atagcttctt tgctcaaaac cttcttatac
    51181 tcatatccca ttaatttaaa atatgtccca ttagttgata taatatatat atcatcccct
    51241 aaaacacttg taaaatattt catagcatta taaggtcttc ccgtaactaa ggctaccttg
    51301 ataccctttt ccatagcttc ttttagtgct ttaatatttt cttctgatac ttcaaatcct
    51361 ttccccatca aagtaccatc catatcagta caaattaatt tatatcgcat ttgtatcaca
    51421 tcctagtaag atttttctaa tatttcaaca aggtcttctt tctttccaaa aggtaaaaat
    51481 cctaaaactg gacagcttgt tatttgttct aattgttcct ttgttacatt aaactcagac
    51541 atttttgtct taagtcccac tctctttaaa aaactttcta tttcatttcc taaagtttta
    51601 gctgcttcat catcttccac tttttctaat tcttggttta gcattctcgc tactttggca
    51661 aatttctcta tattatcctt atagaacttt tctgcaaatt ttgggaacac tatagccaaa
    51721 gcctcaccat gaggaatatg tgtaactcct cctattattt cacttagtgg atgtggtgct
    51781 gctgctccag catttgccag tgaacttcct cctaatgtat ctgctactgc taactttgtt
    51841 ctgtattcta tattattttt atcttccatt actttaggta gatagttaat gactaattcc
    51901 atagattttt cagacattat ctctgtaaag tcattagcat ttggatttat ataactttca
    51961 aatgcatgag taaaagcatc aaatgctgtt gatgcagtaa ttctctctgg cagagttaac
    52021 ataagctctg ggtcaactat acattctttt gagaaacaat tttgatgaaa tattgtattt
    52081 ttctcgcttc ctctcgatat tactgctgct tgtgtaactt ggcttcctgt tccagaagta
    52141 gttgatacag ctattaatgg taattctttt tcacttacct tatcgtatat tttaaatgga
    52201 tttgtatatg tactaaacat ataatcccaa tctatttttt ctaaaccaaa agtcaatgct
    52261 aatacttttg cagtatctat acttgaacct cctccaacag ctaaaacaac atctacagat
    52321 tcttttttag ctaattcgaa cccttcattt attaattcta cagttgggtt tggctctact
    52381 ctatcaaagt gtacaacttc tatacctttt tctattaaat tcaatgtaac tcttttatat
    52441 aacttgtcta atggctctac atttggagta gtaactaaca aacatttctt tccatatttt
    52501 cctattattc taggtagttc acttaaagtt ccttgtccaa aatttattct tgatggttga
    52561 taaaagttaa tcatattttt cctcccttaa attattgact tcatattcaa attatacata
    52621 tcataggatt tttaaggcaa taccttcact gttaactctt atttactaaa gcttatggca
    52681 attattagac aataaatgtt ttattattac catatcatta tgtaaatttt attaagtacc
    52741 catgttataa ttttataatc aatcttattg tataattgac ttaataataa aaatagagta
    52801 tatacacttt tttatgacaa atagcttaaa ggagaattaa attatgaaat atttgataga
    52861 cagtgctaat cttgatgaaa ttcaaaagtg tttaaagtat ggatttaagg gaataacagc
    52921 taatccatct atgtatctta aagagaaggt aaacttccat gaatttattg agacatgtac
    52981 taatttaaat ccagaaatat taactgctga agtcattgga aataatttat acgaattaat
    53041 taattcatgt gataagatat taaatataaa taaaaacact ataataaaaa taaatttctc
    53101 tgaagttggc ttagaactta taaacatatt aaatagtaaa ggtgtaaaaa ctgcatgtac
    53161 cttgattttc aatgtaaatc aagcatcatt agctataaat gcaggtgctg attacctatt
    53221 cccttttata ggtagaaatg atgaaaatgg gaatgatggt ataaaaaacc ttacagaaat
    53281 atgtaacctt atatcaataa atggatataa tactaaagtt gttgcagctt ctattaaaaa
    53341 tgtattccac ttaactcaag catctctttg tggatgtgat tatgcagctg taacatatga
    53401 tttatttaaa aaagcttctt ttaaccagct tacagtagat ggtgccaata cttttgaaag
    53461 agattggtcc aaggttaata aatagtaact aagatttagg agggtttgca ttgaacaaaa
    53521 gattattaga tattgctgaa ttattactca acagctcaga ctatattact gtagatacta
    53581 ttgccgaaga attaaaagtt agtaataaaa ctattcgtaa tgaccttgtt attttagatg
    53641 aatggctttt agagtttaat ttatccctag ataaaaaaac tggttcaggg gttattattc
    53701 taggtaatga agatataaaa cttaaagtta ttagagatat caatgataaa tcaaattgta
    53761 tatatgcata ctctcctgaa gatagaaaaa ggtatattct aagtaaatta tttattaaaa
    53821 attctaagtt taggattcgt gatatttgca atgaactaca tgttagtaga gctactgttc
    53881 ataaagactt ggtagttatt caaaattttt tgcaaaactt taaagtgact ctagttagaa
    53941 aaaccaataa tggagtatat ttagagggaa aagagaaaga tattcgaaaa gcagtttttg
    54001 aacttgctac tgttaataaa agttatactg aacttaaaga aatattattc tcgaactcta
    54061 atgaatgcaa agatacccca tcaacaaaaa tatttaagga gctatttaac tatgattttg
    54121 agaaattatc tcaaatcact ctacacacct tacaagtaga aaaaagtaac cttagtgatg
    54181 agtattatat aaacttctta atacatatag ctatatgtat taagagaatt tcaattaaaa
    54241 gatatattaa cttatctgaa ggttttttta gagaattatt agaacatgaa tactttgaaa
    54301 aatcaaaaat tttatgtgct aacctaagtg aagcttttga cgtagaattt attgatgaag
    54361 aggtctgtta tatacttctt catatagaag gattacttaa atcaataaag aaaactacta
    54421 ctcttgaacc tcttaaaaat gaagaaatta cagagtataa tctatctgaa gcaatagctg
    54481 ttcattgggg aagtatacta aatttaaact taaaggatga tttaatatta ataaagtctc
    54541 ttgctaatca ccttaaatca gttctacaca gaataaacta tggatttact attacaaatc
    54601 ccatattaaa tgatataaag agaacatttc cttatactta taaggctgct aaagagtcta
    54661 atactgttat caaacagttg atgaattatg aagtcaatga tgacgaaata ggatatcttg
    54721 ctttatattt aatatcagca atagatagaa gcaaatctcc cctaaatact attttaatat
    54781 gtcactgtag tgatggtgta tctaatttat tagtccaaaa gttaagtttt gaatttaatc
    54841 agattaatat agttaaatct atacctctat cttctatttc atttacgaac tttgatgatg
    54901 tggacttaat actaaccact gctcctgtag actttgaaca taatgctgaa ctgataaata
    54961 taaatgctct tttaagtaag aatgatattt ccagacttag tacaattata aaaaaactat
    55021 attctgaaaa aaataaaata ttatcttata aataaacaaa aataggcttg tctcaacata
    55081 gagataaacc tatttttcat tgtccaaatg ataaaaatat atttgatttc atagaaaaag
    55141 tgcctcatga actaaaaaat tcattttgag acaccttcat tttttatatt taatcttttt
    55201 atttaagctt ttatattttt taaactttta tattttttaa acttttatat ttaaagtaaa
    55261 ttttattatt tttattgagc gcaagcatta tttatattat taatttcttc agtattctta
    55321 ccaaactttg tagttacaaa tcctattgtt tttattatga gtaataagga tatcaatgaa
    55381 tatatagata tcataaaatt cttacttatt attccagatg ctactattat aaatccatct
    55441 agcataaata atataactgg caacttcaga aacttaatta ccttattaat aagcattgca
    55501 actaaatcag ttccaccagt actacagccc cttattattg ctatccctat agcagttcct
    55561 accaataacc cacctatcac tcctgctact aatagattgt cagttatgtg agtttgtggt
    55621 attactttta agaataatgg acccataaga gttatatata atgtttttat tccaaaacct
    55681 ttccctaaaa ataataatcc cattactaaa agtggcatag atattcctaa tgatatattc
    55741 tcaacaggca ttgataagaa tgtgctaagt acgactgata atcctgttat ccctcctgga
    55801 gctaatgtat gttctgcaaa gaaaaaatta actgctaatg ccattaaaaa tgctgatatt
    55861 gttatcagta aataatcttt tatcatttct tttttcattt aataacctcc tatgattata
    55921 ttgtttcagt ataaaaaatc aattaaatta gtctagcttc ctgtagtttt tcataaaatt
    55981 aatgcttcct taaaacatta agaaagcatc tcttttatca tagtttatta tcttattcta
    56041 aaccaaactt tgtagctgct tcatctatag cttttctaca attcttaaca cctgctgtta
    56101 taccatcttt atccttgaat attgctgaag ataatattac aacgtctgga ttacattcta
    56161 ttaatggctc catattgtct gctcttagtc caccatctat tgctaattca cacttaggat
    56221 tcttttcgtc tatcattttt ctagctcttt ttactaaatc aacagcactc tttctccatc
    56281 cccagttatc ttttccatca gtttcatcaa caccatgaac gactatttgc aatctatcta
    56341 tatcatatat agcttcatca acaaaacata gtggtgtgta acatccaatt gttaatccta
    56401 ctttcatacc aaattctcta cagtaattta ttatgtatgc aagaggagcg cctaaaaaat
    56461 gttctgctgg tattatcaac aagttacatc ctgctgctgc tattttttct ataaataatc
    56521 tatcacaatc tcttgtgtat atatggcatt ctattggttt atctgtcact ggtcttattg
    56581 cttctattat ttgatgacca cccataagtt gcatattttt taagtcatgc atatctgctg
    56641 catctgaatg tacgtagtct acacctgcat ccattgcttc tttaactacg gctgatatat
    56701 gaccgtaatt tacatgtgct aatcctgctg ctatttttat gtgtttcata tttgtatacc
    56761 tccatatttt actttaatta gtattaaata ttagtttttg atatttttta atccagtatt
    56821 acttttattt agcattactt ttattgctgt atatatttct tttatgaact tattctgctt
    56881 ttgttaactg tgaacttatt ttgctttgta aattaatatt acactgatat attttttttc
    56941 acaacacttt gactactcct taaaagtacc tttatattgt ggtaaattat agacattaat
    57001 tgtatataaa aagttagttt tttaccacat tcttatggca tttattgtct atactaactc
    57061 aattgatata gctagttcat ttaatatata atcagactat aaatataaat ttactcgata
    57121 aaaagtacca ttcataacaa tattaatgaa agggagatgt aaaatgagaa actgtattat
    57181 tgcccaatct ggaggcccta cagctgttat caatgcttct gcagttggta tttatgaaaa
    57241 aaatttagaa actaaatact ttgataaagt atattttggt atcaatggga ttgaaggtat
    57301 attaaacaaa aatataatag attcagactc cttaaacaaa gataatgtat taaatttaaa
    57361 gcaaacacct tcgtctggtc ttggttcttg tagatacaaa ctggctgatt ataaaataaa
    57421 ttcttatgat tatgatagag ttataaatat actagatgaa tatgaaatag atacattatt
    57481 ttatataggc ggaaatgatt ctatggacac agtgatgaaa ttttctcaat actgcaaaaa
    57541 cactacttgt aaaataaaat ttatagggat tcctaaaaca atagataatg atttattagg
    57601 aactgacaac tgtcctggat ttggttctgc tgcaaagctt atttctacac taataatgga
    57661 aacatactta gatttttcta tatacaaaaa taatggtata tttatagtag aaaccatggg
    57721 tagagatact ggatggttag cagcttcttc ttcactagct agacttaatg atactccact
    57781 tgttgattta atataccttc cagaaattga tttctatgaa gataagttta tagaagatgt
    57841 tagaaaaata tttaaagaaa aaaataaggc ttatatagtt gcatcagaag gtataaggga
    57901 taaatacggg aactttatat gcgaacaaaa aacttctgct catgataaat ttggtcattc
    57961 ccaattaggt ggagtaagca actatctaaa gaatcttata gtatcatcat caattacaac
    58021 aagagtaaaa accttagaac ttggtgtaat acaaagatgt gctatgcatt tagcttcaga
    58081 tactgattta aaacaagcag ctgaagttgg tgcatatggg atagaactat ctaaaaaagg
    58141 atatacagga gttatggcta tcattaatag aacatgcaat aatccttata agtatgaagt
    58201 tagtcatact gatatttcta aaatagctaa caagacaaaa tattttccta aagagtggat
    58261 aaatgaagaa tgtaattata taactgatga agccctaaat tatctatatc cacttattca
    58321 aggtaaacca gatatcaaat ataaaaatgg actaccttat ttttcaatta tttactagga
    58381 aattattata atttgatata cactcaattc tatcgctctt aaatacctaa gtggctgtta
    58441 aataaaatta taaattgtta tatgacagtc acttaatcgt ttaattattt aactgtttag
    58501 ttttttaatt ttttaatctt ttttaatact aatacgattt gttgtaataa tatctcacac
    58561 ccattttcat tttggataga ttataattag ttagacaata aatattttgt catgatatta
    58621 ttatatatag tgatacaaat agaaatactt ttatcatgac tagaaaaaca aagattacac
    58681 aaaggattta aaaatcaaac aacttcaatt aaaataaatg gttaaaataa cttctaaatc
    58741 aactacataa acaataaaag aacataaagt agttaaatct acaattataa aattggtaag
    58801 actataataa cttaaataaa attaaagtta acaaagacta ttaaagttag caaatattcc
    58861 tctacctaaa taattgcttt ttataaagag ttatttattt taatttattt taattgaaat
    58921 acgattttaa ctagaacaat agattaatgt aatatttaat ataaaataat tataataatt
    58981 gaaaaggaag taatctatga tgaaaatagc agtcataaca accgaatttt taaaagagtt
    59041 tgtagataat tctataaaaa agttaaatat taatgcagaa attgaaatat atatctatag
    59101 agatttttct catgttggag atttatattt agaaatagaa gataggtttg atggatttgc
    59161 agttagtggc cccatcccca aaaaagctat tacaaaaaag gctggaacta ttaaaaaacc
    59221 t
//
LOCUS       DAMJYN010000011        58710 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.011, whole genome shotgun sequence.
ACCESSION   DAMJYN010000011 DAMJYN010000000
VERSION     DAMJYN010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 58710)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 58710)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..58710
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.011"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            86..1282
                     /locus_tag="PC466_000792"
     CDS             86..1282
                     /locus_tag="PC466_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HDF2768214.1"
                     /translation="MKILVLNCGSSSLKYQLIDMNNEEVLCIGLVERIGIEGSILKHE
                     KAGRDDKYVVEQPMKDHKDAIALVLEAVAHPEFGAVKEMKEIDAVGHRVVHAGEKFAT
                     SVVITPEVEEALKECIDLAPLHNPANIMGIDACKAILPDVPMVGVFDTAFHQTMPKSS
                     YLYGLPHELYTKYGVRRYGFHGTSHNYVSQRAAEILGKDIKDLKIVTCHLGNGASIAA
                     VDGGKCVDTSMGFTPLEGLIMGTRCGDIDPAILPFLMRKEGLDADGLDKLMNKESGVY
                     GMTGISSDFRDIEDAAKNGDERAQATLEAYVKKVQKYIGAYAAEMNGLDVVVFTAGVG
                     ENGKAIRADIASNMEFLGMKLDKEANDVRGKETVISTADSKVKMLLIPTNEELMIARD
                     TLRLVK"
     gene            1375..1899
                     /locus_tag="PC466_000793"
     CDS             1375..1899
                     /locus_tag="PC466_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HDF2768215.1"
                     /translation="MKVSIEKINRKETDKIDLNFCEKIDTISYCDEIYKLVSPVNLKG
                     KVSKTNKGLYLDIDVNFTIVDTCSRCLKEVEIPLEYSIQGFLVKEEDYDEDEFEEFDP
                     FIFDGEEIDLIDIIEQTLDFNVPHKVLCSENCKGLCQVCGANLNEEECSCSEITNDEE
                     YIDPRFAKLKDLFN"
     gene            1924..2100
                     /gene="rpmF"
                     /locus_tag="PC466_000794"
     CDS             1924..2100
                     /gene="rpmF"
                     /locus_tag="PC466_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HDF2768216.1"
                     /translation="MAVPKRKTSKSNTKMRRAANSKMEATGFVSCPQCHEPKLPHRVC
                     PDCGYYKGKEVVSK"
     gene            2307..2864
                     /gene="fapR"
                     /locus_tag="PC466_000795"
     CDS             2307..2864
                     /gene="fapR"
                     /locus_tag="PC466_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription factor FapR"
                     /protein_id="HDF2768217.1"
                     /translation="MKKKSKAQRQKELIDMLKTDPFYTDEELSSLFDVSIQTIRLDRM
                     SLNIPELRERVKSIAETQSSKVKTLGVKEITGEIIDLSVGRLGISMLEVTQDMIYSKT
                     NTLKDTYIFSLADSLAMAIIDAPKVIMRVANVKSFKLIEQQDRLIAKAEVYRNIDKKH
                     YVKVVINNKAQEQIFRGKFIFEELD"
     gene            2875..3897
                     /gene="plsX"
                     /locus_tag="PC466_000796"
     CDS             2875..3897
                     /gene="plsX"
                     /locus_tag="PC466_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HDF2768218.1"
                     /translation="MKIVIDGMGGDNAPKSNVEGAVNAIKEYQVDLIITGDKDLLEKE
                     FSNYEFDRNKLEIVHTTEIIENEDKPVKAIRSKKDSSMVVALNLVKEGKADAIISAGN
                     TGALLAGGLFVVGRIKGIDRPCLCSAIPNVKRGMTLIADCGANADCKPKNLVEFAAMS
                     NIYSRKVLGLENPKVALANVGLEEGKGNDLVKRSYEEIKKLDLNFIGNVEAREVINAY
                     TDIIICDGFTGNILLKSAEGVALSVMSLIKETFMASTKSKIGALLIKDDLRKLKSFID
                     YSEYGGAPLLGLNGGVIKAHGSSDAKAIKNAINQGIKFSKGKVVEDINQFISKYNEEN
                     KNNEDE"
     gene            3923..4909
                     /locus_tag="PC466_000797"
     CDS             3923..4909
                     /locus_tag="PC466_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HDF2768219.1"
                     /translation="MNTKAGILGVGSYLPEQSYDNFHFEKIMDTSDEWISTRTGIKER
                     RFAKESEATSDLASKAALKAIECAKLNVEDIELIILATITPDMSLPSTACIVQDAIGA
                     VNATAFDISAACSGFVYGVTIAKQFVETGCYKNVLVIGAETCSKFLNYDDRTTAVLFG
                     DGAGAAVIGPVNEGGILSTHMGSDGKGKDCLKVPAGGSRLKASKETVEANLHTIEMAG
                     SDVFKFAVRKMAETSLRALEKANLNTTDIDYLVPHQANIRIIQASSKRLELDMKKVYV
                     NIDKYGNMSAASIPVALDEAYREGKIKKGDNVVLVGFGGGLTWGASVVKWTL"
     gene            5018..5947
                     /gene="fabK"
                     /locus_tag="PC466_000798"
     CDS             5018..5947
                     /gene="fabK"
                     /locus_tag="PC466_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HDF2768220.1"
                     /translation="MNKICKILNIKYPVIQGGMAWVATASLASAVSNAGGLGIIAAGN
                     APKEAIKKEIVECKKLTDKPFGVNVMLMSPFVDDIIDLIIEEKVQVITTGAGNPAKYM
                     DRLKEAGTKVIPVVPTIALAQRMEKLGATAVIAEGTEGGGHIGELTTMVLVPQVADAV
                     NIPVIAAGGIVDGRGIAASFALGASAVQVGTRFICSEECSVHSNYKNLVLKAKDRDAI
                     VTGRSTGHPVRTLKNKLSKEFLKMEQNGATPEELDKKGTGALRFATVDGDIEKGSFMA
                     GQSAAMVKEITPCKEIIEAMVNQAREIMPAIEL"
     gene            5963..6913
                     /gene="fabD"
                     /locus_tag="PC466_000799"
     CDS             5963..6913
                     /gene="fabD"
                     /locus_tag="PC466_000799"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HDF2768221.1"
                     /translation="MGKVALVFPGQGAQYVGMAKDLYENNAVAKSVIDEASDALNMDL
                     KNLMFNGNEEELSKTENTQPAMVTHSVAVLKAVQAQIDLKYNACLGLSLGEYSALVAA
                     DAIDFKDAVCLVKKRGKFMQETVPAGVGAMAAILGLDRNVLENVVKDIQGGIVEVANY
                     NSPGQIVISGENEKIEEAMVKCKEAGAKRAVKLNVSGPFHSSMLKEAGVKLASELEKV
                     NITKPKVDVVANVNADYYKNEGKDLLIKQVSSSVLWEDSIEILLNDGYDTFIEMGPGK
                     TLKAFIKKIASNKKANVNIYNIDGIDSLNEFVQNYRNGEI"
     gene            6913..7662
                     /gene="fabG"
                     /locus_tag="PC466_000800"
     CDS             6913..7662
                     /gene="fabG"
                     /locus_tag="PC466_000800"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HDF2768222.1"
                     /translation="MINLTGQVAVVTGGSRGIGKEIAKKLASFGADVVINYTSKEDEA
                     LKTKNEIESMGVKCTSIKCDVSKFDEVNQMIDSVVSEFGKIDILVNNAGITKDGLLMR
                     MKEEDFDRVIDINLKGVFNCTKAVTKPMMKKKYGRIINMTSVVGIMGNAGQTNYCASK
                     AGVIGFTKASARELASRNININAVAPGFIETDMTRVLSDDVKESTLANIPKKSYGKPE
                     DVANAVAFLVSDMSSYITGQVINVDGGMVMQ"
     gene            7716..7940
                     /gene="acpP"
                     /locus_tag="PC466_000801"
     CDS             7716..7940
                     /gene="acpP"
                     /locus_tag="PC466_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HDF2768223.1"
                     /translation="MFNKVVEIIIEQLGVEDKEITMETSLMKDLEADSLDAVEIIMAL
                     EDEFGIEIPDTEAENFKSIGDIVKYIEANK"
     gene            7969..9207
                     /gene="fabF"
                     /locus_tag="PC466_000802"
     CDS             7969..9207
                     /gene="fabF"
                     /locus_tag="PC466_000802"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HDF2768224.1"
                     /translation="MNKRVVITGLGCVTPLGTGKEEFWSNIKSGVSGIDKITNFDAST
                     YQTQIAGEVKNFHPEEYISKKELKRLDKFAQFAIVSAKLAVEDANLDLDKVDRERFGV
                     IIGSGIGGVEAIETQHKILLEKGNKRVSSLFVPMMIGNMAAGQVSIFLGAKGPNTNVC
                     TACASGTHSIGDAFKVIQRGDADIMVAGGSEAAVTGLAFAGFCNMKAMSTRNDDPKTA
                     SRPFDKDRDGFVMGEGAGIVILEDLEHALARGAKIYAEVVGYGLTADAYHMTTPAENG
                     EGAARSMNMALKDGNVPLEEVDYINAHGTSTYYNDLYETMAIKTVFGEKAYDLCVSST
                     KSMTGHLLGASGAIEAVVCAMSIEDSFVPPTINIQEVGEDLDLDYVPNQGKEKNIRYA
                     LSNSLGFGGHNATIVLKKYV"
     gene            9433..11151
                     /locus_tag="PC466_000803"
     CDS             9433..11151
                     /locus_tag="PC466_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HDF2768225.1"
                     /translation="MNFRLPKKRLPKKIIFICIILISIILFIKYDQNGLKEREIINKG
                     KYMSESLVADKEYDEAKKVVKTSFESIPEKKYNKVYNEVWDMLKTISYVPDGTKIVID
                     SLEKMRESDVKLSDECRFNIEKRLASVYIMDNNYSKAVDLTVKSIKLAEKLGNNYEKA
                     RLDVDLASIFLNIGSYETGEKLIKDSFKIDIDEGEKNGMVRLYAIINLAEIYVEEGEY
                     DKAIEISSRIKDYKKFVNTDNYNDFDIMASIMKSNAYVGKNNIQKAKTFLEKADYLIK
                     SDRTVYILDKDMYYYMAMGNLEYKSENYNSAIDNYKKSLEISTKRKLTQEKIKNLNKI
                     LNIYEKQGNIESLNEYQKMLINEYKENKSIRDSETSFYIIDKVSNESKLFEKTKKEIK
                     YYKILFTVILIAILGSTFLYNRLKYFKAQNLHDGLTNVYNRKSFDIMYEKYREKDDNF
                     ALVMIDIDNFKLINDNYGHKFGDTVIKGITNTICVMLEQDDKVFRYGGEEFSVLIRNK
                     SGEEVADIIDNIRVAIANKKWNDDVTVTISAGVAHISDSKDVLEEADKNLYKAKQLGR
                     NKVVYK"
     gene            11182..13182
                     /locus_tag="PC466_000804"
     CDS             11182..13182
                     /locus_tag="PC466_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2768226.1"
                     /translation="MKQSIAIVTDKITKLSSFLEENIRLVLGNYIDINHYYLEVLKEN
                     DKIQGDFVLVMNDDRLNSMRKHLVQDSKIIVIRRTLKENEIYGLFSIPNGTEVLVVND
                     TKETTLETISLFYKIGVKNLKFTPYIEGKIYKNIDIAITPGVKEKVPSYINKVIDLGN
                     RYIDISTFIEIINGLRIDVKEIRKNLMAYSESLISLDNGVKDNYRQLFLKIEEQDVIL
                     NLSKDGIIFTSADGIINTFNKEALKILGINENPQGKNIEDIISEDLNILLEDKEIIDE
                     VVFTNKKYINVNKKSIFSMGNKAGIYYNLQEITYIKKLEQNLTNKLREQGQIARYTFK
                     DIKTKNKNMVKCVELAKKISKSDLSVLIIGESGTGKELLSQSIHNASNRSNQPFIAVN
                     CAAVPDSLLESQLFGYEKGSFTGALREGKKGLFELANNGTIFLDEIGDMPPLLQTKLL
                     RVLQEKQVMPIGSHNVINIDVRVIAATNKNLLKMIREGKFREDLYYRLNVLPIDVPSL
                     RNRKEDIITLMNFFLKNNVRLSPEVITILEKYNWPGNIRELQNVASYVSLMCDSMVFR
                     DDLPPYIRVECANNYEDGFGYTKKEFEEILRILYERRESSSGVGRGFIIEKLIQEGIE
                     ISESKVRKVLSYLSECGYISSKSGRGGSQITSEGIKLYNNIN"
     gene            13530..13775
                     /locus_tag="PC466_000805"
     CDS             13530..13775
                     /locus_tag="PC466_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03905 family TSCPD domain-containing
                     protein"
                     /protein_id="HDF2768227.1"
                     /translation="MKYKTTGTCATEIEFEVKENKVTNVNFIGGCDGNLKGLKVLVEG
                     MNIEDVIQKLKGIECKTKPTSCPDQLSLALENYMNIK"
     gene            13810..14535
                     /locus_tag="PC466_000806"
     CDS             13810..14535
                     /locus_tag="PC466_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HDF2768228.1"
                     /translation="MKPIIGILGNLIIMENGMFPGLERSYVNNDYINAVLKGGGSPVI
                     IPVNTDKEVIKKQIEMVDGVLISGGWDINPQLYGEETREETTFIYPEVDEFDLIAISI
                     ALELKKPILGVCRGLQILNVSLGGTLYQDNNLIEGSYIKHTQSSKRHVATHKVDVKEG
                     SILEGILGKQLLTNSYHHQSVNQLGKGLKAIAYSKDGIIEAIEKEEENFVVGVQWHPE
                     MMVDYCDKMEKLFKYFINICSNL"
     gene            14557..15870
                     /locus_tag="PC466_000807"
     CDS             14557..15870
                     /locus_tag="PC466_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDF2768229.1"
                     /translation="MNEKNKMGLISIILLGINAVVGAGVFLLPGDAMKSFGVASIFVY
                     IFDMLLVLSMAFCFAEVAGKFNKNGAAYVYTKEAFGDFCGFEVGLMKWVIGCISWGAL
                     IVGFPTSLSAVWAPAGEPHIQKIIIVAMIVGLTIINLLGVSLSKIVQNVITVGKLIPL
                     ILFIGIGIFFIKGVNFTSSTMVPPGAGATEFGAAALLMFYSFTGFESIAVAAEDMENP
                     QKNIPIAIISVIVIASIIYILNQVVCVGILGDSLSSTSTPVADAARICFGNMGAGLVT
                     FGTLVSVGGICMCGAFVNPRSCVALADDKMLPRIFARKDKKGTPYVAIIATMLITIPI
                     ALSGSFAELAAISAVARFIQYIPTSLSVLVFRKKRPELVGTFKTPFGAVIPLIAVCVG
                     TWLLFQASMHQLIMGLGALAIGVPLYFIMKSYNRKVCGENLKKIV"
     gene            16169..16615
                     /locus_tag="PC466_000808"
     CDS             16169..16615
                     /locus_tag="PC466_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2768230.1"
                     /translation="MGGETHFLSFGKDEYKISLEEQENAIESAKASDNSVKLIAFIDD
                     EIVGIATIDSNQKAKGKHVGVLGIVVKEKYWGIGLGKRLMLDLIEWCKSNGITKKITL
                     VTNEENYNAIGLYKKVGFEVESILKKECYYNGVYTDLIGMSLLLGI"
     gene            16704..18689
                     /locus_tag="PC466_000809"
     CDS             16704..18689
                     /locus_tag="PC466_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphatase class III"
                     /protein_id="HDF2768231.1"
                     /translation="MKNLCKISDDYLNSKLKYLKLLSKQYPSISKASTEIINLEAILN
                     LPKGTEHFITDVHGEYEPFVHVLKNGSGVIKRKIEELFSNTIRDSEKKMLATLVYYPE
                     QKLDLIIKQEENIDDFYRINIYRLIELCKYASSKYTRSKVRKLLPENFKYIIEELLHE
                     HVKSEHKEEYYKSIVETIVDIGIAKEFIIAISTVIQKLVVDRLHVIGDIYDRGPRPDI
                     IVDKLIEHHCVDIQWGNHDILWMGAASGEKTCIANALRISARYANLDIVEDIYGINLL
                     PLATFAIEMYKDDPCKEFIPKVNDQSVTTTEKSLMAKMHKAISIIQFKLEGEVIRRRP
                     EFEMEHRLLLNMINYDEGTITLKGKTYKLKDTYLPTIDKKDPYKLTMEERNVIDKLVS
                     SFRGSEKLQKHVSFLFSKGSIYLKANSNLLIHGCVPLNEDGSFMSMNIMGKEYKGKAL
                     MDKMESLAREGFFFKDKAEEKLYGMDIMWYLWTGKCSSLFGKDDMTTFERYFIEEKET
                     HKENKNPYFKLRENEMACKRLFEEFDLELDESHIINGHVPVESKNGESPIKANGKILV
                     IDGGFSRAYQKTTGIAGYTLIYNSRTLQLVSHEPFNSAEEAIANESDILSTTVVVEHK
                     AKRKMVRDTDEGVKIQEEIEDLKLLLMAYKKGLIKEM"
     gene            18913..19881
                     /gene="spoIIIAA"
                     /locus_tag="PC466_000810"
     CDS             18913..19881
                     /gene="spoIIIAA"
                     /locus_tag="PC466_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AA"
                     /protein_id="HDF2768232.1"
                     /translation="MNKLSDEIINSLSTTIREKVEKVSNNNLNIEEIRLRSQKPLILN
                     ANSKDYFYNQKTMTLDLNQQNSYVVTREDVEQTFQIICKYSIHSFMDDIKKGFITLRG
                     GHRVGLVGKAIVEDGQVKNIKHISSLNIRVSREIIGCSDKILSHIIKGKNQINNTLII
                     SPPQCGKTTLIRDIVRNLSNGNEDYGFKGLKVALVDERNEIAGAYLGVPQMDVGIRTD
                     IIETCPKDLGITMLLRSMSPNVIVTDEIGSEKEIKALYTALNGGIGLITTVHGDSIDD
                     IQNRKELNRLLDKELFKKVIILSAKRGAGTIEKIYDLEEKRWYFAN"
     gene            19871..20392
                     /locus_tag="PC466_000811"
     CDS             19871..20392
                     /locus_tag="PC466_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AB"
                     /protein_id="HDF2768233.1"
                     /translation="MQIKIIIIALLVGSSYLIGEQIYKTYTRRHKQLNDLIRVLEILR
                     MDLSFGLYTLEEIFNRIGGNKEFCFWKFFYQISEGLHNEQSKTLEIIISENIDVLSKE
                     TYLGNKEIEELKNLILTLGKSDIESQQRMIDLSIENLKKQTYETKEDINKKGVLYKKL
                     VTFIGIGICIILI"
     gene            20409..20606
                     /gene="spoIIIAC"
                     /locus_tag="PC466_000812"
     CDS             20409..20606
                     /gene="spoIIIAC"
                     /locus_tag="PC466_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018589775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AC"
                     /protein_id="HDF2768234.1"
                     /translation="MEISLILKVAGVGILISVLNMILEKTDRKDWAGLTTLAGVIIVL
                     GMVITEISDLFNTVRTMFQLY"
     gene            20622..21008
                     /gene="spoIIIAD"
                     /locus_tag="PC466_000813"
     CDS             20622..21008
                     /gene="spoIIIAD"
                     /locus_tag="PC466_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AD"
                     /protein_id="HDF2768235.1"
                     /translation="MEIMQLIGIAIISTTLCLVIKKDRPEIANFIAIITGVIILLSVM
                     FKLNFIVDSIQDLANKANIPTMYISLIIKLIGIAYLMEFAIQLCKDCGEGNIASKLEF
                     GGKIIVMSMSFPILLSIVEMVVNIIP"
     gene            21093..22298
                     /gene="spoIIIAE"
                     /locus_tag="PC466_000814"
     CDS             21093..22298
                     /gene="spoIIIAE"
                     /locus_tag="PC466_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AE"
                     /protein_id="HDF2768236.1"
                     /translation="MKKRFLPMIIGFLFTFFFVNIFAIMIFANEVPSSEDKEYGETKN
                     SIDKYIDGQLDKLDINEIQDYINKEIVINDVNLKSFVKDLISGEKNILDLFNKDGLKI
                     LMFDEFKASLKVVAVILVLALLSSILKSLENSFSSGAVSQIATYIIFITMVSLTLIGF
                     KDVLQICYDAIDHTVGLMQVIMPILITFLLLIGFPITSTTLNPIFIGGVTFINVFFKN
                     FLFVSITVAFGILIINNLSKNIRLKRFFSFVKQINYVSIGAMFTVYLGLVSIQGLYVT
                     SFDKFSVKTAKFAIGNFIPVVGGFVSDSVDILLSSSQLIKNIFGGIGLILLVGICLLP
                     VIKILSVIVVYKLAAIIVEPVGEDGISNFLNEVANLMIIMLASVIAITVMFFVTVAIL
                     TSISVVSQG"
     gene            22358..22975
                     /locus_tag="PC466_000815"
     CDS             22358..22975
                     /locus_tag="PC466_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AF"
                     /protein_id="HDF2768237.1"
                     /translation="MLEGIKAWIVSVLIGAFIVNIVDMILPSSKIKPYVNLVLNFMFV
                     FIVITPVVGFFSKDMSLEDRILKSMGNYNKQYVDSTNALAKETGNNSLSKGYEDGLKE
                     VLKLKLDEYGYDLEDIELNGANINNIKIKEKNNSAKSNNSSNEENKNNSTKREEENIN
                     SNDKENSKQVFKKGTEYGLNLNEEKLKNDLIKVLDVSIEDIQIDK"
     gene            22987..23541
                     /locus_tag="PC466_000816"
     CDS             22987..23541
                     /locus_tag="PC466_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AG"
                     /protein_id="HDF2768238.1"
                     /translation="MLKNLNDKDKRKVYSLITIAGICVVSLVLLSCFPSSKSDKQVGK
                     TETNKNAEKQVTKKQEKDDLESKLTAILSKIDGAGDVDVMVTFESSEEIQPAFNSNNT
                     TETTEEKDAQGGERTVTTSSENKTMITSNSSDPVVIKTTEPKIKGVIVVASGASDPSV
                     KETLYSAVQTSLQVAGHQVEIYSK"
     gene            23568..24257
                     /locus_tag="PC466_000817"
     CDS             23568..24257
                     /locus_tag="PC466_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpoIIIAH-like family protein"
                     /protein_id="HDF2768239.1"
                     /translation="MKFNYKGRGFVIITLTAMLVVVGTVNYQLSKKSLLETSKEFKAY
                     EEAQLQKNTDDSDSSKTEDSSNVDKQGGKESADIDIVDSKASKVKEKATETSKEIKAQ
                     LSSEKNMKKASYILDMKMNREKQRNELVQDLNEMINNPSTTEESRKEASNMKLNIVKI
                     QEKELQIENLLSTKGYEEALVYISDNKVNVVVNEAKLEKKDAAKIFDLVAEQANVKYE
                     NIKLTNNNSNK"
     gene            24367..24729
                     /locus_tag="PC466_000818"
     CDS             24367..24729
                     /locus_tag="PC466_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HDF2768240.1"
                     /translation="MEDNKFGQVKISNDVIATIAGLAALEVEGIETTATLTDKLLKNN
                     GVKIQIEEEDVNLDVMVTIKYGMSIPDTAFKVQENVKNTVETMTGLKVSQVNIHIQGI
                     SFKKDKVDKEEAKATKKN"
     gene            24814..25320
                     /gene="nusB"
                     /locus_tag="PC466_000819"
     CDS             24814..25320
                     /gene="nusB"
                     /locus_tag="PC466_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HDF2768241.1"
                     /translation="MKKDRAQKSTTREYIMKLIYQININKEDFETLEDKVDNFLKDNS
                     EHIINRYKELALQYSKNTNLKLEDTEIEDVIDKKYINTVCKALKENHDKIDELINKHA
                     KNWTVDRMPKVDVSILRLSVCEILYLDTPNKVSINEAVELAKIYCDDKSPKFINGILG
                     SVVDEIGK"
     gene            25304..26374
                     /locus_tag="PC466_000820"
     CDS             25304..26374
                     /locus_tag="PC466_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-sialoglycoprotein endopeptidase"
                     /protein_id="HDF2768242.1"
                     /translation="MKLGNNIIIGIDTSCYTTSIAAISLDKKVIFNEKIMLEVRDNSK
                     GLRQSEAVFQHINNLGILSDRIKSFKDKFNVEGVCSSKKPRPVENSYMPVFNVGHNFG
                     KLLSSIYGCRFYETTHQENHIEASLLNSKLKNNNKFISVHMSGGTTEILLTSKQDSHH
                     NVCDTNLGKIAKISIKKDDKSKLYNNFGYNIDIIGGSKDISFGQLIDRVGIKLGYKFP
                     SGKYLDENALNCNLKIESGLKTSVRDGYMNLSGLENQVNKIINDNGDNTNQKEYISKL
                     VLDSVVRNMFKSLVYLCETYNVNEVVFAGGVSASKYILRELSMKLRKKHIEAYFTEPQ
                     YSTDNAVGCAIIGLNNFLGERV"
     gene            26371..27576
                     /locus_tag="PC466_000821"
     CDS             26371..27576
                     /locus_tag="PC466_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HDF2768243.1"
                     /translation="MKLRALDISEANSYIKRILINDPILSNLKVKGEISNFKVHSSGN
                     VYLSLKDETSKLNCVIFKSNFNRNLKLDNGVKIIANGYISVYERDGAYQLYINEIEIE
                     GIGNLHIEFNRLKEKLNKEGLFDPKYKIPIPKMPNSIGVITSPTGAVIRDIINVIKRR
                     YPKVNIKLYPVMVQGDKSAEEICEAIRFFNHMKNVDTLIVGRGGGSIEELWSFNDEMV
                     AREVFNSQIPIISAVGHETDFTICDFVSDMRAPTPSAAAEIATPSLDDINYKLGNIKS
                     RMSKSLTNQIELDQYRLETVFNKINNYLDSYTIKDKVIQLDKIYDKIIFGIENNLKLE
                     DEKLVKIGALLHNLSPLATMDRGYSITQKNGKVINSIKGLKIKDSIDIVLKDGNLECM
                     IDKIENKEG"
     gene            27578..27793
                     /gene="xseB"
                     /locus_tag="PC466_000822"
     CDS             27578..27793
                     /gene="xseB"
                     /locus_tag="PC466_000822"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HDF2768244.1"
                     /translation="MNLTYEEAYKRLESILSELESKNASLDESLSLYEEGISLYKHCN
                     KLLDDAKLKISKFNQLGIEEDFKIEEE"
     gene            27796..28683
                     /locus_tag="PC466_000823"
     CDS             27796..28683
                     /locus_tag="PC466_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HDF2768245.1"
                     /translation="MEFKQCLKEKASFVEKVLKEYMPKEEGYQKTVIEAMNYSLSAGG
                     KRLRPILTLEACKIVGGNEDEAIPFAIAIEMIHTYSLIHDDLPALDNDDLRRGRPTNH
                     KVYGEAMGILAGDALLNYAFEVMLAGSINKENPEKYLKAINEIAKGAGIYGMIGGQVV
                     DVESENKQIEKEKLDYIHMNKTAAMMVGCMRAGATIGGANSEQMEEITKYAKNIGLSF
                     QIVDDILDIVGDEAKLGKKVGSDIENHKSTYPSLLGLDKSKEIAHNLIDEAKKSIEKL
                     SDDVDFLKGLAEYIIDREY"
     gene            28713..29150
                     /locus_tag="PC466_000824"
     CDS             28713..29150
                     /locus_tag="PC466_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divergent PAP2 family protein"
                     /protein_id="HDF2768246.1"
                     /translation="MDFFSEIFNNGALGISLIACFLAQFIKIFTGKEKRIELSRILIS
                     GGMPSSHSSFVTSLATVVGIEKGFNSTDFAIITVLALIIMYDAAGVRRAVGKQATILN
                     QMVADIQHGKHIEQKKLKELIGHTPLEVWFGALLGIVTALILM"
     gene            29184..31049
                     /locus_tag="PC466_000825"
     CDS             29184..31049
                     /locus_tag="PC466_000825"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HDF2768247.1"
                     /translation="MYKYLDKVNSPKDIKNMSIEEMDLLAKDIRKFLVKSVSKTGGHL
                     ASNLGVVELTLALHKVFDSPKDKIVWDVGHQSYVHKIVTGRKDCFVSLRQFNGLSGFP
                     KENESPHDIFDTGHSSTSISIATGIACARDIKKENYSVISVIGDGSITGGMALEALNQ
                     LGYIDTNMIVILNDNEMSIDKNVGGMSKYLSSIIRNSTVEKMTDEVDKILNVTQTGEI
                     LSKTAHRFKDKLMYSFSPQDCSFFDSLGIRYYGPIDGHNTKELIDILRKAKHKKGPVL
                     LHVITKKGKGYRFAEEQPDKYHGVSKFDIKTGVTSAKVKSMSISVGEKLVDMANNNED
                     IVAITAAMPSGTGLNLFESAYPKRYYDVGIAEQHATGFAAGLAKNGMKPYFAVYSSFL
                     QRAYDQVIHDVCITKKPVTFLIDRAGLVGNDGETHHGMFDLSYLNSIPNIVVMAPKDT
                     REMELMMDLSLKLDCPLAIRYPRGSSYYLDKGEYGEIVLGKYEVLDDGQDTVILCIGS
                     MVKHALEAKEILSREGINPTIVNARFLKPIDEGMLKALLKNHKNVVTIEDNIVTGGFG
                     SRINKFIIDNEYNVNILNIAIPEEFVKHGNIDELYDFVGLSPKSIADKIRKLVIE"
     gene            31182..31994
                     /locus_tag="PC466_000826"
     CDS             31182..31994
                     /locus_tag="PC466_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HDF2768248.1"
                     /translation="MKKRIDLLLVEQGYFESRERAKKAIMAGLVFVDNQRCDKAGTEV
                     KEDCSIEVKGNPIPYVSRGGLKLEKAMKNFDLTIDGKVCMDIGASTGGFTDCMLKNGA
                     IKVFSIDVGYGQLAWKLRQDDRVVCMERTNIRNVTIEYTKQFADFASIDVSFISLKLV
                     LPKAKELVRHDGEVVALIKPQFEAGREKVGKKGVVREKSTHIEVIKMISDFSVENGFE
                     ILGLDFSPIKGPEGNIEYLIHLRNGNEGYEFDGETYNNKIVEVVEASHNLDK"
     gene            32014..33693
                     /gene="recN"
                     /locus_tag="PC466_000827"
     CDS             32014..33693
                     /gene="recN"
                     /locus_tag="PC466_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HDF2768249.1"
                     /translation="MILELYMKNCALVEELRLNIDKNLNILTGETGSGKSIIIDALGL
                     CLGDKYDRSFLRKGTDKGLVEAVFFSDNRYLKKILEENDISMEDDNLLVITRLIYSDG
                     KSTARVNGRTVKVSLLKEIASTLIDIHGQHQNQALFNKDTHLKFLDLFGENELEEFKI
                     AYKNVYHKYSEVKKALNCLTENKDEMQIQREIDLLRFQINEIEAANLNKNEYEDLLKQ
                     REVYRNSEKIYNNLNSSYSKLHNGEYNVIDLIGLASKELNDISKYDSVLSEYSDTVER
                     IMYELQDISGEIRNYKDNIDFEPYELEQIELRIDEINNLRRKYGDSIDDIFEYYGKIK
                     DRLDEILNRDERVEQLKSKLMNIEEDLKIKASKLTKARIEVATTLEKILLDELKSLNM
                     KNVMFKVNFEKGSFTLDGVDDIEFMISFNLGEDIKPIYKVASGGEMSRFMLAFKTILA
                     DIDDIDTLVFDEIDTGISGIAAQIVGEKLSDIAKKKQIICITHLPQIAANADTHYCIE
                     KDTSNNRTFTNVSKLNESQRKNEIARLIAGNNITEKTIEHASEIIELAKKC"
     gene            33908..34774
                     /locus_tag="PC466_000828"
     CDS             33908..34774
                     /locus_tag="PC466_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768250.1"
                     /translation="MNKKDTMHLIFIIVIFILLWYIVVAVSEINKNIESCSNKLDYLS
                     QELMSTKSDISNTINEEMSKSYITKSIDLKVKKIEKKECTIDVDVQLSKLGKNGKVFF
                     MYKEDSDKWNETEMTKHGELSYACEIKINTGSEYDYKVVTSGDISESSDVQKLTKSDY
                     MPEQPIFNSGIRDNREYFIEIVENSNLFNHESEKSKNKAYDNIRLEKVDIIVNEGKKD
                     TIYKAQLAEGLDDGKTNNSNRNQVNYEVSFPKRDIDDIIYIKAKLTYNNGVEYTKDIT
                     EDITMGLQDLEK"
     gene            complement(34865..35356)
                     /locus_tag="PC466_000829"
     CDS             complement(34865..35356)
                     /locus_tag="PC466_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2768251.1"
                     /translation="MADKMAQNITLQFVEEKDLENLENVKLLFTEYSNSLNIDLCFQD
                     FNNELKTLPGKYKKPSGSLILAFVDENLAGCVALKKLEGKICELKRLYVRNQFRGLKI
                     GKILLEEIIVEAKKIGYTHMRLDTLPSMKSAQGLYEKFGFYDIELYTYNPIEGARYME
                     LKL"
     gene            complement(35417..35857)
                     /locus_tag="PC466_000830"
     CDS             complement(35417..35857)
                     /locus_tag="PC466_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2768252.1"
                     /translation="MKLNVRIADINNWHDLVSLSVDKSQLDYIESNALSIAESKFITA
                     WVPVGIYDENSLIGFAMYGRLEDDRVWLDRFMIDSKYQGKGCGKASLDFLVNHLKNEY
                     NCDELYLSIFEDNKMAIKLYKDFGFKFNGELDYGGEKVMVLKSN"
     gene            36018..37076
                     /locus_tag="PC466_000831"
     CDS             36018..37076
                     /locus_tag="PC466_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HDF2768253.1"
                     /translation="MNKINKNFKNIWIILGAVSIFTMVIIFNKNCNVNKETQIEAFTI
                     KNHDKKFVYPMGNIIGVKANTDGVLVLGYEEEDVGYIGGIQIGDNIVKIDNKRIKNSQ
                     DVSEILNKIKKSKVEVTFERKNKYKTEVIETKKENGKYKLGLWVRDKISGIGTMTFYD
                     PSMEKFKAIGHAIKDSDTNELLKIKQGYIYKPEQLKIVKASNEKVGKIKGDFNDSNLM
                     GNFSNNSELGISGNITENHNKEFNVANKEKQLIEVGRPQDVKIGDAVILFEDKNKNIT
                     SYDIKIESIVYDKGNYRDMVIKVVDDKLLEYTGGIVQGMSGAPIIQNNKIIGAITHVF
                     RDNPKKGYGIFIDEMIKL"
     gene            37218..38042
                     /gene="spo0A"
                     /locus_tag="PC466_000832"
     CDS             37218..38042
                     /gene="spo0A"
                     /locus_tag="PC466_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation transcription factor Spo0A"
                     /protein_id="HDF2768254.1"
                     /translation="MGGFLVEKIKIVLADDNKDFCQVLKEYLSNEDDIDILGIAKDGI
                     EALDLVKKTQPDLLILDVIMPHLDGLGVIEKLNTMDIPKMPKIIVLSAVGQDKITQSA
                     INLGADYYIVKPFDFVVFINRIRELVSNRVTQVEPKPRPVQETQMTRSDFVKNVGNIE
                     TEITNIIHEIGVPAHIKGYLYLREAIKMVIDNVELLGAVTKELYPSIAKKFNTTPSRV
                     ERAIRHAIEVAWSRGKVDTINQLFGYTVHNTKGKPTNSEFIAMIADKLRLEHSMVK"
     gene            38455..39576
                     /locus_tag="PC466_000833"
     CDS             38455..39576
                     /locus_tag="PC466_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768255.1"
                     /translation="MRVEAPIKVDRKTKKLAKRVESGEIAVINHIDIDEVAANSLVEA
                     KIKLVINAAPSISGRYPNKGPGILTENNILIIDNVGEELFEELKEGETIEVVDGKIYR
                     KGKFLGAGEVLDKYEVSHQIKAAYENLAVELDRFIDNTIDYAKKEKGFILGEVEIPKV
                     KTNYANKHVLIVVRGQDYKEDLSTMLSYIEEVKPVLVGVDGGADALIEFGYTPDVIVG
                     DMDSVSDEALKKASEIVVHAYTDGRAPGLKRVEELGLDAVVFPAPGTSEDIAMLIAYE
                     YKAELIVAVGTHSNMIDFLEKGRKGMASTFLVRLKIGSKLIDAKGVNLLYRSKLKIKY
                     IWALIATALFPVLVVASLSPGVQQFIQLMQLKFRVLLQM"
     gene            39594..40469
                     /locus_tag="PC466_000834"
     CDS             39594..40469
                     /locus_tag="PC466_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper transporter"
                     /protein_id="HDF2768256.1"
                     /translation="MHINMKYYIVTIGAIFIALGIGMLVGFNLNNNQQLSEQQANIIN
                     DLDDKFNILKEKNDKLDSDLASVNRDYEEAVNFINKNVDKILAGSLNGKSIGIISANE
                     NDDYTKNIEDIINKSNGSIAFNIVLKENITNPEKLKEMSTKLGTDVKNANDAVNYIID
                     TLKKEDASDILTYLQELDVIKFNSLGNTYLKYDSVVIAGGNDAKDSTKQFEKIEKFVV
                     SKLKSENKYLVEVQNTGVKTSYVELYSKNKVATIDNIDEGIGSISLAILLQQGNIVGN
                     FGRLDTATSLLPSIK"
     gene            40493..41185
                     /locus_tag="PC466_000835"
     CDS             40493..41185
                     /locus_tag="PC466_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDF2768257.1"
                     /translation="MDSYISIIIPAYNEESRIKYTLESILDIKQINEIIVVDDGSIDN
                     TAKVVSELENEKIKFFKLDKNRGKGYALNYGIKLAMKNADIIGFLDGDLGSSAKEVEK
                     LIVPILNGEADVTIAKFPPAKRKGGLGFVKGLAKNSVFEMTGVELDATLSGQRIFKRE
                     VLEKFDEIPFGYGVEVGMTIDILKYGFKIKEVLVNMTHNETGRNLKGFIHRGKQYYHI
                     KKVLGQKKKEWR"
     gene            41193..42017
                     /locus_tag="PC466_000836"
     CDS             41193..42017
                     /locus_tag="PC466_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HDF2768258.1"
                     /translation="MKDYILYTILLLTGLFGTYAVIPLFKNLLINGNVLRPNYKKDMI
                     PVSMGIVFLPMIVINGIILAFFTTEFKDLAYIFMFMFGMISMFFAGILDDVIGNRDVS
                     GLKGHFKSLFKGSLTTGGFKALFGGFVGLIVSVAISKDIIDIIVNTLIIALSTNLMNL
                     LDLRPGRAIKAYLFIMVIIFLTLTGFVQVLPLLIVPNVLAYFNYDLKARAMMGDTGSN
                     VLGISIGMLISFGYPFNIRLGWLIFVVIMHIFTEKYSLTKIIEKNKLLNFIDKLGR"
     gene            42022..43089
                     /locus_tag="PC466_000837"
     CDS             42022..43089
                     /locus_tag="PC466_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3866 family protein"
                     /protein_id="HDF2768259.1"
                     /translation="MISKRVGIVESIVSQTETLDDIRVNINGKIQRAYNYPKISGTIN
                     IGDEVVLNTTAVELSLGTGGYHFVITNLNNIESTLTEGGHIMKLRYTPLQIKVDSVEE
                     QESIYHDKFANFKGLEGLSVVVGTLHSMLTPFAASFKRNNPNKKLVYIMTDGASLPIY
                     LSKNVDTLKEKKLIDSTITIGNAFGGDYECINIYTALITAKEILKADAVFVSMGPGIA
                     GTGTKYGFTGIEQGSILDAVKKLEGRAIAIPRISFADKRERHQGISHHSMTVFKEIVN
                     VNVDIPITIYDDEKLNFIKEQINLNGLDKKHNIIYIDNNKTKEDLDYFNLKVKSMGRN
                     YEQDEAFFKAASTAAYYLMEV"
     gene            43091..43627
                     /locus_tag="PC466_000838"
     CDS             43091..43627
                     /locus_tag="PC466_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HDF2768260.1"
                     /translation="MVLEEKTISSDRVYTGKVITLKVDTVEIPGQGYQKRELVEVGGA
                     VGIVAITDDNKVVLVKQFRKPIEKPIFEIPAGKLEKNESPKECAERELKEETGYSAKN
                     IKLIHKFFTSAGFSNEIMFVYLATGLTPGENNLDADEFLDVYEIELEEAYNMVLKNDV
                     EDAKTSIGLLLVKDMFKN"
     gene            43695..44300
                     /locus_tag="PC466_000839"
     CDS             43695..44300
                     /locus_tag="PC466_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein M"
                     /protein_id="HDF2768261.1"
                     /translation="MRRTYRKNDFRELNRQIIIIGLLFMMSIVVGSYINKILPGSSNN
                     ILNNINPAVEYYNLNISIKDTVIQNLKSDAIFMGSIALLSLFVVTIPAVLVAFVLKGM
                     SIGYTINSCILALKFKSIKMILIILFKNLIIIPCAIILALISLSYFKEMVYEFKKKNR
                     KNMQFLIKRYILNIIIIIALSLGLQLILNTVSIGIIKFLAK"
     gene            44312..45226
                     /locus_tag="PC466_000840"
     CDS             44312..45226
                     /locus_tag="PC466_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDF2768262.1"
                     /translation="MDIIEGYIDYIKDKKKLSENTVASYFMDIKKYMEYINQKSIKLV
                     DIVENDIISYLIKLEKDNVSIATIARMISSIKSFHDYLFLNHICTNNPAKDIKKPKIK
                     KENINILTEEEIERLLNFPKLTTPKLIRDKAIFEVLYGTGIKVSELVEMNIEDIDLDI
                     DYIYCNSCCKNQRVIPLCDITKLYLEKYLKEARPKMAVEGEKSLFVSSLGQRFTRQGL
                     WKVIKKYSNLANIDKNINPTMLRHSFAIHLLNEGANIAVVSKILGNVNLSSLQVYLNH
                     IDKNVRREIKEKHPRNDVDVELQKAEAK"
     gene            45268..46440
                     /locus_tag="PC466_000841"
     CDS             45268..46440
                     /locus_tag="PC466_000841"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HDF2768263.1"
                     /translation="MSRVIWIVIDSVGIGALPDAEKFGDSKDVSTLGNIFKEYPDIQI
                     PNMRNLGIGNIDGIDFFESIKEPIGCFGKCKEMSQGKDTTTGHWEMTGIIVDKPFKTF
                     EHGFSKEIIEEFEKKTGRKVVGNKPASGTVIIDEYGEHQIKTGDVIVYTSADSVFQIA
                     ANEEVIPLEELYNMCKIAREIMMGDNAVARVIARPFIGKKKGEFVRTSNRRDYSLDPF
                     EPTVLDNIKESGLDVLAVGKIEDIFNGKGITDAIHTKSNMDGVDETLNYMKQDNKGLI
                     YSNLVDFDSKYGHRRDPEGYKKALEEFDSRLPEIMANMREDDILIINADHGNDPTYKG
                     TDHTREYIPVMIYGNKIKKGFNLGVKDTFADIGATVADILNVKLPKHGSSFKEDLF"
     gene            46487..47299
                     /locus_tag="PC466_000842"
     CDS             46487..47299
                     /locus_tag="PC466_000842"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HDF2768264.1"
                     /translation="MFEKIAQSSKFINSKSNIKPKIGLILGSGLGDLANDIEDPVTIK
                     YSEIPNFPVSTVAGHAGQLVIGKLEGKEVIAMQGRFHYYEGYSQKEATFPVRVMKELG
                     VEILIVTNAAGGVNKEFKAGDLMLIRDHINFSGSNPLVGKNDDRFGARFPDMSDAYSS
                     KYVDVVKNCAKECNIDVKEGVYMFFSGPNYETPAEVRMAQILGADAVGMSTVPEVIVA
                     SHSNIGVIGISCITNMAAGILNQPLSHEEVIETTQKVKSEFMNLVKTTVKNL"
     gene            47503..48828
                     /locus_tag="PC466_000843"
     CDS             47503..48828
                     /locus_tag="PC466_000843"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HDF2768265.1"
                     /translation="MRMYDIIKKKRDNLELSKKEINYFIENYSKGDIPDYQASALLMS
                     IYLNKMNKQETVHLTEAMMNSGDMINLSEVDGIKVDKHSTGGVGDKTTIALIPLVASC
                     GAPVAKMSGRGLGHTGGTIDKLESIPGFSTEMEISKFIDSVNKSKIAVCGQSAKVAIA
                     DKKIYALRDVTATVDNISLISSSVMSKKLASGADAIVLDVKTGDGAFMKTLEESFELA
                     KSMVDIGTGMNRDTIGIVTDMDEPLGFAVGNSLEVIEAIETLKGNGPKDLVELCEVLG
                     AYMLVLSKVAHDFEDGVEKIRESIKSGTAIQKLKEFIENQGGNKDVVDDYSLFKKSKY
                     KYPVKSIKSGYISKIKAEDVGVSAMILGAGRETKDDILDLSAGIILEKKVGDYVNEGE
                     VLAYMYYNDEQKLSLAKGRFIDSYSIVDSKIEKNKLIYGIVTKEEIKKF"
     gene            49041..50120
                     /gene="mltG"
                     /locus_tag="PC466_000844"
     CDS             49041..50120
                     /gene="mltG"
                     /locus_tag="PC466_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HDF2768266.1"
                     /translation="MNFKENRLKIAVLIIVILIILAGIFVFIQIGPYDKNNKKDVIID
                     VPSGASVGKISDILYENKLIKNELLFKLLVKVSNKAPSIKSGTYLLNQSYSNNDIISL
                     LVSGKIYQDGIKVTIPEGATSKEIIAMLVSKNLGDKATFENLIKKPQEFYDKFPYLKE
                     DGITSLEGFLYPETYYFNSKKQSEEDILSEMLKVFDSKYTDKFKKKQKELNMTLQEVM
                     EMASIIEKEAVLDKDRPIIASVFYNRLKVGMPLQSDATIQYIFEERKKIVTYDDLKID
                     SPYNSYKNKGLPPTPISNPGIKSIEAALYPEKTDYLYFVAKIDGGNNYSTNYQDHLKY
                     VKEYKEARDKQSKDTKATNKENTKK"
     gene            50292..50966
                     /locus_tag="PC466_000845"
     CDS             50292..50966
                     /locus_tag="PC466_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HDF2768267.1"
                     /translation="MSNIVNDLVEDYIRVTLKEKEGFLKDLEIYAEENSVPIIHKEVS
                     DLLKVLLKVQKPKRILEVGCAIGYSSIFFASIIGKDADIITVERNEKMIEKAKENIKL
                     AGFDNNITILEGDAEEKLSQVQGEFDLIFIDAAKGQYKLFFDLVIDKLKDGGLLVSDN
                     ILYKGMVAHDDFVVRRKKTIVKRMRNYLDYICNCDYLSTSLVPIGDGVALSYKESKRG
                     DVDGIK"
     gene            50953..52200
                     /locus_tag="PC466_000846"
     CDS             50953..52200
                     /locus_tag="PC466_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HDF2768268.1"
                     /translation="MELNKVELLAPAGDLERLKIAITYGADAVYIGGEIFGMRSAAKN
                     FSKEDMAEGVAFAHERGKKVFVTVNIIPHNEDFLQLEDYLLELEEIGIDAVIIADPGV
                     LSVIKKVIPNMEIHLSTQANTTNYLSANFWYEHGIKRVVVARELSFDEISEIRAKTPL
                     DMDIEAFMHGAMCISYSGRCLISNYMTGRDANKGSCAQSCRWQYHLVEEKRPGEYFPI
                     YEDERGTFFFNSKDLCMIEYIPELIKSGITSLKIEGRMKTAYYVATVVRAYRMAIDEF
                     YRAPENWKFNPMWMEELKKGSHRHFTSGFYLNKPTTEDQNYQSASYVRNYDFIGIVRE
                     TEDEDGLIVVEQRNKMCVGDEIEVMGPYKETMFTKIEEMYNEEGEAIESAPHPRQIVK
                     LKLSVKVGKDYMLRKVIEEKVEE"
     gene            52272..53936
                     /locus_tag="PC466_000847"
     CDS             52272..53936
                     /locus_tag="PC466_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HDF2768269.1"
                     /translation="MSKKKTPFLKKVGKRSWCIFTIILIIYSVLIYRLVDIQVLKGDK
                     YKQSVESQSVEKVELNSGRGIIYDRNNKKLTDTSKSQVLIVEKEKLNNNYKILELIKK
                     ATKMNDLDIYKAVQEQLTRPIIQIQTKNIDKSMKKELEKNGIMVEEKTMRYAKDGLLS
                     HTIGYIKEDDKSGQSGIEKSMDSVLRNSNEKYISAFKAGDAGNEKSLNILKGSVKTVD
                     NKDKDRHLKTTIDYNIQKKLEQILNKEENPTAAIISEASTGEILAMCSRPNFDQNDIS
                     KSLKGKNGEFENRVIKATYPPGSVFKMVVLFSALENGVIDENYTYNCTGKTKVGNTNE
                     ILRCNKRDGHGFQNLRQAFSNSCNPAFLDIAMKLGKEKILKSAEKLHLFEKVDIGLDE
                     EKIREAPKNISIRNLAIGQENIEFTPLQINQMTQIIANNGTFKPLYLYKSLVDNNMNT
                     IKTYKSSKKEELISPYVCTQVKEYMKSVSRIGTAKDLKDIEGGCGVKTGTAQSSLNKK
                     AIDHGWITGFYPEERPKYVITVLVEGTQKGNKSATPIFKEICESIK"
     gene            complement(54033..54317)
                     /locus_tag="PC466_000848"
     CDS             complement(54033..54317)
                     /locus_tag="PC466_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012063608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDF2768270.1"
                     /translation="MCNEISLLDILGTEANYVLDEVELKVQVGKLYEQLNKILTPRER
                     EIVQLRYGLTPYGYKTQREIAQKLDISRSYVSRIEKKALKKLEKELVQES"
     gene            complement(54340..55857)
                     /locus_tag="PC466_000849"
     CDS             complement(54340..55857)
                     /locus_tag="PC466_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDF2768271.1"
                     /translation="MSVAIYLRKSRADEEAEKQGEFETLSRHKSTLLKLAKEQNLDVI
                     EIKEELVSGESIIHRPKMLELLKEVEENKYDAVLVMDLDRLGRGDMKDQGIILETFKE
                     SKTKIITPRKTYDLTDEFDEEYSEFEAFMARKELKLISRRMQRGRIKSVEEGNFIGTS
                     APFGYDAVTTGRKERILVPNKDADVVRTIFDLYINEDMGCSKISKYLNNLGIKTATGA
                     NWYNSAITNIIKNKVYCGYIQWQKKDYKKSKNPNKIKTVKLRPKDEWIEAKGKHEPLI
                     SEITWKKAQNILKKNGHVSYGNQIKNPLAGIVICKNCGRPLVYRPYADHDYIICYHPG
                     CNKSSRFEFIEAAILKSLEDTVKKYQLKACDLDLDKNNKDSNIEFQKRVLKGLETELK
                     ELGKQKNKLYDLLERGIYDEDTFIERSNNISSRTEEIKDSIKTVKNRLSTVKKDNSKI
                     IEDIKTVLSLYHDSDSLGKNKLLKSVIDKAIYYKSKEQKLDSFELMVHLKLHEDQ"
     gene            complement(55982..56803)
                     /locus_tag="PC466_000850"
     CDS             complement(55982..56803)
                     /locus_tag="PC466_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HDF2768272.1"
                     /translation="MIISKKITAILVSFLIMISMVGCAPKESATEVAKKYLDSIEIKD
                     YEVAYNLLSKDSKESVSLEKFEEYQDTLFKLQTLKDYKLGEENKVEKYKYSNKEYTNL
                     VKIKETDTIKYITENKEDTANFDRYFIIEDNEYKLLWHKDFKRALSSNYVKIARSETK
                     KDEDKDYNKAAIDIKKAIEIDDKNPLAYYTQSYIYIELQRYDEALKSIDKSLEYLDKN
                     NEAYKIDASDAYNLRGVIFMSKSEFNKARESYNKALELNPDNEYAKTNLNDIKGL"
     gene            56994..58421
                     /locus_tag="PC466_000851"
     CDS             56994..58421
                     /locus_tag="PC466_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp26"
                     /protein_id="HDF2768273.1"
                     /translation="MKIKKLLTIGLSLSIFIASCPISANALDKIESIKGADKYETAGI
                     IADKQNYTTAILINADSTMADGLSASGLAGAINAPILLTKKNNIPNATLKRLEKAKKV
                     YIIGGENSINKYTETVLKGKGIEIKRLQGSDRIKTSYNVAKEINSINKVNKVILTNAF
                     KGEPDAMSAAPVAVRDKAAIVLTDGKSVPFNTTGVESYVIGGTSSMNDKLVKDTNSTR
                     LGGTDRYDTNKKIINKFYSGVKEFYIASGTDLVYALVGSTIAKNNAIVLVGNDSNKSV
                     LKSTIKLTAIGNLSDSILQQCLNVTKNIGDSNTGREYTVEDAANAVKKLLGVKKFYYE
                     PNYSEDEDLIFLLDKNFDFSGKEYYVFAYIKQGAEGDVRYCVAKNDMSKVYTYDVNGN
                     MKVCNPDDYKNKGSITEEQAKQIALKECAKRHKVSINNLVVDMIDFRDDIYSGNVYAV
                     KINSKNSNGTFGWFFIDIETGKIYN"
BASE COUNT        23506 a         6104 c        10736 g        18364 t
ORIGIN      
        1 aaaagataga gttttattta gacatttatt acaaatcaaa atttattaca tattatttat
       61 aaaaaaatct aaggaggaaa taataatgaa aatattagta ttaaactgtg ggagttcttc
      121 attaaaatat caattaatag atatgaataa tgaagaagtt ttatgtatag gattggttga
      181 aagaatagga atagaaggtt ctatattaaa acatgaaaaa gcaggtagag atgataaata
      241 cgttgttgaa caaccaatga aggaccacaa agatgcaata gcattagttt tagaagctgt
      301 tgctcatcca gaatttggtg cagttaaaga aatgaaagaa atagatgcag taggacatag
      361 agttgtacat gctggagaaa aatttgcaac ttcagtagta ataactccag aagtagaaga
      421 agctttaaaa gaatgtatag atttagctcc acttcataat ccagcaaaca taatgggaat
      481 agatgcttgt aaagctatac ttccagatgt accaatggta ggtgtatttg atactgcttt
      541 ccatcaaaca atgcctaaat cttcatactt atatggttta cctcatgagc tatatactaa
      601 atatggggta agaagatatg gattccacgg aacttctcat aattatgtat ctcagagagc
      661 agcagagata ttaggaaaag atataaaaga tttaaaaata gtaacttgtc acttaggaaa
      721 tggtgcttct atagctgctg ttgatggtgg aaaatgtgta gatacatcta tgggattcac
      781 tccattagaa ggattaataa tgggaactag atgtggagat atagacccag ctatattacc
      841 attcttaatg agaaaagaag gtttagatgc tgatggattg gataaattaa tgaataaaga
      901 atctggagta tatggaatga ctggaatttc tagtgacttc agagatatag aagatgcagc
      961 taaaaatgga gacgaaagag ctcaggctac attagaagcg tatgttaaaa aagtacaaaa
     1021 atatataggc gcttatgctg ctgaaatgaa tggattggat gttgtagtat ttactgcagg
     1081 cgttggtgaa aatggaaagg ctataagagc agatattgct tctaacatgg agtttttagg
     1141 aatgaaatta gataaagaag ctaatgatgt tagaggaaaa gaaacagtaa tatctactgc
     1201 tgattctaaa gtaaaaatgc ttttaatacc aactaatgaa gaattaatga tagctagaga
     1261 tacattaaga ttggtaaaat aattaaatta aacctatgcc tatcaagtaa aaatacttga
     1321 caaacaaatg ctagatttgt ataataaatt tggtgatatg ttgaggtgaa cttaatgaaa
     1381 gttagcatag aaaaaataaa tagaaaagaa actgacaaaa tagacttgaa tttttgtgaa
     1441 aaaattgata ctattagtta ttgtgatgag atttacaaat tagtatcacc tgtaaattta
     1501 aaagggaaag tgtcaaagac taataaaggt ttgtatctag atatagatgt caattttaca
     1561 attgttgaca cttgttcaag atgtcttaaa gaagtagaaa taccactaga gtattctata
     1621 caaggttttt tagtaaaaga agaagattat gatgaagatg agtttgagga atttgatcct
     1681 tttatattcg atggtgaaga aatcgacctt attgatataa tagaacagac attagatttt
     1741 aatgtacctc ataaagttct ttgtagtgaa aactgtaaag gtctttgtca agtatgcggg
     1801 gcaaacttaa atgaagaaga gtgttcttgc agtgaaatta caaacgatga ggaatacata
     1861 gatcctcgtt ttgctaaatt aaaagattta tttaattaaa ttttgactaa ggaggtggcg
     1921 taaatggcag taccaaagcg taaaacgtct aaatcaaaca caaaaatgag aagagcagct
     1981 aactcaaaga tggaagcaac aggatttgta agttgcccac aatgtcatga gccaaaatta
     2041 ccacatagag tgtgtccaga ctgtggatat tataaaggta aagaagttgt gtctaagtaa
     2101 tagcttctaa aaagcatgta gagtatactc tacatgtttt ttttgtacat ataaaaaaat
     2161 aagatgattt actagagaaa ataagtggat tttatgcata ttaaaaaata gaaaaataat
     2221 aatataagta ttgaaaattt ttgtgtgtta ctatatacta ctattagtag ctggtactaa
     2281 ttacagctat aaaatttgga gggaacatga aaaagaaaag taaagcccaa agacaaaaag
     2341 agcttataga tatgctaaag acagatcctt tttatactga tgaagaatta tcaagtctgt
     2401 ttgatgtaag tatacagacc ataagattag atagaatgag tctaaacata ccagagctaa
     2461 gagaaagagt caaatcaata gcagaaactc agagttcaaa agtaaagact ttaggagtaa
     2521 aggaaattac aggagaaatc attgatttat ctgtagggcg attaggtata tctatgttag
     2581 aagttacaca ggacatgatt tactctaaga ctaatacttt aaaagatacg tatatttttt
     2641 ctctagcaga ttcattggca atggctataa tagatgcacc taaggttatt atgagagttg
     2701 caaatgtaaa aagttttaag ttgatagaac aacaagatag acttatagca aaagcagaag
     2761 tgtatagaaa tatagataaa aagcattatg taaaagttgt tatcaacaat aaagcccaag
     2821 agcaaatatt tagaggaaag tttatctttg aagaattaga ttaggaggga aattatgaaa
     2881 atagtaattg atggaatggg tggagataat gcacctaaat ctaatgtaga aggcgcagta
     2941 aatgctataa aagaatatca ggttgattta ataatcacag gagataaaga tttacttgaa
     3001 aaggaatttt caaattatga atttgataga aataaattag agatagttca tactactgag
     3061 attatagaaa acgaagataa accagtaaag gctataagaa gtaaaaaaga ttcatctatg
     3121 gtagtagcat taaatcttgt aaaagaagga aaggcagatg ctataatatc agctggaaat
     3181 acaggagcct tacttgctgg tggattattt gttgttggta gaataaaagg aatcgataga
     3241 ccttgcttat gttcagcaat accaaatgta aagcgaggaa tgacacttat agcagactgt
     3301 ggcgcaaatg cagattgtaa acctaagaat ctagttgaat ttgcagctat gagtaatatt
     3361 tattcaagaa aagttttagg tcttgaaaat cctaaggtag cattagcaaa tgttggacta
     3421 gaagaaggca aaggcaatga tttagtcaaa aggtcatatg aagaaattaa aaaattagat
     3481 ttaaatttta tagggaatgt agaagctaga gaagttataa atgcatacac agatataatc
     3541 atatgtgatg gatttacagg taatatatta cttaaatctg ctgaaggtgt agcactttca
     3601 gttatgagtc ttataaagga aacttttatg gccagtacaa aaagtaaaat aggagcatta
     3661 cttataaagg atgatttaag aaaattaaaa agttttatag attattctga gtatggggga
     3721 gctccacttt taggtctaaa tggaggagtt ataaaagctc atggtagttc tgatgctaaa
     3781 gctataaaaa atgctataaa tcaaggaata aaattttcaa agggaaaagt cgttgaagat
     3841 attaaccaat ttataagcaa atacaatgaa gaaaataaaa ataacgaaga tgaataaact
     3901 cgttttggag gtttaatata taatgaatac aaaggctgga atattaggag taggaagtta
     3961 tctacctgag caatcatatg ataattttca cttcgaaaaa ataatggata catcagatga
     4021 gtggataagt actagaactg gtattaagga aagaagattt gccaaagagt ctgaagcaac
     4081 ttctgactta gcatctaaag ctgccttaaa agctatagaa tgtgcaaagt taaacgtaga
     4141 ggatatagag ctgattatat tagctacaat tactcctgat atgtctttgc cttcaactgc
     4201 atgtatagta caagatgcaa taggagcagt gaatgctact gcatttgata tatcagcagc
     4261 ttgttctgga tttgtatatg gagtaactat tgcaaagcaa tttgtggaaa caggttgcta
     4321 taaaaatgtg cttgtaatag gagcagaaac ttgttctaag tttttaaatt atgatgatag
     4381 aacaacagca gtattgtttg gagatggagc tggagcagct gttattggtc ctgtaaatga
     4441 gggtggaata ctgtctacac atatgggctc tgatggtaaa ggaaaagatt gtttaaaagt
     4501 acctgctgga ggttcaagac ttaaggcaag taaagagact gtagaagcta atctacatac
     4561 aatagaaatg gcaggtagtg atgtgtttaa atttgcagtt agaaagatgg cagaaacttc
     4621 tttaagagct cttgaaaaag caaacctaaa tacaactgat atagactact tagtgccaca
     4681 tcaagctaat ataagaatca tacaagcttc ttctaagaga ttagagcttg atatgaaaaa
     4741 agtttatgta aatatagaca aatatggaaa tatgtctgct gcatctatac cagtagcatt
     4801 agatgaagct tatagagaag gtaaaattaa aaagggtgat aatgtagttt tagttggctt
     4861 tggtggaggt ctaacttggg gggcttcagt tgtcaagtgg actttatagt ataaaatatc
     4921 taaaatgatt taattaacaa aattaaactt atacacaaaa taaagttgat taataataaa
     4981 aagtttactt ttatgatttc aagtgaagga gaattgtatg aataaaattt gcaaaatatt
     5041 aaatataaaa tacccagtta tccaaggggg aatggcatgg gtagctactg catcattagc
     5101 aagtgctgta tctaatgcag gaggacttgg cataatagca gcaggaaacg caccaaaaga
     5161 agctataaag aaagaaattg ttgagtgtaa aaaattaaca gataaacctt ttggagtaaa
     5221 tgtaatgctt atgtcgccat ttgttgatga tataattgat ttgattatag aagaaaaagt
     5281 tcaagttatt actactggtg ctggaaatcc tgcaaaatat atggatagat taaaggaagc
     5341 tggaacaaag gttattcctg tagtacctac aatagctttg gcacaaagaa tggaaaagtt
     5401 aggagctaca gcagtaatag cagaaggtac tgaaggtgga ggacatatag gagaacttac
     5461 tactatggtc ttagttccac aagttgctga tgctgtaaac atacctgtaa tagctgctgg
     5521 aggaattgta gatggtagag gaattgcagc atcatttgca ttaggtgcca gtgcagttca
     5581 agtaggaact agatttattt gcagtgaaga gtgttctgtg cattcaaact ataaaaactt
     5641 agtactaaaa gcaaaagata gagatgcaat tgtaacagga agaagtactg gtcatccagt
     5701 aagaacatta aaaaataaac tatcaaaaga atttttaaag atggaacaaa atggagctac
     5761 tcctgaagaa ttggataaaa aaggtacagg agctttaaga tttgcaacag tagatggaga
     5821 catagaaaaa ggttcattta tggcaggtca aagtgctgct atggtaaaag aaataacacc
     5881 ttgtaaggaa attatagagg ctatggtaaa tcaagcaaga gagattatgc cagcaataga
     5941 actgtaaatc aggaggagca agatgggaaa agttgcacta gtattccctg gtcaaggagc
     6001 tcaatatgta ggtatggcca aggatttata tgaaaataat gctgttgcta aaagtgtaat
     6061 agatgaggct agtgatgcct taaatatgga tttaaaaaac cttatgttta atggaaatga
     6121 agaagaactt tctaaaactg aaaacactca acctgctatg gttacacata gtgtagcagt
     6181 attaaaagcg gtacaagctc aaatagattt aaaatataat gcatgcttag gattatcctt
     6241 aggagagtat agtgcgttgg ttgcagcaga tgcaattgac tttaaagatg ctgtatgttt
     6301 agttaaaaaa agaggtaagt ttatgcagga aacagttcca gcaggtgttg gagctatggc
     6361 agcaatttta ggtttagata gaaatgtact tgaaaatgtg gttaaagata tacaaggagg
     6421 tattgtagaa gtagcaaatt acaattctcc tggacaaata gttatatctg gtgaaaatga
     6481 aaagatagaa gaagcaatgg taaaatgcaa agaagcagga gcaaaaaggg cagttaaatt
     6541 aaatgtaagt ggaccttttc actcatcaat gttaaaagaa gctggtgtaa aattggccag
     6601 tgaattagaa aaagttaaca taactaaacc taaagttgat gtggtggcaa atgtaaatgc
     6661 agattactat aaaaacgaag gtaaagacct gcttataaaa caagtaagtt catctgttct
     6721 ttgggaagat tctatagaaa tacttttaaa tgatggatat gatactttta tagaaatggg
     6781 acctggaaaa actttaaaag catttattaa gaagatagct tccaataaaa aagcaaatgt
     6841 caatatttat aatatagatg gtatagattc tcttaatgaa tttgtacaaa attatagaaa
     6901 tggagagata taatgataaa tcttacagga caagtagcag ttgttactgg tggctctagg
     6961 ggtataggaa aagaaatagc aaaaaaacta gcatcttttg gagctgatgt agtaatcaat
     7021 tatacttcta aagaagatga agcactaaaa actaaaaatg aaatagaaag tatgggggta
     7081 aagtgtacct ctataaaatg tgatgtgtct aaatttgatg aagtgaatca aatgatagat
     7141 tctgttgtaa gcgaatttgg aaaaattgat atattggtta ataatgcagg cataactaaa
     7201 gatggtctgc ttatgagaat gaaagaagaa gattttgata gagttataga tataaactta
     7261 aaaggtgtct ttaattgtac aaaagcagtt actaaaccta tgatgaaaaa gaagtatgga
     7321 agaataataa atatgacttc agtagttgga attatgggta atgcagggca aactaattat
     7381 tgtgcatcaa aagcaggtgt aattggattt acaaaagctt ctgcaagaga gttagcatca
     7441 agaaacataa atataaatgc agtagcacct ggatttatag aaacagatat gactagagta
     7501 ctaagtgatg atgtaaaaga atcaacacta gcaaacatac caaagaaatc ttatggtaaa
     7561 ccagaagatg tagccaatgc cgtagcattt ttagttagtg acatgtcaag ttatataaca
     7621 ggacaagtaa taaatgtaga tggtggaatg gtaatgcaat aataatttaa aaagtagaga
     7681 aatctattaa aataaaaaat tttaggaggt acacaatgtt taataaagtt gtagaaataa
     7741 taatagagca attaggagta gaagataaag aaataactat ggagacatca ttaatgaagg
     7801 atttagaagc agattcatta gatgcagtag aaataataat ggcacttgaa gatgaatttg
     7861 gtatagaaat accagataca gaagcagaaa acttcaaatc tataggagat atagttaagt
     7921 atatagaagc taataaatag tcgagcttta aaaaagtgga ggtatccgat gaataaaaga
     7981 gtagtaataa caggacttgg atgtgttacg ccgttgggaa cgggaaaaga agagttctgg
     8041 agtaatataa aatctggagt atctggtata gataaaataa ctaattttga tgctagcaca
     8101 tatcaaactc agatagcagg agaagttaag aattttcatc cagaagaata tataagtaaa
     8161 aaagaattga agagattaga taaatttgct caatttgcaa tagtatctgc taaattagca
     8221 gttgaagatg caaatcttga tttagataaa gttgatagag aacgttttgg tgttataata
     8281 ggttctggaa taggtggagt tgaagctata gaaactcaac ataaaattct tttggaaaaa
     8341 ggaaataaaa gagtaagttc actttttgta cctatgatga taggaaatat ggcagctggt
     8401 caagtttcaa tatttttagg agcaaaaggg cctaacacta atgtatgtac agcttgtgca
     8461 tcaggaactc attcaatagg tgatgctttt aaggtaattc aaagaggtga tgcagacatc
     8521 atggtagcag ggggctctga agctgctgta acaggtcttg cttttgctgg attctgtaac
     8581 atgaaggcta tgtcaactag aaatgatgac cctaaaactg catcaagacc gtttgataaa
     8641 gacagagatg gttttgtaat gggagaagga gcaggtattg ttatcttaga agacttagaa
     8701 catgctttag caagaggggc taaaatatat gcagaagtag ttggatatgg tttaactgct
     8761 gatgcatacc atatgacaac tccagctgaa aatggagagg gagcagctag gtctatgaat
     8821 atggctttga aagatggaaa tgttccatta gaagaagtag attatataaa tgctcatgga
     8881 acttcaactt attacaatga tttatatgaa actatggcta taaaaactgt atttggagaa
     8941 aaggcatatg acttatgtgt gtcatcaaca aaatctatga ctggtcactt attaggagca
     9001 tcaggtgcta tagaggctgt tgtttgtgct atgagtatag aagatagttt tgtgcctcca
     9061 actataaaca tacaagaagt tggtgaagat ttggatttag attatgttcc aaatcaaggt
     9121 aaagaaaaaa atattagata tgcactatca aattctttag gatttggtgg gcataatgct
     9181 acaatagtac taaaaaaata tgtataaata aatattaaat ataaaactaa aaaacaagca
     9241 cttgttttaa ctgtataaat ttatattagc ttaaatttaa agtctcctaa attattttag
     9301 gagacttttt tattaagatt taagtctagc atatgttgta aatcattttg atatattgta
     9361 ttattaatta ttaagaggtt atttatatat gcaagttttc attctacaat atacaaaagg
     9421 aggactaaaa ttttgaattt tagactacca aagaaaaggt tacccaaaaa gataattttt
     9481 atatgtataa tacttattag tattattttg tttataaagt atgaccaaaa tggattgaaa
     9541 gaaagagaaa ttataaataa gggaaaatat atgtctgaaa gccttgtggc agataaggag
     9601 tatgatgaag caaaaaaagt ggttaagact tctttcgaat ctattccaga aaaaaaatac
     9661 aataaagtat ataatgaagt ttgggatatg ttaaagacta tttcatatgt tccagatgga
     9721 acgaagatag tcattgattc tttagaaaag atgagagaat cagatgtgaa attatctgat
     9781 gaatgtagat ttaatataga aaaaagatta gcatcagtgt atataatgga taataattat
     9841 tctaaggcag tagatttaac tgtaaagtct ataaaattgg ctgagaaatt ggggaataat
     9901 tatgaaaaag caagactaga tgttgatttg gcgagcatat ttttaaatat aggtagctat
     9961 gaaacaggag agaaattaat aaaggattct tttaaaatag atattgatga aggtgaaaaa
    10021 aatggaatgg ttagattata tgctattata aatctagcag aaatatatgt agaagaggga
    10081 gaatatgata aagctattga aataagtagc aggataaaag attataaaaa gtttgtaaat
    10141 acggataatt acaatgattt tgatataatg gcctctataa tgaagtcaaa tgcgtatgtg
    10201 ggcaaaaata atatacaaaa ggcaaagact tttttagaaa aagctgatta tcttataaaa
    10261 tcagatagaa cagtttatat attagataaa gatatgtact attatatggc aatgggaaac
    10321 ttagaatata aaagcgaaaa ttataattct gcaatagata attataaaaa aagtttagag
    10381 atatctacca aaagaaagtt aactcaggag aaaataaaaa atttaaataa gatattaaat
    10441 atatatgaaa aacaaggaaa tatagaatct ttaaatgagt atcaaaagat gttaataaat
    10501 gaatataaag agaacaaaag tataagagat tcagagacta gtttctatat aattgataaa
    10561 gtatcaaacg aaagtaagct atttgaaaaa actaaaaaag aaataaaata ttataaaata
    10621 ttatttacag taattttaat tgctatatta gggtctactt ttttatacaa ccgattgaag
    10681 tattttaaag cacaaaattt acatgatggt cttacaaatg tttataatag aaaaagtttt
    10741 gatattatgt atgaaaagta cagagagaaa gatgataatt ttgcacttgt gatgatagat
    10801 attgataatt tcaagctcat aaatgataat tatggacata aatttggtga cactgttata
    10861 aagggaataa caaataccat ttgtgttatg ttagaacaag atgataaagt ctttaggtac
    10921 ggaggagaag aattttctgt attaataaga aataaatctg gtgaggaagt agcagatata
    10981 attgacaata taagggttgc aattgcaaat aaaaagtgga atgatgatgt gactgtgact
    11041 ataagtgcag gtgtagctca tatttcagat agcaaagatg tactagaaga agctgataaa
    11101 aatttatata aagcaaaaca acttggtaga aataaagtag tatataagta attatatact
    11161 atataaataa gaggtataaa tatgaaacaa tcaatagcta tagtaactga taaaataact
    11221 aaactatcat ctttcttaga agaaaatata cgtttggttt taggtaatta tattgatata
    11281 aaccactatt atctggaagt tttaaaagag aatgataaaa tacaaggtga ttttgtacta
    11341 gtaatgaatg atgatagatt aaacagtatg agaaagcatt tagtacaaga tagtaagatt
    11401 atagtgataa ggagaacact taaagaaaat gaaatatatg gattattttc aataccaaat
    11461 ggaactgaag tattggttgt aaatgataca aaagaaacta ccttagaaac gataagctta
    11521 ttttacaaaa taggagtaaa aaatttaaag tttactccat atattgaagg aaaaatttat
    11581 aaaaatatag acatagctat aacgcctgga gtaaaggaaa aagtaccaag ttatataaat
    11641 aaagtaatcg accttggtaa tagatatatt gatatatcta cttttataga aataataaat
    11701 ggtcttagaa ttgatgttaa agaaatacgt aaaaatttaa tggcatattc tgagagttta
    11761 ataagtttag ataatggagt taaagataat tataggcaac tgtttttaaa aatagaagaa
    11821 caagatgtta tattgaatct atcaaaagat ggaataatat ttacttcagc agatggtata
    11881 ataaacacat ttaataaaga agctttaaaa attttaggta taaatgaaaa tccacaaggc
    11941 aaaaacatag aagatatcat ttctgaagat ttaaatattt tacttgaaga caaagaaata
    12001 attgatgaag tggtatttac aaataaaaaa tatataaatg taaataaaaa aagtattttt
    12061 tctatgggga ataaagctgg gatatattat aacttacaag aaataacgta tataaaaaaa
    12121 ttagaacaaa atcttactaa taaattaaga gaacaaggtc agatagcaag atatacattt
    12181 aaagatataa aaactaaaaa taaaaatatg gtaaagtgtg tagaattggc taaaaaaata
    12241 tctaaatcag acctttctgt attaataata ggagaaagtg gtactggtaa agaattatta
    12301 tcacaatcaa ttcataatgc ttccaataga agtaatcaac catttatagc ggttaattgt
    12361 gcagcagttc cagatagtct attagaaagt caactgtttg gatatgaaaa aggctctttt
    12421 acaggagctt taagagaagg aaaaaagggt ctatttgaac ttgctaataa tggaactata
    12481 tttctggatg aaattggaga tatgcctcca ttgctacaga caaagttact aagggtatta
    12541 caagaaaagc aggttatgcc tataggttcc cataatgtta taaacataga tgttagggtc
    12601 atagcagcaa caaacaaaaa cttactaaag atgattagag aaggaaaatt tagagaggac
    12661 ctgtattata gactaaatgt attgccaata gatgtaccat cattgaggaa tagaaaagaa
    12721 gatataataa cacttatgaa tttctttttg aaaaacaatg taagactttc gccagaagtt
    12781 ataactattt tagaaaaata taattggcca ggaaatataa gagagttaca aaatgttgct
    12841 tcttatgtaa gtctaatgtg tgatagtatg gtttttagag atgacttacc accatatata
    12901 agggtagaat gtgctaacaa ttatgaagat ggatttggtt atacaaaaaa agaatttgag
    12961 gaaatactga ggattctata tgaaagaaga gagtcatcct ctggagttgg aagagggttt
    13021 ataatcgaaa agcttataca ggaagggatt gagatttctg aaagcaaagt tagaaaggtg
    13081 ctatcttatt taagtgaatg tggatatata tcatctaaat ctggtagagg aggaagtcaa
    13141 ataacctcag aggggataaa actttataat aatataaatt aagctaagta tttgatattg
    13201 aaatcacata ttttgaattt agatatttaa ataataaact tttatattta tagagattaa
    13261 tttatactat gtcagaaaga atattgtaat ttataattaa atattaatag gtttttaaaa
    13321 taggattaga taggtaatag gttaagttag aataacccat tacctatttt tatttgtaag
    13381 aaaagtgtac atagagttaa aagtaaaaaa tacaactaat aaaactattg aaaacactag
    13441 ataaataata aataaaaata attataaatt ttggcatata tattgctaat catagagata
    13501 agacgacaaa ataattggga ggtttaatga tgaaatacaa aacaacaggg acttgtgcta
    13561 cagaaattga atttgaagta aaagaaaata aagttacaaa tgtaaacttt ataggtggat
    13621 gtgatggaaa tttaaaaggg ctaaaagtat tagttgaagg catgaatata gaagatgtaa
    13681 tacaaaagtt aaaaggaata gagtgtaaaa caaagccaac atcttgccca gaccaactgt
    13741 ctctagcatt ggaaaattat atgaatataa agtaatacat aaaacaatcg attagttagg
    13801 agtttaatta tgaaaccaat aatagggatt ttaggaaatt taataataat ggaaaatggt
    13861 atgtttccag gtcttgaaag gtcatatgta aataatgatt atataaatgc agtgctaaaa
    13921 ggtggcggta gtccagtaat aattcctgta aatacagata aagaagttat aaaaaaacag
    13981 attgaaatgg ttgatggagt cttaatatct gggggatggg atatcaatcc tcaactgtat
    14041 ggagaagaaa caagagaaga aacgacattt atatatccag aagtggatga atttgattta
    14101 attgcaataa gtatagcatt agaacttaaa aagcctatat taggtgtatg taggggacta
    14161 caaattttaa atgtaagttt aggaggaact ttatatcaag ataataatct tatagaagga
    14221 agttatataa aacatacaca atcttctaaa agacatgtag ctactcataa agtcgatgtt
    14281 aaagaaggaa gtattttaga gggaatttta ggaaaacaat tacttacaaa tagttatcat
    14341 catcaaagtg tcaatcagct tggaaaagga ttaaaagcca tagcatactc aaaagatggt
    14401 ataatagaag ctattgagaa agaggaggaa aattttgtag taggagtaca gtggcatcca
    14461 gaaatgatgg tagattactg tgataaaatg gaaaaactat ttaaatattt tataaatatt
    14521 tgttcaaatt tataatatac cttgggggga ttgaacatga acgaaaagaa caaaatggga
    14581 ttaataagta ttatactttt aggtattaat gcagtagtag gagctggagt ttttctatta
    14641 ccaggagatg caatgaaatc atttggtgta gcaagtatat ttgtatatat atttgatatg
    14701 ttgttagttt tatctatggc attctgtttt gctgaggttg caggtaaatt caataaaaat
    14761 ggcgctgcct atgtatatac caaagaagct tttggagatt tttgtggttt tgaagtaggt
    14821 cttatgaaat gggtaatagg atgtatttct tggggagctt taatagtagg ttttcctaca
    14881 tcattatcag cagtatgggc tccagcaggt gaaccacata tacaaaaaat tataattgta
    14941 gccatgatag ttgggcttac aattataaac ttattaggtg tatctctatc aaaaattgta
    15001 caaaatgtta taactgtagg taaactaatt ccattaatac tatttatagg aataggtata
    15061 ttttttataa aaggagttaa ttttacttct tcaacaatgg tacctccagg agctggagca
    15121 acagagtttg gagcagcagc acttttaatg ttttattcat ttacaggatt tgaatctata
    15181 gcagttgcag cagaagatat ggaaaatcca caaaaaaata taccaatagc aattataagt
    15241 gtaatagtaa ttgcatcaat aatatatata ttaaatcaag ttgtatgtgt tggtatacta
    15301 ggagattcgt tatctagtac atctacacca gtggcagatg ctgcaagaat atgctttgga
    15361 aatatgggag ctggattggt tacctttgga acattggttt ctgttggtgg aatttgtatg
    15421 tgtggtgctt ttgtaaatcc aagaagttgt gtagctttag ctgatgataa aatgttacca
    15481 agaatatttg caagaaaaga taaaaaaggt acaccatatg tagcgataat agctactatg
    15541 ttaatcacta taccaatagc tctatctgga agttttgctg aattagcagc aataagtgca
    15601 gttgctagat tcatacaata cataccaaca tctttatccg tattagtgtt tagaaagaaa
    15661 agaccagaat tagtaggtac ttttaaaact ccttttggag cagtgattcc tctaattgct
    15721 gtatgtgttg gaacatggtt gttattccaa gcatctatgc atcaattaat tatgggatta
    15781 ggagctttgg caattggagt accattatac tttataatga agtcttataa tagaaaagtc
    15841 tgtggtgaaa atttaaagaa aatagtttaa ttatgttata agaatttatt gagttaaaat
    15901 tagacattgg cagaaaatta aatacaaata agtatctata aggctatatt aaaatattat
    15961 taatttttta ttttaatata gccttatatt gttatcaata aatgaaaaat attgtaacaa
    16021 cagaagaaca atagtattat gtttatagat aaaaaactta ttaggaggta aatttatgcc
    16081 aacaataaca ttaaaaaatg gtgtagacgt acttattaga gaaggtgtaa gagaagatgc
    16141 ttaaagcatt atagattttt ataatgaagt gggtggagaa actcattttc tgtcatttgg
    16201 aaaggatgaa tataaaatat ctttggagga acaagaaaat gctatagaat cagcaaaagc
    16261 atctgataat tctgttaaac tgattgcatt tatagatgat gaaatagttg ggattgcaac
    16321 gattgattct aatcaaaaag caaaaggaaa gcatgttgga gtattaggaa ttgttgtaaa
    16381 agaaaaatat tggggaattg gattgggtaa aaggcttatg ttagacctta tagaatggtg
    16441 taaatcaaat ggaataacca agaagataac tcttgtcact aatgaagaaa attataatgc
    16501 tataggatta tacaaaaaag ttggatttga agtagaaagc atactaaaaa aagaatgtta
    16561 ttataatggt gtttatactg atttaatagg aatgtcactt ttattgggaa tataattagt
    16621 gtacatttta tctcgaaaaa agtatattaa gtatggtata attaaaaaag aatataactt
    16681 aatataattt tggaggacga attatgaaaa atctgtgtaa aatatcagat gattatttaa
    16741 acagcaagct taagtattta aagttattat caaaacaata tccaagtata tcaaaagcaa
    16801 gtacagaaat aataaattta gaggctatat taaatcttcc aaagggaaca gagcatttta
    16861 taacagatgt acatggtgaa tatgaaccat ttgtacatgt attaaaaaat ggttctggtg
    16921 taataaagag aaaaatagaa gaattgtttt caaatacaat aagagacagc gaaaaaaaaa
    16981 tgttagcaac tcttgtatat tatcctgaac aaaagttaga cctaataatt aagcaagagg
    17041 aaaatataga tgatttttat agaataaata tttatagact tatagaactt tgtaaatatg
    17101 cttctagcaa atatactagg tctaaagtta gaaaactgtt accagaaaat tttaaataca
    17161 taatagaaga acttttgcat gagcatgtta aaagtgaaca taaagaagag tattataaaa
    17221 gtatagttga aacaatagtt gacataggaa tagctaagga gtttataatt gctatttcta
    17281 cagttataca aaaattggtt gtagatagac ttcatgtaat aggagatatt tatgatagag
    17341 gtccaagacc agatataatt gtcgataagc ttattgaaca tcattgtgtg gatattcaat
    17401 ggggaaatca tgatatattg tggatgggtg cagcctcagg tgaaaaaact tgtatagcaa
    17461 atgcactgag gatatcagct agatatgcga atttagacat tgtagaagac atatatggaa
    17521 taaatctgtt gcctttagcc acttttgcta tagaaatgta taaagatgac ccttgtaaag
    17581 aatttattcc aaaggttaat gaccaaagtg taacaacaac agaaaagtct ttaatggcaa
    17641 aaatgcacaa agcaataagt ataattcaat ttaagcttga aggtgaggtt ataagacgaa
    17701 gacctgaatt tgaaatggaa catagacttt tgcttaatat gataaactat gatgaaggta
    17761 cgattacttt aaaaggtaaa acatataaat taaaagatac ttatttacct acaatagaca
    17821 aaaaagaccc atataaatta actatggaag aaagaaatgt tattgataaa ttagtatctt
    17881 catttagagg tagtgaaaaa ttacaaaaac atgtttcatt tttgttttct aaaggaagta
    17941 tatatttaaa ggctaactca aatttactga ttcatggatg tgtaccatta aatgaagatg
    18001 gaagctttat gtctatgaat ataatgggaa aagagtataa aggtaaggct cttatggata
    18061 agatggagtc tctagcaaga gaaggatttt tctttaaaga taaggcagaa gaaaaactat
    18121 atggtatgga tattatgtgg tatttatgga ctgggaaatg ttcatcatta tttggtaaag
    18181 atgatatgac tacatttgaa agatacttta tagaagaaaa agagactcat aaagaaaata
    18241 agaatccata ttttaaactt agagaaaatg agatggcttg taaaagatta tttgaagaat
    18301 ttgatttaga gcttgatgaa tcccatataa taaatggtca tgttcctgtg gagagtaaaa
    18361 atggagagag cccaataaaa gctaatggta aaattctcgt tatagatggt ggtttttcta
    18421 gggcttacca aaaaactact ggtatagctg gatacacttt gatatacaat tctagaactt
    18481 tgcaattagt atcgcatgaa ccatttaatt ctgctgaaga agccattgca aatgaaagtg
    18541 atatcttatc gacaactgtt gtagtagagc ataaggcaaa gagaaaaatg gtgagagata
    18601 ctgatgaagg agtaaaaata caagaggaaa tagaagattt aaaactactt ttaatggctt
    18661 ataagaaagg gctaataaaa gaaatgtaga tattatagag gcacttcata attgaagtgt
    18721 cttcttgtta atacttatta aatatattat aaagattaat aatagtagtt tatattatac
    18781 ttactaagtg aatccaagat aaatgggttc acttttttta tttataaaca ttattaaaaa
    18841 aatatagatg ttttggttat attccttgtc ctttataaat agaattatat aaacaaagga
    18901 ggaggacaag agatgaataa actttctgat gaaataataa actctctttc tacaactata
    18961 agagaaaagg tagaaaaagt ctcaaacaat aatctgaaca tagaagaaat taggttacgc
    19021 tcacaaaaac cattgatact aaatgcaaac tctaaagatt atttttacaa tcaaaaaact
    19081 atgacacttg atttaaatca acaaaactca tatgtagtaa caagagaaga tgtagagcaa
    19141 acttttcaaa taatatgtaa atattcaata cattcattta tggatgacat aaaaaaagga
    19201 ttcataactt tgagaggagg tcatagagta gggttagttg gaaaagcaat agtagaagat
    19261 ggacaagtca aaaatataaa gcatatatca tctttaaata taagggtatc aagggaaatt
    19321 attggatgct cggataagat tttaagtcat attataaagg gaaaaaatca gattaataat
    19381 actttgataa tatcaccacc tcaatgtgga aaaacaactt taataagaga tatagtaaga
    19441 aatttaagta atggtaatga agattatgga tttaaaggtt taaaagtagc tttggtagat
    19501 gagcgtaatg agatagcagg agcttatcta ggtgttccac aaatggatgt gggaataaga
    19561 actgatataa tagaaacttg cccaaaagat ttgggtatta cgatgctttt aaggtctatg
    19621 tcaccaaatg ttattgtgac agatgaaatt gggagtgaaa aagaaataaa ggcattatac
    19681 acagcattaa atggaggtat aggattaata actactgtgc atggagattc aatagatgat
    19741 atacaaaata gaaaagaatt aaatagactt ctggataaag agttatttaa aaaggttata
    19801 attctttctg caaaaagagg agcaggaacg attgaaaaaa tttatgattt agaagaaaag
    19861 agatggtatt ttgcaaatta aaataattat tatagctctc ttggtaggaa gtagttattt
    19921 gataggtgaa caaatataca aaacttatac tcgtagacat aaacaattaa acgatttaat
    19981 aagagtttta gaaattttga ggatggattt atctttcgga ctttatacat tagaagaaat
    20041 ctttaatagg ataggtggaa ataaagagtt ttgtttttgg aaatttttct atcaaatatc
    20101 agaaggactt cacaatgaac aaagtaaaac tttggaaata ataatatcag aaaatattga
    20161 tgtcttaagt aaagaaactt atctaggcaa taaagaaatt gaggaactga aaaatctaat
    20221 acttacttta gggaaaagcg atatagagtc acaacaaaga atgatagatt tatctataga
    20281 aaatttgaaa aaacaaacct atgagacaaa ggaagatata aacaaaaaag gcgtattgta
    20341 taaaaaatta gtgacattca taggtatagg tatatgtatt atattgattt aatatgggga
    20401 ggtttattat ggaaatatca ttgatattaa aggttgcagg tgtcggtatt ctaatatcag
    20461 tattgaatat gatattggaa aaaacagata gaaaagattg ggcaggtctt actacattag
    20521 caggtgtaat aatcgtattg ggtatggtaa taacagaaat aagtgacttg tttaatactg
    20581 taagaacaat gtttcaactt tactaaaaag gagggagtaa tttggaaata atgcaattaa
    20641 taggaattgc aatcatttca actacactct gtttagtaat taaaaaagat agaccagaga
    20701 tagcaaattt catagcaata ataactggag taataatact attgtcagtt atgtttaagc
    20761 taaattttat agtagatagt atacaagatt tggctaacaa ggctaacata ccgactatgt
    20821 atatatcatt aataataaaa ttaattggga tagcatactt aatggaattt gcgatacaac
    20881 tttgtaaaga ttgtggggaa ggaaacattg cttcaaaact agaatttgga ggtaaaataa
    20941 tagttatgtc aatgtctttc cctatacttt tgtccattgt agaaatggtg gtgaatataa
    21001 ttccatagat gtgtatcttg gaatgaatat aagtatatta gagaactttc gttgtattga
    21061 ggtttataga gtgaagagag gcatggttgc ttatgaaaaa aagattttta ccaatgatta
    21121 taggtttttt atttactttc ttttttgtaa atatctttgc tattatgata tttgctaatg
    21181 aagtaccaag tagtgaagat aaagaatatg gtgaaacaaa aaatagcata gataaatata
    21241 tagatggtca attagacaag ctagatataa atgagattca agactatata aataaagaaa
    21301 tagttattaa tgatgttaat ttaaaatcat ttgtaaaaga tttaattagt ggagaaaaaa
    21361 atatcttaga tttattcaat aaagatggat tgaagatatt gatgtttgat gaatttaaag
    21421 caagtttaaa ggtagtagca gtaattttgg tactggctct gttatcatct attttaaaga
    21481 gtctggaaaa ctctttttca tcaggtgcag taagtcaaat agcaacatat ataatattta
    21541 tcacaatggt atcacttaca cttattggtt ttaaagatgt attacagatt tgttatgatg
    21601 caatagacca tactgtaggt cttatgcaag ttataatgcc aatattaata acatttttac
    21661 ttttaattgg gttcccaata acgtcgacta ctttgaatcc tatcttcata ggaggagtaa
    21721 catttataaa tgtatttttt aaaaattttc tatttgtatc tattactgtt gcatttggaa
    21781 ttttaataat aaacaattta tcaaaaaata taaggctaaa gagatttttc tcctttgtaa
    21841 aacaaataaa ttatgtttct attggagcta tgtttactgt ttacttaggt cttgtatcca
    21901 tacaaggatt gtatgtaacc agttttgata aattcagtgt aaagactgct aaatttgcta
    21961 taggtaattt tattcctgtt gtaggtggat ttgtatctga ctctgtggat attttattat
    22021 cttcatctca gcttataaaa aatatatttg gaggaatagg gcttatctta cttgttggaa
    22081 tttgtttact tccagtaata aaaattttat cagtaatagt agtgtacaaa ttagcagcaa
    22141 taattgtaga gcctgttgga gaggatggaa tatctaattt tttaaatgaa gtggcaaatt
    22201 taatgataat aatgctagca tcagtaattg ctataacagt aatgttcttt gtaactgtag
    22261 ctatcttgac ctcgataagt gtcgtaagtc aagggtaatt tatatatcag tgaaaaataa
    22321 ttacatttaa tctaatgttt ttagagagga ggatgctatg ttagagggca taaaggcatg
    22381 gatagttagt gttttgatag gagcatttat agtaaatata gtagatatga ttttaccaag
    22441 ttctaagata aaaccttatg tcaacctagt tttaaacttt atgtttgtat ttattgtaat
    22501 aactccagta gtaggatttt tttcaaaaga tatgagttta gaagatagaa tattaaaatc
    22561 tatgggaaac tacaacaagc agtatgtaga tagtacaaat gctttggcaa aagagactgg
    22621 aaataatagt ctatccaagg gatatgagga tgggttaaaa gaagtactta aattaaaact
    22681 tgatgaatat ggttatgatt tagaagatat agagcttaat ggggcaaata taaataatat
    22741 aaaaataaaa gaaaagaata atagtgcaaa aagtaataac agttccaatg aagaaaataa
    22801 aaataatagt actaaaagag aggaagaaaa cataaactct aatgacaaag aaaattctaa
    22861 acaagtcttc aaaaaaggta cagagtatgg gttgaaccta aatgaagaaa aattaaaaaa
    22921 cgacttaata aaggtgctgg atgtttctat agaagatata caaattgata aataggagtt
    22981 gggagaatgt tgaaaaactt aaatgacaaa gataagagaa aggtatattc actaataact
    23041 atagcaggaa tatgtgtggt ttcattagta ttattatctt gttttcctag tagcaaaagt
    23101 gataaacaag ttggaaaaac agagactaat aaaaatgctg aaaagcaagt cactaaaaaa
    23161 caagaaaaag atgatttaga gtcaaaatta acagcaatac tatctaaaat tgatggtgca
    23221 ggagacgttg atgtaatggt tacatttgaa tcaagtgaag aaatacaacc tgcttttaat
    23281 tcaaataata caacagaaac aacagaggaa aaagatgcac aaggtggaga aagaacagtt
    23341 acgacttcta gtgaaaataa aacaatgata acttcaaatt caagtgaccc tgtagttata
    23401 aaaactacag agccaaagat aaagggagtg atagtggtag caagtggagc aagtgaccca
    23461 agtgttaaag agacacttta tagtgcagta caaacatcat tacaagtagc tggtcatcaa
    23521 gtagaaatat attctaaata aatacatata accgggggga taaatgaatg aagtttaatt
    23581 ataagggaag aggatttgta ataataactt taactgcaat gttagtggta gtaggaacag
    23641 tgaattatca actaagtaag aaatctttat tagaaacatc aaaagagttt aaggcatatg
    23701 aagaagcaca gttgcaaaaa aatactgatg atagtgatag tagtaagaca gaggattcta
    23761 gtaatgtaga taaacaaggt ggtaaggaaa gtgctgatat tgatatagtc gatagcaaag
    23821 ctagtaaagt aaaagaaaag gcaactgaga caagtaagga aataaaagct caattatcat
    23881 cagagaaaaa tatgaaaaag gcatcttata ttttagatat gaaaatgaat agagaaaaac
    23941 aaagaaatga gttagttcaa gatttaaatg aaatgataaa taatccatct acaacagaag
    24001 aatctagaaa agaagcttct aatatgaaat taaatatagt taaaattcaa gaaaaagaac
    24061 ttcaaataga aaaccttttg agtacaaaag gatatgaaga agcgttagtt tatataagcg
    24121 ataacaaagt taatgtagtt gtaaatgaag ctaaattaga aaagaaagat gcagcaaaaa
    24181 tatttgattt agttgcagaa caagccaatg tgaagtatga aaatattaaa cttacaaata
    24241 ataatagtaa taagtaaagt ataaacctca gaattaactg aggttatttt cttgcaaagt
    24301 agacttgtat ttggtattat tatacttata aaaatagttc cttaaaatca ggaggtaagt
    24361 tttaatatgg aagataataa atttggacaa gtaaaaatat ctaatgatgt aatagctaca
    24421 atagctggtt tagcagcatt agaagttgaa ggcatagaaa ctacagcaac attaacagat
    24481 aagttgttaa aaaataatgg agtaaaaata caaatcgaag aagaggatgt taatttagat
    24541 gtaatggtta cgataaagta tggaatgtca ataccagata cagcttttaa agttcaagaa
    24601 aatgtaaaaa atactgttga gacaatgaca ggactgaagg tttctcaagt aaatatacac
    24661 attcaaggaa tcagctttaa gaaggataaa gttgataaag aagaagcaaa agcaactaag
    24721 aaaaattaat attagccctc tgaaaagtca gagggttttt tgctggtaat tgattttata
    24781 tggataatta aacttaaagg agaattttga ttgatgaaaa aagatagggc acaaaagagt
    24841 acaacaagag aatatataat gaaacttata taccaaataa atattaataa agaagatttt
    24901 gaaactttag aagataaagt agataatttt ttaaaagata attcagaaca tattataaat
    24961 agatataaag aacttgcact tcaatactca aaaaatacaa atttaaagtt agaagatact
    25021 gaaattgaag atgttataga caagaaatat ataaatacag tatgcaaagc attaaaagaa
    25081 aatcatgaca aaatagatga gttaataaat aagcatgcta aaaactggac agtagataga
    25141 atgccaaagg tagatgtttc tatacttaga ttgtctgtgt gtgaaatact ttatttagac
    25201 actcctaata aagtatcaat aaatgaagcg gtagaacttg caaaaatata ttgtgatgat
    25261 aagtctccta aatttataaa tggtatattg ggaagtgttg ttgatgaaat tgggaaataa
    25321 tataataatt ggaattgata ctagctgcta tactacttct atagcagcta tctctttaga
    25381 taagaaagtt atattcaatg aaaaaataat gttagaagta agggataatt caaaaggttt
    25441 aaggcaaagt gaagctgtat ttcaacatat caataattta gggattctta gtgataggat
    25501 aaaatctttt aaagataagt ttaatgtaga aggagtttgc tcatcaaaaa aaccgagacc
    25561 tgttgaaaac tcatatatgc ctgtattcaa tgtaggtcat aattttggaa aattattgtc
    25621 tagtatatat ggttgtaggt tttatgagac tactcatcaa gagaatcata ttgaagcaag
    25681 tttattaaat agtaaattaa aaaataataa taaatttatt tctgttcata tgtctggtgg
    25741 tactacagag atacttttaa caagcaaaca agatagtcat cacaatgtat gtgatactaa
    25801 tttaggtaaa attgccaaaa taagtattaa aaaagatgat aaaagtaagt tatacaataa
    25861 ttttggatat aatatagata taattggagg aagtaaagat attagctttg gtcaactcat
    25921 agatagagta ggaattaagc ttggatataa atttccttca ggaaagtatt tggatgaaaa
    25981 tgctttaaat tgtaatctta aaatagaaag tggtctgaaa acttctgtaa gagatgggta
    26041 tatgaattta tctggattag aaaatcaggt aaataagatt ataaatgata atggagataa
    26101 tactaatcaa aaagaataca tatctaaatt agtattagat tcagtagtta gaaatatgtt
    26161 taaatcttta gtatatttat gtgaaactta taatgtaaat gaagtagtat ttgctggtgg
    26221 agtttctgca agtaagtata ttcttagaga attaagcatg aagttaagaa aaaagcatat
    26281 agaagcttat tttacagaac cacaatattc aactgataat gctgtcgggt gtgctataat
    26341 aggattgaat aactttttag gagaaagagt atgaaactaa gagctttaga tataagtgaa
    26401 gcaaactcat atattaaaag aattttaata aacgacccaa tactttctaa tcttaaagtt
    26461 aaaggagaaa tttctaattt taaggttcat agtagtggga atgtatattt atcacttaaa
    26521 gatgaaacat caaagttaaa ctgtgtaatt tttaaaagta attttaatcg caatttaaaa
    26581 ttagataatg gtgtaaaaat tatagctaat ggatatatat cagtctatga aagagatggt
    26641 gcgtatcaat tatacattaa tgaaattgaa atagagggaa taggaaattt acacatagag
    26701 tttaatagat taaaggaaaa acttaataaa gaaggattat ttgaccctaa atacaagata
    26761 cctataccta aaatgccaaa ctcaattggc gttataacat ctccaacagg tgctgttata
    26821 agggatataa taaatgtaat aaaaagaaga tatccgaaag ttaatataaa gctttatcca
    26881 gtaatggttc aaggagataa atcagctgaa gaaatctgtg aagcaattag atttttcaat
    26941 catatgaaga atgttgatac acttatagtt ggtagaggtg ggggttcaat agaagaactt
    27001 tggtctttta atgatgaaat ggtagcaaga gaggttttta attctcaaat tccgataata
    27061 tcagcagttg ggcatgaaac ggattttact atttgtgact ttgtgtctga tatgagagcc
    27121 ccaacgccat cagcagcagc tgagattgct actccatcat tggatgatat aaactataaa
    27181 cttggaaaca taaaaagtag gatgagtaag tctcttacaa atcaaataga gctagaccaa
    27241 tataggttag aaacagtatt taataagata aataactatt tagattcgta cacaataaaa
    27301 gataaagtta tacaattaga caaaatatat gataaaataa tttttggaat agaaaataat
    27361 ttaaaattag aagatgaaaa attagtaaaa attggagcat tactccataa tttaagtcca
    27421 ttagctacta tggatagagg ttatagtata actcaaaaaa atggaaaagt aataaatagt
    27481 ataaaaggat taaaaataaa ggatagtata gatatagtat taaaagatgg aaatttagaa
    27541 tgtatgatag ataaaattga aaataaagag ggatagtatg aatttaacct acgaagaagc
    27601 ttataaaaga ttagaaagta ttttaagtga attagaatct aaaaatgcta gcttggatga
    27661 atctttaagc ctatatgaag aaggtataag cctttataaa cattgtaata agcttttaga
    27721 tgatgctaaa ttgaaaataa gtaaatttaa tcaattagga atagaagaag actttaaaat
    27781 agaggaggaa taaaattgga atttaaacaa tgtctaaaag aaaaagcaag ttttgtagaa
    27841 aaagtactta aagaatatat gcctaaagaa gaagggtatc aaaaaactgt tattgaagct
    27901 atgaactata gtttaagtgc tggaggtaaa agattaagac caatacttac attggaggct
    27961 tgtaaaatag ttggaggaaa tgaagatgaa gctattcctt ttgctattgc aattgaaatg
    28021 atacatacat attcactaat acatgatgat ttgccagctc ttgacaatga tgatttaaga
    28081 agaggaagac caacaaatca taaagtatat ggagaagcta tggggatttt agcaggagat
    28141 gctttgttaa actatgcttt tgaagtaatg cttgcaggct caatcaataa agaaaatcca
    28201 gaaaagtatc taaaagctat aaatgaaatt gccaaaggtg ctggtatata tggaatgata
    28261 ggtggtcaag tagtagatgt agaaagcgaa aataaacaaa ttgaaaaaga aaaattagat
    28321 tatatacata tgaataaaac tgctgcaatg atggtaggct gtatgagagc aggagctact
    28381 ataggtggag caaattctga acaaatggaa gaaataacta aatatgcaaa aaatatcgga
    28441 ttatcattcc agatagtaga tgatatacta gacatagtag gagatgaagc taagttaggt
    28501 aaaaaggttg gaagtgatat agaaaatcat aagtcaacat acccatctct tttaggttta
    28561 gataaatcta aagaaattgc acataatttg attgatgaag caaagaaaag tatagaaaaa
    28621 ttatctgatg atgtagattt tttaaaggga ttggctgaat atataataga tagagaatac
    28681 taaaatatac agctaaaatc gaggagggaa aaatggattt tttttcggag atttttaaca
    28741 atggggcttt gggaataagt ctgattgctt gtttcttagc acaatttata aaaatattta
    28801 ctggtaagga aaaaagaatt gagttatcaa gaatacttat ttcaggaggt atgcctagtt
    28861 cccatagttc ttttgttaca agtttagcta cagtggtagg tattgaaaaa gggtttaatt
    28921 ctactgattt tgctataatt accgtacttg ccttaattat aatgtatgat gcagcaggtg
    28981 ttagacgagc tgttggtaaa caagctacta tattaaatca aatggtggca gatatacagc
    29041 atggaaagca tatagagcag aagaaattaa aagaattaat aggtcataca ccactagaag
    29101 tttggtttgg agctttactt ggaatagtaa cagctttaat attgatgtaa attgaaaatt
    29161 tacagaataa aggtgaggat aatatgtata aatatttaga taaagtaaat tctccaaagg
    29221 atataaaaaa tatgagtata gaagaaatgg atttacttgc aaaggatata agaaagttct
    29281 tagtaaaatc tgtttcaaag acaggaggac acttagcttc taatctagga gtggttgagt
    29341 taacattagc acttcataaa gtatttgata gccctaaaga taagattgta tgggatgtag
    29401 ggcatcaatc ttatgttcat aaaatagtta ctggaagaaa agattgtttt gtatctttga
    29461 gacagtttaa tggactaagt ggttttccaa aggagaatga aagtcctcat gatatttttg
    29521 atacaggaca tagcagtaca tctatttcta tagctacagg tattgcctgc gctagggata
    29581 taaaaaaaga aaactatagt gttatatctg tgataggaga tggttctata acaggaggta
    29641 tggcacttga agctttaaat caattaggat atatagatac caatatgata gtaatcctta
    29701 atgataatga gatgtccata gataaaaatg ttggaggaat gtctaaatat ctgtcaagta
    29761 ttataagaaa ctcaacagtt gagaaaatga cagatgaagt tgataaaatt ttaaatgtta
    29821 cacaaacagg tgaaatttta tctaagactg cacatagatt taaagataaa ctaatgtata
    29881 gcttttctcc tcaggactgt tcattttttg attcattagg tataagatat tatggaccta
    29941 tagatggcca taatactaaa gaactaatag atatattgag aaaagctaaa cacaaaaaag
    30001 ggcctgttct tttacatgta attacgaaaa aaggaaaagg gtacagattt gcagaagaac
    30061 aacctgataa atatcatgga gtatcaaagt ttgatataaa gacaggtgtt acatctgcaa
    30121 aagttaagtc tatgtcaatt agtgttggag aaaaacttgt tgatatggct aataataatg
    30181 aagatatagt agcaataaca gctgcaatgc catctggtac agggttaaac ctgtttgaaa
    30241 gtgcatatcc aaaaagatat tatgatgttg gtatagctga acaacatgcc acaggatttg
    30301 cagcaggtct tgcaaaaaat ggtatgaaac cttactttgc tgtgtactca tcatttttgc
    30361 aaagggcata tgaccaagtt attcatgatg tatgcataac aaaaaagcca gttacttttc
    30421 ttatagatag agctggatta gttggaaatg atggagaaac tcatcatggt atgtttgatt
    30481 taagttactt aaattctatt ccaaatattg tagtaatggc tccaaaagac acaagagaga
    30541 tggagcttat gatggatttg tcattaaaat tagattgtcc actagcaatt agatacccaa
    30601 gaggaagtag ttattaccta gataagggag aatatggaga gattgtactg ggtaaatatg
    30661 aggtattaga tgacggtcaa gatacagtca tactttgtat tggaagtatg gtaaaacatg
    30721 ctttagaggc taaagaaata ttatcaagag aaggaataaa tccgacaata gttaatgcta
    30781 gattcttaaa gccaattgat gaaggtatgt taaaagcatt attaaaaaat cataaaaatg
    30841 tagttactat agaggataat attgtaactg gaggatttgg aagtagaata aacaagttta
    30901 ttatagataa tgaatataac gtaaatatac ttaatatagc aataccagaa gaatttgtaa
    30961 aacatggcaa tatagatgaa ttatatgatt ttgtaggatt atcgccaaaa agtattgctg
    31021 ataaaataag gaaattagtt attgagtaaa aatctaatgt agatattgta aattaaaatt
    31081 tatataaaat atagaattta tcaattagaa taaatatcaa gtgtgttact tcaagctact
    31141 ttagttatca ttaaagtagc ttttaacaga aaggtaattg tatgaaaaaa agaatagatt
    31201 tattattagt agaacaaggg tactttgaaa gtagagaaag agccaaaaaa gcaataatgg
    31261 ctggattggt ttttgttgat aatcaaaggt gtgataaggc tggtacagaa gtaaaagaag
    31321 attgtagtat agaagtaaaa ggaaatccaa taccatatgt cagtagaggt ggtttaaagc
    31381 ttgaaaaagc aatgaaaaac tttgatttga ctattgatgg aaaggtatgt atggatatag
    31441 gggcatccac aggtggtttt acagattgta tgctcaaaaa tggagcaata aaagtatttt
    31501 ctatagatgt tggttatggt caacttgcat ggaaattgag acaagatgat agggttgtgt
    31561 gtatggaaag aactaatata agaaatgtta caatagaata tacaaagcag tttgctgatt
    31621 ttgcgtcaat tgatgtgtct tttatatcgt taaagttagt acttccaaag gcaaaggagt
    31681 tagtacgtca tgatggggaa gttgtcgctt taattaaacc tcaatttgaa gcaggaagag
    31741 aaaaagtagg taaaaaagga gtagttagag aaaaatctac acatatagaa gttataaaaa
    31801 tgatttctga tttctcagtc gaaaatggat ttgagatttt agggttagat ttttctccta
    31861 ttaaaggtcc tgaaggtaat atagaatatc taattcattt gagaaatgga aatgaaggat
    31921 atgaatttga tggtgagaca tacaataaca aaatagtaga agttgttgaa gcttctcata
    31981 atttagacaa ataggttaaa agggggctta gatttgatcc tcgaattata tatgaaaaat
    32041 tgtgccttag ttgaagaact aaggttgaat attgataaaa acttaaatat acttacaggt
    32101 gaaactggtt caggaaaatc tataataata gatgcacttg gactttgttt aggtgataaa
    32161 tatgataggt cttttttaag aaaaggaaca gataagggac ttgttgaggc tgtatttttt
    32221 tcagacaata gatatcttaa aaaaatatta gaagaaaatg atataagtat ggaagatgat
    32281 aatttattgg taataactag gttgatatac tcagatggta agagtactgc tagagtaaat
    32341 ggaaggactg ttaaagtgtc tcttcttaaa gaaattgcat ctacacttat agatatacat
    32401 ggtcaacatc aaaatcaagc tttgttcaat aaagatactc atttaaaatt tctagacctt
    32461 tttggagaaa atgaattgga agagtttaaa attgcttata aaaatgtgta ccataagtat
    32521 agtgaagtaa aaaaagcttt aaattgcttg acagaaaata aagatgagat gcaaattcaa
    32581 cgagaaatag atttattaag atttcaaata aatgaaattg aagctgcaaa tctaaataag
    32641 aatgaatatg aagatttatt aaaacaaaga gaagtttata gaaatagtga aaagatatat
    32701 aataatctaa attcgagtta tagcaagtta cataatggtg agtataatgt tattgaccta
    32761 ataggtcttg catctaagga acttaatgac atatctaaat atgacagtgt tttaagtgaa
    32821 tatagtgata ctgtagaaag aattatgtat gagttacaag acatatctgg tgagataaga
    32881 aattacaaag ataatataga ctttgaacct tatgagctag agcagattga gcttagaatc
    32941 gacgaaatta ataatttaag aagaaaatat ggagacagta tagatgatat atttgagtat
    33001 tatggaaaaa ttaaagatag attagatgaa atattaaata gagatgaaag agttgaacag
    33061 ttaaaaagca aactgatgaa tatagaagaa gatttaaaaa taaaagccag taaattgact
    33121 aaagcaagaa tagaagtagc aactacttta gaaaaaatac ttcttgatga attaaaaagc
    33181 ttaaatatga aaaatgtaat gttcaaggtt aattttgaaa aaggttcatt tactttagat
    33241 ggagtagatg atattgaatt tatgatatct tttaacttag gagaagatat taagcctata
    33301 tataaagttg catcaggtgg tgagatgtcc agatttatgt tagcgtttaa aaccatattg
    33361 gctgatatag atgatattga tacattagtg tttgatgaga tagatactgg aataagtggg
    33421 atagcagcac agatagttgg tgagaaattg agtgatatag caaagaaaaa acagataata
    33481 tgtataactc atttacctca aattgctgca aatgcagaca ctcattattg tatagagaaa
    33541 gatacttcaa ataataggac gtttaccaat gttagtaagt taaatgaatc tcaacgaaaa
    33601 aatgaaattg ccagacttat agcaggtaac aatataacag aaaaaactat tgaacatgca
    33661 agtgaaatca ttgaattggc taaaaaatgt tagtgaaaaa caagcatttt aataggtgta
    33721 aagaattttt atagaaatgc tttacaccta ttttttatga tgaaattatt ttaaaatatc
    33781 tagtgcctat attgaagaaa agtaggtttg aaaatggaat gaactttgta taaatttgta
    33841 actttgaaat ttctaaatgc ttaagtataa tattatttat taaggtagta gtgaggggag
    33901 gcataaaatg aataaaaaag atactatgca cttaattttt ataattgtaa tttttatttt
    33961 attatggtat attgtggtag cagtaagtga gattaataaa aatattgaaa gttgtagtaa
    34021 caaattagat tatttgtcac aagagcttat gagtactaag tcggatatta gtaatactat
    34081 aaatgaagaa atgtcaaaaa gttatataac aaaaagtatt gacttaaaag taaaaaaaat
    34141 cgagaaaaaa gaatgtacta ttgatgtaga tgttcaatta agtaaacttg gaaaaaatgg
    34201 aaaagtattt tttatgtata aagaagatag tgataaatgg aatgaaactg agatgacaaa
    34261 acatggggaa ttatcatatg catgtgaaat aaagataaat acaggaagtg aatatgatta
    34321 taaagtagtt acaagtggag atatatctga aagttctgat gtacaaaaac tgactaaatc
    34381 tgattatatg cctgaacaac ctatatttaa ttctgggata agagataata gagaatactt
    34441 tattgaaata gtagaaaata gtaatctttt taatcatgag agtgaaaagt caaaaaataa
    34501 agcttacgat aatatcaggt tagaaaaagt agatattatt gtaaatgaag gaaaaaaaga
    34561 cactatatac aaagcccaat tagctgaagg cttagatgat ggcaaaacta ataattcaaa
    34621 tagaaatcaa gtgaattatg aagtaagttt tcctaaaagg gatattgatg acataattta
    34681 tattaaagct aaacttacat acaataatgg agtagaatat acaaaggata taactgaaga
    34741 tataactatg ggattacaag atttagaaaa ataaatacat atttaaataa atattcaaat
    34801 agatttgttc acaaatagag tataaataaa actgtagtag ttttacttat actctattaa
    34861 aaaattataa ttttaattcc atatatctag ccccttcaat tggattataa gtataaagtt
    34921 ctatatcata aaaaccaaac ttttcatata atccttgtgc acttttcatg cttggaagag
    34981 tatctaatct catgtgtgta tatccaattt ttttagcttc tacaatgatt tcttccaata
    35041 gtatttttcc tatttttaat cctctaaatt gatttcttac atataatctt tttaattcac
    35101 atattttacc ttcaagtttt tttaaagcaa cacaacctgc caaattttca tcaacaaatg
    35161 ccaatatcaa tgagcctgaa ggttttttat attttcctgg aagtgttttt aattcattat
    35221 taaagtcttg aaaacataag tctatattta gagaatttga atattcagta aatagaagtt
    35281 ttacgttttc aagattttct aaatcttttt cttcaacaaa ttgtaaagtt atattttgag
    35341 ccattttatc cgccattata taaacatgtt tatataatga cttcacctcc ttgatatatg
    35401 tatatttttc ttaatatcaa ttagatttta ataccattac tttttcacca ccatagtcaa
    35461 gctctccatt aaacttaaat ccaaaatctt tataaagctt aatagccatt ttattgtctt
    35521 cgaatatact aagatatagt tcatcacagt tatattcatt tttaagatga tttacaagaa
    35581 aatctaatga tgcttttcca catcctttac cttgatattt tgaatcaatc ataaatctat
    35641 caagccaaac tctatcatct tctaaacgac catacatagc aaatcctatt aaagaatttt
    35701 catcatatat tccaacaggt acccaagctg ttataaattt agattcagca atagaaagtg
    35761 cattgctttc tatgtaatct aactgacttt tatctacaga caaactaact aaatcgtgcc
    35821 aattatttat gtctgcaatt cttacattta atttcaagat attaccgtcc ttcaaacttt
    35881 ttgttacaat ctaatactat catattatgt attaaaaatc acttattaag attttaaata
    35941 aactttttga atgaataaat tctcaggaaa aaggaattat aaatacataa taatacagca
    36001 taggagtaga tggatatatg aacaaaataa ataaaaattt caaaaatatt tggataatat
    36061 taggagctgt atcgattttt accatggtta taatttttaa taaaaattgt aatgttaata
    36121 aagagactca aatagaagct tttacaatta agaatcatga taaaaaattt gtatatccta
    36181 tgggaaatat aattggagta aaagcaaata cagatggtgt attggtctta ggatatgagg
    36241 aagaggatgt aggctatatt ggaggcatac aaataggtga taatatagta aaaatagata
    36301 ataaaaggat aaaaaatagt caagatgtat cagagatttt gaataagatt aaaaaaagta
    36361 aagttgaagt gacttttgag agaaaaaata agtataaaac agaagtaata gagactaaaa
    36421 aagaaaatgg caagtataaa cttggattat gggtaagaga taaaatatct ggaattggaa
    36481 ctatgacttt ttacgaccct agtatggaaa agttcaaagc aatcggtcat gccataaaag
    36541 attcggatac taatgaacta ttaaagataa agcaaggcta tatatataag ccagaacaat
    36601 taaaaatagt aaaagctagt aatgaaaaag taggtaaaat aaaaggagat tttaatgaca
    36661 gcaatttaat gggtaatttc tcaaataatt cagagctagg tataagtggt aatattacag
    36721 aaaaccataa taaagagttt aatgtagcaa ataaagaaaa gcaattaata gaagttggaa
    36781 gaccgcaaga tgtaaaaata ggagatgcag taattctttt tgaggataaa aacaaaaata
    36841 taacaagcta tgatataaaa atagaaagta tagtatatga taaaggaaat tatagagata
    36901 tggtaataaa agtagtagat gacaagttat tggaatacac aggaggtatc gtacagggga
    36961 tgagtggagc tccaataata caaaataata aaattattgg tgcaataact catgttttta
    37021 gagataatcc gaaaaaagga tatggtattt ttatagatga aatgataaaa ttgtaggtga
    37081 ggcattaaaa aattttatta ttttatcaat tatctaggag gaatataatt ttggagtgtc
    37141 gaatatgctt tagagtagat aattaggaag caattgtgta aaaagtttag ttttctgtaa
    37201 taagaagatg ttttttaatg gggggatttt tagtggaaaa aatcaaaata gttttagcag
    37261 atgacaataa ggatttttgt caggtattaa aagagtattt gtctaatgaa gatgatatcg
    37321 atatattagg catagctaag gatggaattg aagcattaga cttagtaaaa aagacacaac
    37381 cggacttatt aatactagat gtaataatgc cacatctaga tggattaggt gtaattgaaa
    37441 aattgaatac tatggatata cctaaaatgc caaaaataat agtactatca gcagtaggtc
    37501 aagataagat aactcaaagc gcaataaatc taggagcaga ttactacata gtaaagccat
    37561 ttgattttgt tgtgtttata aacagaatta gagagctagt ttctaataga gttacacaag
    37621 ttgagccaaa acctagacca gttcaagaga ctcaaatgac tagaagtgat tttgttaaga
    37681 atgtaggaaa tatagagaca gaaatcacaa atataataca tgaaatagga gtaccagctc
    37741 atataaaagg atatttatat ttaagagaag caataaaaat ggttattgat aatgttgagc
    37801 ttttaggtgc agtaacaaaa gagttatatc caagtatagc taaaaaattc aatacaacac
    37861 caagtagagt tgaaagagca ataagacatg caatagaggt tgcatggagt agaggaaaag
    37921 ttgacacaat aaatcaatta tttggatata cggtacacaa tactaaagga aaaccaacta
    37981 attcagaatt tatagcaatg attgctgata aattaagact agaacatagt atggttaaat
    38041 aaacaagaca taaaaagtaa ggctttttaa ttaaggcatt ggctataaat gcgtattaca
    38101 agcagcgaaa cggtataacc actagggtta taccgtttcg ctattttaat aaatataaaa
    38161 attttcttta ttatttgctt actatatcaa tataataatt ttattatact atggatatag
    38221 tatgtgtctt tacaagttgt aaactgacag tggtttattt tttaatataa atattgactt
    38281 tgatgcaggt aaactttgta tttttaagcg tattatggaa tatgttaaat aaaaaaatga
    38341 tgaaatatag tattgtaaat gccaaagatg caaaacaaac ttaaaacatt tattttattg
    38401 ttaagtaatg ctataatata atgtgatttt aataatgata gtggaggttt aaatatgaga
    38461 gtcgaggccc ctataaaagt agatcgaaaa accaaaaaac ttgctaaaag agttgaaagt
    38521 ggggaaatag cagttataaa tcatatagac atagatgaag ttgctgcaaa ctctttagta
    38581 gaagctaaaa taaaacttgt cataaatgcg gctccttcta taagtggtag gtatcccaat
    38641 aaaggtccag ggatattaac tgaaaataat atactaataa ttgataatgt tggagaagag
    38701 ttatttgaag aattaaaaga aggagaaact atagaagttg tagatggaaa gatatataga
    38761 aaaggaaaat ttttaggtgc aggagaagtt ttagacaagt atgaggtttc acaccaaata
    38821 aaggctgcct atgagaattt agctgtagaa ttggatagat ttatagataa tactatagat
    38881 tatgctaaaa aagaaaaagg atttatactt ggagaagtag aaattccaaa agtgaaaact
    38941 aattatgcta ataaacatgt attgatagtt gtaagaggtc aggactacaa agaagattta
    39001 agtactatgc tttcttatat agaagaggta aagccagtat tggttggtgt tgatggagga
    39061 gcagacgctt taattgagtt tggatatact ccagatgtga ttgtaggtga tatggatagt
    39121 gtaagtgatg aagctttaaa aaaggctagt gaaatagtag tacatgctta tacagatgga
    39181 agagcaccag gtcttaagag ggttgaggaa ttaggcttag atgcagttgt atttcctgcg
    39241 ccaggaacta gtgaagatat agctatgctt atcgcctatg agtataaggc tgagttaata
    39301 gtagcagttg gtacacattc aaatatgatt gattttcttg aaaaaggaag aaaaggtatg
    39361 gcaagtactt ttttagttag actaaaaata ggttcaaagc ttatagatgc taaaggcgtt
    39421 aatttgttat acagaagtaa attaaaaata aagtacatat gggcattaat agcaacagca
    39481 ttatttcctg tgttggtagt tgcatcattg tcaccaggag ttcaacagtt catacaacta
    39541 atgcaattaa agtttagagt attattacag atgtaaattt taggaggata aatatgcata
    39601 ttaatatgaa atattatata gtcactatag gggctatatt tatagctttg ggtataggca
    39661 tgttagtagg atttaattta aataataatc aacaattaag tgaacaacaa gcaaacataa
    39721 taaatgattt ggatgataag tttaatatct taaaagaaaa aaatgataaa cttgacagtg
    39781 acttagcaag tgtaaataga gattatgaag aggcagttaa ttttataaat aaaaatgtag
    39841 ataagatttt agctggttcg ctgaatggta aaagtatagg aataatatcg gctaatgaaa
    39901 atgacgatta tacaaaaaat atagaagaca taataaataa atctaatgga agtattgcat
    39961 ttaatatagt attaaaagaa aatataacaa atccagaaaa gttaaaggaa atgtcaacta
    40021 aactaggtac agatgtaaaa aatgcaaatg atgcagttaa ttatataatt gacaccctta
    40081 aaaaggaaga tgcaagtgac attttaacat atcttcaaga actagatgta ataaagttta
    40141 actctcttgg aaatacatat ctaaaatatg attctgttgt aatagctggt ggaaatgatg
    40201 caaaagacag tacaaaacag tttgaaaaaa tagaaaaatt tgtagtttca aaacttaaat
    40261 cagagaataa atatttagta gaagttcaaa atacaggagt taaaacttct tatgtagaac
    40321 tatattctaa aaacaaagtt gcaactatag acaatattga tgaaggtata ggaagtatat
    40381 ctctagctat tcttctacaa caaggtaata tagttggtaa ttttggtaga ttggatactg
    40441 caacttcatt gttgccatct attaaataga aataatttta aggagagaaa aaatggattc
    40501 ttatataagt ataataatac cagcttataa tgaagaaagt agaataaaat atacattaga
    40561 aagcatattg gacattaagc aaataaatga aataatagtt gtggatgatg gttcaattga
    40621 caatactgct aaggttgtat ctgagctaga aaatgaaaag attaaatttt ttaagttaga
    40681 taaaaataga ggtaaaggat atgctttaaa ttatggtatc aaattagcaa tgaaaaatgc
    40741 agatattata ggttttctgg atggagattt aggaagctct gctaaagaag ttgaaaaatt
    40801 aatagtacct atattaaatg gtgaggcgga tgttacaata gccaagtttc ctcctgcaaa
    40861 gagaaaagga ggtttgggat ttgtaaaagg tttagctaaa aattctgtgt ttgagatgac
    40921 tggtgttgag ttagatgcaa ctttatcagg tcaaagaata tttaaaagag aagttttaga
    40981 aaagtttgat gaaatacctt ttggatatgg agtagaagtt ggaatgacca ttgatatatt
    41041 aaagtatgga tttaaaatta aagaagtatt agtaaatatg actcataatg aaacaggaag
    41101 aaatttaaaa ggttttattc atagagggaa acagtattat cacataaaaa aggttttagg
    41161 acaaaaaaag aaagaatgga ggtaatatct tagtgaaaga ttatatactt tataccattt
    41221 tattattaac tggattattt ggaacctatg ctgtaattcc actatttaaa aatttattga
    41281 taaatggaaa tgtacttaga ccaaactata aaaaagatat gataccagta agtatgggaa
    41341 ttgtattttt gcctatgatt gtaatcaatg gaataatact tgctttcttt actacagaat
    41401 ttaaggattt agcgtatata tttatgttta tgtttggtat gatatccatg ttttttgcag
    41461 ggatactaga tgatgtcatt ggaaatagag atgtaagtgg tttaaagggg cattttaaaa
    41521 gtttatttaa aggaagtctt acaacaggag gttttaaagc tttatttggt ggatttgtag
    41581 ggcttatagt ttctgttgct atatcaaaag acataattga tataatagta aatacactaa
    41641 taatagctct atcaactaat ttaatgaatc ttttggattt aagaccagga agggcaataa
    41701 aagcatattt attcataatg gtaattatat ttttaacatt gacaggattt gttcaagttc
    41761 ttccattact tatagtacca aatgtacttg catactttaa ttatgattta aaagcaaggg
    41821 ctatgatggg agatactggt tcaaacgtcc ttggaatatc tattggaatg ctcatttctt
    41881 ttgggtatcc atttaacatt agattaggat ggttaatatt tgtagttatt atgcatatat
    41941 tcactgagaa atactcatta actaagataa tagaaaaaaa taaactatta aattttatag
    42001 ataaattggg aaggtagtat tatgataagc aaaagagtgg ggattgttga atcaatagta
    42061 agtcaaactg aaactctaga tgatataaga gtaaatataa atggaaaaat acaaagggca
    42121 tataattatc ccaaaatatc tggaactata aatataggtg atgaagtggt tttaaataca
    42181 acagcagtag aactgagctt aggtacaggt ggataccatt ttgtaataac taatttaaat
    42241 aatatagaat ctactttaac tgaaggtggg catataatga aacttagata tacacctctt
    42301 caaataaaag tggattctgt tgaggaacaa gaaagtattt atcatgataa atttgcgaat
    42361 tttaaaggat tagaaggtct ttctgttgta gtagggactc ttcatagtat gttaactcca
    42421 tttgcagctt catttaaaag aaataatcca aataaaaaat tagtatatat aatgactgat
    42481 ggagcatctc ttccaattta tttaagtaaa aatgtggaca ctttaaaaga aaaaaaatta
    42541 atagatagta cgataactat aggaaatgcg tttggtggag attatgaatg tataaatata
    42601 tatactgcat taattacagc aaaagaaata ctaaaagcgg atgcagtatt tgtcagtatg
    42661 ggacctggaa ttgctgggac aggaacaaaa tatggattta cagggattga acaaggctct
    42721 attcttgatg ccgtaaaaaa acttgaagga agagcaattg caattccaag aattagtttt
    42781 gctgacaaac gagaaagaca tcaaggtatt tcacatcata gtatgactgt atttaaagaa
    42841 attgtaaatg taaatgtaga cataccaata actatatatg atgatgaaaa attgaacttt
    42901 ataaaagagc aaatcaattt aaatggttta gacaaaaagc ataatataat ttatatagat
    42961 aataataaaa cgaaagagga tttagactat tttaatctaa aagtaaagag tatgggaaga
    43021 aattatgaac aagatgaggc atttttcaaa gctgcaagca cagcagcata ttacttaatg
    43081 gaggtttaag atggtattag aagaaaaaac tattagtagt gatagggttt atacaggtaa
    43141 agtaattact ttaaaggttg atactgttga aattccaggg caaggatatc aaaaaaggga
    43201 gttagtagaa gttggtggag cagtaggaat agttgcaatc acagatgata ataaagttgt
    43261 actagttaag caatttagaa aacctataga aaagccaatc tttgaaattc cagctggtaa
    43321 actagaaaaa aatgaaagtc caaaagaatg tgctgaaaga gaattaaaag aagaaactgg
    43381 gtatagtgca aaaaatatta agctaataca taaatttttc acttcagcag gtttttctaa
    43441 tgagataatg tttgtatatt tagcaacagg tcttactcca ggagagaata atttagatgc
    43501 agatgagttt ttagatgtct atgaaattga gcttgaagaa gcatataaca tggtattaaa
    43561 aaatgacgtt gaagatgcaa aaacatctat tggattatta ttagtaaaag atatgtttaa
    43621 aaattaatat ttataaaatg aataaccctt tgtcctaaag catattattt tataaaggac
    43681 aagggggaat taaattgaga agaacatata gaaaaaatga ttttagagaa ttaaatagac
    43741 aaataattat tataggattg ttgtttatga tgtctattgt tgttgggtct tacataaata
    43801 aaatattgcc aggttctagt aacaatatat taaacaatat aaatcctgct gtagagtatt
    43861 ataatctaaa tataagcata aaagatacag tgatacaaaa tttaaaatca gatgcaatct
    43921 ttatgggctc aatagctcta ttaagtctat ttgtagtaac aattccagca gtgttggtag
    43981 cttttgtatt aaaagggatg tcaattggtt atacaataaa tagttgtata ttggcattaa
    44041 aatttaaaag tataaaaatg attttaataa tattatttaa aaatttgatt attattccat
    44101 gtgcaatcat attagcatta attagtttaa gttattttaa agaaatggtt tatgaattta
    44161 aaaagaaaaa tagaaaaaat atgcaatttt taattaagag gtatatacta aatattataa
    44221 ttataatagc actatcattg gggttgcaat taatattaaa tactgtaagt attggtatta
    44281 ttaagttcct agctaaataa aggagtttat aatggatatt atagagggat atatagatta
    44341 cataaaagat aaaaaaaaat tatcagagaa cacagtggca tcatacttta tggatataaa
    44401 aaaatatatg gaatatataa atcaaaaaag cattaaacta gtagatatag tagaaaatga
    44461 tattataagt tacttaataa agttggaaaa agataatgta tcaatagcta caatagcgag
    44521 gatgatatcc tctataaaat cttttcatga ttatttattt ttaaatcata tatgtacaaa
    44581 taatcctgca aaggatataa aaaaacctaa aataaaaaaa gaaaatataa atatacttac
    44641 agaagaagaa attgaaagac tattaaattt tccaaagtta acaacaccta aattgattag
    44701 ggacaaggct atttttgaag tattatatgg tactggtata aaagtatctg aattagtaga
    44761 gatgaatata gaggatattg acctagatat tgattatata tattgtaatt catgttgtaa
    44821 aaatcaaaga gtgataccac tttgtgatat tacaaaactt tacttagaaa agtatctaaa
    44881 agaagcaaga cctaaaatgg ctgtagaagg tgaaaaatca ttattcgtaa gttcattagg
    44941 tcaaaggttt acacgacaag gtctttggaa agtcataaaa aaatattcta atctagccaa
    45001 tatagataaa aatataaatc ctacaatgct tagacattca tttgctattc atttgttaaa
    45061 tgaaggtgct aacattgctg ttgtaagtaa aattttagga aatgttaatt tatctagttt
    45121 gcaagtatat ttaaatcata tagataaaaa cgtgagaaga gaaataaagg aaaaacatcc
    45181 tagaaatgat gttgatgtag aattacaaaa agcagaagct aaatagacta tatagcaaat
    45241 tttataattt aaaaggagta tatttatatg agcagagtaa tttggattgt aattgatagt
    45301 gttgggatag gagcattacc tgatgctgaa aaatttggtg atagtaagga tgtaagtacc
    45361 cttggaaata tatttaagga atatccagat attcagattc ctaatatgag aaatttaggt
    45421 ataggaaaca tagatggtat agattttttt gaaagtataa aagaaccaat aggttgtttt
    45481 ggaaagtgta aggaaatgtc tcagggaaaa gatactacta caggtcattg ggaaatgact
    45541 ggtataatag ttgacaaacc atttaagaca tttgaacatg gattctctaa ggagataata
    45601 gaagagtttg agaaaaaaac tggaagaaaa gtagtaggaa ataaaccagc ttcaggaact
    45661 gtaataatag atgagtatgg agagcatcaa ataaaaactg gagatgtaat agtatataca
    45721 tcagctgata gtgtatttca gattgctgct aatgaagaag taattcccct agaagaactc
    45781 tataatatgt gcaaaatcgc tagggaaata atgatggggg ataatgcagt agctagagta
    45841 attgctagac cattcatagg taagaaaaaa ggtgagtttg tgaggacttc aaatagaaga
    45901 gattattcac tagacccatt tgaaccaaca gttcttgata atataaaaga atcaggactt
    45961 gatgttttag cagttggaaa aatagaagat atttttaatg gaaaaggaat tacagatgct
    46021 atccacacta aaagcaatat ggatggagtg gatgaaactt taaattatat gaaacaagat
    46081 aataaaggtc taatatattc aaatctcgtt gattttgatt ctaaatatgg tcatagaaga
    46141 gacccagaag gatataagaa agctcttgaa gagtttgata gtagacttcc tgaaataatg
    46201 gctaatatga gagaagatga tattttaata atcaatgcag accatggaaa tgacccaaca
    46261 tataaaggta cagaccatac aagagaatat atacctgtta tgatttatgg caataagatt
    46321 aaaaaaggtt ttaatttagg agtaaaagat acttttgctg atattggagc aactgttgca
    46381 gatatactaa atgtaaagtt gcctaaacat gggtcaagct ttaaagaaga tttattttaa
    46441 actataaaat gataaaaact tagcttaata ggatggagag attggaatgt ttgaaaagat
    46501 agcacaaagt agtaaattta taaattctaa aagtaatata aaacctaaga ttggtttgat
    46561 attaggttct ggactaggtg atttagcaaa tgatatagaa gaccctgtca caattaaata
    46621 tagtgaaatt ccaaacttcc ctgtatcaac agtagcagga catgctggac aacttgtaat
    46681 tggaaaactt gaaggaaaag aagttattgc tatgcaaggt agatttcatt actatgaagg
    46741 atattctcag aaagaagcta cttttccagt aagggttatg aaagaattag gagtcgagat
    46801 tcttatagta actaacgctg ctggaggcgt aaataaagaa tttaaagcag gagatttgat
    46861 gcttataaga gaccatataa actttagtgg aagtaatcca ttagtaggaa aaaatgatga
    46921 cagatttggt gctagatttc cagatatgtc agatgcatat tcttctaaat atgtagatgt
    46981 agttaaaaac tgcgctaaag aatgtaatat agatgtcaaa gaaggcgttt atatgttttt
    47041 tagtggtcca aactatgaaa caccagcaga agtgagaatg gcacaaattt tgggagctga
    47101 tgctgtaggt atgtctactg ttccagaagt catagtagct tctcactcca atataggagt
    47161 tattggtata tcttgtataa caaatatggc tgctggcatc ttaaatcaac cactaagtca
    47221 tgaggaagta atagaaacta ctcaaaaagt taaatcagaa tttatgaatt tagttaaaac
    47281 aacggttaaa aatttataag ttaaagctta ttatatattt tttgaggaag tttataataa
    47341 aatagttaat gtttaatttg aaaagaatta ataaaaagct gtcttgatat agaaagttat
    47401 ttctaataaa ggacagtttt tttataatac tacaacattt gaaagtgttt taaagtttaa
    47461 tatttattta aattattata gattagaatg gagatttcaa ttatgagaat gtatgatatt
    47521 ataaaaaaaa agagagataa cttagagctt agtaaaaaag agataaacta ctttatagaa
    47581 aactattcaa agggagatat acctgactat caagcttctg cactattaat gtcgatttat
    47641 ttaaataaga tgaataaaca ggaaactgta catcttacag aagcaatgat gaactctgga
    47701 gacatgataa acctgtctga ggtagatgga ataaaggtag ataagcatag tactggtggt
    47761 gttggagata agactaccat agctcttata cctttggttg cttcatgtgg agcaccagtt
    47821 gcaaagatgt caggtagagg tcttggtcat actggtggta ctattgataa attggagtct
    47881 ataccaggtt tttcgacaga aatggagata agtaaattta ttgattctgt aaataagtct
    47941 aaaatagcag tttgtggtca aagtgcaaag gtagcaattg cagataagaa aatatatgct
    48001 cttagagatg ttacagcaac tgttgataat atatcattga tatcatcaag tgtaatgtct
    48061 aaaaagttag cttcaggagc tgatgcaatt gtgttagatg taaaaactgg tgatggagca
    48121 tttatgaaga cattagaaga gtcttttgag ttagctaaat ctatggttga tataggtact
    48181 ggtatgaata gagatacaat agggattgta acagatatgg atgaaccttt aggttttgca
    48241 gtgggaaact ctttagaagt tatagaagca attgagacat taaaaggaaa tggccctaaa
    48301 gaccttgttg agctatgtga agtattagga gcatatatgt tggttttatc aaaggtagca
    48361 catgattttg aagatggtgt tgaaaagata agagaatcaa taaaatctgg tactgctata
    48421 caaaaactca aagagtttat agagaatcaa ggtggtaata aagatgtagt agatgattat
    48481 tctttattca aaaaatcaaa gtataaatat ccagttaaat caattaaatc aggttatata
    48541 agtaaaatta aagctgaaga tgttggtgta tcagctatga ttcttggagc aggtagagaa
    48601 actaaagatg atattttaga tttatcagca gggataattt tagaaaagaa agtaggagat
    48661 tatgtaaatg aaggtgaagt tttagcttac atgtattata atgatgaaca aaagctttca
    48721 ttggcaaagg gaagatttat tgattcctac tctattgtag attcaaaaat agaaaaaaat
    48781 aaattaatat atggtattgt aactaaagaa gagattaaaa agttttagaa aattttagaa
    48841 aagtgattat aaaaggccta acatgtcaaa aataatgtta ggttttttat tttttgataa
    48901 actataaatt ataccaaaaa tatatatttt aaaacatttt ttacaatata aataagttta
    48961 ttctacaaga tgattgaaaa ttaaagtatc tagttttata atagaaaatg gataaatata
    49021 cataaggagt agattatatt atgaacttta aagaaaatag attgaaaata gcagtattaa
    49081 taattgttat tttgattatc ttagcaggta tatttgtgtt tatacaaata ggtccttatg
    49141 ataaaaataa caaaaaagat gtaattattg acgttccaag tggagcatct gttggaaaaa
    49201 tatctgacat attatatgaa aataaattaa taaagaatga actattattt aaacttttgg
    49261 taaaggttag caataaagct ccgtctataa aatcaggaac atacttactt aatcaatcgt
    49321 attcaaacaa tgatataata agtcttttag tttcaggtaa aatatatcag gatggtataa
    49381 aagtgactat tccagaggga gctacatcta aagaaattat agcaatgtta gtaagtaaaa
    49441 atttaggaga taaagctact tttgaaaatt taataaaaaa acctcaagaa ttttatgata
    49501 aatttccata tttgaaggaa gatggaataa cctctttaga agggttcttg tatccagaaa
    49561 cttattattt taattcaaag aaacaatcag aagaagatat tttaagcgaa atgttaaaag
    49621 tatttgacag taaatacacg gacaagttta aaaagaaaca aaaagaatta aatatgactc
    49681 ttcaagaagt aatggaaatg gcatcaataa ttgagaaaga agctgttctt gacaaagaca
    49741 gacctataat agcaagtgtg ttttataata gacttaaggt aggtatgcct cttcaatcag
    49801 atgctacaat acaatatata tttgaagaga gaaagaaaat tgtaacatat gatgatttaa
    49861 aaattgattc accatataat agttataaaa ataagggatt acctcctaca ccaatatcaa
    49921 atcctggtat aaaatctatt gaagcagcat tatatccaga gaaaacagac tatttatatt
    49981 ttgtagctaa gattgatggt ggaaataatt atagtacaaa ctatcaagac catttaaaat
    50041 acgttaaaga atataaagaa gcaagggata aacaatcaaa agatacaaaa gcaacaaata
    50101 aagaaaatac aaaaaaataa accatgatta taaaaagtct aacagggtaa gaataatgtt
    50161 gggctttttt attgaaaatt gttattctta gatttataat aaagaaagtg taaatatata
    50221 taacaatatg aatttaaaaa ataataaatt aatataaaac ttgaatattt attattttag
    50281 ggagtgtttt tatgagtaat atagttaatg atttggttga agattatata agagtgacat
    50341 taaaagaaaa agaaggattt ttaaaagatt tagaaattta tgcagaggaa aatagtgttc
    50401 ctataataca taaagaagtt tcagatttat taaaagtctt gttaaaggtt caaaaaccaa
    50461 agagaatttt agaagtagga tgtgcaattg gttattcttc tatttttttt gcaagtatta
    50521 taggaaaaga tgcagatata ataactgttg agagaaatga aaaaatgata gaaaaagcaa
    50581 aagaaaacat aaaattagct ggatttgaca ataacataac tatactagaa ggagatgcag
    50641 aagaaaaact tagtcaagtc caaggtgaat ttgaccttat atttatagat gcagccaaag
    50701 gtcaatataa gctatttttt gatttagtta tagataaatt aaaagatggg ggacttttag
    50761 tatctgataa tattttgtat aaaggtatgg ttgctcatga tgattttgtt gtaagaagaa
    50821 aaaagactat agttaaaaga atgagaaatt atttagatta tatatgtaat tgtgactatt
    50881 taagcacatc attggtacca ataggtgatg gtgtagcact aagttataaa gaaagtaaaa
    50941 gaggtgatgt agatggaatt aaataaagta gaacttttag ctccagcagg tgatttggag
    51001 agattgaaaa tagctataac atatggagca gatgccgttt atataggtgg agaaattttt
    51061 ggaatgaggt ctgcagcgaa gaattttagt aaggaagata tggcagaggg agtagctttt
    51121 gcacatgaaa gaggcaagaa agtattcgta acagtaaata taatacctca taatgaagat
    51181 tttctacaat tagaagacta tttgttggaa ctagaagaga taggaataga tgcagttata
    51241 atagctgacc caggagtgct tagtgtcatt aaaaaagtaa ttccgaatat ggaaatacat
    51301 ttaagtacac aagcaaatac aaccaattat ctaagtgcaa acttctggta cgagcatgga
    51361 ataaaaagag ttgtagtggc aagagaatta tcttttgatg aaatatctga gataagagca
    51421 aaaacacctt tagatatgga tatagaagcg tttatgcatg gtgctatgtg tatttcttat
    51481 tctggtagat gtttaataag caactatatg actggaagag atgcaaacaa aggttcttgt
    51541 gctcaatctt gtagatggca atatcatttg gtggaagaaa aaagacctgg tgagtatttt
    51601 ccaatatacg aagatgaaag gggtacattc ttctttaact caaaagattt atgtatgata
    51661 gagtatatac cagagttaat caaatctggt ataacaagtt taaaaataga aggtagaatg
    51721 aagactgcat actatgtagc tactgttgta agagcataca gaatggcaat agatgaattt
    51781 tacagagccc cagaaaactg gaagttcaat ccaatgtgga tggaagaact aaaaaaaggt
    51841 agtcatagac attttacatc aggtttttac ttgaataaac caacaacaga agaccaaaat
    51901 tatcaatcag catcatatgt tagaaactat gattttatag gtatagttag agaaacagaa
    51961 gatgaagatg gtcttattgt tgttgagcaa agaaataaaa tgtgtgttgg tgatgaaata
    52021 gaagttatgg gaccatataa agaaactatg tttactaaaa ttgaagaaat gtacaatgaa
    52081 gaaggagaag ctatagaatc agctcctcat cctagacaaa tagtgaagtt aaagctatca
    52141 gtaaaagttg gtaaagatta tatgcttaga aaagttatag aagaaaaggt tgaagaataa
    52201 taaaaaattg ataaaaatag tattagcccc ttagaaattg tcaataatga aattatctaa
    52261 ggggtgattt catgtcaaaa aagaagactc catttttgaa aaaagtggga aagagaagct
    52321 ggtgtatatt tactataatt ttaataattt atagtgtttt aatttatagg ctagttgata
    52381 tacaagtatt aaaaggtgat aaatacaaac aaagtgttga atcacaaagc gttgagaaag
    52441 tcgagttaaa tagtggaaga ggaataatct atgatagaaa caacaagaag cttacagata
    52501 caagtaaatc tcaggtatta attgttgaaa aagaaaaatt aaataataac tataaaattt
    52561 tggaacttat taagaaagct actaagatga atgatttaga tatatataaa gctgtacaag
    52621 agcaattgac acgccctata atacagattc agactaaaaa tatcgataag agtatgaaaa
    52681 aagaacttga gaaaaatgga ataatggtag aagaaaaaac tatgaggtac gcaaaagatg
    52741 gtttattatc acatacaata ggatatataa aagaagatga taaatcaggt caatcaggaa
    52801 ttgaaaagag tatggatagt gtacttagaa attcaaatga aaagtatata agtgctttta
    52861 aagctggaga tgcaggaaat gaaaaatctc taaacatact aaagggaagt gtaaaaactg
    52921 ttgataataa ggataaagat agacatctaa aaactactat tgattataac attcaaaaaa
    52981 aattagaaca aatactaaat aaagaagaaa atcctacagc agcaataatc tcggaagcat
    53041 ctacaggtga aattcttgca atgtgctcta gacctaattt tgaccaaaat gacatatcaa
    53101 aaagtttaaa aggaaaaaat ggggaatttg aaaatagagt tataaaagcg acatatccac
    53161 cagggtctgt atttaagatg gtagttttat tttctgcact tgaaaatggt gttatagatg
    53221 agaactatac ttacaactgt acaggtaaga ctaaagttgg gaatactaat gaaatactgc
    53281 gatgtaataa aagagatggt catggtttcc aaaacttaag acaagctttt tctaattcat
    53341 gcaatcctgc atttttagat atagctatga aacttggaaa agaaaagata ctcaaatctg
    53401 ctgaaaaatt acatttattt gaaaaggttg atattggtct tgatgaagaa aaaattagag
    53461 aagctccaaa aaacatatca ataagaaatt tagctatagg tcaagaaaat atagaattta
    53521 caccacttca aataaatcaa atgactcaaa taatagctaa taatggaaca ttcaaaccac
    53581 tatacttata taaaagtctt gtggacaata atatgaatac aataaaaact tataagtctt
    53641 caaaaaaaga agaacttatt tctccttatg tgtgtacaca agttaaagaa tatatgaagt
    53701 ctgtatctag gattggtaca gctaaagacc taaaagatat tgaaggtggt tgtggagtta
    53761 aaactggtac agctcaaagt agtttaaata aaaaagctat agaccacgga tggataacag
    53821 gattttatcc tgaagaaaga cctaagtatg taataactgt gttagtagaa ggaactcaaa
    53881 aaggaaataa atctgcaaca cctatattta aggaaatatg tgaaagtata aaataaatta
    53941 tgtactataa aatttaagga tatatcgtaa ctttgatttt agatagaaaa ctttgtctaa
    54001 tgatgtacga tatatccttt taaaatatag tattaacttt cttgaacaag ctctttttct
    54061 agttttttaa gagctttttt ttcgattcta gatacatatg accttgatat atcgagtttt
    54121 tgtgcaattt ctctttgtgt cttatagcca taaggagtta acccatatct taactggaca
    54181 atttctcttt ctctaggagt aagaattttg tttagttgtt cgtaaagttt tccaacttga
    54241 acttttagtt caacttcatc aagaacatag ttagcctctg tgccaagtat atctaaaaga
    54301 cttatttcat tacacactac tctttatatg ttattggtat tactggtctt catgtaattt
    54361 caaatgaacc attaattcaa aagaatctag tttttgttct ttagacttat aataaattgc
    54421 tttatcaatt acagatttta ggagtttatt ttttccaagg gaatctgaat catgataaag
    54481 tgataacaca gttttaatat cttctattat tttagaattg tcttttttaa cagtactcaa
    54541 tctatttttt actgtcttaa ttgaatcttt aatttcttca gttcttgaac ttatattgtt
    54601 ggacctttca ataaatgtat cttcatcata tattccacgt tctaataaat catataactt
    54661 atttttttgt ttacctaatt cttttaattc agtttctaag ccctttaaga ctcgtttttg
    54721 aaattctata ttactatctt tattattttt atctaagtct aaatcacatg cttttaattg
    54781 atattttttt accgtgtctt ccaaagattt taaaatggca gcttcaataa attcaaatcg
    54841 agaactttta ttgcaaccag gatggtaaca aattatatag tcgtggtctg catatggtct
    54901 atatactaat ggtctaccac aatttttgca aatcactatt cctgcaagtg gattttttat
    54961 ttgattacca tagctgacat gaccgttttt tttaagtata ttttgagctt ttttccatgt
    55021 tatttcactt attaaaggtt catgctttcc ttttgcttca atccattcat ctttaggtct
    55081 tagcttaaca gtttttattt tatttggatt tttagatttt ttatagtcct ttttttgcca
    55141 ctgaatgtag ccacaatata ccttattttt tattatattt gtaattgcag aattgtacca
    55201 attagcacct gtagcagttt taatgcctaa gttatttagg tattttgata ttttactaca
    55261 acccatatct tcattaatat ataagtcaaa gatagtccta actacatcag catccttatt
    55321 tggtacaagt attctttctt ttctacctgt tgttacagca tcatatccaa atggagcaga
    55381 agttcctatg aaattccctt cttcaactga ttttattcta cctctttgca ttcttcttga
    55441 tataagtttt aattcttttc ttgccataaa tgcttcaaat tctgaatact cctcatcaaa
    55501 ttcatctgtt aggtcgtatg tttttctagg tgtgatgatt ttggttttac tttctttgaa
    55561 tgtttctaat atgatacctt ggtctttcat gtctccacga ccaagtctgt ctaagtccat
    55621 tactaagact gcatcatatt tattttcttc aacttctttt agaagttcaa gcattttggg
    55681 tctatgtatt atactttcac cagaaactaa ttcttctttt atctcaatta catctaagtt
    55741 ttgttctttt gctagtttta gtagggttga tttatgtcta cttaaagttt caaattcgcc
    55801 ttgtttttct gcctcttcat cagcacggga ttttcttaag tatatggcaa cactcataat
    55861 aagtaatcac actccttatg cactattata tagtaaatca atagagttta aaatatagaa
    55921 aataagcatg tcaaaagtta atttaacttt caacatactt attttctata atattaatgc
    55981 cttataatcc tttaatatca tttagattag tttttgcata ttcattatcc gggttaagtt
    56041 caagcgcctt attgtaagat tctctagctt tattaaattc tgatttactc ataaaaataa
    56101 cacctcttaa attgtaagca tcactagcgt ctattttata agcttcatta tttttatcta
    56161 gatattctaa ggatttatca attgacttta aagcctcatc atatcgttgt aactctatat
    56221 aaatatatga ttgtgtataa tatgcaagtg gatttttatc atcaatttct atagcttttt
    56281 tgatatcaat agcagcttta ttataatcct tatcttcatc tttttttgtt tctgacctag
    56341 cgattttgac ataattagag ctaagagctc ttttaaagtc tttatgccat aataatttat
    56401 attcattatc ttcgattata aaatatctat caaaatttgc agtatcttct ttattttcag
    56461 tgatatactt tatagtatca gtttctttta ttttaacaag atttgtgtac tctttattag
    56521 aatatttgta tttctctact ttattttctt caccaagttt ataatctttt agggtttgaa
    56581 gtttaaataa agtatcttga tattcttcaa atttttctag actgacactt tccttactgt
    56641 ctttacttaa taaattatat gctacttcgt agtctttgat ttctatacta tcaaggtact
    56701 ttttagctac ttctgtagca ctttcttttg gagcacatcc aaccattgat atcataatta
    56761 aaaatgatac taatattgct gttatttttt tactgattat cataatataa tcccccttat
    56821 attgtctctc actaatttta ttttatcacc atattctacc aaagtcatta atttaagaat
    56881 gatatttttc attaatatta tattaagtaa taataatttt taaaatttat ggtaacattt
    56941 tcctgaaaag tattatataa tttaggtgaa aatatttaag agaaggagat attatgaaaa
    57001 ttaaaaaatt attaacaata gggttatctt tatctatatt tattgctagt tgccctatat
    57061 ctgcaaatgc tcttgataaa attgaatcaa ttaaaggtgc agataaatac gaaactgctg
    57121 gtataattgc agacaaacaa aactatacta cagctatatt aattaatgca gacagtacaa
    57181 tggctgatgg attaagtgca agtggacttg caggagctat aaacgctcca attcttttga
    57241 ctaagaaaaa taacatacca aatgctacac ttaaaagatt agaaaaggca aaaaaagtat
    57301 atataattgg aggagaaaac tctattaata aatatactga aactgttcta aaaggcaaag
    57361 gaatagagat taaaagactt caaggtagtg atagaattaa gacaagctat aatgttgcaa
    57421 aagaaataaa ttcaattaac aaagtaaata aagtcatatt gactaatgct tttaaaggag
    57481 agcctgatgc aatgagtgct gcacctgtag cagttagaga taaagcagct atagtattaa
    57541 ctgatggaaa aagtgttcca tttaatacaa ctggtgtaga aagttatgta ataggtggta
    57601 cttcatcaat gaatgacaaa ctagttaagg atactaattc aactagatta ggtgggacag
    57661 atagatatga tactaacaaa aagataataa ataaatttta tagtggagta aaagaatttt
    57721 atatagcaag tggtactgat ttagtgtatg ctcttgttgg ttctaccatt gctaaaaata
    57781 atgctattgt gttagttggt aatgatagta ataaaagtgt attgaaaagt acaattaaat
    57841 taactgctat aggaaatttg agtgatagta tattacagca gtgtttaaat gtaacaaaaa
    57901 atataggcga ttctaatact ggaagagaat atacagtaga agatgctgct aatgcagtga
    57961 aaaaactatt aggtgtgaag aaattttatt acgaacctaa ttattcagaa gatgaagatt
    58021 taatatttct actagataaa aattttgatt tttcaggaaa agagtactat gtatttgctt
    58081 acattaaaca gggtgcagag ggtgatgtta gatactgtgt agctaaaaat gatatgagca
    58141 aagtttatac atatgatgtt aatggtaata tgaaagtatg taatccagat gattataaaa
    58201 ataaaggaag tataacagag gaacaagcaa aacagatagc attaaaagaa tgtgctaaga
    58261 gacataaagt cagtatcaat aacttagtag ttgatatgat agattttaga gatgatatat
    58321 atagtggtaa tgtctatgct gttaaaatca attcaaaaaa tagtaatggt acttttggtt
    58381 ggttttttat agatatagaa actgggaaaa tttataatta aaattagaac ttttaaacaa
    58441 taattatata atttaccata atatgttata atatttttag caagaagatt taacttacaa
    58501 tctatagagt ggagttcatg tacaaaagat tatcctccca acgattcgaa gggaggtgag
    58561 ttcatggata actttttgtt taatgtttta gctagtttaa cagctagtgt ggtagtttac
    58621 ttaatcagta aactattcaa aaaagcaaaa agccactctc gcatgaacta tacccctctt
    58681 aggagacagt tgaaatatgt aaaactgtct
//
LOCUS       DAMJYN010000012        56352 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.012, whole genome shotgun sequence.
ACCESSION   DAMJYN010000012 DAMJYN010000000
VERSION     DAMJYN010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 56352)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56352)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56352
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.012"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            15..995
                     /locus_tag="PC466_000852"
     CDS             15..995
                     /locus_tag="PC466_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDF2768274.1"
                     /translation="MNLKLIWINILNPVFIKNEIKRKKIQIIIFFFINFGLTYSLGLL
                     LYYNKFIDPENFASFMMILPLSSVAIAKFYTEGLNNDMYEFYSLIILFFLIYSLLIVL
                     KLLNLINNNEFIIINLILTFISSLSIIIYSSNKKNLYPVKNIKLGSLLIIYFMISVIV
                     PTSFILILQGAQPNYSGIIKFIFTPITSLTTIYIFFSEEYAWRGFLQNIFFDKFGKKL
                     GVIILGMCWSLWHLPLIFTLYTPEAPILGVILRSIHIVGISIFLGYLYIKTKNIWFCA
                     IIHVLNNSAFLITNSKESTITYHDILIVSMVVLIFYVPFLFTKEYKNNLE"
     gene            complement(1094..2056)
                     /locus_tag="PC466_000853"
     CDS             complement(1094..2056)
                     /locus_tag="PC466_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDF2768275.1"
                     /translation="MNKSWSNLIIKNKDKKVRSGWIIITVMAAFYIFEYYLSTILMEI
                     IRKILIATGDINLKTNYFSEYANWLNDVGLQVVFQILTDSLMIIIPIIVWRFIMKNPI
                     SEMGLHSYRIKKKEGYVGMLLGIFNCTVIFIITITIGGGHVTSWVPKISPLTVSWILV
                     FILVAFAEEILNRGFFMAVLRRCKNIYFIMIVPSVIFGLIHIWNPDVTFLSVINIIII
                     GILFSYMFIKSSNIWMCIGYHFTWNVFQGIIYGMPVSGLQVPGIITTQITHGNLLNGG
                     MFGIEGGILTTFVNLLSFIFVWYYYRDSKYDFVSDKVNVTNIKN"
     gene            complement(2376..3326)
                     /gene="hpdA"
                     /locus_tag="PC466_000854"
     CDS             complement(2376..3326)
                     /gene="hpdA"
                     /locus_tag="PC466_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate decarboxylase activase"
                     /protein_id="HDF2768276.1"
                     /translation="MSSQKQLEGMIFDVQSFSVHDGPGCRTTVFLNGCPLSCKWCANP
                     ESWTVRPHMMFSELSCQYENGCTVCHGKCKNGALSFNLDNKPVIDWNICKDCESFECV
                     NSCYYNAFKLCAKPYTVDELVQVIKRDSNNWRSNGGVTFSGGEPLLQHEFLHEVLLKC
                     HEVNIHTAIETSACVSNEVFNKIFKDIDFAFIDIKHMDREKHKEQTGVYNDLILENIS
                     NLANSDWNGRLVLRVPVISGFNDSAENISDIISFMHKNNLIEINLLPFHRLGESKWIQ
                     LGKEYEYSDKGDIDEEHLEELQDIFLDNGIACYVGHETAF"
     gene            complement(3319..3576)
                     /gene="hpdC"
                     /locus_tag="PC466_000855"
     CDS             complement(3319..3576)
                     /gene="hpdC"
                     /locus_tag="PC466_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate decarboxylase small
                     subunit"
                     /protein_id="HDF2768277.1"
                     /translation="MRKHSDCMNFCAVDATKGICRLSKQMINLDDSACPEIKVMPKCK
                     NCKNFVEANDEGIGKCVGLEKEDWVYSTLNAITCEGHVFNE"
     gene            complement(3580..6288)
                     /gene="hpdB"
                     /locus_tag="PC466_000856"
     CDS             complement(3580..6288)
                     /gene="hpdB"
                     /locus_tag="PC466_000856"
                     /EC_number="4.1.1.83"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate decarboxylase large
                     subunit"
                     /protein_id="HDF2768278.1"
                     /translation="MSQSKEDKIRSILEAKNIKSNFQNKENLSEFNEKKASKRAEDLL
                     DVYYNTLSTADMEFPYWYNREYRKSDGDIPVVRRAKALKAAFSHMTPNIIPGEKIVMQ
                     KTRHYRGSFPMPWVSESFFVAQGEQMREEAKKLASNTADELTKFGSGGGNVTESFGNV
                     VSIAGKFGMRKEEVPVLVKMAKEWVGKSVEDLGFHYEKMMPDYDLKENLMSTLICMFD
                     SGYTLPQGREVINYFYPLNYGLDGIIEMAKECKKAVAGNASGDGLIGMDRLYFYEAVI
                     QVIEGLQTWILNYAKHAKYLESIETDLEAKKEYSDLVEILEHIAHKQPRTFREALQLT
                     YTIHIASVNEDAISGMSIGRFGQILYPWYEQDIEKGLITKEEVIELLELYRIKITCID
                     CFASAGVNGGVLSGNTFNTLSIGGLKEDGSTGANELEELLLEASMRCRTPQPSLTMLY
                     DEKLPEDFLMKAAECTKLGSGYPAWVNNSNGTTFMMKQFADEGMTVEEARAFALGGCL
                     ETSPGCWKQLTLNGKTYSIAGGAGQSAGSGVHFIANPKILELVLMNGKDHRMNIQVFE
                     PHNKPLDTYEEVIEVFKDYYKQAINVLERANNIELDIWRKFDTSIINSLLKPDCLDKG
                     QHIGNMGYRYNATLNVETCGTVTMVNSFAALKKLVYDDKAFTIEEMKDAILNNFGFKD
                     ALEVGNYSMADQVKVDKTGKYDAIYKACLDAPKYGNNDLYADNILKNYEVWLSKVCEE
                     AQSLYAKKMYPCQISVSTHGPQGAATLATPDGRLSGTTYSDGSVSAYAGTDKNGVYAL
                     FESATIWDQAVVQNSQMNLKLHPTTIKGQQGTKKLLDLTRSYLRKGGFHIQYNVVDSE
                     TLKDAQKNPDNYRQLMVRVAGFTQYWCELGKPIQDEVIARTEYEGV"
     gene            complement(6585..7601)
                     /gene="tsaD"
                     /locus_tag="PC466_000857"
     CDS             complement(6585..7601)
                     /gene="tsaD"
                     /locus_tag="PC466_000857"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HDF2768279.1"
                     /translation="MSDIITLAIESSCDETAASVLKNGREVLSNIISTQIETHKKFGG
                     VVPEVASRKHVENIDIVVQEALDKANIGFNDIDHIAVTYGPGLVGALLVGLSYAKALA
                     YTLNIPLVGVNHIEGHLSANYIEHKDLKPPFITLIVSGGHTHLVEVKDYGKYEILGKT
                     RDDASGEAFDKISRAMNLGYPGGPIIDNLAKNGNKHAIEFPRAYLEEDSYDFSFSGLK
                     SSVLNYLNGKRMKNEEIVVEDVAASFQEAVVEVLSNKALKAVKDKGYNIITLSGGVAS
                     NSGLRAKITELAKDNGITVKYPPLILCTDNAAMIGCAGYYNFINGKTHDMSLNAVPNL
                     KINQ"
     gene            complement(7607..8083)
                     /gene="rimI"
                     /locus_tag="PC466_000858"
     CDS             complement(7607..8083)
                     /gene="rimI"
                     /locus_tag="PC466_000858"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HDF2768280.1"
                     /translation="MEDNTKLIVDDIKIEEMTTEDIDEVFEVEKNCFEDYWSKESFRK
                     ELSNEVARYIVAKLNGKIVGYVGIWLILDEGHINNVAVHSDYRGKKIGDKLIKCIVDL
                     CKDNNIASMTLEVRASNKIAQNLYRKYGFKMGGIRKEYYSDNKEDAIIMWNQLKEV"
     gene            complement(8073..8789)
                     /gene="tsaB"
                     /locus_tag="PC466_000859"
     CDS             complement(8073..8789)
                     /gene="tsaB"
                     /locus_tag="PC466_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HDF2768281.1"
                     /translation="MKILGMDTSSMAASVAVVEDDNLICEFTVNNKKTHSQKLMPMIE
                     NMLSMSDLSIKDMDLLAVCIGPGSFTGLRIGMATVKAMAHVNNIPIIAVNSLESLANN
                     INFCDRKICCILDAQKNQVYSAKYKFENGEMIELDGVDVVEFDALVDEIVSTNEEFII
                     VGEAVYKYKDKLENIKNIKIPSPANNVSNAGSLCSLALNKYNKNIDVHTCYTINPMYI
                     RKSQAEVQYDEKMKRLNNGR"
     gene            complement(8789..9241)
                     /gene="tsaE"
                     /locus_tag="PC466_000860"
     CDS             complement(8789..9241)
                     /gene="tsaE"
                     /locus_tag="PC466_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HDF2768282.1"
                     /translation="MAKIYLENENKTREIGYKLGKLLKEGSVICLVGDLGAGKTTMTQ
                     SLADSLGIEDYITSPTFTIINEYEGKIPLYHFDVYRIGSSDEMYDIGYDEYVNSNGIC
                     IIEWANLIEDILPKEYLNIELRYKDEGREMILTPKGEFYKEIVEELIK"
     gene            complement(9380..10420)
                     /locus_tag="PC466_000861"
     CDS             complement(9380..10420)
                     /locus_tag="PC466_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4116 domain-containing protein"
                     /protein_id="HDF2768283.1"
                     /translation="MHLSKKIKKLFLDDKGYYFNSNWEDIHIGIYDTKLGDSLKYITN
                     EYIENMERVKYDYRELKNIENQTDGMCILAIRQNYKALEYVKNQTEELCLEAIKYNYK
                     ALEYVKEQTEYLCLEAIKKDCNALKYVRNKTEGLIIKAISHSSNIDVVSILKALETQT
                     RRICLEAIKKDGRCLAYVREQSEELCIEAIKQNYKALKYVKNQTEKMCIESVRQNGMA
                     LQYVNKQTDKICIEAVKQDGRSLQFVNNKTEEICINAIRYLNKKYNIKDVLSYIDKYT
                     EDICIEIVRQNGKMLMYIKNQTEKMCIEAVKENYKSLKYVKEQSERICKEALKQNHKA
                     KEYVKIAIDDCI"
     gene            complement(10749..11354)
                     /locus_tag="PC466_000862"
     CDS             complement(10749..11354)
                     /locus_tag="PC466_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HDF2768284.1"
                     /translation="MQNTAKRGNMISTRTLVVMSILSAISYLLMFIQAPIPGIFPDFL
                     KIDLSDIPAIFGGMSLGPLVGFGIVVVKNVLQAITATTTGGIGEFANILIGGSYVMIL
                     CYSYKRSGDLKGVLIGFVLGTISMTIIGSLVNYFVMLPLYGQLMGLDAIIGLGSAINP
                     QVHDLFTFVIWMIAPFNVLKAVIISLVTLPLYKKMGNIIKK"
     regulatory      complement(11479..11596)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(11656..12822)
                     /locus_tag="PC466_000863"
     CDS             complement(11656..12822)
                     /locus_tag="PC466_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2768285.1"
                     /translation="MIFIKNGKINTITNGIIHGDILIDEGKIIEIGEDLIAPLDVEVI
                     DASNKLVFPGFIDAHTHLGLWEDGIGFEGADGNEETDPITPQLNPIDGINPMDRTFKE
                     AFEGGITSVCTTPGSANVMGGQCIAIKTCGKRIDKMVIKNPVASKIAFGENPKSCYGQ
                     DDKSPQTRMAIAALLRENLKKAEEYLEDIDMYESHDDEDCEKPEYDIKMESLIPVLRR
                     EIPFKAHAHRADDMFTAIRIAKEFNLKLTLDHCTEGHLIVDELVEEGFPVIVGPSLSE
                     RSKFELRNLTFNTAGILSNAGLDVCIMTDHPVIPVQYLPICAGIAVKHGMKEEKAIES
                     ITINPAKTLGIEDRVGSIEVGKDADLVIWDNSPLEIQSNVLYTIINGKVVYEKK"
     gene            complement(12970..15111)
                     /locus_tag="PC466_000864"
     CDS             complement(12970..15111)
                     /locus_tag="PC466_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011010799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HDF2768286.1"
                     /translation="MDINQILKKEFNLRDEQINNTLKLIDEGNTIPFIARYRKEMTGE
                     MSDVTLREFYEKLMYLRNLQSRKDDVVRLIDEQGKLTDEITQNIEKAKTLQEVEDIYA
                     PYKQKKRTRATIAKEKGLENLALSILENNLDNIEIEAKNYLDEEKEVLSIEDALKGAR
                     DIIAELVSDDAKIRKYIRELALREGMIVSKSATDEKSVYDMYYDYNEAVKSMAPHRVL
                     AINRGEKESFLKVKLEINNDKVLNYIINEYVNDKNFKNKEEIVSSIEDSYKRLIFPSI
                     EREIRNHLTEIAQERAISVFGKNVKSLLLQPPVKDKVVMGFDPAFRTGCKIAVVDKNG
                     KLLDYTTVYPTDPQNDVEGAKKVLKGLIEKYDIDIISIGNGTASRESETFVSEMIKEI
                     DSEVQYVIVSEAGASVYSASELANEEHPDINVSIRGAISIARRLQDPLAELVKIDPKS
                     IGVGQYQHDLNKKRLEEVLDGVVEDSVNSVGVDLNTASYSLLEHVAGISKAIAKNIIA
                     YREENGDFTSRAQLKKVKRLGPQAFTQCAGFMRILEGKNPLDNTGVHPESYDICKKMI
                     EIIGYSLDDVKNKNIGEIDEKIKEIGLRELSEKLEVGQVTLKDIIAEIKKPGRDPREE
                     GIKPILRTDVLKIEDIQEGMTLKGTIRNVVDFGAFVDIGIKNDGLVHKSEMSNSFVKD
                     PMSIVTVGDIVDVKVIGIDLNKKRVALSMKK"
     gene            complement(15255..16362)
                     /gene="prfB"
                     /locus_tag="PC466_000865"
     CDS             complement(join(15255..16286,16288..16362))
                     /gene="prfB"
                     /locus_tag="PC466_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_153309863.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HDF2768287.1"
                     /translation="MLKLQEYRHSMEQMASNLEELRVSLDIASLMKNIQINEEKMNQQ
                     DFWNDNEVAQRVLQENKSLKETLEEYESLKSLLEDIEVLIEIGLEEDDDSVERDIEKS
                     IESMEEKLSEMKIKTLLNGEYDKNNAILSINAGTGGLDAQDWAQMLLRMYIRWSESKG
                     YKVKLLDIISDPEAGIKTATILVEGTNAYGYLKSEKGVHRLVRISPFDPSGKRHTSFA
                     SIDVTPELDENIEVEINPSDLKIDTYRASGAGGQHVNTTDSAVRITHIPTGVVVQCQN
                     ERSQHLNKDRAMRLLMAKLIELKELEQKEKIEDIQGKYSQITWGSQIRSYVFQPYKLV
                     KDHRTNAEFGNVDSVMNGNIDLFINEYLKMNKIV"
     gene            complement(16377..19052)
                     /gene="secA"
                     /locus_tag="PC466_000866"
     CDS             complement(16377..19052)
                     /gene="secA"
                     /locus_tag="PC466_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HDF2768288.1"
                     /translation="MSFMDNLFNMADKKELKKFNKTVDIIDSLEPKFESMADSELKNM
                     TNIFKERLANGESIDDILPEAFAVVREVSKRVLGLRHYRVQMIGGIVLHQGRIAEMKT
                     GEGKTLVATAPVYLNALTGKGVHVVTVNDYLAKRDRDQMAKIYEFLGMSVGVIIHGQN
                     PKVRKEQYDCDITYGTNNEYGFDYLKDNMVIHKEQRVQRGLNYAIVDEVDSILIDEAR
                     TPLIISGPGDKSTHLYSDANTFVLTLKPDDYELEEKDKAVSLTASGIQKAEVYFNVDN
                     ITDISHTELYHHINQALRAHVIMKKDVDYVAKDGEIVIVDEFTGRLMFGRRYSEGLHQ
                     AIEAKEGLKIQRESKTLATVTFQNYFRMYKKLSGMTGTAKTEEEEFKAIYKMDVFQVP
                     TNKLMVREDLPDSVYKSEIGKFNAVAQEIIERHKVNQPILVGTVSIEKSELLSQILKK
                     KGIKHEVLNAKHHDKEAEIIAQAGRLGAVTIATNMAGRGTDIVLGGNPDFLTKREMRR
                     NGFKEEIVNRVDTPIEGIPVKGNEILFEAREEYEKLFEKFKQQTQEEQKQVVEAGGLA
                     IIGTERHESRRIDNQLRGRAGRQGDPGSSRFYIGLDDDLMRLFGSDRISGIVDKIGLE
                     EDMPIEHRILSKSIEGAQKKVEGKNFGIRKHVLQYDDVMNKQREIIYAERKRVLEGED
                     LQEQIQSMTHSIIEEAVTLYTQDKGFDEEGFKEHMYNLFLPKGSIEIPEIEKLNPVEI
                     TEKVYEIAMKIYTSKEEQVGYERMREVERVILLQAVDNHWIDHIDAMDQLRQGIGLRA
                     VGQQDPVIAYKMEGFDMFDEMNKHIKEDTVRYLFNITIETPVERKAVVDVENLSSPSD
                     GTLPTSKTVKKDEKVGRNDLCPCGSGKKYKNCCGR"
     gene            complement(19184..19735)
                     /gene="raiA"
                     /locus_tag="PC466_000867"
     CDS             complement(19184..19735)
                     /gene="raiA"
                     /locus_tag="PC466_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HDF2768289.1"
                     /translation="MNIIISGKQIELTDAIKNKIETKLSKLDNYIHPDTDVKVTVSAR
                     KARQKIEVTIATVNGPIIRAEDMQENLYTAIDVVYDKLSKQLKKYKKRLQDKHKDNKS
                     IRFQDSEINLADEQEDYGDENQELVIQRRKKFSVKPMSEEEAVLQMELIGHDFYMFKN
                     IDSDEIAVVYKRNNGGYGIIEHE"
     gene            complement(20288..20962)
                     /locus_tag="PC466_000868"
     CDS             complement(20288..20962)
                     /locus_tag="PC466_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HDF2768290.1"
                     /translation="MLEIIGMSVEDAKIIEDCGADRIELVSALTEGGLTPSFGLIESV
                     VNSVKIPVNVMIRHHAKSFVYSKEDISIMQKDIGVVKEIGANGVVFGVLDKNNNIDEK
                     NLNVLLKCCDNLDVTFHRAIDESNTIDSVKILKDYDKITNILTSGGKGSIVDNIQMIK
                     NMMLSSNHIKILLGGGLNFNNIEKIKELTKASNFHFGTAIRINNSPFEDIDRQKLKQL
                     VNIISR"
     gene            complement(20965..22017)
                     /locus_tag="PC466_000869"
     CDS             complement(20965..22017)
                     /locus_tag="PC466_000869"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HDF2768291.1"
                     /translation="MNIISNKIDELKEDLLSDIIDIVKIPSVKGESENGFPFGEKVGE
                     ALNKALEISKKLGFKVRNLDNYIGYAEHGDSDDYVCVIGHVDVVHEGDGWKHQPYKGE
                     ETNGRIYGRGVLDNKGPIMSALYGLYAIKELNLKLDKRVRIIFGTNEESGFEDIPYYL
                     EKEKTPIMGFTPDCKYPVVYGEKGMAKIRIKSKINYEEDVYLGFIENMSENVLVTYKE
                     LNIENSNTILDIKVKYDFSYKLKDVLDEIKASFPNSIDIEVISNFNPVYFDKESNLVK
                     KLQLAYERVTSLDGTPVTTNGGTYAKVMPNIVPFGPSFPGQKGIAHNPDEYMDIEDII
                     LNAKIFANAIYELAKE"
     gene            complement(22065..23024)
                     /locus_tag="PC466_000870"
     CDS             complement(22065..23024)
                     /locus_tag="PC466_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase"
                     /protein_id="HDF2768292.1"
                     /translation="MWGMIATWRMALEGITEASEHLEKGMEAGDAVELAVRRVEDYPF
                     YKSVGYGGLPNENCEVELDAAFMDGNTLDIGAVAGIRDYSNPVSIARKLSYEKVNNFL
                     VGIGAEDYAHKNGFERKNMLTDRAKLHYKKRKKETLDKGLSPYAGHDTVGMISLDKTG
                     KMCAATSTSGLFMKKRGRIGDSALSGSGFYVDSSIGGATATGLGEDLMKGCISYEIVR
                     LMKEGKHPQEACDIAVNELDKQLIKRRGKAGDLSLVAMNNKGEWGVATNIVDFTFSVV
                     TKEESPAVYISNRVDGKTIHKVISNEWMEAYEARIKAPIEVSE"
     gene            complement(23120..23638)
                     /locus_tag="PC466_000871"
     CDS             complement(23120..23638)
                     /locus_tag="PC466_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/betaine/sarcosine/D-proline family
                     reductase selenoprotein B"
                     /protein_id="HDF2768293.1"
                     /translation="MKKIVMILDQIQAGAGGKEKSNIPPAGKSSPLGPGVMMEQFLNE
                     SKVIATLFCGDEFFVNNEKEVTSKMIAMVKKLNPDVVICGPSFNYENFSKMSAILSKN
                     INDKTDIPAFAAMSEENIDVINEYKNDICIVKTPKKGGIGLNDSLNNICKLAKAIANK
                     EDITLMKEEFCY"
     gene            complement(23649..24983)
                     /gene="celB"
                     /locus_tag="PC466_000872"
     CDS             complement(23649..24983)
                     /gene="celB"
                     /locus_tag="PC466_000872"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HDF2768294.1"
                     /translation="MNRLERILMPLAEKIGKNKLLIAIRDGFLISSPLLIIGSLFLLV
                     ANFPIKGWNEFVGQIFGPDWAVKLQQPTVATFEVMTLLAVLGIGYSYAKQIDVDPIAS
                     AAVAIVAFFIVTPFVIPYTPEGTESVYMVTGIPLGWMGSKGMFVGMITAITSVKLFAA
                     VVKKGWTLKMPDGVPPTVSKSFAALIPSAIVMVVFFLVKIAFEATPYGSIHEFIFKFL
                     QMPLLKLGNSLGAMAIAYIFLHLFWFFGINGSSVVGAVYNPILKILSAENLAAFQAGS
                     KIPNIITGQFQDMFATFGGAGSTLSLVIAMLLICKSKRIKSMGKLSILPGIFGINEPL
                     IFGLPIMLNPILLIPFAIVPTINIIIAYFCMSAGLVPLTNGVQLPWTTPIIFSGFLTT
                     GWQGAVLQLVLLILGIFMYIPFIKMLDKQYLREENETVEEEDDDISFDDLVL"
     gene            complement(25022..25348)
                     /locus_tag="PC466_000873"
     CDS             complement(25022..25348)
                     /locus_tag="PC466_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2768295.1"
                     /translation="MKRKVYLFCSFGMSTSLLADKMQKVADEHNLPIEVEAFPIAEID
                     KIVEEKNPDCILLGPQVKYMLKELKPKFEAQGKLIDIINEVDYGTMNGEKVLKLAIKL
                     IKSKQA"
     gene            complement(25373..25681)
                     /locus_tag="PC466_000874"
     CDS             complement(25373..25681)
                     /locus_tag="PC466_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HDF2768296.1"
                     /translation="MEEIVLKIIIHAGNAKSMLYEALDYAKENDFKKADELIENANEE
                     ILKAHKVQTELIQKEAGGDKSDISILLIHSQDHLMTCMSERNLIKEMIMLRKEIQKLK
                     "
     gene            complement(25822..27735)
                     /locus_tag="PC466_000875"
     CDS             complement(25822..27735)
                     /locus_tag="PC466_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDF2768297.1"
                     /translation="MICLNKRQENLLTTLLLKEEFINVNKIANDFECSERTIRNDCKY
                     IDEWLSTFCNAYIKRKPNIGIKFSGDGTDKILVNQKLRGEVKRVNSELHKQVEILNLL
                     LCNNKKVTLNDLSNKLYINKNIVREEISKLSVALNNYNLNVSTKKGSGIYIEGDEKDI
                     RIMLVSFLFKYIDKYRLNIDEIEYFHIVDIIIVKNIMLTIEEDMDIRLTDISFKQLML
                     FLLINIIRIRLGNSLKVSNTKKELKLKMLILDIEDELKSNLSIVLNYEEKLFIESLIL
                     GMNKQINSNNIKKSLYLNEELASYTKKIINLVSEESGINFNNDILLYEQLICHLNVTM
                     HQMKSNVYLENPLLDNIKTKFCFLFTVISSSIEIELKGKQITEDEIGYLTLHFQTSLE
                     RKYSKRESNKKASIVCPFSFGVSMLLKVKIEKRFDNIKIIETLREEDLKRDNFNKTID
                     FIIAFQEYENIQKPIFITTPLFTDEDENKLKEFTNKIKEKDTSYKLMNRLMMSDYLIR
                     ELEHDDIYEAITYLTNLLIEKHYAEKEYLQSIITREKSYPTNVGKGILFPHGDMKYIK
                     QSVLCFARLKTPIKIRNGKDIKIILLLAYKKDDDRKVFRELFKEISNLTEDENMLDIL
                     SKCDIEKVKDILI"
     gene            complement(28067..28849)
                     /locus_tag="PC466_000876"
     CDS             complement(28067..28849)
                     /locus_tag="PC466_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HDF2768298.1"
                     /translation="MKICNDNFIKNFKNMINKCLDFIYPENISCIICDKSIKKTNTYS
                     ICKSCFKEMNFIQDGCMKCGKPIIRHSIEKEFIEECSYCFNKDFYFDKSISCIEYNDV
                     TKKMVLGLKYNQKTFMAKYIAQIMKEKLYLENIKFDYILFVPLHKKRLNKRGFNQAQK
                     IAFNLSKIVNIPLLDCISRKKYTRMLYKLNKKERKEELKNVFVVKENVKLINNKNILL
                     IDDIFTTGLTTNEISKLLKLSGANKVFVLTLLTKANDNYIME"
     gene            complement(28852..31071)
                     /locus_tag="PC466_000877"
     CDS             complement(28852..31071)
                     /locus_tag="PC466_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HDF2768299.1"
                     /translation="MEKLEGMISEIVFKNEDNGYTIAHLVNENDEIVVVGCMPTLAIG
                     ESIEVEGKWVNHKIYGTQFEVNSFMPVTPSSLEGIYVYLSSGMIHGIGEKMAKRIIDK
                     FGVDTLEVIQNSPEKLQEVEGIGSKKVKQIVKSYEEDRELRNIIIQLSPFGITPNYCL
                     KIYKKYKSSAIEVINKNPYQLAEDIRGIGFKVADSIASKIGIDKNSKDRICQGILYTL
                     NKSLSNGHTYLPEHVLIQDSEKLLELNGEIIKECVMMLVYNQKIHIEKVNNENLIYLM
                     PYYLAENGVCSQIVKLSQYEFEDLKIDIDNEINVLEEDKKIKLAEKQILAVKESVNSG
                     VLIITGGPGTGKTTTINAIIDIFENNGKSVTLAAPTGRAAKRMSETSNKEAKTIHRLL
                     EMGFSTDDDLTFFKDEEDPINSDVIIVDEVSMVDIILMYNLLRAIKLGTRVILVGDSD
                     QLPSVGAGNVLKDMINSNIINVVKLNEIFRQAQESMIIVNAHKINNGEPLYLNTKGKD
                     FFFIRKSTNEEILNEIIGLVNERLPKFYKVDKLKDIQVLSSMRKGELGVTNLNIELQK
                     YLNKKEKFKVEESFSKRLFRVGDKVMQVKNNYTKKWETEDQKESGEGIYNGDIGYVYH
                     IDKDKKTIYILFDQTKIVSYLYDELDEIDHSFCTTIHKSQGSEFPVVVLPIAWAPPML
                     LSRNLLYTAVTRAKKLVVLVGDVKYLEYMIKNNRVNQRYSNLGYKLNKFKQEGLLIE"
     gene            complement(31335..32432)
                     /locus_tag="PC466_000878"
     CDS             complement(31335..32432)
                     /locus_tag="PC466_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768300.1"
                     /translation="MSGKVNIKTVISFAGAYVATVIGSGFATGQEILQFFTFYGYAGI
                     IGGIISMVLFSWFGAEVIDKGRELKLKEPIKIYQVYCGKYLGTFFEWFGPLFLFGTLV
                     IMIAGAGATLSEYYGLNPYVGRIGMAIVSLITVSLGLTRLSKILGNIGPIIIIFTLLV
                     GAISLFSNIDALSNAGNMVDSLNIKTATSNGYFSGVLYTCYNVIIVITFLTGMGASAV
                     NKKDAVWGGIVGGVALMAAAIMMNLALLSNIGNIYTKEIPALYLADKISPIIGILFSV
                     VLLLGIYTTAVPLLWSVTNRFVEDDHPKFKIITIVVSILACIGGLLPFDKLVGTLYPY
                     TGYMGILILLCMLYRRITKTEGYKENKSEIS"
     gene            complement(32748..33941)
                     /locus_tag="PC466_000879"
     CDS             complement(32748..33941)
                     /locus_tag="PC466_000879"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HDF2768301.1"
                     /translation="MARHLFTSESVTEGHPDKICDQISDSILDALLEKDPQSRVACET
                     TVTTGLVLVAGEISTSAYVDIPKLVRETVREIGYTRAKYGFDCDTCAVITSIDEQSGD
                     IAMGVDEGLESKTGEEIEEEIEKVGAGDQGIMFGFACNETPELMPLPISLAHKLSRRL
                     TEVRKTGLVDYLRPDGKTQVTVEYEGSKAVRVHTVLISAQHCETVSNDKIREDLINHV
                     IKEVIPAELLDEETKIYINPTGRFVIGGPQGDTGLTGRKIIIDTYGGYSRHGGGAFSG
                     KDPTKVDRSAAYAARYVAKNIVAAGLADKCEIELAYAIGIARPLSIFIDTFGTGKVSE
                     EKLVELVNKHFDLRPGAIIRDLDLRKPLYKKVAAYGHFGRTDIDLPWERTDKVEQLRK
                     DALGE"
     regulatory      complement(34078..34181)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            34370..34879
                     /gene="yyaC"
                     /locus_tag="PC466_000880"
     CDS             34370..34879
                     /gene="yyaC"
                     /locus_tag="PC466_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore protease YyaC"
                     /protein_id="HDF2768302.1"
                     /translation="MYLAKVNYSDDDVIQMLSSVLKTIINENTIVVCIGTDRAIGDTL
                     GPLVGTILKNSNFKYPVYGTLDNPIHALNIYESLDTIKNTHIQGNFLAIDACLGSQSN
                     IGNIQIREGPILPGKGVGKKLPQIGNYSIVGIVDKIDENNKLSFNNIRLSFILDLAET
                     IALALLVST"
     gene            complement(34990..35418)
                     /gene="fabZ"
                     /locus_tag="PC466_000881"
     CDS             complement(34990..35418)
                     /gene="fabZ"
                     /locus_tag="PC466_000881"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HDF2768303.1"
                     /translation="MLNIDEIKKLIPHRYPFLLVDKITELEVGKRAVGIKNVTVNEPF
                     FQGHFPEYPLMPGVLIVEALAQVCGVAMMSVEENKGKLGVFAGIDKVRIKREVRPGDT
                     LTMEIEMTTLRKNIAKADAKAYVGEELVCKGELMFALVEK"
     gene            complement(35434..36453)
                     /locus_tag="PC466_000882"
     CDS             complement(35434..36453)
                     /locus_tag="PC466_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein"
                     /protein_id="HDF2768304.1"
                     /translation="MAGADIGIDLGTANVLVYVSGKGIVLEEPSVVAIDKRTDSVLAV
                     GEEAKKMIGRTPGNIVAIRPLRDGVISDYDVTEKMLKSFIDKIVDKKGFGRFFMPRIM
                     VCVPTGVTEVEKRAVEDATRQAGAREVYIIEEPIAAAIGAGVDISQPNGNMIIDIGGG
                     TVDIAVISLGGAVVSESIKVGGDRFDDAIVKYMKKQHNLLIGERTAEKIKFEIGSAFK
                     REEEKYMKITGRNLITGLPSSITINSTEMLEALRECVEQIVVATHAVLEKTPPELAAD
                     IGDVGIIMTGGGSLLYGLDKIIEQRTGITVTIADEPLSCVAKGTGIALGSIDLLETGG
                     SFKRK"
     gene            complement(36650..36910)
                     /gene="spoIIID"
                     /locus_tag="PC466_000883"
     CDS             complement(36650..36910)
                     /gene="spoIIID"
                     /locus_tag="PC466_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation transcriptional regulator SpoIIID"
                     /protein_id="HDF2768305.1"
                     /translation="MRSHIEERAIVVAKYILEKNTTVRQTAKTFGVSKSTIHKDVTER
                     LKEINPSLAKEVKNVLDKNKSERHIRGGLATKLKYEKEHKKM"
     gene            complement(37008..37676)
                     /locus_tag="PC466_000884"
     CDS             complement(37008..37676)
                     /locus_tag="PC466_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M23 family metallopeptidase"
                     /protein_id="HDF2768306.1"
                     /translation="MKKKLLEKDGFYLSLFVCVCLLAVGGVWFTNNNVDKLASNKGIM
                     ENANKDSEEEIHLIEKDKKDAIPTATDSKQNLEKAKSKEENKSSTTKLNYIGDKVIRG
                     YSEKEPSYSKTLDVWETHKGVDISCTKGKEVKSLLNGIVVDVFNDEEYGQSVKIKSDN
                     NIVVVYSNLDKNVSVKKEQKVTEGQSLGTVGSTSQIESEEGIHVHLEAYSGEKSIDPM
                     SLIK"
     gene            complement(37742..38806)
                     /gene="spoIID"
                     /locus_tag="PC466_000885"
     CDS             complement(37742..38806)
                     /gene="spoIID"
                     /locus_tag="PC466_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein D"
                     /protein_id="HDF2768307.1"
                     /translation="MKNPLVVLLGFVTCSVLVPSLITLVSYKNVELTEKPESPVSINK
                     TIKKSDIEDKGNKEEKSTVSYETVNKKAPIINVYNHITGKTEKMDMENYLCGVLAGEM
                     SSEFDIEALKAQSVAARTYVVYKQEHGKSSKHKNAVVCTDYKHCQEYKSYDTLKKLNG
                     EEWIKNKYSKIQEAVRGTKGQIITYNDKAILPLYFSTSSGKTENSEEVFSAKYPYLKS
                     VESPYDKYSPKFASTLKISNTDFVKSLRRAYSTIVIDVNNLSKQVSITKRSDAGTVEK
                     IKLGNKELTGKDIRTVFKLNSANFDIKFGEGYIDFVVKGYGHGVGMSQWGAEGMAEEG
                     YKYYDILSHYYTDTKIKDIY"
     gene            complement(38893..40146)
                     /gene="murA"
                     /locus_tag="PC466_000886"
     CDS             complement(38893..40146)
                     /gene="murA"
                     /locus_tag="PC466_000886"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HDF2768308.1"
                     /translation="MAKIIVKKSNPLKGSVKIDGAKNAVLPIIAATLLANGKSTLNGV
                     PNLRDVHVISDLLRHVGAEVEYKENTLTVDASNIKTCEAPYELVRKMRASFLVMGPLL
                     ARFNSTKISMPGGCAIGTRPIDLHLKGFKALGAKIEMDHGFVEAATEKLVGNKLYLDF
                     PSVGATENIMMAASLAEGTTIIENAAEEPEIVDLANFLNEMGADVKGAGTNTIKIKGV
                     KELKGAEHNVIPDRIEAATYMVAAAMTKGDITVENVLMEHLKPVVAKLREAGCEITEM
                     DNSVRVVGPKVLKPIDIKTLPHPGFPTDVQAQFMAMLTVANGTGVVIETVFENRFMHV
                     AEFNRMGANIKIDGRSAVVNGVDELHGAAVNATDLRAGAALILCGLIAEGETQIGEIY
                     HIQRGYVDIDKKITALGGQIEIVED"
     gene            complement(40167..40904)
                     /locus_tag="PC466_000887"
     CDS             complement(40167..40904)
                     /locus_tag="PC466_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YwmB family TATA-box binding protein"
                     /protein_id="HDF2768309.1"
                     /translation="MKKVKLAISFFILMIIGMTISYADTSINTRYNRLSKALEISEAN
                     FKFYNVKINSVINHNLSNKEFHNIFIEIINNLKLDKKGINWNQKGSGDKIQLCATIKG
                     SDKEISIKGINKNNKESYIVVDILDNKVYKHKEVIYSNVENVLNKYSSQVDVSACIVG
                     EYTKRLQNNKYDDILQKILYNMSAKQIDEVKDVNFLSITAYSKVLNDYELEYLGEKIN
                     LNIGIKYNEDDGKTLIYIATPIIKLDY"
     gene            complement(41388..42683)
                     /locus_tag="PC466_000888"
     CDS             complement(41388..42683)
                     /locus_tag="PC466_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate sulfurtransferase"
                     /protein_id="HDF2768310.1"
                     /translation="MTNDFKKEKKEDYFVNLKAISTEVLQEKMQDNAWVIVDTRLNDA
                     YNGWKLDGVKRGGHIKRAVDFSANWLNVYSDRKDEVLEQALKTKRIDLDKNIVLYDAN
                     GKDALVVADYLSKKGYKYLYKYDIKQWADDENLPMERYKNYQMIVPAFIIKDILDGKI
                     PETFEDSKNIKMIEASWGEESYTKGHIPTSVHVNTDIIEPPPTWMLDNDDNLTKFALD
                     YGLTKDDTVIVSSITPMASYRLAVILRYIGVKDVRVLNGGTNSWLSAGYELEFISNPK
                     HSCTNFGADIPVNSQLVVTTSELRQKLKEKNKFILVDNRTWDEHIGKVSGYTYYDKKG
                     RIPGALYGHSGSNSVSLEEYRNIDNTMRNKSEILEMWDKENIDVNKQLIFMCGSGWRA
                     AEVLTYANVIGVENTSLYSDGWMGWSLDNSNLIEVGEHK"
     gene            complement(43136..44968)
                     /gene="glmS"
                     /locus_tag="PC466_000889"
     CDS             complement(43136..44968)
                     /gene="glmS"
                     /locus_tag="PC466_000889"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003401499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HDF2768311.1"
                     /translation="MCGIVGYLGSRKAAEVIVEGLSKLEYRGYDSAGVAVNSSNEEEL
                     NIRKFKGRLSVLAEDLEKNPIDGNLGIGHTRWATHGEPSDVNSHPHFNQAKTIAVVHN
                     GIIENYMEIKEELISEGVKFESQTDTEVIAHLVDKYYEGNLLDAVYKTISKLRGAYAL
                     GVICKEHGNELVAVRKDSPLVVGVGEGENFIASDIPALLKYTRDVYFLENGEVVHLKD
                     ENVTVYDSNRNLVEKEVFHVTWDVEAASKGGYDYFMSKEIHEQPTGVRETLERRLDDN
                     GNIILDSINISKEDLEKINKVYIVACGTAYNAGLLGKYAIEKFVNIPVITDIASEFRY
                     SDPFVDENSLVILVSQSGETADTLAVLRDSKAKGARILSITNVVGSSIARESDDVFYT
                     WAGPEVAVASTKAYTTQITSLYMIALDFAIKKGTITREFYDSMISKMKEIPSKIQEIL
                     DNEEYIKEVAKTVVSSEHAFYLGRGIDYSLAMEGSLKLKEISYIHAEAFAAGELKHGT
                     IALIEKGTPVIAIATQEKLFEKMVSNMEEVRARGAYVVAIAQSHNKDVEKAADKIIYI
                     PNSDDILSPILAVVPMQLLAYHVSVLRGCDVDKPRNLAKSVTVE"
     gene            complement(45235..46581)
                     /locus_tag="PC466_000890"
     CDS             complement(45235..46581)
                     /locus_tag="PC466_000890"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HDF2768312.1"
                     /translation="MRKYFGTDGVRGVANTELTCDLAYKLGRAGGFVLAQGDHRVKVV
                     VGKDTRISGDMLEASLIAGLMSVGCDVITVGIIPTPAVAYLTRKYGADCGVVISASHN
                     PVEYNGIKFFNKNGYKLDDEIELKIEEYIDDIDKIDCLPIGENVGRKLHEHCAQRDYV
                     DYLKSIISTDFKGLKVVLDCANGASYKVAPIVFDELGASVISINSSPDGNNINYKCGS
                     THPEQLQRAVLEHNADLGLAYDGDADRLIAVNEKGQIVDGDHIMILSALNLKKNNKLA
                     QDTLVVTVMSNIGLTIAAKENGINLSTTAVGDRYVLEDMVKNGYNLGGEQSGHMIFLD
                     YNTTGDGVLSSLILANIILQEKKPLSEIASIMSQYPQVLVNATIKNENKNKYMEYPEI
                     KTEIERIESILNGNGRVLIRPSGTEPLVRVMLEGKEEGQIKELATNLANLIQEKLS"
     gene            complement(46751..47308)
                     /locus_tag="PC466_000891"
     CDS             complement(46751..47308)
                     /locus_tag="PC466_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase family
                     protein"
                     /protein_id="HDF2768313.1"
                     /translation="MSTARVICAGFGGQGVMSMGQLLTYAGMLEGKEVSWLPSYGPEM
                     RGGTANCAVTVSNEPVGSPLITDDATAAILLNIPAFEKFKDDVIPGGKIIVNSSLIKE
                     KVDRTDVDVYYIPANELAAELGNDKVANMIMLGAYLKVSDTVDIESVLEAFKKVFGPR
                     KEKFVPLNREALQKGMDATCSKATN"
     gene            complement(47309..48061)
                     /locus_tag="PC466_000892"
     CDS             complement(47309..48061)
                     /locus_tag="PC466_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate oxidoreductase"
                     /protein_id="HDF2768314.1"
                     /translation="MAVVFKKTEGLQDTQTHYCPGCTHGIIHRLVGEVLEELGVLGDA
                     VGVVPVGCSVLGYKYFNCDTQEAAHGRAPAAATGIKRVHPENTVFTYQGDGDLASIGT
                     AEIVHAAARGEKITTIFVNNTTYGMTGGQMAPTTLVGQRATTAQSGRNAETQGYPIRV
                     SEMLATLTGAVFVERVAVDTPAHVRQAKKAIKKAFQVQQAGLGFGIVEVLSTCPTNWG
                     LAPNDALQWLRDNMIPYYPLGNFKNVEVEEVK"
     gene            complement(48061..49140)
                     /locus_tag="PC466_000893"
     CDS             complement(48061..49140)
                     /locus_tag="PC466_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate dehydrogenase subunit
                     VorB"
                     /protein_id="HDF2768315.1"
                     /translation="MAKILMKGNEAFGKAAIEAGCKYFFGYPITPQSELPEYLSRELP
                     KIGGAFVQAESEVSAINMVYGGAGAGARVMTSSSSPGVALKQEGITYAVGAEVPCVVL
                     NVMRGGPGLGSIQPSQADYFMSTRGGGNGDYRTPVFAPATVQEAVDMIMEAFDVADYY
                     RSPVMVVADGMIGQMMEPVEFRAPEKKRELPPKDWATVGTKGKRKPNVINSLYLEPEV
                     LEDHCWHLQEKFDAMEKNEVQYEMYKTEDAEFVFAAYGTTSRVVKSAIDILREEGIKA
                     GLIRPKVLWPFPFEAFNQIPNARNILTVEMSMGQMVEDVKMAVEGKLPVYFHGRPGGM
                     TPTPAEIVEKAKKIIAGELVAGGAR"
     gene            complement(49169..49384)
                     /locus_tag="PC466_000894"
     CDS             complement(49169..49384)
                     /locus_tag="PC466_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDF2768316.1"
                     /translation="MAKGKVSFNQERCKGCGLCVEACPVKIIQLDSNVINKKGYNPAT
                     VFEMEKCIGCASCATMCPDVVITVERD"
     gene            complement(49427..50104)
                     /locus_tag="PC466_000895"
     CDS             complement(49427..50104)
                     /locus_tag="PC466_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF2768317.1"
                     /translation="MITNDKRIRIITGHYGSGKSEFAMNYVVKLRDMVSGKVAIADLD
                     VVNVYFRTREKKELMKSLGIQPIDSSINAPTLDLPAVSAEVMSPMVDHSYNSVIDLGG
                     DNVGARVIGRFSHLLKEGDYDMLFVINANREKTQTSEEVIQYIKEIEKSSKLKVTGLI
                     NNTHLIRFTTIDDVLRGQKVAKEVSEKCNIPIRYVACLENLVEQLPKDLEGEIFPIKL
                     YMREDWM"
     gene            complement(50094..51173)
                     /gene="buk"
                     /locus_tag="PC466_000896"
     CDS             complement(50094..51173)
                     /gene="buk"
                     /locus_tag="PC466_000896"
                     /EC_number="2.7.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="butyrate kinase"
                     /protein_id="HDF2768318.1"
                     /translation="MSKIFKILTINPGSTSTKIAVFDNEDLVFEKTLRHSSEEIGKYE
                     KVSDQFEFRKQVIEEALKEGGVKTSELDAVVGRGGLLKPIKGGTYSVSAAMIEDLKVG
                     VLGEHASNLGGIIAKQIGEEVNVPSYIVDPVVVDELEDVARISGMPEISRASVVHALN
                     QKAIARRYAREINKKYEDINLIVAHMGGGVSVGAHKNGKIVDVANALDGEGPFSPERS
                     GGLPVGALVKMCFSGKYTQDEIKKKIKGNGGLVAYLNTNDAREVEERIEAGDEKAKLV
                     YEAMAYQISKEIGASAAVLKGDVKAILLTGGIAYSKMFTEMIADRVKFIADVKVYPGE
                     DEMIALAQGGLRVLTGEEEAQVYDN"
     gene            complement(51195..52097)
                     /gene="ptb"
                     /locus_tag="PC466_000897"
     CDS             complement(51195..52097)
                     /gene="ptb"
                     /locus_tag="PC466_000897"
                     /EC_number="2.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate butyryltransferase"
                     /protein_id="HDF2768319.1"
                     /translation="MRSFEEVIKFAKERGPKTISVACCQDKEVLMAVEMARKEKIANA
                     ILVGDIEKTKEIAKSIDMDIENYELIDIKDLAEASLKSVELVSQGKADMVMKGLVDTS
                     IILKAVLNKEVGLRTGNVLSHVAVFDVEGYDRLFFVTDAAMNLAPDTNTKKQIIENAC
                     TVAHSLDISEPKVAAICAKEKVNPKMKDTVEAKELEEMYERGEIKGCMVGGPFAIDNA
                     VSLEAAKHKGINHPVAGRADILLAPDIEGGNILYKALVFFSKSKNAGVIVGAKAPIIL
                     TSRADSEETKLNSIALGVLMAAKA"
     gene            complement(52401..53582)
                     /locus_tag="PC466_000898"
     CDS             complement(52401..53582)
                     /locus_tag="PC466_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768320.1"
                     /translation="MINRLKNNTKIKIISFLSAIALWMYVMAVVDPEETKGFEDIPVS
                     ISNMSDLKDKNLVIYPDEKLTADVYIKGSLSKVQSVKKEDIHVYGTIEDPIQGQKEVY
                     LKANIPQGVTLEFKHDVLVVNLEKNIKEKRDIKVEVSGNSKRNINKIELSKEFVDVSG
                     PRTLVKEVKSVRANLDVGNETDDFSKKLQLIPLNSDGTKVEGVTLSSSFVTAKIELLK
                     EKIVPIRVSLNDNKDNDVLKNYKLSKEQVTIKGKKEDIDKISYIKTKPIDLADLANGE
                     EKEVSLEIPEGITLEDSSITIKLNDTKQLSAEFLYNAGDIELRNIPTNIDNPNVISDV
                     DIKVVVESTEDLSKLNKKDISLYIDLSQGPEEDSKYKIKYETTYQFKKINIEPNIVEV
                     E"
     gene            complement(53579..54418)
                     /locus_tag="PC466_000899"
     CDS             complement(53579..54418)
                     /locus_tag="PC466_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HDF2768321.1"
                     /translation="MLDINSFLNGFFNIILRMSIYDLIDISIVAYIFYKIFMFIKDTR
                     AEQVFKGIIFLLLATQLSNTFKLHTVYWISLKALDYGVIAALIIFQPEFRAGLEHIGR
                     AKFNLFGKNVNTSEETLNRNIEEIVEALYSLSRQKIGALIIMERETRISDIINTGTII
                     DAEISRQLLINIFIPNTPLHDGAVVIRDSKVKAAACFLPLTESKDLSKDLGTRHRAGI
                     GVSEVSDCITLIVSEETGGVSIAKAGKLYRDISRERMMNILRSNLKTNTETRSFFKGG
                     IFK"
     gene            complement(55394..55467)
                     /locus_tag="PC466_000900"
     tRNA            complement(55394..55467)
                     /locus_tag="PC466_000900"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(55431..55433),aa:Arg,seq:tct)
     gene            complement(55477..55551)
                     /locus_tag="PC466_000901"
     tRNA            complement(55477..55551)
                     /locus_tag="PC466_000901"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(55517..55519),aa:Gly,seq:gcc)
     gene            complement(55562..55638)
                     /locus_tag="PC466_000902"
     tRNA            complement(55562..55638)
                     /locus_tag="PC466_000902"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(55602..55604),aa:Asp,seq:gtc)
     gene            complement(55644..55719)
                     /locus_tag="PC466_000903"
     tRNA            complement(55644..55719)
                     /locus_tag="PC466_000903"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(55684..55686),aa:Val,seq:tac)
     gene            complement(55725..55798)
                     /locus_tag="PC466_000904"
     tRNA            complement(55725..55798)
                     /locus_tag="PC466_000904"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(55764..55766),aa:Gly,seq:tcc)
     gene            complement(55813..55887)
                     /locus_tag="PC466_000905"
     tRNA            complement(55813..55887)
                     /locus_tag="PC466_000905"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(55852..55854),aa:Glu,seq:ttc)
     gene            complement(55895..55970)
                     /locus_tag="PC466_000906"
     tRNA            complement(55895..55970)
                     /locus_tag="PC466_000906"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(55935..55937),aa:Met,seq:cat)
     gene            complement(55986..56071)
                     /locus_tag="PC466_000907"
     tRNA            complement(55986..56071)
                     /locus_tag="PC466_000907"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(56035..56037),aa:Leu,seq:taa)
     gene            complement(56077..56151)
                     /locus_tag="PC466_000908"
     tRNA            complement(56077..56151)
                     /locus_tag="PC466_000908"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(56117..56119),aa:Asn,seq:gtt)
     gene            complement(56159..56275)
                     /gene="rrf"
                     /locus_tag="PC466_000909"
     rRNA            complement(56159..56275)
                     /gene="rrf"
                     /locus_tag="PC466_000909"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT        17016 a        10675 c         6088 g        22573 t
ORIGIN      
        1 ggagtattaa attaatgaac ttaaaattaa tatggataaa tattctaaac ccagtattta
       61 ttaaaaatga aataaaaaga aaaaaaatac aaattattat ctttttcttt ataaactttg
      121 gtttaactta ttcattaggt ttactgttat attataataa atttattgat ccagaaaact
      181 ttgcatcatt catgatgata ttacctctat cttcagttgc tattgcaaag ttttatactg
      241 aaggattaaa taatgatatg tatgaatttt attcactaat catattattt tttcttattt
      301 attcattatt aattgttctt aagttattaa atctaataaa taataatgaa tttataatta
      361 taaacctaat attaactttt ataagtagct tatcaattat aatatattca tcaaataaaa
      421 aaaatttata tcctgtaaaa aatattaaac taggttcttt attaattatt tactttatga
      481 tttctgtaat tgttccaaca tcatttatac taatactaca aggggctcaa cctaattata
      541 gtggtatcat aaaatttata tttactccaa taacatcatt aactactatt tatatttttt
      601 ttagtgaaga atatgcctgg agaggttttt tacagaatat tttttttgat aaatttggta
      661 aaaaattagg agtcataata ttaggtatgt gttggagctt gtggcactta ccactaatat
      721 ttacattata tacacctgaa gcgccaatat taggagtaat attacgttca atacatatag
      781 ttggaatttc aatattttta ggatatcttt atataaaaac taagaatatc tggttttgtg
      841 ctataattca tgttttaaat aatagtgctt ttcttatcac aaattctaaa gaatcaacta
      901 tcacttacca tgatatacta atagtatcta tggttgtttt aattttttat gttccatttc
      961 tatttacaaa agaatataaa aataacttgg agtaaataga atatccaagt tatttttata
     1021 tttttgtaaa tttccaacaa tcctacagaa tactttaagt ttagaagata ttattaaaat
     1081 ttattataat caactaattc ttgatattag tcacatttac tttatcacta acaaaatcat
     1141 acttagaatc tctatagtaa taccatacaa atataaagct aagtagatta acaaaagtag
     1201 tcaaaattcc accttcaata ccaaacatcc ctccatttaa tagattacca tgagtgattt
     1261 gtgtagttat aatccctgga acctgaagtc cacttacagg cataccatat ataatcccct
     1321 gaaatacatt ccatgtaaaa tgataaccta tacacatcca tatattcgac gactttataa
     1381 acatatatga aaaaagaatc ccaataatta taatattaat tacagacaaa aaagtaacat
     1441 caggattcca tatatgaatc aacccaaaaa taacagatgg aacaatcatt ataaaataaa
     1501 tatttttaca tcttcgtaaa actgccataa aaaaaccacg atttaaaatt tcttctgcaa
     1561 aagcaactaa aataaagaca agtatccaag aaactgttaa aggtgaaatt tttggtaccc
     1621 atgaagtaac atgaccacca ccaattgtta ttgttataat aaagattact gtacaattaa
     1681 atattcctaa taacattcct acatatcctt cttttttctt aattctataa gaatgtaatc
     1741 ccatttcact aataggattt ttcataataa atctccatac aattatagga ataataatca
     1801 taagtgaatc tgttagaatt tgaaatacaa cctgtaaccc aacgtcattt aaccaattag
     1861 catattccga aaaatagttt gtttttaaat taatgtcacc tgtagcaatc agaatttttc
     1921 ttattatttc cataagtata gtgcttaaat aatactcaaa tatgtaaaag gcagccataa
     1981 cagttataat aatccaccct gaacgtactt ttttgtcttt attcttaata atcaagttac
     2041 tccatgattt gttcatatag atgtcttcct cctaactatt atttttagtt gtttctaaaa
     2101 tatattctat taaatttctt catagtagta ttttaccaca aaacttctgc ttcaataaag
     2161 taaacgtaat atattctcta actgtaattt aaactataaa aaatatataa agtataaatt
     2221 taaagtaata tttatggaca taaagcaata tgaacaatat ataaaacata taaaacttta
     2281 cttaattatt tctacataaa aaccacataa aaaaggatgt aactctagct tttagtgtaa
     2341 catccttttt taattaaaaa aacttgtatt tgattttaaa aagctgtctc atgaccaaca
     2401 tagcaagcta taccattatc caaaaatata tcttgtaatt cttcaagatg ctcttcatca
     2461 atatctccct tatcagaata ctcatactcc ttacctaatt gaatccactt tgattctcct
     2521 agcctatgaa atggtaataa gttaatctct attaaattat ttttgtgcat aaaagatata
     2581 atatcactta tattttcagc actatcatta aacccagaga taactggtac tctaagtact
     2641 aaccttccat tccagtcaga atttgcaagg tttgatatat tttctaatat taaatcatta
     2701 tatacacctg tttgttcttt gtgtttttct ctatccatat gctttatatc aataaatgca
     2761 aaatcaatat ctttaaatat tttattaaaa acttcatttg atacacatgc acttgtttca
     2821 atggcagtgt gtatatttac ctcatgacac tttaataata cttcatgtaa aaattcatgc
     2881 tgaagtagtg gctcacctcc actaaatgtt actcctccat tacttctcca attgttagaa
     2941 tcacgtttaa ttacctgcac aagttcatct acagtataag gttttgcaca taatttaaac
     3001 gcattataat aacatgagtt gacgcattca aaactttcac agtccttaca gatgttccaa
     3061 tctataactg gcttattatc aagattaaag ctcaatgcac catttttaca cttaccatga
     3121 catacagtac atccattttc atattgacaa gataattcac taaacatcat atgtggtctt
     3181 acagtccaac tttctggatt tgcacaccat ttacaactca gtggacatcc atttaaaaat
     3241 acagttgttc tacaacctgg accatcatga actgaaaagc tttgtacatc gaaaatcatg
     3301 ccttctaatt gcttttgact actcattaaa cacatgtcct tcacaagtaa ttgcattcaa
     3361 tgttgaatat acccagtctt ctttctctag gccaacacat ttgcctatac cttcatcatt
     3421 agcttcaaca aaatttttac aatttttaca ttttggcatt acttttatct ctggacatgc
     3481 tgaatcatct aaattaatca tttgttttga taatctacaa attcctttgg ttgcatctac
     3541 tgcacaaaaa ttcatacaat cactatgctt tctcatattt tacacccctt catactctgt
     3601 tctagcaatt acttcatctt gtattggttt acctaattca caccaatatt gagtaaaccc
     3661 agcaacacgt accattaatt gacgataatt gtcaggattt ttttgtgcat cttttaatgt
     3721 ttctgaatct acaacattat attgaatatg gaacccacct tttcttaaat aacttcttgt
     3781 taaatctaat aattttttag ttccttgttg tccttttata gtagttggat gaagttttaa
     3841 attcatctga gaattttgaa ctactgcttg gtcccaaata gttgcagatt caaataatgc
     3901 atatactcca tttttatctg ttcctgcata tgcagagact gaaccatctg aatatgttgt
     3961 tccacttagt ctaccatctg gagtagccaa ggtagcagct ccctgtggtc catgtgtaga
     4021 aacagatatt tggcaagggt acatcttctt agcatataaa gattgtgctt cttcacatac
     4081 ttttgataac catacctcat agtttttaag aatattatct gcatacaaat cattatttcc
     4141 atatttaggt gcatcaagac aggccttgta aatagcatca tatttaccag tcttatctac
     4201 ttttacttgg tctgccatag aataatttcc tacttctaat gcatctttaa atccaaaatt
     4261 atttaatatt gcatccttca tttcctctat tgtaaatgct ttgtcatcat atacaagttt
     4321 cttaagtgct gcaaatgaat tgaccatagt aacagtacca caagtttcta cgtttaatgt
     4381 tgcattataa cgatatccca tatttcctat atgttgacct ttgtctaaac agtctggctt
     4441 tagtagtgaa tttattatag aagtatcaaa ttttctccat atatctaact caatgttatt
     4501 tgctctttct aaaacattta ttgcttgttt ataataatct ttaaatactt ctatgacttc
     4561 ttcataagta tctaatggct tattatgagg ctcaaatact tgtatattca tacgatggtc
     4621 tttaccattc ataagaacaa gttctaaaat tttgggatta gctataaagt gaactccaga
     4681 gccagcagat tgacctgctc cacctgcaat agagtacgtt tttccgttta aagttaactg
     4741 tttccaacac cctggagacg tttccaaaca tccacctaat gcaaatgctc ttgcttcttc
     4801 aacagtcata ccttcatcag caaattgttt catcataaat gttgttccat ttgagttgtt
     4861 tacccaggct ggataaccag aaccaagctt tgtacattca gcagctttca ttaagaaatc
     4921 ttctggaagc ttttcatcat atagcatagt taaactaggt tgaggagttc tacatctcat
     4981 acttgcttct aataataact cttctagttc attagctcct gtagaaccat cttcttttaa
     5041 tccacctata gataaagtat taaatgtatt acctgatagt actcctccat ttacgcccgc
     5101 tgaagcaaaa cagtcaatac aagtgatttt tattctataa agctctaata attcgataac
     5161 ctcttctttt gtaattagtc ctttttctat atcttgttca taccaaggat ataaaatttg
     5221 accaaaacgt cctatagaca taccagatat agcatcctca tttactgatg ctatatgaat
     5281 tgtataagtc aactgaagag cttccctaaa tgtacgaggt tgtttatgtg caatatgttc
     5341 taatatctcc actaaatctg agtattcttt tttagcttct aaatctgtct ctatactttc
     5401 taaatatttt gcatgttttg cataatttaa aatccaagtt tgtaatcctt caataacttg
     5461 aataacagcc tcataaaaat atagacggtc cataccaata agcccatctc cagatgcatt
     5521 tcctgcaact gcctttttac attcttttgc catttctata attccatcta atccataatt
     5581 taaaggataa aaataattta taacttctct accttgagga agtgtatacc ctgaatcaaa
     5641 catgcatata agtgtactca ttaggttttc ttttaaatca taatctggca tcattttttc
     5701 atagtgaaaa cctaaatctt caacagactt tccaacccat tcctttgcca tttttacaag
     5761 tacaggtact tcttcttttc tcattccgaa tttaccagct attgaaacga catttccaaa
     5821 actttcagta acatttcctc caccagaccc aaattttgta agttcatcag ctgtgttact
     5881 ggctaatttc tttgcctctt ctctcatttg ttctccttga gcaacaaaga aactttcact
     5941 tacccatggc attggaaaag aacctctata atggcgtgtc ttttgcatta ctattttctc
     6001 accaggtatt atatttggtg tcatatgtga aaaagcagct ttaagagctt tagctcttct
     6061 aactactggt atatcaccat ctgattttct atattctcta ttataccaat atggaaattc
     6121 catatcagca gtagataatg tattataata tacatctaat aagtcttctg ctcttttact
     6181 tgcttttttt tcattaaatt cacttaaatt ttctttattt tgaaaatttg atttaatatt
     6241 ttttgcttcc aaaatacttc ttattttgtc ttctttactt tgactcattt cttcccctcc
     6301 ttaatctttc tataattagt ataaaacttt ttaagaatga aaaaaaaggg tatattaccc
     6361 actttttaaa ataatctttc tatagaaaaa attaaacttg aagcaaatct aagccaaaga
     6421 caatctgtat atcctaaaat ttgttgcaat tcattggaat ataaagatta taaatagttt
     6481 tacttcaagt tttaatatat actatattta tttttattat atttaatttc acttctactt
     6541 acttttttga aacaatactt ttatatttac aaattcatct aactctactg atttatcttt
     6601 aaatttggaa ctgcatttaa actcatatca tgcgttttcc catttataaa attataatat
     6661 cctgcacacc ctatcatagc tgcattatct gtgcataaaa ttagaggagg atacttaaca
     6721 gtaataccat tgtctttagc aagctctgtt attttagctc taagccccga attagaagca
     6781 accccaccag aaagagttat gatattgtat cctttgtctt ttactgcttt tagtgcttta
     6841 ttagataaaa cctctactac agcctcttgg aaagatgctg ctacatcttc aactactatt
     6901 tcttcatttt tcattctttt tccatttaga taatttaata cagaagattt taatccacta
     6961 aaactaaaat catagctatc ttcttctaaa taggctcttg gaaattctat agcatgttta
     7021 tttccattct tggccagatt atcaataata ggacctcctg gatagcctaa attcatagct
     7081 cttgaaatct tatcaaatgc ttctccagat gcatcatctc ttgtttttcc taaaatttca
     7141 tacttgccat aatcttttac ttcaaccaag tgagtatgac ctccagatac tattaatgtt
     7201 ataaaaggag gttttaaatc cttatgctct atatagtttg cacttagatg cccttctata
     7261 tgatttactc ctacaagtgg aatattcaaa gtatatgcaa gtgctttagc ataagataga
     7321 ccaaccaata aagcacctac tagcccaggt ccatatgtaa ctgcgatatg gtctatatca
     7381 ttaaaaccta tatttgcttt gtctaaagct tcttgaacaa ctatatcaat attttccaca
     7441 tgttttcttg aggccacttc tggaactaca ccaccaaatt ttttatgtgt ctcgatttga
     7501 gtagagatta tgtttgaaag tacttctcta ccatttttta aaactgatgc agctgtttcg
     7561 tcacaactac tctctatagc taatgttatt atatcactca taaactctac acctctttta
     7621 attggttcca cattataatt gcatcttctt tattatcact gtagtattct tttcttattc
     7681 cacccatttt aaatccatat tttctatata aattttgtgc tattttattt gatgctctaa
     7741 cttctaatgt catagatgca atattattat ctttacataa atcaactatg cattttatca
     7801 acttgtcccc tatttttttc cctctatagt cactatgaac agccacatta tttatatgcc
     7861 cttcatcaag tataagccaa attcccacat atccgacaat ttttccattt aacttagcta
     7921 ctatatacct tgctacttca ttagacaact cttttctaaa agactctttt gaccaataat
     7981 cttcaaaaca atttttttct acttcaaaaa cttcatctat atcttctgta gtcatttctt
     8041 ctatttttat atcatctact attagttttg tattatcttc cattatttag cctcttcatt
     8101 ttttcatcat attgtacttc agcttgagat tttctgatat acataggatt tatcgtataa
     8161 caagtatgta catctatatt tttattatat ttatttaatg ctaaagagca taagcttcct
     8221 gcgttagata cattattagc tggtgaaggt atttttatat tttttatatt ctctaacttg
     8281 tctttatatt tgtatacagc ttctccaact attataaatt cttcattagt tgatacaatt
     8341 tcatctacta aagcatcaaa ctctacaaca tcaacaccat ctaattctat catctctcca
     8401 ttttcaaact tgtatttagc tgaataaact tgatttttct gcgcatctaa tatacaacat
     8461 atctttctat cacagaaatt tatgttattt gctagagatt ccaaagaatt tactgctatt
     8521 attggtatat tatttacatg ggccatagct tttactgtag ccatacctat tctaagtcct
     8581 gtaaacgaac ctggacctat acatacagct aataaatcca tatcttttat acttaaatca
     8641 ctcatactca acatattttc tatcattggc ataagctttt gtgaatgagt ttttttgttg
     8701 tttactgtaa actcacatat taagttatca tcttcaacaa ctgctacact tgctgccata
     8761 gaagacgtat ccatacctag tattttcatt atttaatcaa ctcctcaact atctctttat
     8821 aaaactctcc ttttggagtt aatatcattt ctcttccttc atctttatat ctcaattcta
     8881 tattcaaata ttcttttgga agtatatctt ctattagatt agcccattct attatacaga
     8941 ttccatttga atttacatat tcatcataac caatatcata catttcatca ctactaccta
     9001 ttctataaac atcaaaatga tacaaaggta tttttccttc atattcattt attatagtaa
     9061 aagtaggact tgttatataa tcttctatcc ctaatgaatc tgccaagctt tgtgtcattg
     9121 tagttttacc agctcctaaa tctcctacta aacagataac actgccttct tttaaaagtt
     9181 tacctaattt atatcctatt tctctagttt tattttcatt ttctaaatat atttttgcca
     9241 tcaattcatc tccattttga tataatcgtc atgtgaattt atatcactgc ttaattaatt
     9301 atagtataag cctagattat tataaagtac ttgtctttat ctttttttat ctttcactat
     9361 tgatggctgt atctacacct tatatacaat catcaatagc aatttttaca tactcttttg
     9421 ctttatggtt ttgcttcaat gcttctttac atattctctc agattgctct tttacatact
     9481 taagagactt atagttctct tttactgctt caatacacat tttttctgtt tgatttttta
     9541 tatacataag catttttcca ttttgtctta caatctctat acatatatct tctgtatact
     9601 tatctatgta acttagtaca tctttaatat tatatttttt atttaaatat cttatagcat
     9661 ttatacatat ttcttctgtc ttattgttga caaattgtag acttcttcca tcttgtttga
     9721 cagcttctat acatatttta tcagtttgtt tatttacata ttgtaatgcc ataccatttt
     9781 gtcttacgga ttctatacac attttttccg tttgattttt tacatatttt aatgctttat
     9841 aattttgctt aatggcctct atacataatt cttcactctg ttctctaacg tatgcaagac
     9901 acctgccatc ttttttaatt gcttctaaac atatccttct tgtttgagtc tctaaagcct
     9961 ttagtatact tacaacatct atattggaag aatgacttat tgcttttata ataagccctt
    10021 ctgttttatt tcgtacatac ttaagtgcat tacaatcttt ttttatagct tcaagacaca
    10081 agtattctgt ttgttctttt acatattcaa gtgctttata attatacttt attgcctcta
    10141 aacataattc ttcggtttga ttttttacat actctaatgc cttgtaattc tgccttattg
    10201 ctaaaataca cataccatca gtttgatttt ctatattttt taattcacga taatcgtatt
    10261 ttaccctttc catattttca atatattcat tagtgatata ctttaaagaa tctcctaatt
    10321 ttgtatcata aataccaata tgaatatctt cccaattact attaaaataa taccctttat
    10381 catctaaaaa taattttttt atttttttag ataaatgcat gaatatacac ccctatcatt
    10441 attaaattag ttattattaa aagtttgatt attagtcttt atagtttttt aataataact
    10501 ttattttttg tttattataa attcgctctg tatattgtag ataccttttt catattttaa
    10561 tagttaatcg ttttaattct tcctttattt taaaatttaa atttgtctaa atatttctta
    10621 ttttatatac attttttgat aaattaataa agccataata tatttaatat atcaatcaca
    10681 atataggact gaagttataa ataaattatg gctattcaat acatttaatt ttatattttc
    10741 ttgtctaatt atttctttat tatatttccc atttttttat aaagtggcaa tgttactaaa
    10801 gatattataa cagccttcag cacattaaat ggagctatca tccaaattac aaaagtgaat
    10861 aaatcatgaa cttgaggatt tatagctgaa cctaaaccta ttatagcatc tagtcccata
    10921 agttgaccat aaagtggcaa cattacaaaa taatttacta atgaaccaat tatagtcata
    10981 gatattgttc ctaatacaaa accaatcagt acacctttta aatctccact tctcttatat
    11041 gaataacaaa gtatcattac ataagaacca ccaattaata tatttgcaaa ttctcctatt
    11101 cctccagttg ttgttgctgt tattgcttgt aacacatttt ttactacaac tattccaaat
    11161 ccaactaatg gtcctagaga cattcctccg aatattgctg gaatatctga taagtcaatt
    11221 tttaagaaat ctggaaatat acctggtatt ggtgcttgaa taaacattaa taaataagat
    11281 attgcagata aaattgacat tactactaaa gttcttgttg aaatcatatt gcctcttttt
    11341 gctgtgtttt gcataattat tttcccccta atcaatatgt ttatattttt taggaaaaac
    11401 aaaaaactcg aagaccctat cttcgagttt ttatggatat agtttaaaca aactaaaata
    11461 aacttattta tcttccataa atatcttctc tcatccagac tttactgtcg gctttggaat
    11521 ctcaccaaat caaccaccta agtagttcgc gggctatacc gccggtaggg aatttcaccc
    11581 tgccccgaag atcttctttg attttttaat tttccttaca ctcttatatt agttaatttt
    11641 ttaataattg tcaagttatt ttttctcata cactactttg ccatttatta tagtgtaaag
    11701 tacattactt tgaatctcta gtggagaatt atcccaaatt actaggtctg catctttacc
    11761 aacttctata gagcctactc tatcttctat tcctaaagtc ttagctggat ttatcgtaat
    11821 tgattctatt gctttttctt ctttcatacc atgttttact gcaatacctg cacatattgg
    11881 aagatattga actggtatta ctggatggtc tgtcattata catacatcaa gacctgcatt
    11941 tgaaagtatt cctgctgtat taaatgtcaa atttctaagc tcaaatttag acctttctga
    12001 caaagatggc cctactatta caggaaaccc ttcttccact aattcatcta caataagatg
    12061 accttctgta caatggtcta atgtaagctt taaattaaat tcttttgcaa ttcttattgc
    12121 tgtaaacata tcatctgctc tatgagcatg tgccttaaaa ggaatttctc ttcttaaaac
    12181 tggtattaaa ctttccattt ttatatcata ttcaggtttt tcacagtctt catcatcatg
    12241 actctcatac atatcaatat cctctaaata ttcttctgct ttttttaggt tttctctaag
    12301 taaagcagct atagccattc tagtttgagg agatttatca tcctgaccat aacagctctt
    12361 tggattttct ccaaaagcaa ttttagatgc aactggattt tttattacca ttttatcaat
    12421 tctttttcca catgtcttta tagctataca ttgaccaccc ataacatttg cacttccagg
    12481 ggttgtacaa acagaagtta ttccaccttc aaaagcttct ttaaaagttc tatccattgg
    12541 attaattcca tctataggat ttaattgtgg tgttattggg tcagtctctt catttccatc
    12601 tgctccttca aaccctatac catcttccca taaacctaag tgagtatgag catctataaa
    12661 tccaggaaac acaagtttat tactagcatc tattacctct acatctaaag gagctatcaa
    12721 atcttctcca atttctatta tttttccttc atctataagt atatctccat gaattatccc
    12781 atttgttatg gtatttattt taccattttt tataaaaatc attcattttc ctcctgattt
    12841 tcaagactat cgttcttatt ttaatatatt ttcttactat atacttttac aaatttttaa
    12901 catttataca ctcgagtaat ctcatttaca aatatagaat ttaagtacta taaccataca
    12961 taaacttatc tattttttca ttgataaggc aactcttttt ttgtttaagt caattccaat
    13021 gacttttaca tctactatat cacctactgt aacaatactc atagggtctt tcacaaaact
    13081 attactcatt tctgatttat gaactaatcc gtcatttttt attccaatat ctacaaatgc
    13141 accaaagtct acaacatttc ttattgtacc ttttaaagtc ataccctctt gtatatcttc
    13201 aatttttaag acatcagttc taagtatagg ttttatacct tcttctcttg ggtctcttcc
    13261 tggttttttg atttcagcta tgatatcttt taacgtaact tgtcctactt ccagtttttc
    13321 acttaattcc ctcaagccaa tttcttttat tttttcatct atttcaccta tattcttatt
    13381 ctttacatca tctaaagaat atccaattat ctcaatcatt tttttacata tatcataact
    13441 ttcaggatgc acacctgtat tatctagtgg atttttaccc tctaagattc tcataaatcc
    13501 agcacattga gtaaatgctt gaggtcctag tctttttact tttttcaatt gtgctcttga
    13561 tgtaaaatct ccattttctt ctctatatgc tattatattt tttgctatag ctttacttat
    13621 tcctgcaaca tgttctagta gggagtatga tgcggtattt aaatctactc caacactatt
    13681 tacagaatct tcaacaactc catctagcac ttcttctaat ctctttttgt ttaaatcatg
    13741 ctgatattga ccaacaccaa tacttttagg gtctattttt acaagctctg ctaatgggtc
    13801 ttgtaatctt ctagctatag atatagctcc tcttattgat acatttatat ctggatgttc
    13861 ctcatttgca agttcagatg ctgaataaac agatgctcct gcttcactaa ctatcacata
    13921 ctgcacttcg ctatctattt cttttatcat ttctgataca aaagtttctg attctctaga
    13981 tgcagtacca tttccaattg aaattatatc tatatcgtat ttttcaatca atccttttaa
    14041 aactttcttt gctccctcta catcattttg agggtctgtt ggatatactg ttgtataatc
    14101 tagtagttta ccatttttat ctactacagc tattttacat ccagttctaa atgcagggtc
    14161 aaatcccata actactttgt ctttaactgg tggttgaagc aataaacttt taacattctt
    14221 tccaaataca cttatagctc tttcttgagc tatttctgtt aaatgatttc ttatttctct
    14281 ttctattgat gggaaaatta atcttttata agaatcttct attgaactta cgatttcttc
    14341 tttatttttg aaatttttat catttacata ttcgtttatt atgtaattta aaactttatc
    14401 attatttatt tctaacttaa cctttaggaa gctttctttt tctcctctgt ttattgccaa
    14461 aactctatgt ggagccatac tttttactgc ttcgttataa tcataataca tatcataaac
    14521 cgatttctca tcagtagcac ttttgctaac tatcatacct tctcttaaag ctaattctct
    14581 tatatacttt ctaatcttag catcatctga gactagttct gcaattatat ctctagcacc
    14641 ttttagagca tcttcaatag aaagaacttc tttctcttca tcaagataat tctttgcctc
    14701 tatttctata ttatctaaat tattctctag tattgacaat gctaaatttt ctaatccttt
    14761 ttcttttgct attgttgctc tagttctttt cttttgttta tatggagcat atatatcttc
    14821 tacttcttgt aatgtttttg ctttttctat attttgtgtt atttcatctg ttaatttccc
    14881 ttgttcatct attagtctaa ctacatcatc ttttctactt tgaagatttc tcaaatacat
    14941 taatttttca taaaattctc ttagtgtaac atcactcatt tcgccagtca tttcttttct
    15001 atatctagct ataaatggta ttgtatttcc ttcatcaata agttttaatg tattatttat
    15061 ttgttcatct ctaagattaa actctttttt taagatttga tttatatcca atttattcac
    15121 tcctaatgtt agtttttcat aagtataaca aaacagaacg aaggctgagg gttatcgtcc
    15181 tcagcctaag tgctgtaagt gcatattaag cactaacctt cttatacata tatcttaatt
    15241 acagtgcata tttattaaac tattttattc atttttaagt attcattaat aaacaagtct
    15301 atatttccat tcattacact atctacattt ccaaactcag catttgttct atggtcctta
    15361 accaatttat atggttgaaa aacatatgac ctaatttgac taccccaagt tatttgtgag
    15421 tatttgcctt gtatatcttc tattttttcc ttttgctcta actcttttaa ttctatcaat
    15481 ttcgccatta aaagtctcat agctctgtcc ttatttagat gctgagacct ttcattttgg
    15541 cactgaacta ctacaccagt agggatatgt gttattctaa ctgctgaatc agtagtattt
    15601 acatgttgcc ctccagctcc agaagctcta tatgtgtcta tctttaaatc tgacggatta
    15661 atttctactt ctatattttc atctaactct ggtgttacat ctatagatgc aaatgaagta
    15721 tgtcttttcc ctgatgggtc aaatggagat attctcacta atctatgaac tcctttttca
    15781 ctctttaaat acccataagc atttgttcct tctacaagaa ttgtagctgt ctttatccct
    15841 gcttcagggt ctgatattat atctaaaagc ttaactttat aacccttact ttctgaccat
    15901 cttatataca ttctcaaaag catttgagcc caatcttgag catctaagcc accagtacca
    15961 gcatttatag ataatatagc attattttta tcatactctc catttagaag agtctttatt
    16021 ttcatttcag ataatttttc ttccattgat tctatggact tttctatatc tctttctaca
    16081 gaatcatcat cttcttctaa acctatttca attaatactt ctatatcttc taataagctt
    16141 tttaagcttt catattcttc taatgtctct tttaaagatt tattttcttg aagtactctt
    16201 tgagcgactt cattatcatt ccaaaagtct tgttgattca tcttttcttc attaatttgt
    16261 atatttttca tcaatgaagc tatgtcaaag agaaaccctc aattcttcta aatttgaagc
    16321 catctgctcc atactatgtc tatactcttg taactttaac atttaatcct ccgagattat
    16381 cttccacaac agtttttata ttttttacca cttccacaag ggcataagtc atttcttcca
    16441 accttttcat cttttttaac agttttactt gttggaagtg ttccatctga tggagaagat
    16501 agattttcaa catctacaac tgcttttctt tccactggag tttctattgt tatattaaat
    16561 aaatatctta cagtgtcttc tttgatatgt ttattcattt catcaaacat atcaaaacct
    16621 tccattttat aagcaataac tgggtcttgc tgacctacag cacgaagacc aataccttgg
    16681 cgtaattggt ccatagcatc tatatggtct atccaatggt tatcaacagc ttgaagtaag
    16741 attactctct caacttctct cattctctca tagccaactt gttcttcttt tgaagtatat
    16801 atcttcatag ctatttcata aactttttct gttatttcaa ctggattaag tttttctatt
    16861 tctggtattt ctatgctacc ttttggcaag aacagattat acatatgttc tttgaatcct
    16921 tcttcatcaa atcctttatc ttgtgtataa agagtaactg cttcttctat tatagaatga
    16981 gtcattgatt gtatttgttc ttgtaaatct tcaccttcta atacacgttt tctctctgca
    17041 tatattattt ctctttgttt attcataaca tcatcatatt gaagtacatg ctttcttatt
    17101 ccaaagtttt taccttcgac tttcttttgt gctccttcaa tagacttaga taatattcta
    17161 tgttctatcg gcatgtcttc ttcaagacct attttatcta caataccaga tattctatca
    17221 ctaccaaaca atctcataag gtcatcatca agacctatat agaatcttga actccctggg
    17281 tcaccttgac gaccagcacg acctctcaac tggttatcta ttcttcgaga ttcgtgtctt
    17341 tctgtaccta ttatagcaag tccacctgct tctacaactt gtttttgttc ttcttgtgtt
    17401 tgttgcttaa acttttcaaa tagtttttca tactcttctc tagcttcaaa tagaatttca
    17461 ttacctttta caggtatacc ttctattgga gtatctaccc tatttactat ttcctcttta
    17521 aatccatttc ttctcatttc tctcttagtt aagaaatctg ggtttccacc taaaactata
    17581 tctgtaccac ggccagccat atttgtagct attgtaacag cgcctaatct accagcctgt
    17641 gctattatct ctgcctcttt atcatgatgc ttagcattta atacttcatg tttaatgcct
    17701 tttttcttta atatttgtga taataattct gatttttcta tcgatactgt acctacaagt
    17761 attggctgat taactttatg tctttcaatt atttcttgtg ctacagcatt aaatttacct
    17821 atttcacttt tgtatacaga atctggtaaa tcttctctta ccataagctt attggtaggt
    17881 acttggaaaa cgtccatttt ataaattgct ttaaactctt cttcttctgt ttttgctgta
    17941 ccagtcatac cagaaagttt tttatacatt ctaaagtagt tttggaatgt tacagtagct
    18001 agtgttttag attctctttg tattttaaga ccttctttag cctctattgc ttgatgtaaa
    18061 ccttctgaat atcttctacc aaacataagt ctacctgtaa actcatctac tattactatt
    18121 tctccatctt tagcaacata atcaacatct ttcttcatta ttacatgtgc tcttaaagct
    18181 tgatttatat gatggtataa ttctgtatga gatatatctg ttatattatc aacattaaaa
    18241 tacacttctg ctttttgtat acccgatgct gttagagata cagccttatc tttttcttct
    18301 aattcataat catctggttt taaggttaaa acaaatgtgt ttgcatctga atataagtga
    18361 gttgatttgt ctccaggtcc agatatgata agtggtgttc tagcctcatc tattagtata
    18421 gagtcaacct catccactat agcataattt aatcctcttt gaactctttg ctctttgtgt
    18481 attaccatat tgtcctttag atagtcaaat ccatattcat tatttgtacc ataagttata
    18541 tcacaatcat attgttcttt tctaactttt ggattttgac cgtgtataat aacgcctaca
    18601 ctcattccta aaaactcata gatttttgcc atttggtctc tatcacgttt tgcaaggtaa
    18661 tcatttactg ttacaacatg tacacctttt ccagtaagcg cattcaaata aacaggagca
    18721 gttgcaacca aagttttacc ttcacctgtt ttcatttctg ctattcttcc ttgatgtagt
    18781 actatacctc caatcatttg aactctgtag tgtctaagtc ctaacactct cttagaaact
    18841 tctctaacta ctgcaaaagc ttctggaagt atatcatcta tactttcacc atttgctaat
    18901 ctttctttaa atatatttgt catattttta agttccgagt ctgccataga ttcaaattta
    18961 ggttctaatg aatctattat atcaacagtt ttattgaact tttttaattc ttttttatct
    19021 gccatgttga ataaattatc cataaagctc atattttaca tctctcctcg ttctttattg
    19081 tactattatt cattttacca taaaaactat acttttaata ttaatttaaa aagctatcga
    19141 taatttattt atcgatagct aatatgatta aatctaaatt gctttattca tgttctatta
    19201 taccatatcc accattatta cgcttataaa ctactgctat ttcatctgaa tctatgttct
    19261 tgaacatata aaaatcatgt cctattaatt ccatctgtaa tacagcttct tcttcactca
    19321 ttggcttaac actaaatttc ttacgtcttt gaattactaa ttcttgattt tcatccccat
    19381 aatcctcttg ttcatcagct agatttatct ctgaatcttg gaatcttata ctcttgttgt
    19441 ctttatgttt atcttgtaat ctctttttat atttttttaa ttgtttactt aatttatcat
    19501 atacaacatc tatagctgtg tataaatttt cctgcatatc ttctgctcta attataggac
    19561 catttacagt agctattgtt acttctattt tttgtcttgc ttttctcgca cttactgtaa
    19621 cttttacatc agtgtctgga tgaatgtaat tatctaactt acttagttta gtttcgattt
    19681 tattttttat tgcatcagtt aattcgattt gttttccaga tataattatg ttcataaata
    19741 catctccctt caattatgtc agtataagaa aatttatact ttaataatat attctacacg
    19801 aactctcata atcctctttt tattatttac ttttatgatt ttttctattc aattgataga
    19861 attatttatc atttttagtt acattgatac ttatgtggat taatattatt acaaacacct
    19921 gtggataatg tggataaaac tgttaataac tcttgttttt gtttatttaa agctattttt
    19981 actcctattt ctatccacaa aaatctccat taattgttta ttaatatgtg aattcatgtc
    20041 ataagatggt aattttagga aattatgtgt attatatgcc aatatacctt tataattttt
    20101 taataactat aaaccctcta aaacctccat aatctatctt ttctttcatt atttatattt
    20161 aaaactactt aaaagttata aagcatactc aacaataatt tcatatttaa tacctattaa
    20221 cattcatata cccaaattat aattaactta ctctctttat ttaaactaag tattttatat
    20281 tcatatacta tcttgaaatt atatttacga gttgtttaag cttttgtcta tctatatctt
    20341 caaaaggact gttatttatt ctaatcgctg taccaaaatg aaaattactt gctttagtta
    20401 attcctttat cttttctata ttattaaaat taagacctcc tcctaaaaga atttttatgt
    20461 gattagaact aagcatcata ttctttatca tttgtatgtt atcaactata cttcctttcc
    20521 ctcctgatgt taatatattc gtaattttat cataatcctt caaaatttta acactatcta
    20581 ttgtatttga ttcatctatg gctctatgaa atgtaacatc aagattatca caacatttca
    20641 ataaaacatt tagatttttc tcatctatat tattgttttt atccaataca ccaaatacaa
    20701 ctccattagc accaatctct ttaaccacac ctatatcttt ttgcattata cttatatctt
    20761 ctttactgta tacaaaactt ttcgcatgat gtcttatcat tacgttcaca ggtatcttta
    20821 cactgttaac aacactttct ataagaccaa aacttggtgt caatccacct tcagttaaag
    20881 cactaactaa ctctattcta tctgcaccac aatcttctat aattttagcg tcttctactg
    20941 acattcctat tatttctaac ataactactc ctttgctaat tcatatattg catttgcaaa
    21001 tatctttgca tttaatatta tatcttctat atccatgtat tcatcaggat tatgagctat
    21061 tcctttttgt cctggaaatg aaggtccaaa cggaactata tttggcatta cttttgcata
    21121 cgtacctcca ttagttgtca cgggagttcc atctaatgat gtaacccttt cataagctag
    21181 ctgaagcttt ttaacaagat tactctcttt atcaaaatat acaggattaa aattagaaat
    21241 tacctctata tcgatactat ttggaaaact agcttttatt tcatctaata catctttcaa
    21301 tttataacta aaatcgtatt ttacctttat atctaatata gtattactat tttctatatt
    21361 cagctcttta tatgtaacaa gcacattttc agacatattt tctataaaac ctaggtatac
    21421 atcttcttca taattgattt tactttttat tctaatcttt gccatgcctt tttcaccata
    21481 tacaacagga tatttacaat ctggtgtaaa tcccataata ggtgtttttt ctttttctaa
    21541 ataatatggt atatcttcaa atccactttc ttcatttgta ccaaatatta ttctaactct
    21601 cttatctaat tttaagttta attctttaat agcatataat ccatataagg cagacattat
    21661 aggtccttta ttgtctagta ctcctcgtcc ataaattctt ccattagttt cttctccctt
    21721 ataaggctga tgcttccaac catctccttc atgtacaaca tctacatgtc caattacaca
    21781 aacataatca tcactatctc catgctctgc ataaccaata taattatcca agtttctaac
    21841 cttaaatccc aatttttttg atatttctaa tgctttatta agtgcctccc ctactttttc
    21901 gccaaaaggg aagccatttt ctgactcccc tttgacacta ggtattttta caatatctat
    21961 aatatcactt aataaatctt cttttaactc atctatttta ttacttatga tattcataaa
    22021 aatctcctta ttataaaact ctattttaat tatgtaacac tactttactc acttacttct
    22081 atcggtgctt ttattctagc ctcatatgct tccatccact catttgatat aaccttatgt
    22141 atagtctttc catctactct atttgaaata tatacagcag gagattcttc tttagttact
    22201 actgaaaaag tgaaatcaac tatatttgta gctactcccc attcaccttt attattcatg
    22261 gcaactaatg ataaatcacc agcttttcct cttcttttga taagctgttt atcaagttca
    22321 tttactgcaa tatcacatgc ttcttgtgga tgctttcctt ctttcataag cctaactatc
    22381 tcataagata tacatccctt cattaaatct tctcccaaac cagtagctgt agctcctcct
    22441 atactactat caacatagaa tcctgaacca gatagtgcag aatctcctat tctacctctt
    22501 ttcttcataa acaatccact tgttgatgta gctgcacaca tttttccagt tttgtctaaa
    22561 gatatcatac caacagtatc atgaccagca tatgggctta atcctttgtc taaagtctct
    22621 ttttttctct ttttataatg taacttcgct ctatcagtca acatattttt tctttcaaat
    22681 ccatttttat gagcataatc ttcagcacct attccaacta aaaaattatt taccttctca
    22741 taacttaact tcctagctat gctgacagga ttagaataat ctcttatacc agcaactgcg
    22801 ccaatatcta atgtgttacc atccataaat gcagcgtcaa gttctacctc acaattttca
    22861 tttggaagtc caccatatcc aaccgattta tagaatggat agtcttcaac tcttcttaca
    22921 gcaagctcta cagcatcacc tgcttccatg cctttttcta aatgttctga tgcctcagtt
    22981 attccttcta gggccattct ccatgtcgct atcattcccc acatgttaaa attcccctcc
    23041 ttaaattata tagattttac taatgtatgc ttattataaa tagtataata tttaaacttg
    23101 ctaataatta atactcttat taataacaaa attcttcttt catcaaagtt atatcttctt
    23161 tattcgctat tgcttttgcc aatttacata tgttatttaa tgaatcatta agaccaattc
    23221 cacctttttt gggagtctta actatacata tgtcattttt atattcgttt atcacatcta
    23281 tattttcttc tgacatagct gcaaaagctg gtatatctgt tttatcattt atatttttag
    23341 acagtattgc tgacatctta gaaaagtttt cgtaattaaa gcttggtcca cagattacta
    23401 catcagggtt taattttttt accatagcta tcatcttact cgttacttct ttttcattat
    23461 ttacaaaaaa ttcatcccca caaaataagg tagctattac cttagattca tttaaaaatt
    23521 gctccatcat tacacctggt cctaatgggc ttgattttcc agcaggaggt atattacttt
    23581 tctcttttcc tccagctcca gcttgtattt gatccaatat cataactatt ttcttcataa
    23641 tcttcctcct ataatactaa atcatcaaaa gatatatcat catcttcctc ttcaacagtt
    23701 tcattttctt ctctcaagta ttgcttatct agcattttta taaatggtat atacataaat
    23761 attcctagta taagaagcac taattgtaag actgcacctt gccatcctgt tgttaaaaaa
    23821 ccagagaata taattggagt tgtccacggt aactgaactc catttgtaag aggcactaat
    23881 cctgctgaca tacagaagta agctattatt atatttattg ttggaactat tgcaaatggt
    23941 atcaatagta ttgggttaag cattattggt agaccaaata tcaatggctc atttatacca
    24001 aatattcctg gtaaaattga tagttttccc attgacttta tacgtttact tttacatatt
    24061 aataacatag ctatgactaa tgatagtgta ctacctgctc caccaaatgt cgcaaacata
    24121 tcttggaatt gacctgttat tatgtttggt atttttgaac cagcctgaaa agcagctaag
    24181 ttttcagctg atagaatttt taatattgga ttatacacag ccccaacaac actacttcca
    24241 tttattccaa agaaccagaa taaatgtaag aatatataag cgattgccat agcacctaaa
    24301 ctatttccta attttaataa tggcatttgt aaaaacttaa atataaattc atgtatactt
    24361 ccatatggtg tagcttcaaa agctatctta actaaaaaga aaactaccat aactattgca
    24421 cttggtatta atgctgcaaa tgattttgat acggttggag gaactccatc tggcattttc
    24481 aatgtccatc ctttttttac aactgcagca aataatttta cagaggttat tgctgttatc
    24541 atacctacaa acattccctt agagcccatc caacctagtg gtatacctgt taccatgtag
    24601 actgattctg ttccttctgg tgtatatggt attacaaacg gtgttactat aaaaaaggca
    24661 actattgcaa ctgcagctga tgctattgga tctacatcta tttgctttgc ataagaatat
    24721 ccaattccta aaactgcaag taaagtcatt acttcaaatg ttgctacagt tggttgttgc
    24781 aattttacag cccaatctgg accaaaaatt tgacctacaa attcattcca tccttttata
    24841 ggaaaatttg ctactaataa aaataatgaa cctattatta ataatggtga tgatattaaa
    24901 aaaccatctc taattgcaat taataattta tttttaccta ttttttcagc caatggcata
    24961 agtattcttt ccaatctatt catctatcca ccctcatttc ctattatttt ttactataat
    25021 tctacgcttg tttagatttt attagcttta tagcaagttt taatactttt tccccattca
    25081 tagttccata atcaacttca ttgattatat ctataagttt tccttgagct tcaaactttg
    25141 gttttaactc ctttagcatg tatttaactt gtggtcctaa taatatacaa tctggatttt
    25201 tttcttcaac tattttgtca atttctgcta tcggaaatgc ctctacttct attggtaaat
    25261 tgtgttcatc tgctaccttc tgcattttat ctgcaagtaa acttgttgac ataccaaagc
    25321 tacaaaataa atatactttt cttttcattc ttttaaatcc cccttaattt ttttatttta
    25381 atttttgaat ttcttttctt aacataatca tttcttttat aaggtttctc tcactcatac
    25441 aagtcattaa atggtcttga gagtgaatca ataaaataga tatatctgat ttatctcccc
    25501 cagcttcctt ttgtataagt tcagtttgta ctttatgtgc ttttaaaatt tcttcatttg
    25561 cattttcaat taattcatct gcttttttaa aatcgttttc ctttgcatag tcaagtgctt
    25621 cataaagcat agattttgca tttccagcat gaattataat ctttaaaact atttcttcca
    25681 ttttttcctc ctaaattgct tctctacttt tagattattt ataccttaca aacatataat
    25741 atcttataaa aacaaaaaaa catgcacaac tttttccatc acatggaaaa ttttgtgctt
    25801 atccatagtt cattatgaat tttatataag aatatctttt accttttcaa tgtcacattt
    25861 acttagaata tctagcatat tttcatcctc tgttaaatta gatatttctt taaataattc
    25921 tctaaatact tttctatcat catctttttt atatgctaat aaaagtataa tctttatatc
    25981 ctttccattt ctaattttta ttggtgtttt taaccttgca aaacataaaa cagattgttt
    26041 tatatatttc atgtctccat gagggaataa tattcctttt ccaacattgg ttggatatga
    26101 cttttctctt gttataatag attgtaaata ctctttttct gcataatgtt tttcaattaa
    26161 taaattagtt aaatatgtta tagcttcata aatatcatca tgttctaact ctcttattaa
    26221 ataatcagac atcattaatc tgttcataag tttatatgag gtgtcttttt cttttatttt
    26281 gtttgtaaac tctttaagtt tattctcatc ctcatcagta aataatggtg ttgttataaa
    26341 aattggtttt tggatatttt catactcttg aaatgcaatt ataaaatcta tagtcttatt
    26401 aaagttatct ctttttaaat cttcctctct taatgtttca ataattttta tgttatcaaa
    26461 tctcttttct atctttactt ttaatagcat acttactcca aaactaaatg gacatacaat
    26521 acttgccttt ttatttgatt cccttttgct gtattttctt tctagagagg tttgaaagtg
    26581 aagtgtaaga taaccaattt catcttccgt tatttgtttt ccttttaatt caatttctat
    26641 tgaacttgat attactgtaa ataaaaaaca aaatttagtt tttatgttat ctaaaagtgg
    26701 attttctaag taaacattgc ttttcatttg atgcattgta acattcaaat gacatattaa
    26761 ttgttcataa agtaatatat cattattaaa atttattcct gattcttctg atactaaatt
    26821 tataattttt tttgtataac ttgctaattc ttcatttaga tataaagatt tcttaatatt
    26881 attactattt atttgtttgt tcatacccaa tattaaagat tctataaaca atttttcttc
    26941 ataatttaat actatggata aattagattt caattcatct tctatatcca atataagcat
    27001 ttttagctta agctctttct tagtatttga tacttttaaa gaatttccca gccttattcg
    27061 tattatattt ataagcaaaa atagcatcaa ttgcttgaat gatatatctg taagtcttat
    27121 atccatatcc tcctctatag taagcattat gttttttaca attattatat ctactatatg
    27181 gaagtactct atttcatcta tgtttaatct gtatttatct atgtatttaa ataagaatga
    27241 tactaacatt attcttatgt ctttctcatc cccttcaata tatataccac tgcctttttt
    27301 agtcgagaca tttaaattat aattatttaa tgctactgat aatttactta tttcttctct
    27361 gacaatattt ttatttatgt acaacttatt agataaatca tttaaagtaa cttttttatt
    27421 attacaaagt agtaaattta atatctcaac ttgcttatga agctcactat ttactctttt
    27481 aacttcacct cgcaacttct gatttaccag tattttgtct gttccatctc cactaaattt
    27541 aattccaata ttaggttttc ttttgatata agcattacaa aaagtagata accattcatc
    27601 aatatatttg caatcattcc ttattgtcct ttctgaacac tcaaaatcat tggcaatctt
    27661 attaacattt ataaactctt cttttaatag caatgttgtt aataaatttt cttgtctttt
    27721 attcaaacat atcacctctt tatgactcaa cctaaattta ttatatataa aaaagagcta
    27781 tacataaagg tatgctagct ctcttttaat atgatattta gctgacctgg tttttgaccc
    27841 cacactcgcc tactggaggg ttcgcttggg ttcgccgcac tactactctc tctcgatttt
    27901 attatcggta ggtcttactt ctaagccgca ccatgatcat taacccaatt tttagtgtta
    27961 acttacgtgg atccctttgc ctgcgactgg cttggacttt caaccacaga cctaaatatc
    28021 acttattcat tttaatattt taaactaaaa ttgtcaatat ataagattat tccataatat
    28081 aattatcatt tgcttttgta agtagagtca atacaaaaac cttattagca cctgataact
    28141 ttaaaagttt agagatttcg tttgttgtta gaccagtagt aaatatgtca tctattaaaa
    28201 gtatattttt attatttatt aatttaacat tttctttaac aacaaataca ttttttaatt
    28261 cttcttttcg ttctttctta ttcaatttat atagcattct tgtatatttt tttctactta
    28321 tgcaatctaa taatggaata tttactattt tacttaaatt aaatgctatt ttttgtgcct
    28381 gattaaaacc tcttttattt agcctttttt tatgaagtgg aacaaataat atataatcaa
    28441 attttatgtt ttctaaatat aatttttctt tcattatttg agctatatac ttagccataa
    28501 aggttttttg gttatacttc agccctaaca ccatcttttt tgtcacatca ttatattcaa
    28561 tacaagatat tgatttatca aaataaaagt ctttattaaa acaataacta cactcttcaa
    28621 taaattcttt ttcaattgaa tgacgtatta ttggttttcc acacttcatg caaccatctt
    28681 gtataaaatt catttcttta aaacaacttt tacatattga ataagtattt gttttcttta
    28741 tggatttatc acaaattatg caacttatat tctcaggata tataaaatcc aaacatttat
    28801 taatcatatt tttaaaattc ttaataaaat tatcattgca tattttcata tttattctat
    28861 caacaaccct tcttgtttaa atttatttag cttatatcct aaatttgaat acctttgatt
    28921 aactctatta ttttttatca tatattcaag atatttcaca tctccaacta atacaactaa
    28981 tttttttgct cttgttactg ctgtatataa taaattacgg ctaagtaaca taggaggagc
    29041 ccacgctatt ggcaatacta caactggaaa ttcacttccc tggcttttat gtattgttgt
    29101 acaaaaacta tggtcaattt catctaattc atcatatagg tatgatacaa ttttagtctg
    29161 gtcaaataat atataaatag ttttcttatc tttatctatg tgataaacat atcctatatc
    29221 tccattatag ataccttctc cactttcttt ttggtcttct gtttcccatt tttttgtata
    29281 attatttttt acttgcatta ccttatcgcc aactctaaat aatcttttag aaaaactttc
    29341 ttcaacttta aatttttctt ttttgttaag atacttctgt aactctatat tgagattagt
    29401 aactcccaat tcaccttttc tcattgaaga taaaacttgt atatctttta atttatcaac
    29461 tttataaaat ttaggtaatc tttcattaac caatcctatt atttcattta aaatttcttc
    29521 attagttgat tttcttataa aaaagaaatc tttacctttt gtatttagat aaagtggttc
    29581 tccattgttt atcttatggg catttacaat tatcatactt tcttgcgctt gtctaaatat
    29641 ttcatttaat ttaactacat ttataatatt agaattaatc atatccttaa gtacatttcc
    29701 agcacctaca gaaggtaatt ggtcactatc tccaactaaa attactcttg ttcctaactt
    29761 tatagctcta agtaaattgt acattaagat aatgtctacc attgatacct catcaacaat
    29821 tattacatct gaatttattg ggtcttcttc atccttaaaa aaagttaaat catcatctgt
    29881 tgaaaatccc atttctagca acctatgtat agtttttgct tctttattag aagtttcact
    29941 cattctcttt gctgctcttc ccgttggagc tgccaaagtc acacttttac cattattttc
    30001 aaatatatct atgatagcat taatggtagt tgttttacca gttcctggtc caccagttat
    30061 aattaatact ccactattaa cagattcttt gactgctaaa atttgttttt ctgctaactt
    30121 aattttctta tcttcttcta aaacattaat ctcgttatct atatctattt ttaagtcttc
    30181 aaattcatac tgtgataatt ttactatttg actacatact ccattttcag ctaaatagta
    30241 tggcataagg tatataagat tttcattgtt tactttctct atatgtattt tttgattata
    30301 aactagcatc attacacact cttttattat ttctccattt agctccaata atttttccga
    30361 atcttgtatt agaacatgct ctggtaaata tgtatgccca ttacttaaag atttatttaa
    30421 agtgtataag attccctgac aaattctatc tttagagttt ttatctatac caattttact
    30481 tgctatacta tcagctactt taaatccaat tcctcttata tcttcagcaa gttggtatgg
    30541 gtttttattt ataacttcta ttgcactgct tttatatttt ttatatattt ttaggcagta
    30601 atttggtgtt attccaaaag gagatagctg tattattata tttctcaatt ctctgtcttc
    30661 ttcataactt tttactattt gttttacttt tttactccct ataccttcta cttcttgtaa
    30721 tttttctggt gaattttgta tcacctctaa cgtatctaca ccaaacttat caattattct
    30781 ttttgccatt ttttcaccaa taccatgtat cattccagaa gataagtaaa cataaattcc
    30841 ttctaaggat gatggcgtta ctggcataaa actattcact tcaaattgag tcccataaat
    30901 cttatgattt acccactttc cttcaacttc tatgctttct ccaattgcca aagtaggcat
    30961 acatcctaca accacaattt catcattttc atttaccagg tgagctattg tataaccatt
    31021 atcttcgttt ttaaagacta tttcacttat cattccttct aatttttcca tttttatctc
    31081 ctaaaaatac taataatcgc tccatttaaa tgttagtata attttatata ttaaaactat
    31141 gataatcgta gaaaagtttt atatttttat acttaacgta atttccaact attatacatt
    31201 ttatcagaaa caaaaaaaat ctgcatccat aaaatatggt accatgaaat acaggtacca
    31261 tatttaaata gctattttat tttaattact ctatatttag agtataaatt aaattccata
    31321 agtatattac agtactaact tatttcagat ttattctcct tgtacccctc agttttagta
    31381 attcttctat aaagcataca tagtaaaatt aaaattccca tgtaacctgt atatggatat
    31441 agtgtaccta ctaacttatc aaatggcagt aaacctccta tacaagctaa tatacttacc
    31501 actattgtta taattttaaa tttagggtgg tcatcttcta caaatcggtt agttactgac
    31561 cataacaatg gtacagctgt agtgtatatt cctagtaaaa gtactactga gaataaaata
    31621 cctattattg gagatatctt atcagctaag taaagtgctg gtatctcttt tgtgtatata
    31681 tttcctatgt ttgaaagtaa tgccaaattc atcattatag ctgctgccat aagtgctact
    31741 ccacctacta taccacccca tacagcatct ttcttattta ctgcagaagc tcccattcct
    31801 gtcaagaatg ttattactat tattacattg taacaagtat aaagtactcc cgagaaatat
    31861 ccatttgatg tagcagtttt aatatttaaa ctatcaacca tatttccagc atttgataaa
    31921 gcatcaatat tgctaaataa actaattgct cctactaaaa gtgtaaatat tattattata
    31981 ggtcctatat tacctagtat tttagaaagc cttgtcaaac ctaatgaaac agttattagg
    32041 gaaacgattg ccataccaat cctacctaca tatggattta atccatagta ctctgatagt
    32101 gtagctcctg ctcctgcaat cattattact aatgttccaa ataaaaacaa tggaccaaac
    32161 cattcaaaaa atgttccaag atattttcca caatatactt gataaatttt tattggctcc
    32221 ttaagtttca attctcttcc cttatctata acttctgctc caaaccatga aaatagtacc
    32281 atagagatta ttccacctat aatacccgca tatccataaa acgtaaaaaa ttgcagtatt
    32341 tcttgaccag ttgcaaatcc agaacctatt acagtagcaa cataagctcc agcaaaactt
    32401 ataaccgttt taatatttac tttgcctgac atacactact cccccccaat taaaattatt
    32461 tttaaagtgt aagtttatta agattatatt agactcatta ttgtgatatt tcaatatatt
    32521 tttaattatt taacattagt taacacattc ttaaccatcc tttaacatat atcccataat
    32581 atgtataaat ttagtagagt attatataaa atgtattgac cagattaaat actgtttatt
    32641 cattatatga tgataaatta acatttatta aaaatattta actcataata aaaaaactgt
    32701 tagaaagtaa tcgtaaaatt acattctaac agctttttag ttaaaaatta ttcacctaaa
    32761 gcatcttttc ttaactgctc aaccttgtca gttctttccc aaggtaaatc tatatcagtt
    32821 ctaccaaagt gaccataagc agcaaccttt ttataaagag gctttcttaa atctaagtct
    32881 cttattatcg ctcccggtct taaatcaaag tgtttattta ctaattcaac aagtttttct
    32941 tctgaaacct tgcctgtccc aaaagtatct ataaatatag ataatggtct agctatacct
    33001 atagcatatg caagttctat ctcacatttg tctgcaagac cagccgcaac aatatttttt
    33061 gcaacatatc tagctgcata agcagcagat ctatcaactt ttgtagggtc ttttcctgag
    33121 aaagctcctc caccatgtct agaatatcca ccataagtat ctattattat ttttcttcct
    33181 gtaagacctg tatctccttg tggtcctcct ataacgaatc ttcctgttgg atttatataa
    33241 attttagtct cttcatcaag taattctgct ggtataactt ccttaataac atgattaatt
    33301 aaatcttctc ttattttatc atttgatact gtttcacaat gttgagctga tataagaact
    33361 gtatgtactc ttacagcttt acttccttca tattcaacag taacttgagt ttttccatct
    33421 ggtcttaaat aatcaactaa acctgttttt ctaacttctg taagccttct tgataattta
    33481 tgtgccaaag atatcggaag tggcattaat tctggagtct cattacatgc aaatccaaac
    33541 attatacctt ggtctccagc tccaactttt tctatttctt cttctatctc ttctccagtc
    33601 ttactttcta gaccttcatc aactcccata gctatatctc cagattgttc atcaatagaa
    33661 gttataactg cgcaagtatc acaatcaaat ccatattttg ctcttgtata tccaatttct
    33721 cttactgttt ctcttactaa tttaggaatg tctacataag cagatgtact tatttctcct
    33781 gctactaaaa ctaaaccagt agtaactgta gtttcacaag ctactctaga ttgtgggtct
    33841 ttttctaata atgcatctaa tattgaatct gatatttggt cacatatctt atcaggatgt
    33901 ccttctgtaa ctgattctga cgtaaataaa tgtcttgcca tttttattcc cccttattta
    33961 ttcttaattt ttattatagg ttttacctta tttttaattt tagaaattta ctcaaaataa
    34021 aaaaacctct cctttataag aagaggttaa taatcgtaat tacatactaa ttaactgacc
    34081 tcatctttca agacttttgt cttgtaggaa ttagcacctt ttcccatttg ggtggttgct
    34141 gggcttcaca gggcctatcc ctcagcctct cttgataagg taatcaagat ttaagttttg
    34201 ttttacttta ctagcttact atttttttaa aattttgtca atatttttag tcatattttt
    34261 tctattcctt tttttgtaag acaaataaaa ttttctatct atctgaaatt taaagttagg
    34321 tctttttaat gctttttatt catatatttt tttgaagggg gtgttcctat tgtatttagc
    34381 taaagtaaac tacagcgatg atgatgttat acagatgcta agttcagttc taaaaactat
    34441 aattaatgaa aatacgattg ttgtttgcat aggaacagac agggctatag gtgatacttt
    34501 aggcccttta gttggaacaa tacttaagaa cagtaacttt aaataccccg tttacggtac
    34561 actagataac cctattcacg ccttaaatat atatgagtct ttagatacta taaaaaatac
    34621 acatatacaa ggtaacttct tggctataga tgcttgcttg gggtcgcaga gtaacatagg
    34681 taatatacag attagagaag gacctatcct gcccggaaaa ggtgttggta aaaaactacc
    34741 tcaaatagga aattattcta tagtaggaat tgtagataaa attgatgaaa ataataaact
    34801 ttcatttaat aatatacgcc ttagctttat attagattta gctgaaacaa tagccttggc
    34861 tttattagta tccacctaat ctaaatataa actaaatgat aaaattcttt atataaaaag
    34921 gtagatattt tagagtatct gattaaatac tccaaattat ctaccttttt acttttatat
    34981 ttcaagtttt tatttttcta ctaaagcaaa cattaattca cctttacaga caagttcttc
    35041 acctacatat gccttagcat ctgccttagc tatatttttt ctaagagttg tcatttcaat
    35101 ttccatagtt aatgtatctc ctggtcttac ttctctcttg attctaactt tatctatacc
    35161 tgcaaataca cctagttttc ctttgttttc ctctacagac atcattgcca ctccacatac
    35221 ttgtgctaga gcttctacta ttagtactcc tggcatcaaa ggatattctg gaaagtgacc
    35281 ttggaaaaat ggttcattaa ctgttacatt ctttatacca acagctcttt tcccaacttc
    35341 tagctctgta atcttgtcta ctaataaaaa tggatatcta tgtggtatta atttttttat
    35401 ttcatctata tttaacattc taaactctcc taattatttt cttttgaaag acccaccagt
    35461 ttcaagtaag tctattgaac ctaaagctat tcctgtacct tttgcaacac aagataatgg
    35521 ttcatctgct attgtaacag ttattcctgt cctctgttct attattttat ctaatccata
    35581 taataatgaa cctcctccag tcattattat accgacatct cctatatctg ctgctaactc
    35641 aggaggcgtt ttttccaaaa cagcatgagt agcaactact atttgctcaa cacattctct
    35701 aagtgcttcc aacatttctg ttgaatttat agttatagaa ctaggaagtc ctgtaattaa
    35761 atttcttcct gttatcttca tatatttttc ttcttctctc ttaaatgcag aacctatttc
    35821 aaacttgatt ttctctgctg ttctttctcc tataagaaga ttgtgttgtt ttttcatata
    35881 tttaactata gcatcatcaa atctatctcc accaaccttt atagattcac ttacaacagc
    35941 tcctcctaga gatattacag ctatatctac agtacctcca ccaatatcta taatcatatt
    36001 accattaggc tgtgatatgt ctacaccagc tcctatggca gctgctattg gttcttctat
    36061 gatatatact tctctagctc cagcttgtct cgtagcatct tctactgctc ttttttccac
    36121 ttctgtgaca cctgttggta cacataccat aattcttggc ataaaaaatc ttccaaatcc
    36181 ctttttatca actatcttat ctataaaaga ttttaacatc ttctcagtta catcataatc
    36241 tgaaattaca ccatctctta aaggtcttat agcgactata ttacctggtg ttctccctat
    36301 catcttttta gcttcttctc ccacagctaa aacagaatct gttcttttgt ctatcgccac
    36361 aacagatggt tcttctaaaa cgattccctt accactaaca taaacaagca catttgcagt
    36421 acctaaatct atgcctatat cagctccagc cattttttca actcctttat ttataatatt
    36481 agattatatt ataagcctat tttaatactc ctataataaa gcatatacaa aaatctcgct
    36541 ttaatcaaga gaaaataaat cttttgagag tattattatt ttgctattta taattactta
    36601 atatatttct ttttataatt taattcaata aaaaaagtag gtttttaacc tacatttttt
    36661 tatgttcctt ctcatatttt aatttcgttg ctaatccccc tctaatatgt ctctctgatt
    36721 tatttttgtc cagcacattt ttaacttctt tggcaaggga tggatttatt tccttcaatc
    36781 tttctgtaac atccttatga attgtacttt tacttactcc aaatgtcttg gcggtttgtc
    36841 ttactgtagt gtttttttca agtatatatt ttgctaccac tatggccctt tcctctatat
    36901 gagatctcaa agattacccc cctcacataa tagctttaat gatatatatg taaaaacacc
    36961 aaaaaatata acaagcttaa ccaaatatga ttaaacttgt tatactttta cttaattaga
    37021 ctcattgggt ctatagattt ttctccacta tacgcctcta aatgaacatg tataccttct
    37081 tcactttcta tttgagaagt actacctaca gtacctagag attgtccttc tgttaccttc
    37141 tgttctttct taacactaac atttttatct agatttgaat atactactac aatgttattg
    37201 tcacttttta ttttgactga ttgcccatat tcttcatcat taaatacatc tactactatt
    37261 ccgtttaata gagattttac ttctttgcct ttagtacaac taatatctac acctttatga
    37321 gtttcccaaa catcaagagt tttagaataa ctaggttctt tttctgaata tcctcttatt
    37381 actttatctc caatgtaatt taattttgtt gtactcgatt tattttcctc ttttgactta
    37441 gctttttcta agttttgttt tgaatccgtt gcagtaggga tagcatcttt cttgtctttt
    37501 tcaattaaat gtatttcctc ttcactatct ttattagcat tttccataat tcctttatta
    37561 gaagccaatt tatctacatt attatttgta aaccaaactc cacctactgc taataaacaa
    37621 acacatacaa acaaagataa ataaaaacca tctttttcta acagcttttt cttcattttg
    37681 cacctccaaa tatatttcta catttggatt attgacgtgt ttttggcatt ttatacaatt
    37741 attagtatat atcttttatt tttgtatctg tgtagtaatg tgataatata tcataatatt
    37801 tatagccctc ttctgccatt ccttctgctc cccactggct cataccaaca ccatgaccat
    37861 atccttttac cacgaaatct atgtatcctt ctccaaattt tatgtcaaag tttgcagagt
    37921 tcaatttaaa aacagttcta atgtcttttc cagtcaattc tttatttcct aattttattt
    37981 tttctacagt tccggcatca cttcttttag ttattgaaac ttgtttactt aaattattca
    38041 catctatcac aatagtgcta tatgcccttc taagactttt aacaaaatct gtgttactta
    38101 ttttaagtgt tgacgcaaat ttaggggaat acttatcata aggactttcc acagacttta
    38161 aataaggata ttttgcagaa aatacttctt cactattttc tgtttttcct gaagatgtag
    38221 aaaaataaag aggaagtatc gccttatcat tataagttat tatttgacct ttagttcctc
    38281 taactgcttc ttggattttg gaatatttat tcttaatcca ttcttcacca tttaattttt
    38341 taagagtatc ataactctta tattcttgac aatgtttata atcagtacat actactgcat
    38401 ttttatgttt actagattta ccatgttcct gtttatatac tacatatgtt ctagctgcta
    38461 cagattgagc ttttaaagct tctatatcaa actctgaaga catctcacca gctagtactc
    38521 cacataaata gttctccatg tccatctttt cggttttccc tgttatatga ttatatacat
    38581 tgataattgg tgctttttta tttacagttt catagctcac tgtacttttt tcttctttat
    38641 tacctttgtc ttcaatatca ctttttttaa tagttttgtt tatagatact gggctctctg
    38701 gtttttcagt taattctaca tttttataag aaactaaagt tataagtgat ggaactaaca
    38761 cagagcaagt cacaaatcct aacaaaacaa ccaatgggtt cttcatatac tctcctcctt
    38821 agcttttaaa accttgtatt taagtatatg aacaacccta ttaatttata actttcttct
    38881 ataaaccaat tattaatctt ctactatttc gatttgacca cctagtgctg ttatcttctt
    38941 atctatatca acataacctc tttggatatg gtatatttct cctatttgag tttctccttc
    39001 tgctataaga ccgcataaaa taagggctgc ccccgctctt aaatcagtag cgtttactgc
    39061 tgcaccgtgt agctcatcta caccattaac aaccgcactt cttccatcta tttttatatt
    39121 agcacccatt ctattaaatt cagcaacatg cataaatcta ttttcaaaaa cagtttctat
    39181 aactacacca gttccattgg ctacagtaag catagccata aattgtgctt gaacatctgt
    39241 aggaaatcct ggatgtggta aagtttttat atctattggt tttaatactt ttggacctac
    39301 aactcttaca gaattgtcca tttctgttat ttcgcaacca gcttctctta atttagctac
    39361 aactggtttt aaatgctcca ttaaaacatt ttcaacagtt atatcacctt ttgtcatagc
    39421 tgctgcaacc atataagttg ctgcttctat tctgtctgga attacattat gttctgctcc
    39481 ttttaactct ttaacacctt ttatttttat agtattagta cctgcacctt taacatctgc
    39541 tcccatttcg ttcaagaagt ttgctaaatc tactatttct ggctcttctg ctgcattctc
    39601 tattattgta gtcccttctg ctaaagaagc tgccatcatt atgttttcag ttgctccaac
    39661 agatgggaaa tctaaatata atttatttcc tactaacttt tctgttgctg cttcaacaaa
    39721 accatggtcc atttctatct ttgcacctaa ggctttaaat ccttttaaat gtaaatctat
    39781 aggtcttgtt cctatagcac atcctcctgg catagaaatt ttcgtactat taaatctagc
    39841 aagcaatggt cccataacca aaaaagaagc tctcatcttt cttacaagct catatggagc
    39901 ttcacaagtt tttatattgc ttgcatcaac agtaagtgta ttttctttat attcaacttc
    39961 tgctcctaca tgtcttaata aatctgatat aacatgaaca tctcttaaat ttggtactcc
    40021 atttaatgtt gattttccgt ttgctaataa agtcgctgct attattggta aaactgcatt
    40081 ttttgcacca tctattttaa cactaccttt aagtggatta ctctttttta ctattatctt
    40141 agccatattt tttgatctcc tcataattaa taatctaatt ttataattgg tgtggcaata
    40201 tatatgagtg tttttccgtc atcctcatta tatttaattc ctatatttaa attaattttt
    40261 tcccctaaat attctaattc ataatcattt aatactttac tatatgctgt tatagataaa
    40321 aagtttacgt ctttaacttc atctatttgc ttagcactca tattatataa tattttttgt
    40381 aaaatatcat catatttgtt gttttgtaac ctttttgtgt attctccaac aatacaagca
    40441 gacacatcta cttgagatga atatttattt aacacatttt ctacgttact ataaataacc
    40501 tctttatgtt tatatacttt gttatccaat atgtcaacta ctatgtaact ttctttgtta
    40561 tttttattta ttccttttat agaaatttct ttatcgctac cttttatagt agcacataat
    40621 tgtattttat cgccagaccc tttttgattc caatttattc cttttttatc caactttaga
    40681 ttgttaatta tttctataaa aatattatga aattctttat ttgataaatt atgatttata
    40741 acagaattaa ttttaacatt ataaaattta aaatttgctt ctgatatttc aagagcttta
    40801 cttaatctat tgtatctagt atttatactt gtatctgcat aagatattgt cattcctata
    40861 atcattaata taaaaaagct tatagctaat tttacttttt tcatagtaaa aaatccccct
    40921 taaatatgtt tttctgtata atagaattat taacaaattt aagagagata tactttctca
    40981 atatgtattt ttatacattt ttgtattttt catctaataa tctctttcaa actcttcaat
    41041 ctcaattttc tctatccttc tcctggactt gccaattcct tatatgtatc aaatacatct
    41101 tgcattaatt cttatatatt atcttctgta atataaatta cttagtctat acttaaatct
    41161 ataatctata atctataatc tataatctat aatctataat ctataatcta taatctataa
    41221 tctattcata ttttaccagc aaaataaaca gataatactt ttttatcaat ttccatagct
    41281 ccaaatgaac atacctaagt acacttccca atacacaatt tacacactct tcctaataaa
    41341 tcaaaaacac ctttgtttta aacaactcta ttgtactttc aaaaacttta tttgtgttct
    41401 cccacttcaa ttaaatttga attatcaaga ctccagccca tccatccatc actataaagg
    41461 gaggtatttt ccactcctat gacatttgca tatgttaata cttcagcagc acgccatcca
    41521 cttccacaca taaatataag ctgtttattc acatctatat tttccttgtc ccacatttct
    41581 aaaatctcag atttatttct cattgtatta tcaatattac gatattcttc tagtgaaaca
    41641 ctattactac ctgaatgtcc atataaagct cctggtatac gccctttttt atcataatat
    41701 gtatatccag atacttttcc tatatgttca tcccaagtac gattatctac tagtataaac
    41761 ttattttttt cttttagttt ttgtcttaat tcagatgtag taacaactaa ttgtgagtta
    41821 actggtatat ctgctccaaa attagtacat gaatgttttg gattactaat aaattctaat
    41881 tcatatcctg ctgataacca tgagtttgtt ccaccattca aaactcttac atcttttact
    41941 cctatatatc tcaatataac agctagtcta taagatgcca taggtgtaat acttgaaact
    42001 attacagtat catcctttgt tagtccatag tctaaagcaa acttagttaa gttatcatca
    42061 ttatcaagca tccatgttgg aggaggttct ataatatcag tatttacatg aacacttgta
    42121 ggtatatgcc cttttgtata cgattcttct ccccaactcg cttcaatcat ttttatattc
    42181 tttgaatctt caaatgtctc aggaattttt ccatctaata tatcttttat tataaaagca
    42241 ggaactatca tttgataatt tttatatctt tccattggaa gattttcatc gtctgcccat
    42301 tgtttaatat catatttata tagatattta tatccttttt tagataaata atctgctaca
    42361 accaaagcat cttttccatt tgcatcatac aatactatat ttttatctaa atcaattctt
    42421 ttagttttca atgcttgttc tagcacttca tcttttctat ctgagtatac atttaaccaa
    42481 ttagcagaaa aatctactgc tctttttata tgcccacctc tttttactcc atctaacttc
    42541 cagccattat aagcatcatt taagcgagta tcaactataa cccaagcgtt atcttgcatt
    42601 ttttcttgta aaacttcagt agatattgcc ttaagattaa caaaataatc ttctttcttt
    42661 tcttttttaa aatcatttgt cataatttat actcccaatt taaaaaaatt tttatttgaa
    42721 attattttac taaaataaag taattttctt atactctatt agcttcatta tattctttta
    42781 taaatagttc cttatattct tattttaaac tactcacttt atcttatcac aaggttacta
    42841 ataccttgta ttttaatttt tctcataagc tattattttt ttatgtctga tattgactat
    42901 atgtttatta agtactcact atattttata tgaactatat ttatcgttcc ctatacctgg
    42961 tatggtctat atatttatca ttttacagat gatttaatat caatcttttt ataaaattta
    43021 ttatagcaaa aacaaaacaa atttaatatt tatctaaaaa actcatccta taaaatacaa
    43081 ataacaggat gagttttttt caataaatat tatctattta atttttaatc tgtttttatt
    43141 caactgttac tgatttagct agatttcttg gcttatctac atcgcatcct cttagtacag
    43201 agacatgata cgcaagtaat tgcattggta caactgctaa tattggtgat aaaatatcat
    43261 ctgaatttgg tatatagatt attttatcag cagctttctc aacatcctta ttatggcttt
    43321 gagctattgc tactacataa gctcctcttg ctcttacttc ttccatatta gaaaccattt
    43381 tttcaaataa cttttcttga gtagctatgg caattacagg agttcctttt tctattaaag
    43441 ctattgttcc atgctttagc tctcctgctg caaaagcttc tgcatgtata tatgaaatct
    43501 cttttaattt caatgaacct tccattgcta agctatagtc tatacctctt cctaaataga
    43561 atgcatgttc agaactaaca actgttttag caacttcttt tatatattct tcattgtcta
    43621 atatttcttg tatttttgat ggtatttctt tcatcttaga aatcatacta tcataaaatt
    43681 ctctagttat tgttcctttt ttgatagcaa agtctaaagc tatcatgtat aaagaagtta
    43741 tttgagtagt atatgcctta gttgatgcaa ctgctacttc aggtcctgcc caagtataga
    43801 atacatcatc tgattctctt gctatagatg aacctacaac gttagttatt gaaagtattc
    43861 ttgctccttt agcctttgaa tctcttaata ctgctagagt atctgctgtc tcaccagatt
    43921 ggctaactaa tattactaat gaattttcat ctacaaatgg gtcgctatat ctaaattctg
    43981 atgctatatc agttattact ggtatattta caaatttttc tatggcatac ttaccaagta
    44041 atccagcatt atatgctgtt ccacaagcca ctatataaac tttatttatt ttttctaagt
    44101 cttctttaga aatatttata ctgtctagaa ttatatttcc attatcatca agtcttcttt
    44161 ctaaagtttc tctaactcct gttggttgct catgaatttc ttttgacata aagtagtcat
    44221 atccaccttt agacgcagct tctacatccc aagttacatg aaatacttct ttttcaacaa
    44281 gatttctatt agagtcataa actgttacat tttcgtcttt tagatgaact acttctccat
    44341 tttctaagaa ataaacatct ctagtatatt ttaataatgc aggtatatct gatgctataa
    44401 agttttcacc ttcaccaaca ccaactacaa gaggactatc ttttcttact gcaactaatt
    44461 catttccatg ttctttacat ataacaccta atgcataagc tcctcttaat tttgatatag
    44521 ttttgtatac agcatctaat aaattaccct catagtattt atctactaaa tgtgctatta
    44581 cctctgtatc tgtttgagat tcaaacttaa caccttcaga aattaattct tcttttattt
    44641 ccatatagtt ttctattatc ccattatgaa caactgctat tgttttggct tgattaaaat
    44701 gaggatgtga gtttacatca gatggttctc catgagttgc ccatctcgta tgccctatac
    44761 ctaaatttcc atcaatagga ttcttttcta agtcttctgc aagtacagaa agtctacctt
    44821 taaactttct aatattaagt tcttcttcat tagaactatt aactgctact cctgctgagt
    44881 cataacctct gtactctagc ttagaaagcc cttctactat aacttctgct gcctttctac
    44941 ttcctaaata tccaactatt ccacacatta tttgtgtcct cctaaaaata ttatttatat
    45001 attttaagag ttaggtcata taagtttact ttggcttccc tttgtccata ggattgctcc
    45061 tattatttaa agaagtcttt cgatggtaaa cacaccgcag agcatccgcc gacaattcga
    45121 ttaactctga cctcgtcaac ttagttccta tattactcaa taattatgtc tataactaag
    45181 ttctggcgct tagaaaggtg tcctcagtat ttgtatctga gaataccctt taaattacga
    45241 taatttttct tgtataagat tagctaagtt tgttgctaat tcttttattt gaccttcctc
    45301 tttaccctct aacataactc taactaatgg ctcagttcct gatggtctta tcaaaactct
    45361 accatttccg tttaaaatag attctattct ttctatctca gtttttattt ctggatattc
    45421 catatatttg ttcttatttt cattttttat tgttgcattt actaatactt gtgggtattg
    45481 gctcattatt gatgcaattt ctgataaagg tttcttttct tgcaagatta tatttgcaag
    45541 tattagagaa ctaagcactc catctccagt agtgttgtaa tctaaaaata tcatatgtcc
    45601 agattgctct ccaccaagat tatatccatt tttaaccata tcttctaaaa catatctgtc
    45661 tccaactgct gtagtagata aatttattcc attttcctta gcagctattg tcaaccctat
    45721 attactcata actgtaacta ccaaagtatc ttgcgccaat ttattatttt tctttaaatt
    45781 taaggcactc aatatcatta tatggtctcc atcaacaatt tgaccctttt catttactgc
    45841 aattaatcta tcagcatctc catcatatgc aagacctaag tcagcattat gttccaaaac
    45901 agccctttga agttgttctg gatgtgtaga gccacattta tagtttatat tatttccatc
    45961 tggtgaacta tttattgaaa ttacacttgc tcctagttca tcaaacacta ttggtgccac
    46021 tttatatgac gcaccattag cacagtccaa aactactttt aatcccttaa agtcagtgct
    46081 tattattgat tttaggtagt ctacatagtc tctttgtgca caatgttcat gtaattttct
    46141 tcctacattt tcaccaattg gaagacaatc aattttgtct atatcgtcta tatattcttc
    46201 tattttcaat tcaatttcat catctaattt atatccattc ttattaaaga atttgattcc
    46261 attatattca acaggattgt gagatgcaga tataaccaca ccacaatcag caccatattt
    46321 tctagttaaa tatgccactg caggtgttgg tattattcca acagtaataa catcacatcc
    46381 aacagacata agtcctgcta ttaaagatgc ttccaacata tcacctgata ttctagtatc
    46441 cttacctact actactttta ctctgtggtc tccttgagct aagacaaatc caccagctct
    46501 accaagttta tatgctaaat cacatgttag ttctgtattt gctactcctc taactccatc
    46561 tgttccaaaa tactttctca ctaaagattc tcctttcata attgaaaagc ttgtaatttg
    46621 tattatattt ttatagttca taaaatatca ttataggctt aatttcagtc ataaaaacat
    46681 tttaatactt atcagcaaaa aagacaatag aaataattct attgtctttt ttttgacatc
    46741 tttttcttta ttagttagtt gctttagaac atgtagcatc catacctttt tgtaaagctt
    46801 ctctgtttaa tggaacgaat ttttcttttc taggtccgaa aacttttttg aatgcttcta
    46861 gtacagattc tatatctaca gtatcagata cttttaagta agcgcctaac attatcatat
    46921 tagcaacttt atcatttcct aattcagctg ctaattcatt tgctggtata taataaacat
    46981 ctacatctgt tctatcaact ttttctttta ttaaagaact atttactatt atttttccac
    47041 caggaataac atcatctttg aatttttcaa atgctggtat atttaataat atagctgcag
    47101 ttgcatcatc tgttataagt ggagaaccaa ctggctcatt agatacagtt actgcacagt
    47161 ttgctgtacc tccacgcatt tctggtccat aagatggtaa ccaagaaact tcttttcctt
    47221 ctagcattcc tgcataagta agtaattgtc ccatagacat aacaccttgg cctccgaagc
    47281 ctgcacatat tactctagct gtagacattt acttcacctc ctcaacttca acatttttga
    47341 aatttcctaa tggatagtat ggtatcatgt tgtctcttaa ccattgtaaa gcatcgtttg
    47401 gagctagtcc ccagtttgta ggacaagtag ataatacttc tactattcca aatcctaatc
    47461 ctgcttgttg aacttggaat gctttcttta tagctttttt agcttgtcta acatgagctg
    47521 gagtatcaac tgctactctt tctacaaata cagctcctgt taatgtagct aacatttcac
    47581 ttactcttat tggataacct tgagtttcag catttcttcc tgattgagca gtagtagctc
    47641 tttgtccaac taatgtagtt ggagccattt gtccaccagt cataccataa gttgtattgt
    47701 ttacaaatat agtagttatt ttttctcctc tagcagctgc atgaactatt tcagcagtac
    47761 caattgaagc taagtctcca tcaccttgat aagtgaatac tgtattttca ggatgaactc
    47821 tttttattcc tgtagcagca gctggcgctc taccatgagc agcttcttga gtgtcacagt
    47881 taaaatattt atatcctaaa actgaacatc caactggaac aacacctaca gcatcaccta
    47941 atactcctag ttcttctaat acttcaccaa ctaatctatg gattatacca tgtgtacatc
    48001 ctggacagta gtgagtttga gtatcttgta atccttcagt tttcttaaat acaacagcca
    48061 ttatctagca cctcctgcaa ccaattctcc ggcaataatt tttttagctt tttcaactat
    48121 ttctgctggt gttggagtca ttcctcctgg tcttccatgg aagtaaactg gtaatttacc
    48181 ttctactgcc attttaacat cttccaccat ttgtcccata ctcatttcaa cagtcaatat
    48241 gtttctagca ttaggaattt ggttgaatgc ttcgaatggg aatggccata atactttagg
    48301 tcttataaga cctgctttta ttccttcttc tcttaatata tcaattgcgc tttttactac
    48361 tcttgaagta gttccataag ctgcaaatac aaattcagca tcttctgttt tgtacatttc
    48421 gtattgtact tcattctttt ccattgcatc aaatttttct tgtaaatgcc aacaatggtc
    48481 ttctagtact tctggttcta agtatagaga gtttattaca ttaggttttc tttttccttt
    48541 agttccaaca gttgcccaat ctttaggagg caattctctt ttcttctcag gagctctaaa
    48601 ttcaactggc tccatcattt gacctatcat accatctgca actaccataa ctggtgatct
    48661 gtaataatct gcaacgtcaa aagcttccat tatcatatca acagcttctt gaactgtagc
    48721 tggtgcgaat actggagttc tgtagtctcc atttcctcca cctcttgtag acataaagta
    48781 gtcagcttgt gaaggttgta tacttccaag tcctggacca cctctcatta cattaagtac
    48841 aacacaagga acttctgctc ctactgcata tgttatacct tcttgcttta aagcaactcc
    48901 tggtgaagat gaagaagtca taactcttgc tcctgcacct gctccaccat aaaccatgtt
    48961 tatcgcagaa acttctgatt cagcttgaac gaacgctcca cctattttag gtaactctct
    49021 tgataaatat tctggtaatt cactttgtgg agttattggg taaccgaaga aatatttgca
    49081 accagcttct atagctgctt ttccaaatgc ttcgttacct ttcataagta tcttagccat
    49141 taaaattccc ccttaaatat taattaaatt aatctctttc tactgttata actacatctg
    49201 gacacatagt tgcacaactt gcacatccta tgcatttttc catttcaaaa acagttgctg
    49261 ggttataccc ttttttgttt attacatttg agtctaattg tatgattttt actggacatg
    49321 cttcaacaca caatccacaa cctttacaac gttcttgatt aaaagatact tttcctttag
    49381 ccatttacct aagcctcctt aaactttcta tatatttgag ctcaaactac atccagtctt
    49441 ctctcatata taattttata ggaaaaattt ctccttctaa atcttttggt aactgttcaa
    49501 caagattttc taaacatgca acatatctta tcggtatatt acatttttca gaaacttctt
    49561 ttgcaacttt ctgacctctt aaaacatcat caatagtagt aaacctaata agatgagtat
    49621 tattaattag acctgttacc tttaatttag aagatttttc tatttctttt atatattgga
    49681 taacttcttc agaagtttga gttttctccc tatttgcatt tattacaaaa agcatatcat
    49741 aatcgccttc ttttaacaaa tgactaaatc ttcctataac cctagcacct acattatctc
    49801 cacctaaatc tataacagaa ttgtatgaat ggtctaccat aggagacatt acctctgctg
    49861 atactgctgg taaatctaat gttggagcat taattgagct atctattggt tgtataccta
    49921 aggatttcat taactctttc ttttctctag ttctaaagta tacatttacc acatctaaat
    49981 cggctatagc aactttgcca gaaaccatat ctcttaactt aacaacatag ttcatcgcaa
    50041 attcactttt accacttcca tagtgaccag ttatgattct tattctttta tcattagtta
    50101 tcataaactt gagcctcttc ttcaccagtt aaaactctaa gtccaccttg agctaatgca
    50161 atcatttcat cttcacctgg ataaactttt acatctgcta taaatttaac tctatctgca
    50221 atcatttctg taaacatttt tgaatatgcg attccaccag ttaataatat tgcttttaca
    50281 tctcccttaa gaactgcagc actagctcct atttctttag agatttgata tgccatagct
    50341 tcatatacta atttagcttt ttcatcgcca gcttcaattc tttcttcaac ttctctagca
    50401 tcattagtgt ttaagtatgc aactaatccg ccattacctt ttattttctt tttaatttca
    50461 tcttgagtat attttccact aaagcacatt tttactaatg cacctactgg tagtccacca
    50521 cttctttctg gagagaaagg tccttctcca tctaatgcgt ttgcaacatc tactatttta
    50581 ccatttttat gagctccaac agaaactcct ccacccatgt gtgcaactat aagatttata
    50641 tcttcatatt tcttgtttat ttctctagca tatcttcttg ctattgcctt ttgatttaaa
    50701 gcatgtacta cacttgctct acttatttca ggcataccag aaattctagc aacatcttct
    50761 aattcatcta caacaacagg gtctactatg tatgaaggaa catttacttc ttcacctatt
    50821 tgttttgcta ttattccacc tagatttgaa gcgtgttctc ctaaaactcc cacttttaaa
    50881 tcttcaatca tagcagcact tactgaataa gtaccacctt ttataggttt aagaagtcct
    50941 cctctaccta ctacagcatc taattcagat gtttttactc caccttcttt tagagcttct
    51001 tctattactt gtttacgaaa ttcaaattgg tcagacacct tctcatattt tcctatttct
    51061 tctgaagaat gtcttaaagt tttttcaaat actaaatcct cattatcaaa tacagctatt
    51121 ttagttgatg tcgaaccagg atttattgtt aagattttaa atattttgct catttgccta
    51181 tttccccctt aaaattatgc ctttgctgcc attaaaacac ctaaagctat tgagtttagt
    51241 ttagtttctt cactgtctgc tctagaagtt aatattattg gtgctttagc cccaactata
    51301 actcctgcat tttttgattt tgagaagaat actaaagctt tatataatat gttaccacct
    51361 tcaatatctg gggctaataa tatatcagct cttcctgcta caggatgatt tataccttta
    51421 tgtttagctg cttctaaaga tactgcatta tcaattgcaa aaggtccacc aaccatacaa
    51481 cctttgattt ctcctctttc atacatttct tctagttctt tagcttcaac tgtatctttc
    51541 atttttggat ttactttttc ttttgcgcat attgcagcaa cttttggttc acttatatct
    51601 aatgaatgtg ctactgtgca agcattttct atgatttgct ttttagtatt tgtatcagga
    51661 gctaagttca tagctgcgtc agttacgaaa aataatctat catatccctc tacatcaaat
    51721 actgctacgt gacttaatac atttccagtt ctaagaccta cttctttatt taaaactgct
    51781 tttagtatta ttgatgtgtc tactaagcct ttcattacca tgtcggcttt tccttgtgaa
    51841 actaattcaa cagattttag agatgcttct gctaaatctt ttatatctat cagttcataa
    51901 ttttcgatat ccatgtctat gctttttgca atttctttag tcttttctat atctcctact
    51961 aaaatggcat ttgctatttt ttcttttcta gccatttcaa ctgccattaa aacttcttta
    52021 tcttggcaac atgctactga tatagtttta ggtcctcttt cttttgcaaa cttaattact
    52081 tcttcaaaac ttctcatgca tttccacctc atcttgaatt ttttgaaata gaacttttta
    52141 tatctcaatt aaattataac tcgttcagca acgttttcct agagataatt gaaatattta
    52201 attcaaaata tttatttaaa tctatttatc agtctttttt catatatcta gcgcttttta
    52261 gatttaacaa atatctcatt gtccttattt tataatataa ctaaaataaa caagatgcaa
    52321 caaaaacata aaattaacaa acttaatttt ataggttttt ttgtcgcatc ttgtaacaac
    52381 taaatattcg aaatatttgt tcattccact tcaacaatat taggttctat atttattttt
    52441 ttaaattgat atgttgtttc atattttatt ttatatttac tatcttcctc agggccttgt
    52501 gataaatcaa tatataatga aatatctttt ttatttaact tactcaaatc ctccgttgac
    52561 tctacaacaa cttttatatc tacatcagaa attacatttg gattatctat atttgttggg
    52621 atatttctta attcaatatc tcccgcatta tataaaaatt ctgcactcaa ttgttttgta
    52681 tcatttaatt taattgttat agagctatcc tcaagagtta taccctctgg aatttctaag
    52741 ctaacttctt tttcttcacc attagccaaa tcagctaagt caataggttt tgtcttaata
    52801 taacttattt tgtctatatc ttctttcttt ccttttattg taacttgttc cttacttaat
    52861 ttatagtttt tcagtacatc attatcttta ttatcattta gacttactct tattgggaca
    52921 attttttcct tcaatagttc tatctttgca gtcacaaagg atgaacttaa tgttactcct
    52981 tcaaccttag ttccatcact atttaatggt attaattgca attttttaga aaaatcatct
    53041 gtctcattac caacatctag attagctctt acacttttga cttctttaac tagagttctt
    53101 ggacctgata catcgacaaa ttccttacta agttcaattt tatttatatt tctttttgaa
    53161 tttccactta cttctacctt tatatctctt ttttctttta tgtttttttc aagatttact
    53221 actaaaacat catgcttaaa ttctagagta acaccttgag gaatatttgc ttttaaatat
    53281 acttccttct gtccttgtat tgggtcttca atggttccat atacatgtat atcttctttc
    53341 ttaacacttt gtacctttga taaactacct tttatatata catctgctgt taatttttcg
    53401 tctggatata taacaagatt tttatccttt aaatcactca tattacttat agatacaggt
    53461 atatcttcaa accctttagt ttcttcaggg tcaactacag ccataacata catccataat
    53521 gcaattgcac ttaaaaatga tattattttt attttggtat tattttttag tctatttatc
    53581 atttaaatat accacctttg aaaaaacttc ttgtttctgt atttgttttt aaattactac
    53641 gtaatatatt catcattctt tctctagaaa tatctctata taacttacct gctttagcaa
    53701 ttgatacgcc acctgtttcc tctgatacaa tcagagttat acagtcagac acctcactta
    53761 cccctattcc tgctctatgt ctagtaccca aatctttact taaatcctta ctttccgtca
    53821 atggcaaaaa acatgcagct gcttttacct tagaatctct aattacaaca gctccatcgt
    53881 gtaatggtgt atttggtata aatatattta ttaatagttg cctagaaatt tcagcatcaa
    53941 taatagttcc tgtatttatt atatcactta ttctagtttc tctctccatt atgataagag
    54001 ctcctatttt ttgtctagaa agtgaatata aagcttctac aatttcttct atatttctat
    54061 tgagagtttc ttcagaagta tttacattct ttccaaataa attaaacttt gctcttccta
    54121 tatgttcaag tcctgctcta aattctggtt gaaaaattat aagagcagct ataactccat
    54181 aatctaaagc tttaagagat atccaataaa cggtatgcaa tttaaaggtg ttactaagtt
    54241 gagttgctaa taaaagaaat attatacctt taaacacttg ttctgctctt gtatctttta
    54301 taaacataaa tattttgtaa aaaatatacg ctactataga tatgtcaatt aaatcatata
    54361 tactcattct taatattata ttaaaaaatc catttaaaaa agaatttata tctaacacag
    54421 ttttatcctc ctgtttgata acttcttaat tatttacact aagtattata ctatataaat
    54481 ctaactctat acaaactatt taacttttat gtaaataatt ctagttttat atttggagat
    54541 tgttaaataa tctctaaaca cattaaaaat atcaacttaa taaatacata tttcttatta
    54601 aagttagttt ttactcaaat aactcaaacc atcaaggcgc gaatacaaaa tagtactcgc
    54661 gccttaatgc agttttatgt tctaaaatat cttaatatat ctttgtttaa tatatattaa
    54721 ttattataaa ttctataatc cacttattaa ctataaacaa atacaaaatc taaatattac
    54781 ttatcatcaa tattattcca ttagattcat ttttatatta aagtaataac ttatttcata
    54841 tctagattag ataaatttat tttaatatct tactataaac tatcattaaa acttattatg
    54901 tataactaga tataatctcc tacagtgaaa ataatacaca atacctaaag ttatatatcc
    54961 atttcacagt ataataattt acttagtata acttataaat attacattaa attgtcaatt
    55021 cactatagtc tctaattttt tataatttct tatacttatt gtttagacaa aaatatgctc
    55081 ataaatctct ttataaataa tttcataagt tatttcaata tataaatacc ataaagtata
    55141 caatataatg tatataactc ttatctaatt agttatattt aactgatgcc ttcataaaca
    55201 tcttgtagac tattatacat taccctccgt atgtttacaa tattaatgaa tatactgtaa
    55261 ctctattaga atatactgta atttttacat agtttaaagt ttataaataa aaagacacag
    55321 gtaatataca tgtttcctgt gtctttttaa acaatataaa agtttactat aatttatagt
    55381 aaacttttct taatgagcgc acagggattc gaaccccgga cacacgcctt agaagggcgt
    55441 tgctctatcc agctgagcta tgcacccaag ttattatgga gcgggaaacg agattcgaac
    55501 tcgcgacttc aaccttggca aggttgcgct ctaccactga actattcccg cttatttaat
    55561 ttggcgacct ggaaggggct cgaaccctcg acctccagcg tgacaggctg gcattctaac
    55621 caactgaact accaggccgc gaatggtggg accaacaggg ctcgaacctg tgaccccctg
    55681 cttgtaaggc aggtgctctc ccagctgagc tatggtccca tttttggagc gggtgaaggg
    55741 gatcgaaccc tcacagctgg cttggaaggc cagaactcta ccattgagct acacccgcat
    55801 atttaattga attggtgact cgtaggggaa ttgaacccct gttaccgccg tgaaagggcg
    55861 gtgtcttaac ctcttgacca acgagccgtt ttaatggttg cggaggcagg acttgaacct
    55921 acgaccttcg ggttatgagc ccgacgagct gccaactgct ccaccccgcg atattgtttt
    55981 ataagtgccg aagaccggaa tcgaaccggt acgagaggta agtcccgcag gattttaagt
    56041 cctgtgcgtc tgccagttcc gccacttcgg cttttttggc tccaagggtg gggctcgaac
    56101 ccacagccta ccggttaaca gccggttgct ccaccgttga gctaccttgg aacatttaac
    56161 gtggctacgt cctactctcc caggcagttt cccaccaagt accatcagcg ctagagagct
    56221 taacttctgt gttcggaatg ggaacaggtg tatcctctct gctattgtaa ccacataatc
    56281 tttatgctta atatttctat taagttttta ataagtttat agaacctagc aatactagtt
    56341 tctttagagt ta
//
LOCUS       DAMJYN010000013        55446 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.013, whole genome shotgun sequence.
ACCESSION   DAMJYN010000013 DAMJYN010000000
VERSION     DAMJYN010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 55446)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55446)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55446
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.013"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            27..101
                     /locus_tag="PC466_000910"
     tRNA            27..101
                     /locus_tag="PC466_000910"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:59..61,aa:Thr,seq:tgt)
     gene            116..200
                     /locus_tag="PC466_000911"
     tRNA            116..200
                     /locus_tag="PC466_000911"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:150..152,aa:Tyr,seq:gta)
     gene            210..293
                     /locus_tag="PC466_000912"
     tRNA            210..293
                     /locus_tag="PC466_000912"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:244..246,aa:Leu,seq:tag)
     gene            317..391
                     /locus_tag="PC466_000913"
     tRNA            317..391
                     /locus_tag="PC466_000913"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:349..351,aa:Gly,seq:gcc)
     gene            416..492
                     /locus_tag="PC466_000914"
     tRNA            416..492
                     /locus_tag="PC466_000914"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:450..452,aa:Arg,seq:tct)
     gene            502..577
                     /locus_tag="PC466_000915"
     tRNA            502..577
                     /locus_tag="PC466_000915"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:535..537,aa:Gln,seq:ttg)
     gene            586..661
                     /locus_tag="PC466_000916"
     tRNA            586..661
                     /locus_tag="PC466_000916"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:619..621,aa:Lys,seq:ttt)
     gene            664..752
                     /locus_tag="PC466_000917"
     tRNA            664..752
                     /locus_tag="PC466_000917"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:698..700,aa:Ser,seq:tga)
     gene            756..831
                     /locus_tag="PC466_000918"
     tRNA            756..831
                     /locus_tag="PC466_000918"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:789..791,aa:Phe,seq:gaa)
     gene            838..911
                     /locus_tag="PC466_000919"
     tRNA            838..911
                     /locus_tag="PC466_000919"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:872..874,aa:Met,seq:cat)
     gene            926..1002
                     /locus_tag="PC466_000920"
     tRNA            926..1002
                     /locus_tag="PC466_000920"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:960..962,aa:Ile,seq:cat)
     gene            1020..1096
                     /locus_tag="PC466_000921"
     tRNA            1020..1096
                     /locus_tag="PC466_000921"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1054..1056,aa:His,seq:gtg)
     gene            1105..1180
                     /locus_tag="PC466_000922"
     tRNA            1105..1180
                     /locus_tag="PC466_000922"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1138..1140,aa:Lys,seq:ttt)
     gene            1188..1261
                     /locus_tag="PC466_000923"
     tRNA            1188..1261
                     /locus_tag="PC466_000923"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1220..1222,aa:Cys,seq:gca)
     gene            1269..1345
                     /locus_tag="PC466_000924"
     tRNA            1269..1345
                     /locus_tag="PC466_000924"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1303..1305,aa:Arg,seq:acg)
     gene            1358..1433
                     /locus_tag="PC466_000925"
     tRNA            1358..1433
                     /locus_tag="PC466_000925"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1391..1393,aa:Val,seq:tac)
     gene            1509..1922
                     /locus_tag="PC466_000926"
     CDS             1509..1922
                     /locus_tag="PC466_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768322.1"
                     /translation="MYIVIGNEIVDSEELKIIIDENSKFKVEKDLSKSTKREDVIAYQ
                     LSIDLNYLDSLINEQCNLSSLSDEEKFDEYMTLSDELALDLEELMPKYTIINARAYKL
                     DEVDGIVKIILAVAYADLGHLKLSDVVKRLSRQVD"
     gene            2231..5662
                     /locus_tag="PC466_000927"
     CDS             2231..5662
                     /locus_tag="PC466_000927"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HDF2768323.1"
                     /translation="MLKKFNKILVANRGEIAIRIFRACSELGIKSVGIYSKEDKYGLF
                     RTKADESYLIGEGKGPIDAYLDMDGIIDLAKRKKVDAIHPGYGFLAENAEFARKCEEN
                     GITFIGPSSKVMNMMGDKINSKKIAKEVNVQTIPGVEKAIRSTEEAKEVANKIGYPVM
                     IKASNGGGGRGMRIVHREEDLELEYETACSESRKAFGEDIIFIEKYIADPKHIEVQIL
                     GDNYGNIVHLYERDCSVQRRHQKIIEYAPAFSLDDKVRKEICEDAVKLSKHVGYSNAG
                     TLEFLVDANGGHYFIEMNTRVQVEHTVTEMVTGIDIVQSQILIAQGYSLDSEEINIKS
                     QDDVEIRGYSIQCRITTEDPKNKFMPDTGKIQVYRTGSGFGIRLDGGNGFTGANISPH
                     YDSLLVKTISWDRTFQGAINKTIRSIKELRVRGVKTNVGFLVNVLNNPIFSNGKCSTK
                     FIDENPDLFEITESKDRGTKLLQFIGDVIVNDNACKEKPLFDALHDPRMDKDGSKSEG
                     SKILFDKLGKSAYIEKIKNDKKLLLTDTTMRDAHQSLLATRIRTYDLLKAAKPTEKYQ
                     KDLFSLEMWGGATYDVAYRFLKESPWRRLQKLREEIPSIMFQMLLRASNGVGYKNYPD
                     NVIEEFTKESARQGIDVFRIFDSLNWVENMKPSINTALETGKIVEATMCYTGDILDKT
                     KTKYNLEYYIKMAQELESLGADIIAIKDMSGLLKPYSAYTLVKELKKNVKAPIHLHTH
                     DTSGNGVATCLMASEAGVDIIDAALESMAGLTSQPSLNAIVEALKNTERDTGIDLFGY
                     DELGKYYKDLRKVYNKFESDLTNSCAEIYNFEIPGGQYTNLKPQADSLGLVNRFDEVK
                     EKYKEANEVVGDIIKVTPSSKVVGDLAIFMTKNKLDKDNIIEEGKNLSFPDSVVDYCK
                     GMIGQPEGGIPKDLQEVVLKGEEAITVRPGSLLPAEDFDEIAKYLNEKYDINANIRNV
                     ISYALYPKVYEDYIKHLQHYNDISKLESDVFFYGLNKNEECEVEIEEGKVLTIRLVEI
                     GEVKENGFRTIGFELNGMVREVEIKDKNFSGKINNVEKADMNDPLQIGASIPGKVIKI
                     MVKEEDEVKANQPLIVIEAMKMETIIVAKTDGVIKSIKVKEDDMVEDKQLLMIMK"
     gene            5904..7832
                     /locus_tag="PC466_000928"
     CDS             5904..7832
                     /locus_tag="PC466_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HDF2768324.1"
                     /translation="MKVYDSKMLRNVAVLGHSGCGKTNLIETIAYTANTNKIPKLTDK
                     VNMTYSMGLIPIEYNDYKFNLLDTPGYFDFSGDVVSSLRASDAAIIVIDATAPIQVGT
                     EKSLELTESIPKIMFINKIDNEKARYKDAIAMLREKYNNKIVPMISPIYKDKNFVKLH
                     NVFENIDDLEGEFKEQAMSVKEALMELIAETDDQILDKYFNGEELTTEEIQKGIIIGI
                     QRGDIIPVICGSTINNIGTKEILDTISSYLEPIFTEESKPFRGLVFKTMVDPFVGKMS
                     YIKITEGVLSKDKDVFNINKNVKEKIANIYTLRNSELVEIEKAKAGDIVVITKVNSLK
                     TGDTISADKDAEALEKIDFPKPQIYYAVTPKNKGDEEKVASVLNKLVEEDPTLHWYRN
                     TETKQALLGGQGELHIKTIKNKMKDKFGVDVELNDLKVPYRETIKGTADVQGKHKKQS
                     GGHGQYGDVKIRFERCESDFEFTEEIFGGSVPKQYIPAVEKGLKDSMQKGILAGYPVT
                     NIKATLYDGSYHDVDSSEMAFKMAASAAFKKGMEEAHPILLEPIMKLKITVPEEYMGD
                     VMGDINKRRGKIFGMEPDDKGKQIIFAEAPQAETFKYAIDLRAMTQGRGYFEMELERY
                     GEVPSQFAEKIIGLATAK"
     gene            8285..8749
                     /locus_tag="PC466_000929"
     CDS             8285..8749
                     /locus_tag="PC466_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HDF2768325.1"
                     /translation="MATMTDIIEKFIKDLMEEDNSIQIQRNELANLFSCAPSQINYVL
                     TTRFTIDRGYYIESKKGGGGYVQIEKIRKSKDGHIRELLNEKIGSQISYKKAKELLEG
                     LKESDLINERELKLILYAIDDKSLCMPIYELKEKVRSNILKNIIIGLFSIEE"
     gene            8756..9250
                     /locus_tag="PC466_000930"
     CDS             8756..9250
                     /locus_tag="PC466_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UvrB/UvrC motif-containing protein"
                     /protein_id="HDF2768326.1"
                     /translation="MLCQKCNKNKASVYYNKIVNGEKTEMYLCSECAKENTEMNFNLD
                     MPFSMMDIFSNLGFQPKKELEEKLVCPKCNTTYSEFKNNGRFGCSECYNAFSSQVNPM
                     LQNIHGHIEHTGKAPKKSFYKISVENEIKELKEDLDRAIKNEEYELAAQFRDKIKYLK
                     GSID"
     gene            9266..10291
                     /locus_tag="PC466_000931"
     CDS             9266..10291
                     /locus_tag="PC466_000931"
                     /EC_number="2.7.14.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein arginine kinase"
                     /protein_id="HDF2768327.1"
                     /translation="MKENIVMKSRVRLARNLNNYPFPNKLDKECAMEIIEKVKNAFIN
                     SNLEQKEEFDFYKIEDLDQSKKMLMVEEHIISPDLAENDKSAVIVKKDKTISIMINEE
                     DHIRIQTICDDLNLEYAYSVANEIDDLLESSLEYAFNTKLGYLTSCPTNTGTGMRASV
                     MMHLPALSQLGYMDELYKISSQIGIAIRGIYGERTEALGNIYQISNQLTLGRTESNII
                     ENVSGLTKDAISKEIKAREILQKKLGIKLEDKIFRSIGTLENSRVMSSAEAMSHLSNI
                     KMGIEMNYIDKLDLRAIEQLMIGIQPAHQSIMYKSDDVENRDINRATYIRETLEKLRG
                     GMNCELQ"
     gene            10278..12725
                     /locus_tag="PC466_000932"
     CDS             10278..12725
                     /locus_tag="PC466_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HDF2768328.1"
                     /translation="MNFNRFTQRAKKAIDLAFESAKSLGHNIVGSEHILLGLLREEEG
                     IAAKVLSKVGFTEAYLEGKIVDMEGKGEEISEDIVLSPRSKQILELSGMFANKLKTNY
                     IGTEHILLAIIQEGEGIANKILNYAGVNDRTLAQLTIDMMGISDKNQYKAENSYTGNQ
                     NQAESKVLDKYGRNLTLYAKQNKIDPVIGREKEIQRVIQILSRRTKNNPVLIGDPGVG
                     KTAIAEGLATNIALGNVPETLKNKTLYSLEMGSLLAGAKYRGEFEERIKEVVDEVVKN
                     GNIILFIDEMHTIIGAGSTGEGSIDASNILKPALARGEIQVIGATTIDEYRKHVEKDS
                     ALERRFQPVMVDEPTKEDSIKILEGLRDKYEAHHKVKITDDAIKAAVELSTRYISDRY
                     LPDKAIDLIDEAASKVRLKENTPPSEIKKLELEIENIDKEKEEAVRCQDFEKAAKIRD
                     EQGLLKKQLEDVRERWNKSSKHSDLVDGEVIAEVVGLWTGIPVNKILEEEADRLLRLE
                     EILHNRVIGQEQAVKSISKAIRRSRAGLKDPNRPIGSFLFLGPTGVGKTELSKALAEV
                     QFGDENQIIRIDMSEYMEKHAVSRMIGSPPGYVGHDEGGQLTEKVRRNPYSVILFDEI
                     EKAHPDVFNILLQILDDGRLTDSKGRTVDFKNTIVIMTSNVGASTIGRQKTLGFSIAK
                     GDEEEKSQYEKMKENIMGELKQRFRPEFLNRIDDIIVFHSLNENHISKIVLLMAAKLQ
                     ERLKEMDIKLEMSDEAVKLISKSGFDLEYGARPLKRALQKELEDELSEAILKGNVKKG
                     SNVVAKVKDEKIVFETK"
     gene            12905..14278
                     /gene="radA"
                     /locus_tag="PC466_000933"
     CDS             12905..14278
                     /gene="radA"
                     /locus_tag="PC466_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HDF2768329.1"
                     /translation="MAKIKTKYVCQSCGYETAKWLGKCPECTKWNTFVEEIDQKSTKK
                     EVFIIDKSSSKPVSINSIESKEEERFTTDINELDRVLGGGIVKGSLVLVGGDPGIGKS
                     TLLIQVSSNVANLGKTVLYITGEESESQIKMRAKRLGINSENLYIFAENNLSIIESYL
                     ESVNPELIILDSIQTVFSPEISSAPGTVSQIKEGTSKFMKISKKMGISTFIVGHVTKE
                     GSLAGPKLLEHMVDTVLYFEGERYNTYRLVRAVKNRFGSTNELGVFEMRDLGLVELDN
                     PSKILISEKPKDVAGSVIISTVEGTRPMLLELQALVSPTSFGIPKRTSTGVDYNRVGM
                     LLAVLEKRVGLQIQNQDVYINIVGGIKINEPSIDLGIAISVASSFRNIPIDENIAVTG
                     EVGLTGEVRAVSFIEKRIAECKKLGFKKIVVPRSNYDVVKETKGIEIWPVDNLRQAIN
                     IVLGRNQ"
     gene            14281..15351
                     /gene="disA"
                     /locus_tag="PC466_000934"
     CDS             14281..15351
                     /gene="disA"
                     /locus_tag="PC466_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA integrity scanning protein DisA"
                     /protein_id="HDF2768330.1"
                     /translation="MENFLDNKNMLYALKMISPGTPLRLGLNNVLRAKTGGLIVIATN
                     EDVMKIVDGGFAINAEYSPSYLYELAKMDGAIVLSGDVKKILFANAQLIPDYFIETSE
                     TGTRHRTAERVAKQTGAIVIGISQRRNVITVYRGNEKYVVEDISKIFTKANQAIQTLE
                     KYKTVLDQAVTNLNALEFNDLVTIYDVALVMQKMEMVMRVTSIIEKYVIELGDEGTLV
                     SMQLEELMGTTRIDQKLIFKDYNKENTEIKELMKKVKNLNSEELIELVNMAKLLGYSG
                     FSESMDMPIKTRGYRILSKIHRLPTAIIENLVNYFENFQQILDASIEELDEVEGIGEI
                     RATYIKNGLIKMKQLVLLDRHI"
     gene            15440..16534
                     /locus_tag="PC466_000935"
     CDS             15440..16534
                     /locus_tag="PC466_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HDF2768331.1"
                     /translation="MIRKVTRILFILLGFTIGITTYLTLMKDFEILTFGKETYGYIAA
                     VVAGIIIAILGYLIEPWVVNKVKEIAKIVDKELSKYPQTDILLGSMGLIVGFVIAYLL
                     SGLVNRIPIVGGILSLLLYLFLGYLGMKVALKSKNDLFNIGKLGRLANPIKDKDKDKE
                     NKKEVKAIPPKVLDTSVIIDGRIADICKTGFIEGKLIIPAFVLEELRHIADSSDDLKR
                     VRGRRGLDILNIIQKELNIEVEISERDFDDIAEVDSKLLKLAQVLNGKVVTNDYNLNK
                     VAQFQGVEVLNINELANAIKPVAIPGEDMVVQVVKEGKEAQQGVAYLDDGTMIVVDGG
                     RKYMNETIKVLVTSVLQTPAGRMIFAKPKN"
     gene            16663..18840
                     /locus_tag="PC466_000936"
     CDS             16663..18840
                     /locus_tag="PC466_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768332.1"
                     /translation="MRKKIISFLATFIIILTSASQYSFADDMSTRGKVIFIDMNRTSM
                     SNMLRIKSLREELDNRGYIGLMNIRGDKGSDDRRSYASMGAGGRANVANEEDINFESS
                     SKDRNIVFESATGKSAKGINNLTINKSINENLNFGEYGSVLGSLGQSLSENGLKASVL
                     GNSDIIENGQLIKNRNLCLTAMDEYGRIPNGNVDTINKKDLSMPYGISTDYDKLIVET
                     KEAYKNNDVVFVELGDTYRLDLYKPNLNEKTYESVKDNIEKNIDVYLKNIFSMVEEND
                     TVYIASAFPSDLDYKNKRRLSPIIKLNGEGKGILSSSTTRREGIVTNLDVGVEILDNF
                     NIKNQNMVGRKYELINRDDNKEFLMDEYQKIVSISSIRSTILNGFVSIVFLSWIVAMI
                     AILFRKHISKNYKETTFFILKELLKIGIVMPLSFMITPIMNFKTPLAISLGIIIITLT
                     IYLISKVLIKNDLKNMLFFTGLTIVIMVIDAGFGSYLMKSNVMSYDCIIGARYYGVGN
                     EYQGVAIGSAIFTFAILLTYKNIPKWSIIVFSLVILITSASPIMGANVGSAISECVAF
                     LLFILLIYNVKIDFKKIVLLGIAVLFVLGVFVAIDMILGSNSHLGMFVKEIYFNGPGE
                     IIQTFSRKIEMNLKLAQTSAWVNILLTGIGVILVLMINQIRYFKQLMDEYPIVFKGFI
                     ASIAGCLVTLLVNDSGIVSSATAFIYVIVPMITLSINLTALKE"
     gene            complement(19026..19871)
                     /locus_tag="PC466_000937"
     CDS             complement(19026..19871)
                     /locus_tag="PC466_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2768333.1"
                     /translation="MNRNNFSHEIIEPIDNLDVNFKLFDDSGSYVANHWHNSLEIIYI
                     TSGDLQINMEGYTYNLKANECMFINSGIIHSTRCTYQDTSILLQVPLSFLNKYIPDFK
                     NCYFDFKVNANDNNYKKNSGKVKLILENMREIKLSSPPAANLLFTSLLFELLFELYTN
                     FKISVGNKNMKKTVLDLSKFEPVLEYTKINYKMPISINKIAKVAHLQPEYFCRKFKQY
                     MGQTYLEYLNDVRISHIYKDLINTNDTLCSILEAHGFTNTKLFYRIFKEKFKCTPKHI
                     RKKST"
     gene            20088..21254
                     /locus_tag="PC466_000938"
     CDS             20088..21254
                     /locus_tag="PC466_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulase family glycosylhydrolase"
                     /protein_id="HDF2768334.1"
                     /translation="MYIKGVNLGGWLVLEKWMTSSLFEGTEAEDEYYLPRQLSREAYE
                     SRIKTHRSEYITERDFATIKSMGFNSVRIPVPYFIFGDCEPFIGCVKELDKAFAWADK
                     YGLSILIDLHTVPGSQNGFDNGGISGICSWSQNPEYVAFTLNVLERLAKRYGMRHELY
                     GIQILNEPITERMWNIMNVPNRFKAVDKEMARGSKPNSLEFLRDFYIKAYKVMRPYMR
                     EENVIVFHDAFELKAWKDFMREEEFKNIVLDTHQYLMLAESDGCEQSIDSYLKYIREN
                     YAKDILQMQKYFPVICGEWSLFNSYACGIDTNGGQSPLNGIESNIDKLSKDDKRELYR
                     KIAKAQLDAWRNGSGHYYWNYKLLLDTVNEEGWIGWDSWDLGKCVAQEWYPIEY"
     gene            21276..22922
                     /locus_tag="PC466_000939"
     CDS             21276..22922
                     /locus_tag="PC466_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HDF2768335.1"
                     /translation="MIKNPILPGFNPDPCICRKGDDYYLVVSSFEWFPGIPVYHSKDL
                     KNWELYTHILTDETKIDLKKLPSSKGIWAPCLTYCEEEDLFYIVYGIMNSMNARYFDV
                     DNYLITSKDIKGEWSEPVYIHSSGFDASILHDDDGKKWIASLDWETREGYEKPGVICL
                     VEYCTKKKEIVGYPKRIWSGGTDRGCIEAPHITKRGDYYYIMCAEGGTGYGHSVTMGR
                     AKNIWRPYEKDSMNPIVTSIPGDFYERHDPDHLKPKYYNPESKLQKSGHGSYIETTSG
                     EVYLVHLTSRPFVPELRCTLGRETAIQKMKWTKDNWLRMEDESNLAKEYVSESKLEEH
                     LVSSIPSFDDFDSNVLGLQYYAPRISPLSFADVKSRPGYVRIRGQESRTSLNKVSILA
                     RKLTSVYARITTKMEFYPEVHQHSAGLIMYYDNMNYINLRKYYSETLGQSALSIIHLE
                     NGEKTEFLNTRIPIKDIPIYLRLYIQGRKSYFEWSYDEKNYQRIGKVFDTTKFSDEYC
                     KYGEFTGTFIGLTCADRVKHKHYADFDFFEYIADESKDVD"
     gene            23019..24392
                     /locus_tag="PC466_000940"
     CDS             23019..24392
                     /locus_tag="PC466_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2768336.1"
                     /translation="MNTEVNVKATTIRYEKISFFERISYGCGDLGCNIIYSAMSAFLL
                     FYYTNYADVSAAAVGSIMLVSRILDGFSDLTMGIIVDRTKSKYGKARPWILRMAIPFA
                     IAAVLLFSVPSNLGITSKLIYIFITYNLVSTVIYTAINVPYATLNSLITQNQYERGVL
                     SIFRMILATCGTLLINGLTLPLVEYFGNNLSAWTKTFFVFGIASIMVFFITFTGTKER
                     VKAVKQDRNEVIPFKIGIKSLFRNKYWIQITLCLVCIFIVFAINGGSSVYYAKFILGD
                     EKLFGPINMVSNISQIIAMFMVAPFIKKFGKRNVLIVGSIILISSNVMFIIVGQNYIG
                     VIFASAIKGIGSAGIASTMFAIVSDTIEYGEWKTGYRTEGLINSASSFGFKVGNGLGS
                     AILGAVLSIGGYVGTSATQSDLAIVSIKVCFIYLPIFITILQIIIMFFYKLDKEYSTI
                     LNELNTK"
     gene            24837..25790
                     /locus_tag="PC466_000941"
     CDS             24837..25790
                     /locus_tag="PC466_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HDF2768337.1"
                     /translation="MKKIGDLRLMMKCCSLYYEDNLNQQEIANQLGISRPTISRILKE
                     AFEQGIVKIQIVDVLKNDYQKIERSLERKYKLKEVIVVDDKQDALTQKQELARAVSEY
                     LTRVVKENDIIGVSIGTTLKEIPRYVEKSNCKNVTFIPLLGGIGDNEIDIHANQIAVS
                     LARAFGGDFKLLHAPAVMSDLSTKEKLCKDEKIKEVLDLIDKTTIAIVGIGNPMSLNS
                     TIMASGYMNEADIEDLKKYNSIGAICLQAFDKEGKTSILEFNQRVLGVKLEDLKKIKR
                     TIGVASGDEKIEAIKASLKAKFINSLAINHSLALKLLEDCD"
     gene            25828..26790
                     /locus_tag="PC466_000942"
     CDS             25828..26790
                     /locus_tag="PC466_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HDF2768338.1"
                     /translation="MSISKETLLEMYKRMNQARKFEEKVSWFFARGMVHGTTHLSVGQ
                     EASSVAAVMALEKGDLVSLTHRGHSQFIGMGIDLNKMMAELMGKETGFCKGKGGSMHI
                     ADIESGNLGANGVVGGGLTIAPGAALTQQYKKTGKIVLCSFGDGASNEGTFHEGINLS
                     SIWKLPIIFYCENNLYGMSTSIKRHMNIESIATRAASYGIEGISIDGYNPIEVYETVQ
                     KAAEKCRRGEGPVLIESRTYRWLGHSKSDANVYRTKEEIESWKAKDPIEFLKNYLIEN
                     NLSNEDELDKIQEFAKQSIEDAVEFAQNSPNPKIESLLEDVYAD"
     gene            26815..27801
                     /locus_tag="PC466_000943"
     CDS             26815..27801
                     /locus_tag="PC466_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HDF2768339.1"
                     /translation="MSTRELTYAQAIKEAMSEEMRRDENVIFMGEDIGIYGGAFGVSV
                     GMIDEFGPERVRDTPISEAAIAGAAAGAAATGLRPIMEVMFMDFVTISMDAIVNQAAK
                     MRYMFGGKAQVPMVVRCPGGSGTGSAEQHSQSLEAWFCHVPGVKVVAPSTPADAKGLL
                     KAAIRDNNPVIFVENKLLYRKKGFVPEDDYVIEIGKADIKREGTDVTVITYGRMLQSV
                     EEAAETLSKENINVEIIDLRTLYPLDKETIVKSVCKTGRVLICHEAAKTGGLGGEISA
                     LITESESFDYLDAPVKRICGKDVPIPYNPELEKAVVPRVDEIEEAIKSLIVR"
     gene            27814..28860
                     /locus_tag="PC466_000944"
     CDS             27814..28860
                     /locus_tag="PC466_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxo acid dehydrogenase subunit E2"
                     /protein_id="HDF2768340.1"
                     /translation="MVANKIKATPAARSQARKDNIKLDRLIGSGENGRIHLVDVLNYL
                     KDNKANTTPLARRIAEDLNIDLETIVGTGYSGKIRKCDVEKLTAKETIVSNNTSKYSE
                     KKELKIENENSSMFNTVEGIFEKPNPMRATVAKRMSESYFSAPVFTFNIEVDATELKV
                     LRAKLIDTVKESTGVKLTMTDLIVMAVSKILPNHQALNSAWTDEGIFRYKDVNIAIAV
                     GLDEGLYVPVVKNANKKSLKEIAKESKELAEKVKTGKLMPADQEGNTFTISNVGMYGI
                     TTFTPIINMPSSAILGVGATQDKFVPVNGEAKIKPIMNLSLTSDHRVIDGTVAAKFLK
                     DLKELLENPLSMLV"
     gene            29027..30757
                     /gene="lpdA"
                     /locus_tag="PC466_000945"
     CDS             29027..30757
                     /gene="lpdA"
                     /locus_tag="PC466_000945"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HDF2768341.1"
                     /translation="MSVEVIMPKAGVAMEEGTIVSWLKQEGEEVKIGEPILEITTDKV
                     NMEIESEGEGTLAVIIHKEEGEVLPVFTVIGVIAEKGENQEEVKAKYLSGNVSKEDIV
                     EENQNIEVKEEKINKKECNHDYDVVVIGGGPGGYLSALKAALLGGRVALVEENILGGT
                     CLNRGCIPTKTYIKTAEILEEIDQLSKRGVKVTVDKEQDIKKAIKYKNRVVKKLTAGV
                     GGLLKSRDVDVFNLKASVKEEHKVILSDGKVLDTENIIIATGSKVRILPIKGIESNLI
                     ITSTEALDLETVPEELVIIGGGVIGCEFAEIFNSRGSKVTIVEMEDRVIPRMDKELSE
                     SLKYSLSKKGINVLTKKKVSEFKEEGNNILVCIEGEVPIKADLCLYAIGREANLSGIE
                     DLDIKIDKGSIVVNSKMETSIPSIYAVGDVTGGVMLAHAAFKMGEVAASNALGVNKEV
                     DLGALPSCVYTIPEVASVGITEEDARKKYNVKVGKFNFAGNGRALASGQEQGYVKVVA
                     DAKYGEILGIHMFGCGVAELINHAASFKALEIPTDEASELIFGHPCTSEALMEALADV
                     NGECLHLPKK"
     gene            31175..34123
                     /locus_tag="PC466_000946"
     CDS             31175..34123
                     /locus_tag="PC466_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2768342.1"
                     /translation="MRQRIKNLIENEDKKNPLTDEAISSRLNIRREDVTFLRNELKIE
                     DSRQRRKVVLIKAIKDILKEEKTINKNDITRRLNSIGFTVSRFTVIQYLKEIQDSGDL
                     KLDKESDDKKEEIINNRENKDIAFDKLIGSSGSLSTIIKLAKAAILYPPHGLHTIIMG
                     PTGVGKSELAECMYKFAVESSRFPKNAPFIVFNAADYSENPQLLLSQLFGHVKGAFTG
                     ADENKEGLVSKADGGILFIDEIHRLPHEGQEILFQLIDKGMVRKLGETRLTHKIDVMI
                     ISATSEPIDSHLLNTFKRRIPVTIEIPELVARPLNERFDIINNFFLIEAQRMGANIHI
                     KSDVLKALMLYDCIGNVGQLRSDIQVACARGLLNQLTNKLKEVNISISDVPGYVKQGL
                     IKIRNCRGKIENYVDGDLIIDSNLQGEIEKKNEDIYTFPDEIYKLTERRHIDLLEQGL
                     DFDVINRIIGGELESCIQKYIKQVKKVSISNNLPDISPIVGKYIVELTYEVIKIASQY
                     LSSLEPNLHLCLAVHLKAAFERLKEGKVISNAHLKEIIGNYPLEYSVAEKVAQYLKER
                     YNINLPKEEIGIIAIYFKMSSRRDMSEQKKIGVLLMAHGRVASSVCEVTNKLLGINHA
                     RYLDMPFEKKPEEMIEEATTIIKDIDEGRGVIILVDMGSLSYFGDIISGKTGINIRTI
                     SRFDTLLSIEVIRRAVLPDLTIDEIVDEVKGIEPQVKEKVSKCNNTKVDFRKPIILTL
                     CITGLGGACKIKKILEENIKSITEKVDIEPIGMIEYPSLDLEIKQISNDKNVIAIVGT
                     IDPQIANIPFFSLVDINDKAKLNQINNLIDTNQIGETNKKYELSDLIHKEDIFVDLQV
                     KSKEEVLKYMSKKLREKGYVTKNFYKKVVERDNLFPTELSDEIAIPHTDGIDVIRPAI
                     SIAILKKPIVWSKSKVKIILLLAVDQKCFNPLSTLLSFIETDEFKKIKNIKDRDFIRE
                     MILDGVNENN"
     gene            34101..34565
                     /locus_tag="PC466_000947"
     CDS             34101..34565
                     /locus_tag="PC466_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2768343.1"
                     /translation="MESMKIISSNLIFKNIEVSNNEDALKFLGQRLFDEQYVKESYIQ
                     AVVAREKKYATGLPTEIYGVAIPHTDIVHVNEPGIAIGILNKPVKFIMMGTDDTEIDV
                     KVVFMLAVKEPQEQLQLLEKLMTIFQDKNILNNIVDLSEESVSDLLNSKLKN"
     gene            34678..34980
                     /locus_tag="PC466_000948"
     CDS             34678..34980
                     /locus_tag="PC466_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2768344.1"
                     /translation="MGVTNVTKKILVACGTGVCTSTIAINKLKKALQDIGKLDMVNIT
                     QCKVVEVASKAPDYDLIICTTQVSSSIKTPVINGLPFLTGVGMDKLINDVLEELEL"
     gene            35042..36406
                     /locus_tag="PC466_000949"
     CDS             35042..36406
                     /locus_tag="PC466_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425524.1"
                     /note="with GatAB forms a phosphoenolpyruvate-dependent
                     sugar phosphotransferase transporter for galactitol;
                     subunit IIC forms the translocation channel and contains
                     the substrate binding site; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HDF2768345.1"
                     /translation="MEGLYMEILNFIVGLGAQVMMPIIICIFGLILGTKLGKSLRAGL
                     TVGVGFIGLNTIIALLTDNLGPATQQMVKNLGLSLSIIDVGWPAASAIAFASTVGALI
                     IPIGLVVNIVMLITNTTQTVDVDIWDYWHFAFTGALVAGATQSVMWGVFAAVANMVIV
                     LVMADLTAPGIEEYLGMPGISLPHGFTQAFVPIAIVVNKLLDLIPGINKIEINADTLQ
                     KKFGLFGEPLIMGSVIGVIIGIAAKYDIKGILQLGVTMGAVLILIPKMAALLMEGLLP
                     VSEAAQEFIEKRFKNRGKIYIGLDSAVGIGHPVTLSVALVLVPLTILIAAILPGNKVL
                     PFADLAVIPFALVLIVPITKGNVFRTLIIGIIIITSGLLIATNLAPLFTQMALNASFK
                     MPEGATMISSICDGANPLSWVFVKVMNYKVIGGVVFGVIALGMAIYNRNRIINENKKL
                     SIEE"
     gene            36441..36914
                     /locus_tag="PC466_000950"
     CDS             36441..36914
                     /locus_tag="PC466_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768346.1"
                     /translation="MKKYKYDSKRYLLSVTIPGFFMILILIYALFNNYINFNLNIYSL
                     LIIVCTYGIFNTFISSSNPKKIIIDSKCIHFTSFMTTHKYEIKDIEKIRIREFYNKKI
                     YLKINDGDLFKGRYWIRTNMFNNSIALYSYFIELEECLYPDSLRFRNKKFENKNI"
     gene            37086..37736
                     /locus_tag="PC466_000951"
     CDS             37086..37736
                     /locus_tag="PC466_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HDF2768347.1"
                     /translation="MLLEKLRKEVLQASLDLLNYNLVTLTGGNVSGRDEQTGYIAITP
                     SGMDYRNLTPSDIVIVDVDGNIIDGKWKASVDLSDHLYIYKHREDINSIIHTHSTYSS
                     CFAILNEPIECASTTLANEVGGSVPVAKFSPPTFKKMGKCVIEAIGDKRACLLANHGV
                     IAVGPSVGHALTAAVMLEDSAKVYYLAKSIGTPVLLPDEEIQRARDVFFNVYGQDK"
     gene            37910..38842
                     /locus_tag="PC466_000952"
     CDS             37910..38842
                     /locus_tag="PC466_000952"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HDF2768348.1"
                     /translation="MYYLLNKSTNPYFNLALEEYLFLNDKYNDDIIIIWRNEDSIFIG
                     KNQNPYQEVHHDVIEKGEIPILRRISGGGTVYHDLGNINMSFIQKDRQLHEIDFLEHT
                     KFMQKMLSTLGLDVSITERKDLFLNGKKISGSAQSIKRKNSLYHGTLLYDSDLNKLTK
                     YLNSNKATESNATKSVSSKVTNIKFLLEKDINYFLDYCVEYLKSNIKNIKELELDEED
                     IKSVYNIGEDKYRKIEWTYGKTPKFQVVLPFNNESKINIHVNRWKVSKFFISYDDNVI
                     NMDKLLDLNFFKEEIKESILENYPHYIDLINLIF"
     gene            39116..39829
                     /gene="ispD"
                     /locus_tag="PC466_000953"
     CDS             39116..39829
                     /gene="ispD"
                     /locus_tag="PC466_000953"
                     /EC_number="2.7.7.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HDF2768349.1"
                     /translation="MYSVIIVAAGSGRRMNLDINKQFIKLREKEIIAHTIQVFYENIN
                     IDEIVVCIKKEEEDFFKENIINKYNFKNIKIAYGGKERQDSIYNGLKKLDENCDIVLI
                     HDGARPFVDHRIINESIKVAKEKKAVVVGVPVSDTIKIVSDGTVQETPERNLLWAAQT
                     PQTFEYNLIIDAYEQAYKNNYYGTDDSMLVENIGQSVTMVMGSYENIKITSPEDLNIA
                     EQILNMEKRDEVNSRRRII"
     gene            39826..40311
                     /locus_tag="PC466_000954"
     CDS             39826..40311
                     /locus_tag="PC466_000954"
                     /EC_number="4.6.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 2,4-cyclodiphosphate
                     synthase"
                     /protein_id="HDF2768350.1"
                     /translation="MRIGLGYDVHKLTENRKLIIGGVEIPHDKGLLGHSDADVLIHAI
                     MDSILGALALGDIGKHFPDTDEEYKGADSMKLLEHVYNLITSKGYKIGNIDSTIIAQS
                     PKMAPYIESMRSNISKVLNTDIDNINIKATTEEGLGFTGAKQGIASQSICLLLLTSQN
                     N"
     misc_binding    40406..40614
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            40678..42393
                     /locus_tag="PC466_000955"
     CDS             40678..42393
                     /locus_tag="PC466_000955"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HDF2768351.1"
                     /translation="MKMSKMFMPTLKEIPADAEITSHQLMVRSGMIKKMTSGVYNQLP
                     MGLRVFKKIEQIIREELNKKDCQEILCAALLPSELWKESGRWTAMGEEMFRLKDRTER
                     EYCLGPTHEEAFTDIIRQEITSYKQLPLNLYQIQVKYRDERRPRFGVMRTKTFTMKDA
                     YSFDVDDKGLDKSYQDMFDAYVSIFDRCGLENSPVQADSGAIGGSTSAEFMVKSEVGE
                     DEVVFCSGCDYAANVERAESCNLASQKEEMKELEEVHTPGAATIKELEEFLKTSPDKF
                     AKTLVYEADGKTVVVVVRGDREVNEIKVSNAIGSVIEFALATDDVVRKVTNAEVGFAG
                     PIGINADYVFIDKEIVEQRNIVVGANKTEYHIKNANYGRDFEGIVGDFRNVQEGDQCI
                     VCGKPLEIARGVEVGHIFKLGTKYSESMNANFIDKDGKSKPIVMGCYGIGVERTAAAI
                     IEQHNDEKGIIWPLSVAPYHVVIVPANMKNEEQISIAENIYNDLQAMGVEVLLDDRDE
                     RIGVKFNDSELIGIPMRITVGKNINEGKVEFKLRHKEDKEIIDIEEINEKVKAEFIRN
                     NVRLG"
     gene            42515..43960
                     /locus_tag="PC466_000956"
     CDS             42515..43960
                     /locus_tag="PC466_000956"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HDF2768352.1"
                     /translation="MAKNEKQFVEEITKMEDDFPQWYTDVITKTDLVDYAPVKGFMVV
                     KPYGYALWEKMQEFMDKKFKETGHKNCYFPLLIPESLLNKEAEHVEGFAPEVAWVTHG
                     GNKKLEERLCVRPTSETIICTMYAKWLKSYRELPYLYNQWCSVVRWEKSTRPFLRTSE
                     FLWQEGHTLHETAEEAQEETIQQLEVYKALCEELLAMPVVAGQKSESEKFAGGERTYT
                     IEAMMHDGKALQSGTSHFLGQHFTKAFDITFADREGNLANPYHTSWGASTRLIGGLIM
                     THSDNRGLVLPPRVAPIQVVIVPIAAKKGNVMETVDKIYADLKTKGVAVEVDDRDNYT
                     TGWKFNEWEMKGAPVRVEIGPKDIENNQAMVFRRDTLEKDSMPLEGLADAICDLFDVI
                     HNDMFEKARKHREDNTSIVENMDEFRKALEEKPGFIKTMWCGDAECEAKIKEETGATI
                     RCLPFEQENLGHKCVYCGKEADSMVVMAKAY"
     gene            44400..45881
                     /locus_tag="PC466_000957"
     CDS             44400..45881
                     /locus_tag="PC466_000957"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HDF2768353.1"
                     /translation="MNVRVRFAPSPTGFVHIGSLRTALYNYLFAKKMGGEYILRVEDT
                     DQSRLVEGAIENMLNAMKWAGVNHSEGVILDDSGKVVQKGEYGPYIQSQRLDIYQEYI
                     KQLLDSGKAYYCFCTKERLDEVRDAQRAAGETAKYDGHCKNLSKEEVEANIKAGIPYV
                     IRLRLPENHTIKFTDLVRGDMEFNTNDLDDQVLMKTDGFPTYHFAVVVDDYLMKITHV
                     IRGEEWVSSTPKHVYLYEAFGWEAPVFVHLPNILNKEKKKLSKRQGDVAVEDFKKKGY
                     LPEGLVNYVALVGWSPEDNQELFTMEELEKAFSVERVSKSGGVFDTEKLNWVNQHYIK
                     DGDDAYLTDLAIPFLVEDGFITEEEATNKYDFLKSMISVLKEKLQYVKEITEHASIFF
                     GDKIEVETEEGREFLRLEHIPTLIDALREKIEKTEVLNAEFVQAMLKEIQKEYKIKGK
                     NLFMGSRIILTGQMHGPDLPKVMEVLGKETCLNRIAYVKNNIL"
     gene            46102..46257
                     /locus_tag="PC466_000958"
     CDS             46102..46257
                     /locus_tag="PC466_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768354.1"
                     /translation="MYSNIDDVKKELKELCLEYVTILEKLKDEKMITEETFEKCSSQK
                     KIFLEEQ"
     gene            46402..47799
                     /locus_tag="PC466_000959"
     CDS             46402..47799
                     /locus_tag="PC466_000959"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HDF2768355.1"
                     /translation="MKVYNTLTRTKEEFVPLEEGKVKMYVCGPTVYNYIHIGNARPFI
                     IFDTLRRYLEYRGYDVTYVQNFTDVDDKIINRSHEEGISPEEVAAKYIKEYFVDCDGL
                     GIKRATVHPQVTDNIQQIIEFIKELEDKGYAYAVNGDVYFDTNKFEGYGKLSGQKQED
                     LEAGARIEVNDQKRHPMDFVLWKAKKEGEPGWDSPWGEGRPGWHIECSVMSKRYLGET
                     IDIHAGGQDLTFPHHENEIAQSEARSGKIFSKYWMHNGYININDEKMSKSKGNFFTVR
                     DISKLYDLEIVRFFMLSAHYRNPVNFSDEMLNQAKAGLERLYNTKEKLEFTLSNLVES
                     PLTEKEVELVKELDDFRQKFIDAMDDDVNTADAVSVIFELAKLINSNVDENSSLEFAK
                     KCLDEFNELTGVLNIVNKKKDTVLDKDIEELIQKRTDAKKNKEFQLADDIRQQLLDMG
                     IVLEDTRQGVKWKRI"
     gene            47784..48197
                     /locus_tag="PC466_000960"
     CDS             47784..48197
                     /locus_tag="PC466_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HDF2768356.1"
                     /translation="MEKDIKMEKTELVTMSPLVLAYLGDTVYETYIREYLIRQNTQRK
                     VNDLHKLAIKYVKAKAQATIIHEIEIELTEEESKIYKRGRNQKSNTSPKNADIIDYKH
                     ATGFEALVGYLYLNNEIERLQYIINKGIKIIERDM"
     gene            48304..48399
                     /locus_tag="PC466_000961"
                     /pseudo
     CDS             48304..48399
                     /locus_tag="PC466_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003452247.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase (FAD)"
     gene            48705..49535
                     /gene="thyA"
                     /locus_tag="PC466_000962"
     CDS             48705..49535
                     /gene="thyA"
                     /locus_tag="PC466_000962"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003518901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HDF2768357.1"
                     /translation="MSLADKIFIDMCNNILENGVSSDGEVVRAKWDDGQPAHTIKKFC
                     VVNRYDLSKEFPILTLRPTNLKAAIDELLWIWQKKSNNINDLNSRIWDSWADETGSIG
                     KAYGYQIGQKHKYKEGEFDQIDRVIYDLKYNPYSRRIITNIYNHNDLNEMNLYPCAYS
                     MTFNVTGNRLNAILNQRSNDILVANNWNVTQYAILVHMLAQISDLEVGELVHVIADAH
                     IYDRHIPLVKELINRESYDAPKLIINPNIKNFYDFRVEDFTLENYKSGPQIKKIPVAI
                     "
     gene            49548..50042
                     /locus_tag="PC466_000963"
     CDS             49548..50042
                     /locus_tag="PC466_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HDF2768358.1"
                     /translation="MKVIVAVDLNWGIGYGGKLLQSIPEDMKFFKEKTVGNVVVMGRE
                     TFKSLPGKKALKDRVNIVLTRSKSFNDDRLIVCNSIDETLKELQKYENDKIFIIGGET
                     VYKQFLPYCNELYVTKIQKTYEADRFFPNIDIMSNWDLIKESEVKEYNNIRYVFSTYI
                     NNSL"
     gene            50069..51445
                     /locus_tag="PC466_000964"
     CDS             50069..51445
                     /locus_tag="PC466_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HDF2768359.1"
                     /translation="MKKDIFVNRVSNALENDRGAVFVGSGISFSSTEVDWFKLLEPLV
                     NELDITLDNKSDDLPMIAQYIVNNYSGNRGPLVNEISKTFNRKFKLNKYHKYLATTKL
                     STIWTTNYDMLLEDAFYDFDTSVKVSDDSITRNRLEYDVEIIKMHGCISRSDWNEIVI
                     TQEDYDDFSINKPAISQRLSEDLINKSFLFIGYSYRDPNIRNIMINARRLSKKHTQQH
                     YIILKKLKDSDSNITQDDVVRQELWCNDLKRLGISTLFIDEYSELEELLREISQKSRG
                     KTVYVTGSHKESNMNARKLGTKLAKHKDITLLSGQSSGIGSEVVAAFTEECIKSKEDI
                     INRMKIFPNPYSADEKYSDDITLIPDLKKCRTKMLNSTQVVVVFSGGIGTEAEIDVAI
                     KQNCNIIPVITCKEDRENPAIKKILNYSDNMKNIEIKDATYYNKIVDEDGVVTMEEIY
                     ICISKIMN"
     gene            51421..52521
                     /locus_tag="PC466_000965"
     CDS             51421..52521
                     /locus_tag="PC466_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomethylpyrimidine synthase ThiC"
                     /protein_id="HDF2768360.1"
                     /translation="MHIKNNELKHDIIKLKKRNGFIEVGKDKKTLVNCLIGANELEDY
                     KYEIKKIDCILNISEKPDIVSDLSTKRRKISESIWYKIVKDTPFVSATLPIYLVSKNN
                     NKIDSNELLDIIIEQMENGVGMITIHPTANKQIFEDSKNRMVPVTSRGGGMVIQDLIS
                     KNFSEDNVYLKILPEIIKYAQKHNVCISLGATFRSGNIFDSNDRAQITEIKSQIELAK
                     RIYKSNVGVIIESPGHSRPSDIIKISSILKKEGFPIMPLGPIPTDIAIGMDHIAAAIG
                     ATIMGIEGCANIISTVTREEHTGGRPSIESTVESIRTAKIAAHIIDIHQMNDINLDMS
                     VSKSRAKSNTCIFGKDTRYCDRCRELCPLCIR"
     gene            52564..52989
                     /locus_tag="PC466_000966"
     CDS             52564..52989
                     /locus_tag="PC466_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent thymidylate synthase"
                     /protein_id="HDF2768361.1"
                     /translation="MHRIASFSQQSQRYVKLEQFEYIIPPEIEKIEKAKELFINSMKK
                     YQEDYDKLVEILFENHYNKLIKGGKNEKTSKRQVEKKAIEDARYVFPNACETKMVFTI
                     NARSLFNFFEHRCYENGSCLEGTMTCGDIVQVRKKFKNL"
     gene            53002..53739
                     /gene="rlmB"
                     /locus_tag="PC466_000967"
     CDS             53002..53739
                     /gene="rlmB"
                     /locus_tag="PC466_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HDF2768362.1"
                     /translation="MASIEGRNPVIEAIKSDREIDKILIANSAKEGSIKKIIGMAKDK
                     NIIIQYVDKHKLDEVSTSHSHQGVIAYASEYKYYELDELIDLAKNKDEDPFFIILDEI
                     TDPHNLGSIIRTADAVGAHGVIIPKRRSVHITPVVAKASAGAVEYMPVCKVTNIVNTI
                     KRLKEEGLWIAAADMDGETFYKQNLTGPLGVVIGSEGFGISRLVKQNCDFIVKMPMIG
                     NVTSLNASVAGGILLYEIFRQRLDKSK"
     gene            53742..54269
                     /locus_tag="PC466_000968"
     CDS             53742..54269
                     /locus_tag="PC466_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HDF2768363.1"
                     /translation="MKKNINHYLIIDGYNIINAWDNLKELAKEDLEDSREKLIDDIIE
                     FSEFMGYKTIIVFDAYNVKNSREKVEKRKHITIVYTREHQTADSYIEKFITSLSKYDD
                     VKVATNDYAEQQMILGKGATRMSARELKLELDRSKNKMKEKNIGLRKKIQRNWLEERL
                     DKETLSKLENIRRKR"
     gene            54334..54981
                     /gene="sigH"
                     /locus_tag="PC466_000969"
     CDS             54334..54981
                     /gene="sigH"
                     /locus_tag="PC466_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigH"
                     /protein_id="HDF2768364.1"
                     /translation="MLVAKEKSYELVDNCQQDEYNIVLRASEGDKIALEYIITKYRNF
                     VKAKAKSYFLIGADKEDIIQEGMIGLYKAVRDFDGSKTNSFKCFAEICITRQIITAIK
                     TATRQKHIPLNSYVSLNKPIYDEESDRTLLDIIATSIVTDPEELIISKEELKNIESKM
                     NELLSDLELEVLELYLNGKSYQFIADKLKRDVKSIDNALQRVKRKLEKHLENRND"
     gene            55055..>55446
                     /locus_tag="PC466_000970"
     CDS             55055..>55446
                     /locus_tag="PC466_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosome-binding GTPase"
                     /protein_id="HDF2768365.1"
                     /translation="MAKAKYERTKPHVNIGTIGHVDHGKTTLTAAITKTLYDRYQLGE
                     AVDFANIDKAPEERERGITISTAHVEYETPNRHYAHVDCPGHADYVKNMITGAAQMDG
                     AILVCSATDGPMPQTREHILLSRQVGVP"
BASE COUNT        22584 a         5938 c        10470 g        16454 t
ORIGIN      
        1 ccccttccag gtcgccaaaa taaaatgctg gtgtggctca acggtagagc agctgacttg
       61 taatcagcag gttgtaggtt cgattcctat caccagctcc atgtaaaatt aatacggagg
      121 atttcccgag cggccaaagg gggcagactg taaatctgtt gtcatcgact tcggtggttc
      181 gaatccacca tcctccacca aaaaaatgcg cggatgtggc ggaattggca gacgcactag
      241 acttaggatc tagcgccatt ggcgtggggg ttcgactccc ttcatccgca ccatttttat
      301 ttaatttaat aaacgagcgg gaatagttca gtggtagagc gcaaccttgc caaggttgaa
      361 gtcgcgagtt cgaatctcgt ttcccgctcc aaattttatg tttatgttgt aatgtgggtg
      421 catagctcag ctggatagag caacgccctt ctaaggcgtg tgtccggggt tcgaatccct
      481 gtgcgctcac cacatatata ttggggatta gccaagtcgg taaggcacat gactttgact
      541 catgtatgcg taggttcgag tcctgcatcc ccagccaaac agtatggtct attagctcag
      601 tcggtagagc acctgacttt taatcagggt gtcccgcgtt cgagtcgcgg atagatcacc
      661 aatggagagg tgtccgagtg gtttaaggag ctggtcttga aaaccagtga cttcgaaagg
      721 ggccgtgggt tcgaatccca ccctctccgc caaatgccca gatagctcag tcggtagagc
      781 aggggactga aaatccccgt gtcggtggtt cgattccgcc tctgggcacc aaaatgtggc
      841 ggtatagctt agttggctag agcgttcggt tcatacccga aaggtcatag gttcgactcc
      901 tattaccgct actaaaattt aatgtgggcc attagctcag ttggttagag cgcccggctc
      961 ataaccggta ggtctggggt tcgagtccct gatggcccac cacattaaat taacttatgg
     1021 tgggtatagc tcagttggtt agagcgccag attgtggctc tggaggtcgt gagttcgact
     1081 ctcattatcc accccaactt atatggtcta ttagctcagt cggtagagca cctgactttt
     1141 aatcagggtg tcccgcgttc gagtcgcgga tagatcacca aaaaggcggc gacatagcca
     1201 agtggtaagg cagtggactg caactccttg atccccagtt cgaatctggg tgtcgcctcc
     1261 aataaaatgc gctcatagct caactggata gagtgtctga ctacgaatca gaaggttagg
     1321 ggttcgagtc cctttgggcg caccatatga atagcgaggg attatagctc agctgggaga
     1381 gcacctgcct tacaagcagg gggtcacagg ttcgagccct gttaatccca ccagtgcaaa
     1441 cctctagtaa aactactaga ggttttattt ttgattgaaa aagtttttat atttaggagg
     1501 taagaaattt gtatatagta ataggaaatg aaatagttga tagtgaagaa cttaaaataa
     1561 ttatagatga aaatagtaaa tttaaagttg aaaaagattt aagtaaaagc acaaaaagag
     1621 aagatgtaat agcatatcag ttaagtatag atttaaatta cctagattct cttataaatg
     1681 agcaatgtaa tttgtccagt ttatctgatg aagagaaatt tgatgaatat atgactttgt
     1741 ctgatgaact tgcactggat ttagaagagt taatgccaaa atatacaata ataaatgcta
     1801 gagcatataa attagacgag gtagatggaa ttgtaaaaat aatactagct gtagcgtatg
     1861 cagatttagg gcacttaaaa ctttctgatg tagtaaagag gctatctaga caagtagatt
     1921 aggatatgaa tatgaactat attaaaaaaa tgtataaaat cttacgtaaa gatgaaaata
     1981 attatgtaaa catagaaaaa aacagtataa aatcaagtca attgtagaaa ttttcacata
     2041 aattcatctg aaattctata aaaaatgcct taattttaat gaggtaaatc gagtttacac
     2101 agtctaaaaa ttacttatat ttataaattt atcttattaa ttaaggaact ttcttaaaca
     2161 tcttcaaaaa taaagtattt tagtctataa tctttaatat tacacaaaca ataaaggaga
     2221 agaatagagt atgcttaaaa agtttaataa aatactagtg gctaatagag gcgaaatagc
     2281 tataagaata tttagagcct gttcagaatt ggggataaaa agtgttggta tatacagtaa
     2341 ggaagataag tatggattgt ttagaacaaa agcagatgaa tcatatttga taggagaagg
     2401 taaagggcca atagatgcat atttagatat ggatggaata atagacctag caaagagaaa
     2461 aaaagttgat gctatacatc caggatatgg ttttctagcg gagaatgcag aatttgctcg
     2521 taaatgtgaa gagaatggaa ttacttttat aggaccatca tctaaggtaa tgaatatgat
     2581 gggggataag attaactcta aaaaaatcgc aaaagaagtt aatgttcaaa ctataccagg
     2641 agtagaaaaa gcaataagaa gtactgaaga agcaaaggaa gttgcaaaca aaataggata
     2701 tcctgttatg ataaaagcat ctaatggcgg tggcggtaga ggtatgagaa ttgtacatcg
     2761 cgaagaagac ttagaacttg aatatgaaac tgcttgtagt gaatcaagaa aagcttttgg
     2821 agaagatatt atatttatag aaaaatatat agctgatcca aaacatatag aagttcaaat
     2881 attaggtgat aattatggaa atatagttca cttatatgaa agagattgtt cagttcaaag
     2941 aagacatcaa aaaataatag aatatgcacc agctttttcg ttagatgata aagtaagaaa
     3001 agagatatgt gaagatgcag ttaagttatc aaaacatgtg ggttattcta atgcgggaac
     3061 attagaattt ttagtagatg caaatggtgg gcattatttt atagagatga acacaagagt
     3121 acaggttgaa catactgtaa cagagatggt tacaggaata gatatagttc aaagtcaaat
     3181 actaatagcc caaggttaca gcttagatag tgaagaaatt aatataaaat cacaagatga
     3241 tgtggaaata agaggttact ctatccaatg tagaataact acagaagacc ctaagaataa
     3301 attcatgcct gatacaggta aaattcaagt ttatagaact ggttcaggat ttggtataag
     3361 actagatgga ggaaatggat ttacaggggc aaacataagt cctcattatg atagtttatt
     3421 ggttaagaca atatcttggg atagaacatt ccaaggagca ataaataaaa ctataagatc
     3481 tataaaagaa cttagagtta gaggtgttaa aactaatgta ggattcctag ttaatgtttt
     3541 aaataatcct atattctcaa atggtaaatg tagtactaag tttatagatg aaaatccaga
     3601 tttatttgaa ataacagaaa gtaaagacag aggaacaaaa ttacttcaat ttataggaga
     3661 tgtaattgta aatgataatg cttgtaaaga aaaaccacta tttgatgcat tacatgaccc
     3721 aagaatggat aaggatggtt caaaatcaga aggaagtaaa atacttttcg ataagttagg
     3781 taaatctgca tatatagaaa agataaaaaa tgataagaaa ttactattaa cagatacaac
     3841 aatgagagat gcacatcaat cattattagc aacaagaata agaacatatg acttattaaa
     3901 agctgctaag ccaacagaaa aatatcaaaa ggatttattc tcacttgaaa tgtggggagg
     3961 agctacttat gatgttgcat atagattttt aaaagaatct ccttggcgta gattacaaaa
     4021 gctaagagaa gaaataccaa gcataatgtt ccaaatgttg cttagagcat caaatggagt
     4081 tggatataaa aactatccag ataatgtaat agaagaattt acaaaagaat ctgctagaca
     4141 aggtatagat gtatttagaa tatttgattc attaaactgg gttgaaaata tgaaaccatc
     4201 tattaataca gctttagaaa ctggaaaaat tgttgaagca actatgtgtt atacaggtga
     4261 tatactagat aagactaaaa ctaaatacaa tctagaatat tatattaaaa tggcacaaga
     4321 attagaaagc ttgggagcag atataatagc aataaaagat atgtcaggtc ttcttaaacc
     4381 atattcagct tacacactag ttaaagagtt aaagaaaaat gtaaaagcac caatacattt
     4441 acacactcat gatacaagtg gaaatggtgt agcaacttgt ttaatggcgt cagaagctgg
     4501 agtagacata attgatgctg cattagaatc tatggcagga cttacaagtc agccatcgct
     4561 taatgctata gtagaggcac ttaagaatac agagagagat acaggaatag atttatttgg
     4621 atatgatgag ttaggaaaat attataagga tttaagaaaa gtttataata aatttgaaag
     4681 tgatttaact aattcttgtg cagaaatata taattttgaa ataccaggag gccaatatac
     4741 aaacttaaaa cctcaagctg atagtttagg attagttaat agatttgatg aagttaaaga
     4801 aaaatataaa gaagctaatg aagttgtagg agatataata aaagtaactc catcttcaaa
     4861 agttgtagga gacttagcta tctttatgac taaaaataaa ttagataaag acaatataat
     4921 agaagaaggt aaaaatttat cattcccaga ttctgttgtg gattactgta aaggtatgat
     4981 tggtcaacca gaaggtggaa taccaaaaga tttacaagag gtagttctaa aaggtgaaga
     5041 agctataaca gtaagaccag gttcattatt accagcagaa gattttgatg aaatagctaa
     5101 atatctaaat gaaaagtatg atataaatgc taatataaga aatgttataa gttatgcttt
     5161 atatccaaaa gtatatgaag attatatcaa acatctacaa cattataatg atatatctaa
     5221 acttgaaagt gatgtattct tctatggatt aaataaaaat gaagaatgtg aagtagaaat
     5281 agaagaaggt aaggtattaa caataagatt agttgaaatt ggtgaagtta aggaaaatgg
     5341 atttagaact ataggatttg agttaaatgg aatggttaga gaagtagaaa taaaagataa
     5401 gaatttctct ggaaaaatta ataatgttga aaaagctgat atgaatgacc ctcttcaaat
     5461 tggagcaagc ataccaggaa aagttataaa aataatggtt aaagaagaag atgaagtaaa
     5521 agcaaatcaa ccattaatcg ttatagaggc tatgaagatg gaaactataa tagttgctaa
     5581 gactgatgga gtaattaagt caatcaaagt aaaagaagat gatatggttg aagataaaca
     5641 attattaatg ataatgaagt aatttaatta aaataaatta aaaagcactc tgaaatgttt
     5701 aataaaaaat gttttagagt gtttttattt attttaatta aatatttgtt aaaaaaaaga
     5761 ggacaattac ctccagatgt agaaataaag ctagtaagga aaatgttatc taaaaattct
     5821 aaatatagta aatattttcc ataatatttc ttaggaaata acagcaaaga taaaatacat
     5881 aaatttaaaa ggtgggtgct tatatgaagg tttatgatag taaaatgttg agaaatgtag
     5941 cagtattagg acatagcgga tgtggaaaaa caaatctaat cgaaactata gcttacacag
     6001 caaacactaa taagatacct aaattaacag acaaggtaaa tatgacttat agcatgggat
     6061 taatacctat agagtataat gattataagt ttaacttatt ggatacccca ggatattttg
     6121 actttagcgg agacgttgtg tcatctctta gagcaagtga tgcagcaata atagtaatag
     6181 atgcaacagc gcctattcaa gttggtacag agaaatcatt agaactaact gagagtattc
     6241 ctaagataat gtttataaat aaaatagata atgaaaaggc aagatacaaa gatgcaatag
     6301 caatgttaag agaaaaatac aataataaga tagttcctat gataagtcct atatacaaag
     6361 ataaaaactt tgtaaagtta cataatgttt ttgaaaacat agatgattta gaaggtgaat
     6421 ttaaggaaca agctatgagt gttaaagaag cattaatgga acttatagca gaaactgatg
     6481 accaaatatt agataaatat tttaatggag aagaactaac tacggaagag atacaaaaag
     6541 gtattattat aggtatacaa agaggtgata ttatacctgt aatatgtggt tcaactataa
     6601 ataatatagg cacaaaggaa atattagata caatatcaag ttatttagaa cctatcttta
     6661 cagaggaaag caaaccattt aggggattag tatttaaaac tatggttgac ccatttgttg
     6721 gaaagatgtc atatataaag attactgagg gtgtactttc taaggataaa gatgttttta
     6781 atataaataa aaatgtaaaa gaaaaaatag ctaatatata tacattgaga aatagtgaat
     6841 tagtagaaat agaaaaagct aaagctggtg atatagtagt tataactaaa gttaattctc
     6901 taaaaacagg agacactata tctgcagata aagatgcaga agctttagaa aagatagatt
     6961 ttcctaaacc acaaatatat tatgcagtaa ctcctaagaa taaaggtgat gaagaaaaag
     7021 tagcatctgt attaaataaa ctagtagaag aggaccctac attacattgg tatagaaata
     7081 cagagacaaa acaagcactt ttaggaggtc aaggagaact tcatataaaa acaattaaaa
     7141 ataaaatgaa agataagttt ggtgttgatg ttgaattgaa tgaccttaaa gttccttata
     7201 gagaaactat aaaaggaaca gccgatgtac aaggaaaaca taaaaagcaa tcaggtggtc
     7261 atggtcaata tggagacgta aaaataagat ttgaaagatg tgaatctgat tttgaattta
     7321 cagaagaaat atttggtggt tctgtaccaa aacaatatat accagcagtt gaaaaaggtc
     7381 taaaagactc tatgcaaaaa ggtatattag caggttatcc tgttacaaac ataaaagcta
     7441 cgctttatga tggttcatac catgatgtag actcttctga aatggccttt aagatggcag
     7501 caagtgcagc ctttaaaaaa ggtatggaag aagcgcaccc aatactacta gaacctataa
     7561 tgaaacttaa gataactgtt ccagaagaat atatgggaga tgtcatgggt gatataaata
     7621 agagaagagg aaaaatattt ggaatggaac cagatgacaa agggaaacaa ataatatttg
     7681 cagaagctcc acaagcagag acatttaaat atgcaataga tttaagagca atgacacaag
     7741 gtagaggata ctttgaaatg gaattagaga gatatggaga ggttccatca cagtttgcag
     7801 aaaaaataat tgggttagct actgcaaagt aatgaacaaa ataaatagaa aaataattaa
     7861 tatatattat taaaaatatt tttagggttt taactaggta taggtttatg ttaggtaaac
     7921 ttatacctag tttttataca tttttgatga ataaaaaaat atataatact ttcttaaatg
     7981 ttttaataaa aagaaagtat ttttttatta ttatttttac aaatgtttag taataaagat
     8041 gagaaggtat atttaaaata taaagtattt aaagttctga aatctaatca tgaagcaaaa
     8101 aattagcatt tggttatcaa taaatataat aaataaaaac tcataattaa tgaaagaata
     8161 aattcatatc taaatttcta taaaaaattt aaatttatac aatttagggc tttaaaaatt
     8221 taaataatag gtgtaaaata atagtcaaag aaagtcaaaa ataaaaaggt gtgtggtgat
     8281 attaatggca actatgacag atataattga aaaatttatt aaagatttga tggaagaaga
     8341 taatagcata caaattcaaa gaaatgaact agcaaacttg tttagttgtg caccatcaca
     8401 aataaattat gtcttaacaa caagatttac aatagataga ggatattaca ttgaaagtaa
     8461 aaaaggtggc ggaggatatg ttcaaataga aaaaatacga aaaagtaaag atggacatat
     8521 tagagaacta ctaaatgaaa aaataggaag tcagatatcc tataaaaaag caaaggaatt
     8581 attagaaggt ttaaaagagt cggatttgat taacgaaaga gaattaaaat taatattata
     8641 tgcaatagat gataaatcat tgtgtatgcc aatatatgaa ttaaaagaga aggtaaggtc
     8701 taatatttta aagaatataa taataggatt atttagtata gaggagtgat aatttatgct
     8761 atgtcaaaaa tgcaataaga ataaagcatc tgtatattat aataagatag tcaatggaga
     8821 aaaaacagag atgtatttat gtagtgagtg tgcaaaagag aatacagaaa tgaattttaa
     8881 cttagatatg cctttttcaa tgatggatat attttctaat ttaggttttc aacctaaaaa
     8941 agaacttgag gaaaagctag tttgtcctaa atgcaataca acatatagtg agtttaagaa
     9001 taatgggaga tttggatgta gtgaatgtta taatgcattt agtagtcaag taaatccaat
     9061 gcttcaaaat atacatgggc atatagaaca tacaggaaaa gcacctaaaa aatcttttta
     9121 taagataagt gtagaaaatg agattaaaga actaaaagaa gatttagata gagctataaa
     9181 aaatgaagag tatgaattag cagctcaatt tagagataaa attaaatatt taaaaggttc
     9241 tattgactaa gattggagtg atattatgaa agagaacata gtcatgaaat caagagttag
     9301 gctagctaga aatttaaata actatccatt tccaaataaa ttagataaag aatgtgccat
     9361 ggaaataata gaaaaagtaa aaaatgcgtt tattaattct aacttagaac aaaaagaaga
     9421 atttgatttc tataaaattg aagatttaga ccaatctaaa aaaatgctta tggttgaaga
     9481 acatataata agcccagatt tagcagaaaa tgataaaagt gcagttatag taaaaaaaga
     9541 taaaactata agcataatga taaatgaaga agaccatata aggatacaaa ctatatgtga
     9601 tgatttaaac ttagaatatg catatagtgt agcaaatgaa atagatgatt tgttagaatc
     9661 aagtttagaa tatgccttta acacaaagct aggttatcta acatcttgtc caactaatac
     9721 aggaacagga atgagagctt ctgtaatgat gcatttacca gcattaagtc aactaggcta
     9781 tatggatgaa ctttataaaa tttcatcaca aataggtata gcaattagag ggatatatgg
     9841 agaacgaaca gaagcattgg gaaatatata tcaaatatct aatcaactta cacttggaag
     9901 aacagagtct aatattatag aaaatgtaag tggacttaca aaagatgcaa tttcaaaaga
     9961 aataaaagct agagaaatat tgcaaaaaaa attaggtata aaactagaag ataaaatatt
    10021 tagatcgata gggacacttg aaaattcaag agtaatgagt agcgcagagg caatgagcca
    10081 tctatcaaat ataaaaatgg gaatagaaat gaactatata gataaactag atttaagggc
    10141 tatagaacaa cttatgatag gtatacaacc agcgcatcag tcaataatgt ataagagtga
    10201 tgatgttgag aatagagata taaatagagc aacatatatt agagaaactt tggaaaaatt
    10261 aagaggaggg atgaattgtg aacttcaata gatttacaca aagagctaaa aaggcaattg
    10321 atttagcgtt tgaatctgct aaaagtctag gacacaatat tgttggaagt gaacatatac
    10381 ttttaggtct tttaagagaa gaagaaggta tagctgctaa agttctaagt aaagttggat
    10441 ttacagaagc ttatttagaa ggcaaaatag ttgatatgga aggtaaggga gaagaaatct
    10501 cagaagatat agtattaagt ccaaggagta aacaaatact tgaattatca ggaatgtttg
    10561 caaataaatt aaaaacaaat tatattggga ctgagcatat attattagca attattcaag
    10621 aaggtgaagg aatagctaat aagattttaa attatgctgg agtaaatgat aggactttag
    10681 cccaattaac aattgatatg atgggtatta gtgataaaaa tcaatacaaa gcagagaata
    10741 gttacacggg caaccagaat caagcagaat ctaaagtact tgataagtat ggaagaaatc
    10801 ttacactata tgcaaaacag aataaaatag accctgtaat aggtagagaa aaagaaatac
    10861 aaagagtaat acaaatatta agtagaagaa ctaaaaacaa tccagtgttg ataggagacc
    10921 caggtgtagg gaaaacagcc atagctgaag gtctggctac aaatatagcc ttaggaaatg
    10981 ttccagaaac actaaaaaac aaaactttat actctttaga gatgggttca ttattggctg
    11041 gggctaagta tagaggagaa tttgaagaaa gaattaaaga agttgtagat gaagttgtta
    11101 aaaatggaaa cataatctta tttatagatg agatgcacac aataataggg gctgggtcta
    11161 ctggagaagg ctctatagat gcttcaaata tattaaagcc agccttggca agaggagaaa
    11221 tacaagttat aggtgcaact acaattgatg aatatagaaa gcatgttgaa aaagattctg
    11281 ctctagaaag aagattccaa ccagttatgg tagatgaacc aactaaagag gactcaataa
    11341 aaatattaga aggattaaga gataaatatg aagctcatca taaagttaaa ataactgatg
    11401 atgctataaa ggcagctgta gaattatcaa ctagatatat atcagacaga tatctgccag
    11461 ataaagctat agacttgatt gatgaagctg catcaaaagt aagattaaaa gaaaatacac
    11521 ctccttcaga aataaaaaaa ttagaactag aaatagaaaa tatagataaa gaaaaagaag
    11581 aagcagtaag atgtcaagac tttgagaaag cagccaaaat aagagatgaa caaggtctac
    11641 ttaaaaaaca attagaagat gttagagaaa gatggaacaa gtcatctaaa cattcagatt
    11701 tagttgatgg agaagttatt gctgaagtag tgggcttatg gacaggaata ccagttaata
    11761 aaattcttga agaagaggct gatagacttt tgagacttga ggaaatactg cacaatagag
    11821 ttataggtca agaacaagca gtaaaatcta tttcaaaggc aatcagaagg tcaagagcag
    11881 gtcttaaaga ccctaataga ccaattggtt catttttatt tttaggtcca acaggagtag
    11941 gtaaaacaga attatctaag gcattagcag aagtgcaatt tggagatgaa aatcaaataa
    12001 ttagaataga tatgtctgaa tatatggaaa aacatgctgt gtcaagaatg ataggttcac
    12061 ctccaggtta tgtaggtcat gatgaaggtg gtcaattaac tgaaaaagta agaagaaatc
    12121 catattcagt tatcttattt gatgagatag aaaaagctca tccagatgta tttaatattc
    12181 tgttacaaat tctagatgat ggtagactaa ctgattcaaa aggaagaact gtagatttta
    12241 agaatactat tgtaataatg acatcaaatg ttggagcatc tacaattggt agacaaaaaa
    12301 ctttaggatt tagtatagct aaaggagacg aagaagaaaa atctcaatat gaaaaaatga
    12361 aagaaaatat aatgggtgaa ttaaaacaaa gattcagacc agagttttta aacagaatag
    12421 atgatataat tgttttccac tcactaaatg aaaatcatat atcaaaaata gtacttttaa
    12481 tggcagcgaa actacaagag agattaaaag aaatggatat aaaattagaa atgagtgatg
    12541 aggctgttaa attaatttct aaatctggat ttgacttaga atatggagca agacctctta
    12601 aaagagcttt acaaaaagag ttggaagatg agctatctga agcaatctta aaaggtaatg
    12661 tgaaaaaggg aagtaatgta gtagcaaaag tcaaagatga aaaaatagtt tttgaaacta
    12721 aataatttaa tagagttgca ttttaaaata ttgcaaatat aagttttata atctaaacaa
    12781 aattttaagg gcaatgaatc tataataatt cattgtcctt aattatttta tttaatcttt
    12841 acatattgtc tttcagatat gctaaaatta tagtatagaa taaaaaatta aggatgataa
    12901 aagtatggca aaaataaaaa caaaatatgt atgtcaatct tgtggatatg aaacagctaa
    12961 atggcttggt aaatgtccag aatgtacaaa atggaataca tttgtagaag aaatagacca
    13021 aaaaagcacc aaaaaagagg tctttataat agataaatct tcatctaaac cagtcagtat
    13081 aaactcaata gaaagtaaag aagaagagag gtttacaaca gatataaatg aattagatag
    13141 agtgcttgga ggaggtatag ttaaaggctc tttagtgctt gttggtggtg accctggtat
    13201 aggtaaatca acacttttaa tccaagtatc tagtaatgtt gccaatttag gaaaaactgt
    13261 tttatatata actggagaag aatcagaatc tcaaataaaa atgagagcta aaagattagg
    13321 tattaactca gaaaatttat atatatttgc tgaaaataat ttaagtataa ttgaatctta
    13381 tttagaaagt gtaaatccag aattaataat tctagactca attcaaactg tcttcagtcc
    13441 agaaatatcc tcggcaccag gaactgtcag ccaaattaaa gaaggtactt caaaattcat
    13501 gaaaatttct aaaaaaatgg gaatttcaac gttcatagtt gggcatgtta caaaagaagg
    13561 ttcactagca ggaccaaaat tattagagca tatggttgat actgttctat attttgaagg
    13621 agaaagatat aatacttata gattagtaag agctgttaaa aatcgatttg gttcaactaa
    13681 tgaacttgga gtatttgaaa tgagggattt aggattagta gaacttgata atccatctaa
    13741 aattttaatc tctgaaaaac caaaagatgt agcaggttca gtaataatat ctactgtaga
    13801 aggtacgaga ccaatgttac ttgaattgca agcattagtt tctcctacaa gttttggtat
    13861 accaaaaaga acatctacag gagtcgatta caatagagta ggtatgttat tagcagtatt
    13921 agaaaaacgt gttggtttgc aaatacaaaa tcaagatgtc tatataaaca tagttggagg
    13981 aataaagata aatgaaccct caattgattt agggatagcc atttctgtag catctagttt
    14041 tagaaatata ccgatagatg aaaatatagc tgttacagga gaagtgggac ttacaggaga
    14101 agttagagca gtaagcttta tagaaaagag aatagctgag tgtaaaaaac ttggatttaa
    14161 aaagatagta gttcctagaa gtaattatga tgttgtaaaa gagaccaaag gcatagaaat
    14221 atggccagta gataacttaa gacaagctat aaatatagta cttgggagga atcaataaat
    14281 atggagaatt ttctagataa taaaaatatg ctatatgcat taaaaatgat atctcctgga
    14341 actccactta gattaggtct aaacaatgta ctaagagcta agactggtgg attaattgta
    14401 attgcaacaa acgaagatgt aatgaaaata gtagatggag gatttgctat aaatgcagaa
    14461 tattcaccat catatctata tgaattagct aaaatggatg gagctatagt tttaagtggt
    14521 gatgtaaaga aaatattatt tgctaatgca caacttatac ctgactattt tatagaaaca
    14581 tcagagacag gaacaagaca tagaacagca gaaagagtag caaaacaaac tggtgctata
    14641 gtcataggaa tttcacaaag aagaaatgtt ataacagttt atagaggaaa tgagaagtat
    14701 gtagtcgaag atatatctaa gatatttact aaggcaaatc aggctataca aactctggaa
    14761 aaatataaga cagtattgga ccaagctgta acaaatttaa atgccttaga gtttaatgat
    14821 ttggtaacta tttatgatgt tgcattagtc atgcaaaaga tggaaatggt aatgagagtt
    14881 acaagtataa ttgaaaaata tgtgatagaa ttgggtgatg aaggaacttt agtaagtatg
    14941 caattagaag aattaatggg tacaaccaga atagaccaga aattaatatt caaagattat
    15001 aataaagaaa acacagaaat aaaagaactt atgaaaaagg tcaaaaattt aaattcagaa
    15061 gaactaatag aattggtcaa tatggcaaaa ctattagggt atagtggttt ttcagaaagt
    15121 atggatatgc ctataaaaac aagaggttat aggattctta gcaaaataca tagactacca
    15181 acagcaataa tagaaaactt agtaaattat tttgaaaact ttcaacaaat tttagatgca
    15241 tctattgaag aattagatga ggttgaagga ataggtgaaa taagagcaac atatataaaa
    15301 aatggactca taaaaatgaa acaattagtc ttattagata gacacatatg atgaatttta
    15361 aatgaatttt actacttttt tcttgaatat aatatacact ttggtctata atagataagt
    15421 ataactaggg ggtgaagcat tgataaggaa agtaacaaga atattgttta ttttacttgg
    15481 atttacaata ggtataacaa cctatttaac attaatgaaa gattttgaaa tattaacatt
    15541 tggaaaagaa acatatggtt atatcgcagc tgtagtagca ggtataataa tagccatttt
    15601 aggatatctt atagaaccat gggttgtaaa taaagtaaaa gaaattgcta aaatagtgga
    15661 taaagaattg tcaaaatatc ctcagactga tatattgtta gggtctatgg gtcttatagt
    15721 aggatttgtt attgcgtatt tattaagtgg attagtaaat agaataccaa tagtaggtgg
    15781 aatactatcc ttactattat atttattcct aggatatctt ggaatgaaag ttgcgcttaa
    15841 aagtaaaaat gatttattta atattggaaa actaggaaga ttagcaaatc ctattaagga
    15901 taaagataag gataaagaaa ataaaaaaga agtaaaagcc attcctccaa aagtattaga
    15961 tacaagtgta ataattgatg gaagaatagc tgatatttgt aagactgggt ttatagaagg
    16021 aaaacttatt attcctgctt ttgttttgga ggaactaaga catattgcag attcttcaga
    16081 tgatttaaaa agagtaagag gtagaagagg tctggatata ttaaatataa ttcagaaaga
    16141 attaaatata gaagttgaaa taagtgagag agactttgat gatatagcag aagttgatag
    16201 taaattatta aagcttgctc aggttttaaa tggaaaagtt gttacaaatg attataactt
    16261 aaataaagtt gctcaattcc aaggtgttga agtattaaat ataaatgagt tagctaatgc
    16321 tataaaacca gttgctatac caggtgaaga tatggttgtt caagtggtta aagaaggaaa
    16381 agaggctcaa caaggtgttg catatctaga tgatggaact atgatagttg ttgatggagg
    16441 aagaaaatat atgaatgaga ctataaaagt actcgttact tctgttcttc aaactcctgc
    16501 aggtagaatg atatttgcaa aacctaaaaa ttaatatgtt caaagaaacc tataatttgg
    16561 gctgtttatt ttaaatagat ggtccaaatt tatttattta taacgataat gtttaatgta
    16621 ttcttaaaga tggggattta aatcagaaag cagggagaat ttatgagaaa aaagattata
    16681 tctttcttag caacatttat cataatatta acatcagcaa gtcagtatag ttttgcagat
    16741 gatatgtcaa cacgtggaaa agtaatattt atagatatga atagaactag tatgagtaat
    16801 atgttaagaa taaaatcatt aagagaagaa ctagacaata gagggtatat tggcttgatg
    16861 aatataagag gcgataaagg aagtgatgat agaaggtcat atgctagtat gggtgctggt
    16921 ggtagagcta atgtggctaa tgaagaagat attaattttg aaagctcgag taaggataga
    16981 aatatagttt ttgaatcagc tacaggaaaa agtgcaaaag gtataaataa tttaactata
    17041 aataagtcta taaatgaaaa tttaaacttt ggagagtatg gttctgtatt agggtcatta
    17101 ggacaaagtt tatctgagaa tggattaaaa gcatctgtat tgggtaattc agatataatt
    17161 gaaaatggtc aacttataaa aaatagaaac ttatgtctaa ctgcaatgga tgaatatgga
    17221 agaataccta atggaaatgt agatactata aataaaaaag acttatctat gccttatgga
    17281 atatcaactg attatgataa attgattgta gagaccaaag aagcttacaa aaataatgat
    17341 gtggtttttg tggagcttgg agacacatat agattagatt tatataaacc aaatttaaat
    17401 gaaaaaacat atgagagtgt gaaagataac atagaaaaaa atatagatgt atatttaaaa
    17461 aatatatttt ctatggttga agaaaatgac actgtctaca tagcaagtgc atttccaagt
    17521 gatttagatt ataaaaataa aagaagactt tctccaataa taaaattaaa tggagaaggg
    17581 aaaggtatat tatcatcttc aactactaga agagaaggta ttgtaacaaa tttagatgtt
    17641 ggggttgaaa tattagacaa ctttaatata aaaaatcaaa atatggttgg aagaaaatat
    17701 gaacttatta acagagatga taataaagaa tttttgatgg atgaatatca aaagatagta
    17761 tctatttcaa gcataaggtc tacaatactg aatggttttg taagtatagt tttcttgtca
    17821 tggatagttg ctatgattgc aattttattt agaaagcata tatcaaaaaa ttataaagaa
    17881 acaacatttt ttatattaaa ggaactttta aaaataggaa tagtaatgcc actgtcattt
    17941 atgataacac caataatgaa tttcaaaaca ccattagcaa tatctttagg aataattata
    18001 ataacactta ctatatatct tataagtaaa gttttaataa agaatgattt aaaaaacatg
    18061 ctgtttttta ctggattaac catagtaatt atggttattg atgctgggtt tggctcatat
    18121 ttaatgaaaa gcaatgttat gagttatgac tgtataattg gagctagata ttatggagtg
    18181 ggaaatgagt atcaaggtgt ggcaatcggt agtgcaatat ttacatttgc aattttactt
    18241 acatataaaa atataccaaa gtggtctata atagtttttt ctttggttat cttaattaca
    18301 agtgcatctc caattatggg agcaaatgtt ggaagtgcta tttctgaatg tgttgcattt
    18361 ttactattta tactattgat atataatgtg aagatagact tcaaaaaaat tgtattatta
    18421 ggtatagcag tattatttgt attaggagtt tttgtagcaa tagatatgat tttgggaagt
    18481 aattcacatt taggtatgtt tgtaaaagaa atttacttta atggaccagg agaaataata
    18541 caaacattta gtagaaagat agagatgaat ttaaagctag ctcaaaccag tgcatgggta
    18601 aatatactgt taactggaat aggtgtaatt ttagttctta tgattaatca gattagatac
    18661 tttaagcaac tgatggatga gtatccaatt gtatttaaag gatttatagc atcaatagca
    18721 ggatgtttag taactctttt agtgaatgac tctgggattg tgtcatcagc tacagccttt
    18781 atttatgtaa ttgtacctat gataacatta agtataaatc tcacagcatt aaaagaataa
    18841 gtactgtatg aataatatgt aaatatgaac acattaattt aacttcttta tttacaaaat
    18901 aaagaagaaa gtttataaaa aataaattat aataaaaaag agtttacctc aaaattgatt
    18961 attctaatca aattttaagg taaacttttt ttattataaa gataaataac atataacctc
    19021 atattttagg tagatttttt tcttatatgt ttaggagtgc atttaaattt ttccttaaaa
    19081 attctgtaaa ataattttgt attagtaaat ccatgagctt ctaatatact gcataaggta
    19141 tcatttgtgt taattaagtc tttataaata tgagaaatac gcacatcatt taaatactct
    19201 aagtaagttt gtcccatata ctgtttaaat tttctacaaa aatattctgg ctgtaagtgt
    19261 gctaccttag cgattttgtt aatagaaata ggcattttgt aattaatctt tgtatattct
    19321 aaaactggtt caaattttga caaatcaagt actgtttttt tcatattttt attacctaca
    19381 gatattttaa agtttgtata taattcaaat aaaagttcaa ataataagct tgtaaagagc
    19441 agattagctg caggaggaga gctaagttta atttctctca tgttttctaa tataagttta
    19501 actttacctg aatttttttt atagttattg tcattggcat taaccttaaa gtcaaaatag
    19561 caatttttaa aatcagggat atatttgttt agaaaagaca atggtacttg caataatata
    19621 gaggtatctt gataagtaca tctagttgag tgaataattc cagaattaat gaacatacac
    19681 tcattagctt ttaaattata agtgtaaccc tccatgttaa tttgtaaatc accagaagtt
    19741 atataaatta tttctaatga gttatgccaa tgatttgcta cataactacc actatcatca
    19801 aatagtttga aattaacatc taaattatca ataggttcaa ttatttcatg tgaaaaatta
    19861 tttctgttca taataatatc ctccttataa ttttaaatta taaatagtaa atttataatg
    19921 ttcaatatta aaaagataat atagactaat aaattagata ataaacatac ttaagaaaac
    19981 ggataaaatc aaatataata actgtatatt aaaataactt aaaaaaatta ttttattata
    20041 agtgcaaaat atacctattt aaataagata agaggggagg attttatgtg tatataaaag
    20101 gtgtaaattt aggaggttgg ttagttttag aaaaatggat gacctcaagt ttatttgaag
    20161 gcacagaagc tgaagatgaa tactatttac caagacagct ttcaagagag gcatatgaat
    20221 ctagaattaa gactcatcgt agtgaataca tcacagagag agattttgca acgattaaat
    20281 ctatgggatt taattcagtt cgtataccag taccatactt tatttttgga gattgtgaac
    20341 cattcatagg atgtgttaaa gaacttgata aagcatttgc ttgggcagat aagtatgggc
    20401 ttagtatatt gatagactta catacagttc caggaagcca aaatggattt gataatggag
    20461 gaatatcagg tatatgtagc tggtcacaaa atccagaata tgtagcgttt acattaaatg
    20521 tattagaaag acttgcaaaa cgttatggga tgagacatga attgtatgga atccaaattt
    20581 taaatgagcc tataacagaa agaatgtgga acataatgaa tgttccaaat cggtttaagg
    20641 ctgtagataa ggagatggca agggggagta aacctaattc attagagttt ttacgtgatt
    20701 tttatataaa agcatataag gtaatgcgtc cttatatgag agaggaaaac gttatagtgt
    20761 ttcatgatgc atttgaatta aaagcatgga aagactttat gagagaggaa gaatttaaaa
    20821 atattgttct agatacacac caatatttga tgttagctga atcagatgga tgtgaacaaa
    20881 gtattgatag ctatctcaaa tatattagag aaaattatgc taaagatatt ttacaaatgc
    20941 aaaaatattt tcctgttata tgtggggagt ggagcttatt taattcatat gcttgtggta
    21001 tagatacaaa tggaggtcaa tcacctctaa atgggattga atcaaatata gataaattat
    21061 caaaagacga taaaagagaa ttatatagga agatagcaaa agcacagctt gatgcatgga
    21121 gaaatggaag tggtcactac tattggaatt ataagttatt actagataca gttaatgaag
    21181 aaggttggat aggatgggat agttgggacc taggcaaatg tgtagctcaa gaatggtatc
    21241 ctatagaata ttaaactaaa attggaggaa aagatatgat taaaaaccct atacttccag
    21301 gttttaatcc agatccttgt atttgtagaa agggagatga ttattatctt gtagtttcat
    21361 cttttgaatg gtttccaggt atacctgttt atcactctaa agacttaaaa aattgggagt
    21421 tatatactca tattttgaca gatgaaacaa aaatagattt gaagaagctt ccttcatcta
    21481 aaggaatttg ggcaccttgt ttgacttatt gtgaagaaga agatttattt tacatagttt
    21541 atggaattat gaactctatg aatgcaagat attttgatgt tgataattat ttaattacat
    21601 caaaagatat aaagggagag tggagtgaac cagtatatat acactcatca ggttttgatg
    21661 cgtctattct tcatgatgat gatggtaaaa agtggattgc atcattagac tgggagacta
    21721 gagaaggata tgaaaaacct ggtgttatat gtttagtgga atactgtaca aaaaagaaag
    21781 aaatagtagg atatccaaag agaatatggt cagggggaac tgatagaggt tgtattgaag
    21841 caccacatat aacaaagcgt ggagattact attatataat gtgtgcagaa ggtggaactg
    21901 gatatggtca tagtgtaact atgggaaggg ctaaaaatat atggagacct tatgaaaaag
    21961 attcaatgaa tccaattgta acttcaattc caggcgattt ttatgaaaga catgaccctg
    22021 accatctaaa gcctaaatac tataatccag aatcaaaact tcaaaaatct ggtcatggaa
    22081 gctatataga aacaacatca ggtgaagtat atttagttca tctaacatct agaccatttg
    22141 taccagagtt aaggtgtact ttaggtagag aaacagctat tcaaaaaatg aaatggacaa
    22201 aggataattg gcttcgaatg gaagatgaaa gtaatttggc aaaagaatac gtatcagaaa
    22261 gtaaactaga agaacattta gtttcatcta taccaagttt tgatgacttt gattcaaatg
    22321 tattaggttt acagtactat gctcctagga tttcaccatt atcatttgca gatgttaagt
    22381 ctagaccagg atatgtaagg attagaggtc aagaatcaag aacatcatta aataaagtaa
    22441 gcatattggc aagaaaatta acttcagtat atgcaagaat aaccactaag atggagtttt
    22501 acccagaggt acatcagcat agtgcgggtt tgataatgta ttatgataat atgaattata
    22561 taaatttaag aaagtattat agtgaaacat tgggtcaaag tgcactatca ataatacatc
    22621 ttgaaaatgg agagaagacg gaatttttaa atactaggat accaataaaa gatataccaa
    22681 tatatcttcg tctgtatata caaggtcgta agtcatattt tgaatggagt tatgatgaaa
    22741 aaaactacca aagaatagga aaggtatttg atacaactaa gttttcagat gagtactgta
    22801 aatatggaga atttacaggt acgtttatag gattaacttg tgcagatcgt gtaaagcata
    22861 aacactatgc tgattttgat ttttttgaat atatagcaga tgaatcaaaa gatgtcgatt
    22921 aataaaatca ttactaaaat tttcagagca aaggtaaatc ttatgctctg aaataagaaa
    22981 cattagaagg caaatcttac aaaaaggagt atggtattat gaatacagaa gttaatgtta
    23041 aagcaactac gattagatat gaaaagattt cattttttga aagaatttct tatggttgtg
    23101 gggatttggg gtgcaatatc atatactcag ctatgtcagc atttttgctg ttttattata
    23161 ctaattatgc agatgttagt gcagcagctg taggtagtat tatgcttgta tctaggatac
    23221 tggatgggtt tagtgactta acaatgggaa ttatagtgga tagaactaaa tccaaatacg
    23281 gtaaggctag gccttggatt ttgagaatgg cgattccttt tgctatagca gcagtattat
    23341 tattttctgt tccatcaaat cttggtatca cttctaaatt aatttatatt tttattacat
    23401 ataacttagt ttctactgtt atttatacag caatcaatgt accctatgca actctaaatt
    23461 cacttataac tcaaaaccag tatgaaagag gagtattaag tatatttaga atgatattag
    23521 ccacttgtgg taccttacta ataaatggac ttacactacc tctagttgaa tactttggaa
    23581 ataatttatc agcatggact aaaacattct ttgtatttgg aatagcatct ataatggtat
    23641 tttttataac atttactgga accaaggaaa gagtaaaagc agttaagcaa gataggaatg
    23701 aagtaatacc atttaaaata ggtattaaat ctttatttag aaataagtac tggatacaaa
    23761 taacattatg tttagtttgc atatttattg tatttgcgat aaatggtggt tcatccgtat
    23821 attatgcaaa gtttattttg ggagatgaaa aattatttgg tcctataaat atggtttcaa
    23881 atatatccca aattatagct atgtttatgg ttgctccttt tataaaaaaa tttggaaaaa
    23941 gaaatgtatt aatagtaggt tcaataatat taatatcgtc aaatgttatg tttataatag
    24001 ttggacaaaa ctatatagga gtaatatttg caagtgctat aaagggaata ggaagtgctg
    24061 gaatagcatc aacaatgttt gctattgttt cagatactat tgaatatgga gaatggaaga
    24121 ctggatatag aactgagggg cttataaata gtgcatctag ttttgggttt aaagtgggaa
    24181 atggattagg ttcagcaata ttaggtgcag tattatcaat tggtggttat gtaggaacat
    24241 cagctactca aagtgattta gctatagtat caataaaagt atgttttata tacctaccta
    24301 tatttataac aatattacaa attatcataa tgttttttta taagcttgat aaagaatata
    24361 gtactatact taatgaatta aatactaaat aatgaaaaag tttcttataa agtcttaagt
    24421 ttaattaagg tctattgtaa atgttcccta taaaaactat tatatattta tgattattga
    24481 agaattttta gagaagcgaa taataaaaat ataagaagac tttaaatgat gaaatggttg
    24541 gtcttttaga aatgatttaa taagttattt ttatttaaag cattataagt ggacaattaa
    24601 tttttaattt atggagatga tatttaacaa ttagaagtaa tatataatat gcgctaagaa
    24661 gcaatttttc aactatttat gaaggtggtg gtacaagaaa agtatcacct tttttttgtt
    24721 atacaaaaaa acagttgact ttttatatga accccttcta taatgttact gaaattaagt
    24781 aaaatgattg aacaaatgta aagataattg aaaagcttga ttttggagga aatcaaatga
    24841 aaaaaattgg agacttaaga ttaatgatga agtgttgttc actttattac gaagataatt
    24901 tgaatcaaca ggaaatagca aatcaattgg gaatatcaag accaacaata tcaagaatat
    24961 taaaagaagc ttttgaacaa ggaatagtaa aaatacagat agttgatgtt ttgaaaaatg
    25021 attaccaaaa aatagagaga agtttggaga gaaaatataa attaaaagaa gtaatagtag
    25081 tagatgataa acaagatgca ctaacacaaa aacaagaact agcaagagct gtatctgaat
    25141 atttaactag agtagtaaag gaaaatgata taataggtgt ttcaatagga acaacactaa
    25201 aagaaatacc aagatatgtg gaaaaaagta actgtaaaaa tgttacattt atacctctat
    25261 taggagggat tggagacaat gaaatagata ttcatgcaaa tcaaatagca gtaagtctag
    25321 cgagggcttt tggaggtgat tttaaattat tacatgctcc agctgttatg tctgacttgt
    25381 ctacaaaaga gaaactttgc aaagacgaaa aaattaaaga agtactagat ttaatagata
    25441 aaacaactat agcaattgtg ggtataggaa atcctatgag tttaaactca acaataatgg
    25501 cttctggata catgaatgaa gcagatatag aagatttaaa aaaatacaac tcaataggtg
    25561 caatttgttt acaagccttt gataaagaag gaaaaacttc tatacttgaa tttaatcaaa
    25621 gagtattagg agtgaaactg gaagatttaa aaaagataaa aagaacaata ggtgtcgctt
    25681 caggagatga aaaaatagag gcaataaagg catcattaaa agcgaaattt ataaatagtt
    25741 tagcaattaa tcacagttta gcacttaaat tattagaaga ttgtgactaa tagaaagata
    25801 gataaaagtt aacaggaggg aatgtatatg tcaatatcaa aagaaacatt gcttgaaatg
    25861 tataagagaa tgaatcaggc tagaaaattt gaagagaaag ttagttggtt ttttgcaaga
    25921 ggtatggttc atggaacaac tcacttatct gtaggtcaag aagcgtcaag tgtggcggct
    25981 gtaatggctt tagaaaaagg agatttagta tcattaactc atagaggaca tagtcaattt
    26041 ataggaatgg gaatagacct aaataaaatg atggctgaac ttatgggtaa agaaactgga
    26101 ttttgtaagg gaaaaggagg ctcaatgcat atagcagata ttgagtcagg taacttagga
    26161 gcaaatggag ttgtaggtgg aggtcttaca atagctccag gagctgcact tacacaacag
    26221 tataaaaaaa caggcaaaat agttttatgt agttttggtg atggagcatc aaatgaaggt
    26281 acttttcatg aaggaataaa tttatcttca atatggaaat tgccaataat attttactgt
    26341 gagaataatt tatacggtat gtcaacaagc ataaaacgtc atatgaatat agaaagtatt
    26401 gccactagag cagcttctta tggaatagaa ggaatatcaa tagatggata taacccaata
    26461 gaagtatacg aaacagtaca aaaagctgct gagaagtgta gaagaggaga aggacctgta
    26521 ttaattgaaa gtagaactta tagatggtta ggtcattcaa aatcagatgc aaatgtatat
    26581 agaacaaaag aagaaataga atcatggaaa gcaaaagacc ctattgaatt tttaaaaaat
    26641 tatcttatag aaaataatct atctaatgaa gatgaattag ataagattca agaatttgca
    26701 aagcaatcaa tagaagatgc agtagagttt gctcaaaata gcccaaatcc aaaaatagag
    26761 tctttattag aggatgtata tgcagactaa gaatggtaaa ggaggaaaat aaaaatgagt
    26821 acaagggaat taacatatgc acaagcaata aaggaagcaa tgtcagaaga aatgagaaga
    26881 gatgaaaatg taatatttat gggagaagat ataggaatat atggaggggc atttggtgta
    26941 tcagttggta tgatagatga atttggacca gaaagagtaa gggatactcc tatatcagaa
    27001 gcagctatag caggagcggc agcaggtgca gcagcaactg gtttaagacc tattatggaa
    27061 gtaatgttta tggactttgt aacaatttct atggatgcaa ttgtaaatca agcggcaaaa
    27121 atgagatata tgtttggagg aaaagcacaa gttccaatgg ttgttagatg tccaggtggt
    27181 tctggaactg gttcagcaga gcaacattca caaagtttag aagcttggtt ttgtcatgta
    27241 ccaggagtaa aagtagttgc accttctaca ccagcagatg ctaagggatt gttgaaagca
    27301 gctataagag ataataatcc agtcatattt gttgagaata aattgttata cagaaaaaaa
    27361 ggttttgtgc cagaagatga ttatgtaatt gaaattggaa aggcagatat taaaagagag
    27421 ggtactgatg ttacagtaat tacttatgga agaatgttac aaagtgttga agaagcagca
    27481 gagactctat caaaagaaaa tataaatgtt gaaattatag atttaagaac tttatatcca
    27541 ttagataaag agactatagt aaagagtgta tgtaaaactg ggagagtttt aatttgccat
    27601 gaagcagcta agactggtgg gctaggtgga gaaatatcag ccctgataac agaaagtgaa
    27661 tcatttgatt atttagatgc tccagtaaaa agaatttgtg gaaaagatgt gccaatacca
    27721 tataatccag agttagaaaa agcagttgtc ccaagagttg atgaaataga agaagcaata
    27781 aaatctttaa ttgttagata aggagggata gatatggtgg caaataaaat aaaagccaca
    27841 ccagcagcta gaagtcaggc aagaaaagac aatataaaat tagataggct gattggaagt
    27901 ggagaaaatg gaaggattca tttagtagat gtgttaaatt atttaaaaga taataaagca
    27961 aatactactc ctttagctag aagaatagca gaagatttaa atatagattt agaaactatt
    28021 gtaggtactg gatatagtgg aaagataaga aagtgtgatg tggaaaaatt aactgcaaaa
    28081 gaaactattg tatcaaataa tacatctaaa tatagtgaga aaaaagagct gaaaattgaa
    28141 aatgaaaatt caagcatgtt taacacagta gaaggaatat ttgaaaagcc aaatccaatg
    28201 agagctactg tagcaaaacg aatgtcagaa agttatttta gtgctcctgt atttacattc
    28261 aatatagaag tagatgctac agaattgaag gtacttagag caaagttaat cgacacagta
    28321 aaagaatcaa ctggagtaaa attaactatg acagatttaa tagtaatggc agtatctaaa
    28381 atacttccaa atcatcaagc cttaaattca gcatggacag atgagggtat atttagatat
    28441 aaagatgtaa atatagctat tgcagttggt ttagatgaag gcttatatgt tccggtagta
    28501 aaaaatgcaa acaaaaagtc tttaaaagaa atagcaaaag aaagcaaaga acttgcggaa
    28561 aaagtaaaga cagggaaact tatgccagca gaccaagaag gtaatacatt tacaataagt
    28621 aatgttggaa tgtatggtat aactacattt acacctataa taaatatgcc ttcaagtgca
    28681 atcttagggg taggtgctac acaagataag tttgttccag taaatggaga ggctaaaata
    28741 aaacctataa tgaacttatc attaacatca gaccatagag taatagatgg aacagtagct
    28801 gcaaaattct taaaagattt aaaagaattg ttagaaaatc ctttatcaat gcttgtatag
    28861 gttttgatat ttcgttactg atataaatag tttgaataga ttatattatt ataattgttt
    28921 cagtaaattt aaagctttta tatattaaga attattttta acagtaacta tatgtgaata
    28981 tgatttgctt aattaaaata tatgaaaata aataggagga gagcctatgt cagtagaagt
    29041 aataatgcca aaagcaggag tagccatgga agaaggtact atagtatctt ggctaaagca
    29101 agaaggcgaa gaagtaaaga ttggagaacc tatactagaa ataacaacag ataaagttaa
    29161 tatggagata gagtcagaag gagaaggtac acttgctgta atcatacata aagaggaagg
    29221 tgaagtatta ccagtattta cagtaatagg tgtaatagca gaaaaagggg aaaatcaaga
    29281 ggaagtaaaa gctaaatatt tatctggaaa tgtttcaaaa gaagatatag ttgaagagaa
    29341 tcaaaatata gaagttaaag aagaaaaaat aaacaaaaaa gagtgtaatc atgattatga
    29401 tgtagtggta ataggaggag gacctggggg atatttatca gcattaaaag cagctctttt
    29461 aggtggaaga gttgctttag ttgaagaaaa tatactagga ggtacttgct taaatagagg
    29521 ttgtatccct acaaagactt atataaaaac agcagaaata ttagaagaaa ttgaccaatt
    29581 atcaaagaga ggtgtaaaag taactgtaga taaagaacag gacattaaga aggccataaa
    29641 atataaaaat agagtagtta aaaaacttac agctggtgtt ggcggattat taaaaagtag
    29701 agatgtagat gtgtttaatc ttaaagctag tgttaaagaa gagcataaag taattttatc
    29761 agatggaaaa gttttagata cagaaaatat aataattgct acaggttcca aagtaaggat
    29821 attacctata aaaggaatag aatcaaattt aataataact agtacagaag cattagattt
    29881 ggaaacagtg ccagaagaat tagtaataat tggtggtgga gtgattggtt gtgaatttgc
    29941 agagatattc aattcaagag gttctaaagt aactatagta gaaatggaag atagagtaat
    30001 cccaagaatg gataaagagt taagcgaatc tttaaaatat tctcttagta aaaaaggtat
    30061 aaatgtatta actaaaaaga aagtttctga atttaaagaa gaaggaaata acatattagt
    30121 gtgcattgaa ggtgaagtgc caataaaagc agatttatgt ctatatgcta taggaagaga
    30181 agctaatctt tctggcatag aggacttaga tattaaaata gataaaggtt caatagttgt
    30241 aaatagtaaa atggaaacaa gtataccaag catatatgca gtaggtgatg ttactggagg
    30301 tgtaatgtta gctcatgctg cttttaaaat gggagaggta gcagcttcaa atgctctagg
    30361 tgtgaataaa gaagttgact taggtgcatt acctagttgt gtttatacaa ttccagaagt
    30421 agcatcagtt ggtattacag aagaggatgc tagaaaaaaa tataatgtaa aagttggtaa
    30481 gtttaatttt gctggaaatg gaagagcttt agcttctggt caagaacaag gatatgtgaa
    30541 agtagtagca gatgctaaat atggagaaat tttaggtata catatgtttg gatgtggtgt
    30601 agcagaactt ataaatcatg cagcatcatt taaagcatta gagataccta ctgatgaagc
    30661 aagtgagttg atatttggtc atccatgtac ttcagaagct ttaatggaag ctttggcaga
    30721 tgtaaatgga gaatgtttac acttacctaa aaaataaatc taaacataaa ttattaattt
    30781 aagtctatta ttaatattaa tttatatcat aaaattttaa aacacttact tagccatacc
    30841 ccttattatg caaataattt atttgtataa taaggggtat tttttatgga aaaatataga
    30901 atatagaatc cttgtagttt ttgttgtaca aaaaagatag taatataaaa taacattatc
    30961 attttagaat gatttcaatt gtaattagga aaagtgattt ttttgttttt aaaaaaagta
    31021 ttatttgtaa aatataaaaa aaaatttctt aatatttgaa taaaagaata gcttaattta
    31081 aatgttatta ctttataaaa aaataataag tacaaaaaaa acaatatatg gcatataagt
    31141 tgctatataa ataataagga gggaacaatt ataaatgagg caaagaataa aaaacttaat
    31201 tgaaaatgaa gataagaaaa atcctttaac agatgaagcg atttcaagta ggttaaatat
    31261 tcgaagagaa gatgttacct ttttgagaaa tgagttaaaa atagaagatt caagacaaag
    31321 aagaaaagtt gttttaatta aagctataaa agatatttta aaagaagaaa aaactataaa
    31381 taaaaatgat ataacaagaa gattaaacag cattgggttt acagtatcaa gatttacagt
    31441 catacaatac ttaaaagaga ttcaagattc tggtgaccta aaacttgata aagagagtga
    31501 tgataaaaaa gaagaaataa tcaataatag agaaaataaa gatatagcat ttgataaact
    31561 cataggtagt agtggtagct taagtacaat tataaaacta gccaaagcag caattcttta
    31621 tccacctcat ggtcttcata ctattattat ggggccaact ggtgttggaa agagtgagtt
    31681 agcagagtgt atgtataaat ttgcagtaga atcatccaga ttccctaaga atgcaccatt
    31741 tatagttttt aatgcagcag attattcaga gaatccacag cttttgctat cacagttatt
    31801 tggacacgtt aaaggtgctt ttacaggagc tgatgagaac aaagaaggat tagtatcaaa
    31861 ggcagatgga ggaatattgt ttatagatga aatacataga ttacctcatg aaggtcaaga
    31921 aatactattt caactgattg ataaaggtat ggtcagaaag ttaggagaaa caagactaac
    31981 acataaaata gatgtaatga ttatttcagc aacttctgag ccaatagatt ctcatttact
    32041 taatacattt aaaagacgta tacctgtaac aattgaaata ccagaattag ttgcaagacc
    32101 attaaatgag aggtttgaca ttataaataa tttcttctta atagaagctc aaagaatggg
    32161 agcaaacata catataaagt cagatgtatt aaaagctctt atgctttacg attgtatagg
    32221 taatgtaggt caacttagaa gtgatattca agtagcttgt gctaggggac tattaaacca
    32281 acttacaaac aaactaaaag aagtaaatat aagcatatca gatgtacctg gatatgtaaa
    32341 acaaggtctt ataaaaatca gaaattgtag aggtaaaata gaaaattatg tagatgggga
    32401 tttaattata gattcaaatc ttcaaggtga gatagaaaag aaaaatgaag atatatatac
    32461 ttttccagat gaaatataca aacttactga aagaagacat attgatttat tggaacaagg
    32521 tttagatttt gatgttataa atagaatcat tggaggagaa ttagaaagtt gcattcaaaa
    32581 atacataaaa caagttaaaa aagtttctat tagtaacaat cttccagata taagtccaat
    32641 tgttggaaaa tatatcgtag agctaactta tgaagtaatc aaaatagcat cacaatacct
    32701 aagttcacta gaaccgaatc tacatttatg tttagcagtt cacctaaaag cagcttttga
    32761 gagattaaaa gaaggaaaag taatatcaaa tgctcatttg aaagaaataa taggaaatta
    32821 tccactagaa tattctgtag cagaaaaggt agctcaatat ttaaaggaaa gatataatat
    32881 aaacttacca aaagaagaaa taggtataat agcaatatat tttaaaatga gtagtagaag
    32941 agatatgtct gaacaaaaaa agataggtgt acttcttatg gctcacggaa gagtagcatc
    33001 ttctgtatgt gaggttacaa ataaactatt aggaattaat cacgcaaggt atttagatat
    33061 gccatttgag aagaagccgg aagaaatgat tgaagaagct actacaataa taaaagatat
    33121 tgatgaaggt agaggtgtga ttatattagt agatatgggt tcactttcat attttggaga
    33181 tattatttct ggaaagactg gaattaatat aaggacaata tctagatttg atacattgct
    33241 ttctatagag gttatacgaa gagcagtttt accagattta acaatagacg agatagttga
    33301 tgaagttaaa ggtatagagc cacaagtaaa agaaaaggtt agtaaatgta acaatacaaa
    33361 agtagatttt agaaaaccta taattttaac attatgtatt actggattag ggggagcttg
    33421 taagataaaa aaaatcctag aggaaaatat taaaagtata actgaaaagg ttgatataga
    33481 acctataggt atgattgaat atccaagtct tgatttagag ataaaacaaa taagcaatga
    33541 taaaaatgta atcgccatag ttggaacaat tgaccctcag atagcaaata tccctttttt
    33601 tagtctagta gacataaatg ataaagcaaa gttaaatcaa ataaataacc taattgatac
    33661 aaatcaaatt ggtgaaacaa ataaaaaata tgaattatca gatttaatac ataaagaaga
    33721 tatatttgtg gatttacagg ttaaatcaaa agaagaagtt ctaaaatata tgagtaaaaa
    33781 acttagagag aaaggttatg tgacaaaaaa tttctataaa aaagtagtgg aaagagataa
    33841 cttatttcca actgaattat cagatgaaat agcaatacct cacacagatg gaatagatgt
    33901 aattaggcca gctataagta tagccatctt aaagaagcct attgtgtgga gtaaaagtaa
    33961 agtaaaaata atacttttat tagctgtaga ccaaaagtgt tttaatccat taagcactct
    34021 actctcattt atagaaacag atgaatttaa gaagataaaa aacattaaag atagagattt
    34081 tattagggag atgatattag atggagtcaa tgaaaataat tagtagcaat ttaattttta
    34141 aaaatattga agtgtctaac aatgaagatg cattaaagtt tttgggacaa cgtttgtttg
    34201 acgaacagta tgtaaaagaa agctacatac aagctgttgt agcaagagaa aaaaagtatg
    34261 ctacaggatt accaacagaa atatacggag tggcaatacc acatacagat atagtacatg
    34321 taaatgagcc aggaatagca attggaatac tgaataaacc agtaaaattt ataatgatgg
    34381 gtacagacga tactgaaatt gatgtaaaag ttgtatttat gttagcagtg aaagagccac
    34441 aagaacaatt gcaactatta gaaaaactta tgactatatt tcaagataag aatatactaa
    34501 ataatattgt tgacttaagt gaagaaagtg tgagtgattt attaaactct aaattgaaaa
    34561 attaaacatg taaagtatat taaaaatgta aaattaaaca tgcaaagtat gttaaaaaat
    34621 ataaaaagat tattaaagat ttctaactat agatatcttt aaaataaaat aatttcaatg
    34681 ggggtgacta atgtgactaa aaagatatta gttgcatgtg gaacaggagt atgtacttca
    34741 acaattgcta taaacaaatt aaagaaagca cttcaagaca ttggtaaatt ggatatggtt
    34801 aatattacac aatgtaaagt agtagaagtt gcatcaaaag cacctgatta tgatttaata
    34861 atttgtacta cacaagtatc tagtagtata aaaacaccag tgataaatgg attacctttt
    34921 ttaactggtg tcggaatgga taaattaatc aatgatgtat tagaagagtt agaattataa
    34981 ttaaaaaaat taaggaacat ggtctctaaa atcataagtt ttagagactt aaaattaaat
    35041 aatggagggt ctttatatgg agatattaaa tttcattgtt ggtctaggtg cacaagtaat
    35101 gatgccaata ataatatgta tttttggttt gatattaggt acaaaactag gaaaatcttt
    35161 aagagctggt ttaactgtgg gagttgggtt tataggtctt aacactatta tagctttgct
    35221 aacagataat ttaggtccag ctacacaaca aatggttaag aatttagggc taagtttatc
    35281 aataatagat gtaggatggc cagcagcatc agctatagct tttgcatcaa cagtaggggc
    35341 tttaattatt ccaataggtc ttgtggtaaa tatagttatg ctaattacta atactactca
    35401 aactgttgat gtagacatat gggattactg gcattttgct tttacaggag ctttagtggc
    35461 aggggctact caaagtgtaa tgtggggagt atttgcagca gtagcaaata tggtaattgt
    35521 attggtaatg gcagatttaa ctgctccagg tatagaggaa tatttaggta tgccaggtat
    35581 atctcttcct catggattta cacaggcatt tgttccaatt gctatagtag taaataaatt
    35641 attagaccta ataccaggta taaataagat tgagataaat gctgatacat tgcagaaaaa
    35701 atttggatta tttggagaac ctttaataat ggggtctgta ataggtgtaa taattggtat
    35761 tgctgcgaaa tatgatataa aaggaatatt acaattaggt gtaactatgg gagctgtatt
    35821 aatattaatt ccaaagatgg cagcattatt aatggaagga ttattaccag tatcagaagc
    35881 tgcacaggaa tttattgaga agagatttaa aaacagaggc aagatttata taggcttaga
    35941 ttcagcagta ggaataggtc atcctgttac attatcagtt gcactagtgt tggttccttt
    36001 gactatactt atagcagcta tattgccagg aaataaagtt ttaccatttg cagatttagc
    36061 agtaattcca tttgcacttg tattaatcgt accaattaca aagggaaatg tgtttagaac
    36121 attaataata ggaataatta taattacttc tggattatta atcgcaacta acttagctcc
    36181 attatttacc caaatggctt taaatgctag ctttaaaatg cctgaaggag caactatgat
    36241 ttcaagtatt tgtgatggtg cgaatccatt aagttgggta tttgtaaaag ttatgaacta
    36301 taaagttatt ggaggagtag tttttggagt tatagcttta ggaatggcta tttacaatag
    36361 gaatagaata ataaatgaaa ataaaaagct atctatagaa gaataaggtt aaaacaattt
    36421 tattaaggag tgtataggtt atgaaaaaat ataaatatga ttctaaaagg tacttactca
    36481 gtgttacaat accaggattt tttatgattt taatattgat ttatgcactg tttaataact
    36541 atataaattt taatttgaat atatatagtt tgttaataat tgtctgtact tatggtatat
    36601 tcaatacttt tatatcatca agtaatccta aaaaaattat tattgacagc aaatgtatac
    36661 attttacctc atttatgact acacataagt atgaaattaa agatatagaa aagataagaa
    36721 taagagaatt ttataataaa aaaatttatc taaaaattaa tgatggagac ctttttaaag
    36781 gtaggtattg gataagaaca aatatgttta ataatagtat agcattatat agttatttca
    36841 ttgagttgga agagtgctta tatccagatt cactaagatt tagaaataaa aaatttgaga
    36901 ataagaatat ataaaaataa aaaattgaat tgaagcctaa cttaatcttt tttgataaga
    36961 tataagtttg aactttatac taaattttta gaattttcaa tcaagacaat aacataatag
    37021 ctaagcaatt agaacacaac taagatgtat aaggcatgta tatgatgaat gggaggattt
    37081 aattaatgtt attagagaaa ttaagaaaag aagtattaca agcatcttta gaccttttaa
    37141 actataattt agtgacatta acaggaggga atgtaagtgg gagagatgaa caaactggct
    37201 atatagcaat caccccaagt ggaatggatt atagaaatct tacaccaagt gatattgtta
    37261 tagtagatgt agatggaaat attatagatg gaaaatggaa agcatcagtg gatttatcag
    37321 accacttgta tatatataag catagagaag acataaatag tataattcat acacattcta
    37381 catactcaag ttgttttgct attttaaatg aacctataga atgcgcaagt acaactcttg
    37441 caaatgaagt agggggttca gtaccagttg caaaattttc accaccaaca tttaaaaaga
    37501 tgggaaaatg tgttattgaa gcaattggtg acaaaagagc atgtctttta gcaaatcatg
    37561 gcgtaattgc agttggtcca tctgtaggac atgctcttac agccgctgta atgttagaag
    37621 attcagcaaa agtatattac ttagcaaaat caattggcac accagtgcta ctgcctgatg
    37681 aagaaattca aagagcgaga gatgtatttt ttaatgtcta tggtcaggat aaataaatta
    37741 gataaaattt taaaagtaat atgaaaatat agatattcaa tgatattaag gagatttata
    37801 atgatataat aagtttaata gttaagaagt aaaatatgaa atgtaatagt atataaattc
    37861 atttaagact aaaaataata agataaaata aaaaggagtc tgtatttcta tgtattactt
    37921 attaaacaaa agcacaaatc cttactttaa tttggcatta gaagaatatc tatttttaaa
    37981 tgataaatat aatgatgata ttataatcat atggagaaat gaagactcca tttttatagg
    38041 taaaaatcaa aatccatatc aggaagtaca tcatgatgtt attgaaaagg gagaaattcc
    38101 tattttaaga agaatatctg gagggggcac tgtttatcat gatttaggta atatcaatat
    38161 gtcattcata caaaaagata ggcaacttca tgagatagat tttttggagc atactaagtt
    38221 tatgcaaaag atgctttcaa ccttaggact agatgtatct ataactgaaa gaaaagattt
    38281 atttttaaat gggaaaaaaa tttcaggctc tgcacagtct ataaaaagaa aaaattctct
    38341 ttatcatgga actcttcttt acgattcaga tttaaataaa ttaactaaat atttaaattc
    38401 aaataaagca actgaatcaa atgcaactaa atctgtttca agtaaagtta caaatattaa
    38461 gtttttactc gaaaaagata taaattactt tttagattat tgtgttgaat atttaaaatc
    38521 taatataaag aatataaaag aacttgaatt ggatgaagaa gatattaaaa gtgtatacaa
    38581 tataggagaa gataaatata gaaagataga gtggacatat ggtaaaacgc cgaaatttca
    38641 agtagtgcta ccatttaata atgaaagtaa aataaatata catgttaaca gatggaaagt
    38701 atcaaaattt tttatttctt atgatgataa tgtaattaat atggataagt tgttagattt
    38761 gaatttcttt aaagaagaaa taaaagagag tattttagaa aattatccac attacataga
    38821 tttaatcaat ttaatatttt aatataaaac ctctaatttg ataaaattgt cttatatcaa
    38881 actagaggtt tttaatattc ttgcatatta acaaccatta caaaattgta aaattaaaaa
    38941 caacactatt gaaaaatcaa tatatattgt aataaatata tgtgtttttc attagcaaat
    39001 agacattaac tatttataca actgaaaatt taatatataa ttaatcagat ggttaaaata
    39061 aaaatattaa aagttttaat aaatgatggt taaaaataaa atacgaggtg ataccatgta
    39121 cagtgttata attgttgcag cgggaagcgg aaggagaatg aacttagata taaacaaaca
    39181 gttcataaaa ttaagagaaa aagaaattat tgctcataca attcaagttt tttatgaaaa
    39241 tataaatata gatgaaatag tggtatgtat aaaaaaagaa gaagaggatt tttttaaaga
    39301 aaatataata aataagtata actttaaaaa tataaaaata gcatatggcg gaaaagaaag
    39361 acaggactca atatataatg gtttaaaaaa attagatgaa aattgtgata tagtacttat
    39421 ccatgatgga gcaagaccat ttgtcgacca tagaataatc aacgaatcta taaaggtagc
    39481 taaagaaaaa aaggctgtgg ttgtaggtgt tccagtaagt gatactataa agatagtgtc
    39541 agatggaaca gtacaagaaa ctccagaaag aaatttgttg tgggcagcac aaacccctca
    39601 aacctttgaa tataatctca taatagatgc ttatgagcaa gcatataaga acaattatta
    39661 tggtactgat gattcaatgt tggtagaaaa tataggtcaa agtgtcacta tggtaatggg
    39721 ttcttatgaa aacataaaaa taactagtcc agaagattta aatatagcag aacaaatatt
    39781 aaatatggaa aaaagagatg aagttaacag tagaaggaga attatatgag aataggatta
    39841 ggatatgatg tacacaaatt aacagagaat agaaaactta taatcggtgg tgtagagata
    39901 ccacacgata aaggtttgtt gggtcattct gatgctgatg tattgataca tgcaataatg
    39961 gattctattt taggtgctct agcattagga gatattggga agcatttccc agatacagat
    40021 gaagaatata agggagcaga tagtatgaaa ttattagaac atgtgtataa tctaataaca
    40081 agtaaaggat ataaaattgg taatatagat agtactataa ttgctcaaag ccctaagatg
    40141 gctccatata ttgagagtat gagaagtaat atatcaaaag ttttaaacac agacattgat
    40201 aatataaaca taaaggcaac aacagaagaa ggtcttggtt ttacaggagc aaaacaggga
    40261 atagcttcac aaagtatttg tttattattg ttgacaagtc agaataatta atatattatt
    40321 agtaataagt ttaatggata tcaagtaata ggcctatata gaatatctat aatgtatgaa
    40381 tttaagtgaa attaatataa atataaaatt agctatgata aagaaatagt aaaatgatga
    40441 aatcttcaca gagagaaaac ggtggtgaga gttttcaaga ggaagtcttt gaacctgtct
    40501 tttagcttaa aggtataaaa atctttacgg taggaaccgt tatattccca aaagagagct
    40561 attcatatag ctaactagag tggtaccgcg gaaattaaac ctttcgtctc tatacttgta
    40621 tagagatgag aggtttttta tattttcagg aagttaatat tcaggaggaa tctattaatg
    40681 aaaatgtcaa aaatgtttat gccgacatta aaagaaatcc cagcagatgc tgagattaca
    40741 agccatcaat taatggttag gtcaggcatg ataaaaaaaa tgacttcagg tgtttataac
    40801 caattaccaa tggggttaag agtgttcaaa aaaattgaac aaataattag agaagaatta
    40861 aataaaaaag attgtcaaga aatactttgt gcagccttac ttccttctga attatggaaa
    40921 gagtctggaa ggtggactgc tatgggtgaa gaaatgttta gactaaaaga cagaacagaa
    40981 agagagtact gtcttgggcc aacacatgaa gaagcattca ctgatataat aagacaagaa
    41041 attacttcat ataaacaatt gccactgaac ttgtaccaaa tacaagtaaa atatagagac
    41101 gagagaagac caagatttgg tgttatgaga actaagactt ttacaatgaa ggatgcatat
    41161 agttttgatg tagatgataa aggtttagat aagtcatatc aagatatgtt tgatgcatat
    41221 gtaagtatat ttgatagatg tggattggag aatagccctg tacaggcaga ttcaggagct
    41281 ataggaggtt ctacatcagc cgaatttatg gttaagtcag aagttggtga agatgaagtt
    41341 gtattttgta gtggatgtga ttatgcagcc aatgtagaaa gagcagaatc ttgtaatcta
    41401 gcatcacaaa aagaagaaat gaaagaatta gaagaggttc atacaccagg agcagctaca
    41461 ataaaagagt tagaagaatt tttaaaaact tctccagata agtttgctaa aactttagta
    41521 tatgaggcag atggaaaaac agttgtagtc gttgtaagag gagatagaga agttaatgaa
    41581 atcaaagtat ctaatgctat aggttctgtt atagaatttg ctcttgctac agatgatgta
    41641 gtgagaaaag taactaatgc agaagtagga tttgcaggtc caataggtat aaatgctgac
    41701 tatgtattta tagataaaga aattgttgaa caaagaaaca tagttgttgg ggctaataaa
    41761 actgagtacc atataaaaaa tgctaactat ggaagagatt ttgaaggaat agttggagat
    41821 tttagaaatg ttcaagaagg cgaccagtgt atagtatgtg gtaagccact tgaaatagct
    41881 agaggtgttg aagtaggaca tatatttaaa ctaggaacta agtactcaga atctatgaat
    41941 gcaaacttca tagacaaaga tggaaaatca aagcctatag taatgggatg ttatggaata
    42001 ggtgttgaaa gaacagcagc agctataatt gaacaacata atgatgagaa aggtataata
    42061 tggcctttgt cagtagctcc ataccatgtt gtgatagttc cagcaaatat gaaaaatgaa
    42121 gaacaaatat caatagctga aaatatatat aatgatttgc aagctatggg tgtagaagtt
    42181 ttattagatg acagagatga aagaataggt gtcaaattca atgattcaga attaatagga
    42241 atacctatga ggattacagt aggtaaaaat attaatgaag gtaaagtaga atttaaactt
    42301 agacataaag aagataaaga gataattgac atagaagaaa taaatgaaaa agtaaaggca
    42361 gagtttatca ggaataatgt taggttagga taataactta aataagatat tgtatagata
    42421 atcaaagttg tactttatag acaccatttt atctatatat aaggatataa aatggtgttt
    42481 ttttataaaa caaataaatg aggaggtaat tgaaatggca aaaaatgaaa aacaatttgt
    42541 tgaagaaata acaaagatgg aagatgattt tccacaatgg tacacagatg taataactaa
    42601 gactgactta gttgattatg caccagtaaa aggttttatg gttgtaaagc catatggata
    42661 tgcattatgg gaaaagatgc aagaatttat ggataaaaaa tttaaagaaa ctggacataa
    42721 aaactgttat tttccattat taataccaga gagtttatta aacaaagaag cagaacacgt
    42781 tgaaggtttt gctccagaag ttgcatgggt aacacatgga ggaaataaaa aattagaaga
    42841 aagattatgt gtaagaccta cttcagagac tataatatgt acaatgtatg cgaaatggtt
    42901 aaaatcatat agagaattac catatcttta taatcaatgg tgctcagttg ttagatggga
    42961 aaaatcaact agacctttct taagaacatc tgagttttta tggcaagaag gtcatacatt
    43021 acatgaaaca gcagaagaag cacaagaaga aacaatacaa caattagaag tatataaagc
    43081 gttatgtgaa gaattacttg caatgccagt tgtagctggt caaaaaagtg aaagtgagaa
    43141 atttgcaggt ggtgaaagaa catatactat agaagctatg atgcatgatg gtaaagcatt
    43201 acaatcaggg acaagtcact tcctaggtca acactttact aaggcttttg atattacttt
    43261 tgcagataga gaaggaaatt tagctaatcc ataccataca tcttggggag catctacaag
    43321 acttataggt ggacttataa tgactcatag tgataacaga ggtttagtat taccaccaag
    43381 agtagctcca attcaagttg ttatagttcc tatagctgct aaaaaaggaa atgtaatgga
    43441 gactgttgat aaaatatatg ctgatttaaa aactaaggga gtagccgtag aagttgatga
    43501 tagagataac tatacaactg gatggaaatt taatgagtgg gaaatgaaag gtgctccagt
    43561 aagagttgaa attggaccaa aagatataga aaataatcaa gctatggtat ttagaagaga
    43621 tactttagaa aaggattcta tgcctttaga aggattagct gatgctatat gtgatttatt
    43681 tgatgttata cacaatgata tgtttgaaaa agcaagaaaa catagagaag acaatacatc
    43741 tatagttgaa aatatggatg agtttagaaa agctttagaa gaaaagccag gattcataaa
    43801 gactatgtgg tgtggagatg cagaatgtga agctaagatt aaggaagaaa caggagcaac
    43861 tataagatgc ttaccttttg aacaagaaaa cttaggtcac aagtgtgtgt actgtggaaa
    43921 agaagcagat agtatggtag taatggcaaa agcttactaa aatacattta aataaaaact
    43981 ggggtagaaa gtatttaata ctttatccca gtttttttgt tttttatgag taataaaatg
    44041 tatttgtaac tatgtcataa gataagtcat agatacttat attaaaaaga atataataga
    44101 gaactatttt taataattac atattaatga aagcaaaata tttttgttat atagattttc
    44161 aataaagcaa acaataaata taaatgaata ttagtaagga gtgcttttaa tttttagaaa
    44221 ataaatgact taaaagaaag atttatgaaa ttaaaactag gattttctga tataataaac
    44281 atgtgtattt ttaaataaaa aggatattat tattagattt gattaaaaat aaacttgcaa
    44341 aacaatgtac tagtttaata ttatagttat attgaataaa atatcaggag gaagtaaaaa
    44401 tgaatgtaag agtaaggttt gcaccaagtc caacaggatt tgtacatata ggtagtttga
    44461 gaactgcttt atataactat ttatttgcaa aaaaaatggg tggagaatat atattaagag
    44521 tggaagatac agaccaaagt agattagtag aaggtgctat agagaatatg cttaatgcta
    44581 tgaaatgggc tggtgtcaac catagtgaag gtgttatatt agatgatagt ggaaaagtag
    44641 tacaaaaagg agaatatggt ccatatattc aatctcaaag attagatata taccaagaat
    44701 atataaagca acttttagat agtggaaaag cttattattg tttctgtaca aaagaaagac
    44761 tggatgaagt aagagatgct caaagagcag caggagaaac agctaaatat gatggtcatt
    44821 gtaagaatct ttctaaagaa gaagtagaag cgaatataaa agcaggaata ccatatgtta
    44881 taagattaag attgccagag aatcatacaa ttaagtttac agacttagtt agaggagata
    44941 tggaatttaa tactaatgac ctagatgacc aagtattaat gaaaacagat ggatttccaa
    45001 cttatcattt tgcagtagtt gttgatgact atttgatgaa aattacacat gttataagag
    45061 gagaagaatg ggtatcatct actccaaaac atgtttattt atatgaagct tttggatggg
    45121 aagcacctgt atttgtgcat ttaccaaata tacttaataa agaaaagaaa aaattaagta
    45181 aaagacaagg tgatgtagct gttgaagact ttaagaaaaa aggatattta ccagagggat
    45241 tagtaaacta tgtagcatta gttggttggt ctcctgaaga taatcaagaa ttgtttacaa
    45301 tggaggaatt agaaaaagcc ttctctgtag aaagagtatc taaaagtggt ggagtatttg
    45361 atactgaaaa attaaattgg gttaatcagc actatataaa agatggtgat gatgcttatc
    45421 taacagactt agcaatacca tttttagtag aagatggatt tataacagaa gaagaagcta
    45481 ctaataaata tgatttctta aagagtatga tatcagtact taaagagaaa ttacaatatg
    45541 taaaagaaat tactgaacat gcaagtatat tttttggaga taaaatagag gtagaaactg
    45601 aagagggaag agagttctta agattagaac atatacctac tttaatagat gctttgagag
    45661 aaaaaataga aaaaacagag gtattaaatg ctgagtttgt tcaagctatg cttaaagaaa
    45721 tacaaaaaga gtacaaaata aaagggaaaa atttatttat gggctcaaga ataattttga
    45781 cagggcaaat gcatggtcca gatttaccaa aagtaatgga agttttagga aaagaaactt
    45841 gcttaaatag aatagcttat gtaaaaaata atatattata gtcataaaag tccgctaatt
    45901 tagaagcgga ctttttttgt gttagtattt ggtgaaaata tctgcttaag aaaatgaagg
    45961 tatttaaggt aataaattta atatataaaa agcaaagcaa aaatataaat aaaatatgaa
    46021 taataaacta ataaaatatt aagcatagaa gaagggaatc tattatttta gtttgattta
    46081 attattaagg gggtaattac tatgtatagt aatattgatg atgttaaaaa ggaattaaag
    46141 gagctatgct tagaatatgt tacaatttta gaaaaattaa aagatgaaaa aatgattaca
    46201 gaagaaactt ttgaaaagtg ctcttctcaa aaaaaaatat ttttagaaga acaatagagg
    46261 atggtaatag tattattatt atgtagtttg aaagatagta cgaaaaatga tagtaatact
    46321 attatttatt gcaattttca actataatat aatatataat gttaagaaga taatttataa
    46381 aaatacagtg aggtgatgag tgtgaaagtt tataatacat tgactagaac aaaagaagaa
    46441 tttgttccat tagaagaagg aaaggtaaaa atgtatgtgt gtggtccaac agtttataac
    46501 tatatacaca taggtaatgc aagaccattt ataatatttg atactctaag aaggtattta
    46561 gagtatagag gatacgatgt aacttatgta caaaacttta cagatgttga tgataagatt
    46621 ataaatagaa gtcatgagga gggaatatct cctgaagaag ttgcggctaa gtatataaaa
    46681 gaatattttg tagactgtga tgggctaggg ataaaaagag ctactgttca tcctcaggtt
    46741 acagataata tacaacagat tatagagttt ataaaagagt tggaagataa gggatatgca
    46801 tatgcagtaa atggtgatgt atattttgat acaaataaat ttgaaggtta tggaaaactt
    46861 tcaggtcaaa aacaagaaga tttagaggca ggggctagaa ttgaggttaa tgaccaaaaa
    46921 agacatccta tggactttgt tctttggaag gcaaaaaaag aaggtgagcc aggatgggat
    46981 agcccttggg gagaaggtag accaggatgg catatagaat gttctgttat gtctaagaga
    47041 tatttaggtg aaacaattga tatacatgca ggtgggcaag atttaacatt cccacatcat
    47101 gaaaatgaaa tagctcaaag tgaagctaga agtggaaaaa tattctcaaa atactggatg
    47161 cataatggat atataaatat aaatgatgaa aagatgagta aatcaaaagg taatttcttt
    47221 acagtaagag atatatcaaa attatatgat ttagagatag taagattttt catgttatca
    47281 gcacattata gaaatccagt aaactttagt gatgagatgt taaatcaagc taaagcaggt
    47341 cttgaaagac tatataatac taaagaaaaa ttagaattta cgctaagtaa tttagtagaa
    47401 tctcctttaa cagaaaaaga agtagagctt gttaaagaat tagatgactt tagacaaaaa
    47461 ttcatagatg ctatggatga tgatgttaat acagcagacg cagtaagtgt aatatttgaa
    47521 ttagctaagt taataaattc taatgtagat gaaaattctt ctttggagtt tgctaaaaaa
    47581 tgcttagatg aatttaatga acttacagga gtattaaata ttgtaaataa gaaaaaggat
    47641 actgtattag ataaagacat tgaagaattg atacaaaaaa gaactgatgc aaagaaaaat
    47701 aaagagtttc aattagctga tgatattaga caacaattac tagatatggg aattgtatta
    47761 gaagacacaa gacaaggtgt taagtggaaa aggatataaa aatggaaaaa actgaattag
    47821 ttactatgtc accattagtt ttagcatact taggtgatac agtgtatgag acatatataa
    47881 gagaatattt aattagacag aatacacaaa gaaaagttaa tgatttgcat aaactagcta
    47941 taaagtatgt aaaagctaaa gctcaggcaa ctataattca tgaaattgaa attgagttaa
    48001 ctgaagaaga gagtaaaatt tataaaaggg gaagaaatca aaagtcaaat acttctccta
    48061 agaatgcaga tattatagac tacaaacatg caactgggtt tgaggcatta gtgggatatt
    48121 tgtatttaaa taatgaaata gagagacttc aatatattat caataaagga atcaaaatta
    48181 ttgaaagaga tatgtaaata ttaaagagtg ttgtcttaat aataagtaat aaggcaacac
    48241 tttttttata actaatgtat aataaatata tagaaattag taatgagaaa ggataagaaa
    48301 gttatgaaag taaaattaat atcacataca cctgaaccag aaaaagtaat agctatggca
    48361 gctaagctat gttattcacc agttgggaca gacgaaatag aaaaagattt ctaaaatata
    48421 ttaaagagca ttcctataac aaatactatg gcggttggaa tctatgagaa gttatagata
    48481 tagaattatg taaattattt ggaaaaaaca ggtttgaaaa ttagccatgt tggtatttct
    48541 aggttactta aggaagatca aacataaata agctgagttg tcttaggtgc actatgtaca
    48601 acattagaat gtgaagttga agatttatta cttcaaacga acgatggtac taagaaaaac
    48661 aatgatgaaa tgattaatta ataataaagg taaggaggta gtatatgagt ttagcagata
    48721 aaatttttat tgatatgtgt aataatattc ttgaaaatgg agtatcatca gatggagagg
    48781 tagttagagc aaaatgggat gatggccagc ctgctcatac aataaagaag ttttgtgtag
    48841 taaataggta tgatctttca aaagaattcc caatacttac actaagacca acaaacttaa
    48901 aagcagcaat agatgaatta ctttggatat ggcaaaaaaa atctaataat ataaatgatt
    48961 tgaatagccg tatttgggat agctgggctg atgaaacagg ttcaataggg aaagcttatg
    49021 gataccaaat tggacagaaa cataaataca aagaaggaga atttgaccaa atagatagag
    49081 tgatttatga cttgaaatat aatccttata gtaggagaat tataactaat atatataatc
    49141 ataatgattt aaatgaaatg aatttatatc cttgtgcata tagtatgaca tttaatgtaa
    49201 ctggaaatag attgaatgca atattaaatc aaagatcaaa tgatattttg gtagctaata
    49261 attggaatgt aactcagtat gcaattttag ttcacatgtt agcacaaata agtgatttgg
    49321 aagtaggcga attggttcat gttatagcgg atgcacatat atatgataga catattcctc
    49381 tagttaaaga gcttattaat agagaatctt atgatgcacc aaaattaata ataaatccaa
    49441 acataaagaa tttctatgac tttagagttg aggactttac attagaaaat tataaaagtg
    49501 ggccacaaat caaaaagatt cctgtggcaa tttagaagga gttatttatg aaagttatag
    49561 tagctgtaga tttaaattgg ggaattggtt atggtggaaa gttactacag tcgattcctg
    49621 aagatatgaa attttttaaa gaaaaaactg taggtaatgt agttgtaatg gggagagaaa
    49681 cctttaaatc attaccagga aaaaaagcat taaaagatag agtgaatata gtcttgacta
    49741 gaagtaaatc ttttaatgat gatagattga ttgtttgtaa ttctatagat gaaactctta
    49801 aggaactaca aaaatatgaa aatgataaaa tttttataat aggtggagaa acagtatata
    49861 aacaattttt accttattgt aatgaactat atgtaacaaa aatacagaag acatatgagg
    49921 cggatagatt tttccctaat atagatatta tgtcaaactg ggatttgatt aaagaaagtg
    49981 aagtaaaaga atataacaat ataagatatg ttttttcaac atatataaat aatagtttat
    50041 aggtttgtat aggagagaaa tttaatttat gaaaaaggat atatttgtaa atagagtttc
    50101 taatgcttta gaaaatgata gaggcgcagt ttttgtaggt agtggtatat cgtttagttc
    50161 gactgaagtt gattggttta aattactgga gccattagta aatgaacttg atataacatt
    50221 agacaataaa agtgatgatt tacctatgat tgctcagtac atagtaaata attattcagg
    50281 aaatagaggg cctttagtaa acgaaatatc aaaaacattt aatagaaagt ttaaactaaa
    50341 caagtatcat aagtatttag caacaactaa actttcaaca atatggacaa ctaattatga
    50401 tatgttgtta gaagatgcat tttatgattt tgatacatcg gttaaagtaa gtgatgattc
    50461 tattacaagg aatagactag aatatgatgt ggaaattata aaaatgcatg gatgtatttc
    50521 tagatccgat tggaatgaaa tagttataac tcaagaagat tatgatgatt tttcaataaa
    50581 taaaccagct atatctcaaa gattaagtga agatttaata aataagtctt ttctatttat
    50641 tggatatagc tatagagatc caaatataag aaatataatg ataaatgcta gaaggctaag
    50701 taaaaaacat actcaacaac attatataat tttaaaaaag ttaaaagata gtgatagtaa
    50761 tattacgcaa gatgatgtag taagacaaga actttggtgc aatgatttaa aacgtttggg
    50821 aatttcaact ttatttatag atgaatactc agagttagag gaacttttaa gagagataag
    50881 tcaaaaatca agaggtaaaa cagtatatgt gacaggttct cataaagaaa gcaatatgaa
    50941 tgcaagaaaa ttaggaacca agctagcaaa acataaagat attactttac taagtggtca
    51001 atcatctggt attggctcag aggtagttgc tgcgtttact gaagagtgta ttaagagtaa
    51061 agaagatatt ataaatagaa tgaaaatatt tcctaatcca tattcagctg atgaaaaata
    51121 ctctgatgat attactttaa taccagattt aaagaaatgt agaactaaaa tgttgaattc
    51181 aacacaagtt gtagttgtat ttagtggagg tataggtact gaagcagaga tagatgttgc
    51241 tataaaacaa aactgtaata taattcctgt tataacatgt aaagaggata gagagaatcc
    51301 agctataaaa aaaatcttaa actatagtga taatatgaaa aatatagaaa taaaagatgc
    51361 tacctattat aataaaatag tagatgaaga tggtgttgta acaatggagg aaatttatat
    51421 atgcatatca aaaataatga attaaaacat gacattatta aattgaaaaa aagaaatgga
    51481 tttattgaag ttggaaaaga taaaaaaacg ttggtaaact gtttaattgg agcgaatgaa
    51541 ttagaggatt acaaatatga aataaaaaaa atagattgta tacttaatat atcagaaaaa
    51601 ccagatatag tttcagattt aagtactaaa agaagaaaaa taagtgaatc tatatggtat
    51661 aagatagtta aagatacacc tttcgtatct gctacactgc ccatatactt agttagtaaa
    51721 aataataata aaatagatag taatgaatta ttagatataa ttattgagca gatggaaaat
    51781 ggagttggga tgataacgat tcatccaaca gcaaataaac aaatttttga ggattctaag
    51841 aatagaatgg tacctgtcac atctagaggt ggaggtatgg taatacaaga tttaatctca
    51901 aaaaattttt cagaagataa tgtgtatttg aaaatattgc cagaaattat aaagtatgct
    51961 caaaaacata atgtttgtat cagtctaggt gcaacattta gatcaggaaa catatttgat
    52021 tctaatgata gagcacagat aacagaaatt aagagtcaaa tagaattagc taagaggata
    52081 tataaaagta atgtcggggt tattattgaa tcaccaggtc attcaagacc aagtgacata
    52141 attaaaatat cgtcaatatt aaaaaaagaa ggtttcccaa ttatgccact aggaccaata
    52201 ccaacagata ttgcaatagg aatggatcat atcgctgcag ctattggtgc tacaattatg
    52261 ggtatagaag gatgtgcaaa tataatatca actgtcacac gagaagaaca tactggaggg
    52321 agaccttcta ttgaatccac agttgaatct ataagaacag caaaaatagc tgctcatatt
    52381 attgatatac atcaaatgaa tgatattaac ttagatatga gtgtatctaa gtctagagct
    52441 aaatctaaca cctgtatatt tgggaaagat acaagatatt gtgacagatg tagagaactg
    52501 tgtcctttgt gcattagata aaaattatat tcaagttaat tcaataaaaa agattggata
    52561 aaaatacatc gtatagctag tttttcacaa cagagtcaaa gatatgtcaa attagagcaa
    52621 tttgaataca taattcctcc agaaatagaa aaaatagaaa aagcaaaaga gttatttata
    52681 aattcaatga aaaaatacca agaggattat gataaattag tagagatact atttgaaaat
    52741 cattataaca aactaataaa aggtggtaaa aacgagaaaa catcaaaaag acaagttgag
    52801 aagaaagcaa tagaagatgc tagatacgta tttccaaatg cgtgtgaaac aaagatggta
    52861 tttactataa atgctagaag tttgtttaat ttctttgaac atagatgtta tgaaaatggg
    52921 agttgtctag aaggaactat gacttgtgga gatatagttc aagttagaaa aaaatttaag
    52981 aacttgtagg aggtgaataa tttggcgagt atagaaggaa gaaatccggt aatagaagca
    53041 ataaaaagtg acagagaaat agataaaata ttaattgcaa attcagctaa agaaggttca
    53101 attaagaaaa taataggaat ggctaaagat aagaatataa ttattcagta tgttgataaa
    53161 cataagctag atgaagtaag tacaagtcat tcacatcaag gtgtaatagc ttatgcaagt
    53221 gagtataagt attatgaatt agatgagcta atagatttag caaagaataa agatgaagac
    53281 ccatttttca ttatattaga tgagataaca gacccacata atttgggttc aataataagg
    53341 acagcagatg cagtaggagc acatggagtt atcattccaa aaagaaggtc tgtacacata
    53401 actcctgtag ttgccaaagc atctgctgga gcagtagaat atatgccagt ttgcaaggta
    53461 accaatatag ttaatacaat aaaaagactc aaagaagaag ggctgtggat tgctgcagct
    53521 gatatggatg gagaaacttt ttataaacaa aatcttactg gtcctcttgg tgtagtaatt
    53581 ggaagtgaag gttttggaat atctagattg gttaaacaaa actgtgactt tatagtaaaa
    53641 atgccaatga taggtaatgt tacatcttta aatgcatctg tagcaggtgg aatactttta
    53701 tatgagatat tcagacaaag actggataaa agtaaatagg catgaaaaaa aatataaatc
    53761 attacttaat aatagatggc tacaatatta taaatgcgtg ggacaatttg aaagaactgg
    53821 ctaaagagga cttagaagat tctcgagaaa agcttattga tgacattata gaattttctg
    53881 agtttatggg ttataagact ataatagttt ttgatgctta taatgttaaa aattctcgag
    53941 aaaaagttga aaaaagaaaa cacataacaa tagtttatac aagagaacac caaacagcag
    54001 atagttatat agagaaattt ataacttctt tatcaaagta tgatgatgta aaagtagcca
    54061 ctaatgacta tgcagaacag caaatgattt taggaaaagg tgctactaga atgtctgcaa
    54121 gagaattaaa gttagagtta gatcgttcca agaataaaat gaaggaaaaa aatatcggtt
    54181 tgaggaaaaa aattcagcga aattggttgg aggaaaggtt agataaagaa acattgtcga
    54241 aacttgagaa cattcgtaga aagcgttgaa attactaggt tctttagact ataatatacc
    54301 tataaatttg ttttatatat gggggagatt tacatgttgg tagcaaaaga aaaaagttat
    54361 gagttagtgg acaattgtca gcaggatgag tataacattg tattaagagc aagtgaaggg
    54421 gataaaatag cactagagta cattattact aaatacagaa attttgtaaa ggcaaaagca
    54481 aagtcatatt ttttaattgg agcagataaa gaagatataa tacaagaagg aatgataggc
    54541 ctttataagg cagttagaga ttttgatgga agtaagacca attcatttaa atgttttgcg
    54601 gagatatgta taacaagaca aataataact gctataaaaa ctgcaacaag acaaaaacat
    54661 atacctttaa attcatatgt ttctttgaat aaaccaatat atgatgaaga gtcagacaga
    54721 acacttttag atattatagc tacaagtata gtaacagatc cagaagagct tataattagt
    54781 aaagaagagt taaaaaatat agaatcaaaa atgaacgaat tgttaagtga cttggaatta
    54841 gaagtactag aattatattt aaatggaaag tcataccagt ttatagcgga caagcttaaa
    54901 agagatgtaa agtcaataga taacgcttta caaagggtta agagaaaatt agaaaaacat
    54961 cttgaaaaca gaaatgatta atagtaaaat acttaccata agcttattgt gagcaaaatt
    55021 aatttatatc gaaagataag ggaggaaatt caaaatggct aaagctaaat acgaaagaac
    55081 aaaacctcat gttaatatag ggacaatagg acacgtagac cacggtaaaa ctacattaac
    55141 agcagcaata acaaaaacat tatatgacag atatcaatta ggagaagcag tagatttcgc
    55201 aaacatagat aaagctccag aagaaagaga aagaggaatc acaatatcaa cagcacacgt
    55261 tgagtatgaa acaccaaata gacactatgc acacgttgac tgcccaggac atgctgacta
    55321 cgttaagaac atgataacag gagcagcaca aatggacgga gcaatattag tttgttcagc
    55381 aacagatgga ccaatgccac aaacaagaga gcatatacta ttatcaagac aagttggagt
    55441 accata
//
LOCUS       DAMJYN010000014        54919 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.014, whole genome shotgun sequence.
ACCESSION   DAMJYN010000014 DAMJYN010000000
VERSION     DAMJYN010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 54919)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54919)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54919
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.014"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            123..1358
                     /locus_tag="PC466_000971"
     CDS             123..1358
                     /locus_tag="PC466_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium/proton antiporter"
                     /protein_id="HDF2768366.1"
                     /translation="MGLIFIMFFGGFGTNWNMAKPVAIPSILMSSLGVIITSGVTGMF
                     CHMVIGTSLLEGLLIGAIAASTDAASVFAVLRSQKLNLRGSLASLLEVESGSNDPIAY
                     MLTLILLTLMNNSGVELIAPMVIKQIAFGLAIGFILAKLSVYILRHSNFEIEGFYTIF
                     ITAIAILSYAFSEYLGGNGYLSVYISGIIIGNSRIPLKKSLVHFFDGISWIMQIMLFF
                     MLGLLSFPSKLPNVFGIAMAISIFMIVIARPLATFIVLAKFKFSNKEKLFISWVGLRG
                     AASVVFAIYAVTQGVAIENDIFHIIFFIALLSVGIQGSLIPTVARKLDLVDDNTPVLK
                     TFNDYDGEISSKLIEVNVDEGNKWANKSIIDSNIPDDILIVMIKRKEQVLIPKGSTII
                     KTGDILVLSGDRIEELIQL"
     gene            1434..2246
                     /locus_tag="PC466_000972"
     CDS             1434..2246
                     /locus_tag="PC466_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF2768367.1"
                     /translation="MFSIGMFSKINKITTKTLRYYEDIGLLKPEYVDEFTKYRYYTTE
                     QLPKLHQIITLKQMGLSLAEIKKAVENPEEVENILMNKEKEMLDVIKSEEYKIIKLRN
                     YLMNLKGEVNMNDVIIKSLPKVKVASMRKVLKGYDELFNLFPNVMAEEMMKTGCTCAV
                     PDYCFNIYHDGEYRETDMDVEMCQAINDLKEDTDILKFKELDAVENAVCILHNGPYST
                     LGKTYADAFKWIEDNKYKVVGNPRESYIDGIWNKESEEDWLTEVQIPVKRIL"
     gene            complement(2586..3767)
                     /locus_tag="PC466_000973"
     CDS             complement(2586..3767)
                     /locus_tag="PC466_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDF2768368.1"
                     /translation="MKRQDSKGRNLRLGESQRKDGRYVYKYTDIFGKPQFVYSWKLVP
                     TDKTPAGKRDDISLREKEKQIKKDLDDGIDTVGGKMTVCQLYEKKNNQRKNIKRNTEL
                     GRQYLVNALENDPLGMRAIDTVKQSDAKEWAIRMNGKGYSYKTIDNYKRSLKASFYMA
                     IQDDCIRKNPFNSKLSDVLEDDTEAKVILTPEQEEKLLAFMETDNVYSKYRDEVILLL
                     ETGLRISELCGLTTHIDMLNRVINIDHQLLRDTEVGYYISKAKTKNGKRELPLTERAY
                     QALKRILKNRGKAQPLVVGGYSNFLFLNREGLPKVAGNYESMVRGLIKKYNKTHKDKL
                     PNITPHSFRHTYCTNMANKGMNPNTLQYIMGHANITMTLGYYAHGTFQSAKAELERLA
                     S"
     gene            complement(3748..3882)
                     /locus_tag="PC466_000974"
     CDS             complement(3748..3882)
                     /locus_tag="PC466_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDF2768369.1"
                     /translation="MYYFLEMSDTEIADIMNYTREAVFKHRHRALETMKEILNEKTRQ
                     "
     gene            complement(3882..4172)
                     /locus_tag="PC466_000975"
     CDS             complement(3882..4172)
                     /locus_tag="PC466_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768370.1"
                     /translation="MKPSDFQKTIQCQFECKLKKVVKGIIWNYRKELRRRKNKEISFS
                     ELPDITVESLATWDDYETNYTIFNVCGIDIKVLDDELAEALKQLPEKNVTMY"
     gene            complement(4438..4668)
                     /locus_tag="PC466_000976"
     CDS             complement(4438..4668)
                     /locus_tag="PC466_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768371.1"
                     /translation="MIGLKRRDMNYIMKVGAKAQGVSVSEFRAMLQDTIDKTMESTDP
                     DVQANFKRYFGNKRPTPEEYIYTITKKTKVKV"
     gene            complement(4692..4883)
                     /locus_tag="PC466_000977"
     CDS             complement(4692..4883)
                     /locus_tag="PC466_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003064779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4177 domain-containing protein"
                     /protein_id="HDF2768372.1"
                     /translation="MKKYEYVEINYNAKGVVFLCTDKHKEIIDSYAKTGYHYAGFVPT
                     EIDAKGCMRKIDLIFEKED"
     gene            complement(4998..5138)
                     /locus_tag="PC466_000978"
     CDS             complement(4998..5138)
                     /locus_tag="PC466_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768373.1"
                     /translation="MEQYWWIIIVMVLIVVGLLKIVIMKKYNQRRNSNNRSKNSEDDK
                     MY"
     gene            complement(5191..6102)
                     /locus_tag="PC466_000979"
     CDS             complement(5191..6102)
                     /locus_tag="PC466_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HDF2768374.1"
                     /translation="MEKGRLLQNENINKAIQVSKITLIINLGLSLLKFAAGYIGKSSA
                     MLSDAVHSASDVLSTIVVMVGIKISEKQPDKEHPYGHERMECVASIILSVALAITGAG
                     IGYSGIKKIFSGQYNTLSVSSGIALTAAVLSIVIKEWMYWYTRSAAKHTNSDALMADA
                     WHHRSDALSSVGSLIGILGARLGYAILDPIASIVICGCILKAALDIFKESINKMVDHS
                     CDNATETKIREVVLQQQGVDGIDELKTRMFGAKMYVDIEILADGNLALYDAHRIAEGV
                     HQTIENNFPQCKHCMVHVNTNELPYSP"
     gene            complement(6114..6812)
                     /locus_tag="PC466_000980"
     CDS             complement(6114..6812)
                     /locus_tag="PC466_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002583502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2768375.1"
                     /translation="MKRILSSTIQVFKQIKSDPMMFAACFTPFVMGALIKFGIPFLDG
                     ITDFSLQTYYPIFDLLLSIMAPVLLCFAFAMITLEEIDDKVSRYFSITPLGKSGYLFT
                     RLGVPSIISAVIAFIVLLLFSLEKLSIGMTICLALLGSVQAIIVSLMIITLSSNKLEG
                     MAVTKLAALTLLGIPAPFFIDSYYQFAVGFLPSFWVAKAMQNEAVLYFSIGLMVALVW
                     YYFLIKRLFRKLAG"
     gene            complement(6809..7492)
                     /locus_tag="PC466_000981"
     CDS             complement(6809..7492)
                     /locus_tag="PC466_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016295773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2768376.1"
                     /translation="MRLGRLICGDIHFQWKYGFYFIYFILTVLYVCGIAALTGHWKTD
                     IASIMIYSDPAAMGLFFMGAIVLLEKSQKVLNAMVVSPVKVSEYILSKTIALIAISTI
                     IAVILGFVSGSNHLLGIAVGTALTSAIFTMLGIIAATKISNLNQFLIVIMPIEIVCFV
                     PPIVGLFVKLPDIFRFFPFTACMNLITGKSILLSFDMVLVIATLIILYIVARHTVKHM
                     WRSLGGVKL"
     gene            complement(7489..8334)
                     /locus_tag="PC466_000982"
     CDS             complement(7489..8334)
                     /locus_tag="PC466_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2768377.1"
                     /translation="MIDVKKLYFSYTDKPFVENVSFHVGRGEIFGFLGPSGAGKSTIQ
                     KILTGLNTSYKGSVKVAGTEIREHTNRFYENIGVDFEFSTCYEKFTARQNLAYFASLY
                     DKQPRSIDELLHMVGLENDGDKKVADFSKGMRSRLNFIKALVHDPDILFLDEPTSGLD
                     PTNNRLMKDIILAEKKRGKTIIITTHNMYDATELCDQVAFIVAGKVSALDSPHNLIMS
                     RGAAKIHYTYYDKGEKTGECLLDRTTEDKLLKSLISENRLLSIHSSEPTLNDIFVDIT
                     GRTLQ"
     gene            complement(8438..9019)
                     /locus_tag="PC466_000983"
     CDS             complement(8438..9019)
                     /locus_tag="PC466_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2768378.1"
                     /translation="MPRFTEQEKEIINSKLLIEGEKLFSLYGLKKVTVDDLAAAVNIS
                     KGSFYAFYPSKEHLYVEINFRLQKELFTSIETTVKKKKYKNHRDLAKDVIMLSLTGVI
                     TSPILSQIDLSLMDYLQRKISSDIFENHMYSDIRILEILEGLGVVFLVPHTVIIKSLY
                     SVLSCLEQFKEDEELNMVQNLLVNGIIQQVVAE"
     gene            complement(9097..9954)
                     /locus_tag="PC466_000984"
     CDS             complement(9097..9954)
                     /locus_tag="PC466_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002585362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF2768379.1"
                     /translation="MYKEVGISSNNVPITLSIWYTERNSPTIVFLPGTMSHPLMYENF
                     LCGLSERGFNIIGIHYLSHGKSPKIKKNYTMEDLLHNVYDATTYGIENFGENIAVMGS
                     SQGGILAAMAAGRDTRLKAVFPHNIMLTTLKETMSLTKYPAWSHRFMGLIQLGFRVGG
                     KLLPNYKVPGDAYLDYDRVFYSEQAKQDCLNDPMLLPYYPLRFVASLFNADLSCLENG
                     AIQCPVILITAKGDPLFRFDYTNKVFDLIHVPKKELLTLELNRHMIFNEDTDTTINAL
                     EATLHKYLG"
     gene            complement(10167..11060)
                     /locus_tag="PC466_000985"
     CDS             complement(10167..11060)
                     /locus_tag="PC466_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HDF2768380.1"
                     /translation="MFKKKEKPVKETKVRTMKVGTHKKSVIALWVVLIASVSFGVYKN
                     FTAIDMHTVHETETIQLRLNDTNGVENFVKNFCKSYYTWDNSKEAIEARTQAISNYLT
                     KELQDLNLDTIRTDIPTSSTVTNVLIWDIKQSGTNDFIATYEVDQQIKEGEQTSNVKA
                     TYTVKVHVDKDGDMVIVQNPTIAPAIEKSDYEPKAQEADASVDADTVNDATAFLETFF
                     KLYPTATEKELAYYVAGNVLEPIGRDYLYSELVNPMFTDDRDNVKVRVAVKFIDNQTK
                     AMQVSQFELVLHKDSNWKIIM"
     gene            complement(11076..12083)
                     /locus_tag="PC466_000986"
     CDS             complement(11076..12083)
                     /locus_tag="PC466_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009243519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HDF2768381.1"
                     /translation="MKLRHIAIVGSLFSILFSLVLFFGVLISAEDDDGGNGYSSNYVG
                     MNLSAEVLKHQPMVEKYAKENGISEYVNVLLVIIQVESGGTAEDVMQSSESLGLPPNS
                     LDTESSIKQGCKYFASLLSSCKNQGISDINVVIQSYNYGGGYVGYVAGNGKKHMFNLA
                     ENFARDKSGGQKVTYTNPIAVAKNGGWRYGYGNMFYVELVNQYLVVNQVSGELAQKVM
                     NEALKYQGWKYVYGGSNPNTSFDCSGLVQWCYNKAGVSLPRTAQNQYDATQHIPLSQA
                     KAGDLVFFHSTYNAGSYVTHVGIYVGNTQMYHAGDPIGYADLNNAYWQQYLICAGRIK
                     Q"
     gene            complement(12080..14215)
                     /locus_tag="PC466_000987"
     CDS             complement(12080..14215)
                     /locus_tag="PC466_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HDF2768382.1"
                     /translation="MKERIKSVFTRKKIFRFLKMALFVVALSLILLSLLGTVAHATGL
                     VDDTINTENLYSKYPLSNYQLDFYADNNWAWLPWNWLDGIGKSVQYGLYCITNFVWTI
                     RLYLSNATGYVVQEAYKLDFINDMADSIGRSIQTLAGVTQNGFSTSGFYVGFLLLIIL
                     VVGIYVAYTGLIKRETSKALHAVINFVVVFVLSASFIAYAPDYIKKVNDFSSDISTAS
                     LDLGTKIMLPDSDSKGKDSVDLIRDSLFSIQVQQPWLLLQFGNSGIEEIGADRVEALV
                     SASPEDEDGKTREEVVKTEIEDNDNNNLTILQVVNRLGMVFFLLFFNLGITIFVFLLT
                     GMMLFSQILFIIFAMFLPISFLLSMIPSYESMAKQAIVRVFNTIMTRAGITLIVTVAF
                     SISSMFYNISTDYPFFMVAFLQIVYFAGIYMKLGDLMSMFSLNAGDSQSMGRRIFRRP
                     YLFMRHRARRMEHRLARAVSAGGVAGAVAGGVVASSKSTRQNGTKNNRGNTSSSMGQK
                     AGSAVGAVLDTKNKVKDKATAVKENIKDMPTQTAYAVHSAKEKAKSSVSDFKRGVVQE
                     KENRQSGRLKKQQLHRQNIADKRMELQKAQESRQAGKKTDGSATSGATRPHERPATTS
                     KVNVEKQQEVKRPAIASTVKNDEPIKKNVVKERPLSSGDTSAKTVNQETTRQNYKTDR
                     VTKTTVQKHTQQNTEKNKRTVFKKGQKKK"
     gene            complement(14215..16647)
                     /locus_tag="PC466_000988"
     CDS             complement(14215..16647)
                     /locus_tag="PC466_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF2768383.1"
                     /translation="MFPIKYIDNNLVWNKDNEVFAYYELIPYNYSFLSAEQKFIVHDS
                     FRQLIAQSREGKIHALQIATESSSRSIQEQSKKLVTGRLKDVAYQKIDEQTEALVSMI
                     GDNQVDYRFFLGFKLMVTDQSMNLKSVKQSAFLTFKEFIHEVNHTLMNDFVSMPNDEI
                     NRYMKMEKLLENKISRRFKVRRLDKNDFGYLIEHIYGRDGVAYEDYEYSLPKKKLKKE
                     TLITHYDLIRPTRCLVEESQRHLRLEHEDSESYVSYFTVNAIVGELDFPSSEIFYFQQ
                     QQFTFPVDTSMNVEIVENRKALSTVRNKKKELKDLDNHAYQSGSETSSNVVDALDSVD
                     ELETDLDQSRESMYKLSYVIRVSAPDLDELKRRCDEVKDFYDDLNVKLVRPAGDMLGL
                     HSEFLPASKRYINDYVQYVKSDFLAGLGFGATQQLGENTGIYIGYSVDTGRNVYLQPS
                     LASQGVKDTVTNALASAFVESLGGGKSFCNNLLVYYSVLFGGQAVILDPKSERGNWKE
                     TLPEIAHEINIVNLTSDRENAGLLDPFVIMQNVKDAESLAIDILTFLTGISSRDGEKF
                     PVLRKAVRAVTQSDQRGLLHVIEELRKEDTPISCNIADHIDSFTDYDFAHLLFSDGTV
                     QNAISLDNQLNIIQVADLVLPDKDTTFELLSVSMLIVISTFALDFIHSDRSVFKIVDL
                     DEAWAFLNVAQGETLSNKLVRAGRAMNAGVYFVTQSSGDVSKESLKNNIGLKFAFRST
                     DINEIKQTLEFFSIDKEDENNQKRLRDLENGQCLLQDLYGRVGVVQIHPVFEELLHAF
                     DTRPPIQRNEVE"
     gene            complement(16634..17023)
                     /locus_tag="PC466_000989"
     CDS             complement(16634..17023)
                     /locus_tag="PC466_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009274602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HDF2768384.1"
                     /translation="MKKIKSYTGIWNVEKVLYAINDFNLPFPVTFTQITWFVITEFII
                     ILFGDLPPLSMIEGAFLKYFGIPVALTWFMSQKTFDGKKPYSFLKSQITFALRPKITY
                     AGKAVKLDKQVLHEAITAVRSVSYVPD"
     gene            complement(17136..17639)
                     /locus_tag="PC466_000990"
     CDS             complement(17136..17639)
                     /locus_tag="PC466_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HDF2768385.1"
                     /translation="MVEDMRVYIANLGKYNEGYLVGDWFSFPIDEEDVAERIGLNERY
                     EEYAVHDTENFPIEIGEYISIEELNEMYEMICELPDYITDSLDEFVSNYGSLEELYDH
                     RDDMILYAGCEDMTDVAYYFIDELQALGDIPPSLQNYIDYEAYGRDLSFEGTFIETRY
                     GMCEIPW"
     gene            complement(17655..18152)
                     /locus_tag="PC466_000991"
     CDS             complement(17655..18152)
                     /locus_tag="PC466_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HDF2768386.1"
                     /translation="MNEMRVCIESRLHTSEEIRSAWFTLPIDEEELEEQIGVPIDSED
                     YHIVEKELPFADEVGEDATIEKLNDLYHTFESLPADLQEDYGELMCYFTSLDELHQHR
                     HDVIHYSWCKNMADVARHLLDNDPAFSAIEERLTRYFDYEAYGQYLDDNGEFIETDHG
                     IYELP"
     gene            complement(18173..18361)
                     /locus_tag="PC466_000992"
     CDS             complement(18173..18361)
                     /locus_tag="PC466_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768387.1"
                     /translation="MKDIFSDMQASIGCTYISDLPHHKRMVWQEMKRLNLADYPQKQL
                     EDFAGYVFGVPYTSIAEA"
     gene            complement(18438..19076)
                     /locus_tag="PC466_000993"
     CDS             complement(18438..19076)
                     /locus_tag="PC466_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloramphenicol acetyltransferase CAT"
                     /protein_id="HDF2768388.1"
                     /translation="MEYKYTKIDLNKWNRGKLFQSYIDNMRIVMSLTVDIDVTKFIEF
                     SKKHDLKFYPAMIWAVSKVVNEHDEFKYSWDNNGNLIKWDYISPSYTEFHKEDENFTK
                     IVTDFSDSIFEFHKRFILDREKYKTERAFVENQSLNFFDVSCLPWVKYNHFDVHVFDE
                     GKFLAPVITWGKYELEQERYIMPLTMNIHHAVADGFHLSRFFNEVQELINSI"
     gene            complement(19396..19617)
                     /locus_tag="PC466_000994"
     CDS             complement(19396..19617)
                     /locus_tag="PC466_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768389.1"
                     /translation="MNFGQNLYTWFLSNAQSLVLMAIVVIGIYLGFKREFSKLIGFLV
                     VALVAVGLVFNAGGVKDVLLELFNKIIGA"
     gene            complement(19618..19752)
                     /locus_tag="PC466_000995"
     CDS             complement(19618..19752)
                     /locus_tag="PC466_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HDF2768390.1"
                     /translation="MWELIKDLLLVSLGMGIGVVLMCIMSVGKEADRHMIELKESEEK
                     "
     gene            complement(19759..20880)
                     /locus_tag="PC466_000996"
     CDS             complement(19759..20880)
                     /locus_tag="PC466_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HDF2768391.1"
                     /translation="MAGISREHLSRIEAGKVALTEDMKHKLLEAVEKFNPDAPMFLLF
                     DYVRIRFPTLDIQHVIKDILKLNIDYMLHEDFGHYKYTEHYYIGDVFVYTSQDKEKGV
                     LLELKGKGCRQFESYLLAQERSWYDFLMDALVDGGVMKRIDLAINDRTGLLDIPELIE
                     KCKNEECISKFRSFKNYGSGELVKHNEANKDGMGHTLYIGSFTSEVYFCVYEKNYEQS
                     SKLGIPIEEVPIKNRFEIRLKNEHAYYAIRELLTHYDAELTAFSIINQYIRFADKEAN
                     KRKSDWKTNARWSWFIGEGRPPVKLTTKPEPYTLQRTLNWLQRQVAPTLKMLKQIDAG
                     NQMDYLKTIEQQAKLTDKHKQIIRQQTASVDELIEKEKE"
     gene            complement(21160..22554)
                     /locus_tag="PC466_000997"
     CDS             complement(21160..22554)
                     /locus_tag="PC466_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008787614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF2768392.1"
                     /translation="MRMILNKGHRIRARDKNLVYHFSIGTLLFVFVAVLLLLNIKQLM
                     RTDWEHFSLLDNGLTLSPYNFITILIATGICALVAFLYYRFCYDSFKKLLHRQKLARM
                     ILENKWYEADTVQDSGFFTDLQSRSREKIVWFPKIYYQMENGLLHIHCEITLGKYQDQ
                     LLRLEDKLESGLYCELTDKTLHDGYIEYTLLYDMIANRISIDEVKAENGCLRLMKNLV
                     WEYDVLPHALIAGGTGGGKTYFLLTLIEALLHTNAVLYILDPKNADLADLGTVMGNVY
                     HTKEDMIDCVNAFYEGMVQRSEEMKQHPDYKTGENYAYLGLPPCFLIFDEYVAFFEML
                     GTKESVSLLSQLKKIVMLGRQAGYFLIVACQRPDAKYFSDGIRDNFNFRVGLGRISEL
                     GYGMLFGSDVKKQFFQKRIKGRGYCDVGTSVISEFYTPLVPKGHDFLQTIGSLAFVRQ
                     DGTATCEAKGDGTD"
     gene            complement(22664..23191)
                     /locus_tag="PC466_000998"
     CDS             complement(22664..23191)
                     /locus_tag="PC466_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcxB family protein"
                     /protein_id="HDF2768393.1"
                     /translation="MTNGGIPLETVELRFQYTQSEYIKAERQYLISSKTIHKYDIALV
                     AVFLLLSVVYMLFSSFSVFSILIFGLIIVVTALGSYLYILMPILKFKQTAKYHEEYTL
                     VFSKENIKFKTQSIDSEVKWDIYSALWESHDFYYLIQAPRLYTLIPKRIFKDLNEKQL
                     FEEIAQSRVKTTKHI"
     gene            complement(23227..23769)
                     /locus_tag="PC466_000999"
     CDS             complement(23227..23769)
                     /locus_tag="PC466_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HDF2768394.1"
                     /translation="MKGFERKNQLFSLCGLNCGLCPMLLGNYCGGCGNGNQSCRIAKC
                     SLEHGQIEYCYECKQYPCEKYQHIDDYDSFITHKRRKADLERAKNIGIEQYNLEQQEK
                     TQILSYLLSNYNDGRRKTFFCVAVNLLELSELQEAMKQIQSNDELTLLPFKAQCLYVV
                     EVFQKIAERRNIKLKLFKKK"
     gene            complement(23794..24252)
                     /locus_tag="PC466_001000"
     CDS             complement(23794..24252)
                     /locus_tag="PC466_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDF2768395.1"
                     /translation="MKLKNPMLVVTDIDKSVEFYKKVFGLYVIMDFGANKTLTGGLAL
                     QTSETYKEFIGTSDISFGGNNFEVYFEEEDFDKFADRLKEYDIEYVHPIIEHSWGQRV
                     VRFYDPDKHIIEVGENMKIVCKRFLNSGMTPEQVAERMDVPMKFINACMR"
     gene            complement(24359..24772)
                     /locus_tag="PC466_001001"
     CDS             complement(24359..24772)
                     /locus_tag="PC466_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3788 domain-containing protein"
                     /protein_id="HDF2768396.1"
                     /translation="MLDKIPNAEEMTALVGQSLYSVWNELCALIDEKYEMECLWNKGG
                     KAWNYEYKYRRGGKTLCALYARENCVGFMIILGKDERLKFDTYRDNYSKEVQRIYDET
                     KTYHDGKWLMFEPTDTTLFDDFVKLLRIKRKPNRK"
     gene            complement(24868..25251)
                     /locus_tag="PC466_001002"
     CDS             complement(24868..25251)
                     /locus_tag="PC466_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014080829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HDF2768397.1"
                     /translation="MRLTNGIVLDNEKTFGVLKFSALRHEVRVENEDGTTSDEIKRRT
                     YDLKCSVQERMIQVSIPADVPVKDFPYNAEVELINPVADTVANANFRGTTVDWYIKAD
                     DIVLKNKGGQAGNPQNNAPQGQQKK"
     gene            complement(25266..25589)
                     /locus_tag="PC466_001003"
     CDS             complement(25266..25589)
                     /locus_tag="PC466_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014080830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HDF2768398.1"
                     /translation="MELKYIVPNVAQTFGNLEFAGENKVDQQRINGRYTLVSRSYNLY
                     SDIQRADDIIVVLPAKAGEKHFKPEQKVKLINPRITAEGYNVKGRGFTNYILMADDML
                     PAESK"
     gene            complement(25814..28474)
                     /locus_tag="PC466_001004"
     CDS             complement(25814..28474)
                     /locus_tag="PC466_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VaFE repeat-containing surface-anchored protein"
                     /protein_id="HDF2768399.1"
                     /translation="MKKILKRLCTGFLAFATVVTALPSSTVHASNTQYWTESKERVSI
                     VEQVMNDGSISSTFNEGHLTVEGEDAYCIDINTAFKNGYKTKADASTRMSADQIADVA
                     LSIEYVKQYTDIHSGISSKHAYLLRQLVVWQRLSVQPDWQWDNVRASYDEIPKAVQDE
                     VFAGAKAFVKENKGRYDCGGYIYSGEGQELGQFWAKLAVGNTKLQKTSTNANITDGNG
                     IYSIAGATYGVYSDKDCTKQLTTLTTDTSGNTEAVEVRATIVYIKELSAPAGFKIDKT
                     VYSLSVEVGKTATLKVSDTPKVTDTLIELFKIDMETQKSNPQGNASLEGAEFTWNFYA
                     GYYNKNNLPAQPTRTWVTKTIAEKDSDGAIHYITRLADKYKVSWDSFYTQDGKNVLPL
                     GTLTVEETKSPSGYLLEGTYMQADGSEEQIKGMYLTQITEDGDLAVLSGSNQYHVSDK
                     VIRGGVKIQKRDLETKDTKAQGGATLKDTAFEIISLNENAVLVEGKLYKKNEVLKTIH
                     TDIEGIASTSADLLPYGKYRLSEQKPPEGYLTDGAKPIDFEITENGKIVDLTDEAHSI
                     YNQIKRGDIEGVKIGAGSHKRLADVPFRITSKTTGESHVVVTDDNGQFSTASDWASHK
                     HNTNAGKTSEDGVWFGTSEPDDSKGALLYDTYIIEELRCESNKGFKLIPPFEIVISRN
                     KVVVDLGTLTDEYEKEITIHTTATSKDGEKTILAGKDVTITDTVKLDGLTKGTKYQLK
                     GWQMLKEENAELIINDKRIENDYIFTADSETMEVKIEFTFDASNLGGKQLVTFEELYD
                     LSNPDEPIKVAEHKDIEDDGQTVTIKEVPETPTPEEPEKPTTPDTPTKTDSPKTGDNT
                     NILAFAIMMFVSAGGLAGTYFFKHRKMKKS"
     gene            29023..29640
                     /locus_tag="PC466_001005"
     CDS             29023..29640
                     /locus_tag="PC466_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 domain-containing protein"
                     /protein_id="HDF2768400.1"
                     /translation="MEIFAIGHSNYPYDKLINMIKKYDINCVVDIRETPYSKYNIQYN
                     KEAFNESLRNSGFIYIYMGKEFGAKRNNKDVYTQEGYADFEKVAKEDIFLNGIERLKK
                     GCQMGYRIVLLGAMQEPIRCHRSILVGKVLNKEGFDVKYIMHEGNLAYQEDIEESLLD
                     KYFSDREQLSIDNLLGSALTREEMIQEGYKLANKEIGYRTEKLGK"
     gene            complement(29797..30249)
                     /locus_tag="PC466_001006"
     CDS             complement(29797..30249)
                     /locus_tag="PC466_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="staygreen family protein"
                     /protein_id="HDF2768401.1"
                     /translation="MVNLNANNLNVNMVYPISSTAPIRFRRYTVSYLENMENIYLTIA
                     TYFDTLGLGTMNIDKVYGQWAWFTDNIYDLNLFVFVGNYPYQIAKNRYDTFVDILPVA
                     ITSIVNGDRVFLISNPCLLNSKITVRFISSHPTLNRTVDYGNIRDFIF"
     gene            30697..32055
                     /locus_tag="PC466_001007"
     CDS             30697..32055
                     /locus_tag="PC466_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF2768402.1"
                     /translation="MFIRKNVIKLAIPIMIEQTFVMLLGVFNTIMAGHIGEEAVSAVG
                     MVDSINNIFISVFAALSVGATVVVAQQIGKKDSEKVNETIKQALVSGVILSFTITILM
                     WVFRTGVINLFYGSAEELVKSNAKLYIEFTLFTYPFIATQQIANGILRGCGDVKKPMY
                     VTMFMNIVNVTLGYILIYGIDLNPLGINLQTPSYGITGAAISIAIARIIGCIVIIRAL
                     FKGNEFISMGKIFPFKIDVETQKSIFNIGIPAGVEQLLFNAGKLIVQVFIVTMGTSAI
                     ASNAIGMSIASIINVIGNALALSATTLVGQYIGRGDIKGAKSTLLYLTKFATICLFIV
                     GAIFIPIAPWISSMYTQNASVIDISTQLIRSDCLAMVIWPISFVLSAGLKGAGDTRYT
                     MMTAVIGMWIFRIFTGYVLGVVLEFGVLGIWIGMYTDWLVRGTLYCLRLRGTKWLKHK
                     VA"
     gene            32328..32708
                     /locus_tag="PC466_001008"
     CDS             32328..32708
                     /locus_tag="PC466_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDF2768403.1"
                     /translation="MINKIGKITLYVNNQEDAKLFWTEKLNFVVTYEKEMGPNMKWVE
                     VAPSKNEFTTFVLYDKNLMMKQNKEINVSHPSIILSTRDINGTYEQMANNEVEVGELM
                     EMPYGRMFSFKDQDGNDYLVREDK"
     gene            32833..33033
                     /locus_tag="PC466_001009"
     CDS             32833..33033
                     /locus_tag="PC466_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768404.1"
                     /translation="MFKKMAVLKDIATKIGRKKAYELLEMVEGNDAFVAEVKIKKNGI
                     ESKKEEIMLKDNQKIILEYIEG"
     gene            33229..33957
                     /locus_tag="PC466_001010"
     CDS             33229..33957
                     /locus_tag="PC466_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF2768405.1"
                     /translation="MLEIKNLSFNVESNNEELGIINDVSLSFERGKLIVITGPNGGGK
                     STIAKLIMGIEKATSGQIILDGEDITNLSITERAKKGIGYAFQQPPRIKGMTVENLLT
                     LAHGKPLSTDVCCQYLTDVGLCSKDYLNREVDNSLSGGEMKRIEIATLFARDLKVSIF
                     DEPEAGIDLWSFGKLNESFKKIHEESNQTIIIISHQERILELADEIIVLQDGSVKSHG
                     TKEAILPEIMCQVNSSCELMKDMN"
     gene            33979..34896
                     /locus_tag="PC466_001011"
     CDS             33979..34896
                     /locus_tag="PC466_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SufD family Fe-S cluster assembly protein"
                     /protein_id="HDF2768406.1"
                     /translation="MNKIDLNLLEKVAELRGTPLGAYNIRKNGQGVERHSTENVTIIP
                     KTDKPGIDIIVKPNTKGENVHIPVIVTEAGVQDMVYNDFEIGENADVVIIAGCGIHNC
                     GCDDSEHNGIHRFFLRKGARLKYVEKHYGEGDGEGKRILNPVTIVNMDEDSYCEMETI
                     QIKGVDSTKREMDANLGKGAKIVVFEKLLTHGNQVAESNMKVILEGENSSAQVVSRTV
                     GQDNSKQKFNPCVIGDSLCSAHVQCDSIIMGNSQISAIPEIAANHPDALLVHEAAIGK
                     IAGDQILKMMTLGLTEEEAEQQILNCFLK"
     gene            35038..36222
                     /locus_tag="PC466_001012"
     CDS             35038..36222
                     /locus_tag="PC466_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HDF2768407.1"
                     /translation="MKNLLIRNGTIISPTDGIKFEKRDILVLHGKIYAIGLNLKEKIR
                     KEKLLTNKEFEIINADNMYISPGFIDVHTHCYKRKLPTGMDSDSIGIEKGSTVIFDAG
                     TAGPSNYYDFKKKYMDECKTEVYSFLNVTNEGLNILNESTSLDVINFDKVESIVEKNI
                     EKIKGIKVKASKFQSNESGIDIIKKSKQVAKKLNLPLVVYIGEYPSYIDEVMNILGKG
                     DVVTPVYGNSTNGILKESGTLRKSVINAKNRGVLFDVCHGVDQFDFKVFKKAIKQGLE
                     PDLISTDMHIKNMKDVNYSLLNVINKIMELGISLEKCIEKVTEYPTKIFDLHGNKGRI
                     KIGGEGDFTIFTMEECNDIIKDYNNNELVLNKKLRLQYTVKSWMKSSEVYRHGYENTI
                     IN"
     gene            36329..36517
                     /locus_tag="PC466_001013"
     CDS             36329..36517
                     /locus_tag="PC466_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HDF2768408.1"
                     /translation="MKAFVDKDVCVACGACIGTCPDVFSMSDEGHSVAIEGEIPADLQ
                     DLCKEAEEGCPVSAITVK"
     gene            36667..37317
                     /locus_tag="PC466_001014"
     CDS             36667..37317
                     /locus_tag="PC466_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HDF2768409.1"
                     /translation="MKKNYEIVLFDLDGTLTDPKEGITKSIQYSLNSFGIKEDLENLD
                     QFIGPPLHDTFKEYYKFEDKKAKEAVEKYREYFADKGIFENKIYENMKEILEMLYKNG
                     KILLVATSKPTVFAETILRYFDIDRYFKYIAGSNLDGTRVNKNEVIQYVLDLCNVKDK
                     DKVIMVGDRKYDIIGAKKIGIDSIGVLYGYGSFEELSESEPTYIVENVESIKDILL"
     gene            37420..38358
                     /locus_tag="PC466_001015"
     CDS             37420..38358
                     /locus_tag="PC466_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDF2768410.1"
                     /translation="MKSILIMGGSDFIGSALAKRLIKCGYQIDILTNGKKEIDYNGFK
                     EHLICDRKVRKDMENIITGRKYDYIYDMTAYTKEDVSNLIDFISMDNLKKYIVLSAGA
                     VYKDSGRNIKEENEKGENENWGKYGLNKKEAEDFIINSPIPYIIIRPTYIYGENNNLY
                     REYYFFEKIEKNEKIPVPKGKQVSNQFIYIGDLVKVLESIMKNPHVREAYNVTNPQLI
                     SWDDLIYTCGEIIGKEPIIKYVDMEKVEFRERTYFPFRNIDFNLDINKLIEHGLYIPN
                     VLLKEGLTATYKWFSANKPKMHDRKMNKVESVMQIV"
     gene            38384..39235
                     /locus_tag="PC466_001016"
     CDS             38384..39235
                     /locus_tag="PC466_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HDF2768411.1"
                     /translation="MNSKIKYFLKFFILIFILIFIYSVAIEPSLLIVKKYNISENGAL
                     IKNDTIESKSESVKVVQISDTQIGSFYSTKNLKKVANKINTLNPDIIVFTGDLIDYSN
                     KNPSVDEITTILSSMNARLGKFSVFGNHDYMYKLPRYYRQIMKNSNFNLLVNENKKIK
                     LKDDKYINILGVDEILNGNPNIKYLESQIDNKNFNLLLAHEPDLVDMLSKDTMNLVLS
                     GHSHGGQIRLPIKGALVTPPYGRKYTKGFYDINGNHLYVSSGLGSTKLPFRFFNIPEI
                     IEFNIII"
     gene            complement(39520..40254)
                     /locus_tag="PC466_001017"
     CDS             complement(39520..40254)
                     /locus_tag="PC466_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiocytidine biosynthesis protein TtcA"
                     /protein_id="HDF2768412.1"
                     /translation="MSIQKLLSKARKAIQDFDMIQENDKIAVGLSGGKDSLTLLHILK
                     SYQRFSPQNFELIAITLNTGGVDNSPLDKLCKEINVPFYEFQTDIKEIVFDIRQEKNP
                     CALCANLRRGALNDNAKKLGCNKVALGHHKDDAIETFLMSMFYEGRVNCFSPKTYLDR
                     QDLTVIRPMIYIEEYMTKKISKDSNYPIITNPCPANGHTRREYIKNLIANLNKEMPDF
                     KRNVFGALNNSEKLFIWDKEKIKNFK"
     gene            40380..41096
                     /locus_tag="PC466_001018"
     CDS             40380..41096
                     /locus_tag="PC466_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HDF2768413.1"
                     /translation="MKKFKLIGAIILVVFISVFISKDRLLKKDKDPIVAAQHDSEQDV
                     EANSQNKNHSNSISNILLVNKTNGISKNYTPENITKVNIPFVEEATEEEKQMAGEPAK
                     AVEDLVKQANSEGIQFLGSSAYRSYDTQLDTYTRRVKSQGREKADAYVAKPGYSEHQT
                     GLCIDLTNPERWFVGSTKEAKWLAENAHKFGFIIRYPEGKEDITGTAYEPWHIRYVGK
                     DAAEEIYSKGLTLEEYLQNK"
     gene            41230..41922
                     /locus_tag="PC466_001019"
     CDS             41230..41922
                     /locus_tag="PC466_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011948339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2768414.1"
                     /translation="MNNTVLVVDDEKEIRDLIEIYLLNSGYNVIKAEDGKEALDILKK
                     ENIHLMILDIMMPKMDGIEVCRKVRESLNIPILMLSAKSEDMDKIQGIMTGADDYLTK
                     PFNPLELTVRVKSLIRRAYYFSGANNEDKDVIKVGVVIIDKEKHSVTVAGNEIILTSR
                     EFDILYLLANNKGRVYSTEEIFEKVWKEKYYQSNNTVMVHMSRIRDKIEKYTDGEKII
                     HTVWGVGYKIEK"
     gene            41912..43093
                     /locus_tag="PC466_001020"
     CDS             41912..43093
                     /locus_tag="PC466_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HDF2768415.1"
                     /translation="MKNKSLLNHMFRPILDLIISCALTSMLILTSMYIIKLLYFNSEI
                     SVINQLVYQLRDFRSLIGESLFYPFLFTITSLAIYSMISYKRNKQIVDFIRKTNRKNQ
                     KLEIIKSAVNLMDEGNLEKSIDIEYDLDILKDKEKDDIDELAHKINNIVHQLRNITIE
                     ERQAQQTKTDLITNVSHDLRTPLTSIMGYLGVIEEGKYKDEVQMMYYVDIAYEKSKNL
                     NVLINDLFELTKMQNNTIKLNKIEINLVELLSQVVSQFEIYFKQEFMVSRINFNEEKL
                     IVKADPNKLVRAFENLITNAVKYGKDGHYVDIVTEKMEDMAVVKVINYGEPIPVLDLP
                     NIFDRFYRVEKSRNRNVGGSGLGLAITKNIVNLHDGEITVSSDKYQTVFEVQLPIIQS
                     A"
     gene            43375..43830
                     /locus_tag="PC466_001021"
     CDS             43375..43830
                     /locus_tag="PC466_001021"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HDF2768416.1"
                     /translation="MEKVESFKLDHTKVKAPFVRKCSVLDGVKGDKVTKFDLRFLQPN
                     VESFGTAAMHGLEHLLATYLRDTLDGVIDLSPMGCRTGFYLILWGDVDAKTVKIGLEE
                     ALKKVLESDKMPAATAIECGNYRDLSLFGAKEYAKDVLDKGFSLNIYGE"
     gene            43820..44545
                     /locus_tag="PC466_001022"
     CDS             43820..44545
                     /locus_tag="PC466_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Vitamin B12 dependent methionine synthase,
                     activation domain protein"
                     /protein_id="HDF2768417.1"
                     /translation="MENNLIGREDISINQSEVLRYLQYRGQEIDKDLKYTIDECVAIT
                     KNKINPRYLSRIYPIRINKDNVVELEGTNLTLESKDVYELLKECNECVIMAATIGIDI
                     EKEIRRHSYSNLTKGLIIDSCGTTAIEEVCDIVQNNLEKVFLNQDKFITMRYSPGYGD
                     LPIEKNIDILNVLNAQKQIGLTITSNGIMIPRKSVVAIIGISNTRINKSKKEKSCENC
                     KNYRNCTYRKGANSCGNKTISEK"
     gene            44517..46898
                     /locus_tag="PC466_001023"
     CDS             44517..46898
                     /locus_tag="PC466_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homocysteine S-methyltransferase family protein"
                     /protein_id="HDF2768418.1"
                     /translation="MEIRQYLKNNILIFDGAMGTMLQQKGLKLGENPEVFGLQNPDKL
                     IEIHTAYLEAGSNVILTNTFGCNELKLDSKYTVEEVIDNAVLVARKAIENVDNTKPRY
                     VALDIGPIGEMLEPMGTLSFDNAYEIFKRQVLQGVKSGVDVIVIETMMDLYEAKVAVL
                     AAKENSDLPIFCTMTFDEGGRSFTGCMPECMVATIEGLGVDAIGVNCSLGPKQLLPIV
                     EKIASRATVPVMVQANAGLPNIVDGEAIYDVDAKEFFEGVKKFVEVGATIIGGCCGTN
                     PSFIKEISENINSVTKGCIEKIDKCVVCSPSKFVEVQSPTVVGERLNPTGRKSLQEAL
                     KNENVDYAINLGLEQVNAGAQILGVNVGLPEIDEKKLMPKLIREIQAVVDTPLQVDSS
                     NVEALEQGLRYYNGRTIVNSVNGKEESLESILPIVKKYGSCVVGLTLDEKGIPKKAEE
                     RFEIAKRIVNRAVSCGIKPKDIFIDCLSLTVSAQQEEAIETIKAITMVKTLGVKTILG
                     VSNISFGLPNRKALNASFLTLALGAGLDLAIINPNEYSMMEAINSFKILNNTDKGCIN
                     YINQYSNINNSKKSDSSTKIDKDLPLDILVERGLKDEAKNVTLNLLKEKDENYILDEI
                     LIPALDKVGKRYDSGDIFLPQLIQSAETVKVSLNTIKETLLSKSSNNVSKGKIIVATV
                     KGDIHDIGKNIVKIMLENYGYEVIDLGKDVPIEEVVEVAKKRNIKLVGLSALMTTTVQ
                     SMKDTIQALRDNEINAKVFVGGAVLTEEYAEEMGADYYSKDAKSAVEIAKLNF"
     gene            complement(47103..48332)
                     /locus_tag="PC466_001024"
     CDS             complement(47103..48332)
                     /locus_tag="PC466_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HDF2768419.1"
                     /translation="MNLNRNLEKYAELAIKVGVNIQPGQILLIKSPIECADFARNALK
                     EAYKCGAKNVYIEWSDEESTLIKYLYAPDEAFHEFPKWTAEQYVDIAKEGGAFLSVYA
                     QNPDLLKDVDPERVANFQKASGKALKEWRSYTLTDKCKWSIVSVPTKDWAKKVFPNLS
                     EDKAIEKLWDAIFKCSRVDGQDPIKAWEEHNENLKSKMDFLNKNNFKTLKYKSSKTDL
                     TLDLPKGHVWLSGASKDPNGISFNPNIPTEEIFGMPHKFKVNGTVYSTKPLVYGGNII
                     DNFFLTFKDGKIIDFSAEKGLDTLEKLIETDEGSHYLGEVALVPYNSPISNTDIIFYN
                     TLYDENASCHFAIGSAYKTCLEGGNNLKDEELDEHGVNDSLTHVDFMIGSADMDIIGE
                     TYDGKQIQIFKNGNWAF"
     gene            48932..49846
                     /locus_tag="PC466_001025"
     CDS             48932..49846
                     /locus_tag="PC466_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768420.1"
                     /translation="MELYEAIFYRKSVRNFSSKKIKKPLMEEIKRSCKNLEYLNEDLN
                     IKAHVVDRGHIIHFLMGKECKVKAPHYIVVTSDKGEDYLQNIGFATEGVVLRLTTLGI
                     ATCWLEGNLKREDILEFVDIGNKNFEEDEEDDLDYLAGVKTEEDDENKIENPYIIIAF
                     GYPAKNEELFRTRYARPDRKPVKDMINKINRNRKWKDILELTRRAPSVKNSQPWYFHK
                     DERGLHLFEKRPKKHCEDMNKVSLGVALRHFDIACIKNKIDVSYEKLPIRNKIGKSYF
                     ITVVEHVKPEEETQEENVTLEKEESQDE"
     gene            49870..50505
                     /locus_tag="PC466_001026"
     CDS             49870..50505
                     /locus_tag="PC466_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1847 domain-containing protein"
                     /protein_id="HDF2768421.1"
                     /translation="MYKCGKCNLRGCSNGNMDKLMKICPTREIELQQKAKQLYEEEEN
                     RKIAYNAGLVEAEGYCQYTRLKEIIEFAKKCGYKKIGIAFCIGLKREMQTAQKIFEHH
                     GFEVFSVICKNGAMPKSTIGLEASQTISKCSDEVMCNPIGQALFLNEAKVDLNVILGL
                     CVGHDTLAMKYMEAPITTLVVKDRVTGHNPVAAIYNAESYFEKKLFDKDEE"
     gene            50881..51597
                     /gene="pyrF"
                     /locus_tag="PC466_001027"
     CDS             50881..51597
                     /gene="pyrF"
                     /locus_tag="PC466_001027"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HDF2768422.1"
                     /translation="MINGKEKLIVAIDTDEFDKAKELIDRLEDSVDIFKVGLEQYVAT
                     KGKTIDYLKEKGKKIFLDLKFHDIPNTMKSAVRAAVRDNVWLMTIHVSDMEGMRQCAL
                     IAREEAERLNIEKPLVVGVTVLTSLSNQDLQDIGCNMTTEELAIKRAKLAKESGIDGV
                     VCSAQEVDKIVEACGADFITVCPGIRPKSAEVGDQKRVVTPSDAIKKGAHYLVVGRPI
                     TKAENPRESAINIVREIENA"
     gene            51623..52666
                     /gene="carA"
                     /locus_tag="PC466_001028"
     CDS             51623..52666
                     /gene="carA"
                     /locus_tag="PC466_001028"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HDF2768423.1"
                     /translation="MKGKLILEDGTVFEGKAFGYLKEAIGEVVFNTSMAGYGEILTDA
                     TYYGQIVTMTYPLIGNYGINLEDVESNKVQVKGLIVREKSDNPNNFRCEMDIDTYLKQ
                     NKVIGLEGIDTRALTKIIRNNGTKRGIITLENVSLQDVQSKLEEHCNKDSVKNVTRKE
                     IENIKGTGAKVVVIDFGVKNSVLESLKACNCDITIAPAMTTVEEILNINPDLILLSNG
                     PGNPEDINDIVENIKKLIGKKPLTGIGLGHQILALALGGKTSKLVFGHRGGNHPVKCL
                     ETGKVFITSQNHGYNVSEMPENTEVTHINLNDNTIEGMRHKELPIYSVQYIPEYTTKE
                     DLDCIFNKFLALI"
     gene            52719..>54919
                     /gene="carB"
                     /locus_tag="PC466_001029"
     CDS             52719..>54919
                     /gene="carB"
                     /locus_tag="PC466_001029"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) large subunit"
                     /protein_id="HDF2768424.1"
                     /translation="MPKLDSIKKTLVLGSGPIIIGQAAEFDYSGTQACQSLKEEGIEV
                     VLINSNPATIMTDKEVADKIYIEPLTIEFIEKIIEKERPDSLLAGMGGQTGLNLAVEL
                     YEKGILDKYGVKIIGTSVESIKKGEDRDIFREVMKEINQPVIVSDIVTDLQAGLDYAL
                     TIGYPVVVRPAYTLGGTGGGIADNEEELREILSHGLQLSPVGQVLIEKSIKGWKEIEY
                     EVIRDSKGNCIVVCNMENIDPVGVHTGDSIVVAPTQTLSNKECAMLKKASLDILNAVE
                     VQGGCNVQFALNPHSFEYAVIEINPRVSRSSALASKATGYPIAKVSSKIALGYTLDEI
                     ENAVTKKTYACFEPTIDYVVAKIPKWPFDKFKKANRKLGTKMMATGEIMSIGSNFEAA
                     ILKGIRSLETGKYSLVHTPSEERSIEELKKRVVVPDDERLFDLAEMIRRGYKVEMIEQ
                     ITGIDKWFINKFKWIVEQEEKLKVMKIEDLTKDYLLELKKKGFSDKGISDLMKISPEK
                     LYELRSLYNIKPAYKMVDTCAGEIDAISPYYYSTYEQYDEVVVSDKKKVIVLGSGPIR
                     IGQGIEFDYCSVHCVKSLRKMDIETIIINNNPETVSTDFDTSDKLYFEPLTEEEVLSI
                     IEKEKPEGVILQFGGQTAIKLAKFLHEKNIPILGTDFDDIDAAEDREKFDDLLERLDI
                     NRPKGKGVWSLNEGIEVANELGYPVLVRPSYVLGGQGMEITYNEEKLSQYL"
BASE COUNT        18775 a         8765 c         9817 g        17562 t
ORIGIN      
        1 ggggatagcc tgtggagaat tagtaagaca tattttagta tgcaaaattc tatgaagcag
       61 gaactctgtg actttagtca tgggaggttc agaactatga attaacaaaa caattatgtt
      121 ctattggact aatatttata atgttttttg gagggtttgg aacaaactgg aatatggcta
      181 aacctgttgc tataccttct atattaatgt cttcactggg tgtaataatt acgtctgggg
      241 ttacaggtat gttttgccac atggtaatag gaactagttt acttgaaggt ttattaattg
      301 gggcaattgc agcttcaaca gatgctgcat ctgtgtttgc tgtgttgcgt tcacaaaaac
      361 taaacttaag gggttcactt gcatcattat tagaagttga aagtggaagt aatgacccaa
      421 tagcgtatat gttgacacta attcttttga cattgatgaa taattctggg gtagaactta
      481 ttgcaccaat ggtaataaaa caaatagctt ttgggttagc tataggattt atactagcaa
      541 aattatctgt ttatatttta aggcattcaa acttcgagat agaaggattt tatactatat
      601 ttataacagc tattgcaata ctttcttatg catttagcga gtatcttgga ggaaatggat
      661 atttaagtgt ttacatttca ggtattatta taggaaatag taggatacct cttaaaaaaa
      721 gtttggttca tttctttgat ggaatttcat ggattatgca aataatgtta ttctttatgt
      781 taggattgtt atctttccct tctaagttac caaatgtatt tggtatagca atggccatat
      841 ctatattcat gatagttatt gcaagaccat tagcaacatt tatagttcta gcaaaattta
      901 aattctcaaa taaagaaaaa ttattcatat cgtgggtagg tcttagaggt gcggcttcag
      961 tagtttttgc aatttatgct gttactcaag gagtagccat agagaatgac atattccata
     1021 taatattttt tatagcgttg ctttcagtag gaatacaagg ttcattgata ccaactgtag
     1081 ccagaaagtt ggatttagtt gatgataata cacctgtatt aaaaacattt aatgattatg
     1141 atggggaaat tagctctaaa cttatcgaag taaatgttga tgagggtaat aaatgggcta
     1201 ataagagtat aatagattct aatataccag acgatatatt aatagttatg ataaaaagaa
     1261 aggaacaggt tttaatacct aaaggttcaa ccattataaa aacaggggat attttggtat
     1321 tgagtggaga tagaattgaa gaattaatac aattataatt tattttgtat tgactttaac
     1381 ctaaggggaa agtttaaact taaattaatc aaatctaatg cgcaggtgat gagatgtttt
     1441 ctataggaat gttttctaaa ataaataaaa taactacaaa gacattaagg tattatgaag
     1501 atatagggtt gttaaaacca gaatatgtag atgaatttac aaaatatagg tattatacaa
     1561 cagagcaatt acctaaatta catcagataa taactttaaa acaaatgggt ttatcattag
     1621 ctgagataaa aaaagctgta gaaaatcctg aagaagttga aaatatttta atgaataaag
     1681 aaaaagaaat gttggatgta attaaaagtg aagaatataa aataattaaa ctacgtaatt
     1741 accttatgaa tttgaaagga gaagtcaata tgaatgatgt aattattaag tctttaccaa
     1801 aagttaaagt tgcttctatg agaaaagtgt taaagggata tgatgaactt tttaatctat
     1861 ttccaaatgt aatggctgaa gaaatgatga aaacagggtg tacatgtgca gttcctgatt
     1921 attgttttaa tatatatcat gatggtgaat atagagagac tgatatggat gttgaaatgt
     1981 gtcaagctat aaatgattta aaggaagata cggatatatt aaaatttaaa gaattagatg
     2041 cagttgaaaa tgcagtttgt atattacaca atggtccata ttcaacatta ggaaaaactt
     2101 atgcagatgc atttaaatgg atagaggaca ataaatataa agtggttgga aatcctagag
     2161 aatcttatat agatggtata tggaataaag agagtgaaga agactggttg acagaagttc
     2221 agataccagt gaaacgcata ttataatatg tctacaaagt ataaataaga ataaaaaagg
     2281 tagtgtctca aagtaaactt tttagtttat gagacactct ttttcatatg aaatcaagtg
     2341 tatttttata attccgatta tgaaaaaagg cttatctcta tttttggaca gcctcttatt
     2401 tttttattat aaaaacttac taaatttctg attatctttt cataagttgg tagatgccga
     2461 tatatcccgc attttcgggc tgtatgggca ttttcttttt ggaagatacc ttgcataagc
     2521 tggcatttac cagcatgaaa atgcaaccaa aagtagtaaa taagtagtaa gatacatttt
     2581 cgatattaag aagccagcct ttctaactct gcctttgcag actggaaagt accgtgagca
     2641 taatacccta atgtcatggt tatgtttgcg tgtcccatga tgtattgcag ggtgtttggg
     2701 ttcattccct tatttgccat gttcgtacag taagtatgtc tgaatgaatg gggcgtgatg
     2761 tttggtaact tgtccttatg ggtcttgttg tacttcttaa tcaacccacg caccatactt
     2821 tcataatttc ctgctacctt tggcaatccc tcacggttca agaataagaa attgctataa
     2881 ccaccaacaa caagcggttg tgcttttcct cggttcttta aaattcgctt gagtgcttga
     2941 tatgctcttt ctgttaatgg aagctctcgc ttaccgtttt ttgtcttagc tttggaaata
     3001 tagtagccca cctctgtatc acgcaatagc tggtggtcta tgttaatcac acggttaagc
     3061 atatcaatgt gtgttgtcag tccgcataat tcagagatac gaagtcccgt ttccagcaga
     3121 agaataactt catcacgata cttgctgtaa acattatctg tttccataaa ggcaaggagt
     3181 ttttcttcct gctctggtgt caggataacc tttgcttccg tatcatcttc cagaacatca
     3241 ctcaacttgg aattaaaagg attttttctg atacagtcgt cttgtatcgc catatagaat
     3301 gaagccttta gggaacgctt atagttatct atcgtcttgt aagaataacc tttgccattc
     3361 attctgatag cccattcttt agcgtcggac tgcttgaccg tatcaatcgc cctcataccc
     3421 aatgggtcat tttccagtgc gttcacaaga tactgtcgtc ctaattccgt gtttctcttg
     3481 atgttctttc tttgattgtt ctttttttcg taaagctggc agactgtcat tttaccgccc
     3541 accgtgtcga taccgtcgtc aaggtctttt tttatctgct tttctttttc cctcaacgat
     3601 atatcatcac gttttccagc aggtgtcttg tctgtgggta caagcttcca agaatataca
     3661 aactgtggct tcccgaatat atcggtatat ttataaacgt atcttccgtc ttttctctgg
     3721 ctctctccaa gacgcaaatt gcgtccttta ctgtcttgtc ttttcattta gtatctcttt
     3781 catagtttct agtgcacggt gtctgtgttt gaacacagcc tctctggtat aattcataat
     3841 atctgcaatc tctgtatcac tcatttccaa gaagtaatac atcaatacat tgttacgttt
     3901 ttttcgggta gctgtttgag agcttctgca agttcatcat caaggacttt aatatctatg
     3961 ccacacacat taaaaattgt gtagtttgtt tcgtagtcgt cccatgttgc cagactttct
     4021 accgtaatgt ctggtaattc gctaaaagat atttccttgt tttttcttcg tcttaattct
     4081 ttgcggtagt tccagataat acctttgaca acttttttca gcttacattc aaactgacac
     4141 tgaattgttt tttggaagtc agacggtttc ataatctcac ctcctttcca gctatgaatt
     4201 gaaaagtgtt tatccctctt tccgcaccat atctgtacag caaggtgtga tttgcttcca
     4261 aaaaaatgaa aataattaaa aaacttttcg ggtattaaaa aagcccgcac aaaatataaa
     4321 ttttgtacga gctactggta tagcgtattt aattgtaaat agtatgctgt taaattgggc
     4381 ttgaatatac tgaattgtat ttaaagcgtt tcatacggca agcccccttt acaacattta
     4441 aaccttaacc tttgtctttt tggtaatcgt ataaatatat tcctctggtg ttggccgctt
     4501 atttccaaag tatcgtttaa aatttgcctg cacgtctggg tctgtacttt ccatagtttt
     4561 gtctatggta tcttgtagca tagccctaaa ttcagataca gaaacacctt gagctttagc
     4621 accaactttc ataatataat tcatatctcg tcttttaagt cctatcatta gaaccaactc
     4681 cctaaaataa gttaatcttc tttttcaaaa attaaatcta tctttcgcat acagcctttt
     4741 gcgtcaattt ctgtgggtac aaaccctgcg tagtgatacc ccgtttttgc ataactgtca
     4801 ataatttctt tgtgtttatc agtacaaagg aatacaactc ctttcgcatt ataattaatt
     4861 tctacatact catatttttt cattcttcaa aactcctttc aaatacaaat ttatctttgg
     4921 atttattgac ttttacaaac tgggatttat cgttcaaatt tcataggtat atatctcata
     4981 ccatcggata attgctctta atacatcttg tcatcctcgc tattttttga acgattgtta
     5041 gaatttctcc tttggttata cttcttcata attacaattt taagtaagcc aacgacaatc
     5101 aaaaccataa caatgataat ccaccagtat tgttccataa cctacttccc ctcctttccc
     5161 tttcaatagt cttaaatcat cttccctgtc ctatggagaa tagggaagtt cattcgtatt
     5221 aacatgtacc atacaatgtt tacattgtgg aaagttgttt tcaatcgttt gatggactcc
     5281 ctcagcaatt ctatgagcgt cataaagagc taaattacca tcagctaata tttcaatatc
     5341 tacatacatt ttcgctccaa acatgcgggt ttttaattca tcaataccat caaccccttg
     5401 ctgctgaagc acaacttccc taatcttcgt ttcagtagca ttgtcacaac tatggtctac
     5461 cattttgtta atgctttctt tgaaaatgtc caaagcagct tttaagatac aaccgcaaat
     5521 cacaatgctt gcaatagggt cgagaatagc atagcctaaa cgtgctccta aaatgccaat
     5581 taaggaacca accgacgaga gtgcatcaga gcggtgatgc catgcgtcag ccataagtgc
     5641 gtcagaattt gtatgctttg cagcacttct tgtataccag tacatccact cttttataac
     5701 aatggataag actgccgccg taagtgcgat tccactagag acagaaagcg tattgtactg
     5761 tcctgaaaag attttcttga tacctgaata tcctattcca gcacccgtta tagccaatgc
     5821 aacagagaga ataatggaag ccacacattc catacgttca tgcccataag gatgttcttt
     5881 atcaggctgt ttttctgata ttttaattcc aaccatcaca acgattgtgc ttaatacatc
     5941 agaagccgag tgtacagcgt ccgacagcat ggcacttgac tttcctatat atccggcagc
     6001 aaatttaagt agcgataaac ccaggttgat gattagtgtg attttggaaa cctgaatagc
     6061 cttatttata ttttcgtttt gcagaagtct acctttttcc ataatatgcc ttcttatcct
     6121 gccagcttcc taaacagacg ttttataagg aagtagtacc agaccaaagc taccatcaat
     6181 cctatggaga aataaagaac cgcttcattc tgcatggctt tcgctaccca aaatgatgga
     6241 aggaagccaa ccgcgaactg gtagtaacta tcaataaaaa agggagctgg tattccgagt
     6301 aatgtaagtg cagctagttt tgtaactgcc ataccctcta atttattgct tgataatgtt
     6361 ataatcataa gcgaaacaat aattgcctgt actgagccga gaagcgccaa acatattgtc
     6421 attccaatgg acaacttttc taatgaaaaa agcaacagta caataaaagc gatgaccgcc
     6481 gaaataattg agggtactcc caaccttgta aagagatacc ccgacttacc aagaggggta
     6541 atcgaaaagt accgtgacac tttatcgtcg atttcctcta atgtaatcat tgcaaatgca
     6601 aagcagagca atacaggagc catgatagaa agtaataaat caaagatcgg atagtatgtt
     6661 tgcaaagaaa aatctgttat tccatcaaga aagggaatac cgaatttaat caaagctccc
     6721 atgacaaaag gcgtaaaaca agctgcaaac atcatagggt cgctcttgat ttgcttaaat
     6781 acctgtatgg tactggataa tatccttttc atagctttac acctcccaaa cttctccaca
     6841 tatgcttaac tgtatgtcgc gcaactatgt agaggataat caacgtagca attacaagta
     6901 ccatatcaaa cgatagtaaa atgctttttc cagttatgag gttcatgcaa gctgtgaacg
     6961 gaaaaaagcg gaatatatct ggtaacttta caaacagacc aacgataggt ggaacaaagc
     7021 aaacaatttc tatcggcata atcacaatga gaaattggtt caagtttgaa atttttgtag
     7081 ccgcgataat gccaagcata gtaaagattg ctgatgtcaa agctgtacca actgcgatac
     7141 caagtaaatg attgctgccg gaaacaaatc ccaatatcac cgcaatgatt gtagaaatag
     7201 caatcaatgc gatggttttt gaaagtatat actccgatac ttttacaggc gatactacca
     7261 tagcatttaa taccttttgg cttttttcta aaaggacaat cgcccccata aaaaacaatc
     7321 ccatagctgc cgggtcagag tatatcatga tagaagcaat atccgttttc caatgtcccg
     7381 tcaaagcggc aatcccacac acatataaaa ctgttaatat aaagtagata aaatagaaac
     7441 catatttcca ttggaaatgt atatcaccac aaattaaacg tcccaatctc attgaagtgt
     7501 cctccctgta atatcaacaa aaatatcatt taatgtaggc tcactactat gaatagaaag
     7561 cagacggttt tcggaaatta aactttttaa caacttatct tctgtggttc tatcaagcag
     7621 acattctccg gttttctcgc ctttatcata gtaggtatag tgtattttgg cagctcccct
     7681 tgacataatc aaattatgtg gactatccaa tgcactgact tttccggcaa caataaaggc
     7741 tacttggtca catagctctg ttgcgtcata catattgtga gtagtaatga taatcgtttt
     7801 tccgcgtttc ttttccgcaa gaataatatc tttcattaaa cgattatttg tagggtcaag
     7861 accgcttgta ggttcatcaa ggaataatat atcagggtca tgtactaacg ctttaatgaa
     7921 attcaagcga gaacgcatac ctttggaaaa gtcagcaact tttttgtccc catcattttc
     7981 taagcctacc atatgcaata attcatcaat agaccgaggt tgcttgtcat atagagaagc
     8041 aaaataggcg agattttgtc gtgctgtgaa tttctcgtag caggttgaaa attcaaagtc
     8101 tactccaata ttttcataaa accggtttgt atgctccctt atttctgtac ctgcaacttt
     8161 tacgctgcct ttataacttg tattaagccc agttaaaatt ttttgaatag ttgattttcc
     8221 agcaccagag ggtcctaaaa aaccgaaaat ttctcctctc ccaacatgga aacttacatt
     8281 ctcaacaaac ggtttgtcag tataactaaa atacagtttt tttacatcaa tcattattct
     8341 ttcctccttt aactttatga cgtttataga tatatagtca tataaactgt aaaaaatttg
     8401 tttggccact tgcctgtcaa ataaccaaac aaaattatta ctctgctact acttgctgaa
     8461 taataccatt cactaaaaga ttttgtacca tattcaattc ttcgtcctct ttgaattgtt
     8521 ccaaacagga taaaacagaa tacagggatt ttatgataac cgtatgcgga accaaaaata
     8581 caacccctaa accttccagt atctccaata tacgaatatc actgtacata tgattttcaa
     8641 aaatatctga cgatattttt ctttgcagat agtccattaa agataaatca atctgtgaaa
     8701 gaataggcga agtaatcacc cccgttaaac ttagcataat aacgtccttt gctaaatctc
     8761 tatggttctt atactttttc tttttaacag ttgtttctat acttgtaaat aactcttttt
     8821 gtaagcgaaa attgatttcc acatatagat gttctttact gggataaaaa gcatagaatg
     8881 aaccttttga tatgtttaca gcagctgcta aatcatcaac tgttactttt tttaagccgt
     8941 ataatgaaaa cagcttttct ccctctatca aaagtttact gtttatgatt tctttttctt
     9001 gttccgtaaa tcgtggcaaa ctcataaccc ccttatgact aaaatgtttt tatcgtcatg
     9061 aaaagtataa catttactga ttatataatc aatatactat ccaagatatt tatgcaaggt
     9121 agcttccaat gcgtttattg tagtgtccgt gtcctcatta aaaatcatgt gacgattaag
     9181 ctctaaagta agtaattcct ttttcggtac atgaattaaa tcaaatactt tgttggtata
     9241 atcaaatcta aaaagcggat cgcctttggc agtaattaaa ataacaggac attgtatagc
     9301 cccattctcc aagcacgata agtcagcatt aaataagctg gcgacaaatc ttaaaggata
     9361 atagggtaaa agcatagggt catttaagca atcttgtttt gcctgttcac tataaaatac
     9421 tctgtcatag tctaaataag cgtctcctgg aaccttatag ttaggcagca attttccacc
     9481 tacacgaaag cccaactgta tcagccccat aaaacggtgt gaccatgcgg ggtattttgt
     9541 taagctcata gtttctttta atgtagtcag catgatatta tgtggaaaaa cggcttttaa
     9601 ccttgtgtcc ctacccgccg ccattgcagc taaaatccca ccttgactgg aacccatgac
     9661 agctatgttt tcaccaaaat tttctattcc gtaagtcgtt gcgtcatata cattatgcag
     9721 caaatcttcc attgtataat tttttttgat tttagggctt tttccgtgtg aaagatagtg
     9781 aatgcctatt atattaaatc ctctttcact caaaccacat agaaaattct catacatgag
     9841 agggtgtgac atagtacccg gcaaaaaaac aatggtagga ctatttcttt ctgtatacca
     9901 aatagaaagt gttatcggaa cattatttga agaaatacca acttctttat acataccaca
     9961 cgcctcctat atgactaatt tagttttata gtcatattat aacttattgc aagcagaaag
    10021 tcaatatcca taaatatatg atttaagata aaattgtcaa gaaagattta attgcttaaa
    10081 atacaatgaa atcgcttgtt agtgcagcac atttgctata gaaaaggcag actatatccg
    10141 aaaatagagc ctgccaacaa aatatcttac ataataattt tccagttgct atccttatgt
    10201 aacacaagct caaactgtga tacctgcatt gcctttgtct gattatcaat gaatttcacc
    10261 gcaaccctga ctttcacatt atccctgtca tccgtaaaca taggattgac taattcggaa
    10321 tagaggtagt ccctgccgat aggttcaagc acattgccag ccacatagta ggcaagttct
    10381 ttttctgttg ctgtcggata cagcttaaag aaagtttcca aaaatgcggt agcgtcattg
    10441 acggtatctg cgtccacgct tgcgtcggct tcttgtgcct ttggctcata gtctgatttt
    10501 tcaatcgctg gtgcaatggt tgggttctgt acgataacca tatcgccgtc tttatccaca
    10561 tggactttga cggtataggt tgctttgaca ttgcttgtct gttctccctc ttttatctgc
    10621 tgatctactt cgtaggtagc gataaaatcg ttcgttccag actgttttat atcccaaatc
    10681 agtacatttg taacagtgga gcttgtcggt atatccgtcc taatggtatc aaggttcaag
    10741 tcctgcaact cctttgtcag atagttgctg attgcctgcg tccttgcttc gatagcttcc
    10801 ttgctgttgt cccatgtgta gtaggactta cagaagttct tcacaaaatt ttcaactccg
    10861 ttggtgtcat ttagtcttaa ctgaatggtt tccgtttcat gtaccgtgtg catatcaatg
    10921 gcggtaaagt tcttatacac gccaaatgat acgctggcga taagcaccac ccacagagca
    10981 atcacagatt tcttatgtgt gcctactttc atagtgcgga ctttcgtttc ttttactggt
    11041 ttttctttct ttttaaacat ggtttccaat cctttctact gttttattct tccagcacaa
    11101 atcaagtact gttgccaata agcattgttt aaatcggcat atccgatagg gtcgcctgca
    11161 tgatacatct gagtgtttcc tacatagata ccgacgtggg ttacatagct tcctgcattg
    11221 taggtactgt ggaaaaagac caaatcgcct gcctttgcct gcgatagtgg gatatgctgg
    11281 gttgcgtcat actgattttg tgcggttctc ggtaaagata cgccagcttt gttgtagcac
    11341 cactgtacca gtcccgaaca atcaaaagaa gtgttcgggt tactgccacc atatacatac
    11401 ttccaacctt gatattttaa ggcttcattc ataacctttt gtgccagctc gcccgatact
    11461 tgattgacaa caaggtactg gttcacaagc tccacataga acatatttcc atagccataa
    11521 cgccagccac cattttttgc cacggcgata gggttcgtat aggttacttt ttgaccgccc
    11581 gacttatccc ttgcgaagtt ttccgcaagg ttgaacatat gcttttttcc gtttcctgcc
    11641 acatagccaa catagccacc gccatagtta taggactgta tcacaacatt tatatcactg
    11701 ataccttgat ttttgcagga agaaagcagg gacgcaaaat atttacaccc ctgcttgatt
    11761 gagctttccg tatctagtga gttgggtggt agtcccagac tttcagagct ttgcataacg
    11821 tcctcggctg taccgccact ttccacttgt atgattacca gcaacacatt gacatactcg
    11881 gaaataccgt tttctttggc atacttttct accataggct gatgtttcaa gacttcggca
    11941 gataggttca tacctacata attagaggaa taaccattgc ccccgtcgtc gtcctcggca
    12001 ctaatcagaa ccccaaagaa taatacgaga gaaaagagga tagaaaacag actgccaaca
    12061 atagcgatat gtcttagttt catttcttct tttgtccttt cttgaatacg gttcgtttgt
    12121 tcttctcggt attctgctgt gtatgcttct gaacggttgt tttcgtaaca cggtcagtct
    12181 tgtaattctg tcttgtggtt tcttgattga cggtctttgc tgatgtatcg ccagaagata
    12241 gtggacgttc cttgacaaca tttttcttga taggttcatc attcttcacg gttgaagcta
    12301 tggcagggcg tttgacttcc tgctgttttt ctacattaac cttagaagtg gtagctggtc
    12361 tttcatgggg acgggtagct ccgcttgtcg ctgatccgtc cgttttctta cctgcctgcc
    12421 ttgattcttg tgccttttga agttccatac gcttgtcagc gatattctgt ctatgtagct
    12481 gttgcttctt taagcgtcca gactggcggt tttccttttc ctgcaccacg ccacgcttga
    12541 aatcagacac actggacttc gccttttcct tagcagagtg aaccgcatag gcagtctgtg
    12601 tcggcatatc tttgatattt tctttgacag cagttgcctt gtccttgacc ttattctttg
    12661 tatcaaggac agctcccacg gctgaacctg ctttctgccc catgctggag cttgtatttc
    12721 cacgattgtt ctttgttcca ttctggcgtg tagattttga actggcaacg acaccaccag
    12781 ccaccgcacc agcgacacca ccagcactaa cagctcttgc aagcctatgt tccatacgtc
    12841 tagccctatg tcgcatgaac agatacggtc tgcggaatat tcgccgtccc atgctttgac
    12901 tgtcgccagc gtttaaagag aacatgctca ttaaatcgcc cagcttcatg tagatacctg
    12961 caaaatacac tatctgcaag aacgccacca taaagaacgg gtagtccgtc gatatgttgt
    13021 agaacatact ggaaatacta aaggctaccg tgacaatcag tgtaatacct gcccttgtca
    13081 taatcgtatt aaacacacgg actatggctt gttttgccat gctctcatag ctcggtatca
    13141 tacttaatag aaagctgata ggcagaaaca tagcgaaaat gataaaaagt atctggctga
    13201 acaacatcat acccgtaagc aagaatacaa atatcgtgat acccaagttg aagaacaaga
    13261 ggaagaacac catacctaaa cggtttacca cctgcagtat cgtcagattg ttgttgtcgt
    13321 tgtcctcgat ttctgttttc acgacttcct ctctggtctt gccgtcctcg tcctctgggc
    13381 ttgccgatac gagagcttcg acacggtctg ccccgatttc ctctataccc gaattaccaa
    13441 attgaagcag tagccacggc tgttgtactt gtatggaaaa taggctatcc cttatcaagt
    13501 ccacgctgtc cttgcccttg ctgtcgctgt cgggaagcat gatttttgtt cccaagtcca
    13561 gtgaagcggt actgatgtct gatgaaaagt cattcacttt cttgatgtag tcaggagcat
    13621 aggcgataaa agaagccgat aatacgaaca ccacaacaaa gttgataacg gcgtgtagtg
    13681 ccttactggt ttcccgtttt atcagtcccg tataggcaac atagatacct acgactaaga
    13741 taatcagcag aagaaatccc acataaaagc ccgaagtaga aaaaccattt tgagttacgc
    13801 ctgcaagggt ctgtatgctt cttccgatac tgtctgccat atcgttgata aagtccagct
    13861 tgtaggcttc ctgcactaca tagcccgttg cattgcttag atatagtctt atcgtccaga
    13921 caaagttggt aatacagtaa agcccatatt gcacactttt tccaatcccg tccagccagt
    13981 tccacggcaa ccacgcccag ttattatctg catagaaatc aagctgataa ttcgacagcg
    14041 gatatttgga ataaaggttc tcggtgttga tagtgtcgtc cacaagtccc gttgcgtgtg
    14101 ccaccgttcc caaaagtgaa agcaggataa gggaaagtgc cacgacaaac agagccattt
    14161 tgagaaagcg gaatatcttt tttcttgtga acacactttt tatcctttct ttcatcactc
    14221 cacctcattt cgctgtatcg gcggtctggt atcaaaggcg tgcagtaatt cttcaaagac
    14281 tgggtgtatc tgcaccacgc ccacacgtcc gtataaatct tgaagcaagc attgcccgtt
    14341 ttccaaatca cgcaatcgct tctggttgtt ctcgtcctct ttgtcaatgc tgaaaaattc
    14401 aagggtctgt tttatttcgt taatatcggt gcttctaaag gcaaatttca aaccgatatt
    14461 gtttttcaga ctttcctttg acacgtcgcc agaggactgt gtaacaaaat aaacgcctgc
    14521 gttcatggca cgtccagcac gaaccagctt gttagagagc gtttcgcctt gtgccacatt
    14581 taagaacgcc catgcttcgt caaggtctac aatcttgaaa acacttctat ccgagtggat
    14641 aaaatctaac gcaaaggtac taatcacaat cagcatggaa acggacagta attcaaaggt
    14701 cgtgtcctta tcgggtagca ctaagtcggc tacttgaatg atattgagct ggttgtctaa
    14761 gctgattgca ttttgcaccg taccgtccga gaacagcaga tgtgcaaagt cgtagtccgt
    14821 gaagctgtcg atatggtcgg caatattgca agagataggt gtatcttctt ttcttaattc
    14881 ctcaatcaca tggagcaatc ctcgctggtc gctctgggta acggcacgca ctgcctttct
    14941 aagtacgggg aacttctcgc cgtcccttga agaaatgccc gtaaggaatg tgagtatgtc
    15001 gattgccaga ctttcagcgt ctttcacatt ctgcataatc acgaacgggt caagaagccc
    15061 tgcattttct ctgtcgctgg taaggttcac gatattgatt tcatgggcga tttctgggag
    15121 cgtttctttc cagttgccac gctcggattt tgggtctaag attaccgctt gaccgccaaa
    15181 cagcacagag tagtagacaa gcaggttgtt acagaatgat tttccaccgc caagactttc
    15241 tacaaaggca gaagcaagag cattagtaac cgtatctttt acgccttgac tggcaaggga
    15301 cggttgtaga taaacattgc gtcccgtatc gacagaatag ccgatataga tacccgtgtt
    15361 ttcccctaac tgctgtgtcg caccaaagcc cagcccagct agaaaatcac ttttgacata
    15421 ctgcacataa tcgttgatgt atcgcttgct ggcaggaaga aattcagagt gaagccccag
    15481 catatcgcca gcagggcgta ccagcttgac gttcaaatcg tcgtagaagt ctttgacttc
    15541 atcacagcgt cttttcaact cgtcaaggtc tggagcagat acacggataa cataagagag
    15601 cttatacata ctttctctgg actggtctaa atccgtttcc agctcgtcca cactgtctaa
    15661 tgcgtctacc acatttgagc tggtttcact gccagactgg tatgcatgat tgtctaaatc
    15721 tttcagctct tttttcttgt tgcgaaccgt cgataacgct tttcggtttt ccacgatttc
    15781 tacattcatg ctggtatcaa cgggaaaagt aaactgctgt tgctggaaat agaagatttc
    15841 actggacgga aaatcaagct cgccgacaat cgcattgaca gtaaagtagg aaacgtagct
    15901 ttcgctgtcc tcatgttcca agcgtaaatg tcgctggctt tcttccacaa ggcaacgggt
    15961 cggacgtatc aagtcataat gcgttatcag cgtttccttt ttcagtttct tcttcggtaa
    16021 gctatactca taatcttcat aggcgacacc gtccctgccg tagatgtgtt caatcagata
    16081 gccgaagtca tttttatcta agcgtcttac tttgaagcgt cggcttattt tattttccaa
    16141 cagcttttcc attttcatgt agcggttgat ttcatcattt ggcatggaaa caaagtcatt
    16201 catcagcgtg tggttcactt catggataaa ctccttgaat gtgagaaacg ccgattgctt
    16261 cacgctcttt aggttcatgc tctggtctgt taccatgagc ttgaagccaa gaaaaaagcg
    16321 gtagtccact tgattgtccc caatcataga tactaacgct tcggtctgtt cgtctatctt
    16381 ctgataggca acgtctttta gtcgtcccgt aaccagcttc tttgactgtt cttgtatgct
    16441 tcggcttgag ctttctgtgg caatctgcaa agcgtgtatc ttgccctcac gggattgtgc
    16501 gattagctgt cggaagctgt catgcacaat gaatttctgt tcagcggata gaaaactgta
    16561 attgtaaggt atcagctcat agtaggcgaa cacctcattg tccttgttcc agacaaggtt
    16621 gttgtcgata tatttaatcg ggaacatagc tcacactcct tactgccgta atagcttcat
    16681 gtagtacctg cttatccagt ttcacggctt ttcctgcata agtaatcttt ggtcgtaggg
    16741 caaaggttat ctgtgatttc aaaaagctgt acggcttctt gccgtcaaag gtcttttgcg
    16801 acatgaacca tgtaagagct acgggaatac cgaagtattt taaaaatgcc ccctcaatca
    16861 tggataaggg cggtaagtcc ccaaacagaa tgatgataaa ctcggttatc acaaaccatg
    16921 taatctgtgt aaaggtaaca ggaaagggca ggttaaagtc attgattgca tacaagactt
    16981 tttccacgtt ccagataccc gtgtagcttt taatcttttt cacgtttttg tttcaactcc
    17041 tttcgtataa tagaaaagga cagccgtttt tcagactgtc cccaatagaa aaagctgtca
    17101 gaagcaacaa tgcttgtcgc tgatcttcca gcttcttacc acggtatctc acacataccg
    17161 tatcttgttt caataaaagt tccctcaaag gataaatccc tgccgtatgc ttcatagtca
    17221 atatagttct gcaaactagg gggaatatcg ccaagtgcct gcaattcatc aatgaagtaa
    17281 taggcaacgt cggtcatatc ctcacagcca gcgtataaaa tcatatcgtc cctatggtcg
    17341 tacagttcct ccaaacttcc ataatttgat acaaattcgt ccaaactgtc cgtgatgtag
    17401 tcgggaagct cacatatcat ttcatacatt tcattgagct cttcaatcga gatatattcg
    17461 ccaatctcaa tgggaaagtt ttccgtatca tgtacggcgt attcttcgta ccgttcattc
    17521 aagccgatac gctcggcaac atcttcttcg tcaatcggaa aagagaacca gtcgccgacc
    17581 agatacccct cattgtattt cccaagatta gcgatatata cacgcatatc ctctaccata
    17641 gaaacacctc acttctacgg cagttcatag ataccgtggt ctgtttctat aaattctccg
    17701 ttatcatcaa gatactgtcc gtaggcttca taatcaaagt aacgggtcag gcgttcctcg
    17761 atggcagaaa aagcagggtc attgtccaac aaatgccttg ccacatcagc catgttttta
    17821 caccatgaat aatgtatcac atcatggcgg tgctggtgca gttcgtcaag gctggtaaag
    17881 taacacatca gctccccgta gtcctcttgt aaatcggcag gcagactttc aaaggtatgg
    17941 taaaggtcat tcagtttttc aatggtcgca tcttcgccga cttcatcagc aaagggcagt
    18001 tccttttcaa cgatatggta atcttcactg tcgataggaa cgcctatctg ttcttccagt
    18061 tcttcctcgt caatgggaag tgtgaaccat gcggaacgga tttcttcaga agtgtgtagt
    18121 cggctttcga tacagacacg catttcattc ataggttttc acgtcctttc tttcatgctt
    18181 cagctatgct agtgtaaggg acaccaaaga catagcctgc aaaatcttct aattgtttct
    18241 gcggataatc ggcaaggttc agtcgcttca tttcctgcca caccatacgt ttatgatgtg
    18301 gtaaatctga aatgtaggta cagccgatac ttgcctgcat atccgaaaat atatctttca
    18361 agcaatcact ccaatcttaa atttaggtat gaaaaaaagc agtcaatcgt atagactaac
    18421 tgctttgtat atagctgtta aattgagttt atcaattctt gtacttcatt aaaaaatctg
    18481 gataaatgga atccatctgc tacggcatga tgtatattca ttgtaagagg cattatatat
    18541 ctttcttgct ctaattcata tttgccccaa gtaataactg gtgcaagaaa ttttccctcg
    18601 tcaaaaacat gaacatcaaa atgattatat tttacccacg gtaaacaaga tacatcaaaa
    18661 aagttcaaag attgattttc cacaaatgca cgttctgttt tatacttctc cctatctaat
    18721 ataaaacgtt tatgaaattc aaatatgcta tcagaaaaat ctgtaactat ctttgtgaaa
    18781 ttttcatctt ctttatgaaa ttcagtatag gacggagaaa tataatccca cttaattaaa
    18841 ttcccattat tatcccaact atatttgaac tcatcatgtt cattaacaac ctttgaaaca
    18901 gcccatatca tagctggata aaattttaaa tcatgcttct ttgaaaattc aataaacttt
    18961 gttacatcaa tatctacggt taagctcata acaatacgca tattatcaat gtagctttga
    19021 aacaatttac ctctattcca tttattcaaa tcaatttttg tatatttata ttccatgccc
    19081 attctccttt acattttgaa atttgataaa atgtaaggct ctctggataa catttcactc
    19141 catacaagtc tattccatta agccttatat ggagataaaa caatacacaa tttcacaata
    19201 tcactcctta tcaaaaaaac tttcgtttat tattttcata tctttattat atcaactatg
    19261 tttgagccaa gcaatgaaat tcattatgct gtatttttat ctgtgtacca ttccgttacc
    19321 ccctttcccc ttagcccact cccaaagtgg gaaaggtatg tttgcgtatc cgcaaaccat
    19381 aatgaaaaag tacggctatg cgccgataat cttattgaat agttctaaga gtacgtcttt
    19441 gacaccgcct gcattgaata ccaatccaac agcaactaag gcaaccacca agaagccgat
    19501 aagttttgaa aactcacgtt taaaccctaa gtagatacca ataaccacaa tcgccataag
    19561 cactaagctc tgggcgttgc ttaaaaacca tgtatataaa ttttgcccga aattcattta
    19621 tttttcctcg ctttctttta attcaatcat gtgtcggtca gcttcctttc cgacactcat
    19681 aatacacatc agaaccacgc cgatacccat gccaagtgat accagcagta agtccttaat
    19741 caattcccac atcatcaatc actccttttc tttttctatc agttcgtcca ccgaagccgt
    19801 ctgctgtctg attatctgct tgtgcttatc tgtcagcttt gcctgctgtt caatggtctt
    19861 gagatagtcc atctgattgc cagcgtctat ctgtttcagc attttcaagg tcggtgcaac
    19921 ctgtctttgt aaccagttca gcgtcctttg cagagtgtaa ggctctggct ttgtcgtcag
    19981 cttcacgggc ggtcgtccct cgccaatgaa ccaagaccag cgggcgttgg ttttccagtc
    20041 gctttttcgc ttgttggctt ccttatcggc aaagcggata tactggttga taatagaaaa
    20101 tgccgtcagc tctgcgtcgt agtgggtcag cagctctcta atggcatagt aggcgtgctc
    20161 atttttcaaa cgtatctcaa atcggttttt aatggggact tcctcaatcg gtatccctaa
    20221 ttttgaggat tgttcataat tcttttcata gacacagaag tacacttcac tggtaaatga
    20281 accaatgtaa agcgtatgtc ccatgccgtc cttgttggct tcgttgtgct ttaccagctc
    20341 cccagaacca tagttcttga agctacggaa tttagaaata cattcctcgt tcttgcattt
    20401 ctctatcagt tctggaatat ccagtaagcc cgttctgtcg ttgatagcta ggtcgatacg
    20461 cttcatcaca ccgccatcaa ctaatgcgtc catgaggaag tcataccagc ttctttcctg
    20521 tgccagcaga tagctttcaa actgacgaca gccttttcct ttcagttcca gcaggacacc
    20581 tttttccttg tcttgtgaag tgtaaacgaa cacgtccccg atatagtaat gctcggtgta
    20641 cttgtaatgc ccgaaatctt cgtgaagcat ataatctata ttcagcttta gaatgtcctt
    20701 gataacgtgc tgtatatcca gcgtgggaaa tcggatacgc acataatcaa agagcaggaa
    20761 catgggagcg tcgggattga atttttccac cgcttccagt agtttgtgct tcatatcctc
    20821 ggtcagtgct accttcccag cttcgatacg gcttagatgt tcacggctga taccagccat
    20881 gattgcaagc cttgtctgcg atacgccata atcactgcgt tttgctttca aggtgttcag
    20941 aaaatcagta tcattcagtt gtcatacccc caatcgtgat attgttgtga ttttgtgata
    21001 ttttcaagtg attatcacaa ctagctaaaa actaagaaaa tccttattcc tagcggactt
    21061 ttcaaggttt ttgaaccagt ttccagcgta attgtgcccc tctgttagat aatgaggggc
    21121 ttatatctgc tggcgtggct aacgccacac cagcaacggc tagtccgtgc cgtcgccttt
    21181 cgcttcgcac gtcgccgtcc cgtcctgcct tacgaatgca agagagccta tggtctgcaa
    21241 aaaatcatgt cctttcggga ctaaaggcgt gtaaaactca cttatgacac ttgttcccac
    21301 atcacaatag ccacgcccct tgatacgctt ctggaaaaac tgttttttca catcagaacc
    21361 aaagagcata ccgtaaccca attcgctgat acgccccaat ccaacacgga aattgaaatt
    21421 atctctgata ccgtccgaga aatattttgc gtctggacgc tggcaggcaa caataaggaa
    21481 atatccagct tgtcgtccca acataacgat tttctttaac tggctaagta aacttacgct
    21541 ttcctttgtc cccagcattt caaaaaacgc cacatattca tcaaagataa gaaagcaggg
    21601 cggtaaacca agataggcgt agttttcgcc cgttttatag tctgggtgtt gcttcatttc
    21661 ttcgcttctt tgtaccatgc cctcataaaa ggcattgaca caatcaatca tatcttcttt
    21721 ggtatgatac acatttccca taactgtacc taagtctgca aggtcagcgt tctttgggtc
    21781 taagatgtaa aggacagcat tcgtatgtag cagagcttca ataagcgtca gcagaaagta
    21841 ggtcttaccg ccaccagtcc caccagctat cagagcgtga gggagtacgt catattccca
    21901 gacaagattt ttcatcagcc taagacagcc gttttctgct ttcacttcgt caatggaaat
    21961 acggttcgct atcatgtcat ataaaagcgt gtactcaata tagccgtcat gcaaggtctt
    22021 gtcggtcagc tcacagtaca aaccgctttc cagcttatcc tctaatcgca aaagctggtc
    22081 ttgatatttt cctaatgtga tttcacagtg aatatgaagc aatccgtttt ccatttgata
    22141 ataaatcttt ggaaaccaga cgattttttc ccttgatctg ctttgcaggt cagtaaaaaa
    22201 accgctgtct tgtacggtat ctgcttcata ccacttgttt tccagtatca ttcgtgccag
    22261 cttttgacgg tgcaggagct ttttgaaact gtcataacag aagcggtaat acagaaaagc
    22321 gaccaatgca caaataccag tcgctatcaa tatggttatg aagttgtagg gggaaagcgt
    22381 caagccattg tccaataagc tgaaatgttc ccagtcggta cgcatgagct gtttgatatt
    22441 cagtagcagg agaaccgcca caaatacaaa cagaagcgtc cctatggaaa agtggtagac
    22501 aaggttcttg tctctggctc tgatacggtg tcctttattc aaaatcattc gcataaatca
    22561 atcactccaa tcttaattta agtatgaaaa aagcagtcaa tcttaaaaga ctaaccgctt
    22621 tgtgtgtatg aatatgaagt tgttacattg tagggtatgt tcattatata tgctttgttg
    22681 ttttaactct tgattgtgca atttcttcaa atagctgttt ttcgtttagg tctttaaaaa
    22741 ttcttttggg aattaacgta tataatcgtg gtgcttgaat taagtaataa aaatcatggc
    22801 tttcccatag tgcagagtaa atgtcccact tcacttctga gtcaatgctt tgtgttttaa
    22861 atttaatgtt ttccttagaa aataccagcg tatattcctc atgatatttt gcagtttgtt
    22921 tgaatttcag tataggcatt aggatatata aatagcttcc caatgcagtt acaacaatta
    22981 tcaatccaaa tattaaaata ctaaatacgc taaaagagga gaacagcata taaacgactg
    23041 acagcaacaa aaatacagcg actaaagcaa tatcatattt atgtatagtt ttactagaaa
    23101 ttaaatattg cctttctgct tttatatatt cactttgagt atattgaaat cttaactcta
    23161 ctgtttccaa aggtattccc ccattcgtca tataaataat ctttgttaca atttcaaatt
    23221 tgaaaatcac tttttcttga aaagtttcag ttttatattt ctcctttcag caatcttctg
    23281 aaacacctcc accacataca agcattgtgc cttaaatggt agtaaggtca attcgtcatt
    23341 ggattgtatt tgtttcattg cttcttgtaa ttctgaaagt tctaataaat tgactgccac
    23401 acaaaagaaa gtctttctac gcccgtcatt atagttagaa agtaagtaag aaagaatttg
    23461 tgttttttcc tgctgttcaa gattatattg ctcaatgcct atgttttttg ctctttctaa
    23521 atctgctttt cgccgtttat gcgtgatgaa agaatcataa tcatcaatgt gttgatattt
    23581 ttcgcatgga tattgtttgc attcatagca atattcaatc tgtccatgtt caagactaca
    23641 ttttgcaatt ctgcatgatt gattaccatt gccacaaccg ccacagtaat ttcccaaaag
    23701 catagggcat agtccgcaat tcaatccgca aagagaaaat aattgatttt tgcgttcaaa
    23761 tcctttcata gtattagtct cctaactttc aatttatcgc atacaagcat ttataaattt
    23821 cataggtaca tccatacgtt ctgcaacttg ttctggtgtc attccactat ttaagaaacg
    23881 cttgcacact atcttcatgt tttctccaac ttcgataata tgtttatctg ggtcataaaa
    23941 gcggactaca cgctgtcccc atgaatgttc tataataggg tggacatatt caatatcata
    24001 ttctttcagc ctatcagcaa atttatcaaa atcttcttct tcaaaataga cttcaaaatt
    24061 gttaccacca aaagaaatat cacttgtacc gataaactct ttgtatgttt cacttgtctg
    24121 taaggctaat ccacctgtta aagttttatt tgccccaaaa tccataatga cataaagtcc
    24181 aaaaaccttt ttataaaact caactgattt atctatatca gttactacca acatagggtt
    24241 ttttaatttc atttttgcta cctccacaac ttccaatttt ctttatgtcc acatgacagc
    24301 attttcatat atccgctatt ataagaaact atccatttgc taatggtgtg gtaataaact
    24361 actttctatt tggttttctt tttatcctca aaagtttaac aaaatcgtca aacaaagttg
    24421 tatctgttgg ctcaaacatc agccattttc cgtcatggta agtttttgtt tcatcataaa
    24481 ttctctgaac ttcttttgaa taattatctc tatatgtatc gaattttaac cgttcatctt
    24541 tacctaagat aatcataaat cccacacaat tttctctagc atataaggca cataatgttt
    24601 tgccacctcg acgatactta tattcataat tccatgcttt gccaccttta ttccatagac
    24661 attccatttc atacttttca tcaatcaagg cacacaattc attccataca ctatataatg
    24721 attgtccgac caaagcagtc atttcctctg cattaggtat tttatctagc atacacattt
    24781 ctcctttata agtctaaatt aactgtttcc acatccatat tataacagtt gtttatatct
    24841 cctacaatga aaaactagtt tgtcagctta ctttttctgc tgtccctgcg gagcgttgtt
    24901 ctgcggattt ccagcttgac cgcctttgtt cttcaataca atatcatcag ctttgatgta
    24961 ccaatcaacc gtagtccctc taaagttggc atttgccacc gtatcagcta cgggattgat
    25021 taactccact tccgcattat aaggaaagtc ctttacggga acatcagcgg ggattgacac
    25081 ttgtatcatg cgttcctgca cactacattt caaatcataa gtacgacgct taatttcatc
    25141 acttgtcgtt ccgtcctcat tttctacacg cacctcatgt cgaagtgcag agaatttcaa
    25201 tactccaaaa gttttttcgt tatctaatac aattccattt gttaatctca taatcaaata
    25261 cccccttatt tgctttctgc tggtaacata tcatcagcca ttaaaatgta gtttgtaaat
    25321 ccacgtcctt tgacgttgta accctctgcg gtaatgcgtg ggttaatcag ttttactttc
    25381 tgctctggct taaaatgctt ctcgccagct tttgcaggca atacaacgat aatgtcgtcg
    25441 gctctctgaa tatccgaata caagttgtaa cttcttgata cgagagtgta acgcccattg
    25501 atacgttgct ggtctacttt gttttcccct gcaaattcca agtttccaaa agtctgtgcc
    25561 acattcggca cgatatattt taattccata ttattttacc tcgtttctta ctttaagttt
    25621 gattgatgtg tgtattctgg catttaggaa agtgccagca agcccccaga tagtaaaggg
    25681 taaataaatg ctaacgcacc cttgactatc cgtgttcttg caggtaatcg gcagacaagc
    25741 cagaataggt atagtctgcc tatctaagct atggcggaga gcgtgatttt tcttttctca
    25801 tacagctacc gccttatgat ttcttcatct tacggtgttt gaaaaagtat gtaccagcca
    25861 gcccaccagc agaaacaaac atcataattg caaaggcaag gatatttgta ttgtcgcccg
    25921 ttttgggact gtctgttttc gtaggtgtat ctggtgtggt tggcttctct ggttcttctg
    25981 gggtaggtgt ttctggtact tccttgatag taactgtctg tccgtcgtcc tcaatgtcct
    26041 tgtgttccgc aactttgata ggttcgtctg gattgcttaa atcgtataat tcctcaaaag
    26101 ttacaagctg tttaccgcca agattggaag cgtcaaaggt aaactcgatt ttaacttcca
    26161 tagtttcgct gtcagccgta aagatgtagt cattctcaat acgcttgtca ttgatgataa
    26221 gctctgcatt ttcttctttt aacatctgcc agcctttcaa ctgatatttt gtccctttgg
    26281 taagaccgtc taatttaact gtatcagtga tagttacgtc tttcccagca agaatagtct
    26341 tttcgccgtc cttgctggta gcagtagtat ggatagtgat ttctttttcg tattcatcag
    26401 tcagcgtacc taaatcaacc acaaccttat ttctggaaat gacaatctca aacggtggaa
    26461 taagtttgaa acctttgttg ctttcacaac gtaattcttc aatgatgtaa gtatcataaa
    26521 gcaacgcacc tttgctgtcg tctggttcag aagtaccaaa ccacacaccg tcctcgcttg
    26581 tttttcctgc attggtattg tgcttgtggg aagcccaatc agaagcagta gagaattgtc
    26641 cgttatcatc agttacaaca acatgacttt cgcccgtcgt cttgcttgtg atcctaaacg
    26701 gaacatctgc aagacgcttg tgcgaacctg caccaatttt tacgccctca atatcgccac
    26761 gtttaatctg gttatagata gagtgggctt cgtcagtcaa atcaacgatt tttccatttt
    26821 ctgtgatttc aaaatcaatc ggctttgcac cgtcagtcaa atatccctct ggcggttttt
    26881 gttcagacaa tctgtatttt ccgtaaggta ataggtcagc agaagtagaa gcgataccct
    26941 caatgtcggt atggattgtc tttaacactt catttttctt gtataacttg ccctcaacta
    27001 agacggcatt ctcatttaag gaaatgattt caaaggcggt atctttcaaa gtcgcaccgc
    27061 cttgagcttt cgtgtctttg gtttctaaat ctcgtttctg gattttcaca ccgccacgaa
    27121 tgactttatc agaaacatgg tattgattgc ttccagataa tacggcaagg tcgccgtcct
    27181 ctgtaatctg tgtcagatac attcctttta tctgttcttc gctaccgtca gcctgcatat
    27241 atgtaccctc taacaagtaa cccgacggac tttttgtttc ctcaacagtt agtgttccta
    27301 atggaagtac gtttttaccg tcctgcgtat agaagctgtc ccaagatact ttatatttgt
    27361 cagctaaacg agtaatgtaa tggatagcac cgtcgctgtc tttttcagcg atagtctttg
    27421 ttacccatgt tcttgtaggc tgtgctggaa gattgttttt gttgtaatat ccagcgtaga
    27481 agttccatgt aaactctgct ccctctaaag aagcgtttcc ctgcggattg gatttctgtg
    27541 tttccatgtc aatcttgaat agctcaatca aggtatctgt tacttttggt gtatcagata
    27601 cttttaaagt cgctgttttt ccaacttcca cagataaaga gtaaactgtt ttatcaattt
    27661 taaatcctgc tggtgcagaa agttccttga tatatactat agtggctctt acttcaacgg
    27721 cttctgtatt tccgctagta tcagtcgtaa gggtggtaag ctgtttcgtg cagtctttat
    27781 cagaatacac accgtatgtt gcaccagcga ttgaataaat cccgttgccg tctgtaatat
    27841 tggcattggt ggaagtcttt tgaagtttgg tatttccgac agctaacttc gcccagaatt
    27901 gccctaactc ttgaccctcg ccagagtaga tatatccgcc acagtcataa cgtcctttgt
    27961 tttctttcac aaaggctttt gctcctgcga atacttcatc ttgtacggct tttgggattt
    28021 catcatagga agctcgcaca ttatcccatt gccagtcagg ctgaacactt aatctctgcc
    28081 agacaacaag ctgtcttaat aggtaggcgt gtttactgct tattccgctg tggatgtctg
    28141 tgtactgttt cacatactca atagataagg cgacgtcagc tatctggtcg gcactcatac
    28201 gggtacttgc gtcagctttg gtcttatagc cgtttttaaa ggctgtgttg atgtcgatac
    28261 aataagcgtc ctcaccctca acggttaaat gtccctcatt aaaggtagaa ctgatagaac
    28321 cgtcattcat tacttgttct acgatactga cacgctcttt actttccgtc caatactgtg
    28381 tattagacgc atgaaccgtt gaactcggta aagcggtaac gacagttgca aaggcaagaa
    28441 agcctgtaca caatcgtttt aatatctttt tcataattct aaatgctcct ttcattttgg
    28501 tagtaaaata gccgtccact aggaacggct ggaaatagaa aaggaacgct gatattgtgc
    28561 gttccgtagt ctatgaagta ttcaattttt cttgtttcaa tactgatgtg ctgtaccgta
    28621 tctttgcata tctgggaaat aggacgtatc aaggctcatt caatcgtagt aaattagtag
    28681 tattttgatg tgtttagctc cttgataatg ccgatagata cagtgtttta gcggataatc
    28741 aaatttttag tgtgtttttc tgttaatagt tttctaaaga tgctctattt ataaattttt
    28801 atcaaagatt ttataaataa ttgtatttaa tatacaaaat atatataaat attgatgttt
    28861 tatatataaa gttgtatatt tttttaagga tataaagtaa aaaaatatac agtatcaaga
    28921 aaaaaagata ttgggtattt aaagtaatac tttatttaat tttaagtaaa tcgggtatct
    28981 acatatatag atactaattt caaagaatag gagggtattt atatggaaat attcgcaata
    29041 ggacattcaa attatccata tgataagctt attaatatga taaaaaaata tgacataaat
    29101 tgtgtagttg acattagaga aactccatat tctaaatata atattcaata caataaagag
    29161 gcatttaacg aatctcttag aaattccgga tttatatata tatacatggg aaaagaattt
    29221 ggagctaaaa gaaataataa agatgtatat acgcaagaag gttatgcaga ttttgagaaa
    29281 gtagcaaaag aagatatttt tttaaacgga atagaaagat taaaaaaggg ttgtcaaatg
    29341 ggttatagga tagttttatt aggagctatg caagaaccta taagatgtca tagaagtatt
    29401 ttggtgggaa aagtattaaa taaagaaggt ttcgatgtaa aatatataat gcatgaagga
    29461 aatttggcat atcaggaaga tatagaggaa tcattattgg ataagtattt tagtgataga
    29521 gagcaactga gtattgacaa tttattaggg agtgcattaa cgagagaaga aatgatacaa
    29581 gaaggttata agctagctaa taaagaaata ggatatagaa ctgagaaact aggtaaataa
    29641 aaatatacaa gtagataaaa tacagtactt atcttaagta aaataatatt atgaatttat
    29701 aatagctagg catgatgtgc caattaaaaa tattctagtt atttaataat atcattaaat
    29761 ttagggtatt ttttaatagc acatcatgtt gcagttttaa aaaataaaat ctctaatatt
    29821 gccataatca actgttctat taagagtagg atgactagat ataaatctaa ctgtaatttt
    29881 tgaatttaac aaacaaggat ttgaaattaa aaatactcta tctccattga caatagaagt
    29941 aatagctact ggcaaaatat ctacaaatgt atcatatctg tttttagcaa tttgataagg
    30001 ataatttcct acaaaaacaa atagatttaa atcatatata ttatcagtaa accaagccca
    30061 ttgaccataa actttgtcga tattcattgt gcctaaacca agtgtatcaa agtatgttgc
    30121 tatagttaaa taaatatttt ccatgttttc taaatatgaa acagtatatc ttctgaaacg
    30181 tatgggtgct gtggaagaaa taggataaac catatttaca tttagattat ttgcatttaa
    30241 attaaccaaa gtatcacatc ctaaaattag tctataaaat acaatattta aatggatgcg
    30301 attttgttac atctaaagtg taatatttta tatattgaaa aagtggtaaa agtttggatg
    30361 attaaataat attataaaaa atatataaaa tgtacttatt gttattgcta cacgatagtg
    30421 atacaatatt aacgaaatat agctactttt aataataacg gaaaatattt atattaaatt
    30481 aataaatatt ttaaatgtgg tatccataaa aaataataaa cataagataa ttataaagat
    30541 atactgtgtt caaatgatat taaacaagat ttatattatt tgaaagcagt atattataat
    30601 gcgaacaata caattctaaa ctttgcattg tcaatttaca gttcgataaa ctaattaaaa
    30661 attaaattta tataaagagg gaaaagagga atagggatgt ttataaggaa aaatgttata
    30721 aagttagcaa ttcctataat gatagagcag acgtttgtca tgcttttagg agtatttaat
    30781 acaataatgg caggtcatat tggggaagaa gctgtatctg cagttggaat ggttgattca
    30841 ataaacaata tatttatatc tgtatttgct gcattatctg ttggagctac tgtcgttgta
    30901 gctcaacaaa taggaaaaaa agatagtgaa aaggtgaatg aaactattaa gcaggctcta
    30961 gtgtctggag taatattatc ctttacaata acaatattga tgtgggtttt tagaactggt
    31021 gtaattaatt tattttatgg ttcagcagaa gaattggtaa aatcaaatgc aaaattatac
    31081 atagagttta cattatttac gtatccattt attgcgacac aacaaatagc aaatggtatt
    31141 ttaagagggt gtggagatgt aaagaaacct atgtatgtga ctatgtttat gaatatagta
    31201 aatgtaacat taggatatat acttatatat ggtattgatt taaatcctct aggaataaat
    31261 ttgcaaacac catcctatgg cataacaggt gcagctatat ctattgctat agctagaata
    31321 attggatgta tagtaattat aagagcttta tttaaaggaa atgaatttat atctatgggt
    31381 aaaatatttc catttaagat tgatgttgaa actcaaaagt ctatatttaa tatagggata
    31441 ccagctggag ttgaacaact actttttaat gcaggtaaat tgattgttca agtatttata
    31501 gttactatgg gaacatcagc aattgcatcc aatgcaatag gaatgtcaat tgcatccata
    31561 ataaatgtaa ttgggaatgc tttagctttg tctgctacaa ctttggtggg acagtatata
    31621 ggacgtggag atattaaagg agctaagagt actttattat atttaactaa atttgcaaca
    31681 atttgtttat ttatagtagg agctatattt ataccaattg caccctggat ttcaagtatg
    31741 tatactcaaa atgctagtgt aattgacatc tcaacacaat taattcgaag tgattgttta
    31801 gctatggtaa tatggcctat atcctttgta ttatcagcag ggctaaaggg agccggtgat
    31861 actagatata caatgatgac tgcagtaata ggtatgtgga tttttagaat ttttacaggt
    31921 tacgtattgg gggttgtatt agaatttgga gtgttaggaa tttggatagg tatgtatact
    31981 gattggcttg ttagagggac tttatattgt ttaagattaa gaggaacaaa gtggctaaaa
    32041 cacaaagttg catagaatat atgaaatcac ttttagatgg ataactctat ttagaagtga
    32101 ttttttatgt agttattatc ataattataa gtatgatata taaggttatt aaattacata
    32161 aataaaggct ataatagtat ggatattata aattatatat tgagcagaat tacataattt
    32221 ggcgataaat attagaaata tatatctata gaaaataata tatatgggta tattattaaa
    32281 tataaaaaat attaggtatt tatttaataa taaaggtggg tattgttatg ataaataaaa
    32341 taggaaaaat aactctctat gtaaataatc aagaggatgc aaagttgttt tggacagaaa
    32401 aattgaactt tgtagtaact tatgaaaagg aaatgggtcc aaatatgaaa tgggtggaag
    32461 tagcaccaag taaaaatgaa tttacaacat ttgtgttgta tgataaaaat ctaatgatga
    32521 agcaaaacaa agagataaat gtatctcatc catcaataat tttaagtaca agagatatta
    32581 atggaactta tgaacaaatg gcaaataacg aggttgaagt tggggaatta atggagatgc
    32641 catatggaag gatgttttct tttaaagacc aagatggaaa tgattattta gtcagagagg
    32701 ataaataatt ttacaaagta ttaaatttac tcaatatctg atataattag agacaataat
    32761 tattataaac tagtctagga ttagaattat ataattaaaa attaagtgta aattttgagt
    32821 agaggtgata aaatgtttaa gaaaatggca gtactaaaag atatagcaac taaaataggt
    32881 cgtaaaaaag cgtatgaact attagaaatg gttgaaggta atgatgcctt tgtagctgag
    32941 gtaaagataa aaaagaatgg aatagaatct aaaaaagaag aaattatgtt aaaagataat
    33001 caaaaaataa tattagagta tatagaaggt taaattttaa atacatataa gttgatatac
    33061 taaatttctg agatgagttt acataaaact catctttttt acttttcaat aactttgttt
    33121 tattatttaa tatacatttt atctgcttag agttgctgat atataaaaat tactgatata
    33181 ataaaagaat ggatattaat gtaatatttt atagaaaaga ggggtattat gcttgaaata
    33241 aaaaatcttt cctttaatgt tgagtctaac aatgaggaac taggaataat aaatgatgtt
    33301 agcctttcat ttgagagggg aaaacttatt gttatcacag gtccaaatgg tggaggaaaa
    33361 tctacaattg ctaagcttat tatgggaatt gaaaaagcta cgagtggtca gataatttta
    33421 gatggagaag atataacaaa tcttagtatt acagaaagag caaaaaaagg aataggatac
    33481 gcatttcaac aaccaccaag aataaaaggt atgacagttg aaaatttact tacacttgct
    33541 catggaaaac cattgtctac tgatgtatgt tgccaatacc ttacagatgt tggattgtgt
    33601 tcaaaagact atttaaatcg tgaagttgat aactctcttt ctggagggga aatgaaaaga
    33661 attgagatag caactctttt tgctagagat ttaaaggttt ctatatttga tgaacctgaa
    33721 gcagggatag acctttggag ctttggaaaa ctcaatgaaa gttttaagaa aatacatgaa
    33781 gagtctaatc agactataat cataatttct caccaagaaa gaatattaga gttagctgat
    33841 gaaataattg ttctacaaga tggttcagta aaaagccatg gaacaaaaga ggctatatta
    33901 cctgaaatca tgtgtcaagt taattcaagt tgtgaattaa tgaaagacat gaattaatta
    33961 gaaaggaagg caaattaaat gaacaaaata gatttaaatc ttttagaaaa agttgctgaa
    34021 cttcgtggaa ctccattagg agcatacaat atacgtaaaa atgggcaagg agtagagaga
    34081 cattcaactg aaaatgtaac tataattcct aaaactgata aacctggaat agatattata
    34141 gtaaagccaa atacaaaagg agaaaatgta catataccag taatagtaac agaggctggt
    34201 gtacaggata tggtatataa tgattttgaa attggagaaa atgcagatgt tgttataatt
    34261 gctgggtgtg gtatacataa ctgtggttgt gatgatagtg aacataatgg tatacataga
    34321 tttttcttac gtaaaggagc tcgcctaaaa tatgtagaaa aacattatgg tgaaggtgat
    34381 ggagaaggaa agagaatttt aaatccagtt actattgtca atatggatga ggattcatat
    34441 tgtgaaatgg aaacaattca aattaagggt gtagattcaa ctaaaagaga aatggatgca
    34501 aacctaggta aaggagctaa aatagttgta tttgagaaat tattaactca tggtaatcaa
    34561 gttgcagaat ctaatatgaa ggttatctta gagggtgaaa actcttctgc tcaagtagtt
    34621 tctcgtacag ttgggcaaga taattctaag caaaagttta atccttgtgt tattggggat
    34681 tccctttgtt ctgcacatgt tcaatgtgat tcaataatta tgggaaattc tcaaattagt
    34741 gctatacctg aaattgctgc aaatcatcca gatgctcttt tagtacatga agcagctatt
    34801 ggaaagattg caggagacca aatactaaag atgatgacat taggtcttac tgaagaagaa
    34861 gccgagcaac aaatacttaa ttgcttctta aagtaaatta aagattttat ttaatttaat
    34921 ataattaata tagtataata tagtgaataa gtctaaaata tttttatttt taggcttatt
    34981 ttctttatgt aagaaaagct attagagaaa ttatattgta attaggatgt ggaataaatg
    35041 aaaaatttac ttataagaaa tgggacaata atatctccaa cagatggtat caaatttgaa
    35101 aaaagagata tcttggtttt acatgggaaa atatatgcta ttggattgaa ccttaaagag
    35161 aaaataagaa aagaaaaatt acttacaaat aaagagttcg agataataaa tgccgataat
    35221 atgtatattt ccccaggatt tatagatgtt cacacccatt gttataagag aaaattacct
    35281 acaggtatgg attctgattc aattggaatt gaaaaaggtt ctacagttat atttgatgca
    35341 ggtacagctg gtccctcaaa ctactatgat tttaaaaaaa agtatatgga tgagtgtaaa
    35401 acagaagtat attctttttt aaatgttaca aatgagggac taaatatatt gaatgaatca
    35461 acttctttag atgttataaa ttttgacaag gttgagtcaa ttgtagaaaa aaatatagaa
    35521 aagataaagg gtataaaagt aaaagcgagt aaatttcaat ctaatgaaag tggtatagat
    35581 ataattaaga aatcaaagca agttgctaaa aaattaaatt tacccttagt ggtatatata
    35641 ggagagtatc catcatatat agatgaagta atgaatattt tgggaaaagg agatgtggtt
    35701 acaccagtat atggaaatag tacaaatgga atccttaaag aatctggcac attaagaaaa
    35761 tcagtaataa atgcaaagaa tagaggagta ttgttcgatg tatgtcatgg agtggaccaa
    35821 tttgatttta aagtttttaa aaaagcaata aagcaaggtt tagagcctga cctaataagt
    35881 actgatatgc atataaaaaa catgaaagac gtaaactatt ctcttttaaa tgttataaat
    35941 aaaattatgg aacttgggat atccctagaa aagtgtatag aaaaagtaac tgaataccca
    36001 acaaagattt tcgatttaca tggaaataaa ggcagaataa agattggagg agaaggtgat
    36061 tttacaatat tcacaatgga ggagtgtaat gatattataa aagactacaa taataatgaa
    36121 cttgttttaa ataaaaaatt aagattgcaa tatactgtaa aatcatggat gaaaagcagt
    36181 gaagtttata gacatggata cgaaaatact ataataaact aaacaatagt gataaaataa
    36241 taaatatatg tttaaattgg tatatattgg ataaatatct aaggaaacaa caattaaaaa
    36301 ataataattt taggggaggt attttagtat gaaagcattt gttgataagg atgtatgtgt
    36361 agcttgtgga gcatgtatag gaacatgtcc agacgttttt agtatgagcg atgaagggca
    36421 ttcagtagca attgaaggag aaataccagc agatttacaa gatttatgta aagaagccga
    36481 agaaggatgt ccagtttcag ctataacagt taaatagagc tgtttaaatt tatttttaaa
    36541 ataaatatat aagatttaat tgggtactta agctatagta ttagaaattt ctattactat
    36601 agctttttaa aatagataaa cttaatatgt aagatattac tttttacaaa tatggaggac
    36661 tgaaatatga aaaaaaatta tgaaatagta ttattcgatt tagatggaac acttacagac
    36721 cctaaagaag gaataacaaa gtctattcag tattctttaa atagctttgg cataaaagaa
    36781 gatttggaaa acttagacca atttatagga ccaccattac atgatacttt caaggagtat
    36841 tataaatttg aagataaaaa agctaaagaa gctgttgaaa agtatagaga atattttgct
    36901 gataaaggga tatttgaaaa taaaatttat gagaatatga aagagatatt agaaatgctc
    36961 tataaaaatg gtaaaatatt attagtagca acttctaagc caacagtttt tgcagaaact
    37021 atacttagat attttgatat agatagatat tttaaatata tagcaggtag caatcttgat
    37081 ggtacaagag tgaataaaaa tgaagttata caatatgtac tagacctatg taatgtaaaa
    37141 gataaagata aagttattat ggttggagat agaaagtatg acataattgg agctaaaaaa
    37201 ataggtatag attctattgg agtattgtat gggtatggtt cttttgaaga gcttagtgaa
    37261 agtgaaccta cttatattgt cgaaaatgta gagtctataa aagatatttt gttataaata
    37321 tcttttatag acaaaaatat tacaaaatgg tgtcgcatat ttaaaaatat gatattatag
    37381 ttaaggaagt catttaaaaa agaggaggat gcacttaaaa tgaaatctat tttaattatg
    37441 ggtggaagcg acttcatagg ttctgcactt gctaagcgct tgattaaatg tgggtatcaa
    37501 attgatatac ttacaaatgg taaaaaggaa atagattata atggttttaa agaacatcta
    37561 atttgtgata gaaaagttcg aaaagatatg gaaaacatta tcacaggaag aaaatatgat
    37621 tacatatatg atatgacagc atatacaaaa gaagatgtaa gtaatctgat tgattttata
    37681 agcatggata acttaaaaaa gtatatagta ttgtcagcag gagcagtata taaagatagt
    37741 ggaagaaata taaaagaaga aaatgagaaa ggtgaaaatg aaaactgggg aaaatatggg
    37801 ttaaataaaa aagaggctga agattttatt ataaatagcc ctataccata tataattatt
    37861 agaccaactt acatatatgg tgaaaataat aatttatata gagagtatta tttctttgaa
    37921 aaaatagaaa aaaatgaaaa gataccagta ccaaaaggaa aacaagttag taatcaattt
    37981 atatatattg gggatttggt aaaggtattg gaaagcataa tgaaaaatcc tcatgtaaga
    38041 gaggcctata atgtgacaaa tccacagtta atttcttggg atgaccttat atatacatgt
    38101 ggagaaatta ttggcaaaga acctataata aaatatgtag atatggaaaa agtagagttt
    38161 agagaaagaa cgtatttccc atttagaaat atagacttta atcttgatat aaataagctt
    38221 attgaacatg ggctttatat accaaatgtg ttactaaaag aaggtcttac agcaacatat
    38281 aaatggtttt cagcaaataa gccaaaaatg catgacagaa aaatgaacaa agttgagtct
    38341 gtaatgcaaa tagtttaaaa aaataaataa gtaggtagat attttgaact caaaaattaa
    38401 gtatttttta aaatttttta tcttaatatt tattttgatt tttatatact cagttgcgat
    38461 agagccgagt ctattaattg tgaaaaaata taatataagt gaaaatggag cattgataaa
    38521 aaatgataca attgagagta aatctgaaag tgtaaaagta gttcaaattt cagatactca
    38581 aataggtagt ttttattcaa ctaagaatct caaaaaagta gctaataaga ttaacacttt
    38641 gaatccagat ataatagtat ttactggtga tttaattgat tactccaata aaaatccaag
    38701 tgtagatgaa attacaacta ttttatcaag tatgaatgct aggttgggaa aattttcagt
    38761 atttggcaat catgattata tgtataaact tcctaggtat tataggcaga ttatgaaaaa
    38821 ttccaacttc aatcttttag taaatgaaaa taaaaaaata aaattaaaag atgataaata
    38881 tattaatata ttaggtgttg atgaaatatt aaatggaaat cctaatataa aatatctgga
    38941 gagtcagata gataataaaa attttaattt attgttagca catgaaccag atttagtaga
    39001 tatgcttagt aaagatacaa tgaatttagt tctatctggg catagtcatg gtggtcaaat
    39061 aagattacct attaagggag cattagttac tcctccatat gggaggaaat atactaaagg
    39121 gttttatgat ataaatggaa atcatttata tgtgagttcg ggtcttggaa gtacaaagtt
    39181 accatttaga ttttttaata taccagagat aatagaattt aatattataa tctaacataa
    39241 aatatttaga aaatataatt ttgcttttta taatatgtag atgtatatac tgtaaaaatg
    39301 gattaaacca gtagattgaa tgaattaata tattaaatta atatataaaa tatttaagtt
    39361 ataattaatg tattagacaa aataaatact attaagaact attaaaatat agattaaaga
    39421 taataacata taataaataa aaaagtaaga ttgtgtagat tatataaaga ttatttataa
    39481 ttaatacaat cttgcttttt tatttaaaaa ttttaattat tatttaaaat tttttatctt
    39541 ctctttatcc catataaaca atttctcaga attatttaaa gcgccaaata catttctttt
    39601 aaaatcaggc atctctttat ttaaattagc aataagattt tttatgtact ctctcctagt
    39661 atgaccattt gcagggcagg gatttgtgat aataggatag ttagaatctt ttgaaatttt
    39721 cttagtcata tactcttcta tgtaaatcat aggtcttata actgttaaat cctgtctatc
    39781 taggtatgtc tttggggaaa aacaatttac tctaccctca taaaacatag acattaaaaa
    39841 tgtctcaatt gcatcatctt tatgatgacc aagagctact ttattacatc caagtttttt
    39901 agcattatcg ttcaaagcac ctcttcttaa attagcacat aatgcacaag gatttttttc
    39961 ttgtcttata tcaaatacaa tttcttttat gtcagtttga aattcataaa aaggaacatt
    40021 tatttcttta cacaatttat ctagtggaga attatcaaca cctccagtat ttaatgttat
    40081 ggctatcaat tcaaagtttt gtggagaaaa tctttgataa cttttaagta tatgaagtag
    40141 agttaaacta tcttttccac cagaaagtcc aaccgcaatt ttatcatttt cttgtatcat
    40201 atcaaaatct tgtatagcct tacgagcttt acttagaagt ttttgtatag acattttatc
    40261 accatccttt aaaaatatta aatttaagat ttatttaaga tttacttata aaatacttaa
    40321 gtcttatact ctaaaattaa cattatagac aaacataaca aaaaggagaa gatttaatta
    40381 tgaaaaaatt taaattaata ggagccatta ttttagtagt atttataagt gtatttatat
    40441 ctaaagatag attacttaag aaagataaag atccaatagt agctgctcaa catgattcag
    40501 aacaagatgt tgaggcaaat tctcaaaata aaaatcactc aaatagtata tcaaatatat
    40561 tattggtaaa caagacaaat ggaattagca aaaactatac tcctgaaaat attactaagg
    40621 taaacatacc ttttgttgaa gaagcaacag aggaagaaaa acaaatggca ggagaacctg
    40681 caaaggcagt tgaagattta gttaagcaag ctaattcaga aggaatacag tttttagggt
    40741 cttcagcata cagatcttat gatactcaac tggatactta tacaagaagg gtaaaatctc
    40801 agggacgaga aaaggcagat gcatatgtag caaagcctgg ttacagtgag caccaaactg
    40861 gactttgtat tgatttaaca aatccagaaa gatggtttgt tggaagtaca aaagaagcta
    40921 aatggttggc agaaaatgct cacaagtttg gatttataat aagatatcct gaaggtaaag
    40981 aagatataac aggtacagca tatgaaccat ggcatattag atatgttggt aaggatgctg
    41041 ccgaggaaat ttattcaaaa ggattaactt tagaagaata tttacaaaat aaataatata
    41101 aatgtgtaaa taatttgtat tatattggaa atttagaaat gaataaattt atagattaca
    41161 ctaactaaaa tatagtataa ttttatatga ataaagctat atacaaagat taagttagga
    41221 tgtgtaaaaa tgaataatac agttcttgtt gtggatgatg aaaaggaaat aagagacctt
    41281 atagagatat atcttttaaa tagtggatat aatgtaatta aagctgaaga tggaaaagag
    41341 gctctagata ttttaaaaaa ggaaaatatt catttaatga tattggatat aatgatgcct
    41401 aaaatggatg ggatagaagt ttgtagaaaa gttagagaaa gtttgaatat accaatactt
    41461 atgttaagtg caaaatcaga agatatggat aaaatacaag ggataatgac tggtgcagat
    41521 gattatttga caaaaccatt taacccactt gaacttactg tgagagtgaa atcactgatt
    41581 agaagagcat attattttag tggtgctaat aatgaagata aagatgtcat aaaggttgga
    41641 gtagtaatta tagataagga aaaacatagt gtaacagtgg ctggaaatga aataattttg
    41701 acatcaagag aatttgatat attatattta ctagcaaata ataaaggcag agtatatagt
    41761 acagaagaaa tatttgaaaa ggtatggaaa gagaaatatt accaatctaa taatactgta
    41821 atggttcata tgagcagaat aagggataaa attgaaaaat atacagatgg agaaaaaata
    41881 attcatactg tatggggagt aggatataaa attgaaaaat aaaagtttat taaatcatat
    41941 gtttcgaccc atattagatc ttataataag ctgtgcttta acttcaatgc ttattttaac
    42001 aagtatgtat ataataaaat tattatattt caatagtgag atatctgtaa ttaatcaact
    42061 tgtatatcag ttaagagatt tcagaagtct tataggagag agtttatttt atccattttt
    42121 atttacaatc acatcattag caatttattc catgatatcg tacaagagaa ataagcaaat
    42181 tgtagatttt ataagaaaga ctaatagaaa aaatcaaaaa ttagaaatca ttaaaagtgc
    42241 tgtaaattta atggatgaag gtaacttaga aaaaagtata gatattgagt atgatttaga
    42301 tatattaaag gataaagaaa aggatgatat tgatgaacta gcacataaaa tcaataatat
    42361 agtccatcaa cttagaaata taactattga agagagacaa gctcagcaga caaaaacaga
    42421 tttaataaca aatgtgtcac atgacttaag aacacctttg acatccataa tgggttattt
    42481 aggagtgata gaagaaggta agtataaaga tgaagttcag atgatgtatt atgttgatat
    42541 tgcatatgaa aaatcgaaaa atttaaatgt tcttataaat gatttgttcg aattgactaa
    42601 aatgcaaaat aatacaataa aactaaacaa aatagaaata aatttagtag agttattaag
    42661 tcaagtagta tctcaatttg aaatttattt taaacaagaa tttatggtta gtagaattaa
    42721 ttttaatgaa gaaaaattaa ttgtgaaagc tgatccaaat aaattggtaa gagcatttga
    42781 aaatcttata actaatgctg tgaaatatgg aaaagatggg cattatgtag atatagtcac
    42841 agagaaaatg gaagatatgg cggttgtaaa agtgataaat tatggagaac caattccagt
    42901 gttagattta ccaaatatat ttgatagatt ttatagagtt gaaaaatcga gaaatagaaa
    42961 tgttggaggt tctggattgg gtcttgcgat tacaaaaaat attgtaaatt tacatgatgg
    43021 agaaattact gtttcaagcg ataaatatca aactgtgttt gaggtacaac tgccaataat
    43081 acaatcagct tagttataaa ataaaagtac gattatgtga tataaatatt ataacaataa
    43141 agtgtttaca aaaataaaaa agtgatatat aatttaagtc agtttaataa gatacttatc
    43201 aagaattagg ggagagagtt agctcagtga tcctatacca accttttatc aggtggtcct
    43261 gctaacaacg atgagatgac ttgaaataat atactcttct tatcaataat agataggaag
    43321 agtttttttt agaattaatg taacaaactt taaagtataa tggaggatta aataatggaa
    43381 aaagtagaaa gttttaagct agaccataca aaagtaaaag ctccttttgt aagaaagtgt
    43441 agtgtacttg atggagtaaa gggagataaa gtaactaaat ttgacttgag atttttacag
    43501 ccaaatgtag aaagttttgg aactgctgct atgcacggtt tagagcatct tttagctact
    43561 tatttaagag atacattaga tggtgtaata gacttatctc caatgggatg tagaacagga
    43621 ttttatttaa tactatgggg agatgtagat gccaaaacag ttaagattgg tttagaagaa
    43681 gcattaaaaa aagttcttga atcagataaa atgccagcag ctacagccat agaatgtgga
    43741 aactacagag acttatcttt atttggggca aaggaatatg caaaagatgt tttagataaa
    43801 ggattttctt taaatatata tggagaataa tttaattgga agagaagata taagcataaa
    43861 tcaaagtgaa gttttaagat atttacaata cagaggtcaa gagatagata aagaccttaa
    43921 atatactatt gatgaatgtg tagctataac taaaaataaa ataaatccta gatatttatc
    43981 taggatttat cctattagaa taaataaaga taatgttgta gaattagagg gaacaaattt
    44041 aacattagag agtaaagatg tatatgaact tttaaaagaa tgtaatgagt gtgtaattat
    44101 ggcagctact atagggatag atatagaaaa agaaataaga cgacactctt attcaaattt
    44161 aacaaaagga ctaataattg attcatgtgg aacaacagca atagaagaag tgtgtgacat
    44221 tgttcaaaat aatttagaaa aggttttttt aaaccaagat aaatttataa ctatgcgata
    44281 tagcccagga tatggagatt taccaataga aaaaaatata gatatattaa acgttttgaa
    44341 tgctcaaaaa caaataggtc taacaattac ttctaatgga attatgatac cgagaaagtc
    44401 agtagtggct attataggta tttctaatac aagaataaat aaatctaaga aagaaaagtc
    44461 gtgtgaaaat tgtaaaaact atagaaactg tacatataga aaaggagcga actcttgtgg
    44521 aaataagaca atatctgaaa aataatatat taatatttga tggtgcaatg ggaacaatgc
    44581 ttcaacaaaa agggttaaag ttaggtgaaa atccagaagt atttggtctt caaaatccag
    44641 ataaacttat agaaatacat acagcatact tagaggcagg ttcgaatgta attcttacaa
    44701 atacttttgg atgtaatgaa ctaaaattag atagtaagta tactgtagaa gaggtgattg
    44761 acaatgctgt tttggtggct agaaaagcta tagaaaatgt agataatact aaaccaagat
    44821 atgtagcttt agatattggt cctataggag aaatgctaga gcctatgggt actttaagtt
    44881 ttgataatgc atatgagata tttaaaagac aagtactaca aggcgttaaa tctggagttg
    44941 atgtaatagt aatagagact atgatggatt tatatgaagc taaagtagct gtattagcag
    45001 caaaagaaaa ctctgattta cctattttct gtactatgac atttgatgaa ggtggaagaa
    45061 gttttactgg atgtatgcca gaatgtatgg tggctactat agaaggtcta ggtgtagatg
    45121 caataggagt taattgttca ttaggaccta aacaactttt accaatagtt gaaaaaatag
    45181 catcaagagc tacagtccct gttatggttc aagcaaatgc aggtcttcca aatatagttg
    45241 atggagaggc tatatatgat gttgatgcaa aagaattttt tgaaggggtt aaaaagttcg
    45301 ttgaagttgg tgctactata ataggtggat gttgtggtac gaatccaagt tttataaaag
    45361 aaatatctga gaatataaat tctgttacaa agggatgtat cgagaaaatt gataaatgtg
    45421 tagtctgttc accatcaaaa tttgtggaag tacaatcgcc tacagttgtt ggagaaagat
    45481 tgaatcccac aggtagaaaa tctctacaag aagcattaaa aaatgaaaat gttgattatg
    45541 ctataaattt aggcttagaa caagtaaatg ctggagcaca aatacttgga gtaaatgttg
    45601 gtcttccaga gattgatgaa aaaaaactaa tgccaaaatt aataagagag attcaagcag
    45661 tagtagatac acctttacaa gttgattctt ccaatgtaga ggccttagag caaggactta
    45721 gatattataa tggtagaaca atagtaaact ctgtaaatgg caaagaggag tctttagaaa
    45781 gtatattacc aatagttaaa aagtatggtt catgtgtggt tggacttaca cttgatgaaa
    45841 aggggatacc taaaaaggct gaagaaagat ttgaaatagc aaaaaggata gtcaatagag
    45901 cagtttcttg tgggataaaa ccaaaagata tatttataga ctgtttatca ttaactgttt
    45961 cagcacaaca agaagaagca atagaaacta taaaagctat aacaatggta aagacactag
    46021 gagtaaaaac tatattaggt gtttcaaata tttcatttgg tcttccaaat aggaaagcac
    46081 ttaatgcttc ttttctaaca ttagctttag gggcagggct tgatttagca attataaatc
    46141 caaatgaata tagtatgatg gaagctatca attcttttaa aatattaaat aacacagata
    46201 aaggatgtat aaactatata aatcaatata gtaatataaa taattcaaaa aaatcggatt
    46261 catctacaaa gattgacaaa gatttgccat tggatatttt agttgaaaga ggattaaaag
    46321 atgaagcaaa aaatgtaaca ctgaatcttt taaaagagaa ggatgaaaat tacatattag
    46381 atgagatttt aattcctgct cttgataaag taggaaaaag atatgatagc ggagatatat
    46441 ttttaccaca attgattcaa tcagcagaaa cggtaaaagt ttcattaaat acaataaagg
    46501 aaactttatt aagtaaaagt agcaataatg tatccaaagg aaaaataata gttgctacag
    46561 taaaaggtga tatccatgat attgggaaaa atatagtaaa aataatgcta gaaaattatg
    46621 gatatgaggt tatagattta ggtaaagatg tccctattga agaagtagtg gaagttgcta
    46681 aaaagagaaa tataaaatta gtaggattaa gtgcacttat gactacgact gttcaaagta
    46741 tgaaagatac aattcaggca ctgagagata atgagataaa tgcaaaggta tttgtaggag
    46801 gtgcagtttt gacagaagaa tacgctgaag aaatgggcgc tgattattat tcaaaggatg
    46861 caaagtctgc tgttgaaata gcaaagttaa atttttagca tataaattaa aataaaggtt
    46921 ttactaaata ggatatttta tatataatat aaatataagt tttagatact tatgtttaaa
    46981 acaataggaa ttaatctata ataatgagat taattaatat aaaaaatatt tatcatcaac
    47041 attaaaaagg gctgggaagt ctggtataac ttccattagc cctttttagt taaaatcata
    47101 tgttaaaaag cccaattacc atttttaaaa atctgtattt gttttccatc ataagtctca
    47161 ccaataatat ccatatcagc agaaccaatc ataaaatcta catgtgttaa actgtcattt
    47221 acaccatgtt catctaattc ttcatctttt aaattgtttc caccttccag acaagtctta
    47281 taagcagaac caattgcaaa gtggcaagaa gcattttcat catatagagt attataaaaa
    47341 attatatccg tattggatat tggtgagttg tatggaacaa gagcaacttc tcctaaataa
    47401 tgagagcctt catccgtttc aataagtttt tctagtgtat ctaatccctt ttcagcagag
    47461 aaatctatta ttttaccatc tttaaatgtt aagaagaaat tgtcaattat gtttccacca
    47521 taaacaagag gttttgtact ataaacagtc ccatttactt taaacttatg tggcattcca
    47581 aaaatctctt cagttggaat attcggatta aaacttattc cattagggtc tttggatgct
    47641 ccacttagcc aaacatgacc ctttggcaag tctagagtca aatcagtttt tgaggattta
    47701 tattttaaag ttttaaagtt atttttattt agaaagtcca ttttagattt aagattttca
    47761 ttatgttctt cccatgcttt tatagggtcc tgaccatcta ctcttgaaca tttaaatata
    47821 gcatcccaca gtttttctat tgctttatct tctgataaat ttggaaacac tttttttgcc
    47881 caatcttttg ttggcacaga gactatactc catttacatt tatcagttag agtgtaagaa
    47941 cgccattctt ttaaagcttt tccagatgcc ttctgaaaat ttgcaactct ttcagggtca
    48001 acatctttta ataaatctgg attttgggca tagactgata aaaatgcccc accttctttt
    48061 gctatatcta catattgttc tgctgtccat ttggggaact catgaaatgc ttcatctgga
    48121 gcatacaagt atttaataag agtactttct tcatcagacc actctatata aacattttta
    48181 gcaccacatt tatatgcttc tttaagtgca tttcttgcaa aatcagcaca ttctattggt
    48241 gactttataa gtagaatttg acctggctgt atgttaactc caacttttat tgctaattca
    48301 gcgtattttt ctaaatttct atttaaattc atatttatcc tcctatattt ttaatattga
    48361 ataacttata aagtattata acattactta tgtttttaat attgaacaac ttataaaata
    48421 ttataacttt acttagattt tgggtcatat tcaaaatatt tatactttat agattgagaa
    48481 ataaaaaaaa tattttaatt aaaacagatt atgaggataa caaacttatt taagcagtat
    48541 gttttttgtt gataataata ttaaagtaga aataaaaata cttttttagt gaaaagctat
    48601 acaagaatac cgaaaaaaac ttataatata ataatgagat agatatttat aaatgaaaaa
    48661 aatttttctg gcaaagctta attaaaaagg taatagctag tgttgttatt taaattagca
    48721 tagaaaatca aataaaaaaa ttatgctaat gtatagacat tgataaggta gaatttaagc
    48781 cttttgaatg ctatattaaa ctagagtaga tattcttatg aatttcaaaa tagggcagga
    48841 ggaaaaagga aataaaacta taaaaaatat aaagtattta tataaattta tagagtttat
    48901 acgtcagaag atttcagtta ggagggcata aatggagctt tatgaagcca ttttttatag
    48961 aaaatctgta agaaattttt ccagtaagaa gataaaaaag ccattgatgg aagaaataaa
    49021 aagaagttgt aaaaatttag aatacttaaa tgaagattta aatattaaag cacatgttgt
    49081 tgatagaggt catataatac attttttgat gggtaaggaa tgtaaagtaa aggcacctca
    49141 ttatatagta gttacatcag acaaaggtga ggactattta cagaatatag gatttgctac
    49201 agaaggtgta gttttgcgcc ttacaacatt gggaatagct acttgctggt tggaaggaaa
    49261 cttaaagaga gaagatatct tggaatttgt agatattggg aataagaatt ttgaagaaga
    49321 tgaggaagat gatttagatt atctagctgg agtaaaaaca gaagaagatg atgaaaacaa
    49381 aatagaaaat ccttatataa taatagcatt tggatatcca gcaaaaaatg aagagttgtt
    49441 taggacgaga tatgctagac ctgatagaaa gccagtaaaa gatatgataa ataagataaa
    49501 taggaataga aagtggaaag atatcttaga attgacaaga agagctccat ctgtaaaaaa
    49561 ttctcaaccg tggtatttcc ataaggatga acgaggtctt catttatttg aaaagagacc
    49621 taagaaacac tgtgaagata tgaataaggt tagcttaggt gtagccttaa gacattttga
    49681 tatagcttgt ataaaaaata aaatagatgt ttcatatgaa aaacttccta taaggaataa
    49741 aataggaaaa tcatatttta taactgtagt cgagcatgtg aaaccagaag aagaaaccca
    49801 agaagaaaat gtaactctag aaaaagaaga atcacaagat gaataaaatt ttggaagggg
    49861 atattggata tgtataagtg tggaaaatgt aatcttagag gctgttctaa tggaaatatg
    49921 gataaattaa tgaagatatg tccaactaga gaaattgaac tacaacaaaa agcaaagcaa
    49981 ctttatgaag aagaagagaa tagaaaaata gcttataatg ctggattagt tgaagcagag
    50041 gggtattgtc aatatactag actaaaagag attatagagt ttgctaaaaa gtgtggttat
    50101 aaaaagattg gcatagcatt ttgtattgga ctaaaaagag aaatgcaaac agcacaaaaa
    50161 atatttgaac atcatgggtt tgaagtattt tctgttatat gtaaaaatgg ggcaatgcct
    50221 aagagtacaa ttggactaga agcatctcaa acaatatcaa agtgttcaga tgaggtaatg
    50281 tgcaatccaa taggacaagc tttattttta aatgaagcta aggttgacct taatgtaatt
    50341 cttggattat gtgttggtca cgatacttta gccatgaaat atatggaagc tcctataaca
    50401 actttagttg tcaaagatag agtaactggg cataatccag ttgctgcaat atataatgca
    50461 gaatcatatt ttgagaaaaa attgtttgat aaagatgaag aataattcaa agacttattg
    50521 acataaaaag caattagtgg tttaattata aaaaagataa aactttaaat tatcctatag
    50581 atacataaag ttatataaat aaagaaaaat attacagcta aattccttaa agtagtccag
    50641 agagactaaa gggttataga taatgttagt atataacctc tagtaaatct tctagaggtt
    50701 tttgatgagt ataaaataaa aatttaaata taataaagtc ttttaaacta gtccagagag
    50761 actgggaaag atatctcata gctaatgaat ggagttatgt atagataaaa tccttatgcc
    50821 tcttttggtg tgaggatttt tttatgatta tttaggcttt attaaaaagg agatgtaaaa
    50881 atgataaatg gtaaagaaaa attgatagtt gcaattgata ctgacgaatt tgataaagct
    50941 aaagaactaa tagacagatt agaagatagt gtagacatat ttaaggtagg tctagagcaa
    51001 tacgttgcca caaaaggtaa aacaatagat tatcttaaag aaaaagggaa aaaaatattt
    51061 ttagacctta aattccatga tataccaaat actatgaaaa gtgcagtgag agctgcagtg
    51121 agagataatg tttggttaat gacaatacat gtatcagata tggaaggaat gagacaatgt
    51181 gcactaattg ctagggaaga agcagaaaga ttaaatatag aaaagccatt agtagttgga
    51241 gtaacagttt taacttcatt aagtaaccaa gatttacagg acataggatg taatatgaca
    51301 acagaagagt tagctataaa gagagctaaa ctggcaaaag aatcaggcat agatggggtt
    51361 gtttgttcag cgcaagaagt agataaaata gtagaagcat gtggagctga ttttataaca
    51421 gtttgcccag gaataagacc taaatcagca gaggttggag accaaaaaag agttgtaact
    51481 ccatcagatg caataaaaaa aggtgctcat tatttagttg ttggaagacc tataacaaaa
    51541 gcagaaaatc caagagaatc agctattaat attgtaagag aaatagaaaa tgcttagata
    51601 aaatatttgg gaggtagctt atatgaaggg gaaattaatt ttagaagatg gaacagtatt
    51661 tgaaggaaaa gcatttggat atctaaagga agctattgga gaagttgtat ttaatacttc
    51721 aatggctggg tatggagaaa tattgacaga cgcaacttat tatggacaaa tagttactat
    51781 gacttatcca cttataggaa actatggaat aaatttagaa gatgttgaat caaataaggt
    51841 gcaagtaaaa ggacttattg taagagaaaa aagtgataac ccaaataatt ttagatgtga
    51901 aatggatata gacacatatc taaagcaaaa taaggtaata ggacttgaag gaatagatac
    51961 aagagcatta actaaaatta ttagaaacaa tggaactaag agaggaatta taactttaga
    52021 aaatgtatca ttacaagatg ttcagtctaa attagaagag cattgtaaca aagattcagt
    52081 aaaaaatgtt acaagaaaag aaattgaaaa tataaaaggt actggagcta aagttgtagt
    52141 tatagacttt ggtgttaaaa atagtgtact agagtctctt aaagcttgta actgtgatat
    52201 aactatagca ccagcaatga ctacagtaga agaaatttta aatataaatc ctgacttaat
    52261 cttattatct aatggaccag gaaatccaga ggatataaat gatatagttg aaaatataaa
    52321 aaaattaata ggcaaaaagc cattgacagg aataggttta ggacatcaaa ttttagcatt
    52381 ggcattagga ggaaagactt caaagcttgt atttggacat agaggaggta atcacccagt
    52441 taaatgttta gaaactggaa aggtatttat aacttctcaa aatcatggat ataatgtttc
    52501 agaaatgcca gaaaatacag aggtaactca cataaattta aatgacaata ctatagaagg
    52561 aatgagacat aaggaattac caatatatag tgttcagtac attccagaat acacaacaaa
    52621 agaagattta gattgtatat ttaataaatt cttagcatta atatagattt agtattattt
    52681 acagatagta aaaaccattt agataaggag aaaaatttat gcctaaatta gatagtataa
    52741 agaaaacttt agtattaggg tcaggaccaa taataatagg tcaagctgca gagtttgact
    52801 attcaggaac acaagcttgc cagtctttga aagaggaagg gattgaagtt gtattaataa
    52861 atagtaatcc agccactata atgactgata aagaagtggc agataaaata tatatagaac
    52921 cattaacaat agaatttata gaaaaaataa tagaaaaaga aagaccagac agtttacttg
    52981 caggtatggg tggacaaaca gggctaaacc tagcagttga actttatgaa aaaggcatac
    53041 tagataaata tggagtaaag ataataggta cttcagtaga atctatcaaa aaaggtgaag
    53101 atagagatat atttagagaa gtaatgaaag aaataaatca gcctgtaata gttagtgata
    53161 tagttacaga tttacaagca ggtcttgatt atgcacttac aattggttat ccagtagttg
    53221 taagaccagc atacacacta ggtggaactg gtggtggtat agctgataat gaggaagaat
    53281 taagagaaat actttcacat ggtctacaat taagtcctgt tggacaagta ttaattgaaa
    53341 agagtataaa aggttggaaa gaaatagaat atgaggtaat aagagattca aagggaaatt
    53401 gtatagttgt atgtaacatg gaaaatatag acccagtcgg agttcataca ggagacagta
    53461 tagttgttgc tccaactcaa actttaagta acaaagaatg tgcaatgctt aaaaaagcat
    53521 ctttagatat attaaatgca gtagaagttc aaggtggttg taacgttcaa tttgcactta
    53581 atccacatag ttttgaatat gcagttatag agataaatcc aagagttagt agatcatcag
    53641 ctttagcatc aaaagctaca ggatatccaa tagctaaagt ttcatcaaaa atagctttag
    53701 gttatacttt agatgagata gaaaatgcag taactaaaaa aacttatgct tgttttgaac
    53761 caactataga ttatgtggtg gcaaaaatac caaaatggcc ttttgataaa tttaaaaaag
    53821 caaatagaaa attaggaact aagatgatgg caactggtga aattatgagt ataggaagta
    53881 actttgaggc tgctattctt aaagggataa gatcacttga aacaggaaaa tattcattag
    53941 ttcacacacc atctgaggag agaagcattg aggaattaaa gaaaagagtt gtagtacctg
    54001 atgatgagag actatttgac ttagctgaaa tgataagaag aggctataaa gtagagatga
    54061 tagaacaaat tacaggtata gataaatggt ttataaataa atttaaatgg atagtagagc
    54121 aagaagaaaa attaaaagtt atgaaaattg aagatttaac taaagactat cttcttgaat
    54181 taaagaaaaa gggattctct gataaaggta tatctgactt aatgaagata agtccagaaa
    54241 aattatatga attgagaagt ctatacaata tcaaaccagc atataaaatg gttgatactt
    54301 gtgcaggtga gatagatgct atatctcctt actattattc aacttatgag caatatgatg
    54361 aggtagttgt tagtgataag aaaaaggtga tagtattagg ttctggtcca ataagaatag
    54421 gtcaaggtat agaatttgac tattgttcag ttcattgtgt aaaatcttta agaaaaatgg
    54481 acatagaaac tataatcata aacaataacc ctgaaactgt aagtacagac tttgatacat
    54541 cagataagct gtattttgaa ccattaacag aagaagaagt tttaagtata atagaaaaag
    54601 aaaagccaga aggtgtaata ctacagtttg gtgggcaaac agctataaaa ttggctaagt
    54661 ttttacatga aaaaaatata cctatactgg gaacagattt tgatgatata gatgcagcag
    54721 aagatagaga aaaatttgat gatttactag agagactaga tataaataga ccaaaaggaa
    54781 agggtgtatg gtcacttaac gaaggtattg aagttgctaa tgaattaggt tatccagtat
    54841 tagttagacc atcttatgta cttggtggtc aaggtatgga aataacttat aacgaagaaa
    54901 aattatctca atatctaca
//
LOCUS       DAMJYN010000015        54577 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.015, whole genome shotgun sequence.
ACCESSION   DAMJYN010000015 DAMJYN010000000
VERSION     DAMJYN010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 54577)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54577)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54577
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.015"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(355..3462)
                     /locus_tag="PC466_001030"
     CDS             complement(355..3462)
                     /locus_tag="PC466_001030"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HDF2768425.1"
                     /translation="MAKFKPLVDSSVKQAEAQVFDYWKDINILEKTLEKGKDDPSFVF
                     YEGPPTANGNPGVHHVLSRTLKDSVCRYKTMSGYQVKRKAGWDTHGLPVEIQVEKELG
                     LTSKQQIEEYGIAEFNQKCRESVFSFEKQWRIMTERMAYEVDLDNPYITLDNNYIESV
                     WWILNKFNKEGYIYEGHKILPYCPRCGTGLASHEVAQGYKEVKTNTVIAKFKKKDADE
                     YFLAWTTTPWTLPSNVSLTVNADVDYLKVKKGDEVYYVSKPLADKVLGEDYEVLEEMK
                     GKDLEGLEYEQLMPFVEVDKKAFFITVGDYVTTEDGTGIVHTAPAFGEDDYNTGKRYD
                     LPVIQPVDETGKFTSTPWEGRFVMEDGLDVEIIKWLASENKLYSKEKVVHNYPHCWRC
                     QTPLVYYAKPSWYIEMTKLKDKLIENNNGVKWFPSFVGEKRFGNWLENLNDWAISRTR
                     YWGTPLPIWRCECGHTDSVGSRAELAEKAIEDVNPETVELHRPYVDDIHLKCEKCGKP
                     MTRVTEVIDCWFDSGAMPFAQHHYPFENKENFDQLFPADYISEGIDQTRGWFYSLLAV
                     STFVLGKAPYKSVLVPDLVLDKDGKKMSKSRGNTVNPMELFDQYGADALRWYLLYVSP
                     PWTPTKFDMDGLKEIQSKFIGTMKNVYNFFTLYANTDDINPTEFFVEYKDRPELDRWI
                     LSKFNNLMKDVEENLAIFELNKTLRMIQDFINDDLSNWYIRRSRRRFWATELTEDKKA
                     VYNTTYELLHGLCRAIAPFAPYMSEEMYRNLTGEVSVHLAEYPKCNEELVDTKLEEKM
                     DLAKNLVTLGRASREVERIKVRQPLQKVLVDGKFEDTISDVVDLIKEELNVKEVIFAK
                     DLDEYMNFSLKPNFKEAGPLLGSKMNLFVGALSKLNAHETANKLEKGETLTVDLDGEA
                     FEFNKDLVLIGITAKEGFNVSVENNLFVILDTKLTEELINEGYAREFISKVQQLRKSN
                     NFEVLDNIVIEYCGDDEIAKAVDHFNEYIKSETLALEINRVDDKSLEEQNLNDHMTGI
                     KVIKK"
     misc_binding    complement(3555..3787)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(3962..4489)
                     /locus_tag="PC466_001031"
     CDS             complement(3962..4489)
                     /locus_tag="PC466_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HDF2768426.1"
                     /translation="MLTPIEIENKEFKKGLRGYRDEEVDEFLDIIKEDYESLCRENTA
                     LKEKLGLYQDQVNKYENIEETLKATLITAQSAAEDTCSAANKKAKIIVEEADLKARQI
                     IEQANNRVIEIRKEYDALVKEFKIFRNKFKSLLEDEIRSVDEIFYDVDEKCVNAFEGT
                     TVYNYSNDEAATTLE"
     gene            complement(4524..5309)
                     /locus_tag="PC466_001032"
     CDS             complement(4524..5309)
                     /locus_tag="PC466_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HDF2768427.1"
                     /translation="MDKLKLTNHIKDIDLKNKMFKVIDKANSCIKNYDVKSTEFLNPY
                     EVKNAVAILNSTNEIKYSVDGGYEQAERSTVFIYPFYMEYEDIEDTLRFLQIEGNFKF
                     KNISHKDYLGSILGLGIKREKIGDIIIHDSFCQVVVSSDICDFIIVNLEKVSRNNVIV
                     KEISRENIVNSSSKYKEVSFTVSSDRLDCVISGIYNISRQDSAKYINGEKVHVNYEKI
                     TSTSKIVKNDDLISIRGKGRAKVTQIGDITKKGKIKVQARLIV"
     gene            complement(5319..5576)
                     /locus_tag="PC466_001033"
     CDS             complement(5319..5576)
                     /locus_tag="PC466_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HDF2768428.1"
                     /translation="MGTIRIALYYLLDIIAWMIVIKSLMTWFPNGRQSKIFNILENLT
                     EPIEGPIRSIMYKYTNGPIDFSPLIAIVLLMFLRQLVLVIF"
     gene            complement(5595..6053)
                     /locus_tag="PC466_001034"
     CDS             complement(5595..6053)
                     /locus_tag="PC466_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HDF2768429.1"
                     /translation="MSNGIISKFKNWIVDEEEDYIEDEYESGMDDIVQEEEMNSGFST
                     AKANKIVNLHTTSQMKVVIVEPKVYDEAATIADHLKQRRAVIVNLEGLTNSEVRKSIF
                     NFMNGAVYVLDGSIQKVSKSIFILAPNNVDIDANMKKELESKAFFPWQNK"
     gene            complement(6093..6797)
                     /locus_tag="PC466_001035"
     CDS             complement(6093..6797)
                     /locus_tag="PC466_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HDF2768430.1"
                     /translation="MGSIKDNLSEIRNKIDKAAKKVDRDSKEITLLAVTKTVDVDLVN
                     EAMREGITSVGENKPQELARKYDIIGDKLNWHLIGTLQTNKVKYIIDKVCMIHSLDRI
                     ALCEEIQKRAEQINREIDCLVQVNISKEESKHGLDREEVVDFVKEVSEKYKNIKIKGL
                     MTMAPFIEDEDEIRGVFKGLKDLSKQIKELNIPNVGMDVLSMGMSHDYEIAIEEGATI
                     VRVGTSIFGERNYNKK"
     gene            complement(6807..7442)
                     /locus_tag="PC466_001036"
     CDS             complement(6807..7442)
                     /locus_tag="PC466_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768431.1"
                     /translation="MKKVKYTRLVILGILIYLVFNILVMIISKNVDTLVLKNEKVDAK
                     IPVKGTIEKDANDQSNYLSTYISKEDSNNFEKNQNVIIEYHEQKLDAKVYKIYENNNK
                     IMVKLKISNQIVANQDTSVEEFDIIYNQMECLKIPKTSIKTKDNKRGVYVIDEQSQSV
                     KFVILEGITYENESSVFVDYYKNDINGVTSVNLYDKIILRPNSINTNIRIK"
     gene            7823..8863
                     /locus_tag="PC466_001037"
     CDS             7823..8863
                     /locus_tag="PC466_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF2768432.1"
                     /translation="MSEILLGTGLLLLVLCCFTIFSYKAPYGMKAMGALANAACATFL
                     VEAFNLSLLGDVLGMEFFRSVGAANGSLGGVAAAILVPLALGVSPVYAVLIGLSCLDF
                     SILSGFVAGYFVSFLIKFIEKKVPPGVDLVVVILLCAPLSRLIASNVDPLVNSTLLQI
                     GQVLIEATNISPIIMGIILGGIITVVGTSPLSSMALTSIIGLTGLPMAIGALGAFGSA
                     FMNSTLFAKLKLGSKKDIISVAIEPLTQSDIISANPIPIYSTNFFGGAFSGIIVALMG
                     LVNMTPGTATPVAGFAIMFAYNPVQQVLITAGLCALFNVIAGFLGSKIFSTFKVLTAG
                     EIRGTDVEEEIA"
     gene            complement(9326..10681)
                     /locus_tag="PC466_001038"
     CDS             complement(9326..10681)
                     /locus_tag="PC466_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009170073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HDF2768433.1"
                     /translation="MNVGNILETIKMIDEEQLDIRTITMGISLLDCIDPDGDKAREKI
                     YNKIMSSAKDLVKVGKDIEREFGIPIVNKRVSVTPISIIAGATDENDYVKFAQTLDKA
                     AEDLGIDFIGGFSALVQKGYTKGDKILIKSIPKALASTNKVCASVNVGSTRCGINMDA
                     VKEMGEIIKETAELTKDAKGFGCAKLVVFCNAVEDNPFMAGAFHGVGEADRIINVGVS
                     GPGVVKRALEKVKGEPFDVVSETVKKTAFKITRVGQLVAKEASSRLDVPFGIIDLSLA
                     PTPAIGDSVANILEEMGLEVVGTHGTTAALALLNDAVKKGGVMACSHVGGLSGAFIPV
                     SEDAGMIDAVIKGALSIDKLEAMTAICSVGLDMIAVPGNTTAGTLGAMIADEAAIGMI
                     NNKTTAVRIIPAPGCDVGDMVEFGGLLGRAPVMPISTNSSELFTQRGGRIPAPIHSFK
                     N"
     gene            complement(10707..10976)
                     /locus_tag="PC466_001039"
     CDS             complement(10707..10976)
                     /locus_tag="PC466_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010963800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HDF2768434.1"
                     /translation="MKAILTVIGKDKPGIVAGISDELYKQNINIVDISQKILQDYFTM
                     IMIVDLEKSLNSFEKTVEDLVERGKKLSVDVKIQREEIFNSMHNL"
     gene            complement(11266..13206)
                     /locus_tag="PC466_001040"
     CDS             complement(11266..13206)
                     /locus_tag="PC466_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768435.1"
                     /translation="MKKYEIFIFMSIIVLCFISFPHKVFGQEENCLEDFERWVQENKN
                     NKEEIVYTLSCNMVIDEEFRFYIPYDSNFTIDTNKYKILIKNHGRFIIDDNELNIIGE
                     GGKEGVIHIENGGSISIGINNIIATDGTALYVEEGGDLHIKSSYESVEKIKANGKDAI
                     GIYTENDIRILNKDIEVNGEHAIGVYSKGDVEIEETSIKAYSSNNESGLLRDNNKLAQ
                     SIISESKKVYIIDDYNELIPSIAKDSGYNIVKCCHRGIGVFSDEIKVSKDDKIENIKF
                     PKYMVLETSSGNQLDIDVEWDFTDYYEKLEKGENFDITGKFKTEMLNKEKIIINDDVV
                     PILNVSVIEKKTIDNLELEFQNTKNGYVAVLFYDMPYSASKVFVEYSSDGINWISEEQ
                     EDIRDQAILFFEDFKLRCFRVKVVGGLKEGYSNIVFKPGFIMGGGDNQETPDDEREND
                     DIDGDRGGGGRDDPDRDEDDNNQDGNNGNENNDSNNNQNNNNENNNSDEKQPNTPKDD
                     VESSTDSNENKNPHDIPKDGNKENNSDKEKGFYNKNPITENDDNYDLSSKSVFGTNEH
                     SFPYRESISNKNQDTNKNKSNISDYDGIINNNYKLESKEYNLKKDIIFLFCILTPIMI
                     GSILIVNPDTRKSIIKFIKLKK"
     gene            complement(13390..14865)
                     /gene="spoIVA"
                     /locus_tag="PC466_001041"
     CDS             complement(13390..14865)
                     /gene="spoIVA"
                     /locus_tag="PC466_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage IV sporulation protein A"
                     /protein_id="HDF2768436.1"
                     /translation="MNNNIYEDISKRTQGDIYIGVVGPVRTGKSTFIRKFMEKLVIPN
                     IDNEFKKDRTRDEIPQSGSGKTIMTVEPKFVPADGVEIKIKDTVSLKVRMVDCVGYIV
                     EGALGHEEGGKQRLVSTPWSQEAMTFEKAAEIGTKKVIKDHSTIGIVVLTDGSVTGID
                     RKSYVEPEERVIQELKNLKKPFAVVLNTLSPKSEETSMLRSELEEKYEVPVLPMNVVE
                     MEEEDIEEVMEAVLYDFPLTEIRINLPKWVEGLERNHWIKSSIITTLKQSIIDIGKIR
                     DIEGIIQGFSELEFLEDTGVDNVELGEGVINIDLQTKQDLFYNVLEEKSGFKIEGDYQ
                     LLSLITRLSKVKNEYDKIESALIDAKIKGYGVVAPSLEELSLEEPEIMKQGKQYGIKL
                     KANAPSLHIIKADISTEVSPIVGNQNQGEEMIKYLMEVFEEQPADLWESNMFGKSLHD
                     LVKEQLQSKLYTMPEEIRVKMQKTLQKIVNEGSSNIITILL"
     gene            complement(15037..16332)
                     /locus_tag="PC466_001042"
     CDS             complement(15037..16332)
                     /locus_tag="PC466_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2768437.1"
                     /translation="MSVEVNKPSIWKNFKVLIILFVAGAFIYALPYLKNYYYDTFAQA
                     FNLTNTQMGSLGSIYGLLAMVSYLFGGFLADRISARKLLSGSLIITGISGLVLTLYPP
                     YIVVFLIHALWGITTILTFWPALVKAVRMLASENEQGKAFGFMESGRGITNAIHLSLV
                     LILFGYISSKVSDKSGLTAIIVLYSAINVIVGVLVFFKLKDNEKEVSAKFDKEAFFAV
                     IKMPHTWIITIIMFCSYSANMSFYYFTPYSTEAFGATVVFASAISILAQYCRPVASAA
                     SGLLGDKVGSSKIISYGFILMIAGLLGVIFTPTKSSMIYILLIGCVAIYVSMYAIQGL
                     HYSLLEEGNYSLSISGTAIGIVATLGYLPEVLCPLAAGKILDAFPGVTGYRYYFIVLT
                     IVAIIGLVFTFIWMNMTKERRKELIEMNNKSNENTTKVS"
     gene            complement(16516..17925)
                     /locus_tag="PC466_001043"
     CDS             complement(16516..17925)
                     /locus_tag="PC466_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDF2768438.1"
                     /translation="MKKKIGFWDLVFMNISALFGIRWIAKSTASSFGLGLGSIPVWLL
                     FAFIFFVPASLICAELAATYPKDGGLGEWVKQAYGEKWGFMVSWLNWTSKIFWYSSFL
                     TFLAINIAYMLGNPDLSNNKMFILALSLIIFWLLSLVSTRGMAFGKFFTNTGALGSTI
                     PAILLIVMAFMSVVILKKAPSASIYTIQNIIPKIDANSLVSISAIIFALSGAETTANF
                     ITEMDNAKKNFPKAILTVAVLIGGIYILGSVAITMILPPDKIAASTGILDALAKVAQD
                     LGIGSWFIRIVAFGITLSVLGALILYIAGPVKMLFGNVREGVFPKQLTVTNKYNIPSN
                     AVIVQAIIVSLLLVGTNLLPSVDNIYNVLVTMTALTALFPYVLLFTSYIRLRKTRPNE
                     ERPYSIAKSDSVCINIARMVLVVTVVGILFSTAPVMETLKDNIIYEIEMIGGGLFVII
                     TGLMLWKNYEKKISNNSGR"
     gene            complement(17977..19116)
                     /locus_tag="PC466_001044"
     CDS             complement(17977..19116)
                     /locus_tag="PC466_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HDF2768439.1"
                     /translation="MSNNMRLERLRKYMNEKSIEIALIFEPDNQFYISGFKAITYSRP
                     IVTVVTQDKIELIVPGLEELHAKEVAKVDNVYVYYEIPEMKEHGISHKHYLDIILNKY
                     PKGTTVGIEKDIVSASFSEYITDKSFAIKDVGSKIFEMRYVKDAKEIEFLKIAGYLSD
                     IGIKGSLENVRVGMSELEFDVAGDNALLKYVSENYPDTYIGFANWTCSGIDRTAQPHL
                     DSNTRILQRGDIVIHSRQVWYENYRAENERTFIIGKPTERQKEVFKIAVEAQQAGLDT
                     IKAGIPARMVDEAARAVVAKYGLELYSNHRIGHGLGLSEHEEPYLRFDNELILEEGMV
                     FSMEPGIYIPGVGGFRHSDTAIVGKNGATIITNYPRSVEELILDI"
     gene            19435..20085
                     /locus_tag="PC466_001045"
     CDS             19435..20085
                     /locus_tag="PC466_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2768440.1"
                     /translation="MTNKELQKKRILMYFIEAAQNIMENEGIENITLRKVADMAGYNS
                     STLYKYFKNLDHLISFASIKYFKDYNLNISRCIENVNDEYKKYIIMWKLFCKHSFDNA
                     QAFYQVFFNLSSDELSYITKQYYDMFPEDLGIHDSDISLMITGESIKERNKILLNNLV
                     DTGYIPAKDLDIINDIIISFYQNLLFLKKNTGKNSGDDELTMKMISSIEYIIKHAK"
     gene            complement(20242..21261)
                     /locus_tag="PC466_001046"
     CDS             complement(20242..21261)
                     /locus_tag="PC466_001046"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HDF2768441.1"
                     /translation="MEKVCVLGTGSWGSALALGLAKKGNDVSMWTRKEEQAKKINRTK
                     ENTDYLPGVLFPNNITISTDIEKTIKDCKVIVLAVPSQAVRSTCQKIKPFIKEGQVIV
                     NVAKGLEKGTGLRLSQVCEEELPQNPYVILSGPSHAEEVARDIPTTVVVASKDLKIAQ
                     MIQDLFMSPKLRVYTNPDIVGVELGGALKNIIAFGAGICDGLGYGDNAKAALMTRGIS
                     EMSRLGIAMGANMSTFAGLSGIGDLIVTCTSMHSRNRRAGILIGKGMSLEDTLKEVKM
                     VVEGITATEVAHDVAEKLDIDMPITNAIYSVINKGSNPKEVGIELMMRSKKHEMEEVV
                     LGDDI"
     gene            complement(21292..21906)
                     /gene="plsY"
                     /locus_tag="PC466_001047"
     CDS             complement(21292..21906)
                     /gene="plsY"
                     /locus_tag="PC466_001047"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HDF2768442.1"
                     /translation="MEIFSYIIIAVVAYLLGNISTSYIVAKRIAGVDIRTQGSGNAGS
                     TNVLRTLGKRAGAMTFLGDVLKGVMAVLISEFAARLVGIDTLLAGYLAVICVVAGHNW
                     PAVLGFRGGKGVATSLGAMLAVNPVITLMCLAVFILVVAITKYVSLGSVVGIGCSPIF
                     MIMVKNKAGLIVALFLTASVIYNHRANIKRLLNGTERKIGQKKE"
     gene            complement(21941..23260)
                     /gene="der"
                     /locus_tag="PC466_001048"
     CDS             complement(21941..23260)
                     /gene="der"
                     /locus_tag="PC466_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012063975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HDF2768443.1"
                     /translation="MSRPVVAVVGRPNVGKSTIFNKFAGKRISIVENTPGVTRDRIFA
                     EVEWLDKYFTLVDTGGIEPDSEDIILSQMRNQAMLAMDMSHVILFIVDGKAGITAADK
                     EIAQLLRKTKKPVILVVNKIDSQSQFDNIYDFYELGFGTPFAVSGANSMGFGDLLDEI
                     VENFPAGLDTEYEEDIIRVAITGKPNAGKSSILNKILGEERVIVSPIAGTTRDAIDTY
                     FEKNGQKFLLIDTAGLRRKSKIYETIEKYSVIRAMSAVDRADVVLIVIDALEGVTEQD
                     TKVAGIAHDEGKGCIFVINKWDLIEKDNKTMSNYTKDIKEKFPFMMYAPIVFVSAKTN
                     QRMNKILDTVEYVSNEHSKRISTSALNEVIGEAVMLNQPPSDKGRRLKIYYGTQTDIR
                     PPKITLFINDKDLTHFSYQRYLENKIRENFGFEGTSIKFEYRQKNKK"
     gene            complement(23294..24622)
                     /locus_tag="PC466_001049"
     CDS             complement(23294..24622)
                     /locus_tag="PC466_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF512 domain-containing protein"
                     /protein_id="HDF2768444.1"
                     /translation="MEVNVKKVNNIISKVYKDSIAEEIGIEVGDLLISVNEQPIHDII
                     EYRFLLSDEYLDVEIQKKDGEVYIYEIEKDYDEDLGVEFTNPIIDQAKSCRNKCMFCF
                     IDQLPEGMRETLYFKDDDSRLSFLQGNFVTLTNMSEEDINNIIKYRISPINISVHTTN
                     PELRQKMISNKFAGKLYGIMKRLADAHIEMNCQIVLCPGINDGKELDRTIKELAQLYP
                     YVNSVAIVPVGITKHRENLVELNIFNDKSASKTIEQIHQIQQKYLEKLGTRFAFLSDE
                     FYILSNSELPGYEEYEGFLQFEDGVGMIRKLKTEIEEYLNILPENILKREKKVSIATG
                     HSAYEFIQSMADAMMDKFKNLQVNVYEIKNKFFGETITVSGLLTAKDLKEQLEDKELG
                     EALYITRSMLKADEEIFLDNIELNQLEELMRIKIIPCLNEGKDFVDKILK"
     gene            complement(24860..25060)
                     /locus_tag="PC466_001050"
     CDS             complement(24860..25060)
                     /locus_tag="PC466_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768445.1"
                     /translation="MGMDIGLNEYTLAIVTLDKNMKNGGGCPIFYANDEKDLQNKALL
                     MSKCVGGMVHDMTNGTLIIVKH"
     gene            complement(25062..25994)
                     /locus_tag="PC466_001051"
     CDS             complement(25062..25994)
                     /locus_tag="PC466_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YIEGIA family protein"
                     /protein_id="HDF2768446.1"
                     /translation="MDRVFFVAVIIGITSRIIMLNLDQKQYPTQPNVLLSQLILAFVA
                     SSLGALLVPALINRSYTSITFLSLAAEQFRQVRANRRNTLQNLEEVQLVKRGAAFIEE
                     IARTYEVRNYMCIVTSFLTIGLYYVILAETKISEGMSLVISSICGLVLAFILKKLLTR
                     KSIGDIADVMPAEISFVDESILKVGDLKGITNIGLKSDREVYINRGVGIQIIPKNKDY
                     ANAGILFDSGQRQAIVYNIYSRLGLYGDYGEPSFVPLPRRNKEDESIMIAYLPVDKNM
                     EKVMEAVKSCPILSSSKGKNLSLKNYKIGKKGSA"
     gene            complement(26039..26971)
                     /locus_tag="PC466_001052"
     CDS             complement(26039..26971)
                     /locus_tag="PC466_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YIEGIA family protein"
                     /protein_id="HDF2768447.1"
                     /translation="MEESLLNANLFRHSFIVALVVGILCRGLVLRVTDKQYPSRPQDY
                     LEQIIISGLSASLGAIALPALIDKEFAALTFFAVAIQQFQGLAEQERITLKNIDNEEL
                     VPKGDAYVEEIASTYESRSYISLFSALVSSIVYIVFARKYDLSFFHCTILAIVSGAIV
                     GLIFRRFLRRNSIADIADIVPAKISFEGPILMVNDVIITNIGLESTREKYRNECLAIE
                     VIPRDLGAFGIVNDIGQRQAIIHNLFIHMGIDRDVDEVDIVAISKTNLEKSTVVIPYM
                     PILKDIDVMIDVVKSTPIIETSKGKQSDFSRKTL"
     gene            complement(27026..28315)
                     /locus_tag="PC466_001053"
     CDS             complement(27026..28315)
                     /locus_tag="PC466_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF2768448.1"
                     /translation="MEDLNSIYFFIVMLSIAIVILAVRYTITLRKYLKEFIYVSKKVS
                     NNEYHARLNISAKGELGELARNFNHMIKNMDKTLEEVQYKHLQLRSILKSISHGILAI
                     DVNGNILLINDEAKEMIKSEPNQLVEGHNINVVIKEEEILKQILQFIGSKDNETANIT
                     TKDDIVYKIKVDPVYLQNTNNVIIGSIVNIEDITKKVKLENMRSDFVANVSHELKTPL
                     TSISGFVETLKSNENIDVNTRNRFLEIIESESDRLKRLIDDILLLSFVENKDTLLMEN
                     VVVYDVFKEVYEITQHSASEKNIEVLYKCDDKSISILSNKDYIKQVFLNLVDNAIKYT
                     QDNGIVQVVVLKDEEKIVIKVIDNGVGIPKEDVERIFERFYRVDKARSRDVGGTGLGL
                     AITKHIVKSLNGCIKVKSELGIGSEFIVTILQKNFLK"
     gene            complement(28344..29036)
                     /locus_tag="PC466_001054"
     CDS             complement(28344..29036)
                     /locus_tag="PC466_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2768449.1"
                     /translation="MNTKVLVIDDEMHIVELLKFNLEVSNYEVSYSYDGFDGFIKAKE
                     IKPDLILLDWMLPNISGIEVLRKIRSDKDLKNIPVIMLTAKNMENDKVEGLEIGADDY
                     ITKPFSIKELLARISSVLRRYNLTSLGEENNILTTGNLKLDLSKHEVTKGSEKIELTL
                     KEFELLKLLIQNKGKVLSRNYLLDKIWGYEYYGETRTVDVHIRYLRKKIEDEDKSEKY
                     IETIRGVGYKID"
     gene            complement(29051..29812)
                     /gene="pgeF"
                     /locus_tag="PC466_001055"
     CDS             complement(29051..29812)
                     /gene="pgeF"
                     /locus_tag="PC466_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan editing factor PgeF"
                     /protein_id="HDF2768450.1"
                     /translation="MMKDYINIKNVQDIKEYVNLSGNCEELDEKLNSVNLVITCKNID
                     AKNREDMLKVCKECDLTFENITSNSQIHSDIVNIVNKDTIGKRRDGDALITNLEKVPL
                     LLFTADCVPISIIDAKNKAIGLAHAGWRGTFSNIGHKTIKLMSECYKTVPEDLVCIIG
                     PSIGPCCYEVSEDLVEKFNTILTNNDEKFYIIKEGSYYLDLWKINEYMLRCSGVKKEN
                     IINLNLCTSCRADKFHSYRKHNKASERIGTVLQIK"
     gene            complement(29809..30270)
                     /gene="nrdR"
                     /locus_tag="PC466_001056"
     CDS             complement(29809..30270)
                     /gene="nrdR"
                     /locus_tag="PC466_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HDF2768451.1"
                     /translation="MQCPYCNYKESKVIDSRHTDLKSIRRRRECESCKKRFTTYEKIE
                     TTPLMVIKKDNSREYFDREKIKYGLLKACEKRPVSIEEIESIVVHIENEINKCFIEEI
                     ETKKIGEMVMDKLKELDEVAYVRFASVYRQFKDINTFVNELKSILIEKGDK"
     gene            complement(30292..30555)
                     /locus_tag="PC466_001057"
     CDS             complement(30292..30555)
                     /locus_tag="PC466_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlmC/YmxH family sporulation protein"
                     /protein_id="HDF2768452.1"
                     /translation="MIRVSDIMEKEIINVKNGKRMGFIIDIDMDIHEGKVVSFTIFGD
                     GSRSFFSRGGDEEVIFWNDILKIGCDTIIVNIGSELSLDEFEI"
     gene            complement(30659..31432)
                     /gene="sigG"
                     /locus_tag="PC466_001058"
     CDS             complement(30659..31432)
                     /gene="sigG"
                     /locus_tag="PC466_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigG"
                     /protein_id="HDF2768453.1"
                     /translation="MQVNKVEICGVNTSELPVLKNKQMKELLLQIKNGDEEARQQFVR
                     GNLRLVLSVIKKFNNRGENIDDLFQIGCIGLIKAIDNFDLSQNVRFSTYAVPMIIGEI
                     RRYLRDNNPIRVSRSLKDIAYKALQVRERLIRTNSKEPTVSEIAKELELEVESVVMAL
                     DAIQDPISLFDPVYQDNGDAIFVMDQVQDKKDTDENWLQEISLKEAIKKLNSREKLVL
                     DLRFYKGRTQIEVADEIGISQAQVSRIEKNALKNMRKYV"
     gene            complement(31524..32246)
                     /gene="sigE"
                     /locus_tag="PC466_001059"
     CDS             complement(31524..32246)
                     /gene="sigE"
                     /locus_tag="PC466_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigE"
                     /protein_id="HDF2768454.1"
                     /translation="MLRLKERIISFITMLGIKLKIIKPKGIYYMGGANILPPPLKPEE
                     EMELLQKLETDESVKSILIERNLRLVVYISRKFENTGIDVEDLISIGTIGLIKAVNTF
                     KLNKNIKLATYASRCIENEILMYLRKNNKKKTEVSFDEPLNIDLDGNELLLSDVLGTE
                     NDEIYKIIEEEIDRDLLVMALDRLSDREKQIMELRFGLIDKGIEKTQKEVAGMLGISQ
                     SYISRLEKKIISRLQKEMKKFV"
     gene            complement(32271..33143)
                     /locus_tag="PC466_001060"
     CDS             complement(32271..33143)
                     /locus_tag="PC466_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-E processing peptidase SpoIIGA"
                     /protein_id="HDF2768455.1"
                     /translation="MFKGFKGGYMVYIEYYVIENLVINYIIISCTSILTKRYNPKKNK
                     LLGASLGSAYSVAYLYPSMNILFTVPFKIIIMSIITLISFRSKSKKDYVHVALVFYLV
                     NIFISGSTYFIIYFTGISHLKISFLIACTYVSCELLKYIYKDLKMLKYIKELTKTINI
                     NLLEKSFCCKALVDSGNLLKDPISQSDVIIVKSSVLEGFIPEKLLNINYEDIDMKKAQ
                     EIIGSLDDKTSGRVRIIPYKHAGSNKTSIIIGLKADYIEVDEQKIGNIILGISNFNDR
                     EYGAIMNPNILPGF"
     gene            complement(33434..34708)
                     /locus_tag="PC466_001061"
     CDS             complement(33434..34708)
                     /locus_tag="PC466_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HDF2768456.1"
                     /translation="MIKLKKVLSLVMVGILSVSILAGCSKKEDSKGKEGKEKLVVWSA
                     PLTDHDADAWKPIFEKFEKENNCEIEFQIVPWDNYAEKYATAISAGEGPDIGYMYAEM
                     FPQFIEMGAVEDLTPYLEKSGTSDNYLYLDDAKMMGGIYGLPIEAANPGVLYYNKDIL
                     EKLGEKPPKTWDDFKRICEKATKDTDGDGKIDQWGLAQGWGSKVFGSLNWNWYPYLWQ
                     AGGDIYNDDLKSVKFNNAEGLKAANFINDMKKYIPEDALSKDSNEMIESVFGPGKAAF
                     TIMLSSAATSTFDKSFPDLNWGYVTSLEDKTVGSFASVDDLTLMSACKNKELGFKLLE
                     YMLSKESMEAFHKEIPRAPVAKGEKYQGDPRFEEMVTRDKHMYRPLTVGPHGVEIYEY
                     LWKQLQMMIAGDITPEQALNESAKYANGLLAQ"
     gene            complement(34992..36149)
                     /gene="ftsZ"
                     /locus_tag="PC466_001062"
     CDS             complement(34992..36149)
                     /gene="ftsZ"
                     /locus_tag="PC466_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HDF2768457.1"
                     /translation="MLNFDVELEECAQIKVIGVGGGGNNAVNRMVEAQLKGVEFISVN
                     TDKQALYTSKAEYKVQIGEKLTRGLGAGANPEVGKRAAEESKDEIVKLLQGADMVFVT
                     AGMGGGTGTGAAPVVAGLAKEMGILTVGVVTKPFAFEGKIRMKNAEGGIAELKSKVDT
                     LITIPNDRLLQIVQKNTSMLDAFAVADDVLKQGIQSISDLIAVEGLINLDFADVTTIM
                     KDKGLAHMGIGSASGETRAIDAARQAIQSPLLETSIQGAKGVLLNVTGGPNLGLFEVN
                     EASTLVMESCDPEANVIFGASIKEDLGDEIMITVIATGFEGLQNGALDLDTKPKSSIR
                     SSLNTTVKQAVKEIEEEVIAEEKIEPPKKASIIEEDDDESMEIPTFLRRRR"
     gene            complement(36339..36692)
                     /locus_tag="PC466_001063"
     CDS             complement(36339..36692)
                     /locus_tag="PC466_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small basic family protein"
                     /protein_id="HDF2768458.1"
                     /translation="MLWVLGGLAFGVVVGYYIPFTYSMDYSIYMSVAILAIMDSIFGA
                     IKSNFEDNYDNVIFITGFIGNAILAILLTYIGEKLGVSLYYVAVLVFGMRLFNNLSII
                     RRYIISNIMNKKRKN"
     gene            complement(36791..37465)
                     /locus_tag="PC466_001064"
     CDS             complement(36791..37465)
                     /locus_tag="PC466_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF881 domain-containing protein"
                     /protein_id="HDF2768459.1"
                     /translation="MKKKIVILGAFILGIFISTYIKSLDPNRVYITLGQTESIESEVE
                     NTKKEIKNLKETLKNNKKTLNEYKEAKKNGNESIQTLMQKELEEVKELSGYSTVTGPG
                     ITITMRDSERELKDGQNPNDLIIHDIDILRVLNDLKKAGARAISINGERVLATSKIKC
                     SGATITVNDTTYGQPFIIKAIGDIDLLSAAINSPESYAKSLKDIYGINIKVQENNGNK
                     VNLFAK"
     gene            complement(37470..38168)
                     /locus_tag="PC466_001065"
     CDS             complement(37470..38168)
                     /locus_tag="PC466_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF881 domain-containing protein"
                     /protein_id="HDF2768460.1"
                     /translation="MKKRFINKSIIIGSVVLGVLVSLQLKIINIENRGMTTFKRGEQL
                     TEELKSLKTEKENLQSEVNSVKKDIETYRGKNNKGEQDILKSEIEKYETLAGYTDVEG
                     TGIKIEINSTKDLGNSDKNDSILYNYDLLLSMINKLNSAQASAISINDQRIVFNTYMY
                     LKEDKLCMNDTVIKEPIIIKAIGDSDTLASALNIKYGIVWEIETYYNAKVKVTKEDNI
                     EINGHSDINKAEGK"
     gene            complement(38191..38931)
                     /locus_tag="PC466_001066"
     CDS             complement(38191..38931)
                     /locus_tag="PC466_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsQ-type POTRA domain-containing protein"
                     /protein_id="HDF2768461.1"
                     /translation="MKKRRKLNTNNVMIVLVFILMLSFCICIIVKSDLFDVKKIDVIG
                     NKRVTKSNIMKELNINLNENIFAYNFKDMKNKLIKNPYIENVEIKRKLPNKIIISLKE
                     KEIFAVLKDEDNYCYIDKKGNLLEELRGSNESKKDLIVDVDYSVDDNKSIKFKNYKTK
                     ENVFKTLNYLKEEGIYRKINYVNLKKESNIEMLTRSNIKILLSNDDNLDYNISRVSKI
                     LIDLQNKNTNGGTINLNYGKLAVYSPEG"
     gene            complement(39201..40427)
                     /gene="murG"
                     /locus_tag="PC466_001067"
     CDS             complement(39201..40427)
                     /gene="murG"
                     /locus_tag="PC466_001067"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HDF2768462.1"
                     /translation="MKVLLSGGGTGGHVYPAIAIANKIRDEHPDAEIIFVGTEKGIES
                     EIVPKYGFELKTVTVQGFKRKIDFDNVKRVFKLFKGLEQSRKIVKKFKPDIVIGTGGY
                     VSGPVLFNASMGKIPAIIHEQNSFPGVTNKILSKTVTKVLTSFEDSHKRFPEAAEDKL
                     VFTGNPVRKEILLSRKNIARKNLSISDEKRMVLCYGGSGGSRKINDAMRLVIKNMVNE
                     DIAFIFATGKSYYDEFMGSISDINLKPYQKVVPYLEDMANALAASDLVIGSAGAISLA
                     EITALGKPSIIIPKAYTAENHQEYNAKSIEKQGAGIAILEKNLTPESLNTAVFKLLGD
                     RELLVDMANASKTIGKPEAIDLIYDEIMKVYNSTQKSTSKKTKKEKVIKEVKEIKKET
                     TPSIEGQAKVIGIKKR"
     gene            complement(40445..41575)
                     /gene="spoVE"
                     /locus_tag="PC466_001068"
     CDS             complement(40445..41575)
                     /gene="spoVE"
                     /locus_tag="PC466_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein E"
                     /protein_id="HDF2768463.1"
                     /translation="MPKENLKKQIDIRMKTEFDGVVFYTTMLLVFVGIVMVFSASFIQ
                     SSFKHNDAYYFLKKNVIYAVLGFIVMIITSRIDYSFWKKNATAIGAIAVVLLLLVLTP
                     LGIEANGAKRWLGIGALTFQPAEIAKFATIILTAKLIEKNYDKIKSLTKGVVPLLVVP
                     GIFFALIILQPNLSTAGTVILVTFVMIFVAGMDMKIVFAMIGSGAALFAALVIAEPYR
                     LSRVTSFLDPFQDPLGKGYQVIQGLYALGSGGLFGLGLGKSKQKYFYIPEPQNDFIFA
                     IIGEELGLIGCIIVIMLFVVLVYRCVRIALKTSNVFACMVVIGIGAQIGIQAALNIAV
                     ATSSMPATGVALPFISYGGTSLTIFMGAVGIVLNISKHVKIN"
     gene            complement(41627..42982)
                     /locus_tag="PC466_001069"
     CDS             complement(41627..42982)
                     /locus_tag="PC466_001069"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HDF2768464.1"
                     /translation="MDLKGKKVLLVGLAKTGISTIKHLDKLGASIIVNDIKDENKLRN
                     ILDELKSINDIKYILGHHPEDVDDIDMVVVSPGVPLDLPFILKLKNSGKYIIGEVELA
                     FKLSNNPIFIGITGTNGKTTTTSLVGEIFSRAKRDTYVVGNIGNPVIDTIETSSEESV
                     LVTELSSFQLESIDEFRPKVSAILNITEDHLNRHHTMEKYIEAKANIFMNQTVEDFCV
                     LNYDDEVVKSLADKCNAKVIYFSRTKKVNGGVYLENNDIIIDIDDKIKFLNKDDVSLP
                     GGHNLENCMAAIAIAYVCKIDLEVIKDVLMTFKGVEHRQEFVRNLDNVIYVNDSKGTN
                     PDSTIKAIQSYDRPIILIAGGMDKGSNFDELLETAKSYVKSLVLLGETASNIENCAKN
                     KGFNDIHIVKDMEEAVKTSYEISKSGDIVLLSPACASWDMYESFEVRGKDFKDNVNNL
                     K"
     gene            complement(43001..43969)
                     /locus_tag="PC466_001070"
     CDS             complement(43001..43969)
                     /locus_tag="PC466_001070"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HDF2768465.1"
                     /translation="MMLGITELTYTALIAFLIVIIIGPIFIPMLRKFKFGQTVRDDGP
                     QTHLAKNGTPTMGGIIMIVAILITGLTRVKVSHDMAVGLICIAGFGFIGFLDDFIKIK
                     LKRSLGLKAYQKIILQVALSFYVAFYQYTSSSSASQLMIPFTDFVINVGILYIPIMMF
                     IIVAIVNAVNLTDGLDGLASGVTLIVSVFFMLFASSIAGNTEVAVLAAATVGACLGFL
                     GFNSYPARVFMGDTGSMALGGAVVAFSVLTNSVLIIPIIGGIYFAEALSVLIQVGYFK
                     ATRKRFFKMAPIHHHFEQCGWPETRVVFIFWIITVVLAWISIIAVF"
     gene            complement(44010..45383)
                     /locus_tag="PC466_001071"
     CDS             complement(44010..45383)
                     /locus_tag="PC466_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HDF2768466.1"
                     /translation="MECLTIKELVLATNGKLIYGDYNDCVSDIVIDSREASAQNAFVA
                     IVGENLDGHTFMKPAYDSGCKTFIKNESNGIKLESSDINLIEVKDTSLALGDISKYYK
                     EKFDIPFIGVTGSVGKTTTRDMIYSAISAKLNILKNEKNLNNHFGVPLTLFNLNKEHE
                     CAVIEMGMSGFNEIKYLVDIVNPKIAVISNIGLSHVEKLGSQEGILKAKMEITSNFDE
                     TNTLIVNGDDKFLSTLKEKEHVYKLKTFGFNKNNDIYCESYTMEEDSLTFICVINGKK
                     EEIFIPTIGEHNIYNAMSAILVGLCLNISLDYIKKGLKNFKGTKMRLDIIKNEKLTII
                     NDSYNASPDSMDAALKILGRYKGRRVAILGDILEMGEISEYGHRLVGKSSMNNTDIII
                     TIGENSVFIGEEAKQLGFNSANIYHFENREDVFNKLNELVKTGDTILVKGSRGMRLEK
                     IVEYLNK"
     gene            complement(45550..47529)
                     /locus_tag="PC466_001072"
     CDS             complement(45550..47529)
                     /locus_tag="PC466_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein D"
                     /protein_id="HDF2768467.1"
                     /translation="MRKVKRISKKRLVLVLILACALFFCLVIRTGYLQLMKGNWLSTK
                     ALEQQTRDIPIEPKRGTIYDRNMKELAVSVTKYTVWCKPVEVEDKKEAAEKVAEILDE
                     DYKDIYALISKKNMALVKVKRWIDDDKASQIRDAKLSGIWVAEDNQRYYPYGNFAPYV
                     LGHTSSDATGISGVEMQYDKKLKGKPGKLIVSTDASGREIPQGMEKYYEPVQGNGLVL
                     SIDEVIQHYTEKAVQKAYELNNAKKVTAIAMNPKTGDILALASKPDYDPNDSRTPIYP
                     YYQEELEKYNDKDKIKGYYQMWRNPAVSDTYEPGSTFKLITSSSALEEGVIKDGEKFT
                     CTGSVTVGGRKIKCWRHYRPHGTQEFKQAVQNSCNPVFVELGSRLGVGKMYDYIESFG
                     LMDKTGIDLPGEAKGILYNEKNVGPVELATISFGQSISVTPIQLITAISSIANGGDLM
                     QPRVVKSYTDNKGNITETVKPKKVRSVISKETSKKMLEIAESVVTEGGGKIAYIPGYR
                     LGGKTGTAQKVIDGKYAPGKYICSFVGIAPCDDPQIVVLAIVDEPTGVSAFGSTTAGP
                     IVKEIMNDSLKYLGVKPVYKEEEKAEYEKKQVKVPDVRNLKIGDAVKALEDAKLKPDL
                     DADIELPEDTKVKDIFPKPGVKVNEDSSITLYFEN"
     gene            complement(47541..47888)
                     /locus_tag="PC466_001073"
     CDS             complement(47541..47888)
                     /locus_tag="PC466_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768468.1"
                     /translation="MKKNYKIHNLNEYKNKKKNNYKKRNKKKIGAKCILLIAIFSVII
                     LNLCGYSKISEMKYDIYYLQKDLRKKEIVLEELKAKETEKTSIKEIELKAKELLNMDY
                     PKDGQIKYIDVDN"
     gene            complement(48374..49309)
                     /gene="rsmH"
                     /locus_tag="PC466_001074"
     CDS             complement(48374..49309)
                     /gene="rsmH"
                     /locus_tag="PC466_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HDF2768469.1"
                     /translation="MEFHHVSVLLNECIENLNIKPDGVYVDCTMGGAGHSKEIVKKLS
                     DKGLFIGFDQDKNAISTAKERLSEYESRVKFVHSNFENIKEELEKIGVYKIDGVLADL
                     GVSSHQLDEADRGFSYMQDAPLDMRMDVRCEFSAYDVVNTYTEDELTKIIKDYGEDNW
                     AKRIAKFIVEERANKPIETTGKLVDIIKKAIPKKARIDGPHPAKRTFQAIRIEVNNEL
                     GVITKMINDASSIMNKGGRICIITFHSLEDRIVKNAFKHLASDCICPQHLPICQCDKE
                     SEVKIITRKPILPSEEEIEVNPRSRSAKLRVAEKI"
     gene            complement(49339..50085)
                     /locus_tag="PC466_001075"
     CDS             complement(49339..50085)
                     /locus_tag="PC466_001075"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HDF2768470.1"
                     /translation="MDRVAFTLFGIDIMWYGILMACGMILGTLIAIKEAKRVGIKDDD
                     VLNIAIIAIPVGLICARIYYVVFNWSYYAQNMSQIFNFRGGGLAIHGGLIGGILAGYI
                     YTKIKNINFLKMADTVILGMPLAQAIGRWGNFINGEAHGGATNLPWGIMVDGVKVHPT
                     FLYESIWDFGIFIVLLLFRKNKKYEGQVIVTYITLYSIGRFFIEGLRTDSLMLGPLRM
                     AQVISLIGVIGGIIAHVYLSKKNKHNISEE"
     gene            complement(50482..51768)
                     /locus_tag="PC466_001076"
     CDS             complement(50482..51768)
                     /locus_tag="PC466_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HDF2768471.1"
                     /translation="MEKIVNDILKEEVYYEKLQNGLDVYFMPKRGFMKKYAILATNYG
                     SNDLEFVPIGEDKKIRVNEGIAHFLEHKMFEQPDGGDAFDKFSKLGVNANAFTNFTMT
                     AYLFSATENFYESLEHLIDYVQTPYFTDENVEKEKGIIAQEIKMYNDDPDWNVYFNCL
                     KAMYVNYPARIDIAGTVDSIYKITKEELYKCYNTFYNPGNMALFVVGDLDVEKVIDVT
                     KKSNNYKVDKLSKSIERFYPEEPESVKEKEVIEKFPISMPMFNIGFKDSNVGLKGKEL
                     LRKEIVTDILVGMLFKKGSKLYEDLYMQGLINENFGAGFSSQVDYAFSIIAGDSKEPK
                     KVKEIILDYIEKSKKEGLSKEEFERTKKKKIGSFIKCFDSINFIGNSFISYVFKDINL
                     LDYLDVIKDITFEEVEERLKEHFKEEYCVISIVEPK"
     gene            complement(51783..53048)
                     /locus_tag="PC466_001077"
     CDS             complement(51783..53048)
                     /locus_tag="PC466_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HDF2768472.1"
                     /translation="MVNTKKIINLGNNINLTLIKTEKFKSNLISLYVQRLLDEKETTK
                     NALIPSIIASGSAKYPSARAISNKLDDLYGSSMGADAVKRGERQVLSFKVINISEKYL
                     DESIFEEVVEFFNEVINNTLVVDGGFKEEYLNIEKENLREKIQSIINDKKEYAQDKCI
                     EAMCKGERYSVSEFGYEDEIDSITSRELYEHYKNILKTSPIDIVVEGNFDEDKVVDII
                     SKNLKFEREEIINIPRADFIKNVDEVKVIDEQMEITQGKLVMGYRANVDYADIDKYYA
                     LVVGSNVLGGGPHSKLFVNVREKESLCYYIFSSIEKYKSIMFISSGIETKDYDKAVEL
                     IKKQVESVKAGDISDEELENSKLALVNSMKSITDNIGGMSDFVFSQSMAKTNSEVQDI
                     ISSIEKVTKKDIVEAIKNIELDTVYFLRN"
     gene            53364..54461
                     /gene="ychF"
                     /locus_tag="PC466_001078"
     CDS             53364..54461
                     /gene="ychF"
                     /locus_tag="PC466_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HDF2768473.1"
                     /translation="MKLGIVGLPNVGKSTLFNAITQAGAESANYPFCTIDPNVGVVSV
                     PDERLNKLQELYNSEKIVPTAIEFCDIAGLVRGASKGEGLGNKFLSHIREVDAIVHVV
                     RCFEDENVVHVDGSVDPLRDIETINLELIFSDIEILERRINKTQKAAKADKTLGSELD
                     LLKSIMSTLEESKCVRTMEFTEDEQTFVNSLDLLTSKPVIYASNVSEDDLADNGENNK
                     YVQQVKAFAETEDAEVVVVCAQIEAEISELDSAEEKKEFLETLGLEQSGLDKLIKSSY
                     ALLGLISFLTAGPKEVRAWTIKVGSKAPQAGGKIHSDIERGFIRAETIAFNDLVEHGT
                     MAAAKEKGLVKLEGKEYIVKDGDVILFRFNV"
BASE COUNT        16939 a         9983 c         5789 g        21866 t
ORIGIN      
        1 tcacgagtgt gcgtagctat tttttaatca atacttaact ttttgttttc accatacatc
       61 aaaacgcacc cctttgcata ataaataaac caccctgcag aacacacgat aaatttataa
      121 ataaatttat cagaagtagc ttactaaaaa tattattcat cctcacttaa acgtttattc
      181 attaatattc tatcacatga cataaataat ttatatgatt tatatagatt tatttattgt
      241 aaattttgga atattaaaac attttattga atagataatt atattacata aaaaatccct
      301 atagaaatct ataaactaat ttctataggg attttggtta actaactatt ctttttattt
      361 ttttataact tttatacctg tcatatggtc atttaagttt tgttcctcta aagatttatc
      421 atctactctg tttatttcta aagctaaagt ttcagacttg atatattcat taaaatggtc
      481 aacagcctta gcaatttcat catcaccaca gtattctatt actatattat ctaatacttc
      541 aaagttatta gattttctta attgctgtac tttagatata aattctctag cataaccttc
      601 attaatcaac tcttcagtta gcttagtatc tagtataaca aaaagattgt tttcaacaga
      661 tacattaaat ccttccttag cagttatacc tattaatact aaatccttat taaattcaaa
      721 agcttcgcca tctaaatcaa ctgttaaagt ctcacctttt tcaagtttat tagcagtttc
      781 atgagcattt aatttactta atgctccaac gaataaattc atcttagaac ctaataatgg
      841 ccctgcttcc ttaaagtttg gttttaaact aaagttcata tactcatcta aatccttagc
      901 aaatattacc tctttaacat taagctcttc ttttattaaa tcaactacat cacttattgt
      961 atcttcaaac ttaccatcta ctaacacttt ttgtaatggt tgacgaactt ttattctttc
     1021 tacttctctt gaagctctac ctaaagtaac taagttttta gctaaatcca ttttttcttc
     1081 taatttagta tctactaact cttcattaca tttaggatat tcagctaaat gaacagatac
     1141 ttctcctgtt aagtttctat acatttcttc tgacatatat ggtgcaaatg gagctatagc
     1201 tctacaaaga ccatgtaaca attcataagt tgtattgtac actgcttttt tatcttctgt
     1261 taattcagtt gcccagaatc ttcttcttga acgtcttata taccagttag ataaatcatc
     1321 atttataaaa tcttgtatca tccttaaagt tttatttaac tcaaatatag ctaaattttc
     1381 ttctacatct ttcattaaat tattgaactt agataatatc catctatcaa gttctggtct
     1441 atctttatat tctacaaaaa attcagttgg atttatatca tctgtgtttg catataaagt
     1501 aaagaagtta tatacattct tcatagtacc tataaattta ctttggattt cttttaatcc
     1561 atccatatca aatttagttg gagtccatgg tggagaaaca tatagtaaat accatcttaa
     1621 tgcatctgct ccatattggt caaacaattc cattggattt actgtatttc ctcttgattt
     1681 actcattttc ttaccatctt tatcaagtac aaggtctgga actaaaacac tcttatatgg
     1741 tgcttttcct aatacaaatg ttgatactgc aagtaatgag tagaaccaac ctctagtctg
     1801 gtctatacct tctgatatat agtcagctgg gaacaattgg tcaaaatttt ccttattttc
     1861 aaatggatag tggtgttgag caaatggcat agccccacta tcaaaccaac agtctataac
     1921 ctctgttact cttgtcattg gttttccaca tttttcacat tttaagtgta tatcatctac
     1981 atatggtcta tgaagttcaa ctgtttctgg atttacatct tctatagctt tttcagctaa
     2041 ttcagctctt gaaccaactg aatctgtatg accacattca catctccata taggaagtgg
     2101 agttccccaa tatctagttc ttgatattgc ccagtcattt agattttcta accagtttcc
     2161 aaatctcttc tctcctacaa aacttgggaa ccattttaca ccattattat tttctattaa
     2221 tttatcttta agtttagtca tctctatata ccagcttggt tttgcatagt atactaatgg
     2281 agtttgacat ctccagcagt gtgggtaatt atgaactact ttttctttgc tatataattt
     2341 attttcagaa gctagccatt ttattatttc aacatctagc ccatcttcca ttacaaatct
     2401 accttcccaa ggagtagatg taaatttacc agtttcatct actggttgaa taactggtaa
     2461 atcatatctt ttacctgtgt tgtagtcatc ttcaccaaat gctggtgctg tatgaactat
     2521 accagttcca tcttcagtag ttacataatc tcctactgta ataaaaaatg cttttttgtc
     2581 aacttctaca aaaggcatta attgttcata ttctaaacct tctaggtctt tacctttcat
     2641 ttcttctaaa acttcataat cttcacctag tactttatca gctaaaggtt tagatacata
     2701 atatacctca tcaccttttt taacttttaa ataatctaca tcagcattta ctgttaatga
     2761 aacatttgat ggtaaagtcc atggagttgt tgtccatgct aagaagtatt catcagcatc
     2821 ttttttctta aatttagcta taactgtatt agtttttact tctttatatc cttgtgcaac
     2881 ctcatgacta gcaagaccag ttccacatct tgggcaataa ggaagtattt tatgcccttc
     2941 atatatatat ccttctttgt tgaatttgtt tagtatccac catacagact ctatatagtt
     3001 attatctaaa gttatatatg gattatctaa atcaacttca taagccattc tctcagtcat
     3061 tattctccat tgtttttcaa atgagaaaac tgactctcta catttttggt taaattcagc
     3121 tattccatat tcttctattt gttgcttgct agtaagacct aactctttct ctacttgtat
     3181 ttcaactggt aatccatgtg tatcccaacc agcttttctc tttacttgat aaccagacat
     3241 tgttttatat ctacaaactg aatctttaag cgttctagat aaaacatggt gtactccagg
     3301 atttccatta gctgttggag gtccttcata gaatacgaaa cttgggtcat ctttcccttt
     3361 ttctaaagtt ttttcaagta tatttatgtc tttccaataa tcaaaaactt gtgcttctgc
     3421 ttgttttaca gaactgtcta ccaatggctt aaatttcgcc atgtaaatca ccctttccta
     3481 ctaaatatta taattccaaa attttttatt ctttcacata aatttaaata ctaaaaaact
     3541 cgcccccttt aaaccaaagg gacgagttat aaatcgcgtt accaccctaa ttctatatgt
     3601 aaactaaata ctagctacat ataacactct aatagtataa cggtactaac cggcacagct
     3661 tagtagaatt taatcgttca gcctgcagct caagagtgat ttttatcttt ataaattcat
     3721 tggttctcag catacccaat tctctgtaaa attatctaaa gataaatgtc tctatcaacg
     3781 cttttaaaaa tttatctgtg tttatatgaa attttataac aaataatttg aatagtcaat
     3841 atatttttga aaaatataat aatttctatt tttcttacat ttttatccta tttttaatct
     3901 ttgttataga tttctcaaac tcacacagtt attctacata aaaaataaac aaattacaag
     3961 cttattctaa agttgtagca gcttcatcat tactataatt atacactgtt gttccttcaa
     4021 atgcatttac acatttttca tctacatcat aaaaaatctc atcaacactt cttatttcat
     4081 cttctaacag tgatttaaat ttatttctaa atatcttaaa ttctttgact aaagcatcat
     4141 actcttttct tatctctatg acacggttat tagcttgttc tataatttgt ctagctttta
     4201 aatcagcttc ttcaacaatt atcttagcct ttttattagc cgcgctacaa gtgtcttctg
     4261 ctgcactttg agcagttatt aaagtagctt ttagtgtttc ttcaatattt tcatacttgt
     4321 ttacttggtc ttgatataac cctaattttt ctttaagagc tgtattttcc ctacatagag
     4381 attcataatc ttccttgatg atatctaaaa attcatcaac ctcttcatct ctataccctc
     4441 ttaaaccttt tttaaactct ttattttcta tctcaattgg agttagcatt acatttcctc
     4501 ccagctataa tttaaattag tccttataca attaatcttg cttgaacttt tatttttcct
     4561 tttttggtaa tatctcctat ttgtgttacc ttagctcttc ctttgcctct aatagaaatc
     4621 aaatcatcat tttttactat tttagaagtt gaagttatct tttcataatt gacatggact
     4681 ttttctccat ttatgtattt tgcactatct tgtctagata tattgtaaat accacttatc
     4741 acacaatcta acctatctga agatactgta aatgatactt ctttatattt tgaagaacta
     4801 ttaacaatat tttctctgga aatttccttt acaattacat tatttcttga aaccttttct
     4861 aagtttacaa ttataaaatc gcaaatatca ctacttacaa ctacttgaca aaagctatca
     4921 tgtataatta tatctccaat tttttctctt tttataccta gacccagtat tgaccctaag
     4981 taatctttat gagatatatt tttaaacttg aaattccctt ctatttgtaa aaatctaaga
     5041 gtatcttcta tatcttcata ttccatgtaa aatggataaa taaatacagt gcttctttca
     5101 gcttgttcat aacctccatc cacactgtat tttatttcat ttgtagaatt taatattgct
     5161 acagcatttt tcacttcata tggattaaga aactccgtag acttaacatc atagtttttt
     5221 atacaactat tagccttgtc tatcacttta aacattttat ttttcaagtc tatatccttt
     5281 atgtgatttg ttagttttaa tttatccatc ctatcacctt agaatataac caatactaat
     5341 tgtcttagga acatcaataa tactattgca attaaaggag aaaaatctat aggtccattt
     5401 gtatatttat acattataga ccttattggc ccttctattg gctctgtaag attttccaaa
     5461 atattaaaaa ttttactttg tcttccattt ggaaaccaag tcatcaagct ttttataact
     5521 atcatccatg ctattatatc taaaagataa taaagtgcaa ttcttattgt tcccatatat
     5581 taaccgcctt tttactattt attttgccaa gggaagaatg ctttactttc taattctttt
     5641 ttcatatttg catctatatc cacattatta ggagctagta taaatattga tttagaaacc
     5701 ttttgtatac ttccatctaa tacataaact gccccattca taaagttaaa tatagattta
     5761 cgaacttcag aattagtcaa tccttccaaa ttcactataa ctgcccttct ttgttttaga
     5821 tggtctgcta tagttgcagc ttcatcataa accttaggtt caactattac aactttcatt
     5881 tggctagttg tatgtaaatt tacaatttta tttgcttttg cagtactaaa gccactgttc
     5941 atttcttctt cttgaactat atcgtccatg ccactttcat attcatcttc aatataatct
     6001 tcttcttcat caactatcca attcttaaat ttagatatta ttccatttga cattattaac
     6061 ttcctcctta aaatttattc aaatttgagt aattattttt tattgtagtt tctttctcca
     6121 aagattgatg ttccaactct aacaatggta gccccttcct ctatagcaat ttcataatcg
     6181 tgactcattc ccattgacaa aacatccatc cctacattag ggatgtttag ttcttttatt
     6241 tgttttgata aatctttaag acctttaaat acacctctta tctcatcttc atcttctata
     6301 aaaggtgcca ttgtcattag accctttatt tttatatttt tatatttttc tgacacttct
     6361 ttgacaaaat ctacaacttc ttctctatca agtccatgct tagactcttc tttagatata
     6421 ttcacttgta ctaagcaatc tatttctctg tttatttgtt ctgcacgttt ttgaatttct
     6481 tcgcataatg caattctatc taaagagtgt atcatacaaa ctttatcgat tatgtactta
     6541 actttattgg tttgcaaagt tcctatcagg tgccagttta atttgtcacc tataatatca
     6601 tactttctag ctaattcttg gggtttattt tcaccaacag aagtgattcc ttccctcatt
     6661 gcctcattaa ctaagtctac atcaacagtc tttgtgactg ccaaaagggt aatctctttg
     6721 ctgtctctat ctactttttt tgcagcttta tcaattttgt ttcttatctc agacaaatta
     6781 tctttaatag aacccattat tatcacctac tttatcctta tatttgtgtt tatactgtta
     6841 ggtcttaaaa ttattttgtc atatagatta acacttgtaa ctccatttat gtcattttta
     6901 taataatcca caaatacaga agattcattc tcataagtta ttccttctaa tatgacaaat
     6961 tttacacttt gtgattgttc atcaattaca tatacaccac gtttattgtc ttttgttttt
     7021 atagaagttt taggtatttt taaacattcc atctgattat atattatatc aaattcttcg
     7081 acacttgtat cctgatttgc aacaatttgg ttacttattt ttaattttac cattatttta
     7141 ttattatttt catatatttt gtaaactttt gcatctaatt tttgctcatg atattcaatt
     7201 attacatttt gatttttttc aaagttatta gaatcttctt tactgatgta tgtagataga
     7261 taattacttt ggtcattggc atctttttct atagttcctt ttacaggaat ctttgcatca
     7321 actttttcat tttttaacac caacgtatct acatttttgc taattatcat tactaatata
     7381 ttaaatacta aatatataag aataccaagt atcactaatc tggtatattt tacctttttc
     7441 aaagactctc cccctataaa attactttca ttataagtac ttcttctaaa aaatgtttat
     7501 tcctttttta taagctaata ttttacgttc taataattat tttttccata ttaaatttat
     7561 tttttatcaa tcttcctata caagactgca ttatttatat ataattgtat tataaagtat
     7621 aagtttaatt tacattttat acattaagct tactttatat gtttttatag ttatttttat
     7681 ttttagatgc aatataaaac caattaagat ttaaaataac ttttgttatg ttgacattta
     7741 tttaggtaat catttacgaa tcgggataac gttatcataa caaaagttta tgtcctaaaa
     7801 aaaatacaag gaggattttc ttatgtcaga aattttatta ggaacaggtt tacttttatt
     7861 ggttctatgt tgtttcacaa tttttagtta caaggcccca tatggtatga aggctatggg
     7921 agctctagca aacgctgcat gtgctacttt cttagtagag gcattcaacc tttctttact
     7981 tggtgatgtt ttaggtatgg aattttttag aagtgttgga gctgctaatg gtagtcttgg
     8041 tggagttgct gctgctatac ttgtgccttt agccttaggt gtatctccag tttatgcagt
     8101 tttaatagga ttatcttgtt tagatttttc tatattatct ggattcgttg ctggatactt
     8161 tgtttctttc ttaattaagt ttatagagaa aaaagtgcca cctggagtgg atttagtggt
     8221 tgtaattctt ctatgtgcac cgctatctcg tcttatagca tcaaatgtag acccattagt
     8281 taatagtaca ctactacaaa ttggacaagt tttgatagaa gctaccaaca ttagccctat
     8341 aataatggga attatactag gaggcataat aacagtagtt ggaacgtctc cacttagttc
     8401 aatggctctt acatctataa ttggtcttac tggtcttcct atggcaatag gagcattagg
     8461 tgcttttggt tcagctttta tgaactcaac actatttgca aaattgaaat taggttctaa
     8521 aaaagatatt atatctgttg ctattgaacc attaacccaa tcagacataa tttcagctaa
     8581 tccaatacct atatattcta ctaatttctt tggaggagcc ttttctggta tcattgtagc
     8641 cttgatgggt cttgtaaaca tgacaccagg tacagctaca cctgtggctg gttttgctat
     8701 aatgtttgct tataatccag ttcaacaagt tcttataaca gctggtttat gtgctttatt
     8761 caatgtaatt gcaggatttt taggttcaaa aatattcagt acctttaaag ttcttactgc
     8821 tggtgaaata cgtggtactg atgtagaaga agaaattgct taaaaaacaa taagatttat
     8881 aaatttatat ctcaagtagt agagttttat attgtaggca attttattaa ttgcaaacgt
     8941 tttatttttt atttatgttt atgattatta tgtgtgttga atatttagat aaatttttat
     9001 ttattatttt tatttagatt tttgtttagt tttttatttg gttgatatat taggaataaa
     9061 aattagtata gtttattatt agttagatag cataactttt tagatacata aaaaatttta
     9121 tattaattag atattattaa aataaaagcg atacatgaat ttttaaatgt ccatgtatcg
     9181 ctttattttt gccataatct taacaactga tttttaaagt ttattatctt aacgaagttc
     9241 attatcttat ataatattta aatgcataga cttctttaat ttaaccatct aaatatttaa
     9301 ttaaatatta ttatatgtaa tataactaat ttttaaatga atgtatagga gctggaatcc
     9361 ttcctcctct ttgagtaaat aattcagatg aatttgtact tataggcatt actggtgctc
     9421 gtcctaaaag tcctccaaat tctaccatat cacctacatc acatcctggg gctggtataa
     9481 ttctaacggc tgtagtctta ttattaatca tacctattgc tgcctcatca gctatcatag
     9541 ctccaagcgt acctgctgta gtatttcctg gcacagctat catatcaaga cctacagaac
     9601 aaatagcagt cattgcttca agcttatcta tacttaaagc acctttaata acagcatcaa
     9661 tcatacctgc atcttcagat actggtataa acgctccact aagtcctcca acatgtgaac
     9721 atgccattac tccacctttt ttaacagcat catttaaaag tgctaatgct gctgtagtcc
     9781 catgagtacc aacaacttca agacccattt cctctaatat atttgctact gaatcaccaa
     9841 tagcaggtgt aggagctagt gataagtcta ttatcccaaa tggaacatcc aatctactag
     9901 aagcttcctt tgccacaagt tgtccaactc ttgtaatttt aaatgcagtc tttttaactg
     9961 tttctgaaac aacatcaaaa ggctctccct ttactttctc taaagctctc ttaacaacac
    10021 cagggccact tacaccaaca tttataattc tatcagcctc accaacacca tggaaagctc
    10081 ctgccataaa tggattatct tctactgcat tacaaaatac tactaatttt gcacaaccaa
    10141 aaccttttgc atcttttgtt aattctgcag tttcttttat gatttctccc atttctttca
    10201 ctgcatccat atttatacca catcttgtag aacctacatt tactgaagca catactttat
    10261 tagtacttgc tagagctttt ggaattgact taattagtat cttatcacct tttgtatatc
    10321 ccttttgaac taatgctgag aatccaccaa taaaatctat acctaaatcc tctgcagcct
    10381 tatccaatgt ctgtgcaaac tttacatagt cattttcatc tgttgcacct gcaataatgg
    10441 aaattggagt tactgatacc cttttattta caattgggat accaaattca cgctctatat
    10501 cttttccaac cttcaccaaa tctttagcag aactcataat cttattgtat attttttctc
    10561 tagctttatc tccatcaggg tctatacaat ctaataaaga aatccccata gttatagttc
    10621 ttatatccaa ctgttcttca tctatcatct ttattgtttc aagtatattt cctacattca
    10681 ctattatcac ctccccttac tgtctactac agattatgca ttgaattaaa tatttcttct
    10741 cgctgaattt ttacatccac tgataatttc ttacctcttt caaccaagtc ctcaaccgtt
    10801 ttctcaaaag aatttaatga tttctctaaa tcaactatca taatcatagt aaaataatcc
    10861 tgtaatattt tttgtgatat atctactatg ttgatatttt gcttgtataa ttcatcacta
    10921 attcctgcca ctatacctgg tttatccttt ccaattactg ttaaaattgc tttcataata
    10981 atatcctccc ttattttttt ataaatctta tatttttaca aattgaacta tgtattaaca
    11041 tatatttcat ttatttgtta gtaaaccact ttttatgtat atatttaata tattttaata
    11101 cctatacatt catttgtcaa ttttttttca atattccatt atttttatac tatttagaaa
    11161 attcatattt tatatatgtt ttctcaacaa taaatacagt tttcataata atgaaaggta
    11221 ttacttagca atctcgtgat tttctaaata atacctctct aaaaattatt tttttaattt
    11281 tatgaattta attatacttt ttctagtatc aggatttaca attaatatag aaccaatcat
    11341 aattggtgtt agtatacaaa ataaaaaaat aatatctttt tttagattat attctttaga
    11401 ttctaattta taattattat ttattattcc atcataatca cttatatttg acttattttt
    11461 atttgtatct tgatttttgt tagaaatact ttccctataa ggaaaagaat gttcattggt
    11521 accaaatact gattttgagc ttaaatcata attatcatca ttttctgtaa ttggattttt
    11581 attgtaaaat cctttttctt tatcagaatt attttcttta ttaccgtctt taggtatatc
    11641 atgaggattt ttattttcat tgctatcagt acttgattct acatcatctt taggagtatt
    11701 tggttgtttc tcatcagaat tattattttc attattattg ttttgattgt tattactatc
    11761 attattttca tttccattat tcccatcttg attgttatca tcctcatctc tatccgggtc
    11821 gtctctacct cctcctccac ggtcaccatc aatatcatca ttttcccgtt catcatctgg
    11881 cgtctcttgg ttgtctccgc ctcccattat aaatcctggt ttaaaaacta tatttgaata
    11941 cccttctttt aatcctccta ccacttttac tctaaaacaa cgcaacttaa aatcttcaaa
    12001 aaaaagtata gcttgatctc taatatcctc ctgttcttca gatatccaat tgattccatc
    12061 gcttgaatat tcaacaaaaa ccttacttgc actatacggc atatcataaa ataaaacagc
    12121 tacatatcca ttttttgtat tttgaaattc cagttccaaa ttgtctattg tttttttctc
    12181 tataacagat acattcaaaa taggaactac atcatcattt attataattt tttctttatt
    12241 taacatttct gttttaaact ttcctgttat atcaaaattt tctccctttt ccaacttttc
    12301 ataataatca gtaaaatccc attctacatc tatatcaagt tgattaccac tagatgtttc
    12361 taataccata tatttgggaa attttatatt ttctatttta tcatctttac ttacttttat
    12421 ttcatcacta aatacaccaa ttcccctatg acaacatttc acaatattat agccagaatc
    12481 tttagctata gagggtataa gctcattata atcatcaatt atataaactt tcttactttc
    12541 tgatataatt gattgtgcca acttattatt atctcttagt aacccacttt cattgttgct
    12601 actatatgct tttattgaag tttcttctat ctcaacatca cctttagaat aaacacctat
    12661 agcatgttct ccattcactt caatatcctt atttagtatt ctaatatcat tttcagtata
    12721 aattcctatt gcatcttttc catttgcctt tattttttca acagattcgt aggatgattt
    12781 aatatgtaag tctcctcctt cttcaacgta taaggctgtc ccatcagtag caattatgtt
    12841 gtttatacca atacttatac ttccaccatt ttctatatgt attactcctt cttttcctcc
    12901 ttcacctatt atattcaatt cattatcatc aataataaat ctcccatgat tttttatcaa
    12961 tattttatat ttgttggtat ctattgtaaa attactgtca taaggaatat aaaatctaaa
    13021 ctcttcatct attaccatat tacaagaaag agtataaact atttcttctt tattattttt
    13081 attttcttga acccaccttt caaaatcttc aagacaattt tcctcttgtc caaaaacttt
    13141 atgtggaaaa cttataaaac acaaaactat tatactcata aaaataaata tctcatactt
    13201 tttcatctta cactcctaga aattttttag ctttgaaaca atcctgtcga aacatatact
    13261 tcacccacta taatttttcc acaattatca attattgtca atttatataa gtatctttat
    13321 taattgttat aaataaaaag ctacttacta aagtaaacag acgtttcact ttaataagta
    13381 gctatatttt tataacaaaa tagttataat attagaactt ccttcattta caattttttg
    13441 taaagtcttt tgcattttaa ctcttatctc ttctggcata gtatataatt tactttgtaa
    13501 ttgctctttt actaagtcat gtagtgactt accaaacata tttgattccc ataaatctgc
    13561 tggttgctct tcaaatactt ccataagata ttttatcatc tcttcacctt gattttgatt
    13621 tccaactatt ggagagacct ctgtagatat atctgctttt ataatatgaa gtgatggtgc
    13681 attggctttt aacttgatac catattgttt tccttgtttc attatttctg gttcttccag
    13741 actaagttct tctaaagaag gagctactac tccatatcct tttatcttgg catctattaa
    13801 agcactttct attttatcat actcattttt aactttagat agtctagtta tcagactaag
    13861 cagttgataa tctccttcaa ttttaaatcc acttttttct tcaaggacat tatagaataa
    13921 atcttgcttt gtctgtaaat caatatttat aacaccttct cctagctcta cattatcaac
    13981 acctgtatct tccaaaaact ctaactcaga aaatccttgt ataatacctt ctatatctct
    14041 tattttacct atatctataa tactttgttt taatgttgtt attatgctac tttttatcca
    14101 atgatttctt tcaagacctt caacccattt tggtaagttg attcttattt ctgtaagtgg
    14161 aaaatcatat aatacagctt ccataacctc ctctatatct tcttcttcca tttcaaccac
    14221 attcattgga agaactggaa cttcatactt ttcttccaat tcacttctaa gcatactcgt
    14281 ttcctcactt tttggactta acgtatttaa aaccactgca aatggttttt taagattttt
    14341 caattcttgt ataactctct cttctggttc tacatagctt tttctgtcaa ttccagtaac
    14401 tgaaccatct gtcaagacaa ctatccctat tgtagaatgg tcttttataa cttttttagt
    14461 tcctatctct gctgcctttt caaatgtcat agcttcttgt gaccaaggag tggatactaa
    14521 tctttgtttt ccaccttcct catgccctaa agctccttca actatgtatc caacacaatc
    14581 taccattctt acttttaaag atactgtgtc ttttattttt atttctacac catctgctgg
    14641 tacaaatttt ggttctactg tcattatcgt tttacctgaa ccactttggg gtatctcatc
    14701 tcttgttcta tcctttttaa attcattgtc tatattaggt ataaccaact tttccataaa
    14761 ttttcttata aaagttgatt ttcctgttct tacaggtcca actactccaa tatatatatc
    14821 cccctgagtc cttttggata tatcttcgta tatgttatta ttcatattat tcctcctata
    14881 catctaatct tattaaatta tatttagagt taagggttaa tattcttaaa atagaaaaat
    14941 aaagaccagc aatattaatt taatttacat atagaaattt gtaaatttca atgtaaatta
    15001 aattaatatt gctggtccaa atagtagtgt attatattaa ctgactttag tagtattttc
    15061 atttgactta ttattcatct caataagttc tttacgtctt tcttttgtca tgttcatcca
    15121 tataaatgta aacaccaatc caattatggc tactatagta agaactatga agtagtacct
    15181 atatccagtt acacccggaa atgcatccaa tatcttccct gctgctaaag gacaaagtac
    15241 ttctggaaga tatcctaatg tagcaactat tcctatagca gttcctgata ttgataatga
    15301 ataattacct tcttcaagta acgaatagtg taaaccttga attgcataca tagatacata
    15361 tattgcaaca catccaatca atagtatata aatcatagat gattttgttg gtgtaaatat
    15421 tacacctaaa agacctgcaa tcataagtat aaatccataa gatataatct ttgatgaacc
    15481 tactttatct ccaagtaatc cagaagcagc tgatgctact ggtctacaat actgagctaa
    15541 tattgagatt gcagatgcaa acaccacagt agctccaaat gcttcagttg aataaggcgt
    15601 aaaataataa aatgacatat tagctgaata tgaacaaaac attattattg ttattatcca
    15661 tgtatgaggc atttttatta ctgcaaaaaa ggcttcttta tcaaattttg ctgatacctc
    15721 tttttcatta tcctttaatt tgaaaaatac taatactcca actattacat ttattgccga
    15781 gtataatact ataatagctg taagaccaga tttatcactt acttttgatg aaatataccc
    15841 aaatagtatc aatactagag atagatgaat tgcattggta attccacgac cactttccat
    15901 aaatccaaaa gcttttcctt gttcattttc agatgctaac attctaacag cttttacaag
    15961 agctggccaa aaagtaagta ttgttgttat tccccataag gcatggatta aaaacacaac
    16021 aatatatgga ggataaagtg ttaatacaag accagatatt cctgtaataa ttaaagaacc
    16081 tgaaagcaat tttctggctg aaatacggtc tgctaaaaaa ccaccaaaaa ggtatgatac
    16141 cattgcaagt agaccataaa tgcttcctaa gcttcccatt tgtgtatttg taagattaaa
    16201 tgcttgtgca aaagtatcat aataataatt ctttaaatat ggtaaagcat atataaatgc
    16261 tcctgctaca aagagtatta tcaagacttt gaaatttttc caaatgcttg gtttatttac
    16321 ttcaactgac atacttcctc cttatgtaaa tacctgtaaa ttttcatgat aattaattat
    16381 tgcttatttt attgtttatt caatatttcg gaatatttat taatatatta ggttaatcta
    16441 tcaataattt atggtgagtt atgagctaaa agtaaactct tttagctcac cataataatt
    16501 atatttttat ttatactaac gtccagagtt attagatatc tttttttcat agttcttcca
    16561 tagcattaaa cctgttatta taacaaaaag acctcctcct atcatttcaa tctcatagat
    16621 tatattatct tttaaagtct ccataactgg tgccgttgag aaaagtatgc caactacagt
    16681 tactacaagt accattctgg caatattgat acaaactgaa tcactttttg caattgaata
    16741 tggtctttct tcatttggtc ttgtctttct aagtctaata taagatgtaa aaagcaagac
    16801 atatggaaat aatgctgtta atgctgtcat agtaacaaga acattgtata tattatctac
    16861 tgatggtaat aagtttgttc ctacaagaag tagactcact attatagcct gaactattac
    16921 tgcatttgat ggtatattgt atttatttgt aacagtcaat tgcttaggaa atacaccttc
    16981 tcttacattt ccaaaaagca tctttactgg acctgctata taaagtatta atgctcctag
    17041 tactgataaa gttattccaa atgctactat tcttataaac caacttccta tacctaaatc
    17101 ttgtgcaact ttagctaatg catctagtat ccctgtagac gctgcaattt tatctggagg
    17161 aagtatcatt gttattgcta ctgaacctaa gatatagatt cctcctatta aaacagccac
    17221 agttaatata gctttaggaa agtttttctt agcattatcc atttcggtta tgaaattagc
    17281 agtcgtttca gctcctgata atgcaaatat tatagcagat atagaaacta atgaattggc
    17341 atctattttt ggtattatat tttggattgt atatatcgat gctgatggag cttttttgag
    17401 aataactaca gacataaatg ccatcactat aagtaatata gcaggaattg tagaacctaa
    17461 tgctcctgta ttcgtaaaaa attttccaaa tgccatccca cgagtactta ctaaggacaa
    17521 cagccaaaat attatgagtg aaagtgctaa aataaacatc ttattgtttg ataaatctgg
    17581 atttccaagc atatatgcaa tatttatagc taaaaatgtc aagaaagaag aataccaaaa
    17641 tatctttgat gtccaattta gccatgacac cataaatccc cacttctctc cataggcttg
    17701 tttaacccat tctccaagtc caccatcttt tggatatgtt gcagccaact ctgcacatat
    17761 aagtgatgca ggaacaaaga atataaaagc aaacaataac caaactggta tagaaccaag
    17821 acccaatcca aaactagagg cagtagattt agctatccat ctaatcccaa atagtgctga
    17881 tatattcata aatactaaat cccaaaatcc aattttcttt ttcactgtaa ttcctccaat
    17941 ttcaaattta ttcaaactca tacacaatgt attgatttaa atatcaagta taagttcttc
    18001 aacacttctt ggataattag ttataattgt agcaccattc ttacctacta ttgctgtatc
    18061 tgagtgtcta aatcctccaa ctccaggtat atatatccct ggctccatag aaaataccat
    18121 tccttcttct aatattaatt cattgtcaaa tcttaaatat ggctcttcat gttctgataa
    18181 acctaaacca tgaccaattc tatgatttga atataactct agaccatact ttgcaacaac
    18241 agctcttgct gcttcatcca ccattcttgc tggtatacca gcttttattg tatctaatcc
    18301 agcttgttga gcctctactg caatcttaaa cacttctttt tgtctttctg ttggtttacc
    18361 tataataaaa gttctttcat tttctgctct atagttttca taccaaacct gtctactatg
    18421 tattactata tctcctcttt gaagtatcct agtattggaa tctaaatgag gttgtgctgt
    18481 tctatcaatc cctgaacaag tccagtttgc aaatcctata tatgtatcag gataattttc
    18541 agaaacatat tttagtaaag cattatcccc cgcaacgtca aactccaatt cactcatccc
    18601 aactctaaca ttttctaaag acccttttat tcctatatca gataggtaac ctgctatctt
    18661 caaaaattct atttcttttg catcttttac atatctcatt tcaaatattt tacttccaac
    18721 atctttgata gcaaatgact tatcagttat atactctgaa aaacttgcag atactatatc
    18781 tttttctatt ccaacagttg ttcctttagg gtatttattt aaaattatat ctaagtaatg
    18841 tttatgtgat attccatgtt ctttcatttc tggtatttca taatacacat atacattatc
    18901 aacttttgca acttctttag catgtaattc ttctaatcca ggtactatta attctatttt
    18961 atcttgagtt actactgtta caattggtct agaataagtt attgctttaa atccactaat
    19021 ataaaattga ttgtctggtt caaatattaa agcaatttca atgctttttt cattcatgta
    19081 ctttctcaat ctttctagtc tcatattatt tgacataatg cacctctttc ttaatattca
    19141 gataatttat tcaatacaac aaggataaat atattatttt aaaattctta atatttttag
    19201 tacttgtcgt atttgcatgt aaattaattt tatttgtgat tattttatca taatcatgat
    19261 tattttgtca atcacgattt tatttttaaa atttttttat attctagtga ttttaaatta
    19321 tctaaaatat aacgagtata cattgtattt tggaatatta ttcttgattt atggtaagtt
    19381 taatgataaa atcacgatta tataaactat attgattatt tgtaggtgaa taaaatgaca
    19441 aataaagaat tacaaaagaa aaggatattg atgtatttca tagaagctgc tcaaaatatt
    19501 atggaaaacg aaggtataga aaatattaca cttcgtaagg ttgcagatat ggctggatat
    19561 aatagttcaa ctctatataa atactttaaa aatttagacc atttaatatc atttgcatct
    19621 ataaaatatt ttaaagatta taacttgaat atttcaagat gtatagaaaa tgtcaatgat
    19681 gaatataaga aatatataat tatgtggaaa ttattttgta agcattcttt tgacaatgct
    19741 caagcttttt atcaggtatt ttttaacttg tctagtgatg aacttagcta tataacaaaa
    19801 caatattatg atatgtttcc agaagattta ggtattcatg atagtgacat atctttaatg
    19861 attacaggag aaagtataaa ggaaagaaat aagatactat taaacaatct tgtagatact
    19921 ggatatatac cagctaaaga tttagacata atcaatgata taattatttc tttttatcaa
    19981 aatctattat tcttaaaaaa gaacacagga aaaaattctg gtgatgatga attaactatg
    20041 aaaatgattt cttctattga atacataata aaacatgcta aataaaatta aaatatggct
    20101 gtctcaaaat agagataagc cttttttatt gttgaaataa taaaaatata tttaatttca
    20161 tataaaaaaa agtgcctcgt aaactaaaaa gttcattttg agacacccct aaaacaaatt
    20221 tattatttat tatacaatag tttatatatc atcacctaaa actacttctt ccatttcatg
    20281 ctttttactt ctcatcatta gttctattcc aacttcttta ggatttgaac ctttatttat
    20341 tacagaatat atagcattag ttataggcat atctatatct aatttttcag caacatcatg
    20401 tgctacttca gtagcagtta tgccttctac aaccatcttt acttctttta aagtatcttc
    20461 taaactcata cctttaccta tgagtatacc agctcttcta tttctactat gcatacttgt
    20521 acaagtaact attaaatctc caatacctga aagacctgca aaggtagaca tattagctcc
    20581 catagcaatt ccaagtctgc tcatttcact aatacctctt gtcataaggg cagcttttgc
    20641 attatcacca taccctaatc cgtcacatat cccagctcca aatgctataa tattttttaa
    20701 tgctcctcca agttctactc caactatgtc tggattcgta taaactctaa gtttagggct
    20761 cataaataaa tcttgtatca tctgtgctat ttttaaatct ttagaagcaa ctactacggt
    20821 agtaggaata tcccttgcta cttcttcagc atgagatggc ccagatagta ttacatatgg
    20881 attttgtggt aattcttctt cacagacttg agataatcta agcccagtcc ctttttcaag
    20941 acctttagct acattaacaa taacttgtcc ttcttttata aatggtttta ttttttggca
    21001 agtacttctt acagcctgtg atggaactgc taaaactatt accttacaat cttttatagt
    21061 tttttctata tcagtactta tagttatatt gtttggaaat aatactcctg gtaaatagtc
    21121 tgtattttct ttagttctgt ttattttttt agcttgttcc tcttttcgag tccacatgct
    21181 cacatcatta cctttttttg caagccctaa agctaatgca cttccccagc ttccagtacc
    21241 taatacacat actttctcca tgtttaacac cacctgagta taatatattt actattcttt
    21301 cttttgacca atttttctct ctgtcccatt taataatcgc tttatatttg ctctgtgatt
    21361 atatattact gatgcagtta agaacagagc tactattaaa ccagctttat tttttaccat
    21421 aatcataaat attggtgaac atcctattcc tacaacagaa cccaatgaaa catactttgt
    21481 tatagctacc accaatataa atactgctag acacattagt gttattactg gatttacagc
    21541 tagcattgca cctagtgaag ttgcaacacc tttacctcct ctaaatccta aaactgctgg
    21601 ccaattatga cctgctacaa cacatataac tgccagatat ccagctaaaa gagtatctat
    21661 tccaaccaat cttgctgcaa attctgatat taaaacagcc attacacctt taagaacatc
    21721 acctaaaaat gtcattgctc ctgctctttt tccaagtgtc ctaagtacat ttgtcgaacc
    21781 tgcattacca gaaccttgag tccttatatc aaccccagca attcgctttg caactatgta
    21841 tgaggtagat atatttccta aaagatatgc aactacagca ataattatat aactaaatat
    21901 ctccactgaa tttcccccct ttagttatat tttaagatat ttatttttta tttttttgtc
    21961 tatactcaaa ctttatggaa gttccttcaa atccaaaatt ttctcttatc ttattctcaa
    22021 ggtatctttg atatgagaag tgagttaaat ccttatcatt tataaacaat gtaattttag
    22081 gaggtctaat gtcagtttga gtcccatagt aaatttttag tcttctacct ttgtcagatg
    22141 gtggttgatt taacattaca gcttctccaa ttacttcatt cagtgctgaa gttgatattc
    22201 tcttagaatg ttcatttgac acatattcaa ctgtatctag tatcttgttc attctttgat
    22261 tagtttttgc agaaacaaat acgattggag catacatcat aaatggaaat ttttctttta
    22321 tatcttttgt gtaattactc atagtcttat tatctttctc tattaaatcc catttattga
    22381 ttacaaatat gcatcctttt ccttcatcat gtgctatacc tgcaaccttt gtatcttgtt
    22441 ctgttacacc ttctaaggca tctattacta tcaatactac atctgctcta tctacagcac
    22501 tcatagctct tattacactg tatttttcta ttgtctcata tattttactt tttcttctaa
    22561 gccctgctgt atctattaga agaaatttct gtccattttt ttcaaaataa gtatcaattg
    22621 cgtctctagt agttcctgca attggactta caattactct ttcttctcca agtatcttat
    22681 tgagtataga actttttcct gcatttggtt tacctgttat agctactctt attatatctt
    22741 cttcatactc tgtatctaat cctgctggaa aattttcaac tatctcatct aataaatctc
    22801 caaatcccat actattggct cctgaaactg caaaaggcgt tccaaatccc aactcataaa
    22861 aatcatatat attatcaaat tgactttgac tatcaatctt attaaccact aagattactg
    22921 gtttttttgt ctttctaagc aattgtgcaa tttctttatc agcagctgtt attccagctt
    22981 taccatcaac tataaaaagt attacatgtg acatgtccat tgcaagcatg gcttgatttc
    23041 tcatttgaga taatattata tcttcgctat caggttcaat tcctcctgta tccactaatg
    23101 taaaatattt atctaaccac tctacttcag caaatattct atctcttgta actccaggtg
    23161 tattttcaac tattgatatc ctttttcctg caaatttatt aaatattgta gacttaccaa
    23221 cgtttggtct cccaactaca gctacaactg gcctacttat actcatttta tttctccttc
    23281 catcttttgt tttctatttt aaaattttat ccacaaagtc ttttccttca ttcaaacaag
    23341 ggataatttt tattctcata agttcttcta attgatttaa ttcaatatta tctaagaaaa
    23401 tttcttcatc tgcttttagc atacttcttg ttatataaag agcttctcct aattctttat
    23461 cttcaagttg ttcttttaaa tccttagctg ttaaaagacc tgatacagtt attgtctctc
    23521 caaaaaactt gtttttgatt tcatatacat ttacttgaag atttttaaac ttgtccatca
    23581 tagcatctgc catactctgt ataaattcat atgcagaatg accagtagct attgatactt
    23641 tcttctctct ttttagaata ttctcaggca atatatttag atactcttca atctctgttt
    23701 ttaacttacg tatcatacct acaccatctt caaactgtaa aaaaccttca tattcttcat
    23761 atccaggcaa ttcactatta gatagtatat aaaattcatc tgataaaaat gcaaatcgag
    23821 tacctaattt ttcaagatat ttctgttgta tttgatgtat ttgctctata gttttacttg
    23881 cgctcttatc attaaatata tttaattcta ctagattttc tctatgcttt gtaatcccaa
    23941 ctggaactat cgcaacactg tttacatatg gataaagttg agctagttct tttattgttc
    24001 tatccaattc ctttccatca tttatacctg gacataaaac aatttgacag ttcatttcta
    24061 tatgagcatc tgccaatctc ttcattatac catataattt tcctgcaaat ttattgctta
    24121 tcattttttg tcttaactct ggattagttg tatgcacaga tatatttata ggacttattc
    24181 tatattttat aatattattt atatcttctt cactcatatt tgtaagtgtg acaaaatttc
    24241 cttgtaaaaa agataatctc gaatcatcat ctttaaaata aagagtttct ctcatacctt
    24301 ctggcaattg gtctataaaa caaaacatac acttatttct acagctttta gcttggtcaa
    24361 ttatcggatt tgtaaattca acacccaaat cttcatcata gtctttttct atctcgtata
    24421 tgtagacttc gccatctttt ttttgtattt ctacatctaa atattcatca cttagtaaga
    24481 atctatactc tattatatca tgtattggct gttcattcac agatataagt aaatctccta
    24541 cctctatacc tatttcttct gcaatactat ctttataaac cttacttata atattattta
    24601 ctttttttac atttacttcc aatattttca ccactctttt gtattcatca atgcttatta
    24661 taatatattt taatatgcaa tttatttatt tattatattt tatgatagca tttttaagca
    24721 tttcatgtca taataacaca ttttaattct aatagtcaat ataagtaaat agctataaaa
    24781 tagattagaa caaataatat tcaaatttaa gtttcttaaa aatttgaata ttatttgttc
    24841 ttaaaaaaat tttataaatt taatgtttta ctatgattaa cgtcccattt gtcatatcat
    24901 gaaccattcc acctacacac tttgacatca acaatgcctt attttgtaag tctttctcat
    24961 catttgcata aaatattgga caacctccac catttttcat attcttatca agtgtaacta
    25021 tagctagggt atattcattt aaacctatat ccattcccat cttatgcact tcctttcttt
    25081 cctattttat aattttttag tgataagttt tttcctttag agcttgaaag tattgggcat
    25141 gactttacag cttccattac tttttccata ttcttatcta ctggtaaata agcaatcatt
    25201 atactttcat cctctttatt tcttctaggt aatggtacga atgaaggttc tccataatct
    25261 ccatataaac ctaaccttga atatatattg tatactattg cttgtctttg accggagtca
    25321 aataatattc ctgcattagc ataatcctta tttttaggaa ttatttgtat tcctacacct
    25381 ctattaatat atacttctct atcacttttt agacctatat ttgttatacc ttttaaatct
    25441 cccaccttta gtatagattc gtccacaaaa ctaatttcag caggcattac atcagctatg
    25501 tctccaatac tttttctagt aagaagtttt tttaatataa aggctaacac taatccacaa
    25561 attgaactta ttaccaaact catcccttca cttattttcg tttctgcaag tattacataa
    25621 tacaatccta ttgttaaaaa agatgtaact atacacatat aatttcttac ttcataggtt
    25681 ctagctatct cttctatgaa tgcagcacct ctctttacaa gttgaacttc ctctaaattt
    25741 tgcaatgtat ttcttctatt tgctctcact tgtctaaatt gttctgctgc tagagataaa
    25801 aatgttatgg atgtataaga acgatttata agagctggaa ccaataatgc tcctaatgaa
    25861 gaagcgacga atgctaatat aagttgagat agtaaaacat ttggttgcgt tggatactgt
    25921 ttttggtcta aattcaacat tataattcta gatgttatac caataataac agcaacaaaa
    25981 aatactctat ccattaaatc actcctaaaa tatttaattt gaaattttac atgtaaatct
    26041 acaaagtctt tctagaaaaa tcactctgct ttccttttga tgtttctatg ataggtgtac
    26101 ttttcactac atctatcatg acatctatat ctttgagtat tggcatatat ggtataacca
    26161 cagtactttt ttctaaattg gtcttagata tagcaacaat atcaacctca tctacatctc
    26221 tatctatccc catatgaata aatagattat gtattatagc ttgtctttgc cctatatcat
    26281 ttactattcc aaatgcacct aaatctcttg gtataacttc tatggccaga cattcatttc
    26341 tatacttttc tcttgtactt tctagaccta tattagttat tattacatca tttaccatta
    26401 aaataggtcc ttcaaaactt atttttgcag gaactatatc tgctatatct gctatactgt
    26461 ttcttcttaa aaatcttcta aaaatcaagc caacaatagc tcctgacaca atagctaaaa
    26521 ttgtgcaatg aaaaaagcta aggtcatact ttcttgcaaa aacgatataa actatcgaag
    26581 atactagtgc agaaaaaaga cttatataac ttctagattc atacgtagat gctatttctt
    26641 caacataagc atctcctttt ggtactaatt cttcattatc aatattcttt agtgttattc
    26701 tttcttgttc cgcaagacct tgaaactgtt gtattgctac tgcaaaaaat gtcaaggctg
    26761 caaactcctt atctataagt gcaggtaatg ctatagcacc taacgaagct gaaagcccag
    26821 atataattat ctgttctaaa taatcttgtg gtcttgatgg gtattgtttg tctgtaactc
    26881 ttaaaactaa tcctctacat aatattccta caactaatgc aactataaaa gagtgtctaa
    26941 ataaatttgc attcaataaa ctttcttcca ttttctcagc tccttctctt atatagtttg
    27001 tgcaaaaaac aaaaaaaatt cccttctatt taaggaaatt tttttgtaat attgtaacta
    27061 taaattcgct accaatgcca agttcacttt ttacttttat acatccattt agtgatttga
    27121 ctatatgctt tgttatagcc aatcctaaac ccgttcctcc tacatcccta cttcttgctt
    27181 tatctaccct ataaaatcgt tcaaatattc gttctacatc ttcttttggt atccctacac
    27241 cattgtctat aactttaatt acgatttttt cttcatcttt taacactaca acttgtacaa
    27301 tcccattatc ttgggtatac tttatagcat tatcaactag gtttaagaac acttgcttta
    27361 tatagtcttt attggatagt atacttattg atttatcatc acatttatat aaaacttcta
    27421 tatttttttc actagctgaa tgttgagtta tttcatatac ctctttaaat acatcatata
    27481 ctacaacatt ttccataaga agagtatctt tattttctac aaatgataac agcaatatat
    27541 catcaatcaa cctttttaat ctatctgatt cgctttctat tatttctaag aatctatttc
    27601 tagtattcac atctatattt tcatttgact ttagtgtttc aacaaaccca cttatagatg
    27661 taagtggtgt tttaagttca tgacttacat ttgcaacaaa atcacttctc atattttcaa
    27721 gtttaacttt tttagtaata tcttctatat ttactatcga acctattatt acgttgttag
    27781 tattctgaag ataaactggg tctaccttta tcttatatac gatatcatct ttagtagtaa
    27841 tattagcagt ttcattatct ttagaaccaa taaattgaag tatttgtttt aatatttctt
    27901 cttcttttat tacaacatta atattatgac cttcaactaa ttgatttggt tcactcttta
    27961 tcatttcttt tgcttcatca tttatcagaa gtatatttcc atttacatct atagccaaaa
    28021 ttccatgaga tatactcttt aatatagatc ttaactgtaa atgtttatac tgtacttctt
    28081 ctaaggtttt atccatattc tttatcatat gattaaaatt tctagctaat tcaccaagtt
    28141 ctcctttggc tgatatgtta agcctagcat gatattcatt attacttact ttttttgaga
    28201 cgtatataaa ctcttttaaa tatttcctta atgttattgt atatcttaca gctaatataa
    28261 caatggctat ggacaacata acaataaaaa aatatatact atttaaatct tccacaagat
    28321 aacactccta aaatataacc tttttaatct attttatacc ctacacctct tatagtctct
    28381 atatattttt ccgatttatc ttcatcttct attttttttc ttaaatatct tatatgaaca
    28441 tctactgttc tagtttctcc atagtattca tacccccata ttttatccaa aagataattt
    28501 cttgaaagta cttttccttt attttgaatt aataatttta acaattcaaa ttccttaaga
    28561 gttaactcta tcttttcaga gcctttggta acttcatgtt ttgataaatc tagttttaaa
    28621 ttgcctgtag taagtatatt gttttcttca cctaagctag tcaaattata tctccttaaa
    28681 acagaactaa tcctagctaa caactctttt atactaaatg gcttagttat atagtcatca
    28741 gcacctattt caagcccttc aaccttgtca ttttccatat ttttagcagt aagcattata
    28801 acaggaatat tttttaagtc cttatcactt cttatttttc tcaaaacttc tattccactt
    28861 atatttggta acatccaatc taaaagtatt aaatctggtt taatttcctt agcctttata
    28921 aatccgtcaa atccatcata tgaataacta acttcgtaat ttgacacctc caaattgaat
    28981 tttaatagct caactatatg catttcatcg tctataacaa gcactttagt attcattaaa
    29041 aagctcctct ctattttatc tgtagtaccg ttcctattcg ttctgatgcc ttattatgtt
    29101 ttctataaga gtggaattta tctgctctac aactagtgca taaatttaaa tttattatat
    29161 tttctttttt aactccacta catctaagca tatactcatt aattttccat aaatctaaat
    29221 agtaacttcc ctcttttatt atatagaact tttcatcatt atttgtaaga attgtgttaa
    29281 atttttctac taaatcttca gacacttcat agcaacatgg tccaattgat ggcccaatta
    29341 tacatactaa atcttcagga actgttttat agcattcaga cattaatttt attgttttat
    29401 gacctatatt actaaaagtc cctctccaac ctgcatgagc cagtcctatg gctttatttt
    29461 tagcatctat aattgatata ggtacacagt ctgctgtaaa cagtaaaagt ggtacttttt
    29521 ccaagtttgt tataagtgca tctccatctc ttcttttccc tatagtatct ttattgacta
    29581 tattaactat atctgaatgt atttgagaat tactagttat attttcaaat gtcaaatcac
    29641 attctttaca tacttttaac atatcttctc tattttttgc atctatattc ttacatgtta
    29701 taactagatt tacagaattt aatttttcat caagttcttc acaattacca cttaaattaa
    29761 catactcttt aatatcttgt acatttttta tatttatata atctttcatc atttgtctcc
    29821 tttttctatc agtatacttt taagttcatt tacaaaagta tttatatctt taaattgtct
    29881 atacacagaa gcaaatctta cataggcaac ctcatctaac tctttcaatt tatccattac
    29941 catctcaccg atttttttgg tttcaatttc ttctataaaa catttattta tttcattttc
    30001 aatatgtaca acaatacttt caatctcttc aatagaaaca ggtctttttt cacatgcttt
    30061 tagcaatcca tattttatct tttctctatc aaaatattct ctactattat cctttttaat
    30121 gaccattaaa ggagttgttt ctattttctc atacgtagta aacctctttt tacatgattc
    30181 acactcacgt cttcttctga tagattttaa atctgtatgt ctagaatcta ttacctttga
    30241 ttctttataa ttacaataag gacattgcat ctatattcct cctttgttta actatatctc
    30301 aaactcatct aagcttaatt ctgaacctat atttactatt attgtatcac aacctatttt
    30361 aagtatatca ttccaaaata taacttcttc atcccctcct cttgaaaaaa aacttctact
    30421 tccatctcca aaaatggtaa atgagactac cttaccttcg tgaatatcca tgtctatgtc
    30481 tattataaac cccatccttt ttccattttt tacatttata atttcttttt ccattatatc
    30541 agaaactcta atcatattgt actcaccctt tctttaaaaa taaatatgta tcgaagtaaa
    30601 aaaaaatgac ctatataggt catttaaatt aaaataatgt ttacagtcca tggattactt
    30661 atacatattt tctcatattt tttaaagcat ttttttcaat tcttgatact tgtgcttgag
    30721 atataccgat ttcatcagca acttctatct gagttcttcc tttgtaaaac cttaaatcta
    30781 ataccaactt ttctctacta tttaatttct taatagcttc tttaagtgat atttcttgca
    30841 accaattttc atcagtatct tttttatctt gaacctgatc cataacaaat attgcatctc
    30901 cattgtcttg atatactggg tcaaacagag atattgggtc ttgtatggca tcaagtgcca
    30961 ttacaactga ttctacttct aattctaatt cctttgctat ttctgatact gtaggttctt
    31021 tagaatttgt tctaattaat ctttctctaa cttgtagtgc cttatatgct atatctttta
    31081 atgacctact tactctaatt gggttattgt ctcttagata tcttctaatt tctcctataa
    31141 tcataggaac agcataagtt gaaaacctta cattttggct taaatcaaag ttatctatag
    31201 cttttataag accaatacaa cctatttgaa ataaatcgtc tatattttct cctctgttgt
    31261 taaacttttt tattacactc aagactaatc ttaaatttcc tcttacaaac tgttgtctgg
    31321 cttcttcatc accatttttt atttgtaata aaagttcctt catttgctta tttttaagaa
    31381 ctggaagttc tgatgtatta acaccacata tttcaacctt attaacttgc atatattttc
    31441 agtcctctct caaaagtatt catctattga aattatttac atttccaatt tttttatact
    31501 ttttaagaag aattaattta acattataca aattttttca tttctttttg caaccttgag
    31561 attattttct tttcaagtct agatatgtag gactgtgata ttccaagcat tccagcaact
    31621 tctttttgtg ttttttcaat acctttatca ataagaccaa atcttaattc cataatttgc
    31681 ttttctctgt cacttaatct gtcaagtgcc ataaccaaca aatctctatc tatttcttct
    31741 tcaattattt tgtatatttc atcattttct gtacccaata catcagataa taaaagttca
    31801 tttccatcta aatctatatt taaaggttca tcaaatgata cttctgtttt ctttttatta
    31861 ttttttctta agtacattaa tatttcattt tctatacatc tcgaagcata agttgccaat
    31921 tttatatttt tattcagttt aaaagtatta actgctttta tcaaacctat agttcctatt
    31981 gaaatcaaat cttctacatc tatacctgta ttttcaaatt ttctcgatat gtagactact
    32041 aatctaagat ttctttctat taaaattgac tttacacttt catctgtttc tagcttttgt
    32101 aaaagctcca tttcttcttc tggtttcaat ggaggaggaa gtatatttgc ccctcccata
    32161 tagtatattc cctttggctt tattattttt aatttaatac ctaacatagt aataaagctt
    32221 attattcttt ctttcaatcg taacattcct tgtccccctt aaattttcac ctaaaatcca
    32281 ggcaatatat ttggattcat tattgctcca tattctctat cattaaaatt tgaaatacca
    32341 agtattatat ttcctatctt ttgctcatct acttctatat agtcagcttt taagcctatt
    32401 attatgcttg tcttattact tccagcatgt ttataaggta ttattctaac tctacctgaa
    32461 gttttatcat ctaaacttcc tataatttct tgtgctttct tcatatctat atcttcataa
    32521 ttaatattta atagtttttc tggaataaat ccttctaaca cactagactt aactattatt
    32581 acatcacttt gacttattgg gtcttttaac aaattaccac tatctactaa agctttacag
    32641 caaaaacttt tttctagtaa gtttatattt atagtctttg taagctcctt aatgtactta
    32701 agcattttca aatctttata aatgtatttt aataattcac aactcacata agtacatgca
    32761 attaagaaag atatttttaa gtgacttatt cctgtaaaat aaattataaa ataagtgctt
    32821 ccagaaataa aaatgtttac tagataaaaa actaacgcta catgaacata atcttttttg
    32881 ctcttgcttc taaatgaaat taaagttatt atgctcatga ttattatttt aaatggtaca
    32941 gtaaatagta tattcattga tggatacaaa taagcaacag aataggcact tcctaaacta
    33001 gcccccaata acttattttt tttaggatta tatcttttag taagaataga agtacaactt
    33061 ataataatat aatttattac taggttttct ataacatagt actcaatata caccatgtat
    33121 ccccccttaa aacctttaaa catattataa gatagtatgt acaaaatttt atgtcacttt
    33181 tgatggtcga atccaaaaca aattctattt aaaaagaaca atgatatatg tcttatactt
    33241 tatgtcgtca aaagatattt ttttaatgcc aaacagatag acttttttgt agaatccaat
    33301 atatctaggt agaagttatt cgctttactt ttggtatatt tataaaaaaa agactacata
    33361 atttaataat atatcaagta aatcttttac ttatataaaa tcaaattata tagtctgtaa
    33421 attcaaatat aaattattgt gctagtaatc catttgcata ttttgcagat tcatttagtg
    33481 cttgttctgg agttatgtct ccagctatca tcatttgaag ttgtttccat aaatattcat
    33541 atatctctac tccatgaggt ccaactgtca atggtctata catatgttta tctcttgtca
    33601 ccatttcttc aaatcttggg tctccttggt atttttcacc tttagcaact ggagctctag
    33661 gtatttcttt gtggaaagct tccattgatt ctttgcttaa catatactca agaagtttaa
    33721 atccaagttc tttattttta catgctgaca ttaatgttaa atcatctact gaagcaaaac
    33781 ttccaactgt cttatcttct aatgatgtta catatcccca gtttaaatcc gggaatgatt
    33841 tatcaaatgt acttgtagca gcagaggata gcattatagt aaatgcagct tttcctggtc
    33901 caaatacact ttcaatcatt tcattactat cttttgataa agcatcttct ggaatatact
    33961 ttttcatatc atttataaag tttgcagctt tcaagccttc tgcattatta aatttaactg
    34021 attttaaatc atcattatat atatctccac cagcttgcca taaatacgga taccagttcc
    34081 agtttaagct tccaaatact ttagaacccc aaccttgtgc aagaccccac tggtcgattt
    34141 ttccatctcc atcagtatct tttgttgctt tttcacagat tcttttaaaa tcatcccatg
    34201 tttttggagg tttttctcct aatttttcta gtatatcttt attgtagtac aatacgcctg
    34261 gattagcagc ttctataggt aaaccataaa taccacccat catttttgca tcatctaagt
    34321 atagataatt atctgaagtt cctgattttt ctaaataagg tgttaaatct tctactgcac
    34381 ccatttctat aaattgaggg aacatctctg catacatgta tcctatatct ggaccttcac
    34441 ctgcacttat tgctgttgca tatttttctg cgtagttatc ccatggtact atctgaaatt
    34501 caatttcaca gttattttct ttttcaaatt tttcaaatat cggcttccat gcatctgcat
    34561 catggtctgt taatggtgca gaccatacaa ctaatttttc tttaccctct ttgcctttag
    34621 aatcttcttt ttttgaacat cctgcaagaa ttgatactga tagaatccct accataacta
    34681 aagaaagaac cttttttagt ttaatcatgc ttaatcccct ttcagacttt aatttgtctt
    34741 tttcctcaaa tgtttacatt taattcagat ttaatattaa caaataagac tactcttgtc
    34801 taatcataaa aaactatact aactcctata actatatttt ttttctatac ctattagatt
    34861 taattcatac taaaaactta ctttttaaat tttatcaata tttaaaaata tttttaagtc
    34921 tagccacaaa ctaactatct aaattgaaca aaataaaaag aagtctattg acttctttat
    34981 aagcttacat attatcttct tcttcttagg aatgtaggta tctccatgct ctcatcatca
    35041 tcttcttcaa ttatacttgc ctttttagga ggctctattt tttcctcagc aattacttct
    35101 tcttcaattt cttttacagc ttgttttact gttgtattta atgaagaacg tatgcttgat
    35161 ttaggtttag tatctaaatc taaggcacca ttttgtaatc cttcaaatcc tgttgcgatt
    35221 actgtaatca ttatttcatc acctaaatct tcttttatag aagctccaaa tataacattt
    35281 gcttctgggt cacaggattc cataactaaa gttgatgcct cattaacttc aaataatcct
    35341 aagttaggac cacctgtaac attaagaagt actcctttag ctccttgtat tgatgtttct
    35401 agaagtggag attgaatagc ttgtcttgca gcatcaattg ctctagtttc accactagca
    35461 ctacctatac ccatatgagc aagtcccttg tctttcatta tagtagtaac atctgcaaag
    35521 tccaagttta ttaacccttc aactgctata aggtctgaaa ttgattgtat accttgtttt
    35581 aatacatcat ctgcaactgc aaaagcatct aacattgatg tatttttttg tactatctgt
    35641 aaaagtctat catttggtat cgttataaga gtatctactt ttgatttaag ttctgctatt
    35701 ccaccttcag cgttcttcat tcttatctta ccttcaaatg caaaaggttt ggtaactaca
    35761 cctactgtaa gtatccccat ttcttttgcc aagcctgcaa ccactggagc agctcctgta
    35821 ccagtaccac cgcccattcc ggctgttaca aagaccatat cagctccttg aagtaacttt
    35881 actatttcat ctttactctc ctcagcagct cttttcccta cttctggatt tgctcctgct
    35941 ccaagtcctc tagttaattt ttctcctatt tgaactttat attcagcttt tgatgtatat
    36001 aaagcttgtt tatctgtatt tactgatata aattcaacgc cttttagttg agcttctacc
    36061 attctattga cagcattgtt tccaccgcca cctacaccta ttactttaat ttgtgcacat
    36121 tcttctaatt ctacgtcaaa gtttagcatc ataaaccccc ttctctcatg attcaaagtt
    36181 atcgtatgta ttaattatat cattttcttc ttttattttg ttaaccttta agtaacatat
    36241 tccacaaaaa cgtaaatttt cctttttaaa tttcttactt atattgtcaa atattactct
    36301 ttaagtataa aataatttac gtatatatta aatgctcttt aatttttacg ttttttgttc
    36361 ataatattac taataatata tcgtctaatt atagataagt tattaaacaa tctcatacca
    36421 aaaactagta cagcaacata gtaaagagaa actcctaact tttctcctat ataagtcaat
    36481 aatatagcca atatagcatt acctatgaaa ccagtaataa aaattacatt atcatagtta
    36541 tcttcaaaat tggattttat cgctccaaaa atagaatcca ttattgcaag aatagctact
    36601 gacatatata tggaataatc catagaatat gtaaatggaa tatagtaacc tactactaca
    36661 ccaaatgcta atcctcctaa aacccacaac ataaatcttc acctctttat tttactttga
    36721 aacacaacta cattacaatc ctttttatta atttttttta ctttttcttt atttttttgt
    36781 atttttcgtt ttattttgca aataaattca ctttattccc attattttcc tgaactttta
    36841 tattaattcc atatatatcc ttaagagatt tagcatatga ttctggagag tttatagctg
    36901 cactcaataa atctatatct cctatagctt ttattataaa tggttgtcca tatgtagtat
    36961 catttactgt aatagtagct cctgaacatt ttatcttact tgttgctagt actctttccc
    37021 catttataga aattgctctt gctccagcct tttttaaatc atttaaaact ctcaaaatat
    37081 ctatatcatg tataatcaaa tcatttggat tctgtccgtc ttttaactct ctctcactat
    37141 ccctcatagt aatagttatg cctggccctg taacagttga ataaccactt aattctttaa
    37201 cttcttcaag ctctttttgc ataagtgttt ggatagattc atttccattc ttttttgctt
    37261 ctttatattc attcaaagtt tttttgttgt ttttaagagt ttcttttaaa ttttttattt
    37321 ctttttttgt attttctacc tcactttcaa tactttcagt ttgacctaat gttatgtata
    37381 ctctatttgg gtctagtgat tttatataag ttgatatgaa aatgcctaat atgaatgctc
    37441 ctaatataac tattttcttt ttcatactat tatttcccct ctgctttgtt tatatcacta
    37501 tgaccattta tttctatatt gtcttctttg gtcactttta ctttggcatt ataatatgtt
    37561 tctatttccc agacaatacc atactttata ttaagtgccg aagccaatgt atcagaatca
    37621 ccaattgctt ttattataat tggttctttt atgacagtgt cattcataca aagcttgtct
    37681 tcttttaaat acatatatgt attaaaaact attctctggt cgtttataga tatggcactt
    37741 gcttgtgctg aatttaattt atttatcatt gacaataata aatcataatt atatagtata
    37801 ctatcatttt tatcagagtt tcctaagtct tttgtagaat ttatctcaat ttttatgcct
    37861 gttccttcaa catctgtata tccagctaat gtttcatatt tttctatttc tgacttaagt
    37921 atgtcttgtt ctcctttatt gtttttgcct ctataagtct ctatatcttt cttcacacta
    37981 ttaacttctg attgtagatt ctctttttct gtttttaaag atttaagttc ttctgtaagt
    38041 tgctctcctc ttttaaaagt tgtcatccct ctattttcta tattaataat tttaagttgt
    38101 aaactaacaa gaacacccaa tacaacactt cctatgatta tacttttatt tataaatctt
    38161 tttttcaata tatcacttcc ttacaattgt ctatccttct ggactataca ctgccaactt
    38221 tccatagtta agatttatag tccctccatt agtattttta ttttgcaggt caatcagaat
    38281 tttacttacc ctagatatat tataatctaa gttatcatca ttagaaagta agatttttat
    38341 attacttctt gtaagcattt ctatattgct ttcttttttt aagtttacat aatttatttt
    38401 tctataaatt ccttcttctt ttaaataatt taaagtttta aatacattct ccttagtttt
    38461 ataattttta aattttatag atttattatc atcaacgcta taatctacat ctactatcaa
    38521 gtctttttta ctttcattag aacctcttag ttcttccaat aaatttcctt ttttatctat
    38581 ataacaataa ttatcttcat cttttaatac tgcaaatatt tctttttctt ttaaacttat
    38641 aattatctta ttgggaagtt ttctttttat ttccacattt tctatatatg gattttttat
    38701 aagtttattt ttcatatctt taaaattgta tgcaaaaata ttttcattta gatttatatt
    38761 tagttctttc attatatttg atttggtcac cctcttattt ccaattacat ctattttctt
    38821 tacatcaaat aaatcacttt ttacaattat acatatacaa aaagataaca taagtataaa
    38881 aactaaaact atcatgacat tattcgtatt taactttctt ctttttttca aatataatca
    38941 acccctttgg ttaataaata cacctttaga gcttgttttt cctacaaaaa aattataata
    39001 tttaaagtca aatttttgca ttttattaca taacatccaa ataaggtatt aaattttata
    39061 aataaatcaa tatttcatca aaataaacat agtatactac atactattta tatatttaaa
    39121 tctgtataca tacaaataaa cccctaattt ataataattt agaaaatcta atatattata
    39181 aattaggggt aaatatttac ttatcttttc tttattccta ttaccttagc ttgaccttct
    39241 atacttggag tcgtttcttt ttttatttct tttacttcct taataacttt ttcctttttt
    39301 gtttttttag aagttgactt ttgtgttgaa ttgtatactt tcattatctc atcatatata
    39361 aggtctatgg cttcaggctt acctatagtt ttacttgcat ttgccatatc aactaaaagt
    39421 tctctatctc ctaaaagttt aaatactgct gtatttaggc tctctggagt tagatttttt
    39481 tctaaaatag caattcctgc cccttgtttt tctatactct tggcattata ctcttgatga
    39541 ttttcagcag tataagcttt aggtattatt atagatggct ttccaagagc cgttatctca
    39601 gctaatgaaa ttgctcctgc gctacctata accaaatcac ttgctgcaag tgcatttgcc
    39661 atatcttcta agtaaggcac aactttttgg tatggtttaa gatttatatc gctaatactt
    39721 cccataaatt catcataata gcttttgcct gtagcaaata taaaagctat atcttcattt
    39781 accatattct ttattacaag tctcattgca tcatttattt ttcttgaacc tccactacca
    39841 ccatagcaaa gtaccattct tttttcgtca cttattgata gattctttct tgcaatattt
    39901 tttcttgata ataaaatttc ttttctaact ggatttcctg taaaaactaa tttatcttct
    39961 gctgcctctg gaaatctttt atgcgaatct tcaaaacttg taagtacctt tgtaactgtt
    40021 ttagataaaa tcttattagt tacaccagga aaagaatttt gctcatgtat tatggctggt
    40081 attttcccca tagatgcatt aaataaaaca ggtccactaa catatccacc agttcctata
    40141 actatatctg gtttaaattt cttaacaatc tttcttgatt gctccaaacc tttaaaaagc
    40201 ttaaaaactc tttttacatt atcgaaatct atttttcgct taaaaccttg aactgttaca
    40261 gtctttaatt caaatccata cttaggaact atttctgact ctattccctt ttccgtccca
    40321 acaaaaatta tctcagcgtc tggatgctca tctcttattt tgtttgcaat agctatagct
    40381 ggatacacgt gccctccagt tccaccgcct gataataaaa ctttcatcaa atcatcatct
    40441 cctgttaatt aattttgaca tgctttgaga tgtttaacac tattcctaca gctcccataa
    40501 agatggtgag tgaagttcct ccataactta taaatggtag tgctacacct gtagctggca
    40561 ttgatgatgt cgcaactgct atatttaaag ctgcttgtat tccaatttgt gcacctatac
    40621 ctataacaac catacaagca aatacattag aagtcttcaa agctattctt acacatctgt
    40681 agactaaaac tacaaatagc ataataacta ttatacaacc aatcaatcct aactcttctc
    40741 ctattatagc aaatataaag tcattttgtg gctctggtat ataaaaatac ttttgtttac
    40801 tctttcctaa gcctagacca aacaatccac ctgaacctag tgcatataga ccttgtatta
    40861 cctgataccc cttaccaaga gggtcttgaa aaggatctaa aaatgatgta acacgactaa
    40921 gtctataggg ttcagcaatt actaatgcag caaataaagc agccccactc cctatcatag
    40981 caaatacaat tttcatatcc attccagcaa caaatatcat tacaaaagta actagaatta
    41041 cagtacctgc tgttgacaaa tttggctgaa gtattatcaa cgcaaaaaat atccctggaa
    41101 ctacgagaag tggtacaaca ccttttgtca aagattttat tttatcataa tttttttcaa
    41161 ttaattttgc agttaatatt attgtagcaa actttgcgat ttctgcaggt tgaaatgtta
    41221 aagctcctat tcccaaccat ctttttgctc cgtttgcttc tatccctaaa ggggtcaaaa
    41281 ctaacaataa taatactact gctatagctc caattgctgt agcatttttc ttccaaaaac
    41341 tataatctat tcttgatgta ataatcataa ctataaatcc aagtacagca tatattacat
    41401 tcttttttag aaaatagtac gcatcattgt gtttaaatga agattgtata aaacttgcac
    41461 taaacaccat aactattcct acaaatacta aaagcatagt agtgtaaaac actactccat
    41521 caaattcagt cttcatcctt atgtcaattt gttttttcaa attttcttta ggcatccaac
    41581 taatctacct ccattcttcc atttaagtaa gtttagaggt aagagattat tttaaattgt
    41641 ttacattatc tttgaagtct tttcctctta cttcaaaact ttcatacata tcccaacttg
    41701 cacaagctgg tgaaagaagc actatatctc cactttttga aatttcataa gaagtcttaa
    41761 ctgcttcttc catatctttt actatatgta tgtcattaaa tcctttattt ttagcacaat
    41821 tttctatatt tgatgcagtt tctcctaata agaccaatga tttaacatat gactttgcag
    41881 tttcaagaag ttcatcaaaa ttacttccct tatccatccc ccctgctata agtattatag
    41941 gtctatcata agactgtata gcttttatag tggaatctgg attagttccc tttgaatcat
    42001 ttacatatat tacattgtct aaatttctta caaactcttg tctgtgttcc actcctttaa
    42061 atgtcataag tacatccttt ataacttcta aatcaatttt gcagacatat gctattgcta
    42121 tagctgccat acaattttct aagttatgac ctccaggtaa acttacatca tctttattta
    42181 gaaatttgat tttatcatct atatctatta ttatgtcatt attttctaaa tatactcctc
    42241 catttacttt tttagttctt gaaaagtaaa ttactttggc attgcattta tcagctaaag
    42301 attttactac ctcatcatca tagtttaaca cacagaaatc ctcaacagtt tggttcataa
    42361 atatatttgc ctttgcttct atgtattttt ccatagtatg gtgtctattt aagtggtcct
    42421 ctgtaatatt taatattgcg cttactttag gtctaaattc atctatactc tcaagctgaa
    42481 aactgcttag ttcagttact aacacagact cttcacttga agtttctata gtatctatta
    42541 caggatttcc tatattacca actacatatg tatctcgttt tgctcttgaa aaaatttctc
    42601 ctaccaaact agttgtagtt gtctttccat ttgtacctgt aatccctata aaaattggat
    42661 tattcgatag tttaaaagct aattctacct caccaattat atacttgcct gaatttttta
    42721 atttcaatat gaatggtagg tctagtggta cacctggaga cactacaacc atatctatat
    42781 catctacatc ttctgggtga tgtcctaata tgtattttat gtcatttata gatttcaatt
    42841 catcaagtat atttctcaat ttattttcat cttttatatc atttacgatt atacttgcac
    42901 ccaatttatc taaatgttta attgtagata taccagtttt tgcaagtcct actaataaaa
    42961 ctttttttcc ttttaagtcc atttttcatt ccccctagcc ctaaaatact gctattatac
    43021 ttatccaagc taaaacaact gttataatcc aaaaaataaa tacaactctt gtttctggcc
    43081 aaccacactg ttcaaagtgg tggtgtattg gagccatctt aaagaatctc tttcttgttg
    43141 ccttaaaata tccaacttga atcaaaactg atagagcctc cgcaaaataa attcctccaa
    43201 ttataggtat tataagcact gagttagtta gaactgaaaa tgctacaact gcacctccta
    43261 atgccattga acctgtgtcg cccataaaca ctctagccgg atatgaatta aatcctaaga
    43321 aacctaaaca tgctccaaca gttgctgctg ctaaaactgc gacttctgta tttccagcaa
    43381 tagaacttgc aaatagcata aagaatacag aaactattaa tgttactcct gatgctaatc
    43441 catctaatcc atcagtcaag tttacagcat ttactattgc tacgattata aacatcatta
    43501 ttggtatata taatattcca acatttatca caaaatctgt aaatggtatc ataagttgtg
    43561 aagcacttga tgatgatgta tactgataaa aagcaacata aaaagataat gcaacttgaa
    43621 ggattatttt ttgatatgct tttagtccaa gtgatctttt tagctttatt tttataaaat
    43681 catctaaaaa gccaataaaa ccaaaacctg caatacatat aagacctact gccatatcat
    43741 gactaacttt tactcttgta agtccagtta ttagaattgc aacaatcatt ataattccac
    43801 ccatagtagg tgttccgttt ttagctagat gtgtttgggg tccatcatct ctaactgtct
    43861 gaccaaattt aaattttcta agcattggta taaatattgg tcctattata attactatta
    43921 aaaacgcaat caatgcggtg tacgtaagct ctgttattcc taacatcata aaactcctct
    43981 cccttgtcaa ttaactcatt agtttaagct tatttattta gatattcgac tattttttct
    44041 aatctcatgc ctcttgagcc ttttactaaa atagtgtctc ctgtttttac taattcattt
    44101 aacttgttaa acacatcttc tctattctca aagtgatata tattggctga attgaatcct
    44161 aattgttttg cttcttctcc aataaacact gaattttcac ctatagttat tataatatca
    44221 gtattattca tagatgattt tccaactaat ctatgaccat actctgaaat ttcacccatt
    44281 tctagtatat ctccaagtat cgctaccctt ctacctttat atcttccaag tatctttaaa
    44341 gcagcatcca tagaatctgg actagcatta tatgaatcat taattattgt taatttttca
    44401 ttttttatta tgtctagtct catttttgtc cctttaaaat tttttaaacc tttttttata
    44461 taatctaaag aaatatttag acacaaacca actaatatag cagacattgc attatatata
    44521 ttatgttctc ctattgttgg tataaatatt tcctcttttt tcccatttat tacacatata
    44581 aatgttaaac tatcctcttc catagtataa ctttcacaat aaatatcatt gtttttatta
    44641 aagccaaatg tttttaactt atatacatgt tctttttctt ttaatgtaga taaaaactta
    44701 tcatctccat ttacaattaa agtatttgtt tcatcaaagt ttgaagtaat ctccatcttt
    44761 gctttcaaaa taccctcttg tgaacccagt ttttctacat gtgataatcc tatattcgat
    44821 atgactgcaa ttttaggatt tactatatcc actaaatatt ttatttcatt gaatccagac
    44881 atacccatct ctattacagc acactcatgt tctttattta gattaaataa agtcaatgga
    44941 actccaaaat gattatttaa gtttttttca ttttttagta tatttaactt tgcagatatg
    45001 gcagagtaaa tcatatctct agtagtagtt tttcccacac tacctgtaac acctataaat
    45061 ggaatatcaa atttttcttt atagtatttt gaaatatctc ctagagccaa agatgtatct
    45121 tttacctcta ttaaatttat atccgaactt tctaatttta ttccattact ttcatttttt
    45181 ataaaagttt tacatccact atcatatgca ggcttcataa atgtatgccc atctaaattt
    45241 tctccaacta tggctacaaa tgcattttgg gcacttgcct ccctgctatc tataactata
    45301 tcacttacac agtcattata atctccatat attaacttcc cattagttgc aagtactaac
    45361 tcttttattg ttaagcactc cattattaaa ctcctccttt aaaaccttag ctatattctc
    45421 ttagcaacaa aaggcaatgt ataccgttat atatacattg cctacgataa ctcttaactt
    45481 tataattata tactatattt ctgttttttt gaagatgttt atgggtatat gttaattatc
    45541 tgttactttt tagttttcaa aatatagggt tatacttgag tcttcattaa cttttactcc
    45601 aggttttggg aatatatcct ttacctttgt atcttctgga agttctatat ctgcatctaa
    45661 gtctggtttt aacttcgcat cctccaatgc ctttacagca tctcctattt ttagatttct
    45721 tacatctggc actttaactt gcttcttttc atactcagct ttttcttctt ctttatatac
    45781 tggtttaact cccaaatatt ttaaagagtc attcattatt tctttcacta ttggtcctgc
    45841 tgtagtacta ccaaatgcac ttactcctgt tggttcgtca acaatagcaa gaactactat
    45901 ttgcgggtca tcacaaggtg ctattccaac aaatgaacat atatactttc ctggagcata
    45961 cttaccatct ataacttttt gagctgtacc tgttttacca ccaagtctat accctggtat
    46021 atatgctatc tttcctccac cttcagttac aactgattct gcaatttcta acattttttt
    46081 agatgtttct ttagatataa cacttcttac tttttttggt tttactgttt cagttatatt
    46141 tcctttattg tcagtataag attttaccac tcttggttgc attaaatctc caccattagc
    46201 tattgatgat atagctgtta taagttgtat tggagttact gatatagatt gaccaaatga
    46261 tattgtagcc aattcaactg gtcctacatt tttttcgtta tacagtattc ccttagcttc
    46321 tcctggtaaa tctatacctg tcttatccat aaggccaaat gattctatat aatcatacat
    46381 ttttccaaca cctaatctgc ttcctaattc aacaaatact gggttgcaag agttttgtac
    46441 tgcttgttta aattcttgtg ttccatgagg tctgtaatgt ctccaacatt taatctttct
    46501 tcctccaaca gttacactac ctgtacatgt gaatttttct ccatctttaa ttactccctc
    46561 ttcaagagca ctggaagatg taataagctt aaatgtagaa cctggttcat atgtatcact
    46621 tactgctgga tttctccaca tttgataata gccttttatt ttatctttat cattatattt
    46681 ttcaagttct tcttgataat atggatatat tggcgttctt gagtcattag ggtcataatc
    46741 tggttttgat gctaaagcaa gtatatcacc tgttttaggg ttcatagcta ttgcagtaac
    46801 cttttttgca ttatttaact cataagcttt ctgtactgct ttttcagtat agtgttgaat
    46861 tacttcatct atagacaaca caagaccatt accttgtaca ggctcataat atttttccat
    46921 tccttgtggt atttctcttc ctgaggcatc agtacttact ataagttttc caggctttcc
    46981 ttttaacttt ttatcatatt gcatttctac accagatata cctgttgcat ctgaagaagt
    47041 atgtcctaac acatatggcg caaaattccc atatgggtaa tatctttgat tatcttctgc
    47101 tacccatatt ccacttaatt tagcatctct tatttgactt gccttatcat catctatcca
    47161 tctttttact tttacaagag ccatattttt tttgcttatt aaagcgtaaa tatctttata
    47221 atcttcatcc aaaatctcag ctaccttttc agctgcttct tttttatctt ctacttccac
    47281 aggtttacac caaacagtat acttagttac acttactgct aattctttca tatttctatc
    47341 atatatagtt cctcttttgg gttctattgg tatatctctt gtttgttgtt ctagtgcttt
    47401 tgtactcaac caatttccct tcataagttg taggtaccca gtcctaataa caaggcaaaa
    47461 aaacaatgca catgctagaa taagaacgag taccagcctt ttcttactta tcctctttac
    47521 ttttctcaaa tctattcccc ctagttatcc acatctatat actttatttg tccatctttt
    47581 ggatagtcca tattgagcaa ttccttagcc tttagctcaa tttcttttat tgatgttttt
    47641 tcagtttctt ttgcctttag ttcctctaat actatctctt tttttcttaa atctttttgt
    47701 aaataataga tatcgtactt catttccgag atttttgaat aaccacatag attcaatatt
    47761 attactgaaa aaattgcaat cagtaaaatg catttagctc ctattttttt cttatttctc
    47821 tttttataat tattcttttt tttattttta tattcattta gattatgtat tttataattt
    47881 tttttcaaat tctcaccccg atagtatata gtttaaattt tcctctatac tatatttgtt
    47941 attaatcata tttcttcctc taaaatttca tcgctaaatt aatacactat tacacaatct
    48001 aattgtattt ttttctatac acaacaaaaa cctataaatt cacttatact tttatatgaa
    48061 tctataggtt agatattaat ttctatttat ttttatcact tctagtattt ttagataatt
    48121 tcttccataa atataatatg taactaacta tctactctct gattcctaag ttctccatta
    48181 tattacttaa taccatctat atctatattt ttatatctaa attttcatta tatatctcaa
    48241 taacaaagaa catttcttat agtgttaatt gttttttaat tgctttacca gttcaacaaa
    48301 atatataata ctttttaatt aattatagta atcttatttt atatataaga ttattcttta
    48361 gccttataac tacttatatt ttttctgcta ctcttagctt agcacttctt gaacgtggat
    48421 ttacttctat ttcttcctca ctaggtaata taggttttct agttattatt ttcacctcag
    48481 attctttatc acattggcat ataggtaaat gttgtggaca tatacaatct gatgctaaat
    48541 gcttaaatgc atttttcact attctatctt ctaatgaatg gaatgttatt atacatattc
    48601 ttccaccttt attcattata gaagaagcat catttatcat ctttgtaatt actccaagtt
    48661 cattatttac ttctattcgt attgcctgaa aagttctttt agctgggtga ggtccatcta
    48721 ttctagcttt cttagggata gcttttttaa ttatatctac taattttcct gtagtttcta
    48781 ttggtttgtt tgctctttct tcaactataa atttagctat acgcttagcc cagttatctt
    48841 ctccataatc ttttattatc ttagttaatt catcttctgt ataagtattt acaacatcat
    48901 atgcagaaaa ctcacaccta acatccattc tcatatcaag tggtgcatct tgcatataag
    48961 aaaatcctct atcagcttca tcaagttgat gagatgaaac tcctaaatca gctaatacac
    49021 catcaatttt gtaaactcct attttttcta attcctcttt tatattttca aaattgctgt
    49081 gaacaaactt cactctactt tcatattcac tcaatctctc ttttgctgtg cttatagcat
    49141 ttttatcttg gtcaaaccct ataaataatc ccttatctga cagttttttt actatttctt
    49201 tagaatgtcc tgctcctccc atagtacagt caacatacac gccatctggc tttatattta
    49261 aattctctat acactcattt aaaagaactg atacatgatg aaattccata gttacctccc
    49321 ttaaattcac tttttaaact attcttcact aatattatgt ttatttttct ttgataaata
    49381 aacatgtgca attatgccac caataactcc aattagactt ataacttgtg ccattctaag
    49441 tggtcctaac attaaactat ctgttcttaa tccctctata aaaaatcttc ctattgaata
    49501 taaagttata taagtaacta taacttgacc ttcatatttt ttattttttc taaatagtaa
    49561 taaaactata aatattccaa aatcccatat ggactcatat aaaaaagttg gatgtacctt
    49621 tactccatca accattattc cccaaggtaa attggtagca cctccatgtg cttctccatt
    49681 aataaaattt ccccatcttc caatagcttg tgctaaaggc attccaagta taactgtatc
    49741 agccattttt aagaagttaa tatttttaat cttagtgtat atataaccag ctaatattcc
    49801 accaattaac cctccatgta tagcaagtcc accacctcta aaattaaaaa tttgagacat
    49861 attttgagca tagtaactcc aattaaatac aacataatag attcttgcac agattagtcc
    49921 aactggaatt gctattatag ctatatttaa tacatcatca tctttaattc ccactctttt
    49981 tgcttctttt attgctatta aagttcctaa aatcattcca catgccataa gtattccata
    50041 ccacatgatg tctatgccaa acagtgtaaa tgctactcta tccataacgt cacctctttg
    50101 tattaattga aaatatttcc aaagcaatat gctataatta caattaattg taattatact
    50161 aaattatgat aacacattaa tgttaattct acaaaaaata ttaaaattta ttctacaaat
    50221 ccctacacta tattatacta atataattac tataaaattt tttaaactga atctctcatg
    50281 actaaagtta caagtgtaca tagatatttt ttaatcaaaa agattgatgc atatatacat
    50341 caacctcttc tattccttat ctatagctct taaattttta cctcaattta tataaatata
    50401 ttttataaat ttgttttacc aaaataaaca tttaaaaaca taaataatac ttaattagtt
    50461 attcttatta tgattaagtt tctatttagg ttctacaata gaaataacac aatactcttc
    50521 tttaaaatgc tcttttaatc tttcttcaac ttcctcaaaa gtaatatctt taataacatc
    50581 taaataatcc aatagattta tatccttaaa aacataagat ataaaactat tacctataaa
    50641 gtttatagaa tcaaagcact taataaatga ccctattttt ttctttttag ttctctcaaa
    50701 ctcttctttt gataatcctt ctttttttga tttttctata taatcaagaa ttatttcttt
    50761 tactttttta ggctctttag aatctccagc tattatgcta aaagcataat ccacttgaga
    50821 cgaaaatcca gctccaaaat tttcatttat taaaccttgc atatacaaat cttcatagag
    50881 cttacttcct tttttaaata acatccctac aagtatatca gttacaatct ctttacgtaa
    50941 aagttctttc ccttttaaac caacattact atctttaaaa cctatgttga acataggcat
    51001 agatataggg aatttttcta taacctcttt ttcttttaca ctttctggtt cttctggata
    51061 aaatctttct atactcttag agagtttgtc tactttgtaa ttgtttgact ttttagttac
    51121 atctataact ttttctacat ctaagtcacc aacaacaaat aaagccatat ttcctggatt
    51181 atagaaagta ttataacatt tatatagctc ttccttagtt atcttatata tactatcaac
    51241 agtacctgct atatcaattc tagcaggata atttacatac attgccttca agcaattaaa
    51301 gtatacattc caatcagggt catcattgta catttttatc tcttgtgcta ttataccttt
    51361 ttccttttca acattttcat ctgtaaaata aggtgtttga acatagtcaa ttagatgttc
    51421 taaactctca taaaaatttt cagtagcaga aaataagtag gctgtcattg taaaattagt
    51481 aaatgcattt gcatttactc ctaattttga aaatttatca aatgcatctc ctccatcagg
    51541 ttgctcaaac atcttatgct ctagaaaatg tgcaatacct tcattcactc taattttctt
    51601 atcttctcca attggtacaa attctaagtc atttgaacca taattagtag ccaaaatagc
    51661 atactttttc ataaaacccc ttttaggcat aaaatataca tctaatccat tttgcaattt
    51721 ctcataataa acttcttctt tcaatatatc attaactatt ttttccatag acatctcctc
    51781 cattaatttc tcaagaagta tacagtatca agctctatat tttttatagc ttcaactata
    51841 tctttttttg taaccttttc tatactagat attatgtctt gtacttcaga atttgtcttt
    51901 gccatagact gagagaaaac aaaatcagac ataccaccta tattatcagt tatagatttc
    51961 atagaattaa ctaaagcaag tttactgttt tctaattctt catcagatat atcacctgct
    52021 tttacacttt ctacttgttt ttttatcaat tctacagctt tatcataatc tttagtttct
    52081 ataccagatg atataaacat gatactttta tacttctcta ttgaagagaa tatatagtaa
    52141 cataaacttt ctttttctct tacattaaca aataatttag agtgtggacc accacctaag
    52201 acattgctcc caactactaa agcataatat ttatctatgt ctgcataatc cacatttgct
    52261 ctataaccca taactaactt accttgagtt atttccattt gttcatctat aacttttacc
    52321 tcatccacat tttttataaa atctgctctt ggtatattta taatttcttc tctttcaaat
    52381 tttagatttt tacttattat atctacaact ttatcttcat caaaattacc ttctacaact
    52441 atatctatag gtgatgtttt aagtatgttt ttataatgtt catataactc tcttgaagtt
    52501 atactatcta tttcatcttc ataaccaaat tcacttacac tatatctctc tcctttacac
    52561 atagcctcaa tacatttatc ttgcgcatat tcctttttat catttattat tgattgtatc
    52621 ttttctctta aattctcttt ttcaatattt aaatattctt ctttaaaccc accatctaca
    52681 acaagcgtat tatttattac ttcattaaaa aattctacta cttcttcaaa tatactctca
    52741 tctaaatact tttcacttat gttaattact ttaaaactca atacttgacg ttctccacgt
    52801 tttacagcat cagctcccat agatgaacca tataaatcat ctaatttatt ggatattgct
    52861 ctagcactag gatatttagc gcttccactt gctattattg atggtattag agcatttttt
    52921 gtagtttctt tttcatccaa tagtctctga acatataaac ttataagatt cgatttaaac
    52981 ttttctgttt ttatcaaagt aagattaata ttattaccta aatttattat ttttttagta
    53041 ttaaccatat gtacctccta tttttattta aacatcaatt ttaaaattga aatttattta
    53101 ttttttaatt atatatactc acatataaaa accttctatt taattatatc ctttttatta
    53161 ttttctaaaa gcaatatttt tatttaaatt aaatgcaaat attatttaaa tcaatatgct
    53221 ttaaagtcta gtttacaagc ttgatatata tgatgtataa tcaatatgta tgtctataat
    53281 taaaacaatt ttgcaatcct atagattgat tgtttaaagt tatataaaga atataaaaaa
    53341 gaataagaga gaggacgatt aatatgaaat taggtatagt tggtttgcca aatgtaggta
    53401 aaagcacact atttaacgca ataactcaag caggtgcaga atctgcaaat tacccttttt
    53461 gtacaataga cccaaatgtg ggagttgtat ctgttccaga tgaaagatta aacaaactac
    53521 aagaattata taattctgaa aaaatagttc ctactgctat agaattttgt gatatagcag
    53581 gtttagttag aggtgcttct aaaggagaag gtttaggaaa taaattctta tcacatataa
    53641 gagaagttga tgcaatagtt catgttgtta gatgttttga ggatgaaaat gttgtacatg
    53701 tagatggctc tgtagaccca cttcgcgata tagaaactat aaacttagaa ttaattttct
    53761 cagatataga gattcttgaa agaagaatta ataaaactca aaaagctgct aaggctgata
    53821 aaactttagg ttctgaactt gatttattaa aatcaataat gtctacttta gaagaaagta
    53881 agtgtgtaag aactatggaa tttacagaag atgaacaaac attcgtaaat tcattggatt
    53941 tacttacatc taagcctgta atatatgctt caaatgtatc agaagatgat ttagctgata
    54001 atggagaaaa taataaatat gttcaacaag ttaaagcatt tgcagaaaca gaagatgccg
    54061 aagttgttgt agtatgtgca caaatagaag cagaaatttc tgaacttgat tctgctgaag
    54121 aaaagaaaga gtttttagaa acattaggtc ttgaacaatc agggcttgat aagcttataa
    54181 aatcttctta tgctttactt ggtttaattt cattcttaac tgctggtcca aaagaagtta
    54241 gagcatggac tataaaagtt ggaagtaaag ctcctcaggc aggaggaaaa atacattctg
    54301 atatagaaag aggatttatc agagcagaaa caatagcctt taatgatttg gttgagcatg
    54361 gtactatggc tgctgctaaa gaaaaagggt tggttaaatt agaaggtaaa gaatacatag
    54421 ttaaagatgg agatgtaata ttatttagat ttaatgttta aaatgattaa tcatatacac
    54481 tttgactatt atatataata actaaaaaac taagattata ataatacaat attatcttat
    54541 aataattata tagaatttaa aaataaaaga agagtat
//
LOCUS       DAMJYN010000016        53296 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.016, whole genome shotgun sequence.
ACCESSION   DAMJYN010000016 DAMJYN010000000
VERSION     DAMJYN010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 53296)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53296)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53296
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.016"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(<1..153)
                     /locus_tag="PC466_001079"
     CDS             complement(<1..153)
                     /locus_tag="PC466_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004631111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2768474.1"
                     /translation="MKNRLEEIRKERGIKQEELASILQVSRQTIGSLENGRYNPSIIL
                     AFKIARY"
     gene            complement(327..1193)
                     /locus_tag="PC466_001080"
     CDS             complement(327..1193)
                     /locus_tag="PC466_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDF2768475.1"
                     /translation="MEWINKLNQAITYIEENLESGVDYAEAAKIACCSTFHFQRMFSY
                     IAEVPLSEYIRRRRMTKAAFELQNSNIKILELSEKYGYDSPTSFNRAFQNIHNISPSA
                     ARAKGVVLKAYPKMTLSIYVKGNVEMQYRIVEKKGFRIVGIKESMNMIVEECFEKVPK
                     LWAKCIKNGTIDKLSELINNEPCGLLGVSVCTNSKGLDYYIAAPTDKPVLEDTREYLI
                     PSGTWAVFECVSPMPNALAIQELQKRIITEWLPSSGYVYANLPDIELYPNGDINAPDY
                     TTEVWIPIQKPS"
     gene            complement(1419..2288)
                     /locus_tag="PC466_001081"
     CDS             complement(1419..2288)
                     /locus_tag="PC466_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDF2768476.1"
                     /translation="MDYKTIILNRKSVREYKNIDIKEEYLSEIKKYSESCKKLVPEID
                     VDVRIMNKSEVFNNLDKVAGYKGNMIDSPSYIIILSDIKDNYIENSGYIGESIIFKVT
                     ELGIGSCWVTFEDGKKVKEKLGINSDKEVTGIIAIGYGENVSNAKVLNATKTGQNYSK
                     SDMQVVTDKGSTRLGVEDVVYMNEWGNVASIEILEERALLDAFHYARLAPSTLNRQPW
                     RFIVDGGTVVLAVRKDGHTNLYEEKIDIGIVMLYFATIISATMFDLKWNLGTPDKDYK
                     VPEDYKIVGYCNI"
     gene            complement(2794..3015)
                     /locus_tag="PC466_001082"
     CDS             complement(2794..3015)
                     /locus_tag="PC466_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768477.1"
                     /translation="MNVNNHKCPECGEHSKKFEIVEENEDCVIFECYTCGTISILKYC
                     ENCKEFVFVNIPNNVETYEYCCGKCNNKI"
     gene            complement(3516..4496)
                     /locus_tag="PC466_001083"
     CDS             complement(3516..4496)
                     /locus_tag="PC466_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768478.1"
                     /translation="MGDTSRFYESVKNKYPKLKDGTRVHLWPKENIIIGPIYDEEDGY
                     KKSIGNVDSLSWKQIVILAECDGKNTTDDIINILSNRYRNIHNMKEKVMEFFMFYENV
                     YLTFEDDIQTLSSVFEITGNKSYITPLYFTIEIDGDNNTNDYFSEITSLLNCMYEKGC
                     RFIEVIGEDILKNKSMREIFQYMLDHFDLIVVTKDSFTIDRSLIKELDNYRHKVIWKV
                     YSKNDDTRIKLKEDIKITSLIKRGHTVVRGDREKAIKIEDMRFKDTKERFSKYGAEWS
                     HLYISSDGSVKSYSFQKDKRVYLGNIFNNSVEEIFLEMQNKIDKLEIVYQ"
     gene            complement(4660..5532)
                     /locus_tag="PC466_001084"
     CDS             complement(4660..5532)
                     /locus_tag="PC466_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HDF2768479.1"
                     /translation="MIIKVSMTVLVLILLYILYKYETQHIETTEYTIFNKKIPKEFDN
                     FKIVQVSDLHNKVFDKNNKVLIDKIESLNPDVIFITGDLVDGENKNFQVALDLIDNLV
                     EKYEVYHIIGNHEQKSLIKKYKHLYKDYFKELYSKKIINMENESVRIYRGNSHLNLYG
                     LIIPLECYPYLFANNKKLELSDNFVEDNLGKVNENEYNILLAHTPFFFEKYAKWGADL
                     VLAGHVHGGIIRIPFVGGVLSPNREFFPKYDWGKYEKDNSTMILNKGLGGSKVLIRLN
                     CKPEIVKITLKYEK"
     gene            complement(5696..6247)
                     /locus_tag="PC466_001085"
     CDS             complement(5696..6247)
                     /locus_tag="PC466_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2768480.1"
                     /translation="MDNKFPNVGENLRLLRQEMGISLDKASKMTGVSKAMLGQIERGE
                     SSPTVSTLWKISSGFKINFTTLLNENTNTYEVIKKEEVEPIVEQKGNMKLYPIYPFSP
                     QRRFELFIIELEENCTHVSSTHSYVLEEYVLVIEGKLDLNVDGKTYILESGHSIRFDG
                     TLEHIYKNLNKGKTIFHNIEVYR"
     gene            complement(6267..7169)
                     /locus_tag="PC466_001086"
     CDS             complement(6267..7169)
                     /locus_tag="PC466_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HDF2768481.1"
                     /translation="MSKKGRVVKVQHFSVNDGDGIRTTIFLEGCKLKCKWCSNPDSWS
                     NIVKLGVMKDKCVSCNRCIDVCPQNISSLFDRTQINNKCDLCGECIKVCLKDAICIMT
                     EKMSVEEIVEEVEKDFIFFFESNGGITFSGGEPTLQIDFLRELVDIFYDKGINIAIET
                     CGYFDWNKVNDVFEKIDHIFVDIKSMDDNIHKEYTGVSNKIILDNICRLSKLNKSMVI
                     RVPIIYGVNDSEENIRNTALFVKQNVPGGKMELLPYHKFGIDKYKALGLEDYIYEFDE
                     ICNNHMLKLKEIVELTGVKIIEYK"
     gene            complement(7184..9556)
                     /locus_tag="PC466_001087"
     CDS             complement(7184..9556)
                     /locus_tag="PC466_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase/glycerol dehydratase
                     family glycyl radical enzyme"
                     /protein_id="HDF2768482.1"
                     /translation="MSQTNRIEAFRQEYINSKPMICCERARIFTESHKKTEGEAICIR
                     RAKAFLETCKELPIKIFENELIVGTAGKFRRTGILTPEFSWQWVDKEMDTFDKRTQDP
                     YVISKEQIEFIRKEIFPYWKGKSLEEVFLARIPEDTAKILVDTGIIDNDSKWRQAVGE
                     VTPDYQDILFVKGYKGIKEDADKKIKELDISVSENIEKIDFYKSVSIVAEGIMTLAQR
                     YSNLAKEMSKQETDEKRKLELIKISEICMNVPANPPTNFYEAIQFVWFVQLGGILSEN
                     PLALNLGRFDQYMYPYYENDAREGKITESEAQELIEALWIKLSEWVWTISANTANYFA
                     GYNQFQNLTVGGKKRNGTDGTNDISYMCLKATESVKTHQPGLSVRVSQGAPDNFVMAV
                     AKLVKQGTGFPAIHSDSAGAQMLLQDGYDAEDARDWSNCGCVVPHFRKTGQWTSAVNI
                     NFAAALEYAMNEGKSRLTGEKMGLDTKNITEFTSFEELKDEFLKQLAYLVKSSVIGTT
                     VAQQIHKEMVPRPFLSTCVDGCLDKGVDLSKGGAKYNIGPVLTGIGLGVVSNSLAAIK
                     KLVFEDKVTTLEELTKALNNDWEGYEELRKLALDVPKYGNDNDYVDSLAIEVSDFYYT
                     ETRKYKDIFGSKFNSAFMGISNYVPTGKIVGATPCGRKATKPLTEGVSPFVGTDTTSP
                     LAAMKSASKINHDVHTGGTLLNLRLNQDLVETERGLRNLTSMIKSYFALGGFHVQFNT
                     ISNDTLLKAQENPEEYKDLLVRVAGYSTQFVNLSREMQDAIIARNSHSNF"
     gene            complement(9775..10464)
                     /locus_tag="PC466_001088"
     CDS             complement(9775..10464)
                     /locus_tag="PC466_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768483.1"
                     /translation="MKVKRNINRVAIIVALNLSLALMAGCMSPVSDKNLSSSEQISKD
                     SLKEQVEDKKDESIELFNNYSQKINDAKGREEVKKDLSQRFSKAIIDSGYSITDSKSD
                     GSFVVSINGAEKPPEKNIRSLFYSMSEDDKEGKVTIDILCAKEYPEDDKLSESDKYIK
                     FIYNLFKSLTNTNLTEKEIFSMVEEEFNKGVGVVELPYMKDIHVEVNKVKQSTKVLKL
                     SLVYKFDISNH"
     gene            complement(10705..12084)
                     /locus_tag="PC466_001089"
     CDS             complement(10705..12084)
                     /locus_tag="PC466_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HDF2768484.1"
                     /translation="MLNFMNELLVVLSIFIQFSIMNGILIYKKDSKKNEKIVFYIVLF
                     LIYIIIQISRLFNGGSYFSNINYLFYILAFIAWGGYYNYFYKMDYIKYSIFFYLFSVY
                     YKCLDAVIYRILFFAITGNVISSKESLLVPHLESIKIQIYSNLIIILIYLVFSFFRKS
                     IKLISQDKRNYVYLLFALLANTMNMLVNYVLKKLERFGSLHSEGYYFDNFVNPKLVGA
                     SSIFLILLFKEIIKENRLKSQAELIKNKLDMQYAHYLSIQESHMRVKKLYHDINNHIY
                     CIDNLRNNSKEINEYVNNLKDEIKTFKYIYNTGNMILDIIINEKSEICLKKGIKFTCS
                     INFSKVNFVKPIDVSSIFSNILDNAIEACDKIVDENINKYIRIKGTITKSFFVLKCEN
                     SKLNQLTFNKNILLTNKMDKFVHGIGIQSIKSSLQKYNGELLFENSIDKFILNIYIPL
                     EQDTDSWGD"
     gene            complement(12078..12791)
                     /gene="rgbR"
                     /locus_tag="PC466_001090"
     CDS             complement(12078..12791)
                     /gene="rgbR"
                     /locus_tag="PC466_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RgbR"
                     /protein_id="HDF2768485.1"
                     /translation="MIKIAVCEDEKETQLLIEDYLENILKDISIEYEIQKYISGEELL
                     ESNLKDIDILLLDIKMEKLNGMDTARKIREVDDEMEIIFVTSLIDYVQEGYEVRAYRY
                     LLKPIELEELKKHVLTCIKDIEINKESHITIKNKSNTYKIYLNEIKYIEVQKKDMLIH
                     TINKNFDIKYSLGKIEKELNPYKFIRCHKSFIVNLRYVENIKPNAAILESGEEVPISR
                     YRYKEVKEKFLKFLGDTIC"
     gene            complement(13042..13602)
                     /locus_tag="PC466_001091"
     CDS             complement(13042..13602)
                     /locus_tag="PC466_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HDF2768486.1"
                     /translation="MSAMEKKIKFKFDWYSSPDKIEKWLEDIEAKGYNLYKINKFGGI
                     FYFHKGSPRKIKYTVDYYYDVENNYFDEHKSNGWNLVFRSIGSFMGTSAWYIWSKEYK
                     DIPPKLYSDSDKKNKVKSILFMNMFIFFMLVVIFIYLLNIEIRNLYSGYGASVTAIVL
                     QIILLILYAVQLYRRLMYYLRLKKFK"
     gene            complement(13698..14501)
                     /gene="zupT"
                     /locus_tag="PC466_001092"
     CDS             complement(13698..14501)
                     /gene="zupT"
                     /locus_tag="PC466_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc transporter ZupT"
                     /protein_id="HDF2768487.1"
                     /translation="MNNVIFAFLITLLAGLSTGIGSCIAFFAKKTNTKFLSISLGFSA
                     GVMIYVSMIEIFPKAQDALTKSMGEKLGSWSTVIAFFIGMAIIAVIDKLIPQEENPHE
                     IKKMENIEEKNIKKNKSLLRTGIFTAMAIAIHNFPEGLATFISALDDVTIAIPIAIAI
                     AIHNIPEGISVSVPVYYATGDKKKAFYYSFLSGMSEPLGAIIGYVLLRNFLNDITLGI
                     VFAIVGGIMVFISLDELLPSAREYGEHHLSIYGLIAGMGVMAISLLLFK"
     gene            complement(14652..15815)
                     /locus_tag="PC466_001093"
     CDS             complement(14652..15815)
                     /locus_tag="PC466_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2768488.1"
                     /translation="MDIKEITKSYKDYVIKLRREFHENPEKSMEEVRTSKRVKEELDK
                     IEIPYVSAGGTGVIATIKGANPGKTVALRGDMDALQVVECTDVEYKSKNEGLMHACGH
                     DGHTSMLLGAAKVLNDIKDSINGTVKLFFQPGEEVGKGARAMIQDGAMEGVDSVFGIH
                     LWTDVESGTISVEEGPRMASADFFKITVKGRGGHGSLPHQGVDAVLASSAIVMNLQSM
                     VSREVSPLEPLVVSVGVLNSGTRFNVIASEAVLEGTIRLFNPELRKQIPGILERIAKS
                     TAEAYRADAELEYGYLTPAVINDKECSKIATDAAIKLFGEDCITLFEKVTGAEDLAEF
                     MNIAPGALAFVGARNESKGACYPHHHGCFNIDEDALEIGTALYVQYAVDFLNK"
     gene            complement(15875..17062)
                     /locus_tag="PC466_001094"
     CDS             complement(15875..17062)
                     /locus_tag="PC466_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768489.1"
                     /translation="MEAITAFCLVLISLTIGDIVSAKTKAFVPSVFVSAIIFIVGFWT
                     FFPENIVDLAALGTPLAQLGMLLLITHMGTMMSIKELAGQWKTIVIALAGIVGICVGA
                     LALGTIVFGWDTAVIATPPLTGGLVASIMMADAATAKGLASLSVLAILMYVAQGFAGY
                     PITALMLKKEGKRLLSDFRSGKVTVNTDEEKVKDLPEQKSRFKIIPDLPEKYDTTYMI
                     ILRLGFVAWLAVQFTNLTNEVVSRYVICLIFGVIASELGIVDRKPLNKSGSFGWLMTS
                     LMAFIFAGLAKATPAMLVEMAVPLVGIIIFGVIGMGIFSIIVGKLLGESKEMAFSVSL
                     TSLYGFPPNYILTEEAVKALAETPEEKEFLMDKMLPKMLVGGFTTVTIASVVIAGIFV
                     NLI"
     gene            complement(17425..19125)
                     /locus_tag="PC466_001095"
     CDS             complement(17425..19125)
                     /locus_tag="PC466_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2768490.1"
                     /translation="MIKQFVKYYKPYKKIFTLDLIAAFLFSLCDLVYPMITRNIMDDV
                     VPNKNLRMLVVFAVALILIFIAKAGLNYFMQYWGHVIGVDMQADMRNEVFTHLQRLPN
                     TYFDNNKSGVTMSRIVNDLMDITELAHHGPEDLFISIVMLVGSFFILIDINIPLTLII
                     FAILPFIIWFAIAKKDKMNIAFMKSRVTIGDVNATLENSIAGMKVTKSFCTEKEELNK
                     FVRSNKLFRRARQDSYKVMAEYYSGMNLYMDILEWVVVIAGGYFTYIGKITLGDFAAY
                     ILYVKMFIQPMKKLINFTEQYQNGMTGFKRFIEIMEQDHQKEAKNPIELENVKGDIEI
                     ENISFTYEDKTQVLDNLSLSIKAGKTIALVGPSGGGKTTLCNLLPRFYEFDKGDIKID
                     GKSIKDVSLKSLRKNIGIVQQDVFLFTGTIRDNILCGNPNATDEEMIAAAKKARIHDF
                     VETLPDGYDTYIGERGVKLSGGQKQRISISRIFLKNPPIIILDEATSALDNVTEREIQ
                     ESLEELSKDRTNLVVAHRLTTIKNADEIIVLTDKGIEERGTHEELVNKNGVYSRLHNN
                     "
     gene            complement(19381..19656)
                     /locus_tag="PC466_001096"
     CDS             complement(19381..19656)
                     /locus_tag="PC466_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2768491.1"
                     /translation="MKKILVACGAGIATSTIVCDRVERLVKENNIHAEVEQCKIAECS
                     TKQEGADLIVSTTILPTTYDIPTIKATGYITGINTTALDKKILNALK"
     gene            complement(19775..20326)
                     /gene="mobB"
                     /locus_tag="PC466_001097"
     CDS             complement(19775..20326)
                     /gene="mobB"
                     /locus_tag="PC466_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-guanine dinucleotide biosynthesis
                     protein B"
                     /protein_id="HDF2768492.1"
                     /translation="MKGHNFMYNILSVVSYSGVGKTTLIEGIIKELNKKGYRVGVIKH
                     TCHDFDMDEEGKDTYKHRKSGARKVCIISDKRVAYIEELKEKNPLYKMIQLYEDMDLI
                     IIEGYKNYRFKRLEVTRKGKYEDILSNKSDLIGIVSDIEYKLNIEQFNLNDYKNISKY
                     IESCIKNEILSISNVEIKNILKE"
     gene            complement(20331..21512)
                     /locus_tag="PC466_001098"
     CDS             complement(20331..21512)
                     /locus_tag="PC466_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin molybdotransferase MoeA"
                     /protein_id="HDF2768493.1"
                     /translation="MIELEDAIKIIEKNVLPINRVKIVNLIDAVNKVVAEDIYSTIDS
                     PPFDRSPYDGYAYNANSENRNLKVIGTLYAGEVFNKVLNKNEAVKIMTGGKIPQGANC
                     VIKKEDVTVIGDMIILNVKLKEYDNYIFKGEDIKKGQLIINKNQNIGYDGIGVLASLG
                     ISKVTVYDDLKVGILNTGTELQDINETLENGKIYDSNRYTLYSRLLKLGIQADTICNC
                     SDDILELEKKVKNMLQSVDFLITTGGVSVGDKDLIPDVFKKIGATELFWKINIKPGGA
                     CYVGILGEKLLFGLSGNPHAAIVVFDNVIVPVIEYLTYKKGIHHIKAIFKGEFNKLSN
                     KDRFVSGKLYTSEGKLYVELNDKKDAKARLSATLRSNCMIKIKKNETIKENQLVEIVI
                     R"
     gene            complement(21723..22457)
                     /locus_tag="PC466_001099"
     CDS             complement(21723..22457)
                     /locus_tag="PC466_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768494.1"
                     /translation="MKLKRSLVCVTILGIILVGCHKENTKEKNQVASKATQQKTMTKV
                     QNDVNEIMNKDYKYIIKNMGIPYNTFYYIKPKVLKESNTMQDINTSSYMTLVYPKYTG
                     NDELDGSALYVDINENKVVNVETNSFSSQGISVIDAESSVVIEKSDHEKSAVSLENFR
                     RIDLGEYVGVEESRINEIVGDANYDLTAYNHEGSKVVKSYRLKEDNKILKKEVLTISI
                     VDNKIKSIKTIESDKIVKIIKGTLLE"
     gene            22819..23724
                     /locus_tag="PC466_001100"
     CDS             22819..23724
                     /locus_tag="PC466_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDF2768495.1"
                     /translation="MDFKQLEVFVAVAKHQSFSKAARELFLTQPTVSAHIQNLERELE
                     TVLINRSNKVITLTKSGEILYEHAIYILNNCKRAIYDIKEYSGKIEGIIDIACSSIPE
                     TYILPDFMKSFSMSYPDVKFSISHYDSQYAISEILNERISFGLVGSKINNPQIEYLDL
                     LDDELVLITPSDFKIDNKNNCIDIGELAYLNFIMRKEGSGTRNLILNTLSKNNFPVSK
                     LNVIAHVESNEAIKEMVRLGLGVSFISYISAIDYLNAGKIKCYKIKGVDFTRKFFFIY
                     SKKKTFSPLEDKFLNRLCEYFEIII"
     gene            complement(23884..24726)
                     /locus_tag="PC466_001101"
     CDS             complement(23884..24726)
                     /locus_tag="PC466_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HDF2768496.1"
                     /translation="MTTSSKKLDTISPDSKITRKDFWKCFRRSLTLDSSWNYERMQNI
                     AYAYMMAPIIRRLYKDDKEKKSKALKRHLEFMSVTPHISTLLVGISGAMEEENAKNKE
                     FDANSINAVKSSLMGPVSGIGDSFFWGTLKLIAAGVGIALASQGNIMGPILFLLIINV
                     PHFIIRYICLDKGFKYGTQFFKDVSSSSIVSKVMEAASMLGLMVIGGMTASNVMLKLS
                     VNVGSGEWAEPIQTYLDQIMPCMLPAMIFGIMYWLLGKKVKTTTILISVMIICIVLAA
                     IGIV"
     gene            complement(24710..25468)
                     /locus_tag="PC466_001102"
     CDS             complement(24710..25468)
                     /locus_tag="PC466_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF2768497.1"
                     /translation="MEFTQVILITLIAFFAYMHSFVGSTMHNRPIVVAPLVGLALGNL
                     HTGIVIGSTLELVFMGAFPVGASNPPDFVSGSIIATAFVILTGQDVSAAVVLAVPIAT
                     LVLLIDNFLMTVVLTWGAHIADRYAEEGNIEGVERVQLLFGIGNKLILAIIVGIGFSL
                     GVPVIEKILSFIPSYVTHGMDVAAGVIPAIGFAMLARMMLNKKTVAFLLLGFILVAYL
                     NITVTGVALFGLAIALIYVNFVGEKEVIVDDNEF"
     gene            complement(25485..25955)
                     /locus_tag="PC466_001103"
     CDS             complement(25485..25955)
                     /locus_tag="PC466_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2768498.1"
                     /translation="MIKLVRVDHRLIHGQVAFTWTKFLSTDCILIASDELLKDELRMA
                     GLKMAKPSNVKLVMKSIADSIKALNSGVTDKYNLLILCESVEDVYRLAKEVKAIKSIN
                     LGGTKSDDNRENISKAVHVSKDDIKMIKELDSEGVNVFVQLVPDDDATNVMKLI"
     gene            complement(25955..26698)
                     /locus_tag="PC466_001104"
     CDS             complement(25955..26698)
                     /locus_tag="PC466_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane biogenesis protein"
                     /protein_id="HDF2768499.1"
                     /translation="MKKKGILSVFKSKKPIIAMIHLKGDTPEDIFERAKKEITIFEEN
                     GVDGIMLENYYGNYYDLERILEYVSKANLSIPYGVNCLNVDTMGFELATKYNASYIQV
                     DSVVGHVKPRDEATLEEFFKLQRSKCPAYLIGGVRFKYQPVLSENDVEEDLKIGMTRC
                     DAIAVTENATGQETSMEKIELFRKNLGDFPLVIAAGVTLENAKKQLELGDMAIIGSYF
                     KDNYKDFGNVSVEHVKTFMDEIKKIREEL"
     gene            complement(26702..27115)
                     /locus_tag="PC466_001105"
     CDS             complement(26702..27115)
                     /locus_tag="PC466_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIC"
                     /protein_id="HDF2768500.1"
                     /translation="MKKIILASHGDFSKGLLNAVKMIVGDLADCVSSYGLYPGQSASD
                     FALELEKTISEDIECEYIILSDLYGASVCTAMLRLTNLHNVKLFSGMNLNMVLELLTR
                     FSDELTVEDIEQLVEESRRGIQSVTLQIKEEEEVF"
     gene            complement(27141..27893)
                     /locus_tag="PC466_001106"
     CDS             complement(27141..27893)
                     /locus_tag="PC466_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2768501.1"
                     /translation="MDEKRQKKEMDLEVNSFVPLYQQLYDNIKKQIASGIYKPGDKLP
                     SEGDLCKEFNISRITVRNALNELVKEDILCKKRGKGTYVTIPERIEATCAGNSFTNSC
                     HRINAKPSTKIISVLIKKADKQVAEALSIELEEKVICIKRLRLIDEVPVIFEVDYFRI
                     DYMFLLKEELEDKSLMEVISNNISTLPKRVENIFEVKHSNKEYSDYLKCASNMPLLKV
                     RQSVYTENNDVLYYNEQFIRSDKYKYAVSAEI"
     gene            complement(28133..29527)
                     /locus_tag="PC466_001107"
     CDS             complement(28133..29527)
                     /locus_tag="PC466_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HDF2768502.1"
                     /translation="MNLKYEFKNAWDFERKENTIEQIMQYSRNYMEFLSKSKTERLSV
                     KEIIKLAKENNYISIDEAMEKGSISCGDKIYVINKEKAVALFVIGKNYIEKGMKIIGS
                     HIDSPRLDLKPNPLYQESNLGFFKTHYYGGIKKYQWTALPLALHGIVILNDGTKVDIS
                     IGEEDSDPVFCVTDLLIHLAGDQMQKKLSEGISGEALNILIGNIPLEDEEKEPITANI
                     LKILNEKYNIVEEDLLSAEIEVVPAGKARDLGFDRSMVLGYGHDDRVCSYAAVKAILE
                     TEQPEFTSVALCVDKEEIGSKGNTGMHSKFFENTVAELIALEGDYCDIKVRRALANSK
                     VLSADVSAGYDPNFGEAYEKRNSAYMGNGVVLTKYTGSRGKSGCNDANAEFMSEVKRI
                     FNKGNVVWQTAELGKVDQGGGGTIAHILANQGAEVIDCGVGVLNMHAPHEIVSKVDIY
                     EMYKGYKAFFNINL"
     gene            complement(29547..29756)
                     /locus_tag="PC466_001108"
     CDS             complement(29547..29756)
                     /locus_tag="PC466_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 domain-containing protein"
                     /protein_id="HDF2768503.1"
                     /translation="MFDKKKLDRINELAKKNKEGILSADEIKEREILRKEYLENFRAH
                     FRSRLDSVKVVSPEEYEQYMKNNKN"
     gene            complement(29785..31230)
                     /locus_tag="PC466_001109"
     CDS             complement(29785..31230)
                     /locus_tag="PC466_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HDF2768504.1"
                     /translation="MEKYRIDLNEKKSTKYIQIFNHIKELIINKELVEHEKLPPIRKL
                     SNFLQVNNTTIVKVYELLENEGYVYKIIGSGTFVSSSNSYKSGIDNRKNKIIVQREDL
                     IHFDNGNPSNDMFPIDSFKNAVNMALSKDGSSIFEYDEGLGSEELREKMVEYLSDGNI
                     KTTKENIQIISGAQQGIDIVCKGLISYSDVVFMEEPSYNGAIEVFKSRGAKIISIPML
                     DDGIDIGILKLKLEKIKPRLIYIMPNFQNPTGISYSTYKKKKLIELAEEHDFYIIEDD
                     FISDFVFESKDNRTIRSYDDKNRVVYIKSFSKILMPGLRIGIVEMPNELLKKVLWAKY
                     SSDISTPGLIQKSMYYYMNNFDWKNYLSHIEKIYTNKYKLSKNLINDKLSGKLKVRKS
                     CGGINFFLELPRGYTSQAFTNFMLNKGVSMLPGTYFFDNLVDDRFFRINIARPSMEEL
                     EKGISVISDNIDEFFCEYKNKLDIKSNKLFY"
     gene            31340..32134
                     /locus_tag="PC466_001110"
     CDS             31340..32134
                     /locus_tag="PC466_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase HisJ family protein"
                     /protein_id="HDF2768505.1"
                     /translation="MFYDYHMHSSFSTDGKSTMEEMVKKSIELGLEEICFTDHVDYDV
                     YADDSFSIVYEDYFKSLETLQSKYKDKISIKKGIEFGVQTQLMDTYKKEAHQYPLDFI
                     ICSIHAIDTMDLYLGNYFKDKTQYEVYENYYLYLYNIVKNYKDYSVLGHLDLIKRYAP
                     YDTILDDRLFSDIIEETLKQAIYDGKGIEINTSCYRYNLPDLTPSKYILQMYKDLGGE
                     IITTGSDSHHISQVACEFDYIYSLLKNMGFKYVSKFNKLKPEFIKL"
     gene            32185..33507
                     /locus_tag="PC466_001111"
     CDS             32185..33507
                     /locus_tag="PC466_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HDF2768506.1"
                     /translation="MKVPYLVLSTVILFISNFIVRIFGFLYKIFLSRALGETGLGIYH
                     MIFNFLMICLAVTTTGIPTALSCLVAKRKALNDRHNTNALFISTLYISFFVALIISIV
                     ASFNSSFLSLKFLKDAKLNLFILAVCPAIVIITLSNVLRGYYYGIKNVKIPAIGQIIE
                     QIGKILFVFLLVMYINNKSMNCYIALLGISIGELSNIIFMLICLWRDSSFDNRYIISI
                     KDFYNSSMETLKMSIPITCNRMSNILLQSISSMMIPSRLALSGMTYQQSLSMYGIVSG
                     MVMPFIFLPFTVGSALIVNLIPTISQEMALRKRKSVIKKIKYSILLTLFVGILSSIFF
                     YFFGKDLCILVFKNTLAGEYLKAMFLVPLFMSLNQTLSGILHSIRKELASSINTITGM
                     LIQLIALYVFLPIPGLNIYAYIYTMTIVSIFTCLLHTIVLFKSLKSIR"
     gene            complement(33608..34825)
                     /gene="cdeC"
                     /locus_tag="PC466_001112"
     CDS             complement(33608..34825)
                     /gene="cdeC"
                     /locus_tag="PC466_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exosporium morphogenetic protein CdeC"
                     /protein_id="HDF2768507.1"
                     /translation="MQDYKKNKRRMMNQPMSTMNEEEVYTDEINSEDMRGFKKSHHHN
                     GCNTDNKCECHDECNPCNPCNPCKPNPCNPCKPNPCDDKCECHDKCKCDCEPCEMDSD
                     ECFENKCGPECCNPISPRNFSVSNAVPFAIEANRIFDTMQFQTFTDATGPNGEPLTFE
                     TEVVEVFGSIPSAGQASVTIEKICLSNDGIVIDTGMTTLEDFDLDPLGDIVGRNCETT
                     FEFAVCGERNAECCRQGKGKSVAYKQRGLTVAVRNLVLELRGRCGCTEFVALAFPAVR
                     AGGGCKRRVDYVEFTFNTLSAPICLPADGRAVTLRQEYQTNLTVDCIGKSILKLECNE
                     CCEPFYELIIPNDIDLVLCLQETVSTLISEQIVVLASPNPIQPRLVDTFSKVCDFSQC
                     GPNHGSGKPSCHR"
     gene            complement(35008..35188)
                     /gene="ssrS"
                     /locus_tag="PC466_001113"
     ncRNA           complement(35008..35188)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="PC466_001113"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(35303..36208)
                     /locus_tag="PC466_001114"
     CDS             complement(35303..36208)
                     /locus_tag="PC466_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768508.1"
                     /translation="MNNLLFLIGVIALSNGNISIFDDKNKSKGNNRVRKNKKNANDKL
                     SQSTHGNLRFDANDIKRGLRLMDLSEEDLEMGMEIITRTKKYMSRDERKILIKIESVL
                     DLVRGIKKLNNIDMVDTEDETDFFRKMDSDDKKNMMIKEIIDVFPEKRKNSVEKAIGM
                     KKKIDLFAELFLPDDFGEGGFSLSSLANINNLGSMNNLKLLGSLLRGDDSNNDDEDNN
                     DELNYEDEELDCEDKELDDDELTDEGEMEDNEDELVEDKNTGYENIENDEDIVYDEEL
                     YNINEQESEYNYNEKNTKTRAKKKR"
     gene            36420..36818
                     /locus_tag="PC466_001115"
     CDS             36420..36818
                     /locus_tag="PC466_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768509.1"
                     /translation="MKKLDTESLEKMAKQKNIDKDKIEKMADSYKGKSENELMEELIK
                     IGKNLDGRDEVVSKFKAFLDENQRKKLDNIMEKISDAENQRDTKPAKTKKAKPTKGKS
                     NSPAPKNTPGGQQKKSKGLFKKTKKSNPHE"
     gene            complement(36941..37957)
                     /gene="ccpA"
                     /locus_tag="PC466_001116"
     CDS             complement(36941..37957)
                     /gene="ccpA"
                     /locus_tag="PC466_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator CcpA"
                     /protein_id="HDF2768510.1"
                     /translation="MKGNITIKDVAKQAGVSISTVSRVINDSKPVTDEVKQKVLEVIK
                     ETGYIPNPLARSLVTKKSQLIGVIVPEVSDSFVNEVLNGIEEVAKMYDYDILLANTYS
                     DKEQELKSINLLRAKQVEGIVMISWIVEQEHINYIQNCGIPATYISKTARNYDIYTVS
                     TSNEEATFDMTEHLIKKGHEKIAFIMTSKDDTVLEMERLAGYEKALSNNNIELDKSLI
                     KYGGTDYESGYNSMKELLDDGIIPHAAFVTGDEAAIGAINAICDAGYKVPEDISVAGF
                     NDVKIARMYRPKLTTVYQPLYDMGAVAIRMVIKLINKELIENKKIELPYRIVDRESVT
                     ERKK"
     gene            complement(38210..38410)
                     /locus_tag="PC466_001117"
     CDS             complement(38210..38410)
                     /locus_tag="PC466_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768511.1"
                     /translation="MLDRFFGEEGCFGGGGWWIIVLFFLFLAFEDCWRDIDIMSWIPF
                     LILLLITCSCGGFFDGEVGCGC"
     gene            complement(38444..38623)
                     /locus_tag="PC466_001118"
     CDS             complement(38444..38623)
                     /locus_tag="PC466_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768512.1"
                     /translation="MLDRFFGEEGCFGGGGWWIIVLFFLFLAFGDSWAEFDIMAWIPF
                     LIVLLILCCCGGCLE"
     gene            complement(38805..39011)
                     /locus_tag="PC466_001119"
     CDS             complement(38805..39011)
                     /locus_tag="PC466_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768513.1"
                     /translation="MTKLEDNMERFFGGCEGFFGNKMLIIIVIVFLLLCTDILEDLLC
                     DDNIWIWVILIVLLLFNFDDGCCC"
     gene            complement(39059..39484)
                     /locus_tag="PC466_001120"
     CDS             complement(39059..39484)
                     /locus_tag="PC466_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768514.1"
                     /translation="MKYVGLLLTSVGMFLLIAVNFYYNSITLDMQRIEDYVMETNLIL
                     EDVAEKESYVSNEKEDYISRLMHVKKGIENSKTSFLIERYKEYKIKSIESLIYTISEE
                     KKDYLDEVDRYNKLGEKEINKLINKNFLEVTYLSITTYI"
     gene            39656..39883
                     /gene="acpP"
                     /locus_tag="PC466_001121"
     CDS             39656..39883
                     /gene="acpP"
                     /locus_tag="PC466_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HDF2768515.1"
                     /translation="MFEKIKEIIAEQLGVDNLDEITMEASLMDDLEADSLDAVEIIMA
                     LEDEFGIEIPDEEAENFKCIGDICKYIEENK"
     gene            complement(40027..41031)
                     /locus_tag="PC466_001122"
     CDS             complement(40027..41031)
                     /locus_tag="PC466_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HDF2768516.1"
                     /translation="MIIHKFIIHVLDKNSDVPILNDFEGKVNQEVDGFFQKAIKRIAK
                     DEDLRKGVFKDYNDNLIKNCCEQIIYDESTFLKNSKEIASYLFDVMKINAALESCDLA
                     ICLYTIKDEKSVAILKLDYKKLYTHSIEFVDDKFNIQMVSNEIGIPETLRQKQGALIS
                     LSGINDEFHLRLLDKDAEKEGSESKFVTEFLNAKKIDDDKYKTKVFKNTAENWITNAL
                     SNDIKQAEDVRSILNYTLKEKHEVDINDFVDNSIKDDELKDSFKEHMEEKGLDESFSI
                     DKKWVEKKLKKRSIKTDNGFDIKGNLTDFEDPMKYTVKQNQDGTIDIIIKNVTFYEEK
                     "
     gene            complement(41045..41947)
                     /locus_tag="PC466_001123"
     CDS             complement(41045..41947)
                     /locus_tag="PC466_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HDF2768517.1"
                     /translation="MFKKENQRYNLISYTNEEEMTLKEVLLDKLNFSVRSLSKMKKEK
                     SVLVNGVYKKPSLKVYSGDLIEVKIDEEKANFEPQDLNLQIIYDDFDIIMVNKPPFMV
                     VHPTKSHYDKTIANGISYYIDNQKENVKIRFVNRLDMNTSGLVIVAKNAYAHHTLSTA
                     MSENKVEKKYITVVDGIIKENEGTIDEPIYRPTEDSIKRIIDERGQSSVTHYKVIERL
                     ENATVLEVSLETGRTHQIRVHMAHIGHGIIGDELYGYVDEELINRQALHAYKLEFEQP
                     RTKEKLKFKADIPEDMKELISKLR"
     gene            complement(42142..43317)
                     /locus_tag="PC466_001124"
     CDS             complement(42142..43317)
                     /locus_tag="PC466_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000786547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HDF2768518.1"
                     /translation="MREVVIASAARTAVGSFGGAFKSVSAVELGVTAAKEAIKRANIT
                     PDMIDESLLGGVLTAGLGQNIARQIALGAGIPVEKPAMTINIVCGSGLRSVSMASQLI
                     ALGDADIMLVGGAENMSMSPYLVPSARYGARMGDAAFVDSMIKDGLSDIFNNYHMGIT
                     AENIAEQWNITREEQDELALASQNKAEKAQAEGKFDEEIVPVVIKGRKGDTVVDKDEY
                     IKPGTTMEKLAKLRPAFKKDGTVTAGNASGINDGAAMLVVMAKEKAEELGIEPLATIV
                     SYGTAGVDPKIMGYGPVPATKKALEAANMTIEDIDLVEANEAFAAQSVAVIRDLNIDM
                     NKVNVNGGAIAIGHPIGCSGARILTTLLYEMKRRDAKTGLATLCIGGGMGTTLIVKR"
     gene            complement(43404..44249)
                     /locus_tag="PC466_001125"
     CDS             complement(43404..44249)
                     /locus_tag="PC466_001125"
                     /EC_number="1.1.1.157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxybutyryl-CoA dehydrogenase"
                     /protein_id="HDF2768519.1"
                     /translation="MKLAVIGSGTMGSGIVQTFASCGHDVCLKSRTQGAIDKCLALLD
                     KNLTKLVTKGKMDEATKAEILSHVSSTTNYEDLKDMDLIIEASVEDMNIKKDVFKLLD
                     ELCKEDTILATNTSSLSITEIASSTKRPDKVIGMHFFNPVPMMKLVEVISGQLTSKVT
                     FDTVFELSKSINKVPVDVSESPGFVVNRILIPMINEAVGIYADGVASKEEIDEAMKLG
                     ANHPMGPLALGDLIGLDVVLAIMNVLYTEFGDTKYRPHPLLAKMVRANQLGRKTKIGF
                     YDYNK"
     gene            complement(44347..45144)
                     /locus_tag="PC466_001126"
     CDS             complement(44347..45144)
                     /locus_tag="PC466_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="HDF2768520.1"
                     /translation="MSTSDVKVYENVAVEVDGNICTVKMNRPKALNAINSKTLEELYE
                     VFVDINNDETIDVVILTGEGKAFVAGADIAYMKDLDAVAAKDFSILGAKAFGEIENSK
                     KVVIAAVNGFALGGGCELAMACDIRIASAKAKFGQPEVTLGITPGYGGTQRLTRLVGM
                     AKAKELIFTGQVIKADEAEKIGLVNRVVEPDILIEEVEKLAKIIAKNAQLAVRYSKEA
                     IQLGAQTDINTGIDIESNLFGLCFSTKDQKEGMSAFVEKREANFIKG"
     gene            complement(45163..46173)
                     /locus_tag="PC466_001127"
     CDS             complement(45163..46173)
                     /locus_tag="PC466_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HDF2768521.1"
                     /translation="MGNVLVVIEQRENVIQTVSLELLGKATEIAKDYDTKVSALLLGS
                     KVEGLIDTLAHYGADEVIVVDDEALAVYTTEPYTKAAYEAIKAADPIVVLFGATSIGR
                     DLAPRVSARIHTGLTADCTGLAVAEDTKLLLMTRPAFGGNIMATIVCKDFRPQMSTVR
                     PGVMKKNEPDETKEAVINRFKVEFNDADKLVQVVQVIKEAKKQVKIEDAKILVSAGRG
                     MGGKENLDILYELAEIIGGEVSGSRATIDAGWLDKARQVGQTGKTVRPDLYIACGISG
                     AIQHIAGMEDAEFIVAINKNPEAPIFKYADVGIVGDVHKVLPELISQLSVAKEKGEVL
                     AN"
     gene            complement(46192..46974)
                     /locus_tag="PC466_001128"
     CDS             complement(46192..46974)
                     /locus_tag="PC466_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009524639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HDF2768522.1"
                     /translation="MNIVVCIKQVPDTTEVKLDPNTGTLIRDGVPSIINPDDKAGLEE
                     AIKLKEEMGAHVTVITMGPPQADMALKEALAMGADRGILLTDRAFAGADTWATSSALA
                     GALKNIDFDIIIAGRQAIDGDTAQVGPQIAEHLNLPSITYAEEIKTEGEYVLVKRQFE
                     DCCHDLKVKMPCLITTLKDMNTPRYMKVGRIYDAFENDVVETWTVKDIEVDPSNLGLK
                     GSPTSVFKSFTKSVKPAGTIYNEDAKTSAGIIIDKLKEKYII"
     gene            complement(47033..48169)
                     /locus_tag="PC466_001129"
     CDS             complement(47033..48169)
                     /locus_tag="PC466_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="HDF2768523.1"
                     /translation="MDLNSKKYQMLKELYVSFAENEVKPLATELDEEERFPYETVEKM
                     AKAGMMGIPYPKEYGGEGGDTVGYIMAVEELSRVCGTTGVILSAHTSLGSWPIYQYGN
                     EEQKQKFLKPLASGDKLGAFGLTEPNAGTDASGQQTTAVLDGDEYILNGSKIFITNAI
                     AGDIYVVMAMTDKSKGNKGISAFIVEKGTPGFSFGVKEKKMGIRGSATSELIFEDCRI
                     PKENLLGKEGQGFKIAMSTLDGGRIGIAAQALGLAQGALDETVKYVKERVQFGRPLSK
                     FQNTQFQLADMEVKVQAARHLVYQAAINKDLGKPYGVEAAMAKLFAAETAMEVTTKAV
                     QLHGGYGYTRDYPVERMMRDAKITEIYEGTSEVQRMVISGKLLK"
     gene            complement(48877..49344)
                     /locus_tag="PC466_001130"
     CDS             complement(48877..49344)
                     /locus_tag="PC466_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaK/EbsC family protein"
                     /protein_id="HDF2768524.1"
                     /translation="MSISNVREYFKQFGKEDSILEFEQSSATVELAAEAAGVIPARIA
                     KTLSFKIGDDAILIVTAGDAKIDNKKYKAEFNCKAKMLTPEEVLEFTGHAIGGVCPFG
                     LKNSIKVYLDDSMKRFDTVFPACGSSNSAIELTCEEMEKFSKSEKWVDVCKNW"
     gene            complement(49423..49965)
                     /locus_tag="PC466_001131"
     CDS             complement(49423..49965)
                     /locus_tag="PC466_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768525.1"
                     /translation="MKKFIKVSFFILGIFTLFIAINKLVYRDMVSVKDYEINHLEEIV
                     FDFDSRRSRDIGTIVRFKISNNSKYSYKLNSAKMKFENCVENKKGMNKCSAYVNVDLF
                     NEKNSITESTLKYGIKPNNQGYVDFVIPKGLNFDYRYFNESGMSVEYKGEYIVNIPMA
                     KGLYLVVGKNNDTWNANIME"
     gene            complement(50017..50703)
                     /locus_tag="PC466_001132"
     CDS             complement(50017..50703)
                     /locus_tag="PC466_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 transporter permease"
                     /protein_id="HDF2768526.1"
                     /translation="MFNLIRKDLIIGISSDGIRNLKYILLFFVFYFFLNSISYYTVSI
                     VVSYLIFINTFECDYENDSRIFIRSMPVSIEDIVYSKYLLGVGLIISVTIIVSLLSKL
                     TSLVFFRNMVLNDVFFSVNIFLAILTILLPLIFKFGYGKMKVCGFIVSILIYFVYGSL
                     LKMISMIVYQVKHFNYSKVGGVYLSNYVTDIANTKYINLYSMTFLTIIIFIISMYFSI
                     KISKKNKFNY"
     gene            complement(50691..51563)
                     /locus_tag="PC466_001133"
     CDS             complement(50691..51563)
                     /locus_tag="PC466_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2768527.1"
                     /translation="MFSIRNITKKLGKFKLNNINLELKEGDIVGIIGPNGSGKTTLIK
                     IIMGIIDADEGEIELCNETIENSPISFKNNIGFVYDSLQFYPHLKVKEFRKIVSLFYK
                     NFDREKFDEYLNKFDIEENMHIENLSKGQSEKLMLSSALSHNAKLLILDEPTAGIDPI
                     VRTEIMQYLQDFVKNGSSSVIISTHNTDNLIKIADYLVFINRGNQIFTVKKELIEQEY
                     KIIRANKAELEAIKESIVGVKEYKYYNEALVKVGDSLKVKSLLIEIDKHKVKNPTIEE
                     LMYYYVNEVRGCSI"
     gene            51698..52498
                     /locus_tag="PC466_001134"
     CDS             51698..52498
                     /locus_tag="PC466_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+)/NADH kinase"
                     /protein_id="HDF2768528.1"
                     /translation="MKRIITINTNQLNKSLETKELLTRKLINAGFEVYSDIYPDTELI
                     ISIGGDGSFLRTVRDFDFPEIPIMGINTGHLGFFPDILPDKIDSFIEAYTKKDYIIQE
                     MSLLNAEVYTTTSGSNMLAVNEVVIRGDKSRTIHLNLSLDNKHIQNFSGDGMIISTST
                     GSTAYNYSAGGSIVDINLELMQITPLHPINTNAYRCFTSSIICSNESVIKIAPEYRFE
                     DSVLIVVDGVEHRFRQIENIKVSISDAKIKLLRMSNYEFWHRVSEKFL"
     gene            52523..53092
                     /gene="yfcE"
                     /locus_tag="PC466_001135"
     CDS             52523..53092
                     /gene="yfcE"
                     /locus_tag="PC466_001135"
                     /EC_number="3.1.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphodiesterase"
                     /protein_id="HDF2768529.1"
                     /translation="MKIGIMSDTHGSLLYFEKALNVLSDCDVLLHGGDVLYHGPRNDI
                     PEGYNPKKFIETLNKLENIVIVKGNCDADVDQMVIEHPIQSPYVMSQFGEIRIILNHG
                     YIESEEEIIDKAKKMGGDILVLGHTHVKKLYMDDNLIVINPGSTSIPKDGSHSVAIID
                     IIKTDDEDELELDINLIDINTGNIININD"
BASE COUNT        17309 a         9419 c         5580 g        20988 t
ORIGIN      
        1 gtatctagct atcttaaagg ctaagatgat agaaggatta tacctaccat tttctaatga
       61 acctatagtt tgtcttgata cttgcaaaat agaagcaagt tcttcttgtt ttatgcctct
      121 ttcttttctt atttcttcta atctattttt cacatctatc cccctttaat atctcaacta
      181 cggaaagtct actttccata attatacaac tatatttcat ttatgtaaag cttgctttcc
      241 atatttacaa aaaaataaca gactattttc agcctgtaat tttaaaattt catgttgttt
      301 attaaattta atgttattca ttaactttaa cttggtttct gaattggaat ccaaacttct
      361 gtagtataat caggagcatt gatatcgcca ttgggataaa gttcaatatc tggtaagtta
      421 gcatacacat acccagaact tggtaaccac tcagtaataa ttcttttttg caattcctgt
      481 attgccagag catttggcat tggagaaaca cattcaaata ctgcccatgt acctgatggt
      541 attaagtatt cacgagtatc ttctaataca ggcttatctg ttggtgcagc aatataataa
      601 tctaaaccct tactatttgt acacacacta actccaagca atccacaagg ttcgttattt
      661 attaactctg aaagtttatc aattgttcca ttttttatgc atttagccca taacttagga
      721 actttctcaa agcactcttc tacaatcatg ttcatacttt cttttatacc aacaatacga
      781 aaccctttct tttctacaat acgatattgc atttctacat ttccttttac ataaatgctt
      841 aatgtcatct taggatatgc ttttaaaaca acaccctttg ctctagctgc agatggagaa
      901 atgttatgta tattttgaaa agctctatta aaagatgttg gtgaatcgta accatacttc
      961 tcagatagtt ctaaaatttt gatgttactg ttctgaagtt caaatgcagc cttagtcata
     1021 cgtcttcgtc taatatattc agataatggt acttctgcaa tatatgaaaa cattctttga
     1081 aaatgaaagg ttgaacaaca tgcaattttt gctgcttctg cataatccac tccactttcg
     1141 agattttctt caatataagt aatagcttga tttaatttat ttatccattc catttgatat
     1201 tacctccaag caaattatac agtttaataa aataatatac ctctctattc atgcacaaaa
     1261 ttgtaagcat ttaaattcat aagtattttt caatcaatac aataaatata aaaattgtat
     1321 tatacaataa aaaagttcaa taacatttta ttataaaata ttattgaact ttttataaaa
     1381 attaatttaa gtgtagttaa attaagtatt aaactatctt atatattaca atatcctact
     1441 atcttatagt cttctggcac tttataatct ttgtctggag tacctaaatt ccattttaaa
     1501 tcaaacatag ttgcacttat tattgttgca aaataaagca taactatacc aatgtctatt
     1561 ttttcttcat ataaattagt atgaccatct tttctaacag ctaaaactac agtgcctcca
     1621 tcaactataa atctccatgg ttgtctattt aatgtagatg gagctaatct tgcatagtga
     1681 aatgcatcaa gaagtgctct ttcttctaag atttctatac ttgcaacatt tccccattcg
     1741 ttcatataaa caacatcttc tacacctagt ctagtagacc ccttatctgt tacaacttgc
     1801 atatcagatt ttgaataatt ttgcccagtt tttgtagcat ttaatacttt agcattactt
     1861 acattttctc catatccaat agctataatt cctgttacct ctttatctga attaattcca
     1921 agtttttctt ttaccttttt tccatcttca aaagtaaccc aacaagaacc aattccaagt
     1981 tctgttactt taaagattat actttctcct atgtaccctg aattttcaat gtaattatct
     2041 tttatgtcag ataatattat aatataactt ggagaatcta tcatatttcc tttgtaccct
     2101 gctactttat ctaaattatt aaaaacttca cttttattca taattcttac atcaacatct
     2161 atttctggaa ctagtttctt acaagattct gagtatttct taatttcact aagatattct
     2221 tctttaatat ctatgttctt atattctcta acagactttc tatttaatat gattgtttta
     2281 taatccataa ttttatcctc cccaaactag tattgtctta attatatacc cattaatata
     2341 ttattttact catttattta ataaataaag attacaattt tgtaattatt atttattaat
     2401 aatattccac ttttacatta ataatgacca gttgtgcaaa atccattgcc aaccaccaaa
     2461 taaaaacata ttataaaagt aatataaaat aacaaacaaa tcttaacaaa aaattaaact
     2521 ttttttacac gaaagaaggc ttcccgttgc cttctttatt tttataaaaa aataagctgt
     2581 ttctaaaatg atttcacatt tttgaaacag ccaagttatt ctataatgac aactataatt
     2641 tgaggatgtg agggagagtt gtcattataa atttagggta attatattat gttttaagct
     2701 agttcttcct atatttatat aatacatttt atatatgaat tttatatgag attggtataa
     2761 atgatatatg aaattacata tgtttatatt atattaaatt ttattattac attttccaca
     2821 acaatactca tatgtctcca cattatttgg aatatttaca aatacaaatt ctttacagtt
     2881 ctcacaatac tttaatatag atatagttcc acaagtgtaa cattcaaata ttacacaatc
     2941 ctcattttcc tctactattt caaacttttt actatgttca ccacactctg ggcacttgtg
     3001 attatttaca ttcataaata ctcctcctta ttagtatagt tacatttcaa aaacttaatt
     3061 aatgtattct atattactta ttatatattc tataataaat catattctaa tataataaaa
     3121 caaattaaat aaaaaaaaac cataaatttt aaatttatgg attaattctt gtaatgataa
     3181 ctctatttga ggatgtgagg gagggttatc attacaatag ggtattatat tatggttttt
     3241 aagctagtct ttctacacct catatgatac atatgctata tgaattttat atgattttta
     3301 cataaatatt ttatgaaatt taaatttttt agtcattttg aaatttgtaa aaagttctct
     3361 aaaaatccac agcatcataa acagccaaaa tttaagtaaa acatcataaa aaaatttgtc
     3421 caataatttt aacaagtcat ttcacctcat tataattatt gacacaaact taaataaaca
     3481 atctataaat cttatataaa tcttaaactt tacccttatt gatacacaat ttctagtttg
     3541 tcaattttat tttgcatctc taagaaaatt tcttcaacag aattgttaaa tatattgcct
     3601 aaatagactc ttttatcttt ttgaaatgaa taagatttta cactaccatc agaagaaata
     3661 tataaatgac tccactctgc tccatatttt gaaaacctct cctttgtatc tttaaacctc
     3721 atatcttcta tttttattgc tttttctctg tctcctctta ctacagtgtg accccttttt
     3781 attaaactgg ttatttttat atcttctttt aatttaatac gtgtatcatc attttttgaa
     3841 tatactttcc atatcacttt atgacgataa ttatctaatt cttttattaa gcttctatca
     3901 atagtaaagc tatctttagt taccacaatt aaatcaaaat ggtctaacat atattgaaat
     3961 atttctctca tacttttatt ttttaaaata tcctcaccaa taacctctat aaatctacag
     4021 cctttctcat acatgcagtt caataaactt gtgatttcag aaaaataatc atttgtatta
     4081 ttatctccat ctatttctat agtaaagtac aaaggagtaa tgtatgattt atttcctgtt
     4141 atctcaaata cacttgatag tgtctgtata tcatcttcaa acgttaagta tacattctca
     4201 taaaacataa aaaattccat aactttttct ttcatattat ggatatttct atatctattg
     4261 gataatatat ttattatatc gtcagtagta tttttcccat cacattcagc cagtataaca
     4321 atttgcttcc aacttaagct atccacattt ccgatacttt ttttatatcc atcttcttca
     4381 tcataaatag gaccaattat aatgttttct tttggccaca gatgaaccct agttccatct
     4441 tttaatttcg gatatttatt ttttacagac tcataaaatc tacttgtatc acccatgatt
     4501 ctttactccc ccccatagtt taaatattct atgctaaaaa tagcacttta tttttattaa
     4561 ttcaacaatt attcaaaatt ggtcattata tatgtttaaa tggatttaac atcaacctta
     4621 tttatatgtt attgatgttt atatatgtta tataaaatct tatttctcat acttcaatgt
     4681 aatcttaact atctctggtt tacaattaag cctaattaaa acttttgagc ctcctaagcc
     4741 tttatttaaa atcatagtgc tattatcttt ttcatatttt ccccagtcat acttaggaaa
     4801 gaactctcta tttggagata atacacctcc aacaaaaggt attcttatta tacctccatg
     4861 aacatgtcct gctaaaacca aatctgctcc ccattttgca tatttttcaa agaaaaatgg
     4921 tgtatgtgct aaaagaatgt tatattcatt ttcattaact ttacctagat tgtcttctac
     4981 aaaattgtca cttagttcta attttttgtt attagcaaat aaatatggat agcattccaa
     5041 tggtataatt aaaccatata aattaagatg gctattacct ctatatattc ttacagattc
     5101 attttccata tttattattt tctttgaata tagttcctta aaataatcct tatatagatg
     5161 tttatacttt tttattaaag atttttgttc atgatttcca attatatgat atacttcata
     5221 tttttcaacc aaattatcta ttaaatctaa tgcaacttga aaatttttat tttctccatc
     5281 tactaaatct cctgttataa atataacatc tgggtttaat gattcaattt tatctatcaa
     5341 taccttatta tttttatcaa acaccttatt atgtaaatca ctcacttgaa ctattttaaa
     5401 gttatcaaat tcctttggaa tttttttgtt gaaaatagta tattctgtcg tttctatatg
     5461 ctgagtttca tacttataca gaatatacaa taatattaat actaatactg tcattgaaac
     5521 ctttataatc atattctctt cctctttatt ctattttgtt aatattatta taatgctttt
     5581 atgttttttt taaaacaata acatcatcac atacatataa atcttttcga cattataaaa
     5641 ataagttatc cttttctaaa attttcattt attttagaaa aggataacta taaaattatc
     5701 tataaacctc tatattgtga aatatagttt ttcctttatt taaattttta tatatatgct
     5761 ctaaagttcc atcaaaccta atagaatgtc cagactctaa aatataagtt ttcccatcca
     5821 cattaaggtc aagtttacct tctattacga gtacatactc ttctaaaaca taactatgtg
     5881 tagatgaaac atgagtacag ttttcctcaa gctcaattat aaaaagttca aaccttcttt
     5941 gagggctaaa agggtatatt ggatataact tcatgttccc tttttgctca acaataggct
     6001 ctacttcttc tttctttata acctcatagg tatttgtatt ttcatttaat agtgtagtaa
     6061 aatttatttt aaatccagat gaaattttcc ataaagtaga tactgtcgga cttgattcac
     6121 ctctctcaat ctgtccaagc attgctttac tgacacctgt catctttgaa gctttgtcta
     6181 aacttatgcc catttcttgt ctcaataacc ttaaattttc tcccacatta ggaaatttat
     6241 tatccatgtt aaaatcctcc tgatagctat ttgtattcta tgatttttac tcctgtaagt
     6301 tctactatct cttttaattt taacatatga ttgttacaaa tttcatcaaa ttcatatata
     6361 taatcttcaa gccctaatgc cttatattta tcgattccaa atttatgata tggaagtaac
     6421 tccatcttgc ctcctggaac attttgtttg acaaataatg cagtatttct tatattttct
     6481 tcactatcat ttactccata aataattggc actcttataa ccatagattt attcaacttt
     6541 gaaagcctac atatattatc taatataatt ttattactta ctcctgtata ttctttatga
     6601 atattatcat ccatagattt tatatctaca aatatgtggt ctattttctc aaatacatca
     6661 tttaccttat tccaatcaaa atatccacaa gtttcaattg caatatttat gcctttatca
     6721 taaaaaatat caactaattc tcttaaaaaa tcaatctgaa gtgtaggttc acctccagaa
     6781 aaagttatcc ctccattaga ttcaaagaaa aatataaaat ccttttcaac ttcctctact
     6841 atttcttcaa cactcatttt ttcggtcatt atacaaatgg catctttaag acataccttg
     6901 atacactctc cacataaatc acatttatta tttatttgcg ttctatcaaa tagtgaactt
     6961 atattttgag gacaaacatc tatacatcta ttacaggata cacatttatc tttcataaca
     7021 cctaatttta ctatgttact ccaggaatct ggattagaac accacttaca ttttaattta
     7081 catccttcta aaaatatagt agtccttatt ccatctccat catttactga aaaatgttgt
     7141 acttttacaa ctctaccttt tttactcata atctacctca taattaaaaa ttgctatgtg
     7201 aatttctagc tattatagca tcttgcattt ctcttgataa attaacaaat tgagtactat
     7261 atccagcaac tctcactaat aaatctttat attcttctgg attttcttga gcttttaata
     7321 gagtatcatt tgatatcgta ttaaattgta catggaatcc tcctaaagca aaatatgatt
     7381 taatcataga tgttagattt ctaagtcctc tttcagtttc caccaaatct tgattcagtc
     7441 ttaaatttag aagtgttcca ccagtatgaa catcatgatt tatttttgat gcagatttca
     7501 tggctgctag tggacttgtt gtatcagtac caacaaacgg agaaactccc tctgtcaaag
     7561 gttttgtcgc ttttcttcca caaggagttg cacctacgat ttttccagtt ggtacatagt
     7621 ttgatatacc cataaatgca ctattaaatt tagagccaaa aatatccttg tattttctag
     7681 tttcagtata ataaaaatca gaaacttcaa ttgctaatga atctacataa tcattatcat
     7741 ttccatactt aggaacatcc aacgcaagtt ttcttaattc ttcataacct tcccaatcat
     7801 tatttagtgc ttttgttaat tcttctagcg tagtcacctt atcctcaaat actaattttt
     7861 ttatagctgc caatgaattt gaaactacac ctaaccctat accagttaat acaggaccta
     7921 tattatattt tgctcctcct ttacttaaat caactccctt atccaaacat ccatctacac
     7981 aagtagataa aaatggtctt ggtaccattt ctttatgaat ttgttgagca acagtagttc
     8041 ctataacaga actttttaca agatatgcta attgctttaa aaactcatcc ttaagttctt
     8101 caaaagaagt aaattctgtg atattttttg tatctaaccc cattttttct ccagttaatc
     8161 tactcttacc ttcattcata gcatattcta aagctgctgc aaaattgata tttacggctg
     8221 aagtccactg tcctgttttt ctaaaatgag gaactacaca accacagtta ctccaatctc
     8281 tagcatcttc tgcatcatat ccatcttgta ataacatttg tgcccctgca ctatcgctgt
     8341 gtatagcagg gaaaccagtt ccttgtttta ccaatttagc aactgccatt acgaaattat
     8401 ctggtgctcc ttgactcact ctaacactta atcctggctg gtgagttttt acactttctg
     8461 tagcctttaa acacatatat gagatatcat tcgttccatc agtaccattt ctctttttac
     8521 caccaacagt aagattttgg aattgattat atcctgcaaa gtaatttgct gtatttgctg
     8581 atatagtcca tacccattct gataacttaa tccaaagtgc ttctatcaat tcttgagctt
     8641 ctgattcagt tattttacct tctctagcat cattttcata atatggatac atatattggt
     8701 caaatctacc taaatttaat gccaatggat tttctgatag aataccacct aattgaacaa
     8761 accatacaaa ttgtattgct tcataaaaat tagttggagg gtttgctggt acattcatac
     8821 atatctctga aatttttata agttctaact ttctcttttc atctgtttct tgcttactca
     8881 tctcttttgc aagatttgaa tatctttgtg ccaatgtcat aataccctct gcaactatag
     8941 aaacagattt gtaaaaatct atcttttcaa tattttctga aactgatata tctaattctt
     9001 taattttttt atctgcatct tccttaatcc ctttatatcc ttttacaaac aatatatctt
     9061 gataatctgg tgttacttca ccaactgcct gtctccactt agaatcatta tctattattc
     9121 ctgtatctac taatatctta gctgtatctt ctgggattct tgctaagaaa acttcttcca
     9181 aagattttcc cttccaatat ggaaatattt cttttcttat aaattctatt tgttcttttg
     9241 atattacata tgggtcttga gttcttttat caaaagtatc catttctttg tctacccatt
     9301 gccaagaaaa ctctggtgtc aatatccctg ttcttctaaa ttttcctgct gtacctacta
     9361 ttaattcatt ttcaaagatt tttataggaa gttctttaca tgtctccaaa aaagctttag
     9421 ctcttcttat acagatagct tctccctcag tttttttatg tgattctgta aaaattctag
     9481 ccctttcaca acatatcata ggtttagaat taatatattc ttgtctaaat gcttctattc
     9541 tattagtttg actcatttaa aatccccctt tggataatat atactacatt tttgtatgtt
     9601 ataacatact ttaattatat tatactgtcc tttagcataa aatggaagca aaataacttt
     9661 ttttttcatc taccttgaac acctatatat taatactttt tttgttaaat ttataaaatc
     9721 taaaaaaatt ttctatgata tattttctat attgttatag ttatttctaa tatactaatg
     9781 atttgaaata tcaaatttgt atactagact tagttttaaa accttagttg attgtttaac
     9841 tttgttaact tcaacatgta tatccttcat ataaggaagc tccacaacac ctactccctt
     9901 attaaattct tcttcaacca tagaaaaaat ttctttctca gttaagttcg tattagtcaa
     9961 tgatttaaat aaattgtata taaatttaat atatttatca ctctcagata acttatcatc
    10021 ttctggatac tctttagcac agagaatatc tattgttact tttccttctt tatcgtcttc
    10081 agacatagaa tagaataaac ttcgaatatt tttttcaggt ggtttttcag caccatttat
    10141 agatactaca aagctaccat ctgattttga gtcagtaata ctataaccac tgtctattat
    10201 agctttcgaa aatctttgag ataaatcttt ttttacttct tctctacctt tcgcatcatt
    10261 aatcttttgt gagtaattat taaatagctc gatagattca tcttttttat cttcaacttg
    10321 ttctttcaat gaatctttac taatttgttc tgagctactt aagttcttat cagatacagg
    10381 agacatacat cctgccatca atgctaagct aagatttaaa gccacaatta ttgccactct
    10441 atttatattc ctttttactt tcatacacaa tcctcccatc acactaaccg ctctaaagta
    10501 ttattcattg cattagaata tatttatatt ttctttatat taaagattta ttattcaata
    10561 catatcacct tcctatccaa ttcttataac ttactattag taaaattata agctccttaa
    10621 tacagaaata aggatgttat cttttgttat taaaagataa catccttatt tttttgtatc
    10681 aatacatatg tcccaactgg taacttaatc gccccaactg tcagtatctt gctccaatgg
    10741 tatatatata tttagtataa atttatcgat actattttca aataataatt ctccattata
    10801 tttttgtaaa gaagatttaa tactctgaat acctattcca tgtacgaact tatccatttt
    10861 gtttgttaac aatatatttt tattaaaagt aagctgattt agtttactat tttcacattt
    10921 aagtacaaaa aatgactttg ttatagttcc tttaattcta atatatttat taatattttc
    10981 atccactatt ttatcacatg cttctattgc attatccaaa atattagaaa atatgcttga
    11041 cacatctata ggttttacaa aatttacttt tgaaaaattt atagagcaag taaatttaat
    11101 tccttttttt aaacatattt cactcttttc gttgattata atgtctaata tcatatttcc
    11161 tgtattatag atatatttaa atgtttttat ttcatctttt aaattgttaa catattcatt
    11221 aatttctttg ctattgtttc taaggttgtc tatacaataa atgtggttat ttatatcgtg
    11281 atatagtttc ttaactcgca tatgagattc ttgaatactt aaataatgcg catattgcat
    11341 atctaactta ttttttatta attcagcttg agattttaat ctattctctt ttattatttc
    11401 tttaaacaat aatataagaa atatactact agctcctacc aactttggat taacaaaatt
    11461 atcaaaatag tatccttctg aatgtaatga cccaaaccgt tctaattttt ttaatacata
    11521 atttacaagc atattcattg tattagctaa taaggcaaat aataaatata cataatttct
    11581 cttatcttgg ctaattaatt ttatagactt cctaaaaaag ctaaatacaa gatatataag
    11641 aataattatt aaattactat atatctgaat ttttatagat tctaagtgag gtactaataa
    11701 ggattcttta gatgaaataa cattacctgt aattgcaaaa aatagtattc tatatataac
    11761 agcatccaaa catttataat atacactaaa tagataaaag aaaatggaat acttaatata
    11821 atccatctta taaaaataat tatagtatcc tccccaagca ataaatgcta atatataaaa
    11881 taaatagttt atattactaa agtaacttcc tccattaaat aatctactta tctgaattat
    11941 aatataaata agaaacaaga caatatagaa tactattttt tcattttttt tactatcctt
    12001 tttataaatt aaaattccgt tcattataga aaactgtata aatatagata aaactactaa
    12061 tagctcattc ataaaattta gcatattgta tcaccaagaa attttaaaaa tttctcctta
    12121 acttctttat atctatatct actaataggt acctcttctc cactttccag tattgcagca
    12181 ttaggcttta tattttcaac atatcttaaa tttactataa aacttttatg gcatcttata
    12241 aatttatatg gatttaattc tttttctatt ttacctaaac tatattttat atcaaaattc
    12301 ttgtttattg tgtgtattag catatctttt ttttgaactt ctatatattt tatttcattt
    12361 aaataaatct tatatgtatt agacttattt tttattgtaa tatgactttc cttatttatt
    12421 tcaatatctt tgatacaagt tagcacatgt ttttttagtt cttccaactc tattggcttt
    12481 agtaaatacc tataagctct tacctcataa ccttcttgca cataatctat taatgaagtt
    12541 acaaatatta tttccatttc atcgtctact tctctaatct ttcttgcagt atccattcca
    12601 tttaattttt ccatttttat atcaagaagt aatatatcta tatcttttaa attactttcc
    12661 agtaactctt ctccagatat atacttttgt atctcatatt ctatacttat atcttttaat
    12721 atattctcaa ggtaatcttc tattaaaagt tgtgtttctt tttcatcttc acaaactgct
    12781 atcttaatca taaaatgcct ccttacataa tttctagtta atacaattaa aatatttata
    12841 atatatttaa agataatttt gtatatctga tactttagga taacattttt aaattatttt
    12901 tatcaatact caatccaata caactattat ttgatatttc aatttaaaga cagaaattac
    12961 tataattaaa aacagtactt tactaacaaa agaagatgtc ttaaaatatt aaaaaaataa
    13021 ttttaggaca ccttctttta tttatttaaa ctttttaagc cttaaataat acattaatct
    13081 cctatataat tgtactgcat ataaaatcaa caatataatc tgtagtacaa tagcagttac
    13141 agatgctcca taaccactat ataaatttct tatttcaata ttcaataaat atataaatat
    13201 tactactaac ataaagaata taaacatatt cataaataaa attgacttta ctttgttttt
    13261 tttatcagaa tcactatata atttaggagg tatgtctttg tattctttcg accatatata
    13321 ccatgcagat gtacccataa aactaccaat actcctaaat acaagattcc agccatttga
    13381 tttatgttca tcaaaataat tattctctac atcatagtag taatcaacag tgtattttat
    13441 ttttcttgga cttcccttat gaaaataaaa tattcctcca aatttattta tcttatataa
    13501 attatatcct ttagcttcaa tatcttctaa ccatttctct atcttatcag gtgaactata
    13561 ccagtcaaat ttgaatttta ttttcttttc catagcactc attctccaaa atgatatttt
    13621 taaatagctt aaaaatctat ttaaataatt atatcatttt gatactaatt ttaggttaca
    13681 atcatatatt taaaaagcta tttaaatagt aataaactaa tagccataac acccattcct
    13741 gcaatcaatc cataaataga taaatgatgt tccccgtact ctctagctga tggcaataat
    13801 tcatctagtg atatgaatac cataattcct cctacaattg caaatacaat tccaagagtt
    13861 atatcattta aaaaatttct aagaagtaca tatccaataa tcgctcctaa aggctcagac
    13921 ataccagata aaaaggaata ataaaaagct ttctttttat ctcctgtggc ataataaact
    13981 ggtacagata cagatatacc ttctggtata ttgtgtattg caattgcaat tgctatcggg
    14041 atagctattg taacatcatc aagagctgat ataaatgtag ctaatccttc aggaaaattg
    14101 tgaattgcta tagccattgc tgtaaatata cctgttctca aaagagactt attttttttg
    14161 atattctttt cttctatatt ctccattttc tttatttcat gtggattttc ttcttgtgga
    14221 attaacttat caataacagc aatgatagcc atacctataa aaaaagctat tacagttgac
    14281 caacttccta atttctctcc catagatttt gtcaaagcat cttgtgcttt aggaaaaatt
    14341 tctatcatag aaacataaat cataacacca gcagaaaatc ctaagcttat agaaagaaac
    14401 ttagtatttg tttttttagc aaaaaatgct atacaacttc ctataccagt agataaacca
    14461 gccaataatg ttatcaaaaa tgcaaatatt acattattca aataaatcac cttcttttta
    14521 attgatattg attatcattt tctttatgct atcatatata ttttatatag tcaatattta
    14581 taaaaaatat acacaataaa aaagcagaga tataaactta gtctctgctt tttctttata
    14641 gtatattaaa attatttatt taagaaatcc actgcatatt gcacatataa agcagttcca
    14701 atttctagag catcttcgtc tatattaaag catccatgat gatgaggata gcaagcacct
    14761 tttgactcat ttctagctcc tacaaatgct agtgcaccag gtgctatatt cataaactca
    14821 gctaaatctt ctgctcctgt tactttttca aatagtgtta tacagtcttc tccaaatagc
    14881 ttaattgctg catctgtagc tatctttgaa cattctttgt catttataac tgctggtgtt
    14941 aagtacccat actctaattc agcatctgct ctatatgctt ctgctgtaga ttttgctata
    15001 cgttctaaaa ttccaggaat ttgctttcta agctctggat taaatagcct tattgtacct
    15061 tctaagacag cttcactcgc aattacgtta aatctagttc cagaatttaa aactccaaca
    15121 ctcacaacta atggttccag aggacttact tctctactaa ccatagattg tagattcata
    15181 actattgctg aacttgcaag cactgcatca acaccttgat gaggaagtga accatgacca
    15241 cctctacctt ttacagtaat tttaaagaaa tcggcagaag ccattcttgg tccttcttct
    15301 accgatatag tcccagattc tacatcagtc caaagatgta ttccaaacac actatctaca
    15361 ccttccatag caccatcttg aatcatagct cttgcacctt taccaacttc ttctcctggc
    15421 tgaaaaaata attttacagt tccattgata ctatccttaa tatcatttaa cacttttgct
    15481 gcccctagaa gcattgatgt gtgaccatca tgaccacaag catgcataag tccttcattt
    15541 ttagatttgt attctacatc agtgcattca acaacttgta gagcatccat atcaccccta
    15601 agtgctacag tctttcctgg attagctcct tttatagttg caattacacc tgtacctcca
    15661 gctgatacat atggtatctc tattttatca agttcttctt taactctctt tgatgttcta
    15721 acttcttcca tacttttctc aggattttca tgaaattccc ttctaagctt aattacatag
    15781 tctttataac tctttgttat ttctttaata tccattccat acctccaagt agtacacatt
    15841 cttcttattt aaaatacttt ttatcactta aatactatat tagatttaca aagatacctg
    15901 ctattactac agaagctatt gtaactgtag taaatcctcc aacaagcatc tttggaagca
    15961 tcttatccat taaaaattct ttttcttctg gtgtttcagc caaagccttt actgcctctt
    16021 cagttaatat atagtttggt ggaaaaccat aaagtgatgt aagcgaaact gaaaaagcca
    16081 tttctttact ttcacctaaa agcttaccta ctataataga gaatattccc atacctatta
    16141 caccaaatat tatgattcct acaagaggaa ctgccatttc aacaagcatt gctggtgtag
    16201 cttttgctaa tcctgcaaat ataaaagcca tcaatgatgt cattaaccat ccaaatgaac
    16261 cagatttatt aagtggtttt ctatcaacta ttccaagttc tgatgctatt acaccaaata
    16321 ttaaacatat aacatatctt gatacaactt catttgtaag atttgtaaat tgtactgcta
    16381 accatgctac aaatcctaat ctaagtatta tcatatatgt cgtatcatat ttttctggta
    16441 agtctggaat tatcttaaat ctgctttttt gttcaggtaa atccttaact ttttcttcat
    16501 ctgtatttac agttactttt ccacttctaa agtctgataa aagtcttttt ccttcttttt
    16561 taagcattaa tgctgtaata ggataacccg caaatccttg tgcaacatac atcaaaattg
    16621 caagtactga taaacttgca agaccttttg ctgtagcagc atctgccatc attatagatg
    16681 caactagccc tccagtaaga ggaggtgtag ctattactgc tgtatcccat ccaaatacta
    16741 ttgtccctaa tgccaaagca cctacacata ttcctactat tcctgccaag gctattacta
    16801 ttgttttcca ttgacctgct aattccttaa tactcatcat agttcccata tgagttatta
    16861 acaaaagcat acctaattga gctaatggtg ttcctaaagc ggctaagtcc acaatatttt
    16921 ctgggaaaaa agtccagaat cctactataa atataattgc tgatacaaaa accgacggaa
    16981 caaaagcttt agtttttgct gaaactatat ctcctatcgt cagtgatatt aaaactagac
    17041 aaaaagctgt tattgcctcc atacaaaatc ccccctcata ataaatgtat ttttataaaa
    17101 tgtatgtata gttatccatt attttactac ttttgaaaaa catttcaagt caaaattcga
    17161 cttttttcat aaaattcgat aaattccata aattaaagtt agttttctaa attattcttt
    17221 ttgtaaaaac gttatcctga ccattggcta tttaactcta ttcttacaaa gagaattaaa
    17281 tgtaatttgc aaaaaataaa acataggata cattttattc ataaaacatc tcataaatat
    17341 aaaatgaatt gtctttatga atcttaatat atcctatgtt tgtaagttta atgcgtatgt
    17401 tagctatggt gtaaaatttg tatactagtt attgtgtaac ctactatata ctccattttt
    17461 gtttactaac tcttcatgag tacctctttc ttcaattcct ttatccgtca atactatgat
    17521 ttcatcagca ttttttatag tagtcaatct atgtgcaaca actaaatttg ttctatcttt
    17581 acttaattcc tctaaagact cttgaatttc tctttctgtt acattgtcta aagcagatgt
    17641 agcctcatcc aatattatta ttggaggatt ctttaaaaag attcttgaaa ttgaaattct
    17701 ttgtttttgc ccacctgata attttacgcc tctttctcct atataagtat catatccatc
    17761 tggcaaagtc tctacaaagt catgtattct agctttttta gcagcagcta tcatttcttc
    17821 atctgtagca ttagggttcc cacaaagaat attatctctt atagttcctg taaataaaaa
    17881 tacatcttgt tgaactatac ctatattttt tctcaatgat tttaaactaa catcttttat
    17941 actctttcca tcaattttta tatcaccctt atcaaattca taaaatcttg gcaatagatt
    18001 acataatgta gtctttcctc ctccagaagg tccaactaat gctatagtct taccagcttt
    18061 tatagataaa cttaaattat ccaaaacttg agtcttatct tcatatgtga aagatatatt
    18121 ttctatctca atgtcacctt ttacattttc aagttcaata ggatttttag cttctttttg
    18181 atggtcttgt tccattatct ctatgaatct tttaaaacct gtcataccat tttgatattg
    18241 ctctgtaaaa tttattaatt ttttcatagg ttgtataaac atttttacat atagtatata
    18301 agcagcaaaa tcacccaaag taatttttcc tatataagta aaataaccac cagctattac
    18361 aactacccac tctaagatat ccatgtataa attcatacca gagtaatatt ctgccattac
    18421 cttataagaa tcttgtcttg ctcttctaaa taatttattg cttcttacaa acttatttaa
    18481 ctcttctttc tcagtacaaa aagacttagt tactttcata cctgctatac tattttctaa
    18541 agtagcattt acatcaccta tagtaactct actcttcata aaagcaatat tcatcttatc
    18601 ttttttagct attgcaaacc aaattataaa cggtaatata gcaaatatta taagcgtaag
    18661 aggaatattt atatctataa gtataaagaa tgaaccaacc aacattacta tagaaatgaa
    18721 taaatcttca ggaccatgat gtgcaagttc tgttatatcc attaaatcat ttactattct
    18781 agacatagtt actccagatt tgttattatc aaaatacgta tttggaagtc tttgtaagtg
    18841 tgtaaatacc tcatttctca tatcagcttg catatctaca ccaataacat gtccccaata
    18901 ctgcataaaa tagttaagcc ctgcttttgc tataaatata agtataagtg ctactgcaaa
    18961 aactactaac attcttaagt ttttatttgg aacaacgtca tccattatat ttctagttat
    19021 cataggataa actaaatcac ataaggaaaa tagaaaagct gctataaggt ctagtgtaaa
    19081 aattttctta tatggcttat aatatttgac aaattgtttt atcataagta ttaaatccct
    19141 cctttattag tacttctata tagtacttct aaaaaatacc cataaattag tataacataa
    19201 caataacttt aaatctttta taaacttaca aagtaataac aatctttttc ataaaattga
    19261 agatttatat catatagttg tatacttgaa acagcataaa aagagctata tctctatatt
    19321 taaaatttta taaagataca actctatatt taatactaaa ttttttttat aaacacaaaa
    19381 ctacttcaat gcatttaata tctttttatc taatgctgtt gtatttatac ctgttatata
    19441 tcctgttgcc tttattgtag gtatatcata agttgttggt agtatagtag tagatacgat
    19501 taaatcagca ccttcttgtt ttgttgaaca ttcagcaatt ttacattgct caacttctgc
    19561 gtgtatatta ttttctttaa ccaatctttc tactctgtca caaactattg ttgatgttgc
    19621 gattcctgct ccacatgcta ctaatatttt tttcatatat tgtcctccta caatttcttt
    19681 aatattttat aactcaaaat aaaattgata aatttcttat atctttattt atataaataa
    19741 ttatatcatt ttatataaga agaacatctt aaaattattc ttttaatatg ttttttattt
    19801 caacattgct tatacttaaa atttcatttt ttatacaaga ctctatgtac tttgatatat
    19861 ttttataatc atttaaatta aactgttcaa tattcaattt atattctata tcactgacaa
    19921 tacctatcaa atcagactta ttagataaaa tatcctcata cttacctttt ctagttactt
    19981 ccaatctttt aaatctataa tttttatatc cttctatgat aatcaagtcc atatcttcat
    20041 ataattgaat cattttatat aatggattct tctcttttag ttcttcaata tatgctactc
    20101 gtttatctga tattatacag acttttctcg ccccagattt tctatgttta taagtatctt
    20161 ttccttcctc atccatatca aaatcatggc aggtatgttt aataactcca acacgatacc
    20221 cttttttatt taattctttt attatgcctt caatcaacgt agttttacct actcctgaat
    20281 atgagacaac tgacaatata ttatacataa aattgtgtcc tttcataaaa ctatctaata
    20341 acaatctcca ctaattgatt ttcttttatt gtctcattct ttttaatctt aatcatacaa
    20401 ttacttctta gagttgcaga taatctagct tttgcatctt tcttatcatt tagctctaca
    20461 tacaatttac cttcacttgt atatagtttt ccacttacaa atctatcttt atttgaaagt
    20521 ttattaaatt ctcctttaaa tatagctttt atatgatgta ttcccttctt atatgttaaa
    20581 tactcaataa caggaactat cacattatca aataccacta ttgctgcatg tggattacca
    20641 gaaagaccaa ataatagctt ttctcccaat atacctacat aacaagctcc accaggttta
    20701 atgtttatct tccaaaataa ttctgttgcc cctatttttt tgaatacatc tggaattaaa
    20761 tctttatctc caacagaaac accacctgtt gtaattaaaa aatctacact ctgtaacata
    20821 ttctttacct ttttttctaa ctccaatata tcatcagaac aattgcatat tgtatctgcc
    20881 tgtattccaa gttttaataa tcttgaatat aaggtatatc tattactatc gtatatttta
    20941 ccattctcta aagtctcatt tatatcttgt agttctgtac ctgtattcaa aattccaact
    21001 tttaaatcat cataaacagt tactttggat attccaagac ttgctaatac tccaatacca
    21061 tcatatccta tattctgatt tttattaata atcaattgcc ccttttttat atcctcaccc
    21121 ttaaatatgt aattatcgta ttcctttaat tttacattta aaattatcat atcacctata
    21181 accgttacat cttctttttt tattacacag tttgcaccct gtggtatctt tccaccagtc
    21241 attatcttca ctgcttcatt tttatttaat accttattaa atacttctcc tgcatacaaa
    21301 gtccctataa cctttaaatt tctattttca gaatttgcat tatatgcata accatcatag
    21361 ggtgacctat caaatggagg actatcaatt gttgaatata tatcttctgc aactacttta
    21421 tttactgcat ctataagatt tactatcttg accctgttta ttggtaaaac atttttttca
    21481 ataattttta tggcatcttc taattctatc attttaaata ctccccaata tattttttat
    21541 ttaagatatt tctatgtaat atattataga ttataaaagt tggaaatact tttatcttat
    21601 atttaattat aactaatagt tatctataag tgcagttcaa attttataaa tctaataaaa
    21661 aaactgttcc cagctagaaa tttccttcta tcttgaaaca gcatcatatg ctttagaata
    21721 ttttattcta ataaagttcc ttttattatt tttacaattt tatcactttc aatagttttt
    21781 atagatttta ttttgttatc cacaatactt attgtaagta cctctttttt taatattttg
    21841 ttatcttctt tcaatctata actcttaact actttactac cttcatgatt atatgctgtt
    21901 aaatcataat tcgcatctcc tacaatttca tttattctag actcttcaac accaacatac
    21961 tctcccaggt caatacgtct aaaattttct agtgatacag ccgatttttc atggtcactt
    22021 ttttcaatca caacactaga ttcagcatca atgactgata taccttgtga tgagaaagaa
    22081 ttggtttcaa cattgacaac tttattttcg ttaatatcaa catataaagc acttccatct
    22141 agttcatcat ttccagtata ttttggataa actaatgtca tataacttga tgtatttata
    22201 tcttgcattg tattcgattc ttttaaaact ttaggtttta tataataaaa tgtattataa
    22261 ggtataccca tattctttat aatgtactta taatctttat tcataatttc attaacatca
    22321 ttttgaactt ttgtcatagt tttttgctgt gttgctttac ttgctacttg atttttctct
    22381 ttagtatttt ctttatgaca tccaacaagt ataataccta aaatagttac acaaactaat
    22441 gaccttttta acttcataaa tcaatcctcc tttcttaaat tttatagtat ttatctatat
    22501 ctcaatttac agttatctct tttttcaata attatattta ttatattata aaataattat
    22561 ataatattta tttgaattta ataagattaa gaagctaatt gtaatttttc tgtaataaaa
    22621 aacactttaa agttgaattt tgaaaattca atttacgata tttttattgt aagtacctta
    22681 caatattata ccaaattatt cctaaacaat caaaaactcc atgaatattt aaaggttttc
    22741 tattttaaaa atcacctttg actattaatt tatcaaatat gttataatag ttttagataa
    22801 tttaaggagg attaaataat ggattttaaa caacttgaag tatttgttgc tgttgcaaaa
    22861 catcagagtt tttcaaaggc cgcaagagaa ctttttttaa ctcaacctac tgtaagtgca
    22921 cacatacaga atttagagag agagttggaa actgttctta taaatagaag caacaaagtt
    22981 attacactca caaaatctgg tgaaattctt tatgaacatg ctatatatat attgaataat
    23041 tgcaaacgtg caatttatga tataaaagaa tattcaggaa aaatagaagg tattatagat
    23101 atagcatgta gttccatacc tgaaacttat attttacctg attttatgaa gagtttttct
    23161 atgagttatc cagatgtaaa attttccata agccattatg attctcaata tgctatatca
    23221 gaaattttaa atgaacgaat aagctttgga ttagttggtt ctaaaatcaa taatcctcaa
    23281 atagagtacc tagacttatt agatgatgaa cttgttctta tcactccttc agattttaaa
    23341 attgataata aaaataattg tatcgatata ggagaattgg cttatctaaa ttttattatg
    23401 agaaaagaag ggtcaggtac aagaaactta atactaaaca cacttagtaa aaataacttt
    23461 ccagtaagta aattaaatgt aatagctcat gtagaatcaa atgaggctat taaggaaatg
    23521 gttagattag gtcttggagt ctcctttata tcgtacattt cagctattga ttatctcaat
    23581 gcaggtaaaa taaaatgtta taaaataaag ggtgttgatt ttactagaaa atttttcttt
    23641 atttactcta aaaagaaaac tttttcccca ttagaagata aatttctaaa cagattatgt
    23701 gagtatttcg aaattataat ataataactt taataaagta gtgcttaatt ttgggtttat
    23761 aactaattaa taagctaatt ataactatca cataaatgct tataaattat tatgaaccat
    23821 ctttcttttt tatttaattt agtcaaaaaa tccctcgttc aaatgaactt gggatttttt
    23881 tatttatact attccaatag cagctaatac tatacaaata atcataactg aaattaatat
    23941 cgtagttgtc tttacctttt ttcctaataa ccaatacata ataccgaata tcatagctgg
    24001 aagcatacat ggcattattt ggtctaagta agtttgaata ggctctgccc attctccact
    24061 acctacatta acactaagtt ttaacattac attagatgca gtcatacctc caattaccat
    24121 aagccctaac attgaagctg cttccataac ttttgaaact atacttgaac tactcacatc
    24181 tttaaagaat tgagttccat acttaaatcc tttatctaga catatatagc gtataataaa
    24241 atgaggaaca tttattatta aaaggaataa aatcggtccc attatgttac cctgagaagc
    24301 taaagctata ccaactccag ctgctataag ctttaatgtt ccccagaaaa atgaatctcc
    24361 tatcccagaa actggaccca ttaaacttga tttaacagca tttatactat tagcatcaaa
    24421 ttctttattc tttgcatttt cttcttccat agctccagat atacctacca aaagagtact
    24481 tatatgagga gtaactgaca taaattctaa atgtcttttt aaagccttag atttcttttc
    24541 cttatcatct ttatacaatc tacggattat tggtgccatc atgtatgcat atgctatatt
    24601 ttgcatacgt tcgtagttcc aagatgaatc taatgtcaat gaccttctaa agcatttcca
    24661 aaagtctttc ctcgttattt tactatcggg tgaaattgta tctaacttct tagaactcgt
    24721 tgtcatctac tattacctcc ttctctccta caaagttaac atatattaaa gctattgcta
    24781 atccaaacaa tgcaactcct gttactgtta tgtttaggta agcaaccaat ataaatccta
    24841 ataataaaaa tgctactgtt ttcttattaa gcatcatcct agctaacatg gcaaaaccta
    24901 ttgctggaat cacgcctgct gcaacatcca ttccatgagt tacatatgat ggtataaatg
    24961 aaagtatttt ttctattact ggaacaccta atgaaaatcc tatacctact attattgcta
    25021 atattaattt atttcctata ccaaataata attgcacacg ttctacgcct tcaatattcc
    25081 cctcttctgc ataacggtca gcaatatgag ctccccatgt aagtactact gtcattaaga
    25141 agttatctat aagcaatact agagttgcta taggaactgc aagtacaact gctgctgata
    25201 catcttgacc cgttaatatt acaaacgctg tggcaataat agaaccagac acaaaatcag
    25261 gaggattact tgccccaaca ggaaatgcac ccataaatac taattctaat gttgaaccta
    25321 ttactatacc tgtatgaaga ttacctagtg ctaaaccaac aagtggtgca acaactatag
    25381 gtctattatg cattgtagaa cctacaaaac tatgcatata tgcaaagaat gcaattagag
    25441 ttatcaaaat aacttgtgta aattccattt tcatccccct aaaattatat taatttcatt
    25501 acatttgtag catcatcatc aggaactaat tgtacaaata catttacgcc ttctgaatct
    25561 aactctttaa tcatctttat atcatctttt gatacatgca ctgctttaga tatattttca
    25621 cgattatcat ctgattttgt tccaccaagg tttatagatt taatagcttt tacctcttta
    25681 gcaagtctat aaacatcttc tacagattca caaagtatca ataagttata tttatcagta
    25741 acacctgagt taagtgcttt tatagaatct gctatgcttt tcattactaa cttaacatta
    25801 gatggtttag ccattttaag ccctgccatt cttaattcat cttttaataa ttcatcactt
    25861 gctatcaata tacagtctgt gcttaaaaac tttgtccatg taaatgctac ttgtccatgt
    25921 ataagtctgt ggtctactct tactaattta atcattataa ttcctcccta atttttttga
    25981 tttcatccat gaatgttttt acgtgttcta cactaacatt cccaaaatct ttgtaattat
    26041 ctttaaagta acttcctatt attgccatat ctcctaattc aagctgtttt tttgcatttt
    26101 ctaatgtaac tccagcagct ataaccaatg gaaagtctcc taaattttta cgaaacagtt
    26161 ctattttttc cattgatgtt tcttgacctg tagcattttc tgtaactgct atagcatcac
    26221 atcttgtcat tcctattttt aaatcttctt caacgtcatt ttctgataat actggctgat
    26281 atttaaaacg tacgcctcca attaaatacg ctgggcattt tgaacgttgt aatttaaaaa
    26341 attcttctaa agtagcttcg tctctaggtt taacatgacc tactacagaa tcaacctgta
    26401 tataactagc attatatttt gttgccagtt caaatcccat agtatcaaca tttaaacaat
    26461 ttactccata tggtattgac aaattagctt ttgatacata ttcaagtatt ctttctaaat
    26521 cataataatt accatagtaa ttttctaaca ttattccatc tacaccattt tcttcaaaga
    26581 ttgtaatctc ttttttagct ctttcaaaga tatcttctgg agtatctcct tttaagtgta
    26641 tcattgctat aattggtttt ttacttttaa atactgataa tattcccttt tttttcataa
    26701 actaaaatac ctcttcttct tctttaattt gtaatgtcac gctttgtatt cctcttctag
    26761 attcttccac taattgttct atatcttcaa ctgttaattc atcagaaaac cttgtaagaa
    26821 gttctaatac catattcaaa ttcattccag aaaataactt aacattatgt agattagtta
    26881 atcttaacat tgctgtacat acacttgctc catataagtc agataaaatt atatattcac
    26941 attctatatc ttctgatatt gttttttcta attctaaagc aaaatctgaa gcactttgtc
    27001 cagggtacaa accatacgaa ctaacacaat ctgctaaatc tcctactatc atttttactg
    27061 catttaaaag cccttttgaa aaatctccat gagatgctaa tattatcttt ttcatacttc
    27121 atcctcctac taaatataga ttatatttct gctgatactg catatttgta cttatcactt
    27181 cttataaatt gctcattgta atataagaca tcattatttt ctgtatacac cgattgtctt
    27241 actttcaata gtggcatatt acttgcacat ttaagatagt cagaatattc tttgtttgaa
    27301 tgttttactt caaatatatt ttctactcgt ttaggtaatg tgcttatatt attagatata
    27361 acctccatta aagatttatc ttctaattct tcttttaata aaaacatgta atctattcta
    27421 aaatagtcaa cttcaaaaat aacaggtact tcatctatta atctaagtct tttaatacat
    27481 attaccttct cttctagttc aatacttaaa gcttcagcta cttgcttatc tgcttttttt
    27541 attaaaacag agattatttt ggtacttggt tttgcattaa tacgatgaca agaattagta
    27601 aaactatttc ctgcacatgt tgcttctatt ctctctggta ttgttacata agtcccttta
    27661 ccacgttttt tacataatat atcttctttt acaagttcat taagtgcatt tctcacagtt
    27721 atacgactta tattaaattc tttacataag tctccttcag atggaagttt atctcctggt
    27781 ttatatatgc cagatgctat ttgttttttt atgttgtcat atagttgttg atataaagga
    27841 acaaaggaat ttacttctaa atccatttct tttttttgtc tcttttcatc cattttgctc
    27901 acctccctat gtaacatttt tataacatta tataacaagt tctttattac atattataac
    27961 aagatgaaat cgttgtcaat ttttttttaa ataattttta atttgacagt attttctttt
    28021 attttctcta gtgtgacaaa ttgctatttt tacataaaaa taagactgtt gtacaacaga
    28081 ttaaattgtt tatacaacag cctttattca cttattacat ttatattttt acttataaat
    28141 ttatattaaa aaatgcctta tatcccttat acatttcata tatgtctact ttagagacaa
    28201 tctcatgtgg tgcatgcata tttaaaactc caacaccaca gtctataacc tctgcacctt
    28261 gatttgccaa tatatgggct atagttccgc ctcctccttg gtctactttt ccaagttcag
    28321 cagtttgcca tactacattt cctttattaa aaattctctt tacttctgac ataaattcag
    28381 cattagcatc attacatcca ctctttcctc ttgaacctgt atacttagtt aaaactactc
    28441 catttcccat atatgctgaa tttctctttt catatgcttc tccaaaattt gggtcatatc
    28501 cagcagaaac atcagctgat aataccttac tatttgctaa agctcttctt actttaatat
    28561 cacaataatc tccttctaaa gcaatcagtt cagccacagt attttcaaaa aactttgagt
    28621 gcatacctgt attcccttta gaaccaattt cttctttatc tacacataat gcaactgaag
    28681 taaattctgg ttgttcagtt tctagtatag cttttacagc agcatatgaa cataccctat
    28741 catcatgccc atatcccaac accatagacc tatcaaaccc taaatctcta gccttaccag
    28801 ctggaactac ttcaatttca gcacttaata agtcttcttc aactatattg tatttctcat
    28861 ttaaaatctt taatatattt gctgttatag gttctttttc ttcatcttct aaaggaatat
    28921 tcccaattaa tatatttaaa gcttctccac taattccttc tgatagtttc ttttgcattt
    28981 ggtctccagc caaatgaatc aataaatcag ttacacaaaa tactgggtca ctatcttctt
    29041 ccccaataga tatgtccact tttgttccat catttaatat aactatacca tgtaaagcaa
    29101 gtggaagagc tgtccactgg tattttttta ttccaccata ataatgagtc ttaaaaaaac
    29161 ctagattact ctcttgatac agtggatttg gttttaaatc taatcttggt gaatctatat
    29221 ggcttcctat aatcttcata cctttttcta tataattttt acctattaca aaaagtgcta
    29281 ctgccttctc tttatttata acataaatct tatcaccaca acttatgctt cctttttcca
    29341 tagcttcatc tattgaaata tagttatttt ctttagccaa ttttataatt tcttttactg
    29401 aaagtctttc agtctttgac ttacttaaaa actccatata attgcgagaa tattgcataa
    29461 tttgttcaat agtattttct tttctttcaa aatcccaagc attcttaaat tcgtacttta
    29521 agttcatatt ttcctcctac taagttctaa tttttattgt ttttcatgta ttgctcatat
    29581 tcttctggtg aaactacttt gacactatct agtcttgatc taaagtgagc tctaaagttt
    29641 tctaaatatt ctttccttaa aatttctctt tctttgattt catcagcaga aaggattccc
    29701 tctttatttt tctttgctaa ttcattaatc ctatctaatt tcttcttgtc aaacattttt
    29761 tcctcctaaa aaacctctat ttatttaata aaataattta ttgcttttta tatctaactt
    29821 gtttttatat tcacaaaaaa actcatctat attatcactt attacagata ttcccttttc
    29881 tagttcttcc atgcttgggc gagctatatt tatcctaaag aatctatcat ccactagatt
    29941 gtcaaaaaaa taagttcctg gaagcattga cactcctttg tttaacataa aatttgtaaa
    30001 tgcttgagat gtatatcctc ttggtaattc taaaaaaaag tttattcctc cacaagattt
    30061 tctaactttt aatttaccac tcaatttgtc attaatcaag ttttttgaca atttatactt
    30121 attagtatat atcttctcta tatgactcaa ataattcttc caatcaaaat tattcatata
    30181 gtaatacatt gatttttgaa ttaaacctgg tgttgatata tctgatgaat atttagccca
    30241 taaaactttt tttaacaact catttggcat ttctacaatt cctatcctaa gacctggcat
    30301 aagtattttt gaaaagcttt ttatatatac tactctattt ttatcatcat aacttctaat
    30361 tgttctattg tcctttgatt caaaaacaaa atcacttata aaatcatctt ctattatata
    30421 aaaatcatgt tcttctgcca attctatcaa tttctttttt ttatatgttg agtaagatat
    30481 tccagttgga ttttgaaaat taggcataat gtatataagt cttggtttta ttttttccaa
    30541 ctttaatttt aaaataccta tatcaattcc atcatctaac ataggtatag atattatttt
    30601 tgcacctcta cttttaaaca cttcaattgc tccattgtaa gaaggttctt ccataaaaac
    30661 aacatctgaa taacttataa gtcctttaca aactatatct ataccttgtt gagcacctga
    30721 tattatttga atattttcct tagtagtttt tatatttcca tcacttagat actctaccat
    30781 tttttctctt aattcttcag agccaagacc ttcatcatat tcaaatattg aactaccatc
    30841 tttagataat gccatattta cagcattttt aaatgaatcg ataggaaaca tatcattaga
    30901 tggattccca ttgtcaaaat gaattaaatc ttctctttgc acaataatct tatttttcct
    30961 gttatctata ccgcttttat aagaatttga acttgataca aaagtaccac tccctataat
    31021 tttatataca tatccttcat tttctaaaag ctcgtatacc ttaactatag tagtgttatt
    31081 tacttgtaaa aaatttgata gttttcttat tggaggcaat ttttcatgtt ctactaactc
    31141 tttatttatt atcaattctt ttatatgatt aaatatctgt atatatttag ttgatttttt
    31201 ctcatttaaa tctattctgt atttttccaa atttatcacc gctcattgta tttatatttt
    31261 attgatgctt ttatatatat ttgatattat ttagtatgta tatataatac caaaattttt
    31321 ataaaaaggg gaaatattta tgttttacga ctatcacatg cactcaagtt tctctacaga
    31381 cggaaaatct acaatggaag aaatggtaaa aaaatctatt gaactcggtt tggaggaaat
    31441 ttgtttcaca gaccatgttg actatgatgt atatgctgat gattcttttt caattgtcta
    31501 cgaagattat tttaagagtt tagagactct tcaaagcaaa tacaaagata aaatatcaat
    31561 aaaaaaagga attgaatttg gagttcaaac tcaattaatg gatacataca aaaaggaagc
    31621 acatcaatat ccattggact ttataatatg ttctatccat gctatagata caatggactt
    31681 ataccttggt aattatttta aagataaaac tcaatatgaa gtttatgaaa attactatct
    31741 ttatttatat aatattgtta agaattataa agattactct gtcttaggtc atttagattt
    31801 gattaaaagg tatgcacctt atgacactat tttagatgat agactatttt ctgatataat
    31861 tgaagaaact cttaaacaag ctatttatga tggcaaaggt atcgagataa atacctcttg
    31921 ttatagatat aatcttccag acctaacccc atctaagtat atacttcaaa tgtacaaaga
    31981 cttgggaggg gaaatcataa ccacaggttc agattcacat catataagtc aagttgcatg
    32041 tgagtttgac tacatatatt cattactaaa aaatatggga tttaaatatg tatctaaatt
    32101 taataaattg aaaccagaat ttataaaatt ataaattttt acacctcctt gtgaatatat
    32161 ttaaaagata aggaggtgat ttttttgaaa gtaccttatt tagtactatc aacagttatt
    32221 ttatttatat ccaattttat tgtaagaata tttggttttt tatataaaat attcttatca
    32281 agagcactag gtgaaacagg tttaggtatc tatcatatga tttttaactt tttgatgatt
    32341 tgcttagctg ttacaacaac aggtatacct actgcactta gttgtctagt tgcaaagaga
    32401 aaagctttaa acgatagaca caatactaat gctctattta tatcaacttt atatatatca
    32461 tttttcgtag cactaattat atctatagtt gcatctttca atagttcttt tttatcactt
    32521 aaatttttaa aagatgctaa attaaatcta tttatactag ctgtttgtcc tgctatagtt
    32581 ataataactc tttcaaacgt actaagagga tattactatg gcataaagaa tgtaaaaatc
    32641 cctgctattg gacaaatcat tgaacaaatt ggtaaaatat tatttgtttt tttacttgtt
    32701 atgtacataa ataataaatc tatgaattgt tatatagctc tattaggtat atctattggt
    32761 gagttgagca atattatatt tatgcttatt tgcttatggc gagattcatc atttgacaat
    32821 aggtatatta taagcataaa agatttttat aattcttcta tggaaacatt aaaaatgtct
    32881 attcccataa cttgtaatag aatgtcaaac atacttttgc aatctataag ttctatgatg
    32941 ataccatcaa gattagcatt atcaggaatg acttatcaac aatctttaag tatgtatggt
    33001 attgtcagtg ggatggtaat gccctttata tttttacctt ttactgttgg ttcagcgctt
    33061 attgtaaatt taataccaac tatttcacag gaaatggctc taagaaagcg taagagtgta
    33121 attaaaaaaa tcaaatactc catacttctt actttatttg taggcatact atcatcaata
    33181 tttttttatt tctttggaaa agatttatgt atattagtat ttaaaaatac acttgcagga
    33241 gaatatctaa aagctatgtt tttagttcca ctatttatgt ccctaaatca aactctatct
    33301 ggcattttac attcaataag aaaagaatta gcttcaagta taaatactat tactggcatg
    33361 ttaattcaac taatagcttt atatgtattt cttccaattc caggacttaa tatttatgca
    33421 tacatataca caatgacgat agtatcaatc tttacttgtc tattacatac tatagtgctt
    33481 tttaaatcac taaaatctat acgctagtta taaaaacgtg aaggctacca atgtaaatta
    33541 tacactttgg tagccttcct tagatgattt ttatttataa tttaaactgt ctatatatct
    33601 tacctatcta tctgtggcaa cttggctttc cacttccatg attaggtcca cattgcgaaa
    33661 aatcacatac tttagagaaa gtatcaacaa gtcttggttg gattggattt ggtgatgcta
    33721 aaactactat ttgttcactt attaatgtgc taactgtttc ttgtaagcaa agtactaaat
    33781 ctatatcatt tggtataatt aattcataga aaggttcaca acattcgttg cattctaatt
    33841 ttaatataga ttttcctata caatctacag ttaagttagt ttgatattct tgtcttaaag
    33901 taacagctct tccgtcagct ggcaagcata ttggtgctga aagtgtgtta aaagtaaatt
    33961 ctacataatc aactcttctc ttacatccac ctcctgctct aactgctggg aaagctaatg
    34021 caacgaactc tgtacatcca catctacctc ttagctctag tactaaatta cgaactgcta
    34081 cagttaatcc tctttgttta taagctactg atttgccttt tccttgtcta cagcactcag
    34141 cgtttctttc tccacaaact gcaaattcaa aagttgtttc acagtttctt cctactatat
    34201 ctcctaatgg gtctaaatcg aaatcttcta aagttgtcat tcctgtgtct ataactattc
    34261 catcattact taagcatatt ttttctatag ttacacttgc ttgacctgca cttggaattg
    34321 aaccaaatac ttctactact tctgtttcaa aagttaatgg ttctccattt ggacctgttg
    34381 catctgtaaa tgtttggaat tgcatagtat caaatattct attagcctct attgcaaatg
    34441 gcactgcatt tgatacagag aagtttcttg gagatatcgg attacaacat tctggtccac
    34501 atttgttttc aaaacattca tctgaatcca tttcacatgg ttcacaatca catttacact
    34561 tgtcatggca ttcacatttg tcatcacatg gattaggttt gcatggattg catgggttag
    34621 gtttacatgg attacatggg ttacatggat tacactcatc atggcactca cacttattat
    34681 cagtattaca tccattatga tggtgtgatt ttttaaaccc tctcatgtct tctgaattta
    34741 tttcatctgt atacacttct tcttcattca ttgtagacat tggctgattc atcattcttc
    34801 ttttattttt tttataatct tgcatttttc attgccctcc ctgtaagcga ttcttattaa
    34861 gtctttggct ttttgaagcc taattaatac tatgctttta taatcttaat tgttacttgc
    34921 tttttgaatt tatcaataat taggcgtatt tagtagaaaa atgcatatta ataaaaaaag
    34981 tactactatt tgaaatagta gcactttttt tgtcccgaaa caccggtggc taagtaaatt
    35041 cacaccctag gcactcccag gtgggtgact tgccagtaac ctttaacgtc caaactaact
    35101 aggcatgtta taatttacca gacacggtct cccgtatttc atttgtaggt tgaatttaaa
    35161 aaagccttat cgtatgtttc aggatttcat attattatta tataataaat tttgaatttt
    35221 ttaaagtggt tttatatagt aattgagata atcttattct atcattactt tttcttcctt
    35281 ttttctttat gtatttagtt aattatcgtt ttttcttagc tctagtttta gtattttttt
    35341 cattataatt gtattcggat tcttgctcat taatgttgta tagttcctca tcgtatacta
    35401 tatcttcatc attttctata ttttcatagc ctgtgttctt atcttctact aattcatctt
    35461 cattatcctc catttcacct tcatctgtta actcatcatc atccaattct ttgtcttcac
    35521 aatctaattc ttcgtcttca taatttaact catcattatt gtcttcatca tcattattac
    35581 tatcatcacc tcttaaaaga cttcctaaca atttgagatt attcatacta ccaagattgt
    35641 ttatatttgc caaagagctc aaactaaatc caccttcacc aaagtcatct ggtaaaaata
    35701 attctgcaaa taaatctatc ttctttttca ttcctatagc tttttcaact gaattttttc
    35761 ttttttctgg gaatacatct ataatttcct ttatcatcat attcttttta tcatcactat
    35821 ccatttttct gaaaaaatcc gtttcatctt ctgtatctac catatctata ttatttaatt
    35881 tttttattcc tctaactaaa tctaaaacac tttctatttt tattagtatt tttctttcat
    35941 ctcttgacat gtatttttta gttcttgtta ttatttccat tcccatttct aaatcttctt
    36001 cacttaaatc catgagcctt aaacctcttt ttatatcatt tgcatcaaac cttaaattgc
    36061 catgtgtaga ctgtgaaagt ttatcatttg catttttttt gttttttcta actctattat
    36121 ttccttttga tttattttta tcatcaaata tagagatatt accattactc aatgcaatca
    36181 ctccaatcaa aaatagtaag ttattcaaga caattccccc ttatattata taattgccct
    36241 atattaaagt atgtttttca tattttaatg ttccattttt aaagctcagt gcatatatat
    36301 tatctataag aatttttatt tatattatat atcactcaca attcaccact tcaatattat
    36361 ttctatatat aaatagtatg aatataattc aatatatatt tatagaaagg ggttttttta
    36421 tgaaaaaatt agatacagag tcattagaaa aaatggctaa acaaaaaaat attgacaagg
    36481 ataaaataga aaagatggct gatagttaca aaggaaaatc agaaaatgaa cttatggagg
    36541 aacttataaa aataggtaag aacttagatg gaagagatga agtagtatca aaattcaaag
    36601 catttttaga tgaaaatcaa cgcaaaaaac tagataatat aatggaaaaa atctcagatg
    36661 cagaaaatca aagagatact aaaccagcta aaactaagaa ggctaaacct actaaaggta
    36721 aatcaaattc acctgcacca aaaaatacac caggtggtca acaaaaaaaa tctaaaggtt
    36781 tatttaagaa aactaaaaag tctaaccctc atgagtagat aaaaataaac tatttaagta
    36841 attagataat tatttttagt taatctatta ttaaatttga tattattgac ataaaaaatc
    36901 aggtagtgcc ttaggcacta cctgattgat tttaatagtt ttattttttt ctttctgtaa
    36961 cactttctct atcaacaatt ctataaggta attctatttt cttattttca attaattcct
    37021 tatttattaa ttttataacc attcttattg ctactgctcc catatcgtat agaggttgat
    37081 atactgtagt aagtttaggt ctatacattc tagctatctt aacatcatta aatcctgcaa
    37141 cagatatgtc ttctggaacc ttatatccag catcacatat agcatttata gcacctatgg
    37201 cagcctcatc acctgttaca aaagccgcat gaggtattat tccatcatct aatagttctt
    37261 tcatactatt gtatccactc tcataatcag ttccaccata cttaatcaaa ctcttgtcta
    37321 attctatatt gttatttgaa agtgctttct cataaccagc aagtctttcc atttctaaaa
    37381 cagtatcatc tttactcgtc attataaaag ctatcttttc atgacctttc tttataagat
    37441 gctctgtcat atcaaaagta gcttcttcgt tgctagtact tactgtatat atatcataat
    37501 ttctagcagt tttacttata tatgtcgctg gtattccaca attttgtata tagttgatat
    37561 gttcttgttc aactatccat gaaatcataa ctataccttc cacttgtttt gctctcaata
    37621 gatttatact cttaagttct tgttccttat cagagtatgt attcgctaaa agaatatcat
    37681 agtcatacat tttagcaact tcttctatcc catttaacac ctcattaaca aaagaatctg
    37741 aaacttctgg aactattacc cctattaatt gactcttctt tgttactaag cttctagcaa
    37801 gtggatttgg tatatatcca gtctctttta taacctctaa aactttttgt ttgacttcat
    37861 cagttacagg ttttgaatca tttataactc tagatacagt agatattgac actcctgctt
    37921 gtttagcaac atcttttatc gttatattgc ctttcatctt catcctcctt attttactaa
    37981 atttatctaa aactgaacca aatttttgaa ggttcctatt ttaactacat ttatataagt
    38041 ttttatttta ccataaaagc aagtacattt aaatacatta tattttatat tataccctat
    38101 attcaacaaa tttaataata ttcattctta atttaaatca tattaaaaaa taaaataaaa
    38161 aaatactggt ataaaatacc agcatttttt tattctaatg atttaagtat tagcagccgc
    38221 aacctacttc accatcaaag aatccaccac atgaacaagt tattagcaat aatattaaga
    38281 aaggtatcca tgacattatg tcaatgtctc tccagcaatc ttcaaaagct aagaatagga
    38341 agaatagtac tattatccac catcctcctc caccaaagca tccttcttct ccaaaaaatc
    38401 tatctaacat aacaaagccc tccttttttt aataactgtg ttcttattct aagcatccac
    38461 cacagcagca aagtattaat aaaactatta ggaatggtat ccatgccatt atgtcaaatt
    38521 ctgcccagct atctccaaaa gctaagaata ggaagaatag tactattatc caccatcctc
    38581 ctccaccaaa acatccttct tctccaaaga atctatctaa cattgtacgt tacctcctgt
    38641 tgatattttg ttgagctttt cgctcctaac atatactatg catttggttt ccattttgct
    38701 aatgtatttt tactattttt ttaaattttt taatttgaac taaaaaaggt aaaaccataa
    38761 cttgtataag ttactggttt tacctattta ataatcaata ttttttagca acaacaacca
    38821 tcatcgaagt taaataataa caatactatt aatataaccc atatccatat attgtcatcg
    38881 cataataagt cttctaaaat gtctgtgcat aatagtaaga atactataac tattattatc
    38941 aacattttat taccaaaaaa tccttcgcat cctccaaaga aacgttccat attgtcttct
    39001 aattttgtca taactaatcc tccttgaatc attaagagac taagttttgt ctctttaatt
    39061 aaatatatgt agtaatagac agataagtta cttctaaaaa gtttttattg attagtttat
    39121 ttatttcttt ttcaccaagt ttattgtatc tatcaacttc atccagataa tcttttttct
    39181 cctctgatat agtgtagatt aaactttcta ttgattttat tttgtactcc ttatatcttt
    39241 ctatcaagaa ggatgttttt gaattttcta ttcctttctt tacatgcatt aaccttgata
    39301 tgtagtcttc tttttcatta gatacataac tctccttttc agctacatct tcaaggatta
    39361 aattggtctc cattacataa tcctctatac gttgcatatc taaagttatt gaattataat
    39421 aaaaatttac tgctataagt aaaaacattc ctactgaagt tagtaatagt cctacatatt
    39481 tcatagcatt tcctcctaag ttatatttgt tatcaataaa gtttattcat caaataatac
    39541 tttattacta catttataaa attttattat tttttataga ttccatattg aaaaattctt
    39601 gatattatat taaactaaca ttaaaattaa ttaaaactgc tttaggaggc ttaaaatgtt
    39661 tgagaaaata aaagaaataa tagcagaaca attaggggta gacaatttag atgagataac
    39721 tatggaagca tctttaatgg acgacttaga agctgattca ttagatgctg ttgaaattat
    39781 aatggccctt gaagatgaat ttggaataga aataccagac gaggaagctg agaactttaa
    39841 atgtattggt gatatatgta aatatatcga agaaaacaaa tagtatcgtt ttgtctacaa
    39901 atataaatag tctgtgtaaa cttctacata ataaattata ttagagttcg cacagactag
    39961 attacattta tttacaatat ataaaataca cgctcttata tttaatttat atactaagta
    40021 tataaattac ttttcttcat aaaatgtaac attctttatt attatatcta tagttccatc
    40081 ttgattttgc tttacagtat acttcattgg gtcttcaaaa tcagttagat tcccttttat
    40141 gtcaaaacca ttatccgttt ttatacttct ttttttaagc tttttctcaa cccatttttt
    40201 atctatacta aaactttcat caagaccttt ttcttccata tgctctttaa agctatcctt
    40261 taactcatca tctttaattg aattatcaac aaagtcattt atatcaactt catgtttttc
    40321 cttcagtgta taatttaata tacttcttac atcttcagct tgctttatat cattactaag
    40381 agcattagtt atccaatttt cagctgtatt tttaaatacc ttggtcttgt acttatcatc
    40441 atctattttt ttagcattta aaaattctgt tacaaactta gattctgacc cttctttttc
    40501 agcatcctta tctaaaagcc ttagatgaaa ctcatcattt ataccactta aactaatcaa
    40561 agctccttgc ttttgtctta aagtctctgg gataccaatt tcatttgaaa ccatttgaat
    40621 attaaattta tcatccacaa attcaattga atgagtgtac aactttttat aatctaattt
    40681 cagtattgct acactctttt catctttaat agtgtataag caaattgcca aatcacaaga
    40741 ttctagtgca gcattaattt tcataacgtc aaacaagtaa gatgcaattt ctttagaatt
    40801 tttcaaaaaa gtactttcat catatattat ttgttcacaa cagtttttaa ttaaattgtc
    40861 attataatct ttaaaaacac cttttcttaa atcctcatct tttgcaattc tttttatagc
    40921 tttctggaaa aaaccatcta cttcttgatt aactttgcct tcaaagtcat ttaatattgg
    40981 aacatcacta tttttgtcca aaacatgtat tataaattta tgtattatca tatatatcac
    41041 cccattatct taatttcgat attaactctt tcatatcctc tggtatatct gctttaaatt
    41101 tcaatttttc ttttgttctt ggttgttcaa actctagctt gtatgcatga agtgcttgcc
    41161 tatttattag ctcttcatct acataaccat acaactcatc acctattatt ccatgaccta
    41221 tatgagccat atgtactctt atttgatgtg ttctaccagt ttctaagctt acttctaata
    41281 cagttgcatt ttctagtctt tctattactt tatagtgagt aacagatgac tgtcctcttt
    41341 catctattat cctctttatt gaatcttctg taggtctata aattggctca tctatagttc
    41401 cctcattttc ttttataatt ccatcaacta ctgttatata ctttttttca actttatttt
    41461 cactcattgc tgtagataaa gtatgatgtg cataagcatt ttttgctact ataactaacc
    41521 ctgaagtatt catatctaac ctatttacaa atcttatttt tacgttttct ttttgattat
    41581 ctatatagta actaatacca tttgctattg ttttatcata gtggcttttt gttgggtgaa
    41641 ctaccataaa tggaggttta ttcaccataa ttatatcaaa atcatcataa attatctgta
    41701 aatttaaatc ttgaggttca aaatttgctt tttcctcgtc tatttttact tctattaaat
    41761 caccactata cacctttaaa cttggttttt tatatactcc atttactaaa acactctttt
    41821 ccttcttcat ttttgataat gacctaactg agaaatttag cttgtccaat aaaacttctt
    41881 ttaaagtcat ttcttcttca tttgtatacg atataagatt atatctttga ttctcttttt
    41941 taaacaaact tttacctact ttcttttata tcttcctgct ttttatatct tcaaaatcat
    42001 gatattatat attttacact atttttgttt aatagataat aattattttt aactataaaa
    42061 acctgtaaga ataacaaata gttattcata caggttaaat tcataattaa atatttaatt
    42121 tgtaaatatt ataatctaaa actatctctt aactattaaa gtagttccca ttccaccacc
    42181 tatacaaagt gtagcaagac cagttttagc atctcttctc ttcatttcat ataaaagtgt
    42241 agtaagtatt cttgctcctg agcatcctat tggatgtcct atagctattg ctccaccatt
    42301 aacattaact ttattcatat ctatatttaa gtctcttatt acagctacag attgggcagc
    42361 aaatgcctca ttagcttcaa ctaaatctat atcttcaata gtcatattag cagcttctaa
    42421 agctttttta gttgctggaa ctggtccata tcccattatt ttagggtcaa caccagctgt
    42481 tccataagaa actatagttg caagaggctc tattcctagt tcttcagctt tttctttagc
    42541 cattactact agcatagcag caccatcatt tattcctgat gcattaccag cagtaactgt
    42601 tccatctttt ttaaatgcag gtcttaactt agcaagtttt tccattgtag tgccaggctt
    42661 aatatattca tctttatcta ctacagtgtc accttttctt ccttttataa caacaggaac
    42721 tatttcttca tcaaattttc cttcagcttg agctttttca gctttatttt gacttgcaag
    42781 agctaattca tcttgttctt ctctagttat attccattgc tctgctatgt tttcagcagt
    42841 aatacccatg tgatagttat taaatatgtc tgataatcca tcttttatca ttgaatcaac
    42901 aaaagcagca tcacccattc ttgcaccata tctcgcactt ggtactaaat aaggagacat
    42961 actcatattt tcagctccac caactaacat tatatcagca tcacctaatg ctataagttg
    43021 agatgccatt gaaacagatc ttaatccaga accacaaact atatttatag tcatagctgg
    43081 tttttctact ggtattcctg ctcctaatgc tatttgtctt gctatatttt gtccaagacc
    43141 tgctgtaagt actcccccta aaagagattc atctatcata tctggagtta tgttagctct
    43201 ttttatagct tctttagctg ctgttacccc taactctacc gctgaaactg atttaaatgc
    43261 tcctccaaaa cttcctactg ctgttctagc tgcactggca attactactt ctctcatatt
    43321 cattaccccc attaaattag atttttcata tatccgaaat tgttttttaa acaattttat
    43381 ttaaactttt aattcccaaa ttcttattta ttataatcat agaatcctat cttagttttt
    43441 cttcctaatt gattagctct aaccatttta gctaaaagtg gatgaggtct atatttagta
    43501 tctccaaatt cagtatataa aacgttcatt atagctaaaa caacatctaa tccgattaaa
    43561 tcacctaatg ctagtggtcc cattggatgg tttgctccta atttcatagc ttcatctatt
    43621 tcttctttac ttgcaacacc atctgcatat ataccaacag cttcatttat cataggtata
    43681 agtattctat ttactacaaa tccaggagat tcagatacat ctactggtac tttattgata
    43741 ctcttagata attcaaatac tgtatcaaaa gtaacttttg atgttaactg accacttata
    43801 acttcaacta atttcatcat aggaactgga ttaaagaaat gcattcctat aactttatct
    43861 ggtctcttag tagaagaagc tatttctgtt atagataatg atgaagtatt tgttgccaag
    43921 atagtatctt ctttacataa ttcatctagt aacttgaaaa catctttctt tatattcatg
    43981 tcttctacag atgcttctat tattaaatcc atatctttta aatcttcata attagtagtt
    44041 gaactaacat gacttaatat ttctgctttt gtagcttcat ccatttttcc cttagtaact
    44101 aacttagtta aatttttatc taataaagct aaacatttat ctatagcacc ttgagttcta
    44161 ctctttaaac atacatcatg tccacaactt gcaaaagttt gtacaatacc acttcccata
    44221 gttccactac ctattacagc taatttcata gttataacct cctgttattt tagtatttat
    44281 attctgttaa ctagattaaa atactattta atctagttaa cagcaaatat atttttaatt
    44341 agatttttac ccttttataa agttagcttc tctcttttca acgaaagctg acattccttc
    44401 tttttggtct ttagttgaaa aacaaagacc aaataaatta gattctatat ctattccagt
    44461 atttatatca gtttgagcac caagttgtat tgcttcttta gagtatctaa ctgcaagctg
    44521 agcattttta gctattatct tagctaattt ctcaacttct tctattaaaa tgtctggctc
    44581 aacgactcta tttactagcc ctattttttc agcttcatca gcttttataa cttgacctgt
    44641 aaagattaat tcttttgctt ttgccattcc aaccaatctt gtaagtcttt gagttcctcc
    44701 atatcctgga gttattccaa gagttacttc tggctgacca aatttagctt tagcagatgc
    44761 aattcttata tcacatgcca ttgcaagttc acatcctcca cctaaagcaa atccgtttac
    44821 agcagctatc actacttttt tactattttc tatttctcca aaagcttttg ctcctaagat
    44881 actaaaatct ttagcagcta cagcatctaa atctttcatg tatgcaatat ctgctccagc
    44941 tacaaatgcc tttccttccc ctgtcaatat tacaacatca atagtttcat cattattaat
    45001 atctacaaat acttcataaa gttcttctaa agtctttgaa tttattgcat taagggcttt
    45061 aggtctattc attttcactg tacatatatt tccatctact tcaacagcta cattctcata
    45121 aactttaaca tcacttgtac tcataatacc ctccccaaga aattagttag ctaaaacttc
    45181 acctttttct tttgcaacac ttaactgact gataagttct ggaagcactt tatgaacatc
    45241 tccaactata ccaacatcag catatttaaa tattggagct tctggatttt tatttatagc
    45301 aactataaac tcagcatctt ccataccagc tatatgttgt attgctccag atataccaca
    45361 tgctatataa aggtctggtc ttacagtttt accagtttga ccaacttgtc ttgctttatc
    45421 taaccaacct gcatctatag tggcacgaga accagaaact tctccaccta taatttcagc
    45481 taattcataa agtatgtcta agttttcttt tccacccatt ccacgtccag cagaaactaa
    45541 tatcttagca tcttctattt taacttgttt tttagcttct tttattactt gtacaacttg
    45601 aactaattta tcagcatcat taaattctac cttgaaacgg ttaattacag cttctttagt
    45661 ttcatcaggt tcatttttct tcataacccc tggtctaact gtagacattt gaggtctgaa
    45721 atctttacaa actattgttg ccattatatt tccaccaaag gcaggtcttg tcattaataa
    45781 taattttgta tcttcagcta ctgcaagacc tgtacagtca gcagtaagac ctgtatgtat
    45841 tctagcagaa actctaggcg ctaaatctct acctattgaa gttgcaccaa ataatacaac
    45901 tatagggtca gctgctttta ttgcttcata agctgctttt gtatatggtt cagttgtata
    45961 cactgctaaa gcttcatcat ctactactat tacctcatct gcaccatagt gtgctaatgt
    46021 atctattaaa ccttctacct tactacctaa aagtaatgca gaaacttttg tatcataatc
    46081 ttttgctatt tctgtagcct ttcctagtaa ttctaaagaa acagtttgaa ttacattttc
    46141 tctttgttct attactacta aaacgttacc cattctttat ccccccttaa attatatgat
    46201 atacttctct tttaatttat ctatgataat tccagctgat gttttcgcat cttcattgta
    46261 tattgtacca gctggtttaa ctgattttgt aaatgattta aatacactag ttggagaacc
    46321 tttaagacct aaattagaag ggtcaacttc tatatctttt acagtccatg tttctactac
    46381 atcattttcg aaagcatcat atattcttcc aactttcatg tatcttggtg tgttcatatc
    46441 tttaagagtt gttataaggc atggcatttt aacttttaag tcatggcaac aatcttcaaa
    46501 ttgtcttttt actaatacat attcaccttc agtttttatt tcttcagcat atgttattga
    46561 tggaagattt aaatgttcag ctatttgagg tccaacttgt gcagtatctc catctatcgc
    46621 ctgtcttcca gctattataa tatcaaaatc tatatttttt aatgctcctg ctaatgctga
    46681 tgaagttgcc caagtatcag cacctgcaaa tgctctatct gttaataata tacctctatc
    46741 tgcacccatt gctaaagctt cttttaaagc catatctgct tgaggaggtc ccattgttat
    46801 aacagttaca tgagcaccca tttcttcttt taattttata gcttcttcta aacctgcttt
    46861 atcatcaggg tttattatac ttggtactcc atctctaatt aaagtacctg tattaggatc
    46921 tagtttaact tctgttgtat ctggaacttg ttttatacaa acgactatat tcataaatcc
    46981 ttcctccata tctattttaa tatcgaccta ttgtgtatat tttaatattt atctatttta
    47041 ataattttcc tgaaataacc attctttgaa cttcactagt tccttcatat atttcagtta
    47101 tcttagcatc tctcatcatt ctttctactg gatagtcacg agtgtatcca tatcctccat
    47161 gaagttgtac agctttcgta gtaacttcca tagctgtttc agctgcaaat aattttgcca
    47221 ttgctgcttc tactccataa ggttttccta agtctttatt tatagctgct tgatatacaa
    47281 ggtgtctagc cgcttgtact ttaacttcca tatcagctaa ttggaattgg gtattttgga
    47341 attttgataa tggtctacca aattgtactc tttcttttac atatttaaca gtttcatcaa
    47401 gagcaccttg tgctaaacct aaagcttgtg ctgctatacc aattctacca ccatcaagag
    47461 tagacattgc tatcttaaat ccttgacctt cttttccaag taaattttct ttaggtattc
    47521 tgcaatcctc aaatattaat tcactagtag ctgaacctct tatacccatt ttcttttctt
    47581 taactccaaa gctaaaccca ggagttcctt tttcaactat aaatgctgat attcctttgt
    47641 tccccttaga tttatcagtc attgccatta ctacatatat gtcaccagct attgcatttg
    47701 ttataaatat ttttgagcca ttaagtatgt attcatcccc gtctaaaaca gcagttgttt
    47761 gttggccaga cgcatctgta ccagcattag gctcagtaag accaaatgct cctaatttat
    47821 ctccacttgc tagtggtttt aagaattttt gtttttgttc ttcattacca tattgatata
    47881 taggccatga gccaagagat gtatgagctg ataatataac tcctgtagta ccacaaactc
    47941 tagacaattc ttcaactgcc attatatatc ctacagtgtc tccaccttct ccaccatatt
    48001 cttttggata tggtataccc atcattcctg cttttgccat tttttccact gtttcataag
    48061 gaaatctttc ttcttcatca agttctgttg ctaaaggttt aacttcattt tcagcgaagc
    48121 ttacatatag ctctttaagc atctgatatt ttttagaatt taaatccata atagcctcct
    48181 cagtatttta taaatatttt attttcattt attaattaaa atctcggcaa catctataat
    48241 aaggtatttg aatatacgtc gagaaattta taaccttaat caaactacgc tctatattta
    48301 tatgtgatta tactaaccaa ttatgacatt aatttaatca taaattgtta atttaaaatc
    48361 aactatactt aaaaaaaatc tcgctttttg gaattttgtg aaatttcaag ttagaataag
    48421 atttctttca cactggtcac agataaaata atttgtttac gatatttata ttagggtata
    48481 ttaaacatta aatattgtct gtacatctgt tttttagcca tgtacagaag atttttatcg
    48541 tataaaaatt attttaatag agctaaataa tcgtattttt atctgactat tttttatttt
    48601 taaatatctt acatctataa tagtaacact caaaggataa tttttcaata atttctaatt
    48661 atttttttaa caatatttat tacatttttt ccactttttt gtcatttttt tattgtttcg
    48721 aaaaaaaatc agaatttttt aactttattt tggattatta gtttaaatta gattttcctc
    48781 ttagatttat aaatatttac acaaaaaact acctctgtat agattgtata cagaggtagt
    48841 tttttactaa ttcctactat agtttactat atttttttac caattcttac aaacatctac
    48901 ccatttttca ctcttagaaa acttctccat ttcttcacat gtaagttcta ttgcagagtt
    48961 actactgcca catgcaggaa atactgtatc aaatctcttc attgaatcat ctaaatagac
    49021 ttttatagaa ttttttaaac caaatggaca gactccacca atagcatgtc cagtaaactc
    49081 caagacttct tctggtgtca acattttagc cttacaatta aattcagcct tatacttctt
    49141 attatcaatc ttagcatcac cagctgtcac aattaaaatt gcatcatctc ctattttaaa
    49201 tgagagtgtc ttagctattc ttgctggaat aaccccagct gcttcagctg caagttccac
    49261 agtagcacta gattgttcaa attctaatat actgtcttcc ttgccaaatt gtttaaaata
    49321 ctctcttaca ttacttattg acattaaata cccctcctag tctgaatttt tataaatttc
    49381 atattattct taattatatc tataattgat ttatttttca aattattcca taatattagc
    49441 attccatgta tcattatttt ttccaactac tagataaagt ccttttgcca ttggaatatt
    49501 gacaatatat tctcctttat attctacact cataccagat tcattaaagt acctataatc
    49561 aaaatttagt ccttttggaa ttacaaaatc aacataacct tgattatttg gttttattcc
    49621 atatttcaga gtactttcag ttatagaatt tttttcatta aataaatcta catttacata
    49681 tgcagaacac ttattcattc cctttttatt ttccacacaa ttttcaaact tcattttagc
    49741 actgtttaat ttataactat atttactatt attgcttatt ttaaatctta caatagtacc
    49801 gatatctcta cttctcctgc tatcaaaatc aaaaacaatt tcctctaaat gatttatttc
    49861 ataatctttg acacttacca tatctctata tactaattta tttatagcta tgaatagtgt
    49921 aaaaatcccc aaaataaaaa atgaaacttt tataaacttc ttcattttta gtctccttat
    49981 attttgtgct attgtgctat aatattaatt aaaattttaa taattaaact tattcttttt
    50041 tgaaatctta atagaaaaat acattgatat tataaaaatt attattgtta aaaatgtcat
    50101 actatataaa tttatatact tagtattagc tatatcagtt acataatttg aaagatatac
    50161 tcctccaact ttactataat taaaatgctt tacttgatat acaatcatac taatcatctt
    50221 caaaagactt ccatatacaa agtaaattaa aatacttact ataaaaccac aaactttcat
    50281 ttttccatat ccaaacttaa aaattaaagg cagtaaaatc gtcaaaattg ctaaaaatat
    50341 atttacagaa aaaaatacat catttaaaac catatttcta aagaacacta gtgatgtcaa
    50401 tttacttagt aaggacacaa ttattgttac agaaattatt agtcctacac ctaataaata
    50461 ttttgagtaa actatatctt ctatactaac tggcatactc cttataaaaa tccttgaatc
    50521 attttcataa tcacactcaa atgtatttat aaatatcaaa taactaacaa caatacttac
    50581 tgtataatat gaaattgaat taaggaaaaa ataaaacaca aaaaatagca atatgtactt
    50641 taaattacgg ataccatctg aactaattcc tattattaaa tcttttctta ttaaattgaa
    50701 catcctctca cctcatttac ataataatac attagttctt ctatagtagg atttttgacc
    50761 ttatgcttat caatttctat caataggctt tttactttca agctatctcc aactttaaca
    50821 agtgcctcat tataatattt atactcttta acaccaacta tactttcttt aattgcttct
    50881 aactctgctt tatttgccct aattatctta tattcttgtt ctattaattc tttcttaaca
    50941 gtaaaaatct gatttcctct atttataaaa acaagataat cagcaatttt aattaaatta
    51001 tcagtattat gagtagaaat tattacacta ctacttccat ttttcacaaa atcttgtaag
    51061 tactgcatta tttcagttct tacaatcggg tctataccag cagttggttc atccaaaatc
    51121 aataacttag cattatgact aagtgcgctt gataacataa gcttctcaga ttgaccttta
    51181 gataaatttt caatatgcat attttcttct atgtcaaact tattaaggta ttcatcaaat
    51241 ttttctctat caaaattctt ataaaataaa gaaactattt ttctaaattc cttaaccttt
    51301 aaatgtggat aaaattgtaa agaatcatat acaaaaccaa tattgttttt aaagcttatt
    51361 ggagaatttt caatagtttc attacaaagt tcaatttcac cttcatctgc atcaataatc
    51421 cccattataa tttttattaa agtcgttttt cccgaaccat ttggtcctat aatcccaaca
    51481 atatcccctt cctttaactc taagtttata ttatttaact tgaattttcc taattttttt
    51541 gtgatattcc ttatgctaaa cacatcttca cctcttatgc atttttttat acccacctat
    51601 acatatttta acacattcac tacaaaggtc atttataaat ttataaatta agaattataa
    51661 aactatgtta taatacaaag tatgaagagg tgaatatatg aaaagaatta taactataaa
    51721 tacaaaccaa ttaaataagt cccttgagac taaagaactc ttaactagaa aacttatcaa
    51781 tgctggcttt gaagtgtatt cagatattta tccagacaca gagcttatta tatcaattgg
    51841 tggtgatggc tcttttttaa gaacagttag agatttcgat tttcctgaga ttcccataat
    51901 gggaataaat acaggtcatc tggggttttt tcctgatatt ttaccagata agattgatag
    51961 ctttattgaa gcttatacaa aaaaagatta tattattcaa gaaatgtcac ttcttaatgc
    52021 ggaagtatat acaactacta gtggttctaa tatgcttgct gtaaatgagg ttgttataag
    52081 aggagacaag tctaggacta tacacctaaa tttaagcctt gataataaac atatacaaaa
    52141 ttttagtgga gatggtatga ttatttctac ttccacaggt tcaacagcct ataactattc
    52201 tgctggaggt agtattgttg atataaatct tgaacttatg cagattacac ctttacatcc
    52261 gataaatacc aatgcatata ggtgctttac atcaagtata atatgttcaa atgaatctgt
    52321 tataaagatt gcaccagaat atagatttga agattctgta ttgattgtcg ttgatggagt
    52381 tgagcacaga tttagacaaa tcgaaaatat aaaagttagt atatctgatg caaaaataaa
    52441 attacttaga atgtcaaact atgagttttg gcatagagta tctgaaaaat ttttatagac
    52501 tgtacttagg aggattttta atatgaaaat aggaataatg agtgatactc atggtagctt
    52561 actttacttt gaaaaagcgt taaatgtatt atctgattgt gatgttttat tacatggtgg
    52621 agatgtctta tatcatggac ctagaaatga tattccagaa ggatataatc ctaaaaaatt
    52681 tattgagaca ttaaataaat tagaaaacat tgtgattgta aaagggaact gtgatgcaga
    52741 tgttgaccag atggttatag aacatcctat tcagagtcct tatgtcatga gccaatttgg
    52801 tgaaattaga attatattga atcatggtta tatagaatca gaagaagaaa ttattgacaa
    52861 agcaaagaaa atgggtggtg acatattagt tttaggacat actcatgtaa aaaaactata
    52921 catggatgat aatttaatag taataaatcc aggaagtact tctatcccaa aagatggaag
    52981 ccattctgtc gcaattatag atatcataaa aactgatgat gaggatgagc ttgaacttga
    53041 tataaactta attgacatca atactggaaa tataataaat atcaatgatt agtaaatttt
    53101 taataaaaat aaaataagct ttaatttatt aaactcataa taaaaacaag taaaccattt
    53161 tatttctatc tcaattagaa gtttaagtac aataccttaa acttctaatt aaatagaatc
    53221 tggtttactt gttttattat atgctatatt gaaatataac ttagtttact tgtttctatt
    53281 atatattata ttggag
//
LOCUS       DAMJYN010000017        51771 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.017, whole genome shotgun sequence.
ACCESSION   DAMJYN010000017 DAMJYN010000000
VERSION     DAMJYN010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 51771)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51771)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51771
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.017"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            37..774
                     /gene="cas6"
                     /locus_tag="PC466_001136"
     CDS             37..774
                     /gene="cas6"
                     /locus_tag="PC466_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endoribonuclease Cas6"
                     /protein_id="HDF2768530.1"
                     /translation="MSRISIFMESCNGKFPNENSMLSVSFIKNILNAENKDFAKNIFN
                     YGEERKNNKQIKDINTAIYIPNLIRSKNELLVDGDIIFNISFYNYSMFSKLYNGILKV
                     KELEYKGYRFKIKNIKIHKEHEIKENGVIFKTMSPIIVKNKEGKYLDVEDSNYIECLN
                     YIANLTLESIRGSGLRKPLEFIPLNFKKRVLKEKIRGFKVREYYYINAYAGTFFLKGN
                     MEDLNALYKMGIGYRRTENAGMVDILK"
     gene            779..2254
                     /locus_tag="PC466_001137"
     CDS             779..2254
                     /locus_tag="PC466_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768531.1"
                     /translation="MREIKAKFYRSGDIVRDIGIVYFYELLMDLKNELEKNDYKLKFT
                     CELNRNYLSLESAEYIDPKYISDYILENQLFKVFKNGKKETLEKIFSNIDNLTYVNFI
                     EELDKSSATEKQKEGIKKDFKNRRFPYVRNSGKYGLNTSLENMETNVKRIVDTVIKSN
                     IEIDEIDKLDLTQYEEKDSVCNVCNINKTTKLDIDLRERKDSKYNFLFRGAEKSGFKR
                     SGQVESNICFECEFFNLMCLLYINLKRPMVFAYTNDLRELAFLNHKIMLKRKMYSDKS
                     FYKKLLHEKISSIRLYRFDIDTNKGIILKFDSIIEYKELLKKIELIDIIDNYNFSREP
                     GNTRNLGKKMIDNGNLSNLKELLLDNISVLRQLTGTSREMDFVSSSYNIGLYIKLCWI
                     VDGGEEYKMKNYMESNLIYSRVGKDLFNKMTDESRRKNFSMKVIQLLKSNDRTQLFQT
                     IMHVLVSNGILIGEGFVEGLMQSSELELNTNVGLFIQEIMK"
     gene            2274..3287
                     /locus_tag="PC466_001138"
     CDS             2274..3287
                     /locus_tag="PC466_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated protein
                     Cas7/Cst2/DevR"
                     /protein_id="HDF2768532.1"
                     /translation="MNEKRVKGVTLTILTESPVPLSYDQGYGNYTPIKKEQYREKIHA
                     KTSIATITYDLRRMLHQEYGWNLSNIIFGKKGNIYPSIKQNVGCVDENGLETDVFGYL
                     IPLKDKGSISKASPLRIIPFRSLNSYRGSTQLITNRGFLSSEFGRKYYDEKEENEVLR
                     DENFPTSQALAIEETLSDYYVYTITLELDRIGVVEVEDGKLLLPEERKFMSKELREKA
                     VKDILDAITVFTRNIKHSSVLLKPLAVMGGAFDKVVPFFWDDVDYNADSGEINLEGVI
                     ETIESYSLKESNTILAINDKLKISNKKELNKFNLSKYPVKEIKNLADRLEIGEDNMWY
                     LKE"
     gene            3303..4109
                     /gene="cas5"
                     /locus_tag="PC466_001139"
     CDS             3303..4109
                     /gene="cas5"
                     /locus_tag="PC466_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated protein Cas5"
                     /protein_id="HDF2768533.1"
                     /translation="MKVLQCKLKQPTAHYRDPKVFQNEYISTLNLPSKTTIMGMITYL
                     CDRRLNSDIDIGIIGTHHHRELEFSRGENIDFWNEYTNMRKGKDKEKFLLQGNYYDYY
                     KEHKAQNSILNYEVLKEVELTIFISCKDDEELEFIKKKLESPCKYANLGRKEDFVIPS
                     EKGCFVKEVELKEVMPMNTRDAIKENIKLKNTYVRVDLRDKENVETIINQGVLIALPY
                     KYKDLEANRDDRVYEFCHYIYVDNDGIYPKNIKVNVCNVCIDTKEVFTWL"
     gene            4136..6544
                     /locus_tag="PC466_001140"
     CDS             4136..6544
                     /locus_tag="PC466_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated helicase/endonuclease Cas3"
                     /protein_id="HDF2768534.1"
                     /translation="MKNIMQKEILAKSYNLRTNQQEQTLVEHIKDLFEVLESILELNL
                     YSDKDVEILKICCALHDLGKINSIMQQKMEINNKISYSCSEEERKKLESDKKSLKKIA
                     RHNIFSGAFLKDILEKMNLLEEDKLYIYKSIMLHHGNYEDYMRLSTSKVQEEIYDYIE
                     KGILEKEEFNLKDIESYINDILNVDFKFGEDVLDYDYIDKLSESMFIDSDYNNGQIDD
                     SVLNYRKFKYILYKGMLNLIDHSASSRQKGIKFYNDFTDEEIDDMILNEIYKSQGNLE
                     KNNIEFNTIQKRLRELSGRNVLTVAFTGSGKTAADYRKTFKRKFFLVPNKISAESFYR
                     KNIFQNKNDLDTRSSNDYIGLLHGDINLYSENEDNGEHDFVLTLRDIDLSINFCKPCV
                     IATVDQLLLSMFKFPGYEKIFAAVKNASITVDEVHLLEPKMFLILIYFMQFACKYLDV
                     DFHLMTATLPKSYKEQMINKGIIFQEESNENVTDKGEIVFIESNKEEEICEGKDVKVS
                     FIKEKEIKSIVEGALENKQKILIIKNTIDSVNRTYEFLKENLSDKYGGVDIDVLHSRF
                     KFKDKKEKYSKILNGEGDIWISTQSVEISLDLDFNIIISDLATMDSLIQRMGRCNRNN
                     KYEYGNFYILPSEDKIYDNKLKNTTKNILKDILKTNSIFTMGIRKTILDDYYDNSVVK
                     NYFEENFISCDKEIKNIYGINKEIFDGLDLIFNFEPYKNIVDSKKEAAKIFRDVDVSY
                     KIILEEDFYKEDRELQQDSIQVSGFIFNRLYYYGLISKVEGYMVLKSSSKFEYNSTVG
                     LILK"
     gene            6985..7932
                     /gene="prmA"
                     /locus_tag="PC466_001141"
     CDS             6985..7932
                     /gene="prmA"
                     /locus_tag="PC466_001141"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HDF2768535.1"
                     /translation="MNNWIEVTIKTTTEAVEPITNILYEQGAGGAVIEDPKDFLFQKK
                     NELDWDYVEEEVFKKNEEDDVLIKTYVSEEKNVMEFVEIIKQKVLGLKDFGIDIGEGS
                     VSLDQVNEADWANAWKAYYKPTKVGQRVVVKPTWEDYAMQDGDLIIELDPGMAFGTGT
                     HETTSMCIRELEKYVNKDSKVFDIGCGSGILAIAAAKLGAKEVVAVDLDEVAVKVAKE
                     NVLENKVEKSVSVMHGNLTDVIKDKADVIVANIIADIIKILAKDVQNFMKEDAIFISS
                     GIILDKVEEVKESLIENGFEIVEVQKLGEWSAIVSKLKK"
     gene            7951..8709
                     /locus_tag="PC466_001142"
     CDS             7951..8709
                     /locus_tag="PC466_001142"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HDF2768536.1"
                     /translation="MDRFFVEKNNINLQDKTCTIEGEDVKHISKVLRCKLGEKLEICD
                     KNNNEYICEIMNIDKSIVNLEILEKVDINRESELKVRLYQGLPKAPKMEMILQKLTEV
                     GVEEIILVQTKRSVVKVDDKKEDKKFERWERIIYEAAKQSKRGKIPKLRGVLSFKEAL
                     EDMKKNNVNICPYENERTVSIKHALKKCDSNIDSVGIFIGPEGGFSEEEIEQIQKNNC
                     NVVSLGPRILRTETASVVASTIALYELSDLGGEK"
     gene            8711..10009
                     /gene="mtaB"
                     /locus_tag="PC466_001143"
     CDS             8711..10009
                     /gene="mtaB"
                     /locus_tag="PC466_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-
                     methylthiotransferase MtaB"
                     /protein_id="HDF2768537.1"
                     /translation="MKKVAFYTLGCKVNQYETEAMLELFEKDGYEQVNSEEYADVYVI
                     NTCTVTHMSDRKSRQYIRRVKKKNPDAIIAVVGCYSQVSPEEILDIEEVNLVMGTNDR
                     RKIVEEIKKINSSKKVSTVDDIMKVKAFEEIEISQTNGKTRAFMKIQDGCDRFCTYCI
                     IPYARGRVRSRDIDSIVDEVKKLANNGYKEVVLTGIHVASYGKDLKDRDIKLLDVIKQ
                     INQIEKIERIRLSSVEPILFTDEFVNEVLKMDKVCPHYHLSLQSGCDETLKRMNRRYT
                     TLEYKTIVDRLRSKMPDVAITTDVIVGFPGETNEEFKKTYEFLKEIELSQMHIFKYSP
                     RKGTPAATMENQVDPQMKHFRSEQLLNLSKVNFNKFATKFIGRELDVLFEQNIEGNKY
                     EGLTSNYIRVVVESDKNIQGQILKVKINDVKDEYVEGILL"
     gene            10052..10402
                     /locus_tag="PC466_001144"
     CDS             10052..10402
                     /locus_tag="PC466_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine triad nucleotide-binding protein"
                     /protein_id="HDF2768538.1"
                     /translation="MDCIFCKIANGEIPSTKVYEDDRVLAFNDLNPVAPYHILVVPKK
                     HYDSLIDIPDKEMDIVSHIHVVINKIAKEKGFDQTGFRVINNCGSDGGQEVKHLHYHI
                     LAGKKLPNYEAGQN"
     gene            10565..10744
                     /locus_tag="PC466_001145"
     CDS             10565..10744
                     /locus_tag="PC466_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HDF2768539.1"
                     /translation="MSEVRVRENETLDSALRRFKRQCAMSGIMSEVRKREHYDKPSVK
                     RKKKAEAARRKNAKK"
     gene            10774..11217
                     /locus_tag="PC466_001146"
     CDS             10774..11217
                     /locus_tag="PC466_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HDF2768540.1"
                     /translation="MSLKQKLQEDLKSSMKNKDTVRKSVVTLIRASIKQYEVDNRVEL
                     DEDGIIDVIAKQLKQRRDALVEFEKAGREDLIKETEGEIEVLKEYLPQQLSEEELEEI
                     VKSTISEVGATSMKDMGKIMSVIQPKVKGRADGKLINKLVKQNLQ"
     gene            11328..11825
                     /locus_tag="PC466_001147"
     CDS             11328..11825
                     /locus_tag="PC466_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="HDF2768541.1"
                     /translation="MIISVKEIRNFLINIFIPLIIGYLSSILTMIISGTDISTYYLQL
                     TKPSFAPPAFIFPIVWTILYILMGISSYLILRKGYNLPKVRDAIFYYGLQLVLNFIWS
                     ILFFGFGLRFTALIDIIIMILVSIIMISKFSKIDKRSGYINLIYLMWLVYAGFLNYFI
                     WFINK"
     gene            12018..12581
                     /gene="raiA"
                     /locus_tag="PC466_001148"
     CDS             12018..12581
                     /gene="raiA"
                     /locus_tag="PC466_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HDF2768542.1"
                     /translation="MQIIVSGRQMKLTDGIKGYVDGKLSRLEKYLDPESEVKVTVSAK
                     KDRQKVEVTIIPINGQIIRAEDVEDDLYAAIDIVCDKLSRQVVKYKTKVKDKVQNNKS
                     IRFENLDFIDNSSEFDDYDYDDEEDENIVIERRKKFNVKPMSSEEAILQMELVGHNFY
                     MFRNQDNFEINIVYKRKAGGYGLIEQD"
     gene            12794..13030
                     /locus_tag="PC466_001149"
     CDS             12794..13030
                     /locus_tag="PC466_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YabP/YqfC family sporulation protein"
                     /protein_id="HDF2768543.1"
                     /translation="MLEISTDLQVNQPVITVTSNTFISIENYLSILEYEVDLIRIKTK
                     VKTIKISGDKLSLKYITDSEIGIKGIIYNVEYVD"
     gene            13043..14386
                     /gene="yqfD"
                     /locus_tag="PC466_001150"
     CDS             13043..14386
                     /gene="yqfD"
                     /locus_tag="PC466_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein YqfD"
                     /protein_id="HDF2768544.1"
                     /translation="MISFIRGYYVIVVEGVGLEQFLNHLIRNGISVYNVTRIKNTKME
                     FHIDRQDIKEFKNVYRGSKFDIKVKQKTGVPFIIKRVYKHKGMWICALVSLFLLMSTS
                     QFVTDVYIQSPEGIKKEALRNELYKVGVRPGVYKKSIDRKEVRDHMMSKFNDVAYLSI
                     NVKGTNIFVTVTKKAESLKSTDQSNYCNVIALKNGIIEKVIPRSGKSVIKSGDIVQKG
                     DVLLNGANTKSIPEVWASTFYESTKKASYVDTVNKKTGEKKNIYTLSFYDKEFTMRKN
                     IKYKDYVVENKEKKLSIGNYTFPIKIKTSTFYETKKVEVKRNKEELKKELSEKALKEL
                     EYIIPASARIIDVKHNFKVNKNMLEYLITVQTSENIAKIYPLSKSEAERFIKEESKPD
                     EGEEEVPSNPEKRPLNDIRNEFDEDNKDNKDQNNSDENNSNQNSNNSQNNNSNNN"
     gene            14325..15440
                     /locus_tag="PC466_001151"
     CDS             14325..15440
                     /locus_tag="PC466_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HDF2768545.1"
                     /translation="MKIIVIKIVIIVKIIIAITTNKIKLKILGGLIQLIIQKKFTIAD
                     GNFERELFGNFDENVKLIEKTLNIDVILREGNIILIGEEKNVDSALKLMNELHQTVSN
                     GKHLDKQSISYSLSLLLEGSEQKIKELEGTIVITQRGKAVQPKTLGQKEYIKLIENND
                     ITFGVGPAGTGKTYLAVAMAVKAFKRDEVSRIILTRPAVEAGESLGFLPGDLKDKVDP
                     YLRPLYDALFEMLGADKFNKYLERGTIEVAPLAFMRGRTLDNSFIILDEAQNTTSEQM
                     KMFLTRLGFGSKAVVTGDVTQTDLPQNKKSGLIQATEILKGVPGIGSIMLTDRDVVRH
                     ELVQRIIRAYEKHDKREEFKKEERKKVKMQEKTFKRK"
     gene            15497..15958
                     /gene="ybeY"
                     /locus_tag="PC466_001152"
     CDS             15497..15958
                     /gene="ybeY"
                     /locus_tag="PC466_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HDF2768546.1"
                     /translation="MDLILDDRQDKLEVSEELIEKIKDIIIECLDYEGYDDNYEVSLS
                     FVDNKEIHELNREYRGVDRVTDVLSFPLLSDDFEDVELEEESLGDIVVSLERALEQSI
                     EYNHSFEREVCFLICHSMFHLLGYDHDTDENTKEMREKEEHILNKLNITRE"
     gene            15964..16683
                     /locus_tag="PC466_001153"
     CDS             15964..16683
                     /locus_tag="PC466_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HDF2768547.1"
                     /translation="MKPEKTRQGIIKAFNAAIEGILYTFKFERNMKIHYLGSVAVLII
                     SLFFNFSKLEMIMLLMSICLVVVAEMFNTAIEKAVDLVTDEYHVLAKIAKDVAAGGVL
                     VAALNSVVVGYILFYDKLTDISGILIYKIRESELHITLICILLVLIAVVVVKALTSTG
                     TPLKGGMPSGHAALAFAIATAITLMTERVVASTLAYIMAVLVAQSRIEGKIHTFWETI
                     AGALLGVLIAILVFQLGMFYN"
     gene            16802..17203
                     /locus_tag="PC466_001154"
     CDS             16802..17203
                     /locus_tag="PC466_001154"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HDF2768548.1"
                     /translation="MDNIELLRLAEDARQHSYAPYSGFRVGAALLTKSGKVYTGCNIE
                     CASLGGTNCAERTAIFKAISEGDKDIYKIAIASDNSENNEQTYPCGICRQVIIEFGSD
                     IKIITGYTKGEVFEHSIKDLLPNYFSGNDLK"
     gene            17267..18160
                     /gene="era"
                     /locus_tag="PC466_001155"
     CDS             17267..18160
                     /gene="era"
                     /locus_tag="PC466_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HDF2768549.1"
                     /translation="MFKSGFVSIVGRPNVGKSTLMNNVVGEKIAIMSDKPQTTRNTIQ
                     AVYTDEEMQIVFLDTPGIHKPKNKLGEFMVKAATEAFKNVDLILFVVDDSKKIGPGDR
                     KIIEDLRSVKTPIILVVNKIDQLDQKDELFDIIKMYDREGIFKEIVPISALKGKNTDT
                     LIKVIQNYLEEGPKYFPDYMITDQPERVLIAELIREKVLHYLNDEIPHGVAVEIEKMK
                     ARNDKEIVDVSAVIYCERDSHKGIIIGKNGRKLKGIGKSARQDIELLLGSQINLQLWV
                     KVKENWRNLQNYINNFGYNDK"
     gene            18172..19551
                     /gene="mgtE"
                     /locus_tag="PC466_001156"
     CDS             18172..19551
                     /gene="mgtE"
                     /locus_tag="PC466_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HDF2768550.1"
                     /translation="MDRKLDASQDLLYEVKSLIDNNKVLELRELIEEYHIIDIFDIME
                     NLEEDMKIQLFEVLPLDMASSILEEGSVEFFISILSKLDVEHSKNILELMSLGDMADK
                     LSELEEEEREHIINLLNQENADYVKELLFYDEDSAGGTMTTGYISINKDMTALEAIDH
                     MREEAEEAETIYYIYVVDDEEKLVGVLSLRELIIARDANIVEDLMSENIISVYVDEDR
                     EEAVRLVSKYNLIAIPVVDRQEKLKGIITVDDIIDVMEEEATEDMYKFAGSSEHEREV
                     AEKENPTLREQIISALRGRLPWLIITLVGGLLASLILSNLDYIMNPVYAPLVFFIPVV
                     IGMGGNIGTQSSSVTVITLSNKDLNFSNVVREGIVGIITGLLCSIITGIVIYFVMRKL
                     DIVLIVSISLFINMVLGATIGAFMPVLLKKMDADPSTVSSPIISTALDITGIAVYFII
                     TTALLSKIV"
     gene            19624..19779
                     /locus_tag="PC466_001157"
     CDS             19624..19779
                     /locus_tag="PC466_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqzL family protein"
                     /protein_id="HDF2768551.1"
                     /translation="MNNISWEVFKKTGSIDAYLYFCDCKNIHEEIEEVREKKEDDDNP
                     EHPGDST"
     gene            19745..20518
                     /gene="recO"
                     /locus_tag="PC466_001158"
     CDS             19745..20518
                     /gene="recO"
                     /locus_tag="PC466_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HDF2768552.1"
                     /translation="MIILNTQGIVLKAIRYKESDIILTLFTRKLGKVSAIAKGAKKNK
                     SSLLSSSQLFSYSNFTLKKQGNMYKVTQSEIIKSFYNISYDIEAFSYATYITKLVENS
                     ILENQTNNRLFILLAQTLYLYTQDNTDNRFITAAFELKFLDYIGFKPIVNKCINCECK
                     ILQNSVFNIYEGGILCSKCSKLFDNNIKLDLTTISLMEYVLRNDILTCSKAKVSKYIT
                     HELENILDKYLKVYVDNINFKSLHVLQSVKNNKGVDNDE"
     gene            20511..21110
                     /locus_tag="PC466_001159"
     CDS             20511..21110
                     /locus_tag="PC466_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4342 domain-containing protein"
                     /protein_id="HDF2768553.1"
                     /translation="MSSNITIEMVDSVFERVPGATYAEAKEALVMCNGDVIEAVIYLE
                     NKKNTCNCKAKSAKETMEEVFGKDGENIKFQLKELLRKSSVVRIIVEKDGKTMMNIPL
                     TVGVVGLAFVPLATLVGLSAAVISKYRIKVQNEEDGEIVDLGELNEEKLHVLKNMITN
                     AAKDVKDVVVDKKEDDKDVTADLMKEESEKNKEDEDENK"
     gene            21270..22148
                     /gene="glyQ"
                     /locus_tag="PC466_001160"
     CDS             21270..22148
                     /gene="glyQ"
                     /locus_tag="PC466_001160"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HDF2768554.1"
                     /translation="MNFQEMILALQKYWSKQGCIMMQPYDIEKGAGTMNPNTFLRSLG
                     PEPWQVCYVEPSRRPADGRYGENPNRLYQHHQFQVILKPSPDNIQELYLESLKEIGID
                     PSEHDIRFVEDNWEAATVGAWGLGWEVWLDGMEITQFTYFQQVGNIECELETGEITYG
                     LERLAMYIQEVDSVYDLKWNDKITYGEVFNKAEYENSMYAFELCDADMLFNLFDIYEK
                     EALRLMENGLVIPSYDYVLKCSHAFNTLDARGAIGVSQRASFIGRVRNMAKTVAETFV
                     KQREEMGFPLLKDGDK"
     gene            22148..24214
                     /locus_tag="PC466_001161"
     CDS             22148..24214
                     /locus_tag="PC466_001161"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HDF2768555.1"
                     /translation="MKNYLLFEIGVEEMPSRFVGSTLEQLKNNLSKLFDENRIAFDKI
                     NAYGTPRRLTLVVEGLSDRQSDLEEEIKGPAKKIAVDAENNLTKPALGFIKSKGLSES
                     DIYFKQVGKEEYIFATIKQDGKETSEVLKDILPETIKSVVFPKAMRWGGKNLKFARPI
                     RWIVALLNDKVLEFDLEGIISSNVTKGHRFLGESTIEVDSIEDYFEKLEKNYIVLDQN
                     KRKEMIRKQCIEVANSLGGEVEFDEDLLEEVTYLVEYPTAFYGEFDVDYIKLPKEVVI
                     TPMKQHQRYFPVLKEGKLLPNFIAVRNGDSYRIDNVKAGNEKVLEARLADALFFYRED
                     TKRNLESYIEKLKTVVFQVKLGTIYDKTLRLEKLSADILDSLGLVDEKADTIRAAKLS
                     KADLVTGMVGEFDELQGFMGKEYAKVGGENDVVSEAIFEHYLPRFAGDILPKTNAGVA
                     LSIADKLDSIAGFFAIGIQPTGSQDPYALRRQALGILSILMDRKVAVDIKVLIEHALD
                     NYSELDFNKEEVVEQIMNFFNERVKNLFKDLGIRYDVVDAVLSSDINDVSDMHMRALE
                     LNNWLEKDELVEMLTAFNRVSTLAQKAESDKIDESLLKEDAEIRLYNEFKQVKVKVNE
                     LLKDKKYGIALDEFASLRPVVDNLFDTVMVMDNDEAIKNNRLALLKQVYDTMLEICDL
                     SKIVYK"
     gene            complement(24380..25927)
                     /locus_tag="PC466_001162"
     CDS             complement(24380..25927)
                     /locus_tag="PC466_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrite/sulfite reductase"
                     /protein_id="HDF2768556.1"
                     /translation="MDNFKKILLNELPNFKEYSSKFLNGEINKMQYKGFSGGYGVYAQ
                     RDKKSFMIRLRVSAGVLSQYQLNKIYEIAIKHNLDKIHLTTRQAIQLHDLSINSIVDI
                     MEEGIKNDIFTRGGGGNYPRNVGLSPLSGVDPSEVFDVTPYAVATDKYFIKNATTYHL
                     PRKLKVSYSNCYTDTAHCSIQDLGFVATLKNDEPYFRVFLGGGLGKQPKVALELDELI
                     KPKDALYCVEGMIKFFMDYGNYENKNRARVRYMVESLGEELFLEKFKEYYKLEKENGS
                     LELNIEEIDYSKPGVKIDIQDSRLIPQKQDGLYTVYIHPVGGILLTKDLSTLLKELDN
                     VENPMIRLGMTEGLYILNLNGNEAKRILEISKTISCNSQLEQSISCIGVPICQMGIQN
                     SQKMLHEIIDYFRLQNNEEILNKAPKLYISGCLNSCGVHQVGSIGLCGKKKNVDGIST
                     DAFELFVGGSFEIGKTRLGKSLGDFKASDIPEMLYKISDASSGNFYEWVNSNDNILNK
                     ITDKYKI"
     gene            26207..26974
                     /locus_tag="PC466_001163"
     CDS             26207..26974
                     /locus_tag="PC466_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HDF2768557.1"
                     /translation="MGEIINALDRALDIILLLYHEKREMGITEISKAMGVYKSTVHRT
                     LVTLENKGFVIQNAENGKYWLGINLYAIGMVVGEKMSLTEIVKPYTKKLNQEFNEVVN
                     VSILEERAQDSPRSIIIHKEYGSNQLLSVNPSVGSSSECYCSAVGKCLMAFNDSIDFE
                     KYRKTPIHKYTEHTIDNWDDMMLFLAKIKEQGYAIDDEELEHGLTCIGAPILDKNNKA
                     IAAISLSGPTIRMREGDFEYKIKRVIETAKSISELFR"
     gene            27257..27454
                     /locus_tag="PC466_001164"
     CDS             27257..27454
                     /locus_tag="PC466_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDF2768558.1"
                     /translation="MEKVKLSVERCKGCYLCIEACKKDAISLSDYTNKKGFVTIKVDE
                     EKCIQCGACYTMCPDLVFEIL"
     gene            27483..28559
                     /gene="vorB"
                     /locus_tag="PC466_001165"
     CDS             27483..28559
                     /gene="vorB"
                     /locus_tag="PC466_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate dehydrogenase subunit
                     VorB"
                     /protein_id="HDF2768559.1"
                     /translation="MQSLLIKGNEALAEGAIRGGCRFYAGYPITPQSEILEMMAWRQK
                     EVGGVFIQGESEIASVNMVMGASALGARAMTSSSGPGFSLKQEGIAYWVSAGLPAVVA
                     CVQRYGIGDGFIGAGQDNYWQAVKGGGNGDYHLIVLAPNSVQENMDMAYESFELAEKY
                     MHPVLILSDATIGQMVEPCIAPPMKEYDMDKAPWAAKGTPVGEKNKVITDITYFEDQD
                     TWQKGYIEKMRKVQEDEQRWEEIEIEDAEVVFVAYGISSRIAEGAVRDARAKGMKLGL
                     IRPKTLWPYPRKAFKKLSDSLKGLVTVEMNMMAQMKEDVIIACDNRFPVYSVATAQYM
                     AEVNQLIDFAQQIIDGKAKQEEVF"
     gene            28562..29281
                     /locus_tag="PC466_001166"
     CDS             28562..29281
                     /locus_tag="PC466_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate oxidoreductase"
                     /protein_id="HDF2768560.1"
                     /translation="MAKKAPAIMMCENMFCGGCGHSIVDRIIGEVLTEMDICQDTIIC
                     SDIGCNHMFQFSMNVDVVVPPHGKMGAAMAAMKRVRPDKYIFTIAGDGGAYAIGLGET
                     MSAATRNDNVIFLVMNNNMFAMTGGQMAPTTIEGQYTASTPAGRNYADHGSTFDVVKV
                     MGNLDIAYLARGTITNPKEINTTKRYIKKALEKQKEKKGFCLIEVLVPCPTNWGLKPV
                     DAMKRIENELVPKYPLGEFID"
     gene            29294..29833
                     /locus_tag="PC466_001167"
     CDS             29294..29833
                     /locus_tag="PC466_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase family
                     protein"
                     /protein_id="HDF2768561.1"
                     /translation="MLNEIICAGFGGQGVLTAGKIIMYVAYKAEKKITWFPSYGNEMR
                     GGSANCNVVVSDEKIANPCVKNPDILLGMNSVSVDKYESLMKKNGYMFVNESLVSKDR
                     KYREDINVIKVPVTEIAQNLGNEKAANICMLGAMVKSLDLFTKEEFESGMCEYFENQG
                     KGKFNSKNVEAFEAGYDYE"
     gene            29990..31048
                     /gene="buk"
                     /locus_tag="PC466_001168"
     CDS             29990..31048
                     /gene="buk"
                     /locus_tag="PC466_001168"
                     /EC_number="2.7.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="butyrate kinase"
                     /protein_id="HDF2768562.1"
                     /translation="MKVLVINPGGTSTKISVFQDENEILKKNITHTREDLKNFSKVFD
                     EYDYRKQLIVDILSSENHSINSFDAVVGRGGLMKAIKGGTYTVSEEMIEDMRNEINGE
                     HASNLGALLAKTIADEIGVQSFVVDPVSVDEFDDVSRITGISDIEKASWLHALNHKAV
                     SRKIAQKLGGKYEDYNFIVAHLGSGISIVAHKQGKMIDGSGGRSDGPFSPERSGGLLA
                     YPLIELCYSGKYTHDEMVAKVSSIGGMYDYLGTKDMIEIENRIKEGDEKAKLIMDAFI
                     YQVAKEISMYGASLSGNVDRVILTGGISHSEMVVKGVAEKVSYLAPIEIVPGEMEMEA
                     LALGALRVLNGEEIAKTY"
     gene            31066..31959
                     /locus_tag="PC466_001169"
     CDS             31066..31959
                     /locus_tag="PC466_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional enoyl-CoA hydratase/phosphate
                     acetyltransferase"
                     /protein_id="HDF2768563.1"
                     /translation="MLKDFNNLLEEAKKLEPVIVSVAVAEDKEVLKAVKSATDLNIIK
                     PILVGDKDKIESISREIGLKGHEIIGCQNPDESVKKAVEIVKNKEAKVLMKGLVNTSV
                     YMRAILNKETGLRTGRLLSLLAVYELPQYHKLLYCTDSGINVSPNLNQKKDIMTNALL
                     TMKSIGMENPKTAILTANEMVDPKIQSTVDANLLVEMEKSGEIPKCIVEGPIAFDVAF
                     DAHAAEHKGIKSNIAGDVDLLVFPNIEAGNILGKSWLRFNKAKWAGIVLGATNPIILG
                     SRSDTAEIKINSIALACLASQ"
     gene            31989..33197
                     /locus_tag="PC466_001170"
     CDS             31989..33197
                     /locus_tag="PC466_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HDF2768564.1"
                     /translation="MKYAKRMDMVKASAIRASQKKIAQKVASGGTVISFAAGLPDPNL
                     FPIEEISEITQKVLNERGKFALAYGPTKGEDELLDLLVKRMKEEENIDTKAENIIITT
                     GSQQGIALSAMILLEKGDIVVTENPSYLGAINAFRPYECDFLGVDTDDEGMVTDDLDK
                     LLSENSNIKVIYVIPTFQNPTGKTWSLQRRKDFMEVVNKYDVIVIEDNPYGEIRFTPE
                     PLPTLKSLDTKDKVLYLGSFSKVLCPGFRVAWMCGNVDIIDKAELLKQGIDLQSNQFS
                     QVQVIEFLKKYNLNEHIEKIRAEYKKRCLLMLDAMKKHFPEEAKYTEPDGGMFIWVEL
                     PESINVDDLLDKAIDAGVAYVSGESFFANNGPKNTMRLNYTTMSEEQIVKGVEILAEV
                     IKKELNYACE"
     gene            33221..34483
                     /locus_tag="PC466_001171"
     CDS             33221..34483
                     /locus_tag="PC466_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2768565.1"
                     /translation="MGEKENGIKFGKLMFQLVIIAISWELVYIIPFIQYTLYDPILKA
                     LECTNTQLGFLLTIYGLGNIFGAPIGGWLADRFDYRKIILGSVFLNGVVSFLFAFNMN
                     YPFAVATWVGCAITSLVMNYPSMVKILRVIGKDNQGKVYGFNEAMVGVSGVVMGAIFL
                     YIYTCFSTPVLGMRWVMISLGILSIVMCPVLWFVIKDVDIREDKEEEASEKMSAGDFM
                     TVLKSPNTWLVGISIFCVYSFTVTMSYFTPYITSVLGGSVALSGALAIIRQHGLKLFG
                     APFGGYCADKVKSPTKVLLPIYVFGIAVIILFLVLPASTPMTIFIALTFVVGILGYMG
                     KGIYYAVQDEVKVPVKYSATTIGIAAALGFSPDVFQFALIGHWIDTYGNKGYTYTFIF
                     QIAILIIGILSCLYILKVKKKRESKLEA"
     gene            35059..36522
                     /locus_tag="PC466_001172"
     CDS             35059..36522
                     /locus_tag="PC466_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine:cation symporter family protein"
                     /protein_id="HDF2768566.1"
                     /translation="MTDLVNTINGIVWSPVLVAMCLCIGLYFSMKLRFFQIKDVKEMF
                     TLLLEGDSSHVGISSFQGFATSMAGRIGTGNIAGVAVAIAMGGPGALVWMCIMATLGS
                     ATAFVESTLAQIYKDEHDGQYRGGPPYYFEKGLGWKKCSILFSVVAIISYTFFMPGTQ
                     SNTLYLAMNQAFGFSKMTIAVTSSIALGIIIFGGIKRIGLFAEKVVPIMGGAYLIMTL
                     VIIIANINLVPGAIMTMFKSAFGFGSVFGGMLGSAISWGVKRGIYSNEAGEGSGTYGA
                     AAAEVSHPAKQGLVQAFSVYVDTLLICMATGIMIIITGMYNVTDVYTTLPGVEPGPQY
                     VQSAINTLHPQLGDIFIAIVLLLFTFTTLLAFSYMMETNVSYLVTRIKAEKHEKHIIN
                     VCRFMLIICAAMCCFIEPLTSWALGDICIGVLTYINLVGIFTLKKPAIKAYYDYQRQK
                     KMGVKRSDRTFNPIELDIRNAEFWENRYLKEDKHELN"
     gene            36578..37714
                     /locus_tag="PC466_001173"
     CDS             36578..37714
                     /locus_tag="PC466_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HDF2768567.1"
                     /translation="MKERIIQVADSKKEKILGLCQSLYDEPEIALQEYKSAKKISEFL
                     REEGFDVEENLAGMATAFKATKKNGDGPKIAFIAEYDALPGNGHACGHHLIASMGVGA
                     GIALSSILDTYKGEVSIIGTPAEETGDGKPYLIEHGVFDGYDAAMMIHPNSKTCVTPE
                     IIAIGGLDFIFTGKASHAGAKPYNGINALDAVVLLYNNINALRQQLVDGTRIHGIILE
                     AGTAANVIPDMGKVRLEIRAKEQNYFDEVVEKVKNCARGAAIATGCELEFYHFEPTCQ
                     GLNENKVLVDIFTKIMEEFGIYEDEQVMLGSTDMGNLSQIMPCIHPLMKFSENGEELH
                     TKEFLEASINSYAKDRVIDGIKILALTGFNLFENPELLKKMKEE"
     gene            37950..39065
                     /locus_tag="PC466_001174"
     CDS             37950..39065
                     /locus_tag="PC466_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
                     /protein_id="HDF2768568.1"
                     /translation="METLEVRNIELSGTNYEIGYRLGELVANMPEIIEGQINKSNLVS
                     KKEEKEMIELFDKYCPGLNEELQGFADAIQVNCNQILYYTMTYLKPGCSQVALTPELT
                     ENGHVLFARNFDFSHNMEDFVLCKTKVNGKYAHIGTTVMQFGRGEGMNECGLGVSQSS
                     CGIPVGNSDGLRKPAIVGLQFWAVIRYLLENCKDVDEALEYLKDMPIAYNINLLLADK
                     SGNIALVETLDGKKEVNIINSLESKREYFLHSTNHTHIDKLHKLEPQSMKNSIHRYKL
                     IKEYINKAKKIGEKELMNLLSLKYPNGLSCNYYNDFFGTLKSIVMDLNIGKFNILWGG
                     LENKWESYYLKNDIKSITQRININIEKAPSDFFDFIE"
     gene            39217..40086
                     /locus_tag="PC466_001175"
     CDS             39217..40086
                     /locus_tag="PC466_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDF2768569.1"
                     /translation="MDYLKYFEKAVMYIENNLHENITVNDVAKETGYSYYHLTRLFKS
                     MFGESVGSYIKKRRLVSSTKELLYSDKKVIDIAIGSGFESSEAFSRAFKSIYKVSPIE
                     YRKNRIDVFVGKKKKLELDFMRHLVGNITIKPVIKEIEKIKVIGIKDKVILENNSLPD
                     LWEKFRKVHHIVPNTLPSKRVFGICEAISEIHLVSESMEFNEIIGLEVNSYDVIPNSF
                     VSKTIKEGKYAIFTHTGSLDNLDKTYEYIWGTWFLSSKEELDIRDDFEVYDERFLGPS
                     NVNSQIDIYIPIK"
     gene            40462..41007
                     /locus_tag="PC466_001176"
     CDS             40462..41007
                     /locus_tag="PC466_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HDF2768570.1"
                     /translation="MENVITGLSKGAEWFIGLFQKGGEQFIGLVSGTLPTLIVLMVAI
                     NSLIKIIGEERVNNWASKLGKNSFTRYILLPLVSVFFLGNPMCYTFGRFLKEEHKAGF
                     YDAAVSFVHPITGLFPHANAGELFVWLGISAGLTTLGKETTTLALWYFIVGLIVIFIR
                     GIVTEKMYAFLTRKNRATNKA"
     gene            41020..42033
                     /locus_tag="PC466_001177"
     CDS             41020..42033
                     /locus_tag="PC466_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HDF2768571.1"
                     /translation="MEENKILKIEKGTSGWGGPLYIKKEGNRNKILSMTAGGIHEVTL
                     KIKELLGCEIVDGFKTGVSDEEVAVVIIDCGGTARCGVYPKKKIPTINVNPVGKTGPL
                     AKFITEEYYVSDVNPNCISVVDGEDMPQKSQENKSENKSSIRKPDNYDEVKSKAQGEY
                     AKKNIILSIGQGAGQVVSKFYDAGRDTIQMVMNNVIPFMAFVSMLMGIILASGLGDWI
                     ARVISPLAGNIGGLLIISVICTLPFLSPILGPGAVIAQVVGTLVGTQIGLGAIPAYLA
                     LPALFAINGQAGCDFVPVGLSLGEAEPETVEYGVPALFYSRLITGPIAVIIAYGVAVF
                     ALR"
     gene            42255..44228
                     /locus_tag="PC466_001178"
     CDS             42255..44228
                     /locus_tag="PC466_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HDF2768572.1"
                     /translation="MSVTEKIPSIDRKIFKILIMCSKKEFVSINSIANELNVTTRSVR
                     TYIKQLNKDLGNDIAVIKYIKGQGYKLEIKDEQILNKIIDMNRKNVFSLNSKEDRVEF
                     ILNYLIELDGFITLDSLADEMCVGRTTLVNDFQYVEKVLASYNLNLIKKQNTGMKLNG
                     NELDIRLFILNQLYKNSRKDFSNSKYFKGIKKEEIINLEEKLLTLFKENNFYVTDEML
                     REVINYIVVLVYRVKEEKKVKDYDVKFDLLKSYDEYFIAREIKHIISGMFECTLNDEE
                     IIYLTIPLVSGNAPASECALNSSRISKNIDELMENIFNQIYVDMGIFINEDELRVGLG
                     YHLSFTLNRLLFNIKLKNVLLEEIKQNYILPFKLAQIAGKVIEKKYNLEVSEDEIGYI
                     AIHFSGYLERNSSRFYSIKKIAIICSTGLGTAKLLKIRVEKLIGNNPKIDTLSSFNLR
                     NINLDEYDIVFTTIDLDTSNINTIVLKINTIFDENKLREQLKTVLCLREGNIDTTNST
                     NLLINNLLDEDKFMILNEKTILASLEKMMDHLMDLGCIDDKFRKNIVNREEKSPTVFD
                     KGLLFPHSVNEKSDKFLMAVGILEEPIEYANRSIKIILMTMFPCENKIDSDLLVKIYE
                     EVLKIGQDVKLTNKISKCRTFLEFKKVLLKNLI"
     gene            44297..44656
                     /locus_tag="PC466_001179"
     CDS             44297..44656
                     /locus_tag="PC466_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768573.1"
                     /translation="MKLLVILFVAYILNTIFIMKQNKLYFKTLNRAKKKGDIVSTGKK
                     KSYFSKGSIAIISSDSDGFIKFGEILKGRTVMAKFKEIEEIEGLDIYSAEQKFKDEES
                     IVQAIKFIKEKINVSFN"
     gene            44691..45047
                     /locus_tag="PC466_001180"
     CDS             44691..45047
                     /locus_tag="PC466_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HDF2768574.1"
                     /translation="MKYEVKISGIGSLVKELMDESNCLIIYDETINDDDLKDISVIHS
                     IATLKSDVEIGDTLTIGNRDYCIVSVGDIAQKTLREIGHCTIKFDGKCEVNLPGEIHV
                     EIGNPDITIGDLITIS"
     gene            45084..46376
                     /locus_tag="PC466_001181"
     CDS             45084..46376
                     /locus_tag="PC466_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HDF2768575.1"
                     /translation="MLDLNRKLAKLEEEGKKIKVALIGAGHMGNGMVSQMANMKGIEA
                     SIVVDINLELAHKAFTDAGIDEEIIDNVTNEKDAEIKLQEGKVLTCNDFLVACKTKSI
                     DVVIDATGGIAIGAEIALNSILNKKHIVMLNAETDCVVGPILKKLADDAGVIFTGSAG
                     DEPGAVMELFDFADAMGFEVRVIGKGKNNKLDLDCNPDTVREEAERKGASPHMIASFK
                     EGTKTMVEMALMCNATGFVPDVRGGHGIEATVNEVPKKYALKSEGGVLDNYGVVDFVN
                     GIAPGVFVVVAHKLKAVNDELKYLSMGDGPNYILYRPYHLCSLETPLSAAMAVLDHKA
                     TIVPKAGLVAEVMTIAKKDLKKGEFMDGYGAYTCYGTIEKYDVAKAMNAVPIGLISKK
                     TKVVKDIKKGEVITYDMVEIEKDTTLYHLRQLQEKIFG"
     gene            46812..47450
                     /locus_tag="PC466_001182"
     CDS             46812..47450
                     /locus_tag="PC466_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2768576.1"
                     /translation="MIIIQLNERQLKIIDIVKENEPITSESIASSLNVTRATLRSDLA
                     ILTMTGILDARPKVGYFYSGVSEINLIGKSVKEKTVEDIMSMPVLAKKDESIYDVIVT
                     MFLSDVGSIVIIDENEELCGVVSRKDLLKATIGGSDINKMPIGMIMTRTPNVVTLTKG
                     ASVLLASRKIIEHEVDSIPIVEYKGEDKNHMRVVGRISKTNITKLFLEIVDN"
     gene            47457..48299
                     /locus_tag="PC466_001183"
     CDS             47457..48299
                     /locus_tag="PC466_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase/pyrophosphorylase"
                     /protein_id="HDF2768577.1"
                     /translation="MLVKNLIIYAVSDSVGETAQQVAKACMSQFYVNETYEIKRFPYM
                     INKGVLLETLENAKAENALIVYTLVDEELCSIVERYCEREGLSCIDLMTDILREISKR
                     TGRKPKREAGIIRKLDESYFKRVEAIEFAVKYDDGKDPRGVLQADIILVGISRTSKTP
                     LSMYLANKNIKVANVPLVPEIPIPKEVFEIDTKKIIGLTNSPEKLNEIRTQRLKALGL
                     SSKANYANLERILQELDYSEEIMKRIGCPVINVSNKAIEETAGIILDIMKENGLKIYK
                     EIEI"
     gene            48360..50987
                     /locus_tag="PC466_001184"
     CDS             48360..50987
                     /locus_tag="PC466_001184"
                     /EC_number="2.7.9.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate, phosphate dikinase"
                     /protein_id="HDF2768578.1"
                     /translation="METKYVYSFGEGSKDMKSLLGGKGANLAEMTKIGLPVPPGFTIT
                     TEACNDYYVNNESIRAEIIKEIEEHLATLEKDLNKTLGCNKNPLLVSVRSGAVFSMPG
                     MMDTILNLGLNDNSVVGLAEATQNERFAYDSYRRFIQMFSDVAMEVPKYKFENVLDRV
                     KEAKGYTVDTELTTDDLKEIVKEFKAIYKKEIKNDFPQDPKEQLMLAIEAVFRSWNNP
                     RAIVYRKLNDIAHNLGTAVNIQSMVFGNMGETSGTGVAFTRNPATGENKLFGEFLMNA
                     QGEDVVAGIRTPQNISTLADVMPAVFDEFVKITHILEGHYKDMQDIEFTIENERLYIL
                     QTRNGKRTAAAAINVAVDLVEAGIIDEKEAIMRIEPNQLDQLLHPKFEDKALKEAKVI
                     AKGLPASPGAASGKVYFNADDVVKANEKGEKVVLVRLETSPEDIEGMVKAEGILTARG
                     GMTSHAAVVARGMGKCCVAGCGEIKVDEFNKEIRALDDVVIKEGEYISIDGSTGNVYL
                     GDVKKTEVSLTGNFEKLMNWVDKHKCMMVRTNADNPRDARAAIEFGAEGIGLCRTEHM
                     FFDEARLPAVREMILSNTVEQREKALEKILPMQREDFVELFKVMDGKPVNIRLLDPPL
                     HEFLPHDDETIEELSKSMGIKVSDIKKRIVDLDEFNPMLGHRGCRLAITYPEICVMQS
                     KAIIQGAIEAIKAGVKVSPEIMVPLVGEVNELKIIRKMIVETVDAIIKEEGIEVPYTV
                     GTMIEIPRACLTADEIAQEADFFSFGTNDLTQMAFGYSRDDAGKFLGQYVDEEILEKD
                     PFQVLDQNGVGKLVKMGAKLGREVKPELKLGICGEHGGEPSSVEFCYSVGLNYVSCSP
                     FRVPIARLAAAQASIKNPR"
     gene            51201..51446
                     /locus_tag="PC466_001185"
     CDS             51201..51446
                     /locus_tag="PC466_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HDF2768579.1"
                     /translation="MTKCPKCGKEVSSRPGSICPRCGFKVADESLKIRCPEPSCRALV
                     SRKLDYCPKCGCKLRGYNISEFVNMVRCKIDETFDKK"
     gene            51658..>51771
                     /locus_tag="PC466_001186"
     CDS             51658..>51771
                     /locus_tag="PC466_001186"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDF2768580.1"
                     /translation="MSKKHKKYSKELKLKAVNLYIKEGYSSYKIAEMLNIRS"
BASE COUNT        20710 a         5305 c         9680 g        16076 t
ORIGIN      
        1 aataatgaat tatactagaa agtaggaggt gaaaatatga gcagaatttc aatttttatg
       61 gagtcatgta atggcaaatt tccaaatgaa aattcaatgt tgtcagtttc ctttataaaa
      121 aatattttaa atgcagaaaa caaagatttt gctaaaaata tatttaacta tggggaagaa
      181 agaaaaaaca ataagcaaat aaaggatata aatacagcca tctacatacc aaatcttata
      241 agaagcaaaa atgagttgct tgttgatgga gatataatat tcaatataag tttttataat
      301 tattctatgt tcagtaaatt atacaatgga attttaaaag taaaggagct agaatataaa
      361 ggttatagat ttaaaataaa aaatataaaa atacataaag aacacgagat aaaagaaaat
      421 ggtgttatat ttaaaactat gtctcctata atagtaaaga ataaagaagg taaatattta
      481 gatgtagaag attcaaatta tatagaatgt ttaaactata tagctaatct aactctggag
      541 agtataagag gtagtgggct tagaaagcca ttggaattta tacctcttaa cttcaaaaaa
      601 agagtgttaa aagaaaagat tcgtggattt aaagtgagag aatattacta tataaatgct
      661 tatgcaggaa catttttttt aaaaggaaat atggaagatt taaatgcact gtataaaatg
      721 ggaattggat atagaaggac ggaaaatgca ggaatggttg atatattaaa gtagcgaggt
      781 gagagaaata aaagctaaat tttatagatc aggtgatatt gtaagagata ttggcattgt
      841 ttacttttat gaattactaa tggatttaaa aaacgaacta gaaaaaaatg attataagct
      901 aaaatttact tgtgagttaa atagaaatta tttatcttta gaatctgcag aatatataga
      961 ccctaagtat atatctgatt atatattaga aaatcaactt tttaaggtat ttaaaaatgg
     1021 gaaaaaggaa accttagaaa aaatatttag taatatagat aatttaacgt atgtaaattt
     1081 tattgaagaa ttagataaat cttctgcaac tgagaaacaa aaggaaggga ttaaaaaaga
     1141 ttttaaaaac agaagatttc catatgttag aaatagtggt aagtatggat taaacacgag
     1201 tttagaaaat atggaaacaa atgtaaaaag aatagtagat actgtaatta aatcaaatat
     1261 agagatagat gaaatagata aacttgattt gacacaatat gaagaaaaag atagtgtatg
     1321 taatgtttgt aatataaata aaacaacaaa actagatatt gatttaagag agcgaaagga
     1381 ctctaagtat aactttttat ttagaggtgc agaaaaatca ggctttaaaa gaagtggaca
     1441 agttgaaagt aatatttgtt ttgagtgtga atttttcaac ttaatgtgtc ttttatatat
     1501 aaatttaaaa agaccaatgg tttttgcata tacgaatgat ttaagggaat tagcattttt
     1561 aaatcataag ataatgctta aaagaaagat gtattcagat aaatcatttt ataaaaaact
     1621 tttgcatgaa aaaataagtt cgattagact atataggttt gatattgata cgaataaagg
     1681 tataattcta aagtttgact ctattataga gtataaagaa ttattaaaaa aaattgaact
     1741 tatagatatt atagataatt ataatttttc aagagagcca gggaatacta gaaatttggg
     1801 taaaaaaatg attgataatg ggaatttatc aaatttaaaa gaattattac ttgataatat
     1861 aagtgtttta aggcaactaa ctggaacttc tcgagaaatg gattttgtat ctagctcata
     1921 taatatcggt ttatatataa aattgtgttg gattgtagat ggaggggagg agtataaaat
     1981 gaaaaactat atggaaagta atttaatata ttcaagagta ggtaaagact tatttaataa
     2041 aatgacagat gaatccagaa gaaaaaattt ttctatgaaa gtgattcaac tacttaagtc
     2101 taatgataga actcagctat ttcaaactat aatgcatgtg ttagtttcta atggaatctt
     2161 aataggagaa gggtttgtag aaggtctaat gcagagttct gaattagaat taaatacgaa
     2221 tgtaggtcta tttattcaag aaatcatgaa ataaaaaagg gggaaaattt aaaatgaatg
     2281 aaaaaagagt aaaaggagta acattaacta tactgacaga aagcccagtt ccactttcat
     2341 atgaccaagg gtatggaaat tatacaccaa taaaaaaaga acaatataga gaaaaaatac
     2401 atgcaaaaac tagtatagcc acaataacat atgatttaag aagaatgctc caccaagaat
     2461 atggttggaa tttaagtaat attatttttg ggaaaaaagg aaatatatat ccatctatta
     2521 agcaaaatgt aggatgtgta gatgaaaatg gattagagac tgatgtattt ggttatttga
     2581 taccacttaa agataaaggt tctataagta aggcttctcc gcttagaata atacctttta
     2641 ggtcattaaa ttcatataga ggttcaacac agttgataac aaatagaggt tttttaagta
     2701 gcgaatttgg tagaaaatat tatgatgaga aggaagaaaa tgaagtactt agagatgaaa
     2761 actttccaac atcacaagca ttagcaatag aagagacttt atcagattac tacgtttata
     2821 caataacatt ggagcttgat agaataggag tagtagaagt agaagatgga aagttgcttt
     2881 taccagaaga aagaaaattt atgagtaagg agttaagaga aaaagcagta aaagatatat
     2941 tagatgcaat tactgtgttt acaagaaaca taaaacattc atcagtactg ttaaaaccac
     3001 ttgcagtaat gggtggagct tttgataaag ttgtaccgtt tttttgggat gatgtagatt
     3061 ataatgctga tagtggtgag ataaatttag agggagtcat agaaactata gaaagttata
     3121 gccttaaaga aagtaacaca atacttgcta tcaatgacaa attaaaaatt tctaataaaa
     3181 aggaattaaa taagtttaat ttaagtaaat accctgtaaa agagattaaa aatctagcag
     3241 atagattgga aattggagaa gataatatgt ggtatttaaa agagtaggag gttttttgaa
     3301 ttatgaaagt attacaatgt aaacttaagc aaccaactgc tcactataga gacccaaaag
     3361 tatttcaaaa tgaatatata agtactttaa atttaccatc taagaccaca ataatgggaa
     3421 tgataacgta tttatgtgat agaagattaa actctgatat agatatagga ataattggaa
     3481 cacatcatca tagagaacta gaattttcaa gaggagagaa cattgatttt tggaatgaat
     3541 atacaaatat gagaaaaggc aaagataaag aaaagttttt gcttcaagga aactactatg
     3601 attactataa agaacataaa gctcaaaata gcatattaaa ctatgaagtt cttaaagaag
     3661 tagaactgac tatatttatt tcttgcaagg atgatgaaga acttgaattt attaaaaaaa
     3721 agcttgaaag tccatgtaaa tatgcaaatt taggaagaaa agaagatttt gtaataccaa
     3781 gtgaaaaagg gtgttttgtg aaagaagttg agttaaaaga ggttatgcct atgaatactc
     3841 gtgatgctat aaaagaaaat ataaaattaa agaatacata tgtaagagtt gacttaagag
     3901 ataaagagaa tgtcgagact ataataaatc aaggtgtatt gattgcatta ccttataaat
     3961 ataaagattt agaagcaaat agagatgata gagtttatga gttttgccat tatatatatg
     4021 ttgataatga tggtatatat cctaaaaata ttaaggtaaa tgtatgtaat gtatgtattg
     4081 atacaaaaga agtttttaca tggctttaaa ttattttgaa agataggtgt ttatcatgaa
     4141 aaatatcatg caaaaagaaa tattagctaa gtcatataat ttaagaacta atcaacaaga
     4201 acaaacatta gttgaacata ttaaggattt atttgaagta ttagaatcta tattagaact
     4261 aaatctatat tcagataaag atgtagagat actaaaaata tgttgtgctt tgcacgattt
     4321 aggaaaaatt aattcaatta tgcaacaaaa aatggagatt aataataaaa tatcgtatag
     4381 ttgctcagaa gaagagagga aaaagttaga gtctgacaaa aaatctttaa aaaagatagc
     4441 aagacacaat atattttctg gagcattttt aaaagatata ttagaaaaaa tgaacttgtt
     4501 agaagaagat aagttatata tatataaaag tataatgtta catcatggaa actatgaaga
     4561 ttatatgagg ttaagtacta gtaaagttca agaagaaatt tatgattata ttgaaaaagg
     4621 cattttagaa aaagaagagt ttaatctgaa agatatagaa agttatataa atgacatttt
     4681 aaatgtagat tttaaatttg gtgaagatgt attggattat gattacatag ataaattaag
     4741 tgaaagtatg tttatagaca gtgattataa caatggtcaa atagatgatt cagttttaaa
     4801 ttatagaaag tttaagtata ttttatataa agggatgctg aacttaatag accatagtgc
     4861 atcaagtaga cagaaaggta taaaatttta taacgatttt actgatgaag aaattgatga
     4921 tatgatttta aatgagatat ataagagtca gggtaattta gaaaaaaata atatagagtt
     4981 caatactata caaaaaaggt tgagagaact ttctggaaga aatgttctga ctgttgcatt
     5041 tacaggttca ggaaaaacag ctgcagatta tagaaagact tttaaaagaa aattcttttt
     5101 agtgccaaat aaaatatcag cagaaagttt ttatagaaaa aatatttttc aaaataaaaa
     5161 tgatttagat acaagaagta gtaatgatta cattggatta cttcatggag atataaactt
     5221 atattcagag aatgaagata atggagaaca tgattttgta ttgacattaa gggatataga
     5281 tttgagtata aatttttgta aaccttgtgt aattgcaaca gttgaccagt tattacttag
     5341 tatgtttaaa tttccgggat atgaaaaaat attcgcagcc gtaaaaaatg catctataac
     5401 tgttgatgaa gtacatttat tggaaccaaa gatgtttttg attttgatat attttatgca
     5461 gtttgcatgc aagtacttag atgttgattt tcacttaatg acagctacac ttccaaaatc
     5521 atataaagag caaatgataa acaagggaat tatttttcaa gaagaaagta atgaaaatgt
     5581 tactgataaa ggagaaatag tttttattga gagcaacaag gaagaagaaa tttgtgaagg
     5641 taaagatgta aaggtttctt ttataaagga aaaagaaatc aagtcaatag ttgaaggtgc
     5701 tttagaaaat aaacaaaaaa ttcttataat aaagaatact attgattcag tcaatagaac
     5761 atatgagttt ttaaaagaaa atttatctga taagtatggt ggtgtagata tagatgtttt
     5821 acatagtaga tttaagttca aagataaaaa agagaaatat agtaaaatat taaatggaga
     5881 gggtgatatt tggatatcaa ctcaatcagt agaaatatcc ttggatttgg atttcaatat
     5941 aataataagt gatttagcaa ctatggatag cttaatacaa agaatgggta gatgcaatag
     6001 aaataataaa tatgaatatg gaaactttta tattctacct agtgaagata aaatttatga
     6061 taacaaactt aagaacacaa ctaaaaacat cttaaaggac atattaaaaa ctaactctat
     6121 ttttacaatg gggattagaa aaactatttt ggatgattac tatgataata gtgtagttaa
     6181 aaactatttt gaagagaatt ttataagttg tgataaagaa attaagaata tttatggtat
     6241 aaataaagaa atttttgatg gattggattt aatttttaat tttgaacctt acaaaaatat
     6301 tgttgatagt aagaaggaag cagctaaaat ttttagagat gttgatgtta gttacaaaat
     6361 tattctggaa gaagattttt ataaggaaga tagggagtta caacaagatt cgattcaagt
     6421 atcagggttt atatttaata gattatatta ttatggatta ataagcaaag tagaaggata
     6481 catggtacta aaatctagta gtaagtttga gtataatagt actgtaggct taattttgaa
     6541 gtgagcatat gtttaaatat aatatacctt tagacattga aaatacaaaa agtactactg
     6601 taagcccact gtaaaaacta ttttttaaaa ggaaaaataa gttgtgagat agagtgtcta
     6661 caagtgtata tagataataa atttgaggtt taagattaac taagtgggtt tcaggtacat
     6721 cgcgaaaata attataagtt ggagattttg tatgtttaag attaactaag tggatttcaa
     6781 atattgatat agtagatata atagaagttt tattattagg tttaaaatta actaatcgga
     6841 tttttaaata ttctgactat tatataagga tattattagc ttgaatttaa aaccaataat
     6901 ataaaacaac aaaatattat atttatgata taataaaagt tatggaaaaa caggaatatt
     6961 actatagaga agagaggtaa acttatgaat aattggatag aagtaactat aaaaacaaca
     7021 acagaagcag ttgaacctat aacgaatata ctatatgaac aaggagctgg aggagctgta
     7081 atagaagacc caaaagactt tttattccaa aagaaaaatg aactagactg ggattatgtt
     7141 gaagaagaag tatttaaaaa gaatgaagaa gatgatgttc ttataaaaac ttatgtttct
     7201 gaagaaaaaa atgtgatgga atttgtcgaa ataataaagc aaaaagtttt aggattaaaa
     7261 gattttggta tagatatagg tgaaggaagt gtatcattgg accaagtaaa tgaagctgat
     7321 tgggcaaatg catggaaagc atactacaaa ccaacaaaag taggacaaag ggtagtagta
     7381 aagcctacat gggaagatta tgctatgcaa gatggggatt taatcataga gcttgaccct
     7441 ggaatggcat ttggtacagg gacacatgaa actactagta tgtgcattag agaattagaa
     7501 aagtatgtga ataaagattc taaagtattt gatattggat gtggtagtgg aatccttgca
     7561 atagcagcag ctaaattagg agcaaaagaa gttgtagctg tagatttaga tgaagtggct
     7621 gtaaaagttg caaaagaaaa tgttcttgaa aataaagttg aaaaaagtgt atctgtaatg
     7681 catggtaatt taactgatgt aataaaagat aaagcggatg taatagttgc aaatataata
     7741 gctgatataa taaagatact tgcaaaagat gttcaaaact ttatgaaaga agatgctata
     7801 tttatatctt caggtataat tttggataaa gtagaagaag ttaaagaaag cttaattgaa
     7861 aatggatttg aaatagttga agttcaaaaa ttaggtgaat ggtcagcaat agtttctaag
     7921 cttaaaaaat aagggatatg gtgacgtata atggatagat tttttgttga aaaaaataat
     7981 ataaatctac aagataaaac ttgcactata gaaggtgaag atgtaaaaca tatttcaaaa
     8041 gttttaagat gcaaactagg tgagaaactt gaaatatgtg acaagaataa taatgagtat
     8101 atttgtgaga taatgaatat agataagagt atagttaatt tagagatttt agaaaaagtt
     8161 gatataaata gagaatcaga acttaaagta aggttatacc agggacttcc aaaagctcca
     8221 aaaatggaaa tgatacttca aaaattaact gaagtgggtg tagaagaaat aatattagtt
     8281 caaactaaga gaagtgttgt taaagttgat gacaaaaaag aagataaaaa atttgaacgt
     8341 tgggaaagaa taatttatga agcagcaaag caaagcaaaa gaggtaagat accaaaatta
     8401 agaggtgttt taagttttaa agaagcttta gaagatatga aaaaaaataa tgtaaatatt
     8461 tgcccttatg aaaatgaaag aacagtttca ataaaacatg cactaaaaaa atgtgattct
     8521 aatatagata gtgttggaat ttttataggt ccagaaggtg gattttctga agaagaaata
     8581 gagcaaatac aaaaaaataa ttgtaatgtt gtatcattgg ggcctagaat attaagaact
     8641 gagacagctt ctgttgtagc atcaacaata gctttgtatg aactaagtga tttaggagga
     8701 gaaaaataaa ttgaaaaaag tagcttttta tacacttggg tgtaaagtta atcaatatga
     8761 aacagaagct atgctagaac tatttgagaa agatggttat gaacaagtca atagtgaaga
     8821 gtatgctgat gtttatgtta taaatacatg tacagttact catatgagtg atagaaaatc
     8881 tcgtcaatat ataagacgag ttaaaaagaa gaatccagat gcaataatag ccgttgtagg
     8941 atgttattct caggtatctc cagaagaaat tttggatata gaagaagtaa atttagtcat
     9001 gggtacaaat gatagaagaa agattgttga agaaattaaa aagataaatt caagtaagaa
     9061 agttagtaca gttgatgaca taatgaaagt taaagctttt gaagaaatag aaatcagcca
     9121 aactaatgga aagactagag catttatgaa aatacaagat ggatgtgaca gattttgtac
     9181 ttattgtatc attccttatg cccgaggacg cgttagaagt agagatattg atagtatagt
     9241 cgatgaagtg aaaaaattgg ctaataatgg ctataaagag gttgtattaa caggaataca
     9301 tgttgcctct tatggaaaag atttaaagga tagggatatt aaacttcttg atgtaataaa
     9361 acaaataaac cagatagaaa aaatagaaag aattaggctt agttctgttg aaccaatttt
     9421 atttacagat gaatttgtaa atgaagtttt aaagatggat aaagtttgtc ctcattacca
     9481 tttatcactt caaagtggat gtgatgaaac tctaaaaaga atgaatagac gatacacaac
     9541 tttagagtac aaaactattg tagatagatt gagaagtaaa atgccagatg tggcaataac
     9601 tacagatgta atagtaggtt ttcctggaga gacaaatgaa gagtttaaaa aaacgtacga
     9661 gtttttaaaa gaaatagagc tttcacaaat gcatattttt aaatattcac caagaaaagg
     9721 aactccagct gcaactatgg aaaatcaagt tgaccctcaa atgaaacact ttagaagtga
     9781 acaactttta aatttaagta aagtaaattt taataaattt gcaactaaat ttatcggccg
     9841 tgagctggat gttttgtttg aacaaaatat agaaggcaat aaatatgagg gattaacttc
     9901 aaattatata agagttgttg ttgaaagtga caaaaatata caaggtcaga tattaaaagt
     9961 gaaaataaat gatgtaaaag atgaatatgt agaaggaatt ttgctataac atgtagaaat
    10021 tataatattt ataagatagg aggtggaaag aatggattgt attttttgta aaatagcgaa
    10081 cggagaaata ccttcaacta aagtttatga agatgataga gtcttagctt ttaatgactt
    10141 gaacccagtt gctccatatc atatattagt tgtacctaaa aaacattatg atagtttaat
    10201 tgatattcct gataaagaga tggacattgt gtcacatatt catgttgtta ttaataaaat
    10261 agctaaagag aaaggttttg accaaactgg attcagagtc ataaataatt gtggaagtga
    10321 tggagggcaa gaagttaaac atttgcacta tcatatttta gctggtaaaa agcttcctaa
    10381 ttacgaagcg ggacaaaact aaactaaatt attgaaaaat tgagttcctt cttgataaaa
    10441 atacttgata aaagtaaaaa tttagtttat aataaacaaa gtgttaggtt gtaatgcata
    10501 ttatgcaaaa agaacatagt tacagtccca gcataattgc gctattggag ggagggaaaa
    10561 agaaatgtca gaagtaagag ttagagagaa tgaaacatta gacagcgctt taagaagatt
    10621 caagcgtcaa tgtgcaatgt ctggcatcat gtcagaagtg agaaaaagag agcactatga
    10681 taagccaagc gttaagcgta agaaaaaagc tgaagcagca agaagaaaaa acgctaagaa
    10741 atagtagtaa ataagaataa agaggtgaag gggatgtccc ttaagcaaaa gttacaagag
    10801 gatttgaaat cttcgatgaa aaacaaagat acagtgagaa aatctgtagt aactttaata
    10861 agagcttcta taaagcagta tgaggttgat aatagggtcg agcttgatga agatggaatt
    10921 atcgatgtaa tagcaaaaca attgaagcaa cgtagagatg cattagttga atttgaaaaa
    10981 gctggaagag aagacttaat aaaagaaaca gaaggtgaaa ttgaagtttt aaaagagtac
    11041 ctacctcaac aattaagcga agaagagtta gaagaaattg taaaatctac tatatccgaa
    11101 gtaggggcaa cttctatgaa ggatatggga aaaataatgt cagttatcca accaaaagtt
    11161 aaaggaagag ctgacggaaa acttataaat aagttggtaa aacaaaactt acaatagatt
    11221 gatatagcct agagagaaat ctctaggctt tttatagttt ttgggaataa cgagtcatat
    11281 ttgagcatat ctataatcaa agaaaatttt gaaagaaggg gaaaaatttg attatatcag
    11341 taaaagagat taggaatttt ttgataaaca tatttatacc actaataata ggttacttaa
    11401 gtagcatctt aacaatgatt atcagtggaa cagatatttc aacctattat ttacaactca
    11461 caaagccaag ctttgcacca ccagctttta tctttcctat agtttggact atattgtaca
    11521 tattgatggg tatatcttca tacctaatat taagaaaggg ttacaactta cctaaggtaa
    11581 gagatgcaat tttttattat ggattacaac ttgtattaaa ctttatttgg agtatactat
    11641 tttttggatt tggacttaga tttacagctt tgatagatat aataataatg attttggttt
    11701 ctataataat gatttcgaag ttttctaaaa tagataagag atctggatac ataaatttga
    11761 tttatttaat gtggcttgtt tatgcaggat ttttgaacta ttttatatgg tttattaata
    11821 aatagaatgt aaagattttg taaattaccc tgtactttta ataatatcat aacaaacgaa
    11881 aaataaatag actattaaaa ataatcattt tcatatacaa taatattaat ttaaatacaa
    11941 taaatttata aaaattgtat ttaaagatta acatattaaa gtattagaat tggaaaggct
    12001 tgaagggaga ggtttttatg caaataatag tatctgggag acaaatgaaa ttaactgacg
    12061 gaataaaagg atacgtagat ggaaaattaa gtaggttaga aaaatacctt gatcctgaat
    12121 cagaagtgaa agtaacagta agtgcgaaaa aggatagaca aaaagtggag gttacaataa
    12181 ttcctattaa cggtcaaata ataagagcag aagatgtaga agatgactta tatgcagcaa
    12241 ttgatattgt ttgtgacaaa ttaagtagac aagttgtcaa atataaaact aaagttaaag
    12301 acaaagttca aaataataag agcataagat ttgaaaatct tgactttata gataatagca
    12361 gtgaatttga tgattatgat tatgatgatg aagaagatga aaatatagta atagaaagaa
    12421 gaaagaaatt taatgtaaaa cctatgagtt ctgaggaggc gatacttcaa atggaactag
    12481 taggacacaa tttctatatg tttagaaacc aagataattt tgaaataaac atagtgtata
    12541 agcgtaaagc tggtggatat ggtttaatag aacaagatta ataaaaattg tatacgttta
    12601 gattttatat aagaaaaaat aaaaaggtaa tcatgttgat tttttatcaa tatgattacc
    12661 tttttattgt ttaaataata tattagatat taggtattta ttatataaaa attttaaaac
    12721 taatctgtta caacatcaat aaagtgcata aatacctatt tcaagcataa aattaattaa
    12781 gggggtaatg cttatgttag aaatatccac tgatttacaa gtaaatcaac cagttattac
    12841 tgttacaagt aatacgttta ttagtataga aaattatcta tcaatattag aatatgaagt
    12901 tgatttaata agaataaaga ctaaagttaa aacaattaaa atatctgggg ataaactttc
    12961 acttaagtat attactgata gtgagatagg tataaaaggg attatctaca atgttgagta
    13021 tgttgattag gaggagatac acttgataag ttttataagg ggatactatg ttatagttgt
    13081 ggaaggagta ggactcgaac aatttttaaa tcatcttata agaaatggga taagtgttta
    13141 caatgtaact agaataaaaa atactaaaat ggagtttcat atagatagac aagatataaa
    13201 agaatttaag aatgtttata gaggaagtaa gtttgatata aaggtaaagc aaaaaactgg
    13261 ggtccctttt attatcaaaa gagtttataa gcacaaaggt atgtggattt gtgctcttgt
    13321 ttctttattt ttattgatgt ctacatcgca gtttgtgaca gatgtatata tacaatctcc
    13381 tgaaggtata aaaaaagaag ctcttagaaa tgagctttat aaggttggag taagaccagg
    13441 agtctataag aagagtattg atagaaaaga agttagagac catatgatgt caaaatttaa
    13501 tgatgtggca tatttatcta tcaatgtaaa aggaacaaat atatttgtta ctgttacaaa
    13561 aaaggcagaa tccctaaaat ctacagacca atcaaattat tgtaatgtaa ttgctttaaa
    13621 aaatggtata atagaaaagg taatccctag aagtggtaaa tcagttatta aatctggaga
    13681 catagtccaa aagggagatg tcttattaaa tggagctaat accaagtcaa taccagaagt
    13741 atgggcaagt actttttatg agtccacaaa aaaggcaagt tatgtagata ctgtaaataa
    13801 aaaaactgga gaaaagaaaa atatatatac actaagtttt tatgataaag agtttacaat
    13861 gagaaaaaat ataaaatata aagattatgt tgttgaaaat aaagaaaaaa aactatcaat
    13921 aggaaactat acttttccaa taaagataaa aacgagtact ttttatgaaa caaaaaaggt
    13981 tgaagtaaaa aggaataaag aagagttaaa aaaagaatta tctgaaaaag ctttaaaaga
    14041 gttagaatac ataatcccag cttcggctag aataatagat gtaaaacata actttaaggt
    14101 taataaaaat atgttagaat atttaataac agttcaaact agtgaaaata ttgctaaaat
    14161 ttatcctctt agtaagtcag aagcagaaag gtttataaag gaagaaagta aaccagatga
    14221 aggtgaagag gaagttcctt ccaatccaga aaaaagacca ttaaatgata taagaaatga
    14281 gtttgatgag gataataagg ataataaaga ccaaaacaat tctgatgaaa ataatagtaa
    14341 tcaaaatagt aataatagtc aaaataataa tagcaataac aactaataaa attaaactta
    14401 aaatcttagg aggactaatt caattgataa tacaaaagaa atttacaata gcagatggta
    14461 actttgaaag agagttattt ggcaactttg atgaaaatgt aaaattaata gagaagactt
    14521 taaatataga tgtaatactt agagaaggca atataatttt aattggagaa gaaaaaaatg
    14581 tagattctgc attaaaactt atgaatgaat tacaccaaac tgtatcaaat ggtaagcatt
    14641 tagataagca gagtatttct tattcattat ctcttttgct tgaaggaagt gaacaaaaaa
    14701 taaaagaact tgaggggaca atcgtcataa ctcaaagggg aaaagctgtt caacctaaaa
    14761 ctttaggtca aaaagaatat ataaaactta tagaaaataa tgatataact tttggtgttg
    14821 gacctgctgg aacaggaaag acttatcttg cggttgctat ggcagtaaaa gcttttaaaa
    14881 gagatgaagt tagtagaatt atacttacaa gaccagctgt ggaagcagga gagagtctag
    14941 gttttttacc aggagattta aaggacaaag ttgacccata tttaagacca ctatatgatg
    15001 ccttatttga aatgttgggt gctgataaat ttaataagta tttagaaaga ggtactattg
    15061 aggttgcacc acttgcattt atgagaggta gaacacttga taattcattt ataatattgg
    15121 atgaagctca aaatactact tctgaacaaa tgaaaatgtt tttaactaga cttggatttg
    15181 gctctaaagc tgtagttaca ggagatgtaa ctcaaacaga tttaccacaa aataagaaga
    15241 gtggtctaat acaagctaca gagatcctta aaggtgttcc aggtattggg tctataatgc
    15301 taacagatag agatgttgta agacatgagt tggtacagag aataataaga gcttatgaga
    15361 agcacgacaa aagagaagaa tttaaaaaag aagaacgtaa aaaagtgaaa atgcaggaaa
    15421 agactttcaa aagaaagtaa aagtgtagta atatagatat atagcattat taatgaataa
    15481 aaagtaggtg tagtgaatgg atttgatact agatgataga caagataaat tagaagtaag
    15541 tgaggagtta attgaaaaga taaaggatat aatcatagaa tgtttagatt atgaaggata
    15601 tgatgataat tatgaagtga gtctttcttt tgtagataat aaagagattc atgaattaaa
    15661 tagagaatat agaggagttg atagagtgac tgatgtttta tcatttcctc ttttaagtga
    15721 tgattttgag gatgttgagt tagaagaaga atccctaggt gacatagtag tatctcttga
    15781 aagagcctta gaacagagta tagagtataa ccatagtttt gaaagagaag tatgtttttt
    15841 aatatgtcat agtatgtttc atcttttagg ttatgaccac gatacagatg aaaatacaaa
    15901 agaaatgaga gaaaaagaag aacacatatt aaataagtta aacataacaa gggagtagtt
    15961 tttatgaaac cagaaaaaac tcgtcaaggt ataattaaag catttaatgc agctatagaa
    16021 gggatattgt atacatttaa atttgaaaga aatatgaaaa tacattattt aggttcagtt
    16081 gctgttctta taataagttt gttttttaac ttttcaaaat tagaaatgat aatgttactt
    16141 atgtccatat gcttagttgt agttgccgaa atgtttaata cagctataga aaaagctgtt
    16201 gatttagtaa ctgatgaata tcatgttctt gctaagatag caaaagatgt tgcagctgga
    16261 ggcgttctag tggcagcact aaattcagta gtagttggat atattttgtt ttatgataaa
    16321 ttgacagata tatctggaat attaatttat aaaataagag aatcagaatt acatataacc
    16381 ttgatatgta tattattggt tcttatagct gttgtagttg taaaagcatt gacttctaca
    16441 ggtactcctc taaaaggagg aatgccaagt ggtcatgctg ccttagcatt tgctatagca
    16501 actgcaatta cacttatgac tgaaagagtt gttgcctcta ctcttgcata tataatggct
    16561 gtattagttg cccaaagtag aattgaagga aaaatacata ccttttggga gactattgct
    16621 ggagctttat taggtgtgtt gatagctata ttagtatttc agcttggaat gttctataat
    16681 taaaataaat gtacataaaa tatttaaaat aaaacaaatc tgtgctaatt aaatttttat
    16741 gatataatgt agagtattaa ataaaaataa cttttaatta ttgtatacag gaggagttgt
    16801 tgtggataac atagaattgt taaggttggc agaagatgcc agacaacatt cttatgctcc
    16861 ttactcaggt tttagagtag gtgcagctct tttaactaag agtggtaaag tttatactgg
    16921 atgtaatata gaatgtgcat cattaggtgg aacaaattgt gcagaaagaa cagctatttt
    16981 taaagcaata tcagagggtg ataaggatat ctataaaata gctatagcaa gtgataactc
    17041 agaaaataat gagcaaacat atccatgtgg aatatgcagg caggtaatta tagagtttgg
    17101 ttctgatata aaaataataa cgggatatac taaaggagag gtgtttgagc atagtataaa
    17161 ggatttgttg ccaaactatt tctctggaaa tgatttaaaa taaatttaaa agtataaata
    17221 aatttaagta attaaaacaa gaagataaaa agttaggaga cagttaatgt tcaaatcagg
    17281 ttttgtcagt atagtgggta gaccaaatgt aggaaaatct actttaatga ataatgtagt
    17341 tggagaaaaa atagctataa tgagtgataa gcctcaaact acaagaaata caatacaagc
    17401 agtatataca gatgaagaaa tgcagatagt attcttagat acacccggta ttcacaaacc
    17461 aaaaaataaa ttaggtgaat ttatggtaaa ggcagcaaca gaagctttta aaaatgtaga
    17521 tttaatatta tttgtagttg atgattctaa aaaaataggt cctggagata gaaagataat
    17581 agaggattta agaagtgtta agacaccaat aattttagtt gtaaacaaaa tagaccaact
    17641 agaccaaaaa gatgagctat ttgatataat caaaatgtat gatagagaag gtatttttaa
    17701 agaaatagta ccaatatcag cattaaaagg aaagaatacg gataccttaa taaaagttat
    17761 acaaaattat ttagaagaag ggccaaagta ttttccagat tatatgatta cagaccagcc
    17821 agaaagagta ttaatagcag aacttataag agaaaaagtt cttcactatc ttaatgatga
    17881 aatacctcat ggtgtagctg ttgaaattga aaaaatgaaa gcgagaaatg ataaggaaat
    17941 agtagatgta tctgctgtaa tatactgtga aagagattca cataagggaa taataatagg
    18001 aaaaaatggt aggaaactaa aaggaatagg taagtcagca agacaagata tagaattgct
    18061 tttaggttca caaataaatc ttcaattatg ggttaaagtc aaagaaaatt ggagaaattt
    18121 acaaaattat ataaataatt ttggatataa tgataaataa aggtgggtta tatggatagg
    18181 aaactggatg cttcccaaga tttattatat gaagtaaaat cattaattga taataataaa
    18241 gtattggagt taagagaatt aatagaggaa tatcatataa ttgatatatt cgatataatg
    18301 gaaaatttag aggaagacat gaaaattcaa ttatttgaag tacttccttt agatatggca
    18361 tcttctatat tagaagaagg tagtgtagag ttttttatta gtattttatc taaactggat
    18421 gtagaacact cgaaaaatat acttgaactt atgtctcttg gagatatggc agacaagttg
    18481 agtgaacttg aagaagaaga aagagaacac ataataaatc ttttgaatca agagaatgcc
    18541 gattatgtaa aagagttact attctatgat gaagattctg ctggtggaac aatgaccact
    18601 ggatatattt ctataaataa agatatgaca gctcttgagg ctatagacca tatgagagaa
    18661 gaagctgaag aagctgaaac tatttattat atatatgtgg ttgatgatga agaaaaacta
    18721 gttggagtat tgtcattaag agaattaata atagctagag acgcaaatat agtagaagat
    18781 ttgatgagtg aaaatataat ctctgtttat gtagatgaag atagagaaga agcagtaaga
    18841 ttagtatcta aatacaattt aatagcaatt ccagtagtag acagacaaga aaaattaaaa
    18901 ggaataataa cagtagatga tataattgat gtaatggaag aagaagcaac tgaagatatg
    18961 tataaatttg caggaagttc agaacatgaa agagaagttg ctgaaaaaga aaaccctaca
    19021 ttgagagagc aaataatatc agcacttaga ggacgattac cttggttaat tattaccttg
    19081 gttggagggt tgttggcttc gttaatactt tctaacttag actatataat gaatcctgta
    19141 tatgctccat tagtattttt tatacctgta gtaattggta tgggtggaaa tattggaact
    19201 caatcatcat ctgttacagt aataacatta tctaataagg atttaaattt tagcaatgtg
    19261 gttagagaag gtattgtagg tattattaca ggtcttttgt gtagtataat aacaggtatt
    19321 gtaatttact ttgttatgag aaagttagac attgtattaa ttgtttcaat atcattattt
    19381 ataaatatgg ttttaggtgc aacaataggt gcgtttatgc ctgttttatt aaaaaaaatg
    19441 gatgcagacc catctacagt ttcatcacca attatatcta cagctcttga tataactggt
    19501 atagcagttt actttataat aacaacggca ttattgtcaa aaattgttta ataactttat
    19561 gtatgattta tcctcttctt actaaaaata taagtataaa tgtaagaagg gggtttttta
    19621 aaaatgaaca atatcagttg ggaagttttt aaaaaaacag gtagtataga tgcatattta
    19681 tatttctgtg attgcaaaaa catacatgaa gaaattgaag aagtaaggga gaaaaaagaa
    19741 gacgatgata atcctgaaca cccaggggat agtacttaaa gctataaggt ataaggaaag
    19801 tgacataata cttacactat ttacaagaaa gcttggaaaa gtatctgcaa tagcaaaagg
    19861 agctaaaaaa aataagagct ctttgctttc atcatcacaa ttattttctt atagcaattt
    19921 taccttaaaa aaacaaggta atatgtacaa ggttactcaa agtgaaataa taaaaagttt
    19981 ttataatata tcctatgata tagaggcatt ttcttatgct acatatatta caaaattagt
    20041 tgaaaattct atacttgaaa atcagactaa taataggcta tttatattac ttgcgcagac
    20101 tctgtatttg tatacacagg ataatacaga caataggttt ataacagcag cattcgagtt
    20161 aaaattttta gactatatag gatttaaacc tatagtaaat aaatgcatta attgtgaatg
    20221 taaaatttta caaaattctg tgtttaatat ctacgaaggt ggtatactat gtagtaagtg
    20281 tagtaaactt tttgataata atataaaatt agacttaaca actataagtc ttatggaata
    20341 tgtattaaga aatgatattt taacatgtag taaagctaaa gtatcaaaat atataacaca
    20401 tgaacttgag aatattctag acaagtattt gaaagtttat gttgataata ttaattttaa
    20461 atcattacac gtattgcaaa gtgtaaaaaa taataaggga gtggataatg atgagtagta
    20521 atataactat tgaaatggtt gattcagtct ttgaaagagt tccaggagca acttatgcag
    20581 aagcaaaaga agcattagta atgtgcaatg gagatgtaat tgaggcagta atatatttag
    20641 aaaataaaaa aaatacttgt aattgtaaag caaaatctgc taaagaaact atggaagaag
    20701 tatttggcaa agatggagaa aatataaagt ttcaattaaa agagcttctt agaaaaagta
    20761 gtgtagtgag aataatagtt gaaaaagatg gaaaaactat gatgaacatt cctttaacag
    20821 ttggagttgt tggattagct tttgtaccat tagctacttt agttggatta tcagctgctg
    20881 ttataagtaa atatcgtata aaagttcaaa atgaagaaga tggagaaatt gtagatttag
    20941 gtgaattgaa tgaagaaaaa cttcacgttt tgaagaatat gataactaat gcagcaaaag
    21001 atgtgaagga tgtagtagtt gacaaaaaag aagatgacaa agatgtaact gctgacctta
    21061 tgaaagaaga atctgaaaag aataaagaag acgaagacga aaataaatag atataaagtg
    21121 acttttaaaa aatgaagaga agataattat aagaattatc actaacattg acaaatttta
    21181 tagaatttga tattctaaaa gttgtagaag aactattaaa atagcctttc gtgtagacga
    21241 gaggctttat tgttatagga gggattttta tgaattttca agagatgata ctggcgttgc
    21301 aaaaatactg gtcaaagcaa ggttgtatca tgatgcaacc ttatgatatt gaaaaaggtg
    21361 caggaactat gaatcctaat acttttttaa gatcattagg acctgagcct tggcaagtat
    21421 gctatgtaga gccttcaaga agaccagcag atggaagata tggtgaaaac ccaaacagac
    21481 tatatcaaca tcatcaattc caagttatac taaaaccttc tccagataat atacaagaat
    21541 tatatttgga aagtttaaaa gagattggaa ttgacccaag tgagcatgac ataagatttg
    21601 ttgaagataa ctgggaagct gctacagttg gtgcttgggg acttggatgg gaagtttggc
    21661 tagatggtat ggaaataact caatttacgt attttcaaca agtaggtaat attgaatgtg
    21721 agcttgagac aggagaaatt acatatggat tagaaagatt agctatgtac attcaagaag
    21781 ttgatagtgt ttatgattta aaatggaatg ataaaataac ttatggtgaa gtatttaata
    21841 aagctgagta tgaaaactca atgtacgcat ttgaattatg tgatgcagat atgttgttta
    21901 atctgtttga tatatatgaa aaagaagcat taagacttat ggaaaatggc cttgtaatac
    21961 cttcatatga ctatgtgtta aaatgctctc atgcatttaa tacattggac gcaagaggtg
    22021 caataggagt tagtcaaaga gcttcattta taggtagagt tagaaatatg gcaaagactg
    22081 ttgcagaaac ttttgtaaaa caaagagaag aaatgggatt ccctctttta aaggacggtg
    22141 acaaataatg aaaaattatc ttttatttga aatcggtgtt gaagaaatgc catcaagatt
    22201 tgtaggcagt acactagaac aattaaaaaa caatcttagt aaattatttg atgaaaatag
    22261 aatagctttt gataaaataa atgcgtatgg gacaccaaga agacttactt tagtagtcga
    22321 aggattgagt gatagacaaa gtgatttaga agaggaaata aagggtcctg ctaagaaaat
    22381 tgctgttgat gcagaaaata atttaacaaa accagcatta ggatttataa aaagcaaagg
    22441 attaagcgaa tctgacatat attttaaaca agttggaaaa gaagaatata tatttgcgac
    22501 tataaagcaa gatggaaaag aaacttcaga agtactaaaa gacatattac cagagactat
    22561 aaaatctgta gtattcccaa aagctatgcg ttggggagga aaaaatctta aatttgcaag
    22621 acctataaga tggatagttg cattgttaaa tgataaagta ttagagtttg atttagaagg
    22681 aataatatct tctaatgtaa caaaaggtca tagattttta ggtgaaagta caatagaagt
    22741 tgattctata gaagattatt ttgaaaaatt agaaaaaaat tatatagttt tagaccaaaa
    22801 caagagaaaa gaaatgataa gaaaacaatg tatagaagta gcaaattctt taggtggaga
    22861 agttgaattt gatgaagatt tacttgaaga ggtaacttat ttagttgaat atccaactgc
    22921 tttttatgga gaatttgatg tggattatat aaaactacca aaagaagttg ttataactcc
    22981 tatgaaacaa catcaaagat attttccagt acttaaagaa ggaaaactgt tacctaactt
    23041 tatagctgtt agaaatggtg attcttacag aatagacaat gttaaagctg gaaatgaaaa
    23101 agttttagaa gcaagacttg cagatgcttt atttttctat agagaagata ctaagagaaa
    23161 cttagaaagc tacatagaaa aattaaaaac tgttgtattc caagtaaaac taggaactat
    23221 ttacgacaaa actttaagac ttgaaaaatt aagtgctgat atacttgata gtttaggttt
    23281 agtagatgaa aaggcagata ctataagggc tgctaaatta tctaaggcag atttagttac
    23341 tggaatggta ggagaatttg atgaattaca aggttttatg ggaaaagaat acgcaaaagt
    23401 tggaggagag aatgatgttg taagtgaagc tatttttgaa cattatcttc caagatttgc
    23461 aggagatata cttcctaaga ctaatgcagg ggttgcctta tcaatagctg ataagttgga
    23521 ttcaatagca ggtttctttg ctataggaat acaaccaaca ggttctcaag acccatatgc
    23581 tttaagaaga caagctttag gtatacttag tatacttatg gacagaaaag ttgctgtgga
    23641 tataaaagta cttattgaac atgctttaga taattattct gaattagatt ttaataaaga
    23701 agaagttgtt gagcaaataa tgaatttctt caatgagaga gtaaaaaatc tatttaaaga
    23761 tttaggaata agatatgatg ttgttgatgc tgttttaagt tctgatataa atgatgtttc
    23821 tgatatgcat atgagagctt tagagcttaa taattggcta gaaaaagatg aattagtgga
    23881 gatgcttact gcatttaata gagtttctac tctagctcaa aaagcagaaa gtgataaaat
    23941 tgatgaatct ttattaaaag aagatgctga aattagactt tacaatgaat ttaaacaagt
    24001 aaaggtaaaa gttaatgaat tattaaagga taagaaatat ggtattgctt tagatgaatt
    24061 tgcatcttta agaccagtag ttgataattt atttgataca gttatggtta tggataatga
    24121 tgaagctatt aagaacaata gacttgcttt acttaaacaa gtatatgata ctatgctaga
    24181 aatttgtgat ttatctaaaa ttgtttataa ataaaattta aactatttat aagaaataag
    24241 gctgtctcaa aatagagata gtcttatttt tcattgttga gatgatgaaa atatatttga
    24301 tttcatagaa aaagagtgtc tcataaacta aaaagttcat tttgagacac ccatgctttt
    24361 tgtaagtaaa tataataaat tatattttat acttatcagt tattttgttt aaaatattat
    24421 catttgaatt tacccattca taaaaattgc ctgatgatgc gtccgatatt ttataaagca
    24481 tttcaggaat atcactagct ttaaaatctc caagtgattt tcccaatcta gtcttaccta
    24541 tttcaaaact gcctccaaca aataattcaa atgcatctgt agatatacca tcaacattct
    24601 tctttttacc acataaacct atgctaccaa cttgatgaac accacatgaa tttaaacatc
    24661 ctgatatata taacttaggt gctttattta aaatttcttc attattttgt aatctaaaat
    24721 aatctatgat ttcatgtaac attttctgac tattttgtat gcccatttga caaattggaa
    24781 cacctatgca agatatactt tgttctaatt gagaattaca actaatagtt ttacttattt
    24841 ctaatattct ttttgcttca tttccattta aatttaaaat atataatccc tctgtcattc
    24901 ctagtctaat cataggattt tcaacattat ctaattcttt aagtaaagta cttaaatcct
    24961 ttgttaacaa aatacctcca actggatgta tatatacagt gtataaacca tcctgttttt
    25021 gaggtattag tctagaatct tgtatatcta ttttaactcc aggtttagag taatctattt
    25081 cttcaatatt gagttcaaga ctaccatttt ctttttctaa tttatagtat tctttaaatt
    25141 tttctaagaa tagttcttca ccaagtgatt cgaccatata tctaacccta gctctgtttt
    25201 tattttcata atttccataa tccataaaga atttaatcat accttcaaca caatataagg
    25261 cgtctttcgg ctttataagt tcatcaagtt ctaaagcaac tttgggttgt ttacctagac
    25321 ctccacctaa gaaaactctg aaatatggtt catcattttt caaagtagca acaaatccta
    25381 agtcttgtat actacaatga gcagtatctg tgtaacaatt agaataagaa acttttaatt
    25441 ttctaggtaa atggtatgta gtagcatttt tgataaaata tttatcagta gcaactgcat
    25501 atggagtaac atcaaagact tcactagggt caactccaga taatggagat aatccgacat
    25561 ttctaggata attaccacca ccacctctag tgaatatatc attttttatt ccttcttcca
    25621 tgatatcaac aattgaattt atagataaat cgtgtaattg tatagcttgt ctagttgtta
    25681 agtgtatctt atctaagttg tgtttaatag ctatttcata gattttatta agttgatact
    25741 gagataaaac tccagcagat actctaagtc ttatcataaa agattttttg tctctttgag
    25801 cataaacacc atatccacca gaaaatccct tatattgcat tttatttatt tctccattta
    25861 aaaattttga agaatattct ttaaaattag gtagttcatt taacaatatc tttttaaaat
    25921 tatccattat ttcacctcat tgttagtctt gtataaaaat atatctattg tataatagat
    25981 atatatatta ttatctagtc aggataaaaa tataacagaa taattctatt aaaagtaaga
    26041 ataataagga catagtgagt attttgtttt tattttacaa attaagtata atatttttgt
    26101 tttataaaat ataattaaga taaatagata attttgtaat tttaatatat aatatttagt
    26161 agagtgtggg agtagcactt aatatttgca ggaggagttt ttgtatatgg gagaaataat
    26221 aaatgcatta gatagagccc tagacataat tttgctgtta tatcatgaaa agagagaaat
    26281 gggaataact gaaataagta aggctatggg agtatataaa agtactgtac atagaacttt
    26341 ggttactctt gaaaacaaag gttttgttat acaaaatgca gagaatggta agtattggct
    26401 aggaataaat ttatatgcaa taggtatggt tgtgggagaa aaaatgtcat tgactgaaat
    26461 agtaaaacca tatacgaaaa aattaaatca agaatttaac gaagtagtta atgtatctat
    26521 attagaagaa agagctcaag attctccaag aagtatcata atacataaag agtatggttc
    26581 aaatcaatta ctttcagtaa atccatccgt tggttcaagt agtgaatgtt attgttcagc
    26641 agttggtaaa tgtcttatgg catttaatga ttctatagat tttgaaaaat atagaaaaac
    26701 accaatacac aagtatacag aacatacaat tgataattgg gatgatatga tgcttttttt
    26761 agcaaaaata aaagaacaag gatatgctat agatgatgaa gaactagaac atggactaac
    26821 ttgtattgga gcacctatct tagataaaaa taataaagct attgcagcca taagtttgtc
    26881 aggtccaact ataagaatga gagaagggga ctttgagtat aagattaaaa gagttataga
    26941 aactgcaaaa agtatatctg aactttttag atgattttta atctcgataa taaaaatagg
    27001 ctatatttaa attgttattt gtaaatatca gtttaaatgt agcctatttt tctttaatct
    27061 aaaattaaat attcttaaaa tttaaaatgt tattgaaata tataagcgaa tgtgttatct
    27121 tttaattaag caataaaaat agaacaaggt tctatactat agaacaaaat tgatgcatat
    27181 atagtattta tacaaaatat aaatattata tatttaaaat taagtaaaaa tattacataa
    27241 aggggagatt tgagaaatgg aaaaagtcaa gttgagtgtt gaaagatgta agggatgcta
    27301 tctttgtatt gaagcttgca aaaaagatgc aataagtctt tctgactaca caaataaaaa
    27361 aggctttgta actattaaag tcgatgaaga aaaatgtatt caatgtggcg cttgttatac
    27421 aatgtgccct gatttagtat ttgagatatt ataaattatt tttattagag gggagaaaag
    27481 gtatgcaaag tttattaatt aaaggaaatg aagctttagc agaaggtgct atacgtggtg
    27541 gctgcagatt ttatgcaggt tatccaataa caccacaatc agaaatatta gaaatgatgg
    27601 catggagaca aaaagaagtt ggaggagtat ttatccaagg tgaatcagaa atagccagtg
    27661 taaatatggt tatgggagca agtgcacttg gagcaagagc tatgacttct tcatctggtc
    27721 caggattttc attaaaacaa gaaggtattg catattgggt atcagctggt ttgccagcag
    27781 ttgtagcatg tgtgcaaaga tatggtatag gtgatggatt tataggagct ggtcaagata
    27841 attattggca agcagtaaaa ggcggtggaa atggagatta tcatttaatc gtgttagcgc
    27901 ctaacagtgt tcaagaaaat atggatatgg catatgaatc ttttgaattg gctgaaaaat
    27961 atatgcatcc agtacttata ctttctgatg ctacaatagg tcaaatggta gaaccttgta
    28021 tagcaccacc aatgaaagaa tacgatatgg ataaagctcc atgggctgca aaaggaacac
    28081 ctgtaggaga aaaaaataaa gtaataactg atataacata ttttgaagac caagatacat
    28141 ggcaaaaagg gtatatagaa aaaatgagaa aagttcaaga agatgaacaa agatgggaag
    28201 agatagaaat agaagatgct gaagtggtat ttgtggcata cggtatttca tcaagaatag
    28261 cagaaggtgc agttagagat gctagagcaa aaggaatgaa attaggtcta ataagaccaa
    28321 aaacattgtg gccttaccca agaaaagcat ttaagaaatt aagtgattca ttgaagggac
    28381 ttgtaacagt tgaaatgaac atgatggcac agatgaagga agatgtaatt atagcatgtg
    28441 ataatagatt tccagtatat tcagtagcaa cagctcaata tatggcagaa gtaaatcaat
    28501 taatagattt tgctcaacag attatagatg gaaaagctaa gcaagaggag gtattttaat
    28561 tatggctaag aaagcaccag caataatgat gtgtgaaaat atgttttgtg gaggctgtgg
    28621 acactctata gtcgatagaa ttattggaga agtattaaca gaaatggata tatgtcaaga
    28681 tacaattata tgttcagata taggttgtaa tcatatgttt caatttagta tgaatgtaga
    28741 tgttgtcgtt ccacctcatg gtaaaatggg tgcagcaatg gcagctatga aaagagttag
    28801 accagataaa tatatattta caatagctgg agatggtgga gcttatgcga tagggcttgg
    28861 ggaaactatg tcagctgcta ctagaaatga taatgttata ttccttgtta tgaacaataa
    28921 tatgtttgca atgacaggag ggcaaatggc tccaactact atagaaggtc aatatacagc
    28981 ttctactcca gcgggtagaa attacgcaga tcatggttca acatttgatg ttgtaaaagt
    29041 tatgggaaat ttagatatag catatctagc aagaggaaca ataactaacc ctaaagaaat
    29101 aaatacaaca aaaagataca tcaaaaaagc tctagaaaaa caaaaagaaa agaaaggttt
    29161 ttgcttaata gaagtgcttg taccatgtcc aacaaactgg ggattaaagc cagtagatgc
    29221 tatgaagaga attgaaaatg aacttgttcc aaagtatcca cttggagaat ttattgatta
    29281 gggaggaaat aatatgttga atgaaattat atgtgctggt tttggaggac agggagttct
    29341 tacagcagga aaaattataa tgtatgttgc atataaggca gaaaagaaaa ttacatggtt
    29401 cccatcttat ggaaatgaga tgaggggagg aagtgcaaat tgcaatgttg ttgtaagtga
    29461 tgaaaaaatt gcaaatcctt gtgtaaaaaa tccagatata ctattgggaa tgaacagcgt
    29521 atcagtagat aagtatgaaa gtttaatgaa aaaaaatggt tatatgtttg tcaatgaatc
    29581 actagtaagt aaggatagaa agtacagaga agacattaat gttataaaag tacctgttac
    29641 tgaaatagca caaaatttag gcaatgaaaa agctgctaac atttgcatgt taggtgctat
    29701 ggtaaagagt ttggatttat ttacaaaaga agaatttgaa agtggtatgt gtgaatactt
    29761 tgaaaatcaa ggcaaaggta aattcaattc taaaaatgta gaagcatttg aagcaggata
    29821 cgactacgaa tgaatatttt aaatatttaa aataattatt gaaatactta tttttatatg
    29881 ttagtattta attaataaaa tatagaacgt cgttctggac aataggacga agtctttagg
    29941 ccggaataca agaacgacgt tctgtatagt agaactaggg ggtgttaaat tgaaagtttt
    30001 agtaataaat cctggtggta catccacaaa aatttctgtt ttccaagatg aaaatgaaat
    30061 tttgaaaaaa aatataaccc atacaagaga agatttaaaa aatttttcta aagtatttga
    30121 tgaatatgat tatagaaaac aactgatagt agatatttta agtagtgaga atcatagtat
    30181 aaattctttt gacgcagtag ttggtcgtgg tggacttatg aaggctataa aaggtggtac
    30241 ctatactgtg agtgaagaaa tgattgagga tatgagaaat gaaataaatg gggaacatgc
    30301 atcaaattta ggtgcattat tagctaaaac tatagctgat gaaataggag tacaatcatt
    30361 tgtagtagac ccagtttctg tagatgaatt tgatgatgta tcgaggatta caggaatatc
    30421 agacatagaa aaagcaagtt ggttacatgc attaaaccat aaagctgttt caagaaaaat
    30481 tgcacaaaaa ctagggggaa aatacgagga ttataacttt attgtagctc atttaggttc
    30541 aggaatatcg attgtagcac ataaacaagg caaaatgatt gatggaagtg gtggtaggtc
    30601 tgatggtcca ttttctccag aaaggagtgg tggattactt gcatatcctc ttatagaatt
    30661 gtgttactcc ggaaaatata ctcatgatga aatggtcgca aaagtaagtt cgattggggg
    30721 aatgtacgat tatttaggaa caaaggacat gatagaaatt gaaaacagaa tcaaggaggg
    30781 tgatgaaaag gcaaaactta taatggatgc atttatttat caagtagcaa aagaaatttc
    30841 tatgtatgga gcttcacttt cagggaatgt agatagagtt atcttgacag gagggatatc
    30901 tcactcagaa atggtagtca aaggagtagc agaaaaagtt tcatatctag ctccaataga
    30961 gatagtacca ggagagatgg aaatggaggc acttgctcta ggagcactta gagtacttaa
    31021 tggagaagaa atagcaaaaa cttattaata tttaggagaa agagtatgtt aaaagatttt
    31081 aataatttat tagaagaggc taaaaagctt gaacctgtta ttgtaagtgt tgctgttgca
    31141 gaagacaaag aagtattaaa ggctgtgaaa tcagcaacag atttaaacat tataaagcca
    31201 attcttgtag gagacaagga taaaatagaa agtatatcaa gagaaattgg attaaaaggt
    31261 catgaaataa taggttgtca aaatcccgat gaatcagtta aaaaagctgt agagatagtt
    31321 aaaaataagg aagctaaagt tcttatgaag ggattagtaa atacaagtgt ctatatgaga
    31381 gctatattaa ataaagaaac gggtcttaga acaggaagat tattaagttt gcttgcagta
    31441 tatgaattac ctcaatatca taaacttctt tattgtactg atagtggaat aaatgtatcg
    31501 ccaaacttaa atcaaaaaaa agatataatg acaaatgcac ttcttactat gaaaagtata
    31561 ggcatggaaa atcctaaaac tgcgatactt actgcaaatg aaatggtaga ccctaagata
    31621 caatctacag tggatgccaa cctacttgta gagatggaaa aatcgggaga aataccaaag
    31681 tgtatagtgg aaggtccaat agcatttgat gtagcatttg atgcacatgc agcagaacat
    31741 aaaggtatta aaagtaatat tgctggtgat gttgatttat tagtatttcc aaatatagaa
    31801 gcagggaata tattaggaaa gtcatggctt agatttaata aagctaagtg ggcaggtata
    31861 gttttaggag caacaaatcc gataatttta ggttcacgtt ctgacacagc tgaaataaaa
    31921 ataaattcaa tagcattagc gtgcctagca tcacaataag aaattattat taaggaggag
    31981 aaagtattat gaaatatgca aaaagaatgg atatggtaaa agcttcagct ataagagctt
    32041 ctcaaaagaa aatagctcag aaggtggcaa gtggtggaac tgttatatct tttgctgcag
    32101 ggcttcctga cccaaattta tttccaatag aagagataag tgaaataact caaaaagtac
    32161 ttaatgaaag gggaaaattt gccctagcat atggacctac taaaggtgaa gatgagttgt
    32221 tagatctatt agtaaaaaga atgaaagaag aagaaaatat tgatacaaaa gcagaaaata
    32281 ttataataac tactgggtca caacaaggga tagcattaag tgctatgatt ttactagaaa
    32341 aaggagatat agtagttaca gaaaatccaa gttacttagg tgcaataaat gcatttagac
    32401 cttatgaatg tgatttttta ggagtagata ctgatgatga aggaatggta acagatgatt
    32461 tagataaatt attatctgaa aattctaaca taaaggtaat ctatgtaata ccaacatttc
    32521 aaaatcctac aggaaaaaca tggtctttac aaagaagaaa agattttatg gaagtcgtga
    32581 ataagtatga tgtcatagta atagaagata atccttatgg agaaataaga tttacaccag
    32641 agcctctacc tacacttaaa tctcttgata ctaaagataa agtattatac ttaggttcat
    32701 tttcaaaagt attatgtcca gggtttagag ttgcttggat gtgtggtaat gtagacatca
    32761 tagataaggc agaactttta aaacaaggta tagatttaca gtcaaatcaa ttttcgcaag
    32821 tacaagtaat agaattttta aagaaataca acttaaatga acatatagaa aaaataagag
    32881 cagagtataa gaaaagatgt ctgctaatgt tagatgctat gaagaaacat ttcccagagg
    32941 aagctaaata tacagaacca gatggaggaa tgtttatatg ggttgaactt cctgaaagta
    33001 taaatgtaga tgatttattg gataaagcca ttgatgctgg agttgcttat gtttctggag
    33061 agtccttctt tgcaaataat ggtccaaaaa atactatgag acttaactat acaacaatgt
    33121 cagaagaaca aatcgttaaa ggtgttgaga tacttgcaga agttataaaa aaagaactca
    33181 attatgcttg tgaataaata taaaaagtga gggtttaaat atgggagaaa aagaaaacgg
    33241 tataaagttt ggaaagttaa tgtttcaact tgttattata gcaatatctt gggaattagt
    33301 ttatattata ccatttatcc aatatacatt atatgatcca atcctaaaag cattagaatg
    33361 tacaaacact caactaggtt ttctacttac aatttatggg ttaggtaata tatttggagc
    33421 tcctatagga ggctggttag cagatagatt tgattataga aagataattt taggttctgt
    33481 atttcttaat ggagtagtat catttttatt tgcatttaat atgaactatc catttgcagt
    33541 tgctacttgg gtaggttgtg caatcacatc attagttatg aactatcctt ctatggtaaa
    33601 aatacttaga gttataggaa aagataatca aggtaaagtt tatggattca atgaagctat
    33661 ggttggagtt tctggcgtag taatgggagc aatattctta tatatttata catgcttttc
    33721 aactcctgta ttgggtatga gatgggtaat gatatcttta ggaatattat caatagtgat
    33781 gtgtccagta ttatggtttg taattaaaga tgtagatatc agagaagaca aagaagaaga
    33841 agcaagtgaa aaaatgtctg ctggcgattt tatgacagta ctaaaatcac caaacacttg
    33901 gctagtagga ataagcatat tctgtgtata ttcattcaca gttacaatgt cttattttac
    33961 accatatata acatcagtac ttggaggttc tgtggcattg tctggggcat tagcaataat
    34021 aagacaacat ggtctaaaat tgtttggagc accatttgga ggatattgtg cagataaagt
    34081 aaaatcacct acaaaagtac tactaccaat atatgtattt ggtatagcag taataatttt
    34141 attcctagta ctacctgcat ctactccaat gactatcttt atagctttaa catttgtagt
    34201 aggtatatta ggttacatgg gaaaaggtat atactatgca gttcaagatg aagtaaaagt
    34261 tccagttaaa tattcagcaa ctactatagg tatagctgca gctttaggat tttcaccaga
    34321 tgtattccaa tttgcattaa taggacactg gatagatact tatggcaata aaggttacac
    34381 atatacattt atattccaga tagcaattct aataattggt atactatctt gtttatatat
    34441 attaaaagtt aagaagaaaa gagaaagtaa gttagaagca taaatattgt aaaaatacca
    34501 aattattaag ttttatagca atacttaaaa tttaaagtgc aacacaccaa aatgttatca
    34561 agttttctag gttttagtat aaagttaccc ctaaaggtct ggaattgagt agcaattatc
    34621 atctatttat atatttacat aaacctattt aatttaaatt aaaagaattt caaaaatagg
    34681 tggtaattgt actcaatttt acacctcata ataaatacga aaatttaaaa tctaactata
    34741 tactattcaa ttatatatta ataattgtat atggtactat ttatatagta acagtttcag
    34801 gcttttcatt acatgtattc caatttatat tgtttgatta tttgtcaaat acatatcgtt
    34861 aaaaagttta taaatttacg tttatatatc gattaatatt ctttgtttta gagatagata
    34921 cttatagctt gtggattaaa aataatataa atagaagata gattttttag atatattgag
    34981 ttgaagatta tatagaatgt tgaaacatag ctatttaaat tattgtctat aaatataaaa
    35041 tgaatggtgg tgagttaagt gaccgattta gttaacacca ttaatggaat tgtttggtca
    35101 cctgtattag ttgcaatgtg tttgtgtata ggattatatt tttcaatgaa attaagattt
    35161 tttcaaataa aagatgtaaa agaaatgttt actcttttgc ttgaaggaga tagctctcat
    35221 gttggaatat cttcgttcca aggttttgct acatctatgg caggaaggat aggaactgga
    35281 aatatagctg gtgtagctgt agcgatagca atgggagggc caggagcatt agtgtggatg
    35341 tgcataatgg ctacattagg gtcggcaact gcatttgtag aatctacttt agctcagata
    35401 tataaagatg agcatgatgg acagtacagg ggaggtcctc catattactt tgaaaaaggt
    35461 cttggttgga aaaaatgttc aattttattt tcagtggttg caatcataag ttatacattt
    35521 tttatgcctg gcacacaatc aaatactcta tatctagcaa tgaatcaagc atttggattt
    35581 tcaaaaatga caatagcagt tacatcttct attgcactag gtataataat ttttggagga
    35641 attaaaagaa ttggtttatt tgctgagaaa gtagtaccta taatgggtgg agcatacctt
    35701 attatgacat tggtaataat catagcaaat ataaatctag ttccaggagc tattatgaca
    35761 atgtttaaat ctgcatttgg atttggttcg gtttttggag ggatgttagg ttcagcaata
    35821 tcttggggag taaaaagagg tatatactca aatgaagcgg gagaaggttc tggaacttat
    35881 ggtgcagcag cagcagaagt gagtcaccca gccaaacaag gattagtcca agctttttct
    35941 gtttatgtag acacactatt aatatgtatg gctacaggta ttatgattat aataacagga
    36001 atgtataatg ttacagatgt ttacacaaca ttaccaggtg tagaaccagg tccacaatat
    36061 gtacagagtg caataaatac attacatcct caattaggtg atatttttat agcaatagtt
    36121 ttactactat ttacatttac aacattatta gccttctcat acatgatgga gaccaacgta
    36181 tcttacttag tgactagaat taaggcagaa aaacatgaaa agcacataat taatgtctgt
    36241 agatttatgc ttataatatg tgcagcaatg tgttgcttta tagaaccact tacaagttgg
    36301 gcacttggtg atatatgtat aggtgtatta acatatataa acttagttgg tatatttaca
    36361 ctaaaaaaac cagctataaa agcatattac gattatcaaa ggcagaaaaa gatgggagta
    36421 aaaaggagcg atagaacttt taatcctata gaattagata taagaaatgc tgagttttgg
    36481 gaaaatagat acttaaaaga ggataagcat gagttaaatt aaagttataa taaaatataa
    36541 aaattactaa ataaatttag tgggaggtaa gattggtatg aaagaaagaa taatacaagt
    36601 ggctgattca aagaaagaaa aaattctagg gctatgtcaa tctttatatg atgaaccaga
    36661 aattgctttg caagaatata aatctgctaa aaaaatatca gaatttctaa gagaagaggg
    36721 ttttgatgtt gaggaaaact tggcaggtat ggctacagct tttaaagcaa ccaagaaaaa
    36781 tggagatggt cctaaaatag catttatagc agaatatgat gctcttccag gcaatggaca
    36841 tgcatgtgga catcatttaa ttgcatctat gggagttgga gctggaatag ctctttcaag
    36901 tatactggat acttacaagg gagaagtaag tataattgga acacctgctg aagaaactgg
    36961 agatggaaag ccttacttga tagaacatgg tgtatttgat ggctatgatg cagcaatgat
    37021 gatacatcca aattcaaaaa cttgtgtaac acctgaaatt atagcaatag gaggtctaga
    37081 tttcatattt actggaaaag catctcatgc aggagctaag ccatataacg gaataaatgc
    37141 tttagatgca gtagtactac tatataataa tataaatgca ctaagacaac aattagtaga
    37201 tggaacgaga atacatggta ttatactaga agcaggaact gctgcaaatg taatacctga
    37261 tatgggaaaa gtaagattag agataagggc aaaagaacaa aattactttg atgaagtagt
    37321 agaaaaagtg aaaaattgtg ctagaggtgc tgcaatagcc actggatgtg aacttgaatt
    37381 ttatcacttt gaaccaactt gccaaggatt aaatgaaaat aaagttttgg tagacatatt
    37441 tacaaagatt atggaggaat ttggaatata tgaagatgaa caagtaatgt taggttcaac
    37501 agatatggga aatttaagtc aaataatgcc atgtatacat cctttgatga agttttctga
    37561 aaatggagaa gaactacata caaaagaatt tttggaggct tctataaatt catatgcaaa
    37621 agatagagta attgatggta taaaaatatt agctttaaca ggatttaatt tatttgaaaa
    37681 tccagagtta ttgaaaaaaa tgaaggaaga gtagaactta gactattttt aattatactc
    37741 tttaaaataa gaagagtgtc tcaaaatgaa ctttttagtt tatgagacac tcttttttgc
    37801 atgaaattaa atatattttt attattttaa caatgaaaaa gaggcttatc tgtttttata
    37861 taaccttttt taacttgtag cacaaaatat catgaatgat tacaattcga atgataaaat
    37921 cgattataag atatatagga ggggtacata tggaaacttt agaagtaaga aatattgaat
    37981 tgagtggtac aaattatgag ataggataca gactaggaga attggttgct aatatgccag
    38041 agataataga aggtcagatt aataaatcta atctggtaag caaaaaagaa gaaaaagaga
    38101 tgatagagtt gtttgataaa tattgtccag gtcttaatga agaattgcaa ggttttgctg
    38161 atgcaattca agtgaattgt aatcaaattt tatattatac tatgacttat cttaaaccag
    38221 gttgtagtca agttgcatta acaccagaat taactgaaaa tgggcatgta ctatttgcac
    38281 gtaatttcga tttctcacac aatatggagg attttgtttt atgtaaaact aaagtaaatg
    38341 gaaaatatgc acatataggt actaccgtta tgcaatttgg aagaggtgaa ggtatgaatg
    38401 aatgtggatt aggtgtaagt cagtcatcat gtggtattcc tgtaggcaat tcagatggtt
    38461 tgagaaaacc agcaattgta ggtttacagt tttgggctgt tattagatat ttgttagaaa
    38521 attgcaaaga tgtagatgaa gcattagaat atttaaaaga tatgccaatt gcatacaata
    38581 ttaatttatt gcttgcagat aagtctggaa acattgcact tgtggagact ttagatggga
    38641 aaaaagaagt aaatataatc aacagtttag aaagtaagag agaatatttt ttacactcta
    38701 ctaatcatac acatattgat aaacttcata aattagaacc acaatcaatg aaaaattcta
    38761 ttcatagata taaattaatt aaagaatata taaataaggc taaaaaaatt ggagagaaag
    38821 agttaatgaa tttattgtct ttaaagtatc caaatggctt atcttgtaat tactataatg
    38881 atttttttgg aactttaaaa agtatagtta tggatttaaa tataggaaag tttaatattt
    38941 tatggggtgg actagagaat aaatgggaga gctactattt aaaaaatgac attaaatcta
    39001 taacacagag gataaacata aatattgaaa aagcaccatc tgactttttt gatttcattg
    39061 aataaaaaat gtatttaatt attctaaata attaggctat ataaatcaac taaaagtttt
    39121 tatttatcgt attgaattag ttataatatt ttagtatagt aaaaaatagt gctattttac
    39181 atatttaaag agtttaagta gaagagaggt gccatattgg attacttaaa gtattttgaa
    39241 aaagctgtaa tgtatattga gaataattta catgaaaata taactgtaaa tgatgtggca
    39301 aaagaaactg gatattctta ttatcattta acacgcttat ttaagtctat gtttggtgag
    39361 agtgtaggaa gttatataaa aaaaagacga ttagtaagta gtacaaaaga acttttatat
    39421 agtgataaaa aagtgataga tatagctatt ggtagtggat ttgaatcttc ggaagcattt
    39481 agcagagcat ttaaatctat atacaaggtt agccctatag aatatagaaa aaatagaatt
    39541 gatgtatttg ttggtaaaaa gaaaaaatta gagttagatt ttatgagaca tcttgttgga
    39601 aatataacga ttaaaccagt tataaaagaa atagaaaaaa taaaggtaat aggtataaag
    39661 gataaagtaa ttttagaaaa taattcatta cctgacttgt gggagaaatt cagaaaagta
    39721 catcatattg tcccaaatac tttgccatca aagagagttt ttggaatctg tgaagcaatc
    39781 tctgaaatac acctagttag tgaaagtatg gaatttaatg agataatagg acttgaagtt
    39841 aatagttatg atgtgattcc aaattcattt gtttcaaaaa ctattaagga aggaaagtat
    39901 gctatattta ctcatactgg tagcttagat aacttagaca aaacttatga atatatatgg
    39961 ggtacttggt ttttaagttc aaaagaagaa ctggatataa gagatgattt tgaagtatat
    40021 gatgaacgat ttttaggtcc tagtaatgtg aactcacaaa ttgatattta tatacctata
    40081 aaataatcta taagaaaact aaaagataat ttgattaaga aatagatgtt cgtaaaagag
    40141 catctatttt ttatttttat cagatttaga taattttaat aataaaagaa ataaaaataa
    40201 gttcttaaat ttctaagaag aatttagaat atagtcgaaa taagaattgt atatttctga
    40261 aaattctaat tagtacaatt ttttccttta taaaattgaa aaaagatgta tttatttatc
    40321 aaaaatatta tattaaaatg atattaataa aaaaacattt acaatattag catatagtac
    40381 agaaaaaaga tgtaatttgt aaaatttatg ttaagcagta aaattaaaaa tttaaagata
    40441 ttatagggag gttataattt tatggaaaac gttattacag gtctaagtaa aggtgcagag
    40501 tggtttatcg gtttgtttca gaaaggggga gaacaattta taggtcttgt ttcaggtact
    40561 cttccaacgc taattgtatt aatggtagct attaactctt tgattaagat aattggtgag
    40621 gaaagagtta ataattgggc ttctaagcta ggaaagaact cttttacaag atatattcta
    40681 cttccattag tatcagtatt tttcttggga aatcctatgt gctatacatt tggtagattt
    40741 ttaaaagaag agcacaaagc aggattttat gatgcagcag tttcatttgt acatccaatt
    40801 acaggtcttt ttccacatgc aaatgcagga gaactttttg tatggttggg aatatcagca
    40861 ggtttgacta ctttaggtaa agaaactact acactggcat tgtggtattt tatagttggt
    40921 ctaattgtaa tttttataag aggtatagta acagaaaaaa tgtatgcttt tctaacaaga
    40981 aaaaatagag caacaaataa ggcttaggag gtagataaaa tggaggagaa taaaatatta
    41041 aaaatagaaa agggaacttc aggctgggga ggtcctttgt atataaaaaa agaagggaat
    41101 agaaataaga tactatcaat gactgctggt ggtatccatg aagtaacatt aaaaataaaa
    41161 gaactactgg gttgtgaaat tgtagatgga tttaaaactg gagtttctga tgaagaagta
    41221 gcagtagtta ttattgattg tggtggaact gctagatgtg gagtttatcc aaagaaaaaa
    41281 atacctacaa taaatgtaaa tccagttgga aaaacaggtc ctttagcaaa atttataaca
    41341 gaagaatatt atgtatcaga tgttaatcct aactgtataa gtgttgtaga tggggaagat
    41401 atgccacaaa aatctcaaga aaataaaagc gaaaataaga gttctattag aaagcctgat
    41461 aattatgatg aggttaagtc aaaagcacaa ggtgaatatg ctaaaaagaa cataatactt
    41521 tctattggtc aaggggcagg gcaagtagta tcaaaatttt atgatgcagg tcgagacact
    41581 atccaaatgg taatgaataa cgtaatacca tttatggcat ttgtaagtat gcttatggga
    41641 attattttag catctggact gggagactgg attgcaagag ttatatctcc acttgcaggt
    41701 aatattggtg gattattgat tatatcagta atttgcacac ttccattctt atcaccaata
    41761 ctaggacctg gtgcagttat agctcaagta gtagggactc ttgtaggtac acaaattggt
    41821 cttggtgcaa taccagcata tttagcactt ccagctttat ttgcaataaa tgggcaagct
    41881 ggatgtgatt ttgtaccagt aggattaagt ttgggagaag cagaaccaga aactgtagag
    41941 tatggtgttc cagctttatt ttactctcgt ttaataactg gtccaatagc tgttattatt
    42001 gcatatggag ttgcagtatt tgcattgaga taatatttaa tgtcaatata aggcttggaa
    42061 ttaattaata aaattgtaaa tataaattta agctagtcaa gattttttgt taatgaaaga
    42121 ctagctttta tactattaat tagctgtaat tatcgagtta gattaatact aaattttcct
    42181 ttattaaagt gaaattttat gtattaattt ggtttcaaat ttgtactaga atgaaatcaa
    42241 ggaggagata caaaatgagt gtaactgaga aaattccttc tattgaccgc aagatattta
    42301 agatattgat tatgtgtagt aaaaaagagt ttgtgagtat taattcaata gcaaatgaat
    42361 tgaatgtcac aactagaagt gtaaggacgt atataaaaca attgaataaa gatttaggta
    42421 atgatatagc agtaatcaaa tatataaagg gtcaaggcta taaactagaa ataaaagatg
    42481 agcagatact caataagatt attgatatga atagaaaaaa tgtattttca ttaaattcaa
    42541 aagaagatag agtagagttt atactaaatt acttgataga actagatgga tttattacac
    42601 ttgatagttt agctgatgag atgtgtgtag gaagaactac tttagtaaat gatttccagt
    42661 atgtagaaaa agttttggct tcatataatt taaacttgat taaaaaacag aatacaggta
    42721 tgaaattaaa tggaaatgaa cttgatatta gactgtttat attaaatcag ttgtataaaa
    42781 actcaaggaa agatttcagt aattcaaagt attttaaagg aatcaaaaaa gaagaaatca
    42841 taaatttaga agaaaaacta ttgactttat ttaaagaaaa taatttttat gttacagatg
    42901 aaatgttaag agaagttatt aactacatag tagttttagt ctatagagta aaagaagaaa
    42961 agaaagtaaa agactatgat gtaaagtttg atttacttaa atcatatgat gaatacttta
    43021 ttgctaggga aataaaacat ataatatcag gaatgtttga atgtacttta aatgatgaag
    43081 aaattattta tttaactata ccattagtta gtggaaatgc accagcatca gaatgtgctt
    43141 taaatagtag tagaattagt aaaaacattg atgagttgat ggaaaatata tttaatcaaa
    43201 tatatgtcga tatgggtatt tttataaatg aggatgaatt aagagtaggt ctaggatatc
    43261 atcttagttt tactttaaac aggctattat ttaatataaa gttaaaaaat gttttgttag
    43321 aagagattaa gcaaaattat atacttccat ttaaattagc acaaatagca ggaaaagtaa
    43381 tagagaaaaa gtataactta gaagtttcag aagatgagat tggatatata gcaatccatt
    43441 tcagtggata tttagaaaga aatagcagta gattctattc aataaaaaaa atagcaatta
    43501 tatgtagtac aggtctagga acagcaaaac tattgaaaat aagagtagaa aaactgatag
    43561 gaaataatcc taaaattgat actctttcaa gttttaattt gagaaatatt aacttagatg
    43621 aatacgatat agtttttaca actattgatt tagacacatc gaatataaat acaatagtat
    43681 taaaaataaa tacaatattt gatgaaaaca aattaagaga acaattaaaa acagtattgt
    43741 gcctaagaga agggaatatt gacactacta attctacaaa tttactaata aataatttgt
    43801 tagatgaaga taaatttatg atattaaatg aaaagactat acttgcttca ttagaaaaaa
    43861 tgatggacca tcttatggat ttgggatgta ttgatgataa gtttagaaaa aatatagtca
    43921 atagagaaga aaaatctccc acagtatttg ataaaggttt attatttcct cactctgtaa
    43981 atgaaaaatc agataagttt ttaatggcag ttggaatttt agaagaacca atagaatatg
    44041 caaatagaag tataaaaata attcttatga caatgtttcc atgtgagaat aagatagact
    44101 cagacttatt agtaaaaatt tatgaagaag ttttaaagat aggccaagat gtaaaattaa
    44161 cgaataagat aagtaaatgt agaacttttt tagaatttaa aaaggtgtta cttaaaaacc
    44221 ttatataact attgtacagc atttatagtt gttatacaga tttaaaaata atgtgatttt
    44281 tggaaggtgt ataaatatga aattattagt aattttattt gttgcttata ttttaaatac
    44341 tatatttata atgaagcaga ataaattgta ttttaaaact ttaaatagag ctaaaaaaaa
    44401 gggtgatata gtgtctacag gcaaaaagaa aagctatttt tctaaaggaa gtatagccat
    44461 tatatcttca gattcagatg ggtttataaa gtttggagaa attttaaaag ggcgtacagt
    44521 aatggctaaa tttaaagaga ttgaagaaat agaaggatta gatatatata gtgcagagca
    44581 aaaatttaaa gatgaagaga gtattgtaca agctataaaa tttataaaag aaaaaataaa
    44641 tgtttctttt aattaactca atataaatat aaattatcag gaggaatgtc atgaaatatg
    44701 aagttaagat aagtgggata ggcagtttag ttaaagagtt aatggatgaa agcaattgtc
    44761 ttattatata tgatgaaacc attaatgatg acgacttaaa ggatatatct gtaattcatt
    44821 cgatagcaac attaaaaagt gatgttgaaa taggagatac acttactata gggaatagag
    44881 attattgtat agtttcagtt ggtgatattg ctcagaagac tcttagagaa attgggcatt
    44941 gtacaatcaa atttgatgga aaatgtgaag taaatttacc aggagaaata catgtggaaa
    45001 taggaaatcc agatataact attggagatt taataactat ttcttaattt gaaaataaaa
    45061 ttattataac aggaggaatt ggtatgttag atttaaacag aaaacttgca aaattggaag
    45121 aggaaggtaa aaaaataaaa gtagctctta taggagctgg gcatatggga aatggaatgg
    45181 taagccaaat ggcaaatatg aaaggtattg aagcttctat tgttgtagat ataaatttgg
    45241 agttggctca taaagctttt actgatgcag gaatagatga agaaattata gataatgtaa
    45301 caaatgaaaa ggatgcagaa ataaaattac aagaaggaaa agtattgaca tgtaatgact
    45361 ttcttgtggc ttgtaaaact aagtcaatag atgtagttat agatgcaact gggggtattg
    45421 caattggtgc agagatagca ttaaactcta ttttaaataa aaaacatata gttatgttaa
    45481 atgctgaaac tgattgtgtt gttggaccaa tacttaaaaa attagcagat gatgctggag
    45541 tgatatttac aggttctgca ggagatgagc caggtgcagt aatggaatta tttgattttg
    45601 cagatgcaat ggggtttgaa gttagagtga taggtaaagg taaaaataat aaattagatt
    45661 tagattgtaa tcctgataca gttagagaag aagcagaaag aaaaggagct tcacctcata
    45721 tgatagcttc ttttaaagaa ggaactaaaa caatggtaga aatggcttta atgtgtaatg
    45781 caactggatt tgtgcctgat gtaagaggtg gtcatggtat tgaagctaca gttaatgaag
    45841 tacctaagaa atatgcatta aaaagcgaag gtggagtatt agataattat ggtgtagttg
    45901 attttgtaaa tggtatagca cctggagttt tcgtagtagt agcccataaa ttaaaagcag
    45961 ttaatgatga actaaaatat ttaagtatgg gtgatggacc taattacata ttatatagac
    46021 catatcattt atgtagttta gagactcctt tatcagcagc tatggcagtc ttagaccata
    46081 aggctacaat agtacctaaa gctggactag tagcagaagt tatgactata gctaagaaag
    46141 atttgaaaaa aggtgagttt atggatggtt atggagcata tacatgctat ggtactatag
    46201 aaaaatacga tgtagcaaag gctatgaatg ctgtacctat tggtttgata agtaaaaaga
    46261 ctaaagttgt aaaagatatt aaaaaaggtg aagttataac ttacgatatg gtagagatag
    46321 aaaaagatac tactttatat catttaagac aattgcaaga aaaaatattt gggtaagatt
    46381 tgatggtaat ataaatagat attagtaaaa agggttgatg gttattttta aatcaaccct
    46441 tttaaatttt tatatattct tgttaggata ctttctttaa aagtatatta taggttattt
    46501 gtagtcgtaa aaattatttt gaattagttc tgcaatttta tattcacatt gaaacaatat
    46561 tattaaaaat tttaatataa aatgaattaa aatgaccaat tatgtattat aatattaact
    46621 gtaatactaa tatagttcta ttaattaaag aaatatcccc cattaatata taataaatat
    46681 ctttaagcga gagaacttag taaaaaatat atcgtattca ataaaaaatc tgtttacaga
    46741 atggtatata tagttatata atatactata taagatgcga aaagataaaa agtatagcac
    46801 aatgaaagaa ggtgattatt attcagctta atgaaagaca actaaaaatt atagatatag
    46861 ttaaggaaaa tgaaccaata acgagtgaaa gtattgcctc cagcttgaat gtgactcgtg
    46921 ctacacttag atctgattta gctatattaa caatgacagg aatattagac gcaagaccaa
    46981 aagttggata tttttattca ggagttagtg aaataaattt aattggtaaa agtgtaaaag
    47041 aaaaaacagt agaggatata atgagcatgc ctgtactagc taagaaggat gaaagtatat
    47101 atgatgtaat agtcactatg tttttatctg atgtagggag tatagttatt atagatgaga
    47161 atgaagagtt atgtggagtt gtttccagaa aagacttgct aaaagcaact ataggaggtt
    47221 ctgatataaa taaaatgcca ataggtatga taatgacaag aactccaaat gtagtcactt
    47281 taactaaagg agcaagtgtt ttattagctt caagaaaaat aatagaacat gaagtagatt
    47341 cgattccgat tgttgaatat aagggagaag acaaaaatca tatgagagtt gttgggagaa
    47401 tatcaaaaac caacataact aagctattct tagaaatagt tgacaattaa ggaggtatgc
    47461 tggtgaaaaa cctaattata tatgcagtat cagattcagt aggggagact gcacaacaag
    47521 ttgcaaaggc atgtatgtct cagttttatg tgaatgaaac ttatgaaata aaaagatttc
    47581 catacatgat taataaagga gtactacttg aaactttgga gaatgcaaaa gctgaaaacg
    47641 ctttaattgt atatacatta gttgatgaag aattatgcag tattgttgaa agatattgcg
    47701 aaagagaagg tcttagttgt atagatttaa tgacagatat actaagagaa ataagcaaga
    47761 gaacaggaag aaaacctaaa agagaagctg gtataattag aaaattagat gaatcttact
    47821 ttaagagagt tgaagctata gaatttgcag tgaaatatga tgatggaaaa gaccctagag
    47881 gtgttcttca agcagacata attttagtgg gaatatcaag aacatctaaa actcctttga
    47941 gtatgtattt agctaataaa aatataaaag tagctaatgt tccattagtt ccagaaatac
    48001 caattcctaa agaagtgttt gagatagata ctaaaaagat aataggtctt actaattcac
    48061 ctgaaaagct gaatgagata agaacccaaa gattaaaagc tttaggattg tccagtaaag
    48121 caaactacgc taatttagaa agaatacttc aggagttaga ttattcagaa gagataatga
    48181 aaagaattgg atgcccagta ataaacgttt caaataaggc aatagaagaa acagcaggta
    48241 taattttaga cataatgaaa gaaaatggtc taaagatata caaagaaata gaaatttaat
    48301 aatgtctatt aataaaaatg atataaatta aaataaaaag attaatgggg gatttaacaa
    48361 tggaaactaa gtatgtttat agttttggtg aaggaagcaa agacatgaaa tctttactag
    48421 gaggtaaagg tgccaattta gcagaaatga ctaagatagg cttacctgtc cctcctggat
    48481 tcactataac aacagaagca tgtaatgatt attatgttaa caatgaaagt ataagagcag
    48541 agataataaa agaaatagaa gagcatttag ctactttaga aaaagactta aataaaacat
    48601 taggatgcaa taagaatcca ttattagtat cagttcgttc tggtgcagta ttctctatgc
    48661 caggaatgat ggatacaatt cttaacctag gtcttaatga caatagtgtt gttggcttag
    48721 cagaggctac acaaaatgaa agatttgcat atgatagtta cagaagattc atacaaatgt
    48781 tttctgatgt tgctatggaa gttccaaaat ataaatttga aaatgtatta gacagagtaa
    48841 aagaagcaaa gggatacaca gttgatacag aacttacaac tgatgattta aaagaaatag
    48901 taaaagaatt taaagcaatt tataaaaaag aaataaaaaa tgatttccca caagacccaa
    48961 aagagcaatt aatgcttgca atagaggctg tatttagatc atggaataat cctcgtgcaa
    49021 tcgtataccg taaattgaat gatatagctc ataacttagg aacagcagta aatattcaat
    49081 caatggtatt tggtaatatg ggagaaacta gtggtacagg tgttgcattt actagaaatc
    49141 cagctacagg agaaaataaa ttatttggtg aatttttaat gaatgcacaa ggtgaagacg
    49201 ttgttgcagg tataagaact cctcaaaata tatcaactct tgcagatgta atgccagctg
    49261 tattcgatga atttgtaaaa attactcata tacttgaagg tcattataaa gatatgcaag
    49321 atatagagtt tactatagaa aatgaaagat tatatatact acaaactaga aatggtaaga
    49381 gaacagcagc agcagcaata aatgtagcgg ttgatttagt tgaagctgga ataattgatg
    49441 aaaaagaagc tatcatgaga attgagccta atcaattaga ccaattatta catccaaaat
    49501 ttgaagataa ggcattaaaa gaagccaagg ttatagcaaa aggtttacca gcatcaccag
    49561 gtgcagcaag tggtaaagtt tatttcaatg ctgatgatgt agtaaaagca aatgaaaaag
    49621 gagaaaaagt agttttagtt agattagaga catctccaga agatatagaa ggaatggtta
    49681 aagcagaagg aatccttaca gctagaggtg gaatgacatc acatgcagca gttgttgcta
    49741 gaggtatggg taaatgttgt gttgctggat gtggagaaat aaaagttgat gagtttaata
    49801 aagaaataag agcacttgat gatgtagtta taaaagaagg tgaatacatt tctatagatg
    49861 gttctacagg aaatgtgtac ctaggagatg ttaagaaaac agaagtatct ttaactggaa
    49921 actttgaaaa attaatgaac tgggtagaca aacacaaatg tatgatggtt agaactaatg
    49981 cagataatcc tagagatgct cgtgcagcta tagagtttgg tgcagaaggt ataggtctat
    50041 gtagaactga gcatatgttc tttgatgaag ctagattgcc agcagttaga gaaatgatat
    50101 tatctaatac agtagaacaa agagaaaaag ctcttgaaaa aatattacca atgcaaagag
    50161 aagattttgt agagttattt aaagttatgg atggaaaacc agttaatata agattactag
    50221 acccaccact acatgaattt ttgcctcatg atgatgagac tatagaagaa ctttcaaaat
    50281 ctatgggaat aaaagtaagt gatattaaga agagaatagt tgatttagat gagtttaacc
    50341 caatgcttgg acacagaggt tgtagacttg caataactta tcctgaaata tgtgtaatgc
    50401 aatctaaagc tataatacaa ggtgctatag aagcaatcaa agcaggtgtt aaagtttctc
    50461 cagagataat ggttccatta gttggagaag taaatgagtt aaaaataata agaaaaatga
    50521 tagtagaaac tgttgacgct ataataaaag aagaaggtat agaagttcct tatactgtag
    50581 gtactatgat agaaatacct agagcttgtt taactgctga tgaaatagca caagaagcag
    50641 acttcttcag ttttggtact aatgacttaa ctcaaatggc atttggatat tcaagagatg
    50701 atgctggtaa attcttaggt caatatgtag atgaagaaat attagaaaaa gacccattcc
    50761 aagtactaga ccaaaatggt gttggtaagt tagttaagat gggagctaaa ttaggtagag
    50821 aagttaaacc agaattaaaa ctaggaatat gtggagagca tggaggagaa ccatcttcag
    50881 tagagttctg ttatagtgta ggacttaact atgtatcttg ttcaccattt agagtgccaa
    50941 ttgctagact tgcagcagct caagcatcta taaaaaatcc tagataataa tagactgcaa
    51001 aatatgtaac taaataaaaa taaaatcccc tattgttcaa tgtatcaaat taagtatttg
    51061 taaattgaat ataggggatt tttattataa aaatttaact tatacagttg taagtgaaac
    51121 gtatttaatt atattgcata tattattgta gagagaaatt tcaactatca attaaattga
    51181 gtttactgga ggggataaag ttgacaaagt gtcctaaatg tggaaaggaa gtatcatcac
    51241 gtccaggtag tatatgccca cgatgtggat ttaaagtagc agatgagagt ctaaaaataa
    51301 gatgtccaga acctagttgt agggctttgg tatctaggaa actggattat tgtcctaaat
    51361 gtggatgcaa acttagagga tataatattt ctgaatttgt taacatggta agatgtaaaa
    51421 tagatgagac atttgataaa aaataattaa atttagagtt aagcttttga gggtgtctca
    51481 aaatgaactt tttagttcag aaggcactct ttttgtatgg aatcaaatat atttttataa
    51541 tttaaacaat aaaaaagagg cttatctcta ttttagtata atccccttat agtagacatt
    51601 taaataaaag gctattataa taagtctaaa aagcgtatac tctaaggggg tttttctatg
    51661 tctaaaaaac ataaaaaata tagcaaagaa cttaaactaa aagctgtaaa tttatatata
    51721 aaagaaggat actcatcata caaaattgct gagatgctga atataagaag c
//
LOCUS       DAMJYN010000018        51769 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.018, whole genome shotgun sequence.
ACCESSION   DAMJYN010000018 DAMJYN010000000
VERSION     DAMJYN010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 51769)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51769)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51769
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.018"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            145..495
                     /locus_tag="PC466_001187"
     CDS             145..495
                     /locus_tag="PC466_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HDF2768581.1"
                     /translation="MSAKVTNQYGNIEIDNQVIAQVVYRAAMESYGLVGLAYKSKGIV
                     ELLKGENATKGVRVEEVEEDAIAIELYVIIQYGTNISTVANNIIDRVKYVVEKMTGVR
                     VTRIDINVQGIRVK"
     gene            514..2157
                     /locus_tag="PC466_001188"
     CDS             514..2157
                     /locus_tag="PC466_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HDF2768582.1"
                     /translation="MIQYIDGKRLREMFISGANNLQNNKELVDKLNVFPVPDGDTGTN
                     MSLTISYALKELAKVENDNISDIGKALSKGSLMGARGNSGVILSQIIRGIAKSIEGKS
                     KLSTEDLAKAFKNGSDTAYKAVIKPIEGTILTVVRESGEFAIKTAKKEKDVVKFLSML
                     VKESNSSLERTPDLLKNLKEAGVVDSGGKGLVLIYEGMLASIKGDNIEIKNVDLDTNI
                     STSMDFAKSTTSTDDIKYCYCTEFILESSKVEDTKIRDIMMAYGDSLAVVGDDGVIKV
                     HVHTNDPGNVLQEALKYGQLLTIKIENMKLQHENTLLDVEEKKENDSEPLEEEKEFGF
                     IATSMGEGLANIFKDFGVDHIIEGGQTMNPSTEDFMNAIKHINAKNIFIFPNNSNIIM
                     AANQAKELSDKNIIVIPTKNTPQGFAALVTFNGELSEDENKEAMMNALNSVKSGQVTF
                     AVRDTVMNEIDVKEGNIIGIAEGNLLSAGDYVDEVTSNLIEKLVDEDTAIITLFFGED
                     VTESQANELRTSLEEKFEDVDVELYYGGQPLYYYLISVE"
     gene            2238..4295
                     /gene="recG"
                     /locus_tag="PC466_001189"
     CDS             2238..4295
                     /gene="recG"
                     /locus_tag="PC466_001189"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HDF2768583.1"
                     /translation="MDLYKDVQYVKGIGPKKADKLNKLGIFTLKDLLYYFPRQFEDRN
                     NLKKIAQLEDGEKVTIKAVISSINTFSPKEGMTLTKIDVKDETGSAKLVFFNKSYIKN
                     TFRPGDSILVFGKVKKKFNNLELTSCELEYLTNSPKNTCRFMPVYQLTYGVTNKEIMS
                     IIRTVLEDKELIIQEYMPQRIIEKYRLCSIDFAVRNIHSPSSKESLKIALYRIVFEEL
                     LILQLGLFVFKSGRNKEDGIKFETSKDLKKIISALPFKLTKAQNRALDEIIQDMNLEK
                     IMNRLVQGDVGSGKTVVALLALANCVLNGYQGALMAPTEILAGQHYISLTESLKDFGI
                     NVGLLIGSLTKKQKDTVLEQIRNNEIDILIGTHALIEDKVEFNNIGLVITDEQHRFGV
                     MQRSKLSLKGANPDILVMTATPIPRTLALILYGDLDISIIDELPPGRQPIETIAIEKS
                     KRDRAYNNLVRREVESGRQVYIVCPLVEESEAIEAKSAVELVEELRAEYFHDLRLGLL
                     HGKMKSSEKDEVMERFKNKEIDILVSTTVIEVGVNVPNATLMIIENAERFGLAQLHQL
                     RGRVGRGSHKSYCVLIYDSKTDVCRQRMAIMEETNDGFKISEKDLEIRGPGEFFGTRQ
                     HGLPELKVANLFKHIKILKLAQQEARYILGEDNNLQLKENMALKKEIIDKFKDTLKEI
                     SLN"
     gene            4354..4908
                     /gene="rsmD"
                     /locus_tag="PC466_001190"
     CDS             4354..4908
                     /gene="rsmD"
                     /locus_tag="PC466_001190"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HDF2768584.1"
                     /translation="MRVISGKARGLKLNTPKNEDVRPTTDRVKESLFNMINSYIMESE
                     VLDLFAGTGSLGIECLSRGAKSCTFVDISKESIDIVKSNVKKARVESESIILNLDFKT
                     AIDKLKLQNSKFDIIFMDPPYYKNMFIEAIEKIDNSNLLNEDGIIVVEHDTNDLFPDK
                     ICKLEKTRDKKYGNTTLTFYKMEA"
     gene            4910..5407
                     /gene="coaD"
                     /locus_tag="PC466_001191"
     CDS             4910..5407
                     /gene="coaD"
                     /locus_tag="PC466_001191"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HDF2768585.1"
                     /translation="MENKPRKAIFAGSFDPITNGHLDIICRASKLFDELQIGVLNNPN
                     KKGLFSFDERVKLIEKSTSHLNNIKVVTFDGLLINYCQENGIGALVRGVRSGADVDYE
                     LQMAHMNRELNPDIETIILPSCTKYSFISSSLIKEVLLFDADIKNLVPKIVLEELKKK
                     TSGGN"
     gene            5411..5935
                     /locus_tag="PC466_001192"
     CDS             5411..5935
                     /locus_tag="PC466_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768586.1"
                     /translation="MKIDLEMIELFEQLEEIFRSASTIPFSHKCTVDKDEVLAIINDI
                     RTLIPEEVTQAVWINKERNKIISQAKQDATNIVEQAKKEAERIQQEYQDNIEELKKNS
                     EDVVKAYVESSEPVVQADQRAKDIVDRAERIANEIRIGSIEYAEDVLSSVEYNLREIL
                     EEVKRDKAELRPKK"
     gene            6279..8198
                     /locus_tag="PC466_001193"
     CDS             6279..8198
                     /locus_tag="PC466_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDF2768587.1"
                     /translation="MKERAKKILDFIIKNNNVTSQELQERFNVSKRTIYYDILAINEQ
                     LGKSGNIKNVKHKFIFEGNLCDARKIISTEEDKFLDSDYRKTFILNKILLGEKISIEK
                     LTNEMLLSKNTVVQTITDVKKYLQTMGLRLEYKGKYKIIGDEYVIRELFLIIVQENVL
                     EINSISKEVSSFDTKGHIKLTDYSLLNLTKFVEFLNKRIRDGKTLYSYKYLNEAKKIS
                     YFSNCKELLCEEANENEQAYICTYISSLPSLNSEVKEDVVEEYVDKLIDKFEVNTAIK
                     LESKHEFKKNILRHLHSSYNRIRFKFPIRNPMLDETKYKHESLYKIIKSIIENEEEFP
                     VFEGIREEEIGFIAAYFGGYLRGSRDNGLRRNKVLLVCPNGLMVSKSLEIQLYKYIPT
                     IEIVGIVSIKQLKEVNVYYDYIITTIDIQNVNNVIVVNPLLTSSDVQLLMNKLISVKE
                     NEKYFNLELIIQAIRKNGVINNEEALKADLLNIIHKIDEGEMYQPMLKELINAERVNI
                     IKSVRDWKEAIKIASKPLLEDNSIEELYIENMIKSVEKYGPYIVLADRFALPHASSKE
                     GVNKLAMSLLIVEDEVDLLGKPVNIFMVLAAVDNTTHIRALASLSEMMYEEENVKLII
                     NGDKSSILELINKQN"
     gene            8211..8498
                     /locus_tag="PC466_001194"
     CDS             8211..8498
                     /locus_tag="PC466_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2768588.1"
                     /translation="MKILAVCGFGVGSSMVLKMTIQKALKQLGIECEVENTDINSARG
                     ADCDCIFTSQELLNELKGTCNVDVYPVKKYMDLAEVTEVVQTFLSDKNDKK"
     gene            8631..9890
                     /locus_tag="PC466_001195"
     CDS             8631..9890
                     /locus_tag="PC466_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HDF2768589.1"
                     /translation="MLDFISNNILRNPSMLIGLIAAFGLVLQKKKASDVIKGSLLAAF
                     GIIIMETGTGMLVSSIAPINGAFQSISGGAVTKGLSDVTFTASYGGIIGLAMFAGLAI
                     HLMIARFTPIKTIFLTGHMLYWFPFIFVASGVEAGLNGGVLIAFAAVLSALYWSIMPW
                     LLRKYVFDVIGDDSFTLGHPSGCLALISGFVAKLVGNKEKSTEDINIPQSLSFFREIS
                     ISGGMAVFLMFIVVGIVIPGAFKDSNEFIGTYAIKQGLSFGAGLIIMLHGVRMLINQI
                     MPAFQGISEKVVPNALPAFDCPILFNYKPNAVLIGFLVAMLTSTAMILICNYFNVFNL
                     LLIPLVITSFFECGAAAVIGESQGGIRGAIIGTAIAAIFMVVLVGISAVIYSGTIQNW
                     ILIFGGNDLSLFGIISKFIGSLFGGIL"
     gene            9893..10633
                     /locus_tag="PC466_001196"
     CDS             9893..10633
                     /locus_tag="PC466_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HDF2768590.1"
                     /translation="MKFKYIDEIRRLIDIIENEEKVNMEKAVQILVEAIESKNAIFSF
                     GASHAGILTEELFYRAGGCVLINPVFAKSLMLDTAPITHTSKMERLEGYGTALADKTP
                     IKKGDVVIVHSVSGRNPVSIEFAMKAKENKAIVICITNLSYSKSVSSRHSSGKKLYEV
                     CDLVIDNHGQKGDACVEIDGLNQKVSPTSTVIATTVMNSIIAQATQELVNKGLKNPPI
                     FYSANIDGGDELNKKIFDEYKSVIHYEY"
     gene            10956..12266
                     /locus_tag="PC466_001197"
     CDS             10956..12266
                     /locus_tag="PC466_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HDF2768591.1"
                     /translation="MKKENKMEGIKVGMLKKLCSLAMVAIMTTTLITGCSSGNGKDSK
                     KDGEKEKLVLWMPPVENNMKEVWDPILDKFEEKNNCEVDLQIIPWDNYSEKFATAISA
                     GEGPDVGYMYAEMYPQFIESGAVEDLTNYATKEDKEQSIYIKTSEMMGGMYGMPFQAA
                     NPGVLYYNKDILEKLGEKPPKTWEDFKRICKKATQDTDGDGKIDQWGLAQGWGAKTFG
                     NLNWNWYPYLWQAGGDIFNDDLKSVKFNDKSGLEAANFLKELQAYVPEDSLSKDSNEM
                     IESVFGPGKAAFTIMLSSAATSVFDESFPDLNWGFVTGLEDKKAATFGAVDHLSLMSS
                     AKNKELAYKLIQHMLSVESMTEFHKAIPRAPITKGEPYQGDERFKEMVENDKNVYRPL
                     VVGPHGVEIYEYLWKELQTMISGDKTPKQALDDAAKYSNDLLAQ"
     gene            12364..13281
                     /locus_tag="PC466_001198"
     CDS             12364..13281
                     /locus_tag="PC466_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDF2768592.1"
                     /translation="MENLVREFEENSKRKKTKLNIKPYMYILPLGIILVAFYVIPIIM
                     SIYFSFTKYNIISPATFIGLENYKKLFTDETLKVSIINTIKFTVVVVPCQTILSLILA
                     VWITGKGNSKIASFAKGAIFIPVLSSMVLIGMVWRALLNGEGSIIYQVLGAFGIESSK
                     LLGDSKTALPTLMFISMWKNIGYFMVIYISAIMNLPKHCYEVAKVDGATKLQEFIKIT
                     VPLLKPTTIMVVFLGSIWSLQVFDLIYTVTGGGPGISTMSIVMHAFNLNFKNFNSGYA
                     MTVANVLFLLIAVVSILQNKLVKRDNSDF"
     gene            13297..14106
                     /locus_tag="PC466_001199"
     CDS             13297..14106
                     /locus_tag="PC466_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HDF2768593.1"
                     /translation="MKTARRLLSDGLLLFIACASLVPFIYMLIISLKITYNSYSLDIS
                     FSTVTLQNYIDIFTKKGFAQYFFNTAIVSFSGVLLNLVFSTLAGYSFAKMDFKGSDKL
                     FLFMIMTLIIPSQVTMIPLYIIMKHLGWINSYLALIMPIPTAFGVFIMRQAILGVPKE
                     LLESAKIDGCSDFRILIQIVLPLIKPALITLAIFTFMGAWNEFMWPLIATTKDAMRTL
                     TVGLSTLKTFQITNYGQMMAGATITFLPPFIFYLILQSKFVEGVSLSGIKG"
     gene            14163..15911
                     /locus_tag="PC466_001200"
     CDS             14163..15911
                     /locus_tag="PC466_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4091 domain-containing protein"
                     /protein_id="HDF2768594.1"
                     /translation="MEISYVLKDCTFKHNKYSVIEAETWKEKDLDIVVAKGEKFAFQI
                     MLKATEEFNCTIDKSSTISWKGLENRVRLALNVPNSLENNFSINILGYVQDDTKAFVN
                     DAILRDKDVLVEQYLPQTFWIEGQVPEDFEENNLNIGIDIFKSFGYEDEEKVCTIDVP
                     VKVRNVVLKPLDKSKFFLDLWQHPSCLARMYKVELWSDIHFEIVDNYLKELASLGEKV
                     ATVIVSDYPWAGQSCYKVYKNPSNLYEYNMVSVSKGLDGKIKCNFESMDRYISIADKY
                     KMSKEIDLFGLLGNWCAGEFGNPVEGYKDPIRVRYFDENDKVFKFINNTNDLKEYIGL
                     VLNHLIECGLWDRVRIIADEPNNPEVVKECIEFINSTVGTHQVKYKSATHDQNFLDRA
                     KDEIDDMSINLKLTIQNYKDIENLKKKINDKGGILTWFVCCFPEKPNSFLSSPFVENR
                     IIGWYTYYFGLDGFLRWDYNLWTEDPWKDSSYKFPIWKAGDMFFVYPGKDLKPVRSVR
                     MENLRFGIQDFELFTMLEKEKGREYIEVELMQELLNKKENAEIKGFGDIELGYSLDNW
                     GYDKVKKYVLELLDRV"
     gene            16174..17196
                     /locus_tag="PC466_001201"
     CDS             16174..17196
                     /locus_tag="PC466_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 5 protein"
                     /protein_id="HDF2768595.1"
                     /translation="MFGGINIKRIGIIIMFFLSIAFIGFYLAIRGNSDTVKMQRGINI
                     GNALESPKDFPWDVKMSNKFFDDIKDAGFDTVRIPVRFSDYTSDSDNFKIDEEFFKKI
                     DKYVDYALDKDLIVVLDLHHFEEIMKEPRVHKEEFLKIWQQIANRYQKYDKKLVFELL
                     NEPKENLSSQLLNEYIEEAIKIIRKTNPKRTIIVGPYNFYQIDYLNELNVPKDSNIVV
                     SFHYYEPNDFAFQGNIYHNGFEHLSNITWEGTNEQMDYLKKRFDIVENWANKNKVKIF
                     LGEFGVTKEAPEASRRAWIKAVREEAEKRNFSWAYWELASGFGIYNQIEGTWDRDILS
                     ALIEKR"
     gene            17201..19507
                     /locus_tag="PC466_001202"
     CDS             17201..19507
                     /locus_tag="PC466_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDF2768596.1"
                     /translation="MKKNSKKILITLTIITNIVYILWRIFYTVPKEEGMFALICAIIL
                     LFVEIMGMMEMFVHYYGMSNIEYPEKPVISEELYPHVDVFIATYNESVDLVRKTVNGC
                     IHMQYPDKKKVHIYICDDGNREEMRILAEKMGVNYITRTEREGAKAGNLNNAMQHTNS
                     PLIATFDADMIPMHDFLIATVPYFLKNEQAKKDGEKEEYEKVGFVQTPQSFYNPDLFQ
                     FNLHSEGRIPNEQDYFYRDIQLARNRTNSVIYGGSNTVISREALEEVDGFYTYSITED
                     FATGILIQSKGYRCYAIPEVHASGLSPTDLKSLIKQRERWARGCIQTGRRLNILFRRG
                     LGFWQKISYISSITYWYASIKRFVYIMAPILFSVFNVIVVKCTLLQVLVFWLPMYILS
                     SLSLKIFSQNIRNTRWTNIYETIMFQSLMPAVILETFAISKNKFSVTNKNKLEENRMY
                     KFLQGIPYFIYMVLSIIGILKMFVAIFKMSSMTYSVVLFWLIGNLFNLVMATLFISGR
                     QQLRKSERYIAEIDFKLKQNSYVLSSKTIDISENGFAFLLENPEYISPEEEFEVEFRE
                     KSGNEMYIANMKAKIVNVVEVNSKWKYAAYITHIEDSEIDNWMCIVHDRIPTLPMTIS
                     NQLGFFDDLQINVKKRIEKIRTLSRRSPRINMNFQMDIKNTGKLRIVNFNYQYVLLNF
                     ENKNIYPKEIALEINENIVLECDLCEGKIDERGLLYKVNNIDSIMQNFFLRDEMMDWI
                     LQNKTIPVSNPSEKKEKSIDEFEPMEYI"
     gene            19479..20594
                     /locus_tag="PC466_001203"
     CDS             19479..20594
                     /locus_tag="PC466_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768597.1"
                     /translation="MSLNPWNIFRRDEMKTLKVFFCSAKYLILVFIFFINTTFISSAT
                     SDKILDLSFKKIETDLSSRITYEDTGVKIETDSSKSDKERYLYIYQNIKENWSMYNNF
                     YIEIQNKNKSSQKINLSIQSKNMLEFRLKEGSEIFLEDKNIIYSDKIKEGCIEVPGEF
                     EGKIYVNFNSLINEKSNVVLDSSMLSNIVSWGITFIPSDEEHNIVIIKKISLLSEEKL
                     SFLHNIKITGNEEVQIPVLGQSISQYEVLGLKRDSKIKYSLMGKQDNVSISQNGKLTL
                     SNKAEPGQIILQVNVDDKFKIGRKIALTESWSINKKDKDGVPYTLVSPEQSPTVQYMK
                     KINFMNNIITFVRILFVSLVIICFGIYLYWKKCSKTK"
     gene            20612..22030
                     /locus_tag="PC466_001204"
     CDS             20612..22030
                     /locus_tag="PC466_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBOAT family protein"
                     /protein_id="HDF2768598.1"
                     /translation="MLFSSLIFLFYFLPITLVLYYVFRFNRTIQNMILLAVSLFFYAW
                     GEPKFVVIMIVSIIMNYIFGLLVDRYRESKIKVKVFLVLMCVYNIGVLFIFKYLAFAL
                     RNISELINTELTIPSIVLPIGISFFTFQGMSYVIDVYRRHGEVQKNPFYVGLYIAFFP
                     QLIAGPIVRYESVAEQILNRKETWNKFSIGTCRFITGLGKKVLISNNMAIVADYIYTM
                     NSQGEIAASLAWLGSIAYTMQIFFDFSAYSDMAIGLGLMFGFKFEENFNYPYISKSIS
                     EFWRRWHISLGMWFKSYIYFPLGGSRVANKDIMIRNMFIVWLFTGIWHGAEWTFVIWG
                     ILNFVFLIIERFIMFEKIENHNFIKHIYALLVVNFGWVLFRSPNLKEAYNYFKAMLGG
                     NGVIWSDYTYMFLKEYWVFFIFAFIFSVPIAKKINKFVVEQAKYSMIFNVFYPISAIL
                     LFFISVTYLVTGSYNPFIYFNF"
     gene            22045..23253
                     /locus_tag="PC466_001205"
     CDS             22045..23253
                     /locus_tag="PC466_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768599.1"
                     /translation="MNRFFKVRLITAIMFLIILFAFSIFNICYSGKDMIQEIKNSVAE
                     KSSLKDTISSIDNTVNDKVIYKNTFIETYGYLQKLMGKNEFSKFSVVKDTSGKMHYTY
                     FAKAPNPVGVIADRVRKFSEEMEKQNTKLVYLMTPDKYIKGVTKFPKGIPYSYSNETA
                     DNFLNQLKKYNVDYIDFRENILKSGIPKDDLFFKTDHHWKVETSFWAFGELVEQLNKK
                     YNMNLDENHYYRDKENYNSIVYPKSFLGSMGRKTGILYGGIDDFTLIYPKFKTNYTYY
                     TDSKSQKFELKGRFEESLILSYPFNADLDLMDGQSDKYFTYLLGNRPLVKIKNIENPD
                     GLKVLFVKDSLIVPTAAFFSSVCSSIDMIDPRYYDGDILEYAKSHDYDFVFISVYPQN
                     LTKEFFPFCK"
     gene            complement(23334..24722)
                     /locus_tag="PC466_001206"
     CDS             complement(23334..24722)
                     /locus_tag="PC466_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:dicarboxylase symporter family
                     transporter"
                     /protein_id="HDF2768600.1"
                     /translation="MESSFLSQFLMITDFKTIFFIILLLGTFFIVRQFEKKKIKFSLR
                     TIYATVLGLILGIIIQAFAGFPNDTTQVTWLQEVSKWYSLFGSGFMDLLKMLVVPLVF
                     LSIIKVIINMKDNNLGTLTFKSLGMLLATTAIAAIVGIIVANIMKLGVGANMPTLVEN
                     QELKEINSLVDTLRGLLPSNPVMAMANGNIVATIIFATFIATSIKRLSKKHFETIKPF
                     IDFIEASYKIIVSVSMTVIKFMPYAVVALLANTITSQGISSIVSVLQFILALYISVAI
                     LFTIHLIFITLNGLNPITYIRNSTEALLLAFTSRSSLGTLPVTIESLVQNHGVDEGVS
                     SFTASLGANMGMNGCAGIYPALMAVTLANMAGVNMDMSLYVMLLIVITISSFGIAGLP
                     GTATMAVSVVISGVGLGSYFPLVGGILAIDPILDMGRTMINVNGAMVSSITVGKSLGK
                     IDKEVFGKKNIS"
     gene            25064..26398
                     /locus_tag="PC466_001207"
     CDS             25064..26398
                     /locus_tag="PC466_001207"
                     /EC_number="1.8.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-disulfide reductase"
                     /protein_id="HDF2768601.1"
                     /translation="MRVVIIGGVAAGMSAAAKLKRIKPEYEVVVYEKTEIVSFGACGL
                     PYFVGGFFDDADELLARTPEKLREAGIDLNIFREVVEVDSESKKIKVKNIKTDEIYED
                     YYDKLMIATGARSIMPPIKNIKLKNVSTLKSLYDGEYLKKLLSNEDNKRVTIIGAGFI
                     GLEAVEACKKLGKDVDVIQLEDRILPQVFDKEMTDVLEEEINRHNVNLHLDEMVVELC
                     GEDKVEKVITNKGEIDTDVVIIATGVRPNTEFLSNTNIKMLKNGAIVVDEYGRTSVED
                     IYSAGDCATIKNIVSNENVYVPLATGANKLGRIVGENLAGREVSYQGSLSSSCIKIMD
                     MEAASTGITEKQAKDLGINVKSKFISDYNQTHYYPGRNKIYVKLIYDADTKVILGGQV
                     AGFKDAVQRANVLAAAIFGKMTTSQLGMLDLCYAPPFARTWDVLNVAGNVSK"
     gene            complement(26527..27444)
                     /locus_tag="PC466_001208"
     CDS             complement(26527..27444)
                     /locus_tag="PC466_001208"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011969064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HDF2768602.1"
                     /translation="MIDLTLLGCGGNVPMPNRFLSSVFINYKGRKILIDCGEGTQVSM
                     KLKKCGFKDIDLICITHLHGDHIFGLLGLLSTIGNSGRTSDLTIVGPVGIVDCIRSMR
                     NLVEYVPYTLKIIENPQGNFSLDNKVLRNLEISTISLEHSIECLGYSFNFRRNPKFDI
                     DKATKNEVPKILWNKLQEGQNIVLNSKQYTPDMVLGELRKGVKISLTTDTRPIESIPD
                     FIKDSDLFICEAMYGDDLDISKAVRNKHMTFREAANLAKLGNVKQLLLTHFSPSLDIP
                     SMYLENATNVFENTILGEDRLSLRLNFDE"
     gene            27652..28536
                     /locus_tag="PC466_001209"
     CDS             27652..28536
                     /locus_tag="PC466_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4846 domain-containing protein"
                     /protein_id="HDF2768603.1"
                     /translation="MKVLKKITILSLITLTLVGCSNGEDKKVVEGSKKIQNSKKDEQP
                     IIVHKDANILKDRYEPPKGFKRVDVEKGSFESFLRNTKLKNYGEKVKYYDGRIKESKG
                     IYDSVFDVDIGNRDLHQCADAIMLMRAEYLYQNKLYDEISFDFVDGFKAKYSKWAQGY
                     RISVKDSGSSWYKATEYSTSYESFRKFMDIVFAYSGTLSLEKELEPVKVEDMKIGDVF
                     IVGGSPGHASIIMDMAENEKTGKKVFMIAQSYMPAQQTQLLINRKNPNLSPWYSLDFE
                     GDLTIPQWTFKRDQLKRF"
     gene            28749..30590
                     /locus_tag="PC466_001210"
     CDS             28749..30590
                     /locus_tag="PC466_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HDF2768604.1"
                     /translation="MKIRRYLILVIIILITTSQSFISYGLERFEEITIFHTNDIHGRY
                     AEGDDHIQIGNLATLKKETPNSILVDAGDCLHGLPIVNMDRGKSAIELIKCAGYDYIT
                     PGNHDFNYGKDRLFELSKSANLGENTLKFLSSNIFENGKKVFDSNDIKEIDGIKIGFF
                     GLSTQETKNKTGFKNVEGLEFKNPIESATEQVNELKGKGANVIVAICHIGTNSLSKPN
                     SIDIANEVQGIDLIIDGHSHTKFENGKQVGDTLIVSAGQYLENIGEIKLTLDTNDVEN
                     IKIENKSVRLIGKEEALKYKLDYVVSKKVDEIKEQQEKILDKVIGATTNTLDGSYENV
                     RTKETNLGNLISDILLDKTKADISLFNGGNIRDTIEKGNITRRDIVDVFPFSNTIVTK
                     ELTGAQIKDVLEHGVKLYPEKSSAFLQVGGISYYFNPKQKEGERITSIQKEGKPLDLN
                     KKYVVATNDYIASGGDEFPCFSKEPILKEFGNLESAVIEYIEYKKEISKNVDGRIGIK
                     SKDELISKNHESDLILSENEKNINDNEENLSNNIKSSDSDKNKSLDKTSARESSNQGI
                     SKREAKEKSPKTGDLGFSNSIIIFIVSSTLICLLNFNQKELKDKKSK"
     gene            30894..31601
                     /locus_tag="PC466_001211"
     CDS             30894..31601
                     /locus_tag="PC466_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2768605.1"
                     /translation="MNNILLLEDDKSLNRGISFKLKKEGYNVFSAFGIEEAKNIFAKE
                     EICLIISDIGLPDGSGFDFCEEIRKKSDVYIIMLTALDEEVDIVTGYDLGADDYITKP
                     FSLMVLISKVNALMKRVNTVKNYTLLVCDDLFFYYIENKLIIRTDDKEEEIILSKTET
                     KLLKYLMENSMQTLTKEQLLESLWDSSGNFVDDNTIAVNIRRLRQKVEKNPSEPKYIK
                     TVRGVGYMWGERSIKKC"
     gene            31595..32905
                     /locus_tag="PC466_001212"
     CDS             31595..32905
                     /locus_tag="PC466_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2768606.1"
                     /translation="MLKNMNLKDGLSVKDDYIMRRVIVYSVLSVLIVTLVFILFEYSR
                     LHKLYEHQIKNTQNIAGILIEKYPNDEIDIVNSIYNSDYSKVSTGEKAFKKFGYGLEN
                     KMSNDKNFSLYLKSFFKESFFIFLMMFIVVIGIIYYFIRYINKRLSKIYFIVDKMAQE
                     NYLKDTTESEETGYLVEYNEYFKEGTFSKINNCLYELNRSLKIKFIKLEKEKESVKSL
                     VTDISHQLKTPLASLKLYNTLLIEEKLEEDEANEFLLTNKASINKLENLINSLVNISR
                     LEISMINIKKEDNDIKNTILNAVKSVTPKAKSKSITLNLNEFNSRIIPHDKKWTEESI
                     FNVLDNAVKYTQVNGEINISVEETANFFKIIIEDNGIGIEKNEFNNIFKRFYRGSADE
                     IESVEGSGVGLYLSRKILEEQGGNIIVSSKVGIGSKFSLFLTTM"
     gene            33022..33705
                     /locus_tag="PC466_001213"
     CDS             33022..33705
                     /locus_tag="PC466_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2768607.1"
                     /translation="MKILYTENLSKHYGKGENLVRALDNVNLEINEGEFVAIIGKSGS
                     GKSTLLHMIGGLDIPTSGKVYIDNKNIFTLKEEELAVFRRRKIGFIFQSYNLIPSLNV
                     WENVVLPIGLDGREVDESFIKELLKSLGLENKHDVLPNTLSGGQQQRVAIARALATRP
                     AIILADEPTGNLDSKTSDEVMSILKSMSKKYSQTLVMITHDDSIAQMADRVIFIEDGR
                     VSKVGDKND"
     gene            33698..36085
                     /locus_tag="PC466_001214"
     CDS             33698..36085
                     /locus_tag="PC466_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HDF2768608.1"
                     /translation="MINTTKIAKSNLKQNKSKSILIIITIILSTLMLSSIGIYIVDAG
                     AYQKENTIKYSGNYQGILANVDEKQADILSNHADVELTGEMNGVGVEKLEDDSNISLA
                     YMNEDALKLNSFELIKGKLPTKENEIVLDSGALKALGYKNKDLGEKIKISYNDYKNDK
                     KIEKEFVISGILKTSEISEAGKYYYAIISELYMRNTRDMSQEDFNIYVKFNDKSNLSI
                     EQAKEKLDKIANDIGLDTINTAVNENYINALKPDMETIMGGGFVGLVIVLSSILVIYN
                     IFYISIVTKVQEFGKLRAIGATKKQIKNIVFKEGFILAGIAIPIGIILGYVLANIIIK
                     SFMDIDVKSSRLPVILSVVVISFISVVLSLLKPMKVASKVSIVDAVRYTGNKISNKSK
                     RKGYKNINLKRLSHANLERNKKRTYMTLASLILSGTIFITVSTALESFDAEKMAREHF
                     PYDIEVRLSGYEMNSDKNPKNNLNILQMDNPLSKDFFNQIKNMEGIKRIESARSVKIG
                     MEDYDVEFKYDLLQSINENDVKSLNKNLIDGKINLERLQTGDEIVITHVDTAKEMGVK
                     AGDKIRLTLYDGDKKIKKEFKVQAIAMGVPSFGIGKDFIDRTLKYDSTSSLGIYTEEG
                     KYQEIKDSIKKIAKNNGFLETDFIDSRIESNKAVISFIKIMGYTLTGIIGVIGFMNLV
                     NTMITSIVTRKKELGMLQAIGLTNKQLVKMLNSEAMYYTSGMMIGSILFGGILGYIAV
                     IFLKKTGLSYATYSLPIVPILLMIVCILIAQFITTYLIGRSFNKESLIDRVRYSE"
     gene            36364..37506
                     /locus_tag="PC466_001215"
     CDS             36364..37506
                     /locus_tag="PC466_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--glyoxylate aminotransferase family
                     protein"
                     /protein_id="HDF2768609.1"
                     /translation="MNKKINYAPGPTETRENVRLARAEKTTNPDIDIDFVEFYKKTCE
                     KFGNIVGTKNDVYILSGEGILGLEAACASLTEKGDRVLVIDNGIYGEGFKDFVTMYGG
                     EYVLFSSEYTKSIDIDELKAFLDEDSNFKYATVVHCDTPTGVLNDVSKICPLLKEYGI
                     LTVVDSVAGMVGERLSVDESKIDIILGGSQKAISAPAGLTIVGISQDAKNCIKNRKTD
                     VIGFYCNLNIWEGYYEKKYFPYTMPISDIMGLDKALDNILEEGIENVLDRHEKIAYSV
                     RKSIEEYGLELFLEEGYSNTVTAIKIPESIGALKLTDYMLKNYNTLVATSLNQYMDTI
                     LRIGHMGENANLNKIEHVLNVLDKSLSALGFKGNENLLNLFNKYYF"
     gene            37525..38049
                     /locus_tag="PC466_001216"
     CDS             37525..38049
                     /locus_tag="PC466_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HDF2768610.1"
                     /translation="MEVTAKQKFTTKDMVETSLLIALVFIATKFINIRLPISINGGLV
                     HLGTAMLFISAIVFGSKKGALSGAIGMSLFDLISGWTLWAPFTFIVRGVMGYLLGKIA
                     WANGNNGNNFLINVIGICVSSIWMLFGYYITEVILYGNFIVPLTSIPGNLMQVLIGLI
                     IALPISKVLKKCIK"
     gene            38149..38967
                     /locus_tag="PC466_001217"
     CDS             38149..38967
                     /locus_tag="PC466_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDF2768611.1"
                     /translation="MLSVTRYSIKNVRLKPWVKFIWYFETKSNILLNNKLLPTDSIDI
                     ILNLSDVMEYKIENQDYTASNMHFNGIRDKHGFIIQHGNIRVIGISFYPFGLYPFLKI
                     PISEFNRQIVDLEAVSELFAKKLEESLNPTQSVEKIVLYLEEMLLSILEEDLISNKSV
                     KLLNSFIYDNRYSNIKAFCDNTNINIKTLERICLKYTGYTPKILKRIYRFKMASSQLI
                     YNYKDNELFDFIYENEYYDQAHFIKEFKKFSGTSPIKFIGENKTIKENIKYNYL"
     gene            39045..39356
                     /locus_tag="PC466_001218"
     CDS             39045..39356
                     /locus_tag="PC466_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HDF2768612.1"
                     /translation="MKIITEIVEFNVEENLSKEEFIEIVNDLELKFHSIQSGFIDTEL
                     LYDEKSQKWIMIQHWESIEDLKSASSKMFKDSSTEKFRKALKNQTVKMNIIPQIKSWK
                     L"
     gene            complement(39659..41662)
                     /locus_tag="PC466_001219"
     CDS             complement(39659..41662)
                     /locus_tag="PC466_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha amylase C-terminal domain-containing
                     protein"
                     /protein_id="HDF2768613.1"
                     /translation="MKSQKRFKILDIDVYLQPFESDIKKRMKHYEDMKSKTLKNYKDF
                     SSFANAHLYYGFHQTNDGFFYREWAPNADSLSLIGDFNNWNRKSHPLRKIGSGNWEIF
                     IPGQNSLPHKSEVKVQVTANGKTFDRIPLYIKRVIQKDFGGFNGQIWQPKTPFIWTDN
                     NFDLKNITSPLIYECHIGMSTESESIGTYNEFTEKILPKIKKAGYNTIQLMAIMEHPY
                     YASFGYQVSNFYAISSRFGTPEDLKNLINTAHSMGIAVLLDLVHSHAVKNTLEGINEF
                     DGSEHQFFHSGSKGNHPAWGTKLFNYGKPEVIHFLLSNIKFWLNEYHFDGFRFDGVTS
                     MLYHNHGLGVSFDSYEKYFSMNTDIEAITYLQFANELIKEIKPNSISIAEDMSGMPGM
                     CIPIKDGGIGFDYRLAMGVPDFWIKTISNLSDEDWDLGKMWYELTTRRPGEKNIGYCE
                     SHDQALVGDKTIIFWLADKEMYWNMEINSNNHVINRAISLIKLIKLITFSLAGEGYLN
                     FMGNEFGHPEWIDFPREGNNWSYKYARRQWSLSEDNNLKYKQLLNFDKSMLELTKYSD
                     IFIQNSHELIHMDNDKKILVYSKGKYLFIFNFHPNLIQSVDISKFQNTNYKTILNTDM
                     VEFGGNTKKENLRDYDVYFSSTPPSSKMPIASRTAIVLLDNGI"
     gene            complement(41815..42453)
                     /gene="recX"
                     /locus_tag="PC466_001220"
     CDS             complement(41815..42453)
                     /gene="recX"
                     /locus_tag="PC466_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HDF2768614.1"
                     /translation="MGIITKIEQQKRNDDRVNIYVDDKFFIAIFKELVYTFNLKKGNE
                     INEEELKPILDDEMYIKAKNKALNILSHADQSEKKLKEKLSSEFDENIIERVIDFLKS
                     YNLVNDSVLAQKIVNTNVNLNKCGKNRIKQNLYNKGINRSTINEAVSELDKDTEFENA
                     MYLAKKRYERVKKEDKKKIYQKISQHLSYKGFDYDIIKRVLNKLLNFDEYDI"
     gene            42729..43418
                     /locus_tag="PC466_001221"
     CDS             42729..43418
                     /locus_tag="PC466_001221"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HDF2768615.1"
                     /translation="MRSENLVKMAELKNTEKLEKFNRHKGKIKIGILGGTFDPIHYAH
                     LATAEFIRDKYDIDKIIFIPSGNPPHKLCITTDKYDRYNMTLLATESNEDFLVSKVEI
                     ERKKRTYTIDTLKYLKKKYKNADIYFITGADAICSVEEWKDVKKNFELATFIAATRPG
                     ISLLRSQETIEKLTKKYNADIITVYVPSLDISSTYIREQLNEGKSIRYLVPENVENYL
                     YENKLYQYGDD"
     gene            43419..43991
                     /gene="yqeK"
                     /locus_tag="PC466_001222"
     CDS             43419..43991
                     /gene="yqeK"
                     /locus_tag="PC466_001222"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HDF2768616.1"
                     /translation="MNLENINQRLNQMLPVGRLSHSRNVAKCAEKLCEIYGCDKEKAY
                     LAGMIHDCAKYLSDKEIEDYVNKYEIYLDPIEDGNRSLSHSVIGAYICEYEFEVEDED
                     IINAIKYHTTGREDMSLLEKIIYIADLIEEGRKFPVVDTLRELAYGGKLDEALLTSFN
                     NTLMFVINKKEEIHPRTVMARNYLIKEKLL"
     gene            44108..44458
                     /gene="rsfS"
                     /locus_tag="PC466_001223"
     CDS             44108..44458
                     /gene="rsfS"
                     /locus_tag="PC466_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HDF2768617.1"
                     /translation="MTVEQMTKIAYDAIEDKLGQDTVIINIGKVSSLCDYFIITTASS
                     QRQVKAIADNVEDELAKLGLEPRGKEGQGTQTWVLLDYGDIMVHVFNEENRGFYNLEK
                     LWKDAPYIDIDTLA"
     gene            44812..47232
                     /locus_tag="PC466_001224"
     CDS             44812..47232
                     /locus_tag="PC466_001224"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HDF2768618.1"
                     /translation="MSVYNFKEVESKWQKIWKDNNQYKMDTAQTEKPNYYTLEMFPYP
                     SGKIHMGHVRNYSIGDVVARFKKMEGYNVLHPMGWDSFGLPAENAAIKHGIHPHKWTM
                     ENIEEMKEQLNLLGISYDWDKEVATSTPEYYRFTQEIFLKFLEHGLAYKKKSYVNWCP
                     SCETVLANEQVVQGACERCKATVLKKDLEQWYFKTTEFAEELLNDLDTLDGWPEKVKT
                     MQKNWIGKSTGADLVFDIDGTDKSMTVFTTRPDTTYGVTYMVLAPEHELVKELVAGTE
                     YEADVEAFVQKMHTMTEIERTAADVEKEGMFIGRYVINPLNGKKVPLWIANYVLVEYG
                     TGAIMAVPAHDERDRDFAEKYNLDIIDVITEDNKMINSEEFNGLDASEGFEGIIDKLE
                     KEGRGKRTINYRLRDWLVSRQRYWGCPIPVVYCDECGIVPVKKEDLPVLLPTDVEFTG
                     KGESPLTTSKQFMSTTCPHCGKPARREVDTMDTFVDSSWYFLRYVDSNNENEPFSKEL
                     VNRWHPVDQYIGGVEHAIMHLLYARWFVKAFKSMGMVDFNEPFKNLLTQGMVLMDGSK
                     MSKSKGNTVSPMDIIDEYGADTARLFVLFAAPPERDLDWSEQGVDGCFRFLNRVYRLV
                     DELADVVKKDVEFGELNSQDKDMRYTIHSTLKKVTADLSEKFGFNTAISALMELINDM
                     YKYKELDNINEAVIKEGVQTIVTIIAPFAPHLGEELWTMIGKEGSVFDIDWPKYDEKA
                     LVKDEIEVVVQVNGKVRGKLTVNSNISKDEMEKVALEDEKIKGLVEGKTIVKVVAVPK
                     KLVNIVVK"
     gene            47659..47971
                     /locus_tag="PC466_001225"
                     /pseudo
     CDS             47659..47971
                     /locus_tag="PC466_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431045.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            48070..48738
                     /locus_tag="PC466_001226"
     CDS             48070..48738
                     /locus_tag="PC466_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HDF2768619.1"
                     /translation="METVSNNQSSVEIQLSLFEAIKDLLLINPIFLLGIILIGIFLVV
                     IFKKNSDIPKVKTSILSLAMYYYLCLTLSHIVGIPTFSEYIRLSQLGETFFNPNINLI
                     PFSDGFSLSFILNILLFVPLGFLCPLISKTFERLRNTFLIGFGLSLFIETIQLFTLHR
                     ATDIDDLLTNVIGTIIGYFCFKLIAKLRIVKLHSDDDSMEQDYTVCIPIAIIIVALIL
                     GFFS"
     gene            complement(48896..49891)
                     /locus_tag="PC466_001227"
     CDS             complement(48896..49891)
                     /locus_tag="PC466_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HDF2768620.1"
                     /translation="MSIKKKVAIVFTGGTISMTVDDKVGAAIPTLSGEQILSMVTNID
                     KVADVEVFNFDEIPGPHITPYRMMELKNYVNDLLARKDITGVVITHGTDSLEETAYFL
                     DLTIDNIKPVIVTGAMRSSSELGYDGSSNLSASVCTAVSKDAMGKGVLVVLNNEVLLA
                     SEATKTNTLSLNTFKSLTSGPLGIIDCNELVLTRDIVNRTIIDTDKVESKVALFKAYV
                     GENADFIRFAVDSGYKGIVIEAMGIGNIPPQMLSGVEYAREKGLPVVIVSRCHSGRVF
                     DSYGYFGSGRDLKNLGCIFGGDLPGQKARIKLILALGKTDNLDEIKDFFEKGIYC"
     gene            complement(50012..51640)
                     /gene="aspD"
                     /locus_tag="PC466_001228"
     CDS             complement(50012..51640)
                     /gene="aspD"
                     /locus_tag="PC466_001228"
                     /EC_number="4.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate 4-decarboxylase"
                     /protein_id="HDF2768621.1"
                     /translation="MKNHTYKEIKNIYGKISPFEFKDKLIDIAKYTAKENNRELLDAG
                     RGNPNWTCSTAREAFFTFGHFAITETRSNWDLGHLAGMPQKKGIKERFFKFINENIDM
                     PGAYLARDIINFGINELGFDGDEFVHELADGIIGDNYPLPDRMLPHMEKIVHDYLVQE
                     MKYDISGKYGDVEIFAVEGATAAMCYIFDSLMANELLKKGDTIALMTPIFTPYLEIPN
                     LPRYDFKVVNINANEVDEKGAHTWQYTKKELEKLRDKSIKALFVVNPNNPASIAMDEI
                     SCNNLIDVIENYNKDLMIISDDVYGTFVEDFSSLMSKLPYNTVGVYSYSKYFGVTGWR
                     LGTFALHKKNVFDKKINDLTGELKKSVDKRYSDMSLNPSSLSFMERVVADSRLVALNH
                     TAGLSTPQQVQMAFFSAFALIDKVDAYKKLNMSICHRRQKLLFEALELPINENKNNAA
                     YYTQFDIEEWAKLNYGEDLFKFISKTASPVDVLYKLANDYSVVLLSGNGFYGPEWSIR
                     ISLANLYDEAYTKIGKAIREILNGYIVEWQKIKK"
BASE COUNT        20070 a         5780 c         8912 g        17007 t
ORIGIN      
        1 attttatcca aaaacttttc taggtttaaa ttataccata tttatagtat gatatgatta
       61 taattttata taataaataa gtaaaaatag taaaaaataa attaagaaat gtttttaata
      121 aaaataagct taagggggtc aaccatgagt gcaaaggtaa cgaatcaata tggaaatata
      181 gaaatagata atcaagtaat agctcaagtc gtatatagag ctgcaatgga aagttatggc
      241 ttagtaggtt tagcatataa gtctaaagga atagtagagc tattaaaagg cgagaacgca
      301 actaaaggtg taagagttga ggaagtagaa gaagatgcca tagcaatcga actttatgtt
      361 ataatacaat atggtacaaa tatatctact gttgccaata atataataga tagagtaaag
      421 tatgtagttg aaaaaatgac tggcgtaaga gttactagaa ttgatattaa tgtacaagga
      481 ataagagtta agtaatttca taggaggaaa caaatgattc aatatataga tggtaaaagg
      541 ttaagggaga tgtttatttc aggtgcaaac aatctccaaa acaataaaga gttagttgac
      601 aagttaaatg tattccctgt accagatgga gatacaggaa ctaatatgtc attaacaata
      661 tcttatgcct taaaagaatt agcaaaagtt gaaaatgata atatatcaga tatcggaaaa
      721 gcattatcta aaggttcttt aatgggagct agaggaaact caggagttat actttcacaa
      781 ataatcagag gtatagctaa atctatagaa ggaaaaagta aattatcaac agaagattta
      841 gcaaaagctt ttaaaaatgg ttcagacaca gcatataaag ctgtaataaa accaattgaa
      901 ggaactatac ttactgtagt tagagaaagt ggagagtttg caataaaaac tgcgaaaaaa
      961 gagaaagatg tagtaaagtt tttaagtatg cttgtgaagg aatcaaattc ttcattagaa
     1021 agaactccag accttctaaa gaatctaaaa gaagctggtg tagttgactc tggtggaaag
     1081 ggtcttgtac ttatatatga aggaatgtta gcttctataa aaggcgataa catagaaata
     1141 aaaaatgttg acctagatac taatatttca acaagtatgg attttgcaaa gagtactact
     1201 agcacagatg atataaaata ttgctattgt acagaattta ttttagaaag ttctaaggta
     1261 gaagatacta aaataagaga cataatgatg gcttatggtg atagtctagc agtagttgga
     1321 gatgatggag tcataaaggt acatgtacac actaatgacc caggaaatgt acttcaagaa
     1381 gctctaaagt acggtcaatt attaactata aaaatagaaa atatgaagtt acaacatgaa
     1441 aatacattac tggatgtaga agaaaagaaa gaaaatgata gtgaaccttt agaagaagag
     1501 aaagagtttg ggtttatagc tacttctatg ggtgaaggtt tggcaaatat atttaaagat
     1561 ttcggagttg accatataat agaaggtggt caaactatga atccaagtac tgaagatttt
     1621 atgaatgcta taaagcatat aaatgctaaa aatatattta ttttcccaaa taacagcaat
     1681 ataataatgg ctgctaatca ggcaaaagaa ttgagtgata aaaatataat agttatacct
     1741 acaaaaaata cgcctcaagg atttgctgca ttagtaactt ttaatggaga attaagcgaa
     1801 gatgaaaata aagaagctat gatgaatgct ttaaactcag ttaaatcagg tcaagtaact
     1861 tttgctgtta gggatacagt gatgaatgaa attgatgtta aagaaggtaa tataattgga
     1921 attgcagaag gaaatttatt atcagcagga gattatgtgg atgaagtaac atcaaacctt
     1981 attgaaaagt tggttgatga agatactgct ataataacat tattctttgg tgaagatgtt
     2041 acagaatctc aagcaaatga actacgtact tctttagaag aaaagtttga agatgtagat
     2101 gtagagttat attatggagg acaacctctt tattattact taatttcagt tgaataatga
     2161 ttataagaac ctgtatgacc aagtagcttt tataaaattg gttgtacagg atttttgtgt
     2221 agtaggtgat atatttgttg gatttatata aagatgttca atatgttaag ggaataggac
     2281 ctaaaaaagc agataaatta aataaactgg gtatatttac actaaaagac ctattgtatt
     2341 attttccaag acaatttgaa gatagaaata atctaaagaa aatagcacaa ttagaagatg
     2401 gtgagaaagt tacgataaaa gcagtaatat caagtataaa tacatttagc ccaaaagaag
     2461 gtatgacttt aacaaagatt gatgtaaaag atgagacagg ctcggctaaa ttagtgtttt
     2521 ttaataaaag ttatataaaa aatacttttc gtccaggaga ttcaatatta gtttttggga
     2581 aggttaagaa aaaatttaat aacttagaac ttacatcatg tgaattagaa tatcttacta
     2641 attcacctaa gaatacatgt agatttatgc ctgtgtacca gcttacatac ggtgttacaa
     2701 ataaagaaat tatgagtata attagaacag tacttgaaga taaagaatta attatacaag
     2761 aatatatgcc acaaagaatt atagaaaaat ataggctatg tagtatagat tttgcagtta
     2821 gaaacataca ttcaccaagt agtaaggaat cattaaaaat agctttatat agaattgtat
     2881 ttgaagaatt acttatacta caactagggt tgtttgtatt taaaagtggc agaaataaag
     2941 aagatggaat aaagtttgaa acaagtaaag acttaaaaaa aataataagt gctttaccat
     3001 ttaaactgac taaagctcaa aacagggcat tagatgaaat tatacaagat atgaatttag
     3061 agaaaataat gaatagattg gtacaaggtg atgtagggag tggtaaaaca gtagtagctc
     3121 tcttagcact tgcaaattgt gttttaaatg gttatcaggg cgctttgatg gcacctacag
     3181 agatattagc agggcaacat tacatttcac ttactgagtc tctaaaagat tttggaataa
     3241 atgtaggtct attaataggt agtcttacaa aaaaacaaaa ggatacagta ttggaacaaa
     3301 taaggaataa tgagattgat atattaatag gtacacatgc actaattgaa gataaggttg
     3361 aatttaataa tattggttta gttataacag atgaacagca tagatttggt gttatgcaaa
     3421 ggagcaaact ttcattgaaa ggagcaaatc ctgatatatt agtaatgaca gcaacaccaa
     3481 taccaagaac tttagcactt atactctatg gagatttaga tatttctatt atagatgaac
     3541 ttcctccagg aagacagcca atagaaacaa ttgctattga aaaaagtaag cgagatagag
     3601 catataataa ccttgtaaga agagaggttg aatcaggaag acaagtgtac attgtatgtc
     3661 ctttggtaga agaaagtgaa gctatagaag ctaaatcagc agttgaactt gtagaggaat
     3721 taagagctga atatttccac gatttaaggc ttggattgct tcatggtaaa atgaaatcga
     3781 gtgaaaaaga cgaagtaatg gaacgtttta aaaataaaga aatagatatt ttagtttcaa
     3841 caacagttat agaagttggt gtcaatgtcc caaatgcaac attaatgata atagaaaatg
     3901 cagaaagatt tggacttgca caattacatc agcttagagg gcgagttgga agaggtagtc
     3961 ataaatcgta ttgtgtacta atttatgatt ctaaaacaga tgtatgtaga caaagaatgg
     4021 ctataatgga agagaccaat gatggtttta agatttcaga gaaggattta gaaataagag
     4081 gacctggaga attttttggg acaaggcaac atggtcttcc agaacttaaa gtagcaaact
     4141 tatttaaaca tataaaaata ttgaagttag cacaacaaga agctcgatat atattgggtg
     4201 aagataataa tctacaattg aaagaaaaca tggcactcaa aaaagaaatt atagataaat
     4261 ttaaagatac attgaaagaa atttcattaa attaatttta aattatgtta aaatattact
     4321 aatgtaataa tgtgctgaag ggagattgtc atattgagag taatttcagg aaaagcgaga
     4381 ggattaaaac taaatactcc aaaaaatgaa gatgtaaggc caactacaga tagagtaaaa
     4441 gagtctctat ttaatatgat aaattcatat ataatggaaa gtgaagttct ggatttattt
     4501 gctgggactg gttctttagg aatagagtgc ttatctaggg gtgccaagtc atgtactttt
     4561 gtagatatca gtaaggaaag catagatatt gttaagtcca atgtaaaaaa ggcaagagtt
     4621 gaaagtgaaa gtattatttt aaaccttgat tttaagactg caatagataa acttaaatta
     4681 caaaatagta aatttgacat aatttttatg gaccctccgt attataaaaa tatgtttata
     4741 gaagctattg aaaaaattga taattctaat ctattgaacg aagatggaat aatagttgta
     4801 gaacatgata cgaatgattt atttccagat aagatatgta aattggagaa aactagagat
     4861 aagaaatatg gaaatactac attaactttt tataagatgg aggcataata tggaaaataa
     4921 acctagaaaa gctatatttg caggaagttt tgacccaatt actaatggac atttagatat
     4981 tatttgcagg gcttcgaagt tatttgacga attacaaata ggagtattaa ataatcctaa
     5041 taaaaagggt ctatttagct ttgatgaaag agtaaaactt atagaaaaaa gtacaagcca
     5101 tttaaataat ataaaagttg tgacttttga tggtttatta ataaattact gtcaggaaaa
     5161 tgggattgga gcattagtta gaggtgtgag aagtggtgct gatgttgatt atgaacttca
     5221 gatggcacat atgaatagag agcttaatcc agatatagag actataattt taccaagttg
     5281 tacaaaatat tcatttataa gttcatcttt aataaaagag gttttgctct ttgatgctga
     5341 tataaaaaat ttggttccaa agattgtttt ggaagaatta aagaaaaaaa ctagtggggg
     5401 taattgatat atgaagatag atttagaaat gattgaacta tttgagcagt tagaggagat
     5461 atttagaagt gcttctacaa tccctttctc acataaatgc acagtggata aagatgaggt
     5521 tttagcaata attaatgata taagaacttt aataccagaa gaagtaacac aggcagtatg
     5581 gattaataaa gaaagaaata aaataataag tcaagctaag caagatgcta caaatatagt
     5641 tgaacaagcg aaaaaagaag ctgagagaat acaacaagaa tatcaagata atatagagga
     5701 attaaagaaa aattctgaag atgtagtaaa ggcatatgta gaatccagcg aacctgttgt
     5761 tcaagcagac caaagagcaa aagatatagt tgatagagct gagagaatag ccaatgagat
     5821 aagaattggg tcaattgaat atgcagagga tgtgctttct agtgttgagt ataatttaag
     5881 agaaatatta gaagaagtaa aaagagataa agctgaactt agacctaaaa aataaatttt
     5941 aaataaataa aaatggagct atcacacaaa aaattccaat tgatgtgtga tagctctctt
     6001 ttaatatagc aattttttgt tatataattg tgctttttag attacttata tcttattttg
     6061 atattataat gtagcttaat cttttatttg ttgaaatcaa cttatttatt tgtataaata
     6121 atataggtta ttttcaaatt tttttaataa ttttaccact gtcttctttt agattagggt
     6181 tagactgtgc aaaattataa aataatacta aatcatgtgc aattatttgg tatggcacta
     6241 catgtagaaa atatagataa taaaattaag gaggtagtat gaaggaaagg gctaaaaaaa
     6301 tattagattt tattattaaa aataacaatg taacatcaca agaactacaa gaaaggttta
     6361 atgtttcaaa gagaactatt tattacgata ttctagctat aaatgaacaa ctaggaaaaa
     6421 gtggtaatat aaaaaatgta aaacacaaat ttatatttga aggtaattta tgtgatgcaa
     6481 ggaaaataat ttcaactgaa gaagataaat ttttagatag tgattacaga aaaactttta
     6541 tattaaacaa gatattactt ggcgaaaaaa tatcaataga aaaactaaca aatgaaatgt
     6601 tactttcaaa aaacacagta gtacaaacaa taactgatgt aaaaaaatac cttcaaacaa
     6661 tggggttaag attagagtat aagggaaagt acaaaattat aggtgatgaa tacgttatta
     6721 gagagctgtt tctgataatt gttcaagaaa atgtactgga aattaattct ataagtaagg
     6781 aagtaagtag tttcgataca aaaggacata taaaacttac tgattattct ttattaaatc
     6841 taactaagtt tgtggaattt ctaaataaaa ggataagaga tgggaaaaca ttatactcat
     6901 ataaatatct aaatgaagct aaaaaaatta gttactttag taattgtaaa gaacttttat
     6961 gtgaagaagc caatgaaaat gaacaagcct atatatgcac ttacataagt tcacttccta
     7021 gcttaaatag tgaagttaag gaagatgttg ttgaagaata tgtagataaa cttatagata
     7081 agtttgaagt aaatacagca ataaaattag aaagtaagca tgagtttaag aaaaatattt
     7141 taaggcacct ccactcttct tacaacagaa tacgatttaa gtttcctatt agaaatccaa
     7201 tgttagatga gactaagtat aaacatgagt cactttataa aattataaaa tcaattatag
     7261 aaaatgaaga agagtttcct gtatttgagg ggataagaga agaagagata ggatttatag
     7321 cagcgtattt tggagggtat ttaagagggt ctagggataa tggcctaaga agaaataaag
     7381 tcttactagt ttgtcctaat ggtcttatgg tatcaaagag tttggaaata caactatata
     7441 aatacatacc aaccatagaa atagtaggta tagtgtccat taagcaacta aaagaagtaa
     7501 atgtatacta cgattacata attacaacta tagatataca aaatgtaaac aatgtaattg
     7561 ttgtaaatcc tcttttaaca tcatcagatg ttcaattact tatgaacaaa ctaataagtg
     7621 taaaagaaaa cgagaagtat ttcaatcttg aattaataat acaagctata agaaaaaatg
     7681 gagttatcaa taatgaagaa gcactaaaag ctgatttatt aaacataata cacaagatag
     7741 atgaaggaga gatgtatcaa ccaatgttaa aggaattaat taatgcagaa agggtcaata
     7801 taataaaaag tgttagagat tggaaagaag caataaaaat agcctcaaag ccattgttag
     7861 aagataactc tatagaagag ttatatatag aaaatatgat aaagtcagtt gaaaaatatg
     7921 gaccatatat tgttttagct gatagatttg ctctaccaca tgcaagttct aaagaaggag
     7981 taaacaagct tgctatgtct ttactaatag tagaagatga agttgattta ttaggaaaac
     8041 cagtaaatat atttatggta ttagctgctg tagataacac tactcacatt agagcattag
     8101 catcactatc agagatgatg tacgaggaag aaaatgtaaa actaataatt aatggtgata
     8161 aaagttcaat actagaactt ataaataagc aaaattagga ggaatgaaaa atgaagatat
     8221 tagcagtatg tggttttggt gtaggttcat caatggtatt aaaaatgaca atacaaaagg
     8281 ctctaaagca gttaggtata gaatgtgaag tagaaaatac agatataaat tcagctagag
     8341 gtgctgattg tgactgtata ttcacaagtc aagaattgtt aaatgaatta aaaggaactt
     8401 gtaatgtaga tgtatatcca gttaaaaagt acatggattt agcagaagtc acagaagttg
     8461 ttcaaacttt tttaagtgat aaaaatgata agaaatagta taagttttaa aaagtaaatt
     8521 taagttaatc agaataaaat aaaaacttac taaattcaaa aatagtaaga aagagaggag
     8581 ggatttagtg gtagaaaact taaacagttg acctatcact aaaaaatata atgcttgatt
     8641 ttatttcaaa taatatttta cgtaatccat ctatgttaat tggattaata gcagcatttg
     8701 gtcttgtact acagaaaaag aaagcatctg atgttataaa ggggtcacta cttgcagctt
     8761 tcggaattat aattatggag actggaacag gtatgttagt tagttcaata gcaccaatta
     8821 atggagcttt ccaaagtata agtggtggtg cagtaacaaa aggtttaagt gatgttactt
     8881 ttactgcaag ttatggtgga attataggtt tagcaatgtt tgcgggttta gctattcacc
     8941 taatgatagc aagatttact cctattaaga caatcttctt aacaggtcac atgctttatt
     9001 ggttcccatt catatttgta gcttcaggag ttgaagctgg attaaatggt ggagtattaa
     9061 tagcttttgc agcagtatta tcagcactct attggtcaat aatgccttgg ttattaagaa
     9121 aatatgtgtt tgatgttata ggagatgatt cttttacatt aggtcatcca tctggttgtt
     9181 tagcacttat atcaggattt gttgctaaat tagtaggaaa taaagaaaaa tctacagaag
     9241 atataaacat acctcaaagt ttatcatttt ttagagaaat atctataagt ggtggaatgg
     9301 cagtgttttt aatgtttata gttgttggga tagtaatacc aggtgcgttt aaagatagta
     9361 atgagtttat tggaacgtat gcaataaagc aaggtctttc ttttggagca ggtcttataa
     9421 taatgcttca tggggtaaga atgctaataa atcaaataat gccagcattt caaggtatat
     9481 ctgaaaaagt tgtgccaaat gcactacctg cttttgactg tccaatatta tttaattata
     9541 aaccaaatgc tgtattaata ggattcttag ttgctatgct aacatctaca gctatgattt
     9601 taatatgtaa ctactttaat gtatttaatt tgctacttat accacttgtt ataacttcat
     9661 tctttgagtg tggagcagca gcagtaatag gagaatcaca aggtggtata cgtggagcta
     9721 taataggtac agctatagct gcaatattta tggtagtttt agtaggaata tctgctgtaa
     9781 tttactcagg aactattcaa aattggatac taatatttgg aggtaacgac ctttcattat
     9841 ttggtataat tagtaagttt ataggttcac tatttggagg aatattatag atatgaaatt
     9901 taaatacata gatgagataa gaagattaat tgatataata gaaaacgaag aaaaagtcaa
     9961 tatggaaaaa gcagtacaaa tccttgttga agcaatagaa agtaaaaatg ctatattttc
    10021 atttggagct tcacatgcag gaatattaac agaagaatta ttctatagag caggtggctg
    10081 tgttcttata aatccagtat ttgcaaaatc tctaatgtta gatacagcgc ctataactca
    10141 cacaagtaag atggaaagat tagaaggata tggtacagct ctagctgata aaactccaat
    10201 taaaaaagga gatgtagtta tagttcattc agtatctggt agaaatccag taagtataga
    10261 gtttgctatg aaagctaagg aaaataaggc aatagtaata tgtataacta atttaagtta
    10321 ctcaaaaagt gtatcttcaa gacattcttc aggaaaaaaa ctttatgaag tatgcgattt
    10381 agtgatagat aatcatggtc aaaagggaga tgcctgtgta gagatagatg gattaaacca
    10441 aaaagttagt ccaacttcta ctgtaatagc aactactgtg atgaactcta ttatagctca
    10501 agctactcag gaattagtta ataaagggct aaagaatcct ccgattttct atagtgccaa
    10561 tattgatggt ggagatgagt taaataagaa gatttttgat gaatataaaa gtgtaattca
    10621 ttatgaatat taaggttaaa aaaatatgtt aatgaacttt gaagtttatc aacaaagaat
    10681 attaataata tataataaat gctatcattt aaaagctgta ggtaaaaatc tacagctttt
    10741 tattattgta gattaaaaag atgcgtaatt aaattttaaa ttggagaaaa taaattggaa
    10801 ggtatcaatt ataaatatta gaaacgttgt catagaaaaa aactatatta aaaaaaagta
    10861 catagaaaaa actgattaga caataaatac atgctttgat aatattttaa atggagtgaa
    10921 aatgtgtaga attataatga aaaaagaaaa taaaaatgaa aaaagaaaat aaaatggagg
    10981 gaataaaagt gggtatgtta aaaaaattat gttcactagc tatggtagca attatgacta
    11041 caacacttat aacagggtgt tcaagtggaa atggaaaaga ttcaaaaaag gatggcgaaa
    11101 aagaaaaact agttctttgg atgccaccag tagaaaataa tatgaaggaa gtttgggacc
    11161 ctattttaga taaatttgag gaaaaaaata actgtgaagt agatttacag ataattcctt
    11221 gggataatta ttctgaaaaa tttgcaacag ctataagtgc tggcgaaggt ccagatgtag
    11281 gatatatgta tgcagaaatg tatccacagt ttatagaaag tggagcagta gaagatttga
    11341 ctaactatgc aactaaagag gataaagagc aatctattta tataaaaaca tctgaaatga
    11401 tgggtggaat gtatggtatg ccattccaag cagcaaatcc aggggtatta tactataaca
    11461 aggatatttt agagaaatta ggagagaaac ctcctaagac atgggaagat tttaaaagaa
    11521 tttgtaaaaa agcaacacaa gatactgatg gtgatggaaa gatagaccaa tggggattag
    11581 ctcagggatg gggagctaaa acttttggta acttaaactg gaactggtat ccttatttat
    11641 ggcaagctgg tggagatatt tttaatgatg atttaaaatc ggttaaattt aatgataaga
    11701 gtggtttaga agcagctaat ttcttaaaag aattacaagc atatgtgcct gaagattctt
    11761 tatctaaaga tagtaatgaa atgatagaaa gcgtatttgg accagggaaa gcagcattta
    11821 caataatgtt atcttctgct gcaacaagtg tatttgatga atcattcccg gatttaaatt
    11881 gggggtttgt aactggacta gaagataaga aagcagcaac ttttggagca gtagaccatt
    11941 tatctttaat gtcatctgct aaaaataaag aacttgcata caagttaata caacatatgt
    12001 taagtgttga atcaatgaca gaatttcata aagcaatacc aagagcacca ataacaaaag
    12061 gtgaaccata tcaaggtgat gaaagattca aagaaatggt ggaaaatgac aaaaatgtat
    12121 atagaccatt agtagtagga cctcatggag ttgaaatata tgaatattta tggaaagaac
    12181 ttcaaactat gatttcagga gataaaactc caaaacaagc attagatgat gctgcaaaat
    12241 attcaaatga tttattagca caataaaagt ttaaagctgt aatatgttgt aaaggacttt
    12301 acagattaaa attagcattg tatttataaa tacaatgcta atatttatat tggagaggat
    12361 aaaatggaaa acttagttag agagtttgaa gaaaattcaa aaagaaaaaa aacaaaatta
    12421 aatattaaac catatatgta tatattgcca ttgggaataa ttttagtggc gttttatgtg
    12481 ataccaataa taatgtcaat atactttagt tttacaaagt ataatattat tagtccagcc
    12541 acttttatag gtttagaaaa ttataaaaaa ttatttacag atgaaacatt aaaagtatct
    12601 attataaata ctattaaatt tactgttgtt gtagtacctt gccaaactat attatcattg
    12661 attttggcag tttggattac aggaaaagga aatagtaaaa tagcttcatt tgctaaaggt
    12721 gctatattta taccagtatt atcatctatg gttttgatag gtatggtatg gagggcttta
    12781 ttgaatggag aaggttctat tatatatcag gtattaggtg cctttggaat agaatcatct
    12841 aaacttttag gagatagtaa gacagcatta cctacactta tgtttatatc tatgtggaaa
    12901 aatatagggt atttcatggt aatttatatt tcagctataa tgaatttacc aaaacactgc
    12961 tatgaagtag cgaaggttga tggggctaca aaacttcaag aatttataaa aataactgta
    13021 cctttattga aaccaactac aataatggtt gtatttttag ggtcgatatg gtcattacaa
    13081 gtatttgact taatttatac tgtgacaggt ggaggtccag gtatatctac tatgagtata
    13141 gttatgcatg catttaactt aaactttaaa aactttaatt ctggatatgc aatgactgta
    13201 gcaaacgtat tatttttgtt aatagcagta gtttcgattt tacaaaataa gcttgtaaaa
    13261 cgagacaatt cagattttta gaaaggtagg tataatatga aaacagcaag aagattatta
    13321 agtgatggtt tacttttatt tatagcgtgt gcaagtttgg taccttttat atacatgttg
    13381 ataatatcat tgaagataac atataactca tatagtttgg atatatcttt ttcaacagta
    13441 actcttcaaa actatataga tatctttact aaaaaaggat ttgcacaata tttttttaat
    13501 acagcaatag tatctttttc aggtgtatta ttaaatttag tatttagtac attagcagga
    13561 tattcttttg cgaagatgga ttttaaaggt agtgataagt tatttttatt tatgataatg
    13621 actttaatta taccttccca agttacaatg ataccactat atataataat gaaacactta
    13681 ggatggataa atagttatct tgcacttatt atgccaatac caactgcatt tggcgtattt
    13741 ataatgagac aagctatttt aggagtacca aaagagttat tagaatcagc aaagatagat
    13801 ggttgctcgg attttagaat tttaatacaa atagtattgc ctttaatcaa accagcatta
    13861 attacactag caatatttac ttttatggga gcatggaacg agtttatgtg gcctcttata
    13921 gctacaacta aagatgcaat gagaacatta acagttggat tatctactct taagacattc
    13981 cagataacta attatggaca gatgatggca ggggctacaa taacattttt acctccattt
    14041 attttctatt tgattttaca aagtaaattt gttgaaggtg tgtctttgtc tggtataaaa
    14101 ggttaaatag tctaatttaa taacataaaa gaaacttata taaatatgga ggaatttaaa
    14161 ctatggaaat ttcatatgta ctgaaagatt gcacattcaa acacaataaa tactcagtta
    14221 tagaagctga aacttggaaa gagaaggatt tggatattgt agtagctaaa ggtgaaaaat
    14281 ttgcatttca aattatgcta aaagcaacag aagaatttaa ttgtacaatt gataaaagca
    14341 gtactatatc atggaaagga ctggaaaata gagtaagatt agcattaaat gtgcctaata
    14401 gtttagaaaa taattttagt ataaatatat taggatatgt tcaagatgat acaaaggcat
    14461 ttgtgaatga tgctatttta agggataaag atgtgttagt agagcaatat ttgcctcaaa
    14521 cattttggat tgaaggtcaa gtaccagaag attttgaaga aaataacctt aatataggta
    14581 ttgatatatt taaaagcttt ggatatgaag atgaagaaaa agtttgtaca attgatgttc
    14641 ctgtaaaagt aagaaatgtc gtgctaaagc ctttagataa aagcaagttc tttttagatt
    14701 tatggcaaca tccaagttgt ttagctagaa tgtataaagt tgagttatgg tctgatatac
    14761 attttgaaat agtcgataac tatttaaaag aattagcatc tttaggagaa aaagttgcaa
    14821 cagttatagt ttcagattat ccatgggcag ggcaaagttg ttataaagtt tataaaaatc
    14881 catcaaacct atatgaatat aacatggtaa gtgtatcaaa aggattggat ggaaagatta
    14941 aatgtaactt tgagagtatg gataggtata taagcatagc tgataagtat aaaatgtcta
    15001 aggagataga tttatttggt ctattaggta attggtgtgc tggtgagttt ggaaatcctg
    15061 tagaaggtta taaggaccct ataagagtaa gatattttga tgaaaatgat aaagtattta
    15121 aatttataaa caatacaaat gatttaaaag aatatatagg attagtatta aatcatttaa
    15181 tagagtgtgg attatgggat agagtaagga ttatagctga tgaaccaaat aatccagaag
    15241 tagtcaaaga gtgtatagaa tttataaatt ctactgtagg tactcatcaa gttaaatata
    15301 aatcagcaac tcacgaccaa aactttttag atagagctaa agatgaaatt gatgatatgt
    15361 caataaattt aaaacttact atacaaaatt ataaagatat agaaaatctt aagaaaaaaa
    15421 tcaatgacaa gggtgggata ttgacttggt ttgtatgctg ttttccagag aaaccaaata
    15481 gttttttaag ttctcctttt gtagaaaata gaataatagg atggtatact tattactttg
    15541 gtcttgatgg atttttaaga tgggactata atttatggac agaagaccct tggaaagatt
    15601 caagttacaa attccctatt tggaaagctg gagatatgtt ctttgtttat cctggaaaag
    15661 atttaaagcc agttagaagt gtcagaatgg agaatttaag atttggaata caggactttg
    15721 agttatttac aatgttagaa aaagaaaagg gcagagagta tatagaagtt gagcttatgc
    15781 aagaattatt aaataaaaaa gaaaatgctg aaattaaagg ttttggtgac atagaattag
    15841 gatattcact tgataattgg ggatatgata aagttaaaaa atatgtatta gagttgttag
    15901 acagagtata aaaaaatata agagtgtctc aaaatgaact ttttagttca tgaggcactc
    15961 tttttgtatg aaatcaatat agtttcattg tttcaacaat gaaaaatagg attacttata
    16021 ttctaagata gccctttagt tttttagttg tattcaatgt tttaaaacta actataaacg
    16081 ctataaagtt tataaatgac aataattata tgtaacatga tgtactttaa tttgctataa
    16141 tagggattga ataatattat atggaagata acattgtttg gggggattaa tataaaaaga
    16201 ataggtatta ttataatgtt ttttttaagt atagctttta ttggatttta tcttgcaata
    16261 agaggtaaca gtgatacagt taagatgcaa cgagggataa atataggtaa tgcactagaa
    16321 tcacctaagg attttccgtg ggatgtaaaa atgtcaaata agttttttga tgatataaaa
    16381 gatgcaggtt ttgacacagt acgtatacca gtaaggtttt ctgattatac gtcagattct
    16441 gataatttta aaattgatga agaatttttt aaaaagattg ataaatatgt agattatgca
    16501 ttggataaag acttaatagt tgtgttggat ttacatcatt ttgaagaaat tatgaaagaa
    16561 ccaagagttc ataaagaaga gtttttaaaa atatggcaac agatagctaa taggtatcaa
    16621 aaatatgata aaaaattggt atttgaatta ttaaatgaac ctaaagaaaa tttatcttca
    16681 caattactaa acgaatacat tgaagaagca ataaagataa ttagaaaaac taaccctaaa
    16741 agaactatta tagtgggacc atataatttc tatcaaattg attatttgaa tgaattaaat
    16801 gttccaaaag attctaatat agtagtttct tttcactatt acgaaccaaa tgattttgca
    16861 tttcaaggaa acatttatca taatggattt gagcacttga gcaatattac ttgggaagga
    16921 acaaatgaac aaatggatta tttaaaaaaa aggtttgata ttgtagaaaa ttgggcaaat
    16981 aaaaataagg taaaaatatt cttgggtgaa tttggagtaa caaaagaagc accagaagct
    17041 tcaagaagag cttggataaa agctgtaaga gaagaagctg aaaaacgaaa cttttcatgg
    17101 gcttattggg agcttgcttc tggatttggt atatacaatc aaattgaagg gacttgggat
    17161 agagacatat taagtgcatt aatagaaaag aggtgatttt atgaagaaaa attcaaaaaa
    17221 gatacttata actttaacta ttattactaa tatcgtatat atattgtgga gaatttttta
    17281 cacagtacct aaagaagaag ggatgtttgc cttaatctgt gctataatac ttctttttgt
    17341 agagataatg ggtatgatgg aaatgtttgt acattattat ggtatgtcaa atattgagta
    17401 tcctgaaaaa ccagtcataa gtgaagaact ttatccacat gtagatgtat tcattgcaac
    17461 atataatgag tctgttgatt tggtgagaaa aactgtaaat ggatgtattc atatgcagta
    17521 tccagataag aaaaaggtac atatatacat atgtgatgat ggaaatcgtg aagaaatgcg
    17581 tattctagca gaaaaaatgg gtgtaaatta cataactaga actgaaagag aaggagcaaa
    17641 agctgggaat ttaaataatg caatgcaaca tacaaactct cctttgattg ctacgtttga
    17701 tgcagatatg ataccaatgc atgacttttt aattgctaca gtaccatact ttttgaaaaa
    17761 tgagcaagct aaaaaagatg gagaaaaaga ggagtatgaa aaggttggtt ttgtgcaaac
    17821 tccacagagt ttttataatc cagacttgtt ccaatttaat ctgcactctg agggaaggat
    17881 tccaaatgag caagattatt tttacagaga tattcaattg gctagaaata ggacaaattc
    17941 tgtaatttat ggtggtagta atacagttat ttcaagggaa gcacttgaag aagttgatgg
    18001 attttatact tattctatta cagaagattt tgcaacaggt atcttaattc aaagtaaggg
    18061 gtatagatgt tatgctattc cagaagtaca tgcatcaggt ttatctccta cagatttaaa
    18121 aagtcttatt aagcaacgtg aaagatgggc acgtggatgt atacaaactg gtagacgtct
    18181 aaatattttg tttaggagag gtttaggttt ttggcagaaa ataagttata tttcttcaat
    18241 tacttattgg tatgcaagta taaaacgctt tgtatatata atggcaccta ttttattttc
    18301 tgtgtttaat gtgattgtag taaaatgtac attacttcaa gtattggtat tttggttgcc
    18361 aatgtatatt ttaagtagtt tatctcttaa aatattttct caaaatataa gaaatactag
    18421 atggaccaat atatatgaaa ctataatgtt tcagtcttta atgccagcag taatacttga
    18481 aacgtttgca atatctaaaa ataaattttc agtaacaaat aagaataaat tagaagaaaa
    18541 tagaatgtat aagtttttac agggaatacc ttattttatt tacatggtct tatctatcat
    18601 aggaatttta aaaatgtttg tagcaatatt taaaatgagt tcaatgacat attcagttgt
    18661 attattttgg ttgattggaa acctttttaa ccttgttatg gctacattat ttatatcagg
    18721 gagacaacag ttaagaaagt ctgagcgtta tattgctgaa attgatttta agttaaagca
    18781 aaactcttat gttctttctt caaaaacgat tgatatatca gaaaatgggt ttgcattttt
    18841 gctagaaaat ccagaatata tttccccaga agaagagttc gaggtagagt ttagagaaaa
    18901 atcaggaaat gaaatgtata tagctaatat gaaagcaaag attgttaatg ttgtggaagt
    18961 aaattcaaag tggaaatatg cagcttatat tacacatatt gaagatagtg aaatagataa
    19021 ttggatgtgt attgttcacg atagaatacc tactttaccg atgacaatat ctaatcaact
    19081 aggtttcttt gatgatttgc aaattaatgt aaaaaaacgt attgaaaaga ttagaacatt
    19141 atcacgaaga agtccaagaa tcaatatgaa ttttcagatg gatataaaaa atacaggtaa
    19201 attaagaata gtaaatttta attatcaata tgtattatta aattttgaga ataaaaatat
    19261 ttatcctaaa gaaatagcat tggaaattaa tgaaaatatt gtgttagaat gtgatttatg
    19321 tgagggtaaa atcgatgaaa gaggtctctt atataaagta aataacattg acagcataat
    19381 gcaaaatttc tttttaagag atgaaatgat ggattggata ttacaaaata agacaattcc
    19441 tgtttcaaat cctagtgaaa agaaggaaaa aagtatagat gagtttgaac ccatggaata
    19501 tatttaggag agatgaaatg aagactttaa aagtgttttt ttgttctgca aaatatctta
    19561 ttttggtgtt tatttttttt ataaatacta cttttataag ttcagcgaca agtgataaaa
    19621 ttttagattt atcctttaaa aagatagaga ctgatttaag ttctaggatt acatatgaag
    19681 atacaggtgt aaaaatagaa acagatagtt ctaaaagtga taaggaacgt tatttatata
    19741 tttaccaaaa tataaaagaa aattggagta tgtataataa tttttatatt gaaattcaaa
    19801 ataaaaataa aagttcccag aaaataaatt taagtataca aagtaagaat atgcttgaat
    19861 ttaggttaaa agaaggtagt gaaatatttt tggaagataa aaatataata tattcagata
    19921 aaataaaaga aggatgcata gaagtaccag gtgaatttga aggcaaaatt tatgtgaact
    19981 ttaatagcct tataaatgag aaaagtaatg ttgtgctgga ctcaagtatg ctttcaaaca
    20041 ttgttagttg gggaattaca tttattccat ctgatgaaga acataatatt gttattataa
    20101 aaaagatatc tttattgtct gaagagaaat taagtttttt acataatatt aaaataactg
    20161 gcaatgaaga agtacaaata ccagtattgg gtcaaagtat aagtcagtat gaggtattag
    20221 gtcttaaacg tgattctaaa attaagtatt ctcttatggg aaaacaagat aatgtgagca
    20281 tatctcaaaa tggtaaatta acattaagta ataaagccga acctggacaa attattttac
    20341 aagttaatgt tgatgataag tttaaaattg gaaggaaaat agcattaact gaatcttgga
    20401 gtattaataa aaaagataag gatggtgttc catatacatt ggtatctcct gagcaatcac
    20461 caacagtaca atatatgaaa aaaataaact ttatgaataa catcataacg tttgttcgaa
    20521 ttttatttgt atctctagta ataatatgct ttggaatata tttatattgg aaaaaatgtt
    20581 caaaaactaa gtaaagagag gaggttagat tgtgttattt tcaagtttaa tttttttatt
    20641 ttatttttta cctataactt tggttttata ttatgtattt aggtttaacc gaacgataca
    20701 gaacatgata ttgcttgctg ttagtttatt tttttatgct tggggagagc caaaatttgt
    20761 tgttatcatg atagtttcca taataatgaa ctatatattt ggtttactag tagatagata
    20821 tagggaaagt aaaataaaag taaaagtttt tttagttttg atgtgtgtat ataatatagg
    20881 tgttttattt atatttaaat atctagcttt tgcgctaaga aatattagtg aacttattaa
    20941 tactgaacta actataccta gtattgtttt acctatagga atttcatttt ttacatttca
    21001 gggaatgtct tatgttatag atgtatatcg tagacatgga gaagtccaaa agaatccttt
    21061 ttatgtggga ctgtatatag catttttccc acaattaata gcaggtccta tagttagata
    21121 tgagagtgtg gcagaacaaa ttctcaatag aaaagaaact tggaataaat tttctattgg
    21181 gacttgcagg tttataacag gtctaggcaa aaaagtatta atttcaaata acatggctat
    21241 agtagcagac tatatttaca ctatgaatag tcaaggagaa atagctgcat cacttgcatg
    21301 gcttggttca atagcctata ctatgcaaat attctttgat ttttctgctt attcagatat
    21361 ggctataggt ttaggtctta tgtttggttt taaatttgaa gagaacttta attatccata
    21421 tatatcaaaa tcaattagtg agttttggag aagatggcac atttctttgg gaatgtggtt
    21481 taagagctat atatactttc cgcttggagg ttctagagta gcaaataaag atattatgat
    21541 tagaaatatg tttatagtgt ggttatttac tggaatatgg catggagcag aatggacatt
    21601 tgtaatttgg gggattttaa actttgtttt cttgattata gagcgattta taatgtttga
    21661 aaagattgaa aatcacaatt ttataaaaca tatttatgcg ttattagtag ttaactttgg
    21721 gtgggtattg tttaggtcac ctaatttaaa agaagcatat aattatttca aagctatgct
    21781 tggaggcaat ggagttatat ggagtgatta tacatatatg tttttaaaag aatactgggt
    21841 tttctttata tttgcattta tttttagtgt acctattgca aagaaaatca ataagtttgt
    21901 tgttgaacaa gctaaatata gtatgatatt taacgtattt tatccaatct cagctatttt
    21961 attgttcttt atttctgtga catatttagt aactggaagc tataatccat ttatttattt
    22021 taatttttag ttgggaggaa aagtatgaat agatttttta aagtaagatt aataactgca
    22081 attatgttct taattatttt attcgctttc tctatcttta atatttgtta ttctggaaaa
    22141 gatatgatac aggagataaa aaattcagtt gctgaaaaaa gtagtttaaa agatacaata
    22201 tcatctattg ataacacagt aaatgacaaa gtaatatata aaaatacgtt cattgaaact
    22261 tatggctact tacaaaagtt aatgggtaaa aatgagtttt caaaatttag tgttgtaaaa
    22321 gatacttctg gaaagatgca ttatacatat tttgctaaag ctccaaatcc agttggtgtg
    22381 atagcagata gggtaagaaa attttctgag gaaatggaaa agcaaaacac taaattagtt
    22441 tacttaatga ctccagataa gtatataaaa ggagtgacaa aatttccaaa aggaatacct
    22501 tattcttata gcaatgagac agcagataat tttttaaatc aactaaaaaa gtataatgtg
    22561 gactatattg attttagaga aaatatttta aagagtggta ttccaaaaga tgatttattt
    22621 tttaaaacag accatcactg gaaagtagaa acttcttttt gggcatttgg agaattagtt
    22681 gagcaactta ataaaaaata caatatgaat ttagatgaaa atcattacta tagagataaa
    22741 gaaaattata actcaattgt atatcctaag tcatttcttg gttctatggg aagaaagact
    22801 ggtatcttat atggtggtat agatgatttt acattaattt atcctaaatt taagactaat
    22861 tatacttatt atacagattc taaatctcaa aaatttgaat taaaaggaag gtttgaagag
    22921 agtttaatat tatcatatcc ttttaatgca gaccttgatt taatggatgg tcaatcagat
    22981 aagtatttta catatttatt ggggaataga ccattagtta aaataaaaaa tatagaaaat
    23041 ccagatggat taaaagtgct gtttgttaaa gattctctaa ttgtaccaac agcagcattt
    23101 ttttcctctg tttgttcatc tatagatatg atagacccta gatattatga tggagatata
    23161 ctagaatatg caaaatccca tgactatgac tttgttttta tatctgtata tccccaaaat
    23221 cttacaaaag aattttttcc gttttgtaag taaatttcta aagaaatttt cttataaaat
    23281 aaaaaataaa tggctaacta gttaaaagtt agccatttat cttaagtgtt actctaagaa
    23341 atgttttttt taccaaatac ttctttatct atttttccaa gtgattttcc tacagtaatt
    23401 gatgatacca tagcaccatt aacatttatc atggtacgtc ccatatctag tatagggtct
    23461 attgcaagta taccaccaac taatggaaaa taagaaccaa gaccaactcc agagataaca
    23521 actgaaacgg ccattgtagc agttcctgga agaccagcta ttccaaacga actaattgtt
    23581 ataacaatta acaacataac ataaaggctc atatccatgt ttactccagc catattggca
    23641 agtgttacag ccattaaagc aggatatata cctgcacaac cattcatacc catatttgca
    23701 cctaaacttg ctgtaaagct tgatacaccc tcatcaactc cgtgattttg tactagactt
    23761 tctatcgtta caggcaatgt tcctaaacta gaacgtgaag taaatgccag aagtaaagct
    23821 tcagttgaat ttcttatata agtaatggga tttagaccat ttaaagttat aaaaattaaa
    23881 tgtatggtaa ataatattgc cactgatata taaagagcta atataaactg taaaacagat
    23941 actattgagc taataccttg tgaagttatt gtatttgcaa gcagagcaac cacagcataa
    24001 ggcataaatt taataacagt catagacaca cttacaatta ttttgtaaga tgcttctata
    24061 aaatctataa atggttttat tgtttcaaag tgttttttac ttaatctctt tattgaggta
    24121 gctataaatg tagcaaatat tattgtagct acaatatttc catttgccat agccattaca
    24181 ggattagatg gtagtaatcc tcttaaagta tccacaagag agtttatttc tttaagttct
    24241 tgattttcaa ctaaagtagg catattagct cctacaccta acttcattat atttgcaacg
    24301 ataattccaa caattgcagc tatagcagta gtagcaagaa gcatacctaa agatttaaat
    24361 gtcagagttc caagattgtt atctttcata tttataatta cttttataat ggataagaaa
    24421 actaaaggta ctactaacat ttttaataag tccataaatc cagaaccaaa taggctatac
    24481 cacttgctta cttcttgtag ccaagtgact tgagtggtat cattaggaaa accagcaaaa
    24541 gcttgtatta tgattcccaa tatgagtcct agtactgtag catatattgt tctcaatgaa
    24601 aattttattt ttttcttttc aaattgtcta acaataaaga atgtacctag aagtaatatt
    24661 atgaaaaaaa tcgttttaaa atctgtaatc ataagaaatt gtgataaaaa tgaactttcc
    24721 aatatttttt ctccttttat ttaaaaataa atttttctaa gtttaaatga taccaatata
    24781 ttaaaaaaat gtcaatatta tatcacaatt tacttaaata gagtaaaata aattgatttt
    24841 gaaaaatgtg attaagtata gaaaaatagg gtataataaa tgtttaaaga atttgaattg
    24901 tggtaagaaa ataaaaaata gcttttataa tatttgattt caaattaaaa tatgttaaat
    24961 aaataactaa aaattgttat gaaaaatgtt tacatagaat atatatcaaa tgaaaagctt
    25021 aaaataagtg aagaaattaa ctagacatca aaggagagat aaaatgagag tagtaataat
    25081 tggtggtgtt gcagctggta tgagtgctgc agcaaaatta aaaagaataa aacctgagta
    25141 tgaagttgtt gtttatgaaa aaactgaaat agtatctttt ggtgcttgtg gattaccata
    25201 ctttgttggt ggtttttttg atgatgctga tgaattatta gcaagaacac cagagaaact
    25261 tagagaagct ggaattgatt taaatatatt tagagaagtc gttgaggttg atagtgaatc
    25321 taagaaaata aaagtaaaaa atataaaaac agatgaaata tatgaagatt actatgataa
    25381 attgatgata gcaactggag caagaagtat tatgcctcct ataaaaaaca taaaattgaa
    25441 gaatgtttct acattaaaaa gtttatatga tggagaatat ctaaaaaaac ttttaagtaa
    25501 tgaagataat aaaagagtga caataatagg agctggtttt atagggttag aagcagttga
    25561 ggcatgtaag aaattaggta aagatgtaga tgtaattcag ttagaagata gaatattgcc
    25621 acaagtattt gataaggaga tgacggatgt attagaagaa gaaataaata gacataatgt
    25681 taatttgcac ttggatgaaa tggttgtaga actttgtgga gaagataaag tagaaaaagt
    25741 tataacaaac aaaggggaaa tagatacaga tgtagtaata attgctactg gtgtgagacc
    25801 taataccgag tttttgtcaa atactaatat aaaaatgcta aaaaatggag ctatagtagt
    25861 tgatgaatat ggaagaactt ctgtagaaga tatatactct gctggagatt gtgcaactat
    25921 aaagaatata gtaagtaatg aaaatgtata tgttccttta gctactggag ctaataaatt
    25981 aggtaggata gtaggagaaa acctagcagg aagagaagta tcttatcaag gttcactatc
    26041 ttcaagttgt ataaaaatta tggatatgga ggcagcatca actggaatta cagaaaagca
    26101 agctaaagat ttaggcataa atgtcaaatc taaatttatt tctgattata atcaaactca
    26161 ttattatcca ggaagaaata aaatatatgt aaaacttatt tatgatgcag atacaaaagt
    26221 tattttaggc ggacaagtgg ctgggtttaa ggatgctgtc caaagagcaa atgtattggc
    26281 agctgctatc tttggaaaaa tgaccacaag tcaacttgga atgttagatt tatgttatgc
    26341 cccaccattt gcaagaacat gggatgtttt aaatgtagct ggaaatgtgt ctaaataata
    26401 tttagattat agctaatata gttgacaagc aattaaggga atgaatttac ctaaactatt
    26461 tttatcatgg taaaattcat ccctaaattt ttattccaaa tttttagaaa taaggattcc
    26521 attaaattat tcatcaaaat ttaaacgcaa gcttaatcta tcttctccaa gaatagtatt
    26581 ttcaaaaaca ttagtagcat tttctaaata catactaggt atgtctaaag aaggactaaa
    26641 atgggtcagt aaaagttgtt tgacatttcc aagttttgca agattagcag cttctctaaa
    26701 agtcatatgt ttgtttctaa cagcttttga tatatctaaa tcatcaccat acatggcttc
    26761 acatataaat aaatcactat cttttatgaa atctggtatt gattctatag gtcttgtatc
    26821 ggttgtaaga cttatcttaa ctccctttct caattctcct aagaccatat ctggagtgta
    26881 ttgttttgaa tttaaaacta tattttgacc ttcttggagt ttgttccata atattttagg
    26941 aacttcgttt ttagttgcct tatctatatc aaatttaggg tttcttctaa aattaaaact
    27001 gtatcctaaa cactctatag agtgttctaa actgattgtt gaaatttcta aatttcttaa
    27061 aactttatta tctaaagaaa aattgccttg agggttttct ataattttta aagtgtatgg
    27121 tacatattct actaaatttc tcatagaacg tatacaatcg actattccaa ctggaccaac
    27181 tatagttaaa tcacttgtac gaccactatt cccaattgtt gataaaagtc ctaaaagtcc
    27241 aaatatatgg tcaccatgta aatgggttat acaaatcaag tctatatctt taaagccaca
    27301 tttttttagc ttcatagata cctgagtacc ttcaccacag tcaattagta tttttctacc
    27361 tttatagttt ataaatacag aggatagaaa tctgtttggc ataggtacat ttccaccaca
    27421 tccaagtaaa gttaaatcta tcattttttc ccctttctaa aattaacaca aatctgttgt
    27481 ttgtttttat tatgatatcc tattataatt attttaacat taaatataac aataaatgtg
    27541 tatttgagtc aagaaatatt atcaaataaa gtttttatat agcaatgtat aaaaatttgg
    27601 agaacgaaaa gtgaaaatta tatttaggag tatttaaagg aggaaaattt aatgaaagta
    27661 ttaaagaaaa ttactatttt gtcattgatt acattaacct tagttggttg tagtaacgga
    27721 gaagataaaa aagtggttga aggttctaag aaaattcaaa attctaaaaa agatgaacag
    27781 cctataatag tacataaaga tgcaaatata ttgaaagata ggtatgagcc accaaaagga
    27841 tttaaaagag ttgatgtaga aaaaggtagt tttgaatcat ttcttaggaa tactaagcta
    27901 aaaaattatg gagagaaagt aaagtattat gatggaagaa ttaaggaatc aaaaggtatt
    27961 tatgatagtg tatttgatgt tgatattggc aatagagatt tgcatcaatg tgcagatgcg
    28021 attatgctta tgagagcaga atacttgtat cagaataaac tatatgatga aataagtttt
    28081 gattttgttg atggttttaa ggcgaagtat tcaaaatggg cacaaggata tagaatttca
    28141 gtaaaagata gtggttcaag ctggtataaa gcaactgaat attcaacatc ttatgagagt
    28201 ttcagaaagt ttatggatat agtgtttgca tattcaggaa cgttatctct tgaaaaagaa
    28261 ttggagcctg taaaagttga ggatatgaaa ataggagatg tgtttatagt tggtggaagt
    28321 ccaggacatg caagtataat tatggatatg gcagaaaatg aaaagactgg taaaaaggta
    28381 tttatgatag cccaaagcta tatgcctgca caacaaacgc aacttcttat taatcgtaaa
    28441 aatccaaatt tgagtccttg gtatagttta gattttgaag gtgatttgac aatacctcaa
    28501 tggactttta aaagagacca gttgaaaaga ttttaaaata ataattttat ataataaaag
    28561 aaaaatatag atgtgaaaaa atgtaattag attaaaacta attggatatg gacaaaatta
    28621 aattgataga taaatattaa aaattacact aatcaatctt actatagttt aatatttatc
    28681 taaaaagttt tatgtaaaat ataaatttta tattaaagct aaaactaatt tgaggaggct
    28741 aatttatatt gaagattaga aggtatttaa ttttggtaat tataattcta attacaacaa
    28801 gtcagagttt tatttcttat gggctagagc gatttgaaga aataaccatt tttcacacta
    28861 atgatataca tggaagatat gctgaaggtg atgaccatat acaaatagga aatctagcca
    28921 cattgaaaaa agaaactcca aactcaattt tagtagatgc aggagattgt ttgcatggac
    28981 ttccaatagt aaatatggat agagggaaaa gtgcaattga attaattaaa tgtgctggat
    29041 atgactatat tactcctgga aatcatgact ttaattatgg aaaagataga ctgtttgagt
    29101 tatctaaaag tgctaattta ggagagaata ctttaaaatt tttatcatca aatatttttg
    29161 aaaatggaaa aaaagttttt gatagtaatg atataaaaga aatagatgga ataaaaatag
    29221 gattttttgg actctcaacc caggaaacaa agaacaaaac tggatttaaa aatgtggaag
    29281 gattagagtt taaaaatcct atagaaagtg caacagaaca agtaaatgaa ttaaaaggaa
    29341 aaggtgccaa tgtaatagtt gcaatatgtc atattggtac aaatagttta agtaagccaa
    29401 atagtataga tatagcaaat gaggttcaag gaattgattt gattattgat ggacacagcc
    29461 acactaagtt tgaaaatggt aaacaagtgg gtgatacatt gattgtaagt gcaggacaat
    29521 atttagaaaa tattggcgag ataaaactaa ctttggatac taatgatgta gaaaatataa
    29581 aaatagaaaa taaatcagtt agattaattg gaaaagaaga agcattaaag tataagcttg
    29641 actacgttgt aagtaaaaag gttgatgaaa taaaagaaca acaagaaaaa atattagata
    29701 aagttatagg tgcaactaca aatactctag atggttcata tgaaaatgta aggacaaaag
    29761 aaactaattt gggtaattta ataagtgaca ttttactaga taaaactaag gctgatattt
    29821 ctttatttaa tggagggaat attcgagata cgatagaaaa aggcaatata acaagaagag
    29881 atattgtaga tgtatttcct tttagcaata ctatagttac caaagaactt acaggagcac
    29941 agattaaaga tgtattggag catggagtaa aactttatcc agaaaaaagt tcagcctttt
    30001 tgcaagtggg aggaatttca tactacttta atcctaaaca aaaagaaggc gaaagaataa
    30061 caagtattca aaaagaagga aagccattag atttaaataa aaagtatgta gttgcaacga
    30121 atgattatat agcctcaggt ggagatgaat ttccttgttt ttcaaaagag ccaatactaa
    30181 aggaatttgg aaatttagag agtgcagtca ttgaatatat agagtacaaa aaagaaatat
    30241 caaaaaatgt agatggaaga attggtatta aatctaaaga tgagttaata agcaagaatc
    30301 atgagagtga tttgatatta agtgaaaatg aaaaaaatat caatgataat gaagagaatc
    30361 tatctaataa tataaaaagc tctgatagtg acaaaaataa aagcttagat aaaacaagtg
    30421 ctagagaaag ttctaatcaa ggaatatcta aaagagaagc taaagaaaaa tctcctaaaa
    30481 caggagattt aggtttttca aatagtataa ttatatttat agtttcaagt acattgatat
    30541 gtttattgaa ttttaatcaa aaagagttaa aggataaaaa gtcaaaataa aaattaatga
    30601 gcaaaattag tagatagtaa tttaatttta gataatagta aacagcaaag gaaattagtt
    30661 atataaatac taatttcctt tgttttatgc tttaacatga ttatttttaa ataaaattgt
    30721 attttatgaa aaataattac actaaatggc atagtattat ggggattttt agtttttatt
    30781 caagtaaatg aaatcatatt aacaacttct gatatattta caaattgata aaaaaatgat
    30841 tttattagta tgatataatt tagctagtat atatgatgat ggaggatata gggatgaata
    30901 atatattact tttggaagat gacaaatctt taaatagagg aattagtttt aaattaaaaa
    30961 aagaaggata caatgttttt agtgcatttg gtatagaaga agcaaaaaat attttcgcaa
    31021 aagaagagat atgcttaatt atttccgata taggtctacc tgatggtagt ggttttgact
    31081 tttgtgagga gattagaaag aaaagtgatg tttacataat aatgttgaca gctcttgatg
    31141 aagaggtgga tattgtcaca ggatatgatt taggtgcaga tgattatatc acaaagcctt
    31201 ttagcttgat ggtattaata tcaaaagtga atgcgcttat gaaaagagta aatacagtaa
    31261 aaaattatac tctattagtt tgtgatgatt tattctttta ttatatagaa aataaattaa
    31321 ttataagaac agatgataag gaagaagaga taattttaag taagacagag acaaaactat
    31381 taaaatattt gatggaaaat tctatgcaga cattgactaa agaacaactg ttagaatctt
    31441 tatgggatag tagtggtaat tttgtagatg ataatacgat tgcagtaaat ataagaagac
    31501 ttagacaaaa ggttgaaaaa aatccatctg aacctaaata tataaaaaca gtaagagggg
    31561 ttggatatat gtggggagaa aggagtataa aaaaatgcta aaaaatatga acctcaaaga
    31621 tggtttaagt gtgaaagatg attatataat gagaagagtt attgtatatt ctgttttatc
    31681 tgtactaata gtaacccttg tatttatact ttttgaatat agcagattac ataaattgta
    31741 tgaacatcaa ataaaaaata ctcaaaatat tgctggaata ttgattgaaa aatatcctaa
    31801 tgatgaaata gatatagtaa attctattta taattccgat tatagtaagg tgtctactgg
    31861 agaaaaggca tttaagaaat ttggctatgg attggaaaat aaaatgtcaa atgataaaaa
    31921 ttttagttta tacttaaaat ctttttttaa ggaatcattt tttatttttt taatgatgtt
    31981 tatagtagtt ataggtataa tatattattt tataagatac ataaataaaa gattgagtaa
    32041 aatttatttt atagtagata agatggcaca agaaaactac ttgaaggaca ctactgagtc
    32101 agaagaaact ggttatctag tagaatataa tgagtatttt aaagaaggta catttagtaa
    32161 gataaataac tgtctatatg agcttaatag aagtttaaag ataaagttta ttaaattaga
    32221 aaaagaaaaa gaaagtgtaa aatcattagt aacagatatt tctcatcaat taaaaactcc
    32281 tttagcatcc ttaaaattat acaatacatt acttatagaa gaaaaattag aagaagatga
    32341 agccaacgag ttcttattaa ccaataaggc ttctataaat aaattagaaa atttaataaa
    32401 ttctttagtg aacatatcaa ggttagaaat tagcatgata aacataaaaa aagaagataa
    32461 tgatataaaa aatactattc taaatgcagt aaaaagtgtt acccctaagg ctaagagcaa
    32521 aagtataaca ttaaatttaa atgaatttaa cagtagaatt ataccacatg ataaaaagtg
    32581 gactgaggag agtattttta atgtattaga taatgctgta aagtacacac aggtaaatgg
    32641 agaaataaat atatctgtag aagaaactgc taatttcttt aaaattataa tagaggataa
    32701 tggcataggg attgaaaaaa atgagtttaa taatatattt aaacgttttt atagaggttc
    32761 tgctgatgaa attgaatctg tagaaggtag tggggtagga ttgtatttaa gtagaaagat
    32821 tttagaagaa caaggtggaa atattatagt ttcttcaaaa gtagggatag ggagtaagtt
    32881 ttctttgttt cttacaacta tgtaatatta aatgaaagga aaatgtaagc ctctacattt
    32941 attatataag tataaacagc tccagaaata aaaaattaat aaaatatggg gtaatataac
    33001 ttagaatgag gggataattt tatgaaaata ctatatactg aaaatttatc aaagcattat
    33061 ggaaaaggag aaaacttagt aagagctttg gacaatgtta acttagaaat aaatgaaggt
    33121 gaatttgttg caataatagg aaaatcaggt tctggaaaaa gtacactttt acatatgatt
    33181 ggaggtcttg atatacctac atctgggaag gtgtatatag ataataaaaa tatatttaca
    33241 ttaaaagaag aagaactagc tgtgtttaga agaagaaaaa tagggtttat atttcaaagc
    33301 tataatttaa ttccatctct taatgtatgg gaaaatgtag tgttgccaat cggtctagat
    33361 ggtagagaag tagatgaatc ttttataaaa gaacttttga aatcattagg acttgaaaat
    33421 aaacatgacg ttttaccaaa tacattatca ggtggtcaac aacaaagggt ggcaatagca
    33481 agagcattag ctacaagacc agctataata cttgctgatg aaccaactgg aaacctagat
    33541 tctaaaacat ctgatgaggt tatgagtata ttaaaatcta tgtctaagaa gtacagtcaa
    33601 actctagtta tgataactca tgatgacagt atagcccaaa tggctgatag agttatattc
    33661 atagaagatg gcagggtgtc aaaggttggt gataaaaatg attaatacta ctaaaatagc
    33721 aaaaagtaat ttaaaacaaa ataaatcaaa aagtattcta ataataatca ctataatact
    33781 ttctacttta atgctttctt ctattggaat ttatattgtt gatgcaggag catatcaaaa
    33841 agaaaatact ataaagtatt caggtaatta tcaaggtata ttagcaaatg tagatgaaaa
    33901 acaggctgat atattgagta atcatgcaga tgttgaatta actggtgaaa tgaatggagt
    33961 aggtgttgaa aaactggaag atgattcaaa tatttctcta gcatacatga atgaagatgc
    34021 tttgaaatta aatagttttg aacttatcaa aggaaaattg ccaacaaaag agaatgaaat
    34081 tgtgttagat agtggagctt taaaggcact tggttataaa aataaagact taggtgaaaa
    34141 gataaaaata tcttataatg actataaaaa tgataaaaaa attgaaaaag agttcgttat
    34201 aagtggaatc ttaaaaacta gcgaaatatc tgaagcaggt aaatattatt atgctattat
    34261 atcagaatta tatatgagaa atactagaga tatgtcacaa gaagatttta atatttatgt
    34321 aaaatttaat gataaaagta atttatcaat agagcaagca aaagaaaaat tagataaaat
    34381 tgctaatgat ataggacttg atactattaa tactgctgta aatgaaaatt atataaatgc
    34441 tttaaaacca gatatggaaa cgattatggg tggaggtttt gtaggattag taattgtatt
    34501 atctagtatt ttagtaatat acaatatatt ttatatttca atagttacaa aagttcaaga
    34561 atttggaaaa cttagagcaa ttggtgcaac taagaaacaa ataaaaaata tagtgtttaa
    34621 ggaagggttt atattagccg gaatagcaat accaatagga ataattttag gctatgtact
    34681 tgcaaatatt ataataaaat catttatgga tatagatgta aaatcatcac gattaccagt
    34741 tatattatcg gttgtggtaa taagctttat atctgttgtt ttatcacttt taaaaccaat
    34801 gaaagtagca tcaaaagtat ccattgttga cgcagtaaga tatacaggaa ataaaataag
    34861 taataagagt aagagaaaag gatataaaaa tataaatcta aagagattat cacatgccaa
    34921 tttagaaaga aataaaaaac gtacttacat gacattggca tcacttatac ttagtggaac
    34981 tatatttata acagtatcaa ctgctttaga aagttttgat gctgagaaaa tggcaagaga
    35041 acactttcct tatgatatag aagttagact atctggttat gaaatgaaca gtgataaaaa
    35101 tcctaaaaat aatttgaata ttttacaaat ggataatcct ctaagtaaag atttttttaa
    35161 tcaaataaag aacatggaag gaattaaaag aatagaatct gcaagaagtg taaaaattgg
    35221 tatggaggac tatgatgttg aatttaagta tgacctttta caaagtataa atgaaaatga
    35281 tgtaaaatca ttaaacaaga atctaataga tggaaaaata aatcttgaaa gactgcaaac
    35341 tggagatgaa atagtaatta ctcatgttga tacagcaaaa gaaatgggag taaaagcagg
    35401 agataaaata agattaactt tatatgatgg agataaaaag ataaaaaaag aatttaaagt
    35461 tcaagcaata gctatggggg ttccaagttt tggtataggg aaggatttta ttgatagaac
    35521 tttaaaatac gattcaacta gtagcttggg aatatataca gaagaaggaa agtatcaaga
    35581 aatcaaagat agtatcaaga agattgctaa aaataatgga tttttagaga ctgattttat
    35641 agatagtaga attgagtcaa ataaggctgt tatttcattt ataaagataa tgggatacac
    35701 gctaacaggc ataataggtg tgattggatt tatgaatctt gtcaacacaa tgataactag
    35761 catagttact agaaaaaaag aacttggtat gcttcaagct attggtctta ctaataaaca
    35821 attagtgaaa atgcttaatt cagaggcaat gtattacact tctggaatga tgataggaag
    35881 tattttattt ggaggtatat tagggtatat tgctgttata tttctaaaaa agactggatt
    35941 atcttatgca acatattctt tgccaatagt accaatcttg ttgatgattg tgtgtattct
    36001 tatagctcaa tttataacaa cttatttgat aggacgaagt tttaataaag aatctcttat
    36061 tgatagagta agatacagtg aataaaatgc aaatatttgt ggttagttta actagcaaaa
    36121 agcatataaa aaatatagtt aaagagattc ataattaaat aggttaaagc atagtacaga
    36181 gcaaacaatt taaacggatg tttgctctgt attttattat gtaatcaata atatatctaa
    36241 tatactgata ttattcatgt tagaaaatgt atcggtacaa ttctaaaaaa gtataaaatt
    36301 gtaccatata aaatgaaaat tttgtataat aatcgtatag aaaataaata ggagctgata
    36361 tatatgaata agaagattaa ttatgcacca ggaccaactg aaactaggga aaatgtaaga
    36421 ttagcaagag cagaaaaaac aacaaatcca gatatagata ttgattttgt tgaattttat
    36481 aaaaagacat gcgagaagtt tggcaatata gttggaacaa aaaacgatgt ttacatattg
    36541 agtggtgaag gaatattagg gcttgaagca gcatgtgcat cacttaccga aaaaggagat
    36601 agagtacttg taattgacaa tggtatatat ggagaaggtt ttaaagattt tgtaacaatg
    36661 tatggtgggg agtatgtgct tttttcaagt gaatatacta aaagtataga tattgatgaa
    36721 ttgaaagcat ttttagatga ggatagtaat tttaaatatg caacagtagt gcattgtgat
    36781 actccaactg gcgtattaaa tgatgtaagc aaaatatgtc cattacttaa agaatatgga
    36841 atattaactg tagttgattc tgtagcaggt atggtaggag aaagattaag tgtggatgaa
    36901 tctaaaatag atataatatt aggtggttca caaaaagcta tttctgcacc agcaggactt
    36961 actatagttg gaataagtca agatgcaaaa aattgtataa aaaatagaaa aactgatgta
    37021 ataggttttt attgtaattt aaatatatgg gaaggctatt atgaaaaaaa atacttccct
    37081 tatacaatgc caataagtga cataatgggg cttgataaag cacttgataa tatattagaa
    37141 gaaggaatag aaaatgtatt agatagacat gaaaagatag cttatagtgt tagaaaatct
    37201 attgaggaat atggtctaga actattttta gaagaaggat attctaatac agtcacagct
    37261 ataaaaattc ctgaaagtat aggagcttta aaacttactg attatatgct taaaaattat
    37321 aatacacttg ttgcaacatc actaaatcaa tatatggata ctattttaag aataggtcat
    37381 atgggagaga atgcaaatct aaataaaata gagcatgtac taaatgtctt ggataaaagt
    37441 ttaagtgcat taggattcaa aggaaatgaa aatttgttga atttatttaa taagtattat
    37501 ttttaataga tagggggata tagtatggaa gttacagcta agcaaaaatt tacaacgaaa
    37561 gacatggtgg aaacctcact attaatagca ttagtattta ttgcaactaa atttataaat
    37621 ataagattac caatatctat aaatggtggg cttgtgcatt taggaacagc aatgttgttc
    37681 atatcagcaa tagtatttgg aagtaaaaaa ggtgctttat caggagctat tggtatgtca
    37741 ctttttgatt taatatctgg gtggacttta tgggcaccgt ttacctttat agttagagga
    37801 gttatgggtt atttacttgg aaagattgca tgggcaaatg gtaataatgg gaataatttt
    37861 ttaatcaatg taataggaat atgtgtctca tcaatttgga tgttatttgg atattatata
    37921 acagaagtta tactttatgg taattttata gtacctctta cttcaatacc aggtaactta
    37981 atgcaagtat tgataggtct tataatagcg cttcctattt ctaaggtatt gaaaaaatgt
    38041 ataaaataaa tataaagtga actaaaattt atgatagcat aaattatact gtataatatt
    38101 aagatggagt acataattaa aaaattttag tatagaggtt agttcacaat gttatcagtt
    38161 acaagatatt caatcaaaaa tgttcgttta aagccgtggg taaagtttat ttggtatttt
    38221 gaaacaaaat caaatatact gttaaataat aagttacttc ctacagacag tatagatatt
    38281 attcttaatc tttctgatgt tatggaatat aaaattgaaa atcaagacta tactgctagt
    38341 aatatgcatt ttaatggaat aagggataaa catggattta ttattcaaca tggaaatata
    38401 cgtgttatag ggatttcttt ttatccattt ggtctctatc catttttaaa gataccaatt
    38461 tcagagttta acagacaaat tgttgactta gaagcagtat cagaactatt tgccaaaaaa
    38521 ttggaagagt cattaaatcc aacacaatca gtagaaaaaa ttgttttata tttagaagaa
    38581 atgttattat ccatattaga agaagattta atttcaaata aatctgtaaa gcttctaaat
    38641 tcatttatat atgataatag atatagcaat ataaaagcat tttgtgataa tacaaatata
    38701 aatattaaaa cattggaaag aatctgttta aaatatacag ggtatacacc taagatttta
    38761 aagagaattt acagatttaa aatggcaagt agtcaactta tttataatta taaagataat
    38821 gaactttttg attttattta tgaaaatgag tactatgacc aagcacactt tataaaagaa
    38881 tttaaaaaat tttcagggac gtcaccaatt aaatttattg gtgagaataa gacgattaaa
    38941 gaaaatataa agtacaacta tttataatta tactgtcgat tttttacaat acctccaatt
    39001 tattttttga tatgatatag gaaaataaat tggaggtttt acatatgaaa attattacag
    39061 aaatagttga gtttaatgtg gaagaaaatt tatcaaaaga agagtttata gaaattgtaa
    39121 atgacttaga attaaaattt cattctattc aatctggttt tattgatact gagcttttat
    39181 atgatgaaaa gtctcaaaag tggattatga tacaacattg ggaatctata gaagacctca
    39241 agagtgcttc tagtaaaatg tttaaagatt cttcaactga gaaatttaga aaagctttaa
    39301 agaatcaaac tgttaagatg aatataatac cacaaattaa aagttggaaa ttatagaact
    39361 gaatgtaaaa gatagttaaa tagtatcaaa ctaaattagc caaataacat tttgtattta
    39421 aattgttatt tggcttttag tgtttacttt aatatgagtg ttatatacta gaaaaaccaa
    39481 caaactgtta gagtgtggat tataataatg tcatatttgg gagctaaaag gcttaatact
    39541 gatttgtcaa tatgtctttt tagcatgttg aacaggtata ttgccatgct ttcattattt
    39601 tatttttttg ccttatactg gactacattt gcagtttcct aatatatttg gctcatattt
    39661 aaatgccatt atctaaaagt actattgctg tacgagaggc aataggcatt ttagaagaag
    39721 gaggagttga gctaaagtat acatcataat ctcttaagtt ttcttttttt gtgtttcctc
    39781 caaactctac catatcagta tttaatatcg ttttgtagtt tgtattttga aactttgaaa
    39841 tatcaactga ttgtattaga ttagggtgga aattaaatat aaataaatat ttgcccttac
    39901 tgtacaccaa aatcttttta tcattatcca tatgtataag ttcatgacta ttttggataa
    39961 aaatatcact gtattttgta agttcgagca tagatttatc aaaatttaat aattgtttat
    40021 actttaagtt gttatcttct gaaaggctcc attgtcttct ggcatactta tagctccaat
    40081 tgttgccttc tcgtggaaaa tcaatccact caggatgtcc aaattcattt cccataaaat
    40141 ttagatatcc ttcacctgct agagaaaaag ttattaattt aattaattta ataagagata
    40201 ttgctctatt gataacatgg ttatttgagt ttatttccat attccagtac atttccttgt
    40261 cagctagcca aaaaataatt gttttatcgc caactaatgc ttggtcatgg gattcacaat
    40321 atcctatatt tttttctcca ggtcgtctag tagtaagttc ataccacatt tttcccaaat
    40381 cccagtcttc atcagataag ttagagatag tttttatcca aaaatcaggt actcccattg
    40441 cgagtctata gtcaaatcca attccgccgt cttttatagg gatacacata ccaggcattc
    40501 cactcatatc ttctgcaata cttatcgaat taggtttaat ttcttttatt aattcatttg
    40561 caaattggag atatgttata gcttcaatat ctgtattcat actaaaatat ttttcataac
    40621 tatcaaatga aactccaaga ccatggttat gatataacat tgaagtcaca ccatcaaacc
    40681 taaagccatc aaaatggtac tcatttaacc aaaattttat atttgaaagc aaaaaatgta
    40741 ttacttcagg tttaccatag ttaaaaagtt ttgtacccca agcaggatga tttccctttg
    40801 aacctgagtg gaaaaattga tgttcacttc catcaaactc atttattcct tctaaagtat
    40861 tctttacagc atgagaatga actaaatcca ataaaacagc aatccccatt gaatgagcag
    40921 tgtttatgag gttttttaag tcttcaggag taccaaacct agatgagatt gcataaaagt
    40981 ttgaaacttg gtatccaaaa gatgcataat atggatgttc cataatagcc ataagctgaa
    41041 tggtattgta tccagctttt tttatcttag gaagtatttt ttcagtaaat tcattataag
    41101 ttccaataga ttcgctttca gtagacatac ctatatgaca ttcatagatt agtggagaag
    41161 ttatgttttt taagtcaaaa ttattgtcag tccagataaa tggagttttt ggttgccata
    41221 tttgtccatt aaatccacca aaatcttttt gaattactct ttttatatat aatggtatac
    41281 ggtcaaatgt ttttccattt gcagtaactt gtacctttac ctctgatttg tgaggtaagc
    41341 tattttgacc aggaataaat atttcccaat taccagaccc aatttttctt agaggatgag
    41401 attttctatt ccaattatta aagtcaccaa ttagtgacaa actatctgca tttggagccc
    41461 attccctata gaagaatcca tcatttgtct gatgaaatcc atagtaaaga tgagcatttg
    41521 caaaagaact aaaatcttta tagtttttca atgtttttga tttcatatcc tcataatgtt
    41581 tcattcgctt ttttatatca gattcaaatg gttgtaggta tacatcaata tctaaaattt
    41641 taaatctttt ttgacttttc attgtatttc tcctccataa taaatattac atttaaaaaa
    41701 taatatttat ctcatactat cttctctgta taattgatat atattatata atcctaataa
    41761 aaagcttaag ccaccaatga ttaatttcat aatttacctc cctagtattt atacttatat
    41821 atcgtattca tcaaaattta aaagtttgtt taaaactctt ttaataatat cataatcaaa
    41881 gcctttatag gaaagatgtt gagaaatttt ttgatatatt ttctttttat cttctttctt
    41941 tactctttca tacctttttt ttgctagata catagcattt tcaaattcag tgtccttgtc
    42001 taattcagat actgcttcat tgattgtact tctattgata cctttattat ataaattctg
    42061 cttaattctg tttttgccac atttatttag gttaacattt gtgttaacaa ttttttgagc
    42121 taatacactg tcatttacga gattataact tttaagaaaa tctatgaccc tctcaattat
    42181 attttcatca aattctgatg atagtttttc ttttaatttt ttttcagatt ggtcagcatg
    42241 agataaaata tttaatgctt tatttttagc ttttatatac atttcatcat ctaaaatagg
    42301 ttttaattct tcttcattta tttcattccc tttttttaaa ttaaatgtat aaacaagttc
    42361 tttaaatata gcaataaaaa atttatcatc tacataaata ttaactctat catcatttct
    42421 tttttgttgt tctatttttg taattatacc cataagtcct ccttttttat atgtaattat
    42481 attaacaaaa gcaactaata aaatttaaca aaaaacttat atttgtatgt tatattttat
    42541 caaaattaag acaaaatagt aaaaagttat ttttattaaa aagtaaagca gaatcatgtt
    42601 aaataattat tttttaaagt gttttttagc atataaatat aattatatac ccaaaaaaac
    42661 aaattataag ctttaagaaa taaaaaataa tggtacaata gtattataac attaaaagga
    42721 gacaaaatat gagaagtgaa aatctagtta agatggcaga gttgaaaaat actgaaaaac
    42781 tagagaaatt taatcgccat aaaggcaaaa tcaaaatagg tatattggga ggtacttttg
    42841 accctataca ctatgctcat ttagcaacag cagaatttat tagagacaag tatgacattg
    42901 acaaaataat ctttatacca tcaggaaatc caccacataa attatgtatc actacagata
    42961 agtatgatag atataatatg acacttctag caactgaaag caacgaagat tttttagttt
    43021 caaaagtaga aatcgaaaga aagaaaagga cttatacaat agatacatta aaatacttaa
    43081 agaaaaaata caaaaatgca gacatttatt ttataacagg tgcagatgca atttgtagtg
    43141 ttgaagagtg gaaagatgta aagaaaaact ttgagttagc tacttttata gccgcaacta
    43201 gaccaggaat tagtttgtta aggtcacaag agactataga aaaactaact aagaagtata
    43261 atgctgacat tataacagtt tatgttccat cactggatat atcgtccaca tatataaggg
    43321 aacagctaaa tgaaggcaag tcaatacgtt acttagtacc cgaaaatgta gaaaattatt
    43381 tatatgaaaa taaactatat caatatggag atgattaaat gaacttagaa aatattaacc
    43441 aaagactaaa tcaaatgcta ccagtgggga ggcttagcca ttcaagaaat gttgcaaaat
    43501 gtgctgaaaa attatgtgag atttatggat gtgacaaaga aaaagcttac ttagcaggaa
    43561 tgattcatga ttgtgcaaag tatttaagtg acaaggaaat agaggattat gtaaataagt
    43621 atgaaatata tttagaccca atagaggatg gaaatcgttc cttgtctcat agtgtaattg
    43681 gggcgtacat atgcgagtat gaatttgaag tagaagatga agatattata aatgcaatca
    43741 aatatcatac aacagggaga gaggacatgt ctcttttaga aaaaataatt tacatagctg
    43801 atttaattga agaaggaaga aaatttccag ttgtagatac attaagagaa ttagcatatg
    43861 gagggaagct tgatgaagca cttttaactt cttttaataa tactttaatg tttgtcatca
    43921 ataaaaaaga agagatacat ccaagaacag ttatggcaag aaactatcta attaaagaaa
    43981 agttattata aaaaagctat ataaaggcaa acatattaat aaatttaaat ttgactatgt
    44041 tacaaaatcg tattaatatg ttacaataac taagtgtatt ttaattagga aagtgaggaa
    44101 tttttatatg acagtggaac aaatgacaaa aatagcatat gatgccatag aagataaact
    44161 gggtcaagat acagttataa taaatatagg aaaagtttct agtttgtgtg attattttat
    44221 tattactaca gcatcttctc agagacaggt aaaagctatt gctgacaatg tggaagatga
    44281 attagcaaaa ctaggattag agccaagagg taaagaagga caaggaactc aaacttgggt
    44341 actccttgat tatggagaca taatggttca tgtatttaat gaggaaaata gagggtttta
    44401 taatttagaa aaattatgga aagatgcacc ttatatagat attgacacat tagcataaac
    44461 atgataatat atgttattat aattagaaaa tttcaaaaat tatattaaat tgaatagact
    44521 agagcagtaa aagattatat tttttcagag agttagtgga aggtgagaac taatattata
    44581 taactttgaa cttactagat taaaatctat tctccatggc tggattaaaa gctatctaag
    44641 agagtctata tatgtagtag gctaattagg gtggtaccgc gaagatttat cctcgtccct
    44701 aaacgtaagt ttagtgacga ggatttttta ttttcaaaga attatttgga aattataagt
    44761 aaataatact aaataaggta gttatacaca attaaaaata ggaggcaaaa tatgagcgta
    44821 tataatttta aagaagtaga atcgaaatgg caaaaaattt ggaaagataa taatcagtat
    44881 aaaatggata ctgcacaaac tgaaaaacct aattattaca cattagaaat gttcccttat
    44941 ccatctggaa aaatacacat gggacatgtt agaaattatt ctataggtga tgttgtcgca
    45001 agattcaaaa aaatggaagg atataatgta cttcatccaa tgggatggga ttcttttgga
    45061 ttaccagctg aaaatgcagc tataaaacat ggaatacatc cgcataaatg gacaatggaa
    45121 aatatagaag aaatgaaaga gcaattaaat ttattaggta ttagttatga ttgggataaa
    45181 gaagttgcaa cttcaactcc agaatactat agatttacac aagaaatatt tttgaagttt
    45241 ttagagcatg ggcttgcata taagaaaaaa tcatatgtta actggtgtcc ttcttgtgag
    45301 actgttcttg caaatgagca agttgttcaa ggagcatgtg agagatgtaa agcaacagta
    45361 ttaaagaaag atttagaaca atggtatttt aagactactg aatttgcaga agaattactt
    45421 aatgacttag atacattaga tggatggcca gaaaaagtta aaacaatgca aaaaaattgg
    45481 ataggtaaaa gtacaggagc agatttagtt tttgatatag atggaactga taaatctatg
    45541 acagtattta caactagacc agacacaact tatggagtta cttatatggt acttgctcca
    45601 gagcatgaat tagttaaaga attggttgca gggactgaat atgaagcaga tgttgaagct
    45661 tttgttcaaa aaatgcatac tatgacagaa atagaaagaa cagcagctga tgtagaaaaa
    45721 gaaggaatgt ttataggtag atatgttata aatcctttaa atggcaagaa agttcctcta
    45781 tggatagcta actatgtatt agttgagtat ggaacgggtg ctataatggc agttccagca
    45841 catgatgaaa gagatagaga ttttgctgaa aaatataatt tagacataat tgatgtaata
    45901 acagaagata acaaaatgat aaattcagaa gaatttaatg gattagatgc ttcagaagga
    45961 tttgaaggaa taatcgataa gttagaaaaa gaaggtagag gaaagagaac aattaattat
    46021 agacttagag actggttagt ttcaagacaa agatactggg gttgtcctat acctgtggtt
    46081 tattgtgatg aatgtggaat agttccagtt aaaaaggaag atttaccagt tcttttacca
    46141 acagatgttg aatttactgg aaagggagaa tctccactta cgacttcaaa gcaatttatg
    46201 tcaacaactt gtcctcactg tggaaaacca gctagaaggg aagttgatac tatggataca
    46261 ttcgttgatt cttcttggta tttcttaaga tatgtggata gcaataatga aaatgaacca
    46321 tttagtaagg aattagttaa tagatggcat ccagtagacc aatatatagg tggagtagaa
    46381 catgctataa tgcatttgct ttatgcaaga tggtttgtaa aggcatttaa gagtatggga
    46441 atggtagact tcaatgagcc atttaaaaac ttacttactc aaggaatggt acttatggat
    46501 ggttctaaaa tgagtaagtc taaagggaat acagtatctc ctatggatat aatagatgag
    46561 tatggagcag atactgcaag acttttcgta ttatttgcag caccaccaga aagagattta
    46621 gactggtcag agcaaggtgt tgatggatgc tttagattct taaatagggt ttatagattg
    46681 gttgacgagt tagcagatgt ggttaaaaag gatgtagagt ttggagaatt aaattcccaa
    46741 gataaggata tgagatatac tatacactct acacttaaaa aagttactgc tgatttaagt
    46801 gaaaaattcg gatttaatac tgctatatca gctcttatgg aattaataaa tgatatgtat
    46861 aaatataaag agttagataa tataaacgaa gcagttataa aagaaggtgt acaaactata
    46921 gtaactataa ttgcaccatt tgcccctcat ttaggtgaag aactatggac tatgataggt
    46981 aaagaaggaa gtgtatttga tatagactgg cctaaatatg acgaaaaagc tttagtaaaa
    47041 gatgaaatag aagttgttgt acaagttaat ggaaaagtta gaggaaaatt aactgttaac
    47101 tcaaatatat ctaaagatga gatggaaaag gtagctttag aagatgaaaa aataaaagga
    47161 ttagttgaag gtaaaactat agttaaagtt gtagctgtac ctaaaaaatt agtaaatata
    47221 gttgttaaat aactcaaaaa tatgaacaaa aatataaatt tataaaataa atgaggctgt
    47281 ctcaaaatag agataagcct tttttcattg ttgaaattac aaaaatagat ttgattttat
    47341 acaaaaaaat gattaaagaa ctaaaaagtt cattcttata cactctaatt gttgttttaa
    47401 atattattat aattaatgtt aaatcgtgtt aatgtattaa gtggtatgta aattattcag
    47461 tttctaaagt gttgttcatc aaggaactgc tctaagctta aacgaaaaaa atataattat
    47521 tgtattttta aaattttttt tatataatga aaacaggcaa aaaaggtgcg tatctatgct
    47581 ttatcttaaa cacccagaca acgagattca gattcatata ataactacca tgtttctaaa
    47641 aaggaacttg caaaaaagat aggcgtttca acttcccagt tgattaaaat tatcaccagg
    47701 aaaacaagga tggtcagcag tagtattcta atgggtgttg ctgatatatc caagttggga
    47761 ttgtttgagg atgttatcaa atgacttgtg ataggtgcag tagatgtgga gattcctgat
    47821 acggatttat tctcagggga tgtttgcttc aggagatatg gagcgtaacc agtttattga
    47881 tatggtaacc atttttttgt ctaatttgat gaaagaatcc caagaatacc atacagaagt
    47941 aagacaggaa ttaactggtg gtataaactg ataaaggcaa atttaaaaat tttgatagga
    48001 tgattttaag atttatcttc tattttgttt tttagaaata attgaaatgt tatgaggggg
    48061 tgtgtacaaa tggagactgt atcaaataat caatcaagtg tagaaattca actcagtctg
    48121 tttgaagcta tcaaagattt attgttaatt aatcctattt tcttgttggg aattatcttg
    48181 attggtattt tcttagttgt aatattcaag aaaaatagtg atattccaaa ggtaaaaaca
    48241 tctattttat cactggcaat gtattactac ttatgtttaa cactatcgca tattgttggt
    48301 atccctacat tcagtgaata tataagactg tcacagttag gggaaacgtt ctttaatcca
    48361 aacataaatc ttattccttt tagtgatgga tttagtttga gttttatttt gaatatttta
    48421 ctttttgttc cattaggttt tttatgtccg cttatcagca aaacctttga acggttgaga
    48481 aatacattct tgattggttt tggattatct ctctttatcg aaactattca gctttttacg
    48541 ttacacagag caaccgatat agacgactta ctcacgaatg taattggaac aataataggc
    48601 tatttctgct tcaaactgat tgctaaattg cgaattgtaa aactacattc agatgatgac
    48661 tctatggaac aggattacac agtatgtatt ccgattgcca ttataatagt tgcccttata
    48721 ttaggatttt ttagttaagt tccaaatagc taatttggga atccagacaa tataacagat
    48781 agtatgttac cttttacagg agcatactgt ctgttatgtt gtcaacatct cattttatgg
    48841 tttgtgtgta ttttcttgta aactgaacta aataattaaa tagaagttat tagaattagc
    48901 aatagattcc tttttcaaag aaatctttga tttcatcaag gttatcagtt tttccaagtg
    48961 ctaagataag ttttattcta gctttttgac ctggcaagtc cccaccaaat atacaaccaa
    49021 gattttttaa atctctacca gaaccaaagt aaccataact atcgaatact ctacctgaat
    49081 gacatctaga aactataact acaggaagtc ctttttctct agcatattca actccagaaa
    49141 gcatttgagg aggaatatta cctataccca ttgcctcaat aactatacct ttataaccac
    49201 tatcaacagc aaatcttata aagtcagcat tttctcctac atatgcttta aataaggcaa
    49261 ctttagattc taccttatca gtatctataa ttgttctatt tacaatatct cttgtaagga
    49321 caagttcgtt gcagtcaatt attcctaatg gaccactagt tagagattta aatgtattta
    49381 gagaaagagt atttgtttta gtagcttcag aagctaataa tacttcattg tttaaaacta
    49441 caaggactcc ttttcccata gcatctttgg atactgcagt acaaactgat gcagataaat
    49501 tacttgaacc atcatatcca agttcagaac tacttctcat agcacctgtg actattacag
    49561 gtttgatgtt gtcaattgta aggtctagaa aataagctgt ttcctctaaa ctatctgtac
    49621 catgtgttat tacaacacct gtaatatctt ttcttgctaa taaatcattt acataatttt
    49681 tcaattccat cattctataa ggtgttatgt gaggtcctgg aatttcatca aaattaaaaa
    49741 cttcaacatc tgcaacttta tcaatgttgg taaccattga tagtatttgt tcacctgata
    49801 aagttggtat agctgctccg actttatcat ctactgtcat agatatagtt ccaccagtaa
    49861 aaactatggc aacttttttc ttaatactca tacgattctc tgcctttcat aaataaaatt
    49921 tataattccg ataggattat atcaaaaaaa gtagttaagg tctacataaa ctcttttatt
    49981 catataattt agatatttca gtgtaatata attatttctt aattttttgc cattcaacga
    50041 tataaccatt taatatctct cttatggctt ttcctatctt agtataagct tcatcatata
    50101 gatttgctag agatattcta attgaccatt cagggccata gaatccattt ccactaagta
    50161 aaactactga atagtcatta gctaatttat aaagaacatc tactggagat gcagttttac
    50221 ttataaattt aaataagtct tctccgtagt ttaatttagc ccattcttca atatcaaatt
    50281 gagtgtaata tgcagcattg tttttgtttt cattaattgg aagctctaaa gcttcaaata
    50341 atagtttttg acgtctatgg cagatactca tattgagttt tttgtaggca tctactttgt
    50401 caatcaatgc aaaagcagag aaaaacgcca tttgtacttg ctgtggagta gaaagaccag
    50461 cagtatggtt gagagcaaca agtctgctat cagcaacaac tctttccata aatgaaagac
    50521 tagaagggtt aagactcata tcactgtaac gcttatctac tgattttttt aattctccag
    50581 ttaaatcatt tattttctta tcaaaaacat ttttcttatg aagggcaaat gtaccaagtc
    50641 tccatcctgt aactccaaaa tattttgaat aagaatatac tccaacagtg ttgtaaggta
    50701 gttttgacat taaggatgaa aaatcttcta caaaagttcc atatacatca tctgatatta
    50761 tcattaaatc tttattataa ttttcaatta catctattag attattacaa gatatttcat
    50821 ccatagctat agaagcagga ttattaggat taacaacgaa taaagcttta atagatttgt
    50881 cacgaagttt ctctaattct ttttttgtat attgccatgt atgagcacct ttttcatcaa
    50941 cttcattagc atttatattt accactttaa agtcgtaacg aggaaggtta ggtatttcaa
    51001 gataaggtgt aaatattgga gtcattaagg ctattgtatc tccttttttt agaagttcat
    51061 ttgccattaa tgaatcaaat atatagcaca tagcagctgt agcaccttca acagcaaaaa
    51121 tttctacatc accatattta cctgatatat catatttcat ttcttgaact aggtaatcgt
    51181 gtactatttt ttccatatga ggtaacattc tatctggaag tggatagtta tcaccaataa
    51241 ttccatcagc tagttcatga acaaattcat ctccatcaaa tccaagttca tttataccaa
    51301 agtttataat atctctagct aaatatgctc caggcatatc tatattttca tttataaatt
    51361 taaaaaatct ttctttaata cccttttttt gaggcattcc agccaaatga cctaaatccc
    51421 aattagaacg agtttcagta atagcgaaat gaccaaaagt aaaaaaggct tctctagcag
    51481 ttgaacaagt ccagtttgga tttccacgac ctgcatcaag taattctctg ttattttctt
    51541 ttgcagtgta ttttgcaata tctattaatt tgtccttaaa ttcaaaaggg cttatttttc
    51601 catatatgtt tttgatttct ttataagtat gatttttcat gttaaattcc tccttatgta
    51661 ataagtttca catttttata ataaaataaa caagttgcaa aaatgattat actttaatta
    51721 taataggttt atagaaaaag taaagtatga aattaaaata ataactcta
//
LOCUS       DAMJYN010000019        51664 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.019, whole genome shotgun sequence.
ACCESSION   DAMJYN010000019 DAMJYN010000000
VERSION     DAMJYN010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 51664)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51664)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51664
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.019"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            219..3767
                     /locus_tag="PC466_001229"
     CDS             219..3767
                     /locus_tag="PC466_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HDF2768622.1"
                     /translation="MMNRLKPRILGISILFIIIIILTCGAVFKFKFKLDNKLKETTHT
                     YLSEFTEHNIINLKTRLSGQFDMLESIANFIGNLNNINNEMVIALMDSDVKRSSLIRM
                     TISTLDGECYSNDGITHNVQDRDYFKKAKNGEKNISEPLKSIVNNKEIIVLSTPVYKS
                     GKIVGVLSGIYDSKKLNELLGLSAFDEKADVFVAKKNGDIVAQKTNKNRKTISCIFQL
                     FDKDNCDEDDCLKTIKENMKNDKSGYFNYNLDNEKFMLNYQPLGVNDWYVFSVVPNKI
                     VSIQSENISYDVYIFALEILLVILIFIIYIACIINNNTKIIINEKEKFKVLTDNILGG
                     VKTCLKDEYMTMTYVSQGFLELTGYSCEDLNKIFKNRFKDMIYKDDLDKFNCIILNQL
                     EKQDKIEVEYRIVRKDGSIIWILERSKSINDNKGSECIQGVLTDITELKKIQEELDSK
                     RFEIQAINDSIVGGIVITEINDDFDSIYLNEGYLNMIGYTRKQLEDELNNKLIKLIFK
                     DDRTELINSINKQLKLSDTFASEQRVEKRDGTIIWILLKGRKIIYDNGKSVLCCVIVD
                     ITSAKLLEQELKKSEERHEIILKQTQNIIIEWDIEKDKMNISPNWYNKFKYDPITENA
                     TKNIIKSVDIYHDDMDKFISLIKLTSQGSEYEECEIRLRTRDTIYAWFSIKATTLFDN
                     NGKPYKVVGSLTDIDESKREAEKLKERAEKDPLTDLYNKKASQSLIEEYITLDKKRKG
                     ALMIIDIDNFKGINDNLGHLYGDAVLSEIANDLINLFRATDIVGRIGGDEFIVFIKDI
                     SETRDIINKAEELVKTFERSFLGKGRNYKISLSVGIAKFPQDGMDYMTLFRNADMALY
                     SAKGKGKNCYTLYDKKIDKVQYITNTRNAGDSDNVEMSFKEHITNYIFDILYESSDIE
                     VAVNLILSIVGKHFNVSRMYIFENSDDNRVCKNTFEWCNEGVTSEINNLKNICYKDLG
                     NYLLNFNADGLFYCNDIENLGSDVKKVLKPQGIRSILQCKILEGNEFRGFIGFDECSY
                     NRMWTNDEVNTLTFISKTLSMFLLKMRIQSKLEESLTIQKSVMDNMDIWAYVVDRNTY
                     ELLFINKKMLESASNTHVGDLCYKAIWNNQDKPCKKCPMIYLKDGDDTYKSFMRNKKF
                     EVQANITTTTLKWFDGKDACLIFGSEVTSIEAEENT"
     gene            3952..5886
                     /locus_tag="PC466_001230"
     CDS             3952..5886
                     /locus_tag="PC466_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgiQ family radical SAM protein"
                     /protein_id="HDF2768623.1"
                     /translation="MENKFLPISKQDMIDRGWEELDFVLVTGDAYVDHHSFGTAIISR
                     VLENAGYKVGIIAQPDWRTTDDFMKLGKPRLAFLVNAGNMDSMVNHYSVSKKHREKDM
                     YSPGGKMGYRPDRATIVYCNKIREAYSDVAIVIGGIEASLRRFAHYDYWSDKVRKSML
                     IDSGADLLVYGMSEKQIVEVANALNDGYDPKYIRHIDGTCYISDTLEEIYDKYILIPS
                     YKEICEDKMKYVEAFKIQYDEQDPFRGNIIVQPHGSKYLVQNKPEKPLSREELDEVYG
                     LPYQKTYHPVYEKFGGIPAIEEVKFSIVSSRGCFGSCSFCAITFHQGRAVQSRSEKSI
                     IDEAIGITNLDDFKGYIHDVGGPTANFRRPACKKQITKGACKNRQCLSPSPCKNLDAD
                     HSEYLHLLRAVRKLPKIKKVFVRSGIRYDYVMADKNNKFLRELIEHHVSGQLKVAPEH
                     ISEEVLKYMQKPAGKTYDKFRQKFFAINEELGKKQYLIPYLMSSHPGSTLNSAIELAE
                     YLRDTHYQPEQVQDFYPTPGTLSTTMFYTGIDPLTMKPVYVPKSKRDKAMQRALLQYR
                     APRNYDLVYSALVEAGREDLIGFGHRCLIKPKNEKPYFNRNNSKKNVSKGTNKNKKTN
                     TNNRSNKNQQKSSTKKKKKH"
     gene            5992..6987
                     /locus_tag="PC466_001231"
     CDS             5992..6987
                     /locus_tag="PC466_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF2768624.1"
                     /translation="MKKYISIILLVVVTMVVLVGCSPGKDNPKNKELSVVKQVKVAVP
                     DGLPAVAIAKLANENPEIKEGYETVYSIEKTPEAISTRVMKKDADIAIVPSNMAAIAY
                     NKTSSYNIVGTVGMGSLYLVSTENIKDYSDLVGKEVGCTGKGLTPDITIKSLLLQKDI
                     NYSNIKFNYVNSASELVPLLATGKVKTGIVPEPALSALMSKNPDIKIIKSLNDSWKEV
                     SGSKDGYPQSTLIVKSEFLRDNKDFVDSFVGQLSNSIDWANKNPEELGAYSEKIKIST
                     ESKIIGKSLERANLKYIPVKDMIKDYKNYYEKLANFDDKTLGGKVPDEAIYFVEK"
     gene            6959..7744
                     /locus_tag="PC466_001232"
     CDS             6959..7744
                     /locus_tag="PC466_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HDF2768625.1"
                     /translation="MKQYTLLRNKKNKEQFIDKMEVTLSCVILLFLWQIIALKIDNDI
                     FLPTVGQVFNSIKEIMLNSSFYIDILYSMGRCFFSFLLAMIFAIILSIVSYLNRFFRN
                     LLKPINALTRSIPTMILVVLALIWFEKDSTPFIVGFTIVFPILYDNVLGAILNIDKNL
                     LEMANVYKIRFIDKVLKIYLPAIKFQIISILVSTFSLSLKVAIAGEVYSQPTYGIGTM
                     IQTEKINFNTSGIFAWIIIVLLISAILQIAQKFLARRAFLWKR"
     gene            7732..8430
                     /locus_tag="PC466_001233"
     CDS             7732..8430
                     /locus_tag="PC466_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2768626.1"
                     /translation="MEKIKLSIENINKRYDSRIIFRDFNIDFYVNEVNCILGKSGCGK
                     TTLLNIISGIIKNDTNNLNIKENLNRVGNKLEASYIFQDDRLIDWLTVEENIKIVVNK
                     YYNKTQLNKICDEYLELVGISDYKKFYPQMLSGGIRQRVNIARAFIYPSKNIIMDEPF
                     KSIDAKNTQLIMDNFRNILRKEKRTVLFVTHNIEEALFLADRIFILGDSPIRIKKILK
                     NSKELEKNEVLKLI"
     gene            8553..9026
                     /gene="ybaK"
                     /locus_tag="PC466_001234"
     CDS             8553..9026
                     /gene="ybaK"
                     /locus_tag="PC466_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HDF2768627.1"
                     /translation="MVKTNAMRILDSNKIDYKVMSYEVKSEHVDGVEVAHDIGRDVNE
                     VYKTLVTQGVSKNIYVYVIPVHENLDLKKAAKVAKEKSVEMIHVKDINKLTGYIRGGC
                     SPIGMKKLYKTFVNESAKNLDTIIVSAGKIGYQIELSPFDLQRLIKVEFVDVIKK"
     gene            9223..10062
                     /locus_tag="PC466_001235"
     CDS             9223..10062
                     /locus_tag="PC466_001235"
                     /EC_number="4.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate hydratase"
                     /protein_id="HDF2768628.1"
                     /translation="MRKIKSEQIVEQVKKLCIEASLYLGEDVLSCIKEKAKSEKSEVG
                     KNILNILVENAEIAKEKNIPICQDTGMAVFFVEIGQEVLIEGDTLTDAINEGVRQGYE
                     EGYLRKSVVSPINRVNTKDNTPAVIHYDMVKGDKIKIEFAAKGFGSENMSKMKMLKPS
                     DGLEGIKKFIIDTVSEAGPNPCPPMVIGVGIGGTVDKCAQIAKKALFRELGEFNKDEN
                     IAKLESELLTAINKLGIGPQGLGGTTTALGLNIETFPTHIAGLPVVVNINCHASRHKK
                     VVI"
     gene            10075..10623
                     /locus_tag="PC466_001236"
     CDS             10075..10623
                     /locus_tag="PC466_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S-containing hydro-lyase"
                     /protein_id="HDF2768629.1"
                     /translation="MIKITTPVNEIDIAKLNCGDTISLSGILYTARDAAHKRLIDCIN
                     KGEELPFDVYGQGIYYVGPTPTKPGEVIGAAGPTTSYRMDDLTIPLLERGLRLMIGKG
                     KRSDEVIEGMQKYGAVYLAAIGGAGAYISNSIKSCEIIAYEDLGAEAIRKIVVEDLKL
                     TVAIDSYGNNIYEQGRAIYECK"
     gene            10689..11870
                     /locus_tag="PC466_001237"
     CDS             10689..11870
                     /locus_tag="PC466_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent malic enzyme"
                     /protein_id="HDF2768630.1"
                     /translation="MSKDYAKLALEMHEINKGKVSVESKVEVKTKDDLSTAYTPGVAE
                     PCLKIHENQDDVYIYTSKGNLVAVVSDGSAVLGLGNIGAEASIPVMEGKAILFKQFAD
                     VDAFPICLKTNDVDEIVKSVELMEPVFGGINLEDISSPRCFEIEERLKKSLSIPVFHD
                     DQHGTAIIVAAAIINSIKLIENKKIEDLEIVINGAGAAGIAIAKILLNMNVKNIILCD
                     RSGALEASIENLNYVQKEMLKVTNIRNEKGPLKDIIKGKDVFIGVSGPGAVTKEMVES
                     MSEKPIILAMANPTPEIMPEEAKLGGAFIMGTGRSDFPNQVNNVLAFPGIFRGALDVK
                     AKEINEEMKIAAAYAIANTISDEEICPEYILPDVFNKNVVKNVAKAVKEAAIKTKVNR
                     I"
     gene            12043..12306
                     /locus_tag="PC466_001238"
     CDS             12043..12306
                     /locus_tag="PC466_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HDF2768631.1"
                     /translation="MEETKFCQCCAMPMGQTDELYGTNKDGSKSTDYCSYCFKDGEFT
                     ADISMEEMIEVCIPHMLQSNKDMTEDEARTMMNNFFPTLKRWK"
     gene            12832..13515
                     /locus_tag="PC466_001239"
     CDS             12832..13515
                     /locus_tag="PC466_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2768632.1"
                     /translation="MSSILLVEDDLSLIYGLEFSIQKSGFSIDIARTVKEAMQMYEEK
                     NYDLLLLDVSLPDGNGFQICEKVREVSNIPIIFLTASDEEVNVVMGLDMGGDDYITKP
                     FKLNELISRIKALLRRYNVASNVNELSSNNITIKLLENRVFKGEFEVELTTAEYKLLC
                     LFMKNKNIVLTRKNILDKLWDGNGSFIDDNTLSVYVRRLRNKIEDNPENPKFLLTVRR
                     MGYKWNVIK"
     gene            13526..14767
                     /locus_tag="PC466_001240"
     CDS             13526..14767
                     /locus_tag="PC466_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2768633.1"
                     /translation="MKIFSNKDIKIFFLILISILVMFIIVGQIVVISITNNYKKTLIE
                     HDYNIAGYLYSIGVDKSKIPSAFVAHEDKYILKGKEILDTAGYGFDIDVSFTPSVKLF
                     QSKYIKTMSIYLLVFFTMIIFILYMYFFRQQSKIEEASYKIDLFMNGNINERLNTYEE
                     GSLSKLFSSIDVMSTSLNTHILKEKQSREFLKNTISDISHQLKTPLTALIMYNQILQE
                     ESHNSDVVEAFVQKSQSELERIETLIKNLLKITKIDSKTIVLNKNNVNLKNLIVKILY
                     SFETRAEKEGKVISINGSENTLLFCDYEWMSEALSNLIKNALDNTKENDKITIEWFET
                     TITTIVSVKDTGNGIHVEDIHHIFKRFYRSKFSKDNQGLGLGLPLVKSIVEQHNGTIS
                     VESKLSQGSTFTISFLKLTNM"
     gene            14839..15522
                     /locus_tag="PC466_001241"
     CDS             14839..15522
                     /locus_tag="PC466_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002574824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2768634.1"
                     /translation="MDILVVNNLCKTYGNGYTKVEALKDVSFTVSKGEFVTVVGESGS
                     GKSTLLNLLGGLDTPTSGRIFIDGKEICSMKEEKQTIFRRRNIGFIFQAYNLIPELTV
                     EQNIIFPLLLDYKKPDTIYLDEVLTILGLKDRKNHLPNQLSGGQQQRVAIGRALITKP
                     SIILADEPTGNLDSKNSNDVISLLKVTAEKYNQTIIMITHNTNIASTADRILQVSDGV
                     LTDLGVNRE"
     gene            15519..17849
                     /locus_tag="PC466_001242"
     CDS             15519..17849
                     /locus_tag="PC466_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HDF2768635.1"
                     /translation="MRSYLELVPQYAKVHKKKNRTTILCIIIAVCLVTAIFGLADMAI
                     QCQKIQFIKDDGNWHIVIRNIDEKFISEINSRVDIAHHGRGQVVDSGEFKSKEILIQG
                     LDEEVAKQFNLEIIRGRYPIGENETLIDEDAVKSFNLKIGDFIKIKLADGRNKNYKIV
                     GEYSSISSLRATDKHGLILSILGTQAIKKSETYDYYYITFKEKVNIRKATSDIKNTFN
                     LSDKQIGKNERLLSIIGQGDSDFSKPLYLTAGLLFVLVLVASIIMIYNSFNMSVIERV
                     KFFGLLRCLGSSKHQVKKFVVLESLILSIKAIPIGLVLGSLVTIISSIFLKYVNELFS
                     SMPILKVSFIGIAFGIIVGFLTVILSAIIPAKKASRVSPLSAVRGNLMSKEILNNGKT
                     SKVANTGSFKIETSMGLNHAFSRKKSFVLMTSSFAISIILFLGFSVLIDLMYQGLKPM
                     KPEAPHISIVDPNFKSVLTKEDINEISNIKGVKKVYSRMMTDIEATYNGKKTKSQLIS
                     YEKYQFNWAKKYLLKGEVNENKLQSENLALVEEGHGFDIGDKIYIKNRNAEKELEVGG
                     ILSSIPFEAKDKYIGNIITSENTFTNITGIKGYIIMDIQVDKDTPGDLIENIRRVVDD
                     NLEVRDKRQSNLEVKNSFYTMATFVYGFVFIIAIISMFNIINSMNISVTSRKNYYGVM
                     RAVGISNRQLRRMVIVEAGSYAMSGCLLGSILGLMLHRYMFISLVSSMFHLEWQVPFN
                     LLLITVLTMIIITLLSVRKPVKKICELDIIDSINAQ"
     gene            complement(18030..18872)
                     /locus_tag="PC466_001243"
     CDS             complement(18030..18872)
                     /locus_tag="PC466_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HDF2768636.1"
                     /translation="MINIGDFNKLTVKRKTEFGYFLDGQTNNTKDDILLHNRLIGKNE
                     INIGDEVNAFIFKDSDDRTAATLIPPLAKVGDVAHLKVVDNTDIGTFIDMGLPKDILV
                     PFKAKTYPLFRDEKYLFYIYLDKSKRIAATTDIDSYLLTDHTYNVGDIVTGVVYGFQT
                     NNSAMICVDNKYAGVILHNEYFTELKAGDVLENLHVIKIYEDGKLGLSPRGNRKDELD
                     TLENKILSYLEGSDGYMRFNDKSDPKDISILFNSSKKNFKRALGVLMKKGLIYQDEEG
                     TYLK"
     gene            19167..19901
                     /locus_tag="PC466_001244"
     CDS             19167..19901
                     /locus_tag="PC466_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2768637.1"
                     /translation="MKIVNKSSNIPLHTQLSSIIREMIETGELKEGDAIMPERELCNI
                     QNVSRMTVNKTIVGLVTEGLLYRVQGKGTFVAKQKKKYQFSNVKGFTDVMKEKGVNIK
                     TDILSFEMELPDDLVKRKLGISDNTTNIYKIVRLRYTDGEPFGLEIVYLSEEMCKGLT
                     KGILDNSSLYRVLNEKYGYKIQKAEQVMEPVILSDEESKLLETDEGALALKLHRNSYN
                     REGSPIEYTISIFRTDKYQYEIVLSE"
     gene            19911..21044
                     /gene="nagA"
                     /locus_tag="PC466_001245"
     CDS             19911..21044
                     /gene="nagA"
                     /locus_tag="PC466_001245"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HDF2768638.1"
                     /translation="MKCLINGKIILKNQILENKVLVFDEKIIDIADSVPKDCEVIDAD
                     GKYISPGLIDIHIHGNMGKDTMDSTDESIETISKSIMRHGVTSFLPTTMTMDKEHVYD
                     ALEVIKKAQNRKLEGAQVLGAHLEGPFINENYKGAQNEKFIINSKYEFIKEYKDVIKV
                     ITYAPEKDIDFDFTREIKRCTDIVLSIGHSNANYDQAKEAINLGVTNITHMFNAMTGL
                     NHRDPGVVGAALTTNVYSELIADTIHINKDLFQFILNNKGKERLILITDSIEAGGLED
                     GNYSLGGQKVIVKGNEARLENGALAGSVLSLNKMVFNFLDNTNLKVNEAINLASLNPA
                     TSLGINDKKGSLEIGKDADIAVFDENLDCKMTLCLGDVVYKNI"
     gene            21143..21892
                     /gene="nagB"
                     /locus_tag="PC466_001246"
     CDS             21143..21892
                     /gene="nagB"
                     /locus_tag="PC466_001246"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012425552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HDF2768639.1"
                     /translation="MRVLVCKDYDGMSKKAAEMIAAQIVLKPNSILGLATGSTPVGMY
                     RDLVKKYNDNIVDFSDVMSFNLDEYYKLPISNDQSYDYFMKENLFNHVNIKLENTHLP
                     NGMADDIEKECLNYEASIDAAGGIDVQVLGIGRNAHIGFNEPDTKFAKRTHVVELTES
                     TIEANARFFKSREDVPKKAVSMGIGSILKSKKILLLASGEEKADAVYNTVYGDITPEV
                     PGSILQLHKDTIVIVDEAAASKLNPKDYKLV"
     gene            22067..22339
                     /locus_tag="PC466_001247"
     CDS             22067..22339
                     /locus_tag="PC466_001247"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768640.1"
                     /translation="MLKIIMFSGILSSIIKLPIIGILPIGNIKKNTGISDSKKDGKQR
                     RSNLGISIYQLPSFLYSLINNSVPSNKPIPPEEIKLIKMYLLKSCI"
     gene            22999..23703
                     /locus_tag="PC466_001248"
     CDS             22999..23703
                     /locus_tag="PC466_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2768641.1"
                     /translation="MSKLIYIADDEDNIRNLVKTFLKNEGHDVMDFKTGDELLEQFNI
                     KECDLVILDIMMPGSSGFEVCTKLREKSTVPIIMLTARDTDIDYITGITLGSDDYFTK
                     PFSPMSLVMRVKSIFRRIEFEKKQNYDKYSNSIDMELKFGDVIINKKNKIVTSKNVNI
                     DLTPNEYNLLTYLFENIDRAVSRDELLNKIWGYDIEVETRAADDTVKRLRKKILDTNI
                     LIETVWGFGFRLKEKS"
     gene            23705..25192
                     /locus_tag="PC466_001249"
     CDS             23705..25192
                     /locus_tag="PC466_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2768642.1"
                     /translation="MNNGNDKNRIGKIKSKFKLKFSKKNISIKTRILLSILCLIIIVF
                     MIILVSFNVFLDTYIKTTANEELTKSTEIVEHMDSNFRPIKPPQDDGKLPPKVLSNFM
                     RNVQDKVRMAETQSDADAMVVDSKYNLIFPTREDDFLKNVDEMELIRECIQNEKLDLN
                     SDENTRISTRNKDYYISTVKITSIYGEQDKYLILFIDISKTLNLAQKINIVLISVMCF
                     AGILAIFTAVILSEKIAKPIKELCEFAKKMGQGDFKRTYFDFSDKELVELSTVMNKSA
                     EYLDKYDNEQKIFFQNASHELRTPLMSIKGYAEAIKYNVIDSKHASDIILEESDRLSD
                     MVEDLLYISKIDNITKDFELVECDLREVFSNCGARQNVRAINKGIKFIYEFDEEMVLF
                     ECDEKNISKAFMNLIENALRYAKSEIKIVCKYNQKNIVVIIEDDGIGIKKEDLPHVFE
                     RFYKGVGGNHGIGLSIVKSIVNKHGGRIYVENGKKGAKFTILFKL"
     gene            25397..27010
                     /locus_tag="PC466_001250"
     CDS             25397..27010
                     /locus_tag="PC466_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HDF2768643.1"
                     /translation="MKEQLIFNITNLVTVVFEAFVIHMFLSDFLGQKEGYIKVVRYAK
                     LGFIICLGFCNLITLNPKITMPLIFILIFSTSFLYKGNLKTRLFTTVLLSIFFILSEI
                     VVTSIFVLFVKEGFEIMLENNSIRVLATILSKIVFLLTCKIICLFKKDVHLDMPIKYW
                     LPLFLIPIFSLFLSVSIFDVSKFFSLESLKFLSLISSVGILYINFIVFYLFKFIIDKT
                     KLSMKYEILEKEIIHKEELRLSNECYKIIVEQTDSVVFEWNIKENKSFVSQAWTEKFG
                     YNNACKNIFKEIKDKDLVHSEDKAIFEGFLESIKKKNIHSQAVYRLKKSNGEYIWCRT
                     SITSIYNDENELLRVVGVIVDVDSDIKKYEELRTRAESDSLTNIYNKGTFEKLVEETI
                     VMNTGDKKDALFIIDLDDFKEINDNFGHPFGDFVLKTFADKIQASFGNKDLVGRIGGD
                     EFVVYMQDYVTEVNLHKKAKELNRVLSDNYTDLSFSFDSSVSIGIARYPQDGTSFFEL
                     FKNADRALYSIKASGKNSYCLFEEELYVQ"
     gene            complement(27700..28530)
                     /locus_tag="PC466_001251"
     CDS             complement(27700..28530)
                     /locus_tag="PC466_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF2768644.1"
                     /translation="MSQVSKNYFTTGEFAKICGINKKTLFHYDDIGLFSPELKKENGY
                     RYYSYHQLSIFGIISSLREVKMPLKEIKAYIDKRTPNLLIELLEKKTIDIKNEIEKLN
                     NIQALMESTISFTKNACNIDANTITLKEHEEEYLVKTPITYKEQFLGDEEENFLYECI
                     NFMDNYELSDYGTIGSIIKGEDIINKDFESYSYLFTKVNKEYKKYPVSIKPKGLYVTA
                     YHKGSYETIYKAYEKLLNFFNQNNLRIGDFVYEEYLLYDISVRDSNEYLTQISAEVKI
                     "
     gene            28603..30330
                     /locus_tag="PC466_001252"
     CDS             28603..30330
                     /locus_tag="PC466_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2768645.1"
                     /translation="MKKLIHFLKPYRVLIVVVLIFTFLQTLGTLYIPTLTANIVNNGV
                     VKGDIDYIVKTGLIMMIVAGITALSAVLVCKVSANLSSGFCRDIREAVFVKSQDLSIN
                     DFNNIGTASMITRSTSDITLIGQSVFMFIQLVLPAPIITVSGLFLAYSIDKAMTIIIV
                     VVMFLFMLSAFLVGKKLIKLFKMMQIKMDNMNRVLREVVTGVRVIRAFNREHFEKKRF
                     DRTAIDYSETAISINKVFAVLMPIVMLIMNLGIVSIIWFGGMRVSNGNMEIGHIMALI
                     EYCILILFYLIMGVMVFMYIPRAGACADRVNQILDIEPEIVDGNGRKDTVSERGHLVF
                     KNVTFSYAQSEEPVLNNITFEAKSGEVTAIIGSTGSGKSTIANIIPRFFEIQSGEISI
                     NGQDVKKIPQKELRDKIGFVPQKAFLFSGTIEENIRYGKEDASIEEIKHAASIAQADE
                     FISDMEDKYDSFVAQGGNNLSGGQKQRISIARALVRKPEVYVFDDSFSALDFKTDKRL
                     RKALKNEIKDSSAIIIAQRISTIMDANQIIVLNDGKIVGIGKHKDLLENCEVYKQIAD
                     SQLSKEELA"
     gene            30367..32229
                     /locus_tag="PC466_001253"
     CDS             30367..32229
                     /locus_tag="PC466_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2768646.1"
                     /translation="MSEKRIDEQDIEVLSFEDGMSAEKVKDAKKTTKRLLKYMAKQKF
                     KILIIFISVLISSALTVLAPMVMGKAIDQLFNGIKTAVQTGTKFSVNFSTMGGIVSIL
                     LGLYLISAVFIYIQQYIMSGVAQNLVLSMRKDLSDKLNKLPLKYYDSHKKGETLSIVT
                     NDLEKVADSLQEGLMQLITAVVTVVGSIVMMISISVPLTIVSAITLLVSLGITVVIAR
                     KSQERFSENQKALGELNSNIEEIFTGQIVVKAFSKEKDTIRNFKILNQNLYNASRRAQ
                     FSSYAISPIIRFINLIGYVIIAVVGGIFASTGAMTLGSIQAFIQYVNQASEPTTEISY
                     IVNMLQAAIASAERVFTVMDEVEEIKDEESSKVISMPKGKVQFEHVKFGYSDDFILMK
                     DININLNAGDKIAIVGPTGAGKTTLVNLLMRFYEIQGGRITIDGVNIKDLKRGELRTM
                     FGMVLQDTWLFNGSIKENIAYSKSDATMDEIVRAAKSARVDHFIRTLPQGYDTILTED
                     ASNLSQGQKQLLTIARAILSDPSVLILDEATSSVDTRTEVEIQKAMNNLMKGRTSFVI
                     AHRLSTIRDADLILVMKEGTIIEQGSHKELIEKKGFYEELYNSQFSSEYDEEVV"
     gene            32562..33251
                     /locus_tag="PC466_001254"
     CDS             32562..33251
                     /locus_tag="PC466_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyphosphate polymerase domain-containing
                     protein"
                     /protein_id="HDF2768647.1"
                     /translation="MNKKLNYRFEMKHKITEADVLALKSRLYPIMKKDENASKDGKYL
                     IRSLYFDTPEDKALLDKLNGVAIREKFRIRFYNNNCSYIRLEKKIKHYNMTSKLSTNL
                     TKKEVINILNNDIEFLKESTNCLLREFYLKLKCERLEAKSIVDYNREAFIYPVGNVRV
                     TIDSDIKTSVNSIDLFNKDLPTVSVIDENMTVLEVKYDEFIPDFIKDLIQINKTTSTA
                     VSKYASSRLYI"
     gene            33356..34042
                     /locus_tag="PC466_001255"
     CDS             33356..34042
                     /locus_tag="PC466_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4956 domain-containing protein"
                     /protein_id="HDF2768648.1"
                     /translation="MILIMTFNDIFKSSFIENVSGFSFVDSALALGSAFLVGLFIYMV
                     YKKTYMGIMYSRPFNVSLVALTMLTTFVILAVTSNVVLSLGMVGALSIVRFRTAIKDP
                     MDLVFLFWSLGSGIVLGAGLIPLAVMGSIIMGLILIFFSNKTISETPYILMVNCNNED
                     SEDIATDKIKKVFTKYQIKSKSVTPEKGIELVFEVRMKYGETSLINDLSQVDGVTNAV
                     LVSYNGDYVA"
     gene            34059..35966
                     /locus_tag="PC466_001256"
     CDS             34059..35966
                     /locus_tag="PC466_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CotH kinase family protein"
                     /protein_id="HDF2768649.1"
                     /translation="MKDKKFTLLISIMIIFLCAVVGVYSTSSNKSVDLYSDVYIEKYF
                     NRDKVMEVNIEIDESDLKDMNENAIKEEFKVAKVTVDGDTYGNVGIRTKGNSSLTSVA
                     NSDSDRYSYKINFDKYNTSQSMEGLTQLNLNNCYSDPSYMREFLTYSICEEMGLATPE
                     FAYAKVSINGEYHGLYLAVEGLKESYLENNFGNVTGDLYKSDEGSSLQYKGDDPESYS
                     NLIVESDKKTADWSKITKLLKSLDTGEDIEKYLDVDSVLKNIAINTALLNLDSYQGSF
                     AHNYYLYEQDGVFSMLPWDFNMSFGGFSGFGGGSQSIAIDEPTTGNLEDRPLISSLLK
                     NETHKTKYHKYLEEIVTKYLDSDYLENMTTKLHDMIASYVKEDPTAFYTYEEFEKNIT
                     SSIEDSSDNKGFGNKGFDNNNSNNSDSNNNSNSENKRSGNQSDKKEVNAELTSSVVKT
                     NTDNETENKTTNDSESKNNTDKDKSGNDNNQKLEGPRGKGGKSIPGVLEVAEDMSKTI
                     KSQLSGETYSTKQNSGDESSSGIKGSEKFDEDMSGMPEPPEGMDGKMPPGMGNMDKGD
                     MNGKNGNMNMDRNQDNPREAGGFGNRGGGSVSKTTTYFKLILGGASMIIMSIMLVGVS
                     RVKRRRFIKSK"
     gene            36419..37108
                     /locus_tag="PC466_001257"
     CDS             36419..37108
                     /locus_tag="PC466_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768650.1"
                     /translation="MLQKVLWKFLKLVVGLFICSVGIVLTINCNLGLSPWDVFHQGLS
                     NHIGITIGTASIIVGSIVVIADVVLGENVGWGTVFNMLLIGFFMDLLLYSNLIPEADS
                     LFVGIIMLILGLVLLSVGMVFYMGSGLGSGPRDGLMVAIQKKTGKSLKLIRGTIEVGA
                     LIVGFLLGGKVGIGTIISAFGLGYFTQMVFGLFKLDCSKIKHRFIVDDIKFIKVYMSG
                     EKKAAVQNIVK"
     gene            37544..38083
                     /locus_tag="PC466_001258"
     CDS             37544..38083
                     /locus_tag="PC466_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007286148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2768651.1"
                     /translation="MDIGEKIKRLRTEKQLTQEELANRCELSKGFISQLENNLTSPSI
                     ATLIDILEILGTNLREFFNEIDDERISFTKEDMFETEDEDLKYKLKWLIPNSQKNEME
                     PIIITLYPGGQYKEEKPHEGEEFGYVLAGSIYVHIGEKKNKVKKGESFYFRPKANHYI
                     SNEGKTTAKVIWVSTPPSF"
     gene            38102..39145
                     /locus_tag="PC466_001259"
     CDS             38102..39145
                     /locus_tag="PC466_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011721317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2768652.1"
                     /translation="MVENIIELRDISKHYEELTVLDNFNLDIKKNEFLTLLGPSGCGK
                     TTTLKIIAGFEYADDGKVLFEGKEINNLPPYERQVNTVFQKYALFPHMDVYENVAFGL
                     KIKKTPKDVIDAKVKEVLKLVALEGFERRQVESLSGGQQQRIAIARALVNEPKVLLLD
                     EPLGALDLKLRQEMQIELKRIQKKLGITFVFVTHDQEEALTMSDTIVVMYKGKIQQMG
                     TPQDIYNEPKNSFVAKFIGESNIFDGIMIEDYKVNFCNRDFECVDKGFEKNENIEVVI
                     RPEDIKMVKPEEGMLKGKVTSTVFKGVHYEIELNENGRLWILHNTKNAEVGTELGMDI
                     YPEDIHIMRKENN"
     gene            39147..39983
                     /locus_tag="PC466_001260"
     CDS             39147..39983
                     /locus_tag="PC466_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2768653.1"
                     /translation="MKRKSFLAYPYVVWSAIFVIIPLILVVFFSFTKESGGGYAFTLE
                     NYKEVIDPIYMKVFGRSILLAGGATLICLIVGYPVAYIISKARVSRRGSLILLFILPM
                     WMNFLLRTYAWVAILGKNGLLNTFLGWFGIQPLAILYTNFAILLGMVYNFLPFMVLPI
                     YTALSKMDNDLINAAHDLGANNMTVFRKIIFPLSLPGVMSGITMVFMPAVTTFAISRL
                     LGGGKIMLVGDLIEQQFTVVGDWNFGSAISIFMMIVILISMSIMSKFGDESDKEGGGL
                     LF"
     gene            40088..40762
                     /locus_tag="PC466_001261"
     CDS             40088..40762
                     /locus_tag="PC466_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2768654.1"
                     /translation="MARWNGFTWKWYGQLLQNESIMSALYYTIVIAILASVISTIVGT
                     ISAIGIHKMRGKSKKLILNVNYLPILNTEIVTAVALMSLFVFVKMEFGFTTMLLAHIM
                     FCLPYVILSVLPKMKQLPDNIEDAAMDLGATPIYALRKVILPQIKPGIVSGFLIAFTM
                     SIDDFIISFFNAGNGVSNLSIEIYGMARRGIKPEINALSTIMFAVVLGLLLLANKKES
                     IVRGIK"
     gene            40762..41814
                     /locus_tag="PC466_001262"
     CDS             40762..41814
                     /locus_tag="PC466_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter
                     substrate-binding protein"
                     /protein_id="HDF2768655.1"
                     /translation="MIKFKKTISLIAVGMMTVTLFTGCNKATDSTKVLNVYNVGDYID
                     ESLIDKFEKETGIDVQYSTYDTNEMMYQKVKSGSTHYDLVFPSDYMVEKMKNEGLLEK
                     LDFKNIPNMKYLDKSFLNPVYDKTNEYSVAYMWGTLGILYNKKEVKDPMDSWNILWNP
                     KYKGNIMMFDSVRDTIGITLKKLGYSMNSVNPKEINEAKNLLMKQKDLVLAYVNDEGK
                     DRLLGGEVAMGMLYSGDAVTLMEQNPDLDYAIPKEGTNKWVDAMCVPTTAQNKKEAEL
                     FINFLLDPENAKVNAEYIGYSTPNTGALKLLDPEITQNPVAYPSKEVLDKCETFEDIG
                     ENIKLYDKAWIELKSK"
     gene            42258..43106
                     /locus_tag="PC466_001263"
     CDS             42258..43106
                     /locus_tag="PC466_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDF2768656.1"
                     /translation="MNRINKKIDLLILALLVFIFLIVGIVILSIRTENKLNVFIMLAI
                     IFFIIMLTYLSNSVVGLITSSIIIFMYTSYILYNNITHNMDVEFISYMWIIATPVSSI
                     IMGNLNKSINELQNTNKKLSEQYKELVTIDSETGLRNLKIFYNDVNMEISKSIRHNTD
                     FSLMIVKLPYYGNLQTIFGENKTNKIVKYIGSNIIECTRNEDIIYSLQKDMIGILMPN
                     TSLEGSKVVKDRIKKRIKELNLDLNNRGKYVNIDVKIAFLQYKSSFGDSINFKNIVEE
                     ELQYDV"
     gene            43096..44760
                     /locus_tag="PC466_001264"
     CDS             43096..44760
                     /locus_tag="PC466_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HDF2768657.1"
                     /translation="MMFKIFNKSLLKLVIVLSIVLTISNFSLFSYASEITSSTDKVLI
                     IYDSKKETAYNRDILNIMRTLLGRFSSDIELLKLSNYDGEINENYYSHIFILGINENS
                     YNNDKNTKNLISSLNSYKVTICWLGYGIENLLEHKKYNLDYVGKTNNIVSVNYRGKSY
                     NLDEHYVFNIVESKDTSNKVIGSINDTLNKYPYIINDKNLFYVSKLDLDGVLFYIFCD
                     SLNDIFNIKTFDKGRIFVRIEDVHAFREPKNLVEIADYLSSKNIPFTIALIPAYVNPK
                     NHKVITLSESPEIVKAIKYMQDKGGTVILHGYTHQYKKEEVSGEGYEFWDGKKDEPLK
                     ENMKIFVKDRVLNGLRVCIENGIYPLAFEAPHYAMESEGYKELKKYFSTYMGQHQNND
                     KKFSTNTYPYIIRDTEEFNIFIPENLGYIDPEDKFTFQNIKENLDKLSIVRGFSGGFF
                     FHSYLNIEYLKNTIEYLEKQNIEFMNLRDFNNWVKVDEIQIRNNGDEIIVNYDKDLDE
                     ITKSDTRFKYISNISKILIFIVSISVLIFVIIFIYFKRIDKKKFLK"
     gene            44809..46065
                     /locus_tag="PC466_001265"
     CDS             44809..46065
                     /locus_tag="PC466_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003362983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDF2768658.1"
                     /translation="MRDLNVSEYLFVFSLFSIWSLLLINIILAMGGYIFYFKNFDKEI
                     KEIDEYPMISILVPAHNEAKVIGRTVESLLLLNYPKSKMELIVINDNSSDNSKEILEN
                     IKDRYNNYNFTIINTDSLTGGKGKSNALNIGYKVSKGDFIAVYDADNTPDKNALRYLV
                     QTIVMNDELGAVIGKFRTRNKNKNLLTKFINIETLSFQWMSQAGRWQLFNLCTIPGTN
                     FILRRSIIEEIEGWDSKAIAEDTEISFRIYKLGYKIKLVPQSITWEQEPETVKVWIKQ
                     RTRWAKGNIYVLMKYIKNIFKQGRNKIVFDIAYFFSVYFLFLTTVIISDILCVLSISK
                     LVEISIPINFFLIWILSYLLFIIEVSISLTIEKGEATIENIFIVAIMYFTYSQLWLFV
                     AIKGMIEYLKDIIFKREVKWYKTERF"
     gene            46088..48169
                     /locus_tag="PC466_001266"
     CDS             46088..48169
                     /locus_tag="PC466_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis cyclic di-GMP-binding
                     regulatory protein BcsB"
                     /protein_id="HDF2768659.1"
                     /translation="MKKFIISIISLVLFFSNISLIYKVNADETKVKNYKFERDITIDG
                     VIGSNSTFFEVNKNWDIEEVLLHLNFSKSQILNGDVSSLTVLINNVPIKSIKLNAKTN
                     YKNTLEVLVPKDYIIQGYNEIKIKTYKTISDKICQDDSNTGNWMVIHKESYISIRYKQ
                     KKVENSINEYPYPYAEIENNHKLDTTIVVPDNMTRGETTAVFNLASSFGKITKNDDLK
                     LDVKLYSEMKNWSDDNIIYIGKPENTAEEILDILSIKEQTLLSSNCIIKQVDSPYNKN
                     KKMMVVIGSNEDDLIKASNLLIENRLSNQVLSSSVLVNKETNIKINREQKLNLGHLTL
                     KDLGYSDFLLEGAFNQQALFDVKIPTGKVLDDGSKIILNLRYSDNLDFEKSLVTVSIN
                     DVIVGSKKLDRSHSNNDKLELKIPKDIDNKNYYQVKLTFNLSIKNSNCVTRESNNPWA
                     YVSNNSYLALSTKENETLSFENYPYPFVRDDEFNDLTVIMPDYSGSQAMTWMFRLGVT
                     LGTNINSHNGNINVIRGKEFSDKYKDTNIVVFGVPHNNSVIKMLNNNLNIKFDKNYSN
                     FISNDKISFIDDYGKNISTIQLIKSPYNNQKNIMVISSMNEKNLYLGMDYLLNKSKVN
                     DLKGDTLIIDEYGEVEDLAYNLKPKKEVKDSSWNMSINKTTKVFLMISFITIIVVMIL
                     SMLYIKKYKRR"
     gene            48206..49291
                     /locus_tag="PC466_001267"
     CDS             48206..49291
                     /locus_tag="PC466_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HDF2768660.1"
                     /translation="MRKYMNKFKLKRSILISLIILIFIFIVYFVSIELKDGSLVNNQY
                     KGKIKSANLSVDYEINQVMKDIDKLGLNTVNVPIIINVESINSDIMSIDNNSKEKAIK
                     LIKKLNKKGISTILEAYPWVENGKLYETDWNPINKKRFFYTWQNAILNELIIDVANPL
                     DVNVLNIGSNFVHLEEYQQNWGEIIDFVQSKFDGLVTYRTNWWYTKKDDSSSKLFYEQ
                     KLNNNFFDKLDFISIAAYFELSNKPVNTVDELISALHSSTVNNRGQNIKQEIYNLYKA
                     HRKPIFFGELGFSNRESASSQPWNHTPSKAVNGEEQARCFEAYKKVFENEDWINGFSV
                     FCVGKIDDEKNFYPSKESIKVIKSWYE"
     gene            49345..50469
                     /gene="wecB"
                     /locus_tag="PC466_001268"
     CDS             49345..50469
                     /gene="wecB"
                     /locus_tag="PC466_001268"
                     /EC_number="5.1.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (non-hydrolyzing)"
                     /protein_id="HDF2768661.1"
                     /translation="MNDIKVMTVFGTRPEAIKVAPLIKELEKRENIKSIVCVTAQHRE
                     MLDQVIETFNINVDYDLDIMEKGQSLNDITCKILNKLPLILNKENPNIILVHGDTTTT
                     LATSLTAFYNKALVGHIEAGLRTYDKYSPFPEELNRQLTGIIADMHFAPTNLARKNLI
                     SEGKPNNNIFVTGNTAIDALKMTIKENYNHPIIDEIGNDRMILLTSHRRENLGKPMKN
                     IFRAIKRIVDDFEDVQIVYPIHLNPKIRTIADEIFGKFPEKIHIIEPLDVADFHNFLN
                     KSYMIMTDSGGIQEEAPSLGKPVLVLRDKTERTEGIEAKTLKLVGTNEDRIYNSVSDL
                     LINKDSYVQMSKASNPYGDGNASKYIVDIIIKKFNCKYLN"
     gene            50547..51521
                     /locus_tag="PC466_001269"
     CDS             50547..51521
                     /locus_tag="PC466_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HDF2768662.1"
                     /translation="MARKLIKNLGKSKSVKRVKLLFKKIFITVFIVASIVAIFNITKY
                     FEELYKVRDLKSTKIEYYMDVADEAGDGKVQLSWKALLAIDMVIHDEDLSNIKKKDTL
                     DIGEKFIVEDKNDKGEKVYKVKKFNKVLSELKFDSSQKSRARKYMKDLEYTYLGNKQL
                     DSSDEKIKFIKKLEDSAIREYIDYGILPSVTIGQAILESGWGNSKLTKQSNNLFGIKA
                     DKAWKGKSVEISTSEHYNEKIVASFRSYNSLQDSVKDHSLFLINNKRYRKHGLFEAKD
                     YISQAQALENAGYSTAEDKKGNRIYAELLIDIIRSYNLQLIDNKVETK"
BASE COUNT        20593 a         5230 c         8921 g        16920 t
ORIGIN      
        1 ataaatcaaa aataaagtta tagtttttaa tattaattaa gaatgatgaa atatgaataa
       61 agattttaca aataaatctt aagctatctt atttaattct aatgcaggaa gaaggtaaat
      121 gtatattgaa aaaatcatag aaatagaagt aaacaactta aacaaataca aaggtttgca
      181 aaagaagtaa tataattata tacaatgagg atgtgagtat gatgaacaga ctaaagccaa
      241 gaattttagg tattagtatc ttgtttatta ttataattat tttaacatgt ggagctgttt
      301 tcaagtttaa atttaaatta gataataaat taaaagaaac cacacataca tatttgtctg
      361 agtttacaga acacaatata attaatctca agacaagact tagtggtcaa tttgacatgc
      421 ttgaatctat tgctaacttc ataggaaact tgaataatat aaataatgaa atggtgattg
      481 ctttaatgga ttctgatgta aagcgaagtt ctttaattag aatgactatc tctacattag
      541 atggggaatg ttattctaat gatggaatca cccataatgt tcaagataga gattatttta
      601 aaaaagctaa aaatggagaa aagaatattt cagagccttt aaaatctatt gttaataata
      661 aagaaataat agttttatct accccagttt ataaaagtgg gaaaatagtt ggtgttttaa
      721 gtggaattta tgattcaaaa aagttaaatg agttattagg attatctgca tttgatgaaa
      781 aagcagatgt ttttgttgca aagaaaaatg gagatatagt tgctcaaaaa acaaataaaa
      841 atagaaagac gatatcatgt atatttcagc tttttgacaa agataattgt gatgaagatg
      901 attgtctaaa aactataaaa gaaaatatga aaaatgataa gtctggatat tttaattata
      961 acttagataa tgaaaaattt atgttaaact atcagccact tggagttaat gattggtatg
     1021 ttttttctgt tgtgccaaat aaaatagtgt ctattcagtc agagaatata tcttatgatg
     1081 tatatatttt tgcattagaa atactactag ttatattgat ttttataata tatatagcat
     1141 gtattataaa taataacacc aaaattatta taaatgaaaa agaaaaattt aaagtactca
     1201 ctgataatat attaggaggg gttaaaacct gtttaaaaga tgaatatatg actatgacat
     1261 atgtaagtca ggggttttta gagcttacag gttactcttg tgaagattta aataaaatat
     1321 ttaaaaatag atttaaagac atgatttata aagatgattt agacaagttt aattgtatta
     1381 ttctaaatca attagaaaaa caagataaaa ttgaagttga atatagaatt gtaagaaaag
     1441 atggaagtat aatttggatt ttggagagaa gtaagtctat aaatgataat aaaggaagtg
     1501 agtgtattca gggagtttta actgatataa cagaacttaa gaaaatacaa gaagagttag
     1561 attcaaaaag atttgaaata caggctatca atgatagtat tgttggtgga atagtgataa
     1621 ctgagataaa tgatgatttt gatagtatat atttaaatga aggttattta aatatgattg
     1681 gatatacacg caaacaactg gaagatgagc taaataataa attaatcaaa cttattttta
     1741 aagatgatag aacagaatta attaatagta taaacaaaca actcaaatta agtgatacat
     1801 ttgcatctga acaaagagtt gaaaaaaggg atggtactat tatatggatt ttattaaaag
     1861 gaagaaagat aatttatgat aatggaaaat ctgtactttg ttgtgttatt gtagatatca
     1921 cttctgctaa attattagag caagaactta aaaagagtga agaacgtcat gaaatcattc
     1981 taaagcagac gcaaaatatc ataatagaat gggatataga aaaagataaa atgaatatat
     2041 cacctaattg gtataataag tttaaatatg accctataac tgaaaacgca acaaaaaata
     2101 taattaaatc agtagatata tatcatgatg atatggataa gtttatttca ttaattaaac
     2161 ttacttcaca aggtagtgag tatgaagagt gtgaaattag acttagaact agagatacta
     2221 tttacgcttg gtttagtata aaggcaacaa ctttatttga taataatggt aaaccttata
     2281 aagtagtagg aagtttgact gatattgatg aatcaaaacg agaagctgaa aagttgaaag
     2341 aaagggcaga aaaagaccct cttacagatt tgtataataa aaaagcatca caatcactta
     2401 tagaagagta cataacattg gataaaaaaa gaaaaggtgc tttaatgatt attgatattg
     2461 ataactttaa aggaataaat gataatttag gacatttata tggggatgct gtattaagtg
     2521 aaattgcaaa tgacctaata aatctattta gagcaaccga tatagtaggc agaattggtg
     2581 gagatgagtt tattgtattt ataaaagata tttctgaaac aagagatatt ataaataaag
     2641 cagaagaatt ggtaaaaaca tttgaaaggt cttttttagg taaaggacga aattataaaa
     2701 tatcattaag tgtaggaatt gctaagtttc cacaagatgg tatggactat atgacactat
     2761 ttagaaatgc ggatatggct ctttactcag ccaaagggaa gggtaagaat tgttatacat
     2821 tgtatgataa aaaaattgat aaagtccaat atataactaa tacaagaaat gcaggagata
     2881 gtgataatgt agagatgtct tttaaagaac atatcacaaa ttatatattt gatatactat
     2941 atgaatcaag tgatatagaa gtggcagtaa atttaattct aagtattgta ggtaaacact
     3001 ttaatgtgag tcgcatgtat atatttgaaa attcagatga taatcgagta tgtaaaaata
     3061 catttgaatg gtgtaacgaa ggtgtaacct cggaaattaa taatcttaaa aatatttgtt
     3121 acaaggattt aggcaactat cttttaaatt ttaatgcaga tgggttattt tattgtaatg
     3181 atattgaaaa tttaggtagt gatgtgaaaa aagtacttaa gccacaaggc atacgttcaa
     3241 tattacaatg taaaatttta gagggcaatg aatttagagg gttcatagga tttgatgaat
     3301 gttcatataa tcgtatgtgg actaatgatg aagtgaacac tttgacattt atatctaaaa
     3361 cgctcagtat gtttttatta aaaatgcgta ttcagagtaa gctagaagag tctttaacaa
     3421 ttcaaaaatc tgtgatggat aatatggata tatgggcata tgttgttgac aggaatacct
     3481 atgaattatt atttatcaat aaaaaaatgc ttgagtcagc atcaaacact catgtaggtg
     3541 atttatgtta taaagcgata tggaataatc aagataaacc ttgtaaaaaa tgccctatga
     3601 tatatttaaa agatggtgat gatacttata aatcatttat gcgcaataaa aagtttgagg
     3661 tacaggcaaa tataactaca actactttga aatggtttga tgggaaagat gcatgtttaa
     3721 tatttggaag tgaagtaact agtattgaag ctgaagaaaa tacttaaaat actgtgttat
     3781 atatatactt aaaatcgcaa tttgaattta ttagacttaa aatgtctata taaatcattt
     3841 aagttgtggt tttaagtatt ttttatgata taattaagcg ttaagaacaa aattaaaaga
     3901 tacttttgta taaaaaaata tttgttaaat atatattgag caggtgataa tatggaaaat
     3961 aagtttttac caataagcaa acaagatatg atagatagag gatgggaaga attagatttt
     4021 gttctagtta caggagatgc ttatgtggac catcatagtt ttggaacagc aataatatct
     4081 agagttttag aaaatgctgg gtataaagtt ggaataatag ctcaaccaga ctggagaact
     4141 acagatgatt ttatgaagct aggaaaaccg agacttgcat ttctagttaa tgcaggaaat
     4201 atggattcaa tggtcaatca ttattctgta agtaaaaagc atagagaaaa ggatatgtat
     4261 tctccaggtg ggaaaatggg ttatagacca gatagagcta ctatagtata ttgcaataaa
     4321 ataagagaag catacagtga tgttgcaata gtaataggtg gaattgaagc gagtttaaga
     4381 agatttgcac actatgatta ttggagtgat aaggttagaa agtctatgtt aatagatagt
     4441 ggagcagatt tattagttta tggtatgagt gaaaagcaga ttgtagaagt agccaatgca
     4501 cttaatgatg gatatgaccc aaaatatatt agacatattg atgggacatg ctatatttca
     4561 gatacattgg aagaaatata tgataaatat atattaattc catcatataa agaaatttgt
     4621 gaagataaaa tgaagtatgt agaagctttt aaaattcaat atgatgagca agacccattt
     4681 agaggtaata taattgttca acctcatgga agtaagtatc tggttcaaaa taagccagaa
     4741 aaaccactta gtagagaaga actagatgaa gtatatggat taccatatca gaagacatac
     4801 catcctgtgt atgaaaaatt tggaggaata ccagctatag aagaagtaaa atttagtata
     4861 gtaagttcaa gaggctgttt tggtagttgt tcattttgtg caataacatt tcatcaaggt
     4921 agagcagtgc aaagtagaag tgaaaaatca attattgatg aagcaatagg aataacaaat
     4981 ttagatgatt ttaaagggta tatacatgat gttggaggtc caacagctaa ttttagaaga
     5041 ccagcatgta aaaaacaaat tactaaaggt gcttgtaaaa atagacaatg cttatctcca
     5101 tcaccatgta aaaatttaga tgcagaccac agtgaatact tacatttact tagagctgta
     5161 agaaaattac ctaaaataaa aaaggtgttt gtgcgttctg gaattagata cgattatgta
     5221 atggcagata agaacaataa atttcttaga gagttgatag agcatcatgt aagtggtcag
     5281 ttaaaggtag ccccagaaca tatatcagaa gaagttttaa agtatatgca aaaaccagca
     5341 ggaaaaactt atgataaatt tagacagaag ttttttgcta taaatgaaga attaggtaaa
     5401 aagcaatatt tgatacccta tttaatgtct agtcaccctg gttctacctt aaatagcgct
     5461 atagagttag cagagtattt aagagatact cactaccaac cagagcaggt tcaggatttt
     5521 tatccaactc cagggactct atctacaacc atgttttata caggtattga cccgcttaca
     5581 atgaagccag tttatgttcc taaatcaaaa cgtgacaagg caatgcaaag ggctttatta
     5641 caatatagag cacctagaaa ttatgatttg gtatactctg cgttagttga agcaggaaga
     5701 gaagacttaa ttggttttgg acatagatgt cttataaagc caaaaaatga aaagccttat
     5761 tttaatagaa ataattctaa aaaaaatgta tctaaaggaa caaataaaaa caaaaaaact
     5821 aatacaaata acagaagtaa taaaaatcaa caaaaaagtt caactaaaaa aaagaaaaaa
     5881 cattaaagta taaataaaaa tacttaaaaa agaaggatta ttcgataaat taacagaaat
     5941 tagtataaat aaatataatt attttaatga cgttaccttt gggaggaaga gatgaaaaag
     6001 tatatttcta taatattatt agtggtggtg actatggttg ttttggtagg atgttcacca
     6061 ggaaaagata accctaaaaa taaggagcta tcagttgtca aacaagtaaa agtagctgtt
     6121 ccagatggac taccagcagt ggcaatagct aaacttgcaa atgaaaatcc agagattaaa
     6181 gaaggatatg aaacagtgta tagcattgaa aagacacctg aggcgatttc cactagagtg
     6241 atgaaaaaag atgcagatat agctatagtt ccttcaaaca tggctgcaat agcgtataat
     6301 aaaacttcat catataatat tgttggaact gtaggaatgg gttcacttta tttggtgtca
     6361 acagaaaata taaaagatta ttctgattta gttggtaaag aagttggatg tactggaaaa
     6421 ggacttactc cagacataac tataaaaagt cttttgttac aaaaggatat aaattattca
     6481 aatataaaat ttaattatgt aaattcagca agtgaactgg taccattatt ggctactggt
     6541 aaagttaaga caggtattgt tccagaacct gcacttagtg ctttgatgtc taaaaatcca
     6601 gacataaaaa ttataaaaag tttaaatgac tcatggaagg aagtaagtgg ttcaaaagac
     6661 ggttatcctc aatctacttt aattgtaaag tctgaatttt taagagataa taaagatttt
     6721 gttgattctt ttgtaggtca attatcaaat agtatagatt gggcaaacaa aaatcctgaa
     6781 gaattaggtg catattctga aaaaataaaa atatctactg aatcaaagat aataggaaaa
     6841 tctcttgaaa gagctaattt aaaatatatt ccagttaagg acatgattaa agattataaa
     6901 aattactatg agaaattagc taattttgat gataagacat taggaggcaa agtaccagat
     6961 gaagcaatat actttgttga gaaataaaaa aaataaagaa caatttatag ataaaatgga
     7021 ggtaacactt tcttgtgtta tcctcttatt tttatggcaa attattgctt taaaaattga
     7081 taatgatatt tttttaccaa cagtaggtca agtatttaat agtataaaag agattatgct
     7141 aaattctagt ttctatatag atatacttta ctctatgggg agatgttttt ttagtttttt
     7201 actggctatg atttttgcca ttatactttc aatagtatct tatttaaata gattttttag
     7261 aaacttatta aagccaatca atgctttgac acgttcaata ccaactatga tattggtagt
     7321 acttgcactt atttggtttg aaaaggatag tacccctttt atagttggat ttactatagt
     7381 ttttcctata ttgtatgata acgttttggg cgctatattg aatatagaca agaacttatt
     7441 agaaatggct aatgtgtata aaataaggtt tatagataag gtgttaaaaa tttatttacc
     7501 agccataaaa tttcaaatta tatctatact agtatcaaca ttctctttaa gtttgaaagt
     7561 tgctatagca ggagaggtat atagtcaacc tacatatggt attggaacta tgatacagac
     7621 tgaaaaaatt aactttaata catctggaat atttgcatgg ataattattg ttcttttaat
     7681 atctgctatt ttacaaatag cccaaaagtt tttagcaagg agagcttttt tatggaaaag
     7741 ataaagttga gtattgaaaa tataaataaa agatatgata gtcgtattat atttagagat
     7801 tttaatattg atttttatgt aaatgaggta aattgtatcc ttggaaaatc tggttgtgga
     7861 aaaactacac tcttgaacat aataagtggg attattaaaa atgacaccaa caatctaaat
     7921 atcaaagaaa atttaaatag agtaggaaat aagcttgaag ctagttacat atttcaagat
     7981 gatagactta tagactggtt aacagtagaa gaaaatataa agatagttgt aaataaatac
     8041 tataataaaa ctcaattaaa taaaatttgt gatgaatact tggaattggt tggaattagt
     8101 gattataaaa aattctatcc tcagatgctt agtggaggta ttagacaaag agtaaatatt
     8161 gctagagctt ttatatatcc atcaaaaaac attataatgg atgaaccttt taaatctatt
     8221 gatgcaaaga atacacagct tataatggat aatttcagaa atatattaag aaaagaaaag
     8281 agaactgtat tatttgtaac tcataatatt gaggaagcat tgtttttagc agataggata
     8341 tttattttag gagactctcc aattagaata aaaaaaatat taaaaaattc taaggaattg
     8401 gaaaaaaatg aagttttgaa gttgatatag agttataata atactgtcgt tttaaaatat
     8461 atttggttaa aatctataag actatattaa aatagtacag aatattcaaa actgtgtata
     8521 atgttcgtat tttataaaaa ggaagtgaat gtatggttaa gactaatgct atgagaatat
     8581 tagattcaaa taagattgat tataaagtaa tgtcttatga agtgaaaagt gaacatgtgg
     8641 atggtgttga ggtggcacat gatataggaa gagatgtaaa tgaagtgtat aagacattag
     8701 taactcaagg agttagtaag aatatatatg tatatgtaat accagtacat gaaaacttag
     8761 acttaaaaaa ggctgcaaaa gtagctaaag agaaaagtgt agagatgatt catgtaaaag
     8821 atataaataa gcttacaggt tatattagag gcggatgttc tcctataggt atgaaaaagc
     8881 tttataaaac ttttgtaaat gaaagtgcaa agaatttaga tacaattatt gtgagtgcag
     8941 gaaaaatagg atatcaaata gaactatctc catttgattt acaaagactt ataaaagtag
     9001 aatttgtaga tgtaataaaa aaataagaat tacatataaa atatagagct tatattctta
     9061 ataataggtg ttgtaatatt aataaaatga ataataattt taaaataaat attcagttac
     9121 ttatgtgtaa ttggtataaa aatattgaga aattttaaaa acaatggtaa agtgtaagta
     9181 taatcacgaa tattttttat aaagtaatgg agggatgttc gcttgagaaa aataaaatct
     9241 gaacaaatcg tcgagcaggt aaaaaaactt tgtatagaag cgagcctata tttaggagaa
     9301 gatgttttaa gttgtataaa agaaaaagcg aaaagcgaaa agagtgaagt tggaaaaaat
     9361 atattgaata tattagttga aaatgctgaa atagctaaag aaaaaaatat accaatatgc
     9421 caagatactg gtatggctgt attttttgtt gaaataggac aagaagtttt aattgaagga
     9481 gacacactta ctgatgctat aaatgaggga gtaagacaag ggtatgaaga aggctactta
     9541 agaaaatctg ttgtaagtcc aattaacaga gtaaatacaa aagataatac acctgctgtt
     9601 attcattatg atatggtaaa aggtgataaa attaaaatag aatttgcagc taagggattt
     9661 ggaagcgaaa atatgagtaa gatgaaaatg ttaaagccat cagatggatt ggaaggaatt
     9721 aaaaaattca taatagatac agtttcagaa gctggaccta acccatgccc tcctatggta
     9781 attggagttg gtataggtgg gactgtggac aaatgtgctc aaatagctaa aaaggcactt
     9841 tttagagaac taggtgaatt taataaggac gaaaatatag caaaacttga aagtgaacta
     9901 ttaacagcta ttaataaact tggtatagga cctcaaggct taggtggtac tacaacagct
     9961 ttgggattaa acatagagac ttttcctaca cacatagcag gtctacctgt tgttgtaaat
    10021 ataaactgcc atgcatcaag acataagaag gtagtaattt aggaggaaaa taaaatgata
    10081 aaaataacta cacctgtaaa tgaaattgat atagcaaaat taaattgtgg agatacaatt
    10141 agtttgagtg gtatacttta tacagcaaga gatgctgctc ataaaagatt gatagattgt
    10201 ataaataaag gtgaagaatt accatttgac gtatatggtc aaggaatata ttatgtagga
    10261 cctactccta caaagccagg agaagttata ggtgctgcag gtccaacgac gagttataga
    10321 atggatgatt tgactatacc tcttttagaa agaggtctta gattgatgat aggcaaggga
    10381 aaaagaagtg atgaagttat agaaggtatg caaaaatacg gagcagttta tcttgctgca
    10441 ataggaggag ctggagcgta tatttcaaat tcaataaaat catgtgaaat tattgcatat
    10501 gaagatttag gagctgaagc tataagaaag attgtagtag aagaccttaa acttacagta
    10561 gcaatagata gctatggaaa taatatatat gagcaaggtc gagcaattta tgaatgtaaa
    10621 taatgtttag aaataaatat gaatatcaaa attaaaaata gttgtgtata ttttaaggag
    10681 gaaaattgat gtctaaggat tatgcaaaat tggcattaga aatgcatgaa atcaacaaag
    10741 ggaaagtaag tgtagaaagc aaggtagaag ttaaaactaa ggatgattta tcaacagcat
    10801 atacaccagg ggttgctgaa ccttgtttaa aaatacatga aaatcaagat gatgtttata
    10861 tatacacttc taaagggaat ctagtagcag tagttagtga tggaagtgct gtacttggat
    10921 taggtaacat tggtgctgaa gcatctatac ctgttatgga aggtaaagct atattattta
    10981 aacaatttgc agatgtagac gcttttccaa tatgtttaaa gactaatgat gtagatgaga
    11041 tagttaaatc tgtagagttg atggagcctg tatttggagg tataaatttg gaagacatat
    11101 cttctccaag atgttttgag atagaagaga gattaaaaaa atctttaagt atacctgttt
    11161 ttcatgatga ccaacatggg acagcaataa tagttgcagc agccataata aactcaataa
    11221 agttaattga aaataaaaaa atagaagatt tagaaatagt tataaacgga gcaggagctg
    11281 ctggtatagc catagcaaag atactactta atatgaatgt taaaaatata atcttatgtg
    11341 atagaagtgg agcattggaa gctagtatag aaaatctaaa ctatgttcaa aaagaaatgt
    11401 taaaagtaac aaatataaga aatgaaaaag gacctttaaa agatattata aaaggaaaag
    11461 atgtatttat tggtgtttca ggtccaggag ctgttacaaa ggaaatggtt gaaagtatgt
    11521 ctgagaagcc aataatattg gcaatggcaa atcctactcc agagataatg ccagaagaag
    11581 caaaattagg tggagcattt ataatgggaa caggtcgttc agacttccct aatcaagtca
    11641 ataatgtact ggcttttcct ggaatattta gaggagcatt agatgttaag gctaaagaga
    11701 taaatgaaga aatgaagata gctgctgcat atgcaattgc taatacaata agtgatgaag
    11761 aaatatgccc agagtatata ttaccagatg tatttaataa gaatgtagta aaaaatgttg
    11821 ctaaggcagt taaagaagca gcgataaaaa ctaaagtaaa tagaatataa atttttataa
    11881 cttattaaaa actagaaaag tataaaagac tagtgaaatt atgtacagtg ggatgatttt
    11941 attagtcttt ttattttaaa tatgacacaa taatgtcata ttaagcttga tataatttta
    12001 atatggttag gagccaaaga aaaatataag gagtgattta aaatggaaga aactaaattt
    12061 tgccaatgct gtgcaatgcc aatgggacaa actgatgaat tatatgggac aaataaagat
    12121 ggaagtaaaa gtactgatta ttgtagttat tgttttaaag atggtgagtt tacagctgat
    12181 ataagtatgg aagagatgat agaagtttgt atccctcata tgcttcaaag taataaggat
    12241 atgactgaag atgaagcaag aacaatgatg aacaatttct ttccaacatt aaaacgctgg
    12301 aaataatttt atgcaaaatt agttatatgc aaaacatgaa atatggtgtt gagaataagg
    12361 ggtggtgtgc tttatagcat accacctgtt ttgttacttg ctagttcagt tattcttgta
    12421 tgcttaaata tgttctcatc tctctttcta ttttaaattg taaaaatcta aaatatgtta
    12481 tttatattct acttctttat ccatgtcttt ttctacctca agtcaaatac aactacaaaa
    12541 tcatcatttt caattcactg tttaatagaa ttaacagata aagagttata aaattttcta
    12601 ttttttatat aaaataatac aggtcaagct gacttctagc tacttgggat agtgtatata
    12661 tttatgatag ttataggagt aataccaatc attagactgt tgatttgtgt agtcttttgt
    12721 aaaaacattt gttttaatat attgagtttt tgaaaaagta aaattataat tataataaat
    12781 taagtgtaat aatgtattag aagtaaaaat aattaaaata gaggtgatta aatgagcagt
    12841 atattgttag ttgaagatga tttaagcttg atatatggat tagagttctc tatacaaaaa
    12901 agtggattta gtatagacat agcaaggaca gtaaaagaag ctatgcaaat gtatgaggaa
    12961 aaaaattatg acttattgct tttagatgta tccctacctg atggtaatgg atttcagatt
    13021 tgcgaaaaag tacgagaggt ttctaatata cccattatat ttttgactgc ttcagatgaa
    13081 gaggtaaatg tagtgatggg tcttgatatg ggtggcgacg attatataac aaaacctttt
    13141 aaattaaatg aattaatttc aagaataaaa gcattactta gacgttataa tgttgcaagt
    13201 aatgtgaatg aattaagttc aaataatatt actattaaat tacttgaaaa tcgtgttttt
    13261 aaaggtgaat ttgaggtgga acttactaca gcagaatata aattattgtg cttatttatg
    13321 aaaaataaaa atattgtact tactagaaaa aacatattgg acaagttatg ggatggaaat
    13381 ggtagcttta tagatgacaa tacattatca gtatatgtaa gacgattgag aaataaaatt
    13441 gaagataatc ctgaaaatcc taagtttcta ttgaccgtta gaagaatggg ttataagtgg
    13501 aatgtaatta agtgagggta ttaatatgaa gatattttct aataaagata taaaaatatt
    13561 ttttttaatt cttatatcta ttttagtaat gtttattata gtagggcaaa tagtggttat
    13621 aagtataact aacaattata aaaaaacgtt gatagaacat gattataata tagctggata
    13681 cttatatagt ataggtgttg ataaatctaa aataccatca gcatttgttg cacatgaaga
    13741 taaatatatt ttaaaaggaa aagaaatact agatacagct ggatatggat ttgatataga
    13801 tgttagcttt acaccaagtg taaaattgtt tcaaagtaaa tatataaaaa ctatgtctat
    13861 ctatttatta gtatttttta ctatgattat tttcatacta tatatgtatt tttttaggca
    13921 acaaagtaag atagaagagg ctagttataa aattgattta tttatgaatg gaaatataaa
    13981 tgaaagacta aatacatatg aagaaggtag cttatcaaaa ttatttagtt caatagatgt
    14041 tatgtcgaca tctttaaata cacatatatt aaaagaaaaa cagagcagag aatttcttaa
    14101 aaatacaatt tcggatatat cgcatcaatt aaaaactcca cttacagctt taataatgta
    14161 caatcagata ctacaagaag aaagtcataa tagtgatgtc gttgaagctt ttgtacaaaa
    14221 aagtcaaagt gaactagaac gcattgaaac attgattaag aatttactaa agattacaaa
    14281 gatagattca aaaacaatag ttctcaataa aaataatgtt aatcttaaaa atttaattgt
    14341 caaaattttg tatagctttg aaactagggc agaaaaagaa ggaaaggtta tttctataaa
    14401 tggttcagaa aatacattgt tgttctgcga ttatgaatgg atgtcagagg ctttaagtaa
    14461 tcttataaag aatgcattag ataatacaaa agagaatgat aaaataacga tagagtggtt
    14521 tgagacgact ataaccacca ttgtttcagt taaagacact ggaaatggaa tccatgttga
    14581 ggatattcat catatattta aaaggtttta tagaagtaag ttttcaaaag ataatcaagg
    14641 tttaggactg ggattaccac tagttaaatc tattgtggaa caacataatg gtactatttc
    14701 tgtagaaagt aaactatcac aaggaagtac attcaccata agttttttaa agcttactaa
    14761 tatgtaagat aaaatacatc ttgcagtaag gtatatagat tattattata ttaatcaatt
    14821 agaaaggtga gagagaaaat ggatattctt gtggttaata atttatgtaa aacatatgga
    14881 aatggatata caaaagtaga ggcattgaaa gatgtatcct ttacagtttc aaaaggagag
    14941 tttgtgactg tagttggaga atctggttca ggaaagagta cactattaaa tctcttagga
    15001 ggtcttgata ctccaacatc agggagaata tttattgatg gtaaagaaat atgttcaatg
    15061 aaagaggaaa aacagactat ttttagacgt cgtaacatag ggtttatatt tcaggcatat
    15121 aaccttatac cagaactaac tgtggagcaa aatataatat tcccattgtt attagattat
    15181 aaaaaaccag atactattta cttagatgaa gtattgacta ttttaggtct taaagatagg
    15241 aaaaatcatc ttccaaatca attatctggt ggtcaacaac agagagttgc aattggaagg
    15301 gctttgatta caaagccaag tattatactg gcagatgagc caacgggaaa tcttgacagt
    15361 aaaaatagta atgatgtaat ttcactttta aaagtgactg cagaaaagta taatcaaacc
    15421 attattatga taactcataa tacgaatata gcttctacag cagatagaat actacaggtt
    15481 tctgatggtg tgcttacaga cctgggggtg aatagagaat gagaagctac ttagaattag
    15541 taccacaata tgcaaaagta cataagaaaa aaaatagaac tacaatttta tgtattatta
    15601 ttgcagtatg cttagttact gctatctttg gacttgcaga tatggctata caatgtcaaa
    15661 agatacaatt tattaaagat gatggaaatt ggcacatagt aattagaaat attgatgaaa
    15721 agtttatatc agaaataaat agtagagtag atatagctca ccatggtagg gggcaagtcg
    15781 ttgacagtgg agagtttaaa tcaaaggaga ttttgataca aggtttagat gaagaagtag
    15841 caaaacaatt taacttagaa ataataaggg gtcgttatcc tattggggag aatgagactt
    15901 taatagatga ggatgcagtt aaaagcttta atctaaaaat aggagatttt atcaaaataa
    15961 aattagcaga tggtagaaat aaaaattata agatagtagg tgaatattca tcaatatcaa
    16021 gcttaagagc tacagataaa catggattaa tactttcaat attgggtaca caagctatta
    16081 aaaaatcaga aacgtacgat tattattata ttacatttaa agaaaaggtt aatattagaa
    16141 aagccacttc tgatattaaa aataccttca atttaagtga taaacaaatc ggtaaaaatg
    16201 aaagattact ttctattata ggtcaaggcg actctgactt ttctaaacca ctgtatttaa
    16261 cagcaggatt actttttgta cttgttttag tagcaagtat tatcatgata tataatagtt
    16321 ttaacatgag tgtaattgag agagttaaat tttttggtct gttacgttgt ctagggtcat
    16381 caaaacatca agttaaaaaa tttgttgttt tagaaagttt aattttaagt ataaaagcta
    16441 ttccaatagg cttagtatta ggaagtcttg taactattat atcttctata tttcttaagt
    16501 atgttaatga gttattcagc tcaatgccaa ttttaaaagt tagttttatt ggtattgcat
    16561 ttggaataat tgtagggttt ttaactgtaa tattatcagc tattattcca gcaaaaaaag
    16621 cttcccgtgt atctccactt agcgctgtac gtgggaatct aatgtccaaa gaaattttaa
    16681 ataacgggaa gacaagtaaa gttgcaaata caggaagttt taaaattgag acttctatgg
    16741 gattaaatca tgctttttca agaaagaaat cttttgtact tatgacttct tcatttgcca
    16801 ttagtattat actattttta ggttttagtg tgcttataga ccttatgtat caaggactta
    16861 agcctatgaa gccagaagct cctcatatat ctattgttga ccctaatttt aagtctgttt
    16921 taactaagga agatattaat gaaataagca atatcaaagg agtaaagaaa gtatacagta
    16981 gaatgatgac ggatatagaa gctacatata atgggaagaa gacaaaatca caattaattt
    17041 cttatgaaaa gtatcaattt aattgggcaa aaaaatatct attaaaagga gaagttaatg
    17101 aaaataaact acagtcagaa aaccttgcat tagtagaaga ggggcatgga tttgatatag
    17161 gagataagat atatattaaa aatagaaatg ctgaaaaaga gttagaggta ggaggtatac
    17221 tttcctcaat tccatttgag gctaaagata aatatattgg aaatattata acatctgaaa
    17281 atacttttac gaatataaca ggtataaagg gttatataat aatggatatt caggttgata
    17341 aagatactcc tggagattta attgaaaata taagacgtgt agtagatgat aacttagagg
    17401 tcagagataa aagacaaagt aacttagagg ttaaaaattc gttttatact atggcaacat
    17461 ttgtatatgg atttgtgttt attattgcga ttataagcat gtttaatatc ataaatagca
    17521 tgaatataag tgttacaagt agaaagaatt actatggtgt tatgcgtgca gtaggcatat
    17581 ccaacagaca attaagaaga atggtaatag tagaggcagg ttcatatgca atgagtggtt
    17641 gtttattagg tagtatacta ggattaatgt tacataggta tatgtttata tcgttagtaa
    17701 gttcaatgtt tcatttagag tggcaagtac cttttaattt actacttatc actgtactaa
    17761 ctatgataat aataacttta ttatcagtaa gaaaaccagt caaaaagatt tgtgaattag
    17821 atataataga ctcaataaat gcacaataaa tatagctgtt gatttaaatt aaaaaaacga
    17881 agtaaaaatg aaatagaaaa tatttttcat ttttacttcg ttttttatat tataaaattt
    17941 ttgttatgtt acaaaatttc tataaagatg atgtgaatct aaacattata tgacaacgtg
    18001 agcatttaag ttaaaatatt ttaaatatac tattttagat aagttccttc ttcatcttga
    18061 taaattaatc cttttttcat aagcactcca agagctcgtt taaaattttt cttacttgaa
    18121 ttaaataata tagaaatatc tttagggtca gatttatcat taaatctcat atatccatca
    18181 gaaccctcta aataacttaa aatcttattt tctaaagtat caagttcatc ctttctattt
    18241 cctctaggag aaagaccaag ttttccatct tcatatattt ttatgacatg taaattttca
    18301 agaacatcac cagcttttag ttcagtaaag tactcattat gaagtattac accagcatat
    18361 ttattgtcta cacatatcat tgcagaatta ttagtttgaa atccatatac aactccagtt
    18421 acaatatctc ctacattgta agtatggtct gttaataaat atgaatctat atctgtagta
    18481 gcagcaattc ttttgctttt gtctaaatat atataaaata aatatttttc gtctctaaat
    18541 agtggataag tcttagcttt aaaaggaact agtatgtctt taggaagtcc catatctata
    18601 aaagtaccaa tgtccgtatt atcaactact tttaaatgtg ctacatcccc aaccttagct
    18661 aaaggcggta ttaaagttgc agcagttctg tcatcagaat ctttaaatat gaaagcattt
    18721 acttcatcac ctatgtttat ttcatttttt ccgattaatc tattatgaag aagtatatcg
    18781 tcttttgtgt tattagtttg tccatccaaa aaatatccaa attcagtttt tctttttact
    18841 gtaagtttat taaaatcacc tatgtttatc aaattaaaat catcctctca ttttatattt
    18901 ataatttagc cataatatac ttatgtagta gtttgtcaca gtatctatat tagtattagt
    18961 gaaatttaca ataaataata tagttattta tgtatttttc aattctctag cttcttatat
    19021 agtataaact ccaatttctt ttttgtcttt aggttttact aaaattttta caaaataagt
    19081 taaaaagtat tgaaataaaa tttcttttaa agtataattg gtatatacca aaattggtat
    19141 ataccatatc gaaaagtggt gactatatga aaatagtaaa taaatctagt aatataccat
    19201 tgcatactca attaagttca ataataagag agatgataga aactggtgag cttaaagagg
    19261 gtgatgcaat aatgccagaa agagaacttt gcaacataca aaatgtaagt cgtatgacag
    19321 taaataaaac cattgttgga ttagtcacag aaggacttct ttatagggta caaggtaaag
    19381 ggacattcgt tgcaaagcaa aaaaagaagt atcagttttc aaatgtaaaa ggttttactg
    19441 atgttatgaa agaaaaggga gtaaacataa aaacggatat attatccttt gagatggaac
    19501 taccagatga tttagttaaa agaaagcttg gaataagtga taatactaca aatatatata
    19561 agattgtcag acttagatat actgatggag agccatttgg attagaaata gtatatctat
    19621 cagaagaaat gtgtaaaggt ctaacaaaag ggatattgga taattcttca ttatataggg
    19681 ttttaaatga aaaatatggc tataagatac aaaaagctga acaagtaatg gagccagtaa
    19741 tactttcaga tgaagaaagt aagcttcttg aaacagatga aggtgcttta gctcttaaac
    19801 ttcatagaaa ttcctataat agagaaggta gccctataga atataccata tcaatattta
    19861 gaacagataa atatcaatat gaaatagtat tgagtgagta ggtgaataat atgaaatgtt
    19921 taattaatgg aaagataata ttaaaaaatc aaatcttgga aaataaagta ttagtatttg
    19981 atgaaaaaat aattgatata gctgatagtg taccaaaaga ttgtgaagtt atagatgctg
    20041 atggaaaata tatatctcca gggcttattg atattcatat acatggaaat atgggaaaag
    20101 atacaatgga ttcgactgat gaatctattg aaacaatttc aaaatcaatt atgagacatg
    20161 gagtaacatc ttttcttcca actacaatga ctatggataa agaacatgtt tatgatgcac
    20221 ttgaagttat taaaaaagcc caaaatagaa agcttgaagg ggcacaagta ttaggagcac
    20281 atttagaagg accttttata aatgagaatt ataagggagc acaaaatgaa aaatttataa
    20341 taaattcaaa atacgaattt ataaaagaat ataaagatgt tataaaagtt ataacttatg
    20401 ctccagaaaa agatattgat tttgatttta ctagagaaat aaaaagatgt acagatatag
    20461 ttttatctat tggtcatagt aatgcaaatt atgaccaagc taaagaagct ataaatttag
    20521 gagtaactaa tataactcac atgttcaatg caatgactgg tttaaaccat agagacccag
    20581 gcgttgttgg tgcagcactt acaactaatg tgtacagtga gctaatagca gatacaatcc
    20641 atataaataa agatttattt caatttatac taaataataa agggaaagaa agactgattt
    20701 taataacaga ttctatagaa gctggtggtc ttgaagatgg caattattct cttggaggtc
    20761 agaaagtcat agttaagggt aatgaagcta gacttgaaaa tggagcatta gctggaagtg
    20821 tgttgtcttt aaataaaatg gtatttaact tcttagataa tacaaacctt aaagtgaatg
    20881 aagcaattaa tttagcttct ttaaatccag caacatcttt gggaataaat gacaaaaaag
    20941 gaagcttaga aataggtaag gatgcagata tagctgtatt tgatgagaat ttagattgta
    21001 aaatgacact ttgcttgggg gacgtagtat ataaaaatat atagtataca aaacaaactt
    21061 taaagacagt aaaaacaata taaaaaataa taaattaaac ttacattagt taaagtagta
    21121 gttaaaattt aggaggaata agatgagagt attagtgtgt aaagattatg atggaatgag
    21181 taaaaaagcc gctgaaatga tagcagctca aatagtttta aaaccaaatt caatactggg
    21241 actagctaca ggaagtacac cagtaggtat gtatagagat ttagtaaaaa aatacaatga
    21301 taatatagta gatttttcag atgtgatgag ctttaattta gatgaatatt ataagttacc
    21361 aatatctaat gaccaaagct atgattattt tatgaaagag aatctattta atcatgtaaa
    21421 cataaagcta gaaaatactc atctaccaaa tggaatggct gatgatattg aaaaagagtg
    21481 tctgaactat gaagcttcta tagatgcagc tggtggtata gatgtacaag tacttggaat
    21541 aggtcgtaat gctcatatag gttttaatga acctgatact aaatttgcaa aaagaactca
    21601 tgtagttgaa cttacagagt ctacaataga agctaatgca agattcttta aatcaagaga
    21661 agatgttcct aaaaaagctg taagtatggg aataggttca atattgaagt ctaagaaaat
    21721 attgctttta gcttcaggag aagaaaaagc tgatgcagta tataatactg tttacggaga
    21781 tataactcca gaagttcctg gttctatact tcaacttcat aaagacacta tagttatagt
    21841 agatgaagca gcagcaagta aactgaatcc aaaagattat aaattagtat aagaatagaa
    21901 tgtagtttaa gtgaaaaata gctatcattg aataatcaaa tttatttaat gatagctatt
    21961 tttatttaaa ttttttactt ctttttattt aaattagtta ttattgttta aattacttgc
    22021 ttattacttt ttacgaaaac tcgttatcaa gaagtatccg aataagatgt taaaaattat
    22081 tatgtttagt gggattctat caagcataat aaaattacct ataattggga tattaccaat
    22141 tggaaacata aagaagaata caggcatcag tgatagtaaa aaagatggaa aacaaagaag
    22201 aagtaatctt ggaatatcaa tataccaact accatccttt ttgtattctc taatcaataa
    22261 ttcagttcct agtaacaaac caataccacc agaggaaatt aaattaataa aaatgtatct
    22321 tttaaagtct tgcatataac cagtgtgaaa ttgagtatag aaatcataat ttaatttaac
    22381 ggctaaaaaa tatataagca atagaatgat taaaaataaa agatatctaa gagctttttt
    22441 cattttaaat tctcccttca gaaatacttt attcagtttt attttgttgg aatctgattt
    22501 tatcatttag tttaagaaat ccataatatt agtgaagaat gaaataagta ttatatatga
    22561 ataaatattt ttagaattaa ggtgaactgt agtgcttaat ataactataa tattaattgt
    22621 ttgaatattc aataaaaagt ttaaaaaata tcaattttga tataaactga ataaatacag
    22681 ttgaatatta aattattatt ttatcaaaaa tatgcaaagt actacacctt caaatatcac
    22741 ctaaagtaat taaaaggcaa ttaaagtgaa gtagttcaag tatttctaaa atgagtttaa
    22801 taaattctat aataatttat tttttgcctt aaaattgcct taaaatccaa acaattttaa
    22861 aactaatgta ctataaaaag ctggtataat ttaaatatag taaaaaataa gatttatctt
    22921 atctattggg atttaattat ttaatcaata tatttatacc atttaattta aataaaaagt
    22981 ctattaagga gtgagcttat gagtaagtta atttatatag cagatgatga agataatata
    23041 agaaatttgg taaagacatt cttaaaaaat gaaggtcatg atgttatgga ttttaaaacg
    23101 ggtgatgaac ttttagaaca atttaatata aaggagtgtg acttagtaat actagatata
    23161 atgatgcctg gctcaagtgg ttttgaagta tgtacaaaac ttcgtgagaa aagtacagtc
    23221 ccaataatca tgcttactgc aagagataca gatatagatt atattacagg gataacctta
    23281 ggtagtgatg attattttac aaaaccattt agcccaatgt ctttggttat gagagtaaaa
    23341 tctatattta gaaggataga gtttgaaaag aaacaaaatt atgataaata tagtaactcg
    23401 atagatatgg aattaaaatt tggtgatgta ataataaata aaaagaataa aatcgttaca
    23461 agtaaaaatg taaatataga ccttacacca aatgaatata atctattgac ttatttgttt
    23521 gaaaatatag atagagcagt ttccagagat gaattattaa acaaaatatg gggatacgat
    23581 atagaagttg agacaagggc tgctgatgat acagtgaaga gattacgtaa aaaaatttta
    23641 gatacaaata ttttaataga aactgtatgg gggtttggat ttaggttgaa ggagaaaagt
    23701 taagatgaat aatggaaatg acaagaatag aattggaaag attaaatcca aatttaaatt
    23761 aaagttctca aagaaaaata taagcataaa aactaggatt ttgttgagca tactttgttt
    23821 gataattata gtatttatga taatattagt atcttttaat gtatttcttg atacatatat
    23881 aaaaacaact gcgaatgaag aattgacgaa gtctacagaa atagtagaac atatggatag
    23941 taattttaga cctattaagc caccacaaga tgatggaaag cttcctccca aagtattatc
    24001 taattttatg agaaatgtac aagataaagt taggatggca gaaacacaat cagatgctga
    24061 tgctatggta gttgattcta agtataacct gatatttcca acaagagagg atgatttctt
    24121 aaaaaatgtt gatgagatgg agctgattag ggagtgtatt caaaatgaaa aattagattt
    24181 aaattcagat gaaaatacac ggatatctac cagaaataag gattattata tttcaactgt
    24241 aaaaattact agtatatatg gtgaacaaga caaatatctt atacttttta tagacatatc
    24301 aaaaactcta aatctagcac aaaagataaa tattgtatta atatctgtaa tgtgttttgc
    24361 tggaatatta gcaatattta cagctgtgat tttatctgag aaaattgcta aaccgataaa
    24421 agagttgtgt gagtttgcaa aaaaaatggg tcaaggagat ttcaaaagaa cctactttga
    24481 cttttcagat aaagaattag tagagctctc aactgttatg aataagagtg ctgagtatct
    24541 ggataagtat gataatgaac aaaaaatatt ttttcaaaat gcatctcatg aattaaggac
    24601 accactcatg tctattaaag gttatgcaga agctataaaa tataatgtta tagatagtaa
    24661 acatgcaagt gatataattc ttgaagaaag tgataggtta agtgatatgg ttgaagattt
    24721 attatacatt tctaaaatag ataatataac taaagatttt gaacttgtag aatgtgattt
    24781 aagagaagta ttttcaaatt gtggagctag gcaaaatgta agagctataa ataaggggat
    24841 aaaatttatt tatgaatttg atgaagaaat ggttttattt gaatgtgatg aaaaaaacat
    24901 ttccaaagca tttatgaatc ttatagaaaa tgctttgaga tacgctaaga gtgaaataaa
    24961 aatagtgtgt aagtataatc aaaaaaatat agttgtgata atagaagatg atggaattgg
    25021 aatcaagaaa gaagatttac ctcatgtttt tgaaagattc tataagggag tagggggaaa
    25081 tcatggaatt ggattatcaa tagttaaatc tattgtaaat aagcatggtg ggcgtatata
    25141 cgtagaaaat ggcaaaaaag gagctaagtt tactatatta tttaaattgt aaaaaaatta
    25201 gagaaaatat aaagatgttt gaagttgttt tttatatata tctgttgtat actgttgaaa
    25261 aaagaacaat attaagctga catatattac aataattgac atttaaagta aatgcttaaa
    25321 tatagatacg aaaggaaaag taaaatctga agtgtattta ggtttaagta agcttcttat
    25381 tttataaaaa atatgtatga aagaacagct gatttttaat attacaaatt tagtaacggt
    25441 tgtatttgaa gcttttgtca tccatatgtt tttatcagac tttttaggtc agaaagaagg
    25501 gtatataaaa gttgtaagat atgctaaact gggttttata atatgtttag gattctgtaa
    25561 tttaataact ttaaacccta aaatcacaat gcctttaatt tttatcctta ttttttcaac
    25621 atcattttta tataaaggaa atttaaagac acgattgttt actactgttt tattaagtat
    25681 attctttata ctgtcagaaa ttgtagttac aagtattttt gttttatttg taaaagaagg
    25741 ctttgaaata atgcttgaaa ataatagtat aagagtattg gcgacaattt tatctaaaat
    25801 tgtctttttg ttgacttgta aaattatttg tctatttaaa aaagatgtac atttagatat
    25861 gcccataaag tattggctcc ctttattttt aatacctata tttagtttat ttctgtctgt
    25921 ttctatcttt gatgtaagta aattttttag tcttgaaagt ttaaaatttc taagtttaat
    25981 atctagtgtt ggcattttat atattaattt tattgtattt tatttattta aatttattat
    26041 agataaaact aaactatcta tgaaatatga aatacttgaa aaagaaataa ttcataagga
    26101 agaattaaga cttagtaatg agtgttataa aattattgtt gaacagactg attctgtcgt
    26161 tttcgaatgg aatatcaaag aaaataaatc atttgtatcg caggcttgga ctgaaaaatt
    26221 tggatataac aatgcatgta agaatatttt taaagaaatt aaagataaag acttagttca
    26281 ttctgaagat aaagctatat ttgaaggttt tcttgaaagt attaaaaaaa agaatataca
    26341 cagtcaagca gtatatcgtt taaaaaaatc taatggtgaa tatatttggt gtagaacatc
    26401 aattacaagc atttataatg atgaaaatga acttttaaga gttgtaggag taattgtaga
    26461 cgtagatagt gatataaaaa aatatgaaga gttaagaact agagcagaaa gtgactcatt
    26521 gaccaatata tacaataaag gtacatttga aaaattagtg gaagaaacta tagttatgaa
    26581 tacaggtgat aaaaaagatg cattattcat tattgattta gatgatttta aagaaataaa
    26641 tgataatttt ggtcatccat ttggtgattt tgtactaaaa acatttgctg ataagataca
    26701 agctagtttt ggtaataaag acttagtcgg aagaattggt ggagatgaat ttgttgtata
    26761 tatgcaagat tatgttacag aagtaaattt gcataaaaaa gctaaagaat taaatagagt
    26821 actttcggat aattacactg atttgagttt tagttttgat tcttctgtca gtataggtat
    26881 tgcaaggtat cctcaagatg gaacttcatt ttttgaattg tttaaaaatg cagatagagc
    26941 actttatagc ataaaagcat caggtaaaaa ttcatattgt ttatttgaag aagaactata
    27001 tgtacagtga atttgaattt agattttatg tgagagtaag atttatatat acttgtggct
    27061 gtctgattta taaaatatgt tactttgtat atttttatat gtttcagtaa ggttaattaa
    27121 cataagcaaa ggtgtaagta aatttatatt agtttaagtt tacttacacc tttataaaaa
    27181 taaattttgt aaatttaaac agttggtttt ataaggattt ttatttattt taatatctta
    27241 gatattcctt tttgtattcc ttagagaaaa taaataatga aaggagtaca gaaaaaatta
    27301 aacatcctaa tataccactt gaattaagtc ttaaagcatt aaagtttaaa aaagcattat
    27361 ttaaatcggt atccaaaaga aaaggatgct ttgatttgct atatatggaa aaattaaaaa
    27421 tatattcata atcaaattta taaaattaat atctttccat cctaacatta catttactta
    27481 gattaattat tattataaaa ataaaaatac aaataataga ttcatttaca ttcttaaatg
    27541 attaaagctc tttacccttt aaacatgcat aacatatcgt tataattcca gtaaataaga
    27601 ctaaaatgcc cattcctaaa attgcagttt catcatctat tactccaaat gcttttaaag
    27661 taacttattt cgctttgtat aataataatt tgtctctttt tatattttaa cttctgctga
    27721 gatttgagtt agatattcgt tagaatctcg cacacttata tcatatagaa gatattcttc
    27781 ataaacaaaa tccccaatac gtaaattatt ctgattaaaa aaatttaata acttttcata
    27841 agccttgtaa atagtttcat aactaccttt atgataagca gttacataaa gtccctttgg
    27901 tttgattgat acaggatatt tcttgtactc tttattaact tttgtaaata aatatgaata
    27961 tgattcaaag tctttattaa ttatatcttc acctttaatg attgagccaa tcgtaccata
    28021 gtcactcaat tcatagttgt ccataaagtt aatacattca tataaaaaat tttcttcctc
    28081 atctcctaaa aactgttctt tatatgtaat aggtgttttg accaagtact cttcctcatg
    28141 ttcttttaaa gtaatagtat tcgcatctat attacaggca tttttagtga atgaaatagt
    28201 agattccatt agagcttgaa tattatttag tttttcaatt tcatttttaa tatcaatggt
    28261 tttcttttct aaaagctcaa ttagtaaatt aggtgttctt ttgtctatat aagctttaat
    28321 ttcttttaaa ggcattttta cttccctaag tgaagaaatt ataccaaaaa tgctaagttg
    28381 atggtatgag tagtatctat atccattttc tttctttaat tctggtgaga aaagacctat
    28441 atcatcataa tggaaaagtg tttttttatt gattccacaa atctttgcaa attctccagt
    28501 tgtaaaataa ttttttgaaa cttgactcat aattataatt cctccttgac tatcctgtta
    28561 cagtatagtt tatcatagta ttttgtaaag gagtgtgatt atatgaaaaa attaattcat
    28621 tttttaaaac catatagagt tttaattgtt gtagttttga tatttacgtt tttacaaaca
    28681 cttggaactt tgtatatacc aacacttaca gcaaatatag taaacaatgg tgtagtaaag
    28741 ggagatatag attatattgt aaaaacaggt ttaataatga tgatagtagc tggtataaca
    28801 gctttatcag ctgtgttagt ttgtaaagta tcagcaaatc tttcatctgg attttgtaga
    28861 gatattagag aagcagtatt tgtaaaatca caagatttat caataaatga ttttaataat
    28921 ataggtacag catcaatgat tactaggagt actagtgata ttactttaat aggtcagtct
    28981 gtgtttatgt ttattcaatt ggtattacca gcaccaatta taactgtttc tggtctattc
    29041 ttagcatatt ctatagataa agcaatgaca attattattg ttgtagtaat gtttttattc
    29101 atgctttcag catttttagt tggtaaaaag cttataaagt tgtttaaaat gatgcaaata
    29161 aagatggaca atatgaatag ggtattacgt gaggtagtaa ctggagtaag agttataaga
    29221 gcttttaata gggagcattt tgaaaaaaag agatttgata gaactgcaat agattattct
    29281 gaaacagcaa tttcaataaa taaagtattt gcagtactta tgcctattgt aatgttaata
    29341 atgaatttag gtatagtaag tattatttgg tttggtggga tgagagtcag taatggaaat
    29401 atggagatag gtcatataat ggcacttatt gaatattgta tcttaatttt attctattta
    29461 atcatgggag taatggtatt tatgtacata cctagagcag gtgcatgtgc agatagagta
    29521 aatcagatat tagatataga acctgaaatt gtagatggaa atggtcgtaa agatactgtc
    29581 tcagagaggg gacatttagt atttaaaaat gtaacatttt catatgcaca atcagaagaa
    29641 cctgtgttaa ataatataac atttgaagca aaatctggag aagtaactgc aattatagga
    29701 agcactggct caggcaaatc tactattgca aatataatac cacgtttttt tgaaattcaa
    29761 tctggagaaa tatctataaa tggtcaggat gttaagaaga ttcctcaaaa agaacttaga
    29821 gataagattg gatttgtgcc acaaaaagct tttttattta gtggaacaat agaagaaaat
    29881 ataaggtatg gaaaagaaga tgcaagtatt gaagaaataa agcatgctgc aagtatagct
    29941 caagctgatg aatttatttc tgatatggaa gacaagtatg actcatttgt agcacaaggt
    30001 ggaaataatt tgtcaggtgg tcaaaaacag agaatatcca ttgcaagagc gttagttaga
    30061 aagcctgaag tatatgtctt tgatgatagt ttttctgcat tagattttaa aacagataaa
    30121 agacttagaa aagcgttgaa aaatgaaatc aaagattcat cagctataat tatagcacaa
    30181 cgtataagta caatcatgga tgctaatcag attatagttt taaatgatgg aaaaattgta
    30241 ggtattggaa aacataaaga tttacttgaa aattgtgaag tttataagca aattgcggat
    30301 tcacaactta gtaaagaaga acttgcataa aatgaagaat taatctgata tttggaggtg
    30361 tatgatatga gtgaaaaaag aatagatgaa caagatatag aagtacttag ttttgaagat
    30421 ggcatgtcag cagaaaaagt taaggatgca aaaaaaacta ctaagagatt attaaaatat
    30481 atggcaaaac aaaagtttaa aatattaatt atttttattt cagtattgat aagttcagcg
    30541 cttacagttt tagcacctat ggttatggga aaagctattg accaactatt taatggaata
    30601 aaaactgcag tccaaacagg tacaaaattc agtgtgaatt ttagtactat gggggggata
    30661 gtatcaatac ttctagggtt gtacttaatt agtgcagtat ttatatatat tcaacagtat
    30721 attatgtcag gagttgcaca aaatctagtt cttagcatga gaaaagattt aagtgataaa
    30781 ctcaataaac ttcctcttaa gtactatgat tctcataaaa agggggaaac acttagtata
    30841 gtaacaaatg atttagaaaa agtagcagat agtttacaag aaggattaat gcaacttatt
    30901 acagcagtag ttacagtagt tggttctatt gtaatgatga taagtataag tgtaccactt
    30961 acaatagtat cagctataac attacttgtt tcattgggta ttactgttgt aattgcaaga
    31021 aaatcacaag aaagattctc tgaaaatcaa aaggcactag gagagttaaa tagcaatata
    31081 gaagagatat ttactggtca aatagtggtt aaagcattta gtaaagaaaa ggatactata
    31141 agaaacttta aaatattaaa tcaaaatctt tataatgcaa gtagaagagc acagttttcg
    31201 tcatatgcaa tatctccaat tattagattt ataaacctaa ttggctatgt tattatagca
    31261 gttgtaggtg ggatatttgc atcaactgga gcaatgactc ttggtagtat acaagcgttt
    31321 attcaatatg taaatcaagc atcagagcct actacagaaa tatcttatat tgtaaatatg
    31381 cttcaagcag caatagcatc tgcagagaga gtttttacag ttatggatga ggtggaagag
    31441 ataaaggatg aagaatcttc aaaggttatt agcatgccta aaggtaaagt acaatttgag
    31501 catgttaaat ttggatatag tgatgatttt attcttatga aagatattaa tatcaatcta
    31561 aatgcaggag acaagattgc aattgttgga cctacaggag ctggaaagac aactcttgta
    31621 aatttactta tgagatttta tgagatacaa ggtggaagaa ttactattga tggtgttaat
    31681 ataaaagact taaagcgtgg agaacttaga actatgtttg gtatggttct tcaagataca
    31741 tggctgttta atggaagtat aaaagaaaat attgcatata gtaagtcaga tgccacaatg
    31801 gatgaaattg taagagcagc aaaatcagca agagtagacc attttataag gactttacca
    31861 caagggtatg acactatatt gactgaggat gcttctaatc tatctcaagg tcaaaagcaa
    31921 cttctaacaa ttgccagggc aatactttca gacccatcag tattgattct tgatgaagca
    31981 acatctagtg tagatactag aacagaggta gaaattcaaa aggcaatgaa taacttgatg
    32041 aagggaagaa ctagttttgt tattgcacat agattatcaa ctattcgaga tgctgattta
    32101 atattagtaa tgaaagaagg cactattatt gaacaaggaa gccataagga acttattgaa
    32161 aagaaaggat tctatgaaga actttataat agtcaatttt caagtgaata tgatgaagaa
    32221 gttgtatgat tatcaagttt taggcaacta aatgattgat aaatattaag ttaaatatag
    32281 taacatgtaa ggttatatgg aataagagta tttctctatt tcatataacc ttttttattt
    32341 atcaaaataa gataaaattt tctttctaaa ttagattgaa gaaagtattt atcaatataa
    32401 aagtaaaata atcattatta ttagtgaagt aaatattgtt tgccacatat atgccataaa
    32461 gatgcactta ttttacggag atttaacaaa gtagtgtaaa gtatactcta aatataaaat
    32521 aaatcaaata gagttaaata aattgagagg tgatataaat agtgaataaa aaattgaact
    32581 atagatttga aatgaagcac aaaataactg aagcagatgt gttagcttta aaatcaagac
    32641 tctatccaat aatgaagaaa gatgaaaatg catctaaaga tggaaaatat cttattagga
    32701 gtttatattt tgatactcct gaagataaag cacttttaga taaattaaat ggcgttgcaa
    32761 taagagaaaa gtttaggata agattttata ataataactg ctcttatata aggttagaga
    32821 aaaaaatcaa acattacaac atgacatcaa agctatcaac taatttaacc aaaaaagaag
    32881 taataaatat actaaacaat gatattgaat ttctaaaaga gtcgacaaat tgtttattaa
    32941 gagaatttta tttgaaatta aaatgtgaaa gattagaggc aaaaagcata gttgattaca
    33001 atagagaagc ttttatttat ccagttggaa atgtaagagt tacaatcgat agtgatatta
    33061 aaacttctgt aaattcgata gatttattta ataaagattt gccgactgtt tcggtaattg
    33121 atgagaatat gactgtattg gaggttaaat atgatgaatt tataccagat tttataaagg
    33181 atttaattca aattaataag actacttcta cagcagtttc aaagtatgct tcaagtagat
    33241 tatatattta agaataaagg ctatgattta tataaagata tacataaata aggttaaaaa
    33301 acaaataggt taaaaataaa taaaataaaa aataaataag ttaaaaatag gaaggatgat
    33361 tttaattatg acatttaatg atatttttaa atcaagtttt atagaaaacg tatcaggttt
    33421 ttcatttgtg gacagtgctt tagcactagg ttcagctttt ttagtaggtt tgtttatata
    33481 tatggtctat aaaaagactt atatgggaat tatgtattct cgaccattca atgtgtcgct
    33541 tgtagcactt acaatgctta caacttttgt aatattggcg gttacttcaa atgtagtttt
    33601 atccttaggt atggttggtg ctttatctat agtaagattt agaacagcaa ttaaagaccc
    33661 aatggattta gtatttctat tttggtcatt gggttcaggt atagttttag gagcaggttt
    33721 gattccctta gctgtcatgg gttcaataat tatgggattg attctaatat tcttttcaaa
    33781 taaaacaata tctgaaactc catatatatt gatggtaaat tgtaataatg aagattcaga
    33841 agatatagca actgataaaa ttaaaaaagt atttactaaa tatcaaataa aatcaaaaag
    33901 tgttacacca gaaaaaggaa tagaattagt gtttgaagta agaatgaaat atggagagac
    33961 aagtcttata aatgacttga gtcaagtaga tggagttact aatgcagttc ttgtaagcta
    34021 taatggtgac tatgtagcat agagaggagt aatcttttat gaaagataaa aaatttaccc
    34081 ttcttatctc tattatgatt atatttttat gtgctgtagt tggagtttat agtacatcta
    34141 gcaacaaaag tgttgattta tatagtgatg tatatattga aaaatatttt aacagagaca
    34201 aggttatgga agttaatata gagatagatg aaagtgactt gaaggatatg aatgaaaatg
    34261 ctataaaaga agaatttaag gttgcaaaag taactgtaga tggagataca tatggaaacg
    34321 taggtataag aactaaagga aattcaagtc ttacatctgt agcaaatagt gatagtgata
    34381 gatacagcta taagattaat tttgataagt ataatactag tcaaagtatg gaagggctta
    34441 ctcaattaaa tcttaataac tgttactctg acccatctta tatgagagag tttttaacat
    34501 atagtatttg cgaggaaatg ggattagcga ctccagaatt tgcatatgct aaagtctcta
    34561 taaatggcga atatcatggt ttgtatttgg cagtagaagg attaaaagag tcttatcttg
    34621 aaaataattt tggtaatgta actggagact tatataagtc agatgaagga agctcgttgc
    34681 aatataaagg agatgaccca gaaagttact caaacttaat cgttgaaagt gataaaaaga
    34741 cagctgattg gtctaaaatt acaaaactat taaaatcttt ggatacaggt gaagatattg
    34801 aaaaatatct tgatgtagat tctgtcctta aaaatatagc aataaataca gctttattaa
    34861 accttgatag ctatcaaggc agttttgccc ataactatta tttatatgag caagatggag
    34921 tattttctat gttaccatgg gattttaata tgtcatttgg tggatttagt ggttttggtg
    34981 gaggtagtca atctatagca attgatgaac ctacgacagg taatttagaa gacagacctc
    35041 tcatatcctc gttattaaaa aatgagacac acaaaacaaa ataccataaa tatctggaag
    35101 agatagtaac aaaataccta gattcagact atttagagaa tatgacaaca aaattgcatg
    35161 acatgatagc atcatatgta aaagaagacc caacagcatt ttatacttat gaagaatttg
    35221 aaaaaaatat aacatcttca attgaagatt ctagtgataa taagggattt ggtaataaag
    35281 ggtttgacaa caataactct aataacagtg attctaataa taattctaat agtgaaaata
    35341 agcgctctgg aaatcaaagt gataaaaaag aagttaatgc tgaattaaca tcaagcgtag
    35401 tcaaaactaa tacagataat gaaactgaaa ataaaactac aaatgatagc gaaagtaaga
    35461 ataatacaga taaagataaa agtggaaatg ataataatca aaagctagaa ggtcctaggg
    35521 gtaaaggagg taagtcaata ccaggggttt tggaagttgc agaagatatg agtaaaacta
    35581 taaaatctca attaagtgga gaaacttatt cgacaaagca aaactctggt gatgaaagtt
    35641 caagtggaat taaaggtagt gaaaagtttg atgaggatat gagtggtatg ccagaaccac
    35701 ctgagggaat ggatggtaaa atgccaccag gaatgggtaa tatggataag ggagatatga
    35761 atggtaaaaa tggcaatatg aatatggata gaaatcaaga taatccaaga gaagctggag
    35821 gttttggcaa tagaggagga ggctctgtga gtaaaacaac aacatacttc aaattaattt
    35881 taggtggagc ttcaatgata ataatgtcga ttatgttagt aggtgtatca agggtaaaga
    35941 gaagaagatt tataaagtca aaataagatt aaaattgaat ataaataatt ttaatactgt
    36001 taagtctaaa tatttactta gcagtatttt tttagaaaat aatgtgtttg attaataata
    36061 taaggtaata aattgataaa aattaaatac agcatattaa taatacataa taaagtaata
    36121 aaaaaactgt ttaagtataa taacttatat ttagacagtt tttttcattt ataaataata
    36181 taaatgaaat tgaaaacatt tgaaggatag aaattggttg gataaatgta taaattactt
    36241 caccaaaaaa taatgacaag agttgtaact aagttgtaat aaaatggtag ttatttagca
    36301 taaaataatg tatcatagaa gtatattata aaattaataa aataagattt ttgtaagaaa
    36361 actgctggct tttgatattt agagtgagta gttaaattat gtttaggagg ggtagaattt
    36421 gttgcaaaaa gtattatgga aatttttaaa gctagtagtc ggtttattta tatgttcagt
    36481 tggtatagta ttgacgataa attgtaacct tggattatct ccctgggatg tatttcatca
    36541 aggactttca aatcatatag gaataactat aggaactgct tctataattg taggctctat
    36601 agtagttatt gctgatgtcg ttcttggaga aaatgtagga tggggaactg tttttaacat
    36661 gctactaatt ggattcttta tggatttact tttatatagt aatttaattc cagaggctga
    36721 tagtttattt gtaggaataa ttatgttgat attaggattg gttcttttgt ctgttggaat
    36781 ggtattttat atgggaagtg gtttaggaag tggacctaga gatggtttga tggttgcaat
    36841 tcaaaagaaa acaggaaaat cacttaaatt aataagaggt actatagaag ttggagcatt
    36901 aatagtagga tttttattag gtggaaaagt tggtatagga actataataa gtgcatttgg
    36961 attggggtat ttcacacaaa tggtatttgg cttatttaaa ttagattgta gtaagattaa
    37021 acatagattt atagtagatg atataaaatt tatcaaagtg tatatgagtg gtgagaaaaa
    37081 agctgctgtt caaaatatag ttaagtaatt taagaataaa ttcaacgaaa tgttaagtat
    37141 tttaaattaa cattttattt agatggataa attgaatatt aaaagaatat taaaatatga
    37201 ggattgctag aacactataa aatatagatt tctagcaatt ttttatttgt tcaatgtttt
    37261 tttagtacta gaagtcttat tctctattta atgaatgaat taatttataa ttagagatac
    37321 taaactttat agatattaat ataaacacct ttaaactgtg tattttccaa agcctttaaa
    37381 atgcttgtat ttattctaaa taaaaaaata aaaaaatgtc aaaaaaactc ttgtattata
    37441 tccaaatttt atatataatt acctatgttg tttagaaatt ttaaactcaa tgtttagtaa
    37501 acaaaatgtt tagtaaaata aaacagaaac taggaggtgc aacatggata taggtgaaaa
    37561 gataaaaaga ttaagaacag aaaaacaact gacccaggaa gagctagcta atagatgtga
    37621 attgtcaaag ggatttattt ctcaattaga aaataactta acatcaccat ccatagctac
    37681 ccttatagat atacttgaaa tactaggtac aaatttaagg gaatttttta atgaaataga
    37741 tgatgaaaga atcagtttta caaaagaaga tatgtttgaa actgaagatg aagatttaaa
    37801 atataaatta aagtggttaa ttccaaattc acaaaaaaat gaaatggagc caataataat
    37861 aacattgtat ccaggaggac agtataaaga agaaaagcca catgaaggtg aagaatttgg
    37921 atatgtatta gcaggttcaa tatatgtcca tataggcgaa aagaaaaata aagtaaaaaa
    37981 aggagagagt ttttacttta gaccaaaagc aaatcactat atatcaaacg aaggcaaaac
    38041 tacagcaaaa gtgatttggg taagtacgcc accatcattt tagaatagag gtgtttaata
    38101 attggtagaa aatataatag aattaaggga tatatctaaa cattatgagg aacttactgt
    38161 tttagataat ttcaatttag atataaagaa aaatgagttt ttaacattac ttggaccaag
    38221 tggatgtgga aaaactacaa cattaaaaat aatagcagga tttgagtatg ctgatgatgg
    38281 taaagtttta tttgaaggta aggagataaa taacttgcca ccatatgaaa gacaagtaaa
    38341 cacagtattt caaaaatatg ctttatttcc acacatggat gtttatgaaa atgtagcttt
    38401 tggattaaaa attaaaaaga ctccaaaaga tgtaatagat gctaaagtaa aagaggtttt
    38461 gaaacttgtt gcactagaag gttttgaaag acgacaagtt gaatcattga gtggaggaca
    38521 acaacagaga attgcaatag caagagctct agtcaatgaa ccaaaggtat tattactaga
    38581 tgaaccactt ggagcacttg atttaaagtt aagacaagag atgcaaatag aattaaagag
    38641 aatccaaaaa aaattaggaa taacatttgt ttttgtaact catgaccaag aagaggctct
    38701 tactatgtca gatactattg ttgtaatgta taagggcaaa attcaacaaa tgggaacacc
    38761 acaagatata tacaatgaac ctaaaaattc atttgtagct aaatttatag gtgaaagtaa
    38821 catatttgat ggaattatga tagaagatta taaagttaat ttctgtaata gagattttga
    38881 gtgtgttgat aaaggattcg aaaaaaatga aaatatagaa gtagtaataa gaccagaaga
    38941 tataaaaatg gtaaagccag aagaaggaat gttaaagggg aaagttacat ctacagtgtt
    39001 taaaggagtg cattacgaga tagaattgaa tgaaaatgga agattgtgga tacttcataa
    39061 taccaaaaat gctgaggttg ggactgaact aggcatggat atatatccag aagatatcca
    39121 tataatgaga aaagagaata actaagatga aaagaaaatc ttttttagca tatccatatg
    39181 tagtttggag tgcgatattt gtaataattc ctttaatatt agtggtattt tttagtttta
    39241 caaaagaatc aggtggaggt tatgccttta cacttgagaa ttataaagaa gtaattgacc
    39301 ctatatatat gaaagttttt gggcgttcta ttcttttagc aggaggagct acattaatat
    39361 gccttatagt tggttatcca gtggcatata taatttcaaa ggctcgtgta agtagaagag
    39421 gttcattaat attattgttt attcttccta tgtggatgaa ctttctttta agaacatatg
    39481 catgggttgc tatattagga aaaaatggac ttttaaatac atttttaggt tggtttggaa
    39541 tacaaccatt agcaattttg tatactaatt ttgctatact tttaggtatg gtgtataact
    39601 ttttaccatt tatggttctt ccaatatata cagcactatc aaagatggat aatgatttga
    39661 taaacgctgc tcatgacttg ggtgcaaata atatgacagt ttttagaaaa attatatttc
    39721 ctttgagttt gccaggtgta atgtctggaa taactatggt atttatgcca gcagtcacta
    39781 cttttgcaat atcaagactg ttaggtggag gtaaaataat gctggttgga gatttgattg
    39841 aacaacagtt tacagttgtt ggagattgga actttggttc agctatatcg atatttatga
    39901 tgatagtaat attaatatct atgtctataa tgtcaaaatt tggagatgaa tctgacaaag
    39961 aaggcggtgg gttactattt taaaattaaa gaaaataact tctaatatat atttagcatt
    40021 agtattctta tttttgtatg cacccatatt tgctttggta ctattttctt tcaatgattc
    40081 aaaatcaatg gcaagatgga atggatttac atggaagtgg tatggtcaat tacttcaaaa
    40141 tgagagtata atgagtgctt tatattatac tattgtaata gctatattag cgtctgtaat
    40201 atctacaata gtaggaacta taagtgctat aggaatacat aagatgagag gtaagagtaa
    40261 gaaattaata ctaaatgtaa actatcttcc tattttaaat acagagatag ttacagcagt
    40321 agctcttatg agcctgtttg tatttgtaaa aatggaattt ggatttacaa caatgctatt
    40381 ggcacatata atgttttgtt tgccatacgt tatactttca gttttgccaa aaatgaagca
    40441 attacctgat aatatagaag atgcagctat ggacttggga gcaacaccta tatacgctct
    40501 tagaaaagta attttaccac aaataaaacc aggtatagtt tctggatttt taattgcatt
    40561 tactatgtca atagatgact ttataataag tttctttaat gctggaaatg gtgtaagcaa
    40621 tctttctata gaaatctatg gaatggctag aagaggtata aaacctgaaa taaatgcatt
    40681 atcaacaata atgtttgcag tggttctagg tttactttta ctagctaata aaaaagaatc
    40741 tatagtaagg gggattaaat aatgattaag tttaaaaaaa caatatccct tatagctgta
    40801 ggtatgatga cagttacttt atttacagga tgtaataaag caactgattc tacaaaagtt
    40861 ttaaatgtat ataatgttgg agattatata gatgagtctc ttatagataa gtttgaaaaa
    40921 gaaacaggaa tagatgttca atattcaact tatgatacta atgaaatgat gtatcaaaaa
    40981 gtaaagagtg gtagtacaca ctatgattta gtatttcctt cagactatat ggtagagaaa
    41041 atgaaaaatg aaggtctttt ggaaaaatta gattttaaga atatacctaa tatgaaatat
    41101 ttagataaga gttttttaaa tcctgtatac gacaaaacta atgaatatag tgttgcatat
    41161 atgtggggaa ctcttggaat attgtacaat aagaaagaag ttaaagaccc tatggatagc
    41221 tggaatatac tttggaatcc aaagtataag ggaaatataa tgatgtttga ctctgttaga
    41281 gatactatag ggataactct taaaaaatta ggatatagca tgaatagtgt aaatccaaaa
    41341 gaaataaatg aagctaaaaa tcttttaatg aaacaaaagg atttagtatt ggcttatgta
    41401 aatgatgaag gtaaggatag attgcttggt ggagaagtgg caatgggtat gctgtattct
    41461 ggagatgcag ttacgctaat ggagcaaaat cctgaccttg attatgctat acctaaagag
    41521 ggaactaata aatgggtaga tgctatgtgt gtacctacaa cagcacaaaa taagaaagaa
    41581 gctgagctgt ttataaactt tttattagac ccagagaatg caaaagtaaa tgctgagtac
    41641 attgggtatt caacacctaa tacaggagca ctaaaattat tagacccaga aataactcag
    41701 aatcctgttg catatccatc taaagaagta cttgataaat gtgaaacttt tgaagatatt
    41761 ggtgaaaata taaaattata tgacaaggct tggatagagt taaaatcaaa atagggtctt
    41821 gttggtttaa gtaaatttac ttaataaata cttaataaaa ctgttctttt ttagaaaatt
    41881 tattttctaa ttattgaaca gttttatttt ttgtttaggt catgttttta ttttgagttt
    41941 atttttatga gaatttaaag tacagtaagt ttcattgatt actattttta taataataac
    42001 tataaagagg ttgtctcgaa attgagataa gcctcttttt cattgttgaa atgatgaaaa
    42061 catgtttgat ttcataaaaa aagagtgatt catgagctaa agaatttgct ttgagacagt
    42121 attttttatt aagttatatt catatgcaat ttaaatagtt tattaataaa tgaaaactta
    42181 tttgtataat gattttaata ataattagaa aaaatgggca acttaataga ataattggag
    42241 gtgtaaattt ataaaaaatg aataggataa ataaaaaaat agatttatta atattggctt
    42301 tgctcgtttt tatattttta attgttggaa tagtaatact atcgattagg acagaaaata
    42361 aattgaatgt gttcataatg ttagcaataa ttttttttat aataatgtta acttatttat
    42421 caaattcagt agtggggttg ataacaagtt caataattat atttatgtat acatcctata
    42481 ttttatataa caatattact cacaatatgg atgttgaatt tatatcatat atgtggataa
    42541 tagcaacacc agtatcttca attataatgg gtaatctgaa caaaagcata aatgaattgc
    42601 aaaatacaaa taaaaaacta tctgaacagt ataaggaatt agtgactatt gatagtgaaa
    42661 ctggacttag aaatttaaag attttttata atgatgtaaa tatggagata agtaaatcta
    42721 ttagacataa tactgatttt tctcttatga tagtaaaatt accatactac ggaaacctac
    42781 agactatatt tggtgaaaac aaaactaata aaatagtaaa atatattggt tcaaatatta
    42841 tagaatgtac aagaaatgaa gatataattt atagtttaca aaaagatatg atagggatac
    42901 taatgccaaa tacatctttg gaaggttcga aagttgttaa agacagaata aagaaaagga
    42961 taaaagaatt aaatttagat ttaaacaata ggggaaaata tgtaaatata gatgtcaaaa
    43021 ttgcattttt acaatataag agtagttttg gagatagtat aaattttaag aatatagttg
    43081 aagaggaact tcaatatgat gtttaaaata tttaataaaa gtttattaaa attagtaatt
    43141 gtattatcaa tagtactgac aatatcaaat tttagcttat tttcatatgc atcagaaatt
    43201 acttccagca cagataaggt attaatcata tatgattcta agaaagaaac agcttataat
    43261 agagatattt taaatattat gagaactcta ttgggaagat ttagttcaga tatagagcta
    43321 ttaaaattga gtaactatga tggtgagata aatgaaaatt attacagtca tatatttatt
    43381 ttaggaatca atgaaaactc atataataat gataaaaaca ctaaaaactt gattagttcc
    43441 ttaaattcat ataaagtaac tatatgttgg ttaggatatg gtatagaaaa tcttttggaa
    43501 cataaaaaat acaatttaga ctatgtagga aaaacaaaca atatagttag tgtaaattat
    43561 agaggtaaat catataactt ggatgaacat tatgttttta acattgtaga atcaaaagat
    43621 acaagtaata aagtaatagg aagtattaat gataccttaa ataagtatcc atatataata
    43681 aatgataaaa atctttttta tgtatcaaaa ttagatttag atggagtttt attttatata
    43741 ttttgcgatt cacttaatga tatttttaat attaagacgt ttgataaagg acgtatattt
    43801 gtaagaatag aagatgtaca tgcttttaga gaaccaaaaa atcttgtaga gatagcggat
    43861 tatttaagta gtaagaatat accatttacg attgcattaa taccagcata tgtaaatcct
    43921 aaaaatcata aagtaataac tttatcagaa agccctgaaa ttgtcaaagc aataaaatat
    43981 atgcaagata aaggtggaac tgtgatattg catggatata ctcatcaata caagaaagaa
    44041 gaagtttctg gagaagggta tgaattttgg gatggtaaaa aagatgaacc cttaaaagaa
    44101 aatatgaaga tatttgtcaa agatagagtt ttgaatggtc ttagagtatg tatagagaat
    44161 ggaatttatc ctcttgcatt tgaagcgcca cattatgcaa tggaatcaga gggatataaa
    44221 gaattaaaaa aatatttttc tacttatatg gggcaacatc aaaataatga taaaaaattt
    44281 agcacaaata catatcctta tattattagg gatacagagg agtttaatat atttataccc
    44341 gaaaatttag gatatataga cccagaagac aagtttactt ttcaaaatat aaaagaaaat
    44401 ttagataaat tatctattgt aagaggtttt agtggagggt tcttctttca ttcatattta
    44461 aacatagagt atctaaaaaa cacaatagaa tatttagaaa aacagaatat agaatttatg
    44521 aatttaagag attttaataa ttgggtaaaa gttgatgaaa tacaaataag aaataatgga
    44581 gatgaaatta tagtcaacta tgataaggac ttagatgaaa taactaaaag tgatactaga
    44641 tttaaataca tatccaatat tagtaaaatt ttaatattca tagtatctat aagtgtttta
    44701 atatttgtga ttatatttat atattttaag agaatagata aaaagaaatt tttaaaataa
    44761 atgattttat attagaatca atattttaaa atattttagg agaaatttat gagagattta
    44821 aatgtatcag agtatttgtt cgtatttagt ctgtttagta tatggtcttt attgcttata
    44881 aatattattt tagctatggg tggatatata ttttatttta aaaactttga taaagaaata
    44941 aaagaaattg atgaatatcc tatgatatca atacttgttc ctgctcataa tgaagctaaa
    45001 gtgataggta gaactgtgga gtctttgtta ttactcaatt atcctaagag taagatggaa
    45061 cttattgtta taaatgacaa ttcttctgat aatagtaaag aaattttaga aaatataaag
    45121 gataggtaca acaattataa tttcactata ataaatacag atagtttaac aggtggaaaa
    45181 ggaaagtcta atgcattaaa tattggatat aaggtttcaa aaggagattt tatagctgtt
    45241 tatgatgcag ataacacacc agataaaaat gcacttagat atctagtaca aactatagta
    45301 atgaatgatg aattaggtgc tgttattggg aaatttagga ctcgaaataa aaataaaaac
    45361 ctattaacca aatttataaa catagaaaca ttaagctttc aatggatgtc acaagctggt
    45421 agatggcaac tttttaatct atgtacaata ccaggaacta actttatatt gaggagaagt
    45481 atcatagaag aaattgaagg atgggatagt aaagcaattg cagaagatac agaaataagt
    45541 tttaggatat ataaattggg atacaagata aagcttgtac cacaatctat aacatgggaa
    45601 caagagccag aaactgttaa ggtgtggata aagcaacgta ctagatgggc aaaagggaat
    45661 atatatgtat taatgaaata tataaaaaat atatttaaac agggaagaaa taagattgtg
    45721 tttgatatag cttacttttt ttctgtatat tttctatttt taacaactgt aattatatcc
    45781 gatattttat gtgttttaag tatatctaaa ctagtagaaa tttctattcc aattaacttt
    45841 tttctaatat ggatactatc ttatctttta tttattatag aagtgagtat aagccttact
    45901 atagaaaaag gtgaagcaac aattgaaaat atattcatag ttgcaataat gtattttaca
    45961 tactctcaac tatggctgtt tgtagctata aaagggatga tagagtatct aaaagatata
    46021 atttttaaaa gagaggttaa atggtataaa acagaaagat tttgattcat gtacaggagg
    46081 aattaacatg aaaaaattta ttatatcaat tatatcttta gtattgtttt tttcaaatat
    46141 atcacttata tacaaagtaa atgctgatga gactaaagtt aaaaattata agtttgaaag
    46201 agatataact attgatggtg ttataggaag taatagtact ttttttgaag taaataaaaa
    46261 ttgggatatt gaagaagttt tattgcatct taattttagt aagagccaaa tattaaatgg
    46321 agatgtttca agtttaactg tattgataaa taatgtacca ataaaatcta ttaaattaaa
    46381 tgctaagaca aattataaaa atacattaga agtattagtt ccaaaagatt atataattca
    46441 aggatataat gaaataaaaa taaaaacata caaaacaata tctgataaaa tttgccaaga
    46501 tgattccaat actgggaact ggatggttat tcacaaagaa tcatatatat caattagata
    46561 taagcagaaa aaggtggaaa actcaataaa tgaatatccg tatccatatg cagaaattga
    46621 aaataatcat aaattagata caactatagt agtaccagat aatatgacta gaggagagac
    46681 tacagcagtg tttaatttgg catcatcatt tggaaaaata acaaaaaatg atgatttaaa
    46741 gttagatgtt aaattatatt cagaaatgaa aaattggtca gatgataata ttatatatat
    46801 tggtaaacct gaaaatacag cagaagaaat tttggatatt ttaagtataa aggaacaaac
    46861 cctattatct tcaaactgta taatcaagca agtagattca ccatacaata agaataagaa
    46921 gatgatggtg gtaattggta gtaatgaaga tgatttaata aaggcatcaa atttattaat
    46981 agaaaataga ctttctaacc aagttttatc atcatcagtg cttgtaaaca aagagactaa
    47041 tataaaaatt aatagggaac aaaaattaaa tttaggtcat ttaacattaa aagacttagg
    47101 atattctgac tttttgttgg aaggagcatt taatcaacaa gctttgtttg atgtcaaaat
    47161 accaacgggt aaggtattag atgatggttc aaagattatc ttaaatttaa gatattctga
    47221 caatttagat tttgaaaaat ctttagttac agtgtctata aatgatgtta ttgtgggaag
    47281 taaaaaattg gataggtcac attctaataa tgataagtta gaattaaaaa tacctaaaga
    47341 tatagataat aaaaactatt atcaagttaa attgacattt aatttgagta taaaaaattc
    47401 gaattgtgtt actagagaga gtaataatcc ttgggcatat gtatcaaata attcttattt
    47461 ggcgttatct acgaaagaaa atgaaacctt atcttttgaa aattatccgt atccatttgt
    47521 tagagatgat gagtttaatg atttaactgt gataatgcca gattattcag ggtcacaagc
    47581 tatgacctgg atgtttagat taggtgttac tttaggtacg aatataaatt cacataatgg
    47641 aaatataaat gtaattagag gaaaagaatt tagtgacaag tataaggata ctaatattgt
    47701 agtttttgga gtgccacata ataattctgt tataaagatg ttaaataata atttaaatat
    47761 aaagttcgat aaaaattact ccaattttat atcaaatgat aagataagct ttattgatga
    47821 ttatggaaaa aatatttcta ccattcaatt aataaaatca ccatataata atcaaaaaaa
    47881 tatcatggta attagttcaa tgaatgaaaa aaacttatat ttaggaatgg attatttgtt
    47941 gaataaaagt aaagttaatg atttaaaagg agatacattg ataattgatg aatacggaga
    48001 ggtagaagat ttagcttata atttaaaacc taagaaagaa gtaaaagatt caagctggaa
    48061 tatgagtata aataagacaa ctaaagtatt tttaatgatt tcttttatta ctataattgt
    48121 agtcatgata ttatcaatgc tatatataaa aaaatataaa agaagataat atgataaatt
    48181 tattatttta aaagaggtat ataatttgag gaaatatatg aataaattta aattaaaaag
    48241 aagcatttta atctcattaa taatcttaat ttttatattt atagtgtact ttgtaagtat
    48301 tgagttaaaa gatgggagtc tagtaaataa tcaatataaa ggtaagatta aatcggccaa
    48361 tttatctgta gattatgaaa taaatcaagt tatgaaggat atagataaat tgggattgaa
    48421 tacagtaaat gtacctataa ttataaatgt agagtccatt aattctgata ttatgtcaat
    48481 agataataat agtaaagaaa aggcaattaa gttaataaaa aaattaaata aaaaaggtat
    48541 ttcaacaata ttagaggcat atccatgggt tgaaaatgga aaattgtatg agactgactg
    48601 gaaccctata aataaaaaaa gattttttta tacttggcaa aatgccatat taaatgaact
    48661 tataattgat gtagcaaatc cactggatgt aaatgtttta aatattggtt ctaattttgt
    48721 acatttggaa gaatatcaac aaaattgggg tgaaataata gattttgtac aatccaaatt
    48781 tgatggtctt gtaacgtaca gaactaattg gtggtataca aaaaaagatg attcaagtag
    48841 taagttgttt tatgaacaaa aattgaacaa taattttttt gataagttag attttatatc
    48901 tatagcagca tattttgagt taagtaataa acctgttaat acagtggatg aattaatttc
    48961 tgccttacac tcatctactg taaacaatag aggacaaaat ataaaacaag aaatatataa
    49021 cctttataaa gctcatagaa aacctatatt ttttggagaa ttaggttttt caaatagaga
    49081 aagtgcaagt tctcagccgt ggaatcatac tccttcaaaa gctgtaaatg gcgaagaaca
    49141 agcaaggtgt tttgaggcat ataagaaagt ttttgaaaat gaagactgga taaatggttt
    49201 ttctgtgttt tgtgtaggta aaatagatga cgaaaaaaat ttttacccat caaaagagag
    49261 tataaaagtt attaagtctt ggtatgaata attttaaaag tgtagaattt atatagatta
    49321 aatagatgat taggagagat ataaatgaat gacatcaagg ttatgactgt atttggaact
    49381 agacctgaag ctatcaaagt agcaccttta ataaaggaac ttgaaaaaag agagaatata
    49441 aaaagtattg tttgcgttac agctcaacat agagaaatgc ttgaccaagt tatagaaacc
    49501 ttcaatataa atgtagacta tgatttggat ataatggaaa aaggacaaag cctgaatgat
    49561 ataacatgta agattttaaa taaacttccc ttgattttaa acaaggaaaa tccaaatata
    49621 atattggtac atggagatac aaccacaact ctagctacaa gtttgactgc attttataat
    49681 aaagctcttg ttggtcatat agaagctggg cttagaacct atgataaata ttctcctttt
    49741 ccagaggagt taaatagaca acttacaggt attattgctg atatgcactt tgctcctact
    49801 aatttggcta gaaaaaactt gatttctgaa ggaaaaccta ataataatat atttgtaact
    49861 ggtaatactg ctattgatgc tttaaagatg acaataaaag aaaactataa tcatcctata
    49921 attgatgaga ttggtaacga taggatgatt ttgttaacct ctcacagaag agaaaatttg
    49981 ggtaaaccta tgaaaaatat attcagagct ataaagcgaa tagtagatga ttttgaagat
    50041 gtacagatag tatatcccat acatttaaat cctaaaatac gaactatagc tgatgagata
    50101 tttggaaaat ttcctgaaaa aattcatatt atagagcctt tagatgtagc tgattttcat
    50161 aactttttaa ataaatctta tatgataatg actgatagtg gaggaataca ggaagaagct
    50221 ccatcattag gtaagccagt ccttgtgttg cgtgataaaa cagaaagaac agaaggaatt
    50281 gaagcaaaga cacttaaatt agtaggtact aatgaagata gaatatataa ttcagtgagc
    50341 gatttattaa taaataaaga tagctatgtt cagatgagta aagcatctaa tccatatgga
    50401 gatggaaatg caagcaaata tatagtggat ataataatta aaaaatttaa ttgcaaatat
    50461 ttaaattaga taaggtctaa aacattaact aattgatata agatttatga taatattaag
    50521 gaatacaatt tttaaggggg agtaatatgg ctagaaaatt aataaaaaat ttaggtaaaa
    50581 gtaaaagtgt aaagagagtg aaacttttat ttaagaagat ttttattact gtattcatag
    50641 tagcaagtat agttgctatt tttaatataa cgaaatattt tgaggaatta tacaaagtaa
    50701 gggatttaaa aagtactaaa attgaatact atatggatgt ggctgatgaa gcaggagatg
    50761 gaaaggtcca attaagttgg aaggccttac ttgctataga catggtaata catgatgaag
    50821 atttaagtaa tataaaaaag aaagacacat tggatatagg ggaaaagttt atagtagaag
    50881 ataaaaatga taaaggcgaa aaggtgtata aggtaaaaaa gtttaataag gtattaagcg
    50941 aattgaaatt tgactcttct caaaaaagta gagcaagaaa atacatgaaa gatttggaat
    51001 acacatacct tggaaataaa caattagata gtagtgatga aaaaattaaa tttataaaga
    51061 agttagaaga ctcagctata agagaatata ttgattatgg aatattgccc tctgtaacaa
    51121 ttggacaagc tatattagaa tctggctggg gaaattctaa acttacaaaa cagagtaata
    51181 atttatttgg tataaaagca gataaagcat ggaaaggaaa aagtgtagaa atttcaactt
    51241 cagagcatta taatgaaaaa attgtagcta gttttaggtc gtataattca ttacaagatt
    51301 ctgtcaaaga ccacagttta tttttaatta ataataaaag atatagaaaa catgggttgt
    51361 ttgaggcaaa agattatatt agtcaagctc aagcattaga aaatgcagga tatagtacag
    51421 cagaagataa aaaaggaaat cgtatatatg cagagctatt aatagatatt attaggagtt
    51481 ataatttgca attgatagac aataaagttg agacaaaata attgttaact ttatatgagg
    51541 agataacaag ataagattct tttctacaaa aagaatagaa aaattgtaaa aaaaactaaa
    51601 aaaatgtatt gacttgttat ttaaaaggtg atattattat tactgtactc gaaagagaac
    51661 aaaa
//
LOCUS       DAMJYN010000020        50806 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.020, whole genome shotgun sequence.
ACCESSION   DAMJYN010000020 DAMJYN010000000
VERSION     DAMJYN010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 50806)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50806)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50806
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.020"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            185..388
                     /locus_tag="PC466_001270"
     CDS             185..388
                     /locus_tag="PC466_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2768663.1"
                     /translation="MISYAPLWKLLIDRKIKKMEFVNISGISISVLGRLGNDKSVSMD
                     TMEKICLALDCKIEDVVEIKKGI"
     gene            552..1706
                     /locus_tag="PC466_001271"
     CDS             552..1706
                     /locus_tag="PC466_001271"
                     /EC_number="1.1.1.267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate reductoisomerase"
                     /protein_id="HDF2768664.1"
                     /translation="MKKISILGSTGSIGKQTLDVVREHRDKFEIVAISANSNIELLLE
                     QIVEFKPKYVTVFEENKALKLKEMLPKNIEIEVLAGMEGLKIISSLDEVDVLLTAVVG
                     MIGLVPTLCAIKKGIDIALANKETLVTAGELVMKEAEKYNVNILPVDSEHSAIFQCLN
                     GENKKNIEKIILTASGGPFRGKKKGELVNITKNEALKHPNWSMGRKISIDSSTLMNKG
                     LEVIEARWLFRVEQENIDVVVHPQSIIHSMVQYADSSIIAQLGCPDMRLPIQYALTYP
                     DRMESSFERMNFSKFSTLTFEEPDLETFPCLKLAYECLKMGGTYSSVLNSANEVLVSE
                     FLEDKIGFYDIPYYIEKTLEVHSSISEPTLEEILETDRWSRAYVANLIKK"
     gene            1719..2723
                     /gene="rseP"
                     /locus_tag="PC466_001272"
     CDS             1719..2723
                     /gene="rseP"
                     /locus_tag="PC466_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HDF2768665.1"
                     /translation="MTIIAALILFSIIVLIHELGHFIFAKRSGIKVNEFSIGMGPKIY
                     SVKKDTEYSIRALPIGGYVSMEGEDEEQISPNSFGNKSILQRFSTIVAGPIFNIILAA
                     ILLVPVFLYIGSPTTKLGKIMPDTPAQAVGLQVGDKINKINGNSVKTWDEVANIINTS
                     SGGELKLSITRDGSNKVVNVTPKNNNGKYEIGIQPQREKDFLASIVNACKTTVDMTKQ
                     MLTFLGQMITGRVPGGIGNAVAGPVGVIGMVSDAARTGIINVVYLAAVISLNLGIVNL
                     LPIPALDGWRILMLLLEAVRGGKKLDPNKEGMINVVGFGALMLFMLFITYKDILRLFQ
                     "
     gene            2906..3961
                     /gene="ispG"
                     /locus_tag="PC466_001273"
                     /gene_synonym="gcpE"
     CDS             2906..3961
                     /gene="ispG"
                     /locus_tag="PC466_001273"
                     /gene_synonym="gcpE"
                     /EC_number="1.17.7.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin-dependent
                     (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase"
                     /protein_id="HDF2768666.1"
                     /translation="MSYERRKTREVSVGTVKIGGENPISIQSMTNTDTRDADATIAQI
                     KRLEEAGCDIVRVAVPDIKAAKNIAKIKSSVNIPIIADIHFDYKLALEAIEQGVDGIR
                     INPGNIGSRERVKMVVEKCKERNLKIRIGVNGGSLEKELLKKHGSATAEALVESAMGH
                     IKILEDLDFHNIVISLKSSDIYKTVDAYELISKKVDYPLHIGITESGSVHKGTIKSSI
                     GVGALLLKGIGDTVRISLTGDPVEEVIVGKQILRSLGLLNDKIKVISCPTCGRCNIDL
                     ISVVNEVEEKIGSMEKNITVAIMGCAVNGPGEAREADIGIAGGKGEGLLFKKGEIVRM
                     IDGNKLVDELLEEIEKL"
     gene            4309..5133
                     /locus_tag="PC466_001274"
     CDS             4309..5133
                     /locus_tag="PC466_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768667.1"
                     /translation="MRYKKISSLPILVVALLITGTTTTFSLSTTNSEKTNVYLASTVS
                     TVTKKVSDIQSSKGLVYNENIPLFINNSKIQYDDTPYHWPSNVISLTNSSEKAIMDYE
                     ITCLAYDKNGKPLELYWDAQNVAADGEVGSVGFSPAGVDYGIVTGISPVSPKSYSHTY
                     RKMQQSPPQDIISMFEKQQGKAWVENWLKEWKQMEKEYAKQNAIAPGKNQNDAFLLFD
                     KWKQSTGEHGVKYIISCVKQVTFNDGSIWKNSAYENWLKSFQGKEVSNSVLENYYK"
     gene            complement(5606..6729)
                     /locus_tag="PC466_001275"
                     /pseudo
     CDS             complement(5606..6729)
                     /locus_tag="PC466_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861460.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3810 domain-containing protein"
     gene            6926..7150
                     /locus_tag="PC466_001276"
     CDS             6926..7150
                     /locus_tag="PC466_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768668.1"
                     /translation="MIIKLTKDNFNFRFKQYEGMFFHAEVVEGMESIRYKITKDKEGT
                     ELKEFGSTHIKDNMIYVPQVEAYIDLNSIK"
     gene            7203..7727
                     /locus_tag="PC466_001277"
     CDS             7203..7727
                     /locus_tag="PC466_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2768669.1"
                     /translation="MSKPIDITIRPIRREDAQAFNEIRRTYSVMRNTLALMSDRVDKT
                     EAMLASLGENDYMFVAETNNNGEKDVIGFAGLHVNSSPRLRHSAEIGISVAENYQGRG
                     VGKKLMEQLLDIADNWIMLTRVGLEVIVDNEKGLNLYKKLGFEIEGTKKYAVIRDGKF
                     EDVYIMGRYNKNLI"
     gene            complement(7832..7978)
                     /locus_tag="PC466_001278"
     CDS             complement(7832..7978)
                     /locus_tag="PC466_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768670.1"
                     /translation="MDMDLLFKIVFAIVAIGVSVKIIKTVASLAFKIALILLIILFVY
                     RMFL"
     gene            complement(8117..9043)
                     /locus_tag="PC466_001279"
     CDS             complement(8117..9043)
                     /locus_tag="PC466_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HDF2768671.1"
                     /translation="MNFSNIFIQVAVLFIIILVGYFVRKFNLLDDHCTSKLSTLTMTV
                     FLPSMIISSMQINFDSKMIQKILLLLFTSLIMYIVSIIIAFLLKYILKCNDKKDLGIY
                     QYIVVFSNVAFMGYPVIEAVLGHEAIFYTAIFNLPFNLFSFTLGIYLLSKGSTSRGFS
                     IKSLISPATIAIVIGLFLFVTGLRLPQFINEPLEMLGSITTPISMIIIGSLLANSSAL
                     DCFVNKKLYIVTFIRLLVLPVIVYFILKGWINDKMILAIPVVISSMPAAANTAIMANQ
                     YDSNITLASQCVFFTTLFSVISIPFISILLLS"
     gene            9234..11105
                     /locus_tag="PC466_001280"
     CDS             9234..11105
                     /locus_tag="PC466_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sel1 repeat family protein"
                     /protein_id="HDF2768672.1"
                     /translation="MKNTKFSIKKIKNISNDPKVVHTKGALLEKMGKMESAIELYKSA
                     ALDNYVKSQYTLGNIYESKKQFKEAEKWYSMAYKSGSEDAAFDLGNMYYKLDGYEYAI
                     YWYEKIANLGYLQAQNNLGVCHFKMKDFVRCEKWLKTAADKNLGKACFNLGVLYTFLE
                     KDDEAYEYYKKGSVLLDDDAKYNLAILNGKKKDNKSTVSLYKQLYKSGHMKGCFNLGM
                     IMEINDNLEDAEKYYKKSADRDDVKSEYRLAYVYDRKEELGDAIYYYEKAIEKNHTLS
                     KYRLANLYNRENEIEKAKTYYKMAAEDDITEAKNNLAGIYFEEKDYENAIKYYEDAIA
                     VGCKSSLENLGDLYYQNQDIEKAISYYSRIPNNASCQIKLGNIYEDLNNIEEAISWYK
                     KASENGDTRSSYRLGCIYESLGNTKNARKYFEMASSKNHMNARIHLGRIYFREGKLEE
                     SKMMFDTPANENNVYAQHMVGLIYDMFYKDYVNSKFWYEKARAQGCVESIYNLGQIYL
                     KLNDDAEAEKYYKEGIKYGSKKCEYMLAGLYYKKSLDMYISLANEEYDNCEEIVEGFP
                     NLNIDFDEVLIPPFKLQEEVIDEEEYVPIYILNIKESLDSMLEGLETEMIIDEEHDS"
     gene            complement(11197..12132)
                     /locus_tag="PC466_001281"
     CDS             complement(11197..12132)
                     /locus_tag="PC466_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HDF2768673.1"
                     /translation="MIRYYKTIDSKLEKLSFFEDGCWINLVEPNHSEINEISNLLNID
                     VESIESALDEEERSRIDVEDNHTLILIDIPVDESDSNSSHYTTIPLGIILTEEAIVTV
                     CDAQTKILNDFIVGHIKDFFTFKKTRFLLQILHKNAAYYLHYLRKINKMTIIIEREIY
                     KSMKNKELVQLLELEKSLVYFSTSLKSNELVLNKMVRTAGIKKYPDDEDLLEDVIVEN
                     RQALDMAKIYGDILSRIMDAFSAIISNNQNNVMQILTVVTLIFSIPTIISGFFGMNVI
                     NMPFSNNPNGFWIILLITSIICIVITFFMSRNKLL"
     gene            12652..13164
                     /locus_tag="PC466_001282"
     CDS             12652..13164
                     /locus_tag="PC466_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HDF2768674.1"
                     /translation="MSDFKEILAEEIKNNPFGLIGKDWTLITAENEGKVNTMTASWGG
                     LGVMWGKDVAFVVIRPQRYTKEFIDNTDKFSLTFFDEDFRKELSYCGKVSGREEDKIS
                     QIGFNIEHLNDTPYFKEAKMAIICKKIYSQKLEPQCFIAEGIDGRWYPQKDYHTLYIA
                     EITNVLVKED"
     gene            complement(13319..14380)
                     /locus_tag="PC466_001283"
     CDS             complement(13319..14380)
                     /locus_tag="PC466_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015617764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitronate monooxygenase"
                     /protein_id="HDF2768675.1"
                     /translation="MIIKELIIRDLVAKVPIIQGGMGVGISRSSLAGAVAKLGGVGVI
                     SGVQIGYDEEDFETNTINANLRAIKKHISKAKEISNGGIIGINFMVAMKEYETYVKEA
                     VKAGVDLIISGAGLPNKLPSLVKGSNVKIAPIVSTAKAANVILKMWDRKEKTTADLIV
                     VEGPKAGGHLGYSNEELDNIDSIDYDKEFVEILKVANTYGEKFGRNIPVVAAGGITSS
                     SDVKKYIDMGASGVQVGTRFVATYECDAHENFKMAYINASEEDVHIVKSPVGLPGRAI
                     RNKFIEEVKINRPEIKKCYNCLIPCNPKETPYCISQALINAVKGDVENSLLFCGNDAY
                     KIDKLSTVEDVINELISEL"
     gene            complement(14504..15397)
                     /locus_tag="PC466_001284"
     CDS             complement(14504..15397)
                     /locus_tag="PC466_001284"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HDF2768676.1"
                     /translation="MLEIIVPATSANIGPGFDCLGIALNIYNKFYVEEIESGLEIEGC
                     EDAYKNENNLVYTSMKYFFDRVKPEKIPAGIKIKIHSEVPICRGLGSSASCIVAGVIA
                     ANALSGANLDKNQLLNIASEIEGHPDNVAPAILGNMIVSVTDNENIHYDIIKIPEELK
                     FCAMIPNFKLSTEKARGVLPKEIPYSDGVFNVSRVALLISALLNKNFDLLKVACQDKL
                     HQNYRGTLIENYNDIVEKSEQLNSIGVFLSGAGPTIMSLIKENDDSFVDNMKNYLQKL
                     KSDWEIKELCCDSNGAVLNII"
     gene            complement(15407..16888)
                     /locus_tag="PC466_001285"
     CDS             complement(15407..16888)
                     /locus_tag="PC466_001285"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HDF2768677.1"
                     /translation="MYYSSTRGTEEKVTASQAIIKGISSDGGLYVPSEFPNVKNELIN
                     LVNLTYSQIAFFVLSKFLCDFTEDEIKNCIENAYDEKFDCSSIAPLNKVNDTYFLELY
                     HGPTLAFKDMALTIMPHLLKTSIKKDNLEKDVVILTATSGDTGKAALEGFKDIDKIKI
                     IVFFPEDGVSPVQKLQMKTQTGKNTYVVGIKGNFDDAQSGVKKIFSDKKFNQKLLDNN
                     YILSSANSINIGRLLPQVAYYFYSYMKLVSNSEINLNDKINFVVPTGNFGNILAGYYA
                     KQMGLPINKLICASNDNNVLYDFFKTGVYDKNRTLKLTTSPSMDILISSNLERLLFEI
                     SNRNTDIVNKLLSDLSDKGVYKISDDMEKNLASFYGEYSNEEEVKSTINNVFKNYNYL
                     IDTHTAVAYNCYEKYKKETSDNTKTVIVSTASPFKFSEDVLKSIDCDFKDLDDFAIID
                     RLSSISKIDIPKPIKNLKNAEILHKDIYEKDELKLAIKKFLKV"
     misc_binding    complement(16996..17227)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            18029..18937
                     /gene="trxB"
                     /locus_tag="PC466_001286"
     CDS             18029..18937
                     /gene="trxB"
                     /locus_tag="PC466_001286"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HDF2768678.1"
                     /translation="MVDIIVIGAGPAGLTSAIYAMRAGLSVTVFEKNIYGGQVASTSE
                     VENYPAVQKISGVEFSNNIYNQAVAQGVDIQFDEVEEINLEGKVKVVKTSSGEHKAKA
                     VILANGVERRKLGCAGEQEFTGRGVSYCATCDGAFFKDKEVAIVGGGNTALEDALFLA
                     NNCTKVYLIHRRDSFRGEEVLEKSVKARENIEILYSHGVEKIEGEKTVSKIEVKNLKT
                     EEKRTIDVSGIFIAIGLKPNNKMFENVLDLDEGGYIISDESCTTSVEGVYVAGDSRTK
                     FLRQIITAASDGAIAAVQAANYINVE"
     gene            complement(19027..20850)
                     /gene="typA"
                     /locus_tag="PC466_001287"
     CDS             complement(19027..20850)
                     /gene="typA"
                     /locus_tag="PC466_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HDF2768679.1"
                     /translation="MSQKHKIINIAVIAHVDAGKSTLVDAFLSQSGVFRKNEVVKDCV
                     MDSNDLEKERGITIYSKNCAINYEDYKINIVDTPGHSDFSSEVERVMKTVDTVILLVD
                     ASEGPMPQTRFVLQKSLEFGLKPILFINKIDKKDQRAEEVVNEVFDLFVDLNATDEQC
                     EFPIIYGIAKQGIAKLEMDDDSEDLSPLFKTIVNHVEAYPNYDNEPLQFQISALAYDD
                     YVGRLGIGRIYKGTLKNNTQVAICREDSVVSKGKVSKLSVYEGLKQVEVDEATSGEIV
                     VIAGIPDISIGETICDLDSPLPMEMIKIEEPTLSMNFLVNDSPFVGKSGKFVTTRHLK
                     DRLEKELEVNVGLKVEPLDTTDGYKVSGRGELHLSILLENMRREGYEVGVSKPEVLMH
                     KEDGKLMEPIERVVVNCPEVYSGTIINELNMRKGMMESMSIEGDYVKIEFLAPTRGLL
                     GYRSEFINATRGEGTLVRSFEKFEEFKGEIPSRGNGVLIAQGPGVTMGYSLNALSDRA
                     VMFVDPGVEVYEGMIIGMNSRKDDMVVNPCKNKKMSNVRASGSDDAIKLSPPRIFTLE
                     EALEFIEDDELVEITPDSIRLRKRFLNEHDRLRYNKSRQGK"
     gene            21062..21304
                     /locus_tag="PC466_001288"
     CDS             21062..21304
                     /locus_tag="PC466_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768680.1"
                     /translation="MLEVTKIIIKYFASESDTFIKEEVCNFEELLKWSHKFIEGKKIE
                     DVLYIKSKENYKVNVIKSLEIKELEIVRKQQIPPYM"
     gene            21452..21643
                     /locus_tag="PC466_001289"
     CDS             21452..21643
                     /locus_tag="PC466_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1450 domain-containing protein"
                     /protein_id="HDF2768681.1"
                     /translation="MIRVCPNCSNVDVNKLKTLVGEENVKTGCIGQCRAFKKEAVGII
                     DNELEIKETEAEFFEACKE"
     gene            21934..24435
                     /locus_tag="PC466_001290"
     CDS             21934..24435
                     /locus_tag="PC466_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HDF2768682.1"
                     /translation="MSSNKVVESYKITGMTCAACAKAVERVTKKMDGVYDQSVNIATE
                     KLKIEYDNSKVNFDDIKQVVEKAGYGIIKEESNKKIDMKIDGMTCAACAKAVERVVKK
                     LDGVESISVNIATDKANIDYDPSKVKLSQIKAAIEKAGYKPIEEVRNKVDVDEDKLRK
                     EREMKSLFVKFIVAIVFAVPLFYIAMGPMIIKPIGPWPLPEIINPMTNTFNYALIQLI
                     LVIPVMIAGYKFYINGFKSLFSLSPNMDSLVAIGTLAAFLYSLYTTLQIANGQIQGMH
                     HHQLYYESAGIIIALILLGKYLESKSKGKTSEAIKKLMGLQPKTAIVLVDGKEVETPI
                     EEVEIGDILLVKPGTKIPVDGVVIEGYTSVDESMLTGESIPVEKNVGSKVTGASINKN
                     GVIKFKAEKIGGDTALAQIIKLVEDAQGTKAPIAKLADTVSGYFVPIVIAIAVVASLL
                     WFLIGGKDIVFVLTIFISVLVIACPCALGLATPTAIMVGTGKGAENGILIKGGEALES
                     AHKVNTVIFDKTGTITEGKPKVTDIVLNNNVKEEYLIKIASSAEKGSEHPLGEAIVKY
                     GEEKNIKFEKVDNFKAIPGAGIQVTINDESILLGNRKLMNDNNIKLGDLEEKSNVLAS
                     QGKTPMYIAVDGNLSGIIAVADVVKESSKKAIEILHDMGIKVAMVTGDNAKTANAIAN
                     QVGIDMVLAEVLPEDKSKEVEKLQNQGKFVAMVGDGINDAPALAKADIGIAIGSGTDV
                     AIESADIVLMKSDLIDVPTAIKLSHETIKNIKQNLFWAFGYNTIGIPVAAGILYVFGG
                     PLLNPMIAAAAMSLSSVSVVSNALRLKNFKAYKRD"
     gene            24595..25263
                     /locus_tag="PC466_001291"
     CDS             24595..25263
                     /locus_tag="PC466_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2768683.1"
                     /translation="MNSSILVIEDDSNIQELISEFLSAEGYQVDTANDGLEGIQKFKQ
                     GSYDLVILDIMMPNLDGYGVCKMIRKSSSVPIIFLTALNDEGDQLKGFDLECDDYITK
                     PFSFNLLIKRVEAILRRSNKTINDKFIVFEKLKLDLNTYIAEIDGEPIELTLKEFNIL
                     KALIEKYPQVITREGLLDSIWGYDYYGDTRIVDAHIKNIRKKISLPYIKTVKGIGYTL
                     EKDI"
     gene            25247..26524
                     /locus_tag="PC466_001292"
     CDS             25247..26524
                     /locus_tag="PC466_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HDF2768684.1"
                     /translation="MRRIFDKWEKLSIKYKLFSITTSLLIALALIIYLILYFLLPSYY
                     HEYKIESLQESLKSLVDSSIHFDTYTLEERLYYMAKDQNLAILLKDNQGKIVYGKNEV
                     VILRYSKYMINSLEDEYRTSIPIYTKDAKDGPYTLELVMPLQPIDEANEVIRKLMPYI
                     ISIAILIAIIGAYIYSIVITKPLINIIESEREQEYRRKDFVATISHELKTPITIISGQ
                     IEGMIYSVGKYKDRDTYLKKSYECTQELKDLVNEMIEVSKSEILEKDLKLVSINISEL
                     LNRLVKRQVFLIEEKHMKTILKIEENLEIKADQERITKAINNIINNAIKYSPEKSELI
                     IRLYDKNKRISKKTSNQRVVLEIENTGVTIEKRYLEEIFNPFYRIEKSRSRKTGGSGL
                     GLYIVSQIFKSHGFDYSIKNKENSVVFTVEFKN"
     gene            26925..27146
                     /locus_tag="PC466_001293"
     CDS             26925..27146
                     /locus_tag="PC466_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768685.1"
                     /translation="MDRLKRDMKNMKEDLKEGVKKTAYVMKNTAEDLKDDAQGAMVNL
                     EMKKDEMMERYEQKKFSKELEKQMKNEMK"
     gene            complement(27435..28199)
                     /locus_tag="PC466_001294"
     CDS             complement(27435..28199)
                     /locus_tag="PC466_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HDF2768686.1"
                     /translation="MFAEERIQAILNILKKEGRVTVKELSSKFNVTEDCIRKDLKNIE
                     KISSIRRIYGGAVLARETLENQDTKDRKEINIPTKKIIAEKAFNLIEDRETIFLDIST
                     INILLAKLLAESNKKVTLVTNMLDILNVVTSKPNNLNIISTGGLLNLSLDGFVGTPTI
                     EFISKYKFDKTFMGSCGVDVFNSSLTTFEIEDGLTKKAIINSSKKVFIVMEDKKFKFD
                     GNFKFAHLEDISSIITEKAPTPDIVDILSEFNVNVL"
     gene            28473..29147
                     /gene="fsa"
                     /locus_tag="PC466_001295"
     CDS             28473..29147
                     /gene="fsa"
                     /locus_tag="PC466_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HDF2768687.1"
                     /translation="MQLILDTGNVEEIKELCTCLPIDGVTTNPSIVSKEKKNFKQLIN
                     EIGEIIGEDMPIHAQVLSTKYEEILDEALYISSLRKNIYVKIPVTQDGLRAIKDLHRK
                     GVKITATAIFTAHQGFLAAKAGANYIAPYVNRLDNISGDGVAMVSELIKIIDTYKMDT
                     KVLAASFKNAQQVIELMQHGVHSVTVPYDICKSMMNHPLTDWSVDKFIEDWENTFGKG
                     SKTNNI"
     gene            complement(29269..30663)
                     /locus_tag="PC466_001296"
     CDS             complement(29269..30663)
                     /locus_tag="PC466_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HDF2768688.1"
                     /translation="MGIILKPKQFYMTVIVTIILYFSLNYSFNIKFSICLSFLTILIW
                     AVDSVEKTFVALFFVILAFIFNIAPIKVILQFLFTENFYIIILAYIITNAVTKTGVAK
                     IISEKLILNTVNTPKKMILLSYILGILLIFFIPQPFPRVILVSAFYKEFLKEQQITED
                     SKSILLFSIFTASTFTSMFFVNGDTLLNYVVLELGNCNINWGQWAFYMSVPTIITCFI
                     TYFLFIFVFKKELHSIKFISNENLEGNKLHFSYSNLKKEFNLLNKEQKHVFLCLGIMF
                     FMFLTQFIHNINTLIIMSICVLLLLLRKIVGFSTLKEINWKVLIFFIAAFSIGGVLKY
                     SGVVDIMGNYLIKFIPNSSEIISILFLITLTIILNICLGSAVTTSSVVIPLLGSLHIL
                     KENSVTLCLFVYIIVSIQYILPFHHATIMVGHGENLYNSKVIFKYGLTLIPLTYFIII
                     CITFPWWKFIGLEI"
     gene            complement(30741..32087)
                     /locus_tag="PC466_001297"
     CDS             complement(30741..32087)
                     /locus_tag="PC466_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF2768689.1"
                     /translation="MKDLTTGHEGKSIFFFAMPMLIGSLFQQLYNTADSIIVGRFIGK
                     EAMAAVSGANPIMFLLVAALMGVSLGFSILVSQFYGSGDLKKVKATIDTTYILLFIGS
                     ILISILGIVFGGPMLKLMNTPESVFAQSKLYLTIIFSGILFSAGYNSVSAILRGLGDS
                     VTPLYFLIIATILNIVLDLTFIVVLRMGVEGVALATIMAQAVSFIISIIYLNKKHEVL
                     KFKIKGIVYDNKIFKDGLRLGLPSGIQQMLFSIGNMTLQFLVNSYGTSAMAAFGAGLR
                     IENFISLPIMNLGSAVSTFVAQNIGAGENERVKKGIRESIKMTLVLAVTVIALILLFR
                     ENLIALFNTDKDVIKIGSSYLFIIGPFFLFIGTSFVLSSAMKGAGDSMFALISSIVSL
                     WLGRLPASYMLSKFFGTDGIWMGIPFGWTLGLIVTVIYYKKGYWKTKAIVNHRINE"
     regulatory      32337..32439
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            32533..33909
                     /locus_tag="PC466_001298"
     CDS             32533..33909
                     /locus_tag="PC466_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HDF2768690.1"
                     /translation="MQTTNSSTMQKLFPILTNKNVDMKKEIIAGVTTFLTMAYIIAVN
                     PNILSETGMPAGALVTGTCLAAAFGCILMGVVANLPFALASGMGLNAFFAYTVVLQMG
                     VPWEVALTAVFVEGIIFIVLSVSGVREAVVNAIPKNMKLAVTGGIGIFIALIGLVNSG
                     IVIGDQATLIKMGRFTPAVIITCLGLIIIAVLDKKRVKGSILFGIVVSSLLAWAFAFM
                     NPEYAQKLGIYLPGGLFKFESLAPIAGKIDLGYVLHPTNIGGFLVVVCTFLFVDFFDT
                     VGTLVGVCSKANMLDEKGNVPNVGRALLTDAVATTVGAGLGVSTVTTYVESSTGVIAG
                     GRTGWTAITVGILFLAAMFFSPVFIAIPSCATAPALIYVGYLMLGTVKDIEFDNITEG
                     VPAFVTIACMALTYSIGDGLTLGILTYVFVNIFYNIFGAKKAEDKKHVSVVMIVLAIL
                     FIIKLWLL"
     gene            complement(34023..35168)
                     /locus_tag="PC466_001299"
     CDS             complement(34023..35168)
                     /locus_tag="PC466_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HDF2768691.1"
                     /translation="MNTFEQLKISSTLIDGLKKQDITSPTEVQSLVIGNIIQNKDLLI
                     NSQTGTGKTLAYLLPIFEKIDTSKRETQALILAPTHELVMQITNQVELLAKNAELSVT
                     SLALIGEVNIQKQIKNIKAVKPHIVIGSCGRVLDLIKQKKLKSHNIKTIVLDEVDNLL
                     NGKNITCIEDIIRTTLRDRQIIGCSASLTDSTIKICDKLMKEFEIIKTKEKSQINPNI
                     NHSYLLGEIRDKFTFLRKALAATNPKKAIVFVNNEKNIEVLVSKLNYHNYKAIGIFGN
                     MEKEDRKNAINKFKLGKAKILITTDLSARGLDIVDVSHVFNLDFPKSKNEYLHRCGRT
                     SRGNRSGNTISIITKKELDIIKDLQKEFSIVITPKTLQNGELIDIIK"
     gene            35420..36127
                     /locus_tag="PC466_001300"
     CDS             35420..36127
                     /locus_tag="PC466_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2768692.1"
                     /translation="MLKVINVSKSYKNKKVVSSVSFDVNDGELFGFIGHNGAGKTTTI
                     KAIVGIHDFEEGEVLINSKSIKKQPVECKKEMAYIPDNPDLYESLTGIQYLNFIADIF
                     EVAKDKREELIKYYSNKFELNKALGDLISSYSHGMKQKLAIISALIHSPKILILDEPF
                     VGLDPKASFILKEIMREFCDKGGCIFFSTHVLEVAEKICDKIAIIKDGNIIAYGTTEE
                     VKGSNSLESIFMELIEK"
     gene            36174..37769
                     /locus_tag="PC466_001301"
     CDS             36174..37769
                     /locus_tag="PC466_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2768693.1"
                     /translation="MSNLSILIKTNIINEFKLNALKKADSREKQKIMGMILSVVIITG
                     LLIFYVTSISLSLVDILKQINQMEMLLIFGFGLSTLTTIVTSLYKTSSYLFQAKDLDL
                     LTSLPIKESTVLASKILMLVGANYLFSSICMIIPAVVYFFNSDVSITYFPYLILLFLA
                     LPLLPIVASSIIFMFIGQISSRIKYKNLILIIGSIILMLLYTLLMTRLNSMSVEMLKN
                     SVSISETIRKIYPPIYYFVDALKTGSVVSFLAFIAISIIPFFMFVTLFAKKFKDINAK
                     MSEGYKSKTYKFKSQKTSRPSKALLKKEFKRYTSSFIYFLNSSAGLLFLIIGTILILL
                     FGADKVGELLKLNIDFNFIKIQLLGVFFFIIVMNCTTYCSISLEGKNLWILKSSPIDE
                     REIFWSKILMNFLLNAPLSILCLILVSIRLGFEIQFIIVSICLIASFSMFVALMGLLS
                     NLLYPNLDWKNEMAVVKRSASMIITMLVSLAYVIILGGIYVLLGISFLNIYIILASIL
                     TFILDFMIWRIISTKGVRIFKNL"
     gene            37872..38954
                     /locus_tag="PC466_001302"
     CDS             37872..38954
                     /locus_tag="PC466_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HDF2768694.1"
                     /translation="MRKLSKREKDFIQYGFLLFLICITTYLVLTTLDIKLIPKIIRLV
                     NKTYIFLGILTIIVYMIIESIVTHLIINAVQKTKVKFIGIKMATMGFYYNLVTPFASG
                     SQPMQIYALTKYDVSLSKSVAIVTNKTVVFQSTVTVFCGILILLNKSLLMEQVHSVKV
                     LITFGMIMNVSMLLGGLLIVFSPKQVKMIAEVLINFLSKFKTFKFLDSKRDRINHYID
                     DYNYSIKIFIKNVRILVLSILLTVLQLIAYFSIVYCVYKASNLRGVSYVHIMTLQVFL
                     YMAISPIPTPGNVGANEVTFFTMFSNIIPKELLGYSVLLYSGFVYYFILIVSGLFTFG
                     THYTLNSWKKEDKVNSNLDKVIEKLN"
     gene            39103..39264
                     /locus_tag="PC466_001303"
     CDS             39103..39264
                     /locus_tag="PC466_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III"
                     /protein_id="HDF2768695.1"
                     /translation="MKQDKQNEKQSEISKIKQSNDNKLEIAQELHVSKNIGNMLGYRI
                     DKKKMNRPS"
     gene            39605..40873
                     /locus_tag="PC466_001304"
     CDS             39605..40873
                     /locus_tag="PC466_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HDF2768696.1"
                     /translation="MEASIHTIASNNLLIIFAIVSITGIICSKLSEIIKVPDVVLYLL
                     VGILIGPSFLKFIDIRGFQIENQLILTFGSAFILYLGGKEISLKVLRNVKISVFLLAT
                     LGVVISAFIMQQVIGFTFGISAMTALLAGTIIASTDPATLVPIFNQVKIKDRVKQTVI
                     SESAFNDATGAILTSAVLAVILSNKFSLGENIYELGTMVIVGVLVGLITGILLLKLVN
                     DKPYGIFKDFAPIISVISVVVAYELSTKLGGSGYMSCFIVGIITGNKKNFKIWLSQKS
                     YDADFYVAETLGTICRMAIFIILGSQVNLAQLSKYFMPSVITVLVLMFIARPLCVLVC
                     TLVDREAKWSKSEILFMMWVRETGVIPAALCGIISAMKVPGYEVISSVVFMTILITLV
                     IQGSTTKLVAKKLGLLEEEVINISEKVSTF"
     gene            41068..41856
                     /locus_tag="PC466_001305"
     CDS             41068..41856
                     /locus_tag="PC466_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD binding domain-containing protein"
                     /protein_id="HDF2768697.1"
                     /translation="MFTVMDIVQPDTVEEAYSILNKRKTNQVIGGSAFLRMGKKRIGT
                     GIELSKLNLDYIKEYEDYVEIGSMTTFRTLETSSIIKNNFGRIIEDSVKNIIGVQFRN
                     VVTVGATVFSKYGFSDLIVALLSLDTEVELYNIGRISLEEFLNRDYEKDLLIKIYIKK
                     TNKNASYKSLRNAKSDYPILNVSVSKHMEQFKLCVGARPQKATIAKQASEFLSNNEIN
                     EINIDKAVEIASEELTFGSNMRASREYRKAMSKVLLKRAIMEVI"
     gene            41856..42305
                     /locus_tag="PC466_001306"
     CDS             41856..42305
                     /locus_tag="PC466_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2Fe-2S iron-sulfur cluster binding
                     domain-containing protein"
                     /protein_id="HDF2768698.1"
                     /translation="MLVKININGKKKSVDIEPEEYLVDTLRKVGNLSVKRGCDTGCCG
                     LCTVLIDKKPTLSCATLTLRALDKEITTIEGLENEVKEFSEVLVKEGAEQCGFCSPGF
                     ILTVLAMKDELENPTDDEIKHYLTGNLCRCTGYMGQLRAIKTYLEVK"
     gene            42309..44573
                     /locus_tag="PC466_001307"
     CDS             42309..44573
                     /locus_tag="PC466_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HDF2768699.1"
                     /translation="MNIVGKGIKKIDGMSITTGKPVYTDDLSAKNALVVKILRSPHAY
                     AKIKDIDTSKAEMVDGVECVLTYKDVPKSRFTLAGQTYPEPSPYDRLILEDVVRYVGD
                     EVAIVAAIDEKTAIKAMNLIKVKYEVLTPVLDFEEAIGNKTMVHDEDRHCNFDIGMQR
                     EKNIVSHHDYTKGDVEKVLSNCDVVIEETYYTQAQAHAMMETYRAYNYLDHMGRLVVV
                     SSTQIPFHVKRHLSRALEIPASKIRVIKPRIGGGFGGKQTACVEIFSAIVTLKTGKPA
                     KIIYDRKETFNCSTSRHAMRLKVRLGATNDGIIKAIDIKALSDTGAYGEHASTTIGLV
                     GEKTLPMYNKVEATRFIADVVYTNKMPAGALRGYGASQGCFAVESTINMLANKLKMDP
                     TDLRLKNVVTEGETTFAYGKTLNSVDLIKCINKGKELIGWNEKYPCKHLDNGKIRSVG
                     MAITMQGSGIQGLDKSSAEIKLNDCGDYTLMIGSTDMGTGSDTILAQMAAEVLDTSIE
                     NITVISADTDLVPYDPGSYASSTTYVTGMAVVKAAQDLREKIISAGATKLGVEKDEVE
                     FDGIKLTSKKGSTLLFDIAVDSTIGPDTNQLIGLASHGSPVSPPPFIAGFAETEIDTE
                     TGKVDLVNYVAVVDCGTVINKNLAKIQVEGGIVQGIGMALFEEVRYTEKGSMDTNTFM
                     QYKIPARCDIGNVKVDFVETYEPTGPFGAKSVGEVVINTPLPAIQEAVFNGIGVRINT
                     LPITPEKVFMEMNK"
     gene            44713..45024
                     /locus_tag="PC466_001308"
     CDS             44713..45024
                     /locus_tag="PC466_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768700.1"
                     /translation="MAGNLNNMRAVNNFRGDKNILECLVSFEGRSISQRKVRVFFKEK
                     QNQIEIDFAEEEISKLVENVVLNTSYQEMLYDEIEKQLEIDCIGTWMILSKLKDGSRV
                     H"
     gene            45310..45810
                     /locus_tag="PC466_001309"
     CDS             45310..45810
                     /locus_tag="PC466_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HDF2768701.1"
                     /translation="MRKNSINIALTAAITAIYAVLTLSLGFISYGPIQFRVAEIMMLL
                     AFLDKGYIVGLTLGCFLANVIGPYGVPDIISGTLATFISASMIYITRKLGKQNKSTLV
                     IASLWPTVINSIVVGLMLNVFFGLPLILSMIQVGFGEFVVVTIVGVPFFCFLMKKYKN
                     VINIKF"
     gene            45867..46853
                     /locus_tag="PC466_001310"
     CDS             45867..46853
                     /locus_tag="PC466_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing protein"
                     /protein_id="HDF2768702.1"
                     /translation="MSKVKRLTDVWIYINDKQKFTIKELSEEFNLSAKTIQRYLKELN
                     KMGLPIQAEQGRNGGYRVLNNSYIPPVIFTEKEVMIILFALKSLQIYNYKLMEIEINS
                     IMRKVSYERKSSIKVGIENIKRYIGFVANDTNDGDFKSSNVTEFFRASSESLILNIKY
                     KCGNQILEKNVCPIGIYLNKGAWFSPAYDCKSDKIILVHIDNIIDIKRTGESKKIHIN
                     LEEWLHEVYNNLYGNSSTTKKFGEIIYLNVLLTKEGVSKIKDSSWNLDMELNEDGSGI
                     ISTFIKVEDIDCYASILFFIGNNAKVIEPKFLNKLLYDKANELRYFYEENMV"
     gene            46903..47625
                     /locus_tag="PC466_001311"
     CDS             46903..47625
                     /locus_tag="PC466_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein"
                     /protein_id="HDF2768703.1"
                     /translation="MENFNKNAKIIGIGVEGINIINEVEEKIKANMDIEKININQEIE
                     KEYVRSLLDGVDILFLIYSSEDKHIRDIIKAVSYMSNERRVLSIGMDCSEKENKEDLE
                     LGREFKINNDSIFKFVDLMNIMVESISDSCMINIDITDLKEAIVGDKGIKYSFEEFED
                     TKSYSEIADILFDRMEYIGEEFISKKGIVFVEGSPEFSIMELNDLISNIQSKVEESYE
                     VIFSLYIKENLNGNIRVGLLYN"
     gene            47654..49588
                     /locus_tag="PC466_001312"
     CDS             47654..49588
                     /locus_tag="PC466_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF2768704.1"
                     /translation="MSENIRGTEYWLMEEFFYQETDTPQIFIEESIIALGFDIKINLK
                     KVFSMGKKSEKYINENCNDKDFIKKFMSIKKGDYFLYKAYQNIEEKVKCNVSIGIVEE
                     DFENGYELSHILGHTLPVKWMHNFDTVSNCKVYTSEFYKLNNNDISSYLEIIKSQDKK
                     LLRKRIEESENNKWYLKNYYYKNVDKCVDDEELFIQPINLEQLESLKNIKTDDYILLY
                     NSEKVICENDHTMKSLFGVCQVMEGFDKEKVSALDGGYFFPVRWIEYGKENIDGNAWV
                     IFENNSIVEKYVKRFTNKMPLNTILYGPPGTGKTYNTKQMVYNLVSETSLRNKYYTGY
                     LDYKNNVEFCTFHQSYGYEEFIEGLKSDGEGNFKPEDGILKDISIEACYNALKFEKKM
                     SFELEKDSLTLETIKDRKKKLVLENIEYSESFNFEESENYVLIIDEINRGNVSKIFGE
                     LITLLEDDKRLTKSNQTIVKLPYSKEKFSLPPNLYIVGTMNTSDKSIALLDIALRRRF
                     NFEEIMPDYDLLSIVDGIDIRKMLYTINKRIEFLYDRDHVIGQAYLLAVENINDIVVV
                     FRSKIIPLLQEYFYYDSEKVGLILGGIGRNEKDKYIVYKEKLIASELFKNNNASIMES
                     KVNYCIKQNISSEELKNIYE"
     gene            49581..>50806
                     /locus_tag="PC466_001313"
     CDS             49581..>50806
                     /locus_tag="PC466_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HDF2768705.1"
                     /translation="MSKNIYVKETYEWIRVGNGENELTEIEYEKLLKYLENNNDVLKS
                     NIIDIKYKKIRFINYVGIICFENVILEILPKLSLSDNLVKDREILLQMLSICNKIPIT
                     MNEKIRLSLKNYNLLNFFVMYFIESMQTQMKKGIYFEYINKIENLNVMRGKILLSTYA
                     KEKGISPMKIRCEYDECSENNFLNQVLKKACISILCRINDNSIQGKIKKILSYFQNVD
                     LIYIDRKKLLGYKFYKNNDRFKDCYLLARLLLLNLSMDNSQNNQEAFSILFEINTLYE
                     EYIGILIKSIWDNSFRETYIQDKSKFLLKNEQTGKKNFNLRPDIVLYDLKNEYEIIID
                     TKWKAIEVDSNVFYRSSDIYQMYAYITAYENAKRCILLYPCIQKDKNYSSWKLSESFK
                     GKFIEAKTVRLDDIKNT"
BASE COUNT        19633 a         5692 c         8164 g        17317 t
ORIGIN      
        1 aaaataatga gataaatata tataaagctt aatttttgaa cttatggttt tgttttattt
       61 taacatattt atatttaata aactataatt gaaatctatt tagataaata attatttatc
      121 taaatagatg aaaattttcc aaaatagata aaatgtgata gaatatattt tgcgaggtga
      181 taacatgatt tcatacgctc cattatggaa attgttaatt gacagaaaaa taaagaaaat
      241 ggaatttgta aatatatcag gtataagtat ttctgtttta ggcagactag gaaatgataa
      301 atctgtttct atggatacaa tggagaagat atgtttagca ctagactgta aaatagaaga
      361 tgttgtggaa ataaaaaagg gcatttaata atactagaat attttataat attccacaag
      421 atacaaaaaa taatagatta attttaatct gtggaataat atatgaaatt tctatgaata
      481 gtaaaaataa ttgttttagt agtgttataa tgttttgaca gggtatattt attattagaa
      541 aggattatta tatgaaaaag atatcaattt taggttctac aggctctata ggtaaacaaa
      601 ctttggatgt ggttagagaa catagagata agtttgagat agttgcaata tcagctaaca
      661 gtaatattga attattgcta gaacaaatag tagagtttaa acctaaatat gtaacagttt
      721 ttgaggaaaa taaggcattg aaattaaaag aaatgttgcc taaaaatata gaaatagaag
      781 ttttagcagg aatggaagga ttaaaaataa tatcatcact tgatgaagtg gatgtccttt
      841 taactgctgt agtaggtatg ataggattag tcccaactct ttgtgctata aagaagggaa
      901 tagacatagc attagcgaat aaagaaacgt tggtaactgc tggtgaactt gtaatgaaag
      961 aagcagaaaa atacaatgta aatattcttc ctgttgatag tgaacatagt gctatatttc
     1021 aatgtctaaa tggagaaaat aaaaaaaata tagaaaagat aatacttaca gcatctggtg
     1081 gtccatttag aggaaagaaa aagggagaac ttgtaaatat aactaaaaat gaagctttga
     1141 agcatccaaa ttggagtatg ggaagaaaaa taagtattga ttcttcaacg cttatgaata
     1201 aaggacttga agtgatagaa gctagatggt tgtttagggt agaacaagaa aatatagatg
     1261 tagtagttca cccacaaagc ataattcatt caatggtgca gtatgcagat agctcaataa
     1321 ttgctcaatt agggtgtcca gatatgagac taccaataca gtatgctctt acatatccag
     1381 atagaatgga aagtagcttt gaaagaatga atttttcaaa atttagtact ttaacttttg
     1441 aagaaccaga tttagaaact tttccatgtt taaaattggc ctatgagtgt ttaaaaatgg
     1501 gaggaactta ttcttctgtt ttaaattcag caaatgaagt tttagtaagt gaatttttag
     1561 aggataaaat tggtttttat gacataccat attacataga gaagacttta gaagttcata
     1621 gtagcataag cgaaccaaca ttagaagaaa tcttagaaac agatagatgg agtagagctt
     1681 atgttgcaaa tctgataaaa aaataggaag gtgaatttat gactataata gccgcattaa
     1741 tactatttag tataattgta ttaatacatg agttaggaca ttttatattt gcaaaaagaa
     1801 gtggtatcaa agtaaatgag ttttctatag gtatggggcc taagatatat agtgtaaaaa
     1861 aagatacaga gtattctata agagcacttc caattggtgg atatgtcagc atggaaggtg
     1921 aagatgaaga acaaataagt ccaaattctt ttggaaacaa gtctatatta caaagattta
     1981 gtactattgt agcaggacca atattcaata taatattagc agcaatactt ttagttccag
     2041 tatttttgta tataggttct ccaacgacta aattaggaaa gataatgcca gatactcctg
     2101 cacaggctgt agggcttcaa gtaggagata agataaataa aattaatggt aattctgtta
     2161 agacttggga tgaagttgca aatataataa acacttcttc tggtggagaa ttaaaactta
     2221 gtataactag agatggaagt aataaagttg taaatgtaac acctaaaaat aacaatggaa
     2281 agtatgaaat agggattcaa ccacaaagag aaaaagactt tttggcgtca atagtaaatg
     2341 catgtaaaac tactgtagat atgacaaaac agatgttaac atttctaggt caaatgatta
     2401 caggacgtgt accaggaggg attggcaatg ctgtagcagg accagtaggt gttattggta
     2461 tggtatcaga tgctgctcgt acaggcatca taaatgtagt gtatttagca gctgtcataa
     2521 gcttaaattt aggtatagta aatctattac caataccagc acttgatgga tggagaatac
     2581 ttatgctatt actagaagct gttagaggtg gtaaaaaact cgacccaaac aaagaaggca
     2641 tgataaatgt tgttggtttt ggagctttaa tgttatttat gctttttatc acatataaag
     2701 atatattaag attatttcaa tgatttagtt ttttagagat tttaagaaaa taggctatgt
     2761 agttttaaat aagaataaat taatttttat gtatgaaatt tattcttatt taactagata
     2821 gctttttaat ttataatata catgtaggtt ataatatttt actatttaaa gagattcaat
     2881 ataaaataat atatagaggt ggaatatgag ttacgagaga agaaagacga gagaagtaag
     2941 tgtaggaact gtaaaaatag gaggagaaaa tcctataagt atacaatcta tgacaaatac
     3001 tgatacaaga gatgcagatg ctacaatagc tcaaataaag agactagagg aagctggttg
     3061 tgatatagtt agagttgctg ttcctgatat taaagctgct aagaatatag caaagataaa
     3121 gtctagtgta aatataccaa ttattgcaga tatacatttc gattataagc tagcccttga
     3181 agctatagaa caaggtgtgg atggaataag aataaatcct ggtaatattg gaagtagaga
     3241 gagagttaag atggtagttg agaaatgtaa ggaaagaaat ttaaaaatta gaattggagt
     3301 caatggaggt tctttagaga aagaactttt aaaaaagcat ggctctgcaa ctgctgaagc
     3361 attagttgaa agtgcaatgg gacatattaa gattcttgaa gacttagatt ttcataatat
     3421 agttatatct ctaaaatcat ccgatattta taaaactgtt gatgcatatg aattaatatc
     3481 aaaaaaagtt gattatcctc ttcatattgg aattacagaa tctggaagtg ttcacaaagg
     3541 aacaataaag tcttctatag gggtaggagc acttcttctt aaaggaattg gagatactgt
     3601 tagaatatct ttaacaggcg accctgttga agaggttatt gttggtaaac agattttaag
     3661 aagtttggga cttttaaatg ataagattaa agttatatca tgccctacat gtggtagatg
     3721 taatatagac ttaattagtg ttgtaaatga ggttgaagaa aagattggta gtatggaaaa
     3781 aaatatcact gttgcaatta tgggctgtgc tgtaaatgga cctggtgaag ccagagaagc
     3841 agatataggt attgctgggg gtaaaggtga aggtctttta tttaaaaagg gtgaaatagt
     3901 tagaatgatt gatggtaaca aattagttga tgagttgcta gaagagattg aaaaattata
     3961 gtatacaatt catatatata ttaattgact agatttttaa atacttttgt aataagtttt
     4021 tatttacagt atttaattat ctagtcattt tttattttat aaacttcatt aaatgtaaga
     4081 aacttatatt ctaatttgac tatatatgta tgagttaaat catattgtaa atttataaaa
     4141 ttaaaaaaag atttaatata gtgaaaattt ccatcaatag tattgaaact tgatagtaac
     4201 tatgatagga tatagttact agaacagttg gtaaattatg ttaacataga ttttaatgtt
     4261 ttggtaaatt gttttattat aagttaatag aaaaagaggt gaagaactgt gagatataaa
     4321 aaaatatcta gcttacctat tttagttgtt gctttgctga ttactggaac gacaacaaca
     4381 ttttctctta gtacgaccaa ttcagaaaaa acaaatgtat acttagcaag tacggtaagt
     4441 actgtcacaa agaaagtatc cgatattcaa agtagtaaag gtcttgttta taatgagaat
     4501 attccattat ttataaataa tagcaaaata cagtatgatg atactccata tcattggcct
     4561 agcaatgtta taagcttaac aaatagcagt gaaaaggcaa ttatggatta tgagattaca
     4621 tgcttagcat atgataaaaa tggaaaacca cttgagctat attgggatgc tcaaaatgtg
     4681 gcagcagatg gcgaagtagg aagtgttgga tttagcccag ctggtgtaga ctatggtatt
     4741 gttacaggca tatctcctgt gtctccaaaa tcatattcac atacttatag aaaaatgcaa
     4801 caatcaccac cacaggatat aataagtatg tttgaaaaac aacaaggcaa ggcatgggta
     4861 gaaaattggt tgaaagaatg gaaacaaatg gagaaagaat atgcaaagca aaatgcaata
     4921 gcaccaggta agaatcaaaa tgatgccttt ctattgtttg ataaatggaa acaatcaact
     4981 ggagagcatg gtgtaaagta cattatatct tgtgtaaaac aagtaacatt taatgatggt
     5041 agtatatgga aaaattcagc atatgagaat tggttgaaaa gttttcaagg gaaggaagtt
     5101 tcaaatagtg tattagaaaa ttactataag taatgtttaa tgatagcaaa atgagtacga
     5161 atttaattaa tgttaattta attaaataag gactattttg tttaaaaata tcagtgttac
     5221 aaggaaattt ttattgtgac aaaatggtat atattcaaaa taaaaaagca tgtgtcaagt
     5281 tttgatacat gcttttttat tttgaatata tgttttctat aaatttatga ttttttagtt
     5341 atgtaatttt atatgtgaat ttttagattt ttatatagat agtgaaataa tgtggaagtt
     5401 ttatgtttta aaaattttag ttaaaacatt tattaaaaaa gataatagaa atgttttaac
     5461 taaaatagtt agaattgaaa tgttatacag atagtataag tactatcaaa ttatataaga
     5521 ttgcttgaag ttaaataatt tatttaaata gaaaacagct gatttaatat cagctgtata
     5581 tgaataaaat tttgaattgt agtgtttagt tatatggata taattcataa taagttagca
     5641 ataaatcaac cattttacca taactctgag taccttcagt aacgccatta gcttttaagt
     5701 aagaattgtt aaactcatta gaaatttcat taattttacc ttcatatttt tgccaaaatt
     5761 cactttcatt ttttaaatct ctacggacag aatctgaaat gccagcagaa atatcaacat
     5821 atgcattata atcaacctta cttaaagcag aagcagtata atttaaagct aaaatatatc
     5881 cagaatagtt aaaatcaata tgggggtgtt ttatagaagt aagatacgct ataaaattag
     5941 cctcatcttc actagcaaat cccctttgat gtgctatttc atgttcaact gtacaaggaa
     6001 tatataagtc aggtattgct atatttacat ttgcctcacc tgtaaaagga aagtatatac
     6061 cagttattcc tgtatagcac attagatttg atgaaataat atacttaggc ttagaataac
     6121 taccactaac actaggtaat atatccaaga tattatcgta tcctagttga gctctattta
     6181 tgacaccatt ataatctgta ttagatttta caataccatt tttatcttgt aatgtgagtt
     6241 ttctagtttc atttgcttta attacaagga atttatataa tttagtaagc tctttaacac
     6301 tatattgttt tgattggata gaggtattgt tttttaaatt atagttattt ataagtgtgg
     6361 tttctagtgg aatcctatta tagtttattc cccaaagcac tacaaaaaga aagtagacta
     6421 ttgatacaat ggataatata tttaaaatgg aattttttaa aaatatgttt aatttttttt
     6481 cttattaaaa attgtagata aagtacaaca taaaaataag aagatagata taactattat
     6541 gtacattgta atctcataga gagaaaatgg gaaaattcca gaaactttac tcaatatttg
     6601 tacaattatt ttatctatga attgggagta atatttttca acaatatttg gaactttgct
     6661 ggctataaaa tttaaaagta aagcaatagg aaagagaatt aaagaaaaat attttgtttt
     6721 tttgctcata tttcacctca catacattag tttatataaa catattatat atcaattgaa
     6781 gaaagattgt aaaataagta taaatatatc tatttataac tttatactaa ataaatgata
     6841 agttataata tattaatatg aataagcagt atatatacaa ctaataataa gaaaaatatc
     6901 aattatataa ggagtagata aaaatatgat aataaaactt actaaagaca attttaattt
     6961 tagatttaaa caatatgaag gtatgttttt tcatgctgaa gtagttgaag gtatggaatc
     7021 cattagatat aaaataacta aggataaaga aggtacagaa ttaaaagaat ttggaagtac
     7081 acatataaaa gataatatga tatatgtacc tcaggtagaa gcatacatag atttgaacag
     7141 tataaaataa agatgtaaaa ttttaattaa aaataaagat tatgtttgag ggggaatcca
     7201 atatgagtaa gcctatagat ataacaataa gacctataag aagagaagat gcacaagctt
     7261 ttaatgaaat tagaagaaca tacagtgtta tgagaaatac tttggcatta atgagtgaca
     7321 gagtcgataa aactgaagct atgttagctt ctttgggaga aaatgattat atgtttgtag
     7381 ctgaaactaa taataatgga gaaaaagatg taataggttt tgctgggtta catgtaaatt
     7441 cttctccacg attgagacat agtgcagaaa taggaataag tgttgcagag aattatcagg
     7501 gaagaggagt aggtaagaag cttatggaac aacttttaga tatagcagat aattggatta
     7561 tgttaactag agtaggatta gaagtaattg tagataatga aaagggatta aatttatata
     7621 aaaaactagg ttttgaaata gagggaacta aaaaatatgc tgtaatcaga gatggaaaat
     7681 ttgaagatgt ttatattatg ggaagatata ataaaaattt aatttaaaga agctaataga
     7741 gaagtaaaat agagtgtctt taataaaaaa tttacattaa aaataatcta ttttacttct
     7801 ctattgtatt aaaaaactta tttttaaatg tttacaaaaa cattctatat acaaataaaa
     7861 ttattagcaa tatcaacgct attttaaaag ctaaactagc aacagtttta atgattttta
     7921 cagaaacacc tatagcaact atagcaaata ctattttaaa gagtaaatcc atatccatat
     7981 ttaagcctcc tattctataa tacatataga tattattgac aaatatctag gaaaaaattc
     8041 catcaatata ctacaataaa atgtttatat ttgtaattta ttgaatatgt tattatataa
     8101 tacataaaaa aataaatcaa gataagagta aaatacttat aaaaggtata gatataactg
     8161 aaaatagtgt tgtaaaaaac acacattgtg aagctagtgt tatattggag tcatattgat
     8221 tagccattat agcagtattt gcagcagcag gcattgaaga aattactact ggtatagcta
     8281 aaatcatctt atcatttatc catcctttta gaataaaata cacaatcaca ggaagtacca
     8341 ataatcttat aaaagtgact atatataatt ttttgttgac aaaacaatcg agagctgaag
     8401 aattagcaag taagcttcca atgataatca tggatattgg tgtagttata cttcccaaca
     8461 tctcaagtgg ctcgtttata aattggggta acctaagtcc tgttacaaat aaaaaaagtc
     8521 caataacaat agctattgta gcagggctta taagtgattt tattgaaaaa cctctacttg
     8581 tactgccttt agataaaaga taaattccta aagtgaaaga aaataagtta aaaggcaaat
     8641 tgaatattgc agtatagaat attgcttcat gacctaaaac tgcttcaatt acaggataac
     8701 ccataaaagc aacatttgaa aaaacaacta tatactgata tattcccaaa tcttttttat
     8761 cattacattt taaaatgtat ttcaataaaa atgcaattat aattgaaact atatacataa
     8821 tcaaagatgt aaataataac aatagtattt tttgtatcat tttactatca aagttaattt
     8881 gcatggagct aattatcatt gatggtaaaa aaactgtcat tgtcaaagtt gaaagcttag
     8941 atgtgcagtg gtcatctaat aagttgaatt ttctgacaaa atatccaact aaaataatta
     9001 taaataaaac tgcaacttgg ataaaaatat tgctgaaatt cataaaatgt ccccccctat
     9061 atatacatta tataccaatt acataataaa atctaatgat tataaaattt aaaatttaat
     9121 gttacaatat agtgacaaaa ggtaaaaatt caatattata gcattaatta tagattataa
     9181 tgtataataa tgtttgagag aatatatttt ataaaatggg taggtagcga ataatgaaaa
     9241 atacaaaatt ttctataaaa aaaataaaaa atatatctaa tgacccgaaa gtcgtacata
     9301 ctaagggtgc cctccttgaa aagatgggta agatggaaag cgcaatagag ttgtataaga
     9361 gtgctgcatt ggataattac gtaaaatctc aatatacttt aggaaatata tatgaaagta
     9421 aaaaacaatt taaagaagca gaaaagtggt attcaatggc atataaaagt ggaagtgaag
     9481 atgctgcttt tgatttaggt aatatgtact ataagttaga tggctatgaa tatgctatat
     9541 attggtatga aaagatagca aatttaggtt atttacaagc acaaaataat ttaggtgtat
     9601 gccattttaa aatgaaagat tttgtaaggt gtgaaaaatg gttaaaaaca gcagcagaca
     9661 agaatttagg taaagcttgt tttaatttag gggtattata tacttttttg gagaaagatg
     9721 atgaagcata tgaatactat aaaaaaggtt ctgtgctttt agatgatgat gcaaaatata
     9781 atttagcaat attaaatgga aaaaagaaag ataataaatc aacagtaagt ttatataaac
     9841 agttgtacaa gtcaggtcat atgaaaggtt gctttaactt gggtatgatt atggaaataa
     9901 atgataattt agaagatgca gagaagtatt ataaaaagag tgctgataga gatgatgtga
     9961 agtctgagta taggcttgca tatgtatatg atagaaaaga agagctggga gatgcaattt
    10021 attattatga gaaagcaata gaaaaaaatc atacactttc taagtataga cttgctaatt
    10081 tatataatag agaaaatgag atagagaagg caaaaactta ttataaaatg gctgctgaag
    10141 atgatataac agaagcaaaa aataatctgg caggtatata ttttgaagaa aaagattatg
    10201 aaaatgctat taaatattat gaggatgcta tagctgttgg atgcaaaagt tcccttgaaa
    10261 atcttgggga tttatattat cagaatcaag atatagaaaa agcgatttcg tattattcga
    10321 ggattccaaa taatgcatct tgtcaaatca aattaggaaa tatctatgaa gatttaaata
    10381 atattgaaga agccataagt tggtataaga aagcatctga aaatggagat acgaggtcta
    10441 gttatagatt ggggtgtata tatgagagct taggaaatac aaaaaatgct agaaagtatt
    10501 ttgaaatggc aagtagcaaa aatcatatga atgctcgtat acatctaggt agaatttatt
    10561 ttagagaagg taaattggaa gagtctaaaa tgatgtttga tacacctgcc aatgaaaata
    10621 atgtgtacgc tcaacatatg gtaggattaa tttatgatat gttctataaa gattatgtaa
    10681 attctaaatt ttggtatgaa aaggctagag cacaaggttg tgttgaatca atatataatt
    10741 taggccaaat ttatttaaaa ttaaatgatg acgcagaagc tgagaaatat tataaagaag
    10801 gtattaaata tggaagtaag aagtgtgagt atatgcttgc aggtctttat tataaaaaga
    10861 gcctagatat gtacatttct ttagcaaatg aagagtacga taattgtgaa gagatagtag
    10921 aaggctttcc caatttaaat atagactttg atgaagtatt aattcctcca tttaagttgc
    10981 aagaagaggt aatagatgaa gaagagtatg taccaattta tatactaaat ataaaagaaa
    11041 gtttagattc aatgctagaa gggcttgaaa ctgaaatgat tatagatgaa gaacatgata
    11101 gttaaaaagt attataagat tatatagatt taaatatata aaagccatta ggataaatgt
    11161 aaatcaatta attctaatgg cttttttatt aatattttat aatagcttat ttcttgacat
    11221 gaaaaatgta atcactatac atattataga ggtaataaga agtattatcc aaaatccgtt
    11281 tgggttatta gaaaatggca tgttgatgac attcatacca aagaatcctg atattattgt
    11341 aggtattgag aaaattagtg taactactgt taaaatttgc ataacattat tctgattatt
    11401 acttataatt gcactgaaag catccataat tctactcaat atatctccat atattttagc
    11461 catatcaaga gcctgtctat tttcaactat aacatcttct aataggtctt catcatctgg
    11521 atacttcttt ataccagcag ttctaaccat tttgtttaaa acaagttcat tagattttag
    11581 tgaggtagag aagtatacca aagatttttc taattccaat aattgaacca attctttgtt
    11641 tttcattgat ttgtaaattt ctcgctctat tatgattgtc attttattta tttttcttaa
    11701 gtaatgcaag taataagctg catttttgtg aagaatttga agcaaaaagc gagtcttttt
    11761 aaacgtaaaa aaatctttaa tatgaccaac tataaagtca tttaaaatct tagtctgtgc
    11821 atcacaaact gttacaatag cttcttcagt tagtataata cctaagggta ttgtagtata
    11881 atgagaagaa ttagagtcac tttcgtctac tggtatatct ataagtataa gagtatgatt
    11941 gtcttcaaca tctattcttg agcgttcttc ttcatctagt gcagattcta tgctttctac
    12001 atctatattt aataaattag aaatttcgtt gatttcacta tgattaggtt caacaagatt
    12061 tatccaacag ccatcttcaa aaaaactaag tttctctaat tttgaatcta tagttttgta
    12121 atatcttatc atggcaacac atcctttatt cagttttata taaatctcat catttaatag
    12181 tatctattaa ttaactaatt tatataactg aatatatgta ttagttttga ttttagatat
    12241 tattaagtga tgaaaatgta aaaaattctc tccgcaacgg actagtatcc attgcccatc
    12301 actctcctta tttattattt tatatatagc tatttatgaa atgcgtattt taagcactct
    12361 ttaatataat accttttcca ggtatataaa tcaagttttg atttgattaa ataatatttt
    12421 taccataatt tacacataaa gtatataagt tatatttaat ttgagtaaag aatatatata
    12481 ttctgagtga aattattaaa tatattaaaa aataagagtg tatatatata tttacttatt
    12541 tgcaataata tatttaaaaa agtattttat tttcaaaact agacttcatt tataatttat
    12601 cacgaaaata aaaggaatat aaatataaga gaatgagagg ttattagaga tatgagtgat
    12661 tttaaagaaa ttttggcaga agagattaaa aataatccat ttggattgat aggtaaagat
    12721 tggacactta taacagcaga aaatgaaggt aaagtgaata caatgactgc tagctgggga
    12781 ggacttggag ttatgtgggg aaaagatgtt gcttttgtag taataagacc acagcgttat
    12841 actaaggaat ttatagataa tacagataaa ttttctctta cattttttga tgaagatttt
    12901 cgtaaagagc tttcatattg tggaaaggta tctggtagag aagaggataa gatatcacag
    12961 attggattta atatagaaca cttaaatgat acaccttatt ttaaggaagc taaaatggct
    13021 attatatgca aaaaaattta tagtcagaaa cttgaacccc aatgttttat tgctgaaggt
    13081 atagatggaa gatggtatcc acaaaaagat tatcatactt tatatatagc tgaaataacc
    13141 aatgtacttg taaaagaaga ttagttataa gggttaatac tatctctaat taaattaaaa
    13201 tttcaataaa aggaaattga cacaaaaaag ctaaggacat aaatatgttt ataaagatta
    13261 ataaataacg tattaaaact ccttagcttg ataaaatttt aatttagttt tctttaaatt
    13321 ataattcaga aatcaattca ttgataacat cttcaacagt acttaattta tcaattttat
    13381 aggcatcatt tccacaaaat aaaagtgaat tttcaacatc tcctttaact gcattgatta
    13441 gagcttgaga aatacagtaa ggagtttctt ttggattaca aggaatcaaa caattatagc
    13501 acttctttat ttctggacga tttattttaa cttcttctat aaatttgttt cttatggcgc
    13561 gtccaggaag acctacagga cttttaacta tatgaacatc ttcttcacta gcatttatgt
    13621 atgccatttt aaagttctca tgggcatcac attcgtaagt agcaacaaat cttgtaccaa
    13681 cttgtacacc acttgcaccc atatctatat attttttaac atcactacta gaagttatac
    13741 caccagcagc aactactggt atgtttctac caaatttttc tccataagta tttgcaacct
    13801 ttaaaatttc aacaaattcc ttatcatagt ctatagaatc tatgttatca agttcctcgt
    13861 tagagtatcc aaggtgacca ccagcttttg gaccttcaac aactattaag tcagcagtag
    13921 ttttctcttt tctatcccac atttttaaaa ttacattagc agcttttgca gttgaaacta
    13981 tgggtgctat ttttacatta cttcccttta ctaatgatgg tagcttatta ggtaatccag
    14041 ctccagatat tataaggtct acaccagctt taacagcttc ctttacgtat gtttcatatt
    14101 ctttcatagc taccataaaa ttaataccaa taataccacc atttgagatt tctttggcct
    14161 tagaaatatg tttttttata gctcttaaat ttgcatttat agtattagtt tcaaaatctt
    14221 cctcatcata tccaatttga actccagaaa ttacaccaac accaccaagc ttagcaactg
    14281 caccagctag tgatgaccta gatataccaa cgcccattcc accttgaatt ataggaactt
    14341 ttgcaactaa atctctaatt attaactctt ttatgataat ccctcctcaa tgtaaacatg
    14401 tttaaagaac tagattataa tacttaatat tattacctag tcctaattat tatactacaa
    14461 attataataa aagagtagtt atattttgta tagaagacga taattatatt atatttaaaa
    14521 cagctccatt agaatcgcaa cataactctt ttatttccca atcagatttt agtttttgta
    14581 ggtaattttt catattatcc acaaaactat catcattttc ttttattaaa gacattatag
    14641 taggtccagc tccacttaaa aatactccaa tactatttaa ttgttcagat ttttcaacaa
    14701 tatcattgta gttctcaatt agagttcctc tataattttg atgcaatttg tcttgacaag
    14761 ctactttaag taggtcaaag tttttgttta gtaaggcaga tattagtaaa gcaactctac
    14821 taacattgaa taccccatca gaatatggta tttcctttgg taaaacacct ctagcttttt
    14881 ctgttgataa cttaaaatta ggtatcattg cacaaaattt aagttcttca ggaattttta
    14941 taatatcata atgtatattc tcattatcag taacagatac gatcatattt cctaaaatag
    15001 caggagcaac attatctggg tgaccttcta tttctgaagc tatatttaat aattgatttt
    15061 tatctaaatt agcacctgat agagcatttg cagctataac tccagctact atacaagagg
    15121 cactactgcc aagacctcta catataggta cttcactgtg gatttttatt ttgataccag
    15181 caggtatttt ttctggttta actctatcaa aaaagtactt catagatgta taaactaagt
    15241 tattttcgtt tttgtaagca tcttcacaac cttctatttc aagaccactt tcaatttctt
    15301 caacataaaa tttattgtat atatttaacg caattccaag acaatcaaat cctggaccta
    15361 tattagcact tgttgcagga actataatct ctaacataat aatcacctat acctttaaga
    15421 atttttttat agctagtttt aattcatctt tttcataaat atctttatgt agtatttctg
    15481 catttttaag atttttaata ggttttggaa tatctatttt agaaatactt gataatctat
    15541 caattatagc aaagtcatca aggtctttaa aatcacaatc tatagacttt agaacatctt
    15601 cagaaaactt gaatggactt gcagtactta caataacagt ttttgtgtta tcagaagttt
    15661 cttttttata tttttcataa caattgtatg caacagcagt atgagtatct atcaaataat
    15721 tataattttt aaacacattg tttatcgtgc ttttaacttc ttcttcattt gaatattctc
    15781 catagaatga ggctaaattt ttttccatat catcacttat tttgtagact cctttatcac
    15841 taaggtctga taacagctta tttacaatat cagtatttct atttgatatt tcaaacagta
    15901 atcgttctaa attacttgaa attaatatat ccatagaagg agaagtagtt aatttcaatg
    15961 ttctattttt atcatataca ccagttttaa agaaatcata aagaacatta ttatcatttg
    16021 atgcacatat caatttgttt attggaagac ccatttgttt ggcataatat ccagctagaa
    16081 tattaccaaa attaccagtt gggacaacaa aatttatttt atcatttaaa tttatctcac
    16141 tattgctaac taatttcata tatgaataaa aatagtatgc aacttgtgga agaagtcttc
    16201 ctatattaat tgaatttgca gaagataata tataattatt atccaatagt ttttgattaa
    16261 attttttatc agaaaaaatc ttctttacac ctgattgtgc atcatcaaaa tttcctttta
    16321 taccaactac atatgtattt tttccagttt gagttttcat ttgaagtttt tgtactgggc
    16381 ttacaccatc ttctgggaag aatacaatta tctttatttt atctatatct ttaaatccct
    16441 caagtgcagc tttgcctgta tctccagatg tagcagtaag aatcacaaca tctttctcta
    16501 aattatcttt ctttatagat gttttaagaa gatgaggcat tatagtaagt gccatatctt
    16561 taaatgctaa agttggaccg tgatatagtt ctaagaaata agtatcattt actttattta
    16621 atggagctat actactacaa tcaaactttt catcatatgc attttctata caatttttaa
    16681 tttcatcttc agtaaaatca cataaaaatt tactaagtac aaaaaatgct atctgagaat
    16741 acgttaaatt tactaaattt ataagttcat tttttacatt gggaaattca cttggaacat
    16801 aaagaccacc atcacttgat attcctttta ttattgcttg tgatgcagtt actttttctt
    16861 cggtgcctct cgtacttgaa taatacattt tttataatcc tccatatatt ttaaattttt
    16921 aattagctaa ttaaattaga tacagaatat tttaaaaacc gaatttaggt aataaaaaaa
    16981 gaccctcatc cctaaaaaag ggacgagaat ctgtttcccg cggttccacc caaattgatt
    17041 ttaaaaaatc cacttgatac tttaacgcaa gtaataaaaa cgtctattcc tactaaaatc
    17101 attaagataa cttcggatag aagctcctag gtagttttca atccttctaa ttagggaaac
    17161 atttcagcta gtagtttcct tctctggtaa tcgattcaga tttactcttc ctaatcaatg
    17221 cctttcaata ttcttaatat tattaattat tctagtttat aaaacagaca aagtcaagta
    17281 ttaatataaa aatttggaaa aaatattttt taaattgtaa aaaaattgta atcaaattga
    17341 gtattagaaa aatatttttt taactttttt aaaagtttaa aaacctagat tttcatagtg
    17401 atgaagctgt ttttaatgaa agtaatcaaa agataactat taaatatctg taatattaca
    17461 attttatact acactatatt acaaaaaaag tttacaaaac tttaatttga aaaatgtaat
    17521 tatatggtat atcatataaa tataagtaaa tagtgctaat atttaaacta ttaatcataa
    17581 ttggttcaac aaaagtatat agttaataat gtttaatttg aagaaattgt tagtgtgaaa
    17641 ttacatatat attcaaatta aattcataaa tatttcacat aataatagta tactgtaaac
    17701 aaaaggaggt attaaatatg ggaatagtac ttataacagc agcattagtt ttggttatgt
    17761 atggactttc aattctatca tatatatcag aaagcaatat attagaagac actgtaaatg
    17821 ataaccaata aggttttgaa ttatataaat aagtgagaac tgtaaataaa agttaatttt
    17881 tatttgcagt ttttttatat atatgtaaaa taaagttaat taataaaaaa taatgttttg
    17941 tttgtagtat atatggataa taatagtaaa gtataagaat gatgagaata atatataaga
    18001 aataataata taaagagagg taaacattat ggtagatatc attgtaattg gtgctggacc
    18061 agcaggttta acttcagcaa tttatgctat gagagcaggg ttaagcgtta cagtatttga
    18121 aaaaaatatt tatggaggtc aagttgcaag tacctctgag gtagaaaatt atccagcagt
    18181 tcaaaagatt tctggggtag aattttctaa taatatatac aatcaagcag ttgctcaagg
    18241 tgttgatatt cagtttgatg aggttgaaga gataaattta gagggaaaag taaaggttgt
    18301 aaaaacttct tcaggtgaac ataaagcaaa ggctgttatt cttgcaaatg gagttgaaag
    18361 acgtaaatta ggttgtgcag gggaacaaga atttacaggt agaggagtat cttactgtgc
    18421 aacatgtgat ggagcctttt ttaaagataa agaagttgct atagtaggtg gaggaaatac
    18481 tgcactagaa gatgctttat ttttagctaa taattgtaca aaagtgtatt taattcacag
    18541 aagagatagt tttagaggtg aagaagtgtt ggagaaatct gtgaaagcaa gagagaatat
    18601 tgagatactt tacagtcatg gtgtagaaaa aatagaagga gaaaagactg tatcgaaaat
    18661 agaagtaaaa aacttaaaga ctgaagaaaa aagaactata gatgttagtg gtatttttat
    18721 tgctataggt cttaaaccta ataataaaat gtttgaaaat gttcttgatt tggatgaagg
    18781 tggatatata atttcagatg agtcttgtac aacatcagta gaaggtgtat atgtagcagg
    18841 agatagtaga actaagtttt tacgtcaaat aataacagca gcatcagatg gagctattgc
    18901 agccgttcaa gcagctaatt atataaatgt tgaataatat aaatttcaaa taaaaatagc
    18961 catataaact gaaataattt ttcagtacta tatggctatt ttgttaatta gaggtaaatg
    19021 tacgttttat ttaccttgtc tagatttgtt atatcttaat ctatcatgtt catttaagaa
    19081 tctttttcta agtcttatag aatcaggtgt aatttcaact aattcatcat cttctataaa
    19141 ctctagtgct tcttcaagag taaatattct aggaggagat aattttatag catcatctga
    19201 accagaagca cgtacgttac tcattttctt gtttttacaa gggttgacta ccatatcatc
    19261 ttttctggaa ttcataccaa ttatcatacc ttcgtaaact tctacaccag ggtctacaaa
    19321 cattacagct ctatcactta aggcattaag agaatacccc atagtaacac caggtccttg
    19381 tgctattaaa acaccatttc ctcttgaagg tatttctcct ttaaattctt caaatttttc
    19441 aaatgaacga actaaagtac cttctccacg agtagcgttt ataaattcac ttcgatatcc
    19501 taaaagacca cgagtaggtg ctaagaactc tatttttaca tagtctcctt ctattgacat
    19561 agactccatc ataccttttc tcatgtttaa ttcatttata atagtaccag agtaaacttc
    19621 aggacagttt acaacaactc tttctattgg ttccattagt tttccatctt ctttatgcat
    19681 taaaacttca ggtttagaaa caccaacttc ataaccttca cgtctcatat tttcaagtag
    19741 tatagataag tgaagctctc cacgtccaga aactttgtat ccatcagtag tatcaagagg
    19801 ttcaacttta agaccaacat ttacttcaag ttccttttca agtctatctt tcaaatgtct
    19861 agttgtaacg aattttccac tttttccaac gaatggagag tcgtttacta agaagttcat
    19921 agaaagagta ggctcttcta tttttatcat ttccataggt agtggactat ctaaatcgca
    19981 tatagtttca cctatagata tatcaggaat accagctata acaactattt ctccactagt
    20041 agcttcatca acttcaactt gttttaaacc ttcatacaca gaaagttttg atacttttcc
    20101 tttagataca acagaatctt ctctacatat agcaacttgt gtattgtttt taagagtacc
    20161 tttgtaaatt ctacctatac caagtctacc tacataatca tcatatgcaa gagctgatat
    20221 ttggaattgt agaggttcat tatcgtaatt aggataagct tcaacgtgat ttacaatagt
    20281 tttaaataga ggagaaaggt cttcactatc atcatccatt tcaagtttag caataccttg
    20341 tttagcaata ccatatatta taggaaattc gcattgctca tctgttgcat ttaagtctac
    20401 aaataaatcg aaaacttcat taactacttc ttccgctctc tggtcttttt tatcaatctt
    20461 gtttataaat aatattggtt ttaaaccgaa ctctaaagat ttttgtaaaa cgaatctagt
    20521 ttgaggcatt gggccttcac tagcatcaac taatagaata actgtgtcaa cagttttcat
    20581 aacacgttca acttcagaag aaaagtcact gtgtcctgga gtatcaacta tgtttatttt
    20641 gtaatcttca tagtttattg cacagttttt tgaatatata gttatgcctc tttctttttc
    20701 aaggtcgtta ctgtccataa cgcagtcttt aactacttcg ttctttctaa aaacaccgct
    20761 ttgagaaagg aaagcatcaa ccaatgttga ttttccagcg tcaacgtggg ctataactgc
    20821 gatatttata attttatgtt tttgtgacat ttttgttgct cccttcgatt aaaataactt
    20881 attaattata gcacaatata ttattaggta caaggaggaa tatattaaat tgtattaata
    20941 tagtttaaat tggataaaac tgttagtttt gcatctgaaa attattctgt ttaaaaaaat
    21001 tttttagaca aataataatc ttaatagata aaaagattaa taaaagagta aaggatgata
    21061 tatgttggaa gtaaccaaaa taataattaa atattttgca agtgaaagtg atacttttat
    21121 aaaagaagaa gtttgtaatt ttgaagaact tcttaagtgg tctcataaat ttattgaagg
    21181 taaaaagata gaagatgttt tgtatataaa gtctaaagaa aactataaag taaatgtgat
    21241 taagtcttta gaaattaagg aattggaaat agtgagaaaa caacagatac caccgtacat
    21301 gtagtattaa taatatataa aattaatatg taatactcac aataggatat aaatggtata
    21361 tatggtaata atttatatta aaaaaacttt tataaagttt atatttgggt ataaaagtat
    21421 taattagaca ttaattagga ggaacttaaa tatgataaga gtatgtccaa actgttcaaa
    21481 tgtggatgta aataagctaa aaactttggt tggagaagaa aatgtaaaga ctggttgtat
    21541 aggtcagtgt agagcattta aaaaagaagc tgttggaata atagacaatg agcttgaaat
    21601 aaaggaaaca gaagcagagt tttttgaagc atgtaaagaa taaattttaa ataaaatata
    21661 aattataata aatagagcat ctaaattgta taagcattaa acaatttaga tgctctattt
    21721 ttatatatac atttaattat gagtatactt ttctattaaa tacaaataaa tataactaat
    21781 acatttattt attaaaaaaa tattgattta atatacctat agggggtata ataaaaatat
    21841 agatttctaa ataagtaatt tatcaatatt acatatcaaa ataaaacgtt acaaattagc
    21901 tgaaaatata ttgaaagaaa ggaagatttt attatgagtt caaataaagt ggtagaaagt
    21961 tataaaatta caggtatgac atgtgcagct tgtgcaaagg cagtagaaag agtaactaag
    22021 aagatggatg gagtatatga ccaaagtgta aatatagcta ctgaaaaact taaaatagaa
    22081 tatgataatt ctaaggttaa ttttgatgat ataaagcagg ttgtagaaaa agcaggatat
    22141 ggaattataa aggaagaaag taataaaaaa attgatatga aaattgatgg aatgacatgt
    22201 gcagcttgtg caaaagctgt agagagagtg gtaaaaaaat tggatggagt agaaagtatt
    22261 agtgtgaata ttgcaacaga taaagctaat atagactatg acccatcaaa agtaaaatta
    22321 tctcaaataa aagcagctat tgaaaaagct ggatataaac caatagaaga ggtaagaaat
    22381 aaggttgatg tggatgaaga taaattgaga aaagaaagag aaatgaagtc tttatttgtt
    22441 aaatttatag ttgcaatagt atttgcagta cctctgtttt atatagcaat gggacctatg
    22501 ataataaagc ctatagggcc atggcctttg ccagaaatta taaatcctat gacaaatact
    22561 tttaattatg cattaattca gttaatttta gtaataccag taatgatagc tggttataaa
    22621 ttttatataa atgggtttaa atcacttttt tctttaagcc ctaatatgga ttctttagtt
    22681 gcaataggaa cattagccgc atttttatat agtctatata cgacactaca aatagccaat
    22741 ggacaaattc aaggtatgca ccatcatcag ttgtattatg aaagtgcagg aataataata
    22801 gcacttatct tacttggtaa atatttagaa tcaaaatcaa aaggaaaaac atcagaagca
    22861 attaaaaagc ttatggggct acaacctaaa actgcaatag tgttagttga tggtaaagaa
    22921 gttgaaactc ctatagaaga agtagagata ggagatatac tattagtaaa accaggaact
    22981 aaaatacccg tggatggagt tgtaatagaa ggatatacat cagttgatga atcaatgctt
    23041 acaggtgaaa gtataccagt agaaaaaaat gttggaagta aggtgacagg agctagtatt
    23101 aataaaaatg gtgttattaa gtttaaggct gaaaaaattg gtggagatac tgctcttgcc
    23161 caaataataa agttagttga agatgcacaa ggtacaaaag cacctattgc taaacttgcc
    23221 gatactgtat ctggatattt tgtaccaata gtaattgcaa tagctgtagt tgcatcatta
    23281 ttgtggtttt taataggagg aaaagatata gtatttgtac ttactatatt tatatcagta
    23341 cttgtaattg cttgtccttg tgcattagga ttagcaacac caactgctat aatggttggg
    23401 actggaaagg gcgcagaaaa tggaatcttg ataaaaggtg gagaggcact agaatctgca
    23461 cataaagtaa atacagtgat atttgataag acaggtacta taacagaagg aaagccaaaa
    23521 gtaacagata tagtattaaa taataatgta aaagaagaat atcttatcaa gattgcttca
    23581 agtgcagaaa aaggttcaga gcatcctctt ggagaagcaa tagttaagta tggagaagag
    23641 aagaatataa aatttgaaaa agttgataat tttaaagcca taccaggtgc tggtatacaa
    23701 gttactatta atgatgaaag tatattactt ggaaatagaa agcttatgaa tgacaataat
    23761 ataaagcttg gggatttaga agaaaaatca aatgtattgg caagccaagg taaaacacct
    23821 atgtatatag ctgtagatgg aaatttatca ggtataatag cagttgcaga tgtagtcaaa
    23881 gaaagtagta aaaaagcaat agaaatactt catgatatgg gaataaaagt tgcaatggta
    23941 actggagata atgcgaaaac tgcaaatgct atagcaaatc aagtaggtat agatatggtt
    24001 ttggcagagg ttttaccaga agataagtca aaagaagttg aaaaactaca aaatcaagga
    24061 aagtttgttg caatggtagg ggatggaata aatgatgccc cagctcttgc aaaagcagat
    24121 atagggatag caataggaag tggaacggat gtagccattg aatctgcgga tatagtactt
    24181 atgaagagtg atttaattga tgttccaaca gcaattaaac ttagtcatga aactataaaa
    24241 aatataaaac aaaacctatt ttgggcattt ggatataata cgattggtat acctgtagca
    24301 gcaggaatat tatatgtatt tggaggacct ttattaaacc caatgattgc agcagcagca
    24361 atgagcttaa gttcagtttc agtcgtatca aatgcactta gacttaaaaa cttcaaggca
    24421 tataagagag attagattaa taaattaaat aaaatgtatc caaaagagct atctttaaat
    24481 taaaaggatt aatttacaaa ttaagatagc tcttttttca tgtaaaattc acaacaataa
    24541 gataaaatat aagtaatata cgaaatttta aataaaatag aaaggattga tagaatgaat
    24601 tcgtcaatac ttgtaattga agatgattca aatatacaag agttaatatc agaattttta
    24661 agtgcagaag gttatcaagt tgatacagca aatgatgggt tggaaggtat acaaaagttt
    24721 aagcaaggaa gttatgattt agtaatatta gatataatga tgccaaactt agatggttat
    24781 ggagtttgta aaatgataag aaagtcatca agcgttccaa ttatattttt aactgcttta
    24841 aatgatgaag gagaccaact taaagggttt gacttagaat gtgatgatta tataacaaaa
    24901 ccattttcat ttaatcttct tataaaaaga gtagaagcaa ttttaaggcg aagtaacaag
    24961 actataaatg acaaatttat agtttttgaa aaattaaaat tagatttaaa cacatatatt
    25021 gcagagatag atggagaacc tatagaactt acactaaaag agtttaatat attaaaagct
    25081 ttgatagaaa agtatccaca agttataact agggaaggtc ttttggatag tatatggggt
    25141 tatgactatt atggagatac taggattgtt gatgcacata taaaaaatat aagaaaaaaa
    25201 atatcgttac catatattaa aactgtaaaa ggaataggat atacacttga gaaggatatt
    25261 tgataagtgg gaaaagttaa gtataaagta taagttattt tcaataacga catcattatt
    25321 aatagcgtta gctttaataa tatatctaat tttatatttt ttattgccat catattatca
    25381 tgagtataaa attgagtctc ttcaagaaag tttaaaatct ttagtagata gttcaattca
    25441 tttcgataca tatactttag aagaaagact ttattatatg gctaaagacc aaaatttggc
    25501 tattttatta aaagataacc aagggaaaat tgtatatggt aagaatgaag tagttatttt
    25561 aagatatagt aagtacatga ttaatagtct tgaggatgag tatagaactt ctatacctat
    25621 atatactaaa gatgcaaaag atggtccata tactttagaa ctcgttatgc cattacaacc
    25681 aattgacgaa gcaaacgaag ttataagaaa actaatgcca tacatcatat caatagcaat
    25741 attgatagcg attattggag catatatata ttcaattgta ataacaaagc ctcttataaa
    25801 tataatagag agtgagagag aacaggaata tagaaggaag gattttgttg ctacaatatc
    25861 acatgaacta aaaactccaa taaccataat aagtggtcaa attgaaggta tgatttatag
    25921 tgtaggtaag tataaggata gggatactta tctgaaaaaa tcatatgaat gtacacaaga
    25981 attaaaagat ttagtaaatg aaatgataga ggtttcaaaa tcagaaatac ttgaaaaaga
    26041 tttgaaattg gtatcaataa atataagtga attattaaat agacttgtaa agagacaagt
    26101 atttttaata gaagaaaaac atatgaaaac tattttaaaa atagaagaaa atttggaaat
    26161 taaagcagac caagagagaa taactaaggc aatcaataat ataataaata atgccataaa
    26221 atattctcct gaaaaatcag agcttataat tagactctat gataaaaata aacgaataag
    26281 taaaaagact tctaatcaaa gagtggtttt agaaattgaa aatactggtg taactatcga
    26341 gaaacgttat ttagaagaga tatttaatcc attttataga atagaaaaat cccgttcaag
    26401 aaaaactgga ggaagtggac ttggacttta tatagtcagt caaattttta aaagtcatgg
    26461 gtttgattat agcataaaaa acaaagaaaa ctctgtagta ttcacagtag aatttaaaaa
    26521 ttaattactt attataaaga atatataact ttcaataata gttcatttta aaatcacaaa
    26581 aaattcataa tgaaactgta ttatataaat ataaagaagc ttaaaaccat aaaatacacc
    26641 aactataatg atgagatttc cttacatcct ccatataagt catcattata gtaacccaac
    26701 aattaagtta ctatgaattt aaaaaataac accgagcata taatctatgc ttagtgttat
    26761 ttttattttg aaataaaaaa tatttaattt attgaaatgt atagatttag acagtttaaa
    26821 ctatatttaa gacttaaaaa ttataattga tattacaaat aaatatatgt actttgggaa
    26881 aaataaatat aggaagtatt atatttacag aggaggtagt tttgatggat agattaaaaa
    26941 gagatatgaa aaatatgaaa gaagatttaa aagaaggtgt taaaaagaca gcttatgtta
    27001 tgaaaaatac agctgaagat ttgaaagatg atgcacaagg tgctatggta aacttagaaa
    27061 tgaaaaaaga tgagatgatg gaaagatatg aacaaaagaa attttctaaa gaattagaga
    27121 agcaaatgaa gaatgaaatg aaataagctt ttatttatga ataacaaatt attgtattca
    27181 tataaaaagt agccagtaat attaaatagt ttatttaagg aaatagactt tctaaaaata
    27241 actgtattag atttagaaag tctatttcaa attagtttta taaatagaca taaggataaa
    27301 gtagatgtta tagaactaga ttttaaaaaa tagatactaa ggataaaata aatattatag
    27361 aaatatgttt ttaagaatag ttatcaaata aaaatttata tttataagaa atcctataaa
    27421 atatataatt aaacttataa aacatttaca ttaaattctg ataaaatatc tactatatca
    27481 ggagtaggcg ctttttctgt aattatagaa ctaatatctt ctaaatgagc aaacttgaaa
    27541 tttccatcaa atttaaactt tttatcttcc ataactataa atactttttt acttgaattt
    27601 attatagcct tcttcgtgag accatcttca atttcaaaag ttgtaagtga agagttgaat
    27661 acatctactc cacaacttcc cataaaagtc ttatcaaact tatatttcga tataaactct
    27721 atagttggag taccgacaaa accgtctaaa ctgagattta ataaacctcc agtggaaatt
    27781 atatttaaat tatttggttt tgaagtaact acatttagta tatccaacat atttgtaaca
    27841 agtgttactt ttttattact ttcagctaac aactttgcaa gcaagatgtt aattgtagag
    27901 atatctaaaa atatagtttc tctatcttca attaaattaa atgctttttc tgctattatt
    27961 ttctttgttg gaatattaat ttcttttctg tcttttgtat cctgattctc tagtgtttct
    28021 ctagctagta cagctccccc ataaattctt cttattgaag aaatcttttc tatatttttt
    28081 aaatcttttc ttatacaatc ttctgtaaca ttaaatttag aactgagctc tttgacagta
    28141 actctacctt ctttttttag gatatttaat atagcttgga ttctttcttc tgcaaacatt
    28201 ttctacctct tttcgcaata tagtattata gtaaatatta taagataaaa tacaatatat
    28261 caactatttt aacatgaaat acaaaattaa tttaatataa aaagtatgtt ttttctaact
    28321 atatatttag aatttagtaa ataaaaaaat tataaaacta agaaggaaaa gcaaaacaat
    28381 aataaaaaat aaaaaacaat aagcaaaatg ttgaaaataa taccaaatca atatataata
    28441 agaataaaga aagattaaag ggggatattt taatgcaact aatcttagat acaggtaatg
    28501 tggaggagat taaggagtta tgtacttgtt taccaataga tggtgtaact acaaatccaa
    28561 gtattgtttc aaaagaaaaa aagaatttta agcaacttat aaatgaaatt ggtgagatta
    28621 taggtgagga tatgcctata catgctcaag tgttaagtac aaagtatgaa gaaatattag
    28681 acgaagcatt atatataagt agtttgagaa aaaatatata tgtaaaaata cctgtaacac
    28741 aagatggttt aagagctata aaagaccttc acagaaaagg tgtaaaaata actgctactg
    28801 caatattcac tgctcatcaa ggttttttag ctgcaaaggc tggagcaaat tatattgcac
    28861 cttatgtaaa taggcttgat aatatatctg gtgatggagt agctatggtt tcagaactta
    28921 taaaaataat agatacttat aaaatggata caaaagtact tgcagccagt tttaaaaatg
    28981 cacaacaagt tatagaatta atgcaacatg gggtgcatag tgttacagta ccatatgata
    29041 tttgtaaatc tatgatgaat catccattaa ctgattggag tgtagataag tttatagagg
    29101 attgggagaa tacttttgga aaaggaagta aaacaaataa tatttagtat tatggtaaaa
    29161 gagtagtttt gtccaatttc acaagaactt atataaaaag atgaaaatat gaattttctt
    29221 tttaataatt tcgttattat cttaagttaa ttcatatttt catctttttt agatttctag
    29281 tcctataaat ttccaccaag ggaatgttat acatattatt ataaagtagg ttaaaggaat
    29341 caaagttaaa ccgtatttga aaataacctt gctattatac agattttcac catgaccaac
    29401 cattattgta gcatgatgaa atggtaatat gtactgtatg cttactataa tgtagacaaa
    29461 tagacataaa gtaacactat tttcctttag tatatgtaaa cttccaagta atggtattac
    29521 tacagatgat gtagtgacag cacttccaag acatatattc aagattattg tgagagttat
    29581 caaaaacaat attgaaataa tttctgaaga gtttggtata aactttatca aataatttcc
    29641 cattatatct acaactccag agtactttaa cactcctcca attgaaaatg ctgctataaa
    29701 aaaaataagg accttccaat ttatttcttt taaagtacta aatccaacta tttttcttag
    29761 taataaaaga agtacacaaa ttgacattat aattaatgtg tttatgttat gtatgaactg
    29821 agttaaaaac ataaaaaaca ttattcctag gcataaaaat acgtgttttt gctctttgtt
    29881 tagcaaatta aattcttttt ttaaattaga atatgaaaaa tgaagtttat taccctcaag
    29941 attttcatta gaaataaatt ttattgaatg caattctttt ttaaagacaa agataaataa
    30001 aaaataagtt ataaaacaag taattatagt tggaacagac atataaaaag cccattgacc
    30061 ccaatttata ttacaatttc caagttctag tacaacataa tttagaaggg tgtctccatt
    30121 tacaaaaaac attgatgtaa aggtagatgc tgtaaatata ctaaataaaa gtatagattt
    30181 tgaatcttca gttatctgtt gttcttttaa aaactccttg taaaaagcag atacaagaat
    30241 aacccttgga aatggttgtg ggataaaaaa tattaaaaga atacctaaaa tatacgataa
    30301 aagaatcatc tttttagggg tatttacagt atttaaaatt aacttctcag aaataatttt
    30361 tgcgacacct gtttttgtaa ctgcattagt aattatgtat gcaagaatta ttatgtaaaa
    30421 attttctgta aataaaaact gtaaaataac ctttattggt gcaatgttaa atataaacgc
    30481 tagaattaca aaaaacaatg caacaaaagt tttttcaact gagtctacag cccatatcaa
    30541 gatagttaaa aaagataagc atatagaaaa ttttatgttg aaactgtaat taagagagaa
    30601 gtagagaatt atggtaacta taacagtcat ataaaattgt tttggcttaa gaataatacc
    30661 catttttata ttcacctcca taatttatta tatcataatg gaggtgaata caatgaatgt
    30721 gaatacattt tataaaaaga ttattcattg attctatgat ttacaatagc tttagttttc
    30781 caataccctt tcttatagta gataactgta acaataagac ctaaagtcca accaaaagga
    30841 atacccatcc aaattccgtc tgttccaaaa aatttagaaa gcatataaga agctggaagt
    30901 cttccaagcc ataaagatac tattgagctt ataagtgcaa acatggaatc accagcacct
    30961 ttcattgcac ttgaaagtac aaaagaagtt ccaataaata aaaagaatgg tcctattata
    31021 aataagtaag aagagccaat tttaatgaca tctttatcag tattgaatag agcaattaga
    31081 ttttccctaa atagcaaaat taaagcaata actgtaactg ctaaaactaa ggtcattttt
    31141 atagattctc gaatgccttt tttaaccctt tcattttctc cagcacctat gttttgagca
    31201 acaaaagtag aaacagcaga accaagattc ataataggta agcttataaa attttctatc
    31261 ctaagaccag caccaaaagc tgccatagca gatgtaccat aactattaac taaaaattga
    31321 agagtcatat ttccaattga aaacaacatt tgttgaattc cacttggaag tcctaatcta
    31381 agtccatctt taaatatttt gttatcgtat acaattcctt tgattttaaa tttaagcact
    31441 tcatgttttt tatttaaata aattatactt attataaatg atactgcctg agccattata
    31501 gtggcaagtg caacgccctc aacacccatt cttagcacta caataaaagt taagtctaaa
    31561 actatattta gaattgtggc tattatcaga aaataaagtg gagttactga atctccaagt
    31621 cctctaagta ttgcacttac tgaattatat ccagcagaaa ataatattcc actaaatatt
    31681 atagtaagat acaattttga ttgagcaaaa acggattctg gtgtattcat aagcttaagc
    31741 attgggccac caaatactat tccaagaata cttattaata tagaaccaat aaataaaagt
    31801 atatatgtag tatcaatagt agcttttacc ttttttaaat ctcctgagcc ataaaattgt
    31861 gacactaaaa tagaaaatcc aaggctaaca cccataagcg ctgccaccaa taaaaacatt
    31921 atagggttag ctccagagac tgccgccatt gcttcttttc cgataaatct accaactatt
    31981 atactgtcag ctgtattgta tagttgttga aataaactac caataagcat aggcatggca
    32041 aaaaagaata tggattttcc ctcatgacct gtagttaaat ctttcacctt attcctccaa
    32101 ataaaaaaat tattaattta ttatagtata atcttaacat aaactttata tccaaactat
    32161 aaataaattg tatcaaaata tcatatattt ttttaaaatg taaagaatat aattataatt
    32221 tgaatttaat aaatcaatat ttaatataat cgaatattaa tacaaaatca atacaatata
    32281 tacgtatata ttgacaaaat taattatata aattaaaata atattcgtaa agaaaaattc
    32341 atgttttgta ctgtataaca tataattttg acaatatggg tcataagttt ctaccggaat
    32401 accgtaaata ttctgactat gtatactatt atttagttaa ttaaatattt aattaactga
    32461 attatgaagg atacggctca gcttatcaac tactgtgtcg tttttttgta aaatttaata
    32521 ggaggtgttg ttatgcaaac aacaaacagt agtactatgc agaaactttt tccaattttg
    32581 actaataaaa atgtcgacat gaagaaggaa ataattgcag gagtaactac ttttttaact
    32641 atggcttata taatagctgt aaatccaaat attttatctg agacaggcat gcctgcaggt
    32701 gcacttgtta caggtacttg tttagcagca gcatttggat gtattttaat gggtgtagtt
    32761 gctaaccttc cttttgcttt agcatcaggt atgggtctta atgcattttt tgcatataca
    32821 gtagttttac aaatgggtgt tccttgggaa gtagctctta cagcagtatt tgtagaaggt
    32881 attattttta tagtattatc agtaagtgga gttcgtgagg ctgttgtaaa tgcgatacca
    32941 aaaaatatga aattagctgt tacaggtggt ataggaatat ttattgcact tataggtcta
    33001 gttaacagtg gaattgttat tggagaccaa gccactctta tcaaaatggg tagatttaca
    33061 ccagcagtaa taataacttg tttaggatta ataattattg ctgtattaga taaaaaaaga
    33121 gttaaaggtt ctatactttt tggaatagta gtgagttcat tacttgcttg ggcatttgct
    33181 tttatgaatc cagagtatgc acaaaaatta ggtatatatt tacctggtgg attatttaaa
    33241 ttcgaaagtt tagcaccaat agcaggtaaa atagatttag gatatgtact acatccaaca
    33301 aatataggtg gttttttagt agtagtttgt acatttttat ttgttgattt ttttgataca
    33361 gtaggtacat tagttggtgt ttgttctaaa gcaaacatgt tagatgaaaa agggaatgtt
    33421 cctaatgtag gtagagcctt acttacagat gcggttgcaa ctacagttgg tgcaggactt
    33481 ggagtatcta cagttacaac ttatgttgag agttcaacag gagttatcgc aggtggaaga
    33541 actggatgga cagcaataac agttggaatt ttattcttag ctgcaatgtt tttctctcct
    33601 gtatttatag caattccatc atgtgctaca gcaccagctt taatatatgt tggatattta
    33661 atgcttggta cagttaagga tatagagttt gataatataa ctgaaggtgt tccagctttt
    33721 gttactattg cttgtatggc attaacatat agtataggtg atggtttaac tttaggtata
    33781 ttaacttatg ttttcgtaaa tatattttat aatatatttg gagctaaaaa ggcagaagac
    33841 aaaaaacatg tttctgtagt aatgattgtt ctggcaatat tatttataat aaaactttgg
    33901 ctattataat aggtattatt taaaatttta atttaatata aaataaaggg ctataattta
    33961 ttatcaattg tgatgataaa ctacagctct tttgtatttg ttgtattttc gtatttattg
    34021 tattatttaa taatgtctat tagttctcca ttttgtaaag ttttaggtgt aattactata
    34081 ctgaactctt tttgcaaatc ttttataata tctaattctt tttttgttat tattgagatt
    34141 gtgttaccac ttcgatttcc tctagaagtt cgaccacatc tatgcaggta ttcattttta
    34201 ctttttggaa aatccaagtt aaaaacatga cttacatcca caatatctag tccacgagca
    34261 gataaatcag ttgtaattaa aatctttgct ttaccaagtt taaatttatt tattgcattc
    34321 tttctatctt ctttttccat atttccaaaa attcctattg ctttgtaatt atgataattt
    34381 agttttgata ctaggacttc tatatttttt tcattattta caaatacaat agcttttttt
    34441 ggatttgtag ctgctaatgc ctttctaaga aaagtaaatt tatcccttat ctcacctaat
    34501 aaatatgagt gattgatgtt aggatttatt tgtgattttt cctttgtttt tattatttca
    34561 aactccttca taagtttatc acaaattttt atagtgctat cagtaagact tgcagagcat
    34621 cctataattt gtctatctct taacgttgtt cttattatgt cttctataca agttatattt
    34681 tttccattca atagattgtc cacttcatct aagactatag tttttatatt atgtgatttt
    34741 agcttctttt gttttatcaa gtctaaaact cttccacaag agccaattac tatgtgtggt
    34801 tttactgctt ttatattttt tatttgtttt tgtatattga cctccccaat taaagctaaa
    34861 gaagtaacgg agagttctgc atttttagcc aataattcaa cctggtttgt aatctgcatt
    34921 actaattcat gcgtaggtgc aagtataaga gcttgtgttt ctctttttga tgtatcaatt
    34981 ttttcaaata taggtaaaag gtacgctagt gtttttcctg ttccagtctg tgaattaatc
    35041 aataaatcct tattttgaat tatattccct ataacaagtg actgaacttc tgttggagaa
    35101 gttatgtctt gttttttaag tccatctatt agagtggaac ttatttttaa ttgttcaaat
    35161 gtattcatat tttgctcctt atatttaata attatagtca actatttttt attatacatt
    35221 gtttattcaa atcgaactat atattctttt ataattatgt gtaatttgaa agtaaatatc
    35281 aattatattt atacctttat atttctgata cctttgcatt ttatagattt ctaaaataaa
    35341 caaataaaag ttgtaattgt ttgatatttg ttatatatta tatataacaa atatcaaaac
    35401 tataatatgg agggaaatta tgttaaaagt aatcaatgta tctaaatcat ataaaaataa
    35461 aaaagtagta agtagtgtct catttgatgt aaatgatgga gagctttttg ggtttatagg
    35521 acataatgga gcaggtaaaa ctactactat taaagcaatt gttggaatac acgattttga
    35581 agagggagaa gtactaataa attctaaatc tataaaaaaa cagcctgttg aatgtaaaaa
    35641 ggaaatggca tatatacctg ataatccaga tttatacgag tcattaacgg gtatacaata
    35701 ccttaatttt atagctgaca tatttgaagt tgccaaagac aaaagagaag agttaataaa
    35761 atattattca aataagtttg aactcaataa agcattagga gatttaatat cttcatattc
    35821 gcatggtatg aaacaaaaat tagctataat ttcggctttg atacacagcc caaaaatctt
    35881 aattcttgat gaaccttttg taggtcttga cccaaaagct tcctttatat tgaaggaaat
    35941 tatgagggag ttttgtgaca aaggtggttg tatatttttc tcaacacacg ttttagaagt
    36001 tgctgaaaaa atttgtgata agattgccat aataaaagat ggaaatataa ttgcttatgg
    36061 aactacagaa gaagttaagg gaagtaattc acttgaaagt atctttatgg aattaataga
    36121 gaaataaaat gttttttata caatatagtg tctaaagtga ggaatgataa aatatgagca
    36181 atctaagtat attaataaaa actaatataa taaatgaatt taaattaaat gcgttaaaaa
    36241 aagctgatag tagagaaaaa caaaaaataa tggggatgat actttcagtt gttattataa
    36301 cagggttatt gattttttat gtaactagta taagtctttc tttagttgat attttaaagc
    36361 aaataaatca gatggaaatg ctacttatat ttggatttgg attatcaaca ttaacaacta
    36421 ttgttacatc attatataaa acgtcatcat atctgtttca agcaaaagat ttagaccttt
    36481 tgactagttt acctataaaa gaatctactg tactagcaag taagatatta atgttggttg
    36541 gagcaaacta tttattttct tcaatatgta tgattatacc agcagtggtt tattttttta
    36601 attctgatgt aagtataacg tatttccctt atttgatact gctattttta gctttaccat
    36661 tattaccaat agttgcttca tcaataattt ttatgtttat aggacagata tcatcaagaa
    36721 taaaatacaa aaatttaata ttaattatag gtagtattat attgatgttg ctttatactc
    36781 tacttatgac aagacttaac tctatgtcgg ttgagatgtt aaagaatagt gtatctattt
    36841 cagagacgat tagaaaaata tatccaccta tatattattt tgttgacgct cttaaaacag
    36901 gaagtgtagt ttccttttta gcatttatag caatttcaat aataccattt tttatgtttg
    36961 taacattatt tgcaaaaaaa tttaaagata taaatgctaa gatgagtgaa ggatataagt
    37021 caaaaactta taaatttaag agccaaaaaa cttcaagacc ttcaaaagct ctattaaaaa
    37081 aagaatttaa gagatatact tcttcattta tatacttttt aaattcatct gcaggtttgt
    37141 tattcctaat aataggtaca attttaatat tattatttgg agcagataaa gtgggtgagt
    37201 tactgaaatt gaatatagat tttaatttta taaaaataca attattggga gtattcttct
    37261 ttataatagt aatgaattgt acaacatact gttcaatttc tcttgaagga aaaaatttat
    37321 ggatactgaa atcttctcca atagatgaaa gagaaatatt ctggtcaaaa atattgatga
    37381 attttttatt gaatgcacca ttatctattt tatgtttaat attagtatct ataagattag
    37441 gttttgaaat tcagtttatt attgtatcaa tctgtttgat tgcaagtttt tcaatgtttg
    37501 tggcattgat gggattatta tcaaatttat tatatccaaa ccttgattgg aaaaatgaga
    37561 tggctgtagt aaaaagaagt gcaagtatga taattacaat gttagtatca ttagcttacg
    37621 taattatact tggaggtata tatgtattac ttggaatttc gtttttaaat atatatatta
    37681 ttttggcaag tatacttact tttatattag attttatgat atggagaatt atttctacta
    37741 aaggagtaag aatatttaaa aatttatagg tgtatttatg tcaaataaag acttatcttt
    37801 tttagtcttg caaataatag gttaagtagt atactatgta tagtgatatg aaaaaattta
    37861 ggagaaaata aatgagaaaa ttatccaaaa gagaaaaaga ttttattcaa tatggatttt
    37921 tattattttt gatatgtatt actacttatt tagtattaac tactttagat ataaaactaa
    37981 tacctaaaat tataaggcta gtaaataaga cttatatatt tcttggcata ttgacaatta
    38041 tagtatatat gataattgaa tctattgtaa ctcatttgat aataaatgca gttcaaaaaa
    38101 caaaagtaaa atttattggt attaaaatgg ctacaatggg attttactat aacttagtta
    38161 ctccatttgc atctgggagt caaccaatgc aaatatatgc acttacaaaa tatgatgtaa
    38221 gccttagtaa atcagtggct atagttacta ataaaactgt agtatttcaa agtacagtta
    38281 ctgtattttg tggaatttta attttgctaa ataagtcatt actgatggag caagtacatt
    38341 ctgtgaaagt cttgataact tttggaatga ttatgaatgt aagtatgttg ttaggtggac
    38401 tattaatagt atttagtcca aaacaagtaa aaatgatagc agaagttttg attaattttt
    38461 tatctaaatt taaaacattt aaatttttag attcaaaacg tgatagaata aatcattata
    38521 ttgatgatta taattattct ataaaaatat ttattaaaaa tgtaagaatc ttagttttaa
    38581 gtatattact tactgtgtta caattaatcg catatttcag tatagtttat tgtgtgtata
    38641 aagcctcaaa tttaagagga gtttcatatg tacatataat gacattacag gtctttttat
    38701 atatggctat atcaccaatt ccaacaccag gaaatgttgg agctaatgag gttacatttt
    38761 ttactatgtt ctccaatata attccaaaag aattattggg gtactctgta ctcttatata
    38821 gtgggtttgt atactatttt atattaatag tttcaggttt atttacattt ggaacgcatt
    38881 atacattaaa ttcttggaaa aaggaagata aagtaaattc taatttagat aaggttattg
    38941 aaaaattaaa ttaataaaat aattagggaa attctatata taaatatggt gttgagtaag
    39001 ctatattata ttgagatatt tccctttttt gattaaaatt atagaaattt gaaataataa
    39061 gtaataaaca gaaaaagtga tattgttttg aaaggagaaa ctatgaaaca agataaacaa
    39121 aatgaaaaac aaagtgagat ttctaagata aaacaaagca atgataataa acttgaaata
    39181 gctcaagaat tacatgtaag taaaaatata gggaatatgc ttggatatag aatagataag
    39241 aaaaaaatga atagaccaag ttaatgaaaa tgttgaaaat ggtacatttt aaaaaatata
    39301 tataatgaaa tgttttattg ttaaatttaa acttatttta atggaggaaa aagtcgaaaa
    39361 atatctaaaa agatatggat ataaaaaata ttaatatata tatactataa acttgacaaa
    39421 atcaaccttt taataactag caaaaaatag caaaattata taagcgttat ttaattatca
    39481 aaaatgaaag ctaaattgca tgtcctaaaa aaaatgattg ataacattta tttgtgtgct
    39541 ataattatat agtaaaacaa taagtatatt gcataatgta tgcaaatcgg gaggagagac
    39601 ggacatggaa gcatctatac acacaattgc cagcaataat ttattgataa tttttgctat
    39661 tgtaagtata actggaataa tttgtagtaa gcttagtgaa ataataaagg ttccagatgt
    39721 agtgttatat ttacttgtag gtattttaat aggaccatca tttttaaaat ttatagatat
    39781 tcgtggattt caaatagaaa atcaactaat acttacattt ggttctgcat ttattttata
    39841 tttaggtgga aaagaaataa gtttaaaagt attgagaaat gtgaagatat ctgtattctt
    39901 attagctact ttaggagttg tgatatctgc ttttataatg caacaagtaa taggatttac
    39961 ttttgggata agtgcaatga ctgctttact agcaggaact ataatagcat caacagaccc
    40021 agccactctt gtacctatat ttaatcaggt aaagataaag gatagggtaa aacaaactgt
    40081 aataagtgaa tcagctttta atgatgcaac aggagctata ctaacatcag cagtgttggc
    40141 tgtaattttg tcaaataaat tttcattagg tgaaaatatt tatgaactgg ggacaatggt
    40201 tattgtcgga gttttagttg gtttaattac aggaatactg cttttgaaat tagttaatga
    40261 taaaccttat ggaatattta aagattttgc accaataata tctgttattt cagttgtagt
    40321 tgcatatgaa ttatctacaa aattaggtgg aagtggatat atgtcttgct ttattgtagg
    40381 tataataact ggtaacaaga aaaactttaa aatttggtta agtcaaaaat cttatgatgc
    40441 agatttttat gttgctgaaa ctttaggtac tatttgtcgt atggcaatat ttataatatt
    40501 gggtagccaa gttaatttgg ctcagttaag taaatatttt atgccatctg taattacagt
    40561 attagtatta atgtttatag caagaccact ttgcgtttta gtttgtacac ttgtagacag
    40621 ggaagcaaaa tggagtaaaa gtgaaatatt atttatgatg tgggtaaggg aaacaggcgt
    40681 aataccagca gcactttgtg gtattatttc agcaatgaaa gttcctggat acgaagtgat
    40741 ttcatctgta gtatttatga ctatattaat tacattagta atacaaggaa gtactacaaa
    40801 attagtagct aaaaaacttg gattattaga agaagaagtg ataaatataa gtgaaaaagt
    40861 atcaactttt taaagttttg ctttaaaata gtacctgtta atggctattt taatattgtc
    40921 taatgatgat tattgaaata gtcatttttt tatgtataag taatttacag aatttacata
    40981 ttagacatat ttattatcaa aatttgttga agctatgata taattagttg tatttaaaat
    41041 aagaatagca aataagggag gaaatttatg tttacggtta tggatattgt acagccagat
    41101 acagtagaag aagcgtactc aattttaaat aaaagaaaaa ctaaccaagt aattggtgga
    41161 agtgcttttt taagaatggg gaaaaaaaga ataggaacag gaatagaatt atctaaatta
    41221 aatttagatt atataaaaga gtatgaagat tacgttgaga ttggttctat gactactttt
    41281 agaacattag aaacaagttc cataataaaa aataattttg gaagaataat agaagattca
    41341 gttaaaaata taataggagt tcagtttaga aatgtagtaa cagttggtgc aacagtattt
    41401 tctaaatatg gtttttctga cttgatagta gcattacttt cattagatac ggaagtagaa
    41461 ttatataata ttgggagaat tagtcttgaa gagtttctaa atagagatta tgagaaagat
    41521 ttacttatta agatatacat aaagaagaca aataagaatg cttcttataa atcacttaga
    41581 aatgcaaaga gtgattatcc aattctaaat gtatctgtat caaaacatat ggaacaattt
    41641 aagttatgtg taggagcaag accgcagaaa gctacgattg caaaacaagc tagtgaattt
    41701 ctatctaaca atgaaatcaa tgaaattaat atagataaag cagtagaaat agcatcagaa
    41761 gaactaactt ttggttctaa catgagagca tctagggagt atagaaaagc tatgagtaaa
    41821 gtacttttaa aaagagctat aatggaggtt atttaatgtt agtaaagatt aatataaatg
    41881 ggaagaaaaa aagtgttgat atagaaccag aagaatatct ggttgatact ttaagaaaag
    41941 ttggtaattt aagtgtgaaa agaggttgtg acacaggctg ttgtggttta tgtacagttt
    42001 taattgacaa gaaacctaca ttatcctgtg caacactgac attgagagct ttagataaag
    42061 aaataactac aattgaaggt ttagaaaatg aagttaaaga atttagtgaa gttttggtaa
    42121 aagaaggagc tgagcaatgt ggtttctgtt ctcctggctt tatacttact gtacttgcaa
    42181 tgaaggatga gcttgaaaat cctacagatg atgaaataaa gcattatctt acaggaaatc
    42241 tatgtagatg tacagggtat atgggacagt taagagctat caaaacttat ctggaggtaa
    42301 aatagaacat gaatatagtt ggaaaaggaa tcaagaaaat agatggaatg agtatcacaa
    42361 caggaaagcc tgtatataca gatgatttat cagcaaaaaa tgctttggtg gtaaagatac
    42421 ttagaagtcc tcacgcttat gcaaaaataa aagatataga tacatcaaag gcagaaatgg
    42481 ttgatggtgt tgaatgtgtt ttaacatata aagatgtacc aaaatctcga tttacacttg
    42541 ctggtcaaac atatccagag ccatctccat atgatagatt aattcttgaa gatgttgtaa
    42601 gatatgtagg tgacgaagta gctatagtgg cagctataga tgaaaaaact gcaattaaag
    42661 caatgaatct tatcaaagta aagtatgaag tacttacacc tgttttggat tttgaagagg
    42721 caataggaaa taaaactatg gtacatgatg aagatagaca ttgtaacttt gatataggta
    42781 tgcaaagaga aaaaaatata gtatcccatc atgattatac aaaaggtgat gtagaaaaag
    42841 tattaagtaa ttgtgatgta gtgattgaag aaacttatta tactcaagct caagcacatg
    42901 caatgatgga gacgtatagg gcatacaatt atttagacca tatgggaaga ttggttgtag
    42961 taagttcaac tcaaatacca tttcatgtaa aaagacattt atctcgtgca ctagaaatac
    43021 cagctagcaa aattagggtt ataaaaccta gaattggtgg cggatttggt ggtaaacaaa
    43081 ctgcgtgtgt tgagattttt tctgcaattg ttactttaaa aacagggaaa ccagctaaaa
    43141 taatttatga tagaaaagaa acttttaatt gttcaacaag tagacatgca atgagattaa
    43201 aagttagact aggtgctaca aatgatggca taataaaggc aatagatata aaagcacttt
    43261 ctgatacagg agcatatgga gagcatgctt ctacaactat tggtttggtt ggagaaaaaa
    43321 ctttaccaat gtataataaa gttgaagcaa caagatttat tgcagatgtg gtatatacta
    43381 ataagatgcc agcaggagca cttagagggt atggagcatc acaaggatgt tttgctgttg
    43441 aatcaactat aaatatgctt gctaataaat taaaaatgga cccaacagat ttaaggttaa
    43501 aaaatgtggt aacagaaggt gaaactacat ttgcatatgg taaaacttta aatagtgtcg
    43561 atttaataaa atgtataaat aaaggcaaag aacttattgg atggaatgaa aaatatcctt
    43621 gtaaacatct tgataatgga aaaattagaa gtgtgggtat ggcaattact atgcaaggtt
    43681 ctggtataca aggtcttgat aagtcttcag ctgaaataaa attgaatgac tgtggagatt
    43741 atactcttat gataggttct actgatatgg gtacaggaag tgatacgatt ttagctcaaa
    43801 tggctgctga ggttcttgat acaagcattg aaaatataac agttatatca gctgatactg
    43861 acttagttcc atatgaccca ggttcatatg cttcaagtac tacttatgta acaggtatgg
    43921 cagtagttaa ggcagctcaa gacttaagag aaaaaataat ttctgctgga gcaactaaac
    43981 taggtgttga gaaggatgaa gtagaatttg atggtataaa attaactagt aaaaaaggta
    44041 gcactttatt attcgatata gcagttgatt ctacaattgg tccagatact aatcaattaa
    44101 taggtcttgc ttctcatggt agcccagtat ctcctccacc ttttatagca ggttttgcag
    44161 aaactgaaat tgacacagaa actggaaaag ttgatttagt aaattatgta gctgtagtag
    44221 attgtggaac ggttataaat aaaaatctag ctaagataca agttgaaggt ggaattgttc
    44281 aagggattgg aatggcatta tttgaagaag ttagatacac agaaaaagga agcatggaca
    44341 caaatacatt tatgcaatac aagattccag ctagatgtga tattggaaat gttaaagtag
    44401 attttgttga aacttatgaa ccaactggac catttggtgc taaatctgtt ggagaagttg
    44461 ttataaatac acctttacca gcaatacaag aagctgtgtt taatggaatt ggtgtaagaa
    44521 taaatacact ccctattaca cctgaaaaag tttttatgga aatgaataaa taattattta
    44581 tgaaaattta gactagtttt acatgttaaa caaccagtta tgtcatacct gttgaaagat
    44641 atttaataag tagttattat aatattatga attttactta taaaatacaa aattaaataa
    44701 ggggatgatg ttttggctgg taatctaaat aatatgagag cagtaaataa ttttagagga
    44761 gataagaaca ttttagaatg tttagtcagc tttgagggtc gttcaataag tcagagaaaa
    44821 gtaagggtat tttttaaaga aaaacaaaat caaatagaaa ttgattttgc agaagaggaa
    44881 atttctaaat tggttgaaaa tgttgtttta aatacatcat atcaagaaat gttatatgat
    44941 gaaatagaga aacaactgga aattgattgt ataggtactt ggatgatatt atctaaatta
    45001 aaagatggta gtagagttca ctgattttaa aataaattat tagagcctaa ttttaaggct
    45061 cttttttgct gtttttaatt aacaatagaa aatttatctt tagtttgtat ataattttaa
    45121 tatcatatat tctatatata taaaattgaa tttgtatgta ttatattgta taatataaaa
    45181 tgaatttgga aaatagttcg ctaaaataat ttgtttttat aaaattactg tttaagttta
    45241 tagattttgt ataaaataaa gttatgttat taattttttt agaaataaaa cttttactag
    45301 gagacagata tgagaaaaaa tagtattaat atagcactaa ctgcagcaat tacagcaatc
    45361 tatgcagttt taacattatc attgggattt ataagttatg gaccaataca atttagggta
    45421 gcagagatta tgatgctttt ggcattttta gataaaggat atatagtagg tcttacatta
    45481 ggttgttttt tagcaaatgt aataggacca tatggtgtac ctgatataat ttctggaaca
    45541 ttagccacat ttataagtgc aagtatgatt tatattacta gaaagttagg taaacaaaat
    45601 aaaagtactt tagttatagc ttctttatgg ccaactgtta taaattcgat tgtggttggt
    45661 ctaatgttaa atgtattctt tgggcttcca ttaattctat ctatgataca ggtaggtttt
    45721 ggagaatttg tagtagtaac aattgtagga gtaccatttt tctgcttttt aatgaaaaaa
    45781 tataaaaatg tcattaatat taaattttaa atagtgtata gtaatttaat taattgagag
    45841 tattattagt gaaaagaggt gtttatttgt cgaaggtaaa aagattgact gatgtttgga
    45901 tatatattaa tgataagcaa aagtttacaa taaaagagtt gtcagaggaa tttaatcttt
    45961 cagctaaaac aatacaacga tatttaaaag aattaaataa aatgggactt ccaattcaag
    46021 cagaacaagg tagaaatgga ggttataggg tgctaaataa tagctatata cctcctgtta
    46081 tatttacaga aaaagaagtt atgattatac tatttgcact taagtcactt cagatttata
    46141 attataagtt aatggaaata gaaattaatt ctataatgag aaaagtaagt tatgaacgta
    46201 aaagcagtat aaaagtaggt atagaaaata ttaaaagata cattggcttt gtagctaatg
    46261 atactaatga tggagatttt aagagtagta atgtaactga gttttttaga gcttcttcag
    46321 aatctctaat tttaaatatt aagtataagt gtggtaatca gattttggaa aaaaacgtat
    46381 gccctatagg tatatattta aataagggag catggttttc accagcatat gattgtaaaa
    46441 gtgataaaat aatattagtt catatagata atataattga tataaaaaga acaggagaaa
    46501 gtaaaaaaat acatataaac ttggaagaat ggttacatga agtatataac aatttatatg
    46561 gaaatagttc aactactaaa aaatttggtg aaattattta tctaaatgta ttattaacta
    46621 aagaaggtgt ttctaaaata aaggacagtt cttggaattt agatatggag ctaaatgaag
    46681 atggtagtgg aataattagt acattcataa aggttgaaga tatagattgt tatgcttcga
    46741 ttttattttt tattggaaat aatgctaagg ttatagagcc aaaatttttg aataagctac
    46801 tttatgataa ggccaatgag ttaagatatt tttatgaaga aaatatggta taatatttag
    46861 aaatgttgaa attaaataat tattaaggag atatacgtta taatggaaaa ttttaataag
    46921 aatgctaaaa taattggtat tggagttgaa ggtattaata taataaatga agtagaagaa
    46981 aaaataaaag caaatatgga tatagaaaaa ataaacataa atcaagagat tgaaaaagaa
    47041 tatgttagaa gtcttttaga tggtgtagat atattatttt tgatatattc atctgaagat
    47101 aaacatatta gagatattat aaaagctgtt tcatatatgt caaacgaaag aagagttcta
    47161 tctataggaa tggattgttc agagaaagaa aataaagaag atttagagct tgggagagag
    47221 tttaaaatca ataatgatag tatatttaaa tttgttgatt taatgaatat catggtagag
    47281 tctatttctg attcttgcat gataaatata gatattactg atttaaaaga agctattgta
    47341 ggagataaag gaattaagta ttcttttgaa gagtttgaag atacaaagtc atatagcgag
    47401 atagctgaca ttttatttga caggatggaa tatattggtg aggaatttat aagtaagaaa
    47461 ggaattgtat ttgttgaagg aagtccagaa ttttctataa tggaattgaa tgatttaata
    47521 agtaatattc agagcaaggt agaagaaagc tatgaagtaa tattttcttt atatataaag
    47581 gaaaatttaa atggaaatat tagagtaggc ttattgtata attagtatat tttagatatt
    47641 aaggagagtg tatatgtctg aaaatataag aggtacagag tattggttaa tggaagaatt
    47701 tttttatcag gaaacagaca caccacagat ttttatagaa gaaagcataa ttgcacttgg
    47761 atttgatata aaaataaatt taaaaaaagt attcagtatg gggaaaaaat cagaaaagta
    47821 tattaatgag aattgtaatg ataaagattt tataaaaaag tttatgtcga ttaaaaaagg
    47881 agattatttt ttatataaag catatcaaaa tatagaagaa aaagttaaat gtaatgtgtc
    47941 tattggcata gttgaagaag attttgaaaa tggatatgaa ttaagtcata ttttagggca
    48001 tacactacca gtaaaatgga tgcataattt tgatacagtt tcaaattgta aagtatatac
    48061 aagtgaattt tataaattaa ataataatga tattagttca tatttagaaa ttattaagtc
    48121 acaagataag aaattattga gaaaaagaat agaagaaagt gaaaataata aatggtattt
    48181 aaaaaactat tattataaaa atgtagataa gtgtgtagat gatgaagaat tatttattca
    48241 gcccattaat ctagaacaat tagaaagcct aaaaaatata aagacagatg attatatttt
    48301 attgtataat agcgagaaag taatttgtga aaatgaccat acaatgaaga gtctatttgg
    48361 cgtatgtcaa gttatggaag ggttcgataa agagaaagta agtgctttgg atggtggata
    48421 tttttttcct gttagatgga tagagtatgg aaaggagaat atagacggaa atgcatgggt
    48481 tatatttgaa aataatagta tagttgaaaa gtatgtaaaa agatttacta ataaaatgcc
    48541 attaaatact atactttatg gaccaccagg aactggtaaa acatacaata caaaacagat
    48601 ggtttacaat ctagtaagtg aaaccagtct aagaaacaaa tactatacag gttacttaga
    48661 ttataaaaac aatgtagaat tttgtacatt tcatcaatca tatggatatg aggaatttat
    48721 agagggtctt aagtctgatg gtgaaggcaa ttttaagcca gaagatggga tattaaagga
    48781 tatatctata gaagcatgtt ataatgcatt gaaatttgaa aaaaagatga gctttgagtt
    48841 ggaaaaagat agcttgactt tagaaactat aaaagacagg aaaaagaaat tagtattaga
    48901 aaatatagaa tatagtgaga gttttaattt tgaagaatca gaaaactatg ttttaataat
    48961 agatgaaatt aatagaggga atgtatctaa aatatttggt gagctaataa cattattgga
    49021 agatgataaa agacttacta aatcaaatca aactattgtc aaactaccat attcaaagga
    49081 aaaattttct ctacctccaa atttgtatat agttggaact atgaacacat cagataaatc
    49141 aatagcactt ttagatatag ctttaagaag aaggtttaat tttgaagaaa ttatgccaga
    49201 ttatgattta ttgtctattg tagatggtat agatattaga aaaatgctat atacaatcaa
    49261 taaaaggata gagtttttat atgatagaga ccatgttatt ggacaagctt atctacttgc
    49321 tgtagaaaat attaatgata tagtagtagt atttagaagt aaaataatac cacttcttca
    49381 agagtatttt tattatgatt cagaaaaagt aggtttgatt ttaggaggaa ttggaagaaa
    49441 tgaaaaagat aaatacattg tttataaaga aaaacttata gcttctgagt tatttaaaaa
    49501 taataatgcc tcaataatgg agagtaaagt taactattgt ataaaacaaa acatatctag
    49561 tgaggagcta aaaaatatat atgagtaaaa atatatatgt taaggaaacc tatgaatgga
    49621 taagggtagg taatggtgaa aatgagctta cagaaattga atatgaaaaa ttgcttaaat
    49681 atctagagaa caataatgat gtattaaaaa gtaatataat agatattaaa tacaaaaaaa
    49741 ttagatttat aaactatgta ggcatcatat gttttgaaaa tgtaatactt gaaatacttc
    49801 ctaaattgtc attaagtgat aatcttgtaa aagatagaga gatactatta cagatgcttt
    49861 ctatatgtaa taaaattcca attacaatga atgaaaaaat aagattgagt ttgaaaaatt
    49921 ataatctctt aaattttttt gttatgtatt tcattgagag tatgcaaaca cagatgaaaa
    49981 aaggtattta ttttgaatat ataaataaaa tagagaactt aaatgttatg aggggtaaaa
    50041 tattattaag tacatatgca aaagaaaaag gcatttctcc aatgaaaata agatgtgaat
    50101 atgatgagtg tagtgaaaat aatttcttga atcaagttct taaaaaagca tgtatatcta
    50161 ttttatgtag aataaatgac aattcaattc aaggcaagat taaaaaaatt ttaagctatt
    50221 ttcaaaatgt agatttaatt tatatagata gaaaaaaact gttgggttat aaattttata
    50281 aaaacaatga tagatttaaa gattgttatt tactagctag acttctactt ttaaatctat
    50341 ctatggataa tagtcaaaat aatcaagagg cattttctat attatttgaa ataaatactt
    50401 tgtatgaaga atatatagga attttaatca aaagtatatg ggacaattca tttagagaaa
    50461 catatataca agataagagt aaatttcttt tgaaaaatga acaaacaggt aagaaaaact
    50521 ttaatttaag accggatata gttttatatg acttaaaaaa tgaatatgaa attataattg
    50581 acactaaatg gaaagctatt gaagtagatt caaatgtttt ttataggtca agtgatatat
    50641 accagatgta tgcatatata acagcatatg aaaatgcaaa aagatgtata ttattatatc
    50701 cttgtattca aaaagataag aattatagtt cctggaaatt atcagaatca tttaagggta
    50761 agtttataga agcaaaaact gtgaggttag atgatataaa aaacac
//
LOCUS       DAMJYN010000021        49429 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.021, whole genome shotgun sequence.
ACCESSION   DAMJYN010000021 DAMJYN010000000
VERSION     DAMJYN010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 49429)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49429)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49429
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.021"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            30..1310
                     /locus_tag="PC466_001314"
     CDS             30..1310
                     /locus_tag="PC466_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HDF2768706.1"
                     /translation="MNILGLIVEYNPFHNGHIYHLSKSIEKTNATHTVAIMSGNFLQR
                     GEPALFDKYTRAKIAVENGVDLVIELPTLFACQSAEIFSHGAITILNSLNCINSICFG
                     SEEGNTEILYNIAEILANEPNEFKLLLKKYLDDGLLFPTARANALFDYIHQDKKNNFI
                     QNYSKEQLSKTLNSSNNILGIEYIKNLIHLNSSIKPFTISRVQSEYNSEEIESDICSA
                     TAIRTSLKENTDLFHLKNVIPEKTYNILNEKVDNGFLPMFDDFFFDILKTIILRDMDT
                     LKEYFEVNEGIENRIYKDIFTSEFLHELQLAIKSKRYTLTKIKRTLNNILLGIKKSDM
                     QLIKNIDTIPYIRILAFNDKGREILKEIKNKSEIKIINKFSNISFSLDDTIFKTLISY
                     DIKATNIYNSIYYKNNKDLVKGPMDFYTHPIYVK"
     gene            complement(1573..2964)
                     /locus_tag="PC466_001315"
     CDS             complement(1573..2964)
                     /locus_tag="PC466_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HDF2768707.1"
                     /translation="MYKLIDKKDIDFLIDTCGEENVLVGSDINEDFSHDELGGIEKYP
                     EVLVNVLETEQVSKIMKYAYKNNIPVTPRGQGTGLVGAAVAINGGIMINLCKMNKILE
                     VDYENLTLTVEPGVLLMTIGQYVQDRDLFYPPDPGEKSATIAGNINTNAGGMRAVKYG
                     VTRDYVRGLEVVLPNGEIINVGGKVVKNSSGYSIKDLLVGSEGTLGIVTKAILKLLPL
                     PKKSISLLIPFPDLSMAIETVPKIIKSKSIPTAIEFMERDVILAAEEFLGKKFPDNTS
                     DAYLLLTFDGNSTEDIEKEYEKVANLCLENGALDVFISDTQERNDSIWSARGAFLEAI
                     KASTTQMDECDVVVPRDKIAEFIRYTHELQDKLKIRIKSFGHAGDGNLHIYILKDGMD
                     DNTWKIRLKETFDYMYKKSRELSGQVSGEHGIGYAKKEYLHESNSDAYMMLIKNIKLA
                     FDPKNILNPGKIY"
     gene            complement(2975..4195)
                     /locus_tag="PC466_001316"
     CDS             complement(2975..4195)
                     /locus_tag="PC466_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding protein"
                     /protein_id="HDF2768708.1"
                     /translation="MSKIVVNQDKITDLKRILEICPFGAIEEKSGIVEISAGCKMCKL
                     CVKSGPKGAFEFIESSKVQINKDEWRGIAVYVEHHNGNIHPVTYELIGKAREMASKIK
                     QPVYCVFVGKDIKDKCSNLISYGVDEVFVYDEDEFKDFRIEPYSKAIENFIDKIKPTI
                     VLVGGTTLGRSLAPRLAARFRTGLTADCTILDIQSNTDLDQIRPAFGGNIMAHINTPN
                     NRPQFATVRYKIFSAPEKIENTTGKITLCKVEKKELKSKIKVLSVKEKNKEVGLEEAE
                     VIVVASRAIKKQEDMEMIYKLADKLNAQVAGTRPVIEAGWIDAKKQIGLSGRTVKPKL
                     IITCGVSGAVQFVAGMQGADYIVAINKDDKAPILDVAHLALIGDIYDIIPKLIEKIEN
                     NKDNNQKYMASAAK"
     gene            complement(4209..4997)
                     /locus_tag="PC466_001317"
     CDS             complement(4209..4997)
                     /locus_tag="PC466_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003457975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HDF2768709.1"
                     /translation="MEILTCIKQVPGTTSVEVDETTGVLKRDGVDSKMNPYDLYALET
                     ALRIKEDKKANLKVLSMGPPQAKKVIEESFMMGADEGALISDRRFGGADVLATSYTIS
                     QGIKKMGKVDLIICGKQTTDGDTAQVGPEVAEFLDIPHVTNVTKLIEVKDESIVVEID
                     MPNDLQVCEIEYPCLITVEKDIFQPRLPSFKLKLNTKDREIPVYSLDDFEDKDENNYG
                     LNGSPTQVVRIFPPKPNTDKNIVRGNADELSFALVNKLEELKLV"
     gene            complement(5014..6288)
                     /gene="larA"
                     /locus_tag="PC466_001318"
     CDS             complement(5014..6288)
                     /gene="larA"
                     /locus_tag="PC466_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel-dependent lactate racemase"
                     /protein_id="HDF2768710.1"
                     /translation="MVKLKVPYSKQGMILEIPDERFLGVLESKSDNYIEHKTQEEIVE
                     ESMNNPIGSNSLEELVKGKKNVVIITSDHTRPVPSRITMPIILRRIRNVNPEIDVKII
                     VATGFHRPSTREELIYKMGEEIVDNEDIVMHISTDDKSMCKVGILPSGGDLYINKLAY
                     EAELLIAEGFIEPHFFAGFSGGRKSVLPGIASAKTIMYNHCSDFIDSDNSRTGKLNNN
                     PIHEDMVYAAKVAKLAFILNVVIDKDKKIIASFAGDVEKAHTKGCRFVTELSKVNSIK
                     SDIVVTTNGGYPLDQNIYQSVKGMTAAEATCKDGGVIIMISACNDGHGGQSFYENVAN
                     ADSPKQLLDKIRSVDRVDTIPDQWEFQILARILSKYTVIMVTDKCNPEMIKKMHMKHA
                     FNFKEALEMANSIVGKESKVVVIPDGVSVIVK"
     gene            complement(6406..7119)
                     /locus_tag="PC466_001319"
     CDS             complement(6406..7119)
                     /locus_tag="PC466_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HDF2768711.1"
                     /translation="MFNSIASKKVYEQVIEQIQYKILNGELKKGDKLLSERELSEQMN
                     VSRTSIREAIRVLETMGVIESRQGEGNFICTNIEKTLIEPLSMIFKLNNGTLEDILEL
                     RIILEIEIAKLASKRITSSEVIELKHIIDEMRVETNKKDNNRVLVLLDQKFHSKLATL
                     SKNYLIQSLFMTASKLFDGFIEDAREKIIAEPFNENILLKQHEAIYNAVVENDVELAC
                     EKAKEHMDFISKNYRKNEN"
     gene            7244..8503
                     /locus_tag="PC466_001320"
     CDS             7244..8503
                     /locus_tag="PC466_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation integral membrane protein YlbJ"
                     /protein_id="HDF2768712.1"
                     /translation="MKKNKIIAFFAPAIIVGVLVLGIILYPNEAIKSAREGFSIWSNV
                     LVPSLLPFIIGANLIVDLKIVDIIGFIINPITRFVFNVSGKSALAFAISTVSGYPVGV
                     SLASEFRSNGQISKHEAQRLVSFCSTSGPLFIIGSVGTGMFQNSNLGYLMILCHYLGT
                     ILVGLFFRNYGNENLPKTKLDLKTNIKNVINIRNSSGNGFFVLFGNAVFNGVNTLLTV
                     GGFVIVFSVVFKILSLFNVISLIASVIYLPLSFLGVSKELCQAFVSGLFEITIGCNKV
                     SSITSSPEILRASLASFLIGFSGLSILAQCCTFLSKTDIDLKLYILSKFAHGVLAAIF
                     IFILYPIANSAVLVSSFADTYNVIYNNLIWFYYLSYYDTILQIVVIIYLISAVFIAKK
                     HMKTLSTNGKLMRYKNTFFIKKFSRKK"
     gene            8771..9337
                     /locus_tag="PC466_001321"
     CDS             8771..9337
                     /locus_tag="PC466_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDF2768713.1"
                     /translation="MATRPIEIDEYKKIMELLHTGFTYSENGVEKRFRKNPKVALALM
                     LEANLGLRISDILRLKIGNFKGNMLEINEKKTGKLQYRPVNKNIIESINEHARKYNLK
                     SNDYLVNIKTKAIQKQLRIICKHLNLYNISTHSFRKLYATTQFEKSNNNLELVKELLN
                     HSSVATTQRYIRVTQQAINEASENFFIG"
     gene            complement(9538..10743)
                     /locus_tag="PC466_001322"
     CDS             complement(9538..10743)
                     /locus_tag="PC466_001322"
                     /EC_number="1.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HDF2768714.1"
                     /translation="MKIAILGYGTVGSGLIDLIENNTSKRDIEVVGILVKNKEKHKYK
                     KYFDKITTDIEDIFDKDIDILVEVIGGLNPAFDYVTRALNKKIHVVTANKDLLAEKGS
                     DLIELANLNNVSIKFEASVAGGIPVLKPLIESLEGNNIKSINAILNGTCNFILSKMYD
                     ENLPYDVALKQAQELGFAEVNPDADVLGYDSARKLSILSTLSYGKIVYWKDLLLEGIT
                     SIDEKDIEYAKKLNCKIKLVARSKYESGEVSGFVRPALVDNNNMLSKIDNEFNVVILV
                     GDSVGELSFVGKGAGRGATGSAVYADIIDIIDNRSSNIKSFSKGKLDLSGLIEDECSA
                     VVRFGGYNNKDGILECLDKYVDSYDIIDDEELAIFVSAKSEHEIDRVLEIVKRNNYSE
                     SAKKLLKID"
     regulatory      complement(10846..10952)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            complement(11044..11412)
                     /locus_tag="PC466_001323"
     CDS             complement(11044..11412)
                     /locus_tag="PC466_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhbY family RNA-binding protein"
                     /protein_id="HDF2768715.1"
                     /translation="MLKGKQRAYLRSLANTLKPTTQIGKEGVTESFLEQLDGMLRTRE
                     LVKVTILENAGLDTKETANAVCEALRAEFVQAIGFKFTIYKRNIEEPKILFPGHEQAK
                     AKTKNNNVTKKGKPTKRAVR"
     gene            complement(11464..12741)
                     /gene="obgE"
                     /locus_tag="PC466_001324"
     CDS             complement(11464..12741)
                     /gene="obgE"
                     /locus_tag="PC466_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000469293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HDF2768716.1"
                     /translation="MFIDKARIFVKAGNGGNGSVAFRREKYVPAGGPDGGDGGRGASI
                     IFEVDLGLRTLMDFKYQKKYQAQNGGDGSKGKRAGKNGENLVLKVPAGTVIRDEATGL
                     VLADLKKEGDTAIVAKGGIGGKGNQHFANAVRQAPAFAKSGTDGEERWITLELKMIAD
                     VGLLGFPNVGKSTFLSVVTKAKPKIANYHFTTLTPNLGVVQTKFGDSFVLADIPGIIE
                     GASEGIGLGHEFLRHVERTKVLIHIVDISGLEGRDPIEDFDKINDELKLYNEKLSKRP
                     QVVVANKFDILEDESKFEKFKSELEGRGYTVFKMSAATRQGIDEVIAYVSKMLKEVED
                     VELVSEEEMYRPELDIGTEEELSIDIEDGVYVVTGKALRRIMYSVNFDDMESLQYFQK
                     AMESQGVFDRLREMGIEDGDVVKIYELEFEFYN"
     gene            complement(12852..13142)
                     /gene="rpmA"
                     /locus_tag="PC466_001325"
     CDS             complement(12852..13142)
                     /gene="rpmA"
                     /locus_tag="PC466_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HDF2768717.1"
                     /translation="MLNMNLQLLASKKGVGSSKNGRDSISKRLGVKRFDGQLVTAGSI
                     IVRQRGTKIHPGTNVGKGSDDTLFALVDGTVKFERKDKKRKKVSIYPVAIAE"
     gene            complement(13156..13473)
                     /locus_tag="PC466_001326"
     CDS             complement(13156..13473)
                     /locus_tag="PC466_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HDF2768718.1"
                     /translation="MIKVKYYYNDDFLLQGFCLKGHADFAEIGYDIVCAAVTSNAIAV
                     INSLDKLQKIEFEKVVGEEGHIECIVKDTHVKDAQLLLNHFQLAVKEIKREYPKNIKI
                     LKK"
     gene            complement(13488..13799)
                     /gene="rplU"
                     /locus_tag="PC466_001327"
     CDS             complement(13488..13799)
                     /gene="rplU"
                     /locus_tag="PC466_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012063435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HDF2768719.1"
                     /translation="MYAIVKTGGKQYKVSEGDVLFVEKLEANAGDVVTLNEVLACSKD
                     GELKLGSPVVEGASVQAKVVEQGKAKKVIVFKYKAKKDYRRKQGHRQSYTKIVVEKIN
                     A"
     gene            complement(13900..15321)
                     /locus_tag="PC466_001328"
     CDS             complement(13900..15321)
                     /locus_tag="PC466_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rne/Rng family ribonuclease"
                     /protein_id="HDF2768720.1"
                     /translation="MKKIVIESLIGSQKTAVLEDERLTELFVEDNLNKKTVSNIYRGI
                     VKKVIPGIEACFVDIGFKKLAYLQLKKGSTIKSGQDILVQINKEEIGTKGAKLNTEIS
                     ISGRYIVYIPSNDRTTISNKITDEKERFRLKKITKAVNKENLGLIIRTEAQGCTHDEI
                     KKDIEELKLKYENILKEYKLGIGPKLLYKSLDFATKYVKDNVNDDIESIITNSYDKYS
                     ELKSILRGIDKTYVDKLCLEENRDVFDLYRIESKIEKLLNKKVWLKSGGYLIIEKTEA
                     LTVIDVNTGKFIGTGKLDETVYKTNLEAAKEIVRQLIIRDIAGIIIIDFIDMHKKKHQ
                     KEILHILEEEFNKDKRKAEVLGMTKLGLVEVARRREKESIDKYYLMSCPCCDGEQTIK
                     SVHYILDSIEKEIMRISEHTVYKNIMVEFNDFIFEQIKEYYMDIIDKIGEKYNIKISL
                     NANSTLKHNKTNVIFDKIVDNKM"
     gene            complement(15339..16040)
                     /locus_tag="PC466_001329"
     CDS             complement(15339..16040)
                     /locus_tag="PC466_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2344 domain-containing protein"
                     /protein_id="HDF2768721.1"
                     /translation="MSKIIRVKFKKEGDMIYISHLDLQRLLQRAFRRAEINLSHSQGF
                     NPHPKMSYGNALALGTESQGEYVDIEIEEDDLSVEEFLNKVSIQLPDGIDFIKAKEID
                     RQTPSLSSVIDYGEYLFNIDLKRPMTKEFVKRKVIDFMNNKEIIITKKNKKGKMVEVD
                     IRPMIRTFDVLNLEDEHITLTATIATGSKTNLNTNILIPKILEMFELDIDPLDVDILR
                     RDLYVLEDGELVTPM"
     gene            complement(16042..17886)
                     /locus_tag="PC466_001330"
     CDS             complement(16042..17886)
                     /locus_tag="PC466_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03960 family B12-binding radical SAM
                     protein"
                     /protein_id="HDF2768722.1"
                     /translation="MNKVDLKKILKKVEKPARYLGNEINSIHKDTSNSELIRYAHCFP
                     DLYEVGMSHLGSHILYDVINKDEDVFCERVYSPAVDMENIMREKSIPLFALESREPIT
                     NFDFVTFTLQYELSYTNILNILDLANIPILKEERTLEDPFIMVGGPCAYNSEPLADFI
                     DVVILGEGEEVNLEVVNEYKEWKKNKTTREDFLYKISSIEGVYIPSFYDVKYNEDGTV
                     QSVTPNREGITKNPTKRIIKDVETVDYPEKLIVPYIDTVHDRIVLELFRGCTRGCRFC
                     QAGMIYRPIREKSVKRLKEILDKLVKNTGYDEISLSSLSTSDYSKLSELTDYLVDEYA
                     SNNIGISLPSLRLDNFSMEIADKIQQVRKSGLTFAPEAGTQRLRDVINKGVTEEDLEN
                     ATERAFEMGWNSVKLYFMIGLPTETYEDLDGIAKLAYKVIDIYRKVNGGKLKRSFSVT
                     VSTSTFVPKPFTPFQWHGQDTTEEVINKQRHLVNKLRNNNIKYNYHDSKTSLMEAVVA
                     RGDRRIGKVIYDAFRLGAKFDGWAEHFNLDIWKEAMEKNNLSIDFYAHRNRNYEEVFP
                     WDHIDVGISKKFLIREDENAKKEKITSDCRHNCNGCGINIHDIGRGLC"
     gene            18205..19398
                     /locus_tag="PC466_001331"
     CDS             18205..19398
                     /locus_tag="PC466_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FprA family A-type flavoprotein"
                     /protein_id="HDF2768723.1"
                     /translation="MSKVFEVKKDIYFTGVVDEGLKVFDIIMETEFGTTYNSYLIKDE
                     KTVLFDTVKANFKDEFLSNLSEVTDIAKIDYVVIHHTEPDHAGSLKYLLDINPNIEVY
                     CTKAAKLYLDGQINRPFNCHVIKDGEILNIGKRNLRFITAPFLHWVDTMFTYIEEDKT
                     LLTCDAFGCHFASVDAEVVNSEDYLKSAKHYYDCIVKPFAKHVLSAVDKVVGLNIEFD
                     TILTSHGPMLTKDPMAAVKRYVEWSTEAVNTTNQNQVSIFYLSAYSNTLEMAKKIKEG
                     LDKEGAKAELYDLEDMTLTEMHDTLVVSKVILLGSPTINKTMVKPMWDLFSVIDPMAN
                     QGKIAGVFGSFGWSGEGITMAETLLKSMSFKMPVESLKKKFFPSEETLKECMAFGAEF
                     AKLVK"
     gene            complement(19610..20692)
                     /locus_tag="PC466_001332"
     CDS             complement(19610..20692)
                     /locus_tag="PC466_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="HDF2768724.1"
                     /translation="MKKIRKLATKLLIATMVLTSCMSVTVYGMTAKDVTAKTPKSYVA
                     GTNSIYGPKLSQAQLNSVAQATADFMNKKITKNMTTDAKIRVAYNHIKNNTTYVNWNA
                     AEGANTAYTLVTKKGACSGMCRSLKALCDAMGIECYYVHSTTNDHQWNLIRFEDGRLY
                     HVDIDANKSAGADIIYKSLTHPLPFDKKAYPAVGESVKTQNPTPTVKKPTPAKPSAPV
                     GPGNHTMIADQEEAILDEVYGNNLRPKIERYEGVPCSLINSSINTIKFTSKNSNLDPS
                     RHTVSVIGFMNTPYGMVALAPDGVPVEYPFEYDKPFSLDFTGKNLSAAELSKKCKNNN
                     VIIKIEIGEIEPNSGRGQVRYARYVN"
     gene            complement(21256..22047)
                     /locus_tag="PC466_001333"
     CDS             complement(21256..22047)
                     /locus_tag="PC466_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768725.1"
                     /translation="MKLIDEYLDKLYKKCDNKSTIELKQEMRCHLIESANEFKLEGLD
                     EEEACKKAIERFDDGDEMQYELCNIIKELSLSLDRHKSIVMGFKKVLGYISIIAFLIS
                     GFMWYYNNSLQHNMYNLGKELDGEIKQLAERHDMTNIGEYKLELEKILDKDKYSKVKA
                     LRLYVIDMKDGNTNLSSSGLNANMVYEREADYNNISNFIQHLGYNGKDFLDKNGNIVN
                     PDIFLEYFFYFESEMLIPVAFAFGLLCIIAYFILRFKISLIKNNN"
     gene            complement(22051..22380)
                     /locus_tag="PC466_001334"
     CDS             complement(22051..22380)
                     /locus_tag="PC466_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2768726.1"
                     /translation="MQLNKEVLKGYIDILIVSILEKKDCYGYEIAKQVRERSEFELKE
                     GTMYLALKRMESKNLIKSYYSNEQSSGGRRKYYNLTNEGKDFLEIKKQEWRFIKKVMN
                     QFLGEVD"
     gene            complement(22865..23278)
                     /locus_tag="PC466_001335"
     CDS             complement(22865..23278)
                     /locus_tag="PC466_001335"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HDF2768727.1"
                     /translation="MNIALVAHDQMKNTMVGFCIGYESILKKYGLYATGTTGKRIMDE
                     TELNINRLASGPLGGDQQIGSLIVTQEIDLVIFLRDPLTSQAHETDIQALIRLCDVYH
                     VPIATNLASAEIFIKALDRGELSWREVRKSKSQRI"
     gene            complement(23319..24449)
                     /gene="rodA"
                     /locus_tag="PC466_001336"
     CDS             complement(23319..24449)
                     /gene="rodA"
                     /locus_tag="PC466_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein RodA"
                     /protein_id="HDF2768728.1"
                     /translation="MKKININYKSTIKLIKQLDWKLIVTVLAIFIFGLVILSSATHAN
                     STGSYNQLIKQGLAFVLGIGMIIVILFFDYNLLGRYYKALYIISLILLAIVLLPGIGT
                     VKGGARSWINLGPLDLQTSEIVKLTFVLSYAKILESKKDKLNTLKEVMPVVVYSLPFI
                     GLLIAQPDLGTGIVFCCMIFAMLFTAGLSSKLIKRGIIILLVSMPLMYLMMADHQKVR
                     IEAFLNPEDVTLKGNYQVMQSLIAIGSGGVTGKGLYNGSQNQEDFLPVQDSDFIFAVV
                     GEELGVIGMAVLIILFMIFLLRLLAIARDAKDFYGTLIVVGVMGMFGYQIIQNIGMTV
                     ALIPVTGVTLPFVSYGGSSLLTSLANLGLVLNVCMRRKKINF"
     gene            complement(24534..24818)
                     /gene="minE"
                     /locus_tag="PC466_001337"
     CDS             complement(24534..24818)
                     /gene="minE"
                     /locus_tag="PC466_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division topological specificity factor
                     MinE"
                     /protein_id="HDF2768729.1"
                     /translation="MLDLFRVFSNEAKTSKSVAKERLKLVLVHDRVDCSPQLLEMIKT
                     DILKVIANYAEIEDDGLEIKMSKCRGEHDDKPVSALVANIPLKNIKDRCM"
     gene            complement(24836..25633)
                     /gene="minD"
                     /locus_tag="PC466_001338"
     CDS             complement(24836..25633)
                     /gene="minD"
                     /locus_tag="PC466_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum site-determining protein MinD"
                     /protein_id="HDF2768730.1"
                     /translation="MSEVIVITSGKGGVGKTTTAANLGTALSLENKKTVVVDADIGLR
                     NLDVVMGLENRIVYDIVDVVEGTCRLKQALIKDKRFDNLYLLPAAQTRDKNAVSVEQM
                     IDLCEKLKESFEYIIIDCPAGIEQGFKNAVAGADRAIVVTNPEISAVRDADRIIGLLE
                     ANEIKEIRLVINRIRNDMVKRGDMMDKQDIIEILAIDLLGLVPDDESIIISTNKGEPA
                     ILDSKSLAGQAYKNIAKRILNEEVPLLDLEVEDGFFGRLKKMFSMAK"
     gene            complement(25657..26340)
                     /locus_tag="PC466_001339"
     CDS             complement(25657..26340)
                     /locus_tag="PC466_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum site-determining protein MinC"
                     /protein_id="HDF2768731.1"
                     /translation="MSLREICSQELVEFKGNKRGIIVNIKREAPFEEIQEKIINKLEA
                     YVGFFNGAKISKINSDCLTDMEILELKEGITSRFDVEFVEDQKIEENSNFPTKYVNTL
                     RSGENIEFEGDVVILNDMKPGSKVLSKSNTVVMGDINAGAKVVAGGNVFVMGKIEGFV
                     HAGAEGNEFAYVVAGNLNPKILQIADNIAEAPDDEENYENESEISPEIAFVSNGRIVI
                     ESYLSKLDK"
     gene            complement(26438..29416)
                     /locus_tag="PC466_001340"
     CDS             complement(26438..29416)
                     /locus_tag="PC466_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HDF2768732.1"
                     /translation="MEENKQVDRLKIIKIVMSVIFLAILVKIIYMTTFKYEYYNELAE
                     NKTYKKLAIEAPRGEIKDRYGRLLAGNKNLFTVQVSGNDINKKDANKHSRANEISLKL
                     INLLERNGEEYVDEFPIYVENGKYYYTYDRDIREYKSENGIPNDYNAKESFYYLVDKL
                     ISAGILSQEDKRLDATRLQAKLNENGYYPPILVSKWMFTAERDKRDWLASYKIKETKL
                     SAKEAFEKVRNSDALEIDKSLSDEDARKIMVVRDLIKSKGYSQYNPVTIAKDVGETTI
                     AQIEESAMDLVGVSIAVEPVRYYPNGSLASHMLGYVGKMPSTQIESYLQKGYETGDMV
                     GLAGVEKSNESRLRGTDGYKMVKVDALGRISKEIESKKPKSGDTVYLTLDKDLQEVSD
                     NALKQIIEVASKGGTFKSKFGDKPISAYAGKAQSAALIAIDVKNGEVLASSSYPNYDP
                     NKFAKGISTEDYKALQPKNPNDLLAGSPLLNLVTQGEFQPGSSFKMLTSMAALENGLD
                     PNFTINDPGVIMLGKKSFGDYVWNHGRGNHGMTNLYKAIQESCNIYMATIGTGKTWPD
                     GKSIGIDMNANKILEYAKLFGLDQNTGLQDEVEERAGKVPSTEDKLKSTQALLKSNLE
                     REMANDFVDITREKNPKEYEKRINEIVSWAAEKKTPGRVETMNRLKKMNVKEDRIEEV
                     ADLAVFSYFNFAKWSTADTFNLAIGQGENAYTPAQISRYVAAIANGGNLVELSVVDRA
                     VSSDYSSVKINDQKKVEKIPFKNPDNLKELTKGMKLVARQGTAKSAFADFPIDVAAKT
                     GTAEKSGKIPTDNEYEYLKSHMSSYNVNLNDAIKLADKMKAEKEKELSLAKEKEIKKK
                     LENKDLKDEERKKLEEELEDGVKVRLEDTDKVNSSYLRKAIKELNPKITDDQIDRFKQ
                     DYGSFTWTVAFAPADDPEIAVVCVIPQGDSSVFSLLPTREVIGTYMGLEPTNSKNDNK
                     TNDVNNSSDENINFESQINR"
     gene            complement(29428..29916)
                     /gene="mreD"
                     /locus_tag="PC466_001341"
     CDS             complement(29428..29916)
                     /gene="mreD"
                     /locus_tag="PC466_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HDF2768733.1"
                     /translation="MKKVLLCLLGIVLMTIENSITNYIDIFGISFNLVLIYVTIISLY
                     LDELEGGIIAAIIGLIKDITVGGIFGVNALILFIIAYAIGYMRDQLYKGSYIITFVLI
                     FIGSLIDSIVNIGTSSIIYQSYNISTLFVKGLLVAPIVNSLIGLVIYRLSKRAVLKLK
                     ED"
     gene            complement(29931..30824)
                     /gene="mreC"
                     /locus_tag="PC466_001342"
     CDS             complement(29931..30824)
                     /gene="mreC"
                     /locus_tag="PC466_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HDF2768734.1"
                     /translation="MALRFDKNKNEKKRINVKVIATGVVAITLIGIVGISIGKFSSGS
                     PVNLGVASDAITSVGKGINDGFSFIKNGFKDVANFKDNSKKVKKLEEENEKLKKDMIA
                     LNAKLDKTESLEELKKTLNFVQEEYKATSISASVVGKNDGNWYESFVIGAGKNSGVKK
                     ESIVMNGSGLVGIVYEVSNNYSKAISLLDSKASVSFKLAKDANAKGTITQNTTLDNKD
                     SYNSKGYLQGYMFDSSYNVIQGDIITTSGLGFFPDGIPIGEVEKVVDDKDKSLKYVVV
                     KPYVDFKNINDVVVIEPRNIG"
     gene            complement(30834..31844)
                     /locus_tag="PC466_001343"
     CDS             complement(30834..31844)
                     /locus_tag="PC466_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein"
                     /protein_id="HDF2768735.1"
                     /translation="MTKDMGIDLGTANTLVYIKGQGIVVREPSVVAIRDDSKEVLAVG
                     EEAKKMIGRTPGNIVAIRPMKDGVIADFDITQSMISYFIQKAADKKGVVSPRIAICVP
                     FGVTEVEKRAIEEAARQAGAKDAFLIEEPMAAAIGAGLKVEEPEGNMVVDIGGGTSEI
                     AVISLGGIVTAKSIRIGGDEFDESIVAYVKKEYNLMIGERTAENVKINIGSTFKDDEE
                     INMQIRGRDLISGLPKTIEICSTEVREALKEPVSSIVDAIKSTLERTPPELASDIMEN
                     GIMLTGGGALLRGLDKLITQETGMSVQIAETPLDCVALGTGKSVEDQEIFEKVLMMNT
                     KN"
     gene            complement(31965..32624)
                     /gene="radC"
                     /locus_tag="PC466_001344"
     CDS             complement(31965..32624)
                     /gene="radC"
                     /locus_tag="PC466_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HDF2768736.1"
                     /translation="MAPEERPREKMLAKGVKSLSNAELLAILLRTGNKNKNAIELANY
                     IINRDIQGIRHLEDMTIEELCNIDGIGLSKSTQIKAALELGSRVASFKPIKYKIRNPW
                     DIQRYYMDSLRYLKKEVFKAVLLNTKNEIISDVDVSIGTLSSSLVHPREVFKEAIRRS
                     ASKIIVMHNHPSGSVEPSREDKNITSRLIKCGEIIGIEIIDHIIIGDGLYFSFKENMI
                     I"
     gene            complement(32669..33253)
                     /gene="maf"
                     /locus_tag="PC466_001345"
     CDS             complement(32669..33253)
                     /gene="maf"
                     /locus_tag="PC466_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation inhibitor Maf"
                     /protein_id="HDF2768737.1"
                     /translation="MNIILASASPRRKEILENTNVRFDIIKNEIDEIILEGETPKHLV
                     MRLAFEKSMSVASEHNEDVVIGADTVVVLDNAILGKPKDESCARDMLKRLSGREHQVI
                     TGISLINLCEDKKVIDYVISNVKFKTLSEQDIEDYLKTNESFDKAGAYGIQGYGALLV
                     EEIRGDYFNIVGLPISRLGDLLKKYFSINLFYGV"
     gene            complement(33473..34444)
                     /locus_tag="PC466_001346"
     CDS             complement(33473..34444)
                     /locus_tag="PC466_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit B"
                     /protein_id="HDF2768738.1"
                     /translation="MVILTAVLVLGIMGLIFGIVLDFASKKFAVEVDERVEAILGVLP
                     GANCGGCGFPGCGGLANAIVEGNAPVNGCPVGGADVGAKVGEIMGISAEAGEKQVAKV
                     ICKGTCSSAKDKYEYEGISDCRAANVLNSGAKMCKFGCLGLGTCKDACKFDAISIVDG
                     IAVIDEEKCVNCGKCKEVCPKGIIITKPESQEVVVECNSKEFGKAVKEKCTAGCIGCG
                     MCVKACKFDAIIFEDKIAKIDPNKCVGCMQCVAKCPTKVISGDITKKKKVTIDQELCV
                     GCTVCKKQCKFDAIEGELKEKHKVDADKCVGCHLCMEKCPKKAIKIL"
     gene            complement(34460..35035)
                     /gene="rsxA"
                     /locus_tag="PC466_001347"
     CDS             complement(34460..35035)
                     /gene="rsxA"
                     /locus_tag="PC466_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxA"
                     /protein_id="HDF2768739.1"
                     /translation="MNLILLFLSIVLVNNVITSQFLGICPFLGVSKKVDTAVGMGVAV
                     TFVLTLASIITYFIQILLVKTGTGFLQTIAFILVIASIVQFVEMVIQKMSPSLYQALG
                     VYLPLITTNCAVLGIALVNVQKSYNLVETIINGFGAGAGFTLAIVIFAGIRERLELAD
                     IPEAFKGFPITLISAGLMSIAFLGFTGLIKL"
     gene            complement(35050..35643)
                     /locus_tag="PC466_001348"
     CDS             complement(35050..35643)
                     /locus_tag="PC466_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit E"
                     /protein_id="HDF2768740.1"
                     /translation="MNLAKVFKNGLIDENPTFVQVIGMCPTLAVTTSAINGIGMGLST
                     AAVLICANLVISLIRKITPDKIRIPIFIVVIATFVTIVGMLLKAYVPALDKALGIYIP
                     LIVVNCLILARAESFAFKTGAMPSIVDGVGQGLGFTVALTIIGAVRELLGNGSLFGMT
                     LFGASFQPVLIFILPPGAFLTLGFLFAGFNKLRSKKA"
     gene            complement(35656..36225)
                     /locus_tag="PC466_001349"
     CDS             complement(35656..36225)
                     /locus_tag="PC466_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit G"
                     /protein_id="HDF2768741.1"
                     /translation="MNSMVRLGGTLLAISAIAALALGATNQVTAPVIEQRNIQENNEL
                     RKAVLPEAKEFKEMDKSTYKDLGDGLIAEVYEGLDGSEVVGYTLKAKPSGYGGEIEVM
                     VGISSEGQVTGVDIGNMSETAGLGAKAKDDAFKGQYKGKTAEPLEVAKGSTTADNQIL
                     AISGATITSTAVTTGVNAAIDVFNSALNK"
     gene            complement(36225..37202)
                     /locus_tag="PC466_001350"
     CDS             complement(36225..37202)
                     /locus_tag="PC466_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit D"
                     /protein_id="HDF2768742.1"
                     /translation="MENKLIVSSSPHVRSNEDTSYIMKQVIIALLPAAVAGVYFFRLN
                     ALSAMFFCILGTVGTEFLYQKFTKQKSTIGDFSAVVTGLLLAFNVPASLPWWMCLVGG
                     IFAILVVKMVFGGIGCNFVNPALAARAFLLASFPVAMTAWTQPGVNWIGKNLDAVTTA
                     TPLSFLKNGAAGLADLSSNGISLADMMIGNIGGCIGETSAILLLLGGVYLMYKGIINY
                     VIPVFYIATVFILTFLLGGFNITFAIYQLFAGGLMLGGFFMLTDYTTSPMTKKGQIIY
                     AVLAGLITTVIRMYGGYPEGVSYSILLVNCLAPLIDKFVRNRVFGEVAK"
     gene            complement(37225..38562)
                     /gene="rsxC"
                     /locus_tag="PC466_001351"
     CDS             complement(37225..38562)
                     /gene="rsxC"
                     /locus_tag="PC466_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxC"
                     /protein_id="HDF2768743.1"
                     /translation="MKLLTFKGGIHPPYRKEYSNTKALEKAQAPKIVYIPLQQHIGAP
                     AKPIVEVGDEVKFGQKIGEQQGFVSCNVHSSVSGKVIAIEQHEVPGGSAQCVVIENDF
                     KEELHESVQPKGQLEDLSKEDIVGIIKEAGIVGMGGATFPNHVKVSPPPDSKAEVVIL
                     NGAECEPYLTADHRLMVENPEDVVFGLRALMKVLDVKKGFIGIETNKPDAIEAIQNVA
                     KDYSEIEVVGLQVKYPQGAEKQLIYACTGKEVPSGGLPIAAGAVVDNVATAAQIAKSI
                     KTGMPLVERITTITGSCIKEPKNLITKVGTLVSEIIEQCGGFKEDKKIGKVIMGGPMM
                     GIAQYTTEIATNKGSSGILCLDEEESRTPDIQNCLRCGRCTDVCPSFLQPLFISAYSL
                     KDDYDTAEYHRAMDCIECGSCSFICPARRPLLQSIRSAKREIGAKRRKQAAQK"
     gene            complement(38778..39722)
                     /locus_tag="PC466_001352"
     CDS             complement(38778..39722)
                     /locus_tag="PC466_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768744.1"
                     /translation="MNRRKTIYRGFNNNRHKIDLRKYVITIACLCLIGYYSYTKIKDS
                     KILEYVSAKIPFLNNSSDITYKDISDELNSIKKGKKSKSQTNSDDKQETNPEKAVNNT
                     KEPEEVKLATIEGWDMYTIQVAAIDNNDDLKKIQTSLVNNDIPFSVMEKDGVKKIQTY
                     SSFDENDVRKQISSVRKVFPDAFLSHLDAPMLSLEYTSNYAYIESISKELNKLITNFK
                     EESSFWSNAENNVDMEKYNTILTNRKAISQNISKEAEKIDYSEMRLFKDNLIEYVKNV
                     NEKIDTASKAANEEKYSVSKSLLLSSMQEYSMFINSIK"
     gene            complement(39833..41107)
                     /locus_tag="PC466_001353"
     CDS             complement(39833..41107)
                     /locus_tag="PC466_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HDF2768745.1"
                     /translation="MKKAIAALGIGAVAVSVSSINASALEKGTVTASALNIRSGPSSD
                     CDKVAKLYKGKTVEILEKSNGWYKVRVSSSVVGWGSAKYISTSGSSEGTSNQNNPTSS
                     GTTISGNGKVNVSSRLNVRSGAGTNYSLVGKANNGDVVKLLEQSNGWYKIKLSNGVTG
                     WASSQYISKTSEDVGTNNSSNSNSTNNSDKKPSSEESIEGKNGKVTSAVSLNVRSGPG
                     TSYSIIGKLNGGDVVELKSKNNGWYKVKLSSGTIGWVSASYISETNEGTKEKPNSSSN
                     QNSQSNSNSKPSFTGNSDKSTAKGSTIVDFAYTLIGIPYQWGASGPDKFDCSGFTQYV
                     FKHSVGVSIPRVSREQANFGSAISMGNYAPGDLVYFDTDGDGTTNHVGIYVGNSKFIH
                     CSGTQTNPNKVKVDNLTSSYWSKVLLGARRFV"
     gene            complement(41239..41610)
                     /locus_tag="PC466_001354"
     CDS             complement(41239..41610)
                     /locus_tag="PC466_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDF2768746.1"
                     /translation="MKFNFCHNNFNVTNLEKSLDFYKKALGLKEVKRKEAEDGSFILV
                     YLGDGITSHTLELTWLRDWDRPYNLGDNEFHLALEVEEFDEAKKLHKDLDCICFENES
                     MGIYFIADPDNYWIEILPKNH"
     gene            complement(41838..42437)
                     /locus_tag="PC466_001355"
     CDS             complement(41838..42437)
                     /locus_tag="PC466_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768747.1"
                     /translation="MESRGYKEDLKKMILDMAHKELESYVSQKGAKKYFEGNLDKIIN
                     NNIKKFNQSIGLNRVYLKMLKKCAYQESVTSISRTIKKEALFKSKKELFAFSEYLKLD
                     INKRLSYNQILRKISRYIYYNRSSYAQKYVVFKRGDEEYLLEPEKIKDELISSYRSKT
                     REDMRSIAKLLDIEVEDDYNAEDIRKKVINYIIKEKLKS"
     gene            complement(42638..42850)
                     /locus_tag="PC466_001356"
     CDS             complement(42638..42850)
                     /locus_tag="PC466_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy-metal-associated domain-containing
                     protein"
                     /protein_id="HDF2768748.1"
                     /translation="MKKKLLVEGMSCGHCVNHLKTALTEDIDGIEVLDVDLENKCASV
                     DMKDDISIEKLKEVIAELGFELKGIE"
     gene            complement(42923..44638)
                     /locus_tag="PC466_001357"
     CDS             complement(42923..44638)
                     /locus_tag="PC466_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF2768749.1"
                     /translation="MKRIKVLTVVLAITLMVAGCSNTKTKQSSSDSSLQSQSSIDAKY
                     INLTMVTPKTINPITNTDKSVGYIMNLVYDSLFTIDENYNVIPQLVKEYNIAQDGMSI
                     DIKLKDAKWHDGKNVTSNDVNYTIGLIQKSADSPYNEFTKNIASVNIKSDKDFTIKFK
                     ARYAFSIDSLIFPIVSQNHLDSKDVNDKNNNMIGNGKYKIESYTEREGMVLSVNKDYY
                     EEVPKTMKNIKVGMVPNEEARTSMVMALDSDITNVTLNDLSKFQEKEFNITKYQGRDY
                     ECVLFNYNNPFFKDVNFRKAIAHSIDKDRIISEGYMDDATPVNFPLNSKSKYYNSEMK
                     DLEFNKDKAIECLAKVEYANINSVNQNDNKVKNQKKSAKKNSKKLTPEEEAKAKKAEE
                     DRIKKEAEKKKNREKEEVKKSLSEMNLKIIVNRDNSERIKTANIINENLKAIGINSTV
                     NQLSDKDMENALNSKNYDLALVGWKLSIIPDASSIIASSGYTDDKLNGYMSALTSSTS
                     EIETKKAYKDVQTYIKDNATFISLAVRNNYIVSNSRLKGKITPNDFDVYEGISNLDIK
                     SNESN"
     gene            complement(44638..45192)
                     /locus_tag="PC466_001358"
     CDS             complement(44638..45192)
                     /locus_tag="PC466_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HDF2768750.1"
                     /translation="MNSKKVLILSIFIILFGALLMESKVIHKFLYPKKYSEYVEKYSK
                     EFNLDENIVYSVIKAESKFNSSAVSKKEAKGLMQILDITRDWGAEELNLKNVDIFDPE
                     TNIRLGCWYLSKLYKEFGKLDLVIAAYNGGSGNVKKWLENNEYSKDGENLHDIPFKQT
                     SKYVEKVKNNYEHYNKIYGKKGKN"
     gene            complement(45185..45787)
                     /locus_tag="PC466_001359"
     CDS             complement(45185..45787)
                     /locus_tag="PC466_001359"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HDF2768751.1"
                     /translation="MLILGLTGGIGCGKSSLSNIFRNLNISIVDADIISRKIFEDKLL
                     LEKVFVHFGQSIKNDDGTLNRKALGKIVFSDEEKLKELNSLTHPRIREKIISEIEELR
                     KKGENIVVLDAAILVESGFLDMVDKLLVVTCKQEVQISRIQKRDNCSKQEALSRINSQ
                     MSQEEKSKYGDYIIDNSGTITELESKAHKFIEYMKENWRE"
     gene            complement(45796..48444)
                     /gene="polA"
                     /locus_tag="PC466_001360"
     CDS             complement(45796..48444)
                     /gene="polA"
                     /locus_tag="PC466_001360"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HDF2768752.1"
                     /translation="MEKKLIIIDGNSIINRAFYALPEMNNKEGLKTNAIYGFTTMLFK
                     MIDIYKPTHISVAFDRKAPTFRHLEYKEYKAGRKGMPDELAEQLQPLKDLLDKFKINR
                     LEIDGYEADDIIGTVSKKAENNGYKVYIVTGDKDAIQLASDNTTTLITKKGVGEVEEY
                     NFNSVIEKYEMTPAQFIDLKGLMGDKSDNIPGVPGIGEKTGIKLIKEFSSIENLIENT
                     DKLKGSVKKKIEENKEIAIQSKRLATIIRDVPIEVDLDSMVFGDYDKDELLDKFRYFG
                     FTSLLSRLVDLVDSDDTEHVEEKIEILKLKDTEKFIDEVNKKGQVILKTVRGQGNILE
                     KNIIYIFISVDGEKIYYVDSNEVSKLDSIFSNNEIKKYGYNLKDDYISLKPYNINLEN
                     MYFDITIAEYLIDSTSSTSYDCSAIAMKYLSKKVKSKEELLGKGVKSKNYEDLEFEDL
                     AEYMGQIICTVKETIPMMERSLMDMSMDGLFYHVEMPLVEVLGHMEYEGIKVDKSILD
                     ELSVEFKEIIATLEKEIYELSGEPFNINSPKQLGVILFEKLELPIIKKTKTGYSTNAD
                     VLEKLRDKHPIIDKITEYRQIVKLNSTYVEGLLNIINPESNRIHSSFNQTITTTGRIS
                     STEPNLQNIPIKMEMGRKIRKVFIADDNCKLVDADYSQVELRVLAHMSQDENMIEAFK
                     HHEDIHTKTASQVFNVPMEDVTSELRGAAKAVNFGIIYGKSDFGLADDLNIPVPKAKE
                     YIESYFAKYHKIKEFMDTTVEKASEDGYAVTILNRRRYIPEIKSSNFMERNRGKRFAM
                     NAPIQGSAADIIKIAMINVHKKLEENNLKSKLILQVHDELIVEAIDDEIDIVKKIVKE
                     EMENAVNMDVHLDVDLNVGSSWYETK"
     gene            48763..48845
                     /locus_tag="PC466_001361"
     tRNA            48763..48845
                     /locus_tag="PC466_001361"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:48797..48799,aa:Leu,seq:caa)
BASE COUNT        15367 a         9163 c         5484 g        19415 t
ORIGIN      
        1 aaaataatta aagataaaag gagtatttta tgaacatact tggattaata gttgaatata
       61 acccatttca taatggacac atatatcatt tatctaaatc tatagaaaaa acaaatgcaa
      121 cacatactgt agcaataatg agtggaaatt ttctacaaag aggcgaacca gctttatttg
      181 ataaatatac tagagcaaaa attgctgtcg aaaatggtgt agacttagtt atagaattac
      241 caactttatt tgcttgtcaa agtgctgaaa ttttttctca tggtgctata acaattttaa
      301 attcactaaa ctgcataaat tctatatgtt ttggtagtga agaaggaaat acagaaattc
      361 tttataatat agctgaaatt ttagcaaatg aaccaaatga atttaagtta cttttaaaaa
      421 aatatttaga tgatggcctg ttatttccaa cagctagagc taatgcactt tttgattata
      481 tacatcaaga caaaaaaaat aattttatac aaaattattc aaaggaacaa ttatcaaaaa
      541 cattaaattc atcaaacaac atactgggta tagaatacat aaaaaacctc atccatttaa
      601 acagtagtat aaaaccattt actatctcca gggtccaatc agaatataat tccgaagaaa
      661 ttgagagtga tatttgttct gctactgcta taaggacttc acttaaagaa aatacagacc
      721 tttttcattt aaaaaatgtt attccagaaa aaacttataa catcctaaat gaaaaagtag
      781 ataatggttt tttacctatg tttgatgact tcttctttga tattttaaaa acaattatac
      841 ttagagatat ggacacttta aaagagtatt ttgaagtaaa tgaaggcata gaaaacagaa
      901 tctataaaga tatctttaca tctgaatttc tacatgagct acaattagca attaaatcca
      961 agcgatacac tttaaccaaa atcaaacgaa ctctaaacaa tatattgtta ggtattaaaa
     1021 aaagcgacat gcaacttata aaaaacatag atactatacc ttatataaga atacttgctt
     1081 ttaatgataa aggtagagaa attctaaaag agataaaaaa taaatctgaa ataaaaataa
     1141 taaacaagtt ttcaaatata tcattttcat tagatgatac gatttttaaa acactcataa
     1201 gttatgatat aaaagctaca aatatatata attcaatata ttataaaaac aataaagatt
     1261 tagtaaaagg ccctatggat ttttatactc atccaatata tgtaaagtag ttttttaaaa
     1321 taactatatt tataaaaatc attttattaa ctctttatta tataagatac aatagtctta
     1381 ctttatttat gtacacatgc ttttaggatg acaacatcaa cttaaatatt atgttacttt
     1441 ctaaatttaa gtaaatattg ccatcctaaa aattttacaa tttagcttca gatttaaaag
     1501 taaagtttaa aatattatat ttaaatctaa tttaatattt tttgttttgt aaatattatt
     1561 aaattaatat ttctaatata ttttccctgg atttaaaata tttttagggt caaaagctaa
     1621 ctttatattt ttaattaaca tcatataagc atctgaattt gattcatgta agtactcttt
     1681 tttagcatat cctatgccat gttcaccaga aacttgacca ctaagttctc tagatttttt
     1741 atacatatag tcaaaagttt cttttaatct tattttccat gtattatcat ccataccatc
     1801 ttttaaaata tatatgtgta gatttccatc tcctgcatga ccaaaacttt ttattcttat
     1861 ttttaatttg tcttgaagct cgtgagtgta tcttataaac tctgctatct tatctcttgg
     1921 aacaacgaca tcacattcat ccatttgtgt cgtagatgcc tttatagctt ctaaaaatgc
     1981 acctctggct gaccatatag aatcgtttct ttcttgtgta tctgatataa atacatctaa
     2041 tgcaccattt tctaaacata aattagctac tttttcatat tccttttcta tatcttcagt
     2101 gctatttcca tcaaatgtaa gtaaaagata agcatctgat gtattatctg gaaacttttt
     2161 acctaaaaat tcttctgctg ccaatattac atctctttcc ataaattcta tagccgttgg
     2221 tattgatttt gattttatta ttttaggaac agtttctatt gccattgata aatctggaaa
     2281 tggtataagc aaacttatac ttttctttgg taaaggaagc aattttaata tagctttagt
     2341 aactattcct aaagtacctt ctgaacctac taataaatcc tttatactat atccagaact
     2401 atttttaacc acctttccac ctacatttat aatttctcca tttggtagta caacttcaag
     2461 tcctcttaca taatcccttg taacgccata ttttactgct ctcataccac ctgcattagt
     2521 gtttatatta cctgcaattg tagcactttt ttcacctggg tcaggtgggt aaaataaatc
     2581 tctatcttga acatattgac ctattgtcat caataaaaca cctggttcta ctgtcaatgt
     2641 taaattttca taatcaactt caagtatttt attcatttta catagattaa tcattattcc
     2701 accatttatg gcaacagcag cacctacaag accagtacct tgacctcttg gtgtgactgg
     2761 tatattattt ttatatgcgt atttcattat tttagatact tgttcagttt caagtacatt
     2821 tactaaaact tcagggtact tctcaatccc tccaagttca tcatgtgaaa aatcttcatt
     2881 tatatcactt ccaactaata cattttcttc tccacaagta tctattaaaa aatctatatc
     2941 ttttttatcg attaatttat acatttctat ccccctattt agctgctgat gccatatatt
     3001 tttgattatt atctttgtta ttttctattt tttcaatcaa tttaggaata atatcataaa
     3061 tatcacctat taaagctaaa tgtgctacat caagtatagg cgctttatca tctttattta
     3121 ttgctactat atagtcagca ccctgcatcc ctgcaacaaa ttgaactgct ccagatacac
     3181 cacaagttat tatcaattta ggttttacag ttctaccact aagacctatt tgttttttag
     3241 catctatcca acctgcttct attacaggtc ttgttcctgc cacttgagcg tttagcttat
     3301 cagctaattt atatatcatc tccatatctt cttgtttttt tattgctctg cttgccacaa
     3361 ctatcacttc agcttcttcc agaccaactt ctttattttt ttcttttaca ctcagtacct
     3421 taattttaga ttttagttct tttttttcta ctttacataa agttatcttt cctgtagtat
     3481 tctctatttt ttctggtgct gaaaatattt tatatcttac agtggcaaat tgtggtctat
     3541 tattaggtgt gtttatatga gccattatat ttccaccaaa tgctggtctt atttggtcta
     3601 aatcagtatt tgattgaata tcaagtattg tacaatctgc tgtaagacct gttctaaatc
     3661 tagcggcaag tcttggagct aatgacctac ctaatgtagt tccaccaact aatactatcg
     3721 ttggttttat tttatctata aagttttcta ttgcttttga atatggttct atcctaaaat
     3781 ctttaaattc atcttcatca tatacaaata cttcatccac cccataagaa atcaaattac
     3841 tgcacttatc ttttatgtct tttcctacaa atacacaata cacaggttgt tttatttttg
     3901 atgccatctc acgagcttta cctataagct cgtacgttac aggatgtata tttccattat
     3961 gatgttcaac atatactgca attcccctcc attcatcttt attaatttgt actttactac
     4021 tctctataaa ttcaaatgcg ccttttggtc cacttttgac acacaacttg cacatcttac
     4081 agccagcact tatttctact atacctgact tttcttctat agccccaaaa ggacatattt
     4141 ctaaaattct ctttaagtca gttattttat cttgatttac aactatcttt gacatttatt
     4201 actccccctt acaccaactt taattcctct aatttattta caagtgcaaa acttagttca
     4261 tctgcatttc ctcttacaat atttttatct gtatttggct ttggaggaaa tattcttaca
     4321 acttgagtag gagaaccgtt aagtccatag ttattttcat ctttatcttc aaagtcatct
     4381 aagctatata caggtatttc tctatcttta gtattaagtt ttaatttaaa tgaaggtagt
     4441 cttggttgaa aaatgtcttt ttctacagtt attaaacatg gatattcaat ctcacatact
     4501 tgtaaatcat ttggcatatc tatttcaaca actatacttt catctttaac ttcaattaat
     4561 tttgtaacgt tagtaacatg aggtatatct aaaaattcag ctacttcagg tcccacctgt
     4621 gctgtatcac catcagtagt ttgttttcca caaattatta ggtctacctt tcccatcttc
     4681 ttaatacctt gtgatatggt ataggaagta gccaatacat ctgctcctcc aaatctccta
     4741 tcacttatta atgctccttc atcagctccc atcataaaac tttcttcaat taccttcttt
     4801 gcctgaggag gacccatgct aagtactttt agattcgctt tcttatcttc ctttattcta
     4861 agagctgttt ctaaagcata taggtcatag ggattcattt ttgaatctac tccatctctt
     4921 tttagtactc ctgtagtttc atcaacttct actgaagtcg ttccaggaac ttgtttaata
     4981 catgtcaaaa tttccataaa gtacactcct tttttattta actataactg atactccatc
     5041 aggtataact actactttgc tctccttacc aactatacta ttcgccattt ctaaagcttc
     5101 tttaaagtta aatgcatgtt tcatatgcat tttttttatc atttcaggat tacacttatc
     5161 tgttaccatt atcacagtat atttagataa tattctcgct agtatctgaa attcccattg
     5221 gtctggaatc gtatctactc tatcgacact tctaatttta tctaaaagtt gttttggaga
     5281 atctgcattt gctacatttt cataaaaaga ttgacctcca tgaccatcat tacatgctga
     5341 aatcattatt attactccac cgtctttaca agtagcttca gctgctgtca ttcctttaac
     5401 agattgataa atattttggt ctagtggata tccaccattt gtagttacaa caatatcaga
     5461 ttttatagaa tttacttttg ataactctgt tacaaatcta catcctttag tatgtgcttt
     5521 ttcgacatca ccagcaaagg aagcaattat ttttttatct ttatctatta caacattcaa
     5581 tatgaatgct aactttgcaa ctttagctgc atataccata tcctcatgaa taggattatt
     5641 attcaatttc ccagttcttg aattatcact atctataaag tcactacagt gattgtacat
     5701 tatagtcttt gcagatgcga ttcctggaag tacgcttttt ctgccacctg aaaaacctgc
     5761 aaagaaatga ggttctataa aaccttctgc tatcaaaagt tctgcctcat atgctagttt
     5821 gtttatatat aaatctccac ctgaaggcaa tatccctact ttacacatag atttatcatc
     5881 agtagatata tgcataacta tatcttcatt atctactatt tcttctccca ttttataaat
     5941 tagctcttcc cttgtacttg gcctatgaaa tccagttgcc actataatct tcacatcaat
     6001 ttctggatta acattcctaa tccttcttaa tataattggc atagttattc tacttggtac
     6061 aggtcttgta tggtcacttg taattatgac tacattcttt ttccccttaa ccagttcttc
     6121 cagagaatta gagcctatag gattattcat agattcttca actatctctt cttgagtctt
     6181 atgttctata taattatccg attttgactc caaaacaccg agaaaacgtt catcaggtat
     6241 ttctaaaatc attccttgtt ttgaatacgg tacttttaac tttaccattt ttaatctccc
     6301 attataataa actataaaat tggtatgtgg tcataccagt ttcacattta tatgatagta
     6361 ccattatcta ccatttgcaa gaataattta ttttataaca aacttttaat tttcattttt
     6421 tctataattt ttacttataa aatccatatg ttcctttgct ttctcacatg caagttctac
     6481 atcattttct acaactgcat tgtatatagc ttcatgctgt ttaagcaata tattttcatt
     6541 aaaaggttct gcgattattt tttctcttgc atcttctata aatccatcaa ataattttga
     6601 tgctgtcata aaaagacttt gaattaaata atttttactt aatgttgcta gtttactgtg
     6661 aaatttttgg tctaataaca ccagtactcg attattatct tttttattag tttctactct
     6721 catttcatct attatatgtt tcaattctat aacttcagaa gaagttattc tctttgaagc
     6781 aagttttgca atctcaattt ctaggattat tctaagctct aatatatctt caagtgtgcc
     6841 attattaagt ttaaaaatca tagataaagg ttctattaaa gttttttcta tatttgtaca
     6901 tataaaattt ccttcaccct gtctgctttc tatcactccc atagtctcta ataccctaat
     6961 agcttccctt atggaagttc tactcacatt catttgttca gacaattctc tttctgatag
     7021 taatttatcc ccctttttta actctccatt tagtatttta tattgtattt gctcaattac
     7081 ttgttcataa acttttttac tagctatact attaaacatt ttttcctcca atatgataat
     7141 cgttgttgta atatatatct attatatatc ttaaaccatt acattcatat atttttatta
     7201 cttttaatat aatatcttat aactcaaatt tacaggtgat attatgaaaa aaaataaaat
     7261 tattgctttt tttgctccag ctattatagt tggagttcta gttttaggga ttatcctata
     7321 cccaaatgaa gctataaaat ctgcaagaga aggcttctct atatggtcta atgttttagt
     7381 tccatcacta ctaccattta taattggagc aaacttaatt gttgatttaa aaatagtgga
     7441 tattataggg tttatcatca atcccataac tagatttgta tttaatgttt caggaaagag
     7501 cgctttagct tttgctatat ctacagtatc tggttatcca gtaggagtaa gtttagcttc
     7561 tgaatttagg agtaatgggc aaatttctaa gcatgaagca caaagacttg tgtctttttg
     7621 ttctacatca ggacctttat tcataatagg ttcggttggt acaggtatgt tccaaaattc
     7681 aaacttaggt tatttaatga ttctctgcca ttatctagga actatattgg ttggtctttt
     7741 ctttagaaat tatggtaatg aaaatcttcc aaagacaaaa ttggatttaa aaacaaatat
     7801 aaaaaatgta atcaacatta gaaattcaag tgggaatggt ttttttgttt tatttggaaa
     7861 tgctgtattt aatggagtaa atacattact tacagttggt ggatttgtaa ttgttttttc
     7921 agtagtattt aaaatactat ctctttttaa tgtaatctca ttaatagcat cagttatata
     7981 tttgcctctt tcatttttag gtgttagtaa agaactctgt caagcatttg taagtggtct
     8041 atttgaaatt actataggat gcaataaagt atctagtata acaagttctc cagaaatttt
     8101 aagagcatct ttagctagct ttttgatagg atttagtgga ttatccatcc tagctcaatg
     8161 ttgtacattt ctatcaaaaa cggacataga tttaaaatta tacatactaa gtaaatttgc
     8221 gcatggagtt ttagctgcta tctttatatt tatactttat ccaattgcaa actctgctgt
     8281 gttggtttct agctttgctg atacatacaa cgttatatat aataatttaa tctggtttta
     8341 ttatcttagc tattatgata caattcttca aattgtagta ataatttatc taatctcagc
     8401 agtatttatt gcaaaaaaac atatgaaaac tttatctaca aatgggaaac taatgcgata
     8461 taaaaatact ttttttatta agaaattttc acgaaaaaaa taaaactaat aaaacttaac
     8521 taaatacttc cattttttta ttatatttgt cataatttta ataacctttt taattagttt
     8581 aacagcatag ttatttcatc acaatttaat aattttatta gaaatatttt tcaaaaaatt
     8641 ctccttaatc acatatatca cacttgtata agtttactgg gaaatttttc cattatataa
     8701 tgtttcattt atattatata ataaataccg acctaaactt accaaatcaa actaagagga
     8761 gtggttgaaa atggcaacaa gacctataga aatagacgaa tataaaaaga taatggaact
     8821 attacatact ggctttactt atagtgaaaa tggcgttgaa aaaagattta gaaaaaatcc
     8881 taaagttgca ttggcactaa tgttagaagc taatttaggt ctaagaatat cagatatttt
     8941 aagattaaag ataggtaatt ttaaaggtaa tatgttggaa ataaatgaaa aaaagacggg
     9001 caaattacag tatagaccag ttaataaaaa tataattgag tccataaatg aacatgcaag
     9061 aaagtataat cttaaatcaa atgactactt agtaaatata aagacaaagg ctattcaaaa
     9121 acagttgagg ataatttgta aacacttaaa tctgtataat ataagtacac atagctttag
     9181 aaagctctat gctactactc aatttgaaaa gagtaacaat aatttagagt tggttaaaga
     9241 acttttaaat cacagttctg tagccactac acagcgatat ataagagtaa ctcagcaagc
     9301 tattaatgaa gctagtgaaa atttctttat tggttaatta taacgtatac atttttctat
     9361 tatcttatta attcaccaga tattaaaaaa gagtgtctca aaatgaactt tttagttcat
     9421 gagacactct ttttttataa aatcaaatat atttttatta tttcaatact ggaaaaaagg
     9481 cttgtctctc tattttgaga caccctatta aattttcata attcttgcat aaacatatta
     9541 atctatcttc aataattttt tagctgattc actgtaatta tttcttttta caatttccaa
     9601 aactctatca atctcatgtt ctgactttgc acttacaaaa atcgccaatt cttcatcatc
     9661 tataatatca taactatcta catatttatc taaacattct aaaattccat ctttattatt
     9721 atacccacca aatctaacta ctgcactaca ctcatcttct ataagtccac ttaaatccaa
     9781 tttccctttt gaaaaagact ttatatttga acttctatta tctattatat ctataatatc
     9841 tgcataaaca gcacttcctg ttgcacctct tccagctccc ttacctacaa aagaaagttc
     9901 acctactgaa tcacctacta aaataactac gttgaactca ttatctatct ttgaaagcat
     9961 attattattg tccactaatg ctggtctaac aaatccactt acttctcctg attcatactt
    10021 acttctagca accaatttta tcttacaatt taattttttt gcatattcta tatctttttc
    10081 atctattgaa gttattcctt ctaataataa atctttccaa tatactattt ttccataaga
    10141 taaagtagac aatatagata actttctagc actatcatat cctaaaacat ctgcatctgg
    10201 attaacttct gcaaatccca actcttgtgc ctgttttaaa gcaacatcat atggtaaatt
    10261 ttcatcatac atctttgata atataaaatt acaagtccca tttaaaatag cgtttatgct
    10321 ctttatattg ttgccttcca gtgattctat caatggtttt aaaactggaa taccacctgc
    10381 cacagatgct tcaaacttga tgctaacatt atttaagtta gctaattcta taaggtcact
    10441 acctttttca gccagtaaat ctttattagc tgtcactaca tgtatttttt tatttaacgc
    10501 tcttgttaca taatcaaaag ctggatttaa tcctccaatt acttcaacta gtatatcaat
    10561 atccttgtca aatatatctt ctatatcagt agttatctta tcaaaatact tcttatactt
    10621 gtgtttttct ttatttttaa ctaaaattcc aacaacttct atatctcttt ttgaagtatt
    10681 attttctatt aaatcaatta atccacttcc tactgttcca taccctaata ttgctatctt
    10741 cactgtaaca tacccccatc attttgatta tattaaatta tttatatata taaatatacc
    10801 aataaaaaaa gcttgagtat aaactcaagc catatgacgg gtttatactc atctttcagc
    10861 ataaatgctg caggatttag caccaatgta taattaaata tactggttgc cgggcttcac
    10921 agggccagtc cctctgccac tcttgataag attgctaatt aaaatttatg tttaatagta
    10981 taatacaatt tcttccaatt gtcactattt ttttaactta tttccctaaa aggatataaa
    11041 ctattatcta acagctcttt tagttggttt accctttttt gtaacattat tatttttagt
    11101 ctttgctttc gcctgttcat gtcctggaaa aagtatttta ggctcttcaa tattcctctt
    11161 gtaaatagta aatttaaaac caatagcctg cacaaattca gctcttaaag cttcacatac
    11221 tgcattagca gtttctttag tatcaagacc tgcattttct aatatagtaa cttttactaa
    11281 ttctctagtt cttaacatac catctaattg ctctaagaaa ctctctgtaa caccttcttt
    11341 accaatttgt gtagtaggct ttaaagtatt tgctaaagat cttaaatacg ccctttgttt
    11401 tccttttaac atattctcac ctctataatt ctatacttaa attatctata atctatattt
    11461 aaattaattg taaaactcaa attctaattc ataaatttta accacatctc catcttctat
    11521 tcccatttct ctaagcctat caaaaacacc ttgactctcc atagcttttt ggaaatattg
    11581 aagggattcc atatcatcaa aatttacaga atacattatt cttctaagtg ctttacctgt
    11641 aactacatac acaccatctt caatatctat acttaactct tcttcagtac caatatcaag
    11701 ttctggtcta tacatttctt cttctgaaac tagctccaca tcttctactt cttttagcat
    11761 tttagaaaca taggctatta cttcatctat gccttgacga gttgctgctg acattttaaa
    11821 tactgtatat cctctgcctt ctaattcact cttaaacttc tcaaacttac tctcatcttc
    11881 taatatatca aatttatttg caactacaac ttgtggcctc tttgaaagct tttcattgta
    11941 caatttaagc tcatcattta tcttgtcaaa atcttcaata gggtctcttc cctctaatcc
    12001 agatatatct acaatatgta tcaatacctt tgttctctca acatgtctta agaactcatg
    12061 acctaatcct atgccttcag aagcaccctc tataattcca ggtatatctg caagtacaaa
    12121 actatctcca aacttagttt gaacaacacc tagatttggt gtaagtgttg taaaatgata
    12181 gtttgcaatt ttgggtttag ctttagttac aactgataga aatgttgatt tacctacatt
    12241 tggaaatcct aaaagaccaa catctgctat cattttaagt tcaagagtta tccatctttc
    12301 ttctccatct gtaccagatt ttgcaaaagc tggagcttgt cttactgcat ttgcaaagtg
    12361 ttggttacct ttaccaccta taccaccttt tgcaactata gctgtatctc cttctttttt
    12421 taaatctgct aatacaagac ctgtagcctc atctcttatt actgtacctg ctggtacttt
    12481 taatactaaa ttttctccat ttttaccagc tctttttcct ttgcttccgt cgccaccatt
    12541 ttgagcttga tattttttct ggtacttaaa gtccattaga gttctaagcc ccaaatcaac
    12601 ttcaaatatg atgcttgctc cacgaccacc atctccaccg tctggaccac cagctggaac
    12661 gtatttttct cttctaaatg ctaccgaacc atttccacca tttccagcct taacaaatat
    12721 tcttgcctta tctataaaca aattcttcac ctacttaatt aaaaactttt aattagcatt
    12781 accaaaaata ccattataaa ttcatcagta ttataagaaa aaggagtgcc tcaacactcc
    12841 ttttatgtat attactcagc tattgctact ggatatatac taactttttt tctcttcttg
    12901 tcttttcttt cgaatttaac agtaccatca actaatgcaa ataaagtatc atcactacct
    12961 tttccaacat tagttcctgg atgtatttta gttcctcttt gtctaactat tatacttcca
    13021 gcagttacta attgaccatc gaatctctta acacctaatc ttttagatat agaatctcta
    13081 ccatttttag aagaacctac ccctttttta gatgctaata attgtaaatt catgtttaac
    13141 atatggagtc accccctact tttttaaaat ttttatattt tttgggtatt cccgtttaat
    13201 ttctttaacc gctaattgaa agtgatttag taataattgt gcgtctttta catgcgtatc
    13261 tttgactata cactctatat gaccttcttc tcctactact ttttcaaatt caatcttttg
    13321 taatttgtct aaagaattta taactgcaat agcattagat gtaactgcag cacatactat
    13381 atcatagcct atttcagcaa aatcagcatg tccctttaaa caaaaacctt gcaacaagaa
    13441 atcatcatta taataatatt taacttttat cataacttaa ccaataacta agcgtttatt
    13501 ttttctacaa ctatcttagt gtatgattga cgatgtcctt gttttcttct gtaatctttt
    13561 tttgctttat acttgaaaac tataactttc ttagctttac cttgttcaac aactttagct
    13621 tgaacagatg ctccttctac tactggagaa cctaatttta attctccatc tttagagcaa
    13681 gctaatactt cgtttaaagt aacaacatca cctgcgttag cttctaattt ttcaacgaat
    13741 aatacatcac cttcagaaac tttatattgc tttccaccag tctttactat agcgtacatt
    13801 aaatacacct cctcggcctc aaactcgcca gtacaaggta cttcatttga agatttaaac
    13861 ctttactgtg cggcattaca attattaatt ataaaatatt tacattttat tgtcaactat
    13921 tttatcgaaa ataacattgg ttttattgtg ctttaatgta ctatttgcgt ttaaagaaat
    13981 ctttatatta tatttttcac caattttatc aattatatcc atataatatt cttttatttg
    14041 ttcaaaaata aaatcattaa attctaccat tatgtttttg taaacagtat gttcacttat
    14101 tctcataatt tctttttcaa tactatctag tatataatgt acagatttta ttgtttgttc
    14161 accatcacaa catggacaag acattaaata atacttatca atggattctt tttctctacg
    14221 cctagcaact tctactaaac caagttttgt catacctaat acttcagctt ttcttttatc
    14281 tttattaaat tcttcttcta ggatgtgtaa aatctccttt tgatgcttct ttttatgcat
    14341 atcaataaaa tcgattatta ttatcccagc tatgtctcta attataagct gtcttacaat
    14401 ttcttttgca gcttcaagat tagttttata aacggtttca tcaagtttac cagttccaat
    14461 aaacttaccc gtatttacat ctataaccgt aagagcttct gttttttcaa ttattaaata
    14521 acctccactc tttaaccata cttttttatt taataatttt tctattttag attctattct
    14581 gtataaatca aatacatctc tattttcctc aagacacagt ttatcaacat aagtcttatc
    14641 tatacctctt aaaatagact taagttcaga gtacttatca taactattgg taattataga
    14701 ttcaatatca tcattcacat tatcttttac atatttagtt gcaaaatcta aagacttata
    14761 taataatttc ggacctatac caagtttata ttcttttaaa atattttcat actttaattt
    14821 caactcttct atatctttct ttatttcatc atgagtgcaa ccttgagcct cagtccttat
    14881 tattaatcct agattttcct tatttactgc cttagtaatt ttttttaatc taaatcgttc
    14941 tttttcatca gtaattttat ttgatattgt agttctatca ttggaaggta tatagacaat
    15001 ataccttcca gaaatactaa tctcagtgtt taattttgcg cctttagttc ctatttcttc
    15061 tttatttatc tgaaccaaaa tatcctgacc agattttata gtacttccct tttttaattg
    15121 taaataagca agtttcttaa atccaatatc tacaaaacaa gcttctattc ctggtataac
    15181 tttttttacg attccacgat atatattgga tacagtcttc ttatttaaat tgtcttcaac
    15241 aaaaagttct gttaatcttt catcttcaag tactgctgtt ttctgggacc ctattaggga
    15301 ctcaataact atctttttca caacttcacc tctcgagctt acataggagt cactaattcc
    15361 ccatcttcta atacatataa atctcttctc aatatatcaa catctaatgg gtcaatatca
    15421 agttcaaaca tctctaatat ctttggtata agtatattag tatttaaatt agtttttgag
    15481 cctgtagcta tagtagcagt aagagtaata tgttcatctt ctaaatttaa aacatcaaag
    15541 gttcttatca taggtcttat atctacttca accatcttac cttttttatt cttttttgtt
    15601 atgattattt ctttattatt cataaagtca attacttttc tttttacaaa ctctttcgtc
    15661 ataggtcttt tcaaatctat attaaacaaa tattctccat agtctatcac agaagaaaga
    15721 gaaggtgttt gtctatcaat ttcttttgct ttgataaaat ctatcccatc tggaagttga
    15781 attgatactt tatttaaaaa ttcctctact gataaatcat cttcttctat ttcaatatct
    15841 acatactcac cttgactttc tgtccctaaa gccaaagcat tgccataact cattttaggg
    15901 tgaggattaa atccttgaga atgtgataag tttatttcag ctcttctaaa cgctctttgt
    15961 aacaatctct gaaggtcaag atgtgatata tatatcatgt cgccttcctt tttaaatttt
    16021 actcttatta tcttactcat attagcaaag cccccttcct atatcatgta tatttattcc
    16081 acaaccattg cagttatgtc tacaatcaga agtgattttt tcttttttag cattttcgtc
    16141 ttctctaatt aagaattttt tactaatacc tacatctata tggtcccaag gaaatacctc
    16201 ttcatagttt ctatttctat gtgcataaaa atctatagaa agattattct tttccatagc
    16261 ttctttccat atatctaaat taaaatgttc tgcccatcca tcaaatttag cacctagtct
    16321 aaatgcatca tatataactt ttcctattct tctatcgcct ctagctacta ctgcttccat
    16381 caaactagtc tttgaatcat gataattgta ttttatattg ttatttctta atttatttac
    16441 taaatgtctc tgcttattaa taacttcttc tgtagtatct tgaccatgcc attggaaagg
    16501 tgtaaatggc tttggtacaa atgtagaagt actcactgta acactaaaac ttctctttag
    16561 ctttcctcca tttacttttc tataaatatc aataacttta taagctaatt tagctatacc
    16621 atctaaatct tcataagtct cagttggtaa accaatcata aaatacaact taacactatt
    16681 ccaccccatc tcaaaagctc tttctgttgc attttccaaa tcttcttctg taacaccttt
    16741 atttataaca tctctaagtc tttgagttcc tgcttctgga gcaaaagtaa gtccagattt
    16801 tcttacttgt tgtattttat cagcaatttc cattgaaaaa ttatctaatc taagggatgg
    16861 aagcgaaatc ccaatattat tagatgcata ttcatctacc aaataatcag tcaactctga
    16921 taacttacta taatcactcg tactaagtga tgataatgat atttcatcat atccagtatt
    16981 cttaactaat ttatctaata tttctttaag tcttttaaca ctcttttctc ttattggcct
    17041 gtatatcata cctgcttgac agaatctaca tcctctagta catcctctaa ataattctag
    17101 tactattcta tcatgaacag tatctatata aggtactatt agtttttctg gataatctac
    17161 agtctcaaca tcttttatta tccttttagt aggattttta gtaatccctt ctctattagg
    17221 agttacactt tgaactgtac catcttcatt gtacttgaca tcataaaaac ttggtatgta
    17281 tactccttct atgctagata ttttatataa aaaatcttct ctagtcgttt tatttttctt
    17341 ccattcttta tactcattta ctacttctaa attaacctct tcaccttcac ctaatattac
    17401 tacatctata aaatctgcta atggttcgga attataagca caaggaccac caaccattat
    17461 aaatgggtct tccaaagttc tttcttcttt taatattggt atattggcta aatctaatat
    17521 atttaagata ttagtgtatg aaagttcata ttgaagtgta aaagtgacaa aatcaaagtt
    17581 tgttataggc tctcttgact ctaatgcaaa taatggtata cttttttctc tcattatatt
    17641 ttccatatca actgcaggag aatacactct ctcacaaaat acatcttcat ccttatttat
    17701 tacatcatat aatatatgac tccctaagtg actcatacca acttcatata aatctggaaa
    17761 gcaatgtgca tatcttatca attcactatt actagtatct ttatgaattg aatttatttc
    17821 atttccaaga tatctagcag gcttttctac tttttttaag atttttttca agtctacttt
    17881 attcatttat taaaattcct ccaaacaagc tctttatttt tattcttatt tataagtagt
    17941 attatacacg ataaaatatt ttctatcaaa aatataacta aaatattgaa tttaaaatac
    18001 atattattca caaaatagaa tagctaaaaa tatttaagaa tattttctat taaattttta
    18061 ttgaaataca atttttttac aaagtatgat atattataaa cataaaacta ttgttttaca
    18121 tgacttatca tgacatcttt tgtttcattc acctcaaaat tgggtatgtt acttatataa
    18181 tgataaattt taggagggtt aaaaatgagt aaagtttttg aagtaaaaaa agatatctac
    18241 tttactggcg tagtagatga aggtttaaaa gtattcgaca taataatgga aactgagttt
    18301 gggacaactt acaactctta tttaatcaag gacgaaaaaa cggttttatt tgacactgta
    18361 aaggcaaatt ttaaagatga gtttttaagt aatttatcag aggttactga tatagctaaa
    18421 attgactatg ttgtaattca tcacacagaa ccagaccatg caggtagttt aaaatactta
    18481 ttagatataa atcctaatat agaagtttat tgtactaaag ctgctaaact atacttagat
    18541 ggtcaaataa atagaccttt taactgtcat gtaataaaag atggtgaaat tttaaatatc
    18601 ggtaaaagaa atcttagatt tataactgct ccattcttac attgggttga tacaatgttt
    18661 acttacattg aggaggacaa gactctttta acttgtgatg catttggttg tcactttgca
    18721 agtgttgatg cagaggtagt gaatagtgaa gattatctaa aatcagctaa acactactat
    18781 gattgtatag ttaagccatt tgctaaacat gttttaagtg ctgtagataa ggtggtagga
    18841 ctaaacatag aatttgatac tatattgact tctcatggtc caatgcttac taaagaccca
    18901 atggctgctg ttaaaagata tgttgagtgg tctacagaag ctgttaatac aactaatcaa
    18961 aatcaagttt ctatattcta cttatcagct tatagtaata ctttagagat ggctaaaaag
    19021 ataaaagaag gacttgataa agaaggtgca aaggctgaat tatatgattt agaagatatg
    19081 acattaacag aaatgcacga tacattagta gtgtcaaaag taatattact aggttctcca
    19141 actataaaca aaactatggt taaacctatg tgggatttat tctctgttat agacccaatg
    19201 gctaaccaag gcaagatagc aggagtattt ggttcatttg gttggagtgg tgaaggtata
    19261 actatggctg agactttact taaatctatg tcattcaaaa tgcctgtaga atctcttaag
    19321 aaaaaattct tccctagtga agagacatta aaagagtgta tggcatttgg tgcagaattt
    19381 gcaaaattag ttaaatagcc attaatcaca cataatatta tttaaaataa atgattttat
    19441 atttaaaaat aaattaaaat ggagttgtct caaaattaat ttttctaatc taattttaag
    19501 ttcaactcct tttttatttc ccaaaatgac taatataatg ataaatgcac cctcaccaag
    19561 agggtacatt atttataatc ttttctattt gtatacttgt atatttatat taattcacat
    19621 atctagcata tcttacttgc cctcttccag aattaggttc tatttcacca atttctattt
    19681 taataattac attattgttt ttacactttt ttgataattc tgctgcagaa aggtttttac
    19741 cagtaaaatc taaagaaaat ggcttatcat attcaaaagg atactcaaca ggtacaccat
    19801 ctggagctaa tgcaaccata ccatatggtg tattcataaa ccctattaca gaaactgtat
    19861 gccttgatgg gtctaaattt gaatttttgc ttgtaaactt aattgtattt attgatgagt
    19921 tgattaaact acacggaact ccctcatacc tttcaatttt gggacgtaga ttatttccat
    19981 aaacttcatc aagtattgct tcttcttgat ctgctatcat agtgtgattc ccaggtccaa
    20041 ctggcgcaga aggcttagct ggcgtaggtt tcttaacagt tggcgttgga ttctgtgtct
    20101 ttactgattc accaacagct ggataggctt tcttgtcaaa tggtaatggg tgagtaagac
    20161 tcttgtatat gatgtctgct cctgctgatt tgttggcatc aatatctaca tgatacaaac
    20221 gtccatcctc aaaacgaata agattccact gatggtcatt tgttgtacta tgtacataat
    20281 aacattcaat tcccatagca tcacataaag ctttcaagct cctacacatt ccagaacaag
    20341 cacctttttt agtaaccaat gtataagcag tattggctcc ctctgctgcg ttccagttaa
    20401 catatgttgt gttgttttta atgtgattat aagcaaccct aatcttagca tctgtggtca
    20461 tgttctttgt aattttcttg ttcataaagt ctgctgttgc ttgtgctacc gaattaagtt
    20521 gagcttgtga taactttgga ccatatatac tgttggttcc agctacatag cttttcggtg
    20581 tctttgcagt aacatcttta gctgtcatac cataaactgt tacactcata catgaggtta
    20641 aaaccatcgt tgcaatcaat agtttagtag ctaatttcct gatttttttc atattagcat
    20701 tctcctttat aatatatttt actttcaatt ccctaccatt aattaagttc attttagatt
    20761 taaaatatgg attatcaaca tgtgtgcata gcaattcacg tggtcataga atatttagat
    20821 ttcttggaaa atctgttcta tatttcctat atagttcgta cacaatccaa ctcacaaacc
    20881 tgcatttttg atatcatcac aataaaatga taataattaa tatattcaaa aatgttggtc
    20941 tgtaacaggt ttgtcaattt tctaattatt ggtaatgacg agagtgagga gaattgtcaa
    21001 taatacattt aaaattaaaa ttgtatacac ttcatacatt ctcccctaac aacattatac
    21061 agattataat ttgtatattc aatacatttt ttggaaggta taattatatc aaaatatgtg
    21121 attatgtata gatacaatcc actatggaga aatataaaag aaaagagtat aacaaacaat
    21181 aaaaaataag atgattcaaa ttttattttg aaacatctta tttactctac aaattaaaat
    21241 tatttggtga attatttaat tattattttt tattaaagaa attttaaatc ttaatataaa
    21301 atacgctatt atacataata atccaaatgc aaatgctact ggaattaaca tctccgattc
    21361 aaaataaaag aaatattcta agaaaatatc tggatttact atattcccat tcttgtctaa
    21421 aaaatctttt ccattatatc ctaaatgctg tataaaatta cttatgttat tataatctgc
    21481 ttccctctca tataccatat tagcattcaa tccagaagaa cttaaattag tgtttccatc
    21541 tttcatatct attacatata gtctaagagc tttgacttta ctatacttat ctttatcaag
    21601 tattttttca agttctaact tatattcacc aatatttgtc atatcatgtc tttctgccaa
    21661 ttgctttatt tctccatcaa gttcttttcc taaattatac atattatgtt gtaaactatt
    21721 attgtaatac cacataaatc cagaaattaa aaatgcaatt atacttatgt aacctaatac
    21781 ttttttaaac cccattacaa ttgatttatg cctatccaat gataaagata gttcttttat
    21841 tatattacat aattcatact gcatttcatc accatcatca aatctttcaa ttgctttttt
    21901 acatgcttct tcttcatcta atccttctaa tttaaattca tttgcagatt ctataagatg
    21961 gcatctcatt tcctgtttta attctatagt acttttattg tcacattttt tatatagttt
    22021 atctaaatat tcatctatta gtttcataaa ttaatccacc tctcccaaaa attgattcat
    22081 aaccttttta ataaatctcc attcttgttt ctttatttct aaaaaatctt taccttcatt
    22141 agttaaatta taatattttc ttcttccacc tgaactttgt tcattgctat aataagattt
    22201 aattaaattt ttagattcca ttcttttaag tgcaagatac attgttcctt cttttaattc
    22261 aaactcactt ctttctctta cttgctttgc aatttcatat ccataacaat ctttcttttc
    22321 taatatagaa acaattaata tatcgatata accttttaac acttctttat ttaactgcat
    22381 tatgtaccac cgccttttca cctactactc tataatgtat agtacttata tttactataa
    22441 taatacatag tactctataa tacaaggttt atattctaca atagacttaa aaataataaa
    22501 tagctgtata ttagtattta tagattaaat actaatatac agctatttat caaattttaa
    22561 aaataaattt ttgttttatt aatgttgtcg taacaacatt tacttggttg aaatagtatt
    22621 acctataagt ttaaatatat ataataatag acttaattct atttcatatt attaaaatag
    22681 agtaatagtt taaattctac tactctatct ataatctatt tcctaattat ttaatctcaa
    22741 atttagctcc tcatcattta aatctttcat aagatttcta caggtactag gtttattgca
    22801 acagaaaaac tagggcatta aacacttata tatctgtttc tttagactgt aatattaata
    22861 ttttttaaat acgttgactt ttgctttttc taacttctct ccatgatagt tctcctctat
    22921 caagagcttt tataaatatt tctgctgaag ctagatttgt agctattgga acatgataaa
    22981 catcacaaag tcttattaac gcttgtatat ctgtttcatg agcctgagat gtcaatgggt
    23041 ctcttaaaaa aataactaaa tctatttctt gtgttactat taaagaacct atttgttggt
    23101 ctccacctaa aggaccagat gctaatctat ttatatttaa ttcagtttca tccattattc
    23161 tttttcctgt agttccagtt gcatatagtc catacttttt taaaattgat tcataaccta
    23221 tacaaaatcc gaccatagtg tttttcattt ggtcatgtgc tactaatgct atattcatat
    23281 atctaatctc ctcaatttat gtttagatgt atttaaattt agaaatttat tttctttctt
    23341 ctcatacaca catttagtac taatcctaag tttgctaaag atgtcaataa cgaacttcct
    23401 ccataactta caaaaggtaa tgttactcca gttactggta ttaacgcaac cgtcatacct
    23461 atattttgga ttatctggta accaaacatt cccataacac caaccactat gagggttcca
    23521 taaaaatctt ttgcatctct tgcaattgct aaaagcctta ataggaatat cataaataag
    23581 attatcaaca ctgccattcc tattacacca agttcttcac ctacaacagc aaatataaaa
    23641 tcactatctt gtacaggtaa aaaatcttct tgattttgac ttccattgta aagtccttta
    23701 ccagttacgc ccccagaacc aattgcaatc agagattgca taacttgata gtttcctttt
    23761 agagttacat cttctggatt tagaaaagct tctattctta ccttttgatg gtctgccatc
    23821 attaaataca tcagtggcat tgacactaat agtatgatta ttcctctttt tatcaacttt
    23881 gagctaagac ctgctgtgaa cagcattgca aatatcatac aacaaaatac aattcctgtt
    23941 cccaagtctg gttgtgcaat caataatccg ataaatggaa gagaataaac tacaacaggc
    24001 ataacttcct ttaacgtatt taatttatcc tttttggatt caagtatctt tgcataactt
    24061 agtacaaatg ttaatttgac tatttcagat gtctgcaagt caagtggtcc taagttaatc
    24121 cacgacctag ctccaccttt tactgtccca attccaggta ataaaactat ggctaacaaa
    24181 ataagactta ttatataaag cgctttataa tacctgccta gaagattata gtcaaaaaat
    24241 aatatgacta taatcattcc tataccaagt acaaaagcta atccttgttt aatcaattga
    24301 ttatatgaac ctgttgaatt agcatgtgtt gcactactaa gtataacaag cccaaaaata
    24361 aagatagcta atactgtaac tataagtttc cagtctaact gttttatcaa cttaattgtc
    24421 gacttataat taatattgat ttttttcaaa gaatcaccgt ctttctatct ttaaacatat
    24481 aattaaataa aaggggcata taccaataag gatatccccc ttttaagcac taattacata
    24541 catctatctt ttatattctt tagtggtata ttagcaacta atgcagatac aggtttgtca
    24601 tcatgctcac ctctgcattt agacattttt atttcaagac catcatcttc tatttctgca
    24661 taattagcta ttacttttaa aatgtctgtt tttatcatct ctaaaagttg tggtgaacaa
    24721 tctactctat catgaactaa aactagcttt aacctctctt tagcaacaga tttactagtt
    24781 ttagcctcgt tagaaaaaac tctaaataaa tctaacacag atgtatcctc ctttgctact
    24841 tagccatgct aaacattttt ttaagtctac caaagaatcc atcttcaact tcaagatcaa
    24901 gtagaggaac ttcttcattt agtatccttt ttgcgatatt tttgtatgct tgaccagcaa
    24961 gtgacttaga atcaagtata gctggctctc ctttatttgt tgatataatt atgctttcat
    25021 catcaggaac aagacctaac aaatctattg ctaatatttc tattatatct tgtttatcca
    25081 tcatgtctcc acgcttaacc atatcatttc taattctatt tataactaat cttatctctt
    25141 ttatttcatt tgcttctaat agacctatta ttctatcagc atctcttact gctgatattt
    25201 ctggattagt aactacaata gctctatctg ccccagctac tgcattttta aagccttgct
    25261 caatacctgc tggacagtct attattatat actcgaaaga ttcttttagt ttctcacaca
    25321 gatcaatcat ctgctcaact gagacagcat ttttatctct agtttgtgct gctggtaata
    25381 aatatagatt atcaaatctt ttgtctttta ttagagcttg cttaagccta caagttcctt
    25441 caactacatc tactatgtca taaactattc gattttcaag acccattact acatctaagt
    25501 ttctaagtcc aatatctgca tccacaacta ctgttttttt attttctagg cttagcgcag
    25561 ttcctaagtt tgctgcggta gtagtttttc caaccccacc tttaccagat gttataacta
    25621 taacttcgct cataatacta ccccctattt ttctttctat ttgtctaact ttgacaaata
    25681 gctttcgatt acaattcttc cattacttac aaaggctatt tctgggctaa tttctgattc
    25741 attttcataa ttttcttcat catctggagc ttctgcaata ttatctgcta tttgtaatat
    25801 tttaggatta agatttccag caacaacata tgcaaattca ttgccttctg cacctgcatg
    25861 tacaaaacct tctattttac ccattacaaa aacattacct cctgctacaa ccttagcacc
    25921 agcatttata tctcccataa caactgtatt tgattttgaa aggacttttg aaccaggttt
    25981 catatcattc aatataacta catcaccttc aaattcaata ttttcaccag atcttagggt
    26041 attgacatat tttgttggaa aattactatt ttcttcaatt ttttgatctt caacaaattc
    26101 cacatcaaat ctagaagtaa ttccttcttt aagttctaga atctccatgt cagttaaaca
    26161 atcactatta attttactaa ttttagcccc attaaaaaag ccaacatatg cttccaattt
    26221 gtttattatt ttttcctgta tttcctcaaa tggagcttct ctttttatat ttactattat
    26281 ccctctttta ttacccttga actctactag ttcttgacta caaatttctc ttaaagacat
    26341 aacaacctcc agagtgatat atcatttata ttcttcaaat acgctttaaa cccttttatt
    26401 ttttctatat aaagctaaag tttatacata gattaagcta tctattaatt tgtgactcga
    26461 aatttatatt ttcgtcagaa gaattgttaa catcattcgt cttgttgtca tttttactat
    26521 tagttggctc taatcccata taagttccaa taacttctct agttggtaaa agtgagaata
    26581 cacttgaatc accttgagga attacacata caacagctat ttctgggtca tctgctggag
    26641 caaaagcaac agtccatgta aaagaaccat aatcttgttt aaatctatct atttggtcat
    26701 ctgttatttt tggatttaat tcttttatag cttttcttag atatgaagaa ttcaccttat
    26761 cagtgtcctc taatctaact tttactccat cttctaattc ttcctctaat ttctttcttt
    26821 cttcgtcttt caaatcttta ttttctaatt tcttttttat ttccttttcc ttagctaatg
    26881 aaagctcttt ttctttttct gctttcatct tatcagctag tttaatcgca tcatttaggt
    26941 tgacattata agatgacata tgacttttta aatattcata ctcgttatct gtaggtattt
    27001 tcccactttt ctcagctgta ccagtttttg ctgctacatc tattggaaaa tcagcaaaag
    27061 cactcttcgc tgtaccttgt cttgcaacca atttcatacc ttttgttaat tcttttaagt
    27121 tatctggatt tttaaaaggt attttttcga ctttcttctg gtcattaatt ttaactgatg
    27181 aataatcact tgaaacagct ctatcaacta cagataattc tactaaatta cctccatttg
    27241 ctatagcagc tacatatctt gatatttgag ctggtgtata agcattttca ccttgaccta
    27301 tagctaagtt aaatgtatct gcagtactcc attttgcaaa gttaaaataa ctgaatactg
    27361 ctaaatctgc tacttcttct attctatctt ctttaacatt cattttcttt agcctattca
    27421 ttgtttcgac tctaccagga gttttctttt ctgctgccca gcttacaatc tcattgattc
    27481 ttttctcata ttctttagga tttttttctc tagttatatc aacaaaatca tttgccattt
    27541 ctctttctaa atttgacttt agaagagctt gtgttgattt caatttatct tctgtgctag
    27601 gaactttacc tgctctttct tctacttcat cttgaagccc tgtattttgg tcaagcccaa
    27661 ataattttgc atactcaagt attttatttg cattcatatc tataccaatg ctttttccat
    27721 ctggccatgt tttacctgta ccaattgttg ccatatatat attacaagac tcttgtatcg
    27781 ctttatataa gtttgtcata ccatggtttc ctctaccatg gttccataca tagtcaccaa
    27841 aagatttttt acctaacatt ataaccccag ggtcatttat agtaaagttt ggatccaaac
    27901 cattttctaa tgctgccatt gaagttagca tcttaaatga agaacctggc tgaaattccc
    27961 cttgtgtaac caagtttaaa agtggacttc ctgctagtaa gtcatttgga ttttttggtt
    28021 gaagtgcttt ataatcctct gtagaaatac cttttgcaaa tttatttggg tcataattag
    28081 gataacttga tgaagctaat acttctccat ttttaacatc aatagctata agagctgctg
    28141 actgtgcttt tcctgcatat gcactaattg gtttgtcccc aaatttactt ttaaaagtac
    28201 ctcctttaga agcaacttcg attatctgtt ttaatgcatt atctgaaact tcttgtaaat
    28261 ctttatctag tgtaagatac acagtatctc ctgatttagg ttttttagat tcaatttctt
    28321 tactgattct acccaatgca tcaactttaa ccattttata accatcagtt cctcttaatc
    28381 tactttcatt actcttttct actcctgcaa gacctaccat atctccagtt tcataacctt
    28441 tttgaaggta tgattctatt tgagtggatg gcatttttcc tacatatcct aacatatgag
    28501 aagctaatga cccattagga taatatctta ctggttctac tgctattgaa acaccaacaa
    28561 ggtccatagc actttcttca atttgagcaa tcgtagtttc tcctacatcc ttagcaatag
    28621 ttactggatt atattgagaa tatccttttg attttatcaa atcccttacg accattattt
    28681 ttcttgcatc ttcatcactc aaacttttat caatttctaa tgcatcacta tttcttactt
    28741 tttcaaacgc ttctttggca ctcagtttag tttcttttat cttataacta gccaaccaat
    28801 ctctcttatc tctttctgct gtgaacatcc atttactaac taaaataggt ggataatatc
    28861 cattttcatt tagttttgcc tgtaatcttg tcgcatccaa tcttttatct tcttgagata
    28921 atattccagc tgatataagt ttgtctacta agtaataaaa actttcctta gcattataat
    28981 catttggaat accattttct gatttatatt ccctaatatc tctgtcatat gtataatagt
    29041 actttccatt ttctacatat ataggaaact catctacata ttcttcacca tttctctcca
    29101 gcaaatttat aagttttaat gatatttcat ttgctcttga atgcttattt gcatctttct
    29161 tattaatatc gttacctgaa acttgaacag taaataagtt tttatttcct gccaacagtc
    29221 ttccatatct atcttttatt tctcctcttg gagcttctat tgccaacttt ttatatgttt
    29281 tattctcagc taactcattg taatattcat atttaaatgt agtcatatag attattttta
    29341 ctaaaatagc taaaaatatc acgctcatga ctatcttaat tatttttagt ctatcaactt
    29401 gtttattttc ttccatgaaa tcaccaacta atcttcttta agttttaaaa ctgctctttt
    29461 agataagcga tatattacta aaccaattaa actattcact attggtgcta ctagtagacc
    29521 ttttacaaaa agtgttgata tgttgtagct ttgataaatt atactagatg tacctatatt
    29581 gacaattgaa tcaattaaac tgcctataaa aattaaaacg aaagtaataa tataactacc
    29641 tttatatagc tgatctctca tgtatccaat tgcatatgca ataataaaca aaattaatgc
    29701 atttacacca aaaattccac caacggttat gtctttaata agccctatta ttgctgctat
    29761 aatcccacct tctaattcat ctaaataaag agagattatg gttacatata taagaactaa
    29821 attaaagctt atgccaaaaa tatctatata atttgttata ctattttcta tagtcataag
    29881 cacaatcccc aacagacaaa gtaaaacttt tttcattgtt tttatcccct ttatcctata
    29941 tttcttggtt ctatgactac aacgtcattt atattcttaa aatcaacata aggttttaca
    30001 actacatatt ttaatgactt atctttatca tcaaccacct tttcaacttc gccaattggt
    30061 ataccatctg ggaagaatcc aagacctgat gttgttatta tatctccttg aattacatta
    30121 tatgatgagt caaacatata tccttgcaaa tatcctttac tattataact atctttatta
    30181 tctaaagtag tattttgagt aattgtacct ttagcattgg catcctttgc tagtttaaag
    30241 cttacagatg ccttagaatc caatagtgaa attgccttac tataattgtt ggaaacttca
    30301 taaactatgc caactaaccc actaccattc ataactatac tttctttttt tacacctgaa
    30361 ttttttcctg cacctatgac aaaactctca taccagtttc catcattttt accaacaaca
    30421 cttgctgaaa tacttgtcgc cttatactct tcttgtacaa agttcagtgt cttttttaac
    30481 tcttctagcg attctgtttt atctagtttg gcatttaaag ctatcatatc ttttttaagt
    30541 ttttcatttt cttcttccaa tttttttacc tttttagaat tatctttaaa atttgctaca
    30601 tctttaaaac catttttgat aaaagaaaat ccatcattta ttcccttacc tacacttgta
    30661 atagcatctg aagctactcc taaatttact ggactaccac tagaaaattt accaattgat
    30721 atacccacaa ttccaattaa agtgatagca actacgcccg ttgctatcac tttaacatta
    30781 atcctttttt tctcattttt gttcttgtca aatctcaagg ccatcaccaa cttctaattc
    30841 ttagtattca tcattaatac tttttcaaag atttcttggt cttcaacaga tttacctgtt
    30901 ccaagtgcaa cacaatcaag aggtgtttct gctatttgta cagacatacc agtttcctgt
    30961 gtaataagct tatcaagacc tctaagcaaa gcgcctcctc ctgttagcat tattccgttt
    31021 tccattatat ctgaggctaa ttctggtgga gttctttcta gtgtagattt tattgcatct
    31081 actattgaac ttacaggttc ttttaatgct tctctaactt ctgtagagca tatttctatt
    31141 gttttaggta atcctgagat taaatctcta cctcttattt gcatatttat ttcttcatca
    31201 tctttaaatg tagaacctat gttaattttt acattttcag cagttctttc acctatcata
    31261 agattatatt ctttttttac ataagccact atagactcgt caaattcgtc tccacctatt
    31321 cttatagatt tagcagtaac gattcctcct aaggatatta cagctatttc tgaagtacct
    31381 ccaccaatat caactaccat attaccttct ggttcttcaa cttttaatcc agcccctata
    31441 gccgctgcca ttggctcttc tataaggaat gcatctttag ctccagcttg tcttgcagcc
    31501 tcttctatag ctctcttttc tacttctgta actccaaaag gaacacatat agctattctt
    31561 ggacttacaa cacctttttt atcagccgct ttttgtataa aatagctaat cattgattga
    31621 gttatgtcaa aatcagctat tactccatct ttcataggtc ttatagctac tatatttcct
    31681 ggtgttctac ctatcatttt tttggcttct tcacctactg ctaatacctc tttactatca
    31741 tctcttattg cgacaactga tggttctcta acaacaatac cttgtccttt tatgtaaact
    31801 aatgtatttg cagtccctaa atctattccc atatcctttg tcatcttatt aaaactaaaa
    31861 aaaccttttt tttctttctt tttttcctta gccatgattt tactccttcc tactattaag
    31921 aatcatgttt aaaacattct cctattattt tatcacatat aaagtcaaat tatcatattt
    31981 tctttaaagc taaagtataa tccatctcca ataattatat ggtctattat ttctattcca
    32041 attatttctc cacatttaat aagtcttgat gtgatatttt tatcttctct tgatggttct
    32101 acacttcctg aggggtgatt atgcatcact attatcttac ttgcacttct tcttatagct
    32161 tctttaaaaa cctctcttgg atggactaat gacgagctta aagtccctat agatacatct
    32221 acatcagata ttatctcatt ttttgtgttt aaaagaactg ctttaaaaac ctcttttttt
    32281 aaatacctta ggctatccat ataatacctc tgtatatccc aaggattcct tattttatac
    32341 tttataggtt taaaactagc tactctagag cctagttcta aagctgcttt aatttgggtt
    32401 gattttgata acccaattcc atctatatta cacagctcct ctattgtcat atcttctaaa
    32461 tgtctaatac cctgaatatc tctatttatt atatagttgg ctaattcaat agcattttta
    32521 ttcttgttgc cagttcttaa aagtatagcc aacaactcag catttgataa gctttttacg
    32581 cctttggcaa gcatcttttc tctgggtctt tcctctggtg ccatttcttt taccttaatg
    32641 gttgaattaa atgacttttt cagataaatc acactccata aaaaagattt atactaaaat
    32701 atttttttaa taggtcgcct aaccttgaaa ttggaagacc aactatatta aaataatctc
    32761 ctctaatttc ttcaactaac aaagctccat aaccctgtat accataggct cctgctttgt
    32821 caaatgactc attagttttc agataatcct caatatcctg ctctgataac gttttaaatt
    32881 tcacattgct gattacatag tcaattacct ttttatcttc gcacaagttt attaagctaa
    32941 tacctgttat gacttgatgc tctcttccag atagtctttt taacatatct cttgcacaag
    33001 actcatcttt tggttttcct aaaatagcat tgtctaaaac aacaactgta tcagctccaa
    33061 taacaacatc ttcattatgt tcagatgcta cagacatact tttttcaaaa gctaatctca
    33121 taactaaatg ttttggtgtt tcaccttcca atataatctc atcaatttca tttttaatta
    33181 tatcaaatct tacattcgta ttctctagaa tttctttcct tcttggagag gctgatgcca
    33241 agattatatt catttattca cctcatttgt acgtaatttg tacctattta gtctatcact
    33301 atattgtaaa aaattcaaca gaaatgtcga accttttttg ttacactatt gttatattta
    33361 ttaccattag aataaatata cataaaatag aggtatggaa attattccat acctctgttt
    33421 tatgtactca ttagagatat ggaaattatt ccatatcctt attttgtcca tattacaaaa
    33481 ttttaatagc tttctttgga catttttcca tacataaatg gcatcctaca catttatctg
    33541 catctacctt atgtttttct tttaattctc cctctattgc atcaaactta cattgttttt
    33601 tgcacactgt acatccaaca caaagttctt ggtcaatagt aactttcttt ttcttagtta
    33661 tgtcacctga tattactttt gtagggcatt ttgctacaca ttgcatacac cctacacact
    33721 tattagggtc tatcttagct attttgtctt caaatattat tgcatcaaat ttacaagctt
    33781 ttacacacat tccacagcca atacatccag cagtacattt ttccttaaca gctttaccaa
    33841 actctttgct attacactct acaactactt cttgactttc tggttttgtg attattatac
    33901 ccttaggaca aacttcttta cattttccac aatttacaca cttttcttca tctattactg
    33961 ctattccatc aactatagaa atagcatcaa atttacaagc atccttacat gttccaagac
    34021 ctaaacatcc aaatttacac atcttagcac ctgagtttaa aacatttgct gctctacaat
    34081 ctgatattcc ttcatactca tatttatctt ttgcacttga acaagttcct ttacaaataa
    34141 cttttgctac ttgtttctca cctgcttcag cacttattcc cattatttct ccaacttttg
    34201 caccaacatc tgctccacct acagggcaac cattaactgg tgcattgcct tcaactatcg
    34261 catttgcaag acctccacaa cctggaaatc cacaacctcc acagttggct cctggaagta
    34321 ctcctagtat agcttccact ctctcgtcta cttctacagc aaacttttta gatgcgaaat
    34381 ctagtactat cccgaagatt aagcccataa ttcctaaaac taatacagct gtaagtatca
    34441 ccattttcac ccctcttttt tatagcttta taagtcctgt aaatcctaag aaagctattg
    34501 acattaaacc tgctgatata agcgttatag ggaaaccttt aaatgcttct ggtatatcag
    34561 ctaactctag tctttctctt atacctgcga atattactat tgctaaagta aatccagctc
    34621 cggctccaaa tccatttatt attgtttcta ctaaattata acttttttga acattaacta
    34681 gagctatacc aagaactgca cagtttgtag ttataagagg taaataaact cctaatgctt
    34741 gatataaaga tggactcatc ttttgaatta ccatttcaac gaactgaact atagaagcta
    34801 taaccaatat aaaagctatt gtttgtaaga atccagttcc agtttttact aataaaatct
    34861 gtataaaata agttataatt gaagctagag ttaaaacgaa cgtaaccgca actcccatcc
    34921 ctactgctgt atcaaccttc ttagaaactc ccaagaaagg acatataccc aagaattgag
    34981 atgttataac gttattaaca agaacgatac ttaaaaataa aagtattaaa ttcatttatt
    35041 acacctccac tatgcttttt tacttcttaa tttattaaat cctgcaaata agaatcctaa
    35101 tgttaagaat gcacctggtg gtaatataaa tattaatact ggttggaaag atgctccaaa
    35161 taatgtcatt ccaaataaac taccatttcc aagtaattct cttactgcac ctattattgt
    35221 aagtgcaaca gtaaatccaa gaccttgacc tacaccatca actattgaag gcatagctcc
    35281 tgttttgaaa gcaaaacttt ctgcacgagc taatattaaa cagttaacaa ctattaatgg
    35341 tatatatata ccaagagcct tatcaagagc aggaacatat gcttttaaaa gcatacctac
    35401 tattgtaaca aatgtagcta taactactat aaatataggt attcttatct tatctggtgt
    35461 aatttttctt attaaagata taactaaatt tgcacatatt aaaactgctg ctgttgaaag
    35521 acccatacca attccattta ttgctgaagt tgtaacggct agtgttggac acatacctat
    35581 aacttgaaca aatgttgggt tctcatctat tagcccattt ttaaatactt tagctaaatt
    35641 cataattaac cctccttatt tattaagagc actattgaaa acatctatag cagcatttac
    35701 tcctgtagta actgctgtag atgtaatagt tgcacctgat attgctaata tttgattatc
    35761 tgctgttgta cttccttttg ctacttcaag aggctcagca gtttttcctt tgtattgacc
    35821 cttaaatgca tcatccttag cttttgctcc aagacctgct gtttctgaca tattaccaat
    35881 gtcaacacct gtaacttgac cttcagatga tatacctacc ataacttcaa tttctccacc
    35941 atatccactt ggtttagctt ttaaagtata tccaaccact tcagaaccat ctaaaccttc
    36001 atacacttca gctataagac catctccaag gtctttatat gtacttttat ccatttcttt
    36061 aaattctttt gcttctggaa ggactgcttt tctaagttca ttattttctt gtatatttct
    36121 ttgttctatt actggagctg taacctgatt agtagctcca agagctaatg cagctattgc
    36181 acttatagca agtaaagtac cacctaatct caccatactg ttcattattt agccacctcc
    36241 ccaaatactc tatttctaac aaacttatct ataagtggag caagacagtt cactaatagt
    36301 attgagtaag atacaccttc tggatatcca ccatacattc ttataacagt tgttataaga
    36361 ccagctaata cagcgtatat tatttgacct tttttagtca taggcgaagt tgtataatcc
    36421 gtaagcatga agaatccacc taacataagt cctccagcaa acagttgata tattgcgaaa
    36481 gttatattaa atccacctaa aaggaatgtt aatataaata cagttgctat gtaaaatact
    36541 ggtataacat aatttattat gcctttatac attaggtata ctccacctaa taataataat
    36601 attgctgatg tctcacctat acatccacca atattcccta tcatcatgtc agcaagacta
    36661 attccattgc tagaaaggtc tgccagtcct gctgctccat ttttcaaaaa gcttaatgga
    36721 gttgctgtag taactgcatc taaattttta cctatccagt taacacctgg ttgagtccaa
    36781 gcagtcattg ctactgggaa tgatgctaat aaaaatgctc ttgcagcaag tgctggattg
    36841 acaaagttac atccaattcc accaaatacc attttaacta ctaatattgc aaatattcct
    36901 cctactagac acatccacca aggaagtgat gctggtacgt taaatgctaa taataatcct
    36961 gttacaacag ctgaaaaatc tcctatagta cttttttgct tcgtaaattt ttgatataaa
    37021 aattcagtac ctactgtacc aagtatacaa aaaaacatag cactcaaagc attaagtcta
    37081 aagaagtata ctcctgctac tgctgctgga aggagtgcta taataacttg tttcattata
    37141 tatgaagtat cttcattact tctcacatga ggagaagatg atactatcaa cttattttcc
    37201 atcgtttttc ccccttaact ttctttattt ctgagcagct tgctttcttc tctttgctcc
    37261 tatttctctc tttgctgatc ttatagattg aagtaatggt cttcttgctg gacaaataaa
    37321 tgaacaagac ccacattcta tacaatccat tgctctatga tattcagctg tgtcatagtc
    37381 atcttttaaa gaatatgcac ttatgaaaag tggttgtaag aatgatggac atacatctgt
    37441 acatcttcca catcttaaac agttttgaat atctggagta cgtgattctt cctcatccaa
    37501 gcataaaatt cctgaagaac ctttgttagt cgctatttca gtagtatatt gagctattcc
    37561 catcataggt ccacccatta taaccttacc aatcttctta tcttctttaa atccaccaca
    37621 ttgttctatt atttctgaaa ctaatgttcc aacttttgtt attaggttct ttggctcttt
    37681 gatgcaacta cctgttattg tagtgattct ttcaaccaaa ggcatacctg ttttaataga
    37741 cttagctatt tgtgctgctg tggcaacatt gtcaacaact gcacctgctg ctattggtaa
    37801 tccaccagat ggaacttctt tgcctgtaca cgcataaata agttgtttct ctgctccttg
    37861 tggatatttc acttgaaggc caacaacttc gatttcacta tagtctttag ctacattttg
    37921 aattgcttct atagcatctg gtttattcgt ttcaattcct ataaatcctt ttttgacatc
    37981 taataccttc attaatgctc ttaaaccaaa cacaacatct tctggatttt caaccattaa
    38041 tctgtggtct gcagttaagt atggttcaca ttctgcacca tttaatataa ctacttctgc
    38101 cttgctatct ggtggaggag atacttttac atggttaggg aatgtagctc cacccatacc
    38161 tactattcct gcctctttta tgatacctac tatatcttct ttgctcaaat cctctaactg
    38221 accttttggt tgaacactct catgtaattc ttccttaaag tcattttcga taactacaca
    38281 ttgagctgaa cctcctggta cttcatgttg ttcaatagca ataactttac ctgatactga
    38341 agaatgaacg ttacatgaaa caaaaccttg ttgttcacct attttttgcc caaactttac
    38401 ttcatcacca acttcaacaa taggtttagc tggtgcccct atatgttgct gaagaggaat
    38461 gtaaactatc tttggagctt gagctttttc aagtgccttt gtgttagagt actcttttct
    38521 atatggagga tgtatccctc ccttaaaagt taagagtttc attgttttac ccccttatct
    38581 ataaaaaaac attttttctg ccttctataa gtatactata tatattaaaa aatcttaaca
    38641 attgttaaaa aaatatccgt atttttataa tttattttat aaatcaatac ctctatatta
    38701 agtcaaactg aggaaaagga ttgcttaatt aaacaatcct tttcatatag ctttctaaag
    38761 tccaaatttt ctgtatttta ttttatagaa tttataaaca tagagtactc ctgcatggat
    38821 gataaaagca gacttttact tacactatat ttttcttcat ttgctgcttt tgaagctgta
    38881 tcaatttttt cattcacatt ctttacatac tctattaaat tatctttaaa taaacgcatt
    38941 tcagaatagt caatcttttc agcttctttt gatatatttt gtgatattgc ctttctattt
    39001 gtcaaaatag tattatattt ttccatatct acattatttt cagcattcga ccaaaaactt
    39061 gattcttctt taaagtttgt tattaattta tttaattctt tagatatact ctctatataa
    39121 gcgtagttac ttgtatactc taaagacaac ataggtgcat ctaagtgtga taaaaatgca
    39181 tctggaaaca cctttcttac actgcttatc tgctttctaa catcattttc atcaaaagag
    39241 gaataggtct gtattttttt tactccatcc ttctccataa ctgaaaaagg tatgtcatta
    39301 ttaactaatg atgtctgtat ttttttcaaa tcatcattat tatctattgc agcaacttga
    39361 atagtgtaca tatcccagcc ttctatagta gctaatttga cttcttctgg ctctttagtg
    39421 ttatttaccg ctttttctgg attagtttct tgtttatcat ctgaattggt ttgtgattta
    39481 gattttttcc ctttttttat tgaatttaat tcatcagata tatctttata agttatatct
    39541 gatgaattat ttagaaatgg tattttagcc gatacatact ccaatatctt gctatctttt
    39601 atttttgtat aagaataata gccaattaga cacaagcaag caatcgttat aacatattta
    39661 cgtaaatcaa tcttatgtct attattatta aatcctctgt atatcgtttt tcttctattc
    39721 attagtttgt ccctcccaaa attatattat taataaagta tatttttaag agtcacaatt
    39781 tatgaatata aataattatt tcttctaatt ttttaataag aaattgtact tactaaacaa
    39841 atcttcttgc accaagtaat actttagacc aatatgaact agttaaatta tccactttaa
    39901 ccttattagg attagtctga gtaccactac aatggataaa tttactattt cctacatata
    39961 tacctacatg attagttgtt ccatcaccat cagtgtcaaa ataaactaaa tctcctggtg
    40021 cataattccc catagaaatt gcacttccaa aattagcctg ttctctagaa actctaggaa
    40081 tagaaacgcc tacagaatgt ttaaaaacat actgtgtaaa tccagaacag tcaaatttat
    40141 caggtcctga agctccccat tgatatggta ttccaataag agtatatgca aaatctacga
    40201 ttgttgaacc ttttgctgta gatttatctg aatttccagt aaatgatggc tttgagttac
    40261 tattagattg agaattttgg ttagatgatg aatttggttt ttcttttgta ccttcattag
    40321 tctcagaaat ataactggca ctcacccatc caattgttcc actcgataac tttaccttat
    40381 accaaccatt atttttggat tttaattcaa caacatctcc accatttaat tttcctatta
    40441 tagaatagct tgtcccagga ccacttctta catttaaact cacagcagat gttaccttac
    40501 cattcttgcc ttcaattgat tcttcgctag atggtttttt atcagaatta ttagtactat
    40561 ttgaattact agaattattc gttccaacat cctctgatgt tttagagata tattggctac
    40621 tagcccatcc agtaactcca tttgatagtt ttattttata ccatccattg ctttgttcta
    40681 gtaactttac tacatctcca ttatttgctt taccaactaa tgaatagtta gtacctgcac
    40741 cacttcttac attcagtcta gaactcacat ttactttacc atttccacta atagttgtcc
    40801 cacttgaagt tggattattt tgatttgatg taccttcaga tgaaccactt gttgatatgt
    40861 attttgcgct tccccatcca acaacagaac tcgataccct tactttatac catccattag
    40921 acttttctaa aatctctaca gtttttccct tgtataattt tgctacctta tcacaatcag
    40981 aacttggtcc acttcttata ttcaaggcac ttgctgttac tgttcccttt tcaagagcac
    41041 ttgcatttat ggagctaaca gatactgcta ctgccccaat tcctaaagct gctatagctt
    41101 tcttcactac tatcactccc cccaacaaat ttttatagtc ataaattcat aacattatta
    41161 tccattttta gtccctacaa tttaatgata acttattctc ttattaattg taaagaaatt
    41221 ataaacatat ccttaaaatt aatgattttt aggaagtatt tcaatccaat aattatctgg
    41281 gtccgctata aaataaattc ccatactttc attttcaaaa catatgcaat ctaaatcttt
    41341 atgaagtttt tttgcctcat caaactcctc aacttctaaa gccagatgaa attcattgtc
    41401 tcctaaatta tatggtctgt cccaatctct aagccaagtt aattctaatg tatgactagt
    41461 aataccatct cctaaataaa ctaatataaa acttccatct tctgcttcct tacgctttac
    41521 ctctttaagc cctaaagctt ttttataaaa atctaaactt ttttctaagt tagtaacatt
    41581 gaaattgtta tggcaaaaat taaacttcat tttgaaatca ctctccaatt tttatttttt
    41641 ttatattata tcattattat aaatttattt aaatcatatt aagttaaaaa tttgaatgat
    41701 gatgaccaat taccaaatgg tggtaaatta tttaaaagaa tatgtcaaaa aaagaataag
    41761 ctctttcaaa tgcacaaaaa atttataccc aagttatact taatcatgca aattggcaga
    41821 acttattctt taaaactcta acttttaagt ttttctttga taatataatt tattactttt
    41881 tttctaatat cttcagcatt ataatcatct tctacttcta tatccaaaag ttttgctatt
    41941 gacctcatat cttctctagt ctttgaccta tagcttgata ttaattcatc ttttattttc
    42001 tctggttcta aaagatattc ttcatctcct cttttgaaaa caacgtattt ttgagcatat
    42061 gaacttctat tatagtatat atatcttgat atttttctta aaatttgatt atatgaaagt
    42121 cgcttgttaa tatcaagttt taagtactct gaaaaagcaa atagctcttt ttttgattta
    42181 aataatgctt ctttctttat agtccttgat attgaagtta cactttcttg atatgcacac
    42241 ttttttaaca tttttaaata tactctatta agaccaatac tttgattgaa tttttttata
    42301 ttattattaa taatcttatc caagttacct tcaaagtatt tttttgctcc tttttgtgat
    42361 acataactct caagttcttt gtgggccata tcaagtatca ttttttttaa atcctcttta
    42421 tatcccctag attccatgat actccctccc ttagctattt atagtatatt caaaaagctc
    42481 aagaaatgtg agtcattaca aaattttttt actttttatg tatatattaa tttaaaaggg
    42541 gagataatag taatgtaaaa tcaaacatac tcaatctccc ccatttttag acctctatta
    42601 ctcccccaat agaggccttt ttttagttta tcaatttcta ttcaattccc tttagttcaa
    42661 atcctaattc tgctatcact tcttttaatt tttcaataga tatatcatct ttcatatcta
    42721 cagatgcaca cttattttct aaatccacat ctaaaacttc aataccatct atatcttctg
    42781 ttaatgcagt tttaagatgg tttacacaat gaccacaact cataccttct actaatagtt
    42841 tcttcttcat ttaattacct ccttataccc cataagggta ttctatcata tagtttatac
    42901 tttttaaata gaaattaatc atttaatttg attcattcga ttttatatct aaattagata
    42961 ttccctcata tacatcaaaa tcatttggag taattttacc ttttaatcta ctattactta
    43021 caatatagtt gtttctcaca gctaaactta taaatgttgc attatctttt atatatgtct
    43081 gtacatcttt gtatgctttt tttgtttcaa tttcagacgt agaacttgta agtgcagaca
    43141 tatatccatt tagcttatca tcagtatatc cactacttgc tataatacta cttgcatctg
    43201 gtataattga tagtttccat ccaactaatg ctaaatcata atttttagaa ttaagagcat
    43261 tttccatatc cttatctgac agctgattta ctgtactatt tattcctata gcttttaagt
    43321 tttcatttat tatgtttgca gtttttattc tctcactatt atctctgttt actattatct
    43381 ttaagttcat ttcagaaaga cttttcttta cttcctcttt ttctctattt tttttctttt
    43441 cagcttcttt tttgattcta tcttcttctg cttttttagc ttttgcttct tcttctggcg
    43501 taagcttctt tgagttcttt ttagctgatt ttttctgatt ttttacttta ttgtcatttt
    43561 gatttactga gtttatattt gcatattcta ccttagcaag acactctatc gccttatctt
    43621 tattaaactc taaatccttc atttcactat tatagtattt tgattttgaa ttaagtggaa
    43681 aattaactgg agtagcatca tccatataac cttcactaat aattctatct ttatctatag
    43741 agtgagcaat tgcttttcta aaattaacat ctttaaaaaa tggattatta taattaaata
    43801 atacacactc ataatctctt ccttgatatt ttgttatatt aaactctttt tcttgaaact
    43861 tgcttaaatc atttaatgta acattggtta tatcactatc aagagccata accatagatg
    43921 tccttgcctc ttcattaggc accataccta cttttatgtt cttcatggtc tttggaactt
    43981 cttcatagta atctttgttt acagataaaa ccattccttc tctttctgta tatgattcta
    44041 ttttatattt cccatttcct atcatattat tattcttgtc atttacatcc tttgaatcta
    44101 aatgattttg agatacgatt ggaaaaatta aactatcaat tgaaaaagca tatctagctt
    44161 taaattttat tgtaaaatct ttatctgatt taatattcac agaagctata tttttagtaa
    44221 attcattata tggactatct gcactttttt gaattaaacc aatagtatag tttacatcat
    44281 ttgaagtaac attttttcca tcatgccact ttgcatcttt tagctttata tctatactca
    44341 ttccatcctg agctatatta tactccttaa ctaattgagg aattacattg tagttctcat
    44401 ctatagtaaa taaactatca taaactaaat tcattatata accaacagac ttatcagtat
    44461 tagttatagg atttatagtt tttggagtta ccattgttaa gtttatatac ttagcatcta
    44521 tagaactttg actttgtaaa cttgaatcac tactactttg ttttgtttta gtattactac
    44581 aaccagctac cataagagtt atagctaaaa cgactgttaa gacttttatt ctcttcatta
    44641 gttttttcct ttcttgccat atatcttatt ataatgttcg taattatttt ttactttttc
    44701 tacatatttt gaagtttgct taaaaggtat atcatgtaga ttttcgccat ctttactata
    44761 ttcattattt tctaaccatt ttttcacatt acctgaacca ccattatatg cagctatcac
    44821 taaatctaat ttaccaaatt ctttgtataa cttacttaaa taccaacagc caagtcttat
    44881 attagtctct gggtcgaaaa tatccacatt ttttaaattt agttcctctg ctccccaatc
    44941 tctagttata tctaatattt gcattaatcc ttttgcttcc ttttttgaaa cagcagaact
    45001 attaaactta ctttcggctt taataacact gtaaactata ttttcatcta aattaaattc
    45061 ttttgaatac ttttctacat actctgaata ttttttagga tataaaaatt tatgtattac
    45121 tttgctttcc attaatagtg ccccaaataa gattataaaa atagatagaa tcaatacttt
    45181 cttactattc acgccaattc tccttcatgt actcaataaa tttatgtgct ttactttcta
    45241 attcagttat tgttcccgaa ttatctatta tataatcacc atatttggat ttttcttcct
    45301 gactcatctg tgaatttatc ctactaagtg cttcctgctt actacaatta tctctctttt
    45361 gtattctact aatttgtact tcttgtttgc aagtaactac taatagcttg tcaaccatat
    45421 ctaaaaaacc actttctacc aatattgctg catctaatac tactatattt tcgccttttt
    45481 ttctcaattc ttctatttca cttattattt tttctcttat tcgcggatga gtcaagctat
    45541 ttaattcctt aagtttttct tcatcgctaa aaactatttt cccaagagct tttctattta
    45601 gagttccatc atcatttttt atactttgcc caaaatggac aaatactttt tccaataaca
    45661 acttatcctc aaatatcttc ctggatataa tatcagcatc cactatagaa atattaagat
    45721 ttctaaatat atttgatagg ctgctttttc cacagcctat tcctcctgta agtcctaata
    45781 tcaacataaa atcacctact ttgtctcata ccaagaacta cctacattta aatctacatc
    45841 taagtgaaca tccatattta cagcattttc catttcttct tttactattt tcttaactat
    45901 atctatttca tcatcaattg cttcaactat caactcgtcg tgaacttgta gtataagttt
    45961 tgatttcaaa ttgttctctt ccaatttttt atgaacattt atcatagcaa tttttattat
    46021 atctgctgca cttccttgta ttggtgcatt cattgcaaat ctctttcctc tatttctttc
    46081 cataaaattg cttgacttta tttctggtat atatcttctt ctgtttaaaa ttgttacagc
    46141 atatccatcc tcactagcct tttctactgt tgtgtccata aactctttta ttttatggta
    46201 tttagcaaaa taactttcga tatattcttt cgcctttgga acaggtatat ttaaatcatc
    46261 agctagacca aagtcacttt taccatatat aataccaaag tttacagctt tagctgcacc
    46321 tctcaattca ctagtaacat cttccatagg aacattaaaa acttgtgaag ctgttttggt
    46381 atgaatatct tcatgatgtt taaatgcttc tatcatattt tcatcctgac tcatatgtgc
    46441 aagaactctt agctctactt gtgagtaatc ggcatcaacc aacttacagt tatcatctgc
    46501 aataaacact tttcttattt ttctacccat ttccattttt ataggtatat tttgaagatt
    46561 tggttctgta gatgaaattc ttcctgtagt cgttatagtt tgattaaatg atgaatgtat
    46621 tctattactt tctggattta ttatatttaa aagtccttca acgtaagtag aatttaactt
    46681 tactatttgt ctatactcag ttatcttatc tattattgga tgcttatctc ttaatttttc
    46741 taaaacatct gcattagttg aatatccagt tttagttttt ttaattattg gaagctctaa
    46801 tttttcaaat aatataacac ccaattgttt tggtgaattt atattgaatg gctctcctga
    46861 taattcataa atttcctttt ctagtgtagc tattatttct ttaaactcta cactcaattc
    46921 atccaatata cttttgtcta cttttatacc ttcatactcc atatgaccta agacttctac
    46981 taaaggcatc tctacatgat aaaaaagacc atccatactc atatccatta gacttctttc
    47041 catcatagga attgtttctt taactgtgca tattatttga cccatatact ctgctaaatc
    47101 ctcaaattct aaatcctcat agtttttaga tttaacaccc tttcctaata attcttcttt
    47161 tgatttaacc ttttttgata aatacttcat agctattgca ctacaatcat atgaggtaga
    47221 tgaagttgaa tctattaagt actcagctat tgttatatca aaatacatat tttctaagtt
    47281 tatattatat ggttttaaag atatataatc atcttttaaa ttatatccat actttttaat
    47341 ttcattattt gaaaatatac tatctaactt tgacacttca tttgaatcta cataatatat
    47401 tttttctcca tctacactta taaaaatata tattatattt ttttcaagta tattaccttg
    47461 tcctctaaca gtttttaaaa taacttgtcc ttttttgttt acttcatcta taaatttttc
    47521 tgtatctttt aattttaata tttctatttt ttcttctacg tgttctgtgt catctgaatc
    47581 gaccaaatca actaatcttg ataagagact tgtaaatcca aagtatctaa atttatctaa
    47641 aagttcatct ttatcataat cgccaaaaac catactatct aaatccactt ctattggcac
    47701 atctcttata attgttgcaa gtcttttact ttgaatagct atttctttat tttcctctat
    47761 tttctttttt acactacctt taagcttatc tgtattctct attaaattct ctatactaga
    47821 aaactctttt ataagcttta tacctgtttt ttcaccgatt ccaggtactc caggtatatt
    47881 atctgactta tctcccataa gaccttttaa atcaataaat tgtgctggag tcatctcgta
    47941 tttttcaatt acagaattaa agttgtattc ttcaacttct ccaactcctt tttttgttat
    48001 aagagtagtt gtattatctg aagcaagttg aatagcatct ttgtctccag ttactatgta
    48061 taccttatac ccattatttt ctgctttttt agaaacagtt cctataatgt cgtctgcctc
    48121 atacccatct atttccaatc tatttatttt gaatttatct aaaaggtctt ttaatggctg
    48181 taattgttct gccagttcat ctggcattcc ctttcttcca gccttatact ctttatattc
    48241 taaatgtcta aatgtaggtg cttttctgtc aaaggctaca cttatatgtg ttggtttata
    48301 tatatctatc attttaaata gcattgttgt aaatccatat attgcattgg tctttaaccc
    48361 ttctttatta ttcatttctg gcagagcata aaaggctctg tttattattg aatttccatc
    48421 tattataatt aatttttttt ccaaattata tcactcctaa aaattatcta tttttgtaac
    48481 atatatatta tataccaata tagtgttatt taatattccc ataataataa tagtatatta
    48541 aaattaaata tgttgcaaac aatatatttt tttgctataa taatatacat gacatgcccg
    48601 aatggttgaa ttggtaaata caatggattc aaaatcaact gtgttgattc ataagttttt
    48661 ataatgtttt acagtttgat gagtattttg tattcaatat tcctcttgca tattcttgga
    48721 aaatctggta ggatatacaa gtagtttgga tttaaaatat aagccgctgt ggcggaactg
    48781 gcatacgcat acgactcaaa atcgtacggg aaaccatatg ggttcgagtc ccatcagcgg
    48841 caccaataaa aaaaactctt tagtatatac taaagagttt ttttattgta atattctttc
    48901 atctttattt ctagccttgt ataagtataa ataccatagt cataacttct tgaactccta
    48961 aaatatatct aaacaaagta ggatttttta tgtattcact taataaatcc atacttctta
    49021 tcatattgat tttttcccaa tctctaaaaa ttttgataca aataaaaaat acagagaact
    49081 acttgatata ctagaaggtt attctgtacc atttggtatt gctgtaggtg ttccagatgg
    49141 aaatttacca aatgctagag atgtagttta taaagtttct agagtttagg ataaagtgtt
    49201 gcaacaatca attagttact tgaagagtta aatcagtaat atacaaataa attaatggaa
    49261 gaggaagcta tttaaaaagt agtttagatt tttcattgta aaataattaa ataaagaata
    49321 aggtgataag tattttattt attatcttat tcttttttat ttgtggaatg ataaaaataa
    49381 gaattaagtg taatacaatg taaataaaat gtgttaattt taagtatat
//
LOCUS       DAMJYN010000022        48842 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.022, whole genome shotgun sequence.
ACCESSION   DAMJYN010000022 DAMJYN010000000
VERSION     DAMJYN010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 48842)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48842)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48842
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.022"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            144..1361
                     /locus_tag="PC466_001362"
     CDS             144..1361
                     /locus_tag="PC466_001362"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase"
                     /protein_id="HDF2768753.1"
                     /translation="MMNVTLTDVKEARETIKNIVKRTDLLESVKLSEKTGANVFYKCE
                     NLQKTGSFKLRGACNKIASLTDEEKANGVIASSAGNHAQGVALGAKMTGIKSTIVMPA
                     TAPLAKVSATKGYGAEVVLNGAVYDDAYAKAVEIQKETGATFLHPFNDKYVIAGQGTI
                     SLEIFEQLDNKVDTILCPVGGGGIISGVAVAAKALNPNVKIVGVQTANIPSMKESIKN
                     GKVTTAFNDTTIADGIAVKTPGDLTFEIINELVDEIVVVEETEIAESILFMMESQKIV
                     SEGAGAVCTAAILSGKYVPAKDENVVCIISGGNIDINTLYRIIGVALAKEGRRYSFST
                     IMEDKPGNFAELTRIISENGGNILSANQGKLSAGEALGKQSAEFILETIDYDHIARIK
                     KAIEEKGFKIIEL"
     gene            1456..1836
                     /locus_tag="PC466_001363"
     CDS             1456..1836
                     /locus_tag="PC466_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HDF2768754.1"
                     /translation="MKHEVIHTNDAPAALGPYSQAIKAGNLLFVSGQVPLVPETMEVV
                     EGDVQAQTAQSLKNLKAILAESGADFSNVVKTTVFIKDMNEFGAINEVYAEYFGENKP
                     ARACVEVARLPKDVKVEIEVIAVL"
     gene            2120..2602
                     /locus_tag="PC466_001364"
     CDS             2120..2602
                     /locus_tag="PC466_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF2768755.1"
                     /translation="MLNFFKKNKSYKLHAVVSGNSINIEKVNDSVFSKKLMGDGVAII
                     PNSNVVVAPCNGKVTVLTESKHAFGMVSDEGVEILVHIGIDTVNLQGEGFKNEVSQGD
                     TVKKGSPIISFEREKINSQGIDCTTIIIVLNHSEFSEINCMVENEVVAGQDTVIEIMK
                     "
     gene            2623..3438
                     /locus_tag="PC466_001365"
     CDS             2623..3438
                     /locus_tag="PC466_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDF2768756.1"
                     /translation="MRVVKIFNNNALSTVTNDRKEAILLGLGIGFNKRPGDKVNEDKI
                     EKIYYVQDHMQTKFLELLKNVSPEVMDASQQIISLIPGNEGKFNNKGILSLVEHISFA
                     IDRMKNNVFLPNLMLLDIKMMYSKEFELGVKALEIIYRVCHIHLPEDEAGYIALHFVN
                     LQSNDNLAYDTLKFVKGSIDLIKECYGLELDESSLSTLRFRTHLKFLAQRIFKNEICQ
                     DDKMIEMYDYLINNHPKNKEYLEKLNVYIEKEFRYKLDKPEKIYLLLHLTKIL"
     gene            3489..5039
                     /locus_tag="PC466_001366"
     CDS             3489..5039
                     /locus_tag="PC466_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDF2768757.1"
                     /translation="MKEKLLGGLETFAKAMVQPLMYLSSAGILMVVGVLLTNDMLLGV
                     LPFFKWEPIQIFGSLIYNCIMAIINNLAVIFAIGIPAALAKKEKHKAALIGFMSYIIY
                     LTASNTMLTSLGQLAKESKMLGLIGTGQATILGIQVVDTSVFGGIILGCIAGYVFNRT
                     SNKTFKGALQIYSGANFSFICMFFVSILIGVVSNFIWPLAQQGIASLANVIKDTGTFG
                     LFLYGFLERILVPTGLHHLIYTPFQFSDLGGVLKVGADTVSGAYAIVMTEMNLPVERF
                     SDSIYYMATGFTKMFGYIGIGAAFIYTAYKQNKKKVKATIIPLIITAVLASVTEPLDF
                     MFVFCAPLLFFVHAVIAGLFIALLKIFDVTALCGGNLLVSIIMNTTVGVEKTHWPVMM
                     ILGLAQIIVYFVVFSFLIKKFNYKTPGREDESTATGEEQSKQLNLDAGIENIIDGLGG
                     KENINTVENCITRLRVNVKDESKINEDIINLTPNSGIVRKGKDIQIIFGLHVHEVRRA
                     VEDFLEAY"
     gene            5136..6488
                     /locus_tag="PC466_001367"
     CDS             5136..6488
                     /locus_tag="PC466_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HDF2768758.1"
                     /translation="MIITIVGGGSTFTPGIVKSIALREKELELEEIRLFDIDKERQDK
                     VAVVVNWILKEDVKTDVKLTVTNCEKEAYTDATFIFAQMRVGKYEMREQDEKIPLKYG
                     CVGQETCGCGGMAYGLRTIQPMIKVIDDVEKYAKKDYWILNYSNPAAIVSEACRKLRP
                     NARIINICDMPIAIIDMIAESLNINDVHNIRYDYFGLNHFGWFTSIDYKHRDLMEEIK
                     EYIKENKILLPKSYIENLNKSRSTGNRHAVSSWIHVWESVYTMLESFPKYLPNTYLTY
                     YLLSKETVEHSNINRTRANEVMESREKDLFEGVRHYLETGEISEKVFYAGSHGDWISD
                     LAVSIKNDTRSRFLVITENRGAIPNMPYDAMVEIPAYIGKDGPEVIARGPIPLFQQGL
                     MMQQLNSEKLIVEAYIENSYEKALQAFTLNKTIPSMNVAKEILDEMIEVNKEYWPELR
                     "
     gene            6619..7377
                     /locus_tag="PC466_001368"
     CDS             6619..7377
                     /locus_tag="PC466_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2768759.1"
                     /translation="MNIINKIFWQEDRIGMITNNLEADTHSHCMLQLFLGIEDSIEIT
                     VNEKLVKCNCIIVDKNISHSFSARKKVYYSAIIEPTSIYAEQLTSKMNDFGYWICDND
                     GLEKLRQQGTFLIYNSSKEQYLRFMEMLNNYLNIPITLKHYDDRITELLNLLRTCNCD
                     NHTISSFADKVSLSASRLSHLFKEQIGIPLKSYILFHQMECAFRELLSGKNVTEASMT
                     AGFDTPSHFAGTVKRMMGMPVSLSLKDSEFLKVY"
     gene            7424..8143
                     /locus_tag="PC466_001369"
     CDS             7424..8143
                     /locus_tag="PC466_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="HDF2768760.1"
                     /translation="MNKEYLEETKMLNYNEPQLKLLVSSKNWLELDDFHKIKSIYEFV
                     QNDILFGYNASDMLSATQVLNDGMGQCNTKATLLMALLRAVNIPCRLHAFDVTKDFQR
                     GATSKLISLLAPKYILHTWVEVFYQDRWIALEGVITDKKYLEAIQKKFFNHGGTFKKY
                     AIATNDLKNTSIDWDGKDTFIQKEAIVYDYGIFPSPDVFFSTHSQHMSKLKNFIYVHL
                     IRKIMTKNVCKARNNYIDKNE"
     gene            complement(8267..9667)
                     /locus_tag="PC466_001370"
     CDS             complement(8267..9667)
                     /locus_tag="PC466_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HDF2768761.1"
                     /translation="METQSNNKKGNLIIAIVMTGAFISSLSQTLLSTALPNIMSDFKI
                     TADIGQWLTTIYLLIAGIIVPTTAYLINRFSTRKLFITSMSIFSIGCIIALFSNNFST
                     MLIARVLQAMGSGSLMPLLQVIILYLCPEEKRGAAMSLVGITVGFAPAIGPTLSGWLV
                     DSFGWHSLFLFLSPIAILDVILSFILLRNVGETQKLKLDIPSIVLSSLGFGGLLIGFT
                     NQGNYGWTNIATYLPILIGIMSLILFTLRQLKSKEPFLELRVFKNKPFLISTILIMIV
                     YASMMSATLMIPLYVQSVRGFSALSSGSLMLPGAILMVVLNPIAGRHLDKYGPHALSI
                     LGTGCLFLGTLSFAFLGRDTSLIHVSLMYCIRMIGISMVLMPLTTWGIKTLDRELISH
                     ATAINNTLRQISGAIGSAILITIMTSATKKAHMSSNMLSNIHGIDVAFSIAATLAFTG
                     LIVSICFIKRHQIIRS"
     gene            complement(9671..10579)
                     /locus_tag="PC466_001371"
     CDS             complement(9671..10579)
                     /locus_tag="PC466_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2768762.1"
                     /translation="MKGDNKVTEKQRLIINIAQKIFDQKGFQNTSISDVVKECKMSKA
                     TFYKHFETKESFICEIINYYDEKFLEIIHSINENNDIPSSEKLNRKIIAVWKNIFSRT
                     TINTYIRENFSEEQRKATSKLQTKSRANLLNEYKLSLFDNYGDKIEKIIFDLVFLLDA
                     LIHQFIYIIHVQKREINVYFIAKFTIQILDLVVENMDNLNPLIEKSMFLHKQEDEVYF
                     SLHNKSLFFKTIQDIEELIKTDTSLLENPKLLEAIKKLYVEGKNQQYDSLIMDAMIAY
                     LEKEDTLRPKVLLLNSIKNQLKKETL"
     gene            10840..11487
                     /locus_tag="PC466_001372"
     CDS             10840..11487
                     /locus_tag="PC466_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HDF2768763.1"
                     /translation="MKKKICVAIIFALFIVFVEMFIDSSSEGSKIMTAELSKYRKGVN
                     VLSINNIIVANKKYSLPKDYSPQESSEARDAFYKMNKDAQKSGLNLKAFSTYRSYEYQ
                     DRLFKSYVKEHGEKEANRFSAKPGESEHQTGLAFDIGGDDQSCWANKKFNNTKEAKWL
                     YENAYKYGFILRYPEGKENITGYMYESWHYRYVGTEHSKNFAMNNLTLEEYLHIN"
     gene            11812..14451
                     /locus_tag="PC466_001373"
     CDS             11812..14451
                     /locus_tag="PC466_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HDF2768764.1"
                     /translation="MSYKSTYQEVIKNLDSSLSGLSKERAEELLEKNGANELKEADKV
                     PTYKLFLESFKDPLVIILLIAALVQIFLGETVESIIIFAVIIINSVLGVVQTKKAESS
                     LESLKNLSAPNAKVIRDNKKMTIPAKNLVVGDIVFLEAGDYIPADGRLIEAQSLKVVE
                     GMLTGESEPVLKHTEKISEDVSLGDQKNMVFSGAVVVYGRGSFVVTGTGMDTEMGKIA
                     GLLESAENKLTPLQQKIEDFSKKLGVGIVILALLIFIIQVARNYFMAGNGEMTQIILD
                     SFMFSVAVAVAAIPEALSSIVTIVLAVGTNSMAKKQAIIRKLPAVETLGSTSVICTDK
                     TGTLTQNKMTVVDYYMYGTNNDELDKEKVNYSYHAKLLTMVSTLCNDSHITSDGKEVG
                     DPTEVALINYSSKNDLDYDKLRSKYIRINEIPFDSDRKLMSTVNSIYGDYIMFTKGAP
                     DIVFSRCKYALKNGSKVDITDEIIEEYKHKNEEFSNRALRVLAFAIKDVPEEDFIPSI
                     DDEHDMTLVGIMAMIDPPREEVMDAVKEAKSAGIKTVMITGDHKTTAAAIAKEIGIME
                     EGDLALTGKELDALSEEQLYEKLENISVYARVSPENKIRIVKAWQHKNNITAMTGDGV
                     NDAPALKQADIGIGMGSGTDVAKDASAMVLVDDNFASIVNAVEVGRTVYSNIIKSITY
                     LFAGNLGAIVSIVFAVFAGWSNPFTALQLLFINLVNDSLPAIALGFEKSEKNIMNKPP
                     RHPDESILAGGTLKAVAIRGCIIGVVTIIAQYIGLQVSPELGVAMAFSTLILARIMQT
                     LPARSNNQTVIKLGFFSNKYVIGAVLVCLGLYSLTLIPVLRGIFSIPTTFGLYQLGIC
                     LGLALISSILMELNKLINRSEVK"
     gene            complement(14509..15612)
                     /locus_tag="PC466_001374"
     CDS             complement(14509..15612)
                     /locus_tag="PC466_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate aminotransferase family
                     protein"
                     /protein_id="HDF2768765.1"
                     /translation="MKLKINKAIEMQLKKSYAIESGHSEDVFEIDCGEGINTVSYSSK
                     AVEAFNALKFDMIRGYPHSIALKDNIVDYWKDFIALDTDRICLADGSIHVIYLLNRLF
                     IEKGDKVLGYSPQFSEYETDIKMHGATYDYVLLKKEDNFKFNEKEFIEKINPEYKVIY
                     IDNPNNPTGQIIPLSSIENIVKEAAKYDIAVMVDEAYGEYMPKENSAVKLLNNYDNVI
                     ALKTFSKGFGLAGLRAGYAVLPEQLVSPIKKISTPYEVSEISRSIAANLLDDVQFIEE
                     LKEKTKDIKNQLLIPWKNLNIAETSDTVSIMTVEHKNKDIDLQQEFAKLKIRVISGSD
                     FTGLDKNFIRFRMPEEKELPEVIKAFQIIDNIE"
     gene            15973..16794
                     /locus_tag="PC466_001375"
     CDS             15973..16794
                     /locus_tag="PC466_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDF2768766.1"
                     /translation="MGYKLIVTDMDGTLLGNNHKVTDENKTALQKVIKSGINVTLATG
                     RAFDSAKCNVDFLKEDMPIIACNGSLIREQNGNIIYSNKIDTRTCLNILDVLDKYDIY
                     YQCNSIDSMLSKKIEGREDRLSVFLGSETEVIVKDDLREEIFKKDILKFVIIEEKNPS
                     ILDEIRKELRKVQGIKITSSWPNNIEVMNEGVDKGNAVKILAEKMNIDREDIIAFGDN
                     YNDIEMIKFAGLGVAMGNAEELIKQEADYVTDTNQDSGVAKAIYKFLELKESLSS"
     misc_binding    16873..17084
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            17171..18487
                     /gene="argH"
                     /locus_tag="PC466_001376"
     CDS             17171..18487
                     /gene="argH"
                     /locus_tag="PC466_001376"
                     /EC_number="4.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012101354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HDF2768767.1"
                     /translation="MKLWGGRFRKAENQLMEEFNKSFGYDCVLYKKDIEGSVAHVHMQ
                     VKCGLLTEEEGKSITEGLKGILEDVENGKLVLDGEYEDIHSFTEINLIQRIGDVGKKL
                     HTARSRNDQVAVDMRLYAKEKANDLVGLISEFKATIKDVADKNPVMMPGYTHLQRAQV
                     VTFKHHLMAYYSMFDRDEKRIKNAIEILDESPLGCGALAGTTHDIDRSITCEQLGFKK
                     VVDNFMDGVSDRDYLLELMSDFSIIMMHLSRLSEELILWSSQEFGFVEIDDLYTTGSS
                     IMPQKKNPDGAELIRGKTGRVYGNLFGLFTVMKGIPLAYNKDMQEDKEGFFDSVHTLE
                     MCIQIMDRMIATLKVNEDKMKQAVKNGFLNATEVADYLVKNNVAFRDAHGIVGSIVIY
                     CEDNKKAIEDLTLEELHKFSDAFKEDIYDFIDYESILNKGIKKNLK"
     gene            18736..19074
                     /locus_tag="PC466_001377"
     CDS             18736..19074
                     /locus_tag="PC466_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2325 domain-containing protein"
                     /protein_id="HDF2768768.1"
                     /translation="MNLLVIGGHERMEKDYMVMAKKKGYKTKVYTTMSSKLNNSIGRP
                     DAVVILTSTVSHKMSRTVESQAKKQDILIVRHKNSSKVAFNECLDMVDECLGNCSKCK
                     LKDKQKQKNI"
     gene            complement(19201..20490)
                     /locus_tag="PC466_001378"
     CDS             complement(19201..20490)
                     /locus_tag="PC466_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HDF2768769.1"
                     /translation="MKRNLSLLLICLLIFTSFLGSSNISFADNEPAIVAKHAVLMDYE
                     SGKILYNKDGNSKLYPASTTKVWTACLVLKEVKDLNQVIEIKDLPQIDGSSMYLKNGE
                     SFTVKQLLDALLVHSANDAAFVLARYVGGGNVQKFIDLMNSEAKKIGATNTHFNNPHG
                     LPDPNHYTTAHDMALIAREAMNNDTFRQIVKTKSLKFEATKAYPYERYFVNTNKFLTS
                     HDKITYKGQPINIKYDIVDGIKTGYTDAAGKCLLSSAVKDGRRVIVAVFNSTNADLYL
                     DSRILIDYGFDNFKCATIVDKEKYTDTKKVLFTKQHELIYEPKNSYRIFLEKDESQGN
                     YDTKTELNKIDLPIKKGAKVGTLNVYNNGKLENSIDLIAKNNLDSSLPFFTGNNILMT
                     FVKIIAGILVLLVLFIIASNIKKKKRKKARSKKNMKK"
     gene            20570..21274
                     /locus_tag="PC466_001379"
     CDS             20570..21274
                     /locus_tag="PC466_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComEA"
                     /protein_id="HDF2768770.1"
                     /translation="MKKKVKFISFFVLFILIISSIIVYKSLIFKDDIYVVSKKNLPNE
                     KTHVVENEIKGEDNNHNKVTKDIDKNFQNNKITIYISGAVNRPGIVTIESDKRLYDAV
                     ELLGGTTKEADLNGVNLSVRLEDEQHYIIPKIGEATSVTSNDDSNKPNQKNESRGEPK
                     NKSNKNISNESKVNINVATIEELDSLPGVGEATANKILQHREENGQFSSIEEIKNVNG
                     IGDKKYENIKDLICVD"
     gene            21366..22412
                     /gene="selD"
                     /locus_tag="PC466_001380"
     CDS             21366..22412
                     /gene="selD"
                     /locus_tag="PC466_001380"
                     /EC_number="2.7.9.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015617929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:21414..21416,aa:Sec)
                     /transl_table=11
                     /product="selenide, water dikinase SelD"
                     /protein_id="HDF2768771.1"
                     /translation="MKKEQKKLTEMTTAGGUAAKIGPEVLASVLSQLPKNDNIENLLV
                     GLDTADDAAVYKLNDDMALIQTLDFFTPMVDNPYVFGQIAASNSLSDVYAMGGKPLVA
                     MNIVCFPSCHDMDVLAEILKGGFDKVKESGALLVGGHTVDDKEPKYGLSVSGIVSPNK
                     VLSNATAKPGDKLIITKPIGVGVLNTAMKEGMVEQHIADKVIEIMIHLNKYAAMSFEK
                     FDVNSVTDITGFGLLGHTLEMAKASEVSIEIESKHVPIIEGAIEMAQMGIIPAGMYKN
                     MHYVSKDVEVVGNIEVAVQDILYDPQTSGGLLISVKEELAEELVKDMKLNGAIEAKII
                     GSVVPKGEKYITVL"
     gene            22430..23842
                     /locus_tag="PC466_001381"
     CDS             22430..23842
                     /locus_tag="PC466_001381"
                     /EC_number="2.9.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-seryl-tRNA(Sec) selenium transferase"
                     /protein_id="HDF2768772.1"
                     /translation="MIVLSKRELFAMLPSVDEVLSDNRIVEIINEYPRSLVLESVREV
                     IDLKRQFILRLKEDASNSVTIEFGEIIESAIERVKLNYSLSLKKVINATGTVIHTNLG
                     RSLLSEDIKDELWCAASRYSNLEYDLDNGERGSRYSHLTSTIKRLTGAEDVLVVNNNA
                     AAVLLVLSTMAKGGEAIVSRGELVEVGGSFRIPSIMALSGAELVEVGSTNKTHLKDYK
                     EAITEDTNVLMKVHTSNYRIMGFTESVSIEELVNLGKKYKLPVIEDLGSGVFIDLSKY
                     GLSYEPTVLDSIRQGADVVTFSGDKMLGGPQAGIIVGKKEYIEKMKKNQLTRALRVDK
                     LTICALEATLRMYLDETKAIENIPTLKMLTYKIEELEVKANKLFEKITALNLNANINI
                     EDGFSQVGGGSMPLETISTKVISITPEHMNVSSLEKKLRLSEAHIIARVYDNKYVLDV
                     RTIFDDEFDVIVAELRKAFN"
     gene            23956..25839
                     /gene="selB"
                     /locus_tag="PC466_001382"
     CDS             23956..25839
                     /gene="selB"
                     /locus_tag="PC466_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenocysteine-specific translation elongation
                     factor"
                     /protein_id="HDF2768773.1"
                     /translation="MKNVVIGTAGHIDHGKTTLIKALTGRETDTLDEEKKRGISINLG
                     FTYFDLPNNRRAGIVDVPGHEKFIKNMLAGASGIDIVLLVVAADEGVMPQTVEHLDIL
                     SFLNIKNGIVVLTKSDTVDDEFRELVKEDICEKIKGTFLEDAEIIEVDSISKRGIDTL
                     IEKIDKMSDDIEDKNENSPARLNIDRVFSIKGFGTVITGTLIEGKISIEDDLVIYPQV
                     LKTKIRSIQVHGENKDTAYAGQRTAINISNVKVDDIKRGDVLAAPNSLEESMMLDVKL
                     SLVNHLDKGLKHWDRLRLYHGTREILCRAVPLDKELIESGESGYVQLRLEESIVSKKG
                     DTFVVRRYSPMETIGGGVIIDPSPKKHKKFDEKVIEALKIKEKGELKDIIEEYLKRNL
                     KNYPNIKEIMSYSGAHEEDVKRALEALISEDKVFIIGNMYMHINQYNKLKENTIKLLS
                     EYHKKYRLRKGILKEEVRSKIESNFKTREMDILLEKLSTENAIKIENNIVSLLDFEVI
                     LNDKQKEIAKKIEKRLKSCGVSSILTIDEVSEGNHNYAEVLESMIGNKVEKLDDLYIM
                     DKDIYENAKNILINYIKENKEITLGEYRDLIDSSRKNCMIILENFDRNKITKRVENKR
                     ILF"
     gene            25944..28682
                     /locus_tag="PC466_001383"
     CDS             25944..28682
                     /locus_tag="PC466_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation-associated two-component system
                     sensor histidine kinase"
                     /protein_id="HDF2768774.1"
                     /translation="MKNIIPDVKPDIKEREDMSLLFIIMGSVLLLFIIKDIEKYETLL
                     HAIYTIFLVATGVIIFNTTKFKVDSFSTFLGLIFIATGVLECIYLFNSLGIKTKSIME
                     INITISAITDLFPILGVYLSFKFVKDNKQIYSSIILFIATATLTITSLFIISGICDYL
                     GNGKSQYALGVIISIFIIIISIISGIELNSSSNKGKWEYDEKKIFNRIIVIIILSRVP
                     NLLHIVIDNRNVERILSQIIINVALYYLYNYIVSKNIKKTALELHDTNEELTKKTESL
                     KEKNKKLIYETEKIEELKGILMKRESRLQSTLDVAVNSIVVFSKDGEITYANKSFRNT
                     FGDYKEQDKLTDKIKNFNDLIESIHYVFVHEKNAEKLISTSDNKVYQAIFAPLIIASQ
                     TEGVLCVLEDKTKKKEYERKLIEANKRSKDFLESIGDGIVVLEGNNKIYVNNACREIF
                     KNNLESIDFSLVCKSEESIEKRYVIDGEVKYVEMSFSQYTNAGTNKTIIVIRDTTSRK
                     ISQIKLEESQSSYSRFIDILPDGICLLKEDLSINYANKSFLDMLAFTNIDDIKDSNIK
                     LLMNANTEEKMKFTDNMAKVLNENRSILLLEYELINSYDDIVEVELSALPFAIYNTRY
                     IMLIIKDLVHKKYSEQAEKELLERFKTDKIKTEFFANMSHELKTPLNVISSSNQLVDS
                     FYRNEKIKDYNNNIKSHVDLVRQSSYRLQRLINNIIDLTKMESGFYTLKLAKYNIVSV
                     IEDLFMNIEEYALRKDIKILFDTDLEEINVYIDKVEIERIMLNLLSNCIKFTDNGGWI
                     YVSIHYKIDKVIISVKDTGVGIPQDKLELIFEEFSQVDKTLSRNTEGSGIGLAIVKNL
                     VSLHGGDIEVVSEVNKGTEFLISLPMKGFSSEHYTEDKRIYNIQEKIKIEFSDIYY"
     gene            complement(28801..29745)
                     /gene="manA"
                     /locus_tag="PC466_001384"
     CDS             complement(28801..29745)
                     /gene="manA"
                     /locus_tag="PC466_001384"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HDF2768775.1"
                     /translation="MEPLFLKPIFMDRIWGGTALKDKFNYEIDSPTTGECWAISSHKN
                     GDCLIENGKYKGKKLSELWNKNRELFGNTPGDKFPLLTKILDANDNLSVQVHPNDEYA
                     KKNENGELGKTECWYVIDCSDDAEIIIGHNAKSHKEFVNMVNNNEWDKLLRKVNIKKG
                     DFFYVPSGTIHAICKGTLILETQQNSDTTYRVYDYDRTDNSGNKRELHVQKSIDVTNV
                     PHINFDTDYKIVSTSDFKCTTFVSNEFFSVYKLDVFGKCNFTHNTPFSLYSVLDGNGK
                     LIHNSVEYNLKKGMHFILPNDFGDFSFEGNLEIICSHI"
     gene            29918..31279
                     /locus_tag="PC466_001385"
     CDS             29918..31279
                     /locus_tag="PC466_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HDF2768776.1"
                     /translation="MELFKAESKKYEKEFLKLLEQWVSIPSFYDRKTVSKDMPFGKGV
                     YDALNWFENLGRENNFKVKNIDNHAVQIEYGNGKEYVDIFGHCDVVNPGEGWDSEPFK
                     LNIIGDKLVARGVSDNKGPMIVNFLALKMIKDLDINLKRKVRLIAGGNEESGFKCIKH
                     YYSKEPYGVCGFTPDAKFPVLNGEKGGAIIKLISNIDDKSLYISGGIEFNTIPDKVYI
                     KNVEKLGKDNICFDINNISINYDNGNYIVYGKGGHSSKPEKSINPILATIKLLSENID
                     EKWTKDLYKLINQDNINGNLFGLNIEGKCGILSIVPTIINIVDGKLEVVLSVRYPEIL
                     TIEDIIKKFNLYMEQNNINKFELIGENLKQANYIDRNSKLVRSLHDIYIKYSGDLKND
                     VRVTSAGSYASEMNNSVIFGCEFPDGSFGNVHSANEFASLDRFITAIGIYAEAIITLC
                     NKI"
     gene            31367..33256
                     /locus_tag="PC466_001386"
     CDS             31367..33256
                     /locus_tag="PC466_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDF2768777.1"
                     /translation="MITKKHAIIVKSLSNKDGYMTSNELAIKLDVSTKTIKRYIADLN
                     SVLSKYDLVIASSRGIGYKLSGSKNNIARAVKEANKYIDGFLDDSEESRMSNIICMLI
                     NRNYMSIEAMAEELNLSIAAINKLSSKLKRKLEKYDLVIKSKPYYGSYIHGEEINIRQ
                     LITDYAIKLDEKSKVKVFLDDISENDIYCIESILEKHLREKDTIISDKDFNLLLSKII
                     VSVFRSKRGHSNNINLMDTSYRFHNYYFIENLMKEISDKIGFKLIEDEVIYISNYSGV
                     IAYKGTQGRKNTSEIEERISSVISSALQDIFLISGSDYTKDDEFMVAISDHIKRFLNR
                     ARANVKSNNPLLHQIKEKFPIAFNLAVFLSNKLETEFNLKLDEDELGYIAIHFAASNE
                     RMKKNTSKKICIVCHYGIGTGQLISEKLKQNISDLSVVGVYPVRYLDMAISQDVDLIV
                     STVELKGYEKPVLYIENIFDDSLIENVNKAFYEKEERRKIISNMFDEKAFFSIKASTK
                     EEVIISLSNKLKERDFIEESSIKSIIDRENISSTEIGNLVAIPHTIVKGDKKSIIGVG
                     ILENPIIWDKQEVQLVFMVFFNTKEKHNFSIFKYLYNFIKDEGGVRGIIKICDFNKLM
                     ALIGN"
     gene            33271..33726
                     /locus_tag="PC466_001387"
     CDS             33271..33726
                     /locus_tag="PC466_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2768778.1"
                     /translation="MGTNIFNKEYVFLNVDAKSKVEVLKFISKKAKDLNLAEDESLVY
                     EGLMAREEQFTTNLGESIAIPHTKNDAIENPAVVVLKFNEDVVWNEGEDKVKLAISLL
                     MPGKSKENIHLKLLSSLSRKLINKEFKDSLLKSDNVEEISNLINEALGL"
     gene            33785..34102
                     /locus_tag="PC466_001388"
     CDS             33785..34102
                     /locus_tag="PC466_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HDF2768779.1"
                     /translation="MNKKLVALCACPMGLAHTFMAAEAIEQAAKALGYEAKVETQGAD
                     GVQNELTRDDILGATMIIHAVAITPEGMERFDGCEVYEVELQEAIKNAEGVIKEIEED
                     LGI"
     gene            34127..35389
                     /locus_tag="PC466_001389"
     CDS             34127..35389
                     /locus_tag="PC466_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HDF2768780.1"
                     /translation="MAIKKKVINSSGASTTGGNNVGKSTPSSPTQSKGNGKWKEISKH
                     IMTGISYMIPVLVMGGLIGALSQLIPYAILGLDPSVGIVDAMNSGEFTGFKLSLLNIA
                     QLMSNFGFTLFGFAIPLFAAFCANSIGGKTALIAGFIGGYIANKPVGVPQFIDGQWTE
                     VVPVASGFLGAILIAFIIGYFVKWLNKSIKVSHNWLAFKTTFLIPLIASLACMVLMIF
                     IITPFGGLINESMKNFLTAAGAAGEYVYATALAAATAFDLGGPINKAAGFVALGLTTE
                     NVLPITARTIAIVVPPIGLGLTTLLDKRLVGRRVYDRQFYQAGKTSIFLSFMGISEGA
                     IPFALERPGFVIPLNIVGSVIGAITGIILGAIQWFPESAIWAWPLVDNLFGYIIGIAV
                     GAIFIAVGNIFYRNKLIKDGKLVVDYID"
     gene            35494..36558
                     /locus_tag="PC466_001390"
     CDS             35494..36558
                     /locus_tag="PC466_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HDF2768781.1"
                     /translation="MDKIEKVREYFREYDIDGFLINSPTNKFYVGNLFSSSGYVFITK
                     ESQYIIVDFRYFEEIKRKSSLFNVVLMDKTRTHFDIINDICREQNIKEIGFEGNEVSF
                     DLYRSMSNKLSATLKSVDLSTLRETKNEDEIKYIKKACEIVDATFYHIVDFIKIGMTE
                     KQVENEIVRIIKDLGGQKESFDTIVASGLRGALPHGKASEKIIEYGDFVTFDFGAKYN
                     NYCSDITRTICMGTINKELEEIYNIVRKANEECIRVLRPGMTTGEIDKVARDIIGSYG
                     YANNFGHNLGHGVGIMVHEYPALAPESNEVLKEGMIVTIEPGIYVPSLGGVRIEDDVL
                     ITQDGCMRLTTSTKDLIVVS"
     gene            36612..37790
                     /locus_tag="PC466_001391"
     CDS             36612..37790
                     /locus_tag="PC466_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PatB family C-S lyase"
                     /protein_id="HDF2768782.1"
                     /translation="MYNFDDKPDRVSEKCRKWDLNIIRDKFGDIREDFVPMWIADMDF
                     KIPTEIENKFIEAVRRGVFGYTYCYDEFYDSVIGWQKNMHEVNVEKEWITLTYGTVST
                     LHYVVQAFCKKGDSIILNTPVYDPFESSAKKQGVNVICNTLDVVNDRYYINFDKLEVQ
                     IKENKPKLMMFCTPHNPSGRIWTIEEMTRVATICKENNVILVADEVHAEHIHYGKFNS
                     ILKIGKELLENVILLTSPNKGFNLGGLKTSYSIVINKNIRDKFRNKLKQNSITSPNVF
                     GIIGLITAYNECHEWLSGVNEYIKSNYELLETWVNKYNKIKLMKMESSYLAWMDISGL
                     GISASEFTDKLAIDTGVLLEDGSHFVKDGEKYVRINLGTQKENVIEALNRMDLFLKSL
                     "
     gene            complement(37981..39039)
                     /locus_tag="PC466_001392"
     CDS             complement(37981..39039)
                     /locus_tag="PC466_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HDF2768783.1"
                     /translation="MNKKKITFIFVILILALILFSFFRSSSQNTKYSKTSYYLGTVNE
                     VTIFNVKESKSDKILNECDSILRYIDNKMSTHIPGSDVSKINDNAGKKFVRVSDDTFF
                     VVKEAIQYSKLSDGYFDITIGPLSNLWAIGTDKAKVPSDSEIQKLLPLIDYKNIILDE
                     KNKSIKLTKENMKIDLGAIAKGYAADKIVAYLKSEDVKKGLVNLGGNIFTLEDGKNDK
                     PFKIGIQDPTSKNGESIGNIETTNKSVVTSGIYERFIEKDGKIYHHMLNPFTGYPFEN
                     NLSSVTIISDKSINCDALSTSTFGLGLEKGMDLINEIDNVDAIFITKDKKVYLTKGIK
                     DNFKLTDKSFSIEKLNKQ"
     gene            39106..39477
                     /locus_tag="PC466_001393"
     CDS             39106..39477
                     /locus_tag="PC466_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HDF2768784.1"
                     /translation="MKKKDILLILGILVVIIACYGIINVINSKNAGNIEIYVDNKLYK
                     TVSINAKEEFKIENRGGYNIVKIHDKGVEIVDASCPDKVCVHTGFINKPSQSIVCIPN
                     RVSIKINTNEKNDNQEDIISK"
     gene            39514..40188
                     /locus_tag="PC466_001394"
     CDS             39514..40188
                     /locus_tag="PC466_001394"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HDF2768785.1"
                     /translation="MVNLGNDWDELLKEEFEKDYYLNLRKFLIEEYKTRQIFPNMHNI
                     YEALKHTSYKDTKVLILGQDPYHGDNQAHGLAFSVQPQVKTPPSLLNMYKELKDDLGC
                     FIPNNGYLMPWADQGVLLLNTALTVRAHEANSHKNKGWEIFTDRVISILSEREDPVIF
                     VLWGSNARKKVELIDTSKHYILEAPHPSPLSASKGFFGCKHFSKINEILKKLGKEPIN
                     WQIENI"
     gene            40437..41276
                     /locus_tag="PC466_001395"
     CDS             40437..41276
                     /locus_tag="PC466_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HDF2768786.1"
                     /translation="MNFKKLSNAKVSVMAVVLSVGILSGYSALNKQVTLVVRGEERTI
                     STFSSNVGDLLESQNISYDANDIVTLDENTKLSNGDKIEVIDVKEKTVVETKDIPFEV
                     TVVEDGSLLKGDSKVKEEGKSGKSELIYKETYHNGKKVEKEFVKKVVKAEPVNKVVSK
                     GTKVEMQVASSRGESSRRMASSSSSSSSSNNGKNMRVVATAYTGHSITATGTKPKWGT
                     IAVDPKVIPYGTKVYIPQFDMVFTAEDCGGAIKGNKIDIYMNDSKTVYNWGRKTIDIR
                     ILK"
     gene            41519..41615
                     /locus_tag="PC466_001396"
     tRNA            41519..41615
                     /locus_tag="PC466_001396"
                     /product="tRNA-Sec"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:41553..41555,aa:Sec,seq:tca)
     gene            41766..42473
                     /locus_tag="PC466_001397"
     CDS             41766..42473
                     /locus_tag="PC466_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA threonylcarbamoyladenosine dehydratase"
                     /protein_id="HDF2768787.1"
                     /translation="MENNFTTRTSFLVGDDGIEKLNNSNIIVFGVGGVGSFTVEALAR
                     AGVGNITIVDFDDVDITNINRQIPALHSTVGRYKVDVMEERILDINPNINIKKIRSLY
                     NKDTSDEILTERYDYVVDAIDMVSSKIHLIETCEKKGLKIISSMGMGNKLDPTKIVVT
                     DIHKTSTCPLAKVMRKELRDRGIKKLKVVYSTEQPIELKKKVMNGRKVTPGSVSFVPS
                     VGGLIIASVIVNELLGQ"
     gene            complement(42615..43451)
                     /locus_tag="PC466_001398"
     CDS             complement(42615..43451)
                     /locus_tag="PC466_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF2768788.1"
                     /translation="MRNKIFLSILIIISLLIGCDKKSLLSIHIIDVGQGDSILVQTPT
                     NKNILIDGGDEDSENIIISYLRQKRIKTIDIIIATHPDSDHIGSLDNVIKKFNVNSIY
                     MPEQSTDSEAYQNLINSCTDKNLSIQHLYKNDVLNIDNNINIYVLSPSYIQEESNLNS
                     IVFKLTFNDNSFLFMGDAEEENEKEILHSFKLNNINFIKIGHHGSNSSSSLEFIKKIS
                     PDIAAISCGYKNQYGHPHREVINNLKQNHVSIYRTDRIGDIVFYSDGEIIFTKYNYEI
                     DT"
     gene            43639..44544
                     /locus_tag="PC466_001399"
     CDS             43639..44544
                     /locus_tag="PC466_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2156 domain-containing protein"
                     /protein_id="HDF2768789.1"
                     /translation="MFFKDIELNSKKELDPYFDLVDYEACEYCFSTLYMWQHVYKTGY
                     YIGEDFAVLVGEYEGDSFSILPLAKKDKLPEVVDFVLEYFSKNNKKIYLRGITTEVVE
                     FLKEKYPGRFEYIEERDLFDYIYDAESLRTLAGKKNQKKRNHINYFLKEYAGRYEAKL
                     LDKENFDECLVLMKEWESNKEENNEFDESMDDELIGIKKIFNHYDILKDKVKVFGVYV
                     DGKLEAFSIGELLNPNMALIHIEKANPDIRGLYPFINQQFLVSEFKDVEFVNREEDLG
                     IEGLRKAKLSYHPCRFVEKYSVREA"
     gene            44553..45737
                     /locus_tag="PC466_001400"
     CDS             44553..45737
                     /locus_tag="PC466_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2768790.1"
                     /translation="MEIRYAKEEEIESIKEIWSYCFNDTESFMKYYFNDKYKSENTVV
                     ALDEGKIISSLQLNQYKLLLNSKVYNTSYVVGVSTLPEGRGAGYMNKVMKFTLNELYK
                     KGQLVSILMPIDYRLYRRFGYEHCYDQIEYTINTDDLKNFKSSGKMIKSNLSQIDDLI
                     RIDRTFLNEVNGNVLKDEHYYENLFKEIQSEDGFLYIHEGNEKDGYIVYFLQEDKMFV
                     RELFYKNIDALKSMLKFIYNHNTQCKIVTISTPTIDKIRFILDNPKDSDIKIKPFMMG
                     RVINVKKFIEDIDIEKDINSSFNLLIEDKFIDENNGLFKISIQNKKVSVEQLDKKGAE
                     KPQEDFDIKLDINTLTQLSFSYIDVNEAIFLNDIKDVSEETLETLNCIFSKKNTYINE
                     YI"
     gene            45852..47153
                     /locus_tag="PC466_001401"
     CDS             45852..47153
                     /locus_tag="PC466_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEC/Rec2 family competence protein"
                     /protein_id="HDF2768791.1"
                     /translation="MGVIIIQIRRPLLIILMFVVAISFIITNNTKNDEELNDKIITIQ
                     GVVKGKIEKKRYNQYKVGVFLINDYTKNKNLKIGQKVNITGKFKSLDKMKYDDFDYGR
                     YIKSTGYKGIVYINNYKIIDKNKLYSLIGEIKFYISKTYRYLYKKNSDFINSILLAEV
                     ENLTEEQKEIFTRTGTSHVISISGLHTGILCVIISFLLRGINKLYKLLILSIFITLYC
                     IMVGASPSIIRSIAFVMIFYLSIFIDRKKDGISALSLIGIILIMNNPYVIYNVSFQLS
                     FLATLSILIFYNKINSIIKLSMVSLTISSNILTLPIIYYTFKGIPLLSIIGNLIIVPF
                     VGVIMYLSIASLIVFKVSVVIAKIISFFNSTLIESIFFLLEKISNLSFAYINIESPKF
                     YIVVIYYIGVFFYIFYIEGKEIKEQENELQGYYKECKREKL"
     gene            47107..48150
                     /gene="holA"
                     /locus_tag="PC466_001402"
     CDS             47107..48150
                     /gene="holA"
                     /locus_tag="PC466_001402"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HDF2768792.1"
                     /translation="MNYKDIIRNVKEKNFEKMYLFYGREYYLIENAIKAFKDSLNEGM
                     LDFNLDIIDGKEIVLNQLISSIETLPFMDDRKIVIIKDFELLKGKKKNFTDSDEKYLI
                     EHLDNIPDTTTIVFVVYGDVDKRKSLVKKIGNNGIVFDCDKLSDMDLFKWIKKSFALN
                     DVIIDNSQIMYFIEQEGYRDKSSEKTLSDLENEINKISSFVGKGNNVTNDVIDKLSQK
                     KVENDIFKLIDYIGEQNASNAMKILNDMIQEGESVLGIFSMIARQFKIIMQVRQLQLD
                     GYSTKLIADKLKMHQFVVGKALKQTKNFSDDIIVEILNYILESDYKIKTGLIRDTLAV
                     EMLVSRYCKREAI"
     gene            complement(48337..48603)
                     /gene="rpsT"
                     /locus_tag="PC466_001403"
     CDS             complement(48337..48603)
                     /gene="rpsT"
                     /locus_tag="PC466_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HDF2768793.1"
                     /translation="MANIKSAKKRISVIEKKTALNRVRKSQIKTAIRRFEDAVAAGNR
                     EDAVAKFQYAQKRIYQVASKGTIHKNAAARKVAKLAQKLNGMNA"
BASE COUNT        19156 a         5275 c         8345 g        16066 t
ORIGIN      
        1 gtatgcaatt gttgtatttt taggtttttt gtgattaatt aaaaaattat aaaaatcgtt
       61 tacatgttga tttttaaaaa aaaaagatat agaattatat agaaagtaat aaacaaaaat
      121 tggatttacg ggagtggaat gaaatgatga atgttacctt aacagatgtg aaagaggcta
      181 gagagaccat taagaacata gtaaaaagaa ctgacttact tgaaagtgtt aaacttagcg
      241 aaaaaacagg agcaaatgtg ttctataaat gtgagaatct tcaaaaaaca ggttctttta
      301 aattaagagg agcttgtaac aaaatagcga gtttaacaga tgaagaaaag gcaaatggag
      361 ttatagcttc aagtgcaggg aatcatgctc aaggagttgc attgggagca aaaatgactg
      421 gtataaaatc tacaatagta atgccagcaa ctgcgccttt agcaaaagtt agtgcaacta
      481 aaggttatgg agcagaagta gttttaaatg gtgcggttta tgatgatgca tatgcaaaag
      541 ctgttgaaat acaaaaagaa acaggagcaa ctttcttaca tccattcaat gataagtatg
      601 ttatagcagg acaaggaact atatctcttg aaattttcga acaattagac aataaagttg
      661 atactatact atgcccagtt ggtggaggag gaatcatctc tggtgttgct gttgcagcaa
      721 aagcattaaa tcctaatgta aaaatagtcg gtgttcaaac tgcaaatata ccttcaatga
      781 aagagtcaat aaaaaatgga aaagtaacaa cagcatttaa tgatactaca atagctgatg
      841 gtatagctgt taaaactcca ggagatttaa cttttgaaat aataaatgaa ttggttgatg
      901 aaatagtagt ggttgaagag acagaaattg cagaatcaat attatttatg atggaaagtc
      961 aaaaaatagt ttcagaaggt gctggtgctg tatgtacagc tgctatatta agtggtaagt
     1021 atgtaccagc aaaagatgaa aatgtagttt gtataatatc tggtggtaat atagacataa
     1081 atacgttata tagaataata ggtgttgctt tagctaaaga aggaagaaga tattcattta
     1141 gtacaattat ggaagataag ccaggaaact ttgctgagtt aactagaata ataagtgaga
     1201 atggtggaaa cattttaagt gctaatcaag gtaaattatc agcaggggaa gctctaggaa
     1261 aacaaagtgc ggaatttata ttagagacaa tagattatga ccatatagct agaataaaga
     1321 aagctataga agaaaaaggt tttaaaatta tagaattata ataaaaagtg tatataatat
     1381 acaagaaaaa tagtataata gtgtatgaag atacatttta tgtgtattag attaacgaat
     1441 taggaggatt ttaaaatgaa acatgaagta atacatacta atgatgcacc agcagcttta
     1501 ggaccatatt ctcaagctat aaaagctgga aacttattat ttgtatctgg acaagttcct
     1561 cttgtaccag agactatgga agtagttgaa ggagatgtac aagctcaaac tgctcaatct
     1621 ttaaaaaatc ttaaagctat attagctgaa agtggagctg atttttcaaa tgtagttaag
     1681 actacagtat ttataaaaga tatgaatgaa tttggggcta taaacgaagt ttatgctgaa
     1741 tattttggag aaaataaacc agcaagagct tgtgtagaag ttgctagatt accaaaagac
     1801 gttaaagttg aaatagaagt aatagctgta ttataaaaat acaatatttt taatttgaaa
     1861 aggctgaaaa actatattct agtgattcag tctttttata aaaaaataaa tcacaataaa
     1921 gaacatgata aatattgtcg aattaaaaaa taaaattaaa ataaatattg caatattttt
     1981 gagaaggttt tataatgagt atataatttg aaacgtgtaa ctattaaatt aggcatgagt
     2041 tcttggatat ttttatcctg aggattcatg ccttttttgt attgaaattc aaaaatctat
     2101 ttaataagga ggaagtattg tgttaaattt tttcaagaaa aataaaagct ataagttaca
     2161 tgcagtagtg agtggtaaca gcattaatat tgagaaagta aacgattctg tgttttcaaa
     2221 aaagttaatg ggagatggag ttgcaattat tcctaatagt aatgttgttg tagccccttg
     2281 taatggtaaa gtaactgtgc ttacagaatc aaagcatgcc tttggtatgg tctcagatga
     2341 gggtgttgaa atattagtcc acataggaat tgatacagtt aatttacagg gtgaggggtt
     2401 taaaaatgaa gtgtctcaag gagatactgt taaaaaaggt agtccaataa taagttttga
     2461 aagagaaaaa ataaattctc agggaattga ttgtacaaca ataataattg tattaaatca
     2521 tagcgaattt tcagaaataa attgcatggt agaaaatgaa gttgttgcag ggcaagatac
     2581 tgttattgaa attatgaaat aataggaagg gattaattca atatgagagt agtaaaaatc
     2641 tttaataata atgcattatc tacagtaact aatgatagga aagaagctat tttactaggt
     2701 cttggtatag gttttaataa acgtccagga gataaagtta atgaagataa aatagaaaag
     2761 atttattatg ttcaagacca catgcaaaca aaatttttag aattattaaa aaatgttagt
     2821 ccagaagtga tggatgcttc acaacaaatt ataagtctta taccaggaaa tgagggaaaa
     2881 tttaataata aagggatatt atctttagtg gaacatatta gttttgcaat agatagaatg
     2941 aaaaataatg tttttttacc taatttaatg cttttggata taaagatgat gtattcaaaa
     3001 gagtttgaat taggagtaaa agctttagaa attatatata gagtatgtca tatccatttg
     3061 cctgaagatg aagcaggtta catagcttta cattttgtca atttacaatc aaatgataat
     3121 ttggcatatg atactttaaa atttgtaaaa ggtagtattg atttgattaa agaatgttat
     3181 ggattagaat tagacgaatc gagtttaagt acattacgtt ttagaactca tcttaaattt
     3241 cttgctcaaa gaatttttaa gaatgaaatt tgtcaggatg ataaaatgat tgaaatgtat
     3301 gattatttaa ttaacaatca tcctaaaaat aaagaatatt tagaaaagtt aaatgtatat
     3361 attgaaaagg agtttaggta taaattagat aaacctgaaa aaatttatct actactacac
     3421 ctaacaaaaa tcttataaga atgagatgaa ttagtaatag aaatatataa ttttaggggg
     3481 ggataagatt gaaagaaaaa ctacttggag gactggaaac atttgcaaag gcaatggttc
     3541 agccattaat gtatttatcg agtgcaggaa tattaatggt ggtaggtgta ctacttacaa
     3601 atgatatgtt attaggagta cttccatttt ttaaatggga gccaattcaa atatttggaa
     3661 gcctaattta taactgtata atggctatta ttaataatct tgctgttata tttgctatag
     3721 gtattcctgc tgcactagca aaaaaagaga agcacaaagc agcgttaata ggatttatga
     3781 gttatataat ataccttaca gcttccaaca ctatgttaac atcactaggt caactagcaa
     3841 aagaaagcaa gatgcttgga ctgataggga ctggacaagc tactatttta ggtattcaag
     3901 ttgtagatac aagtgtattt ggtggaatta ttttagggtg tatagctgga tatgtattta
     3961 atcgtacaag caacaaaaca tttaaaggag ctttacagat atactcggga gcaaatttta
     4021 gttttatatg catgttcttt gtatccattt taattggagt tgtgagtaac tttatatggc
     4081 cattagctca acaaggaata gcttctcttg caaatgtcat caaagataca ggtacatttg
     4141 gtttattctt atatggtttt ttagagagaa tattagtacc aactggactt catcatttaa
     4201 tctatacacc atttcagttt tctgatttag gaggagtgct taaagttggt gcagatacag
     4261 tttcaggagc ctatgctata gttatgacag aaatgaattt accagttgag cgtttctcag
     4321 atagtatata ctacatggca actggattta caaagatgtt tggttatata ggtataggag
     4381 ctgcctttat ttatactgca tataagcaaa ataagaagaa agttaaggca acgattattc
     4441 cactaataat tacggcagta ttagcctctg taacagaacc attagacttt atgtttgtat
     4501 tctgtgcacc acttttattc tttgtacatg cagttatagc tggtcttttt atagctttat
     4561 taaaaatatt tgatgttact gcattatgtg gagggaactt attagtatca attataatga
     4621 atactacagt aggtgtagaa aaaacacact ggccagtaat gatgatatta ggacttgcac
     4681 aaattattgt atattttgta gtatttagtt ttttaattaa gaaatttaat tataaaactc
     4741 caggtcgtga agatgagagt acagctacag gcgaagaaca atcaaaacaa cttaatttag
     4801 atgcaggtat agaaaatata attgatgggt taggcggaaa agaaaatatt aatacagtag
     4861 aaaattgcat cactagatta cgtgttaatg taaaagatga aagtaagatt aatgaagata
     4921 taattaattt aacgccaaat agcgggattg taaggaaagg aaaagatata caaataattt
     4981 ttggacttca tgtgcatgag gtaagacgtg cagtagaaga ttttttagaa gcttattaaa
     5041 gatatatatt tatatagcaa gggtaaataa cagctttaag tgctgtttac tatttattaa
     5101 agatacatat aatttataga ggaggaataa ttattatgat tattactatt gttggtggag
     5161 gaagcacatt tactccaggt attgttaagt caattgcgtt aagagaaaaa gagttagagc
     5221 ttgaggaaat tcgcttattt gacattgata aagaacgcca agataaagta gctgtagttg
     5281 tcaactggat actaaaagaa gatgttaaaa cagatgttaa actaactgta actaattgtg
     5341 aaaaagaagc gtatacagat gctacattta tatttgcaca aatgcgtgtt ggtaaatatg
     5401 aaatgcgtga gcaggatgaa aaaattccat tgaaatatgg ttgtgtaggt caagaaactt
     5461 gtggttgtgg agggatggca tacggactgc gtacaataca accaatgata aaggttattg
     5521 atgatgtaga gaaatatgct aaaaaagatt attggatatt aaattactct aatcctgctg
     5581 caatcgtttc tgaagcttgt cgtaagttaa gaccaaatgc aaggattata aatatctgtg
     5641 atatgccaat agctattata gatatgatag cggagtcatt aaatatcaat gacgttcata
     5701 atatacgcta tgattatttt ggtctaaatc attttggctg gtttacttca atagattata
     5761 aacatagaga cttaatggaa gagattaagg aatacataaa agaaaataaa atattattac
     5821 caaaatctta tatagaaaac ttaaataaaa gtcgtagtac aggaaatcgc catgctgtaa
     5881 gtagctggat acatgtttgg gaatctgttt atacaatgtt agaaagcttc ccaaaatatc
     5941 tgccaaacac ttatttaaca tactatcttt taagtaaaga aacagtggaa cattcaaaca
     6001 taaatcgtac tcgtgcaaat gaggttatgg aaagccgtga aaaagactta tttgaaggtg
     6061 tgagacatta cttagaaact ggagaaattt ctgaaaaagt attttatgca ggttcacatg
     6121 gagattggat tagtgatttg gcagtttcaa ttaaaaatga tacacgtagt cgttttttag
     6181 ttataactga aaatcgtgga gctataccaa acatgccata tgatgcaatg gtagaaattc
     6241 cagcatatat tggtaaagat ggtccagaag ttattgctcg aggtccaata cctctattcc
     6301 aacaaggatt aatgatgcaa caacttaaca gtgaaaaatt gatagtagaa gcttatatag
     6361 aaaatagtta tgaaaaagct ttacaagcat tcacattaaa taaaactatt ccaagtatga
     6421 atgttgctaa agaaattttg gatgaaatga tagaagttaa taaggaatac tggccagaat
     6481 taagatagta ggataaaaga aagggttttt atttaataat tagatatgtt ttcagagtct
     6541 tttatcaaaa tgtattcaca aacatatggc aatatattaa aataaagagt gatattttta
     6601 gaagaatggg gtgatgcaat gaacattata aataaaattt tttggcaaga agataggatt
     6661 ggcatgatta caaataattt agaggcagat acacatagcc actgcatgtt acaactgttc
     6721 ttagggatag aagacagcat tgaaataaca gtcaatgaaa aattagttaa atgtaattgt
     6781 atcatagtag ataaaaatat ctctcattca ttttcagcaa gaaaaaaagt ttattactct
     6841 gctattattg aacctacatc tatatatgca gaacagctta cctcaaaaat gaatgatttt
     6901 ggctactgga tatgtgacaa tgatggatta gagaaattac gtcaacaagg aacttttttg
     6961 atatataact ctagtaaaga acaatattta agatttatgg aaatgcttaa taactatttg
     7021 aatataccta taactctcaa acattatgat gacagaatta ctgaattgct caatttatta
     7081 cgtacttgta attgtgataa tcatactatt tcaagttttg cagataaagt gtccctatca
     7141 gcaagtagat tatcacatct gtttaaagaa caaataggga tacctttaaa aagctatatc
     7201 ttatttcatc aaatggagtg tgcttttaga gaattacttt ctgggaaaaa tgttaccgaa
     7261 gcttctatga ctgctggatt cgatactcca tcacactttg cagggacagt taagcgaatg
     7321 atgggaatgc ctgtttcttt atctttgaaa gatagcgaat ttttgaaagt atattaaata
     7381 ttctcgttat ataatgaagt tgtactaaga aaggggcttt gttatgaata aagaatattt
     7441 agaggaaaca aaaatgttaa attataatga accacaactt aagcttttgg tatcatcaaa
     7501 gaattggttg gaattagatg attttcataa aataaaatct atttatgagt ttgtacagaa
     7561 tgatatttta tttggatata atgcttctga tatgttaagc gcaacacagg tattaaatga
     7621 tggtatggga caatgcaata caaaagctac tcttttaatg gcattattac gtgcagtgaa
     7681 tatcccttgt aggcttcatg cttttgatgt aacaaaagat tttcaacgag gtgctacatc
     7741 caaattgatt tcactattag caccaaaata tattcttcat acttgggtag aggtatttta
     7801 tcaagatagg tggattgctc tggagggtgt cataactgat aaaaaatatt tagaagcaat
     7861 tcagaagaag ttttttaatc atggtggaac gtttaaaaag tatgcaatag ctacaaatga
     7921 tttgaaaaat acatctattg attgggatgg taaagatact tttatccaaa aagaagctat
     7981 cgtgtatgat tatggtattt ttccatcacc agatgtattt ttttctactc attcacaaca
     8041 tatgtcaaaa ttaaaaaatt tcatatatgt acatcttatc agaaaaataa tgacaaaaaa
     8101 tgtatgtaag gctagaaaca attatattga taaaaacgaa tgagtgttta agaggtaact
     8161 atataggaaa tatatagaat aattaaaact gtactggtta aaatgaataa aaaggagtta
     8221 tcatagagca aacttaaatt gttcatagga taactccttt tctgtattaa cttctaataa
     8281 tttgatgtct ttttataaaa catatagata caattaaacc agtaaatgca agagtagctg
     8341 ctattgaaaa tgcaacatct attccatgaa tgttagacag catgtttgaa ctcatatgag
     8401 ctttcttagt agcacttgtc attatagtaa taagtatagc agaacctata gctccagata
     8461 tctgacggag tgtgttatta attgctgtgg catgagatat aagttctcta tctaatgttt
     8521 taattcccca tgtagttaat ggcattaaaa ccattgaaat accaatcata cgaatacaat
     8581 acatcaatga cacatgaatt aaagatgtat ctctgcctaa aaaagcgaag gataaagttc
     8641 ctaaaaacaa acatcctgtt cctaatattg atagagcatg aggtccatat ttatctaaat
     8701 gacgtcctgc aattggattg agtacaacca tcaatatagc accaggtaac attaatgaac
     8761 ctgaagataa tgcagaaaat cctcttacag attgaacgta cagaggaatc attaatgtag
     8821 cagacatcat tgaggcatat acaatcataa ttaatattgt agaaataaga aatggtttat
     8881 ttttaaaaac cctcaattct aaaaaaggtt ctttagattt taattgacgc aatgtaaata
     8941 aaattaatga cataattcct attaatattg gtaaatatgt ggcaatatta gtccacccat
     9001 aattaccttg attagtaaat ccaattaata aaccaccaaa acctagagat gatagtacta
     9061 ttgaaggtat atctaacttt agtttttgag tttccccaac atttcttaat agaataaatg
     9121 atagtataac atctaatata gcaatagggg aaagaaacag aaataaacta tgccaaccaa
     9181 atgaatctac taaccatcct gataaagttg gacctattgc tggagcaaat cctactgtaa
     9241 taccaactaa actcatagct gcaccacgtt tttcctcagg gcataaatag agtataataa
     9301 cttgtaaaag tggcattaga gaaccagaac ccattgcctg caacacacga gcaatcaaca
     9361 tagttgaaaa attattagaa aaaagtgcaa taatacatcc tatagaaaag atagacattg
     9421 atgtaataaa taactttcta gtactaaatc gatttattaa ataagctgtt gtgggtacaa
     9481 taatacctgc aataagtaga taaattgttg ttaaccactg accaatatca gcagtaattt
     9541 taaaatctga cattatatta ggtaatgctg ttgacaatag tgtttgactg agagaactta
     9601 taaaagcacc agtcattaca attgctatta ttaaatttcc ttttttattg ttactttggg
     9661 tttccataat ttataacgtc tcctttttta attgattttt aatgctgttc aataaaagta
     9721 cttttggtct taaagtgtct tctttttcta aatatgcaat cattgcatcc ataattaaag
     9781 aatcatattg ttgatttttt ccctcgacgt ataatttttt tattgcttct agtaatttag
     9841 gattttcaag gagagaagta tcagttttga ttagttcttc tatatcttgt atcgttttaa
     9901 aaaatagcga tttattatga agggaaaagt aaacttcatc ttcttgttta tgtaaaaaca
     9961 ttgatttttc aattaaagga tttagattat ccatattttc tacaactaaa tctagaattt
    10021 gtatagtaaa tttggcaata aagtatacat ttatttctct tttttgtaca tgaataatgt
    10081 atataaactg atgaattaga gcatccaata agaaaactaa atcaaatata attttttcta
    10141 ttttatcacc atagttatca aataagctta atttgtattc attcaataag ttagctcgtg
    10201 attttgtttg caatttactt gtagccttac gttgctcttc agaaaaattt tctcttatat
    10261 aggtatttat ggtagttcta gaaaaaatat ttttccatac agcaattatc tttctgttta
    10321 acttttctga tgatggaatg tcattatttt cgtttatgga atgtataatt tctaaaaact
    10381 tttcatcata ataattgatt atttcgcaga taaaactttc cttagtttca aaatgcttgt
    10441 aaaaagtagc tttagacatt ttacactctt ttacaacatc cgatattgaa gtattttgaa
    10501 aacctttttg gtcaaaaatt ttttgtgcaa tatttataat gagcctttgt ttttctgtca
    10561 ctttattatc tcctttcacg caaaaacgtt tagtactata tagtacctac aagttttaat
    10621 aaatatatta tacatcattt ggaaaaaaaa tcaatatata gactgtaata tgaaattttt
    10681 gaaaaatttg ttgttatttt tagtcgtata aaaaagaaac ttaagagttt cttaagaatt
    10741 gtttaaagaa gttgcaataa attagtggta tgattatagt atgaaagaga atgtcttgaa
    10801 atttttctgt atcaaattcc aattatggag gtgtagtata tgaaaaagaa aatttgtgta
    10861 gcaataattt ttgctctatt tatagttttt gtagaaatgt ttattgatag ctctagcgaa
    10921 ggaagtaaaa ttatgacagc tgaattaagt aaatacagga aaggcgtaaa tgtattatca
    10981 ataaacaata ttatagtagc gaataaaaaa tatagtttgc ccaaagatta ttctcctcag
    11041 gaaagcagtg aagcgagaga tgctttttat aaaatgaata aagatgctca aaagtcagga
    11101 ttaaatttaa aagcttttag tacatataga agttatgaat atcaagatag attatttaaa
    11161 tcatatgtaa aagaacatgg agaaaaagaa gcaaatagat tttcagctaa acctggagag
    11221 agtgagcatc aaactggact tgcttttgat attggaggag atgaccagtc ttgttgggca
    11281 aataaaaagt tcaacaatac aaaagaagct aagtggttgt atgaaaatgc atataaatat
    11341 ggttttatac ttagatatcc agaaggtaaa gagaatataa caggatatat gtatgaatct
    11401 tggcactata gatatgttgg aactgaacat agcaaaaact ttgcaatgaa taatttgact
    11461 ttagaagaat atttacatat aaattaagag atggtttgtt aaaattaggt taaaataaaa
    11521 aataacctag actattagct gtgtaaagtg atataatgta aatacaattt aagataacta
    11581 ctcgaagggg agtagcttac acgaaagtgg taattaatcg tcaagacagt agaaatactc
    11641 ggttaattag caagggattc cttgatagca agaccttcaa aataagcatt aggtatgttt
    11701 gttttggggt ctttttttat tcaaggaatt tttatttaaa aaaatttaaa tttcaagtat
    11761 acataagagc ccccaaacat aaaataaatt tattgaagag gagggcaaca aatgtcttac
    11821 aaaagtactt atcaagaagt aattaaaaat ttagactcaa gtttatctgg tttgagtaaa
    11881 gaaagagcag aagagttgtt ggaaaaaaat ggagctaatg aattaaaaga agcagataag
    11941 gttcctactt ataagctttt cctagaaagt tttaaagacc cattagtaat aattctattg
    12001 atagctgctt tagtacaaat atttttaggt gaaacagtgg agtctataat aatttttgca
    12061 gttattatta taaactctgt tctgggtgtt gtacaaacaa aaaaagcaga aagttcatta
    12121 gaaagtttga aaaatttatc tgcaccaaac gcaaaggtaa taagagacaa taaaaaaatg
    12181 acaattccag caaaaaatct agtagttgga gatattgtat tcttagaagc tggcgattac
    12241 ataccagcag atggaaggct tatagaagca caatctctca aggttgtaga agggatgtta
    12301 actggagaat cagaaccagt tttaaagcat acagaaaaaa taagtgaaga tgtaagttta
    12361 ggtgaccaga aaaatatggt atttagtggt gctgtagttg tttatggtag aggttctttt
    12421 gtagtgactg gaacaggtat ggatactgag atgggtaaaa tagctgggct tttagaaagt
    12481 gctgaaaata aacttacacc attgcaacaa aaaatagagg attttagtaa aaaacttggt
    12541 gtaggtattg taatacttgc tcttttaata tttataattc aagtagcaag aaattacttt
    12601 atggctggaa atggagaaat gacacaaatt attttagatt cattcatgtt ctctgtagca
    12661 gtagcagtag cagctatacc agaagctcta tcatcaatag tcactatagt attggctgtt
    12721 ggaacaaata gtatggcaaa aaaacaagcc ataataagaa aattaccagc agtagaaact
    12781 ttaggttcaa caagtgtaat atgtactgat aaaacaggta ctcttacaca aaataaaatg
    12841 acagtagttg attattatat gtatggaact aataatgatg agttagataa agaaaaagta
    12901 aactattctt atcatgctaa attattgact atggtttcta cattgtgtaa tgactctcat
    12961 ataactagtg atggtaaaga agttggtgac ccaacagaag tggctttaat aaattattca
    13021 agtaaaaatg atttagatta tgataaatta agaagtaagt atatcagaat aaatgaaata
    13081 ccatttgatt cagacagaaa gcttatgtct actgtaaata gtatatatgg agattatata
    13141 atgtttacaa aaggtgctcc agatattgtg tttagtagat gtaaatatgc tttgaaaaat
    13201 ggttcaaaag tagatataac agatgagata atagaagaat ataaacataa aaatgaagag
    13261 ttttcaaata gagcacttag agtattagct tttgcaataa aagatgtccc agaagaagat
    13321 tttatacctt caattgatga cgaacatgac atgacattgg ttggaataat ggcaatgata
    13381 gacccaccaa gagaagaagt aatggatgca gtaaaagagg caaagagtgc tggtataaaa
    13441 actgttatga taactggtga ccataaaaca acagcagcag caattgcaaa agagattggt
    13501 ataatggaag aaggagactt ggctcttact ggaaaagagc ttgatgcttt gagtgaagaa
    13561 caactatatg aaaaactaga aaatataagt gtatatgcca gagtctcgcc agaaaataaa
    13621 attcgtatag taaaagcatg gcaacataag aataatataa cagcaatgac tggtgatggt
    13681 gttaatgatg cacctgcatt aaaacaagca gatataggaa ttggtatggg aagtggtact
    13741 gatgtagcaa aagatgcttc tgctatggta ttggttgatg ataactttgc aagtatagta
    13801 aatgctgttg aagttggtag aacagtatac agtaatataa taaaatcaat tacttatcta
    13861 tttgcaggaa acttaggagc tatagtatcc atagtatttg cagtgtttgc aggttggtca
    13921 aatccattta cagctttaca acttttgttt ataaacttag taaatgactc tttaccagca
    13981 attgcattag ggtttgaaaa gtcagaaaaa aatataatga ataaacctcc tagacacccg
    14041 gatgaaagta tactagcagg aggaacattg aaggcagttg ctataagagg ttgtataata
    14101 ggtgtagtta caataattgc acaatatata ggattacaag tatctccaga acttggagta
    14161 gcaatggcat tttcaacatt gatattagct agaataatgc aaacattacc tgcacgttct
    14221 aataatcaaa cagtaataaa attaggtttt ttcagcaata aatacgttat aggagcagtt
    14281 ttagtctgtc ttgggcttta ctctttaaca ctaataccag tgctaagagg aatattctct
    14341 ataccaacaa cgtttggatt gtaccagttg gggatttgcc tagggttagc attaatttca
    14401 tcaatattaa tggaacttaa caaattaata aatagaagtg aagtaaaata atcaaaaaat
    14461 taaagggcat attgatttta acaatatgcc ttttataaat agtctaattt attctatatt
    14521 atcgattatt tggaatgctt ttataacttc aggtaattct ttttcttcag gcattctaaa
    14581 tcttatgaaa tttttatcaa gtccagtaaa atcacttcca gatataactc ttatttttaa
    14641 tttagcaaac tcttgttgta aatctatgtc cttgttttta tgttcaactg tcataattga
    14701 tacagtatca ctagtttcag ctatattaag gtttttccat ggaattagta attgattttt
    14761 tatatctttt gttttttctt ttaattcttc tataaattga acatcatcta ataaatttgc
    14821 tgcaatacta cgagatattt cagacacttc gtaaggagta gaaatctttt taatagggct
    14881 aacaagttgt tctggaagaa ctgcatatcc tgctcttagt cctgctaaac caaatccttt
    14941 tgaaaatgtt tttaaagcaa ttacattatc ataattattt agaagcttga cagctgaatt
    15001 ttcttttggc atgtattcac cataagcttc atctaccata actgctatat catatttagc
    15061 tgcttccttt actatatttt caattgatga taaaggtata atttgtcctg taggattgtt
    15121 tggattgtct atgtaaatta ctttatattc tggatttatt ttttcaataa attctttttc
    15181 attaaacttg aaattatcct ctttctttaa aagaacataa tcataagttg caccatgcat
    15241 ttttatatct gtctcatatt ctgagaactg aggtgaatat cctaaaactt tatctccctt
    15301 ttcaataaat agtctattta aaaggtaaat aacatgtata gaaccatctg ccaaacaaat
    15361 tctgtcagta tctaatgcta taaaatcttt ccaataatcg actatattat cttttaaagc
    15421 aattgaatga ggatatcctc ttatcatatc aaattttaaa gcattaaaag cttctacagc
    15481 tttgcttgag taagacacgg tatttatacc ttcaccacag tctatctcga atacatcttc
    15541 tgaatgtcca gattctattg cataactttt tttcaactgc atttcaatag ctttgttaat
    15601 ttttagtttc atactttatc actccttatt tagtcaataa taaatgttat aaaagttgct
    15661 agatttaaaa tattatgaaa atatataata gtaaaaaatg aatataaata ttataatagc
    15721 tcactttatt taatatgatt atatatcata tattgtaaaa tttctagcat tataagacta
    15781 taaattgaaa atattcagaa aaatactaca agaaacgatt tattttgctc ttaaaataag
    15841 ttaaatgaat gttattaatt ttgtaaattg aaatagttta agtataaagt tatgatataa
    15901 tctaataagg gtaattcttt agattatatt aaggaaatat aggtatacaa taaaaagtta
    15961 tggagttgga ttatgggata taaattaatt gtaacagata tggatggaac tttattaggc
    16021 aataatcata aagttacaga tgaaaataaa actgcactac aaaaagttat aaaaagcggt
    16081 attaatgtaa ctttagcaac aggaagagcc ttcgattcag ctaaatgcaa tgtagatttt
    16141 cttaaagagg acatgccaat aatagcttgt aatggttcat taataagaga gcaaaatgga
    16201 aatataatat attcaaataa gattgataca agaacatgtt taaacatttt agatgtatta
    16261 gataaatacg atatttacta ccaatgtaat agtatagatt ctatgctttc gaaaaaaata
    16321 gaaggacgtg aagatagatt aagtgtattt ttaggctctg aaacagaagt aattgtaaaa
    16381 gatgatttga gagaagaaat ctttaaaaaa gatatactaa aatttgtaat catagaagaa
    16441 aaaaatccat ctattttgga tgaaataaga aaagaattga gaaaagttca aggaataaag
    16501 ataacttctt catggccaaa caatattgaa gtcatgaatg aaggtgttga taaaggtaat
    16561 gcagttaaaa ttttagctga aaaaatgaat atagacagag aagatataat tgcatttgga
    16621 gacaattaca atgacataga aatgataaag tttgctggtc ttggggtagc tatgggaaat
    16681 gcagaagaat tgattaaaca agaagctgat tatgttacag atacaaatca agacagtgga
    16741 gttgcaaagg caatttataa attcctagag ttaaaagaat cacttagctc ttaaaacagt
    16801 atataatagg aaaaaatagg ttgactattt tgtagatagt aattataata caaatagata
    16861 aaacataaaa atttagattc agtgaaaaag agagtagata tagagaaaat ctcagcgaat
    16921 tgggggatgg tgtgagccta atgataacac tttatattga aaagaacttt ggagaatact
    16981 acttgaaatt cagtatggta gtaggtaatc tcgccttaag agaatagagt gggtaaacat
    17041 tgtttaccaa ctagagtggt aacacggaat atttcgtctc ttggtctttt tgaccaagag
    17101 attttttagt ttcattgagt tacaagactt ataattaaaa tacaaaaaat taaaatatga
    17161 ggtgaaagtt atgaaattat ggggcggacg ctttagaaaa gcggaaaatc aacttatgga
    17221 agaatttaat aaatcttttg gctatgattg tgtactgtac aaaaaagata tcgaaggaag
    17281 tgtagcacat gttcatatgc aagtaaaatg tggactttta acagaagaag aaggaaagtc
    17341 tataacagaa ggtttaaaag ggatacttga agatgtagaa aatggaaagt tagtattgga
    17401 tggagagtat gaagatatac atagttttac tgagataaat ttaattcaaa gaattggaga
    17461 tgttggcaag aagcttcata cagcacgtag tagaaatgac caagttgcag ttgatatgag
    17521 attgtatgct aaagaaaaag caaatgattt ggtgggttta atatctgaat ttaaagctac
    17581 tataaaagat gttgctgaca aaaacccagt gatgatgcca ggctatactc atcttcaaag
    17641 agctcaagta gtgacattta agcatcactt aatggcatat tatagtatgt ttgatagaga
    17701 tgagaaaaga ataaaaaatg ctatagaaat attagatgaa tcacctttag gctgtggagc
    17761 tttagcagga actacgcatg atatagatag aagtataact tgtgaacaat taggatttaa
    17821 aaaagtagta gataatttta tggatggagt aagtgataga gattatttac tagagctaat
    17881 gagtgatttt tcaattataa tgatgcactt aagtagatta agtgaagagt tgatactttg
    17941 gagttctcaa gaatttggat ttgttgagat agatgattta tatacaactg gaagtagtat
    18001 aatgcctcag aagaaaaatc cagatggtgc agagcttata agaggtaaga ctggcagagt
    18061 atatggaaac ttatttggtc tttttacagt aatgaaagga ataccattag catataataa
    18121 agacatgcaa gaagataaag aaggtttttt cgatagtgta catactcttg aaatgtgtat
    18181 acaaataatg gatagaatga tagccacact aaaggtaaat gaggataaaa tgaaacaagc
    18241 agtaaaaaat ggttttttaa atgcaacaga agttgcggat tatttggtta aaaataatgt
    18301 tgcttttaga gatgcacatg gtatagtagg aagtatcgtt atatattgtg aagataataa
    18361 aaaagcaata gaagatttaa cattagaaga attacataag ttttcagatg cttttaagga
    18421 agatatttat gattttatcg actatgagag tatattaaat aagggaataa aaaagaattt
    18481 aaaataatgt atttattttt aaaagctgta aatttgaatg ttatcattta aatttacagc
    18541 tttttattgt gtaagatttt attatataaa agtaagaaac ttaaaaggag tagtatttaa
    18601 aataaataca aataaaaaat tattattaaa atgataatta atatcaataa gtattgacaa
    18661 aattatttct aaatactatt atatataata taaataataa tgaaaatcaa tatcaaataa
    18721 atgggaggaa atctaatgaa cttattagtg attggtggtc atgaaagaat ggaaaaagat
    18781 tatatggtta tggccaagaa aaaaggttat aagacaaagg tatatactac catgtcatct
    18841 aaattaaata attctatagg aagaccagat gcagttgtca tacttacatc aactgtttca
    18901 cataagatgt ctagaacggt tgagtctcaa gctaaaaaac aagatatatt aatcgtaagg
    18961 cataaaaata gtagtaaggt agcatttaat gaatgtctag atatggttga tgaatgtctg
    19021 ggaaattgtt caaaatgtaa gcttaaagac aaacaaaaac aaaaaaatat ataggtataa
    19081 aaaatacata aacataaaat taaaagtact gagataatag ttataattat tatctcagta
    19141 cttttagatt tataaggata agtatattat aaatttttta ttataatttc caactacttg
    19201 ttactttttc atattttttt tacttctagc tttttttctt tttttcttct ttatatttga
    19261 agctattata aataaaacta aaagcactag aatacctgca ataatcttaa caaaagtcat
    19321 taaaatatta tttccagtaa aaaatggaag actgctatca agattatttt ttgcaattaa
    19381 gtctatactg ttttctagtt taccattatt atatacattt aaagtaccaa ccttagctcc
    19441 tttttttata ggcaaatcaa ttttatttaa ctctgttttg gtatcataat tgccttgaga
    19501 ttcatctttt tctaagaata tcctataact attttttggt tcataaatca attcatgttg
    19561 ttttgtaaac aatacttttt tagtatctgt gtatttttct ttatcaacaa tagtagcaca
    19621 cttaaagtta tcaaatccat aatcaatcag aatacgtgag tctaaatata aatcagcatt
    19681 agttgaatta aatacagcaa cgataactct tctgccatct tttacagcac tcgataaaag
    19741 acatttacca gcagcatcag tatatccagt ttttatacca tcaactatat catattttat
    19801 atttataggt tgacctttgt atgtaatctt atcatgtgat gtcaaaaact tattagtgtt
    19861 tacaaagtat ctctcataag gatatgcttt tgtagcttca aatttaagtg acttagtttt
    19921 tacaatttgt ctaaaagtat cattattcat agcttctcta gctatgagag ccatatcatg
    19981 agctgttgtg tagtgatttg ggtctggtaa tccatgagga ttattaaaat gagtattagt
    20041 agctccaatt ttttttgcct cagagttcat gaggtcaata aatttttgta cattgccacc
    20101 accaacatat ctagccaata caaaagcagc atcattagca gaatgaacca aaagagcatc
    20161 tagtaactgc tttacagtaa aagattcccc attttttaga tacatactag agccatctat
    20221 ttgaggtaaa tctttaattt ctattacttg atttaaatct ttaacctcct ttagaactaa
    20281 acaagctgtc catactttag ttgttgaagc tggataaagc ttagaatttc catccttatt
    20341 atatagtatt ttgccagact catagtccat taaaactgca tgtttagcaa ctatagctgg
    20401 ttcattatct gcaaaagaga tattagagct tcctaaaaat gaagtaaata tcaataaaca
    20461 gattaataaa agtgataaat ttcttttcat tgtgagcctc caaattttaa attcatcttt
    20521 tagtatagca tatatttgtc aataattaaa agaaaggagt gattaatata tgaaaaaaaa
    20581 ggtaaaattt atttcgtttt ttgttttatt tattttaata atatcatcaa taatcgttta
    20641 taaatcgctt attttcaaag atgatattta tgttgtaagt aaaaaaaatt tacctaatga
    20701 aaaaacacat gttgtagaga atgaaattaa aggtgaagat aataatcaca ataaagtaac
    20761 taaagacata gataaaaatt ttcaaaataa taaaataact atatacataa gtggagcagt
    20821 aaatagacct ggaattgtaa ctatagagtc agacaagaga ctttatgatg ctgtagaatt
    20881 actaggagga acgacaaaag aagcagattt aaatggagtc aatctatcag taagattaga
    20941 agatgaacaa cattacataa tacctaaaat aggtgaagca acatctgtta caagtaatga
    21001 tgattccaat aaaccaaatc agaagaatga gtcaagaggt gagcctaaaa ataaatccaa
    21061 taaaaatata tctaacgaat caaaagtaaa tataaatgta gcgactatag aagagttaga
    21121 ttctctacct ggggttggag aagctacagc caataaaatt ttacaacaca gagaagaaaa
    21181 tggacagttt agttcaattg aggaaataaa aaatgtaaat ggtattggag ataaaaagta
    21241 tgaaaatata aaagatttaa tttgtgtaga ctaaaatata atacaaaact tacatataga
    21301 tatgttatta taaatatgta tgtatatgtg tgtacatgtg gaaatttagt aaaggaggca
    21361 cttttatgaa aaaagaacaa aaaaaactta cagagatgac aacagcaggt ggttgagccg
    21421 ctaaaatagg gccagaggtt ctggcatcag ttttatctca attgcctaaa aatgataata
    21481 tagaaaattt attagtagga ctagatacag cagatgatgc tgcagtttat aaattaaatg
    21541 atgatatggc acttatccaa actttagact tctttacacc aatggtagat aacccatacg
    21601 tatttggtca aattgctgca tcaaattcac tatcagatgt atatgctatg ggaggcaaac
    21661 ctttggttgc tatgaatatt gtttgttttc catcatgcca tgatatggat gtacttgcgg
    21721 aaatattaaa aggtgggttt gataaagtga aagaaagtgg agcacttttg gttggagggc
    21781 atactgtaga tgacaaagag cctaaatatg gtctttcagt ttctgggatt gtaagtccaa
    21841 ataaagtttt atcaaatgct actgcaaaac ctggtgataa gttaattata acaaaaccaa
    21901 ttggagtggg tgtattaaat acagccatga aagaaggtat ggtagaacaa catatagcag
    21961 ataaagtaat agaaataatg atacatttaa ataaatatgc agcaatgagt tttgagaaat
    22021 ttgatgtaaa ttcggttaca gatataactg gttttggtct acttggtcat actttagaaa
    22081 tggccaaagc ttctgaagta agtattgaaa ttgaatcaaa acatgtacca attattgaag
    22141 gtgcaataga aatggcacaa atgggaatta tacctgctgg tatgtataaa aatatgcatt
    22201 atgtatctaa agatgtagaa gttgtaggaa atatagaagt tgcagttcaa gatattttat
    22261 acgacccaca aacatcagga gggttgttaa tttcagtaaa agaagaactt gcagaggaac
    22321 ttgtaaaaga tatgaaatta aatggagcaa tagaagctaa aattataggt tctgtagttc
    22381 caaaagggga aaaatatatt acagttttat aaaatattat agagaaagag tgattgtttt
    22441 gagcaaaaga gaattgtttg caatgttgcc ttcagttgat gaagtattaa gtgataatag
    22501 aattgtagaa ataataaatg aatatcctag aagtttagtt ttagaatctg tgagagaagt
    22561 aatagattta aaaagacaat ttatattaag attaaaagaa gatgcatcaa actctgtaac
    22621 aatagagttt ggtgaaataa tagaatctgc aatagagaga gttaagttaa attactcatt
    22681 atctttaaaa aaagttataa atgcaactgg tacagttatt catacaaatt tagggaggtc
    22741 tttacttagt gaagatataa aagatgaatt atggtgtgct gcttcaaggt attcaaactt
    22801 agaatacgat ttggataatg gagaaagagg ttcaagatac tctcatttaa ctagtacaat
    22861 aaaaagactt actggagcag aagatgtact agttgtaaat aataatgcag cggcagtact
    22921 tcttgtactt agcacaatgg ctaaaggagg agaagcaatt gtatctcgtg gagaattagt
    22981 tgaagtaggt ggttcattta ggattccaag tataatggct cttagtggtg cagaattagt
    23041 tgaagttggt tcaactaata aaactcattt gaaagattac aaggaggcca ttacagaaga
    23101 tacaaatgta ttgatgaagg ttcatacaag taattataga ataatgggat tcacagagag
    23161 tgtttctata gaagaattgg ttaatttagg taaaaaatat aaactacctg taatagaaga
    23221 cttaggaagt ggagttttta tagatttatc aaaatacggt ttatcttatg aaccaactgt
    23281 attggattct attcgacaag gtgcagatgt agtaactttt agtggagata agatgcttgg
    23341 aggtccacaa gcaggtatta tagttgggaa aaaagagtat atagaaaaaa tgaagaaaaa
    23401 tcaacttact agagcactta gagttgataa gcttacaata tgtgctcttg aagcaacatt
    23461 gagaatgtat ttagatgaga caaaagctat agaaaatata cctactttaa aaatgttgac
    23521 atataaaatt gaagaattag aagtaaaagc aaataaacta tttgaaaaaa taactgcttt
    23581 aaacttaaat gcaaacataa atatagaaga tggattttca caagtgggag gagggtctat
    23641 gcctcttgaa actataagta caaaggtaat atcaataact cctgaacata tgaatgtttc
    23701 atctttagaa aaaaaactaa gacttagtga agcacatata atagccagag tgtatgataa
    23761 taaatatgta ctagatgtaa gaactatatt tgatgatgaa tttgatgtaa tagttgcgga
    23821 attgagaaaa gcatttaatt aaataaattt gagctaataa atattaaatt tagaagtata
    23881 agtatgaagt tttgattaaa aaatagctac acacacttgt gactttagtc atagcaggtt
    23941 tagagggggc aaaaaatgaa aaatgtagta attggaacag caggtcatat tgaccacgga
    24001 aaaactactc ttataaaagc attgactgga agagagactg atacattaga tgaagaaaaa
    24061 aagagaggta tttcaataaa cttaggattt acttattttg atttaccaaa caatagaaga
    24121 gctggaattg ttgatgtccc aggacacgaa aaattcataa aaaacatgtt agctggagca
    24181 tcaggaattg atatagtttt acttgttgta gcagcagatg aaggggttat gccacagaca
    24241 gttgagcatt tagatattct aagcttttta aatatcaaaa atggaatagt ggttctaact
    24301 aagtctgata ctgtagatga tgaatttaga gagctagtaa aagaagatat ttgtgaaaaa
    24361 ataaaaggaa cttttcttga agatgctgaa ataattgaag ttgattctat atctaaaaga
    24421 ggtatagaca ctcttattga aaaaatagat aaaatgagtg atgatataga agataaaaat
    24481 gaaaactctc cagcaagact taatatagac agagtatttt caataaaagg gtttggtact
    24541 gtaataacag gcactttaat agaaggaaag ataagtatag aagatgattt agttatatat
    24601 ccacaggtat taaaaacaaa aataagaagt atacaagttc atggagaaaa taaagataca
    24661 gcttatgcag gtcaaagaac agcaatcaat atatcaaatg taaaagtgga tgatataaaa
    24721 agaggagatg ttttagctgc accaaactca ttagaggaat caatgatgtt agatgtaaaa
    24781 ttatcattgg taaatcattt agataaagga ttaaagcact gggatagatt aagattgtat
    24841 catggaacta gagagatact ttgtagagca gttccactag ataaagaatt aattgaaagt
    24901 ggagaaagtg gctatgttca gttgagactt gaagaaagca tagtatctaa gaaaggtgat
    24961 acgtttgtag tgagacgtta ttctccaatg gaaactatag gtggaggtgt aataattgac
    25021 ccatctccta aaaaacataa gaaatttgat gaaaaagtta tagaagcatt aaaaataaaa
    25081 gaaaaaggcg aactaaaaga tataatagaa gagtacttaa aaaggaattt aaaaaattat
    25141 ccaaatataa aagaaataat gagctatagt ggtgctcatg aagaagatgt aaaaagagcg
    25201 cttgaagcac ttatatcaga agataaagta tttattatag gaaatatgta tatgcatata
    25261 aatcaataca ataaattaaa agaaaataca ataaagcttt taagtgagta ccataagaag
    25321 tataggctta gaaaagggat actaaaagaa gaagtaaggt ctaagataga gagtaatttt
    25381 aagactaggg agatggatat tttattagaa aaattgtcta cagaaaatgc tataaaaata
    25441 gaaaataata tagtatctct attagatttt gaggttattt taaatgataa gcaaaaagaa
    25501 atagcaaaaa aaatagaaaa aagattaaaa tcatgtggag tttcttctat actgacaata
    25561 gatgaagttt ctgaaggaaa tcataactat gctgaagtat tggagtcaat gataggtaat
    25621 aaagtagaga aattagatga tttgtatata atggacaaag atatttatga aaatgcaaag
    25681 aacattttga taaattatat aaaagaaaat aaagaaataa cattaggaga atacagagat
    25741 ttgattgatt ctagcagaaa gaattgcatg attatattgg aaaacttcga tagaaacaaa
    25801 ataactaaaa gagtagaaaa caaaagaatt ttgttttagc agaaaatgtc tgtttttgct
    25861 ttaaggtata aagaaggaat tataatgtcg agtatcgtat aattaattag tataaaatat
    25921 taattaagag gaagtgtaaa gtattgaaga atataatacc tgatgtaaaa ccagatataa
    25981 aagaaagaga agacatgagc cttttattta taataatggg ctcagtactt ttattattta
    26041 ttataaaaga tatagagaaa tatgaaactt tattacatgc catatatacg atatttttag
    26101 tagctacagg agtaattata tttaatacta caaaatttaa agtagattca ttttctacat
    26161 ttttaggatt aatttttata gctactggag tattggagtg tatatattta tttaattcct
    26221 tggggattaa aactaagtct ataatggaga ttaacatcac aatatcagca ataacagatt
    26281 tatttcctat actgggtgta tacttaagtt ttaaatttgt taaggataac aaacaaattt
    26341 attcaagtat aattttattt atagcaactg ctacattaac aataacatct ttattcataa
    26401 tatcaggaat ttgtgactat ctgggaaatg gtaaatcaca atatgcttta ggagttataa
    26461 tatctatatt cataataatt atttctatca ttagtggaat tgaattaaat tcaagttcaa
    26521 ataaaggtaa atgggaatat gatgaaaaaa agatttttaa cagaataata gtaataataa
    26581 ttttatcaag agttccaaat ctattgcata tagttattga taatagaaat gtagagcgga
    26641 tattatcaca gataataata aatgtagcct tatattattt atataattac atagtatcta
    26701 agaatattaa gaaaacagca ctggaattgc atgatacgaa tgaagaatta acaaaaaaaa
    26761 cggaaagttt aaaagaaaag aataaaaaat taatctatga gacagaaaag atagaggaac
    26821 ttaagggaat acttatgaaa agagaatcta ggctacaatc tacattagat gtagcagtaa
    26881 atagcatagt agtgtttagc aaagatggag aaattacata tgcaaataag agctttagaa
    26941 atacttttgg agactataaa gaacaagata aattgactga taaaataaaa aacttcaatg
    27001 atttgataga aagcattcat tatgtgtttg ttcatgagaa gaatgcagag aaacttatta
    27061 gtacaagcga taataaagtt tatcaagcta tatttgcacc tttaattatt gcttcacaaa
    27121 cagaaggagt attgtgtgta ctagaagata agactaagaa aaaggagtac gaacgcaaac
    27181 ttattgaagc aaataagaga agtaaagatt ttttagaaag tattggagat ggcatagtag
    27241 tgcttgaagg taataacaaa atatatgtta ataatgcatg tagggaaatt tttaaaaata
    27301 atttagagag tattgatttt tcattagtat gtaaaagtga agaaagtata gaaaaaagat
    27361 atgtaataga tggtgaagta aagtatgtag agatgagttt ttctcagtat actaatgctg
    27421 gtactaataa aactattatt gtaatacgtg atacaacctc tcgaaaaata tctcaaataa
    27481 aacttgagga aagtcaatca tcatattcaa gatttataga tatattacct gatggcatat
    27541 gcttattaaa agaagattta agtataaact atgcaaataa gtcgttttta gatatgctag
    27601 cttttacaaa catagatgat ataaaagatt ctaatattaa actattaatg aatgcgaata
    27661 ctgaagaaaa aatgaaattt acggataata tggctaaagt tttaaatgaa aatagaagta
    27721 tacttttact ggaatatgaa ttgataaata gttatgatga tatagtagaa gtagaattaa
    27781 gtgcattacc ttttgctata tacaatacta gatacataat gcttattata aaagatttag
    27841 tacataagaa atattccgag caagcagaaa aagaactgct tgaaagattt aaaacagata
    27901 aaatcaaaac ggagtttttt gcaaatatgt ctcatgaatt aaaaactcca ctaaatgtta
    27961 tatctagttc aaatcaactg gtagattctt tctatagaaa tgaaaagata aaagattaca
    28021 ataacaatat taaatctcat gtggatttag ttagacaaag ttcttatagg cttcaaagat
    28081 taataaataa cattatagat ttaacaaaga tggagtctgg gttctataca ctaaaacttg
    28141 cgaaatacaa tattgtatct gtaatagaag acttatttat gaatatagaa gagtatgcac
    28201 ttagaaaaga cataaaaatt ctttttgata cagaccttga agaaattaat gtttatatag
    28261 acaaggttga aattgagaga attatgttga atctattgtc aaactgtatt aagtttactg
    28321 ataatggagg ctggatatat gtaagtattc attataaaat agataaagta atcataagtg
    28381 taaaagacac tggagttgga ataccacaag ataaattaga attgattttt gaagaatttt
    28441 cacaagttga taagacttta tccagaaata ctgaaggaag tggaataggg cttgctatag
    28501 ttaagaatct agtaagtctt catggtggag atatagaagt agtaagtgaa gtgaataaag
    28561 gcacagagtt cttaatttca cttccaatga agggatttag tagtgaacat tacacagaag
    28621 ataagagaat atataatatt caagaaaaaa taaaaataga attttctgat atatactatt
    28681 aaaaatgatt atgagcaaaa ataaaataaa aatactattt gtttaaatat ttaagttgta
    28741 agaaataggc tatcataagg taaattatta tgatagccta tttttagcta ggttttatat
    28801 ctatatgtga gaacatataa tctctaaatt accttcaaaa ctaaaatctc caaagtcgtt
    28861 tggcagtata aaatgcatac ccttttttaa attatattct acagaattgt gtataagttt
    28921 tccatttcca tccaacacac tgtataaaga aaaaggtgta ttgtgtgtaa aattacattt
    28981 tccaaaaaca tctaatttat aaacactaaa aaattcgttt gacacaaatg ttgtgcattt
    29041 aaagtctgat gttgatacga ttttatagtc agtatcgaaa tttatatgag gaacattcgt
    29101 aacatctatt gatttttgaa catgaagttc acgcttatta cctgaattgt cagttctatc
    29161 ataatcatag actctataag tagtatctga gttttgttga gtttctaaaa tcaatgttcc
    29221 tttgcatata gcatgtatag taccacttgg aacatagaaa aagtctccct tttttatatt
    29281 aacctttcta agtagtttgt cccattcatt attatttacc atatttacaa attctttatg
    29341 agattttgca ttatgaccta ttataatttc tgcatcatca gaacaatcta ttacatacca
    29401 acactctgtc ttacctaact ctccattttc atttttctta gcatattcat catttggatg
    29461 gacttgaact gataaattat catttgcatc caatattttt gtaagtaaag gaaacttatc
    29521 accaggtgtg tttccaaata attctctatt tttattccac aattcagata gttttttacc
    29581 tttatatttt ccattttcta ttaagcaatc tccattttta tgagagctta tagcccaaca
    29641 ttcaccagtt gttggcgaat ctatttcata attaaattta tctttaagtg cagtaccacc
    29701 ccatattcta tccataaaaa taggttttaa aaataatggt tccataatcc tgttcctcct
    29761 atgatattaa atttatccta caaataatta tatataaata gattataaaa tcaatagtaa
    29821 aaaagttttg tcccttgaaa tgacataaag tataaggagt tattaaataa gataaactat
    29881 gatatataat ataaagttct aaattggagt gataattatg gagttgttta aggcagaaag
    29941 caaaaaatat gaaaaagaat ttttaaaatt attggagcaa tgggttagta taccttcatt
    30001 ttatgataga aaaactgtat ctaaagatat gccttttgga aaaggagtat atgatgcatt
    30061 aaactggttt gaaaatctag gtagagaaaa caatttcaaa gtaaaaaata tagataatca
    30121 tgctgttcaa attgaatatg gaaatggtaa agaatatgta gatatatttg gacattgtga
    30181 tgttgtaaat ccaggtgaag gatgggatag tgaaccattt aaactaaata ttataggtga
    30241 taaattagtt gctagaggtg tatctgataa taaaggacct atgatagtga attttttagc
    30301 actaaaaatg ataaaggatt tagatattaa tttaaaaaga aaggttagat taatagctgg
    30361 aggaaatgaa gagagtggat ttaaatgtat aaagcattat tatagcaaag agccatatgg
    30421 tgtatgtgga tttactccag atgctaaatt tcctgtatta aatggagaaa aaggtggagc
    30481 aataataaag ttaatttcaa atatagacga taaatcttta tatataagtg gtggaataga
    30541 gtttaataca ataccagata aagtttatat aaagaatgta gaaaaattgg gtaaagataa
    30601 tatatgtttt gatattaaca atatatcgat aaattatgat aatggcaatt atattgtgta
    30661 tggaaaaggt ggtcattcat ctaaacccga aaaatcaata aatcctatat tagctacaat
    30721 taaacttttg tcagaaaata ttgatgaaaa atggacaaaa gatttatata agttgataaa
    30781 tcaagataat ataaatggaa acttatttgg tttaaatatt gaggggaaat gtgggatttt
    30841 atcaatagtg ccaacaataa taaatatagt agatggaaaa ttagaagtag ttttaagcgt
    30901 tagatatcca gaaatattaa ccattgaaga tataataaaa aaatttaatt tgtatatgga
    30961 gcaaaataat attaataaat ttgagcttat tggggaaaat ttaaagcaag caaattatat
    31021 agatagaaat tcaaaacttg taagaagttt gcatgatata tatataaagt attctggaga
    31081 tttgaaaaat gatgttagag taactagtgc aggaagttat gcttctgaaa tgaataattc
    31141 agtaatattt ggttgtgaat ttcctgatgg tagctttggc aatgtccata gtgcgaatga
    31201 atttgctagc ttagatagat ttataactgc aataggtata tatgcagagg caataattac
    31261 attatgtaat aaaatataaa tacaaaatgt cccttatata gacatattat atatacaatt
    31321 aaaattttac ttgatatata attgaaatca aagagaaggt gatacaatga taactaagaa
    31381 acatgcaata atagtaaaga gtttaagcaa taaagatgga tatatgacat caaacgaatt
    31441 agctatcaaa ttggatgtgt ctactaaaac tattaaaaga tatatagcag atttaaatag
    31501 tgttttaagc aaatatgatt tggtaatagc ttcttctaga ggtataggat acaagttaag
    31561 cggttctaaa aacaatatag ccagagctgt taaagaagca aataaatata ttgatggttt
    31621 tttagatgac tctgaagagt caagaatgtc aaatataata tgtatgctta ttaatagaaa
    31681 ttatatgagt atagaagcaa tggcagaaga attaaatcta agtatagccg ctataaataa
    31741 attgtctagt aagcttaaaa gaaaacttga aaagtatgac ttagttataa aatctaaacc
    31801 ttactatgga agctatatac atggtgaaga aattaatata aggcaattaa ttactgacta
    31861 tgcaataaaa ttagatgaaa aaagtaaagt gaaggtgttt ttagatgaca ttagtgaaaa
    31921 cgatatatac tgtatagaaa gtattttaga aaagcactta agagaaaaag atacaataat
    31981 ttcagataaa gattttaatc ttttgctttc aaaaataatt gtttctgtat ttaggagtaa
    32041 gagaggtcat agtaacaata taaacttaat ggatacaagt tatagatttc ataactacta
    32101 ctttatagaa aatctaatga aagaaatatc tgataaaatt ggatttaaac ttattgaaga
    32161 tgaagtaatt tatatttcaa attattctgg tgtaatagct tataaaggta cacaaggaag
    32221 aaaaaacaca agtgaaattg aggaacgaat aagtagtgtt ataagtagtg cacttcaaga
    32281 tatattcctt atttcaggta gtgattatac aaaagatgat gagtttatgg ttgcaatctc
    32341 tgaccatata aagagatttt taaatagagc tagagctaat gtaaaatcaa ataatccttt
    32401 acttcatcaa ataaaagaga agtttcctat agcttttaat ttagccgtgt ttttatcaaa
    32461 taaactagaa actgagttta atttaaaact tgatgaagat gagcttggat atatagctat
    32521 ccactttgct gcttcaaatg aaagaatgaa aaaaaatact agtaagaaaa tttgtatagt
    32581 ttgtcattat gggataggaa caggacaact tatttctgaa aagctaaaac agaatataag
    32641 tgatttaagt gttgtaggtg tttatccagt tagatatctt gatatggcta taagtcaaga
    32701 tgttgatttg atagtatcta ccgttgaatt aaaaggatat gaaaaacctg tcttatatat
    32761 agaaaatata tttgatgata gcttaattga aaacgtaaac aaagcctttt atgaaaagga
    32821 agaaagaaga aagataataa gtaacatgtt tgatgaaaaa gcttttttca gtataaaggc
    32881 tagtactaaa gaagaggtca taatttcact ttcaaataaa ctaaaagaaa gagattttat
    32941 agaggaaagt tctataaaaa gtataataga tagagaaaat atttcatcaa ctgaaatagg
    33001 aaatctagta gcaatacctc acacaatagt gaagggagat aaaaaatcta taataggagt
    33061 tggaatactt gaaaatccaa taatttggga taagcaagag gttcagctag tatttatggt
    33121 attttttaat actaaagaaa agcataattt ctcgatattt aaataccttt ataattttat
    33181 aaaagatgaa ggaggagtaa gaggaattat taaaatatgt gactttaata aattaatggc
    33241 actgataggt aattaaggag gaaattaata atgggaacaa acatatttaa caaagaatat
    33301 gtatttttaa atgttgatgc taagtcaaag gttgaagttt taaaatttat atcaaaaaaa
    33361 gctaaagact taaatttggc agaagatgag agcttagtat atgaaggttt aatggctaga
    33421 gaagaacaat ttactacaaa tttaggagaa tctatagcaa tacctcacac taaaaatgat
    33481 gcaattgaaa atccagcagt agtagtattg aagtttaatg aagatgttgt ttggaatgaa
    33541 ggtgaggata aggttaaatt agcaataagc ttacttatgc caggaaaaag taaagagaat
    33601 attcatctta aattattatc atctctttca agaaaattaa taaataaaga atttaaagat
    33661 tctcttttaa aaagtgataa tgttgaagaa atatctaact taataaatga agctttaggt
    33721 ttataattaa atactaaggt tataaaataa aaaaataatt aactaaaaat aggaggaatt
    33781 tgaaatgaat aaaaaattag tagcattatg tgcttgccca atgggactag ctcacacttt
    33841 catggcagca gaagcaatag agcaagcagc aaaggcatta ggttatgaag caaaagttga
    33901 aactcaaggt gctgatggtg tacaaaatga gttaacaaga gatgatatat taggagcaac
    33961 tatgataata catgcagtag caataacacc agaaggtatg gaaagatttg atggttgtga
    34021 agtttatgaa gttgaattac aagaagctat aaaaaatgca gaaggtgtta taaaagaaat
    34081 agaagaagat ttaggaatat aataaattta ttgtggagga aatagaatgg caattaagaa
    34141 aaaagttata aacagttcag gtgcttctac aacaggagga aataatgtag gaaaatctac
    34201 tccatctagt ccaactcaat caaagggaaa tggaaaatgg aaagaaataa gtaaacatat
    34261 aatgacaggt atatcatata tgataccagt tttagtaatg ggtggactta taggggcctt
    34321 atctcaatta ataccatatg ctatattagg acttgaccca tctgtaggta tagttgatgc
    34381 tatgaactca ggagaattta cagggttcaa gcttagtctt ttaaatatag cacaattaat
    34441 gtcaaatttc ggatttactt tgtttggatt tgcgatacca ctgtttgcag cattttgtgc
    34501 aaactctata ggtggaaaaa cagctttaat tgcaggattt ataggtggat atatagctaa
    34561 taaacctgta ggtgtaccac aattcattga tggacaatgg actgaagttg ttccagttgc
    34621 atcaggattt ttaggtgcaa tactaatagc attcataata ggatattttg taaaatggtt
    34681 aaataaatct ataaaagttt ctcataactg gttagctttt aaaacaacat ttttaatacc
    34741 attaatagcg tcattagctt gtatggtatt gatgatattt ataataactc catttggtgg
    34801 attaattaat gaaagtatga aaaacttctt aacagcagca ggagcagctg gagaatatgt
    34861 atatgcaaca gctttggcag cagctacagc attcgactta ggaggaccaa taaataaagc
    34921 agcaggattc gttgcacttg gtttaactac agagaatgta cttccaataa cagcaagaac
    34981 aatagctata gttgttcctc caattggatt aggattaaca acattattag ataaaagatt
    35041 agtaggaaga agagtatatg atagacaatt ctatcaagca ggaaaaactt ctatattctt
    35101 atcatttatg ggtatatctg aaggagcaat accatttgca cttgagagac caggttttgt
    35161 tataccttta aacatagttg gaagtgtaat aggagctatt acaggtataa ttctaggagc
    35221 aattcaatgg ttcccagagt cagctatatg ggcatggcct ctagtagata acttatttgg
    35281 atatataata ggtatagcag ttggtgctat attcatagca gtaggaaata tattctatag
    35341 aaataaatta ataaaagatg gtaaacttgt tgtagattat atcgactagt atttaatttt
    35401 tactatctat aaataacttt ggctggtaat atggttttaa tcaatattac cagccttacc
    35461 tatatgatta attaaaggcg gtggagataa gatatggata agatagaaaa agtaagagag
    35521 tattttagag aatatgatat agatggattt cttataaata gtcctacaaa caagttttat
    35581 gttggaaatt tatttagctc ttcaggttat gtttttataa cgaaagaatc acaatatata
    35641 atagtagatt ttagatattt tgaagaaatt aaaagaaaat ctagtttgtt taatgtagta
    35701 ttaatggaca aaactagaac tcattttgat ataattaatg atatttgtag agagcagaat
    35761 ataaaggaaa ttggatttga gggaaatgaa gtatcttttg atttatatag aagtatgagt
    35821 aataagttaa gtgcaacctt aaaatcagtt gatttatcta cattaaggga aacaaaaaat
    35881 gaagacgaaa taaaatatat aaaaaaagct tgtgaaatag ttgatgctac attttatcat
    35941 atagtagact ttataaagat tggtatgact gaaaagcaag ttgaaaatga aattgttaga
    36001 attataaaag atttaggtgg tcaaaaagaa tctttcgata caatagttgc atctgggctt
    36061 agaggagcat tacctcatgg aaaagcaagt gaaaaaatta tagagtatgg agattttgtt
    36121 acttttgact ttggtgctaa gtataataat tattgttcag atattaccag aaccatttgt
    36181 atgggtacta taaataaaga gttagaagaa atatataata tagtaagaaa agctaatgaa
    36241 gagtgtataa gagttttaag accgggaatg actactggag agatagataa agttgcaaga
    36301 gacataattg gttcatatgg atatgccaat aattttggtc ataatctggg tcatggtgta
    36361 ggaattatgg ttcatgaata tcctgcctta gctcctgaat caaatgaagt attaaaagaa
    36421 ggaatgattg taactataga gcctggtata tatgttccaa gtcttggagg cgtaagaata
    36481 gaagatgatg tactcataac acaagatgga tgtatgagat tgactacatc tactaaggat
    36541 ttaatagttg taagctaaaa ataaattaga taaatatttt ataacaataa gaaaagaaga
    36601 ggtaaattta aatgtataat tttgatgata aaccagatag agtaagtgaa aagtgtagaa
    36661 aatgggattt aaatattata agagataaat ttggagatat tagagaagat tttgtaccaa
    36721 tgtggattgc tgatatggat tttaaaatac caacagaaat agaaaacaaa tttattgaag
    36781 ctgtaagaag aggtgtattt ggatatacat actgttatga tgaattttat gattcagtta
    36841 ttggttggca aaaaaatatg catgaggtaa atgtagaaaa agaatggatt acattaactt
    36901 atggaactgt atcaacactt cattatgtag tacaagcttt ttgtaagaaa ggtgatagta
    36961 taatattaaa cacaccagtt tatgacccct ttgaatcatc agcaaaaaaa caaggtgtaa
    37021 atgtaatttg taatacatta gatgttgtaa atgatagata ttatataaat tttgataaat
    37081 tagaagttca aattaaagaa aataagccta aattaatgat gttttgtaca ccacataatc
    37141 catctggaag gatatggaca attgaagaaa tgacaagggt agcaactata tgtaaagaaa
    37201 ataatgttat tttggttgca gatgaagtac atgcagagca tattcattat ggtaaattta
    37261 attcaatact taagattgga aaagagcttt tagaaaatgt tattctactg acatcaccaa
    37321 ataagggctt taatcttggt ggattaaaga cttcttattc aatagttata aataagaata
    37381 taagggataa atttagaaat aaattaaagc aaaattctat aacttctcca aatgtgtttg
    37441 gaataatagg attgataacc gcttataatg aatgtcatga gtggttaagt ggtgtaaatg
    37501 aatatataaa atcaaattat gaacttttag aaacttgggt aaataaatat aataagataa
    37561 aattgatgaa aatggaatca tcttacttag cttggatgga tataagtgga ttaggtataa
    37621 gtgcaagtga gtttacagat aaattggcta tagatacagg agtattatta gaagatggga
    37681 gtcattttgt aaaagatggt gagaagtatg ttagaataaa tttaggaact caaaaggaaa
    37741 atgtaattga agctttaaat agaatggatt tatttttaaa gtctttataa aaatttggtt
    37801 gaattagtat tttatataaa tttaagctat taatatggta tatacataag tagaatttgt
    37861 tttagattac ttaagtatat accatatttt atataaaaat taaatttgca ttagtcatgt
    37921 gataactatt taaattcata tgtattttgt atgtataata gatataatta ttatttaaac
    37981 ttattgttta tttaattttt caatagaaaa agatttatct gtaagtttaa aattatcttt
    38041 tataccctta gttaaatata ctttcttatc cttagttatg aatatagcat ctacattatc
    38101 aatttcatta attaaatcca tacctttttc aagaccaagt ccaaatgtag aagtggataa
    38161 ggcatcacaa ttaatagatt tatcagaaat tattgtaaca ctacttagat tgttttcaaa
    38221 aggataccct gtaaatggat ttaacatatg atgatatatt tttccgtctt tttcgataaa
    38281 tctttcataa attccagaag taacaacaga tttatttgtg gtttctatgt ttcctatgga
    38341 ttcaccattt ttactagtgg ggtcttgaat gcctatttta aaaggtttat catttttacc
    38401 atcttctaaa gtaaatatat ttcctcctaa gtttactaaa ccttttttta cgtcctctga
    38461 ttttaaatag gctacaattt tatcagcagc atatccttta gctatggcac ctaaatcaat
    38521 tttcatattt tctttggtta attttataga tttatttttt tcatccaata tgatgttctt
    38581 ataatcaata agaggcagaa gtttttgtat ctcagaatca cttggaactt tagctttatc
    38641 tgttccaata gcccataaat ttgataatgg accaattgtt atgtcaaaat atccatctga
    38701 taatttggaa tattgtatag cttcttttac gacgaaaaat gtatcatcag aaactctgac
    38761 aaatttttta ccagcattat catttatttt agaaacatca cttcctggta tatgagtgct
    38821 cattttgttg tcaatatatc ttaaaattga atcacattca tttaagattt tatcactttt
    38881 ggattctttt acattaaata tagtaacttc gtttactgta ccaaggtagt agctagtttt
    38941 actatattta gtattctggc ttgaactcct aaaaaatgaa aataaaatta atgctaaaat
    39001 caatatcaca aaaataaatg tgattttttt cttattcatg gtatattcct cctatgaaat
    39061 tgtgttatta ttttattata acataatttc ataggaggac aaaaaatgaa gaaaaaagac
    39121 attcttctta ttttaggcat tttggttgtt attatagcat gttatgggat aataaatgtt
    39181 ataaattcta aaaatgctgg aaatattgag atttatgtag ataataaatt gtataaaact
    39241 gtttcaataa atgccaaaga agaatttaaa atagagaata gaggggggta taacatagta
    39301 aagattcatg ataaaggggt tgagatagta gatgcttcat gccctgataa ggtttgcgta
    39361 catactggat ttataaacaa gccaagtcaa agcatagttt gtatacctaa tagagtgagc
    39421 ataaaaataa atacaaatga aaagaatgat aatcaagaag atataatttc taaataaaat
    39481 aataaaaata attgaaagga attggtgata attatggtta acttaggaaa cgattgggat
    39541 gaattattga aagaagaatt tgaaaaagat tactacttaa acttaagaaa atttcttata
    39601 gaagaatata aaacacgcca aattttccca aatatgcaca atatatatga agctttaaaa
    39661 cacacttcat acaaagacac aaaagtctta atattaggac aagaccctta tcatggagat
    39721 aatcaagctc atggtttagc tttttcagtt caaccacaag tgaaaactcc accatctcta
    39781 ttaaatatgt ataaagaatt aaaagatgat ttaggttgtt ttatacctaa taatggatat
    39841 ttaatgcctt gggcagacca aggagtgtta cttttaaata ctgctcttac tgttagagcg
    39901 catgaagcta attctcataa gaacaaagga tgggaaattt tcactgatag agtaatatct
    39961 attttaagtg agcgtgaaga cccagttatt tttgtactat ggggaagtaa tgcacgtaaa
    40021 aaagtagagt tgattgatac aagtaaacat tatattttgg aagcacctca tccaagccca
    40081 ttgtcagcaa gtaaaggctt ttttggatgt aaacacttct ctaagataaa tgaaattttg
    40141 aaaaagctag gaaaagaacc tattaattgg cagatagaaa atatataaaa gtaaaaggta
    40201 acaaaatgat aacaaaacaa caataaacaa tgacattgtt gtaactaata gaaatatgct
    40261 taaatagttg aaaatactat gtatgcatat ttctattttt ttgtcaagtt gacaactctt
    40321 gaaaaaatag ttacaattta gttacacaaa aaacacaaat aaaaaaagaa acttacaaag
    40381 cagaatttta tgaagcaaaa tatatagtgt aaaaaatttt agggaggaaa ttttatatga
    40441 attttaaaaa attgagtaat gctaaagtct cggtaatggc agttgtttta tcagttggaa
    40501 tattatcggg atactctgcg cttaataaac aagtaacatt agtagtaagg ggagaagaaa
    40561 gaactatatc aacatttagt tctaatgtag gagacctttt agaatctcaa aacattagct
    40621 atgatgcaaa tgatatagta actttagatg aaaatacaaa gttatctaat ggagataaaa
    40681 tagaagtaat tgatgtaaag gaaaaaacag ttgtagaaac taaagacatt ccatttgaag
    40741 ttacagttgt tgaagatggc tctttattaa agggtgattc taaggttaaa gaagaaggaa
    40801 agtctggtaa aagtgaatta atatataaag aaacttatca caatggaaag aaagttgaaa
    40861 aggaatttgt gaaaaaggtt gttaaagctg agccagtaaa taaggttgta agcaaaggga
    40921 caaaggtaga aatgcaagta gcctcatcaa ggggagaaag ttcaagaaga atggcttcat
    40981 catcatctag tagcagtagt agtaacaatg gtaaaaatat gagagtggta gcaactgcat
    41041 atactggtca tagtataact gcaacaggaa caaaacctaa gtggggaaca atagctgtag
    41101 accctaaggt tataccatat ggaactaaag tttatatacc tcaatttgac atggtgttta
    41161 ctgcagaaga ctgtggtgga gcaataaaag gaaataaaat tgatatctac atgaatgatt
    41221 caaaaacggt ttataactgg ggaagaaaaa ctatagatat acgtatatta aaatagttaa
    41281 ataatttata tttttactgg aaattatatt ttgattatat agagaagaaa ctctttatag
    41341 attcttaaaa tataatttcc agtttttatt ttggatatgt aataaaacag gtaaatttta
    41401 accatgtata gataaaagct atttaaatta taatttacta tcagataaat ctataaaaat
    41461 tgttgcaaag agtcaaaata tatgatatta tagatttcgt tgagaaggat ttcattatgg
    41521 gagtggatgg gtgccggtgt gccctctagt cttcaaaact agtatgaggg gttaagagcc
    41581 tcttaggtgg gttcgattcc cacgcattcc cgccaatatg caaaaggtat cttttaatta
    41641 aaagatacct ttttaaattt attttaagat aatttatttt taataatata taatgttttg
    41701 tattatataa tgtaaatttt ctaatactat tatatattta gataaaaatc taggagtgtg
    41761 gaaagatgga aaataatttt acaacgagaa ctagttttct agttggagat gatgggatag
    41821 aaaaacttaa taattcaaat ataatagtat ttggagttgg aggagttggt agttttactg
    41881 ttgaagcttt agcaagagct ggagtaggca atattactat tgtagatttt gatgatgtag
    41941 atataaccaa tataaataga caaataccag ccctacattc aactgtagga aggtacaaag
    42001 ttgatgtcat ggaagaaaga atattagata taaatcctaa tatcaatata aaaaaaataa
    42061 gaagtcttta taataaagat actagtgacg aaatactaac tgaaagatat gattatgttg
    42121 tggatgcgat agacatggta agttccaaaa tacatctaat tgaaacttgt gaaaaaaaag
    42181 ggttgaaaat aataagttct atgggtatgg gaaataaatt agacccaact aaaatagtcg
    42241 ttacagatat acacaaaaca agtacttgtc ctctagctaa agttatgagg aaagaactta
    42301 gggatagagg tatcaaaaag ttaaaagtag tatattctac tgaacaacca atagaactta
    42361 agaagaaagt aatgaatggt agaaaagtaa cacctggtag tgtatcattt gtcccatctg
    42421 taggaggttt aataatcgca tctgtaatag taaatgaact attaggacaa taagttttaa
    42481 atattttaat ttataaattt tatatacaaa tttgaaggct agaagcatga atataaagca
    42541 attttatatt catactttta gcctaattat tttatattac cttattttat gtagttgtag
    42601 ttttattttt tagattatgt atctatttca taattatatt ttgtaaatat aatttctcca
    42661 tcactataaa aaacaatatc tcctattcta tctgttctat aaattgatac atggttttgt
    42721 tttagattat taataacctc cctatgtgga tgaccatatt gatttttata tccacatgat
    42781 attgcagcta tatctggact aatttttttt ataaattcta aagatgaaga agaattactt
    42841 ccatgatgac ctatttttat aaaattaata ttatttaatt taaaagaatg taaaatttct
    42901 ttttcatttt cttcttcagc atcacccata aataaaaaag aattatcgtt aaaagttaat
    42961 ttgaaaacta tagaatttaa attagattct tcttgtatat atgatggact taatacatat
    43021 atatttatat tgttatctat gtttaaaaca tcatttttat agagatgctg aatagataag
    43081 tttttatccg tacaagaatt tattagattt tgataagcct cactatcagt tgattgttca
    43141 ggcatatata tggagtttac attaaatttt tttataacat tatcaagact tcctatgtgg
    43201 tctgaatctg gatgagttgc tattataata tcaatagttt ttattctttt ttgtctaaga
    43261 taactaataa ttatattttc gctatcttca tcacctccat caattaatat attcttattt
    43321 gtgggtgttt gaactaaaat actatcacct tgtccaacat caattatatg tatagatagt
    43381 agagattttt tgtcacagcc gattaaaagt gatattataa taagtattga taaaaaaatt
    43441 ttatttctca ataaaaaatc actccattca ttacatgttt atataaattt atgatgggta
    43501 atataagata tatatgactt attatatttt atattttaaa caatataaat gaaattaata
    43561 ccataataaa tttggagttt tttatatata caaaataaaa tttttaaaat taagcaataa
    43621 aaaaggtagg aggattttat gtttttcaaa gatattgaac taaattcaaa aaaagagtta
    43681 gacccatatt ttgatttagt agattatgaa gcttgtgagt actgttttag tactttatat
    43741 atgtggcaac atgtttataa gacaggatat tatataggtg aagattttgc cgttttagtt
    43801 ggggaatacg aaggagatag tttctcaata ttaccacttg ctaaaaaaga taaacttcca
    43861 gaagttgtag attttgtcct tgaatatttt tctaaaaata ataaaaaaat atacttaaga
    43921 ggtattacta ctgaagtagt agagttttta aaagaaaaat atccaggtag atttgagtat
    43981 atagaagaaa gagatttatt tgactatatt tatgatgcag aaagtttaag aactctagct
    44041 ggtaaaaaga atcaaaagaa gagaaaccat ataaactatt tcttaaaaga gtatgcaggt
    44101 agatatgaag ctaaattatt agataaagaa aactttgacg agtgtttagt actaatgaag
    44161 gaatgggaaa gtaataagga agaaaataat gaatttgatg aaagtatgga tgacgaatta
    44221 ataggtatca aaaagatatt taaccattat gacatattaa aagataaggt aaaagtgttt
    44281 ggtgtttatg tggatggaaa attagaggct tttagtatag gagaactttt aaatccaaat
    44341 atggcattga ttcatataga aaaagctaat cccgatataa gaggtctgta tccatttata
    44401 aatcaacaat ttttggtaag tgaatttaag gacgttgagt ttgtaaatag agaagaagat
    44461 ttaggtattg aaggattaag aaaagctaaa ctttcttatc atccttgcag atttgttgaa
    44521 aagtacagtg ttagggaggc ttaatagact atatggagat taggtatgct aaagaagaag
    44581 agatagaaag tataaaagag atttggagtt attgttttaa cgatacggag agttttatga
    44641 agtactattt taatgataaa tataaatctg aaaatactgt agtagcttta gatgaaggaa
    44701 aaattatttc ttctcttcag ctaaatcagt ataagttatt actaaatagc aaggtatata
    44761 atacatcata tgtagtagga gtttctacac ttccagaggg aagaggagct ggatatatga
    44821 acaaagtaat gaaatttact ttaaacgaat tgtataaaaa agggcaatta gtttctatat
    44881 tgatgcctat tgactataga ctttatagaa gatttggata tgagcattgt tacgaccaga
    44941 ttgaatatac tattaacaca gatgatttaa aaaattttaa gtcaagtgga aaaatgataa
    45001 agtctaattt atcacaaatt gatgatttga tacgaataga tagaactttt ttaaatgagg
    45061 ttaatggtaa tgtgttaaaa gatgaacatt attatgaaaa cttatttaaa gagattcaaa
    45121 gtgaagatgg atttttatac attcatgaag gaaatgaaaa agatggatat atagtttatt
    45181 ttcttcagga agataaaatg tttgtcagag agttatttta taaaaatata gatgccctta
    45241 aatcaatgct taaatttata tataatcaca atactcaatg taagatagtt actatatcta
    45301 ctcctacaat agataagata agatttatat tagacaaccc taaagatagt gatataaaaa
    45361 taaaaccttt tatgatggga agagttataa atgtaaagaa gtttattgaa gatatagata
    45421 ttgagaagga tattaatagc tcatttaatt tattaataga agacaagttt atagatgaaa
    45481 ataatggtct atttaaaatt tctatacaga ataagaaggt atctgtagag cagttagata
    45541 aaaaaggtgc agaaaagcct caagaagatt ttgatattaa attagatata aataccttaa
    45601 cacagttatc attttcttat atagatgtaa atgaagctat tttcttaaat gatataaaag
    45661 atgtttcaga agaaacacta gaaacactta attgtatttt ttctaaaaaa aatacctata
    45721 taaatgaata tatataggta gaatacgtta aaagatttta aaaatctttt gacgtatttt
    45781 tttgtttaga taacaattta tcttgtttaa aaattttcta tttgaaaata atctaaataa
    45841 tatactttta tatgggagtg attataattc aaataagaag accattatta attatattaa
    45901 tgtttgtggt agctatatca tttatcatta caaataacac aaaaaacgac gaagaactta
    45961 atgataagat aataactata caaggggttg tcaaaggaaa aattgaaaag aaaagataca
    46021 atcagtacaa ggtaggggtt tttctaataa atgattatac aaaaaataaa aatttgaaga
    46081 ttggtcagaa agttaatatt acaggtaaat tcaaaagttt agataaaatg aagtatgatg
    46141 attttgatta tggaaggtat ataaaaagta ctggatataa aggtatagtg tatataaata
    46201 actataaaat tattgataaa aataaacttt actctttaat aggggaaata aagttttata
    46261 ttagtaaaac ttataggtac ttatataaga aaaactcaga ttttataaat tctatactat
    46321 tagcagaagt tgaaaatttg actgaggaac aaaaagaaat ttttactaga actggaacta
    46381 gtcatgtaat atctatatca ggtcttcata caggaatatt atgtgtaatt atatcctttc
    46441 tattaagagg tataaataaa ttgtataaat tattaatact gtcgattttt ataactttat
    46501 attgtataat ggtaggtgcg tctccatcca taattaggtc tatagcattt gttatgattt
    46561 tttatttatc aatatttatt gatagaaaga aagatggaat atcagcattg tctctaattg
    46621 ggataatttt aattatgaat aacccctatg ttatatataa tgtaagtttt caattgtctt
    46681 ttttagctac actttctata ttaatattct ataataaaat aaatagtatt ataaaattaa
    46741 gtatggtatc attgacaata tcatcaaata tattaacttt acctataatt tattatacat
    46801 ttaaaggtat accattgctt tcaattatag gaaatttaat tatagtacca tttgtgggag
    46861 taataatgta tttaagtatt gcaagtttaa tcgtatttaa agtaagtgta gtaatagcta
    46921 aaattatatc tttttttaat agtacattga tagaaagcat atttttttta ctagaaaaaa
    46981 tcagcaattt aagttttgca tacattaata tagaaagtcc taaattttat attgttgtta
    47041 tttattacat aggagtgttt ttttacatat tttacataga aggaaaagag ataaaggagc
    47101 aagagaatga attacaagga tattataagg aatgtaaaag agaaaaactt tgaaaaaatg
    47161 tatctttttt atggaagaga gtattattta attgagaatg caataaaagc atttaaagat
    47221 agtctaaacg aaggaatgct tgattttaat ttagatataa tagatgggaa ggaaatagtc
    47281 ttaaatcagc ttataagctc tatagaaaca cttccattta tggatgatag aaagatagta
    47341 ataataaaag acttcgaact attaaaagga aagaaaaaga attttacaga tagtgatgag
    47401 aaatacttaa tagagcattt agataatatt ccagacacta caactatagt ttttgttgta
    47461 tatggagatg tagacaaaag aaaatcatta gttaagaaaa taggaaacaa tggaattgtt
    47521 tttgattgtg ataagctttc tgatatggat ttatttaaat ggataaaaaa atcttttgct
    47581 ttaaatgatg ttataataga taattctcaa atcatgtatt ttattgaaca agaaggatac
    47641 agagataaga gcagtgaaaa gacattatct gatttagaaa atgaaataaa taaaataagt
    47701 tcctttgttg gtaaagggaa taatgtaacc aatgacgtaa ttgataaatt atctcaaaaa
    47761 aaagttgaga atgatatatt taaattaatc gattatattg gagaacaaaa tgcttctaat
    47821 gcaatgaaaa tattaaatga tatgatacaa gaaggcgaat ctgtattagg tatattttct
    47881 atgatagcaa gacaatttaa aataattatg caagtaagac agttacaact tgatggatat
    47941 tcaacaaaac ttatagctga taaattaaaa atgcatcaat ttgttgtagg aaaagcatta
    48001 aagcaaacta aaaatttttc tgatgatata attgtggaaa tattaaacta tatattagaa
    48061 agtgattata aaataaaaac aggtcttata agagatactt tagcagttga aatgttggtt
    48121 agtagatact gtaaaagaga agcaatttaa aaaatctata tattaataaa aaataaatag
    48181 caagatatgt tatagttcag agtagatgta agctaaatta agtttgatat acaatcaact
    48241 ataatatgtc taactattta ttttttattg tataaattta caaaataaaa aacccctaca
    48301 taggggttat tatatataag aaatataaac tggtaattaa gcgttcatac cgtttaattt
    48361 ttgagctaat ttagctactt ttctagctgc agcattctta tgtatagttc ctttagaagc
    48421 tacttggtat attctttttt gagcgtattg gaactttgca acagcatcct ctctgtttcc
    48481 agctgcaaca gcatcttcga atcttcttat tgcagttttt atttgagatt ttctaactct
    48541 atttaaagca gttttctttt cgataacact tattcttttc ttagctgatt ttatatttgc
    48601 caccgtgttc acctccctgt atttttttat catattcatc gtcaacatat tagattttaa
    48661 cagaaataaa tctaaaaatc aaggattatt atttatatat tttaataatg ttttttattt
    48721 tgatttttta gactgtaaat tgtgtataaa taatttgcaa tatcttgttt ttaaattggt
    48781 atattttgtg ttttaaatat tttgacatat ataaattaat attttatttt tgtaacaaat
    48841 at
//
LOCUS       DAMJYN010000023        48042 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.023, whole genome shotgun sequence.
ACCESSION   DAMJYN010000023 DAMJYN010000000
VERSION     DAMJYN010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 48042)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48042)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48042
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.023"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            110..919
                     /locus_tag="PC466_001404"
     CDS             110..919
                     /locus_tag="PC466_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF2768794.1"
                     /translation="MKDYYKIGEISKIYGIGRDSLMYYEEIGILRPVRDINGYRMYNI
                     SDIWKLNLIKEFRSLNFPMKKIKEYLDDRSIESTKNILNEELDLIDKKIAEFISHKEN
                     IIKRLSSIESVIQNTKIDEIEVVYIEKRKALELNADIKRDEDFDFLIQKLQKEYEDRF
                     NILGNNNIGSAFSTEAINKGIFNEFKSVFCFLESNEKVYNIVFDEGYYVTLNYTGSNS
                     NNKMYMEKVFKFIEENNYKIIADPIEIYKIDIHETGIVEEFVTEIQVPITK"
     gene            1064..1303
                     /locus_tag="PC466_001405"
     CDS             1064..1303
                     /locus_tag="PC466_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768795.1"
                     /translation="MKCSNCGSVNIEKGILTTGGIYAETIGLKYRGDGKLDKVINKTF
                     PVQSTIYSDLCLDCGEIVRTYIKDNTDRNWCKDKK"
     gene            complement(1491..1667)
                     /locus_tag="PC466_001406"
     CDS             complement(1491..1667)
                     /locus_tag="PC466_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768796.1"
                     /translation="MFRDEMDKCTHMLTAYISSLYDYCDFIDTQLDDFILEYGENVVE
                     SCLHQVMVLVSKYN"
     regulatory      complement(1721..1817)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            complement(2172..2846)
                     /locus_tag="PC466_001407"
     CDS             complement(2172..2846)
                     /locus_tag="PC466_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HDF2768797.1"
                     /translation="MNHHILIQFEYIARIITAGFCGALIGYERKNRLKEAGIRTHFIV
                     ALASALIIIVSKYGFNDIVGTPGIGLDPARVAAQVVSGIGFLGAGLIFIRNQSVSGLT
                     TAAGIWATAGTGLAIGSGLYLVGIVSSIIIVIVQITLHRDRKWMKLPTAEQVSLKISN
                     STDSIEYIEGKFKKSNIEIINMNIKRLDGDWLEVVIYTKLPKGYKKTNLLKLFSDNPL
                     IETLEI"
     gene            complement(3066..3620)
                     /locus_tag="PC466_001408"
     CDS             complement(3066..3620)
                     /locus_tag="PC466_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HDF2768798.1"
                     /translation="MSIALILIDIQNDYFKNGKCELFQSEETAENAKKILLFFRKNNL
                     PVIHIQHISTDKTASFFLPNTHGSEINKIVFPLDNEEIIIKHTPDSFFETDLQSILEK
                     KNITNLVICGMMSHMCIDTSVRTAKKLRYDITLISDACTTKNLSWNNIEINANTVHQV
                     FMASLQNSFADVKNTDKFLSNYHK"
     gene            complement(3698..4063)
                     /locus_tag="PC466_001409"
     CDS             complement(3698..4063)
                     /locus_tag="PC466_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2768799.1"
                     /translation="MKIRAEYTCPLEIVHDIIKGKWKTILIFELRQSNKTFSELQHNI
                     YGINQKMLIQQLKELRDFGIIDKISSAGYPLHVEYFLTNRGKKMLKAVEIMQEIGIEY
                     MLEHGQQEILDNKGICYNK"
     gene            4528..5313
                     /locus_tag="PC466_001410"
     CDS             4528..5313
                     /locus_tag="PC466_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2768800.1"
                     /translation="MIVKIDNTLEKEFWQYVSHEESLNLFIIGYVENYGFSSQYQDIW
                     SQVEDGNITSIILKNKSTLIIYSFKNNFDIGEMKNHIKDLDVESISGKKCVIDRLISK
                     YKDFYEKLDNKFCVLKEIKEIDFSNMKEYKIENAQEKDIDEIGKLLNRSDYKVSKNYI
                     EERKEHLKEGNVRAYFIRNDDTMISTVSTGMETSFLAMVVSVSTDKRYRGKGLASYMV
                     YNLSKELLLEGKVPCLFYNNDVAGKIYHNIGYKEINEWTILFK"
     gene            complement(5684..6862)
                     /locus_tag="PC466_001411"
     CDS             complement(5684..6862)
                     /locus_tag="PC466_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HDF2768801.1"
                     /translation="MKTNKISFNKGLYYLNTNANFNFQLNRIIMWDGGRLEDIQKVSS
                     KIVDSESWKTELMYLAQEAEQDGRTENAIAYYRMSEFFMYDGDPDKISVYKKATTLFY
                     NYYSEYFSNGTVQIFHVPYENITLPVMYAKAQGEVKDVILLHGGNDSYFEEFFFPMLY
                     LASQGFDIYLFEGPGQGGVMRLQGKHFTYQWERPVKTILDYFHLENITIVGASLGGFL
                     APRAAAFEKRIERVVAWSVFPNFLDIIVGSQPIKMQNLLRLLLKLKTKWLVNFIIKQK
                     MKSGDSMVVWGLKHGMYAYEASTPYEYFQKIKYYQIDSIAKNINQDILILGATQDHFI
                     DYRTVGKEIDLLNNVRSLTFRLMTEAEQASNHCNCGNSKLVLDTISNWIMMMKIHDRV
                     "
     gene            complement(6965..7729)
                     /locus_tag="PC466_001412"
     CDS             complement(6965..7729)
                     /locus_tag="PC466_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2768802.1"
                     /translation="MTTICVMIDHIFLDTEYRQPTIHKHLAKHIIISQSGNLSVTFDK
                     GESLQCKGIIIDSNVSHTVSSKDNKMLVFLIDDTSILAQNISQHQLLNHSFFVIDNLI
                     VERIQNIYTACQVKGLSQSYIDFSKQAFRLLNLNYHISSITDSRIQWALNHILKSTHI
                     HNEIFFEICAEVKLSKSRFSHLFKEQMGVSLNSYLALSKLRKAYELLLKSGDITSAAM
                     DAGFSSPSHFSASSKKYLGITASELIGKCKIYFIRQ"
     gene            complement(7918..8742)
                     /gene="pdaA"
                     /locus_tag="PC466_001413"
     CDS             complement(7918..8742)
                     /gene="pdaA"
                     /locus_tag="PC466_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="delta-lactam-biosynthetic de-N-acetylase"
                     /protein_id="HDF2768803.1"
                     /translation="MKKDSLKKYIMIGAFALILFGIASINFKSLDKTKTQISSPTLDT
                     HEYDWYFNPREDGKQPSPIKEADFFKKYGAYYVGNPNEKVIYLSFDAGYESGNTPKLL
                     DTLKKHNAKAQFFVVESYIKSNPELIKRMEKEGHLVCNHSKSHPSMAGITDFEKFKEE
                     ITSVEKAYKDVTGKEMPKYFRPPMGKFSEQSLKYTQDLGYKSIFWSFAYVDWYEKKQP
                     THEFAKNKIYSRTHPGAIVLLHPNSSTNTEILDEVLTHWEKEGYKLKTLDYLNNKK"
     gene            8963..12082
                     /locus_tag="PC466_001414"
     CDS             8963..12082
                     /locus_tag="PC466_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HDF2768804.1"
                     /translation="MDNIISVLNDVVFLDIEVSGLDCLNSEILEVGAVKVKDWKIYTY
                     ESLIKNKFEVPIEVFSVCKNLDKNDLEIANEIELVEDRLVNFVEDSFIICHDLSLKKK
                     FFEYHMPKLKNKFIDLIELAVILEPYHKDYSLEYLKNTLTNCNSKVENRALSDAIDII
                     NIVNCLLVKFNNYEKTTLEPLSFKINSYLKKFNLPTWEWSKFLEEANYDLSNNINIKK
                     EYNIFDSKEEKKKERETLKILNEEEKNYEELLKYKTIWENKEGFTYEYRPGQYELTKT
                     IRELFRNSEDEEKIACIEAPTGIGKSVGYLLPAILEARINKKRLLISTDTKELQIQLI
                     NKDIPNVLDSLGLNGKVSYGYIKGKNNYICIDRLEAYIDDYESQNPTKGEILSLIFLK
                     RLVEGGKYGDIEEINYLVFDNFKEISTHLRNVSCDPNMCRPKKCKKDCLYKNRIEELK
                     EEHITVVNHSLLAKWPYKDEKPLENIIVDEAHNLTEKGYDFFSSIINSKSLRYLLQEI
                     YPYEFIQNSSFIYKKYSRNMRKIKAFDKFYNVLKIGREDKQKIARSINLIIEEIDSIL
                     KFGNCNEYNNVSNYNLRWELNLQIDEIVGKLKKDGIDTEISYRAYSEKIKLSCEKIIK
                     NLVSIIIIIYRNIDDDSIDKEADIYKFGKAKTRDLEDIKIIFEIFLEYDEKDDYARIV
                     EIDKNYNDFEFRVVPLKIADLFEENILSQLEKGIFLSATLSLSESMSYFKNTLGIDRV
                     KNVEKIIEPIFDYKNRVSVVGFSDICEYRNSEFPNEMSKIISNISKITEGHTLALFNS
                     KDRQEKTYEILKKYLHSFNLEIYADKKGIRHLNDLNRKCVVLGSKGCFEGVDIPGDGL
                     VCVTLDKLPNLNPKDPLYFTIMKKYGIDYYTINYPQMTIKVKQAMGRILRSKYDYGCF
                     VIFDVGTNISVLKRLEKDLHDCKISKVNSNEFYTYIRRHLNKSRSLILKSVIFDTIKA
                     LNVDAKMDNNDVDKDIIKKDINENIRQRAVKGEVYHIDIIKKDMKVKYFDRNYLINLD
                     IFMREEDKN"
     gene            12100..12699
                     /locus_tag="PC466_001415"
     CDS             12100..12699
                     /locus_tag="PC466_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease H family protein"
                     /protein_id="HDF2768805.1"
                     /translation="MAKQKFYAVKKGKNIGVYNTWDECKKQVNGFSGAEYKSFSTFQE
                     AKEYIDGSEKLSFQEDKEFIEAYVDGSYEHSVKMYGSGVVILKNNEVIKTYSEKGKEK
                     TLVSMRNVAGEIEASKIAMQYCIDNNVQNLILYFDYEGIEKWCTGVWKTNKEGTIAYK
                     NFYDSIKNKLNVKFTKVKAHSGNKYNEEADKLAKKAIGV"
     gene            complement(12956..15085)
                     /locus_tag="PC466_001416"
     CDS             complement(12956..15085)
                     /locus_tag="PC466_001416"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HDF2768806.1"
                     /translation="MPNLPSLGSKAPDFKANTTNGPIRLSDYKGNWIVLFSHPGDFTP
                     VCTTEFLCFAKYYDEFKKRNTELIGLSVDSNSSHLAWMYNISLLTGVEIPFPIIEDRD
                     MRIAKLYGMISKPMSDTSTVRSVFIIDNNQILRTILYYPLTTGRNIPEILRIVDALQT
                     SDRDNIVTPANWFPGMPVILPYPKNYKELKNRVNSCNKKYSCMDWYLCFVPDNYNDEE
                     VSKKIDNTCSWKKEHTKNIENECNCEHEHHDYLNKALDCKQEHKTDIKDDCNHEKKHT
                     KNTNKVHNSKQDKFKDKSCDEMNFNYDKDESCDKINSSYNKEDSSYEDFYKHNYKNYD
                     YTSEKNTKKIAMKTLKDSKKLVRPQITDPYNPIVENANCPDINPIVAEYVLGNPTNVD
                     AQLLDAVIFAFAEIDQSGNLFIPYPRFLNQLLALKGEKPSLKVIVAIGGWGAEGFSDA
                     ALTPTSRYNFARQVNQMINEYALDGIDIDWEYPGSSASGITSRPQDRENFTLLLTAIR
                     DVIGDDKWLSVAGTGDRGYINSSAEIDKIAPIIDYFNLMSYDFTAGETGPNGRKHQAN
                     LFDSDLSLPGYSVDAMVRNLENAGMPSEKILLGIPFYGRLGATITRTYDELRRDYINK
                     NGYEYRFDNTAQVPYLVKDGDFAMSYDDALSIFLKTQYVLRNCLGGVFSWTSTYDQAN
                     ILARTMSIGINDPEVLKEELEGIYGQF"
     gene            15351..15599
                     /locus_tag="PC466_001417"
     CDS             15351..15599
                     /locus_tag="PC466_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768807.1"
                     /translation="MMICFAMTFALVLINSVMGVHIGLDYYFLMGSVLTVCLTIGIVL
                     CNARKIFDSKAIHKTRTKTVSTNKKQKSHSRDIKRKIS"
     gene            15765..17156
                     /locus_tag="PC466_001418"
     CDS             15765..17156
                     /locus_tag="PC466_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HDF2768808.1"
                     /translation="MNFRDLFEKAVDFIDEKRKSIVAISLSTLGVIALIIVFFLSSNE
                     FSVGNEANELLKIIEKRQYSIAVDYYTSIEKKFSDSKMERFNKSVSKKINKLLLNSGD
                     KYLDGDISQESFIGLINTVKELNKISIDVDDLLAQADRVREMYKEENTTYDIAINYIS
                     TVSILNGMGSNLDVYKQNIETIKESRDVYDSAVKDQKAYKYYEAIEKYNKVLKEDEKY
                     YSMAQNGKEQCIEEMYDYYISRAEEANTSGDYERALQYIEYLKEDYSDDEKVQSLEKK
                     YKKNLSLYTLTSDDIINVIAKKSGKDKANLSINSLPQMIKNNKYYYAEVYEYDKLINE
                     VLVSAKTKDLYSYKDGKKDYKVDYGDGYFRILEDGSYQFGITKDKAKFVLTNTLDEKE
                     NKYKKIEILDIEKADRYVKSKKSLEELFGKYKNIYYYAVVNKGLFRGKEVYAINIYNE
                     KIYAISENGLNEY"
     gene            17271..18740
                     /locus_tag="PC466_001419"
     CDS             17271..18740
                     /locus_tag="PC466_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanW family protein"
                     /protein_id="HDF2768809.1"
                     /translation="MSNVNKKLVIAIGAVALVAIIFIGIMCMQFKGEKIAKNTYVNGV
                     DIGKLTKSQAKQELAKKYKLENVEFNYNDKSWKVKSKDLNLSTDLDKTVENAYNLNRK
                     SSFFGNLSKTISTNFGKKSNLVVVINYDKNKLKAEMEKIAKEIDVDVKDATLDISGEK
                     VKVIPDSDGLKMDISKSMENFDNQTKKGNYKNELVVKATPAKVKKEQLTNIDTNLGTY
                     STIFKTSQINRSINIKLATDNISNVLLMPGETFSFNKHTGKRSKENGYKSAPVIMEGE
                     MEEDYGGGVCQVSSTLYNSVLYAGLEIVNVKNHTIPSSYVPKGRDATVADSGIDFLFK
                     NNLKHPVYIKNYVSGNQIVCNIYGSAEDKQNITISTKLDGVSQTTMKRVNDPTMPKGK
                     EKVDKSGRNAYSVSTYRTFNDANGKKIKTEKIANSYYPKKEGIILVGTMEPKPEEKPN
                     TDENKNNQNTNNQNPNNQQKPETPPTDNKPNETQPQPQA"
     gene            18805..19398
                     /locus_tag="PC466_001420"
     CDS             18805..19398
                     /locus_tag="PC466_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fis family transcriptional regulator"
                     /protein_id="HDF2768810.1"
                     /translation="MNLNNITNYVQSICENISNVLDVDVTLVTKDLTRIAGTGIFRGK
                     IGETISEKSVYSLVLKDGKSYVINKEIEENCNKCANRENCKELADICTPVKMGEHILG
                     ILGIAAFNEEQKEKILSKDKELTAFVRSMSDLISFKLDELYKQEVKTIDDLEREAIEN
                     AIKKYGSNTEGMKKVAEALNIGIATLYRKVKKFNIKS"
     gene            19580..20926
                     /locus_tag="PC466_001421"
     CDS             19580..20926
                     /locus_tag="PC466_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HDF2768811.1"
                     /translation="MPRKILDISLIEDNKSDLTFFNIEEEDGDETLKALKQSYVTTNY
                     KEETLLNLQGALNSKSDTTSKELKLESYKRYNNALDLAYKNYITSAINMVNKALEINP
                     KDIDILNLRGLLKLLKCDFAKSFESFYTALCYENNHISRKYVNLISSEDFKTFLGRYN
                     HSIRFINEELNYESIHILENIIEEEPELIEPYVILSLLYDKLGNVKKREGYLDKLKEL
                     DKDNPVFEKNEEEKEDTSKKEEIRKVKRKKSILPYIIVGCVLIGMGIYLIQSKKRIEN
                     LNNQISSKEEKLSETDKKLGETSKKLEKTNKELNEVKNKEPEREITVADEEDLYYQAL
                     NLKKNKEYEKAIDNFKSVVSSGKTKKYISESIYQLAITNKLLGNKDEAIKYYKKYINT
                     YTKNDQYYDDSYYELGMLYYDNGDLKNAQQTFYSLRSEVPDSMYNNSKIKEILSEK"
     gene            21108..21479
                     /locus_tag="PC466_001422"
     CDS             21108..21479
                     /locus_tag="PC466_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HDF2768812.1"
                     /translation="MKVFNQLVIILSIWVIGEYISSFIQGIILIPGSIVGMLLLFLLL
                     QFKVLDLSSIENVSGFFLDNMAIFFIPAGVSLIKSLDLIRENVLVLLLVICLSTLIVM
                     YTTGIIVEKMIKKKEEGQKNV"
     gene            21472..22161
                     /locus_tag="PC466_001423"
     CDS             21472..22161
                     /locus_tag="PC466_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HDF2768813.1"
                     /translation="MYNVLQTPVFGIIVTIVFFNLGRYIQRKTSNPICNPLLIAIVGI
                     ILFLSISKIPYENYKIGADSLNFFLGPVTVVLAVPLYKQFELFKKHMFEIIVGIGCGI
                     VISFVSVLIIGKIANSDVSIINSLIPKSITTPMGISLANSLNGIESITVVAIIFTGIF
                     GGMVASTVFKLGNINHPVAKGIALGTSAHALGTTKAFELGEIEGAMSGVSIGVSGTIT
                     VILIPIIMNFI"
     gene            22681..23547
                     /locus_tag="PC466_001424"
     CDS             22681..23547
                     /locus_tag="PC466_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HDF2768814.1"
                     /translation="MSEVKNTLQKHPVLRYSTMLFGMLMTSIGINGFLRPAHLLSGGA
                     TGIATSINYLTNINVGLLTFLINIPIFILGFIYLEKEFCISSLVNMIVFSLLLGATQE
                     ISNIIPIHDILLQSVYGGILSGLGVGVVFRTRSSQGGTDIIAAILKIKKNIEMKDTAL
                     AINGLIVLTGSFLFGLDLALYTLIGLFLNAYSMSFIKDAMNYQKSVMVMSNEVDLIAE
                     DIMKSLVRGVTFLDAEGAYTHQKKKIIYTIVSSNEIPKIKDIALKYDKKAFISVNDVT
                     EVKGRGFKAKDL"
     gene            23789..24598
                     /locus_tag="PC466_001425"
     CDS             23789..24598
                     /locus_tag="PC466_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768815.1"
                     /translation="MNLSKEYVNLYDNYLKYINEVNKEIRSIKNMKKRVLKKGDFAPE
                     NEVLELEGKTIRDIDDVDTKKPKNKIYKFSNGDVYVGKFLEGKMEGQGSYTFFVDEGT
                     AMEYIGEFKEDKKNGKGNFVFSNGNEYIGHFEEDMMNGIGNMLYNSKDEYIGTWKNGK
                     KDGKGIYKWSDGCIYAGEFKGGKMEGYGICYNSKGEVLYEGEWKNNLIHGKGTYIWEK
                     GKKYIGEFMHGKKHGQGTFYLNNELVYEGTWKFDKPSIFDRTLDEIFSLRL"
     gene            24741..25805
                     /locus_tag="PC466_001426"
     CDS             24741..25805
                     /locus_tag="PC466_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HDF2768816.1"
                     /translation="MKRLIALVLVILIVLFYSPELIEEGYDLKEKFFQSEIWNEFLDK
                     ININNNSKKDKKEQNQNLQSNNTEGENLGESDIKNFEKISLGDNLSYVLSSIGKPGRI
                     DISEYGFDWYVYNQYGKEFAMVGLENDEVVALYSNSINSCENQDIKLNQDRQTVRTKI
                     TPLKYKRKGNTRYIINSENQYDIISKEGKYITIFYDIHEENRVCSYLIIDKSTEDEFK
                     KLYPDDREELKKCFELEVIDLVNSVRNQRGLNSLRYSEQATLSSRKHSEDMRDNNFFD
                     HINKKNETPFDRMKREGIVYTSAGENIAAGQINAIYAHEAWMNSEGHRKNILGNYNNI
                     GVGVIFGGSYKTYYTQNFYK"
     gene            25833..26552
                     /locus_tag="PC466_001427"
     CDS             25833..26552
                     /locus_tag="PC466_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HDF2768817.1"
                     /translation="MTSWKKKTVYKCLIAVVLFCGIVLISNFSKVSALMMDTNGNVLI
                     KHGSREKKLIAITFDDGPHPKETSQVLDVLKKYNVKATFFIAGKHAKWYKEPLVRASK
                     EGHEIGNHTFNHPDISNLSSSQIEEEIVKCEDILKEVTGKKPTLFRPPFGSYREKDLI
                     EIAKKHDYKVVLWTGVDVKDWKNPGANSIADKIINKVKNGDIILLHDYATNDTVEALD
                     MFIPKMIEKGFKFVTVSELIK"
     gene            26576..27160
                     /locus_tag="PC466_001428"
     CDS             26576..27160
                     /locus_tag="PC466_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HDF2768818.1"
                     /translation="MILMIDNYDSFVYNLVQYIEELGEAVVVKRNNEIKISDIEELNP
                     EVIVLSPGPCSPKEAGICIDIVEHFKGKKPILGICLGHQTIGYVFGGDIIKAQQPVHG
                     KVYSINHTNKGVFRGLKNPLNVTRYHSLIIDSNTVPKELEITAITDKGEIMGIRHKKY
                     LIEGVQFHPEAILSEYGHEMLENFITEARERVHM"
     gene            27162..28511
                     /gene="pabB"
                     /locus_tag="PC466_001429"
     CDS             27162..28511
                     /gene="pabB"
                     /locus_tag="PC466_001429"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HDF2768819.1"
                     /translation="MIREINTKLNSFEIFTIFRNEHDSFILDSAMDKEKLGRYSFISS
                     QPFKVLKYKDTDENPLEVLKEELHKYRVVNDTNLPFVGGAVGYLSYDLGNYIENLPRT
                     AVDDIEMPDMYFGFYNHVIVIDHLVQKTYIATPNIDIELEEKIIDDIEQRILKEEKKG
                     IDSICYEEKEVTPIRLKSNFTKEEFKNAVQSVREYIRQGDIYQANLTQRFSGETELTS
                     FELYRDLRRFSPAPFGAFLNFEDTHILSNSPERFIRCVNKRIETRPIKGTRPRGKDKE
                     EDLRLQQELRNSEKDRAELLMIVDLERNDIGRISKTGSVKVPELFVIEPYANVNHLVS
                     TVVGELKDDKDATDVIKATFPGGSITGAPKIRAMEIIDELEPTQRNVYTGSIGYIGFN
                     GDMDFNIAIRTIIKNDKKVYFQVGGGMTWDSDPDEEYQETLDKAKSIMKALRGYYEE"
     gene            28501..29244
                     /locus_tag="PC466_001430"
     CDS             28501..29244
                     /locus_tag="PC466_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class IV"
                     /protein_id="HDF2768820.1"
                     /translation="MKNNVGFDSSLSKFGIGLFETIRVKNGIAVDLDIHIERMLSSIN
                     CLDLDINYKKDFLINEIVTYIKKENVINKALRITVFDEGYNISIRDIPYNQETYEKGF
                     KLAISPIVRGNSLIHRHKTTNYFENIYTKNIANKTGYNDGIFLNSEGVILECSMSNIF
                     FIKGERVYTPSDRLPILNGIIKKRIIEICDELHIELIENEINISEISSFDFVFVTNSL
                     MGAIKVTEIDKIKFNKENVVFDKIVKLLE"
     gene            29278..29979
                     /locus_tag="PC466_001431"
     CDS             29278..29979
                     /locus_tag="PC466_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768821.1"
                     /translation="MIGCIYEVYNEEMTKIIENQNTLAVYLVGSSKDVDFTLYDVEIN
                     DIDVFVFVKEGEKQERILFKKKGIEFDVNYFSKDGVKKLLSNREYFFVKEMKDAKVLF
                     DRENISNIIKDISRDIYLEGPSKMSLEEKSFIKQDIGAKISNLKNKEKFDVFEYHFLT
                     NLYLKDIIIGYFNINDKWVPKDKKLLKVLKKENNELFELASKVSENYDYQRLLDVYNY
                     IFKEIETKEVIKLIF"
     gene            30005..30577
                     /gene="folE"
                     /locus_tag="PC466_001432"
     CDS             30005..30577
                     /gene="folE"
                     /locus_tag="PC466_001432"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HDF2768822.1"
                     /translation="MNKVDKEKIQHAVREILEAIGEDPDREGLIETPNRVARMYEEIF
                     SGLSEEPRDHLKVLFADEKHEELVLVKDIPFYSCCEHHLVPFFGKAHIAYLPKGGRLT
                     GLSKLARVIDTLAKRPQLQERITKNAADIIMEELQPYGVLVVVEAEHMCMTMRGVKKP
                     GSKTVTSAVRGIFEKDIASRAEAMSLITMK"
     gene            30643..31434
                     /gene="folP"
                     /locus_tag="PC466_001433"
     CDS             30643..31434
                     /gene="folP"
                     /locus_tag="PC466_001433"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HDF2768823.1"
                     /translation="MFDYGKRTYIMGILNVTPDSFSDGGDFNNLDIAIQHAKDMVDQG
                     ADIIDLGGESTRPGHSYVDSDEELRRVIPVIKKLKQELEIPISIDTYKADVAEEALKL
                     GVTMVNDVWGLRKDKNMASVIGKYDAEVCIMHNQDGTNYDKDIMESIKDFFKVSIEMA
                     MSCGVKKEKIVLDPGVGFGKDFEQNIEVLRRLNELKDLGYPILLGTSRKSVIGKVLPV
                     EPKKRLEGTIATTVLGIRDGVDIVRVHDVYENLMAARMTDAIYRK"
     gene            31445..31810
                     /gene="folB"
                     /locus_tag="PC466_001434"
     CDS             31445..31810
                     /gene="folB"
                     /locus_tag="PC466_001434"
                     /EC_number="4.1.2.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin aldolase"
                     /protein_id="HDF2768824.1"
                     /translation="MDKILLSNLGFYGYHGVLKEENFLGQKFFVDMELYIDSREAGLS
                     DDINKSVSYAEVYNVVKDITENKQFNLLEALAENIAEEVLNKFILINGVMVRVRKPEA
                     PVNGIYDYFGVEIRRTRDE"
     gene            31803..32309
                     /gene="folK"
                     /locus_tag="PC466_001435"
     CDS             31803..32309
                     /gene="folK"
                     /locus_tag="PC466_001435"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HDF2768825.1"
                     /translation="MNKAYLGIGTNMGDRFDNLSRACELLKNSDSIYKVKESSLYETK
                     PWGYTEQADFLNMCVEIETEFEPYELLEYCQEIERELHRERIVHWGPRTIDVDILFFN
                     DVASTDERLTIPHPRIQDRAFVLIPLMDLNEELIINEKTVKEHLNLLSAEEREEVKEL
                     VGYERKPI"
     gene            32290..33075
                     /gene="aroF"
                     /locus_tag="PC466_001436"
     CDS             32290..33075
                     /gene="aroF"
                     /locus_tag="PC466_001436"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HDF2768826.1"
                     /translation="MKENLFNNNSKIEINTNNKKITVKKDKLIIAGPCAIESYEQLLE
                     TAKFVKSQGANILRGGAYKPRTSPNSFQGLKKEGLKILKAVKDEVGMAVITELMDVRD
                     IDELYSISDIIQIGSRNMQNFTLLSEVGKQNKPVMLKRGIASTITEWIGASEYIAIEG
                     NSNIIMCERGIRTYNDYTRNTLDLAAVPIIQKETGLPVVVDPSHATGVRYLVKPMSLA
                     SFACGADGIMVEVHPDPENALSDGAQSLCFNEFEDLMKSINNY"
     gene            33330..35120
                     /locus_tag="PC466_001437"
     CDS             33330..35120
                     /locus_tag="PC466_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HDF2768827.1"
                     /translation="MNDIKDIIEEIKARCDIASIISEYMNIKQSGANYKGLCPFHGEK
                     TPSFYINTSKQIYKCFGCGEGGDVINFVMKMENLDFMDAVKILANKCGIEINTNMNEE
                     TRIKIEKSKKFQDIHTEAARFYLSNLLGSKNLGYEYLRIRGLDDKIIKKFGLGFSLDS
                     WNSLMNTLISKGYKKQDLLDCGLIAKNRDGTNCYDKFRNRVMFPIFDYRGNIIGFGGR
                     VLDDSLPKYLNSPDTLIFNKKQNLYGLNFARKNLESKTIVLVEGYMDLISLYQYGIKN
                     VVATLGTALTEQQGILIKRYADTAIISYDSDEAGIKATLRAIDILTKLGINVKVLDLK
                     DAKDPDEFVRKYGLSDYKKAMDVSTHYIKYKIDHLKKEFNIQKDEERVKFAKEASKII
                     KQLTSPVEIDFYTKYLSNQIDINVESIKREVYGKNYNKPYNNKNQKKIEEKVIEKVEV
                     RQDGKQLVEETLIKIMLEDKKIREIALLKVEESDFLLKESKEILNYMIKNQELDKITI
                     DKLKSLNISEEYLKELNSISLNSINLENTKEIEGIITNIRKNSLEEQINSLLREQQEL
                     ENNNDMKEVDGRVMEIALKIVEINKILKSL"
     gene            35138..36304
                     /gene="rpoD"
                     /locus_tag="PC466_001438"
     CDS             35138..36304
                     /gene="rpoD"
                     /locus_tag="PC466_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HDF2768828.1"
                     /translation="MENKSNKKELKKVTAKTLIEKGKKQGSLTLAEIMEAFSETELDK
                     DQVENLYETLGNLGIEITETKNYKADIDFSVADDDLSIGHLDEDAEAISHDDSSAIEI
                     ETVDLSLPKGISIDDPVRMYLKEIGKIPLLKPHEEVEFARRMHEGDEIAKQRLVEANL
                     RLVVSIAKRYVGRGMLFLDLIQEGNLGLIKAVEKFDYTKGYKFSTYATWWIRQAITRA
                     IADQARTIRIPVHMVETINKLIRVSRQLLQELGRDPKPEEIAKEMEMTEDKVREIMKI
                     AQDPVSLETPIGEEEDSHLGDFIPDDDAPAPAEAAAYSLLKEQIEDVLGSLNDREQKV
                     LKLRFGLEDGRARTLEEVGKEFDVTRERIRQIEAKALRKLRHPSRSKKLRDYLD"
     gene            36469..37158
                     /locus_tag="PC466_001439"
     CDS             36469..37158
                     /locus_tag="PC466_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HDF2768829.1"
                     /translation="MKLTDRLLKIASLVSDGKKIADIGTDHGYIPVYLLKEGKVPFAV
                     LADVNKGPLDNAHKEVIQNNLLDKVDLRLGSGIEILEIGEVEEVIIAGMGGILISELL
                     EAKKEVAHNVEKLILQPMQAQEELRYYLLNNGYEILEEVLVREDFRIYEIIVAKYTGK
                     NTIIEDEIYYEVGIKLLENKDSLFNDFIEKKIKTYSSIVNKLEGKNGEAIDKKRKESE
                     VAIKKLENLIK"
     gene            37172..38269
                     /locus_tag="PC466_001440"
     CDS             37172..38269
                     /locus_tag="PC466_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HDF2768830.1"
                     /translation="MLLKSLTRKIEKKYPLNLAEDWDNVGLIVGDFDMDVKKVLVSLE
                     ANEDVIDEAISKNIDLIVTHHPFIFGKINKINSGDLKGRLIQKLIKNDISLYSMHTNF
                     DIAFDGLNDYFMEIMEFGNSKVLDITKSENLYKLAVYVPHNYSDELRKVLSNSGAGHI
                     GNYSDCTFSIEGEGQFKPLEGSNPFLGSVNDIETVNEVKIETVVPQKLLGGVISSMLD
                     AHPYEEVAYDLYKLENKGEIFGLGRISKLDKSMTLESLSRKIKEKLNMKHIRVVGNLS
                     TDITKVAVVTGAGSEFVKKAKRQGAEVLITGDVKYHEAQDALDIGMCIVDCGHFDTED
                     IFKNVMKRFLDEFSEIEVIKSNVYLNPFSTI"
     gene            38331..38903
                     /locus_tag="PC466_001441"
     CDS             38331..38903
                     /locus_tag="PC466_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HDF2768831.1"
                     /translation="MKVAVIFHSVCGSTYLLAREYKEVLEEMNIEVDIFRVSDEVAKT
                     LPQYYLINYKEYKDEFESINVIKSGKEILDYDAIFMGSPTYYGNVSGPMKMFMDSFSD
                     IWVGAPLSGKIFGCFATAGSQHGGGELALQAMNIFAQHMGMTLLSVPCSVRGGYPAYG
                     ILHIAGDNSDIRPNDDAKIGIRDYLKRLNI"
     gene            complement(38963..39430)
                     /locus_tag="PC466_001442"
     CDS             complement(38963..39430)
                     /locus_tag="PC466_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HDF2768832.1"
                     /translation="MFKEMRLKKREMTKEDTVEVLKNGEFGTFSTISENGYPYGVAVN
                     YVYFNDSIYFHCARNGHKLDNISKNNKVSFLVVANESVIPDKFSTTYSSAIVFGKACT
                     VENEEKKNALVEIIKKYSKGFFEEGMKYIEKDMNLTTVVKIEIDHISGKASRI"
     gene            complement(39816..40292)
                     /locus_tag="PC466_001443"
     CDS             complement(39816..40292)
                     /locus_tag="PC466_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HDF2768833.1"
                     /translation="MLSKAEIKYFNECASEILSSEKVQLMRTFPHHGNVSCLEHSLSV
                     AYYSYLLCKKLHLRVDIQSVIRGALLHDFFLYDWHYKGDRKGLHGFTHPREALKNATL
                     FFQINEKETDIILKHMWPLTVKPPRYKEAFIVCLLDKFCCLVETLKIHSLLSPYHV"
     gene            complement(40412..41503)
                     /locus_tag="PC466_001444"
     CDS             complement(40412..41503)
                     /locus_tag="PC466_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1648 domain-containing protein"
                     /protein_id="HDF2768834.1"
                     /translation="MSKIECLFTIFPVLILMYATFYFMPYFVGKKHIYGVSIDQEHKN
                     YNYFIKLDKEFKKLLSLGFIIDFILVFILVFTFNKLELSYFIGIIGFLLYESILYIHT
                     HKKAKKLKSEIYSKLGHIDVDSKLIVDMDFINKKNKIIKKFKIIYLIPILFTLGMSIF
                     IAFNYNKLPDSIATHWNINGSPDVFIDKSFLNVFKLIGTDFCLMVLLYITSIGSIKSR
                     IKIDTNRIEESRVENIKYLNKIGYLFLILMIIMTTQFFTTLLSIKTKLSTAMNITTLL
                     VIIYLIATYINSPNLKFNSSYSPEEDEKYWIAGIMYNNPNDPSLMVNKRFGIGWTINF
                     GNPLGKILYIAIALLLIFSLFSLIKSLLL"
     gene            complement(41496..41885)
                     /locus_tag="PC466_001445"
     CDS             complement(41496..41885)
                     /locus_tag="PC466_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2768835.1"
                     /translation="MVLNLDFNSDKSIYVQIKEEITKAIASGELKINESLPSVRSMAE
                     NIGVNLHTVNKSYNELKEEGFLNIDRRKGAIVAQLPMKIDNTTRQKNKLDLELLVAKS
                     YLSGISKEEFLSLSSSLFDKYEVKYYE"
     gene            42077..42523
                     /locus_tag="PC466_001446"
     CDS             42077..42523
                     /locus_tag="PC466_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768836.1"
                     /translation="MLTYLMKRQMHKKDDGMSKPMMITGAVITGVGAYAVYKMVKSHK
                     SNSQMVNTNYYGNSDYDDYKYDEFDYDCDCRDTKQDYEYEELKKKVKEFNSRRINCEN
                     CPHVSQEEMMQYVNSVKDVKEDIDLHEDAKKDNIYKEDEYKKYEEE"
     gene            42787..43512
                     /locus_tag="PC466_001447"
     CDS             42787..43512
                     /locus_tag="PC466_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2768837.1"
                     /translation="MKRKEIVMLKLLIVEDDSTISFGIKYALEQEGFSIDISKDLSSG
                     KEMISSNEYSMILLDVTLPDGTGYELCKYIRGFSQVPIIFLTACDEEVNIVMGLDIGG
                     DDYITKPFRIRELISRIKAVLRRKGNTSEENKKILKFGDLSIYTLEARVYKNDKEIFL
                     TSVEYKLLLILIQNKNTVLSRTQILEKLWDVTYDFVNDNTLTVYIKRLREKIGDDLCE
                     PIYIETVRGIGYKWIGSENSVSI"
     gene            43499..44743
                     /locus_tag="PC466_001448"
     CDS             43499..44743
                     /locus_tag="PC466_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2768838.1"
                     /translation="MFLYNPEVKKFLSKYVTLMFIVIIISIGFSIINVSLTKEMVVRN
                     NQAIIGTLSSKYPNLESQIVDIITQGKSMKNIDYGQKILSKYNYDKSIKINSEPIISK
                     LVLETIKINIILVCIIFILIFVLVVRYFTSIYNDLSDMTKYVYYSSEGKPFDMKNKNQ
                     EGQIGLLKTELLKMTTILNEKVELLKREKIFLNNTISDISHQLKTPMTSLIMLNDLLY
                     NDVPYEVKIDFLNKIKNQLNRMDWLIKSMLKLSKVEAKVINFKKDKVKFSELIHRAML
                     SMKIPMEIKNQKLTIEGNDNVSYIGDIDWSVEALVNIIKNCVEHTPEFGNIIITYKEN
                     PLFSELIIKDEGEGIDKKDIPHVFKRFYRGRSSSKEDSVGIGLAMSKSIIESQNGDIY
                     VNSEKGKGTEFHIIFHKMYDSD"
     gene            44823..45500
                     /locus_tag="PC466_001449"
     CDS             44823..45500
                     /locus_tag="PC466_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003517588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2768839.1"
                     /translation="MEILRVENLTKSYGKNETKVDAIKNVSLSVEKGTFIAITGPSGS
                     GKSTLLHLLGGVDRPTSGKVYINDVDIYNLKTKDLAIFRRRNIGLIYQFYNLIPVLNV
                     KENILLPAELDNRDIDREYFDDLMKTLGLIDREKHLPNQLSGGQQQRTSIGRALINRP
                     SIILADEPTGNLDSKNSKEILELLKLSVKKYNQTLIMITHDKNMALQADRIISIEDGI
                     IKSDEVM"
     gene            45501..>48042
                     /locus_tag="PC466_001450"
     CDS             45501..>48042
                     /locus_tag="PC466_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2768840.1"
                     /translation="MNLYTSLTIRYLKQNKRRTIVTIIGIILSTALICGIGNIFESFM
                     DYQMRETIKNDGSFHVTFYDVNRKNVEYVTKSAEIEKHAFTKQLGYSKLENSENAILS
                     IKQYDQNAINGYKVSIKEGRFPAKEGEIVLSESIINLIDDKLKIGDKITLKVGDMFDS
                     SKKKIDSMTFHEGDYIANEKDRTFKVVGIIKKPGFERYNGIATAIAYFNPMNNYNDTI
                     NVSVAVRNPKDVYKISNKISKNIYSNKDKEAVSDMIKYNEHLLRLQGASKYSNINSSI
                     KSIIIAVTILVIICTIATVYNSFSISINERKKQFGILNSIGATSSQIKRLVFIEGIII
                     SLIGIPIGLISGTVAIDLLFKIINKYFTESVVTKMSLQIVYNPIIIIVSIIIVLLTIF
                     ISILLPAISASNISPLNVIKNTGEYKVGKIKSSRLIKMIFKTEGVLAYKNIRRNRKKF
                     IITLFSLMVSIIIFISFSGFTLLLLRGEEIRNSQRKYDLYLTAKNTARSVEDTISELE
                     DIDGIKNFELATGQYVSIRVSENKINKSKEDLIRKYYQKYKIGESYEYDFSNNELIFP
                     GDFAVKNKINNLVQGSFNKERAIEENGVILVRKSAIEENGKKGVVELTNYKVGDTVNC
                     EYLDENALSKKVKVKILAITDEERLGFGYQNMGLQFITYDEVAKNLNLKLSKSLIFID
                     SGGSIKTKKEIEALANKNDFNFYDEISSSESEKQDLKVIKIFVYGFIVVISLVSVTNI
                     LNTVSTSINLRKRELAVIQSIGVTPKGFRKMIYLESFIYGILSLLFGIPISIGIILIM
                     NKLISGVIEFSPIIPWTAIVICIVSVFIITFIAGYIPMSKLNKENIIDN"
BASE COUNT        19293 a         5053 c         8058 g        15638 t
ORIGIN      
        1 cctatccttg ttttaaagat ttttttagta tattctaata ttatagtatt atagagtaat
       61 aatgttgatt taaaataaaa ataggatttc ggaggagttt attatataaa tgaaagatta
      121 ctataaaata ggagagatat ctaaaatata tggaataggt agagattcat taatgtatta
      181 tgaagaaata ggcattctaa gaccagttag agatataaat ggatatagaa tgtataatat
      241 atcagatata tggaaattaa atttaataaa agaatttaga agcttgaact ttccaatgaa
      301 gaaaataaaa gaatacctag atgacagaag tatagagtct acgaaaaata ttttaaatga
      361 agaactcgat ttaattgata aaaaaatagc tgaatttata agccataagg aaaatattat
      421 aaaaagattg agttcgattg aaagtgtaat tcaaaataca aaaatagatg agatagaggt
      481 tgtatatata gaaaaaagaa aagctttaga attaaatgct gatataaaga gggatgaaga
      541 cttcgatttt ttaattcaga aacttcagaa agaatatgaa gatagattta atatacttgg
      601 aaacaacaat attggttctg ccttttctac tgaagcaatt aataaaggta tatttaatga
      661 gtttaaatct gtattttgtt ttctggaaag taatgagaaa gtatataata tagtttttga
      721 tgaaggatat tatgtaactt taaattatac tgggagtaat tctaataata agatgtatat
      781 ggagaaggtg tttaaattta tagaagaaaa taattataag ataattgctg accctataga
      841 aatctataag atagatatac atgagactgg aattgtagaa gagtttgtaa cggaaattca
      901 agttcctata actaaatagc catatttcaa tggattagat ggtaaataga atgaaaaaat
      961 gttgatttgc caccgatttg ctactgtgtt ataaaatcgg tagcaaatta tattttaaat
     1021 tataagatag catgaaaaaa taattgttta gggggttata aatgtgaaat gttctaattg
     1081 tggaagtgta aatattgaaa agggtatttt aacaactggt ggcatatatg ctgaaactat
     1141 tggattaaaa tatagaggag atggaaaatt agataaagtt ataaataaaa cttttccagt
     1201 acaatctact atatattcag atttatgttt agattgtggc gaaatagtta gaacctatat
     1261 aaaggataat actgatagga attggtgtaa agataagaaa tagaataatt tttgaagtat
     1321 attaatattt gaagttgaat tttattaaag atacaagtga aaaagtataa atgggaagaa
     1381 attgttatat ggaagaaaac tttgcatata ggggagatta gttttttaat ataataacat
     1441 ttttaaatgt agataaaact aaaaagggtt ctctagaaaa caatttctat ttaattatac
     1501 ttacttacca ataccatcac ttgatgtaaa caagattcta ctacattttc tccgtactct
     1561 agtataaaat catctagctg tgtatctata aaatcacaat aatcatataa actactaata
     1621 taagcagtta acatgtgtgt acatttatcc atttcatctc taaacatata tattactatc
     1681 cccctaaaaa actttcataa aacaaaaaga acaatatctt tttggcaact ggctgacata
     1741 actcatagtt tattttataa gcgttagtcc ctatagcttt gcgtcactaa atttctctag
     1801 ttttgccgat ttagttttat tctacaacta aaataataca ctaggataag ttattgttca
     1861 acatacttgt cagaaaattg aaatatttaa cagtatctta acaatatgaa atctattttt
     1921 cactcaagaa acaaactata catgtagaat atttaataaa aattatattt agttttgtat
     1981 tgaagttttt gtattaaaaa gtttagttca caagagttac ttggctagat aatagatgag
     2041 caaaaatatc ttgaaaaaat atatatgaat ggcaaaaaac aagggatgaa ttttatatag
     2101 actcatcccg taattattta tatattgacc ttgattaaat atattattat ttttaagctt
     2161 caatttttat attatatttc taaagtttct ataagaggat tatcgctaaa taattttaat
     2221 aaatttgttt ttttatatcc tttaggtaac ttagtatata taactacttc taaccaatcc
     2281 ccatcaaggc gtttaatatt catgtttata atttcaatat tagatttttt aaatttacct
     2341 tcaatatatt ctatggaatc agtgctgtta gaaattttaa gagaaacttg ctctgctgta
     2401 gggagtttca tccacttcct atctctatga agtgttatct gtacaataac aataatgata
     2461 cttgaaacaa taccaactaa gtataatcca gagccaatgg caagacctgt accggctgtt
     2521 gcccatatac cagcagctgt agtaagacca cttactgatt gatttctaat aaatattaat
     2581 ccagcaccta aaaaacctat accactgaca acttgtgctg caacgcgggc tgggtctaga
     2641 ccaatacctg gagtacccac tatatcatta aatccatact tggaaacaat gattataagt
     2701 gctgaagcta atgccactat aaaatgagtg cgtattccag cttcttttag tctattcttt
     2761 ctctcatatc caattaaagc cccacagaaa ccagcagtaa tgattcttgc tatatattca
     2821 aattgaatca atatatgatg gttcatttat ctagcacccc cttctatata atattatata
     2881 tactataata ctacattttt tatgtgaata tagtaaagtt taaaatttat ataatagtta
     2941 tatatgaata taaaatgtat aaacgtatat tatgtatata aaaatgatag aaagcatcta
     3001 attttaaatg attaaagagc aagcttaaat aaatcaaact tgctctttta acatagtgta
     3061 tgtttttatt tgtgatagtt agataaaaat ttatctgtgt tttttacatc tgcaaaactg
     3121 ttctgtagtg atgccatgaa tacttgatgt acagtatttg cattaatttc tatattattc
     3181 caagataaat tcttcgttgt acatgcatcg cttattagag ttatgtcgta tcgaagtttc
     3241 tttgctgttc ttacacttgt atcaatacac atatggctca tcattccaca gattactaga
     3301 ttagtaatat tttttttctc aaggatactt tgcaaatctg tttcaaagaa actatctggt
     3361 gtgtgtttaa ttataatttc ttcattatct agtggaaaaa caattttatt tatttctgaa
     3421 ccatgagtat taggaagaaa aaaagaagct gttttatctg ttgatatatg ctgtatatga
     3481 ataactggta aattgttttt tctaaaaaac agtagtattt ttttagcatt ttcagcagtt
     3541 tcttctgatt gaaataattc acattttcca tttttaaaat aatcattttg aatatcaatc
     3601 aatattaaag ctatagacat gattatacct tctatttact tttattataa tactattgta
     3661 aaaaatgtaa attacttact ttttggtatg tataggatta cttattgtag caaattcctt
     3721 tattatctag aatttcttgt tgaccatgtt caagcatata ttcgattcct atttcttgca
     3781 ttatttccac tgcttttaac atttttttac cacgattagt aagaaaatat tcaacatgta
     3841 atggatatcc agcagaactt attttatcaa taatcccaaa atcacgtaac tcttttaatt
     3901 gttgaatcaa cattttttga tttattccat aaatattatg ttgcaattca gaaaatgttt
     3961 tattagattg tcttaattca aatataagga tagttttcca ttttcctttg attatgtcat
     4021 gtacaatttc aagaggacat gtatattcag ctcttatttt catagcatat cacccccagt
     4081 aaaatgataa taaattatat cacttgtctt gtgatatgac aaatatatat gaactgtata
     4141 taaattttat gttttattaa gttctaaatt tcttctattg tagttcatat ttagtacata
     4201 aataattagt aagatataag taaataaata tataacatga ctatagaaat ttaactttaa
     4261 aataacttat gataatttag aggaggaata tatatgaata tatcaagaaa agctatgaaa
     4321 ataatagaat tagcacaaaa aattgcaaat aagagaggta tttcagtaga agaagcttgg
     4381 agtgaagcag taacagaata taaaaataaa tacgaacata ttgcatagat atttaaaaat
     4441 ttagaatatt tggtagaata taatgatttt aaatgatact ataaattata aggtatatca
     4501 ttattaacat agaaggagga tatctgcttg attgtaaaaa tagataatac tttagaaaaa
     4561 gaattttggc aatatgtatc acatgaagaa agtttaaatt tattcataat tggatacgtt
     4621 gagaattatg gatttagctc tcaatatcaa gatatatggt ctcaggtaga agatggaaat
     4681 ataacctcta taatattaaa aaataagtca acacttataa tttatagttt taaaaataat
     4741 tttgatatag gagaaatgaa gaatcatata aaagatttag atgtagaaag cataagtgga
     4801 aaaaaatgtg taatagatag actaataagt aaatacaaag atttttatga aaaactagat
     4861 aataaatttt gtgtattaaa agaaataaaa gaaatagatt tttccaacat gaaggagtat
     4921 aaaatagaaa atgctcagga aaaagatatt gatgaaatag gaaaactttt aaataggtca
     4981 gactataaag taagtaaaaa ttacatagaa gaaaggaaag aacatttaaa agagggaaat
     5041 gtaagagcat attttattag aaatgatgat actatgatta gcactgtgtc aactggtatg
     5101 gaaactagtt ttttggcaat ggtggtctct gtaagtacag ataaaagata taggggaaaa
     5161 ggacttgcaa gttatatggt ttacaatttg agtaaagaat tattgttgga aggaaaagtt
     5221 ccatgtcttt tttataataa tgatgtagca ggtaaaatat atcataatat aggatacaaa
     5281 gagataaatg aatggacaat tctttttaaa tagctataaa aataataaat tttcgtgtaa
     5341 ttcttaacgt gtattgtata atcgctcaaa tacttgaaag gtgtctagta gatgggtttg
     5401 ttagcattta tggtctcctt atctaagtaa agttcccttt ggaaatcggt gaaatactct
     5461 tttacatttc atgagtccta taaaatctat gacataagaa agacccagtt acattgagta
     5521 attgggtctt attatcatat atattgtgtg cttacatgat atagttcatt tctataaacg
     5581 tagtatttcg taagtgggaa ccaatttttt aacaagtgat tatttgaaca aagcaataag
     5641 gatatgctag cagatggatt ttgtataatt taaaaatcaa tatttagact ctatcatgta
     5701 ttttcatcat cataatccaa tttgaaattg tatctaaaac cagtttgcta tttccacagt
     5761 tacagtggtt actagcttgt tctgcttctg tcataagcct aaatgtaagg gatcggacat
     5821 tgttgagtaa atcaatctct ttaccaacag ttctataatc aataaaatga tcttgtgttg
     5881 cacctaaaat caaaatgtct tggtttatat tttttgcaat agaatctatt tgataatact
     5941 tgattttctg aaaatattca tagggtgtag acgcttcata tgcgtacatt ccatgtttta
     6001 aaccccatac caccatacta tcgccacttt tcattttttg ctttattata aaattgacta
     6061 gccattttgt tttgagtttt agcagtagtc taagtagatt ttgcattttt attggttgtg
     6121 aaccaactat tatgtctaag aaattgggga atacagacca agctaccacg cgttcaattc
     6181 gtttttcgaa ggctgctgct cgtggagcaa gaaaacctcc caaggaagca cctacaatag
     6241 ttatattctc taaatgaaaa taatctaaaa ttgtcttaac gggacgttcc cattgataag
     6301 taaagtgttt tccctgcaaa cgcatcactc caccttgacc aggtccctca aaaagataaa
     6361 tatcaaatcc ctgtgacgca agataaagca ttgggaaaaa gaattcttca aagtaagaat
     6421 catttccacc gtggagcaat ataacatctt ttacctcgcc ttgcgctttt gcatacatta
     6481 caggtagggt gatattttca tatggtacat gaaaaatttg tacagttcca tttgagaaat
     6541 attcagagta gtagttgtag aatagagtag ttgctttttt gtagactgat attttatcag
     6601 ggtcaccatc atacataaaa aattcactca tacgatagta agcaattgca ttttctgtgc
     6661 gtccatcttg ttcagcttct tgtgccagat acataagttc tgttttccaa ctttcgctat
     6721 cgacaatttt agaggaaact ttttgtatat cttccaagcg ccccccatcc cacataataa
     6781 tcctgtttaa ctgaaaatta aaattggcat ttgtattaag gtaatataga cctttattaa
     6841 aagaaatttt atttgttttc aatgtcatca ctcctaaaaa gataatgcat agcaataaag
     6901 agtaatcttt aatgctatgc atttattgta acaaatatta gaagtactga ctttcaaata
     6961 gacgctattg gcggataaaa tatattttac attttcctat aagctcactt gcagtaatgc
     7021 caagatattt tttgctggaa gctgagaaat gagacggtga actaaaccct gcgtccatag
     7081 cagctgaggt aatatctcca ctttttaaca ataactcata agccttgcga agttttgata
     7141 aagccaaata gctgtttagt gatactccca tttgttcttt gaaaagatga gaaaaccggc
     7201 ttttggacaa ttttacttcg gcacatatct caaaaaagat ttcattgtga atgtgtgtgg
     7261 actttagaat atgattcaat gcccattgta ttctactgtc tgtaatagac gaaatatgat
     7321 aatttaaatt caatagacgg aaagcttgtt ttgaaaaatc aatatagctt tgggacaatc
     7381 cttttacctg acaagctgta taaatatttt gtattcgttc aactataaga ttatctataa
     7441 cgaaaaaaga gtgatttagt aattggtgtt gactaatatt ttgggcgagt atgcttgtat
     7501 catctatcaa gaaaaccaac attttattat ctttacttga caccgtatgc gatacattgg
     7561 aatcaataat aattccttta cattgtaatg attcgccctt atcaaacgtc acagataagt
     7621 taccagactg tgatataata atatgttttg caagatgttt atggatagtt ggttgtctat
     7681 actctgtatc taaaaatata tggtcaatca ttacacaaat ggtagtcata gctgtcaact
     7741 ccttgttcat agcttagcat attatacagt ttttaacaag aaagcttagt gattacaagt
     7801 atttaaaaat cctattttag gcaatgaaaa ataaaaaact ctatcgagaa ttaaagtatt
     7861 tataaataac tatattttta ctatgattca tgatagagtt ttttaaaatt tatgatacta
     7921 ttttttatta tttaaataat caagtgtttt aagtttataa ccttcttttt cccaatgtgt
     7981 aagaacctca tctaatatct cagtatttgt tgatgaattt ggatgcagta aaactattgc
     8041 accaggatga gttcttgaat aaattttgtt tttggcaaat tcatgagtag gttgtttctt
     8101 ttcataccaa tctacataag caaaactcca aaatattgat ttatatccta aatcttgtgt
     8161 atattttaaa gattgttcgc taaatttacc cattggaggt ctaaaatact taggcatttc
     8221 ttttccagta acatctttgt atgctttttc tacacttgta atttcttctt tgaatttttc
     8281 aaaatctgta atacctgcca ttgatggatg gctttttgaa tgattacaaa ctaaatgtcc
     8341 ttctttttcc atacgcttta ttaactctgg attgcttttt atataacttt caactacgaa
     8401 aaattgagct ttagcattgt gttttttaag cgtatctaat aattttggag tgtttccact
     8461 ttcatatcca gcatcaaatg atagatatat aactttttca ttgggatttc ctacataata
     8521 agctccgtat tttttaaaaa aatcagcttc ttttataggt gatggctgtt taccatcctc
     8581 cctagggtta aaataccaat catattcatg tgtgtcgagt gttggactag aaatttgagt
     8641 ttttgtttta tctaatgatt taaaatttat actagcaatt ccaaaaagta ttagagcaaa
     8701 tgctcctatc ataatgtatt tttttaggct atcttttttc acaatttcac ctcttattta
     8761 aaatttaaag tatatttctt ataatatagt ttgaatattt atagttaaaa atattcacat
     8821 atacaaataa taaatgaaag aagtttactg taagatataa agttgatatt aattatctta
     8881 aataaagtgt atataaatga taaaatataa agagaaatga ttgtaaataa gttaggctgg
     8941 tttaacttga agggatataa aaatggataa tataataagt gtattgaatg atgttgtttt
     9001 tttagatata gaagttagtg gattagattg tttaaattca gaaattttag aagttggagc
     9061 tgtcaaggtt aaagactgga aaatatatac ctatgaatca ttaataaaaa acaaatttga
     9121 ggtacctata gaagtattct cagtatgtaa aaatttagat aaaaatgatt tagaaatagc
     9181 taatgaaata gaactggtgg aagatagact tgtaaatttt gtagaagata gtttcattat
     9241 atgtcatgat ttaagtctga aaaaaaagtt ttttgagtat catatgccaa agttaaaaaa
     9301 caaatttatt gatttaattg aattagcagt tattttagaa ccatatcata aagattatag
     9361 cttagaatac ttaaaaaata ctttaacaaa ttgtaattct aaagtggaaa atagagcttt
     9421 atcagatgct attgatataa taaatattgt aaattgcctt ttagtaaaat ttaataacta
     9481 tgaaaaaact actttggagc cattgagttt taaaataaat tcatatctta aaaaatttaa
     9541 tcttccaaca tgggaatgga gcaaattttt agaagaggca aattatgatt tatcaaataa
     9601 tataaatata aaaaaagaat ataatatatt tgactcaaaa gaagaaaaga agaaggaaag
     9661 agaaacctta aaaattttaa atgaagaaga aaaaaattat gaagaattat taaaatacaa
     9721 aactatttgg gagaataaag aaggatttac atatgaatat agacctggtc aatatgagct
     9781 tactaaaaca ataagagagt tgtttagaaa tagcgaagat gaagaaaaaa ttgcatgtat
     9841 agaggcacca actggtatag gtaaaagtgt aggatattta ttgcctgcaa tattagaggc
     9901 tagaattaat aaaaaaagat tattaatttc tactgacaca aaggaattgc agatacaatt
     9961 aataaataaa gatattccaa atgtgttaga ttctttgggt ctaaatggaa aagtaagtta
    10021 cggatatata aagggaaaaa ataactatat ttgtatagat agactggaag catatataga
    10081 tgattatgag tctcaaaacc ctactaaagg agaaatttta tctttaatat ttttgaagag
    10141 attagttgaa ggtggcaagt atggagatat agaagaaata aattatttag tgtttgacaa
    10201 cttcaaggaa ataagtaccc acttaagaaa tgtaagttgt gacccaaata tgtgcagacc
    10261 taaaaaatgc aaaaaagatt gtttatataa aaacagaata gaagaattaa aagaagaaca
    10321 tataacagta gtaaatcatt cactattagc taaatggccg tataaggatg aaaaaccttt
    10381 agaaaatata atagtagatg aagcacataa tttgactgaa aaaggatatg atttcttttc
    10441 aagcattata aattcaaagt ctttaaggta tttattacaa gaaatttatc cttacgagtt
    10501 tattcaaaat agtagcttta tatataaaaa atatagtaga aatatgagaa aaataaaggc
    10561 ttttgataaa ttttataatg tattaaaaat tggaagagaa gataaacaaa aaattgctag
    10621 aagtataaat ctcattattg aagagataga ttcaatatta aagtttggta attgtaatga
    10681 atataataat gtaagtaatt ataatttaag atgggaactg aatttgcaaa tagatgaaat
    10741 tgtgggaaaa ctaaaaaagg atggtataga tactgaaata agttatagag cctatagtga
    10801 aaagataaag ttgagttgtg agaaaataat aaaaaattta gtttcaataa taataataat
    10861 ttataggaat attgatgatg atagtataga taaagaagca gatatatata aatttggaaa
    10921 ggcaaagaca agagatttag aggatataaa gattatattt gaaatctttt tagagtatga
    10981 tgaaaaggat gattatgcaa ggatagttga aattgataag aattataatg actttgaatt
    11041 tcgagtagta ccattaaaaa tagcagattt atttgaagaa aatattttat ctcaattaga
    11101 aaaaggaata tttttatcag caactttgag tttatctgaa agtatgtctt attttaaaaa
    11161 tacattagga atagacagag ttaagaatgt ggaaaagatt atagaaccaa tttttgatta
    11221 taaaaataga gtctctgtag ttggattttc tgatatttgt gagtacagaa attctgaatt
    11281 tccaaatgag atgagtaaaa ttatatctaa tatatcaaag attacagaag gtcatacatt
    11341 agctcttttt aatagtaaag atagacaaga aaaaacttat gaaatattga aaaaatactt
    11401 acatagtttt aacttagaaa tttatgctga taaaaagggg attagacacc ttaacgattt
    11461 aaatagaaaa tgtgtagtac ttggctcaaa aggatgtttt gaaggcgtag acattccagg
    11521 ggatggtttg gtttgtgtaa ctttagacaa gcttccgaat ctaaatccaa aagacccttt
    11581 gtattttact ataatgaaga agtatggtat agactactat actataaatt atcctcaaat
    11641 gaccataaag gtaaagcaag ctatggggag aattttaaga agcaaatatg actatggatg
    11701 ttttgtgatt tttgatgtag gaactaatat aagtgtttta aagagattag agaaagattt
    11761 acacgattgt aaaatttcaa aggttaatag caatgagttt tatacttata taaggcgaca
    11821 tttaaataaa tctagaagtt taatactaaa atctgttata tttgatacta taaaagcgtt
    11881 gaatgttgat gctaaaatgg ataacaatga tgttgataaa gatattataa aaaaagatat
    11941 aaatgaaaat ataagacaaa gagctgtaaa aggagaagtg taccatattg atattataaa
    12001 aaaagatatg aaagtaaaat attttgatag aaactatctt ataaatttag atatatttat
    12061 gagagaagaa gataaaaatt aagagtggga gtgagatatt tggcaaaaca aaagttttat
    12121 gctgtgaaaa aaggtaaaaa tataggtgta tataatacat gggatgagtg caaaaaacaa
    12181 gtaaatggat tctcaggagc tgaatataag agtttttcta cttttcaaga agctaaagaa
    12241 tatattgatg ggtcagaaaa attgagtttt caagaagata aggagtttat agaagcatat
    12301 gtagatggaa gttatgaaca ttcagtaaaa atgtatggtt cgggtgttgt gattttaaaa
    12361 aataatgaag ttataaaaac ttatagtgaa aaaggaaaag agaaaacttt agtaagtatg
    12421 agaaatgtag ctggagagat agaggcttct aaaattgcaa tgcagtactg tattgacaat
    12481 aatgttcaaa acttgatttt atactttgac tatgaaggga ttgaaaagtg gtgtactgga
    12541 gtttggaaaa caaataaaga aggaactata gcatataaaa atttctatga cagtattaag
    12601 aataagctta atgtaaaatt tacaaaggtt aaagctcatt ctggaaataa gtataatgag
    12661 gaagctgata aattagctaa aaaagctatt ggtgtataat aaaaaaatat ttatacataa
    12721 ttacatggta taagagtata tctaaattcc tactttataa ttaaacaact tgtaattaaa
    12781 caacttgtaa ttaaacaact tataattaaa taaattttga ttaaaaaagc agattgtatt
    12841 atgaaaaaat aagtatctaa tttataaaca attaataata gtattaatta gatacaactt
    12901 atttaatata ataaaatctg ctttttatat aactataaaa tcttcctaca ttctattaga
    12961 attgcccata aataccttca agttcttctt ttaatacttc agggtcattt ataccaatag
    13021 acatggttct agccagtata tttgcttggt cataagttga tgtccatgag aatacaccac
    13081 ctagacaatt tctaagaaca tattgagttt ttaagaatat tgataaagca tcatcatatg
    13141 acattgcaaa atctccatcc ttaactaaat acggaacttg agcagtatta tcaaatctat
    13201 attcatatcc atttttattt atataatccc ttctaagctc atcataagtt cttgttatag
    13261 tggcacctaa tcttccataa aatggtatac cgagaaggat tttttcagaa ggcattccag
    13321 cattctcaag atttctcacc attgcatcaa cactatatcc tggcaaagat aagtctgaat
    13381 caaaaagatt tgcttgatgt tttctaccat ttgggcctgt ttcacctgct gtaaaatcat
    13441 aactcataag attaaaataa tctattatag gagctatttt atctatttca gcacttgaat
    13501 ttatatatcc tctatctcct gttccagcta cactaagcca tttatcatct cctataacat
    13561 ctcttatggc agttagtaag agtgtaaagt tttctctatc ttgaggtctt gatgttattc
    13621 cagatgcact acttccagga tattcccagt ctatatctat tccatctaaa gcatattcat
    13681 ttatcatctg attgacctgt cttgcaaaat tatatctaga tgtaggtgtt aatgctgcat
    13741 cagagaatcc ttcagctccc caacctccaa tagctacaat tacttttaag ctaggttttt
    13801 cacctttaag agcaagtaat tgatttaaaa atctaggata aggaataaac aaatttccag
    13861 actggtctat ctcagcaaaa gcaaatataa ctgcatctaa tagttgagca tctacattag
    13921 ttggatttcc aagaacatat tctgctacaa ttggatttat atctggacag tttgcatttt
    13981 caactattgg attgtatggg tctgttattt gtggtctaac taattttttt gaatctttta
    14041 aagttttcat agctattttt ttagtatttt tttcgctagt ataatcgtag tttttataat
    14101 tatgtttata gaaatcttca taactactat cttctttgtt atagctagaa tttattttgt
    14161 cgcaagattc atctttatca tagttaaaat tcatttcatc acaagactta tctttaaact
    14221 tatcttgttt ggagttgtga actttgttag tatttttagt atgttttttc tcatggttgc
    14281 aatcatcttt aatatcagtc ttgtgttctt gtttacagtc aagagctttg ttcaggtagt
    14341 catgatgttc atgttcacag ttacattcat tttcaatgtt tttagtatgt tcttttttcc
    14401 agctacaagt attatcaatt ttcttgctca cttcttcatc attataatta tctggtacaa
    14461 aacataagta ccagtccata catgaatatt tcttattaca actgttaact ctatttttta
    14521 attccttata gtttttagga taaggtaaaa tcactggcat tccaggaaac cagtttgcag
    14581 gagtaactat attatctcta tcactagtct gaagtgcatc tactattcta agtatttctg
    14641 gaatatttct tcctgtagtt agtggataat aaagaatcgt tcttagaatt tgattattat
    14701 ctataataaa tacagagcga acagttgatg tatcactcat tggttttgat atcatgccgt
    14761 ataacttggc aattctcata tctctatctt ctataatagg aaatggaatt tctacacctg
    14821 taagtaaaga aatattatac atccaagcta aatgtgaact gttactatca acacttagac
    14881 caattagttc tgtatttctt tttttaaatt cgtcataata tttagcaaaa cataaaaatt
    14941 ctgtagtaca aactggtgta aaatcaccag gatgtgaaaa taaaacaatc caattaccct
    15001 tatagtcaga gagtctaata ggaccatttg ttgtattggc tttaaaatca ggagcctttg
    15061 accctaaact tggcaaattt ggcatgtaaa tcacccctca ataaattatc atttatttta
    15121 ttctattaat taatacatat tagtgttact attttattaa aagttaagta atccttatgt
    15181 caaaaaaaga tatttattaa aaagatttaa tattttccta atataaatga caatagtaat
    15241 tgctattttt ttactaattt ggtatagtaa tggataaggg gtagtgtcaa ttttagtgat
    15301 tatacgaggt gattggattg aaaaaaattc taagaatttt agttatctcc atgatgatat
    15361 gttttgcaat gacttttgca ttagtgttaa taaattcagt tatgggagta catataggat
    15421 tggattatta ctttttgatg ggaagtgtgc ttacagtttg tttaacaatt ggaattgttt
    15481 tatgcaatgc tagaaaaata tttgatagca aagctataca caagacaaga acgaaaactg
    15541 tcagtactaa taaaaaacaa aagagtcatt ctagggatat aaaaagaaag atatcataat
    15601 ttatgtaaag gaaatattta tgtataaaat aatgattgat aggtaaaata aaaacacgat
    15661 ttaacttgtg tttttatttt ttttcaagaa ttatgatata ataaccaata agaaatttag
    15721 tttaccataa aatataaaga ttattaaatg gagagggaac tataatgaat tttagagatt
    15781 tatttgagaa ggctgtagat tttattgatg aaaaaaggaa atctatagtt gcgatttcat
    15841 tatcaacatt aggtgtaatt gctttgataa tagtattttt cttaagtagt aacgagttta
    15901 gtgtaggaaa tgaagctaat gagttgttaa agattataga gaaaagacag tattctatag
    15961 ctgttgatta ctacacaagt atagaaaaaa agttttctga ttcaaaaatg gaaaggttta
    16021 ataagtctgt ttctaaaaaa ataaataaat tgctattaaa tagtggtgat aaatatttag
    16081 atggagacat aagtcaagaa agttttattg gattaataaa tactgtgaaa gaattaaaca
    16141 aaataagtat agatgtggat gacttattag ctcaagctga tagagttaga gaaatgtata
    16201 aagaagaaaa tactacttat gatattgcca ttaactacat aagtactgtt tcaatattaa
    16261 atggtatggg tagtaaccta gatgtataca aacagaatat agaaacaatc aaagagtcta
    16321 gagatgttta tgactcagca gtaaaagacc aaaaagcata taagtattat gaagctattg
    16381 aaaagtataa taaagtatta aaagaagatg aaaagtatta cagtatggct caaaatggga
    16441 aagaacaatg tattgaagaa atgtatgatt actatataag tagagctgaa gaggcaaata
    16501 cttctggaga ttatgaaaga gcattacaat atattgagta tttaaaagaa gattattcag
    16561 atgatgaaaa ggtacagagt ttagaaaaaa aatataaaaa gaatttatca ttgtatacct
    16621 taacatctga tgacattata aatgtaatag ctaaaaaaag tggcaaagac aaggcaaatc
    16681 tatctataaa ttcacttcca caaatgataa aaaataataa atactattat gctgaagtat
    16741 atgagtatga taaattaata aatgaagttt tggtaagtgc aaaaactaaa gatttatatt
    16801 cgtataaaga tggtaaaaaa gattacaaag tagattatgg tgatggatac tttagaatat
    16861 tagaagatgg aagttatcaa tttggtatta caaaagataa agctaagttt gtgttaacta
    16921 atactcttga tgaaaaagaa aataagtata aaaagattga gatattagat atagagaaag
    16981 cagatagata tgtaaaaagt aaaaagagtt tagaagaatt gtttggaaaa tataaaaata
    17041 tttattatta tgctgtagta aataaaggct tatttagagg caaagaagtt tatgctatta
    17101 atatttacaa tgaaaaaata tatgccatat cagaaaatgg actaaatgaa tattaattaa
    17161 taatattaaa ttaatatata attaaaaagt ttttggggtt ttaaggcgca ttatgtagta
    17221 atataataat agggatatat aaataatttt attgtaagga gaagtatggg atgagtaatg
    17281 tgaacaaaaa gctagttata gctattggag ctgtagcatt agtagcaata atttttatag
    17341 gcataatgtg catgcaattt aaaggggaga aaatagcaaa aaacacatat gttaatggag
    17401 tagatattgg aaaattaact aaatcgcaag caaaacagga attagctaaa aaatacaaat
    17461 tagagaatgt tgagtttaat tacaatgata aaagttggaa agtaaagagc aaagatttaa
    17521 atttatctac tgatctggat aaaacagtag aaaacgcata taatttaaat agaaagagta
    17581 gtttctttgg caatctatca aaaactattt caacaaattt tggcaaaaaa agcaacttag
    17641 tagttgtgat aaattatgat aaaaataaat taaaagcaga aatggaaaaa atagctaaag
    17701 aaatagatgt agatgtaaaa gatgctacac ttgatataag tggtgaaaaa gtcaaggtta
    17761 taccagattc tgatggtctt aaaatggata tttctaagag tatggagaat tttgataatc
    17821 aaactaaaaa aggtaactat aaaaatgagt tagtagtaaa agctactcca gcaaaagtaa
    17881 aaaaagagca acttactaat atagatacaa atttaggtac gtattcaaca atatttaaaa
    17941 cttctcaaat aaatagaagt ataaacataa aattagcaac agataatata agtaatgtat
    18001 tacttatgcc aggagaaact ttctcattta ataaacatac agggaaaaga agtaaggaaa
    18061 atggatataa aagtgcacct gtaataatgg aaggtgagat ggaagaagat tatggtggag
    18121 gagtttgtca agtttcatct acgttataca attctgtgtt atacgcaggt ttagaaattg
    18181 ttaatgtaaa aaatcatact ataccatcaa gttatgttcc aaaaggaaga gatgcaactg
    18241 ttgcagatag tggaatagat ttcttattta aaaataatct aaagcatcca gtttacataa
    18301 aaaattacgt ttcaggaaat caaattgttt gcaatatata tggaagtgca gaagataaac
    18361 aaaatataac gatatcaaca aaattagatg gcgtttcaca aactacaatg aaaagagtta
    18421 atgaccctac aatgcctaaa ggtaaagaaa aagtagacaa aagtggaaga aatgcatatt
    18481 ctgtatcaac atatagaaca tttaatgatg caaatggtaa aaaaattaaa actgaaaaaa
    18541 tagctaattc atattatcct aagaaggaag gtattatatt agttgggact atggaaccaa
    18601 aaccagagga aaaaccaaat acagacgaaa ataagaataa tcaaaataca aacaatcaaa
    18661 atccaaataa tcaacaaaaa ccagaaacac caccaactga taataagcct aatgagacac
    18721 aaccacaacc gcaagcttaa agttctcaag aataggattt atgtagagta ataaaaaata
    18781 taaatctaaa taggagggat tactttgaat ttaaataata taacgaatta cgttcaaagt
    18841 atttgcgaga atatttctaa tgtattggat gtagatgtta ctttagttac aaaagattta
    18901 actaggatag caggtacagg aatattcaga ggtaaaatag gagagacaat atcagagaag
    18961 tcagtgtact ctcttgtttt aaaagatgga aaatcctatg ttataaataa ggaaatagaa
    19021 gagaactgta ataaatgtgc aaatagagaa aattgtaaag aattagctga tatatgtact
    19081 cctgttaaaa tgggagaaca tatacttgga atcttgggta tagctgcgtt taatgaagag
    19141 caaaaagaaa agatactttc aaaagataag gagttaactg cttttgtaag gagtatgtct
    19201 gatttaatat cttttaaact agatgaactt tataaacaag aagttaagac tatagatgac
    19261 cttgagaggg aagctataga aaatgccata aagaaatatg gaagtaatac agaaggtatg
    19321 aaaaaagtag ctgaggcatt aaatataggt atagctacac tctatagaaa agtaaaaaaa
    19381 ttcaacatta aaagttaata gtattgaaaa agaggtaacc tttttatgaa aagaagagga
    19441 ttaccttttt tattatgaga atggtggaaa aatatgtata gttttgactt gacatattaa
    19501 atatgttatc ttaaatatat attttagagt ggaggtgagt attattttag ttaaagatat
    19561 aaaacaagac atagaaagca tgcctagaaa aattttagat atatctttga tagaagataa
    19621 taaaagtgat ttgacttttt ttaatataga agaagaagac ggtgatgaaa cattaaaagc
    19681 attaaaacag agttatgtga ctacaaatta taaagaagaa actctattaa acttgcaagg
    19741 agctttaaat tcaaagtcag acacaacgtc taaggagtta aaattagaat catataaaag
    19801 atataacaat gcattggatt tagcatataa aaattatata actagtgcca ttaatatggt
    19861 taataaagct ctggagataa atcctaaaga tattgatata ctaaatctta gaggtctttt
    19921 aaagttatta aaatgtgatt ttgctaaatc atttgagagt ttttatactg ctttatgtta
    19981 tgagaataat catatatcta gaaaatatgt aaatctaatt tcatctgaag attttaaaac
    20041 ttttttagga agatacaatc attctataag atttataaat gaagaattaa attatgagtc
    20101 aatacatatt ttagagaaca taattgaaga agagcctgag ctaatagagc catatgtaat
    20161 cttatctttg ttatatgata aactaggtaa tgtaaaaaag agagaaggat atttagacaa
    20221 acttaaagag ctagataaag ataatcctgt atttgaaaaa aatgaagaag aaaaagaaga
    20281 tacaagtaaa aaggaagaaa taagaaaagt aaaaagaaag aaaagtattt taccatatat
    20341 tatagttggc tgtgttttaa taggtatggg gatatatttg attcaaagca aaaagagaat
    20401 agaaaacttg aataaccaaa taagtagtaa agaggaaaag ttaagtgaaa ctgataaaaa
    20461 gttaggagaa acgagtaaaa aattagaaaa aacgaataag gaattaaatg aggttaaaaa
    20521 taaagaacca gaaagagaga taactgtagc tgatgaggaa gatttatatt atcaagctct
    20581 aaatttaaag aaaaacaaag aatatgaaaa agccatagat aattttaaaa gtgtagtttc
    20641 ttctggtaaa actaaaaaat atatttctga gtcaatatat caattagcaa taacaaataa
    20701 attattagga aataaggatg aagctataaa atattacaaa aaatatataa atacttatac
    20761 taaaaatgac cagtattatg atgattcata ttacgagttg ggtatgcttt attatgataa
    20821 tggcgattta aaaaatgcac aacagacttt ttatagtttg agaagtgaag ttccagacag
    20881 tatgtataac aattcaaaaa taaaagaaat cttaagtgaa aaataggttt atatagttaa
    20941 gttttttgaa acaaccaagt atgtatttta ttaaattaaa ataaaaataa atttaaaaag
    21001 agattgtgtc aaattataac tttctatttt aaagaaagat atttgcttgt tgataaaact
    21061 acaaatatat gatttgaagc aatctcttta atttttggag gtggaaaatg aaagttttca
    21121 atcaattagt aataatttta tctatctggg taataggaga gtatataagt tcctttatac
    21181 aaggaattat acttattcct gggagtatag ttggtatgct attattattt ctactactac
    21241 aatttaaagt tttagacttg agtagtatag aaaatgtaag tggatttttc ctcgataata
    21301 tggctatatt ttttattcca gcaggtgtat cacttataaa gtcattagac ctaataaggg
    21361 aaaatgtatt agtgctttta ttagtcatat gtttaagtac actaatagta atgtatacta
    21421 ctggaattat tgtggagaaa atgataaaaa agaaggaaga aggacaaaaa aatgtataat
    21481 gtattacaga caccagtatt tggtataata gtaacaatag tttttttcaa tttaggaaga
    21541 tacattcaac gaaaaacaag taatcctata tgtaaccctt tattaattgc aatcgtagga
    21601 ataatattgt ttttaagcat atctaaaatc ccttatgaga attacaagat aggagctgat
    21661 agtctaaatt tctttttagg tcctgtcaca gtagtacttg cagttccact ttataaacaa
    21721 tttgaattat ttaaaaagca tatgtttgag attattgtag gaataggttg tggtatagtg
    21781 atttcttttg tatctgtatt gataattggc aaaatagcta attcagatgt aagtataata
    21841 aattcactaa ttccaaaatc tataacaaca ccaatgggaa tatctttagc aaattcttta
    21901 aatggtatag aatcaataac agttgtagcc ataattttta caggtatttt tggtggtatg
    21961 gttgcttcta cagtattcaa actggggaat ataaatcatc cagttgctaa aggaattgct
    22021 cttggaacat ctgcacatgc tttaggaact acaaaagctt ttgaacttgg agaaatagaa
    22081 ggagctatga gtggtgtttc tattggagtt tctggtacaa ttacagtaat actaattcca
    22141 attataatga attttatata aaaaataaaa ttaagacgag taccttgaat acttaaaaca
    22201 aaataaaata aaaaaaattt aaaataaaaa ctgaacgaaa aaaatgcaaa taatgaaata
    22261 aaaaaatcat gtactgaaat tataaaaaga aaaatttcat ttaggaatta attataaaga
    22321 gataattact aaacttgaat ttgctaaaat aaaataaatt actgcgaaaa tagatattta
    22381 gaaaaaaata ctataaattt actatattgc aagttaaata ataagcagta tcatattatg
    22441 ctagaaaaag tttcatttaa ggcataaatg agatgatttg aacgttttta aagattagaa
    22501 tataaaagat tgcactagac atatatgaaa aagataatat aatagatgat gtaatagatg
    22561 acagttcaag aaattataaa aaaaatttat ttgaaatatt atctattaca tcaggaataa
    22621 tatatgtaag agtaagcttt taaaattcta aagatttaga aagattgaag ggagaaagaa
    22681 atgagtgaag ttaagaatac cctacaaaaa catccagttt taagatattc aacaatgcta
    22741 tttgggatgt tgatgacatc tataggaata aatgggttct taagaccagc acatctgctt
    22801 agtggaggtg ctacaggtat agcaacatct ataaactatt tgacaaatat aaatgtaggt
    22861 ttattaacat ttttaatcaa tattccaata tttatcttag ggttcatata ccttgaaaaa
    22921 gagttttgta tttcaagttt ggtaaatatg attgtatttt cattattatt aggagcaact
    22981 caggaaataa gtaatattat acctatacat gatatattgc ttcaaagtgt atatggtggt
    23041 atattatctg gtttaggagt cggagttgta tttagaacta ggtcttctca aggtggtaca
    23101 gatataatag ctgcaatact aaaaattaag aagaatatag aaatgaaaga cactgcttta
    23161 gcaataaatg gcttgatagt acttacagga agttttttat ttgggttgga tttagcatta
    23221 tacactctta taggtctatt tctaaatgcg tattcaatga gttttattaa agatgcaatg
    23281 aattaccaaa aatctgttat ggtaatgtca aatgaagtcg atttaatagc agaagatata
    23341 atgaagagtt tagttagagg tgtaactttt ttagatgcag aaggtgcata cactcatcaa
    23401 aaaaagaaga ttatatatac aatagtttca tcaaatgaga taccaaagat aaaagatata
    23461 gctttgaagt atgataaaaa ggcctttata tctgtaaatg atgttacaga agtaaaagga
    23521 agagggttta aagcaaaaga tttatagaaa attttacaag ctgggagttt ataatgtaaa
    23581 tttgtatatt atatctctca gcttatttaa atttagtata tgaaaataaa ggttttatca
    23641 atgatttgtg tatcacttta aaagatatca ttttaaaatt aaaattgaaa aaattactca
    23701 atatgtagaa aacataacca ctattaggat ataataaatt taatagattt agtaaaatat
    23761 ctaggaataa cgttggagga atagcattat gaatttatct aaagaatatg ttaatttgta
    23821 tgataattat ttgaaatata taaatgaagt aaacaaagag attagaagta taaagaacat
    23881 gaagaaacgt gttttaaaaa agggcgattt tgctccagaa aatgaagtat tagaattgga
    23941 aggaaaaaca atacgcgata tagatgatgt cgatacaaaa aaaccaaaaa ataaaatata
    24001 taaattttca aatggggatg tgtatgtagg aaaattttta gaaggaaaga tggaagggca
    24061 aggatcatat actttttttg ttgatgaagg aacggctatg gagtacatag gagagtttaa
    24121 agaagacaaa aaaaacggaa aaggaaactt tgtattttca aatggaaatg aatatatagg
    24181 ccattttgag gaagatatga tgaacggtat tggaaatatg ttatataata gcaaagatga
    24241 atatattgga acttggaaaa atggaaaaaa agatggaaaa ggtatttata agtggagtga
    24301 tggatgtata tatgcaggtg aatttaaagg tggaaagatg gaagggtatg gtatttgcta
    24361 taatagtaaa ggggaagtac tttatgaagg agaatggaag aataatttga ttcatggtaa
    24421 aggaacttat atatgggaaa aaggtaaaaa gtatataggt gaatttatgc atggtaaaaa
    24481 acatggacaa ggaacttttt atctaaataa tgaattggtt tatgaaggga cttggaaatt
    24541 tgataagcca tccatcttcg acagaacatt agatgaaata ttttcattaa gactatagct
    24601 ttatctatta atagataaag cttttttcta atacttactg taaataagta tgaatgatat
    24661 tgattagtat acactatcaa tattaactca ataaatgtga tattaaaaat ttttgattga
    24721 ttttaagaag gagggatata ttgaagagat taattgcttt agtgttagta atacttattg
    24781 ttttatttta tagccctgaa ttgatagaag aaggatatga tttaaaagaa aaattttttc
    24841 aaagtgaaat atggaatgaa tttttagaca aaataaatat aaataataat tctaagaaag
    24901 ataaaaaaga acaaaatcaa aatttacaat caaataatac tgaaggggag aacttaggag
    24961 agtcagatat aaagaatttt gaaaaaataa gcttaggaga taatttaagc tatgttttat
    25021 caagtattgg taaacctggt agaattgata ttagtgaata tggttttgat tggtatgtat
    25081 ataatcaata tggaaaagaa tttgcaatgg tcggacttga aaatgatgaa gtagtagcac
    25141 tttatagtaa ttctattaat tcatgtgaaa atcaagatat aaaactaaat caagatagac
    25201 aaacagtgag aactaagatt acaccattaa aatataagag aaaaggaaat accagatata
    25261 taataaactc agaaaatcaa tatgatataa taagtaaaga aggtaagtat attacaattt
    25321 tctacgatat tcatgaagaa aatagagttt gctcatattt aataattgat aaaagtactg
    25381 aagatgagtt taaaaaatta tatccagatg atagagaaga acttaaaaaa tgttttgaac
    25441 ttgaagttat agaccttgta aatagtgtta gaaatcaaag aggattaaac tcattgagat
    25501 acagtgaaca ggcaactttg agttcaagaa aacatagtga agatatgaga gataataatt
    25561 tttttgacca tataaataag aagaatgaaa ctccatttga cagaatgaaa agagaaggta
    25621 tagtatatac ttcagctgga gaaaacatag cagcaggaca gattaatgca atatatgcgc
    25681 atgaagcttg gatgaactct gaaggacata gaaaaaatat tttggggaac tataataata
    25741 ttggagttgg agtaatattt ggaggaagct ataaaacata ttacactcaa aatttttata
    25801 aataactaaa atatttgaaa ggaagttaaa aaatgacatc atggaaaaaa aagacagtat
    25861 ataagtgctt aatagcagta gtcttgtttt gtggaatagt gttaatatct aattttagta
    25921 aagtttctgc tttgatgatg gatactaatg gaaatgtttt gattaaacat ggttcaaggg
    25981 aaaaaaagct aatagcaatt acctttgatg atggtcctca tcctaaagaa actagtcaag
    26041 ttttagatgt attaaagaaa tacaatgtaa aagctacttt ttttatagct ggaaaacatg
    26101 caaaatggta taaagaacca ttagtaagag caagtaaaga aggtcacgag ataggaaatc
    26161 atactttcaa tcatcctgat ataagtaatt taagttctag tcagatagaa gaggagattg
    26221 ttaagtgtga agacattttg aaagaagtaa ctggaaaaaa acctacatta tttagaccac
    26281 catttggaag ttatagagaa aaagacttaa tagaaattgc aaaaaagcat gactataaag
    26341 ttgttttatg gacaggtgta gatgtgaaag attggaaaaa tccaggagct aatagcattg
    26401 cagataaaat aattaataaa gtaaaaaatg gagatataat acttttgcat gattatgcaa
    26461 ctaatgatac agttgaagct ttagatatgt ttattccaaa aatgattgaa aaaggtttta
    26521 aatttgtaac agtttctgag ttgataaaat aatttttagg ggggagattt acagtatgat
    26581 tcttatgata gacaattatg attcttttgt atacaaccta gtccaatata tagaagaatt
    26641 aggggaagca gttgtagtaa aaagaaataa tgaaatcaaa ataagtgaca ttgaagaact
    26701 aaatccagag gtaattgtgt tatctccagg accgtgttct ccaaaagaag ctggtatttg
    26761 catagatatt gttgagcatt ttaaggggaa aaaacctata ctaggaattt gtttaggtca
    26821 ccaaactatt ggatatgttt ttggaggaga tattataaaa gcacaacagc ctgtgcatgg
    26881 aaaagtatat agtatcaacc atactaataa aggagttttt aggggactta aaaatccttt
    26941 aaatgtcact aggtatcatt cactaataat tgattccaat acagttccaa aagaattaga
    27001 aattacagca attactgata aaggggaaat aatggggatt aggcataaga aatatttaat
    27061 agaaggagta cagtttcatc cagaagctat tttgtcagag tatggtcatg aaatgcttga
    27121 aaattttata acagaagcta gagaaagggt acatatgtaa tatgataaga gagataaata
    27181 ctaaattaaa ttcttttgag atatttacta tttttagaaa tgaacatgac agttttatat
    27241 tagacagtgc tatggataaa gaaaaattgg gaagatattc ttttataagt agccaaccat
    27301 ttaaggtatt aaagtataag gatactgatg aaaatccttt agaagtttta aaagaagaac
    27361 tacataagta tagggttgta aatgatacta atcttccatt tgtaggaggt gctgtgggat
    27421 atttatctta tgatttaggt aattacatag aaaatttacc tagaactgct gtagatgata
    27481 ttgagatgcc tgatatgtat tttggatttt ataatcatgt aatagttata gaccatcttg
    27541 tgcaaaaaac ttatatagct actccaaaca tagatatcga attagaagaa aagataatag
    27601 atgatataga acaaagaata ttaaaagaag agaaaaaagg tatagatagc atatgttatg
    27661 aagaaaaaga agtaacacct ataagactta aatctaattt tacaaaggaa gaatttaaaa
    27721 atgcagttca aagtgttaga gagtacataa gacaaggaga tatatatcaa gctaatttaa
    27781 cacaaaggtt cagtggagaa acagaactta caagctttga attgtatagg gacttaagaa
    27841 gatttagccc agcaccattt ggggcattct taaactttga agatacacat atattatcaa
    27901 attctccaga aagatttata agatgtgtta ataagagaat agaaactaga ccaataaaag
    27961 gtactcgtcc aagagggaaa gataaagaag aagatttaag acttcaacaa gaacttagaa
    28021 atagtgaaaa agatagagct gaactactta tgatagtaga tttagaaaga aatgatattg
    28081 gcagaatatc taaaactgga agtgttaaag ttccagagct atttgtaatt gaaccatatg
    28141 caaatgtaaa tcacttagtt tccacagttg taggtgagtt aaaagatgat aaagatgcta
    28201 ctgatgtaat aaaagcaact tttccagggg ggtctataac aggagcacct aagattagag
    28261 caatggaaat tatagacgaa ttagagccaa cgcaaagaaa tgtatatact ggttcaatag
    28321 gttatatagg ttttaatggt gatatggatt ttaatatagc aattagaaca ataatcaaaa
    28381 atgacaaaaa agtctatttt caagttggag gaggaatgac ttgggattct gacccagatg
    28441 aagaatatca agaaacactt gataaagcta aatccataat gaaggctttg aggggatatt
    28501 atgaagaata atgtaggttt tgatagtagt ttaagtaaat ttggaattgg tttgtttgaa
    28561 actattagag ttaaaaatgg aatagcagta gatttagata tccatataga aagaatgcta
    28621 agttcaataa attgtttgga tttagatata aactataaaa aagatttctt gataaatgaa
    28681 attgttacat atataaaaaa agaaaatgtc attaataaag cacttagaat tactgttttt
    28741 gatgaaggtt ataatatatc tattagggat attccatata atcaagagac gtatgagaag
    28801 gggtttaaat tagctatatc gccaatagtt agggggaata gtttaattca tagacataag
    28861 actactaatt attttgaaaa catatatacc aaaaatatcg caaataagac tggttataat
    28921 gatggtatat ttttaaattc agaaggtgta atattagaat gttctatgag caatattttc
    28981 tttataaaag gagaaagagt gtacactcct agtgatagat taccgatatt aaatggaata
    29041 ataaaaaaaa ggattataga gatttgtgac gaattacata tagagttgat agaaaatgaa
    29101 attaatatat cagaaattag tagttttgat tttgtttttg tcacaaatag tcttatgggc
    29161 gctataaagg ttacagaaat tgacaaaata aaatttaata aagaaaatgt tgtttttgat
    29221 aaaatagtga agttattaga ataaattaaa atattaacaa tttgttggag acaaaagatg
    29281 ataggttgta tttatgaagt atacaatgaa gagatgacta aaataataga aaaccaaaac
    29341 actttggctg tatatttagt aggttctagt aaagacgtag attttactct ttatgatgta
    29401 gagataaacg atattgatgt gttcgttttt gtaaaagaag gggaaaaaca agagagaata
    29461 ctgtttaaaa aaaagggaat agaatttgat gtaaattact tttcaaaaga tggtgtaaaa
    29521 aaattattat caaataggga atatttcttt gtgaaagaaa tgaaagatgc taaagtactg
    29581 tttgataggg agaatatatc aaatattata aaagatataa gtagagatat ttacttagaa
    29641 ggacccagta aaatgtcatt agaggaaaag tcttttataa agcaagatat tggagcaaaa
    29701 atatcgaatt taaaaaataa agaaaaattt gatgtttttg aatatcattt tttgacgaat
    29761 ttatatttaa aagatataat aattgggtac tttaatataa atgataaatg ggtaccaaaa
    29821 gacaaaaaat tgctaaaagt tttaaaaaaa gaaaataatg agctttttga actagcgtca
    29881 aaagtaagtg aaaattatga ctatcaaaga cttttagatg tttataatta tatttttaaa
    29941 gaaattgaga caaaagaggt tataaaacta atcttctagt cacaaatcaa tggggggagt
    30001 ttaaatgaat aaagttgata aagaaaagat acaacatgca gtaagagaaa tactagaggc
    30061 aattggagaa gacccagata gagaaggtct aatcgagact ccaaatagag ttgctaggat
    30121 gtatgaagag atattctctg gtcttagtga agaaccaaga gaccatttaa aagttctttt
    30181 tgcagatgaa aaacatgaag aattagtatt ggtaaaagat attccatttt attcatgttg
    30241 tgagcatcat ctagttcctt tctttggaaa agctcatatt gcttatttac caaaaggagg
    30301 aagacttaca gggctttcta aacttgctag agtaatagat acattggcaa aaagaccaca
    30361 attacaagaa agaatcacta aaaatgctgc agatataata atggaagaat tacaacctta
    30421 tggtgtctta gtagtagtag aagctgaaca tatgtgtatg acaatgagag gtgtaaaaaa
    30481 accaggttca aaaactgtta catcagcagt gagaggaata tttgaaaagg acattgcgtc
    30541 tagagccgag gctatgagtt tgattactat gaagtagcaa tttattatag atataatcat
    30601 ttattgagat ataaaattta atttaaggga gtgtcattaa ttgtgtttga ttatggtaaa
    30661 agaacttata taatgggaat attaaatgta actccagata gtttttctga tggaggagat
    30721 tttaataact tggacatagc aatacaacat gcaaaagata tggttgacca aggtgcagat
    30781 ataatagact taggaggaga gtctacacgc ccaggtcata gctatgtaga ctcagacgaa
    30841 gagctaagaa gagtaatccc tgtaataaaa aaacttaaac aggaattgga gataccaata
    30901 tcaatagaca cttataaggc agatgttgca gaagaagcat taaaattagg tgtcactatg
    30961 gtaaatgatg tttggggtct tagaaaagat aaaaatatgg cttctgtaat aggaaaatat
    31021 gatgcagaag tgtgtataat gcataatcaa gatgggacaa actatgacaa agatataatg
    31081 gagtcaataa aagacttttt taaggtaagt atagaaatgg caatgagttg tggtgtaaaa
    31141 aaagaaaaaa tagtacttga cccaggcgta ggatttggca aggattttga acaaaatatt
    31201 gaagtattga gaagattaaa tgaattaaaa gatttagggt atcctatttt gcttgggaca
    31261 tccagaaaat cagtaatagg aaaagtactt ccagttgagc ctaaaaaaag attagaaggt
    31321 acaatagcta ctactgttct tggtataaga gatggcgtag atatagttag agtacatgat
    31381 gtttatgaaa atttaatggc agctagaatg actgatgcaa tatatagaaa gtaggtataa
    31441 tataatggat aaaatattac ttagtaatct aggattctat ggatatcatg gtgttcttaa
    31501 agaagaaaat tttctaggtc agaaattctt tgtcgacatg gaactttata ttgattcaag
    31561 agaagcaggt cttagtgacg atataaataa atctgtaagc tatgccgagg tttacaatgt
    31621 tgttaaagat attactgaaa ataaacaatt taatcttttg gaggctttag cggaaaatat
    31681 tgctgaagaa gtcttgaata aatttatact tataaatgga gttatggtca gagttagaaa
    31741 gcctgaggct cctgtaaatg gtatttatga ctattttggt gttgagataa ggagaacaag
    31801 agatgaataa ggcttatttg ggaataggta ctaacatggg tgatagattt gataatttat
    31861 caagagcatg tgaacttttg aaaaatagtg attctatata taaagtaaag gaatcaagtt
    31921 tatatgaaac aaaaccatgg ggatatacag aacaagcaga ttttctaaat atgtgtgtag
    31981 aaatagaaac agaatttgaa ccttatgagt tgttagaata ttgtcaagaa atagagagag
    32041 aactacacag agagagaata gttcattggg gaccaagaac tatagatgta gacatactat
    32101 tttttaatga tgtagcttcc actgatgaaa gactaacaat acctcatccg aggattcaag
    32161 atagagcttt cgttttgata ccacttatgg atttaaatga agaacttata ataaatgaaa
    32221 aaacagtaaa agaacattta aacctcctat ctgctgaaga aagagaagaa gtaaaggagc
    32281 ttgtaggtta tgaaagaaaa cctatttaat aataattcaa agatagagat aaatacaaat
    32341 aacaaaaaga taactgtaaa aaaagataaa cttataatag ctggaccatg tgcaatagag
    32401 agttatgagc aacttttgga gactgctaaa tttgtaaaaa gtcagggagc aaatatttta
    32461 agaggaggag cgtacaagcc aagaacatcg ccaaattcat ttcaaggatt aaaaaaagaa
    32521 ggtcttaaaa tattaaaagc agttaaagac gaagttggta tggctgttat tacagaactt
    32581 atggatgtaa gagatatcga cgaactgtat agtataagtg atataattca aattggttca
    32641 agaaatatgc aaaactttac tcttttaagt gaagtgggaa aacaaaataa acctgttatg
    32701 ttaaaaagag gaatagcatc cacaattact gaatggatag gtgcttctga atatatagca
    32761 atagaaggaa atagtaacat tataatgtgt gagagaggta taagaacgta caatgattat
    32821 actagaaata cattagattt agctgcggta cccattattc aaaaggaaac aggtcttcct
    32881 gttgtggtag acccaagtca tgccactgga gttagatatt tggtaaaacc tatgtcactg
    32941 gcatcttttg catgtggagc agatggaata atggtagaag tacatcctga cccagaaaat
    33001 gctttgtcag atggtgctca atctctttgt tttaatgaat ttgaagattt aatgaaatca
    33061 attaataatt attaaaagag gcaagagcct cttttttatt cgtaatcatt gctaaggtaa
    33121 atttataagt tataatttga tagttagatt atttaatata aataaagatt taatattgat
    33181 agaattaata taaaaaataa aaattttttg attaataaga aggatatcaa taaaaaaagt
    33241 cgaattgtgt atattgagtg attgacaaat ttagaatata gtgtagaata gaaatgttaa
    33301 cacaaaaaat tacaccagaa ggtgataata tgaatgatat aaaagacatt attgaagaaa
    33361 taaaagctag atgcgatata gcaagtataa tatctgaata tatgaatata aaacaatctg
    33421 gagctaatta caaagggtta tgtccatttc atggtgaaaa gacaccttct ttttatataa
    33481 atacatcaaa acagatttat aagtgttttg gttgtggtga aggtggagac gtaataaatt
    33541 ttgtcatgaa aatggaaaat ttggatttta tggatgctgt aaaaatttta gcaaataaat
    33601 gcggtataga aattaacact aacatgaatg aagaaactag gattaaaata gaaaaatcta
    33661 agaaatttca agatatccat acggaagcag ctagatttta tctttcaaac ttattgggaa
    33721 gcaaaaatct tgggtatgaa tatttaagaa taagaggact agatgataaa attattaaga
    33781 aatttggttt aggattttct ttggattcat ggaattcact tatgaatact ctaataagta
    33841 aaggatacaa aaaacaagac ttattggatt gcggtctaat tgcaaaaaat agagatggaa
    33901 ctaattgcta tgataaattt agaaatagag ttatgtttcc tatatttgac tatagaggaa
    33961 acataatagg atttggggga agagtattag atgattcttt gccaaaatac ttaaattctc
    34021 cagacacatt aatttttaat aaaaaacaga acttatacgg attaaatttt gctagaaaaa
    34081 atttagaaag taaaactata gtcttagttg aaggatatat ggatttaatt tcgctttatc
    34141 agtatggtat aaaaaatgta gtagcaaccc ttggaacagc cttgactgaa caacaaggca
    34201 ttttaataaa gagatatgcg gacactgcta ttatatctta tgattctgat gaagcaggaa
    34261 taaaagcgac tttaagagct atagatatac ttactaaatt aggtatcaat gtaaaagtgt
    34321 tagacttaaa agatgctaaa gacccagatg aatttgtaag aaaatacgga cttagtgatt
    34381 ataaaaaagc tatggatgtt tctactcact acataaaata taaaatagat catcttaaaa
    34441 aagaatttaa cattcaaaaa gatgaagaac gagtgaagtt cgcaaaagaa gcttctaaaa
    34501 ttataaaaca attgacaagt cctgttgaaa ttgattttta tacaaagtat ttaagcaatc
    34561 aaatagatat taatgtcgag tctataaaga gagaagttta tggcaaaaat tacaataagc
    34621 catataataa caaaaatcaa aagaaaatag aagaaaaagt aattgaaaaa gtcgaagtca
    34681 gacaagacgg aaaacaatta gttgaagaaa ctctaataaa aataatgtta gaagacaaaa
    34741 aaattagaga aatagcgtta cttaaagtag aagaaagtga ttttttattg aaagaaagta
    34801 aagaaatttt aaattacatg attaaaaatc aagaattgga caaaataact attgacaaat
    34861 tgaaaagttt aaacatatcc gaagaatact taaaagaatt aaattcaatt tctttgaata
    34921 gtataaactt agagaacaca aaagaaatag aaggaataat aacaaatatc agaaaaaact
    34981 cattagaaga gcaaattaat agcttgttga gagaacaaca agaattagaa aataataatg
    35041 atatgaaaga ggtagatggt agagttatgg aaattgcttt aaaaatagtt gagataaata
    35101 aaattttaaa gagcttgtag agaaaggagg tttgagtgtg gaaaataaat cgaataaaaa
    35161 agagttaaaa aaggttactg ctaagacatt aatagaaaaa ggaaaaaagc aaggttctct
    35221 gacacttgca gagataatgg aagctttttc ggagactgaa cttgataagg atcaagtaga
    35281 aaatctttat gagactttag gaaatttggg aatagaaata acagaaacaa aaaattataa
    35341 agctgatata gatttttcgg ttgctgatga cgatttaagt ataggccact tagatgaaga
    35401 tgcagaggca atttcacatg atgactcttc tgcaatagaa atagaaactg tggatttatc
    35461 tttaccaaaa gggataagta tagatgaccc tgtaagaatg tacttaaaag aaataggaaa
    35521 aattcctcta cttaaaccac atgaagaagt agaatttgct agaaggatgc acgaaggtga
    35581 tgagatagca aaacaaaggt tagttgaagc aaacttaaga ctagttgtaa gtatagcaaa
    35641 aagatatgta ggaagaggta tgcttttctt ggatttaata caagagggaa atttaggtct
    35701 tataaaagca gtcgaaaaat ttgactatac aaaaggatat aagtttagta cttatgcaac
    35761 atggtggata agacaagcta taacacgtgc tattgcagac caagctagaa ctataagaat
    35821 accagttcat atggtagaga ctataaataa gctaataaga gtatcaagac aactacttca
    35881 agaacttgga agagatccaa aaccagaaga aattgcaaaa gaaatggaaa tgacagaaga
    35941 taaagtaaga gaaataatga aaatagctca agaccctgtg tctttagaaa caccaatagg
    36001 agaagaagaa gatagccatt taggtgattt tattccagat gatgatgctc cagccccagc
    36061 agaggcagca gcatattctt tattaaaaga acaaatagaa gatgtacttg gttcgttaaa
    36121 tgatagagaa caaaaagtat taaagcttag atttggtctt gaggatggta gagccagaac
    36181 tcttgaggaa gttggaaaag agtttgatgt aactagagag agaataagac agatagaagc
    36241 aaaagcacta agaaaactaa gacatccaag tagatcaaaa aaacttagag attatttaga
    36301 ctaaaaagat acatcattga tgtttttgtg ataaatgcca tgagataagt gatatctcat
    36361 ggctattttg tagtaaagat ttaattttat ttttgtagtt atttcagtct aatatctata
    36421 acttggatta aatcctataa ataaagggaa ttgaaaggag aattatattt gaaattaaca
    36481 gatagattat tgaaaatagc atcattagtg tcagatggta aaaaaatagc tgatataggg
    36541 acggaccacg gatacatacc agtatatttg ttaaaagagg gaaaagtacc atttgcagtg
    36601 ctagcagatg ttaataaagg acctcttgac aatgcacata aagaagtcat acagaacaat
    36661 cttttagata aagttgattt acgattgggt tctggtatag agatacttga aataggggaa
    36721 gtagaagaag tgataattgc tggtatgggt ggaatcttga taagtgagct tctcgaggct
    36781 aaaaaagaag tagcacataa tgtagaaaaa ttaatattac agccaatgca agcacaagaa
    36841 gaacttagat attacctttt aaacaacgga tatgaaattt tagaagaagt tttagtgaga
    36901 gaagatttta gaatatatga gataattgtt gccaaatata caggtaaaaa tactataata
    36961 gaagatgaga tatattatga ggttggaata aagcttttag aaaacaaaga ttctcttttt
    37021 aatgatttta tagaaaaaaa gataaagaca tatagttcta tagttaataa attagaaggg
    37081 aaaaatgggg aagctataga taagaagaga aaggaaagcg aagttgcaat aaaaaaactt
    37141 gaaaatttaa taaaataaat aggaggtata tatgctatta aagagtctaa ctagaaaaat
    37201 tgaaaaaaag tatcctctaa acttagcaga ggattgggat aatgtaggtc ttatagttgg
    37261 agattttgat atggatgtaa aaaaggtatt ggtatcttta gaagctaatg aagatgttat
    37321 tgatgaagct atatccaaaa atatagattt aattgtgaca catcatcctt ttatatttgg
    37381 gaaaattaat aaaattaata gtggagattt aaaaggcaga cttatccaaa aacttattaa
    37441 aaatgatata tcactttatt ctatgcatac gaattttgat atagcatttg atggtctaaa
    37501 tgactatttt atggaaatta tggaatttgg taattcaaag gttttagata taactaaaag
    37561 cgaaaatttg tataaattag cagtatacgt tccacataac tattcagatg aacttagaaa
    37621 ggttttaagt aattcaggag caggtcatat agggaattat agtgattgta cgttttcaat
    37681 agaaggtgaa ggacaattta agccattaga aggctctaat ccgtttcttg gaagtgtaaa
    37741 tgatatagaa actgtaaatg aagttaaaat tgaaactgta gtaccacaga agcttttagg
    37801 tggggtaata agttctatgt tagatgcaca tccttatgaa gaagttgcat atgatttgta
    37861 caagttagaa aataaaggtg agatatttgg actaggtaga ataagtaaac ttgataaaag
    37921 tatgacatta gaaagtcttt caaggaaaat aaaagagaaa ttaaatatga aacacataag
    37981 agtagttgga aaccttagta cagacataac gaaagtagcc gttgtaacag gagctggttc
    38041 agaatttgta aaaaaagcta agagacaagg tgcagaagta ctaattacgg gtgatgtaaa
    38101 gtatcatgag gcacaagatg cacttgatat tggaatgtgt atagtggatt gtggtcattt
    38161 tgatacagaa gatatattca aaaatgttat gaagagattt ttagatgaat ttagtgaaat
    38221 tgaagtaata aagagtaatg tatatttgaa tccatttagt actatttaga agtgtttgat
    38281 taaaaaatac tatataaaaa ataaatttga gtttaattag ggggataatg atgaaagtag
    38341 cagtaatttt tcatagtgtt tgtgggagta catatttatt agctagagaa tataaagaag
    38401 tgcttgaaga aatgaatatc gaggtagata tatttagagt aagtgacgaa gttgcaaaaa
    38461 cacttcctca atattatttg ataaattaca aagaatacaa agacgaattt gaaagtataa
    38521 atgtaattaa atctggaaaa gaaatattag attatgatgc tatatttatg ggttcaccaa
    38581 catattatgg aaatgtatct ggaccaatga agatgtttat ggatagtttt tctgatattt
    38641 gggtaggtgc tcctttgagt ggtaaaatat ttggttgttt tgctacagca ggttcacaac
    38701 atggaggagg agaattagct ttgcaagcta tgaatatatt tgctcaacat atgggaatga
    38761 ctcttttgtc agttccatgt tcagtaagag gaggttatcc agcgtatgga atacttcata
    38821 tagcaggaga taattctgat ataagaccaa atgatgatgc caagataggt ataagagatt
    38881 acctaaaaag acttaacata taagaatatc atataaaaat acctaaaagt agctgtatat
    38941 acttttaggt atttttactt aattatatac gtgaagcttt accagaaata tggtcaattt
    39001 ctattttaac aacagttgtt aagttcatat ccttctctat gtacttcatg ccttcttcaa
    39061 agaatccttt agaatatttt tttattattt ctacaagagc atttttcttt tcttcatttt
    39121 ctacagtgca agcttttcca aaaactatag cactagaata agtagtacta aatttatctg
    39181 gaataacact ttcattagca actactaaaa aagaaacttt gttgtttttc gatatattat
    39241 ctaacttatg tccatttctt gcacaatgaa agtaaataga atcattaaag tatacataat
    39301 ttacagcaac tccataagga taaccatttt cagatatagt ggaaaaagta ccaaattcac
    39361 cattttttaa tacttcaaca gtatcttctt ttgtcatttc tctttttttc aatctcattt
    39421 ctttaaacat aatatcatcc tttctaattt tgatgcttaa attaaatttt agcacattta
    39481 taaagattat gctatgtttt ttacaaattt taagaaaaaa atatagttta agataaaagg
    39541 tagtgaaaga gaagctattt ggaggtttat ttatgatatt attgttagag tagtacaaac
    39601 aatactaata aatttaatag ctggtttctt gttatttaag gtagtaagca tgtctataag
    39661 aaggggaagt tatcgagggt agaagttgtt atttataacg atattataaa gaaaatatta
    39721 ttatataaaa taataaatag taaagaggta tcaagttgaa tataatactt aatacctctt
    39781 caaaattaaa ttataaaagt gttgtgggaa ttgtcctata catggtaagg agataataaa
    39841 gaatgtatct ttaaagtctc aactaaacag caaaatttat ccaacaaaca tacaataaat
    39901 gcttctttgt atctaggtgg cttaacagta agtggccaca tgtgttttaa aattatgtcc
    39961 gtttcttttt catttatttg aaaaaataaa gttgcatttt ttaatgcttc tctagggtga
    40021 gtaaatccat gtaatccttt tctatcacct ttgtaatgcc aatcataaag aaaaaagtcg
    40081 tgtagtaaag ctcctctaat aacactttga atatcaacac gtaagtgcaa ttttttacat
    40141 aatagataac tataatatgc tactgacaaa ctatgttcaa gacatgaaac attgccatga
    40201 tgaggaaatg ttctcataag ttgaactttt tcagaagaaa gtatctcaga agcacattca
    40261 ttaaaatatt tgatttcagc ttttgacaac attatgaaaa tctccattct tagtaatata
    40321 taaatactat acttcaacga taatatgaaa tatttcttat cctacaaaat ataataccca
    40381 ataatacaag taagatacct tttatggtat tttaaagtaa gagagatttt attaggctaa
    40441 acaatgaaaa aattaaaagt aaagctatag caatatatag tatttttcca agaggattgc
    40501 caaaatttat agtccatcca ataccaaacc ttttattaac cattaatgat gggtcatttg
    40561 gattattata catgatgcct gctatccaat acttctcatc ttcttctgga gaataagatg
    40621 agttgaattt taaatttggg gaattaatat atgttgctat taaataaatt ataactaaaa
    40681 gcgttgtaat attcatagca gttgatagtt ttgtttttat tgataaaaga gtagtaaaaa
    40741 actgtgttgt cattataatc atcaatatta aaaacaaata accaatttta tttaaatatt
    40801 taatgttttc aactctactt tcttcaattc tatttgtatc tatcttaatc cttgacttta
    40861 tggatccaat ggaagttata tataataaaa ccattaaaca aaagtcagta ccgattaatt
    40921 taaatacatt aagaaatgat ttatctataa aaacatcagg agacccattt atgttccaat
    40981 gagtggcaat tgagtctggc aatttattat aattaaatgc tataaaaata ctcatcccca
    41041 aagtaaatag tatcggtatt aaatagatta ttttaaattt ttttattatt ttatttttct
    41101 tatttataaa atccatatct actattaatt ttgaatctac atctatatga cctaatttag
    41161 aataaatttc tgatttaagc ttcttagctt ttttatgtgt atgaatatat agtatactct
    41221 catataataa aaaacctata ataccaataa aatatgaaag ttccaattta ttaaatgtaa
    41281 aaaccagaat aaaaactaat ataaagtcta taataaaacc taaagataat agttttttaa
    41341 attctttatc taattttata aagtaattat aatttttatg ctcttggtct atagaaactc
    41401 catagatgtg ttttttacct acaaaatagg gcataaaata aaatgtagca tacatcaaaa
    41461 ttagaactgg aaatattgta aatagacatt caatcttact cataatattt cacctcatac
    41521 ttgtcaaata aacttgaact tagtgacaaa aattcttctt tactaatacc tgataaataa
    41581 gattttgcca ccaataattc caagtcaagt ttattttttt gacgagttgt attatctatt
    41641 ttcattggta gttgagctac aatagcacct tttcttctat caatatttaa gaatccctct
    41701 tcttttaact cattgtagga tttgttcact gtatgtaaat ttacaccaat attttctgcc
    41761 atacttctta cagatggaag tgattcattt attttcaatt ctcctgaagc tatagcctta
    41821 gttatttctt ctttaatttg tacataaata gatttatcac tattaaaatc taaatttaaa
    41881 accataaaaa acctccatta tgctttataa atgaaaacga ttgttatata catagtataa
    41941 cataaaaaat aataacaaac acaaaatata agtttatatt ttgtaaaaat tgtaatttaa
    42001 aaaataacat aatttttatt aaaataatac agatactatt tatagataga aataaaaatt
    42061 agaaaggaga aaaaatatgt taacatattt aatgaaaaga caaatgcata aaaaagatga
    42121 tggaatgagt aaaccaatga tgattacagg agctgtaatt acaggtgtag gagcatatgc
    42181 tgtatacaaa atggtaaaaa gccataaatc taattctcaa atggtcaata caaattatta
    42241 tggaaatagc gattatgatg attataaata tgacgaattt gattatgact gtgattgtag
    42301 agacacaaaa caagattatg aatatgaaga attaaaaaaa aaagtaaaag aatttaattc
    42361 aagaagaata aattgtgaaa attgtccaca tgtttctcaa gaagaaatga tgcaatatgt
    42421 aaatagtgtt aaagatgtaa aggaagatat tgatttacat gaagatgcta aaaaagataa
    42481 tatttacaaa gaagatgaat acaaaaaata tgaagaagaa taagtaatat tttgtataac
    42541 tgaacaaata gtaatgtcaa attatttaat atctagtttt aatatgtaag ttgtaactta
    42601 acttgaaaga atcagtatca ttctttagat agttaagtta caacttacat tttgttttta
    42661 taaattttaa tagttctttg tgactatttt gtaattttag aaatatttta gtatccaggg
    42721 taattgtgta taataaaact tgtatagata gatagtatga aattaagcag atagtttaaa
    42781 attaaaatga aaagaaagga aatagttatg ttaaagttgt tgatagttga agatgatagt
    42841 actatatctt ttggaataaa gtatgcttta gaacaagaag gatttagtat agatatatca
    42901 aaggatttat ctagtggaaa agaaatgatt tcttctaatg aatatagcat gatactgttg
    42961 gatgttacat tgccagatgg aactggttat gagctttgta aatatataag aggattctct
    43021 caggttccta taatattctt gactgcttgt gatgaagaag taaatattgt aatgggtctc
    43081 gatataggtg gagatgatta tataacaaaa ccttttagaa ttagagaatt aatatccaga
    43141 ataaaagctg ttttaagaag aaaaggtaat acttcagaag aaaataagaa aatacttaaa
    43201 tttggagatt taagtatata tacattagaa gctagagtat ataaaaatga taaagaaata
    43261 tttctgacat cagttgaata taaacttctt ttaattctta tacagaataa aaatactgtt
    43321 ttaagtagaa ctcaaatatt ggaaaaactt tgggatgtaa cttatgattt tgtaaacgac
    43381 aatactctaa ctgtttatat aaaaaggctt agagaaaaaa taggtgatga tttatgtgaa
    43441 ccaatctaca tagaaactgt aagggggatt ggttataaat ggataggaag tgaaaatagt
    43501 gtttctatat aatccagaag tgaagaagtt tttaagtaag tatgttactt tgatgtttat
    43561 tgttatcata atatctattg gatttagcat aatcaacgtg tctttaacta aagagatggt
    43621 tgtaagaaat aatcaagcta taatagggac tttatcgagt aagtatccaa acttagaaag
    43681 tcagatagta gacataataa ctcaagggaa gtctatgaag aacatagatt atggtcagaa
    43741 aatattaagt aagtataatt atgataaatc tattaagata aactctgagc ctattatttc
    43801 taaattagtt ttagagacta tcaaaataaa tataatatta gtatgtataa tatttatttt
    43861 gatatttgtg ttggttgtta gatattttac gtcaatttac aatgatttat cagatatgac
    43921 taagtatgtt tactatagtt cagagggtaa gccatttgat atgaaaaaca agaatcaaga
    43981 agggcagata ggtcttctaa aaactgaact cttaaagatg acgacaattc ttaatgaaaa
    44041 ggttgaactt ttaaaaagag aaaagatatt tttaaacaat acaatttccg atatatcaca
    44101 tcaattaaaa actcctatga cttctttaat aatgttgaat gatttattat ataatgatgt
    44161 accatacgaa gtaaaaatcg attttttaaa taagataaaa aatcaattaa atagaatgga
    44221 ttggttgatt aaaagcatgc ttaaattatc aaaggtagaa gcaaaagtga taaattttaa
    44281 aaaagataag gtaaaattta gtgaactcat acatagagca atgctatcta tgaaaatacc
    44341 tatggagatt aaaaatcaaa aactgactat agagggaaat gataatgtat cttatattgg
    44401 tgatattgat tggtctgtgg aagcactagt gaatataatc aaaaattgtg tagaacatac
    44461 tcctgaattt ggaaatataa ttataaccta taaagaaaat ccattatttt ctgaactaat
    44521 aataaaagat gagggtgaag gtatagataa aaaagatata ccacatgtat ttaaacgatt
    44581 ctatagagga agaagtagtt caaaagaaga tagtgtagga ataggtcttg caatgtcaaa
    44641 atctataata gaaagccaaa atggcgatat atatgtaaac agcgaaaaag gtaagggtac
    44701 agaatttcat ataatatttc ataaaatgta tgatagtgac taatctgtaa tatttaattc
    44761 actttatagt aatagccaaa acctaatata tgaagtatag aatataaata ttggaggtag
    44821 ttatggaaat tttaagagta gaaaatctaa ctaaaagtta tggtaaaaat gaaacaaaag
    44881 ttgatgctat aaaaaatgta agtttatcag ttgaaaaagg aacgtttata gcaataacag
    44941 gtccaagtgg aagtggtaaa agtaccttat tacatttatt aggaggagtt gacagaccaa
    45001 ctagtggtaa ggtttatata aatgatgttg atatatataa tttaaaaact aaggatttgg
    45061 cgatatttag aagaagaaat ataggtctta tatatcaatt ttacaactta attccagtct
    45121 taaatgtgaa ggaaaacata ttgcttccag cagagcttga caatagagat attgatagag
    45181 aatattttga tgatttaatg aaaacattag gtctaattga tagagaaaag caccttccaa
    45241 accaattatc aggaggtcaa caacagagaa cctctatagg acgtgcatta attaatagac
    45301 cttctataat attagcagat gagccaacag gtaatttaga tagtaaaaat tcaaaggaaa
    45361 tattagaatt gttaaaattg tcagtaaaaa aatacaatca gacactaata atgataactc
    45421 atgacaaaaa tatggcactt caagctgata gaattataag catagaagat ggaatcataa
    45481 aaagtgatga ggtgatgtag atgaatttat atacatcact aaccattaga tacttaaaac
    45541 aaaataaaag aagaaccatt gtaaccataa tcggtataat actttcaaca gctttaattt
    45601 gtggtatagg aaatatattt gaaagtttta tggattatca aatgagagaa actataaaga
    45661 atgatggaag tttccatgtt acattttatg atgtaaatag aaaaaatgtg gaatatgtaa
    45721 cgaaatcagc tgaaatagaa aaacatgcat ttaccaaaca acttggatat tctaaattag
    45781 aaaatagtga aaatgctata ttaagtataa agcaatatga tcaaaatgca ataaacggat
    45841 ataaagtttc tataaaagaa ggtagatttc cagctaagga aggagaaatt gttttaagtg
    45901 aaagtattat taatcttata gatgataagt taaaaatagg agataagata actttaaaag
    45961 taggggatat gtttgactca agcaagaaaa agattgatag tatgacattt catgaaggtg
    46021 attatatagc aaatgaaaaa gatagaactt ttaaagttgt tggtataatt aaaaaacctg
    46081 ggtttgaacg ttataatgga attgcaacag ctatagccta ctttaatcct atgaataatt
    46141 acaatgatac aattaatgta tcagtagcag taagaaatcc taaagatgtg tataagataa
    46201 gtaataaaat aagtaaaaat atatattcaa ataaagataa agaagcagtt tctgatatga
    46261 taaaatacaa tgaacattta ttgaggttac aaggtgctag taagtattca aatataaata
    46321 gctctataaa gtctataatt atagcagtaa ctattttagt aatcatatgt acaattgcta
    46381 cagtgtacaa ttcctttagt atttctataa atgaacgaaa aaaacagttt gggatattaa
    46441 attctatagg tgctacatct agtcaaatta aaagattagt ttttatagaa ggtattataa
    46501 ttagtttaat tggtatacca ataggactaa tatctggaac agtagctata gacctattgt
    46561 ttaaaattat aaataagtat tttactgaat cggttgttac taagatgagt ttgcagatag
    46621 tgtataatcc aataataatt attgttagta taataatagt tttgcttaca atctttatat
    46681 caattctact acctgcaata tcggcttcta atatttctcc ccttaatgtg attaaaaata
    46741 ctggagagta taaagtgggc aaaatcaaaa gctcaagact tattaaaatg atttttaaaa
    46801 ctgaaggagt acttgcatat aaaaatatta ggagaaatag aaaaaaattt ataataactc
    46861 ttttttcttt aatggtaagt ataataatat ttatatcttt tagtggcttt acattacttt
    46921 tactaagagg tgaagaaatt agaaattctc aaagaaaata tgatttgtat ttaactgcaa
    46981 agaacacagc taggtctgta gaggatacta taagtgaact agaagatatt gatgggataa
    47041 aaaactttga attggcaaca ggacaatatg tgtctataag agtaagtgaa aataaaataa
    47101 ataaatccaa ggaagattta atcaggaaat attatcaaaa atataagatt ggagaaagtt
    47161 atgaatatga tttcagtaat aatgaattga tttttccggg agattttgca gtaaaaaaca
    47221 aaataaataa cttagtacag ggctctttta ataaagagag agcaattgaa gaaaatggtg
    47281 ttatattagt tagaaaaagt gcaattgaag aaaatgggaa gaaaggtgta gtagaactta
    47341 ccaactataa agtaggagat acagtaaatt gtgaatatct tgatgaaaat gccttaagta
    47401 aaaaagtaaa ggtcaagatt cttgctataa ctgatgaaga acgtctaggt tttggttatc
    47461 aaaatatggg gttacaattt ataacttatg atgaagttgc taaaaattta aatttaaaat
    47521 taagtaaaag ccttatattt attgattcag gaggaagcat taagactaag aaggaaatag
    47581 aagctttggc aaataaaaat gattttaact tttatgatga aatttcaagc agtgaaagtg
    47641 aaaaacaaga tttaaaggtt attaaaatat ttgtatatgg ttttatagta gtgatatctt
    47701 tagtgagtgt tacaaatatt ctaaatacag taagtacaag tataaatcta agaaaaagag
    47761 aacttgcagt aatacaatct ataggggtta ctcctaaagg atttaggaaa atgatatatt
    47821 tagaaagttt tatatatggt atactgtcat tgttgtttgg aataccaatt agtattggta
    47881 taattctaat tatgaataaa cttatttcag gtgtaattga attttctccg attataccgt
    47941 ggacagccat agttatctgt atagtaagtg tttttataat aacttttata gcagggtata
    48001 taccaatgag taaattaaat aaagaaaata taatagataa ta
//
LOCUS       DAMJYN010000024        47209 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.024, whole genome shotgun sequence.
ACCESSION   DAMJYN010000024 DAMJYN010000000
VERSION     DAMJYN010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 47209)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47209)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47209
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.024"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            <1..449
                     /locus_tag="PC466_001451"
     CDS             <1..449
                     /locus_tag="PC466_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF2768841.1"
                     /translation="KQEPCDFSHGRFRFGGKIIRRNEKTKFDWLSRDKEQVEKYINDP
                     FCGVVCSCGFFYDLVQGLKEIEDKENLKKVPLDIPIYIISGDKDPIGKNGKGVLRLRD
                     RYIKLGVKDVTCKLYKDGRHELLNEINREEVFEDIICWLNNKIEIL"
     gene            914..2128
                     /locus_tag="PC466_001452"
     CDS             914..2128
                     /locus_tag="PC466_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2768842.1"
                     /translation="MQIKIGKVIQRLRKERNLTQEQLAKFIGVSTPAVSKWESGNSYP
                     DIELLPLLADFFNVSIDKLLNYKIDLSEEKVMKIYKELESGFARIEIDLSTEEPKEEF
                     RQDLESVKKLSNMYIEKYPKSYLLKLRICSLYQMYSYKFGKSELNDRVKETTNILEDI
                     VRNTDDIQIKETALIILSNAYCMLEDYEKAELYLNMIHKSIGDTSVNLAMIYLKQNRL
                     EEAEILLQNKLFSNIFNISMDCKGIINVYKNQYKELKKKLENRNFNKNAIEREMEYIK
                     NKLLWYANLSLEIKKMLSEDKGAFFSMYVDYMELSLIFLFFNMKEEAKKALYSLKEIL
                     EKYPIHESLDVSQMRFFDKVESKNLYTFNIYTNLLIVLNDDSYNELREEPIFKDVIEK
                     ILDMEKMLKNKE"
     gene            complement(2548..3069)
                     /locus_tag="PC466_001453"
     CDS             complement(2548..3069)
                     /locus_tag="PC466_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2768843.1"
                     /translation="MKFERLRTSENKLYYKAMELYKISFPFHEQRKSYLQTEILKNKE
                     YQFNLIYDKNQFVGIILCWETDNFIYVEHFCIFPEMRNNRYGQRALELLNKKGKTIIL
                     EIDLPIDEISIYRKAFYERVKYKTNNYEHIHPPYHEKFNGHNLIVMSYPEKLSKMEYD
                     KFNHYLRNNVMSF"
     gene            3425..4222
                     /locus_tag="PC466_001454"
     CDS             3425..4222
                     /locus_tag="PC466_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HDF2768844.1"
                     /translation="MEKREKRIIISSLLSVSILMGLVSIYSILNKEDIILTVKGQEQK
                     VSSFKKTVEELLDEQGVKYNSEDKINPSLDTELKDDMKIKVVKVTKSKKEEIEKIPFD
                     TKHVNDSNLLKGKSKVYQEGQEGEKKLVYNLTYHDGKLVKKVLSKEVISKEPTTKIIK
                     YGTKEKVLIASRGANIRGGKHMKVVATAYAGDTITSTGTTPRWGVIAVDPRVIPYGTK
                     VYIPKLGMTFVAEDCGGAIKGNRIDIFMNSEGKASNWGRKSIDIYLH"
     gene            4332..4922
                     /locus_tag="PC466_001455"
     CDS             4332..4922
                     /locus_tag="PC466_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HDF2768845.1"
                     /translation="MKIVCLGDSLTYGFGVSRSNSWTNIVNEETRLEIVNKGINGDTT
                     SGMLARFNEDVVKNSPDIVFIMGGTNDFIAGAGNEIINSNIMAMVHQSYSKNIIPIIG
                     IPLKPDIPNVREDWSCFTDFNIVSQNLESYSYWIKKFCMTFNTNFADFYSEYNKNMEL
                     EGYKKLYFDGLHPTKEGHRIMADIFINSINKYIEEL"
     gene            4988..6685
                     /locus_tag="PC466_001456"
     CDS             4988..6685
                     /locus_tag="PC466_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HDF2768846.1"
                     /translation="MDYTKTYEEWIKGSYFDEDTKLELENIKNNEKEIEDRFYKDLEF
                     GTAGLRGIIEAGTNRINKYTVRRATFGLANYILENTTKEETSRGVVIAHDNRHKSRQF
                     CIESANTLAACGIKAYIFDSLRTTPELSFAVRSLNAIAGIVITASHNPPEYNGYKVYW
                     EDGAQVMPEIANAITEKVNSIHDYSTIPTLTEANKNLVVLLDESQDTKFIEAVKSQII
                     RKDLVKNVGKSFKIVYTPLCGTGNVPIRRALKEVGFENIIVVPEEENPDPNFAGLDYP
                     NPEEKKALNRGILLAKEKGADLVIATDPDCDRVGVAVKTTTGEYALLTGNQIGGMLTH
                     YIIEGLKENNKLKENPTIIKTIVTSEFGADIAKANNVDVLNVLTGFKFIGEKIKLFEQ
                     NKNRSYVFGYEESYGYLVGTHARDKDGVVSSLLISEMAAFYYSKGISLYDGLIELYKK
                     YGFFKEQTISLTLKGIEGVEKIKEIISYFRENQIDYINSIKVVDKKDYKNGIDNLPKS
                     NVLKYFLEDESWVAIRPSGTEPKLKFYIAVKGASDIEADKKIQGLKKYIDDMVEKLK"
     gene            6899..7738
                     /locus_tag="PC466_001457"
     CDS             6899..7738
                     /locus_tag="PC466_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HDF2768847.1"
                     /translation="MFGIDKKLIEYIIAKSNYSELSSKSAEVSFFLMLSIFPFLIFTI
                     SSIAYIPILHLNKYIALFRNMMPEGAFAVLSSIIVSAIDNRNLKFLAVSFVLTMWTFS
                     RAVKALIKGMNRAYKVKETRSFFKILSISFLFTIMLLVLIFLSMIFLVYGEKIGYFIF
                     NLVGLDEIFIKIWDILRYTVGIITIIVIFTLLYKYTPNKKLTIKESAPGAIFATFAWF
                     LVSFLYSYYTNYYANYEVIYGSIAEIIVLMTWMYFSSWSIVIGYEVNSRLYFRKIRHE
                     MLK"
     gene            8255..10111
                     /locus_tag="PC466_001458"
     CDS             8255..10111
                     /locus_tag="PC466_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing protein"
                     /protein_id="HDF2768848.1"
                     /translation="MDIHNKYVNFIKNIPVPFLYCRIVKRQEDIEYRVEYISKGMGKV
                     LQLEEGICDKNILDVLPVFKSKKYFKELFSNEVDCIKRYIPTLKNWINIKKQIIGDSY
                     IILYFGKIVFDYRQIIDSFDKKEKVAYIKDEEGIYIDCSENLIPILNNNIKTTKDIFG
                     KNDIEVWGENTGKLFRDDYRGGVSSKKRFLQNLFEYEETFFMVEKYFLYDEDELLGTI
                     GIIDNIIYSGYSNRNYNSKDLMKMIEHSIPENMFYKDVYGNYIGFNSGFLNLACMNKE
                     ELLGKNSYKISEEEALINKIFESDKGVVENKKVVTFELNVSINDENKCIEITKRPFFD
                     SYGSVIGIIGTARDISRRKRLEEEMDKTRMEFFANLSHELRTPINLISSSLQVIEKKE
                     ADLIESNDTLKRNLGIIKQNGNRILRLVNNVIDFTKMQSGYLDFKPEESDIIAFIEEI
                     CMSVADFASQNNIQLTFDTEIEEFSMLFDSEKLERIILNLLSNGIKYNKKDGKINIFL
                     YVKDNVFNMKISDSGIGIPKEKIDKIFNRFEQIDNELSYRVKGSGIGLSLVKSLVELH
                     EGSISLKSQLGIGSEFIVSLPVRSENNIEKYNHKREISNELSKKLEIEFSDL"
     misc_binding    10194..10434
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    10500..10735
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            10820..12037
                     /locus_tag="PC466_001459"
     CDS             10820..12037
                     /locus_tag="PC466_001459"
                     /EC_number="1.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HDF2768849.1"
                     /translation="MENKVKIGVLGYGVVGSGLIDIIDNNKEKRSIEIVGILVNNLEK
                     HKDKKYSNIITNNIDDIFNKDIDILVEVMGGLEPSLSYIKKALNNKIHVVTANKDLLA
                     ECGDELAKLASENKVSIKFEASVAGGIPVLKPIIESLEGNNIDSINAILNGTTNFILS
                     KMYDENLSYDMALRQAQELGFAEANPESDVLGYDAARKLSILSTLAYDNRVYWKDVYL
                     EGITDIDEKDIEYAKKLNCKIKLIGQSKYENDKVSAFVRPVLVEKDNILARIDNEFNA
                     VIVNGDSVGEVSFVGKGAGSLATGSAVYSDVIDIIDNRVSSIDSFTKDKIQVNKIVRE
                     KCGALLRFKKCNKDEILNIVENCLVKFDILNDDDELAIMVYADSEYEINNSLCLIKDK
                     GYCEKMNKMLKIS"
     gene            12151..12645
                     /gene="cdeM"
                     /locus_tag="PC466_001460"
     CDS             12151..12645
                     /gene="cdeM"
                     /locus_tag="PC466_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exosporium morphogenetic protein CdeM"
                     /protein_id="HDF2768850.1"
                     /translation="MENKKYANGGYSEDWYERGESTAKWFQNDREEYERAAYDEDRER
                     RGSNCGCSDSGGNRPRNCERFRREAEIREREAREAFCESSERKKEALAYECEARKLWE
                     EAEKYWDEYSKYNYKGIEYLAEAARLFDEGMECEARRNGNNGGNNNNCCHKCHKCNCN
                     CCRK"
     gene            12910..14175
                     /gene="hisD"
                     /locus_tag="PC466_001461"
     CDS             12910..14175
                     /gene="hisD"
                     /locus_tag="PC466_001461"
                     /EC_number="1.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol dehydrogenase"
                     /protein_id="HDF2768851.1"
                     /translation="MKSIKTSSMKEKVDEKILREQVSSIIEDIRNNKDVALKKYNEKF
                     DRNTRDEFRITKEEIKEAYKHVDDEFINNLKIAAKNIREFAKAQKLSFENPFEKEIYP
                     GVILGQTNIPIESCLAYVPGGQYPLFSTALMLIIPAKVAGVKRIVACSPTMKNTEKIN
                     PKTLVAMDIAGADEIYATGGVQAIAAFTYGTEKINPVDIIVGPGNKFVTEAKRQCYGQ
                     VGIDFVAGPSEVLIIADETSNPVYIAADLLAQCEHDLNARGILLTNSLEVAQKVEKNI
                     ESMLKDLPTKDIAYSSWENNGEIILVDDMEEAIKISNFYAPEHLEVAVNEYNDICDRL
                     TNYGSLFIGNLSAEVFGDYVSGTNHTLPTLKASRYTGGVWVGTFIKTCTKQIFNEKAI
                     QSLAPVAEKLAKEEGLYAHAKAAEVRFKK"
     gene            complement(14378..15130)
                     /locus_tag="PC466_001462"
     CDS             complement(14378..15130)
                     /locus_tag="PC466_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF2768852.1"
                     /translation="MSYFQYQGNSCFYKEYGQGKPIIFLHGNTGSSNMFKALVPLYVE
                     NFRCILIDFLGNGQSDRVSQFSPDIWHDEALQTIALIEHLNCGKVGLIGTSGGAWAAV
                     NTGLERPDLVEAIIADSFDGRTLNDNFIDNLITGREKSKQDIQARKFYEWCHGKDWEN
                     VVNLDTKALLQCANKKRPLFHKELCKLEMPILFTGSKEDEMCRHNLEEEYKQMATFIS
                     KASIHIFSQGGHPAILTNADEFAQLAKVFFKY"
     gene            complement(15248..15517)
                     /locus_tag="PC466_001463"
     CDS             complement(15248..15517)
                     /locus_tag="PC466_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768853.1"
                     /translation="MSYQNSIDLLPKELIEQVQEYIDGKVIYIPKKQEHKKHWGENTN
                     TKQVLASRNSQICINFQNGMSIKQLSEKYFLTEKSIQRILKQQNL"
     gene            15992..17086
                     /locus_tag="PC466_001464"
     CDS             15992..17086
                     /locus_tag="PC466_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HDF2768854.1"
                     /translation="MKNIVGKPQTIKKVNEDLIKNIIKNEGPITKPEISSITELSLAT
                     VNKIVEQLALKNEVKVSGLSESTGGRRAQLFEINANLEHIIALYYYRNCCIGVVANLL
                     GEIIYQEEFNIRMDTYENVNQDTFFVIDTLIKKEKGNNIRAIGIGVPGVVKKGVVKNI
                     PTIKSWEGINLENLIKSKYNTKVFIENDTNITTIGIYQKQYKDKYKNMALMYLEDGIG
                     SGIVINGELYLGSTNFAGELSYLNIEFGKYNSNNLNLEDYIMSLRKRYLESKDNKFKK
                     EILSIISNFIRTLVCVLNPQAMIIQCSILTKSDMEFIEKDVSNNVGEENFPKLIKVES
                     LRERSINGVISMCLKETDYQYSLSNKKGGY"
     gene            17088..18038
                     /locus_tag="PC466_001465"
     CDS             17088..18038
                     /locus_tag="PC466_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine kinase"
                     /protein_id="HDF2768855.1"
                     /translation="MKYLVSIDGGGTKTKFCVSDLDGNILKEHTTGSTNYKSVGIKKT
                     YENINNGLKKILKDLYIDYDDIEYTVFGISGCDSPNDYKIIMDEILKIGINKEKIYLA
                     NDAVLAFYAQADSPGLVIVAGTGSIILGIKEDGEIYRVGGWGYNFSDLGSGYDIGRKL
                     LKKVLLYCDECHEYSDLFSCVLDFFGANSFEQLAYMITDINNNVEIANLASLVIDCAE
                     QGDKLAIEILRESSTELSKLAQVILRKISNPMKIDKSEINIVLSGGTLNKTVYAQMLM
                     NNLKTENTDKNLKFISQENQPVYGGIRLAMALANRRVKHG"
     gene            18031..19215
                     /locus_tag="PC466_001466"
     CDS             18031..19215
                     /locus_tag="PC466_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768856.1"
                     /translation="MDRKKVIVQIFTGGFKAKEIKFNDIKCKLLELLDCIDIEKVIMG
                     WSVDEELYVETKKLLNKYNVELYLWLPCFSEIGLLEKSNLLIDYMGKEVKGYALQEDE
                     NFEFYCPNNKENIKNIKKIYSTYFSDIKFDGIFLDKIRYGSFSNKLNGVFNCFCKDCL
                     NIYEKNNIDKKSLMREMNNVSKGVIDNEDTPSGITEYINGKYKFKNKIWEDFFETKNQ
                     NIYKSLLEISSYFKSKGLKIGIDTFSPFISYFTGQDLKKLQEVADFIKPMMYRTTKAP
                     AGLPFEFERFIDESIHKNKEIGKRNFLDILGIKEYEGDVYPIEFVLEEIDFMTRNLNK
                     DIYVGVEINKKEIIAPVTPKYISENISNINKTTVKGYVLSWDLLSAPKENIDEIIKWF
                     RN"
     gene            19228..20724
                     /locus_tag="PC466_001467"
     CDS             19228..20724
                     /locus_tag="PC466_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HDF2768857.1"
                     /translation="MSKILEMQQIYKSFGKVDVLKGINFELEKGEVRALLGANGAGKS
                     TLIKILGGVHSQTKGKVILTGNEIMFKNSHHSKENGISIIYQELSLIPTLTVLENIFL
                     GREILKGSVFLNKKDMLEEYMKICEDFDFNIDPHTVVSNLSVANQQMVEIMKAVSCNS
                     EIIIMDEPTTSLTNNEKDGLFKIISRLKSKGKTIVYISHILEEVFKVCDSASIMKNGI
                     MIGTYDVEDLTKLKITQLMTGNDNHKLIEKKDYTFAKYEEPPVLEVKNISWSNKIKNV
                     SFKVYRGEVVGLAGLVGSRRTEIINLIFGIDNKDSGDIFINGKKVDITSPKVAIKNKI
                     GLIPEDRKNLGLILEQAIYTNSSSVQIDKFKKFLFIDRNKEIEFSKKGVKELGIKVSD
                     VKQEVKELSGGNQQKVVVSKWLEKDLDLIIYDEPTKGIDIAAKEDIFNTIKEFSSEGI
                     GVIFISSDLEEVIRVSDRILVTREGSIVDDLKNENIQVQDIMNSIFNV"
     gene            20747..21697
                     /locus_tag="PC466_001468"
     CDS             20747..21697
                     /locus_tag="PC466_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2768858.1"
                     /translation="MKKAFEKLNLRDYGVLLGFLALCIAISIATPSFLGKQNILNLLR
                     QSSIIGIISAGMTFVIISGNFDISVGAVAALAGAITMKFATGGTNLFASMLLGVAICA
                     VIGLINGIVVAKINVPSLIATMAMVTIVRGLLLMLTGGYPITENIPILDYIGNGYLFN
                     IPIPVVIFFIVVLVSFIVLNKTKFGRYVYSVGGNQEASKLNGINVDSHKVKVFIINAV
                     LAGIAGIVLTGRLGTATAIAGEGYDMDAIASVVIGGTSVAGGSGSVLKTVIGVLLMSV
                     INNSFNLLGIDVYFQYIFKGLIILAAVGFDSYSKKKLASR"
     gene            21718..22680
                     /locus_tag="PC466_001469"
     CDS             21718..22680
                     /locus_tag="PC466_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HDF2768859.1"
                     /translation="MKKLMKHLALLLSLVMIFGLVGCSNGGDKEKNGEKKIAVLLPGS
                     TGYFVATKQGIDAKSKELGVSVEYADAQWDASKQLSQAEDFMAKGVDMIALCGVDSAV
                     SERIVKAANDSDVPIVAFTNSIGSNPTGEFKGLVTYIGQNEEETGALTGKIAKNLLGE
                     TGGKAVLIEGVPGTTPQVLRKKGLEKELKDSNIEIVYNQTSNWEKEQALKVTEDLIQK
                     KTDFNVIICQDDNSATGAGQALKDAGLKDKVKVIGLGGSKDGLKAITDGLIDGTTYMS
                     AVEEGGLVIEKASKFLKGEKIEPVTQIKQVEVNKDNISEFKGEW"
     gene            23052..23684
                     /locus_tag="PC466_001470"
     CDS             23052..23684
                     /locus_tag="PC466_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HDF2768860.1"
                     /translation="MARRLFLERIGLIFLGSAILAFGVYNFYYLNNITEGGVLGILLL
                     LKNLFNIQPAIANVVIDGLLLLVGYKFFGKKFLIYSIVASITFSVLYDLFEAIGPLVP
                     QSQNMLLSTILAGVTVGTGVGIVVKAGCASGGDDALALVISKTTSLNIGQVYLATDVI
                     VLLLSLFYLSAFDIFYSLIAVTISGKVIDFIYYHGKSLDMDISNDIVPEC"
     gene            24095..24187
                     /gene="kdpF"
                     /locus_tag="PC466_001471"
     CDS             24095..24187
                     /gene="kdpF"
                     /locus_tag="PC466_001471"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: protein motif:HMM:TIGR02115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="K(+)-transporting ATPase subunit F"
                     /protein_id="HDF2768861.1"
                     /translation="MEGLPMWFLAVVIIMLIIYLVYALINPEKF"
     gene            24228..25910
                     /gene="kdpA"
                     /locus_tag="PC466_001472"
     CDS             24228..25910
                     /gene="kdpA"
                     /locus_tag="PC466_001472"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015391009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit KdpA"
                     /protein_id="HDF2768862.1"
                     /translation="MFMVQIVIVLAIFMILVIPMGKYLYHIATNQKTFGDRLFDKVDN
                     FIYKVCSIDKKKEMNWKQYALALLFTNAVMVFIGYIILRTQSMHIFNPSGIKSMEQGL
                     SFNTIISFMTNTNLQHYSGESGLSYFSQMTVIIYMMFTSAATGYAAAMAFVRGLVGKK
                     KTLGNFYVDLIRITTRVLLPGALIIGLILVTQGVPQTFAGTETVTTIEGKLQDIARGP
                     VAALESIKHLGTNGGGFFGSNSSHPFENPTIISNIVEILSMMILPGACVVAFGHMIKN
                     KKQGWVVFGAMSIIFLIGLVVCFKAESAGNPILSQLGLNQSMGSMEGKEVRFGIAQSS
                     LFTTVTTSFTTGTVNNMHDTLTPLGGLVPLLNMMLNVVFGGKGVGLMNMLMYAIIAVF
                     LCGLMVGRTPEFLTKKIEGKEMKLIALLIILHPLLILMFSGLSVAIPAGLEGISNPGF
                     HGLSQVLYEFASSAANNGSGFEGLGDNTMFWNITTGIVMFFGRYVSIIVLLAISSLLA
                     SKKAVNESIGTLRTDNFTFTIVLVLVVLIVGALTFFPALALGPISEHLVLWH"
     gene            25935..27992
                     /gene="kdpB"
                     /locus_tag="PC466_001473"
     CDS             25935..27992
                     /gene="kdpB"
                     /locus_tag="PC466_001473"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010966942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit KdpB"
                     /protein_id="HDF2768863.1"
                     /translation="METKKTKFITKDIFKTSIIEAFKKLNPKYMMKNPVMFVVEIGFI
                     VTLILTIVPSLFGDEGNNLRAYNGIVTIILFITVLFANFAEAVAEGRGKAQADTLKKT
                     RKDTVARVIDTLGNEKMISASELKLGDIVLVNVGEVIPNDGEVIEGIASVDESAITGE
                     SAPVMRESGGDFASVTGGTTVVSDWLKIRITTKPGESFLDKMIALVEGASRQKTPNEI
                     ALNTLLVGLTLIFMVVLISLYPMANYAGVKIPISTMIALLVCLIPTTIGGLLSAIGIA
                     GMDRVTRFNVIAMSGKAVEACGDVDTMILDKTGTITYGNRLASEFIAVGNADSKDLIN
                     YSVMCSLKDDTPEGKSIVDLGMKLGSTGKTKEAEEAEFVEFSAQTRMSGINLADGRAI
                     RKGAYDSIIKRVKESGGTVPEDLEENVNRVAKLGGTPLVVCVDNEIYGIIYLKDTVKS
                     GLVERFARLREIGIKTIMCTGDNPLTAATIAREAGVDGFIAECKPEDKIDAIKKEQLE
                     GKIVAMTGDGTNDAPALAQADVGLAMNSGTTSAKEAANMVDLDSDPTKILEVVEIGKQ
                     LLITRGALTTFSIANDVAKYFAIIPAIFTLAIPQMEILNVMKLSTSFSAILSALIFNA
                     IIIPCLIPLAMKGVKYRPMKSQAMLMRNMLIFGLGGVIVPFLGIKLIDLLITPLVMIL
                     NLG"
     gene            28011..28637
                     /locus_tag="PC466_001474"
     CDS             28011..28637
                     /locus_tag="PC466_001474"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="K(+)-transporting ATPase subunit C"
                     /protein_id="HDF2768864.1"
                     /translation="MKTLKPALLVSIVLLVVCGLVYPLVLTGVSQVAFKDKANGSMIE
                     VNGVKVGSELIGQSFTDARFFKGRVSSVNYNTYTKEDLVPDKDGNASYGGVSSGSFNY
                     GATNPELHDRVQKDIEKFLKDNPTVKREDIPTDLLTASGSGLDPNISPASAKIQIPAI
                     AKASGISESKLQKIVDDNTSKKLFGVLGEDRVNVLKVNIEVAKILGLI"
     gene            28874..29782
                     /gene="cysK"
                     /locus_tag="PC466_001475"
     CDS             28874..29782
                     /gene="cysK"
                     /locus_tag="PC466_001475"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HDF2768865.1"
                     /translation="MLYNNALELIGNTPVVRLNNLGCTNGCSNIYVKLEKVNPAGSIK
                     DRAVYEMLEGLEQRGELKKGDVLVEATSGNTGIALSMIGKLKGYEVVIVMPETMSVER
                     RDLMKAYGANLVLTDGKAGMAGSIEKANELLKENPNYKSLKQFENKDNPNAHYKTTAV
                     EIMNDVKDLDIFVCGVGTGGTLIGTARYLKEQNPNIRVIALEPKKSPAISENKTGPHK
                     IQGIGANFVPENYDSSVVDEVILVDDEDAFDTVKLLAAKEGILVGISSGANIFGAIEM
                     AKKYPDKKIVTVAPDGVDKYMSMGIF"
     gene            29809..30399
                     /gene="cysE"
                     /locus_tag="PC466_001476"
     CDS             29809..30399
                     /gene="cysE"
                     /locus_tag="PC466_001476"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HDF2768866.1"
                     /translation="MFKKINKDIEYIMKNDPAARSKIEVFLLYPSVHAMIMHRMAHAL
                     YKKKKLFTARLISQISRFMTGIEIHPGAKMGEGILIDHGMGVVIGETAEVGNRVTIYQ
                     GATLGATGKDTGKRHPTVGDDVLIGAGTKILGPLNIGSNSKIGANSVVVKDVPNGATV
                     VGIPAKIVKIRNLEPVKKNKKEVSYEYDELDNVYYI"
     gene            30559..30747
                     /locus_tag="PC466_001477"
     CDS             30559..30747
                     /locus_tag="PC466_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HDF2768867.1"
                     /translation="MKANVNQDTCIGCGLCPSICPEVFDMKDDGKSHVIVDEVPSDAE
                     ESAAEARESCPVDAIDVH"
     gene            complement(30801..31670)
                     /locus_tag="PC466_001478"
     CDS             complement(30801..31670)
                     /locus_tag="PC466_001478"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HDF2768868.1"
                     /translation="MKLNRNDSCWCGSTKKYKKCHMDMDNKIDSFAKLGHIVPTHDII
                     KNESQIEEIKKSAVINTKILDYISDKIEIGMSTEDMNKLVHDFTLQNGAIPAPLDYNG
                     FPKSVCTSVNNEVCHGIPSKDIILKDGDIINVDVSTIFNGYYSDASRMFMIGNVNENA
                     KKLVQVTKECVQKGLEVAKPWGFLGDIGDAINSYAKKNGYSVVREIGGHGVGLSFHED
                     PFVSYVSKKGTEMLLVPGMIFTIEPMVNEGTHEIFVDEENNWTIYTKDGKLSAQWECM
                     VLVTETGVEILTE"
     gene            complement(31867..33111)
                     /locus_tag="PC466_001479"
     CDS             complement(31867..33111)
                     /locus_tag="PC466_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768869.1"
                     /translation="MENNLNIAKKNNTELLQNDSLKVNLQIGVDFTLLSKSLKAFYKK
                     EKDFYCIALAPCNVSSEKANRKISIYDMIKEINILIESITDKNELLSEELFTNNLSEF
                     YDESLDEIYIDLKQAYLYIKKNTDSLNIEDSIEYVFDVDISNDIKAKENPLINFNSLS
                     LVVWSGETKHILQQMNILDLEDIHSYYMENNTNITIYENNTLQYKFDEESEDIKDSSI
                     DIIEQMLILPDDLNYDKDEVENMKSRLAKINIKYLQTLKEKDIKIKLINSNLTDEPEF
                     SDLKYQLPPCWVRSGKTWKDVPGIYRNNSIVAKIGYSNPSYANVHSSKNLELHETAHA
                     IDKNVLNKKSNSEEFMEVFAQERYKLYDPKQVAHAYISKFIEEFFAESFVHYYLDEDS
                     KNTLKENCPLTYDFLEKLELNY"
     gene            33402..33713
                     /locus_tag="PC466_001480"
     CDS             33402..33713
                     /locus_tag="PC466_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HDF2768870.1"
                     /translation="MYFTYIIRCKDDSLYTGYTSNIVRRMNEHKLGINSKYTRAKGFE
                     KLEVYFVTNTKSNAMKLEYYIKKLTRNKKLSIIKNPSILINLIDNKEDYIIGKEIEQL
                     T"
     regulatory      33806..33898
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            33998..34792
                     /gene="thiD"
                     /locus_tag="PC466_001481"
     CDS             33998..34792
                     /gene="thiD"
                     /locus_tag="PC466_001481"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HDF2768871.1"
                     /translation="MSNYKIPTLTIAGSDSSGGAGIQADLKTFSAIGTYGMSVITAIT
                     AQNTKGVFAVEDLNKKIIKKQIEAVFEDIPPRAVKIGMVSSPEIILEIVENLKKYNPK
                     YLVVDPVMISKSGYYLLKPEAKENLIKYLIPLAYIITPNIPEAEEITGIKIHNVDDMK
                     RVGEEILQLGPKFVLMKGGHLDGEAVDILVGKNIFKVYKSERIDKKNTHGTGCTLSSA
                     ITSYLALGYEITEAVNLSKIYITEAIKRSFDIGHGVGPVHHFYKFE"
     gene            34816..35604
                     /gene="thiM"
                     /locus_tag="PC466_001482"
     CDS             34816..35604
                     /gene="thiM"
                     /locus_tag="PC466_001482"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HDF2768872.1"
                     /translation="MYNLIKDVKKLNPLVIHYTNNVTINDCANVTLAVGASPLMSFSY
                     EEVEEMVSVANSVVINIGTMNSNMLDLFLLAGKAANKYNKPVVLDPVGVFASKARAEL
                     TSRLLNEVKFSVVKGNVSEIKFIGGFNVRGKGVDSFDEEEDSTEIIRKIAEKLECVVV
                     ATGKIDIITNGKGIYKINNGTDKLKGITGTGCMTASLIASFMAVTENILEAATMGVLT
                     MSLSGELANLNNPPIGTFKENLMNAIYQMDIDTLSKNSNIEFLN"
     gene            35627..36259
                     /gene="thiE"
                     /locus_tag="PC466_001483"
     CDS             35627..36259
                     /gene="thiE"
                     /locus_tag="PC466_001483"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HDF2768873.1"
                     /translation="MIDKESLKKCLKLYLVTDSEMLKGRDFYKCLEDAISSGITTVQL
                     REKNASGREFLRKAMKLREITERYGVKFIINDRVDIALICDADGVHVGQSDIDVREVR
                     KLIGNNKILGVSARTLEEATCAKNDGADYLGVGSIFTTSTKLDAKSASFETVKEIKEK
                     VDMPFVLIGGINLDNIDKLKCLESDGYAIISAILKAEDISKEVEKWTLKI"
     gene            36398..36700
                     /locus_tag="PC466_001484"
     CDS             36398..36700
                     /locus_tag="PC466_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2768874.1"
                     /translation="MIKILLVCVGGMSSTLLVNKMEKDAKKRNIDCKIWAVGEGDIKS
                     ELDNFDILLLGPQLRFMLDDVKSIVGDRVPVSIIDMVNYGTCNGHAVLNSVLEILK"
     gene            complement(36766..37515)
                     /locus_tag="PC466_001485"
     CDS             complement(36766..37515)
                     /locus_tag="PC466_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2768875.1"
                     /translation="MLNILWRSMKWRFKNPISFVVTILQPFLWLVLYSSIANQTMNNI
                     NINNYTAFILPGIIVLVVFSSCSSGGIINFIMKNSGSFYRVLIAPISRYSIVLGQLLE
                     AILVSFIEVTILCIVSIFFSVRIESGIGGILLMIVLIFMTAFFLSSLAYSISLLLPNE
                     IVYETIMTAIVLPIFFLSSALFPIESLSGGLKVAVMLNPFTHVINALRSLIFGETILI
                     GDILPVILLFLILCCSSFSLAMWRLKKEMVS"
     gene            complement(37509..38471)
                     /locus_tag="PC466_001486"
     CDS             complement(37509..38471)
                     /locus_tag="PC466_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2768876.1"
                     /translation="MLAIEIDNLVKEYKNGVKALNGLSFNVNAGEIFSLLGPNGAGKS
                     SLINILTTFYKPTSGNVKMFGKDLVDNPSWIRTQIACVAQQISIDEHLSLMENMVFQS
                     KMYKVEPQIAKQRIDSLIDKFDLSSYLKYPTSSYSGGVKRRLDIAMNMVSSPKILFLD
                     EPTVGMDVDSRKSMWDMLLKIRDEYGTTIFLTTHYLEEAEQLSDNICIMKNGKDLAQG
                     TPSSLRSYIRQNILRITFHNTEDIKKYKDSIKSTGLVKFMSVRENSIFISVNDSRTAF
                     TLINKWLLEHDIEFDAIEIVEPSLEDVFLALTSSKKSLKEEWEC"
     gene            complement(38475..38933)
                     /locus_tag="PC466_001487"
     CDS             complement(38475..38933)
                     /locus_tag="PC466_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HDF2768877.1"
                     /translation="MNCKIEIKNIESVTVATMRYNGPMTEATKYFPNVFKAIKGKSNG
                     APFFCYYDVDQKTGVAEMELCVPTAETPNRMGITTKEFPKTKALFFTHTGSYSNLPKT
                     YEMIFKYIHENNIKIQTPWREVFIKGPGMLIKGNPDNYITEIIFPLKEEE"
     gene            39289..39645
                     /locus_tag="PC466_001488"
     CDS             39289..39645
                     /locus_tag="PC466_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2768878.1"
                     /translation="MNFELDNTTPIYLQIVKYIKRQIVTGELKPGETIPSRREMALNL
                     KVNLNTVQRAYKEMGDMNIINTFKNYQSSVTVDENILKNLKLELINESLSVFIEDMKA
                     INVSKEEVLKIIEDKY"
     gene            39717..40433
                     /locus_tag="PC466_001489"
     CDS             39717..40433
                     /locus_tag="PC466_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2768879.1"
                     /translation="MIEIKNVSKTYKRMQGLKIRKIEALKNVSFNIEKGKITALLGIN
                     GVGKSTMLKAIAGLINIDSGEIRIDGEKINEKVYNKLAFVPDVQSHFSNTTIKETFEF
                     MEIFYSKWNKEKSKEMMDIFKLDEDEIIDNLSKGNIARVKLILGFCQDPEYILLDEPF
                     TGIDLFKREEFIGVIAQYMEENQAIIITTHEIVEIESLVDEVVILDEGQIITSFNAEE
                     LREREGKSILDKMREVYKNE"
     gene            40426..41250
                     /locus_tag="PC466_001490"
     CDS             40426..41250
                     /locus_tag="PC466_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2768880.1"
                     /translation="MNKLLYLINVDLRRSNKFYIAYISFFSLITLSLNLFEINKFKNS
                     KFIMNLAIEDFGGIFYGLGILSNLGFIQNILFFGMLGLFIYYIFMWKREFFSNNQSIY
                     TLMMLPQNKFKICISKSIVLITMIYGFLISQTATLFICKYIFNFIFRNIPIINMNFAK
                     DLYYLNLKSIPIDFISFMAIYVFLLLIAISIVNCCILFIFSYINKFYVILITLLIIAG
                     LYFSTIYINIINLFRKYYNLIGFQFNNLVAGLLSFLIIMFILNGISYLLIKKKVSL"
     gene            41262..42461
                     /locus_tag="PC466_001491"
     CDS             41262..42461
                     /locus_tag="PC466_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768881.1"
                     /translation="MKLKSKISILIIFLTLAIYFSIGLLNNEDNLKIKTIKGDSNELD
                     HININFGYALNGYINSYYTINGSNKTKKTELIKLQKDSKNTNNLIDVSSGSDLIAHVG
                     FEMNEESKDINFVIDEKKEDLEKGVFPSEGSDKEIEYEKLDMNNFTRTRYKVDKSTDD
                     YYANILASKRYKKYLYVSVLYATSDSSENNKEYSSTIDIIKINPENKKIKTIKSINLS
                     NYFSEKYQDIENIGVSYASKYEDKMYILVNVLNTNIGDNSNSKFHLLEYNLEENKESI
                     MELKTDSKMALAKAKLEANKLYMVMSNDYDNSSITELNLLTYNILDKSLDEDKYVLDN
                     REKRGIRSIEIDSNKIVAYTSRLNSILSWDNKFMLYIINKNSKEIVYEGELQFNSSNS
                     MLEFEIK"
     gene            42470..43282
                     /locus_tag="PC466_001492"
     CDS             42470..43282
                     /locus_tag="PC466_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768882.1"
                     /translation="MKDLIRLFEFELKRNIKNYIFIIICCCSFVILNIVKNLNDYNYI
                     IENAVKSEQLTKIGNTIETVNVTGFSSFRNIMGSTESWFIFGIIACICYAFFIWYRDF
                     NGRSKSIYTLIMLPKNRINIYISKLLNILFLVYSYTVVLTISLFIASKLLPRHMLGNV
                     TNYGFVQETIYELKMLLPYSFEILFVEYIFLLIGFVSVVFTSILINKSIYKVSTLISF
                     LFLVLEILVFIISIEFIIPYEYSDVFTVLYSSINIFVCSLISNKLLKQKIDF"
     gene            43293..44561
                     /locus_tag="PC466_001493"
     CDS             43293..44561
                     /locus_tag="PC466_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768883.1"
                     /translation="MKAKNIGKYTICFIIVCFLMITMTLILSYFNKDKLSVKTLKGNV
                     KDIGRVSVVYTPNISKFSYEEVIISKNGVRNNKNPKSRIRNDYLNIDKKYSDFVNDKG
                     KELIYKDDLNIGEAYTSVKSDLVQGMNALNDCIKVSNKNLKSGVEENFDINLNKSDFK
                     ENSWKTLFNKIYKGNLYMVISETNISGSKVNNICILKIDIKNKSYKLLNRFNLGLQNG
                     YQQNINEIKFSIGSKLYLEIVNNKSKNGDIEGHDSYSNLIIYDIEDNTFNISNKFMDN
                     LNKEKNANPKEIGLLSKTKLDYMIKNNKLNLIVTDMSNSIINLVYDINSNEIKLEDYE
                     ILDLKVDYNEASSGVRKVKLLDDKIYSISGMKNSISGELKGFKGIVDVVGTKPVKFQV
                     FDMKLKKNIYEAELINGDISLQEKLFFVAN"
     gene            44927..46108
                     /locus_tag="PC466_001494"
     CDS             44927..46108
                     /locus_tag="PC466_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HDF2768884.1"
                     /translation="MNKKYIKAGNLIDGTGNSIMQNKGIIIDGDTIVEIEDIRDDLNG
                     YDVYDYLDKTVMPGIMNCHVHLTMEPVGNPKIYYDNVSDVELVVNTIKQVDAYLDSGV
                     TYIRSLGCPKYVDVQLKNLIDKGSIDGPGIVTSGPVICMTGGHGYYFGIESDGVDECR
                     KSARTVLKNGVDCVKIMATGGVTTDGVEPGSPQLTLEEMKAAVDEAIKAGKITATHAQ
                     GRTGIKNAVLAGITSIEHGVYLDDEIIDLMLERGTYLVPTVAAPYFILNAGKESGITE
                     ATLRKCEIVAIPHKESFLKAYKKGIKIAVGSDAGTSYNEHGKTYYEMKLMSDYGMDNM
                     DIIVAATKTASELLRIDKNYGTLEKGKKADVIVVNGNPVENIDVLADVLAVFKLGKKV
                     R"
     gene            complement(46250..47167)
                     /locus_tag="PC466_001495"
     CDS             complement(46250..47167)
                     /locus_tag="PC466_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768885.1"
                     /translation="MENNKCREDFRFTQEYEEDYPNTNERYYENYQVADRYYNYPNKY
                     KEPKIKQCCCKKSMREALELLRYDALRPFVNFNQFAFISDFFIVGANLVGIDLSAPPK
                     DNLSGLDGTFERFSACNCDLIDIAGRVSYPIPVPLTLEGLINTIGTIPGVAELIALID
                     AVIPPTIDLGAILDAILAAIIDFILAASTPLANVDLASLCNLKAVAFDITPADYEDFI
                     ASLGYYLDKKHYKECNCNCDCDDCCCNKGILDNLYMSNINNQVTVVAGSLVLTGVEVL
                     GKKNDVIVLGNSNDSRIYFVCVDSIDYIA"
BASE COUNT        18448 a         4957 c         8097 g        15707 t
ORIGIN      
        1 tgaagcagga accctgtgac tttagtcatg ggaggttcag atttggtggc aaaataataa
       61 gaagaaatga aaagactaag tttgactggt taagtagaga taaagaacaa gttgaaaaat
      121 atataaatga cccattttgt ggagtagtgt gtagttgtgg ctttttttat gatttagttc
      181 aagggttaaa agaaattgag gataaagaaa acttaaaaaa agtgccactt gatataccta
      241 tttacataat atctggagat aaagacccca taggaaaaaa tggtaaagga gtcttaagac
      301 taagggatag atatataaaa ttaggagtaa aagatgtaac ttgcaaactt tacaaagatg
      361 gaaggcatga attgttgaat gaaataaata gagaagaagt ttttgaggat ataatttgtt
      421 ggttaaacaa taaaatagaa atattgtaat aaaaaaatat aatgatatat ttgctttaaa
      481 tttatttata tataatattt gaaaagtgga ttatgtatat gcaaagtaga aaagagagag
      541 cctagaagtg attttttgct ataatgccat ttattgaata ggtgggtgtt attataaata
      601 aattattaac actcagtatt attatcattg tatatggaat ttattttatt taaaattcct
      661 tgaaagttta aatatagtaa gttgtagtaa agagaaaatc taaatattta aatgctattt
      721 aatgtgaatc tattaattag gttatactta aacttaatta atagatttta tatttcaagc
      781 caatgagata gggttttaga ttaaaatata accaatggtt aaattacaga cattttgtta
      841 actttccctc gatttactag taaatatttt ttttatatac ttaaattaca acagatgtac
      901 tagggaggta tatatgcaaa ttaaaatagg taaagtcata cagcgtctta gaaaagaacg
      961 aaatttaact caagaacaat tagcaaagtt tataggtgtg tcaacaccag cagtatctaa
     1021 gtgggagagt ggaaattctt acccagatat agaattattg cctttattag cagacttttt
     1081 taatgtgtct attgataagc ttttaaatta caagattgat ttaagtgaag aaaaagtaat
     1141 gaaaatttat aaagaattag aatcaggctt tgctagaatt gaaattgatt tatcaacaga
     1201 agaaccaaaa gaagaattta gacaagactt agaatctgta aaaaagcttt ctaatatgta
     1261 tatagagaag tatcctaaaa gctatttatt gaagctaagg atatgttcgc tgtatcagat
     1321 gtattcatat aaatttggta agagtgaact taatgacaga gtaaaagaaa caacgaatat
     1381 tcttgaagat atagtgagaa atacagatga tatccaaata aaagaaacag ctcttattat
     1441 attatcaaac gcatattgta tgttggaaga ttatgaaaag gcagagttgt atttaaatat
     1501 gatacataag tcaatagggg atacaagtgt taatttagct atgatatatt taaagcaaaa
     1561 tagacttgaa gaagcagaaa tattgcttca aaataaattg tttagtaata tatttaatat
     1621 aagcatggat tgtaagggaa taattaatgt atacaaaaat caatacaagg aattaaagaa
     1681 aaaattggag aatagaaatt ttaataaaaa tgcaattgag agagaaatgg agtatataaa
     1741 aaataagttg ctgtggtatg caaatctttc tttagaaata aaaaaaatgc tcagtgaaga
     1801 taaaggtgca ttttttagta tgtatgtgga ttatatggaa ttatctctaa tttttttatt
     1861 ttttaacatg aaagaagaag caaaaaaagc cttatatagt ctaaaagaaa tattagaaaa
     1921 atatcctata catgaaagtt tggatgtaag tcaaatgaga ttttttgata aggtagagtc
     1981 taaaaattta tatactttta atatatatac aaacttgtta attgtactta atgatgacag
     2041 ttataatgag cttagagaag aaccaatttt taaggatgta attgaaaaga ttttagatat
     2101 ggaaaaaatg ttgaaaaata aagaataagt aaaaatttaa tataggactt aaagattaat
     2161 caaattaaaa gaaagtgttt caaaataaaa atttgaatca ccttttttgt tggtcttaaa
     2221 ccgttattta gaaaaataga ggtttcaaaa tagaaatctg aattatctgt attattacac
     2281 aaaaatagaa acctaaattt ataaaaatag aataaagttt gttatataaa atgtaatttt
     2341 gtctataaaa tctcacatgt tttcttaact ttaagcgtga aaaagaggat gtatcatgaa
     2401 ttttttagtt catgatgcat ccttatttgt atgaaatcca atatatcttt attatttaaa
     2461 caatggaaaa gagtcttatt tctattttga gacatctctt ttatttaatt atgaagtttt
     2521 atacagttca ataaatagga attatattta gaaactcatg acattatttc ttagatagtg
     2581 attaaattta tcatattcca ttttagataa cttttctggg taagacatta caatcaggtt
     2641 atgcccattg aatttttcat ggtatggtgg atgaatgtgt tcataattat ttgtcttata
     2701 ttttactctt tcatagaacg ccttgcgata aattgaaatc tcatcaattg gaaggtcaat
     2761 ttctaaaata atagtttttc ctttcttatt taaaagctct aacgctcttt gtccatatct
     2821 attattgcgc atttctggaa aaatgcagaa atgttctaca tagataaagt tatctgtttc
     2881 ccaacataaa attatgccga caaactggtt tttatcataa attaaattga attgatattc
     2941 tttatttttc aaaatttctg tttgcaaata agattttctt tgttcatgaa atgggaaact
     3001 aattttatat aattccatag ccttgtaata taatttattt tcactggttc ttaaccgttc
     3061 aaatttcact ttactcctcc taatcacgaa aattccaatt tatttatgag ttcattttac
     3121 catagtcagt atttgcatac aatgtgtttt aagttgagtg tcatttcttt cttttattta
     3181 tgcttatatc tcatagacta agagataatt gcttaagaca taactaaaaa ctattatatt
     3241 aagctttgat aatctaaaaa cagtatattt atggactttt ctaggtctaa aagtaatctt
     3301 aataatttta gaagttacaa aaaagttaca taaatttgga aagctataat atacatatat
     3361 aatataaggt taaaactgta atgaataata ttaatttaaa atttgaacat ggaaggagat
     3421 tattatggag aaaagagaaa agaggataat aatatcatct ttattaagtg tatcaatttt
     3481 aatgggtttg gtaagtatat attctatatt aaataaagaa gacataattt taactgttaa
     3541 gggtcaagag caaaaagtat cttcctttaa gaaaacagtt gaggaacttt tggatgaaca
     3601 gggtgtaaag tataattctg aagataagat taatccaagt ttagatacag aactaaaaga
     3661 tgatatgaaa ataaaagttg ttaaggtaac taaaagtaaa aaagaagaga ttgaaaaaat
     3721 tccatttgat acaaagcatg taaatgatag taatttgtta aaaggaaaat ctaaagttta
     3781 tcaagaaggt caagaaggag aaaaaaaact agtctataat ttaacttacc atgatggaaa
     3841 attagtcaaa aaagtcttat caaaagaagt aatatctaag gagccaacta caaaaattat
     3901 aaaatatgga actaaagaaa aagtactaat agcatcaaga ggagcaaata taagaggagg
     3961 caaacatatg aaagtggttg ccactgcata tgcaggagat acaataacat ctactggtac
     4021 aactccaaga tggggtgtta ttgcagttga cccacgtgta ataccatatg gaacaaaagt
     4081 atatatacct aaactgggta tgacttttgt agcagaagat tgtggaggtg caattaaagg
     4141 taatagaata gacattttta tgaacagtga aggaaaagct tcaaattggg gaaggaaaag
     4201 tatagatata tatctacatt aaattagtga atagaataac tttacttgaa ggacaaaaaa
     4261 gtataaaata tgaattaact aaactgttag attattctta aaacataaaa atatatctaa
     4321 ggggggataa gatgaaaata gtctgcttag gagacagttt aacgtatgga tttggagtat
     4381 cacgaagtaa ttcatggaca aacattgtaa atgaagagac tcgattagaa atagtaaata
     4441 agggtataaa tggtgataca acaagtggta tgttagctag gtttaatgaa gatgttgtaa
     4501 aaaactctcc tgatatagtt tttataatgg gtggcactaa tgattttatt gctggtgcgg
     4561 gaaatgaaat tattaattct aatataatgg ctatggtgca tcagtcatat tcaaaaaata
     4621 ttatacctat aataggtata ccattaaaac cagatattcc aaatgttagg gaagattgga
     4681 gttgttttac tgattttaat atagtatctc aaaacttaga atcatatagt tattggataa
     4741 aaaaattttg tatgacattt aatactaatt tcgcagattt ttattcagaa tataataaaa
     4801 atatggaact agaaggatat aaaaaattat attttgatgg gttacatcca accaaagagg
     4861 gtcatagaat aatggcagac atttttatta attcaattaa taagtatata gaagagttat
     4921 agattacatt aaaatgcttg tttatgcgtc agttgcaata aatacataca gtagagaggg
     4981 gtttattatg gattatacta aaacttatga agagtggata aagggttcat attttgatga
     5041 agatacaaag ctagagttgg agaatataaa aaataatgaa aaagaaatag aggatagatt
     5101 ctataaggat ttagaatttg ggactgcggg tcttagagga ataattgaag caggaacgaa
     5161 tagaataaat aagtacacag ttagaagagc tacttttgga ttggcaaact atatattaga
     5221 aaacacaaca aaagaagaaa caagtagagg agtagtaata gctcatgata atagacacaa
     5281 gtctagacaa ttctgtatag aatctgcaaa tactttggca gcatgtggta taaaagcata
     5341 tatatttgat agtttgagaa ctactccaga attatctttt gctgttagaa gcttaaatgc
     5401 aatcgctggt atagtcataa cagcaagcca taatcctcca gaatataatg gatataaggt
     5461 atactgggaa gatggagcac aagttatgcc agagattgca aatgcaataa cagagaaagt
     5521 aaatagtata catgattata gtacaatacc aaccttaacg gaagctaata aaaatttggt
     5581 agttttgttg gacgaatcac aagatactaa atttatagaa gcagtaaaaa gccaaattat
     5641 aagaaaagat ttagttaaaa atgtaggtaa aagctttaag atagtttata cacctctttg
     5701 tggaacaggg aatgttccaa taagaagagc attgaaagaa gttggttttg aaaatataat
     5761 tgtagttcca gaagaagaaa atccagaccc aaattttgca gggcttgatt atccaaatcc
     5821 agaagagaaa aaagctttaa atagaggtat attactcgca aaagaaaaag gagcagacct
     5881 tgtaatagca actgacccag attgtgatag agtaggtgta gcagtaaaaa ctactacagg
     5941 tgagtatgct ttacttacag gaaatcaaat tggtggtatg ctgacacatt atataataga
     6001 aggattaaaa gaaaataaca aattaaaaga aaatcctaca ataataaaaa ccatagttac
     6061 atcagaattt ggagcagata tagctaaagc aaataatgtt gatgtattaa atgttcttac
     6121 aggttttaaa tttattggtg aaaaaataaa attatttgaa caaaataaaa atagaagtta
     6181 tgtatttgga tatgaagaaa gttatggtta cttagttggg actcatgcta gagataaaga
     6241 tggtgtagtt tcttcattgt taatatctga aatggcagca ttttactatt caaaaggtat
     6301 aagtttatat gatggtttaa tagaacttta taaaaagtat ggatttttca aagaacagac
     6361 tatatctttg actttaaaag gtatagaagg tgtagaaaag ataaaagaaa taatatctta
     6421 ttttagagaa aatcaaattg attatataaa tagtattaaa gtagttgata aaaaagatta
     6481 taaaaatggt atagataatc ttcctaaatc taatgtttta aaatactttt tggaagatga
     6541 atcttgggta gctataagac catctggaac agaaccaaaa cttaaatttt acatagctgt
     6601 aaaaggagct agtgatattg aagcagataa aaagattcaa ggtttgaaaa agtatataga
     6661 tgacatggtc gaaaaattaa aataaaatat tattatttta taagataatt ttgtaataat
     6721 atttatttag ctgaaaatta taatttactt tcattgagta gaatatggaa atgttagtag
     6781 aattgttatt ttcagctttt atttgtgtta tttttactta aataattata ttatagaatg
     6841 aatctgagta taattaatat tgtataatga aattaatttg atagaaaagg ggatatttat
     6901 gtttggtata gataagaaat tgattgaata tataattgca aaatccaatt acagtgaatt
     6961 aagttcaaag tcagcagaag tatctttctt cttaatgttg tccatatttc cttttttaat
     7021 atttacaata agttctatag cttatatacc gattcttcat ttaaataagt atatagcttt
     7081 gtttagaaat atgatgccag aaggtgcttt tgctgtgtta tcttcaatca tagtttctgc
     7141 aatagacaat agaaacctga aatttttagc agtcagtttt gtacttacta tgtggacatt
     7201 ttcaagagca gtaaaagctc ttattaaagg aatgaataga gcctataaag ttaaagaaac
     7261 taggtctttt tttaaaattt tatctatatc atttttattt acaataatgc ttttggtcct
     7321 tattttttta tctatgatat ttttagttta cggggaaaaa ataggttatt ttatttttaa
     7381 tcttgtagga ttggatgaga tatttataaa aatatgggat attctaagat acactgtagg
     7441 tataataaca ataatagtga tatttacact tttatataaa tacactccaa ataaaaagtt
     7501 aactattaaa gaatctgcgc caggtgctat ttttgctact tttgcttggt ttttagtatc
     7561 atttttatat tcttattata caaattacta tgctaactat gaagtaatct atggaagtat
     7621 agctgaaata attgtactta tgacctggat gtattttagt agttggtcta tcgttattgg
     7681 ctatgaggta aattcaagat tgtattttag aaagataaga catgaaatgt taaagtaaag
     7741 tatttaaaat aaaagagagt atttagtatt ataaatgtaa ttgaattaat aaagaaatat
     7801 tgacatttaa gttaaaaagt ctagaatttt tctgggcttt ttttattttt agtataactt
     7861 gacaaatttt atttaatggg atagttttaa tttataatca tctttgaaaa gatgactatt
     7921 gataagtaag gtataaaatt ggtaagtatc aaaaaatata ctaaataaaa attatagtcc
     7981 taatgagtta atttctgtat tttcaaataa tgcagtattt agtcatgtgt ttttatatgc
     8041 gcctgtattt ccaattacca atatattaga ataagctact gtaattagat ttagaaaaaa
     8101 gcgacataaa taattataaa caaataataa attacataaa attaaattta ttcacaagta
     8161 tatcttataa aatatgttat aattaataga aaattgtcat ataattaatt aagtagtatt
     8221 attataaata acattgaaag gtagtggtta gaatatggat atccataata aatatgtaaa
     8281 ttttataaaa aatatacctg tacctttttt atattgtaga attgtaaaga gacaagaaga
     8341 tatagaatat cgagtagaat atataagtaa gggtatgggc aaagtattac aattagaaga
     8401 aggtatttgt gataaaaata tactagatgt attgcctgta tttaagtcta aaaaatattt
     8461 caaagagttg ttctcaaatg aagtggattg tataaaaagg tacattccga cacttaaaaa
     8521 ctggataaat ataaaaaaac agataatagg ggattcatac ataattttgt attttggtaa
     8581 aattgtattt gattatagac agataatcga ttcctttgat aaaaaggaaa aagtagctta
     8641 tattaaagac gaagaaggca tatatataga ttgcagtgaa aatttaatac caatattaaa
     8701 taacaacatt aaaacaacga aagatatctt tggtaaaaat gatatagaag tatggggaga
     8761 gaatacagga aaattattta gagatgatta tagaggagga gtatctagta aaaaaagatt
     8821 tttacaaaat ctttttgaat atgaagaaac attttttatg gttgaaaaat attttttgta
     8881 tgatgaagac gaacttttag gtactatagg gataatagat aatataatat atagtggtta
     8941 cagtaataga aattataact caaaagattt aatgaagatg atagaacact caattccaga
     9001 gaatatgttt tataaagatg tgtatggaaa ttatattgga tttaattcag gttttttgaa
     9061 tttagcttgt atgaataaag aagaattatt agggaagaat agttataaaa tatcagaaga
     9121 agaagcttta ataaataaga tatttgaaag tgataagggt gtagttgaaa ataaaaaagt
     9181 agttacattt gagttaaatg taagtataaa tgatgaaaat aagtgtattg agattacaaa
     9241 aaggccgttt tttgatagct atggaagtgt tattggaata attggaacag caagggatat
     9301 aagtagaaga aaaagattag aagaggaaat ggataaaact aggatggaat tttttgcaaa
     9361 tttatcccat gaacttagaa cgcctataaa tttaatatca tcttcattac aagtgataga
     9421 aaaaaaagaa gcagatttaa tagaatcaaa tgatacttta aaaagaaatt taggtataat
     9481 aaaacaaaat ggaaatagaa tactgaggtt agtaaataat gttatagact ttacaaaaat
     9541 gcaatcagga tatttagatt ttaaaccaga agaatctgat ataattgcat ttatagagga
     9601 gatatgtatg tctgtagctg attttgcaag ccaaaataat atacaactta catttgatac
     9661 agaaatagaa gaattttcaa tgttatttga ttcagaaaaa ttggaaagaa taatattaaa
     9721 tttactttct aatggaatta agtacaataa gaaagatgga aaaataaata tatttttata
     9781 tgtgaaagat aatgtattta atatgaaaat atctgatagt ggaataggta taccaaaaga
     9841 aaaaatagat aaaatattta atagatttga acagattgac aatgaacttt cctacagagt
     9901 taaaggaagt ggtattggac tttcattagt gaaatctttg gttgaattgc atgagggaag
     9961 tatatcttta aaaagtcaac ttggtattgg aagtgaattt atagtttcat tacctgttag
    10021 aagtgaaaat aatattgaaa aatataatca taaaagagaa atcagcaatg aactaagtaa
    10081 aaaattagaa atagagtttt cggatttata agtttaaata taaaaaataa aattttaaaa
    10141 aagtattgac aattgattta gaagggttta aaataaatta caacataata aataaaaagg
    10201 cgatgaatag gaagagtaaa tctaattcga ttaccagaga gaagagtcca ttggctggaa
    10261 gactttttaa attagaggga ttgaaaacta cctaggagct actttctgaa gtcatctgca
    10321 ttagtagatt ttagtaagaa tagtcgttag ctgcgttaaa gtgtaaagtg agttttcatg
    10381 atatatgaaa actaaattag gtggaaccgc gggaataata ctctcgtcct tatgttataa
    10441 ggatgagagt tttttgttgt ttaaaaatat aaacagtaat cataataatt atagaaaata
    10501 taaaagcgat gaataggaag agtaaattta attcgactat cagagaggaa agttcacagg
    10561 ctgaaagact ttctaagttt gagaaattga aaactaccta ggagctgtgg tctgaagtta
    10621 ctttaaaaag ttttagtaag actaaccgtt aactgcgtta aagtgtaaag tggattttat
    10681 caataaatga taaaatcaaa ttgggtggaa ccgcgagtat agactcgtcc ctttatatag
    10741 ggatgagtct atttttattg caataaaaga ttgaaaataa aaaaaaatcg gaaaattata
    10801 aatttaggag gaaaataaaa tggaaaataa agtgaaaatt ggagtactag gatatggagt
    10861 tgtaggaagt ggacttatag atataataga taataataaa gaaaaaagaa gtatagaaat
    10921 agttggaatt ttagttaata atttggaaaa acataaggat aaaaaatatt ctaatataat
    10981 aactaataat atagatgata tatttaataa agatatagat atacttgttg aagtcatggg
    11041 tggtttagaa ccatcattat cttatataaa aaaagcatta aacaataaaa ttcatgttgt
    11101 tacagcaaat aaagatttgt tagctgaatg tggagatgag cttgcaaaat tagcaagtga
    11161 aaataaagta agtattaaat ttgaagcttc agtcgcagga ggtattccag tattaaaacc
    11221 aataatagaa tcactagaag gaaataatat agatagtata aatgcaattt taaatggaac
    11281 tactaatttt atattatcta aaatgtatga tgagaatcta tcttatgata tggcattaag
    11341 acaagctcaa gaattaggtt ttgctgaagc aaatccagag tcagatgtat tagggtatga
    11401 tgctgctaga aaactatcaa tattatcaac tctagcttat gacaatagag tatattggaa
    11461 ggatgtgtat ttagaaggaa ttacagatat agatgaaaaa gatattgaat atgcaaaaaa
    11521 attaaattgt aaaataaaat tgattggtca aagtaagtat gaaaatgata aagtaagtgc
    11581 ttttgttaga cctgttttag tagaaaaaga taatatcctt gctagaatag acaatgagtt
    11641 caatgctgtc atagtgaatg gagattcagt aggagaagtt tcttttgtag gtaaaggagc
    11701 tggaagttta gcaacaggaa gtgcggttta ttcagatgtt atagatataa tagataatag
    11761 agtttcaagt atagattctt ttactaaaga taaaatacaa gttaataaaa tagttagaga
    11821 aaagtgtgga gcacttctta gatttaaaaa atgtaataaa gatgaaattc taaatatagt
    11881 tgagaattgt ttagtaaaat tcgatatttt aaatgatgat gatgaacttg ctattatggt
    11941 ttatgctgat tctgaatatg aaataaacaa cagtttatgt ctaataaaag ataaaggata
    12001 ttgcgaaaaa atgaataaaa tgttgaaaat aagttaaaaa agaaaaaata agtttatatg
    12061 taacatattt tgacgatttt aatactatat agtatgagat gaaacaaaac atctcataaa
    12121 aaattaaaat tcaagggaga gatatgttat atggaaaata aaaaatatgc aaatggtggt
    12181 tattcagaag actggtatga aagaggagaa tctacagcta aatggttcca gaatgataga
    12241 gaagaatatg aaagagcagc atacgatgaa gatagagaaa gaagaggctc aaactgtgga
    12301 tgttcagatt caggaggaaa tagacctaga aactgtgaaa gatttagaag agaagctgag
    12361 ataagagaaa gagaagcaag agaagcattc tgtgaatctt cagagagaaa gaaagaagca
    12421 ctagcatatg aatgtgaagc tagaaaatta tgggaagaag cagaaaaata ctgggatgaa
    12481 tattcaaaat acaactataa aggaatcgaa tatttagcag aagctgctag attatttgat
    12541 gaaggtatgg aatgtgaagc tagaagaaat ggaaataatg gaggaaacaa taataattgt
    12601 tgccataaat gccataaatg taattgtaac tgctgtagaa aataaaaaaa ttcattgaca
    12661 aatcaatagt taaaatatat catattatgt ataataaaga gaaaattcag aaaaaaataa
    12721 tgattagaat aaatttaagt atatttatta gacaaatagt gctcagttag tgaggtgagt
    12781 acaatatgat taaactccca tcctctagct tttgatagag ggtgggagtt tttatttatt
    12841 gatatatctt aaatgaggat aatattgtaa aataaatgag tatgagattg taaaattagg
    12901 aggtaaaaaa tgaaaagtat taaaacatca agtatgaaag aaaaggtaga tgaaaagata
    12961 ttaagagagc aagtaagttc tataatagaa gatataagaa ataataagga tgttgcactt
    13021 aaaaaatata atgagaagtt tgatagaaat acaagagatg aatttagaat tactaaggaa
    13081 gaaataaagg aagcttataa gcatgtagat gacgaattta taaataactt aaagattgct
    13141 gccaaaaata taagagaatt tgctaaagct caaaaactaa gttttgaaaa cccttttgaa
    13201 aaagaaattt atccaggtgt aatcttaggt caaactaata ttccaataga gtcatgtctt
    13261 gcatatgttc caggaggtca gtatccattg ttttcaacag ctcttatgct tataatacct
    13321 gcaaaagtag caggagtaaa aagaatagtg gcatgttcac caactatgaa aaatactgaa
    13381 aagataaatc ctaaaacatt ggtagctatg gatatagcag gtgctgatga aatatatgca
    13441 actggaggag ttcaagctat agcagcattt acatatggaa cagaaaagat taatccagtt
    13501 gacataattg taggaccagg aaataagttt gtaactgaag ctaaaagaca atgttatgga
    13561 caagtaggaa ttgattttgt cgctgggcca agtgaagttc ttataatagc ggatgaaact
    13621 tcaaatccag tttatattgc agctgattta ttagcacaat gtgagcatga tttaaatgca
    13681 agaggaatat tattgacaaa tagcttggaa gtagcacaaa aagttgaaaa aaatatagaa
    13741 agtatgctaa aagatttgcc aacaaaggac atagcatata gttcatggga aaataatgga
    13801 gagataatat tggttgatga tatggaagaa gccattaaaa taagtaattt ttatgcacca
    13861 gaacatttag aagttgcagt aaatgagtat aatgatattt gtgatagatt aactaactat
    13921 ggttctttat ttattggaaa tctttctgct gaggtgtttg gtgactatgt ttcaggtacc
    13981 aatcatacat taccaacact taaagcatca agatatactg gtggtgtttg ggttggaact
    14041 tttatcaaaa cttgtacaaa gcagatattt aatgaaaaag ctatacaatc attagcacct
    14101 gtagctgaaa agctggcaaa agaagaggga ttatatgcac atgcaaaggc tgctgaggtt
    14161 aggtttaaaa agtagtaaaa aattttattt tggcagtcga gatttagtat tagactgaga
    14221 taaagaaaac gctgagaacc tgaataaata ctatattttg tgggcctcgg cgtttctttt
    14281 atatctgtat ataataggat aatactacct gtgtgtttaa atgctaactt aatatttctt
    14341 ttctaaataa tgtttatgaa atagttaata tttttagtta atacttgaaa aaaacttttg
    14401 ctaactgtgc aaattcatct gcatttgtca atatagcagg gtgtcctccc tgactaaaaa
    14461 tgtgaatact tgcttttgaa ataaaagttg ccatttgctt gtactcttct tcaagattat
    14521 gacgacacat ttcgtcttcc ttacttcctg taaataaaat tggcatttct aatttacaca
    14581 attctttatg aaataaaggg cgtttcttgt ttgcacattg caatagagct tttgtatcaa
    14641 gattaacaac attctcccaa tcttttccat gacaccattc atagaatttt cgtgcttgaa
    14701 tatcttgctt tgatttttcc cttccagtga ttagattatc tatgaagtta tcattaagag
    14761 tacgtccatc aaagctatct gctataattg cttcaactaa atcgggacgt tctaatccag
    14821 tattaacagc tgcccatgct cctccacttg ttccaattaa gccaacttta ccacaattca
    14881 aatgttcaat cagtgctatt gtctgtaagg cttcatcatg ccatatgtca ggagaaaatt
    14941 gagaaactct atcagactgt ccattaccta aaaaatcaat taagatacat ctaaaatttt
    15001 ctacatataa tggcacaagt gctttaaaca tattagaaga accagtatta ccatgcagga
    15061 aaattatcgg tttaccttgt ccatattctt tataaaaaca agaattacct tgatactgaa
    15121 aatatgacat atattttcct cctttttatt tgttaagtta attataacaa tataggtatg
    15181 aatgaaaaac ctcatgttct ttcttagaat aaaaatgtgc cacgcataaa acgtgacaca
    15241 tttctaatta taaattttgc tgtttaagta ttctttgtat gcttttctct gtcaaaaagt
    15301 atttctctga taactgcttg atactcattc cattttggaa atttatacag atttgagaat
    15361 tacgagaagc taagacttgt ttggtgtttg tgttttcacc ccaatgcttt ttgtgctctt
    15421 gctttttggg aatataaatc actttaccat ctatatattc ttgcacttgc tcaatcagtt
    15481 ctttaggcag taagtcaatc gaattttgat agctcatttt gcacctccta aataattact
    15541 ctttaggatt agcaaaggct actgctactc acaattaaaa ataaaatttt ttattatgta
    15601 caatagcctt tgctatgcac aagttccaat tcccataaac taaatactcc tttctggttt
    15661 gaaaaattca tctgaacatt gatttcgatt ttaagataga gttcaatgac aaatttacat
    15721 ttttattata tatattcaga tagataattg caactgtctt tgtatgagga tattttatta
    15781 tagtcaatac tataatatat atttatatca tcaaactaat atgaacagtt gaaaggaata
    15841 tgaacaataa aacttagtca ggaagaataa ttatgaagca gacaattgag aaatttgatt
    15901 ttaaagtttt attgaaaatt tattgacaaa tttaacttgt aaatattata ctaaacttaa
    15961 taaataaagt ttataaagta aggtgttgtc tatgaaaaat atagttggaa aaccgcaaac
    16021 gataaaaaaa gtaaatgaag atttaataaa aaacattata aaaaatgaag gtcctataac
    16081 aaaaccagaa atttcaagca ttactgaatt gagtttagct acagttaata agattgtgga
    16141 gcaattagct ttgaaaaatg aagttaaagt aagtggacta agtgaatcta ctggaggaag
    16201 aagagctcaa ttatttgaaa taaatgcaaa cttagaacac ataatagctt tatattatta
    16261 tagaaattgt tgtatagggg tagttgccaa tttattaggt gaaataattt atcaagaaga
    16321 atttaatata agaatggata catatgaaaa cgttaaccaa gatacttttt ttgttataga
    16381 tactctaata aaaaaggaaa aaggaaacaa tataagggct attggaattg gtgtcccagg
    16441 agttgtaaaa aaaggtgtag ttaaaaatat accaactata aaaagttggg aaggtataaa
    16501 tttagaaaat ttaataaaga gtaagtacaa tactaaagtg tttatagaaa atgatacaaa
    16561 tattactact attgggattt atcaaaaaca gtataaagac aaatataaaa atatggctct
    16621 tatgtattta gaagatggta ttggttcagg tatagttata aatggtgaat tgtatttagg
    16681 ttctacaaat tttgctggag aattaagtta tctaaatata gaatttggta agtataactc
    16741 taacaactta aatcttgaag attatattat gagtttaaga aaaagatatt tagaaagtaa
    16801 agataataaa tttaagaaag aaattttatc tataatatca aactttataa ggactcttgt
    16861 atgtgtccta aatccacaag ctatgattat acagtgtagt atattaacca agagtgacat
    16921 ggagtttata gaaaaagatg taagtaataa tgttggagaa gaaaattttc ctaaattaat
    16981 aaaagtagag tcattgagag aaagaagtat aaatggagta attagtatgt gtttaaaaga
    17041 aactgactat caatattcct tatctaataa aaaaggagga tattaatgtg aaatatttgg
    17101 tttcaataga tggaggggga acaaaaacta aattttgtgt aagtgactta gatggaaaca
    17161 tacttaaaga acataccact ggttcaacta attataagtc agttggaatt aaaaaaacat
    17221 atgaaaatat taataatgga cttaaaaaaa tattaaaaga tttatatatc gattatgacg
    17281 atattgagta cactgtattt ggtatatctg gttgtgattc tcctaatgat tataagatta
    17341 taatggatga aatattaaaa attgggatta acaaagaaaa aatatatctg gcaaatgatg
    17401 cagttttagc tttttatgca caagctgatt cccctggttt agtaattgtg gctgggacag
    17461 gttcaattat actgggaatt aaagaagatg gagaaatata tagagttggt ggatgggggt
    17521 ataattttag tgatttgggt tctggatatg atatagggag aaaattatta aagaaagtat
    17581 tgctttattg tgatgaatgt catgagtata gtgatttatt tagttgtgtc ttggatttct
    17641 ttggagcaaa tagttttgaa caacttgcat atatgattac tgatataaac aataatgttg
    17701 aaatagcaaa cctagcttca ttagtgattg attgtgccga acaaggtgat aaattagcta
    17761 ttgaaatatt aagagaatca tcaactgaac tatctaaatt agctcaagta atattgagaa
    17821 aaatatctaa tccaatgaaa atagataaaa gcgaaataaa tatagttttg tctggtggta
    17881 cattaaataa aactgtatat gctcaaatgt taatgaataa tttaaaaaca gaaaatacag
    17941 ataaaaattt aaaatttata tctcaagaaa atcagccagt atatgggggg ataagacttg
    18001 ctatggcatt agctaatagg agagttaagc atggatagaa aaaaggtaat agtacaaatt
    18061 tttactggag gttttaaggc taaagaaata aagtttaatg atataaaatg taaactacta
    18121 gaattattgg actgtattga tatagaaaag gttatcatgg gatggagtgt agatgaagaa
    18181 ttatatgtag aaactaaaaa actattaaat aaatataatg ttgaactata tctttggttg
    18241 ccatgttttt ctgaaatagg attacttgaa aaaagtaatt tactaattga ttatatgggg
    18301 aaggaagtca agggctatgc tttacaagag gatgaaaatt ttgaatttta ttgcccaaat
    18361 aataaggaaa atataaaaaa tataaagaaa atatatagta cttattttag tgatattaaa
    18421 tttgatggaa tttttttaga taaaataagg tatggttctt tttcgaataa actaaatggt
    18481 gtttttaatt gtttttgtaa agattgttta aatatatatg aaaaaaataa tattgataaa
    18541 aagtcgttaa tgagagaaat gaataatgtg tctaagggag ttatagataa tgaagatact
    18601 ccatctggta taacagaata cattaatgga aaatacaaat ttaaaaataa aatatgggaa
    18661 gatttttttg aaacaaaaaa tcaaaatata tacaagtcat tattagagat aagtagttat
    18721 tttaaaagta agggattgaa aataggtata gatacttttt ctccttttat ttcttacttt
    18781 acaggtcaag atttaaaaaa attacaagaa gtagcagatt ttataaaacc aatgatgtat
    18841 agaactacaa aagctccagc tggtttacca tttgaatttg aaaggtttat tgatgaatcc
    18901 atacataaga ataaagagat tggaaaaaga aatttcttag atattttagg aattaaagag
    18961 tatgaaggag atgtatatcc tatagaattt gtactagagg aaatcgattt tatgacaagg
    19021 aatcttaata aagatatata tgtaggagtt gaaataaata aaaaggaaat tatagctcct
    19081 gttacaccta agtacataag tgaaaatatt tcaaatataa ataagacaac agtaaaagga
    19141 tatgttttat cttgggattt gttatcagca ccaaaagaaa atattgatga aattataaaa
    19201 tggtttcgga attagtgagg tgatatagtg agtaagatat tagaaatgca acaaatatat
    19261 aaaagttttg gaaaggtaga tgttttaaaa gggataaatt ttgagttaga aaagggagaa
    19321 gtaagagctc ttttgggagc taatggagca ggaaaatcta cacttattaa aattttagga
    19381 ggagttcatt ctcaaactaa aggtaaagta attttgactg gtaatgaaat aatgtttaaa
    19441 aattcacatc attctaaaga aaatggtatt agtataattt atcaagaatt aagcttgata
    19501 ccaacgctta cagtacttga aaatattttt cttggtagag aaattttaaa aggaagtgtg
    19561 tttttaaaca agaaagacat gcttgaggaa tatatgaaaa tttgtgagga ttttgatttt
    19621 aatatagacc cacatacagt agtttctaat ttaagtgtag caaaccaaca aatggttgag
    19681 ataatgaaag ctgtttcatg taattctgaa attatcataa tggatgaacc tacaacatca
    19741 cttactaata atgaaaaaga tgggctattt aaaataataa gtagactaaa gtctaaaggt
    19801 aaaacaatag tctatatttc tcacatatta gaggaagttt ttaaagtatg tgatagtgca
    19861 agtataatga aaaatggaat tatgattgga acttatgatg tagaggattt aactaaatta
    19921 aagataactc aacttatgac aggaaatgat aatcacaaac ttattgagaa gaaggattat
    19981 acatttgcaa agtatgaaga gccaccagta ctagaagtaa agaatataag ctggtctaac
    20041 aaaataaaaa atgtttcatt taaagtttat agaggcgaag ttgtaggtct tgctggtctt
    20101 gtaggttcaa gaagaactga aattataaat ttgatatttg gtatagataa taaagatagt
    20161 ggagacattt ttatcaatgg taaaaaagta gacataactt ctcctaaggt tgctataaaa
    20221 aacaaaatag gattgattcc tgaagataga aaaaatctag gattaatttt agaacaagct
    20281 atatacacaa actcatcatc agtacaaatt gataaattca agaaattttt gtttatagat
    20341 agaaataaag aaattgagtt ttctaaaaaa ggtgttaagg aattaggaat aaaagttagt
    20401 gatgtaaagc aagaagtaaa agagcttagt ggtggaaatc aacaaaaagt agtagtttct
    20461 aagtggttag agaaagattt agatttaata atatatgatg agccgacaaa gggaatagat
    20521 attgctgcaa aagaagatat tttcaataca atcaaagaat tttcaagtga aggaatagga
    20581 gtaatattta tatcttctga tttagaagaa gtaataagag taagtgatag aattttagta
    20641 actagagaag gttctattgt agatgattta aaaaatgaga atatacaggt tcaagatata
    20701 atgaacagta tatttaatgt ataaaaaatg aaaatggagg actgagatga agaaagcttt
    20761 tgagaagtta aatttaagag attatggagt attattaggt tttttagctt tatgtatagc
    20821 tataagtatt gcaactccat catttttagg taaacaaaat atacttaatc ttttacgaca
    20881 atcttctata attggaataa tttcagcagg tatgactttt gttataatat ctggaaactt
    20941 tgatatatca gttggagcag tagcagctct tgcaggtgct ataacaatga aatttgcgac
    21001 tggtggaact aatttgtttg catccatgct cttaggtgta gcgatttgtg cagtaatagg
    21061 attaatcaat ggtatagtag ttgcaaagat aaatgtacca tcattaatag caactatggc
    21121 tatggtcact attgtaagag gattgctgtt gatgcttaca ggaggatatc caattactga
    21181 aaatatacca atacttgatt acattggaaa tggatatttg tttaatatac caataccagt
    21241 agtaattttc tttatagtgg tgttagtttc atttattgta cttaataaaa ctaagtttgg
    21301 tagatatgtt tattctgtag gagggaatca agaagcaagt aaacttaatg gtataaatgt
    21361 agattctcac aaagtgaaag tgtttattat taatgctgta cttgcaggaa tagctggaat
    21421 cgtactaaca ggaagacttg ggactgcaac tgctattgca ggtgaaggat atgatatgga
    21481 tgcaattgca tctgtagtaa taggaggtac atcagtggca ggaggttctg gttctgtact
    21541 taaaactgtt ataggagtat tacttatgag tgttataaac aacagtttta atcttcttgg
    21601 aatagatgta tatttccagt acatatttaa aggattaata attttagcag cagttggatt
    21661 tgattcttat agcaagaaaa aacttgcttc aagataaaaa ataaggggga tttttttatg
    21721 aaaaaattaa tgaaacattt agcattgttg ttatcacttg ttatgatatt tggtttagtt
    21781 ggttgttcaa atggtggtga caaagaaaaa aatggagaaa agaaaatagc agtattacta
    21841 ccaggttcaa caggttactt tgtagcaact aaacaaggta tagatgcaaa atctaaagaa
    21901 ttaggtgtaa gcgtggaata tgcagatgct caatgggatg ctagtaaaca attatcacaa
    21961 gctgaagatt ttatggctaa aggggtagac atgattgcat tatgtggagt tgattctgct
    22021 gtaagtgaga gaatagttaa agctgctaat gattcagacg tccctatagt agcatttaca
    22081 aattctatag gaagtaaccc aactggagaa tttaaaggtt tagttacata tataggacaa
    22141 aatgaggagg aaacaggagc actaactgga aaaattgcta aaaacttatt aggagaaact
    22201 ggtgggaaag ctgtattaat agaaggagta ccaggaacta ctccacaagt attaagaaaa
    22261 aaaggtcttg aaaaagaatt aaaagatagt aatatagaaa tagtttataa tcaaacttca
    22321 aattgggaga aagagcaagc tttaaaagta acagaagatt taattcaaaa gaaaactgat
    22381 tttaatgtta taatatgtca agatgataat tctgctacag gtgcaggtca agctttaaaa
    22441 gatgctggtc ttaaggataa agttaaagtc ataggtttgg gtggaagtaa agatggatta
    22501 aaagctataa ctgatgggtt aatagatggt acaacttata tgtctgctgt agaagaaggt
    22561 ggattagtca tagaaaaggc atctaaattc cttaaaggtg aaaaaataga acctgttaca
    22621 caaattaaac aagttgaagt taacaaagat aatatttcag agttcaaggg tgaatggtaa
    22681 attgtcatag ataataaata agatttttag agttacttta gaaactatat aaagtaactc
    22741 tttttttaat ttaatttagt gataaattat tgaatagtat ttctaaacaa ataaaaaatt
    22801 aatataaaca aagacttaat tatactaaat tataagtaaa actaatataa acttatggaa
    22861 aaaaggaaaa cgtctaaagt attggaatta ctatagtgta ggtgtggtat taaaaaaaca
    22921 taaaaaaaca taaaaaaatt gttgaaaaaa atatagaaat tttgtataat taaagatttg
    22981 aaaagttcgg tatacaaagc caattctttt gtatataata tatataaatt cagaaaaagg
    23041 aagggatatg tatggccagg cggttatttt tagaaaggat tggacttata tttttaggtt
    23101 cagcaatatt agcatttgga gtttataatt tttattattt aaacaacata acagaaggtg
    23161 gagtgttagg tattttacta ctgttaaaaa atttattcaa tatacaacca gcaatagcaa
    23221 atgttgtaat agatggttta ctacttttag taggatataa atttttcggt aaaaaattcc
    23281 ttatatattc aatagtagct tctataactt tttcagtgtt atatgactta tttgaagcta
    23341 taggacctct agtaccacaa tcacaaaata tgcttttatc aactattttg gcaggtgtaa
    23401 ctgttggaac tggtgtaggt atagtagtaa aagcaggttg tgcatcagga ggagacgatg
    23461 ctttagcatt agtaatttct aagactacat ctttgaacat agggcaagtt tatttagcaa
    23521 cagatgttat tgtattgttg ttatcattat tttatctatc agcgtttgat atcttttatt
    23581 ctttgattgc tgttacaatt agtggcaagg taattgattt tatttattat catggtaaaa
    23641 gtttggatat ggatataagt aatgatatag ttccagaatg ttaatataaa ttaaataact
    23701 ttagatttta ttaggggtgg cagatttgcc accttttttg tgtctaaatc tttatagaaa
    23761 gtataatccc atctaggttt ttgcaaatct caaatataga attatgttgg aatgactggg
    23821 aatacgattg ctagatgtgc attttaaaaa cccaatttta tatttatgaa atactaatca
    23881 ttaatggatg tttcttaatc ctatctttat acctaaaatg ataagataaa tgaagtagca
    23941 atacaaaact aaaatttgta aaagagatta aattaaatgg aggagctaaa atgttggata
    24001 tagttatgat agcattgtta ttcataggat ttgtttccat gaagttactt gctgattggt
    24061 gtgggaaaca aactgagaaa aaataatgta atgtatggag ggattaccta tgtggtttct
    24121 ggcagttgta attataatgt taataatata tttggtatat gcgcttatta atcctgaaaa
    24181 attttaaaca gtataaggct aataagtaag ttgaattggg gggaacaatt tttatggtgc
    24241 agatagtaat agtgttagcg atttttatga ttttagtaat acctatgggc aagtatttat
    24301 atcatatagc tactaatcaa aaaacatttg gagatagact atttgataaa gtggacaatt
    24361 ttatatataa ggtatgtagt atagataaga aaaaagaaat gaactggaaa cagtatgcat
    24421 tagctttatt atttacaaat gcagttatgg tatttatagg atatatcata cttagaactc
    24481 aaagtatgca tatttttaat ccaagtggaa ttaaaagtat ggaacaagga ctatcattta
    24541 atacaataat aagttttatg acaaatacaa atcttcaaca ttattcaggt gaatcaggac
    24601 tttcatactt tagtcagatg acagtgataa tatatatgat gtttacatca gcagcaacag
    24661 gatatgcggc tgctatggca tttgtaagag gtctagtcgg taaaaagaaa acattgggaa
    24721 atttttatgt agatttaatt aggataacaa caagagtact tttaccagga gctttaatta
    24781 ttgggcttat attagttaca caaggagtac cacaaacttt tgctgggaca gaaacagtga
    24841 ctactataga aggaaagctt caagatatag ctagaggtcc tgtggcagct cttgaatcaa
    24901 taaaacattt aggaacaaat ggtggtggat tctttggttc aaattcatca cacccatttg
    24961 aaaatccaac aataatatca aatatagtag aaatattatc tatgatgata ttaccaggag
    25021 cttgtgttgt tgcattcggt cacatgataa agaataaaaa acaaggttgg gttgtgtttg
    25081 gcgcaatgtc aatcatattt ttaataggtc tagtagtgtg ctttaaagca gaaagtgcag
    25141 gaaaccctat tttatcacaa ttagggctta atcaaagtat gggaagtatg gaaggtaagg
    25201 aagttagatt tggtatagca caatcatcat tattcacaac agtgactact tcctttacga
    25261 caggtacagt taataatatg catgatacac tgactccttt aggaggatta gtaccacttt
    25321 taaatatgat gctaaatgta gtatttggtg gtaaaggcgt aggtctgatg aatatgttga
    25381 tgtacgctat aatagcagta ttcttatgtg gattaatggt aggaagaaca ccagagtttt
    25441 taactaagaa aatcgaagga aaagaaatga agcttattgc tttacttatt atattacatc
    25501 cacttttaat actaatgttc tctggtcttt cagtagcaat accagcaggg cttgaaggaa
    25561 tttcaaatcc tggattccat ggattatcac aggtattgta tgagtttgca tcttcagcag
    25621 ccaataatgg ttcaggattt gaaggtctag gagataacac tatgttttgg aatataacaa
    25681 caggtatagt tatgttcttt ggaagatatg tgtctattat agtactacta gcaatatcaa
    25741 gtttgttagc atctaaaaaa gctgtaaatg aaagtatagg aacacttaga acggataatt
    25801 ttacatttac aatagtttta gtacttgttg ttttaattgt tggtgcttta acatttttcc
    25861 cagccttagc gcttggacct atttcggagc atctagtgtt gtggcactaa aaaattggga
    25921 gggagtaaag ttttatggaa actaaaaaaa caaagtttat tacaaaagat attttcaaaa
    25981 cttccattat agaagctttt aaaaaattaa atcctaaata tatgatgaaa aatccagtta
    26041 tgtttgttgt agaaattgga tttatagtaa cattgatact tacaatagta cctagtttgt
    26101 ttggtgatga aggcaataat ttaagagctt ataatgggat tgtaacaata atcttattta
    26161 taacagtcct ttttgcaaat tttgctgaag ctgtagctga gggaagaggt aaagctcaag
    26221 cagatacact taagaaaact agaaaagata cagtagcaag ggttatagat acgttaggaa
    26281 atgaaaaaat gataagtgca agtgagctaa aacttggtga tattgtttta gtaaatgttg
    26341 gagaagttat cccaaatgat ggagaagtta tagagggcat agcttctgtg gatgagtcag
    26401 caataactgg agaatctgca cctgtcatga gagaatcagg tggagatttc gcatctgtta
    26461 caggtggtac tacagttgta agtgactggt taaagataag aataacaaca aaaccaggag
    26521 aatcgttctt agataaaatg atagctcttg tagaaggtgc ttcaagacaa aaaacgccaa
    26581 atgagattgc tttaaatact ttgttagtag ggttaacact tatatttatg gttgttttaa
    26641 tatctcttta tccaatggca aactatgcag gtgtaaagat tccaatttct actatgatag
    26701 ctcttttggt atgtttaata ccaactacta taggtggatt gttgtcagct attggtattg
    26761 caggtatgga tagagtaact agatttaatg taattgcaat gtcaggaaaa gcagtagaag
    26821 cttgtggaga cgttgatact atgattttgg ataagacagg tacgattact tatgggaata
    26881 gacttgcatc agaatttata gcagttggaa atgcagattc aaaagattta ataaattatt
    26941 ctgttatgtg ttcattaaaa gatgatacac cagaaggaaa atctatagtt gatttaggta
    27001 tgaaattagg ttcaacaggt aagacaaaag aggcagagga agctgagttt gtagaatttt
    27061 ctgcacaaac tagaatgagt ggtattaact tagctgatgg tagagctata agaaaaggtg
    27121 cttatgatag cataataaaa agagtaaaag aatctggtgg tacagtgcca gaagatttag
    27181 aagaaaatgt aaatcgagta gctaaactag gaggaacacc tttagtagtg tgtgtagata
    27241 atgagatata tggaattatc tacttaaaag atacagtaaa atcagggctt gtagaaagat
    27301 ttgctagact tcgagagata ggaataaaga caataatgtg tacaggggat aatcccttga
    27361 cagcagctac aattgcaaga gaagctggag tagatggatt tattgcagaa tgtaaaccag
    27421 aagataaaat agatgctata aaaaaagaac aattagaggg taaaatagtt gcaatgacag
    27481 gtgatggaac aaatgatgct cctgcacttg ctcaggcaga tgtaggtctt gcaatgaata
    27541 gtggtacaac atctgcaaaa gaagcagcaa atatggtgga tttagattca gacccaacta
    27601 agatattgga agttgttgaa ataggaaaac agcttttaat aactcgtggg gctttgacaa
    27661 catttagtat agcaaatgat gttgcaaaat attttgcgat tataccggct atatttactc
    27721 ttgcaatacc tcaaatggag atattaaatg taatgaaact ttctacatca tttagtgcga
    27781 tattatcagc tttaatattt aatgctataa ttatcccatg tttaatacct cttgcaatga
    27841 agggagtaaa atatagacct atgaaatcac aagctatgtt aatgagaaat atgcttatat
    27901 ttggtcttgg tggagttata gtaccatttt taggaataaa attaattgat ttattgatta
    27961 cacctttagt aatgattctt aatttaggtt aataaatgga ggatataaaa atgaaaacat
    28021 taaagccagc attacttgta agtattgtat tgttagttgt ttgtggactt gtatatccac
    28081 ttgttttgac aggtgtaagc caagttgcat ttaaagataa agccaatgga agtatgatag
    28141 aagtaaatgg tgtaaaagta ggttcagaac ttattggtca aagctttaca gatgcgagat
    28201 tctttaaggg aagagtatca tcagtaaact ataatactta tacaaaagaa gatttagtac
    28261 cagataaaga tggaaatgca tcttatggag gtgtatcatc agggtctttt aattatggag
    28321 ctacaaatcc agaacttcat gatagagtac aaaaagatat agaaaagttt ttaaaggata
    28381 atccaactgt caaaagagag gatataccaa cagatttact tacagcatca ggttcaggac
    28441 ttgaccctaa tataagtcca gcctctgcaa aaattcagat accagctata gcaaaagcgt
    28501 ctggaatatc agaaagtaaa ttacaaaaaa ttgtagatga taatacttcc aaaaaacttt
    28561 ttggagtttt aggtgaagat agagttaatg tactaaaggt taatatagag gtcgcaaaaa
    28621 tattaggtct tatatagtat tttgtggaat tttagtaaca aaatattact caagatttaa
    28681 tttaaaggtt aaattttaaa gagtgaaaat caataatgat tttcactttt ttatttgaat
    28741 attactaata tttggaataa agtgattgta agtataaaat ccaaaaaaag gttgcattat
    28801 caaaatgata atactataat atatttatcg ttatcaattt gataatagat ttggacatat
    28861 aggaggaaat agtatgttat ataataacgc attagagttg ataggaaaca cacctgtagt
    28921 aaggctgaat aatttaggct gtactaatgg gtgttctaac atatatgtaa aattagaaaa
    28981 agtaaatcca gcaggaagta taaaagatag agctgtttat gaaatgttag agggcttaga
    29041 gcaaagagga gaattaaaaa agggagatgt actagttgaa gcaactagtg gaaatactgg
    29101 tattgcatta tctatgatag gaaaattaaa aggatatgaa gtagtaatcg taatgcccga
    29161 aacaatgagc gttgagagaa gagatttaat gaaggcttat ggagcaaatt tggtgcttac
    29221 agatggtaaa gctggaatgg caggttccat agaaaaagca aatgaacttt taaaagaaaa
    29281 tccaaactat aaaagcttaa aacaatttga aaataaagat aatccaaatg cacattataa
    29341 aacaacagca gttgaaatta tgaatgatgt caaagattta gatatattcg tatgtggagt
    29401 tggaacaggt ggtactttaa taggaactgc aagatattta aaagaacaaa atccaaacat
    29461 aagagtaatt gcacttgaac caaaaaaatc tccagctata tcagaaaaca agactggacc
    29521 tcataaaata caaggaatag gtgctaactt tgttcctgaa aattatgatt ctagtgtagt
    29581 tgatgaagta atattagtag atgatgaaga tgcatttgat acagttaaat tacttgcagc
    29641 aaaagaggga attttagtag ggatatcttc tggagcaaat atatttggtg ctatagagat
    29701 ggcaaaaaag tatccagata aaaagatagt tacagtagct ccagatggag ttgataagta
    29761 tatgtctatg ggaatatttt aataatttta tttgagggag tgaatacttt gtttaagaaa
    29821 ataaataaag atattgaata tataatgaag aatgatccag cagctaggtc taagatagaa
    29881 gtttttttac tttatccatc agttcatgca atgataatgc ataggatggc tcatgctctt
    29941 tataagaaga agaagctttt tacagcaaga ttaatatccc agatatccag atttatgact
    30001 ggcatagaaa ttcatcctgg tgctaaaatg ggggaaggta tattgataga ccatggaatg
    30061 ggtgttgtaa ttggagagac agctgaagta ggtaataggg tgacaatata tcaaggagct
    30121 actttaggag ctacaggaaa agatactgga aagagacatc caactgttgg tgatgatgta
    30181 ttaattggtg ctggaacaaa aatactagga cctttaaata taggttcaaa ttcaaaaatt
    30241 ggtgcaaatt ctgttgtcgt taaggatgta cctaatggtg caacagttgt tggtatacca
    30301 gcaaaaatag taaaaataag aaacctagaa cctgtaaaaa agaataaaaa agaagtgtcc
    30361 tatgagtatg atgaattaga taatgtatat tatatatagg atttatataa ctataaaata
    30421 aactttataa aaattatttt aaaaggtatt tttttcaaat ttgaggacat aataaaaaag
    30481 aactgaatgt tacagttttg gttcatcaat ctttgataaa caagatttta aatttgtagc
    30541 gtctaggagg attttattat gaaagcaaat gttaatcaag atacttgtat aggttgtgga
    30601 ttatgtccat caatatgtcc agaagtattt gatatgaagg atgatgggaa atcacatgtt
    30661 atagttgatg aagtaccaag tgatgctgaa gaatcagcag cagaagctag agaaagctgt
    30721 ccagttgatg caatagatgt gcattaataa aataaatgcc tataaaaatt gaattttcaa
    30781 tttttatagg catttgtctt ttattcagtt agtatttcaa cccctgtttc tgtaactaaa
    30841 accatacatt cccattgagc agataattta ccatcttttg tataaatagt ccaattattt
    30901 tcttcatcaa caaaaatttc gtgagttcct tcatttacca taggttctat tgtgaatatc
    30961 atcccaggaa ccaatagcat ctcagtccct tttttagata cataacttac aaaagggtct
    31021 tcatgaaagc ttaatccaac tccatgacca cctatttctc taacaacaga gtatccattt
    31081 ttctttgcat aagagttgat agcatcacct atatctccta aaaatcccca tggtttggca
    31141 acttcaagac ctttttggac acattccttt gtaacttgaa ctaatttttt tgcattttca
    31201 ttaacattac ctatcataaa cattcttgaa gcatctgaat agtatccatt aaaaatagta
    31261 gaaacatcta catttataat atctccatct tttaagataa tgtccttgct tggaatacca
    31321 tgacaaactt cattatttac tgatgtacat acacttttag gaaatccatt atagtctagt
    31381 ggagcaggga tagctccatt ttgtagtgta aagtcatgaa ccaacttatt catatcttct
    31441 gtagacattc caatttcgat tttatctgaa atataatcca aaatttttgt gtttattaca
    31501 gcactttttt ttatttcctc aatttgactt tcatttttta taatatcatg agttggtaca
    31561 atatgaccta acttagcaaa tgaatctatt ttattatcca tatccatatg acatttttta
    31621 tattttttag tacttccaca ccaacagcta tcatttctat ttaacttcat aacttttcat
    31681 ccttctttta ttatttattt aaattatggg ttacataaac tattttaaaa cataaccatt
    31741 ataaatatta taacataaat actaagaaat cctttataga tagtgattta ttcaaagtat
    31801 aaattattat atggttattg ttgatgaaaa gaggatagtt aaatgtatta ttggatatta
    31861 gcgcacttaa tagtttagtt caagtttttc aagaaaatca tatgttagag gacaattttc
    31921 ctttaaagta ttttttgaat cttcatcaag ataataatgc acaaatgatt ctgcaaaaaa
    31981 ttcttctata aacttgctta tatatgcatg tgcaacttgt ttagggtcat aaagcttata
    32041 tctttcctga gcaaatactt ccataaattc ttcagaattt gattttttat ttaaaacatt
    32101 tttatctata gcatgtgcag tttcatgtaa ttctaaattt tttgatgaat gtacatttgc
    32161 atagctaggg ttactataac ctattttagc tactatagaa ttatttctat atataccagg
    32221 tacatctttc caagtcttgc ctgatcttac ccaacatgga ggtaattgat attttaaatc
    32281 actaaattct ggttcatcag ttagatttga atttattaat tttattttta tatccttttc
    32341 tttaagtgtc tgtaaatatt taatatttat ttttgcaagt ctgcttttca tattttcaac
    32401 ttcatcttta tcataattca agtcatcagg aagtataagc atttgttcaa ttatatctat
    32461 gctactgtct tttatatctt cagattcttc atcaaattta tattgaagag tattattttc
    32521 atagatagtt atatttgtat tattttccat ataataagag tgaatatcct ctaagtctaa
    32581 aatattcatt tgttgtaaaa tatgttttgt ttcgccactc catactacta aagaaagtga
    32641 attaaaatta attagtggat tttcctttgc ttttatatca ttgcttatat ctacatcaaa
    32701 tacatattca attgagtctt ctatgttaag actatctgta ttctttttaa tatataaata
    32761 tgcttgtttt aagtctatat aaatctcatc taaagattca tcataaaatt ctgataaatt
    32821 attagtaaag agttcttcac ttaaaagttc atttttatca gttatacttt caattaaaat
    32881 attaatttct tttatcatat cgtaaatact tatttttcta tttgcttttt cactagatac
    32941 attgcatggc gcaagagcaa tgcaataaaa atctttttct tttttataaa aggctttaag
    33001 tgattttgat aaaagtgtaa agtctacacc tatctgtaag ttgaccttaa gtgagtcatt
    33061 ttgtaataat tcagtattat tttttttagc tatatttaaa ttgttttcca taatcattgc
    33121 ccccttttta ttagggtatc ataatttttt tatatgtgtc aatttgtttt tttgaaaatt
    33181 ataatttttt tgaaaatttt attttttata atttgtgaat tttttattat agaaataaat
    33241 atgttattat tatgtcaaaa tttagcatta gattcatgta gagtatgttt tatacatata
    33301 ttataattaa ttctttgaag attgcatatt caaaatacac accatttttt ttaattctat
    33361 aatataatat ttatatattt aatgttagga tgtgatttaa ggtgtatttt acatatatta
    33421 taagatgtaa agatgattct ctatacactg gatataccag taatatagtt agaagaatga
    33481 atgaacataa gttaggaatt aattcaaaat acacaagagc aaagggattt gaaaaactag
    33541 aagtttattt tgtgaccaac acaaaaagca atgctatgaa gttagaatac tatataaaaa
    33601 aattaactag aaataaaaaa ttgtctataa taaaaaaccc aagtatactt ataaatttaa
    33661 ttgataataa agaagattat attattggta aggaaataga acaattaaca taaatattta
    33721 tagtaacatt ataatgggtg catatagtgt aaaaacttga caataaatac tattgtaata
    33781 taatgaagtt ataaatatag taaattaaaa tagctagggg agccaagagc tgagaggtat
    33841 accgaccctt acacctgatc tggataatac cagcgtagga aagcttagta aaaattcaag
    33901 tatgtattat ttgtgatata tgctatttct aagctatacc tattgtaggt atagcttttt
    33961 taattaagtt atttaaatta aactttagga ggcaacaatg agtaattata aaataccaac
    34021 acttacaata gctggctctg attcatctgg aggagctggg attcaggctg atttgaaaac
    34081 gtttagtgca attggtactt atggtatgag tgtaataaca gctataacag cacagaatac
    34141 taaaggagtt tttgctgtag aggatttaaa taagaaaata ataaaaaaac aaatagaggc
    34201 agtctttgaa gatatacctc caagagctgt aaaaatagga atggtttcaa gtcctgagat
    34261 tatacttgaa atagttgaga atctaaagaa atacaatcca aaatatttgg ttgtggaccc
    34321 agtaatgata tctaaaagtg gatattatct attaaagcca gaggcaaaag aaaacttaat
    34381 taagtatttg ataccacttg catacataat tacaccaaat ataccagagg cagaagaaat
    34441 aacaggaata aaaatacata atgtagatga tatgaagaga gtaggagaag aaatactaca
    34501 acttggacct aaatttgtac ttatgaaagg aggtcattta gatggagaag cagtggatat
    34561 tttagttggt aaaaatatat ttaaagttta taaaagtgaa agaattgata aaaaaaatac
    34621 acatggaaca gggtgcacat tatcttctgc aataacatct tatctagcat taggatatga
    34681 aataacagaa gcagtaaatc taagtaaaat ctatataaca gaagcaataa aaagaagttt
    34741 tgatataggt catggagtag gaccagtaca tcatttttat aaatttgagt aataaaaaaa
    34801 tattggaggt agaatatgta taatttaatt aaagatgtaa aaaaattaaa tccattggta
    34861 attcattata ctaataatgt aactataaat gattgtgcta atgtgacttt agctgtagga
    34921 gcaagtcctc ttatgagttt ttcatatgag gaagtagaag aaatggtaag tgtagcaaat
    34981 tctgtagtaa taaatatagg aactatgaac tcaaatatgt tggatttatt tctattagct
    35041 ggaaaagcag caaataagta caataaacct gttgttttgg acccagttgg agtatttgca
    35101 agcaaagcga gagcagaact tacaagtaga cttttaaatg aagtcaaatt tagtgttgtt
    35161 aaagggaatg tatcagaaat aaagtttata ggtggcttta atgtaagggg taaaggtgta
    35221 gattcatttg atgaagaaga agattctact gagataataa gaaagattgc tgaaaagctt
    35281 gaatgtgtag ttgtagcaac tggaaaaata gatataataa ctaatggtaa aggtatatat
    35341 aaaataaaca atggaactga taaattaaaa ggaattacag gaactggatg tatgactgct
    35401 agtttgattg caagttttat ggctgttact gagaatatat tagaagcagc aacaatgggt
    35461 gttcttacaa tgtctttaag tggggaatta gctaatttaa ataatccacc aataggtaca
    35521 tttaaagaaa atcttatgaa tgctatttat caaatggata tagatacttt aagtaaaaat
    35581 tctaatattg aatttttaaa ttaataaaga gtaagggaga cttaaaatga ttgataaaga
    35641 atctttaaaa aaatgcttaa agttgtattt ggtaactgac tctgaaatgc ttaaaggtag
    35701 agacttttat aaatgtcttg aagatgcaat atcttctgga ataacaactg tacaacttag
    35761 agaaaaaaat gcttctggaa gagagttttt aagaaaagct atgaaactta gagaaataac
    35821 tgaaagatat ggtgttaagt ttataataaa tgatagagtg gatatagcac ttatttgtga
    35881 tgcagatgga gtacatgtag gacagagtga cattgatgtg agagaggtta gaaagcttat
    35941 aggaaacaat aaaattctag gagtatcagc aagaacttta gaagaagcta cttgtgcaaa
    36001 aaatgatggc gcagactatt taggtgtagg gtctatattc acaacatcta ctaaattaga
    36061 tgcaaaatca gcttcgtttg aaactgttaa agaaattaaa gaaaaagtag acatgccatt
    36121 tgtgctaatt ggaggtataa atttagacaa tatagataaa cttaaatgtt tagaaagtga
    36181 cgggtatgct ataatatcag ctatattaaa agctgaagat atctctaaag aagtggaaaa
    36241 gtggacatta aaaatataaa attggctctg gtagtgaaaa aaatggaaaa atttgatata
    36301 atctaagagt aaaatttaag caattataaa tgataaactt ttctacatat actttttaat
    36361 caagatatat gtagatttgg ttaaaaagga gctataaatg attaagatat tgttagtgtg
    36421 tgttggaggc atgtcttcta ccctattggt aaataaaatg gagaaggatg caaaaaaaag
    36481 aaatatagac tgtaaaatat gggcagttgg agaaggagat ataaaatcgg agcttgataa
    36541 ctttgatatt ttacttcttg gaccacaact tagatttatg cttgatgacg taaagtctat
    36601 agttggagat agagttccag tatctataat agatatggta aactatggta cttgtaatgg
    36661 tcatgctgtg ttaaattcgg ttttagaaat attaaaataa ataataaaag tggattctat
    36721 ataatagagt ccatttttat tatttgttat taataggctt aaaacttagc ttaccatttc
    36781 tttttttaat ctccacatag caagtgaaaa acttgaacag cacaatatta aaaatagtag
    36841 gataacaggc agtatatctc caataagaat agtctcacca aatattaagc tacgtaaagc
    36901 gttaataaca tgggtaaatg gattgagcat cactgctact tttaatcctc cagataaact
    36961 ttctataggg aaaagagctg aacttaaaaa gaaaatagga agtacaattg cagtcataat
    37021 tgtttcataa actatttcat ttggcaataa taaacttata gaataagcta gacttgataa
    37081 aaagaaggct gtcataaata tcagtactat cataagtagg attccaccaa tgccagattc
    37141 tatccttact gagaagaata tacttactat acacaaaata gttacttcta tgaaggaaac
    37201 taagatagct tctaataatt gaccaaggac gattgaatac ctactgatag gtgcaattaa
    37261 gactctatag aaacttccac tgttcttcat tataaagttt ataataccac cactactaca
    37321 agaagaaaac acaaccagta caatgatacc tggtagtata aaagcagtat aattattgat
    37381 atttatatta ttcatagttt ggtttgcaat agaactataa agcacaagcc aaagaaaagg
    37441 ttgtaatata gtaactacaa atgagattgg atttttaaaa cgccacttca tactacgcca
    37501 taagatattt aacattccca ttcctccttt aagctttttt tagaacttgt aagtgctaaa
    37561 aatacatctt cgagacttgg ctctacaatt tctattgcat caaattctat atcatgttct
    37621 aaaagccatt tatttattaa agtaaaagca gttctactat cgtttacact tataaaaatt
    37681 gaattttctc gtacgctcat aaactttact aaaccagtac ttttaattga atctttatat
    37741 ttttttatat cttcagtatt atggaaagtt atacgtagta tattttgtct aatgtaacta
    37801 cgtaaacttg atggtgttcc ttgtgctaaa tcctttccat tcttcataat acaaatatta
    37861 tcactcaatt gttcagcttc ttcaagataa tgagtagtta gaaatatagt tgtgccgtac
    37921 tcatctctaa tttttaataa catatcccac atagattttc ttgaatcgac atccatacca
    37981 acagttggtt catctaaaaa taggatttta ggagatgata ccatattcat agctatgtcc
    38041 aatctacgtt ttacaccccc tgaatatgat gaagtaggat attttaagta actagataag
    38101 tcaaacttat caattaaaga gtctattctt tgttttgcaa tctgtggttc tactttatac
    38161 attttacttt gaaataccat attttccata agggataaat gttcatcaat agagatttgc
    38221 tgtgctacac aagcaatttg agtacgtatc caagaaggat tatctactaa atcttttcca
    38281 aacattttta catttccaga tgtaggtttg taaaaggtag tcaaaatatt tataagagaa
    38341 gatttaccag caccattagg accaagtaaa gaaaaaattt ctccagcatt tacattaaag
    38401 cttagaccat ttaaagcttt cacaccattt ttatattctt ttactaaatt gtctatttca
    38461 atcgctaaca tatattattc ctcctcttta agtggaaata ttatctctgt aatatagtta
    38521 tctgggtttc cttttatcaa catacctggt cctttaataa atacttctct ccaaggagtt
    38581 tgtattttta tattattttc atgaatatat ttaaatatca tttcatacgt ttttggcaaa
    38641 ttactataag agcctgtgtg agtaaaaaat aaagcttttg ttttaggaaa ttcttttgta
    38701 gttataccca tacgatttgg agtttcagca gttggaacac ataattccat ttctgcaaca
    38761 ccagtttttt ggtcaacatc atagtagcaa aagaatggtg caccgttaga ctttcctttt
    38821 atagctttaa atacatttgg aaaatacttt gttgcctcag tcataggtcc attataacgc
    38881 atggtagcca ctgtgactga ttcgatattt ttgatttcaa ttttgcaatt catttgttta
    38941 cctcctaatg tgtgttcata ttcttactag atttttaagc attaatacat ataagatttt
    39001 gattagttga aaacatataa tcttatctcg tttgcttgtt ttcaagtcta acataacata
    39061 aaatatatat cctctcattt gatgctccat tttgtaaagc tattatttaa gctttacttt
    39121 agatttttta gcaaattgaa ataaagcaat ttataaaata agtatttaca aattaagtgt
    39181 attaatcgta taatacactt aataggatac tagataaagt ctgaaataaa ggcgtatttt
    39241 tttaaagtaa gtgtactatc gtattaatac actagaatag gaggaatcat gaattttgaa
    39301 ttagataata caactcccat ttatttgcaa atagtaaagt atataaagag acaaatagta
    39361 acaggagagt tgaaaccagg agagacaata ccatcaagaa gagaaatggc acttaatcta
    39421 aaagtaaact taaatacagt tcaaagagca tataaggaga tgggtgatat gaatataata
    39481 aatactttta aaaattatca aagcagtgta acagttgatg aaaatatatt aaaaaattta
    39541 aaattagagc ttataaatga atcactatct gtttttatag aagatatgaa agcaataaat
    39601 gttagcaaag aagaagtttt aaaaataata gaagataagt attagttttt taacaaatag
    39661 aaaacttagt ttagaaagtt tatttataag catattggat gtggaggata gtaaatatga
    39721 tagaaataaa gaatgtcagc aaaacatata aaaggatgca agggcttaaa ataagaaaga
    39781 tagaagcttt aaaaaatgta agttttaata tagaaaaggg aaaaataact gcattacttg
    39841 gtataaatgg tgttggtaaa tcaactatgt taaaagcaat agcaggactt ataaacattg
    39901 atagtggaga aattcgtata gatggagaaa aaataaatga aaaggtatac aataaattgg
    39961 cttttgttcc agatgtacaa tctcacttta gcaatacaac aataaaagaa acatttgaat
    40021 ttatggaaat tttttattca aagtggaata aagaaaaatc aaaagaaatg atggacatat
    40081 ttaaattgga tgaagatgaa ataattgata acttgtcaaa aggaaacatt gcaagagtaa
    40141 aattaatact tggattttgc caagacccag agtacatact tcttgatgaa ccatttacag
    40201 gaattgattt gtttaagagg gaagagttta taggagtaat agcgcaatat atggaggaaa
    40261 atcaagccat tatcataact actcatgaga tagtagagat agaaagttta gttgatgagg
    40321 ttgtaattct tgatgaaggg cagattataa cttcatttaa tgcagaagaa ttaagagaaa
    40381 gagaaggtaa atctatatta gataagatga gggaggtata taagaatgaa taaacttcta
    40441 tatctaataa atgtagattt gagaagaagc aataagtttt atatagctta tatatcattt
    40501 ttttcattaa ttacacttag tttaaattta ttcgaaatta ataaatttaa aaattctaaa
    40561 tttattatga acttagcaat agaagatttt ggaggtatat tttatggact agggatactt
    40621 agtaatcttg gttttatcca aaatatattg ttctttggaa tgttgggact ttttatatac
    40681 tatattttta tgtggaaaag agagttcttt tcaaataatc aaagtattta tacacttatg
    40741 atgttacctc aaaataagtt taagatttgt atatctaaat caatagtttt gataacaatg
    40801 atatatggtt ttttgataag tcagacagca acattattta tatgtaaata tatatttaat
    40861 ttcattttta gaaatattcc tataatcaat atgaactttg ccaaagattt atattattta
    40921 aacttgaaga gtataccaat tgattttatc tcttttatgg ctatttatgt atttttacta
    40981 cttatagcta tttctattgt aaattgctgt atattattta tcttttccta tataaataaa
    41041 ttttatgtaa ttttaatcac tttgctgatt atagcaggct tatatttttc aacaatatat
    41101 ataaatataa tcaatttatt tagaaaatat tataatctta taggatttca atttaacaat
    41161 ttagtagcag ggttattaag ttttttaatt ataatgttta ttctaaatgg aatatcttat
    41221 ttgctaatta aaaagaaagt atctctttaa ggaggggtgg tatgaaatta aaatctaaaa
    41281 tatctatact tattatattt ttgactttag caatatattt tagtataggt ttattaaata
    41341 atgaagataa tttaaagata aaaactataa aaggtgactc taatgaatta gaccatataa
    41401 acataaattt tggatatgct ttgaatggat atataaattc atattataca ataaatggaa
    41461 gtaacaaaac taaaaagact gaattaataa aactacaaaa ggatagtaag aacacaaata
    41521 atttaattga tgtatctagt ggttcagatt taattgctca tgttggattt gaaatgaatg
    41581 aggagtcaaa agatataaac tttgtgatag atgagaaaaa agaagattta gaaaaaggtg
    41641 tatttccatc agaaggtagt gataaagaaa ttgaatatga aaaattagat atgaataatt
    41701 ttacaaggac aagatataaa gtagataaaa gtacagatga ttattatgca aatatactag
    41761 catcaaaaag atataaaaaa tacttatatg tatctgtact ttatgctaca agtgattcat
    41821 cagaaaataa caaagaatat tcaagtacta tagatataat aaaaattaat ccagaaaata
    41881 aaaaaatcaa gactataaaa agtataaatt taagtaatta tttttccgag aaataccaag
    41941 acatagagaa cataggtgta agttatgcta gcaaatatga ggataagatg tatattttag
    42001 taaatgtact aaatacaaac ataggtgata atagtaattc taaatttcat ttacttgagt
    42061 ataatcttga agaaaataag gaaagcataa tggaattaaa aactgatagc aaaatggctt
    42121 tagcaaaagc aaagttagaa gctaataaat tatatatggt aatgtcgaat gattatgata
    42181 atagttcaat tacagagtta aatttactta cctataatat attagataaa agcttagatg
    42241 aagataaata tgttttagat aatagagaaa aaagaggaat tagaagtatt gaaattgatt
    42301 caaataaaat cgttgcatat acatcaaggc taaactctat attatcttgg gataataaat
    42361 ttatgctata tataataaat aaaaattcta aggaaattgt atatgaagga gaattacaat
    42421 ttaacagttc aaatagtatg ttagaatttg aaataaagta ggtgagttga tgaaagattt
    42481 aataagatta ttcgaatttg aattaaaaag aaatataaag aattatatat ttataataat
    42541 ttgttgttgt tcttttgtaa ttttaaacat agtaaaaaat ttaaatgact ataattacat
    42601 aatagaaaat gcagttaaaa gtgaacagtt aacaaaaatc ggaaatacga tagaaacggt
    42661 aaatgttaca ggtttctcaa gctttagaaa tataatgggt tctacagaat cgtggtttat
    42721 atttggtata attgcatgta tttgctatgc tttttttatt tggtatagag actttaatgg
    42781 taggagtaaa tctatatata cacttataat gctacctaaa aatagaatca atatttatat
    42841 atctaaatta ttaaatatat tatttctagt gtatagctat acagtagtac ttacaatatc
    42901 tttgtttatt gcaagtaagt tgttgcctag acatatgctt ggtaatgtca caaactatgg
    42961 ttttgtacaa gaaacaatat atgagttaaa aatgttactt ccatatagct ttgaaatact
    43021 atttgtagag tatatatttt tattgatagg atttgtatct gtagtattta catcaattct
    43081 tataaataaa tctatttata aagtaagcac tttaataagt tttctatttt tagttttgga
    43141 aattttagtg tttataattt ctatagaatt tattatacct tatgaataca gtgatgtatt
    43201 tactgttcta tattcaagta taaacatatt tgtatgtagt cttatatcta ataaactttt
    43261 gaagcaaaag attgactttt aggagggata ttatgaaagc aaaaaatata ggaaaatata
    43321 caatatgttt tataatagta tgttttttaa tgattactat gaccttaata ttgagttatt
    43381 ttaataagga taaactatct gtaaaaactt taaaaggcaa tgtaaaagat atagggagag
    43441 taagtgtagt atatacacct aatataagca aattttctta tgaggaggta attataagta
    43501 aaaatggagt aagaaataat aaaaacccca aatcaagaat tagaaatgat tatttaaata
    43561 ttgacaaaaa atacagtgat tttgttaatg ataaaggaaa agaacttata tataaagatg
    43621 atttgaatat aggagaagcg tatacctctg ttaagtctga tttagtacaa ggaatgaatg
    43681 ctttaaatga ttgtataaag gtttcaaata aaaatttaaa aagtggggta gaagaaaatt
    43741 ttgatattaa tttaaataag tctgatttta aagaaaacag ttggaaaacc ttgtttaata
    43801 aaatatataa aggcaattta tatatggtaa ttagtgaaac taatatttca ggttctaagg
    43861 tcaataatat ttgtatatta aagatagata taaaaaataa gtcttataaa ttattaaata
    43921 gatttaattt aggattacag aatggatatc aacaaaatat caatgaaatt aaattttcta
    43981 ttggaagtaa attatactta gaaatagtaa ataataaaag taaaaatgga gatattgaag
    44041 gacatgatag ttactctaac cttattatat atgatataga agataacact tttaatataa
    44101 gtaataaatt tatggataat ctaaacaaag aaaagaatgc aaatccaaag gagattggct
    44161 tattaagtaa aactaagcta gattatatga taaaaaataa taaattgaat cttatagtta
    44221 cggatatgag taattccata atcaatcttg tttatgatat taattctaat gagattaaat
    44281 tagaagatta tgagatactt gatttaaaag tagattataa tgaagcatca tctggagtta
    44341 ggaaagttaa gttactggat gataagattt attctatttc aggtatgaag aacagtatat
    44401 caggagaatt aaaaggattt aaagggattg ttgatgtagt cggaactaag ccagtaaaat
    44461 ttcaagtatt tgatatgaaa cttaaaaaga atatttatga agctgagcta ataaatggag
    44521 atataagttt acaagaaaag ttattttttg ttgcaaatta agtattagaa ttaattttag
    44581 aactttaaac ttttatatgt atcacagata agtataagta agggagtgtc tcaaaataaa
    44641 ctttttagtt catgagacac tttttttata tgaaatcaaa tatattttca ttgtttagat
    44701 ttattttgat aatgaaaaaa agattatctt tattttaaga aagacattta tttataatta
    44761 tatacaaaaa tattttttaa tgtttttgtg tataattata acaatttaat ttatattaat
    44821 gcacttaaat ttgaaataga atgcttatag tggtaaaatt aattattaga atattagaaa
    44881 taataaataa ataatacatt gtacttaaaa gggggagaaa tttaagatga acaaaaaata
    44941 tattaaagca gggaatttaa ttgatggaac aggaaatagt attatgcaaa ataagggtat
    45001 aattattgat ggagatacta tagttgaaat tgaagatata agagatgatt taaatggata
    45061 tgatgtgtac gattacttag ataaaactgt tatgccaggc attatgaatt gtcatgttca
    45121 cttgacaatg gagccagttg gaaatccaaa gatatattat gataatgtat cagatgtaga
    45181 gcttgtagta aatacgataa aacaagttga tgcttatttg gattcaggag taacatatat
    45241 tagaagctta ggttgtccca aatatgtgga tgtacaactt aaaaatctta tagacaaagg
    45301 gtctatagat ggtcctggta tagttacttc aggtccagtt atatgtatga caggagggca
    45361 tggatattat tttggtattg aaagtgatgg agtggatgaa tgtagaaaat cagccagaac
    45421 agttttaaaa aatggagtag attgtgtaaa gataatggca actggaggtg taacaactga
    45481 tggagttgag ccagggtcac cacaattaac tttggaggaa atgaaggctg ctgtagatga
    45541 agctataaaa gcaggtaaaa taactgccac acatgcacaa ggaagaactg gtataaaaaa
    45601 tgcagttctt gcaggaatta cttctataga acatggtgtt tatttagatg atgaaataat
    45661 tgatttgatg cttgaaagag gaacttactt agttccaact gtggctgcac catattttat
    45721 tctaaatgca ggaaaagaaa gtggaataac tgaagctact cttagaaagt gtgagattgt
    45781 tgccattcca cataaagaat cattcctaaa agcatataaa aaaggaatta aaattgcagt
    45841 tggttctgat gcaggaactt cttataatga acatggaaaa acatattatg aaatgaagct
    45901 aatgtcagat tatggtatgg ataatatgga tataatagtt gctgctacaa aaacagcatc
    45961 tgaactttta agaattgata aaaattatgg aactctagaa aaaggaaaga aagcagatgt
    46021 tatagttgta aatggaaatc cagtagagaa tatagacgta cttgcagatg tgttagcagt
    46081 atttaaactt ggtaaaaaag ttagataaat agtataaaaa taaaaaagag tgtctaaaga
    46141 aatttttaaa taattataga cactcttttt tattagtaat aattaaatct tttatacttt
    46201 agaaaataga ttctatttta tatttagata taactcttta aaatcattct tatgcaatat
    46261 aatctataga atctacacat acaaagtata ttcttgaatc attagaattt ccaagtacta
    46321 taacatcatt tttcttacct agaacttcaa caccagttag aaccaaacta ccagctacta
    46381 cagtaacttg attatttata tttgacatat aaagattatc taggatacct ttattacaac
    46441 agcaatcatc acaatcgcag ttacaattac attctttgta atgtttttta tcaagatagt
    46501 aacctaaaga tgctatgaaa tcttcataat ctgcaggtgt aatatcaaat gcaacagctt
    46561 taagattaca caatgatgct aaatctacgt ttgctaatgg agtagatgca gcaagtataa
    46621 aatcaattat agcagcaagt attgcatcta atatagcccc aaggtctatc gtaggaggaa
    46681 taactgcatc aataagtgca attaattcag ctactcctgg tatagttcct atagtattaa
    46741 ttaatccctc aagagttaaa gggactggaa taggataaga tactctacca gctatatcta
    46801 ttaaatcaca gttacaagca gaaaatcttt caaaagtacc atcaagtcca gataaattat
    46861 cttttggagg agctgaaaga tctataccta ccaaattagc acctactata aagaaatctg
    46921 agataaaagc aaattgatta aagtttacaa aaggtcttag agcatcatat cttagaagtt
    46981 ctaaggcctc tctcatactt tttttacaac aacattgttt tattttaggt tctttatatt
    47041 tatttggata attatagtat ctatcagcta cttgataatt ttcatagtat ctttcatttg
    47101 tatttggata atcttcctca tattcttgtg taaatctaaa gtcctctcta catttattat
    47161 tttccactaa atacactcct tttatatttt aatttaaatg tatagataa
//
LOCUS       DAMJYN010000025        46104 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.025, whole genome shotgun sequence.
ACCESSION   DAMJYN010000025 DAMJYN010000000
VERSION     DAMJYN010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 46104)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46104)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46104
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.025"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            127..1008
                     /locus_tag="PC466_001496"
     CDS             127..1008
                     /locus_tag="PC466_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HDF2768886.1"
                     /translation="MKKRLIIMILSVVLVLSSILTIFAYSNIKYNNNKLIYSNMIDKK
                     TQNSVKEILKENKINEKDIDTFIKAVNNYNKLQVKILQNNINISKSGYSSINAKQVPY
                     NLEKLQDNWVKKFPDYMDVNCRITAFRLFKDFINSNKKFTGDSIDLNVDLDTIMNNKD
                     AKFSTKDVEKFINFFSAIPAKDTDDTIKIAEQIKNEWKKRKISFKNNKNISIINGFLR
                     YPETKNVFIGHTGICIKTKNGILFLEKYGVTSPYQVTKFKNKKGVKNYMFNRLKMSEG
                     EIELPDPIIMENDKLMK"
     gene            complement(1321..2100)
                     /gene="hisJ"
                     /locus_tag="PC466_001497"
     CDS             complement(1321..2100)
                     /gene="hisJ"
                     /locus_tag="PC466_001497"
                     /EC_number="3.1.3.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase HisJ"
                     /protein_id="HDF2768887.1"
                     /translation="MKDGHIHSPYCPHGSKDDFEKYVQRAMDVGITEMTFTEHFPYAN
                     GFRDPAPENDSCMSIEDLPKYFNDVKKLKEKYEGKIKINVGSEVDFIEGYEEGIKENL
                     NKYGKELEDSLLSVHIIKIDDDYYCVDYSVEEFQNLIDKLGSIEAVYNKYYETLIKAV
                     NSDLGIHKPKRIGHLNLVRKFNQVFPYDYKGNTILEDLIKLIKEKGYELDYNVSGNRK
                     EYCKEPYIDGYLLELVKKYDIPLVLGSDSHCAEEINKYDII"
     gene            complement(2640..2990)
                     /locus_tag="PC466_001498"
     CDS             complement(2640..2990)
                     /locus_tag="PC466_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc transporter"
                     /protein_id="HDF2768888.1"
                     /translation="MIFDKEIVRYHHGHHDHDHCHEHTHGDICHEHPHDHAHDHDHEH
                     SHEESSESKDEKTLKILLVHWINHNETHEEGFREWVEKARAIGKEETAKSIEKAIEYM
                     EEANKMLLEAKKHM"
     gene            complement(3006..3422)
                     /locus_tag="PC466_001499"
     CDS             complement(3006..3422)
                     /locus_tag="PC466_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3842 family protein"
                     /protein_id="HDF2768889.1"
                     /translation="MIIAVIDGMGGGIGAQIVSSLREELPTYVEIYALGTNSIATSSM
                     MKAHANKGATGENAIVVSAKKANIIVAPISVIIPNSMMGEVTCNISEAIADSEALKIL
                     LPIMPENVELVGLEGKPLALLVKDSVNLIKKEFNIK"
     gene            complement(3441..3632)
                     /locus_tag="PC466_001500"
     CDS             complement(3441..3632)
                     /locus_tag="PC466_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CooT family nickel-binding protein"
                     /protein_id="HDF2768890.1"
                     /translation="MCESSAFICKSNNELEKVMENVVNIDPCDGKIYLTDLLGEQKII
                     DGIIKEIRLMDHKIIIQEN"
     gene            complement(3783..4598)
                     /locus_tag="PC466_001501"
     CDS             complement(3783..4598)
                     /locus_tag="PC466_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HDF2768891.1"
                     /translation="MNQWRVIHNKSYEGAMNMAIDEAIFTAYKKGHNKPTLRFYTWEP
                     ACLSIGYFQKLEDEIDLDKCRCMNIDYTRRITGGRAVLHDNELTYSIIIGEDNPLIDK
                     SINLSYRYISEGLVKGLNLSGIETDNLNRGERISRENLSAACFNAHASYEVTINNKKV
                     IGSAQSRKDGVLLQHGSIILDFDVEKLFKLIKTKTPELKERAMKFTAKKASGIENEIG
                     RKIDIDILQKNIVKGLAEQFNVEFVEGDLTDYEKQLVKELYEKYKNEEYNKKR"
     gene            complement(4645..5583)
                     /locus_tag="PC466_001502"
     CDS             complement(4645..5583)
                     /locus_tag="PC466_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HDF2768892.1"
                     /translation="MIRLSVGTAIELGILNKKSDIPPTTAYIMIGEKCINKCSFCSQS
                     IESSTRKDKLSRVIWPEFSKEEILDALKAYKGKNIKRICIQSMASEEAHNSVLDFINY
                     ISGKIDMPISLSAKLENDEQIKKFFSVGVDKIGIAIDASNKELYEKIKGNNYDEKLKF
                     ITEMSKSYPNKISTHIIVGMGESHEDIYNLYIYLKENDVTISLFAFTPVRGTKMEKIN
                     QPSIESYRRVQLMSYMINKGYPKEYFKFKNGYLNSIKLDNDILKDINKGYPFEIRGCK
                     DCNRPYYNERPGSTIYNYSRPLNQSEIDLAIREINL"
     gene            complement(5580..6452)
                     /locus_tag="PC466_001503"
     CDS             complement(5580..6452)
                     /locus_tag="PC466_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HDF2768893.1"
                     /translation="MNKNLSEKMKIAFDIKLKNFGNKIEFAYPNQTLALSTTSNQCSL
                     KCAHCNGHYLNNMVPIEEYEEKVQSRNITSFLLSGGCSYEGDVPINTHINTIKNLKEK
                     GYRLNAHLGLMDKDSIVELCKYLDIVSFDLVFDDETIREVYKMKKSKEDYIEVYNTIQ
                     EHTEVAPHICIGLKGGQIKGEYEIIEYLQKNPPNKLTFIVLIPTKGTEYENVEPPELE
                     GVADILCEARINLPDTEINLGCMRPRGVYRKELDQLSIMCGVNRIVLPSRSAKNKAIE
                     MNMTINECKECCVL"
     gene            complement(6477..8405)
                     /locus_tag="PC466_001504"
     CDS             complement(6477..8405)
                     /locus_tag="PC466_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4445 domain-containing protein"
                     /protein_id="HDF2768894.1"
                     /translation="MIKVSFTPNNKEVYCNEGDILLEVARNADIFIDAPCNGNVSCGK
                     CKVKLLNGKVDTEKTRHITDDEWEQGYILACCTKVISDIEIEVPSKVSSSMHGMKIEG
                     SNKKEDREIFERAKKIIEEHNLQFKTNIKKKYIEMEEPNLDDNISDVDRLERYVRNSL
                     GYNEIDFRLDILRKMPTVFRKSDFKVTITYVQKQKKLTIINIEQGNKENSLYGVAIDI
                     GTTSVVVCLVDLYSKEVVDKASSGNAQIKYGADVINRIIYSTKKNGLETLHKAIVEET
                     INPLLKTIYERNGIDKEDVVTLVAAGNTTMTSLFLGVYTDFLRQEPYIPPFLKSPKLM
                     GENVGLFVNDSAYVYLAPSVASYVGGDITAGVLSAGIWSSEENVLFIDLGTNGEIVFG
                     NKDYMMSCACSAGPAFEGGGISCGMRASAGAIEKVIIDKETLEPTLKIIDECAPVGIC
                     GSGIIDLICQMITKGVIDRRGKIYRDLDNKRVRFNEHEIGEYVLAFKEEFDLENDIVV
                     NEVDIDNFIRAKGAIYSGAYTLVDSLGMDFSILDRVYIAGGIGNNLDIENSIIIGLLP
                     DIDREKFTYIGNSSLVGSYLALISKDAKNKLEEIGNQITYVELSVYPSYMDEFISACF
                     LPHTNIEQFPTAKKLLEE"
     gene            complement(8517..8894)
                     /gene="gcvH"
                     /locus_tag="PC466_001505"
     CDS             complement(8517..8894)
                     /gene="gcvH"
                     /locus_tag="PC466_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein GcvH"
                     /protein_id="HDF2768895.1"
                     /translation="MKLLPELKYSKDHEWVKVIDGDVVYIGITDYAQDQLGEILFVET
                     PEVEDTVTKGVDFGVVESSKVASDLISPVNGEVLEVNEKLEDEPECINEDPYENWILK
                     VKLADVAELDTLLSDKEYEAGLE"
     gene            complement(8981..11107)
                     /gene="cdhC"
                     /locus_tag="PC466_001506"
     CDS             complement(8981..11107)
                     /gene="cdhC"
                     /locus_tag="PC466_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CO dehydrogenase/CO-methylating acetyl-CoA
                     synthase complex subunit beta"
                     /protein_id="HDF2768896.1"
                     /translation="MNLYNIIFTGSEQALGAAQAMLAEAIEKNGKEHKVAFPDTAYSL
                     PCIYAATGQKMNTLGDLEGALEVVKSLINRTHLLEHAFNAGLATALAAEVIEALKYST
                     MDAPYSEPCAGHITDPIIRSLGVPLVTGDIPGVAVVLGECPDAESAAKVIKDYQSKGL
                     LTFLVGKVIDQAIEAGVKMGLELRVIPLGYDVTSVIHVVSVAVRAALIFGGLTPGDLN
                     GLLEYTANRVPAFVNAFGPLSELVVSAGAGAIALGFPVITDQTVLEVPMNLLTQKDYD
                     KIVATSLEARGIKIKVTEIPIPVSFAAAFEGERIRKSDMFAEFGGNRTEAWELVVKKE
                     ATEVEDHKIEIIGPNIDEVDADGVLRLPLAVIVKIAGKNMQEDFEPVLERRFHYFLNY
                     IEGVMHVGQRDMAWVRISKDAFDKGFRLEHIGEVLYAKMLDEFESVVDKCEITIITDA
                     EKVSELKGEAIAKYNARDERLASLVDESVDTFYSCNLCQSFAPAHVCVVTPERLGLCG
                     AVSWLDAKATKELDPTGPCQPIEKGECLDDRTGVWNSVNETVNQISQGAVESVTLYSI
                     LEDPMTSCGCFECICGIMPEANGFVVVNREFASVTPVGMTFGELASMTGGGVQTPGFM
                     GHGRHFISSKKFAYAEGGPERIVWMPKELKDYVADKLNATVKEMTGIENFCDMVCDET
                     IADDSEGVLAFLEEKGHPALAMESVM"
     gene            complement(11164..11970)
                     /locus_tag="PC466_001507"
     CDS             complement(11164..11970)
                     /locus_tag="PC466_001507"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HDF2768897.1"
                     /translation="MEKFMIIGERIHCISPSIRKALAERDPAPILKRAKEQLEAGAHY
                     IDFNIGPAERDGEEIMTWGIKLLQSEFNNVPIALDTANKKAIEAGLKVYDRTNAKPII
                     NSADAGSRFDLIDIAAEYEAMVIGLCAKEGIPRDNDERMAYCQEILEKGLMLGMEPTD
                     ILFDPLCLVIKGMQEKQVEVLEAIKMMTEMGLLTTGGLSNVSNGCPKHVRPVLDSAFL
                     AMAMANGFSSAIMNPCDPELMKTVKSCDIINGASLYADSFLELNEGGFAF"
     gene            complement(12020..13387)
                     /locus_tag="PC466_001508"
     CDS             complement(12020..13387)
                     /locus_tag="PC466_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA decarbonylase/synthase complex
                     subunit gamma"
                     /protein_id="HDF2768898.1"
                     /translation="MALKALDIFKLTPKKNCKDCGFPTCMAFSMKVASGAVEVGKCPH
                     MSDDAIAKLSEATAPLMKALKVGAGASEYELGGETVLFRHEKTLVSRNRYAVSFCTCM
                     SDEAVDAKIANMKKVDYVRIGEQMKVEMAVLEYCGDKDAYLKLIDKIKGSGLEVAYIL
                     ACDDAQVVKEAVEVLKDARPMVYGATKENYKDMIEVVKGASLPLGVKAGSLEELYETV
                     ELIQAAGYKELVLDVTGENIKDTYTNAIQVRRTALKEQDRTFGYPSIVFANRLSNSNP
                     MMEVALSSIFTIKYGSIIVIDDISYAKALPLFALRQNIYTDPQRPMRVEPKIYPINNP
                     DENSPVLVTVDFALTYFIVAGDIERSKVPVWLVIPDAGGYSVLTSWAAGKFGGNSISA
                     FIKESKVEEVTNCKDLIIPGKVAVLKGDIEDNLPGWNVVIGPEESMELPKFLKGYQEK
                     ACQTN"
     gene            complement(13418..14362)
                     /locus_tag="PC466_001509"
     CDS             complement(13418..14362)
                     /locus_tag="PC466_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA decarbonylase/synthase complex
                     subunit delta"
                     /protein_id="HDF2768899.1"
                     /translation="MAFKMSTQKYSGKISEVEVGIGEKAIKLGGENVLPFYSFDGEVG
                     NSPKIGIQISDVYPESWTDSYKELYKDVANCPVEWAKYVEANTQADFICLKFDGSDPN
                     GLDKSVDECADVAKAVIEAIKLPLVVAGSGNHEKDGKLFEKLAQTLDGHNCLFMSAVE
                     DNYKGVGASAGMAYAHKVGAESSVDINLAKQLNVLLTQLGVKGENIVMNVGCSAVGYG
                     YEYVASTMDRIRLAAFGQNDKTLQMPIITPVAFEVGHVKEAIAPIEDEPDWGCPEERT
                     IAMEVSTAASVLVGGSNAVILRHPKSIETIKELVNALA"
     gene            complement(14382..15152)
                     /locus_tag="PC466_001510"
     CDS             complement(14382..15152)
                     /locus_tag="PC466_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF2768900.1"
                     /translation="MGYNIAVAGKGGTGKTSLTGLLIDYLVKDKKGPVLVVDADANAN
                     INEVLGIEVEATIGEIREEVNQREKLGNAFPGGMTKAQYLQFRLNSIIEEGEGYDLLV
                     MGRSEGEGCYCFVNGILREQVNKISGHYKYLVMDNEAGMEHLSRKVTRHVDTLLLVSD
                     CSRRSIQAVARIRDLAEELKLSVGRILLIVNKVPNGVMNDGVKEEIEKHNLELIGVVP
                     MDELIYEYDSTGIPLVNLPEDSKSKVAMKEIFAKLELK"
     gene            complement(15208..16593)
                     /gene="lpdA"
                     /locus_tag="PC466_001511"
     CDS             complement(15208..16593)
                     /gene="lpdA"
                     /locus_tag="PC466_001511"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HDF2768901.1"
                     /translation="MKIVVVGGGPGGYVAAIKASMLGADVTVIEKRRVGGTCLNAGCI
                     PTKALLASSGVLNTVKEAKDFGIEIDGTVKPNFTAIMERKNKVVNQLISGIEFLFEKR
                     GVNLVNGFGKLIDKNTIEVTKDDGTVETIKADKIILANGSVPVVPRMFPYDGKVVITS
                     DEVLGLEEIPESMLIVGGGVIGCEIGQFFRALGTEVTIVEMVDQILLNEDKDVAKQLL
                     RQFKKDKIKVITGIGVQTCEVVDGKAVATLSNGKVIEAQYALVCVGRRPNLDNSGVED
                     IGIEMERGKVVVNEHLETNVEGIYAIGDIIDTPFLAHVASKEGIVAVENALGKTKVVD
                     YRAIPRCVYTEPEVAGVGKTEKQLEAEGVEYNVGQFDFRGLGKAQAIGHFQGFVKVIA
                     DKETDKIIGAAVVGPHATDLLTELSLAVHLGLTVEQVGDAIHPHPSLSEGLMEALHDV
                     HGECVHSVPKL"
     gene            complement(16637..17518)
                     /locus_tag="PC466_001512"
     CDS             complement(16637..17518)
                     /locus_tag="PC466_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase"
                     /protein_id="HDF2768902.1"
                     /translation="MSLLRETLESGKFAVTTEMAPPKGTDLSHLIECAKPLVGRVHAA
                     NVTDFQSAVMRATSLATCKLLKDAGLEPVIQITGRDRNRIAIQGEMLSAGVFGINNLL
                     ALTGDHTSVGDHPQAKGVFDLDSVGILQTAETLMAGTDMAGNKLKGSPDFYLGASVTP
                     EYSPIEVQLLKMQKKIKAGAKFFQTQALYDINTMRKFRELTRDMDCKVLAGIVPLKSP
                     GMAKFMTANVPGIFVPDEQIERLRAAGKENWVSEGIKMAGELIKQLKEEDLCDGVHIM
                     AIGAEENIPAILDAAGL"
     gene            complement(17554..18228)
                     /locus_tag="PC466_001513"
     CDS             complement(17554..18228)
                     /locus_tag="PC466_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase C-terminal
                     domain-containing protein"
                     /protein_id="HDF2768903.1"
                     /translation="MIISENKPLEEVLGYLKDFDKLVLVGCNQCAATCKSGGEEEVLK
                     MKETLEGEGKKILGYVMLDPACNLLKSKKDLKALKEETKEADAVLSLACGDGTQTIVK
                     NLKDKPVYPANNTLFIGEVQRVGEYEEACKACGDCELGWTGGICPVTMCAKGLMNGAC
                     GGAKNGKCEVNSENDCAWIKIYERLEAIGQLDNLAEIRPPKDYSKQNNPRSLSAKKKK
                     EAAANS"
     gene            complement(18265..19137)
                     /locus_tag="PC466_001514"
     CDS             complement(18265..19137)
                     /locus_tag="PC466_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 5,10-methylene-tetrahydrofolate
                     dehydrogenase/5,10-methylene-tetrahydrofolate
                     cyclohydrolase"
                     /protein_id="HDF2768904.1"
                     /translation="MEGMSTKGQIIKGKPVADKISEELIKEVDLLVKEGINPKLTIVR
                     VGARSDDLSYERGALKRCQNIGITTEVLELAEDITQEEYIDVLKRVNDDKNVNGILCF
                     RPLPKHLNEEVIKYVIAPEKDVDCFSPINSAKVMEGDKSGFPPCTPTAVVEILKHYNV
                     DLKGSKVTVLGRSMVVGKPVSMLLLSEHATVTICHSKTKNLSGVAAEADVLIAAIGRA
                     KMVDESFVKDGAVVIDVGINVDEEGNLCGDVDTNAVLDKVSMITPVPAGVGSVTTSIL
                     AKHVVKACKLQNNK"
     gene            complement(19229..19861)
                     /locus_tag="PC466_001515"
     CDS             complement(19229..19861)
                     /locus_tag="PC466_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclodeaminase/cyclohydrolase family protein"
                     /protein_id="HDF2768905.1"
                     /translation="MKIADKTCVDFVEVLSSKEAVPGGGGAAALVGAIGMALGSMVCN
                     LTIGKKKYAEYEESVKEILSKAGKLEKDLLKMIDDDAECFLPLSKAYGLPKETEEEKR
                     IKAETMEKALKVACEVPLNIVRVCYEAIKLHEDLVDKGSRLAISDVGVGVQCLRAAIL
                     GGQLNVVININSIQDKEYVNKVKIEVDKLVEDGVKICDEVYAKVEKALGK"
     gene            complement(19966..21642)
                     /locus_tag="PC466_001516"
     CDS             complement(19966..21642)
                     /locus_tag="PC466_001516"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014355320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HDF2768906.1"
                     /translation="MGFKSDIEIAQEAKPQDIREVAKKLGLGEDDVELYGKYKAKVDY
                     NLLKRETGKKAKLILTTAINPTPAGEGKTTTTIGVADAFAKLDKNVLVALREPSLGPV
                     FGVKGGAAGGGYAQVVPMEDINLHFTGDFHAIGAANNLLAAMLDNHIHQGNALRIDPK
                     KITWRRCVDMNDRQLRNIVDGMGKKGDGAVRQDGFDITVASEIMAAFCLASDISDLKE
                     RLGNIIVGYSYEGEPVTARQLKANGAMAALLKDALKPNLVQTLEGTPSFVHGGPFANI
                     AHGCNSVIATRMAMHFADYVITEAGFGADLGAEKFLDIKCRMANLKPDAVIIVATVRA
                     LKYNGGVAKADLNNENLEALEKGLPNLLKHVENITQVYGLPAVVAINRFPLDTEAELK
                     LVEDKCKELGVNVALSEVWAKGGEGGIAVAKEVLRLLDEEENNFRFCYEDDLSIKDKI
                     NAIATKIYGADGVDYTPEADKEIANLEKLGFTKVPVCMAKTQYSLTDDQTKLGRPTGF
                     RITVRQATISAGAGFIVALTGEIMKMPGLPKVPAAEKIDVDENGVIAGLF"
     gene            complement(21891..22670)
                     /locus_tag="PC466_001517"
     CDS             complement(21891..22670)
                     /locus_tag="PC466_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF2768907.1"
                     /translation="MKIAITGKGGVGKTTFSSMLSRMFAEDGYRVVAVDADPDANLAL
                     ALGFPKEVYESIVPISEMKKLVSDRTAASVGSFGKMFKMNPKVDDIPENFCKEYNGVR
                     LLTLGTVDSGGTGCVCPEHVLLKRLCSHLILQNKDVVVMDMEAGIEHLGRGTAQGVDA
                     FIVVVEPGERSLQTYRKVKKLGHDIGVNKVFVVGNKIRNKEDEEFIIQNLEDGESLGF
                     IYYNQDVIDSDRANQSPYDSSETTKEQIKAIKDKLMSLKDK"
     gene            complement(22980..24899)
                     /gene="cooS"
                     /locus_tag="PC466_001518"
     CDS             complement(22980..24899)
                     /gene="cooS"
                     /locus_tag="PC466_001518"
                     /EC_number="1.2.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic carbon-monoxide dehydrogenase
                     catalytic subunit"
                     /protein_id="HDF2768908.1"
                     /translation="MDEKMLTIDLNSQKMIAKAREEGVETMYDRKEGFKAQCGFGLQG
                     VCCRICGMGPCRISPKTPRGLCGADEHTIVGRNFARMVAGGTAAHSDHARDIAHTLAL
                     ADPNGNYKIRDEAKLITLAKEWDVETEGRDIYDVAHEVAEIALMEFGKPFGTLRFIKN
                     APEPRQKIWKEYAIEPRAIDREIATIMHSTHIGCTGDIDSLIHMSLRTSMADGWGGSM
                     IGTRLSDILFGTPVPRRTEANLAVLEENKVNIILHGHEPALSEMIVLASEEPDLVALA
                     KEVGADGINLAGMCCTGNEITMRHGVKIAGDFHQQELAIITGAVEAVIVDVQCIFPAL
                     ARVADCYHTKFVTTSPKAKITGSTYIEFREEQALDDAKAIVKEAILNFKNRDKSKVLI
                     PELKSGATVGYSVEAVVNQLDRVVNSHIDPAGTVKPLTDCLKAGVLRGAAGVVGCNNA
                     KGVSNEAHVTIMKELIKNDIIVVTTGCGASAAAKFGLMESDAAEKYAGKGLATVCKLV
                     GIPPVLHMGSCVDISRILDLVGAAANYLDMDMCDLPVVGIAPEWMSEKAVAIGCYVVA
                     SGIDTYLGIMPPIAGSSRAVDILTSELKDKVGATFTVNTNPKELAATIIEDIEKKRVH
                     FEALVEEKMAEKAEA"
     gene            complement(25506..26417)
                     /locus_tag="PC466_001519"
     CDS             complement(25506..26417)
                     /locus_tag="PC466_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional enoyl-CoA hydratase/phosphate
                     acetyltransferase"
                     /protein_id="HDF2768909.1"
                     /translation="MIKKLDDILEQLKGGEKIVLSVAAAHDKEVLMAIKDAVERNIIT
                     PILVGNEGKIREISKEIGFDLSGIKIVDKDDIKECAEIAVKLVSSKEADFVMKGLLDT
                     SVILKEVLNKDYGLRTDSLLSHVMVYELEKYHKLLITTDGGMNIAPDYEQKAKILKNS
                     IKAAKALGMETVKVACLAAKEKVNPKMQATVDADMLAKACKEGEFGENVIVEGPLAFD
                     LAVSKEASEIKGFKSEVSGDVDIILVPTIEVGNGIGKAFTYMADSKSAGIIMGAKAPI
                     VLVSRADSHESKLYSIAYGAIVAKNMK"
     gene            complement(26533..26655)
                     /locus_tag="PC466_001520"
                     /pseudo
     CDS             complement(26533..26655)
                     /locus_tag="PC466_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902116.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
     gene            complement(26738..27880)
                     /locus_tag="PC466_001521"
     CDS             complement(26738..27880)
                     /locus_tag="PC466_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HDF2768910.1"
                     /translation="MDFKIEKYLLKKAEELAFITIKHGGEFKLKSYKVPKGGLDVPIK
                     NEVLVKGIKEKTAQDKLNSMSIADAMIYIIGIDSKFKNNAEYEKFLNALSKDIDLDLK
                     SYMGYMSRKYFEIGEHTDSLIYIKAFITMYPDDLDAMYNYAIVCQEIAKQYQKDMDDK
                     AMNAFLLEAMAKLEKVIDVDENFALGYYHLGYHYYNQGQYLKTKLTWEEALRLGLDAD
                     LVAEVQENLGKMDFKVQYEEGYTLVFQGKFKEGLEKLLPLEEEHMDWWNLLFMIALGY
                     KGMGEIEQAKMYLEKILIIKPNQVDTIVELGLCEAYKNNLDKAIEYFEQAAKIKEDPE
                     ILCNLGMAYLNNGDIDDATYYIERAYELNPQDEITIACLRELGINK"
     gene            complement(27898..29652)
                     /locus_tag="PC466_001522"
     CDS             complement(27898..29652)
                     /locus_tag="PC466_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="B12-binding domain-containing radical SAM
                     protein"
                     /protein_id="HDF2768911.1"
                     /translation="MKILLTTLNSKFIHTNLAIRYLKEFVRDLIEVNMKEYTINNDLD
                     YILKDIYKNEYDIILFSTYIWNVGDIVKLCDNLKKIRPNTKIALGGPEVSYDSYEAMK
                     KYDFVDYILYGEGELIFRDLVLHLQGKMKINDVNGLVYRQGNEIIVNKPMELLQDLDE
                     IPSPYENLNPKEYENRIVYYESSRGCPFNCQYCLSSTIPGLRYFSLDRIKSDLKALID
                     ARVSQIKFIDRTFNANRKVAMEIMDFLMKNDNGYTTYHFEVTAYLIDDKMLEFLADCK
                     EGLFQFEIGVQSTNEKTLDAVGRRDDFKKLSHVVQTVASYRNIHQHLDLIAGLPYEDY
                     KSFENSFNDVFNLGIEHLQLGFLKMIKGTGMRKVADEHGFKYKDYAPYEFLYNNYISY
                     EETLKLKDIEDILERYYNSKNFVLSMRYIIGRFYKQSPFKFFEVFAKYFDENGYFDLA
                     QGKNQLYKILMDFYNEKINIDNDVFNDILKYDYISLGKTSNIPQFFNKLDVDDFKNRC
                     HVFLQDNDNLSTYLPSFVDKPAKHIIKYVHFEPFRFNVVDLKNDINTEIREVENVVLF
                     EYDDKKIFEKSKTHKVEI"
     gene            29788..29994
                     /locus_tag="PC466_001523"
     CDS             29788..29994
                     /locus_tag="PC466_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768912.1"
                     /translation="MELIEKVSINSLSKRDLLLIIKSLEYTNENTQISDFIDLRNNIV
                     KELCFLTDTKEKDFLDYLEKNSTL"
     gene            complement(29999..30922)
                     /locus_tag="PC466_001524"
     CDS             complement(29999..30922)
                     /locus_tag="PC466_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768913.1"
                     /translation="MNDELLKKVYTSSFSSASRALKDLTIINTKSLIDDKTQRCVYID
                     ENRLRDELIYYRFYGEKIGNINFLNILLPLILSNTNIQKSEDEVIKLIKKYVIYFKKE
                     ELLFDYLLGSVVYNSIMHNLINNSKIEYVELLQSIKDKIIGFSIELDKSDVVKFQMAR
                     IKAIQLIDKYIDLKSEDYDEESILLNVLNVLYDVYMEDRTVENEGINSIKKSILSILG
                     EDSKLNEDNIDFIFSMSEYVVKLRKYKIGVKAYNKSIDPRSLIRLEEGNTIIDPIFNQ
                     ITVMSKTFNDNILSIKINSKSGIYILKFKKV"
     gene            complement(31176..32876)
                     /locus_tag="PC466_001525"
     CDS             complement(31176..32876)
                     /locus_tag="PC466_001525"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HDF2768914.1"
                     /translation="MQDFKVAISNCLKEKIEDLSKEEIEALIEVPPNKDMGDYAFPCF
                     KLAKVFRKAPNMIASELAESIEPSGEITKVIQLGGYVNFFVNKSQLAETVIKKVLDEK
                     ENYGHSDFGKDKTVIVEYSSPNIAKPFHIGHIRTTVIGNALYKIYDSQGYKTIRINHL
                     GDYGTQFGKLIVAFKKWGEKEVVESNPIPELLKLYVRFHDEAEQHPEMEDEARAWFNK
                     LENGDEEAQELWQWFRNESLKEFNRVYKLLDIEFDSLAGESFYSDKMNRVIELLEEKN
                     LLKESKGARIVDLEEYKMPPALITKNDGSTLYMTRDLAAAIYRKETYDFDKCIYVVGS
                     QQNLHFQQWFKVIELMGYDWAKDLIHVGFGMVALEEGTMSTRKGRVVFLEDALNQAID
                     KTKEIILAKNPNAKNVDEISKQVGVGAVVFQELSNSRIKDYTFSWERTLSFDGETGPY
                     VQYTHARCCAVLRKAEVEVTSDIDYSLLADEDSAEVLRVIESFNKNILLALKKNEPHI
                     VTRFMLDLAQAFNKFYHDNPILVENLEIRKARLALVLATKQTLENSLKLLGMHAPERM
                     "
     gene            complement(33287..33700)
                     /locus_tag="PC466_001526"
     CDS             complement(33287..33700)
                     /locus_tag="PC466_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HDF2768915.1"
                     /translation="MILVSACLIGINCKYSGDNNENEKVKEYLKGKEFTLVCPEQLGG
                     LSTPRPPAEIVDGKVITKDNKDVTENFVRGANETLKIANLYVCSEAILKEGSPSCGCN
                     LIYDGSFSGKKIPGKGITARLLEEEGIKIKSEKDL"
     gene            complement(33768..36146)
                     /locus_tag="PC466_001527"
     CDS             complement(33768..36146)
                     /locus_tag="PC466_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HDF2768916.1"
                     /translation="MNEKSLRVLEYNKIIDLLKKKASSSLGLKYIENLVPNTDFVEVK
                     SMLEETSEAQSIIIKRGSVGLEGIHDIEDKVKRAYIGASLDPGSLIMIADTLRVARRL
                     RNSLSSSDEEDFNYPIIQSLSNSLYVYKDIEDQIYNAIISEVEISDNASSTLRDIRRR
                     IAQKNQSIRSKLNSIISSTTYQKYLQDAIISLRGDRFVVPVKSEYRSQVAGIVHDQSS
                     SGATLFIEPMTIVEMNNELRQLKLGEQEEIERILSEISAMVGEVSEDLISNQEILGRL
                     DFAFSKGKLSIQMRGIEPTLNEDKYLNIKNGRHPLLDKKKVVANTIYLGRDFHTLVIT
                     GPNTGGKTVTIKTVGLFALMTQSGLHIPADYGSSMCVYDNVFADIGDEQSIEQSLSTF
                     SSHMTNIVSILQNVTADSLVIFDELGAGTDPVEGAALAIAVLEDINSVGAKCIATTHY
                     SELKNYALTKPGVENAAVEFDIETLSPTYKLLIGVPGKSNAFEISRKLGLSDYVISRA
                     KEYINTENIALEDVLQNVEKNRIKAVEDREEAERLKEEIEKLKVEYDEKLEKLVSQRD
                     KMIEKAKSEAFSIIRQAKEEVDIIIKELRNLEQERASKEKNRKIEELRKELTSSMGSL
                     QPTVKSMIVPKVSNKEIKDLKPGEEVKVITLNQNGSVVSVDKKRKEAVVQIGIMKMTL
                     PFKSLQKTRKDVSTNVTKSTRNIIRSKSGSVKNEVDLRGLNLEEAIMEVEKYLDDAYV
                     AGLESVTVIHGIGTGVLKAGLQDILRRNRHVKSQRGGQYGEGGAGVTIVKLK"
     gene            36463..37914
                     /locus_tag="PC466_001528"
     CDS             36463..37914
                     /locus_tag="PC466_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-histidine dipeptidase"
                     /protein_id="HDF2768917.1"
                     /translation="MGNVLEGLKPESVFKNFEKISQIPRGSGNEKGISDFLLSFGKNL
                     GLETIQDESLNIIIRKPATKGYENCPGVVLQGHMDMVCEKEKNVEHDFLKDPIKLRID
                     GDMIYATGTTLGADNGIAVAMGMAILEDNTLEHPALEVLVTVNEEDGMNGADALDPSL
                     IKGQYILNMDSEEEGYLLVSCAGGKTCVVSLPVEYKEVKGDKQGLLVEVTGLLGGHSG
                     MEIVLQRANANKAIARVLSVLNVDYELASVDGGTKHNAIPREAKCVIAVNKADVESAK
                     KQINDILTAFKHEFTTSDPGMTYSVAETSVDKVLTKDCKEKVVQMSCLTPHGVQSVSL
                     DIEGLVESSTNFAIIETKESTIEFLTSVRSSVMSIRDEIADRIRLLAQALGANYDLIA
                     QYPAWEFKKGSKLEKICSETYEKLTGKVPTVMALHAGLECGLLLDKLPHAEAISIGPD
                     MFDVHTPNEHVSIPSVANVWDYVIEILKSMNQY"
     gene            complement(38118..40631)
                     /locus_tag="PC466_001529"
     CDS             complement(38118..40631)
                     /locus_tag="PC466_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HDF2768918.1"
                     /translation="MEDCVVNLKKLLLLIIVITSIFTSCIFSFGINAIGNDNRTIRVA
                     YPIQKGLTEIDEQGNYFGYTYEYLLEIAQYTGWNYEFVQVPGEINESITKLMKMLENG
                     EIDIMGGMLYNEPMQKIYNYAGNSYGVANTVLQALYENTDIDNIMSSQDVKKIRIAVI
                     ENSDTRLKELDEYCKMNLMSPELVYCKTSDEQLEVLKSGKADVLLNVSMNPIEGVRTV
                     AKFSSKPFYFITPKGSTDLTQKLNSAINNIEQKDPYFSTTLYEKYFTPENNQMFLSDE
                     ETNYIKDTEKLKVGVLLNKPPFQNADKDTGELRGISIDLLNHICDKTGLEFELVPVKS
                     QEDLEDMAKKHEIDIVAGMIYDYEYSREHNIAMSRPFLSTQYTMMINNKLNENSLNGK
                     RIALAKGIDYYGQFEENIVWYDNLEECIEAVNKGYADYTYGEGYSMQYYMNQPKYKNV
                     RLVPQTYEAKSICFGIIKKDKQELLNIFNKAIISISSEKMQSIVYQNTTYRQDFSLLY
                     IMQQNPIETIFIVASLLICIIGFMAFGLHTRTSMNEKISLELKKHTQLYEMTSEYFFE
                     YDYKQDKLIISMPEKGIETYYGLDKSDKESENGNIENERDKIRREYNKKFFDVIKSQE
                     NGTTEMYSIMLDDTFHWIRITSKIIYNDRKIPMYVIGKIANIDSEKEEKNRLLDKVQR
                     DSLTNIYNAAYIRKLTTQNLLNLSTEKNGALLIIDIDYFKSINDTYGHLVGDKVLIDV
                     AKVLDESFAKDDIVGRLGGDEFSVYINDIINKEELINKCNDVYNHIHLIKLPNGESLS
                     ISMGVVITKRGQEYDELYQIADNALYDSKRQGRNRFKIV"
     gene            complement(40854..41675)
                     /locus_tag="PC466_001530"
     CDS             complement(40854..41675)
                     /locus_tag="PC466_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDF2768919.1"
                     /translation="MIDINLEKCVGCGMCESDCLVNAIKVKDDKAKVKNILCINCGHC
                     MAICPTDAIEMQGFDKNEVIEYNRESFELEPEKLLNFIKFRRSIRQYKDIEVEEEKIK
                     NIVEAGRYTPTGGNRQPIRYILVKEKLKEVKELAIQGLYNLALDTDDNDPVRSIYKNT
                     FKKMYKRYKENGNDSLFYDAPLLMIVVGDMSLGGSAYVDGGLAASNMELMAYSQGLGI
                     CYNGFFVMASNVEPKIKELLGMSENEAVITSFILGYPDVKYKRTVNRNTAKFEMR"
     gene            complement(42194..42670)
                     /locus_tag="PC466_001531"
     CDS             complement(42194..42670)
                     /locus_tag="PC466_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HDF2768920.1"
                     /translation="MKLTTICYIEKDDKTLMLYRNKKKDDIHEGKYVGVGGKFEQGET
                     PEECVIREVKEETGLTLKSLSYKGLITFPKFKDEEDWYMFLYFSDEFEGELSEKDLND
                     CKEGNLIWVGNDKIFDLNMWEGDRLFLNWAKTGNIFSAKIVYDNGKLKDYNVSFLD"
     gene            complement(42704..43282)
                     /locus_tag="PC466_001532"
     CDS             complement(42704..43282)
                     /locus_tag="PC466_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HDF2768921.1"
                     /translation="MREEALEILFKYLETDRMRKHCYAVEAVMRELAKRLEPEKEEEW
                     AVAGLLHDLDSDIVGRKPGEICEGHATTTVELLKKENFGDEEMYRAILGHHDGMGVTR
                     TSLMEKAIYAADPITGFITAIALVYPDKKLTSVKTKSVIKRMKETRFASNVNRDAMRS
                     IEDIGIPFDEFAELSLNAMKNISDVLESAENN"
     gene            complement(43386..46004)
                     /locus_tag="PC466_001533"
     CDS             complement(43386..46004)
                     /locus_tag="PC466_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HDF2768922.1"
                     /translation="MKKIELLAPVGSFDSLKAAVQNGANAVYLGGKDFSARASANNFD
                     RNELIEAVKYSHIRGVQVFVTVNTLIKQYEIEDFVEYVKFLYDIDIDALIVQDIGMAR
                     LIKKLLPDFELHASTQMVAHSLEDVKYLQSVGFDRVVLARELNVDEIKWICENTTVDI
                     EVFVHGALCVCYSGQCLMSSMIGNRSGNRGRCAQPCRQKYELIDINTGEVVKSNGDYL
                     LSPRDLSTIEDLDKIIETGVLSLKIEGRMKKPEYVATVVSGYREAINEFVDKKKISIS
                     EEIINNLYTIFNRKFTKGYILGEVGKDIMNSNRPNNQGLYIGKVLDYNRKNKRLRVML
                     ENTLKKGDGINLGGGTIGRIIKDGEITTIAHKGDLIELDFVGEAKRNQLIYKTSDSEL
                     MNRVQATFQQDKEFIKTNIRAKVSIKLGKKPELFISDFCGNKSVVEGDKIVEKAIKVA
                     LSKEKIETQIQKLGNTPYKLKEIEIDLDEGVSMPISVLNQMRRDCIELLDEERIKIKD
                     RKFKKNRLKYQPNRVNKQKKLDTVPKIRVKVKNLEQLEAVLNYNVDLIYYEDINTLSK
                     ALQMASSISIDSSISIDSSISIDSSISMDLDTSSSLGIPKELMGSNTNNIDTLSNTSK
                     IDTLNKNHYNTAVTDKKLIYSAPRIVRNKEYKQFEILDNIKGINKVQIGNWGSMEYFK
                     KKDLNIDCYLNAFNSESINHFKEEGASTVCLSQELNLNEIKQTLKYTDVEIEAVIYGY
                     APMMVTEYCPMGVVVRDCKKDKRVAKCKESSYALRDFTDASYRITQDIFCRSTIYNSK
                     VTCMLDNLYELEEIGIDVFRIDFTVEDSEMVKKVIEAHIEVLSNNYKLGKKATDLYKK
                     LDEIGTVAGHYYKGVE"
BASE COUNT        14045 a         8903 c         5111 g        18045 t
ORIGIN      
        1 aaaagtttta aataaagtta tattttttac aacagttttg taattaaaaa catattgaag
       61 gtaaatttaa aggtactata tactataaat atgtcgacac aataaattta aaaaggagaa
      121 ctaaatatga aaaaaagatt aataataatg atattgtctg ttgtcttagt actatcaagt
      181 atacttacga tatttgcata ttcaaatatt aaatataata ataataaatt gatatattct
      241 aatatgatag ataaaaaaac tcaaaatagt gtaaaggaaa tcctaaaaga aaataaaatt
      301 aatgaaaaag acatagatac atttattaaa gcagtcaaca attataataa attgcaagtt
      361 aaaatacttc aaaataatat aaatatatct aaatctggat attcttcaat caatgcaaaa
      421 caagttccat ataacctaga aaaattgcaa gataattggg tgaaaaaatt ccctgattat
      481 atggatgtaa attgtagaat aactgctttt agacttttta aagattttat aaattcaaat
      541 aagaaattta ctggagactc tattgatttg aatgtcgact tagacactat aatgaataat
      601 aaagatgcta aatttagcac caaagatgta gaaaaattta tcaacttctt ttctgcaata
      661 ccagctaaag atacagatga tacaatcaaa attgcagaac aaataaaaaa tgaatggaaa
      721 aaaagaaaaa tatcttttaa aaataataaa aatatatcta ttataaatgg atttcttcgt
      781 tatccagaaa ctaaaaacgt atttataggt catacaggca tatgtattaa aactaaaaat
      841 ggcattctat ttttagaaaa atatggtgtt acatcacctt atcaagttac taaatttaaa
      901 aataaaaaag gtgtaaaaaa ttatatgttt aatagattga agatgtcaga aggtgaaatt
      961 gaattgcctg accctataat aatggaaaac gataaactta tgaaataata actttaaacg
     1021 caaaatagta tttataatta ctaagtcaat ataatagaga aggtctatag atttgtgtaa
     1081 atacaatctt atctacaatc ttatataaga atgtttatat aaataagata gattaattct
     1141 aagtcctatt attctattga attttattat tattttactt agattctatt gttattttac
     1201 ttagaactta ttgttatttt atttaagttc tattactatt ttcaatcata taaatttaca
     1261 aaagactgta cataaattta ttttatacaa acttatctac agtcttttgt gtgaatatat
     1321 ctaaataata tcgtatttat ttatttcctc tgcacagtga gaatcagaac ctaaaactaa
     1381 tggaatatcg tattttttta ccaactctaa taagtatcca tctatataag gctctttgca
     1441 atactctttt ctatttccag aaacattata atcaagttca taaccttttt ctttaattaa
     1501 ctttattaag tcttcaagaa ttgtatttcc tttataatcg tatggaaata cctgattaaa
     1561 ctttctaact aaatttaaat gacctattct ttttggttta tgtataccta aatctgaatt
     1621 tacagctttt atcaatgttt cataatactt attataaaca gcttcaatac ttcctaattt
     1681 gtcgattaaa ttttgaaact cctctacact gtaatctaca caataataat catcatcaat
     1741 tttaattata tgtactgata aaagagagtc ttctaattcc tttccatatt tatttaaatt
     1801 ctcctttatc ccttcttcgt atccttctat aaaatccact tccgacccaa catttatctt
     1861 gattttaccc tcatactttt ctttcaactt cttgacatca ttaaaatact ttggtaaatc
     1921 ttcaatactc atacaactat cattttcagg agcagggtct ctaaatccat ttgcatacgg
     1981 aaaatgttct gtaaatgtca tttctgttat tccaacatcc attgctcttt gtacatattt
     2041 ttcaaaatca tccttacttc catgaggaca ataaggtgaa tgtatatgac catctttcat
     2101 aaataattca ctcctttttt aaagaaaaaa tctaatataa atgcataaat tttttaactt
     2161 caaaataata tttttaatca tgctaatttt tattatatct aatattagag taattttaaa
     2221 ctgcctttta agtatcttat ctttagtact attttcaact taacattaat attatttttt
     2281 aacttaacat taatactatc tttaaatagt aatactcaat atataattaa tcaaataact
     2341 caaattgttt gatgaagctt ttgcagtatt taaagaatat ataattattt aacattaaat
     2401 aatccaatct tgtaataaaa tttactcatt aaagtatatt acagaaaata tctcaaaata
     2461 aactttttag ttcatgatat actctttttt gcatgaaatt agatatattt ttatcatttc
     2521 aacaatgaaa gggaggctta catccatctt gagataaccc cttagataaa atttttaata
     2581 attaaacatc ataaaatata aaaatcgctt atatcaaacg tataagcgat taattatatt
     2641 tacatatgtt ttttagcctc taacaacatt ttattagctt cttccatata ctctatagcc
     2701 ttttcaatac tctttgctgt ttcttctttt ccaatagctc tagccttttc aacccactct
     2761 ctaaatcctt cttcatgagt ttcattgtga tttatccaat gtactaaaag tatttttaaa
     2821 gttttttcat ccttagactc tgatgattcc tcatgactat gttcatggtc gtggtcgtga
     2881 gcatggtcat gtggatgttc atgacatata tctccatgag tatgttcgtg gcagtggtca
     2941 tggtcatgat gtccatgatg atatcttaca atctctttat caaaaatcat tagttattcc
     3001 ccctgttatt ttatattaaa ctcttttttt ataaggttta cagaatcttt tacaagtagt
     3061 gctaatggtt taccttctaa tccaactaac tccacatttt ctggcataat aggtaaaagt
     3121 atcttaagtg cctcactgtc tgcaatagct tcacttatat tacaagtaac ttctcccatc
     3181 atagaattag gtattattac agaaataggt gcaactatta tatttgcttt tttagctgat
     3241 actactatag cattttcccc tgtagctcct ttattagcat gagctttcat catagaacta
     3301 gttgctatag aattagtccc tagtgcataa atttctacat atgtaggtaa ctcttctctc
     3361 aaagaagaaa ctatctgggc tccaatacct ccacccattc catctatcac tgctattatc
     3421 atatgaaatt cccctattaa ttaattttct tgtattatta tcttatggtc catcaatctt
     3481 atttctttaa ttatcccatc tattatcttt tgctctccta ataaatccgt taaataaatc
     3541 tttccatcac aagggtctat attaaccaca ttttccataa ccttttctaa ctcattatta
     3601 cttttacaaa tgaaagctga tgattcacac atataaatct cctcctaata tgatttttat
     3661 taaaaatcaa aaaaagattc ccttaggtat ttcaatactc caaagaaacc ttcatgattt
     3721 cagtttttgt atattattat accttaagta tatcacttta atttatgtaa agtcaattaa
     3781 agttaacgct ttttattata ctcttcattc ttgtattttt catatagttc tttaactaat
     3841 tgcttctcat aatcagtcaa atcgccctcc acaaactcaa cattaaattg ttcagctaat
     3901 ccctttacta tgtttttctg tagaatatct atgtctattt ttctgccaat ttcattttct
     3961 attccacttg cttttttagc tgtaaatttc atagctcttt ctttcaattc tggtgtctta
     4021 gtttttatta atttaaacaa tttttctaca tcaaaatcca gtattattga accatgttgt
     4081 aataaaacac catcttttct gctttgagca cttccaatta ccttcttatt attaatagta
     4141 acttcatatg atgcatgtgc attaaaacat gcagctgata aattttccct acttattctc
     4201 tcgcctctat ttaaattatc tgtttctata ccacttagat tcaatccttt aactagacct
     4261 tcacttatat atctataaga taggttgatg ctcttatcga ttaaaggatt atcttctcct
     4321 ataattatac tataagttag ctcattatca tgtaatacag ctcttccacc tgtaattctt
     4381 ctagtatagt ctatattcat acatctacac ttatctaaat ctatctcatc ttccaatttc
     4441 tgaaaatatc ctatactcaa acaagctggt tcccatgtat aaaatctaag agttggctta
     4501 ttatgtcctt tcttatatgc agtaaatata gcttcgtcaa ttgccatatt cattgctcct
     4561 tcatatgatt tattatgtat aactctccac tgattcatga ttattacgcc cccattttta
     4621 gtataaatat atcctagaaa tcctctatag atttatttct cttattgcta aatctatctc
     4681 actttgattt aaaggtcttg aatagttgta tatagtactt ccgggtcttt cattatagta
     4741 tggtctatta caatccttac aacctcttat ttcaaaagga tagcctttgt ttatgtcttt
     4801 taaaatatca ttgtcaagct ttatactatt taagtatcca tttttaaact taaaatactc
     4861 ttttggataa cctttattta tcatataaga cattaactgt acccttctat aactttctat
     4921 gcttggttga tttatctttt ccattttagt tcctctaact ggagtaaatg caaataaact
     4981 aatcgttaca tcattttcct ttaaataaat atataaattg tatatatctt catgactttc
     5041 acccatacca actattatat gtgtacttat tttattggga tatgattttg acatttcagt
     5101 tataaatttt aacttttcat catagttatt tccttttatt ttttcatata gttctttatt
     5161 tgatgcatct attgctattc ctattttatc aactcctact gaaaaaaact tctttatctg
     5221 ttcatcattt tctaattttg cagatagtga aattggcatg tctatcttac cacttatata
     5281 gtttataaag tctaaaacag agttatgtgc ttcttcactt gccattgatt gaatacatat
     5341 tctctttata ttttttcctt tataagcttt taaagcatct aatatttctt cttttgaaaa
     5401 ctctggccaa attactcttg ataatttatc ttttctagta ctactttcta ttgattgaga
     5461 acaaaaactg catttattta tacatttttc tccaatcatt atatatgctg tggtaggagg
     5521 tatatcgctt tttttgttta atatcccaag ctctattgct gtcccaactg atagtctaat
     5581 cataaaacgc aacactcctt acactcattt attgtcatat tcatttctat agccttattc
     5641 tttgcagacc ttgatggtaa tactattcta ttgactccac acattataga taattggtct
     5701 agctcttttc tatacactcc tcttggtctc atacaaccta gattaatttc agtatctggt
     5761 aaattaattc tagcttcaca taaaatatct gctacccctt ctaactcagg aggttctaca
     5821 ttttcatact cagtcccttt tgttggaata aggactataa atgtaagctt attaggagga
     5881 tttttctgta ggtattctat aatttcatat tcacccttta tttgtcctcc ttttaaacca
     5941 atacatatat gtggtgctac ttctgtatgt tcttgtattg tattataaac ttcaatataa
     6001 tcttctttac tctttttcat cttataaact tctcttattg tctcatcatc aaacactaaa
     6061 tcaaaagaaa ctatatctaa atacttacac aactctacaa tgctatcttt atccataaga
     6121 cctaaatgag cattcaatct atatcctttc tcttttaagt ttttaatggt attaatatga
     6181 gtatttatag ggacatctcc ctcataacta caaccgccac tcaatagaaa gctagttata
     6241 ttccttgatt gtactttttc ctcatattct tctattggca ccatattgtt taagtagtga
     6301 ccgttgcaat gggcacattt caaactacat tgattgcttg tagtactaag agctagtgtc
     6361 tggttaggat aagcaaactc tattttattt ccaaaattct ttaatttaat atcaaatgct
     6421 attttcattt tttcagatag attcttattc atagtttatt ccttcttaag tacattttac
     6481 tcttctagta atttctttgc tgttgggaac tgctctatat tcgtatgtgg taagaaacat
     6541 gcagaaataa attcatccat ataacttgga tatacactaa gttcaacata agttatttga
     6601 ttacctattt cttcaagttt attttttgca tctttactta tgagagctaa gtaagaacca
     6661 acaagtgaac tattccctat ataagtaaat ttttctctat caatgtcagg aagtaaccct
     6721 ataattattg agttttctat gtctaggttg tttcctatac cacctgctat ataaacccta
     6781 tctaatatac taaaatccat acctaaacta tctacaagag tgtatgcacc tgaatatata
     6841 gctcctttag ctctgatgaa attatctata tcaacttcat tgactactat atcattttct
     6901 aaatcaaatt cttctttaaa tgctaataca tactctccta tctcatgctc attaaatcta
     6961 actctcttat tatctaaatc cctgtatatt ttacctcttc tatctattac acctttagta
     7021 atcatttgac agattaaatc aattatacca gaaccacata taccaactgg tgcacattca
     7081 tcaataatct ttaatgttgg ctctaaagtt tctttatcaa taattacttt ctctattgct
     7141 cctgctgatg ccctcattcc acagcttatc cctccacctt caaaagcagg tcctgctgaa
     7201 catgcacagc tcatcatata atctttattt ccaaatacaa tctctccatt agttcctaaa
     7261 tctataaata aaacattttc ttcacttgac catatccctg ctgataatac acctgctgtt
     7321 atatctcctc ctacataact tgcaacagat ggagctaagt acacatatgc actgtcattt
     7381 acaaaaagac caacattttc acccataagt tttggagatt ttaaaaatgg tggtatgtaa
     7441 ggttcttgtc ttaagaagtc tgtatacaca cccaagaata aacttgtcat agttgtattc
     7501 ccggcagcca ctaatgtaac tacatcttcc ttatctattc catttctttc atatattgtt
     7561 tttaatagtg gatttatagt ttcctcaact atagctttat gaagtgtctc taatccattt
     7621 ttcttagttg aatatataat tctatttata acatctgctc catattttat ctgtgcattt
     7681 ccagaagatg ctttatctac tacctctttt gaatataggt ctactaaaca aacaactact
     7741 gaagttgtac caatatctat tgcaactccg tataaggaat tttctttatt accttgttct
     7801 atatttatga ttgtaagttt cttttgtttt tgaacatatg ttattgtaac cttaaaatca
     7861 ctctttctaa atacagttgg catttttcta agtatatcca atctaaaatc tatttcatta
     7921 tatcctaggc tatttctaac atatctttcc aatctatcta catcacttat attatcatct
     7981 aaatttggtt cttccatttc tatgtatttc ttttttatat ttgttttaaa ttgaaggtta
     8041 tgttcttcaa ttattttttt agctctttca aaaatttccc tatcctcttt tttattacta
     8101 ccttctatct tcataccatg catagaagat gatactttag aaggaacttc aatttctata
     8161 tctgatatta cctttgtaca acaagctagt atataacctt gctcccactc atcatctgtt
     8221 atatgtcttg ttttttctgt atcaactttt ccattcaata attttacttt acacttccca
     8281 caagacacgt ttccattaca aggagcatct atgaatatat ctgcatttct tgcaacctct
     8341 agtaatatat caccctcatt acaataaacc tctttattgt ttggtgtaaa actcactttt
     8401 atcatgttat ccctcccaat ttgttctata tatgataaaa ggaaagtata gctaaatttg
     8461 cgtgcactca aattttacta tactttcccc aattataata atatcttaat ctttaattat
     8521 tctaatccag cctcgtattc tttatcactt aataacgtat caagttcagc cacatcagct
     8581 agttttactt ttaatatcca gttttcatat gggtcttcat ttatacattc tggctcatct
     8641 tctaattttt cattaacttc caatacctca ccattaacag gagatattaa atcagaagct
     8701 actttagaag actcaactac tccaaaatct actcccttag ttacagtatc ttctacttct
     8761 ggtgtttcaa caaacaatat ttctcctaat tgatcttgag catagtctgt tatacctata
     8821 tatacaacat ctccatcaat tacttttacc cactcatgat ctttagagta ttttaattct
     8881 ggtaataatt tcatttcgat agacccccaa tattatatta ttgattaaat tacttaaatc
     8941 atattaatat tatatcatat tattttaaat tttccatcaa ttacattaca ctttccatag
     9001 ctaatgctgg atgacctttt tcttctaaga aagctaatac tccttcagaa tcgtcagcta
     9061 tagtttcatc acaaaccata tcacagaagt tttctattcc agtcatttct ttaactgtag
     9121 catttaattt atcagctaca taatctttta attcttttgg catccaaact attctttctg
     9181 gtccaccttc tgcataagcg aattttttag aagatatgaa atgtcttccg tgtcccataa
     9241 atcctggagt ttgaactcct ccacctgtca tagaagcaag ttctccgaaa gtcataccaa
     9301 ctggagtaac acttgcaaat tctctgttaa ctacaacaaa tccgtttgct tctggcatta
     9361 taccacagat acattcgaag catccacaag aagtcattgg gtcttctagt atagaatata
     9421 atgtaacaga ttcaactgca ccttgagata tttggtttac agtttcattt actgaattcc
     9481 atacacctgt tctatcatct aagcactcgc ctttttctat tggttgacaa ggacctgttg
     9541 ggtctaattc tttagtagcc ttagcatcta accagctaac tgctccacaa agaccaagtc
     9601 tttcaggagt aacaacacaa acgtgagctg gtgcaaatga ttgacataag ttacaagaat
     9661 agaaagtatc aacactttca tcaactaatg aagctaatct ttcatctcta gcattgtact
     9721 tagctattgc ttctcctttt aattcagaca ctttttcagc atctgtaatt atagttattt
     9781 cacacttatc aactactgat tcaaattcat ctaacatctt agcatataaa acttctccta
     9841 tatgctcaag tctaaatcct ttatcaaatg catctttaga gattcttacc caagccatat
     9901 ctctttgtcc aacgtgcatt acaccttcta tatagttcaa gaagtagtgg aaacgtcttt
     9961 caagaactgg ctcgaaatct tcttgcatat ttttaccagc tattttaact attacagcaa
    10021 gcggtaatct taatacacca tctgcatcaa cttcatctat atttggtcct attatttcta
    10081 tcttatggtc ttcaacttct gttgcttctt tcttaacaac aagctcccaa gcttcagttc
    10141 tgtttccacc aaactcagca aacatatcgc tctttctaat tctctcacct tcaaatgctg
    10201 ctgcaaatga aactgggata ggtatttcag taacttttat ttttattcct ctagcttcta
    10261 atgaagtagc tactatctta tcgtaatctt tttgagttaa taggttcatt ggaacttcaa
    10321 gaactgtttg gtcagttata actgggaatc ctaaagctat tgctccagca cctgcagata
    10381 caactaattc acttaatggt ccaaatgcat taacaaatgc aggaactcta ttagctgtgt
    10441 actctaataa tccgtttaaa tcaccaggag ttaatccacc gaatattaat gctgctctta
    10501 ctgcaacaga tacaacgtgt ataacagaag ttacatcata tcctagaggt ataactctta
    10561 gctcaagacc catttttact ccagcttcta tagcttggtc tataacttta ccaactaaga
    10621 aagttagtaa acctttagat tggtaatctt ttataacttt tgctgctgat tctgcatctg
    10681 gacactcacc aagaacaact gcaacaccag gtatatctcc tgtaactaat ggtacaccaa
    10741 gtgatctgat tatagggtca gttatatgac ctgcacatgg ctcactatat ggagcatcca
    10801 tagttgaata ttttaatgct tcaattactt ctgcagctaa agccgtagct aaaccagcat
    10861 taaaagcatg ttctagtaaa tgagttctat ttattaaaga ttttactact tctaaagcac
    10921 cttctaagtc ccctaaagtg ttcatctttt gtcctgttgc agcatatata caaggtaatg
    10981 aatatgctgt atcagggaaa gcaactttat gctcttttcc attcttttct atagcttcag
    11041 ctaacatagc ttgagccgca cctaaagctt gttctgaccc tgtaaagatt atattatata
    11101 gattcattct atttccccct ttaatattta cacctatttt ttattaacta taccctaaaa
    11161 accctagaaa gcaaatccac cttcatttaa ctctaagaaa gagtctgcat ataaagatgc
    11221 cccgttgatt atgtcacaag attttacagt tttcattaat tctgggtcac atggattcat
    11281 tatagctgaa ctaaatccat tagccattgc cattgctaag aatgcactat ctaaaacagg
    11341 tctaacatgc ttaggacatc cattagatac gttagataat cctcctgtag ttaaaagtcc
    11401 catctcagtc atcattttta tagcttctaa aacttctact tgtttttctt gcataccttt
    11461 tataactaag cataatgggt caaatagtat atcagttggc tccattccta acattaagcc
    11521 tttttctaat atttcttggc agtaagccat acgctcatca ttatctcttg ggataccttc
    11581 ttttgcacat aaacctataa ccattgcttc gtattcagct gctatatcta ttaaatcaaa
    11641 tcttgagcca gcatcagcag agtttattat tggttttgca ttagttctat cataaacttt
    11701 aagtccagct tcgatagctt ttttattagc tgtatctaat gctataggaa cattgttgaa
    11761 ctcagattga agtaatttga ttccccatgt cattatttct tcgccatctc tttcggcagg
    11821 tcctatatta aaatctatat agtgtgctcc tgcttctaat tgctcttttg ctctttttaa
    11881 gattggagct gggtctcttt ctgctaatgc ttttcttatt gaaggtgata tacaatgtat
    11941 tctctcacct ataatcataa atttttccat ttataatgtc cccctttaaa tttaatatta
    12001 atagttagtt aatattttat tagtttgttt ggcatgcttt ttcttggtat ccttttaaga
    12061 acttaggtaa ttccatagat tcctctggtc ctataactac attccatcct ggtaagttat
    12121 cttctatatc acctttaagt actgcaactt ttcctggaat gataaggtct ttacaattag
    12181 ttacttcttc taccttactt tctttaatga aagcagagat tgagtttcca ccaaatttac
    12241 cagcagccca agatgtaaga actgaatatc cacctgcatc tggtattact aaccatactg
    12301 gaacttttga tctttctata tcaccagcaa ctatgaagta agttaatgca aagtcaacag
    12361 taactaatac tggagaattt tcatctgggt tgttgattgg ataaatcttt ggttcaactc
    12421 tcattggtct ttgtgggtca gtgtatatgt tttgtcttag tgcaaataat ggtaatgcct
    12481 tagcataact aatatcatct attactatta tagaaccgta ttttatagtg aatattgatg
    12541 ataaagcaac ttccatcata gggtttgaat tagataatct atttgcaaat actattgaag
    12601 gatatccaaa tgttctatct tgctctttta aagctgttct tctaacttgt atagcattag
    12661 tgtaagtatc ttttatgttt tctcctgtta catctaatac taattcttta tatccagcgg
    12721 cttgaattaa ttcaactgtt tcatataatt cttctaagct accagctttt acacctaatg
    12781 gtaaacttgc tcctttaact acttctatca tatctttgta gttctcttta gttgctccat
    12841 ataccattgg tctagcatct tttaatactt caacagcttc tttaactact tgtgcatcat
    12901 cacaagctaa aatataagct acttctaatc cactgccttt tattttatct attaatttta
    12961 aatacgcatc tttatctcca caatactcta aaacagccat ttcaactttc atttgttcac
    13021 caattcttac atagtcaact tttttcatgt tagctatttt agcatctact gcttcatcac
    13081 tcatacaagt acagaatgaa actgcatatc tatttctact tactaatgtt ttttcatgtc
    13141 taaataatac tgtttctcca cctagttcat actcagatgc accagcacca acttttaaag
    13201 ctttcattaa aggtgcagta gcctctgata attttgctat agcgtcatca gacatatgtg
    13261 ggcatttacc tacttctaca gctcctgaag caaccttcat agagaaagcc atacaagttg
    13321 ggaatccaca atccttacag tttttctttg gtgttaattt aaatatatct aaagctttta
    13381 atgccattat tttttccccc taaccttaac aatttaatta agctaatgcg ttaaccaatt
    13441 cttttatagt ttctattgat tttggatgac gaagtataac tgcgtttgaa ccacctacta
    13501 aaacacttgc tgcagttgaa acttccattg ctatagttct ttcttctgga caaccccaat
    13561 ctggctcatc ttctattgga gctatagctt ctttaacatg acctacttca aaagctactg
    13621 gtgttatgat aggcatttgt aatgtcttat cattttgacc aaatgctgca agtctaattc
    13681 tatccatagt agatgcaacg tactcatatc cataaccaac tgctgaacat ccaacattca
    13741 taactatatt ttcaccttta acgcctagtt gagttaacaa tacgtttaat tgtttagcta
    13801 ggtttatatc aacagaagat tcagctccta ctttatgtgc ataagccata ccagctgatg
    13861 ctcctactcc tttgtagtta tcttctactg ctgacataaa taagcagtta tgtccatcca
    13921 atgtttgagc taatttttca aataatttac catctttttc atgatttcct gaaccagcta
    13981 caactaaagg taattttatt gcttcaatta ctgccttagc tacatcagca cattcatcaa
    14041 ctgacttatc taatccattt gggtcagaac catcaaattt taaacaaata aaatctgctt
    14101 gtgtattagc ttcaacatat ttagcccact ctactggaca attagctaca tctttgtata
    14161 attccttata tgaatcagtc cagctttcag gataaacgtc tgatatttgt atacctattt
    14221 ttggagaatt acctacttct ccatcaaaac tataaaaagg taatacattt tccccaccta
    14281 atttaattgc tttttcccct attcctactt caacttctga tatttttcca gaatattttt
    14341 gagtagacat tttaaatgcc atattttttt cccccttaag cctattttaa ttctaattta
    14401 gcaaaaattt ctttcatagc cactttagat tttgaatctt caggtaaatt aactaaagga
    14461 atacctgtag aatcatattc atatatcaat tcatccatag gtacaacacc gattagctct
    14521 aggttatgct tttcaatttc ttctttaaca ccatcattca taaccccatt tggaacttta
    14581 tttacaatca aaagtattct tccaacactt aactttagtt cctcagctaa atctcttatt
    14641 ctagcaacag cttgtatgct acgtcttgag caatcactaa ccaataaaag tgtatcaaca
    14701 tgtctagtga cttttctact tagatgttcc ataccagctt cgttgtccat gactaagtat
    14761 ttgtaatgac cagatatttt gtttacttgt tctctaagta tcccatttac aaaacagtaa
    14821 catccttcac cttctgacct acccattact aataagtcat atccttcgcc ttcttcgatt
    14881 atagaattta atctaaattg aagatattgt gcctttgtca taccaccagg gaatgcattg
    14941 cctaactttt ctctttgatt tacttcttct cttatttctc ctattgttgc ttcaacttcg
    15001 atacctaaca cttcatttat gttagcattg gcatcagcat ctacaactaa tactggtccc
    15061 tttttgtcct taaccaaata atcaattaaa agccctgtga gacttgtttt accagttcca
    15121 ccttttcctg caacagctat attgtatccc attttaagac ttccccctta aatctagcca
    15181 cagagcctta tgtactctgt ctgtctatta taatttaggt acagaatgaa cacattctcc
    15241 atgtacatca tgaagtgctt ccattagccc ttcagataaa cttggatgtg gatgtattgc
    15301 atcccctact tgttctactg ttaatcctag atgaacagca agtgacaact ctgtcaataa
    15361 atctgtagca tgaggtccta ctactgctgc acctattatc ttatcagttt ctttgtcagc
    15421 tataactttt acaaatcctt ggaaatgtcc tatagcttgt gcttttccaa gacctctaaa
    15481 atcaaattga cctacattgt attctacacc ttcagcttca agttgctttt cagtcttacc
    15541 aacaccagca acttcaggtt cagtataaac acatcttgga attgctctat aatctactac
    15601 cttagtctta cctaaagcat tttcaactgc tacgatacct tctttagaag caacatgtgc
    15661 taggaaagga gtatctatta tatcgcctat tgcgtatata ccttctacat tagtttcaag
    15721 atgttcatta actactactt ttcctctttc catttcaatt cctatatctt ctactccaga
    15781 attgtcaagg ttaggtcttc taccaacaca tactaatgca tattgtgctt ctataacctt
    15841 tccattagaa agagttgcaa ccgccttacc atcaactact tcacaagttt gtactccaat
    15901 acctgtaata accttaattt tatctttctt aaattgtcta agtagttgtt tagctacatc
    15961 tttgtcttca tttaatagta tttggtcaac catctcaact atagttactt ctgttcctaa
    16021 ggctctaaag aactgcccta tctcacatcc tataactcca ccacctacta ttaacataga
    16081 ctcaggtatc tcttcaagtc caagaacttc atcactagtt attacaactt ttccatcata
    16141 tgggaacatt cttggtacaa ctggaacaga accatttgct agtattatct tatctgcttt
    16201 tatagtttct actgttccat catctttagt tacttctata gtgtttttat caattaattt
    16261 tccaaaacca ttaactaagt ttactcctct tttttcaaat aagaactcta taccacttat
    16321 taattggttt acaactttat tttttctttc cattatggca gtgaagtttg gcttaactgt
    16381 accatctatt tctataccaa aatcctttgc ttcttttaca gtattcaata ctcctgaaga
    16441 agcaagaagt gctttagttg gtatacatcc tgcatttaag caagttcctc caactcttct
    16501 tttttcaata accgttacat ctgcaccaag catagaagct tttatagctg ctacatatcc
    16561 tcctggtcca ccacctacta ctactatctt catccttaat tcccccaaac ctaatataat
    16621 ctacaatctt gcaatactat aaacctgcgg catccagtat agcaggtata ttctcttctg
    16681 ccccaattgc cattatatga acaccatcac ataaatcttc ttcttttaat tgtttgataa
    16741 gttcccctgc catttttatt ccttcactta cccagttttc ttttccagct gctcttaatc
    16801 tttcgatttg ttcatctgga acgaatattc ctggtacatt tgcagtcata aatttagcca
    16861 ttcctggtga ttttaaaggt actattcctg ctaatacctt gcaatccata tcccttgtta
    16921 attctctaaa ctttctcatt gtatttatgt cataaagtgc ttgtgtttgg aaaaatttag
    16981 cccctgcttt tatcttcttt tgcattttta ataattgaac ttctattgga gaatattctg
    17041 gagttactga tgctcccaga taaaaatctg gagaaccttt taacttatta ccagccatgt
    17101 ccgtacctgc cattaaagtc tcagcagttt gaagtatccc cacagaatct aaatcaaaca
    17161 ctcccttagc ctgtggatgg tctcctacgc tagtatggtc tcctgttagt gccaacaaat
    17221 tgtttatccc aaatacacct gctgacaaca tttctccttg tatagctatt ctatttctat
    17281 ctctccctgt tatttgaata actggctcta atccagcatc ttttaataat ttacatgtag
    17341 caagagaagt tgctctcata actgccgatt gaaagtctgt tacatttgct gcatgaactc
    17401 ttccaactaa cggctttgca cattctatta aatgtgaaag gtcagtccct tttggaggag
    17461 ccatttcagt agtaactgca aattttccac tttctaatgt ttctcttaat aagctcatct
    17521 ctaatccccc ttttaacctt ctaaaaaaaa cttttatgaa tttgctgctg cttctttctt
    17581 tttctttgca cttaaacttc ttggattatt ttgcttagaa tagtcttttg gtggtcttat
    17641 ttctgctaag ttatctaatt gtcctatagc ttctagtctt tcatatatct ttatccaagc
    17701 acaatcattc tctgagttta cttcacactt accattttta gctccaccac aagccccatt
    17761 cataagacct ttagcacaca tagttactgg acatatccca cctgtccaac caagttcaca
    17821 gtctccacaa gccttacagg cttcttcata ttctccaact ctttgtactt cccctataaa
    17881 caaagtattg ttggctggat aaactggctt atcttttaaa ttcttaacta ttgtctgtgt
    17941 accatctcca catgctaaag ataaaactgc atcagcttcc ttagtctctt cttttagagc
    18001 ctttaaatcc tttttagact ttaaaaggtt acaagcaggg tcaagcatta catatcctaa
    18061 gatttttttg ccttcacctt caagagtttc cttcattttt aaaacttctt cttccccacc
    18121 acttttacaa gttgctgcac attgattaca accaactaaa accagcttgt caaaatcctt
    18181 taagtaccct agcacttctt ctaatggttt attttcagaa attatcatat ctacttcccc
    18241 cctaaacctt ccacatatat atctctattt attgttttgt aatttacaag ccttaactac
    18301 atgttttgca agtatagatg ttgtaactga accaaccccc gctggaactg gagttatcat
    18361 tgatactttg tctaaaactg catttgtatc aacatctcca cataaatttc cttcttcatc
    18421 aacatttata ccaacgtcta taactaccgc tccatcttta acaaaacttt catcaaccat
    18481 cttagctcta ccaatagctg ctattagcac gtctgcctct gctgctacac ctgatagatt
    18541 tttagttttt gaatgacata ttgtaacagt tgcatgttca cttaataaaa gcattgatac
    18601 tggctttcca actaccattg atcttccaag aactgttacc ttacttcctt ttaaatcaac
    18661 attatagtgt tttaatatct caactactgc tgtaggtgta catggtggaa atccactttt
    18721 atccccttcc attaccttag cagagtttat tggactaaaa caatctacgt ctttttccgg
    18781 tgcaataaca tattttataa cttcttcatt taagtgtttt ggaagaggtc taaaacataa
    18841 tataccatta acatttttgt catcattaac tctctttaat acatcaatat attcctcttg
    18901 tgttatatcc tcagctaact ctaacacttc tgttgttata cctatgtttt gacatctctt
    18961 tagtgctcct ctttcataag ataaatcatc acttcttgcc ccaactctaa ctattgttag
    19021 tttaggattt ataccttctt taactagtaa atcgacttct tttattaatt cttcactaat
    19081 tttatcagct acaggttttc cttttataat ttgtccttta gttgacattc cttccataca
    19141 ttcacaactc ccctacaagc aaacttaaat taatttattc tatataccac atattaataa
    19201 catagtatct actttcgtca tttaaaaatt attttccaag agctttttca actttggcat
    19261 aaacttcatc acaaattttt acaccatctt caactaactt atctacttct atttttacct
    19321 tattaacata ttctttatct tgtatagaat ttatatttat aactacattt aattgtccac
    19381 caagtatagc agctcttaaa cactgaactc ctacaccaac atcacttata gcaagtcttg
    19441 aacctttatc aactaaatct tcatgtaact taatagcttc atagcaaact cttactatgt
    19501 ttaatggtac ttcacaagca acttttaatg ccttttccat tgtttctgct tttattcttt
    19561 tttcttcttc tgtttcttta ggaagcccgt aagcttttga taatggtaag aaacattctg
    19621 catcatcatc tatcattttt aataaatctt tttctaactt tcctgcctta cttaatatct
    19681 cttttacgct ttcttcatac tcagcatact tcttcttccc tattgtaagg ttacatacca
    19741 tactacctaa agccatacct attgcaccta ctagtgcagc agctccccca ccacctggta
    19801 ctgcttcttt ggaagatagt acttctacaa aatcaacaca agttttatct gctattttca
    19861 tgataatcct ccttgaaagg atgtaggaaa atatctcaaa ttattcgaga tattttacga
    19921 actattttaa gatatctcct actctttatt tataaattaa tttccttaga ataatccagc
    19981 tattactcca ttttcatcaa catctatttt ttctgctgct ggaacttttg gtaatcctgg
    20041 catcttcatt atttctccag taagtgcaac tataaatcca gctcctgctg aaattgttgc
    20101 ttgtcttaca gttattctaa atcctgttgg tctacctaat ttagtttggt catcagttaa
    20161 agaatattga gtcttagcca tacatactgg aactttagta aatccaagtt tttctaagtt
    20221 agctatttcc ttatcagctt caggagtata atctacacca tctgctccat aaatcttagt
    20281 agctatagca tttatcttgt cttttataga taaatcatct tcatagcaga atctaaagtt
    20341 attttcttct tcatccaata atcttaaaac ttctttagct actgcaattc caccttctcc
    20401 accttttgcc catacttcag aaagagcaac attaacacct aattccttac acttgtcttc
    20461 aacaagttta agttcagctt cagtatcaag tgggaatcta ttgattgcaa caactgctgg
    20521 taatccatat acttgagtta tgttttcaac atgttttaat aagtttggaa gtcctttttc
    20581 aagagcttct aggttttcgt tatttaagtc tgctttagca actccaccat tgtattttaa
    20641 tgctcttaca gtagcaacta ttataacagc atctggtttt aagtttgcca ttctacattt
    20701 tatatctaag aatttttctg ctccaaggtc agcaccgaaa ccagcctcag ttattacata
    20761 gtctgcaaag tgcatagcca ttcttgtagc tataacagag ttacatccat gagctatatt
    20821 tgcgaatggt ccaccgtgta caaatgatgg tgttccttca agagtttgaa ctaggtttgg
    20881 ttttaaagca tcttttaata atgcagccat agcaccatta gcttttaatt gtctagctgt
    20941 tacaggttca ccttcatagc tgtatccaac tattatgttt cctaatcttt cttttaaatc
    21001 agatatatca cttgccaaac agaacgctgc cattatttca gaagcaacag ttatatcgaa
    21061 tccatcttgt ctaactgctc catcaccttt tttacccata ccatcaacga tatttctaag
    21121 ttgtctatcg ttcatgtcca cacatcttct ccaagttatt ttcttagggt ctattctaag
    21181 tgcatttcct tggtgaatat ggttatcaag catagcagct aaaagattgt tagcagctcc
    21241 tatagcgtga aaatctcctg tgaagtgtaa gtttatatct tccataggaa caacttgtgc
    21301 atatcctcca ccagctgctc cacctttaac accaaatact ggtcctagag atggttctct
    21361 taaagcaact aatacatttt tgtctagttt agcaaatgca tcagcaacac ctatagtagt
    21421 agtagttttt ccttcacctg ctggagttgg atttatagct gtagttagta ttaacttagc
    21481 ttttttacca gtctctcttt ttagtagatt gtagtcaact tttgctttgt atttaccata
    21541 aagttctaca tcatcttcac ctagtcctaa tttttttgca acctctctaa tatcttgagg
    21601 cttagcttct tgagctattt caatgtcaga tttaaatccc ataactgaat ctcctcccac
    21661 aacctaaata gatttaaaat ataatttttg taaaaattgt attaatatgt aaaaattata
    21721 ttttataaga taattataca tgtaaaatta cttaaaaact agctactaag ctattaaaat
    21781 attcaaactt aatagctagt tatttatcta attacttact tattacctat ctattgccta
    21841 tgtctaacct ttaaccaact taaaatccca aatcaaaatt tctatctatt ttatttatcc
    21901 ttaagtgaca ttaatttatc ttttattgct ttaatctgtt ctttcgttgt ttcactagaa
    21961 tcatatggag attgattagc tctatcagaa tcaataacat cttggttata gtaaataaat
    22021 cctaaagatt ctccatcttc taagttttgg attataaatt cttcatcttc cttatttcta
    22081 attttatttc ctactacaaa tactttattt acacctatat catgtccaag tttcttaact
    22141 tttctataag tctgtagact tctctctcct ggttctacaa ctactataaa agcatctaca
    22201 ccttgggctg ttcctcttcc taagtgttca attcccgctt ccatatccat aaccactaca
    22261 tctttatttt gtagtattaa atgtgagcag agtctcttca aaagaacatg ctctggacat
    22321 acacatccag taccaccaga atctacggtt cccaatgtaa gtaatcttac tccattgtat
    22381 tctttacaga aattttcagg gatatcgtct actttaggat tcatcttaaa catttttcca
    22441 aatgaaccta cagaagcagc tgttctatct gaaactaatt ttttcatttc tgatataggt
    22501 actattgatt catatacttc ttttggaaaa cctagtgcta aagctaaatt agcatcaggg
    22561 tcggcatcaa cagcaacaac tctgtatccg tcttcagcaa acatcctaga gagcattgaa
    22621 gaaaaagtcg ttttacctac tccaccttta cctgttattg ctatcttcat aatccctacc
    22681 accttttatt actatttgct ttttagtagt taattttaca gttaaatatt ttttatactc
    22741 tatattttta tacactaaaa ataaactaca gctagtcctt acaggaacca attaaattta
    22801 ccctactagc ttttcaaagc agcatgtata gttttattat tctttaatat tgtttatatt
    22861 ttatttattc agtatattca ttatatttcg atgttcttta ctttaatatt tgactttatt
    22921 caactttact caaccagaaa cttcttataa aaacgtttat tctataactt cactattttt
    22981 taagcttcag ccttttctgc cattttttct tcaactaatg cttcaaagtg aacacgtttt
    23041 ttctctatat cttctattat tgtagctgct aactcttttg gatttgtatt tacagtaaat
    23101 gtagctccaa ctttatcttt taactcacta gttaatatat ccactgctct tgaagaacca
    23161 gctattggag gcattattcc taaataagtg tctataccag aagctacaac atagcatcct
    23221 atagcaactg ctttttctga catccattct ggagctatac ctacaactgg aaggtcacac
    23281 atatccatat ctaagtaatt agctgctgct ccaactaaat ctagtatacg acttatatca
    23341 acacaagaac ccatatgtag tactggtggg attcctacta atttacagac agttgcaaga
    23401 cctttacctg catatttttc agccgcatca gattccatta aaccaaactt agctgctgct
    23461 gaagctccac aacctgtagt aactactatt atgtcgtttt tgattaattc tttcattatt
    23521 gttacgtgag cctcatttga aactccttta gcattgttac atccaactac accagctgct
    23581 cctcttaata ctccagcttt tagacagtct gttaatggct taactgttcc tgctgggtct
    23641 atatgagagt ttacaactct gtctaattga tttactactg cttctacact atacccaact
    23701 gttgcgcctg attttaattc aggtataagt acttttgatt tatctctatt tttaaagttt
    23761 aaaatagctt ctttaactat tgctttagca tcatcaagtg cttgttcttc tctaaattca
    23821 atataagttg aacctgttat cttagctttt ggagaagttg ttacaaattt agtatggtaa
    23881 caatctgcaa ctctagctaa tgcagggaat atacattgaa cgtcaactat tacagcttca
    23941 actgctccag ttattattgc aagttcttgt tgatggaagt ctcctgctat ttttacacca
    24001 tgtctcattg taatctcatt acctgtacaa cacatacctg ctaagtttat tccatcagca
    24061 ccaacttctt tagctaaagc tactaagtct ggctcttctg atgctaaaac tatcatttct
    24121 gataatgctg gctcatgtcc atgtaatatt atgttaactt tattttcttc taatactgct
    24181 aaattagcct ctgttcttct tggcactgga gttccaaata agatatcgct tagacgagta
    24241 cctatcatag aaccacccca accatcagcc atagaagttc taagactcat gtgtattaaa
    24301 ctatctatat caccagtaca tcctatatga gtagagtgca ttattgttgc aatttctcta
    24361 tctatagctc ttggctctat agcgtattct ttccatattt tttgtcttgg ttctggtgca
    24421 ttttttataa atcttaatgt cccaaaaggt tttccaaatt ccattaatgc aatttctgcc
    24481 acttcatgtg ctacatcata gatatctcta ccttctgtct ctacatccca ttctttagct
    24541 aaagtaatta acttagcttc gtctcttatt ttatagtttc catttggatc agctaatgct
    24601 aatgtatgtg ctatatctct agcatggtct gaatgggcag ctgtcccacc agcaaccatt
    24661 cttgcaaagt ttctacctac tatagtatgc tcatctgctc cacataaccc ccttggagtc
    24721 ttagggctta ttctacatgg tcccattcca catattctac agcaaacacc ttgaagacca
    24781 aaaccacatt gtgccttaaa gccttctttt ctatcataca ttgtttctac gccttcttct
    24841 ctagctttag ctatcatctt ctggctgttt aaatcaattg ttaacatttt ttcatccata
    24901 ttcctatccc ctttttttga tttttaaaat cccccaggtg actgacttca tgtcataaaa
    24961 taataaaata aatgctttct aagttgatta tatactaatt ttcagtgctt tgctttagat
    25021 ttaaatattt ttttaacaaa attagataat acataaaaat tttattttct acacttaatt
    25081 taagttgatt ttatcgcttg tttttggcta tttgttaata tctaaaccta cttttttgat
    25141 acttcagttt aattaaatta tgttttgatt tttttaaatc aaatttgaaa tttttctagt
    25201 catttttata ttattgcaga ttgtttgtgt atttattatc tttcactact gtttggactt
    25261 attacagatt tttactccct aaacttaatt agtaaaaact tcttagaata gcattttttg
    25321 gactaatttt tttgaatttt tttatttttc ctactttaat attaattata gcttcaaatt
    25381 gaacatttgt atatattcat ttgaagctat aattattttt tatataaaac ttttttaata
    25441 cagcattaat ttagacattt tgactatttt ttctacttta attcatttat ttcaagcgat
    25501 ttatcctatt tcatattttt agctacaata gccccatatg caatagaata taatttagat
    25561 tcatgtgaat cagctcttga cactaaaact ataggagctt ttgcacccat aattatacct
    25621 gctgatttag agtctgccat atatgtaaag gctttcccta ttccattgcc aacctctatt
    25681 gttggaacca atatgatatc tacatctcca gatacttcac ttttaaaccc ttttatctca
    25741 ctagcttctt ttgaaacagc taaatcaaaa gccagaggac cttctacaat tacattttca
    25801 ccaaattctc cttctttaca agcttttgct aacatatctg catctacagt tgcttgcatc
    25861 ttaggattta ctttctcttt agctgccaaa catgcaactt ttacagtttc cattcctaaa
    25921 gcttttgcag cttttataga attttttaat atctttgcct tttgttcata atcaggagct
    25981 atattcatac ctccatctgt agttataagt aatttatggt atttttctaa ctcatatacc
    26041 ataacatgac ttaataaact atcagttcta agaccatagt ctttatttaa cacttctttt
    26101 aatatgacag atgtatctaa taatcctttc attacaaagt cggcttcttt acttgatact
    26161 aatttaactg ctatttctgc acactctttg atatcatcct tatccactat tttgatacca
    26221 cttaaatcaa atcctatttc ttttgatatt tctcttattt tgccttcatt tccaaccaat
    26281 ataggagtaa ttatatttct ttctacagca tcctttattg ccattaaaac ttctttatca
    26341 tgagctgctg ctacagagag tacaattttc tctcctccct taagttgttc taaaatatca
    26401 tctaattttt ttatcaaaag taacccctcc cttatatata tttaactaaa taataccata
    26461 tttgctatac cttttctcaa tttatttttt atgttataaa gaatttatat gactaaaaga
    26521 cagtttaata ttttattctg ggatttcatc aatagctctt aaaagctttg caggaacacc
    26581 acctacaata gtattttttg ttacaactgc tccagcagcg ataattgcat tatctccaat
    26641 agtaactcct ggaactcttc atacaaaaaa gaggcttatc tctattttga gatagcccca
    26701 cttaaccgat aaaattaaat acaacctaac aatatcctta cttatttatt ccaagttctc
    26761 ttagacaagc aatagtaatt tcatcttgtg gatttaattc ataagctctt tctatatagt
    26821 aagttgcatc atcaatatca ccattattta aataagccat tcctaaattg caaagtattt
    26881 ctgggtcttc ctttatctta gccgcttgtt caaaatactc tattgcttta tctaaattat
    26941 tcttataagc ctcacaaagc cccaattcca ctatagtatc cacctgatta ggctttatta
    27001 tcaatatctt ctcaagatac atcttagcct gctctatttc gcccataccc ttatatccaa
    27061 gtgctatcat aaacagcaag ttccaccaat ccatatgttc ttcttctaat ggaagtaact
    27121 tctctaatcc ttccttaaac ttaccttgga atacaagtgt atatccttct tcatattgaa
    27181 ctttaaagtc catcttgcct agattctctt gtacctcagc tactaaatca gcatctaacc
    27241 ctagccttaa tgcttcttcc caagtcagct tagtctttaa atattgacct tgattataat
    27301 aatggtagcc taagtgataa taacctaatg caaaattctc atcaacatca attacctttt
    27361 caagcttagc catggcttca agtaagaatg cattcattgc cttatcatcc atatcttttt
    27421 gatactgttt agctatctct tggcaaacaa tcgcatagtt atacattgca tctaaatcat
    27481 ctggatacat tgttataaat gcttttatat atattaaaga atctgtatgt tcaccaatct
    27541 caaagtattt tctcgacata tatcccatat acgatttcaa atccaaatca atatcttttg
    27601 ataaagcatt taaaaacttc tcatactctg cattgttttt aaacttacta tctattccaa
    27661 ttatatatat cattgcatct gctatagaca ttgaatttaa cttatcttga gcagtctttt
    27721 cttttatccc ttttactaat acctcatttt ttataggtac atctaatccg ccttttggca
    27781 ctttatagct ttttaattta aactctccac catgttttat agttataaaa gctaattctt
    27841 ctgctttttt tagcaaatat ttttctatct taaaatccat tttatcctcc taaatactta
    27901 aatctctact ttatgagttt tagatttctc aaatattttt ttatcatcat actcaaataa
    27961 gactacattt tctacttctc ttatttctgt atttatatca ttttttaaat ccacaacatt
    28021 aaatctaaat ggctcaaaat gaacatattt tattatatgt ttagctggtt tatcaacaaa
    28081 actaggtaaa tatgttgata agttatcatt atcttgtaaa aatacatggc atctattctt
    28141 aaaatcatcc acatctagct tattaaaaaa ctgtggtata tttgatgttt tacccagtga
    28201 tatatagtca tattttaata tatcattgaa tacatcatta tctatgttga ttttttcatt
    28261 atagaaatcc atcaatattt tatataactg attctttcct tgtgccaaat caaagtagcc
    28321 attttcatca aaatacttgg caaaaacctc aaagaattta aaaggacttt gtttataaaa
    28381 tctgcctata atatatctca tagataacac aaagttttta gaattgtagt atctctccag
    28441 tatatcttct atatccttta gcttcaaagt ttcttcatag cttatataat tattgtataa
    28501 aaactcatat ggagcataat ccttatattt aaaaccatgc tcatctgcaa cttttctcat
    28561 acctgtccct ttaatcatct ttaaaaagcc taattgcaga tgctctatac ctagattaaa
    28621 tacatcatta aaagaatttt caaagctctt ataatcttca taaggcagtc ctgcaattaa
    28681 gtctaagtgc tgatgtatat ttctataaga tgctacagtt tgtacaacat gagacaactt
    28741 tttaaaatca tcccttctac ctactgcatc aagtgttttt tcattcgttg actgaacccc
    28801 tatttcaaat tgaaaaagac cttctttaca atcagccaaa aactcaagca tcttatcatc
    28861 tatcaaatac gctgtaactt caaaatgata agttgtatat ccattatcat ttttcataag
    28921 gaaatccatg atttccatag ccacttttct atttgcattg aatgtcctat ctataaactt
    28981 tatctgtgat actcttgcat ctattaaagc ttttaaatca ctctttatcc tgtctaaact
    29041 aaaatacctt agacctggaa tagtagatga taaacagtac tggcagttaa aaggacaacc
    29101 tcttgatgat tcataataca ctattctatt ttcatattct tttggattca agttttcata
    29161 aggactagga atctcatcca aatcttgaag taattccata ggcttattca ctattatctc
    29221 attgccttgt ctatatacaa gtccatttac atcatttatt ttcatctttc cttgcaagtg
    29281 aagtactaag tctctaaaaa ttaattctcc ctctccataa agtatataat ccacaaaatc
    29341 atactttttc attgcctcat aactatcata actcacttcc ggtccgccca aagctatttt
    29401 agtattaggt ctaatttttt ttagattatc acaaagttta actatatctc ccacattcca
    29461 gatatatgtt gagaataata ttatatcata ttcattttta tatatatcct ttaaaatata
    29521 gtccaaatcg ttgtttatcg tgtattcttt catattaact tctatcaaat ctcttacaaa
    29581 ttcttttaga tatcttatag ccaaatttgt atgaataaac ttggaattta atgttgttaa
    29641 taaaattttc aaatatttct cacctctttt taagattata ctgtcttttt gtacccctta
    29701 taggttaaaa tagtatatgt aaagtctaaa taatatctat ataattaatt tattaatttc
    29761 aagtaatgtg aggaaaggaa gttttttatg gaattaattg aaaaagtatc tatcaactct
    29821 ttatcaaaaa gagatttact acttattata aagtctcttg aatacactaa tgaaaatact
    29881 caaattagtg atttcattga ccttaggaat aatatagtaa aggaattatg ttttttaact
    29941 gacactaagg aaaaagattt tttagattat ctagaaaaaa atagcacact ctaataacct
    30001 aaaccttttt aaactttaat atataaatac ctgatttaga atttattttt atgcttaata
    30061 tattatcatt aaaggttttc gacataactg ttatttgatt aaatataggg tctattatag
    30121 tattaccttc ttcaagtctt ataagacttc ttgggtctat gcttttatta tatgccttaa
    30181 ctccaatttt atattttctc aatttaacaa catattcgga catagaaaaa ataaaatcta
    30241 tattatcttc atttaattta ctatcttcac ccaaaatgga taatatagat ttttttatgc
    30301 tattaattcc ttcattttct acagttctat cttccatata tacatcatat agaacattta
    30361 aaacatttaa taaaatactt tcttcatcat aatcttcaga tttcaaatca atgtacttat
    30421 caattaattg tattgcttta atccttgcca tctgaaactt tacaacatct gatttgtcta
    30481 attctataga aaatcctatt atcttgtctt taatactctg tagtaattcg acatactcta
    30541 ttttactatt atttataaga ttgtgcataa tggaattata cactacagaa cctaataaat
    30601 aatcaaataa aagttcttct tttttaaaat aaataacata cttttttatt agtttaataa
    30661 cctcatcttc gcttttttga atattagtat ttgataaaat tagtggtagt aaaatattta
    30721 aaaaattgat atttcctatt ttttctccat aaaatctata gtaaataagt tcatctctca
    30781 gtctattttc gtctatatac acacatcttt gcgttttatc atctattaag gattttgtat
    30841 ttattatagt taaatcttta agagccctac ttgcactact aaaagaagat gtgtagactt
    30901 tttttagtaa ttcgtcattc ataaatatat cctttctgaa aaattgaatg taaataaatt
    30961 gttattaaaa aaaaagagac agcccgttta agaagctgtc atatataggg ggatagtagt
    31021 gtacaaaaat cattgtaatc tactatctat atattattat acgatactac ttttttatat
    31081 gtaaagcatc agttttcgac atccctatat tttacagtta tacaaattgc gtactaagtt
    31141 caattttatt ctttttattt caacatttta tcatgctaca ttctttccgg agcgtgcatt
    31201 cccaacaatt tcagagaatt ttctaaagtt tgttttgttg ctaaaactaa tgcaagtctt
    31261 gcttttctta tttccaaatt ttctactaaa attggattgt catgataaaa tttattaaac
    31321 gcttgagcta aatctaacat aaatctagtc actatatgtg gctcattttt ctttagagca
    31381 agtaaaatat tcttattgaa tgattctata actctaagaa cttctgcact atcttcatca
    31441 gctaatagac tataatctat atcagaagtc acttctactt ctgcttttct taaaactgca
    31501 cagcatctag catgtgtata ctgaacatat ggtccagtct caccatcaaa actaagcgtt
    31561 ctttcccaag agaaggtata gtctttaatt ctactgttag ataactcttg gaatactact
    31621 gccccaacac ctacttgctt agatatttca tccacatttt tagcatttgg atttttagct
    31681 agtataattt ccttagtttt atctatagct tgatttaaag catcttctaa aaatactact
    31741 cttccttttc tagtcgacat agtaccttct tcaagtgcaa ccataccaaa tccaacatga
    31801 attaaatctt ttgcccaatc atatcccata agctcaatta ccttaaacca ttgttggaaa
    31861 tgtaagtttt gttgagaacc aactacatat atacacttgt caaaatcata agtctctttt
    31921 ctatatattg cagcagctaa atctcttgtc atatataacg ttgaaccatc attcttagta
    31981 ataagtgctg gtggcatttt atactcttct aaatcaacaa ttcttgctcc tttagactct
    32041 tttaaaagat ttttctcttc taatagttcg ataactctgt tcattttatc agaataaaaa
    32101 ctctctcctg ctaaagaatc aaattctata tctaaaagtt tatacactct gttaaactct
    32161 tttaaactct catttctaaa ccattgccat aattcttgtg cttcttcgtc accattttct
    32221 aatttattaa accatgctct tgcttcatct tccatttctg ggtgttgttc agcttcatca
    32281 tggaatctta cgtataattt tagtaattct ggaattggat tagactctac tacttctttt
    32341 tctccccact ttttaaaggc cactattaac ttaccaaact gagttccata gtcacctaaa
    32401 tgatttattc ttatagtctt gtatccttgc gaatcatata tcttatataa agcattacct
    32461 ataactgtag ttcttatgtg ccctatatgg aaaggttttg ctatatttgg agaagaatat
    32521 tcaactatta cagttttatc ttttccaaaa tcactatgtc cgtaattttc tttttcatct
    32581 aaaacttttt taattacagt ttctgctaat tgagatttat ttacaaagaa atttacatat
    32641 ccgcctaatt gtattacttt tgttatctct ccacttggtt ctatactttc cgccaattca
    32701 cttgctatca tgtttggagc ttttctaaac actttggcta atttaaagca tggaaaagca
    32761 tagtccccca tatccttatt tggtggaact tctataagtg cctctatctc ttctttcgat
    32821 aaatcttcta ttttttcttt aaggcaattt gatattgcca ccttaaaatc ttgcattctg
    32881 ttgctcctct ctacattgtt cctggtttat attgtgctta tctctttatg ttaaatcaaa
    32941 tttcgtgttt tttcaagtat ttcattacag tgtaaaacac tttaataatt atgttttctg
    33001 tatatattaa aaatactata attgcagttt ttaatcacac tattattgat tttttataag
    33061 acttttttct attttattgt ttcttgtact atccagttga ctttatatac tttttttaat
    33121 cttttatcaa ttttcataca tcaatattaa ttttatatac atttattttg ctcttttatc
    33181 tatttttata catcaatatt agctttatat acttttttta ctcttttatc tatttttata
    33241 catcaatatt agctttatat acttttttta ctcttttatc tattttctat aaatcttttt
    33301 cactcttaat ttttattcct tcttcttcta acagccttgc tgttatacct ttccctggta
    33361 tctttttacc tgaaaaacta ccatcatata ttagattaca tccacaagag gggctaccct
    33421 cttttagtat tgcttcgcta catacatata aatttgctat ttttagagtt tcattagccc
    33481 ctcttacaaa gttttctgtt acatccttat tatctttagt aattactttt ccatcaacta
    33541 tctcagcagg tggtcttggt gtagatagac cacctaactg ctctgggcat acaagtgtaa
    33601 attctttgcc ttttaaatat tccttgactt tttcattttc attattatcg ccactatatt
    33661 tacaatttat tcctattaaa catgcagata ccaatatcat aaaaatgtgc tcctatacaa
    33721 attcttaata tattcttata caaattacta atgtattctt atacaaatta ttttaattta
    33781 acaattgtta ctcctgctcc accttctcca tattgaccac ctcgttgtga ttttacatgt
    33841 ctatttcttc ttaaaatgtc ttgtagccct gcttttaata ctcctgtgcc tattccatgt
    33901 attactgtta cagactctaa acctgccaca tatgcatcat caagatactt ttctacttcc
    33961 attatagctt cttctaggtt taaccctcta aggtcaactt cattttttac actaccagat
    34021 tttgacctta taatgtttct cgttgattta gttacatttg ttgaaacatc tttgcgtgtt
    34081 ttttgtaaag atttaaaagg tagagtcatc ttcattatac caatttgcac tactgcttct
    34141 tttctctttt tatctactga aactacacta ccattttgat ttaaagttat taccttaact
    34201 tcttcacctg gctttaagtc ttttatctcc ttatttgata cctttggaac tatcatactt
    34261 tttactgttg gctgaagact tcccatagag ctggtcaatt cttttctaag ttcttctatc
    34321 ttacgattct tttcttttga agctctttct tgttcaagat ttctaagttc ttttattata
    34381 atatctactt cttctttagc ttgtcttata attgaaaatg cttctgattt agctttttca
    34441 atcatcttat ctctttgact gaccaatttt tcaagttttt cgtcatactc tactttcagt
    34501 ttttcaatct cttcttttaa tctttcagct tcttctctat cttctactgc tttgattcta
    34561 ttcttttcaa cattctgtaa cacatcttct aaagctatgt tttctgtatt tatatattct
    34621 ttagcacgtg aaatcacata atcacttagc ccaagttttc tagaaatctc aaacgcattt
    34681 gattttccgg gaacacctat aagtaactta tatgttgggc ttaaagtttc tatatcaaat
    34741 tcaactgctg cattttctac acctggttta gtaagagcat aatttttaag ctcactatag
    34801 tgagtggtag ctatacattt agctcctaca gaatttatat cttctaatac tgctattgca
    34861 agggcagctc cttcaacagg gtctgttcct gctcctaact cgtcaaatat aactaaagag
    34921 tctgctgtta cgttttgtaa tatagatact atattcgtca tatgagatga aaatgttgat
    34981 agactctgtt caatactctg ttcatctcct atatctgcaa atacattatc atatacacac
    35041 atactacttc cataatcagc aggtatatga agtccacttt gtgtcataag tgcaaataga
    35101 cctacagttt ttattgtaac agtcttacca cctgtgtttg gacctgttat caccaatgta
    35161 tggaagtctc ttcctaaata aattgtattt gctactacct tctttttatc cagcagtgga
    35221 tgtcttccat tttttatgtt taaatattta tcctcattta aagttggttc tattcctctc
    35281 atctgtatag aaagttttcc ctttgaaaat gcaaagtcca atcttccaag tatctcttga
    35341 ttagagatta aatcttcgct cacttctcca accatagctg aaatctctga taaaattctt
    35401 tctatttcct cttgctctcc tagtttcaac tgcctcaatt cattgttcat ctctactata
    35461 gtcattggct ctataaaaag tgtcgcacca gaagatgact ggtcatgcac tataccagct
    35521 acttgcgacc tatattcaga ttttacaggt actacaaatc tatcacctct tagagaaatt
    35581 attgcatctt gtaagtactt ttgataagta gttgaactta ttattgaatt taattttgac
    35641 ctaatggatt gatttttttg ggctattctt cttctgatat ctctaagtgt acttgaagca
    35701 ttgtcagata tttctacttc actaattata gcattgtata tctggtcttc tatgtccttg
    35761 tacacatata gagaatttga tagagattgt attattggat aattaaaatc ttcttcatca
    35821 ctactagata agctatttct taatcttcta gccactctta aggtatctgc tatcataatc
    35881 agacttcctg ggtcaagaga agcacctata taagctctct ttaccttatc ttctatatca
    35941 tgaatacctt ccaaccctac tgaacctctc tttataataa ttgattgagc ttcactagtt
    36001 tcttctagca tagatttcac ttctacaaaa tcagtatttg gtactaaatt ttctatatat
    36061 tttagaccta aagaagatga ggctttcttc tttaacaaat ctattatttt attgtattct
    36121 agaactctta acgatttctc attcattttc tatattcacc atcctcgata ttttaacttt
    36181 tttatttaat tttaaaaatg tatgttttca agcatttcca ataaaaaatg caagttttat
    36241 ttctttttca tttctaaaat tattatattt tttctctttt agatatattt tacacatatt
    36301 ttgtattata ctatgtatgt agctatctat atattataca taaacatgct ttatttgtaa
    36361 tataatctgt taaaaaatct tctttaatat ttttaaagga gtttatttta gcttataaaa
    36421 aaatagctac ttatatagat aaattaagga ggaacatgag tcatgggaaa cgtattagaa
    36481 ggattaaaac cagaaagtgt ttttaaaaac tttgagaaaa tatctcaaat tcctagaggt
    36541 tctggaaatg aaaaaggcat aagtgatttt ttacttagct ttggtaaaaa tttaggtctt
    36601 gaaactattc aggatgaaag cttaaacata ataataagaa agcctgctac aaaaggatat
    36661 gaaaattgtc caggtgtagt tcttcaagga catatggata tggtttgcga aaaagaaaag
    36721 aatgttgaac atgattttct taaagaccct ataaaattaa gaattgatgg tgacatgata
    36781 tatgctactg gaactactct aggagctgac aatggtatag ctgttgctat gggtatggct
    36841 atattagaag ataatacttt agagcatcct gcactagaag ttttagttac tgttaatgaa
    36901 gaagatggta tgaatggtgc agatgcacta gaccctagct taattaaagg tcaatatatc
    36961 ctaaatatgg actccgagga ggaaggatac ttattagtta gctgtgctgg tggtaaaact
    37021 tgtgttgtta gtttacctgt tgaatacaag gaagttaaag gtgacaaaca aggattatta
    37081 gttgaggtta ctggactatt aggtggacac tctggtatgg aaattgtttt acaaagagca
    37141 aatgctaaca aagcaatagc tagagtatta agtgtattga atgttgatta tgaattagct
    37201 tctgttgatg gtggtactaa gcacaatgct atacctcgtg aagctaaatg tgtaatagct
    37261 gttaataaag ctgatgttga atctgctaaa aaacaaataa atgacatttt aactgcattt
    37321 aaacatgagt ttactacttc tgaccctggc atgacttact cagtagctga aacttctgta
    37381 gacaaagttc ttactaaaga ttgtaaagaa aaagttgttc aaatgtcttg cttaactcct
    37441 catggagttc aatcagtaag tcttgatata gaaggattag ttgaaagttc tactaacttc
    37501 gctataattg aaactaaaga atctactatt gaatttttaa cttctgttag aagttctgtt
    37561 atgtctatta gagatgaaat cgctgataga ataagacttt tggctcaagc tttaggtgct
    37621 aattacgacc ttatagctca atacccagct tgggaattta aaaaaggctc aaaattagaa
    37681 aaaatatgca gtgaaactta tgagaaatta actggtaaag ttcctactgt tatggctcta
    37741 catgctggtc ttgagtgtgg attattactt gataaacttc ctcatgctga agctatctct
    37801 ataggaccag atatgtttga tgttcatact ccaaatgaac atgttagtat cccttctgta
    37861 gctaatgttt gggattatgt tattgaaata ttaaaatcta tgaaccaata ttaaatttaa
    37921 gttttgattc taaatagatt ttaattttaa gtaatctata taaaattaac tctgtaaatt
    37981 aatactactg ttagtataat atttactttc aatattaact tatagaaata aagcctaatg
    38041 atagataata acatgtatca ttaggcttta ttgtaattta aatattatta aactttattc
    38101 tgttttaaaa ttaattctta tactatttta aatctatttc ttccttgtct cttagaatca
    38161 taaagagcat tatctgctat ttgatacagt tcatcatact cttgaccacg ctttgttata
    38221 actaccccca tactaataga taaactttct ccatttggca acttaatgag atgaatatga
    38281 ttgtatacat cattacattt attgataagt tcttccttat ttattatatc atttatataa
    38341 acactaaatt catctccacc taaacgacct actatatcat cttttgcaaa actttcatca
    38401 agtacctttg caacatcaat cagtacttta tctcctacca ggtgaccata agtatcatta
    38461 attgacttaa aataatcaat atctataatc aataaagctc catttttttc agttgataaa
    38521 tttaataaat tttgtgtagt taattttcta atatatgctg cattataaat atttgttaaa
    38581 ctatcccttt gaactttatc caacaatcta ttcttttcct ctttttcaga atcaatatta
    38641 gctattttac caattacata cattggtatt tttctatcat tataaattat ttttgaagta
    38701 attctaatcc aatgaaaagt atcatcaagc atgatagaat acatttcagt agtcccattt
    38761 tcttgtgatt ttattacatc aaaaaacttt ttattatatt ctcttcttat tttatctctt
    38821 tcattttcta tattgccatt ttcactttcc ttatcacttt tatccaaacc ataataagtc
    38881 tcaataccct tttctggcat agaaattatc aatttatctt gcttataatc atactcaaaa
    38941 aagtattcac ttgtcatttc atacaactga gtatgttttt tgagttccaa agatatcttt
    39001 tcgttcatac ttgtacgagt atgtaaacca aatgccataa atccaataat acaaattaat
    39061 aaacttgcta caataaaaat agtctcaatt ggattctgtt gcataatata aagcaacgag
    39121 aaatcttgtc tatatgtagt attttggtag acaattgatt gcattttttc tgatgaaata
    39181 cttataatag ctttattaaa tatattcaat aattcttgtt tatctttttt aattatgcca
    39241 aaacaaatac tctttgcttc ataagtttga ggaactaggc gcacattttt atacttaggt
    39301 tgattcatat agtactgcat agaataacct tctccataag tgtaatctgc atagccttta
    39361 ttaacagctt ctatacactc ttctaaatta tcataccaaa ctatattttc ttcaaactga
    39421 ccataataat caataccttt ggctagagct atacgctttc catttagact attctcattt
    39481 aatttattat taatcatcat agtatattga gtagaaagaa aaggccgaga catagctata
    39541 ttatgttcac gagagtactc ataatcataa atcattcctg ctacaatatc aatttcatgt
    39601 tttttagcca tatcttccaa atcttcttga gattttacag gcacaagttc aaattccaaa
    39661 cctgttttat cacatatatg atttaacaaa tcaattgata tacctcttaa ttctcctgta
    39721 tctttatctg cattttgaaa cggtggtttg tttaaaagta ctcctacttt taatttttct
    39781 gtatctttaa tgtaattagt ttcttcatca gataaaaaca tttgattatt ctctggcgta
    39841 aagtatttct catataaagt agttgaaaaa tatgggtcct tctgttcaat attattaatt
    39901 gctgaattaa gcttttgagt taagtctgta ctgccttttg gagtaatgaa ataaaatggc
    39961 tttgatgaga attttgctac agtacgcaca ccttctattg ggttcatact aacattaaga
    40021 agtacatctg ctttaccact ctttagtact tctaattgct cgtcacttgt tttacaatat
    40081 accaattcag gtgacataag attcatttta caatactcat ctaattcttt aagcctagta
    40141 tcagaatttt ctattacagc aatacgaatt tttttcacat cttgcgaact cattatgtta
    40201 tcaatatctg tattttcata taatgcttgt agtactgtat ttgctactcc ataactgttt
    40261 cccgcataat tatatatttt ttgcattggc tcattgtata acatacctcc cattatatca
    40321 atttcaccat tttctaacat cttcattaat tttgtaatag attcatttat ctctccagga
    40381 acttgaacaa attcataatt ccatccagta tactgtgcaa tttctagcaa atattcatat
    40441 gtatacccaa aatagttacc ttgctcatct atttcagtta aacctttttg aataggataa
    40501 gcaacacgaa tggtacgatt atcattacct atagcattga taccaaaaga aaatatgcaa
    40561 gaagtgaata tagatgtaat tacaataatt aataaaagta atttttttaa attcactaca
    40621 caatcctcca tatagttaag atttacagta taaattactg cataaacttg tagacatgaa
    40681 aaaatagatt agtatataaa aggatatata aatctactta gaaatttaaa tatccttaat
    40741 atatacaata tatttaaatt ataactcatt tatatatcta ttacaacaaa tttaccctgc
    40801 taaataccta ctctatatcc cataatttta caagttgtaa tgaagtttaa gttctatctc
    40861 atttcaaatt tagcagtgtt tctatttaca gttcttttat atttcacatc tggataaccc
    40921 aatataaatg aagtgataac tgcttcgttc tcgctcattc ctaacagttc ttttatcttt
    40981 ggctctacat ttgatgccat aacaaaaaat ccattataac aaattcctaa tccttgagaa
    41041 taggccataa gttccatatt agatgcagcc aatcctccat ctacataagc acttccacct
    41101 agagacatat cacctacaac tatcataagt agtggggcat cataaaataa agaatcattt
    41161 ccgttctctt tatatctttt gtacattttc ttaaatgtat ttttatagat agaacgtaca
    41221 gggtcattgt catcagtatc taatgccaaa ttataaagac cttgtattgc cagttctttc
    41281 acttctttta gcttttcttt tactaatatg tatcttatag gctgtctatt accacctgtt
    41341 ggtgtgtatc taccagcttc cactatgttt tttatttttt cttcttctac ctctatatct
    41401 ttatattgtc ttatacttct tctaaattta ataaaattca ataacttttc gggttctaat
    41461 tcaaaacttt cacgattgta ttctattact tcatttttat caaatccttg catttctatt
    41521 gcatctgttg ggcaaattgc catacagtga ccacagttaa tacagagaat atttttaacc
    41581 tttgctttat catccttaac ttttattgca tttacaagac agtctgattc acacatccca
    41641 cagcctacac atttttctaa atttatgtct atcattccaa attattcctc cttttaaaaa
    41701 atttacttta gtataaaaca aatagttgtc taagtcaatt tttatttttt taacaatata
    41761 ctagccttaa ctacacttta atggagaaaa atatacataa aattagaact taaattagaa
    41821 tttattcaaa ataaaagata aaagaagtaa atgtctaaaa gtgaactttt tagttaatga
    41881 gacattcttt attgtatgaa atcaagtgga tatttatcat ttcaacaata aaaaaggctt
    41941 acctctattt tggatatgtc cttgttaagt agacagacta aaaaaggcta tctttatgca
    42001 ctgagatagc cccttttccc aactactatt gtttatttta atattatatc aataaattta
    42061 atttgctata acctgtaagt tacattttaa tttgatgtaa ctttaaatta catttttaag
    42121 taatatcttt aaattatatt cttaaaatat atcattaaac tacattttaa ttaatctaaa
    42181 aactatatct taattaatct aagaaactta cattataatc ttttagtttc ccattatcat
    42241 atacaatctt tgcactaaag atatttccag tcttagccca atttaagaac aacctgtcac
    42301 cttcccacat atttaaatcg aatattttat cattaccaac ccaaattaaa tttccttctt
    42361 tacaatcatt taaatctttt tcagacaatt caccttcaaa ctcatctgag aaatacaaaa
    42421 acatatacca atcttcttca tctttaaatt ttggaaaagt tatcaaccct ttatatgaca
    42481 atgatttaag agtaagacca gtctcttcct ttacttccct aattacacat tcttctggag
    42541 tctctccttg ctcaaacttt cctccaactc ctacatactt accttcatgt atatcatctt
    42601 tctttttatt tctgtacaac atcaaagtct tgtcatcttt ttctatataa caaatagttg
    42661 taagtttcat gtatctcgcc ttactttctc tttatattct caattaatta ttttcagcac
    42721 tttcaagcac atcacttata ttcttcattg cattaagaga aagttctgca aattcatcaa
    42781 atggaatccc tatatcttct atacttctca ttgcatctct atttacattt gaagcaaatc
    42841 tcgtttcttt cattctttta ataacagact tagtctttac actagtaagt tttttatctg
    42901 gataaactaa agctatagca gttataaacc cagttatagg gtctgctgca tatattgctt
    42961 tttccattaa gctagttctt gtaactccca ttccatcatg atgaccaagt attgctctat
    43021 acatttcttc gtcaccgaag ttttcttttt taagcagttc tactgttgtt gtagcatgtc
    43081 cttcacatat ttctcctggc tttcttccaa ctatatctga atccaaatca tgtaaaagac
    43141 ctgccactgc ccactcttct tctttttctg gctctagtct tttggctaat tctctcataa
    43201 cagcttcaac agcataacaa tgttttctca ttctatcagt ttctaaatac ttaaataaaa
    43261 tttctaaagc ttcttctctc attttcacca atccccctgt tttttcacat atatgatatt
    43321 tttatatatt aatacacata aattcaagtc tttatatata ttcatgtata tttttcatgt
    43381 tatatctatt ctacaccttt atagtagtgt cctgcaactg ttccaatttc atctaatttc
    43441 ttatacaaat ctgtagcctt ttttccaagt ttataattat tactcaatac ctcaatgtga
    43501 gcttcaataa cctttttaac catctcacta tcttcaactg taaaatctat cctaaataca
    43561 tctattccaa tttcctctaa ctcatataga ttgtccaaca tacaagtaac cttcgaattg
    43621 taaattgtac ttctacagaa tatatcttgt gttatcctat aacttgcatc cgtaaagtct
    43681 cttaaagcat aactactttc cttacattta gcaactctct tgtccttttt acaatctcta
    43741 acaactactc ccataggaca gtattctgta accatcatag gagcatatcc atatattact
    43801 gcttcaattt ctacatctgt atattttaaa gtttgtttaa tttcatttaa gtttagttct
    43861 tgtgacaaac aaactgtact tgctccctct tctttgaagt ggtttatact ttcactattg
    43921 aatgcattta agtagcaatc tatatttaag tcttttttct taaagtattc catagagccc
    43981 cagttaccaa tttgaacctt attaattcct tttatattat ccaatatctc aaattgcttg
    44041 tactctttat ttctaacaat ccttggtgct gaatagatta attttttgtc agtgactgct
    44101 gtattatagt ggttcttatt caaagtatct attttacttg tatttgacaa agtatctatg
    44161 ttatttgtat ttgaacccat tagttcttta ggaataccta aagacgaaga agtatctaaa
    44221 tccatagaaa tacttgaatc tatagaaata cttgaatcta tagaaatact tgaatctata
    44281 gaaatacttg aggccatttg taaagctttt gataatgtat ttatatcttc ataatagatt
    44341 aaatctacat tataatttaa tactgcttct aattgctcca agttcttaac tttaactcta
    44401 atcttaggaa ctgtatcaag ttttttctgt ttatttactc tatttggttg gtattttaat
    44461 ctattcttct taaattttct atcttttatc tttattcttt cttcatctaa aagctcaata
    44521 caatcccttc tcatttgatt taacacactt ataggcatac ttacaccttc atccaggtca
    44581 atttctatct cttttaactt atatggtgta tttccaagct tttgaatttg tgtttctatt
    44641 ttttctttac ttaaagccac ctttatagct ttttcaacta ttttgtctcc ttctaccacc
    44701 gatttatttc cacaaaaatc acttataaaa agctctggct ttttacctag tttaatactc
    44761 acttttgcac gtatattagt ttttatgaac tctttatctt gctgaaatgt agcttgtact
    44821 ctattcatta attcgctgtc agaagtctta tatataagct gatttctctt tgcttctcca
    44881 acaaaatcta attctatcaa atccccttta tgtgctattg tagttatctc tccatccttt
    44941 attattcttc caatagtacc tccacctaag ttaattccat cacctttctt aagcgtattt
    45001 tctagcatta ctctaagtct tttgttcttt ctattataat ctaaaacttt tccaatatat
    45061 agcccttgat tattaggtct attagagttc attatatcct taccaacttc acctaatata
    45121 tatccttttg taaactttct attaaatatg gtatacaaat tatttattat ttcctcagaa
    45181 atacttattt ttttcttatc tacaaattca ttaatcgctt ctctatatcc tgaaaccaca
    45241 gtagctacat actctggttt tttcattctc ccttcaattt ttaaagataa tacacctgtt
    45301 tcaattattt tatccaaatc ttctatagta cttaaatctc taggactcaa caaataatct
    45361 ccattacttt ttactacttc tcctgtattt atatctatca actcatactt ttgtctacat
    45421 ggctgtgcac acctacctct atttccagac ctattgccta tcatactact cataaggcat
    45481 tgacccgagt aacatacaca taaagctcca tgtacaaaaa cttctatatc tacagttgta
    45541 ttttcacaaa tccattttat ctcatcaaca tttaattctc ttgctaaaac aactctatca
    45601 aaccctacac tctgaaggta ttttacatct tctaaggaat gtgctaccat ttgagtgctt
    45661 gcatgtagtt caaagtcagg taatagtttt tttataagtc ttgccattcc tatatcctgt
    45721 actattaaag catcaatatc tatatcgtat aaaaatttta catactctac aaaatcttct
    45781 atttcatact gttttatcaa tgtatttaca gtaacaaaga cttgcactcc ccttatatga
    45841 gagtatttaa cagcctcaat cagctcattt ctatcaaagt tatttgcaga tgctctagca
    45901 ctaaagtctt taccacctaa atacacagca tttgctccgt tttgaactgc tgcttttaat
    45961 gaatcaaaag agcctactgg tgcaagtaat tctatttttt tcatattttt ctcctctatt
    46021 tatacttgtt aggttaatat aattatatct ataacttaaa tatttgtatt aaatttatat
    46081 atttcttact atattttaaa ttct
//
LOCUS       DAMJYN010000026        45979 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.026, whole genome shotgun sequence.
ACCESSION   DAMJYN010000026 DAMJYN010000000
VERSION     DAMJYN010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 45979)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45979)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45979
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.026"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(72..275)
                     /locus_tag="PC466_001534"
                     /pseudo
     CDS             complement(72..275)
                     /locus_tag="PC466_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860778.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase"
     gene            complement(275..604)
                     /locus_tag="PC466_001535"
     CDS             complement(275..604)
                     /locus_tag="PC466_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1904 domain-containing protein"
                     /protein_id="HDF2768923.1"
                     /translation="MPQIKIRGINENDICKISKKMINDLVEAVKCPRDYFEIECIKSV
                     AIRDGKIADVYPFVEVAWFDRGQEVQDIVARIITDSIRNNLDVESMDLAFTVFEKEKY
                     YENGEHF"
     gene            934..1860
                     /gene="fba"
                     /locus_tag="PC466_001536"
     CDS             934..1860
                     /gene="fba"
                     /locus_tag="PC466_001536"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-1,6-bisphosphate aldolase"
                     /protein_id="HDF2768924.1"
                     /translation="MALITTKEMFKKAYEGGFAIGAFNISDLEQLQGVLKAAKAKNSY
                     VMIQASMSAVKYAGPHTLVEMVKAASDEIGVDVALHLDHGPNMDAIKTCIDAGFSSVM
                     IDGSHFDFEENVRITKEAVEYAHSKGVVVEAELGVLAGTEDDVTSDVHKYTQPAEAVE
                     FVERTGVDSLAIAIGTSHGAFKFKGEAKLRFDILEEIQSKLPGFPIVLHGASAVDQNA
                     VATCNEFGGNIAGAKGVPVDMLRKASSMAVCKINMDTDLRLAMTAAIRKFLAENPKEF
                     DPRKYIGAGRDAIQAVVESKIDDVLGSANSIN"
     gene            complement(1995..3626)
                     /locus_tag="PC466_001537"
     CDS             complement(1995..3626)
                     /locus_tag="PC466_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2768925.1"
                     /translation="MDNNLIGLIEHVENPAILCKESGEIIYCNHLIDSIFSFLDIKKP
                     RNINELDSNFDKTEILTDSKKKIAFRELRMTAHIYNMKDNNNENNIVYLFEKSLISDK
                     VIEDIIEHIDEVVVVFNKDGVIEKMNTVSDEILPFKRTEVLGRNITDLVRQGLVEEPI
                     ILNMLKVKKKIYRNIVYPDGKLIAYTAVPRWDSKGKLTGGVLTGRDISRVIKLESQIK
                     YSDISEDTEYISQSKIMDNIKKVVKRAAASDSSIFINGESGVGKEIIARTIYKYSSRR
                     DKPFIAINCGAIPNELLESEFFGYEEGSFTGAKKKGKKGLFEEANGGTIFLDEIGELP
                     MQMQKKLLRVIQENTITRIGGSKPIKIDVRYISATNISHEDLRNNLKFRQDLYYRLSV
                     IPVKIPPLRERKEDIVPLVNYFLKLYNEKYNREVEVSPKVIELLEEYSWPGNIRELKN
                     IIERFVVLSAKNVIGEDEFNMLINLDMIDNETDDLSPIVVNGIMNLNDAYKIVDQIMI
                     SKAINKYGSITKAAEVIGIYPSTIHRKIKSGHIHV"
     gene            complement(4109..5146)
                     /locus_tag="PC466_001538"
     CDS             complement(4109..5146)
                     /locus_tag="PC466_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HDF2768926.1"
                     /translation="MNDIKDLSSYKNVWIFAEQREGKIAPVVIELLGEGRKLAKEVDA
                     ELCAILLGKDVDGLAKELITFGADKVYVADDALLEKYTTDAYTKVIKDAIDEIKPEIM
                     LFGATHIGRDLAPRIASRVGTGLTADCTKLEIDPEDKKIKQTRPAFGGNIMATIICPN
                     HRPQMSTVRPGVMDKAEKDETRTGEVIALDYKITQDDIRTTVLETVKTKKDLVSLTDA
                     NVIVSGGLGLGGPEGFEMLKKLADKLGGVVGSSRAAVDAGWIDHSHQVGQTGTTVKPN
                     LYIACGISGAIQHLAGMQSSDFIIAINKNPAAPILEIADYGVVGDLHEIVPMLIEKLD
                     SVDDLLEAIKA"
     gene            complement(5165..5950)
                     /locus_tag="PC466_001539"
     CDS             complement(5165..5950)
                     /locus_tag="PC466_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012703997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HDF2768927.1"
                     /translation="MKILVCVKQVPDTNEVRINKETGTLIRDGVPSILNPDDANALEE
                     ALKIKDEHDDVTITVITMGPPQADFMLRECLAMGADDAILLSDRAFGGADTWATSNTI
                     AAGISKVGDYDIIFAGRQAIDGDTAQVGPQIAEKLDIPQVTYVQDFKIEGKDIIVQRQ
                     LEDGYELIKVSTPVLLTAVKELNTPRYMSVDKIVKAYKHDVKVWTIDDLDVNKEEVGL
                     KASPTKVFRSFTPEPRGKGEILEGKADEIASKIIIGLKQKHII"
     gene            complement(5983..7116)
                     /locus_tag="PC466_001540"
     CDS             complement(5983..7116)
                     /locus_tag="PC466_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003483287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="HDF2768928.1"
                     /translation="MLYNKEQELLRKAVRDFVSKELDTLPAEMDKTGVMPKELIKKLA
                     DAKFISSNIPEEYGGGGAGYVSYAIVMEEIARRCASTATFVTAGSSLASLPILYNGTE
                     EQKQKYLKGIATGELIGAFGLTEPGAGSDAGGQQTTAELVGDHYILNGRKTFITNGPF
                     CDVAIVIAVTDRSKGLRGTSAFIVESKWDGFSTGAHEDKMGIRGTETSDLIFENVKVP
                     KENLLGKEGQGFKIAMGTLEVGRIGVAALALGIAQGALDEAVKYTKQRVQFGKPIAKF
                     QNTQFTIADMETKVCAARGLVYDAAQKRDAGMRVAQESAMAKYYASEIANEVAYKALQ
                     LHGGYGFIKDYEIERMYRDARIVSIYEGTSEVQKMVISSNVLK"
     gene            complement(7164..8291)
                     /gene="hadC"
                     /locus_tag="PC466_001541"
     CDS             complement(7164..8291)
                     /gene="hadC"
                     /locus_tag="PC466_001541"
                     /EC_number="4.2.1.157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(R)-2-hydroxyisocaproyl-CoA dehydratase subunit
                     beta"
                     /protein_id="HDF2768929.1"
                     /translation="MEAILSKMKEVVENPNAAVKKYKNETGKKAIGCFPVYCPEEIIH
                     AAGMLPVGIWGGQTELDLAKQYFPAFACSIMQSCLEYGLKGAYDELSGVIIPGMCDTL
                     ICLGQNWKSAVPHIKYISLVHPQNRKLEAGVKYLISEYKGVKRELEEICGYEIEEAKI
                     HESIEVYNEHRKTMRDFVEVAYKHSNTIKPSIRSLVIKSGFFMRKEEHTELVKDLIAK
                     LNAMPEEVCSGKKVLLTGILADSKDILDILEDNNISVVADDLAQETRQFRTDVPAGDD
                     ALERLARQWSNIEGCSLAYDPKKKRGSLIVDEVKKKDIDGVIFCMMKFCDPEEYDYPL
                     VRKDIEDSGIPTLYVEIDQQTQNNEQARTRIQTFAEMMSLA"
     gene            complement(8291..9517)
                     /gene="hadB"
                     /locus_tag="PC466_001542"
     CDS             complement(8291..9517)
                     /gene="hadB"
                     /locus_tag="PC466_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(R)-2-hydroxyisocaproyl-CoA dehydratase subunit
                     HadB"
                     /protein_id="HDF2768930.1"
                     /translation="MSEKKEARVVINDLLAEQYANAFKAKEEGRPVGWSTSVFPQELA
                     EVFDLNVLYPENQAAGVAAKKGSLELCEIAESKGYSIDLCAYARTNFGLLENGGCEAL
                     DMPAPDFLLCCNNICNQVIKWYENISRELDIPLIMIDTTFNNEDEVTQSRIDYIKAQF
                     EEAIKQLEIISGKKFDPKKFEEVMKISAENGRLWKYSMSLPADSSPSPMNGFDLFTYM
                     AVIVCARGKKETTEAFKLLIEELEDNMKTGKSSFRGEEKYRIMMEGIPCWPYIGYKMK
                     TLAKFGVNMTGSVYPHAWALQYEVNDLDGMAVAYSTMFNNVNLDRMTKYRVDSLVEGK
                     CDGAFYHMNRSCKLMSLIQYEMQRRAAEETGLPYAGFDGDQADPRAFTNAQFETRIQG
                     LVEVMEERKKLNRGEI"
     gene            complement(9532..10332)
                     /gene="hadI"
                     /locus_tag="PC466_001543"
     CDS             complement(9532..10332)
                     /gene="hadI"
                     /locus_tag="PC466_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyisocaproyl-CoA dehydratase activator
                     HadI"
                     /protein_id="HDF2768931.1"
                     /translation="MYTMGLDIGSTASKGVILKNGEDIVASETISSGTGTTGPSRVLE
                     KLYGKTGLAREDIKKVVVTGYGRMNYSDADKQISELSCHARGVNFIIPETRTIIDIGG
                     QDAKVLKLDNNGRLLNFLMNDKCAAGTGRFLDVMAKIIEVDVSELGSISMNSQNEVSI
                     SSTCTVFAESEVISHLSENAKIEDIVAGIHTSVAKRVSSLVKRIGVQRNVVMVGGVAR
                     NSGIVRAMAREINTEIIVPDIPQLTGALGAALYAFDEAKESQKEVKNI"
     gene            complement(10371..11570)
                     /gene="hadA"
                     /locus_tag="PC466_001544"
     CDS             complement(10371..11570)
                     /gene="hadA"
                     /locus_tag="PC466_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isocaprenoyl-CoA:2-hydroxyisocaproate
                     CoA-transferase HadA"
                     /protein_id="HDF2768932.1"
                     /translation="MLLEGVKVVELSSFIAAPCCAKMLGDWGAEVIKIEPIEGDGIRV
                     MGGTFKSPASDDENPMFELENGNKKGVSINVKSKEGVEILHKLLSEADIFVTNVRVQA
                     LEKMGIAYDQIKDKYPGLIFSQILGYGEKGPLKDKPGFDYTAYFARGGVSQSVMEKGT
                     SPANTAAGFGDHYAGLALAAGSLAALHKKAQTGKGERVTVSLFHTAIYGMGTMITTAQ
                     YGNEMPLSRENPNSPLMTTYKCKDGRWIQLALIQYNKWLGKFCKVINREYILEDDRYN
                     NIDSMVNHVEDLVKIVGEAMLEKTLDEWSALLEEADLPFEKIQSCEDLLDDEQAWAND
                     FLFKKTYDSGNTGVLVNTPVMFRNEGIKEYTPAPKVGQHTVEVLKSLGYDEEKINNFK
                     DSKVVRY"
     gene            12247..13245
                     /locus_tag="PC466_001545"
     CDS             12247..13245
                     /locus_tag="PC466_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-2-hydroxyacid dehydrogenase"
                     /protein_id="HDF2768933.1"
                     /translation="MKILVFGARDYEEPVIKKWSEEHKDVQVDIYPENMTEENVVKAK
                     GYDGISIQQTNYIDNPYIYETLKDAGVKVIASRTAGVDMIHFDLVNENGLIVTNVPSY
                     SPNAIAELAVTQAMNLLRKTPLVKKKVCEGDYRWIAELLGTEVRSITVGVIGTGKIGA
                     TSAKLFKGLGANVIAFDQYPNSDLNDILTYKDSLEDLLKEADLITLHTPLLEGTKHMI
                     NKDTLAIMKDGAYIVNTGRGGLINTGDLIEALESGKIRAAALDTFETEGLFLNKKMNP
                     GELTDPEINKLLSMEQVIFTHHLGFFTSTAIENIVYSSLSSAVEVIKTGTATNRVN"
     gene            13607..14134
                     /locus_tag="PC466_001546"
     CDS             13607..14134
                     /locus_tag="PC466_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04002 family protein"
                     /protein_id="HDF2768934.1"
                     /translation="MEKMNKVTSKKTTYIVTSALFASIICLTIAYILHIPVGGNNGYV
                     HIGDAFIYLAATILPTNYAIAASAIGAGLADLSTGAAIWVIPTIIIKPILVLFFTSKS
                     DKIINKRNIVASVVAGIVGLVLYMFAEGIIIGSFTSAFVMSLLGLLQPIGSFIVFIIL
                     GMALDKLDFKKRYFN"
     gene            14161..14757
                     /locus_tag="PC466_001547"
     CDS             14161..14757
                     /locus_tag="PC466_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04100 family radical SAM protein"
                     /protein_id="HDF2768935.1"
                     /translation="MNILYTIENSIYVNITNTCPCSCVFCIRNEKDEVANSGSLWLEH
                     EPSVDEVKEAFNKYNLDDYDEIVFCGYGEPLMRINELIEVAKFIKEKSSIKIRINTNG
                     LSDLIHNKKTAILLKDVIDTVSISLNAPNKEAYNRVTQPKFGEKSFDYMLGFARDCKK
                     YIKEVAFSVVDEISPEEIEESKQLAKKLDIPLRVRHKN"
     gene            complement(14822..16405)
                     /gene="asnB"
                     /locus_tag="PC466_001548"
     CDS             complement(14822..16405)
                     /gene="asnB"
                     /locus_tag="PC466_001548"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HDF2768936.1"
                     /translation="MINLEEKYLTRKDTYMIKILEYNGHIRNWKVLCEELGIDSSLCR
                     DERERAILVEAYKTWGYDMANHMHGMFAFALWDTVEKKLFCLRDQFGVKPFYYYETEN
                     GKLLYGSSIRKIMEQPGFVKELNEDMLQIYMSFTYVAGENTFFRGVKKLMPGHYLVYQ
                     NKTVCIGRYWKPEFHPDHSKSIEEWTDEIHTTLQKIMPEVKSENETAELFLSGGVDSS
                     YILAMSDIEKTGSCGYEEERFDESKLAQQTANILGCKNSRYIITPEEYFASVPYVMYH
                     MEQPTGDASAIVFAIGCKAAAENTNICYSGEGADEFFGGYNIYHKAECYGENLKTFYI
                     GNTNIMNEGEKRKILKKYNPDVLPIEVVKGIYEETEELDTLTNMSNVDIQIWLEGDIY
                     FNIDKMSTAVGLEVRMPLTDTRIFDIASRIPSEYKVKGKENKIAFRTAASKTLPEEIA
                     FRNKLGFIVPIRIWMADDQYNKDIRDKFNSEIADKFFNIDEINEIFNDYISGNSDNWR
                     KIWMIYTFLVWYEIYFVKC"
     gene            complement(16470..16607)
                     /locus_tag="PC466_001549"
     CDS             complement(16470..16607)
                     /locus_tag="PC466_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768937.1"
                     /translation="MKNKKFNVITLIILDNHIYAINKEQISTNSKRIYFEKSRFFSDY
                     K"
     gene            complement(16971..17807)
                     /locus_tag="PC466_001550"
     CDS             complement(16971..17807)
                     /locus_tag="PC466_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDF2768938.1"
                     /translation="MNYIIKKVLNSSVVLVHDAKYNEFILLGKGIGYGKKTGEYICGS
                     NDNQMFVPVENTKSKKFLELMDDIPVDILKITQEIIVEAEKLLNSSFNKNLYLILADH
                     FNFAIERMRKGIKITNRVFWEIKNYYPNEFKVGMVAIYMVEERLGIQLPEEEAANIAF
                     HFANAMASDGNSYDTIKYAKVIGEIINIFVFSLNRTLDKKSMHYMRFITHIKFFVERF
                     FSDSMLSSGDDLLFNQMKRSNPKEMLIALKVRDFLEKKYGKKLTNEEIAFLVVHIARV
                     KQ"
     gene            complement(17831..19297)
                     /locus_tag="PC466_001551"
     CDS             complement(17831..19297)
                     /locus_tag="PC466_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000110363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HDF2768939.1"
                     /translation="MRKFPEGFLWGGATAANQFEGGWNLGGKGWSVSDVAKAHFDADV
                     KDYKSNNEITTKDIEEGLAHPEDEVNYPKRHGSDFYHHYKEDIALMAEMGFKTYRMSI
                     AWSRIFPNGDDKEPNEEGLQFYDDVFDELISYGIEPLVTMSHYEPPLNIVLNYDGWYS
                     RQVINMFVRYVETICERYKNKVKYWLTFNEVDSMIRHPYTTGGLVRDRFKDKNFEEVI
                     FQAMHHQFVASALATKICHEIIPNSKVGCMLTKLTYYPYTCRPEDVLATQQKMRSIYA
                     YSDTQVFGEYPVYLLSYFKNNNIQIAKEEHDDEIMKKYPVDFISFSYYMSSCEAADTT
                     GLDITPGNTLLAVKNPYLEMSEWGWQIDSIGLRISLIELYDRYRKPLFIVENGLGAKD
                     ILTEDKKVHDQYRINYLKEHFKCMLDAIIEDGVELWGYTSWGCIDLVSESTKQMSKRY
                     GYIYVDADDYGKGTYNRYKKDSFYWYKKVIENNSIDFK"
     gene            complement(19300..21162)
                     /locus_tag="PC466_001552"
     CDS             complement(19300..21162)
                     /locus_tag="PC466_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF2768940.1"
                     /translation="MNYKKTAIDIIEQVGGSKNILALEHCSTRLRFKLIDRSKVNQDA
                     LKKVQGVMSIVNGAQFQVVIGNSVVDVYDEILKVCPLDTNDSTVKTEEKINLGTRFIE
                     FIINIFQPLIFAIAGAGILKSLLMLLAMFNILKSDSTIYTLLVAISDATFYFLPLMVA
                     VTTANVLKCNRLVAIAAVGYLLLPATTTALSEGVELFGFTIPNIAYNAQVFPAILCVS
                     FLATMEKIFNKYSPKPIRTFFVPMMSLAITVPITLTILGPLGYNVGTIFTTIILFLYN
                     KMGFLVVGLLAAFLPFMVATGMHKALIPYSINTIGKLGYEALYMTSSLAHNISESGAC
                     FAVALRTKDETLKQTALSAGISALMGITEPALYGITLQHKRAMLGVVFSSAISGTFLG
                     LFAVKGFVIVGPGLASMSMFIDPNNGNNLIFASIGFVIAILGSFIITLIIWKEDTNTV
                     ESSIGDVVEEELEEEKEVNILVTPVEGKVIDLSKVNDELFASKTLGDGVAIIPTNGNL
                     YAPCDSEVVMLFETKHAIGLRTKNGAEILIHIGINTVSMNGDGFKTFVKTGDNVKEGD
                     LLIQFDLDKISHANLDSTVMIVNNNGADYAYKVLNQSYGNVKKGSILFDVKGGI"
     gene            complement(21409..22272)
                     /locus_tag="PC466_001553"
     CDS             complement(21409..22272)
                     /locus_tag="PC466_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HDF2768941.1"
                     /translation="MILSYFALLIRVVLLAFERVVVRLLGDEEGDIYKNIASSFLFFF
                     IGGVCLLPFSIMDRVSDWSFLIPCYISSLVYSIGSVAYVTSLATGEVSLVTPINSLNS
                     LFLLLLSVIFLGEGLSLAKVAGIIIMIGGVFILKKVSSFLKNVSVIFNNLPCRLMFLY
                     IFLQSVGRVLDKAFFVQVSPILYSTILYFFVGLNLFIFLAFKKKQKIICEIFSNKKGL
                     SILSGAINGYSYLALLIALNNLELSIAEPFSQVSMIITLILAHFIFKENIKEKIPGSI
                     LILIGGWLLLL"
     gene            complement(22327..23259)
                     /locus_tag="PC466_001554"
     CDS             complement(22327..23259)
                     /locus_tag="PC466_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacyl-tRNA deacylase"
                     /protein_id="HDF2768942.1"
                     /translation="MNNKKAVFFFCSDLKKDPVASNVIKCCEEIMDLNQTDIVIDDNF
                     VLEFKDKNNNLFHFVKTKDVISHNYKYYLPILNRHFRDYDFAGVVNWHEGENAPEHIL
                     TAHTIGDVPTGEFGNSNPRYFKNLINAIEDIKNENLLDEFTTLTEATHWSGTTYGEES
                     KLITEYSVPMLDIEIGSSSDSFNNSIAIQVLAKSLIRVFDCDEPLKTLLCVGGVHFEK
                     SFSDIIKNKEYNISIGHVLPNQWIVSGMYDDESGFEKLEKCINSIEGGIDCIVFHDKL
                     KGTYKEQCRKLGEKLNVPVFKHKILKNPKDLPIW"
     gene            complement(23345..23896)
                     /locus_tag="PC466_001555"
     CDS             complement(23345..23896)
                     /locus_tag="PC466_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2768943.1"
                     /translation="MQSLNEIIAENLKKIRKEKHLSLDKIAQLSGVSKSMLSQIEKCE
                     VNPTISTLKKITNGLKISFTSLMERQESDIELIQKSDIDHFIEDNGKYISYPIFPFDS
                     KRRFEIFMIEIEEGGNLDSNAELPGTQEFITVFSGEVTIKINGEDYIVSSGNSIRFKA
                     DVSHIYRNSGKGIAKMSMVVYYI"
     gene            complement(24125..24616)
                     /locus_tag="PC466_001556"
     CDS             complement(24125..24616)
                     /locus_tag="PC466_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768944.1"
                     /translation="MIDLKIENRKGKIHVKSSEIKDILELRPDFEYVQDISNTINQEN
                     ILVFDCQLTGNSFDMDDLDIEEILEELGEEIDESYFSVLFEDVRAYLKDATDEIEADL
                     QDNYLFDNLRCYFDIYNINQEFTDFKFVFLVSFKDIKISSLANLAKIVSKRQLIGASK
                     FYS"
     gene            complement(24644..25204)
                     /locus_tag="PC466_001557"
     CDS             complement(24644..25204)
                     /locus_tag="PC466_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HDF2768945.1"
                     /translation="MNKLNICIDIDGTITSPYHFLPYLNDIFNKNITEAECITHNWEE
                     LYGSGIRDVYAEFNNKYIHSYDEAKIVEGATEVISTLSKGHNLSFVTARHECLTDVTK
                     NWLSRQGFSDIDVYLLGSDYKVEKARELSCDIFIEDNPLNSVQLADDGVKVILLDTNY
                     NKDVKHQNIVRVSNWIDIEKIIKQGI"
     gene            complement(25356..26513)
                     /locus_tag="PC466_001558"
     CDS             complement(25356..26513)
                     /locus_tag="PC466_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HDF2768946.1"
                     /translation="MNKQSIGKLNMFFMGITQRNLDNRHFFIELEVIFKSGRKEFKGI
                     AIEEDNKYKFNFKGKSDLYTFNELLKNISKEAENYDGLVFKYVERGTIVVIEGDNKKV
                     NVKYLDNKEEVPKIDEFTASQIKNRDYYVKVGQANALLKEIGVLTKDGKIKNDKIRKY
                     NQIDHFVELIDSILKEIKDKDCITILDCACGKSYLSFVLNFYIKEVLKKNCYFIGIDY
                     SDVVIEASKNMAKNLGYKNMSFIKEDLTNYTPNRDVDLVISLHACDTATDMAIGLGIR
                     AKSEAIVVVPCCHKELLGQYRYEAMEPILKHGVFKARFADLITDGLRTLLLEGNGYDT
                     SVVEYISPLDTPKNLMIRAIKTKTNNDKALKEYKELKSQFGVEPTLEKLIY"
     gene            complement(26550..27491)
                     /locus_tag="PC466_001559"
     CDS             complement(26550..27491)
                     /locus_tag="PC466_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768947.1"
                     /translation="MRWILVFIFLYLIPLVVIFRNYKNFKRSCIYSSIYVVLATTIMI
                     SNIYMSGLNKIKESMYYHNYISDETYDEKYVSNFKEKESTDLKQDNKKNEEISNNKNL
                     NNKQDRNIQNKESNEEGSNDIKEKNNSDSNVSVNNKSEKQEDNTKENNKYTSKEKNSE
                     DIKKIDMESIGIFKKEIYNIERAALVPMRECIPYTKDIAKNITKLSSIKKDVTNARNK
                     CKEVVKEYENMQIPELSKEKYTETLSNARDDVKKAYELREKSMESALKLINTKSPKYI
                     GKITEYLDLSDKQIESFKNRLNDLKEEINNSETNNIN"
     gene            complement(27578..28270)
                     /locus_tag="PC466_001560"
     CDS             complement(27578..28270)
                     /locus_tag="PC466_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HDF2768948.1"
                     /translation="MSLYAIGDLHFSTSVNKPMNIFGSNWDGHEKKIIDNWKEVVKEE
                     DMVLVLGDTSWGINLSEAKKDLDIISKLPGQKILIKGNHDYWWTTVTSLNKLYEDMRF
                     IQTNFYEYKDYAICGGRGWICPNDVKFDETDEKVYKREEHRLRLSLESARKSGHSKII
                     VITHYPPTNDKLEESLFTKLFEEYNVEKVIYGHLHGKESFKMGLKGIRNGVEYTLASC
                     DYTEFNLIKVHD"
     gene            complement(28380..29192)
                     /locus_tag="PC466_001561"
     CDS             complement(28380..29192)
                     /locus_tag="PC466_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HDF2768949.1"
                     /translation="MEYEKWNEILAPYEHAVEELKIKFKNIRKEYLAKGEYSPIEFVT
                     GRTKKISSIISKLKRINAKDIETEIDDIAGIRIMCQFVEDIYAIVDLIKVRNDMTIIG
                     EKDYITNYKDSGYRSYHVIIKYPINSIAGSKEIICEIQIRTLAMNFWATIEHSLKYKY
                     DHYIPETLAERLRRASDAAFLLDQEMSEIREDIMKAQAMYQMKSIAIRDTLNRIQELY
                     DLGDTHKAMQYQRKLDRTETDKNITEILELKQEIDILLEQYKDTKVDDKVVQ"
     gene            complement(29243..30154)
                     /locus_tag="PC466_001562"
     CDS             complement(29243..30154)
                     /locus_tag="PC466_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF2768950.1"
                     /translation="MNLTKVKGNTFFIKGGTNTGIYVFEDNTALMIDPGLCGSRPRRV
                     NKVLDENNIQVRYIINTHGHDDHYGACNQFKEYYKDVCIMSSEYDKLYIENPELFSKY
                     IVGGKSNVFMDNILKNKMLDDIKIDKSIEVGKIELNNEMFDIIEFQGHTPGSIAVLTK
                     DNVIFVGDLLIGDEILSKYDFLFLYDIQEQINSLEKLKNIDFEYLVLGHGKQVISKED
                     SYKLIEKHLNALKKYLYQIRELLVEPKSLEILLKNIINNNNLSNNYKEYHFFKSSLVS
                     VISYLVDLEEIGYILENGELLYYTKTK"
     gene            complement(30213..30944)
                     /locus_tag="PC466_001563"
     CDS             complement(30213..30944)
                     /locus_tag="PC466_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkgJ family cysteine cluster protein"
                     /protein_id="HDF2768951.1"
                     /translation="MTSIKNKDILNCIDYSIKNKLFDKLNDVYKSLPVGNCSGCGNCC
                     MESVGINLIEFLNIFCYLEDRVDLKKSCISKILDYYFEEYTRKNPCPFKDTNNRCLIY
                     EVRPLNCRMFGHWKKEDYNKNLDNVIEKNNNYRELMKKQYGFEINDEVVNYRIDYCDR
                     FIPNKDYLSKSKRLSFFDELMILDSNIYSSGNIDIDFRDRGIVEYFIESLLYRNLAYN
                     VKIRISKEYKIRKRTIDRIKRIVLV"
     gene            31033..31284
                     /locus_tag="PC466_001564"
     CDS             31033..31284
                     /locus_tag="PC466_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768952.1"
                     /translation="MNRYTKIINMMGSYYTKDFEKEKKNVIKVREVKEDTVRKFFLQG
                     DCEVLVVFEDTGKEILIDDFSPEEDIKKYLGTKFINKKR"
     gene            31517..31936
                     /locus_tag="PC466_001565"
     CDS             31517..31936
                     /locus_tag="PC466_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768953.1"
                     /translation="MQIYFRVKAVGKRKPMLELTPFDVSDNINCLKEAISEIVSKNVL
                     EYNEKIPEKSIINFLTNEEIESQADIGKVGFGSIYNENKQSVEKAIEVALQAFEDGIY
                     KVLINEDVIEKLDSPINLKSGDIFTFIRLTLLAGRMF"
     gene            31961..37018
                     /locus_tag="PC466_001566"
     CDS             31961..37018
                     /locus_tag="PC466_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4132 domain-containing protein"
                     /protein_id="HDF2768954.1"
                     /translation="MLERTRVEKNPKIIENFKNNFTKSSSKQYYDLAKSLWDCIENSS
                     YYYREPEDKFLNMIKKYYNCHYYEIKNMDELLSGPLKNALELIFTSEQVEELCQLIKR
                     KMDYTYSGGYYRKGYRSNKLVDYFRGIIRFISNYVDLIYYDFSVIDYLTLPNKVLYYD
                     SIMSDKIALEIDKGNQKVTSALEEVIFGENQTALLTRQMIIGIMKSHSDKCYEMLSKL
                     LLAAKQQEGLRQQIVESLDEGTISASIYMLKTILDNNLERFSSVIRALDTWTGLGFSD
                     QKPGIIRKCLELSYKSLTDEKFRIESINSNDNLEIYFALWATATYNIYDSYSLIENLL
                     SCQEKYKKLVALYFLSHTESTYFKHSIASKNIKGDDLEILAWVITNFYVEGSVGYYYS
                     WQNRETNFDLSNTPIDKDFDARKEQFESLKHTLEILNSKTKSFSGSVFPWTWIEISSH
                     EILKCMMTLTAYDMNAQFIDVLMENCHLMSSDLRASLIVNFVNEPKTDRQREFLLECL
                     SDKSVSNRETVLSLLRKLELTDVELDKITNLLSLKTSSIRQTVIKILLEQDDSNLENI
                     ASSLIKSSNSQKCLGGLEIVNLLKDNSDRQELYNKLILLIEDIDKSKKNTSQVQILID
                     NLLGKAKNDYCKENGFGIYNPENKVQIPEQFDFKDDSNSSSKLNKIISNISLSTSEDS
                     VSVATKKEAKKILDTDINKIIKVYEKFDELITENADYEYEVERWSGNVDKVLLGYSTY
                     NLTPIKYKVSNDTLDNYPLAELWRETSKKLDLDYKLILDILFYSISTCGYNETEKSWF
                     SSIYSNVLDSKKQNKIYTKLEKFKFNGLTRKLLRVLLNEFDHKEIFNYCLEIYYKLRN
                     LLTIEQCKKQRVEFTKNYYRQNEYCPALNAPILNYWLDKAHSFIYDDISFTKFFYTTF
                     SNYQLLEYKFPFYTSINVFARAHELGLMTEEQVNREMISGYNASNIIRTLTNPRWAGD
                     TLEKYPWLKDNLKTVTNRIIEIESRRGDMPTEVSHLANNIQYFEGIDYFVNILVALGK
                     ETFQRGYSYGSNYSKKDVLSSLLKNCYPTKEDDSKKLKSLLKNTDITELRLIESAMYA
                     PQWVNIIEKYLNWKGLKSTIWYFHAHINEGFSAQKESEVALFSPISPRSFIDGAFDVD
                     WFLDSYKTIGEERFNILYKSAKYITSGGNSHRRAQLYADATLGKLDKDMLMKEIETNR
                     NQDKLRSFSLLPMKKGDLKEATFRYEFIQKFAKESKQFGAQRRESESKACTIALENLA
                     RSAGFGDVNRMMWALETEKLNEVAHLFKPKDIDGTSIWIDVDESGKASTKVQKGNKSL
                     KSIPKAIAKHPYVLELKSVQKDLKSQYSRAKQSLEQAMKNEIVFTVKEIANIYKNPVI
                     CPLIKNLVWVCDDNIGYVYNDKSKFFICNIEGETYKLTAKNKLKLAHPVHLFESGKWS
                     EFQHDLFSKQLVQPFKQVFREYYRINSDEISEKTISRRYAGHQIQPKKTVALLRNQLW
                     TVDYEEGLQKVFYKENIVAKMFALADWFSPADIEPPTIETVEFFDRKTYKSLELASIP
                     PILFSEVMRDIDLVVSVAHAGGVDPETSHSTVEMRIAIAKELLLLLKINNINFEGSHV
                     LITGNLGEYSVHMGSGIVHKKGMGALNILPVHSQSRGKIFLPFADEDPKTAEIMSKIL
                     LLAEDNKIKDPSILSNL"
     gene            complement(37178..37915)
                     /locus_tag="PC466_001567"
     CDS             complement(37178..37915)
                     /locus_tag="PC466_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2768955.1"
                     /translation="MIKVLICDDDKIVRDDIANIVKESGYVDYVKKVKDGIEAIEFIK
                     SEKIDLLIIDIDMPYKNGIDSAKEILSIDKDIHIVFVTGFADYSLESFKVHPIDFIVK
                     PFKKEKILDSINIAIDHINSHKIAKNNFIEDTLFVYKIRKQIHMINFDDIVMFEKNSR
                     AINLYTRDEDTIKFYENFDDLKKRLPPNFFMTHRQYIVNLRLIHKVIPINKSSLEIKF
                     INFQESATLNKSLEKDFLYRFYRVKRF"
     gene            complement(37934..38869)
                     /locus_tag="PC466_001568"
     CDS             complement(37934..38869)
                     /locus_tag="PC466_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HDF2768956.1"
                     /translation="MENNFIFPIVILTLFIFSNLIMNKYRFYKELDILKRGILTFFVS
                     CFVWILFMEGIEYIQLSLGYNFLLEGVLNIILFLILIILSFYIGFKFIRLLDNNNKQE
                     YKLQKLDSKINHKDNIIVKLRSQKHDYLKHLQVVYSLLNTGLAEDAKEYITNISNSFK
                     SKNSRYGKVSYLDAIASLKYEECLEKNISFDVYIQDFMDNLEIEPNDMSSVLLNIIDN
                     AIESLSAIQKEKKYIRLHAYEDEFQYIIAIKNNGPKIHNVESIFLDGFSTKEGQDRGF
                     GLYLVKNILDKYDYSILVNSDDFLTEFVILIPKYY"
     gene            39077..41662
                     /locus_tag="PC466_001569"
     CDS             39077..41662
                     /locus_tag="PC466_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HDF2768957.1"
                     /translation="MKDNLKIALRYIISYKARSLAIALSIILATSLIVGIGTLSRSAQ
                     QAEVDKLKRETGSDHVYFKDINKNQLEYIKSRKDIKNLGITSHYGYTDPNERLAINLE
                     YANKNYLTNQSKLIKGHLPKASNEVVVEKWILNSLGLKPEINQNITFKLYQKEKPETF
                     KVVGILEDRPIEKNKGTCEIFLNLNESKLDKFSYAYIEFNNGIDINTSIDNIVKNTML
                     DENSVGKNKMLIESTRENGTLDNSSKYTAITMSLFSGIVIYSIYVISIYQRIQEYGIL
                     RAIGSTNFKIFKFMFYELFILALIAIPIGICTGIGGAQIFNRTAGNIQFEGNVTVTPF
                     VIPDKIILLSIGSIILTILIISFFTYLKIRRISPIDSIRKTFGTDKNINKVNSLISKL
                     TLNISVTKSISAKNIFRNKKGFIIIILSMSLGGIMIIKENYKYSFSDIQNKNGQEETY
                     MNADFILTNFFLKLNQSNKADSFKDIKGLNDNQIDKIKNINGIDKVKTASILDTRIEV
                     DKLNGLDYYNIINSTPYYKDFPLFIKNKNTGKYTMKQKLRGYNDEMINSLEKYLVSGS
                     INLERMKKENLAILYVPQVSKTNKYKLSYTPGTETPAVDIKVGDTIKVKYPKGEIDQD
                     LYIKLKDNYEYLEYEFKVGAIVSYPFADNYLYSGDQGIDVITSNDYLKKLTGVDKYNV
                     VYVDINKNANVKKINTLLGEIGSESPGTTTANMLMEKENFDKMTARALTYAYGIVAVM
                     FIISVFNIINNISYNLTSRTSEFGMLRAIGISERGFKNMILYEGILYGILSSVITIVV
                     GLIIQFRMYYTYNFVSYGLGFSIDYKIYILVVLANIIVGILATYIPLRKINKISIVEA
                     INITE"
     gene            41674..42345
                     /locus_tag="PC466_001570"
     CDS             41674..42345
                     /locus_tag="PC466_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2768958.1"
                     /translation="MPILEILNLGKIYGKKETAVHALKDANLKINKGEFVAIIGPSGS
                     GKSTFLHLVGGLERPSSGTIKVDGKDICCLSDKKLAKYRRQKVGFVFQQYNLIPVLNV
                     KENIELPLKLDNKKVDEEYIEDIINLLGLSERKNHLPNQLSGGQQQRVAIARALSAKP
                     SIILADEPTGNLDSKTTEEVMDLLKSSIKKYNQTLIIITHNENIARKADRIISIIDGE
                     LKLTL"
     gene            42372..42713
                     /locus_tag="PC466_001571"
     CDS             42372..42713
                     /locus_tag="PC466_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768959.1"
                     /translation="MLLILDNLNLNLDFDYRIIREENDDVDIFIDINYRSLDIDTDGS
                     NLFNSRIQFPFVRALILRINKNNQCMTIHLLRDIDLFSAFANFEVDYTDSIINIKNQN
                     EKVILNKSIKK"
     gene            complement(43073..45715)
                     /gene="adhE"
                     /locus_tag="PC466_001572"
                     /gene_synonym="adhC"
     CDS             complement(43073..45715)
                     /gene="adhE"
                     /locus_tag="PC466_001572"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HDF2768960.1"
                     /translation="MEKKEKVVEKSNVEVCSPEIVNSVETLRMRLEEIRLAQKEFATF
                     TQEQVDKIFLAASTAANQQRIPLAKMAVEETGMGIVEDKVIKNHFASEYIYNAYKDTK
                     TCGVIEKDEAFGFTRIAEPVGVLSAVIPTTNPTSTAIFKSLIALKTRNGIIFSPHPRA
                     KNCTIEAARVVHDAAVKAGAPKGLIGWVDVPSIELTNVVMAEADLILATGGPGMVKSA
                     YSSGKPAVGVGPGNVPAIIDESADIKMAVSSILVSKSFDNGMICASEQAVIVPEKIYE
                     EVKKEFKYRGAHFLNKEETEKVGKVVIIDGSLNARIVGQPAHVIAKMADVEVPKTARI
                     IIGEVESVELNEPFAHEKLSPVLAMYKSKSFEDAVAKAEKLVADGGYGHTSSLYADSI
                     NHPDRVEKFVNAMKTCRVLVNTPSSQGGIGDLYNFKLAPSLTLGCGSWGGNSVSENVG
                     VKHLLNIKTVAERRENMLWFRAPEKVYFKKGCLGVAAREFKDVMDKKKAFIVTDSFLY
                     NNGYTKKLTDLLDEMGIKHTTFFDVAPDPTLACAREGAKAMADFQPDLIIAVGGGSAM
                     DAGKIMWVMYEHPEVDFQDLAMRFMDIRKRVYVFPKMGEKAYFAAIPTSAGTGSEVTP
                     FAVITDQDSGVKYPLADYELMPNMAIIDADMMMEMPPRLTAASGVDALTHALEAYVSM
                     LRTEPADGLALQAGKIIFEYLPRAYKNGKNDKEAREKMAMASTMAGMSFANAFLGICH
                     SLAHKLGAFHHVQHGVANALLINEVIKFNCAEAPNKMGAFSQYRYPDCIQRYAEFASF
                     AGIKGNTDQEKVDNLIKAIDELKARVGLPKTIKEAGVEESKFLETLDVMVEQAFDDQC
                     TGANPRYPLMSELKEIYLKVYYGK"
BASE COUNT        15423 a         7655 c         5621 g        17280 t
ORIGIN      
        1 gtttccctat atgctgacta ttttagctac taactcatga ctaaagtcac gagtgtacgt
       61 agctattttt taatcaaata tatatattct ctatatataa cttcttctcc attaaataat
      121 atctcatcat tttcagtgtc tacttgagtt cctggatttg aaacttcact tccatttact
      181 actacagacc cttgtttaca atacttcttt atttcacttc tacttccata acctaaattt
      241 gaaagaattt tatctatacg ttgcttttta gccattaaaa atgctctcca ttctcataat
      301 atttttcttt ttcaaatact gtaaatgcta aatccatact ttctacatct aaattatttc
      361 ttatactatc agttattatt cttgctacta tatcttgtac ttcttgtcct ctatcaaacc
      421 aagctacttc aacaaaagga tatacatctg ctattttacc atctcttatt gcaactgact
      481 ttatacattc tatttcaaag tagtctcttg gacattttac agcttcaact aaatcattta
      541 tcattttttt acttatttta catatatcat tttcattaat tcctcttatt tttatctgtg
      601 gcatagttta tctcctttat tttaaatttt tagtgaatta tcatccactt aattcccttc
      661 gataacgttt gaagtggtaa cttcttggtc aagacaacta ttgttatcag tatctccaaa
      721 ctaataaggt agttcctacc cttatagtta gcattatata gctaattttc ctaaattatt
      781 tatattcttt attattttat ttaatcctat tgtcttctat ttaacattat acttgtaatt
      841 tatagttatt acaatttact atatactttt tttgatttaa cgttataata taagtgatgg
      901 gtaaatttta aaagttaata ggaggagttt aaaatggcat taattactac aaaagaaatg
      961 tttaaaaaag cttacgaagg tggatttgct ataggtgcat ttaacataag tgacttagaa
     1021 caattacaag gtgttttaaa agctgctaaa gctaaaaatt cttatgttat gatacaagct
     1081 tctatgtcag ctgttaaata tgctggacct catacattag ttgaaatggt taaggctgct
     1141 tctgatgaaa taggtgtaga tgtagctctt cacttagacc atggtccaaa tatggatgct
     1201 attaaaactt gtattgatgc tggtttctct tcagttatga tagatggttc tcattttgac
     1261 tttgaagaaa atgttagaat aactaaagaa gctgttgaat atgcacactc taaaggtgtt
     1321 gttgttgaag cagaacttgg tgttctagct ggaacagaag atgatgttac ttctgatgtt
     1381 cacaagtata ctcaaccagc tgaggcagtt gagttcgttg aaagaacagg tgttgattca
     1441 ttagcaatag ctattggaac ttctcatggt gctttcaaat tcaaaggaga agctaaatta
     1501 agatttgata tactagaaga aatccaaagc aaattaccag gtttcccaat agttcttcat
     1561 ggtgcatctg ctgttgacca aaacgctgtt gctacatgta atgaatttgg tggaaatata
     1621 gctggtgcta aaggtgtacc tgtagatatg ttaagaaaag catcttctat ggctgtttgt
     1681 aaaataaaca tggatactga cttaagacta gctatgactg ctgctatcag aaaattctta
     1741 gctgaaaatc caaaagaatt tgacccaaga aaatacattg gtgctggtag agatgctata
     1801 caagctgtag ttgaaagcaa gatagatgat gttttaggtt ctgctaactc tataaactaa
     1861 tataactttt aaatatttat aaaagaaaag agatgactta aagtaattaa atttattttt
     1921 aagccatctc ttttaagttg tatcaattat gtatcttata atattttaat tatattgtct
     1981 ttttaaactg acagctaaac gtgaatatgt ccactcttta tctttctatg gatggtagaa
     2041 ggatatatac ctataacttc agcagccttt gttattgaac catacttatt tatagcctta
     2101 cttatcatta tttggtccac tattttatat gcatcattaa gattcataat tccatttacc
     2161 actattggtg ataaatcatc tgtttcatta tcaatcatat ctaaatttat cagcatgtta
     2221 aattcatctt ctccaattac atttttagct gataatacta caaatctttc aatgatgttt
     2281 tttaattctc ttatgtttcc tggccaagaa tattcttcta ataactcaat aactttaggt
     2341 gaaacttcta cttctctatt gtacttttca ttgtaaagtt ttaagaaata atttactaat
     2401 ggtactatat cctcttttct ttctctaaga ggaggtattt ttactggaat aacacttaat
     2461 ctatagtaca aatcttgtct aaatttaagg ttatttctaa ggtcttcatg agaaatatta
     2521 gtagcactta tatatctaac atctattttt ataggcttac taccacctat tctagtaata
     2581 gtattttctt gtataaccct aagtaatttt ttttgcatct gcattggtaa ctcacctatc
     2641 tcatccaaga aaatagttcc accattcgcc tcttcaaaaa gtcccttttt accttttttc
     2701 ttagctccag taaaagaacc ttcttcatat ccaaaaaact ctgactctaa taattcattt
     2761 ggtatagctc cacagtttat agctataaaa ggtttgtctc tccttgaact atacttatat
     2821 attgttcttg ctattatttc ttttcctaca cctgattctc catttataaa tatagaagaa
     2881 tctgaggctg cagctctctt aacaactttt tttatattgt ccataatctt actttgactt
     2941 atatactctg tgtcttctga tatatcacta tattttatct gagattcaag cttaataacc
     3001 cttgaaatat ctctccctgt tagtactcct cctgtaagct ttcccttaga atcccatctt
     3061 ggaactgccg tatatgcaat aagcttccca tctgggtaaa cgatatttct ataaatcttt
     3121 ttcttcactt taagcatgtt taatattatt ggttcttcaa ctaatccttg tctcacaagg
     3181 tctgttatat ttctaccaag tacctcagtt cttttaaaag gtaatatctc atcactgaca
     3241 gtgttcatct tttcaattac cccatctttg ttaaacacaa caacaacttc atctatatgc
     3301 tctattatat cttcaattac tttatcagat attagagact tctcaaataa ataaactata
     3361 ttattttcat tattattatc tttcatattg tatatatgtg cagtcatcct taactctctg
     3421 aaagctattt tctttttact atctgtcagt atttctgttt tgtcaaaatt tgaatctaat
     3481 tcatttatat ttctaggctt ttttatatct agaaaactaa aaatactatc tattagatga
     3541 ttacagtata ttatttcgcc tgattcttta cataaaatgg ctggattttc tacatgttct
     3601 ataagcccta ttaaattatt atccattaat attcgcacct ttcattaagt aatttattga
     3661 actacataca aaatttattg tttgcttaca ataaatacca tcagcacata taatcaactc
     3721 cttataatat tcgtcttttc aagtagttta tttcattaaa acgtaactaa gatataattt
     3781 taatgattat agtttgttaa aaatttcatt ttgcttttaa ttgtatttta tcacatattt
     3841 agtaattatt tgtctattta atacaattta attaaattta agatttattt aaaaaaacaa
     3901 agataatcct tacagaatat aactcacaat ttgtaagcaa tatacatata aggattatcc
     3961 agattatctt gtattataaa attttattca aacagacttt ttaataactg acaaatacac
     4021 actagcaata acttatcaaa gggttaataa ttatgttact aactaataag acttattcaa
     4081 tcagtaatat ttatatagtt tgtatctatt aagcttttat agcttctaat aaatcatcaa
     4141 cgctatctaa tttttctata agcattggaa ctatttcatg taagtctcca actactccat
     4201 agtcagcgat ttctaaaatt ggagctgctg ggtttttgtt tatagcaatt atgaaatctg
     4261 atgattgcat acctgctaaa tgttgtattg ctcctgatat accacaagct atatataggt
     4321 ttggtttaac agtagttcct gtttgaccta cttggtgaga atggtctatc catccagcat
     4381 caacagccgc acgagaagaa ccaactactc cacctaattt gtcagctaat ttcttaagca
     4441 tttcaaatcc ttctggtcca cctaatccta aaccacctga tactataaca tttgcatctg
     4501 taagagatac taaatctttc ttagttttaa ctgtttctaa aacagtagtt cttatatcat
     4561 cttgagttat tttgtagtct aatgctataa cttcaccagt tcttgtttcg tctttttcag
     4621 ctttatccat aacaccaggt ctaactgtag acatttgagg tctatggttt ggacaaatga
     4681 ttgtagccat tatgtttcca ccaaatgctg gacgagtttg ttttattttc ttatcttctg
     4741 ggtctatttc taacttagta cagtcagctg ttaatccagt tccaactctt gaagctattc
     4801 taggtgctaa gtctctacct atatgagttg ctccgaaaag cattatttct ggttttattt
     4861 catctattgc atcttttatt acttttgtat atgcatcagt tgtatatttt tctaaaagag
     4921 catcatctgc aacataaact ttgtcagctc caaaagtgat taattcttta gctaatccat
     4981 caacatcttt tcctaataat attgcacaaa gttctgcatc tacttcttta gctaattttc
     5041 ttccttctcc taataattct ataactactg gagctatttt tccttctctt tgttctgcaa
     5101 atatccatac gtttttataa gaacttaaat cttttatatc attcatagtt tgtactcctc
     5161 caacttatat aatgtgcttt tgttttagac cgattattat tttactagct atttcatcag
     5221 ctttaccttc taagatttct ccttttcctc ttggttcagg agtaaatgat ctaaatactt
     5281 tagttggtga tgcttttaaa ccaacttctt ctttatttac atctaaatca tcaattgtcc
     5341 aaacttttac atcatgttta tatgctttta ctattttatc aacagacatg tatctaggtg
     5401 tatttaactc ttttactgct gttaaaagta caggtgtact tacttttatt aattcgtatc
     5461 catcttctaa ttgtctttga actattatat cttttccttc tattttgaaa tcttgtacat
     5521 atgtaacttg aggaatgtct aatttctctg caatttgtgg tccaacttgt gcagtatctc
     5581 catctattgc ttgtcttcct gcaaatatta tgtcatagtc acctacttta gatattcccg
     5641 ctgcaatagt atttgatgta gcccaagtat cagctcctcc aaatgctcta tcacttaata
     5701 atattgcatc atcagcaccc atagctaaac actctcttag cataaagtct gcttgaggag
     5761 gtcccattgt tataactgtt atagttacat catcatgctc atctttaatt tttaaagctt
     5821 cctctaatgc atttgcatca tctgggttta atatacttgg aactccatct cttataagag
     5881 tacctgtttc tttatttatt cttacttcgt tagtatctgg aacttgtttt acgcaaacta
     5941 atattttcaa agtctatacc tccaatttca ttagattatt tattatttta atacgtttga
     6001 tgaaattacc attttttgaa cttctgatgt tccttcgtat attgatacga ttctagcatc
     6061 tctgtacatt ctttcgattt cataatcttt tataaatcca tatccaccgt gaagttgtaa
     6121 tgctttataa gcaacttcat ttgcaatttc tgatgcatag tatttagcca tagcagattc
     6181 ttgagcaact ctcattcctg catctctctt ttgtgctgca tcataaacta atcctctagc
     6241 tgcacaaact tttgtttcca tgtcagctat agtaaattga gtattttgga atttagctat
     6301 aggcttacca aattgaactc tttgttttgt atatttaaca gcttcatcta aagcaccttg
     6361 agctattcct agagctaagg cagcaacacc tattctacca acttctagag tacccattgc
     6421 tatcttaaat ccttgacctt cttttccaag taagttttct tttggaactt taacgttttc
     6481 aaatattaag tcagaagttt cagttcctct tatacccatc ttatcttcat gagctcctgt
     6541 tgagaaacca tcccatttac tttctactat aaacgctgat gttcctctaa gtcctttact
     6601 tctatctgta actgctatta ctatagctac atcacagaat ggtccattag ttatgaaagt
     6661 ttttctacca tttaatatat agtggtctcc aactaattct gctgttgttt gttgtccacc
     6721 tgcatcagaa ccagctcctg gctcagttaa cccaaatgct cctattaatt cacctgttgc
     6781 tatacctttt aagtattttt gtttttgctc ttcagtacca ttgtaaagta ttggtaatga
     6841 agcaagagaa gaaccagctg taacaaaagt agctgttgaa gcacatcttc tagctatttc
     6901 ttccattact atagcgtaag aaacatatcc tgctccccca ccaccatatt cttctgggat
     6961 attactgctt ataaattttg catcagctaa ttttttgatt aattccttag gcattacacc
     7021 tgttttatcc atttctgctg gtaaagtatc taattcttta ctaacaaaat ctcttactgc
     7081 ttttcttaaa agttcttgtt ctttgttata taacatagct tcctccaatt ttcatatttt
     7141 atagtaaatt tattttaatg aacttacgct aaactcatca tctcagcaaa agtttgaata
     7201 cgagttctgg cttgttcatt attctgagtt tgttggtcga tttcaacata taaagtaggt
     7261 attccactat cttctatatc ttttctaact aaaggataat cgtattcttc tgggtcacag
     7321 aatttcatca tacagaagat aacaccatct atatctttct ttttaacttc atctactata
     7381 agtgacccac gttttttctt agggtcataa gctaatgaac atccttctat gtttgaccat
     7441 tgtcttgcta atctctctaa cgcatcatca cctgctggta catctgttct gaattgtctt
     7501 gtttcttgtg ctaagtcgtc agctacaact gatatattgt tgtcttctaa aatgtctaat
     7561 atatctttag aatcagctaa tatacctgtt aataaaactt tttttccaga acagacttct
     7621 tctggcatag catttaattt tgctattaaa tctttcacta gctcagtatg ttcttctttt
     7681 ctcataaaga acccactttt aattactaag cttcttattg atggttttat agtattagaa
     7741 tgtttataag ctacttcaac aaagtctctc atagtttttc tatgttcatt gtaaacttct
     7801 atactttcat gaatttttgc ttcttctatt tcatatccac aaatttcttc aagttctctt
     7861 tttacacctt tgtactcact gattaagtat tttacaccag cttcaagttt tctattttgt
     7921 gggtgtacta atgatatata ttttatatga ggtactgctg atttccagtt ttgtcctaaa
     7981 caaattagtg tatcacacat acctggtata ataactccag ataattcatc ataagcacct
     8041 tttaatccat attctaaaca tgattgcatt attgaacatg caaatgcagg gaaatattgt
     8101 ttagctaaat ctaattctgt ttgtcctccc catataccaa ctggaagcat tccagctgca
     8161 tgtataattt cttctgggca ataaactggg aaacaaccta tagctttttt accagtttca
     8221 tttttatatt tttttacagc cgcatttgga ttttcaacta cttctttcat tttagataaa
     8281 atagcttcca ttatatctca cctctattaa gtttttttct ttcttccatt acttcaacta
     8341 aaccttgaat tcttgtttca aattgagcat tagtgaaagc tctagggtct gcttggtcac
     8401 catcaaatcc agcatatggt aatccagttt cttcagctgc tcttctttgc atttcatatt
     8461 gtattaaact cataagttta cagcttctgt tcatatgata gaatgctcca tcacatttac
     8521 cctctactaa agaatcaact ctatattttg tcatacggtc taggtttaca ttgttaaaca
     8581 tagtactata tgctactgcc attccatcta aatcattaac ttcatattgt aatgcccaag
     8641 catgtgggta aacactacct gtcatgttaa ctccaaattt agctaatgtt ttcatcttgt
     8701 atcctatata tggccaacaa ggtatacctt ccatcattat tctgtatttt tcttcccctc
     8761 tgaaagaaga tttaccagtt ttcatgttgt cttctaattc ttctataagt aacttaaatg
     8821 cttctgtagt ttctttttta cctctagcac aaactattac agccatgtaa gtaaataagt
     8881 caaatccatt cattggagaa ggagaagaat ctgctggtaa actcatagaa tacttccata
     8941 gtcttccgtt ttcagctgat attttcatta cttcttcaaa cttcttaggg tcaaatttct
     9001 ttcctgatat aatttctagt tgttttatag cttcttcaaa ttgagcttta atataatcta
     9061 ttcttgattg agtaacttcg tcttcattat tgaaagttgt atcaatcatt attaaaggta
     9121 tatctaattc tcttgaaata ttttcatacc attttataac ttgattacat atattgttac
     9181 agcaaagtag gaaatctgga gctggcatat ccaaagcttc acatccacca ttttctaaaa
     9241 gaccaaaatt tgttcttgca tatgcacata ggtcaataga atatccttta gattcagcta
     9301 tttcacataa ttctaaagaa ccttttttag ctgctactcc agctgcttgg ttttctggat
     9361 ataatacgtt taagtcaaat acttctgcta actcttgagg aaatactgat gttgaccaac
     9421 ctacaggtct tccttcttct ttagctttaa atgcatttgc atattgttca gctaataaat
     9481 cattaattac tactctagct tctttttttt cagacatttt catccctctt tttatatatt
     9541 tttcacttct ttttgtgatt cttttgcttc atcaaaagca tataacgctg ctcctaaagc
     9601 accagttaat tgaggtatat caggtacaat aatttctgtg ttgatttctc ttgccatagc
     9661 tcttacaata ccactatttc tagcaactcc accaaccata actacatttc tttgtactcc
     9721 tattcttttt actaggctag aaactctctt tgctactgaa gtatgaatac ctgccactat
     9781 atcttcaatt tttgcatttt cagataaatg tgatataacc tcagactctg caaatactgt
     9841 acatgtactg cttattgata cttcattttg agaattcata gatatacttc cgagttcaga
     9901 tacatcaacc tctattattt ttgccattac atctaaaaat cttcctgtac ctgcagcaca
     9961 tttgtcattc ataagaaagt ttaatagtct tccattatta tctaatttta atacctttgc
    10021 atcttgacca cctatgtcaa taatggttct tgtctctgga attatgaaat ttacccctct
    10081 agcatgacag cttaattcac ttatttgctt atcagcatct gaatagttca ttcttccata
    10141 tcctgtaact acaacttttt taatatcttc tcttgcaaga cctgtcttgc catataattt
    10201 ttctaaaact cttgatggtc cagtagtccc agtaccagag gatattgttt cagaagctac
    10261 aatatcttcc ccattcttta agattactcc ctttgatgca gttgaaccta tatctaatcc
    10321 cattgtgtac atctttagca ttctcctttt aaaaaatcta gaattactaa ttaatatctt
    10381 acaactttac tatctttaaa gttatttatt ttctcttcat cgtagcctaa agattttaat
    10441 acttctacag tatgttgacc tacttttggt gctggtgtat attctttaat tccttcattt
    10501 ctaaacataa ctggagtatt aactaagaca cctgtatttc cgctatcgta tgttttctta
    10561 aataagaagt catttgccca agcttgttcg tcatctaata aatcttcaca gctttgaatt
    10621 ttttcaaatg gtaagtctgc ttcttctaat aaagctgacc actcgtctaa tgttttttct
    10681 aacatagctt ctccaactat cttaactaaa tcttcaacat gattaaccat tgaatctatg
    10741 ttattatatc tatcatcttc taatatatat tctctattta taaccttaca gaatttgcct
    10801 aaccacttgt tgtattgtat taaagctaat tgaatccatc ttccatcttt acatttatat
    10861 gtagtcatta atgggctgtt tggattttct cttgataaag gcatttcatt tccgtattgt
    10921 gctgttgtta tcattgttcc cattccatat atagctgtat ggaaaagact tactgttact
    10981 ctctcacctt taccagtttg agctttttta tgtaatgctg ctaaacttcc tgctgctagt
    11041 gctagacctg catagtggtc accaaatcct gctgctgtat ttgctggaga tgttcctttt
    11101 tccataacag attggctaac tcctcctctt gcgaagtatg cagtatagtc aaatcctggt
    11161 ttatctttta aaggtccttt ttcaccatat cctaatattt gagagaatat taatcctgga
    11221 tacttatctt ttatttggtc ataagctata cccatttttt ctaatgcttg aactctaaca
    11281 ttagttacaa atatgtctgc ttctgataat aatttatgta atatttctac tccttctttt
    11341 gattttacat taatacttac acccttttta tttccatttt ctaattcaaa catagggttt
    11401 tcatcatctg atgctggaga tttaaatgtt ccacccataa ctcttattcc atcaccttct
    11461 ataggttcaa tcttaataac ctctgcaccc cagtcaccta acatttttgc acaacatggt
    11521 gctgcgatga aacttgaaag ttctactact ttaactcctt ctaaaagcat aacgttttcc
    11581 tccttaatag tatcaattat aaaatttcga ttaaatcact cataaaatac ttttttctga
    11641 tattaactgt ctgatgtcaa agttcctaat cttatctaaa ataacttaaa aattattaaa
    11701 attatttttt attgttttat tgtcttacac ctatattgtt aagcatttat cgtgccaact
    11761 ttatatttaa tcaaaatatc gcttgatttg aatgtttttt aacaatatgc aattgaataa
    11821 tctttttcat atcgtggcat cttgccacta tccattgcat tttgctattc tttctatgct
    11881 tataaaagtt ttttttatat atttttttat gaaaaagctt gacatttcaa aaaaagtttt
    11941 cattgctaaa ctcaaaaaca catgttatca ttgtaattaa tcagcaagtt agttaactaa
    12001 tttcaaactt agataatttt ttaataatat ttaatctaaa aaataacaat ttctttgata
    12061 aattttagag taattattac attaaataaa aaattactaa atatcaaaat aacacaggga
    12121 aaacaatttc aaaactaaat ttttaacctt aaaaattttg tataaaaaat ataaccttat
    12181 atgctacata ttatttctaa atgaaaaatt accataataa tttaataatt acaggagggt
    12241 attgatatga aaatactagt atttggagca cgcgattatg aagaaccagt aataaaaaaa
    12301 tggtctgaag aacataagga tgttcaagtg gatatttatc ctgaaaacat gactgaagaa
    12361 aatgtagtta aagctaaagg gtatgatggt atatctatac aacaaactaa ctatatagat
    12421 aatccttata tttatgaaac tttaaaagat gctggggtta aagttatagc ttcaagaact
    12481 gcaggggttg acatgataca ttttgattta gttaatgaaa atggacttat cgttacaaac
    12541 gttccttctt attcacctaa tgcaatagct gaattagctg ttactcaagc tatgaacctt
    12601 ttaagaaaga ctcctctagt aaagaaaaaa gtctgtgaag gtgattaccg ttggatagct
    12661 gaacttcttg gaacagaagt tagatctatt acagttggtg ttataggtac aggaaaaata
    12721 ggtgctactt ctgcaaaatt attcaaaggc ctaggagcta atgtaattgc atttgaccaa
    12781 tatccaaata gtgatttaaa tgatatatta acttacaaag attctttaga agaccttcta
    12841 aaagaagctg accttataac attacatact cctttacttg aaggaacaaa acatatgata
    12901 aataaagata ctctagctat aatgaaggat ggagcttaca tagtaaatac tggccgtggt
    12961 ggtttaatta atacagggga tttaatagaa gcactagagt caggaaaaat tagagctgct
    13021 gcccttgata catttgaaac tgaaggattg ttcttaaaca aaaaaatgaa tcctggagaa
    13081 ttaactgacc cagaaataaa taaacttctt tctatggaac aagttatatt cactcatcac
    13141 cttggtttct tcactagtac agcgattgaa aatatagttt attctagttt aagtagtgct
    13201 gtagaagtta taaaaacagg aactgctact aatagagtaa attagtattt tataaatata
    13261 ttttttcatt aattagctat tatctaacaa aatagccttt aatttcccaa atataagaga
    13321 gtcagctcag tatatattga gtagactctc ttatattatt ttttatatta aacttgtact
    13381 cctcttattt ataccaaatt aaatttatat taacttactc taactactcc tactctatac
    13441 attttaccta tttttacttt tctaattata tacatttgaa tgggtacaat ctgtatttta
    13501 caaaaaaaac acctaacaaa ctatgaaaat tgtatgatta atattaatat atttataaga
    13561 aaacataaca attatgttag ctctggattt ttagggaggg agtatattgg aaaaaatgaa
    13621 taaagttact tctaaaaaaa ctacctatat tgttacttca gcattatttg catccataat
    13681 atgcctgaca atagcatata tattacatat tccagttggt ggaaacaatg gatatgttca
    13741 tataggagat gcttttattt atctagctgc aactattttg ccaacaaact atgctatagc
    13801 tgcttctgca attggtgctg gtctagctga tttatctaca ggtgctgcta tctgggtaat
    13861 accaactata atcataaaac caatacttgt attatttttc acttctaaaa gtgacaagat
    13921 aataaataag agaaatatag ttgcttcggt tgtagcaggt atagtaggat tagttttata
    13981 catgtttgct gaaggtataa ttattggaag ttttacaagt gcatttgtaa tgagcttact
    14041 tggcttatta cagccaatag gaagttttat tgtttttata atcttaggta tggcacttga
    14101 taaacttgat tttaaaaaac gttattttaa ttaagaattt aaatttatgg agggaaaatt
    14161 atgaatatct tatatacaat tgaaaatagt atctatgtaa atataactaa tacatgtcca
    14221 tgtagttgtg ttttttgtat aagaaacgaa aaagatgaag ttgcaaatag tggtagttta
    14281 tggttggagc atgagccaag tgtagatgaa gtaaaagaag ccttcaataa atacaattta
    14341 gacgactatg atgaaatcgt attttgtgga tatggcgaac cattaatgag aataaatgaa
    14401 ttgatagagg tagcaaagtt tataaaagaa aaaagtagca taaaaataag aataaataca
    14461 aatggtctaa gtgatttaat acataacaaa aaaacagcta ttctgttaaa agatgttata
    14521 gatacagtat caataagtct taatgcccca aataaagaag cttataatag agttactcaa
    14581 ccaaagtttg gagaaaaatc atttgactat atgttaggtt ttgcaagaga ttgcaaaaaa
    14641 tatataaaag aagtagcttt ttcagtagta gatgaaatat ctccagaaga aatagaagaa
    14701 tctaaacaac tggcaaaaaa acttgatata ccattaagag ttagacataa gaattagcaa
    14761 gtaaaattat aaaacattaa gaatcacctg aatggtcttt caggtgattc ttcctcttgt
    14821 attaacattt tacaaaatag atttcatacc acactaggaa tgtgtaaatc atccaaatct
    14881 ttctccaatt atcagagttt ccactaatgt agtcattaaa aatctcatta atctcatcta
    14941 tgttaaagaa tttatctgct atctcactat tgaatttatc tcggatatcc ttattatatt
    15001 ggtcatcagc catccatata cgaattggca caataaatcc taatttattt ctaaaagcaa
    15061 tctcttctgg taatgttttt gatgcagctg tacgaaaggc aattttattc tcttttcctt
    15121 tcactttata ttctgatggt attctggatg caatatcaaa tattcttgta tctgtaagag
    15181 gcattctgac ttccaatcca actgcagtac tcattttatc tatattaaaa taaatatctc
    15241 cttccaacca tatttgaata tctacatttg acatgttagt aagtgtatct agttcttctg
    15301 tttcttcata aattcctttt accacttcaa taggaagcac atcaggattg tatttcttaa
    15361 gaatttttct tttctcaccc tcattcataa tgtttgtatt tccaatataa aatgtcttca
    15421 aattctctcc ataacactct gccttatggt atatattata tccaccaaaa aactcatctg
    15481 ctccttctcc agagtaacag atatttgtgt tttcagctgc tgccttgcat ccaatagcaa
    15541 aaacgatagc agatgcatct ccagttggtt gctccatatg gtacattaca taaggtactg
    15601 acgcaaaata ctcttcaggt gtaattatat atctcgaatt tttacaccca agaatattag
    15661 ctgtctgttg tgctaatttt gattcatcaa aacgctcttc ctcataacca catgaacctg
    15721 ttttttctat atctgacatt gccaatatat aagatgaatc aacacctcct gataagaata
    15781 actctgcagt ttcattctct gattttacct ctggcataat tttctgaagt gttgtatgaa
    15841 tttcatccgt ccattcctca atagacttgc tgtggtcagg atgaaattca ggtttccaat
    15901 aacgaccaat acatactgtt ttattctgat agacaaggta atgtcctggc ataagcttct
    15961 ttactccacg gaagaatgta ttttcacctg ctacatatgt gaaagacata taaatctgta
    16021 acatgtcttc atttaactct ttcacaaatc ctggttgctc cataatctta cgaatagatg
    16081 aaccatagag aagcttccca ttttcagtct cataataata gaaaggtttt actccaaact
    16141 ggtctcttag gcagaagagt ttcttttcca cagtatccca taatgcaaag gcaaacattc
    16201 catgcatgtg atttgccata tcatatcccc atgtcttata tgcttccact aaaattgctc
    16261 gttcacgctc atctctacat aatgaagaat cgattccaag ttcttcacag agaactttcc
    16321 agtttcgaat atgtccattg tattctagaa tttttatcat atatgtgtct tttcgtgtta
    16381 aatacttttc ttctaaattt atcatatgtg tatcctttcg tattaaaaca tttaacttct
    16441 aaatttatta aatgtttata tatatttatt cacttataat cactgaaaaa tcgacttttt
    16501 tcaaagtaaa ttctttttga attagtacta atctgctctt tattaatggc ataaatatga
    16561 ttatcaagta ttatcagtgt tataacattg aattttttat tcttcataaa tattgccccc
    16621 tttatattac caactaaata taatatatct tatgttactt acatattctt taagaaattc
    16681 tgaagatttt ataaagtttt ttgtattata attaattaaa aataaaattc tagttataaa
    16741 acatattttc cattaaacaa aaaaatagtt aaaataaatt cataaccaca taaacttatt
    16801 ttaactattt gtatatttta attataaata ttaacttaaa tttttaacag gatacactca
    16861 taaaataaac ataatgaaca acaaaataat atgtctcagt ttctttatat actttacctt
    16921 ctttcaattt tctaccatgt agacgtataa gataatatta gtaattcact ctattgctta
    16981 actcgtgcga tatggacaac caagaaagct atttcctcat ttgttaactt ttttccatat
    17041 ttcttttcta aaaaatctct aacttttaat gcaattaaca tttcttttgg atttgacctt
    17101 ttcatttgat taaataataa atcatcacca ctgcttaaca tactatctga aaaaaatctt
    17161 tccacaaaaa attttatatg tgttataaat ctcatataat gcatactctt tttatctaag
    17221 gttctattca aagaaaaaac aaaaatatta attatttctc caattacttt ggcatactta
    17281 atcgtatcat atgaatttcc atctgaagcc atagcatttg caaaatggaa agcaatgtta
    17341 gctgcttctt cctctggtaa ttgaatgccc aatctctcct ctaccatata aattgcaacc
    17401 attccaacct taaactcatt tggataataa ttttttattt cccaaaatac tcgatttgta
    17461 atttttattc ctttacgcat cctttcaatt gcaaagttaa aatggtctgc taatattaag
    17521 tataagtttt tattaaaaga tgagttcaat aacttttctg cctctactat tatttcctgt
    17581 gttatcttta aaatgtcgac aggaatatca tccattaatt ctaaaaattt ttttgatttt
    17641 gtattttcaa cagggacaaa catttgatta tcattggaac cacaaatata ttctcctgtt
    17701 tttttaccat atccaattcc tttccctagc aaaataaatt cattatactt tgcatcatga
    17761 actaaaacaa cgctcgagtt caaaactttc tttattatgt agttcatttt atttgctcac
    17821 cttctattgg tcatttaaaa tctatactat tattttcaat tactttttta taccaataaa
    17881 aactatcttt cttatatcga ttatatgtcc cctttccata atcatcagca tccacataaa
    17941 tatatccata acgttttgac atttgtttcg ttgattcact gaccaaatca atacaacccc
    18001 atgaagtgta tccccaaagt tcaacgccat cttcgataat cgcatctaac atacatttaa
    18061 agtgttcttt taaataatta attctatatt ggtcatgaac ttttttatct tcagttaaaa
    18121 tatctttagc tcccaatcca ttttcaacta taaataaagg ctttctgtat ctatcatata
    18181 attcaatcaa agatatacgt agacctattg aatcaatttg ccaaccccat tcactcattt
    18241 ctaaataagg attttttaca gctaataacg tattcccagg tgtaatatct aatccagttg
    18301 tatcagctgc ctcacaagaa gacatatagt aagagaatga aataaaatct actggatact
    18361 ttttcataat ttcatcatca tgttcttctt ttgctatttg aatgttatta tttttaaaat
    18421 acgaaagtaa atatactgga tactcaccaa aaacctgcgt atcactatat gcataaatac
    18481 ttctcatttt ttgttgagtt gccaaaacat cttctggtct acatgtatat ggataatacg
    18541 ttaattttgt taacatacac cctacttttg aatttggaat aatctcatgg caaatttttg
    18601 ttgcaagggc actagctaca aattgatgat gcatagcttg aaaaataact tcctcaaagt
    18661 ttttatcctt aaaacggtct cgaactaaac caccagtagt gtacggatga cgaatcatag
    18721 aatcaacttc attaaatgta agccaatatt tcactttgtt tttatatctt tcacagatag
    18781 tttctacata cctaacaaac atattgataa cttgtcgtga ataccatcca tcatagttta
    18841 aaacgatatt taatggtggt tcataatgtg acatagtaac aagtggttca attccataac
    18901 ttatcaactc atcaaataca tcatcataaa actgtaaacc ttcttcattt ggctctttat
    18961 catctccatt tggaaaaata cgagaccaag caatactcat tcgatatgtc ttaaatccca
    19021 tttctgccat tagagcaata tcttctttat agtgatgata aaaatcacta ccatgacgtt
    19081 ttggataatt tacttcatct tcaggatgtg ctaatccttc ttctatatct tttgttgtga
    19141 tttcattatt agatttatag tctttcacat ctgcatcaaa gtgtgccttt gctacatctg
    19201 atacagacca ccctttacca cctaaattcc aaccaccttc aaattgatta gcagctgtag
    19261 ctcctcccca aagaaatcct tctggaaact ttctcatatt tatattcctc cctttacatc
    19321 aaacaagata cttccttttt ttacattgcc ataagactgg tttaacactt tataagcata
    19381 atctgctcca ttattgttta caatcataac agttgaatct aaattagcat gtgagatttt
    19441 gtctaaatca aattgaatta ataaatctcc ttcttttaca ttatcgcctg tcttaacaaa
    19501 tgttttaaat ccatctccat tcatacttac agtatttatt ccaatatgaa tcaaaatctc
    19561 agccccattt tttgttctta aaccaattgc atgttttgtt tcaaataaca tcacaacttc
    19621 tgaatcacaa ggtgcgtata aatttccatt ggtcggtata attgcaactc catctcccaa
    19681 agtcttactt gcaaatagtt catcattaac cttacttaaa tctattactt ttccttctac
    19741 tggagttact aagatattta cttctttttc ttcttctagc tcttcttcaa caacatctcc
    19801 aattgatgac tctactgtat ttgtatcttc cttccaaata atcagtgtaa taataaacga
    19861 gcctaatatt gcaataacaa aaccaatact cgcaaaaatc aaattgtttc cattgtttgg
    19921 gtcaataaac atactcatac tggcaagccc tggtccaaca attacaaatc cttttactgc
    19981 aaataatcct aaaaatgtac cagaaattgc acttgagaat acaacaccta acattgctct
    20041 tttatgttgt aaagtaatac catataaagc tggctctgta attcccatca aggcagaaat
    20101 tcctgcagat aatgctgttt gttttaatgt ttcatctttt gttcgcaagg ctactgcaaa
    20161 acaagcacca ctttcagaaa tattgtgggc taatgaagat gtcatatata aagcttcata
    20221 acccaacttt ccaattgtat taattgaata aggtattagt gctttgtgca ttcctgttgc
    20281 aaccataaat ggaagaaaag cagcaagtaa tcctacaact aagaatccca ttttgttata
    20341 taagaataaa ataatggttg taaaaattgt accaacgtta tatcctaaag gacctaaaat
    20401 agttagagta attggaacag taattgccaa agacatcata ggaacaaaga aagttcgaat
    20461 tggttttggt gaatacttgt taaaaatttt ctccattgtt gccaaaaaag acacacataa
    20521 gatagccggg aaaacttgtg cattataggc aatgtttgga attgtaaatc caaatagttc
    20581 gacaccttca cttaaagcag ttgttgttgc tggaagcaat aagtatccta cagcggcaat
    20641 agctactaaa cgattacatt tcaatacatt ggcagtagtt acagctacca taagaggtag
    20701 gaaatagaat gttgcatctg aaatagcaac taataatgta tatatagtag aatctgattt
    20761 taaaatatta aacattgcta ataacatcaa cagtgatttt aaaataccag ctcctgcaat
    20821 agcaaaaatc agtggttgaa aaatattaat aataaattct ataaatcttg ttcctaagtt
    20881 tattttttct tcagttttta cagtactatc atttgtatct aaagggcaaa cttttaaaat
    20941 ttcatcatac acatcaacaa cactatttcc aatgacaact tgaaattgtg ccccattaac
    21001 tatactcata acaccttgta ctttttttaa agcatcctga ttgactttac ttctatcaat
    21061 caacttaaag cgtagtctag ttgaacagtg ttctaaagct aaaatatttt ttgaaccacc
    21121 aacttgttca ataatgtcaa tggcagtttt tttataattc atcttgtaat ctccttctcc
    21181 ataatttttt atgaatggcc attcaagatg caaaaaaggc agaacctata taaacacctt
    21241 gaaaaatcaa agcaatatat tcgatcctgc ctgcattacc agtaacatgt cttctattta
    21301 tactattttg tattattata ttaacatttg cctaaaagaa ttgtcaatac ttttttaaat
    21361 tttctgatac taactaatag cacctttata attcattttt tatgtcaatt aaagtaacag
    21421 tagccaccca ccaattagta tcaaaattga acctggtatt ttttctttta tattttcttt
    21481 gaatataaaa tgagcaagta ttaaagttat tatcatagat acttgagaaa atggctctgc
    21541 tatactaagt tctagattat ttaaagcaat taataatgct aaataagaat atccattaat
    21601 agcaccactt aaaattgaaa gccccttttt attactaaaa atctcacaaa ttattttttg
    21661 tttcttttta aatgctaaaa agataaataa atttaaacct acgaaaaaat acagtatagt
    21721 tgaatataat ataggagata cttgtacaaa aaaagcctta tccaatactc ttcctactga
    21781 ctgcaaaaat atgtataaaa acattaatct acatggtaaa ttgttaaaaa ttacagagac
    21841 attctttaaa aaagagctta ctttttttaa tataaacact ccaccaatca taattatgat
    21901 tcctgcaact tttgctaaac ttaaaccttc acctaaaaat ataactgata aaagcagtaa
    21961 aaacaatgaa tttaaactat ttattggagt aacaagtgaa acttccccag ttgctaaaga
    22021 cgttacatac gctactgaac caattgaata gactaaacta cttatataac atggtattaa
    22081 aaacgaccaa tcactaactc tatccattat gctaaatgga agtaaacata ctccccctat
    22141 aaagaaaaat agaaatgatg aagctatatt tttataaata tctccttctt catcacctaa
    22201 taatcttaca actactcttt caaaagctaa tagcactact ctaattaata atgcaaaata
    22261 agataatatc atttttgacc tcgcttaaaa attaatccga cttattgtta tattaactgt
    22321 ataagactac catataggta agtctttggg attttttaat attttatgtt taaatacagg
    22381 tacattaagt ttttcaccta gtttacggca ttgctcttta taggtacctt ttaatttatc
    22441 atgaaaaact atacaatcaa ttccaccttc aatactattt atacactttt ctagtttctc
    22501 aaatcccgat tcatcatcat acattccact tacaatccat tgatttggca atacatgtcc
    22561 aattgatatg ttatattctt tattttttat aatatctgag aaagatttct caaaatgtac
    22621 ccctccaaca cataataaag tcttcaaagg ttcatcacaa tcaaatactc taattaatga
    22681 ttttgccaat acctgtattg ctatactatt attaaaacta tcactactac ttcctatctc
    22741 aatatccaac ataggtacag aatattctgt aattaattta gattcttcac catatgttgt
    22801 tccagaccag tgagttgctt ctgttaatgt agtaaattca tcaagtagat tttcattttt
    22861 tatatcctca atagcattga ttagattttt aaagtatctt ggatttgaat ttccaaattc
    22921 tcctgttgga acatctccaa ttgtatgagc tgttaggata tgttctggag cattttctcc
    22981 ctcatgccaa tttacaactc ctgcaaaatc ataatctctg aaatgtctat ttaaaattgg
    23041 aagataatat ttataattat gacttattac atcttttgtt tttacaaaat gaaataagtt
    23101 attgttttta tccttaaatt ctaatacaaa attatcatca ataacaatat cagtttgatt
    23161 taaatccatt atttcttcac aacactttat cacattactg gctactgggt ctttctttaa
    23221 atcactacaa aagaaaaaaa ctgctttttt attattcatc cataaatcac actcctataa
    23281 cttaaatata atatatcttc atacctaaaa tcatctaaat atcactctaa ttccattaaa
    23341 ttatttatat ataatatact accatactca ttttagctat acctttgcct gagtttctat
    23401 atatatgtga tacatcagct ttaaatctta tagaatttcc actagataca atgtaatctt
    23461 ctccatttat tttaatggtt acttcgccac taaaaacagt tataaactct tgtgttcctg
    23521 gaagttcagc atttgaatct aaatttccac cttcttctat ttcaatcata aatatctcaa
    23581 atcttctttt ggagtcaaat ggaaatattg gataacttat atactttcca ttatcttcaa
    23641 taaaatggtc tatatcactt ttttgaatca attctatgtc actttcctgc ctctccatca
    23701 atgatgtaaa tgagattttt agtccattag ttattttctt caaagtagat atagtaggat
    23761 ttacctcaca cttttcaatt tgagatagca tactcttact tacaccacta agttgtgcaa
    23821 tcttgtctaa actaagatgt ttttctttcc ttatcttttt taaattttca gcgattattt
    23881 catttaaact ttgcataaat accccctaat acatactaat ataagataaa ttattttgat
    23941 tattaaataa acttagtaat ttaatagaaa ctttttatcc attatactgt acattatgtt
    24001 taatatacat tacttttttt agaatgtaaa tagttttctg aaattttgtg aaagtgaaca
    24061 aataaaaaac tagtaaccta tatttttaca aggctactag cttttattat aataatattt
    24121 cattttaact ataaaactta gatgcaccta taagctgtct cttagaaaca atcttagcta
    24181 ggtttgctaa tgaagaaatt tttatatctt taaaagaaac taaaaataca aacttaaaat
    24241 ctgtaaattc ttgatttata ttgtatatat caaaataaca tctcaaatta tcaaataagt
    24301 aattatcttg taagtctgct tctatctcat cagtagcatc ttttaaatac gctcttacat
    24361 cttcaaataa aacactgaaa taagactcat ctatttcttc acctaactct tccaatattt
    24421 cttctatatc taaatcatcc atatcaaaag aatttcctgt caactggcaa tcaaatacca
    24481 atatattttc ttgatttata gtatttgata tatcttgtac atattcgaag tctggacgta
    24541 attctaaaat gtcttttatt tcactgctct ttacatggat ttttcctttt ctattttcaa
    24601 tttttaaatc tatcatatgc tccccctttc aatctacaaa tctttaaata ccttgtttta
    24661 taatcttttc aatatctatc caattactaa ctctaactat attttgatgt ttaacatctt
    24721 tattatagtt agtatccaga agtattactt taacaccatc atcagctagt tgcactgagt
    24781 ttaaaggatt atcttctata aatatgtcac aactcagttc tcttgccttt tcaactttat
    24841 aatcacttcc taataagtaa acatctatat ctgaaaatcc ttgtctcgat agccaatttt
    24901 tagttacatc agttaaacac tcatgtctag ccgttacaaa agataaatta tgtcctttag
    24961 ataatgtgct aattacctct gtagcaccct ctacaatctt tgcttcatca tatgagtgta
    25021 tatacttatt attaaactcc gcatacacat ctcttattcc cgaaccatac aattcttccc
    25081 aattatgtgt tatacactct gcttcagtta tatttttatt aaagatatca tttaggtatg
    25141 gaagaaaatg ataagggctt gttattgttc catctatatc aatacatata ttcaatttgt
    25201 tcatttttac ctccatgtaa catttattga tttgattaat caaatattat agcacagctt
    25261 taattataaa tcaaaactct ggatatgact atacctatat aataccaaaa agcttgcata
    25321 tttaagcaag cttttcgtaa attttacatt tttaactaat atataagttt ttctaaggtt
    25381 ggttccactc caaattgtga tttcagttct ttatattctt ttaatgcttt gtcattattc
    25441 gttttagttt ttatcgctct tatcattaaa ttttttggtg tatcaagtgg agatatgtat
    25501 tctactacag aagtatcata tccattgccc tccaataaca atgttcttaa accatcagtt
    25561 atcaaatctg caaatctagc tttaaataca ccatgtttta atattggttc catagcttca
    25621 tatctatatt gccctaataa ctccttatga caacatggta ctactactat agcttcagat
    25681 tttgctctaa ttcctagacc tattgccata tctgtagctg tatcacaagc atgtagactt
    25741 attacaaggt caacatccct attaggtgta taattagtca aatcctcttt tataaatgac
    25801 atatttttat aacccaagtt tttagccata ttttttgatg cttctataac tacatctgaa
    25861 taatctattc ctataaaata acagtttttc ttcaatactt cttttatata aaaatttaag
    25921 acaaagctta agtaagattt tccacaagca caatccaaga tagttataca gtctttatcc
    25981 tttatttctt ttaaaatact atctatcaat tcaacaaaat ggtctatctg attgtatttt
    26041 cttattttat cattttttat cttaccatct tttgtaagta ctccaatttc ttttaaaagt
    26101 gcatttgctt gtcctacttt tacataataa tctctgtttt ttatttgaga tgccgtaaat
    26161 tcatctattt taggtacttc ttctttatta tctaaatatt ttacatttac cttcttattg
    26221 tctccttcaa ttacaacaat agttcctcgc tcaacatatt taaatactaa tccatcataa
    26281 ttttctgcct ctttagaaat attcttaagc aactcattaa acgtatataa atctgatttt
    26341 cctttaaaat taaatttata tttattatct tcctctattg caattccttt aaactctttt
    26401 cttccagatt taaaaatcac ctctaactca ataaaaaaat gcctattatc aaggtttctt
    26461 tgagtaatcc ccataaaaaa catatttagt tttcctatac tctgtttatt catcataatc
    26521 tcccttttaa cttatatctt taaatcttat taattaatat tatttgtttc tgaattattt
    26581 atttcttctt ttaaatcgtt caatctattt ttaaaacttt ctatctgctt atctgataaa
    26641 tcaagatatt ctgttatctt ccctatatat ttagggcttt tagtatttat taatttcaaa
    26701 gcactttcca tagatttttc tctaagctca tatgctttct ttacgtcatc tctagcatta
    26761 ctcaatgttt ctgtatactt ctccttagaa agttctggaa tctgcatatt ttcatattct
    26821 tttacaactt ctttacactt gtttctggca tttgtaacat ctttttttat actagataat
    26881 ttagttatat tttttgctat atccttagtg taaggtatac attctctcat tggaactaaa
    26941 gctgctcttt ctatattata aatttctttc ttaaaaattc ctatactttc catatctatt
    27001 ttttttatat cttcactatt tttttcttta cttgtatatt tattattttc ttttgtatta
    27061 tcttcttgtt tttctgattt attattcact gaaacattac tatcagaatt attcttttct
    27121 tttatatcat tacttccttc ttcattactt tctttatttt gtatatttct atcttgtttg
    27181 ttgtttaaat ttttattatt tgatatttct tcattctttt tattatcctg ttttaaatcg
    27241 gtactttctt tttccttaaa atttgataca tacttttcat catatgtctc atcagaaata
    27301 taattgtgat aatacataga ctcttttatt ttattaagtc cactcatata aatattactt
    27361 atcattattg ttgtagctaa taccacataa atactactgt agatacaaga cctcttaaaa
    27421 ttcttgtaat ttctgaatat cactactaaa ggaataagat ataaaaatat aaaaactaat
    27481 atccacctca taagtcgtgt ctcctttctc aaaaccgaaa tccctcaaat atttattttt
    27541 aatcatgtat cttatagtat ttaccaattt atgtttttta atcgtgaact tttattaaat
    27601 taaattctgt atagtcacaa gatgctaatg tatattctac tccatttcga atccccttca
    27661 atcccatttt aaaagattct ttaccatgca agtgaccata aatcaccttt tcaacattat
    27721 attcttcaaa taactttgta aataaagatt cttccaattt atcattcgta ggaggataat
    27781 gagtaatcac aattattttt gagtgaccac ttttacgagc agattctaat gatagtctaa
    27841 gtctatgctc ttctctttta taaacttttt catcagtctc atcaaattta acatcattag
    27901 gacatatcca gcccctacct ccacaaattg cataatcttt atattcataa aaatttgtct
    27961 gaataaaacg catgtcttca tatagcttat ttaaacttgt aacggttgtc caccagtaat
    28021 catgatttcc ttttataagt attttctgac ctggaagttt gcttattata tctaaatctt
    28081 ttttagcttc cgataaatta attccccaag atgtatctcc tagtactaag accatatctt
    28141 cttccttaac aacttctttc caattatcta taattttctt ttcatgacca tcccaattac
    28201 ttccaaagat attcattggc ttattgactg atgttgaaaa atgtaaatca cctatagcat
    28261 acaaactcat aatatcattc ctttcttaat tacactaaat aggctgtctc tttttagaaa
    28321 ttattttcca ttaagaggca gccccattaa tatttagcaa attttctaca agtagttttt
    28381 tactgaacta ctttatcatc taccttagta tccttatatt gctctagtaa tatatctatt
    28441 tcttgtttta attccaaaat ttcagttata tttttatctg tttcagttct atcaagtttt
    28501 ctttggtact gcatagcttt atgtgtatca cccaagtcat ataactcttg tattctattt
    28561 agagtatctc taatagctat agacttcatt tggtacatag cctgagcttt cattatgtcc
    28621 tctcttattt cactcatttc ttggtctaaa agaaaggcag catcagatgc tcttctaagc
    28681 ctttcagcaa gagtctcagg tatgtaatgg tcatatttat attttaatga atgttctatt
    28741 gtagcccaga aattcattgc aagagttctt atttgtattt cacatataat ttcctttgaa
    28801 cccgcaatgg agtttatagg gtattttatt ataacatgat agcttctata accactatct
    28861 ttgtaatttg taatataatc tttttctcct attatagtca tatcatttct tacttttatc
    28921 aaatcaacta tagcatatat atcctcaaca aactggcaca ttattcttat accagcaata
    28981 tcatcaattt cagtttctat atcttttgca tttatccttt ttaacttaga tattatggaa
    29041 gatatttttt ttgttctgcc tgtgacaaac tctatgggag aatattcacc ttttgctaaa
    29101 tattcttttc ttatattttt aaattttatt ttcaattcct ctactgcatg ttcataaggt
    29161 gctagtatct cattccattt ttcgtattcc atattgctca ccctttattt gttttttatg
    29221 accttcttta ttttatcata atttattttg tttttgtata gtaaagcaat tctccatttt
    29281 ccaatatata ccctatttct tctaaatcaa ctaagtaact tatgacagat actaacgaag
    29341 atttaaaaaa atgatactct ttataattat tgcttaaatt attgttattt ataatgtttt
    29401 ttaataaaat ttctaaagat ttcggttcta caagcaactc tcttatttga tataaatatt
    29461 tttttaaagc attcaaatgt ttttctatta atttataaga atcttctttc gatataactt
    29521 gcttgccatg ccctaaaact aagtactcaa aatctatatt ttttaatttt tctaatgaat
    29581 ttatttgttc ttgtatatca tatagaaaca agaaatcgta ttttgataga atttcatctc
    29641 ctatcaataa atcgccaaca aaaatcacat tatccttcgt caaaacagct atactaccag
    29701 gtgtatgacc ctgaaactca attatatcaa acatttcatt gtttaattca atttttccaa
    29761 cttctataga tttatctatc tttatatcat ccaacatttt attttttaag atattatcca
    29821 taaatacatt gctctttccc ccaacaatat actttgaaaa caattctgga ttttctatat
    29881 ataatttgtc gtattcagat gacattatac acacatcttt ataatattct ttaaattgat
    29941 tacaagctcc atagtggtca tcatgaccat gagtatttat aatatatcta acctgtatat
    30001 tattttcatc taatacttta tttactctcc taggtcttga accacataac cctgggtcta
    30061 tcataagtgc tgtgttatct tcaaatacat atattcctgt attcgtgcca ccttttataa
    30121 aaaaggtatt tccttttact tttgtaagat tcaccttcct cacctcattt tgacaatatt
    30181 tatgatacaa tttattactt actaatataa aactatacaa gaacaattct ttttattcta
    30241 tctatagttc tttttcttat tttgtattct ttagatatcc ttattttcac attatatgct
    30301 aaatttctat aaagtaatga ctctataaaa tattcaacta tacctctatc cctaaagtct
    30361 atatctatat ttccacttga ataaatattt gagtctaata tcataagctc atcaaaaaag
    30421 cttaatctct tagatttact taaataatct ttatttggaa taaatctatc acaataatct
    30481 atcctgtaat ttactacttc atcatttatt tcaaatccat attgcttttt cattaactct
    30541 ctatagttat tatttttctc aataacatta tctaaatttt tattataatc ctcttttttc
    30601 caatgtccaa acatcctaca atttaatggt ctaacttcat atattagaca tctattatta
    30661 gtatctttaa atggacatgg gttctttctt gtatactcct caaaataata atctaatatt
    30721 ttacttatac agcttttttt taaatcaact ctatcttcaa gataacaaaa tatattcaaa
    30781 aactcaatta aatttatacc tactgactcc atacaacaat ttccacatcc agaacaattt
    30841 cctactggca aggacttata tacatcattt agtttgtcaa agagcttatt tttaatggaa
    30901 taatctatac aatttaaaat atctttattt tttatactag tcattattat tactccttgt
    30961 tataattatt aagttaatac aaacaattat tataacatat tttttaaatt taatcgcata
    31021 tggaggtatt ttatgaatag atatacaaaa ataattaata tgatgggaag ttattacaca
    31081 aaagactttg aaaaagaaaa aaagaatgta ataaaagtta gagaagttaa agaagataca
    31141 gttagaaaat ttttcttgca aggtgactgt gaagttcttg tagtatttga agacactggg
    31201 aaagaaatac ttattgatga cttttctcct gaagaagata tcaaaaaata tttaggaaca
    31261 aaatttataa ataaaaaaag atagttatca aaaataattc taaaattaaa atttaataaa
    31321 tgtacagtta taattctata taattatagt taaaagttat cttttattgc ttttttagac
    31381 tttaagatag ctttttttct attttttgta aaataattcc ataattcaca ttaataattc
    31441 acaaaatgat ataatataac aaatagataa attttaaatt tctaaataca taattaatat
    31501 tttgcgaggt gattttatgc aaatttattt tagagttaag gctgttggca aacgcaaacc
    31561 tatgttagaa cttacccctt ttgatgtatc tgacaacatc aattgcctaa aagaagctat
    31621 ctctgaaatt gtatctaaaa atgttcttga atataatgag aaaatcccag aaaaatcaat
    31681 aataaacttc ttaactaatg aagaaattga atctcaagct gatattggaa aagttggatt
    31741 tggctctatt tacaatgaga ataaacaatc tgtagaaaag gcaatagaag tagcgttaca
    31801 ggcatttgaa gatggaatct acaaagtgct tataaatgaa gatgttattg aaaaactcga
    31861 ttcccctata aatctgaaaa gtggagatat atttactttt ataagactta ccttgcttgc
    31921 tggaagaatg ttttaaaata aataatttgg aggtacataa atgttagaac gtactagagt
    31981 agaaaaaaat cctaaaataa ttgaaaattt taaaaataat tttactaaat cttcttcaaa
    32041 acagtactac gacttagcaa aatctctttg ggactgcata gaaaatagtt catactatta
    32101 tagagaacct gaggacaaat tcttaaatat gataaagaaa tactacaatt gccactacta
    32161 cgaaattaaa aatatggacg agctcctttc tggaccttta aaaaatgcat tagaattaat
    32221 atttacttct gaacaagtag aagaactttg ccaattaatt aaaagaaaga tggattatac
    32281 atattcagga ggatattatc gtaaagggta tcgctcaaat aaacttgtgg attattttag
    32341 aggtattata aggtttattt caaactatgt tgatttaatt tattatgatt tttcagttat
    32401 agattatctt actcttccaa ataaggtctt gtactatgac tctataatga gtgataaaat
    32461 agcactagaa atagacaaag gaaatcaaaa agtaacaagt gccttagaag aagtaatatt
    32521 tggagaaaat caaactgctc tacttacaag acaaatgata attggtatca tgaagagtca
    32581 tagtgataaa tgctatgaaa tgctttctaa acttcttttg gcagccaaac aacaagaagg
    32641 acttagacag caaattgtag agagtttaga tgagggtaca atttctgcat caatatacat
    32701 gttaaaaact attttggaca acaatttaga gcgatttagt tctgttataa gagccttgga
    32761 tacatggaca ggacttggtt tttcagacca aaaacctgga ataatacgta aatgtttaga
    32821 actttcatat aaatcattga ctgatgaaaa gttccgtata gaatcaatta atagcaatga
    32881 taatcttgaa atttattttg ccttatgggc tactgcaact tacaacatat atgactctta
    32941 ctctcttatt gaaaacttac tttcttgtca ggaaaaatat aaaaaacttg tagctcttta
    33001 ctttttatcg catacagaaa gtacatattt taaacattct atagcatcta aaaacattaa
    33061 gggtgatgat ttagagatac tagcatgggt aattacaaat ttctatgtag aaggttctgt
    33121 tggctactac tatagttggc aaaacagaga aactaatttt gacttgtcaa acactcctat
    33181 tgacaaagac tttgatgcta gaaaagaaca atttgaaagt ttaaaacata ctttagaaat
    33241 tttaaattca aagacaaaat cattttcagg aagtgtattt ccatggactt ggattgaaat
    33301 ttcttctcat gaaatactta aatgtatgat gactttaaca gcatacgata tgaatgctca
    33361 atttatagat gtgcttatgg aaaattgtca tcttatgagt tcagatttaa gagcttcact
    33421 tatagtcaat tttgtaaatg aaccaaagac agatagacaa cgtgaatttt tattggaatg
    33481 tttaagtgat aagagtgttt ccaatagaga aacggtattg agtttactta gaaagcttga
    33541 gctaacagat gtagaattag ataagataac caatctattg tctttaaaga caagctctat
    33601 tagacaaaca gtaataaaaa ttttacttga acaagatgat tcaaatttgg aaaatattgc
    33661 ttcttcactg ataaaatctt caaattctca aaaatgcctt ggaggtcttg aaattgtaaa
    33721 cttattaaaa gacaattctg atagacaaga actatataat aagcttattt tacttataga
    33781 ggatattgat aaatctaaaa agaatacatc tcaagttcaa atattaattg ataatttgtt
    33841 aggtaaagca aaaaatgatt actgcaaaga aaatggtttt ggaatatata accctgaaaa
    33901 caaagttcaa attccagaac aatttgattt taaagatgat tctaatagct catcaaagct
    33961 taataaaatt atttcaaata taagtttatc tactagtgag gattctgttt ctgtagcaac
    34021 aaaaaaagaa gcaaaaaaaa ttctcgatac ggatataaat aaaataataa aagtttatga
    34081 aaaatttgat gagcttatta ctgaaaatgc agattatgaa tatgaagttg aaagatggtc
    34141 aggtaatgta gacaaagtgc ttttaggtta ttctacttat aacttgactc ctattaaata
    34201 taaagtttct aatgatactc ttgataatta tccattggca gaactttgga gagaaactag
    34261 taaaaagctt gacttagatt acaaattaat acttgatatc ttattttata gtataagtac
    34321 atgtggatat aatgaaacag aaaaaagttg gttttcatct atatattcaa atgtccttga
    34381 ctctaaaaaa caaaataaaa tatatacaaa acttgaaaaa tttaaattta atggacttac
    34441 aagaaaactt ttaagagttt tactaaatga gtttgaccat aaagaaatat ttaactattg
    34501 tttagaaata tactataaac ttagaaactt attgactata gaacaatgta aaaaacaaag
    34561 agttgaattt actaaaaact attacagaca aaatgaatac tgccctgctt taaatgcccc
    34621 tattttaaac tattggcttg ataaagcaca ttcgtttatt tatgatgata tttcttttac
    34681 taagtttttc tacactacgt tttcaaatta tcagttgcta gaatataagt ttcctttcta
    34741 tactagcata aatgtgtttg ctcgtgcaca tgaattaggt ttaatgactg aagagcaagt
    34801 taatagagaa atgataagtg gatacaacgc atcaaatata ataagaacat taacaaatcc
    34861 tagatgggct ggtgacacat tagaaaagta cccttggctt aaagataatt taaaaactgt
    34921 tacaaaccga attatagaaa ttgaatcacg tagaggtgat atgccaacag aagtgtctca
    34981 tctagctaat aatatacaat actttgaagg tatagattat tttgtaaata ttttggtcgc
    35041 tcttggtaaa gaaactttcc agagaggata ttcatatggt agcaattatt caaaaaaaga
    35101 tgttttaagt tctctactta aaaattgcta tcctactaaa gaagatgatt caaaaaaatt
    35161 aaaaagttta cttaaaaata ccgacattac tgagttaaga ttaatagaat ctgctatgta
    35221 tgcccctcaa tgggtaaaca taattgaaaa atatttaaac tggaagggtc tgaaaagtac
    35281 aatttggtac ttccatgcac atataaatga aggcttctct gcacaaaaag aatcagaggt
    35341 tgctctattc tcccctattt caccacgtag tttcattgat ggtgcatttg atgtagattg
    35401 gttcttagat tcatataaaa ctattgggga agaaagattc aatatacttt acaagtcagc
    35461 taaatatata actagtggtg gtaactctca tagacgtgca caactctatg ctgatgctac
    35521 acttggtaag cttgataaag acatgttgat gaaagaaatt gaaacaaata gaaatcaaga
    35581 taaattgaga agtttctctt tacttcctat gaaaaaagga gacctaaaag aagcaacttt
    35641 ccgttatgaa tttattcaaa agtttgctaa agaaagcaag caatttggtg cacaacgtcg
    35701 tgaaagtgaa tcaaaagctt gtactatagc gctagaaaat ctagctagaa gtgctggatt
    35761 tggagatgta aatcgtatga tgtgggctct tgagactgaa aaactaaatg aagttgctca
    35821 tctatttaaa ccaaaagata ttgatggtac ttcaatttgg atagatgttg atgaaagcgg
    35881 aaaagcatct actaaagttc aaaaaggcaa caagtcttta aagagtatac caaaagctat
    35941 tgctaaacat ccatatgtac ttgaacttaa atctgtccaa aaagatttaa agagtcagta
    36001 ttctcgtgca aaacagagtt tagaacaagc tatgaaaaat gaaatagtat ttacagttaa
    36061 agaaattgcc aatatctata aaaatccagt tatctgccct ttgattaaaa atctagtatg
    36121 ggtatgtgat gataatattg gatatgttta taatgataag tctaagttct ttatttgcaa
    36181 tatagaaggt gaaacttata agttgacagc aaaaaataaa ttaaaacttg cacatccagt
    36241 tcatttgttt gaatctggta agtggagtga gttccaacat gatttattta gtaagcaact
    36301 tgttcaacca tttaagcaag tattccgtga gtattataga ataaattctg atgaaatatc
    36361 tgaaaaaact atatctcgca gatatgctgg tcaccaaatt cagccaaaga aaactgtagc
    36421 acttcttaga aatcagcttt ggactgtcga ttatgaagag ggattacaga aagtatttta
    36481 taaagaaaat atagtggcaa agatgtttgc acttgcagat tggttttcac cagcagatat
    36541 agagcctcct actattgaaa cagtagaatt ttttgataga aaaacttata aaagtttaga
    36601 attagcttct atacctccaa ttctattctc agaagttatg cgtgatatag accttgttgt
    36661 aagtgtcgct catgctggtg gtgttgaccc tgaaactagc cattctactg tagagatgcg
    36721 tatagcaatt gctaaagaac ttttattatt attaaaaatt aacaatatca attttgaagg
    36781 ctctcatgtt cttatcacag gtaatttagg tgagtattct gtgcatatgg gttctggtat
    36841 tgtacataaa aaagggatgg gtgctttgaa tatacttcct gtacattctc aaagtagagg
    36901 taagatattc cttccattcg ctgatgaaga ccctaagact gctgagatta tgtctaaaat
    36961 cttattactt gctgaagata ataagattaa agaccctagt atcttaagca acttataaat
    37021 ataagattta tctctaaaac atattgggct ttctaatttt ccatgaaagt ccaatatgtt
    37081 ttatattata ttttatacga attaatttat aactatagca aatttatatg atatcttcat
    37141 catacatatt gtatatcact gaaaattttt ttcttcatta aaacctttta accctataaa
    37201 atctgtatag aaaatctttt tctaaagatt tatttaaagt agcactttct tgaaaattta
    37261 taaattttat ctctaaagaa gacttattta taggtataac cttatgtata agtcttaaat
    37321 ttactatgta ttgtctatga gtcataaaga aattaggagg taggcgtttt tttaaatcat
    37381 caaagttctc ataaaatttt atcgtatctt catctctagt atataaatta atagctcttg
    37441 aatttttctc aaacatgact atatcatcaa aattaatcat atgtatctgt ttccttattt
    37501 tatatacaaa aagagtatct tctataaaat tattttttgc aattttatga gagttaatgt
    37561 ggtctattgc tatattaatt gaatcaagta ttttttcttt tttaaacggc ttaactataa
    37621 aatctatagg atgtacttta aagctctcaa gactatagtc agcaaaacct gttacaaaaa
    37681 ctatatgtat atctttatct atagaaagaa tttctttggc agaatcaatc ccatttttat
    37741 atggcatatc aatgtcaata atcaataagt ctattttctc actttttata aattcaattg
    37801 cttctatacc atccttgact ttcttaacat aatctacata tccggactct ttaactatat
    37861 ttgctatatc atctcttaca attttatcat catcacaaat caaaactttt atcacagact
    37921 tctctcctcc taactaataa tattttggta ttaaaattac aaattcagtt aaaaaatcgt
    37981 cactatttac aagtatacta taatcatact tatctagtat atttttaact agatataacc
    38041 caaaacctct gtcttgccct tctttagtgc taaatccatc caaaaatata ctttcgacat
    38101 tatgtatttt aggaccatta ttttttatgg ctataatata ctgaaattca tcttcatatg
    38161 catgtaatct tatatacttc ttttcctttt gtatagcaga caaagattct attgcattgt
    38221 ctattatgtt taatagcact gaactcatat cattaggttc aatctctaaa ttatccataa
    38281 aatcttggat atatacatca aaagatatgt tcttttcaag acattcctca tattttaagg
    38341 aagctatagc atctaaataa gatactttcc catatcttga attttttgat ttaaagctat
    38401 ttgatatatt cgttatatat tcttttgcat cttcagctaa cccagtattt aatagagaat
    38461 atactacttg taaatgtttt aaatagtcat gtttttgact tcttaatttt acgattatat
    38521 tgtccttatg atttatttta ctgtctaatt tttgtagctt atactcttgt ttattgttat
    38581 tgtctagtaa tcttataaat ttaaatccta tataaaagct taaaataatt aaaattaaaa
    38641 aaagtataat atttaatact ccttcaagta aaaaattata tcctaaactt aattgtatat
    38701 actcaatacc ctccatgaat aaaatccata caaaacacga tacaaaaaac gttaatattc
    38761 ctctttttaa tatgtctaat tctttataaa acctgtattt attcattata agattactaa
    38821 atataaacaa agttagtatt actataggaa atataaaatt attctccata attcccctcc
    38881 catctacact ttatatgagg attatatcat tttagaaaaa ttatgtaaaa agtcaaaatt
    38941 tacatgtaca ttaattaaac ttgcaaatac acatataaat ttgtacaatt aagtactcaa
    39001 aacttgaaga tacttacttt gatatatatt ttaaataaac atataattga tttagctaag
    39061 aaaggaagtg gtaaatatga aagataattt aaaaatagca ctaagataca taataagtta
    39121 taaagcaagg tctttagcaa ttgctctaag tataattctt gctacatcac ttattgttgg
    39181 tattggtacc ctctcaagaa gtgctcaaca agcagaggta gataaattaa aaagagaaac
    39241 tggaagtgat catgtatact ttaaagatat aaataaaaat caattagaat acataaagtc
    39301 tagaaaagat attaaaaatt taggtataac atctcactat ggctatacag atcctaatga
    39361 aagattagct ataaacctag aatatgcaaa taaaaattac ttgactaatc aatccaaact
    39421 tataaaaggt caccttccaa aagctagtaa tgaggtggtc gtagagaaat ggattttaaa
    39481 tagtctgggt ttaaaaccag aaataaatca gaacattact tttaaattat atcaaaaaga
    39541 aaaaccagag acatttaaag ttgtaggaat acttgaagat agacctattg agaaaaataa
    39601 agggacatgt gaaatttttt taaatctcaa tgaatcaaaa ttggataaat tttcttatgc
    39661 ttatattgaa tttaataatg gcattgatat aaatacaagc atagataata tagtaaaaaa
    39721 tactatgttg gatgagaata gtgttggaaa aaacaaaatg cttatagaat ctactaggga
    39781 aaatggtact ttagataact caagtaaata cactgcaatt actatgagcc tattttctgg
    39841 tattgtaata tatagtatct atgttatatc gatatatcaa agaatacagg aatatggtat
    39901 cttaagagct attggatcca ctaacttcaa gattttcaag tttatgtttt atgaactttt
    39961 catacttgct ttgatagcaa tacctatcgg tatatgcaca ggtattggtg gtgcacaaat
    40021 atttaatagg actgcaggaa atattcaatt tgaaggtaat gtaacagtta ccccttttgt
    40081 tattccagat aaaataatac ttttatcaat tggaagtata atactgacaa tactaattat
    40141 aagtttcttt acatatttaa agataagaag aatttctcct attgactcta taagaaaaac
    40201 ctttggaact gataaaaata taaataaggt caattctttg atatcaaaat taactttaaa
    40261 tatatcagta acaaaatcta tatctgctaa aaatatcttt aggaataaaa agggcttcat
    40321 tataattata ttatccatga gtctaggagg tataatgatc ataaaggaga attataaata
    40381 ttctttttca gatatacaaa ataaaaatgg tcaagaagaa acatatatga atgcagattt
    40441 tattctaaca aattttttct taaaactaaa tcaatctaat aaagctgatt ctttcaagga
    40501 tataaaagga cttaatgata atcagataga taaaataaaa aatataaatg gaattgacaa
    40561 agtcaaaact gccagcatct tagatacaag aatagaagta gataaattaa atggattaga
    40621 ttactacaat attattaatt caacgcctta ttataaggat tttcctctat tcataaaaaa
    40681 taagaatact ggaaaatata caatgaaaca aaagttaaga ggttacaatg atgagatgat
    40741 aaattcatta gaaaaatact tagtgagtgg gagtataaat ctggaaagaa tgaaaaaaga
    40801 aaacctcgct atattatacg taccacaagt ttctaaaaca aataaataca agctaagtta
    40861 tactcctggt acagaaacgc ctgctgtaga tataaaagta ggagatacta taaaggtcaa
    40921 atatccaaaa ggtgagatag atcaagatct ttatataaaa ctaaaagata attatgaata
    40981 tctagaatat gagtttaaag ttggagctat tgtaagttat ccttttgcag ataattacct
    41041 atattctgga gatcagggta tagatgtaat aacaagtaac gactatctaa aaaaactaac
    41101 tggtgtagat aaatataatg tagtttatgt agatattaat aaaaatgcaa atgtaaaaaa
    41161 gataaataca ctcttaggtg aaataggaag tgaatctcct ggaactacaa cagctaatat
    41221 gctaatggaa aaagaaaact ttgataagat gacagctagg gctctgactt atgcttatgg
    41281 aatagtagca gtaatgttta taattagtgt gtttaatata ataaataaca taagttataa
    41341 cttaacttca agaactagcg aatttggaat gttaagagct attggtatct ctgagagagg
    41401 atttaaaaat atgatactct atgagggaat attatatgga atactctcaa gtgtaattac
    41461 cattgtggta gggcttataa tacagtttag aatgtattac acgtataatt ttgtatcata
    41521 tggattggga ttttcaatag attacaaaat atatatccta gttgttttag caaacataat
    41581 tgtaggtatt ctagctacat atattccatt aaggaaaata aataaaatta gtatagttga
    41641 agctataaac attacagaat aggaggatta attatgccta tattagagat tcttaactta
    41701 ggtaagattt atggaaaaaa ggaaacagct gtacatgcac taaaggatgc aaatttaaaa
    41761 ataaataagg gtgaatttgt tgcgataatt ggcccaagtg gaagtggaaa aagcacattt
    41821 ctacatttag taggaggtct tgagagacca agtagtggaa ctataaaagt cgatggtaaa
    41881 gatatatgtt gcctttcaga taaaaaatta gcaaaatata gaagacaaaa agtaggcttt
    41941 gtttttcaac agtataacct aattccagta ttaaatgtaa aagaaaatat agaattacca
    42001 ctaaagttag acaataaaaa agttgatgaa gaatacatcg aagacattat aaatttattg
    42061 ggtcttagtg agaggaaaaa tcatcttcca aatcaattat ctggtggtca acaacaaagg
    42121 gttgctattg cacgcgcttt atctgcaaaa ccaagtataa tcctagcaga tgaaccaaca
    42181 ggaaatttgg atagtaaaac tacggaagaa gtcatggatt tactaaaaag ttctataaaa
    42241 aaatataacc aaacacttat aataataaca cataatgaaa atattgctag aaaagcagat
    42301 agaattatat ctataataga tggagagctt aaattaacac tctaaaacta tttatagaaa
    42361 agaggattta aatgttattg attttagata atttaaattt aaacttagat tttgactaca
    42421 gaataataag agaagaaaat gatgatgtag atatatttat agatattaat tatcgtagct
    42481 tagatataga tactgatggt tctaacttat ttaattctag aatacaattt ccatttgtaa
    42541 gagcattgat tctaaggata aataagaaca atcaatgtat gacaattcat ttgttaagag
    42601 atatagattt attctctgct tttgccaact ttgaagtgga ttatactgac tctataataa
    42661 atataaaaaa tcaaaatgag aaagtaattt taaataaatc tatcaaaaaa tagtaagggg
    42721 gccttaatag gccccaattt ttttcttttc taaatttatt atatcatgat aaataaatta
    42781 gtcaatagaa ttttctgaat atttttataa ttttttcata aagtttttta tatattatgc
    42841 tttaaaatta tatgtaataa aaaaattttc cgactaattt taaagttaat tgattaaata
    42901 cacatattcg aaattaccat taaattactg actttttatc atttccattc agaatttaag
    42961 ttataatcta ttatttatag ttacttctac gtttctctaa taaaactcta tttatattca
    43021 aatctaataa tttatataca aacccaatag aacctatgtt gtacaatgaa tattatttac
    43081 cataataaac ttttagatat atctctttta attcactcat caatgggtat ctaggattag
    43141 cacctgtaca ttggtcatca aaagcttgtt caaccataac atccaatgtt tctaagaatt
    43201 tagattcttc tactccagcc tcttttatag ttttaggaag tcctactctt gcctttaatt
    43261 catctattgc ttttataagg ttatctactt tttcttggtc tgtatttccc ttgattcctg
    43321 caaaagaagc aaattcagca tatctttgta tacaatcagg atatctgtat tgtgagaatg
    43381 cacccatctt atttggagct tctgcacaat tgaacttaat tacttcattt attaataatg
    43441 catttgcaac accgtgttga acatggtgga atgcacctaa tttatgtgct aaagagtgac
    43501 atattcctaa gaaggcattt gcaaaagaca ttcctgccat agtagatgcc attgccattt
    43561 tttctcttgc ttctttatca ttctttccat ttttgtatgc acgaggtaga tattcaaata
    43621 ttattttacc tgcttgtagt gctagaccgt cagctggttc agttcttaac atagatacat
    43681 atgcttctaa tgcatgtgtt aaagcatcaa cacctgatgc tgctgttaat cttggtggca
    43741 tctccatcat catatcagca tcaattatag ccatgtttgg cattaattca taatctgcta
    43801 atgggtactt tacacctgaa tcttggtcag ttataactgc aaatggagtt acttctgaac
    43861 cagttcctgc tgaagttggg atagcagcaa aatacgcttt ttcacccatc ttaggaaata
    43921 catatactct ttttcttata tccataaatc tcatagccaa atcttggaag tctacctctg
    43981 gatgctcata cattacccac attatcttac cagcatccat tgcgctacct ccacctacag
    44041 ctattattaa atctggttgg aaatcagcca tagccttagc tccttctctt gcacaagcta
    44101 atgttgggtc tggagcaaca tcaaagaatg tagtatgctt aattcccatc tcatccaaca
    44161 aatcagttag cttcttagtg tatccattat tgtaaaggaa agaatctgtt actataaagg
    44221 ctttcttttt atccataaca tctttaaatt ctcttgctgc tacacctaaa caaccttttt
    44281 tgaaataaac cttttctggt gctctaaacc aaagcatatt ctctctcctt tcagctactg
    44341 tcttgatatt aagtaaatgt ttcactccca cgttttcaga tactgagttt ccaccccaag
    44401 aaccacaacc aagagtaaga gatggtgcta atttaaagtt atataagtca cctataccac
    44461 cttgtgacga tggagtatta actaatactc tacaagtttt catagcattt acaaacttct
    44521 ctactctatc tggatgattt atagagtctg catataacga agatgtatgg ccatatccac
    44581 catctgcaac taatttttca gctttagcaa ctgcatcttc aaaactttta gatttgtaca
    44641 ttgcaagtac aggagaaagt ttttcatgtg caaaaggttc atttaattca acagattcta
    44701 cttcaccaat tattattcta gctgtttttg gaacttctac atccgccatt ttggctatta
    44761 catgtgctgg ttgtccaact attctggcat ttaatgaacc atcaattatt actacttttc
    44821 ctactttttc agtttcttct ttatttagga aatgtgctcc acggtattta aattcttttt
    44881 taacttcttc atatattttt tctggtacta ttacagcttg ctcggaagca catatcatac
    44941 cattatcgaa tgattttgat actaagattg aacttacagc catttttata tctgcactct
    45001 catctattat tgcaggtaca tttccaggcc caactccaac agctggttta cctgaagagt
    45061 atgcagattt aaccattcca ggtccaccag tagctaatat aaggtctgcc tctgccatga
    45121 caacattagt taattcaatc gaaggaacat ctacccaacc tataagtcct tttggtgctc
    45181 ctgccttaac tgccgcatca tgtacaactc tagctgcttc tatagtacag tttttagctc
    45241 ttggatgagg agagaaaatt ataccatttc tagtttttag tgctattagg gatttgaata
    45301 ttgcagttga tgtaggatta gttgttggta taactgctga taaaacacct actggctcag
    45361 caattcttgt aaaaccaaat gcttcatctt tttctatgac accacaagtt ttagtatctt
    45421 tataagcatt atagatatat tctgaggcaa aatggttttt tataacctta tcttcaacaa
    45481 tacccatacc agtctcttcc actgccattt ttgctagagg tattctttgt tgattagctg
    45541 cagttgaagc agctaagaaa atcttatcta cctgttcttg cgtaaatgtt gcaaattctt
    45601 tttgtgccaa tctaatttct tctaatctca ttcttaatgt ttcaacactg ttgacaattt
    45661 caggactaca tacttcaaca tttgattttt ctactacctt ttcttttttc tccatactaa
    45721 aaacctccct aaaataatta tgcatctcta atttttataa atcttaaatg caccatctat
    45781 atttttaact tatacttaaa ataattttat agatttcatc tctatacctt agattttatt
    45841 tattttactc tcttaggtca agaagttttt ttctgaatat tttgtcaatt tattttttaa
    45901 caaatatatt atttttttta cttttactaa aattttttat ctaaatgaga tatatttcat
    45961 ttgaataatt tacttcaac
//
LOCUS       DAMJYN010000027        45750 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.027, whole genome shotgun sequence.
ACCESSION   DAMJYN010000027 DAMJYN010000000
VERSION     DAMJYN010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 45750)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45750)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45750
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.027"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            101..433
                     /locus_tag="PC466_001573"
     CDS             101..433
                     /locus_tag="PC466_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE family protein"
                     /protein_id="HDF2768961.1"
                     /translation="MKVAYIFSSTNTHKILDKMIIPQLEQGTHGVDVLGMFFFMDNTL
                     FLSKGNPVGERLSKLHEKTDMIIMACDQCAIERGIENNLVDGATIGCFPNLYACLGSA
                     GVDQVITL"
     gene            595..780
                     /locus_tag="PC466_001574"
     CDS             595..780
                     /locus_tag="PC466_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768962.1"
                     /translation="MSEKYADKLEIKLYQAGKDFSYIKKYGIITKGTLIINQKKKYDR
                     LNKDTIERAIVEAINNN"
     gene            807..1892
                     /locus_tag="PC466_001575"
     CDS             807..1892
                     /locus_tag="PC466_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HDF2768963.1"
                     /translation="MNILEIVLNGVKDTIVASIVTLNGASGWLMISFILAGVLHNVLT
                     PRRFQKQLGNKKFSSLIKSTISGMFLPICSCGVIPLGISMYYSGAYLGPVLAFMTSTP
                     IINPIAVVLCLGLLGPKVTIIYLIAGFLVPFLVGFLGNCFGKEELSLYNDSEEEVIEL
                     EEEKRSFMENMIDGLKWSFGELALTISKYVVMGMVFAGFITTIFPNSIIQKYLGNPGL
                     LSLGSIAILACVMYVCAVGHIPFIAALVASGASPGIAITFLIAGAATNLPELISMFKL
                     IGKRTVIIYSVTLTLSSIIIGYITNLLLVNNNSVNLDATNSSIQLANKLMLNIPDSFE
                     YVCTILIILFAFKSTIPKMKEVIGNHA"
     gene            1885..2343
                     /locus_tag="PC466_001576"
     CDS             1885..2343
                     /locus_tag="PC466_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768964.1"
                     /translation="MLKKIVIISCIVVVLIILSKIVDDNIKEDASIPNVNKETLEYFR
                     KNYKEDIITCAEEDLNNDGKKDLVVIYKKSNNSNEMVVVVSDKNSHYITKPIPAPIEN
                     QTITFKNIDDKAPIEVIVSGSKNGNVGYAIYRVEGKKFVDLFGEDMDKCC"
     gene            2378..3469
                     /locus_tag="PC466_001577"
     CDS             2378..3469
                     /locus_tag="PC466_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF2768965.1"
                     /translation="MKLSKKIQALILFGVMGTSILTGCSSKPKEKEEAKAGKDDYTIT
                     VGYYNCDHMTAGPVAESAGIYKDLGLNVKTVGNGKVPEAMAAGKMDAGYIGTKGLVGA
                     IPKGSPITIAANNHTGGSEYLIVSKDIKEPKDLIGKKIATDMSDFLWTSDYGPETGLP
                     TDPSKYEVVNMDSDKDKYLALKTGKIQAFTSCDPWGSVAENDGAGKIIASTQYKEKAN
                     GKEYNCCSFSLNKNFIKEHPDLAKKLVLAHTKAIEYIYTNPAEAAKIFAKYYNVEEEV
                     ALRTIYKKTVGEGRTLTWKVTGEEYKNNLQMYKDLKALDDIPKYEDTIDTSLLDSCGA
                     DDFDKFIKEKVNPEFPEGMSYEDWKAKVL"
     gene            3474..3698
                     /locus_tag="PC466_001578"
     CDS             3474..3698
                     /locus_tag="PC466_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768966.1"
                     /translation="MENIKNIIILFIIILGSIFIIFFNFEDKEEIKGKLRIGVSDDTS
                     GFVINYMVNRDYFENIKVSDIMDIFTINDC"
     gene            3708..4271
                     /locus_tag="PC466_001579"
     CDS             3708..4271
                     /locus_tag="PC466_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768967.1"
                     /translation="MQWALSSEEIDIAIICKDAAKQYVNVNSGFEIVGTVVQNSDIFL
                     LSDNNPEKIGVIQNRDYQSELVKKYYKNVEVAPLLGTALAYGLESNLVDGVVIDCIKS
                     IGLEGKRKSTTKLGDYDTYVLVVSKEFKKSKAYSDFITLYNKSVDALKNKATFKKALK
                     EYRNIRNIDMEEISNWKLKFLKIKAID"
     gene            4232..4861
                     /locus_tag="PC466_001580"
     CDS             4232..4861
                     /locus_tag="PC466_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2768968.1"
                     /translation="MEIKISKDKSDRLTKKKTDGSMDILYKIILLVIIFLVWHFAAKD
                     IGSSLLLPMPVDVIKGFFFCVTDAETVTNLFITLQRVLKGFMYALLFGLPIGFIMGFS
                     KTFERVLSPVVDSVRQVPIMAWVPLTIVWFGIGDGPTIFLIAFSGVFPIILNTIQGVR
                     AISKDYYNAARSMGASPIVIFTNVIVPASLPDILTGSRIAISTGWMSVI"
     gene            4901..5038
                     /locus_tag="PC466_001581"
     CDS             4901..5038
                     /locus_tag="PC466_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HDF2768969.1"
                     /translation="MVQAQTLMHTDVLIGLMIFAALIGFIIDRVLKFINKILCRWRFA
                     D"
     gene            5038..5790
                     /locus_tag="PC466_001582"
     CDS             5038..5790
                     /locus_tag="PC466_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2768970.1"
                     /translation="MKLSVRDINKTFVNNRVHTKVLEDISMDIDDGQFVCLLGPSGCG
                     KTTLLTIIGGFQKSERGDVFINDKRVKKPGIDRAFIFQNYALFPWKTIRGNVLFPMKQ
                     QKIPKEKREEMLEELLVMSDLKGKEKLFPHQLSGGMKQRVAMIRALACNPEVLLMDEP
                     LGAVDFQMRQNLQEELERIWIKKKITALMVTHDVDEAVYMSDRVIVMSRDKGRIIDDI
                     NIDIPRPRIRGSQKYEEYKNKLTDTLSKCYEV"
     gene            5803..6288
                     /locus_tag="PC466_001583"
     CDS             5803..6288
                     /locus_tag="PC466_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768971.1"
                     /translation="MSQIEKYNSLDNTQQKIRISIMDMIIDKGSSVTLQEVTEYVSKK
                     LNIEKEYIERTLQYFIYENIMVVDGNSINFIYPVSALQTNHKVTLRDNRSFSAMCAID
                     AIGTSCTFNQDIKINSICSATGKEIEVIIKNEKIEYVNNPNLRVLHINLDKHLNWAAS
                     C"
     gene            6295..6444
                     /locus_tag="PC466_001584"
     CDS             6295..6444
                     /locus_tag="PC466_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768972.1"
                     /translation="MNFFWTKSDFDAWTNEAGLSDDEDIYCLDINEAIVESYKIFKLK
                     QKVLS"
     gene            complement(6580..7401)
                     /gene="yidA"
                     /locus_tag="PC466_001585"
     CDS             complement(6580..7401)
                     /gene="yidA"
                     /locus_tag="PC466_001585"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HDF2768973.1"
                     /translation="MYKLIALDIDGTILNTQKRITPEVFESIQEAKRAGAKVVITTGR
                     PLPGVKELLNQLNLTDEGDYVICFNGAIIQEVKSEKIIHDVEMTLDDFDFIYNNVCKK
                     YKTKIHINTMTNLITPNEAPGKYTLHEAKLNNIEVKYIQKDKIDESIKICKIMIVDEP
                     ERLEEIIQQLPKNLFNKYTIVRSAPFYLEFLGKTTNKGTALKTLCTNLNIPIENAIAV
                     GDEENDQHMIKYAGLGVAMGNARNSIKEIADYVTDTNNENGVAKVINKYILNKAI"
     gene            7893..9587
                     /locus_tag="PC466_001586"
     CDS             7893..9587
                     /locus_tag="PC466_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HDF2768974.1"
                     /translation="MKFSEFKYERPNYNSMKKEFLSCVEDINNSRNYKEQQKNIHKIN
                     LLRNKIETLSNIASIRYSTDTFNKFYKEEKNYWDEYMPLYEELNSHFYNAIVNSKFKY
                     DLIKEFGEQFFTIVEYSLKSFSKEIISELQEENKLCSEYTRLLASAEIMFDGNIRNLS
                     GMGKFMYSKNRKTRELANKAYYNFFEENETKFDDIFDKLVKLRDKISKKLGFEDFVEL
                     GYVRMMRSDYREDMIKNVRKQVLKYVVPMANELYEKQAKRIGLEYLSYIDEGVEFLTG
                     NASLKGDSRYIIQNGKRMYSELSKETNEFFDFMLENELMDLETKKGKGAGGYCTYIPD
                     YKSPFIFSNFNQTADDIDVLTHEAGHAFQLYMSRWIDMPEINFPTLDSCEIHSMSMEF
                     ITWPWMDLFFKEDTDKYKFTHLSSSIKFIPYGVIVDEFQHYIYKNPNVDKSKRKEIWR
                     FLEKKYLPHRKYGDNSFLERGCWWFKQGHIFKNPFYYIDYVLAQICALQFWKKMIQDR
                     DAGWKDYINICKVGGTKSFLDIVSMGNLYSPFDDGCIESIIGDVKSWFDEINDSKL"
     regulatory      9919..10029
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            10133..10504
                     /locus_tag="PC466_001587"
     CDS             10133..10504
                     /locus_tag="PC466_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrdX family protein"
                     /protein_id="HDF2768975.1"
                     /translation="MIIITNNPKVKEEVQGREVLFKDTTYIGILEASRDLIHEGYELL
                     SHPLYGSVKPNETPYRTVILKKGNRLDINSLTLIEEAIITASKFQDNKKTPKWTENVQ
                     DDFRVIDYDIFYNTIQRMQYE"
     gene            10600..11547
                     /gene="trxB"
                     /locus_tag="PC466_001588"
     CDS             10600..11547
                     /gene="trxB"
                     /locus_tag="PC466_001588"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HDF2768976.1"
                     /translation="MENVYDLVIIGSGPAGLAAGLYGARAKLKTLILEKDKTGGQIVI
                     THEIANYPGSVPNATGPSLIARMVEQCKEFGAEMLRDNIVDTELDGDIKVLKGEKAEY
                     RAKAVIIGTGATPRKIGCPGEKELTGKGVSYCATCDADFFEDFEVFVVGGGDSALEEA
                     MYLTKFARKVTIVHRRQGFRCAKSVEEKAKANPKIEFLLDTVIEEIKGDGILESVVFK
                     NKVTGETHEYFADEEDGTMGVFVFVGLDAQTDLFKGKVDMDEKGYIITDEDMRTNIPG
                     VFAAGDCRSKTLRQVVTATNDGAIASIVAEKYIDEKFGN"
     gene            11632..11949
                     /locus_tag="PC466_001589"
     CDS             11632..11949
                     /locus_tag="PC466_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol reductase thioredoxin"
                     /protein_id="HDF2768977.1"
                     /translation="MLDLDKATFEEEVLNAEGFVFVDFWSEGCEPCKALMPDVHKLAE
                     TYGDKIKFCKMDTTKARRLAIKQKVLGLPTMAIYKDGEKVDEVTKDDATVPNIENMIK
                     KYL"
     gene            12218..13504
                     /locus_tag="PC466_001590"
     CDS             12218..13504
                     /locus_tag="PC466_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006439082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase component B
                     subunit"
                     /protein_id="HDF2768978.1"
                     /translation="MRLELGKIFIKDIQFGDVTEVKDGVLFINKQEMLQEIGGDEHIK
                     SIDIELARPGESVRITPVKDVIEPRVKVEGNGGIFPGIMSKVDTVGEGKTHALKGVAV
                     VTTGKIVGFQEGIIDMTGEGAKYTPFSKLNNVVVIAEPIDGLKQYAHEKAVRMIGFKA
                     AMYLGEVARNLTPDEVSVYETKPLLESIKEYPELPKVGYVYMLQTQGLLHDTYVYGVD
                     AKQIVPTLLYPTELMDGAIVSGNCVSACDKNPSYVHINNGVVEDLYARHGKDINFVGV
                     IITNENVYLADKERSSNWTSKLCKYLGLDAVIVSQEGFGNPDTDLIMNCKKIEMQGVK
                     TVIVTDEYAGRDGGSQSLADADVRADAVVTGGNANQVVVLPKLDKVIGHLEVVDVIAG
                     GSDGSLRADGTIEVEIQAITGATNETGFGHLTAKGY"
     gene            13616..14089
                     /locus_tag="PC466_001591"
     CDS             13616..14089
                     /locus_tag="PC466_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:13748..13750,aa:Sec)
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase complex
                     selenoprotein A"
                     /protein_id="HDF2768979.1"
                     /translation="MSLLSNKKVLIIGDRDGIPGPAIEECVKTVEGAEVVFSSTECFV
                     UTAAGAMDLENQNRVKDAADKFGAENVVILLGAAEAEAAGLAAETVTAGDPTFAGPLA
                     GVALGLSVYHVVEEPIKSLFDESVYEDQISMMEMVLEVEEIEEEMSGIREEFCKF"
     gene            14121..15431
                     /gene="grdB"
                     /locus_tag="PC466_001592"
     CDS             14121..15431
                     /gene="grdB"
                     /locus_tag="PC466_001592"
                     /EC_number="1.21.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:15168..15170,aa:Sec)
                     /transl_table=11
                     /product="glycine reductase complex selenoprotein B"
                     /protein_id="HDF2768980.1"
                     /translation="MGKLKAVHYINQFFAGIGGEEKADTKPHVAETLPPISLQLDKLL
                     GEDIEIVGTVVCGDSYFNENIDSASEEVLSMVKGFEPQLFIAGPAFNAGRYGVAAGTI
                     TKVVKDALNIPALTGMYVENPGADMFKKDVYVVETSDSAAGMRKALPKIAKLAVKLAN
                     GEEIGTPKDEGYIARGIRVNYFHEDRGSKRAVDMLVKKIKGEPFETEYPMPNFDRVDP
                     SKAVKDLSKCKIALVTSGGIVPKGNPDRIESSSASKYGTYSIAGVMDLTEETYETAHG
                     GYDPVYANLDADRVLPVDVLRDLEKEGVIGKLHETFYTTVGNGTSVANSKKYASEIGA
                     ALVADGVDAVILTSTUGTCTRCGATMVKEIEKTGLPVVHMCTVVPISLTVGANRIVPT
                     IAIPHPLGNPALDPTEEKALRRGLVEKALNALTTEVDGQTVFEK"
     gene            15688..17220
                     /locus_tag="PC466_001593"
     CDS             15688..17220
                     /locus_tag="PC466_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014520415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III family protein"
                     /protein_id="HDF2768981.1"
                     /translation="MTYPVLKGAGYVLIHTPDMIVQNGSTCTVERATNSDSEFLKEVS
                     NHIRSYEDVVNYMPNQVYIGNRRPEELRDLPMPWCEQKIEGTRNGKFGEIMPQDEFIA
                     LMQISDAFDLVKLSQEFIDEVKPKIENNYPEIAPFVGKLKGDDIEEGKELVATHIAEG
                     LYHDGKFVGYVKRAHDVDVNLNAHTMFENLVVKASGVLSAIQMLRHSKIDPAEIDYVI
                     ECSEEACGDINQRGGGNFAKSIAEIAGLQNATGSDTRGFCAAPTHALIQAAALVKAGI
                     HKNVMVVAGGASAKLGMNAKDHVKKGLPVLEDVVGGFAVLVSENDGVNPVIRTDLTGK
                     HTVGTGSSPQAVMTALITSGLDRANLKITDVDVYSVEMQNPDITKPAGAGDVPEANYK
                     MIGALAVKRGDLEKKELKDFVSNKGLPGWAPTQGHIPSGAPYIGFLIDDLTTGNRNRA
                     MIVGKGSLFLGRMTNLFDGVSFIAERNTGVTEETSGISKDEIKKIIAESMKKLALDML
                     EE"
     gene            17231..18376
                     /locus_tag="PC466_001594"
     CDS             17231..18376
                     /locus_tag="PC466_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine reductase"
                     /protein_id="HDF2768982.1"
                     /translation="MSKKVIADVFLEVANAIESGEFGKKVKIGVTTLGSEHGVENMVN
                     GAQLAKSNLFDIVLIGPKVETDLEVVEVNDEKEMHAKMEELLDSGYIDACVTMHYNFP
                     IGVSTVGRVITPAKGKEMILATTTGTSATNRIEAMVRNAIYGIATAKSMGNKCPKVGI
                     LNVDGARQVEKCLKELKDNGYDMEFADSIRADGGCVMRGNDLLVGAPDVMVTDTLSGN
                     IFMKVFSSYTTGGDYEAQGFGYGPGVGEDYDRKVLIVSRASGSPVVANALKYAYDVVK
                     GDISNVARNEFAKVKKAKFDDIISSLTKKEVKAEKVEVKMPDKEIVTRQIAGVDIMDL
                     EDAVSELWKNGIYAESGMGCTGPIVLVNEAKGDLAVETLVKAGYTAK"
     gene            18686..19765
                     /locus_tag="PC466_001595"
     CDS             18686..19765
                     /locus_tag="PC466_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HDF2768983.1"
                     /translation="MSRVKNVVGLLGTKGVDALYLTKKTNVNYISGFPDEEAYAVICK
                     DGNFLVTDSRYMELAEKVCKDFEIINWHNFDRSVAKAVKSVCDKVGIKKLGFERTNIV
                     FDKYEELKNLIEKDNGELIPTENIVETLRYVKDKDEIKNTRKACEIADKALEELIPHI
                     KAGVSEIELATKLEYFMKMNGAQNIGFETILISGAKTSLLHGKPSDKIIEKGDFVLID
                     YGAMYNGYISDTTRTFIVGGASEKQLEIYNLVKEAQNVGVENMKAGVHATIPDAEIRK
                     VVKKYEDYYYQGIGHGVGRDVHEEPFIGNYGDKIIEEGCIITMEPGIYFPGWGGVRIE
                     DTVLITKNGPERLTKFPKDLMILDK"
     gene            19878..20477
                     /locus_tag="PC466_001596"
     CDS             19878..20477
                     /locus_tag="PC466_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768984.1"
                     /translation="MYKKHKFIKNIKKAWYKIKLIDRCLIIVMAILMFQSIYNLFVNE
                     VNSQDTTTIDVVVRTTSAAIFGYFLSANFIKRPLRKYTNTDVSSNLFIDNNLPPKGQE
                     SSQNNIMNVKNTIGFTSEADNYEKKIPINNNEGFEEGETSELQIIIATVICIAALTVL
                     FVVRNFTTTTSASLGTISQMRDFVSGCVGFLLGCPSKPD"
     gene            complement(20664..21536)
                     /locus_tag="PC466_001597"
     CDS             complement(20664..21536)
                     /locus_tag="PC466_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDF2768985.1"
                     /translation="MNINYLYYFQTVCKYKNMTKAAESIHISQPSITLAIKELEKELG
                     FELFYRIGNKIELTPEGKIFLDKSKHFIKQFEDFQCDALDLGKKRKASLKIGIPTVLG
                     TFLLSKILPRFNVIYPDIELKIFEVPTFVGAKMIEESTLDFCIGIIDSDIYDDIDSKT
                     IYKTELYLVTNPKNELAKHPIISNYMLKNVPFVILSEGSYHYKIITKRLEKAKPNIIL
                     HSNQLSTIRYLLENDLASTILYKEIFQNTENLCSIPLERAITANIGVLWRRNQYISHS
                     MKLFIEYMASIHIN"
     gene            21953..23356
                     /locus_tag="PC466_001598"
     CDS             21953..23356
                     /locus_tag="PC466_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768986.1"
                     /translation="MKGSDLVKFELMDFLMNPFVLMFAAVITGILFGKIKFGKFNFGV
                     SGALFTGLFIGWLAYSLGNLIIAKGETAAGYKAATVMMGNGIISSDFFDFFLIIFVAA
                     VGLLAAKDMKAVLKKYGARFVILGVLITFIGGSMTYAMTLLSSDKGSSAYEVSGVYTG
                     ALTSSPGLAAALETAGKHAEDVSKEFEKASIKDKKEILKVVDPEGKLDVNTTTSLTQE
                     QIDKYIAYAEAGVGIGHAVAYPFGVLIVILGVNFLPKLFRMDLKEERRKYEKEMKEAR
                     DSVSGKTIPEVPFNIITFFLTCLAGYLVGGIHVFMGPLGYFTLGATGGSLIVSLVLGY
                     IGKIGVVNFRMEEKVLNILKQIGLVFFLAIVGLRYGGKVVDSIMTSGMHLALVAIAVG
                     VTAMMIGFLVGKYVFKLNWILLSGAVCGGMTSTPGLGAAVDALDSDDPAAGYGATYPF
                     ALLTKVILVIVLHKLPM"
     gene            23383..24927
                     /locus_tag="PC466_001599"
     CDS             23383..24927
                     /locus_tag="PC466_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA hydrolase/transferase family protein"
                     /protein_id="HDF2768987.1"
                     /translation="MNNEGAFEELSGRLRNKELCDLIMNADEAAKIIEDGMVIGVSGF
                     TPSGYPKAVPLAVSERAKSGEKIKLTVYSGASLGPEVDGAWSEAGIIERRLPYQTNSI
                     LRNNINKGVVDYIDMHLSHSTQFLNYGTIPKVDVAIVEALAITEEGNIIPTSGIGNSP
                     SFIKSADKVIVEINLAKPMEMEGMADIYITENPPNRKPIEINHPKDRIGTTYIPCGLD
                     KIAGVVITNMQDKTRPLGVVDEASKKISNNIIAFLREEVKAGRLSKNLLPLQSGVGSV
                     ANAVLYGLCESEFENLTCYTEVVQDSMLDLIRMGKVTMASTTSVSPSPEGLIKFEKDI
                     DFFKDKIILRPQEISNNPEIARRIGVIAMNTAIEVDIYGNVNSTHIMGSKMMNGIGGS
                     GDFARNGAITIFSTESIAKNGDISSIVPMVSHVDHTEHDVMVIVTEQGYADLRGLAPR
                     ERAIKIIENCAHPDYKEQLRDYLNRACKSGAKQTPHILDEALSWHSKFMSTGTMKKAE
                     TFKSAL"
     gene            24958..26349
                     /locus_tag="PC466_001600"
     CDS             24958..26349
                     /locus_tag="PC466_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase family protein"
                     /protein_id="HDF2768988.1"
                     /translation="MEKAVENFEDLSKEYINGYIERARKAQREFECYTQEQVDKIVKI
                     VGKVVYYNAEYLAKLAVEETGMGVYEDKVAKNKSKAKVIYNNLKDKKSVGIIDIDRET
                     GITKVAKPVGVVAAITPCTNPIVTPMSNAMFALKGRNAIIITPHHKAIGCSTKTVEMI
                     NEELEKIGAPENLIQILDQQSRENTRNLISSADVVIATGGMGMVKAAYSSGKPALGVG
                     AGNVQCIIDRDVDIKEAVPKIIAGRIFDNGIICSGEQSVIVAEEMFDKIMDEFKNNKG
                     FIVRDKVQKEAFRNAMFVNKSMNKDAVGQSVHTIAKIAGVEIPEDTKIIVIEADGPGE
                     EDIIAKEKMCPVISAYKYKSFEEGVAIAKANLNVEGKGHSVSIHSNTVKNIEYAGENI
                     EVSRFVINQCCATSAGGSFFNGLAPTNTLGCGSWGNNSISENLDYKHLINISRIAYYM
                     PENEVPTDEELWG"
     gene            26542..28038
                     /gene="abfD"
                     /locus_tag="PC466_001601"
     CDS             26542..28038
                     /gene="abfD"
                     /locus_tag="PC466_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxybutyryl-CoA
                     dehydratase/vinylacetyl-CoA-Delta-isomerase"
                     /protein_id="HDF2768989.1"
                     /translation="MALMTGAQYIESLRKLNTKVYMFGEEVKNWVDHPMIRPSINCVA
                     ATYDLAHDPEYADLMTVTSNITGEKINRFGHLHQSVDDLIKKVKMQRLCGQKTASCFQ
                     RCVGMDAFNAVYSTTFECDKAHGTNYHDNFVKYLTYIQENDLVVDGAMTDPKGDRSLS
                     PSAQPDPDMFLHIVERREDGIIVRGAKAHQTGSINSHEHLIMPTISMTEADKDYAVSF
                     AVPSDAEGVFMIYGRQSCDTRKLEEGADVDLGNKEFGGQEALVVFDNVFVPNDRIFLC
                     GEWDFSGMLVERFAGYHRQSYGGCKVGVGDVIIGAAALAADYNGANKASHIKDKLIEM
                     THLNESLYCCGIACSSEGHKTEAGNYQIDLLLANVCKQNVTRFPYEIVRLAEDIAGGL
                     MVTMPSEKDFKSDLKVGTSGMTIGEVCNKYFKASSVASTEERMRILRFLENICLGSSA
                     VGYRTESMHGAGSPQAQRIMISRQGNINQKKELAKKIAGIKKEEALNL"
     gene            28173..28448
                     /locus_tag="PC466_001602"
     CDS             28173..28448
                     /locus_tag="PC466_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2768990.1"
                     /translation="MTCGVRFCGGCNPRYERGKALTIIKEHFNGRVDFSIAQENVEYD
                     LLLIIGGCATLCASYQQYKVKNECVKMWDFSHIERVINVIESAICET"
     gene            28472..29779
                     /locus_tag="PC466_001603"
     CDS             28472..29779
                     /locus_tag="PC466_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA hydrolase/transferase family protein"
                     /protein_id="HDF2768991.1"
                     /translation="MSWQELYQSKLCSATEAVKQIKNGDTVVFAHCVGEPPALVEAMI
                     ENAEQYKDVEIKHMVSLGSGGYTAKGMEAHFRVNPMFVSGNVRKAIENGDGDFTPAFF
                     HEVPKLLREKRLKCDVVLAQVTPPDEHGYCSLGTSVDYTYEAIKTARTVIVQVNDQFP
                     RTYGEVVHVSEFDYIVEKSQPLFELQPAKIGEVEEAIGKNCASLIEDGSTLQLGIGGI
                     PDAVMLFLTDKKDLGIHSEMISDGTLALYEKGVINGKYKNFDKEKMTVTFLMGTKKLY
                     DFANNNPAVEVKPVDYVNHPAIIMKQHKMVSINSAIQVDLMGQVVAEAMGLRQFSGVG
                     GQVDFIRGVSMGEDGKAIIAMPSITTKKDGTVISKIVSIVDEGAPITTSRNDVDYIVT
                     EYGIAELKGKSLRERARNLINIAHPSVRESLAVEFEKRFKEKY"
     gene            29799..30917
                     /locus_tag="PC466_001604"
     CDS             29799..30917
                     /locus_tag="PC466_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxybutyrate dehydrogenase"
                     /protein_id="HDF2768992.1"
                     /translation="MEALRVVPKIFYFDTFKEFNEEFKIGKNDLVITNEFIYEPYMKP
                     LGIDTNLIFQEKFGTGEPSDEMIDSMTKEMKKYNFDRIIAFGGGTIVDICKILALDVP
                     EKSIDLFEGEVSPKKVKELVVVPTTCGTGSEVTNVAIAELKSKHTKKGLAVEETYADY
                     AVLIPETVKGLPYKFFVTSSVDALIHAIESYLSPKASPFTEMYSLQAIKMIMDGYKKI
                     VDKGEEERFNHLRDFVLASNYAGIAFGNAGCAAVHALSYSIGGAFHVAHGEANYQFFT
                     EVFKMYSRKKPNGKIIKCTKILADALECDPNCDVYGELEKFLNKLIAKKALREYGMVE
                     SQIDEFTDSTIANQQRLLANNYVELSREEIREIFANLY"
     gene            31204..32124
                     /locus_tag="PC466_001605"
     CDS             31204..32124
                     /locus_tag="PC466_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HDF2768993.1"
                     /translation="MYKSENFSKKSVLINSFLSKFLKIIGWGLVSLFTLSALVLSTIS
                     IIIGWAVILPIQVCAVFLLIGGVCIFKGKRLGDQISRYKKYCTIINNRNIIPVELIAE
                     NTSKSLNFIIKDVQKMIDKNYFINTYIDKRNNQIVLTNEDFIPPRYEDVAYEVKEEEK
                     TDESNEVDTIINKGMNYLTQIKEANKNIKSESMGDKIVQVEDVTSKIFDVVKHDPSKL
                     TQIQKFMDYYLPTTLKLLNSYHTLEEQGIDRENITTTMESIENTMNTIVVAFENQLDY
                     LFEDEAIDISTDITVLENMLVQEGLTSGKF"
     gene            32239..33396
                     /locus_tag="PC466_001606"
     CDS             32239..33396
                     /locus_tag="PC466_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HDF2768994.1"
                     /translation="MNNLDDIPVMPTLTLDPFGEESNTNDIDNSDLLMKKDEKDPEEE
                     KLSESERKMVKEFAEKIDITNTNMILQYGAGAQKKVASFSETALKSVKTRDLGEVGDM
                     LTNLVTDLKAFSADEKEQSGFLGIFKKANNKISNLKTKYDSAEVNVDKVSKELQKHQV
                     KILKDIAMLDKMYELNLAYSKELTMYIIAGKQKLKDMKEYEMPKLREKARLSGSTEDA
                     QSVNDMVSLCDRFEKKIHDLELTRMVSLQMAPQIRLVQNSNNLMAEKIQSTIVNTIPL
                     WKNQIVLALGISHLNQAMKAQREVSNMTNELLLKNAETLKMGTIETAKESERGIVDID
                     TIKKTNQSLISTIDEVVKIQHDGRIKRQEAEVELSKIENELKSKLLEFTVK"
     gene            complement(33481..34980)
                     /locus_tag="PC466_001607"
     CDS             complement(33481..34980)
                     /locus_tag="PC466_001607"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HDF2768995.1"
                     /translation="MAFYFDTPSHTFSEYLLVPGFSSTDCIPANVSLKTPVTKFKKGE
                     EADIYMNIPLTSAIMQSVSDDKMAIALAKEGGISFIYGSQTIENEAAMVARVKSHKAG
                     FVVSDSNIKPDNTLKDILDLKEKTGHSTVAVTEDGTSTGKLLGIVASRDYRISRMDLD
                     TKVSEFMTPMSSIVYANKDVTLKEANNIIWDHKLNSLPVLDDNGNLMYMVFRKDYSSH
                     KENPLELLDSSKRYVVGAGINTRDFAERVPALVEAGADVLCIDSSEGFSEWQKITLDF
                     IREKYGDTVKVGAGNVVDREGFLYLAEAGADFVKVGIGGGSICITREQKGIGRGQATS
                     IIEVAQARDEYFEKTGIYIPICSDGGIVYDHHITLALAMGADFIMLGRYFSRFDESPT
                     NKVNINGSYMKEYWGEGSARARNWQRYDLGGDKKLSFEEGVDSYVPYAGSLKDNVTLS
                     LSKVRSTMCNCGALSIPELQKNAKLTLVSSTSIVEGGAHDVMLKDNRNL"
     gene            35576..37000
                     /locus_tag="PC466_001608"
     CDS             35576..37000
                     /locus_tag="PC466_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICB"
                     /protein_id="HDF2768996.1"
                     /translation="MSSSNQSTIKTSIQRVGKFLSGMVMPNIGAFIAWGLITALFIPT
                     GWMPNEKLSTIGDPMIKYLLPLLIAYTGGKAIAGQRGGVIGAAAAMGVIVGADIPMFI
                     GAMIMGPFAGWVIKKFDKFVDGKIPTGFEMLVNNFSIGIIGMLLAILGFYAIGPAIVA
                     GTALIESGVQFIVSKSLLPLVSVFIEPGKVLFLNNAINHGILGPIGIAEAKEAGKSIM
                     FLLESNPGPGLGVLLAYWMFSRGSVKQSAPGAVIIHFFGGIHEIYFPYILMNPVLILA
                     TMAGGAAGILTFSILGAGLVAAPSPGSIFALMALAPKGGLLPVLAGVAVATVVSFLVA
                     APFVKRASANQSEEDSTSLEEAKAKMSDMKSASKNSEKNIEEKQLEVNEIKKIVFACD
                     AGMGSSAMGASRFKNRIKNLDLNIEITNSSVDNLPDDTQIVVTHNTLVERVAKNNSSV
                     EIVSINNFLNDPNLDALFKRLESK"
     gene            37035..39164
                     /locus_tag="PC466_001609"
     CDS             37035..39164
                     /locus_tag="PC466_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HDF2768997.1"
                     /translation="MKKKKITSRQKKIILMIVENSKKNIPITISEIAGTLELSSRTVL
                     RDMSGIEKWFDENDFNFVKKPGVGLILEENIENQNFIIELLEEEKIEKEYSKEERNLI
                     ILSKLLVSNEPVKSYYFAKILKVSEGVLNNDFALASKWLERFDIELVRKPGLGVYLKG
                     QEKNFREAYVNLIYDSFNEKEILDMVRNISENIQTDKAIEILSENRLLNLMDRCIIRK
                     VEATLTKKLSDLDVNLADSAYIGLVVHISLALQRIKNGENITMDKEFLKELSITEEFK
                     LAKEIVKGMETDFNMDIPVDEVGYITMHIRGAKQRSSSNHKALNLDDIEIMEITNKMI
                     DLAEDEFKISLKNDERLFKDLANHLGPSINRLNMGLEIRNPLLDEIKSKYSYAYDGVE
                     KISRIIKDKLNINSIPESEIGYIAMHFASAIEKNLMMNTNINIVVACPTGIGTSRFLS
                     TKIENKFPNLNILETISAINIDEEYLKEKDVDLIVSTVELNTSLNYICVGPFMSLDDE
                     QIIKEKIKSIAQNKLINLNAKNDTKSKNKVYEQITESMNIGKDILQFLEEIRFEKFES
                     KDLSELIEDSSKIFAKSSEDIISIKESLKERLKISIPYIEESKILLLHCMSERIDIMK
                     LSIIKLENRIVLDSNEEIDNVVFMLLPKNSPSYQRQIMSEISGSLIDNIIFTNKINKF
                     SIEEMTLEVKDIVFNFYTNRLKAFIDK"
     gene            39194..39616
                     /locus_tag="PC466_001610"
     CDS             39194..39616
                     /locus_tag="PC466_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2768998.1"
                     /translation="MSKVLNENNIFLGLDSVSKEEAITLAGRKLVENGYVKEEYIPAM
                     LEREKVMTTYMGMGVAIPHGVNEAKKEILSSGIVILQFPNGIDFDGEKAYLLIGIAGV
                     GDEHLEILSNIAVVLDDDLTERLKNSNDKQAFMEAFAN"
     gene            39635..40786
                     /locus_tag="PC466_001611"
     CDS             39635..40786
                     /locus_tag="PC466_001611"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HDF2768999.1"
                     /translation="MKKAIQFGAGNIGRGFIGSLLVKSGYHVVFADVNEEILNSINKD
                     KKYTIHIRDVECIDEVIDNISAVSSIKEEIIDEIVQAEIITTAVGPLVLTKIASTIAK
                     GIKARKEKGLTSNLNIIACENAIYASSSLKEEVLKYLNKEEVEYLEMYVGFPNCSVDR
                     IVPPGKNENPLDVTVENFYEWNVEKQGFKGEIPTIVGMNLADNLMAYIERKLFTLNTG
                     HAITAYIGYLKGYKTIEESIKDKFICDIVKSAMVESGEGLIKKYNFDSEVHYKYIDKI
                     LNRFKNPYLNDDVLRVGREPLRKLSDKDRLIKPLMTAKSYGLSVDNLILGIGAALHYN
                     NSEDTQSVELQELIKSIGVKKAVAKIANISNDEEILNNIEKSYIFMKNL"
     regulatory      40892..40993
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            41176..41748
                     /locus_tag="PC466_001612"
     CDS             41176..41748
                     /locus_tag="PC466_001612"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HDF2769000.1"
                     /translation="MKALQEKILREGSVSGNDILKVDSFLNHQIDVAFLNEIGREFKE
                     RFKGEKVDKIFTIEASGIAIASIVSQYFDNAPVVFAKKSESKNLDKDVYETNVYSFTK
                     AREYSVKVSKKYINKGENILIVDDFLANGRAALGLKDLIEQAEANLVGVGIVIEKGFQ
                     AGGALLKANDVRLESLAVVESIDNGTVKFR"
     gene            41812..42462
                     /gene="fsa"
                     /locus_tag="PC466_001613"
     CDS             41812..42462
                     /gene="fsa"
                     /locus_tag="PC466_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HDF2769001.1"
                     /translation="MRFFIDTANIEEIKEANDLGVICGVTTNPSLIAKEGRDFIEVVK
                     EISEIVDGPISAEVISLEHKGMIEEAEKLSKIHKNIVIKIPMTAEGLKAVKVLSSKGI
                     KTNVTLIFSAGQALLAARAGATYVSPFVGRLDDISQNGLDLIEEIVDIFSVNSIEAQI
                     IVASVRNPIHVLQAARMGADIATVPLKVINQMIKHPLTDKGIDSFMKDWEGAFLKL"
     gene            42614..45538
                     /locus_tag="PC466_001614"
     CDS             42614..45538
                     /locus_tag="PC466_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2769002.1"
                     /translation="MDKILREIQREDKKNPYTDQELAEMLNVARSEVISVRKKNNILD
                     SRERRKKILIKDISKIVSENPQMSERKITEILIENGYNISRSAVSKLLKEENLNQSKI
                     GIKDKDPASSGKYVKVSKVVEEDGFEELIGIKGSLKEKVNLAKSAIMYPPNGLHTIIY
                     GETGVGKSELATCMYKYAIKNNIKEENSPFIVFNCADYAENPNLLIAQLFGVVKGAYT
                     GADANREGLVEQANNGILFLDEIHRLPAAGQEILFSLIDRGEFRRLGESSSNRKANVL
                     IISATTENPDSNLLQTFRRRIPMVINLPNMSERPKSERYEIIIKFFEREAKRVNKNFI
                     ITKEVMCALMNYKCTGNIGQLKSDIQVTCARAFSKSIFSSDKVIIDLDSLRDYIKSGY
                     YDCNCKNEKYSEFSVEDIYIDISELVSGKNRILSDNEISEIYNYAEKELKVLESKCFS
                     EEELKNAFIEKLDKKFNAIKNNKNLSDRRSRIDWGGQLKESTLEIMDKVIVFIKEQFK
                     HVNQGLYLALAIHIEHAIGRIKDGKTIINPSLDKIKASMPMEYELSRYIMGIVEDLTQ
                     VTFPEDELGYLAYYINKFCYNEESIKDKVKVVIVTHGKVGIEMSKVVNHILGIECTLG
                     IEIALTDSPSEGIEHVLEELQKIEARKGILVLIDMGSLVILGDEVEKRLGIRCKTVNR
                     VDTLLAMEAGKLATIEGKSLDGIIADLKKNKNYAMINTNKFSYRKNEYGKKNVIITLC
                     LSGVGTALNLKEHIEKQIKEYGTLIEVKPVAFLNNNLEEELNDIEAEYNIIAICGTID
                     IDYKNVPFISYNEVLGKNGINKVLEHLNSKQPALNIENQLNNLIHEDLILYNFEGISK
                     EYIIDTLVSKLEEGGYVDSKYILSVYKREAMGSVVMASKVAVPHGLPENVIKPAIAIA
                     RLNKPIVWDNKFMVDLVVLLALKENNKKEIRSLFSKINDQHTLEVLLNTEDKNEIKEL
                     LS"
BASE COUNT        18016 a         5008 c         8495 g        14231 t
ORIGIN      
        1 atatagctaa tatctatttt acagataaat aagaataaac ttataatata attgtatctg
       61 taaaattttg taaaatataa aaagtatagg gggaataaaa atgaaagtag cttatatttt
      121 tagtagtact aatacacata aaattctaga caaaatgata ataccacaac ttgaacaagg
      181 aactcatgga gtagacgttc tagggatgtt tttctttatg gataatacct tatttttatc
      241 taaaggtaat ccagtaggcg agagactaag taaattacat gaaaaaactg atatgataat
      301 aatggcttgt gaccaatgtg ctatagaaag aggtatagag aataatttgg ttgatggagc
      361 tacaattgga tgtttcccaa acctatatgc ttgtttaggc agtgcaggtg tggaccaagt
      421 tataacgtta taaattagta taggatacaa tccatagaaa aatttatttt ctgtggatta
      481 ttttaagtaa aagataaatt gtttaaagta ggggatgaac aaatgtctaa aattttagtt
      541 gaatttataa acacttgacc atcttgtgat gaacatggag tgtttataaa aaaaatgtca
      601 gaaaagtatg ctgataaatt ggaaataaaa ttatatcaag cagggaaaga tttttcgtat
      661 ataaaaaaat atgggattat aacaaaagga actttaataa taaatcagaa aaagaaatat
      721 gatagattaa ataaagatac aattgaaagg gcaatagtag aagctataaa caataattaa
      781 aagtttaaaa attaggagta tcaaaaatga atatattaga aattgtttta aatggagtta
      841 aagatactat agtagcttct atagttacac tgaatggagc atcaggatgg cttatgataa
      901 gttttatatt ggcaggtgta cttcacaatg ttttaactcc aagaaggttt caaaaacaac
      961 ttggaaataa gaaattttct tctttaatta aaagtactat ctcaggaatg tttttaccaa
     1021 tatgtagttg tggagtaata ccacttggaa taagtatgta ttattcagga gcatatttag
     1081 gaccagtact tgcttttatg acatcaactc caataataaa tccaatagct gtagttcttt
     1141 gtctaggtct tttaggtcct aaagttacaa tcatttatct aatagctggt tttttagtac
     1201 catttttagt aggattttta ggaaattgtt ttggaaaaga agaattatca ctttataatg
     1261 attcagagga agaagtaata gaattagaag aagaaaaaag aagttttatg gaaaatatga
     1321 ttgatggtct taaatggtct tttggtgaat tagcccttac tattagtaaa tatgtagtaa
     1381 tgggtatggt ttttgcagga tttataacaa ctatttttcc aaatagtata attcaaaaat
     1441 atttaggaaa tccaggtttg ctatctcttg gaagtatagc aatacttgca tgtgttatgt
     1501 atgtatgtgc tgtaggacat ataccgttta tagcagccct tgttgcaagt ggagcatctc
     1561 ctggtatagc gataacattt ctaatagctg gagcagctac aaatctacca gaacttataa
     1621 gcatgtttaa acttattgga aaaagaactg ttattatata ttctgtaact ttgacactgt
     1681 cctcaataat aattggatat ataacaaatt tacttttagt gaataataat tcagtaaatt
     1741 tagatgcaac aaattcttca atacagttgg caaataaact aatgttaaat atacctgata
     1801 gttttgagta tgtatgtact attttaatta ttttatttgc atttaaatca acaataccaa
     1861 agatgaaaga ggtcatagga aatcatgctt aaaaagatag ttataatatc ctgtatagta
     1921 gttgtgttaa tcattttatc aaaaatagtt gatgataaca tcaaagaaga tgcttctatt
     1981 ccaaatgtga ataaagaaac attagaatat tttagaaaaa attataaaga agacataata
     2041 acttgtgctg aagaagattt aaataatgat gggaaaaaag atttagtagt tatatataaa
     2101 aaaagcaata attcaaatga aatggtagtc gtagtttctg ataaaaatag ccactatata
     2161 acaaagccaa taccagcacc tatagagaat caaactataa cctttaaaaa tattgatgat
     2221 aaagcaccaa tagaagtaat agtatcaggg tctaaaaatg gtaatgtagg atatgctatt
     2281 tacagagtag agggtaaaaa atttgttgat ttatttggcg aagatatgga caaatgttgc
     2341 taaaaataaa aataatacat aaaggtggga aatttatatg aaattatcta agaagattca
     2401 agcactaatc ttatttggtg taatgggtac atctatatta acaggatgta gtagtaaacc
     2461 aaaagaaaaa gaagaagcaa aagctggaaa agatgattat acaataacag taggttatta
     2521 taattgtgac catatgactg cgggaccagt agcagaatcg gcaggaatat ataaagattt
     2581 aggtcttaat gtaaaaactg ttggaaatgg taaagttcct gaagctatgg cagcaggaaa
     2641 aatggatgca ggttacatag gaactaaggg gttagttgga gcaataccta agggttcacc
     2701 aataacaata gcagctaaca accatactgg tggttctgaa tatttaatag tttcaaaaga
     2761 tataaaagaa cctaaagatt taataggtaa aaaaattgca acagatatga gtgatttctt
     2821 atggacaagt gattatggtc cagaaacagg tctaccaact gacccatcaa aatatgaagt
     2881 tgtaaatatg gattcagaca aagataaata tttagctctt aaaactggga aaattcaagc
     2941 ttttacatct tgtgaccctt ggggttctgt agctgaaaat gacggtgcag gaaaaataat
     3001 agcatctact caatataaag aaaaagctaa tggcaaagaa tataactgtt gttcattctc
     3061 attaaacaaa aactttataa aagaacatcc agatttagca aaaaaattgg ttctagcaca
     3121 tacaaaagca atagaatata tatatacaaa tccagctgaa gcagctaaaa tatttgcaaa
     3181 atattataat gtagaagaag aagttgcact tagaactatc tataagaaga ctgttggaga
     3241 aggtagaact cttacttgga aagttacagg tgaagaatat aaaaataatt tacaaatgta
     3301 taaagattta aaggctttag atgatatacc taaatatgaa gatacgattg atacaagctt
     3361 attggactct tgtggagctg atgattttga caaatttata aaagaaaaag ttaacccaga
     3421 gtttcctgaa ggtatgagtt atgaagactg gaaagcaaag gtattataaa taaatggaga
     3481 atataaaaaa tataataata ctttttatca ttattttggg aagtatattt ataatatttt
     3541 ttaattttga agataaagaa gaaataaaag gaaaattaag aataggggta tctgatgata
     3601 cctctggttt tgtaataaat tatatggtaa atagagacta ctttgaaaat ataaaagtaa
     3661 gtgatataat ggatattttt acaattaatg attgctgagc aagtacaatg cagtgggctc
     3721 tgagttcaga ggaaatagat atagcaatca tatgtaaaga tgctgcaaaa caatatgtaa
     3781 atgtaaatag tggatttgaa attgttggta ctgtagttca aaattctgat atatttctat
     3841 taagtgataa taatcctgaa aagataggag tcattcaaaa tagagattac cagtcagaat
     3901 tggttaaaaa atactacaag aatgtggaag tagctccatt attagggact gcactagcat
     3961 atggattaga aagtaattta gtagatggtg ttgtaataga ttgcataaag tcaattgggt
     4021 tagagggtaa aagaaaatct acaactaaat taggagatta tgatacctat gtattagttg
     4081 taagtaaaga gtttaaaaaa agtaaagcat atagtgattt tataacactt tacaataaaa
     4141 gtgttgatgc tttaaagaat aaagctacat ttaagaaagc attaaaagag tacaggaata
     4201 taagaaatat agatatggag gaaataagca attggaaatt aaaatttcta aagataaaag
     4261 cgatagatta actaagaaaa aaactgatgg tagtatggat attttatata aaataatact
     4321 attagttatt atatttttag tctggcattt tgcagcaaaa gatataggga gttctttgtt
     4381 acttccaatg ccagtagatg taataaaagg tttctttttc tgtgtgacag atgcagagac
     4441 agtcactaat ctttttataa cattgcagag agtacttaaa ggttttatgt atgcattatt
     4501 gtttgggctt ccaataggat ttattatggg attttctaaa acttttgaaa gggttttatc
     4561 tccagtagta gattctgtaa ggcaagttcc aataatggca tgggttcctc ttactatagt
     4621 atggtttggt ataggagatg gtccaacaat atttttaata gctttttcag gggttttccc
     4681 tataatttta aatactattc aaggagtaag agcaatatca aaggattatt ataatgcagc
     4741 tagaagtatg ggagcatcgc caattgtgat atttacaaat gtaattgttc ccgcatctct
     4801 tccagatata ctaactggtt caaggattgc tataagtaca ggatggatgt ctgttatctg
     4861 agccgagttt atagctacga gtgccggtct cggttactca atggtacaag ctcaaacatt
     4921 aatgcataca gatgtattaa ttgggcttat gatatttgca gctttaatag gatttataat
     4981 agatagggta ttaaagttta taaataaaat cctttgtaga tggaggtttg cagattaatg
     5041 aagttaagtg taagagatat aaataagaca tttgtaaata atagagtaca tacaaaggtt
     5101 ttagaagata taagtatgga tatagatgat ggacaatttg tctgtctttt aggaccatca
     5161 ggttgtggaa aaacaacttt acttactata ataggtgggt ttcaaaaatc agaacgtgga
     5221 gatgttttta taaatgataa aagagttaaa aaaccgggca tagatagagc ttttatattt
     5281 caaaattatg ctttatttcc ttggaaaact ataagaggta atgttctatt tcctatgaaa
     5341 cagcagaaaa taccaaaaga aaaaagagaa gaaatgctag aagaactttt ggttatgtca
     5401 gacttgaaag gaaaagaaaa actgtttccg catcaattat ctggaggaat gaaacaaaga
     5461 gtggccatga taagagcttt agcatgtaat ccagaggtat tactaatgga tgaaccatta
     5521 ggagctgtag attttcaaat gagacaaaat ttacaggaag agctagaacg aatatggata
     5581 aagaagaaaa taactgcatt aatggtaact catgatgttg atgaagctgt atatatgagt
     5641 gatagagtta tagtaatgtc gagagataaa ggaagaatta ttgatgatat aaatatagat
     5701 attccaagac ctagaattag aggaagccaa aaatatgaag agtacaaaaa caaattaact
     5761 gatactttat caaagtgtta tgaagtttaa agaggagtag acatgagtca aatagaaaaa
     5821 tacaatagtt tggataatac acaacagaaa ataagaatct ctattatgga tatgataata
     5881 gataaaggtt ctagtgttac acttcaagaa gtgactgaat atgtaagtaa aaagttgaat
     5941 atagaaaaag aatatataga aaggacacta caatatttta tttatgaaaa tataatggtt
     6001 gttgatggga atagtataaa ttttatatat cctgtatcag cattgcaaac aaatcataaa
     6061 gtaactttga gagataatag aagtttcagc gcaatgtgtg ctatagatgc tataggaacc
     6121 tcttgcacat tcaaccaaga tataaaaata aactctattt gtagtgctac aggtaaggaa
     6181 atagaagtaa ttataaaaaa tgaaaagatt gagtatgtga ataatccaaa cttaagagtg
     6241 cttcatataa atcttgataa gcatctaaat tgggctgcta gttgctgaaa tataatgaat
     6301 ttcttctgga cgaagagtga ttttgatgct tggacaaacg aagcgggatt atctgatgat
     6361 gaagatatat attgtttaga tattaatgag gcaatagtag aatcatataa aatatttaaa
     6421 ctcaaacaaa aggtactatc atagatatac atatatgaaa aactaaaaat gacctttaga
     6481 taaaaatgat aggtaatatc catactatat aaattagtat agagtaggga tgtgaaaagt
     6541 atttaaatct aaaggtatat ttttagtttt tttagatgat tagatagcct tattaagtat
     6601 atatttattt ataacctttg caactccatt ttcattatta gtatcagtaa cataatctgc
     6661 aatttccttt atactattac gtgcattccc catagccaca ccaagacctg catactttat
     6721 catatgttgg tcattttctt catcgccaac agcaatagca ttttctatag gtatatttag
     6781 attcgtacat aatgttttaa gagcagttcc tttattagta gttttaccta aaaattctag
     6841 ataaaaagga gcagacctta ctatagtata tttattgaat aaatttttag gtagttgctg
     6901 tatgatttct tccaatcttt ctggttcatc aactatcata attttacaga ttttaataga
     6961 ttcatcaatt ttatcttttt gtatatattt gacttctata ttatttaatt tcgcttcatg
     7021 aagtgtatat tttccaggtg cttcatttgg tgtaattaaa tttgtcattg tatttatgtg
     7081 tattttagtc ttatattttt tacaaacgtt attatatata aaatcaaaat catctaaagt
     7141 catttctaca tcatgtatga ttttctcact tttaacttct tgaataattg ctccattaaa
     7201 gcatataaca taatcacctt catctgttaa atttagttga tttagaagtt cttttacacc
     7261 aggaagaggt ctgcctgttg ttataactac ttttgcccca gccctttttg cctcctgaat
     7321 ggactcaaag acttcaggag taatcctttt ttgtgtattt aatattgttc catcaatgtc
     7381 tagtgcgatt aatttgtaca tatcaacctc caataaatta tatactcaaa tttcctgtga
     7441 aaacgttgac acagctagtg ttgaacaaag tttcagtggg aaatatggtt tgttttgtat
     7501 actattatat caagagataa gtaatttaga aagtttaata atattaattt ttgataaaaa
     7561 tattacttat gtgagatgag aatgtaaaaa ctttgtaatc aataattcca aaattcttaa
     7621 ttacaaataa tggtatcgtt tgcattgtta atataaataa atgtatatta tatagttaga
     7681 agtttgaata aatagactga tggtaatttg ttatattagt tagttttgtg ttataaaata
     7741 ttgtaattcc attaatcata tgttattatt caacatgatt ataatataaa gaatatttaa
     7801 tatatataat aatttataaa aaagtattac atagtacatg taaatctata tttataaata
     7861 caataaagta aagttgtaaa ggagtgcttt aaatgaagtt ttcagagttt aagtatgaaa
     7921 gacccaatta taatagtatg aaaaaagagt ttttgagttg tgtagaagat ataaataatt
     7981 ctcgtaatta taaagagcaa caaaaaaata tacataagat taatttatta agaaataaaa
     8041 tagaaacgtt gtcaaatata gcttcgataa gatatagtac agacacattt aataaattct
     8101 acaaagaaga aaaaaattat tgggatgaat atatgccttt gtatgaagaa ttaaattcac
     8161 atttttataa tgctattgta aattcaaaat ttaaatatga tttgataaaa gagtttggag
     8221 aacaattttt cacaatagta gagtattctt taaaaagttt ttctaaagaa ataataagtg
     8281 aattgcagga agaaaataaa ttgtgttcag agtatactag acttttagct tcagctgaga
     8341 taatgtttga tgggaatata agaaatttat ctggtatggg gaaattcatg tattctaaga
     8401 atagaaaaac aagagaatta gcaaacaaag catattataa tttctttgaa gaaaatgaaa
     8461 ctaaatttga tgacatattt gataaattgg ttaaacttag agataagata tctaaaaaac
     8521 taggttttga agattttgta gagcttgggt acgttagaat gatgagaagt gactacagag
     8581 aagatatgat aaaaaatgtt agaaaacaag tattaaaata tgttgttcca atggccaatg
     8641 agctttatga aaaacaagct aaaagaattg gtctagaata tttaagttac atagatgaag
     8701 gcgtggaatt tttaacagga aatgcaagtt taaagggaga ttcaagatac ataattcaaa
     8761 atggtaaaag gatgtattct gaactgtcaa aagaaacaaa tgaatttttt gattttatgt
     8821 tagaaaatga acttatggat ttagaaacga aaaaaggaaa aggagctgga gggtattgta
     8881 cttatatacc agattataag tcaccattca ttttttctaa ttttaatcaa actgctgatg
     8941 atatagatgt gttaacacat gaggcaggac atgcatttca gttgtatatg tctagatgga
     9001 ttgatatgcc agaaattaat tttccaacgc ttgatagttg tgaaatccat tcaatgagta
     9061 tggaatttat aacatggccg tggatggatt tattttttaa agaagataca gataagtaca
     9121 aattcactca cttatcatct tcaattaaat ttatacctta tggagtaatt gttgatgaat
     9181 ttcaacacta tatttacaaa aatcctaatg tagataagtc aaaacgaaaa gaaatctgga
     9241 gatttttaga gaaaaaatac ttacctcata gaaaatatgg tgataattct tttttagaga
     9301 gaggttgttg gtggtttaaa caaggacata tatttaaaaa tccgttttat tatatagatt
     9361 atgtattagc tcaaatttgt gcgttacaat tttggaaaaa aatgattcaa gatagagatg
     9421 caggatggaa agattatata aatatctgta aagttggagg aacaaaatca tttttagata
     9481 ttgtgagtat gggaaatttg tattctccat ttgatgatgg ctgtattgag tctattatag
     9541 gtgatgttaa atcttggttt gatgaaataa atgacagcaa attataaaaa attatgagaa
     9601 ttttattgta taaaagtgaa aaattaaaaa atatataaaa agtgattatt tgttgtgaaa
     9661 atagtcttgt ttttaactaa attgataaaa taaactaaaa aagatttgta cttaaaaaaa
     9721 aaagaaaata caagaaatat gcaatatcaa catttggaaa aaaaagtaaa aatgtataca
     9781 aaatacatat aaaaaaacta ttgcaaattt tatagaatgt ttatatactt aagtcaacag
     9841 agatagaaaa aagctattta tagaaaacaa aggataaatt gcttaatttt aaattttctg
     9901 aaaaaaataa taatccggat gaagagtatg ggagactgct ttataaaaag cgaccgaagg
     9961 gacaagttta atcttactta cccaaaagat tagatgaaat tctcaggtaa aggtgactgt
    10021 acttggacgg ggctctgaaa atgattttaa cagggaagac aaattgggag atttgttttt
    10081 cctgtttttt atttatcaag taataaataa aagtttgaaa gagagtaaaa aaatgataat
    10141 aattacgaat aatccaaaag taaaagaaga agttcaaggc agagaagttt tgtttaaaga
    10201 cacaacttat attggaatct tagaagcaag tagagatttg atacatgaag gttatgaact
    10261 tttatctcat ccactctatg ggagtgtaaa accaaatgaa acaccttaca ggactgttat
    10321 actaaagaaa ggaaatcgtt tggatataaa ctctttaacc ttaattgaag aagcaatcat
    10381 cactgcaagt aaatttcagg ataataaaaa gactccaaaa tggacagaaa atgtccaaga
    10441 cgattttaga gtaattgatt atgatatatt ttataataca atacaaagaa tgcagtatga
    10501 ataaaaaaat ttgttaaaaa gttattgaaa cagcctaaat attaaatcta atttaatatt
    10561 aaataaaatg agaaatttaa ttggggagga taagtcaaaa tggaaaatgt gtatgactta
    10621 gtaataattg gttcaggacc agctgggctt gcagcaggtc tttatggagc aagagcaaag
    10681 ttaaaaactc taatcctaga aaaagacaag actggtggac aaattgtaat aacacatgaa
    10741 attgcaaatt atccagggtc agttccaaat gcaacaggac caagtttaat agctagaatg
    10801 gttgaacagt gtaaagagtt tggagcagaa atgctaagag ataacattgt tgatactgag
    10861 ctagatggag atataaaagt tttaaaaggg gaaaaggcag aatatagagc aaaagcagta
    10921 ataataggaa caggagcaac accaagaaag attggttgtc ctggagaaaa agaacttact
    10981 ggtaaagggg tttcatattg tgcaacttgt gatgcagatt tctttgaaga ttttgaagta
    11041 tttgttgtag gtggaggaga cagtgcatta gaagaagcaa tgtatttaac taaatttgct
    11101 agaaaagtaa caattgtaca tagaagacaa ggatttagat gtgctaagag tgttgaagaa
    11161 aaagcaaaag ctaatccaaa gatagagttt ttattagata cagtaattga agaaatcaaa
    11221 ggtgatggaa tattagaatc agttgtattt aaaaataaag ttactggaga aactcatgaa
    11281 tactttgcag atgaagaaga tggaacaatg ggagtatttg tgttcgttgg attagatgct
    11341 caaactgatt tattcaaagg taaagttgat atggatgaaa aaggttacat aataactgat
    11401 gaagatatga gaactaacat accaggcgta tttgcagcag gagattgtag atctaagact
    11461 ctaagacagg ttgtaactgc aactaatgat ggcgcaattg catctatagt agctgagaaa
    11521 tacattgatg aaaaatttgg gaactagaat ctgtaaatta agaaatagtg tctgtaaatt
    11581 taatgaataa tatttaaaat taaaataaaa atttcaaggg ggaataagaa aatgttagat
    11641 ttagataagg ctacatttga agaagaagtt ttaaatgcag aaggttttgt atttgttgat
    11701 ttttggagtg aaggttgtga gccttgtaaa gctttaatgc cagatgttca taaattagct
    11761 gagacttatg gggataaaat aaaattctgt aagatggata caacaaaagc tagaagatta
    11821 gctataaaac aaaaagtatt aggtcttcca actatggcta tatacaaaga tggagaaaaa
    11881 gtagacgaag ttactaagga tgatgctaca gttcctaata tagaaaacat gattaaaaaa
    11941 tatctttaat atgttgataa agtattaaca ttaaaagaaa aaatctattt ttatctgaag
    12001 ataagaagaa aaaggttttt atgtccaact ttgttaaaaa aataatttta aataaaataa
    12061 tttttttaca ataaatattt tttagtaata aaataaagat ttaaggcata aaaacacaat
    12121 aatatatctt taaaaaaata agataaattg taaaatgata taattttgag aaaaactcaa
    12181 atgcatatac acaaattaaa taacaggagg tgcaagtatg cgtcttgaat tagggaaaat
    12241 ctttataaaa gatattcaat ttggtgatgt aacagaagta aaagatggag tattattcat
    12301 caataagcaa gagatgctac aagaaattgg tggagatgag catattaaat ctatagatat
    12361 agaattagct cgtccaggtg aaagcgtaag aataacacct gtaaaagatg ttattgagcc
    12421 aagagtaaaa gttgaaggta atgggggaat cttccctggt atcatgtcta aagttgatac
    12481 tgtaggagaa ggaaaaactc atgctttaaa aggtgtagct gttgtaacta ctggaaaaat
    12541 agtaggtttc caagaaggta taatagacat gactggagaa ggagctaagt atactccatt
    12601 ttctaaatta aataatgtag tagtaatagc tgaacctatt gatggtttaa aacaatacgc
    12661 tcatgaaaaa gctgttagaa tgataggatt caaagcagca atgtacttag gagaagtagc
    12721 aagaaatctt actccagatg aagtttcagt atatgaaact aaacctcttc ttgaatcaat
    12781 aaaagaatat ccagagcttc caaaagtagg atatgtttac atgcttcaga ctcaaggttt
    12841 attacatgat acttatgtat atggagtaga tgcaaaacaa atagtaccaa ctttattata
    12901 tccaacagaa ttaatggacg gagcaattgt aagtggtaac tgtgtttctg catgtgacaa
    12961 aaacccaagt tatgttcata taaacaatgg ggttgttgaa gacttatatg cacgacatgg
    13021 taaagatata aactttgtag gtgtaattat aactaatgaa aatgtttacc tagcagataa
    13081 agaaagatct tcaaactgga cttctaaatt atgtaaatat ttaggattag atgcagttat
    13141 agtttcacaa gaaggttttg gaaatcctga tactgacctt ataatgaact gtaagaagat
    13201 agaaatgcaa ggtgttaaaa cagttatagt tacagatgaa tatgctggac gtgatggagg
    13261 ttctcaatca cttgcagatg cagatgtaag agctgatgct gttgtaacag gtggaaatgc
    13321 caaccaagtt gtagttcttc ctaagttaga taaagttatt ggacatttag aagtagtaga
    13381 tgtaatagct ggtggttctg atggaagttt aagagctgat ggaactattg aagttgaaat
    13441 ccaagctata acaggtgcaa ctaatgaaac aggatttggt catttaactg ctaaaggata
    13501 ttaagaagta ttttattaaa cgattgagta atgttaataa aacatattat agataattat
    13561 aataagtgtt atagatatat aaaaatatat tagaaatata ataaggagga ttattatgag
    13621 tttacttagt aataaaaagg ttcttataat aggtgaccgt gatggtatac caggacctgc
    13681 gatagaagaa tgtgtaaaaa cagtagaagg agcagaggtt gttttctcat ctacagaatg
    13741 ctttgtctga acagctgctg gggctatgga cttagaaaat caaaacagag ttaaagatgc
    13801 tgctgataaa ttcggagctg aaaatgttgt gattttacta ggtgctgctg aagccgaagc
    13861 tgcaggtctt gcagccgaaa cagtaactgc tggagatcca actttcgctg gaccacttgc
    13921 tggagttgcc ttaggattaa gtgtttacca cgttgttgag gaaccaataa aatcattatt
    13981 tgatgaaagt gtatatgaag accaaataag tatgatggaa atggttttag aagttgaaga
    14041 aatagaagaa gaaatgtctg gtataagaga agaattttgt aaattttaat gcctaaaagc
    14101 aaaaggggtg aaactaagag atgggaaaac taaaagcagt acattatatt aatcagttct
    14161 ttgctggtat aggtggagaa gaaaaagctg atactaagcc acatgtggca gaaactttac
    14221 ctccaataag tttacaactt gataaattat taggtgaaga tattgaaata gttggaacag
    14281 tagtttgtgg agatagctat ttcaatgaaa atattgatag tgcaagtgaa gaagttttat
    14341 caatggtaaa aggttttgaa ccacaacttt tcatagctgg tcctgcattt aatgctggta
    14401 gatatggggt tgctgctgga acaataacta aagttgtaaa agatgctttg aatataccag
    14461 ctttaacagg tatgtatgtt gaaaatccag gagcagatat gttcaaaaag gatgtttatg
    14521 tagtagaaac ttctgattct gcagcaggta tgagaaaggc acttcctaag atagctaaac
    14581 ttgcagtaaa acttgctaat ggagaagaaa ttggaactcc taaagatgaa ggatacatag
    14641 ctagaggaat aagagttaac tacttccatg aagacagagg ttctaagaga gctgttgaca
    14701 tgttagttaa gaaaataaaa ggtgaaccat ttgaaactga atacccaatg ccaaactttg
    14761 atagagttga cccaagtaaa gctgtaaaag atttatcaaa atgtaaaata gctttagtta
    14821 cttctggtgg tatagttcca aaaggaaatc cagatagaat agagtcttct tcagcttcta
    14881 aatatggaac ttattctata gcaggagtta tggatttaac agaagagact tatgaaactg
    14941 cacatggtgg atatgaccca gtgtatgcaa atttagatgc agatagagta ttacctgttg
    15001 atgttcttag agatttagaa aaagaaggtg taattggaaa attacatgag actttctata
    15061 caactgtagg taatggtaca tctgttgcaa actctaaaaa atatgcttct gaaattggag
    15121 cagcattagt ggctgatggt gtagatgcag taatattaac ttctacatga ggtacttgta
    15181 ctcgttgcgg tgcaacgatg gtaaaagaaa tagaaaaaac tggacttcca gtagttcata
    15241 tgtgtacagt agtacctatt tcattaacag taggggctaa tagaatagtt ccaactatag
    15301 caatacctca tccacttgga aatccagcgc ttgaccctac agaagaaaaa gccctaagaa
    15361 gaggccttgt agaaaaagca ttaaatgctt taactacaga agtagatggt caaacagtat
    15421 ttgaaaaata aaaataacac acacatatat tatatagata aaaatataaa cacacactaa
    15481 aaataaaaaa taactataca caaaaaaaat aatatagatt tcatgaatgg ataaattgga
    15541 gttattcatt catgaaatct taaaaaatgc caaaatacat aaacaataat agaatcaaat
    15601 atacaataaa atacaatgat tagagctttt aataagttta ataagattaa aaaataagtg
    15661 ttcataaaat ttatggaggt gcacaaaatg acttatccag ttttaaaagg ggcaggctat
    15721 gtacttattc atactccaga tatgatagtg caaaatggaa gtacttgtac agttgaaaga
    15781 gcaacaaatt cagattcaga atttttaaaa gaagtaagta atcatataag aagttatgaa
    15841 gatgtagtta actacatgcc aaatcaagtt tatataggaa atagaagacc agaagaatta
    15901 agagatttac caatgccatg gtgtgaacaa aagattgagg gaactagaaa tggtaagttt
    15961 ggagaaataa tgcctcaaga tgagttcata gctttaatgc aaataagtga tgcatttgat
    16021 ttagtaaaat tatcacaaga atttattgat gaagtaaagc caaaaatcga aaataactac
    16081 cctgaaattg caccatttgt aggtaaatta aagggtgatg atatagaaga aggtaaagaa
    16141 ttagtagcaa cacacatagc tgaaggatta taccatgatg gaaaatttgt tggttatgta
    16201 aaaagagcac atgatgtaga tgttaactta aatgcccata caatgtttga aaatctagta
    16261 gtaaaagcat ctggagtttt atctgctatt caaatgctaa gacatagcaa aatagaccct
    16321 gctgaaatag attatgttat tgagtgttca gaagaagctt gtggagatat aaaccaaaga
    16381 ggtggaggaa actttgctaa atcaatagct gagatagcag gacttcagaa tgcaactggt
    16441 tctgacacaa gaggattttg tgcagcacca actcatgcat taattcaagc agcagcttta
    16501 gtaaaagctg gcatacataa aaatgtaatg gtagtagcag gtggagcaag tgctaaactt
    16561 ggaatgaatg ctaaagacca tgttaaaaaa ggtcttcctg tacttgaaga tgttgttgga
    16621 ggatttgcag tacttgtatc tgaaaatgat ggtgtaaatc cagttataag aactgattta
    16681 acaggtaagc atactgttgg aactggttct tcaccacaag cagttatgac agcacttata
    16741 acttcaggtc ttgatagagc taatttaaaa ataacagatg ttgatgtgta ttcagttgaa
    16801 atgcaaaacc cagatataac taagccagca ggagcaggag atgttccaga agcaaactac
    16861 aaaatgatag gggcacttgc tgttaaacgt ggagacttag aaaagaaaga attgaaagat
    16921 tttgtttcta acaaaggatt accaggatgg gcaccaactc aaggacatat accatcagga
    16981 gctccttata taggattttt aatagatgat ttaactacag gaaatagaaa tagagctatg
    17041 atagttggaa aaggtagttt attcttagga agaatgacta acttatttga tggagtatct
    17101 tttatagctg aaagaaatac aggtgttact gaagagactt caggaatatc taaggatgaa
    17161 attaagaaga taatagctga atctatgaaa aaactagcat tagatatgtt agaagaatag
    17221 gggtgaggat atgtcaaaaa aagtaatcgc agatgtattc ttagaagtag ctaatgcaat
    17281 agaaagcggc gaatttggca aaaaagtaaa aattggtgtt actacacttg gaagtgaaca
    17341 tggtgtagaa aacatggtta atggtgcaca attagcaaaa tctaatttat ttgatattgt
    17401 gcttattgga ccaaaagtgg aaactgacct tgaagtagtt gaagttaatg atgaaaaaga
    17461 aatgcatgca aaaatggaag aattattaga ttcaggatat attgatgctt gtgttactat
    17521 gcattataat tttccaatag gtgtatctac agtaggtaga gtaataactc cagcaaaagg
    17581 aaaagaaatg atacttgcaa caacaacagg aacaagtgct actaatagaa tagaggcaat
    17641 ggtaagaaat gccatttatg gtattgctac agctaaatca atgggtaaca aatgcccaaa
    17701 agttggaata cttaatgttg atggagcaag acaagttgag aagtgcttaa aagaattaaa
    17761 agataatgga tatgacatgg agtttgcgga ttcaattaga gcagatggtg gatgtgtaat
    17821 gagaggtaat gatttacttg taggtgcacc tgatgttatg gttactgata cattatctgg
    17881 aaatatattt atgaaagtat tttcttcata tactacaggt ggagattatg aagctcaagg
    17941 ctttggatac ggacctggag ttggagaaga ctatgataga aaggtactta tagtatcaag
    18001 agcatcaggt tctccggtag tagcaaatgc tttaaaatac gcttatgatg ttgtaaaggg
    18061 agatataagt aatgttgcaa gaaatgaatt tgcaaaggtt aaaaaagcaa aatttgatga
    18121 cattatatcc tctcttacta aaaaagaagt taaagctgaa aaagtagaag ttaaaatgcc
    18181 agataaagaa attgttactc gtcaaatagc tggtgttgat ataatggatt tagaagatgc
    18241 agtatctgag ttatggaaaa acggaatcta tgctgaaagt ggtatgggtt gtacaggtcc
    18301 aatagtttta gtaaatgaag ctaaaggaga cttagcagtt gaaactttag ttaaagctgg
    18361 atatactgca aaataagtac attttttata tgtaaataag aacatatagt tataatttta
    18421 ttgattataa ttatatgttc tttttatttt atatcttgtc aatatttata tattaacaca
    18481 atccatttat ttgattctct agctaattta ttatatttat tcaattaaaa ttaagctttc
    18541 taactaaata aaaactaatg aagtattaaa atgaaattaa taaaatatga aaaaatttta
    18601 ggaataaagt atctgttaga taaaaataag attaattagt gatataatat aattaagata
    18661 aaatttatta tttggaggta aaatcatgag cagagtaaaa aatgtagtag gattgttggg
    18721 aactaaaggt gttgatgcac tatatctaac aaagaaaact aatgtaaact atataagtgg
    18781 ttttcctgat gaagaagcat atgcagtgat ttgcaaagat ggaaactttt tagttactga
    18841 tagtagatat atggagcttg cagaaaaggt ttgcaaagat tttgaaatta taaattggca
    18901 taattttgat agaagtgtgg caaaggcagt taaaagtgta tgtgataaag tgggtataaa
    18961 gaaacttggg tttgaaagaa ctaatatagt gtttgataaa tatgaagaac ttaaaaatct
    19021 gattgagaag gataatggag aattaatacc tacagaaaat attgtagaga ctttgagata
    19081 tgtaaaagac aaagatgaaa tcaaaaatac aagaaaagct tgtgaaatag cggataaggc
    19141 attagaagaa ttgattccac atataaaagc tggagttagc gaaattgaac tggctacaaa
    19201 gttagagtac tttatgaaaa tgaacggagc acaaaatata gggtttgaaa ctatactgat
    19261 atcaggagca aagacttcat tgcttcatgg taagcctagt gataagatta tagaaaaagg
    19321 tgattttgta cttatagact atggtgctat gtataatggc tatatatctg atacaactag
    19381 aacttttata gttggaggag cttctgaaaa gcaattagaa atatataatt tagttaagga
    19441 agctcaaaat gtaggggttg agaacatgaa agctggtgta catgcgacaa ttccagatgc
    19501 tgagataaga aaagttgtca aaaaatatga agactattac tatcaaggta taggacatgg
    19561 agtcggtagg gatgttcatg aagaaccttt cattggtaat tatggtgata aaatcataga
    19621 agagggatgt ataataacaa tggaaccagg tatttatttc cctggatggg gtggagttag
    19681 aatagaagat actgttttga ttactaaaaa tggtccagaa agacttacta aattccctaa
    19741 agatttgatg attttagaca aataatttaa tttatatata tttttttaca taaaatataa
    19801 cataatctca ctattaagct ctatttacat attatagtaa agagggctta attttattgt
    19861 aagaggtgat agtatatatg tataaaaaac ataaatttat aaaaaatata aaaaaagcct
    19921 ggtataaaat caaattaatt gatagatgcc ttataattgt aatggcaata ttaatgtttc
    19981 aatctatata taatttattt gttaatgaag taaattcaca agatactaca actattgatg
    20041 tagtagtaag aaccacttca gcagctatat ttgggtattt tttaagtgct aattttataa
    20101 agagaccttt aaggaagtat acaaatactg atgtatcttc aaatcttttt atagataata
    20161 atttaccccc aaaaggtcaa gagtctagtc aaaataatat aatgaatgtc aaaaatacca
    20221 ttggatttac ttcagaagct gataattatg aaaagaaaat acctattaat aataatgaag
    20281 gttttgaaga aggagaaact agtgaattgc aaattattat agctactgta atttgtatag
    20341 cagcattaac agtacttttt gttgtaagaa attttacaac tacaacatca gcttctttag
    20401 gtactatttc acagatgaga gattttgtct caggatgcgt gggttttttg ctaggttgtc
    20461 caagtaaacc tgattaaaaa agtattatca ataaaaggta ttttaaaaag tatcagtata
    20521 ataatattta gatttaaatg tatacaatta taattctata acattctata ttgtattttt
    20581 atactgatac tctaaactat actatttatt aaaatatttt aacattgtat ttaaacaaaa
    20641 tattatatct gtataatata aatttagttt atatgaatag atgccatata ctcaataaaa
    20701 agtttcatac tatgagatat gtattgattt cttctccaaa gaactccaat atttgcagta
    20761 attgcacgtt ctaatggtat tgaacagaga ttttctgtat tttgaaatat ttctttatac
    20821 aatattgttg aagccaagtc attttctagt aaataacgta tggtagaaag ttgatttgag
    20881 tgtaaaatta tatttggctt agctttttca agtctttttg taataatctt atagtgataa
    20941 gaaccttcag ataagattac aaaaggtaca ttttttaaca tataatttga tataatggga
    21001 tgttttgcca attcattttt gggatttgta actaagtaca attctgtttt atagattgtc
    21061 tttgaatcta tatcatcata aatatcactg tcaattatac caatacaaaa atcaagtgta
    21121 gattcttcaa tcattttagc tccaacaaat gttggaactt caaaaatttt aagctctata
    21181 tctggataaa ttacattaaa tctaggaagt atttttgaaa gcaaaaacgt acctaaaact
    21241 gtaggaatac ctattttgag agaagctttt ctcttttttc ctaaatcaag tgcgtcacat
    21301 tgaaaatcct caaattgttt tataaaatgt tttgacttgt ctaaaaaaat ttttccttca
    21361 ggcgttaatt ctattttatt acctattctg taaaaaagtt caaagccaag ttctttttct
    21421 aattctttaa ttgctaatgt tatggatggt tgagaaatat gaatactttc cgcagcctta
    21481 gtcatgtttt tatatttaca gacagtttga aaatagtata aatagtttat attcatttgg
    21541 tattagttcc tttcatttac atattagtga caagtatata attaacaata gcataagttt
    21601 tgtatattgt tgtaaaaaaa tagaatagtt ttaaactatc atagcataag tttttgatat
    21661 tttcaatcta ttaagaatag tgctattatt aaattaacaa aagagaatag ctggtatggt
    21721 ttagagtaaa tcaatctata ttacagttat atcaacgaat atcaaaaaat tatctattag
    21781 aaaataaaaa ttatttttac aattaaattg ttaattaaat cataaagaaa aaagtgatat
    21841 taacaagata aaattttttt aatcagaaat gttaatttaa taacaaaata gagtattggg
    21901 gagaaaggag aaatatattt tttaataata tttgttaatt taataacgaa aaatgaaagg
    21961 gagtgattta gtgaagtttg aattgatgga ttttttaatg aatccttttg tccttatgtt
    22021 tgctgcagta attacaggaa ttttatttgg aaaaattaaa tttgggaagt ttaattttgg
    22081 ggtatcagga gcattattta caggattatt tattggatgg cttgcatata gcttggggaa
    22141 tctaataata gcaaaaggag aaacagcagc aggatataag gcagcaactg taatgatggg
    22201 gaatggaatt atttcttctg acttctttga tttcttttta ataatatttg ttgcagcagt
    22261 tggtctattg gcagcaaaag atatgaaagc tgtattaaag aagtatggag caagatttgt
    22321 aattttagga gttcttataa cttttatagg tggctctatg acttatgcaa tgactttact
    22381 atcaagtgat aaaggaagta gtgcttatga agtttctggc gtttacacag gagcattaac
    22441 aagttcgcct ggattagctg ctgctttaga aacagctggt aaacatgcag aagatgtatc
    22501 aaaagaattt gaaaaagctt caataaaaga taaaaaagaa attttaaaag tagtcgaccc
    22561 agaaggcaaa ttggatgtga atacaactac atcactgact caagagcaaa tagataagta
    22621 tattgcatat gctgaagctg gtgttggtat aggtcatgca gtcgcatatc cttttggagt
    22681 tttaatagta atcttaggtg taaatttcct tccaaaatta tttaggatgg acctaaaaga
    22741 agaaagaaga aaatatgaga aggaaatgaa ggaagcaaga gatagtgttt ctggtaaaac
    22801 gataccagaa gttccattta atataataac atttttcttg acatgtttag ctggatactt
    22861 agttggagga atacatgtat ttatgggacc actagggtac ttcacactag gcgcaacagg
    22921 aggttcacta attgtatctc tagttcttgg atatataggt aagatagggg tagtaaattt
    22981 cagaatggaa gaaaaggttt taaatatttt aaaacaaata gggctagtat ttttcttagc
    23041 aatagttgga ttaagatatg gtggaaaagt agttgattca attatgacat ctggtatgca
    23101 cctagcctta gtagcaatag cagtaggtgt tacagctatg atgataggat tcttagttgg
    23161 caaatacgta tttaaattaa attggatttt attatctgga gctgtctgtg gtggtatgac
    23221 atcaacacca ggtcttggag ctgctgttga tgctcttgat agtgatgacc cagcagcagg
    23281 ttatggtgct acgtatccat ttgcattatt aactaaagtt atattggtta tagttttaca
    23341 caaacttcca atgtaaataa gattttatat ggggggatat ttatgaataa tgaaggagca
    23401 tttgaagaat taagtggaag attaagaaat aaagaattgt gtgatttaat aatgaatgca
    23461 gatgaagctg ctaaaattat agaggatggc atggttattg gagttagtgg atttacacct
    23521 tcaggctatc caaaagcagt accattagca gtttcagaaa gagctaaaag tggagaaaag
    23581 ataaaattaa ccgtatattc aggagcatct ttaggcccag aagttgatgg agcatggtca
    23641 gaagcaggta taattgaaag aagacttcct tatcaaacta attcaatact tagaaataat
    23701 attaataaag gtgttgttga ttatatagat atgcacctaa gtcattctac tcaattttta
    23761 aattatggaa ctatacctaa agtagatgta gctatagtag aagcacttgc aataactgaa
    23821 gaagggaata ttataccaac tagtgggata ggtaattctc catcttttat aaaaagtgca
    23881 gataaagtaa tagtagagat aaatcttgca aaaccaatgg aaatggaagg tatggcagat
    23941 atatatatta cggaaaatcc accaaataga aaaccaatag aaataaatca tcctaaggat
    24001 agaattggaa caacatatat accttgtggt ttggataaaa ttgcaggagt agtaattacc
    24061 aatatgcaag ataagacccg tccattgggg gttgtagatg aagcttcgaa aaaaatatca
    24121 aataatatta ttgctttttt aagagaagaa gtaaaggcag gcagattatc aaagaattta
    24181 cttcctcttc aatctggtgt aggaagtgta gcaaatgcag tattatatgg attatgtgaa
    24241 tctgaatttg aaaatttaac ttgttataca gaggttgtac aggactctat gttggattta
    24301 ataagaatgg gtaaagttac aatggcatct actacatctg taagtccatc tccagaagga
    24361 ttaataaaat ttgaaaaaga tattgatttt tttaaggata agattatatt aagacctcaa
    24421 gaaattagta acaatccaga aatagccaga agaattggtg taattgcaat gaacactgca
    24481 attgaagttg atatttatgg aaatgtaaat tctactcaca taatggggtc aaagatgatg
    24541 aatggaattg gaggttctgg tgattttgct agaaatggag caataactat atttagtact
    24601 gagtcgattg caaaaaatgg tgatatatca tcaatagtac ctatggtatc tcacgtagac
    24661 cacactgaac atgatgtaat ggtaattgta acagaacaag gatatgctga tttaagaggt
    24721 cttgcaccta gagaaagagc tataaaaata atagaaaatt gtgcccatcc agattataaa
    24781 gaacaactta gggattattt aaatagagct tgtaaaagtg gagcaaaaca aacacctcac
    24841 atattggacg aagctttatc atggcatagt aaatttatga gtacaggtac aatgaaaaag
    24901 gctgaaactt ttaaaagtgc attataaaat atttaataaa ttggaggtag attttaaatg
    24961 gaaaaagcag tggaaaactt tgaagattta agtaaggaat acattaatgg ttatattgag
    25021 agagcaagaa aagctcaaag agagtttgaa tgttatactc aagaacaagt agataaaata
    25081 gtaaaaatag ttggaaaagt agtgtattat aatgctgaat atttagctaa acttgctgta
    25141 gaagagactg gaatgggagt atatgaagat aaggtagcta aaaataaaag caaagcaaaa
    25201 gttatatata acaatttaaa agataaaaaa tcagttggta taattgatat agatagagaa
    25261 actggaataa caaaggtagc taaaccagtt ggagtagtag cggcaataac tccttgtaca
    25321 aatccaatcg ttacacctat gagcaatgca atgtttgcac ttaagggaag aaatgcaatt
    25381 attatcacac ctcatcataa agcaattgga tgtagtacaa aaactgtaga gatgattaat
    25441 gaagaattag aaaaaatagg agctccagaa aatttaatac aaatacttga ccaacaatca
    25501 agagaaaata caagaaattt aatttcatca gcagatgtag taattgccac tggaggaatg
    25561 ggaatggtaa aagctgcgta ctcaagtgga aaaccagcac ttggtgtagg ggcaggaaat
    25621 gttcaatgta tcatagatag agatgtagac attaaagaag cagtacctaa aatcatagca
    25681 ggaagaattt ttgataatgg tatcatttgt tcaggtgaac agtcagtaat agtagcagaa
    25741 gaaatgtttg ataaaataat ggatgaattt aaaaataaca aaggttttat agttagagat
    25801 aaagtacaaa aagaagcttt cagaaatgct atgtttgtaa ataaatctat gaataaagat
    25861 gcagtaggtc aatcagttca tacaattgca aaaattgcag gtgttgagat accagaagat
    25921 acaaaaataa tagtaataga agctgatgga ccaggagaag aggatattat tgcaaaagaa
    25981 aaaatgtgtc cagttatatc tgcatacaag tataaaagtt ttgaagaagg tgtagctatt
    26041 gcaaaagcaa atttaaatgt agaaggaaaa ggacatagtg tatctataca ttcaaataca
    26101 gttaaaaata tagaatatgc aggagaaaat atagaagtat caagatttgt tattaatcaa
    26161 tgttgtgcta ctagtgctgg aggaagtttc tttaatggtc ttgcacctac taatactcta
    26221 ggttgtggtt cttggggaaa taacagcatc tctgaaaatc ttgattataa gcatctaatt
    26281 aatatttcta gaattgctta ttatatgcca gaaaatgaag tccctacaga tgaagaactt
    26341 tggggataaa acttagacaa aaaatattca ttctaaatta aagtaggaat atattttaat
    26401 ttagaatgaa tttaagacat aaattaaatt taaattagtt tattggacta aatttaaaat
    26461 attaagagac atatagaaga aggaagtatt ataatttaaa ataaataaaa aaatctataa
    26521 aagagaagga gtggttttat tatggcatta atgacaggag ctcaatatat tgaaagtttg
    26581 agaaaattaa atactaaggt ttatatgttt ggtgaagagg ttaagaattg ggttgaccat
    26641 cctatgatta gaccatctat aaattgtgta gcagcaactt atgacttagc tcatgaccca
    26701 gaatatgcag atttaatgac agttacttca aatatcacag gtgaaaaaat aaatagattt
    26761 ggtcatcttc atcaaagtgt tgatgatttg ataaaaaaag taaaaatgca aagactatgt
    26821 ggtcaaaaaa cagcttcttg tttccaaaga tgtgttggta tggatgcgtt taatgcagtg
    26881 tattcaacaa catttgagtg tgataaagcc catggaacta attatcatga taattttgta
    26941 aaatacttaa cttatataca agaaaacgat ttagtagttg atggagctat gactgaccct
    27001 aagggagata gaagtctatc acctagtgct caacctgacc cagatatgtt ccttcatata
    27061 gtagaaagaa gagaagatgg gataattgta agaggagcaa aggcacatca aactggttca
    27121 ataaattcac atgagcacct tataatgcct actataagta tgactgaagc agataaagac
    27181 tacgctgtat catttgcagt tccttcagat gctgaaggtg tgtttatgat ttatggaaga
    27241 caatcttgtg acaccagaaa attagaagaa ggtgcagatg ttgatttagg aaataaggag
    27301 tttggaggtc aagaagcttt agtagtattt gataatgtat ttgttccaaa tgatagaatt
    27361 ttcttatgtg gagaatggga tttctctggt atgttagtag agagatttgc aggataccat
    27421 agacaaagtt atggtggatg taaagtagga gtaggtgatg taataatagg agcagcagct
    27481 ttagcagctg attataatgg agcaaacaaa gcttcacata taaaagataa actaatagaa
    27541 atgactcacc ttaatgaaag cttatattgc tgtggtatag catgttcatc agaaggtcac
    27601 aaaacagaag ctggaaacta tcaaatagat ttacttcttg caaatgtgtg taaacaaaat
    27661 gtaactagat ttccttatga aatagtaaga cttgcagaag atatagctgg agggcttatg
    27721 gttactatgc cttcagaaaa agactttaaa tcagacctta aagttggaac aagtggaatg
    27781 actattggcg aagtatgtaa caagtatttt aaagcttctt cagtggcttc aacagaagaa
    27841 agaatgagaa tattaagatt cttagaaaat atatgtcttg gttcatctgc tgttggttat
    27901 agaactgagt caatgcatgg ggcaggttca ccacaagctc aaagaataat gatttcaaga
    27961 caaggaaaca taaatcaaaa gaaagaatta gctaagaaaa ttgcgggaat aaaaaaagag
    28021 gaagctttaa atttataaaa agttgatata taaagggaaa ttatatatta atgtgtatta
    28081 attaatgaaa agatatgtag tataagagat agttataaaa ttatggtggt ttttagctaa
    28141 gtaaagaaat ttttaataag gagaatttac acatgacctg tggagttaga ttttgtgggg
    28201 gctgtaaccc tagatacgaa agagggaagg ctcttacaat aatcaaagag cacttcaatg
    28261 gtagggtaga ttttagcata gcacaagaga acgtcgagta tgatttgcta cttataattg
    28321 gaggatgcgc aactctatgc gcatcctatc aacaatataa agtgaaaaat gaatgtgtta
    28381 agatgtggga ttttagccat atagaaagag ttataaatgt gattgaatca gcaatttgtg
    28441 aaacttaaaa aagctaaatg gggggatttc attgagttgg caagaattgt atcaaagtaa
    28501 attatgtagt gctacagaag ctgtaaaaca gattaaaaac ggtgatactg tagtatttgc
    28561 acattgtgta ggtgaacctc ctgcactagt agaggctatg attgaaaatg ctgaacaata
    28621 taaagatgtt gagattaaac atatggtaag cttgggtagt ggtggatata ctgctaaggg
    28681 aatggaagct cattttagag taaatccaat gtttgtaagt ggaaatgtaa gaaaggcaat
    28741 tgaaaatgga gatggtgatt ttacacctgc attcttccat gaagtaccaa agttgcttag
    28801 agaaaaaaga ttaaaatgtg atgttgtttt agcacaggta actccaccag atgaacatgg
    28861 gtattgtagc ttaggaacat cagttgatta tacttatgaa gccattaaaa ctgctagaac
    28921 agtaattgtt caagtgaatg accagtttcc tagaacctat ggtgaggtag tccatgtatc
    28981 agagtttgac tatatagtgg aaaaatcaca acctttattt gaactacaac ctgcaaagat
    29041 tggagaagta gaagaagcaa ttggtaaaaa ttgtgcttca ttaattgaag atggttctac
    29101 tttacagcta ggtattggtg ggataccaga tgcagttatg ttatttttaa ctgataaaaa
    29161 ggatttaggg attcattcag aaatgatttc agatgggact ttggcccttt atgaaaaagg
    29221 tgttataaat ggtaaatata aaaattttga taaagaaaaa atgacagtta ccttcttaat
    29281 gggtactaaa aaattatatg actttgcaaa taataaccct gcagtagagg taaaaccagt
    29341 agactatgtg aatcatccag caattataat gaaacaacat aagatggttt ctataaattc
    29401 tgctatacaa gttgatttaa tgggacaggt agttgcagag gctatgggac ttagacaatt
    29461 tagtggtgtt ggaggtcaag ttgactttat acgtggagtg tctatggggg aagatggaaa
    29521 ggcaattata gctatgcctt caataactac aaaaaaagat ggtacagtaa tttcaaaaat
    29581 cgtatctatt gtggatgaag gtgcacctat aacgacatca agaaatgatg ttgactatat
    29641 tgtaacagaa tacggtatag cagaattaaa aggaaaatct cttagagaaa gagcaagaaa
    29701 tttaataaat atagctcatc caagtgtaag agaaagtcta gcagtagaat ttgaaaagag
    29761 atttaaggag aaatattaat aatagagggg tgttaataat ggaagcactt agagtagttc
    29821 caaagatatt ttattttgat acatttaaag aatttaatga agaatttaaa ataggaaaaa
    29881 atgatttagt aattactaat gagtttatat atgagccata tatgaaacct cttggaatag
    29941 atacaaattt aatttttcaa gaaaagtttg gaacaggtga accatctgat gaaatgatag
    30001 actccatgac aaaggaaatg aagaaataca attttgatag aattattgcg tttggaggag
    30061 gaacaatagt tgatatatgt aagatattag cacttgatgt tccagaaaag tctattgatt
    30121 tatttgaagg agaagtatca cctaaaaaag taaaagagtt agtagtagtt cctacaacat
    30181 gtggtacagg tagtgaagta acaaatgtag ctattgcaga gttaaaatct aaacatacta
    30241 aaaaggggct tgcagtagaa gaaacatatg cagactatgc agtgttaatt ccagagacag
    30301 taaaagggtt accttacaaa ttctttgtta caagttcggt agatgctctt atacatgcta
    30361 ttgagtctta tctttctcca aaagcaagtc catttacaga gatgtattct ctacaagcaa
    30421 taaaaatgat tatggatggg tataagaaga tagttgataa aggagaagaa gagagattta
    30481 atcatcttag agactttgta cttgcatcaa attatgcagg aattgctttt ggaaatgctg
    30541 gttgtgcagc agttcatgca ctatcttatt caataggtgg agctttccat gttgcacatg
    30601 gtgaagcaaa ttatcagttc tttactgaag tatttaagat gtattctaga aaaaaaccta
    30661 atggaaaaat tataaaatgt acaaaaattt tagcagatgc ccttgaatgt gaccctaact
    30721 gtgatgttta tggagaatta gaaaagtttt taaataaatt aatagctaaa aaagctttga
    30781 gagaatatgg aatggtggaa agtcagatag atgaatttac agatagtaca atagcaaatc
    30841 aacaacgact acttgctaat aattatgtag agcttagtag agaggaaata agagagatat
    30901 ttgcaaatct ttattaatac aattttttat ttatatgtat agtcaacata aacaatgcta
    30961 attatattta tgtacaaata aaaataaggg aacttaaatt ttaattaaag ttaagttctc
    31021 ttatttttat atggagttaa atataagtat atttttaatt taaaatatgc ttatatttaa
    31081 gtctattact ttatttgaaa caatttgtag aatttcaaat tccttgacag taataagtaa
    31141 gtaattgtat aatcaaactg caatatatta ataatattag tgaaaatgaa aggattataa
    31201 aatatgtata aatcagaaaa tttttcaaaa aaatctgtat taataaattc atttttaagt
    31261 aaatttttaa aaataattgg atggggtttg gtaagcttat ttacattatc agccttagta
    31321 ctttcaacta tttccattat aattggatgg gctgtaatac ttcctattca agtatgtgca
    31381 gtatttttac ttataggagg agtttgtatt tttaaaggta agagattagg agaccaaatt
    31441 tctcgttata aaaaatattg tacaattata aacaatagaa atattattcc agtagaactt
    31501 attgcagaaa acacatctaa atcattaaat tttataataa aagatgtaca aaagatgata
    31561 gacaaaaact actttataaa tacttatatt gataaaagaa ataatcagat tgtgttaaca
    31621 aatgaagatt ttattccacc aagatatgaa gatgtagcat atgaagtcaa agaagaagaa
    31681 aagactgatg aatccaatga agttgataca attataaata aaggaatgaa ttatctaaca
    31741 caaataaaag aagctaataa aaatattaaa tcagaatcaa tgggcgataa aattgtacaa
    31801 gtagaagatg ttacaagtaa aatatttgat gttgtaaaac atgacccatc aaaacttact
    31861 caaatacaaa aatttatgga ttattatctt ccaaccactt taaaactatt aaattcatat
    31921 catacattgg aagaacaagg aattgataga gaaaatataa caacaactat ggaaagtatt
    31981 gaaaatacaa tgaatacgat tgtagtagct tttgaaaatc aattggacta tctgtttgaa
    32041 gatgaagcca ttgatatttc tacagatatt actgttttag agaatatgtt agtccaagaa
    32101 ggattaacga gtggtaaatt ttaacttcaa tagaaaaaat attctgttat ttttaaacaa
    32161 ttaattagtc ataaagtata aaatgtgtat tatataagtt aatcagtact ttatgaagga
    32221 agaggagaga aagatacaat gaataattta gatgatatac cagttatgcc aactttgaca
    32281 cttgacccat ttggagaaga atcaaacact aatgatatag ataattctga cttattaatg
    32341 aaaaaggatg aaaaagaccc agaagaagaa aaactgtctg aatctgaacg caagatggta
    32401 aaggaatttg cggaaaaaat agatattaca aatacaaata tgattttgca atatggagct
    32461 ggtgctcaaa aaaaggtagc aagtttttct gaaacagctt taaagagtgt aaaaacaaga
    32521 gatttaggag aagttggaga tatgcttaca aatctagtta ctgatttaaa agcattttca
    32581 gcagatgaaa aagaacaaag tggtttttta ggaattttta aaaaggcaaa taataaaatt
    32641 tcaaatttaa aaactaagta tgatagtgca gaggtaaatg tggataaagt aagtaaagag
    32701 cttcaaaagc atcaggttaa aatattgaaa gatatagcaa tgcttgataa gatgtatgaa
    32761 ttgaacttag cttactcaaa agagcttact atgtatatta tagcaggaaa acaaaaatta
    32821 aaggatatga aagaatatga aatgccaaag ttgagagaaa aagctcgttt atctggttca
    32881 acagaagatg ctcaatctgt aaatgatatg gtttcacttt gtgacagatt tgaaaagaaa
    32941 attcatgact tagaattaac tagaatggta tcgcttcaaa tggctcctca gataagattg
    33001 gttcaaaata gtaataatct gatggcagaa aagattcaat caactatagt aaataccatt
    33061 ccattatgga aaaatcaaat agtgcttgct cttggaattt ctcacttaaa tcaagctatg
    33121 aaagcacagc gtgaagttag taatatgaca aatgagcttt tattgaagaa tgcagaaact
    33181 ttgaagatgg gaacaataga aacagcaaaa gaatcagaaa gaggaattgt agatatagac
    33241 acaattaaga aaactaatca atctctaata tctactattg atgaggtagt taaaatacaa
    33301 catgatggta gaataaagag acaagaagca gaagttgaat tatcaaaaat agaaaatgaa
    33361 cttaaaagta agcttcttga atttacagtt aaataaaaat tatactaata taaaaagaga
    33421 ctgtctcaaa atagagataa gtctcttttt cattgtttaa atgattaaag tatatttata
    33481 ttataaattt ctattatctt ttaacataac atcatgagct ccaccttcaa ctatactagt
    33541 agaagataca agtgtaagtt tagcattttt ttgaagttca ggaatgctaa gtgctccaca
    33601 gttacacata gtagaacgaa ctttacttaa agaaagagtt acattgtctt tcaaagaacc
    33661 agcataaggc acataagagt caacaccttc ttcaaaagaa agtttcttat ctccaccaag
    33721 gtcatatctt tgccagtttc tagcacgagc agaaccttct ccccaatact ctttcatata
    33781 actaccattt atattaactt tgttagttgg actctcatca aaacgagaga agtatctacc
    33841 aagcattata aaatctgcac ccatagctaa agctaaagtt atatgatggt cataaacgat
    33901 accaccatca gagcaaattg gaatataaat acctgttttt tcaaagtatt cgtctctagc
    33961 ttgagcaact tcaattatag aagtagcttg tccacgtcct ataccttttt gttcacgagt
    34021 tatacatata gaaccaccac caataccaac tttaacgaag tcagcaccag cttcagctag
    34081 gtaaaggaat ccctcgcggt caactacatt tccagctcct accttaactg tatcaccata
    34141 tttttcacga atgaaatcaa gtgttatttt ttgccactca gaaaaacctt ctgaagaatc
    34201 tatacataaa acatcagcac cagcttcaac taaagcagga acacgttcag caaagtctct
    34261 agtattaata ccagctccaa ctacatatct cttagaagaa tctaaaagtt caagtggatt
    34321 ttctttatga gaagagtaat ctttacggaa taccatatac ataagattac cattatcatc
    34381 aagtacagga agagaattaa gtttgtggtc ccatataatg ttgtttgctt cctttaaagt
    34441 aacatctttg ttagcataaa ctatagatga cataggagtc ataaattcac taactttagt
    34501 atctaaatcc atacgactta tacgataatc acgacttgca acaataccca ataatttacc
    34561 agttgaagtt ccatcttcag taacagctac tgtagaatgt ccagtttttt cttttaagtc
    34621 aagtatgtct tttaatgtgt tatcaggttt aatatttgaa tcacttacaa caaaaccagc
    34681 tttgtgggat ttaacacgtg ctaccatagc agcttcattt tcaatagttt gagaaccgta
    34741 tataaatgaa ataccacctt ctttagcaag tgcaatagcc attttgtcat cagaaacaga
    34801 ttgcataata gcagaagtca aaggtatatt catataaata tctgcttcct cgcccttttt
    34861 aaatttagta acaggtgttt ttaaacttac attagcaggt atacaatcag tagaagagaa
    34921 acctggtaca agaaggtatt cactgaaagt atgtgatggt gtatcaaaat aaaacgccat
    34981 tttttaatca ctccttatat ttttatactt tttataattg atagtattaa ttataactta
    35041 ttctttaatt ttattaaagt attttgtcaa atattgagat ttttgaaaaa tttaaactat
    35101 tttaattaaa tttgtttaat atatattgcc ttatagggta aagttgtata ttaaataatg
    35161 tttagtgttt aatagtagct aatttaaaat taatctttag tgattcatat aattacattt
    35221 gtatagttta tattgataat attactagag agtgcataaa cctcaaaaat acagataaat
    35281 taaatctata ttagtatatc caaaagtaca tttaataaat ttatttaact gaattattat
    35341 tttcatttct attaaattta aatattttat aaaaatagta ttatttacaa aatcatatac
    35401 tccaaaatac tacataaata aaattaaaca aaaactaaaa tgacaaatgt cattatctaa
    35461 agtgacatag aaacggtttc ttaaagttgt tactataaaa tataaactct ataataaaag
    35521 tataacaaaa gggaatcata tcgatataga atataattca agaggaggta aaattatgag
    35581 tagttctaat caatcgacaa taaagacatc tatacagcga gtagggaaat ttttaagtgg
    35641 tatggtaatg ccaaatatag gagcttttat agcatggggt cttataacag cattatttat
    35701 accaacagga tggatgccta atgaaaaatt gagtactata ggcgacccaa tgataaaata
    35761 ccttttacca ctattgatag cttatactgg tggtaaagca atagcaggac aaagaggtgg
    35821 cgtaataggt gcagcagcag ctatgggagt aattgttggt gcagatatac caatgtttat
    35881 cggagcaatg ataatgggac catttgcagg atgggtaatt aagaagtttg ataaatttgt
    35941 agatggaaag ataccaacag gatttgaaat gttagtaaat aacttttcaa taggtataat
    36001 aggtatgctt cttgcaatac taggatttta tgcaattgga ccagcaatag tagcagggac
    36061 agctcttata gaatctggag ttcaatttat agttagcaaa agtttattgc ctctagtttc
    36121 agtatttata gaacctggaa aagtattatt cttaaacaat gcaataaatc atggtatatt
    36181 agggcctata ggtatagctg aggcaaaaga agcaggtaaa tctataatgt tcttactaga
    36241 aagtaaccct ggaccaggtt taggagttct attagcatat tggatgttta gtagaggaag
    36301 tgtaaaacaa tcagcaccag gagctgtaat aatacatttc tttggtggta tccatgaaat
    36361 ttacttccca tatattttaa tgaatccagt tttaatattg gctacaatgg caggtggagc
    36421 agcaggaata ttgacttttt caatattagg agctgggctt gtagcagcac catcaccagg
    36481 aagtatattt gcacttatgg cactagctcc aaagggagga ttacttccag tattagcagg
    36541 agttgcagtg gcaacagttg tatcattctt agtggcagca ccatttgtta agagagcttc
    36601 agcaaatcaa agtgaagaag acagtacttc tttagaagaa gctaaagcaa aaatgagtga
    36661 tatgaaatct gcaagtaaga actctgagaa aaatattgag gaaaaacagc ttgaagtaaa
    36721 tgagattaag aagattgtat ttgcatgtga tgcaggaatg ggttcgagtg caatgggagc
    36781 ttccagattt aaaaatagaa taaaaaactt agacttaaat atagaaatta caaattcatc
    36841 tgttgataat cttccagatg atacacaaat agtagtaact cacaatacat tagttgaaag
    36901 agttgctaag aataattcaa gtgttgagat agtttcaata aacaattttt taaatgaccc
    36961 aaatttagat gcattattta aaagattaga atctaaataa aaataaaaag taccactaat
    37021 taggagtgga taatttgaaa aaaaagaaga ttacatctag gcaaaaaaag ataatactaa
    37081 tgatagtaga aaattcaaag aaaaacattc caataactat ttctgagatt gcagggactt
    37141 tagagctaag ttcaagaact gtacttagag atatgtctgg aattgaaaaa tggtttgatg
    37201 aaaatgattt taactttgta aaaaaaccag gagtgggatt gattttagag gaaaatatag
    37261 aaaatcaaaa ctttataatt gagttgttag aagaagaaaa aatagaaaaa gaatacagca
    37321 aggaagaaag aaatttaatt atattatcaa agctactagt ttctaacgag ccagtaaaat
    37381 cctattattt tgcaaaaata ttaaaggtat ctgaaggggt actgaataat gattttgcct
    37441 tagcaagtaa atggttggaa agatttgata ttgagcttgt tagaaaacca gggcttggtg
    37501 tctacttaaa aggtcaagaa aaaaacttta gagaggcata tgtaaatctt atatacgatt
    37561 cattcaatga aaaagaaata ctagatatgg tcagaaatat aagtgaaaat atacaaacag
    37621 ataaagcaat agaaatttta agtgaaaata gacttttaaa tttaatggac aggtgcataa
    37681 taagaaaagt tgaagctaca ttaacaaaga agctttcaga tttagatgta aatttagctg
    37741 atagtgcata tatagggctt gtagttcata tttcattagc cttacagagg ataaaaaatg
    37801 gtgaaaatat aactatggat aaagagtttc taaaagaatt atctataaca gaagagttta
    37861 aattagctaa agaaatcgta aaaggtatgg aaacagattt taacatggat ataccagtag
    37921 atgaggttgg atatataact atgcatataa gaggtgcaaa gcaaaggtca tcttcaaacc
    37981 ataaggcttt aaacttagat gatatagaaa taatggaaat tacaaataag atgatagatt
    38041 tggcggaaga tgaatttaaa ataagtttaa aaaatgacga gaggttattt aaagacctag
    38101 caaatcactt agggccttct ataaatagat tgaatatggg attagaaata agaaatcctc
    38161 ttttagatga aataaaaagc aagtattcat atgcctatga tggagttgaa aagatttcta
    38221 gaattataaa agataaacta aatataaatt caatacctga atcagaaata ggatatattg
    38281 caatgcactt tgcatcagcc atagaaaaaa atcttatgat gaatactaat ataaatattg
    38341 ttgtggcatg tcccactgga ataggtactt caagattctt atcaactaag attgaaaata
    38401 aatttcctaa tttaaatata cttgaaacca tatcagctat aaacatagat gaagagtatt
    38461 taaaagaaaa agatgttgat ttaatagtgt ctacagttga gttaaataca agtttaaatt
    38521 atatatgtgt aggtccattt atgagtttag atgatgaaca gataatcaag gaaaaaataa
    38581 aatctatagc tcaaaataaa ttaatcaatt taaatgcgaa aaatgatact aaaagtaaga
    38641 ataaagtata tgaacagata acagaaagta tgaatatagg aaaagatatt cttcaatttt
    38701 tagaggaaat tagatttgaa aaatttgaaa gtaaagattt aagtgagctt attgaagact
    38761 catcaaaaat atttgcaaaa tctagtgaag atataatctc tataaaagaa tcgttaaaag
    38821 aaagattaaa aatctcaatt ccatatatag aagaatcaaa aattctattg ttacattgta
    38881 tgagtgaaag aatagatatt atgaagttat caataataaa actagagaat agaatcgtgc
    38941 tagattcaaa tgaagaaatc gataatgtag tttttatgtt acttcctaaa aattcaccaa
    39001 gttatcaaag acaaataatg agtgaaataa gtggttcatt aatagacaat ataattttta
    39061 ctaataagat aaataaattc tctatagaag agatgacatt agaggtaaaa gatatagttt
    39121 ttaattttta tacaaacaga ttaaaagcat ttatagataa ataaaattaa tattaaaaag
    39181 gaaggttgat actatgagta aagtattgaa tgagaataat atatttttag ggttagatag
    39241 tgtttcaaag gaagaagcta taactttagc aggaagaaaa ttagttgaaa atggatatgt
    39301 aaaagaagaa tatataccag caatgttaga aagagaaaaa gtaatgacta catatatggg
    39361 aatgggagtt gctattccac atggtgtaaa tgaagcaaaa aaagaaatat tatcttctgg
    39421 aatagttata ttacaattcc ctaatggtat agattttgat ggagaaaaag catatttatt
    39481 aataggaata gctggtgttg gagatgaaca tttagaaata ctatctaata tagcagtagt
    39541 tttagatgat gacttaacag aaagactaaa aaattcaaat gacaaacaag cttttatgga
    39601 agcttttgcc aactaatctt aggagggatt taaaatgaaa aaggcgattc agtttggagc
    39661 aggaaatatt ggaagaggtt ttattggaag cttgttagtt aagtcgggtt atcatgtagt
    39721 atttgctgat gtaaatgagg agatattaaa ctcaataaac aaagataaaa agtatactat
    39781 acacataaga gatgtagaat gtatagatga agtaattgat aatataagtg cggtttcatc
    39841 tataaaagaa gaaataatag atgagattgt acaggctgaa ataataacta cagcagttgg
    39901 acctttagtt ttgactaaaa tagcctctac aattgcaaaa ggtataaaag ctagaaaaga
    39961 aaagggatta acaagtaatc taaatataat agcatgtgaa aatgcaatat acgcaagttc
    40021 ttctttaaaa gaagaggtac ttaagtattt aaataaggaa gaagtagaat atttagagat
    40081 gtatgttggt tttccaaact gttcagttga tagaatagtt cctcctggta aaaacgaaaa
    40141 tcctcttgat gtaacagttg aaaattttta tgagtggaat gttgaaaaac aaggatttaa
    40201 aggggaaata ccaactatag ttggaatgaa tttagctgat aaccttatgg cttatataga
    40261 acgtaaattg tttacactga atacaggtca tgctataaca gcttatatag gatatttaaa
    40321 aggatataag actatagaag agagtataaa agataaattt atctgtgata tagtcaaaag
    40381 tgcaatggta gaaagtggag aaggattgat taaaaaatac aattttgact cagaagtgca
    40441 ctataaatat attgataaaa ttttaaatag atttaaaaat ccatatctta atgatgatgt
    40501 attaagagtc ggaagggaac cattaagaaa actaagtgat aaagatagat tgattaaacc
    40561 tttaatgaca gcaaaatcat atggattatc agttgacaat ttgattcttg gaataggtgc
    40621 agcgcttcat tataataata gtgaagatac tcaaagtgta gaattacaag agttgataaa
    40681 gtctattggg gtaaaaaaag ccgttgctaa aatagctaat ataagcaatg acgaagaaat
    40741 tttaaataat atcgaaaaaa gttatatatt tatgaaaaat ttataaattt acttgaaaaa
    40801 aagtagttct gataaagtaa ctataatata ttattctaca cagtttgaat tatttgttga
    40861 ataatagaga attataatat ataattaaaa ggaataaatt aatatattta cctgtatatg
    40921 tttgataata tggttcaaat gtttctacta agctaccatt aatagcttga ctacaggagt
    40981 gaagaagata tagtttatac ttattttaaa ttatatatta agttaattac tttgaatttt
    41041 aagctcctgt ctatgatata gacaggagct tttttagtat tttaatataa aatacttaca
    41101 agaatagata gcaaaattag aacaaatata atttttttat taatataatt ttagaaaggg
    41161 ctaggtggaa gttcaatgaa ggctttacaa gaaaagatat tgagagaagg cagtgtttca
    41221 ggaaatgata tactaaaagt tgatagtttt ttaaaccatc aaattgatgt agctttttta
    41281 aatgaaatag gaagagaatt taaagagaga tttaaaggag aaaaggtgga taagatattt
    41341 acaatagagg cttcaggaat agctatagca tcaattgttt cacagtattt tgataatgca
    41401 cctgtagtat ttgcaaaaaa atcagaatct aaaaatttgg ataaagatgt atatgaaact
    41461 aatgtatatt catttactaa ggcaagagag tattcagtta aagtttctaa aaagtacata
    41521 aacaaaggcg aaaatatatt gatagtggat gattttttgg caaatggaag agctgctctt
    41581 ggacttaaag atttaattga gcaagcagaa gctaacttag ttggagtagg aattgtcatt
    41641 gaaaaaggat ttcaagctgg aggagcactt ttaaaggcta atgatgtaag attagagtct
    41701 ttggcagtag ttgaatctat agataatgga actgtaaaat ttaggtaatt tatgatatta
    41761 tataattgtg tttagcacat attttaacta tgtaattatg gaggattttt tatgaggttt
    41821 tttatagaca cagccaatat tgaagaaata aaagaagcaa atgatttagg tgtaatatgt
    41881 ggtgtaacta ctaatccgtc tctaatagct aaagaaggta gagattttat agaggtagtt
    41941 aaagaaataa gtgaaatagt agatgggcca ataagcgcag aagtaataag tttagaacat
    42001 aaaggtatga tagaggaagc agaaaaatta tctaagatac ataaaaatat agttataaaa
    42061 atacctatga cagcagaagg tctaaaagcg gtgaaagtac tatcaagtaa aggtataaag
    42121 actaatgtaa cgcttatatt ttctgctgga caagctcttt tagctgctag agctggagct
    42181 acatatgtaa gtccttttgt tggtagattg gatgatatat cacaaaatgg tcttgattta
    42241 attgaagaaa tcgttgatat atttagtgta aatagtattg aggctcaaat aatagttgct
    42301 agtgttagaa atccaataca tgttttacaa gctgctagaa tgggagcaga tatagcaaca
    42361 gttcctctta aagttataaa ccaaatgatt aagcatcctt tgacagacaa aggaatagat
    42421 agctttatga aggattggga aggtgctttt ttaaaattat aattataaac tacgctttat
    42481 aagtatatta aagaggttat tatggaaatt ctaagtaata aggctaggct attttgccta
    42541 gtcttatttt ggtgtataat atattgaaac atattattga aatagattaa ttttttaagt
    42601 gaggaggcga aaaatggata aaatattaag agagatacaa agagaagata aaaaaaatcc
    42661 atatactgac caagaacttg ctgaaatgtt aaatgtagct aggtctgaag tgatatcagt
    42721 taggaaaaaa aataatattt tagattcgag agaaagaaga aaaaaaatat taataaaaga
    42781 tatatcaaaa attgtaagtg aaaatcctca aatgtctgaa agaaaaataa ctgaaatatt
    42841 aatagaaaat ggatataata tatcgagaag tgcagtttca aaattattaa aagaggaaaa
    42901 tttaaatcag tcaaagattg ggattaagga taaagaccca gcatcatcag gaaagtatgt
    42961 gaaggtgagt aaagttgtag aagaagatgg atttgaagaa ttgataggta taaagggaag
    43021 tttgaaagaa aaggtaaatc tagctaagtc agcaataatg tatcctccta atggccttca
    43081 tactataata tatggagaaa caggagtagg taaaagtgaa ttagctacat gtatgtataa
    43141 atatgctata aaaaacaaca ttaaagaaga gaacagccca tttatagtgt ttaactgtgc
    43201 agactatgca gaaaatccta atctattgat agctcaactc tttggggtag taaaaggtgc
    43261 atatacagga gcagatgcaa atagagaagg tcttgtagaa caagctaata atggaatatt
    43321 gtttttagat gaaattcata gattgcctgc tgctgggcaa gaaatcttat tttcattaat
    43381 agatagagga gaatttagaa ggttaggaga aagtagttct aatagaaagg caaatgttct
    43441 cataataagt gctacaacag aaaatccaga ttctaattta cttcaaacat ttagaagacg
    43501 tataccaatg gtaataaatt tacctaatat gagtgaaaga ccaaaatctg aaagatatga
    43561 aataataata aagttttttg aaagagaagc aaagcgagta aacaagaatt ttataataac
    43621 taaagaagtt atgtgtgcac ttatgaatta taagtgtact ggaaatatag gtcagttaaa
    43681 gagtgatata caagtaactt gtgctagagc ttttagtaaa tcgatatttt ctagcgataa
    43741 ggtaattata gatttagata gtttaaggga ttatataaaa agtggatatt atgattgtaa
    43801 ttgtaaaaat gaaaagtatt ctgagttttc agttgaggat atatatatag atattagtga
    43861 attggtgagt ggaaaaaata gaattttatc tgataatgag ataagcgaga tatataatta
    43921 tgcagaaaaa gagcttaagg ttttggaaag taagtgcttt tcagaagaag agttaaaaaa
    43981 tgcatttata gaaaagttag ataagaagtt taatgctatt aaaaacaata aaaatttatc
    44041 tgatagaaga agtcgaatag actggggagg acaattaaaa gagtctacac tggagataat
    44101 ggataaggta attgtattta ttaaggagca gtttaagcat gtaaatcaag gtctgtactt
    44161 ggctctagca attcatattg agcatgctat aggtaggata aaagatggaa aaactataat
    44221 aaatccgagt ttagataaaa taaaagcatc aatgccaatg gaatatgagt tgtcaagata
    44281 tataatgggt atagtagaag atttgacaca agtaacattt ccagaagatg agcttggata
    44341 tttggcttat tatataaata aattttgtta taatgaggaa agtataaaag ataaagttaa
    44401 agtagtaata gttacgcatg gtaaagttgg aattgaaatg tctaaagttg taaatcatat
    44461 tttaggtata gaatgtacac taggtataga aatagcactt acagattcac catcagaggg
    44521 gatagagcat gtattagaag agcttcaaaa gatagaagct agaaaaggta ttctagttct
    44581 aattgatatg ggttctttgg taattcttgg tgatgaggtt gaaaaaaggc ttggaattag
    44641 atgtaaaact gtaaatagag tagatacatt attggcaatg gaagcaggaa aacttgcaac
    44701 cattgaagga aaaagtttag atggtataat agctgattta aagaaaaata agaattatgc
    44761 tatgataaat acaaataaat ttagttacag aaaaaacgag tatggaaaga aaaatgtaat
    44821 cattacttta tgtttgagtg gtgtaggtac agctttaaat ttaaaagagc atatagaaaa
    44881 acaaattaag gaatatggca ctttaattga agtaaagcca gttgcttttt taaataataa
    44941 tttagaagaa gagttaaatg atattgaagc tgaatataat attattgcta tctgtggaac
    45001 tattgatata gattataaaa acgtgccttt tatttcttat aatgaggtac ttggtaaaaa
    45061 tggtattaat aaagtattag agcatctaaa tagtaaacaa ccagctttaa atattgaaaa
    45121 ccagttgaat aatttaatac atgaagattt gattttatac aattttgaag gaatttcaaa
    45181 ggagtatata attgatactc ttgtttcaaa acttgaagaa ggtggatatg ttgattcaaa
    45241 gtatatatta agtgtatata aaagagaagc aatgggaagt gttgtaatgg cctctaaggt
    45301 agccgtgcca catggacttc cagaaaacgt tataaagcct gcaatagcaa tcgcaaggtt
    45361 gaataaacct atagtatggg acaataaatt tatggtggat ttggtggtac tactggcact
    45421 taaagaaaat aataagaaag aaatacgaag cttattttca aagattaatg accagcatac
    45481 tttagaagtt ttattaaata ctgaagataa aaatgaaata aaagaacttt taagctaatt
    45541 attagtaccg agaagaaaga caaaaaaatt tgctttagta taaaatttaa aattactcaa
    45601 ttgctaagta gttaattact ctatataagg ctagttctat gaaatttatt tatatgattt
    45661 tatagaatta gcttttttct tggtaaataa aatatatgaa tttatttatg taaaaagtaa
    45721 attttattgg acaattctat gaaaattttt
//
LOCUS       DAMJYN010000028        45616 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.028, whole genome shotgun sequence.
ACCESSION   DAMJYN010000028 DAMJYN010000000
VERSION     DAMJYN010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 45616)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45616)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45616
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.028"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            172..831
                     /gene="cprR"
                     /locus_tag="PC466_001615"
     CDS             172..831
                     /gene="cprR"
                     /locus_tag="PC466_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CprR"
                     /protein_id="HDF2769003.1"
                     /translation="MSKILVVDDELDMLKLIENVLKRDGHEVKVISDVEKAMNMDFNY
                     FNLIILDVMMPKMDGFEVCKTIRNKVDCPILFLTAKNMESDIMYGLGIGADDYITKPF
                     GVGELRARITAHLRRESREKKNLLTISNVQFNFLGKEVSIDGKKINFTKSEYLICEFL
                     AKNKGQVFSKERIYESVYGFDGESDISTITEHIKNIRSKLKQYDIYTIETVWGIGYKW
                     V"
     gene            1042..2100
                     /locus_tag="PC466_001616"
     CDS             1042..2100
                     /locus_tag="PC466_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HDF2769004.1"
                     /translation="MDRLKNIRKSLLQYTFLFLLIGITIYLVFKTLDIKMLSNVMVMV
                     DKKFLFIGALAIMCHIMLEGVVMKIIIESTHKVNIRFIGFKLAIMGFYYNLITPFASG
                     SQPVQIYVLKKCKMPLSKASAVVTNKSIIFQIVVTFYCTILVLMNFAMLEKQMKMIMP
                     LVFLGIAINSFVLIMIILVILNPKKIKYFMRITIKHLSKIKFLKFLDNKIESIESFID
                     DYSKAINFFAKNKKVLISTIIVTFIQLSAYFSVSFWIYKAFNLQGYSYIYILTLQAFL
                     YMAISPIPTPGNVGANELAFFTIFKSVFPQPLMGYAVFLYGGFMYYLILIGSGIFTVI
                     THYRMKNRIGRNIVLSEN"
     gene            2351..4495
                     /gene="fdhF"
                     /locus_tag="PC466_001617"
     CDS             2351..4495
                     /gene="fdhF"
                     /locus_tag="PC466_001617"
                     /EC_number="1.17.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:2765..2767,aa:Sec)
                     /transl_table=11
                     /product="formate dehydrogenase subunit alpha"
                     /protein_id="HDF2769005.1"
                     /translation="MEKKILTVCPYCGAGCQLYLVVKDNKILRAEPANGRTNQESLCL
                     KGRYGWDFLNDPKILTPRLKKPMIRKQGVLEEVEWDEAINYTASRLNEIKEKYGPDSI
                     MGTGSARGPGNEANYIMQKFMRATIGTNNVDHCARVUHAPSVAGLAYSLGSGAMSNSI
                     PEIENADVLFIFGYNGADSHPIVANRIVKAKKNGAKLIVTDPRVTESARIADIHLPIK
                     GGTNMVLVNAFGNVLIEEGLYNKEFVQNHTQGFDEYKEIVKPYTAKYAEKITGIPEEL
                     IRKAMREYAKGKKAMILYGMGVCQFGQAVDVVKGLASIALLTGNFGRESVGIGPVRGQ
                     NNVQGACDMGALPNVYPGYQNVTDDKIREKFEKTWGVKLSPNNGYSLTQVPDLVLKEK
                     KLKAYYIFGEDPVQSDPDASEVREALDELEFVIVQDIFMNKTALHADVILPATSWGEH
                     EGVYTCADRGFQLMRKAIEPQGDVKPDWQIISEISTAMGYPMNYKNTKEIWDELRQLC
                     PSFLGATYEKIETQGCVQWPCKSESMEDKGTMYLYEGQKFSTPNGKGNLFAAEWRPPM
                     EVEDDEYPFSLCTVREVGHYSVRTMTGNCRTLSSLEDEPGRVQINSNDAEKLGIEDDE
                     LVRISSRRGSVITRATVTDRVKEGATYMTYQWWVGACNELTIANLDPISKTPEYKYCA
                     VKLEKLEDQELAEKCVREEYQSLKDKMTATNI"
     gene            4544..5377
                     /gene="fdhD"
                     /locus_tag="PC466_001618"
     CDS             4544..5377
                     /gene="fdhD"
                     /locus_tag="PC466_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase accessory
                     sulfurtransferase FdhD"
                     /protein_id="HDF2769006.1"
                     /translation="MNNIYSKTKLQENSKDKVFENSYSLVDYKYLNSFNVEVSKINEH
                     EVSIDNEEIIAEYPLSFILNDKYVNTFLCTPYNLEELIVGFLKTKGYIENKKSLLKFE
                     INESERFAKVTIQEKQKNQDEQIIFLNSLDYITCASVKSNIKINYDTIYSIMDRNLNS
                     SELFKNTGGVHSVSVFNFDKKIVTCEDVARHNAMDKAIGFCVLNDITLKDKIVAVSGR
                     ISLEMILKAAMTQIPIVVSKSAPTNLSIELSKKLNITLIGFVRGRRMNIYANPQRVIK
                     K"
     gene            5388..5561
                     /locus_tag="PC466_001619"
     CDS             5388..5561
                     /locus_tag="PC466_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769007.1"
                     /translation="MCTKKEEQKCSKCEICGVLIDDTDKVYNNTYNLCKKCKRNISTE
                     KIVKYINIYDESK"
     gene            5619..6170
                     /locus_tag="PC466_001620"
     CDS             5619..6170
                     /locus_tag="PC466_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HDF2769008.1"
                     /translation="MKNKIGSFVIADPNKCTGCRACEVACFTMHNQHNNVGYTVGTVD
                     IPVIPRLYLVKGDNFCMPIQCRHCEDAPCLNSCPQKAIVKENNIMSVNEEKCIGCKTC
                     LLACPFGAIDLLPQYEDGKEVEQVILDENKKIAYKCDLCKDNEKIACISACPQEALKL
                     VTPIDDKKAKNRQAALSLLLTNK"
     gene            6195..7571
                     /locus_tag="PC466_001621"
     CDS             6195..7571
                     /locus_tag="PC466_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron hydrogenase small subunit"
                     /protein_id="HDF2769009.1"
                     /translation="MIINIDKDLCTGCRECSKVCPVNAIEGEEGKPQEINLDRCVMCG
                     QCVQTCKSYASVIDEGFEFLQEKKQEREIPESINEPIFAAYNVCDIDKVKKALSDPNV
                     FTMVQCAPAVRVALGEDFGYYLGYLGAGKMAAALRALNFDRVYDTNFAADLTIMEEGS
                     ELIKRVTEGGTLPMFTSCCPAWVKFMEKNYPKLTNHLSSCKSPQQMGGAIFKTYGAEI
                     NNVDASKIFSVSIMPCTCKKYECDREEMDSSGYRDVDVVLTTRELAYLIKDMGIDFKN
                     LREEKFDSPLGSYSGAGTIFGVTGGVMEAAIRTGYELITGESIPDVEVKQVRGENGFR
                     KSTIKIGDLDLRVGVVSGLKNVIPVLEDLEKGKLDVDFIEVMTCPVGCVSGGGQPKIL
                     LEEYKELAYENRTKATYVHDEHLAIRKSHENPDIKKLYDEYLVEPLGEKSHHLLHTTY
                     CIGKEVAK"
     gene            7571..8086
                     /locus_tag="PC466_001622"
     CDS             7571..8086
                     /locus_tag="PC466_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HDF2769010.1"
                     /translation="MNYFVIADPDKCIGCRTCMIGCVVAHSDEDIFYQNPDEINFNPK
                     LSVIKTKEVSAPIQCRHCEDAPCAKACPNGGIVRVGNTIKINEENCIGCKTCMLACPI
                     GAIDIVTLKDVDEGKLCFRERMTANKCDFCIESPEGPACVNVCPTKAFTIVKDEDIDS
                     KVKNKRKLAIL"
     gene            complement(8164..9447)
                     /locus_tag="PC466_001623"
     CDS             complement(8164..9447)
                     /locus_tag="PC466_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugated bile salt MFS transporter"
                     /protein_id="HDF2769011.1"
                     /translation="MNTLLNNKFSIKNFSNAWVIVLGCMLIQAVPFSIVASIQPQFIS
                     YVVEGEGFSLASFSLIFTIGTIASAIASPFIGVLFSKVNIKILYLLGCIISSIAFATF
                     SICTELWQFYTVSCIVQIGATIISAIGIPVLISAWFDEESKGKALGFAFAGGSIGSIF
                     LQPLAVRLLATQGYSHSYLIFGIIALIVGIPVILFILRMPKDINEKVKSKGKKEKASD
                     TISPSVWGYTLKEAKKIKYFWIMTIGFIFVGIYVSSLSVQYPTYLRNYLNPILIGTVG
                     STFALFALIGNLFGGLLFDKFGQTKPLIISFVLVLIATLSLLLVDKSSTFAFVFAILK
                     GLSVFAYMIGPAYLTGSFFGQKEFGSIYGIVQLIFAVGFALGSTLFGLLVDNFGYRFS
                     WSIIILSVIIAYTLLIITSIGMKKLNKERLDKLMQ"
     gene            9635..10057
                     /locus_tag="PC466_001624"
     CDS             9635..10057
                     /locus_tag="PC466_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3783 domain-containing protein"
                     /protein_id="HDF2769012.1"
                     /translation="MSFEKINNNNLDKIHNRKCIMLVNFNKKELSLIKNVSNFAGIRD
                     HIILSEKNGENIIRDILDGNISSECENGIKSKSVIFNNTPSTQVNAFLEGLKKVRINR
                     PFTAMVTETSIDWTLNNLIENLVQERNAMSLGKTIEHK"
     gene            10159..11097
                     /locus_tag="PC466_001625"
     CDS             10159..11097
                     /locus_tag="PC466_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HDF2769013.1"
                     /translation="MKVLFTINYGKEKFDKIRELGYDVIHYSEDSIENNEDVNTADVL
                     VTYNPFERLDISKMKNLQYIQTTSVGIDQLPKEEVLKRNIKIANNRGGYSVPIGESIV
                     LYILEIYKNSAKFFKQQQNKEWKMDFSVSELYGQRVGFLGTGTISSEAAKRLKAFGVE
                     IWGVNTDGSSKKYFDKCFATEDMNIVFEECDIVVVAMPSTKSTDGIVNKDMFKLMKDG
                     SVFINVGRGNTVNQKDLEECVEKFRGVALDVFESEPLNKDNKLWECENVIVTPHNSWV
                     SDKNKERTFNMVYNNLKHYIMENKPVDNVVDISRGY"
     gene            11283..13307
                     /gene="ligA"
                     /locus_tag="PC466_001626"
     CDS             11283..13307
                     /gene="ligA"
                     /locus_tag="PC466_001626"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HDF2769014.1"
                     /translation="MSVKDEINKLIETINYHNERYYNQDSPEISDYEYDKLMKELISL
                     EEEHPELKRIDSPTNRVGGKPLDKFNQIVHKTPMLSLSNAFSEQDLRDFDKRVQEYVG
                     ENVEYVVEFKIDGLSVGLTYNNGEFEKGATRGDGVVGEDISQNLMTVKSIPLKINDKK
                     ELIVRGEVYISKDNFRKVNEQQEEQEQPLFANPRNLAAGSLRQLDPKLTAKRPLDIFV
                     FNMENIEEYDLESHSESLEYLEKLGFSVSQSYKVCKSIDEVIEHIEYWTDNRGNLDYE
                     IDGMVIKVNNIKQRDEMGYTAKSPRWAIAYKFPAEKKKTKIVDIIVEVGRTGTITPSA
                     ILEPVRLAGTTVSRATLHNEDYIREKDIKINDTVLVQKAGDIIPQVLEVIKEERTGDE
                     IDFKMPEKCPVCSEPTIRLEGEAAVKCINMSCPAQIRRGIIHFVSRDAMNIDGLGESI
                     ITLLLNEKIIQDVSDLYYIKKEDVVDLERMGEKSADNLINSIEKSKENDLWRLINGLG
                     IKFIGVKAAKILAYNFKDLDEVISATSEQLEELEEFGSIMANSVVEFFKEDKNMNVIN
                     KLKNVGVNTKSLDNTGEKVEKIFEGMKIVLTGTLPTLKRNDAKDMIEKRGGKATSSVS
                     KSTTFVLAGEEAGSKLTKANDLGIKVIDEERFLELLKLSSKDEVKAVLES"
     gene            13467..14816
                     /gene="rph"
                     /locus_tag="PC466_001627"
     CDS             13467..14816
                     /gene="rph"
                     /locus_tag="PC466_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HDF2769015.1"
                     /translation="MTRSYDRSNEQIRPVKITRDYTKYAEGSVLIEMGETKVICTASV
                     EEKVPPFLRNSGTGWINAEYSMLPRATQQRKIRDASRGKIDGRTQEIQRLIGRAIRSV
                     VDLNKLGERTIWVDCDVIQADGGTRTASITGAFVAVAEAIYKLYKAKTIKEMPITNFV
                     SAISVGIVNGIHMLDLCYEEDSKAQVDMNIIMTDKCEFVEVQGTGEEKPFSRADLNLL
                     LELGEKGNKELIRLQREALGEIADEILGMDYGNEVVIATNNAHKLEEIGEILKDFEYK
                     VYSLKDVDLAGIEIVEDGKTFEHNALIKARAIAKKTKLIAISDDSGLEVDALGKKPGV
                     YSARYAGEHATDEENRKKLLKAMQNVPMSKRNARFVSAIAVVFPDGKEFVVRGICEGM
                     IGFEEKGKNGFGYDSLFIVKGYDKTFGEIPSVIKNSISHRANALKLMKQEFIKRVVK"
     gene            14816..15286
                     /locus_tag="PC466_001628"
     CDS             14816..15286
                     /locus_tag="PC466_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HDF2769016.1"
                     /translation="MKIGIVSDTHMMIKNMEKTIPYLKECDLIIHAGDNFTDSRYIHS
                     MTNVGIIAVKGNCDFDAVEEEVVFEVANKTIFLCHGDKYGVKYGTNMLEKKATEVDAD
                     IVIFGHTHTPFREIKDGVLYINPGSTSLPRGVSYKSFVIMDIEEDDIKIEEIRI"
     gene            15480..16766
                     /locus_tag="PC466_001629"
     CDS             15480..16766
                     /locus_tag="PC466_001629"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HDF2769017.1"
                     /translation="MKAELIKKEGNKVTLKITVDNNKFEAAVNKAYNKSRNKYNIPGF
                     RKGKAPRIVIETQYGKGIFYNDAIEILFPEVYPEAIKELDIDPIDNPDLDIEEISKDN
                     GLVMVLNVEVKPEFELGNYKGIEIAKVENTVSDENVDAKLQEMVEKNARLVSVEDKAL
                     EDGDTAIIDFEGFENGVAFDGGKGENYNLVIGSNTFIPGFEEQLVGKKAGEEVEVNVT
                     FPEEYHSQDLAGKPVVFNVKINDVKVKELSALDDEFAKDTSEFDSLDELKADVRAKLE
                     EEAKNRADAETRNSVVEKVAENTEIEIPEVMIQHQIDNMLNELNYQLQYQGFGLQQLL
                     EMTGRTMEELREERKEDAKKLVKSSLVLEAITKAEGIEATEEEFKAELEKMASAYNME
                     VEKIEASLRDADKEDIKGQIKIRKTIDLLVDNATIA"
     gene            16915..17499
                     /gene="clpP"
                     /locus_tag="PC466_001630"
     CDS             16915..17499
                     /gene="clpP"
                     /locus_tag="PC466_001630"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HDF2769018.1"
                     /translation="MALVPVVVEQTGRGERSYDIFSRLLKDRIIFLGDQVNDATAGLI
                     VAQLLFLEAEDPDKDIHLYINSPGGSITSGMAIYDTMQYIKPDVSTICIGMAASMGAF
                     LLAAGAKGKRLALPNSEIMIHQPLGGAQGQATDIEIHAKRILKIKETLNEILSERTGQ
                     PLEKIKMDTERDNFMSALEAKEYGLIDEVFTKRP"
     gene            17518..18768
                     /gene="clpX"
                     /locus_tag="PC466_001631"
     CDS             17518..18768
                     /gene="clpX"
                     /locus_tag="PC466_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HDF2769019.1"
                     /translation="MSKYEEKRQLKCSFCGKNQDQVRRLIAGPNVYICDECVELCDEI
                     IQEEIEDTIDEDTTSLPKPKEMMEILNDYVIGQEKAKKALSVAVYNHYKRIYSKKSSS
                     KDIEIQKSNILLLGPTGSGKTLLAQTLARTLNVPFAMADATSLTEAGYVGEDVENILL
                     KLIQAADFDIEKAERGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKILEGTVAN
                     VPPQGGRKHPHQEFLKIDTTNVLFILGGAFDGLEKIIQKRGGDKTLGFGAKIESKKEL
                     DLGKLYEKVLPEDLLKYGIIPEFIGRIPVLATLELLDEDALMQILQEPKNALVKQYKK
                     LLELDDVELEFEEGALRAIAKKAIERNTGARGLRSIVESVMMETMFEVPSRDNIKKVI
                     VTEKSVNEDSVNPIIVLKDQEESA"
     gene            complement(18839..19366)
                     /locus_tag="PC466_001632"
     CDS             complement(18839..19366)
                     /locus_tag="PC466_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HDF2769020.1"
                     /translation="MSEIILLFLIFLKIGAFSFGGGYAMLPFIQQEFISKYHFITNQE
                     FLDLLAISQSTPGPVAINSATFVGFKTAGFFGSLAATIGVTIFALIGLTIISKLFSKF
                     KNNKKVENLLTVLRPITLGFILSAAFSSAKEVNWDLYGIIAFIASFYLLYKGKIGSIA
                     IVFVFGILGILLTFL"
     gene            complement(19354..19866)
                     /locus_tag="PC466_001633"
     CDS             complement(19354..19866)
                     /locus_tag="PC466_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HDF2769021.1"
                     /translation="MLKLFLTFLKIGAFTFGGGYAMVPLIQDELVNKQKLLEQEEFID
                     YLSIAQSYPGVLAVNISVLLGYKLYGIPGVLICTLGSALPSFCIVLVLSYLYFKNSSS
                     KILDGFFKGVAPVVIALILYSFTSMFKKLPKSKTNILLLIIAVLSVGVFNISPIYLII
                     GGGVYSLCQK"
     gene            20046..22409
                     /gene="lon"
                     /locus_tag="PC466_001634"
     CDS             20046..22409
                     /gene="lon"
                     /locus_tag="PC466_001634"
                     /EC_number="3.4.21.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase La"
                     /protein_id="HDF2769022.1"
                     /translation="MEQNYTKIDHELPLIPLRGLAIFPYMILNFDIGREISLKALDQA
                     MMDEELIFLTSQKEAEVDEPGEEDFYHVGTICKVKQMIKLPGDTVRVLVEGVSRGRVK
                     KIEQEDGYFRAVIEEIVFNSDNLDSETEVEIEAFVRNVFDAFEEYINIGNRVSPEILI
                     SLADIEDVDRFIDTIAANIYLKSSQKQEILEEFDIRKRLELIYSILLEEIDILKIEKK
                     ITLRVKKQMNKVQKEYYLREQLKAIQKELGEEEDINSEADEYREKLKKIKAPKTTKEK
                     IEKEIDKFSKISSMSPDVSVSRNYLDTIFSLPWNKETKDKLDITKAKDILDEDHYGLE
                     KVKERILEYLAIRTLAKSLKGPIICLVGPPGTGKTSIVKSIARALNRKFVRISLGGVR
                     DEAEIRGHRRTYVGSIPGRIINGVKEAQTKNPVFLFDEIDKMAADYKGDPASAMLEVL
                     DPEQNKDFVDHYLEIPFDLSKILFVTTANSLGNIPRPLLDRMEVIEVSGYIEEEKLNI
                     ARKYLLPKQIKEHALKENFIKIDDETLRSIINHYTREAGVRTLERTIGKICRKVAKKY
                     VEDPTLEEVVINKSDLETYLGKDMFKYQLAEVNPQIGLVNGLAWTAVGGVTLEVEVNV
                     LKGKGEIVLTGKLGDVMKESAKTGISYIRSIVDKFDIDPEFYKTNDIHIHIPEGAVPK
                     DGPSAGITMALAVISALTKRPVPGNIAMTGEITLRGRVLAVGGVKEKLLAAHRAGITK
                     VLIPKECEADLDEIPENVKEKMEFVLVEHMDEVLEQALLKSGENNEN"
     gene            22399..23010
                     /locus_tag="PC466_001635"
     CDS             22399..23010
                     /locus_tag="PC466_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HDF2769023.1"
                     /translation="MKIRSSEITMSAVNKSQYPAEGIPEIALAGRSNVGKSSIINTLL
                     NRRNFARTSQTPGKTRTINFYLINNEFYFVDLPGYGYAKIAKSEKEKWGGIMERYLES
                     RQELCSIFLLVDIRHEPTADDKLMYEWIKHFGYNCVVIATKADKISRGQYQKHISIIR
                     KKLQMESSEKVIPVSSLKKTGVEELWEEIVNQYNQHGYEITVD"
     gene            complement(23275..24645)
                     /locus_tag="PC466_001636"
     CDS             complement(23275..24645)
                     /locus_tag="PC466_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2769024.1"
                     /translation="MKQKWIVLIIICIGVFMSTLDGSILNIANPTIAADFKINMSQIQ
                     WVVTAYMLVVTATMLFFGKLGDKVGSNRLYALGFFIFTIGSFLCSMSNNLSTLISSRI
                     FQAVGASILMATGLGIVSNAFPANEKGKAIGITGAVVGIGNMSGPVIGGIILEHFGWP
                     SIFIINIPIGIIAVFLGIKFLPKPVLDEQNKSFDISGLLLFASCTTLILLAMNEKGNT
                     RLYLGITALIIFLLLALREVKFEQSFIDLPLFKNRNFTVGNIIGVACYFPQMAVSFLL
                     PFYLEQLKNLSPMMAGYVMTVHPLIMVLIAPIAGSLSDKHGAKNILTASFSFMTISLV
                     GMALLKADSPLYLLIVCLVIFGLGLGAFSSPNNSSILADVPPQKQGYGGSFLATIRNL
                     SFALGTAFFSSFFAQSLTYNQKFKSHTSAYVIASNQSYWIAASVCFIGLILTVFFMRK
                     TDKSIS"
     regulatory      complement(24820..24935)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            25223..26302
                     /locus_tag="PC466_001637"
     CDS             25223..26302
                     /locus_tag="PC466_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF2769025.1"
                     /translation="MEGKVKKAFPGGNTSQGSYSFFDYIIPENVKRVFCLKGGPGVGK
                     SSLMKKIYKEFLHRGYDIDLYHCPSDPSSLDGLVIKKLGVVLMDATAPHTMDPKLPGA
                     LDEIINLGDYWNTEELEKNKQEISVYDKDISNSFKRAFKFLKSAEPIFRDIEEKYSDC
                     MDYGKVNLVTEEFIKRLFDGVKSTGNLKREKHLFGSAITPVGCLDYTENILKDVKKVY
                     YLDGEIGTGKTTLLNKVYKKATEKGLNVEVYHYPLIPEKIETVLLTDLDIGITISTTF
                     KEEDTIDLNQFLNREKLLKYEEDIKFDEKVLDDLICWAVLNLKRAKSKHDIIESYYSP
                     NMRFDEVGKLRDKLIKRILKYEENL"
     gene            26694..27374
                     /locus_tag="PC466_001638"
     CDS             26694..27374
                     /locus_tag="PC466_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF881 domain-containing protein"
                     /protein_id="HDF2769026.1"
                     /translation="MKKQYVFIILASTILGILVGTIFRDYSNEETVYTSKDKSIRKEI
                     KMTRKSIKELTKEKDKLDKEINSMKQNQKNSEEISEIETLRDSLSYSDVKGSGIILSI
                     DAIDEKTGNIANSIDYNKILVKVINELKVNGGKYIEINGQRINQYSEVVLAGSHININ
                     GVPVAQPYEIKCIGDKEKLSNYVDKGSKYLDSIQTNYPMKISIKTEENISMKKMNIPN
                     KLKYIKGD"
     gene            27367..28746
                     /locus_tag="PC466_001639"
     CDS             27367..28746
                     /locus_tag="PC466_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HDF2769027.1"
                     /translation="MINIILEESSLPMLIPEKLAKKYNVFPVEFQDDNLVVEIEDEDI
                     YALQDLRLATGKEIILKKEKKELISEKIEKYYNSFELDEDYAKKLFENLLEKAIKENA
                     SDIHIEPFKEHLIVRMRVDGELKEVSKFLVDVYPSLSTVIKLKASMDITEKRLPQDGR
                     VDIKLGGNLIDIRVSSIPTVYGEKIVLRILNRDTFLKDKLELGFSEEAIKSINRIINK
                     RAGVLLVTGPTGSGKTTTVYSLLNDLKGINKNIMTIENPVEYKMDGISQIQVNSKVGL
                     SFDVGLRAILRQDPDIIMVGEIRDAETAKIAVRAAITGHLVISTLHTNDAVSSIARLL
                     EMQIPPYLLNASLIGVISQKLVRKVCNHCSHEIMIKDNFSGDVNTKVAVGCEKCNDKG
                     YFGRTAIYEILEINDDIKTCIRNMEDSSTIKDVAQNNGMITFEDSCKRLINEKITTLE
                     ECLVVNEMI"
     gene            28917..30002
                     /locus_tag="PC466_001640"
     CDS             28917..30002
                     /locus_tag="PC466_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HDF2769028.1"
                     /translation="MRLSKNIFYNLEKFYLVLNRISDKEIRVICKEIGILLESGCEIT
                     KIFEIIESQSSKKVKNLLSIVSNHIQKGNSIAESFQITGIFSKFFISMIKAGETSGNL
                     DIIMSDLSNYYDKEYKLKMKIITISIYPIILIILSILSMLFIFVFVIPNFQVVFTNNG
                     IEPPLITRVLMGISTVVTNNLAYIIFSFILFSIGSIYFFITNDNIKKLINSLKFKIPF
                     IKKINQLVATTRFSRALSVLISSGIQIVEAIDMSASVIDNEFIYERLKISNNYIKKGN
                     SIGKSLNLANVFPKLFISMANTGEESGKLDKSLNVINKFYENELNNKIEQIMKFIEPM
                     LIVFMGLIIGTFILAMVVPMFDAITNF"
     gene            30056..30415
                     /locus_tag="PC466_001641"
     CDS             30056..30415
                     /locus_tag="PC466_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HDF2769029.1"
                     /translation="MINLINKKRKGFTLVEMIVVVTILGVISSIALVKYSKVQESAKL
                     NADYTNAANIVTAASMAINDDEKTIDSLSVETLKEKGYLNTVPVPQSTSGKFELVIND
                     SGTDISVNINSKQFYPK"
     gene            30468..31340
                     /locus_tag="PC466_001642"
     CDS             30468..31340
                     /locus_tag="PC466_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilus assembly protein PilM"
                     /protein_id="HDF2769030.1"
                     /translation="MAIIKKILNLEINDDYIRLVFLRKSHKKVFIDKSIIKEINFDIK
                     NDSNSIEKIKYIEDVVRFVKEEIGKSKILYKNLYFNIQIQDIVIRNVEVLNTKKKRDI
                     LSMIEFEITQYIPININNYSIKYKVINSKNDKLNIQVILFPKSIIQLIKNISENLNMN
                     PKTININFDILQKLINLNLIENFSEEGVFIECKKSQLIINITKDKKIRETYLLSKEGK
                     SYEFIKRLLRDFKYVYYYGIENCFIEEYFKYTDKSIEVNPLRLKDKVKVENNFDADLE
                     DNRINYINSIGMII"
     gene            31341..31784
                     /locus_tag="PC466_001643"
     CDS             31341..31784
                     /locus_tag="PC466_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769031.1"
                     /translation="MKVDKTINFLNGFKKTKPCNKIYKIIIVLILTCILFKSFMYVKS
                     INELEDYINQNKLVDKSKHTLPTTDKTREKFSKIKLNEIKKIYETIGINSITKISIDK
                     NKLEMEGVCSDLDVLNNLRKIKYIKYYYIDSIVRDGEYYRFRIKS"
     gene            31799..32383
                     /locus_tag="PC466_001644"
     CDS             31799..32383
                     /locus_tag="PC466_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769032.1"
                     /translation="MRLNNREKNLLKILLILVIILASDIAVSYLEENLTSLKNEKQNI
                     INKINNQDNYQIKDNKHIDDKYIESVELNKNEELKNNFNNSFLDKKTNKDIVLLVENE
                     LRDIVNVEYINQESSLDNHNKKQVNLEIKVNGELANVLKLEGVMKKLRLNNKLEKIEI
                     NKLKVNNFDVQNIPNEYKQEKDNIVECKMTVRVI"
     gene            32636..33673
                     /locus_tag="PC466_001645"
     CDS             32636..33673
                     /locus_tag="PC466_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SEC-C domain-containing protein"
                     /protein_id="HDF2769033.1"
                     /translation="MLGRNELCPCGSGKKYKKCCLNKDIVSERACRKTELSQKQYTDL
                     YSKLYDYSRQDKFKEECEKAKEMFYIMQNDSVNEKFERFFNTYLIQDHIMENKKVMTV
                     GFLEENGANLSQSEVSILKSMFESYVSIYEVKEVSAGKIVLKDCLSGNELCTEDVKLL
                     RSFKIGSCMIARIVDIEGTNILIDITISISNEVKDIILKDIMNLFNQYQDVYKDMKSF
                     LIYHTHILYKYIQQLLDPSIAEYLKRERDKNDTKVNSENELAEEECKVLDTLKENVEK
                     ENIDACIEFWNEYKKNHENIKGAENGWAAAVEYYVKKEAGQPITQVQISKKYDISSST
                     LGKRYKDLKIS"
     gene            33754..34119
                     /locus_tag="PC466_001646"
     CDS             33754..34119
                     /locus_tag="PC466_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769034.1"
                     /translation="MSLSLGNAIAVSTNFIKSNPAVPVYNGEEIYAVIYHIEIGYNNG
                     VSPDTKQYIIIDYKEFDLSMDKKNELINVAKEYCKSKGIVENENLEINLLDNEEAENF
                     LEKVFNNMKVIRGLITKKG"
     gene            34124..34441
                     /locus_tag="PC466_001647"
     CDS             34124..34441
                     /locus_tag="PC466_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769035.1"
                     /translation="MDYIGIENITPYENTYEFSVYEYDDEITLGSEKLYVCELRVVLI
                     KVNSLYVERLHKSVEAMVLVKNLKKDLDKTLVVNKIKNFVLDEIWVENLVKENIEVIF
                     VES"
     gene            34489..36093
                     /locus_tag="PC466_001648"
     CDS             34489..36093
                     /locus_tag="PC466_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769036.1"
                     /translation="MLRVSNVKLGIDKDISLLKDVVLKKLKIKEKNLVKYSIYKESID
                     ARKKGKMEFVYSVDVEVKDENKILNSKIKDVTKIKEIRYINVPVGDKKLKNNPLVIGS
                     GPAGLFAGLLLAQMGYEPIILERGLDVDSRTKDISDFWTTRKLKNNSNVQFGEGGAGT
                     FSDGKLTTRIKDIRCRKVLEELVQFGAPDEILYSHKPHVGTDILKNVVKNIRNEIISL
                     GGQVRFNSKVTDIVVSNDSIQSVIINDTEKIDTDTIILAVGHSARDTYEMLYSRGIKI
                     VQKPFAIGARVEHPQDLINKAQYKDFYNHPRLGAADYRLIEHVSNGRTAYTFCMCPGG
                     SVIASASNDFEIVTNGMSEHARDKINANSAFLVNVTPEDFKSDNPLAGVHFQQKYEKL
                     AFELGGKNYNAPVQLVGDFINNKTSLNLGSVEPSYRPGYTLTNLSECLPSFVTETMRE
                     AFISLDKKLNGFAMYDAVLTGVETRSSSPIRIVRDENTLESVSIKNLYPCGEGAGYAG
                     GIVTAAVDGIKCAEKIIQKYTNNTKI"
     gene            36217..37845
                     /locus_tag="PC466_001649"
     CDS             36217..37845
                     /locus_tag="PC466_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HDF2769037.1"
                     /translation="MNIIISLMGGLGLFLYGMNLMGEGLQKSAGTKLKKIIKLLTSNL
                     FMGVLVGTGVTAVIQSSSATTVMVVGFVNAGIMTLKQAIGVIMGANIGTTVTAQLVSF
                     DLTGMAPVALGVGIILYLFGNKPRIKNIAEILIGFGILFTGMDFMKMAVEPLRDYQGF
                     TDLLVTFGRYPLLGLLLGFGITAIIQSSSASMGMLVALAAEGLVPLSAALPILYGQNI
                     GTCVTSLLSSIGANKNARRAAMMHLIFNVLGTVIFLIFLNKPVVSMVTSWDPSNVARQ
                     IANTHTLFNIISVLILLPFTNLIIKLAIKLVPDRAGDIDEDETKTIKYIDDRMIETPS
                     IALANTIKEALRMGEKAKESLNASMEALVEHSTEKIAKTYRRERLINDLQKAILNYLL
                     KLSKAPLDDDSREVVDTLFNTVNDIERIGDHAKNIAELSQVAIDSNISFSEEGQSELD
                     VMYNRVVSAYTYALESMRTDNVDLACKVIKIEEQVDIMEKSCRANHMYRLNNNLCSIE
                     NGVIYLDVISNLERISDHAVNIAQQVIAKRLGND"
     gene            38110..39459
                     /locus_tag="PC466_001650"
     CDS             38110..39459
                     /locus_tag="PC466_001650"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HDF2769038.1"
                     /translation="MGKINFDYSKATEFFCQNEIDVMQPYVDVAHDMLHNKTGLGNTF
                     LGWIDLPKNYDKEEFDRIKKSAEKIKSDSDVLLVIGIGGSYLGSRAAIDMVSHSFRNG
                     LKKEQRKAPEVYFVGHNISSTYIMDLLDIIEGKDISVNVISKSGTTTEPALAFRIFKD
                     YLEKKYGKEEARKRIYATTDASKGALRQLATEEGYETFVIPDDVGGRFSVLTAVGLLP
                     IAAAGLDIDAMMKGANDAREAFQNPDLKSNDSYRYAVARTILHRKGKDVELLVNYEPQ
                     LHYVSEWWKQLYGESEGKENKGLFPASVDFSTDLHSMGQYIQDGKRLLFETVLNVENC
                     KRNITISSEEVDLDGLNYLAGKTVDFVNHKAFEGTLLAHTDGKVPNLVINIPQLDEYN
                     FGYLVYFFEKACGISGYLLGVNPFDQPGVEAYKKNMFALLGKPGYEKEKEELEKRLK"
     gene            39615..40694
                     /locus_tag="PC466_001651"
     CDS             39615..40694
                     /locus_tag="PC466_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HDF2769039.1"
                     /translation="MSRRKKGISLVILVAIISSILSSFLTIILVKDNLVSKSTGSSTP
                     IVVNDDGKSQNIYQAVAEKATPSVVGITTTSVDTSNMFAIPTETQGVGTGIIVDSNGY
                     ILTNSHVISDGQATSVNVLFNDGSTTSGKVVWFDQQLDLAIVKVDKTGLTPAEFADSD
                     KVKVGDISIAIGNPLGLDFQKTVTQGIISGLDRTIQTEKTNMTGLLQTDASINAGNSG
                     GPLLNQKGQVIGINTAKASQAEGLGFAIPINTAKSIVEEVIKNGKYEKVTLGIKGTDV
                     SNYEAATGTKLSTDKGVYVAEVISGSSAEKAGVKVGDIITKVGDTDITGMNDLNKKLY
                     TFSKGASTKITVNRGGKAVTINVNF"
     gene            41039..41947
                     /locus_tag="PC466_001652"
     CDS             41039..41947
                     /locus_tag="PC466_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HDF2769040.1"
                     /translation="MNPLVINLQKCSIHDGPGIRSTVFFKGCPLECVWCHNPESQTYT
                     KQVLYNEERCSKCEACINICPHKAIYKGETKICLDQDKCEFCETCLDYCVNNAREIVG
                     QEYSVRDLVKEIEKDRIFYEESGGGVTLSGGEVMAQDMDFICGVINMCKSKGIHVAID
                     TCGYAKSENYERVAKCADLFLYDIKLIDEDKHIKFTGKSNDLILKNVKILSELGVNIN
                     IRIPLIVGVNVDDENLEVKKMIEFLKPLNIQAVSLLPYHNIGKHKYDKIYKKYEGEEL
                     QRPSEEKLEEIKRLFEASNFNTKIGG"
     gene            41952..44321
                     /locus_tag="PC466_001653"
     CDS             41952..44321
                     /locus_tag="PC466_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HDF2769041.1"
                     /translation="MARGTFERTKKLREESINAEPHISIERAVLMTEAYKKYEGSVEI
                     PVLRALSFKHYIENRTLSINDGELIVGEKGDSPNGAPTYPEICCHTMEDLEVMHNRDI
                     INFSVSEEARKIHKEEIIPFWKKRQTRDKIINAMTPEWLAAYEAGMFTEFMEQRAPGH
                     TVCGDTIYKKGFLDLKKDIEARLKELDFLNDLDAYNKKADLEAMAIACDAMVILGKRY
                     AEKARQMAEEETDEAKKKDLLLIAETCDVVPAHKPETYHQAIQMYWFVHIGVTTELNI
                     WDAFTPGRLDQHLNPFYERDVENGILDRDRAQELLECLWVKFNNQPAPPKVGITLKES
                     STYTDFANINTGGINPDGQDGVNEVSYIILDVMDEMKLIQPSSNVQISKKTPQKFLKR
                     ACEISRKGWGQPAFYNTEAIVQELMEAGKTIEDARLGGTSGCVETGCFGKEAYVLTGY
                     MNIPKILELTLNNGYDPISKKQIGIETGDPRNFQSYEELFEAFKKQLHYMIDIKIEGN
                     AVIENICAKHMPCPLMSTIVDDCIEKGKDYQRGGARYNTRYIQGVGIGTITDSLTAIK
                     YNVFDKKKFDMDTLLKALDANFEGYEAILNLVSNKTPKYGNDDDYADEIMQEIFNAYY
                     NEVTGRLTVCGGEYRVDMLPTTCHIYFGEIMGASPNGRLCAKPVSEGISPEKGGDTNG
                     PTAVIKSCAKMDHIKTGGTLLNQRFAPSVVQGEKGLDNMANLVRAYFNMDGHHIQFNV
                     FDKNVLLEAQKNPKDYKDLIVRVAGYSDHFNNLSRTLQDEIIGRTEQTF"
     gene            44646..45449
                     /gene="proC"
                     /locus_tag="PC466_001654"
     CDS             44646..45449
                     /gene="proC"
                     /locus_tag="PC466_001654"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HDF2769042.1"
                     /translation="MKTLGFIGSGNMGSAMIGGIVQSGLVKAEDITVSDLSQVALDKV
                     KEEFGINTTTDSKVAVTNSDVVIVALKPNICEKALTPLKELIDANKIIVSIAAGKTIE
                     SLESFIGSDKKIVRVMPNTPALVGEGMSALCKNSNVTDEELNMIKALFESFGEAEIVS
                     EYLMDTVTGISGSSPAYVFMFIEAMADAAVLAGMPRQQAYKFASQAVMGSAKMVLETG
                     KHPGELKDMVCSPAGTTIEAVKVLEEEGFRAAVIKSIVACIDKSKDMSK"
BASE COUNT        18723 a         4833 c         8264 g        13796 t
ORIGIN      
        1 atataaagtt tttgaaatat aaagtttttg tatctaaaat attttatttg taaaatagta
       61 attaattatt gtaagctata atatgagagt attatggtta atgtgaattt taaagatatt
      121 attaaagata taaattagaa tactattaaa cggataaatg gaggagttat tatgtctaag
      181 atattagtag tagatgatga gttagatatg ttaaagttga ttgaaaatgt gttgaaaaga
      241 gatggacatg aagtaaaggt aattagtgat gtagaaaagg ctatgaacat ggattttaat
      301 tattttaatc taataatatt agatgttatg atgcctaaga tggatggttt tgaagtatgt
      361 aaaactataa gaaataaggt tgattgtcca atactgtttt tgacagcaaa aaatatggaa
      421 agtgatatta tgtacggtct tggcataggt gcagatgact atataaccaa accttttggt
      481 gtaggagaat taagggctag gataactgct catttaaggc gagaaagtag agaaaaaaag
      541 aatttattaa ctatctcaaa tgttcaattt aactttttag gcaaagaagt ttcaattgat
      601 ggtaaaaaaa ttaattttac taaaagtgaa tatctaatat gtgaatttct agcaaaaaat
      661 aagggacaag tattttcaaa agaaagaata tatgagtcgg tatatggttt tgatggagaa
      721 agtgatataa gtactatcac agagcatata aaaaatatac gaagcaaatt aaaacaatat
      781 gatatttata caatagaaac tgtatggggg atagggtata aatgggtgta ataagtataa
      841 gtgttgctta gtgaaaatat tatatatatc tacaaaatgt ttgtaaaata ttaatctata
      901 tattaaaatt taatttatag attaatattt tttgtaaatg acaaaattgt aaggtatttt
      961 gttataaaat attaagattc atagtgtata ctaataatat agtatttagt ataaatcttg
     1021 agcaaaggat ggttatttct aatggataga ctaaagaata ttagaaagag tttactacag
     1081 tatacatttt tatttttgtt aataggtata acaatttacc tagtgtttaa aacattggat
     1141 attaaaatgc tatcaaatgt tatggttatg gtagataaga agtttttatt cataggtgct
     1201 ttggcaataa tgtgtcacat aatgcttgaa ggagtagtaa tgaagataat tatagaaagc
     1261 actcacaaag ttaatattag atttattggt tttaagctag ccattatggg attttattat
     1321 aatttaataa ctccttttgc ttcaggaagc caaccagtac agatatatgt acttaaaaaa
     1381 tgtaaaatgc cacttagtaa ggcaagtgca gttgttacca ataagtctat tattttccaa
     1441 atagtggtta ctttttattg tacaatactt gtattaatga attttgctat gttagaaaaa
     1501 caaatgaaaa tgattatgcc tctagtgttt ctagggatag ccattaattc atttgtctta
     1561 attatgataa tattagttat tttaaaccct aaaaaaataa aatattttat gagaattact
     1621 ataaagcatt tatcaaaaat taagttttta aaatttttag ataataagat tgaatccata
     1681 gaaagtttta tagatgatta tagtaaagca ataaattttt ttgcaaagaa taaaaaggta
     1741 ttaatttcaa ctataatagt aacttttatt caattaagtg cttactttag tgtttcattt
     1801 tggatatata aagcatttaa tttacaaggt tatagctata tttatatact gacattacaa
     1861 gcatttttat atatggcaat atctccaata ccaacacctg ggaatgtagg agctaatgaa
     1921 ttagcctttt tcactatatt caaatcagta ttccctcaac ctttgatggg atatgcagta
     1981 tttttatatg gtggatttat gtactattta attctgattg gaagtggaat atttactgta
     2041 attactcact atagaatgaa aaatagaatt ggcagaaata ttgttttaag tgaaaactaa
     2101 ataagtttaa agaatatata ttgagtatat taaaaaatat gtcataagaa ctagaatatt
     2161 ttaattaaat ggttgaaata taaagattat tatgacatat tttttttgaa atttaagagg
     2221 aattgtgaga aaattgttga atttaataga tagtattgca aaatatttat gattttgcat
     2281 attataaaaa cactcattat ctttaagata aattttactt atcaggggat aaatctaagg
     2341 ggggaattgt atggagaaaa aaattttaac agtttgtcca tactgtggag ctggatgcca
     2401 attatatcta gtagtaaaag ataataagat attaagagct gaaccggcta atggtagaac
     2461 aaatcaagaa agtttgtgtt taaaaggtcg ttatggatgg gattttctaa atgaccctaa
     2521 aattctaaca cctaggctaa aaaagccaat gataagaaaa caaggtgtac tagaagaggt
     2581 tgaatgggat gaggctataa actatacagc ttcaagacta aatgaaatta aagaaaaata
     2641 tggacctgat tctattatgg gaacaggttc tgcaagagga cctggtaatg aagcaaacta
     2701 tataatgcaa aaatttatga gagctacaat aggaactaat aatgttgacc attgtgctcg
     2761 tgtatgacat gcaccatctg tagccggtct ggcttactca ttaggtagtg gtgcaatgtc
     2821 taattctata ccagagatag aaaatgcaga tgttttattt atatttggat ataatggagc
     2881 agattcacat ccaatagtgg caaatagaat agtaaaagct aaaaaaaatg gtgctaaatt
     2941 aattgttact gaccctagag taactgaatc tgcaagaatt gctgatatac atctacctat
     3001 aaaaggtgga acaaacatgg ttttagtaaa tgcttttgga aatgtattaa tagaagaagg
     3061 tctttacaat aaagaatttg ttcaaaatca tacacaagga tttgatgagt ataaagaaat
     3121 tgttaaacca tatacagcta aatatgctga aaagattaca ggaatcccag aagagcttat
     3181 aagaaaagct atgagagaat atgcaaaagg gaaaaaagct atgatacttt atggaatggg
     3241 tgtctgtcaa tttggtcaag ctgttgatgt agttaaggga cttgcatcaa ttgctctact
     3301 tacaggtaat tttggtagag aaagcgttgg aataggacct gtacgtggac aaaataatgt
     3361 tcaaggagct tgtgatatgg gagctcttcc taatgtatat cctggctatc aaaatgtaac
     3421 tgatgataag ataagagaaa agtttgaaaa aacttggggg gtaaaattat ctcctaataa
     3481 tggttatagt ttaactcaag ttccagactt agtactaaaa gagaaaaagc ttaaagctta
     3541 ttatatattt ggagaagacc cagtgcaaag tgacccagat gcatcagaag ttagagaagc
     3601 attagatgaa ttggaatttg tcattgttca agatatattt atgaataaga cagcacttca
     3661 cgctgatgtt atacttccag ctacttcttg gggagaacat gagggagtat atacatgtgc
     3721 agatagagga ttccaattga tgagaaaagc tatagagcca caaggagatg taaaaccaga
     3781 ctggcaaatt ataagcgaaa tttctacagc aatgggatat cctatgaatt ataaaaatac
     3841 taaggaaata tgggacgaac ttagacaatt atgtccaagt ttcttaggtg ctacttatga
     3901 aaagatagaa actcaaggat gcgttcaatg gccttgtaag agtgaaagta tggaagataa
     3961 aggaactatg tatctgtatg aaggtcaaaa gttttctact cctaatggta aaggtaattt
     4021 gttcgctgct gaatggagac cccctatgga agttgaagat gatgaatacc catttagttt
     4081 atgtactgta agagaagttg gacactattc agtaagaaca atgactggta attgtagaac
     4141 acttagttca ttagaagatg aaccaggacg tgttcaaata aattctaatg atgctgaaaa
     4201 attaggaatt gaagatgatg aattagttag aattagttca agaagaggaa gtgtaataac
     4261 aagagcaaca gttactgata gagttaagga aggtgcaaca tatatgactt atcagtggtg
     4321 ggttggagct tgcaatgaac ttacaatagc aaatttagac cctatatcta aaacaccaga
     4381 gtataaatat tgtgctgtta aacttgaaaa acttgaagac caagaattag cagaaaaatg
     4441 tgtaagagaa gagtatcaaa gtttgaaaga caaaatgaca gctacaaata tctaatgatt
     4501 tattagattt aagatttata aaaggcagaa aggctaatat tttatgaaca atatatactc
     4561 aaaaactaaa ttacaagaaa atagtaagga taaagttttt gaaaatagtt atagtctagt
     4621 ggactacaaa tatttaaatt cttttaatgt agaagtaagc aaaataaatg aacatgaagt
     4681 atcaatagat aatgaagaaa taattgcaga atatccactt agttttattt taaatgataa
     4741 atatgtaaat acatttttat gtaccccata taatttagag gaacttatag taggattctt
     4801 gaaaacaaaa ggatacatag aaaacaaaaa aagcttatta aaatttgaga taaatgagag
     4861 tgaacgtttt gcaaaagtaa ctattcaaga gaaacaaaaa aatcaagatg agcaaattat
     4921 atttttaaat tcactagact atataacatg tgcttctgta aagagcaata taaaaataaa
     4981 ttatgatacg atttacagta taatggatag aaatttaaat tcatcagaat tatttaaaaa
     5041 tactggtggg gtacatagcg tatctgtatt taattttgat aaaaaaatag tcacttgtga
     5101 agatgtagca aggcataatg caatggataa ggctattgga ttttgtgttt taaatgacat
     5161 aacattaaaa gataaaattg tggctgtaag tggaagaata tcattggaaa tgatattaaa
     5221 agcagctatg actcaaattc ctattgtagt atcaaaatca gcaccgacta atttatcaat
     5281 agagctttct aaaaaattaa atataacgct tattggattt gtaagaggaa gacggatgaa
     5341 tatttatgca aatccacaga gagttatcaa aaagtgagaa taagtatatg tgtactaaaa
     5401 aagaagaaca aaaatgttca aagtgtgaaa tctgtggagt attaattgac gatactgata
     5461 aggtgtataa taacacatac aatttgtgca aaaaatgtaa acgaaatata agtactgaga
     5521 aaatagtgaa atatataaat atatatgatg aaagtaagta gacatatgat gaaagtaact
     5581 agagggttgg aaatatacaa attgaaaggt gggataatat gaaaaataaa ataggctctt
     5641 ttgtaatagc ggacccaaac aaatgtacag gttgtagagc ttgtgaagta gcttgtttta
     5701 caatgcataa tcagcataat aatgtgggtt atacagttgg aacagttgat atacctgtta
     5761 tacctagact ttatttagta aaaggtgaca atttctgtat gccaatacag tgtagacatt
     5821 gtgaagatgc tccttgttta aactcatgtc cacaaaaagc tatagtcaaa gaaaacaata
     5881 ttatgtctgt aaatgaagaa aagtgtatag gatgtaaaac ttgtctgcta gcatgtcctt
     5941 ttggagctat agacttactt ccacaatatg aagatggtaa agaagtagaa caagtaattt
     6001 tagatgaaaa taagaagata gcttataaat gtgacttatg taaagacaat gaaaaaatag
     6061 cttgtataag tgcatgtcct caggaagcat taaaacttgt tactccaata gatgacaaaa
     6121 aagctaagaa tagacaagct gcacttagtt tattgttaac aaataaataa aggatacagg
     6181 ggtaggtgac gtttatgata ataaatatag ataaggattt atgtactgga tgtagagaat
     6241 gttcaaaggt ctgtccagta aatgctattg aaggtgaaga gggaaagcca caagagataa
     6301 atttagatag atgtgttatg tgcggtcaat gtgttcaaac ttgtaaatct tatgcctcag
     6361 ttatagatga aggatttgag tttttacaag agaaaaaaca agaaagagag ataccagagt
     6421 ctataaatga acctatattt gcagcataca atgtatgtga tatagataag gtaaagaaag
     6481 ctttaagtga cccaaatgta ttcactatgg tccaatgtgc accagcagtt agagttgctt
     6541 taggagaaga tttcggatat tatttaggat acttaggtgc tggaaaaatg gcagcagcac
     6601 ttagagcttt aaattttgat agagtctacg atactaattt tgcagcagat ttaactataa
     6661 tggaagaagg tagtgaatta attaaaagag tgacagaagg tggaactctt ccaatgttta
     6721 catcttgttg tccagcttgg gtaaaattca tggaaaaaaa ttatcctaaa ttaactaatc
     6781 atttatcttc ttgtaaatca cctcagcaga tgggtggtgc aatatttaaa acttatggtg
     6841 cagagataaa taatgtagat gcatcaaaga tatttagtgt ttctataatg ccatgtacat
     6901 gtaaaaaata tgaatgtgat agagaagaaa tggattctag tggatataga gatgtagatg
     6961 tagtattaac tactagagaa ctagcttatt taataaaaga catgggaatt gattttaaaa
     7021 atttaagaga agaaaaattt gatagtcctt taggtagtta tagtggagct ggaactatct
     7081 ttggtgttac tggtggggtt atggaagctg ctataagaac aggatatgag cttataactg
     7141 gagaaagtat tcctgatgta gaagtaaaac aagtaagagg agaaaatggt tttagaaagt
     7201 caactattaa aataggagac ttagacttaa gagttggagt agtaagtgga ttaaaaaatg
     7261 taataccagt gcttgaagac ttggaaaaag gaaaattaga tgtagatttt attgaagtta
     7321 tgacttgtcc tgttgggtgt gtaagtggtg gaggtcaacc aaaaatttta ctagaagaat
     7381 ataaggaatt ggcttatgaa aatagaacaa aagcaacata cgtgcatgat gaacatttag
     7441 caattagaaa atctcatgag aatcctgata ttaaaaaact gtatgatgaa tatctggtag
     7501 aaccattagg agaaaaatct catcatctat tacacactac atattgtata ggaaaggaag
     7561 tggctaagtg atgaactatt ttgttatagc agaccctgat aaatgcatag gatgtagaac
     7621 ttgtatgata ggatgtgtag ttgcacattc agatgaagat attttttacc aaaatccaga
     7681 tgaaataaat tttaatccaa aactttctgt cataaagaca aaagaagtaa gtgctccaat
     7741 acagtgtaga cattgtgaag atgctccttg tgcaaaggca tgtccaaatg gtggtatagt
     7801 tagggttggg aacacaataa aaataaatga agaaaattgt ataggatgta agacttgtat
     7861 gttagcatgt cctataggtg caatagacat agttacatta aaagatgtag atgaaggaaa
     7921 gctttgcttt agagaaagaa tgacagcaaa taagtgtgat ttttgtatag aatcgccaga
     7981 agggcctgca tgtgtaaatg tttgtccaac taaggcattt actatagtta aggatgagga
     8041 tatagatagt aaagttaaaa ataagagaaa attagctata ttgtaatata aaaaagatgg
     8101 agttttattt atgattaaaa gctccatctt ttttattata atatttatat atctaaaaat
     8161 caattattgc attagtttat ctaatctttc tttattcaat tttttcattc ctatagaagt
     8221 tataataagt aaagtatagg caattataac tgataaaatt ataatagacc aagaaaatct
     8281 gtatccaaaa ttatcaacta acaatccaaa taatgttgaa cctaatgcaa atcccactgc
     8341 aaaaattaat tgtacgattc catatatgct accaaactcc ttttgaccaa agaaagagcc
     8401 agttaaataa gcaggaccaa tcatataagc aaatacagaa agacctttca aaatggcaaa
     8461 tacaaatgca aaagtagaag atttatctac caatagtaat gataaagttg ctataagaac
     8521 caatacaaaa gatataataa gtggctttgt ttgaccgaat ttatcaaaca ataatcctcc
     8581 aaataaatta ccaatgagag caaataaagc aaatgtggag cctactgttc ctattagaat
     8641 aggatttaga taatttctaa gataagttgg atattgtacg gataatgatg aaacatatat
     8701 accaacaaat ataaatccaa tagtcataat ccaaaaatat ttaatttttt tagcttcttt
     8761 taatgtataa ccccatactg aaggagaaat tgtatcagat gctttctctt ttttaccttt
     8821 agattttacc ttttcattaa tatctttagg catcctgagt atgaataata ttacaggtat
     8881 accaactatt aatgctataa ttccaaatat tagataagaa tgactgtatc cttgagttgc
     8941 taataagcga actgcaagtg gttgtagaaa tatactacca atagaaccac cagcaaaagc
     9001 aaagcccaaa gcttttcctt tgctttcttc atcaaaccaa gcacttatta aaacaggtat
     9061 tcctatagca gatataattg tagcgccaat ttgaacaata catgatacag tgtaaaattg
     9121 ccatagttca gtacatatag aaaaagtagc aaaagcaata ctagaaatta tacaacctaa
     9181 taaatatagt atcttaatat tgactttaga aaataataca cctataaaag gtgatgcaat
     9241 tgctgaggca atagtaccaa tagtgaatat tagagaaaaa gaagctaaac taaagccttc
     9301 tccttctaca acataactta taaattgagg ctgtatactt gctacaatac taaatggaac
     9361 agcttgtatt aacatacaac caagtactat aacccaagca tttgaaaagt ttttaatgct
     9421 aaatttattg tttagtaatg tattcatggt atctctcctt taggttatga tttgtagata
     9481 ttaatctaat tattctaatt ttatatatta gttttggata gcctaactat ttaaatgtaa
     9541 tttgggtatt aatataaaaa ttaactataa aaattgatta ttttaaatgt atggggtaaa
     9601 ttaaagtata taaataaatg aaaggatgga taaaatgtca tttgaaaaaa taaataataa
     9661 taacctagat aaaatacaca ataggaagtg tattatgctt gtaaacttta ataaaaaaga
     9721 attatcatta attaaaaacg taagtaactt tgctggaata agagaccata taatcttaag
     9781 tgaaaaaaac ggagagaata taataagaga cattttagat ggaaatatat caagtgaatg
     9841 tgaaaatggg attaagagta agtctgtaat atttaataac actccaagca cacaagtaaa
     9901 tgcattttta gaaggtctaa aaaaagtgag aataaataga ccttttacag ctatggtaac
     9961 agagacatct attgattgga cattgaataa tttaatagaa aatttagttc aagaacgtaa
    10021 tgctatgtct ttaggaaaaa caattgaaca taagtaaatt taagatatct tatagtaatt
    10081 ttaactaatg tacattgagt atcatattat attttagaat ataaaatttt aaatgtgggt
    10141 agatagagga gatttgagat gaaagtttta tttacaataa attatggaaa agaaaaattt
    10201 gataaaataa gagaattagg ctatgatgtc atacattact ctgaagatag tattgaaaat
    10261 aatgaggatg taaatacagc agatgtacta gttacataca atccatttga gagattagat
    10321 atttctaaga tgaaaaattt acaatatata cagacaacta gtgtaggtat agaccaactt
    10381 ccaaaagaag aggtattgaa gagaaatatt aagatagcta ataatagagg cggatatagt
    10441 gtacctattg gtgaaagtat tgtattgtat attttagaaa tatataaaaa tagtgcaaaa
    10501 ttttttaaac aacaacaaaa taaagaatgg aagatggatt tttctgtatc agaattgtat
    10561 ggacaaagag ttggattttt aggaacaggt actatatctt cagaagcagc aaaacgatta
    10621 aaagcttttg gtgtagaaat atggggtgtc aatactgatg gaagtagtaa aaaatacttt
    10681 gataagtgtt ttgctactga agatatgaat attgtatttg aagaatgtga tatagtagtt
    10741 gtagcaatgc cttctacaaa aagtacagat ggaatagtaa acaaagatat gtttaaactt
    10801 atgaaagatg gttctgtatt tataaatgta ggtagaggaa atacagttaa tcagaaagat
    10861 ttagaagaat gtgtagagaa atttagaggg gtagcactag acgtatttga aagtgaacct
    10921 ttaaacaagg acaataagtt gtgggagtgc gaaaatgtca tagtaactcc tcataattct
    10981 tgggtgtcag ataaaaacaa agagagaaca tttaatatgg tttataataa tttgaaacac
    11041 tatataatgg agaataaacc tgtagataat gttgtagaca tatcaagagg ctattaaaaa
    11101 taaaaaattt tgataaaaat aaaaactctt attagtcgta ttaaagatac taataagagt
    11161 tttttttgta ataaatttaa agtcaaaaaa gtgatatact aaaaaatata taaataggag
    11221 ataattaatt atagggaaat ttcaaaataa tttaatttta aaaatatgaa gaggtgcaaa
    11281 aagtgagcgt aaaagatgaa attaataaac ttatagagac aataaactac cataatgaaa
    11341 ggtattataa tcaagatagc ccagaaatat cagattatga atacgataag ttaatgaagg
    11401 agttaatttc tttagaagaa gaacatccag aactaaagag aattgattct ccaacaaata
    11461 gggtaggagg taagccatta gataaattca atcaaattgt acataaaact cctatgttga
    11521 gtttatcaaa tgctttttca gagcaagatt tgagagattt tgataagaga gttcaagaat
    11581 atgtgggaga aaatgttgaa tatgttgttg aatttaaaat agatggtctt tctgtaggtc
    11641 taacttataa caatggagag tttgaaaaag gagcaactag aggagatgga gttgtaggag
    11701 aagatatttc tcaaaactta atgacagtaa aaagcatacc tcttaagata aatgataaaa
    11761 aagaactaat agttagagga gaagtatata tatcaaaaga taattttaga aaagtaaatg
    11821 aacaacaaga agaacaagaa cagccattat ttgctaatcc aaggaatctt gcagctggtt
    11881 cattgagaca attagaccca aaactaacag caaagagacc attagatata tttgtattta
    11941 atatggaaaa tatagaagaa tatgatttag aaagtcacag tgaatcacta gagtacttag
    12001 aaaaactagg attttcagta agtcagagtt ataaagtttg taaaagtata gatgaagtta
    12061 ttgagcatat tgaatactgg acagataaca ggggtaattt agactacgaa atagatggta
    12121 tggtaataaa agtaaacaat ataaaacaaa gagacgaaat gggatataca gccaaaagtc
    12181 ctagatgggc aattgcatat aaattcccag cagaaaagaa gaaaactaaa atagtagata
    12241 taatagtaga agttgggaga actggtacaa taacaccttc agcaattctt gaaccagtca
    12301 gacttgcagg tactactgta agtagagcta cacttcacaa tgaagattat ataagagaaa
    12361 aagatataaa aataaatgat acagtattag ttcaaaaagc aggggacata atacctcaag
    12421 ttttagaagt tataaaagag gaacgtactg gagatgaaat agattttaaa atgccagaaa
    12481 agtgtccagt ttgttcagag ccaacaataa gattagaagg agaggctgct gtaaaatgta
    12541 tcaatatgtc ttgcccagcc caaataagaa ggggaattat acactttgtg tcaagggatg
    12601 caatgaatat agatggattg ggagaatcta taattacact gctattaaat gaaaaaatta
    12661 ttcaagatgt atctgattta tattatataa aaaaggaaga tgtagtcgac ctagagagaa
    12721 tgggcgaaaa atctgctgac aatttaataa attcaattga aaaatcaaaa gaaaatgatt
    12781 tatggagact tataaatgga ttaggtatta aatttatagg agttaaagca gctaagatac
    12841 ttgcatataa ctttaaggat ttagatgaag taatttctgc aactagtgag caactagaag
    12901 aattagagga atttggaagt ataatggcaa acagcgttgt cgagtttttt aaggaagaca
    12961 aaaatatgaa cgttataaac aagttaaaaa atgtaggagt aaatacaaaa tcattggata
    13021 atacaggtga aaaagtagaa aaaatatttg aagggatgaa aatcgtattg actggtacac
    13081 ttcctacatt aaaaagaaat gatgcgaaag atatgataga aaaaagaggt ggaaaagcta
    13141 catctagtgt tagtaaatcg acaacatttg ttttggcagg tgaagaagct ggttctaaac
    13201 ttactaaagc aaatgattta ggaattaaag ttatagatga agagagattt ttagaattat
    13261 taaagttatc atcgaaagat gaagtaaaag ctgtattaga gagttaaaaa gtcgcttaat
    13321 ttagtagaaa actactataa ttaatgatag aatagttcag taagctaata agattacgaa
    13381 aaatgacaat aattaatatt tgacaaaatt aaaaattata aaaataaatt tataaaaaat
    13441 aaaaaatatg agaaaggata taaaaaatga ccagaagtta tgatagaagt aacgaacaga
    13501 taagacctgt aaagataact agagattata caaagtatgc agaaggttct gttcttatag
    13561 aaatgggaga gacaaaggtt atatgcactg catcagtgga agaaaaagtt cctccttttt
    13621 taagaaatag tggtactgga tggataaatg ctgaatattc tatgctacca agagcaacac
    13681 aacaaagaaa gataagagat gcatctaggg gaaaaattga tggaagaaca caagaaatac
    13741 agaggttaat aggaagagca ataaggtctg ttgtagactt gaataaatta ggagaaagaa
    13801 ctatttgggt agattgtgat gtgattcagg cagatggtgg aactagaact gcatctataa
    13861 caggggcatt tgtagcagtt gcagaagcaa tatataaatt atataaagca aagacaataa
    13921 aagagatgcc aataacaaat tttgtatctg caattagtgt tggtattgta aatggaatac
    13981 acatgctaga tttatgttat gaagaagatt ctaaagcaca ggtagatatg aatataataa
    14041 tgactgataa gtgtgagttt gtagaagtac aggggacagg agaagagaaa cctttttcaa
    14101 gagcagattt aaatttattg ttagagttag gcgaaaaagg gaataaagaa ttaataaggc
    14161 ttcaaagaga agctttaggt gaaatagcag atgagatatt gggtatggat tatggtaatg
    14221 aagtagtgat tgctactaat aatgctcata agctagaaga aataggtgaa atcttaaaag
    14281 attttgaata taaagtgtac tctttaaaag atgttgattt agcaggtata gagatagtag
    14341 aagatggaaa aacatttgag cataatgcgt tgataaaagc tagagcaata gcaaaaaaga
    14401 ctaaacttat agcaatatca gatgattctg gcttagaagt agatgcttta ggcaaaaaac
    14461 ctggtgttta ttcagctaga tatgcaggag aacatgcaac agatgaagaa aatagaaaaa
    14521 aactgttaaa agctatgcaa aatgtaccaa tgagcaaaag aaatgcaaga ttcgtctctg
    14581 caatagcagt agtttttcct gatggaaaag aatttgtagt aagaggaatt tgtgaaggaa
    14641 tgataggatt tgaagaaaaa ggtaaaaatg gttttggata tgatagctta tttatagtaa
    14701 aaggatatga taagactttt ggtgaaatac ctagtgttat aaaaaattca atcagtcata
    14761 gagcaaacgc actaaaactt atgaaacaag agtttataaa aagggtagtg aagtaatgaa
    14821 aataggcata gtaagcgaca cacatatgat gattaaaaat atggaaaaaa caataccata
    14881 tttgaaagaa tgtgacctaa taattcatgc aggagataac tttactgatt caagatatat
    14941 tcatagcatg actaatgtag gtattattgc agttaaaggt aattgtgact ttgatgctgt
    15001 tgaggaagaa gttgtctttg aagtggcaaa taaaaccata ttcttatgcc atggagataa
    15061 gtatggtgta aaatatggaa ctaatatgtt agaaaaaaag gcaactgaag ttgatgctga
    15121 tatagttata tttggccata cccatacccc atttagagaa attaaagatg gtgtacttta
    15181 cataaatcct ggaagcactt cacttccaag aggagtatcg tataaaagtt ttgtcattat
    15241 ggatatagaa gaagatgaca taaaaattga agaaatacgc atataaaggt gtatttatct
    15301 aaaaaaatgg caaaaaacgc tcaaaaaatt aaattttatc aaataagtac aacgatatta
    15361 atggaacact tgtaaataaa aaaacttatg tgatataatt aagtggttga attataaata
    15421 gaatgaatta taataccgtt atcgggtatt acataaatat cactaggagg attagaagga
    15481 tgaaagcaga actaattaaa aaagagggta ataaagttac tttaaaaata acagtagata
    15541 acaataaatt tgaagcagca gtaaataagg cttataataa aagcagaaat aaatacaata
    15601 tacctggatt tagaaaaggt aaagctccaa gaattgttat agagactcaa tatggaaaag
    15661 gtatattcta caatgatgct atagaaatat tattcccaga agtttatcca gaagctatca
    15721 aggaattaga catagaccca atagacaatc cagatttaga tatagaagaa ataagtaaag
    15781 ataatgggtt ggttatggtt cttaatgtag aagttaaacc agagtttgaa ttaggaaact
    15841 acaagggtat agaaatagct aaggttgaga atactgtaag tgacgaaaat gttgatgcta
    15901 aactacaaga aatggttgaa aaaaatgcca gattagtaag tgtagaagac aaagctttag
    15961 aagatggaga tacagctata atagacttcg aaggttttga aaatggtgta gcttttgatg
    16021 gtggtaaagg tgaaaattat aacttagtta taggttcaaa cacatttata ccaggatttg
    16081 aagaacaatt agtaggtaaa aaagctggtg aagaagtaga agttaatgtt actttcccag
    16141 aagaatatca ctcacaagat ttagctggaa aaccagttgt atttaatgta aaaataaatg
    16201 atgtaaaagt aaaagaatta tctgcacttg atgatgaatt tgctaaagat actagtgaat
    16261 ttgattcttt agatgaatta aaagcagatg taagagctaa gttagaagaa gaagctaaaa
    16321 atagagcaga tgcagaaact agaaattcag tagtagaaaa agttgctgaa aatacagaaa
    16381 tagaaatacc agaagttatg atacaacatc aaatagataa tatgttaaat gaacttaact
    16441 accaattaca atatcaagga tttggattac aacaattact agagatgact ggtagaacta
    16501 tggaagaatt aagagaagag agaaaagaag atgctaaaaa attagttaag tcttctttag
    16561 tattagaagc aataactaaa gctgaaggaa ttgaagcaac agaagaagaa tttaaggctg
    16621 agttagaaaa aatggcttct gcttacaata tggaagtaga aaaaatagaa gcttctttaa
    16681 gagatgctga caaagaagat ataaaaggtc aaataaaaat aagaaaaaca atagatttat
    16741 tagttgataa tgcaacaata gcttaataaa ataaacgcta actaatatag ttgacgttat
    16801 gaaatgttta gtatataatg atgtgcaaat ataatttagt taaatgcgta taataattta
    16861 cagtagctta aaaaagctac tgtaaattat atagaataaa gggggtatga aaccatggca
    16921 ttagtacctg tagttgttga acaaacagga agaggagaaa gatcttatga tattttttct
    16981 agactattaa aagacagaat aatcttctta ggagatcaag ttaacgatgc cacagcaggg
    17041 cttatagtag cacagctatt atttttagaa gctgaagacc cagacaaaga tatacattta
    17101 tatataaatt ctccaggagg aagtataact tctggaatgg ctatatatga tactatgcaa
    17161 tacatcaaac cagatgtaag tactatatgt ataggtatgg ctgcttctat gggagcattc
    17221 ttgttggcag caggagcaaa aggaaaaaga ctagcactac caaatagtga aataatgata
    17281 catcaaccat taggtggagc tcaaggtcaa gcaacagata tagaaattca tgcaaagaga
    17341 attttaaaaa taaaagaaac tttaaatgag atattatctg aaagaactgg tcagccatta
    17401 gaaaaaatta aaatggatac tgaacgtgat aacttcatga gtgcactaga agccaaagaa
    17461 tatggtttaa tagatgaagt atttacaaag agaccgtaga tagagagagg tgttaatatg
    17521 tctaaatatg aagaaaaacg acaattaaag tgttcattct gcggtaaaaa tcaagatcaa
    17581 gtaagaagat taattgcagg tccaaatgta tatatttgtg acgagtgtgt tgaactttgt
    17641 gacgaaatta ttcaggaaga aatagaagat actatagatg aagatactac atctttacca
    17701 aaaccaaagg aaatgatgga gattctaaat gattatgtaa taggtcaaga aaaagctaaa
    17761 aaagctttat cagttgcggt ttataatcat tataagagaa tatacagtaa aaaatctagt
    17821 agtaaggata tagaaattca aaagagtaat atacttttat taggacctac aggttctgga
    17881 aagacattac ttgctcaaac tctagcaaga actctaaatg taccttttgc aatggcagat
    17941 gctacatcat tgactgaagc tggatatgtt ggagaagacg ttgaaaatat acttttaaaa
    18001 cttattcaag ctgctgattt tgatatagaa aaagctgaaa gaggtataat atatatagat
    18061 gagatagata agattgcaag aaaatctgaa aacccatcta taactagaga tgttagtggt
    18121 gaaggtgttc aacaagcact tctaaaaata ttagaaggta ctgttgcaaa tgttccacca
    18181 caaggaggaa gaaaacatcc ccatcaagaa tttttaaaga tagatactac taatgtatta
    18241 tttatattag gtggagcttt tgatggatta gagaagataa ttcaaaaacg tggtggagat
    18301 aaaacactag gttttggagc taaaatagaa agtaaaaaag aattagattt agggaagctg
    18361 tatgaaaaag tacttccaga ggatttatta aaatatggta taataccaga gtttatagga
    18421 agaataccag ttttagctac tttagagttg ttggatgaag atgcattaat gcagatatta
    18481 caggaaccta aaaatgctct agtaaaacag tataaaaagt tattggagtt agatgatgtt
    18541 gagctagaat ttgaagaagg tgctcttcgt gcaatcgcta aaaaggctat agaaagaaat
    18601 acaggagcta gaggacttag aagtatagtt gaaagcgtaa tgatggaaac tatgtttgaa
    18661 gtaccatcta gagataatat aaagaaggtt atagtaacag agaaatctgt gaacgaagac
    18721 tcagtaaatc ctatcatagt acttaaggat caagaggaaa gtgcataaga tgatgaaaag
    18781 gagctttaaa agctcctttt tttatgttaa tatgctaaat ataaaatagg tatcattatc
    18841 ataaaaatgt gagtaatata cctagaatac caaagacgaa tacaattgca atggaaccaa
    18901 tttttccttt atataaaaga taaaatgatg ctataaatgc aattattcca tataaatccc
    18961 aattaacttc tttggcagat gaaaaagctg ctgataatat gaatcctaga gtaattggtc
    19021 taagaactgt caataagttt tctacctttt tattattttt aaatttagaa aataactttg
    19081 atataatagt tagacctatt aatgcaaaaa ttgtaacacc aatagttgca gctagagaac
    19141 caaagaagcc agcagtctta aatcctacaa atgtagcact atttattgct acaggacctg
    19201 gtgtagattg tgatatagca agtaaatcca aaaactcttg attagttata aagtgatatt
    19261 tagatataaa ttcttgctgg ataaatggta gcatggcata accgccacca aaactaaatg
    19321 cccctatttt aaggaatatt aagaagagta gtattatttc tgacatagac tatatacacc
    19381 tcctccaatt attaaataaa tagggcttat attgaataca ccaacagata aaactgctat
    19441 aattaatagt agtatgttag ttttagactt tggtagtttc ttgaacatgc tcgtaaaaga
    19501 atacaatata agagctatta caacaggcgc aactccttta aaaaatccat ctaaaatttt
    19561 agatgatgaa tttttaaagt atagatacga taagactaag actatacaaa atgatggtaa
    19621 agcagagcct aaggtacata taagaactcc tggtatacca taaagtttat atcctaataa
    19681 tacagatata ttaactgcca gtactccagg ataactttga gctatggata aataatcaat
    19741 aaattcttcc tgctctaaaa gtttttgttt gtttacaagt tcatcttgta taagaggaac
    19801 catagcgtat ccaccaccaa atgtaaacgc accaattttt aaaaaggtta aaaacaattt
    19861 caacataata gaaacctcca aaagataaat aacatctaag tatactaata ttaatattat
    19921 atcataataa aaagataata tagtatgata gtattctaag aatttatcat taatgttgaa
    19981 aattaacttg ttcaaatata taatattaaa agcaaagcaa ttagactaga aaaggagtaa
    20041 tgttgatgga acaaaattat actaaaatag atcatgaatt accattaatt cctctaagag
    20101 gattagctat atttccatat atgatattaa attttgatat aggtagagag atatctctta
    20161 aagctttaga ccaagctatg atggatgaag aacttatatt tttaacttct cagaaagaag
    20221 cagaggtaga tgagccagga gaagaggatt tttatcatgt gggaacaatc tgtaaagtta
    20281 agcaaatgat aaaattacca ggagatacag ttcgtgtttt ggttgaaggt gtatcaaggg
    20341 gtagagtaaa gaaaatagaa caagaagatg ggtatttcag agcagtaata gaagaaatag
    20401 tatttaatag tgataatttg gatagtgaaa cagaagttga aattgaagca tttgtaagaa
    20461 atgtatttga tgcctttgaa gagtatataa atattggaaa tagggtatca ccagaaatat
    20521 taatatctct agctgatata gaagatgtag atagatttat agatacgata gctgcaaaca
    20581 tatatctaaa atcaagccaa aaacaagaaa tattagaaga atttgatatt agaaaaagac
    20641 ttgaacttat ttattctata ttattagagg aaatagatat attaaaaata gaaaagaaaa
    20701 taactttaag agtaaaaaaa cagatgaata aggttcaaaa agaatattat cttagagaac
    20761 aattaaaagc tatacagaaa gaattaggtg aagaagaaga tataaattct gaagcagatg
    20821 agtatagaga aaagcttaaa aaaataaaag cacctaagac aaccaaagaa aaaatagaaa
    20881 aagagataga taaattttca aaaatatctt ctatgtctcc agatgtatct gtaagtagaa
    20941 actatttaga tactatattc tcattgccat ggaataaaga gacaaaagat aaattagata
    21001 taactaaggc aaaagatata ttagatgaag accattatgg attagaaaaa gttaaggaga
    21061 gaatactaga gtatctagct ataagaactc ttgctaagtc acttaaaggg cctataatat
    21121 gtctagttgg tcctccagga acaggaaaga catctatagt aaaatcaatc gccagagcat
    21181 taaatagaaa atttgtaaga atatctttgg gtggagttag agatgaagca gaaataagag
    21241 gtcatagaag aacttatgta ggttcaattc caggaagaat aattaatggg gtaaaagaag
    21301 cccaaacaaa aaatcctgta ttcttatttg atgagataga taagatggca gcagattata
    21361 aaggtgaccc agcttcagca atgttagaag tattagaccc agagcaaaat aaggactttg
    21421 tggaccatta cttagaaata ccttttgatt tatcaaaaat actatttgtt acaacagcaa
    21481 atagtctagg taatatacca agaccattat tagatagaat ggaagtaata gaagtatctg
    21541 ggtatataga agaagaaaaa ttaaatatag caagaaaata cctacttcca aaacagatta
    21601 aagaacatgc tttaaaagaa aactttataa aaatagatga tgaaacttta agaagtataa
    21661 ttaaccatta tacaagagaa gctggtgtaa gaacactaga aagaactatt ggtaagattt
    21721 gtagaaaggt tgccaaaaaa tacgttgaag acccaactct tgaagaggtt gttataaata
    21781 agtctgacct agagacatat cttggaaaag acatgtttaa gtatcaactt gcagaagtta
    21841 atcctcaaat aggattagta aatggtcttg catggacagc agttggtgga gttacacttg
    21901 aagtagaagt aaacgtactt aaaggtaaag gagaaattgt attaactgga aaattaggag
    21961 atgttatgaa ggaatctgcg aagacaggta tctcttatat aaggtcaata gtggacaagt
    22021 ttgatataga ccctgaattt tataagacga atgatattca tatacacatt ccagaaggcg
    22081 ctgttccaaa agatggacca tcagctggta taactatggc tcttgcagta atctcagcac
    22141 ttactaaaag acctgttcct ggaaatatag caatgacagg agagataact ttaagaggta
    22201 gagtcttagc agtaggaggg gttaaagaaa agttattagc agctcataga gctggtataa
    22261 caaaagtatt aattcctaaa gaatgtgaag ctgatttaga tgaaatacca gaaaatgtaa
    22321 aagaaaaaat ggagtttgtg cttgtagaac atatggatga agtattagaa caagctttat
    22381 taaagagtgg tgaaaataat gaaaattaga agttcagaga taactatgag tgctgtgaat
    22441 aaatcacagt atccagcaga aggaatccca gagatagcat tggctggtag gtcaaatgtt
    22501 ggaaaatcat caataataaa tacattgctt aacagaagaa acttcgctag aaccagtcaa
    22561 acaccaggaa aaactagaac tataaatttt tatctaataa ataatgaatt ttattttgta
    22621 gaccttccag gctatggata tgcaaagata gctaagtctg aaaaagaaaa gtggggaggt
    22681 ataatggaaa gatatctaga aagtagacaa gagttatgtt ctatattcct acttgtagat
    22741 attagacatg agcctacagc agatgataag cttatgtatg aatggataaa gcactttgga
    22801 tataactgtg tagttattgc aactaaggca gataaaatat ctagaggaca atatcaaaaa
    22861 cacataagta taataagaaa aaaattgcaa atggaaagta gtgaaaaagt aattcctgtt
    22921 tcttcactaa aaaagactgg tgttgaagaa ttatgggaag agattgtaaa tcaatacaat
    22981 caacatggat atgaaataac agtagattaa atttaaaatg ttaaatattg acataagatt
    23041 tatttgaata ataaatgtaa taatagttag ttttaattat attaatatta aagcaaaata
    23101 taggatgcct taaaatagtt ttaatgaact ttttttggca tccttattgt ttataaacaa
    23161 taaatatcag taattttgct aaatactaat aaattttagt aaggtatggg aaaattagta
    23221 taaattagtt caactaaaaa attattgact tatgtagtca gcaataaata gcatttaaga
    23281 aatagattta tctgtttttc tcataaagaa aacagttagt ataagcccta taaaacatac
    23341 tgatgctgca atccaataag actgattgct agctataaca taggctgatg tgtgactttt
    23401 aaacttttga ttgtatgtaa gactttgtgc aaaaaaacta ctaaaaaatg ctgttccaag
    23461 agcaaatgat aaattacgaa tagttgcaag aaaactgcct ccgtacccct gtttttgagg
    23521 aggaacatct gctaaaatac tactattgtt tggtgaacta aatgctccta gcccaagtcc
    23581 aaaaataact aaacatacaa ttaaaagata caatggagaa tctgctttta aaagtgccat
    23641 tccaactagt gagatggtca taaatgaaaa agatgctgtt agaatgtttt ttgcaccgtg
    23701 tttatcagaa agtgaacctg caataggtgc tataagtacc ataataagtg gatgtacagt
    23761 cattacataa ccagccatca taggagataa attttttaat tgttctaaat aaaatggaag
    23821 tagaaaagat actgccattt gaggaaaata acaagctact ccaatgatat tgcctacagt
    23881 aaagtttcta tttttaaata gaggtaggtc aataaagctt tgttcaaatt ttacttctct
    23941 taatgccaac aataagaaga ttataagtgc tgttatacct aaatacaatc ttgtattacc
    24001 cttctcattc attgcaagta atataagcgt agtgcaagat gcgaaaagta gaagacctga
    24061 aatatcaaag ctcttgtttt gttcatccaa aacaggttta ggcagaaatt taatgccaag
    24121 aaagactgct ataataccaa taggtatatt gataataaaa atagaaggcc atccaaaatg
    24181 ttctaaaatt atacctccaa ttacaggacc actcatattt cctataccaa ctacagctcc
    24241 agtgattcct atagcttttc ctttttcatt tgctggaaat gcattggaaa ctataccaag
    24301 cccagtagcc attaaaatac ttgctccaac tgcctgaaag attcttgaag aaattaatgt
    24361 tgataaattg tttgacatac tacacagaaa agaacctatt gtaaatataa aaaatcctaa
    24421 tgcgtataga cgatttgaac ctactttatc accaagtttt ccgaaaaata acatagtagc
    24481 tgttacaaca agcatataag ctgttacaac ccactgaatt tgtgacatgt taattttaaa
    24541 gtcagcagca attgtaggat ttgcgatatt tagtatactt ccatcaagag tagacataaa
    24601 tacaccaata cagatgataa tcaatactat ccatttttgt ttcatgataa cactccaatc
    24661 ttaatagatt ttataagtac gatataattg taaaataaac aacaaaaaaa gcacctgtat
    24721 attaggtacc ttgaatgtgt ctaatttcat gaataaatac ggtagttgaa ggatttgtat
    24781 agattactca tgtaaaatta cataaaggta ctcatatact attttcttct accatccaga
    24841 ttttactgtc ggctttggaa tatgaccaaa ttatgccata aggctcgcgg gcttttaccg
    24901 ccgataggga atttcacccg tttatgaaga aaaacagatg tattttgtaa tattatttta
    24961 acataaaatt ataatggaaa caattggatt taagtaatat ccagctgtat tacaatacaa
    25021 atatttcaat atggacactt aaattgtatt tatagataga ataaggtaca gtatgagaat
    25081 ctataataat tagataaaat taatatgtta ttagtattag atggtaagtt ttaaatttgt
    25141 caaaatcaga aagctgtaat aaaattctta taatatgaat atcttaatta agagatattg
    25201 taaattatga ggaggcgcta atatggaagg aaaggtaaag aaggcattcc caggtggaaa
    25261 tacatcacaa ggctcatatt ctttttttga ctatataatt cctgaaaatg taaaaagagt
    25321 tttttgttta aagggtggac ctggagtagg aaaatcctca cttatgaaaa aaatttataa
    25381 agagtttttg catagaggat atgatattga tttatatcat tgtccttctg acccaagttc
    25441 gttggatggt ttagttataa agaaattagg cgtggtactt atggatgcaa ctgccccaca
    25501 tactatggac ccaaagctac ctggagcttt ggatgagata attaatttag gtgattactg
    25561 gaatacagaa gaattagaaa agaataaaca agaaatatca gtttatgata aagatattag
    25621 taattcattt aaaagagcat ttaagttttt aaagtcagca gaaccaattt ttagagacat
    25681 agaagaaaaa tattctgatt gtatggatta tggcaaagta aatttggtca cagaagaatt
    25741 tataaaaagg ttatttgatg gagttaaaag cacaggaaat ctaaaaagag aaaagcattt
    25801 atttggttca gctataactc ctgtagggtg tttagattat acagaaaaca ttttaaaaga
    25861 tgtaaagaaa gtctattatt tagatggaga aataggaact gggaaaacta cattattaaa
    25921 caaagtatat aagaaagcta ctgaaaaagg tttaaatgta gaagtttatc attatccact
    25981 tattccagag aaaattgaaa ctgtactatt aactgattta gatataggca taactataag
    26041 tacgactttt aaagaagaag atacaattga tttaaatcag tttttaaata gagaaaaact
    26101 acttaaatat gaagaagata ttaaatttga tgaaaaagtt ttagatgatt taatttgttg
    26161 ggcagtacta aatcttaaga gagccaagtc taaacatgat attatagaaa gttactatag
    26221 tcctaatatg agatttgatg aagtagggaa attaagagat aagttaatta aaagaatttt
    26281 aaaatatgag gaaaacttat aaacgtatat gtttaaaatt aatgttaata ataatataat
    26341 ttttagtaaa ttggtgtagc tttgaggcta tgccatttta cttttttttg ctaaaaaatg
    26401 atattaataa tctccaaagc cattatttgt ttttcataat tattatttcc tttcctaatt
    26461 tatgtttttt tataatatca caacaatgtt tattgaaagt ttatataatt ttaagaacat
    26521 ctaaaaatgc atacttgata ttggtaaatt agtgatagga gttcaatgta tgatattata
    26581 tactaaagat gaattttaat atataacttt gatataataa gcatatgtaa atgtttaata
    26641 tttaattaaa gaaaattatc atataaaaat aaatttgtaa ggagcaatac agtatgaaaa
    26701 aacaatatgt gtttataata ctagcaagta ctattttagg tatacttgtt ggaaccatat
    26761 ttagagatta tagcaatgaa gaaacagttt atacaagcaa agacaagtca ataagaaaag
    26821 aaataaaaat gacaagaaaa tctataaaag aattaaccaa agagaaagac aagttagata
    26881 aagaaattaa ttcaatgaaa caaaatcaaa aaaattctga agaaatatca gaaatagaaa
    26941 cacttagaga tagtctatca tattcagatg taaagggtag tgggataata ttaagtatag
    27001 atgctataga tgaaaaaaca gggaatatag ctaatagtat agactataat aagattcttg
    27061 taaaagttat aaatgaatta aaagtaaacg gaggaaaata catagaaata aatggtcaaa
    27121 gaattaatca atattcagaa gttgtacttg caggaagcca tataaatata aatggagttc
    27181 ctgtagcaca accatatgaa ataaagtgca ttggagataa ggagaaatta tctaattatg
    27241 tagataaagg tagtaaatat ttagatagca tacaaaccaa ttatccaatg aaaataagca
    27301 taaaaactga agaaaatatc tctatgaaaa aaatgaatat acctaataaa ttaaagtata
    27361 taaagggtga ttaatattat attagaggaa agcagtttgc caatgttaat accagaaaaa
    27421 cttgcaaaga aatataatgt atttccagtt gagtttcaag atgataattt agttgtagaa
    27481 atagaagatg aggatattta tgctctacag gacttgagat tagctacagg taaagaaatt
    27541 atattgaaga aggagaaaaa agaacttata agtgaaaaga ttgaaaaata ttataatagc
    27601 tttgaacttg atgaggatta tgcaaaaaaa ttatttgaaa atcttttaga aaaagctata
    27661 aaagaaaatg caagtgatat acatatagaa ccatttaaag aacatttaat agtgagaatg
    27721 agggtagatg gagaactaaa ggaagtatca aagtttttag ttgatgtcta tccatcattg
    27781 tctacggtta taaaattaaa ggcatcaatg gatataacag aaaaaaggct tcctcaggat
    27841 ggtagggtgg atataaagtt aggtggaaat ttaattgaca ttagagtttc atcaatacca
    27901 actgtctatg gtgaaaaaat agttttgagg atacttaata gagatacttt tttaaaagac
    27961 aaattagaac ttggtttttc agaggaagct ataaaatcta taaatcgtat aataaataaa
    28021 agagcaggag tattattagt gacaggtcct acaggtagtg gaaagactac aacagtatat
    28081 tccttattaa atgatttaaa aggaataaat aaaaatatta tgactataga aaatcctgta
    28141 gagtataaga tggatggcat aagtcagatt caagtaaatt caaaagtagg gttgagcttt
    28201 gatgtaggtc ttagagcgat attaagacaa gacccagata taataatggt cggagaaata
    28261 agagatgcag aaacagctaa gatagcagta agagcagcta taacaggtca tttagttata
    28321 agtactttac atactaatga tgcagtatct tccatagcta gattactaga aatgcaaata
    28381 ccaccatatc ttttaaatgc ctctcttata ggtgttatat ctcaaaagtt ggttagaaaa
    28441 gtttgtaatc attgtagcca tgagattatg ataaaagata attttagtgg agatgtaaat
    28501 actaaggtag ctgtagggtg tgaaaaatgt aatgataaag gatactttgg aagaacagca
    28561 atttatgaaa tcttagaaat taatgatgat ataaagacat gtataagaaa tatggaggat
    28621 tctagtacta ttaaagatgt ggcacaaaat aatggaatga taacatttga agatagctgt
    28681 aaaagactaa taaatgaaaa aataacgaca ttagaagagt gtttagtagt aaatgaaatg
    28741 atttaactga attgtatagt taaacttcgt ttggtcagtt gtctttattt aatctatttt
    28801 aattaagatg tttgagtata aattatattt aagtgaaata aaattaaatg cattaaatta
    28861 gaaaatatta agtttattta attgtaatta atataatttg gaaggtatta tagtacatga
    28921 gattatctaa aaatatattt tataatttag aaaagtttta tttagtatta aatagaatca
    28981 gtgataaaga aattagagta atttgcaaag agataggcat attgctggaa tctggatgtg
    29041 aaattacaaa aatatttgaa atcattgaga gtcagtcaag taaaaaagta aagaatttgc
    29101 ttagtatagt atcaaatcat attcaaaaag gtaactcaat agcagaatca tttcaaataa
    29161 caggtatatt ttctaaattc tttataagta tgataaaagc aggagaaact agtggaaact
    29221 tagatataat aatgagtgat ttatctaatt attatgataa agaatacaaa ttaaaaatga
    29281 aaataataac tatttcaata tatccaataa tacttataat attatctatc ttatcaatgt
    29341 tgtttatatt cgtatttgta atacctaatt ttcaggtggt ttttaccaac aatggaattg
    29401 aaccaccttt aataactaga gttttaatgg gaatatctac agtggttaca aataacttag
    29461 cttatataat atttagtttt atattgtttt caataggaag catttatttc tttataacaa
    29521 atgataatat aaaaaaattg attaattcgt taaaattcaa aatacctttt ataaaaaaaa
    29581 ttaatcagtt agtagctaca acaagatttt caagggcatt gtccgtttta attagcagtg
    29641 gaatacaaat tgtggaagct atagacatgt cagctagtgt tatagacaac gaatttattt
    29701 atgaaaggtt aaagatttct aataattata taaaaaaagg aaatagcata ggtaaatctt
    29761 tgaatttagc aaatgttttt ccaaaattat ttatttcaat ggcaaataca ggagaagaaa
    29821 gtgggaaact agataaaagt ctaaatgtaa taaataaatt ttatgaaaat gaattaaata
    29881 acaaaataga gcaaataatg aaatttatag aacctatgct aattgtattt atgggattaa
    29941 ttattggcac ttttatttta gcaatggttg ttcctatgtt tgatgcaatt actaattttt
    30001 agagagaaaa ataaatttta ttagatgaaa cttttgaaaa ggagagaata tttaattgat
    30061 aaatttgata aataaaaaac gaaaaggatt tacacttgtt gaaatgattg tagtagtaac
    30121 tattttaggc gttatatcta gtatagcatt agttaagtat agtaaggttc aagaaagtgc
    30181 caaattaaat gcagactata cgaatgctgc taatatagta actgcagcta gcatggcaat
    30241 taatgatgat gaaaagacaa tagactctct aagtgtagaa acattgaagg aaaagggata
    30301 cctaaatact gttccagttc ctcagagtac atcaggtaaa ttcgaacttg tcataaatga
    30361 tagcggaaca gatataagcg taaatataaa ttctaaacaa ttttatccaa aataatattt
    30421 tatattgatt gctgtaagtt ttaaaattat ttttatttaa gaaggagatg gctataatta
    30481 aaaaaattct aaacttagaa ataaatgatg attatataag gcttgtattt ttaagaaaaa
    30541 gtcataaaaa agtttttata gataaatcaa ttataaaaga gattaacttt gatataaaaa
    30601 atgatagtaa ttcgattgag aagattaaat atatagaaga tgtagttaga tttgtaaaag
    30661 aggagattgg taaatcaaaa atattatata aaaatttata ctttaacatt caaattcaag
    30721 atatagtcat tagaaatgtt gaagttctaa atactaagaa aaaaagagac atattaagca
    30781 tgattgaatt tgaaataaca caatacattc caataaacat aaataactat tcaataaaat
    30841 ataaagttat aaattctaaa aatgataaat tgaatataca agtaattctt ttcccaaaga
    30901 gtattattca attaattaag aacatttcag aaaatctaaa tatgaatcca aagactataa
    30961 atataaattt tgatatatta caaaagctta taaacttaaa tttaatagag aatttttcag
    31021 aagaaggggt atttatagaa tgtaaaaaaa gtcagttaat tataaatata acaaaagata
    31081 aaaaaataag agaaacatac ttgctatcaa aagagggaaa atcatatgag ttcataaaaa
    31141 gattattaag ggattttaag tatgtttatt actatggtat agaaaattgt tttattgaag
    31201 aatactttaa atatacagat aaatctattg aagtaaatcc attaagatta aaagataaag
    31261 taaaagtaga aaataatttt gatgcagatt tagaagacaa taggataaat tatataaata
    31321 gtataggaat gattatttaa gtgaaagtgg ataaaacaat aaattttctt aatggattta
    31381 aaaaaactaa accatgtaat aaaatctata aaataataat agtcttaatt ttaacgtgta
    31441 ttttatttaa atcatttatg tatgtgaaat ctataaatga acttgaagat tatataaatc
    31501 aaaataagct agtggataaa tcaaagcaca ctttaccaac aacagataaa actagagaga
    31561 aattttctaa aataaaactt aatgaaataa aaaaaatata tgaaacaatt ggaataaata
    31621 gtattactaa aatatcgata gataaaaata agctagagat ggaaggtgtg tgtagtgatt
    31681 tagatgtttt aaacaaccta aggaaaataa agtacataaa atattattac atagacagta
    31741 ttgtaagaga tggagaatat tatagattta gaataaaaag ttagataggt gattattttt
    31801 gagattaaat aatagagaaa aaaatctact taaaatattg ttaatattag ttattatatt
    31861 ggcaagtgat atagcagtaa gttatttgga agaaaaccta actagtttga agaatgaaaa
    31921 gcaaaatata ataaataaaa taaataatca agataattat caaataaagg ataataagca
    31981 tatagatgat aaatatatag aaagtgttga attaaataaa aatgaagaat tgaaaaataa
    32041 ttttaataac tcatttttag ataaaaaaac aaataaagat atagtgttat tagtagaaaa
    32101 tgaactgaga gatattgtga atgtagaata tattaatcaa gaaagtagtt tagataatca
    32161 caataaaaaa caagttaatt tagaaataaa agttaatgga gaacttgcaa atgtgttgaa
    32221 acttgaaggt gtaatgaaga agttaagact aaataataaa cttgaaaaga tagaaattaa
    32281 caaattaaaa gtcaataatt ttgatgttca aaatattcca aatgaatata aacaagaaaa
    32341 agacaatatt gttgaatgta aaatgacagt tagagtcata taacaaaaaa gaatagataa
    32401 agtaaaaaac tattatcaat taataaaatt ttatagagga attagtttta cgataattca
    32461 tttctacaag agggattgtt gatgatttta tcgaaatcct aattaaagtt aatatattgt
    32521 accaaaatat aagtgaattt aatagaatat ttacttatac tatagattga ttaataaaaa
    32581 aatggtataa taacaaattg tactttaatt taataataag ggagtggaag tcatattgtt
    32641 agggagaaat gagctatgcc cttgtggaag tggcaaaaaa tacaagaaat gttgtttaaa
    32701 taaagatatt gtttcagaaa gagcatgcag aaaaactgaa ctttcacaaa aacaatatac
    32761 agatttatat tcaaagttat atgattattc aagacaggat aagtttaaag aagaatgtga
    32821 aaaagctaaa gaaatgtttt atataatgca aaatgatagt gtaaatgaaa aatttgaaag
    32881 attttttaat acttatttaa tacaagacca cataatggaa aataaaaagg ttatgacagt
    32941 tggttttctt gaagaaaatg gtgcaaacct aagtcaatca gaagtatcaa tattaaaaag
    33001 tatgtttgaa tcatacgtaa gtatttatga ggtaaaagaa gtttctgctg gaaaaatagt
    33061 attaaaggac tgtttaagtg gaaatgaact ttgtacagaa gatgtaaaac ttctgagaag
    33121 ttttaaaatc ggaagttgta tgatagctag aatagttgat attgaaggaa ctaacatatt
    33181 gatagatata actataagta tatcaaatga ggttaaagat ataattttaa aggatattat
    33241 gaatctattc aatcaatatc aagatgtata caaagatatg aagtcgttct taatttatca
    33301 tacacatata ctatacaagt atatacaaca gcttttagac ccaagtatag ctgaatattt
    33361 aaagagagaa agagataaaa acgatacaaa agttaattca gaaaatgaat tagctgaaga
    33421 agaatgtaaa gttttagata ctcttaaaga aaatgtagaa aaagaaaata tagatgcatg
    33481 tatagagttt tggaatgaat ataagaaaaa tcatgaaaat ataaaaggag ctgaaaatgg
    33541 ttgggcagct gctgttgaat actatgttaa aaaagaagca ggacaaccta taactcaagt
    33601 tcaaatatca aagaaatacg atataagctc tagtacacta ggaaagagat acaaagattt
    33661 aaaaatatct taattaatta taaaaagctt taagtcatag ataaagaatc tatagtataa
    33721 tatatgtata atgtttagaa agaggtatta ataatgagtc ttagtttagg aaatgcaatt
    33781 gctgtatcaa cgaactttat aaaatctaac ccagctgtac ctgtgtacaa cggagaagaa
    33841 atatatgcag ttatttatca tatagaaata ggatataata atggtgtatc acctgatacc
    33901 aaacaatata taataataga ctataaagag tttgatttat ctatggataa aaaaaatgaa
    33961 ctaataaatg ttgctaaaga gtactgtaaa tctaaaggta ttgtagaaaa cgaaaacctt
    34021 gaaataaacc ttttagacaa tgaagaagca gagaacttct tagaaaaggt gtttaataac
    34081 atgaaggtta taagaggtct tataactaaa aaaggataaa taaatggact atataggaat
    34141 agaaaatata acaccttatg aaaatacata tgaatttagt gtatatgaat atgatgatga
    34201 aatcacctta ggtagtgaaa agttatatgt gtgtgaatta agggttgtat tgattaaagt
    34261 taattctctg tatgttgaaa gattgcataa atcagttgaa gcaatggtct tagtaaaaaa
    34321 cttgaaaaag gatttagata aaacacttgt tgtaaacaaa ataaagaatt ttgtgctaga
    34381 tgagatttgg gtagaaaatc tagtaaaaga gaatatagaa gttatatttg tagaaagcta
    34441 ggaataaccc tagctttttt atattacaat ctaagagagg aaaacaatat gttaagagta
    34501 tctaatgtaa aacttggaat tgataaagat atatctttat taaaagatgt tgtacttaag
    34561 aagctaaaaa taaaagaaaa aaacttagtc aaatatagta tatataaaga atctatagat
    34621 gctagaaaaa aaggaaaaat ggaatttgtt tattctgtag atgtagaagt caaagatgaa
    34681 aataaaatac ttaactcaaa aataaaagat gtaacaaaaa taaaggaaat cagatacata
    34741 aatgtacctg tgggtgataa aaaattaaag aataatcctt tggtaattgg tagtggacca
    34801 gctggtttat ttgcaggtct gcttttagct caaatgggtt atgaaccaat catacttgaa
    34861 agaggtcttg atgtagacag tagaaccaaa gatataagtg atttttggac aactagaaaa
    34921 ttaaaaaata attcaaacgt tcaatttgga gaaggtggag caggaacttt ttcggatggt
    34981 aaacttacaa ctagaataaa agatatacga tgtagaaaag tattagaaga gttagttcag
    35041 tttggagcac cagatgaaat attatactca cataagccac atgttggaac agatatatta
    35101 aaaaatgtag ttaaaaatat aagaaatgaa ataataagtt taggtggtca agttagattt
    35161 aattcaaaag taacagatat agttgtatca aatgattcta tacaatctgt aataataaat
    35221 gatactgaaa aaatagatac agatacaatt atactagctg ttggacatag tgcaagagat
    35281 acttatgaaa tgttgtattc aagaggtata aaaatagttc aaaaaccttt tgcaatagga
    35341 gctagagttg aacatccaca agatttaata aataaagcac agtacaagga tttttataat
    35401 catcctaggt taggagctgc agattataga cttatagagc atgtttcaaa tggaagaaca
    35461 gcatatactt tttgtatgtg tccaggaggt agtgtcatag catctgcatc aaatgatttt
    35521 gaaatagtta caaatggtat gagtgaacat gcaagagata aaataaatgc aaatagtgca
    35581 tttttagtaa atgtaacgcc agaagatttt aagagtgata atccactagc aggtgttcat
    35641 ttccagcaga agtatgaaaa attagctttt gaattaggtg gaaaaaatta caatgcacca
    35701 gttcagcttg ttggagattt tataaacaat aagacttctt tgaatttagg aagtgttgag
    35761 ccatcatata gaccaggata tacacttaca aatttaagtg aatgtttgcc tagcttcgta
    35821 acagagacta tgagagaagc gtttatatct cttgataaaa aattgaatgg gtttgcaatg
    35881 tatgatgctg ttttgacggg agtagaaact aggtcatcat caccaataag aatagtaaga
    35941 gatgaaaata ctttagaatc agtgagtatt aagaatctat atccatgtgg tgaaggcgct
    36001 ggatatgcag gtggtatagt tacagcagca gttgatggta taaaatgtgc agaaaaaata
    36061 atacaaaaat acaccaataa tacaaaaatt taacataaac ttaatgattt tttaatattt
    36121 aacatgaatt taacattatc actcctataa tttgataaaa tacaataggt tataaaattt
    36181 ttagatacag taatctcttt acaaggagga aataatttga acattataat aagtctaatg
    36241 ggtggattag gtctgttctt atatggtatg aaccttatgg gagaaggtct tcaaaaatct
    36301 gctgggacaa agctaaaaaa gataataaaa ctacttacta gtaacctatt tatgggagtt
    36361 ttggtaggta caggagttac agcagtaata caaagttcaa gtgctactac tgtaatggtt
    36421 gttggtttcg taaatgcagg aataatgact ttaaaacagg caataggagt tataatgggt
    36481 gctaatatag ggactactgt tacagcccaa ttggtatctt tcgacttaac tggtatggcc
    36541 ccagtagcat taggtgtagg tattatactt tatttatttg gaaataagcc tagaataaaa
    36601 aatatagccg aaatacttat aggttttggt atattattta caggtatgga ttttatgaag
    36661 atggcagtgg agccactaag agactatcaa ggatttactg acctacttgt tacatttggt
    36721 agatatccac tacttggatt attattggga tttgggatta cagcaataat acaaagttca
    36781 agtgcatcta tgggtatgtt ggttgcactg gcagcagaag gtctagtgcc attatcagca
    36841 gcactgccaa ttctttatgg ccaaaatatt ggtacatgtg taacttcact gttatcaagt
    36901 attggtgcta acaaaaatgc acgaagagca gctatgatgc atctaatctt caatgtttta
    36961 ggaacggtga tattcttaat attcttgaat aaaccagtag taagcatggt tacaagttgg
    37021 gatccaagca atgttgcaag acaaatagcc aatacacata cattgtttaa tataatatct
    37081 gtattgatac ttttaccatt tacaaatctt attataaaac tagctataaa gcttgttcct
    37141 gatagagcag gtgatataga tgaagatgaa actaaaacta ttaaatatat agatgataga
    37201 atgatagaaa ctccttctat agctcttgca aatacgataa aagaagcact tcgtatgggt
    37261 gagaaggcga aggaaagcct aaatgcatct atggaagcct tagtagaaca ttcaactgaa
    37321 aaaatagcta agacatatag acgagagaga ttaatcaatg atttacagaa agctatttta
    37381 aattacttac ttaaactttc aaaagcacct ttagatgatg attcaagaga agttgtggat
    37441 actttgttta atacagtcaa tgatatagaa agaattggtg accacgctaa aaatatagct
    37501 gaattatcgc aagttgcaat agattcaaat atttctttct cagaagaagg acaatctgaa
    37561 cttgatgtta tgtataatag agttgtttca gcatatactt atgcattaga atcaatgaga
    37621 actgataatg ttgatttagc ttgtaaggtt ataaaaattg aagaacaagt tgatataatg
    37681 gagaaatctt gtagagctaa tcacatgtat agattgaaca ataatctatg tagtatagaa
    37741 aatggagtta tttatttaga cgtaataagt aatttagaga gaatatctga ccatgctgtc
    37801 aatatagcac aacaagttat agcgaagaga ttaggaaatg attaaaaata attaatttaa
    37861 aataatataa aatttaaaat agaggataaa taaaagagaa actttaaatg atacgtttag
    37921 agtttctttt tttgtaaatt tatttgacta aaatttttaa atttatacat agttatagta
    37981 tttagaagaa tcgatttcct gataataaat gatgagatat gtatgatttt gtggcaaact
    38041 tttaaaaaaa acacctatat tttgtgttat aatctcttta aaacgaatat gctgaaaaga
    38101 gggatttaaa tgggaaaaat aaattttgat tatagtaaag ctacagagtt tttttgtcaa
    38161 aacgaaatag atgtcatgca accatatgta gatgttgcgc acgacatgtt acataataaa
    38221 actggtttag gaaatacttt tttaggatgg atagaccttc ctaaaaatta tgataaagaa
    38281 gagtttgaca gaataaaaaa atctgctgag aagataaaat cagactcaga tgttcttctg
    38341 gtaataggta taggaggctc ttatttaggt tcgagagctg ctatagatat ggtaagtcat
    38401 tcttttagga atggacttaa aaaagagcaa agaaaggctc cagaagtata ttttgtaggg
    38461 cataatataa gctcaacata tattatggat ttattagata taattgaagg aaaggatatt
    38521 tctgtaaatg taatatctaa atcaggaact actacagaac cagctctggc ttttagaata
    38581 tttaaagatt acttagagaa aaagtatggt aaggaagaag caagaaagag aatttatgca
    38641 acaacagatg caagtaaagg tgcacttaga cagttagcta cagaagaagg atatgagact
    38701 tttgtaatac cagatgatgt aggtggtcgt ttttctgtat tgacagcagt tgggttactt
    38761 cctattgctg ctgctggact tgatattgat gctatgatga aaggcgcaaa tgatgctaga
    38821 gaagcatttc aaaatcctga cttaaaaagt aatgatagtt atagatatgc tgttgctaga
    38881 acaattttac atagaaaagg aaaagatgta gagttattag tgaactatga acctcaacta
    38941 cattatgtaa gtgagtggtg gaaacagctt tatggagaaa gtgaaggaaa agaaaataaa
    39001 ggtttattcc ctgcttctgt agatttctca acagatttac attctatggg tcaatacata
    39061 caagatggaa aaaggctttt atttgagaca gtacttaatg ttgaaaactg taagagaaat
    39121 ataactataa gttcagagga agtagactta gatggtttaa attatttagc aggtaagact
    39181 gtagattttg taaatcataa agcttttgaa ggaactctat tggctcatac agatggaaaa
    39241 gtacctaatt tagtaataaa tatacctcaa ctagatgagt ataattttgg atatttagtt
    39301 tatttctttg agaaggcttg tggaataagt ggatatttat tgggagttaa tccatttgac
    39361 caaccaggag tagaagctta caagaaaaat atgtttgctt tactaggcaa accaggttat
    39421 gaaaaagaaa aggaagagct agaaaaaaga cttaaataat tttaaatagt taaggtttaa
    39481 ttaagattaa aataatataa tgaaatcatc gaaaaggagt ttactcaaaa tagatgattt
    39541 catttttttt atgaaaaatt gggaaaaata tattttgata atttatatta tattaagata
    39601 gggagtggta tgagatgtca agaagaaaga aagggataag tttagtaata ttagttgcta
    39661 taataagttc aatacttagt agttttctaa caataatttt agttaaggac aatttagtaa
    39721 gcaaatctac aggaagttct acgccgatag ttgtaaatga tgatggtaag agtcaaaata
    39781 tttatcaagc agttgcagaa aaagctacgc catctgttgt aggtattaca acaactagtg
    39841 ttgatactag taatatgttt gcaataccaa ctgaaacaca aggtgtagga actggaatca
    39901 tagttgattc aaatggatat atacttacta attctcatgt tatatcagat ggtcaagcta
    39961 caagtgtaaa tgtattattc aatgatggtt caacaacttc aggtaaagta gtatggtttg
    40021 accaacaact tgatttagct atagttaagg ttgataaaac tggactaaca ccagcagaat
    40081 ttgctgatag tgacaaagta aaagttggag atatatcaat agcaataggt aatcctcttg
    40141 gattagattt tcaaaaaaca gttactcaag ggataataag tggattagat agaactatac
    40201 aaacagaaaa aactaatatg actggtttat tacaaactga tgcaagtata aatgcaggaa
    40261 atagtggagg accattgtta aatcaaaaag gtcaagtaat tggtataaac acagcaaaag
    40321 cttctcaagc agaaggatta ggatttgcaa taccaatcaa tacagctaag agtatagttg
    40381 aagaagtaat caaaaatgga aaatatgaaa aagtaacttt aggcataaaa ggtacagatg
    40441 tatcaaatta tgaagcagca acaggtacaa aattaagtac tgataaaggt gtttatgttg
    40501 cagaagtaat atctggttca tcagcagaaa aagctggagt aaaggtaggg gatattataa
    40561 ctaaagtagg agatacagat ataacaggta tgaatgattt aaataaaaag ttgtatactt
    40621 tctcaaaagg tgctagtaca aaaataacag taaatagagg cggaaaagca gtaacaataa
    40681 atgtgaattt ctaaatatga ccagaaagaa ggagactaca tggtaaagtg tagtctctat
    40741 ttttatttaa tttttatagt atatacatct aaattaatta aaatgatgta ttgtttatag
    40801 tttattgcta tattttctta taaaaataaa tttaataaat atttaaattt aatttacaaa
    40861 aacaatataa atatcataat aaaataaaat tttttaatat tactaaaaat atatagacaa
    40921 aataataaca aatatagtat tatgtaattg tagaaatgct tttcataggt atattctatg
    40981 aagatgaatt gcataaaaat gaaaaaatgg aatggatatt atttaggggt gaaaaatcat
    41041 gaatccatta gttataaact tacaaaaatg tagcatacat gatggaccag ggataagaag
    41101 tacagtattt tttaaagggt gtccacttga atgtgtttgg tgtcataatc cagagagtca
    41161 aacatataca aaacaagttt tgtataatga agaaagatgt tcaaaatgtg aagcatgtat
    41221 aaatatatgc cctcataagg caatttacaa aggtgaaaca aaaatatgct tagaccaaga
    41281 taagtgtgag ttttgtgaaa cttgcttaga ctattgtgta aacaatgcaa gagagattgt
    41341 tggtcaagag tattctgtaa gagacttggt taaagagata gagaaggata gaattttcta
    41401 tgaagaatcg ggtggtggag taacactatc aggtggagaa gtaatggctc aagatatgga
    41461 cttcatttgt ggagtaataa acatgtgcaa atcaaaggga atccatgtag caattgatac
    41521 atgtggctat gcaaagtcag aaaattatga aagagttgct aaatgtgcag atttgttttt
    41581 atatgatatt aagcttattg atgaggataa gcacataaaa tttacaggaa aatcaaatga
    41641 cttaatactg aaaaatgtta agattttaag tgaattaggg gttaacataa atataagaat
    41701 accattaatt gtaggagtaa atgtagatga tgaaaattta gaggttaaaa aaatgataga
    41761 gtttttaaag cctttgaata tacaagcagt aagtcttctt ccatatcata atattggtaa
    41821 acacaagtat gataaaattt ataaaaagta tgaaggagaa gaactacaaa gaccatcaga
    41881 agaaaaatta gaggaaataa aaagactgtt tgaagcaagt aatttcaata ctaagattgg
    41941 agggtaataa aatggcaaga ggaacttttg agagaactaa aaaattaaga gaagaaagta
    42001 ttaatgcaga accacacata tctattgaaa gagcagtact tatgacagaa gcttataaaa
    42061 aatatgaggg aagtgtagag attcctgtac ttcgtgcttt atcatttaag cattatattg
    42121 agaatagaac tcttagcata aatgatggag aattaatagt aggtgaaaaa ggtgattctc
    42181 ctaatggagc accaacatat ccagaaattt gttgtcacac aatggaagat ttagaagtaa
    42241 tgcacaatag agatataata aattttagcg tatcagaaga agctagaaaa atacataaag
    42301 aagaaataat tcctttttgg aaaaaaagac aaacaagaga taagataata aatgcaatga
    42361 cacctgagtg gttagcagca tatgaagcag gtatgtttac agagtttatg gaacaaagag
    42421 ccccaggaca tacagtttgt ggagatacaa tatataaaaa aggattttta gatttaaaga
    42481 aagacataga agcaagatta aaagagctag attttcttaa tgatttagat gcatataata
    42541 aaaaagcaga tttagaagct atggcaatag cttgtgatgc aatggttata ttaggtaaaa
    42601 gatatgctga gaaagcaaga caaatggcag aagaagaaac agatgaagct aagaaaaaag
    42661 atttattact aattgctgaa acttgtgatg ttgtaccagc tcacaaacca gaaacttatc
    42721 atcaagctat acaaatgtat tggtttgttc atataggggt tactactgaa cttaatatat
    42781 gggatgcttt tactccagga agacttgacc aacatctaaa tcctttctat gaaagagatg
    42841 tagaaaatgg aatactagat agagatagag cacaagaatt acttgaatgt ttatgggtta
    42901 aatttaacaa tcagccagca ccaccaaaag ttggtataac attaaaagaa agtagcacat
    42961 atacagattt tgcaaatata aacactggtg gaataaatcc agatggtcaa gatggtgtta
    43021 atgaagttag ttatataata cttgatgtta tggatgaaat gaaattgata caacctagtt
    43081 caaatgttca aataagtaaa aagactcctc aaaaattctt aaagagagct tgtgaaatat
    43141 caagaaaagg atggggtcaa ccagcatttt ataatactga agcaatagtt caagagctta
    43201 tggaagctgg aaaaactata gaagatgcaa gacttggtgg aaccagtggt tgtgttgaaa
    43261 ctggatgttt tggtaaagaa gcatatgttc taactggata tatgaacatt ccaaaaatac
    43321 ttgaattaac attaaataat ggatatgacc caattagtaa aaaacaaata ggtattgaaa
    43381 ctggagaccc tagaaatttc caatcttatg aggaactatt tgaagcattt aaaaagcaat
    43441 tacattatat gattgacata aaaatagaag gaaatgctgt gatagaaaat atatgtgcaa
    43501 aacacatgcc ttgtccactt atgtctacaa tagttgatga ttgtatagaa aaaggcaagg
    43561 attaccaaag aggtggagca agatacaaca ctagatatat acaaggtgtt ggtataggaa
    43621 ctataacaga tagtttaaca gcaataaaat ataatgtatt tgataagaaa aaattcgata
    43681 tggatacatt gcttaaagca cttgatgcta attttgaagg atatgaagct atacttaatt
    43741 tagtttcaaa taagactcct aaatatggaa atgatgatga ttatgctgat gaaataatgc
    43801 aagagatatt caatgcatat tacaatgagg taactggtag actaactgtt tgtggtggag
    43861 aatacagagt agatatgtta ccaacaactt gtcatatata ctttggagaa attatgggag
    43921 caagtccaaa tggtagactt tgtgcaaaac cagtttcaga gggaatttca cctgaaaaag
    43981 gtggagatac taatggacct acagcagtta taaaatcttg tgctaagatg gaccacataa
    44041 aaactggtgg aacattatta aatcaaagat ttgcaccatc agtagttcaa ggagaaaaag
    44101 ggttagataa tatggctaat ctagtaagag catactttaa tatggatggt catcatatac
    44161 aatttaatgt atttgataaa aatgtactgt tagaggctca aaagaatcct aaggattata
    44221 aagacttaat agttagagtt gcaggatata gtgaccattt caataattta agtagaacac
    44281 tacaagatga gataatagga agaactgagc aaacattcta ggtttgcttg taaataaaac
    44341 ttcttactat ataaaatcgt aactgatata ataaagtata aatggtttga ttccattttt
    44401 aaaattttag attaattatg agctaacttt ctaaatagga agttagctcg ttaagtttaa
    44461 tgaaaaaatc gttaaattta tatttagtaa atcatacaca tattagtaag taatacatac
    44521 aaaagaataa tttattatag ttataataag gttatatttt ataaaaataa gataatttta
    44581 agcagttaaa ataaagtcaa tttagctact ttaaaataaa actaatagaa aaaaggagat
    44641 ttgatatgaa aactttagga tttattggtt cagggaatat gggaagtgca atgataggtg
    44701 gcatagtaca gtcaggatta gtaaaggcag aagatataac tgtatcagat ttaagccaag
    44761 ttgccttaga taaagtaaaa gaagaatttg gaataaatac tacaactgat tcaaaggtag
    44821 ctgttacaaa ttctgatgtg gtaatagtag cacttaaacc taatatatgc gaaaaggctt
    44881 taactccact taaagaatta atagatgcaa ataaaataat agtatctata gcagcaggta
    44941 aaactataga aagtctggaa agttttatag gttcagataa aaaaatagta agagtaatgc
    45001 ctaatactcc agcccttgtt ggcgagggaa tgtcagctct ttgtaaaaat agtaatgtaa
    45061 cagatgaaga gttaaatatg attaaggctc tgtttgaatc ttttggtgag gcagaaatag
    45121 tatcagaata tttaatggat acagttacag gtattagtgg ttcttctcct gcatatgtat
    45181 ttatgtttat agaagctatg gcagatgcag cagtattagc tggaatgcca agacaacaag
    45241 cttataaatt tgcatctcaa gcagtaatgg ggtcagctaa gatggttctt gaaactggaa
    45301 aacatccagg tgaattaaaa gatatggttt gttctccagc aggaactact atagaagctg
    45361 ttaaggtatt agaagaagaa ggctttagag cagcagttat aaaatctatt gttgcttgta
    45421 tagataagtc taaagatatg agcaaataac agatgtaatt aagtttacta tatggtttct
    45481 tgaattgttt ttttagtact tatttatatc tatacataaa tgtatttggt ataagtaaaa
    45541 taagagtaat ttactataaa aaggaattta atgattgagt gagaatttat tacttaaata
    45601 ttaataatta aataga
//
LOCUS       DAMJYN010000029        45093 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.029, whole genome shotgun sequence.
ACCESSION   DAMJYN010000029 DAMJYN010000000
VERSION     DAMJYN010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 45093)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45093)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45093
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.029"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            405..1055
                     /locus_tag="PC466_001655"
     CDS             405..1055
                     /locus_tag="PC466_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HDF2769043.1"
                     /translation="MDFISSILQGLLSILFNFTGDFGISIVLITLIVKLVLMPLSLKQ
                     RFSVKKQQELAEKMEHIKEKYKNDTKELEKQIQVSSVESMKSMLGCLIVLVQMPVVYA
                     LYHVCLDMTKEFTTIIIPWIANLGTFDNLFILPCIYTLIMLASNLVNYIPYLKINSQV
                     KFNKQMAVVTTITSLILTVRTPVAIGLYFITSAIYSLIEDICFRMYFNRKNRIVTK"
     gene            1269..1940
                     /locus_tag="PC466_001656"
     CDS             1269..1940
                     /locus_tag="PC466_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2769044.1"
                     /translation="MAKILVVEDEKRMQSIIVEYMQKGGYTCITANDGVEALTILKSN
                     NIDLMILDIMMPYLDGFSVCRVSREMTNIPIIILTAKGEEEDKLKGYEYGADDYITKP
                     FSPKVLLAKVNALLRRYTTDIPKNSLSLGKIFIMVASRQVYVEDKLIDLTYKEFELLR
                     LFMENPNQVFSREKLLNCIWGYDFEGNTRTVDTHIKTLRKKLGSEGHHIVTLIRSGYK
                     FEVKE"
     gene            1937..3067
                     /locus_tag="PC466_001657"
     CDS             1937..3067
                     /locus_tag="PC466_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2769045.1"
                     /translation="MNSLRKIIEKLKNVDISNWIKQNFGLYSVRKKVFLLSKLSGALI
                     ILFYLVVEEFSINSKFEFWIWFIILVIFIMSIDFLLGKFISEPITSINKSAKSMSQLD
                     FSNPCTVNTNDEFGELSRSLNTMSTNLQQALSDLESANIQLEKDVNKERMLLEQRKEL
                     VDAISHEMKTPLGIIRAYTEGLMDEVDEEKKKNYMNVIIEETDRMNNMIVSLLDLSAL
                     EAGVSKLNPERFDFIEFVETVAGRLLIDIPDANFYFTYDLPEYEVFVVADKMRMEQVV
                     ENLIINAKKHVVYNGNLDLSITCENGLLLFEIYNDGRIIEQDEISKIWSKFYRSVQSQ
                     RKGGSGLGLAIVSQILTMQGLEYGVNNRDRGVEFYFMIPIDE"
     gene            3472..4317
                     /locus_tag="PC466_001658"
     CDS             3472..4317
                     /locus_tag="PC466_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2769046.1"
                     /translation="MIKVGELKFSYGKDKQILHGLNFEVKEGEIFGFLGPNGSGKSTT
                     QKILNGVLKGYNGHVSLFGKEVKAYTESLYQKIGVLFEFPYLYTNLSAIDNLEYFSSF
                     YPKNQRRDIYELLDLLEFKKEFINKPVSSYSKGMKQRISMARALVSNPKLLFLDEPTS
                     GLDPSGAVLFRKIIEEERKKGTTIFLTTHNMLDADLMCNNVAFIADGKIMVIDKPKNL
                     KMKNSNNKVEVEFVYNGNRDIEIVDIQELESGITFKYDEILSVHSKEPTLEEVFIKYT
                     GRMLV"
     gene            4317..5345
                     /locus_tag="PC466_001659"
     CDS             4317..5345
                     /locus_tag="PC466_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2769047.1"
                     /translation="MYSKFFTLVKKDFWMMIYGKFFVLTLGSLILYSCYINFGYVKFM
                     DEDSYHNNVYLYNPENISMSASPLINQVSSIGELKAKLDEDTSAVCIDMSSSKPKVIL
                     HESIKGVDNYRADYALSLLSSEKDHNSKISDNNAIIQINDKDTSEIKQRKDMTCEILF
                     FEIVAIGFLGIASLLFKEKQMGVMRITGILPVKRSLFILSKIFAFLICDLCFTVLLVV
                     FNIGFFEGVKILPQVLVQASILSIIMSLIGIGCSMLLRDFKQFSLIYLVVAVFITTPI
                     FLSANTSFEIDWIKYHPFYHVYSQLKNAFFMNFSKELVYFVVCSLTIIVLFLLVKYIF
                     NKELVREG"
     gene            5348..6361
                     /locus_tag="PC466_001660"
     CDS             5348..6361
                     /locus_tag="PC466_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2769048.1"
                     /translation="MIGLRYQLKSIKKDKMCIISFFLPVVMAILINFMGTIDISSLGE
                     IRFGIVKDTLPVQTEQWLKKYGMVSVYDTKMHLIREIKDIKTDTIGVVRDGKGIKTML
                     YGNEINAIKNVGKTLPEMFRLKGDLKDVEVTILPKDSILKEFQNVFIAMILITAMFMG
                     CTFNAMNIISEKEDGISFINEVLPQSRSQYIIQKVFLGLLCGCLSSMITVFICLDISI
                     LDMIMMLLLVVFSAFISSLIGLFIGKLSEGLMVGIVYIKIVMILFIGAPLLIYLLGVN
                     TSGIGNLCYIMPSVATFNGIMEIINGNVIIIKDIVILVVHCVVWFMIYIILDKKRKLS
                     FSR"
     gene            complement(6843..8093)
                     /gene="cme"
                     /locus_tag="PC466_001661"
     CDS             complement(6843..8093)
                     /gene="cme"
                     /locus_tag="PC466_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter Cme"
                     /protein_id="HDF2769049.1"
                     /translation="MENKNTNSTWKKKVILFLASQYISLFGSSLVQMAMIWYVTLQTS
                     SGVWVTVLTVCSFIPQMIISFFAGVWADYYNRKVLIIVSDSTIAISTLVLILFMMSSN
                     GTTSELIAISVISVIRSLGSGVQTPAVNAMIPQLVPEEHLMRFNGINSSLQSIVQFIV
                     PIVAAAILGFGNKINQVLLIDVFTAIIAIVLLIFIKIPKHNIPKQTEKVSFFADMVSG
                     IKYCFSDKFIRKVLFTYGAFMLLCVPSGFLIGLLIERTFGKGYIYLSIIEMIGFLVMV
                     LGGLIIGVFGGFKNRNKTFFLAILSYAIFSIILGLVTQAWQFFIFMFFTNFSIPIIQA
                     SAMTMLQEHVAPQMLGRVLSLPIIIYTGFIPLGMMIFGPMADVISINNLIIVAGIILL
                     FFALAIPYSKQFYKQGISKSNESE"
     gene            complement(8179..8925)
                     /locus_tag="PC466_001662"
     CDS             complement(8179..8925)
                     /locus_tag="PC466_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF2769050.1"
                     /translation="MDTYTTSEVADLIGVHPNTVRLYEELNLIPKPKRNTNGYRIFND
                     FHIEQFRFARTALKIEVVQRGLRKDALEIVRTSANRDFDKAISLVNQYLQQLEIEKSN
                     AEEALTIVAQILNGNTPETNKLFLTRKETAEHLNVTIDTLRNWEMNGLLKVKRKQNGY
                     RVYTDEDIKRLKIISALRCANYSLSAILRMLNALSSNPNTNIKTVLDTPKDDDEIISV
                     CDKLITSLKEAEHNAKTMKSHLQIMKKQFS"
     gene            complement(9040..10062)
                     /locus_tag="PC466_001663"
     CDS             complement(9040..10062)
                     /locus_tag="PC466_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HDF2769051.1"
                     /translation="MNKNNCLDLIFEKVDPSSVGMSSEKLSQLEPLIISQYSNINGII
                     IARKGKVVFEKYYNGYNADDTFHVASVTKSIISALIGIAIDKGYIKDVDQKVVDFFPE
                     YTCSPSEICKKAVTIRHLLTMTAPYPFKNMTESLERLCKQKDWIKYTLNQLGQKGEIG
                     TFKYSSAGTHLLSAIITKTTGKSAREFANEYLFKPIGMKVIPDYDMKDFGFEDFFGKN
                     LKGWAKDRQGYSIGGWGLTLSARDMLRFGFLYLNDGIWNNKRIISKSWIEESVKMNSN
                     EYGYLWWICKKDGVLWYSAMGTGGNAICCIPQYDLVIAIPSKIVFKPRDRWEFIEKYI
                     LTSIID"
     gene            complement(10062..12482)
                     /locus_tag="PC466_001664"
     CDS             complement(10062..12482)
                     /locus_tag="PC466_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HDF2769052.1"
                     /translation="MKEIKINGAKIHNLKNIDVSIPKDKLVVATGVSGSGKSSLMFDI
                     VFEEGRKQYLQSLGILAGIDSEDKFDNIQGLAPTIAVQQNIIRQSNPRSTVGTRTNIL
                     NMLALLYSVEGQIMCTMCDTPVSDNLICNNCGYEEERLRPSYFSYNSSDGMCMKCSGH
                     GAYFEINIEKLVLDKHDTLKQVLDRAKITPGYLRVFSKKFNDYLDIQFLQLPEEIRNE
                     VLYGHYENGKKSSSLSKVFHNRYKRGEDLNGVYTMTACSDCNGFKIGEEARRVLLNGK
                     HIGELGKMTILEIDDFLKILINQGNLNTFGTNLVNDILSKTRHLIESRLGHLSLYREM
                     STLSGGEMQRLFLNSHLDSEMDSLIYVLDEPTAGLHESEKIDILKSIKKLKDLGNTVI
                     VVEHDKNTIEMAEHIIDIGPKAGVEGGQLVYQGDLEGLLQSDKSLTGQYLSGKYPMPN
                     RTSNKNITHTDKIPCITIQNANTNNLKNVTVSLPLGAMVGISGKSGSGKSSLISDTLL
                     PLLRSQFNNHTINNQINSSDSEIGDEDDYAVIETIADRLIGTKHISGYSEISQSPIGK
                     NMNSTPASYIGIWDKIRTLFAGQPESLERGFTAGHFSFNSKGACPKCSGSGYEKVWLG
                     NNLSIDHICSECQGKRFNDESLSIKYKNKNIHDILNMSVSESVHFFKDIPNIVSHLNV
                     LEQIGMGYIKLGQPTPTLSGGESQRIKLAKEIGKKRNGNILYVLDEPTTGLSLYDTSK
                     LIQLLDELVENGNSVIVVEHDIDVLNVCDWIVELGPEGGDKGGYIIAEGSPKTLKENP
                     KSITGRYL"
     gene            complement(12568..13488)
                     /locus_tag="PC466_001665"
     CDS             complement(12568..13488)
                     /locus_tag="PC466_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDF2769053.1"
                     /translation="MTNAKSKKEYLNRICKVQDYIEEHLHEPLSLDELSNIAGFSKFH
                     FHRIFKAIEKETLAQYVNRLKLENATAFLIHRTDMTVTDIAHYFGFTDSAVFSRAFKN
                     YYKISPIKYRNNYSKNCKEPYKISQYNRSISKPKCKNTREVKGEIEILELDNMNTIYT
                     RYTGSYGNLTSTFPKLLERLFTYASEQNLLGLENTQILAIYHDNPQFTQEHQLRTSIC
                     MTIPDNIVVKENDNLGNMIIPSGKYLVGHFDISKSEYSDAWDFMYNEWLSNGNYKLRA
                     SFPFEVYLNNPHNHPQNRHFVDIYLPIEPF"
     gene            14098..15024
                     /locus_tag="PC466_001666"
     CDS             14098..15024
                     /locus_tag="PC466_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conserved phage C-terminal domain-containing
                     protein"
                     /protein_id="HDF2769054.1"
                     /translation="MSNSFYQLNSAVLYFNEKRDVNRIRFNHYVMRKENIQRLKGTLP
                     RGQFMMTVRKAASDLDVSISTISRLVNEFIDLGILRLISRGVKGNCCSVYSYVCSENS
                     NAEIVTKNSDIFKNIEKYIDATINNNQKTMKYKHRDELFKNSNTNTYSRINQESIDKD
                     YDLIIHTGYETENETKKKELLKNNLNKKNLNKNTFENLDEDLTEDSTYKNPESIHEII
                     IRKLNSESGKNFKADLSITKALIDKRLKEGYSLEDFYKVIEAKVRRWRYTDMEIYIEP
                     TILFGYEFESYLNEESSLSACNYGDMCYEDMY"
     gene            complement(15212..15832)
                     /locus_tag="PC466_001667"
     CDS             complement(15212..15832)
                     /locus_tag="PC466_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2769055.1"
                     /translation="MVLINILLVDDHMLFAKSLSIALEEYEEIEQFYSTQDIHNLSEM
                     IQDKKIDIVLMDINLRGLSECDGLKVAYNLLETNSTIKIIILTGYDLPVYKHEAKKIG
                     IYGFLNKNISPDSLIDSLLKVYQGVTCFPSENTEVIIEDLTNMEKRILQLICSGKKRK
                     IIADELYISERTLSNHLQHIYDKLDVSSSVEAITKAIKMGYISPVY"
     gene            complement(15804..17387)
                     /locus_tag="PC466_001668"
     CDS             complement(15804..17387)
                     /locus_tag="PC466_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF2769056.1"
                     /translation="MTNFNLKILFLGNYILSLLFMGISTSTETYMNIQSIIPLIISTL
                     LLIDITYITSCNVRENNIISLFCGLLALDSWYLLLSFVTTPIGTIIFKILSTVIVYVS
                     IKFIFLFLFQGSGYNFRKITDILLLITCIGAIVGAFISNRTYACMYGIQFVVSIISFL
                     YIIFYHLKRVVFVIKSEKKPISISVFITIIGFLTYYFFTLRISNHIGNFGIYLTVLVF
                     FMSIHGIALKENDSFPISTVFNIKQRAIFLFISILVISLVVLFANGNFSIILIAINVL
                     FMLIFLCNIILEFNLRDEKNKVVKNSKYTFALEKLQQEEQLKTEFSNFLHDDILQNLL
                     SIKNMMSKSYRPEVQDIIYETLNNLNTCIRNQMQDYHPVILKNLTVKENYQNLIESVS
                     SSFPQKNICVSFKCSDTLFLVEPYDILIYRLIKELLTNVYKHSNGSHAWIALALEKNI
                     IKLNINDNGVKNTSFKTPLDITKITFDIIKHKGIISIKEQVENLGGTISISDNIPHGV
                     CVQITIPMKGDGSYKYFVS"
     gene            complement(17531..19558)
                     /locus_tag="PC466_001669"
     CDS             complement(17531..19558)
                     /locus_tag="PC466_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HDF2769057.1"
                     /translation="MNIFYMAIKNLKKNFSFYSLYLLSVSFVITVFFAFTSFSVNKIM
                     LEKISTDGRVESMCNVISIFLMAFVIFYMAYSNRFFLRRRTKELGIYALLGYRKFTIL
                     SLLTFENVLICSGAFITGLVLGALSHKGIVFGITALLNLSIDNSQIPFFNINAINKTI
                     IFIALVVLVLAISNGKFLYKTSLVKLIRHEKSAEKKLKFRKIPAFMGFIMILSGYCLS
                     LDILRGAKSVWVSIGFYQMGLITMIIIVIGTVLFINSFLPYIMQKSKKNKRTFYTDMK
                     IIAIPNFIYRIRSNSKTLIMLTLLSATTLTVSSVMALSLYYPIASVSRIAPSEIEFRV
                     EKNKQIEDVKQIVSQYTSNTDDIIFTQTNIYKVKSSSKDLPFEYEIGTSKNNLSNSSS
                     SKEVISRESGFECISFSDYYTLLKAQNRTKLLKQLTPLRDNECILMKYQPNNDGYSEN
                     GTIYPLLINGKETPVAVRETSLNNAISFANSVGTLIVNDSIYEQIAQNKLPMTSILSI
                     NGKSIKNNENLYSNISDYLDGSPYLQGYSHRINDLLSINSSTFLLIGFLVVLFFIAVG
                     SILYFNNISAISDSTSDYKILQKMGYDNIQIKKIIKKQVLPFFNIPFLLGILDCIFAT
                     LVYKTALMQNLLGNSFSQYIPVIIAIFLTSVVYLIYYILTIKSCCKIVLKN"
     gene            complement(19571..20320)
                     /locus_tag="PC466_001670"
     CDS             complement(19571..20320)
                     /locus_tag="PC466_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005340256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2769058.1"
                     /translation="MNTILKVNNITKTYNKGQQPSLDKVSFNVSEGEFIGIMGASGSG
                     KTTLLNVLSTIDKPTSGDIFINNINLKSLNDTCAADFRKDNLGFIFQEYFLLDSLTIF
                     ENISVPLTLQKLNPDKIENMVKSLAERFDIASQLNKYPNELSGGQRQRASAVRAIVKH
                     PSILFADEPTGALDSNSATELLHSLQEANEELKTTILMVTHDAYAASFANRILIFKDG
                     HIIKELNKQPNNRHTFYELIIQEIAKLDTKR"
     gene            complement(20617..22269)
                     /locus_tag="PC466_001671"
     CDS             complement(20617..22269)
                     /locus_tag="PC466_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp21"
                     /protein_id="HDF2769059.1"
                     /translation="MNNKNLAILISGMMFFSSSSAIFADNTTKQERLIGKTRYETAVE
                     VSKLGWVQSKTAIIVNGNSIQSALCANPFAKLKNAPILLVNNNSIENSTKAELKRLGV
                     DNVYIVDSGNSISSKVENEIKSLNIKINKIVGNNIYKMSTNVLKEIDKIKKVENVAVV
                     NGLKGLSDAVSIASPAAIHNMPIILVSDENSNDSSINFLNNRSIKKSYIVGGNKILSD
                     NTVKKYPNRERISGSDRNNTNAKIIDKFYKDKKINNVFVAKDGINQENALVDSLSIGV
                     LAAKENSPIMISNGSLVNSQKEFIKNKDIDEITQVGGGYNQKAFEDILKLKNVNIRNK
                     TKKISLIQAKEILKQALPGSDILVCYYDEDDNEYDCKVIKDNILYEIEIDAYSGKIIE
                     IEKDDDLNDNNLGTQNISLDKAKSIALDAVPNGNLIYCKYDAEDNEYEAKVIKNKKTY
                     ELEISAFDGRIVDIDMDNDSDDDFDDNDKNNSNTNDNSSIISAEKAKSIMLDKVPGGK
                     IVKFKYDEDDKEYEGEIIKGKIEYEITINAITGKILEFEIDD"
     gene            22868..23989
                     /locus_tag="PC466_001672"
     CDS             22868..23989
                     /locus_tag="PC466_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HDF2769060.1"
                     /translation="MEAKKLGFGLMRLPIKDENDVTTIDMEHLNKMVDTFLERGFTYF
                     DTAYVYHMGKSEIALRESLVKRHKRESFTIATKLPLMALKKKEEQETIFNEQLEKCGV
                     DYFDYYLLHNIGVSHYEVAKKFDSFKFIEEKKKEGKIKNIGFSFHDSAELLDKVLSEH
                     PEVDFVQLQINYLDWDNESIQSRKCYEVAEKHNKPVIVMEPVKGGTLAKIPEKAEKLL
                     NDYNPDMSISSWAIRFAASKDNVMMVLSGMSNMEQLLDNTGYMQNFKPFVQEEYNIID
                     EAVEIINESILVPCTACQYCVEGCPKNIAIPNYFALYNAEKQALNTGFSTQMVYYNNY
                     TKTYGKASDCIECKQCEESCPQHIKIIDALKNVAETFEK"
     gene            24025..24438
                     /locus_tag="PC466_001673"
     CDS             24025..24438
                     /locus_tag="PC466_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF2769061.1"
                     /translation="MTISEVSKKYELSADTLRYYERIGLIPPVNRNKSGIRSFTEEDC
                     EWVNFIKCMRGAGLSIETLIEYVAMFQQGSSTIKARKELLIEQRNQLAKRIEEMQKTL
                     ERLNFKIDRYEEGIIEKEKVLKSSRNKKMEAVSYE"
     gene            24431..24970
                     /locus_tag="PC466_001674"
     CDS             24431..24970
                     /locus_tag="PC466_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HDF2769062.1"
                     /translation="MSKNVLIVSASPRKGGNSDLLCDQFIQGVLESKNQVEKIFLKDK
                     DINYCTGCGACYEKEASCSQTDDMGEILEKMIGADVIVLATPVYFYTMNAQMKTMIDR
                     TCSRYTEICDKDFYFIVAAADENVADMERTIEGFRGFTSCLNGSKEKGIVYGVGAWNV
                     GDIKGSKAMKQAYEMGKLA"
     gene            complement(25170..25655)
                     /locus_tag="PC466_001675"
     CDS             complement(25170..25655)
                     /locus_tag="PC466_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769063.1"
                     /translation="MSKSELTAETTEEMLEVLSGKDYDIACHLHELGKSLDCKIEPKT
                     GARSYKIVYSTKKPKRSLFTIECNEKKWRVKANLFHLNTYKDAVEECSKTIKDSITKT
                     RTCKKCNSKCIGGSSFDLDGKSYLTCIGSGHYFANMEEMDWKNLEKLITKENNIMQES
                     V"
     gene            26506..26883
                     /locus_tag="PC466_001676"
     CDS             26506..26883
                     /locus_tag="PC466_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003483933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HDF2769064.1"
                     /translation="MSKVVIATEKAPGAIGPYSQAIQVGNIVSTSGQLPIDMKTGELV
                     SDPKEATKASLDNVKAILEQAGTSMDKIFKTTVFVKDLKDFNDINEVYATYFKENPPA
                     RSCVQVAQLPKDAVLEIEAMAVL"
     gene            27291..29087
                     /locus_tag="PC466_001677"
     CDS             27291..29087
                     /locus_tag="PC466_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2769065.1"
                     /translation="MLSKLKEFQQEMIKYTETVASVLDVDIEIVDDRLIRISGTGLYK
                     SKINESVVTEGFIYDNVIQTGQELVVLDICDNQLCIECSHYMKCLNKVIIAVPIKYNN
                     RTIGVIGAISTDKTKKVEISAKIDNYLKFVNHICDLISMKIEEHEASKNSSRKMDMMI
                     EIIENVEKGVIILDINSKISYINNIALKKLDIYKNIIENIVSVESSSNGHELLEIDID
                     NKIYNINAKIIPVYPYINQYDKIIIFDKTYINHKGHGKVNSGWGNSDIESIIGNSEAM
                     LKVKERTKKLAKSNSTVLITGESGTGKELIARAIHAEGSRWNKPFIAINCAAIPENLL
                     ESELFGYIKGAFSGASSGGKVGKFELANEGVIFLDEIGDLSMPLQAKLLRVLQERKFA
                     RIGSNKLIDLDIRVIAATNKNLLKLVNEGKFRDDLYYRLNVIPINLPPLRERKDDIEA
                     IMMKFASKYSLELGIQLNKIEENVMNMLINYNWPGNIRELENAVEYMMNLVGDDGIIY
                     KDMLPLDILNYYNINGNVCKNKDINIIFEDDIVGGIVENQERILSIKELELTYINKLL
                     NKYGRDTKTKKKIAKDLGIGLATLYRKLEEEQ"
     gene            29164..29703
                     /locus_tag="PC466_001678"
     CDS             29164..29703
                     /locus_tag="PC466_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2'-5' RNA ligase family protein"
                     /protein_id="HDF2769066.1"
                     /translation="MQYAIELYYDKKTEKQLFDLSKKIADEKISTKYLEWKTRPHLTL
                     ACFNDVDEACCIDKLKGFAQNHKVIPAYIGSVGMFNDTKTVFVSPIMNSSMYQFQREL
                     YEVLQDFDSNGWEWYHPNRWVPHCTIALTGDDESEAFFRASDVLLREFKKISGEFVSI
                     GLVKITFPVEEIFTVNMNR"
     gene            30326..31540
                     /gene="dpaL"
                     /locus_tag="PC466_001679"
     CDS             30326..31540
                     /gene="dpaL"
                     /locus_tag="PC466_001679"
                     /EC_number="4.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopropionate ammonia-lyase"
                     /protein_id="HDF2769067.1"
                     /translation="MREIKWKLNNLPKSEEKEKGIEFLRDEEIAKAKAFHESFPQYEK
                     TPLVKLDNLAKSLGVSGIYVKDESYRFGLNAFKVLGGSYSMGRYLAQRLDTDISELGY
                     DKLTSKEIKEKLGEITFFTATDGNHGRGVAWTANKLGQKSVVLMPKGSSEFRLNKIKG
                     EGADASITDLNYDDAVRLANDYAEADDHGVMVQDTAWDGYEEIPAWIMQGYGTMAKEA
                     IEQLKEYGVDRPTHVFVQAGVGSLAGAVQGYVASIYDECPITVVVEADEADCYYKSAE
                     AGDGKPRFVGGDMPTIMAGLACGEPNTIGFEVLKNYSSAFVSAPDWVSAKGMRILGNP
                     LRGDEKVISGESGAVTTGALVSILESEDLKDLREALKLDENSKVLLISTEGDTDPDKY
                     RDIVWNGECQSK"
     gene            31873..33060
                     /locus_tag="PC466_001680"
     CDS             31873..33060
                     /locus_tag="PC466_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgeY family selenium metabolism-linked
                     hydrolase"
                     /protein_id="HDF2769068.1"
                     /translation="MLNETRKKQLTEVCQDLIRNASYSGQEENVVKAIEENFALLGFD
                     SWSRDRYGNIVGCIKGNKPGKKILFDGHIDTVPVPDASKWSVPPFEARIVDGKIYGRG
                     TSDMKGQVSAMMAAVSYFAEDTNKDFEGELYVAGVVHEEIFEGVSAREISKAVQPDYV
                     VIGESSELNLKIGQRGRGEIVVETFGKPAHSANPEKGINAVYKMANVIQKIQQLVPPT
                     HPVLGDGILVLTDIKSSPYPGASVVPDYCKATFDRRLLVGETREGVLAPIQALLDEMM
                     KEDPELNAKVSYAVEKADCYTGNTIESERFFPGWLYDEEDEFVQAAYNGLKEAGIDSE
                     ITQYSFCTNGSHYAGEAGIRTIGFGPSKENLAHTIDEYIELDQLFKGAEGYYGILKSV
                     YKK"
     gene            33076..34659
                     /locus_tag="PC466_001681"
     CDS             33076..34659
                     /locus_tag="PC466_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacylase"
                     /protein_id="HDF2769069.1"
                     /translation="MRTLIKHGLIVDGNKTPAYEGDILIENEKILKISQDLNEEADKV
                     IDAKGRVICPGFIDTHSHSDLVILVNPYNEVKIRQGITTEVLGQDGISMAPLPQEHIS
                     SWRKNLAGLDGESDEIDWKYETTENYLKMMDYNGVGLNETYLVPHGNVRMEAMGLEDR
                     PATKEEIQKMCEITERELKAGAIGLSTGLIYIPCAYSLTEEIIEMCKVVAKYDGVFVV
                     HQRSEADTILTSMEEIIEIGKQSGVKVHFSHFKVCGKANWKYIPQVIELLEKAEKEGI
                     RVSFDQYPYAAGSTMLGVVLPPWAHSGGTDKLIERLSDENERAKMKKDIANGIEGWDN
                     FIEFAGIDQIFVTSVKTEKNKDTIGKSLLEIGKMRGKDPLDATFDLLKEEENAVGMVD
                     FYGLEEHIIGFMKRDEQNVCTDGLLAGKPHPRAYGSFPKILGRYVRELNVLTIEEAVY
                     KMTKKAATSFSIKDRGELKEGYFADIVIFDKDTVSGCDDFINSMQYPTGIDYVIINGN
                     CVVEEGKYNKIKAGKVLKN"
     gene            34687..36015
                     /gene="ssnA"
                     /locus_tag="PC466_001682"
     CDS             34687..36015
                     /gene="ssnA"
                     /locus_tag="PC466_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative aminohydrolase SsnA"
                     /protein_id="HDF2769070.1"
                     /translation="MILVGNGRLISQDSLNPYMEDGCVVINDNLIEDIGTTEEMKAKY
                     PVHEFIDAGKKIIMPGLINSHMHIYSSFARGMAVPGKPSENFLEILNNLWWRLDKQLT
                     LEDTKYSAYATYIECIKNGVTTVYDHHASPNAIEGSLFTISDVAKDLGIRTCLCYEVS
                     DRDGGNTIQQGINENVNFIKYAQKDDTDMIKGMFGLHAAFTLSDDTLNKCASEMAGLD
                     TGYHVHVAEGLADLQYNVDKYGKRVLERFNDFGVLKEKTIAVHCIYISAEEISLLNKT
                     NTFVVHNPESNMGNAVGCSPAIELLKRGVTVGLGTDGYTSDMFESLKVANIIHKHHLK
                     DPRVGFEESQTMLFDNNRKIAKAYYKNDLGVLKKGAYADVIVVDYIPHTPLTENTIGG
                     HTIFGMSGRSVDTTIINGKVLMKDRKLINIDEESILAKSRELSQNLWNRI"
     gene            36214..37566
                     /locus_tag="PC466_001683"
     CDS             36214..37566
                     /locus_tag="PC466_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HDF2769071.1"
                     /translation="MSQDKSPKIAPVDERLPVSKSWVFSLQHVLAMCAGAVAVPMMIG
                     SAARLDHASIVFLINACLFMAGIGTLIQSVGIGNIVGAKIPVIEGTSFAAVAGMTAIA
                     SSYSDSQVAIQTVFGSVIVAGLFCILLAPVFEKLIRFFPSVVTGTVVMVIGISLFPVG
                     IKWITDNKLEAVEPNSLALALAVLAITLLSFKFLKGIWNSTAILVGIVLGTLLSMAVG
                     MADFSAVNGVGWLNLNVPLKFGMPRFEPSAILSLCLIMLVLMTESVGNMIAIHEMVDK
                     EVTGKNIKRGLFGDGISTALSGIFNSFPITPFGQNTGIVGLTGIKSRFIAVYAGVILL
                     VLGFLPKFAAIIGAIPKPVLGGVGFAMFGMVMVGGVKTLSKVKFDGTKNGVIVAVSVG
                     LSMIPLTNPDFYHNFPTWVQTIFHSGITTGSLSAVLLNIFFNELGSKKEKNNKVEEAK
                     "
     gene            37758..38867
                     /locus_tag="PC466_001684"
     CDS             37758..38867
                     /locus_tag="PC466_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDF2769072.1"
                     /translation="MANLKVNLYGMEFLNPIMTAAGPGAKDGALCQEAAKGGAGAICT
                     KTISVLPADVPRPCMAKTNSGFLNTELWSELPKEQWIEEEYKKVKETGLPVIVSMGYS
                     AEQIAEVAPLVKPYADAVELSTHYVGTDVAPIVNALKAAKAVLDVPVFMKMSPHTDIQ
                     TIAKAVEEAGADGLVMINSFGPCMAIDVNTGYPIMGSKAGYGWLSGAPIRPLAIRCIY
                     EASQVVNIPIIGVGGITCGKDVAEMMMAGASAVQVCTEAILKGPSIYGKIAKELNEFL
                     DENGYADVNEIKGLTHKKMAARGFRTHSVAPVVDDNKCIKCKQCVTSCVYEALEVTDK
                     LNIDADKCFGCGLCVTRCPKGALSICYNQVEAMNE"
     gene            39150..40541
                     /gene="hydA"
                     /locus_tag="PC466_001685"
     CDS             39150..40541
                     /gene="hydA"
                     /locus_tag="PC466_001685"
                     /EC_number="3.5.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropyrimidinase"
                     /protein_id="HDF2769073.1"
                     /translation="MGIVLKGGKVVTSEKTYCADVRIEDEKIVDIGLDISKENDEIVD
                     VSDSYVIPGGIDTHTHFDLDTGVTKTADNFETGTKAAIVGGTTTILDFATQAKGCSLK
                     DGLEEWHEKAKDKSYSDYGFHMAITDWNDSVCNEMEDMVKEGVSSFKLYMAYKGSLQV
                     DDGVIFEALRKAEEIGGIIGFHCENGDIICELVDKAKSENNLSPKYHQLTRPAIMEAE
                     ATSRLMKIAEVANSKVYVVHLSCKESLEEVLKAKQRGVDVIVETCPQYLLLNDELYDL
                     DGFESAKYVMSPPLRNKENNEILWNAILDNQIDTIGTDHCSFNYKGQKELGINDFSKI
                     PNGSPGVEHRMSLLYTYGVCKNKISINKMVEVTSTNAAKLFGMYPNKGTIEIGSDADI
                     LVLNPNKKSKIEAKKQLQNVDYTPYEGYEVDCQIEHVYLRGKEVVRDGELICNTPSGR
                     YINRRLTKGAREW"
     gene            40535..43096
                     /gene="xdh"
                     /locus_tag="PC466_001686"
     CDS             40535..43096
                     /gene="xdh"
                     /locus_tag="PC466_001686"
                     /EC_number="1.17.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenium-dependent xanthine dehydrogenase"
                     /protein_id="HDF2769074.1"
                     /translation="MVEFILNGEKVVAKEGKKLLDFLREDMNITSVKNGCSEGACGTC
                     MVIIDGKATKACVFKTDKLAGKNITTIEGLSERERDVFAYSFASQGAVQCGFCIPGMV
                     ISSKALIDVNNNPTEDDIKKALKGNICRCTGYVKIIKAVDLAAKIFRENIDVPKVNCK
                     GLVGENLPRVDAVGKALGYSEYVDDMRIEGMIYGSAVRAKYPRALVKKIDIEEAKAYP
                     GVVAVLTAKDIPGTIKVGHLKKDWDTLIPEGEITRYLGDGIVLVAAETREALEEAKKL
                     VKIDYEELTPLSTTADALREDAPKIHETGNILVKEHLVRGNAKEKIENSKYVVTKRYT
                     TPATEHAFLEPECAVAGPYEDDGVIIYSTDQGVFATQHECADMLGLPYEKVRVINKMV
                     GGGFGGKEDMSVQHHAALLAYHTKRFVKVQLTRKESIIVHPKRHATEMEFTTACDENG
                     YLTGMKATIISDTGAYASLGGPVLQRLCTHAAGPYNYQDIDITGTAVYTNNPPGGAFR
                     GFGVTQSCFATECNLNLLAEMVGISPWEIRYKNAIRPGQVLPNGQFADEGTAMAETLE
                     AVKEEYEKHPRAGIACAMKNSGVGVGIPDVGRCRLVIKDGKVHIRTSASCIGQGLGTV
                     MTQVVCETASLLPENIVHEVPDTHLTPDSGNTTASRQTVFTGEATKVASNKLKEALDS
                     GKTLLDLEGEEFYGEYESITDKMGCDKENPVSHVAYGYATQVVILDENGKLEKVVAAH
                     DVGRAINPISLEGQIEGGVVMGLGYALTEDYPVVNSVPTAKFGTLGLFKSTDIPEIQA
                     LIVEKNKDLLAYGAKGVGEICTVPTAPAVQNAYYVFDKEFRTELPLQNTPYSKKK"
     gene            43248..44594
                     /gene="rpoN"
                     /locus_tag="PC466_001687"
     CDS             43248..44594
                     /gene="rpoN"
                     /locus_tag="PC466_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HDF2769075.1"
                     /translation="MNFNNSLELTQSQKLIMTTQLKQSLSILNMSKLELEEEIKREAE
                     NNPLVEVEKSGEINWEEYIKDMDRSRRLDRTEISYNPDNEVNLENLVKYSSNLYEDLK
                     FQISLYKLTDKELEVCEYIIDSLDEDGYLRTEEKVIVDTLKIDEELFEKCLISVQQLE
                     PSGVGARSLSECLMIQMASLGIYNEILEEIVTKDLNLIANNKYKEISKKYNMSLQKCV
                     ELINIIKTLDPKPGRTCSVEKSVYIQPDVTVEKIDDEFIVYLNEKDSYQIRINSYYKD
                     ILKNSQSDESAKEFIKERLNSATGLMKNIESRKTTVLKIAEEIVKAQDEFLRKGTKYI
                     KPLKMKDIAEKLEFHESTISRGVNGKYMLTPFGVYEFRYFFSSAIETENNEMASSTSI
                     KKIIKETIKDENKKKPLSDDHISKLLKEKGINVARRTVAKYREELGIPSSSKRKEY"
BASE COUNT        17011 a         5513 c         7639 g        14930 t
ORIGIN      
        1 tacattagga gttttctata ctataattat ttatatttaa aactaaatat aaatgttgga
       61 attatttagg atttgaaatt gtctaaagat aaatataagt gatgaagagg tgatgtgatg
      121 agattagata tggatagtat gttatatgta ctaatttata tgacattatt ggtatctatc
      181 attggaagta tattttattt ttgtaaagac ctcttaaatc ataaaattaa gtatgtttta
      241 ataagagaca tatttgtaaa tagaattaca tattctgaag aacggttgcc taaacagtat
      301 atagtttttc agaaatatga tatttggagg tattgtagtt tgttttaatt tgaaatgaat
      361 ctattataaa ttctaaagtt taaaaataaa aaggagagaa taaaatggat ttcatttcaa
      421 gtatattgca aggattatta agtatattat ttaattttac aggtgatttt ggaatttcta
      481 ttgtacttat aactttaata gttaaattag tacttatgcc actatcatta aaacaaagat
      541 tttctgtaaa aaaacagcaa gaattagctg aaaaaatgga acatataaaa gaaaagtata
      601 agaatgatac taaagaattg gaaaagcaaa tacaagtaag ttctgtagaa agtatgaaga
      661 gtatgctggg atgtcttata gttttggttc aaatgccagt agtatatgct ttatatcatg
      721 tatgtttaga tatgacaaag gaatttacaa caattataat tccatggatt gctaatttag
      781 gtacatttga taatttgttt atattacctt gtatatatac attaattatg ttagcttcaa
      841 atttagtgaa ttatatacca tatttaaaaa taaattctca agtaaagttt aacaaacaaa
      901 tggctgtggt gactaccata acaagtctta tactaactgt tagaactcca gtagccatag
      961 gtctgtactt tataacaagt gcaatttatt cattaattga agatatttgt tttagaatgt
     1021 attttaatcg aaaaaataga atagtgacaa aataatataa ttattattag aaatatttta
     1081 gcctgctaac atagaaaaag ttagtaggct atttttatct atgatatcaa ttccattaag
     1141 aatagtctaa aaaatactat caaaatgcta taaaaaatac tataaaaata ctataaaaaa
     1201 atagttgaaa aataaataaa ttaatataaa ctaaaataaa gcctacaaaa aagaggtgat
     1261 aaatagaaat ggctaaaata ctagttgtag aagatgaaaa aaggatgcaa agtattattg
     1321 tagaatatat gcaaaaggga ggatatactt gtataactgc taatgatgga gtcgaggcac
     1381 ttacaatatt aaagagcaac aatatagatt taatgatatt ggatattatg atgccgtatt
     1441 tagatggatt ttcagtgtgt agagtttcac gtgaaatgac taatatacct attatcatat
     1501 tgacagctaa aggtgaagag gaggacaaat taaagggtta tgaatatggc gcagatgatt
     1561 atataacaaa accatttagc ccaaaagtac ttttagcaaa agttaatgcc ttgttacgta
     1621 gatacactac tgatattccc aaaaattcat tgagtttagg aaagattttt attatggtag
     1681 catcaaggca agtgtatgta gaagataaat tgattgattt aacatataaa gaatttgaat
     1741 tattgcgttt atttatggaa aaccctaatc aagttttttc cagagagaag cttttaaatt
     1801 gtatatgggg atatgatttt gaaggaaaca cacgaactgt agatacacat ataaaaacct
     1861 tacgcaaaaa gcttggtagt gaaggacacc atatagttac attaattcgt tcaggatata
     1921 agtttgaggt taaggaatga atagtttaag aaagattata gaaaaactga aaaatgtaga
     1981 tatttcaaat tggattaaac aaaattttgg actatattca gttagaaaaa aagtgttttt
     2041 actttctaaa ttatcaggag cgttaattat attattttat ctggttgttg aagaattttc
     2101 gataaactct aaatttgaat tttggatttg gtttataata ctggttatat ttattatgag
     2161 tattgatttt ttattgggaa aatttatttc agaaccaatc acatctataa ataaatctgc
     2221 aaaaagtatg tcccaacttg atttttctaa tccatgtact gtaaatacta atgatgaatt
     2281 tggagaactt tctaggagcc tgaatacaat gtctacaaat ctacaacagg cattatcaga
     2341 cctagaaagt gcaaatattc aacttgaaaa ggatgtaaat aaggaaagaa tgctattgga
     2401 acaaagaaag gagttggtag atgcaatttc acatgaaatg aagactccac ttggcattat
     2461 acgtgcgtat acagaggggc ttatggatga agttgatgaa gaaaaaaaga aaaattatat
     2521 gaatgttata atagaagaaa ctgatagaat gaacaatatg attgtatcat tattagactt
     2581 atctgcattg gaagcaggag tttctaaact taacccagag cgttttgatt ttatagagtt
     2641 tgttgaaact gtggcaggtc gtcttttaat tgatatacca gatgccaatt tttattttac
     2701 atatgatttg ccagagtatg aagtttttgt agtggcagat aaaatgagaa tggaacaagt
     2761 agtagagaat ctaattatta atgcaaagaa gcatgttgta tataatggta atttagattt
     2821 atcgattaca tgtgaaaatg gcttgctttt atttgaaatt tataatgatg gtaggattat
     2881 agagcaagat gagatttcaa agatttggtc taagttttat cgtagtgttc aatctcagcg
     2941 taaaggaggt tcaggtctag ggcttgcaat tgtttcacaa atacttacaa tgcaagggtt
     3001 agaatatgga gtgaataatc gtgatagagg agtagagttt tattttatga ttccaattga
     3061 tgaataattt agtattaatt tataaattat aagtatctga tgtaaaatat ttttctttgt
     3121 atacgtaagt atttaaagag aataaaataa aaaacttaat gaaaaagtct aataaaaagt
     3181 ttaatgaaaa gtcttgtttt cctgatgaaa acaagatttt ttattaagct ttttattatt
     3241 tcacttcgat ttcacaagag agacactctg atttcaccaa atagaaataa aataggttaa
     3301 ataaattaaa aaatagaagc gtaattaaat aaggttacaa gggggagtac ttatgaaatg
     3361 gtatacatgg ttgactatta tattgataat attgctttct attccgctta aaattaaatt
     3421 tataaaatgg tgggatagac gacaaaaaaa tgataaagga ggttatgata gatgataaaa
     3481 gtaggagagt taaaattttc ttatggaaaa gataaacaga tattgcatgg acttaatttt
     3541 gaagtaaaag aaggagaaat ctttggattc cttggaccta atggttcagg aaaatccaca
     3601 acacagaaaa tcttaaatgg cgttttaaaa ggttacaatg ggcacgtatc cctttttggg
     3661 aaggaagtta aagcatatac agagtctcta tatcaaaaga ttggtgtttt atttgaattt
     3721 ccttatttat ataccaattt aagtgcaatt gataatttag aatatttttc gtctttttat
     3781 cctaaaaatc aaaggagaga catatatgaa ctcttagatt tgttagagtt taagaaagag
     3841 tttataaata agcctgtatc atcctactca aaaggtatga agcaacgtat tagcatggca
     3901 agagcattgg taagtaatcc aaagttgtta tttttagatg agcctactag tggacttgac
     3961 ccatctggag ctgtactatt tcgtaagatt attgaagaag aacgaaaaaa aggaacaact
     4021 atctttttga ctactcataa tatgctagat gcagatttaa tgtgtaacaa tgtggctttt
     4081 attgcagatg gcaagattat ggtaatagat aaacccaaaa atttaaaaat gaaaaatagc
     4141 aataataaag ttgaagtgga atttgtatat aatggaaatc gagatattga aattgtagat
     4201 atacaagagt tagaatctgg aataactttt aaatatgatg aaatcttaag tgtacattca
     4261 aaagaaccta cactagaaga agtttttatt aaatacacag gaaggatgtt agtgtaatgt
     4321 attctaaatt ttttacctta gtaaaaaaag atttttggat gatgatttat ggtaaatttt
     4381 ttgtgctgac acttggctct ctcatacttt attcgtgtta tattaatttt ggttatgtaa
     4441 agtttatgga tgaagatagt tatcacaata atgtatatct atataatcca gagaatataa
     4501 gcatgagtgc atctccatta attaatcaag tttcttctat aggtgaatta aaagcaaaac
     4561 ttgatgaaga tacaagtgca gtttgtattg atatgagttc cagtaagccg aaagtaattt
     4621 tacatgaaag tattaaagga gttgacaatt atagagctga ctatgcattg tcattattat
     4681 catcagaaaa agaccataat agcaaaatat cagacaacaa tgcaataatt caaattaatg
     4741 ataaggatac atctgagata aaacaaagaa aagacatgac ttgtgagatt ttattctttg
     4801 aaattgtagc tattggattt ttagggattg cctctttatt atttaaagaa aagcagatgg
     4861 gagtaatgcg tattactggt attttacctg taaaaagaag tctttttata ttatcaaaga
     4921 tatttgcttt tttgatatgt gacctatgtt ttacagttct tttagtagta tttaatattg
     4981 gattttttga aggagtaaaa atacttccac aagtattagt tcaagctagt attttatcaa
     5041 ttattatgtc tttgattgga ataggatgct caatgttatt gagagatttt aagcaatttt
     5101 ctcttatata tcttgtggtt gctgtattca taactacacc tatatttcta tctgcaaata
     5161 catcttttga aatagattgg attaaatatc atcccttcta tcatgtttat agtcagctta
     5221 aaaatgcgtt tttcatgaat ttttcaaaag aattagttta ttttgtagtg tgttctttga
     5281 caataatagt tctattttta cttgtaaaat atatttttaa taaagagttg gttagggagg
     5341 gataatcttg ataggattac gttaccagtt aaagagtata aaaaaagata aaatgtgtat
     5401 aatttccttc tttttaccag ttgttatggc gattttaata aattttatgg gaacaattga
     5461 tatatcttca ttaggagaga tacgttttgg tatagtgaag gatacacttc ctgtacaaac
     5521 agagcagtgg ttgaagaagt atggtatggt aagtgtatat gacacaaaaa tgcatttaat
     5581 acgtgaaatt aaggatatta aaacggacac aattggagtt gttagagatg gtaaaggaat
     5641 aaaaactatg ctttatggaa atgagattaa tgctataaaa aatgttggaa agacattgcc
     5701 agagatgttt agactaaagg gtgatttaaa agatgttgag gttacaatat tgcctaaaga
     5761 tagtatttta aaagagtttc agaatgtttt tattgctatg attttaatta ctgctatgtt
     5821 tatgggatgt acctttaatg caatgaatat tatatctgaa aaagaagatg gaatatcatt
     5881 tataaatgaa gttttgccac agagtagaag tcagtatatt atacaaaaag tatttttggg
     5941 tcttttatgt gggtgtttat cttcaatgat aactgtattt atatgtttgg atatttcaat
     6001 attagatatg ataatgatgt tgttactcgt tgtattttca gcatttattt catcacttat
     6061 aggtttattt attggaaagt tgtcagaagg tcttatggta ggaattgttt atattaaaat
     6121 agtaatgatt ttatttatag gtgctccttt gttaatatat cttctagggg ttaataccag
     6181 cggtataggg aatttatgct atataatgcc atcagttgct acatttaatg gtattatgga
     6241 gattattaat ggtaatgtta ttattataaa agatattgta attttggttg tacattgtgt
     6301 agtatggttt atgatatata ttattttaga taaaaaaaga aagttatctt ttagtagata
     6361 actcagtata attataattg ggacaattta ataggtgatt taatatactt tgtatagtgt
     6421 aatttatgta gtgcaatttg tatactttaa tttatgtagt gtaatagtta gttttatttt
     6481 ataattattc aatataattt agtaagaaat tcagtacaat tagagctact tagtggaaaa
     6541 cttaataggt acttaaacta tataaatact ttattttcct ccatttgtac tataaattta
     6601 atttatgata taaatggagg tattattata tgaggtatta ttatataaag ttaataaaga
     6661 tagtatcaaa atattatttg ctataaagag agggactcaa aataaagata aacctatttt
     6721 tcaatgttga aatgataaaa tatatttgat ttcatataaa aaattttctt cataaattaa
     6781 aaagtccatt ttaagccccc tcatttttaa ccagataaat cgagttaaac tatttaaata
     6841 tattactcgg attcatttga cttagatatt ccttgcttgt aaaattgttt tgaatagggg
     6901 atagccaaag caaaaaataa aagtataatc cctgctacga ttattaaatt attaatagaa
     6961 attacatctg ccattggtcc gaaaatcatc ataccaagag gaataaaacc agtatatata
     7021 ataataggta agctaagaac tcgacctagc atttgtggtg ctacatgctc ttgcaacata
     7081 gtcatagctg atgcttgaat aattggaatt gaaaaattcg taaaaaacat aaatataaaa
     7141 aattgccaag cttgtgttac aagacctaga ataattgaaa aaatagcata ggataatatt
     7201 gctagaaaaa aggtcttatt tctattttta aaaccaccaa aaactcctat aatcaatcca
     7261 cctaaaacca taactaaaaa tccaatcatt tcaataatag acaggtatat ataacccttg
     7321 ccaaatgttc gttcaataag aagtcctata agaaatcctg atggaacaca aagaagcatg
     7381 aatgctccat aagtgaaaag cacttttcta atgaacttat ctgaaaaaca gtactttatc
     7441 cctgatacca tatctgcaaa aaatgagact ttttcagttt gttttggtat attatgttta
     7501 ggaattttga tgaatatcaa taatacaata gcaataattg cagtaaatac atcaattaaa
     7561 agaacttgat ttattttatt accaaatcca agtattgcag cagctacaat aggcactata
     7621 aattgtacta tagactgtag actactattt ataccattaa aacgcattaa atgttcttct
     7681 ggtacaagtt gaggaatcat tgcgtttaca gcaggtgttt gtacaccact tcctagtgaa
     7741 cgtataacag atattactga tatggctatt aattcacttg ttgtgccatt tgatgacatc
     7801 ataaatagaa ttagaactaa tgtagatata gcaattgttg aatctgatac aattatgagt
     7861 acctttcgat tgtagtagtc tgcccataca ccagcaaaaa aagaaattat catttgaggt
     7921 ataaaggagc atacagttaa aactgttacc catacacctg atgatgtctg aagtgtgaca
     7981 taccatatca ttgccatttg tacaagtgat gagccaaata aggaaatata ttgacttgct
     8041 aaaaaaagaa tgactttttt cttccatgta gaattagtat ttttgttttc catcctattc
     8101 ctcctttgat ttgtgtgttg aatttttctt gctcttaagg ataacacaca aatcaaagtc
     8161 tggagttaga gtggagggct aggaaaattg ttttttcata atttgaagat gagatttcat
     8221 ggtttttgca ttatgttcag cttctttcaa tgaagttatc agtttgtcac acactgagat
     8281 aatttcgtca tcatcttttg gagtgtcaag gacagtttta atattagtat taggattaga
     8341 agataaagca tttaacattc gtaaaatagc tgaaagagaa tagtttgcac aacgaagtgc
     8401 gcttataatt ttaagtcgtt ttatatcttc atcagtatat acacgataac cattttgttt
     8461 tctttttact tttaacaaac cattcatttc ccaatttctt aaagtatcta ttgtaacatt
     8521 taagtgttct gcagtttctt ttctagttaa aaagagttta tttgtttctg gagtatttcc
     8581 atttaaaatc tgtgcaacaa tagtaagtgc ttcctcggca ttagattttt ctatttctaa
     8641 ttgttgcaag tattgattta caagactaat agccttatca aagtccctat tcgctgatgt
     8701 tcttacaatc tcaagggcat cttttcttaa tcccctttgt accacttcaa ttttcaaggc
     8761 tgtacgagca aatctaaatt gttctatatg aaaatcatta aagatacgat aaccattggt
     8821 attacgctta ggtttaggta ttaagtttag ttcttcatat aaacgtactg tattaggatg
     8881 tacaccaatt aaatctgcta cctctgatgt cgtgtaagtg tccattagta ttcaactcct
     8941 tttagatata tagtattagt cataataaca ccaaacaaaa gtctggtgtt atagtggagg
     9001 gtttggttat ctaagagtaa ttagtttatc taagagtgat taatctatta tagaagtaag
     9061 tatatatttt tcaataaact cccatctatc acgaggttta aacactattt tagatggtat
     9121 ggctattact aagtcatatt gtggaataca acaaatagca tttcctccag ttcccattgc
     9181 tgaataccac aaaacaccat cttttttaca tatccaccac agataaccgt attcattact
     9241 attcatttta accgattctt caatccacga tttagatata atacgtttat tattccaaat
     9301 accatcattt aaatacagaa aaccaaatcg caacatatct ctagcactca atgtaagtcc
     9361 ccagccacct atagaataac cctgtctatc ttttgcccaa cccttaagat tttttccaaa
     9421 gaaatcttca aaaccaaaat ctttcatatc ataatctggt ataactttca taccaatagg
     9481 tttaaataag tactcattag caaattcacg agcagatttt ccagtagttt ttgttataat
     9541 agctgaaagt aggtgcgttc cagctgaaga atatttgaaa gtaccaattt cgcctttttg
     9601 accaagttga ttcaaggtat attttatcca atctttttgt ttgcaaagtc tttctaaaga
     9661 ctcagtcata tttttaaaag ggtatggtgc agtcattgta agtaggtgac gtatagttac
     9721 tgctttttta catatttcag aaggactaca agtatattca gggaaaaaat caacaacctt
     9781 ttggtcaaca tcttttatat atcctttatc tattgcaata cctattaagg ctgatataat
     9841 actttttgta actgatgcaa catgaaaagt atcatcagca ttatatccat tatagtactt
     9901 ttcaaagaca acttttcctt ttcttgcaat aattattcca tttatattac tatattgtga
     9961 gattattaaa ggttccagtt gtgagagctt ttctgaactc atgccaacac ttgaagggtc
    10021 tactttttca aatattaaat ctaagcaatt gtttttattc attaaagata cctccctgtt
    10081 atagattttg gattttcttt tagagttttt ggagaacctt ctgcaattat ataacctcct
    10141 ttgtcaccac cttctggacc aagctcaaca atccagtcac aaacatttaa tacatctata
    10201 tcatgttcaa caacaattac agaatttcca ttttccacca attcatctaa taattgaatc
    10261 aacttagaag tatcatatag acttagacca gtagttggct catccaatac ataaaggata
    10321 ttaccatttc gttttttacc aatttctttt gcaagtttga ttctttggga ttcaccacca
    10381 cttaaagtcg gtgtaggttg gcctaatttt atatacccca tacctatttg ttctaataca
    10441 tttaagtgtg aaacaatatt tggaatatcc ttgaagaaat gtacagattc agaaacactc
    10501 atatttaaaa tatcatgtat atttttattt ttatatttaa tagataaaga ttcatcatta
    10561 aatctttttc cctgacattc actgcatata tggtctatac ttagattatt tcctaaccag
    10621 accttttcat atccactacc actacattta ggacaagcac ctttggagtt aaatgagaaa
    10681 tgaccagctg taaatcctcg ttctaacgat tctggctgac ctgcaaatag tgtacgtatc
    10741 ttatcccata taccaatata agaagcagga gttgagttca tatttttgcc aataggagat
    10801 tgagatatct ctgaatatcc agaaatatgt ttagtaccaa tcagtctatc tgcaatagtt
    10861 tcaataactg cataatcgtc ttcatcacct atttcgctat ctgaagaatt tatttgatta
    10921 ttgatagtat ggttattaaa ttggcttcta agaagaggaa gtagggtgtc tgatataagt
    10981 gaactcttgc cactacctga ttttccagat attccaacca tagcacccaa aggtaatgat
    11041 acagttacat ttttaagatt atttgtattt gcattttgaa tagttataca aggtatttta
    11101 tcagtatgtg taatattttt attgcttgtt ctattaggca ttggatattt tccagataga
    11161 tactgcccag taagtgattt gtcggattga agtagacctt ctaaatctcc ttgatatact
    11221 aattgaccac cttcaacacc agcttttgga ccaatatcaa taatatgttc tgccatttca
    11281 attgtgtttt tatcgtgctc aactactatg accgtattgc ctaaatcttt aagtttcttt
    11341 attgatttta agatgtctat tttttctgat tcatgcaatc cagctgttgg ttcatcaagc
    11401 acataaatta atgagtccat ctctgaatcg agatgtgaat ttaaaaatag tctttgcatt
    11461 tccccaccac tcaaagttga catttctcgg tataaggata gatgacctaa tcgtgattct
    11521 attaaatgtc gagttttgga taaaatatca tttacaagat ttgtaccaaa tgtgtttaaa
    11581 ttaccttggt ttattaagat tttaaggaaa tcatcaattt ctaaaatcgt catttttcca
    11641 agttctccaa tatgttttcc gtttaaaagt actctacgtg cttcttcacc aattttaaaa
    11701 ccattgcaat ctgaacaggc agtcatagta taaactccat ttaaatcctc accccttttg
    11761 taacgattgt gaaatacctt tgataaagag gaactttttt taccattttc ataatgacca
    11821 tagagtactt catttcttat ttcttcaggt agttgtaaga attgtatgtc taaataatcg
    11881 ttgaattttt tagaaaatac tctcaaatat cctggtgtaa tctttgctct atctaagact
    11941 tgttttaggg tatcatgctt atcaaggact aatttttcaa tattaatctc aaaatatgca
    12001 ccatgtccag agcacttcat acacattcca tctgaagagt tgtatgagaa ataacttggt
    12061 cttaatcgtt cttcctcata cccacaatta ttgcaaatta gattatcgct tacaggagta
    12121 tcacacatag tacacattat ttgaccttct actgaataca atagtgcaag catgttgaga
    12181 atattggttc ttgtgcctac tgttgaacga ggattgctct ggcgaataat attttgttga
    12241 acagctatag tgggagctaa accttgaata ttatcaaact tatcctcact atcaatacct
    12301 gcaagtatac ctaaagattg cagatattgt ttacgacctt cctcaaatac aatgtcaaac
    12361 ataaggctag acttacctga gccactgaca cctgttgcaa caacaagctt atctttgggg
    12421 atagaaacat ctatattttt aagattgtgt atctttgctc cattaatttt tatttctttc
    12481 attggttcac ctcattttat caattttatc aaaccgtaaa atagggatat attaatcctt
    12541 aatacaagaa tagattaggt gaggttatta aaaaggttct ataggtaaat atatatcgac
    12601 aaagtgtcta ttttgagggt gattgtgtgg gttgttaaga tatacttcaa aagggaagga
    12661 ggcacgtagc ttataattac catttgatag ccattcatta tacataaaat cccacgcatc
    12721 actatattca gattttgaaa tatcaaaatg tcccacaaga tattttccag aagggattat
    12781 catattgcca agattgtcat tctctttgac aacaatgtta tctggaatgg tcatgcaaat
    12841 actagtcctt aattgatgct cctgtgtaaa ttgtggatta tcatgataaa tggctaatat
    12901 ttgtgtgttt tcaagtccaa gtagattctg ctcacttgca tatgtgaata accgttctaa
    12961 aagttttggg aaagtactgg ttagattacc atatgaacca gtatatctag tgtaaatagt
    13021 attcatatta tcaagttcta gaatttcaat ttcaccttta acctctctag tattcttaca
    13081 tttaggtttt gatatgcttc tattgtactg agaaatttta tatggttctt tgcaattctt
    13141 gctataattg tttctatatt ttatagggct tattttatag taatttttaa atgctctcga
    13201 gaaaactgct gaatcagtaa agccgaagta gtgtgcaata tcagtaacag tcatgtcagt
    13261 tcgatgaata agaaaagcag ttgcattttc tagttttagc ctatttacat attgtgccaa
    13321 agtttctttt tctattgctt tgaagattct atgaaaatga aattttgaaa aacctgctat
    13381 attagaaagt tcatcaagag aaagaggttc atgtaaatgt tcttctatat agtcttgcac
    13441 tttgcaaata cgatttagat attctttttt acttttagca tttgtcatat atagccctcc
    13501 ttattgtgta aaatgtgtat taattaattt atagcaatat agtaataaaa ttttatgttt
    13561 ttgcaattta tgataaataa gatagcgttt aattttttat aattgataaa agatatttat
    13621 aattaataaa agatataaga tgccttatat ttatttttgc atataagtat agtcttcgta
    13681 ataattagta taccatagtg atttattttt aattgtgtat ttatataaat acacaactta
    13741 tgatatggac gaattattat gcaaataagc tgtaattaaa taaattgcaa tataaaccag
    13801 ttgaaacata agttagggaa atattatcaa agttattatt tagcataaga gtatagaggg
    13861 aataaaataa gattaaaaaa ttacatacta aatttaataa aattattata ttaaaaataa
    13921 tattaagttt attgtttaaa taaaaaagtt aaatctacac tattaactta ttatacttaa
    13981 aactttaaaa tgaaaatatc aaagaatact ttttaataaa aataatcatt taataagtta
    14041 tttaaaaatc taaaaacttt acaacaaatt atctatttaa attggaggag tgggaatatg
    14101 agtaatagtt tttatcaatt aaattcagca gtattatatt ttaatgaaaa aagagatgta
    14161 aatagaataa ggtttaatca ctatgtaatg agaaaagaaa atatacaaag attaaaagga
    14221 actctgccaa gaggacaatt tatgatgaca gtaaggaaag ctgcatctga ccttgatgta
    14281 tctatatcta caataagtag acttgtaaat gaatttatag atttaggtat attgagatta
    14341 ataagtaggg gagtaaaggg aaattgttgt tctgtatata gttatgtttg ttctgaaaat
    14401 agtaatgcag aaattgtaac aaagaatagt gatattttca aaaatataga gaaatacatt
    14461 gatgcaacta ttaacaataa ccaaaaaaca atgaaatata aacatagaga tgagttgttc
    14521 aagaacagta ataccaacac atacagccgt ataaatcaag agagtataga caaagattat
    14581 gatttgataa ttcatactgg gtatgaaaca gaaaatgaga caaagaaaaa agaattatta
    14641 aaaaataatt taaataaaaa gaatttaaat aaaaatacct ttgaaaattt ggatgaagat
    14701 ttgactgaag attctactta taaaaatcca gaaagcatac atgaaattat tataagaaaa
    14761 ttaaatagtg aatcaggaaa aaattttaaa gctgatttga gtataactaa ggcacttata
    14821 gataaaagat taaaagaagg gtatagttta gaagattttt acaaggttat agaggcaaag
    14881 gtaagaagat ggagatatac agatatggaa atatatatag aaccaacaat tctgtttggg
    14941 tatgaatttg agtcgtattt aaatgaggag agttctttat ctgcttgtaa ttatggtgat
    15001 atgtgttatg aagatatgta ttgagatatt agttgctttt tagttgttta aaatatgttt
    15061 atatataaat ataaatagtg tattaaaatg gagttgtctc aaaatagaga gaagcctctt
    15121 cttaattgtt taaatgatga aaatatattt gatttaatac aaaggagagt gccttatgag
    15181 ctagaaagtt cattttgaga cactcacttt tttaatatac tggagaaata taacccattt
    15241 taatggcttt tgtaatagcc tcaactgatg atgaaacatc tagcttgtca tatatgtgtt
    15301 gtaaatgatt tgataatgtt ctttcactta tatacaattc atcagcaatt atttttcttt
    15361 ttttaccact acagataagc tgtaaaattc ttttctccat attagttaaa tcttcaataa
    15421 ttacttcagt attttcagat ggaaaacagg ttaccccttg atagactttt aataatgaat
    15481 caattaaact atcagggcta atattcttat ttaggaatcc atagatacct atttttttag
    15541 cctcatgttt ataaactggg aggtcgtatc cagtcaagat tattatttta atagttgaat
    15601 tagtctctaa taaattataa gctactttta agccatcaca ttcacttaag cctctaaggt
    15661 ttatatccat taagacaatg tctatttttt tatcttgaat catttctgaa agattatgga
    15721 tgtcctgtgt ggaataaaac tgttcgattt cttcgtattc ttctagtgca attgacaagc
    15781 ttttagcaaa aagcatatgg tcatcaacta acaaaatatt tataagaacc atctcctttc
    15841 atagggattg taatctgtac acaaactcca tgaggtatat tatcagaaat acttatcgtt
    15901 cctcctagat tttctacttg ttctttaatt gatataatcc ctttgtgttt tattatatca
    15961 aaagtaattt tagttatatc taaaggtgtt ttaaaagatg tatttttcac accattatca
    16021 ttaatattta attttattat atttttttct agtgctaaag ctatccatgc atggctacca
    16081 tttgaatgtt tatacacgtt tgtcaataat tctttaatca gtcgatatat caatatatca
    16141 tatggttcaa ctaagaataa agtatcagaa cacttaaatg aaacacaaat gtttttttgt
    16201 ggaaaggatg aagaaacact ttcaattaaa ttctgataat tttcttttac tgttaaattt
    16261 tttaaaataa caggatgata gtcttgcatt tgatttctta tacatgtatt tagattgtta
    16321 agtgtttcat atataatatc ttgaacttct gggcgatatg acttactcat catgtttttt
    16381 attgaaagca ggttctgtaa tatgtcatca tgtaaaaaat tagaaaactc tgtttttagt
    16441 tgttcttctt gttgtaattt ttctaatgca aaagtatact tgctattttt aactacttta
    16501 tttttttcat ctctaaggtt aaactccaaa ataatgttac agaggaaaat aagcataaat
    16561 aaaacattta tagctattaa tattatagaa aaattcccat tggcaaatag tacgaccaag
    16621 ctaattacta aaatacttat aaaaagaaat atagcccttt gttttatgtt aaaaactgtt
    16681 gaaataggaa aactatcatt ttctttaagt gcaataccat gaatactcat aaaaaatacc
    16741 aatacagtta gatagattcc aaaattacca atatgatttg atattcttag tgtaaaaaaa
    16801 taataagtaa ggaatcctat aattgttata aatactgaaa tcgatatagg ctttttttcg
    16861 ctttttatga caaaaacaac ccttttcaaa tgataaaaaa taatatataa aaagcttatt
    16921 atactaacaa caaactgtat tccgtacata caagcatacg ttctgttaga aataaatgct
    16981 cctacaattg caccaatgca ggtgataagc aataaaatat ctgttatctt acggaaattg
    17041 tatccactac cttgaaacaa aaataaaaat ataaatttaa tagagacata cactataact
    17101 gtgcttaata ttttaaaaat aatagtgcct attggtgtgg ttacaaatga taagagtaaa
    17161 taccaactgt ctagtgctag taatccacaa aataatgaaa taatgttatt ttctcggaca
    17221 ttacaagagg ttatatatgt gatgtctatg agtaataatg ttgaaattat taagggaata
    17281 atgctttgga tattcatata agtttcagtg cttgtagata ttcccatgaa gagaagtgat
    17341 agaatgtagt ttcctaaaaa tagtattttt aaattaaaat ttgtcaatct tatacacctc
    17401 cttatgagtt aattatatta attttatgac taaatcaaac ctaagaatct ataattttaa
    17461 attatatcaa atacttataa atgaagtata ccaaatcgtc acacctctaa gcttgacgat
    17521 ttggtaaata ttaatttttt aatacaattt tacaacagga tttaatagta agtatataat
    17581 atatcaaata cactacagaa gttaagaaaa ttgcaataat cacaggtatg tattgtgaaa
    17641 atgaatttcc aagtaaattc tgcatcaaag cagtcttata aaccaaggta gcaaatatac
    17701 agtccaatat accaagtaaa aacggaatat taaaaaatgg caatacttgt tttttaataa
    17761 tttttttaat ttgtatatta tcataaccca ttttctgtaa aatcttataa tcagatgttg
    17821 aatctgaaat tgctgatata ttgttaaagt ataaaatact tccaacagca ataaagaata
    17881 ataccacaag aaatccgatt aacagaaatg tagaactatt aattgataat aaatcattta
    17941 tcctgtgaga atatccttgt aaataagggc ttccatctaa ataatctgaa atattactat
    18001 ataaattttc attattttta attgatttac cattaatact taaaatgctt gtcattggta
    18061 atttattttg tgctatttgc tcatatatac tatcattaac gataagtgtt ccaacgctat
    18121 tggcaaaaga aatagcattg tttaatgatg tttcccttac agctacaggt gtttctttac
    18181 cattaataag taatggataa atcgttccat tttcactata tccatcatta tttggttgat
    18241 atttcattaa aatacattca ttatccctta aaggggtaag ttgttttagt agctttgttc
    18301 gattttgtgc ctttaataaa gtataataat cagaaaaaga tatacattca aatcctgatt
    18361 ctcttgaaat aacttcttta gaagaactac tattagataa attattctta gatgtaccaa
    18421 tttcatattc aaatggaagg tcttttgatg aagattttac cttataaata tttgtctgtg
    18481 taaaaataat atcatctgta ttagacgtat attgactgac aatttgtttt acatcttcta
    18541 tttgtttatt tttttctact ctaaattcta tctctgaagg tgcaatacgc gaaacagatg
    18601 caatagggta gtataaggac agtgccataa cacttgaaac tgtcaaagta gtagcagaga
    18661 gtaatgtaag cataattaga gttttagagt ttgaacgtat acgatagata aagtttggaa
    18721 tagctattat cttcatatct gtgtagaaag tacgtttatt ttttttactc ttttgcataa
    18781 tatatggaag aaaggaattg ataaagagaa ctgtaccaat tacaatgata atcatagtta
    18841 tcaagcccat ttgataaaat ccaatactta cccatactga tttagctcca cgaagaatat
    18901 ctagtgataa acaataccca cttaaaatca taataaatcc cataaaggct ggaatttttc
    18961 tgaactttaa ttttttttct gcactttttt catgtcttat caattttaca agtgaagtct
    19021 tataaagaaa tttaccattt gatatagcta agactaaaac aactaatgct ataaagataa
    19081 ttgttttgtt tattgcattt atattaaaaa atggtatctg tgaattatca attgataaat
    19141 taagtagtgc tgtaattcca aagacaatac ccttatgtga caatgctcct aataccaatc
    19201 cagtaataaa agctccacta caaattaata cattttcaaa ggtaagtagc gataatattg
    19261 taaacttacg atagccaagt aaagcatata tgcctaattc ttttgtacga cgtctcaaga
    19321 agaatcgatt tgagtatgcc atatagaaga tgacaaatgc catcaaaaat atcgaaataa
    19381 cattacacat agattcaact ctaccatcag ttgaaatttt ttctagcatt atcttattaa
    19441 cagagaatga agtaaatgcg aaaaatacag taataacaaa agagactgaa agtagatata
    19501 gagaatagaa tgaaaagttt tttttaagat tctttattgc catataaaaa atgttcatta
    19561 aattatcctc ctatctttta gtatccaatt ttgcaatttc ttgaataatc aactcataaa
    19621 atgtatgtct attattcggt tgtttattta attctttaat gatatgacca tctttaaaaa
    19681 tcaaaattct atttgcaaaa cttgctgcat aggcatcatg tgttaccatt aaaattgttg
    19741 ttttcaactc ctcatttgct tcctgtagtg agtggagtag ttcagtagct gaattagaat
    19801 ccaaagctcc tgttggttca tctgcaaaga gaatactagg atgttttact attgctctaa
    19861 ctgctgaagc tctctgcctt tgcccaccag ataattcatt tgggtattta tttaattgag
    19921 aagctatgtc aaatcgttca gctagactct ttaccatgtt ttctatttta tctggattga
    19981 gtttctgaag tgtaagaggt actgaaatat tctcgaaaat tgtaagacta tctagtaaaa
    20041 aatactcttg aaagataaag cctaaattat ccttacgaaa atcagcagca caagtgtcat
    20101 taagcgattt caaatttata ttatttatga aaatatctcc acttgttggt ttatcaattg
    20161 tagataatac attaagcaga gttgttttcc cagagccaga agctcccatt atacctataa
    20221 attcaccttc tgatacatta aaggatacct tatctaaact cggctgttgc cctttattat
    20281 aagttttagt tatgttattt acttttaata ttgtattcat tgtatatgtc tcctttcgtc
    20341 ttaatatagt caaattatat attaacctta ttgtttcttc atgagtaaat cacgcaataa
    20401 ttctacacaa attacttata tcacaatata ttgtttaaaa tctaacttta ttaggtttgg
    20461 gatgatggac aagattttaa tttaaaagag tgcatagata tataatggca taatgtagat
    20521 ttaaattaaa aaaaataaaa taaagccata aatattgaaa aattcaatat ttatggcttt
    20581 attgcttgta ataattaata gaatatatat tttttattaa tcatctattt caaattctaa
    20641 tattttacca gtaattgcat taattgttat ctcatattca atttttcctt ttattatttc
    20701 accttcatat tctttgtcat cttcatcata cttaaatttt actattttcc caccaggcac
    20761 tttatctagc attattgatt tagctttttc agcactaata atagaactgt tgtcattagt
    20821 attagagtta ttcttatcat tatcatcaaa gtcatcatca gaatcattgt ccatgtcaat
    20881 atctacaatt cttccatcaa atgcacttat ctctaattca tatgttttct tattttttat
    20941 tactttagcc tcatattcgt tatcttcagc atcatattta caatagatta aattaccatt
    21001 aggaacagca tctaatgcta tagacttagc tttatccaat gatatatttt gtgtacctaa
    21061 attattatca tttaagtcat catctttttc aatttctatt attttaccag agtaggcatc
    21121 aatttctatc tcatatagga tattatcctt tataactttg cagtcatatt cattatcatc
    21181 ttcatcataa taacaaacta aaatatcgct tcctggaaga gcttgtttta atatttcttt
    21241 agcctgtatt aaagatattt ttttagtttt atttcttatg ttcacatttt ttagttttaa
    21301 aatatcttca aatgcttttt gattatatcc tcctcctact tgtgttattt catctatatc
    21361 tttattttta ataaattcct tttgactatt tacaaggcta ccattagata tcattatagg
    21421 agaattttct ttagcagcta atactcctat tgataatgaa tctactaatg cattttcttg
    21481 gttaatacca tctttagcta caaatacatt atttattttt ttatctttat aaaatttatc
    21541 aataattttt gcattagtat tgtttctatc tgaaccactg attctttctc tgtttggata
    21601 tttctttact gtattgtctg ataaaatctt atttcctcca actatgtaag atttttttat
    21661 agacctattg tttaagaaat ttatactact atcattgctg ttttcatctg atactaatat
    21721 tataggcata ttatgtattg ctgctggaga agctatacta actgcatcag ataatccctt
    21781 tagtccattt acaactgcaa cattttctac cttttttatc ttatctattt ctttaagtac
    21841 atttgtagac attttatata tattgtttcc tactatttta tttattttta tgttaagtga
    21901 ttttatttca ttttctactt tagaagaaat gctatttcca ctatctacaa tgtacacatt
    21961 atctacacca agccttttaa gctcagcctt agttgaattt tcaatactgt tgttgtttac
    22021 taaaagtata ggtgcattct ttagcttagc aaatggattt gcacaaagcg cactttgaat
    22081 agaattacca ttaactataa tggctgtttt tgattgaacc catcccaatt tacttacttc
    22141 tactgctgtt tcatatcttg ttttacctat taatctttct tgctttgtag tattgtctgc
    22201 aaaaattgct gaagaactag aaaaaaacat catacctgat attaatatag ctaaattttt
    22261 attattcata tttttacctc acaatcttta aaaatttgtt atttagcata cttaataaaa
    22321 tataatctta aaatcaaatt gatactgagt ttgaagttac aaaatcaaca aataagattt
    22381 ctttaataca aaattttcct ttttatattt aacattgtat cacaaatata aaaaggaaaa
    22441 aactttttaa aaagggtata cactattcat tttttatctt ataaataagt ctttaccact
    22501 gttttatata ttttaaaata gacacaagac ctatttctaa atcttttata aatattttag
    22561 gtgaaatttc tttttaaaca tatctaaaaa gtatttgtag taatattaat ggactgaatt
    22621 tcttaaagta tatatttctt tgcatgttgg agtttgtgaa gtttgagaat tggagggtga
    22681 aagaaacatg caatggatta atattaaaga actgtatttt tataatattt gtcttaaaaa
    22741 taaaaaaatc tattgacttg aagttaactc caagtagtaa agtataatta tacaagaatt
    22801 atatacttgt aagaatagtt aaagtagaga gaaaaaacaa acaagtttta aagggggaag
    22861 taaaacaatg gaggcaaaaa aattaggatt tggattaatg cgtttaccaa taaaagatga
    22921 aaatgatgtt acaactattg atatggaaca tttaaataaa atggtagaca cttttttaga
    22981 aaggggattt acatattttg atacagccta tgtgtatcac atgggaaaaa gtgagatagc
    23041 acttagagaa tctctagtaa aaagacacaa aagagagagt tttactatag ctacaaaact
    23101 tccattaatg gctttaaaga aaaaagaaga gcaagaaacc atttttaatg agcaattaga
    23161 aaaatgtggt gtagactatt ttgactacta tcttttacac aatataggcg tgtcacatta
    23221 tgaagtagct aaaaaatttg atagctttaa gtttattgaa gaaaagaaaa aagaaggaaa
    23281 aataaagaat attggttttt cttttcatga tagtgcagaa ctattggata aagtcttgag
    23341 tgagcatcca gaagtagact tcgtgcaatt acagattaat tatttagatt gggataatga
    23401 aagcatacaa tctagaaaat gctacgaggt ggcagagaag cataataagc ctgtaattgt
    23461 tatggagcca gtaaaaggag gtacacttgc aaagatacca gaaaaagcag agaaattatt
    23521 gaatgactac aatccagata tgtcaatttc atcttgggca atacgttttg cagcaagtaa
    23581 agataatgtt atgatggtct taagtgggat gtcaaatatg gaacaattat tagacaatac
    23641 aggatatatg caaaatttca aaccattcgt acaagaggaa tataatatta tagatgaagc
    23701 agtagagatt atcaacgaat caattttagt tccttgtact gcctgtcagt attgtgtaga
    23761 aggctgtcca aaaaatatcg ctattccaaa ctattttgcg ctgtacaatg cagaaaaaca
    23821 agctcttaat actggatttt caacacagat ggtttactat aataattata ctaaaactta
    23881 tggaaaggcc tcagattgta ttgaatgtaa acaatgtgaa gaaagctgtc ctcaacacat
    23941 taaaattata gatgctttaa agaatgtagc agaaaccttt gagaaataat tcaatctata
    24001 caatatcaag aggagaagat atgtatgacg atttcagaag ttagtaaaaa atacgagctt
    24061 tcagcggata ctttacgata ttatgaacga attggtttaa taccacctgt aaatagaaat
    24121 aaaagtggaa ttaggtcttt tacagaagaa gattgtgagt gggttaattt cataaagtgt
    24181 atgagaggtg caggtctttc tattgagaca ttaattgagt atgtagctat gtttcaacaa
    24241 gggagcagta ctatcaaagc tagaaaagaa cttttaatag agcagagaaa ccaactagca
    24301 aaaagaatag aagaaatgca aaaaactttg gaacgattaa attttaagat tgatagatat
    24361 gaagaaggta ttattgagaa agaaaaagta ttaaagagca gtagaaataa gaaaatggag
    24421 gcagtatctt atgagtaaaa atgtattaat agtatcagct agtcctagaa aaggtggaaa
    24481 ttctgactta ttgtgtgacc agtttataca aggggtatta gaatctaaaa atcaagtgga
    24541 gaagatattt ttaaaagata aagatattaa ctattgtact ggatgtggtg cttgttatga
    24601 aaaagaagca agttgttcac agacagatga catgggagaa attcttgaaa aaatgattgg
    24661 ggcagatgtg attgttttag cgactcccgt ttatttttat actatgaatg cgcaaatgaa
    24721 aactatgatt gatagaactt gctctagata tactgaaatt tgtgataaag atttctattt
    24781 tatcgttgca gcagcagatg aaaatgtggc tgatatggaa agaacaatag aaggatttag
    24841 aggatttaca tcatgtctaa atggttctaa agaaaaaggt atagtatatg gtgtaggtgc
    24901 ttggaatgta ggtgatatta agggaagtaa ggcaatgaaa caggcatatg aaatgggtaa
    24961 gttggcttag tatgtttgta taaaattgta taaaatcgaa tatattctta tcatttcaac
    25021 aataaaaaga ggcttatcta tattttgaga cagcctcttt gtgctatatc atttattttt
    25081 attctatatc cttattatac cctttatttt tttatgccta tttaagtatc tgttgttact
    25141 catatatttt aataattacc cttaaaaaac tatacagatt cctgcataat attattttct
    25201 ttagtaatta atttttctag gtttttccaa tccatttctt ccatatttgc aaaataatga
    25261 ccacttccta tgcaagtcag ataagacttt ccatctaaat caaacgaaga acctccaata
    25321 cactttgaat tacatttctt acaagtacga gttttagtta tactatcttt aatagtttta
    25381 gagcattcct ccacagcatc tttatatgta tttagatgaa aaagatttgc tttaactctc
    25441 catttttttt cattacattc aatagtaaat aagctacgtt ttggtttctt agttgaatat
    25501 actattttgt aagaacgagc acctgttttt ggttcaattt tacaatctaa tgatttacca
    25561 agttcatgta aatgacatgc aatatcataa tctttaccac ttagtacttc taacatttct
    25621 tctgttgttt ctgccgttaa ttcacttttg ctcatattaa aaaaatcccc ctatataagt
    25681 aataatttca catgaaaata attaatataa gtatattaaa taaaactatt aaaatcaata
    25741 aaattactac aatcttacat tattgggcat agaatgagag ctaatgattt attagaaata
    25801 agacttaata gtatgaaaat ttacttagac gtggtacaat tctataaaag atttaaaact
    25861 aggaaaggag aaagttgttg agatacggcc aatataacaa tttatttata agttgtaaat
    25921 ttattatgag attaattaga ttgttaagta atactatcaa aaggtagttt tttggatttt
    25981 cagcaacagt ggtagatatt gataattttt tggttattat tatatttagc tgttatattt
    26041 tcaataggct ctatgataac tagggtaaat aaggtatggg taaaggtttt attatttata
    26101 atagtgggat tgtcaactat agttctttca tatgtaataa cttgataatt taagattgaa
    26161 aaataacttt aatctgtaaa ttctcaaaac aagaattctc atgttggtaa atttctagat
    26221 atgagaaaaa aattgacatc ataaaaaagt aattttaaag cattttttta cgaaaaaatt
    26281 cagaagtaac tattttgaat gacttcacaa aattttatat ataaataaag tttggcacgt
    26341 taattgcttt aataaaagtt aacaagacac aaataaacat aatcatctaa gtattgatta
    26401 tttgaagttt tagatttgaa atttaatcta aaggttcgta ttaatattgg tgtttaggaa
    26461 attttatttt cctgtaaata taacttaata ataggaggtg aagtcatgtc aaaagtagta
    26521 atagctacag agaaagctcc aggagcaatt ggaccatatt ctcaagcaat tcaagttgga
    26581 aacatagttt ctacatcagg tcaacttcca atagatatga agactggcga gttagtatct
    26641 gacccaaaag aagcaacaaa agcttcttta gataatgtaa aagcaatatt agaacaagct
    26701 ggtacaagta tggataaaat atttaagact acagtattcg taaaagattt aaaggatttt
    26761 aatgatatta atgaagtata tgctacatat tttaaagaaa atccaccagc aaggtcatgc
    26821 gtacaagttg ctcaattacc aaaagatgca gttttagaaa ttgaagcaat ggcagtatta
    26881 taagtattat aacaataaaa ccaataacaa aactaataaa aattaaaaac taataaaaaa
    26941 agtctacaat taaaaaagtt tatattaaaa aagtctatat aaaaatctat ctaaatattt
    27001 aactattgag cttttctcat ataatgtata tttttatgtc aaaaatatat ttgttatatg
    27061 aggaaagctt tttttatttt attattgtat tgtgatttac tttattgtct gtatcttata
    27121 attaagtaat taaggtcatc atataaaaca aactttttat aaattaatat tgtgtgtttt
    27181 aatgtaaata tataaataag taatgtttta tatatatttt aaagagtgac tatatgttaa
    27241 aatatagcta aactgataat ttggtaaatt aaattctaat gggggaaact atgttaagta
    27301 aattaaaaga atttcaacaa gaaatgataa aatacactga aacagtagct agtgtgttag
    27361 atgtagatat tgaaatagtt gatgatagat taataagaat tagtggtaca ggtctgtata
    27421 aatcaaagat aaatgaaagc gttgttacag aaggatttat ttacgacaat gttatacaga
    27481 caggtcagga attagtcgta ttggatatat gtgataatca gctttgtata gaatgttccc
    27541 attacatgaa atgcctaaat aaagtaataa tagcagttcc aataaagtat aataatcgaa
    27601 ctataggagt aattggtgct attagtacag ataaaactaa aaaagtagaa ataagtgcaa
    27661 aaatagataa ttatttaaaa tttgtcaatc atatatgcga tttaatttct atgaaaatag
    27721 aagaacatga agcgtcaaaa aatagcagta gaaaaatgga tatgatgata gaaatcattg
    27781 aaaatgttga aaaaggcgtt ataatactag acataaatag caaaatatct tatataaaca
    27841 atatagctct aaaaaaatta gatatatata aaaatataat agaaaatata gtatctgttg
    27901 aatcttcctc aaatggacat gaattactag aaattgatat tgataacaaa atttataata
    27961 taaatgccaa aataattccg gtatatccat atataaatca atacgacaaa ataataatat
    28021 ttgacaagac atatatcaat cataaaggac atggaaaagt caatagtggc tggggaaata
    28081 gtgatataga gtctataatt ggaaattcag aggcaatgtt aaaagtaaaa gagagaacta
    28141 agaaattagc aaagtcaaat tcaactgtac ttataactgg ggaaagtggt acgggtaaag
    28201 agctaattgc tagggctata catgctgaag gtagcagatg gaacaagcca tttattgcga
    28261 taaactgtgc tgctattcca gaaaatctcc ttgaaagtga gctatttggc tatataaaag
    28321 gtgcatttag tggagctagt agtggaggta aagtaggtaa atttgaactt gcaaatgaag
    28381 gtgttatatt tcttgatgaa ataggagatt tgtcaatgcc tttacaagca aagttactta
    28441 gagttttaca agagagaaaa tttgcgagaa ttgggtcaaa taaacttata gatttagata
    28501 taagagtgat tgctgctaca aataaaaact tattgaaatt agtaaatgaa ggtaagttta
    28561 gggatgattt atactataga ttaaatgtaa ttcctataaa tttgccacct cttagggaaa
    28621 gaaaggatga tattgaggca ataatgatga agtttgcttc taaatattct ttagaattag
    28681 gtattcagtt aaataaaata gaagaaaatg taatgaatat gttgattaac tataattggc
    28741 cgggaaatat aagggaactg gaaaatgcag ttgaatatat gatgaatttg gttggagatg
    28801 atggaataat atataaagat atgcttccat tggatatttt aaattattat aatattaatg
    28861 gaaatgtttg taaaaataag gatataaata taatatttga agatgacata gttggaggga
    28921 tagtagagaa tcaggaaagg atactttcaa ttaaagaatt agagttgact tacataaaca
    28981 agttgttgaa taagtatgga agagatacaa agacgaagaa gaagatagca aaggatttag
    29041 gtataggttt ggctacacta tatagaaaat tggaagagga acagtagtaa tataatatta
    29101 aaatgatagg tatttgtgtg tttttataga taggtatttt tactttatgg tggaggtgtt
    29161 attatgcaat atgcgataga gctatattat gataaaaaaa cggaaaagca actttttgat
    29221 ttatctaaaa aaatcgctga tgaaaaaatt agtacgaagt acttagaatg gaaaacaaga
    29281 cctcatctta ctttggcttg tttcaatgat gtggatgagg cttgttgcat agacaagcta
    29341 aaggggtttg cacaaaacca taaggtaata cctgcttaca ttggttcagt aggcatgttt
    29401 aatgatacta aaacggtgtt tgtatcacct ataatgaata gcagtatgta tcagtttcag
    29461 agagaattat atgaggtact acaagatttt gattcaaatg gttgggaatg gtaccacccc
    29521 aatcgttggg taccccattg cacaatagca cttactggag atgatgaaag tgaggctttt
    29581 tttcgggcaa gtgatgtatt actgcgtgag ttcaaaaaaa taagtggtga gtttgtctca
    29641 ataggattgg ttaaaattac atttcctgtg gaagaaattt ttacagtgaa tatgaatagg
    29701 taactttaac tctgttgtgg atgttatgaa tattttgcat agtgcatttc atcagataaa
    29761 tgcgaagttg cgaatttcga cagctcaata gtcgcaagta ggacacaatg gtacacatat
    29821 tgcacttttg cttattggag ggacgcccat gtaaacttct gtaagaagct atgaaaagat
    29881 ttaagccatt ttggaggctt tgggtaataa agaatatttg ggtaataaag aatataaagt
    29941 atataaattt atagagttta tgcgtaagaa ggttatagcc atatatttat agaaaataaa
    30001 agtagtaata tatctgacaa aacaatagac atataaaaaa taagagcata ataaaggaag
    30061 aattaaaata aataaacgat ttctcgaatt gataattctc gtattgataa aaatttccca
    30121 atatgagaat tttttctttt ataaatctta tttttcacat ttaatattta taaaattcaa
    30181 agaaatttta taaatatatg taattccaac ataaaaaaat tgtttttaga ataaataata
    30241 ttggcatagt aattgcttca ctataagaca caaagataaa aaattaaaat gacaccgaaa
    30301 aatttgaaag gggaatataa aataaatgag agaaataaaa tggaaattaa ataacttacc
    30361 taaatcagag gaaaaagaaa aaggaattga gtttttaaga gatgaagaaa ttgcaaaggc
    30421 taaagctttt catgagagct ttccacaata tgaaaaaact cctttagtta aattagataa
    30481 cttagcaaaa tcactaggcg taagcggaat atatgttaaa gacgaatctt atagatttgg
    30541 tttaaacgca tttaaagttt taggtggttc ttactctatg ggtagatact tagctcaaag
    30601 attagataca gatatatctg agttagggta tgacaaatta acttcaaaag aaataaaaga
    30661 aaaattagga gaaataactt tctttacagc cacagatgga aatcatggta gaggagttgc
    30721 ttggacagct aataaattag gtcaaaaatc tgttgtatta atgccaaaag gttcttctga
    30781 atttagatta aataaaatca aaggagaagg tgcagatgct agtataacag acttaaacta
    30841 tgatgatgca gtaagattag ctaatgatta tgcagaagct gatgaccatg gagtaatggt
    30901 tcaagataca gcatgggacg gatatgaaga aataccagca tggataatgc aaggatatgg
    30961 aactatggct aaagaagcta tagaacaatt aaaagaatat ggagtagata gaccaacaca
    31021 cgtatttgtt caagcaggag ttggttcact tgctggtgca gttcaagggt atgttgcttc
    31081 aatatatgat gaatgcccaa taacagtagt agtagaggct gatgaggctg attgttacta
    31141 taaatcagca gaagctggag atggaaaacc aagatttgtt ggaggagata tgccaactat
    31201 aatggcaggg cttgcttgtg gagaaccaaa cactataggt tttgaagtgt taaaaaatta
    31261 ttcatcagca ttcgtttcag caccagactg ggtatctgct aaaggtatga gaatattagg
    31321 aaaccctcta agaggagatg agaaagtaat ctctggagaa tctggagcag ttacaactgg
    31381 agcattagtt tcaatccttg aaagtgaaga tttaaaagac ttaagagaag ctttgaaact
    31441 agatgagaac tctaaagtat tattaataag tacagaagga gatactgacc ctgataaata
    31501 tagagatata gtttggaatg gtgaatgcca aagtaaataa aagacttaag gaaaataaaa
    31561 acttaacaaa taaatgaaaa atttaaggaa aataaaaact taaataagtg aaaactttaa
    31621 ataaaataaa aactaaaaca aatgaaaaat ctaaataaat gaaaaagtaa agcaaatgaa
    31681 aaattcaaaa taaaaactaa ataaaattaa ataaaaccaa ataaaattaa aataaagtct
    31741 aaataaaaat ttaataaata aaatataaag aaataaaaaa tcaatagatt aagtgaaatg
    31801 ctaataaatt aaaaaagtga aatatcaaaa taaaacgtca acaaattaaa aattatatgg
    31861 gggaatatca aaatgttaaa tgaaacaaga aaaaaacaat taactgaagt atgccaagac
    31921 ttaataagaa atgctagtta ttcaggtcaa gaagaaaacg tagtaaaagc tatagaagaa
    31981 aattttgctt tactaggttt tgatagttgg tcaagagata gatatggaaa tatagtagga
    32041 tgtataaaag gaaataaacc aggtaaaaaa atattatttg acgggcatat agatacagtt
    32101 ccagttccag atgcaagtaa atggagtgtt cctccttttg aagcgagaat agtagatggg
    32161 aaaatatatg gtagaggaac ttctgatatg aaggggcaag taagtgctat gatggctgct
    32221 gtttcatact ttgcagaaga tactaacaaa gactttgaag gtgaattgta tgtagcaggt
    32281 gttgttcatg aagaaatatt tgaaggtgtt tcagctagag agataagtaa ggctgttcaa
    32341 cctgattatg ttgtaatagg tgaatcttca gaattaaact taaagatagg tcaaagaggt
    32401 agaggagaaa tagtagtaga aacttttggt aaaccagctc actctgctaa tccagaaaaa
    32461 ggtataaatg cagtttataa aatggctaat gtaatccaaa agatacaaca attagtacct
    32521 ccaactcatc cagttttagg tgatggaata ttagttttaa cagatataaa atcttctcca
    32581 tatccaggag catcagtagt gccagattat tgcaaagcta cttttgatag aagattatta
    32641 gttggagaaa caagagaagg cgtattagct ccaatacaag ctttattaga tgaaatgatg
    32701 aaagaagacc cagaattaaa tgcaaaagtt tcttatgcag ttgaaaaagc tgattgctat
    32761 acaggaaata ctatagaaag tgaaagattc ttcccaggtt ggttatatga tgaagaagat
    32821 gaatttgttc aagcagcgta taatggatta aaagaagctg gaatagattc agaaataact
    32881 caatactcat tctgtacgaa tggaagtcac tacgcaggtg aggctggaat aagaactata
    32941 ggatttggtc cttctaagga aaatcttgct catacaatag atgagtatat agaattagac
    33001 caattattca aaggtgcaga aggatattat ggtatattaa aatcagttta taaaaaataa
    33061 ttaggagatg gttttgtgag aactttaata aaacatgggc ttatagtaga tggaaataaa
    33121 acaccagcat atgaaggaga tattttaata gaaaacgaga aaatattaaa aatatcacaa
    33181 gatttaaacg aagaagctga caaagttata gatgcaaaag gtagagttat atgtccaggt
    33241 ttcatagata ctcatagcca ttcagaccta gttattttag ttaatccata taatgaggta
    33301 aagattagac agggaattac aacagaagtg ttgggccaag atggtatatc tatggcccct
    33361 ctacctcaag agcatatatc ttcttggaga aaaaatttag caggtctaga tggtgaaagt
    33421 gatgaaattg attggaaata tgaaacaaca gagaattatt taaaaatgat ggattacaat
    33481 ggggtaggtt taaatgaaac ttatttagta cctcatggaa acgttagaat ggaagctatg
    33541 ggacttgaag atagacctgc tactaaagaa gaaattcaaa aaatgtgtga aatcacagag
    33601 agagaattaa aagcaggagc tataggattg tctactggac ttatatatat accttgtgca
    33661 tactcattga ctgaagaaat tatagagatg tgtaaggtag tagcaaaata tgacggagta
    33721 tttgtagttc accaaagaag tgaagcagat acaattttaa cttcaatgga agaaatcata
    33781 gaaattggaa aacaatcagg agtaaaagtt catttttcac attttaaggt ttgtggtaaa
    33841 gcaaactgga agtatatacc acaagttata gagcttttag aaaaagcaga aaaggaagga
    33901 ataagagtat cttttgacca atatccatat gcagcaggaa gtacaatgct tggagtagtt
    33961 ttacctcctt gggcacattc tggaggaact gataagttaa tagaaagatt aagcgatgaa
    34021 aacgaaagag caaaaatgaa aaaagatata gcaaatggaa tagaaggctg ggataatttt
    34081 atagaatttg ctggaataga ccaaatattt gtaacaagcg taaaaacaga aaagaataaa
    34141 gatacaattg gtaagagctt attagaaatt ggaaaaatga gaggaaaaga cccattagat
    34201 gcaacgtttg atttattaaa agaagaagaa aatgcagttg ggatggtaga tttctatgga
    34261 ttagaagaac atataatagg attcatgaaa agagacgagc aaaatgtgtg tacagatggt
    34321 cttttagcag gtaaaccaca tccaagagct tatggttctt tccctaaaat actaggaaga
    34381 tatgttagag agttgaatgt actaacaatt gaagaagctg tttataaaat gactaaaaag
    34441 gcagctacaa gctttagtat aaaagataga ggcgaattaa aagaaggata ttttgcagat
    34501 atagttatat ttgacaagga tacagttagt ggttgtgatg attttatcaa ctctatgcag
    34561 taccctacag gtatagatta cgtaattata aatggaaatt gtgttgttga agaaggaaaa
    34621 tacaataaaa ttaaagcagg aaaagtactt aaaaattaaa tcttagcttt aaggaggaat
    34681 aaatttatga ttttagtggg gaatgggagg ctaataagcc aagattcttt aaatccctat
    34741 atggaagatg gatgtgtagt aataaatgat aatctaattg aagatatagg tactacagaa
    34801 gaaatgaaag ctaaatatcc agtacatgaa tttatagatg caggcaagaa aataatcatg
    34861 ccgggtctaa taaattcaca tatgcatata tacagctcat ttgctagagg aatggcagtt
    34921 ccaggaaaac cttctgagaa ctttttagag atactaaata atttatggtg gagacttgac
    34981 aaacagctta cactggaaga tacaaaatac agtgcatatg caacgtatat agaatgcata
    35041 aaaaatggtg taacaacagt ttatgaccat catgcaagtc caaatgcaat tgaaggcagt
    35101 ttgtttacaa tatcagatgt tgcaaaggat ttgggaatta gaacgtgtct ttgttatgaa
    35161 gtgtctgata gagatggtgg aaatacaatc caacaaggta tcaatgaaaa cgtaaacttt
    35221 ataaaatacg ctcaaaaaga tgatacagac atgataaaag gaatgtttgg gcttcatgct
    35281 gcatttacac tatctgatga tacattaaat aaatgtgctt cagagatggc tggtcttgat
    35341 acaggttacc atgtacatgt tgctgaagga ctagcagact tacaatataa tgtagataaa
    35401 tatggaaaaa gggttttaga aagattcaat gattttggag tactaaaaga aaaaacaata
    35461 gcagttcatt gtatatatat aagtgcagaa gaaatcagtc ttttaaataa aacaaataca
    35521 tttgtagttc ataatccaga atctaatatg ggaaatgcag ttggatgttc tcctgcaata
    35581 gagttattaa aaaggggagt tacagtagga ttaggaactg atggatatac tagcgatatg
    35641 tttgaatcat taaaagttgc caatataatt cacaaacatc acttaaaaga cccaagagtt
    35701 ggatttgaag aatcacaaac aatgttattt gataacaata gaaaaatagc taaagcttat
    35761 tataaaaatg acctaggagt acttaaaaaa ggtgcttatg cagatgttat agtagttgat
    35821 tatataccac atactccatt gacagaaaat acaatagggg gacacactat ttttggaatg
    35881 agtggaagaa gcgtagatac aactattata aatggaaaag tacttatgaa agatagaaag
    35941 ttaataaaca tagatgaaga aagtattcta gcaaaaagta gagaattaag tcaaaatcta
    36001 tggaatagaa tttaaataat tgattatgca aaattctatg aagcaggaac cctgtgactt
    36061 tagtcatggg aggttcagat taatatacaa gtaagaaaca agaatttaga tgttaaaaac
    36121 agagcttaaa caaaaatagg aatttaaatg aagtatataa ataaaaaata tacggaatag
    36181 aatattaaat taaatataga agggagaccc aaaatgtctc aagataaaag ccctaaaata
    36241 gctccagtag atgaaaggtt acctgtatcc aaatcttggg tattttcact acagcacgtt
    36301 ttagcaatgt gtgcaggagc agtagcagtt cctatgatga taggaagtgc tgcacgacta
    36361 gatcatgcta gtattgtttt tttaataaat gcttgcttgt ttatggcagg tataggaaca
    36421 ctcatacaaa gtgttggtat aggaaatatt gtaggtgcta aaataccagt aatagaagga
    36481 actagttttg ccgctgtggc aggtatgaca gcaatagcct catcatatag tgattcacaa
    36541 gttgcaatac agacagtatt tggctctgta atagtagctg gattgttttg tatattactt
    36601 gctccagtat ttgaaaaatt aataagattt ttccctagtg tagttactgg aacagttgtt
    36661 atggtaatag gtatttcact atttccagtt gggataaaat ggataactga caacaaattg
    36721 gaagcggttg aaccaaactc attagcatta gctttagcag tattggcaat aactttactt
    36781 tcatttaaat tcttaaaagg aatttggaat agcacagcta tattggtagg tatagtactt
    36841 ggtacactac tttccatggc agttggaatg gcagatttta gtgcagtaaa tggagttggt
    36901 tggcttaact taaatgtacc tttaaaattt ggaatgccta gatttgaacc atctgcaata
    36961 ctatcattgt gtttgattat gttggtactt atgacggaat cagttggtaa tatgatagct
    37021 attcatgaaa tggtagacaa agaagtaaca ggtaaaaata ttaaaagagg tctatttgga
    37081 gatggaatat ctacagcatt atctggaata ttcaattcat ttccaataac tccatttggt
    37141 caaaatacag gaatagtagg tcttacaggt ataaaatcaa gatttatagc agtttacgca
    37201 ggggttatat tgctagtact tggattctta ccaaaatttg cagcaataat aggagcaata
    37261 cctaagcctg ttctcggagg cgtaggattt gcaatgtttg gaatggtaat ggttggagga
    37321 gtaaaaactt taagcaaagt gaaatttgat ggaactaaaa atggggttat agtagcagtt
    37381 agtgttggtt tgtctatgat accactaaca aatcccgatt tctatcataa tttcccaact
    37441 tgggtacaaa caatattcca tagtggaata acaacaggta gtttatcagc agtgctttta
    37501 aacatattct tcaatgaact aggttctaaa aaagaaaaaa ataataaagt tgaagaagca
    37561 aaataaaaat aaaacaagta aaaatctata ttgacttaaa gtcattaagc attaataaaa
    37621 ataattcaga gatattaata attcaacaaa actatcttat attttaaata atataaaaaa
    37681 gtaaataaat aacgaataca aataaaagaa tacaatctaa atattaaaaa tatttaattt
    37741 aagggagaga taataatatg gctaatttaa aagttaattt atatggaatg gaatttttaa
    37801 acccaattat gacagcggca ggacctggag caaaagatgg tgctctctgt caagaggcag
    37861 caaaaggtgg agcaggagct atatgtacaa aaactatatc tgtattacca gctgatgtac
    37921 caagaccatg tatggcaaaa actaatagtg gttttttaaa cacagaatta tggtcagagc
    37981 ttccaaaaga gcaatggata gaggaagaat acaaaaaggt aaaagaaaca gggcttccag
    38041 taatagtaag tatgggatat tcagcagagc aaatagctga ggttgctcct ttagtaaagc
    38101 cttatgcaga tgcagttgaa ttatctactc attatgtagg tacagacgtt gcaccaatag
    38161 taaatgcttt aaaagctgca aaagctgttt tagatgtacc agtatttatg aaaatgagtc
    38221 ctcatactga cattcaaact attgcaaaag ctgttgaaga agcaggtgca gatggacttg
    38281 taatgataaa ctcatttgga ccatgtatgg caatagatgt aaatacagga taccctataa
    38341 tgggaagtaa agctggatac ggatggttat caggtgcacc aataagacct ctagcaataa
    38401 gatgtatata tgaagcttct caagttgtaa atataccaat aatcggtgtt ggtggaatca
    38461 cttgtggaaa agacgtggct gaaatgatga tggctggagc aagtgctgtt caagtatgta
    38521 cagaagcaat ccttaaaggg ccttctatct atggaaaaat tgctaaagaa ttaaatgaat
    38581 ttttagatga gaatggatat gctgatgtta atgaaataaa aggattaact cataagaaaa
    38641 tggcagctag agggtttaga actcattcag tagctccagt agtggatgat aacaagtgca
    38701 tcaaatgtaa gcaatgtgta acaagctgtg tatacgaagc tttagaagtt acagataagt
    38761 tgaacataga tgcagacaag tgttttggat gtggattatg tgtaactaga tgtccaaaag
    38821 gagctttaag catctgctac aatcaagtag aagctatgaa tgagtaataa ttatatagaa
    38881 ttttggtaat taacttagag taataggtat taggataata aaatatatca gataaacaaa
    38941 cacacattat gcattaataa tacagtctaa agttaataat tttattatat tgatttaact
    39001 aaatattagt ttagctgaat attaatttaa ttaggtattg gtttaatctt aatatagatt
    39061 tactacgtat aagtgaacta actagattac tttaagttaa ttttttcata taaaataaat
    39121 tgatacatta caagtaaggt ggagtctata tgggaattgt tttaaaaggt gggaaagtag
    39181 taacaagtga aaaaacttac tgtgcagatg taagaataga agatgaaaaa atagtcgata
    39241 taggtcttga tatatcaaaa gaaaatgatg aaatagttga tgttagtgat tcttatgtta
    39301 taccaggagg tatagataca cacacacact ttgacttaga tacaggcgtt actaagacag
    39361 cagataactt tgagacagga acaaaagctg ctatagtagg aggaactact actatattgg
    39421 attttgctac acaagctaaa ggatgttctt tgaaagacgg attagaagaa tggcatgaaa
    39481 aagctaagga taaatcctat tcagattatg gctttcatat ggctataaca gattggaatg
    39541 actcggtttg taatgaaatg gaggatatgg tgaaagaggg agtatcttca tttaaactgt
    39601 atatggcgta taaaggaagc cttcaagttg atgatggtgt aatctttgaa gcattgagaa
    39661 aagcagaaga gataggaggg attattggtt tccattgtga aaatggggac ataatatgtg
    39721 aacttgtgga taaagcaaag tcagaaaata atttatctcc aaaatatcat caattaacta
    39781 gaccagctat aatggaggca gaagctacat caagacttat gaagatagct gaagttgcaa
    39841 actcaaaagt atatgtagtt cacttaagct gtaaagaatc cttagaggag gttttaaaag
    39901 ctaagcaaag aggtgtggat gtaatagttg aaacttgtcc tcaatacctt ctattaaatg
    39961 atgaattata tgatttagat ggatttgaaa gtgctaagta tgtaatgtca ccacctttaa
    40021 gaaataaaga aaataatgaa atattatgga atgctatttt agataatcaa atagacacta
    40081 taggaacaga ccattgttct tttaattata agggacagaa ggaacttggg ataaacgatt
    40141 tcagtaagat accaaatggt tctccaggtg tagaacatag gatgagtctt ttatacacat
    40201 atggagtctg taaaaataaa atatctatca acaagatggt agaagtaaca tcaactaatg
    40261 cagcaaagtt gtttggaatg tatcctaata aaggaactat agaaataggc agtgatgcag
    40321 atatattagt cttaaatcca aacaaaaaat ccaaaataga agcaaaaaaa caattacaaa
    40381 atgtagatta tacaccttat gaagggtatg aagtggattg tcaaatagaa catgtttatt
    40441 taagaggaaa agaagtagtt agagatggag aattaatttg taatactcca agtgggagat
    40501 atataaatag gcgtctaaca aagggggcta gagaatggta gaatttatat taaatggaga
    40561 gaaagttgtt gcaaaagaag gcaaaaaact tttagacttc cttagagaag atatgaatat
    40621 aacttcagtt aaaaatggct gttcagaagg tgcttgtgga acatgtatgg ttataataga
    40681 tggtaaagct actaaagcat gtgtatttaa aactgataaa ttagctggga aaaacataac
    40741 aactatagag ggattatcag agagagaaag agatgttttt gcatattctt ttgctagtca
    40801 aggagctgta caatgtggat tttgtattcc aggtatggta attagttcaa aagcacttat
    40861 agatgttaat aataatccta ctgaagatga tataaagaaa gctttaaaag gtaatatatg
    40921 tagatgtaca gggtatgtaa aaataattaa agctgtcgat ttagcagcaa agatttttag
    40981 agaaaatata gatgtgccaa aagtaaactg taagggtcta gtaggtgaaa atcttcctag
    41041 agttgatgca gttggcaaag cacttggata ttctgaatat gtagatgata tgagaattga
    41101 gggtatgatt tatggttcag cagttagagc taagtatcct agagctttag ttaaaaaaat
    41161 agatatagaa gaagcaaaag cttatccagg agttgttgca gttctaacag ctaaagatat
    41221 tccaggaact ataaaggtag ggcacttaaa gaaggattgg gatactttaa taccagaagg
    41281 tgaaataact agatatttag gagatggaat agttttagta gcagcagaaa ctagagaagc
    41341 gttagaagag gccaaaaagc tagttaagat agattatgag gaattaacac cattaagtac
    41401 tacagcagat gcacttagag aagatgctcc aaagatacat gagacaggga atatacttgt
    41461 taaggaacat ttagtaagag gaaacgctaa agaaaagata gaaaattcaa aatatgttgt
    41521 aactaaaaga tatactacac ctgctacaga acacgcattt ttagagcctg aatgtgcagt
    41581 agctggtcct tatgaagatg atggagtaat aatctattca acagaccaag gggtgtttgc
    41641 cactcaacat gaatgtgcag atatgttagg gttaccatat gagaaggtaa gagttataaa
    41701 caaaatggta ggaggagggt ttggtggaaa agaagacatg agtgttcaac accatgcagc
    41761 cttacttgca taccatacaa agagatttgt aaaagtacag ttaacaagaa aagaaagtat
    41821 tattgttcat ccaaaacgac atgccacaga aatggaattt acgacagcat gtgatgaaaa
    41881 tggatactta acgggtatga aggcaacgat aatatctgac acaggtgcat atgcctctct
    41941 tggaggacca gtgctacaaa gactgtgtac tcatgcagca ggaccataca attatcaaga
    42001 tattgatata acaggaacag cagtatatac taataaccct cctggaggag catttagagg
    42061 atttggagtt acacagagtt gttttgcaac tgaatgtaat ctaaatttac ttgctgaaat
    42121 ggttggaata tctccttggg agataagata taaaaatgca ataagacctg ggcaagtttt
    42181 accaaatggt caatttgcag atgaaggaac agcaatggca gagacactag aagctgtaaa
    42241 agaagagtat gaaaagcatc cacgtgcagg tatagcttgt gctatgaaaa atagtggggt
    42301 tggagttggt atacctgatg ttggaagatg tagattggtg ataaaagatg gcaaagttca
    42361 cataagaaca agtgcttctt gtataggtca agggcttggt actgttatga ctcaagtagt
    42421 ttgtgaaact gctagcctac ttcctgaaaa tatagtgcat gaagttccag atactcattt
    42481 aacaccagac tctggtaata ctacggcttc aagacagaca gtatttacgg gagaagctac
    42541 taaggttgca tcaaataagt taaaagaagc tttagactct ggcaaaactt tacttgattt
    42601 agagggagaa gagttttatg gagaatatga aagtattaca gataaaatgg gttgtgacaa
    42661 agaaaatcca gtaagtcatg ttgcttatgg atatgcaaca caagttgtaa ttctggatga
    42721 aaatggaaaa ctagaaaaag tagtagcagc acatgatgtt ggaagagcta taaatccaat
    42781 cagtttagaa ggtcaaatag aaggtggagt agttatgggt cttggatatg ctctaaccga
    42841 agattaccca gtagttaact ctgttcctac agctaagttt ggtacattag gtttatttaa
    42901 atctacagat ataccagaaa tacaagcttt aatagttgaa aagaacaaag atttattggc
    42961 ttatggggca aaaggtgtag gagaaatttg tacagttcct actgcaccag cagtacaaaa
    43021 tgcctattat gtatttgata aagaatttag aactgagcta ccactacaaa atactccata
    43081 tagtaaaaaa aagtaacaaa aaaaagaaat attaaataaa aaaatagatg aaattgtaaa
    43141 taaaaaaaac ccttttgcat aaggtatatt ttaaatgata gaatatacat atacaggagg
    43201 gtttttcttt tataaaataa gtttaataaa attgagaggt gagcagaatg aattttaata
    43261 atagtctaga attaactcag tctcagaagc taataatgac tacacaactt aagcaatcat
    43321 tatcaatatt aaatatgagt aagttagagt tagaagaaga gataaaaaga gaagcagaga
    43381 ataacccatt agttgaagtc gagaaaagtg gggagataaa ttgggaagag tatataaaag
    43441 acatggatag gtcaagacgt ttagatagaa cagagataag ctataatcct gataatgaag
    43501 ttaatctaga aaatttagtt aaatattcgt caaatttata tgaagattta aaatttcaga
    43561 taagcctgta taaacttaca gacaaagaat tggaagtctg tgagtatata attgatagtt
    43621 tagatgagga tggatattta agaactgagg aaaaagtaat tgttgatacc ttaaagatag
    43681 atgaagaact ttttgaaaaa tgtttaatta gtgttcagca gttggaacct agtggagtag
    43741 gggcaagaag tctttcagaa tgtctgatga tacaaatggc tagtttagga atatataatg
    43801 aaattttaga ggaaatcgtt acaaaagact taaatttaat tgcaaataat aaatataaag
    43861 agataagtaa aaagtacaat atgtcattac aaaaatgtgt tgaactaata aacataatta
    43921 agacattaga ccccaaacca ggaagaactt gttcagtaga gaaaagtgta tacattcaac
    43981 ctgatgtaac agtagaaaag attgatgatg aatttattgt atatttaaat gagaaagatt
    44041 cttaccaaat aagaatcaat agttattata aagacatatt aaaaaattca cagtctgatg
    44101 aaagtgcaaa agaatttata aaagaaagac taaattcagc aacaggactt atgaaaaata
    44161 tagagagtag gaaaactaca gtacttaaga ttgcagaaga gatagtaaaa gctcaagatg
    44221 aatttttgag aaaagggaca aaatatataa aacctttgaa aatgaaagac atagcagaaa
    44281 aattagaatt tcatgaatct actataagta gaggtgtaaa tggtaaatat atgctaacac
    44341 cttttggcgt atatgaattt aggtactttt tcagtagcgc cattgagact gagaataatg
    44401 aaatggcatc tagtacaagc ataaaaaaaa ttataaagga aacaataaaa gacgaaaata
    44461 aaaagaaacc tttaagtgat gaccatatat ctaagttatt aaaagaaaaa ggaatcaatg
    44521 ttgcaagaag gacagttgcc aaatatcgtg aagaattagg aatcccatct tcaagtaaga
    44581 gaaaagaata ctaataagta aaagacaaat atcagtatgg taaggggaaa aggctaatta
    44641 agagatgaat gtagattggg ctaaaaattt tataaagtaa aataatagaa tatggaaaag
    44701 tattaaaatg ctataaggta ttaaaaaact ggggaacatt aaaacattaa gatagcaaag
    44761 aacataaaaa actaaagaag attaaaacat taaagaacat taggctttga ggaatattag
    44821 aactttaaag aatattaaaa tttataaaat ataaaaatac taaaaagaat tgaaaaactg
    44881 gggaacatta aaatattgta aaatgctaaa aaactagaaa acataattaa ataagtgctt
    44941 ataaagaatg attaaattaa ataagtgttt gtaaagaata attagatatt agaaaaagaa
    45001 gaatacctag ataaataaac tattattaaa tttaataatc acaaaaggaa aacacgtagg
    45061 gtataaataa aaatcttaac tagataaaag taa
//
LOCUS       DAMJYN010000030        42710 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.031, whole genome shotgun sequence.
ACCESSION   DAMJYN010000030 DAMJYN010000000
VERSION     DAMJYN010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 42710)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42710)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42710
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.031"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            723..1232
                     /locus_tag="PC466_001688"
     CDS             723..1232
                     /locus_tag="PC466_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2769076.1"
                     /translation="MLSENIKTIRKSKGLSQQELAIKLNVVRQTISKWEQGLSVPDSD
                     MLISISEVLETPVSTLLGETIVESEVDSLKVISEKLEIINLQLAQRKNMRRKMFHWLF
                     ILLCAVIVIVFVVLGGLNSPYLDWNYTDPETAVFGVAFHAFEWLFVRLVPIVLIGAII
                     GIFLTRKKI"
     gene            complement(2143..2943)
                     /locus_tag="PC466_001689"
     CDS             complement(2143..2943)
                     /locus_tag="PC466_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2769077.1"
                     /translation="MRLNKRSEGYINYVKGVKREKRNVLFYQLLILIGFIVIWELLAD
                     LNVINTFLFSKPSDIYNLFIQYAFSGQLFKHIGISVYETVLGLVIGTVLGILVAIALW
                     WSEKLSKILDPFLVVLNALPKTALAPIIIVWVGAGIEGIVVTAVTISVVVTILSAYNY
                     FMNIDEEKIKMLKSFGATKSQILFKLILPANTGNLINLTKINIGMAWVGVIVGEFLVS
                     RYGIGYLIVYGSQVFKLDLVMMGVFVLAICAWAMYAVVNIIEKIYNSR"
     gene            complement(3138..4736)
                     /locus_tag="PC466_001690"
     CDS             complement(3138..4736)
                     /locus_tag="PC466_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDF2769078.1"
                     /translation="MKAAIYSRKSRFTGKGDSIENQIQLCIDYAKSIGVKDFLIYEDE
                     GFSGSNIDRPQFKKMMQDAKDKKFSYLVCYRLDRISRNVSDFSTLIEKLNELNISFIS
                     IKEQFDTSTPMGRAMMFISSVFAQLERETIAERIKDNMYELARSGRWLGGNTPHGFNS
                     EKITFLDENLKERSMYKLQVNDEQMEIVKLIYNKYLELRSLSKLYKYVYNNGIRGPRG
                     GKFDPSSLSRILRNPAYVKANDEILDYLKNSGMDVVGTPDRKCGILTYAKNTSNSIAA
                     IAKHHGVIEPEIWLEVQNQLDKNRDKTPRISTGKTALLSGLIKCGKCGSNMRITYKGK
                     KTDKDLKYYYICGTKKTLGSDSCNCKNLNGPLVESLVIDKIKNCKEESIISAFNSNNI
                     KTDNVFNIFKSETNLLKNQILDKERLIKNLVIELAKNTGSTASDYIVSQIESLNNEIS
                     ILKDKINILESSNINISSDSINIDIIVSNLKRFNDEVDNASLDDKRLLLSTIINSIIW
                     DSSLGNLNIVYMGAEVDNSVSLSN"
     gene            5064..5240
                     /locus_tag="PC466_001691"
     CDS             5064..5240
                     /locus_tag="PC466_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769079.1"
                     /translation="MEINVIEIFPKDKAKLNKIEMDKASWFVNIISKKYPKEALNEAF
                     SILEKELNISKANT"
     gene            5414..6544
                     /locus_tag="PC466_001692"
     CDS             5414..6544
                     /locus_tag="PC466_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003462216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HDF2769080.1"
                     /translation="MNNFEIKTRIKFGEGSLKVLQELKNKNVLIITDPFMVKSKTIDK
                     ITSNLINSTYQVFEEIVPDPPIEVVVAGIEAFKSINPDVIIALGGGSAIDAAKSIMDF
                     SKKILKINEVEFIAIPTTSGTGSEVTSFAVITDSQKKCKYPLVSDDLLPDMAILDPEL
                     VKTVPNFITADTGMDVLTHAIEAYVSTNSNDFSDALAEKSIKLVFKYLIKAYKDGNDI
                     EAREKMHNASCLAGMAFNQASLGINHSIAHVLGGKFHIPHGRTNSILLPHVIEYNSSI
                     VGYTNTTYSDTAKKYAQIAELVGLGSANIRISVRNLVNEIKKLQKEMNMPTKLTQCKL
                     SLEDITNEEREIAKLAIKDTCTLTNPKVPTEDDIINILNNIK"
     gene            6785..7135
                     /locus_tag="PC466_001693"
     CDS             6785..7135
                     /locus_tag="PC466_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003453843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMC domain-containing protein"
                     /protein_id="HDF2769081.1"
                     /translation="MTEESKQRVIQEYVPGKQVTLAHIIANPNEDIYKKLGLVLDKRD
                     AIGILTITPSEASIIAADVATKASNVSLGFIDRFSGSVVISGDVSSVESALNDVLEVL
                     GNMLNFSSTKITRT"
     gene            7143..7592
                     /locus_tag="PC466_001694"
     CDS             7143..7592
                     /locus_tag="PC466_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EutP/PduV family microcompartment system
                     protein"
                     /protein_id="HDF2769082.1"
                     /translation="MKNIIFMGKTGSGKTTLCQKLDQLELKYKKTQSVELYNNAIDTP
                     GEYMENRNLYNALITTSADAKIIAIVYDATQEENYIAPGFASMFCKDVIGIITKINKA
                     TENEVNIAYERLSLAGASQIFKIDTVDDIGLEKLFKYLEKSKNIDEV"
     gene            7694..8269
                     /locus_tag="PC466_001695"
     CDS             7694..8269
                     /locus_tag="PC466_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HDF2769083.1"
                     /translation="MGKKILLVDDEPLLRMDTKDILESHGYEIIGEASDGFEAVEMCK
                     KHKPDLVIMDIEMPILDGIKAGKIICKENLAGGVLLLTSFEDKEYVEKAKSIGAYGYL
                     VKTASEKSLIPTIEMCLNKVNEFEKMKKDLEKVNSKLNERKLVERAKGILIREFKISE
                     DEAYTRIRKLSMDKRTTMMEIAKMIIIGYDD"
     gene            8262..9671
                     /locus_tag="PC466_001696"
     CDS             8262..9671
                     /locus_tag="PC466_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase N-terminal domain-containing
                     protein"
                     /protein_id="HDF2769084.1"
                     /translation="MTNTIKKISTAQTYLNNNEIEKIIEVSKSLDLMASFYEADVFID
                     VLSKFDDEAIVVAHGRPKEKSMYCENVIGKKALIENEPGVIKCLKTGERVRDIKALTQ
                     EYKLVKQNIQPITLDDKVLAVLIVEKDISSEVKNEFNASEDEENKNLHQFIKLIGNND
                     FLVDNLNSAILIFDKNGKLKIKNRIATEIYKNLGFGYDIQDMHYNDLDIETNTFENIL
                     MDENYDETNEVSIGNMFFKIKTIYIKDDEFKVCKIVQDISDLKRKEEELVLKTVAIRE
                     AHHRVKNNLHTVISIIKKQSRLSQNDEVKQCLDNIINRVFAILSTHYLLSKEVDNNIS
                     IREGINLLVSNIQGGYLFSKDIDIRITGEDFKISGEKATAILLVINEILQNCYDHAFS
                     DREHGTIQILINKDNDYRNIAIIDDGIGFDSNNINKNSLGTYIIDSYITQMLKGNIER
                     KSNENGTEVLITIPTQINI"
     gene            9855..11288
                     /gene="eutA"
                     /locus_tag="PC466_001697"
     CDS             9855..11288
                     /gene="eutA"
                     /locus_tag="PC466_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004458698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase reactivating factor
                     EutA"
                     /protein_id="HDF2769085.1"
                     /translation="MREELLSVGIDIGTSTTQLIFSKLIVENTESNFSVPRISIVDKE
                     IIYKSKVYFTPLISNNEINGQQIKDIVENEYKKANISKEDIHTGAVIITGETARKENA
                     NDVLHTLSGFAGDFVVATAGPDLESIISGKGAGAHIYSKEHSTTIVNIDIGGGTSNIA
                     SFKRGEVTDTGCLDIGGRLVKIDKISKKITYISPKIDKIIKDNNLNLQVGTMATVENT
                     KPIVDIMVDLLMESIGLKKQTPLFDFIITNKSISIDENIKNVSFSGGVADYIYYDGEI
                     KDYFEYGDLGILLGQTIKNCEYLKKVNVVKSMETIRATVVGAGSHTTEVSGSTITYTS
                     EKFPLKNLPVLKLSVDEETGTSKQISEAIKNKLNWFKLENDLQKVAIAMIGKKNPTFL
                     DIQEYAKGFVDGMQQIIENDLPFIVIVENDMAKVLGQAIYALLNYEKEIVCIDSVKVE
                     NGDYIDIGKPIVEGKVLPVVIKTLVFN"
     gene            11306..12670
                     /locus_tag="PC466_001698"
     CDS             11306..12670
                     /locus_tag="PC466_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003454054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase subunit EutB"
                     /protein_id="HDF2769086.1"
                     /translation="MILNTKLFGRTYQFKGLYDVMAKANEEKSGDKLAGLAAESAEER
                     IAAKVVLSHIKLEDIRNNPAVAYEEDEVTRIIQDAVNEKVYEEIKNWTVSELREWLLD
                     SNTTSLDIRRISRGLTSEMIAAVAKLMSNMDLVYAAKKIKVTAHCNTTIGEQGTLSAR
                     LQPNHPTDDPDGILASLLEGLTFGIGDAVLGLNPVDDSVESVTKVLKRFEEVKQKYQI
                     PTQTCVLAHVTTQMEAIRNGAPADLIFQSIAGSEKGNEAFGFNGDTIEEARQLALKHG
                     TATGPNVMYFETGQGSELSSEAHHGIDQVTMEARCYGFAKKYEPFLVNTVVGFIGPEY
                     LYDAREVVRAGLEDHFMGKLHGLPMGVDVCYTNHMKADQNDMENLAILLTTAGCTYFM
                     GIPHGDDVMLNYQTTGYHETASLREMFGLTAIKEFDAWMEKMGFYKDGKLTELAGDAS
                     VLLG"
     gene            12683..13564
                     /gene="eutC"
                     /locus_tag="PC466_001699"
     CDS             12683..13564
                     /gene="eutC"
                     /locus_tag="PC466_001699"
                     /EC_number="4.3.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014952556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase subunit EutC"
                     /protein_id="HDF2769087.1"
                     /translation="MNEKDLKALVEQLVGQMVGELDTNVVSETVKKTTEVVVDNNAFI
                     DDITEVDIRKQLLVKNPKDAEAYLDMKAKTPARLGIGRAGTRYKTETVLRFRADHAAA
                     QDAVFSYVDEEFIKENNMFAVETLCKDKDEYLTRPDLGRKFSQETINNIKSKFGTNQK
                     VLILVGDGLSSAAIEANLKDCVPAIKQGLKMYGIDSSEILFVKHCRVGAMDHLGEELG
                     CEVICMLVGERPGLVTAESMSAYIAYKPYIGMAEAKRTVISNIHKGGTTAVEAGAHIA
                     ELIKTMLDKKASGIDLK"
     gene            13584..14237
                     /gene="eutL"
                     /locus_tag="PC466_001700"
     CDS             13584..14237
                     /gene="eutL"
                     /locus_tag="PC466_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003761789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutL"
                     /protein_id="HDF2769088.1"
                     /translation="MKNDVIRPNILGIKIISNISPEMAQKLELKSHHKSLGLITADCD
                     DVTYTALDEATKASEVDVVYAKSMYAGAANASTKLAGEVLGIIAGPSPAEVRSGLNAV
                     VDFLEYGATFISANDDDSIAYYAHCVSRTGTYLSEIAGIREGEALAYLVAPPLEAMYA
                     LDAAMKAADVKMCELFAPPTETNFGGALLTGSQSACKAACDAFAEAVKSVADNPTGF"
     gene            14248..14949
                     /locus_tag="PC466_001701"
     CDS             14248..14949
                     /locus_tag="PC466_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMC domain-containing protein"
                     /protein_id="HDF2769089.1"
                     /translation="MDAIGLIEVIGYVAAIEASDACLKSANVNIVRIDKVGAGIVTLT
                     ICGDVGAVKAALEAGEIAASRVGTLRTSHIIPRIHNEVTNALFKTKEPKVCEVSEDKE
                     KNFEITLEITDNVSKNLSEKENVILDVNENSGDTENLYSDIDKTNKKIETVDDSLTEA
                     NEEKIENTNDKEVLEQVKIENSDFDRDDLSKNSVKKLKAMAKKLDSSITYKDLNVLKK
                     EELINLVKKLSRRDR"
     gene            14952..16421
                     /locus_tag="PC466_001702"
     CDS             14952..16421
                     /locus_tag="PC466_001702"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetaldehyde dehydrogenase (acetylating)"
                     /protein_id="HDF2769090.1"
                     /translation="MTLLDKDLVSIQEVRTLVRRSKVAQEKLSKMSQEQIDKIVKAVV
                     DAAFNNATKLAKMANEETGFGKWEDKVIKNTFASMGVYETLKNTKTIGIIGEDKEANT
                     IDIATPVGVVAGLIPSTNPTSTVIYKTIISLKAGNTIVFSPHPNAKNCILETVNIISE
                     AAIKAGAPEDSILCITNPSIVGTNELMKHKDTNLILATGGEAMVRAAYSSGTPAIGVG
                     PGNGPAFIDKSANVKLAIKRIIDSKTFDNGVICASEQSIVIEKSMEETVLKELKNQGA
                     YVLNEEESERLAKFILRANGTMNPQIVGKSVEVIANLADLTNIPKNTKVLVARENKVG
                     HNVAYSREKLTPILAFYVEENVEAIMNRCREILLNEGAGHTFSMHVNDEELVKRFALN
                     MPVSRILVNTPSALGGIGASTNLVPALTLGCGAIGGSSTSNNIGPLDLINVKRVAYGI
                     KEIEELGRDKSQVEKSMFDSMDKEELINLLVQKLVKELA"
     gene            16517..16804
                     /gene="eutM"
                     /locus_tag="PC466_001703"
     CDS             16517..16804
                     /gene="eutM"
                     /locus_tag="PC466_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutM"
                     /protein_id="HDF2769091.1"
                     /translation="MASANALGMIETKGLVGAIEAADAMVKAANVQLVGKEQVGGGLV
                     TVMVRGDVGAVKAATDAGAAAAERVGELISVHVIPRPHFEVDAILPKVSAE"
     gene            16931..17692
                     /locus_tag="PC466_001704"
     CDS             16931..17692
                     /locus_tag="PC466_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin adenosyltransferase"
                     /protein_id="HDF2769092.1"
                     /translation="MGVLTENEVKRKIGKNKNNITEFYIEKGQIITPSAKSYLAERSI
                     ELKYVDKLSDVNNEPKEVVKEVVKEKKYKYTTVFGAKLDEKPEHMTQLNGNLLVFKDH
                     KRIILRGKIDSLESEILKVQILCQKLDMPKLVKELQEVLDFVRNIMRCEVLDEKLEDF
                     KLLGLTPQELREQSHYPKKYFGIGHEFPSYEMGEVVVAINSIRSNTREVELAAYEAFK
                     GEYGNVHREDLIKALNRLSSVFWIMIYKVRTNKYK"
     gene            17705..18334
                     /locus_tag="PC466_001705"
     CDS             17705..18334
                     /locus_tag="PC466_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate propanoyltransferase"
                     /protein_id="HDF2769093.1"
                     /translation="MENLLNEIVEEVITRVKKEAFIEVEASGRHVHLSREDVDKLFGE
                     GYTLTKLKDLSQPGQYACKERVTITGPKGSIKNVVVLGPCRNETQVEISLTDGSTLGL
                     KAPIKQSGDLEGTLSIKISTQYGEVELDKGLMVAKRHIHMTPKDAEKFNVCDKEIVEA
                     KVMGQRPLTFDDVVIRVSDSFKTYMHIDYDEANACGYSKGTVAKIIKKA"
     gene            18376..19101
                     /locus_tag="PC466_001706"
     CDS             18376..19101
                     /locus_tag="PC466_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02536 family ethanolamine utilization
                     protein"
                     /protein_id="HDF2769094.1"
                     /translation="MNYDNLVDLITEEIYKKINSNEIKISNKPKAVIVFEQDNNKFNL
                     LKDEFEILEFDKSIRECEIVIVSRLCMRGLSNIALGNSTSDEERFILKMIMKGKKVYV
                     LDEGIEYKKYKDTAPKALYKKFMSFEDEICKFGVEIIKDLNVITKNKLNIKKELESTR
                     GSKKEDTKVLDKDVLNLTSVESVKIDNEFSLDLRNKKLISEADLRKPTINGVKNILVN
                     KKSIITPLAVDFMRIHHLKLKKL"
     gene            19114..19386
                     /locus_tag="PC466_001707"
     CDS             19114..19386
                     /locus_tag="PC466_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EutN/CcmL family microcompartment protein"
                     /protein_id="HDF2769095.1"
                     /translation="MDIGKVVGNVWATRKDEKLCGQKLLVVKILKTKDTYKEGFMVAA
                     DNAGAGNGDLVLISKGSSARESIEKSHVPVDATIVGVVDSFEVFDE"
     gene            19379..19930
                     /locus_tag="PC466_001708"
     CDS             19379..19930
                     /locus_tag="PC466_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMC domain-containing protein"
                     /protein_id="HDF2769096.1"
                     /translation="MNKSIGAIEFKSIAKGIEVSNEMIKKSSVDVLYLKSICPGKFLI
                     IVGGETSYINECVDYGIKLGEGYIVDNFVINAISQEILDGFKNKYQKLDSIVSIGVVE
                     SSKVCAGIKMLDKTLKSGDLVLVKLQLSFAIGGKLVYVVAGDLSSLEYALKESENVVR
                     EKEVIYKTVIPSVDSQIIKSLIK"
     gene            19942..21033
                     /gene="eutH"
                     /locus_tag="PC466_001709"
     CDS             19942..21033
                     /gene="eutH"
                     /locus_tag="PC466_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization protein EutH"
                     /protein_id="HDF2769097.1"
                     /translation="MSINEIIIYVMVVFMVLGAIDKCIGNKFGLGEQFEEGIMAMGSL
                     AVAMVGVICLAPVLADVLRPIVVPVFNILGADPAMFAGSLLANDMGGAPLALELAKDP
                     NSGLFGGLIVGAMMGPTIVFIIPVALGIIEKEDQKFLATGILAGIITIPIGAFVGGLV
                     AGFEVMMVLRNLVPIIIFAVVIALGLLKFENAMIKGFTYFGKGVVIVITLGLAAAIVE
                     ALTGIVVIPGMKPISEGIEIVGDIAIVLAGAFPLVFVITKVFNKPLMALGKVLGMNDV
                     SAAGLVASLANCIPMFGMMKDMDNRGKIINVAFSVSAAFVFGDHLGFTAGFNSNMITP
                     MIVAKLVGGITAVLLAMVIANKTLRKENV"
     gene            21035..21508
                     /locus_tag="PC466_001710"
     CDS             21035..21508
                     /locus_tag="PC466_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF861 domain-containing protein"
                     /protein_id="HDF2769098.1"
                     /translation="MDISNIDKNLIETLVRQIIEEKISGTKDTVDFVRNKDISGITSI
                     KLPTVKVSESDRLDTGNPSDVVYTKDLFTLEESPRLGCGMMEMKETTFDWTLNYDEID
                     YVIDGTLDIIIDGRKVSASSGELIFIPKGSKIQFSVPDYARFIYVTYPADWASQN"
     gene            complement(21628..21729)
                     /locus_tag="PC466_001711"
                     /pseudo
     CDS             complement(21628..21729)
                     /locus_tag="PC466_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433047.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
     gene            22024..22545
                     /locus_tag="PC466_001712"
     CDS             22024..22545
                     /locus_tag="PC466_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF2769099.1"
                     /translation="MEEIVKKEQASMNDIFLYLKAKSNSLYKFVILYNEFINKPKDYG
                     TGELINMVEVHMLTAIEENPGISPTQLAKIWNRTKGAISQTISKLEKKGYITKEKKEG
                     NAKTILLYPTTSGVELSKAHKLYDTIDVTRTFEYLIKECTLEEIDSFYKVIDLFINLL
                     EESPQENNDSEKV"
     gene            22924..24099
                     /locus_tag="PC466_001713"
     CDS             22924..24099
                     /locus_tag="PC466_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2769100.1"
                     /translation="MNLKQLSEKYEEYVIQMRREFHKYPELSFKEIRTTQRIREELQK
                     IGVPFVSIEPNIVIATIQGKNEGKTIAIRGDIDALPMQEDSDVEYKSEYDGIMHSCGH
                     DAHGAMLLGLAHMLNDIRKDLKGRVLLVFQAAEEVGGGHKEIIQYFKENGGPDRLIAT
                     HVWSDIEAGKISVEPGPRMAGGSGWRIDITGRGGHGSRPDQSIDPIKPACDIVLKVSS
                     IPVNHISVLEQCVVHACAIHGGTTIGNVIPNNAEVIGGYRYFTEESGKKVFDIIKQMS
                     NGVGQAYGVDVKVTHTGGIGPVINDEEAVKMAKEIVSNIDGLELDSYEPICASDCYGE
                     ILKEYSGFYCYLGVGNKEKGIIYAQHHPKYNIDEDTLKLGCEFMAKYAVEFLNKNNN"
     gene            24134..25672
                     /locus_tag="PC466_001714"
     CDS             24134..25672
                     /locus_tag="PC466_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbgT family transporter"
                     /protein_id="HDF2769101.1"
                     /translation="MQGALKENKKKSGGGFLGWIERVGNKMPHPLALFTYITLIVVAL
                     SAIASFLGFSATSPATGKLIKVMNLISAKGLVLFMQEFVKNFQNFPVLGVVLVMAVAT
                     GVCEKTGFFSTAIKMSLSKVKGNAVVFIIAFIGVFANQAGDAAFVLVPTLAGAIFYGL
                     NRNPLAGIFCGFASVGGGFATAVIPGGWDVTLTPITVSAAQTIQPAFDMTLLASYYAL
                     FVSAFIVATVSTIVTVKFIEPKLGKYTGKPEGIDDNQGFEVTKEQAKAAKLAGFTVLA
                     YVALLIALCIPANSFLRSPEGSLIFGAPLMSCLQFFIVILFFLPGIVYGMRVGKIKTV
                     KDLNDILCQSMAAMAPFIVLAIVIGQFLTLFSVSNLAQVLAIKGGALLNSLPLPPQVI
                     ILLFLVLVAFINIFVISGSTKWMIFGPVFVPMLMQLNIHPAFTQFVYRLGDSVTNHLS
                     PLNAFFIILLATVQKYDKNAGMGTIFSAMIPYTIGYFVVLAVLVVVWMTIGIPVGIGG
                     QVWL"
     gene            25704..26906
                     /locus_tag="PC466_001715"
     CDS             25704..26906
                     /locus_tag="PC466_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HDF2769102.1"
                     /translation="METTEIRYNFDEVIDRSGTNCLKYDLKSQFMPESPEDALPLWVA
                     DMDFACAPEIINAMHERIDRKIFGYSSQQTDDYYEAVCGWFKRRFDWKIEKENIFFSP
                     GVVPALGFFIQILTQKGDGIIIEKPVYYPFEDKITNNERKVVNSPLKFEDGHYSMDYD
                     GFEELAKDENNKVFILCSPHNPVGRVWKKEELRKIVDICKKYDLWIISDEIHCDIIRK
                     SEKHIPLEVACPDYKDRIITCTAPSKSFNLAGMQLSNIVINNKELQEKWMLETDSKLA
                     IFLPNPFAIVATKVAYNDCEDWMNQVNEYIDGNIKYVEDFVNEYMPKVKIIKSQGTYL
                     IWLDFRGYGLDAKQLEYVMLNKAKVLLDEGYIFGEEGAGFERINVASPRTIIEECMNR
                     IKCAFEGL"
     gene            complement(27085..27684)
                     /locus_tag="PC466_001716"
     CDS             complement(27085..27684)
                     /locus_tag="PC466_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF2769103.1"
                     /translation="MNDNIVEVKNINMNFYTKEGELEVLKDVNFNLKEGEILTLLGPS
                     GSGKSTILNILTNLLKPTSGDIKITGNIGYMFQKDNLLEWRNIMDNITIGLEIQGKKD
                     KKSLDRVESLLKTYGLWDFRSMYPKELSGGMRQRVALIRTLSVNPDILLLDEPFSALD
                     YQTRLLVCDDVYSIIKNENKSTILVTHDIGEARCIKVQL"
     gene            27853..29211
                     /locus_tag="PC466_001717"
     CDS             27853..29211
                     /locus_tag="PC466_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769104.1"
                     /translation="MSNIITNLIESVFTNPITILFLLAITVYSVFKIIENNRVYSFVS
                     SKLDEINRDYKTSEFYKKVRDDYYTYSKENPYADVNITSFIEEVVSDLKHNNLPLLEK
                     IRSIKNSSSISILLGVLGTFVGLSTMLLCVDTKDIINSLPSTISSMQTAFTTSIFGVV
                     FSLIIGYFTKIKDCEHVLIQIMLKSENLLTSEITHFKSERMDLKVEEVKNTIKQISKS
                     IEAIEKFDKISKDLNDFNDEFISGIEALKSLLEGSQSSIKTFDQSVRKLDKQFNILNI
                     KFVKLFDKYDNQDNINKEILFDIKESSKNIYNATESQFKIRDYIKNINAGFALYERSA
                     QDLLTKLMTHENKISQNQKILLDEKFTLDDSIKNLSSIIENFSNDLQVKLDMMFENSL
                     DIQDKLDVMFNNSFMNDEVPLDSEELFKDDVNNVFNPFSEEIYEIEDKEIKVIGEDEL
                     NE"
     gene            29204..29836
                     /locus_tag="PC466_001718"
     CDS             29204..29836
                     /locus_tag="PC466_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HDF2769105.1"
                     /translation="MNNKYRRTVNREFEKSSFWPTFTDLLSTVLMVVILILFSSESIS
                     GSVEQDLAKNVNASVEETFKKSKIPVKVDKSNGQVTFGEKTMFDVDSDVLKPEAKEML
                     KMFVPKYIETIYKDYGDYISKIVIEGHTDDVGSYIYNLDLSQRRAYSVAKFIVGDEIG
                     DYKYKDKVTKHIIAIGRSKAELIKNGDNSVNRDASRRVELKYEININQNK"
     gene            30165..31322
                     /locus_tag="PC466_001719"
     CDS             30165..31322
                     /locus_tag="PC466_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF2769106.1"
                     /translation="MIEISIKNKKNSKIKTLILLLIVSISIYLTGCTTSDNGNNQSNN
                     NDSLSSSISSDKNVKIHFIDTGNSDAILIQDGKTFTLIDGGDNDDEGLMVDYLNNQGV
                     KDIKYLIATHSHADHLGGLDSVVKNFNIENVFVSNGSAETKSYRDFINALANKGLSPS
                     VPLENNKFYLEDSYFEVLNTNGGDTTNEQSLVLVYTNGNDKVLFTGDAEEGTEKEILP
                     KLEKVDLLKVAHHGSRSSSSQEFLDKVNPEYAVLLVGKGNSYGHPHQETMNKLKKMGV
                     KVHRSDECSDIIFESTGDGVFTSCKDGSYNKGVREDGNSGKSNSNTSKNDSFKNKQNT
                     FNSEEIVYFTPKGKSYHSIKNCSGLSRSKKILSGTIEESKKNDPCDICYGK"
     gene            complement(31470..32105)
                     /gene="lexA"
                     /locus_tag="PC466_001720"
     CDS             complement(31470..32105)
                     /gene="lexA"
                     /locus_tag="PC466_001720"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HDF2769107.1"
                     /translation="MYLDLTEKQVLILEFIKSQITLKGYPPAVREICTAVGLRSTSTV
                     HSHLNKLEKLGYIRKDPTKPRAIEVLERSKVNDVSGANQEIIELPLVGQITAGEPILA
                     QQNIEEYIPFPASLVKGSNNFVLRVKGESMINAGILDEDYVVVDKKNTALNSQIVVAL
                     INGESATVKRFFKEGNLIRLQPENDFMEPIMLNDSEVEIVGIVTGVFRVIK"
     gene            complement(32209..33336)
                     /locus_tag="PC466_001721"
     CDS             complement(32209..33336)
                     /locus_tag="PC466_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDF2769108.1"
                     /translation="MNNDKKIIKVHNKSDKPDNIVIKENELIEKCLLLENKLPVFMKD
                     YFIYLKGSVAVSTRLAYLEDINFFCSYLIETKELTNADCVKDITEDDFNTIKSRDINL
                     FLGDYCSRYYKNTEKNTLIFENNNRALARKKSSISTLFKFLYRNSQIDNNITDGFNPI
                     KLPKPQPDAIKRLEIDEVAKMLESVETGEGLTEKEKVYWRKTKLRDKAILALFVTYGL
                     RLNELRELNISSFNFSRGEFKIYRKRGKEVLMPINHTCEHVIKDYLQNERTRDELLND
                     EEKDALFLSLQNKRITAKAIRTLVKKYTSIPLDTTRDNGYSPHKLRATAATSLIQTGF
                     SIYDVQNLLDHDNVTTTQLYAAHKKNVKRDIVKNFEWIEDD"
     gene            complement(33658..34503)
                     /locus_tag="PC466_001722"
     CDS             complement(33658..34503)
                     /locus_tag="PC466_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769109.1"
                     /translation="MIYIIEILKISVINIFCFIGIFIVFGLIFSITENLNNKFIFSSF
                     GKTGIIVTGAIGTFVHELSHLIMCLIFMHKINSVKFFRPIESKNDGILGYVSHSYKKD
                     NLYQSIGNFFIGIAPIIGGTIMIILIFKILLPDSYMKVTQNIDLKLYVSMINNLNING
                     FIHIILGDISNFIRIMLLTPSVYSLKYFIFMFLMYSISTHMSLSSADLKNSLNGLSFI
                     VIVIFVISSITYLFGFDNLNISSLIVKYNIFISFFMAIGFIFSIVTLIISYILSLVSP
                     FKNFS"
     gene            complement(34533..34904)
                     /locus_tag="PC466_001723"
     CDS             complement(34533..34904)
                     /locus_tag="PC466_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HDF2769110.1"
                     /translation="MKLKLLVEEYAVCRLNNDSKIPTWIDTEKFYSITRTDDELSVVC
                     LNNNIPSDVKSEKEWRILKILGPLDFSLVGILSKLSSLLADNKISIFAISTYDTDYIL
                     VKEKDIEDACKILSCNGYEVE"
     gene            complement(35057..35317)
                     /locus_tag="PC466_001724"
     CDS             complement(35057..35317)
                     /locus_tag="PC466_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003866776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein S"
                     /protein_id="HDF2769111.1"
                     /translation="MEVLKVSSKSNPNSVAGALAGVLRERGVAEIQAIGAGALNQAIK
                     SIAIARGFVAPSGMDLVCIPAFTDIEIEGDKKTAIKLIIEPR"
     gene            complement(35506..36450)
                     /locus_tag="PC466_001725"
     CDS             complement(35506..36450)
                     /locus_tag="PC466_001725"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit alpha"
                     /protein_id="HDF2769112.1"
                     /translation="MIENNSEKIKVLENDIKQLITISKANNIDLSDKINSLNEKLEKL
                     KEDAFSHLSAYEKVTLSRDIKRPTTLEYIEHICSNFLELHGDRLFKDDPSMVGGIGQI
                     GKFNVTIVGHQKGRDTKENIKRNFGMPHPEGYRKALRLMKQAEKFNRPIITFIDTSGA
                     FCGLEAEERGQGEAIARNLLEMSKLSVPVITFVIGEGGSGGALGIGVGNDVCMLEHSV
                     YSVISPEGLSSILFKDSSKAKEACDVMKLTSNDLYDLKIIDKIIKEPLGGAQKDVEAV
                     SKEIKAYILERLNHYKDMDKEEIIAQRYKKFRNIGKCL"
     gene            complement(36471..37325)
                     /locus_tag="PC466_001726"
     CDS             complement(36471..37325)
                     /locus_tag="PC466_001726"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HDF2769113.1"
                     /translation="MIKKFLSSKESKYVTISLDDNFKKNSVDDKFWTYCKGCDSHVFR
                     KDIEENSFVCPKCSRHYGLRARKRINLLIDKGTFMEFNSDVEFQNPLNFPKYKEKVDS
                     YKEKTKESEAVVTGYGRINGIKTVICVMNPDFMMGSMGSIVGEKITYSIEYAAENNLP
                     IIICSASGGARMQEGMVSLMQMAKTSQALSKLEEKSLPYISVLTDPTTGGVTASFAML
                     GDIIISEPNTLIGFAGPRVIEQTINQKLPEGFQTSEFLLEKGFIDMIVDRRKMKELLY
                     QILAMHKK"
     gene            complement(37340..38701)
                     /gene="accC"
                     /locus_tag="PC466_001727"
     CDS             complement(37340..38701)
                     /gene="accC"
                     /locus_tag="PC466_001727"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HDF2769114.1"
                     /translation="MIKKILVANRGDIAVRIIRTCKELGIKTVAIYSEIDKDCFHRYI
                     ADESICIGPNNISKSYNNIENIIYLALKLKCDAIHPGFGFLSENPEFAKQCEDNNIIF
                     IGPTREQMILMGDKSRARETMMELNIPVVPGSESVLKTKEEALEVAREIGYPVMIKAS
                     SGGGGKGMRIVRKEEELFSNFDMASSEALAAFSNSDLYMEKFIENPRHIEVQVFGDKH
                     SNAIHLGDRDCSMQRRNQKVIEESLSPYLSDEERQKLHKIAVDIVKGVGYIGAGTIEF
                     IVDKDKNFYFIEMNTRIQVEHPVTEMVTNLDLIKLQISIANGDKIPFKQEDITFRGHA
                     IECRINAEDSSKNFAPSPGKIESLNLPGGFGVRFDTFVYAGYTIPPLYDSMIGKLICW
                     AETREECISRIYRALDEIIVEGINTNVEFQKALVTSEEFREDTHHTKFIEDVFMKKEF
                     ATL"
     gene            complement(38717..39169)
                     /gene="accB"
                     /locus_tag="PC466_001728"
     CDS             complement(38717..39169)
                     /gene="accB"
                     /locus_tag="PC466_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HDF2769115.1"
                     /translation="MNINEIKELLKAIDSTNLEYVKLESSDLRLEVSKKAQSTSSPVL
                     SVQQESVVDLSLEKPVVNDTPVTSNENLSVVVAPLMGTFYDSPSPDADSFVKVGDVVE
                     EGDTLCILEAMKLMNEITSEIKGEIIEVLVSNEELVEYNQPLFKIKPL"
     gene            complement(39439..39885)
                     /locus_tag="PC466_001729"
     CDS             complement(39439..39885)
                     /locus_tag="PC466_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769116.1"
                     /translation="MESKFFNWYTQSLGGTFGIISCICAYLNGYMFVYTNSASKYFES
                     IGFLGIISSYTLLPLCMLTLIFGVIYSYTPETSDKSIFNIPFFTLNKRLILITVVFGF
                     IGARVYFIIPAILITFNLYSNVLIAKLKYILCKNKENDTNLKESEV"
     gene            40160..40438
                     /locus_tag="PC466_001730"
     CDS             40160..40438
                     /locus_tag="PC466_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769117.1"
                     /translation="MVDTLEFGLKILFFILSIIWMGKIMILRTDKQIVINPLLIGISA
                     VLVMLHTSQSNIEFFGLDVQYIRIVLYIIYSLIILIGIWATNRRNGIF"
     gene            complement(40567..41313)
                     /locus_tag="PC466_001731"
     CDS             complement(40567..41313)
                     /locus_tag="PC466_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769118.1"
                     /translation="MWEGTMNLANLIPFIISAAALSPINSNDKVLSENQLKDIFPDAN
                     LRAVVKRYINPDEMTISNIKALDGEFYATGESISNLKGISYLENVDNFIFWNNNIKEV
                     PKEALSLKDMDSINLANNYLIDDDVVNSLSHNGVDVNCDLNFIDTKDNQYKLDSKYHN
                     VDIAKGESIDLRKIITKKIDSYYKYWEVTDNLPKDLDFIVSVSDKSVLSCEDMIIKGN
                     KTGQAVVKVILSDKNDLNTSQEVLITVNVK"
     gene            complement(41442..42086)
                     /gene="trmB"
                     /locus_tag="PC466_001732"
     CDS             complement(41442..42086)
                     /gene="trmB"
                     /locus_tag="PC466_001732"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HDF2769119.1"
                     /translation="MRRRRKKGADEKLLSYTKYVLRDDIDKLKGKWNLKFRNDNPIHV
                     EFGTGKGKFITTLAKQNPDINYIAMELKEEVLLKAVEKADASNLNNILFLWGDVSNIL
                     DYFEAKELSRIYINFCDPWPKNRWSKRRLTHSGFLEMYNRVLEDDGEIHFKTDNEKLF
                     EFSLNEIAANNWLLKNISLDLGNSEYENNVTTEYEDKFMSQGMRIFRCEAKKRN"
     gene            complement(42224..42544)
                     /locus_tag="PC466_001733"
     CDS             complement(42224..42544)
                     /locus_tag="PC466_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein HesB"
                     /protein_id="HDF2769120.1"
                     /translation="MKITLPETAIDTLKSILKDNQDKPNNIRVYFAGVGCGGPSFGLA
                     LDEKKEDDLTYEVGELQFVMSSDEYSQYGDIIIEDTGFGFRVIPENMKDQGGGGCSGC
                     SGCH"
BASE COUNT        16193 a         5633 c         6621 g        14263 t
ORIGIN      
        1 tttttagtct aaattatttc attttaaatt aaagttacaa ggaatctaaa attatatata
       61 tctttcttcg taatatgaat gttacaatat aaaaaactgt ctcaataaaa tagagacagt
      121 tttacagtca aagtttataa tacaagttca tatttttctt taaattcttt tacagcttcg
      181 ggccatgcct tttgttctgt aatacctttt tctttagcta ttttaattgc aatctctctt
      241 atcattgcag cgccttctaa tattcccatt tttaatctcc cttcaaatat ctttttgtat
      301 agaatataaa tagtgctaag atttattaca tgctgcatat acaatatcta tacaacacat
      361 aacttgtaaa ttccttttat tttcatacgt ctttaaccga catataatta tattcaataa
      421 gttttaaaat tatgaactca attataatta tttttatttt tttagaatct aaacactaaa
      481 aattgtaggt aaatttgtct tatgccttta taaatatttc tacagtttta attactggac
      541 atatctattt ttattataaa aagcgcttaa aaatcgagaa tatccgcgta aaagctgtat
      601 ataagcaaaa cgattaaagg aaaaagaaga aatttacttg aatgttaaaa tgcgttgctt
      661 gaagcaacgg gcagttttgc ctataatatc ggtaacaact gaaagaaagg tggttagccc
      721 taatgttaag cgaaaacatt aaaacaatca ggaagtcaaa aggactttca caacaagaac
      781 ttgctatcaa actgaatgta gtgcgacaaa caatatctaa atgggaacaa ggactgtcgg
      841 ttcccgattc tgatatgttg atttccatat cagaggtgct tgaaacgcct gtaagcactt
      901 tacttggaga aactattgtt gagtcggaag ttgatagctt aaaagtgatt tctgaaaaat
      961 tagagattat aaacttgcaa cttgcacaaa gaaaaaacat gagaagaaaa atgtttcatt
     1021 ggttatttat tttattatgt gcagtcatag taatagtttt tgtggtctta gggggactaa
     1081 atagtcctta cttggattgg aattataccg accctgaaac cgctgttttt ggagtagctt
     1141 ttcatgcttt tgagtggcta tttgtcagat tagtaccgat tgtccttata ggagcaatta
     1201 ttggaatctt tttgacacgt aagaaaatat gaagtaactc tgctttttat aatatagcaa
     1261 gcgttcctta aaagtgtcat tctacatggc aatcgaggac aactatgtaa ggaagaacct
     1321 ttttgatttc caactaagcg aagttattga ggacgccagt aggcccaaaa ccgcattaag
     1381 taaagtacag gaagcaagac tgctggactt atactctcat gcgtcagatg cagaaaatgc
     1441 gaggtctgta gcatgattta caacgatttg tacaacgact acgagtagaa atatatggag
     1501 ataagtatta tctacgaaat cagaaaagaa atgacttgat aatttactca tgttataatt
     1561 attgatgtga aattaataaa tcgaaattcc ttttttagat ttaacaatac tgagtaagga
     1621 aaaagtgaat gacttttgca aggaggtgtt aatatcaggc aaataaagtc ttttgttttt
     1681 ccagttatat ccttaatatt cttagatcaa attagcaaag ttcttatagg attattctta
     1741 atggactttg aaattgatat aattgggaaa tttttaagat tcaatcctgt tcaaaataca
     1801 aaattaagtc tctgctatct aacaaacgga gcacaaaaat gaaaattaaa tattaaatat
     1861 aaagcacagt taattttgat taaaaagttg actgtctttt cttttttata aatttaagca
     1921 tgggtaataa agaaatgact gcatttaagc attatgtata taattggagg caataaaaag
     1981 ccagcaaagc ccataaaata gagctgtgct agcaacatga tgagttataa gaagataatc
     2041 aaaagcttac gctttatttt aatttaaaaa aatgattact gtaaagaaat cattttttat
     2101 tataatcact gatacatcaa atattctaaa taaaattttt atttatctgg aattgtatat
     2161 tttttctata atattaacta cagcgtacat tgcccaagca caaatagcca atacaaatac
     2221 tcccatcatt actaaatcta atttaaatac ttgagaacca tatactatca agtagcctat
     2281 tccatatctt gaaactaaaa attctccaac tattacacct acccatgcca taccaatatt
     2341 aattttagtt aaatttatta aatttcctgt gtttgcaggt aatatgagtt taaataatat
     2401 ttgagattta gtagctccaa agctttttaa catcttaatt ttttcttcat ctatattcat
     2461 aaaataatta taagctgaaa gtatagtaac aacaacagaa atcgttacag ctgttacgac
     2521 gattccttct attccagcac ctacccaaac tataattata ggagctaaag cagtcttagg
     2581 aagagcattt aaaactacca aaaatgggtc taatattttt gataattttt ctgaccacca
     2641 aagagcaatt gctaccaaaa tacctaatac agtacctata acaagaccaa gaacagtttc
     2701 atatacagat attccaatat gtttaaataa ttgaccacta aatgcatatt gaataaataa
     2761 attgtaaata tcacttggtt tgctaaatag aaatgtattt ataacattta agtcagctaa
     2821 aagttcccag attacaataa aaccaattaa aattaatagc tggtagaata atacatttct
     2881 tttttctctt tttacacctt taacatagtt tatatatcct tcagatcttt tattaagcct
     2941 catgtgtatc tagctccttc cataatatgt cgaaatactt ttgaaaatca ggaactttac
     3001 gtgttttgag aggcgttttt gttccatcca tgttaagttc aatatcgtaa atatttttta
     3061 tggtagctgg tcttttagat agtattgcaa ccttatctga tatgcttatt gcttctgcta
     3121 tagctaaaaa agtgcaacta attgcttaaa gaaacagaat tatccacttc agcacccata
     3181 taaacaatat taagatttcc taaactgcta tcccaaatga tactattaat aatagtagat
     3241 aataacaatc tcttatcatc taaactggca ttatcaactt catcattaaa tctcttcaaa
     3301 ttactaacaa taatatcaat attaatactg tcactactaa tattgatatt actagattcc
     3361 aaaatattaa tcttatcctt taaaatacta atctcattat ttaggctctc aatctgggaa
     3421 actatataat cagaagcagt actaccagta ttttttgcaa gctctataac taaattttta
     3481 ataagtcttt ccttatctaa aatttgattt ttaagtaaat tagtctcaga tttaaaaata
     3541 ttaaaaacat tatcagtctt aatgttatta ctattgaatg cacttataat agactcttct
     3601 ttacaattct taattttatc tataactaaa ctttcaacta atggaccatt aagattttta
     3661 cagttgcaac tatcagaccc aagtgttttt ttagtaccac aaatataata atactttaaa
     3721 tccttgtcag tttttttgcc tttataggta attctcatat tagaaccaca tttaccacat
     3781 tttataagac cagataaaag agcagttttt ccagttgata tccttggagt tttatcacga
     3841 tttttatcta attgattttg tacttcaagc catatttcag gttctatgac tccatggtgt
     3901 tttgcaattg ctgctattga gttagatgta tttttagcat aggtaaggat tccacatttt
     3961 ctatctggag tacctacaac atccatacca ctatttttaa ggtaatctaa aatttcatca
     4021 ttagctttta catatgctgg atttctaagt attctagata aagaactagg gtcaaattta
     4081 ccaccacgag gaccccttat tccattatta tagacatatt tatataactt agataaggac
     4141 ctaagttcta aatatttatt gtatattagc tttacaatct ccatttgttc atcatttact
     4201 tgaagcttat acatacttct ttcttttaga ttttcatcta agaatgtgat tttttcactg
     4261 ttgaatccat gaggtgtatt gcctccaagc catctaccac tacgggctaa ttcatacatg
     4321 ttgtctttta tacgttctgc tattgtttct ctttctaatt gagcaaatac acttgatata
     4381 aacatcatag ctcttcccat tggagttgaa gtatcaaatt gttctttgat agatataaat
     4441 gatatgttta gttcatttaa tttttctatt aaagtagaga agtcagatac atttctcgat
     4501 atcctatcta atctataaca aactaggtaa ctaaatttct tatctttagc atcctgcatc
     4561 attttcttaa attgtggtct atctatattg ctaccactaa atccctcatc ttcatatatc
     4621 aaaaaatctt ttacaccaat agactttgca taatcaatac ataattgtat ttgattttct
     4681 atagaatcac cttttccagt aaatcttgat tttcttgaat aaattgcagc tttcaaaatt
     4741 aaaacctcct ataaattagg atatatattt gaaattattt atatacaacc ttttaagtaa
     4801 acttattaga ataaatttat taattaggta aatttatata attctacttt ttataatata
     4861 tgactattta ttttatttct ttactattca agttctaaat caataataaa ttttgatatt
     4921 taattgtatc aggacaaatc tctaatttca tatattatta atataaaatc ataggttagt
     4981 gtgaaaaagt tgaaatttaa atattttaaa agataatttt ttggaactaa taggtataac
     5041 aaaaatttat agggggattg catatggaaa tcaatgttat agaaattttc cctaaagata
     5101 aagctaaact taataaaata gaaatggata aagctagttg gtttgtaaat ataataagta
     5161 aaaaatatcc taaagaagct ttaaatgaag catttagtat tttagaaaaa gaattaaata
     5221 taagtaaagc taatacataa gctttgatta ttgattttat atactattgg ttttatacgc
     5281 tatgacttga cattatatta atcaaatagt atatttttaa atatagcaca atgaagtgtt
     5341 aaaagagcaa tggagctcca tagataaagt ctatggagct tttttgcgta tttaacttaa
     5401 ggaggataga gctttgaata actttgagat taaaactaga ataaaatttg gagaaggttc
     5461 actaaaagtt ttgcaagaat taaaaaacaa aaatgtatta ataataacag acccttttat
     5521 ggtgaaatca aaaacaatag ataaaataac atctaattta ataaactcaa catatcaagt
     5581 ttttgaagaa atagtaccag acccaccaat agaagtagta gtagcaggaa tagaagcatt
     5641 taaatctata aatccagacg taataatagc attaggtggt ggttctgcaa tagatgcagc
     5701 aaaatctata atggactttt ctaaaaaaat attaaaaatt aacgaagtag agtttatagc
     5761 aataccaaca acaagtggaa caggttcaga agtaacatca tttgctgtaa taacagatag
     5821 tcaaaaaaaa tgtaagtatc cattagtgag tgatgattta cttccagata tggcaatact
     5881 agacccagag cttgtaaaaa ctgtaccaaa ttttataaca gcagatacag ggatggatgt
     5941 attgacacat gctatagaag cttacgtatc tacaaattct aatgactttt cagatgcact
     6001 agctgaaaaa tctataaagt tagtatttaa atacttaata aaagcatata aagatggaaa
     6061 tgacatagaa gctcgagaaa aaatgcacaa tgcatcttgt ttagcaggta tggcatttaa
     6121 ccaagcatca cttggcataa atcattctat tgcacatgta ttaggtggaa aattccatat
     6181 accacatgga agaacaaatt ctatattact tcctcatgta atagaatata attcatcaat
     6241 agtaggatat actaacacaa cttactctga tacagctaaa aaatatgcac aaatagcaga
     6301 attagtagga cttgggagtg ctaatataag aatatctgtt agaaatttag taaatgaaat
     6361 aaagaaacta caaaaagaaa tgaatatgcc aactaaattg acacaatgca aattaagttt
     6421 agaagatata actaatgaag aaagagaaat agcaaaactt gctataaaag atacttgtac
     6481 attaactaat cctaaggtac caactgaaga tgatataata aacatattaa ataacattaa
     6541 ataactacat tttattacat gtaaatataa tattatacaa atagggaaaa tgtttttaaa
     6601 aatataaatt atatattgac aaatataaaa cataaaacta taatgaaagt atcacaaagg
     6661 cgtgatactt tagtagaaag caatggagct tcttaggaat attaatatta ttcttatgga
     6721 gctcctttta ttttaagcaa atagcttttt aataaactat attcaaagaa agcagggaat
     6781 aaatttgact gaagaatcta agcaaagagt tattcaagaa tatgttcctg gaaaacaggt
     6841 tacattagca catatcatag ctaaccctaa tgaagacata tataagaagt taggattagt
     6901 acttgataaa agagatgcaa taggaatact tacaataaca ccaagtgaag cgtcaataat
     6961 agcagcagat gttgctacaa aggcttcaaa tgtatcttta ggttttatag atagatttag
     7021 tggttcagta gtaatatcag gtgatgtaag ttctgtagaa tcagcgttaa atgatgtttt
     7081 agaagtctta ggaaatatgt taaacttctc atctacaaaa atcacaagga cataataata
     7141 caatgaagaa tataatattt atgggaaaga caggtagtgg taaaactacc ttatgtcaaa
     7201 aactagacca gttagaatta aagtataaaa aaactcaatc agtggaactt tataataatg
     7261 caatagatac tcctggtgag tatatggaaa atagaaacct atataatgcc ttaataacaa
     7321 catcagcaga tgctaaaatt atagcaatag tgtatgatgc cacacaagaa gaaaattata
     7381 tagcaccagg ttttgccagt atgttttgca aagacgtaat aggaattata actaaaataa
     7441 ataaagctac tgaaaacgaa gtcaatatag cttatgaaag actatcacta gcaggagcaa
     7501 gtcaaatctt taaaatagac acagttgatg atattggact tgaaaaatta tttaaatatc
     7561 tagaaaaatc taaaaatata gatgaagttt aaggggaaat atttttttat tcaaaaatat
     7621 tattaaagta tgataaaata aaaaaatgta taaactattt taagaagatt taatctttaa
     7681 gcgaggtagg aacatgggga aaaaaatact attggttgat gatgaaccac tgttaaggat
     7741 ggatacaaaa gatatattag aaagtcatgg ctatgaaata ataggcgaag caagtgatgg
     7801 atttgaagct gttgaaatgt gtaaaaaaca caaacctgat ttagttataa tggatataga
     7861 gatgccaata cttgatggta taaaggcagg caaaataata tgtaaagaaa atctagctgg
     7921 tggagtactt ttattaactt catttgaaga taaagaatac gtagaaaagg ctaaaagtat
     7981 aggtgcttat ggatatttag taaaaacagc aagtgaaaaa tcacttatcc caaccataga
     8041 aatgtgttta aataaggtaa atgaatttga aaaaatgaaa aaagatttag aaaaagtaaa
     8101 ttctaaattg aatgaaagaa aattagtaga aagagcaaaa ggtatactta taagagagtt
     8161 taagatttct gaggatgaag catacactag aataagaaaa ttaagtatgg ataaaagaac
     8221 tacaatgatg gaaattgcca aaatgattat aataggatac gatgactaat acgataaaaa
     8281 aaatatcaac tgcacaaaca tacttaaata ataacgaaat tgaaaaaatt atagaagtat
     8341 caaaatcctt agatttaatg gcttcttttt atgaggctga tgtttttata gatgtactaa
     8401 gtaaatttga tgatgaagca attgttgtgg cacatggtag acctaaagaa aagtcaatgt
     8461 actgtgaaaa tgttataggt aaaaaggctt taattgaaaa tgaaccagga gttataaagt
     8521 gcttaaaaac aggagaaaga gtaagagata ttaaagcttt aacacaggaa tataaactgg
     8581 tcaaacaaaa tattcagcca ataacactag atgacaaagt tttagcagta ctaatagttg
     8641 aaaaagatat aagtagtgaa gttaagaatg agtttaatgc tagtgaagac gaagaaaata
     8701 aaaatttaca tcagtttata aaacttatcg gaaataatga ctttttagtt gataatttaa
     8761 attcagccat attaatattt gataaaaatg gaaaattaaa aattaaaaat cgtattgcaa
     8821 ctgagatata caaaaatctt gggtttggat atgatataca agatatgcat tacaatgatt
     8881 tagatataga aaccaacacc tttgaaaata tattaatgga tgaaaattat gatgagacaa
     8941 atgaagtttc aataggtaat atgtttttta aaataaagac catatacatc aaagatgatg
     9001 aatttaaggt ttgcaaaata gtacaagata taagtgattt aaagagaaaa gaagaagaat
     9061 tagttttaaa aacagtggct ataagagaag ctcatcatag agtaaaaaat aatcttcata
     9121 cagtaatatc tataataaaa aaacaaagta gattatctca aaatgatgaa gtaaagcagt
     9181 gtttagataa cataataaac agagtatttg caatactttc aactcattat ttactatcta
     9241 aagaagttga taataatata tctatacgag aaggtatcaa tttattagtg tcaaatattc
     9301 aaggtggcta tttatttagt aaggatatag atatacgtat aactggtgaa gattttaaaa
     9361 ttagtggaga aaaagcaaca gcaatacttt tggttataaa tgaaatacta caaaattgtt
     9421 atgaccatgc attttcggat agagaacatg gtactataca aatattaata aataaagata
     9481 acgactatag aaatattgct attatagatg atggaattgg atttgatagt aataatataa
     9541 ataaaaatag cttagggaca tatataatag atagttatat aacacagatg ttaaaaggaa
     9601 atatagagag aaaaagtaat gagaatggta cagaagtatt aattactata cctacacaaa
     9661 ttaatattta aataataact catctacaaa gtagtagttt taattgagca aagaggctta
     9721 aggttattaa tagattaagt taattgaatg tatttataaa aattataagt atatattcaa
     9781 tttaacaggt atttattata actttaagcc tctttgcttg tttaagacat acttaaattt
     9841 taggaggtga gaaaatgaga gaagagttat taagtgttgg tattgacatt ggaacaagta
     9901 ctactcagtt aattttttct aaattaatag tagaaaatac tgaatcaaat ttttcggtac
     9961 ctagaataag tatagtagac aaagaaatta tttataaaag caaagtttat ttcacccctc
    10021 ttatttcaaa taatgaaata aatggtcaac aaataaaaga tatagttgaa aatgaatata
    10081 aaaaagcaaa tatatctaaa gaggatatac atacaggagc agtaataata actggtgaaa
    10141 cagctagaaa agaaaatgca aatgatgtac ttcatacttt gagtggattt gctggggact
    10201 tcgttgttgc aacagcagga cctgatttag aaagtataat atcaggaaaa ggagctggag
    10261 ctcatattta ttcaaaagaa cattcaacta caattgtaaa tatagacata ggtgggggaa
    10321 ctagtaacat agcctcattt aaaaggggag aagtaaccga tactgggtgt ttggatatag
    10381 gtggaagact tgtgaagata gataaaataa gtaaaaaaat aacttatata tcacctaaaa
    10441 tagataaaat cataaaagat aataatttaa atcttcaagt aggcacaatg gctactgtag
    10501 aaaatacaaa gccaatagtg gatataatgg ttgacttatt aatggaaagc ataggattaa
    10561 agaaacagac acctttgttt gattttataa taaccaataa atcaataagt atagatgaaa
    10621 atattaaaaa tgtttcattc tctggtggag tagctgatta tatttactat gatggagaaa
    10681 taaaagatta ttttgaatat ggtgacttgg gaattttact tgggcaaaca ataaaaaatt
    10741 gtgaatacct taaaaaagta aatgtagtta aatctatgga aacaataaga gccacagtgg
    10801 ttggggcagg ttctcatact actgaagtaa gtggaagtac aataacttac actagcgaaa
    10861 agtttccact taagaacttg ccagttttaa aattatcagt tgatgaagaa acaggtactt
    10921 caaaacaaat cagtgaagct ataaaaaata aacttaattg gtttaaacta gaaaatgatt
    10981 tgcagaaagt tgctatagcc atgataggaa agaaaaatcc aaccttttta gatatacaag
    11041 agtatgctaa agggtttgta gatggaatgc aacaaatcat agaaaatgat ttacctttta
    11101 tagtaattgt tgaaaatgat atggcaaaag tgttaggtca agcaatatat gcattattaa
    11161 attatgaaaa agaaattgtt tgtatagaca gtgtcaaggt tgaaaatgga gactatatcg
    11221 acattggaaa acctatagtt gaaggtaaag ttttacctgt ggtaataaaa acattagttt
    11281 ttaattaata gaaggaggta agtaaatgat tttaaataca aaattatttg gacgtactta
    11341 tcagtttaaa ggcttatatg atgtaatggc taaagctaat gaagaaaaat caggagataa
    11401 attagcaggt cttgcagcag aatcagctga agaaagaata gcagcaaaag ttgttttatc
    11461 acacataaaa ttggaggata taagaaataa tcctgcagtg gcatatgaag aagatgaagt
    11521 aacaagaata atacaagatg ctgtaaatga aaaagtttat gaagaaataa aaaattggac
    11581 agtatctgaa cttagagaat ggctattgga ttcaaatact acaagtcttg atataagaag
    11641 aatatcaaga ggattaactt ctgaaatgat agcagcagtt gcaaaattaa tgtcaaatat
    11701 ggacttagtt tatgcagcta aaaagataaa ggttactgct cactgtaata caactatagg
    11761 agaacaagga acattatcag caagacttca acctaatcat ccaacagacg acccagatgg
    11821 aatacttgca tcacttcttg aaggtttaac ttttggtata ggagatgcag tacttggatt
    11881 aaatccagtt gatgactctg ttgagagcgt tactaaagta ttaaaaagat ttgaagaagt
    11941 aaaacaaaaa tatcagatac caactcaaac atgtgtattg gcacacgtta ctacacaaat
    12001 ggaagcaata agaaatggtg ctcctgcaga tttaatattc caatctatag caggttctga
    12061 aaaaggaaat gaagcatttg gatttaatgg cgacactata gaagaagcta gacagttagc
    12121 tttaaaacac ggtacagcta caggacctaa cgttatgtat tttgaaactg gacaaggttc
    12181 agaattatct tcagaagcac atcatggaat agaccaagtt actatggaag ctagatgcta
    12241 tggatttgct aaaaagtatg aaccattctt agtaaataca gttgttgggt ttataggacc
    12301 tgagtactta tatgatgcta gagaagttgt aagagcagga cttgaagacc actttatggg
    12361 taaactacat ggcttaccaa tgggtgttga tgtttgttac actaaccata tgaaggctga
    12421 ccaaaatgat atggaaaact tagccatact attaacaaca gcaggatgta cgtattttat
    12481 gggaatacct catggagatg atgttatgct taactatcaa acaacaggat accatgaaac
    12541 agcatcactt agagaaatgt ttggactaac agcaataaaa gaatttgatg cttggatgga
    12601 aaagatggga ttctataaag atggtaagtt aacagagttg gcgggagacg catctgtatt
    12661 attaggatag gaggtattta atatgaatga gaaggattta aaagcattgg tagaacaatt
    12721 agttggacaa atggttggag aattagatac taatgttgta tctgagactg ttaaaaagac
    12781 aactgaagtt gtagtagaca acaatgcttt tatagatgat ataacagaag ttgatataag
    12841 aaagcaatta ctagtaaaaa atcctaagga tgcagaagct tatttagata tgaaagcaaa
    12901 aacacctgca agattaggta taggaagagc tggtactaga tataaaacag aaacagtttt
    12961 aagatttaga gcagaccatg ctgctgcaca agatgctgta ttctcttatg tagatgaaga
    13021 atttataaaa gaaaataata tgtttgcagt ggaaacttta tgtaaagata aagatgaata
    13081 cttaacaaga ccagatttgg gaagaaaatt ttctcaagaa actataaata atataaaatc
    13141 taaatttggt acaaatcaaa aggttttaat attagttgga gatgggctta gctcagctgc
    13201 aatagaggca aatttaaaag actgtgtgcc agctataaaa cagggtctaa aaatgtatgg
    13261 tatagattca agtgaaattt tatttgttaa acattgtaga gttggtgcta tggaccactt
    13321 aggtgaagaa ttaggttgtg aagttatatg tatgttggtt ggagaaagac caggattagt
    13381 tactgctgaa tcaatgtcag catatatagc ttataagcca tatataggaa tggcagaagc
    13441 aaaaagaaca gttatatcaa atattcacaa aggtggaaca actgcagttg aagcaggtgc
    13501 tcatatagct gaacttataa aaactatgtt agataaaaaa gcttcaggaa tagaccttaa
    13561 ataaagtcga gggagtgtag aatatgaaaa atgatgtaat tcgtcctaat atactaggaa
    13621 ttaaaataat ttcgaatata agtccagaaa tggcacaaaa actagaatta aaatcacatc
    13681 acaaaagttt aggtttaata actgcagact gtgatgatgt tacgtataca gctcttgacg
    13741 aagcaactaa agcttcagag gttgatgttg tatatgcaaa atcaatgtat gcaggtgctg
    13801 caaatgcttc aacaaaactt gctggtgaag tattaggaat aatagcaggc ccaagcccag
    13861 cagaagtaag aagtggtcta aatgcagtag ttgattttct agagtatgga gcaactttta
    13921 taagtgcaaa tgatgatgat tcaatagcat actatgctca ctgcgtatca agaacaggta
    13981 catacctttc agagatagca ggaataagag aaggtgaagc attagcttat ttagtagcac
    14041 caccacttga agcaatgtat gcactagatg cagcaatgaa agctgcagat gttaagatgt
    14101 gtgaattatt tgcacctcca actgaaacaa actttggtgg agcattactt acaggttctc
    14161 aatcggcttg taaagcagca tgtgatgcat ttgcagaagc agtaaaatca gttgcagaca
    14221 atccaacagg attttaagga tagttagatg gatgctatag gcttaataga agtaatagga
    14281 tatgttgctg caatagaagc ttctgatgct tgtttaaaat ctgcaaatgt taatattgta
    14341 agaattgata aggttggggc aggtattgtt actttaacaa tatgtggaga tgtcggtgct
    14401 gtaaaagctg ctttagaagc aggtgaaata gcagcttcca gagttggtac attaagaaca
    14461 tcacatatta taccgagaat ccataatgaa gtaacaaatg ctttattcaa aactaaagaa
    14521 cctaaagtct gtgaagtttc agaagataaa gaaaaaaact ttgagattac attggaaata
    14581 actgataatg tatcgaaaaa tttatcagaa aaagaaaatg taattttaga tgtcaatgaa
    14641 aacagtggag atactgaaaa tttatatagt gatatagata aaacaaacaa aaaaattgaa
    14701 acagttgatg atagtttaac agaagctaat gaggaaaaaa tagaaaatac taatgataaa
    14761 gaagtattgg aacaagttaa aatagaaaat tccgattttg atagagatga cctatcaaag
    14821 aacagtgtaa aaaaacttaa agctatggct aagaaattag attcttcaat aacttataaa
    14881 gatttaaatg ttcttaaaaa agaagaatta ataaacttag ttaaaaagct tagcagaagg
    14941 gatagatagt tatgacactt ttagataaag atttagtatc tatacaagaa gtcagaactc
    15001 ttgtaagaag atctaaagtg gctcaagaga aactttctaa aatgagtcaa gagcaaatag
    15061 ataaaatagt aaaagctgtt gtagatgcag catttaataa tgctactaaa ttagctaaaa
    15121 tggcaaatga agaaactgga tttggaaaat gggaagataa agtaattaaa aatacttttg
    15181 catctatggg agtttatgaa actttaaaga acacaaaaac tattggaata attggtgaag
    15241 ataaagaagc caatacgata gatatagcta caccagttgg agttgtggca ggtcttatac
    15301 cttcaacaaa cccaacatca acagtaatat acaaaactat aatatctcta aaagcaggaa
    15361 atactatagt tttctctcca catccaaatg caaaaaactg catacttgaa acagttaata
    15421 taataagtga ggctgctata aaggctggag ctccagagga ttcaatatta tgtataacta
    15481 atccaagtat agttggaacc aatgaattga tgaaacataa agatacaaac ttaatactag
    15541 caactggagg agaagcaatg gttagagctg cttactcttc aggaacacca gctattggag
    15601 ttggaccagg aaatggacca gcatttatag ataaatcagc aaatgttaaa ttagcaatca
    15661 aaagaataat agattctaaa acttttgata atggtgttat atgtgcatca gagcaatcta
    15721 tagtaataga aaaatctatg gaagaaactg ttttaaaaga gcttaaaaat caaggtgcat
    15781 atgttttaaa tgaagaggaa agtgaaagat tagcaaaatt catattaaga gctaatggta
    15841 ctatgaatcc acaaatagtt ggtaaaagtg ttgaggtaat agcaaattta gcagacttaa
    15901 caaatatacc taaaaataca aaagttctag ttgcaagaga aaataaagtt ggtcacaatg
    15961 tagcctattc aagagaaaaa cttacaccaa tactagcgtt ttatgttgaa gaaaatgtag
    16021 aagctattat gaacagatgt agagaaatat tgttaaatga aggtgcaggt catacattct
    16081 caatgcatgt aaatgatgaa gaattggtaa aaagatttgc ccttaatatg ccagtatcaa
    16141 gaatacttgt gaatactcct tcagcacttg gaggaatagg tgcatcaaca aaccttgtac
    16201 cagcactaac acttggttgt ggtgcaatag gtggaagttc aacttcaaac aatataggac
    16261 cacttgattt aataaatgtt aaaagagtag cttatggaat caaagaaata gaagaacttg
    16321 gaagagataa atctcaagtt gaaaaatcaa tgtttgactc aatggataaa gaagaattaa
    16381 taaatcttct tgttcaaaaa ctagtcaaag aactagcata actaaaataa acaatgaaac
    16441 ttatggctat cgctataaat ttataaaaat ataaactata aaaaactata aaattaaatt
    16501 tttggaggat aagattatgg caagtgcaaa cgcattagga atgatagaaa ctaaaggatt
    16561 agtaggagca atagaagcag cagatgcaat ggttaaagct gcaaatgtac aattagtagg
    16621 aaaagagcaa gtaggtggag gattagttac tgtaatggta agaggagatg ttggagctgt
    16681 taaagctgct acagatgcag gagctgcagc tgccgagaga gttggagaac taatatcagt
    16741 tcatgttata ccaagaccac actttgaagt agatgctata ttaccaaagg tatcagctga
    16801 gtaatataag aataatttta aaatttaaat tttgattgaa aaagaggcta tctcaaaaat
    16861 gagtcttact aataaactca atgtattttg aggtagtctt ttttatacat ctaataggag
    16921 atgtgataaa atgggtgttt taacagaaaa cgaagtaaaa agaaaaattg gaaaaaacaa
    16981 aaataatata actgaatttt atatagaaaa aggtcaaata ataactcctt ctgcaaaatc
    17041 ttatttagct gagagaagta ttgagcttaa atatgttgat aaactttcag atgtaaacaa
    17101 tgaacctaaa gaagttgtaa aagaagtagt taaagagaaa aaatataaat atactactgt
    17161 atttggcgct aaattggatg aaaaaccaga acatatgact caattaaatg gaaatctttt
    17221 agtttttaaa gaccataaaa gaataatatt gagaggaaaa atagattctc ttgaatcaga
    17281 aatactaaag gtacagatac tttgtcagaa actagatatg ccaaagcttg ttaaggaatt
    17341 gcaagaagta ttagactttg taagaaatat aatgagatgt gaagttttag atgaaaagct
    17401 agaagacttt aaacttttag gattaactcc tcaagaactt agagaacaat ctcactatcc
    17461 taaaaaatac tttggtatag gacatgaatt cccaagttat gaaatgggag aagtagtagt
    17521 agctataaat agtataagaa gtaatacacg agaggttgaa cttgcagcct atgaagcatt
    17581 taagggtgag tatggaaatg ttcacagaga agatttaata aaggcactta atagattatc
    17641 gtcagtattt tggataatga tatataaggt tagaactaat aagtataagt agttggagga
    17701 cataatggag aatctattaa atgaaatagt ggaagaagta ataactagag ttaaaaaaga
    17761 agcatttata gaagttgaag catcaggaag acacgttcac ttaagtagag aagatgtcga
    17821 taaattattt ggagaaggat atactcttac aaaactaaaa gacctatctc aaccaggtca
    17881 atatgcatgt aaggaaagag ttacaataac tggtcctaaa ggaagtataa aaaatgtagt
    17941 tgtacttgga ccatgtagaa atgaaactca ggtagaaata tctttaacag atggttcaac
    18001 tcttggacta aaagctccta taaaacaaag tggagactta gaaggtactt taagtattaa
    18061 aatatcaaca caatatggtg aagttgaact tgataagggg ttaatggttg ctaaaagaca
    18121 tatacacatg actcctaaag atgctgaaaa attcaatgta tgtgataaag agatagttga
    18181 agccaaggtg atgggtcaaa gacctttaac atttgatgat gtagtaataa gagtgagtga
    18241 cagttttaaa acttatatgc atatagacta tgatgaagcc aatgcatgtg gttattcaaa
    18301 aggaactgtt gctaaaataa taaagaaagc ataaatttaa cctactatat aaattacctc
    18361 tagggaggat ttaatatgaa ttatgataac cttgtagatt taataacgga agaaatctat
    18421 aaaaaaataa atagtaatga aataaaaata tctaataaac ctaaagctgt gattgtattt
    18481 gaacaagata acaataaatt taacttatta aaagatgaat ttgaaatact agaatttgat
    18541 aaaagtataa gggaatgtga aatagtgata gtttcaagac tttgtatgag ggggctatcg
    18601 aatatagcac ttggaaattc aacaagtgat gaagaaagat ttatactaaa aatgattatg
    18661 aaaggcaaaa aagtatatgt cctagatgaa ggaattgaat acaaaaaata taaggatact
    18721 gcaccaaaag cattatataa gaaatttatg tcatttgaag atgaaatatg taaatttggt
    18781 gtagaaatta taaaagactt aaatgttata actaaaaata agttaaatat aaagaaagaa
    18841 ctagaaagta ctagaggttc taaaaaagaa gatacaaaag ttttagataa agatgtttta
    18901 aatttaacca gtgtagaaag tgtaaaaata gataatgaat ttagtttgga tttaaggaat
    18961 aaaaaactta tatcggaagc tgacttaaga aaaccaacta taaatggagt taaaaacata
    19021 ttagttaata aaaaaagtat aataacacca ttagctgtag attttatgag aatacaccat
    19081 ctcaaactaa agaaactgta aggaggtaat tttatggata taggaaaagt tgtaggtaat
    19141 gtttgggcta caagaaaaga tgaaaaatta tgtggccaaa aacttttagt tgtaaaaatt
    19201 ttaaaaacta aagacacata caaggaaggc ttcatggttg cagccgataa tgcaggagca
    19261 ggaaatggag acttagttct tatatccaaa ggttcctcag ctagagagtc gattgaaaaa
    19321 tctcatgttc cagtagatgc aactatagtt ggagtagtcg attcgtttga ggtgtttgat
    19381 gaataaaagt ataggagcta tagagtttaa aagcattgct aaaggtatag aagtatccaa
    19441 tgaaatgata aagaaatctt cagttgatgt attgtactta aaaagtattt gcccaggtaa
    19501 atttctaata atagtaggtg gagaaacttc ttatataaat gaatgtgtag attatggaat
    19561 aaaacttgga gaaggatata ttgtagataa cttcgtaata aatgcaattt cacaagaaat
    19621 attagatgga tttaaaaata agtatcaaaa gctagatagt atagtctcta taggcgttgt
    19681 tgaaagtagt aaagtatgcg ctggaataaa aatgcttgat aagactttaa aatctggcga
    19741 cttagtatta gtaaaacttc aattatcttt tgctataggt ggcaaattag tatatgtagt
    19801 agcaggagat ttaagtagtt tagaatatgc attaaaagaa agtgaaaatg tagtaagaga
    19861 aaaagaagta atatataaga ctgtaatacc atcagtagac agtcaaataa taaaaagtct
    19921 aataaaataa tggggggaat tatgagtata aacgaaatta taatctatgt aatggtagtc
    19981 ttcatggtac ttggagctat agataaatgt ataggtaaca aatttggtct tggagaacaa
    20041 tttgaagaag gtataatggc aatggggtca cttgcagttg caatggttgg tgttatatgt
    20101 ttagcaccag ttcttgctga tgtattaaga ccaattgtag taccagtatt taatatactt
    20161 ggagctgacc cagctatgtt tgctggaagt ttattagcta atgatatggg tggtgcgcca
    20221 cttgcacttg aacttgcgaa agaccctaat tctgggttat ttggtggatt aatagtaggg
    20281 gctatgatgg gacctacaat agtatttata ataccagttg cgcttggaat aattgaaaaa
    20341 gaagaccaaa aattcttagc aacaggaata cttgcaggta taataacaat acctattgga
    20401 gcattcgttg gtggattagt tgcaggattc gaggtaatga tggttcttag aaacttagtg
    20461 ccaataataa tatttgcagt agttatagca cttggattat taaaattcga aaatgctatg
    20521 ataaaaggat tcacatactt tggaaaaggt gtagtaatag ttataacttt aggacttgct
    20581 gctgccatag ttgaagcttt aacaggaata gttgtaatac ctggaatgaa accaatcagt
    20641 gaaggtatag aaatagttgg agatatagca atagttttag caggagcatt cccattagtg
    20701 tttgttataa caaaggtatt taataaacca ttaatggctt taggaaaagt tcttggaatg
    20761 aatgatgtat cagcagcagg ccttgttgca agtttagcta actgtatacc aatgtttggt
    20821 atgatgaaag atatggacaa tagaggaaaa ataataaatg tagcattctc tgtatcagca
    20881 gcattcgtat ttggagacca cttaggattt acggcaggat ttaattctaa tatgataaca
    20941 ccaatgatag ttgctaaatt agttggtggt ataacagcag tattgttagc tatggttatc
    21001 gcaaataaga cactaaggaa ggagaatgta taagatggat atatcaaata tagataaaaa
    21061 tttaattgaa acattagtaa gacaaataat agaagaaaaa ataagtggaa ctaaagacac
    21121 agtagatttt gttagaaata aagacattag tggaataact tctataaagt taccaactgt
    21181 aaaagttagt gaatctgata gattagatac agggaatcca agtgatgtag tttacacaaa
    21241 agatttattt acattagagg aaagcccaag attaggttgt ggtatgatgg aaatgaaaga
    21301 aacaactttt gattggactc taaactatga tgaaatagat tatgtaatag atggaacttt
    21361 agatataata atagatggaa gaaaggtttc tgcttcttca ggtgaattaa tattcatacc
    21421 aaaaggaagt aagatacaat tttctgtacc tgattatgct agatttatat atgtaacata
    21481 tccggcagat tgggcatctc aaaattaata aaaatcaagt taagttaata ataatcaaat
    21541 aaataattta aaatacaaac tcttaaataa acacacatat ttaaaaaagc tatgaattaa
    21601 aattcatagc tttttttata aagaatgtta tattttagac gtattttttc tatatttact
    21661 gggagacata ttatattttt tattaaataa tctaataaaa tgctctacat ttggataacc
    21721 aatactattt tactgataat cttttcctta tcactaatct tacattttaa aatattattt
    21781 ttactcgtaa tattatcata agaatttgtt tcttatttaa aactaattag aattataaag
    21841 tttattgcca tgttattaat aaaataaatc cagttaaatc gagtgctagt taaagtaata
    21901 agaaactttt acaatggttt cctttatcga ttgaaataaa agttaatatg gtataatatc
    21961 taaagagaga atcttatcaa ttagaatatg catagaaaca agtggcttaa aaggagacgt
    22021 tatatggaag agatagtaaa gaaggaacaa gcaagtatga atgatatttt tttgtatctt
    22081 aaagctaaat caaactcatt atataaattt gtaatattat ataatgagtt tatcaataaa
    22141 cctaaagatt atggaactgg ggaacttata aacatggttg aagtacatat gctaacagcg
    22201 attgaagaaa atccaggaat aagtccaact cagttagcta aaatatggaa cagaactaaa
    22261 ggtgcaatat ctcaaactat atctaaattg gagaaaaagg gttatataac taaagaaaag
    22321 aaagaaggaa atgcaaaaac tatattacta tatccaacca catcaggagt agagttaagt
    22381 aaggcacata aactatatga caccatagat gttacaagaa catttgaata cttaatcaag
    22441 gagtgtacat tagaggagat agatagtttt tataaagtaa ttgatttgtt tattaattta
    22501 ttagaagaat ctccgcagga aaataatgat tctgaaaaag tgtagctaag attgaagttg
    22561 aataaagaga aatagatatt atagaagtag tacttaagta cacattatat aaaaatataa
    22621 taggtatagg attaaaaagt ttagtggttt aaagtttaac cactaaactt ttttaatgtc
    22681 tataatctac tattatttaa tttactaaaa ataaaaaaac tcattatatt aagatgaaaa
    22741 tagaaaaata actagaaaaa tactataata tatcagctta atacagaaaa aagttaaaaa
    22801 tattgagaaa aataaaaatg aaaacgtttt atattgacat agagaaaaag tagtgatacc
    22861 atttaaatat agtttagtag ctaaactata tttaaattat aataactatt ttagggggat
    22921 gttatgaatt taaaacaatt aagtgaaaaa tacgaagaat atgtaattca aatgagaaga
    22981 gaatttcata agtatccaga attatctttt aaagaaataa gaacaaccca aagaataagg
    23041 gaagaattac aaaaaatagg ggtccctttt gtatctattg aaccaaatat cgtaatagct
    23101 actatacaag gcaaaaatga aggtaagaca attgcaatta gaggagatat agatgcgctt
    23161 ccaatgcaag aagattcaga tgttgaatac aaatcagaat atgatggaat aatgcattct
    23221 tgtggacatg atgctcatgg agctatgtta ctaggacttg cacatatgct aaatgatata
    23281 agaaaagatt taaaaggtag agtattatta gtttttcaag cagctgaaga agttggtggc
    23341 ggacacaagg agataataca gtactttaag gaaaatggag gaccagatag attaatagct
    23401 actcatgttt ggtccgatat tgaagctggt aaaatttctg ttgaaccagg acctcgtatg
    23461 gctggtgggt ctggttggag aatagacata acaggtagag gaggtcatgg ttctagacca
    23521 gatcaaagca tagatcctat aaagccagct tgtgatatag ttttaaaagt atcttctata
    23581 ccagttaatc atataagtgt actagaacaa tgtgttgtac atgcatgtgc aatacatgga
    23641 ggaactacaa taggaaatgt tattccaaac aatgcagagg taataggtgg atatagatat
    23701 tttactgaag aatcaggcaa aaaagtgttt gacattataa agcaaatgag taatggtgtt
    23761 ggacaagctt atggagtgga tgtgaaggtt actcatactg gaggcatagg acctgttatc
    23821 aatgatgaag aagcagttaa gatggctaaa gaaatagttt ctaatataga tggattggag
    23881 ttagattctt atgagccaat atgtgcatca gattgttatg gtgaaatatt aaaagagtat
    23941 tctggttttt attgttatct aggggtaggt aacaaagaaa aaggaataat atatgcacaa
    24001 caccatccta agtacaatat agatgaagat acattaaagt taggttgcga atttatggct
    24061 aaatatgcag ttgaattttt aaataaaaat aataactaaa ataaatcgaa ttttataaat
    24121 gggggggatg aaaatgcaag gtgcattaaa ggaaaataag aaaaaaagtg gtggaggatt
    24181 tttaggatgg attgaaagag ttgggaataa aatgccacat cctctagcat tatttacata
    24241 tattacattg atagtagtag cattatctgc aatagcaagc tttttaggtt tttcagcaac
    24301 aagtcctgct acaggaaagt taataaaagt tatgaactta ataagtgcaa aaggtttagt
    24361 actatttatg caagagtttg ttaagaactt ccaaaacttc cctgtgcttg gggtagtttt
    24421 agttatggca gttgccacag gagtttgtga aaagacagga tttttttcaa ctgccataaa
    24481 aatgagttta tcaaaagtta aggggaatgc ggttgtattt ataatagctt ttataggagt
    24541 atttgctaat caagctggtg atgctgcttt tgtattagta ccaactcttg caggagcaat
    24601 attttatgga ttaaatagaa atccattagc tggtatattc tgtggatttg catcagttgg
    24661 tggtggattt gcaacagctg taattcctgg gggatgggac gttacgctaa cgccaataac
    24721 tgtatcagct gctcaaacta ttcaacctgc atttgatatg acattattag ctagttatta
    24781 tgcactattt gtatctgcgt ttatagtagc tacagtatca acaatagtaa cggttaaatt
    24841 tatagaacct aaattaggta agtatactgg taaaccagaa ggtatagatg ataatcaagg
    24901 ttttgaggtc acaaaagaac aagcaaaagc agcaaagtta gcaggtttta cagttttagc
    24961 ttatgtagcg ttattaattg ctttgtgtat accagctaat agttttttaa gaagtccaga
    25021 aggttcttta atatttggag caccacttat gtcttgctta cagtttttta tagtaatact
    25081 attcttcttg ccagggattg tgtatggaat gagggttggt aaaatcaaga ctgtaaaaga
    25141 cttaaatgat atattatgtc aatcaatggc agcaatggca ccgtttatcg tacttgcaat
    25201 agttataggt caattcttaa cgctattctc agtgtctaat ttagcacagg tactagctat
    25261 aaaaggtgga gcattactca actcattgcc actaccacca caagttataa tactgctatt
    25321 cttagtacta gtagcgttta taaatatatt tgttataagc ggaagtacaa aatggatgat
    25381 atttggacca gtatttgttc cgatgttaat gcaattaaac atacatccag catttactca
    25441 gtttgtatat agattaggag attctgtaac taatcattta tcaccattaa atgcattctt
    25501 tataatactt ttagcaacag tccaaaaata cgataaaaat gcaggtatgg gaactatatt
    25561 ctcagctatg ataccttaca ctataggtta ctttgtagta cttgcagttt tagtagtagt
    25621 ttggatgaca ataggtatac cagtaggaat aggtggacaa gtttggttat aaaacatatt
    25681 taataatttt gggaggaaag aaaatggaaa caactgaaat aagatacaat tttgatgaag
    25741 taatagatag aagtggaaca aactgtctta aatatgatct taagagtcaa tttatgccag
    25801 aatctccaga agatgcacta ccactatggg tagcagacat ggattttgca tgtgctcctg
    25861 agataattaa tgcaatgcat gaaagaatag acagaaaaat atttggatat agctctcaac
    25921 aaactgatga ttattatgaa gctgtatgtg gatggtttaa gagaagattt gattggaaaa
    25981 tagaaaaaga gaatatattc tttagcccag gggttgtgcc tgcgttagga tttttcatac
    26041 aaatattaac acaaaagggt gatggtatca taatagaaaa gcctgtatac tatccttttg
    26101 aagataaaat aactaataat gaaagaaaag tagttaatag tcctttaaag tttgaagatg
    26161 gtcattattc tatggattat gatggatttg aagaattagc taaagatgaa aataataagg
    26221 tgtttatatt atgtagtcct cataatccag ttggtagagt atggaaaaaa gaagaactta
    26281 gaaaaatagt agacatatgt aagaaatatg atttgtggat aatatctgat gaaatacatt
    26341 gtgatattat tcgtaaaagt gaaaagcata taccattaga agtagcatgt cctgattata
    26401 aagatagaat aataacttgt acagctccaa gtaagagttt taacttagct ggtatgcaat
    26461 tatcaaatat agtaatcaat aataaggaat tacaagaaaa atggatgctt gaaacagatt
    26521 ctaaattagc tatattccta cctaatccat tcgcaatagt tgctactaaa gttgcttata
    26581 atgattgtga agattggatg aatcaagtaa atgagtatat agatggtaat attaaatatg
    26641 tagaagattt tgttaatgag tatatgccta aagtaaagat aataaaatct caaggaactt
    26701 acttaatttg gttagacttt agagggtatg gattagatgc aaaacagctt gaatatgtaa
    26761 tgcttaacaa ggcgaaggta ttgctagatg aaggatacat attcggagaa gaaggagcag
    26821 gatttgaaag aataaatgtt gcttcgccta gaacaattat agaagagtgt atgaatagaa
    26881 taaaatgtgc atttgaagga ttataatagt aatatctaaa taatatattt gtgtatttta
    26941 aaaaaagact atgttaaaaa aatatttcaa agcatagtct tttaaagttt tatgatgagt
    27001 ttaaaaaatt tcaaaacgtt actattattg ataatcttca cttatatgtt tatattagaa
    27061 ataattccac aatatgctca ttttctaaag ttgcactttt atacaccttg cttcaccaat
    27121 atcatgtgta accaaaatag tagacttatt ctcattctta ataatactat aaacatcatc
    27181 acaaactaat aatctagtct gataatcaag agctgaaaaa ggttcatcta aaagtagaat
    27241 atctggattt acagaaagtg ttctaataag cgcaactctt tgtctcatac ctccagataa
    27301 ttcttttgga tacatacttc taaaatccca taatccataa gtctttaaaa ggctttcaac
    27361 tctatctaaa gattttttat cttttttgcc ttgaatttcc aatccaatag ttatattatc
    27421 cattatattt ctccattcaa gcaaattatc tttttgaaac atatatccaa tatttccagt
    27481 aatctttata tcaccactag tcggttttaa aagattagta agaatattta atattgtaga
    27541 tttaccactt ccagaaggac caagcaaagt taatatttct ccttctttca agttaaaatt
    27601 gacatccttt aatacttcaa gctcgccttc cttagtgtag aagttcatat ttatattttt
    27661 aacttctact atgttgtcat tcattatgcc accccctata acttttagct cgtatatatt
    27721 atgttattaa caatatgacc tatttgtacc atttttcata aatataatat aaatattttg
    27781 tttatttacg tattttctta gtaacttgta cgtataaatt ataataaata aattataagg
    27841 taggggataa atttgagtaa cataataacg aatttaatag agtcagtatt tactaatcca
    27901 ataactatat tgtttttact tgcaataact gtgtattctg tttttaaaat aatagaaaat
    27961 aacagagtat attcatttgt aagttcaaaa ttagacgaaa tcaatagaga ttataagaca
    28021 agtgagtttt ataaaaaggt aagggatgac tactatacat atagtaaaga aaatccttat
    28081 gcagacgtaa atataacttc atttatagag gaagttgtat ctgatttaaa gcataataat
    28141 ttgccattgt tagaaaaaat tagaagtata aaaaattcat cttcaataag tatattactt
    28201 ggggttttag gtacgtttgt tggtctttct acaatgcttt tatgtgttga tactaaagac
    28261 attataaatt cacttccttc aactattagt agtatgcaaa ctgcatttac aactagtata
    28321 tttggagttg tattttctct aattataggt tactttacta agataaaaga ttgtgaacat
    28381 gttttgatac aaataatgtt aaaatctgaa aatttactaa catctgaaat aactcatttt
    28441 aagtcagaaa gaatggattt aaaagtagaa gaggtaaaaa atacaataaa acaaataagt
    28501 aagtctatag aagctattga aaaatttgat aaaatatcta aagatttaaa tgactttaat
    28561 gatgaattta tcagtggtat agaagcttta aaaagccttt tagaaggttc tcaaagttct
    28621 attaagacat ttgaccagag cgtaagaaaa ttagataaac agtttaatat tttaaatata
    28681 aaatttgtaa agctttttga taaatatgat aatcaagata atataaataa agagatttta
    28741 tttgatataa aagaatcttc aaaaaatata tacaatgcca ctgaaagcca attcaaaatt
    28801 agagattata taaaaaatat aaatgcagga tttgctctat atgaaagaag tgctcaagat
    28861 ttattaacta aattaatgac ccatgaaaat aaaatctctc aaaatcaaaa aatcctttta
    28921 gatgaaaagt ttaccttaga tgactcaata aaaaatctct caagtattat tgaaaacttt
    28981 tctaatgacc tacaagttaa actggatatg atgtttgaaa attctttaga tattcaagat
    29041 aagttagatg ttatgtttaa taactctttt atgaatgatg aagttcctct tgatagtgag
    29101 gaattattta aggatgatgt taataatgta tttaatcctt ttagtgaaga aatttatgag
    29161 atagaggata aagaaataaa ggtcataggt gaggatgagt taaatgaata ataaatatag
    29221 aagaactgtt aacagagaat ttgaaaagag tagcttttgg ccaacattta cagatttatt
    29281 atctactgta ttgatggttg tgattcttat cttatttagc tcagaaagta tttcaggttc
    29341 tgttgaacaa gatttagcta agaatgtcaa tgcttctgtt gaagaaactt ttaaaaaaag
    29401 caaaatacct gtgaaggtag ataaatctaa tgggcaagta acttttggtg aaaaaaccat
    29461 gtttgatgta gatagtgatg ttttaaaacc agaggctaaa gaaatgctaa aaatgtttgt
    29521 tccaaagtac atagagacta tttataaaga ttatggtgac tatatatcca aaatagttat
    29581 agaaggtcat acagatgatg tgggaagtta tatatacaac ttagatttat cgcaaagaag
    29641 agcatatagc gttgctaaat ttatagtggg agatgaaata ggtgactata aatacaaaga
    29701 taaagtgact aagcatatta ttgcaatagg aaggtcaaaa gctgaactca tcaaaaatgg
    29761 tgacaatagc gtgaatagag atgcatctag aagagtagaa ctaaaatacg aaataaatat
    29821 taatcaaaat aaataattaa atttttataa aaaaaaagaa ggcagttggt gtgagcttta
    29881 agccttcttt aaggaaaaag tttatttatt tttgttgata cttaacatat tatagttttt
    29941 agaagcagtt tgcaatatat taaacgtaaa tggtcgttta aaatgcataa ctggatacta
    30001 ctgatgtaaa atatttcatt ttatataata taaaaattat acagtgtcaa ttttctatat
    30061 tattgtacta taatctatta tttaaaatat tatgtaaaaa aatatcataa aaacgcatat
    30121 catgttataa ttactagagt attatgaata tggaggcgta gtttgtgata gaaataagta
    30181 taaaaaataa aaaaaattct aaaattaaaa ctttgatact tttattgata gtatctatat
    30241 cgatttattt aactggttgt actacatcag ataatggaaa taatcaatca aataataatg
    30301 attctttgtc tagtagtata tcaagtgata agaatgtaaa aattcatttt attgacactg
    30361 gaaatagtga tgcaatattg attcaagatg gtaaaacttt tacattgata gatgggggag
    30421 ataatgatga tgagggatta atggtagatt acctaaacaa tcaaggtgta aaagatatta
    30481 aatatcttat agctacccat tctcatgcag accatttagg tggacttgat tctgttgtca
    30541 aaaactttaa tatagaaaat gtttttgtat cgaatggttc agcagaaaca aagagttata
    30601 gggactttat aaatgcttta gcaaataagg gtttatcccc aagtgtaccg cttgaaaata
    30661 ataagttcta tttagaagat tcttattttg aagttctaaa tacaaatggg ggagatacta
    30721 ctaatgaaca atctctagtc cttgtatata ctaatgggaa tgataaagtt ttatttacag
    30781 gtgatgctga agaaggtacc gaaaaagaaa tactacctaa gcttgagaaa gtagaccttt
    30841 taaaagtagc tcatcatggt tctcgtagta gttcatctca agagttttta gataaagtaa
    30901 atcctgaata tgcggttctt ttagtaggca agggtaattc atatggtcat ccacatcagg
    30961 agacaatgaa taaattgaaa aaaatgggag taaaagtaca tagaagtgat gagtgttcag
    31021 atataatatt tgaatcaaca ggtgatggag tatttacaag ttgtaaagat ggaagttata
    31081 ataaaggtgt tagagaagat ggaaactctg gaaaatcaaa cagtaataca agtaaaaatg
    31141 attcttttaa aaataaacaa aatacattca attcagaaga aatagtgtat tttactccaa
    31201 aaggtaagag ttatcactct ataaaaaatt gtagtgggct ttcaagaagt aaaaaaatat
    31261 tatcaggcac aattgaagaa agtaagaaaa atgacccatg tgatatatgt tatggaaaat
    31321 aacaaaaaaa caaccaattt atctataaag cttctgaact ttaaatcatt taaaaaataa
    31381 aataaatgca taaaaaaaat aagctataat caatagataa tacatttcat ctatacgaat
    31441 agcttatttt tttaagtatt ttttaatagc tatttaataa ctctaaatac accagttaca
    31501 atacctacaa tttcaacttc tgagtcattg agcataattg gttccataaa atcattttct
    31561 ggctgaagtc ttattaaatt tccttcttta aaaaacctct taactgtagc agattcacca
    31621 tttataagtg caactactat ctgagaattt aaggccgtat tttttttgtc tactacaacg
    31681 taatcttcat ctaaaattcc tgcattaatc atactttcgc cttttactct taatacaaaa
    31741 ttgttactgc cctttactaa actggcaggg aatggaatgt attcctctat gttttgttga
    31801 gctaaaatgg gttctccagc tgttatttga cctactaaag gaagctctat tatttcttga
    31861 ttagctccag aaacatcatt tactttacta cgttctaaaa cttcaatagc tcttggttta
    31921 gtagggtcct ttcttatgta tcccagtttt tcaagtttat ttagatgaga gtgcacagtt
    31981 gaagtagatc ttaaccctac agcagtacat atttctctta cagcaggtgg ataacctttt
    32041 aatgtgattt gagactttat aaattccaat atcaagactt gcttttcagt tagatctaaa
    32101 tacataacat cactcatttc caaacatatt ttgtttttat ttccatacac tttatatttt
    32161 taattataac ataatccatt tatatctgca aacatttgtt cctgattttt aatcgtcctc
    32221 aatccattca aaattcttga ctatatcacg ttttacattt ttcttatgag ctgcataaag
    32281 ctgagtagtt gtgacattat catggtcaag taagttttga acatcatata tagaaaatcc
    32341 tgtttggatt agagaagttg cagccgttgc tcttaattta tggggactat atccattgtc
    32401 tctagtagta tcaagtggaa tagatgtata tttttttacc agtgttctta tagcctttgc
    32461 tgtaattctc ttattttgaa gagacaaaaa taaagcatct ttttcttcat catttaatag
    32521 ttcatctctt gttctttcgt tttgcaaata atcttttatt acatgttcac aagtatgatt
    32581 tataggcatt aaaacttctt tcccacgttt tctatatatt ttaaattcac ctcttgaaaa
    32641 attaaaagag gagatattga gttctctaag ctcatttaat ctaagcccgt atgtaacaaa
    32701 taatgctagt atagctttgt cacgtaattt agtttttctc caatatacct tttctttctc
    32761 tgtaagccct tcacctgttt ctactgattc aagcatctta gcaacttcat ctatctcaag
    32821 gcgcttaata gcatctggct gaggtttagg aagttttatt ggattgaatc catcagttat
    32881 attattatct atctgagagt ttctgtataa gaatttaaat agagtagaga tggatgattt
    32941 ttttcttgct aacgctctat tgttattttc aaaaatcaat gtgttttttt ctgtattttt
    33001 gtaatatcta ctgcaataat cacctaagaa taaatttata tctcttgatt ttattgtatt
    33061 aaaatcatct tctgtaatat cttttacaca atctgcattt gttaattctt tggtttcaat
    33121 caaatatgaa caaaaaaaat taatatcttc taaataagca agtcgtgtag aaactgcaac
    33181 agaacctttt aaatatataa aataatcctt cataaataca ggaagtttat tttccaaaag
    33241 tagacatttt tctatgagtt cattttcttt gataacaata ttatcaggtt tatctgattt
    33301 attatgtact tttataattt tcttatcatt attcaaaatt aaacctccta aaactaaaat
    33361 ataaatcttt tatattattt tttgatattt ataccaagtg agtataaata tttaatttaa
    33421 tcatttttta catttttaag agattagcag tgctttagat gaaattatca ctaactattc
    33481 cctaaatcca catttaaaga ctagttgaat ttaagtactc tttttttatt tctcaatata
    33541 tttatagaaa tattttaaaa tatattgaga aattttttat gctctactaa aatctttttt
    33601 atataatatt tttatatatt tctaacgaaa ccaaatatta gtaaaatatg tatttattta
    33661 actaaagttt ttaaatgggc tgactaagct taaaatatag gatattatga gagttactat
    33721 tgaaaaaata aaccctattg ccataaagaa acttataaat atgttatact taactattaa
    33781 actggatata ttcaagttat caaatccaaa taagtatgta attgaactta ttacaaaaat
    33841 aactataact ataaagctca gaccatttaa gctatttttt aaatcagcac tactaagtga
    33901 catatgtgta gatatagaat acattaaaaa cataaatata aaatacttca atgaatatac
    33961 actaggtgtt aacaacatta ttcttataaa attggaaata tcacctaaaa taatgtgtat
    34021 aaaaccattt atatttaaat tattaatcat acttacatat aactttaaat ctatattttg
    34081 agtcactttc atataactat ctggcagtaa tatcttaaaa attaaaataa tcattattgt
    34141 tccacctata ataggtgcaa ttcctataaa gaaatttcct atactttgat aaagattatc
    34201 ttttttatag ctatgactta catatcctag tataccatca tttttacttt ctattggtct
    34261 gaaaaactta actgaattta ttttatgcat gaaaatcaag cacattatca aatgactcaa
    34321 ttcatgaaca aacgttccta tagctccagt tacaataatt ccagtttttc caaaagatga
    34381 aaagataaat ttattattta gattttctgt aatgctaaaa atcaatccaa atacaataaa
    34441 tattcctatg aaacaaaaaa tatttattac acttattttt aaaatttcga ttatataaat
    34501 cataagttaa gtcctcatgt aaaagtattt aactactcta cttcatatcc attacagctt
    34561 aaaattttac aagcatcttc tatatctttt tcttttacta agatatagtc tgtatcatac
    34621 gtagaaattg caaatatgct tattttgttg tctgctaaca aactacttaa cttagataaa
    34681 attcctacaa gtgaaaagtc taaaggacct agtatcttaa gtattctcca ctccttttct
    34741 gacttaacat cagaaggaat attattattt aaacatacaa cacttaattc atcatcagtt
    34801 ctagttatag agtaaaactt ctctgtatct atccatgttg gtattttact gtcattattt
    34861 aatctacata ctgcatactc ttctaccaat aattttaatt tcataatgta tatttcctcc
    34921 aatcttattt gtttacttaa gattatacat taaaagttac ataaaataaa acatataaag
    34981 taaaaaaggt tcactatagt gtcctatttc tatagccaac ctttaaaact taattaaatt
    35041 ctaataaaga gatatattat ctaggttcaa ttataagttt aatggctgtt ttcttatcac
    35101 cttcgatttc tatatcagta aatgcgggaa tgcaaactaa atccattcca ctaggtgcaa
    35161 caaaacctct tgctattgca attgatttta tcgcttgatt tagagctcca gctcctatag
    35221 cttgtatttc tgcaacgcct cgttctctta gtactccagc caaggctcca gctacagaat
    35281 taggattaga ttttgatgaa acttttagta cctccatttc aacatctcct tgttaatttg
    35341 ttaaagtatc cattacctaa agtactaaat cataattgcc atttactaat tacaatcatc
    35401 atttaaagta tacttttata aaaatatact tctataatcg ttttaagaaa acctttattt
    35461 tttttaacca ttttattatg aaaaaactac aaatttcttt atattctata agcattttcc
    35521 aatatttcta aattttttat atctttgagc tataatttcc tctttatcca tatctttgta
    35581 atgatttaat ctttctaaaa tataagcttt tatttctttt gaaacagctt ctacatcttt
    35641 ttgtgctcct ccaagaggtt cttttataat cttatctatt atttttaaat catataaatc
    35701 attacttgta agcttcataa catcacaagc ttctttagct ttagatgaat ctttaaatag
    35761 aatactagaa agcccttctg gagaaatcac agaataaact gaatgttcta gcatacaaac
    35821 atcatttcct actccgatac ctaaagctcc tccactacca ccttcaccaa ttacaaaagt
    35881 gattactgga acagaaagtt tactcatttc aagtaagttt cttgcaatag cttctccttg
    35941 tcctctttct tctgcttcta aaccacaaaa agctcctgat gtatcaataa acgttattat
    36001 aggtctatta aatttttcag cttgtttcat aagtcttaat gcttttctgt atccttctgg
    36061 atgaggcatt ccaaaatttc tttttatatt ttcttttgta tctcttcctt tttggtgtcc
    36121 aactatagta acattaaact ttcctatctg accaatccct ccaaccatag aagggtcatc
    36181 tttaaaaagc ctatctccat gaagttctaa aaaattagaa caaatatgtt ctatgtattc
    36241 caatgtcgta ggtctcttta tatctctact tagtgttacc ttttcatatg ctgatagatg
    36301 tgaaaaagca tcttccttaa gcttttccaa tttctcatta agtgaattta ttttatcact
    36361 taaatctata ttatttgcct tagaaatagt tattaattgt ttaatatcat tttctaagac
    36421 ttttattttt tcactattat tttcaatcaa aacagttcct cctttatgcc ctatttcttg
    36481 tgcatagcaa gaatttgata taataattcc ttcatttttc ttctatctac tatcatgtca
    36541 ataaaacctt tttcaagtaa aaactcagaa gtttgaaatc cttcaggaag tttttgattt
    36601 attgtttgct ctattactct tggacctgca aaacctatca acgtatttgg ctcagaaatt
    36661 ataatatcac caagcatagc aaaactagca gttactcctc cagtagtagg gtcagttaga
    36721 actgatatat atggcaatga tttttcttca agcttagaaa gtgcttgaga agtctttgcc
    36781 atctgcataa gagataccat accttcttgc attctagctc ctcctgaagc agaacaaata
    36841 attataggta aattattttc agcagcatac tctattgaat aagttatttt ttccccaaca
    36901 atagaaccca tacttcccat cataaaatca ggattcatta cacaaataac tgttttaatt
    36961 ccatttattc ttccataacc tgtgacaaca gcttctgact cttttgtttt ttccttataa
    37021 gagtctactt tttctttgta tttaggaaaa tttagtggat tttgaaattc tacatcagaa
    37081 ttaaactcca taaaagttcc tttatcaatc aataaattta ttctttttct tgctcttaag
    37141 ccataatgtc ttgaacattt tggacataca aatgaatttt cttctatgtc ctttctaaat
    37201 acatgactat cacaaccttt gcaataggtc caaaatttat catctacact attcttttta
    37261 aagttgtcat ctaaagaaat cgtaacatac ttagattctt ttgatgataa aaattttttt
    37321 atcataatct atttactcct tataatgtag caaattcttt cttcataaag acatcttcta
    37381 taaatttggt atgatgagta tcttctctaa actcctcact tgttacaagt gccttttgaa
    37441 attctacatt tgtattaata ccttctacaa taatttcgtc tagagctcta tatattctac
    37501 ttatacattc ttctctagtt tcagcccaac atattaactt acctatcata gaatcatata
    37561 aaggtggtat agtatatcct gcatatacaa aagtatcaaa tctaacacca aaacctccag
    37621 gtaaatttaa tgattctatc ttacctggtg atggagcaaa attctttgat gaatcttctg
    37681 catttattct acattcaata gcatgacctc taaaagtaat atcttcttgt ttaaaaggaa
    37741 ttttatcccc attagctata gatatttgaa gttttataag gtcaagattt gttaccatct
    37801 ctgtaactgg atgttcaact tgtattcttg tattcatctc tataaaataa aagtttttat
    37861 ctttgtcaac tataaactca atagtacctg caccgatata acctactcct tttactatat
    37921 ctactgcaat tttatgaagt ttttgtcttt cttcatctga aaggtatgga cttaaagatt
    37981 cttctattac tttttgattt cgcctttgca tagaacaatc tctatcacct aaatgtattg
    38041 catttgaatg tttatctcca aatacttgta cttctatatg tctaggattt tctataaact
    38101 tttccatata taaatcacta ttagaaaatg ctgctagagc ttctgaactt gccatatcaa
    38161 aatttgaaaa aagttcttct tcttttctaa cgattctcat accttttcca ccgcctccac
    38221 ttgaggcttt tatcataaca ggatatccaa tttctcttgc aacttctaaa gcttcttcct
    38281 tagttttcaa aacagattct gaaccaggaa caacagggat attcaattcc atcatagttt
    38341 ctcttgctct agatttatct cccatcaaaa tcatttgttc tcttgttgga cctataaaaa
    38401 taatattatt atcttcacat tgctttgcaa attcaggatt ctctgataag aatccaaagc
    38461 ctggatgaat agcatcacac tttaatttaa gagcaagata gattatattt tctatattat
    38521 tataactctt acttatatta tttggtccta tacaaataga ttcatcagct atatatctat
    38581 gaaaacaatc tttatctatt tcagaataga tagcaacagt ttttatacct agttctttac
    38641 atgttctgat gattctaact gctatatcgc ctctatttgc aactagtatt ttttttatca
    38701 acttaaatac ctcctactac aatggtttta tcttaaataa aggttgatta tattctacta
    38761 gttcttcatt actaactaat acttcaatta tttcaccttt aatttcgctt gttatctcat
    38821 tcataagctt cattgcttct aatatacata aagtgtcgcc ttcttcaact acatcgccaa
    38881 ctttaacaaa gctatctgca tctggacttg gagaatcata gaatgttccc atcaaaggag
    38941 ctactactac tgatagattc tcattagatg tgacaggtgt atcgtttaca actggctttt
    39001 ctaaagaaag atccactact gattcttgtt gtacacttaa aacaggtgaa cttgtagatt
    39061 gagctttttt agatacttct aatcttaaat cgctactttc aagttttaca tattctaagt
    39121 tagttgagtc tatggccttt aataattcct taatttcatt gatgttcatt ttgttacccc
    39181 cttgtattat tacctggtgc taatattata tcacaaaaaa caaatttata aaagaaaaag
    39241 tgctgactag agaatcaaca catcaatata tcttttaatt ttaaattaac aaccagtaac
    39301 ttatatttgt tttaattttc cattattaat ataaattata agtataaaat gaataaaatt
    39361 caatattttt tgcaaaatac aagagaatac aaattaatac ctcgggaatt tttaagacaa
    39421 ataccaatat tatgcaattt agacttcgct ttctttcaaa ttagtatcat tttctttatt
    39481 tttacatagg atgtacttta atttagctat caaaacatta ctatataggt taaaagttat
    39541 tagaattgca ggaattataa agtaaactct agcacctata aaaccaaaaa ctactgtaat
    39601 aagtattaat cttttattta aagtaaaaaa aggtatatta aaaatacttt tgtcggatgt
    39661 ttctggagta taagaatata taactccaaa aatcaaagta agcatacaaa gtggaagtag
    39721 tgtataactt gaaattattc ccagaaatcc tatactttca aaatatttgc tagcactatt
    39781 tgtataaaca aacatgtatc catttaaata tgcgcatata catgatataa tgccaaaagt
    39841 tccccctaag gattgagtgt accaattaaa aaatttagat tccatatacc tcacctccta
    39901 aaactgtata tataatgata tgcatttaaa tagtaaaata tatctttata tgtttctgaa
    39961 taaaattttg ttaatttcat taatttatgt ttaagaaatt tgaagtatag tgtagtatat
    40021 attaatgtag atgaagtttt atagtactta tttcatagtg cttaatcaag ttatcttatt
    40081 atggattcaa aagttgtttg tagggtttta tattttgttg agctgaaaaa tttattataa
    40141 atgaagggat gttttcgctt tggtagatac attagaattt ggtcttaaaa ttttattttt
    40201 tatattatca ataatttgga tgggtaaaat aatgatttta agaactgata agcaaatagt
    40261 aatcaatcct ttgcttattg gtatatctgc agtccttgtg atgttgcata cctcacagag
    40321 taacattgaa ttttttggat tagatgtcca atatataaga atagttttgt atataatata
    40381 ttcactgata attttaatag gaatatgggc tactaacaga agaaatggaa ttttttagat
    40441 aatctatttc tataaaattt aaaggttgct agtaacaaag cactaatatt agcgttctgt
    40501 tactaacaac ctttattttg attatacact taaattgaaa atagaatgat tgaataagtt
    40561 gacatattat tttacattga cagtgattag aacttcttga gatgtattta aatcattttt
    40621 gtcgcttagt ataactttta ccacagcttg acctgtttta ttacctttaa ttatcatatc
    40681 ttcacatgaa agtacactct tatcacttac agatacaata aagtctaaat cttttggaag
    40741 attatcagta acttcccagt atttataata actatcaatt ttcttcgtaa ttatttttct
    40801 caaatcaata ctttcacctt ttgctatatc aacattatga tatttagagt ccagtttata
    40861 ctgattatct tttgtatcaa taaaatttaa atcgcaattt acatccacac cattatgaga
    40921 aagagaattt actacatcgt catcaatcaa ataattattg gcaagattta ttgaatccat
    40981 atcttttaga cttaaagctt ccttaggaac ctcttttata ttattattcc aaaaaataaa
    41041 attgtctaca ttttcaagat atgatattcc ttttaaattt gaaatgctct caccagttgc
    41101 ataaaattct ccatctaaag cctttatatt gcttatagtc atctcatctg ggtttatata
    41161 tctttttaca actgctctta aatttgcatc aggaaaaata tctttaagtt gattttcgct
    41221 caaaacctta tcatttgaat ttattggact taaagctgct gcagaaataa taaatggtat
    41281 taaattagct aaattcatag taccctccca cataaatttt ttattataat aatttaattt
    41341 ctatgagagg gttctgtttc cttgttatat atacctactt tcgtacactt tattaatata
    41401 aattaaaata aatttctact attaaactta taaacatatt actagttacg ttttttagct
    41461 tcacatctaa atattcgcat accttgtgac ataaatttgt cttcatactc tgttgtaaca
    41521 ttattttcat actcactatt tcctaaatca agagaaatat tctttaatag ccaattattt
    41581 gcagcaattt catttaaact aaactcgaat aatttttcat tatctgtttt aaagtgaatt
    41641 tcgccatcat cttccaaaac cctattgtac atttctaaaa atccagaatg agtgagtctt
    41701 cttttactcc atctattttt aggccatggg tcacagaaat ttatataaat tctcgataat
    41761 tctttagctt caaagtaatc caaaatattg cttacatctc cccataaaaa tagtatatta
    41821 ttcaaattag aagcatctgc tttttcaaca gcttttaaaa gaacttcttc cttaagttcc
    41881 atggcaatat aatttatgtc agggttctgc ttagctaaag ttgttataaa cttacctttt
    41941 ccagtcccaa attcaacatg tattggatta tcatttctaa actttaaatt ccacttgcct
    42001 tttaatttgt ctatatcgtc tcttaaaaca tattttgtat aacttaaaag cttttcatct
    42061 gcaccttttt ttcgtcttct tctcacaata attctcctta catataaaaa attagtaaaa
    42121 tacattttta ttatacatta tctcaccaaa aaataaaaag aactctctta aaatagaaat
    42181 ttatttctat aaagagagtt ctaaacttac taaaaactta atcttagtgg caccctgaac
    42241 aaccagagca tcctcctcca ccttgatctt tcatattttc aggaataact ctaaatccaa
    42301 atcctgtatc ttctattatt atatctccat actgactata ttcatcagag ctcattacaa
    42361 attgtaattc tccaacttca taagttaagt catcttcttt tttctcatct aaagctaatc
    42421 caaaagaagg acctccacaa ccaacacctg caaagtatac tcttatatta ttaggtttat
    42481 cttgattgtc ttttaagata ctttttaaag tatcaatagc tgtttctggt aaagtaattt
    42541 tcatcaaatc attccctttc aaatatttta ttaaaacaat atctattata tacccataca
    42601 aggtacataa tcaattagtt tttgcatatt ttactaaaac ttctacctaa tattacctaa
    42661 ggctttaaaa tattttatat aatattttat taccttaaat aaatacccta
//
LOCUS       DAMJYN010000031        42147 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.032, whole genome shotgun sequence.
ACCESSION   DAMJYN010000031 DAMJYN010000000
VERSION     DAMJYN010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 42147)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42147)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42147
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.032"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            27..695
                     /locus_tag="PC466_001734"
     CDS             27..695
                     /locus_tag="PC466_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YwaF family protein"
                     /protein_id="HDF2769121.1"
                     /translation="MFKIFLFSSEQFVSLFIFGLFLYYCPKLTKNILPYSYTVEKIIC
                     TLLVIIMALEQLLLISSGNYSTLNSLPIGINYICIYLCIAILIFKQYHLFNIFFSWSL
                     VCSVGELIFSKNLGYEFPSLIYFIFIFSKCLIIYADIYMVDVRKFRVNRYALRDNLAI
                     CFIYFSFIFLLNTFTNSQYYYGFLSHSTTAIFTFIFVTSIMYIPALLFNRDTFILEKK
                     KKSK"
     gene            complement(786..2237)
                     /locus_tag="PC466_001735"
     CDS             complement(786..2237)
                     /locus_tag="PC466_001735"
                     /EC_number="3.4.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucyl aminopeptidase"
                     /protein_id="HDF2769122.1"
                     /translation="MNIKYSKEILKSLENAITVVALFEGEDVSTTFDKINMISRNFNS
                     KENSIDTVTLVENNNLVNVCLVGFGKRELLNREKIRIIGGNLCKKLKNILKNEAYKSS
                     DVNVLNLNLNSDEIGSFVEGILLGNYKFDKYKTKSKDFERKEVDTITIFTEKEVECQI
                     EKAKILANSTIIARNLVNEPSNVIYPKTLAIETVKLGAEFGFNVDVYEEEKIKALGMD
                     AFFAVSRGSINKPRFIVMRYFGDKESTDILGLVGKGLTYDTGGYSLKSNASMLDMKTD
                     MAGAASVIGAMCAISQSKLKKNVIAVVAACENALSGGSYKPGDIISSMAKKTIEVLNT
                     DAEGRLTLADAIYYIINNEKVTKVVDVATLTGAALTLLGNVATPIVTNNDDFYCELEK
                     AATLSGERVWKMPIYDEFKDMIKGEEADLKNTGGKNAGCITAGAFIGEFVGNTPWIHM
                     DIAGTSTSSKSIGYKAKGATGEPVRTLYYLAEI"
     gene            complement(2253..2693)
                     /locus_tag="PC466_001736"
     CDS             complement(2253..2693)
                     /locus_tag="PC466_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF2769123.1"
                     /translation="MSDKELSILLLESMNNFHNLIKIINNERYKKDKVLTERQFFALV
                     KIRKHDKIELKNLSRDLHVSTSSLCILLNKLVEQEYVYREEDSRDRRNTFYGITKNGE
                     KILDNEILKFVSIISDKMDCLDIDNKDKLFTSLEESKNIIEQLF"
     gene            complement(2941..3369)
                     /gene="ytfJ"
                     /locus_tag="PC466_001737"
     CDS             complement(2941..3369)
                     /gene="ytfJ"
                     /locus_tag="PC466_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GerW family sporulation protein"
                     /protein_id="HDF2769124.1"
                     /translation="MRATGSIQSLMETTLETIKGSIDANTIIGDPIKTDTTVVVPISK
                     VTIGFGIGGGEYSKGYDDKDREIELKNEKSDTNFAGGSAGAISVQPVAFVVVESGETR
                     IMSLDSNINLVDNILSITPRVLEKIQNISQSNKNQDKNNM"
     gene            complement(3323..3952)
                     /locus_tag="PC466_001738"
     CDS             complement(3323..3952)
                     /locus_tag="PC466_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2953 domain-containing protein"
                     /protein_id="HDF2769125.1"
                     /translation="MELNELFNFKYLIIAVIFIISVTMLILISHINILIIADINNKDI
                     CLKLNIKYMFNLININRQLYPAENSKNNDKKEGMKNNIDSSILLADDLLSIYRLLKKI
                     KIHELYSNINFGTGNIGLTSSVYVLINTLYGNLFNMIDAEKMYLNVNPDFTKDYVLGN
                     IRIHIRPRIKALFNIIIMINKIMNKNKGNKEGDSNESNRFDTKSYGNNS"
     gene            complement(4114..4653)
                     /gene="scpB"
                     /locus_tag="PC466_001739"
     CDS             complement(4114..4653)
                     /gene="scpB"
                     /locus_tag="PC466_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HDF2769126.1"
                     /translation="MKREDIKYIIESVMFAYGEPISIKELNYIINKELSSKEIEIMLN
                     LLIEEYREQNRGIQIIKLENKYQMCTNKDYAEYIKKIIEPKKKKSLSQATLETLTIIA
                     YKQPITKVEIEDIRGVKCDKVLQTLFENELIREAGRLNKIGKPIIYKTTDEFLKLLNI
                     ESLEELPPIENYQEVATNE"
     gene            complement(4655..5374)
                     /locus_tag="PC466_001740"
     CDS             complement(4655..5374)
                     /locus_tag="PC466_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HDF2769127.1"
                     /translation="MKYNIQLQVYEGPLDLLYDLITKHKIDIKDISIIDITKQYLNYL
                     KMLDKMDLEITSEFITMASKLLEIKSKYLLYKQKDEEEDPRIELMEKLEEYRKFKVAS
                     QDIKENITYVNERFYRNKEEIIIDDNVDLEDISIEAIKNILPYIFKVKTSQIENANDE
                     KLDKIVRKKIISVEEKILYIRDIIKDKIEVTFTNIIKSYENDEIIATFLSILELIKEK
                     EIVVVQDIFFDDILIRKSSEC"
     gene            complement(5404..6000)
                     /locus_tag="PC466_001741"
     CDS             complement(5404..6000)
                     /locus_tag="PC466_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HDF2769128.1"
                     /translation="MLSMNIGEIVASLVGIAMAISIHEFGHAYSAHLLGDDTAKAYGR
                     MTLNPVRHVDPIGLLAMFILKIGWAKPVPVNPNNFKNYKIGNLIVSLAGVFCNVLTAI
                     LCVIINKYVHMYAINTIAGYVLIYSMGFAAFNLLPIPPLDGWGVISTFVPYKWNEYLY
                     KFESMSYIILLIALFTGIYQIILSPIYTVLLKIVYLFV"
     gene            6298..7134
                     /locus_tag="PC466_001742"
     CDS             6298..7134
                     /locus_tag="PC466_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDF2769129.1"
                     /translation="MRQEERTVCFDRELKIEAYRFKGIMQKFPNHFHEHYVIGFIEKG
                     QRYLSCKNKEYTTSTGDLLLFNPFDSHTCEQIDDKVLDYRCINIKPEIMKKTVFEITG
                     KNYLPKFNQPVIFRSELVPLLQELHYIIMEEELDFKKEELFFFLIEQLIEEHTEPNLQ
                     SNLENTNIEIQAVCDYLENNYAEHIVLDELSTIAGMNKYSLLRNFTKLKGITPYRYLE
                     NIRVNKAKKLLEKGVEPIDAAIQTGFVDQSHFTNFFKNFIGLTPKQYQNIFINDDSNN
                     FK"
     gene            7155..7577
                     /locus_tag="PC466_001743"
     CDS             7155..7577
                     /locus_tag="PC466_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2000 domain-containing protein"
                     /protein_id="HDF2769130.1"
                     /translation="MENKNSKCVMVIDENLPMGIISNTAAIMGITLGKHAPETVGPDV
                     IDKTGNSHLGIIDIPVPILKGNKEIIKDLRKKLYTLEFNDLTVVDFSDVAQSCNLYEE
                     FTQKIASVPEDELQYFGIAIYGNKKKVNKLTGSMPLLR"
     gene            complement(7788..8951)
                     /locus_tag="PC466_001744"
     CDS             complement(7788..8951)
                     /locus_tag="PC466_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HDF2769131.1"
                     /translation="MKKLASTALAILIALTPLSFSFANNKENADANQLNISSKSAILM
                     DVGSGQILYEKDAHKKLPPASVTKVMTMLLIVEALDSGKIKLDDEVQVSETASSMGGS
                     QIFLEPGETQKVDTLLKGIAVASANDACVAMAEHLAGSVEGFVDRMNAKAKELNMNDT
                     HFANTNGLPVANHYTSAHDIALMSRELLKHEMISKYLTTWMDKVVVGKKQVTVGLANT
                     NKLIKHYQGATGVKTGFTQEAKYCLSASAKRGNTHLVAATLGAETSPERFNDASSLLN
                     YGFANYESVKLCSKGDNIATLTLDKADENKVKLVAKEDLNALIKKGSSKEFEKKIEIV
                     KNPKMPIKKGTVLGKIKICKDKKVIGEVELINTKDINKASYLQMLQRIIDNMI"
     gene            complement(9005..9205)
                     /locus_tag="PC466_001745"
     CDS             complement(9005..9205)
                     /locus_tag="PC466_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore protein"
                     /protein_id="HDF2769132.1"
                     /translation="MDDVSRQNAIKALKQTKMEIAGEYGMNYEDAFEIIENASNKGVL
                     EGYFKKLEKKKNLGQGISRHLE"
     gene            complement(9411..11087)
                     /locus_tag="PC466_001746"
     CDS             complement(9411..11087)
                     /locus_tag="PC466_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HDF2769133.1"
                     /translation="MQLFKKNTNKIKVMALGGLNEVGKNMTVVEYKDEIIVIDAGLSF
                     PEDEMLGVDIVIPDITYLVKNRDKIKGIFITHGHEDHIGALPYILKKINVPVYGARLS
                     IGLIQVKLKEHKMNNVKLNVIGPRQVIKLDNMEVEFLKNNHSIPDAYSIAIHTDQGII
                     YHTGDFKIDLTPIDGDVMDMHRICELSKKGVLLMLADSTNAEKPGFTMSEKTVGVGLD
                     ELFAKGNGRRIIVATFASNIHRLQQIINTAEKFNRKVAISGRSMVNVVGVAKELGYLD
                     ISDDMLIDLNDICKYEDSELVIITTGSQGEPMSALARMAFSEHKKVEIKSGDLVIISA
                     HPIPGNEKLISRVINFLFEKGAEVVYSDIADIHVSGHACQEELKLIHALVRPKFFMPA
                     HGEYRMLKRHAEIAEQLGMDKENIFVMQTGDVLELDKNSAKVANRIQTGNILVDGLGV
                     GDVGNIVLRDRKHLSEDGLMIVVVTISKDEGKVLAGPDIISRGFVYVRESEDLMDGAK
                     DIIKNVLNECEEKNIKEWAYLKNNIKENLKEYLYQKTKRNPMILPIIMEV"
     gene            11304..12041
                     /locus_tag="PC466_001747"
     CDS             11304..12041
                     /locus_tag="PC466_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HDF2769134.1"
                     /translation="MRGKTHCAIGILTAIQTSLIFKIPISLVDILVSATFAVLPDLDK
                     SNSMVSNFILKNNVSKYIYRIFIYAVNIIIFFISININDNFYLSAIITFVAIIIIEAK
                     LTHTFLRKVFLSLIFILLAICLYIIEVEIYFTIFCLMLSIFPWLKHRSFSHSIFATII
                     VYFLLKQIELITNINNLSFYGTIGYASHMFLGDLFTKQGIPIFYPLSEKKISLGFLTV
                     GGPFSNFIEKSFIFVLIGLIIFSILKL"
     gene            complement(12158..12616)
                     /locus_tag="PC466_001748"
     CDS             complement(12158..12616)
                     /locus_tag="PC466_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HDF2769135.1"
                     /translation="MANTMDLLKDKLKETGFKITPQRRAIVEILLKHDHSHLSSEEIY
                     DLVRVDCPEIGLATVYRTMQLLDEIGLISKLNLDDGCIRYEISLHKEDCHNHHHLICK
                     NCGKIMEAKEDLLDNIEKEIQSLYKFKILDHDVKFYGLCDECNGVSDSEE"
     gene            complement(12898..13185)
                     /locus_tag="PC466_001749"
     CDS             complement(12898..13185)
                     /locus_tag="PC466_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HDF2769136.1"
                     /translation="MEENIINLIDENGVESQFEIILTLEAEGKEYAILMPLDDEEAEE
                     ALIFRIDEDEEGEILIPLESDEEYETVVAVYTAIMEEEGLNYDEDESNGLN"
     gene            complement(13263..13688)
                     /gene="ruvX"
                     /locus_tag="PC466_001750"
     CDS             complement(13263..13688)
                     /gene="ruvX"
                     /locus_tag="PC466_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HDF2769137.1"
                     /translation="MLDGRIMGLDVGDKTIGVAVSDLMGLTAQGVKTIKRVGKKKDIE
                     ELKAIIKEKQVNKIVSGLPKNMNGTLGPQGEKVIKFCELVKAETGIDVEFWDERLSTV
                     AAERSLLEADVSRQKRKKVIDMLAAVIILQGYLDFKINS"
     gene            complement(13894..16065)
                     /locus_tag="PC466_001751"
     CDS             complement(13894..16065)
                     /locus_tag="PC466_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769138.1"
                     /translation="MRKKIMSLFAIVIMIFVSTASYGFAEEKGKVIFIDMNRTNLGSM
                     MNIPILKNEIEKRGYVALMNIRGDQGTDDRRSYASMGAGTRASVTTEDYINFQKVDQD
                     TAKAFEVATGQKAKEINDLGINRSINENLEYGEYGANLGSLGKTLSENGLKTSVIGNA
                     DIIENNQLVKNRNLCLVAMDQYGRIDSGNIDNINKKDSKMPFGISTDYDKLLDETKKS
                     YKNSDAIFVELGDTYRLDMYRLNLNDNTYGTMKKNIVKNINKYLEQVFSMVGENDTVY
                     IASAFPSDLDYKNKRRLSPIIKFSGEGKGLLESATTRKAGIVANLDVGVDILGTFGLE
                     NKEMVGRSYTLVNKEDNVGYLKSLYERIVSISSIRSTIINGFVGVISASWVIAMFAIF
                     FRNYMPHKERVFKVLKEFIKLGIIMPLSFMLAPLMNFKTPISISLGIFATTLILYLLG
                     RKLFKDNDIKHMGFFATLTILVIVIDSVFGTYLMQNNIMSYDAVIGARYYGVGNEYEG
                     VTIASAVFGLAVLLHYKKVSKLLVVIFSLIILITSAYPSMGANVGGAISECVAYLLFI
                     MLIYDIKIDFKKAVLLAVSAVVVVFAFAALDILSGSESHLGMFVQRIFLNGPGEILQT
                     FGRKIQMNMQLAQTSVWVNILLVGIGVIAVLIFKPSRHFRKIMNNFPILFKGFIASMV
                     GCIITLLVNDSGIVAASTASIYILIPLIIININMIIFEKNN"
     gene            complement(16075..16332)
                     /locus_tag="PC466_001752"
     CDS             complement(16075..16332)
                     /locus_tag="PC466_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HDF2769139.1"
                     /translation="MEKDLDYTMKFEGIPEDRMSVGDTIDFVYKALVEKGYNPINQII
                     GYLLSGDSSYITSHKNARAIIKKFERDEILEEVITHYLNRK"
     gene            complement(16357..18996)
                     /gene="alaS"
                     /locus_tag="PC466_001753"
     CDS             complement(16357..18996)
                     /gene="alaS"
                     /locus_tag="PC466_001753"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HDF2769140.1"
                     /translation="MEKMGLNEIRSKFLEFFESKGHYVANSYSLVPNNDKSLLLINSG
                     MAPLKNYFSGVEVPPSVRMCTSQKCIRTGDIENVGITARHATFFEMMGNFSFGDYFKR
                     ESIKWGWEFVTEWLNIPEDKIWVTVYEEDDDSYDIWAKEMNFPEERMVRLGKDDNFWE
                     IGTGPCGPCSEIYFDRGEEYGCDNPDCKPGCDCDRYLEFWNHVFTQFDRDEEGNYSLL
                     ENKNIDTGMGLERMGCIMQGVDTIFEVDTIKSILEAVEKLTGVKYGENPKNDISIRII
                     TDHIRAVTFLVSDGVLPSNEGRGYVLRRLLRRAARHGKLLGVKELFLQKLIDEVIKVN
                     DKAYPVLVEKESYIKKVVGIEEEKFNETIDQGTEILNSYIEVLKNEGKTVLSGQEAFK
                     LYDTYGFPIDLTKEILEEEHLSVDEEAFNEEMEKQKERARNARGNMDGESWKEDPLSK
                     LESTVDSTFNGYSEIYGEGTIEAIVKDDELVQSAEEGDKVSIVLDNTTFYPEGGGQVG
                     DCGLITNENLVLEVLNTKKGANNSIKHIGIIKSGRISNGDKVKTLVDRETRMSAARNH
                     SATHLLHKALREVLGEHVNQAGSLVTPERLRFDITHFEAISNEELKVIEEKVNNVILS
                     SLDIKCDIMNIKEAKEKGATALFGEKYGDEVRVVSMGDYSTELCGGTHLTNTSQVGMF
                     KILSEGGVAAGVRRIEAITGKAVYEYLKERDGIISEVCVNLKSKEDNLIQRISSLLEE
                     NKNLSKELHDMKAKMSLQSVDSIFDSKVEVNGVNLITNKFEGMDMDTLRETADNLRDK
                     LGSGVVVLANVVDDKVNFVVTATKDVLDKGIHSGNIVREVAKIAGGKGGGRPNMAQAG
                     ASDVSKVDQALSYASEVIKTQVK"
     misc_binding    complement(19064..19302)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(19445..20524)
                     /gene="mnmA"
                     /locus_tag="PC466_001754"
     CDS             complement(19445..20524)
                     /gene="mnmA"
                     /locus_tag="PC466_001754"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HDF2769141.1"
                     /translation="MNKKVMIGMSGGVDSSVAAYLLKQQGYDVIGVTMKLWQDDDVVE
                     IEGGCCSLSAVEDARRVANKIGIPFYVLNFREVFKEKVIDYFIDEYLEGKTPNPCIAC
                     NKHIKFDDFYKKARQIGCDYVATGHYAKIEKDESTGRYLLKKSVTDKKDQTYALYNLT
                     QEQLEHTLLPIGDYEKDRVREIAKEMGMAVHNKPDSQEICFVKDNDYANYVKKHSKKR
                     IEEGFFVDTKGNILGKHKGILYYTIGQRKGLGITFGKPMFVIDINPINNTIVLGDNED
                     LFKKELIAKDVNFISIDTLEEPLRVQAKIRYSAKPSPATIHRVGEDTIKIVFDEAQRA
                     ITKGQSVVMYDGDIVVGGGIIEKSL"
     gene            complement(20813..21253)
                     /gene="nifU"
                     /locus_tag="PC466_001755"
     CDS             complement(20813..21253)
                     /gene="nifU"
                     /locus_tag="PC466_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly scaffold protein NifU"
                     /protein_id="HDF2769142.1"
                     /translation="MQYSDKVMEHFMNPRNMGEIDNASGVGEVGNPTCGDIMKIFLDI
                     DGDVIKDVKFKTFGCGSAIASSSMATEMIKGKTIKDALELTNKAVAEALDGLPPVKMH
                     CSVLAEQAVKAALIDYAQKNNIHIPELDGYVIDDAHDHDVEEEE"
     gene            complement(21307..22500)
                     /gene="nifS"
                     /locus_tag="PC466_001756"
     CDS             complement(21307..22500)
                     /gene="nifS"
                     /locus_tag="PC466_001756"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase NifS"
                     /protein_id="HDF2769143.1"
                     /translation="MEKRRLYMDYSATTPIKKEVLDAMMPYLTDYFGNASSFHTFGRE
                     AKDALDKAREQVAALINAEPSEIYFTAGGSESDNWTLEGVAYANKNKGNHIITSKIEH
                     HAILHTCEYLAKHHGFEITYLDVDSEGRVDLRQLEDSIKDTTILISIMFANNEIGTIQ
                     PIKEISEIAKKHKILFHTDAVQATGNIPVDVKELGIDLMSMSSHKIYGPKGVGALYIR
                     KGVRLHNFVHGGAQEKSKRAGTENIPAIVGYGKAAELAKENMQNHVETLTRLRNKLID
                     GVLERIPYTRVNGSLENRLPGNANFAFQFIEGEGILLLLDMLGIAGSSGSACTSGSLD
                     PSHVLLAIGLPHEIAHGSLRLTVGDFTTDDDIDYILENLPKVIERLRSMSPLYDDAKK
                     QGLVK"
     gene            complement(22518..22964)
                     /locus_tag="PC466_001757"
     CDS             complement(22518..22964)
                     /locus_tag="PC466_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HDF2769144.1"
                     /translation="MKLSTKGRYGLKAMFELALNQDNGPVSLKFIAKKQKISDQYLEQ
                     IFSSLKKSGLVKSVRGAQGGYLLSKNAEDITVGDILVVLEGPVALSDCVLDEDVCENS
                     NMCVTKIVWEKMKKGIEDVIDSITLKDMINDYNKNKLENDITNIKK"
     gene            complement(23073..23843)
                     /locus_tag="PC466_001758"
     CDS             complement(23073..23843)
                     /locus_tag="PC466_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2769145.1"
                     /translation="MIIKLNSTYHSRVMKYLKKEPEYNLFIIGDIERYGYGNNFLNIW
                     ADVGEHGEIKAILLKYFEFMMFYSDGEYDVEGFYNLLRNTNYEEISGKICAVDTLAKR
                     LGLNNLKVVDFCKLQTKKFLIDNNCNAKVKRIRLGNLKKTVKLYDLIDEFHSTTLENL
                     KNGLRTGRGYCIEINKQVVSMAKSTSENRTHAMIIGVGTHPKYRAKGLATKCLIKLCS
                     ELLRENKIPCLFYDNEEAGKIYKKLGFENIGKWGIYSK"
     gene            complement(23874..25139)
                     /locus_tag="PC466_001759"
     CDS             complement(23874..25139)
                     /locus_tag="PC466_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HDF2769146.1"
                     /translation="MPLADKIRPKTMNDVIGQSHIIGNGKILSKILQSNFLPNMIFFG
                     PPGVGKTTVAEIIAERSNKSFYKINATNSSLEDIKKVISELGSINNVNGVLLYIDEIQ
                     SFNKKQQQSILEFMENGSITLIASTTENPYHYVYKALLSRSTVFEFKPLEKLDIEKGL
                     KRAVEVLNEDSYMDIECNNNAIEDIAILSDGDMRRALNILEVVVYSTKPNKDNITYID
                     SDVIRASTFNKIINYDKNGDSHYDILSAFQKSIRGSDPQASIHYLARLIKGGDLISIC
                     RRLLVIASEDIGLAYPNAIVIVKACVDSAMQLGFPEAKIPLAEATILLATSPKSNSAC
                     IAIMKAMDELDKEFVKDIPNSIKDAHYSGSKEIGRGCGYKYPHNFKNHYVKQQYLPDS
                     IKDSIYYIPQENKTEKNIKKYLEYLNSDF"
     gene            complement(25246..26031)
                     /gene="codY"
                     /locus_tag="PC466_001760"
     CDS             complement(25246..26031)
                     /gene="codY"
                     /locus_tag="PC466_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HDF2769147.1"
                     /translation="MASEVLQKTRKINKTLQTSGGSSVSFDLLAGALGDVLSSNVYVV
                     SAKGKVLGLHLNDVQDSSVIEDEYTKQKKFSDEYTQNVLKIDETLENLNGEKILEIFP
                     EEHGRLQKYTTVVPILGSGQRLGTLVLSRYSNSFNDDDLVIAEYSATVVGLEILRAIG
                     EELEEEMRKKAVVQMAIGTLSYSELEAVEHIFAELDGKEGLLVASKIADRVGITRSVI
                     VNALRKFESAGVIESRSLGMKGTHIRILNDKLTDELKKLKNNQ"
     gene            complement(26196..28283)
                     /gene="topA"
                     /locus_tag="PC466_001761"
     CDS             complement(26196..28283)
                     /gene="topA"
                     /locus_tag="PC466_001761"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HDF2769148.1"
                     /translation="MAKTLVIVESPAKAKTIEKFLGKSHYTVKASVGHVRDLPKSKLG
                     VDIENNFEPQYINIRGKGDVIKELKKEAKKSKQVYLATDPDREGEAISWHLAHILNLD
                     ESEDCRIEFNEITKDAIKKAIKHPRNIDINLVDAQQARRVLDRLLGYQISPILWQKVR
                     KGLSAGRVQSVTTKLICDREKEIKAFIPKEYWTIDVEAKTVKDKDITLKFYGKNDEKI
                     ELENEEAVNEILKEMEGKDLKVEKIESKSRRKSAPKPFTTSMLQQEGANKLFFTTKKT
                     MMIAQELYEGIDIEGEGTVGLISYIRTDSKRISDEAKEKAKGYIVNNLGENYYKNTGD
                     KKEKKDTKKVQDAHEAIRPTSVDRTPESIKASLSKDQYKLYNLIWRRFVASQMEDSVF
                     DILNVECKIGDIVFKATGSKMKFDGYTKVYNFSEREDKILPSIEKGDILNIENILPDQ
                     HFTQPPARYTEASLVKTLEELGIGRPSTYAPTIATILNREYVEKQGTSLCPTELGIIV
                     TDILENNFHKFIDVDFTADMESKLDVIEEGNTDWKKIVSESYAPLKEAIEEALENIEK
                     VNMDEETDEICENCGSNMVIKYGRFGKFMACKNYPDCKTTRPIMNKIGVKCPKCEEGD
                     IILRKSKRGKAFYGCSNYPNCDFVAWNKPTGEFCEKCGSYMVEKVTKSETKTVCSNKE
                     CNKETKEHNDGKE"
     gene            complement(28316..29416)
                     /gene="dprA"
                     /locus_tag="PC466_001762"
     CDS             complement(28316..29416)
                     /gene="dprA"
                     /locus_tag="PC466_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HDF2769149.1"
                     /translation="MEKRDTYLWLKSIGGITTKTIEIIENEIVNIEDIFDFSEKEIYN
                     LKNISLNIRKNIVKYRGYAYLENIKELLYKKAIKYICKYDKEYPENLKNIYNAPKLLF
                     YKGDIGLVNNNFNIAIVGSRKPTAYGINCAKTISCQLSQYGVNIVSGLAIGIDAYSHI
                     GCMSGKSKTIAVLGSGVDNPLPKQNLHLSNKILENGGLLLSEYNINSTVAPYHFSNRN
                     RIISGLSDGVVVVEAAIKSGALITVDFALEHGKNVFAIPGNINSQMSRGCHKIIKEGA
                     KLIENIDDILNEYNIFNIIDKKINQKYDNISLNAKSKQIIEAIKREGNLHIDSICDYT
                     GIEIKYVNSIINELVLNELVVEMNNKTYSLNV"
     gene            complement(29435..31036)
                     /locus_tag="PC466_001763"
     CDS             complement(29435..31036)
                     /locus_tag="PC466_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YifB family Mg chelatase-like AAA ATPase"
                     /protein_id="HDF2769150.1"
                     /translation="MLSIINSSNLVGIDSFLVKVEVDVSNGIPSFNIVGLPGKEIKEA
                     RERVKSAILNSGYKFPSTRIVVNLSPADIKKEGAFLDLSISIGLLRELIKKDENYIRE
                     SMFIGELSLDGKIRKVRGILPIIMGAKTQNIKRIFIPIENIKESLLVDEIDIIPIKSL
                     KECVDFLNEEIKVDKVSIMSFLDDKSRKENGELEKDNSYIDCKYTKINNEESKYDEDF
                     KDVKGNYFVKRSAEIAAAGNHNMFMIGPPGSGKTMIAKRVRTILPDISIEEMIEVSKV
                     YSILGMINESKGIIDKRPFRAPHHTTTKQSLIGGGMDARPGEIALAHRGILFLDEIAE
                     FDRKILETLRQPIEDGYVNISRVKYSAKYPCRVLLVAAMNPCPCGYYMSETECRCRSN
                     EIDRYINKISGPLLDRFDIFVEVNSIKYSDFNSLKQEESSQKIKRRVENARKIQINRF
                     KKDNIKNNSEIKAYNLFKYCKLEKEASKTAEMIFNKYNLSSRSYTKLLKMARTIADLE
                     ERDLINSQCIIEAFSFRKAYYSYFK"
     gene            complement(31067..31411)
                     /locus_tag="PC466_001764"
     CDS             complement(31067..31411)
                     /locus_tag="PC466_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YraN family protein"
                     /protein_id="HDF2769151.1"
                     /translation="MNNKEKGDFGEEIAVNYLLSKGAKILEKNYRLRIGEVDIIANIG
                     DEVVFVEVKSRSNIKYGYPCESVDFKKRKKIIGVAKYYIIKNNLNNTPIRFDIIEVYL
                     LEKRINHIMNAF"
     gene            31596..32756
                     /locus_tag="PC466_001765"
     CDS             31596..32756
                     /locus_tag="PC466_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDF2769152.1"
                     /translation="MNRKKTFIFIRYLSLFILLISYLNHTENTLYPAITMIILFLIIN
                     NQVRFFSLSSENKFILISYFLELILIFIFCKYIKTFNPLYYVSLILDASFLIKEKYKY
                     ILFSLVIIFSFIIGLDKNLYLALESSSTLLIITLFSVYLENENLSKLYNQSLYDKLRV
                     SKDELKKANADLEIYANSIEELAILKERNRISREIHDSVGHSLSTTIIQLNAIEKLLK
                     DKPLISDLVHELREFVTESFQDVRRAISELKPIEYENYQNLLKIRELVNSFIKLTNIN
                     VRLTISKNTWNLSTNQSIALYRLVQESLSNASRHGKATEIRIFITFNPSNLIITISDN
                     GIGCNNIKRGNGLSSISERIYELNGKVEFDNSNTGFTIRASFPKFSGGDFFE"
     gene            32749..33393
                     /locus_tag="PC466_001766"
     CDS             32749..33393
                     /locus_tag="PC466_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2769153.1"
                     /translation="MNKIKVLIVDDEKLIRKGLNIILSSYDDLEIVGDASNGYEALEF
                     CKTNDVDIVLMDIRMKVCDGVLGTRLIKEYDSSIALLILTTFNDDEYIEDAMKFGASG
                     YLLKDSSDEVLHEGIRSSFFGNIVLDKSVAEKIMYPQKTIEQKHISDMYNLTEKEISI
                     IRLIANGLNNKEISQELFLSEGTIKNNITNILGKLELRDRTQLVIFAFKNKIVI"
     gene            33581..34516
                     /locus_tag="PC466_001767"
     CDS             33581..34516
                     /locus_tag="PC466_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2769154.1"
                     /translation="MDIVRVNNITKRFNDKLALDNISFSVKEGEIFGLIGPNGAGKST
                     LINIITNLMLPNSGDIQINGLDLSKDCIKAKSIIGLVPQELALIETLTPFDNLEYFGT
                     YYGLKGKLLQERITEALEVTGLTDVKKKKIKKLSGGMQRRLNIGIALLNHPKILILDE
                     PTVGVDPQSRNHIFNFIKNISKKQKTTVIYTSHYMEEVEHLCSKIFIMDEGKEIAFGD
                     NDYLKSLVSTNTKLIMEIKNINAQLIFDLKNTKGVVSILENNSLLELGVDKKLQLTDV
                     LSVVDKNNSKITRISYEEPSLEDVFLNLTGKNLRD"
     gene            34530..35627
                     /locus_tag="PC466_001768"
     CDS             34530..35627
                     /locus_tag="PC466_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2769155.1"
                     /translation="MKLYISVKTMLKVLKSSFMLNLIYFLALPLVLAGFLGMVTESIF
                     QNPIKTDLTSIVIYDKDNTKLSSNLTGYLKNDLSSILTVQKDDSKADLKLTIPKGYEN
                     NLLNEKSNNLSIEKLKSNDNIAILLQDILDTYHEKLYLNNSQKLSSEDFSKLFNKNSI
                     DTSIIKNNVKQNSYEYFALVSLGFFAIIFIMNSILSNYVSESKGLSKRLYSIPVTRVQ
                     FLIYDFIGFWIYSFIFLSLYVLFFRTLGVTFKGNFVILALLCALASYFMTSISTFITT
                     FFSKKYGTVIVYALLFLQTVFGGIFSIVNDVFTKFTSLSPTYLIGTLFSNYETFKTID
                     SIESLIFTCLIASTVLIALSIVKEKYKWREV"
     gene            35630..36694
                     /locus_tag="PC466_001769"
     CDS             35630..36694
                     /locus_tag="PC466_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2769156.1"
                     /translation="MIRLTIANIKRYIKNHALLVNMVLFPVILMFYLNFFTGNSENQS
                     MYFSPVAIVSNSSGKYEHKLIDSSKLKENSFGLNEQDKAMDLLKNNKVSAVFILDKNF
                     SSNIDNLKRPEVKCFKTENGGGSLWAESQIESFITNSLKLKIDRNIDDKLTKTNIIDN
                     SSGKNKNSFLIVFLICYFMYINAAHLASDLFSLKKSNTLKRLVSTKHNDIKIIFSIFL
                     GLFFTQAIVYTLTLVCFTSISNFKLTLNTLMIVLANSFVATGFVFWIARVFKNEGSIS
                     LMSTFYSLIGLAISISNMIPSLDKLSFMANLSKLTPFYWTIDAINNNGNILINIIVLI
                     LIGMVFVTAGSLNLRDFARN"
     gene            36935..37432
                     /locus_tag="PC466_001770"
     CDS             36935..37432
                     /locus_tag="PC466_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CarD family transcriptional regulator"
                     /protein_id="HDF2769157.1"
                     /translation="MYKIGESVMYPKEGACYISGLVTKDINHHIQKYYELTVIYNSNL
                     KISIPVLNADKIGVRPIMDENEVENFIQSLDKVDCLWVFDRKKRLKLYHDKFHSGDVF
                     EIVKLIKMLMIQDNSKQLCSTDKDFLNKAQRFALSELAAAQCKSYTIVLEEMKNHILN
                     SKNNN"
     gene            complement(37609..37857)
                     /locus_tag="PC466_001771"
     CDS             complement(37609..37857)
                     /locus_tag="PC466_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769158.1"
                     /translation="MSRKAYEEALVELEKFIDERKEIIKSAEDCIDKYIVDRTLPFDY
                     KDKCVEWQQELLDIAEAQVLEANELGVLLEEKKELEEE"
     gene            complement(37923..38939)
                     /locus_tag="PC466_001772"
     CDS             complement(37923..38939)
                     /locus_tag="PC466_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HDF2769159.1"
                     /translation="MEYNELLKSARENLNGSCKVCKVCNGVACAGEVPGMGGKGSGSS
                     FIENSKSLEKVKVNMRVIHDVSNPDTSIEMFGKKMSAPIFAAPVTGTTLNMGGKINER
                     DYIEPVVAGCANSGIYAMVGDTAVDAFLMENLDVVKKYNGAGIVFIKPWDNENIIKKI
                     RLAEEAGAFAVGVDIDACGLVTLSLHGKPVLPKNVKQIKELVKSTKLPFILKGIMTVE
                     DALMAVEAGVYAIVVSNHGGRVLDCTPGACEVLPKIADAVKGKVTILADGGVRTGLDV
                     LKMIGLGADAVLIGRPFVTASFGGATDGVETYVNKLQSELSSSMILTGCQTIKDIDGK
                     VIYK"
     gene            complement(38997..39764)
                     /locus_tag="PC466_001773"
     CDS             complement(38997..39764)
                     /locus_tag="PC466_001773"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HDF2769160.1"
                     /translation="MQDKSVREIKEIIETLEVEKYMEYIELLRVDERKSVQGLAIKLA
                     KKLDNIRKEEERLETINIFENEGYDKGYLYIGGIDEAGRGPLAGPVVASVVVFKKDTK
                     IEGVNDSKKLSEAKRDELFEVIKEEALDYGIGIVNNEEIDEFNILNATYMAMKKAINC
                     LKKAPDYLLVDAATIPGIDISQNPIVKGDSKSISIAAASILAKVTRDSIMYQYDRVYP
                     EYGFKSHKGYGTKEHYEAIEKYGITPIHRKSFLKNIL"
     gene            complement(39832..42021)
                     /locus_tag="PC466_001774"
     CDS             complement(39832..42021)
                     /locus_tag="PC466_001774"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobalamin-dependent
                     ribonucleoside-diphosphate reductase"
                     /protein_id="HDF2769161.1"
                     /translation="MKYIIKRDGTKELFSKSKIEDAVYKASINSEGGVDRELAYDISR
                     KIANDYNSMEKCLSVEEIQDIVEVLLMESNRKDIAKHYILYRERRSEIRTKAWEFDEL
                     QKSIWKNKYRHNGESFDEWIKRISNNSSRISKLIRQKRFLFAGRILANRGLQKEGKKV
                     TYSNCYVIEPPKDSIEDIFDTAKKLARTFSYGGGVGIDISKLRPKGAKVNNAAKHTTG
                     AVSFMELYSMTTGLIGQRGRRGALMISMDVNHPEIEEFIDIKTDLEKVTKANISIRVT
                     DEFMQAVREKKLYNCTFEVETTGEKIVKIVNAYDLFNKFVKNNWDYAEPGILFWDKIK
                     TYNFMSEDKNFCFSGVNPCAEEPLPSGGSCLLGSINLSEFIIQPFGEHATFDINKLKS
                     CVREAVVALNDVLDEGLNLHPLQEQRDSVHKYRQIGLGVMGIADMLIKMGIRYGSDES
                     LELCDLIGKTMLNEAVKQSALIAKEYGTFSEYKYENISKSKFFIENLNEDTKEMVKKY
                     GLRNSQLLTIPPTGSISTMIGISGGIEPIFNLSYIRKTESLHDEDVYYKVYTPIVKEY
                     MDKKGITDEECLPDFFVTAMNIGYEERINMQKVWQKYIDASISSTINIPFETTVEDVF
                     NIYIKAWEAGLKGVTIFRDGCKRSGILINEKKEENNKEDKKENSKKEYYKNNKKEKDN
                     KDEKAKEIINKNFEEDEKFVCPECGSEGIAHTGGCSICLKCGYSGCN"
BASE COUNT        13445 a         7327 c         4497 g        16878 t
ORIGIN      
        1 aaatttatta taggagagaa tgttatatgt ttaaaatttt tcttttttct agtgaacaat
       61 ttgtaagtct ctttatattt ggattatttt tatactattg tccaaaacta accaaaaata
      121 ttttacctta tagctataca gttgagaaga taatttgtac attacttgta ataattatgg
      181 ctctagagca attattactt atttcttcag gtaattatag tactctaaac tctttaccaa
      241 ttggaatcaa ttatatctgt atatatctgt gtatagccat actaattttt aagcagtatc
      301 atctttttaa tatatttttt tcttggagtt tagtttgttc agttggagaa ctcatttttt
      361 ctaaaaactt gggctatgaa tttcctagct taatatattt tatatttatc ttctctaagt
      421 gcttgataat ttatgcagat atatatatgg ttgatgttag aaaatttaga gttaacagat
      481 atgcacttag agataactta gctatatgtt ttatttattt ttcattcata tttttactaa
      541 acacatttac caactcacaa tactattatg gttttttaag tcatagcaca actgctattt
      601 ttacgtttat ttttgttact agtattatgt acatacctgc tcttttattt aatagagata
      661 cttttatact tgagaaaaag aaaaagagta aataatttac ttaaataaaa aataaagcca
      721 catagataat cttaaattac aaaaatatcc atgtggcttt ataaattata ttttataatt
      781 gttttttaga tttctgccaa atagtataat gttctaacag gttctcctgt agcccccttt
      841 gctttgtatc caattgattt tgatgatgta cttgtccccg ctatatccat atgtatccaa
      901 ggagtattcc caacaaattc accaataaaa gctcctgctg ttatacatcc agcattttta
      961 ccaccagtgt ttttaaggtc tgcttcttct ccttttatca tatctttaaa ttcatcataa
     1021 attggcatct tccataccct ttctcctgat aaagtggcag ctttttctaa ttcacaataa
     1081 aaatcatcat tatttgttac tataggagtt gcaacatttc ctaacaatgt taaagcagca
     1141 ccagttaatg tagctacatc aactaccttt gttacttttt cattgtttat aatgtagtat
     1201 attgcatcag ctaatgtaag tctaccttcg gcatccgtat ttaaaacttc aatagttttc
     1261 tttgccatag aactaattat atctccaggt ttgtatgaac ctcctgataa agcattctca
     1321 catgcagcca ctactgctat aacatttttc tttaatttac tttgagatat agcacacata
     1381 gcacctataa cactcgcagc accagccata tctgtcttca tatctagcat agaagcattt
     1441 gattttaaag aatatccacc agtatcataa gtcaatcctt tacctactag acctaatata
     1501 tctgtacttt ctttatctcc aaagtatctc attactatga atcttggttt attgattgaa
     1561 cctcttgaaa cggcgaaaaa agcatccatt cccaatgcct ttattttttc ttcttcataa
     1621 acatcaacat taaacccgaa ctctgcacca agtttaactg tttctattgc taatgttttt
     1681 ggatatatta cgtttgatgg ttcattaact agatttctag ctattatagt tgaattagct
     1741 aatattttag ccttttctat ttgacactca acttcttttt cagtaaatat agttatagta
     1801 tcaacttctt ttctttcaaa atccttactt tttgtcttat acttatcaaa cttataattt
     1861 ccaagtaata tcccttctac aaaagaacct atttcatcac tatttaaatt aagattaagt
     1921 acattaacat cactactctt atatgcttca tttttcaata tattttttaa ttttttacac
     1981 aaattaccac ctatgattct aattttttct ctattcaata actctctctt accaaaacca
     2041 acaagacaaa catttaccaa gttgttattt tcaaccaatg ttacagtatc tatactattt
     2101 tctttagaat taaaatttct gcttatcata tttattttat caaatgtcgt agaaacatct
     2161 tctccctcaa atagagctac tactgttata gcattttcta aactttttaa tatctcttta
     2221 gaatacttta tattcataat aaattctcct ttttaaaata attgttctat tatattttta
     2281 gactcttcca aagaagtaaa taatttatct ttattatcta tatctaagca atccatttta
     2341 tcacttatta tagatacaaa ctttagtatt tcattatcca atatcttttc tccattttta
     2401 gttattccat aaaaagtatt tcgtctatct ctactatctt cttccctata tacatactct
     2461 tgctcaacca atttattaag tagtatacac agactagaag tagatacatg taaatctcta
     2521 cttagatttt taagctctat tttatcatgt tttcttattt ttactaaggc aaagaactgt
     2581 ctttctgtaa gaaccttatc ttttttatat ctttcgttat taataatctt tattaaatta
     2641 tgaaaattat tcatactttc taacaacaaa atagataatt ctttatcgct cataacattc
     2701 acctcaaaac taatgattta taactccctc ttatatctca aatgcgttta tatatctata
     2761 atataatact tcttttcttt ttataattat actatatatc aactttatta tctatttaaa
     2821 ttgttttaaa ctaaaatctt attagatata aatgtttaaa gtacacaaca aaatagtggg
     2881 atttatacta accccactac tttacttaaa actatataca tatttaaaaa tattttattc
     2941 ttacatattg tttttatctt gattcttatt actttgtgat atattttgaa ttttctccaa
     3001 tactctagga gttatagata atatattatc cactagattg atattactgt ctaaactcat
     3061 tattctagtc tctccacttt caactactac aaatgctact ggttgtacag atatagcccc
     3121 tgcgctacct ccagcaaaat tcgtatctga tttttcattt tttaattcaa tttccctatc
     3181 tttatcatca tatccttttg agtattctcc tcctcctata ccaaagccaa ttgtaacctt
     3241 tgatataggt acaaccactg tagtatctgt ttttataggg tctcctataa tagtatttgc
     3301 atctatagaa cctttaattg tttcaagagt tgtttccata agactttgta tcgaacctgt
     3361 tgctctcatt actatcacct tccttatttc ctttattttt attcataatt ttattaatca
     3421 ttattataat attaaataaa gcttttattc ttggccttat atgtatcctt atatttccta
     3481 aaacataatc ttttgtaaaa tctggattta catttaaata cattttttct gcatcaatca
     3541 tattaaataa atttccatac aaagtattta tcaatacata tacagaagat gttaagccaa
     3601 tatttccagt tccaaaatta atatttgaat aaagttcatg tatttttatc ttttttaata
     3661 atctataaat gctcaaaagg tcatcagcta ataatatact tgaatctata ttattcttca
     3721 tcccctcttt tttatcatta tttttactat tttcagctgg ataaagttgt ctatttatat
     3781 ttattaaatt aaacatgtat tttatattaa gctttaaaca aatatctttg ttgtttatat
     3841 cagctattat taagatgttt atatgagata ttaaaatcaa catagttaca cttataataa
     3901 aaattacagc tattattaaa tacttaaaat taaataattc attaagctcc atgtttatat
     3961 tatcatcaaa aaattactat ttatacttaa ttatccatat ttattttaag agaattataa
     4021 ttttatattt atacaaaaaa acacaacaac ttagagcatt ttaaatcttt taaaatttaa
     4081 aattacatac taaattattg tgattttata tttttattca tttgttgcca cttcttgata
     4141 attttctata ggcggcaatt cttcaagact ttctatattc aacaacttta aaaattcatc
     4201 tgttgtttta taaattattg gtttccctat cttattcaat ctaccagctt ctcttataag
     4261 ttcattttca aacaaagttt gtaatacctt atcacatttt actcctctta tatcctctat
     4321 ttctaccttt gttattggtt gtttgtaggc aattatagta agagtttcta atgtagcttg
     4381 gctcaaactt ttctttttct ttggttcaat aatcttcttt atatattctg catagtcttt
     4441 atttgtacac atttggtact tattctctag cttgattatt tgaatacctc tattttgttc
     4501 tctgtactcc tcaataagta aatttaacat aatctctatt tcttttgatg aaagttcttt
     4561 atttattata tagtttaatt cttttatact tattggttcc ccatatgcaa acataacaga
     4621 ttctataata tactttatat cttctctttt cattttaaca ctccgaactt tttcttatta
     4681 gaatatcatc aaaaaatatg tcttgtacta ctactatttc tttttctttt ataagctcta
     4741 atatagataa aaaagtagct attatttcat cattttcata tgattttata atatttgtaa
     4801 aagtaacttc aatcttatct tttataatat ctcttatata caatatcttt tcttccacag
     4861 atattatctt cttccttact attttgtcta gtttctcatc attagcattt tctatctgtg
     4921 atgttttaac tttaaatatg tatggaagta tattttttat tgcttcaatt gatatatctt
     4981 ctaaatccac attgtcatca ataattatct cttctttatt tctataaaat ctctcattaa
     5041 cataagttat attttctttt atatcttgtg atgctacctt aaactttcta tattcttcta
     5101 acttttccat aagttctatt cttgggtctt cttcttcatc tttttgctta taaagcagat
     5161 atttagactt tatctctaaa agttttgatg ccatagttat aaattcacta gttatctcta
     5221 aatccatttt atctagcatt ttcaaataat ttagatactg cttagttata tctattatag
     5281 atatatcctt tatatctatt ttatgctttg ttattaaatc ataaagtaaa tctaatggtc
     5341 cctcatagac ttgtaattgt atattatact tcatatcaat ccctctttaa tctgtttatt
     5401 atattaaaca aataaatata ctatttttag caacactgta tatattggtg atagtattat
     5461 ttgatatata ccagtaaata aagcaattaa taaaattata taactcatac tttcaaattt
     5521 atacaaatat tcattccatt tatatggtac aaatgtagat ataactcccc atccatcaag
     5581 tggaggtatc ggaagtaagt taaaagctgc aaatcccata ctatatataa gcacatatcc
     5641 agctattgta tttatagcat acatatgcac atacttattg ataattacac acagtatagc
     5701 agtcaaaaca ttacaaaaaa cgcctgcaag tgaaactatc aggtttccta tcttatagtt
     5761 tttaaaatta tttggattta ctggtactgg ctttgcccac cctatcttaa ggataaacat
     5821 agccaaaaga cctattggat caacatgtct tacaggattt aatgtcattc taccataagc
     5881 tttagctgta tcatctccca ataagtgagc tgaataagca tggccaaact catgtattga
     5941 tattgccata gctataccaa ctaaacttgc tactatttct cctatattca tacttaacat
     6001 taatgtacat ctcctaaatt aaatttttaa tattattata acaattaaat agcttataat
     6061 caaaattatt ttacattata ataattttaa cttctaggca taaaattaaa atttgctttt
     6121 tattttataa cttttattat tatatcatat tcattgtgaa aatataataa ttacacctac
     6181 tgtaagtgta atattatatt gacatgaatt gacattattg tctcttagtc aatattatac
     6241 aagaagtata aaaaaatatg tgttacactt tgtataacat gaaaggaggt tacctaagtg
     6301 agacaagaag aacgcacagt atgctttgat agggaattaa aaattgaagc atatagattt
     6361 aaaggcataa tgcaaaaatt cccaaaccat tttcatgaac attatgtaat tggttttata
     6421 gaaaaaggtc aaagatattt atcttgtaaa aataaagagt ataccacaag tactggagat
     6481 ttgctacttt ttaacccttt tgacagtcat acttgtgaac aaatagatga taaagtactt
     6541 gattacagat gtatcaatat taagccagaa ataatgaaaa aaaccgtctt tgaaattaca
     6601 ggtaaaaatt atttaccaaa atttaatcaa cctgttatat ttcgcagtga gctagtacct
     6661 ctactacaag aattacacta tataatcatg gaagaagaat tggattttaa aaaggaagag
     6721 ctttttttct tcctaattga gcaattaatt gaagaacata cagagccaaa tttgcaatct
     6781 aacttggaaa atacaaatat agaaattcaa gcagtatgtg attatctaga aaataattat
     6841 gctgaacata tagtacttga cgaattaagc actatagcag gtatgaataa gtactctcta
     6901 cttcgtaatt ttacgaaatt aaaaggtatt acaccatata gatacctaga aaatatacgg
     6961 gtaaacaaag ctaaaaagct tttagaaaaa ggcgtagaac ctatagatgc tgcgatacaa
     7021 acaggatttg tagaccaaag tcactttaca aactttttta agaattttat tggtcttaca
     7081 ccaaagcagt atcaaaatat atttataaat gatgattcaa acaactttaa ataaggtaaa
     7141 aaggagaaat aaaaatggaa aataaaaatt caaaatgtgt catggtaata gacgaaaatt
     7201 taccaatggg aattatatcc aatacagcag ctataatggg aattacacta ggaaaacatg
     7261 ccccagaaac tgttgggcca gatgtaattg acaaaacagg taatagccac ttaggaatta
     7321 ttgacattcc tgtacctatt ttaaaaggaa acaaagaaat aataaaagat ttacgtaaaa
     7381 aattatatac tttggaattt aacgatttaa ctgttgtaga tttttcagat gtagcacaaa
     7441 gttgcaatct ttatgaagaa tttacacaaa agattgctag tgttccagaa gatgagttac
     7501 agtattttgg gatagcaatt tatgggaata aaaagaaagt gaataaactt actggtagta
     7561 tgcctttact tagataattg ttaaacaacc ctatatatga tattaaatca aatgatattt
     7621 taagatacat aaacttttct atatttctat aaaaatcata agattataaa atacttctat
     7681 atggtaaata aaaatacccc tatggcaaat aactacataa gggtattttt tatgtgtatt
     7741 ataatcatat ctttgtgtat tataattata tttcatctga taattattta tatcatatta
     7801 tcaattattc tttgaagcat ttgtagatag cttgccttat ttatatcctt agtatttatc
     7861 aattccactt cgcctattac ttttttatct ttacatatct ttatttttcc taaaacagtt
     7921 ccctttttaa ttggcatctt aggatttttt actatttcaa ttttcttctc aaattcttta
     7981 gagcttcctt ttttaataag agcatttaaa tcttctttag caaccaattt aactttgttt
     8041 tcatcagcct tatccaatgt aagtgttgct atattatcac ctttactaca taacttaaca
     8101 ctttcataat tagcaaatcc atagtttaaa aggctagagg catcattaaa tctttctgga
     8161 gaagtctctg ctcctaaagt tgcagcaact agatgagtat tacctctctt tgcagatgct
     8221 gataaacagt attttgcttc ttgagtaaaa ccagttttaa caccagttgc tccttgataa
     8281 tgctttataa gtttattagt atttgcaaga cctactgtaa cttgtttctt ccctactaca
     8341 accttatcca tccatgtagt taagtattta cttatcattt cgtgttttaa tagttctcta
     8401 gacattaaag ctatatcatg agcagatgta tagtggtttg caactggaag tccatttgta
     8461 tttgcaaaat gagtatcatt catatttaac tcttttgctt tagcattcat tctatcaaca
     8521 aatccttcaa cacttccagc taagtgttca gccatagcaa cacaagcatc atttgcagaa
     8581 gcaacagcta taccttttaa taatgtatca accttttgag tttctcctgg ctctaggaat
     8641 atttgactac cacccatact agatgcagtt tcacttactt gaacttcatc atcaagctta
     8701 atcttgcctg aatccaaagc ttctactata agtagcatag tcattacctt agttacacta
     8761 gcaggaggaa gctttttatg agcatccttt tcatataaaa tttgtccact accaacatcc
     8821 atcaaaattg ctgattttga agatatattt agttggttgg catcagcatt ttccttatta
     8881 tttgcaaaag aaaagcttaa aggagtaagc gcaattaata tagccaaagc agtactagct
     8941 aattttttca tcgatgtcac ctcttaaagt ttatttaaac ttattttctc acatttaact
     9001 ttttttattc taaatgccta gatatacctt gacctaaatt ttttttcttt tcaagctttt
     9061 taaagtaacc ttctaaaaca cctttattag acgcattttc tattatttca aaagcatctt
     9121 cataattcat tccatactct cctgctattt ccatttttgt ttgttttaaa gcttttatag
     9181 cattttgtct tgaaacatca tccataagaa tcctcctatc agtaaaattt atatataagt
     9241 agtttttact aataaaagat tgttataatt ggtattttat gtaatatata ttttttttaa
     9301 atgagtatta aaaagacctc ttgtaattct taagataata tcaattggat ttttgatatt
     9361 actttaaaaa ttacaagagg tctaattttc aaatttatag tttttttata ttatacttcc
     9421 attatgatag gaagtatcat tggatttcgt ttagtttttt gatataaata ttcttttagg
     9481 ttttctttaa tattattctt taaataagcc cattctttaa tatttttctc ttcacattca
     9541 tttagaacat tcttaattat atcctttgct ccatccatta aatcttctga ctctcttaca
     9601 tatacgaatc ctctggaaat tatatctgga cctgctaaga ccttaccctc atccttggaa
     9661 atagtaacta caactatcat aagaccatct tctgataaat gctttctatc ccttaaaact
     9721 atattaccta catcgcctac tcctagacca tcaactaata tgtttcctgt ttgtatacgg
     9781 tttgctacct tagcagagtt tttatctaat tctaaaacat ctcctgtttg catgacaaaa
     9841 atattttctt tatccatacc aagctgttca gctatttcag catgtctttt taacattcta
     9901 tattcaccat gagctggcat aaaaaacttt ggtctaacta atgcatgtat aagttttaat
     9961 tcttcttgac aggcatgtcc agaaacgtgt atatcagcta tatcactgta tactacttct
    10021 gctccttttt caaataagaa attgattact cttgatatta atttttcatt tcctggtatt
    10081 ggatgagcag atattataac taaatcgcca ctctttattt ctactttttt gtgctctgaa
    10141 aaagccattc tagcaagagc tgacataggt tcaccttgtg aaccagttgt tattatcact
    10201 aattcactat cttcatactt acatatatca tttaaatcta taagcatgtc atcagaaata
    10261 tctaggtatc ctaattcttt tgcaactccg actacattga ccattgagcg acctgatata
    10321 gcaacttttc tattaaactt ttcagcagta tttattattt gttgtaatct gtgtatgttg
    10381 gatgcaaagg tagcaactat aattcttctg ccatttcctt ttgcaaataa ttcgtcaaga
    10441 cctaccccaa cagtcttttc agacatagta aatcctggtt tttctgcatt agtactatct
    10501 gccagcatta aaagaactcc ttttttgctc aactcacaga ttctatgcat atccataaca
    10561 tctccatcaa taggagtcaa gtcaatctta aaatctcctg tgtggtatat tataccttgg
    10621 tctgtgtgta ttgcaataga gtaagcatct ggtatactat ggttattttt caaaaactct
    10681 acttccatat tatcaagctt tataacttgt ctaggaccta taacatttaa cttaacatta
    10741 ttcattttat gttctttaag ttttacttgt ataagaccta tactaagtct tgccccatat
    10801 acaggtacat ttattttctt taatatatat ggaagagctc ctatatggtc ttcatgtcca
    10861 tgtgtaataa atataccctt tattttatcc ctatttttta ctaaataagt tatatctggt
    10921 ataactatat ctactcctaa catttcatcc tctggaaaac taagtccagc atctataaca
    10981 attatttcat ctttatactc aacaacagtc atattttttc caacttcgtt aagtccaccc
    11041 aaggccatta cctttatctt gttggtgttc tttttgaaca attgcatcat ctccttctgt
    11101 ctatttaatt ttttaacacg ttctacaatc ataaataata tcaaatcacg cactcgctac
    11161 cagttattct tattgtacca taattcgtat catattttaa gctatattta aaatacattt
    11221 aacgtattat tttgacaaac ctattttatt ttgatatcct ctaaatatta tatgatttaa
    11281 tatcggataa tttaggagga tttatgcgtg gtaaaactca ttgtgcaata ggaatcttaa
    11341 cagctatcca aacatcttta atatttaaaa ttcctatatc tttagttgat attttagttt
    11401 cagctacttt tgctgtacta cccgatttgg ataaatctaa ttctatggtc tcaaatttca
    11461 ttctaaaaaa caatgtatcc aaatacatat atagaatttt tatatatgct gttaatatta
    11521 ttattttctt tatttcaata aatataaatg ataattttta tttaagcgca ataattacat
    11581 ttgttgcaat tataattatt gaagcaaaac taacccacac atttctaaga aaagtttttc
    11641 tatcattaat atttatacta ttagctatat gcttatacat catagaagtt gaaatatatt
    11701 ttacaatttt ttgtctaatg ttgtcaattt ttccctggtt aaagcacaga agtttttctc
    11761 atagcatatt tgcaactata atagtatatt ttttactaaa acagatagaa ttaatcacta
    11821 atattaataa tttatctttt tatggtacga ttggttatgc aagtcatatg tttttaggag
    11881 atttatttac aaagcaagga ataccaattt tttatccgct aagcgaaaag aaaatttctt
    11941 taggtttttt aactgttgga ggaccattta gtaatttcat agaaaaatca ttcatttttg
    12001 tacttatagg attaattata ttttcaatat taaaactata agcatcttga aaactgtata
    12061 tttgcatttt gtagatggtt tataataaaa aatggaagaa tagcatagaa tataaaagtt
    12121 ctatactatt cttccatcga cattaagcaa tagaagttta ttcttctgaa tcgcttactc
    12181 cattacactc gtcacataat ccataaaatt taacatcatg atcaagtatt ttaaatttgt
    12241 acaatgattg tatctctttt tctatattgt ctaaaaggtc ttctttagct tccattatct
    12301 ttccacaatt tttacaaata agatgatgat gattatgaca gtcttcttta tgtagactaa
    12361 tctcatatct tatacatcca tcgtctaagt ttagttttga tattaatcct atttcatcca
    12421 atagctgcat tgttctatat acagtagcta agcctatttc aggacagtca accctaacta
    12481 aatcatagat ttcctcacta cttagatgtg aatggtcatg tttaagcaat atttcaacta
    12541 ttgctcttct ttgtggcgta atcttaaaac cagtttcttt taacttgtct tttaataaat
    12601 ccattgtatt tgccataaca tcacccttac tattttcaat tgataatctt tattaaataa
    12661 tattgtaatt gataattcat tttttgtcaa gacatttaaa taaatttaat ttattctcat
    12721 aatataaata tatacccata aaagatatat tattcaccaa aattcataaa ttttttggta
    12781 tttttaataa aaaacaaaaa aacagatata tactataaat gcttttacaa ttaataaggt
    12841 ttaattaaag caaatataat aaatatctga tttttatata caaacttaat tacttatcta
    12901 gttaagtcca tttgattcat cttcgtcgta atttaaacct tcttcttcca ttatagcagt
    12961 atacacagct acaacagttt catactcttc atcactttcc aaaggtatta atatttcacc
    13021 ttcttcatcc tcatcaattc taaagattaa agcttcttca gcttcttcat catctaaagg
    13081 cattaatatt gcatactctt ttccttctgc ttctaatgtt aatattattt caaattggct
    13141 ttcaacgcca ttttcgtcta ttaaatttat tatattttct tccataatgt cattcacctc
    13201 aaatttattt ttatttttat tatttatatt atatatcata agtattcaat tttatagttc
    13261 ttttatgaat ttattttaaa atctaaatat ccttgcaaaa ttattactgc tgccaacata
    13321 tctataacct tttttctttt ttgtctacta acatctgctt ctaataaaga cctctctgcc
    13381 gctactgtag aaagcctctc atcccaaaac tctacatcaa tacctgtttc tgcttttacc
    13441 aattcacaaa acttgattac tttttctcct tgtggaccta aagttccatt catatttttt
    13501 ggtaatcctg atacaatttt atttacttgt ttttctttta ttattgcttt taactcttca
    13561 atatcttttt tcttgccaac tctttttatt gtttttacac cttgtgcagt taatcccatc
    13621 aaatcactca cagcaactcc aatagtttta tcaccaacat caagacccat tattcttcca
    13681 tctaacatag ttcctccttt atctatttat attctataga ttaaatacat attctgaacc
    13741 tctcataact aaggtcacag gcttcctgct tcatagaatt ttgcataatc aatcataaaa
    13801 attgcaatat gattttttat gtaagcatcc agtttacatt aataatcata ttgcattttt
    13861 tatttaaatc ctatatgaac agtaaaaaat tttttagttg tttttttcaa atattatcat
    13921 atttatattt attattatta gtggtataag tatatatata gatgctgtag atgcagcaac
    13981 tattccagaa tcattaacta aaagagtaat tatacaacca accatagatg caataaaccc
    14041 tttaaacaag attggaaaat tattcattat ctttctaaag tgtctagatg gtttaaatat
    14101 aagtactgca attactccaa ttcctacaag taaaatattt acccatacac ttgtctgtgc
    14161 tagttgcata ttcatttgaa tttttcttcc aaatgtttgt aatatctctc ctggtccatt
    14221 taggaaaatt ctctgtacaa acatacctaa atgagattca ctacctgaaa gtatatctaa
    14281 agctgcaaat gcaaaaacga caactacagc tgaaacagct aataatacag ctttcttaaa
    14341 atctatttta atgtcatata taagcattat aaacaacaaa tatgctacac attctgatat
    14401 agctccacca acatttgcac ccattgaagg atatgcacta gttataagta ttattaacga
    14461 aaaaattaca acaagtaatt tagatacctt cttataatgt aataatactg ctaagccaaa
    14521 tactgcactt gctatagtta caccttcata ttcatttcct acaccatagt acctagctcc
    14581 tatgacagca tcataactca ttatgttatt ttgcattaag tatgttccaa atacagaatc
    14641 tataactatg actaaaatag taagtgttgc aaaaaatccc atgtgcttta tatcattgtc
    14701 cttaaataat tttctaccta acaagtataa tattagcgta gtcgcaaata ttcccaaaga
    14761 tattgaaatt ggagttttaa aattcatcaa aggagctaac ataaatgata gtggcattat
    14821 tatgcctaat tttataaact ccttaagtac tttgaataca cgctctttat gtggcatata
    14881 atttctaaag aaaatcgcaa acatggcaat tacccaagaa gcagatatta cgcctacaaa
    14941 gccatttata atagttgacc ttattgaaga tatagacact atcctttcat aaagtgattt
    15001 tagatagcca acattgtcct ctttatttac taaagtataa cttctaccta ccatctcttt
    15061 attttcaaga ccaaatgtac ctagtatatc tactccaaca tctaaattgg caacaattcc
    15121 agcctttctt gttgtggcag attccagtag acctttccct tctccactaa attttattat
    15181 tggagaaagt cttctcttat tcttataatc taggtcactt ggaaatgcac ttgctatata
    15241 aacagtgtca ttttctccaa ccatagaaaa tacttgttca agatatttat ttatattttt
    15301 tacaatattt ttcttcattg taccataagt attatcattt agatttaatc tatacatatc
    15361 taatctatat gtatctccaa gttctacaaa tatagcatca ctatttttat aggatttttt
    15421 agtttcatct agtaatttat cgtagtctgt agatattcca aatggcattt tagaatcttt
    15481 cttattaata ttatcaatat tacctgaatc aatccttcca tattggtcca tagctactaa
    15541 acataagttt ctatttttaa ctaattgatt attttcaatt atatcagcat ttccaattac
    15601 agatgtcttt aaaccatttt ctgataaagt ttttcctaat gaccctaaat ttgctccata
    15661 ttctccatac tcaagatttt catttataga tctattaatg cctaaatcat ttatttcttt
    15721 agctttttga cctgttgcga cttcaaaagc tttagcagta tcttggtcta ctttttgaaa
    15781 attgatatag tcttcagtag ttacactagc tcttgttcct gcacccatac ttgcataaga
    15841 ccttctatca tcagtacctt gatcccctct tatattcatg agagctacat agcctctctt
    15901 ttctatctca tttttcaaga ttggaatatt catcatactt ccaagattgg tcctattcat
    15961 atcaataaat atgaccttgc ctttttcttc agcaaaacca tagctagcag ttgatacaaa
    16021 aatcataatg actattgcaa acaacgacat aatctttttt ctcatttatt tgacctactt
    16081 tctattcaga tagtgcgtga ttacttcttc aagtatctca tctctttcaa attttttaat
    16141 tatagctctt gcatttttat gactagttat atagctagaa tcaccagaaa ggagataccc
    16201 tataatttga tttatagggt tatatccttt ttcaactaat gctttatata caaaatcaat
    16261 agtatctcct acactcatcc tatcttctgg tattccttca aatttcatag tgtagtctaa
    16321 atctttttcc aaactaaaaa cctccttgag tgaatgttat ttaacttgtg tcttaataac
    16381 ctcacttgca tagcttaaag cttggtcaac cttagataca tcactagctc ctgcttgtgc
    16441 catattaggt cttcctccac cttttcctcc agctattttt gcaacttctc taacaatatt
    16501 acctgaatgt attcccttat ctaatacatc tttagtggca gtaactacaa agttaacttt
    16561 atcatctact acatttgcaa gtactactac accagaacca agcttatctc ttagattatc
    16621 tgctgtttct cttagtgtat ccatatccat accttcaaat ttattagtta tcaaattaac
    16681 tccatttact tcaactttag aatcaaaaat agaatcaact gattgtaaac tcatcttagc
    16741 tttcatatca tgcaattctt tagataagtt tttattttct tctaataaag aacttattct
    16801 ttgaattaaa ttatcttctt tagattttaa gtttacacaa acttcagaga taattccatc
    16861 tctttctttt aggtattcat aaacagcttt tcctgttatt gcttctattc ttcttacacc
    16921 tgctgctact ccaccttcag ataatatttt gaacattcct acttgagaag tatttgtcaa
    16981 gtgagttcct ccacaaagtt ctgtagaata atctcccata gaaactactc ttacctcatc
    17041 accatatttt tcaccaaata gtgctgtagc tcctttttct ttagcttcct ttatattcat
    17101 aatatcacat tttatgtcta aagatgataa aataacatta tttacttttt cttctattac
    17161 ttttaattct tcatttgata tcgcttcaaa gtgagtaata tcaaatctaa gtctttctgg
    17221 agttactaaa gaaccagctt gattaacatg ttctcctaat acttctctta atgccttatg
    17281 aagtaaatgt gtagcactgt gatttcttgc agctgacatt ctagtttctc tatctacgag
    17341 tgtctttact ttgtccccat tacttattct tcctgatttt attataccta tatgttttat
    17401 actattatta gcaccttttt tagtatttaa tacttctaaa actaagtttt cattagttat
    17461 caatccacaa tctccaactt gtcctccacc ttcaggatag aaagtagtgt tatctagtac
    17521 tatagatacc ttatcgcctt cttctgcact ttgaactagc tcatcatctt taactatagc
    17581 ttcaatagtt ccttcaccat aaatttcact atacccatta aatgtactgt caactgtaga
    17641 ttctaatttt gatagagggt cttccttcca actttctcca tccatatttc ctctagcatt
    17701 tctagctctt tctttttgct tttccatttc ttcattaaaa gcttcttcat ctacagatag
    17761 atgttcttct tctaatattt ctttagttaa gtctataggg aagccataag tatcatatag
    17821 tttaaaagct tcttgaccac ttaggacagt ctttccttca ttttttaata cttctatata
    17881 agagttcaat atttctgttc cttggtctat agtttcattg aatttttctt cttctattcc
    17941 aactactttt ttaatataac tttctttttc aactaaaact ggatatgctt tatcatttac
    18001 ctttataact tcatctatta gtttctgtaa aaataattct tttactccta ataacttacc
    18061 atgacgagca gcacgtctaa ggagtcttct aagaacatat cctcttcctt catttgatgg
    18121 aagcactcca tcactaacta agaatgttac agctcttatg tggtcagtta ttattcttat
    18181 tgatatatca ttttttggat tctctccata ttttactcct gttaacttct caactgcttc
    18241 tagtatagat ttaattgtat caacttcaaa gatagtgtct acgccttgca taatacatcc
    18301 cattctttca agacccatac ctgtatctat attcttgttt tctaatagac tataatttcc
    18361 ttcttcatct ctatcaaatt gagtaaatac atggttccaa aattctaaat acctatcaca
    18421 atcacagcct ggtttacagt ctggattgtc acatccatat tcttctcctc tatcaaaata
    18481 tatttctgaa caaggaccac aaggacctgt acctatttcc cagaaattat catcttttcc
    18541 aagtctaacc attctttctt ctgggaaatt catttctttt gcccatatat cataagaatc
    18601 atcatcttct tcatatacag tcacccatat cttatcttct ggtatattta gccattctgt
    18661 aacaaattcc catccccatt tgattgactc tcttttaaag taatctccaa atgagaagtt
    18721 acccatcatt tcaaagaatg tagcatgtct tgcagttata cctacatttt ctatatctcc
    18781 tgttcttata catttttgag atgtacacat tctcacactt ggaggtactt ctacacctga
    18841 aaagtagttt ttcaaaggtg ccatacctga gtttataagt aacaaactct tatcattgtt
    18901 tggtactaaa gaataactat ttgctacata atgacctttt gactcaaaaa attctaaaaa
    18961 cttacttctt atttcattta atcccatctt ttccatatca tgttcctcct aataaatttt
    19021 attttttcgt ttaaataaaa aacctcgtcc ctataaataa atttataggg gcgaggacaa
    19081 tcgcggtacc accctaatta tcatacaaag tatgatatct tcggaaaacc ttagctataa
    19141 cgtaactacc gtcaatctct acttaaatct tctttataaa agataaattg ttcaagattg
    19201 ctactaaaag gctgcttcaa atatcatatt ctaagggctt ccagcatttc cctctctctg
    19261 taagacatca aatattttac tattccttat cactgtattt gttttttaat taatatacta
    19321 attatattac taaattttac aaaattaatc aatactatat tttaatatac aataaattta
    19381 ttttataaac tttatttact cttaatatac tttattgctt atttttttaa ttttttagat
    19441 gtttttataa acttttctcg attatacctc cacctactac aatatctcca tcatacatta
    19501 ctacagattg acctttagta atagctcttt gagcttcatc aaaaactatt ttaatagtat
    19561 cttctcctac tctatgaata gtagctggtg atggttttgc tgaatatctt attttggctt
    19621 gaactcttaa gggttcttct aacgtatcta ttgatataaa gttaacatct ttagcaataa
    19681 gttccttttt aaataaatct tcattgtctc caagaactat ggtattattt attggattta
    19741 tgtctattac aaacattggt tttccaaaag taattccaag cccttttctt tggcctatag
    19801 tataatataa tataccctta tgttttccaa gtatattgcc tttagtatct acaaaaaaac
    19861 cttcttcaat acgcttttta gaatgttttt ttacataatt tgcatagtca ttatctttaa
    19921 caaaacaaat ttcttgacta tcaggcttat tgtgtactgc catccccatt tccttagcaa
    19981 tttctcttac tctatctttt tcatagtcac ctattggcaa taaagtatgc tctagttgct
    20041 cttgtgtaag attataaagt gcataagttt ggtctttttt atctgtaaca gattttttta
    20101 gcaaatatct tcctgtactt tcatcctttt ctatctttgc atagtgacct gtagctacat
    20161 aatcacaacc tatttgtcta gccttcttat aaaaatcatc aaattttata tgtttattac
    20221 aagctataca gggattagga gtttttcctt ccaaatattc atctataaaa taatctatta
    20281 ctttttcttt aaacacttct ctaaaattta aaacataaaa tggtatacct attttatttg
    20341 ctacccttct agcatcttca acagcagata aagagcaaca accaccttca atttcaacaa
    20401 catcatcatc ttgccacaac ttcatagtaa caccaatgac atcatatcct tgttgtttta
    20461 aaagatatgc agctacagag ctatcaactc ctccactcat acctatcatt acttttttat
    20521 tcataaacaa atttcacctc atcttttgca ttacttatta ttataccata tagagcaagt
    20581 attgtactta tttaaaatat agcttgttct attttctaaa aaaataatca tctttattat
    20641 ttgaatctta tggattattt tgttaactaa ttaacctcta aatcaagtta aaatacttaa
    20701 tttaggcaat aaaaaatagc cattttaaaa acagctattt tttatgtcct aattatatca
    20761 ttagtacttc tttttaatca ttgtaaactt ctcataacac aatcacttat ttttattctt
    20821 cttcttcaac atcatggtca tgagcatcat ctataacata tccatccaat tctggtatat
    20881 ggatattgtt cttttgagca taatctataa gagctgcttt tacagcttgt tcagctaaaa
    20941 ctgaacaatg catctttact ggtggtaaac catccaaagc ttctgcaaca gctttatttg
    21001 taagttctaa tgcatctttt atagtttttc cttttatcat ttcagttgcc atagaagaac
    21061 ttgctatagc tgaaccacag ccaaatgttt taaacttaac atcctttatt acatctccat
    21121 ctatgtctaa aaatatcttc attatatctc cacatgtagg gtttccaact tcacctacac
    21181 cacttgcatt atcaatttct cccatatttc ttggattcat aaaatgttcc ataactttat
    21241 cactatattg cattatcttt tcctcctact caatttatgt ctatttttta tgctttatct
    21301 ttctgtctat tttactaaac cttgtttctt cgcatcatca taaagtggtg acatgcttct
    21361 aagtctttct attacttttg gtaagttctc tagtatataa tctatatcat catctgttgt
    21421 aaaatctcca actgtaagtc ttaatgaacc atgtgctatt tcatgtggta aacctattgc
    21481 aagaagtaca tgtgaagggt ctaatgaacc agaagtacat gcagaaccac ttgaaccagc
    21541 aattcctaac atatctaata ataaaagtat tccttcacct tctataaatt ggaatgcaaa
    21601 gtttgcattt cctggcaatc tattttctaa gctaccattt actcttgtgt aaggtattct
    21661 ttctaacaca ccatctatta acttatttct aagacgagtt aaagtttcta catgattttg
    21721 catattttcc ttagctaatt ctgctgcttt tccatatcca actattgcag gtatattttc
    21781 tgtaccagct cttttgcttt tttcttgtgc tccaccatgg acaaagttat gaagtcttac
    21841 accttttctt atgtataaag ctcctacacc ctttggtcca tatattttat gtgaagacat
    21901 actcatcaaa tctattccta attctttaac atctactgga atattacctg tagcttgtac
    21961 tgcatcagtg tggaataata tcttatgttt tttagctatt tcggatattt ctttaatagg
    22021 ctgtatagtt cctatttcat tatttgcaaa cattatgctt ataagtatag tagtatcttt
    22081 tattgaatct tctagttgtc ttaagtctac tcttccttcg ctatcaacat ctaaataagt
    22141 tatttcaaat ccatgatgtt ttgctaagta ttcacatgta tgaagtattg catggtgctc
    22201 tatttttgaa gttattatat gattaccttt gtttttatta gcataagcta caccctctag
    22261 tgtccagtta tcactttctg aaccacctgc tgtaaaatat atttcactag gttcagcatt
    22321 tataagggct gctacttgtt ctcttgcttt atccaaagca tcttttgctt ctcttccgaa
    22381 tgtgtgaaaa ctagatgcat taccaaaata atctgttagg tatggcatca ttgcatccaa
    22441 tacttctttt ttaataggtg ttgttgcaga ataatccata tacaatcttc ttttttccat
    22501 tacattcatc tccaaatcta ttttttaata tttgttatat cattttctaa tttatttttg
    22561 ttatagtcat ttatcatatc tttaagagta attgaatcta taacatcttc tatacccttt
    22621 ttcatctttt cccaaactat ttttgttaca cacatgtttg agttttcaca tacatcttca
    22681 tctagtacac agtcagataa tgcaactggt ccttctaata ctacaagtat atctcctact
    22741 gttatgtctt cagcattctt tgaaagcaaa taacctcctt gagcacctct cacacttttt
    22801 actagacccg atttttttaa agatgaaaat atttgttcta agtactgatc tgatattttt
    22861 tgcttcttag caataaattt taatgatact ggtccattgt cttgatttaa tgctaattca
    22921 aacattgctt ttagtccata tctaccttta gtagacaact tcatatatta tcacctctat
    22981 atagaaatct aattcatact gttttagtag gaattacttt caagataatt ttattatacc
    23041 ctactaattt tgtcaagatt aattttaatt ttttattttg aataaattcc ccattttcca
    23101 atgttttcaa atcctagttt tttatatatc tttccagcct cttcattatc ataaaacaaa
    23161 caaggaattt tgttttctct cagtaactct gaacatagtt taattaggca ttttgtagca
    23221 agtcctttag ctctatattt aggatgtgtt cctactccaa ttatcattgc atgagtccta
    23281 ttttctgaag tactctttgc cattgacacc acctgtttgt taatctctat acaatatcct
    23341 ctacctgtcc ttagtccatt ttttaaattc tctaaagttg tactgtgaaa ttcatctatt
    23401 aagtcataaa gtttcactgt cttttttaga tttccaagcc taattctctt aacctttgca
    23461 ttacaattat tatctatcaa aaacttttta gtttgaagtt tgcaaaaatc aactaccttt
    23521 aaattattaa gtcctaatct ctttgctaaa gtatctacag cacatatttt cccagatatt
    23581 tcttcgtaat tagtattacg aagtagatta taaaaacctt caacatcata ctctccatca
    23641 gaataaaaca tcataaattc aaaatattta agtaatattg cctttatttc accatgttca
    23701 cccacgtctg cccatatatt taaaaaatta tttccatatc catatctttc aatatcccct
    23761 attataaaca aattgtactc aggttctttt tttaagtatt tcataactct actgtgataa
    23821 gttgagttaa gttttataat cataatatct acccccgata cataaaattc agtctaaaaa
    23881 tcactattta gatattctaa atattttttt atatttttct cagttttatt ttcttgtggt
    23941 atgtaataaa tactatcttt tatgctatct ggtaaatact gttgctttac ataatgattt
    24001 ttaaaattat gaggatattt gtatccacaa cccctaccta tttctttaga accagaatag
    24061 tgagcatcct ttatactatt tggtatatcc ttaacaaact ctttatccag ttcatccata
    24121 gctttcatta ttgctataca tgcagaatta gactttggag atgtagccaa aagaatagta
    24181 gcttctgcta atggtatttt cgcttctgga aatccaagtt gcatagctga gtctacacat
    24241 gcctttacaa ttacaatagc atttggataa gctaaaccta tatcttcact agctattact
    24301 aaaagtctcc tacatatact tatcaaatcc ccacctttta taagtcttgc tagatagtgt
    24361 atagatgcct gtgggtcact tcctcttata gatttttgaa atgcacttaa aatatcataa
    24421 tgactatcac catttttgtc atagtttata attttattaa atgtagatgc ccttattaca
    24481 tctgaatcta tataagttat attatcctta tttggtttag ttgaatagac taccacttcc
    24541 aaaatattta aggctcttct catatctcca tcagaaagaa ttgctatatc ttcaatagca
    24601 ttattattgc actcaatatc catatagcta tcttcattta atacttcaac agctcttttc
    24661 agtccttttt ctatatcaag tttttctaaa ggtttaaatt caaatacagt agacctactt
    24721 aaaagagctt tatatacata atgatatgga ttttctgtag tgctagcaat caaagttata
    24781 ctcccatttt ccataaattc taatattgat tgttgctgtt ttttattaaa actttgtatt
    24841 tcatctatat ataataggac tccatttaca ttatttatac ttccaagctc tgatatcacc
    24901 ttttttatat cttctaaaga tgaattagta gcatttattt tatagaagct tttattgctt
    24961 ctttctgcta ttatttccgc tactgtagtt ttaccaacac caggaggacc aaaaaatatc
    25021 atatttggta aaaaattaga ttgtaatatc ttagacaata tttttccatt acctattata
    25081 tgactttgac ctattacatc attcattgtt tttggtctta ttttatctgc taaaggcatt
    25141 ttctcactcc tttttaatat acttatcatt accttaataa ttcgtctaaa aaaggtatct
    25201 atttgaaata gatacctttt ctaatctaaa cctataaaat atagattatt gattgttttt
    25261 taattttttt aattcatctg taagtttgtc attaagtatt cttatatgag tacctttcat
    25321 acctaatgat cttgattcta tcacacctgc actctcaaat tttctaagtg catttactat
    25381 tacagaccta gttataccaa ctctatcagc tatcttactt gctacaagta gaccttcttt
    25441 tccatccaat tcagcaaaaa tatgttcaac tgcttcaagc tcggagtagg acagagtgcc
    25501 tattgccatt tgaactacag ctttctttct catttcttct tctaattctt cacctattgc
    25561 tcttaatatt tcaagaccaa caacagttgc actgtattca gctattacta aatcatcatc
    25621 attgaatgaa tttgaatatc ttgaaagtac caatgttcct aatctttgac cgcttcctaa
    25681 tattggaact actgtagtat atttttgtaa tcttccatgt tcttcaggaa agatttctaa
    25741 tatcttctca ccatttaaat tttctaatgt ttcatcaatt tttaacacat tttgagtata
    25801 ttcatctgaa aatttctttt gcttagtata ctcatcttct ataactgaac tgtcttgaac
    25861 atcatttaaa tgaagaccta gtactttacc ttttgcactt actacataaa cattagaact
    25921 taaaacgtcg cccaatgctc cggccagtaa atcaaaagag acactgcttc caccacttgt
    25981 ttgtaatgtt ttatttattt tccttgtttt ttgtaacact tcacttgcca tttaatcatc
    26041 tcctcatgaa atttaggcct tttaataacc ttttatattt tctaatatta ttttcacatt
    26101 taatgaaaat ttatttttct attagttgtt tacacttgaa agattatcat agattggaac
    26161 ctttttcaag agaattatgt gatttttttc aattttcact cttttccgtc attatgctct
    26221 tttgtctctt tattacattc tttattagaa cacactgttt ttgtttcaga tttagtcact
    26281 ttttcaacca tatatgaacc acacttctca caaaactctc ctgttggctt attccaagct
    26341 acaaagtcac agtttggata attagaacac ccataaaaag ctttacctct tttagatttt
    26401 ctaagtataa tatctccttc ttcacatttt ggacatttaa caccaatttt attcataatt
    26461 ggtctagttg ttttacaatc gggatagttt ttacaagcca taaactttcc aaatctacca
    26521 tatttgataa ccatattaga cccacagttc tcgcaaatct catcagtttc ttcatccata
    26581 tttacttttt ctatattttc aagagcttct tcaatagcct ctttaagtgg tgcatatgat
    26641 tctgatacaa tctttttcca atctgtattg ccttcttcta taacatcaag tttactttcc
    26701 atatcagcag taaaatctac atctataaat ttatggaaat tattttccaa aatatcagta
    26761 actattattc caagttctgt tggacataga cttgttcctt gcttttcaac atactctcta
    26821 ttcagtatag tagctattgt tggagcatac gtacttggtc tacctatacc tagttcttct
    26881 agtgttttta ctaaactagc ttctgtatat cttgctggtg gttgtgtaaa atgttggtct
    26941 ggcaatatat tttctatatt taatatatct cctttttcta tacttggtaa aattttgtct
    27001 tctctttctg aaaaattata taccttggta taaccatcaa atttcatttt tgaaccagtt
    27061 gccttaaata caatatcgcc tattttacat tctacattta gtatatcaaa cactgaatct
    27121 tccatttgac tagctacaaa tcttctccaa attaaattgt ataacttgta ctggtctttg
    27181 ctcaatgagg cttttatact ctctggagtt ctatcaactg aggttggtct tattgcctca
    27241 tgggcatctt gaaccttttt agtatccttt ttttcttttt tatcaccagt gtttttatag
    27301 tagttttctc ctaaattgtt tacgatataa cccttagctt tttcttttgc ttcatcagat
    27361 attcttttag agtcagttct tatatatgat ataagaccaa cagtaccttc accttctatg
    27421 tcgatacctt catataattc ttgtgctatc atcattgttt ttttagtagt aaaaaataac
    27481 ttatttgctc cttcttgttg aagcatactt gttgtaaatg gttttggagc tgatttacgt
    27541 cttgatttag attctatctt ctcaaccttt aaatctttac cttccatttc ttttagtatt
    27601 tcatttacag cttcttcatt ttctaattca atcttttcat catttttacc ataaaatttc
    27661 aaagttatat ctttgtcttt tactgtctta gcctcaacat ctattgtcca gtattctttt
    27721 ggaataaatg cctttatttc tttttctcta tcacaaatta actttgttgt aacagattgc
    27781 actctacctg cactaagacc ttttctaacc ttttgccata atataggact tatttgataa
    27841 cctaaaagtc tgtctagcac tcttcttgcc tgttgtgcat caaccaaatt tatatcaata
    27901 tttctaggat gtttaattgc ttttttaatt gcatccttag ttatctcatt aaactctatt
    27961 ctacaatcct cagattcatc taaatttagt atatgagcta aatgccatga tatagcttca
    28021 ccttctctat cagggtcagt tgctagatat acttgtttag attttttagc ttcttttttt
    28081 aattctttta ttacatcgcc ttttcctctt atatttatat attgaggttc aaaattattt
    28141 tctatatcta cacctaattt acttttaggt aaatctctga catgaccaac tgatgcttta
    28201 actgtgtaat gacttttccc taaaaatttt tctatagttt tagcttttgc aggcgattct
    28261 acgatgacta atgttttggc cataaaacca tacaccccca ctacctaatc ttaatttata
    28321 catttaaact gtacgtttta ttattcattt ctactactaa ctcatttagt actaattcat
    28381 tgattattga atttacatac tttatttcta taccagtata atcacaaata ctatctatat
    28441 gcaagtttcc ttctcttttt atagcttcaa ttatttgctt agacttggca tttagactta
    28501 tattatcata tttttgattt atttttttat caataatatt aaatatgtta tattcattta
    28561 aaatatcatc tatattttca attaattttg caccttcttt tataatttta tgacaacctc
    28621 tactcatttg agaatttata ttaccaggta ttgcaaaaac attttttcca tgttcaagag
    28681 caaaatctac tgtgattagt gcaccacttt ttattgctgc ttctacaaca actactccat
    28741 cacttaaacc actgataatt ctatttctat tagaaaaatg gtacggggct actgtcgagt
    28801 taatattata ctctgataat aataatcccc cattttctaa tattttattt gataaatgta
    28861 aattttgttt tggaagagga ttgtctactc ctgaaccaag tactgctata gttttagatt
    28921 ttccactcat acaacctatg tgcgagtatg catctattcc tatagctaat ccacttacta
    28981 tattaactcc atattgggat agttgacaac ttattgtttt tgcacaatta attccatagg
    29041 ctgtaggttt tcttgaacct actatagcta tattaaaatt attattaact aaacctatgt
    29101 cacctttgta gaataataac tttggagcgt tgtatatatt ctttaaattt tcaggatatt
    29161 ctttatcata tttacaaata tatttaatcg cttttttgta aagtagttct tttatatttt
    29221 ctaaataagc gtaacctcta tattttacta tattttttct aatattcaag cttatatttt
    29281 ttaaattata tatttctttt tcagaaaaat caaatatatc ttcaatattt actatttcat
    29341 tttctattat ttcaattgtt tttgttgtta ttccaccaat tgattttaac cataaataag
    29401 tatctctttt ttccataaaa tccacctcaa aaaactattt aaaataacta taataagcct
    29461 ttctaaatga aaaagcttct ataatacact gtgaatttat caagtctctt tcttctaaat
    29521 ctgctattgt tcttgccatt tttaaaagtt ttgtataact tctactgctt aggttgtatt
    29581 tattaaatat catctcagcc gtttttgaag cttctttttc cagtttacaa tatttaaata
    29641 aattgtaagc tttaatttca ctattatttt ttatattatc tttcttaaat ctatttatct
    29701 gtatttttct agcattttct actcttctct ttattttttg agagctttct tcttgtttta
    29761 aagaattaaa atctgaatat tttatagaat taacttctac aaaaatatca aacctatcta
    29821 acaatggacc tgatatttta tttatgtatc tatcaatttc gttacttcta catctacact
    29881 ctgtctctga catataataa ccacatggac atggattcat agctgcaact aacagtactc
    29941 tacaaggata ttttgcactg tactttactc tggatatatt tacatatcca tcttctatag
    30001 gttgtcttaa agtctcaagt atttttctat caaattcggc tatctcatct aaaaataaga
    30061 tacctctatg tgctaaagca atttctccag gtcttgcatc cattcctcct ccaattaaag
    30121 attgctttgt agttgtatga tgaggtgctc taaaaggtct tttatcaatt attcctttac
    30181 tttcatttat catacccaat atactataaa ccttacttac ttctatcatt tcttctatac
    30241 ttatatctgg taaaattgtc cttactcttt ttgcaatcat agtttttcct gagcctggag
    30301 gtccaatcat aaacatatta tgatttccag ctgctgcaat ttctgcactc ctctttacaa
    30361 aataatttcc ttttacatct ttaaagtctt catcatattt actttcttca ttattaatct
    30421 tagtatattt gcaatctata taactattat ctttttctaa ttctccgttc tcttttcttg
    30481 acttatcatc caaaaaagac attatactta ctttatcgac ttttatctct tcgtttaaaa
    30541 aatcgacaca ttcttttaaa cttttaatag gaattatatc aatttcatct actaatagac
    30601 tttcttttat gttctcaatt ggtataaaaa tacgttttat gttctgagtt tttgcaccca
    30661 taattatggg caatatccct cttacttttc ttatttttcc atctaatgat aattctccta
    30721 taaacatact ttctcttatg taattttcat ctttttttat taactctctt aaaaggccta
    30781 tacttataga taaatctaaa aaagctcctt ctttttttat atctgctggt gataaattta
    30841 caactattct cgtgcttgga aatttatatc cactattaag aattgctgac tttactcttt
    30901 ctcttgcttc tttaatttct ttgcctggaa gaccaacaat attaaaacta ggtattccat
    30961 tgcttacatc tacttcaacc ttaactaaaa agctgtcgat tcctactaag ttgcttgaat
    31021 taataatact taacatattt aatcctttcc aaaaacatta tcttttttaa aaagcattca
    31081 ttatgtgatt tattcttttt tctaacaaat agacctctat gatgtcaaat cttatgggag
    31141 tattatttaa gttatttttt ataatatagt attttgcgac accaattatc ttttttcttt
    31201 ttttaaaatc tacagattca caagggtagc catactttat gttagacctt gatttcacct
    31261 ccacaaatac aacttcatct cctatatttg ctattatatc tacctcccct atccttaatc
    31321 tataattttt ttctagtatc tttgcacctt ttgatagcag ataattaact gctatttctt
    31381 ctccaaaatc acctttttct ttattattca ttatctactc caatatatta aatttttact
    31441 tttaaattat cgtcagtata caatttaact attcaatttt ttgaaattga ttttatttcc
    31501 attgatatta ataaatactt ctattgactt tattctttta tgatattatg ctagttttta
    31561 taatgaaagt ttatttttat ggaggaatgt ctttaatgaa cagaaaaaaa acatttattt
    31621 ttatacgata tttatctcta tttatattac ttataagtta tttaaaccat actgaaaata
    31681 cattgtatcc agctataaca atgattatat tatttctaat aataaataat caagttagat
    31741 ttttttcttt atcaagtgag aataaattta tacttatttc ttatttttta gagcttattc
    31801 taatttttat attttgtaag tatataaaga cttttaatcc actttactat gtttctttaa
    31861 ttttggatgc ctcattttta ataaaggaaa aatataaata tatattattc tctttagtta
    31921 taatattttc ttttattatt ggtttagata aaaatttata tttagcacta gaatcaagtt
    31981 ctacattact aattataacc ctcttttctg tgtatctaga aaacgagaat ttatctaaat
    32041 tatacaatca aagtctttat gacaaactca gggtttctaa agatgaatta aaaaaagcta
    32101 atgccgattt agagatttat gcaaattcta tagaagagtt agcaattttg aaagaaagaa
    32161 accgtatatc gagggaaata cacgatagtg tgggacattc tctttctacg acgataatcc
    32221 aattaaatgc tatagaaaaa ctcttaaaag acaaacctct catttctgat ttagttcatg
    32281 aacttagaga gtttgtaact gaaagttttc aagatgtgag aagagctata tctgaactaa
    32341 aacccattga atatgaaaat taccaaaatt tacttaaaat cagagaactg gttaatagct
    32401 ttattaaact tacaaatatc aacgttagat taactatatc aaaaaatacc tggaacctat
    32461 ctacaaatca atctatcgct ttatatagac ttgttcagga atctctttcc aacgcatcaa
    32521 gacatggaaa agcaactgaa atcagaattt ttataacatt taatccttca aatcttataa
    32581 ttactatcag cgataatggt atagggtgta acaatataaa aagaggaaat ggacttagca
    32641 gtattagcga aagaatatat gaattaaatg gtaaagttga attcgataat tctaatactg
    32701 gattcacaat tagagcgtct tttcctaaat tttcaggagg tgattttttt gaataaaatc
    32761 aaagttctta tagtagatga tgaaaaattg attagaaaag gtcttaacat tattttatca
    32821 tcttatgacg atttagaaat tgtaggagat gcttccaatg gatatgaagc attagaattt
    32881 tgtaaaacaa atgatgtaga catagttctt atggatattc ggatgaaagt ttgtgatgga
    32941 gttctaggca caagacttat aaaagaatat gatagctcta tagcattatt aattttgaca
    33001 acctttaatg atgatgagta catagaagat gctatgaaat ttggggcttc aggatatctt
    33061 ttaaaggata gttcggatga agtattacat gaagggattc gttcctcgtt ttttggaaat
    33121 attgtacttg ataaaagtgt ggctgaaaaa attatgtacc ctcaaaaaac tatagaacaa
    33181 aaacatattt ctgatatgta taatttaaca gaaaaagaaa tatccataat tagattaatc
    33241 gcaaatggac ttaacaacaa agaaatcagc caagaattat tcttatctga aggtacaata
    33301 aagaataata tcaccaatat cttagggaaa ctagagcttc gtgataggac acaactagtt
    33361 atatttgcct tcaaaaataa aattgtaata taaatatata ggtaagaaat ctatacccta
    33421 gaaatttctt actcacaaac tcatttataa taaatgaaaa tataaagtga cttaagtcac
    33481 tttttttagt gacttatagt aatagaatta tgattcataa ttctttatta tagtattata
    33541 gatttttaac ttatacaaaa ttattttggg aggaattatt atggatatag taagagtaaa
    33601 taatataaca aaaagattta atgataaatt agcacttgat aatatcagct tttctgttaa
    33661 agaaggagag atatttggac ttattggacc gaatggtgct ggtaaatcta cacttataaa
    33721 tataattaca aatcttatgt taccaaatag tggcgacatc caaatcaatg gtttagattt
    33781 gtcaaaagat tgtataaaag caaagtctat aataggatta gttccacaag aattagcact
    33841 tatagagact cttactcctt ttgataactt agagtacttt ggcacttact atggactaaa
    33901 gggaaaattg cttcaagaga gaataactga agccttagaa gtcacaggac tcactgatgt
    33961 taaaaagaaa aaaatcaaaa aattatctgg tggtatgcaa aggagattga acattggaat
    34021 agcactttta aatcatccta aaatattaat attggatgaa ccaactgtag gtgttgaccc
    34081 gcaatcaaga aaccatattt tcaattttat aaaaaatata tctaaaaagc aaaaaaccac
    34141 agtaatatat acttctcatt atatggaaga agttgagcat ctttgttcta agatttttat
    34201 tatggatgaa ggtaaagaga ttgcttttgg agataatgat tatttaaaat cattagtatc
    34261 tacaaataca aaattaatta tggaaataaa aaatataaat gctcaactta tatttgattt
    34321 aaaaaatact aaaggtgttg tatctatttt agaaaataat tcattattag aattaggtgt
    34381 agacaaaaaa ttacaactta cagatgtatt atctgttgtt gacaaaaata attcaaaaat
    34441 aacacgaata tcttatgaag aacctagttt agaagacgta tttttaaatc taacaggtaa
    34501 aaatttaagg gactaatgga ggtgatttca tgaaattgta cattagtgta aaaactatgc
    34561 taaaagtttt aaaaagctcc tttatgctta atttaatata tttcttagcc ttacctctag
    34621 ttttagctgg atttcttggg atggtgacag aaagtatatt tcaaaatcct ataaaaacag
    34681 atttgacatc aattgttata tatgataaag ataatacaaa gctatcaagt aatttgacag
    34741 gatatctaaa aaacgattta tcttctatat taacagttca aaaagatgat tctaaggcag
    34801 acttaaaact tactatacct aaaggatatg agaataattt attaaatgaa aaatcaaata
    34861 atctaagtat agaaaaactt aaatctaatg ataatattgc aatattactt caagatatat
    34921 tagatactta tcatgaaaaa ttatatctga ataattctca aaaattaagt tcagaagatt
    34981 tctcaaaatt atttaataag aattctattg atacctctat aataaaaaat aatgttaaac
    35041 aaaactctta tgagtacttt gctttagttt cccttggatt cttcgcaata atttttataa
    35101 tgaatagcat tttatcaaat tatgtaagtg aatcaaaagg actttcaaaa agactctact
    35161 ctatacctgt aactagagta caatttttaa tttatgattt tataggtttc tggatttact
    35221 catttatatt tttatcatta tacgttttat tttttagaac actcggtgta acattcaaag
    35281 gtaactttgt tatattagct ttactttgtg ctttagcttc ttattttatg acttcaatat
    35341 ctacttttat aactaccttt tttagcaaga aatatggtac agttatagtt tatgcattac
    35401 tcttcttgca aacagttttt ggaggtattt tcagcatagt aaatgatgtg tttactaagt
    35461 ttacaagttt atctcctact tatttaatag gaacattgtt cagtaattat gagacgttta
    35521 aaactataga ttcaatagaa agtttaattt ttacatgcct aattgcatct acagtattga
    35581 ttgcactttc tattgtaaaa gaaaaatata aatggaggga ggtttaataa tgattaggtt
    35641 gactattgca aacataaaaa gatatataaa aaatcatgct cttttagtta atatggtttt
    35701 gtttcctgtt atattaatgt tttatcttaa cttttttact ggcaactcag aaaatcaatc
    35761 aatgtacttt tctccagtag cgattgtatc caattcttct ggaaaatacg aacataagtt
    35821 aatagatagt tctaaattaa aagaaaactc atttggatta aacgaacaag acaaggctat
    35881 ggatctatta aaaaataata aagtttctgc tgtcttcatt ttagataaaa acttttcaag
    35941 caatatagat aacttaaaac gacctgaggt taaatgtttt aaaactgaaa atggtggagg
    36001 tagtctttgg gcagaatcac aaatagaatc ttttattact aattcattaa aattaaaaat
    36061 agatagaaat atagatgata aattgaccaa gacaaatata attgataaca gttcaggtaa
    36121 gaataaaaat tcatttttaa tagttttctt gatatgttat ttcatgtaca ttaatgcagc
    36181 acatctagct tctgatttat tttcattaaa gaaatctaat accttaaaaa gacttgtttc
    36241 tacaaagcat aatgatataa aaataatttt cagcatattt ttagggttat tttttactca
    36301 agcaattgta tacaccttaa ctttagtatg tttcacatct ataagtaatt ttaaattgac
    36361 tctaaataca ttgatgattg tactagcaaa tagttttgtt gctactggat ttgtattttg
    36421 gatagctagg gtgtttaaaa acgaaggttc tataagtctt atgtctacgt tttattcttt
    36481 aataggttta gctatatcca tatctaatat gataccatca cttgataaat tatcctttat
    36541 ggctaatctt tcaaagctta caccatttta ttggactata gatgctatta ataataatgg
    36601 taatatatta ataaatataa ttgttttaat tcttattgga atggtatttg taacagccgg
    36661 aagtcttaac ttaagagatt ttgctagaaa ttaataatta ttaaatctag ttagtatgtt
    36721 attttataca atactaacta gatattttaa tatattaaat cctcttatct tatattttta
    36781 tagccaatta tatatatcta ttattctaaa ctttttatta tatattaatc tttttgactt
    36841 gtcaagcatt tcgtgatata atattaatta ttagataatt aaagcattgt acccaaattg
    36901 caatatctaa aattcagttt ggaggtataa ccatatgtat aaaatcggtg aaagtgtaat
    36961 gtatccaaaa gaaggagcct gttatataag tggtcttgta acaaaggata taaatcatca
    37021 tatacagaaa tactatgaat tgactgttat ttacaatagt aatcttaaaa tttcgattcc
    37081 agttttaaat gctgataaga ttggtgtacg tccaattatg gatgaaaatg aagttgaaaa
    37141 ctttatccaa tcccttgata aggttgattg tttatgggtt tttgatagaa aaaaacgact
    37201 taaactatac catgataaat ttcattcagg agatgttttt gagattgtaa aattaattaa
    37261 gatgcttatg atacaagata attcaaaaca actatgtagc acagataagg actttctaaa
    37321 taaggctcaa aggtttgctt tgtcagaatt ggctgcagca caatgcaaat cctacacaat
    37381 tgtattagaa gaaatgaaaa accatatact aaattcaaaa aataacaatt aaattggtct
    37441 tatagactag tttaattgtt taactattca tacaattact ctatttttct tcaaaccttt
    37501 taatctaaca ttgataaaga tagattaatt atatagacat ctttatttaa ataaaaaaat
    37561 ctaggggtaa atcatattct tgattttccc tagatttagt aataaaactt actcttcctc
    37621 aagttctttt ttctcttcca gtaaaacacc taattcgttt gcttctaaaa cttgtgcctc
    37681 tgcaatatca agtaactctt gttgccattc cacacattta tctttgtaat caaaaggtag
    37741 cgttctgtca actatgtact tatcaataca gtcctccgca cttttaatta tttcttttct
    37801 ttcatcaata aatttttcta attctactaa ggcttcttca taagcttttc tactcatata
    37861 aattccccct ttgtacaatt attctacatt aaaatgattt ttcctctttt ttgtataaaa
    37921 ttttatttgt atataacttt tccatcaata tcttttatag tttgacatcc agttaatatc
    37981 atagaactac ttagctctga ttgaagttta tttacataag tttctacacc atcagttgca
    38041 ccaccaaatg aagcagtcac aaaaggtctt cctattaata ctgcatctgc acctaaacct
    38101 atcattttta gtacgtctaa accagttctc actccaccat ctgcaagtat tgtaacttta
    38161 cctttaacag catcagcaat ttttggtaaa acttcacatg ctcctggtgt acagtcaagc
    38221 actcttcctc catgatttga tacaactatt gcatacacac ctgcttctac tgccattaaa
    38281 gcatcttcaa cagtcattat acctttcaat ataaatggta gtttagtaga ctttactaac
    38341 tcctttattt gtttaacatt tttaggaagt actggttttc catgtaatga taaagttact
    38401 agaccacagg catctatatc aactccaact gcaaatgcac cagcttcttc agctaatctt
    38461 atctttttta taatattttc attatcccaa ggtttaataa atacaattcc agctccatta
    38521 tactttttga ctacatctaa attttccatt aaaaaagcat ctactgccgt atcaccaacc
    38581 attgcataaa taccactatt agcacatcct gcaactactg gttctatgta atctctttca
    38641 ttaatttttc cacccatatt taaagtagtt cctgttactg gagctgcaaa tataggtgca
    38701 ctcattttct ttccaaacat ctctatagat gtatcaggat ttgatacatc atgtattact
    38761 ctcatattta cttttacttt ttctaaactc ttgctatttt ctataaaaga agaaccactt
    38821 cctttacctc ccatgccagg cacttcacct gcacaagcaa ccccattaca aaccttacaa
    38881 actttacaac ttccatttaa attttctcta gcacttttta ataattcatt atattccatc
    38941 tttaatcccc cattaactat agtaatttat attatataca ttatatcata ttatatttac
    39001 agtatatttt tcaaaaaact ttttctgtgg ataggagtta tgccatattt ttcaatagct
    39061 tcatagtgtt ctttagttcc atatcctttg tgagatttaa acccatattc tgggtatact
    39121 ctatcatatt ggtacattat actatcccta gtaactttag caagtatact tgctgctgct
    39181 attgatatag attttgaatc tcctttcaca attggatttt gagatatgtc aatacctggt
    39241 attgttgctg catcaactaa taaataatcc ggtgcttttt ttaaacaatt tatagccttt
    39301 ttcattgcca tatatgtagc atttaatata ttaaattcat ctatttcttc attatttact
    39361 atacctattc cataatctag tgcttcttct tttattactt caaaaagttc atctcttttt
    39421 gcctcactca gtttcttaga gtcatttaca ccttctattt ttgtatcttt tttaaatact
    39481 acaacagaag ctacaacagg tccagcaagt ggccctcttc ccgcctcatc aattcctcca
    39541 atatacaaat aacctttatc atagccttcg ttctcaaata tatttatagt ttccaatctt
    39601 tcttcttctt ttctaatatt atccagcttt tttgctagtt ttatagctag accttgtaca
    39661 gattttcttt catcaactct taacagttct atatattcca tatatttttc tacttctaaa
    39721 gtctctatta tttctttaat ctccctcaca cttttatcct gcataccatt ccctcatctt
    39781 tcgtttttaa aaatttaatt tttaaatata ttaaaatttt ttaattagag tttaattgca
    39841 tccactatag ccacatttta aacatatact acatccacct gtatgtgcaa ttccttcact
    39901 tccacattca gggcacacaa atttttcatc ttcttcaaaa tttttattta ttatttcttt
    39961 ggctttttca tctttattat ctttttcttt tttattattt ttataatatt cttttttact
    40021 attttctttt ttatcttctt tattattttc ttcctttttt tcatttatta aaattccact
    40081 ccttttacat ccatctctaa atattgttac tcctttaaga ccagcctccc atgccttaat
    40141 atatatattg aaaacatctt caactgtagt ttcaaaaggt atatttattg tagatgatat
    40201 agaagcatca atatactttt gccatacttt ttgcatgttt attctttctt catatcctat
    40261 attcatagca gtaacaaaaa aatctggtaa acattcttca tctgtaatac ctttcttgtc
    40321 catatactct ttaacaattg gagtatatac tttataatac acatcctcat catgcaagct
    40381 ttcagttttt cttatatatg aaagattaaa tataggttct attccaccac tgatacctat
    40441 cattgtagat atagaacctg taggaggtat ggttaaaagt tgtgaatttc taagcccata
    40501 ctttttaacc atttctttag tgtcttcatt tagattttct ataaaaaact tagatttaga
    40561 aatattttca tatttatact cactaaatgt tccatattct ttagcaatta atgctgattg
    40621 cttcacagct tcatttaaca tagtcttacc aattaaatca catagttcta aagattcatc
    40681 agaaccatat cttattccca tttttataag catatcagct atacccatta cacctaaacc
    40741 tatctgtcta tacttatgta cactatctct ttgttcttgt aatggatgca agttcaaccc
    40801 ctcatctaag acatcattta aagctactac agcttctcta acgcaagatt ttaatttatt
    40861 aatatcaaaa gtagcatgtt caccaaatgg ttgtattata aactctgaca agtttattga
    40921 gccaagtaga caacttcctc cacttggaag tggttcttct gcacaaggat ttactcctga
    40981 aaagcaaaag ttcttatctt cactcataaa attatatgtt tttattttat cccaaaacaa
    41041 tatacctggt tctgcataat cccagttatt tttcacaaat ttattaaata aatcataagc
    41101 atttactatc ttaactattt tttctccagt agtttcaact tcaaaagtac aattatataa
    41161 ctttttttcc cttacagctt gcataaattc atctgttacc cttatggaaa tatttgcttt
    41221 agtaaccttc tccaaatctg tttttatatc tataaactct tctatctccg gatgatttac
    41281 atccatagaa atcataagag ctcctcttct ccctctttga ccaattaagc cagttgtcat
    41341 actgtaaagt tccataaaag agactgctcc agtcgtatgt tttgcagcat tgttaacttt
    41401 cgctcctttt ggtcttagct ttgaaatatc aattccaact cctccaccat aactaaaagt
    41461 tctagcaagt ttttttgcag tatcaaatat atcttctatg ctatcttttg gtggttctat
    41521 tacataacaa ttagaatatg ttactttttt tccttctttc tgtaatcctc tatttgctaa
    41581 aattcttcca gcaaatagaa atcttttttg tcttattagt tttgatattc ttgaactatt
    41641 atttgaaatt ctctttatcc attcatcaaa actctcacca ttatgtctat acttgttctt
    41701 ccatattgat ttttgtaatt catcaaactc ccaagcttta gtccttattt cagagcgtct
    41761 ttctctatat aatatgtagt gttttgctat atcttttcta tttgattcca taagtagtac
    41821 ttcaactata tcttgtattt cttctacgga taagcatttt tccatagaat tatagtcatt
    41881 agctattttt cttgatatat catatgccaa ctctctatct actccacctt cactatttat
    41941 actagcttta tagacagcat cttcaatctt acttttacta aaaagttctt ttgtaccatc
    42001 tctttttatt atgtatttca tttttaaacc tccaataaat tagtattaaa ttaatacaca
    42061 cattaactat aactctaaac aaactttttt atatatttgt atattttcat attaattatc
    42121 taacataata tatattatac tatttta
//
LOCUS       DAMJYN010000032        41982 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.033, whole genome shotgun sequence.
ACCESSION   DAMJYN010000032 DAMJYN010000000
VERSION     DAMJYN010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 41982)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41982)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41982
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.033"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(183..1148)
                     /locus_tag="PC466_001775"
     CDS             complement(183..1148)
                     /locus_tag="PC466_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HDF2769162.1"
                     /translation="MNKKAAIVAAVAIIGLVTVFALGGSKKNESKTSENSNNTIKITH
                     NLGETDVKLNPKKVVVFDYSALDTMDALGVAENLVGLPKTSLPASLEKYKDKKYADLG
                     GLKEPDLEGIKSANPDLIIINGRQEDFYEQLSKIAPTISTSKDDKKYLESVKNNIDKI
                     AKIFGVEEKANQEFSKIEKKIETLNKKVTDKNLNALTIMVNEGNLSVFGEESRFSILY
                     NSFGFENKDKNIKESSHGQNITFEYIAKQNPEVMFVIDRGIATGSDVKESSTAKSVLN
                     NDIIKSMDAYKNDNIIYLDSPTWYVNDGGLTSLNKMIDDASKAVN"
     gene            complement(1240..1995)
                     /locus_tag="PC466_001776"
     CDS             complement(1240..1995)
                     /locus_tag="PC466_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF2769163.1"
                     /translation="MIEIKNIFKRYKNKNVVDDVSFSIEKGKITSFIGPNGAGKSTVL
                     SIVTRLIGGDGGEVIIEGKSLTNYSNKELAKKIAILKQSNNITLKLTIRELVGFGRFP
                     YSEGNLTKEDENYIDEAIEYMKLTDIQHKYLDELSGGQRQRAYIAMVIAQDTEYILLD
                     EPLNNLDMNHSVQMMKVLRSLCDELDKTIVLVMHDINFASCYSDNIVALKNGKVEKVG
                     RTDEIVNEKVLEDIYEMNFNIKNINGNRICIYF"
     gene            complement(1992..2948)
                     /locus_tag="PC466_001777"
     CDS             complement(1992..2948)
                     /locus_tag="PC466_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HDF2769164.1"
                     /translation="MKLSLNQKIYFVSILLFISIALFIIYGIDMNHLEYALSQRIPKI
                     FAMVLGGGCIAFTTVVFQTITNNQILTPSVLGLDSLYVMIQTIIVFIFGSSSSLIINE
                     NYNFIINVAMMIGASLLLYKMLFEKNKNNIFFLILVGMIFGTLFKSATTFIQVMIDPN
                     EFLALQTSIMASLNNINTNVLLIAFIIIIAIIPFIYDEIKYLDVLSLGKEQAINLGVD
                     FDKAVKKMIILIAILVSISTALIGPMTFLGLLLANITREIFKTYKHTYLISGSMLIGM
                     ITLIIGQFFIQHVFKFDTTLSVVINFIGGIYFIQLLLKGANR"
     gene            complement(2938..3891)
                     /locus_tag="PC466_001778"
     CDS             complement(2938..3891)
                     /locus_tag="PC466_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HDF2769165.1"
                     /translation="MKKRYLVIGIIILSYFSLFIGAEDINIMHIFAKNQHKLMIFIMS
                     RVPRLISILIAGVGMSIAGLIMQQISKNKFVSPTTGATIDAAQFGIVICMLLVPTASI
                     FTKTIIAFVFSLVGTFTFMKIIGKLQFKNIIFVPLVGIMFGNIIGSMTDFIAYKYDLS
                     QNVSSWMQGDFSMILKGNYEILYITIPLIILAYIYANKFTVVGMGMDFATNLGLSYKR
                     IVNIGLIIVALVTVCVVVTAGNIPFIGLIVPNIVSLYMGDNIRASIWYTGLLGAVFVL
                     ICDIFGRIIIYPYEISIGLTVGVIGSILFLYLILRRNVNEA"
     gene            complement(4138..5118)
                     /locus_tag="PC466_001779"
     CDS             complement(4138..5118)
                     /locus_tag="PC466_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HDF2769166.1"
                     /translation="MIFDGHSDTWADVTIRRLNGEKDVFRRIHLDNFKRANIEGAIFV
                     IWIDPPYDKEPEKRVKQIISSIKDEIEDMKDVVNIVKKYSDIDKGISENKINILIGLE
                     GLSHIGRNIDLLDYFYKEVGARHASLTWNEQNELATGCLGDENRGLTEIGKKAVNKME
                     KLGMIVDVSHLNEKSFWDLMSVASKPVIASHSNARSLCDAKRNLTDNQLKEISNTGGL
                     VGINSFRGFTNSNPKKQDLIHLVDHIDYMVNLIGIEHVSFGFDFSDYLGKETIGSFTG
                     NASVPSVDGLESTHTAQNIVVELENRGYKKKDIELISSGNFYRLFKDILK"
     gene            complement(5175..6377)
                     /locus_tag="PC466_001780"
     CDS             complement(5175..6377)
                     /locus_tag="PC466_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF819 domain-containing protein"
                     /protein_id="HDF2769167.1"
                     /translation="MKSFVSPDNIWVLWAVVTGWAAFSIYLEQKYNWASKVSGAIIAL
                     VGAMLLSNLNIIPVESVVYDQVWGYVVPLAIALLLYQCNIKKIWKESGRLLIIFLVGS
                     VGTVLGAMIGFLALKNVVPDLNIVAAMMTGSYIGGNVNFAAMSGAFDAPGELVSATVV
                     ADNLLMALYFFVLIAIPSIGFFRKHFKHPHVDEMESIGITEGETVAANYWGRKEISLK
                     DIAIAIGSAFIIVAVSVELSTWFKAIIPLSNPFLAMLNTLFGNQYLIITTLTMLFATF
                     MPNFFGDIKGAQELGTFLIYIFFVVVGVPASITLIIQKSPLLLLYCGIMVLINMLVTF
                     IVAKIFKFSLEEAILASNANIGGPTTAAAMAISKGWSKLVGPILIVGTFGYIVGNYFG
                     LLVGNILI"
     gene            6572..7126
                     /locus_tag="PC466_001781"
     CDS             6572..7126
                     /locus_tag="PC466_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HDF2769168.1"
                     /translation="MNIDVGSKIRSLRKSKNISISTLAKNSDLSTGLISQIERNMVVP
                     SIVAMWKISKALDINIGYFFEEIGREDSDIVVKKNNRKKIVTNDSTKFYELLVPNLSG
                     KKIEFILVTLDGHTQKNSEFVTHEGEECGYIIKGKMKITLGNKEYLLEEGDSFYFNST
                     IPHVYENYDDEVCISVWAMTPPSF"
     gene            complement(7241..8032)
                     /locus_tag="PC466_001782"
     CDS             complement(7241..8032)
                     /locus_tag="PC466_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HDF2769169.1"
                     /translation="MIVFSDLDRSIIYSNKFLNADSKYANIEIYREKEISYISLDTIN
                     LIKQIQYYGMFIPTTTRTVEQFKRIEFNKYGIYFPWSITSNGGVILKDNEILKSWSEK
                     IDKLKPDYEPIESMIHKFKDYLNVDGITNFKVAEDTFFYIVVDFSRFNLDSIKEYTNI
                     LESKNWKFYVSGRKIYFIPKEISKENAIKYLTKELGIEYFYAVGDSIMDYGMLNISNK
                     SYVLKHGDINKNEIENSFISSSFKGMSGTEEILSNILDENCLLNI"
     gene            complement(8060..9148)
                     /locus_tag="PC466_001783"
     CDS             complement(8060..9148)
                     /locus_tag="PC466_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine protease StiP family protein"
                     /protein_id="HDF2769170.1"
                     /translation="MRDFSTYSKDDVIFLLKDISNLIEEEGNKERELKIQNGRHYSEM
                     IPIEYEVSEDYLNLYHEKLRENKDKLAFSIGVMCEKIIKKNGNDVVLVSLARAGTPIG
                     ILAKRYIRSKYNVSLPHYTISIIRDKGIDMNAIEYIVKNHPSSKIQFLDGWTGKGTIS
                     KELEKACDELNVKFKKHFDSTLAVLADPAGYSGLYGIREDFLIPSACLNSTVSGLVSR
                     TVLREDLIGKNDFHGAKFYRHLKDKDESMNYIETIEECFKNQFKNISDEVENWESDII
                     TRDGYFDVLNIKEKYNITDINFIKPGVGETTRVLLRRVPYKILVKDLNDKSLDHIFIL
                     AKEKNVEVEQMDLKAYKCCGIIKNMKDI"
     gene            complement(9202..10440)
                     /locus_tag="PC466_001784"
     CDS             complement(9202..10440)
                     /locus_tag="PC466_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosyltransferase family protein"
                     /protein_id="HDF2769171.1"
                     /translation="MKNCLNFNCEIDIIDNPLNLELNDFLDVGVRNNSKRRFLFISKK
                     LGKHLACKPSEMDNLGKLMATIYNEKNKEESNGTVIAFAETGTAVGHSFFDYLCGDYE
                     FIHTTREQFDELENLEFLEEHSHATDQNLYFGMLNNFKFGDEIILVDDEITTANTCMN
                     IIRKIQSIYPKKKYTICSILNWVSDENLSKVTRLERELNCKIDFVYLFKGNFKFYIDE
                     DIISNYNDNYSITKLETISSDKVNLVVNHIYVDLEDYIGNKKYVKYTGRFGINRREQF
                     RLKEIVKRESKKITMASKESLKNEKEKILFLGTEEFMYIPMLFAKEKENQYDIYYHST
                     TRSPIINIDKKHYPIKSKFMLKSFYNIDIQNYIYNIDKHNFSKCYLFVELNKSENSYL
                     EFIDIIKKTSIKELTIVCCS"
     gene            complement(10418..11494)
                     /locus_tag="PC466_001785"
     CDS             complement(10418..11494)
                     /locus_tag="PC466_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HpcH/HpaI aldolase/citrate lyase family protein"
                     /protein_id="HDF2769172.1"
                     /translation="MKYFDYICKDDLERIFLKEPEDFSAKTEKDVLKYALGAFLYVPA
                     TQYNMIYKSIIGDVKGVRPLAICLEDAVGVNGELEAIENLRLILKNISNESITNKDGI
                     PLIFVRIKDVEQLLRIKEIIIKNSHSITGILIPKANSELIENCIEALYSMNLQDMYVI
                     PIIETREFIYNEKKELSFTNLYNAILRHKSRILSIRVGITDILGMYGIRRDKNFSIYN
                     NLICSSFILDIITYLQRPELDIPISGGVSEFFDMTNKDIRNKYIEEILLDKYHGLIGK
                     TVIHPMQIQIVQALSTVSYEDFTDALDILDSTDSKYGVSKGVLGERMNETNPHFLWAK
                     KTLILSKIYGVLNKGVDYEELLKF"
     gene            complement(11558..12694)
                     /locus_tag="PC466_001786"
     CDS             complement(11558..12694)
                     /locus_tag="PC466_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HDF2769173.1"
                     /translation="MGININSFSKDKNSVEVTENLPTAVQEENFDIMEYTNNKKNELR
                     KSKEVEALTSLIEVENPDTILQFGRKASEGVARVSDSLLNTIKLNRNEENSKMLVHLT
                     KIMDKFDLDDFQETKEPNFVQKLFKKANNAIEMMFQKYETLGGEVEKIQIELEQYERD
                     IALSNKQIGAMLNENFEFYNELQKYIVAGEMAIEEMDNEILPFFKQKSETSGDQMDVV
                     NYQELLKVYDMLNQRVYDLRIAENIAIQTIPMLRGMQHNNYGLIRKINSAFVVTLPVF
                     KQCLSQAILLKKQELQAKSLKALDDKTNELLLRNAQNVSTQSAQIARMAGTSSVQIET
                     LEKMYNTIKSGIDETMRIEENNRALIKDNTKRLEELNTTIIYNK"
     gene            complement(12695..14257)
                     /locus_tag="PC466_001787"
     CDS             complement(12695..14257)
                     /locus_tag="PC466_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceG family protein"
                     /protein_id="HDF2769174.1"
                     /translation="MGDSKVFEKIFSSQSDRGNYTPSKGYLSYFISYIGLEDEVLYNL
                     EIFKTKQNIDSKKDIALFTDVIANPSDFDIINYFKSGLQKYRTSMEDVDINILGFEEI
                     DYKIKQAMDRVLKEEEKEFTNDRVKQNFIVKIMAWIKIYIGALDINKNEAPKVIFYGD
                     IKKHEVYLLLILYLAGFDVLYLNPNSKSNIDILKSERYNIEFEEANIIEEKISFEERV
                     ILGEKIDKSSVKKAFTVGAEASKRISEELLNDAGFIKPWQLQDRKIKNLLLSSTVDEI
                     SIYWNQPLKLRPGFKFNDAIVEAPNFLSKINGIYNDKNEYIKFLDLLRDSESSTFIEF
                     NGDVDRFSKAFTREAFSLSFLLDSKGVIDKNSVLNNKDYSISTLALNQQIMILEKVEE
                     LLEGSMFLNGLSGEDKIKGLFTVLHMDKKFVHMMNNFDYSLINPKLIIYMYKSIVFDK
                     EIVFLMLLLSKIGFDIIILCPGGENNIENVINNQLIDIHRLDKMVYDLKLNSLENDIP
                     LLKKIFGKRRRF"
     gene            complement(14344..17103)
                     /locus_tag="PC466_001788"
     CDS             complement(14344..17103)
                     /locus_tag="PC466_001788"
                     /EC_number="7.2.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-translocating P-type ATPase, PMCA-type"
                     /protein_id="HDF2769175.1"
                     /translation="MEFNNDIKYYNVDKEEVTKDLSVNPEKGLSESEVKTRREKYGLN
                     EFTPKEEGSFWDDLKESLSEPMIVILIIAAVVSAVIGETHDAIGIVGAIAIGIAIGMI
                     TEGRSKKAAEALSKLTENIEVKVLRDGEVHQISKSELVPGDIVYIETGDMVPADGRLI
                     ESINLKIREDMLTGESDDVSKKCDVVVSMEEIESKGAVVVQEPIPAKQINMVFGGTLV
                     AYGRGALVVTSIGDNSEMGKIAQNLSETDEQTPLQIKLGNLGGLIAKVSSAVAGLLFI
                     FMVFQMISKNVLNVDMSGILPFLESIDPVKTAFTVCVALIVAAVPEGLPTMINMTLAI
                     TMQKMAKINALVTKKEACETIGSVSVICSDKTGTLTENRMTVEVAYVDGRYIESSEEE
                     INSYFEENCMINSTADVEHNDGDIKYLGSATECALLLYYKNVDYRQVRKNSNIVAQNP
                     FTSDSKRMTSVIGQDNHHVLLSKGAPEVLLELCSHIQRGKDIVPLTENIKHEILEEIK
                     KLQIKSMRTLGFAYKEISQAEEEAAVTAESDAMNVSAMENNLVFSGFVGIRDPLRKDV
                     IESVNTANKAGVSVKMLTGDNINTARAIGEELGLLKNNMRVVEASYIDTLDDEELKQE
                     IQSISIVARSKPDSKMRIVSALQKSGDVVAVTGDGINDAPALSKADVGIAMGISGTEV
                     SKNAADIILTDDSFSTIVKGIKWGRGIYDNFQRFVQFQLTVNVIAFLVAIISQVMGQE
                     MPFTTIQLLWVNIIMDGPPALALGLEPVRDHVLNRKPVDRKANIISKSMVYTIVLNAF
                     YITAILMLQSTFNFLGVDEAHKGTVMFALFAFSALFNAFNCREFNADSIFPNFTHNKL
                     ALQIIVLTGIAQVIFTQLFQDFFNSVAMDFMTWVKVLCVAASVIVVNEVVKCIIRLVK
                     PKKTA"
     gene            complement(17093..17722)
                     /locus_tag="PC466_001789"
     CDS             complement(17093..17722)
                     /locus_tag="PC466_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HDF2769176.1"
                     /translation="MSINLSKGDKIDLKKSNPGLSNILVGLGWDPVQQSGGGFFKSLF
                     GGGQADIDCDASVFMLNQEGKLSGIKDLIYFGNLKSACKSVLHTGDNLTGEGTGDDEQ
                     ILVNLDKVPSNIHKLLFVVNIYNCVDRKQHFGMIENAYIRVEDQGNKKEIAKYNLSDN
                     YSEKTTLIVGAIYRKDGSWQFKAIGEGTKDAGLKEVMQNLDRIECAYGI"
     gene            complement(17808..18386)
                     /locus_tag="PC466_001790"
     CDS             complement(17808..18386)
                     /locus_tag="PC466_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_126936537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HDF2769177.1"
                     /translation="MAIVLKKGQKIDLTKGNPGLKNIKLGLGWDTNSFDSGYDYDLDV
                     SVFMVGESQRVEKDEDFIFYNNLRHPSGAVEHLGDNRTGEGDGDDEEILVNLETMPKH
                     IQKIAVTVTIYEAAERRQNFGQVSNSYIRVLNSENDEEILRYDLGEEFSIETAITVCE
                     IYKYNGEWKFSAVGAGFEGGLEALCRNYGLNV"
     gene            complement(18425..19003)
                     /locus_tag="PC466_001791"
     CDS             complement(18425..19003)
                     /locus_tag="PC466_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_126936537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HDF2769178.1"
                     /translation="MGITLSKGQKVDLTKGNPGLKNILVGLGWDTNKYDGGFDFDLDT
                     AAFLTGASGSVTNDGDFVFYNNLKHTSGAVEHLGDNRTGEGDGDDEQIVVDLSKIPGE
                     ISKISFTVTIHDATERRQNFGQVSNSYIRIVDKDTNEELIKYELGEDFSIETAIVVAE
                     IYKHNGEWKFNALGSGFEGGLAALCGNFGINL"
     gene            19332..20768
                     /locus_tag="PC466_001792"
     CDS             19332..20768
                     /locus_tag="PC466_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HDF2769179.1"
                     /translation="MICTIKPLKISIKKSTEPLIEFISDTTYKNKSSSYIKEVHFTRY
                     IGVDDSIDKYIEKVKNIDTYFFNNPTIPYIRLNNLKINFDKEQTDKMLKIFNIYDSSK
                     FNSWDLYNIDFPCKIENDTLNWTKKIAFKNTLDLFSTSMPNCTSSIIKNFAVKLLCWM
                     DYFLPKLFYNKVKTTISPKIVYFGNIKRQELFFLYFLSQLGCDILYINPNKDILDLYP
                     ECSKFSTLFELSRKTPNILEIPFERHITNINYSENTNKTSPTTNKPNSKNTLNNTNLT
                     SKKIAQDEEVELSYEDLAKLSASVVMIVVCNNENKPFKSGSGVVINNEGYILTNLHVV
                     NDGYSFLVRFENDDKVYTSYQIIKYHSDYDLAVIKVDRKCKPIPVKVSKKPVRGQKIV
                     AIGSPLGLFNTVSDGIISAFRDFETVQMIQFTAPISSGSSGGALLDMFGNLLGLISAG
                     YDDGQNLNLAVESNLVKIFANNFIEIVN"
     gene            complement(20860..22734)
                     /gene="asnB"
                     /locus_tag="PC466_001793"
     CDS             complement(20860..22734)
                     /gene="asnB"
                     /locus_tag="PC466_001793"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HDF2769180.1"
                     /translation="MDGNISIYYKGDISKKEDIKFKIKESVNNTRLSSRIEYKDEEKT
                     FDFERFNVIDAIYGNKPFEKDGKVIVFNGNIYNYHEIKEELIKKGHNFTTNDDIEVLL
                     ASYIEFGKNCVHKIKGMFNFIIYDRENESIFGARDLFGIKPLYYINKENAIIFSSEYK
                     FLLEYMKNLNINERSLQSYFSFQYVLPEDTMIQGIRLIPAGHYFRVENGILSLKRYNK
                     LEFRSSTKFFYTKNHLGNRDVNEDDIRNIVVDSIVTHMEEEKEIGTFLSGGIDSSIIT
                     TVASQINPNIKSFSAGFSVKGYSELEVAKKTADKLGIENIQINITQDEYIKSLPNVIY
                     SLDDPIADPSEVGLYFLIKEAGKHVKVALSGEGADELFGGYNIYKEYSTMKSVVNSPT
                     YIKSILGRVSELMPNIKGRNYLYRATTPLEKRYIGNAKVFENSEVKRFFFKYKEKNIY
                     EYLLSNLYRDAQKNNYDYISKMQHIDVNTWLQGDILQKISKLSTAEQVELRVPFLYKD
                     VFDVAKNLRMEQKINKNNTKVLLREAFREIVPEYVVQRKKLGFPTPIRVWLKDSLGDI
                     VKETIYNSNVDEFIDKKYAIKLLDTHLKGHRDNSRKIWTIFTFCLWHQLFIEHKNVEY
                     "
     gene            22937..23611
                     /locus_tag="PC466_001794"
     CDS             22937..23611
                     /locus_tag="PC466_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HDF2769181.1"
                     /translation="MSLFIISQCITSFAFTPENNKFKVKPLPYAYDALEPYIDKETMK
                     LHHDKHYQAYVDKLNAALEKYPELYNYSLCELLQNLDSLPKDIATTVRNNAGGAYNHK
                     FFFDIMTPEKTIPSESLKEAIDRDFGSFEKFKQEFQKSALDVFGSGWAWLVATKDGKL
                     SIMTTPNQDSPVSKNLTPIIGLDVWEHAYYLKYQNRRNEYIDNWFNVVNWNGALENYK
                     NLKSQD"
     gene            23724..24260
                     /locus_tag="PC466_001795"
     CDS             23724..24260
                     /locus_tag="PC466_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HDF2769182.1"
                     /translation="MIKETHERGGYIFALLILPFINNLYLVKYDIAYKIVLIIIYIYF
                     AYLGSLFPDIDMRGSYISKKFMLIYKLFGSRFRHRGFTHSLIALLLIYSFFKSLTIFT
                     NNNIVFSCLSSGFIIGYLSHLCLDLITKEGIELFYPITINISLLPIKTNSKTEKFISK
                     LLNFIVIFLIGYQFYILL"
     gene            complement(24426..25046)
                     /locus_tag="PC466_001796"
     CDS             complement(24426..25046)
                     /locus_tag="PC466_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HDF2769183.1"
                     /translation="MQYIQELLDLTQNYWVLATIIGLLSAFIESFIPALPLVAIVTAN
                     AAIQGLFIGCLLSWIGSGLGTTSLFLLISRFNDSKLFNKLRNSKTEKAISWMDKQGFK
                     LLFIAYACPFMPGCLVTIASAFGKKDLKDFVPAMLAGKFVMFIVISYVASDIEGFITS
                     PLKIASFILLVFLSWKIGNRVNKNLENHNYDFHHKKHHNDKDDKMI"
     gene            complement(25360..27498)
                     /gene="vanT"
                     /locus_tag="PC466_001797"
     CDS             complement(25360..27498)
                     /gene="vanT"
                     /locus_tag="PC466_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine racemase VanT catalytic subunit"
                     /protein_id="HDF2769184.1"
                     /translation="MIRNKSYAGLDYFRIIAALLIIAIHTSPLLSYSKMADFVLTSII
                     ARIAVPFFFMLSGFFLISTYNYNCNKLKSFLKNVLFIYGIAIVIYIPLNIYTGYFSMN
                     NLVPNIIKDIVFDGTLYHLWYLPASIIGASIAYFLVKKLGLKYSLVITIVIYVIGMFG
                     DSYYGFLEKIPLLKNLYGYIFEVSDYTRNGIFFAPVFFILGGIISNKSNYMSTKNSLI
                     GFLISFLLMLCEGMFLHKLGVQRHDSMYIMLLPCMYFLFTALTFLKGSRARLLRTSSL
                     IIYIIHPMMIVVIRMFSKIFGIQTVLVDNSLIHYIVVSIASFIASIIIILILKPLKKD
                     LKGEHKVNTNRAWIEIDLNNLEHNVKMIQKAMPEDCELMAVVKANAYGHSAFEVATCA
                     NQIGVKAFAVATIDEGIDLRRYGILGEILILGYTNPIRAKELHKYNLTQSVIDLNHAI
                     SLNKQKYNIKSHIKIDTGMHRLGFDVNDVRSILKAFKLKYLDICGIFTHLCVSDSLKD
                     EDVDFTNKQIECFYKLIDFLLKKGIKIPKVHIQSSYGFFNYPNLKCNYVRIGIALYGI
                     LSSPNDTTKLQLDLRPVLSLKSQVILIRKIQKDDSFGYGRVFIASRDSVIAILSIGYA
                     DGIPRNLSCGKSYVIINGCRAAIVGRICMDQLAVDITDIPNVEVGNTAIIIGRDNLSE
                     LSASEVANNSCSISNELLSRVGRRLNVIKK"
     gene            complement(27516..28322)
                     /locus_tag="PC466_001798"
     CDS             complement(27516..28322)
                     /locus_tag="PC466_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HDF2769185.1"
                     /translation="MMNNILLDKNKEDKMTNTILLTKDKVYDGNLILVNAFLPVKTSE
                     DIDLIPVDTRFPSILMKREATNILQNILKSICGINEIVPVSGYRTAEEQQDIYSSSLR
                     DNGKDFTKKFVALPNHSEHQTGLAIDLGLKKEVIDFICPEFPYNGICNEFRKAALHYG
                     FIERYQCKKEEITGISQEPWHFRYVGYPHSEIINKMNLALEEYIEYIKRFSYTNCLKI
                     EDKEKIIEIFYVPIHTKEEVRISIPEQCVYQISGNNKDGFIVTFWRNRKD"
     gene            complement(28319..29419)
                     /gene="vanG"
                     /locus_tag="PC466_001799"
     CDS             complement(28319..29419)
                     /gene="vanG"
                     /locus_tag="PC466_001799"
                     /EC_number="6.3.2.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-serine ligase VanG"
                     /protein_id="HDF2769186.1"
                     /translation="MNNKKIAVIFGGNSTEYDVSLQSAFAVLENLNTEKYDIIPIGIT
                     REGNWYHYIGDYNNIQNNTWFERDTDIIPVIVSQNRVKNGIIEFLIPDAVSQNHIPNS
                     AIESCENDIKYTKLDFVFPVLHGKNGEDGTVQGLFELAGIQVIGCGTLSSALCMDKDK
                     SHKLVHSEGIKVPKSILLKYSDKFNVAELSKDLTYPLFIKPVRAGSSFGISKIYKKEE
                     LQVAVDLAFEHDNEVIIEENIDGFEVGCAVLGNDDLLVGRVDEIELSKGFFDYTEKYT
                     LKSSKIHMPARIDLDCEKRIQETAKIIYRTLGCSGFARVDMFLTPSGEIIFNEVNTIP
                     GFTSHSRYPNMMKGIGLSFEEILDKIIEVYIK"
     gene            complement(29676..30758)
                     /locus_tag="PC466_001800"
     CDS             complement(29676..30758)
                     /locus_tag="PC466_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDF2769187.1"
                     /translation="MRTALMAFIAIIFIWILYSFILYGKFSIWIVSFFENAFRMEYKA
                     ALNLYQQIFRNSMELFMILAMVIVFFIIFRVYLNWFTKYFSEINQGIDSLIKEDVGEV
                     ALSPELLAIEKKINSIKHILEQRKFETQMAEQRKNELIVYLAHDLKTPLTSVIGYLTL
                     LRDESQISEELRKKYLSISLDKAERLEDLINEFFEITRFNLSNISLEYSTVSLTRMLE
                     QLTYEFKPTLMSKNLKYTLNVTPNMMIRCDVNKMQRVFDNLLRNAVYYSFEDTTIEIT
                     AVQEDDYIKLKFINHSNTIPEEKLERIFEQFYRLDTSRNSNSGRAGLGLAIAKEIVEL
                     HNGTITAHSENNIITFKVIIPIVGNL"
     gene            complement(30808..31509)
                     /gene="vanR"
                     /locus_tag="PC466_001801"
     CDS             complement(30808..31509)
                     /gene="vanR"
                     /locus_tag="PC466_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanR-ABDEGLN family response regulator
                     transcription factor"
                     /protein_id="HDF2769188.1"
                     /translation="MNENILIVDDKKEIADLIEVYLKNEGFTVYKFYTGKEALECIES
                     KDLDMAILDIMLPDIDGFHICQKIREKYYYPIIMLTAKIEDIDKIMGLTIGADDYITK
                     PFNPLEVVARVKTQLRRYMRYNNSYEQQSIIVNEYDIKGLIINKETHKCSLFGKEVAL
                     TPIEFSILWYLCEHQGKVVPSEELFEAVWGEKYLDNNNTVMAHIGRLREKIHEPSKNP
                     KFIKTVWGVGYTIEK"
     gene            complement(31943..34474)
                     /locus_tag="PC466_001802"
     CDS             complement(31943..34474)
                     /locus_tag="PC466_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HDF2769189.1"
                     /translation="MSLKSLKIKENLYWVGSLDPDLRVFDIIMYTPYGTTYNSYVLKG
                     TEKTVLFETVKDKHFDNYIERLNDLNIDFEKIDYIVVSHTEPDHAGSVEKLLDLAKNA
                     KVVASETAIKYLKEIVNKDFEYVAVTDGDTLSIGDKTLEFFSVPMLHWPDTIYTYIKE
                     DKTLVTCDSFGSHYSNDKIVNTLDENEEKDYLDALRYYYDCIMGPFKPSMVTAIEKIK
                     DLDIDTVCPGHGPVLTENPRKIIDLYYNWSVKEQIKLEKEVTICYVSAHGYTKIMAEA
                     IKAYIEKNSNYKVNLFDVIEHKQEDILAKIAVSQGVLFGTPTILGDALKPIWDILISL
                     NPVLHGGKVASVFGSYGWSGEGIENAMERISQLRMTAVKPFAVNFKPSNEEIDKLHSY
                     TGKFLDKLNSTFGSKKKTKKFKCVICNEVFEGDSAPSVCPVCGAKEDQFIEVEEDEVT
                     FRKDTDEYFVIVGNGAAGFYAADAIRKRNKTCKITMISNEDELTYYRPALSDGINEEL
                     GSDFYMEDKDWYDKNNIVVILGTNVDKLDEVNKTIIVNDGAIKFDKLVIATGSRNFIP
                     PIKGHDLENVFTLRNIKDLYSVKEALEKSKKVVVIGGGLLGLEAAWEFRLKGLEVVVV
                     EAMDSILSKQLDKEGSKILEQCVRDTGIDVRLGVAVDGIEGDGKAQKVVFKDGDSVDC
                     DMVVFSIGVRANTQMVQDTSVKIDRGIVVDKTLQTNVKDIYACGDVAQVGNISLAIWP
                     SSVEMGKIAGANASGDNLTFESEVYPVSLDAMNVKVFSIGNIQNFDKEISSKDEGQRI
                     YKKLFMKDGSLVGAILINDLSCTVKLIRLISEKGDFEDIMKADIL"
     gene            complement(34582..35199)
                     /locus_tag="PC466_001803"
     CDS             complement(34582..35199)
                     /locus_tag="PC466_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HDF2769190.1"
                     /translation="MCKKTYLLVVSILIAGLLTACSGSPTKDSGQAQDNTKKEANASN
                     NALKDEKNNENLMEQDFKVPYTDAINIFKDKYKDADIVDLSLERDLNKFVYTVEGVDD
                     NNEYKMKIDANTKDVLEDKTEKLDSEDLNGVARKEKLDLNDIITPQQAMEIALKEQNG
                     MVKEWSLDKDLDVTFYKIRIDKDKNEYDIKVDSKKGTVLKVEKED"
     gene            complement(35561..36445)
                     /locus_tag="PC466_001804"
     CDS             complement(35561..36445)
                     /locus_tag="PC466_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HDF2769191.1"
                     /translation="MDTTKIDDISKLDLNNLDINKMDMGGIMESLLEWATTSGVKLII
                     GILILSIGFKIIKKFVNHVMLVLSKRDIDLTLRRFLKSLLLSVLKVAVIIIVLEYWGM
                     SLSSFAAVIASAGVAIGLALQGSLSNFAGGFIILLIRPFKVGDYVEAAGHGGTVEQIG
                     LFYTQLVTPDNKQILIPNGSVSNDSLINYSAKNTRRVDLTFSVGYEDDILHVRRVLKD
                     IVNNHKLIINEPEPFIGVVEHGDNAVKFATRVWCKTEDYWTIYLDLLEEVKVRFDEEG
                     ITIPYPKMDLTVKELNKI"
     gene            complement(36636..37886)
                     /locus_tag="PC466_001805"
     CDS             complement(36636..37886)
                     /locus_tag="PC466_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2769192.1"
                     /translation="MKSYTKAKWSVWGIITFSFVLVLFLRMSTAVVSDNLANELGFNS
                     IQISNIASFCLYAYAFMQIPAGILIDKYGARKISSLGIIMASLGSILFGLIQSIELAY
                     ISRVIVGAGTSVILLCILKIQGRWFNKSEFASATAKFSFVGNLGGVLATFPLVFLSEL
                     VGWRNSFLLIGIIGVVIGCFIYIIVRDTPKEYGFNVDTEPYEKSEKVNIVDGIKSVIK
                     NKSTWYNSMIMFSFVGLTSAFISLWGVRYIMDVYGVSKSFSAFIVSFFTYGFIFGSII
                     MDFVFAKIRSSKFNIIKFGAMIDLFIWIVIVVVYQVKPPIIVLPISFFIMGCIVMSHL
                     QVFNDAKYKNKEIYSGLATSVINTFEFIGSGIINLIIAISLQVNSYNIVDGYKKGFVV
                     FIVLSIITIVSSHIGVKNDDCKAI"
     gene            complement(38108..38872)
                     /locus_tag="PC466_001806"
     CDS             complement(38108..38872)
                     /locus_tag="PC466_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2769193.1"
                     /translation="MLGKLLKYELKASGRIFIPLYIAILIVAVFNGIFMNTNILQVQG
                     IGILVLTSLFMALGVLTIVVTIQRFRKNLLGDEGYLMFTLPVSTSSLILSKCITALIY
                     AVLSFIVAVFTFGVLMLFGTSGILLPEILDLFNTSFKWISENFLDILLLVVVMFISYS
                     SFILLLYTSISMGQLPKFNKHRNIVAFASFIAINIVISIVGDAVGSILPNEDTNMVYH
                     LYQSPSFMLAILGSLVVAIALFFATKFILDKKLNLE"
     gene            complement(38866..39591)
                     /locus_tag="PC466_001807"
     CDS             complement(38866..39591)
                     /locus_tag="PC466_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2769194.1"
                     /translation="MDKNISNVSQDGIVEFKGVNKSYGTKNVLKNIDLNIPKGKIVGL
                     LGPNGSGKSTMIKLMNGLLQPDNGEIMINGMKPSIDTKKIVSYLPERTYLNDWMKVSD
                     LLKFFYDFYSDFDVRRANEMIKSLDIDVNEKLKTMSKGTKEKVQLILVMSRNASIYIL
                     DEPIGGVDPAARSYILKTILKNYSEDSTLLIATHLISEIENICDEIIFISKGEIVLQG
                     DVEAIREEKGKSIDALFREEFKC"
     gene            complement(39593..39961)
                     /locus_tag="PC466_001808"
     CDS             complement(39593..39961)
                     /locus_tag="PC466_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2769195.1"
                     /translation="MEWELDNNKPIYIQLVEHLKLKIISGEIKIGSKLETVRALAEDA
                     EVNPNTMQKALTELERQGLVYSQRTKGRFVTDDKEKIKAMKEEIANVEINTLKVTLEK
                     LGYDRDEMLKLITENLKGEL"
     gene            complement(40137..41681)
                     /locus_tag="PC466_001809"
     CDS             complement(40137..41681)
                     /locus_tag="PC466_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HDF2769196.1"
                     /translation="MRNLQKKLMFFLFICIILQITYTTPVYSLCKLYKNNSINNFESI
                     VSNNQFISKYAIQIILIMAIICMMLIFYIIYDKLNFKIKLQKIAYTDNLTGANTIDKF
                     VIDANKILCKNTQVKYALLYIDIDKFKYINDLFGYEVGNEILRNLTKIIKSNIFEEEM
                     FARISADNFIIIMKYIEEEDITKRLKTIFEELDLFNNNQEEKYKLVLSCGIYFILPED
                     RDINSIIDRANIPHKMAKGGHKSSYAFYDNKIHDQEIKEKEMENTMFSSLENKEFIIY
                     LQPKIDLNTGEIQGSEALVRWKRPDKGLIPPNEFIPFFERNGFVINLDLYVLEEVCIY
                     LRKWIDAGINPVTVSVNVSRIHLYCNNFIETYKNIIDKYNIPAKYIELELTESIIFDN
                     FDILIDIMNNLKKIGFLISMDDFGSGYSSLNMLKEIPMDILKLDQKFIMETYNSKRSK
                     IIVTKVIEMAKELGMKVISEGVETEEQFKLLKEVKCDMAQGYLFGKPMPIEEFEHLIV
                     SNLVRG"
BASE COUNT        14095 a         7246 c         4314 g        16327 t
ORIGIN      
        1 attctttttg tctagtataa cttcatattt tattagattt tgaatagatt tatcttatta
       61 taaataatat tattgtttaa actatatctt tattatgcaa aaaataaact aggagttctt
      121 aaaaactcct agtttatttg ataatcattt tacaaaaaat acattttgat tatatcggat
      181 tattaattta ccgcttttga agcatcatct atcattttat ttaaagatgt tagaccacca
      241 tcatttacat accatgttgg tgaatctaaa tatattatat tatcattctt atatgcatcc
      301 atagatttta ttatatcatt gttcaaaaca gattttgcag ttgagctttc ttttacatca
      361 ctaccagtag ctattcctct atctataacg aacataactt ctggattttg tttagctata
      421 tattcaaaag taatattttg tccatgactt gattctttta tatttttatc tttattttca
      481 aatccaaaac tattgtataa tatactaaat cttgattctt caccaaatac acttaaatta
      541 ccttcattta ccattatagt taaagcattt aaatttttat ctgttacttt tttattcaaa
      601 gtttctattt tcttttcaat tttactaaat tcttgatttg ctttttcttc tactccaaat
      661 atttttgcta ttttgtctat attattttta acagattcta agtacttctt atcatcttta
      721 cttgtactta ttgttggtgc tatttttgac aattgttcat aaaaatcttc ttgtcttcca
      781 tttattataa ttaaatctgg atttgccgac tttatacctt ctaaatctgg ttcttttaaa
      841 cctcctaaat ctgcatactt cttatcctta tatttttcta aagatgctgg taaactcgtt
      901 tttggaagtc ctactaaatt ctcagctaca cctaatgcat ccattgtatc taaagccgaa
      961 taatcaaata ctactacttt tttaggattt aattttacat ctgtttctcc caagttatga
     1021 gttatcttta tggtattatt tgaattttct gatgtttttg attcattctt tttacttcca
     1081 cctaatgcaa acactgtcac taatcctata atagctactg ctgctactat tgctgctttt
     1141 ttattcatat caatattttc ctctctccta ttaatcttta ttttaattta aaaactttat
     1201 aaaaaatcat atagcaagct tattttcata tacaatattt taaaaataaa tacagattcg
     1261 atttccattt atattcttaa tgttaaaatt catctcataa atatcttcta aaactttttc
     1321 atttactatc tcatctgtac gacctacttt ttcaactttt ccatttttta atgcaactat
     1381 attatctgaa taacatgatg caaaatttat atcatgcatt actaatacta tagtcttatc
     1441 taactcatca caaagacttc taagtacctt catcatctgt acggaatggt tcatatccaa
     1501 attgttcagt ggttcatcaa gtaatatgta ctctgtatct tgagctatta ccattgctat
     1561 ataagctctt tgtctttgac ctccactcaa ttcatctaaa tacttatgtt gtatatcagt
     1621 caacttcata tattctattg cttcatcaat ataattttca tcctctttag ttagattacc
     1681 ttcactatat ggaaatcttc caaatccaac taattctctt attgtaagct ttaaagttat
     1741 attgttagat tgtttaagaa tagctatttt ttttgctaat tctttattgc tataattagt
     1801 caagcttttt ccttctatta ttacttctcc gccatcacct cctataagcc ttgtaactat
     1861 tgatagtact gtactttttc cagctccatt tggtcctata aaagatgtta tctttccctt
     1921 ttctatacta aaagagacat catctacaac atttttattc ttatatcttt taaatatatt
     1981 ttttatctct atcatctatt tgcccccttt aatagtaatt gaataaagta aattcctcct
     2041 ataaaattta ttactacact taaagtcgta tcaaacttaa atacatgttg tataaaaaat
     2101 tgacctatta tcaatgtaat catccctatc aacatagaac ccgaaatcaa gtatgtatgc
     2161 ttatatgttt taaaaatttc tcttgttata ttagcaagta aaagtcctaa aaatgtcata
     2221 ggtccaataa gtgctgttga tattgagact aaaattgcta ttaatattat cattttttta
     2281 actgccttat caaaatctac acctaaatta attgcttgtt ctttacctaa cgacaataca
     2341 tctaaatact ttatttcatc atatataaaa ggtattatgg caataattat tataaatgct
     2401 attaacaata cattagtgtt tatattgttt aaacttgcca ttatactagt ttgtaaagct
     2461 aaaaattcat tcgggtctat cattacttga ataaatgttg ttgcactttt aaataaggtt
     2521 ccaaatatca tacctactag gattaaaaag aaaatattat ttttattttt ttcaaataac
     2581 atcttatata ataacaatga agctccaatc atcatagcta cattaataat aaaattataa
     2641 ttttcattta taatcagact actgcttgaa ccaaatatga atactattat agtttgaatc
     2701 attacataca atgaatctaa acctagtaca cttggtgtta atatttgatt gtttgtaatt
     2761 gtttgaaaca ctacagtagt aaatgctata catcctccac ctaataccat agcaaatatt
     2821 tttggtattc tttgtgataa tgcatattct aaatgattca tgtctattcc ataaattata
     2881 aaaagtgcta ttgatatgaa tagtaatata cttacaaagt aaattttttg attgagacta
     2941 agcttcattc acattcctcc ttaatattaa ataaaggaat agtatacttc ctataactcc
     3001 aactgtaagt cctatagata tttcatatgg ataaataata attcttccaa aaatatcaca
     3061 tataagtaca aataccgctc caagtaaacc agtataccat atgcttgctc ttatattatc
     3121 acccatatac aaggatacga tattgggaac tattagacct ataaaaggga tattaccagc
     3181 tgtaacgact acacatactg taacaagtgc tactattatc agacctatat tgacaattct
     3241 tttgtaacta agacctaagt ttgtcgcaaa atccataccc ataccaacaa cagtaaattt
     3301 atttgcataa atatatgcta atattataag gggtattgtg atatataata tctcataatt
     3361 tcctttaagt atcatagaaa agtcaccttg catccaagaa ctaacatttt gactcaaatc
     3421 gtatttatac gcgataaaat ccgtcataga acctattata tttccaaaca ttatacctac
     3481 taatggtaca aagattatat ttttaaattg taacttccct attattttca taaacgtaaa
     3541 agtccctaca agagaaaata caaatgctat tattgtcttt gtaaaaatag aggcagttgg
     3601 tactaaaagc atacatatta ctatcccaaa ttgagctgca tctattgtag cacctgttgt
     3661 aggtgataca aatttattct tacttatctg ttgcattata agacctgcta tgctcattcc
     3721 tacaccagca atcaatatac ttattaatct tggtacccta ctcatgataa atatcataag
     3781 cttatgctga ttttttgcaa atatatgcat tatatttata tcttcagctc ctataaataa
     3841 agaaaaataa gacaaaatta ttattcctat gactaaatac cttttcttca ttctccctcc
     3901 ttaaaaatct tttattaatt aaaatgaaaa ttattatcat tttcactttt atagtttatc
     3961 aataataatt atcattgtca atatatatct atatctattt ttaacataaa aaatgttact
     4021 agaattgaaa cttctagtaa cattaaaatt taatttaata aattatgaac gccaatttaa
     4081 atatgtagat attattgtat aaatatacta ttttataaat ttaagttctt tattatatta
     4141 ttttagtata tctttaaaga gcctataaaa attaccacta gagattaact ctatatcttt
     4201 ctttttataa cctctatttt caagctctac tactatgttc tgtgctgtat gtgtgctttc
     4261 aagaccatct acacttggca cactagcatt tccagtaaaa gaacctatag tctctttccc
     4321 taagtaatca ctaaaatcaa aaccaaaaga tacatgttct atacctataa gatttaccat
     4381 atagtctata tggtcaacca aatgtattaa atcttgcttc ttaggattac tattagtaaa
     4441 tcctctaaaa ctatttattc caactaatcc acctgtattt gaaatttctt ttaattgatt
     4501 atctgtaaga tttcttttag catcacataa actcctagca ttagaatgag aagctataac
     4561 tggcttactt gcaacagaca ttaaatccca aaatgatttt tcatttaaat gtgacacatc
     4621 tactatcatg cccaattttt ccattttatt gactgctttt ttacctattt cagttaaacc
     4681 acgattttca tcccctaaac atcctgtagc aagttcattc tgttcattcc aagttaatga
     4741 tgcatgtctt gcaccaactt ctttataaaa ataatctagt aaatctatat ttcttccaat
     4801 atggcttaat ccttcaagac caattaaaat atttattttg ttttcactta tacctttatc
     4861 tatatctgaa tattttttta ctatgtttac aacatctttc atatcttcaa tttcatcttt
     4921 tatagagctt ataatttgtt taactctttt ttcaggctct ttatcatatg gtgggtctat
     4981 ccatattaca aaaatagctc cttctatatt tgctctttta aaattatcaa gatggattct
     5041 tctaaataca tctttttccc cgttaagcct tcttattgtt acatctgccc aagtatctga
     5101 atgtccatcg aaaatcataa caacctccaa ttaaataaaa atctttctaa aaaacaactt
     5161 cttttcacgt aaaattatat caaaatattt cctactaaaa gaccaaaata attaccaact
     5221 atgtatccaa atgttccaac tataagtatt ggccctacta gcttagacca tccttttgat
     5281 attgccatag ctgctgctgt tgtaggacca ccaatatttg cattagatgc aagaatagct
     5341 tcttctaaac taaacttaaa tatttttgca actataaatg taactagcat gtttattagt
     5401 accattattc cgcagtataa aagtagtaat ggtgattttt gaattattaa tgttattgaa
     5461 gcaggaacac ctactacaac aaagaatata tatattaaaa atgtacccaa ttcctgtgct
     5521 ccttttatat caccaaagaa attaggcata aatgtggcaa acaacatagt caaagtagtt
     5581 attattagat attgatttcc aaataaagta tttaacattg ctaaaaaagg atttgataat
     5641 ggtattatag ctttaaacca agttgatagt tctacagata ctgcgacaat tataaaggcg
     5701 ctaccaatgg ctattgctat atcttttaaa gatatttctt ttcttcccca ataatttgct
     5761 gctactgttt ctccttcagt tatacctata ctttccattt catctacatg tggatgttta
     5821 aaatgttttc taaaaaatcc aattgatggt atagctatta agacaaagaa atataatgcc
     5881 attaaaagat tatctgctac aactgttgct gatactaatt ctcctggcgc atcaaacgcc
     5941 cctgacatag cagcaaagtt tacatttcca cctatataag aacctgtcat catagctgca
     6001 acaatattta aatctggtac tacatttttt aatgctaaaa atccaatcat agctccaagt
     6061 acagttccta cagaacctac aagaaatata atgagcaatc ttccactttc tttccatatc
     6121 tttttaatat tacattgata taacaataaa gctatggcta aaggaacaac atatccccat
     6181 acttggtcat atacaacaga ctctactggt ataatattta gatttgataa taacattgct
     6241 cctacaagag ctattattgc tcccgacact tttgatgccc aattgtactt ttgttccaag
     6301 taaatactaa atgctgccca tccagttaca actgcccata atacccaaat attatcagga
     6361 cttacaaaac tcttcatctt aattacctcc atttcattaa attaaaatat cattatcaat
     6421 attcaatata ttgaatatta atactattat aatgcatctt ttcagaaaat tcaatataac
     6481 ataaaaaata catgcattat aaaacttttt tttattttat taatctttat aaattatatg
     6541 ttataatcat gtctgagggg gtttgtatct aatgaatata gatgtcggaa gcaaaattag
     6601 atctcttaga aaatctaaaa atataagtat ctctacttta gcaaaaaatt cagatttaag
     6661 tacaggctta ataagtcaaa ttgagcgtaa tatggttgtt ccatctattg tagcaatgtg
     6721 gaaaatatca aaagctcttg atataaatat aggttatttt tttgaagaga ttggaagaga
     6781 ggactctgat atagtagtaa agaaaaataa tcgaaaaaaa atagtaacta atgattctac
     6841 aaaattttat gaacttcttg ttcctaattt atctgggaaa aaaatagaat ttatacttgt
     6901 tacgctagat ggtcatacac aaaaaaacag tgaatttgtg acacacgaag gagaagaatg
     6961 tggctatata ataaaaggta aaatgaagat aacacttgga aataaggaat atctattgga
     7021 ggaaggagat agtttttatt ttaacagtac tataccacat gtgtatgaaa attatgatga
     7081 tgaggtatgt atctcagtct gggcaatgac tccaccttca ttttaacata ttgagttctt
     7141 acttaaatat aaattgataa aaatctgaaa taaattagta tgataaactt tactataatt
     7201 tatttcagat ttttctagtt tattatttat atatcagtca ttatatatta agtaggcagt
     7261 tctcgtctaa aatgttagat aatatctctt cagttccact cattcctttg aaagaacttg
     7321 atataaatga attttctatt tcatttttat ttatatcacc atgcttcaat acataggatt
     7381 tatttgagat attaagcata ccatagtcca taatagaatc tccaactgca taaaaatatt
     7441 ctattcctaa ttctttagtc aagtatttta tagcattttc ttttgaaatt tcttttggta
     7501 taaaatatat ttttctgcca ctcacataaa acttccaatt ttttgattcc aatatatttg
     7561 tatattcttt gattgaatcc aaattaaatc ttgagaaatc aacaactata taaaaaaatg
     7621 tatcttctgc aactttaaaa ttagttattc catctacatt caaatagtct ttaaatttat
     7681 gaatcatact ttcaatgggc tcataatcag gttttagttt atctattttt tcactccatg
     7741 atttcaatat ttcattatct ttaagtataa ctcctccatt tgaagttata ctccaaggaa
     7801 aataaatccc atatttatta aattctatac gcttaaattg ctccactgtt ctagtagttg
     7861 taggtataaa cataccataa tattgtattt gctttattaa atttatagta tctaaagata
     7921 tataagatat ttctttttcc ctataaattt ctatattagc atatttacta tcagcattta
     7981 aaaatttatt ggagtaaatg atactcctgt ctaaatctga aaaaacaatc attcaatatt
     8041 ctcctgtcta atatatttcc taaatatctt tcatattttt tattattcca caacatttat
     8101 aggcttttaa atccatttgt tcaacttcaa catttttctc cttagctaat atgaatatat
     8161 ggtctaaaga tttatcattt aagtctttaa caagaatctt atacggaact cttctaagta
     8221 aaacccttgt cgtttcccct acacctggtt tgataaagtt aatatctgtt atgttatact
     8281 tttcttttat atttaaaaca tcaaagtatc catctcttgt tataatgtca ctttcccagt
     8341 tttcaacttc atcagatata ttcttaaatt gatttttaaa acattcttct atagtttcga
     8401 tatagttcat agattcatct ttatctttta aatgtctata aaacttagct ccatgaaagt
     8461 catttttacc aattaaatcc tctcttagta cagttctact tactaaacca gaaacggttg
     8521 aatttaaaca tgcacttggt attaagaaat cttctctaat tccataaagt cctgaatatc
     8581 cagcagggtc agctaataca gcaagtgttg agtcaaaatg ttttttaaat ttaacattaa
     8641 gttcatcaca tgctttttca agttcttttg atatagttcc cttaccagtc catccatcta
     8701 aaaattgaat ttttgagctc ggatgattct ttactatata ttcaattgca ttcatatcta
     8761 ttcccttatc tcttattata gagattgtat agtgaggtaa acttacatta tacttgcttc
     8821 ttatatatct ttttgccaaa ataccaatag gtgttcctgc tctagcaagt gaaactagta
     8881 ctacatcatt tccatttttt ttaattattt tttcacacat aactcctata gaaaatgcaa
     8941 gcttatcttt attttctctt agtttctcat gatataaatt cagataatct tcactaactt
     9001 catactctat tggtatcatt tctgaataat gtctaccatt ttgtattttt aattctcttt
     9061 ctttatttcc ttcttcttca attaaatttg atatatcttt taataaaaaa ataacatcat
     9121 ctttagaata cgtgctaaaa tctctcatat gactcaactc ctatcttaaa atcgtgatat
     9181 attttatcct gttaaaacac tttagctaca acatactata gttaattctt ttatacttgt
     9241 ttttttaatt atatcaataa attctagata agaattttca cttttattca gctctacaaa
     9301 taaataacac ttagaaaaat tatgtttatc tatattgtaa atataatttt gaatatctat
     9361 attataaaaa ctctttagca taaatttact tttaatagga taatgcttct tatcaatatt
     9421 aataattgga cttcttgttg ttgaatgata gtatatatca tattgatttt ctttttcttt
     9481 tgcaaacagc ataggtatat acataaattc ttcagtacct aaaaatagaa tcttttcttt
     9541 ttcatttttt aaagattctt tactggccat agttattttt ttactttctc tcttaacgat
     9601 ttcttttaat ctaaattgtt ctcttctatt aattccaaat cttcctgtat attttacata
     9661 tttcttattt ccaatataat cttctaaatc aacataaata tgatttacta ctaaatttac
     9721 tttatcactt gaaatagtct ctaatttagt aatactataa ttatcgttgt aatttgaaat
     9781 aatatcttca tctatataaa atttaaagtt tcctttaaat aagtatacaa aatctatctt
     9841 acaatttagc tctctttcta aacgagtaac tttacttaaa ttttcatcac ttacccaatt
     9901 gagtattgag catatagtgt atttcttttt aggataaatg ctttgaattt tcctaattat
     9961 attcatgcat gtattggctg tggtaatctc atcatcaacc aatattatct catctccaaa
    10021 tttaaagttg ttaagcatac caaagtataa attctggtct gttgcatggg aatgttcctc
    10081 taaaaattcc agattttcta actcgtcaaa ctgctctcta gtagtatgaa taaattcata
    10141 atctccacat aagtaatcaa aaaaactatg cccaacagct gtaccagttt cagcaaaagc
    10201 tataacagta ccatttgatt cttccttatt tttttcatta taaattgtag ccattaattt
    10261 tcccaaatta tccatctcac ttggcttaca tgctaaatgt ttaccgagtt tctttgagat
    10321 aaacaaaaaa cgtcttttgc tattatttct tactcctacg tctaaaaaat catttagttc
    10381 taaattcaat ggattatcaa taatgtcaat ctcacaatta aaatttaagc aattcttcat
    10441 agtctactcc tttatttaat acaccatata ttttagatag aatcaatgtt tttttagccc
    10501 ataaaaaatg tggatttgtt tcattcattc tctctcctaa tacacccttg ctcacaccat
    10561 acttactgtc tgtactatcc agtatatcca aagcatcagt aaaatcttca tatgatactg
    10621 tagatagcgc ttgtacaatt tgaatttgca ttggatgaat tacggtcttt ccaattaatc
    10681 catgatattt atccaataat atttcttcta tatacttatt tcttatatcc ttatttgtca
    10741 tatcaaaaaa ttctgatact ccaccactta taggtatatc taactctggt ctttgaagat
    10801 atgtgattat atctaatata aatgaagaac aaatcaaatt attatatata gagaagtttt
    10861 tatctctcct tataccatac atccctaata tatcagttat gcctactcta atgcttaata
    10921 ttcttgactt atgtcttaaa atagcattgt acaaattagt aaaactaagt tctttttttt
    10981 cattatatat aaattctctt gtctctatta ttggaataac atacatatct tgaagattca
    11041 tagaatataa agcttctata caattttcaa tcaactccga atttgcttta ggaattaata
    11101 ttcctgttat agaatgacta tttttaatta taatctcttt aattctcaac agttgctcca
    11161 catcttttat tcttacaaaa attagtggta ttccatcttt attagttata ctttcattgc
    11221 taatattttt taaaattaat ctaagatttt ctatagcctc taactctcca tttactccaa
    11281 cagcatcttc taaacaaata gctaatggtc taactccctt aacatcccct ataatactct
    11341 tataaatcat attatattga gtagctggaa cgtataaaaa agcgcccagt gcatatttca
    11401 acacatcttt ttcagtctta gcactaaagt cttctggctc cttcaaaaaa attctctcca
    11461 aatcatcttt gcagatataa tcgaaatatt tcaatgtcta gcctcctcat atacatagaa
    11521 agggccaact ttatacaaat tagcccttaa tataatacta cttattataa attatagtcg
    11581 tatttaattc ttccaatctc tttgtattat ccttaattaa agctctattg ttttcttcta
    11641 ttctcatagt ttcatctata ccagacttga tagtattgta cattttttcc aatgtttcta
    11701 tttgaacaga acttgttcca gccattctag ctatttgtgc actttgagta cttacatttt
    11761 gtgcatttct aagcaataat tcattagttt tgtcatcaag tgcttttaga gattttgctt
    11821 gtaattcttg ctttttaagt aatatagctt gagataaaca ttgtttaaat actggtaaag
    11881 ttacgacaaa tgcactattt atttttctaa ttaaaccata attattatgt tgcatacctc
    11941 taagcatagg tattgtttgg atagctatat tttctgctat tcttaaatca tagactcttt
    12001 gatttaacat atcataaact tttaatagtt cttgataatt gacaacatcc atttggtctc
    12061 cactagtctc tgatttttgt ttaaagaaag gtagtatttc attatccatt tcttctattg
    12121 ccatttctcc agcaacaata tatttttgaa gttcattata aaactcaaag ttttcattta
    12181 acatagcacc tatttgctta ttagaaagtg ctatatctct ttcgtattgc tcaagctcaa
    12241 tttgaatttt ctcaacttct cctcccaatg tttcatactt ttgaaacatc atttcaatgg
    12301 cattattagc ttttttgaaa agtttttgaa cgaaatttgg ttccttagtt tcttgaaaat
    12361 cgtctaaatc aaacttatcc attattttag ttaaatgaac cagcatttta gaattttctt
    12421 catttctatt taattttatt gtatttaaaa ggctatcaga aactcttgct actccttcag
    12481 atgctttcct accaaactgt aaaatcgtat ctggattttc tacttctata agggatgtca
    12541 atgcctcaac ttccttagac tttctcagtt catttttttt attatttgta tattccatta
    12601 tatcgaagtt ttcttcttga actgctgtag gcaaattctc agtaacctct acagagttct
    12661 tatcttttga aaaactattt atatttatcc ccatctaaaa tcgtctcctc tttccaaaaa
    12721 tttttttaag taaaggtata tcattttcaa gcgaatttaa tttaaggtca tataccattt
    12781 tatccaatct gtgtatatca atcaattggt tatttataac attctctata ttgttttctc
    12841 ctcctggaca taatatgata atatcaaatc caatcttact aagtaaaagc ataagaaaaa
    12901 ctatttcttt atcaaataca atactcttgt acatgtatat aatcaatttt gggtttataa
    12961 gtgagtaatc gaaattgttc atcatatgaa caaatttctt atccatgtga agtactgtaa
    13021 atagaccttt tatcttgtct tctccactta aaccattcaa aaacatactt ccttctaaca
    13081 actcttccac tttctctaaa atcataattt gttgattaag tgctagtgtt gatatggaat
    13141 aatctttatt atttaaaaca gagtttttat ctattacacc ttttgaatcc aataaaaagg
    13201 ataaactaaa agcttctctc gtaaaagctt ttgaaaatct atctacatct ccattaaatt
    13261 caataaatgt tgaactttcc gaatctctta ataaatctaa aaacttaata tattcattct
    13321 tatcattata tattccatta atcttagaaa gaaaatttgg agcttctaca atagcatcat
    13381 taaacttaaa tcctggtctt aatttaagtg gttgattcca gtatattgat atttcatcaa
    13441 cagttgaact tagaagtaga ttttttattt ttctatcttg gagttgccaa ggttttataa
    13501 atcctgcatc atttaacaat tcctcactta tacgctttga tgcttctgcc ccaacagtaa
    13561 aagctttttt tacagaactt ttatctattt tttcccctaa aataaccctt tcttcaaaag
    13621 aaattttttc ttctattatg ttggcttctt caaactctat attgtatctt tctgatttta
    13681 aaatatctat attactcttt gaatttggat taagatataa aacatcaaaa cctgccaagt
    13741 ataatattaa gagtaaataa acttcatgtt tttttatatc tccataaaat attacttttg
    13801 gagcttcatt tttatttata tctaaagcac cgatataaat ttttatccat gccattattt
    13861 tcactataaa attttgttta actctatcat tagtaaattc tttttcctct tcttttaaca
    13921 ctctatccat tgcttgcttt attttataat caatctcttc aaatcccaaa atatttatat
    13981 ctacatcttc catgctagtt ctatattttt gaagtccact tttaaaataa tttataatat
    14041 caaaatcact aggatttgct ataacatcag taaataaagc aatatctttt ttgctatcaa
    14101 tattttgttt tgtcttaaat atctcgagat tgtacaaaac ttcatcttct aaaccaatat
    14161 acgaaataaa ataacttaga tatccctttg aaggagtgta atttcctcta tctgattggc
    14221 tggagaatat tttttcaaat acctttgagt cacccataac tatcctccca atttaaatgt
    14281 ttattcagaa ctgacccaaa attcatattt tgagtcagtc tgttttcttc taaaaaattt
    14341 gttttaagca gtcttttttg gttttaccag tcttattata cattttacaa cttcattaac
    14401 cacaattaca cttgctgcta cacataaaac ttttacccat gtcataaaat ccattgctac
    14461 agagttaaag aaatcttgga atagctgagt aaatattact tgtgcaattc ctgtcaacac
    14521 tattatttgt agtgctaatt tgttatgtgt aaaattaggg aagatactat ctgcattaaa
    14581 ctctctacag ttaaatgcat taaacagtgc gctaaaagca aataacgcaa acattactgt
    14641 tcccttatga gcttcatcaa ctcctaagaa attaaatgta gattgtaaca ttagtattgc
    14701 tgttatataa aatgcattta atactattgt atacaccatt gacttagaaa ttatattggc
    14761 ttttctatca acaggttttc tatttaacac atggtctcta actggctcta aacctaatgc
    14821 tagtgctggt ggtccatcca taattatgtt tacccataat aattgtattg tagtaaatgg
    14881 catctcttgt cccataactt gagatattat agccactaaa aatgcaatta catttacagt
    14941 taattggaat tgaacgaatc tttggaagtt atcataaatt cctctacccc atttaatacc
    15001 ttttacaatg gtactaaaac tatcatcagt taaaattatg tctgctgcgt ttttagatac
    15061 ctctgtacca gatataccca ttgctatacc aacatctgct tttgaaagtg ctggagcatc
    15121 atttatacca tcacctgtta ctgcaacaac atccccgctc ttttgcagag ctgaaactat
    15181 tctcatttta ctatctggtt tacttcttgc cacgattgaa atactttgta tctcttgttt
    15241 taattcttca tcatctaaag tatctatata tgaagcttca accactctca tattattttt
    15301 taataggcct aactcttcac ctatagctct tgccgtattt atattatctc ctgtaagcat
    15361 ttttacagaa acaccagctt tatttgctgt atttacagac tctataacat cttttctaag
    15421 tgggtctctt ataccaacaa aaccactaaa tactaaatta ttttccattg cacttacatt
    15481 catagcatca ctttcagcag ttactgctgc ttcttcttca gcttgtgaga tttctttata
    15541 tgcaaaccct aaagttctca ttgattttat ttgcaatttc tttatttctt ctaaaatctc
    15601 atgttttata ttttcagtta atggaactat gtcttttcct ctttgaatat gtgaacataa
    15661 ttcaagtaag acttctggtg ctccttttga taatagtaca tgatgattat cttgacctat
    15721 aacagaagtc attctctttg aatctgaagt aaaaggattt tgagctacta tattagaatt
    15781 ttttctaact tgtctataat ctacgttttt gtaatataaa agcaatgcac attcagtagc
    15841 acttcctaaa tacttaatat caccatcatt gtgctctaca tcagctgtag agtttatcat
    15901 acagttttct tcaaaataac tatttatttc ctcttctgaa ctttcaatat atctgccatc
    15961 aacatatgca acttctacag tcattctatt ttcagttaat gtaccagttt tatctgaaca
    16021 tattacagaa acagaaccta tcgtttcaca agcttctttt ttggtaacca atgcatttat
    16081 tttagccatt ttttgcattg ttattgcaag tgtcatattt atcatagttg gaagaccttc
    16141 tggcactgct gcaactatca acgcaacaca tactgtaaat gctgttttaa ctgggtctat
    16201 tgattctaaa aacggtaata ttccagacat atctacattt aatacattct tacttatcat
    16261 ttggaaaacc ataaatataa atagtaatcc tgctactgca ctagaaactt tggctatcaa
    16321 accacctaaa tttccaagtt ttatctgaag tggagtttgc tcatctgttt ctgataagtt
    16381 ttgagcaatt ttacccattt cactattatc tccaattgaa gttacaacta gagctcctct
    16441 accataagct acaagtgtac caccaaacac catatttatc tgttttgcag gtattggctc
    16501 ctgtactact actgctcctt tagattctat ctcttccata gaaactacta catcacactt
    16561 tttagatacg tcatcagatt ctcctgttaa catatcttct ctaattttaa ggtttatact
    16621 ttctataagt ctaccatcag caggtaccat gtcaccagtt tcaatatata ctatatcacc
    16681 tggtaccaat tcactcttag aaatttgatg tacttcccca tctctcaata cttttacttc
    16741 tatgttttca gtcaacttag aaagagcctc tgctgctttc ttagaacgac cttctgtaat
    16801 catacctatt gctataccta ttgctatagc acctacaatc cctattgcat catgagtttc
    16861 cccaattact gcacttacta ctgctgcaat aatcaagata actatcattg gttcacttaa
    16921 actttctttt aaatcatccc aaaaactacc ctcttctttt ggagtaaatt cattcaaacc
    16981 atatttttct cttctagtct tgacttctga ttctgataaa cctttttcag gattaacaga
    17041 taagtctttt gtaacttctt ctttatctac attataatat ttgatatcat tattaaattc
    17101 catatgcaca ctcaatcctg tctaaatttt gcattacttc tttaagaccc gcatcttttg
    17161 ttccttcacc aattgcttta aattgccaac ttccatcttt tctatatata gctcctacta
    17221 taagagtagt tttttcagaa taattatcag atagattgta ttttgctatc tctttcttat
    17281 taccttggtc ttcaactctt atataggcat tttctatcat tccaaagtgt tgttttctat
    17341 ctacacaatt gtatatattt actacaaaca ataatttatg aatatttgat ggaactttat
    17401 ccaaattaac taggatttgt tcatcatcac ctgtaccctc accagttaga ttgtctcctg
    17461 tatgcaaaac tgatttacag gcacttttta gatttccaaa ataaattaaa tcttttattc
    17521 cacttaattt accttcttga ttaagcataa atacagatgc atcacaatct atatcagctt
    17581 gtcctccacc aaataacgat ttaaaaaaac ctcctccaga ttgttgcaca gggtcccatc
    17641 ctagacctac aagtatgtta ctcagtcctg ggttagattt ttttaaatct attttatcac
    17701 cttttgataa attaatcgac atactaaacc tccacaaaat tttatataat ataacctata
    17761 cattatttgt ataggttatt tatatttaat atattatatt gcttaaatta aacatttaag
    17821 ccatagtttc tacaaagtgc ttctaagcca ccttcaaatc ctgctccaac tgcactaaac
    17881 ttccattctc cattatactt atatatctca catactgtaa ttgcagtttc tatactaaat
    17941 tcttcaccta agtcatatct taatatttct tcatcatttt cagaatttaa tactcttata
    18001 tatgagttgc ttacttgtcc aaaattttgt cttctttcag cagcctcata tattgtaact
    18061 gttacagcta tcttttgtat atgctttggc attgtctcta aattcactaa tatttcctca
    18121 tcatctccat caccttcacc agttctatta tcacctaagt gttcaactgc tccagatgga
    18181 tgtcttaagt tattgtagaa tataaaatct tcatcttttt caactctttg agattctcca
    18241 accatgaaaa cacttacatc taaatcataa tcatagccac tatcaaatga atttgtatcc
    18301 catcctagtc caagttttat atttttaaga cctggatttc ccttagttaa atcgattttt
    18361 tgtccttttt ttaatactat agccatggaa aatatccccc tttagtttat tgttatagtt
    18421 gaaattataa gtttattcca aagtttccac ataatgcagc aagaccacct tcaaaaccag
    18481 aacctagtgc attaaacttc cattctccat tgtgcttata tatttcagct actactatag
    18541 ctgtttctat actaaaatct tctcctaatt catactttat taactcttca tttgtgtctt
    18601 tatctactat tcttatataa gaattactta cttgtccaaa attttgtctt ctttctgtcg
    18661 catcatgaat tgtaacagta aaagaaatct tgcttatttc tccaggaatc ttagataaat
    18721 caacaactat ttgttcatca tctccatcac cttcgccagt tctgttatct cctagatgct
    18781 caactgctcc agatgtatgt tttaaattgt tgtaaaatac aaaatctcca tcattagtaa
    18841 cacttccact tgctcctgtt aaaaatgctg ctgtatctaa atcaaagtca aatccaccat
    18901 catacttgtt agtatcccat cctaaaccta ctaaaatatt tttaagacct ggatttcctt
    18961 tagttaaatc aaccttttgg ccttttgata atgttatacc cataatttat cgctcccttg
    19021 ttaattttag ctaaacaaat cttgctaatt atttatcttt ttctttaatc atattataac
    19081 attttttatt catttgtgaa gaaaacttgc ttgatatttt taaaatataa ttaaaaaaat
    19141 gtttatattt cttacttttt acatagattt tacatacttt attaaatgta taaaagctat
    19201 gtttaatatg taattatata tcatttatat aaacaagtac atattttatt ttgaaactac
    19261 aaaattattg tactatattg ttttaagttg ttttataata gattatatca tcttattata
    19321 ggagaaaaaa tatgatttgt actattaaac cattaaagat ttcaataaaa aagtcaactg
    19381 aacctctaat tgaatttata tctgatacta cctataaaaa taagagttct tcatatatta
    19441 aagaagtcca ctttacaaga tatataggtg ttgatgattc aattgataaa tacatagaaa
    19501 aagttaaaaa tatagatact tattttttta ataatcctac aattccctat attagattaa
    19561 acaatctaaa aataaatttt gacaaagaac aaacagataa gatgcttaaa atttttaata
    19621 tttatgatag ttctaagttt aacagttggg atttatataa tatcgacttt ccatgtaaaa
    19681 tagaaaatga cactttaaat tggactaaaa agattgcatt taaaaatact ttagatttat
    19741 tttccacaag tatgccaaat tgtacatcct ctatcatcaa aaactttgca gttaaacttt
    19801 tgtgttggat ggactatttt ctacctaaat tattttataa caaggtgaag actactattt
    19861 caccaaagat agtatacttt ggaaatatta aaaggcaaga actttttttc ttatattttt
    19921 tatcacaact tgggtgtgat attttatata taaatccaaa taaagatatt cttgatttat
    19981 atcctgaatg ttcaaaattt tctactctat ttgaactttc taggaaaact ccaaatatat
    20041 tagaaatacc ttttgaaagg catattacaa atataaatta cagtgaaaat accaataaga
    20101 cttctcctac tacgaataaa cctaactcta aaaatacact taataacaca aatctaacat
    20161 ctaaaaaaat tgcacaagat gaggaagtag aactttctta tgaagacctt gcaaagttat
    20221 cagcttctgt tgttatgatt gttgtgtgca ataacgaaaa taaaccgttt aagagtggtt
    20281 ctggagtagt aataaataat gaaggttata tacttacgaa tcttcatgta gtcaatgatg
    20341 ggtattcatt tttagttaga tttgaaaatg atgataaagt ttatacatct taccaaatta
    20401 taaaatacca ttcagattat gatttagctg tgataaaggt tgatagaaaa tgcaaaccaa
    20461 tacctgttaa agtcagtaaa aaacctgtga gaggtcaaaa aatagttgca attggaagcc
    20521 ctttaggtct ttttaataca gtttcagatg gaattatctc agcttttcgt gattttgaaa
    20581 cggttcaaat gatacaattt acagctccaa tctctagtgg tagttcagga ggagctcttt
    20641 tagatatgtt tggaaactta ctaggattga tttccgctgg atatgatgat ggacaaaact
    20701 taaatttagc tgttgaaagt aatcttgtca aaatatttgc caataatttt attgagatag
    20761 taaactaatc aatcaaaatt ctacttatcc tattccataa taatcaagag ggtgaaaaca
    20821 ttgcatgctt ttgccctctg attaatattg aaaaaagtat taatactcga catttttatg
    20881 ctcaataaat aattgatgcc atagacaaaa tgtaaatata gtccatattt ttctcgaatt
    20941 atctctatga cctttaagat gcgtatctaa aagttttatt gcatattttt tatctataaa
    21001 ttcatctaca tttgaattat aaatagtttc ctttacaata tcccctagag aatcttttaa
    21061 ccaaactctt attggagttg gaaatcctaa ttttttcctt tgaacaacat attctgggac
    21121 tatttctcta aacgcctctc taagtaaaac ttttgtatta ttcttattta ttttttgctc
    21181 cattcttaaa ttttttgcta catcaaatac atctttatat aaaaatggta ctctaagttc
    21241 aacctgctca gctgtagaaa gtttgctaat tttttgaagt atatcgcctt gaagccatgt
    21301 attcacatct atatgttgca ttttacttat ataatcgtaa ttattttttt gtgcatctct
    21361 atacaaatta gacaacaggt attcatatat attcttttcc ttatacttaa aaaagaatct
    21421 ttttacttcg ctgttttcaa aaacttttgc atttcctata tatctttttt ctaatggtgt
    21481 tgtagctcta taaagataat ttcttccttt tatgtttggc ataagttctg aaactcttcc
    21541 taatatactt ttaatataag taggtgaatt gacaactgat ttcatagtac tatactcttt
    21601 atatatatta tatcctccaa ataattcatc tgctccttct ccagacaatg ctactttaac
    21661 atgtttacct gcctctttaa ttaagaaata aagacctact tctgaagggt ctgctatagg
    21721 gtcatccaaa gaataaatta cattcggtaa tgattttata tattcatctt gtgttatatt
    21781 aatctggata ttttctatac ctaacttatc agctgttttc tttgctactt ctaattcact
    21841 atatcctttg acactaaagc ctgcagaaaa agattttata tttggattaa tttgtgaagc
    21901 cacagtagtt ataatagatg aatctattcc accagacaaa aatgttccaa tttctttctc
    21961 ctcttccata tgagttacta ttgaatctac tactatattt cttatatcat cctcattcac
    22021 atctctattg cctaagtgat ttttagtata aaaaaatttt gtactacttc taaactcaag
    22081 tttattatat ctctttaaag atagtatacc attttctacc ctaaaatagt gacctgctgg
    22141 tatcagcctt attccttgta tcatagtatc ttcaggaagt acatattgaa atgaaaaata
    22201 actttgtaag cttctttcat ttatatttaa atttttcata tattcaagta aaaacttata
    22261 ctctgaggaa aaaattattg cattttcctt atttatataa taaagtggtt ttatcccaaa
    22321 taaatctctt gctccaaata tactttcatt ttctctatca tagattataa agttgaacat
    22381 tcctttaatc ttatgtacac aattcttacc aaattctata taagatgcca ataagacttc
    22441 aatatcatca tttgtagtaa aattgtgtcc ttttttaatt aattcttctt ttatttcatg
    22501 atagttatat atatttccat taaaaacaat aacttttcca tctttttcaa atggtttatt
    22561 tccataaata gcatcaatta cattaaatct ttcaaaatca aaagtttttt cctcatcctt
    22621 atactctatt ctactagaaa gtcttgtatt atttacagat tcttttattt taaatttaat
    22681 atcttctttt ttagatatat cacctttata ataaattgaa atattgccgt ccatataatc
    22741 aaaattcctt tctgtccttt agtcttattc tatatttcat agttttgtct ttggctttaa
    22801 aacttattca atttaaaatg aaattgctat taaattctta taaattatct gttaatattt
    22861 catatttttt ttatttctag aaatactata ttaggaggtg atttttatga agaaaaaaat
    22921 attaatacca gttattatgt ctttatttat aatctcacag tgcataactt catttgcttt
    22981 tacacctgaa aataacaaat ttaaggttaa accattacct tatgcatatg atgcacttga
    23041 accttatata gataaagaaa caatgaaact gcatcatgat aagcattatc aagcttatgt
    23101 tgataaatta aatgctgctc ttgaaaaata tcctgagctt tataattatt ctttatgtga
    23161 attattgcaa aatttagatt ctttacctaa agatattgct acaactgtaa gaaataatgc
    23221 aggtggagct tataatcata aattcttttt tgatataatg acgccagaaa aaaccatacc
    23281 ttctgaatct ttaaaagaag ctattgatag agactttggt tcttttgaaa aatttaagca
    23341 agagttccaa aaatctgctt tagatgtctt tggttctggt tgggcttggc ttgtagctac
    23401 taaagatggg aaattatcta ttatgactac tccaaatcag gatagccctg taagtaaaaa
    23461 cctaactcct ataataggac ttgatgtttg ggagcatgct tactatttaa aatatcaaaa
    23521 tagaagaaat gaatacattg acaactggtt taatgtagta aattggaatg gtgctttaga
    23581 aaattacaaa aatttaaaat ctcaagatta attaaatatt aaaatccttt tgaaaaaaac
    23641 ttatgtttgc tatataatat aataaaagat agtctaaatt taccaatata atgtttatag
    23701 tgacgattca ggaggatttt tatatgataa aagaaacaca tgaaagggga ggttatatat
    23761 tcgcactttt gatactcccc tttataaaca atctgtacct agttaaatac gatattgcat
    23821 ataaaatagt attaattata atttatattt attttgcata tttaggttct ttatttccag
    23881 atatagatat gagaggttct tacataagta aaaaatttat gttaatatac aaattatttg
    23941 gaagtaggtt tagacataga gggtttactc acagtctaat tgccttatta cttatttata
    24001 gtttttttaa atctctgaca atcttcacta acaataatat agttttctca tgtttgtcca
    24061 gtgggtttat aataggatat ctatctcact tgtgtcttga ccttattact aaagaaggta
    24121 ttgaattgtt ttatcccatt accataaaca tttctttact acctataaaa actaactcaa
    24181 aaacagaaaa attcatatct aagctattaa atttcatagt tatttttttg attggatatc
    24241 aattttatat tttattatag ttgtagaaaa aataaataac aatattttga actaagtata
    24301 aataagtttt atatatttta gtttacaaaa gaactaaaaa ttttgtacct taatacaaaa
    24361 aataaaacgt atcttaaaat aatttagtac taaatcattt taagatacgt tttatttcgt
    24421 acaagctaaa tcattttatc atctttatca ttgtgatgtt ttttatgatg gaaatcataa
    24481 ttatgatttt caagattttt atttactcta tttccaatct tccatgacaa aaacaccaat
    24541 aatataaatg atgctatctt taaaggactt gttataaaac cttctatatc acttgccacg
    24601 taacttataa ctataaacat tacaaatttt cctgccaaca ttgctggcac aaaatctttt
    24661 aaatcttttt taccaaaagc tgatgcgata gtaactaaac aaccaggcat aaatggacag
    24721 gcatacgcta taaataataa cttaaatccc tgtttatcca tccaacttat tgctttttca
    24781 gttttactat ttctcaactt attaaaaagc ttactatcat taaatctgct tattaataag
    24841 aataatgaag ttgtcccaag tcctgagcca atccatgata acaaacatcc aataaataat
    24901 ccttgtattg cagcatttgc tgtaactata gcaacaagtg gtaaggctgg tataaagctt
    24961 tctataaatg cacttaataa gccgattatt gtggctaaca cccaataatt ttgagtcaaa
    25021 tcaagtaatt cttgtatata ctgcatattg cttttcccct tttttaactt taactattat
    25081 tatatactct atatgtttat tatataccaa tctcaaaaaa tgaatctaat attaaaaagt
    25141 aaataatcta tataagttta cagttaaggt ataattattt tattatatat tataacaaaa
    25201 aaggtgatgt ttcaaaataa aaatctgaaa catcaccttt ttataactta aattgtcatg
    25261 taagttataa aaaatatata ttagacataa tattactaaa aatgtctagt cagagtaaaa
    25321 taaattacac agtacaacaa atattactat ttaattgagt tacttcttta taacatttaa
    25381 ccttcttcct actctgctca ataattcatt cgatatacta catgagttat ttgcaacttc
    25441 agaagcagat aattcagata aattatctct tcctattatt attgccgtat taccaacttc
    25501 tacattaggt atatctgtaa tatcaacagc aagttggtcc atgcaaattc gacccactat
    25561 tgctgctcta caaccattta ttattacgta actttttcca caggataaat ttctaggtat
    25621 accatcggca tagccaatag ataatatagc aattacgcta tctctgcttg caataaagac
    25681 tcttccatat ccaaaactat catctttttg tatttttcta ataagaatta cttgtgattt
    25741 taaggataaa acaggtcgta aatcaagttg caatttagtc gtatcatttg gagaacttaa
    25801 tatcccgtat aatgcaattc caattcttac ataattacac ttaagattgg gataattaaa
    25861 aaaaccataa ctactttgaa tatgtacttt aggaattttt ataccttttt ttaacagaaa
    25921 atcaattaac ttataaaaac attcaatttg tttatttgta aagtctacat cttcatcttt
    25981 cagactatct gaaacacaca agtgtgtaaa tatgccacat atatctaagt attttaattt
    26041 aaatgccttt aaaattgacc tcacatcatt aacatcaaaa cccagtctgt gcatacctgt
    26101 atcaatttta atgtgtgatt ttatgttgta tttctgtttg tttaaagaga tagcatgatt
    26161 aaggtcaata acactctgtg taagattgta tttatgaagt tcctttgccc ttattgggtt
    26221 agtatatcca agaatcaata tttctcctag tattccatat cgacgtaaat caatcccctc
    26281 atctattgtt gctactgcaa atgcttttac acctatttgg tttgcacaag tcgctacttc
    26341 aaaagcacta tgaccatagg cattagcttt tacaactgcc atcaattcac aatcttctgg
    26401 catagctttt tgtatcatct ttacattatg ttccaaatta tttaaatcaa tttcaatcca
    26461 agctctattg gtatttacct tatgttctcc tttcaagtct ttttttagag gtttaagaat
    26521 caatataata attatagaag ctataaaaga tgctatactt accactatat aatgaataag
    26581 gctattgtca accaagacag tttgtattcc gaatatttta gaaaacatac gaataacaac
    26641 aatcatcata ggatgtataa tataaataat taatgatgat gttcgcaata acctagctcg
    26701 agaacctttt aaaaatgtta aggctgtaaa taagaaatac atacatggca ataacataat
    26761 atacatgcta tcatgacgct gtacccctag tttatgtaaa aacattccct cacataacat
    26821 aagtaagaat gatataagaa atccaatcaa gctattttta gttgacatat aattagattt
    26881 attagatatt attccaccaa gtatgaaaaa tacaggtgca aaaaatatac catttcgtgt
    26941 ataatctgat acttcaaaaa tatacccata taaattcttt aatagtggta ttttttctaa
    27001 aaaaccataa taactatcac caaacatacc aattacataa ataacaatag tgattactaa
    27061 tgagtacttt aaacctagtt tttttacaag aaagtatgca atacttgcac caataattga
    27121 tgcaggtaga taccataaat gatataaagt cccatcaaat acaatgtcct taataatatt
    27181 gggcactaaa ttattcatgg aaaaatatcc agtgtaaata tttaagggaa tataaattac
    27241 aatagctatc ccgtaaataa ataatacatt ttttagaaaa gatttcagtt tattacaatt
    27301 ataattatat gttgaaatta gaaaaaagcc tgatagcata aaaaagaatg gcacagcaat
    27361 acgagcaatt atactagtta acacaaagtc agccatttta ctatatgata ataatggaga
    27421 tgtatgaatt gcaattataa gtaatgcagc tataatccta aaataatcaa gccctgcata
    27481 agatttattc ctaatcattc ttgttcctcc atttcttagt cctttctatt tctccaaaat
    27541 gtcacaataa aaccatcctt attgttaccc gatatttgat atacacattg ttcaggtata
    27601 gagattctca cttcttcttt agtatgaata ggcacataaa agatttctat aattttttct
    27661 ttatcttcta tttttaaaca atttgtatac gaaaatctct taatatattc tatatattct
    27721 tcaagggcga gattcatttt attgataatc tcagaatgtg gatatccgac ataacgaaaa
    27781 tgccatggtt cttgagatat tcctgttatt tcttcttttt tacactgata acgctctata
    27841 aaaccataat gtagtgctgc cttacggaac tcattacaaa taccattata aggaaattca
    27901 gggcagataa aatctataac ctctttcttc aaccctaaat caatagcaag ccctgtctga
    27961 tgttcactgt gatttggaag tgctacaaac tttttagtaa agtcttttcc attgtcacgc
    28021 agagagcttg aatatatatc ttgttgttcc tctgcagtac gatatccact tacaggtact
    28081 atttcattta ttccacatat actttttaaa atattttgta aaatatttgt agcttcacgt
    28141 ttcataagaa tacttggaaa ccttgtatct acaggaatta aatctatatc ttcagatgtt
    28201 ttaactggta aaaaagcatt tactagaatt agattcccat cataaacttt atctttagtc
    28261 aataagatag tatttgtcat tttatcttct ttatttttat ctaataaaat attattcatc
    28321 attttatgta cacctcaatt atcttatcca atatttcttc aaaagacagt ccaatacctt
    28381 tcatcatatt cggataacga ctatgagaag taaagccagg aattgtattg acttcattaa
    28441 aaataatttc accagatgga gttaaaaaca tatctactct agcaaatcca gaacatccaa
    28501 gagttctata aataattttt gctgtctctt gtattctttt ctcacaatcc aaatcaattc
    28561 tagctggcat atgaattttt gaacttttca atgtatattt ttctgtataa tcaaaaaatc
    28621 cttttgacaa ttctatttca tctactcttc caacaagtaa gtcatcgttt cctaaaactg
    28681 cacaccctac ctcaaaacca tcaatatttt cctcaattat tacttcatta tcatgttcaa
    28741 aagccaagtc tactgctact tgtaactctt cttttttata aattttacta ataccaaatg
    28801 atgaacctgc acgcacaggt tttataaata atggataagt taagtctttt gacagttcag
    28861 ccacattaaa tttatctgag tattttagta atattgattt tggtacttta ataccttctg
    28921 aatgaacaag tttatgtgat ttgtctttgt ccatacataa tgctgaagaa agagtaccac
    28981 atccaataac ctgtatacct gccaattcaa ataacccctg cactgttcca tcttctccat
    29041 tttttccatg caatacagga aatacaaaat caagtttagt gtatttaata tcattttcac
    29101 atgattcaat agcactattt ggaatatgat tctgagaaac agcatcagga attaaaaatt
    29161 caataatacc atttttgaca cggttctgcg aaacaataac tggaattata tcagtatccc
    29221 tttcaaacca agtgttattc tggatattat tataatctcc aatataatga taccaattac
    29281 cctcccttgt aattccaatt ggtataatat catatttttc cgtattcaaa ttctcaagta
    29341 ctgcaaaagc tgattgtaat gatacatcat attctgttga gtttccacca aatataactg
    29401 caattttttt attattcatc tttgattctc ctttgttgat ttatttattt ttatacaatc
    29461 tacagaaaca tgttaaaata ctttttctat ttcaaatcca atcaaccttc acttacaatt
    29521 gcatctgttc cacataatat attttcacat ttttctattg atataattac tgtatcaaaa
    29581 taaaagcact cttgttttga tacagtaatt atatcaataa caagagtgct ctttatttat
    29641 cctaaagaat ttcctatttt tttatactta aattcttaca aatttcctac aatcggaata
    29701 ataaccttaa aggtaattat attgttctcg ctatgagctg ttattgtccc gttatgaagc
    29761 tccactattt ctttagctat agcaagtccc aacccagctc taccactgtt tgaattacga
    29821 gatgtatcca acctgtaaaa ttgttcaaaa atacgctcaa gtttttcctc tggaatcgta
    29881 ttgctatgat ttataaattt aagctttata taatcatcct cctgtacagc tgttatttca
    29941 atagtagtat cttcaaaact ataataaaca gcatttcgta ataagttatc aaatacacgt
    30001 tgcattttat taacatcaca ccttatcatc atatttggtg taacattcag tgtatatttt
    30061 aaattcttac tcatcaaagt aggtttaaac tcatatgtta gttgttcaag catacgagtt
    30121 aagcttactg tactgtattc aagtgatata tttgataaat taaaccttgt aatttcaaag
    30181 aattcattaa ttaaatcttc aagacgctct gccttatcca acgaaataga taaatatttt
    30241 tttcgcagtt cttcagaaat ctgactttca tctcgaagta gtgtcagata ccctataact
    30301 gatgtaagtg gtgtttttaa atcatgtgca agataaacaa taagttcatt cttacgttgt
    30361 tctgccattt gtgtctcaaa tttacgttgt tcaagtatat gtttaattga gtttattttc
    30421 ttttctattg ccaataactc tggagataaa gccacttctc caacatcttc tttgataaga
    30481 gagtcaatac cttgatttat ttcactaaaa tattttgtaa accaatttaa ataaacacgg
    30541 aatattataa aaaacacaat caccatagct agtatcatga agagctccat gctattacgg
    30601 aaaatctgct gatataaatt caatgcagct ttatattcca tacgaaaagc attttcaaag
    30661 aatgatacta tccagataga aaacttacca tacaatataa aagaatataa aatccatatg
    30721 aaaataatgg ctataaatgc cattaaagct gttctcataa aaattttatt tctcacttga
    30781 gtaaagtcag gattgacttt aatattttta cttttcaatt gtataaccta ctccccatac
    30841 agtttttata aatttcgggt ttttagaagg ttcatgaatt ttttcacgta atcgccctat
    30901 atgagccata actgtgttat tattatcaag atatttttct ccccatacag cttcaaacaa
    30961 ttcttcagaa ggaaccactt ttccttgatg ttcacataaa taccaaagaa tagaaaattc
    31021 aatcggtgtt aatgctactt ctttcccaaa taaactacat ttatgtgttt ctttattgat
    31081 aatcaatcct ttaatatcat actcattaac aattatcgac tgttgttcat aagaattatt
    31141 atatcgcata tatcttctta attgtgtctt tactcttgca acaacttcca aagggttaaa
    31201 tggctttgtt atataatcat cagcacctat ggttaaaccc attatcttgt ctatatcttc
    31261 aattttagct gttaacataa tgataggata atagtatttt tctcgaattt tctggcaaat
    31321 atgaaatcca tcaatatcag gaagcataat atctaaaata gccatatcca aatctttaga
    31381 ttcaatacat tctagagctt ccttacctgt ataaaacttg tatactgtaa aaccttcatt
    31441 ttttaaatat acttcaatta aatctgctat ttctttttta tcatccacaa tcaaaatatt
    31501 ttcgttcata gattattttt cactctcctt attatcgagg tcatcattta taatattggt
    31561 aaatttacat atcaaataat tacaagcata tttgtaacta atttttataa gaaaagaact
    31621 actacatcag aatgtgttga tgctactatt ggaacacaaa aactgagatt aattgttatt
    31681 ataaaaactc ccctaacacg tccttattat cgcataacag gtattaactt tcaataaaaa
    31741 tatctatcag tcaaacacaa ttcaatttat tataccagag acaatccata taaaaaacaa
    31801 ttaaacctat gtatgtaacc acagacatta ctaaaatttc catgttattt tatataaaaa
    31861 ttcaaaaaag gagttgaatt taaaatttga ttagaaaaaa atcaattttg agacaactcc
    31921 tttttatttt aatgtattta aattatagta tatcagcctt cataatatcc tcaaaatcac
    31981 ctttttcaga tattaatctt atcaatttaa cagtacagct taaatcattt ataagtatag
    32041 ctccaactaa tgaaccatct ttcataaata attttttata tattctttga ccttcatctt
    32101 ttgatgaaat ttctttatca aaattttgta tattaccaat actaaatact tttacattca
    32161 ttgcatctaa tgaaactgga tatacttcac tttcaaatgt caaattatct ccacttgcat
    32221 ttgctcctgc tatttttccc atttctactg aagatggcca tattgctaaa ctaatatttc
    32281 ccacttgtgc aacatctcca caagcatata tatctttaac atttgtctgt aatgtcttat
    32341 ctacaacaat acctctatca atttttacag atgtatcctg aaccatttga gtgtttgctc
    32401 ttacaccaat tgaaaatact accatatcac agtcaacact atctccatct ttaaatacaa
    32461 ctttttgagc ttttccatca ccttcaatac catcaactgc tacacccaat cttacatcta
    32521 ttcctgtatc tcttacacat tgttctaata ttttactacc ctctttatca agttgttttg
    32581 atagtatgct atccatggct tcaactacta ctacttctaa tccttttagt ctaaattccc
    32641 atgcagcttc aagtcccaat aaaccgccac caatcactac aactttctta gatttttcta
    32701 gtgcttcttt tacactatat aaatctttta tatttctaag agtaaacaca ttttctaaat
    32761 catggccctt aatcggtggt ataaagtttc tacttcctgt agctattaca agcttatcaa
    32821 atttaatagc tccatcattc actataatag ttttattcac ttcatctaat ttatctacat
    32881 tcgttcctaa tattactact atattatttt tatcatacca atctttatct tccatgtaga
    32941 aatctgaacc aagttcttca tttataccat cagaaagtgc aggtctatag taagtcaact
    33001 catcttcatt agaaatcata gttatcttac aagttttatt tctttttctt atagcatctg
    33061 ctgcataaaa accagctgct ccatttccta ctattacgaa atattcatca gtatcttttc
    33121 taaaagtaac ttcatcttct tcaacttcta taaattggtc ttccttagct ccacatacag
    33181 ggcatacact aggagcacta tcaccttcaa aaacttcatt acaaattaca catttaaatt
    33241 tcttagtttt ctttttactt ccaaaagtag aatttaactt atctaggaat ttacctgtat
    33301 aagaatgtaa tttatcaatc tcttcatttg atggtttaaa gttaacagca aaaggtttta
    33361 ctgctgtcat tctaagctga cttattctct ccatagcatt ttctatacct tctccactcc
    33421 atccatatga accaaatact gaagcaactt ttccaccatg aagaactggg tttaacgata
    33481 ttaatatatc ccatataggc tttaacgcat ctcctaatat tgttggtgtt ccaaataata
    33541 caccttgtga tactgctatt tttgccaaaa tatcttcttg cttatgctct attacatcaa
    33601 ataaatttac tttatagttg ctattttttt caatatatgc ttttatagct tctgccataa
    33661 tctttgtata tccatgtgca gaaacataac aaattgtaac ttctttttct aactttattt
    33721 gttcctttac actccagtta taataaaggt ctataatttt tctaggattt tcagttaata
    33781 ctggaccatg acctggacat acagtatcta tatctaaatc ttttatcttt tctatagcag
    33841 ttaccataga tggtttaaat ggacccatta tacaatcata atagtatctt aaagcatcca
    33901 agtaatcctt ttcttcattt tcatcaagtg tatttactat cttatcatta ctatagtgac
    33961 taccaaatga atcacatgtt acaagagttt tatcctcttt tatatatgtg tatatagtat
    34021 ctggccaatg aagcataggt acagagaaaa attctaaagt tttgtcccca attgataatg
    34081 tatctccatc tgtaactgca acatattcaa agtctttgtt tacgatttcc ttaagatatt
    34141 taattgctgt ttctgaagct actacttttg catttttagc taaatccaaa agcttttcaa
    34201 cgcttcctgc atggtctggt tcagtatgac ttacaacaat atagtctatt ttttcaaaat
    34261 ctatatttaa atcatttaat ctttcaatat aattgtcaaa atgcttatct ttaactgtct
    34321 caaacaaaac tgttttttct gttcctttta atacatatga attataagta gttccataag
    34381 gtgtatacat aattatgtca aatactctta aatcagggtc aagtgaacct acccaatata
    34441 aattttcttt tatttttagt gatttcaatg acataccgta ctcctcctaa aatagttatt
    34501 tagtctcttt ataccctgct tgttatattt taaacaaaat ttattcaaaa aagaaattat
    34561 tttaaagata gtttaaatct tctaatcttc tttttctacc ttcaatacag ttcccttttt
    34621 agaatctact tttatgtcat attcattttt atctttatct attcttattt tataaaaagt
    34681 aacatctaaa tctttgtcta aactccattc tttaaccatt ccattttgtt cttttaatgc
    34741 aatttccata gcttgttgag gtgtaattat gtcatttaaa tctaattttt cttttctagc
    34801 aactccattt aaatcttctg aatctaactt ttctgtttta tcttctaata catcttttgt
    34861 attagcatca attttcatct tatattcatt attatcatct acaccttcca cagtataaac
    34921 aaatttattt aaatctctct caagacttaa atctactata tcagcatcct tgtatttatc
    34981 tttaaatatg tttattgcat ctgtgtatgg cactttaaaa tcttgttcca ttaaattttc
    35041 attatttttt tcatctttta aagcattatt tgaagcattt gcctcctttt ttgtattatc
    35101 ttgtgcttgt cctgaatcct tagttgggct cccactacat gcagttaata aacctgctat
    35161 aagtatactt accactaata aatacgtttt tttacacata aaaatcctcc ttaaatatat
    35221 taatttattc tatattatgc cctctaaacc ctttatttac ccttttatat taaaaattcc
    35281 tcctatttta tcaattttaa aactttatat ttactaaaat taaagttaca taaaaattat
    35341 actgtctcaa aatagaaaca agcatctttt tcattgttga aataataaaa atatatttta
    35401 tttcgtacaa aaagagtgcc tcatgaacta aaaagttcat tttgagacac tcccattctt
    35461 ttatattttt acttacaaaa taacagtact tattaatttt ttacaaacct tataagtata
    35521 tctatattat attcttaaat ttaaacacta tattaaaaaa ttaaattttg tttaattctt
    35581 ttactgttaa atccatttta ggatatggaa tcgtaattcc ttcttcgtca aacctaactt
    35641 taacctcttc tagtaaatca agataaattg tccaataatc ttctgtcttg caccaaactc
    35701 tagttgcaaa tttaacagca ttatctccat gttctactac tcctataaat ggttctggct
    35761 catttattat taatttatga ttattaacaa tatctttaag tactcttcta acatgtagta
    35821 tatcatcttc ataccctaca ctaaaagtca aatcaactcg tctagtattc tttgctgaat
    35881 agtttattag actatcattt gatacagaac cattaggtat aagtatctgt ttattatctg
    35941 gagtaaccaa ttgtgtataa aaaagtccta tttgttcaac cgttcctcca tggcctgctg
    36001 cttctacgta atctcctact ttaaaaggtc taatcaatag tataataaat cctccagcaa
    36061 aatttgatag actaccttgt aaagccaaac ctattgctac ccctgctgat gctatcacag
    36121 cagcaaaact ggacaaactc attccccaat attccagaac aatgattata acggcaactt
    36181 taagtacact caaaagaaga gacttcaaaa accttcttaa agttaaatca atatctcttt
    36241 tactaagtac taacataaca tggtttacaa atttttttat tattttaaat ccaatagaaa
    36301 gtataagtat acctattata agttttactc cgcttgtagt agcccattct agcagacttt
    36361 ccattatacc tcccatatcc atcttattaa tgtctaaatt atttaaatct aacttgctta
    36421 tatcatctat tttcgtcgta tccataaaaa actccttacc ttatatttta gaaccaatat
    36481 tatagtttaa agttcttatt ttctatttaa tataatacaa taccatttgt acatagtaaa
    36541 caagatttat attccaatta tacatcttag gaaaatgcaa actatttgtt atatatatgc
    36601 aaaatataat actaaattaa actattaata aaacactata tagccttaca atcatcattt
    36661 tttaccccta tatgagatga tactatagtt ataatactta gtactataaa tactacaaaa
    36721 ccttttttat atccatcaac tatattatat gaatttactt gtaaagagat agctataatc
    36781 aaattaataa ttccacttcc tataaattca aaagtattaa taacactagt tgccagtcca
    36841 gaataaattt ctttattttt atacttggca tcattaaaaa cctgtagatg tgacataact
    36901 atacatccca taataaagaa tgatattggt aaaactataa ttggtggttt tacctggtat
    36961 acaactacaa ttacaatcca tataaacaaa tctatcattg ctccaaattt tattatatta
    37021 aatttgctag accttatttt agcaaataca aaatccataa ttattgaacc aaatataaat
    37081 ccatatgtaa aaaatgatac tataaacgca gaaaaactct tactcacacc ataaacgtcc
    37141 attatgtatc ttactcccca caagcttata aatgcacttg taagaccaac aaaagagaac
    37201 attatcattg aattatacca tgttgatttg ttctttataa cagacttaat accatcaaca
    37261 atattaacct tctctgactt ttcatagggt tcagtatcta cattgaatcc atactctttt
    37321 ggtgtatctc taacaataat atatataaaa catccaatta caacaccaat tataccgatt
    37381 aataaaaatg aatttctcca accaacaagt tcagacaaaa acacaagtgg aaaagtagca
    37441 agaactccac ctaaatttcc tacaaatgaa aatttagctg ttgcagaagc aaattctgac
    37501 ttattaaacc atctcccttg aatttttaaa atacaaagta atattactga tgttcctgcc
    37561 cctacaatta cacgagaaat atatgctaat tctatacttt gaatcaaacc aaataaaatt
    37621 gaccctaaac ttgccattat tattccaaga ctgctaattt ttcttgctcc atatttatca
    37681 atcaaaattc ctgcaggtat ttgcataaat gcatatgcat ataggcaaaa ggatgctata
    37741 tttgaaattt gtatagaatt aaaacctaac tcatttgcta aattgtctga aacaacagca
    37801 gttgacatcc ttaaaaataa tactaaaaca aatgaaaatg taattatacc ccaaacactc
    37861 cacttagcct ttgtataact tttcatatct tctccctcaa atccatatat ttttaaattt
    37921 tcttgatata acttatataa agtgtatagt tattcttaca aatttttaca cgcaatatca
    37981 ttatacaaca tatgtatata tttaactaga aataaaatac tattcatatt atatacatga
    38041 attaactaca taaataataa gagccatctt ttaacattac tcaaaagatg gctccatata
    38101 aaaacattta ttctaaattt aattttttat ctaatataaa ttttgtagcg aaaaataacg
    38161 ctattgcaac tacaagacta ccaagtattg caagcataaa actaggactc tgataaagat
    38221 gatataccat atttgtatct tcatttggta agatgcttcc aactgcatct ccaacaattg
    38281 atattactat atttatagct ataaaagaag caaatgccac tatgtttcta tgtttattga
    38341 attttggtaa ttgtcccatt gagattgatg tatataataa caaaataaat gatgaatatg
    38401 aaataaacat tactactact aataataaaa tatctaaaaa gttttcagaa atccatttaa
    38461 aactagtgtt aaacaaatct aaaatttcag gtagtaaaat tccagaagta ccaaaaagca
    38521 taagaactcc aaaagtgaat actgcaacta taaaactaag tacagcgtat ataagtgctg
    38581 ttatacattt agataatata agtgaactag tgctaacagg aagagtaaac attaaataac
    38641 cttcatcccc caaaagattt tttctaaacc tttgaattgt aactacaata gttaaaactc
    38701 ctaatgccat aaaaagactt gttaatacta gtattcctat tccctgtacc tgaagtatat
    38761 ttgtattcat aaatattcca ttaaatacag ctactatcaa tatggctata tataacggta
    38821 taaatattct tccacttgct tttaactcat attttaataa tttacctaac atttaaattc
    38881 ctccctaaat aatgcatcta tagattttcc tttttcttct cttattgctt caacgtctcc
    38941 ttgtaacact atttctcctt ttgatatgaa tattatctca tcacatatgt tttctatttc
    39001 acttattaag tgggtagcaa tcagtaaagt actatcttca gaataatttt ttaatatagt
    39061 cttaagtata tatgaccttg cagctgggtc aacaccacct ataggttcat ccaatatata
    39121 tatgctcgca tttcttgaca ttactaaaat aagttgaact ttttctttag ttcctttaga
    39181 cattgtcttt agcttttcat ttacatcaat atctaagctt ttaatcatct catttgctct
    39241 tctaacatca aaatcactat aaaaatcata gaaaaactta agtaaatctg ataccttcat
    39301 ccaatcattt aaataagttc tttctggtaa atatgaaact atttttttag tatctatgga
    39361 tggtttcatt ccatttatca taatttcacc attatcaggc tgtaataatc cattcattag
    39421 cttaatcatt gtacttttac cacttccatt aggccctaac agcccgacta tttttccctt
    39481 tggtatattt aaatcaatat tttttaaaac attcttagtt ccataactct tgtttacacc
    39541 tttaaattca actattccat cttgagaaac attgcttata tttttatcca ttttataatt
    39601 ctcctttcag attttctgta ataagtttta gcatttcatc tctatcatat ccaagctttt
    39661 ctaaggttac ttttaatgta tttatctcca cattagctat ttcctctttc atagctttta
    39721 ttttttcctt atcatctgtt acaaatcttc ctttagttct ctgactataa actaaacctt
    39781 gtctttcaag ttctgttaga gccttttgca ttgtatttgg attaacttcc gcatcttctg
    39841 ctagtgctct cactgtttct aatttagatc ctattttaat ttcccctgaa attattttta
    39901 actttaaatg ttctactaat tgtatatata taggtttgtt attatcaagt tcccattcca
    39961 tgttcatgcc tccttattat attattgtat taatttatta atacaataat ataataatac
    40021 aaagtatatg tcaattactt tttagtaaaa gtataaaaaa tttcacaaaa aaaatgaaca
    40081 ctacattaga gtccattttt aacacaattt attaaattct ttatattaca gattaattac
    40141 cctcttacca agttggatac aattaaatgt tcaaattctt caattggcat tggctttcca
    40201 aacaaatatc cttgtgccat atcacacttt acttctttta aaagtttaaa ctgttcttct
    40261 gtctcaactc cttctgatat gactttcata cccaactctt ttgccatttc tattacttta
    40321 gtaacaatta ttttgcttct tttactatta taagtttcca taataaattt ttggtcaagt
    40381 tttaagatat ccataggaat ttcttttaac atatttaatg atgagtaccc tgaaccaaaa
    40441 tcatccatag atattaaaaa tcctattttt tttaaattat tcattatatc aattaaaata
    40501 tcaaaattat caaatatgat actctccgtt aattcaagtt ctatatactt tgcaggtata
    40561 ttgtatttat caattatatt tttgtatgtt tctataaaat tattgcaata taaatgtatt
    40621 cttgaaacat taactgaaac agtaactgga tttattcctg catcaatcca ttttctaagg
    40681 tatatacata cttcttcaag cacatataaa tctaaattta taacaaaacc gtttctttca
    40741 aaaaatggga taaattcatt tggaggtatt agccctttat caggacgttt ccacctaaca
    40801 agtgcttctg aaccttgtat ctctcctgta ttaagatcta tcttaggttg taagtatata
    40861 ataaactctt tattttctaa acttgaaaac attgtatttt ccatctcttt ttcttttatc
    40921 tcttggtcat gaatcttatt atcataaaat gcatatgaac ttttatgtcc tccctttgcc
    40981 attttatgag gtatattagc cctatctatg attgagttga tatctctatc ttctggaagt
    41041 ataaaataga ttccacaact taaaactaac ttatactttt cttcttgatt attattaaac
    41101 aagtctaatt cctcaaatat agtttttaac ctctttgtta tatcttcttc ttctatatat
    41161 ttcataatta taataaaatt atccgcagat attcttgcaa acatttcctc ttcaaatata
    41221 ttactcttaa taatttttgt taaattacgc aaaatttcat tcccaacttc atatccaaat
    41281 aaatcattta tatatttaaa tttatcaata tctatatata ataaagcata ctttacttga
    41341 gtatttttac atagtatttt gttagcatca attacaaatt tatctatagt atttgctcct
    41401 gtaagattat ctgtatatgc tatcttttgc aatttaattt taaaatttaa tttgtcatat
    41461 attatataga atataagcat catacatatt atagccataa taagtattat ttgtattgca
    41521 tatttgctaa taaactgatt attagacaca atagactcaa agttatttat ggagttgttt
    41581 ttatagagtt tgcataaaga atagactggt gttgtgtatg taatttgtaa aattatacaa
    41641 ataaataaaa aaaacatcaa ttttttttgt aaattcctca taaaaatttc ctcccattaa
    41701 aacacctcta ttttattagc aaataagtac atctcaaaag tttccatttc ttgtaaaatg
    41761 gatagtttat atctacttta attttgtaaa attttctgct actataatta tagaatgtag
    41821 catattcatt gtcttaacta ttgatttata tatttcatat aggtataata gaaaataaat
    41881 tggattattt tggcatataa ttatttatta aaaggtgatt atttttgttt gaattgtctg
    41941 aaaaatttta tttttatatt ataattttaa tattttcttt tc
//
LOCUS       DAMJYN010000033        39468 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.034, whole genome shotgun sequence.
ACCESSION   DAMJYN010000033 DAMJYN010000000
VERSION     DAMJYN010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 39468)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39468)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39468
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.034"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            202..1092
                     /locus_tag="PC466_001810"
     CDS             202..1092
                     /locus_tag="PC466_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HDF2769197.1"
                     /translation="MSSTIKSNRIKGIMFIIASALGFAMMSAFVKLAGDLPSFQKVFF
                     RNLVSAIIAFWLIIKHKGSLTGKKENLKVLLYRSIFGTLGVIFNYYAIDKLMLSDANM
                     LNKMSPFLVVIFCAIALKEKINVKQIGAIIIAFIGALFIIKPTFSVEVIPYLGGIAGA
                     VFAAMAYTCLRVLGDREDYYTIVFFFSVFSLVTVGPIAFAVYEPMTLMQLIYLLLGGV
                     FASLGQFGITLAYKYAPAKEISIFDYSNIIFSAILSIFLFNVYPDMLSVVGYLIVFSA
                     AFYMFLYNKKLDKLDKEKKK"
     gene            1310..2596
                     /locus_tag="PC466_001811"
     CDS             1310..2596
                     /locus_tag="PC466_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HDF2769198.1"
                     /translation="MEKVKVAVIGAGNRGTYAYAPYIYENSDICEIVAVAEPKKGRRE
                     LFTQKYNLDSKNVFETLEDFFKHDKMADAVIIATNDDRHYDVAKLALEKGYHVLLEKP
                     MSNSLDGLVHIDDLCDKYKDKIFMICHVLRYSPFYNKLKEIVESKKLGELVSIQYNEN
                     IGYWHFAHSFTRGNWRNSNETSPLILAKSCHDMDILLYLVGSRCKKISAFGSLKHLNN
                     QNASGEMAQNCLQCLVEKKCPYSAKRIYLEKDRSINRAVHINPTEENLLNILKTSPYG
                     RCVYRCDNNVVDNMVNILQFENGVTATFNLCAFTKENGRTIKLMFSHGEVGGDLNKNE
                     IRIKKFGKNEEIVMNPSNQQNMVEEYDRNLIAEFIKLVSNKELEKGRVAAKEAIQSHV
                     MAFAAEYSRVSDEVVYIEEFFDSAKQMTKEIEETIF"
     gene            complement(2685..3128)
                     /locus_tag="PC466_001812"
     CDS             complement(2685..3128)
                     /locus_tag="PC466_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="regulatory YrvL family protein"
                     /protein_id="HDF2769199.1"
                     /translation="MIKISNKRRIPLGEFISVFLFFAVFFGITFCIFTVIGIGFLSFL
                     GFEYKSLGAVLIFFLIYFCITTPIDFLCTTILDIFRYVNKLPYSIYKLCEFIIDFILT
                     FLAMNIIDTFMDSVTIPLSTEILFALLSYLLSECMDFFDRDKKKP"
     gene            complement(3152..3946)
                     /locus_tag="PC466_001813"
     CDS             complement(3152..3946)
                     /locus_tag="PC466_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M55 family metallopeptidase"
                     /protein_id="HDF2769200.1"
                     /translation="MKLYLSADIEGTCGIVNWDETKLECEFSQHYRTQMSKEITAACD
                     GATQSGVHEILVKDAHDSGRNINPNILPENVKILRGWTKDPLVMMAGIDESFDACIFT
                     GYHSGATCNGNPLSHTMDIDYDYFKINDEIASEFTINAYIAAYYNVPVAFLSGDEMLC
                     ESAKKLNPNIVTVPVSKGIGNGSISIHPNLALKKIEKGVKKALSGDLSRHLIKLPDKF
                     KIEIKFREHYKAFKASFYPNMKKIDSQTVLFETEDYYEFLRMLLFI"
     gene            complement(4512..4988)
                     /locus_tag="PC466_001814"
     CDS             complement(4512..4988)
                     /locus_tag="PC466_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HDF2769201.1"
                     /translation="MKEILINPIGKICIQGEEVFIKLDKKYVPALNELDDFSHLNVFW
                     WADGFDNPELRSILETPKPYKSGPNVIGIFATRSPIRPNPIALTAVQIINIDHENGII
                     KIPYIDANDNSPVIDLKPYTPSVDRVENPSVPKWCSHWPKSVEKSGEFNWEDEIEF"
     gene            complement(5089..6258)
                     /locus_tag="PC466_001815"
     CDS             complement(5089..6258)
                     /locus_tag="PC466_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2769202.1"
                     /translation="MLNIRTLCHEINDWIINIRRDLHKTPELGLEEFQTKKKIIKYLN
                     EIGINYIEYKNHTGITAYINVSPNFETVAIRADIDALPITEELNYSYKSINIGKMHAC
                     GHDAHTAILLGTCNILFKLKNYLNVNVKFFFQPAEETIGGAQLMIEDGCLENPNVKYI
                     FGLHVNPNINKNLIELKYNTLNASTDTLQLTVHGSKCHGAYPHQGIDAIVISAHIITA
                     LQTIVSRNTNPTDSVVISLGKIEGGIKENIVCDKVVIRGTLRTLTPETREFSKKRIRE
                     ICDFTCKTFGGSISVEIEEGYPALINSNHLVDYVKQNAVELFGEENIILKDSPTLGAE
                     DFSYFLRHCEGAFYHLGCANREKNITSPLHTSTFDIDEDCLITGVMLHVKNVLSF"
     gene            6421..7284
                     /locus_tag="PC466_001816"
     CDS             6421..7284
                     /locus_tag="PC466_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HDF2769203.1"
                     /translation="MLGIIAPSGPLRNTSLEEIKFNLESYGYEVKFSESCSLNYKGYL
                     AGNDDIRARDIEDMFLDKDVDIIMCLRGGYGTTRILDKINYDIIKQNPKPFIGFSDIT
                     GLNLAFYKNCGLLPYHGIMAANVGKWDKFTYKSLVNALEFKDDLYLENPKEEKIYTVC
                     EGKAEGIIMGGNLSLIIATMGTKYEIDAKDKILFIEEIGEPQYKLDRMLTQLYSSGKL
                     EECNGIIFGDFKDCIEENDLMELLIEFANKVNKPSIYNLQSGHCIPMITIPLGRMCEL
                     DATEKIVKLKK"
     gene            7355..7948
                     /locus_tag="PC466_001817"
     CDS             7355..7948
                     /locus_tag="PC466_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3867 domain-containing protein"
                     /protein_id="HDF2769204.1"
                     /translation="MSDDRIIDFNELKNKVKDSDVDKFEQYIYNLYFSVMDGKMSMAE
                     FSRKIFDYMRDNNISQEKFMKIQKQFMERYGMDTEEVEKQLRNFGIDPSTAGFMSNNT
                     SSKVSTEDLESFKKSAGFYEKYGEKIQPKSCITTFIKNDLNDINVIIDQEKIMLCSDR
                     KINLMDSELNEFLLEYKNMFNKKIKVVMCETTNKYDY"
     gene            complement(8199..8834)
                     /locus_tag="PC466_001818"
     CDS             complement(8199..8834)
                     /locus_tag="PC466_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HDF2769205.1"
                     /translation="MDNLLNELEALKSNLDNLPIEKIENYDLSKTALFIIDVNNGFAR
                     QGALYSPRVESLIKPIEMFTKKISNKLNRVIAFTDSHTPKSIELLSYPVHCLENDVES
                     ELVDELKSIENLQILPKNSTNGFFALENLDFDNIDNIIIVGDCTDICIYQFAITLKSY
                     FNQHNIEKNIVVPMNLVDTYDIPNIHPAEILNLVFFNSMIQNGVNVLKEIR"
     gene            complement(8914..9645)
                     /locus_tag="PC466_001819"
     CDS             complement(8914..9645)
                     /locus_tag="PC466_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HDF2769206.1"
                     /translation="MNIYAHRGFSGKYPENTILAFKKCLYMDIYGIELDVHRTKDGKI
                     VVIHDEKVDRTFNGHGFVKDFTLRKLKTLNSSFEGYQNNKECKIPTLEEVLILISPTD
                     LILNIELKTDKINYPNIEKDVLELILKYNMKNRVLISSFNSNSLKNFHKLDPSVKTGL
                     LCYLPINNVVNFAKFLGNSYLHPPLVLVNESLIELCHKNLLGVNVYTVNEEDDILHCL
                     KLNVDGIFTNYPDIASNLLHSKQYS"
     gene            9976..12165
                     /locus_tag="PC466_001820"
     CDS             9976..12165
                     /locus_tag="PC466_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid adenylation domain-containing
                     protein"
                     /protein_id="HDF2769207.1"
                     /translation="MYEVNLERAMNYWMDLLDDYTNIAKIPNDFFYKDCSDEVVDEVF
                     KMNIEKHERLIQYSKVNNISIDSIIETIYGLILQKYIYEDDVVFGKTMNIIPIRVRVR
                     QSEKFIDVVRKLKRQWSRSLEYGYYLLSDIENKNHLNTKLINTIFIAKSFDLSYDYDI
                     EKKGYDLSVIVYTKRALKIKIKYKPSIYKRETIRRILNQFDYIIEQIIEDNDILIEDL
                     EFVCKEEEKVLLEDFNNNQYEVPYDKSYVDLFREQVKVTPSNIAARDENRKLTYKELD
                     EVTDKLAGYLNHIGVESEDIVAVMLPRDINIIITAIGIMKSGGAFFPIDTSNPEERLN
                     YLLEDSNAKVVITTDELKSKVVNENTIVLDINDEEMFKLGYELTEKITSSNCAYTIST
                     SGSTGRPKTIAIEHKSLVNMCYYSVKSISATENDICGIYLSFSFDAVMKQLFPYLLVG
                     ASIDIMPEEAKFDEYTVNEYCEENDITILALPTAFARLFIQNCNNNSLRVVQTGGERL
                     KGYRKRNYELYNEYGPTEFTVVSTSFHVDREYGKIPIGKPIFNTYAYVLDKKNKLCPI
                     GAPGELCLSGIQISRGYLNKKGLTEQVFVENPYKTCEYNKLMYRTGDLVRWLDDGNLD
                     YIGRMDNQVKIDEFRIELYEIENIINNITEIKSVVCISRTNDDGDMYICAYYVIDEED
                     SGKINERTIREYLNEHLPPYMIPTIIMRIDKIPVTPIGKVNKKALPE"
     gene            12576..14504
                     /locus_tag="PC466_001821"
     CDS             12576..14504
                     /locus_tag="PC466_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide transporter, OPT family"
                     /protein_id="HDF2769208.1"
                     /translation="MNKKLPKGAYGEVSGKDYVPYITDKSRTGGNVAVLIIGIILAAI
                     FAASTTYSGMKAGLTVAAGIPGAIIGSAFVGAFARSKGILGKNLIQGMSSGGESVASG
                     FIFVLPAVILIGSQITFFEGLAVGVGGVLFGIGIAAIVHNYLIVEEHGKLMYPESMAI
                     SETLVASEAGGDSIKYMGIGFVISGFITVLTGSFLNVANNVMSLVGSKFYKWKFDIEV
                     NPLLLGIGFIVGLEVSLTMFAGSILSNFGIAPLIGYFTDMAKDGAMVWNNPAMPLNQM
                     DVGAISSSYVKYIGAGMMLCGGIIGAIKLIPTIIASIKETLKAKSSAGEGEEGSSIQM
                     ILLLGGVVIGFLAAFLISGNIVMAIIGAIISLLLSLLFVIVAGRLTGTIGTSNLPVSG
                     MTIASLVIVTLVFVIMGWTDLEANKSLLLFGSFIVVAIAIAGGYTQSQKVTYIIGGSK
                     NEMQRYFTIASIVGVIVVVGVILLLSDQLRATGDNVQFALPQANLMSTLTSGIMSGSL
                     PWVMIIVGVFMAIVLYALNLPIMTIAIGFYLPIATTSIILVGALIRLFVELVSKTEKE
                     KEVKVSNGISLSSGLVAGGSIIGLIGIILQVTGVVTPKVPSGFAATNSMAIALLVVLV
                     VLTTLPIVLSKVKNNEQE"
     gene            14491..14838
                     /locus_tag="PC466_001822"
     CDS             14491..14838
                     /locus_tag="PC466_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PqqD family protein"
                     /protein_id="HDF2769209.1"
                     /translation="MSKSNDVLDIVFKITDGLEYEVAENSVVTILEKQDHKIQKFFRK
                     LKARIPKYKKIELDEYSSFVFLQIDGQRTVREIGKNLEAKYGEESHPLYERLLVFLNH
                     IEVNCHYIERLDI"
     gene            complement(15080..16999)
                     /locus_tag="PC466_001823"
     CDS             complement(15080..16999)
                     /locus_tag="PC466_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_071223118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HDF2769210.1"
                     /translation="MNLMTLENISKSYSEKKLLENISLGINEGEKIGLIGVNGTGKST
                     LLKIIAGVEESETGNITKTNGIRIEYLPQNPTYNENSTVLEQVFNGTSEELKLLGEYQ
                     EILEKLNSNFTEELNKKLLSVHEKIDALNLWDLESEAKSVLTKLGINDFNQKIAELSG
                     GQRKRVSLASALITPCEFLILDEPTNHLDNDTIDWLEEYLNSRKGSLLMITHDRYFLD
                     RVTNRIIELDKGRLFSYDGNYSIFLEKKMERLSLEASIEDKRQNLIRTELAWVKRGAQ
                     ARSTKQKARLQRFDELMNRDSFKPDENLDISVASSRLGNKIIEIHNISKSFEENTVID
                     NLEYTLTRTDRIGIIGKNGMGKSTLINILNGEIEPDSGYISIGETVKIGCFSQDDSHM
                     NIDMRAIDYVKEASDYIETSDGTRITASQMCERFLFNGTMQYTLIGKLSGGERRRLHL
                     LKILMTAPNVLLLDEPTNDLDIETLKILEEYLDEFKGVVVTVSHDRYFLDRICNKIFA
                     YEGNGKIHIYTGNYSDYLIYREIQGIEFEESKRESVKKDDSTTLKKEKPKNDKKLKFS
                     YNEQREFENIDSDIEKLESKIATLDESTAKFSTDFTKLQEILDEKSKLEKELEYKYER
                     WEYLNNLADEIANNK"
     gene            complement(17025..17831)
                     /locus_tag="PC466_001824"
     CDS             complement(17025..17831)
                     /locus_tag="PC466_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HDF2769211.1"
                     /translation="MNLILGDNMSKKSKRRKINKLKLTIVITVLFLALLSIYEILFSN
                     PNKKGNIKSQETMQNKNNTTDDSKNNQSSTKKQEDNNIKPTFSYSSIPDNIKNKMIGK
                     SMPTDEPISFDSLSYLKLTYYGFDEKTHQGEMIVNSELAPEVVDIFKELYEKKYPIEK
                     IKLIDDYDAVDEKSMSDNNTSSFCYRTIAGTNVVSNHGKGRAIDINPLQNPQVSGNDV
                     TPKISTVYADRSSTKFGMIKKGDDCYNAFVSRGWSWGGYWKNPDYQHFEK"
     gene            complement(17890..19338)
                     /gene="ddlR"
                     /locus_tag="PC466_001825"
     CDS             complement(17890..19338)
                     /gene="ddlR"
                     /locus_tag="PC466_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator DdlR"
                     /protein_id="HDF2769212.1"
                     /translation="MIFSNLKLNDNEPIYIQLKNYISDMISKGLIPDNSKLPSTRELS
                     QLLQVSRNSVVLTYEELKSEGLIYSISGKGTFVKSKNKSSNTTWSLNWDCLENTYSKK
                     ANELDIIKSEIPWSSDLISFKSISPDGDLFDMEELKKSFLNRISLEGHKLLNYGYAQG
                     YKPLIDYLLEYMTNKGADISNKDILITNGFTEGFDIIMSSFTQEKDYIICENPTHNTA
                     IKIMKSHNLNILGVDINEDGLDFNMLEDNLVKYKNKIKFAYITPSYHNPTGIVMTPEN
                     RYKFYNLMKKYNIAIIEDGFNEELLYNSSHIFPICSLDNMNNGVVYIGSFSKILFPGM
                     RIGWIFADKKVINKLESVKRCRNIHVSFLDQGILFDYLSNGGFEKYIKKIRKFYGDKF
                     NFAYKCIKKYIKTEYILGDGGLHIFIKLKNIDTRVLLEKCYEKNVIFMPGDLFFTDNS
                     GFDTLRLGFSRLSFEDIEIGIKIIGETINEMF"
     gene            complement(19362..20261)
                     /locus_tag="PC466_001826"
     CDS             complement(19362..20261)
                     /locus_tag="PC466_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HDF2769213.1"
                     /translation="MKIAVIMGGISSEREVSLNSGKEIYNNLDKNKYEVVKVIIDDKK
                     DIFTKIPEDIDFAILALHGKFGEDGCIQSILETMDIPYSGCGPLCSGMCMDKNITKKM
                     LRDSNLPTAPWVLVKSVDEIDYDEIDNIGYPVFIKPNSGGSSVATFFIHSKDEVEEAV
                     RKGLEVDEFVMIEKYIPGGEYTSFILNGEVFPTISIKSDSGFFDYEAKYSVEKGAKEE
                     VVYLDEELQKRVNEISETCWKIFNCKAYVRVDMIISEGIPYVLELNTLPGMTQTSLIP
                     RSAAARGIKYSELLDKLIEYSLN"
     gene            20519..21775
                     /locus_tag="PC466_001827"
     CDS             20519..21775
                     /locus_tag="PC466_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011591286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HDF2769214.1"
                     /translation="MKAEIISVGTEILLGDIVNTNSQFLAKELASLGIEVYHQSTVGD
                     NKQRLLECFDESLKRSDFVITTGGLGPTGDDMTKETAAEYFGQKLELHKPSLEVLESF
                     FVKTGKKMAENNMKQVYFPKDAIVLKNNNGTAPGAILKKDGKFIIVLPGPPREMKAMF
                     NESVKPYLQQFTNEMLVSKTLRLYGIGESNLELEILDIINEQTNPTVALYAKELEVTI
                     RITAKAENEREAFKLIKPVEEKIKSRVGKYVYTEGDISISEGETALEDAVSKLLVEKN
                     LTIAVAESCTGGLVSSSLINYPGISSVFLEGCVTYSNDSKMKRLGVKRETLEEFGAVS
                     EQTAIEMAEGVAKGLKANIGISTTGVAGPGGGTKEKPVGLVYTAIYINGKTIVKKNIF
                     NGDRRKIRLRATRDLLNELRIQLEKL"
     gene            21845..22624
                     /locus_tag="PC466_001828"
     CDS             21845..22624
                     /locus_tag="PC466_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDF2769215.1"
                     /translation="MIKHIFCDLDGTLYENGTITKEDIVAIEEIEKKGVQFNVATGRI
                     FKQAHNIIKDSLDMNGYYVCENGSFIYDKDYNVIFKRTIDDNLVKKVIDRFESSDAQL
                     YFKYKGDVIVGSDTTAFRHYSSDFIVDPDFEKRSSFDNLIGNIGVCSENLEELSRIEL
                     YLKSEFSEVLEIYFSGTYTLNIVPKSVSKRGSIEHVIKTLNVSPDEVATIGDSPNDIC
                     MLEGFKYSFAMSKAREDVKQSANYVVDSVKSAIDVIMEINS"
     gene            complement(22728..23312)
                     /locus_tag="PC466_001829"
     CDS             complement(22728..23312)
                     /locus_tag="PC466_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc dependent phospholipase C family protein"
                     /protein_id="HDF2769216.1"
                     /translation="MLMNTHFIMAKSILDNIDENKTFFISEKNFIYGNIKPDAFSKYK
                     LKKHYLDESFNMIVSKINYLCSLNIDSLSKYFSVSRLSQELGVICHFLCDFFCVAHSE
                     RWEFKHSLNKHVTYERELGAFAKDVDLSKIKCGTINSSFEKFFTKLYSDYKKKTDYMN
                     DLKFSAYTCNSVINYILDSILSNTIKSYHIANCG"
     gene            complement(23512..24942)
                     /locus_tag="PC466_001830"
     CDS             complement(23512..24942)
                     /locus_tag="PC466_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2769217.1"
                     /translation="MNLDLEFYQKILEASHDEICVSDDKGIIIYCNKAFEENYGLKKE
                     DILGKNVSFLEDSGYSTKSPIPIVLKTKTKFSLEQDTQTGKKLIITATPIFDENGNLE
                     FTVENCRDITELNNIKNKLEDTKKQVKKYKSEVETLYRTALRIEDTVIMDGIVMRPII
                     NTVNHVSKTDVSVLLLGESGTGKSSLARYIHHNSNRSNGPFITINCATISPQLLESEL
                     FGYTSGAFTGASTKGKVGLVELANGGTLFLDEIGDIPQNLQAKFLQLIQDRTFTPVGS
                     LKNKKVDIRIISATNADLVSKVKEKKFREDLYYRLNVIEIKLPPLRERRDNLVEIIKY
                     YFNRYSSDFNLNKTISKEAMDAIANYRFPGNIRELQNIIQKILLTCTDNHITIDDLPN
                     ILTKNIHITNNGNKTHISQINKVIISDSKSTNYKNKNFDTLIKEYEKNIILDAYEKFG
                     SSYKVAKHLEISQSKANRLIRKYTNT"
     gene            25258..26202
                     /locus_tag="PC466_001831"
     CDS             25258..26202
                     /locus_tag="PC466_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HDF2769218.1"
                     /translation="MGEKSKGYVFIAIAGLLWATLGLFGKFLMGNGLTSEQVAFTRLF
                     FGFIVLGVYSSIRTPQILKISKKGIIYSVIIGIICQAMFNLCYFKAIDIAGVSIAAVL
                     LYTSPLFLAIFSKVCYKENITRSKLFSLILCFIGAIMAVTGGRLDFQGLNAFGLLLGV
                     LSAIAYALMPTISKNALKEFSSSTILVYSFLFGAIFMIPSSRPWEILNYAKDLDVLSC
                     MLMLGIVPAALAYIFYAAGISKGVELSVAGVVASVELVGSVIIGCTILGESFSLGKLF
                     GVMLMLISAVVALNLSYDEIRIFYKSNKLKQIEKTESI"
     gene            complement(26473..27408)
                     /locus_tag="PC466_001832"
     CDS             complement(26473..27408)
                     /locus_tag="PC466_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893027.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HDF2769219.1"
                     /translation="MDKFKYAFDDKRYHTWNYYLRNTFGEKVFKVSINAGFTCPNIDG
                     SLGYGGCTYCSKEGSGDFAGNPKDNLISQFYNIKEMMLKKWPHAKYIGYFQAYTNTYA
                     PLEVLKEKYETILELEDVIGLSISTRPDCLPDDVVEYLSELNKRTNLWVELGLQTIHD
                     STSKIINRGHDYKTFVEGVEKLKSKNIKVVVHIINGLPGEDYNMMMETAKAVGKMGVD
                     GIKIHLLHVIKDTPMEKMLQNGMLTLMEQDEYINLVCDQLEILPETMIIHRLTGDGKR
                     DELVGPIWSLKKWEILNQIDDTLKARNSYQGCKFV"
     gene            complement(27528..28121)
                     /locus_tag="PC466_001833"
     CDS             complement(27528..28121)
                     /locus_tag="PC466_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HDF2769220.1"
                     /translation="MNFCYNCSIDFGGDFMYTNFNIDFNNFNKKENATKFMLMGVLLI
                     ILGLLCLTFKTLGIKLISWTFGIALLFFAYLNLKNINELKRYATKEEIKPSINIQWVL
                     IIACILLFVFPQKIQSIFSLFLGFYLIFNQLVALVNSKNNPYSKFTTWNIVKILFGIC
                     LILSPLFLSRFIVSIMSFFIILFGLVLFFSGNTARKY"
     gene            28228..28656
                     /locus_tag="PC466_001834"
     CDS             28228..28656
                     /locus_tag="PC466_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HDF2769221.1"
                     /translation="MTKLWAIIFALLAGGSTALEAFINGELGKSTTALVATFISLTVG
                     AIFFLASIIVTGDLKCLVSINGFNYKLLLGGVFGGLIIYFTVKAIPNLGVSNTLILTL
                     VSQVLVGFFIDSVILGQETMHLYKYIGVILLILGTFFIVN"
     gene            28723..29391
                     /locus_tag="PC466_001835"
     CDS             28723..29391
                     /locus_tag="PC466_001835"
                     /EC_number="6.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphthine--ammonia ligase"
                     /protein_id="HDF2769222.1"
                     /translation="MKEVLKLADEKFVMSFSGGKDSILALNRMLKKGYKPVALLTTIS
                     EEHGKSWTHNLEYNMLKQVSSNIGLPLLVAECGVEGYEESFERALIKAKNMGATICAY
                     GDIDIESHRKWDTDRCEAVGMKVDLPLWQESREDLVYEFIDSGFCSVVTKVNLKHLGE
                     EFLGKKLTRELVEKIKNAGADPCGEHGEYHTFVVDGPIFKKPVEYEVKGTLIKDGYGY
                     LEIK"
     gene            complement(29509..30864)
                     /locus_tag="PC466_001836"
     CDS             complement(29509..30864)
                     /locus_tag="PC466_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF2769223.1"
                     /translation="MDTKISINENMSLGKRFFKYLAPSVVAMWVFSLYTMVDGIFVSK
                     GVGELALAAVNISMPFINFIFAVSLLFSTGASTIIAIYLGKKDIKSANEVFSFNLVSI
                     IILSIIILAITFFNLDRLALFLGATESTIGMVKDYLGIIIFFNGFFIVSYSLEVIIKT
                     DGFPILATVGVIISALTNIILDYLFVIEFGWGVKGAGIATVLSQVFSTIFFLIHFLRK
                     NSTLNFSKFRIDFKTLRKIVFIGFPDSTTELSCGIVVLLFNLSLTKYIGENALIYYSV
                     INYINTLVLMTMMGITQGMQPLTSFYYGAGNIDNVKKLLKMGIKATIIASVAVFAICM
                     AFSGPIVSLFIHPEETMLFNEGVRVFKIFSISFLLVGINVIISGFFVSVEKPSISTVI
                     SLGRGLVIVVLSLISMILIFGGQGIWMTTIVSEFICLILSLVFLKKNFSTLDSNLNKV
                     A"
     gene            complement(31406..31899)
                     /locus_tag="PC466_001837"
                     /pseudo
     CDS             complement(31406..31899)
                     /locus_tag="PC466_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429361.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
     gene            31995..32351
                     /locus_tag="PC466_001838"
     CDS             31995..32351
                     /locus_tag="PC466_001838"
                     /inference="COORDINATES: protein motif:HMM:NF012870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HDF2769224.1"
                     /translation="MVFETFDKVIKLHPNAKPVFHSDRGFQYTSKVFESKLLAQGMIQ
                     SMSRAGRCIDNAPMEGIWGILKVEMYYLRKFDTYEQLVKIIETYIYYYNNFRYQKRLN
                     SMSPLEFRKYLSTEIA"
     repeat_region   32882..33568
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=32948..32976
                     /rpt_unit_seq="gttttatattaactaagtggtatgtaaat"
     gene            complement(33960..35693)
                     /locus_tag="PC466_001839"
     CDS             complement(33960..35693)
                     /locus_tag="PC466_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HDF2769225.1"
                     /translation="MSILLKKAPKLAKHIITSFYINRDINEVLKYLCENVTWIGPGEQ
                     EFLTSFNEIKNYFYAGQDEIPSCDINNDVFETVSEDENRCMVLGRYTVRTKENAQMIL
                     EVNQRCTFEIIEDRGKLLVKHMHISNPYGEMQLDEYFPTKIGTQSYDYLQRLLKEKTE
                     VIEMITNNINGGLKGSNDDSTYSFFYVNEGLPKILGYTYDEFMEMSGGSAVGAVYPPD
                     LPKALEDCERCFAKGPTYSSEYRIRKKDGTLMWVLDSGMKSLNSDGIVKINSIITDIT
                     QLKNIESELKLERERYRIALQNITDIMFEYDIENDTLIKYQRVEIDKKIELENFETKN
                     YSKLLESGKIIHLDDIGKLLEVLHGNLRETIEIRQVNSLTKNEWRWIRVQCSVIYDSD
                     HNPIKTIGVLKDITEDKSKLESLINQAQRDPLTQLYNQRVSQNLIEEYLCSSDSKNND
                     ALLVIDIDDFKTVNDTFGHLEGNEVLVAVSKILLHNTHDKDIVARIGGDEFTIFIKSL
                     TKDLIIKITNDILNDASKIKVKDNHKITLSIGIAFTDDSTKLYKDLFSKADKALYLSK
                     ADGKNCYSTYE"
     gene            complement(35933..36778)
                     /locus_tag="PC466_001840"
     CDS             complement(35933..36778)
                     /locus_tag="PC466_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDF2769226.1"
                     /translation="MFKEIFLRTFPGFLIIRDSNYRIIFINDNLKNLIKSYMQDNPLG
                     MTNIEIAKKLPDNIAKFFTDSHNIQLDWEKNYPYDKISNWILEFKKDTTSYWNVLEYK
                     VDVDEKTYIITMANDITKLYEENKRNLHYSITDPLTGAYNRKYLNDRFDIFIGDYIVL
                     IDLDNFKMINDYEGHNVGDKILCDFVSLLNKELINSTSIIRLGGDEFIVIFSSDVDKN
                     YVYSQLEALRENFLKVFSKYKYLSFSYGVDTVKRNLKLTIVELDKKMYKNKEKNKKKF
                     DKNDY"
     gene            complement(36809..39043)
                     /locus_tag="PC466_001841"
     CDS             complement(36809..39043)
                     /locus_tag="PC466_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDF2769227.1"
                     /translation="MQNHNYIKMLNKKVEVLSKELDSRNFKLKTLNEIDFFSKIPNRE
                     FMYQYIDDCISKNIHIGIMLLNIDNFKLFNDIYGYLVGENLLITLTQNLLHFIPESKG
                     IVAYLKGEGFLIVLPNVSNKELNNMGATIIESSRELKIRLPNEKEIYSNVTFSIGSTI
                     WNGEPNMTTLILFNQVYSALKKAKSEGKNRYILFDFKDNSFYNKLENDKEFLSEISHV
                     LQTKQIEVFYQPLYNIKNNTIVGCEALARWRHPIKGLLTPDKFIPLFEQFGLITELDL
                     HLFEENCKNIRRWIDNNDVFVPICCNFSRLHFFNPNFPSMLKGITEKYSVSTSNFSIE
                     ITENILIENTNTIIQQLAELRSYGFSVSMDDFGSGYSSFGMLQNLPFDIIKIDRIFLS
                     HNLNDFKNTTILYSIINIARALGMLTVCEGVETEQHVEFIKSINCDIAQGYYYAKPME
                     CKEFEKLLSKENNSEKMFIKYSDIGKSLIEKIFDGFFIMQDMKKLRANVTEDIQWFDF
                     YNKTEITSFPKVIEHFEKHIKGKKFSILYKSITPHNTESDSLLISGEAVLSDEASEHQ
                     KYSNFYFSANCIISENKLLLAKLHLDLIKTAGYINEFESYSIPKMTNTHLDESNILSQ
                     FYSMLPVGIIRYDLFGDMIITYMNEEMFDIIGYTKEQFFGEMGGNLRAIVHPDDLDFV
                     YKKSLDMIDTNKIEPFLYRFIKRDGQIVTVMYTQCNLSAIDGRSIAQGMYVDVNKIKN
                     LTKI"
BASE COUNT        14211 a         4975 c         5708 g        14574 t
ORIGIN      
        1 tctgataata atccataaaa acatataact ttttagctat aattattatt gttattaatt
       61 gaaaagactt attagttact tgacatagtt tacactttta attatagtat aaattggaat
      121 atttagataa ttattattta atgtataagc taagttttta attaatatgg ctttatacat
      181 ttatatagaa aagaggtacg tatgagtagc acaatcaaat caaatcgaat aaaaggtata
      241 atgtttataa tagcatcagc gcttggcttt gcaatgatgt ctgcattcgt aaagctagct
      301 ggagatttac caagttttca aaaagtgttc tttagaaatc tggtatcagc tataatagct
      361 ttttggctta tcataaaaca taaaggaagt ctaactggta aaaaagaaaa tttaaaagta
      421 cttttatata ggtcaatatt tggaactcta ggagttatat ttaactacta tgcaattgac
      481 aagttgatgc tttcagatgc taatatgcta aataaaatga gtcccttcct tgtagtaata
      541 ttttgtgcaa ttgctctaaa agaaaaaata aatgtaaagc agataggagc tattataatt
      601 gcatttatag gagctttatt cataataaaa ccaacattta gtgtagaagt aattccatat
      661 cttgggggaa ttgcaggagc tgtatttgca gcaatggcat atacttgttt aagagttctt
      721 ggagatagag aagattacta tacaattgta tttttctttt cagttttttc attagttact
      781 gtagggccaa ttgcttttgc agtatatgaa ccaatgaccc ttatgcaact tatatatcta
      841 ttactaggtg gagtatttgc aagtctaggt caatttggaa taactttagc atataaatat
      901 gcacctgcta aggaaatctc tatatttgac tatagtaata taatcttttc agcaatttta
      961 agtatattct tattcaatgt ctatccagat atgttaagtg ttgttggata tttaatagta
     1021 ttttcggcag cattttatat gtttttatac aataagaagt tagataaatt agacaaagaa
     1081 aagaagaagt aaactagata aaagtgtttt tataatttgt attgaatatt taagtctttg
     1141 tattaaaatt aaagaaaatt taattaaaaa tgtttggtat attaacttat aacagcagtt
     1201 aaaattgaaa aattataact gctgtttctt ttattaaaaa tatccaaatg tctgtaaaaa
     1261 tagactataa tagagtagta taaataatat aaaggggata aattaaagta tggaaaaagt
     1321 gaaagttgct gtgattggag caggtaatag aggaacgtat gcatatgctc catatattta
     1381 tgaaaattct gatatatgtg aaatagttgc tgtagcagaa cctaaaaaag gaagacgaga
     1441 actatttaca caaaaatata acctagatag taaaaatgta tttgaaactt tagaagactt
     1501 ttttaaacat gacaagatgg cagatgcagt aataatagct acaaatgatg atagacatta
     1561 tgatgtagca aaactagctc ttgaaaaagg ttatcatgta ctattagaaa agccaatgtc
     1621 taatagttta gatggtttgg tacatataga tgacttgtgt gataagtata aagataagat
     1681 ttttatgatt tgccatgtac tgagatattc tccattttat aataaattaa aagaaattgt
     1741 agaaagcaaa aaattaggag agctagttag tatacaatat aatgaaaata taggatattg
     1801 gcattttgca catagcttta ctagagggaa ttggagaaat agcaatgaaa ccagcccttt
     1861 aattttagca aagagttgtc atgacatgga tattttgtta tatttagtag gaagtagatg
     1921 caaaaaaata tctgcatttg gaagcttaaa gcatcttaat aaccaaaatg ctagtggaga
     1981 gatggcacaa aattgtcttc agtgtttagt tgaaaaaaaa tgtccatatt cagcaaagag
     2041 aatttattta gaaaaagata gaagtataaa tagagctgtt cacataaatc caactgaaga
     2101 gaatctatta aatatactta agacaagtcc atatggaaga tgtgtttaca gatgtgataa
     2161 taatgttgta gacaatatgg taaatatatt acagtttgaa aatggagtga cggctacttt
     2221 taatttatgt gcatttacta aagaaaatgg aagaactata aagttaatgt ttagtcatgg
     2281 tgaagttggt ggggatttaa ataaaaatga gataagaatt aaaaaatttg gaaaaaacga
     2341 agaaatagtt atgaatccat caaatcaaca gaatatggta gaggaatatg atagaaatct
     2401 tatagctgaa tttattaaat tagtttcaaa taaagaacta gaaaagggta gagtagcagc
     2461 aaaagaagct atacaaagtc atgtaatggc atttgcagca gaatattcta gggtcagtga
     2521 tgaagtagtg tatatagaag aattttttga tagtgctaag caaatgacta aggagataga
     2581 agaaactata ttttaattaa taaaaattta ttaaataaaa taaagataga ttaaataata
     2641 gaaatacgaa aatatgtgtt ctattaagga atctatcttt tttattaagg ttttttctta
     2701 tccctatcaa aaaaatccat acattctgat aaaagataag aaagtaaagc gaataagatt
     2761 tctgtactta aaggaatcgt tactgaatcc ataaaggtat caattatgtt catagctaga
     2821 aaagttagta taaaatcaat tataaattcg caaagtttat atattgagta tggtaatttg
     2881 tttacatatc tgaatatatc taaaatagta gtgcatagaa aatcaattgg agtggttata
     2941 caaaaatata ttaaaaagaa aattaataca gctccaagag atttatattc aaatcctaag
     3001 aatgataaga agccaattcc tataaccgtg aaaatacaaa aagttatacc aaaaaaaaca
     3061 gcaaaaaata aaaatacaga aataaattcg cctaaaggaa tccttctttt attacttatc
     3121 ttaatcaact ccttaattta tgatatgaaa tttatataaa taataacatt cttaaaaatt
     3181 cataatagtc ctctgtttca aatagtactg tttgagaatc tatttttttc atatttggat
     3241 aaaaagaggc cttaaaagct ttataatgtt ctctaaattt tatttctatc ttaaatttat
     3301 ctggcaattt tattaagtgc ctagataaat ctccagataa agcttttttg acaccttttt
     3361 caattttttt tagtgcaagg tttggatgga ttgaaattga accatttcca attccttttg
     3421 acacaggaac agtgactata tttggattta gtttttttgc actctcacaa agcatttcat
     3481 ctccacttaa aaatgctaca ggaacattat aatatgcagc aatataagca tttatagtaa
     3541 attcagatgc tatttcatca tttattttaa aatagtcata atcaatatcc atagtatgag
     3601 aaagtggatt accattacaa gtagctccag agtgatagcc ggtgaatata catgcatcaa
     3661 agctttcatc aattccagcc atcataacta gtgggtcttt ggtccatcct ctaagtattt
     3721 tgacgttttc aggtaaaata tttggattaa tatttctacc actgtcatgt gcatctttaa
     3781 caagtatttc atgtacacca gattgagtag ctccatcaca tgctgctgtt atctctttac
     3841 tcatttgtgt tctatagtgt tgtgaaaatt cacattcaag ttttgtttca tcccaattta
     3901 caataccaca agtaccttct atatcagcac ttaaatacaa tttcataata tataccccct
     3961 tatgtttatt attgatgata ataacagata acagaaaata cataatcaat aaagggcata
     4021 aaaatattat gtcttactat taattattat taaatctgta actgaaaaat aactaaattg
     4081 gtattaaaaa atataacact atgtgtcatt tatttatata gttttttata tctgatgttt
     4141 atataaaatt gtaacatata agtggttaca tttactagtt taacatagtt aaaatagtta
     4201 ggtattattt ttaagttaaa ttgattatta taaaatcgta gaataaaaga aaaatttaat
     4261 ttattaaaat gcatgaaatg ttttttcctc aacataatgc taaattaaac tcaaaaagaa
     4321 ataatagaaa aatcttatgt agcttagaaa gaatgtgaat gatttaaggg aaaaatagaa
     4381 atttattata taatattagg ctgtattatg taatacagcc taatattata tgtatatgtg
     4441 acataaaatc ttggtaagtg taaataaaat aaatgtggaa aacaaattaa tgaaatcaag
     4501 aaaaaagtaa tttaaaattc aatttcatct tcccaattaa attctcctga tttttctaca
     4561 ctcttaggcc agtgactaca ccatttagga acggacggat tttcaaccct atcaacgctt
     4621 ggagtatatg gctttaagtc tataacagga ctattatcat tagcatcaat atatggtatt
     4681 tttattatac cattttcatg gtcgatattg ataatttgta cagcagtcaa tgctattgga
     4741 ttgggtctta taggtgacct tgttgcaaat attcctataa cgtttggtcc acttttataa
     4801 ggttttgggg tttctaaaat acttcttagt tcaggattat caaacccatc agcccaccaa
     4861 aatacattta aatgactgaa atcgtcgagt tcatttaatg caggtacata ctttttgtct
     4921 aatttaataa agacctcttc gccttgaata catattttac ctataggatt tattaatatt
     4981 tctttcataa tattacctcc aactatttaa tttatcattt gtaattttag ggtataacat
     5041 gacatcatgt gagggtcaat ataaaataat aaataaaaat attaatagtt agaatgataa
     5101 tacatttttt acatggagca tgacaccagt aataaggcaa tcttcgtcaa tatcaaaagt
     5161 agaggtatgc aaaggggaag taatgttttt ttcacgattt gcacaaccaa ggtggtaaaa
     5221 agctccttca cagtgtctta gaaaatacga aaagtcttca gccccaagag tgggcgagtc
     5281 tttaaggata atattttctt ctccaaacaa ttctacagca ttttgcttga cgtaatctac
     5341 tagatggttt gaattgataa gagctggata accttcctca atttcaacag aaatacttcc
     5401 tccaaatgtt ttacaagtaa aatcgcaaat ttctctaatt cgtttttttg aaaactctct
     5461 agtttcagga gtcaaggttc tcaaagtacc ccttataacc actttgtcac aaactatatt
     5521 ttccttgatt ccaccttcaa tctttcctag agaaataacc acagaatcag ttggatttgt
     5581 gtttcgacta acgattgtct gtagagctgt aataatatga gcagatataa caatagcatc
     5641 aataccttga tgtggataag ctccatgaca ttttgaacca tgtacagtta attgaagtgt
     5701 atcggtggaa gcatttagag tgttgtattt taattcaatt agatttttgt tgatattggg
     5761 atttacatgg agtccaaata tatattttac atttgggttt tcaagacatc catcttctat
     5821 cataagttga gccccaccaa tagtttcctc ggcaggttga aaaaagaatt ttacatttac
     5881 atttaagtaa ttctttaatt taaatagtat attacaagta cccagtaaaa tagcagtgtg
     5941 tgcatcatga ccacatgcat gcattttacc aatattaata gatttataag aataattaag
     6001 ttcttctgtt ataggtaagg catctatatc agctcttata gcaactgttt caaagtttgg
     6061 actcacgtta atgtatgcag ttatccctgt atgattctta tattcaatat aatttatacc
     6121 tatttcattt aagtatttaa taattttttt cttagtttga aattcttcta atccaagttc
     6181 tggagtctta tgtaaatctc ttcttatatt tataatccaa tcatttatct catgacaaag
     6241 agttcttata ttaagcataa aacacatcct aactatatta aaaatttatt tttcttcatt
     6301 aattatatta ttttatgtaa atcattatta tgtatcaagt acaaataaaa tatcttataa
     6361 ttatattaga gatatttagt atggagaaga atatatcatt ttataagaag aggtgtttaa
     6421 atgttaggaa taattgcgcc atctgggcca ttaagaaata caagtttgga ggaaataaag
     6481 tttaatttag aaagttatgg ttacgaagtt aagttttctg aaagttgtag tttaaattat
     6541 aaaggttatt tagctggtaa tgatgatatt agagcaaggg atatagaaga tatgttttta
     6601 gataaagatg tagatataat tatgtgctta agaggaggtt atggaacaac aagaatattg
     6661 gataaaataa attatgatat aataaagcaa aatccaaaac catttatagg tttttctgat
     6721 ataacaggtt taaatttagc tttttataaa aattgtggac ttttaccata tcatggaata
     6781 atggcagcaa atgtaggtaa atgggataaa tttacctata aatcattggt aaatgcttta
     6841 gaatttaaag atgacttata tttagaaaat ccaaaagaag aaaagattta tactgtatgt
     6901 gaaggtaaag cagagggaat aataatggga ggaaatttat ccttaataat tgccacaatg
     6961 ggaacaaaat atgaaataga tgcaaaagat aaaattttgt ttattgagga aattggagaa
     7021 cctcaatata aactggatag aatgttaaca caactatatt cttcaggaaa acttgaggaa
     7081 tgtaatggta taatttttgg agattttaag gattgtattg aagaaaatga tttgatggaa
     7141 ttactaatag aatttgcaaa taaggtcaat aaaccttcta tatataatct tcagtcagga
     7201 cattgtatcc caatgataac tattcctttg ggcagaatgt gcgaattaga tgctacagaa
     7261 aaaatcgtta aattaaaaaa atagtgtgta tataaatata atagaaatat ggtataatct
     7321 tatacaagta aaaatttagc taggaggatg aaaaatgtct gatgatagaa taatagactt
     7381 taacgaacta aagaacaaag ttaaagattc tgatgtagat aaatttgagc aatacatata
     7441 taacttatat ttttctgtta tggatggaaa gatgtccatg gctgagtttt caagaaaaat
     7501 attcgattat atgagagata acaacatatc tcaagaaaaa tttatgaaaa tacaaaagca
     7561 atttatggag agatatggta tggacactga agaagtagaa aaacaactta gaaactttgg
     7621 aatcgaccct tctacagcag gttttatgag taataatact tccagcaaag tatctacaga
     7681 agatttagag tcatttaaga agagtgcagg attttatgag aaatatggag aaaaaatcca
     7741 accaaagagt tgtataacaa catttataaa aaatgactta aatgatatta atgtaataat
     7801 cgaccaagaa aagataatgc tttgtagtga tagaaaaata aatcttatgg attcagaact
     7861 aaatgagttt ttattagaat ataagaatat gtttaataaa aaaataaagg tagtaatgtg
     7921 cgaaactacg aataagtatg attattaaaa aatgaattta aatactgaag tagtatcaat
     7981 taattgtact acttaaaaat aaaaatcgca atttattatt ccttataaat ttgtataagg
     8041 aatatctaaa ctgcgatttt ttatattgtg aagattagtc ataatagata gtgttttaaa
     8101 ttgtaatctt ctcactaaaa ctgtgttttt ctattagaaa ttttattaaa aataaatatc
     8161 tgataattgt attatatggg atgtaaagta ttagaggctt aacgaatctc ttttaataca
     8221 ttaactccat tttgaatcat actgttgaaa aatactaagt ttaaaatctc agcagggtga
     8281 atgttaggaa tatcataagt atctactaaa ttcataggta caactatatt tttttcaata
     8341 ttatgttgat taaaatatga ttttagagtt attgcaaatt gatatatgca tatatctgtg
     8401 caatcgccaa ctataattat attatctata ttatcaaaat ccaaattttc taatgcaaaa
     8461 aatccattag tagaattttt aggaagaatt tgtaggtttt ctatcgactt aagttcatca
     8521 accaattcac tttctacatc attttccaaa cagtgaacag gataactcaa aagttctatt
     8581 gatttaggag tatgagaatc agtaaatgct attactctat ttaatttgtt tgatattttt
     8641 tttgtaaaca tttcaattgg ttttattaaa gactctactc taggagagta taatgcacct
     8701 tgtcttgcaa agccattatt aacatcaatt ataaataaag cagttttact caaatcataa
     8761 ttttctattt tttctattgg tagattatct aaattactct ttaaagcttc aagttcattt
     8821 aataagttat ccatagttat acctccaaga taaatttaat aaaattgtac atattaatta
     8881 tataaaagtc aaggagtaca aactattgta taattagctg tattgttttg agtgtaaaag
     8941 atttgaagca atatctggat agttagtaaa aataccatct acattgagtt ttagacagtg
     9001 tagtatatca tcctcttcat ttacagtata tacattgaca ccaagtagat ttttgtgaca
     9061 aagttcaatt agagattcat ttactaaaac tagaggtgga tgaaggtaac tattacccag
     9121 aaatttagca aaattgacta cattgtttat aggtaaataa cacaataatc ctgtttttac
     9181 actagggtct aatttatgaa agttttttaa gctattgctg ttgaaactag atataagaac
     9241 tctatttttc atattatact ttaaaataag ctctaaaacg tctttttcta tattgggata
     9301 gtttattttg tcagttttta gttctatatt taaaataagg tctgtaggtg aaattagaat
     9361 taatacttct tctaaagttg gaattttaca ttctttattg ttttgatatc cttcaaaaga
     9421 tgagtttaga gtttttaatt ttcttaaagt aaagtctttt acaaaaccat gtccattaaa
     9481 agttctatca accttttcat catgaataac tacaattttt ccatccttag ttctgtggac
     9541 atcaagttct attccatata tatccatata caaacatttt ttaaaagcta gaatagtatt
     9601 ttctggatac tttccactaa accccctatg agcataaata ttcatttata tggttccctc
     9661 ctataagtat aacttatctt ataaaaattt aattaatata atatatcata ttccaaaagg
     9721 tattgttata tattagttaa ataactattt gtaatttata tattatataa atgtagaaaa
     9781 ataaaatcat atatgtgtta taatatattt taaacattgt aaatattacg aatttagtag
     9841 tcataataag tgtaatttta tgcaagctca tgtttttaga gcttgcatat gtattattaa
     9901 tatatttata tattgtgaaa ataaaattcc aaaagaattt tttctataga cttagtagta
     9961 agggggaatt ttgatatgta tgaagttaat ttagaacgag ctatgaatta ttggatggat
    10021 ttgttagatg attatacgaa tatagcaaaa attccaaatg atttttttta taaagattgt
    10081 tctgatgaag tagtagatga ggtttttaag atgaatattg agaaacatga aaggttaatt
    10141 caatattcta aagtgaacaa tattagcata gactctatca tagaaactat atatggcctt
    10201 atacttcaaa agtatatata tgaagatgat gtagtttttg gtaaaacaat gaatataatt
    10261 ccaataagag taagagttag acaaagtgaa aaatttatag atgttgtaag gaagctaaaa
    10321 aggcagtgga gcaggtcttt agagtatgga tactatttgt tatcagatat agagaataaa
    10381 aatcatctaa atactaagct tataaacaca atatttatag ctaaaagttt tgatttatca
    10441 tatgattatg acatagaaaa aaaaggatat gatttatctg taatagtata tactaagagg
    10501 gcacttaaaa taaaaataaa gtataaacca tctatatata aaagagaaac tattagaaga
    10561 attttaaatc aatttgatta tataatagag caaataatag aagataatga tattttaata
    10621 gaagatttag aatttgtatg taaggaagaa gaaaaagtat tattggaaga ctttaataat
    10681 aatcaatatg aagtacccta tgataaaagt tatgttgatt tatttaggga gcaagttaag
    10741 gtaacaccta gtaatatagc tgctagggat gaaaatagaa agttaacata taaagaattg
    10801 gatgaggtaa ctgataaact tgcaggttat ttaaatcata taggagtgga aagtgaagac
    10861 atagtagctg taatgttacc aagagatatt aacataatta ttacagcaat agggattatg
    10921 aaatcagggg gagcattttt tccaatagac acgagtaatc cagaagaaag attgaattac
    10981 cttcttgaag atagtaatgc aaaagtagtg ataactacag atgaactcaa aagtaaggtt
    11041 gtaaatgaga ataccatagt actcgatata aatgatgaag aaatgtttaa gcttggatat
    11101 gaattaactg aaaaaataac atcatcaaat tgtgcatata cgatatctac ttcagggtca
    11161 actggtaggc caaagaccat agctatagaa cataagagtt tagtaaatat gtgttattat
    11221 agcgtaaaat ctataagcgc tacagaaaat gatatatgtg gtatatactt aagtttcagt
    11281 tttgatgctg taatgaaaca actattccct tatttgcttg taggtgcatc aatagatatt
    11341 atgcctgaag aagctaaatt tgatgaatat acagtaaatg aatactgtga ggaaaatgac
    11401 ataactatac tagcattgcc aacagcattt gcaaggttat ttatacaaaa ttgcaataat
    11461 aattcactta gagttgtaca gactggagga gaaagattaa aaggatatag aaagcgtaat
    11521 tatgaactat ataatgagta tggaccaacc gaatttactg ttgtatcgac ttcttttcat
    11581 gtggacagag aatatggaaa aataccaata ggaaaaccta tatttaatac ttatgcatat
    11641 gtattagata aaaagaacaa actatgtcca attggagcac caggagagct atgtctatca
    11701 ggcattcaaa tatcaagagg atatttaaat aaaaaagggc taacagagca agtatttgta
    11761 gagaatcctt acaaaacttg tgaatataat aagttaatgt atagaactgg tgatttagta
    11821 agatggttag atgatggaaa tttagattat attggaagga tggacaatca agtaaaaatt
    11881 gatgagttta ggatagagct atatgagatt gaaaatataa taaataatat tacagaaatt
    11941 aaaagtgttg tttgtatatc gagaacaaat gatgacgggg atatgtatat atgtgcatat
    12001 tatgtaattg atgaggaaga tagtggtaag ataaatgaaa gaaccattag agaatattta
    12061 aatgagcatc tacctccata tatgattcca acaataataa tgaggataga taaaatacca
    12121 gttacaccaa taggaaaagt aaataaaaaa gcactaccag agtgattttt tattatgaca
    12181 ggtgttgtaa agtgattcca tacatttctt tatgacacct atttttctga ggaaatcaat
    12241 tgatgtaaaa aaaagaattt tctgtatata tttactatgg tgaaaattta tttataagaa
    12301 tgattattgt attttttata cttttccgtg ttttaaagca ttttttttac aaaattaatt
    12361 ttacattaaa aatttttttt attttatatc ttaatagttt ttagtagaat tgaaaaataa
    12421 aaagaaaatt agcataaaaa tatctaaaag tagaaattaa taatataggg ttaaatttta
    12481 gtagttttga ctcgctattt gtaaaataat aaaaagttaa gttttatatg tatatatgtt
    12541 ataatatata caaattgaaa aggggtgaaa attttatgaa caaaaaatta cctaagggtg
    12601 cttatggtga ggttagtgga aaagattacg ttccatatat cacagataag tccagaaccg
    12661 gtggaaatgt agctgtactg attatcggta ttattttagc tgccattttt gccgcatcta
    12721 caacttactc tggaatgaaa gccggtctta cagttgctgc aggtattcca ggagctataa
    12781 taggttctgc ttttgttgga gcatttgctc gttcaaaggg tattcttggt aaaaacttaa
    12841 tccaagggat gtcaagtggt ggagaatctg ttgcaagtgg atttattttc gtattaccag
    12901 cagttatatt aattggaagc caaattacat tctttgaagg cctagctgtt ggagttggtg
    12961 gagttttatt tggtatagga attgctgcta tagttcacaa ctatctaata gttgaagaac
    13021 atggtaaact tatgtatcca gaatcaatgg ctatatctga gacacttgtt gcttcagagg
    13081 ctggtggaga ttcaattaag tacatgggaa ttggatttgt aataagtgga tttattactg
    13141 tattaactgg ttcattctta aatgtagcaa acaatgtaat gagtcttgta ggaagcaaat
    13201 tctacaaatg gaaatttgat attgaagtaa atcctctact tttaggaatt ggatttatag
    13261 tagggcttga agtttcttta acaatgtttg caggaagtat tttatcaaac tttggtatag
    13321 cacctttaat aggatacttt acagatatgg ctaaagatgg agctatggta tggaataatc
    13381 ctgcaatgcc tcttaaccaa atggatgtcg gagcaatatc tagtagttat gtaaaatata
    13441 taggtgctgg tatgatgctt tgtggaggta ttattggtgc aataaaactt ataccaacta
    13501 taatcgcttc tataaaagaa acacttaaag ctaaatcaag tgctggagaa ggagaagaag
    13561 gttcatctat acaaatgata cttttattag gtggagtagt tattggattt ttagcagcat
    13621 tcttaatttc tggtaacatt gttatggcaa ttattggagc tatcatatct cttttattat
    13681 ctttattatt tgtcatagta gctggtcgtt taacaggaac aattggaaca tcaaatcttc
    13741 cagtttctgg tatgactata gcttctctag ttattgtaac attagtgttt gttataatgg
    13801 gatggactga tttagaagct aataaatcat tacttttatt tggttcattt atagttgttg
    13861 ctattgctat agctggaggt tatactcaat ctcaaaaagt aacttatatt attggtggta
    13921 gcaaaaacga aatgcaacgt tactttacaa ttgcaagtat agttggtgtt atagttgttg
    13981 taggagtaat tttattactt tctgaccaac ttagagcaac tggtgataat gtacaatttg
    14041 cattaccaca agcaaactta atgtcaacat taacttctgg tattatgtca ggtagtttac
    14101 cttgggttat gattattgtt ggagtattta tggcaatagt tctatatgca ttaaatttac
    14161 caataatgac tatagctata ggattctatt taccaattgc aacaacttct ataatattag
    14221 ttggagcatt aattcgttta tttgttgaat tagtatctaa aactgaaaaa gaaaaagaag
    14281 ttaaagtttc taatggtata agtttatctt ctggtcttgt tgctggtggt tctatcattg
    14341 gtttaatagg tataatatta caagtaactg gagttgtaac tccaaaggta ccaagtggat
    14401 ttgctgcaac aaattcaatg gcaattgctt tattagtagt tttagttgtg cttacaacat
    14461 tacctattgt tttatctaaa gtaaaaaata atgagcaaga gtaatgatgt tttagatatt
    14521 gtatttaaaa ttactgatgg acttgaatat gaagtagctg aaaatagtgt tgttactata
    14581 cttgaaaaac aggaccataa aattcaaaag ttttttagaa agttaaaagc tagaatacct
    14641 aaatacaaaa aaatagaact agatgaatat tccagttttg tttttttaca aattgatggt
    14701 caaaggactg ttagagaaat aggcaagaac ctagaagcta aatatggaga agaatctcat
    14761 ccactttatg aaaggttgtt agtattttta aatcatattg aagttaattg tcactatatt
    14821 gaaagactgg atatatagat ataataagaa ttattataga tatattaaag catataaatt
    14881 agaaggtaat tatgaaagag gctgtctcaa aatagagata agcctctttt gtattgttga
    14941 aatgatgaaa acatatttga tttctcataa aaaagagtgt ctcataaaac taaaaagttc
    15001 attttgagac actaccttta aaatatttat aaagtataga tttaaagcaa aacttattaa
    15061 acttaagatt attttaatat cacttattat tagctatttc atcagctaga ttatttaaat
    15121 attcccatct ttcatatttg tattcaagtt ccttttctag tttagatttc tcatctaaaa
    15181 tttcttgaag tttagtaaaa tcagttgaaa attttgcagt actttcatca agtgttgcaa
    15241 ttttagattc gagtttttct atatcagagt caatattttc aaactccctt tgttcattat
    15301 atgagaactt aagcttttta tcatttttag gtttttcttt ttttagggta gtagagtcat
    15361 cttttttaac tgattccctt ttagattctt caaattcaat tccttgaatc tctctataaa
    15421 taagataatc actgtaatta cctgtataga tatgaatttt tccattacct tcatatgcaa
    15481 atattttatt acaaattcta tctaagaaat atctatcatg tgatactgta actactacac
    15541 ctttaaattc gtctaggtat tcttctaata ttttaagcgt ttcaatatct aaatcatttg
    15601 taggttcatc taaaagaagc acattaggag ctgtcataag gattttaaga agatgtagtc
    15661 ttcttctttc accaccagat aatttaccta tcaaagtata ttgcatagta ccattaaaaa
    15721 ggaatctttc acacatttga gaagctgtaa tcctagtacc atctgaagtt tctatatagt
    15781 cactagcttc ttttacatag tctatagccc tcatatcaat attcatatga gagtcgtctt
    15841 gagaaaaaca acctatttta actgtttctc caattgaaat atatccacta tcaggctcta
    15901 tttctccatt aagtatattt ataagggtag atttacccat accatttttg cctattatac
    15961 caattctatc tgtacgagtt aaagtgtatt ctaaattatc tataacagta ttttcttcaa
    16021 atgatttaga tatattgtgt atttctatta ttttatttcc aagtctactt gatgcaacag
    16081 atatatcgag attttcatca ggtttaaaag aatctctatt cataagttca tcaaatcttt
    16141 gtaaacgagc tttttgttta gtgctacgag cctgagctcc tcgttttacc cacgcaagct
    16201 ctgttcttat taaattttgt cttttatctt caatacttgc ttctagcgaa agtctttcca
    16261 ttttcttttc caaaaatatt gaataattcc catcataact gaataatcta cccttgtcca
    16321 gttcaataat tctatttgta acacggtcta aaaagtatct atcatgagtt atcataagca
    16381 atgagccttt tcttgaatta agatattcct caagccaatc tatagtatca ttgtctagat
    16441 ggtttgtagg ctcatctagt atcaaaaact cacaaggtgt aataagggct gatgccagag
    16501 agactctctt tctttgccca ccagaaagtt ctgctatttt ttgattaaag tcatttatac
    16561 caagctttgt aagtactgac ttagcttcac tttctaaatc ccaaagattt aaggcatcta
    16621 ttttttcgtg tactgataat aattttttat ttaattcctc tgtaaagttt gaattaagtt
    16681 tttctaggat ttcttgatat tcaccaagta gctttaattc ttcagaagtt ccattaaata
    16741 cttgttcaag tacagttgaa ttttcattgt aagttggatt ttgaggtaga tattctatcc
    16801 taataccatt agtttttgtt atattaccag tctcactttc ttcaactcct gcaataattt
    16861 tgagtaaggt agatttacca gtaccattta caccaataag tcctattttt tccccctcat
    16921 ttattccaag agatatattt tctagtaatt ttttttcaga atagctttta cttatatttt
    16981 ccaatgtcat taaattcata taattcacct ttatttctaa tctattattt ttcaaaatgt
    17041 tgataatctg ggtttttcca atagccaccc caactccaac ctctgcttac aaaagcatta
    17101 taacaatcat cacctttttt tatcattcca aattttgtgc tagacctatc agcataaact
    17161 gtacttattt taggtgtaac atcatttcca gaaacttgag gattctgtaa tgggtttata
    17221 tctatagcac gtcctttacc atgatttgaa actacatttg taccagctat agttctataa
    17281 caaaatgatg aggtattatt atcagacata gatttttcat ctacagcatc atagtcatct
    17341 attaatttaa ttttttcaat tggatatttt ttttcgtata attccttaaa aatatccact
    17401 acttctggag ctagttcact gtttactatc atttctcctt gatgagtttt ttcatcaaat
    17461 ccataatatg taagttttaa ataagataga ctatcaaagc ttataggttc atcagtaggc
    17521 atagatttac caatcatttt attttttata ttatctggta ttgaagaata tgaaaaagta
    17581 ggcttgatat tattatcttc ctgctttttg gtagagcttt gattattttt agaatcatct
    17641 gttgtattat ttttattctg catagtttct tgactcttta tattaccttt tttgttggga
    17701 ttagagaaca gtatctcata tatagataat aaagcaagaa ataatacagt tattacaatc
    17761 gttaatttta atttattaat ttttcttcgt tttgactttt tactcatatt atcccccagt
    17821 attagattca tataaactat atatattata cctcataaaa ataaactagg ctaacaatat
    17881 ttagttaacc tagaacattt catttatagt ttctccaatt atttttattc caatttcaat
    17941 gtcttcaaaa gacaacctag aaaatccgag tcttaaagta tcaaaaccag agttatctgt
    18001 aaaaaataaa tctccaggca taaatataac atttttttca taacattttt ctaataaaac
    18061 tctagtatct atatttttta gttttataaa tatatgcaaa cctccatcac ccaagatata
    18121 ttctgttttt atatattttt ttatacattt atatgcaaag ttaaatttgt ccccatagaa
    18181 tttacgtatt tttttaatgt atttttcaaa acctccatta cttaaataat caaataaaat
    18241 tccttggtct aaaaaggata catgtatgtt tctgcacctt tttacacttt ctagtttatt
    18301 gattactttt ttatctgcaa atatccatcc aattctcatt ccaggaaata aaatttttga
    18361 aaaactacca atatatacga ccccattatt catattatct agggaacaga taggaaatat
    18421 atgagaacta ttgtagagta attcttcatt aaatccatct tctataattg ctatattgta
    18481 ttttttcata agattataga atttgtacct attttcagga gtcattacaa ttcctgtagg
    18541 attgtgataa gagggtgtaa tgtatgcaaa ctttatttta tttttatact taactaaatt
    18601 gtcttctagc atattgaagt ccaaaccatc ttcatttata tctacaccta agatattgag
    18661 gttatgagat ttcataattt ttatagcagt attatgagta ggattttcac atattatgta
    18721 gtctttttct tgggtaaaag atgacataat aatatcaaag ccttctgtga atccatttgt
    18781 tattagtata tctttattac ttatatcagc acccttgttt gtcatatatt ctagtaaata
    18841 gtcaataagg ggcttataac cttgtgcata tccatagttg agtaatttat gtccttctag
    18901 tgaaattcta tttaaaaagg atttttttaa ttcttccatg tcgaataaat ctccatctgg
    18961 agaaatactt ttaaaggaaa tcaggtcaga gctccaagga atttcacttt ttataatgtc
    19021 caattcattg gcttttttag agtatgtatt ctctaaacaa tcccagttta atgaccatgt
    19081 agtatttgaa gacttattct ttgatttaac aaatgtacct tttcctgaaa tagagtagat
    19141 taatccttct gattttaatt cttcataagt taaaactaca gaatttcggc taacttgtaa
    19201 aagctgacta agctcccttg tagaagggag cttactattg tctggaatta gtccttttga
    19261 tatcatatca cttatataat ttttaagttg tatataaatt ggttcattat catttagttt
    19321 tagatttgaa aatatcaaat taccacctca aattatttca tctaatttaa agagtattct
    19381 ataagtttat ctaatagttc actgtactta atacctctag cagcagcact tctaggaatt
    19441 aaactagttt gagtcattcc aggaagagta tttagttcaa gaacatatgg aataccttca
    19501 cttataatca tatcaactct tacatatgct ttgcaattaa aaattttcca acaagtctca
    19561 gaaatttcgt ttactctttt ttgaagttct tcatctaagt aaacaacttc ttcctttgca
    19621 cctttttcaa ctgagtattt agcttcataa tcaaagaatc ctgaatcaga ttttatagat
    19681 attgtaggga acacttctcc atttaatatg aatgaagtat attctccacc tggtatatat
    19741 ttttcaatca ttacaaattc gtcaacttcc agaccttttc taactgcttc ttcaacttca
    19801 tccttagaat gaataaagaa tgtggctaca cttgaacctc ctgagtttgg ttttataaat
    19861 actggataac ctatattatc tatttcatca tagtcgattt catcaactga ttttactaaa
    19921 acccatggag cagtaggtag gtttgaatct ctaagcattt ttttagttat atttttatcc
    19981 atacacatcc cactgcaaag aggtccacat ccagagtatg gtatatccat agtctcaagt
    20041 attgattgaa tacatccatc ttcaccaaat tttccatgta aagcaagtat tgcaaaatct
    20101 atatcttctg gtatctttgt aaatatatct tttttatcat ctattattac ttttacaact
    20161 tcatatttat ttttatcaag gttattatat atctcttttc ctgaatttaa agaaacttct
    20221 ctctctgatg atattccacc cattataact gctattttca tattatacac tcctatttta
    20281 atttttatta ttttaaagta aactttttat ttacatactt aattatatga attaacagtt
    20341 gaggatgaaa gtaccactat atacgaagtt tatattatgt gtggttttag aataataatc
    20401 tagtttaaag atatgtttaa atgatttttt aactttattt atgttattat ttttgctaaa
    20461 attattgtta tgaacttaag actagtctta atggctataa atcaaggagt gataaatttt
    20521 gaaagctgaa ataataagtg taggaacaga aatattattg ggagatatag taaatacaaa
    20581 ttctcaattt ttagctaaag aacttgcatc attgggaata gaagtatacc atcagagtac
    20641 tgttggagat aacaaacaaa gacttttaga atgttttgat gaaagcttaa agagaagtga
    20701 ttttgtaatt actacaggtg gtcttgggcc aactggtgat gatatgacaa aagaaactgc
    20761 tgcagaatac tttggtcaga aattagaact acataaacct tcactagagg ttttggaatc
    20821 tttctttgtt aaaacaggaa aaaaaatggc cgaaaataat atgaaacaag tgtactttcc
    20881 aaaagatgct atagtactaa aaaataataa tggtacagct ccaggggcaa ttttaaaaaa
    20941 agatggtaaa tttataatag tattgcctgg acctccaaga gaaatgaaag ctatgtttaa
    21001 tgagagtgtc aaaccttact tacaacaatt cacaaatgaa atgctagtat ctaagacttt
    21061 aagattatat ggaataggtg agtcaaatct agaattagaa attctcgata taattaatga
    21121 gcagactaat ccaacagttg ctttatatgc aaaagaatta gaagttacaa taagaataac
    21181 tgcaaaggct gaaaatgaaa gagaagcttt taaattaata aaaccagtag aagaaaaaat
    21241 aaaaagtaga gttggtaaat atgtatatac tgaaggagat atttccatat ctgaagggga
    21301 gactgcttta gaagatgctg tttctaagtt acttgtagaa aaaaatctaa caatagcagt
    21361 ggctgaatct tgtactggag gtttggtttc ttcatctctt ataaactatc caggaatatc
    21421 ttctgtattt cttgaaggat gtgtaacata ttctaatgat tctaaaatga aaagattagg
    21481 agtaaaaaga gaaactttgg aagagtttgg agcagtaagt gagcaaacag ctatagaaat
    21541 ggctgagggc gttgctaaag gacttaaagc taatataggt atatccacaa ctggagtagc
    21601 tggacctggt ggaggaacca aagagaagcc tgtgggacta gtttatactg caatatatat
    21661 aaatggaaaa acaatagtaa agaaaaatat atttaatggg gatagaagaa agataagatt
    21721 aagagctact agagatttac ttaatgaatt gagaatacaa ttagaaaagc tttaagttgt
    21781 tatgatattg gatatatttg aagtgttact ataatataaa attgtttttg gaggctttta
    21841 atttatgata aaacatatat tttgtgattt agatggaact ctatatgaaa atggaaccat
    21901 aacaaaagaa gatatagtag caattgaaga aatagaaaaa aagggagtac agtttaatgt
    21961 tgctacaggt agaattttta aacaagcaca taatattatc aaagatagtt tagatatgaa
    22021 tggatattat gtatgtgaaa atggttcatt tatatatgat aaagattata atgtaatttt
    22081 taaaagaacg atagatgata atttagtaaa aaaagtcatt gatagatttg aatcaagtga
    22141 tgcacaactt tattttaaat ataagggtga tgtaattgtg ggtagtgata ccactgcttt
    22201 tagacattat tctagtgact ttatagttga cccagatttt gaaaaaagaa gtagttttga
    22261 taatcttata ggaaatatag gcgtatgttc tgaaaatttg gaagagttat ccagaataga
    22321 actttatcta aaaagtgagt ttagtgaagt attagaaata tatttttctg gaacatatac
    22381 tttaaatata gttcctaaaa gtgtgtcaaa aagaggaagt atagagcatg taataaaaac
    22441 gttaaatgta agtccagatg aagttgctac tattggggat tctccaaatg atatttgcat
    22501 gttagaagga tttaaatata gttttgcaat gtctaaggca agggaagatg taaagcaaag
    22561 tgcaaattat gtagtagata gtgtaaaaag tgccatagat gttataatgg agataaatag
    22621 ttagtataaa aaatgactgt cctagagaag tataaaatta tattctatag agcagtcatt
    22681 ttaattatat tcaattataa gtttatataa atttaaaaat tcttaagtta accgcaattt
    22741 gctatatgat atgattttat tgtattagat aaaatagagt caagtatata atttatgaca
    22801 ctattacaag tataagctga aaattttaaa tcattcatat aatcagtttt ctttttgtaa
    22861 tcactataaa gtttagtaaa aaacttctca aaactactat ttatagtacc acatttaatt
    22921 ttagataaat caacatcttt tgcaaatgct ccaagttctc tttcataagt aacatgttta
    22981 tttaagctat gcttaaattc ccaacgttca ctgtgagcta cacagaaaaa atcacataaa
    23041 aaatgacata tgactcctag ttcctgacta agtctactta ctgaaaagta tttagaaaga
    23101 ctatctatat taagactgca tagatagttt attttagaaa caatcatatt aaatgactca
    23161 tctaaataat gtttttttaa tttatattta gaaaaagcat caggctttat attgccatat
    23221 ataaaatttt tttcgcttat aaagaatgtt ttattttcat ctatattatc aagtattgat
    23281 tttgccataa taaaatgggt attcattaac atatttacac ctcgtatagt ttattagact
    23341 tattaaatat attattatga tatgatattt atgataaaag tttaatggta aatatatgaa
    23401 actaagtcaa cagtatttat ttaaataatt tcaaccatat tcataataac agtaaatggc
    23461 caaatttaca atatgtaaat agtgttaagt ttttatttat caaatttaaa attaagtatt
    23521 agtatacttt ctaattaacc tattggcttt agactgtgag atttcaaggt gtttggctac
    23581 tttataagaa ctaccaaatt tttcataagc atccaaaatt atattttttt catactcttt
    23641 aattaaggtg tcaaaatttt tatttttata attagtagat tttgagtcag atataataac
    23701 cttattaatt tgggatatat gtgttttatt tccattattg gtaatatgta tattttttgt
    23761 aagaatgttt ggtaagtcat ctattgttat atgattatct gtacaagtaa gcaagatttt
    23821 ttgaattata ttttgtaatt ctcttatatt gcctgggaat ctataatttg caatagcatc
    23881 catagcttct ttagaaatag ttttatttag gttgaagtca cttgagtacc tattaaaata
    23941 atattttata atttccacta gattatccct tctttctcta agaggaggca attttatttc
    24001 tataacattt aatctatagt ataaatcttc tctaaacttt ttttctttta cttttgaaac
    24061 taaatcagca tttgtagcag atataattct tatatcaacc tttttatttt ttaagctccc
    24121 aactggagta aaagttctat cctgtattaa ttgcaaaaat tttgcctgta gattttgtgg
    24181 tatatctcct atttcatcta aaaaaagagt tcctccatta gctaattcta cgagcccaac
    24241 tttaccttta gtacttgcac ctgtaaaagc acctgaagta tatccaaaaa gttcagattc
    24301 aagaagttgt ggagatatag ttgcacaatt tattgttata aatgggccat tagatctatt
    24361 gctgttgtgg tgtatatatc tagcaagtga gctttttcct gttccagatt cacccaataa
    24421 aagtacactt acatccgttt tagaaacatg atttactgtg tttatgattg gtctcatcac
    24481 tattccgtcc ataattacag tatcttcaat tctaagtgca gttctgtata gtgtttctac
    24541 ctcagattta tattttttta cttgcttttt tgtgtcttca agtttatttt ttatattatt
    24601 aagttcagtt atatctctac aattttcaac agtaaattct aagtttccat tttcatcaaa
    24661 tataggggta gcagttatga taagcttttt ccctgtttga gtatcttgtt ccagtgaaaa
    24721 tttagtcttt gtttttaata caattggtat ggggcttttt gttgaatatc cagagtcttc
    24781 taaaaaagaa acattttttc ctaaaatatc ttcttttttt agaccataat tttcttcaaa
    24841 tgctttatta caatatatta ttattccttt atcatcagaa acacatattt catcatggga
    24901 agcttctaat attttttgat aaaattccaa atctaaattc atttttatat tttcctccta
    24961 aatttttaat gatatattaa aataggttta attgattaat atacttaaaa tttgatattt
    25021 atataagttt cagtctattt taactttaaa taagttatat ataactcatt ttacaattaa
    25081 aataagtcta aatcaactta aagtaagcga aaaataaata taagaaaatt gaaaacttat
    25141 tagtattatt ggaaagacta gggttttaga gtcgatatat attggtttaa gatggcataa
    25201 tttttgctta aaaagaagag tgtaaattga ctaaataaaa atagaaggga atttaaaatg
    25261 ggagaaaaaa gtaaagggta tgtatttata gcaatagcag ggttattatg ggctacactt
    25321 ggattatttg gaaagttttt aatgggaaat ggactgacat cagaacaagt agcatttaca
    25381 agattgtttt ttggatttat agttttaggc gtatattcat ctataaggac accacaaatc
    25441 ttaaagataa gcaaaaaagg aattatatat tcagtaataa taggaattat atgtcaggca
    25501 atgtttaatt tatgttattt taaagcaatt gacattgcag gtgtatcaat tgcagcagtt
    25561 ttactatata catcaccact gtttttagca atattttcaa aagtatgtta taaagaaaat
    25621 attactagaa gcaaattatt ttcacttatt ctttgtttta ttggtgcaat tatggcagtg
    25681 actggtggac gtttggattt tcaaggttta aacgcttttg gacttttact tggggtatta
    25741 tcagcaatag catatgcact tatgccaact attagtaaaa atgctttaaa ggaattttca
    25801 agttcaacaa tattagtata cagtttctta tttggagcta tatttatgat tccttcttcg
    25861 agaccttggg aaatcttaaa ttatgctaag gatttagatg ttttatcttg tatgctaatg
    25921 ttaggcattg ttccagctgc acttgcatat attttttatg cagcaggtat atctaaaggt
    25981 gtagagttgt cagttgcagg tgttgtggca tcagtagagt tagttggttc agtaataatt
    26041 ggttgcacta tattaggaga aagtttttcc ttagggaagt tatttggagt gatgttgatg
    26101 ttaatatctg cagtagtagc acttaatctt tcttatgatg aaataagaat attttataaa
    26161 tccaacaagt taaagcagat tgaaaaaact gaaagtattt agaattatat acttaaaaag
    26221 gatttattgg tatacatttt agaatccaac aaaaattata ccaaattata tttggtatta
    26281 aaaaataact atttataaat tttatagaat aaagtggaca gtacaaataa aatataagta
    26341 gatacagttt agactatcta ttttttatta tatattgtat aaatgtacaa attaatattt
    26401 tgttttgtaa atactaaata actatagaaa ggactatatt tatataacca tttctatagt
    26461 tattattttg tattaaacaa acttacagcc ctgataagaa tttctagcct ttaaagtatc
    26521 atcaatttga tttaaaattt cccatttttt taggctccat ataggaccta ctagttcatc
    26581 cctcttacca tcaccagtga gtctatggat tatcatagtt tcaggaagta tttctaattg
    26641 gtcacagaca agattgatat attcatcttg ttccataaga gttaacatac cattttgtaa
    26701 catcttttcc ataggagtat cttttataac atgcaataga tggattttta taccgtctac
    26761 acccatttta ccaactgcct ttgctgtttc catcatcata ttataatctt caccaggaag
    26821 accatttata atgtgtacga caacctttat atttttagac tttaattttt caacaccttc
    26881 aacaaatgtt ttataatcat gacctctatt tataatttta gatgtagaat catgaattgt
    26941 ttgaagtcca agttcaaccc ataaattggt tcttttattt agttcagata agtattctac
    27001 aacatcatct ggcaaacagt caggtcttgt ggatattgaa agacctatga catcttcaag
    27061 ttctaatata gtctcatatt tttcttttaa aacttcaaga ggagcatacg tatttgtata
    27121 ggcttgaaag tagccaatat actttgcatg aggccatttt tttaacatca tttcttttat
    27181 attataaaat tgactgataa gattatcttt agggtttcca gcaaaatcac ctgagccttc
    27241 tttgctacag taggtacatc cgccataacc aagacttcca tcaatgtttg ggcaggtaaa
    27301 tcctgcattt atagatacct taaaaacttt ttctccaaaa gtatttctaa gatagtaatt
    27361 ccaagtatga tatcttttat catcaaaagc atatttaaat ttatccaaaa aaatcaccta
    27421 tttctaataa aattgtacgc tgagcttgta caaaaaacat attaccacaa atagataact
    27481 taaacaaatt ctattttaag taatataaaa atacagcgag aaaataatta atattttctc
    27541 gctgtatttc cagagaaaaa tagaactagt ccaaataata ttatgaaaaa agacattatc
    27601 gatactataa atctagataa aaaaagtgga gataatataa ggcatatacc aaatagaatc
    27661 ttaactatat tccaagttgt aaatttagaa taaggattat tcttactatt tacaagtgct
    27721 actagttgat taaagattaa ataaaaccct aaaaataatg aaaatatgct ttgtattttt
    27781 tgaggaaata caaaaagtaa tatacatgca attattagaa cccattggat attaatagag
    27841 ggtttaattt cttctttagt agcatatctt tttagttcat taatattttt taaatttaaa
    27901 tatgcaaaga ataaaagtgc aataccaaaa gtccaagaaa ttaattttat acctaatgtc
    27961 ttaaatgtaa ggcataataa tcctaagata atgagcaata ctcccattaa cataaattta
    28021 gtagcatttt cttttttatt aaagttatta aaatcgatat taaaatttgt gtacataaaa
    28081 tcacctccaa aatcgataga acaattataa cagaaattca tatccaaata aagcctagtg
    28141 tataaaaatt aaactatact tagtaattaa ttaataggtt gtatcataga cttctattaa
    28201 tagaattata tagaaggagg tttgtccatg acaaaattat gggcaataat atttgcatta
    28261 ttagcaggtg gttctacagc tcttgaagct tttataaatg gagaactagg aaaaagtaca
    28321 acagcattag tggccacctt tataagttta actgtaggag caatattttt tttggcaagt
    28381 ataatagtta caggtgactt aaagtgtcta gtatctataa atggttttaa ttataagttg
    28441 ttattaggag gagtatttgg aggtttaata atatatttta cagtaaaggc aattccaaat
    28501 ttaggagtat caaatacact tatattaaca cttgtatccc aagttttagt tggatttttt
    28561 attgatagcg taattttggg acaagaaaca atgcatttat acaaatacat aggggttata
    28621 cttttaatat tagggacatt ctttatagtg aattaacaat ttaatataat ttgctatgca
    28681 actcaaaaat ttggtataat tatgttaata aaacaaagtt agatgaaaga ggtgttaaaa
    28741 ttggctgatg aaaaatttgt aatgtcattt agtggtggta aggatagtat attagcatta
    28801 aatcgaatgt tgaaaaaagg atataagcct gtggcactct tgacaactat aagtgaagaa
    28861 catggaaagt catggacaca taatttagaa tataatatgc ttaagcaagt aagtagcaat
    28921 ataggattac ctttattagt tgctgagtgt ggtgtagaag gatatgaaga gagctttgag
    28981 agggctttaa taaaagctaa aaacatggga gcaacgatat gtgcatatgg agatatagat
    29041 atagaaagtc atagaaaatg ggatactgat agatgtgaag cagttggtat gaaagtagat
    29101 ttaccattat ggcaagagag tagagaggat ttagtatatg aatttataga cagtggattt
    29161 tgtagtgttg taacaaaagt aaacttaaag cacttaggag aggaattttt aggaaaaaaa
    29221 ttaactagag aacttgtgga gaagataaaa aatgctggtg cagacccatg tggagaacat
    29281 ggagagtatc atacatttgt cgtagatggt ccaatattta aaaaacctgt agaatatgaa
    29341 gtaaaaggaa ctttaataaa agatggctat ggatatttag aaataaaata attacataaa
    29401 taaaatacct attatataat cctaattttt gcaaaggtct aatatttgca agattgtata
    29461 ataggtattt tttatttaga tattttcata tattgctact cttatcatct aagcaacctt
    29521 atttagatta gagtctaatg tagaaaaatt cttttttaga aaaactaatg ataaaataag
    29581 acatataaac tcagaaacaa tagtagtcat ccatattcct tgtccaccaa atattagtat
    29641 cattgaaatt agacttaaaa caactattac aagccctcta ccaagagata taacagtaga
    29701 aattgatggt ttttctactg atacaaagaa tccagaaatt attacattaa ttcctaccaa
    29761 taagaaagat atagagaata ttttaaatac acgaactcct tcattgaata gcattgtttc
    29821 ttctgggtgt ataaataaag agactattgg tcctgaaaaa gccatacaaa ttgcaaatac
    29881 agcaactgat gctattattg tggcttttat ccccattttt aataattttt ttacattatc
    29941 tatatttcct gcaccataat aaaagctagt aagtggttgc ataccttgag ttatacccat
    30001 catagtcata agtactaatg tatttatata atttatgaca ctataataaa taagagcatt
    30061 ttctccaata tatttagtaa gacttaagtt aaaaagtaaa acaactatac cacaacttaa
    30121 ttcagtagtt gaatcaggaa aacctataaa tacaattttt ctaagtgtct taaaatcaat
    30181 tctaaatttt gaaaaattca aagtagagtt ttttcttaaa aaatgtatta agaagaaaat
    30241 agtagaaaag acttgagaca aaacagttgc aataccagca ccttttacac cccatccaaa
    30301 ttcaattaca aacaagtaat caagtatgat gtttgtaaga gcagatatta ttacaccaac
    30361 agtagctaat attggaaagc catcagtttt tattataact tctaaagaat aagacactat
    30421 aaagaatccg ttaaaaaata ttattattcc taaataatct ttaaccatac caattgtaga
    30481 ttctgtagct cctaaaaata gtgctaatct atctaaatta aaaaaagtta tagctaatat
    30541 aattattgat aatataatta ttgatactaa gttaaatgaa aagacttcgt tagcagattt
    30601 aatatctttt ttccccagat agattgcaat tatggtagat gcaccagttg aaaataatag
    30661 agaaactgca aatataaaat taataaaagg cattgatata ttgacagcag ctaaagccaa
    30721 ttctccaact cctttactta caaatattcc atcaaccatt gtatatagtg agaaaaccca
    30781 cattgcaact acagatggtg ctaggtattt aaaaaatctt ttacctagac tcatgttttc
    30841 gtttatagat atttttgtat ccatttatta tcactccctg taaatctatt ataaaattac
    30901 gaaactatta attaataatt ttatttctaa tataaatgat aaactatggt ataataccaa
    30961 tgtcaacagc aaatagtata taattataaa ttttattaaa taatagtgat tttaagggtc
    31021 ttataaatat atcttattta tatattactg acatttaact gacaaatagg aaaaaggtac
    31081 tttaagtgac atttaactga caaatggaaa aaaagcactt tgagtgacat ttaattgaca
    31141 taaaactgaa cattatttga atagtatttt gcttatattt tcagatgttt ctttatccat
    31201 ttcatctaat aagtgagaat atcgaatatt tattcatagc tatttttata tctgcatgta
    31261 ctaatatttt ataaatagct tttatgttag tacctgaaag taatatcaaa gtcgcatttg
    31321 catgtattaa ttcatgtact tttatatctc taggattatt atctcttaat agttttttaa
    31381 aatgaacaac aaaagttggt tgaactcacg ggttgaatct tttatttaag catatcaaat
    31441 caaattcatt tttcaatata ccctgtaatt ttaacttatt ttgttttaat ttttgccctt
    31501 taagcaaact tataagttca tcaggagcaa ataattttct tttggatcta gggattttag
    31561 ggtctttgaa gattatttta ttgtatacat aaactaatgt ttgatttaca tgtgagattt
    31621 tttatcaagg tctacatctg accatataag tgatacagct tcaccaaaac gtaatccaag
    31681 agttagtatc aaaaaaattg gtatacctat aggaatattt tttgattttt ctaataataa
    31741 ttgagtttct tgctttgtat aaaacttaga agttgaacta ttttttttga ttggggttgt
    31801 aacaaaatca caaatatttt ctgatatttc ttttaatcta taagattctt tcaatactga
    31861 ttttataaaa tcgacttggt tttttattga atttaacatg tgctcattgt atatgttatt
    31921 tatataagac tgtaaaatag aaggcgttat atctattaat ttcatatgtt attggaaaat
    31981 cgaataataa taacttggta ttcgaaactt ttgataaagt aataaaacta catccaaatg
    32041 caaaacctgt ttttcatagt gatagaggtt ttcagtatac tagtaaggtg tttgaatcga
    32101 aacttttagc acaaggtatg atacaaagta tgtcaagagc tggtcgttgt attgacaatg
    32161 ctcctatgga aggaatttgg ggaattttaa aggtggaaat gtactattta aggaaatttg
    32221 atacatatga acaattagtt aaaataatag agacttatat atattactat aataatttta
    32281 gatatcaaaa gagattaaat tctatgtctc cacttgaatt taggaaatat ttaagtacag
    32341 agatagcata atttatttta agtagctcta aaaaaattta aatatctagg gttttatttg
    32401 acgtgctctt ttttagatag taaactttaa aatatagata ttaattatat gaatataata
    32461 aaaaaagtac taatgagtta cactagtact ttataactac ttttacatgt tttaactgta
    32521 taaaacagtg ggtatagttc agcaggagtg actttagttt tgaactaaaa atcaagttca
    32581 aaaagaataa acattagtat ttgaacttca ctctacgtct aaatagattg tagttcttct
    32641 tgtttttatt ataccacaaa ttggtacaga tattcaaaaa taatatattt atgatataat
    32701 aaaaatgtaa atagttttgc agtgagcgat atttgttaca aagtagggct taatgcttga
    32761 aatataaggt gttgagggta tatgataaac tttatcattt gcactactca tggttcactg
    32821 caaatttaag agagttgcac atgtgtaagt attgaaaatg cccagtttat tttggggtaa
    32881 agttttatat taactaagtg gtatggaaag aggtttttca gaagtatatg tacgtctata
    32941 ttgtaaagtt ttatattaac taagtggtat gtaaataagg aaggtggaag tcaatatgca
    33001 tgggtcaaat gggttttata ttaactaagt ggtatgtaaa tacgaaatta gagtttgaaa
    33061 tatatgacta cataatagtt ttatattaac taagtggtat gtaaatttgt gtcacatcat
    33121 tgtcacttct ttagaatatc aaaagtttta tattaactaa gtggtatgta aatttttaag
    33181 caggtgatta aatgattaaa aaagtagaaa agttttatat taactaagtg gtatgtaaat
    33241 aataacttgt caatgtagtt atatgcaaca acttctatgt tttatattaa ctaagtggta
    33301 tgtaaatgaa ttatatatta tgaaaaaata tggagtcaca gagggtttta tattaactaa
    33361 gtggtatgta aatttgcagg ttttccttat agtttgccat atgttcctgg ttttatatta
    33421 actaagtggt atgtaaatta ctttagcact agtaaaggta gaattattaa agtgttttat
    33481 attaactaag tggtatgtaa attcgaatgt gaatggcact tctatttctc caacttttgg
    33541 ttttatatta actaagtggt atgtaaatag tataatgttg aaaagttaga gagtacaatc
    33601 aagaaatttt acattaacta aaatgtatag aataaaacat gtatttatac ttaaattctg
    33661 tacctatata aaaaagtgaa ctctgtcaac aaagcacttt tttatataga taaattatca
    33721 ttttatttta agatagaaga tactaatgct aaatgtttat cattagtatc tgtatgtaca
    33781 taaaagttta attttttata taaatttgat ctttagaaaa atgagcagta tcaataaata
    33841 tattgtctaa attttttcta ggaactagtt gactagctat aagattagct tcaactcttt
    33901 gattgttaga ctatgaaatt aaatctaaag gttcattctt ggtcgtataa atagctttat
    33961 cattcgtatg tactataaca atttttgcca tctgcttttg atagataaag agctttatca
    34021 gctttagaaa ataaatcttt atataattta gttgaatcat cagtgaaggc aataccaata
    34081 cttaatgtta ttttatgatt gtcctttact tttattttac ttgcatcatt taaaatatca
    34141 ttagtaattt ttattattaa atcctttgtt aatgatttta taaatattgt aaattcatct
    34201 ccaccaattc gagcaactat gtctttatca tgtgtgttat gtaatagtat ttttgataca
    34261 gcaactaaaa cttcatttcc ctctaaatgc ccaaaagtat catttacagt tttaaaatca
    34321 tcaatatcaa taactaatag agcatcatta tttttggaat cagaactaca tagatactct
    34381 tcaataagat tttgtgatac tctttgatta tataattgtg ttagtgggtc acgttgagcc
    34441 tgattaatta agctttctaa tttagattta tcttcagtta tgtcttttaa aacgcctatt
    34501 gttttgatag ggttatggtc actatcatat ataactgaac attgaacacg aatccatctc
    34561 cattcatttt tagttaatga atttacttgt cttatctcaa ttgtttcacg aagatttcca
    34621 tgaagtactt ctagtagttt tccaatatca tcaaggtgaa taattttacc agattctaat
    34681 agtttggagt aattttttgt ttcaaaattt tctaattcaa tttttttgtc aatttctaca
    34741 cgttgatatt ttataagggt atcgttttca atatcatact caaacatgat atctgtaata
    34801 ttttgcaaag caatacgata tcgctctctt tctaatttta gttcagattc tatgtttttt
    34861 agttgggtta tgtcagtaat aatactatta atttttacta tgccatcact atttaacgat
    34921 ttcattccag aatctaatac ccacattaat gttccatctt tttttcggat tctatattca
    34981 gatgaatatg taggtccttt tgcaaaacat cgttcacaat cttctagtgc tttaggtaag
    35041 tctggtggat atacagcacc cactgctgaa ccaccactca tttccatgaa ctcatcatat
    35101 gtgtatccta atattttggg caatccctca ttgacataga aaaatgagta tgtactatca
    35161 tcattgctac cttttaagcc accattgata ttatttgtaa tcatttcaat aacttctgtt
    35221 ttttccttta gtaatctttg caaataatca taactttgag ttccaatttt agtgggaaag
    35281 tattcatcaa gttgcatttc accataaggg tttgatatgt gcatgtgctt tactaataat
    35341 tttcctctat cctcaattat ctcaaatgta caacgttgat ttacctctaa aatcatttga
    35401 gcattttctt tagttcgaac agtatatctt cctaatacca tacatctatt ctcatcttca
    35461 cttacagttt caaatacatc attatttata tcacaagaag gaatttcatc ttgacctgca
    35521 taaaaataat tttttatttc attaaaagaa gtgagaaatt cctgttctcc tggtccaatc
    35581 catgtaacat tttcacaaag gtattttaat acttcattga tatctcgatt tatataaaaa
    35641 cttgttataa tatgttttgc taatttgggt gcttttttta ggagtatgct catgatattc
    35701 ctcctttctt tttgctatta tattttaatt atattataca tcaatatatt taaattaaaa
    35761 gctttgttaa actatgatat ctttgtcaaa taagttaatt ttaacaaaaa agaactgaaa
    35821 caatatatgc ttcagtactt aatgtcaata tcttgtatag atacatattt ataaactaat
    35881 gtacaagttt aaaaaaagaa agataatttt aatttatttt aaaataacaa tgttaataat
    35941 catttttatc aaattttttc ttgtttttct ccttgttttt atacattttt ttatccaatt
    36001 caactattgt caattttaaa tttcttttta ctgtatcaac accataacta aatgaaagat
    36061 acttatattt agagaatact tttaaaaaat tttctcttaa ggcttctagt tgtgaataaa
    36121 cataattttt gtcaacatca ctagagaata taacaataaa ttcatctcct cctaatctta
    36181 taatagaagt agaatttatt aattctttat ttaaaagtga aacaaaatca cataaaatct
    36241 tgtctcctac attatgacct tcatagtcat ttatcatttt gaaattatct aagtcaatta
    36301 gtacaatata atctcctata aatatgtcaa atctatcatt taaatatttt ctattatatg
    36361 ctccagttaa tgggtcagta attgagtagt gaagatttct cttattttct tcatagagtt
    36421 ttgttatatc attggccata gtaattatgt aggttttttc atcaacatct actttgtatt
    36481 ctaaaacatt ccaatagctt gtagtatctt ttttaaactc taaaatccaa tttgaaattt
    36541 tatcataagg ataatttttt tcccaatcta attgaatatt gtgagaatcc gtaaaaaatt
    36601 tagcaatatt atcagggagt ttcttagcta tttctatatt agtcattcca agtggattat
    36661 cttgcatata acttttaatt aaatttttta aattatcatt tataaatata attctgtagt
    36721 tagaatctct tataattaga aatcctggaa aagttcttaa aaaaatttct ttaaacatat
    36781 taatttctcc aaaataaaat actttgtact agatttttgt taaatttttt attttattta
    36841 catctacata cataccttgg gcaatcgacc ttccatcaat tgcagaaagg ttacattgtg
    36901 tatacataac tgtgacaatt tgaccatctc gttttatgaa tctatataaa aatggttcaa
    36961 ttttatttgt gtcaatcata tccaaacttt ttttataaac aaagtctaaa tcatctggat
    37021 gaacaattgc tcttaaattt ccgcccatct caccaaaaaa ctgttctttt gtataaccta
    37081 taatgtcaaa catttcttca ttcatataag taataatcat atcaccaaat aaatcgtagc
    37141 gaattatacc tacaggcaac attgaataaa attgtgataa aatattactt tcatcaagat
    37201 gtgtatttgt cattttaggt attgaatatg attcaaattc atttatatag ccagcagttt
    37261 taattaaatc caaatgtaat tttgctaaga gtaatttatt ttctgaaatt atacaatttg
    37321 cactaaagta gaaattgcta tatttttgat gttcagaagc ttcatctgat aaaacggctt
    37381 ctccactaat taataatgaa tctgattcag tattatgtgg ggttatactt ttgtaaagaa
    37441 tagaaaattt tttaccttta atatgttttt caaaatgttc tattacttta ggaaaagatg
    37501 taatttcagt tttgttgtaa aaatcaaacc attgaatgtc ttcagtgaca ttagctctta
    37561 gttttttcat atcttgcata ataaaaaatc catcaaatat cttctctatt aaagattttc
    37621 ctatatcaga atattttata aacattttct ctgaattatt ctctttagat agtaattttt
    37681 caaattcttt gcactccatg ggttttgcat aataataacc ttgggcgata tcacaattta
    37741 tacttttaat aaattctaca tgttgttctg tttcaacacc ttcacatact gtaagcatcc
    37801 caagagctct tgcaatgttt attatagagt acaaaatggt tgtattttta aaatcattta
    37861 aattatgaga taaaaatatc ctatcaattt tgattatatc aaaaggtaga ttttgcaaca
    37921 taccaaaaga tgaatatcca gaaccaaaat cgtccattga tacagaaaaa ccataagaac
    37981 gaagttcagc tagttgttga ataattgtat ttgtattttc tattaatata ttttctgtta
    38041 tttcaatgct aaaatttgat gtagagacgc tgtacttttc agtaatacct tttagcatac
    38101 ttggaaaatt agggttaaaa aaatgaagac gagaaaagtt acaacaaatt ggaacaaaaa
    38161 catcattgtt atcaatccat cttcttatat ttttacagtt ctcttcaaat aaatgcaaat
    38221 ctaattccgt tatcagacca aactgttcaa ataaaggaat aaatttatct ggagtaagaa
    38281 gtcctttaat agggtgtctc catcttgcaa gtgcctcaca tccaactata gtattatttt
    38341 ttatattata aagtggttgg taaaatactt caatttgttt agtttgtaga acatgtgata
    38401 tttctgataa gaactcctta tcattttcta atttattgta aaaactatta tctttaaaat
    38461 caaatagaat gtatctattt ttgccttcac ttttagcctt ttttaaagca ctatatactt
    38521 ggttgaaaag tatcaaagta gtcatgtttg gttcaccatt ccagatagtg ctgccgatac
    38581 taaatgtaac attggagtat atttcttttt cattaggaag tcttattttt aattctcggg
    38641 agctctctat aatagttgca cccatattat ttaactcttt atttgataca tttggaagta
    38701 caattaaaaa accttctcct tttaaataag cgactattcc ctttgattct ggaataaagt
    38761 gcaataggtt ttgagttaga gtaattaata aattttctcc gactagatat ccatatatat
    38821 cattaaataa tttaaagtta tcgatattta ataacatgat tcctatatgt atatttttcg
    38881 aaatacagtc atcaatatat tggtacataa attctctgtt tggtatttta gaaaaaaaat
    38941 ctatttcatt taaggttttt aatttaaaat ttctactatc taattcctta gataatactt
    39001 ctaccttttt atttaacatt tttatataat tatgattttg catggtattc ctccataaga
    39061 tactttaaat tttgatgaca actgtattta tgctagaagt atttaaatgt taatttgtaa
    39121 ataatttaaa tgctaaattt taaataagta tttaaaatga atatacatta agttatttgc
    39181 tccaatgcta caaatacaaa tattttttag tttagtaata atattagata aaattagtta
    39241 atgcttaaat tatagtatat tgaaagattt cctttttgaa tgcaattata tcatattttt
    39301 tcataaatag atagattgtg agctgtatag ttagtaaggt agagtttttt tataattaat
    39361 tttaagttta atgatttttc aaaggcataa ttattttatt cataattaac tttttataca
    39421 taatttaata ccacataatt aattttagtt attaaaatta agtttatt
//
LOCUS       DAMJYN010000034        38483 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.035, whole genome shotgun sequence.
ACCESSION   DAMJYN010000034 DAMJYN010000000
VERSION     DAMJYN010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 38483)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38483)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38483
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.035"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            185..391
                     /locus_tag="PC466_001842"
     CDS             185..391
                     /locus_tag="PC466_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769228.1"
                     /translation="MSKYSSLWEYVKKNNSQSFKLTFEEIKDIAGIEIDHSFLKYKKE
                     LNEYGYQVGKISLKEKTVIFNKID"
     gene            complement(702..1445)
                     /locus_tag="PC466_001843"
     CDS             complement(702..1445)
                     /locus_tag="PC466_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase"
                     /protein_id="HDF2769229.1"
                     /translation="MNFLSDLHTHSIVSGHGYSTLLENINYCKENGIKILGTSEHGPK
                     MPGSPHRWYFHNIQNIPRIINNIIILRGCEANILDIKGNIDLEPFVIPRLDYLILSFH
                     EAVFSPNTLENNTKALINAINKHDNIEILGHLGNPNYPIDYELIIKLAIEKNILIEIN
                     NCSIKGVSRNGSSDNCKYIATLCKKYGAKIILTSDAHICFDIGNYEYSENILKEINFP
                     DELIMNYPKKLINHFHQKGKLLDVDYTNI"
     gene            1611..4178
                     /locus_tag="PC466_001844"
     CDS             1611..4178
                     /locus_tag="PC466_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2769230.1"
                     /translation="MTQKKLSRKEKVLICLKRLTEEHLNFNNGIRFGFDAEYIATEVG
                     INRSNASKELNQLIKESIIIKIKGKPVQYLYKESIESILGKKLNKGIFDNINSINEYS
                     ENDSIKDEYILESIKKENNIFNLVGCDGSLRSQIEQAKAAVIYPPKGLSTLIIGPTGV
                     GKSIFAEYMYKYSLTIKEDSDNAPFIIFNCADYSDNQQLLLAQLFGYVKGAFTGADKD
                     KYGIVHEANNGVLFLDEVHRLSAEGQEMLFLLMDKGIYRRLGEANKVHECRVMIIAAT
                     TEDPETAMLETFLRRIPVTIKIPSLEERGFQERMKLICYFFKEESVRIGVKLKVSKEV
                     IKAFILYKCKGNIGQLKSDIQLICARAFLDYMTYKRECVYVRLSLLPNNIRESLYGNN
                     RKEEFVQNFSFIGKDDIIFLPEEKDFESENLLIENKKYDLDFYGMIKETWNKLQQEGI
                     KESQIRSVIDGDIQKYSYNLMNTFIYNNSNQTAYNNIVNDSIATTVKYILQKHDKWSK
                     REGLDKLIKAIALHIQNLIERIKIGNIVKHPNKDEIMKERAYEYNIAKEILSNMSLMY
                     GVEFPEDEAIFLATFLYLSYVGLNEESIAILVIMHGESTASSMVNVANTLLDCNHAVA
                     INMGLEDRVQDILVQAVEIANKIDKGKGILILTDMGSILTFAKVIRDATGKEVKAVDM
                     VSTPIVIEATRKALTPEMTLEKLYFNIIESIKKHYGDMEVTYAEKDNGGRYFDRLLID
                     NISKTLTFLNGEKAYFILKEVINRISEHYSLVIQDELLVKFIFHCSCMIERVIIKESL
                     VYKSYEERISRNKELYLVIKESFKLVEETFDIIISDMEYANILDIFESQYDTDKFKS"
     gene            4408..4812
                     /locus_tag="PC466_001845"
     CDS             4408..4812
                     /locus_tag="PC466_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2769231.1"
                     /translation="MIGIIVMTHGSFSEEIIKSCELIAGPAERTAAIKLNRNDNIEDL
                     NKNFVEKLNELDEGDGVLVLADLLGGSPSNVASLNLKKGGKFHALTGVNLPMLLEALI
                     NREGKSLEELAEACIEAGQTGINNINKVLSSM"
     gene            4836..5333
                     /locus_tag="PC466_001846"
     CDS             4836..5333
                     /locus_tag="PC466_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2769232.1"
                     /translation="MSLVKYCRCDDRLIHGQVIYKWVKHLGVKKIVVVDDETTNDVIA
                     KGLIKMAAPKNIDLSILTVSESRRYFYNNQADDNVFVLIKNLDTANRMIEEGINIKKL
                     IVGRIPTGIGKKKISQNVYINKKEFLLIDEFIKKNINVSIQMVPDEEEVELNQNINRY
                     KGEFI"
     gene            5336..5737
                     /locus_tag="PC466_001847"
     CDS             5336..5737
                     /locus_tag="PC466_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIC"
                     /protein_id="HDF2769233.1"
                     /translation="MNKYKVIILCHGTWGKVLVEETNKNFGLSNQYEVLSLSSEKDVS
                     VFMKEVEEVVDKEDVKIIISDLYGGSTSSVAIAVAIRRGIDAINGLSLQTILIVDEEL
                     SKEDKLHTLPERIVKKNNNLCVDLIKEFKKI"
     gene            5755..6243
                     /locus_tag="PC466_001848"
     CDS             5755..6243
                     /locus_tag="PC466_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2769234.1"
                     /translation="MAKITLVRVDHRLIHGQVITKWVKIAQAQKIIIVDDFLGQDEFM
                     ADIYKMAAPSGVEVVILTAEDAGQAFQNNTLGDKNIFILFKNVDMANKAYKAGLKYEK
                     IQLGGIPNEAGKKMVFTAVSLGNEDVEQLNELNENGVEIVLQVIPEESSMTYENALKK
                     FK"
     gene            6270..7025
                     /locus_tag="PC466_001849"
     CDS             6270..7025
                     /locus_tag="PC466_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF2769235.1"
                     /translation="MESVLMLAIVTGLWYWFAAGLAGYTLFSTLKSPLFIGFSLGLLW
                     GDVTTGMIVGASIEMVYLGMVAAGGNIPSDKCLAALIAIPVALQTGVNAEVAVSIAVP
                     LGVIGVLVNNLRRTGNAVLVHKADKYAEEGNTKGIWRCATLYSLIFGFVLRFPIVFVC
                     NFFGADLVQSLLDVIPQWLMNGLTVMGGILPALGFATTIFTIGKNKFLPMFIIGFFMV
                     QYFEISITAAAIFGVCIALLITFMKEDKRVGEV"
     gene            7025..7888
                     /locus_tag="PC466_001850"
     CDS             7025..7888
                     /locus_tag="PC466_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HDF2769236.1"
                     /translation="MQEIKNKEVKNGQGPTEVNKTRVLTKKDVTKTYLRWWWTAELSN
                     SFERMQALAVCASFTPALEKLYKKKEDLVDALKRHLQFFNTQAIWGGLIHGTVLAMEE
                     EKATEGKIPGEVISGVKNGLMGPLAGIGDTLDFGTFQTIFLALGASFGAEGSVIGAFF
                     PIMFSILLFCEGYYLFHLGYSLGRDSIKKILSGGIVNKIIDGASILGMFMMGALSATT
                     VKLSTPLSFDIGGKAIVVQDTLNMIAPGLLPLGVVFFVYWGMKYKKWTITKLLVILVV
                     LALVGSFIGIF"
     gene            7935..8414
                     /locus_tag="PC466_001851"
     CDS             7935..8414
                     /locus_tag="PC466_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-2-amino-thiazoline-4-carboxylic acid
                     hydrolase"
                     /protein_id="HDF2769237.1"
                     /translation="MSEKMYTEKEYLEGIRGATGERAVWFYLLMKEAEKLGANPDDIC
                     KEAIYGFGKMRGQKYNVADTPGKMAEMLYNSKGQKVFEMELVENTDENGVLKFHHCPL
                     DAAWKEYGLTKEERKEICRLACYGDYGRVDCAQGVKLDFAQKCAHDDEVCELVFTKK"
     gene            8479..9786
                     /locus_tag="PC466_001852"
     CDS             8479..9786
                     /locus_tag="PC466_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HDF2769238.1"
                     /translation="MDISRSVDNSLNRTIEFLKELIKIDSQQGEPISQCPFGIGPKKS
                     LDKTLDYCASLGFSVKNIDNYIGYAEIGEGEELIGIPMHLDIVPPGEGWSVDPFSGAV
                     IDNIIYGRGVIDNKGAVSMLIHVLKNIEDMYPTINKRIRLIFGTNEETDMKCIKYYLD
                     KGEEIPSMGFTPDAMYPVVNGEKGRVHIRIEKEIKIDKSKPYIIVRGGTKENVVPSHC
                     TAKIINGIISELTTKGVAVHASNPEKGENAISKMVIKIVEDNMDFQHREDIELVSKYL
                     CSDYYGDALGINQYDEVFKNTTLNLGILKVNEEKIVCELDIRYGKNIVLNNIIDRFKK
                     VFCNGWKIEVIAHKDLHYVDESNLVLKKLLEAYEEVTDENGYTIAMGGGTYASWFKDM
                     VAFGPKFLAYKTGGHGVDERVPINHIRKNMEIYTLALIKLLEL"
     gene            10097..10237
                     /locus_tag="PC466_001853"
     CDS             10097..10237
                     /locus_tag="PC466_001853"
                     /inference="COORDINATES: protein motif:HMM:NF021468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2185 domain-containing protein"
                     /protein_id="HDF2769239.1"
                     /translation="MNGEGCILSNKITKECYKTGYMIREKSIDTYPDSGRGFMTWDEN
                     GE"
     gene            10749..11843
                     /locus_tag="PC466_001854"
     CDS             10749..11843
                     /locus_tag="PC466_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2769240.1"
                     /translation="MNELNIAKTLILKRKEKGITQDELANYIGVSKASVSKWETGQSY
                     PDITFLPQLATYFNITVDELICYEPQMMKEDINKLYNKLCKDFTVKPFDEVMDEIREI
                     IKKYYSCFPLIFRMGLLIVNHYDIVDEKKRELLISEALEIFIRIQETCNDIDICRQAK
                     SMEATCYILLNQPIQVIDLLQNSNFPMINESILLAQGQMMNGQMDEARETFQLGAYQN
                     LISLVQNLVGILQNADKLQMKEIERRILAISDIFELDTLSPAIMLSSYLTQTQINLIH
                     GDNEGAIKSLRKYVDLATRDIYPIIIHGDDFFNKLDRWISEIGTGITRDDTIVKAGIV
                     AAIKNNPMFSLLSENKEYKFLIEKLSLLEE"
     gene            11848..12048
                     /locus_tag="PC466_001855"
     CDS             11848..12048
                     /locus_tag="PC466_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLDc_N domain-containing protein"
                     /protein_id="HDF2769241.1"
                     /translation="MENLMEYLPLLIPVIILDLILIITALVHVLRHPNYKIGNKAIWI
                     IVVLFISLIGPILYFTIGRGEE"
     gene            12048..12965
                     /locus_tag="PC466_001856"
     CDS             12048..12965
                     /locus_tag="PC466_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2769242.1"
                     /translation="MNIVSINGLSKGFGNRKIIDNLNFTVPEGSVFGFVGKNGAGKTT
                     TMKMVLGLLEPDSGTIDVCGEKVTYGRTSSNRHVGYLPDVPEFYNYMRPLEYLSLCGE
                     ITGLSKKEIKIRSEELLSLVGLGNEKRRIGGFSRGMKQRLGIAQALLSRPKLLICDEP
                     TSALDPVGRKEILDIMLKIKDSTTVIFSTHILSDVERICDHVAILNKGSIALSGTLSE
                     IKSMHGKDRLLLEFASNNEIQKFKSSGGIKSLLKDSEETNMEIVLHGKDIKAIQKTVI
                     STLAEMNLCPVKMELIELSLENLFLEVVK"
     gene            12962..13720
                     /locus_tag="PC466_001857"
     CDS             12962..13720
                     /locus_tag="PC466_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2769243.1"
                     /translation="MREYIAFTKKEFKENIRNYKLLSLTILFLVFGIMSPLSAKFMPD
                     LIAHFAPTLKVTTAPTALDSWTQFSGNISGLGTSLTLIVFCNILSNEYSKGTLVIMLT
                     KGLSRSSVVLSKFSIAVIIMTIGFWLSFLCTYGYTMYFWPTANLNHIIFSAFNLWLIS
                     IMYISILILGCVLFRPAFASVLLVLAATAILSLISIPKQIAPYTPNFILSKNIDLVSG
                     KVTPPEFIIPIIVTIVISIVCLLLAVVLFNKKAV"
     gene            14103..15176
                     /locus_tag="PC466_001858"
     CDS             14103..15176
                     /locus_tag="PC466_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF362 domain-containing protein"
                     /protein_id="HDF2769244.1"
                     /translation="MEKSKVYFCDLYSNSQNKNVPNNVRRLFDEAGFKDLIEKNDQVA
                     IKLHFGEKGNTTYMSPVAVRQVVDKVKDCEGKPFLTDTNTLYTGSRTNSVDHLTTAIE
                     NGFAYAVVNAPVIIADGLYSRNYENVKIDKKHFESVKIGGEIYNSSAMIVMSHFKGHE
                     AAGFGGALKNLAMGCASAAGKQMQHSDVTPVVKEKKCVGCGKCVNSCPTKAISIVDKK
                     AVIDSDVCYGCGECPTVCPTRAVTIQWESDSDVFVEKMAEYAYGAVSNKKDKVGYITF
                     VMNVTPLCDCVPWSGRPIAHDIGILASTDPVAIEQACYDLICKEMGHDVFKHEHPHVN
                     GTRIIDYACEMGMGSKEYELIKL"
     gene            15246..15509
                     /locus_tag="PC466_001859"
     CDS             15246..15509
                     /locus_tag="PC466_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769245.1"
                     /translation="MKIYYEKENSKKANVNNIPSVFAFNFLRNFLTSKEYEETRKEYF
                     INNLTKSQVNQAMKDLKWLFREYEGLEVITMESLDGVKTRIVL"
     gene            15715..16692
                     /gene="bioB"
                     /locus_tag="PC466_001860"
     CDS             15715..16692
                     /gene="bioB"
                     /locus_tag="PC466_001860"
                     /EC_number="2.8.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin synthase BioB"
                     /protein_id="HDF2769246.1"
                     /translation="MEKYIIKLKNKVLREKEISYEEALNLISLDTNNKNDFDILLKSA
                     NEIREYFMGRKADLCTIMNAKSGKCSEDCKFCAQSSHYKTGVEEYSLLDYNEILNRAK
                     EMESKGVHRFSLVTSGKGMSGKEFNNILNIYEGLRENTNLKLCASLGIIDYEQAKMLK
                     SAGVTTYHHNVETCRDNFHNICTTHTYKDRIKTIKDAKKAGLDVCVGGIIGMNESEEQ
                     RLKMVFEIRELNVKSFPINILNPIKNTPMENYDVLEPMEILKTTAVFRFIIPNVYIRY
                     AGGRLSLKGYDKVGFNGGVNSAIVGDYLTTVGSGIENDKKMIIEQGFEL"
     gene            16920..17933
                     /locus_tag="PC466_001861"
     CDS             16920..17933
                     /locus_tag="PC466_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDF2769247.1"
                     /translation="MSITIKEIGELAGVSKTTVSKVINNKDENISQATREKILKIMKE
                     KNYVPNKLAQSLVTKKTNTIGLLIPDIRNPFFTDVSRGVEDKANEEGYNIILCNTDED
                     AKKEYEGIRTLSERMIDGIIFAASSNTNWKEANYKDIKIPTVLIDKKISMNKETLKGI
                     VKINNFEGAYIATKHLLDIGNKKIIYLSGPLQNEIAVDRLEGYKKALIECNLSYNSAY
                     VFEGKYKIEWGQEFIKNLEKIDFDAIFCANDLIAIGVIRGLKERGLSIPNDVSVVGFD
                     DIQTSSLISPSLTTVKQPSYDIGYKASEILINCLRGDKKESFDELIFKPELVIRDSTK
                     ESE"
     gene            17975..18865
                     /gene="rbsK"
                     /locus_tag="PC466_001862"
     CDS             17975..18865
                     /gene="rbsK"
                     /locus_tag="PC466_001862"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HDF2769248.1"
                     /translation="MGNIVVIGSVNMDMVCSVDKRPEKGETVLGNSFFTSPGGKGANQ
                     AISASKLGANVKMISCIGEDGLGEELIRNFRTNKVDYSLVSRNNHKSSGVAVITLCEN
                     DNSIVVVPGTNELVDIELIKKNEEEIKNADIVLLQLEIPLKTINYVVNFCFENRIKVL
                     LNPAPAVKLNEDIIEKVTYLTPNEHEYKIVFDTNEGIEEVLKKYPNKLVITEGKNGAR
                     FYDGEEIKHVSCISVDVQDTTGAGDTFNGALAVAITEGKKLYTAVEYAVVVSGLSVTK
                     LGAQSGMPYKEDVEKYLNNK"
     gene            18913..19875
                     /locus_tag="PC466_001863"
     CDS             18913..19875
                     /locus_tag="PC466_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HDF2769249.1"
                     /translation="MRVRKILSLGIAGILAIGMLTGCSMEGPSKSDNKGGSDKKDLTI
                     GVSTITLQHQFFIDIDEGIKEKAKELGVKVIVNDPDQDVAKQTSAIEDFIQQNVDGMI
                     VLGTDNSAIVPAVEGAFEKMPVVTVDAVLNTENITSYVGTVSYDAGKKLGEYTKKYID
                     EKLGGKSEIAIVTDLKSQIQMQRIDGFKDALKGSANVKILNSQPGYDREESLNTVENL
                     IQSNPDVDIIYATAENSVLGAKAALESAKNKDVKIVGFDLTEEASSGITDGTILAMIQ
                     QQPKEMGRLAVEAVVKAIKGEKVEKNIPVPALLYDKENIKDFKN"
     gene            19929..21440
                     /locus_tag="PC466_001864"
     CDS             19929..21440
                     /locus_tag="PC466_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HDF2769250.1"
                     /translation="MSNIILKLSNIAKEFPGVRALDNVNFELFHGEVHALLGENGAGK
                     STMIKILTGAHSKTSGKFIFEGKEIENISPDISKKIGINAIYQELTVFDELTVAQNIF
                     MGKEINGKVLTNDKKMNEEAKKIFDNMGIDINPNSLVKELSIAQKQMVEIARVLSSET
                     KVLIMDEPTSSISKKETEILFRLINDLKESGVSIIYISHRMEELFEICDRITIMRDGK
                     TISTLNTKDVSSEEELVNLMIDRKLDQFFPKRKVEIKEEIMRVENLTKNNVFNDISFN
                     IRKGEILGIGGLVGSKRSEIVEAIFGLRTYDSGKIYLNNEEVKFKTPSDAIENGLGLI
                     TEDRKGTGLFLQMSVKENTTMAGLKKISKFKSIIDRKKEKEILEKYIEALKIKTPHMN
                     QVIQSLSGGNQQKAIIARWLLLQPDILIMDEPTRGIDVNAKAEIYNLMGDLVESGVSI
                     IMISSEIPELISMSDRIMVMREGHISGFLEGEEMVENNVLKLAFGGKINEFNN"
     gene            21424..22422
                     /locus_tag="PC466_001865"
     CDS             21424..22422
                     /locus_tag="PC466_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose ABC transporter permease"
                     /protein_id="HDF2769251.1"
                     /translation="MSSITKHKEEKSSPLLTKLTSVFRDQGSAAVGLVIIFIIMSVAS
                     SNFLTLDNLINVGRQISINAILAVGMTFVIITGGIDLSVGAVIALVGTFWATTVVNYN
                     APIWVGMILALAIGTILGVIKGAIISTQKLPPFIVTLAMLTIISGASFVFTGGRPISV
                     NTDAFKMLGRGYIGPIPIPVIIMIIVVIAGHFLLKRTNFGRHVHAVGGNEEAARLCGV
                     KVNKVIVKVYALAGLLTALAGIILSSRLASGSPTVGDGAELDAIAAVVLGGTNMMGGS
                     GSIVGTCIGVGIIGILGNGLNLLSVSSYNQMIIKGLVMLFAIWINNIKLKKSAKSK"
     gene            22606..23868
                     /locus_tag="PC466_001866"
     CDS             22606..23868
                     /locus_tag="PC466_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HDF2769252.1"
                     /translation="MKKILLDTLNSKKQEYIDYLKELVSIKTEDVGHGILGGFEKEGQ
                     EYIEKLANYIGFSVDRQEMSEELIKKAKNIYKEGNLGHNYQDRYNLICKYSDDLPGKT
                     IVFNGHVDTMPPGDISKWKYNPYRATEDNGKLYGLGTADMKSGLIASILAVKLIKDSG
                     LNVPGNVKIMSVVDEEGGGNGTINAVMNGIGGDCCIICEPSEQNLIVAHMGFVFFEVE
                     VKGVSLHCGSKWEGVNAIEKAMLLLQDIKELEHNWLMIYKHPLLPSPTINLGVINGGT
                     AGSTVPDKCVFNLCVHFLPNIMSYEQVVNDVTNVIMTRANGDLWLKDNKPNINIYQSG
                     LGFQMDKDSDFVVNAHKILEETLGKKLEIKGSTAGNDARLMKNLAEIPTLILGPGSIE
                     QCHSIDEYVEIKEYLDSILMYASLILNL"
     gene            23888..24631
                     /locus_tag="PC466_001867"
     CDS             23888..24631
                     /locus_tag="PC466_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoplasmic protein"
                     /protein_id="HDF2769253.1"
                     /translation="MKKVLIVGESWVKNITHIKGFDTFVTTHYEEAVKWLKEAIESGG
                     YETVHMPAHVAADSFPYKLEELNEYDCIILSDIGSNTFLLSNSTFIDCNSNPDRLELI
                     KEYVNNGGALIMVGGYMSFTGIDAKARFGETAIKDVLPITMIDKDDRVEKPAGIIPEV
                     IDSEHPVLKGIPTEWPKFLGYNKTVARDNCPVLATIGGDPFVAVGEFGKGKSAIFSSD
                     CAPHWGPKEFTDWKYYNKLWVNMLDWLTC"
     gene            24804..26189
                     /locus_tag="PC466_001868"
     CDS             24804..26189
                     /locus_tag="PC466_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2769254.1"
                     /translation="MDNLNKKFLMEYIDEIQGELRDISDKIWKNPELQYKEYYASNLQ
                     KECLKKHGFSIEGLEGMDTAFVASYGEGRPVIAVLGEYDALDGLSQKVSTTKEPIVDG
                     GAGHGCGHNLLGTGSIGAVIAVKELIKLKKLKGTIKYYGCPAEEDLSGKVLMIKKGFF
                     DGIDCAFSWHPFDINTPIRIPTLANYSVKFRYNGISAHAAQAPYNGRSALDAVELMNI
                     GCNYLREHIFDNCRVHYVTTNGGKMPNIVPDFAEVWYYIRGVKMEHVRDVFGRIVDIA
                     KGAALMTGTIMEYDIISGVYDYIPNTILTDILSQNMKLVGVQNYNEDDYYFADKLAET
                     VSIDKRSSVSSVLSGNKDITKMNLHDEVTDDTFTHNNCISLSLDIGDVSYIIPTAQCS
                     CSVWPIGISAHTWQSCASAGSDMGFKAMLLASKSISCSINDVMLDELVINKAKKELKD
                     TVGSFEYTPII"
     gene            complement(26526..27170)
                     /locus_tag="PC466_001869"
     CDS             complement(26526..27170)
                     /locus_tag="PC466_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDF2769255.1"
                     /translation="MNNLDKNNVNEVLDMLLRTRRSIRSFTKEVPSKGLIEEIIETGR
                     LAPYAILSVAKQTDFRHFFVISNNSLQMNKIKTILVDVIKTQISVNEKKAKNNITLQS
                     FITSLKMQVEKGVLGIGTAPYLIIVAERRGIPPIEQKSLSHVMQNMWLKSTALGLGFE
                     LVSVIGRLSDNKDFCDILGVPTGEYGFDACAIGFPTTSVTREGRAIPHPSIKWI"
     gene            27434..28048
                     /locus_tag="PC466_001870"
     CDS             27434..28048
                     /locus_tag="PC466_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HDF2769256.1"
                     /translation="MKKVSIDRRTIRTKKMIRSALAELIDEKGFNNISVTDLTQRADI
                     NRGTFYLHYVDKYDLLERIENEIIQEIEEETKHLDSSNMMEIDTSSEPLPFMVKLFEY
                     FRKNSVIIKSILGPKGDPTFERKIKKFIETNLFEKQKLINFNIDEAIISEEYFIQYIL
                     SADLGVIQYWLEKNMKESPEEMALILARMSLLGPLRAVGIRKDS"
     gene            28269..28409
                     /locus_tag="PC466_001871"
     CDS             28269..28409
                     /locus_tag="PC466_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769257.1"
                     /translation="MKNENISYLALGLCFGVVLGSLFKNLAIGLSFGLVIGVVLDSKK
                     NK"
     gene            complement(28639..29086)
                     /locus_tag="PC466_001872"
                     /pseudo
     CDS             complement(28639..29086)
                     /locus_tag="PC466_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002599264.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            29856..30695
                     /locus_tag="PC466_001873"
     CDS             29856..30695
                     /locus_tag="PC466_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769258.1"
                     /translation="MFGYVKINKMDLTFREYDYYKAYYCGLCKYLKRNHGEISRFSLN
                     YDITFLIVLLTAVYNPESISTEEVCIVNPFKKKKVITNDITEYAASMNILLTYYKLED
                     NLMDDKRIKDKLAYYIYKNKLKLAYEKYPEKAEYIKQQLNELNKLEKDKNINIDEVSS
                     IFGNIMGEVFVYKKDENERNLRMIGFNIGKYIYLLDAYEDLDEDFKKGRYNPFIEYID
                     KNDELKEKVKKIIVTSLGFLARGIDNLNLNKNVGIIENIIYSGVYLRYINILESRGGK
                     NVQ"
     gene            30685..31128
                     /locus_tag="PC466_001874"
     CDS             30685..31128
                     /locus_tag="PC466_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769259.1"
                     /translation="MYSNTYNNENFMRARAFIENSEFKKAYDFLKTLTDKCAEWYYLT
                     GFSAMNIGYYEEGEDFLKRAKFMEPENSEYSDALRSYTQYRNDYSNRADNYNRRRRND
                     LDGCCCCCCDDCCCCLGDDCCENCAKLWCLDSCCECFGGDLITCC"
     gene            31139..31630
                     /locus_tag="PC466_001875"
     CDS             31139..31630
                     /locus_tag="PC466_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769260.1"
                     /translation="MSIKVAYGGVLLALNVILLTLTNIIPVNTLFIMGLASLLVSIVI
                     MEWGFKSGIAFYIGSIVLGFIVMASKSQWIVYSLTFGIYGIVKYLIEKDRSIYIEYFM
                     KLVFANIMILILYFLLRTIVYIPINIFIIGSFEIAFIVYDYVYSSFIGYYNNRLRKML
                     FKK"
     gene            complement(31832..32560)
                     /locus_tag="PC466_001876"
     CDS             complement(31832..32560)
                     /locus_tag="PC466_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family hydrolase"
                     /protein_id="HDF2769261.1"
                     /translation="MKNIAAFFDIDGTLYRDSLMVEHFKKLIKYDIIDQKNWYKHARD
                     TFMDWDKRQGNYDDYLLEICDLYVDSLKGLDKTCINFTSDQVIKLKADRVYKYTRSRI
                     EWHLNQGHIVIFISGSPGFLVEKMAKKYNVTDFLGSDYVFENNIFTGTVIPMWDSISK
                     NNAINDFVVKYDLDLSNSYAYGDTNGDINMLKRVGNPIAINPTKELLSQISLDEEISK
                     NVEIIVERKDIIYSLSTDVNIVDI"
     gene            32685..33773
                     /locus_tag="PC466_001877"
     CDS             32685..33773
                     /locus_tag="PC466_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769262.1"
                     /translation="MNFNFAKATNSRLMGSLGLIINWIDDENNHFCQYFLLDAEGLGL
                     ADYVSLNNPTQEEAYMEEERLMGGFGSDRVELTKDESLFLVSYFGNKNLYYDKLLPGD
                     KCEYIDIIKNYKTDLIIEKLYNKICKRVDEEVEFINYMTMRFIAWDRESLKYFSGSDE
                     IANMHITNINGTLLKNVVSDKGQGRYISEALYEDNDGYYICKIAFCISKCYETGFRIN
                     SLLVTDKELMYDFEVFDEISKSEFVSVYSVNSPEEFAGVFYRENPFLLKSNMNEGIFF
                     TRFNFNNDHVKENVYIINNDMKAIYYLMGNKFFIGTYNENDCNYINEISQSNYSDYIK
                     FEEKFFFEQNALYDFAESGSLDFDDFLE"
     gene            complement(34211..35059)
                     /locus_tag="PC466_001878"
     CDS             complement(34211..35059)
                     /locus_tag="PC466_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769263.1"
                     /translation="MSNKKKKDLDTSYMPYLDPANYADYITNEEIPQDELRNDPQISN
                     GYTKIPNNQNINNLYPNNVNHYPKSSNSPNNLPNTNNTSGNMNYNTSATNNMPNNMNN
                     NTGMPNNMSNNMNSNMGMPNNMPNNMNSNMGMPNNMSNNMNSNMGMPNNMPNNMNSNM
                     GMPNNMPNNMNSNMGMPNNMPNNMNSNMGMPNNVPNNMNSNMGYNMNNTMGIPNFSCN
                     QNMPPNVLMMIPGVICHNTMQGMPVVMPSTMPPNIYPTPYGSSNMSIQGIPQATNIEE
                     FDEEEM"
     gene            35258..35623
                     /locus_tag="PC466_001879"
     CDS             35258..35623
                     /locus_tag="PC466_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2769264.1"
                     /translation="MREEINDCNCNIVHEEIVTEAKSTMPDEEMLYDLAELFKVFGDT
                     TRVKILYALFANEMCVCDIASLLNMTHSAISHQLRVLKQARLVKFRREGKTVYYSLDD
                     SHISQIFDCGLNHIRETYK"
     gene            35646..38033
                     /gene="cadA"
                     /locus_tag="PC466_001880"
     CDS             35646..38033
                     /gene="cadA"
                     /locus_tag="PC466_001880"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HDF2769265.1"
                     /translation="MEANNLIKKEFILGGLNCAHCAEEINNKVSKLQEVKSSNLNFIN
                     KKLIVNIKESFNEDTTIEKIIDIIDSTEPGLDIQISSKENASSKTSIKKELILGGLNC
                     AHCAEEINNKVSKLKEVESSNLNFVNKKLTVNISNNFKEDDVINKIKEIINSTEPGLD
                     IQVGSTDKVKGRTTEKSGAVNDTNKKELVPLIIGALVYIFGIYQTATGYESQFSNIVF
                     IVAYVIVGGDVLLRAIRNISKGRVFDENFLMALATVGALTIGESSEAVGVMLFYKVGE
                     YLQGVAVGKSRKSITSLMQIRPDYANLKFNSEVKVVSPEEVNVGDIIVVKPGEKVPLD
                     GVVVDGVSMLDTSALTGESVLREVEKGDEILSGVINKNALLSIEVTKSFGESTVSKIL
                     DLVENSSIKKSKTENFISKFSRYYTPIVVIAALLIAFVPPLVISGEVFSDWLYRGLIF
                     LVVSCPCALVLSIPLSFFSGIGFASKNGILIKGSNYLEALRSVDTVVFDKTGTLTKGV
                     FNVTKLNPEGISEEELLEYAAIAEVNSNHPIAKSILSYYNKKIDLDTIDSYEEIAAYG
                     IRVKHNGNFILAGNEKLMKKENISYSSAKEVGTVVYIAVDKVYRGYIVISDEVKEDSK
                     NAIRSLKAIGVKEVVMLTGDNEKVAKNIAQELELDTVYSNLLPNEKVDRLEDLYEGRT
                     EKEKIAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVLMTDEPSKISKAIEIA
                     NKTNKIVWQNIIFALGVKIIVMILGAGGVATMWEAIFADVGVALIAVVNAMRAMR"
BASE COUNT        15008 a         3985 c         6887 g        12603 t
ORIGIN      
        1 taaaaaatat tttaactata attgattttt atttaatctg aaaaaaatat tatgactata
       61 aaaaattgct acttattatt tggatatttt tgtatataaa taataagtag catgacttta
      121 tacattaata atgatagaat ataaattaat agataagata taattttaaa aggagtgata
      181 taatatgagt aaatatagtt ctttatggga atatgttaag aaaaataata gtcaatcgtt
      241 taaattaact tttgaagaaa taaaagatat tgctggaata gagatagacc attcgttttt
      301 gaaatataaa aaagaattaa atgaatatgg atatcaagta ggaaaaatct ctttaaaaga
      361 gaagactgtt attttcaata aaattgatta agatataaat aattacatat aataaaataa
      421 tttgtattga cgattattac aaataaaaat aaagtaaatc ttatataaga tttactttat
      481 ttttagatga tattttttta gctttatact ataaggtata taaaactaag cctattaaaa
      541 atgttataat ttctattacc atcatagacc atatcaatcc atcaagttca taaaagtaat
      601 taagctttat taaatagctt ctttattata atttctttat ttcatataat ataaatagta
      661 ttaaaatttt tatgggagtt aaagtaagca tgtattatta cttagatatt tgtataatca
      721 acatctagta atttaccttt ttggtgaaaa tgattaataa gttttttagg ataattcatt
      781 attaattcat ctggaaaatt aatttccttt aagatattct cagaatactc atagttacct
      841 atgtcaaaac aaatgtgagc atctgaagtt agtatgattt tagcaccata ttttttgcaa
      901 agtgtagcaa tatacttaca gttatccgag ctaccatttc ttgacacgcc tttaatagaa
      961 caattattta tttctattaa gatattcttt tctatagcta atttaatgat taattcatag
     1021 tcgattgggt agtttgggtt tccaaggtgt cctaatattt caatattatc atgcttattt
     1081 attgcattta ttaaagcttt agtattattc tctaatgtat ttggagaaaa aacagcttcg
     1141 tgaaatgaca agataagata atctaaccga ggaattacaa aaggctctag gtctatgttt
     1201 cctttaatat ctagtatatt tgcttcacag cctcttaaaa ttataatgtt atttatgatt
     1261 cttgggatat tttgaatgtt gtgaaagtac catctgtggg gagaaccagg catcttagga
     1321 ccatgttcag atgtacctag tatcttaatt ccattttctt tacaataatt aatattttct
     1381 agtaaagtgc tatagccatg accactgact atagagtggg tgtgtaaatc tgataaaaaa
     1441 ttcatataaa ttcctcctct ataaaagatg agggtaacgt aatttatatt ataaaacgaa
     1501 taggaaagaa aatcaatagt tacataatta gacaaaaata ttaaaatatt gtagaattaa
     1561 gcttaataat aaatgtttaa cagtattact gcttataggg gaggttaact atgacacaaa
     1621 agaagctatc aaggaaagaa aaagttttaa tttgcttgaa aaggttaaca gaagaacact
     1681 tgaactttaa taatggcatt agatttggat ttgatgcaga atatatagct actgaagtag
     1741 gtataaatag aagtaatgct agtaaggaat taaatcaatt aataaaagaa agtattatta
     1801 taaagataaa gggtaagcct gttcagtact tatataaaga aagtattgag agtattttgg
     1861 gaaagaaact aaataaaggg atatttgata atattaactc tataaacgaa tatagtgaaa
     1921 atgattctat caaagatgag tatattttag agagtataaa aaaagagaac aatattttta
     1981 atttagtagg atgtgatgga agtttaaggt cccaaataga acaggctaaa gcagcagtaa
     2041 tatatccacc taaggggttg agtacattaa taataggacc tacaggagtt ggtaaatcta
     2101 tatttgcaga atatatgtat aagtatagtt taactataaa agaagatagt gataatgcac
     2161 catttatcat atttaactgt gctgattatt ctgataatca gcaattatta ttagcgcagc
     2221 tttttggata tgtaaaagga gcatttactg gagctgataa agataagtat ggtattgtac
     2281 atgaagctaa taatggagta ttgtttttag atgaagttca tagattatct gcagagggac
     2341 aagaaatgct atttctgctt atggataaag ggatatatag aaggttagga gaggctaata
     2401 aggtacacga gtgtagagtt atgataattg cagccactac agaagaccca gaaacagcaa
     2461 tgttggaaac gtttttaaga agaatacctg taactataaa gattccgtct ttagaggaaa
     2521 gaggctttca agagagaatg aagcttatat gttatttttt taaagaagag agtgttagga
     2581 ttggtgttaa gttaaaggtt tcaaaagaag ttattaaggc atttatttta tataagtgta
     2641 agggaaacat aggccaatta aaaagcgata tacaattaat ttgtgcaaga gcttttttag
     2701 attatatgac ctataaaagg gaatgtgtat atgtaaggct ctctcttcta ccaaataata
     2761 ttagagaatc attatatgga aataatagaa aagaggagtt tgtacaaaat ttcagtttta
     2821 ttggaaaaga tgatattatt tttttaccag aagaaaagga ttttgaaagt gaaaatttat
     2881 taatagaaaa taaaaaatat gatttagatt tttatggaat gataaaagaa acttggaata
     2941 aacttcaaca agaaggtatt aaagagtcac aaattagaag tgttatagat ggagacatac
     3001 agaagtattc ctataattta atgaatactt ttatatataa taatagtaat caaacagctt
     3061 ataacaacat tgttaatgat tcaattgcaa ctactgtaaa atatatttta caaaagcatg
     3121 ataaatggag caaaagagaa ggattagata aattaataaa agctatagcc ttacatattc
     3181 agaatttaat tgaaagaata aagattggaa atatagtaaa gcatcctaat aaagatgaaa
     3241 ttatgaagga aagagcatat gaatataaca tagcaaaaga aatattatct aacatgtcat
     3301 taatgtatgg agtagagttt ccagaagatg aagcaatttt tttagcaaca tttctttatt
     3361 tatcgtatgt gggattaaat gaggagagta tagcaatatt agtcataatg catggtgaat
     3421 ctacagcatc tagcatggtg aatgtagcca atactttact ggattgtaac catgcagtgg
     3481 caattaatat gggattagaa gatagagttc aggatatttt agtacaagct gtagaaatag
     3541 ccaataaaat tgataaagga aagggaattt taattttaac tgatatgggg tctattttaa
     3601 catttgctaa agttattcgt gatgctacag gaaaagaagt aaaagcagta gatatggtaa
     3661 gtacacctat tgtaatagaa gcaactagaa aggctctaac tccagaaatg acattagaga
     3721 aattatattt taatattata gaatctataa agaaacatta tggagatatg gaagttacat
     3781 atgctgaaaa agataatggt ggtagatatt ttgatagact actaattgat aatattagta
     3841 aaactttgac ttttttaaat ggggaaaagg cttattttat attaaaagaa gtaattaata
     3901 gaattagtga acactattct ttagtaattc aagatgaact tttagtaaag tttatatttc
     3961 attgttcatg tatgattgaa agagtaataa taaaagagtc tttagtttat aaatcatatg
     4021 aagaaagaat tagtagaaat aaagaattat atttagttat aaaagaaagt tttaagctag
     4081 tagaagagac attcgatata attatttcag atatggaata tgcaaatata ttagatatat
     4141 ttgaatcaca atatgataca gataaattca aaagttgata caaaatttaa aaatagccaa
     4201 aaggctatct tttttttact ttttttgata cagatttgat acaggttgaa aaaatctttt
     4261 gatacatatc gaaataataa gtttttaaaa aaaattgagt aaaaagtttt gattaaatcc
     4321 tgtaaaatag ccatttatta ttgatacaca taagttggca cggcaattgc ttatataaaa
     4381 agtgacaaga aaagtgaggt gaaattggtg ataggaataa tagttatgac tcatgggagt
     4441 tttagtgaag aaattataaa aagctgtgaa cttattgcag gaccagcaga aagaacagca
     4501 gcaattaaac taaataggaa tgataatatt gaagacttaa ataaaaattt tgtagaaaag
     4561 ttaaatgaat tagatgaagg tgacggagtt ttagtattag ctgacctatt aggaggttcg
     4621 ccaagtaatg ttgcaagttt aaaccttaaa aaaggtggca agtttcatgc acttactgga
     4681 gtaaatcttc caatgctact tgaagcttta attaatagag agggaaaaag tttagaagag
     4741 ttagcagaag catgtattga agcaggacaa actggtataa acaatattaa taaagttctt
     4801 agctcaatgt aatagaaaaa ggagtttgat taaaaatgtc tttagtaaaa tattgcagat
     4861 gtgatgatag attaatacat ggtcaagtga tatataaatg ggttaagcat ctaggtgtaa
     4921 aaaagatagt agtagtagat gatgaaacaa ccaatgatgt tattgctaaa ggtttgataa
     4981 aaatggcagc accaaagaat attgatttat caatattaac tgtaagtgaa tcaaggagat
     5041 atttttataa taatcaagct gatgataacg tttttgtatt aattaaaaat ttagatactg
     5101 caaatagaat gatagaagaa gggattaata tcaaaaaact tattgttgga agaataccta
     5161 caggaatagg aaaaaagaaa atatctcaaa atgtatacat taataaaaaa gagtttcttt
     5221 taatagatga atttattaaa aagaatatta atgtatcaat tcaaatggta cctgatgaag
     5281 aagaagtaga attaaaccaa aatattaatc gctataaagg agagtttatt tagcaatgaa
     5341 taaatataag gtaattatac tgtgccatgg aacttgggga aaagtcttag tagaagaaac
     5401 aaataaaaac tttggattgt caaatcaata tgaagtttta tcactaagtt ctgaaaaaga
     5461 tgtttctgta tttatgaaag aggttgaaga agtagtagat aaagaagatg tgaaaattat
     5521 aatatcagat ttatatggag gatctacatc aagtgttgca atagctgttg ctataagaag
     5581 aggaatagat gcaataaatg gacttagctt acagacaatt ttaatcgtag atgaagaatt
     5641 aagcaaagaa gataaattac atacattacc agaaagaatc gtcaaaaaaa ataataacct
     5701 ttgtgtggat ttaattaaag aatttaaaaa aatataaatt atgaggtgaa tataatggca
     5761 aaaataacat tagtaagagt agaccacaga ttaattcatg ggcaagttat aacaaaatgg
     5821 gtaaaaatcg ctcaagctca aaaaataata atagttgatg acttcttagg tcaagatgaa
     5881 tttatggctg acatatataa aatggcagca ccatcaggag tagaagtagt tattttaaca
     5941 gcagaagatg cgggacaagc attccaaaac aacactttag gagataaaaa tatatttatt
     6001 ctatttaaaa atgttgatat ggcaaataag gcttataaag ctggacttaa atatgaaaag
     6061 attcaattag gaggtattcc aaatgaagca ggaaagaaaa tggtgtttac agctgtttca
     6121 ttaggaaatg aggatgtaga acaacttaat gaacttaatg aaaatggggt tgaaatagtc
     6181 ctacaagtta taccagagga atcatctatg acatatgaaa atgcgttaaa gaaatttaaa
     6241 taaaaaatat aaattaggag gaattataaa tggaatctgt tttgatgttg gcaattgtaa
     6301 caggattatg gtattggttt gcagcaggtc ttgcagggta tacccttttc tcaacactaa
     6361 agtctccttt atttataggt tttagccttg gattactttg gggtgatgta acaactggta
     6421 tgattgttgg tgcaagtata gaaatggttt atctaggaat ggtcgcagca gggggaaata
     6481 ttccatcaga taaatgtcta gctgctctta ttgcaatacc agtagcactt caaactggtg
     6541 ttaatgcaga agttgcagta tctattgcgg tacctttagg tgttatagga gtattagtta
     6601 ataacttaag aagaactggt aatgctgtat tggttcataa ggcagataag tatgctgaag
     6661 aaggtaatac aaaaggcatc tggagatgtg caacacttta ttctttaata tttgggtttg
     6721 ttttaagatt tccaatagtt tttgtatgta acttttttgg agcagattta gttcaatcat
     6781 tattagatgt tataccacaa tggttaatga atggattaac agtaatgggc ggtatattac
     6841 ctgcattagg ttttgcaaca acaatattta ctataggtaa aaataaattc ttaccaatgt
     6901 ttattatagg attttttatg gttcaatatt ttgaaatatc aattactgca gctgcaatat
     6961 ttggtgtttg tatagctctt ttaattacct ttatgaaaga agacaaaagg gtaggtgaag
     7021 tataatgcaa gaaataaaaa ataaagaagt taaaaatgga caaggtccaa ctgaagttaa
     7081 taagacaaga gtactcacaa agaaagatgt aacaaaaaca tacctaagat ggtggtggac
     7141 agcagagtta tctaattctt ttgaaagaat gcaagcatta gcagtttgtg caagtttcac
     7201 tccggcttta gaaaagttat ataagaaaaa agaagattta gtagatgcat taaagagaca
     7261 cttacaattt tttaatactc aagctatatg gggaggatta attcatggta cagttttagc
     7321 tatggaagaa gagaaagcta ctgaaggaaa aatcccagga gaagttattt caggtgttaa
     7381 gaatggtctt atgggacctt tggctggaat tggagatact ttagattttg gtacatttca
     7441 aacaatattc ttagctttag gtgcttcatt tggagcagaa ggaagtgtta taggtgcatt
     7501 tttcccaata atgtttagta tattactatt ttgcgaaggt tattacttat ttcatttagg
     7561 atattcttta ggtagagatt caattaagaa aattctatca ggtggtattg tcaataagat
     7621 aattgatggt gcttcaattc taggaatgtt tatgatggga gcattatctg caactacagt
     7681 taagctttca actccgctat catttgatat tggtggtaaa gcaattgttg ttcaagatac
     7741 attaaatatg attgctccag gtttattacc acttggtgtt gtattcttcg tatattgggg
     7801 aatgaaatac aagaagtgga caataactaa gttattagta attttagttg tattagcatt
     7861 ggtaggatca ttcattggaa tattctaatt cacagtgatt aaaatataga atttaatttt
     7921 aggaggagaa agaaatgtca gaaaaaatgt atacagaaaa ggaatattta gaaggaatta
     7981 gaggagcaac aggagaaaga gcagtatggt tctatcttct tatgaaagaa gctgaaaaat
     8041 taggagctaa tccagatgat atatgtaaag aagcaatata tggatttggt aaaatgagag
     8101 gtcaaaaata taacgtagca gatactccag gaaaaatggc agaaatgtta tataacagta
     8161 aaggacaaaa agtgtttgaa atggaattag tagaaaatac agatgagaat ggcgttttaa
     8221 aattccatca ctgtccatta gatgctgctt ggaaagaata tggattaact aaagaagaaa
     8281 gaaaagaaat ttgtagatta gcttgttatg gggattatgg aagagttgac tgtgcacaag
     8341 gtgttaaatt agattttgct caaaaatgtg ctcatgatga tgaagtttgt gaattagtat
     8401 ttacaaaaaa ataattttta atgctaaaag cctgttcttt aaggacaggc tttaaaaaga
     8461 tagaaagtag gttgatttat ggatataagc agaagtgtag ataatagttt aaatagaacc
     8521 atagaatttc taaaagaatt gataaaaatt gattcacaac aaggtgaacc tatttcacaa
     8581 tgtccttttg gtataggacc taaaaaatct ttagataaaa ctttagatta ctgtgctagt
     8641 ttaggtttta gtgttaaaaa tattgataat tatattggat atgcagaaat tggagaggga
     8701 gaggaattaa tagggattcc aatgcattta gatatagttc caccaggaga ggggtggagt
     8761 gtagacccat tttcgggagc agtaattgac aatattattt atggaagagg tgtcatagat
     8821 aataagggtg ctgtatctat gcttatacat gtattgaaaa acatagagga tatgtatcct
     8881 acaattaata aaagaataag attaattttt ggtacaaatg aggagacaga tatgaaatgt
     8941 atcaaatatt acttagataa aggtgaagaa attccaagta tgggatttac tccagatgct
     9001 atgtatccag tggttaatgg agaaaaagga agggttcata taaggataga aaaagaaatt
     9061 aaaattgaca aaagtaaacc ttacataata gtaaggggag gaactaaaga aaatgttgtt
     9121 ccatctcatt gtactgcaaa aattattaat ggaattattt cagagttaac tactaaagga
     9181 gtagctgtac atgcaagtaa tcctgaaaag ggagaaaatg ctatatctaa aatggtaata
     9241 aagatagttg aggataatat ggattttcag catagagaag atatagaatt agtttcaaaa
     9301 tacctttgta gtgattatta tggagatgca ttggggatta atcaatatga tgaggtattc
     9361 aaaaacacta ccttaaattt aggaatatta aaagtaaatg aggaaaaaat cgtatgtgag
     9421 ttagatataa ggtatggtaa aaatatagtt ttaaataaca taatagatag attcaaaaag
     9481 gttttttgta atggttggaa aatagaggtt attgctcata aagacttaca ttatgtggat
     9541 gagagtaatt tagtacttaa aaaattatta gaagcctatg aagaagtaac agatgaaaat
     9601 ggatatacaa ttgctatggg tggtggcaca tatgcaagtt ggtttaaaga tatggtggcg
     9661 tttggaccta agttcttagc gtataaaact ggtggtcatg gagtagatga aagagtacca
     9721 ataaatcata tacgaaagaa tatggagata tatactttgg ctttaataaa actattagaa
     9781 ttgtaaaaga agaagagact ttatgtgcaa atttacagat atcttaaaaa gagagataaa
     9841 acgagttcaa ctttatttaa atgttcaaca ccatcaaatg gggctgtctc aaaatagaga
     9901 taagcctctt gcttattatt gaaatgatga aaatatattt tacttcatac aaaaaagagt
     9961 gccttatgaa gtaaaaagtt aattttgaga caccctcatt tgatgatgtt gaagagaaaa
    10021 taagtatgaa attattaaaa aaagatgatt ttataaaagt taaggttgaa aataaaagtt
    10081 aattgaatgg aattagataa atggagaagg ctgtatacta tctaataaaa taacaaaaga
    10141 gtgttataaa actggttata tgattagaga aaagtctatt gatacttatc cagatagtgg
    10201 acggggattt atgacttggg atgaaaatgg agaataataa aaattatagt ttatacaatt
    10261 taataagata tatgtacaag cagttaatct aaatgattga ctgcttttct tttatagatt
    10321 tttatataat agacaattac taatacatga tagttgcctg ttataattag aggaatagat
    10381 acgaataata actttataaa agaattaaat ggaaaattga agagttatat tcaggatttt
    10441 aaaaagaata tgaaatgaga aatgaaaata aggtgtttat attaaaagag gttttacaca
    10501 aaatacttaa aaacgtgata aataaaaact gtatttagat aaattaacta ctagttttat
    10561 atataatatg gattttgttt acaaagttta catatttcac aaaatatttt taaaatatat
    10621 ttaaaaatat attttatata cttgttcgtt tgtttctctg tggttgattt tttcgtcaaa
    10681 agtcaacttc aaatcgcttg ttagctttac atgtttaagg atataattat acataaggag
    10741 ggattgacat gaatgaatta aacatcgcaa aaacgctgat tttaaagcgt aaagaaaaag
    10801 gaattacaca agatgaactt gcaaattata taggcgtttc taaagcttct gtatctaaat
    10861 gggaaactgg acaaagctat cctgacataa cctttttacc gcaactcgcg acatatttca
    10921 acattaccgt tgatgagtta atatgttatg aacctcaaat gatgaaggaa gatattaata
    10981 aactgtataa taaactgtgc aaagacttta cggttaaacc gtttgatgaa gtcatggatg
    11041 aaataagaga aatcataaaa aaatattatt catgttttcc tttgattttt cggatgggtc
    11101 ttttaatagt taatcactat gatattgtag atgaaaaaaa gcgtgaacta ttaattagtg
    11161 aagcattaga aatatttatt cgtatacagg aaacttgtaa tgacatagat atttgccgtc
    11221 aagcaaaaag tatggaggca acttgttata tattgttaaa tcaacccata caagtgattg
    11281 atttattgca aaacagcaat tttcccatga taaatgaatc tatacttctt gcacaggggc
    11341 aaatgatgaa tggtcaaatg gatgaagcaa gagaaacatt tcaacttggt gcatatcaga
    11401 accttatatc attagtccaa aatctagtgg gtattttgca aaatgcagat aaattacaaa
    11461 tgaaggaaat agaaagacgt attctagcaa tttcagatat atttgagctt gatacattat
    11521 ctcctgctat tatgctttct tcatatttaa cacagacaca aattaattta atacatgggg
    11581 ataatgaagg agctattaaa tcattacgaa aatatgtaga tttagcaaca cgtgatatat
    11641 acccaattat aatacatggg gatgactttt ttaataaact tgacagatgg atttctgaaa
    11701 ttggaacagg tattacacgt gatgatacaa tcgtaaaagc aggtattgtt gctgctatta
    11761 aaaataatcc aatgttttct ttattaagtg aaaacaaaga atacaaattt cttatagaaa
    11821 aattatcttt attggaggaa taagattatg gaaaatttga tggaatattt accacttttg
    11881 attcctgtta ttattttaga tttaatactt ataattactg cacttgttca tgtattgaga
    11941 catccaaatt ataaaattgg aaataaggca atatggatta ttgtagtact gtttattagt
    12001 ctaataggac caatcttgta ttttacaata ggaagaggtg aagaatgatg aatattgtct
    12061 caataaatgg attatcaaaa ggttttggta atcgaaagat aatagataat ctaaatttta
    12121 ctgtaccaga agggtcagtc tttgggtttg taggtaagaa tggtgcaggt aagactacaa
    12181 caatgaaaat ggtacttggg ttacttgaac cagatagtgg aactatagat gtttgtggtg
    12241 agaaagtgac atatggaaga acaagttcta atcgtcatgt aggttatctg cctgacgttc
    12301 cagagtttta caactatatg agaccacttg aatatctttc tctttgtggt gaaattacgg
    12361 ggctttcaaa aaaagaaata aagataagga gtgaagagtt gttatcactt gtggggcttg
    12421 gcaatgaaaa gagacgaata ggtgggtttt ctcgtggaat gaagcaacga cttggtatag
    12481 ctcaagcttt gctttcacgt cccaaattac ttatttgtga tgaaccaaca agtgcacttg
    12541 accctgttgg tcgaaaagaa atattagata ttatgcttaa aatcaaagac tcaacaactg
    12601 taatattttc aacacatata ctatcagatg ttgaaagaat ctgtgaccat gttgctatac
    12661 taaacaaagg aagcattgct cttagcggta cactttcaga aataaaaagt atgcacggaa
    12721 aggatagact tttactggag tttgcaagta ataatgaaat tcaaaagttt aagtctagtg
    12781 gtggcattaa atccttacta aaagattcag aagaaactaa tatggaaatt gttttgcatg
    12841 gtaaagatat aaaagcaata caaaaaacag ttatatctac actcgcagaa atgaatcttt
    12901 gtccagtaaa gatggaacta atagaattgt cacttgaaaa tttgtttttg gaggtagtaa
    12961 agtgagagaa tacatagcat ttacaaaaaa agagtttaag gagaacataa gaaattataa
    13021 attacttagt ttgactattt tatttttagt atttggaata atgagtcctc tttctgcaaa
    13081 atttatgcca gacttgattg ctcattttgc tccaacttta aaagttacta ctgcaccaac
    13141 tgctttagat tcttggacac agttttctgg aaatatttct ggtcttggaa cgagtttaac
    13201 tctaattgtt ttttgcaata ttttatcaaa cgaatattct aaaggaacac tcgttattat
    13261 gttgactaaa gggttatcac gttcatctgt agtattgtct aaattttcta ttgcagtaat
    13321 tattatgaca attggttttt ggttgagctt tttatgtact tatggatata caatgtattt
    13381 ttggccaact gcaaatctta atcatattat attttcagca tttaacttat ggttaattag
    13441 tattatgtat atttccatat taattcttgg gtgtgtacta tttagaccag catttgcaag
    13501 tgtgttactt gtattagcag caactgctat tttgagtttg atttctattc ctaaacagat
    13561 tgcaccttat acgcctaatt tcatattatc aaaaaatata gatttagttt caggtaaagt
    13621 gacacctcca gaatttatta ttccaatcat tgtaacaatt gttatttcga tagtatgtct
    13681 gttattagct gttgttttgt ttaataaaaa agcagtttaa ggatattttt attataaata
    13741 caaatagtgc tgtattgtgg gaaaatgtgt ttagtattgt agaagaatat atttaagtaa
    13801 aaaagaggct gtctcaagat agagaaataa gcctcttttt tattttagtc ctcctcacta
    13861 tactttataa taattaagtt attaccttaa ggaactatct aaaaaaagag atatagatta
    13921 taatctaatg cttatcagtt atttgaggtg tttagtatat agagtctaaa gtagtgaagg
    13981 actaaaataa tattgttttc attaaataaa gataagaatc tttaattgtg gtaaaatata
    14041 ctaaaaaatc attttaaaag tgataaaatt attttaagta aatattttaa aggggtgtag
    14101 atatggaaaa gtcaaaagta tatttttgtg atttatactc aaattcgcaa aataaaaacg
    14161 taccaaacaa tgtaagaaga ttatttgatg aagcaggatt caaagattta atagaaaaga
    14221 atgaccaagt cgcaattaaa cttcactttg gagaaaaggg aaatactaca tatatgagtc
    14281 ctgtggcagt tagacaagtg gttgataagg ttaaagactg cgaaggaaag ccatttttaa
    14341 cagatacaaa tacactgtat acagggagta gaacaaattc tgtagaccat cttacaactg
    14401 ctatagaaaa tggatttgct tatgcagttg taaatgcacc agtaataatt gcagatggat
    14461 tatatagtag aaattatgag aatgtaaaaa tagacaaaaa acattttgaa agtgtaaaaa
    14521 taggtggaga aatttataat tcttctgcaa tgatagtaat gagtcatttt aaaggtcatg
    14581 aagcagcagg ttttggagga gcattaaaaa acttagctat gggatgtgca agtgcagcag
    14641 gaaaacaaat gcaacattct gatgttactc cagtagtaaa ggaaaagaag tgtgtaggtt
    14701 gtggaaagtg tgttaattct tgtcctacaa aagctataag tatagtggat aaaaaagcag
    14761 ttatagattc tgatgtatgt tatggatgtg gagaatgtcc aactgtctgt ccaactagag
    14821 cagtaactat acaatgggaa agtgactcag atgtgtttgt cgaaaagatg gcagaatacg
    14881 cttatggagc agtatcaaat aaaaaagaca aggtagggta tataactttt gttatgaatg
    14941 taactccact ttgtgattgt gtaccttggt caggtagacc aattgcccat gatataggaa
    15001 tattagcatc aacagaccct gtagctattg aacaagcatg ctatgatttg atttgtaagg
    15061 aaatgggtca tgatgttttc aaacatgaac atcctcatgt aaatggaact agaataatag
    15121 actatgcatg tgaaatgggt atgggaagta aagaatatga attaataaaa ttataagaat
    15181 agtagcactt aaatgcatat aattattgta agagaaatct aaaagtatca aaggagtatg
    15241 catttatgaa aatttactat gagaaggaaa acagcaagaa ggctaatgta aacaatattc
    15301 caagtgtatt tgcgtttaat tttctaagaa actttttgac tagcaaagag tatgaggaaa
    15361 ctagaaaaga atattttata aataatctaa caaaaagtca ggttaatcaa gccatgaagg
    15421 atttaaaatg gctatttaga gaatatgaag gcttagaggt tattacaatg gaaagcttgg
    15481 atggagttaa gacaaggata gttttataaa ccagtaagaa ttatattcta ataaaaaata
    15541 ctgctttaat aataatatgt ataatctata tactaatatt attttgaagc agtatttttt
    15601 tgtgtatagt aaacttgtgt ctaaaataaa gttgaccaat aaatgttata tatgcaatac
    15661 tatatataat aagtaaacta cataaaaata ttaagttgac aaataggagg atatatggaa
    15721 aaatacataa taaaattaaa aaataaagta ttgagagaaa aagaaataag ttatgaagaa
    15781 gctcttaatt taataagcct tgatacaaat aataaaaacg attttgatat tctattaaaa
    15841 tctgcaaatg aaataagaga atattttatg ggaagaaaag cagatttatg tacgataatg
    15901 aatgctaaat ctggcaaatg tagtgaagac tgtaaatttt gtgctcaatc atctcattat
    15961 aaaactggtg tagaagaata ttcattatta gattacaatg aaatcttaaa tagagctaaa
    16021 gagatggaga gtaaaggagt gcatagattc tcattggtta caagtggtaa aggtatgtca
    16081 ggaaaggagt ttaataatat tttaaatatc tatgaaggat tgagggaaaa tactaattta
    16141 aaattatgtg catctttagg tattatagat tatgagcaag ctaaaatgtt gaagtcagca
    16201 ggtgtgacta catatcacca caatgttgag acgtgtagag ataattttca taatatatgt
    16261 acaacacaca catataaaga taggataaaa actataaaag atgctaaaaa agctgggcta
    16321 gatgtatgtg taggcggtat aattggaatg aatgagagtg aagaacagag actaaaaatg
    16381 gtttttgaaa tacgagaatt aaatgtaaaa tcatttccaa taaacatttt aaatcctatt
    16441 aagaatacgc caatggaaaa ttatgatgta ttagaaccaa tggaaatact aaaaacaaca
    16501 gcagtattta ggtttataat tcctaatgtg tacataaggt atgctggtgg aaggctatca
    16561 ttaaagggat atgacaaagt tggatttaat gggggagtaa attctgcaat tgttggtgat
    16621 tatttgacaa ctgttggaag tgggattgaa aatgataaaa aaatgattat agagcaagga
    16681 tttgaacttt aataaatact acttaaatta attaatatac ttttagataa ttataaaagt
    16741 atattaattt tttttgcaga ttaatttaaa tattaaaatt gaattataag ttgcaatatt
    16801 ttgaaaaaag ggaaaaatat caaaatttat ataaaatggt tgcaaatggg aaaaggatgt
    16861 gatagtatct aggtaaccgg ttaagtaaaa cggtttccta aattttgggg gtgaacttct
    16921 tgagtataac tataaaagaa attggcgaat tggctggtgt ttctaaaaca actgtgtcaa
    16981 aagtcattaa taataaagat gaaaatataa gtcaggcaac aagagaaaaa attttgaaaa
    17041 taatgaagga aaaaaattat gtaccaaata aattagcaca aagtttagta actaaaaaaa
    17101 ctaatactat agggcttctt ataccagata tacgaaatcc attctttaca gatgtatcaa
    17161 gaggtgtaga agacaaagct aatgaagaag gctacaatat aattttatgt aatacagatg
    17221 aagatgctaa aaaagaatat gaaggaataa gaacactatc agagaggatg atagatggaa
    17281 ttatatttgc agcatcttca aatacaaact ggaaagaagc aaattataaa gatataaaaa
    17341 taccaactgt cttgattgat aagaagataa gtatgaacaa agaaacctta aaaggaattg
    17401 ttaaaataaa taactttgaa ggggcctata tagctacaaa acatttatta gatattggaa
    17461 ataagaaaat aatataccta agtggtccac ttcaaaatga aatagcagta gatagattag
    17521 aaggatataa aaaggctcta atcgagtgta atttaagcta caattctgct tatgtatttg
    17581 aaggaaaata taagattgaa tggggacaag aatttataaa aaatttagaa aagatagatt
    17641 ttgatgcaat attttgtgca aatgatttga ttgcaatagg tgtcataaga ggtcttaaag
    17701 aaagagggtt aagtatacca aatgatgtaa gtgtcgtggg atttgatgat attcaaacat
    17761 caagtctaat aagcccttct cttaccacag taaaacagcc gtcttatgat ataggatata
    17821 aagccagtga aatattgata aattgtttaa gaggagataa aaaagaatca tttgatgaat
    17881 tgattttcaa accagaatta gtcataagag attcaacaaa agaaagtgaa taacagcacg
    17941 agagacataa atagatatgt aaaggagtaa tgtaatggga aacatagttg tcataggaag
    18001 tgtaaacatg gacatggtat gttctgtaga taaaagacca gaaaaaggag aaacagtatt
    18061 aggtaatagt ttttttacat cacctggagg gaaaggggct aatcaagcta tctcagcttc
    18121 taaactagga gcaaatgtaa aaatgatatc atgcataggg gaagatggct taggagagga
    18181 gttaataaga aattttagaa cgaataaagt tgattatagt ttagtatcca gaaataatca
    18241 caaaagttct ggtgttgctg ttataacatt atgtgaaaat gataatagta ttgttgttgt
    18301 accagggacg aatgagctag tagatataga attaattaaa aagaatgaag aagagataaa
    18361 gaatgcagat atagtattgc tacaattaga gattccatta aaaacaataa attatgtagt
    18421 gaatttctgt tttgaaaata ggattaaggt tttattaaat ccagcaccag cagtaaaact
    18481 aaatgaagat ataatagaaa aagtaactta cttaacacca aatgaacatg aatataagat
    18541 agtttttgac acaaatgaag ggatagaaga agtattaaaa aaatatccaa ataaacttgt
    18601 aataacagaa ggaaaaaatg gagctagatt ttatgatggt gaggaaatca agcatgtatc
    18661 ttgtataagt gttgatgttc aagataccac aggagcagga gatacattta atggagcatt
    18721 ggcagtggct ataacagaag ggaaaaaatt atatacagca gtagaatatg cagtagtagt
    18781 atcaggtctt tctgtaacta aactaggtgc acaatctggt atgccttata aagaagatgt
    18841 tgaaaaatat ttaaataata aataaaaatc taatttgttc aaatttaaaa ctattaaaaa
    18901 tggaggttaa ttatgagagt gagaaaaatt ttatctttag gaattgctgg aatactagca
    18961 ataggaatgt taacagggtg ttcaatggaa ggaccaagta aatcagataa taaaggtggt
    19021 tcagacaaga aagatttaac tattggagta tctacaataa ctcttcaaca tcaatttttt
    19081 atagatattg atgagggaat aaaagaaaaa gctaaggaat taggtgtgaa agttatagta
    19141 aatgacccag accaagatgt agctaagcaa acatcagcaa tagaagattt tatacaacaa
    19201 aatgtagatg gaatgatagt acttggaact gataattcgg ctatagtacc agcagtagaa
    19261 ggagcatttg aaaaaatgcc agtagttaca gtagatgctg tattaaatac tgaaaatatt
    19321 acaagttatg taggaacagt tagttatgat gctggtaaaa aattagggga atacactaaa
    19381 aaatacatag atgaaaagtt aggtggaaag tcagaaatag caatagtgac agatttaaaa
    19441 tctcaaatac aaatgcagag aatagatgga tttaaagatg cgttaaaagg ttcagcaaat
    19501 gttaagatat taaattcaca accaggatat gacagagaag aatctcttaa tacagtagaa
    19561 aacttaattc aatctaatcc agatgtagat ataatatatg caacagctga aaatagtgta
    19621 ctaggagcta aagctgcact tgaatctgca aaaaataagg atgttaagat tgtaggattt
    19681 gacttaactg aagaagcatc aagtggaata acagatggaa ctattcttgc tatgattcaa
    19741 caacaaccta aagagatggg acgtttagct gtagaagcag tagtaaaagc tataaaaggg
    19801 gaaaaggtag aaaagaatat accagtacca gctttacttt atgataagga aaatataaaa
    19861 gactttaaga attagtaaaa taaaatgaga ttatttgaaa gaaatcctat ttaaaaagga
    19921 gtgtcattat gagtaatata attctgaagt taagtaatat tgctaaagaa tttcctggtg
    19981 tcagagcatt agataatgtt aattttgagt tatttcatgg cgaagttcat gcactactgg
    20041 gtgaaaatgg tgctggtaaa tcaacaatga taaagatttt aactggtgca cattcgaaaa
    20101 cttctggaaa atttattttt gaaggcaaag aaatagagaa tatatcccca gatatctcta
    20161 aaaagatagg tataaatgcc atatatcaag aactaacagt ttttgacgaa ttaacagtag
    20221 cacaaaatat ttttatggga aaagaaataa atggcaaagt cttaaccaat gacaaaaaaa
    20281 tgaatgaaga ggctaaaaag attttcgata atatgggaat agatataaat ccaaatagtt
    20341 tagtcaaaga gcttagtata gctcaaaaac aaatggtaga aatagcaaga gttttatcat
    20401 cagaaactaa agtattaata atggatgaac ctacttcttc aataagtaaa aaagagactg
    20461 aaatactttt tagacttata aatgatttaa aagagagtgg agttagtata atatatatat
    20521 cccataggat ggaagaactc tttgagattt gtgacagaat aactataatg cgagatggga
    20581 aaacgatttc gactttgaat accaaagatg tatcgtctga ggaagaatta gttaatttaa
    20641 tgatagatag aaagctagac caatttttcc caaaaagaaa agtagaaata aaagaagaaa
    20701 ttatgcgagt ggaaaatcta actaagaaca atgtttttaa tgatattagc tttaatataa
    20761 gaaaaggtga aatattggga ataggtggac tagttggaag taagagaagt gaaatagtag
    20821 aagctatatt tggacttaga acatatgatt ctgggaaaat atatttaaac aatgaagaag
    20881 taaagtttaa aactccatca gatgcaatag aaaatggact gggattaata acagaagata
    20941 gaaaaggtac tggattgttt ttacaaatga gtgtcaaaga aaacacaact atggctgggt
    21001 taaaaaagat atctaagttt aaatcaatta tagatagaaa aaaggaaaaa gagattttag
    21061 aaaaatacat agaagcttta aagataaaaa caccacatat gaatcaagtt atacaaagtt
    21121 taagtggtgg aaaccaacaa aaagctataa tagcaagatg gcttttatta caaccagata
    21181 tattgattat ggatgaacca accagaggta tagatgtaaa tgctaaggca gagatataca
    21241 atctaatggg agatttagtg gagagtggtg taagtataat aatgatatct tctgaaatac
    21301 cagaattaat atcaatgagt gacagaataa tggttatgag agaaggtcat ataagtggat
    21361 ttttagaagg tgaagaaatg gttgaaaata atgtattaaa attggctttc ggaggtaaaa
    21421 ttaatgagtt caataactaa gcataaagaa gaaaaatctt ctccattatt gacaaaatta
    21481 acaagtgtat ttagagacca agggagtgca gctgtaggac ttgtaataat ttttataata
    21541 atgagtgtag cttcatctaa ctttttaact ttagataatt taattaatgt tggaagacaa
    21601 atatcaataa atgcaatact tgcagtaggt atgacatttg taataattac aggaggaata
    21661 gatttaagtg taggagcagt aattgcttta gtaggtacat tttgggctac aacagtagtg
    21721 aattataatg cacctatatg ggtaggtatg atacttgcat tagcaatagg gacaatatta
    21781 ggagtcataa aaggtgcaat tatttcaaca caaaaactac ctccattcat tgtaacttta
    21841 gccatgttaa cgataataag tggggcaagc tttgtattta caggaggaag acctatatca
    21901 gtaaatacag atgcatttaa gatgctcggt agaggatata ttggaccaat accaatacca
    21961 gttataatta tgattatagt tgtaatagca ggacattttc tattaaaaag aactaatttt
    22021 ggacgtcatg tacatgcagt aggtggaaat gaagaggccg ctagattatg tggagtaaaa
    22081 gtaaataaag ttatagtaaa agtatacgca ctagctggac tactaacagc attagctggg
    22141 ataatactat catcacgttt ggcatcaggt tcaccaactg ttggagatgg agcagaattg
    22201 gatgctatag cagccgttgt gcttggtggt actaatatga tgggtggttc tggttctata
    22261 gtaggtacat gtataggtgt cggaataata ggaatattag gaaatggatt aaacttatta
    22321 agtgtatctt catataatca aatgattata aaaggtttgg taatgttatt tgctatatgg
    22381 ataaataata taaaattaaa aaaatcagct aaatctaaat agtaattaaa ttttagctta
    22441 taaactataa aaattattaa gtttttgtat atatttttat actttaattt gcatacatct
    22501 ttatacattg aatgggaata tgctaagtga aaaagtttac tatggcttaa atagatgaga
    22561 ttagacttga aattttaaat gtaaaaataa atcttaggag gaaatatgaa aaaaattctc
    22621 ttagatacat taaatagtaa aaaacaagaa tacatagatt atttaaaaga acttgtaagt
    22681 ataaagactg aagatgttgg tcatggaata ctaggtggat ttgaaaaaga aggacaggaa
    22741 tatattgaaa aacttgcaaa ttacataggt tttagtgtag atagacaaga aatgagcgaa
    22801 gaattaatta aaaaagcaaa aaatatatat aaagaaggaa atctaggtca caattatcaa
    22861 gatagatata atttaatttg taagtatagt gatgatttac ctggtaagac aattgtattt
    22921 aatggtcatg tagacactat gccaccaggt gatataagta agtggaaata taatccatat
    22981 cgtgctacag aagataatgg aaaactttat ggtcttggaa ctgctgatat gaaatctgga
    23041 cttatagcat caatattagc tgtaaagctt ataaaagata gtggtctaaa tgtacctggt
    23101 aatgtaaaaa taatgtcagt agtagatgaa gaaggtggcg gaaatggtac cataaatgca
    23161 gttatgaatg gtattggtgg agattgttgc ataatttgtg aaccatcaga acaaaactta
    23221 atagttgcac atatgggatt tgtattcttt gaagttgagg ttaaaggtgt gtctcttcac
    23281 tgtggtagta agtgggaggg tgtaaatgca attgagaagg ctatgttgtt gcttcaagat
    23341 ataaaagagt tggaacataa ctggcttatg atatataagc atccactatt accttcacct
    23401 acaataaatt taggtgtaat aaatggtgga acagcaggtt ctactgtgcc agataagtgt
    23461 gtatttaatt tatgtgtaca cttcttgcca aatataatga gttatgaaca agttgtaaat
    23521 gatgtaacaa atgtcataat gacaagggct aatggagatt tatggcttaa agataataaa
    23581 ccaaatataa acatatatca atcagggtta ggttttcaga tggacaagga ttctgatttt
    23641 gtagtgaatg cacataaaat actagaagaa actttaggaa aaaaattaga gataaaaggt
    23701 tcaacagctg gcaatgatgc gagattaatg aaaaatttag ctgaaatacc aacacttata
    23761 ttagggccag gttcaataga acaatgtcat tcaattgatg aatatgttga aattaaggag
    23821 tatttagata gtatacttat gtatgcaagt ctaatattaa acttataaaa gtaggaggaa
    23881 tatataaatg aaaaaagtat taatagtagg ggaatcttgg gtaaaaaata taactcatat
    23941 aaaaggattt gatacgtttg ttacaactca ttatgaagaa gctgtaaagt ggttgaaaga
    24001 agcaatagaa tctggaggat atgagacagt tcatatgcct gcacatgtag cagcagatag
    24061 ttttccgtat aaattagaag agttaaatga gtatgactgt ataatattat ctgatatagg
    24121 ttctaatacg ttcttattat ctaatagtac ttttatagat tgcaatagta atccagatag
    24181 acttgaacta atcaaagagt atgtaaataa tggtggggcg ttaatcatgg taggtggata
    24241 tatgtcattt acaggaatag atgcaaaagc tagatttgga gaaactgcta tcaaagatgt
    24301 attaccaata acaatgatag ataaagatga tagagttgaa aaaccagcag gaataattcc
    24361 agaagttatt gactctgaac atccagtatt aaaaggtata ccaacagaat ggccaaagtt
    24421 tttaggatat aacaaaacag tagctagaga taattgtcct gttttagcaa ctattggagg
    24481 agacccattt gtagctgttg gcgagtttgg aaaaggaaaa tctgctatct ttagttctga
    24541 ctgtgcacct cactggggtc caaaagaatt tactgattgg aaatactata ataaattatg
    24601 ggttaatatg cttgattggt taacatgcta aaaattttat aaaacttgaa aacctcttac
    24661 ttgataaaat gaaacttaca agtcaagagg ttttattgta taaaatggtt gtatggtaga
    24721 aaatattttt aaatcagtta aaattagtca ttttggctga taatcgataa gttattagaa
    24781 acagggaggt ttatataatt aatatggata atttaaataa aaagtttttg atggaatata
    24841 tagatgagat acagggagaa ttaagagata tatcagataa gatatggaaa aatccagaac
    24901 ttcagtataa agaatactat gcttcaaatt tacaaaaaga atgtttaaaa aaacatggtt
    24961 ttagtataga gggattagaa ggtatggata cagcatttgt ggctagttat ggagaaggta
    25021 gaccagttat agcagttttg ggagaatatg atgctttaga tggtttgtct caaaaagtat
    25081 ccactactaa agaacctatt gtagatggtg gtgcaggtca tggatgtgga cataacttac
    25141 ttggtacagg ttcaatagga gctgtaattg cagtaaagga attaatcaaa ctaaaaaagc
    25201 tgaaagggac tataaaatac tatggatgtc cagcagaaga agatttatct ggaaaagtat
    25261 tgatgataaa aaaaggtttt tttgatggaa ttgattgtgc ttttagttgg catccatttg
    25321 atataaatac tccgataaga atcccaacac ttgctaatta ctctgtgaaa tttagatata
    25381 atgggattag tgctcatgca gcacaagctc cttataacgg aagaagtgca cttgatgcag
    25441 tagaacttat gaatataggt tgtaattatt tgagagaaca tatatttgat aattgtagag
    25501 tacactatgt aactactaat ggtggaaaaa tgccaaatat agttcctgat tttgcagaag
    25561 tgtggtatta cataagagga gttaaaatgg agcatgtaag agatgtattt ggtaggattg
    25621 ttgatatagc aaaaggagca gcattaatga ctggtactat tatggaatat gacattataa
    25681 gtggagtata tgactatatt ccaaatacaa tattaacaga tattctatca caaaatatga
    25741 aattagtagg tgtgcaaaac tataatgaag atgactacta ttttgcagat aaattagctg
    25801 agacagtgtc tatagataaa agaagtagtg tttctagtgt attaagtgga aataaggata
    25861 ttactaagat gaatttacat gatgaggtta cagatgatac atttactcat aataactgta
    25921 tatcattatc attggatatt ggagatgtta gctacataat tcctacagca caatgttctt
    25981 gttcagtttg gcctattggt atttctgccc atacatggca atcttgtgcc agtgcaggtt
    26041 ctgatatggg atttaaggca atgttattgg catctaaatc tatatcatgt tcaataaatg
    26101 atgtaatgct tgatgaattg gttataaata aagcaaaaaa agaattgaag gatactgtag
    26161 gtagttttga atatactcca attatttgaa gagtaattta atacaagtaa gattgaattg
    26221 tatgaattag gatgaatata taaattaata ttatttttaa cttaactttc taattatttt
    26281 caatctaaga tacaataatt agaatatatt tttaaagttt cctatttaag gaaaataatt
    26341 tgattttatg tttgataaaa ggacttataa tttgtaagcc cttttattat atttattttt
    26401 tgtttataat taattttatt ttttaggttt agttaggtta tagattaccc tgaaaaataa
    26461 catttaactt attattaaaa acatgtaaga atagtttata aatattttat tttcgatgtt
    26521 gtttattata tccattttat cgatggatga ggaatggctc tgccttccct agttacagat
    26581 gtagtaggga aaccaattgc acaggcatca aatccatatt cacctgttgg tactcctaaa
    26641 atatcacaaa aatctttatt atcgctcaat cttcctatta cactaacaag ttcaaaacct
    26701 aatcctaaag cagttgattt aagccacata ttctgcatca catgagataa tgacttttgt
    26761 tctataggtg gtattccacg acgttctgcc acaataataa gataaggtgc tgttcctata
    26821 ccaagaaccc ctttttcaac ttgcattttt aaggaagtaa tgaaggattg aagggtaatg
    26881 ttgttctttg ccttcttctc attgactgat atttgagttt taataacatc aacaagaatg
    26941 gtttttattt tattcatttg taaactgtta tttgaaataa caaagaaatg tctgaaatct
    27001 gtttgttttg ctactgaaag tattgcataa ggtgcaagtc ttccagtttc aattatttct
    27061 tcaatcagcc cttttgaagg tacttctttt gtaaaacttc ttatggatct tctagttctt
    27121 aatagcatat ccaaaacttc attaacattg tttttatcta aattgttcat ttttatcctc
    27181 cactaatagt attcttaaga tgttctataa tgcatccata taaaggcgaa cttttcggtc
    27241 atattaaaca tttccttcaa attaagtcgc tatttctatg aacacaatgt tgattaataa
    27301 tctatatgta tattataata tttatattgc attatgcaat aaacaataat atttaaactg
    27361 ttaagtaata aacatttact ataaaattgt taattaaaat taaaaaaatt tatatggaat
    27421 gaggaaataa ttcatgaaaa aagtatctat tgatagaaga actatacgta ctaaaaaaat
    27481 gattaggtct gcattagcag agttaataga tgagaaagga tttaacaata tatcagttac
    27541 tgatttaact caaagggcag atataaatag aggaaccttc tatctgcatt atgttgataa
    27601 gtatgacttg ttagagagga ttgaaaatga aataatacag gaaattgaag aggagaccaa
    27661 acatcttgat tcatccaaca tgatggagat agatacctca agtgaacctc ttccatttat
    27721 ggtaaagctt tttgaatatt ttagaaaaaa ttcagtaatt attaaatcta tcttgggtcc
    27781 caaaggtgac cctacttttg aaagaaaaat aaaaaaattt attgaaacca atttgtttga
    27841 gaaacaaaaa ctaataaatt ttaacataga tgaggcaata atttcagaag aatattttat
    27901 acaatatata ctttcagcag acttaggtgt aattcaatat tggcttgaaa aaaatatgaa
    27961 agagtcccct gaagaaatgg cactgatact tgctagaatg tcgttactcg gtccgttaag
    28021 agcagtggga attcgtaaag attcataaaa atagttttat atatattaga ctttgaaaat
    28081 atatgtttaa aaaccatttt ttactactac tgtttataaa ttaggggaga tatcttaaaa
    28141 tattagtaaa aggagtgcta agtgagtgta ataactatga gataagaggt ttagttgata
    28201 tagtcaaaac ttcaaaagaa tcaattagaa aagttaaaat attgcaatta aatttaaagg
    28261 agtaatatat gaaaaatgaa aatataagtt atttggcgtt aggattatgt tttggtgttg
    28321 ttttgggttc attatttaaa aacttagcta ttggtttatc ctttggatta gttattggag
    28381 tagtattaga cagtaagaaa aataaataaa acttcaatag taacatataa caattatact
    28441 atttttgtat aaaatcattg gaaatcaaca atagaaaata tttgttattt aaaaactaaa
    28501 aatacagttt aaacgaccta aaaatatatt atataattat tataacaaga taagtgagag
    28561 taaggttatg ataatagagt aatatttttc aattattact ctatttatat ttatttagtt
    28621 atactatagt ttatattgtt attttatttt catatgcagt atagggaatg gattaccttg
    28681 ttcatcgaac tcagattttt taaagacttt aaatcccata tgtttataaa agcctaatgc
    28741 ttgttgattt tgctcattca catctacata atttacattt aatacttcta ttgcatattc
    28801 tacaagtctt tttccaattc catttcctat actataatta cttacaaata acatttcaat
    28861 tttaaaatca tgtattccca taaaagcttt tataatacct ttttttgtct cttacacata
    28921 aaaaattact aacatattta gcacattctt taacttgagg ctttattgat attatatttt
    28981 cttcacttaa aaagtcatgt gttgctctta ctgatgattc ccgtgtatct agtatttctt
    29041 tcatatcttt attgttaata atatttaaat tttcaatttt tatcatttaa taattcctct
    29101 taagtaagta tgttacttaa tattatatgt taaatatgat ttaaaaaggt tataagaata
    29161 tttttgtatt aaatataatc aaataaatat atttatttgt cataaattaa atgtccacta
    29221 aaatagaaaa aataagaaga aataggtaat aaatgatagc ttatagcaaa ataaagatgt
    29281 aagtataaca atagatgaga ttggaattaa gtcactatac ctaacagaac attcttaggc
    29341 gaatatagaa gacttaaaaa agaaaagaga agtagacaag aatttattaa tgattacata
    29401 taaaataaat gaattataat tttattaatg atataataat aattaacaaa aaataaaaga
    29461 ggaacgagtt aatgtttgat ggcatacact cattttctaa ccaataaaac aatagattca
    29521 attaaggtta ctaaagtcta atcaacacat aaacatatag gataaataca tctttttaat
    29581 atattaatta tgttagactt acaaaaaatg taaatacata gcttgttaaa tcttgattga
    29641 accttaagta ataagggata aaaaatgact tgttcaaagg caaagaatat actattaaat
    29701 gatataagta acttagagat aatatgtagt aagtcaaaag aactatatag catcagtaag
    29761 taaaaagcgt aaaaacttac ataatgcact ataaaataaa tgagttagaa aataaatata
    29821 atttatataa taaagtagta caaaaaggag tatttatgtt tggatatgtt aaaataaaca
    29881 aaatggattt aacatttaga gaatatgatt attacaaagc ttactattgt ggactatgta
    29941 aatacttaaa aagaaatcat ggagaaatct ctaggttttc tttgaattat gatataacat
    30001 ttttaattgt tttattaaca gcagtatata acccagagtc tataagtaca gaggaagtgt
    30061 gtatagtaaa tccatttaaa aagaaaaagg taattacaaa tgatattaca gaatatgcag
    30121 caagtatgaa tattctttta acgtattata aattggaaga taatttaatg gatgataaac
    30181 gcataaaaga taaattggca tattatatat ataaaaacaa attaaaatta gcatatgaaa
    30241 agtatcctga aaaagcagag tatataaaac aacaactaaa tgaattaaat aagttagaaa
    30301 aagataaaaa tataaatata gatgaagtat ctagtatatt tggaaatata atgggtgaag
    30361 tatttgtcta taaaaaagat gaaaatgaga gaaacttaag aatgataggt tttaatatag
    30421 gtaagtatat atatctacta gatgcctatg aagatttaga tgaagatttt aagaaaggaa
    30481 gatataatcc atttatagag tatattgata aaaatgatga gttaaaagaa aaagtaaaaa
    30541 aaataatagt aacatcatta ggatttttag ctaggggaat tgataatcta aatctaaata
    30601 aaaatgttgg aataatagaa aatataattt attctggtgt ttatttaaga tatattaata
    30661 tattagaaag tagaggtgga aagaatgtac agtaatactt ataataatga aaattttatg
    30721 agagcaagag cattcataga aaatagtgaa tttaaaaaag catatgattt tttaaaaact
    30781 ttgactgaca aatgtgcaga gtggtattat ttaactggct tttctgcaat gaacatagga
    30841 tattatgaag aaggtgaaga cttcttaaaa agagcaaaat ttatggagcc tgaaaatagt
    30901 gaatatagtg atgcacttag aagttataca caatatagaa atgattatag caatagggct
    30961 gacaattata atagaagaag acgtaatgat ttagatggat gttgttgctg ttgctgtgat
    31021 gattgctgtt gttgtctagg tgacgattgt tgtgaaaatt gtgctaagct ttggtgttta
    31081 gattcatgtt gtgaatgttt tggtggagat ttaataactt gttgttagga tgataaatat
    31141 gagtataaaa gttgcttatg gaggagtttt attagcatta aatgtgatat tgttgactct
    31201 tacaaatatt attcctgtaa atacattgtt tattatgggg ttagcatcac ttttagtatc
    31261 aattgtaata atggaatggg gctttaagag tggaatcgct ttttatatag gttctatagt
    31321 tttaggattt atagtgatgg caagtaagtc tcaatggatt gtatattcac ttacctttgg
    31381 aatatatggt attgtaaaat atcttataga aaaagatagg tctatatata ttgagtattt
    31441 tatgaaatta gtatttgcaa atataatgat acttatattg tattttttat taagaacaat
    31501 agtttatatt ccaataaaca tatttattat aggttcattt gagatagcct ttatagtata
    31561 tgactatgtt tacagttctt ttataggtta ttacaataat aggttaagaa agatgctatt
    31621 taaaaaataa tagttgattt ttatatttaa ttttaatgaa attgtagttt ggataagtgt
    31681 aaatgatata tctgaatata cattaaagca taaagctaaa tttaatatat tcttagtgca
    31741 acatataaaa gctttgattt ttagtcaaag cttttatatg ttagatataa atattagata
    31801 taatataagt ttttaaaata gatagtataa attaaatatc cactatattt acatctgtag
    31861 atagagaata aataatatct tttctttcta ctattatctc aacattttta gaaatttcct
    31921 catcaagtga tatttgagat aaaagttcct ttgttggatt tattgctatt ggatttccaa
    31981 ctctttttag catatttata tcaccattag tatctccata ggcatacgag tttgataaat
    32041 ctaaatcata ctttacaaca aaatcattta tagcattatt cttacttata gaatcccaca
    32101 ttggaataac tgtgcctgta aatatattat tttcaaagac ataatcactt cctagaaaat
    32161 cggttacatt atattttttt gccatttttt caacaagaaa tccagggcta ccagatataa
    32221 atataactat gtgtccttga tttagatgcc actcaatcct tgaacgtgtg tatttataaa
    32281 ctctatctgc ttttaattta attacttggt cacttgtaaa gttgatacag gttttatcta
    32341 atccttttag tgaatcaaca taaaggtcac atatttctaa tagataatca tcataattac
    32401 cttgtctttt atcccaatcc ataaaagtgt ctctagcatg tttataccaa tttttttggt
    32461 caattatatc gtatttaatt aattttttaa aatgttcaac cataagagag tctctataaa
    32521 gagtaccatc tatatcaaaa aaagctgcta tatttttcat aagaccacct caattaatca
    32581 tttccttata ttatattata aattgtatct aagttgttaa aatatatgta taataattta
    32641 tatattaaaa aacaagtatt ttagagttta aaggatgtga ctatatgaat tttaattttg
    32701 caaaggctac aaattctaga cttatgggca gtttaggtct tataataaat tggatagatg
    32761 atgaaaacaa tcacttttgt caatattttt tattagatgc agagggatta ggattagcag
    32821 attatgtgag tttaaataac ccaacacaag aagaagctta tatggaagaa gaaagattga
    32881 tgggaggatt tggttcagat agagttgaat taacgaagga tgaatcttta tttttagtat
    32941 cttattttgg taataagaat ctttattatg ataagctatt gccaggagat aaatgtgagt
    33001 atattgatat tataaaaaac tataaaacag atttaattat agaaaaatta tacaataaaa
    33061 tatgtaaaag agttgatgag gaagttgaat ttataaacta tatgactatg agatttatag
    33121 catgggatag agaaagttta aaatattttt ctggaagtga cgagattgca aatatgcata
    33181 ttactaatat aaatggaaca ttacttaaaa acgtggtaag tgataaaggt caaggcagat
    33241 atataagtga agctttatat gaagacaatg atggatatta tatatgtaaa attgcttttt
    33301 gcataagtaa gtgctatgaa actggtttta gaattaattc tctattagtg acagataaag
    33361 aacttatgta tgattttgag gtatttgatg agatttctaa aagtgaattt gtaagtgttt
    33421 acagtgtaaa ttcacctgaa gaatttgcag gagtatttta tagagaaaat ccatttctgt
    33481 taaaaagtaa tatgaatgaa ggtatatttt ttactagatt taattttaat aatgaccatg
    33541 taaaagaaaa tgtatatata ataaacaatg atatgaaagc tatatattac ttaatgggaa
    33601 ataagttttt tattggtact tataacgaaa atgattgcaa ttatatcaat gaaataagtc
    33661 agtctaatta tagtgactat attaaatttg aagagaaatt tttctttgag caaaatgcat
    33721 tatatgactt tgcagaatca ggttcattag attttgatga ttttttggaa taataaattt
    33781 agacattatt taagcgagat taactgaatt taatctcgct taaatttatt tctataatat
    33841 tgggggaata ttatgaggaa tacatttatt attgtggtca attattaaaa ttttatacag
    33901 tttattataa aaaatttata cttttcttta tgttgtttgc caatattagt ctcaaatacg
    33961 agtaccatac tattctgacc caccaacaca agaaagagtt ttttaaatga aaaagtcaga
    34021 taaaattaaa ttttatctga ctttttctat gtttatctta ttagattatg ttaatatctg
    34081 ttgaccgaat aagcgcatac tcagtcaact ttctatacct ataataatat tgggggaata
    34141 ttatgaggaa tacatttatt attatggtca attattaatg ttttatacaa cttgctcaaa
    34201 aaaatatata ttacatttct tcctcatcaa attcttcaat attagtagcc tgtggtatac
    34261 cttgtataga catattacta gaaccataag gagtaggata tatattagga ggcatagtac
    34321 taggcataac tacaggcata ccttgcattg tattatgaca tataactcct ggtatcatca
    34381 taagtacatt aggaggcata ttttgattac atgagaagtt aggaataccc atagtattat
    34441 tcatattata ccccatatta ctgttcatgt tattaggcac attgttaggc atacccatgt
    34501 tactattcat attattaggc atattgttag gcatacccat gttactattc atattattag
    34561 gcatattgtt aggcataccc atgttactat tcatgttatt aggcatattg ttaggcatac
    34621 ccatattact attcatattg ttagacatat tgttaggcat acccatgtta ctattcatgt
    34681 tattaggcat attgttaggc atacccatat tactattcat attgttagac atattattag
    34741 gcatacccgt attattattc atgttattag gcatattatt tgtagcagat gtattgtaat
    34801 tcatatttcc ggatgtatta tttgtgttag gcaagttgtt tggagaatta ctacttttag
    34861 gataatgatt tacattatta ggatataggt tatttatgtt ctggttatta ggtatttttg
    34921 tataaccatt agaaatttga gggtcatttc tcaattcatc ttggggaatt tcttcattag
    34981 taatataatc tgcatagttc gctgggtcta agtaaggcat gtaactagta tctaaatcct
    35041 tttttttctt gttactcata ttaaacttgc acctcctaga aaactataaa aaagtttaca
    35101 aaaacttatt ctaataatat atatattaaa aaagtttata atatgtgcat tctaattata
    35161 ttaaattaat aaaaattatt gttgcaaatt taggaatgat agcatataat gaacatatga
    35221 acagttattc atatattaaa acaatggagg attaaagatg agagaagaga taaatgattg
    35281 taattgtaat atagtacatg aagaaatagt aacagaggct aaatcaacta tgccagatga
    35341 agagatgtta tatgatttag cagaattatt taaagtattt ggggatacta ctagagtaaa
    35401 gatattatat gcattatttg caaatgaaat gtgtgtatgt gatatagcga gtttattaaa
    35461 tatgactcac tctgcaatat ctcatcaact tagagtacta aagcaggcta gattagtaaa
    35521 gtttagaaga gaaggaaaaa cagtgtatta ctcattagat gatagtcata taagccagat
    35581 atttgattgt ggattaaatc atattagaga aacttataaa tgataaatga gaggagtgaa
    35641 tatatatgga agcaaataat ttaattaaaa aagaatttat actaggagga ttaaactgtg
    35701 cacattgtgc agaggagatt aataataaag tttctaaact acaagaagtt aaatcttcca
    35761 acttaaattt tataaataaa aaacttatag taaatataaa ggaaagcttt aatgaggata
    35821 ctactataga aaagataata gatataatag attcaacaga accaggtctt gatatacaaa
    35881 taagttctaa agaaaatgca tctagtaaaa catcaattaa aaaagagctt atattaggag
    35941 gattaaactg tgcacattgt gcagaggaga ttaataacaa ggtttctaaa ttaaaagaag
    36001 ttgaatcttc taatttaaac tttgtaaata aaaaacttac agtaaatata agtaataact
    36061 ttaaagagga tgatgttata aataaaataa aagaaataat aaattcaaca gagccaggac
    36121 ttgatataca agtagggtct actgacaaag taaaagggag aactactgaa aaatcaggag
    36181 ctgtaaatga tacaaataag aaagaattag ttccacttat aattggagca cttgtatata
    36241 tatttggtat atatcaaaca gctacaggtt atgaaagtca gtttagcaat atagtattta
    36301 tagttgccta tgtaatagta ggtggcgatg tgcttttaag agcaataaga aatatatcaa
    36361 aaggaagagt atttgatgag aactttttga tggctctagc aacagtagga gcattaacaa
    36421 taggggagtc atcagaagca gtaggggtta tgcttttcta taaagtagga gagtatttac
    36481 aaggtgttgc agttggtaaa tccagaaagt ctataacttc acttatgcaa ataagaccag
    36541 attatgcaaa tctaaaattt aattctgaag ttaaggtagt gtcaccagaa gaagtaaatg
    36601 taggggatat aatagtagta aaacctggtg aaaaagtacc attagatggt gtagtagtgg
    36661 atggagtttc tatgctagat acttctgcac tcacaggaga gtcagtgctg agagaagttg
    36721 aaaaaggaga tgaaatctta tcaggtgtta taaataaaaa tgctttattg agtattgaag
    36781 ttacaaagag ttttggagaa tcaacagttt ctaagattct tgaccttgtt gaaaattcta
    36841 gcattaaaaa atcaaagaca gaaaacttta tatctaagtt ttcaagatac tatactccaa
    36901 tagtagtaat agctgcttta ttaatagcat ttgtgccacc acttgtaatc tcaggtgagg
    36961 tatttagtga ttggttatat agaggattga tattcttagt cgtttcttgc ccttgtgcat
    37021 tagttttatc aataccactt agtttcttta gtggaattgg gtttgcatct aaaaatggta
    37081 tccttattaa aggaagtaac tatttagaag ctttaagaag tgtagataca gtagtatttg
    37141 ataaaacagg aacacttact aaaggtgtgt tcaatgtaac taagttaaat cctgaaggta
    37201 tatcagaaga agaattatta gaatatgcag ctattgcgga ggtaaattca aatcatccaa
    37261 tagcaaagtc tatattaagt tactataata aaaaaattga tttagataca atagacagtt
    37321 atgaggaaat agcagcttat ggaattagag taaagcataa tggcaatttt atattagcag
    37381 gtaatgagaa acttatgaaa aaagaaaata tatcttattc atcagctaaa gaagtaggca
    37441 cagtagtcta tattgctgtt gataaagtat atagaggtta tatagttata tctgatgaag
    37501 taaaagaaga tagtaaaaat gccataagaa gcttaaaagc aataggggta aaagaagttg
    37561 taatgttaac tggagataat gagaaagtag caaaaaatat tgctcaagaa ttagaattgg
    37621 atacagttta ctcaaattta cttcctaatg aaaaggtaga tagattagaa gatttatatg
    37681 aaggaagaac tgaaaaagag aaaatagcat ttgtaggtga tggaataaat gatgctccag
    37741 tattagctcg tgctgatgtt ggtatagcta tgggaggctt aggttcagat gctgctattg
    37801 aagctgcaga tgtagtgctt atgacagatg agcctagcaa gatatctaaa gcaattgaaa
    37861 tagcaaacaa gactaataag atagtgtggc aaaacataat atttgctcta ggagtaaaaa
    37921 ttatagttat gatactaggt gctggaggag tagctactat gtgggaagct atatttgctg
    37981 atgtaggtgt ggcacttata gcagtagtaa atgctatgag agctatgaga taagggataa
    38041 atgtaaatcc atactattta aaaaacttat aattatatat tgaagtatgt aataatgaaa
    38101 ggtatcaata agtttctttt aactttattg gtaccttttt attggagcgc tttgcatata
    38161 taaatttata ttcattatcc attgtgttta tttaatgtat ttatttagtg tagagctttt
    38221 atattgtaat tttaaaattt agacatagaa ggtttattaa taagtctata ttaagtttaa
    38281 attagattca taaaaattat aatacttatg attgtatata tattatatta atagttataa
    38341 tttttacaac aaaatgtgtg tgttaaaata ctctaaacca acagtatgac tgtcattcaa
    38401 taaattatgt aatataagaa agtaaatatt tttaaaaaat aatttaaaaa agtattgacg
    38461 aaatattttt aaggtgatat agt
//
LOCUS       DAMJYN010000035        38359 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.036, whole genome shotgun sequence.
ACCESSION   DAMJYN010000035 DAMJYN010000000
VERSION     DAMJYN010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 38359)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38359)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38359
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.036"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            1..391
                     /locus_tag="PC466_001881"
                     /pseudo
     CDS             1..391
                     /locus_tag="PC466_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816433.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
     gene            complement(751..1905)
                     /gene="nagA"
                     /locus_tag="PC466_001882"
     CDS             complement(751..1905)
                     /gene="nagA"
                     /locus_tag="PC466_001882"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HDF2769266.1"
                     /translation="MKSFIYADKFFMKHGIKEKGYLSIINGKFGEFQQERPNITDNVI
                     DFSGKYIAPGLVDTHIHGLLGADVMDNTFEAINTISKGLLKYGVTSFLPTTLTDSVDT
                     LSDSVENISNSFNRVEGAKIQGIYLEGPFFTEKYKGAQNEKYFKDPDINILKLWQRKS
                     KNLIRKIAIAPERKGSIELTRYATKNNISVSLGHSSATFEQVKQVVNSGAKVFVHTYN
                     GMSPLNHREPGMVGAAMVLKDTYAELICDGHHVSPIAVKIMMDAKSSNNIALITDCMR
                     AGAMEDGKYTLGKFSVNVKNSVARLNSGSLAGSVLTMDKAVRNIVDWNIATLEDAIKM
                     ATYVPALSCNIDNVCGSIHQGMDADFIVTDKNFNIYETYISGICMYKVNK"
     gene            complement(1988..2713)
                     /locus_tag="PC466_001883"
     CDS             complement(1988..2713)
                     /locus_tag="PC466_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2769267.1"
                     /translation="MIKRNDKRPIYDQLVEILRTKIENEMEPNDRMLSERKICDEYGV
                     SRTTVRLAMAELEHMGYIYKRHGKGTFVAALSQNSQNLMESYSFTDYMRIQGKKPGTK
                     VLSFEVVESTKYFSEKLGITPGEKMIKIMRLRLADDLPMMLERTYLPMKEFIGLTKEK
                     IEQKPLYEIFREDYGEIIKVADEEFSAGIISDKEAKLLEVPGDSPCLKLLRTTYNDDN
                     IVIEFTLSVARSDKFVYRVRHVR"
     gene            2982..3911
                     /gene="pfkB"
                     /locus_tag="PC466_001884"
     CDS             2982..3911
                     /gene="pfkB"
                     /locus_tag="PC466_001884"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HDF2769268.1"
                     /translation="MITVITFNPSIDRMYKVNNINIGEVQRVVSKNATAGGKGLNVAK
                     VCKILKENPLAMGFLGGFNGEFIKNELRKLDIQNKFTKIEQETRNCLNIIEDNKVSTE
                     FLEKGPIVEKSDLERFENDIEEVLKNTKILVASGSYCENMPIDYYEKIGNICRANNIK
                     FILDTSGEALKIALKSKPYLIKPNIDEIRHLLGINIESREEIILSGKKLIEMGAENVC
                     ISLGKDGMVYLNEYNVYDVKVPVVKCINTVGSGDSTVAGFSVGILRGYKIENLLKFAN
                     ACGISNALNMETGFVDLGEIDKYQDLVEVKKLS"
     gene            complement(4040..4957)
                     /locus_tag="PC466_001885"
     CDS             complement(4040..4957)
                     /locus_tag="PC466_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HDF2769269.1"
                     /translation="MKNIKMGMIGLGSIAQKAYLPILTKSERFEFVGAFTPNKVKREK
                     ICSDYRIMPFDSIESLAKKCDCIFLHSSTETHYEIIKILLNLGVHVYVDKPLASTVNQ
                     GEELIELSKKKNLNLMVGFNRRFCPMYKEIKNNATEIVSINICKHGLNSLRNVRFDST
                     LIDDYIHVIDTALWLANEDVEISGEDLFLTDNKNLIFVSHKLKGKHFSVNTSMHRDSG
                     TKLEQVEILSKGKIQRVKNLNVLEIEEGGNLTLKQSGAWVNILKQKGFEDISNHFIDC
                     IENNIKPAINGEECIKAQRLLEKIINSVK"
     gene            5419..6588
                     /locus_tag="PC466_001886"
     CDS             5419..6588
                     /locus_tag="PC466_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HDF2769270.1"
                     /translation="MKMFKLEEQKLKDLGAIITTNEIKQQPELWLETYEIYKSNKEKL
                     NRFIDTISNNHGQFRVIFTGAGTSAYIGNSILPYLKNKNDIRKYIFEAIPTTDIVSNP
                     YDYLKKDIPTLLISFARSGNSPESLAALNLGNKIVDNFYHLAITCNPQGELAKMTKND
                     ENNYLLLMPSKSNDEGFAMTGSFSCMMLSAMLIFDSLEDDVEKSYINAIIEMGRNVID
                     RKDEIHELINKDFDRVVYLGSGGLGGLTQEAQLKLLELTAGKISTVYDSPMGFRHGPK
                     SFIDENTLVFEFVSNCLYTRKYDLDVLEEIKRDKIAKFTCAVSVENENNFSGTKFEFK
                     EKYNKLPDVYLAMPYILFAQTIALFVSVKVGNKPDTPSATGTVNRVVKGVTIYEY"
     gene            6637..7488
                     /gene="gatY"
                     /locus_tag="PC466_001887"
     CDS             6637..7488
                     /gene="gatY"
                     /locus_tag="PC466_001887"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit GatY"
                     /protein_id="HDF2769271.1"
                     /translation="MALVTTTSMLKKAQDEGYAVGAFNVENMEMVIAVIEAAEELNSP
                     VILQTTPSTVKYAGLDYYLANAKVAAERVKIPVAMHLDHGSSFDLAMKALRSGYTSIM
                     IDGSHESFENNISISKSVVKACSPSLIPVEAELGKVGGKEDDLDGGNSNDYTNPKEAK
                     EFVDRTGISSLAIAIGTAHGLYKGEPKIDLDRLSEIKNVVSIPLVLHGGSGIHDDIIK
                     EAIKRGIAKVNYATELRIAYSKGVKKVLDEDSEVIDPKKYGLAGLQSVKDFVKEKIKV
                     CGSVNRV"
     gene            7814..9715
                     /locus_tag="PC466_001888"
     CDS             7814..9715
                     /locus_tag="PC466_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDF2769272.1"
                     /translation="MRERIILETLKNSSGYLNIDYFADKLGVSTRTIRNEIKKIETIK
                     ECNGFKLEYKSKLGYILNIKDQDKFEHYLRNLPSDLVENPEQRLESIIVELLVNEGYK
                     TIEQLSKKFLVSSSQIKNDLKKIDEKIKDTELKLERKAHYGIKIEGSIKEIQSILVDS
                     YFRGNRNITEYRNKFIDNLKLANIRSTIKNVLNEHDLEANLTELEEILAQIIILYIRV
                     SMRVVGNASNLKLYTEDLIIDKLLDKIFRDKKYNLNYDEKYYLKELIKLKTKDKKATI
                     KNIDKNKLQDIMFEFFREIDKKYNSNFLEDKEFFNLFYLHIACLIERIKKNHKIINPF
                     SVKISQQYPTVFNLSIQFSKIIENEYHIKISQDEIGFIATHIAVPFEKREEANFNKKY
                     KIAIICSSGGGSAFLINLRLKEIFPNAEIRNFSLLEEKAVIEFAPDLIFSITNLLFEI
                     NAPVILINEILDELDYLDIKESVRFADHIGNISSPKQYILGLFDKNHFRCIKDKAKYK
                     DILDSMSKCIVDEGACSPTYPKDVWERESYLSTIYTNGVAIPHPIEMTGNKNIISVAL
                     IQTDIIYENRVPKIIFMISLIKGNLELHKQISKYLSKIMANKDMVDMLNKSQSYEEFM
                     YKLKIYLGG"
     gene            9718..10761
                     /gene="ypdE"
                     /locus_tag="PC466_001889"
     CDS             9718..10761
                     /gene="ypdE"
                     /locus_tag="PC466_001889"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HDF2769273.1"
                     /translation="MNIEFFKRLSEADGIASNEEEVRHVLLEELKAYSDKIICDGLGS
                     IIFSKIKDESAPNVMICAHMDEVGFMVRSIDKLGMIHLITIGGVKPLAQFVQKVRITT
                     KEGKKIPAVINATYNNGKAENIYADIGAYTEEDVYNLGINVGDMVTYTTSFEEFTLPD
                     RLVGKAFDDRIGCFVMGEVLKELRKENLNCNIHFAATSSEEVGIRGAKTSTQLINPDI
                     VFVIDVACAKNEFVRDYTNQKQIDKGVMLMHRDRTLVPSRKMIDYVMEIADKNNIPLQ
                     HDMFESGGTDGGEAHLVNEGKPCVVTCVPVRYGHCAFSIVSNKDLENIIRLYTQLILN
                     FDEEQYKHIRNFI"
     gene            10776..11081
                     /locus_tag="PC466_001890"
     CDS             10776..11081
                     /locus_tag="PC466_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HDF2769274.1"
                     /translation="MSTEVQIMELISTAGESKSKAFEALKKVKSKDFKGAKLLIEEAR
                     KIDIEAHRIQTELITQDLNEDVESPTMSLLMVHAQDHYMTSQLAKDLIEALIYCLDK"
     gene            11178..11513
                     /locus_tag="PC466_001891"
     CDS             11178..11513
                     /locus_tag="PC466_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2769275.1"
                     /translation="MKILLCCAGGFSTNMLMQNMKKVVKESAKLNEKDFEFTAIPADS
                     IESEVDDWDIVLIGPQIAHKIDFLKGILEPKNKPFAVIDKDVYGKMDGATVMKLALIT
                     YKKHQLAQG"
     gene            11545..12867
                     /locus_tag="PC466_001892"
     CDS             11545..12867
                     /locus_tag="PC466_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF2769276.1"
                     /translation="MFSKFEAFMNRVFMPLAHKVDNQRHLGSIKAGMVAMTPFTILGS
                     IFAILPALPNMLGENNPISKFILNNSAILDLPVSLSIGLIGLYACMCIAFNLGNYYKL
                     YIPGCVALSTFSFLFLVASFTPDGALEIGNLGAKGLFTGMIAGLGSVELYNFCNKKNI
                     TIKMPENVPDFVSRSFELIPTTIIVCGTFIVARFISLKVFGELPPQILTQFLSPLVGS
                     MDNPWSVLALNFAICTIFFFGIHSSVFSPITRPIMITFIAENIAAMQAGETIPHFFTA
                     GASSAFFGFTGCGISIGCVIACMLSKNASYKKIGRVSLFPALFGINEPILFGAPIILN
                     PIMFIPHVFGGAIIGTLPMFFMHWGWLAKPVFDPPYVGVFLEGFLTNGDWHSILANAL
                     QLVLAVLLYWPFFKIMERQQNNKKQKEETKNIFSKEEEDLLDDLGLDF"
     gene            12877..13947
                     /locus_tag="PC466_001893"
     CDS             12877..13947
                     /locus_tag="PC466_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HDF2769277.1"
                     /translation="MNNTIERLVSLIYKRGVDALLIKAKNTKRYIGALSGSGVYVLVT
                     KDKNYQILDGRYIDEADKKTTGFIKRIVSQGSYIPTIIELLKELNIKKLAIENQAMSI
                     QEYLSLKNEGFEINLITNELWKLRAIKSKEEIELIKKACEITDEVFDEVISEIKKDMT
                     ELEVSALIQYHALKKGASGMSFETIVVSGERGAMPHGRPTNKKLKVNEAITIDFGVVY
                     QGYQSDMTRTISIGKPPKIIKEIYDVVLEAQLSAIESIKEGTRASDVDKVARKIIDKH
                     GFGEYFNHGLGHGIGLGDGEVPTLNPNSEDILVEGMVMSCEPGIYIPNVGGVRIEDDI
                     VIIDGKGVPLNKTSKEFIILGE"
     gene            13952..15139
                     /locus_tag="PC466_001894"
     CDS             13952..15139
                     /locus_tag="PC466_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HDF2769278.1"
                     /translation="MKYNFNKVLNRKEGNCRKWSNHVIKEKFGLNEDAIPMDLADIDF
                     ECAPAIKESILKRASVGDYSYTFIGDDFYDAIINWNKRRFDVYIEKDWIKLTFGTVST
                     LHYIVQAYTKEGEGVLINTPAYDPFAEAVANNNRKLCCSSLKLDNNRYYLDLEDMENQ
                     MKYENIRLLIFCSPQNPSGRIWTKEELYQVSELCLKYNVILVSDEIHRDIIFKDYRFV
                     SLWNAHPEIYKNSIICVSPNKGFNLGGLKTSYVLIRDVKIRETLLERLKSNSITSPNV
                     FAIPAIVAAYNESEEWLDAMTSYVEENFEIVYDFFETNIPKAKVMKSDSSFLAWIDVR
                     EVFRNEEESKEFFRHANLTMVVGSYFVKDGDGFIRINVGCPRETLNEALNRIKKTYIS
                     MYC"
     gene            complement(15336..16208)
                     /locus_tag="PC466_001895"
     CDS             complement(15336..16208)
                     /locus_tag="PC466_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HDF2769279.1"
                     /translation="MNILQNENLIIESSSFGAELTKIFSKKYDKNILWDGNKKYWGRQ
                     SPILFPIVGKLFDNETIIEENLYSMTQHGFARDMDFEIVDKGDTFVSYKLTDNESTLK
                     KYPYSFELIINYTLNDNSIEVEWIVKNTDSKDIFFSIGGHPAFNLPFYKQNDFSKHYL
                     EFKSKNDVEKINLNGSFTDDIIPIGKLKNLHLNPEVFKNDALIYTNIDEVSIYNNDGS
                     KYVTISMEDFPLVGIWTPYYSETNSTAPFLCIEPWYGLADSINSNKIYKDKKFINKLS
                     KGKVFTASYNINIH"
     gene            complement(16602..16793)
                     /locus_tag="PC466_001896"
     CDS             complement(16602..16793)
                     /locus_tag="PC466_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769280.1"
                     /translation="MDDFSKLKSLYEDGYRCIYHDCVDNNYTIYLKNFYTEGSETIEL
                     SSESDFSQFKDYIDGLRMS"
     gene            17013..18059
                     /gene="cobT"
                     /locus_tag="PC466_001897"
     CDS             17013..18059
                     /gene="cobT"
                     /locus_tag="PC466_001897"
                     /EC_number="2.4.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide--dimethylbenzimidazole
                     phosphoribosyltransferase"
                     /protein_id="HDF2769281.1"
                     /translation="MSLLESISKNIYSLDNSSIEKTKQRLDRLIHPTGSLGKIEDICM
                     QLAGIFGNENFDTSKKVIIAFAGDHGVYEEGVAPDPQNITKLQFPNFSKGLCGVGVIS
                     KFVGADVVAVDVGINCDEKLDGVLDYKIRKGTSNMAKGPAMSKQEAIRCLEIGIEIAE
                     QCIEKDYKVIGIGEMGIANTTPSTAIISVISGCDPLEVTGIGAGLKKERLKHKAEVIR
                     KAIEINNPNPTDGVDILSKVGGFEIGSMAGVILGCSANRIPVVIDGFISYAAALIAYK
                     INPKTREYMIASHLSAESGTKRALDILKLDPLLNMDMRLGEGSGAALAFDIIEASNYT
                     YKNMATFDEIDMGR"
     gene            18091..18651
                     /gene="cobU"
                     /locus_tag="PC466_001898"
     CDS             18091..18651
                     /gene="cobU"
                     /locus_tag="PC466_001898"
                     /EC_number="2.7.1.156"
                     /EC_number="2.7.7.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional adenosylcobinamide
                     kinase/adenosylcobinamide-phosphate guanylyltransferase"
                     /protein_id="HDF2769282.1"
                     /translation="MSKIILVTGGARSGKSNFAEKLCFDRNNNTAYIATSIPFDDEMK
                     DRVKKHQENRPRNWNTYEIYEDIYSIIKEIYKEHETVILDCVTLLVNNLMFEHNLNIE
                     ESSQEEINKLEQYIKEQVVKLIEEIEKTNLYFVFVTNELGMGIVPGNKLSRIYADIVG
                     RINQYIASKSNEVYFVVSGIAMKIKE"
     gene            18661..19434
                     /gene="cobS"
                     /locus_tag="PC466_001899"
     CDS             18661..19434
                     /gene="cobS"
                     /locus_tag="PC466_001899"
                     /EC_number="2.7.8.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobinamide-GDP ribazoletransferase"
                     /protein_id="HDF2769283.1"
                     /translation="MKRFILILQFLTRIPIKLNVGFDDEFYKSIVYFPLVGFVIGILS
                     YLIGWISMLLFEPFIASIIITLAGVLITGGLHIDGLGDTFDAIYSYRDKEKMLEIMKD
                     SRLGTNSLLAIMFVLLLKVGFVYDIISNNSLWIIIFMPMIARLGVMLLTYKTVTPREK
                     GMGNLFIGKLTTSMLITAIIYTLLIVALITKFIFLLPNIVLIKVLGSIIVVFVFIILF
                     KKHIYKKIDGVTGDILGCGIELSELVYLIYIYLLIFMFF"
     gene            19454..20068
                     /locus_tag="PC466_001900"
     CDS             19454..20068
                     /locus_tag="PC466_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HDF2769284.1"
                     /translation="MIRLILIRHALTNDNKKGRLSGHINSCISEEGKLQINKITRYLS
                     NENIDKVYTTPSTRTKDTVEKISKLKLLEIEEKEALREISFGDFEGRTFEEIKIKYPN
                     EFEKMIKEGNNYRYPNGESLIDSYKRVAKEIDNIILENDSNLDTKTILICSHAGTIRN
                     IITHLISGSYKYHWNFKIDNASITVLEIDGGFAVIDKMNFTDFI"
     regulatory      20135..20314
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            20444..21943
                     /locus_tag="PC466_001901"
     CDS             20444..21943
                     /locus_tag="PC466_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobyric acid synthase"
                     /protein_id="HDF2769285.1"
                     /translation="MLQGTASNVGKSVLVAGLCRIFKQDGYTVAPFKSQNMALNSFIT
                     KEGLEMGRAQVFQAEAAKIEPIADMNPVLLKPSGNNKSQVIVRGKVVGEMPSSKYHDY
                     KLELVGVLKETFNSLNSRYDIVVMEGAGSNAEINLKDRDISNMGMAEIADAPVIIVGD
                     IDRGGVFASLAGTMLLLNEDEKRRVKGVIINKFRGKKELLQDGVKMLEDIIKVPVIGV
                     VPYTDIKIEDEDSVTTRFKKKMNKSDIHIEIIRTPHMSNFTDFNIFETQEDVSIRYVD
                     YGESLGNPDILIIPGTKSTIDDLTYIRKSGLESQIKNLHSQGKLIFGICGGYQMLGKK
                     LKDPYHVESEIEEVDGIGLLDTETTFEKEKTTTQVEATIVECISEYMNNLKGKKVKGY
                     EIHMGITKRGNDVRSLDLITKKLDKEVNYTEGSVNKEGNVIGTYLHGIFDEISFTRAI
                     LNNIRKKKGLGELESKVNSFNEFKDKEYDKLADFLREHLDIEKIYEIMK"
     gene            21982..23358
                     /locus_tag="PC466_001902"
     CDS             21982..23358
                     /locus_tag="PC466_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobyrinate a,c-diamide synthase"
                     /protein_id="HDF2769286.1"
                     /translation="MKKILIAGTNSGVGKTTISLGIMQALVKRNMKVQPYKVGPDYID
                     PSYHTFITGRHSRNLDSYMLDDEKIKYIVNKSSKDADISVIEGVMGLYDGFGIDLDNC
                     TSSHTSKVLKSPVILVINGKSMAASSAAMVLGYKELDKDVNIKGVIVNNVKTNSHYQI
                     IKSSIEKYCNVEVLGYFPPNNKFSLESRHLGLVPSVEMKSLREKFYTLADEIEHYIDI
                     DRIIEISESDEFESDFDFQTLIENNKIKEHVNNKSIAIAYDKAFNFYYRENIELLEEL
                     GLEINYFSPLEDASVPNADYIYIGGGFPEIFGKELEANESMRTSILEAHNNNIPIYAE
                     CGGLMYLGEKLLNQEEQEFNMVGIFSGISKMTSSLKRFGYCIGVAKENTLLSKKGESI
                     KGHEFHHSIFESDEKCVYSMRKERDGNIVEEWDGGYSKGNTLATYLHTHFYNNLNCIE
                     NFLKKGNE"
     gene            23359..24330
                     /locus_tag="PC466_001903"
     CDS             23359..24330
                     /locus_tag="PC466_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin biosynthesis protein"
                     /protein_id="HDF2769287.1"
                     /translation="MSILSIYIGYVTDLIVGDPYSFPHPVRFIGKLINFTQGIIRKVS
                     KNDRQLKFGGFILWFITVGITYLTTYAIVKLFSFNILLSIVVNSFIIYTTLATKCLKD
                     EALKIYNVLKTEDIEKSRIQLSYIVGRDTTNLSEPEIIRATVETVAENTVDGIIAPMF
                     YAFIGGAPLAMAYKAINTLDSTVGYKNKKYKDIGFASAKIDDIANYIPARISVILMTI
                     GSFFLNYNYRNCFKISIRDRKNHKSPNCAFSEGAVSGALGIQLGGTNVYFGEKVYKPT
                     IGDKLREIDKEDIIKTNKIMYVSSFVSMLVFTLIHVLCRMILINLII"
     gene            24362..25432
                     /locus_tag="PC466_001904"
     CDS             24362..25432
                     /locus_tag="PC466_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HDF2769288.1"
                     /translation="MKDLGHGANVGEMARLYGKNPKEIIDFSSNINPNVLPNLERYIL
                     KGLEECRNYPDINYTNLRENISKYIGINPDFIIPGNGATEVIYLLMKSVKKKLAIINP
                     TFSEYRRSAELNNLDIIDLELDLENNFKLNIDIIKENIKRFDSLFICNPNNPSGNVQD
                     LKELVHLLGKHNKVLIIDETFMEFVEDESKYSLVKYIESNKNIFIIKAVTKFFGMPGL
                     RLGYGLTSNTEIMNKIYEHKEPWTINSFADILSNFIFEDKEYIKNSKEYYIEERKYML
                     QELRNIRNIKVYDTDANFILIRAYKKTTKELKKDLLKQGNILVRDASNFIGLDDSFIR
                     VAIKSHEDNKILIENMKNLLGD"
     gene            25434..26321
                     /locus_tag="PC466_001905"
     CDS             25434..26321
                     /locus_tag="PC466_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin biosynthesis protein"
                     /protein_id="HDF2769289.1"
                     /translation="MKSYGICPASCGEFVQGIIDDEEYLCSYAIDMYSEVYIEEKLVD
                     INLGRYKSRLAIEKVFEKFNLPKKYTKNISLNINSKIPVGKGMASSTADIGATIKATL
                     SLIDKDLSSEEISKLAAEIEPTDSIFIDKNSIFNPLNGTVIKYLGNLTNAKVIILEPN
                     KVLDTMKIRLRQDYNKLKVENKEVIKKSFALLEEGLKKNNLSLVGEACTLSSLANENI
                     EKKEYLNEIIKISKKYGAYGVNIAHSGTVVGILIDKSMNDKKMIDTLCESNINSVYNK
                     IYTQNIINGGIKGEIEWNT"
     gene            26309..26941
                     /locus_tag="PC466_001906"
     CDS             26309..26941
                     /locus_tag="PC466_001906"
                     /EC_number="5.4.99.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003724727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-8 methylmutase"
                     /protein_id="HDF2769290.1"
                     /translation="MEYIKNPMKIEEKSFELIQEIIDEIRPDYKFKNNIEEKIIKRAI
                     HTTADFDYLDILKISEEAVDSIIDALKNNASIYTDTNMALSGINKRKLESLGCKYKCL
                     VADDETVKLAKEKGITRSMAAVEIAAKEEGRKIFVLGNAPTALYKVMEMKSEGRLDLD
                     AVIGVPVGFVGAQESKDEVEKTDIPYIISKGRKGGSNLAAAIVNAILYTM"
     gene            26950..28176
                     /locus_tag="PC466_001907"
     CDS             26950..28176
                     /locus_tag="PC466_001907"
                     /EC_number="2.1.1.195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-5B (C(1))-methyltransferase"
                     /protein_id="HDF2769291.1"
                     /translation="MEEYVYIDGKKYRRGYTTGSCATGASKAAVYMLITKNRINTINI
                     DTPKGIPLLLKVDNINISDTFVECSIKKDGGDDIDATHTMDIYARAEIVAKNDKNKGY
                     LTLKDIDSLSTNSECKSELYKFIRVYGGTGIGVVTKKGLSVDVGKPAINPTPLKMINH
                     EIRKLIGDNFESILGNDKVLKITIFAPQGETVAKKTFNPRLGIVGGISIIGTTGIVEP
                     MSDEGWKKSLSIELQMKKEQGLDKIILVPGNHGEQFIREKLNLDIKYVVRVSNFIGYM
                     IKEAQRIGYKKILMAGHIGKFIKVSAGIFNTHSKVADARSEILVANLALMGARYEFLN
                     KINQCVTTEEAVELINNSEYREVYNILSNKCKERVKQYLNEDSDDIDVEVIIFSMDKS
                     LLGKSDNTDDLVEVFI"
     gene            28173..28781
                     /locus_tag="PC466_001908"
     CDS             28173..28781
                     /locus_tag="PC466_001908"
                     /EC_number="2.1.1.289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-7 (C(5))-methyltransferase"
                     /protein_id="HDF2769292.1"
                     /translation="MINIIGLGPGNLDYITKKGENLISTSDVLIGGKRNLESIKNFEG
                     EKIVLDSNLREIIEYINNNKEKQISIIASGDPLIYGIGRYLSKNIDNKMLNVVSGISS
                     LQYIFSKIYVDMNDVYITSSHGKIPDFDYILSHKKVCMVTDSKIGPKQISREIIDRNL
                     NKIIVVGENLSYDNEKITIAKPEEIIRMDNFDMNVVVILDEE"
     gene            28771..29346
                     /locus_tag="PC466_001909"
     CDS             28771..29346
                     /locus_tag="PC466_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating cobalt-precorrin-6B
                     (C(15))-methyltransferase"
                     /protein_id="HDF2769293.1"
                     /translation="MRNSEFITGKVPITKEEVRAISISKLNLVNAKNLIDIGAGTGSV
                     SVEAAYNYPNLKVISIEKNDDAIELIEKNIKKFNLKNIEVIKGYAPINLGLNVKVESI
                     FLGGTGNNLEEIIEWSKKNLVTGGRLVANFIIIDTFNQTLKLLKKHGFKEIDVCVLNV
                     SKLEKLGKGEYFKPLNPIYIISCEKGENDDE"
     gene            29339..30091
                     /locus_tag="PC466_001910"
     CDS             29339..30091
                     /locus_tag="PC466_001910"
                     /EC_number="2.1.1.271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-4 methyltransferase"
                     /protein_id="HDF2769294.1"
                     /translation="MNKVHFVGAGPGDKELITLKGYKLLSNADVVIYAGSLVNPELLE
                     YCKEDCQIHNSAHMDLQEIIDVMREGIENNKSVVRLQTGDFSIYGSIREQVEDLNKLN
                     IDYDCTPGVSSFLGAASSLGVEYTVPEISQSVIITRMEGRTPVPEKESIQSYAKHQTS
                     MVIFLSVQEIEKVVSKLLEGGYPKDTPIAVIYKATWADEKIVKGTLSDIAVKVKENNI
                     NKTALIMVGRFLGEEYNNSKLYDKDFKHEYRG"
     gene            30075..31196
                     /gene="cbiG"
                     /locus_tag="PC466_001911"
     CDS             30075..31196
                     /gene="cbiG"
                     /locus_tag="PC466_001911"
                     /EC_number="3.7.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin 5A hydrolase"
                     /protein_id="HDF2769295.1"
                     /translation="MNIEGNIAIICITENGKNLAVKINSLVNNCVIYQVKNKKSNLVV
                     EETCVHTVQKKLSDFVGEIFSKFDYIIFIMATGIVVRSIAPYIISKFSDPAILVMDEK
                     GKNVISLLSGHIGGANSLTQYISSLIDANPVITTATDINQKASLDMIAKKLNAHIDNF
                     RESVKEVNSMLVNNKCVGLYVDEGYQVDTRGFKLIESKDELRDSFSNTYIEKLVVVSN
                     KINCIEDIENLNLDNKFEHCYSTKKIIKVIPRDIVIGIGCRRNTDSELMYNSLEEFLN
                     KQNIDIRAINTVGSIELKKDEKAIIELSKILKVPFKTFSIDEISKVDNLFDKSDFVKK
                     NVGVYSVAEPIAYLLSKGNLLVEKHKYKGITFSVGRIKI"
     gene            31193..31918
                     /gene="cobJ"
                     /locus_tag="PC466_001912"
     CDS             31193..31918
                     /gene="cobJ"
                     /locus_tag="PC466_001912"
                     /EC_number="2.1.1.131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011701973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="precorrin-3B C(17)-methyltransferase"
                     /protein_id="HDF2769296.1"
                     /translation="MIYVVGIGPGSKDTMTLEAIKAIEDSEAIVGYKTYIKLIEEFIQ
                     GKEIIQNGMRQEVDRCKQAVEEAKKGKKVAVVSSGDAGIYGMAGLILELISKEDEDIK
                     VKVIPGVTASIGAAAILGAPIMHDFCHISLSDLMTPWEVIEKRLRLAAEADFVICLYN
                     PRSKGRSEHLSKAFKIMGEFKGGDTPVGVVKDVGREKEEKFVCTFENMDFEKVDMTTM
                     VIIGNKSTYINGELMITPRGYTV"
     gene            31915..32667
                     /gene="cobK"
                     /locus_tag="PC466_001913"
     CDS             31915..32667
                     /gene="cobK"
                     /locus_tag="PC466_001913"
                     /EC_number="1.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="precorrin-6A reductase"
                     /protein_id="HDF2769297.1"
                     /translation="MILILGGTSDSLSICDKINELKNQPYILSVTTDYGRELAQQHAE
                     NVILGKLGKEDMLKFIKDNNIVKIIDATHPYAVEVSKTAITCAKLLNIDYIRFERKSL
                     IEEIDYDNKFIVDTIEEACEIANKIGTNIFIGTGSKNLNRFIEEISDKNLVVRVLPTS
                     EVILSCEKLGLSADNIVAMKGPFSQYINEETYKHYNIDLVITKESGIAGGFLEKVNAC
                     KTFNIPVIIIKRESINYENVFNDINKIKDILV"
     gene            32686..34164
                     /locus_tag="PC466_001914"
     CDS             32686..34164
                     /locus_tag="PC466_001914"
                     /EC_number="2.1.1.151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-factor II C(20)-methyltransferase"
                     /protein_id="HDF2769298.1"
                     /translation="MKKALLVVSFGTSYHETREKTIDICEDKIKNSLKSHDFFRAYTS
                     NMIINKIKKRDGIEIDNPIQALDKIYEQGYDEVIIQTLHIICGEEFNKLKEQVDGYSS
                     KFKKIVLGRPLLTHIEDYQEAVEAIKHQIPHMESNEAVVFMGHGTLHESHSAYPALEY
                     MLRDNGINAYVGTVEGYPEIEHVIRRLKEGNIKTVNLMPFMLVAGDHAINDMAGDEED
                     SWKTILEEDGFDVRVHLKGLGENSYIQDKFVRHAVKCAENAKFYGIGAGPGDGSLLTI
                     KAVNTLKKLDILYTPESKKGGDSLALSIVSEYLPESVEIKSRHFPMSFDGNEKSLAWD
                     NVAQEIISDVNDGKNVGFVTLGDPMIYSTYVYIMKRILGEVEVETIPGISSFSNIASN
                     QNFPLVMDKEALVVIPCTMEDDKIEYALQNYNSIVLMKVYKNFKEIIKKLEKYDLIEH
                     AILVSNSSQESENVFTDLKEAHLEDKISYFSTILVNKDNKIK"
     gene            34194..35099
                     /gene="hemC"
                     /locus_tag="PC466_001915"
     CDS             34194..35099
                     /gene="hemC"
                     /locus_tag="PC466_001915"
                     /EC_number="2.5.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylbilane synthase"
                     /protein_id="HDF2769299.1"
                     /translation="MNIVVGTRGSTLALIQTEWVINELKKKYPEISFEIKIIKTKGDL
                     IQNVSLDKIGDKGLFVKEIEQQLLDGKIDIAVHSMKDMPSYLADGLKFAHTPKREDPR
                     DVLILREGYKNLDDLPHGAVIGTGSKRRKFQLLKQRPDLNIVQVRGNVETRIRKIKDE
                     NMHGIVLAASGIIRANLQDKISSYLPVDVVIPAPAQGALAIEIRSNDSTIEGIVNSLK
                     DENTEIQILAERGFLDGVNGSCHIPMAAYCEIIQDKIHLTGLYGDSEGKKVVIKSIDG
                     DISSPRELGLKLAKLVLKEYENYEG"
     gene            35089..36588
                     /gene="cobA"
                     /locus_tag="PC466_001916"
     CDS             35089..36588
                     /gene="cobA"
                     /locus_tag="PC466_001916"
                     /EC_number="2.1.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen-III C-methyltransferase"
                     /protein_id="HDF2769300.1"
                     /translation="MKGKVYLVGAGPGDYKLMTLKGLECIRKSDVIVYDRLANSSYLR
                     EAKPDCELIYVGKASSNHILPQEDINRIIAEKAKEGKIVTRLKGGDPYVFGRGGEEAE
                     TLVDEDIEFEVVPGITSAIGGLCYAGIPITHRDHASSFHVITGHLKGDDSGELNWNAL
                     ANNKGTLVFLMGISNLEKISENLMKEGKDKDTPVALISWATRYNQRVVTSTLENVYET
                     AIKEEVKPPTLIVVGSVVGLREKLNFFESKPLFGKSIAVTRSRNQNSVLVEKIMDLGG
                     NPIEIPTIKVEKIQNNINLENEIKNINKYNYLILTSKNAVEIFFEKIYEMNFDLRILS
                     NLKVCAIGSATSNELKKRGIIADIVPKKFVAESLYEELAPILNDNDNILIPRAENARD
                     YLVDKLKAICEVTEVHIYRTVIDEDKKGEILDILNSNDIDYITFTSSSTVNNLVEIIG
                     KENIKILEKIKTLSIGPITTETINSLGIKLYKESATSTIDSLVDLIIKN"
     gene            36605..37570
                     /gene="hemB"
                     /locus_tag="PC466_001917"
     CDS             36605..37570
                     /gene="hemB"
                     /locus_tag="PC466_001917"
                     /EC_number="4.2.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porphobilinogen synthase"
                     /protein_id="HDF2769301.1"
                     /translation="MLRRPRRLRASKAIRNLVRETKVNVEDLIYPLFVVEGENIKEEI
                     NSLPDVYHLSIDMLEDEIKEISELGIEHIMLFGVPDEKDECASQAFNDNGIVQKAIRK
                     VKEINSDINVITDVCMCQYTSHGHCGILTDTGYVDNDKSLEYLAKISVSHAKAGADMV
                     APSDMMDGRIQAIREALDENGLENVGIMAYSVKYASNYYGPFREAAHSAPSFGDRKTY
                     QMDPANSNEAIIETELDILEGADILMVKPALSYLDIIRRVKDNFDLPLAAYNVSGEYS
                     MLKFAVKEGLLNEDVILESITSIKRAGADIIITYFAKDIAKLLKK"
     gene            37723..38301
                     /locus_tag="PC466_001918"
     CDS             37723..38301
                     /locus_tag="PC466_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional precorrin-2
                     dehydrogenase/sirohydrochlorin ferrochelatase"
                     /protein_id="HDF2769302.1"
                     /translation="MLYPINLKLDELDVVIIGGGEVAYRKCKNFLEFNKNVTIVSKQI
                     LNKFYDLKGNIKIIKDDYKEIYIKDASVIIAATNNRELNMEIGLYCRAKNKLVNVVDN
                     IEISNFTVPSYIKRGDLLISVSTGGKSPSLSSKIKKEIEERYTEDYEEYLNVLGDIRK
                     KVIKKYEDKSKRKDVLNMLVTLDLEELKKFDI"
BASE COUNT        15289 a         4047 c         6817 g        12206 t
ORIGIN      
        1 tgcaaaagat taaaagaaag tatatgctgc aattacagag gaagtagcat taagtgagct
       61 atcgctctta gaggaaaaat ggggtaatca atatgcgata gcattaagaa gttggcgaag
      121 caattgaaat gagctagcaa catactttaa atatcctcaa gagataagaa cattgatata
      181 tactacaaat tcaatggaaa gttacaatag attattaaga aaagttacta aatcgaagtc
      241 tatttttcct ttagatgatt ctttgcacaa atcattatac ttagcaacta tggatatttc
      301 tgaaagatgg actcaaaaga ttagaaattg gactcaaatc ttagctcatt taagtattta
      361 ttttgaagaa agaattttaa ctctaaatta ataaagaaat atttcaaaaa aattaaggaa
      421 ttttcttaaa ggggtaataa tttttacaaa aatggaaaaa atatcaaaat aaggctatga
      481 tttttaaagc catagcctta ccaataaatg tttaattatc actaaaaaat aaatttttat
      541 tcaaagaata cacataaata tttccagatt cttaatttta taaacttata ttgtaaaata
      601 aagaacctta ataaaaggag tgtctcaaaa ttaacttttt agtttatgag gcactctttt
      661 tgtatgaaat caaatgtatt ttcatcattt taacaatgaa aaagagactt atctctattt
      721 ttaggaagcc tccataactt tatattgaat ctatttatta actttgtaca tacatatacc
      781 acttatataa gtttcgtata tattaaagtt cttatctgtt actataaagt ctgcatccat
      841 accttgatgt atggagccac agacattatc aatattacaa cttaaagcag gaacatatgt
      901 agccattttt attgcatctt ctaaagtggc tatgttccaa tcaactatat ttctcacagc
      961 cttgtccata gttaatacac ttccagctaa actcccacta tttaatcttg caacactatt
     1021 ttttacattt acactaaact taccaagagt atattttcca tcctccatag caccagccct
     1081 catacaatct gtaattaaag ctatgttatt actagacttc gcatccatca ttattttaac
     1141 agctattggg cttacatgat gaccatcaca aattaattca gcataagtat cttttagtac
     1201 catagcagcc ccaaccattc caggttctct atgatttaaa gggctcatcc cattatatgt
     1261 atgtacaaac actttagcac ctgaattaac gacttgttta acttgttcaa atgtagctga
     1321 actatggcca agagaaacag agatattatt tttagttgca tatcttgtta attctattga
     1381 acctttacgt tctggagcaa ttgctatttt tcttattaaa tttttcgatt ttctttgcca
     1441 taattttaat atattgatgt cagggtcttt aaaatatttt tcattttgag cgcccttata
     1501 tttttctgta aaaaatggac cttctaaata aatcccttgt atttttgcac cctcaactcg
     1561 attgaagcta ttgcttatat tttctacaga atcacttagt gtatctacag aatcagttaa
     1621 agttgtaggt aggaaagatg ttactccata ttttaataag ccttttgaaa ttgtgtttat
     1681 tgcttcaaat gtattgtcca tgacatctgc acctaaaaga ccgtgaatgt gagtatcaac
     1741 taagccagga gcaatatatt tacctgaaaa atctatgaca ttatcagtaa tattaggtct
     1801 ttcttgttga aattcaccga atttgccatt aattatacta aggtaacctt tttctttgat
     1861 tccatgtttc ataaaaaatt tatctgcata aataaaactt ttcaaaataa cctccttata
     1921 attatactat cattgtggca ttgacgttta taatatcatt ctattttctt gaaagctatt
     1981 taattcacta tcttacatgt cttactctat atacaaattt atcgcttcta gcaacactca
     2041 aagtaaattc aataactata ttgtcatcat tatatgtggt acgaagtaat ttcagacaag
     2101 gtgaatctcc tggtacttcc aataacttag cttccttatc agagattatt ccagctgaaa
     2161 attcttcatc agcaacttta ataatctcgc cataatcttc tctaaatatt tcatataaag
     2221 gtttttgttc gattttttct tttgtcaatc ctataaattc tttcatagga agatatgttc
     2281 tttcaagcat cataggaagg tcatcagcaa gtcttaaacg cattattttt atcatttttt
     2341 caccaggagt tatacctaat ttttcagaga aatactttgt actttctact acctcaaatg
     2401 ataatacctt tgtacctggc ttttttcctt gtattctcat ataatctgta aagctataac
     2461 tttccattaa gttttgagaa ttttgactta gtgcagcaac aaaagttcct tttccatgtc
     2521 ttttgtatat atatcccata tgttccaact cagccatagc tagtctaact gtggttctac
     2581 ttactccata ttcatcacaa atttttcttt cagaaagcat tctatcgttt ggttccatct
     2641 cattttcaat cttagttctt aatatctcaa caagctggtc atatattggt cttttatcat
     2701 ttctttttat cataaaaaca tagtcctttc taagtggtta ttaccacaat ttgattatag
     2761 aatatagaat tatttatgtc aatgaataaa gtttaatcaa aattcaataa gtaaggctat
     2821 taatttatta taaaattatg gtatattgac aaaacaagta aaataattta tattcaaatt
     2881 ggtaataacc actttgggta tattatagat gaggtatttt ttattttaca gattaattta
     2941 ttgtttagaa aagtaaaaat taataatgag gagaatctag tatgattaca gtaataacat
     3001 tcaacccatc tatagataga atgtataaag tgaataatat aaacataggt gaggtgcaaa
     3061 gggtagtaag taagaatgca actgctggag gtaaaggatt aaacgtagct aaggtatgta
     3121 aaattttaaa agaaaatcct ttagctatgg gatttctagg tggatttaat ggagaattta
     3181 taaaaaatga acttagaaaa ctagatatac aaaataaatt tacaaaaata gagcaggaaa
     3241 ctagaaattg cttaaacata attgaggaca ataaagttag tacagaattt ttagaaaaag
     3301 gaccaatagt agaaaaaagc gatttagaga gatttgaaaa tgatatagag gaagtactaa
     3361 aaaatactaa aatactagta gcttctggta gttattgtga gaatatgccg atagattatt
     3421 atgaaaagat aggaaatata tgtagagcaa ataatataaa atttatatta gatacatcag
     3481 gagaagcatt aaaaatagct ttaaaatcaa aaccatattt aataaagcca aatatagatg
     3541 aaataagaca tttattagga ataaatatag aatcaagaga ggaaattatc ttgtcaggaa
     3601 aaaaacttat tgaaatgggt gcagagaatg tatgtatatc tttaggaaaa gatggtatgg
     3661 tgtatttaaa cgaatataat gtatatgatg taaaagtacc agttgtaaag tgtataaata
     3721 ctgtaggtag tggagatagc acagtggctg gatttagtgt aggtatttta aggggttata
     3781 aaatagaaaa tttacttaaa tttgcaaatg cttgcggtat aagtaatgct ttaaatatgg
     3841 aaactggatt tgtagatttg ggagaaattg ataaatatca agatttagtt gaagtaaaaa
     3901 agttaagtta aataaattta atgggaatat aataaattta atgttgttgt aatagatttt
     3961 aattttaata taaaagatat agtcttatat aaaaataggt tagaaaaatt catttttaac
     4021 ctatttttat aataaatatc tattttactg aatttataat tttctctagt aatctttgag
     4081 ccttgataca ctcttctcca ttaatagctg gttttatatt attttctata caatcaataa
     4141 aatgatttga tatatcctca aaaccctttt gttttaatat atttacccat gcaccacttt
     4201 gttttaaagt taggtttcca ccttcttcta tttccagtac attaagattc ttaactcttt
     4261 gaatcttacc ttttgaaaga atttcaactt gttctaactt tgttccagaa tctctatgca
     4321 tagaggtgtt tacagagaaa tgtttacctt taagtttatg acttacaaat ataagattct
     4381 tattgtctgt taaaaataaa tcttctccgc taatttcaac atcttcattt gctaaccata
     4441 aagcagtgtc aataacatgt atatagtcat ctataagggt actgtcgaat ctaacatttc
     4501 ttaaggaatt taatccatgt ttacatatat tgatagatac gatttctgta gcattatttt
     4561 taatttcttt gtacatagga cagaatctac ggttgaatcc aaccattaaa tttaagtttt
     4621 ttttcttact taactcgata agttcttctc cttgatttac tgttgaagca agaggtttgt
     4681 ctacatatac atgaacacct aaatttaata atatttttat aatttcgtag tgtgtttctg
     4741 tagagctatg tagaaaaata caatcacatt ttttagctag ggattcaata gaatcgaatg
     4801 gcataattct ataatcacta cagatttttt cccttttaac tttatttgga gtaaaagctc
     4861 ctacaaactc aaatctctca gacttagtta atataggtaa atatgccttt tgagctatgg
     4921 agccaagacc tatcattccc atttttatat ttttcataat actttctcct aaggttttta
     4981 tatttacaga attgattata attcagacac ataaatttgt aaactttgta tcaaaaaata
     5041 aatttaaagc ttatataagt aaattaacga aataagaaat attgacaaag taattttgta
     5101 ggatatctat aaaattgatt gatataaata ttttatgtat tgacaaaaaa ttcaaattaa
     5161 tttatatttg gattagtggt aattaccact ttggtctgaa caagttttta tcgtaaaata
     5221 aaaatactaa agtatgattt tattaaattt ttaaagataa actataaaat taattaaaat
     5281 ctatagcgta tattttatag tgagtttaag tagtactaaa aaatctaagc aaaaaattat
     5341 aaaagagtat atttttttat agtttaaagt ggttataacc tcattaccaa atgtaaacgt
     5401 tacaagtatg aaaggagaat gaaaatgttt aaattagaag aacaaaaact aaaagattta
     5461 ggtgcaataa taacaactaa tgaaataaaa caacaacctg agttatggtt agagacttat
     5521 gaaatatata aatctaacaa agaaaaatta aatagattca tagatacaat aagtaataat
     5581 catgggcagt ttagagttat atttacaggt gctggaactt cagcttacat aggaaattca
     5641 atacttcctt accttaagaa taaaaatgac ataagaaaat acatatttga agcaatacct
     5701 actacggata tagtttcaaa cccatatgat tacttaaaaa aagatatacc aacattatta
     5761 atttcatttg caagaagtgg aaatagtcct gaaagtttgg ctgctttaaa tttagggaat
     5821 aagattgtag ataattttta tcatttagct ataacttgta atccgcaagg agaactagct
     5881 aaaatgacta aaaacgacga aaataattac ttgttattaa tgccatcaaa atcaaatgat
     5941 gaaggctttg ctatgacagg aagtttttcg tgtatgatgt tatctgctat gttaatattc
     6001 gatagtttag aagatgatgt agaaaagtca tatataaatg caataattga aatgggaaga
     6061 aatgttatag atagaaaaga tgaaatacat gagttaataa ataaagattt cgatagagtt
     6121 gtatatttag gttcaggagg attaggtggt ttgacacaag aagcacaact aaaactttta
     6181 gaacttacag caggaaaaat atctacggtg tatgattctc ctatggggtt tagacacgga
     6241 ccaaaatcat ttattgatga aaatacactt gtatttgaat ttgtatctaa ctgtttatat
     6301 acaagaaaat atgatttaga tgttttagag gagataaaaa gggataaaat tgctaaattc
     6361 acttgtgcag tgtcagtaga aaatgaaaat aacttctcag gaacaaagtt tgagtttaaa
     6421 gaaaagtata ataaattacc agatgtgtat cttgcaatgc catacatatt gtttgcacaa
     6481 actatagcat tgtttgtatc ggtaaaggtt ggaaataagc cagatacgcc atcagctaca
     6541 ggaacagtaa atagagtagt aaaaggtgta acaatatatg aatattaaaa gataagatta
     6601 aaatattata actaaataat ttgggagggt atcaatgtgg cattagtaac aacaacatca
     6661 atgcttaaaa aggcacaaga tgaggggtat gcagtaggag catttaatgt agaaaatatg
     6721 gaaatggtaa ttgctgttat agaagcagct gaggagttaa actctccagt aatattacaa
     6781 actactccat ctactgtaaa atatgcaggt cttgattatt atctagcaaa tgcaaaggtt
     6841 gctgcagaaa gagtaaagat acctgtagca atgcatctgg accatggttc aagttttgac
     6901 cttgcaatga aagctttaag aagtggatat acatcaataa tgatagatgg ttctcatgaa
     6961 agctttgaaa ataatatatc tatatctaaa tcagtagtaa aagcatgtag tccttctctt
     7021 ataccagtgg aagcagaact tgggaaagtt ggtggaaaag aagatgattt agatggcggg
     7081 aatagtaatg attatacaaa tccaaaagag gcaaaagagt ttgtcgatag aacaggaata
     7141 tcttcattgg ctattgctat aggtactgca catggattgt ataagggtga acctaaaata
     7201 gatttagata ggttatcaga aattaaaaat gtagtttcaa tacctttagt attgcatgga
     7261 ggttcaggaa tacatgatga tattataaaa gaagctataa aaagaggtat tgcaaaagtt
     7321 aactatgcaa ctgaattaag aattgcatat agtaaagggg ttaaaaaagt tttagatgaa
     7381 gattctgagg ttatagaccc taaaaagtat ggattagcag ggcttcaatc agtgaaggat
     7441 tttgtaaaag aaaagattaa agtgtgtggg tctgtaaata gagtataaaa ataaaatatc
     7501 ctaaatttat tttagataag tttaggatat ttgttatatg aaaaatttat attaattata
     7561 tgtaaatggt gtattttttt catttaattg atgaaaaata tcagctttta ttggtaaagt
     7621 attacatata taattaaaat ataataaaaa ttgaactata tattttatta ttataaaata
     7681 tgtatattaa attttggaat caaaatatac taggatataa aattcttaaa taaaaagaaa
     7741 aggttgtttt tataaaaaat attttttata ccactttaaa aaacacaata ataacactga
     7801 gggaggtggg gatatgagag aacgcattat tcttgaaaca ttaaaaaata gtagtggtta
     7861 tctaaacata gattattttg cagataagtt gggggtatct actcgaacta tcagaaatga
     7921 aataaaaaag atagaaacta taaaagaatg taatggtttt aaattagaat ataagtctaa
     7981 attaggatat attctaaata ttaaagacca agataaattc gagcattatc taagaaactt
     8041 accctcagat ttagttgaaa atccagaaca acggttggag tctataatag tagagctttt
     8101 agtaaatgaa ggttataaaa ctatagaaca gttaagtaaa aaatttctag taagttcatc
     8161 ccaaataaaa aatgatttaa aaaagataga tgaaaagata aaggatacag aattaaaact
     8221 agagcgaaag gctcattatg gaattaaaat agaaggttct attaaagaaa ttcaaagtat
     8281 attggtggat agttatttta gagggaatag aaatataaca gagtacagga ataagtttat
     8341 agataattta aaattagcta atattagaag tacaataaaa aatgtactta atgaacatga
     8401 tttagaagca aatttaacag aacttgagga aatattagca caaattatta tattgtatat
     8461 aagagttagt atgagagtag tgggaaatgc tagcaattta aaattatata cagaagattt
     8521 aattatagat aaattattag ataaaatttt tagagataaa aaatataacc ttaattatga
     8581 tgaaaagtat tatttaaagg agcttataaa actaaagact aaagataaga aagccactat
     8641 aaagaatatt gataagaata aacttcaaga tattatgttc gaatttttta gagagataga
     8701 taaaaaatat aactctaatt ttttagaaga taaagagttt tttaacttat tttacttaca
     8761 tattgcatgt ttaatagaac gtataaagaa gaaccacaag ataataaatc ctttttcagt
     8821 taaaataagt caacagtatc caactgtttt taatttatct attcaatttt caaaaatcat
     8881 agaaaatgag tatcatataa aaataagtca agatgaaata gggtttatag ctactcacat
     8941 tgctgttcct tttgaaaaga gagaagaagc taattttaat aaaaaatata aaatagcaat
     9001 aatatgctct tctggtggag gtagtgcatt tttgataaat ttaagactta aagaaatttt
     9061 tccaaatgct gagataagaa atttttcatt actagaagaa aaagctgtaa tagaatttgc
     9121 accagatttg attttttcaa taacaaatct tttatttgaa ataaatgctc cagttatact
     9181 tataaatgaa attttagacg aattggatta tttagatatt aaagaaagtg ttagatttgc
     9241 agaccatata ggaaatatat caagcccaaa acaatatata ttaggtctat ttgataagaa
     9301 tcactttagg tgtataaaag ataaagctaa gtataaggat atccttgata gtatgtcaaa
     9361 atgtatagtt gacgagggag cttgttctcc aacctatccc aaagatgtat gggaaagaga
     9421 aagctatttg agtactattt atacaaatgg ggtggctata cctcatccaa tcgagatgac
     9481 aggaaacaaa aatataatat cagtagcttt gatacaaact gatattattt atgaaaatag
     9541 ggtgcccaaa attattttca tgatttcatt aataaaggga aatttagaac ttcataagca
     9601 aatatctaaa tatttaagta agattatggc aaataaggat atggtagaca tgctaaataa
     9661 gtcacaatct tatgaagagt ttatgtataa gttaaaaatc tatctgggag gttagacatg
     9721 aatatagagt tttttaagag gttgtcagaa gcagatggta tagcatctaa tgaagaagag
     9781 gttagacatg ttttattgga agaactaaag gcttatagtg ataaaattat ctgtgatggg
     9841 ctagggagta tcatcttttc taaaataaaa gatgagagtg caccaaacgt aatgatttgt
     9901 gctcatatgg atgaagttgg atttatggtg agaagtatag acaaacttgg tatgattcac
     9961 ttaataacaa taggaggagt aaaacctctt gcacagtttg tacaaaaagt tagaattaca
    10021 acaaaagaag gaaagaaaat ccctgctgtc ataaatgcta catataataa tggtaaggct
    10081 gaaaatatat atgcagatat tggagcatat acagaagaag atgtatataa cctagggatt
    10141 aatgttgggg atatggtaac atatacaaca agttttgagg aatttacttt accagaccga
    10201 ttagtgggaa aggcttttga tgataggata ggatgttttg tgatgggaga agttttaaaa
    10261 gaacttagga aagaaaatct aaattgtaat attcactttg cggctacaag tagtgaagag
    10321 gttggaataa ggggagcaaa gacatcaaca cagttaataa atccagatat agtatttgta
    10381 atagatgtag catgtgctaa aaatgagttt gtgagagact atacaaatca gaaacaaatt
    10441 gataaaggtg taatgctaat gcatagagat aggactctag tccctagtag aaaaatgata
    10501 gattatgtaa tggaaattgc tgataaaaat aatataccac ttcaacatga tatgtttgaa
    10561 tcaggtggga ctgatggagg agaagcacat ctcgtaaatg aagggaaacc ttgtgtagta
    10621 acttgtgtac cagttagata tggtcattgt gcattttcaa tagtaagtaa taaagattta
    10681 gagaacatta taagattgta tacacagtta attttaaatt ttgatgaaga acaatataaa
    10741 catataagaa attttatcta aaggagaata agaaaatgtc aacagaagta caaataatgg
    10801 agcttatatc aactgcagga gagagtaaat cgaaagcttt tgaggcttta aaaaaagtaa
    10861 agtcaaaaga ttttaaagga gcaaaattgt taatagagga ggctcgtaaa atagatattg
    10921 aggctcacag aatacagaca gaattaataa ctcaagattt aaatgaagat gttgaaagcc
    10981 caacaatgag tcttttaatg gtacatgctc aagaccacta tatgacttct cagctagcaa
    11041 aagacttgat agaggctttg atatattgtc tcgataagta attgtaatgt agaaatagat
    11101 tatttatgta aaaattcttt taaaagttta gatgctttta agagataata aaaatacaaa
    11161 ctttaggagg aattattatg aaaatattat tatgttgtgc aggtggattt tctactaata
    11221 tgttaatgca aaatatgaaa aaggtggtaa aagagagtgc taaactcaat gaaaaagatt
    11281 ttgagtttac agctatacca gcagattcaa tagaaagtga agttgatgat tgggatatag
    11341 tacttatagg tcctcaaata gctcataaaa tagacttctt aaaaggaata ttagagccaa
    11401 aaaataagcc ttttgcagta atagataaag atgtatatgg aaaaatggat ggagctacag
    11461 ttatgaagtt ggcattaata acttataaga aacatcaatt agctcaagga taataaaaat
    11521 aatgagggaa aagggagatt agatatgttt tcaaaatttg aagcatttat gaatagagta
    11581 tttatgcctt tagctcataa ggttgacaat caacgtcacc ttggttctat aaaggctggt
    11641 atggttgcta tgacaccatt cacaatatta ggaagtatat ttgcaatact tccagcactt
    11701 ccaaatatgc ttggagaaaa taatccaata agcaaattca tacttaacaa ttcagcaata
    11761 ttggatttac cagtaagtct ttccataggt ttaataggat tatatgcttg tatgtgtatt
    11821 gcttttaatc tggggaacta ctataaatta tatataccag gttgtgttgc actatcaact
    11881 ttttcttttt tattcctagt agcctcattt acaccagatg gagctttaga aataggaaat
    11941 ttaggagcta aagggctatt tacaggtatg atagcagggc ttggttctgt ggagttatat
    12001 aatttttgta ataagaagaa tatcacaata aaaatgccag aaaatgtacc tgattttgta
    12061 tctaggtctt ttgaattaat acctactact ataatagttt gtggaacttt tatagttgct
    12121 cgttttattt cattaaaagt atttggagaa ttacctccac agatacttac tcaattttta
    12181 tctccattag taggaagtat ggataaccca tggtcagttc ttgcacttaa ctttgctata
    12241 tgtactatat tcttttttgg aatacattca tcagtattta gtcctataac tagacctata
    12301 atgattacat ttatagctga aaacatagca gctatgcaag ctggagaaac aatacctcat
    12361 ttctttacag caggagcttc aagtgcattc tttggattta caggatgtgg aattagtata
    12421 ggttgtgtaa ttgcatgtat gttatcaaaa aatgcttcct ataagaagat tggacgtgta
    12481 tcattattcc ctgcattatt tgggataaat gaaccaatat tatttggagc accgataata
    12541 ttaaatccaa taatgtttat accacatgta tttggtggag ctataatagg tacactacca
    12601 atgtttttta tgcactgggg atggttagca aagccagtat ttgaccctcc atatgtaggg
    12661 gtattcttag aaggattttt aactaatgga gattggcatt ctatattagc aaatgcattg
    12721 caattagtat tagcagtttt attatattgg ccattcttta aaataatgga acgtcaacaa
    12781 aataataaaa aacaaaaaga agaaactaag aatatattct ctaaagaaga agaagactta
    12841 ttggatgatt taggattgga tttctaatat tttgttatga ataatacaat agagagatta
    12901 gtatccttaa tctataaaag aggtgttgac gctcttttga ttaaagcaaa aaatactaaa
    12961 agatatatag gagctttatc aggtagtggt gtatatgtgc ttgttactaa ggataaaaat
    13021 tatcaaattc tagatggcag atatattgat gaagcagata aaaaaacgac tggtttcata
    13081 aaaaggattg tatctcaagg ttcttatata ccaactataa ttgagttatt aaaagaatta
    13141 aatataaaaa agttagcaat agaaaaccaa gctatgagta tacaagagta tctttcacta
    13201 aaaaatgaag gttttgaaat caatttaata acaaatgaat tatggaagct aagggctata
    13261 aaatctaaag aagaaattga acttattaaa aaggcttgtg agattacaga tgaagtattt
    13321 gatgaggtta tttctgaaat taaaaaagat atgactgagc tagaagtatc agctctaatt
    13381 cagtatcatg cattaaaaaa aggtgcaagt ggaatgtctt ttgaaacaat agtggtatca
    13441 ggagaaagag gtgcaatgcc acatggaaga cctacaaaca aaaaattgaa agtgaatgaa
    13501 gctataacaa tagattttgg tgttgtttat caagggtatc aatcagacat gactcgtaca
    13561 atatctatag gtaaacctcc taaaattatt aaagagatat atgatgtagt attggaagca
    13621 caattatctg caatagagtc aataaaggaa ggaactaggg caagtgatgt tgacaaagtg
    13681 gctagaaaaa ttatagataa acatggattt ggcgaatatt ttaatcatgg actgggtcat
    13741 ggtataggtc ttggagatgg tgaagttccc actttaaatc caaatagtga agatatatta
    13801 gtggaaggaa tggtaatgtc ttgtgagcca ggtatttata ttccaaatgt agggggagtt
    13861 agaatagaag atgatattgt tataatagat ggaaaaggtg ttccactcaa taagacatcc
    13921 aaagagttta taatattagg agagtaaaat tatgaaatat aattttaata aagtattaaa
    13981 tcgtaaagaa ggaaattgta gaaaatggag caaccatgtg attaaagaaa aattcggctt
    14041 aaatgaagat gcaattccta tggatttagc tgatatcgat tttgagtgtg ctcctgctat
    14101 aaaagaatct atcttaaaaa gagcatcagt aggagattat agttatactt ttataggaga
    14161 tgacttctat gatgctatta taaattggaa taaaagaaga tttgatgtat atatagaaaa
    14221 ggattggata aaattaactt ttggtactgt ttcaaccctt cattatatag ttcaagcata
    14281 tactaaagaa ggagagggtg tattgataaa tacacctgct tatgaccctt ttgcagaggc
    14341 tgtagcaaat aataatagaa agttgtgttg tagctcatta aaattagata acaatagata
    14401 ttatttagat ttagaggata tggaaaatca aatgaaatac gagaatataa gattacttat
    14461 attctgtagt ccacaaaatc catcaggtcg tatatggaca aaagaagaac tatatcaagt
    14521 gtcagagtta tgtttaaagt ataatgtaat tttggtaagt gatgaaattc atagagatat
    14581 aatatttaaa gattatagat ttgtatcttt gtggaatgct catccagaaa tttataaaaa
    14641 tagtataatc tgcgtatctc ctaataaagg cttcaactta ggtggattaa aaacatcata
    14701 tgtattaata agagatgtaa aaattaggga gactttatta gaaaggctaa aaagtaattc
    14761 aataacttct ccaaatgtat ttgcaatacc agcaatagtt gcagcataca atgaaagcga
    14821 agaatggcta gatgctatga ctagttatgt agaggagaat tttgaaatag tttatgattt
    14881 ctttgaaact aatataccaa aagccaaagt gatgaagtca gactcttctt ttttagcctg
    14941 gatagatgta agagaagtat ttagaaatga agaagaatct aaagaatttt ttagacatgc
    15001 aaacttaact atggtagttg gaagttattt tgtgaaagat ggagatggat ttattcgtat
    15061 taatgtgggg tgtcctagag aaacattaaa tgaggctcta aatagaatca aaaaaacgta
    15121 tataagtatg tattgttaaa tcataaaaaa agtatctatg gtttatataa aaacacatta
    15181 tttagttatc aaatattact ggaattttgt attccagtaa tattttttga ttaaggaata
    15241 ttattgagga atattaaata atattatttc atacccttat attaacttat ataaaaatat
    15301 tttattattt tgggaacggg ttagctaacc tttatctagt gtatatttat attgtaagaa
    15361 gcagtaaaaa cttttccctt actaagttta ttaataaact tcttatcttt ataaattttg
    15421 ttagaattta tactatcagc aagaccatac caaggttcta tacataaaaa aggagcagta
    15481 gaattagttt cactataata aggagtccaa ataccaacta gagggaaatc ttccatagat
    15541 atagttacat atttactacc atcattatta tatatagaca cttcatctat gttggtgtat
    15601 atcaaagcat cattcttgaa tacttctgga tttaaatgta agttttttaa ttttccaata
    15661 ggtattatat catctgtaaa agaaccattt aaattgattt tttctacatc atttttactt
    15721 ttaaactcaa ggtagtgttt agaaaaatca ttttgtttgt aaaaaggaag gttgaatgca
    15781 ggatgtccac ctatagaaaa gaatatatct ttagagtcag tattttttac aatccattct
    15841 acctcaatac tattatcatt taatgtatag tttatgatta gctcaaaaga atatggatac
    15901 ttctttaaag tggattcatt atctgttaat ttataagata caaatgtatc tcctttatct
    15961 acaatctcaa agtccatatc tctagcaaac ccatgttgag tcatgctata taaattttct
    16021 tctattattg tttcattatc aaaaagttta cctactatag ggaacaatat aggtgattgt
    16081 ctaccccaat attttttatt accatcccaa agaatgtttt tgtcgtattt tttagaaaat
    16141 attttagtta gttcagcacc aaaactgctt gattcgataa ttaaattttc attttgtaat
    16201 atattcattt aaaatctcct ttattatatt ttatgagtat attatactat aaagtataaa
    16261 gattattaaa ttttatttga tattatattt gaaaggtaga ttttagtata ttttgaaaat
    16321 tttgttttga aaatttggga ttatttaaga aattttgtat tataaataga aggaaataga
    16381 taaattgtat agaataaaat atattaagat aagttaataa tgttaaatgg gaagtgagtt
    16441 tatggaaaaa ccaaatacaa aagttgttaa ctttcaagag tataaagaca gaaaaaacca
    16501 aagagaagta aatagagacg aacttttaaa gcttataaaa aaaattgtga cttcaaaata
    16561 gggagttgtt aaactcccta ttttaatggg tttcataata attaagacat tctgagtcca
    16621 tctatataat ctttgaattg tgagaaatct gattcactac ttaattctat ggtttctgaa
    16681 ccttccgtat aaaaattctt aagatagata gtataattat tatcaacaca atcatgataa
    16741 atacatctat atccatcttc atacaaactt tttaacttag aaaaatcatc cacaatatca
    16801 tctccttaaa gttcttttaa atatattttt acaaaaagca tctaattgta tgcaaattga
    16861 caatgtaaaa taaaggaaat gaacataaaa tgtagaataa tttttatatg tatgtaaaaa
    16921 taaaaagaaa aagttgaaat ttttagaaaa taagagtatt ttttatctaa aaagagagtt
    16981 taaaaaataa aaaaatgttg ggaggataaa aaatgagttt attagaaagt atatcaaaaa
    17041 acatatattc cctagataac tcttctattg aaaaaacaaa gcagagattg gataggctta
    17101 tacatccaac tggaagctta ggaaagatag aagatatttg catgcaattg gcaggaatat
    17161 ttggcaatga aaattttgac acaagtaaaa aggttataat tgcttttgcg ggagaccatg
    17221 gtgtatatga agaaggcgta gcacctgacc ctcaaaatat aacaaaatta cagtttccaa
    17281 atttttcgaa aggtctatgt ggagttggag taataagtaa atttgtaggg gcagatgttg
    17341 tagctgtaga tgtaggaata aactgtgatg aaaaactgga tggggtatta gactacaaga
    17401 taagaaaagg gacatcaaat atggcaaaag gtccagctat gagtaaacaa gaagccatta
    17461 gatgtttaga gataggtatt gaaatagcag agcagtgtat agaaaaagat tataaggtta
    17521 ttggtattgg ggagatgggt atagcaaata ctactccaag tacagcaata atatctgtaa
    17581 tttcagggtg tgacccgtta gaagttactg gtataggtgc aggtcttaag aaagaaagac
    17641 taaagcataa ggctgaagta attagaaagg ctattgaaat taataatcca aatccaactg
    17701 atggagtaga tattttatct aaagtaggag gatttgaaat aggctcaatg gcaggtgtta
    17761 tattaggttg tagtgctaat aggattccag tagtaattga tgggtttatt tcttatgcag
    17821 cagcattaat tgcatataag ataaatccaa aaactagaga atatatgata gcatctcatt
    17881 tatcagcaga atcaggaact aaaagagcat tagacatatt aaaattagac cctctattaa
    17941 atatggatat gagattaggt gagggaagtg gagctgcttt agcatttgat ataatagaag
    18001 cttcaaacta tacttacaaa aatatggcaa cttttgatga aattgacatg ggaagataaa
    18061 tataaaaatt taatatgtag gagtgttttg atgagtaaaa ttattctagt aacaggagga
    18121 gctaggtcag ggaagagtaa ctttgcagaa aaactatgtt ttgacagaaa taataataca
    18181 gcttatatag caacctctat tccatttgat gatgaaatga aagatagagt aaaaaaacat
    18241 caagagaata gacctagaaa ctggaatact tatgaaatat atgaagatat atattccata
    18301 attaaggaga tatataaaga acatgaaact gttatactag attgtgtaac attattagta
    18361 aataatctaa tgtttgaaca caatctaaat atagaagagt ctagtcaaga agaaataaac
    18421 aaattagaac aatacataaa agaacaagtt gtcaaactta ttgaagaaat agaaaaaaca
    18481 aatctatact ttgtatttgt aacgaatgag ttaggtatgg gaattgttcc tgggaataaa
    18541 cttagtagaa tttatgctga tattgtaggt cgtataaatc aatatatagc ttcgaaaagt
    18601 aatgaagttt attttgtagt tagtggcata gctatgaaga taaaggagta gtatgcaatt
    18661 atgaaaagat ttattttaat actacagttt ttgacaagga tacctataaa attaaatgta
    18721 ggatttgatg atgaatttta taagtcaata gtatattttc cacttgtagg ttttgtcata
    18781 ggtatattat cctatttaat aggatggatt tctatgcttt tatttgaacc atttatagct
    18841 tctataataa taactctagc tggtgtctta attactggag gacttcatat agatggatta
    18901 ggagatacat ttgatgcaat atatagttat agggataaag aaaaaatgct tgaaataatg
    18961 aaagattcaa gattaggtac aaattcactt ctagcaatta tgtttgtact tttattaaag
    19021 gttggattcg tttacgatat aataagtaat aattcattgt ggattataat ttttatgcca
    19081 atgattgcaa ggttaggagt aatgttattg acatataaaa ccgtgacacc aagagaaaaa
    19141 ggaatgggaa atttatttat aggaaaatta actacaagta tgttaataac tgctataata
    19201 tacacattat tgatagttgc tcttattact aaatttatat ttttattacc taatatagtg
    19261 ttgattaaag tattaggttc gattatagtg gtttttgtat ttataatatt attcaaaaaa
    19321 catatttata aaaaaattga cggagtaaca ggagatatat taggctgtgg aatagaactt
    19381 tcagagcttg tatatttaat ttacatatat ttgttaattt ttatgttttt ttaaagtaaa
    19441 aagtggtgat aatatgataa gattaatatt aataagacat gcactgacaa atgataataa
    19501 aaaaggaaga ttatcaggcc atataaatag ttgtattagt gaagagggca aactacaaat
    19561 aaataaaatt accagatatc tgagtaatga aaacatagat aaggtttata caacaccatc
    19621 tacacgtact aaagatacag tagaaaaaat atcaaaattg aaattattag aaatagaaga
    19681 aaaagaagct ttaagagaaa ttagttttgg agactttgaa ggaagaactt ttgaagaaat
    19741 taaaatcaaa tatccaaatg agtttgaaaa aatgataaaa gaaggtaaca actatagata
    19801 tccaaatgga gaaagtttga tagactctta taaaagagtg gcaaaagaaa ttgataatat
    19861 aattttagaa aatgatagta atttagatac aaagacaata cttatatgtt ctcatgcagg
    19921 aacaataaga aatataataa cacatttgat ttctggtagt tataagtatc actggaactt
    19981 taaaattgat aatgcatcta ttacagtttt agaaattgat ggtggatttg ctgtaataga
    20041 taaaatgaat tttacagact tcatataatt taatcaaaac caaacattac aatctgtgtt
    20101 tgtaatatat ctgtaaaatt agcaatgaaa atagaatatt agattaaaat taggttctta
    20161 attagatgtt aaaagggaaa aaggttagat gcctttgcag cccccgctac tgtgaaacca
    20221 acgaaactat aaataccact gtcagtttga tgggaaggtt atagaagtag gatgaagtta
    20281 agccaggata cctgcctaat ttaatttaaa acaagaggtc ttcggggtga aagattttta
    20341 attaatatat ataaaagtcc tatctttaga agtattagga ctttttttaa tttgtttttt
    20401 agtaaatttt aacaaggagg gatggaaagt ggggaaaaaa ataatgctac aaggaacagc
    20461 ttcaaatgta ggtaaaagtg tcttagtagc aggtttgtgt agaatattta agcaagatgg
    20521 ttatactgtt gctcctttta agtcacaaaa tatggcttta aattctttta taactaaaga
    20581 aggattagaa atgggaagag cacaagtatt tcaagcagag gctgcgaaaa tagagccaat
    20641 agctgatatg aatccagttt tattaaaacc ttctgggaat aataaaagtc aagttattgt
    20701 aagaggtaaa gttgtaggag aaatgccttc ttctaagtat catgattata aattggagtt
    20761 agtaggtgtg ttgaaggaaa catttaatag cttaaattca aggtatgata ttgtagttat
    20821 ggaaggggca ggaagtaatg cagagataaa cttaaaagat agagatatct ctaatatggg
    20881 tatggcagaa atagctgatg cacctgtaat aatagtcgga gatattgata gaggaggcgt
    20941 atttgcctca ttagcaggaa caatgctttt attaaatgaa gatgagaaaa gaagagtaaa
    21001 aggtgtaata atcaataaat tcagaggaaa aaaagagctt ttacaagatg gtgtaaagat
    21061 gctagaagac atcataaaag tacctgttat aggagtagta ccttatacag atataaaaat
    21121 agaagatgaa gacagtgtaa ctacgagatt taagaaaaaa atgaataaaa gtgatataca
    21181 catagaaata attagaaccc cacatatgtc aaattttaca gattttaata tatttgagac
    21241 acaagaagat gtaagtatta gatatgtaga ctatggagaa tctttaggaa atccagatat
    21301 attaataata cctggaacta aaagtactat agacgattta acatatataa gaaaaagtgg
    21361 tcttgaatcg caaatcaaaa atttacatag tcaaggtaaa ttgatatttg ggatatgtgg
    21421 tggataccaa atgttaggta aaaaattaaa agacccttat catgttgaaa gtgaaattga
    21481 agaagttgat ggaataggtc ttttagatac agaaacaacg tttgagaaag aaaagactac
    21541 aacacaagta gaggctacta ttgttgaatg tatcagtgaa tacatgaata accttaaggg
    21601 aaaaaaagta aaaggttatg aaattcatat gggcattaca aagcgaggta atgatgtaag
    21661 aagtttagat ttaataacta aaaaacttga taaagaagtg aattatactg aaggaagtgt
    21721 aaataaagag gggaatgtaa ttgggactta tcttcatgga atatttgatg aaataagctt
    21781 tacaagagca attttaaaca atataagaaa gaaaaaaggt ttaggagaat tagaaagcaa
    21841 agtaaactct tttaatgaat ttaaggataa agagtatgat aagttggctg attttttaag
    21901 agaacattta gatatagaga aaatatatga gattatgaaa taatgatgac ctttatttat
    21961 aatttaggta ggaggtgtat tatgaaaaaa attttaattg ctggtactaa tagtggagta
    22021 ggtaaaacaa caatatcatt aggaataatg caagctttgg ttaagagaaa tatgaaagta
    22081 cagccatata aagtagggcc agactatata gacccttcat atcacacttt tataactgga
    22141 agacattcta gaaatttaga ttcttatatg ttagatgatg aaaaaataaa gtatatagta
    22201 aataagtcct caaaagatgc agatatttca gtaatagaag gtgttatggg cttatatgat
    22261 ggttttggaa tagatttaga taattgtaca agttcacata cttcaaaggt attaaagtca
    22321 cctgttatat tagttataaa tggtaaatct atggcagcat ctagtgctgc tatggtactt
    22381 ggatataagg aattagataa agatgtaaat ataaagggtg ttatagtaaa taatgtaaag
    22441 actaatagcc attatcaaat aattaagagt tctatagaaa aatattgtaa tgttgaagta
    22501 ttggggtatt ttcctccaaa taacaaattc tctttagaat ctcgacatct aggattagtt
    22561 cctagtgtag aaatgaaatc actaagggaa aaattttata ccttagcaga tgaaattgaa
    22621 cactatatag atattgacag aataattgaa atatcagaaa gcgatgaatt tgagagtgat
    22681 tttgattttc aaactttgat agaaaataat aaaataaaag aacatgttaa taataaatca
    22741 atagctatag catatgataa agcattcaat ttttattata gagaaaatat agagctttta
    22801 gaggaacttg gtttagaaat aaactatttt agccctcttg aagatgcatc agtgccaaat
    22861 gcagattata tttatattgg aggaggtttt ccagaaatat ttggaaaaga attagaagca
    22921 aatgagtcaa tgagaacttc catattagaa gcacataaca ataatatacc tatttatgca
    22981 gaatgtggag gactgatgta cctaggtgag aaactattga atcaagaaga acaagaattt
    23041 aatatggttg gaatatttag tggaattagt aagatgacat cttctttaaa gagatttggg
    23101 tactgtattg gtgtagccaa ggaaaatact cttttatcta aaaaagggga atctattaaa
    23161 gggcatgagt ttcatcattc aatatttgaa agtgatgaaa aatgtgtata ttcaatgaga
    23221 aaagaaagag atggaaatat agtagaagag tgggatggtg gttatagtaa aggaaacact
    23281 ttggctacat atcttcatac tcatttttat aataacttaa attgtataga aaattttttg
    23341 aaaaaaggaa atgaataaat gagtatttta tctatttata taggatatgt gacagactta
    23401 attgtaggag acccatattc ttttcctcat ccagtgagat ttattggtaa acttataaat
    23461 tttactcaag gtataataag aaaggtctct aaaaatgata ggcagttaaa atttggggga
    23521 tttatattat ggtttataac cgttggaata acatatttaa caacttatgc tatagtgaag
    23581 ctatttagtt ttaatatatt attgagtatt gtagtgaata gttttataat ttatacaaca
    23641 ctagccacaa aatgtttaaa agacgaagca ttaaaaattt ataatgtatt aaaaaccgaa
    23701 gatatagaaa aatctaggat tcagctatct tatatagtag gtagggatac tactaattta
    23761 agtgaacctg aaataataag agcaactgta gaaactgttg cagaaaatac tgtagatggt
    23821 ataattgcgc ctatgtttta tgcatttatt ggaggagcac cacttgctat ggcctataaa
    23881 gctataaata cattagactc aacagttgga tataaaaata aaaagtataa agatattggt
    23941 tttgcatctg ctaagattga tgatatagcc aattatatac cagctagaat atctgttatt
    24001 cttatgacaa ttggaagttt ctttttaaat tataactata ggaactgttt taaaatctct
    24061 attagagata gaaagaatca taaaagtcca aattgtgctt tttcagaagg cgcagtatct
    24121 ggtgctctag gaatacaact aggaggtacc aacgtttatt ttggggaaaa agtatataag
    24181 ccaacaatag gggataagct tagggagata gataaagaag atataattaa aactaataaa
    24241 attatgtatg tatcttcatt tgtatctatg ttggtattta cactaataca tgtgttatgt
    24301 aggatgattt taattaactt aattatataa attattgttt gctaacttaa gggggacata
    24361 gatgaaggat ttagggcatg gtgccaatgt aggtgaaatg gcaagattat atgggaaaaa
    24421 cccaaaagaa ataattgatt ttagttcaaa cataaatcca aatgtattac caaatttaga
    24481 gagatacatt ttaaaaggat tagaagagtg taggaattat ccagatataa attatacaaa
    24541 cttgagagaa aatatatcaa aatatatagg tataaatcca gactttataa tacctggaaa
    24601 tggtgcaaca gaagtgattt atttgcttat gaagagtgtt aaaaaaaaat tggctataat
    24661 aaatccgact ttttcagagt atagaagaag tgctgagtta aataatttag atattataga
    24721 tttagagcta gatttagaaa ataactttaa acttaatata gatataataa aagaaaatat
    24781 aaaaagattt gatagtttat ttatatgtaa tcctaataat cctagtggta atgtccaaga
    24841 tttaaaggaa cttgttcatt tactaggtaa acataataag gtactaataa ttgatgaaac
    24901 tttcatggaa tttgttgaag atgaaagtaa atacagtttg gttaaatata tagaatcaaa
    24961 taaaaatata tttataatta aagctgtgac taagtttttt ggtatgcctg gtttaaggct
    25021 aggatatggt cttacaagca acactgaaat tatgaacaaa atttatgaac acaaagagcc
    25081 atggactatt aattcttttg cagatatact atccaatttt atttttgaag ataaagagta
    25141 tattaaaaat agtaaagaat attacataga agaaagaaaa tatatgttac aagagttgag
    25201 aaacataaga aatataaagg tctatgatac agatgctaat tttattttga taagagcata
    25261 taaaaaaaca actaaagaat tgaaaaaaga tttgcttaag caaggaaaca tattagttag
    25321 agatgcgtct aattttatag gattagatga tagttttata agagtggcta taaaatctca
    25381 tgaagataac aaaattctta tagaaaatat gaaaaattta ttgggtgatt aaaatgaaat
    25441 cttatggaat atgcccagca tcttgtggag aatttgtaca aggtataatt gatgatgaag
    25501 aatatttatg ttcatatgca atagatatgt attctgaagt gtatattgaa gaaaaattag
    25561 tagatataaa tttagggaga tataagtcaa ggttagcaat tgaaaaggta tttgaaaaat
    25621 ttaatttacc taaaaaatat actaaaaata tttctttaaa tataaatagt aaaatacctg
    25681 ttggaaaagg aatggcaagt tcaactgctg atataggagc tacaataaag gcaacattat
    25741 cattgataga taaagattta agtagtgagg agatttctaa attagcagca gaaatagaac
    25801 caacagattc tatatttata gataaaaata gtatatttaa tcctctaaat ggaactgtta
    25861 taaaatacct aggaaatctg accaatgcga aagttataat acttgaacca aacaaagtac
    25921 tagatactat gaaaattaga ttgaggcaag attataataa attaaaagta gaaaataaag
    25981 aagtaataaa aaaatcattt gctcttttag aagaaggatt gaaaaaaaat aatttatctc
    26041 tagttggaga ggcttgtact ttgagtagct tagcaaatga gaatatagaa aaaaaagagt
    26101 atttaaatga aataataaaa atatcaaaaa aatatggagc atatggagta aatattgctc
    26161 acagtggaac tgtagtaggt attttaattg ataagtctat gaatgataaa aagatgatag
    26221 ataccttatg tgaatctaac ataaattctg tctataataa aatttataca caaaacataa
    26281 ttaatggagg aattaagggg gaaatagaat ggaatacata aagaatccta tgaaaataga
    26341 agaaaaaagt tttgaattga tacaagaaat aatagacgaa attagaccag attataaatt
    26401 taagaataat attgaagaaa aaataataaa aagagctata catactactg ctgattttga
    26461 ttacttagat atattaaaaa tatcagaaga agcagttgat agtataatag atgcattaaa
    26521 aaataatgca agtatttata ctgatacaaa tatggctctt agtggtataa ataaaagaaa
    26581 gttagaatca ttaggatgta agtataaatg tttagtggca gatgatgaaa ctgtaaaatt
    26641 agctaaagaa aaaggaatta ctcgttctat ggcagcagta gaaattgcag ctaaagaaga
    26701 aggaagaaaa atattcgttt taggtaatgc tccaacagct ttatataaag ttatggagat
    26761 gaaatcagaa ggtagattag atttagatgc agttatagga gttcctgtag gttttgtagg
    26821 agcacaagaa tcaaaagatg aagttgaaaa aacagatata ccatatataa tttctaaagg
    26881 tagaaaaggt ggcagtaatt tagcagcagc aatagtaaat gctatattat atactatgta
    26941 ggtacctata tggaagaata tgtatatata gatggaaaaa aatatagaag aggatatact
    27001 acaggttcat gtgcaacagg tgcatctaag gctgctgtat atatgttgat tacaaaaaat
    27061 agaatcaata ctataaatat agatactcct aaggggatac cattactact aaaagttgat
    27121 aatataaata tttctgatac atttgtggaa tgttccataa aaaaagatgg tggagatgat
    27181 atagatgcaa ctcataccat ggatatttat gcaagagctg aaattgtagc taaaaatgat
    27241 aagaacaaag ggtatcttac tctaaaggat atagatagtt taagcaccaa tagtgagtgt
    27301 aaaagtgagc tctataagtt tattagggtt tatggcggaa ctggtattgg tgtggttacg
    27361 aaaaaagggc ttagtgtgga tgttggtaaa cctgctataa atccgactcc acttaaaatg
    27421 ataaaccatg aaataagaaa gcttatagga gataattttg aatctatact tggaaatgat
    27481 aaagttttaa aaataacaat ctttgctcca caaggagaaa ctgtagcaaa aaaaacattt
    27541 aatccaagat taggtatagt tggaggaata tctataatag gtacaactgg gattgttgaa
    27601 cctatgagtg atgagggttg gaagaagtct ctttctatag aacttcagat gaaaaaagaa
    27661 caaggcttag ataaaataat attggttcca ggaaatcatg gagaacagtt tataagagaa
    27721 aaattaaact tagatattaa gtatgtagtt agggtaagta attttatagg ctatatgatt
    27781 aaagaagctc aaagaatagg atataaaaaa atcttaatgg caggtcatat aggtaaattt
    27841 ataaaagtat ctgctggtat ttttaatact catagtaagg tagcagatgc tagaagtgag
    27901 atattagtgg caaacttagc tttaatggga gctagatacg aatttttaaa taaaataaat
    27961 caatgcgtaa ctactgaaga agctgtagag ctaataaata atagtgaata tagagaagta
    28021 tataatatat taagtaataa atgtaaggag agagtaaagc aatacttgaa tgaagattca
    28081 gatgatattg atgtggaagt aatcatattt tcaatggata agtctttatt aggtaaatcg
    28141 gataatacag atgatttagt ggaggtcttt atatgataaa cataataggt ctaggacctg
    28201 gtaacttaga ctatataaca aaaaaaggtg aaaatttaat ttccacttct gatgtattaa
    28261 ttggtggtaa aagaaatcta gagtctataa aaaattttga aggagaaaaa atagttctgg
    28321 attctaattt aagagaaatt atagagtaca taaataacaa taaagaaaag caaatatcaa
    28381 taatagcatc tggggaccca ttaatatatg ggataggtag atatctatct aaaaatattg
    28441 ataataagat gttaaacgtg gtttctggga ttagttcatt acagtacata ttttcaaaaa
    28501 tatatgtaga tatgaatgat gtatatatta caagtagtca tggcaaaata ccagattttg
    28561 attacatatt atcacataaa aaagtatgta tggttacaga ttcaaagata ggaccaaaac
    28621 aaataagtag agaaataata gatagaaatc taaataaaat tattgttgta ggagaaaatc
    28681 tgtcatatga caatgaaaaa ataacaatag cgaaaccaga agagataata agaatggaca
    28741 attttgatat gaatgttgtg gtgattttag atgaggaata gtgaatttat aacaggtaaa
    28801 gttccaatta ctaaggaaga ggttagagca atatcaataa gtaagttaaa tttagtaaat
    28861 gctaaaaacc tcatagacat aggggctggt acaggaagtg taagtgttga agctgcatat
    28921 aattatccta atttaaaggt tatatctata gagaaaaatg atgacgctat agagcttata
    28981 gagaaaaata taaaaaaatt caacttaaaa aatatagaag tgataaaagg atatgctcca
    29041 attaatctag ggttaaatgt taaagttgag tctatttttc ttgggggaac aggaaataat
    29101 ctggaagaaa taatagaatg gtctaaaaaa aatctcgtta caggaggaag acttgtagct
    29161 aattttataa taatagatac atttaatcaa actttaaaac tgcttaaaaa gcatggattt
    29221 aaagaaatag atgtatgtgt tttgaatgtt tctaaactag agaaactagg aaaaggtgaa
    29281 tattttaaac cactaaatcc tatatatata atatcttgtg aaaaagggga aaatgatgat
    29341 gaataaagta cattttgtag gagcaggacc tggagataaa gagctgataa cattaaaagg
    29401 atacaaatta ttaagtaatg cagatgtagt gatatatgca ggttcacttg ttaatcctga
    29461 acttttggaa tactgtaaag aagattgcca aatacataat agtgcacata tggatttaca
    29521 agagataata gatgttatga gagaaggtat agaaaataat aaatctgttg taagactgca
    29581 aacaggtgat ttttctatat atggttcaat tagagaacaa gtggaagatt taaataaatt
    29641 gaatatagat tatgactgta ctcctggagt aagttctttt ttaggggcag catcatcttt
    29701 aggggttgaa tatacagttc cagaaatttc tcaaagtgta attataacaa gaatggaagg
    29761 cagaactccg gttccagaga aagaatcaat acaatcatat gctaagcatc agacatctat
    29821 ggtaatattt ttatctgttc aagaaattga gaaagttgtg tctaaattac tggaaggtgg
    29881 atatccaaaa gatactccta tagcagttat atacaaagca acttgggcag atgaaaaaat
    29941 agttaaagga actttaagtg atatagctgt aaaagttaaa gaaaacaaca taaataagac
    30001 tgctttaata atggttggga gatttttagg agaagagtat aataattcaa agttatatga
    30061 taaggatttc aaacatgaat atagagggta atattgctat aatctgtatt acagaaaatg
    30121 gaaaaaattt agctgtaaag ataaattctc tagtaaataa ctgtgttata tatcaagtaa
    30181 aaaataaaaa aagtaattta gttgttgaag aaacatgtgt acatacagtt caaaagaagt
    30241 taagtgattt tgtaggagaa atatttagca aatttgatta cataatattt ataatggcta
    30301 caggtatagt tgtacgaagt atagcaccat acataataag taagtttagt gaccctgcaa
    30361 ttttggtaat ggatgaaaaa ggcaaaaacg taataagttt attgagtggt catattggag
    30421 gggcaaacag cttgacacag tacataagta gtcttattga tgctaatcca gtaataacaa
    30481 cagctactga tataaatcaa aaagcttcct tagatatgat agcaaaaaaa ctaaatgcac
    30541 atattgataa ttttagagaa agtgtaaaag aagtaaattc tatgctagtg aataataaat
    30601 gtgttggatt atatgttgat gaaggatatc aagttgatac taggggattt aaacttatag
    30661 aaagtaagga tgagttaaga gatagctttt caaacacata tatagaaaaa ttagttgtag
    30721 taagcaataa aataaattgt attgaagata ttgagaattt aaacttagat aataaatttg
    30781 aacattgcta tagtactaaa aaaataataa aggtaattcc aagagatata gtgataggaa
    30841 ttggctgtag aagaaacaca gatagtgagc tgatgtataa ttcacttgaa gagtttctta
    30901 ataaacaaaa tatagatatt agagcaataa acacagttgg aagtatagaa ctgaaaaaag
    30961 acgaaaaagc aataattgaa ttatcaaaaa tactaaaagt gccatttaaa acattttcaa
    31021 tagatgaaat atctaaggtt gataatcttt ttgataaatc tgattttgtt aaaaaaaatg
    31081 tgggcgtgta ttcagtagca gaacctatag catatctttt gagcaaaggt aatttgttag
    31141 ttgaaaaaca taaatataaa ggaataactt tttcagtggg gagaataaaa atatgatata
    31201 cgttgtagga attggaccag gaagtaaaga tacaatgact ttagaagcaa taaaagcaat
    31261 agaagattct gaggctattg ttggatataa gacttatata aaactaatag aagaatttat
    31321 acaaggtaaa gaaataatcc aaaatggtat gaggcaagaa gttgatagat gtaaacaagc
    31381 agtagaggaa gcgaaaaaag gaaaaaaagt agcagttgta agcagtggtg atgctggaat
    31441 atatgggatg gcaggtctca ttttagaatt aatatctaaa gaagatgaag atataaaagt
    31501 aaaggtaatt ccaggtgtta ctgcaagtat tggtgcagca gctatacttg gagctcctat
    31561 tatgcatgat ttctgtcata taagtttgag tgatttaatg actccgtggg aagtaattga
    31621 aaaaagattg agattggctg ctgaagccga ttttgtaatt tgtttgtata atccaagaag
    31681 taagggaaga agtgaacatc taagcaaagc atttaaaata atgggtgagt ttaaaggtgg
    31741 agatacacct gttggagtgg taaaagatgt aggtagagaa aaagaagaaa agtttgtatg
    31801 tacttttgaa aatatggact ttgaaaaagt cgatatgact acaatggtta taataggaaa
    31861 taagtctacc tatattaatg gtgaattgat gataactcca agaggttata cagtatgatt
    31921 ttaattttag gaggaacttc agatagttta tctatatgtg ataagataaa tgaactgaaa
    31981 aatcaaccat atatcctttc agttactaca gattatggaa gggaacttgc acaacaacat
    32041 gcagagaatg taattttagg taagcttgga aaagaagata tgctaaaatt tataaaagat
    32101 aataatatag taaaaataat agatgccact catccttatg cagttgaagt atccaaaact
    32161 gctattactt gtgcaaaatt attgaatata gattatataa ggtttgagag aaaatcttta
    32221 attgaagaaa tagattatga taataaattt atagtagata caattgaaga agcctgtgaa
    32281 atagcaaata aaatagggac aaatatattc ataggaacag gaagtaaaaa tttgaacaga
    32341 tttatagagg aaataagtga taaaaattta gttgttagag ttcttccaac gagtgaagtc
    32401 atattaagtt gtgaaaaatt aggtttaagt gcagataata tagtagctat gaaaggtcca
    32461 tttagccagt atataaatga agaaacatat aaacattaca atatagattt agtcataaca
    32521 aaagaaagtg gaatagctgg tgggttctta gagaaggtaa atgcatgtaa aactttcaat
    32581 ataccagtaa taattataaa aagagaatcg attaactacg aaaatgtatt taatgacata
    32641 aataaaatta aagacatact tgtgtaattt ttaggaggag aatatatgaa gaaagcctta
    32701 ttagtagtga gttttggtac aagctatcat gaaacgagag aaaagacaat agatatatgt
    32761 gaagataaaa taaaaaattc gttaaaaagc catgattttt ttagagctta tacatcaaat
    32821 atgataataa ataaaataaa aaaaagggat ggaatagaaa tagataatcc aatacaggct
    32881 ttagataaaa tatatgaaca aggatatgat gaagtaataa tccaaacact tcatattata
    32941 tgtggcgaag aatttaacaa attaaaagaa caagtagatg gatattcttc taaattcaaa
    33001 aagattgtat taggaagacc tttgcttaca catattgaag attatcagga agctgtagag
    33061 gcaattaagc atcaaattcc tcatatggaa agtaatgaag cagtagtatt tatgggacat
    33121 ggaacacttc atgaatcaca ttcagcgtat ccagcattgg aatacatgct tagggataat
    33181 ggaataaatg cttatgttgg tacagttgaa gggtatccag aaatagaaca tgtaataaga
    33241 agattaaaag aaggaaatat aaaaactgta aatttgatgc catttatgtt agttgcagga
    33301 gaccatgcta taaatgatat ggcaggagat gaagaagatt cttggaaaac aatattagaa
    33361 gaagatggat ttgacgtaag agttcattta aaaggactag gagaaaattc ttatatacaa
    33421 gataaatttg ttcgtcatgc tgtaaaatgt gcagagaatg ctaagttcta tggtatagga
    33481 gcagggccag gagatggttc tttacttacg ataaaagcgg ttaatacttt aaagaaactg
    33541 gatattctat acactccaga atcaaaaaag ggtggagata gtctagcttt atcaatagtt
    33601 agtgaatatt tacctgaatc agtggaaata aagtctaggc atttcccaat gagttttgat
    33661 gggaatgaaa aaagtttagc ttgggacaat gtagcacaag aaattatatc agatgttaat
    33721 gatggtaaaa atgtaggatt tgttacatta ggagacccta tgatttatag tacatatgta
    33781 tatataatga aaagaatatt aggagaggta gaagtcgaaa ctataccagg aatttcatca
    33841 ttttccaata tagcatctaa tcagaatttt ccattagtca tggataaaga agctttagtg
    33901 gtaattcctt gtactatgga agatgataag atagagtatg ctttgcaaaa ttataattca
    33961 atagtattga tgaaggtata taaaaatttt aaagaaataa taaaaaaatt agaaaagtat
    34021 gatttaatag aacatgctat tttagtaagt aattcttccc aagaaagcga aaatgtgttt
    34081 acagatttaa aagaagcgca ccttgaagat aagatatctt atttttctac tatactagta
    34141 aataaagata ataaaataaa ataggtgaaa gcaatattta aaggagactt aatatgaata
    34201 tagtggttgg aactaggggt agtactctag cgcttataca aacagagtgg gtaataaatg
    34261 aattaaaaaa gaagtatcca gaaattagtt ttgagattaa aatcataaag acaaaaggag
    34321 atttaattca aaatgtttca ctggataaaa taggtgataa aggattgttt gtcaaagaaa
    34381 tagagcaaca attattagat ggaaaaatag acatagcagt acatagtatg aaagatatgc
    34441 cttcttattt agcagatgga ctaaaatttg ctcatacgcc taagagagaa gacccaagag
    34501 atgttctaat acttagagaa ggatataaaa atttagatga tttgcctcat ggagcagtaa
    34561 taggaacagg aagtaaaaga aggaagtttc aattattgaa acaaagacct gatttaaata
    34621 tagtacaagt tagaggtaat gtggaaacta ggatacgaaa aataaaagat gaaaacatgc
    34681 atggtattgt gttggcagca tcaggaataa ttagagctaa tttgcaagat aaaataagtt
    34741 cttatttacc tgttgatgtt gttattccag cacctgccca aggagcttta gctatagaaa
    34801 ttagaagcaa tgatagtacg atagagggaa tagtaaattc actgaaggat gagaatacag
    34861 aaatccaaat attggctgaa agaggttttt tagatggtgt aaatggaagt tgtcatattc
    34921 caatggcagc ttattgtgaa ataatccaag ataaaataca tcttactggc ttatatggag
    34981 attcagaagg aaaaaaagta gtaatcaagt ctatagatgg agatatttct tctcctagag
    35041 agttaggttt aaagttagct aaacttgtat tgaaggagta tgagaattat gaagggtaag
    35101 gtttacttag taggggcagg accaggtgat tataaactca tgactttaaa aggtttagag
    35161 tgtataagaa aatcggatgt aatagtatat gatagattag caaatagtag ttatttaaga
    35221 gaagctaagc ctgattgtga acttatatat gtaggcaagg catcaagtaa tcatattttg
    35281 ccacaagaag atataaatag aattatagca gaaaaagcta aagaaggaaa aattgtaact
    35341 cgtcttaaag gaggagaccc ttatgtattt ggcagagggg gagaagaagc agagacttta
    35401 gtagatgaag atatagaatt tgaagtagtt ccaggtataa cttctgctat aggaggttta
    35461 tgttatgcgg gtattcctat aacacataga gaccatgctt cgtcatttca tgtaataaca
    35521 ggtcatttga agggtgatga tagtggagaa ttaaactgga atgctcttgc aaataacaaa
    35581 ggtactcttg tgtttttgat gggaatttca aacctagaga aaataagtga aaacttaatg
    35641 aaagaaggaa aagataagga tacacctgtt gctcttataa gttgggcaac tagatataat
    35701 caaagagttg ttacatctac acttgagaat gtttatgaaa ctgctattaa agaagaagta
    35761 aaaccgccaa ctcttatagt agttgggagt gttgtaggac ttagagaaaa gttgaacttc
    35821 tttgaaagta agcctttatt tggaaaaagt attgctgtaa ctaggtctag aaatcaaaat
    35881 agtgtattgg tagaaaaaat aatggattta ggtggaaatc ctatagaaat acctactatt
    35941 aaggtagaaa aaatacaaaa taatattaac ttagaaaatg aaataaaaaa tataaataag
    36001 tataattatt taatactaac tagtaaaaat gccgtagaaa tcttctttga aaagatatat
    36061 gaaatgaatt ttgatttaag gatattatct aatttaaagg tatgtgctat aggttctgct
    36121 acatcaaatg agttgaaaaa aagaggaatt atagcggata tagtaccaaa aaaatttgta
    36181 gcagagtcac tgtatgaaga gttagctcct attttaaatg ataacgataa tatacttata
    36241 cctagagcag aaaatgctag agattatctg gttgacaaac ttaaggctat ttgtgaagta
    36301 acagaagtac atatatatag aacagtaata gatgaggata aaaaaggtga gatattagat
    36361 attttaaatt ctaatgatat agattatata acatttacta gttcctcaac agtaaataat
    36421 cttgttgaaa ttataggaaa agaaaatatt aaaatattag aaaaaataaa aacactatct
    36481 ataggtccta taactacaga gacaataaat agtttgggaa taaaattgta caaagaatct
    36541 gctacatcta ctatagattc gttagtagat ttaattataa aaaattaatt ttggaggctt
    36601 gaatatgtta agaagaccaa gaagactaag agcaagtaaa gcaatcagaa atttggtaag
    36661 agaaactaag gtgaatgtag aagatttaat atatccactg tttgtagtag agggggaaaa
    36721 tataaaagaa gaaatcaatt ctttaccaga tgtatatcat ttatcaatag acatgctaga
    36781 agacgaaata aaagaaataa gtgagttggg aattgaacat ataatgttat ttggtgttcc
    36841 agatgaaaaa gatgagtgtg cttcacaagc ttttaatgat aatggaatag ttcaaaaggc
    36901 aattagaaag gtaaaagaaa taaattcaga tataaatgta ataacagatg tctgtatgtg
    36961 ccaatataca agtcatggac attgtgggat tttaactgat actggttatg ttgataatga
    37021 taaatcattg gagtatttgg ctaaaatatc tgtaagccat gctaaagcag gagctgatat
    37081 ggttgctcca tctgatatga tggatggaag aatacaagca ataagagaag ctttagatga
    37141 aaatggatta gaaaatgttg gaatcatggc ttatagtgtt aagtatgctt caaattatta
    37201 tggacctttt agagaggcag ctcattcagc accatctttt ggagatagaa aaacatatca
    37261 aatggaccca gcaaatagca atgaagctat aatagagact gaacttgata tattggaagg
    37321 tgcagatata cttatggtta aacctgcatt atcatattta gatattataa gaagagttaa
    37381 agataatttt gacttacctc tagcagctta taatgtaagt ggagaatact ctatgcttaa
    37441 gtttgctgtg aaggaaggtt tattaaatga agatgtaatt cttgaatcaa ttacatctat
    37501 aaaaagagca ggagcagata taataataac ttattttgct aaagacattg ctaaactgtt
    37561 gaaaaaataa attctagtag tataaagaat atcaaaaagt ataggaattg taattaacta
    37621 ttatacagta gttttgttta gacatttatt gaagaataat agaaactaat ttacaatttc
    37681 tatactttat ttatgtaact aaataaaatt tggaggtaga agatgctata tcctattaat
    37741 ttaaaattag atgagttaga tgtagttata attggtggtg gagaagttgc atataggaaa
    37801 tgtaaaaatt ttttagagtt taacaaaaat gttactatag tttctaaaca aattttaaat
    37861 aaattttatg atttaaaagg aaatataaaa ataataaaag atgattataa agaaatatat
    37921 ataaaagatg cttctgtaat aattgctgcc acaaataata gagagttaaa tatggaaata
    37981 ggattatatt gtagagcaaa aaataagcta gtgaatgtag ttgataatat agaaatatcg
    38041 aactttactg ttccatcata tataaaaaga ggagatttac ttataagtgt gtctactggg
    38101 ggcaagagtc cttcattatc atcaaagata aaaaaagaaa ttgaagagag atatactgaa
    38161 gattatgagg agtatttaaa tgtattagga gatataagaa aaaaggttat aaaaaaatac
    38221 gaagataaaa gtaaaagaaa agatgtgctt aatatgttgg taacacttga cctagaagaa
    38281 cttaagaagt ttgatatata aaaaataaaa taaaaaatgt taaaaaggtg ttgacggatt
    38341 atttttaaga tgatatagt
//
LOCUS       DAMJYN010000036        34795 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.037, whole genome shotgun sequence.
ACCESSION   DAMJYN010000036 DAMJYN010000000
VERSION     DAMJYN010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 34795)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34795)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34795
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.037"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(113..769)
                     /locus_tag="PC466_001919"
     CDS             complement(113..769)
                     /locus_tag="PC466_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDF2769303.1"
                     /translation="MELQDTIFKRQSVRKFKNQDVSDEDILKMIKAAGAAPSGKNIQN
                     WHFVVIKRRDLMEKIADVITKKQQEILVEMDKVSVDKANRFRKFVKNFTLFYLKAPVL
                     VLVFTKVYNPSGYYELELIDAPKETIDKLFIRNPGMQSLGASIENFTLSAIELGYGSC
                     WLTSQNYAADEIEAVLEAETGFEKGEYFLGAMLALGVPEDNLKSPSKKPVEEICTFIK
                     "
     gene            complement(824..1453)
                     /locus_tag="PC466_001920"
     CDS             complement(824..1453)
                     /locus_tag="PC466_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HDF2769304.1"
                     /translation="MVDSIIFDLDGTLWDSTEEVCKVWQDVLSKHKEIELSVTKDLFR
                     SLMGLSFEEIANRLFPNLSEEERMNLLNECSLKECDYLSENGAKLFDDIEDTLKLLSK
                     KYKLFIVSNCQAGYIESFLKAHKLEQYFIDFECPGNTGLHKGENNKLIIERNKLINPI
                     YVGDTQGDANSAKFVGIPFIYAKYGFGNVDVYDYFIDSFKDLLEHDILK"
     gene            complement(1584..2225)
                     /locus_tag="PC466_001921"
     CDS             complement(1584..2225)
                     /locus_tag="PC466_001921"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HDF2769305.1"
                     /translation="MKICIVLNGEIEDYEVTRDIIIKECYDCIICADGGANHTYKMEI
                     MPDYILGDLDSVEEEKINFYKNKGVKFEKFPSKKDETDTELCLFLAKTLKANHIDFFG
                     ALGGRIDHTLANIKLLYYLKEDGIYSRILSDKEEMYIVENEEISLYGNPGDTVSVTAI
                     KGDAKGVTLTGLEYPLDNYYMKYSVPIGISNVMLSNSCKIKVEQGCVLVVRNL"
     gene            complement(2234..2905)
                     /locus_tag="PC466_001922"
     CDS             complement(2234..2905)
                     /locus_tag="PC466_001922"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HDF2769306.1"
                     /translation="MIKLAPSILSADFAKLLEDVRKVESAGCEYLHIDVMDGHFVPNI
                     TLGPLVVKSLKKENINMVFDAHLMIENPDQYIEEFVKAGCDIITVHQEACVHLHRTIQ
                     NIKSHGIKAGVVLNPATPVDTIKHVLPDLDMVLLMSVNPGFGGQSFIPCVLDKIKELK
                     AIIDSQGLNIDIEVDGGISPKNVAEVVQAGANVIVAGSAIFGSDDIQETVNLFRKNAS
                     LEELV"
     gene            complement(2910..3794)
                     /gene="rsgA"
                     /locus_tag="PC466_001923"
     CDS             complement(2910..3794)
                     /gene="rsgA"
                     /locus_tag="PC466_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HDF2769307.1"
                     /translation="MLEGKIIKGISGFYYVDTYNGIYECKARGIFRKQKITPLVGDRV
                     KISIVDEDEKKGILEEIDSRDTELIRPPIANVDKALIVFAIKNPKPNLSLLDRFIVLA
                     EKENLETVIILTKADLDDNDTLETVKNIYELSGYKVIPVSNITKLNIDKVKEELKENV
                     VVFAGPSGVGKSSLLNEIDENFKLQTGVVSDKIKRGKHTTRHAELLKLEFGGMVADTP
                     GFSSLALEDIEEVELKDYFIEFDKFNDCKFGSKCIHENEPNCAIKEAVTNGEISKERY
                     DSYIQLLHEIRQNNSRRY"
     gene            complement(3892..4629)
                     /locus_tag="PC466_001924"
     CDS             complement(3892..4629)
                     /locus_tag="PC466_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDF2769308.1"
                     /translation="MKKKTVLITGGARGIGKAMSKAFAKEGYNVLVNFNKSENEAKEL
                     YTILNEKNFSVKLFKADISNREDVENMVDYCIKEFGGLDVLVNNAGVSQDKLFTDITD
                     EDWDNMMNINLKGSFYCSQVALKYMISEKKGNIINISSIWGISGASCEVHYSITKAGI
                     IGMTKALAKEVGPSNIRVNSIAPGVINTDMLSGYNEEDIDALVEETPLMRLGTPEDIA
                     NCAIFLASDKSNFITGQVISPNGGFVI"
     gene            complement(4737..6752)
                     /gene="pknB"
                     /locus_tag="PC466_001925"
     CDS             complement(4737..6752)
                     /gene="pknB"
                     /locus_tag="PC466_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HDF2769309.1"
                     /translation="MGDTILGNRYEIIRKIGDGGMAFVYEAKDRLLNRTVALKVLRPE
                     FVDDDEFLTKFKREAEAVASLSHPNIVNVYDVGEDGKVHYIVMEFVDGKNLKEIIQDE
                     GILDEYTALDITKQIAMALSAAHKKGIIHRDIKPHNILISNEGRVVKVADFGIAKAVS
                     NSTMTNIGSIIGSVHYFSPEQAKGKFVTNNADLYSLGIVLYEMLIGKVPFRGDSPISI
                     ALQHINDDIDFTSEEKVRIPQSVRTTIKKLTEKSSADRYQTAEELIEDIEYIEKNIDL
                     DFIKEYDDFATKKIDEKEINKVVNPTLAKPAPEKVVKPVEVADLDDDEDYYDDFYEED
                     EEEEEEEEEIMRAKKNQRPKSTPSKRTKKKKKKQESPKSRRRLKVIAAVLILILCAQV
                     FLAYKFLFAGGFGNKSLTVPNLVNMTLEEAQSAVEKEGLYLSVKSEEYNSEVDENCII
                     SQTPEGGSTNVKKGDTINVVVSKGSSQASVPNVVGLTLSNAKQLIEENNLKVGTVKYE
                     YSSIYKEGTVLSQSPGAGSSRAQEGDEVNLYVSKGSEKSNTQTPTVPDKKPTTPENNT
                     PTEPGSNSGNSGGNSGSSNSGNSGGNSGNNGGNSGGSNSGNSGGSSGGSNSGDNGGSS
                     GGSNSGDNGGSSGGSNSGDNGDSSGGSNSGDNGGTSSGTGANIGKTE"
     gene            complement(6769..7521)
                     /locus_tag="PC466_001926"
     CDS             complement(6769..7521)
                     /locus_tag="PC466_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HDF2769310.1"
                     /translation="MVYSCASHIGKIRKNNEDYCEGEVIDTEHGPIGIFAIADGMGGH
                     KKGEVASKLAVENIIDFLKENLLQHDNVKIDYIDDILKQAYNNVNSIVHKKSMEDIEF
                     EGMGTTLVTAIVYNNVLYVANVGDSRCYLLTDEKFDKITIDHSVVEELMMAHVITEEE
                     ARRHPQRNRITRAIGTDDMVVVDIFKKEIKKSDIILLATDGLTGFIDDEDIRDLILDY
                     EYERTSNISEELISMANDVSGKDNVSVIVIKV"
     gene            complement(7541..8572)
                     /gene="rlmN"
                     /locus_tag="PC466_001927"
     CDS             complement(7541..8572)
                     /gene="rlmN"
                     /locus_tag="PC466_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HDF2769311.1"
                     /translation="MEKKKIVLKNFTEDELKEFMKTIDEKPFRGSQIFSWIYKGAKTF
                     DDMNNIPKSLRNKLEEVSCIGNIDIELKLESKVDNTKKYLFLLDDGNIIETVMMDYDS
                     RVTVCVSNQVGCRMGCNFCASTMDGLIRNLEPWEILDQVIKIQEDTGKRVSNLVLMGS
                     GEPLDNFENTKQFLKIINEKNGLNIGYRHITLSTCGIVPKMYELADLEIAINLALSLH
                     SPYDEERRKIMPVANAYSIEEILNACRYYIKKTNRRVTFEYSLIKGVNDSEKEAKALA
                     KLLKGMLCHVNLIPINKVEEREYEKPDKAFIYKFRDSLEKNNIPATVRMSMGSDISGA
                     CGQLRRKYK"
     gene            complement(8580..9905)
                     /gene="rsmB"
                     /locus_tag="PC466_001928"
     CDS             complement(8580..9905)
                     /gene="rsmB"
                     /locus_tag="PC466_001928"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HDF2769312.1"
                     /translation="MDAREVGFKVLCDIEKNDNYSNIAINKHFKNLEISDMDRGLATE
                     LIYGVIENKYYLDYIINKLSKIKVKKMSTYVKIFLRMGTYQILFLDSISDYAAVNETV
                     KLSKKYDKKSSGFINAILRNEIRAKETIMDITEEDSVKYLSIKYSYNSWIIKNWIDKF
                     GQEFAEDLLEANNEKPSIYIRTNTLKISREELIEKLSEMGIVCLKVPMVEEAIKVEKM
                     KNIEKNELFKAGLFTIQDISSMIVGKVINPKEGSFVLDVCSAPGGKSTHLATLMNNTG
                     QVVARDIFEHKLKLINSTVNRLGLKNVFVERFDASEIDENSISKFDYVLADVPCSGFG
                     IIRRKPEIKYKKEEELKDITSIQKKILENASKYVKVGGTLVYSTCTIQDVENINIVTS
                     FVEENHNFEFVPIDTVNVDLDNQDKGYLKIYPNIHGIDGFFIAKLKRIR"
     gene            complement(9967..10668)
                     /locus_tag="PC466_001929"
     CDS             complement(9967..10668)
                     /locus_tag="PC466_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HDF2769313.1"
                     /translation="MYPVYGGFWGFDPTMVVLIPAILLTIYAQFKVSSTTNKYLRVNT
                     RRGYTGEQTARRVLDSNGLYDVKIEMVRGHLSDHYDPRRKAVRLSEDVYYGTSITSVA
                     VAAHECGHAIQHAKGYAPLQIRSSLVPVVNFASSISWFLIFLGFIMAGPFLKIGILLF
                     SASVLFQIITLPVEFNASSRAIVQLGNLGIIDESESRQSRRVLSAAALTYVAAALVSI
                     LQLLRLLLIAQRRND"
     gene            complement(10737..11489)
                     /locus_tag="PC466_001930"
     CDS             complement(10737..11489)
                     /locus_tag="PC466_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF116 domain-containing protein"
                     /protein_id="HDF2769314.1"
                     /translation="MTDIKKYLTSVGILILILGILIGVVNFFIISLTQIFSLMINIII
                     ISLILIILCSTAVTYRVIKGKYVNSNIMKINFNIVSGLFPIISFIASSFGMSKSDIRR
                     IYIKLNNEYIYSNKYNFNPEDIIILIPHCIQENSCKLKVTNDIDNCKECGRCNVGELI
                     KLKEKTNVKIFVATGGTLARKIIMDNKPKAVVAVACERDLTSGIQDIKKIPVLGVFNK
                     RPNGPCVNTNVDMMDIEKAIDFLTGKNILICN"
     gene            complement(11499..12428)
                     /locus_tag="PC466_001931"
     CDS             complement(11499..12428)
                     /locus_tag="PC466_001931"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HDF2769315.1"
                     /translation="MKIVFMGTPDIAVPCLQKIIDEKYEILGVVTQPDKPKGRGKKLG
                     MSPVKELAIENNIPVYQPVKARDKEFIDKIKSLNPDVIVVVAFGQILPKEILEIPKLG
                     CINVHVSLLPKYRGAAPINWVIINGEEKTGVTTMYMDEGLDTGDMILKTEVNLDENIT
                     AGELHDKMMNIGAETLKETLRLIEEGNAPREVQNHEEFSYAPIMNKSLGNIDFSKSAR
                     EIHNLVRGVNPWPSAYTIYNDVIMKVWKTKVLDEKSTKDVGTIIDVSKDGIKVSTIDN
                     VLLIEEIQMPNKKRMLVGEYIKGNTIETGLVLG"
     gene            complement(12443..12883)
                     /gene="def"
                     /locus_tag="PC466_001932"
     CDS             complement(12443..12883)
                     /gene="def"
                     /locus_tag="PC466_001932"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HDF2769316.1"
                     /translation="MALRQIVQIGEPVLRKKSKKVEKIDEKIIQLLDDMAETMYDADG
                     VGLAAPQVGILKRVVVIDIGEELIELINPEIIETSGEQIDEEGCLSVVGEAGNVRRPN
                     YVKVRALNRNGETIELEGEELLARAFCHEIDHLDGILFVDKIEK"
     gene            complement(12901..15426)
                     /gene="priA"
                     /locus_tag="PC466_001933"
     CDS             complement(12901..15426)
                     /gene="priA"
                     /locus_tag="PC466_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HDF2769317.1"
                     /translation="MNNILNLSRGFIMKKYAKVIVRSNTIYTDNLFTYQIPVFLSDVI
                     KIGHRILVPFGKGNKPTEAFVFQFTDSLDEKIKIKEIIDILDENPIFRKEDLELVYWM
                     KNRYLCTYIECINLIYPKGYKLNNYKVVLLGESLSGLNEIELKEKISTLSDKNREIVE
                     KVIDSKGKIKVDKLKYIPNLNSSLYTMNKNGIIKLCWEYKNHKNEKKVCYISLSLESD
                     KIDDYIEQNKINVGSKQKEILSFLKNNENVEINDLLDLLNASKQSINSLSKKKLITLE
                     FKDYYREPKSIYKSVLKSIKLNNEQQEAVDEIKSNMFVDDKKPYLIHGVTGSGKTEVY
                     MEIIEFALNQGLDSIFLVPEIALTPQTIDRLKSRFGDLVGVFHSKLSEGEKHDVYKAV
                     KAGKVRVLIGARSALFAPFNSLGLIIIDECHESSYKSEKNPKFNAIEVARFMALKNNI
                     TLILGSATPSIEEYYRAKSGEYKLINIKSRANDKPLPNIEVVDMKDELDKGNRSIFSL
                     KLQKEIRYAIEENNQVILFLNRRGYANFVSCRKCGYVFQCENCDISLTYHKKSNTGRC
                     HYCGYEKEIPKECPECKSTYVKPFGVGTQKIEEELKYIFPDIKTLRMDKDTTSKKGAL
                     DEILNKFKDKEADVLIGTQMLSKGLDFENVTLVGILSADMILNFPDFKSFETTFQLIT
                     QVSGRAGRADKEGKVVLQTYDTEHYAIKHAIEYDYEGFYEDEIKIRKAFGYSPFNNML
                     SVVVSGEDERLVIKNIKNMHASLIYLLEKRGINDLGFILGPNPCSISKINQNYRWQIL
                     FKDENIEINLLKGIIKYICITKRDLIFDKNINVSIDINPNSVL"
     gene            complement(15665..16864)
                     /gene="coaBC"
                     /locus_tag="PC466_001934"
     CDS             complement(15665..16864)
                     /gene="coaBC"
                     /locus_tag="PC466_001934"
                     /EC_number="4.1.1.36"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphopantothenoylcysteine
                     decarboxylase/phosphopantothenate--cysteine ligase CoaBC"
                     /protein_id="HDF2769318.1"
                     /translation="MLKDKTVVIGISGGIAAYKACDVVSKLKKLNANIHVIMTKSATE
                     FVKPLAFQSLSQNYVVEDMFEEPKTWEVEHISLAKKADLFLIVPASANVIGKIANGIA
                     DDMLTTTVMATKAQVLIAPAMNTNMYENPIVQKNIQTLKSFGYKFIEPESGRLACGDI
                     GTGKLANPDIIVEEVLTNLTKEQDLKGQSMIVTAGPTVESIDPVRYLTNRSSGKMGYS
                     IAREAIARGADVTLISGPTNLSIPQNLKKFVQIESAQDLYEAVVSNLSENKIVIQSAA
                     VADYKPKTYSDKKIKKKNDDLSIELSRNYDIAYEIGKIKEDKILIGFAAETNDLIEHA
                     KGKIKKKNLDFIVANDLTKEGAGFRADTNIVKIIDVEGNITEYPKMKKEEVANVILDK
                     VKALLEK"
     gene            complement(16869..17135)
                     /locus_tag="PC466_001935"
     CDS             complement(16869..17135)
                     /locus_tag="PC466_001935"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HDF2769319.1"
                     /translation="MLKPSINEVLEKIDNRYYLVGTVSKRARKLIDGEEPYVSNKTKE
                     KPVCVATKEVASGKITYRLLTEEEIEIEEARHHAEQHQQISEEE"
     gene            complement(17138..17755)
                     /gene="gmk"
                     /locus_tag="PC466_001936"
     CDS             complement(17138..17755)
                     /gene="gmk"
                     /locus_tag="PC466_001936"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HDF2769320.1"
                     /translation="MFVKKGLLLVVSGPSGAGKGTICKELLKENDTIKLSVSATTRKP
                     RTGEVDGVNYFFISKEKFEEMIEKGEFLEYAQIYDNFYGTPKAAIMECLEKGQDVLLE
                     IEMQGAKQIKEVCPEGVFIFVLPPSLEELKNRIVGRGTETEAEIEKRFSCAYEEIKMI
                     KDYDYFIFNEDVKTSAKEIEGIISSEKNKVSRYKNIIIEKFKEEL"
     gene            complement(17785..18666)
                     /locus_tag="PC466_001937"
     CDS             complement(17785..18666)
                     /locus_tag="PC466_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HDF2769321.1"
                     /translation="MAISMTGFGRGEYKDDNYYFLVECKTINHKYSDINIRLPRKISF
                     LEDKVRNLVKNYVKRGRVDLYIKFDLLGKEDVNLNFDEGLASQYIDILKEIKNKFDII
                     DDISVMNVAKFPDIVKIEEKEEDEDLLWSMLNQAVEDALIKLREMRSEEGKKLAEDIA
                     MRCDLLKNHIEEIEKYSSSVVEDYREKLNLRISELLDDPSIIDENRLAQEVAIYADKS
                     SITEEIVRFKSHIGQLKNTIFKDDSIGRKIDFLIQEMNRETNTIGSKSSDINITNLVV
                     EVKSELEKIREQIQNIE"
     gene            complement(18670..19500)
                     /locus_tag="PC466_001938"
     CDS             complement(18670..19500)
                     /locus_tag="PC466_001938"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HDF2769322.1"
                     /translation="MKFWKLHGIGNDFIAIDGRFDQINPSDYTALAKKVCHRRFSVGA
                     DGLLVVKDSKVADVEMVYYNSDGSRAAMCGNGLRCFCKFVYDNCIVKKESFTVDTLDG
                     IKDIKINLTNREINSIRVNMGKGSFIAKDVPVLTNKERFVQESIKVLDRELKVTSMLM
                     GVPHTVVIVDELDVDDVCKYGKEIENNKIFPEKTNVNFVKVEDKYNIHVYTWERGCGY
                     TLGCGTGMTASAIVCNLLNMVESSVNVTSQGGTVKIDVGDFSYMTGPAVKICEGVLEV
                     "
     gene            complement(19787..20821)
                     /gene="ltaE"
                     /locus_tag="PC466_001939"
     CDS             complement(19787..20821)
                     /gene="ltaE"
                     /locus_tag="PC466_001939"
                     /EC_number="4.1.2.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low-specificity L-threonine aldolase"
                     /protein_id="HDF2769323.1"
                     /translation="MRFIDLRSDTVTMPTDEMREAMAKAPVGDSIFRDDPTVNKLEEL
                     AAAKVGKEDAIFLPSGTFGNQLALFTHCLRGQEIIIGKGYHIVTHEVGAPAVIAGVQL
                     RTIDEDESGALNPELVEKAIRRDDIHEPQTGLICVENAYSGGTVVSLDNLREIKKIAE
                     KHNLPVHLDGARLFNAALTLGVEAKEIAKCCDSVMFCVSKGLAAPMGSILAGSKEFIA
                     KARRKQKVMGGGMRQVGIVAAAGIIAIEKMTLRLNEDHENAKYLACELNKIDGIEVNN
                     VNPDISMVFFKMSEDIIKEDVLIKEFFERNIKINKMENGEYRFVTHVDITKEDLDYVL
                     KTLKELIGVC"
     gene            21117..22892
                     /locus_tag="PC466_001940"
     CDS             21117..22892
                     /locus_tag="PC466_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NFACT family protein"
                     /protein_id="HDF2769324.1"
                     /translation="MALDGLVIHSIVDELSSKLTGGKIDKIHQPEDDEVIFNIRNNKE
                     NFRLVLSASASNPRVYLTSNYQKENPLKAPMFCMLLRKYIQGGNIVEISQIGFERIIK
                     ISVESLDELKEKTVKNIMIEIMGRHSNIIITHGEENKIIDSIKRVPFSISRVRQVLPG
                     HDYSLPPEQNKLNPLDDISKDLFIKNLEELEGPIFKSIYSKFLGISPIIAKEICYRAG
                     VNQNAIIKDISDEQFDSLHKVFCNLFNDINSNKYSPCIIIDKKVDKVVDFSCINLTLF
                     SDLSYINKDSMSRILEDFYRTKDIKDRINQRSSDLKKSISVKLDRLYNKLKKQEEELS
                     ESENADIYKIKGELITSYIYMVEKGMESIEIANFYDENCNDVTIELNKNLTPSENAQK
                     YFKKYNKMKHAKVEISHQISLNKEEIDYLENIVLSIENCENLAELQDIKEELAKVGYI
                     KTQKKNSKKDTIPSTKPHEFVSSDGFKILVGKNNKQNDYLTLRLADNDDLWMHTKNIP
                     GSHVIIKCAGKEVPDNTVFEGAMLAAFFSKSKLSSQVPVDYTKRKNVKKPSGSKPGMV
                     IYETNSTIYVTPEEETVAKLKVKSE"
     gene            complement(23107..24759)
                     /locus_tag="PC466_001941"
     CDS             complement(23107..24759)
                     /locus_tag="PC466_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HDF2769325.1"
                     /translation="MLLVKVENLKKYYADKLILDIDKLEILENDKIGLVGSNGQGKTT
                     LLKAILGEIEIDEGYTYLTESYSYISQSENNIETCSHSKEKSLLNAPDKFEEYLSGGE
                     KVKLKIADALSNKKNIIIADEPTSNLDKKSIGLLEDMFKRHEGALLLISHDRRFLDEL
                     CTTILELEDGKLKAYKGNYTDYLMQKDEEVKRADFEYQEYVKEKKRLEKALLYKKALS
                     DGIRKTPKRMGNSEARLHKMGGQTNKKKLDSNVKAIKSRIDKLEVKNKPKVSKEMNIK
                     IQDGMEIISKNLLEVKDMTLKLENKLLLDNVSFKIKRGKKIALLGDNGCGKSTLIKEI
                     LADKNDNIKINNKVKVGCFDQNQSLLDEEKSVLYNTKVNSSFDESFIRINLSLFGFKG
                     DDVYKKVKVLSGGEKVKIALCKIILEDNNFLVFDEPTNYLDIKSMEALEKALINTDKT
                     MLIVSHDRVFVSHICNYIIEIKDAKIREFDCNYDEYIISRNKKTPSRDKQIKKENLLV
                     LENRLTTVISMLSIEKDNLKKELYESEYNELLKQITKLKNSF"
     gene            complement(25058..26269)
                     /locus_tag="PC466_001942"
     CDS             complement(25058..26269)
                     /locus_tag="PC466_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HDF2769326.1"
                     /translation="MKKTIMSLQHLLAMFGATVLVPILTGFNPSVAIFCAGVGTLIFH
                     FCTEGKVPAFLGSSFAFIPVILAAKEAYGGDLAYAQGGIIVAGLIYIIMSIIVKIVGV
                     NKIKLYFPAQVTGAMIVVIGLNLLPTAFSMASANFVIAFITLAIAILTNKFGRGFIKQ
                     LGILIAVFSGYIICLLLRLVDITTITEASLFAIPNFTVPKFSLGAIVIISPVVLAVFM
                     EHIGDMTTNGAVVGKNFIENPGLNRTLLGDGFATIVAGCLGGPANTTYGENTAVLAIT
                     KNYDPSILRRTAIFAILLACVGKFGGFLQSIPGSVMGGISIMLFSMITYVGLKTIRDS
                     SCVESKINILIIAVILLIGLGTTYLSNKGISIGIPITSTVKITGLSLAAIVGIVLNRI
                     LNNQDFKVEEE"
     gene            complement(26553..27086)
                     /gene="pyrR"
                     /locus_tag="PC466_001943"
     CDS             complement(26553..27086)
                     /gene="pyrR"
                     /locus_tag="PC466_001943"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001156491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HDF2769327.1"
                     /translation="MVEKAQLMDEKAIARAITRISHEIIERNKGVENLVLVGIKTRGV
                     PIANRISKKIEQIEGTKVDTGDIDITLYRDDLEKIHVEPVVKGTYLDFNVNDKTVVLV
                     DDVLYTGRTVRASLDAIIDIGRPKSIQLAVLVDRGHRELPIRADYVGKNVPTSRHEII
                     SVSLLEIDGEDSVTIKE"
     gene            complement(27445..28392)
                     /locus_tag="PC466_001944"
     CDS             complement(27445..28392)
                     /locus_tag="PC466_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HDF2769328.1"
                     /translation="MFYFLKVKVGDIMDEVKEFLVLEEEEEVRLDIYLAEQLGDMSRS
                     YIQKIIKDGKVKVNNKVEKAKYLVKEEDNIVIEIPEPKVLEVLPQDIPIDIVYEDDDV
                     LIINKPQDMVVHPAPGNYENTLVNGILYHCKDKLSSINGVIRPGIVHRIDKDTSGLLM
                     IAKNNYAHNFLAEQLKEHTITREYEFICYGVVKEDKITVDKPIGRNPKDRLKMAVVKD
                     GKNAITHFEVVERFDKFTHMRARLETGRTHQIRVHALSINHPLLGDFVYGPKETKFKL
                     KGQTLHAKKLGFIHPTTKEYIEFNSELPEYFKEAIKKIK"
     gene            complement(28361..28807)
                     /gene="lspA"
                     /locus_tag="PC466_001945"
     CDS             complement(28361..28807)
                     /gene="lspA"
                     /locus_tag="PC466_001945"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HDF2769329.1"
                     /translation="MLYILIIILLIGLDQLSKIWVLNNLVDVSTIPIINNVFHLTYVE
                     NRGAAFGLLQNNQWIFIIVALLATVFGLYYLNTRKVHIFGRLGIILIISGALGNLIDR
                     VRLGFVVDYFDFRVIWEYVFNVADVFVVVGTVFLCIYVLFFESKSR"
     gene            complement(29117..29896)
                     /locus_tag="PC466_001946"
     CDS             complement(29117..29896)
                     /locus_tag="PC466_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HDF2769330.1"
                     /translation="MKKAIWGICICLLSIVGVYTYNHNTHNQNSSKETYTLNDNIKDD
                     YEDVIIKKGNEDEKILALTFDDGPDEDFTPQILDILKKNNVKATFFVVGEKVEYNKEL
                     LKRQYDEGHEIGNHTFTHINVAKNSYGSVEKEITDTQNIIKSVIGVEPKIFRPPYRAM
                     SKSVCDIIVSKGMNIILWSNLDPRDWSNPGVDTIINTILTKVQNGNIILLHDYNTKRN
                     DKSQTIQALEVVIPKLKERGYKFVTVSELIQHLDKNKQVQK"
     gene            complement(29946..30428)
                     /locus_tag="PC466_001947"
     CDS             complement(29946..30428)
                     /locus_tag="PC466_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraR/DksA C4-type zinc finger protein"
                     /protein_id="HDF2769331.1"
                     /translation="MDTKKYKDKLLKEREKLTNLVVDMKDNTLFGDTTKHTSEKYSSG
                     ELSSYDNHIGDMGTDLYMQNMQNSLINHEEGRLYQIDSALSKIENGTYGFCDLCHNQI
                     DLERLDILPDTNLCNNCAKKENALLGDAMQNPDVEDSNFYSEDLTNLTDLNKNGTLRD
                     "
     gene            complement(30612..32033)
                     /locus_tag="PC466_001948"
     CDS             complement(30612..32033)
                     /locus_tag="PC466_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon starvation protein A"
                     /protein_id="HDF2769332.1"
                     /translation="MVSFLGSIVVLIVGYFIYGTFVEKVFGINDKNQTPAIACRDGVD
                     YVPMKWKRIFLIQFLNIAGLGPIFGAIQGALFGPSAFLWIVFGTIFAGGVHDFASGYL
                     SMKNKGTSASELVGLYLGNGAKIAMRIFSVILLVLVGVVFVTGPAGLLKTLTGVNAQI
                     WVGVIILYYIMATVLPIDKLIGKIYPLFGAALLIMAVGVAGGLIIKGYNIPNINLQNM
                     NPNGTPLFPYLFITIACGAISGFHATQSPLMARCVEKESEARPVFYGSMVAEGIIALV
                     WAAAAMSYFHGIPQLNVIFNDGGAATVVNTVSVGLMGPIGGALAILGVVACPITSGDT
                     AFRSARLTIADAMNYNQDAVKNRFLIALPLFAVGVALTFIDFNIIWRYFSWANQTLAM
                     IMLWTGSAYLVKANKNHYITTLPALFMTVVTFSYIMQAKEGFRLPVNISNGIGIVVAI
                     ILGLLFFKKAKDIKEQNAHKLAS"
     gene            complement(32179..32949)
                     /locus_tag="PC466_001949"
     CDS             complement(32179..32949)
                     /locus_tag="PC466_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001295458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2769333.1"
                     /translation="MRAIIVEDEFPARKELRYFIENKSSIEVVNEFTNGIEVLDFIQE
                     NKIDVIFLDINIPHLDGMLLAKTLNQFKSRPKIVFITAYENYAVDAFSLDVFDYVLKP
                     YSEERIISMLNKLEKSEMSDIELSNSNSNLYKYKKETVNQEIEEITHKISLWKGDKLV
                     VIDIDDIYYCEANERQTFIYTEKEKFILKEGISEVENLINDKTFFRTHRSYIVNLTKV
                     KEIIPWFNNTYILKLKNSDYEVTVSRSKVKEFRLLMHI"
     gene            complement(32954..34156)
                     /locus_tag="PC466_001950"
     CDS             complement(32954..34156)
                     /locus_tag="PC466_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HDF2769334.1"
                     /translation="MKTSILIALIEKTSLIVVLFLLITKLKIFKQIFQKEEYSFNDLV
                     CIALVFTFLAIFGTYSGINYMGSIVNTRIISIVSGGILFGPMVGITAGVFSGIHRYFM
                     DIGGITSVPCLLSSILAGVLSGFLYKRIPKQHRVMYGILVGMISESFTILLIYLISYP
                     HSLAIQIIVGIYLPLIVGQIGIGFVISIVEGIEKDKKDIEARNKAEIKALQRQINPHF
                     LFNSLNTIASFIRFSPDKARELIINLSTYLRYNLEYSDNLIDINKEIEQVKSFVEIEK
                     ARFGELLTVSYDIEDVNIKIPSLIIQPLVENAIIHGILESGRAGVVKISIKKLPYSLE
                     NTVRISIEDNGIGISEEIINNVYQDNMPENKIGLYNVHLRLKLMYGRGLNIRRTDNGT
                     LIVFYVKE"
BASE COUNT        11090 a         6390 c         3505 g        13810 t
ORIGIN      
        1 tgatttgaaa tataaaatta atatcaataa aacctacttt ttaatttttt aaatatttat
       61 ttttaattta tcttgttttt aatttacttt gattttaaaa tgtccttgac ttttatttta
      121 taaatgtaca tatttcttct actggttttt tagatggact cttcaaattg tcctctggca
      181 ctccaagagc taacattgca cctaaaaaat actctccctt ttcaaaacca gtttctgctt
      241 ctaaaacagc ttctatctca tctgctgcat agttttgact tgtcaaccaa caagaaccat
      301 atccaagttc aattgctgat agtgtaaagt tttcaattga agcacctaga ctctgcatac
      361 ctggatttct tataaataat ttatctatag tctccttagg tgcatctata agctctaatt
      421 cataatatcc tgatggatta tatacctttg taaaaactaa tactaaaact ggagctttta
      481 agtaaaatag tgtaaagttt ttaacaaatt ttctaaatct attagcctta tccactgata
      541 ctttatccat ttccacaagt atttcttgtt gctttttagt tatcacatct gctatctttt
      601 ccattaaatc acggcgtttt ataacaacaa aatgccagtt ttgaatattc ttgcctgatg
      661 gtgctgcacc tgctgctttt atcattttta aaatatcttc atctgataca tcttgatttt
      721 taaactttct tacactttgt cttttaaaaa tagtatcttg taattccatt tttaaatccc
      781 cccataactt ttttattatt ttaatataat ttttaaactc atcttatttt aatatatcat
      841 gttctaacaa atctttaaat gaatctataa aataatcata tacatctaca ttcccaaacc
      901 catatttggc atatataaaa ggtataccta caaacttagc actatttgca tcaccttgcg
      961 tatcaccaac atagattgga tttattaatt tatttctttc aattataagt ttattatttt
     1021 ctcctttatg caaaccagta ttaccaggac attcaaaatc tataaaatac tgttctagtt
     1081 tatgtgcttt taaaaaagat tctatatatc cagcttgaca attacttact ataaataatt
     1141 tatatttttt agatagtaat ttaagagtat cttctatatc atcaaataat ttagctccat
     1201 tttcagataa atagtcacat tctttcaaag aacattcatt caataaattc attctttctt
     1261 cttcacttaa atttggaaat aaacgatttg ctatttcctc aaaagaaagc cccataagac
     1321 ttctaaataa atcttttgtg acacttaatt ctatttcctt atgtttactt aaaacatcct
     1381 gccagacttt gcatacttct tcagttgaat cccacaatgt tccatctaaa tcaaaaataa
     1441 tactatctac cacaaaaaat cccccttatg tcaaagttta ttatatattt ataattatat
     1501 actaaaaagc agatacaatc ataaatatat tttacttgat tgtatctgct ctacaatata
     1561 aaaccaattg tcaaaatcaa attttataaa tttctaacta caagtacaca gccttgctct
     1621 actttaatct tacaagaatt actcaacata acatttgata ttccaatagg tacagagtat
     1681 ttcatataat aattatcgag agggtattct aagccagtaa gtgttacacc cttagcatca
     1741 ccttttatag ctgttacaga aacagtgtcc cctgggtttc catacaatga aatttcctca
     1801 ttttcaacta tatacatctc ttctttatca gaaagtatcc tagaatatat accatcttct
     1861 tttaaataat ataatagctt tatatttgca agagtgtggt caatccttcc ccctaaagca
     1921 ccaaaaaaat caatatgatt tgctttaagt gtcttagcta aaaaaagaca aagctctgta
     1981 tcagtctcat cttttttaga tggaaatttt tcaaatttaa cacctttatt tttatagaag
     2041 tttatctttt cttcttctac tgaatctaaa tctcctaata tataatctgg cattatttcc
     2101 attttataag tgtgatttgc ccctccatct gcacatatta tgcagtcata acattcctta
     2161 attataatat ctcttgtaac ttcgtaatct tcaatttcgc catttaaaac aatacagatt
     2221 ttcattatta aatttaaact aattcttcaa gagaagcatt ctttctaaat aaattaactg
     2281 tttcttgaat gtcatcactt ccaaatattg cagaacctgc tactattaca ttagctcctg
     2341 cttgtacaac ttcggctacg tttttagggc ttataccacc atcaacttct atatcaatgt
     2401 ttaatccttg actatctata atagctttta actctttaat cttatctaaa acacaaggaa
     2461 taaatgattg tcctccaaat ccagggttaa cagacattaa taataccata tctaaatcag
     2521 gtagtacatg tttaatcgta tctactggtg tagctggatt aagtactaca ccagctttta
     2581 ttccatgtga ttttatattt tgtatagttc tatgtagatg aacacaagcc tcctggtgaa
     2641 cagttattat atcacatcct gcttttacaa attcttcaat atactggtct ggattttcta
     2701 tcataagatg agcatcaaat accatattta tattttcttt ctttaaactt ttgactacaa
     2761 gtggtcctaa tgtaatgttt ggtacaaagt gtccatccat tacatcgata tgaagatatt
     2821 cacatcctgc actttctact tttcttacat cttctaataa ttttgcaaaa tctgctgata
     2881 atattgatgg tgctaattta atcatttttc taatacctcc tactattatt ttgtcttatt
     2941 tcatgtagca gctgtatata actatcatat ctttctttag atatttctcc atttgtaaca
     3001 gcttctttta tagcacaatt aggttcattt tcatgaatac actttgaacc aaacttacaa
     3061 tcattaaatt tatcaaattc tataaaataa tctttaagtt caacttcctc tatatcttca
     3121 agtgcaaggg aactaaaacc tggtgtatct gcaaccattc caccaaattc caattttaaa
     3181 agttcagcgt gacgagtagt atgttttccc ctttttattt tatcacttac cactcctgtt
     3241 tgaagtttaa aattttcatc tatttcattt aataagcttg attttccaac tccagatggt
     3301 cctgcaaaca ctactacatt ttcttttaat tcttctttta ctttatctat atttaactta
     3361 gtaatattgc ttacaggaat gactttatag ccactaagtt catatatatt tttaacagtt
     3421 tctaatgtat cattatcatc taaatctgct tttgtaagga ttattacagt ttctaaattt
     3481 tctttttctg ccaaaactat aaatctatct aaaagagata agtttggttt aggatttttt
     3541 attgcgaata ctattaatgc tttatctaca tttgcaatag gaggtcttat aagttctgta
     3601 tctctactgt cgatttcttc taagataccc tttttttcat cttcatcaac aatgcttatt
     3661 ttgactctat caccaaccaa aggtgttatt ttctgctttc taaatatccc tctagcctta
     3721 cattcataaa taccattata agtatctaca taataaaatc cactaatccc ctttataatt
     3781 tttccttcta gcatcaaatg cctcccttta taaaatttat ataaacacat actgtttatg
     3841 aatagtatat cgtgttattc tttcctattt ttatataata ccacattttt tttaaataac
     3901 aaatcctccg tttggactaa ttacctgacc agtgataaaa tttgatttgt ctgatgccaa
     3961 gaaaatagca caatttgcta tatcttctgg agttcctagc ctcattagag gggtttcttc
     4021 cacaagagcg tctatatctt cctcattata tccagataac atgtcagtat taatgacacc
     4081 tggagctatg ctatttactc taatatttga tggtcctact tctttagcta atgcctttgt
     4141 catacctatt atacctgctt ttgttataga ataatgcact tcacaagacg cacctgatat
     4201 accccagatt gaagatatat taattatatt tccttttttt tctgatatca tgtattttaa
     4261 agcaacttgc gaacaataaa agcttccttt taaattaata ttcatcatat tatcccaatc
     4321 ttcatcggtt atatctgtaa acaacttatc ttgacttaca ccagcattgt ttacaagtac
     4381 atccaatcct ccaaattctt ttatacaata atctaccata ttctctacat cttctctatt
     4441 tgaaatatca gccttaaaaa gttttacaga aaaatttttt tcatttaata tagtatacaa
     4501 ctctttagct tcattttctg acttattaaa atttactaat acattgtaac cttcttttgc
     4561 aaaagcttta gacatagctt taccaatccc tctagctcct cctgtaatta aaacggtttt
     4621 cttcttcata aatacttttc tccttatatt ataaccaatt cagtatttta tacaaaacaa
     4681 actgcccttt aaagaaaata ttttctataa aaggacagct cttattttat taatatttat
     4741 tctgttttac caatgtttgc gccagttcct gatgaagttc ctccattatc tcctgagttt
     4801 gagcctcctg aactatctcc attgtctcct gagtttgaac ctcctgaact tcctccatta
     4861 tctcctgagt ttgaacctcc tgaacttcct ccattatctc ctgagtttga gcctcctgag
     4921 cttcctccac tatttcctga gtttgaacct cctgagttac ctccattatt gcctgagttt
     4981 cctccactat ttcctgagtt tgaacttcct gaatttccac cactgttccc tgagtttgaa
     5041 ccaggttctg ttggtgtatt attctctggt gttgttggtt ttttatctgg tactgttgga
     5101 gtctgtgtat ttgatttttc tgaacctttg cttacatata ggtttacctc atcaccttcc
     5161 tgagctcttg atgagccagc acctggactc tgacttaaaa ctgtaccttc tttatatatt
     5221 gagctatatt catacttaac agttcccact tttaagttat tttcttcaat aagttgtttt
     5281 gcattactca aagtaagtcc caccacatta ggaacagatg cctgacttga acctttactt
     5341 acgacaacat ttatagtatc accctttttg acatttgtac ttccaccttc aggtgtctgt
     5401 gatattatac aattttcatc aacttcacta ttatactctt cactttttac actcaggtat
     5461 aatccttctt tttcaacagc actttgagct tcttctaatg tcatatttac aagattagga
     5521 acagtcaaag atttattgcc aaaccctcca gcaaataaaa acttatatgc taagaatact
     5581 tgagcacaca atatcagtat caaaacagcc gcaattactt ttaatcttct tctagatttt
     5641 gggctttcct gttttttctt ctttttctta gttctcttac ttggagtact cttaggtctc
     5701 tgattctttt tagctctcat tatctcttcc tcttcttctt cttcttcttc atcttcttca
     5761 taaaaatcat catagtaatc ttcatcatca tccaaatcag ctacttcaac aggcttaacc
     5821 actttttcag gagctggttt tgcaagtgtt ggatttacaa ctttattaat ttctttttca
     5881 tcaattttct tagttgcaaa atcatcatat tcttttataa aatctaaatc aatatttttt
     5941 tctatatact ctatatcttc tatcaattct tcagcagttt gatatctatc tgcgctagat
     6001 ttttctgtaa gcttttttat tgtagttctt acactttgag gaatcctaac tttttcttct
     6061 gatgtaaagt ctatatcatc attaatgtgt tgaagtgcta tagaaattgg actatctccc
     6121 ctaaatggaa cttttcctat caacatttca tataaaacta tacctagaga atacaggtca
     6181 gcattattag ttacaaattt acctttagct tgctctggtg aaaaataatg cactgaacct
     6241 attatactac caatattagt cattgttgaa tttgaaacag ctttggctat accaaaatca
     6301 gccactttta ctactcttcc ttcatttgat atgagaatat tatgaggttt tatatctcta
     6361 tgtataatcc cctttttgtg cgctgcacta agtgccatag ctatttgttt tgttatatct
     6421 aatgcagtat attcatctaa tataccttca tcttgtataa tctcttttag attcttccca
     6481 tctacaaact ccattacaat gtagtgaact tttccatctt caccaacatc ataaacattt
     6541 actatatttg gatgtgaaag acttgctact gcttctgcct ctcttttaaa ctttgttaga
     6601 aattcatcat catctacaaa ttcaggtcta agtactttaa gtgcaacagt cctgtttaat
     6661 aatctgtctt tagcctcata tacaaaggcc attcctccat caccaatctt cctgatgatt
     6721 tcatatcgat ttcctaaaat tgtatctccc acaatatcac cgtcctaatt atacttttat
     6781 cactataacc gaaacattat ctttaccaga aacatcattg gccatactta tcaattcttc
     6841 acttatatta ctagttctct catattcata atctaatatt aaatctctta tatcttcatc
     6901 atcaataaac ccagttaatc catctgtcgc aagaagtatt atatcacttt ttttgatttc
     6961 tttcttaaaa atatctacaa caaccatatc atctgttcca attgctctag ttattctatt
     7021 tctctgtgga tgtcttcttg cctcttcttc tgtaatgaca tgggccatca taagttcttc
     7081 aaccacggaa tggtctatag ttattttatc aaatttttca tctgttaaca aataacatct
     7141 gctatctcca acatttgcca catataagac attattatac actatagccg taactaatgt
     7201 agttcccatt ccttcaaatt ctatatcttc catagatttt ttgtgcacaa ttgagtttac
     7261 attattataa gcctgtttta atatatcatc tatatagtct atttttacat tatcatgttg
     7321 taataagttt tcctttagaa aatcaattat attttctact gctaatttac tggcgacttc
     7381 acctttttta tgtccaccca ttccatcagc tatggcaaat attcctattg gaccatgttc
     7441 tgtatctata acttctccct cacaatagtc ttcattgttt tttcttattt ttcctatatg
     7501 ggaggcacaa ctataaacca tacgacttcc tccttacaaa ttacttgtat tttcttctca
     7561 attgaccaca agctccacta atatcagaac ccatagacat cctaactgtg gcaggtatat
     7621 tgttcttctc caaactatcc ctaaatttat aaataaatgc tttatctggc ttttcgtatt
     7681 ctctttcttc aactttattt attggaatta aatttacatg acatagcata ccttttagga
     7741 gcttagctaa tgcctttgct tctttttctg agtcatttac tccttttata agagaatatt
     7801 caaatgtaac ccttctattt gtctttttta tataatatct acatgcattc aatatttctt
     7861 caatagaata agcatttgct acaggcataa tttttcttcg ttcttcatca tatggtgaat
     7921 gaagtgataa agctaaattt atagctattt ctaagtctgc caactcatac attttaggta
     7981 ctattccaca agttgaaaga gttatatgtc tataccctat attaagacca tttttttcgt
     8041 taattatttt taagaattgt tttgtatttt caaagttatc aagtggctca ccactcccca
     8101 tcaatacaag atttgatacc ctcttaccag tatcttcttg aattttaata acttggtcta
     8161 aaatttccca tggctctaag tttctaatta atccatccat tgtagatgca caaaaattac
     8221 atcccatcct acaacctact tggttagaaa cacagacagt aactctacta tcataatcca
     8281 tcatcacagt ttctattata tttccatcat ctaataaaaa caaatatttt tttgtattat
     8341 ctaccttaga ttctaacttt aattctatat ctatattccc tatacatgaa acctcttcta
     8401 atttatttct caaacttttt ggtatattgt tcatatcatc aaaagttttt gcacccttat
     8461 atatccaaga gaatatttga cttcctctaa agggcttttc atctatagtt ttcataaatt
     8521 ctttaagttc atcttcagta aaatttttta atactatctt tttcttttcc attctctcac
     8581 taccttattc tctttaattt tgctatgaaa aaaccatcta taccatgaat attaggatat
     8641 atctttaaat atcctttatc ttgattgtct aagtctacat ttactgtatc aattggaaca
     8701 aattcaaagt tgtgattttc ttcaacaaaa gaagtaacta tatttatatt ctccacatct
     8761 tgaattgtac atgtactata tactaaagtt ccaccaactt tgacatattt agatgcattt
     8821 tctaaaattt tcttttgtat agaagtgatg tcttttaact cttcttcttt cttatactta
     8881 atttctggtt tacgtcttat tataccaaaa ccagagcaag gaacatctgc taaaacataa
     8941 tcaaatttac ttatactatt ttcatcaatc tcagaagcat caaatctttc tacaaacaca
     9001 tttttaagcc ccaatctatt tacagtagag tttataagct ttagtttatg ctcaaaaata
     9061 tctctagcta ctacttgacc cgtattgttc attaaagtag ctaagtgagt agatttccct
     9121 ccaggagcac tacatacatc caaaacaaat gaaccttctt ttggattaat tactttccct
     9181 actatcatag aacttatatc ttgaattgta aataaaccag ccttaaataa ttcatttttt
     9241 tctatatttt tcattttttc gactttaata gcttcttcta ccataggaac ttttaaacat
     9301 acaataccca tttcacttaa tttttcaata agttcttctc tacttatttt aagtgtattc
     9361 gttcttatat agatactagg cttttcatta tttgcttcca acaaatcttc agcaaattct
     9421 tgtccaaatt tatctatcca gttttttata atccaagagt tataggaata ctttatagat
     9481 aagtatttta cactatcttc ctcagttatg tccattatag tctctttagc tcttatttca
     9541 tttctaagaa tagcatttat gaaaccagaa gattttttat catatttctt agataatttt
     9601 acagtttcat taactgctgc ataatctgat atactatcta aaaataaaat ctgatatgtt
     9661 cccattctta aaaagatttt aacataagtt gacatttttt ttacctttat ttttgaaagt
     9721 ttattgatta tataatctaa ataatattta ttttctatta ctccataaat taactctgtt
     9781 gcaagtcctc tatccatatc acttatttct aaatttttaa aatgcttatt tattgcaata
     9841 tttgaataat tgtcattttt ttctatatca cataatactt taaatccaac ttctcttgca
     9901 tccatataaa tttctccctt ttattaaaca taaaaaaggg ttgtttctaa acaacccact
     9961 ttacttttag tcatttcttc tttgagctat tagtaacaat ctaagtaatt gaagtattga
    10021 aaccaatgct gctgcaacat atgttaaagc tgctgctgaa agtactcttc tactttgtct
    10081 tgactcactt tcatctataa tacctaaatt cccaagttga acgattgctc tacttgaagc
    10141 attaaattct acaggcaatg ttattatttg gaataacact gaagccgaaa acaatagtat
    10201 accaattttt aaaaatggac cagccataat aaatcctaaa aatattaaaa accaagatat
    10261 acttgaagca aaattcacta ctggtactaa actacttctt atttgaagag gcgcataacc
    10321 tttagcatgt tgtatggcat gaccacactc atgtgcagct actgcaacag aagttataga
    10381 tgttccataa tatacatctt ctgacaacct tacagccttt cttcttgggt cataatggtc
    10441 acttagatgc cctctaacca tttctatctt tacatcatac aaaccatttg aatcaagtac
    10501 tcttcttgct gtttgctctc cagtatatcc tcgacgtgta tttactctta aatacttatt
    10561 tgttgttgaa ctcactttaa attgtgcata tatagtaagt aatatagctg gaattaatac
    10621 aaccattgtt gggtcaaatc cccaaaaacc gccatataca gggtacataa ataacactct
    10681 cctaaaatat atttttatta tacatcctct taatattcac ttaacttaaa aacagtttaa
    10741 ttacaaatta atatattttt tcctgttaaa aagtctatag ctttttcaat atccatcatg
    10801 tctacattag tatttacaca aggtccatta ggtcttttgt taaatacacc taaaacagga
    10861 attttcttaa tatcttgtat tccagatgtc aaatctcttt cacatgcaac agctacaaca
    10921 gctttaggtt tattatccat tataattttt ctagctaggg ttcctcctgt agctacaaat
    10981 atttttacat tagttttttc ctttagctta attaattctc ctacgttgca tcttccacat
    11041 tctttacaat tatctatatc attagtaact tttaatttac aactattctc ttgaatacaa
    11101 tgaggtatta aaattattat atcctctgga ttaaaattat atttattact gtatatatat
    11161 tcattattta actttatata tattcttcta atatcacttt ttgacatacc aaatgatgat
    11221 gcaatgaaag atataatagg aaataatcca ctgacaatat taaaatttat tttcattata
    11281 tttgagttaa catactttcc tttaattact ctataagtaa ctgctgttga acatagtatt
    11341 ataagtatta gtgatattat tataatattt atcatcaagg agaatatttg agttaaactt
    11401 attataaaaa aattaacaac tcctatcaaa attcctaata ttaaaatcaa aatcccaaca
    11461 cttgttaaat acttctttat atctgtcata cttttcacct aacccaatac taaaccagtt
    11521 tctatagtat tcccttttat atattcacca accaacattc tctttttatt cggcatctga
    11581 atttcttcaa ttaaaagtac attatctata gtacttactt ttatcccatc tttgcttaca
    11641 tcaattattg tacctacatc ttttgtgctt ttttcatcta acactttagt tttccaaact
    11701 ttcattatga catcattata gatagtataa gcacttggcc atggatttac tcctctaact
    11761 aaattgtgta tttctctggc actttttgaa aaatctatgt tacctaatga tttattcatt
    11821 attggcgcat aggaaaattc ttcatgattt tgtacttctc ttggagcatt tccttcttca
    11881 attaatctta atgtttcttt taaagtttct gctcctatat tcatcatttt atcatgaagt
    11941 tctcctgctg ttatattttc atcaagattt acttctgtct ttagtatcat atctccagta
    12001 tctaaccctt catccatata catagttgta acaccagtct tttcttcacc atttattatt
    12061 acccaattta taggtgccgc acctctatat tttggaagta aagaaacatg aacatttata
    12121 catccaagtt taggaatctc taatatttct tttggaagta tctgtccaaa agctacaact
    12181 actattacat ctggatttaa agatttaatt ttatctataa attctttatc tctagccttt
    12241 actggttgat atacaggtat attattttca attgccagtt cttttactgg actcatacct
    12301 agttttttac ctcttccttt tggtttatct ggttgagtta caacacccaa tatttcatac
    12361 ttctcatcta ttattttttg taaacatgga actgctatat caggagttcc cataaatact
    12421 attttcatca aatcaactcc tactactttt ctattttgtc aacaaataaa attccatcta
    12481 agtggtctat ctcatgacaa aatgctctag ctaaaagttc ttctccctct aactctattg
    12541 tttcgccatt tctatttaaa gctctgacct ttacataatt tggtcttcta acatttccag
    12601 cttctccaac aacacttaaa catccttcct catctatttg ctccccagat gtttctatta
    12661 tttcaggatt tataagttct ataagctctt ctccaatatc tattactact actcttttta
    12721 atattccaac ttgaggtgca gccagtccaa caccatctgc atcatacata gtttctgcca
    12781 tatcatctaa taattgtatt atcttttcat caattttttc aacctttttt gatttttttc
    12841 ttaatactgg ttctcctatt tgaactattt gtcttaaagc cattataatt cctcctaaat
    12901 ttataataca ctgtttggat taatatctat agatacattg atattcttat caaatatcaa
    12961 atctcgtttt gttatacata tatattttat tatacccttt aagagattaa tttcaatatt
    13021 ttcatcttta aagagtattt gccatctata attttgattt atttttgata ttgaacatgg
    13081 atttggacct aatataaatc ctaaatcatt tatacccctt ttttctaata aataaatcaa
    13141 tgatgcatgc atatttttta tattttttat cactaatctt tcatcttcac cactaacaac
    13201 tacacttaac atattattaa aaggagaata tccaaatgct tttcttattt ttatctcatc
    13261 ttcataaaaa ccctcataat catattcaat agcatgctta atagcatagt gttcagtgtc
    13321 ataagtctga agtactactt ttccctcttt atcagctctc cctgctcttc cagagacttg
    13381 agttatcaat tgaaatgtag tttcaaaact tttaaagtct ggaaaattta atatcatgtc
    13441 tgcagacaaa atacctacta aagttacatt ctcaaaatcc agccctttac ttaacatctg
    13501 tgttccaata agtacatctg cttctttatc tttaaattta tttagtatct catctaaagc
    13561 accttttttt gaagttgtat ctttatccat tctcaaagtt tttatatctg gaaaaatata
    13621 ttttaattcc tcttcaattt tttgagttcc aactccaaat ggcttaacat aagtactttt
    13681 acattcagga cactcttttg gaatttcttt ctcatatcca caatagtggc atcttccagt
    13741 attgcttttc ttatgataag ttaaagatat atcacaattt tcacattgaa acacatatcc
    13801 acactttcta caagatacaa aatttgcata acctcttctg tttaaaaata gtatcacttg
    13861 attattttct tcaatcgcat aacgtatttc tttttgtaat ttcaaactaa atatacttct
    13921 atttccttta tctaattcat ctttcatgtc taccacttca atgtttggaa gaggcttatc
    13981 atttgctcta ctttttatat ttataagttt gtattctcca gattttgccc tataatactc
    14041 ttcaattgag ggcgttgctg aacctaaaat aagagttata ttatttttta atgccataaa
    14101 tctagcaact tctatagcat taaattttgg attcttctca gacttatatg atgactcatg
    14161 acattcatca attattatta agcctaagga attaaaaggt gcaaataaag ctgacctagc
    14221 tccaattaac actcttactt tacctgcttt gacagctttg taaacatcat gtttttctcc
    14281 ttcagatagt ttactgtgga acactccaac taaatctcca aacctactct ttagcctatc
    14341 tattgtttga ggagttaatg ctatctcagg tactaagaat atactgtcta agccttgatt
    14401 tagagcaaat tctattattt ccatgtaaac ttcagttttt ccacttccag ttactccatg
    14461 aattaagtat ggttttttat catctacaaa catattcgac tttatctcat caactgcttc
    14521 ttgttgttca ttgtttaatt ttatactttt tagtacggat ttgtaaatac tttttggctc
    14581 tctataataa tccttaaatt ctagggttat tagctttttc ttacttagag aatttatact
    14641 ttgttttgaa gcatttaata aatccaataa atcatttatc tctacatttt cattattttt
    14701 aagaaaactt aatatctctt tttgtttact tcccacattt attttatttt gctctatata
    14761 atcgtcaatc ttatcacttt ctaaactcaa agatatataa catactttct tttcattttt
    14821 gtgattttta tattcccaac ataattttat aattccattt ttattcattg tgtacaaaga
    14881 actatttaag tttggtatat attttaactt atcaacctta attttacctt tactatcaat
    14941 cactttctct actatttctc tatttttatc acttaaagtt gatatttttt ccttcaattc
    15001 aatctcattt aatccactta aactttcacc taataggact actttataat tatttaattt
    15061 gtatcccttt ggatatatca aatttataca ttctatataa gtacacaaat atctattttt
    15121 catccaataa accaactcta aatcttcttt tctaaatatt ggattttcat ctaatatatc
    15181 aataatttct tttattttta ttttttcatc taagctatct gtaaattgaa atacaaaggc
    15241 ttctgttggt ttattacctt ttccaaatgg tactaatatt ctgtgcccga tttttattac
    15301 atcagataaa aatacaggaa tttgatatgt aaataaatta tctgtatata tagtattact
    15361 tctaactatt acctttgcat attttttcat tataaaacct ctacttaaat ttaatatatt
    15421 gttcatattt taatatactt tacaagatat taaaatctca gaatttataa gcaatttcaa
    15481 gttattaata ttaactttat tttaataatt aactattaat tatattttat actttatgac
    15541 aaaataaatg ctgaaaacta caatttaact gacatttgcg agtttttact cgctaaaatt
    15601 aaattgcagc tttcagccac tttagctgtg ataaaataca caaatatcat atttaaaaaa
    15661 ggtcttattt ctcaagcaac gctttaactt tatctaaaat aacattggct acttcttctt
    15721 ttttcatctt aggatactca gtaatatttc cctctacatc tattattttt acaatattag
    15781 tatcagctct aaaaccagca ccttctttag ttaaatcatt tgccacaata aaatctaaat
    15841 ttttcttttt tatttttcct ttggcatgtt ctataaggtc attagtttca gctgcaaatc
    15901 caattagtat cttatcttct tttatttttc ctatttcata agcaatatca taatttctac
    15961 ttagttctat tgataaatca tcattcttct ttttaatttt tttgtcagaa taagtttttg
    16021 gtttataatc tgcaactgct gcactttgaa ttactatttt attttcactt aaatttgata
    16081 ctactgcttc atacaaatct tgtgctgact ctatttgaac aaatttttta agattttgtg
    16141 gaatagaaag atttgtagga cctgatatta atgttacatc agcacctcta gctatagctt
    16201 ctcttgctat agaatatccc attttaccag aagacctatt agttaaatat cttactgggt
    16261 ctatactctc tacagttgga ccagctgtaa ctatcatact ttgacctttt aaatcttgct
    16321 ctttagtaag attagtcaaa acttcctcta ctattatgtc tggattagct aatttgcctg
    16381 ttccaatatc tccacatgca agcctcccac tttctggttc aataaattta tatccaaagc
    16441 tctttaaagt ttgtatattt ttttgaacaa ttggattttc atacatatta gtattcatag
    16501 ctggtgctat aagaacctgt gctttggttg ccataacagt agttgtcaac atatcgtcag
    16561 ctataccatt tgcaatcttg cctataacat ttgcacttgc tggaactatt aagaataaat
    16621 ctgctttttt tgctaatgat atatgttcaa cttcccaagt ttttggttct tcaaacatat
    16681 cttctactac ataattttga ctcagcgatt gaaatgcaag tggtttaaca aattctgttg
    16741 ctgattttgt cattataaca tggatatttg catttagttt ttttaactta cttacaacat
    16801 cacaagcctt atatgcagct ataccgccac ttatgccaat tacaacagtt ttatctttta
    16861 gcatgacctt actcctcttc tgaaatttgt tggtgttgct cagcatgatg tctagcttct
    16921 tctatctcta tttcctcttc tgtcaataat ctatatgtta tttttccact tgcaacttct
    16981 ttagttgcta cacatacagg cttttcctta gttttatttg aaacatatgg ttcttctcca
    17041 tcaattaatt ttcttgctct ctttgaaaca gtccctacta aatagtatct gttgtctatt
    17101 ttttctagta cctcattgat agatggtttt aacataatta taattcctcc ttaaatttct
    17161 ctattataat atttttatat ctgctaactt tattcttttc agatgatatt ataccttcta
    17221 tttctttagc agatgttttt acatcttcat taaatataaa ataatcataa tccttaatca
    17281 ttttaatttc ttcatatgca cagctaaatc tcttctctat ttcagcttct gtttctgtac
    17341 ctcttccaac aattctattt tttaattctt caagtgatgg tggtagtaca aatataaata
    17401 ctccctctgg gcaaacttct tttatttgtt ttgctccttg catttcaatc tccagtaata
    17461 catcttgtcc tttttctaaa cattccatta ttgccgcttt tggagttcca taaaaattat
    17521 cataaatttg agcatactcc aaaaactcac ctttttctat catctcttca aacttttcct
    17581 tacttatgaa gaaataattt actccatcaa cttctccagt tctgggtttt cttgtagtag
    17641 ctgatacaga aagttttatt gtatcatttt ctttaagtag ttctttgcaa atagtacctt
    17701 ttcctgcacc tgatggtcct gatacaacta gcaataatcc ttttttcaca aacatttaag
    17761 cattcccctt ctaatattgt attcttactc tatattttgt atttgttctc ttattttttc
    17821 caattcgctt tttacttcta ctactaaatt agttatattt atatcagatg acttcgaacc
    17881 tatagtgtta gtttctctat tcatctcttg tattaagaaa tctatttttc tacctataga
    17941 gtcgtcttta aatatagtat ttttaagttg ccctatatga cttttaaatc taactatttc
    18001 ttctgttata ctgcttttat ctgcatatat tgcaacttct tgtgctaatc tattctcatc
    18061 tattatactt gggtcatcca gtaattcact tattctcaaa ttcaattttt ctctataatc
    18121 ttctacaaca ctacttgaat atttttcaat ctcttctata tgatttttta ataaatcaca
    18181 tctcatggca atatcttcag ctaatttttt accttcttca cttctcattt ctcttaattt
    18241 gattaatgca tcttcaactg cttgattcaa cattgaccac aataaatctt catcttcttc
    18301 cttttcttct attttcacaa tatcaggaaa ctttgcaaca ttcataacgc taatatcatc
    18361 tataatatca aatttatttt ttatttcttt tagtatgtct atatactgag atgctaatcc
    18421 ctcatcaaaa tttaagttta catcttcttt gcctaataag tcaaacttta tgtataaatc
    18481 tactcttcct ctttttacat aattttttac taaatttcta actttatcct ctaaaaatga
    18541 aatttttctt ggaagacgta tgtttatatc tgaatactta tgatttatcg ttttacactc
    18601 tactaaaaag taataattat catccttgta ttctcctctt ccaaaaccag tcatacttat
    18661 agccattaat taaacctcca aaacaccttc acatattttt actgctggac ctgtcatata
    18721 agagaaatct cctacatcta ttttaactgt tccaccttga gacgttacat ttacactact
    18781 ttctaccata ttaagtaaat tgcacactat tgctgatgca gtcataccag taccacaacc
    18841 taaagtatat ccacaacctc tttcccaagt ataaacatgt atattatact tatcttctac
    18901 ctttacaaaa tttacattcg ttttttcagg aaatatttta ttattttcaa tctcttttcc
    18961 atatttacaa acatcatcta catctaattc atctactata actactgtat gaggaacccc
    19021 catcaacata gaagtaactt taagctccct atctaaaacc tttatacttt cttgcacaaa
    19081 acgttcttta tttgtaagta caggaacatc cttagctata aaacttcctt ttcccatatt
    19141 gactcttata gagtttattt ctctattggt aagatttatt tttatatctt ttataccatc
    19201 taatgtatct actgtaaaac tttctttttt aactatacaa ttatcataaa caaatttaca
    19261 aaaacatcta aggccatttc cacacatagc tgctcttgaa ccatcagaat tataatatac
    19321 catttctaca tctgcaactt ttgaatcttt cacaactaac aatccatccg ctcctacaga
    19381 aaatcttcta tggcatactt tttttgctaa agcagtataa tcagatggat ttatctggtc
    19441 gaatcttcca tctattgcta taaaatcatt tcctattcca tgtagtttcc aaaatttcat
    19501 aagtatcgct ccttcgtaaa ttaacgctta aactattata acataaaaaa attcccataa
    19561 acttataatt tatgggaaaa gttttgtaat gacaactata atttgaggat gtgagggaga
    19621 gttgtcatta caattagggt aattatatta tgtttttaag ctagttcttt ctatgtttat
    19681 atattaatat ttctatatga attttatgta tgttttattt aaactgtcta tgaatttttt
    19741 aattaaacat ctggtaacca gctataatcc ttttagtaga tatctattaa catacaccta
    19801 ttaattcttt aagtgttttt aaaacatagt ctaaatcttc cttagtaata tctacatgag
    19861 ttacaaatct atattcacca ttttccattt tattaatttt tatatttctt tcaaaaaatt
    19921 cttttattaa aacatcctct tttataatat cttcactcat cttaaaaaat accatactta
    19981 tatctggatt aacattgttt acttcaatgc catcaatttt atttaattca caagctaaat
    20041 attttgcatt ttcatggtct tcattcaatc ttaaagtcat tttttcaatg gcaattatac
    20101 cagctgctgc aactatacct acttgtctca ttcccccacc cataactttt tgctttcttc
    20161 tagcttttgc tataaattct ttacttccag caagtataga acccattggt gcagctaaac
    20221 cttttgacac acagaacata acactatcac aacactttgc tatttcttta gcttctacac
    20281 ccaaagttaa tgctgcgtta aataatcttg ctccatctaa atgtactggt aagttgtgtt
    20341 tctcagctat ttttttaatt tctcttaaat tatcaagact cacaacagtt ccacctgaat
    20401 atgcattttc tacacatata agccctgtct gtggttcatg tatgtcatct cttctaattg
    20461 ccttttcaac aagttcagga tttagagctc cactttcgtc ttcatctata gttctaagct
    20521 gaactccagc tattacagca ggtgccccaa cctcatgagt tacaatgtga taacctttac
    20581 caataattat ttcttgccct cttaggcaat gagtaaatag agctaattga ttcccaaaag
    20641 ttccacttgg aaggaaaata gcatcttctt ttccaacttt agctgctgct aattcttcaa
    20701 gtttatttac agtagggtca tctctaaaga ttgaatctcc aacaggagcc tttgccatag
    20761 cttctctcat ttcgtcagta ggcatagtaa cagtatcact tcttaaatcg ataaatctca
    20821 ttttttcaac cttctttcat atttatatac tatagaacct taaaattgat tttttctgta
    20881 aagttcatat actttcatag cttatactct acacaataat tatactatat ttactttata
    20941 tttaatctac tttaaattat taattttaaa aataaagttt cctctctaat aagtataaat
    21001 aattatacaa tttaaatatt aatctctatc gtttaaattc cccctagtca caaagcgtat
    21061 attatgtgta taattaattt actgactcat tttggtcaaa gaaaggggtg ctataaatgg
    21121 cattagatgg attagttata cattcaatag tcgatgaatt atcatcaaaa cttacaggtg
    21181 gaaaaataga taagatacat caacctgaag atgatgaggt aatttttaat ataagaaata
    21241 ataaagaaaa ttttagattg gttttaagtg caagtgcctc aaatcctaga gtttatctta
    21301 caagtaatta tcaaaaagaa aaccctctaa aagcgcctat gttttgtatg ttacttagaa
    21361 aatacataca aggtggaaat atagtagaaa tttctcaaat aggttttgaa agaataataa
    21421 aaataagtgt tgaatcttta gatgaattaa aagaaaagac agttaaaaat attatgattg
    21481 aaattatggg aagacatagc aacataataa taactcatgg tgaagaaaat aaaattatag
    21541 attctataaa aagagtccct tttagcataa gtagagttcg tcaagtttta cctggtcatg
    21601 attattcatt accaccagaa caaaacaaac tcaaccctct tgatgatata tctaaggatt
    21661 tgtttattaa aaacctagaa gaattggaag gacctatctt taagtctata tattctaaat
    21721 ttctaggtat aagccctatt atagctaaag aaatttgcta cagagcaggt gtaaatcaaa
    21781 atgctatcat aaaggatata tctgatgaac aatttgattc tttacacaaa gtattttgta
    21841 atttattcaa tgatataaat tctaacaaat actccccttg cattattata gataaaaagg
    21901 tggataaggt agttgatttc agttgtataa accttacatt atttagcgat ttatcatata
    21961 taaataagga tagtatgtct cgtattctag aagatttcta tagaactaaa gatattaaag
    22021 acagaattaa tcaacgttca tctgatttaa agaagagtat atctgttaag cttgatagac
    22081 tttataataa acttaaaaaa caagaagaag aattatcaga atccgaaaat gcagacattt
    22141 ataagataaa aggagaattg attacttcat atatttatat ggtagaaaaa ggtatggaaa
    22201 gtattgaaat tgctaacttc tatgatgaaa attgtaatga tgtaacaata gaattaaata
    22261 aaaacttgac accatctgaa aatgctcaaa aatactttaa aaagtataac aaaatgaaac
    22321 atgctaaagt cgagatatct catcaaattt ccttaaataa ggaagaaata gattacttag
    22381 aaaacatagt tttaagtatt gaaaactgcg aaaatttagc tgaattacaa gatataaaag
    22441 aagaacttgc taaggttgga tatatcaaga ctcaaaagaa aaacagtaaa aaggatacta
    22501 tcccatctac aaaacctcat gaatttgtgt cttctgatgg atttaaaata ttggttggta
    22561 aaaacaataa gcaaaatgac tatcttacac taagacttgc tgataatgat gacttatgga
    22621 tgcatacaaa gaatattcct ggttctcatg taataataaa gtgtgctggt aaggaagtcc
    22681 ctgataatac tgtatttgaa ggagctatgc tagcagcatt ctttagtaag tcaaaacttt
    22741 cttctcaggt gcctgtagac tatactaaga gaaaaaatgt gaaaaaacct agtggttcta
    22801 aaccaggtat ggttatttat gaaactaaca gtactattta tgttactcct gaagaagaaa
    22861 cagtagccaa gcttaaggtt aaatctgaat aaattctgca ctaaatacaa aataaatgtt
    22921 agacaagcac acattatcat tctaaataaa aatagtggcc ttcttataaa gtacaataat
    22981 aaggccactt tctaattagc ttacttttaa ttttctaaca aaatactttt ctgttttaat
    23041 aactatactt atattcccaa caaatatttt cagtcttctt atatagatgt aattaaaaag
    23101 ttaacactaa aagctatttt ttaatttagt gatttgtttt agtaattcat tatattctga
    23161 ttcatacaat tcttttttta gattatcttt ttctatagat aacatagata taacagttgt
    23221 aagtctattt tctaatacta gaagattctc ttttttgatt tgcttgtctc tactaggagt
    23281 ttttttattt ctgctaatta tatattcgtc ataattacaa tcaaactccc ttattttagc
    23341 atcttttatc tctataatat agttacaaat atgtgataca aatactctat catgagacac
    23401 tataagcata gttttatcag tatttatcag tgccttttcc agtgcttcca tagattttat
    23461 atctaagtaa tttgttggtt catcaaatac taaaaaatta ttatcttcca atattatttt
    23521 acatagtgct atttttacct tttctccacc actaagtact tttacttttt tgtagacatc
    23581 atcaccttta aacccaaata ggcttaagtt tatccttata aaagattcat caaatgaact
    23641 attaacttta gtattgtata gaacactctt ttcctcatct aataaacttt gattttggtc
    23701 aaaacaacct acttttacct tgttatttat ttttatattg tcatttttat cagccaatat
    23761 ttcttttatc agagtacttt ttccacaccc attatcacct aataatgcta tctttttacc
    23821 tctttttatc ttaaaggaaa cattatctaa caagagctta ttttctaact ttagagtcat
    23881 atcttttacc tctaatagat ttttgctaat tatctccata ccatcttgaa tcttaatgtt
    23941 catttcttta gaaactttag gtttattctt tacctcaagt ttatcaattc tgctttttat
    24001 agccttcaca tttgagtcca actttttctt attagtctga ccacccattt tgtgcaacct
    24061 agcttctgaa ttacccattc tttttggtgt ctttcttatg ccatcactta aagctttttt
    24121 atataaaaga gctttttcaa gccttttttt ctctttaaca tattcttgat actcaaaatc
    24181 agctcttttt acttcttcat ctttttgcat taaataatca gtgtaattgc ctttgtaagc
    24241 ttttagtttt ccatcttcta gttctaatat agttgtacat aactcatcca gaaaacgtct
    24301 atcatgagat attaataata atgctccctc atgcctttta aacatatctt ccaaaagccc
    24361 aatgcttttt ttatctaagt ttgaagttgg ctcatcagct attatgatat ttttcttatt
    24421 actcagcgca tctgctattt ttaacttaac cttttcccct cctgataagt attcttcaaa
    24481 tttatctgga gcatttaaaa gactcttctc cttactatga ctacatgttt caatattatt
    24541 ttcactctga cttatataag aatagctttc tgtaaggtaa gtatatcctt catcaatttc
    24601 tatttcaccc aatattgctt ttaataatgt tgtttttcct tgaccatttg aaccaactag
    24661 acctattttg tcattttcta atatttcaag tttatctata tccaaaatta atttatctgc
    24721 ataatatttc tttaaattct ctacttttac taacaacata aaaaatccct ccttaacaca
    24781 cttaaatata aggagagatt ctataaatag gcataacaaa taaacgtata gactataatc
    24841 tactctcctt aatttaagca ttgcaaataa agccatcaaa ataggctttt caaaaattac
    24901 aatactttaa attataaaaa atagattata ttctcattgt cctagttacc ttgccctttc
    24961 tttcatttat ttttaatcat tatatcaaca ttaattacaa atgtctatag aaaattaact
    25021 aattttagtt attcaatata caatttattc tttaaattta ttcttcttca actttaaaat
    25081 cctgattatt taaaattctg tttaatacaa ttccaacaat tgcagctaaa ctaagaccag
    25141 ttatctttac tgtacttgtt atagggattc caatagaaat gcctttatta gataaatatg
    25201 ttgttccaag acctattaat aatataactg ctattattaa tatatttatc ttactttcta
    25261 cacaagaact gtcccttata gtttttaatc ctacataagt tatcattgaa aatagcatta
    25321 tactaattcc acccataact gaacctggta tactttgaag aaatccacca aactttccta
    25381 cacatgcaag caatatagca aatattgctg tacgtctaag tattgaaggg tcatagtttt
    25441 tagttatagc aagtactgct gtattttctc cataagttgt attggctggt cctcctaaac
    25501 accctgcaac tatagtcgca aatccatccc caagtaatgt tctatttaat cctggatttt
    25561 ctataaagtt tttacctact acagcaccat tagtagtcat atctcctata tgttccataa
    25621 atacagctaa tacaactgga gatataatca caattgctcc taaactgaac ttaggaactg
    25681 taaagttcgg tattgcaaat aaacttgctt ctgtaatagt agttatatct actaacctta
    25741 acagtaaaca gattatatac ccagaaaaaa cggctattaa tattcctaat tgttttataa
    25801 atcctctacc aaacttattg gttaaaattg ctattgctaa agttataaat gctattacaa
    25861 aattagctga agccatacta aaagctgttg gcaataaatt taatcctata actactatca
    25921 tagctcctgt aacttgtgca ggaaaatata atttaatttt atttacacca actattttta
    25981 ctataatcga cattataata taaattaatc ctgctactat tataccacct tgagcatatg
    26041 ctaaatctcc accatacgcc tctttagctg ctagtataac tggtataaac gcaaaacttg
    26101 aacctaaaaa ggcaggtact tttccttccg tacaaaaatg aaatatcaat gtaccaacac
    26161 cagcacagaa aattgcaact gacggattaa aacctgtcaa aatgggaact aatactgtcg
    26221 ctccaaacat ggctaataga tgttgtaaag acattattgt ttttttcata aaaacctcca
    26281 aaattattat atataaataa atcctctgtt taattaatat cttttaatta attatcattc
    26341 cctagattct attttttaac ctctatatac ttattatata atttatcatt attttacatt
    26401 ttacgacatc aaaaactcaa ataaaggaga ataaaaacta cattaagact cacatccata
    26461 aaattataat atttattttg tgcaatctat gtaagcttta tcctcctccc tgactattca
    26521 atgctaagct tttatataat acttaaaact aattattctt tgattgtaac tgaatcttct
    26581 ccatcaattt ctaataaact gacagatata atttcatgtc tagaagtagg tacatttttt
    26641 cctacataat ctgctcttat aggcaactct ctatgccctc tgtccactag aactgctaat
    26701 tgtattgatt taggtcttcc tatatctata atcgcatcta gtgaagctct cacagttctt
    26761 ccagtgtata aaacatcatc aaccaaaact actgtcttat catttacatt aaaatctaaa
    26821 taagttcctt taactacagg ttcaacatga attttttcca aatcatctct atataaagtt
    26881 atatcaatat ctcctgtatc tacttttgtt ccttctattt gttctatttt cttagaaatt
    26941 ctatttgcaa ttggcacacc tctagttttt attccaacta aaactagatt ttctacacct
    27001 ttatttcttt caattatttc atgacttatt ctagtaattg ctcttgctat tgccttttca
    27061 tccattaatt gagctttttc taccatatca taattattgt caaagatata atatatctat
    27121 ttgacaaatc tactcctttc ttttaatttt ttataaattt atttttattt aaaatttcaa
    27181 tttaaacaac aaaaaacttc tcatcacaag acaagaagct cttatataaa aaatatacag
    27241 tgtaatttag caattgtctt acgatatctc tgtatcgttt aaagataatt ttttaatcta
    27301 tcaactcaaa ttatatattt atatttcaaa tttttcaagc ttttttaaac aaaatacttt
    27361 aatataagat attttattta aatttcacta aatttattta cttatataaa aacaaaaaat
    27421 gatttataag tattatacaa atggttattt tatcttctta atagcttcct taaaatactc
    27481 aggtaattct gaattaaatt cgatatattc cttagtggta ggatgtataa atcccaactt
    27541 cttagcgtgc aaagtttgtc cttttaattt aaatttagtt tcttttggac catatacaaa
    27601 atcacctaaa agtgggtgat ttatagacaa agcatgaact cttatttgat gagttctacc
    27661 agtttcaagc ctagctctca tatgtgtaaa cttatcaaat ctttctacaa cttcaaaatg
    27721 agtaattgca ttttttccat cctttactac agccattttt aatctatcct taggatttct
    27781 ccctataggt ttatcaacag ttattttatc ttctttaacc acaccatagc atataaattc
    27841 atactctcta gttatagtat gttcctttaa ctgttctgct agaaaattat gtgcataatt
    27901 gttcttagct atcataagaa gaccagaagt atctttgtct attctatgaa ctataccagg
    27961 tctaataact ccatttattg acgacaactt atctttacaa tgatataaaa tcccatttac
    28021 tagtgtattt tcatagtttc caggagcggg atgaacaacc atatcctggg gtttatttat
    28081 tattaagaca tcatcatctt catatacaat atctattgga atatcttgag gtaaaacctc
    28141 taatacttta ggttctggta tctctataac aatattatct tcctctttaa ctagatattt
    28201 agctttttct actttattat tgacctttac ttttccatct tttataattt tttgtatata
    28261 acttcttgac atatcaccta attgttctgc tagataaata tcaagtctaa cttcttcttc
    28321 ctcttcaagt actaaaaact cttttacttc atccattata tcacctactt ttactttcaa
    28381 aaaataaaac atatatacat aaaaacacag ttcctacaac tacaaataca tcagctacat
    28441 tgaatacata ttcccatata actctaaagt cgaagtaatc taccacaaaa cctaatcgta
    28501 ctctatcaat tagatttcct aatgcaccag atataattaa tataattccc aaccttccaa
    28561 atatatgtac tttccttgta ttaagatagt ataatccaaa tactgttgca agtaatgcaa
    28621 caattataaa tatccactga ttattttgta ataatccaaa tgctgcacct ctattttcga
    28681 cataagttaa atgaaataca ttatttatta ttggtattgt tgaaacatct accaaattat
    28741 tcaataccca tattttagac agttggtcta agcctatgag tagaattatt attaatatat
    28801 atagcaatga tttttccccc tataaattat ttaaaaacca attttatttg aaacacacta
    28861 ttattattat acaaaaaaaa tgctctaaag agcaacttta ttaaaattgt attttcttaa
    28921 taaagctaga gcaaaattta aaatagtacc atctttttta tattgcagat tgctacatat
    28981 ttaaaatcat attattatgt ataaaaaatt taaaaataac atactaatta atactttttg
    29041 tgtgttttat agattaaaga ttaatgatgt ctgtacttta aacttacaag caccactaat
    29101 cttcaaacaa atatttttac ttttgcactt gcttattttt atctaaatgt tgtataagtt
    29161 cagatactgt tacgaattta tatcctctct cttttaattt aggaattact acttctaaag
    29221 cttgtatagt ttgtgattta tcatttcttt tagtgttata atcatgtaaa agtattatat
    29281 taccattttg gacctttgta agaatagtat ttataattgt atctacacca gggttagacc
    29341 aatctctagg gtctaagttt gaccaaagaa ttatattcat gcctttagaa actataatat
    29401 cacagacact tttactcatg gctctatatg gaggtctaaa tatctttggt tctactccta
    29461 ttacactttt tataatattt tgtgtatctg ttatttcttt ttcaacacta ccataactat
    29521 tttttgcaac atttatatgt gtaaatgtat gattccctat ttcatgcccc tcatcatatt
    29581 gcctttttaa taattctttg ttatattcta ctttttctcc aactacaaaa aaagttgctt
    29641 ttacattatt tttctttaat atatcaagta tttgtggtgt aaaatcctca tctggaccat
    29701 catcaaaagt caatgctaga atcttttcat cctcatttcc tttttttatt attacatctt
    29761 cataatcgtc ttttatattg tcatttaaag tataggtttc ttttgaacta ttttgattat
    29821 gtgtattatg gttatatgta tatacaccta ctatggataa taaacatata catatacccc
    29881 atattgcttt cttcatgtca ttacctcttt tctaattcat tctaacaata tatgatgtca
    29941 ggcttctaat ctctcaatgt tccattttta tttaaatcag ttaaatttgt taggtcttct
    30001 gaataaaagt tagaatcttc tacatcagga ttttgcattg catcacctaa taaagcattt
    30061 tctttttttg cacaattgtt acataaattt gtatcaggta atatatctaa tctttctaaa
    30121 tctatttgat tgtgacataa atcacaaaac ccatatgttc cattttctat tttagataat
    30181 gctgaatcta tttgatacag tcttccttct tcatgattta ttaaactatt ttgcatattt
    30241 tgcatatata aatccgttcc catatctcca atatgattgt cataactaga taattctcct
    30301 gatgaatatt tttcactagt atgtttagta gtgtctccaa acaaggtatt atctttcata
    30361 tctacgacta aattagttaa cttttctctt tcttttaata atttatcttt gtatttttta
    30421 gtatccattt tcaacacctc taattttaat atttatatca taaaaatagt atgtggaaaa
    30481 ctaaattaaa aatacaataa aaaacaagat ttgatttttt caaaaaaaat tgtaggtaaa
    30541 cttaaaattc acctacaaat tctttacata tatttttaat ataatgtttt tagtttttga
    30601 taataattac attaacttgc taatttatga gcattttgct cttttatatc cttagctttt
    30661 ttaaaaaata aaagtccaag gattattgca actacaatac ctattccatt agatatatta
    30721 actggaagtc taaatccttc ttttgcctgc attatataac taaatgttac tacagtcata
    30781 aaaagtgctg gcaatgtagt tatgtaatga tttttatttg ctttgactaa atatgcagaa
    30841 ccagtccaca acattatcat agcaagtgtt tgatttgccc aagagaaata tctccaaatt
    30901 atattaaaat ctataaatgt aagggcaacc cctacagcaa ataatggcaa agctattaaa
    30961 aatctatttt taactgcatc ttgattataa ttcattgcat cagctattgt taatctagca
    31021 cttctaaatg ctgtatcccc tgaagttata ggacatgcta caacaccaag tatggccaaa
    31081 gcgcctccaa taggtcccat taatccaaca gatactgtat ttacaacagt tgctgctcca
    31141 ccatcattaa atattacatt aagctgaggt ataccatgga aatatgacat agctgctgct
    31201 gcccaaacta aagctattat accttctgca accattgacc cataaaatac tggtcttgcc
    31261 tcactctctt tctcaacaca tctcgccata agtggtgatt gagttgcatg gaaacctgat
    31321 attgctccac atgctattgt tataaataag tatgggaata aaggtgttcc atttggattc
    31381 atattttgta aatttatatt tggtatgtta taccccttta ttattaatcc tccagctaca
    31441 cctactgcca taattaataa tgctgctcca aataaaggat atattttacc aatcaattta
    31501 tctattggta aaacagtagc cataatataa taaagtatta tcactccaac ccatatttgt
    31561 gcgtttacac ctgtcaatgt ctttaataat cctgctggac ctgttacaaa tacaactcca
    31621 accaatacta aaagaataac actaaatatt ctcattgcta tttttgcacc atttcctaga
    31681 taaagaccta ccaactctga tgcagatgta cctttgttct tcattgataa atatcctgaa
    31741 gcaaaatcgt gtactccacc tgcaaagatt gttccaaaca caatccacaa aaatgctgat
    31801 ggtccaaata acgccccttg tatagctcca aatatcggac ctaaccctgc tatatttaga
    31861 aactgaatta aaaagattct cttccatttc attggcacat aatctactcc atccctacaa
    31921 gctatagctg gagtttggtt tttgtcattg attccaaaaa ccttttctac aaaagtacca
    31981 tagataaaat aacctactat aagtactact attgaaccta aaaagcttac cataaattca
    32041 tccccttagt ttttatataa ttgctttata aatttttatg agtttaagaa aactatttcc
    32101 agttcaaata gtaatacttt tttatgctaa tataaatatt aattacatta agtgcatatt
    32161 taagtacatg aaatgacttt atatatgcat taacagccta aattctttta ctttgcttct
    32221 gcttacagtt acttcatagt cactattttt taatttcaat atgtatgtat tgttaaacca
    32281 tggtataatt tcttttactt tggttaaatt tacgatataa gacctatgtg ttctaaaaaa
    32341 tgttttatca tttataagat tctctacttc tgatatgcct tcttttaata taaacttttc
    32401 tttctcagta tatataaatg tctgcctttc attagcttca caataatata tatcatcaat
    32461 atctattaca accaatttat cacctttcca aaggctaatt ttatgtgtta tttcttctat
    32521 ctcctgattt actgtctctt ttttatattt atataaatta ctattgctat tagacagttc
    32581 aatatcactc atctcacttt tttctaattt attcaacata gaaataattc tctcttcaga
    32641 atatggcttc agtacataat caaatacatc taaagaaaaa gcatctactg cataattttc
    32701 atacgctgtt ataaaaacaa ttttaggcct tgatttaaac tgatttaatg tttttgcaag
    32761 aagcattcca tcgagatgag gtatatttat atccaaaaaa attacatcta ttttattttc
    32821 ctgaataaag tctaacactt ctataccatt agtaaattca tttactacct ctatgctact
    32881 tttattctca ataaaatatc ttaattcctt tcttgccgga aattcatctt ccactattat
    32941 agctctcata cttctactcc tttacataaa atactatcaa agtcccattg tctgttcttc
    33001 ttatattaag ccctcttcca tacatcagtt taagccttaa atgtacatta taaagtccaa
    33061 tcttattttc tggcatatta tcttgatata cattatttat aatttcctca cttataccta
    33121 taccattatc ctctattgat attctcacag tattttctaa tgaataaggt aactttttta
    33181 tggatatttt cactacacca gctctaccac tttctaaaat accatgtatt atcgcatttt
    33241 ccactaatgg ttgtataatc aaacttggaa tctttatatt tacatcttct atatcataag
    33301 atacagttag taattctcca aacctagctt tttctatctc tacaaaagat ttaacttgtt
    33361 caatctcttt atttatatca attaagttat cactatattc aagattatat cttagataag
    33421 ttgataaatt tattattaac tctctagcct tatctggact aaatcttata aatgaagcta
    33481 ttgtgtttag ggaattaaac aaaaaatgcg gattaatttg tctttgaagt gcttttattt
    33541 ctgctttatt tctcgcttct atatcttttt tatctttctc aatcccctct actatagata
    33601 taacaaatcc tattccaatc tgtccaacaa ttaaaggtaa atatatccca acaattattt
    33661 gaattgctaa agaatgtgga tatgatatta agtatataag tagtatagta aaactttcag
    33721 aaatcatacc taccaatata ccatacatta ctctatgttg ctttggtatc ctcttatata
    33781 gaaatcctga taatacacct gctagtatac ttgataaaag acatggaaca gatgttatcc
    33841 ccccaatatc cataaaatat ctatgaatcc ctgaaaaaac tcctgctgta atacctacca
    33901 ttggaccaaa taaaatgcca cctgatacta tagatattat tctagtgttt actattgacc
    33961 ccatataatt tataccacta taagttccaa atatggctaa aaaagtaaaa actaatgcta
    34021 tacagaccaa gtcattaaaa ctatattctt ccttttgaaa tatctgctta aatattttta
    34081 actttgttat tagaagaaac agtactacaa tgaggcttgt cttttctatt aatgcgatta
    34141 aaattgatgt tttcatattc cacctttaaa aaataaattt ttacacactc taaatttatt
    34201 atgtttgttg taacttatat atttgaagta atcctatctc gacattttcc acatttaacc
    34261 ttttaattaa ataaaaaatg gatatacttc tattaacaac taatactagc tgactaacac
    34321 aagcttgtaa taacttgtag ttatcattaa ctctacaatt ctagtattta attttatact
    34381 ttagaaatct cttttcttag aagtaatact ttcgaatatt atataataca atgttatgta
    34441 gattcttact catacaacat atttctttaa aaattttata ctattctttg ttcaaatatc
    34501 tcatttgatt taattgtgct aaacacacat tatcatctct ctgttatata tttattatat
    34561 agccgtatat cgataaagta aataaatcct atatttaaaa tcatatgttt gatagtaaat
    34621 cattataatg tatatttacc ataataattt gccaaccttg aaagtcactt ctataattag
    34681 aagttaaata attcttctaa aaaaaatacc tctaaatttt attttctgaa atacatagtt
    34741 ataactattt ttatcacgta taagaataaa aattccagaa aatttttatt atcta
//
LOCUS       DAMJYN010000037        33252 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.038, whole genome shotgun sequence.
ACCESSION   DAMJYN010000037 DAMJYN010000000
VERSION     DAMJYN010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 33252)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33252)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33252
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.038"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            211..351
                     /locus_tag="PC466_001951"
     CDS             211..351
                     /locus_tag="PC466_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769335.1"
                     /translation="MGIIESASKLAEMVHLLAVEKGITDIEAWDEAVKEYSKIYEERR
                     NE"
     gene            complement(526..846)
                     /locus_tag="PC466_001952"
     CDS             complement(526..846)
                     /locus_tag="PC466_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HDF2769336.1"
                     /translation="MKLKTISLPELNNLDPTLESTFIKMGEEQGELAECIGKFRNLSG
                     ENNDLDEVDIIKKTAKELMDVAQTCVTMMFKLEEQYGINLDEIRKEHIKKLEKRGYIK
                     NMDK"
     gene            complement(966..1703)
                     /locus_tag="PC466_001953"
     CDS             complement(966..1703)
                     /locus_tag="PC466_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HDF2769337.1"
                     /translation="MDANSLKDLIANHNNIVFFGGAGVSTESNIPDFRSSTGLFSQKL
                     NKQFTAEQLVSHTFFVRYPEEFFEFYKDKLIYPNAKPNNAHIALAKLEEMGKLKAVIT
                     QNIDGLHQMAGSKNVLELHGSVHRNYCTKCGKFFDLESMLNLGGNIPYCDNCGSIVKP
                     DVVLYEEALDSDVITKTISAISNADLLIIGGTSLAVYPAASFIDYYKGDYIALINKAN
                     TVYDKSASLVINKPIGEVLYEAVLRQI"
     gene            1918..3741
                     /gene="acd"
                     /locus_tag="PC466_001954"
     CDS             1918..3741
                     /gene="acd"
                     /locus_tag="PC466_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosaminidase"
                     /protein_id="HDF2769338.1"
                     /translation="MKKKAALATLAMLPLGVVNAHADGDIGIVTINYLNVRNEPTAES
                     SIAFVAKKDDKVLIKDSSNGWYKIKAESGQEGWASSKYIAKSNSDSLRTSTNKEKQVI
                     SNSLNMRNGAGTSYRVITVLKKGQKVEVISESNGWSKIKYDGRLGYVSSSYLGDVSNS
                     TNKSKTKQVNTTSLNVRSGPNTSYGLLGKLPKGSKVEVISESNGWSKIKYNGKDAYIS
                     SMYLSDVSQSNSDNSSQSNDKKNTDKVVNTASLNVRSGPGSTYSKLGKVYKGSKVTVL
                     SESSGWAKINFNNKEAFVVGNYLSTSADTSNNNSNSNSDNSSNSNGNNSSSSGQVNGM
                     SGISGAKIDYKSLSYTLESHISKQVEKAASGGNVIAPSNRKSTPSPEFSTFSAQRTSS
                     FVNASSSDIEYYLNPKNFTNTTKGMMQFLKINSYRDGISESSLNSYLNGLSSSVFKNQ
                     GAAFINAAKKYNIDVVYLVSHAMWETAYGKSTLAQGQTLTSYKGQPLSKPVKVYNFFG
                     IGAIDKSANVSGAEAAYSNGWTSVEATIDGSAKWISQNYVNSSKYNQNTIYKMKWNYD
                     YTWHQYATDVNWANGISGIMENLIGLYGGGSSLVFEVPQYK"
     gene            3956..8254
                     /locus_tag="PC466_001955"
     CDS             3956..8254
                     /locus_tag="PC466_001955"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HDF2769339.1"
                     /translation="MESIKEYLDKLEINNSGLGKQLKEVYINRVVYFKEDKIVYFYLT
                     SKDIVSHELLDKFKEELMYKLDYFKDMRMKIRFTGLERKSNKDVIKKYWNNILYILKY
                     LCPSIAGWYKQVEFLCLEEELKIKLPKGIFYERLMKKNVTYVLKTVLSEELGLDLNIT
                     IEKAVDEKVNKERLIRINDREMEEKIRALEIGKVNNCEENEEESYVIKSDVDENLIYG
                     DNANAMIENIVELNASSGTVAVVGDIFDVDTKELKNGKILMIASITDYTSSISCKLFL
                     TDTNKDGVLENVKKGAYLKIKGDIVYDTYQREISMMISGIRKETRIEREDKSEEKRVE
                     LHAHTQMSSMDAICSVKKLVERAAKWGHSAIAITDHGVVQGFPDAMNAGKSNNIKILY
                     GVEGYLVEDDSLIIEDANDKELSQTFVVFDIETTGFSNTNDKITEIGAVKIENFKIVD
                     RFSELINPEKDISYKIQELTGITNELIKDKPTIEEILPKFMEFVGDSVLVAHNAEFDT
                     GFISQKCREQGLLYNNKKVDTLMLARVMLPNLKRHRLNVVAKELGIPLLNHHRAVDDA
                     EATALIFNKFLQMLTEKGAKTLSDVNNILGKIDYTKLSTNHITLIAKNSIGIKNLYKI
                     ISDAHVNHFFRAPRILRSVLNEYKEGLIIGSACEAGVVFQAVKKNVSDEEMKKIIDLY
                     DYIEVMPIDNNRFMIDKGEVKDEEELRELNRKLIDTAKKFDKIPVATGDVHFLDKHEA
                     VLRKVLKYSQGFKVDEEETYLHFRTTDEMLEEFSYLGEELAYEVVVENSNLIADMVED
                     IKPIPDDTYPPIIEGSDVELREMCYKKAKRIYGDPIPEIVQKRLDRELNSIISNGYAV
                     MYIIAQKLVAKSLSDGYLVGSRGSVGSSFAATMSDITEVNPLPAHYICENEDCKYSFF
                     YEIGEWGSGVDLPDKDCPKCGRKLAKNGHDIPFEVFLGFEGDKEPDIDLNFSGNYQPT
                     IHKYTEELFGEGYVYRAGTIGTVAEKTAFGYARKYVEENNISVPNAEVLRLSNGCTGV
                     KRTSGQHPGGVMVIPDYKDVYDFTPIQYPANDTSCGVITTHFDYHSISGRILKLDILG
                     HDGPTIIRMLEDMTGINITEIPLDDKETMSLFTSTEALGVTPEEINCPIGCLAVPEFG
                     TKFVRQMLLDTKPTTFAELVRISGLSHGTDVWVNNAQDLVREDIVGLKDVISTRDDIM
                     NYLIFKGLPPKMSFTIMESVRKGKGLKPEHIEEMKKNNVPEWYIGSCKKIKYMFPKAH
                     AVAYVMTSFRIAYCKVHYPEAFYATYFTTKVEDFDADLIVKGLDAIKSKINEIESLGN
                     DATTKEKGMLTVLEVALEMYARGIKLLPVDIYKSDATEFIVVGEKTLLPPMAAIQGLG
                     GNAAINIQNERKNGEFISKEDLRKRTKISKTVIETLTNHGSLENMSERNQLSLF"
     gene            8458..8919
                     /locus_tag="PC466_001956"
     CDS             8458..8919
                     /locus_tag="PC466_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HDF2769340.1"
                     /translation="MKKNLEATIEEIVTKITDEHGFEMVDVEYVKEAGEYYLRVYIDK
                     EEGISLNECELVSRELSPILDEKDPIKENYFLEVSSPGLDRALKKDRDFVRYQGRDVD
                     LKLYKPLNGCKQFEGELVGLTEDNNIKIIANGKEMEFNRKDVAIVRLAIKF"
     gene            8949..10103
                     /gene="nusA"
                     /locus_tag="PC466_001957"
     CDS             8949..10103
                     /gene="nusA"
                     /locus_tag="PC466_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HDF2769341.1"
                     /translation="MNHEFMEALDELVVDRGIDKEILIDTIEQALLTAYKKNFGSAQN
                     VRVEFDRDKGDIKVFSQRVVVDESDLYDTFLEIELADAREINPNYELGDIIEHEVTPK
                     NFGRIAAQTAKQVVVQRIREAEREIVYNEFIEKENEIVTGEVARANKNVVYVNLGRIE
                     GIMTQSEQIPFENYKAGQKIKFYILEVKKTNKGPQIVVSRSHPGLVKRLFEEEVPEIY
                     EGIVQIKSVAREAGSRTKMAVKSIDEKIDPIGACVGPKGLRVKNIVDELGDEKIDIIK
                     YSEDPAEFISAALSPSKVVRVDIDEDEKSALVIVPDYQLSLAIGKEGQNARLAAKLTN
                     WKIDIKSESQAEQEMLNLENSKEIEAEDVEAEFIDQEELGTSEDNFSEEE"
     gene            10110..10391
                     /locus_tag="PC466_001958"
     CDS             10110..10391
                     /locus_tag="PC466_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HDF2769342.1"
                     /translation="MILKKVKKVPQRKCIACQDRDSKKELIRIVKNKEGKIFLDPTGR
                     ANGRGAYVCKSSECLKKAIKSKALNKAFKIDVPDEVYDNLLMELEEYEK"
     gene            10381..10692
                     /locus_tag="PC466_001959"
     CDS             10381..10692
                     /locus_tag="PC466_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal L7Ae/L30e/S12e/Gadd45 family protein"
                     /protein_id="HDF2769343.1"
                     /translation="MKNNKEKVLSFLGLATRAGKIVSGDDSTLLDLKKGKVNLILIAE
                     DASNNTKKLFKDKSTFRNIPYLFFSTKEEIGFAIGKSPRAVVGIKDENFSKKIIELIE
                     I"
     gene            10714..12654
                     /gene="infB"
                     /locus_tag="PC466_001960"
     CDS             10714..12654
                     /gene="infB"
                     /locus_tag="PC466_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HDF2769344.1"
                     /translation="MSKTRVYQIAEELNISNEELINKLAELDINVTDKDSVLEGEELE
                     LALEMLGEDLSQENGNVIEIDGKLTVQVLATKLDKSPSEIIMKLMKMGTMATINQEIS
                     FEIAALAAKDYGFELTVAESDDTEALEIEALMEIEEDKEEDLKPRPPVVTVMGHVDHG
                     KTSLLDAIRKTDVISGEAGGITQHIGASEVKINGHKIVFLDTPGHEAFTSMRARGAQV
                     TDIAILVVAADDGIMPQTVEAINHAKAAGVPLIVAINKIDKPGANPDKVKQELADQGL
                     LVEDWGGEVIAVPVSAKKKEGIDTLLEMVLLVAEMEELRANPNKRAVGTVIEAELDKG
                     RGPVATVLVQGGTLTVGDPIVAGVACGKVRAMINAKGKRVKTAGPSTAVEILGLSEVP
                     QGGDQFVEVPTDKIARSVAARRQQIVRDEMLKSTQRLSLDALFSQMSEGSIKDLNIVI
                     KADVQGSVQAVKQSLEKLSNEEVQVKVIHGGVGAVTESDILLAAASNAIIIGFNVRPV
                     PGAESLGEKENVDIRTYTIIYKAIEDIQAAMTGMLDPEYVDEETGKAEIREIYKISGV
                     GTVAGCYVTNGKIFRNCKVRLVRDSIIIHEGELAALKRFKDDVKEVNSGYECGMSFVN
                     YNDIKEGDIVEAYITKEVERKL"
     gene            12697..13077
                     /gene="rbfA"
                     /locus_tag="PC466_001961"
     CDS             12697..13077
                     /gene="rbfA"
                     /locus_tag="PC466_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HDF2769345.1"
                     /translation="MASYNRTRRIAEEIRKVVSTMLINGVKDPRITSMVSVTDVEVTN
                     DLRYAYVYVSILGGDEESTLTGLKSAGGYIRREVGKNIKLRYIPEIVFKLDDSIEKGM
                     YMDNLIKRVNEKNAQQNEDENYDE"
     gene            13058..14041
                     /locus_tag="PC466_001962"
     CDS             13058..14041
                     /locus_tag="PC466_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HDF2769346.1"
                     /translation="MKIMMNNMDSIINYIYEGDYFIVTSHISPDGDNVGSTLSMYYTL
                     KNLGKNVYYVLDDEAPLNLRFLVEGVKIYKSNEFNMKNYSLIALDCGDKMRICVSDEI
                     KNNASKLICIDHHASNDSYGDLNYVDIDASSTCELVYNLLVRFQQTKDINIINEDIAT
                     CLYTGLVTDTGNFSYSNVHASSFEMAKNLLVLGAQKNTIIQNIYQSNSSDYYKLLGEA
                     LKGLEIFDSKVSSIVLTQDMMNRNNISFNDVDGITTYTRDIKGIEVGILFKEKKQNEI
                     KVSFRSKNYVDVSEIAKLFGGGGHVRAAGCTIRDSIDNAKKMVLEAVLKSI"
     gene            14054..14959
                     /gene="truB"
                     /locus_tag="PC466_001963"
     CDS             14054..14959
                     /gene="truB"
                     /locus_tag="PC466_001963"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HDF2769347.1"
                     /translation="MNKIISILKPTGMTSHDVVSRVRKILNIKKVGHTGTLDPDASGV
                     LPICIGKATKVCEVILNKDKSYICELTLGISTDTYDASGEILKKVDDFKFSNEDIERA
                     FDTQRGEINQLPPIYSALKVNGKRMCDLVRSGRQSEITLKTRRVNIKDIKILSIKGNK
                     VMFYVECSKGTYVRSICHDIGEYLGCGAHMSFLNRTSSGKFDLDNSITLEELELFYEN
                     KTLDKYLYDIDYVLDSFNYVVLNPNAIKYYSNGGSIDDKRFLKNNFDKDDEVVRVYST
                     DNFLGLGKLSKHNNTISVKSDKMFI"
     gene            15090..16019
                     /locus_tag="PC466_001964"
     CDS             15090..16019
                     /locus_tag="PC466_001964"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HDF2769348.1"
                     /translation="MVIIKSIKEIANIKESVITIGNFDGVHKGHQVLIGKTVEYAKKE
                     NIQSIVFTFANHPVNYFRPNSTKNIISNDDKIKLLEDLGIDIVVIIPFDEYMTKIPAK
                     DFVDEILVKKLKAKKIVIGHDFTFARAKEGNVNLLKSLEHEFGFEVEVIKPIKINDVR
                     VSSTYIRSLVSQGDMANVKEYLGRNYKLEGCVIHSKHLGRTIGFPTANIDLKNNMLVP
                     KRGIYASIVHIGDETYFGATNVGYNPTVNGKTLSIETNILEFDRDIYGENIIVEFLER
                     IRDERKFNSIDDLKNQLYNDTNYVYENYVCKNK"
     gene            16123..16380
                     /gene="rpsO"
                     /locus_tag="PC466_001965"
     CDS             16123..16380
                     /gene="rpsO"
                     /locus_tag="PC466_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002843739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HDF2769349.1"
                     /translation="MINKSEIIKEYGRAEGDTGSPEVQIALLTARINELNGHLKTHKK
                     DHHSRRGLLKMVGRRRNLLAYLKEKDLEGYRALIAKLGLRK"
     gene            16620..17465
                     /locus_tag="PC466_001966"
     CDS             16620..17465
                     /locus_tag="PC466_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HDF2769350.1"
                     /translation="MKIKLVCDSLCDIPDEISEKDYIEIVPLTVIFNDREYIEGVDIK
                     KEEFYKKVKEIKQIPKTSQATYMEFKEVFDKFITEGYHIICMTGAANASGTFQSAMIA
                     KNDVNENEKIHIFDTRNLSLGSGQYVIKACELLEEGLGFEEIIDELENTRSSVRLLFA
                     PYTLDFLKQSGRVPVATALIGNMLNIKPIFFFDNGEAKLVNKVRGIKNIASKLVDIIL
                     EMNEGSLEGKIVTIGCGDNLHDCEILKDEVNKRIKARRVLFTRGGVSICSHTGPDILA
                     ISCSN"
     gene            17590..19701
                     /gene="pnp"
                     /locus_tag="PC466_001967"
     CDS             17590..19701
                     /gene="pnp"
                     /locus_tag="PC466_001967"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HDF2769351.1"
                     /translation="MFEHKIFKMDFAGRELSVEIGKICEMASGSCIVRYSDSMVMVNT
                     TKSAKPRDGIDFFPLSVDYEEKLYSVGKIPGGFLKREGKPSEKAILTSRLIDRPIRPL
                     FPKGFRNDVQVVATVLSVDQDCTPDIVAMIGSSIALSISDIPFNGPTGSVCVGLVDGA
                     FVVNPNAEQREKSSMHLVVSGTKEAIMMVEAGADEVPDEVMLDAILFAHQEIKKIVEF
                     IEGIVAEVGKEKMPVELYHAGEEITQLVREFATDKMKKAVQTFEKLERMENMDRVKEE
                     TLAHFEETLEDFEDFVGDIEEVLQDIIKEEVRKLIVHENVRPDNRKLEEIRPIWCETG
                     MIPRAHGSAIFTRGQTQVLNVATLGALGDVQKLDGLDEEENKRYMHHYNFPAYSVGEA
                     RPSRGPGRREIGHGALAERALLPVIPSQEEFPYAIRLVSEVLSSNGSTSQASVCGSTL
                     SLLDAGVPIKDMVAGIAMGLIKHDGKVAVLSDIQGMEDHLGDMDFKVAGTEYGITAIQ
                     MDIKIDGIDKEILQRALKQAKEGRIHILGEMRKTISQPKPELSPYAPKIVKMQINPDK
                     IKDVIGPGGKIITKIIDETGVKIDIEQTGEVFISGIEIDMIKKAQELINNIVVEPEVG
                     KTYKGKVSRIMNFGAFVEILPGKEGLLHISHIAHERVAKVEDVLNIGDEVEVKVTEID
                     EKGRVNLSRKVLLPKPEHKNK"
     gene            19967..20710
                     /locus_tag="PC466_001968"
     CDS             19967..20710
                     /locus_tag="PC466_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HDF2769352.1"
                     /translation="MIMMVLNKSKLKKIIILILVVLLVLSGGVMVLKLFNNKPVFNLF
                     NGVDLPYERGTKDKSGYVALTCNIDLGWETEYVESILETLKKENVKITFNVTGKWAEK
                     NKDELLKIKKQGHEIGNHGYKHLDYSTLSYEDNYEQIETSKKIIEEIIGEKTKFFQAP
                     AGSFGPETVKAAKALGYTSIKWDADTIDWKYKDQPEVIIDRMKKKDIKDSSIILMHPT
                     NATTKCIDDIIAIVREKGLKPGKLSDVFK"
     gene            20868..22115
                     /locus_tag="PC466_001969"
     CDS             20868..22115
                     /locus_tag="PC466_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HDF2769353.1"
                     /translation="MYKTKILENGLTIIGEEIPYLKSITLGIWINAGSRIEEAQVSGT
                     SHFIEHMMFKGTKNRTSKEIASSIDNLGGQINAFTSKECTCYYVKLIDEHIDTGIDVL
                     SDMILNSKFDKNDIDKERLIILEELKMYEDSPDDLSYDLLVENIYANDGLGMNIIGTK
                     ESLYNITRESMLEYLNKYYIPNNAVISIAGNFNFDDMVEKIKSKFGHWEKKNLSIDIS
                     EAKFNPCFISKNKDTEQVNLAICLKGIPFENDEEVYSMAVVNNIFGGSISSRLFQKIR
                     EEKGLVYSIYSSQTLYRKCGELGIFASMSTENLQDVYNLIKKEIENIRENYLTEKEIS
                     ESKEQLKGNYILDLESTSSRMMSTGKSMLLSKKVKTTDEILECINNVNINSIKKVVDK
                     VFNIENIGTCIVGRDVEKILHLD"
     gene            22150..22395
                     /locus_tag="PC466_001970"
     CDS             22150..22395
                     /locus_tag="PC466_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlmC/YmxH family sporulation protein"
                     /protein_id="HDF2769354.1"
                     /translation="MNLSEIAGKEIVNLVTGERLGVIGECDLILDETTGGILALLIPK
                     EKGFFARRKDKSFLEVPWRNVKKIGNDMIIIEYEGYI"
     gene            22405..23628
                     /gene="dapG"
                     /locus_tag="PC466_001971"
     CDS             22405..23628
                     /gene="dapG"
                     /locus_tag="PC466_001971"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HDF2769355.1"
                     /translation="MSILVQKFGGTSVESYEKMNEVCKIVKAYKKNDEELQLVLVVSA
                     MGRKGAPYATDTLINLCSAVNDEPSKRELDLIMSCGEIISGTILANLLNAQGIDSVFF
                     TGQQAGIITSDEYSNAKIKYINPKKVKRALDDGKVVVIAGFQGVTDDGEITTLGRGGS
                     DTSAVAIGKALECETVEIYTDVDGIMTADPRVEPNAKVLSFIDYEEVFQMADKGAKVI
                     HPRAVQLAKSGNITLAIKNTMNPTFEGTKIGSLCRHLEENIEYEQERDFKVAVANKDS
                     VAQVKIKSAEEVFTEVLNEIEKKLITIDMINFFISEKAFVVEDADIKSLKEILDKFEL
                     DYEVNRDCAKVTLICSRIADEMSGIMSKVVRGLSKAGVSLLQTSDSNMTISCLVSEED
                     MHTAVHAIHQQFYLK"
     gene            23741..24475
                     /locus_tag="PC466_001972"
     CDS             23741..24475
                     /locus_tag="PC466_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit"
                     /protein_id="HDF2769356.1"
                     /translation="MKDYREDNERFDKDNCSEESSCEERECIKQFGTNEMPPQPPKDI
                     QCITIIGEIEGHFIGNPQKKATKYEHIIPMLYSIEESNDVKGVLVVLNTVGGDIEAGL
                     AIAELLNSTSKKVVTLVLGGSHSIGVPLATAGDYSFIAPTATMIIHPVRTTGLVIGIN
                     ETFEYFKKMQDRIIQFIIRTSNIKKDVLEKLMHEKDELVSDVGSVLIGKEAVDYGLID
                     EVGGLKEALKKLRELIKESEEEKNND"
     gene            24598..27009
                     /locus_tag="PC466_001973"
     CDS             24598..27009
                     /locus_tag="PC466_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HDF2769357.1"
                     /translation="MATKKKKKKKVNTLSFNAEYHNLITIFIGVFLLYSLNSNSMGWI
                     PVLMQNLFKGLFGGLSIAIPFIVIITGLLGFFDGNEYIYRLRKTKLYYIIILFIFVFY
                     GLLNAGTLPVDSPLKGNMFDDVMKLGVSGQGSGLIATTIAYYMSKIFGIAGGWLISIF
                     ALILSVMFIFNISIKDLVSNAKSKSKASKDSNLTFKDKIANMKKSAIDMMTDEVDDTT
                     INKKPGFFKGLMSKGLNNDDEEDEYFEEENSDGVDDKTIKIVGFNKAEDEYLEILEGT
                     QSMPELDVLKELQKATNENPVVDTKPEKKVDIAKSNLNIEKTQPMSIVAEPVNEDYSN
                     YKKPSIELLNKVNKKSDENGKKKVLKNASLLEKTLSDFGVEAKINQVTVGPTITRYEI
                     QPSPGVKVSKIVNLTDDIALSLAAKSIRIEAPIPGKSAIGIEVPNEEAQMVGVREVLE
                     SEEFNNFNSPLAMGLGKDVAGKIIIGDIGKMPHLLIAGSTGSGKSVCVNTLISSILYK
                     ANPDEVKLLLIDPKVVELANYNGIPHLLIPVVTDPKKAANALNWAVTEMNRRYKLFAD
                     AQVKDVTSYNEKAEEKLPKIVIIIDELADLMMASANDVEDYICRLAQMARAAGMHLIV
                     ATQRPSVDVITGVIKANIPSRIAFAVSSQTDSRTILDMGGAEKLLGKGDMLFYPLGAA
                     KPVRLQGAFISESESEKVIDFVKSQVKDGIKYEEDIIETISKVNTSKSSDEDEFLSEA
                     IEFVVESGQASASMLQRRFKIGFNRAARLIDSMEERGIIGASEGSKPRKVLISKQDLQ
                     NLEGE"
     gene            27012..28070
                     /gene="mnmH"
                     /locus_tag="PC466_001974"
     CDS             27012..28070
                     /gene="mnmH"
                     /locus_tag="PC466_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-selenouridine(34) synthase MnmH"
                     /protein_id="HDF2769358.1"
                     /translation="MSVIKIEKALKLDKVIFVDVRTEGEYEEDHILNAINMPLFKNNE
                     HNEVGTIYKMQGKHEAIQKGFDYVSYKLKDIYLQAAELALNYDNIVIYCARGGMRSGS
                     IVNLLSSLGVNVYQLEGGYKAYRNFVLEYLRHVMDTKNFVSVHGLTGTGKTDLLHLLD
                     EKGIDVLDLEGIAKNSGSTFGFITFDKKPPSQKNFETKLFESVFFSKENYIFVESESK
                     RVGSVTVPNEIFEAMTREGHHILLECDIENRVDRLCRDYIYDKDEGNILILKECINKF
                     RKRLGNKVVDDYIDLLESGEYKELVKRYLLEYYDPLYMHSVEKYKYSKIINFNDTQKA
                     LEDVIDLYESILEGESEC"
     gene            28064..29398
                     /gene="rimO"
                     /locus_tag="PC466_001975"
     CDS             28064..29398
                     /gene="rimO"
                     /locus_tag="PC466_001975"
                     /EC_number="2.8.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12 methylthiotransferase
                     RimO"
                     /protein_id="HDF2769359.1"
                     /translation="MLKIALESLGCSKNLVDAEIMMGILNNKGYKLIGDFEEADVIIV
                     NTCGFIESAKQESIDTIINFSELKKTGNLKLLIVTGCLAQRYSEELKTEIPEIDAIVG
                     TGSYQNIDKILKELSEMHQIVSLNDIEFVFNEDLPRYISTPSYMAYLKIGEGCSNNCT
                     YCIIPKLRGKYRSRKFEDIIKEAKKLAESGVKELVVIAQDTTKYGFDLYGKERLSELL
                     EELAKIDGFKWIRVMYSYPESITEELIQVIKKYDNICSYFDMPIQHASNNILKLMNRK
                     TTKEDILNKINLIRSNIPDAILRTTIIVGFPGETEDDFKQLVDFVEEVKFDRLGAFAY
                     SREEDTPADRLPNHIDEEVKIQRRDTLMMIQQKISEELNDKKIGKTYEVLIEEQIEDN
                     VYTGRTQGDAEEIDSIVYVKSVDNLEVGEFVSVQINDAMEYDLMGDVLYELA"
     gene            29385..29927
                     /gene="pgsA"
                     /locus_tag="PC466_001976"
     CDS             29385..29927
                     /gene="pgsA"
                     /locus_tag="PC466_001976"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HDF2769360.1"
                     /translation="MNLPNKLTLFRIFLIPVFVLIMLLNVPNKFLIACIIFIIASITD
                     ALDGKIARKYNLVTDFGKFMDPLADKLLVISALTCMIEDHLVSSWMVIIIVARELTVS
                     ILRAIAAADGKVIAAGNSGKLKTITQMVSIVFLLLGAQFENVLILNIGEILILIATLL
                     TLYSGWEYLYKNKELFMSSK"
     gene            30215..31261
                     /gene="recA"
                     /locus_tag="PC466_001977"
     CDS             30215..31261
                     /gene="recA"
                     /locus_tag="PC466_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HDF2769361.1"
                     /translation="MSVDQEKLKALNEALGKIEKDFGKGSVMKLGEATSMSIDVISTG
                     AIGLDIAIGIGGLPRGRIVEVYGPESSGKTTVALSCVASAQKDGGIAAFIDAEHALDP
                     VYAKALGVDVDNLIISQPDTGEQALEIAEALIRSGAIDIIVIDSVAALVPKAEIDGDM
                     GDSHVGLQARLMSQALRKLTGSIKKSNCVAIFINQLREKVGIMFGNPETTTGGRALKF
                     YSSVRLDVRKIDTIKQGDKVIGSRTRVKVVKNKVAPPFKQAEFDIMYGEGISKIGDLL
                     DIAADVDIVKKSGSWYSYNDTKLGQGRENVKKFLEDNLDLTTEIDEKVRAFYNLNEEH
                     EESGTSVSKEIVEE"
     gene            31437..32978
                     /gene="rny"
                     /locus_tag="PC466_001978"
     CDS             31437..32978
                     /gene="rny"
                     /locus_tag="PC466_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HDF2769362.1"
                     /translation="MDVIDSVVMIVIGAAVGIIAGYFVRKNISEAKIGQAENLAKEII
                     DKAHHDSETVQKEKLLEAKEEIHKWRTEAERENRERRTEVQKYEKRVVQKEEVLDRKL
                     QNLESKEVNLSEKLKVVEKKEEEVEVIKTQQLEKLESISGITSDKAKEIILTNAERDV
                     RREMSIMIKEIESQAKEEADKKSREIIGYAIQKCAADHVAETTVTVVSLPNDEMKGRI
                     IGREGRNIRTLETLTGIDLIIDDTPEAVILSGFDPIRREIARIALEKLIADGRIHPAR
                     IEEMVEKARKEVDNIIKEYGEQAAFETSVHGIHPELIRLLGRLNYRTSYGQNVLKHSI
                     EVAHIAGIMAAEIGADIRLAKRAGLLHDIGKAVDHEMEGTHVEIGMDLLRRYKESKEV
                     IHAMSTHHGDYEPQTVEAVLVTAADAISAARPGARRETLEAYIKRLEKLEEIANSYEG
                     VEKSFAIQAGREIRIMVKPEAINDEEIHLLARDMTKKIEDELEYPGQIKVSIIRETRA
                     IEYAK"
BASE COUNT        13473 a         3526 c         6351 g         9902 t
ORIGIN      
        1 ctcaatttaa tatataaaaa agataataat agttagactt tttatatgaa ttttaatagg
       61 taaaatatcc tattgttttg tagatatatc ctaattatgt caaaaaataa aaaaattttt
      121 atttattaga gtttttggaa ataataataa cagatattat aattaattaa cagtttttgt
      181 aagtatttga caatagagag ggtgtaacaa atgggaataa tagagtcagc atcaaaattg
      241 gctgagatgg ttcatttatt ggctgttgaa aaggggataa ctgatataga agcatgggat
      301 gaagctgtga aagaatacag caaaatttat gaagaaagaa gaaatgaata gaatgataaa
      361 aaatgaaaac ttgatgataa aaaataactt tatttaaaga aattcaattt ttatagaaat
      421 attaaaaata atataaataa aaagatggta tttcaaatgt aagtaaaaaa tcattttggg
      481 ataccatcct tattatttat tttaataata tataagtaat aaatcttact tatccatatt
      541 ttttatgtaa cctctttttt ctagcttttt tatatgctcc ttacgtattt catcaagatt
      601 aataccatat tgttcttcta gcttaaacat catagtaaca catgtctgag ctacatccat
      661 tagttcctta gcagttttct ttataatatc aacttcatct aaatcattat tttctccact
      721 tagatttctg aatttaccta tacattcagc taattcacct tgttcttcac ccattttgat
      781 aaatgtagat tctagtgttg ggtctaaatt attaagctct ggtaaagata tagtttttag
      841 tttcataaaa gctcctttca agttattcgt atttatacta aaacatcata acaaaaataa
      901 tactaaaaaa aaactttaaa ttcaacataa aaacttacat atataataaa aatcgtgaaa
      961 taaatctata tttgtcttaa tacagcctca tataaaactt ctccaatagg tttatttatt
     1021 acaagagaag ctgacttatc atagactgta tttgctttat taataagagc aatataatca
     1081 cctttgtaat aatctataaa acttgctgct gggtacacag ctaatgatgt acctcctata
     1141 atcaataaat cagcattact tatagcagaa attgttttag taatgacatc actgtcaaga
     1201 gcttcctcat aaagtactac atctggtttt actatagaac cacagttgtc acaataagga
     1261 atattacctc ccagatttaa catagattct aagtcaaaaa acttaccaca tttagtacaa
     1321 taatttctat gtacagaacc atgaagttct agcacatttt tacttccagc catttgatga
     1381 agtccatcaa tattttgagt tatgacagct ttaagcttac ccatttcctc gagttttgct
     1441 aaagctatat gagcattgtt gggttttgca ttaggatata ttaatttatc cttataaaat
     1501 tcaaaaaatt cttctggata tctaacaaaa aaagtatgtg aaactaattg ttcagcagta
     1561 aattgtttat tgagtttttg gctaaataat ccagtagaac ttctaaagtc tggaatatta
     1621 gattcagttg aaacacctgc tccaccaaaa aatacaatat tattgtgatt agctattaag
     1681 tcttttaagc tatttgcatc catagttaca cctccaaatt attatatata aattgtacta
     1741 catattaggt cttttatgtt ttattaattt aaataaatat gtagtttaat aagttaaata
     1801 aagggaatat aaataaaatg tatacagagt ataaatagac aatatttact aaaataacaa
     1861 gttgtcgtat aattatatta aaattgtttt agtgtataag aagggcgggg gaagtacgtg
     1921 aagaaaaaag cagctttagc aacattggct atgttaccct taggtgtggt aaatgcacat
     1981 gctgatggag atataggtat agtgactata aattatttaa atgtaagaaa tgagccaact
     2041 gccgaaagta gcatagcctt tgttgctaaa aaagatgata aagttttgat taaagactct
     2101 tctaatggat ggtataaaat aaaagctgaa tctggacaag aaggttgggc ttcatcaaaa
     2161 tatatagcaa aatcaaatag tgactcttta agaacgtcta caaataaaga aaaacaagtt
     2221 atttcaaata gtttaaatat gagaaatgga gcaggtacaa gttacagagt aataactgta
     2281 ctaaaaaaag gtcaaaaagt agaagtaata tcagagagta atggatggtc taaaatcaaa
     2341 tatgatggaa gactaggata tgtatctagc tcttatttag gagacgtttc aaattcaact
     2401 aataaatcaa aaactaaaca agtgaataca acttcactaa atgtaaggag tggaccaaat
     2461 acaagttatg gtttgttagg caagttgcca aaaggaagta aagtagaagt aatatcagaa
     2521 agtaatggat ggtccaaaat aaagtataat ggaaaagatg cctatatatc tagtatgtac
     2581 ttatcggatg taagtcaaag taattcagac aattctagtc aaagcaatga taaaaagaat
     2641 actgataagg ttgtaaatac agcttcttta aatgtaagaa gtggaccagg ttctacatat
     2701 agtaagttgg gaaaagttta taaaggaagt aaagtaactg tactatcaga aagtagtgga
     2761 tgggctaaga ttaattttaa caataaagaa gcatttgtag taggcaatta tttatctact
     2821 tcagcagata cttcaaataa taactcaaat agtaactctg ataacagttc taatagtaat
     2881 ggcaataatt cttcatcatc aggtcaagta aatggtatgt caggtataag tggggctaaa
     2941 attgattata aatctttgag ttatacttta gaatctcata taagtaaaca agttgagaaa
     3001 gcagcatcag gaggaaatgt gatagctcca agtaatagga aaagcactcc aagtcctgaa
     3061 tttagtactt tttcagctca aagaacaagc tcatttgtaa atgcaagttc aagtgatata
     3121 gaatattatt taaatcctaa aaattttaca aatactacta aaggtatgat gcagttttta
     3181 aagattaaca gttatagaga tggtatttca gaatcaagtc ttaactcgta tcttaatggt
     3241 ttatcttcta gtgtatttaa aaaccaggga gcagccttta taaatgctgc caagaagtat
     3301 aatatagatg ttgtatatct agtatctcat gctatgtggg aaactgctta tggtaagtct
     3361 acacttgccc aaggtcaaac attaacatct tataagggac aacctcttag taagccagtt
     3421 aaagtataca atttttttgg tataggagca atagataaaa gtgctaatgt ttcaggtgca
     3481 gaagcagcgt attccaatgg ctggactagt gtagaagcta caatagatgg ctctgcaaag
     3541 tggatatcac aaaattacgt aaatagttct aagtacaatc agaatactat ctacaagatg
     3601 aagtggaatt atgattatac atggcatcag tatgcaactg atgtaaactg ggctaatgga
     3661 atttctggaa ttatggaaaa tttaattggt ctttatggag gaggaagtag tttggttttt
     3721 gaagttcctc aatataagta atacataaat aaaaaatata gactatgggt agttttcatt
     3781 ttatttaaat tatctatagt ctttttgtat ataatttata atctgtaaat ttaatgttaa
     3841 caaaactttt atgttataat attaattcta agtaaatata agtgagtaat aggtagaaat
     3901 agataaaaag tggtaataat atatataaag ataattttga gaaaggagga tatatatgga
     3961 aagtattaag gaatatttgg ataagttaga aattaataat agtggtcttg gaaagcaact
     4021 taaagaagtt tatataaata gagtagttta ttttaaggaa gataagatag tttattttta
     4081 tctaacttct aaagatattg tttctcatga acttttagat aaatttaaag aagaattgat
     4141 gtataaactc gattatttta aagatatgag gatgaagata agatttactg gtcttgaaag
     4201 aaaatccaat aaagatgtta taaaaaaata ttggaataat atattgtata tattaaagta
     4261 tctttgtcca tctattgcag ggtggtataa acaagtagaa tttctttgtt tagaagaaga
     4321 attaaaaata aaacttccaa aaggtatatt ttatgagcga ttaatgaaaa aaaatgtaac
     4381 ttatgtactt aaaaccgtgc ttagcgaaga gttgggatta gatttaaata taacaataga
     4441 aaaagctgtt gatgaaaagg taaataaaga aagactcata agaatcaatg atagagaaat
     4501 ggaagaaaaa attagggctt tagaaattgg aaaagttaat aactgtgaag aaaatgaaga
     4561 ggaaagctat gtcattaagt ctgatgtaga tgaaaattta atctatggag ataatgcaaa
     4621 tgctatgatt gaaaatatag ttgaattaaa tgcatcttct ggaacagttg cagttgttgg
     4681 agatatattt gatgttgaca ctaaagaact taaaaacgga aaaatactta tgatagcttc
     4741 aattacagat tatactagct caataagctg taaacttttt ttaacagata caaataagga
     4801 tggagtactt gaaaatgtta aaaagggagc atacttaaaa atcaagggtg acatagttta
     4861 tgatacatat caaagagaaa ttagtatgat gattagtggg ataagaaaag aaactagaat
     4921 agagagagaa gataaatcag aggaaaaaag ggtagaactc catgcacata cacaaatgtc
     4981 ttctatggat gctatttgtt ctgttaaaaa gcttgtagag cgtgcagcca aatggggtca
     5041 ttctgctatt gctataacag accatggtgt tgtacaagga tttccagatg ctatgaatgc
     5101 aggtaagtca aataatataa aaatacttta tggagtagaa gggtacttgg ttgaagatga
     5161 ttctctcatt atagaggatg caaatgataa agaactttcg cagacatttg ttgtatttga
     5221 catagagaca actggttttt ctaatacaaa tgataaaata actgagattg gtgctgtaaa
     5281 aatagaaaac tttaagattg tagatagatt tagtgagtta ataaatcctg aaaaagatat
     5341 ttcctataag atacaggaat tgacaggaat aactaatgaa ttaattaaag acaagccaac
     5401 cattgaagaa attcttccta agtttatgga atttgttgga gatagtgtat tagtagcaca
     5461 taatgcagag tttgataccg gatttatatc gcaaaaatgt agggaacaag gcttgttata
     5521 taataacaaa aaagtagata cacttatgtt agcaagagta atgttgccaa acttaaaaag
     5581 acatagatta aatgtcgttg caaaagaact tggtattcct cttttaaatc accatagagc
     5641 agtggatgat gctgaggcta cagcacttat atttaataag tttttgcaga tgcttacaga
     5701 aaaaggtgca aaaactctaa gtgatgtaaa caatatactt ggaaagattg attacacaaa
     5761 gcttagcaca aatcatataa ccttgatagc aaaaaattct ataggtataa aaaatttata
     5821 taaaataatt tcagatgcac atgtaaatca tttttttaga gcaccaagaa tccttagaag
     5881 tgtattaaat gaatataaag aaggattaat aattggttcg gcttgtgaag ctggggtggt
     5941 ttttcaagct gtaaagaaaa acgtgtctga tgaggaaatg aaaaaaataa tagatttata
     6001 cgattatatt gaagtaatgc ctatagataa taatagattt atgattgata aaggagaagt
     6061 aaaggatgaa gaagagttaa gggagttgaa taggaaatta attgatacag ccaaaaaatt
     6121 tgacaaaatt ccagtagcta ctggggatgt tcatttttta gacaaacatg aagctgtctt
     6181 aagaaaagtt cttaaatatt ctcaaggttt taaagtagat gaagaagaaa cttatttaca
     6241 ttttagaaca acagatgaaa tgttggaaga gtttagttat cttggagaag aattggcata
     6301 tgaagttgta gttgaaaata gtaatctgat tgccgatatg gttgaagata taaaacctat
     6361 accagatgat acttatcctc caattataga gggctcagat gtggagttaa gagaaatgtg
     6421 ttacaaaaaa gccaaacgaa tctatggaga cccaatacca gaaatagttc aaaaaagact
     6481 ggatagagaa ttaaattcaa taataagcaa tgggtatgca gttatgtata ttatagctca
     6541 aaaactggtt gcaaaatctc tttcagatgg atatttagtt ggttcaagag gctcagttgg
     6601 ctcatctttt gcagctacta tgagtgatat aacagaagtt aatcctcttc cagcacatta
     6661 tatttgtgaa aacgaagact gtaaatattc attcttttat gaaataggtg aatggggctc
     6721 aggtgttgat ttaccagaca aggattgtcc aaagtgtgga agaaaacttg ctaaaaacgg
     6781 tcatgatatt ccatttgagg ttttcttagg ttttgaaggt gataaggaac cagatataga
     6841 cttaaatttc tcaggaaatt atcagccaac aattcataaa tacacagaag aactatttgg
     6901 agaggggtat gtatataggg ctgggactat aggtactgta gcagaaaaaa cagcttttgg
     6961 atacgcaaga aaatatgtgg aagaaaataa tataagtgta ccaaatgcag aagtacttag
     7021 gctttcaaat ggatgtactg gagtaaaaag aacctcagga caacatcctg gtggagttat
     7081 ggttatacca gactataaag atgtatacga ttttacacct atacagtatc cagcaaatga
     7141 tacttcttgt ggtgttataa ctactcactt tgattatcat tcaataagtg gtagaatact
     7201 taaacttgat atacttggac acgacggtcc taccattata aggatgcttg aagatatgac
     7261 tggaataaat ataacagaaa ttcctttaga tgataaagag actatgtctc tatttacatc
     7321 tacagaagca ttaggtgtta caccagaaga aataaactgt cctataggtt gccttgctgt
     7381 accagagttt ggaactaagt ttgtacgaca gatgttactt gacaccaaac ccactacatt
     7441 tgcagaactt gtgcgtatat ctggtctctc tcatgggaca gatgtttggg taaataatgc
     7501 acaagactta gttagagaag atatagttgg attaaaagat gttatatcta cacgagatga
     7561 cataatgaac tatttaatat ttaaaggatt acctcccaaa atgagtttta caataatgga
     7621 gagcgtaaga aaaggtaaag gtctaaaacc agaacacatt gaagaaatga aaaaaaataa
     7681 tgttccagaa tggtatatag gctcatgtaa aaagattaag tacatgttcc caaaagcaca
     7741 tgctgttgct tatgtaatga catcatttag aattgcatat tgtaaagttc actatccaga
     7801 agcattttat gcgacttatt ttacgacaaa agttgaggat tttgatgcag atttaattgt
     7861 taaaggatta gatgctataa aatcaaaaat aaatgaaatt gagtcactgg gaaatgatgc
     7921 aaccacaaaa gaaaaaggta tgttgaccgt tttagaagtt gctcttgaaa tgtatgctag
     7981 aggaataaaa ttattaccag ttgatatata taaatcagat gcaactgagt ttatagttgt
     8041 aggagaaaaa acattacttc caccaatggc agcaatacaa gggcttggag gaaatgcggc
     8101 tataaacatc caaaatgaaa gaaaaaatgg tgaatttata tcaaaagaag atttgagaaa
     8161 gagaacaaaa atatcaaaaa cggtaataga aactcttact aatcatggtt cacttgagaa
     8221 tatgagtgag agaaatcaat tgtcattgtt ttaagttagc ccaaaaagtt gcaaataaaa
     8281 gaattttatg atatcatagt atagaaaata gtatactttg cagaaactaa gagtgagaca
     8341 gctgttctca ctcttttatt ttaaatatat tattaaaaag ttggtttatt tttattaaat
     8401 atattttatt taagattata taaactaatc atttacaatt gaataggagg aactttaatg
     8461 aaaaaaaatt tagaagctac aattgaggag attgtaacta aaataacgga tgaacatgga
     8521 tttgaaatgg ttgatgttga atatgtaaaa gaagcaggag aatactactt aagagtatac
     8581 atagataaag aagaaggaat atctttaaat gaatgtgaat tagttagtag agaattaagt
     8641 ccaatactag atgaaaaaga ccctataaaa gaaaattact ttttagaggt atcttctcca
     8701 ggacttgata gagcattaaa aaaagacaga gattttgtta gatatcaagg tagagatgta
     8761 gatttaaaat tatataaacc attaaatgga tgtaagcaat ttgaaggtga acttgtagga
     8821 ttaacagaag ataataatat aaaaatcatt gcaaatggta aggaaatgga atttaataga
     8881 aaagatgttg ctattgtcag attagcaata aagttttagt ggtatattaa atagggagga
     8941 tataaaaaat gaatcatgaa tttatggaag cattagatga attagtagtt gacagaggta
     9001 tagataaaga aatacttata gatactatag aacaagctct tttaactgca tacaagaaaa
     9061 actttggttc agcacaaaat gttagagttg aatttgatag agacaaggga gatataaaag
     9121 tattttctca aagagttgtt gttgatgaat cagatttata tgatactttc ttagaaatag
     9181 agttagcgga tgctagagag ataaacccta attatgaatt aggtgatatt atagaacatg
     9241 aagttacacc taaaaacttt ggaagaattg cagctcaaac agcaaagcaa gtagttgttc
     9301 aaagaataag ggaagctgag agagaaatag tgtataatga atttatagaa aaagaaaatg
     9361 aaatagttac aggagaggtt gctagagcaa ataaaaatgt tgtttatgta aatcttggaa
     9421 gaatagaagg tataatgact caaagtgaac aaataccatt tgagaattat aaagcaggtc
     9481 aaaaaataaa attctatata cttgaagtta aaaagactaa caaaggacct caaatagttg
     9541 tatcaagaag tcatccgggt ctagtaaaga gattgtttga agaagaagtt cctgaaatat
     9601 atgaaggaat agttcaaata aaatctgtag caagagaagc agggtcaaga actaaaatgg
     9661 cagtaaaatc tatagatgaa aaaatagacc caattggagc ttgtgttgga ccaaaaggac
     9721 ttagagtaaa aaatatagtg gatgaacttg gcgatgagaa aatagatata ataaaatata
     9781 gtgaagaccc agcagagttt atatcagcag cacttagccc atcaaaagtt gttagagtag
     9841 atatagatga agatgaaaag tctgccttag taatcgttcc agattatcag ttatcgcttg
     9901 ctataggtaa agaaggtcaa aatgcaagac tagcagcaaa attgactaac tggaaaatag
     9961 atattaagag cgaatctcaa gcagaacaag aaatgttaaa tcttgaaaat tccaaagaaa
    10021 tagaagctga ggatgttgaa gctgaattta tcgaccaaga agagttaggt acttcagagg
    10081 ataattttag tgaagaagag taaggaggga tgattttgaa aaaagtaaaa aaagtgcctc
    10141 aaagaaaatg catagcatgt caagatagag actctaaaaa agagcttata agaatagtta
    10201 aaaataaaga aggaaaaata tttttagacc caacaggaag agccaatgga agaggagcat
    10261 atgtatgtaa aagctctgaa tgtctaaaaa aagctataaa gagtaaagca ttaaataaag
    10321 cttttaaaat agatgttcca gatgaagtct atgataatct acttatggag ttagaagaat
    10381 atgaaaaata ataaagaaaa agtactttcg ttcttagggc tcgcaactcg tgcagggaaa
    10441 atagtgtctg gtgatgattc aactttgctt gaccttaaaa aaggaaaagt aaatttgatt
    10501 ttaatcgcag aagatgcatc aaataatact aaaaaacttt ttaaagataa atcaactttt
    10561 agaaatattc catatctatt tttttcaaca aaagaggaaa taggatttgc aataggaaaa
    10621 tctccaagag cagttgtagg aataaaagat gaaaattttt ctaaaaagat aattgaacta
    10681 atagaaattt aaaataaaat agggggtgat cttgtgtcaa aaacaagagt ataccaaata
    10741 gcagaagaat taaatatatc aaatgaagag cttataaata agttagctga attagatata
    10801 aatgtaactg acaaagattc agtattagaa ggtgaagagt tagaattagc acttgaaatg
    10861 ttaggtgaag atttatctca agaaaatgga aatgttatag aaatagatgg aaagttgaca
    10921 gtacaagtat tagcaacgaa attagataaa tctccatcag aaataattat gaagcttatg
    10981 aaaatgggaa ctatggcaac aataaatcaa gagataagtt ttgagattgc tgctttggct
    11041 gccaaagact atggatttga attaacagta gctgaaagtg atgatacaga agctttagaa
    11101 atagaagctt taatggaaat tgaagaagat aaagaagagg atttaaaacc tagaccacca
    11161 gttgttacag ttatgggaca tgttgaccat ggtaagacat ctttactaga tgcaataaga
    11221 aaaactgatg tgatttcagg tgaagctgga ggaataactc agcatatagg tgcttcagaa
    11281 gttaaaatca atggacacaa aatagtattt ttagatactc caggacatga ggctttcaca
    11341 tcaatgagag caagaggagc acaagttaca gatatagcaa tattagtagt tgcagcagat
    11401 gatggtataa tgcctcaaac agttgaagct ataaaccatg ctaaagcagc aggtgtacct
    11461 ttaatagttg ctattaataa aatagataaa ccaggtgcaa acccagataa ggttaaacag
    11521 gaattagcag accaaggatt attagttgaa gactggggtg gagaagtaat agcagttcca
    11581 gtatcagcta agaaaaaaga aggaatagat acacttttag aaatggtatt attggttgct
    11641 gaaatggaag agttaagagc taatccaaat aaaagagcag taggaactgt tatagaagct
    11701 gagcttgata aaggaagagg gccagttgca acagtacttg ttcaaggtgg tactttaaca
    11761 gtaggtgacc caatcgttgc aggtgttgca tgtggtaaag ttagagcaat gataaatgca
    11821 aaaggtaaga gagtaaaaac agcaggacca tctacagcag ttgagatatt aggtctatca
    11881 gaagttccac aaggaggaga ccaatttgtc gaagttccaa ctgataagat tgctagaagt
    11941 gtagcagcaa gaagacaaca aatagttaga gatgaaatgt taaaatcaac tcaaagatta
    12001 tcactagatg ctctatttag tcaaatgagt gaaggttcta taaaagacct taatatagtt
    12061 ataaaagcag atgtacaagg ttcagtacag gcagttaaac aatctttaga aaaattatca
    12121 aatgaagaag ttcaagttaa agtaatacat ggtggtgttg gagctgtaac agaatcagac
    12181 atattacttg cagcagcttc taacgcaata ataataggat tcaatgtaag accagttcca
    12241 ggtgcagaat ctctaggaga aaaagaaaat gttgatataa gaacatatac tataatatac
    12301 aaggcaatag aagatataca agcggctatg actggtatgt tagaccctga atatgttgat
    12361 gaagaaacag gaaaagctga aataagagaa atatataaaa tatctggtgt tggaacagta
    12421 gctggatgtt atgtgactaa tggtaagata tttagaaatt gtaaagtaag attagttaga
    12481 gatagcataa taatacatga aggtgagctt gcagcactta agagatttaa agatgatgta
    12541 aaagaagtta attctggata cgaatgtggt atgagttttg taaattataa cgacataaaa
    12601 gaaggcgata tagtagaagc ttatataact aaagaagtag aaagaaaatt ataaattcgt
    12661 atcaaagaaa atcagttagt aaagaaggtc gatggtatgg catcatataa tagaacaaga
    12721 aggatagcag aagaaataag aaaagtcgta agtactatgc ttataaatgg agtaaaagac
    12781 cctagaataa catctatggt gagtgtaact gatgtagaag ttacaaatga cctaagatat
    12841 gcttatgtat atgtaagtat tctaggtgga gatgaagaat ccacactaac aggtcttaaa
    12901 agtgctggag gatatataag aagagaagta ggaaaaaata taaaacttag atatattcct
    12961 gagatagtat ttaaacttga tgattcaata gaaaaaggaa tgtatatgga taaccttata
    13021 aaaagagtta atgaaaaaaa tgctcaacaa aatgaggatg aaaattatga tgaataatat
    13081 ggatagtatt ataaactata tttatgaggg tgactatttt atagttacct ctcatatcag
    13141 tccagatgga gacaatgttg gttctacact ttcaatgtat tatacattga agaatttagg
    13201 aaaaaatgta tattatgtac ttgatgatga agctccatta aatttaaggt ttttggttga
    13261 aggtgtaaaa atctataagt ctaatgaatt taatatgaag aactattctt taattgcact
    13321 tgattgtggg gataagatga gaatatgtgt gagtgatgaa atcaaaaata atgcatcaaa
    13381 attaatctgt attgaccatc atgctagtaa tgattcatat ggagatttaa attatgtaga
    13441 tattgatgca tcttctacat gtgaactagt ttataattta ttggttagat ttcagcaaac
    13501 aaaagatatt aatattataa atgaagatat agcaacatgt ttatatacag gtcttgtaac
    13561 tgatactgga aacttttcgt attcaaatgt acatgcaagt agttttgaaa tggcaaaaaa
    13621 tttacttgtt ttaggtgcac aaaaaaatac tataatacaa aatatatatc aaagcaattc
    13681 ttctgattat tataaattat taggagaagc tctaaaaggt ttggagatat ttgattcaaa
    13741 ggtatctagt atagttttaa ctcaagacat gatgaataga aataatatta gctttaatga
    13801 tgttgatgga ataacaacat atacaagaga tataaaaggt atagaagttg gaattttatt
    13861 taaagagaaa aaacaaaatg aaattaaagt gagttttagg tcaaaaaatt atgttgatgt
    13921 aagtgaaata gccaagttat ttggcggtgg tggtcatgta agggctgctg gatgtactat
    13981 tagagatagt attgataatg caaagaaaat ggtactagag gcagtgttaa aatcaattta
    14041 aggtgacagt aaaatgaata agattataag tatattgaaa cccacaggta tgacatctca
    14101 tgatgttgta agtagagtga gaaagatttt aaatataaaa aaagttggtc atacaggtac
    14161 tcttgaccca gatgcttcag gtgttttacc aatctgtata gggaaagcta caaaagtatg
    14221 tgaagttatt ttaaacaaag ataaatcgta tatatgtgag cttactttag gtataagtac
    14281 agatacttat gatgcttcag gtgaaatttt aaaaaaagtt gatgatttta aatttagtaa
    14341 tgaagacata gaaagagctt ttgatacaca aagaggagag ataaatcaac ttcctccaat
    14401 ttattcagct ttaaaggtaa atggaaagag aatgtgtgat ttagtaagaa gtggtagaca
    14461 atctgaaatt actttaaaaa caagaagagt aaatataaaa gacataaaaa tactaagtat
    14521 aaaaggtaat aaagtaatgt tttatgttga gtgttctaaa gggacttatg tgagaagtat
    14581 ttgccatgat ataggagaat atctgggttg tggagctcat atgtcgtttt tgaatagaac
    14641 atcttctggt aaatttgact tagataattc aataacatta gaagaattag aattatttta
    14701 tgaaaataaa actttagaca aatacttata tgatatagat tatgtccttg attcgtttaa
    14761 ttatgttgta ttaaacccta atgctataaa atattatagt aatggtggct caatagatga
    14821 taaaaggttt ttaaaaaata atttcgataa agatgatgaa gttgtaagag tatacagtac
    14881 agataatttc ttaggattag gaaagttatc aaaacacaat aatacaataa gtgttaaaag
    14941 tgataagatg ttcatataac caatgtattt aaaaaaacaa caaaagagat agtactataa
    15001 taacttctat agtctatctc ttttacttat gctataatag tttgtgaata agttaagagt
    15061 aaattatatt ttagcgggga acatttatta tggtgattat aaaatctata aaagaaatag
    15121 caaacataaa agaaagtgtc attaccatag gaaattttga tggtgtacac aaaggacatc
    15181 aagttcttat aggaaaaaca gttgaatatg caaaaaaaga aaatatacag agtattgtat
    15241 ttacatttgc aaatcatcct gtaaattact ttagaccaaa ctcaacaaaa aatattataa
    15301 gcaatgatga taaaataaaa ttattagaag atttgggaat agatatagtt gtaatcatac
    15361 catttgatga gtatatgact aaaatacctg caaaggattt cgtagatgag atactagtaa
    15421 aaaaattaaa agctaaaaag atagtaattg gacatgactt tacatttgca agggcaaaag
    15481 aaggcaatgt taatctatta aaaagcttag aacatgaatt tggttttgag gtagaagtaa
    15541 taaaacccat caaaatcaat gatgtaagag tgagtagtac ttatattaga agtttagtat
    15601 cccagggtga tatggctaat gtcaaggaat atttgggtag aaattacaag ttagaaggtt
    15661 gtgttataca ttctaaacac cttggaagaa ctataggatt cccaacggca aatattgacc
    15721 ttaagaataa tatgctcgtt ccaaagagag gtatttatgc ttctattgta catattggag
    15781 atgagactta ttttggtgct acaaatgtag gctataaccc aacagttaat ggaaaaactt
    15841 tgtctattga aacaaatatt ttagagtttg atagagatat ttatggggaa aatataattg
    15901 ttgaattttt ggaaagaata agagatgaaa gaaagtttaa ttcaatagat gacttaaaaa
    15961 atcaattgta taatgataca aattatgtgt atgaaaacta tgtttgcaaa aacaagtaat
    16021 gtatgataaa atgattaagg aaaataacca ttactcggca tttgaatact ccaatcaatg
    16081 cttagtaata ggcgtttcta aaaaaatacg gaggtaatct aaatgataaa caaatcagaa
    16141 ataataaaag aatatggaag agctgaaggg gatactggtt ctccagaagt acaaatagct
    16201 ttattaacag ctagaataaa cgagttaaat ggacatttaa aaactcataa gaaagaccac
    16261 cattcaagaa gaggactatt aaaaatggtt ggtagaagaa gaaacttatt agcttactta
    16321 aaggaaaaag atcttgaagg atatagagca ttaatagcta aattaggatt aagaaagtaa
    16381 tttcattctt tataaaaaag caggtatagt gtatacctgc ttttttatag ttaattcatt
    16441 ataaagtaaa atagttaata ataaaagtag tttatatgtt ataaaaaatt ataaaatgaa
    16501 taatattggg taagaatatt aaaatagtat acaaatacat aatcaattta aaaggaaaga
    16561 caggataaat atagaaattt tataacagga taattagttg gaataaggag gatattattt
    16621 tgaaaataaa gttagtatgc gatagtttgt gcgatattcc agatgaaata tcagaaaaag
    16681 attatataga gatagttcca cttacagtta tttttaatga tagggaatat atagaaggag
    16741 tagatataaa gaaagaagag ttttataaaa aagtaaaaga aatcaagcaa atacctaaaa
    16801 cttcacaagc tacatatatg gagtttaaag aagtgtttga taagttcata acagaaggtt
    16861 atcatataat ctgtatgaca ggggctgcaa acgcatcagg aacttttcaa agtgctatga
    16921 tagctaaaaa tgatgtaaat gaaaatgaaa aaatacatat atttgatact agaaatttat
    16981 ctctaggtag tggacaatat gttataaagg catgtgaact tcttgaagaa ggactgggat
    17041 ttgaagaaat tatagatgaa ttagaaaata ctcgcagtag tgtaagatta ctttttgcac
    17101 catatacact tgatttttta aagcagagtg gaagagttcc agttgcaact gctttgatag
    17161 gaaatatgtt aaatataaag cctatatttt tctttgataa tggggaagct aagttggtaa
    17221 ataaggttag aggaataaag aatatagcaa gtaaactggt cgatataatt ttagaaatga
    17281 atgaagggtc tttagaagga aaaatcgtca caataggttg tggagataat ttacacgatt
    17341 gtgaaatatt aaaagatgaa gtaaataaaa gaataaaagc aagaagagta ttatttactc
    17401 gaggaggagt ttctatttgc tctcatacag ggccagatat attggctata agttgttcta
    17461 attagtagta atataaggtt tttgcatata tatgtgaaga taattttata ttgttaattt
    17521 atagtatttt tgataatata gtaaatagag tgatatacgt gttttttaat aagaggagga
    17581 caagcattaa tgtttgaaca taaaatattt aaaatggatt ttgcaggaag agaactttct
    17641 gtagaaatag gaaagatttg tgaaatggct agtggtagtt gtatagttcg atacagtgac
    17701 agtatggtaa tggtaaatac aactaaatca gccaaaccta gagacggaat agactttttt
    17761 cctttaagtg tggattatga agaaaaatta tactctgtag gtaagatacc tggaggtttt
    17821 ttaaagagag aagggaagcc ttcagaaaaa gctatactta catcaagatt gatagataga
    17881 ccaataagac ctttattccc aaaaggattt agaaatgatg ttcaggtagt tgcaacagtt
    17941 ctatcagtag accaagattg tacaccagat atagtagcaa tgataggttc ttcaatagcc
    18001 ctttctatat cagacatacc atttaatgga ccaacaggtt cagtatgtgt tggccttgta
    18061 gatggtgcat ttgttgtaaa tccaaacgca gagcaaagag aaaaaagttc aatgcatcta
    18121 gttgtttcag gtacaaagga agcaataatg atggttgaag ccggagctga tgaagttcca
    18181 gatgaggtaa tgcttgatgc tattttattt gctcaccaag aaataaaaaa aatagttgag
    18241 tttatagaag gtatagttgc agaagttgga aaagaaaaaa tgcctgttga attataccat
    18301 gcaggagaag aaataactca attggttcgc gaatttgcaa ctgataagat gaaaaaagca
    18361 gttcagactt ttgaaaagtt agagagaatg gaaaatatgg atagagttaa agaagaaact
    18421 ttagctcact ttgaagaaac tttagaagat tttgaagatt ttgttggaga tatagaagaa
    18481 gtattacaag atataataaa agaagaagta agaaaactta tagtacatga aaatgtaaga
    18541 ccagataata gaaaacttga agaaataaga cctatatggt gtgaaactgg catgatacct
    18601 agagctcatg gttcagccat atttactaga ggacaaactc aagtacttaa tgttgctact
    18661 ttaggtgctt taggagatgt tcaaaaatta gatgggttag atgaagaaga aaacaagaga
    18721 tatatgcatc attataattt ccccgcatat agtgttggag aagctagacc atcaagagga
    18781 ccaggaagaa gagaaatagg acatggtgct ttagcagaaa gagctttatt accagtaata
    18841 ccatctcaag aagaatttcc ttatgctatt agattagttt ctgaagtatt aagttcaaat
    18901 ggttctacat ctcaagcaag tgtatgtggc tcaacattat ctttacttga tgcaggtgta
    18961 cctataaaag atatggttgc aggtatagca atgggactta taaagcatga tggtaaggtt
    19021 gcagtgcttt cagatataca aggtatggaa gaccatttag gcgatatgga ctttaaagta
    19081 gctggaacag agtatggtat aacagcaata caaatggata taaaaattga tggtatagat
    19141 aaagaaattc tacaacgtgc tttaaaacaa gctaaagagg gtagaatcca tatactagga
    19201 gagatgagaa aaactatatc tcagccaaaa ccagaacttt caccatatgc acctaagatt
    19261 gttaaaatgc aaataaatcc tgacaagata aaagatgtaa tagggcctgg tggaaagata
    19321 ataactaaga taatagacga aactggagtt aagatagata ttgaacaaac tggggaagta
    19381 tttatatcag gtattgagat tgatatgatt aagaaagctc aagaacttat aaataatata
    19441 gtagttgaac cagaagtagg aaaaacttat aaaggtaagg taagtagaat aatgaacttt
    19501 ggagcatttg ttgaaatact tccaggaaaa gaaggattac ttcatatatc tcatatagct
    19561 catgaaagag ttgccaaagt tgaagatgta ttgaatatag gggatgaagt tgaagttaaa
    19621 gttacagaga ttgatgaaaa aggaagagtt aatttatcaa gaaaagttct tttaccaaaa
    19681 ccagaacata aaaataaata acttattata taattaaaag caaagtctta ggattttgct
    19741 tttttaaata caaaaaagta gataatttta aaatgatagt tatggatggc ttatagttct
    19801 ttttctgtaa ggctttactc ttataaagaa gctatttaaa agctgattaa tagaaagctt
    19861 tattgatata tatagaatca cttaagttat atttagtgca taaacagagc ttatttttaa
    19921 tagtattaaa taagaaacaa tttgtacata attaggggga gttttaatga taatgatggt
    19981 acttaataag agtaagctca aaaaaatcat aatactaatt ttagtagtgt tattagtatt
    20041 atcaggaggg gtaatggtat taaagttatt taacaacaag ccagtattta atttatttaa
    20101 tggtgtagat ttaccatatg aaagaggtac aaaggataaa agtggatatg ttgcattaac
    20161 ctgtaatata gaccttggat gggaaacaga gtacgtagaa tccattttag aaacacttaa
    20221 aaaagaaaat gtaaagatta catttaatgt aactggaaaa tgggcagaaa agaataagga
    20281 tgaattatta aagataaaaa aacaaggaca tgaaataggt aatcatggat ataaacattt
    20341 agattattct acattatcat atgaagacaa ttatgagcaa atagagacct ctaaaaagat
    20401 aattgaagaa attataggtg aaaaaactaa attttttcaa gcaccagcag gttcctttgg
    20461 tccagaaaca gtaaaggctg ctaaagcatt agggtatact tctatcaaat gggatgccga
    20521 tactatagat tggaaataca aagaccaacc agaggtaatc attgatagaa tgaagaaaaa
    20581 agacattaaa gatagtagta taatcttaat gcatccaacc aacgcaacga caaaatgtat
    20641 agatgatatt atagctattg taagagaaaa aggactaaaa ccagggaaac ttagtgatgt
    20701 atttaagtag acaaagtata aatatttggt taagattgta taagttgtag ttgaattaat
    20761 taaaagactg acttataatg taatacatat aaaaaataaa tataattaaa acatagtgtt
    20821 ttcaataatc caatatgaaa caaagaataa attgttagga gaatgtaatg tataagacaa
    20881 aaatactgga aaatgggctt acaataattg gtgaagaaat accatatcta aagtcaataa
    20941 cattaggtat ttggataaat gcaggctcta ggatagaaga agcacaggtg agtggaactt
    21001 ctcattttat agagcatatg atgtttaaag gaaccaaaaa cagaacatca aaagagattg
    21061 ctagttcaat agataatttg ggtggtcaaa taaatgcatt tacaagtaaa gaatgtacat
    21121 gttattatgt aaaactaata gatgagcata tagatacggg aattgatgta ttgagtgata
    21181 tgatactaaa ttctaaattt gataaaaatg atatagataa ggaaagactt ataatattgg
    21241 aagaacttaa gatgtatgaa gactctccag atgacttatc ttatgattta ttagtggaaa
    21301 atatatatgc taatgatgga ttaggaatga atataattgg gacaaaagaa tctctataca
    21361 atataactag agaatccatg ttagaatact taaataagta ttatattcca aataacgctg
    21421 ttatttctat agctggaaac tttaactttg atgatatggt ggagaaaatc aaatcaaaat
    21481 ttggacactg ggaaaagaaa aatttgagta tagacataag tgaggctaag tttaatcctt
    21541 gctttatatc aaaaaataaa gatactgaac aggtgaactt agctatctgc ctaaaaggta
    21601 ttccttttga aaatgatgaa gaagtctact caatggcagt ggtaaataat attttcggtg
    21661 gaagtataag ctcaaggctt tttcagaaaa taagggaaga aaaaggttta gtatattcaa
    21721 tatactcatc acagacatta tataggaaat gtggtgaatt aggcatattt gcaagtatga
    21781 gtacagaaaa tttacaagat gtatataatt taataaagaa agaaattgaa aatataagag
    21841 aaaactatct tacagaaaaa gaaatatctg aaagcaagga acagttaaaa ggaaattata
    21901 tattggattt agaaagtact agcagtagaa tgatgtctac tggtaaatct atgttactta
    21961 gcaaaaaagt aaaaactaca gatgaaatac ttgaatgtat aaataatgtt aatattaatt
    22021 caataaagaa ggttgttgat aaggtattca atatcgaaaa tattggtaca tgtatagttg
    22081 gaagagatgt agaaaagatt ctacacttgg attaatattg aaaaaagtaa atctctggag
    22141 gtataaaata tgaatttatc tgaaatagca ggtaaggaaa tagttaactt ggtcacagga
    22201 gaaagattgg gggtcattgg agaatgtgac cttatactag atgaaactac aggcggtata
    22261 ttagcgcttc taattccaaa ggaaaaagga ttttttgcca gaagaaaaga taagtcattt
    22321 ttagaagtac catggagaaa tgtaaaaaaa ataggtaatg acatgataat tatagaatat
    22381 gagggatata tttaggagga aaaaatgagt attttagtgc aaaagtttgg tgggacatca
    22441 gtagaatcat atgaaaaaat gaatgaagta tgtaagatag taaaagcata caaaaaaaat
    22501 gatgaagaat tacaattagt attagtagtt tcagcaatgg gaagaaaagg agctccatat
    22561 gctacagata cacttataaa tttgtgtagt gcagtaaatg atgagccaag taaaagagaa
    22621 cttgatttaa taatgtcttg tggagaaata atatcaggaa caattcttgc taatttattg
    22681 aatgcacagg ggatagattc tgttttcttt actggtcagc aagcaggtat aattacaagt
    22741 gatgaatatt ctaatgcaaa gataaagtat ataaatccta aaaaggtaaa aagagcttta
    22801 gatgatggta aggttgtagt tatagctgga ttccagggtg taacagatga tggagaaata
    22861 actactcttg gaagaggagg aagcgataca tcagcagttg ctattggtaa agctttagaa
    22921 tgtgaaacag ttgaaattta cactgatgtg gatggtataa tgactgcaga ccctagagta
    22981 gaaccaaacg ctaaagtatt gagttttata gattatgagg aagtattcca aatggctgac
    23041 aaaggtgcaa aagtaataca tccaagagca gtacagttgg ctaaaagtgg aaatataact
    23101 ttagccataa agaatacaat gaatccaact tttgaaggta caaaaatagg ttctttatgt
    23161 agacacttag aagagaatat agaatatgaa caagaaagag attttaaggt tgctgttgca
    23221 aataaagata gtgtagcaca agttaagatt aaatcagcag aagaagtgtt tacagaagta
    23281 ttaaatgaga tagaaaagaa acttataact atagatatga taaatttctt tatatcagaa
    23341 aaagcatttg ttgtagaaga tgctgatata aaatcattaa aggaaatact agataaattt
    23401 gaattagatt atgaagtaaa tagagactgt gctaaggtaa cattgatatg ttcaagaatt
    23461 gctgatgaaa tgtctggtat catgtcaaag gtagttagag gattatcaaa agcaggggta
    23521 tctcttttac aaacatcaga ctcaaatatg actatatctt gtttagttag tgaagaagat
    23581 atgcatacag cagtacatgc tatacaccaa caattttatt taaaataaac tgtataatac
    23641 aattattttt taatcaaatt taagaatttc atatatatct taatatattt gatttatttg
    23701 gtaaaactaa attaaatata attttgatag gagttttttt atgaaagatt atagagaaga
    23761 taatgaaaga tttgataaag ataattgtag tgaagaatct agttgcgaag agagagaatg
    23821 tataaagcaa tttggtacca atgaaatgcc acctcaacct cctaaagata ttcaatgtat
    23881 aactataatt ggagaaattg agggacattt tataggaaat cctcaaaaaa aagctacaaa
    23941 gtacgagcat ataattccaa tgctatactc aattgaggaa agcaatgatg ttaaaggagt
    24001 gttagttgtt ttaaacactg ttggaggaga tattgaagca ggtttagcta ttgcagaact
    24061 tttaaacagt acatctaaaa aagtagttac tcttgttcta ggaggaagtc atagtatagg
    24121 tgttcctctt gctacagcag gagattactc atttatagca ccaacagcaa ccatgattat
    24181 acatccagtg cgaactactg gtcttgtgat tggtataaat gagacttttg aatattttaa
    24241 aaagatgcaa gatagaataa ttcaatttat aataagaaca tcaaatatca aaaaagatgt
    24301 acttgaaaaa cttatgcatg aaaaagatga acttgtaagt gatgttggta gtgtattaat
    24361 aggaaaagaa gctgtggatt atggtcttat agatgaagtt ggaggactaa aagaagcact
    24421 taaaaaatta agagagctta taaaagaatc tgaggaagaa aaaaataatg attaaaattt
    24481 gtttaaataa taaaatttat gatataatga tgtaataaag taggagtgtt agtgttaagg
    24541 cattagcact ttttgctgtg aaggggtaaa acttgctaaa aataaggagt gatattaatg
    24601 gccacgaaaa agaagaaaaa aaagaaggta aataccttaa gttttaatgc agaatatcat
    24661 aatttaataa caatatttat aggtgtattt ttattatata gtttaaattc taattctatg
    24721 ggatggatac ctgtgttaat gcaaaatctt tttaagggac tatttggagg gctttcaata
    24781 gcaataccat ttatagtaat tataacagga cttttaggat tttttgatgg aaatgaatat
    24841 atatataggc taagaaagac taaactatac tacataatta ttttatttat atttgtattt
    24901 tatggattat taaatgcagg aactcttcct gtagatagcc cactaaaagg taacatgttt
    24961 gatgatgtta tgaaattggg tgtaagtgga caaggtagtg gtttgatagc aacaactatt
    25021 gcgtattata tgagtaaaat atttggtata gcaggtggat ggttaataag tatcttcgca
    25081 cttatacttt ctgtaatgtt tatatttaat atttctataa aagatttggt gtcaaatgca
    25141 aaatcaaaat ctaaagcatc taaagacagc aatttaacgt ttaaagataa aattgcaaat
    25201 atgaaaaaat ctgcaataga tatgatgact gatgaagtag atgatactac tataaataaa
    25261 aaaccaggtt tctttaaagg gttaatgtca aaaggtctta ataatgatga tgaagaagat
    25321 gaatattttg aagaagaaaa tagtgatggt gtagatgata aaactataaa aatagttgga
    25381 tttaataagg cagaagatga gtatttagaa atattagaag gaactcaaag tatgccagag
    25441 ttagatgttt taaaagaatt acaaaaagct accaatgaaa atccagttgt agatactaaa
    25501 ccagaaaaaa aagttgatat agctaaatct aatttaaata tagaaaaaac tcaacctatg
    25561 agtattgtag cagagccagt taatgaggat tattcaaact ataaaaagcc tagcattgag
    25621 cttttaaata aagtaaataa gaagtctgat gaaaatggta aaaagaaagt gttgaaaaat
    25681 gcttctcttt tagaaaagac actatcagat tttggagtgg aagcaaaaat taatcaagtt
    25741 acagttggac ctactataac aagatatgaa atacaaccaa gtccaggagt caaggtaagt
    25801 aaaattgtaa atttaactga tgatatagct ttaagtttag cagctaaaag tataagaatt
    25861 gaagccccaa ttcctggtaa aagtgcaatt ggaatagaag ttccaaatga agaagctcaa
    25921 atggttggtg tgagagaagt tctagaaagt gaagaattta ataattttaa ctctcctctt
    25981 gcaatgggac ttggaaaaga cgtagcagga aaaattataa ttggagatat aggtaagatg
    26041 ccacacttac taatagctgg ttctacaggt tcaggaaaga gtgtgtgtgt aaatacatta
    26101 ataagtagta ttttatataa ggcaaatcct gatgaagtaa aattactatt aatagaccca
    26161 aaagtagttg aacttgcaaa ttataatgga ataccacatc tattgatacc agtagttact
    26221 gaccctaaaa aagctgcaaa tgctttaaat tgggcagtta cagagatgaa tagaaggtat
    26281 aaattatttg cagatgctca agtaaaagat gtaacaagtt ataatgagaa agcggaagaa
    26341 aaacttccta aaatagtaat aataatagat gagttagcag atttaatgat ggcaagtgca
    26401 aatgatgtag aagattatat ttgtagatta gctcaaatgg caagagctgc tggaatgcac
    26461 ttgattgtag caactcaaag accatctgtt gacgttataa caggggtaat aaaggctaat
    26521 ataccatcta gaatagcatt tgcagtatca tctcaaactg attcaagaac aatccttgat
    26581 atgggtggtg cagagaagct tctaggtaaa ggtgatatgt tattctatcc acttggtgca
    26641 gcaaaaccag ttagacttca aggggcattc atatcagaga gtgagtcgga aaaagtaatt
    26701 gattttgtaa aaagtcaggt taaagatgga ataaaatatg aagaagatat aattgaaact
    26761 atatctaagg ttaatacttc aaagagtagt gatgaggatg agtttttgag tgaagcgata
    26821 gaatttgtcg tggaaagtgg tcaagcatct gcctctatgc tacagagaag atttaaaata
    26881 ggattcaata gagcagctag acttatagat tctatggaag aaagaggcat aattggagca
    26941 agtgagggaa gtaaacctag aaaggtatta ataagcaaac aggatttgca gaatttagaa
    27001 ggtgaataga attgtcagtt ataaaaatag aaaaagcact taagctagat aaagtaatat
    27061 ttgtagatgt gagaactgaa ggagaatatg aagaagacca tatattgaat gcaatcaata
    27121 tgcctctttt taaaaataat gaacataatg aagttggaac aatttataag atgcagggaa
    27181 aacatgaagc aatacaaaaa gggtttgact atgtatcgta taaattaaag gatatatatt
    27241 tacaagcagc agaacttgca ttaaattatg ataatattgt catatattgt gcaagaggcg
    27301 gaatgagaag tggaagtata gtaaatttat tatcatcatt aggtgtaaat gtatatcaac
    27361 ttgaaggtgg atataaggct tatagaaatt ttgtattaga gtatctaagg catgtaatgg
    27421 atacaaaaaa ctttgtatct gttcatggat tgactggtac aggaaagact gatttgttac
    27481 atttattaga tgaaaaagga atagatgtac tggatttaga aggcatagct aaaaacagtg
    27541 gttctacctt tggttttata acttttgata aaaagccacc atctcaaaag aactttgaaa
    27601 caaaactatt tgaaagtgta tttttttcga aagagaatta tatatttgtc gagagtgaaa
    27661 gcaaacgagt tggaagtgtt acagttccaa atgaaatttt cgaggcaatg acacgagaag
    27721 gacatcatat attattagaa tgtgatattg aaaatagagt tgatagactt tgtagagatt
    27781 atatttatga taaagatgaa ggtaatatat tgattttaaa agaatgtata aacaagttta
    27841 gaaaaagatt gggtaataaa gtagtagatg attatattga tttattagaa tcaggtgaat
    27901 ataaagaact tgtaaaaaga tatcttttag aatactacga cccactttat atgcattcag
    27961 tagagaaata taagtatagt aagattataa attttaatga tacacaaaaa gctttagaag
    28021 atgttataga cttatatgag agtatattgg aaggagaaag tgaatgttaa aaatagcatt
    28081 ggaatcatta ggatgctcaa aaaatttagt agatgcagaa ataatgatgg gaattttaaa
    28141 taacaaaggc tataaattaa ttggagattt tgaagaagct gatgtaatta tagtaaatac
    28201 atgtgggttt atagagtcag ctaaacaaga atctatagat acgataataa acttttcaga
    28261 gttaaaaaaa actggcaatt taaagttgtt gatagtaaca gggtgtctag cccaaagata
    28321 ttctgaagaa ttaaaaactg aaattcctga aatagatgct atagtaggaa caggaagcta
    28381 tcaaaatata gataaaatac ttaaagaatt aagtgaaatg catcaaattg taagccttaa
    28441 tgatatagag tttgtattta atgaagattt accaagatat atatctacac ctagctatat
    28501 ggcctattta aaaattggag aaggatgctc caataattgt acttattgta taataccaaa
    28561 actaagaggt aaatatagaa gtagaaaatt tgaagatata attaaagaag ctaagaaatt
    28621 agctgaatct ggagtaaaag aacttgtggt tatagcacaa gatacgacaa agtatggttt
    28681 tgatttatat ggaaaagaaa gattatcaga acttttagaa gaacttgcaa aaatagatgg
    28741 atttaagtgg ataagggtta tgtattcata tccagaatct ataacagagg aattgataca
    28801 agttataaag aaatatgata atatatgtag ttactttgat atgccaatac agcatgcaag
    28861 taacaatatt ttaaaattaa tgaatagaaa aactactaaa gaagatatat taaataaaat
    28921 caatctgata agaagtaata taccagatgc tatacttaga actacgataa tagtagggtt
    28981 tcctggtgaa acagaagatg acttcaaaca acttgtggac tttgttgaag aggttaaatt
    29041 tgatagactt ggtgcatttg catattcaag agaagaagat acaccagcag atagattgcc
    29101 aaaccatata gatgaagaag taaaaataca aagaagagat actttaatga tgattcaaca
    29161 aaaaatatct gaagaactta atgacaaaaa gataggaaaa acttatgagg tgttaataga
    29221 agaacagata gaagataatg tatatacagg aagaacacaa ggtgatgcgg aagaaattga
    29281 cagtatagtg tatgtaaaaa gtgtagacaa tcttgaagta ggagaatttg taagtgttca
    29341 aataaatgat gcaatggaat acgatttaat gggagatgtt ttatatgaac ttgcctaaca
    29401 agttaacttt gtttagaata tttttaatac cagtatttgt tttaattatg ttgctcaatg
    29461 taccaaataa atttttaata gcttgtatta tttttataat agcttcaatt actgatgctt
    29521 tagatggaaa aatagctaga aaatacaatc tagtcactga ctttggaaaa tttatggacc
    29581 cattagcaga taagttattg gttatttcag cacttacatg tatgatagaa gaccatcttg
    29641 taagtagttg gatggtaatt ataatagtgg ctagagagct tacagttagc atattaagag
    29701 ctatagctgc tgctgatgga aaagtaattg ctgctggaaa cagtggaaaa cttaaaacga
    29761 taactcaaat ggtatctata gtgtttttat tgttaggcgc tcagtttgaa aatgtattga
    29821 tattaaatat tggtgaaatt ctcattctta tagctacact acttacatta tattctggat
    29881 gggaatatct atataaaaat aaagagcttt ttatgtcttc taagtaaaaa attatgcttt
    29941 aataaataaa aactaatgat taataaataa aaaataacaa cttaaaattt taaaaatgta
    30001 aaaaagggta tactattata gtatacctct tttcatttta agaatatttt cttttgtgta
    30061 tataattatt aataatggtt tataaataaa atgtaatgaa taaaaatata atcattagta
    30121 gcgtttttaa attgactagg tttgatttat gttatataat taatatataa caagagaaca
    30181 aatgtttgta gataaatgaa gggatggtat agagatgagt gtagatcaag aaaaattaaa
    30241 agcgttgaat gaagctttag gtaaaattga aaaagatttt ggtaaaggtt cagtaatgaa
    30301 attgggagaa gcaacatcta tgtctataga tgttatatca acaggagcga ttggtttaga
    30361 catagctatt ggtataggag gtctacctag agggagaata gttgaagtat atggtccaga
    30421 atcttctggt aagactactg ttgcgcttag ttgtgtagca tcagctcaaa aagatggagg
    30481 aatagctgca tttatagatg cagaacatgc acttgaccca gtatatgcaa aagctttggg
    30541 tgtggatgtt gataacctaa taatatctca accagataca ggtgaacagg ctttagagat
    30601 agcagaggca ttgataagaa gtggagcgat agatataata gtaatagact cagtagcagc
    30661 attagttcca aaggctgaaa tagatggaga tatgggtgat tctcatgtag gtttacaagc
    30721 tagacttatg tcacaagcac ttagaaagtt aactggttca attaaaaaat caaattgtgt
    30781 tgctatattt ataaaccagt taagagagaa agtaggaata atgtttggaa acccagaaac
    30841 tactactgga ggacgtgcac taaaattcta ttcatcagtt agattggatg ttagaaaaat
    30901 agatacaata aaacaaggtg ataaagttat aggtagtaga actagagtta aagttgttaa
    30961 aaacaaagta gcaccaccat ttaagcaagc tgaatttgat ataatgtatg gagaagggat
    31021 ttcaaaaatt ggagaccttt tagatatagc tgctgatgta gatatagtta aaaaatcagg
    31081 ttcatggtat agttacaatg atactaaact tggacaagga agagaaaatg ttaaaaaatt
    31141 cttggaagat aatttagatt taactactga aatagatgag aaagttagag cattttacaa
    31201 tttaaatgaa gaacatgaag aatcaggtac ttcagtatca aaagaaattg tagaagaata
    31261 agtaaaaata caaaaaaata actagtaatt aaagacatgc cacgctccct attagcttga
    31321 cacaatgttg aaaaaattat aaaattaagt gaggataaaa tatctaaatt taattttaat
    31381 tattaggaat attttttaat catagtgatg acattttggg attattaacg aaggaggtgg
    31441 atgtcataga tagtgtagta atgattgtaa taggtgcagc tgttggtatt atagctggat
    31501 attttgttag aaaaaatata tctgaagcaa aaattggaca agctgaaaac ttggccaaag
    31561 aaataataga taaagcacac cacgactcag aaacagtaca aaaagaaaaa ttactagaag
    31621 ctaaagaaga gatccataag tggagaacag aagctgaaag agaaaacaga gaaagaagaa
    31681 cagaagtaca aaagtatgaa aaaagagtag tacaaaaaga agaagtctta gatagaaaat
    31741 tacaaaattt agaatctaaa gaagtaaacc taagtgaaaa attaaaggta gtggaaaaga
    31801 aagaagaaga agtcgaagta ataaaaactc aacagttaga aaaattagaa agtatatcag
    31861 gaattacttc tgataaggcc aaagaaatca tcttaaccaa tgcggagaga gatgtaagac
    31921 gtgaaatgtc tataatgata aaagagatag aaagtcaagc taaagaagaa gctgataaga
    31981 aatcaagaga aattatagga tatgcaattc aaaaatgtgc agcagatcac gtagccgaaa
    32041 ctactgtaac agtagtaagc ttgcctaatg atgaaatgaa aggtagaata ataggtaggg
    32101 aaggtagaaa tataaggact ttagaaacct taacaggtat agaccttata atagatgaca
    32161 ctccagaagc cgtaatttta tcaggatttg atccaataag aagagaaatt gcaagaattg
    32221 ctctagaaaa attaatagca gatggaagaa tacatccagc tagaattgaa gaaatggttg
    32281 aaaaggcgag aaaagaagtt gacaatatta taaaagaata tggtgaacaa gctgcatttg
    32341 aaactagtgt acatgggatt catccggaat taataagatt attaggtaga cttaactata
    32401 gaactagtta tggacaaaat gtacttaaac attctataga agttgctcat atagctggta
    32461 taatggctgc tgaaatagga gcagatatta gattggctaa gagggcaggt ttattacatg
    32521 atataggtaa ggctgtagac catgaaatgg aaggtacaca tgttgaaata ggtatggatt
    32581 tacttagacg ttataaagag tctaaagaag ttatacatgc catgagtact catcatggag
    32641 attacgaacc tcaaacagta gaggctgtat tagttacagc agcagatgca atatcagctg
    32701 ctagacctgg tgcgagaaga gaaactttag aagcatatat aaagagactt gaaaaattag
    32761 aagaaatagc taattcatat gaaggtgtag aaaaatcatt tgctatacaa gctggtagag
    32821 aaataagaat aatggtaaaa ccagaagcta taaatgatga agaaatacat ctattggcta
    32881 gagatatgac taagaaaata gaggatgaac ttgaatatcc tggacaaata aaagtaagca
    32941 taataagaga aacaagagct atagagtatg cgaagtaaaa gaaataatat ctaaataata
    33001 agaaaatatt tttagaaatt taaatttgcc acaagatatg ataatatatc ttgtggcttt
    33061 taaattgttt aagtttaatt ttatataatg caaaaataat ctaagtgcta aaagtgctac
    33121 ttacaaaaga ttaataaaat aaagctttat atatgtatta tttatataat tatccaagtt
    33181 tgtttgatat aatgaagttg taaaatcaat actttactac aaaataaata gtaaatacta
    33241 cagtaaaatc ta
//
LOCUS       DAMJYN010000038        33165 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.039, whole genome shotgun sequence.
ACCESSION   DAMJYN010000038 DAMJYN010000000
VERSION     DAMJYN010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 33165)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33165)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33165
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.039"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(164..2830)
                     /locus_tag="PC466_001979"
     CDS             complement(164..2830)
                     /locus_tag="PC466_001979"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HDF2769363.1"
                     /translation="MENTNLSKTYNPKDFEARLYKKWMDEGYFKSKPNPDKKPFTIMM
                     PPPNITGQLHMGHALDHTLQDILIRWKRMDGYEAFWLPGTDHASIATEVKVVERIKKQ
                     EGKTKYEIGREEFLKRAWEWKDEFGGKISNQLKQLGDSCDWDKERFTMDEGCNEAVIE
                     FFVSLYEKGHIYRGNRIINWCPDCKTTLSDAEVEHEEHDGNFYHIKYPLKDSEDFLEI
                     ATTRPETMIGDTGIAVNPEDDRYKHLIGKTAILPLVGRELPIVADSYVDLEFGTGAVK
                     MTPAHDPNDFEVGLRHNLEQLNTMNEDGTMNEVCGKYEGMDRFECRKAIVADLKEQGY
                     LIKIKAHNHNVGTCYRCHTVVEPRLSEQWFVKMEELAKPAIDILKKGELEFVPDKFDK
                     TYLQWLENIRDWCISRQLWWGHQIPAYYCQECGEIVVARKMPDKCPKCGSTHFKQDED
                     ALDTWFSSALWPFSTLGWPNKTEALDYYYPTSVLVTGYDIIFFWVVRMAFAGMFCMNE
                     KPFDHVLVHGLVRDSQGRKMSKSLGNGIDPLEIIEQYGADALRFTLTTGNSPGNDMRF
                     YMERVEFARNFANKLWNASRFVFMNIDEDIIKNMTRESVKEDLTLADKWIISRANNIV
                     KEATNNMDKFDLGIALQKIYDFTWSEYCDWYIEMVKPRLYGEDANAKSAALYTLTYVL
                     EKILKLLHPYMPFITEEIYTHLPTVEGCIIVSEWPKYNEEDNMAEEEDMMNLLMEGIR
                     SIRNVRAEMNVPPSKKAKLIIIPSEEKIEAIELGKDYFITLASASNVEIAKDKSNVPE
                     DAVGVVIDGVEIFIPLNELVDFEKEIERLSKEKKKLEGEIKRVNGKLANQGFLAKAPE
                     SLIEEEKVKKEKFEEMIKSVEERLTNLESKIK"
     misc_binding    complement(2906..3168)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(3469..4296)
                     /locus_tag="PC466_001980"
     CDS             complement(3469..4296)
                     /locus_tag="PC466_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HDF2769364.1"
                     /translation="MKIKDNKAVFHVFIRIFLIAVLILTGTLLEEKINNVPVENISSK
                     GENTLELLSQSNTLGEIIYKASQEETKGPGATSEKVAYITIDDGPSKYTNALLDILKE
                     NDVKATFFMLNQNMKNHKEEVRRVLEEENSIGFHSVSHDIHKLYKSPEVTVGEFNTCN
                     NTLQEITGQSSKLIRLPYGSKPYMPEGSYNKLMANDYLIWDWNLDTQDWKSSTSQIVS
                     NILYYGRKRDELVVLIHEKEQSLNALNNIIRILKERGYTILPITENITPKNFWQENL"
     gene            complement(4344..5780)
                     /locus_tag="PC466_001981"
     CDS             complement(4344..5780)
                     /locus_tag="PC466_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron hydrogenase"
                     /protein_id="HDF2769365.1"
                     /translation="MNTRNDNSKILEIYKMKLFGELVKAVWNDDIEDIENLPNKILNE
                     DLKDNLNNYFSGKFDKDTMVNLIRVTMGLDVTEDTDKNLKESLHEAVNLDEVKRPIIS
                     VISDACKYCDENNKEDESCKIRSKHINCNEEDVCSACGDCVSRCKLGAISDKIEFIPM
                     IKLLKDIKSPVYAIVAPAFVGQFGKDVSPGKLRTALKKIGFEDMIEVALAADMLTAKE
                     AYDYYEHMKKDEEGCFITSCCCPIWVSLIQNSFPQILENVSPSVSPMIACGRAVKILN
                     PDAKVVFIGPCMAKKKEAMLEDIKDAVDFVLTFKELQEIFDALELNPAIMDESNRVEA
                     SLSGRVYARTGGVSKAVKLSVRRIDKNIKFEEKAFEGTKECMDGLKKVLNKEIEATFI
                     EGMGCVGGCVGGPKRILSVEEGTKNVDEYSESTNMETPFDNLNVLQFLTSLGIKRVES
                     LGEKEEEKVKKIFSRDIKSNKKENKYKK"
     gene            complement(5867..6736)
                     /locus_tag="PC466_001982"
     CDS             complement(5867..6736)
                     /locus_tag="PC466_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HDF2769366.1"
                     /translation="MKLQKMGMRTIKTGISVTLCMILGNYLVENMFYSLVACIISVQD
                     TVKGSLKTGINRVEGTILGGIIGFIFAIIKAGDPFLCGLGVMCSIYLCNLFKIKSVVV
                     ACVTFLAIHLGVGNSDPVYYSLHRVLDTSVGVLFGVLVNYYVARPNYLNSVIDEFKKI
                     EELSMLLIEDKILRKENLNVEKFEEEVEKLEEIYSKLIDELDYSLSETNIEKIENALR
                     ICREIHFHMQSIELLENKLYLKEHTYKYLKKTYNVDKLDWNIDEEKSPVFNYHLMKIM
                     IEIELLRKLNKSY"
     gene            complement(6894..7547)
                     /gene="phoU"
                     /locus_tag="PC466_001983"
     CDS             complement(6894..7547)
                     /gene="phoU"
                     /locus_tag="PC466_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HDF2769367.1"
                     /translation="MVNNSLDISIDTLKEQTVLMMEKCEEAIEKSVTCMIEKDLEGAR
                     KVVEDDEEINKLREEIRDKSIELIVLKQPMARDLRFIYSLGNISIELERIGDYAANIA
                     REMLKIGGEAYIKELIDIPKMAKECKSMMSQTREALILFDASIAYDVGTKDDIVDGLY
                     EQVQIDCLKIMHENSNTIDQGVKLLLIGRYLERIGDHITNVCEKIIFAIEGKMVEIG"
     gene            complement(7575..8339)
                     /gene="pstB"
                     /locus_tag="PC466_001984"
     CDS             complement(7575..8339)
                     /gene="pstB"
                     /locus_tag="PC466_001984"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HDF2769368.1"
                     /translation="MELIDKIKMSVKDLDLFYGDKQALKKINMDIKENKVTALIGPSG
                     CGKSTFIRTLNRMNDLIEDVTIKGNISVDGEDIYTSDDVINLRTKVGMVFQKPNPFPM
                     SIYDNVAYGPRTHGLRDKKQLDKIVEESLKGAAIWDEVKDRLKSSALGLSGGQQQRIC
                     IARAIAMRPEVILMDEPTSALDPISTLKVEELIEDLKKDYTIVIVTHNMQQAARISDE
                     TAFFLNGEVIEFSDTKTMFTTPVDKRTEDYITGRFG"
     gene            complement(8358..9182)
                     /gene="pstA"
                     /locus_tag="PC466_001985"
     CDS             complement(8358..9182)
                     /gene="pstA"
                     /locus_tag="PC466_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003460575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HDF2769369.1"
                     /translation="MRKFKENLLKSLVYLSALFTIVSLVIIVGFIFIKGIGNMNFNFL
                     FSNYSASGDGGILPMIITTLYTVVVSIVVATPIGILAAIYLQEYAKKGKAVTAIRFAT
                     ESLSGIPSIVYGLFGGIFFVVTLKMGYSIVAGSLTVAIIILPVIIRTTEEALKTVPQA
                     YRESSLALGATKFQTLYKVVLPSAIPGILSGVILSVGRIIGESAAILLTAGTVAKMPG
                     GIFDSARTLTVHSYLLTKESGDIATAASIGIVLIVIVLALNMLARFVAKKLNKANY"
     gene            complement(9184..10101)
                     /gene="pstC"
                     /locus_tag="PC466_001986"
     CDS             complement(9184..10101)
                     /gene="pstC"
                     /locus_tag="PC466_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HDF2769370.1"
                     /translation="MIVKSRLVGLEKNDNNGNKTKYVIEKVAKNIFLLSALVAVASLL
                     LIIGFVFYKGLRPFIFEGYSFIDFLTGADWVPSANKFGISSMIVASIFATLGALVIGV
                     PVGILTSVFIAEVAPKRLAKIMSPAVELLAGIPSVLYGVFGLAVIVPTIQSIFNLPKG
                     QSLLAIVIVLAVMMLPTIISVSETAIRAVPKAYKEGSLALGASKIETIFKVVLPAAKS
                     GVLAAVVLGVGRALGETMAVILVAGNSPVMPTAITDSVRPLTTNIALEMGYAFGTHQE
                     MLFATGVVLFTFILILNLVLNKLSNKAVN"
     gene            complement(10483..11718)
                     /locus_tag="PC466_001987"
     CDS             complement(10483..11718)
                     /locus_tag="PC466_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2769371.1"
                     /translation="MRIFYLEIKRVLHSRRTLILLLLALVLSALMAFLPITYEGINYL
                     DNNGKVVELSGLDAIKYKKTIYANNSEISSGVVTPKKLKHALNIWKKTEEKYGKVGSE
                     DFPLDIYSKSILPIRPLLNRLPEAFANSETGFATELSEINTNDLDSFYEQCKTHLNDI
                     MKIERQTSSAQMKAQELYRKVDTPFEIYPGYSKDAFDYIIFYIFILLIICVAITAPTF
                     SGEYQTQSDSILRCTKHGHTRLAFTKILALFSIFIVMFVVCISIHLAISDLAFGTECL
                     KTSFQMLFSVISLVNINLLQAQILIAIGGLISILAMVSLTLFLSAKCKDSLTSMLIAF
                     SICLIPMGIGVSWIGYLLPPGGIGLKISLLYQMTSFNFLHLGGMSFWTPHIILFFSVI
                     EIPIFIFLAIRTYCKHQVS"
     gene            complement(11719..12606)
                     /locus_tag="PC466_001988"
     CDS             complement(11719..12606)
                     /locus_tag="PC466_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2769372.1"
                     /translation="MELKIEHVTKKFKDKIAVEDVCLTLTPGVWGFLGANGAGKTTLM
                     RIITDIMKPTNGKILYNGKNIYIMGAEYRNLLGFLPQEFGFPQDFSVKDYLEYIAALK
                     DVPPREVKGKINNLLEILTLSDVKNKKIIKLSGGMKRRVGIAQAMLNDPKILIMDEPT
                     AGLDPGERVRFRNFISEFSHNRVVLISTHIVSDIEYISTQNAIMKSGKILDVGTTDKL
                     VKKVEGKVWECLISNRDISKYEMNLRIINQRSEKNNQVSIRYLAEKSQIDNSIAVEPR
                     LEDLYLWLFPEAVYSKEGK"
     gene            complement(12751..13866)
                     /locus_tag="PC466_001989"
     CDS             complement(12751..13866)
                     /locus_tag="PC466_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2769373.1"
                     /translation="MKKINNFTYRKLRDKYKFIKREKNTEAYLKYKLYIMLAIYTGIV
                     LVLMFMADYTFSNFSNPLVKWLKLRRDVLFFLVFIIGYITIFNFYWKKPWNYLREIIN
                     ATHTIYQQNDELVELSKPLKEIEQQMNQIKMSVLLSQQAVKEAENKKNNLVMYLAHDI
                     RTPLTSVIGYLSLLKEIPNMDNSQKSKYTEVALDKAQYLEKLINELFEITRYNSNQIK
                     INFEKVDLYYMLLQLKDEFYPLLSEKGNRAILKANESLTIKADSEKLARVFNNILKNA
                     IAYSYPNTEIIISAVHKDSKVDIAFRNYGQTIPEEQLSAIFEKFNRLDEARKSDMGGA
                     GLGLSIAKEIINLHGGDITVQSKDEVTTFTISLPTSI"
     gene            complement(13902..14600)
                     /gene="vanR"
                     /locus_tag="PC466_001990"
     CDS             complement(13902..14600)
                     /gene="vanR"
                     /locus_tag="PC466_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002594737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanR-ABDEGLN family response regulator
                     transcription factor"
                     /protein_id="HDF2769374.1"
                     /translation="MSGKILVVDDERDIADLIEVYLTNENYIVYKFYSGLDALNCINL
                     NEFDLAILDVMLPGVNGFSLCQKIREKYTYPIIMLTAKDEETDKITGLTLGADDYVTK
                     PFRPLELVARVKAQIRRYKKYSGSLQSGEELSHIFSFLGLELNTQTYECHLNGKALSL
                     TPTEFSILHVLLKNKGSVVNSENLFHAIWKDEYYNKSNNTITVHIRHLREKLGDTVDE
                     AKYIKTIWGVGYKI"
     gene            complement(14982..15662)
                     /locus_tag="PC466_001991"
     CDS             complement(14982..15662)
                     /locus_tag="PC466_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2769375.1"
                     /translation="MQTKILIIDGDKDNCQKLKGFLEEKEISIDLAYNCEEAIGKIFS
                     NKYDLIFLEIILTDGDGWTLCKKIRNVTTCPIVYMTYINEEQSILNALNSGGDDYLIK
                     PLNLEILYAKVKAILRRMNSYVNNNENNTKLEEYNRTSGVIKLEDKIIKLTPTENKLL
                     NFFIENPEKTLTTKEIYEHVWMNEYLEDNYSVVVAVNGLRKKIEKDYKNPQKIITIRG
                     AGYYFNKE"
     gene            complement(15712..17727)
                     /locus_tag="PC466_001992"
     CDS             complement(15712..17727)
                     /locus_tag="PC466_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HDF2769376.1"
                     /translation="MKKYNILKGTLIVLIVSLLAIAGLNLLYKYDNKYTYKSIRASNG
                     ILTIDNDTFTKGKLVFLIDDWEFYNHKIFKPNDFTEQDIKPEYVFIGQYPDFSMRKGN
                     QSPYGNATYRMRIKNEGEDKLLSLELPEIFSASEVWINGEIVSKLGDVGTEKYRPKIK
                     NSVVSFIAKKDTEIIINVSNFSHYYSGLYYPPALGETKDISNMMFYRLLFYSIICFTT
                     FAIAIFSLSVWFLSNKSKLYLYFGCMCVFFAIHVSYPFVHLLGLPLVSFTYAVEDSSY
                     FMVVLCIICINGSISKIEEDKVYRFLILPLGITMSIISIVIPIILLPYDMYFVNIYGK
                     LIDIYKYIVFIYILMSSLVSIYKKTCSEHISSYILVSVNTVFGISILFDAVTSNRFEP
                     IFTGWQTEYCGFIIVILFSLMMINRNRIIIKENEKLTRNLEHEVEVRTNELTTLLNER
                     KKFLADVAHDLKAPVSAIQSFIDLIKVGNIHVDEETRTYLYAINQKSNEVQNRVRSLQ
                     EFTSQDKSIGISEKICLNDFIKEIYENNLPDTQACGVNFETYILEKKIYAKINKEMLT
                     RAFENLIYNALTFTPFDGKIILSMDKEDGFAIIKVSDNGKGIPPENIPKVFDRFFTER
                     DNNEPKGQGLGLYIVKSIIREHGGEIFVDSELGKGTVFTIKLSLCFL"
     gene            complement(17799..18476)
                     /locus_tag="PC466_001993"
     CDS             complement(17799..18476)
                     /locus_tag="PC466_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2769377.1"
                     /translation="MYNLLVVDDDVDILNINQIYFSNIGFNVYTSETAKDAMDIVERI
                     VLDCIILDISLPDIDGYKMCNDIKEKVNIPIIFLSNYEHEEEKVRGFLAGGDDYITKP
                     YSLKELELRIYARMRQYKNITSVPNVLKFSALVINVNSRKVTFDGESIDLTTMEFEIL
                     LFLAENKEQVFSKIEIYNQVWKMPDIGDQHTVQVHIAQMRKKINSLSREHQYIQTVWG
                     KGYKFVP"
     regulatory      complement(19056..19139)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            complement(19372..20214)
                     /locus_tag="PC466_001994"
     CDS             complement(19372..20214)
                     /locus_tag="PC466_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein"
                     /protein_id="HDF2769378.1"
                     /translation="MFKKKIGVLLASTMLVGALAVGCSSNSGGSGDSGDSSKVSVSGS
                     TSIGPLMETIGEKFQEKNQGVSVEVQQIGSSGGIKNAIEGTSEIGMSSRDLKDEEKSA
                     GLKETKIAIDGIALITNTANSVKNLTMDQVKGIYTGKITNWKEVGGNDAPIVIVSREE
                     GSGTRDGFQEIVGFDSEELTKDAQISDGSGNIKTTVEGNENAIGYISFGYVDEKVNSL
                     KINDVEATDANVMANKYPISRPFILVNKEDGLSEKGKALIDYILSDEGQALVSEKGFI
                     KVNQ"
     gene            complement(20466..22250)
                     /gene="pepF"
                     /locus_tag="PC466_001995"
     CDS             complement(20466..22250)
                     /gene="pepF"
                     /locus_tag="PC466_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HDF2769379.1"
                     /translation="MGTDRSTIEEKYKWKIDKMYSSKEEIEKDISKVKNLIQEVKEYK
                     GKLSESKENLYKVLNISENASRIVQNLYVYTHMKQHEDTRINDNQGRATKTEMLSTDL
                     GVATSYIVPEILAIEENKLSEYLKDEKLSFYTKYIKDILRDKPHTLSEREEEILAATS
                     ELSTIPENVYDMLAYADMEFPEIEDEEGNKVKLSHSNYSLFIKSKNSRVRKDAFEGEF
                     STYEKYKNTFASTLYGGIKSEIFYAKTRKYNSAIEASLFSDDVSLDVYNNLISAIDKS
                     IPNLNKYVELKKKFLGLNEIHMYDLYVPLTDKFDMDIPYDKAQDIILEALKPLGEKYL
                     KVIKSAFDEGWIDVYDNEGKKGGAYSWGSYDSHPYILMSYKNDLNSLFTLIHELGHSV
                     HSHYSRTSQPFLYSDYKIFVAEVASTLNELLLINYLLENSKSKDETIYLLNYYLEQFR
                     TTVHRQTMFAEFEKIVHQRVESGEPLTADEFTNIYYKLNEKYYGKSAIVDKQIGIEWA
                     RIPHFYSNFYVYKYATGFSAASALSQQILSEGSTAVDRYINFLKSGGSEYPLEQLKSA
                     GVDMTKKESIEEALNVFAELVNKLEKEL"
     gene            complement(22316..22981)
                     /locus_tag="PC466_001996"
     CDS             complement(22316..22981)
                     /locus_tag="PC466_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HDF2769380.1"
                     /translation="MIDIGSKEIAIRLLLALIIGGIIGLEREKIRQFAGFRTHILIAI
                     GSCIVSITSIQLFFDYNLYTNADPARMPAQVLSGIGFLGAGAILKNKGGVKGLTTAAG
                     MWATACIGIAVGYGYYELAILGGLFVMIALFVLRIINTFLFSQEKNVLILKLSNLDSI
                     PFLYDKFEKNQLIVRNMEIECRNEEYWKVNFFVSYAKRIHLHDVMKEINMIEGVINVD
                     YLD"
     gene            complement(23132..23293)
                     /locus_tag="PC466_001997"
     CDS             complement(23132..23293)
                     /locus_tag="PC466_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartyl-phosphate phosphatase Spo0E family
                     protein"
                     /protein_id="HDF2769381.1"
                     /translation="MANNELEALKNEIEAVREEINTYIEYPEIFQEELVESSKKIDIL
                     INKYMYLSK"
     gene            complement(23371..23880)
                     /locus_tag="PC466_001998"
     CDS             complement(23371..23880)
                     /locus_tag="PC466_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HDF2769382.1"
                     /translation="MKTRKMTFLGLMIGYSLALYVLETYIPNPLIVIFPGAKLGLSNI
                     ITLISLMLLGVKDTVIIVTIRVILSSIFAGPLSYLLFSIGGAYLSLLFMYLASKIKDL
                     SLIGISIIGAIGHNIGQLIVASLIIENILAIGYLPFMLMASLVTGMFVGLVSRYTIPK
                     LKHFYSKFY"
     gene            24086..24304
                     /locus_tag="PC466_001999"
     CDS             24086..24304
                     /locus_tag="PC466_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HDF2769383.1"
                     /translation="MTVYDLKIGEKGFINSIDGDIKLSKRLLALGCINSTEIEVKKVA
                     PLGDPIIIRFRGFDLAIRKSDAKNISLQ"
     gene            24322..26268
                     /gene="feoB"
                     /locus_tag="PC466_002000"
     CDS             24322..26268
                     /gene="feoB"
                     /locus_tag="PC466_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HDF2769384.1"
                     /translation="MINVALLGNPNVGKTTVFNLLTGSNQYVGNWPGVTIEKKEGFLG
                     KEIKVVDLPGIYAMDTFSNEEKVSKSYLENEDVDVIVNVVDASNLSRNLYLTTQLMQF
                     NKPIVILLNMLDIAESKGVNIDAKKLSEELGVIVVPIIAKKKNGVDRIEEEIKGATQK
                     AFIYQKNFGSETETYKKLESILSRCTKTTYTQKKSISDKIDNIVLNPILAYPIFIGVL
                     FLLFKFTFDWVGGPLQEGFASLIEAYISAPVSDMLSNSSPWFKSLIVDGIIGGVGGTL
                     PFFPLIFTLFFGISLFEDSGYMSRTAFLMDKVMRKVGLSGKAFIPIVMGMGCSSPAIM
                     ATRTLESEKDRRVTALIAPLMTCGAKLPIYALFVAIFFPHNAALVTTSLYLVGIVMAI
                     VVALFLNKTAFKTEAEPFILELPEYRIPTIDALIKNTWNKSKGFLIRVVTVMFAMSVV
                     IWGLSSFNVFGYTEDINVSFLATLGHIISPIFKPLGFDDWRTSVAILSGLGAKEIVVN
                     SLNILYGNLTVVLPTIFNGVTAYTFLIFTALYTPCIAALATMKKEYGNKMMFTSFAYQ
                     FILAWIMAFIVKSIGGVLFMGNSIMEALIGGIIIVLALFILFNKFKSTKNGNVCSGCS
                     ICSGCPSANSCSSKEDSNKKSNTH"
     gene            complement(26428..27483)
                     /locus_tag="PC466_002001"
     CDS             complement(26428..27483)
                     /locus_tag="PC466_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HDF2769385.1"
                     /translation="MTIQDYMLETPVRMREIISNADSLFNEVKRANLKKIIITGSGTS
                     YHSGVQVQPYLQNLLDIDVVKMYPFMITEDTFKFDNENTLVVGVSQGGSSYSTYNAMK
                     LAEDKGCKIASMAGCKNALIDEISDYILTVNCGEEKSGAKTKGYYCTKLNLMLLGLQI
                     AREKGTISSEKYNEEINKILDAINRFEAVYKLSKQWIERNKEKLVNSKEIRIIGHSDI
                     YGDTLEAALKLLETMRIPVTGYEFEEFIHGIYNAINSDSTIFILDTGKEPRVTKMIDV
                     LSGWTENVFAIGRDVTENDKNLKIDITDNPYYQTFNFIVPIQLICGEIPTLRGVDPSV
                     PKDTRFHMKLGSKKLNK"
     gene            complement(27531..28331)
                     /locus_tag="PC466_002002"
     CDS             complement(27531..28331)
                     /locus_tag="PC466_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HDF2769386.1"
                     /translation="MNKLTKKELRSMFWRSFALQGAFNYERMQNLGYCYSMLPAIKKL
                     YNKKENQAKAIERHLEIFNTTTVVVPAILGITAAMEEENANNPEFDESSISAVKTALM
                     GPLAGIGDSLFWGTFRIIAAGVGVSLAKEGNIFGPLLFLLLYNIPAFALRIFGLKYGY
                     KVGVNSLERIQREGLMEKIMSMATTVGLFVVGGMVATMLSITTPLKFNLNGAEVILQD
                     ILDKIIPNMLPLTFAFLIYYMLKRKVSVTKLTIGTIVTGIALHAIGLL"
     gene            complement(28324..29115)
                     /locus_tag="PC466_002003"
     CDS             complement(28324..29115)
                     /locus_tag="PC466_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF2769387.1"
                     /translation="MLVQATMLAIIAGVGILDGRIFGQSMFDRPIVTGMLVGLVLGDI
                     KSGIMIGAQLELIWMGIAGIGAATPPDVVTGGVLGTAFAILSGNGAEVALAVAVPVAV
                     LAQSLGVLVRIINSYFSQKAVFYAKQADFKKVTIMMWLPVILFFLSTSVPTFLAIMIG
                     ADKVTTLINAIPKVILDGLGVAGTLLPAVGFALLMDMLISKKMSVFFFIGFLLASYGG
                     LDITAIALFGVCVAFVLNFYINNKENNQNPQLAMNTLTEGEIDFE"
     gene            complement(29155..29577)
                     /locus_tag="PC466_002004"
     CDS             complement(29155..29577)
                     /locus_tag="PC466_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HDF2769388.1"
                     /translation="MKKFLIATHGELSRELVDTSKLIIGSLANIEYFCMTKDKSADDA
                     EKEIRSILSNNKDSEEFVVLTDVFGGSVANICTNLLLQGFKFELLTGVNLPMLLSIFL
                     LVEEDTKLIVKSGLEEAKNGIVYVNELLENRNKIKNVM"
     gene            complement(29593..30072)
                     /locus_tag="PC466_002005"
     CDS             complement(29593..30072)
                     /locus_tag="PC466_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2769389.1"
                     /translation="MVSLMRIDDRLIHGQVAYGWATSLGINVILVANDEAKNDQMKAM
                     SLNLAKPSNVTLYIRGVEESGEIVEKFASSKKSNVLVLVKNTRDALVVAKNSGGVLKE
                     INVGGLRYEEGKKKLTDLVAVDDDDINNFKEIGDLGIDIELRMLPRDKKKQLSDLIK"
     gene            complement(30204..32960)
                     /locus_tag="PC466_002006"
     CDS             complement(30204..32960)
                     /locus_tag="PC466_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2769390.1"
                     /translation="MRDEILSFVNECVLFNNFDELKKESGIITEDIVKKFNLSRTQSS
                     RLLNDLVKSDNLIKINSRPVIFLPKNKINDVVGPTKKSIYENLDELKNECKLLKQETV
                     FNSIIGYDNSLKEVIEQIKTAVLYPNGGLTIMLTGESGVGKTFLAKIIYKYSVSSNVL
                     EKNSPYNVLNCAQYYNNLELLSSLLFGHVKGAYTGANESRAGLIEQSDGGVLFLDEVH
                     RLNSEGQEKLFTFMDTGTFSRIGENGVIRKARVRLIFATTESLSKFLQTFLRRIPINI
                     YVPNIEERGTIEKRKIVEHFIYEESKVLGLPIEITQITLNTILKIKFKGNIGECKNVI
                     KYACGRAYAKNQRRNGNIFVTLQDLPRNLYIENVDIFQFQSGKSKSIIFSPKQFSIEM
                     SNGRNKRNIIYQSFIKCLDYFDRLEKNEITKEIFSKKSSNLMIRLMDNLVFSNNDENN
                     NVLMELIISIMQDIFRNLEVNNNIKYDGNNVLAFSSYLYLKDESYQLSDEYKALESKL
                     LIYLKKESYKEYSIISKISTLITNRLDMYLNNVDTIIMIIFIKSTIIRMKFNQVNATI
                     IAHGYATASSMANVCNRMLGKNIFTAIDMPIDATIADVSKQMSRYLEGDRIKNGLIVL
                     FDMGSLNLIYEDLKNKINGPMLFIDQISTISALEVGNLLMQGKNIEQIAEIMDEETKP
                     NIQLYYPQKNKEYAIISSCFTGIGTAIKIQHLLSESLIGIVDVKIIPYDYDSLVSMGD
                     KEPVFEMYDVMAIVGTANPNVNGVDFILLEDIISGKGEDDVFRIFSRVVENEKIKNIN
                     DSIVKNFSLIRVIDSLTILDSKKIIERIEEGINAIENIQKKKLPNDKKISLYVHLSCM
                     IERLVRQTEIEEYTDMDLLIKNHHSEVKLIKNAFSVLEKSYSVQIPISEIGYIYNIIY
                     GLPQ"
BASE COUNT        10669 a         5838 c         3665 g        12993 t
ORIGIN      
        1 ttgcttataa attttaagac ataaaattca tatattcaca acataaaata aaaatataac
       61 acatctgtaa agaattataa catcatattt gtatatatat aaagaaaaac atacaaaaag
      121 tatagaatat atactttttg tatgttttta ctaattctta tatttatttt attttagatt
      181 ctaaatttgt taatctttcc tcaacagatt taatcatctc ttcaaatttt tcttttttta
      241 ctttttcttc ttcaattaaa ctttcaggag cttttgctaa gaaaccttga tttgcaagct
      301 ttccattaac tctctttatt tcgccttcta actttttctt ttctttagac aatctctcaa
      361 tttctttttc aaaatcaact aattcattaa gaggtataaa tatttcaaca ccatcaataa
      421 ctactccaac tgcatcttct ggaacattag atttatcttt tgctatctct acatttgaag
      481 cagatgctag agttataaaa tagtctttac caagctcaat agcttctatt ttttcttcac
      541 ttgggattat tatcaattta gctttcttag aaggtggtac attcatttct gctctcacat
      601 ttcttatact tcttatacct tccatcaata agttcatcat atcttcttct tcagccatgt
      661 tatcttcttc attatatttt ggccattcag atactattat acatccttca acagtaggaa
      721 gatgagtata tatttcctct gttataaatg gcatgtatgg atgtaataat tttaatattt
      781 tttcaagaac ataagttaat gtatataatg ctgcagattt agcatttgca tcttccccat
      841 ataatctagg tttaaccatt tcaatatacc agtcacagta ttctgaccaa gtaaaatcgt
      901 atatcttttg aagtgctatt cctaaatcaa acttatccat gttattagtt gcttctttta
      961 caatattatt tgctcttgat attatccatt tatcagctag agttaagtcc tctttaacac
     1021 tttctctagt catgttttta attatatctt catcaatatt cataaataca aatcttgatg
     1081 cattccacaa cttatttgca aagtttctag caaattctac tctttccata tagaatctca
     1141 tatcatttcc tggggaattt ccagttgtta atgtaaatct tagggcatca gctccatatt
     1201 gctcgattat ctccaatggg tctataccat ttcctaaaga tttactcatt tttctacctt
     1261 gagaatctct tactaatcca tgaaccaaaa catggtcaaa tggcttttca ttcatacaga
     1321 acatacctgc aaatgccatt ctaactaccc agaagaatat tatatcgtat cctgtaacaa
     1381 gtacacttgt tggataataa taatctaaag cttcagtctt atttggccat cctagagtag
     1441 agaaaggcca taatgcagaa ctgaaccaag tatctaaggc atcttcatct tgtttaaaat
     1501 gagtgcttcc acatttagga cacttatctg gcatttttct agcaactact atttctccac
     1561 actcttgaca ataataagct ggtatttgat gaccccacca taattgtctt gatatacacc
     1621 aatctcttat attttctagc cattgtaaat aagttttatc aaatttatct ggaacaaatt
     1681 ctaattctcc ttttttaaga atatctatag ctggttttgc aagttcttcc atcttaacaa
     1741 accattgctc tgataatcta ggctcaacta ctgtatggca tctataacaa gttcctacat
     1801 tatgattatg cgcttttatc ttaattaggt aaccttgttc ttttaagtct gctacgatag
     1861 cttttctaca ctcaaatcta tccatacctt catattttcc acaaacttca ttcatagttc
     1921 catcttcatt catagtattt aactgctcaa gattatgtct taatcctact tcaaaatcat
     1981 tagggtcatg tgctggagtc atcttaactg caccagttcc aaactctaaa tcaacataac
     2041 tatctgcaac tattggaagt tctcttccta ctaatggaag tattgctgtt tttcctatta
     2101 aatgtttata tctatcatct tctggattta ctgctatacc agtatctcct atcattgtct
     2161 caggtctagt tgtagctatt tctaaaaagt cttcactatc ttttagtggg tactttatat
     2221 gataaaagtt tccgtcgtgt tcttcatgtt caacttctgc atctgataaa gtagttttgc
     2281 aatctgggca ccagtttatt attctatttc ctctgtatat gtgacctttt tcatataggc
     2341 ttacaaaaaa ttctataact gcttcattac acccttcatc catagtaaat ctttctttat
     2401 cccaatcaca agaatcacct agttgtttaa gctgattaga tatttttcct ccaaattcat
     2461 ctttccattc ccaggctctc tttaaaaatt cttctctacc tatttcatac tttgtcttgc
     2521 cttcttgttt ttttattctt tcaacaactt taacttctgt tgctatagaa gcatggtcag
     2581 ttcctggaag ccaaaaagct tcatatccat ccatacgttt ccatctgatt aatatatctt
     2641 gaagtgtatg gtcaagagcg tgtcccatat gcaattgccc tgttatattt ggtggtggca
     2701 tcattattgt aaatggtttt ttatctggat ttggtttaga tttaaaatac ccttcatcca
     2761 tccatttttt atatagccta gcctcaaaat cttttgggtt ataagttttt gataaattcg
     2821 tattttccat tgtcctgcct cctgtatttt ataaataaat tttttaaata tctttagaaa
     2881 taaaaaagag ctcttcatcc tctttaaaaa ggacgaaaag ctcgcgttac caccttaatt
     2941 ccaaagctta aaatacatta acatataatt aaattattag ttaatgttat tttatcaact
     3001 ttgactctca aagaatttaa cggttctaac cgtctaaact tacttatagt tcagtttaga
     3061 aactccaaag ctacattcag taaatcttat acttagaaaa tcttacagcc agtgaatttt
     3121 cctctctttt agtagtattt acttactcct cttcttctca gtctttaata ttacatatta
     3181 ttatatacaa atattattct ctttgtcaat tatttttatt ttattttttc tgaattttct
     3241 taattatgtc tattctcttt tatatagttg ttatatttta aaatatgttt ttacagttat
     3301 tctgtcttat aatgtcaata attgcaagat tattttattt taattttaat gctttctcat
     3361 taattttata ttatattatc cttacagtat acctcttatt cgtatttttt atattatatg
     3421 ttttatttta taaataattt actttatctt ttactatatt taaatttatt ataagttttc
     3481 ttgccagaaa tttttaggtg ttatattttc tgtaattggc aatattgtat atcctctctc
     3541 ttttaagatt cttataatat tatttaaagc atttaaactt tgctctttct catgaattaa
     3601 tactactaat tcatctcttt ttcttccata atataatata ttacttacta tctgacttgt
     3661 agaagacttc caatcctgtg tatccaaatt ccagtcccaa attaaataat catttgccat
     3721 aagtttatta tatgaacctt ctggcatata tggtttactt ccgtatggta atcttattaa
     3781 ttttgaactc tgaccagtta tttcttgtag agtattattg catgtattaa attccccaac
     3841 tgttacttct gggcttttat ataacttatg tatatcatga cttacactat gaaaacctat
     3901 tgagttttcc tcttccaaga ctctccttac ttcttccttg tgatttttca tattttgatt
     3961 aagcataaaa aatgtcgctt tgacatcatt ttcttttaaa atatcaagta gtgcatttgt
     4021 atattttgat ggaccatcat ctattgttat gtatgctact ttttcagaag tagcccctgg
     4081 accttttgtt tcttcttgag atgctttgta tatgatttct cctaaagtat tactttgaga
     4141 aagcagttcc agtgtatttt caccttttga acttatattt tcaactggaa cattattaat
     4201 tttttcctcc aataatgttc cagttaaaat taaaacagct ataagaaata tccttataaa
     4261 tacatgaaaa acagccttat tatctttaat tttcatcccc catatctccc ttttataaaa
     4321 gcataagttt aagacttaaa aagttatttt ttatatttat tctctttctt attacttttt
     4381 atatctctac taaatatttt tttaaccttt tcttcttctt tttctcctaa agattctact
     4441 cttttgattc ccaaagaagt taaaaattgt aatacattta aattatcaaa tggagtttcc
     4501 atattcgtac tttcactata ttcatcaaca ttcttagtac cttcttccac acttaaaata
     4561 cgcttcggac ctcctacaca gcctcctaca caccccattc cttctataaa tgtagcttct
     4621 atttctttat ttagaacttt ctttagaccg tccatgcact cttttgttcc ttcaaatgcc
     4681 ttttcttcaa attttatatt tttgtcaatt cttctgactg ataacttaac tgctttactt
     4741 acacctcctg ttctagcata aactctacct gaaagggacg cctctactct attactctca
     4801 tccattattg ctggatttaa ctctaatgca tcaaatattt cttgcaactc tttaaatgta
     4861 agcacaaaat caactgcatc ttttatatct tctaacattg cttctttctt ttttgccata
     4921 caaggaccta tgaatacaac tttagcatct ggatttaaaa tttttacagc tctcccacaa
     4981 gcaatcatag gagaaacgga tggtgataca ttctccaata tctgaggaaa actattttgt
     5041 atcaaactaa cccaaatagg acagcaacaa ctagttataa agcatccttc ttcgtccttt
     5101 ttcatatgct cataataatc atatgcttct tttgcagtaa gcatatctgc tgccaaagca
     5161 acttctatca tatcttcaaa tcctatcttt tttaatgcag ttcttaattt accagggctt
     5221 acatctttcc caaactgtcc tacaaaagct ggtgcaacta ttgcatatac agggctcttt
     5281 atatctttta acaattttat cattggtata aattctattt tatctgaaat tgcacccaac
     5341 ttacatcttg atacacaatc accacaagca ctacatacat cttcctcatt acaattaata
     5401 tgcttacttc ttatcttaca tgactcatct tccttattat tttcatcaca atatttgcaa
     5461 gcatctgata ttacagatat tattggtctt ttgacttcat ctaaatttac agcttcatgt
     5521 agtgactctt ttaaattttt atctgtatct tctgtcacat ccaatcccat agttacccta
     5581 attaaattta ccatagtatc tttatcaaat tttccactaa aataattatt taaattatcc
     5641 tttaaatctt catttaaaat tttattaggt aagttttcaa tatcctctat atcatcattc
     5701 cacactgctt ttacaagttc gccaaaaagc ttcattttat atatttctag tattttagaa
     5761 ttgtcatttc tagtattcat aaaaaatagt acctccataa attaaactta tatatgttta
     5821 atatttacaa agatactatt ttttatttat tatttaacta ctattattaa tatgatttat
     5881 ttagctttct caacaactct atttcaatca ttattttcat tagatgatag ttgaatacgg
     5941 ggcttttttc ttcatctata ttccagtcta gcttatccac attatatgtt ttcttaaggt
     6001 atttatatgt atgctctttc aaataaagtt tattttcaag taactctata gactgcatat
     6061 gaaaatgtat ttctctacat atccttaagg cattctcaat tttttctata ttagtttcac
     6121 tcaaactata atccaactca tcaataagtt ttgaatatat ttcttctaat ttttctactt
     6181 cttcttcaaa tttctctaca tttaaatttt cttttctaag aattttatct tcaataagta
     6241 acattgaaag ttcttctatc tttttaaatt catctataac actatttaga taatttggtc
     6301 tagccacata ataattaaca agtactccaa acaaaacacc tacagatgta tctaacactc
     6361 tatgtaaaga ataatacaca gggtcactat ttcctacacc tagatgtata gccagaaagg
     6421 ttacacaggc aactactact gactttattt taaacagatt gcataaatat attgagcaca
     6481 ttactcctag accacataaa aaagggtctc cagctttaat gatggcaaat atgaatccta
     6541 ttataccacc taaaatagta ccttccactc tattgattcc tgtctttaaa gaacctttta
     6601 ccgtatcttg aacagaaatt atacatgcta ctagagaata aaacatattc tctactagat
     6661 agttaccaag aatcatacat aaagtgacac taattcctgt ttttatagtc ctcataccca
     6721 tcttttgaag tttcaaagtt ccacctccta aaaagcacct tatataaaat acgcatcctc
     6781 atatttaata tgttcctagt atatcacaat tttttaaatt tacccattaa tcatattttt
     6841 ttatcaattc tttcttaatt tagacaataa aaaaactgct ttaaagcagt tttttatcct
     6901 atctcaacca ttttaccctc aattgcaaaa attatcttct cacatacatt tgttatatgg
     6961 tctccaattc tttcaaggta tcttcctata agtagaagtt ttactccttg gtctatagta
     7021 tttgaatttt catgcattat ttttaaacaa tcaatttgta cttgttcata caatccatct
     7081 acaatatcat ctttagttcc aacatcataa gctatacttg catcaaataa gattaaagct
     7141 tctctagtct gagacatcat agacttacat tcttttgcca tcttaggaat atctatcagc
     7201 tcttttatat aagcctctcc acctatcttc aacatttctc tagctatatt tgctgcataa
     7261 tctcctattc tttccaactc tatcgatata ttacctaatg aataaataaa tcttaagtcc
     7321 cttgccattg gttgctttaa tactattagc tctatactct tatctcttat ttcttctctt
     7381 aatttattta tttcttcatc atcttctact acttttcttg caccctctaa atccttctct
     7441 atcatacaag tcacagactt ttctattgct tcttcacatt tttccatcat aagtactgtt
     7501 tgttctttta aagtatcaat acttatatct aaactattat tgaccattgt ctaactcctt
     7561 tatagttata tattttaacc aaatctacct gttatatagt cttctgttct tttatctaca
     7621 ggagtggtaa acatagtttt tgtatcgcta aattctataa cctctccatt taagaaaaaa
     7681 gctgtttcat ctgatatacg agcagcttgt tgcatattat gtgtaactat gactattgtg
     7741 tagtcttttt ttaaatcctc tataagttcc tctactttta atgttgaaat tgggtctaaa
     7801 gcagatgtag gttcatccat aagaataact tctggtctca tagcaattgc tcttgctata
     7861 catatacgct gttgttgacc accagaaagt cctagtgcag atgatttaag cctgtcttta
     7921 acctcatccc aaatagctgc accttttaag ctttcttcta caattttatc taattgcttc
     7981 ttatctctta gtccatgtgt acgaggacca tatgccacat tatcatatat actcatagga
     8041 aatggatttg gtttttgaaa taccattcct actttagtac gaagatttat aacatcatct
     8101 gaggtatata tgtcctctcc atcaacagaa atgtttcctt taattgttac atcttcgatt
     8161 aagtcattca ttctatttaa cgttcttata aaagttgatt ttccgcatcc agatggacct
     8221 attaaagcag taaccttatt ctcttttata tccatattta ttttctttaa tgcttgctta
     8281 tcaccataaa ataaatccaa atcttttaca ctcattttta tcttatcgat taattccatt
     8341 attcacacct cttaaattta ataattagct ttatttaatt tcttagcaac aaatcttgct
     8401 agcatgttta gtgctaatac aattactatt aaaacaattc ctatactggc tgctgttgct
     8461 atatctccac tctctttagt cagtaagtat gagtgtacag ttaatgttct tgcactatca
     8521 aatattccac ctggcatctt ggctacagta cctgctgtaa gtaatattgc agctgattct
     8581 ccaattatac gaccaactga taagattact ccagataaga ttcctggtat tgcacttgga
     8641 agtactacct tatataaagt ttgaaatttt gtagctccta atgccaatga tgattctcta
     8701 taagcttgag gaactgtttt taaagcttct tctgttgtac gaattattac tggtaatatt
     8761 attattgcaa ctgtaagtga acctgcaact atggaatatc ccatttttaa tgtaactaca
     8821 aagaaaattc ctccaaataa tccatatact atagatggta tccctgataa actttcagtt
     8881 gcaaatctta tagctgtaac tgcttttcct tttttagcat attcttgtaa atatatagca
     8941 gccaatattc ctataggagt tgctacaact atagaaacta ctactgtata taatgttgta
     9001 attatcattg gaagtatacc accatcacct gatgctgaat aattgctaaa taagaaatta
     9061 aaattcatgt tgccaattcc ctttataaat ataaatccca ctataatgac taatgatact
     9121 attgtaaata gtgctgatag atatactaat gacttcaata gattctcttt gaactttctc
     9181 atcttaattt accgccttat ttgaaagttt atttaaaact aagtttaaaa ttaatataaa
     9241 tgtaaacaat actactccag ttgcaaataa catttcttga tgtgtaccaa atgcgtatcc
     9301 catttcaagt gctatattag ttgtaagtgg tcttacacta tctgttattg cagttggcat
     9361 aactggtgag tttcctgcaa caagtattac tgccattgtt tcacctaaag ctcttcctac
     9421 tcctaatact actgcagcta atactccaga tttcgcagca ggtagtacaa ctttgaatat
     9481 tgtttctatt tttgatgcac caagtgctaa tgaaccttct ttgtatgctt ttggtactgc
     9541 tcttattgct gtttctgata cagatattat tgttggtaac atcattactg ctaatactat
     9601 tactattgct aacaaacttt gaccttttgg aagattaaat atactttgta tagttggaac
     9661 tatcactgca agaccaaata caccatataa tactgaaggt atacctgcta aaagttcaac
     9721 tgctggtgac attatttttg ctaatctttt aggtgctact tctgctataa atacagaggt
     9781 taatatacca acaggtactc ctatcacaag tgctccaagt gttgcaaata ttgatgctac
     9841 tatcatagat gatattccaa atttattggc agaaggaacc caatctgcac cagttaaaaa
     9901 gtctataaat gaatatcctt caaatataaa tggtcttaag cctttataaa atacgaatcc
     9961 tattatcaaa agtaaacttg caactgctac taaagcacta agtagaaaaa tattttttgc
    10021 tactttttca attacgtatt ttgtcttatt gccattattg tcattttttt ctaaacctac
    10081 taatctagat tttactatca taataccctc ccattaaaat atacttatcg attttcgttc
    10141 tgtattcaaa atttaatttt ttataattcg tcttcatcaa atttcctgta cttttattct
    10201 acttttttta agttaaatct atattaggat taagttaagc aagtgtaaaa ttatatttac
    10261 ttttttaaca ttaattttac ttttaaaact atatttgaca tttactttac aatatactgt
    10321 tgtttctcta tattaaaata gcagatatag ataataatac agtttatgta taatttatta
    10381 cctatatctg ctattaagat ttgttaacta aatttaactt ttatactaca tatataatta
    10441 tcgtatcctc tagtttatat cactattatt tctatcaaat tgttatgata cttgatgttt
    10501 gcaataggta cgaatagcca aaaatataaa aataggtatt tctatcactg agaaaaacag
    10561 tataatgtgt ggtgtccaaa aactcatacc tcctaagtgt aagaaattaa atgatgtcat
    10621 ttgatataat aaactaatct taagaccaat tccccctggt ggtaataggt atccaatcca
    10681 actaacacct attcccatag gaattaagca aatagaaaaa gcaatcagca tagaagtaag
    10741 agaatcctta cattttgcag ataaaaataa tgttaaacta accattgcaa gtattgaaat
    10801 tagaccacca atagctataa gaatctgtgc ttgtagtaaa tttatattta ctagactaat
    10861 gacagaaaac aacatttgaa atgaggtttt caaacattca gtaccaaaag ctaaatcaga
    10921 aattgccaaa tggatagaaa tacatacaac aaacattact ataaatatag aaaatagagc
    10981 taatatttta gtaaacgcta gacgagtatg tccatgtttc gtacaacgaa ggatgctatc
    11041 tgattgtgtc tgatactcac cagaaaaagt aggtgcagta attgcaacac atataattaa
    11101 taatataaaa atgtaaaata ttatataatc gaaagcatct ttagaataac ctgggtatat
    11161 ctcaaatgga gtatctactt ttctataaag ttcttgagct ttcatttgtg cactggaagt
    11221 ttgtcgttca atcttcataa tatcatttaa atgagttttg cattgttcat aaaaagaatc
    11281 taaatcattt gtatttattt ctgataattc tgttgcaaat cctgtttctg aattagcaaa
    11341 tgcttcagga agtctattca acaatgggcg tattggtaaa atacttttag aataaatatc
    11401 tagtgggaaa tcttcactac ctactttacc atacttttct tctgtttttt tccatatatt
    11461 taaagcatgc tttaattttt ttggtgttac aactccacta ctaatttcac tattattagc
    11521 ataaattgtt tttttatatt taatagcatc taaaccactc aattcaacta ccttgccatt
    11581 attatctaaa taattgatac cctcgtaagt aattggaaga aaagccatca atgcagataa
    11641 aaccaatgcc aacaataata aaattaatgt acgacgtgag tgcaacactc gtttaatttc
    11701 caaataaaaa atacgcattt atttcccctc cttactataa actgcttctg gaaataacca
    11761 taaatataaa tcttctagtc gtggttcaac agcaatagag ttatcaattt gtgacttttc
    11821 tgccaagtaa cgaatagata cttgattgtt tttttcacta cgctgattga ttatacgtaa
    11881 attcatttca tattttgaaa tatctctatt tgatataaga cattcccata ctttgccctc
    11941 tactttctta accagtttat cggttgttcc cacatcaaga atttttccac ttttcataat
    12001 agcattttga gttgatatgt actcaatatc agatacaatg tgagtagata ttaggacaac
    12061 acgattatga gaaaattctg aaataaaatt acgaaatctc actcgctcac cagggtcaag
    12121 ccctgctgtt ggttcatcca ttataaggat tttagggtca tttaacatgg cttgtgcaat
    12181 tcccactcgt cgtttcattc caccagataa tttaataatc tttttatttt ttacatcaga
    12241 taatgtaaga atttccaata gattattaat ttttcctttt acttctcttg gtggtacatc
    12301 tttcaatgct gctatatatt ctaaataatc ttttacagaa aaatcctgtg ggaaaccaaa
    12361 ttcttgtggt aaaaatccca gtaaatttct gtactcagca cccattatat aaatattttt
    12421 tccattatac agaattttgc cattggtagg tttcataatg tctgtaataa ttctcatcaa
    12481 ggtagtttta cctgctccgt ttgctcctag aaatccccac acacctggtg ttaaggtaag
    12541 gcaaacatct tctacagcaa ttttatcctt aaattttttt gtcacatgtt caatttttaa
    12601 ttccatattt gaaactcctc tctttatcta cttacctgca aaaacaaaag tgtcttgctt
    12661 agtatttatt ttactaaaca aagacactca taattttaat attaaataga taatttctta
    12721 agaaaatcct aatatttgat ttatatttta ctaaatagat gtaggaagcg atatagtaaa
    12781 tgttgtgact tcatctttac tttgaacagt aatatcacca ccatgcaaat ttataatttc
    12841 cttagctata gaaagcccta aacctgcacc acccatatca gattttctag cttcatctaa
    12901 acgattgaac ttttcaaata tagcagaaag ttgttcttct ggaattgtct gtccataatt
    12961 tctaaaagca atatctacct tgctgtcttt atgaaccgct gagataataa tttctgtatt
    13021 aggatagctg taagcaatag catttttcaa gatattatta aacactcttg caagtttttc
    13081 agaatctgct tttattgtta aactttcatt tgcttttaga atggctctat ttcctttttc
    13141 agacagcaat gggtaaaatt catcctttaa ttgaagtaac atataatata ggtctacttt
    13201 ttcgaaatta attttgattt gattagaatt atatcgtgtt atttcaaaaa gttcattgat
    13261 aagtttttct aaatattgtg ctttgtcaag tgcaacttca gtatacttag atttttgaga
    13321 attatccata ttaggtattt cttttaataa gctcaaatac ccaataactg aagtaagtgg
    13381 tgtccttata tcatgtgcta gatacatcac aaggttattc tttttatttt cagcctcttt
    13441 cactgcttgt tgacttaaca aaacagacat cttaatttgg ttcatttgtt gctctatttc
    13501 ctttaatggc ttagatagtt caaccaattc atcattttgt tgataaatag tatgtgttgc
    13561 attgatgatt tctcttaaat aattccatgg ttttttccaa taaaaattga aaatagtgat
    13621 atatccaatt ataaaaacca aaaaaaataa tacatctctt ctcaacttaa gccatttaac
    13681 aagaggattt gaaaaatttg aaaacgtata atcagccata aacattaaaa ccaatactat
    13741 acctgtatag atagctaaca ttatatataa tttatacttt aaatacgcct ctgtattttt
    13801 ttctcttttt ataaatttat atttatctct tagtttccta taagtaaaat tattaatctt
    13861 tttcataata ctacatccct tcttgacaag aaaaataggt gtcaaatctt gtaaccaaca
    13921 ccccaaattg tttttatata ttttgcttca tctacagtat cacctaattt ttcacgaaga
    13981 tggcgaatat gaactgttat agtattgtta cttttattgt aatattcatc tttccagata
    14041 gcatgaaaaa gattttctga atttaccaca gagcctttat ttttcaataa tacatgtaga
    14101 atagaaaact ctgttggagt aagtgaaaga gctttaccat ttaaatggca ttcatatgtt
    14161 tgggtattca attccagacc taaaaaagaa aaaatatgtg aaagttcttc accagattgt
    14221 aaacttccac tgtatttctt atatcttcta atctgtgcct tcactctagc aacaagttcc
    14281 aaaggtcgga aaggtttagt aacataatca tctgcaccta aagttaagcc tgtaatcttg
    14341 tctgtttctt catccttagc tgttaacata atgattggat aagtatattt ttctcggatt
    14401 ttttggcata aagaaaatcc atttactcct ggcaacataa catctaaaat tgcaaggtca
    14461 aattcattta aattaatgca gtttagtgca tcaagaccag aataaaattt ataaacaata
    14521 tagttttcat ttgtaaggta gacttctatt aaatcagcta tatcacgttc gtcatctaca
    14581 actaaaattt ttccactcat agactttaaa catcctttct atatatattt atatatatta
    14641 tactaaattt aattttttta tatgattttt tacattagaa tttattaaga aattcttaat
    14701 cttattatgt aactatttta ttatttaaca tatattaaag ataaaaatga atatatatag
    14761 atttagatat acaatttatc tatcttttca aatataatct ataaaataat agttctgtta
    14821 cgcatttttt catataataa aactgactgt aatttaactg gcaaagtcta gaagaatagg
    14881 ctttatcaat taaattacag tcagctattt tataataatt tagtttagat atcgttagca
    14941 tttcacattt ataacaatta ttaatgagat taatatattt attattcttt attaaaataa
    15001 tatcctgctc ctcttattgt tataattttc tgaggatttt tataatcttt ctctattttc
    15061 tttcttaatc cattcactgc aactaccaca ctatagttat cctctaagta ctcattcatc
    15121 catacatgtt catatatctc tttagtagtc agagtctttt caggattctc tataaaaaag
    15181 tttaacagct tattttctgt tggagtcaat tttattattt tgtcttctaa ctttattact
    15241 ccactagttc tattatattc ctctaatttt gtattatttt cattattatt tacatatgag
    15301 ttcattcttc ttaaaatagc ttttactttt gcatataata tttctaaatt tagaggcttt
    15361 attaagtaat catctccgcc agaatttaaa gcatttaaaa tgctttgttc ttcatttata
    15421 taagtcatat aaacaattgg acaagtagtt acatttctaa tttttttaca aagagtccat
    15481 ccatcaccat cagttagaat tatttctaaa aatattaaat catatttatt gctaaatatt
    15541 tttccaatag cttcttcaca attatatgct aaatctatac ttatttcttt ttcctccaga
    15601 aatcctttta gcttctggca attatccttg tctccatcta ttatcaatat cttagtttgc
    15661 attataatca ctcccaaata tcattattct tttatattaa ataagctatt attataaaaa
    15721 acatagactt aattttattg taaaaacagt tccttttcct agttctgaat ctacaaagat
    15781 ttctccgcca tgctctctta taatggattt gacaatatat aaccctagcc cttgcccttt
    15841 tggctcatta ttatctcttt ctgtaaagaa tctgtcaaat acctttggta tattttctgg
    15901 aggtatacct tttccattat cagaaacttt aataattgca aatccatctt ctttatccat
    15961 tgataaaatt atctttccat caaatggagt aaatgtcaaa gcattataaa ttaaattctc
    16021 aaatgctctt gtaagcatct ctttatttat ctttgcatat atttttttct ccaatatgta
    16081 agtttcaaag tttacaccac atgcttgtgt atctggcaag ttattttcat atatctcttt
    16141 aataaaatca tttagacata ttttttcact aataccaatg cttttatctt gtgatgtaaa
    16201 ttcttgcaaa ctacgtactc tattttgtac ttcatttgac ttttgattta tagcataaag
    16261 ataggttctt gtctcttcat ctacatgaat attaccaacc tttatcaagt ctataaatga
    16321 ttgtatagct gaaacaggtg cctttaaatc atgtgccaca tctgccaaga attttttacg
    16381 ttcatttaac aatgttgtaa gttcattagt tctcacttca acttcatgtt caagattcct
    16441 tgtaagtttt tcattctctt ttattattat tctattcctg tttatcatca taagagaaaa
    16501 taaaataaca attataaatc cacaatattc tgtttgccac cctgtaaata taggctcaaa
    16561 tctattacta gtaactgcat caaataatat gctaattcca aaaacagtgt ttactgaaac
    16621 taaaatataa gaacttatat gctcagagca tgtcttttta tatattgaaa ccagcgaaga
    16681 cattaatata tatataaata caatatattt atatatgtct attaatttcc catatatgtt
    16741 gacaaagtac atatcatatg gaagaagaat aattggtatc actatagata tgatactcat
    16801 tgtaattcct aatggtaaaa ttaaaaatct atacacttta tcttcttcta ttttggatat
    16861 acttccattt atacaaataa tacataaaac taccataaaa taggacgaat cttcaaccgc
    16921 atatgtaaag cttaccaaag gcagtcctaa caaatgtaca aagggatagg atacatggat
    16981 ggcaaagaaa acacacatac atccaaaata taagtaaagt ttacttttgt ttgaaagaaa
    17041 ccatacagac aacgaaaata tagctattgc aaaagttgtg aagcaaatta tactataaaa
    17101 aagtaatcga taaaacatca tattacttat gtcctttgtt tctcctaatg caggcggata
    17161 atacaaacca ctataataat gtgaaaaatt cgatacattg attataattt ctgtatcttt
    17221 ctttgcaata aaacttacta ctgaattttt aattttgggt ctatattttt ctgttcctac
    17281 atctcctaat ttagaaacta tttctccatt tatccatact tcacttgcgg aaaaaatctc
    17341 aggaagctct aaacttagta gcttatcctc accttcattt tttattctca tacgataagt
    17401 agcattccca tatggtgact gattcccttt tctcatagaa aaatctggat attgacctat
    17461 aaaaacatat tctggtttta tatcttgctc tgtaaaatca ttcggtttaa atattttatg
    17521 attataaaac tcccagtcat ctatcagaaa gacaagttta cctttagtga aagtatcatt
    17581 atctatagtt aaaattccat tacttgctct aatagactta tatgtatatt tattatcata
    17641 tttatacaga agatttaatc ctgctattgc caacagagag actatcaata caatgagagt
    17701 tccttttagt atattatact ttttcattgc atcaaccaca tctctttcat agtagtatta
    17761 aataaaacaa gaactattta ttaattacag tatctcactt atggtacaaa cttatatcct
    17821 tttccccata cggtttgaat gtattgatgc tccctgctta aagaattaat tttttttctc
    17881 atctgtgcaa tatgaacctg cactgtatgt tgatctccaa tatcaggcat tttccaaact
    17941 tggttatata tctctatctt cgaaaatact tgttctttgt tttcagctag aaacaataat
    18001 atttcaaatt ccatagtagt taaatctata ctttctccat caaaagttac ttttcttgaa
    18061 tttacattta ttactaacgc tgaaaacttt aacacattag gaactgatgt aatatttttg
    18121 tactgcctca tacgagcata tattctaagt tcaagttctt ttaaactata aggttttgtt
    18181 atataatcat cccccccagc taaaaatccc cgaacttttt cttcttcatg ctcataatta
    18241 gataaaaata ttataggtat gttaaccttt tcttttatat cattgcacat tttatatcca
    18301 tctatatctg gcaatgaaat atccaaaatt atacagtcta aaactatacg ctctactata
    18361 tccatagcat ctttagcagt ctctgatgta tatacattaa aacctatatt agaaaaataa
    18421 atttgattta tatttaaaat atcaacatca tcatctacaa ccagtaaatt atacattaca
    18481 ccactccatt caaaggtatt ttaatcataa tctcaagttt tataattatt acaaattata
    18541 atgttttatt ttcatatata actagtatta ttattttata atatctttac aaactagact
    18601 ataatactta agtatttttg aacaattctt gaatattgta ttgaacatta agatttatta
    18661 ttaaatacta attaaagtct ccgattgttg gagaatggag cttaaagtca ttttcactta
    18721 taaatttatt atttttctag aaacttgtct attggctagt ttgagtattg atttatatga
    18781 tttatatggt tataatataa aataaattgt attattttgg taaatatatt gttacaaaag
    18841 gtttatattt tgcatctcaa tgtttataaa aactttattt tcttattata atagtattat
    18901 actttttaaa aaatttccct tttccaacaa atggctactt taaaagccaa aatttcacct
    18961 atcaataaaa atcttaacga ctaatactct tattttcaaa ttttgcaaca tttttgttaa
    19021 ttttaaagca aaaaaagact atgcaatata aaaattatat tcatagccgg ttgcaccact
    19081 aactccatat atctccagat gcccaataat aagatatact tctcagtttc taaaatattt
    19141 ttattaaaaa tcttttatat attttcataa atttcttttt tattctaaca ttgtaatatt
    19201 attttgtcaa tatttccata tttttagata taagatacta aaatacctat tttatctaaa
    19261 gatatttata tttctacatt caataataga caataccctg caagttaaag catcattttt
    19321 atgagcttat ctcacagggt attatatgtt tactttatat tataattcat gttattgatt
    19381 aactttaata aatccttttt ctgaaacaag tgcttgtcct tcatcactta atatataatc
    19441 tattaaagct ttcccttttt ctgacaaacc atcttcttta ttaactaata taaatggtct
    19501 tgatattgga tatttattag ccattacatt tgcatcagtt gcttcaacat catttatttt
    19561 taaactattt actttctcat caacatatcc aaatgatata tatcctatag cattttcatt
    19621 tccttcaact gtagttttta tatttcctga accatcactt atttgtgcat ctttagttag
    19681 ttcttctgaa tcaaacccta caatttcttg gaatccatct ctagttcctg aaccttcttc
    19741 tcttgatact attactattg gtgcatcatt tcctcctact tctttccagt tagtaatctt
    19801 tcctgtatat atacctttaa cttggtccat tgtcaggttt tttactgagt ttgcagtatt
    19861 agttatcaat gctataccat ctattgctat tttagtttcc tttaatccag cacttttttc
    19921 ttcatctttt aaatctcttg aactcattcc tatttcagat gttccttcta tggcattttt
    19981 tatacctccg gaagaaccaa tctgttgtac ttctacacta acaccttgat ttttttcttg
    20041 aaacttttct ccgatagttt ccataagagg acctattgaa gttgaacctg aaacagaaac
    20101 tttgcttgaa tctcctgaat cacctgaacc tcctgagtta gaactacatc ctactgctaa
    20161 agctccaact aacattgtac tagctaaaag aacgcctatt ttctttttaa acattttact
    20221 tacccccgct tatattttaa ttttttgttg tcatttttct atattttaat aatacagatt
    20281 ctttgttaaa tgaatattag agcagggtta agtaaatgta aatattgtta aatacatgta
    20341 aaaacttaat tttatatgat ttattcttaa ttagattaac tttttaaagt tactttaggc
    20401 agatataaac acaatacaac tcatattatc agaagtcttc attgaagcta tcaacctatc
    20461 acatcctata attctttttc tagtttatta actaattcag caaatacatt taaggcttcc
    20521 tctatagatt cttttttagt catatctaca ccagcagatt ttaattgttc tagtgggtat
    20581 tctgaccctc cactttttaa gaagtttata tatctatcta ctgcagtact tccttctgaa
    20641 agtatctgtt gacttaaagc acttgcagca gaaaaccctg tggcatactt atatacatag
    20701 aagtttgaat aaaaatgagg tattctcgcc cattctattc ctatttgttt atctactatt
    20761 gcagattttc cgtaatactt ttcatttaat ttgtagtata tattagtaaa ttcatcagca
    20821 gtaagtggtt ctccactctc taccctttga tgtacaattt tttcaaattc agcaaacata
    20881 gtttgtctat gaactgtagt tctaaattgt tctaaataat aatttaataa gtatatagtt
    20941 tcatccttag acttagaatt ttctaataaa taatttataa gaagtaattc atttaatgta
    21001 gatgcaactt ctgcaacgaa tatcttatag tccgaatata aaaatggttg acttgttctt
    21061 gaataatgac tgtgaacaga gtgccctaat tcatgaatta aagtgaatag agaattaagg
    21121 tcatttttat agctcattaa tatataagga tgtgaatcat aacttcccca agaataagct
    21181 cctccttttt taccttcatt atcatataca tcaatccacc cttcatcaaa agcacttttt
    21241 atgaccttca agtatttttc tcctaaaggt ttaagtgcct ctaatatgat atcctgtgct
    21301 ttatcatatg gtatatccat gtcaaattta tctgtcaaag gaacatacaa atcatacatg
    21361 tgtatttcat tcaatcctaa aaatttcttt ttaagctcaa catatttatt tagattagga
    21421 atacttttat ctatagctga tataagatta ttgtaaacat ctaaacttac atcatctgaa
    21481 aataaagacg cttctattgc tgaattatac tttctagttt ttgcgtaaaa tatctctgat
    21541 tttattccac cataaagcgt tgaggcaaat gtatttttat atttctcata tgttgaaaat
    21601 tcaccttcaa aagcgtcttt tctaactcta ctattcttac tttttataaa taaagagtag
    21661 tttgaatgag aaagcttaac cttattaccc tcctcatctt ctatctcagg aaattccata
    21721 tctgcatatg ctaacatatc gtatacattt tctggaattg tcgataattc tgatgtagct
    21781 gcaagtattt cttcctctcg ttcactcaaa gtatgtggtt tatctctcaa tatatccttt
    21841 atatattttg tataaaagga tagcttctca tcttttaagt attcacttaa cttattctct
    21901 tctatcgcca gtatttctgg aactatataa gaagtagcca cacctaaatc agtagataac
    21961 atttctgtct tagtggctct tccttgatta tcattaattc tagtatcttc atgttgtttc
    22021 atatgagtat atacatataa attttgaaca atcctagatg cattttcaga gatatttaat
    22081 actttatata agttctcctt actctcagaa agcttccctt tatattcttt tacttcttgg
    22141 ataagatttt ttactttact tatgtctttt tcaatttcct ctttactgga gtacatctta
    22201 tctatcttcc atttgtactt ttcttctatt gtacttctat cagttcccat atcatacacc
    22261 tctattttaa tttgttttat attttattca ctttacaaaa tatattgtat atattttagt
    22321 ccaaataatc tacatttatt actccttcta tcatatttat ttctttcata acgtcgtgta
    22381 agtgtattct cttagcataa gatacaaaaa aattaacctt ccagtattct tcattacgac
    22441 attctatttc catatttctt acgataagtt gatttttttc aaatttatca tataaaaaag
    22501 gtatagagtc caaattgctt aattttaata tcaatacatt cttttcttgg ctaaataaaa
    22561 acgtattgat tatcctaagc acaaataatg ctatcattac aaataatcca cctagaattg
    22621 ccaattcata ataaccatat ccaactgcta taccaataca tgcagttgcc cacatcccag
    22681 cagctgtagt aagccctttt actccacctt tattttttaa aattgctcct gcacctaaaa
    22741 aaccaattcc agataatact tgagcaggca ttcttgctgg gtcagcattt gtatacaaat
    22801 tataatcaaa gaataattga atcgaagtta ttgaaacaat acaagaacct attgcaatta
    22861 gtatatgtgt cctaaatcct gcaaactgtc ttattttttc tctctctaag cctattattc
    22921 ctcctattat tagtgctaat agtaacctta ttgctatctc cttacttcct atatcaatca
    22981 taatataaaa ccctcctgac ttaattacaa cttatgtcct acagataatt tacacatcag
    23041 aaatactatt ttatatctta atattattat taatatatgt aaaatatagc catctgttaa
    23101 tttttgatac aaaaaaaccc acaactgtgg gctatttgct taggtacatg tatttattta
    23161 ttaatatatc tattttctta cttgattcta ctaactcttc ttgaaatatt tctggatatt
    23221 ctatgtatgt atttatctct tccctaactg cttcaatctc attttttaac gcttctaatt
    23281 cattgttcgc cataataatc accactatta caaatttgta tatttttata tacattttat
    23341 caaacaatat tatattttgt caatattatg tcaataaaac ttactataaa aatgctttaa
    23401 tttaggtatt gtatacctgg atactaagcc tacaaacata ccagttacta atgatgccat
    23461 taacataaat ggtaagtacc ctatagcaag tatattttct atgattaaac ttgcaactat
    23521 taattgacct atattatgcc ctattgcacc tataatgctt atccctatta gtgataaatc
    23581 ttttatttta ctcgctaaat acataaataa aagactcaga taagctcctc ctatactaaa
    23641 tagtagatat gataaagggc ctgcaaatat tgatgacaaa attaccctga tagtaacaat
    23701 tataacagta tctttgacac ctaacaacat taatgaaatt aaagttataa tattgctcaa
    23761 acccaatttt gcccctggaa atataactat aagaggattt ggtatatatg tctctagtac
    23821 atataaagct aaactatacc ctatcataag acctaaaaat gtcatttttc tagttttcat
    23881 taagttaact cctccaaatt ttatctatca tcttacatta taatacaaaa tatataaaaa
    23941 cacctaattt agactaaaat atttttaatc tatttagaat aaatattagt tatttcaatg
    24001 tgcaattacc tctataaatc ttgacttttt gtatcatact tgttacaatt ttaatgataa
    24061 tgaatttcat taggaggtgt taataatgac tgtttacgat ttaaaaatag gagaaaaagg
    24121 atttattaat agtatagatg gagatattaa attatctaaa agattgcttg cacttggatg
    24181 tataaatagt actgaaatag aagttaaaaa ggttgcccca cttggagacc caattataat
    24241 tagatttaga ggctttgacc ttgcgattag aaaatctgat gctaaaaata tttctttaca
    24301 ataatagagg aggagctacc cgtgattaat gtagcattat taggaaaccc aaatgtcggt
    24361 aaaactactg tttttaatct acttacaggt tcaaatcaat atgtaggtaa ctggcctggt
    24421 gttactatag aaaaaaaaga aggatttctt ggaaaagaga taaaggttgt cgatttacct
    24481 ggtatatatg caatggatac tttctcaaat gaagaaaagg tttctaaatc atatttagaa
    24541 aatgaagatg ttgatgtaat agtaaatgta gttgatgctt ctaatttatc aagaaacctt
    24601 tacttaacaa ctcaacttat gcaatttaac aagcctatag ttatattgct taatatgtta
    24661 gacattgcag aatctaaagg agttaatata gatgccaaaa aattaagtga agaacttgga
    24721 gtaattgttg ttccaattat agcaaaaaag aaaaatggtg ttgataggat agaagaagag
    24781 attaagggag ctacgcaaaa agcttttata tatcagaaaa actttggaag tgaaacagaa
    24841 acatataaaa aattagaatc cattttatcg agatgtacaa aaactacata tacacaaaag
    24901 aaatctatca gtgataagat agacaatata gtcttgaatc ctatattagc atatccgata
    24961 tttattggtg tattgttcct cttatttaaa tttacctttg actgggtcgg aggaccacta
    25021 caagagggat ttgctagtct tatagaggct tatatttctg cacctgttag tgatatgtta
    25081 tctaactcta gcccatggtt taaatcactt atagttgatg gaataattgg aggtgttggt
    25141 ggtactttac cattcttccc tttaatattt acattattct ttggtatatc gttgtttgaa
    25201 gatagtggat acatgtcaag aacagcattt ttaatggata aagttatgag aaaggttggt
    25261 ctatctggta aagcttttat acctatagtt atgggtatgg gatgttcttc tccagctata
    25321 atggcaacta gaacattgga aagcgaaaaa gatagaagag ttacagctct tattgcacca
    25381 cttatgactt gtggagcaaa gctacctata tatgcactat ttgtagctat attctttcca
    25441 cataatgctg ctttagtaac tacgtcactg tatttggtgg gtatagttat ggcaattgta
    25501 gttgcattat tcttaaataa aacagccttt aaaacagagg ctgaaccatt tatattagaa
    25561 ttaccagaat atagaatccc tactatagat gcacttatta aaaatacttg gaataaatca
    25621 aaaggtttct tgataagagt tgttactgtc atgtttgcaa tgtcagtcgt aatttgggga
    25681 ctttcttcat tcaatgtttt tggatataca gaagatataa atgtaagctt cttggctact
    25741 ctaggtcata ttatatctcc tatattcaaa cctcttggtt ttgatgattg gagaacttca
    25801 gttgctattt taagtggtct tggagcaaaa gaaatcgtag taaactcttt aaatatacta
    25861 tatggtaatc taactgttgt cttaccaaca atatttaatg gagttactgc atatacattc
    25921 ttgatattta ctgctttata tactccatgt atagctgcac ttgcaactat gaaaaaagaa
    25981 tatggcaata aaatgatgtt tacatcattt gcatatcaat ttatactagc atggataatg
    26041 gcttttatag ttaaaagcat aggtggagta ctatttatgg gtaattcaat aatggaagct
    26101 ttgataggtg gaataattat agtccttgca ctctttattc tgtttaataa attcaagtct
    26161 acaaaaaacg gaaatgtctg tagtggatgt tctatttgct ctggatgtcc aagtgctaat
    26221 tcttgctcaa gtaaggaaga cagcaataaa aaaagtaata cacactaata tataaatatt
    26281 ttagtttaaa ataagataaa agtgggtgtc tcaaaattaa ctttttagtt catgaggcac
    26341 tcttttttat ataaaatcaa atatattttc atcatttcaa cagtcaaaaa gaggcttatc
    26401 tctattttga gacaacctct ttttttgtta cttattcagt ttcttgctac ctaacttcat
    26461 gtggaaccta gtatcttttg gaacacttgg gtctacgcct cttaatgtag gtatttcccc
    26521 acatattagt tgtataggta ctataaaatt aaatgtttga tagtaaggat tatctgtgat
    26581 atcaatcttt aaatttttat cattttctgt aacatctcta cctatagcaa atacattttc
    26641 cgtccaacca gaaagtacat caatcatctt agttactcta ggttcttttc ctgtatctag
    26701 tataaatata gtagaatcac tatttatagc attatatata ccgtgtataa actcttcaaa
    26761 ctcataccca gttacaggta ttctcattgt ttccaataat tttaatgctg cttctaatgt
    26821 atctccatat atatcagagt gacctattat tcttatttct ttagaattaa ctaacttttc
    26881 tttgtttctt tcaatccatt gtttagagag cttatacact gcttcaaatc tattaattgc
    26941 atctaatatc ttatttattt cctcattgta cttttcacta gatattgtac ctttttctct
    27001 agctatttga agacctaata acattaagtt taactttgta caataatatc cttttgtttt
    27061 agctccagat ttttcttcac cacaatttac tgttaatata taatcagaaa tctcatctat
    27121 taaagcattc ttacaacctg ccatagatgc tattttacaa cccttatctt cagctaactt
    27181 catagcgttg tatgtagaat aactactccc accttgagat acacctacta ctagggtatt
    27241 ttcattatca aacttgaatg tatcttcagt tatcataaat ggatacattt tcacaacatc
    27301 tatatctaat aaattttgta aatatggttg cacttgcact cctgagtgat agctagtacc
    27361 tgaacctgtt attataatct tttttagatt tgctctctta acttcattaa ataagctatc
    27421 tgcattagat ataatttctc tcattctaac tggtgtttct aacatataat cttgtattgt
    27481 cattttatac accttcctta tctatatatt caataaatta taattaattt ctataacaaa
    27541 cctatagcat gtaaagcgat tcctgttact atagtgccta tagttaattt tgttacactt
    27601 acctttctct tcaacatgta atatattaaa aatgcaaagg ttaaaggtaa catattaggt
    27661 attattttat ctagtatatc ttgtaaaatt acttctgcac catttaagtt aaatttcaaa
    27721 ggagtagtta tactcaacat agttgcaacc attcctccta caacgaataa accgacagtt
    27781 gtagccatag acattatctt ctccataagt ccctctcttt gtattctttc aagagaattt
    27841 acccctactt tataaccata cttaagtcca aatattctaa gggcaaatgc tggtatattg
    27901 tataataata agaataatag tggtccaaag atattgcctt cttttgcaag tgatactcct
    27961 actcctgctg ctataatcct aaatgttccc cagaataatg aatcaccaat tcctgcaaga
    28021 ggtcccataa gagctgtttt aacagcacta attgaacttt catcaaattc tggattatta
    28081 gcattttctt cttccatagc tgctgttata cctaatatag caggaactac cactgtcgtt
    28141 gtattaaaaa tctctaaatg cctttctatt gcttttgctt gattttcttt cttattatat
    28201 agcttcttta ttgcaggtaa cattgaataa caataaccta agttttgcat tctttcgtaa
    28261 ttaaatgcac cttgaagagc aaatgaacgc caaaacatac ttcttaattc tttttttgtt
    28321 aatttattca aagtcaatct ctccttccgt taaagtattc attgctaatt gaggattttg
    28381 attattttct ttgttattga tataaaagtt tagtacaaat gctacacata ctccaaataa
    28441 agctatagca gttatatcta atccaccata agatgctaac aaaaacccta taaagaaaaa
    28501 tacagacatc ttttttgaaa tcaacatatc cataagcaac gcaaaaccta ctgctggcaa
    28561 caatgttcct gcaacaccca atccgtctaa tataacttta ggtattgcat ttatcaatgt
    28621 tgtaacttta tcagcaccaa tcataattgc taaaaaggtt ggaactgatg tacttaaaaa
    28681 gaataatatt actggcaacc acatcattat ggtaactttc ttaaaatcag cctgtttagc
    28741 atagaaaact gccttttgag aaaagtacga atttattatt ctaactaata ctccaagaga
    28801 ttgtgctaat actgctactg gcactgccac tgctaaagca acttctgcac cattacctga
    28861 taatatagca aaagctgtac ccaatacacc tcctgttact acgtctggag gagtagctgc
    28921 acctatccct gcaattccca tccaaattaa ttcaagctgt gcaccaatca taattcctga
    28981 ttttatgtct cctaaaacta atccaactaa catacctgta actattggcc tatcaaacat
    29041 agattgacca aatatacgcc catctagtat accaactcct gctataatag ctaacatagt
    29101 agcttgtact aacatattga acctccattt taacttagtt taatttacat taaattacat
    29161 tacatttttg attttatttc gattttctaa taactcattt acataaacaa ttccattttt
    29221 tgcttcctct aagcctgatt taactattag ttttgtatcc tcctcaacta ataagaatat
    29281 agataaaagc attggtaaat ttacgcctgt caacaattca aatttgaacc cttgcaaaag
    29341 taagtttgta catatatttg ccacacttcc accaaacaca tctgttaaaa caacaaattc
    29401 ttcactatct ttattatttg ataatatact tctaatttct ttctcagcat catctgctga
    29461 tttatctttt gtcatacaaa aatactcaat attagctaat gaaccaatta ttaatttact
    29521 tgtgtcaaca agttctctag acaattctcc atgtgttgca attagaaatt ttttcattct
    29581 ctttctccta aattatttta ttaaatctga tagttgtttc tttttgtctc taggtaacat
    29641 tctaagttct atatcaattc ctaaatcacc tatttcttta aagttattta tatcatcatc
    29701 atcaacagca actaaatctg taagtttctt ttttccttct tcatatctta accctcctac
    29761 atttatttct tttaatactc ctcctgaatt tttagctaca actaaagcat ctctggtatt
    29821 ttttactaac actaatacat tgcttttctt tgaagaagca aatttttcta ctatttctcc
    29881 agattcctct acccccctta tatataaagt tacattgcta ggtttcgcta aattcagtga
    29941 catagctttc atttggtcat tttttgcttc atcatttgca actagtatta catttatacc
    30001 tagtgatgtt gcccatccat atgcaacctg accatgtatc aatctgtcat caattctcat
    30061 caaagatacc attttcccca aatcctccat catacattaa aatttttatt gtttatactc
    30121 tcatttatct ataaaagcaa aaagtatgcc aaatactggc atactatttt aaatttcatt
    30181 tacttatttt gtaatcttgt attttactgt ggtagaccat agataatatt ataaatatat
    30241 cctatctctg aaattggtat ttgcacacta taactctttt ctagcacact aaatgcattt
    30301 tttattagtt ttacttcact atgatggttt ttgattaaca aatccatatc agtatactct
    30361 tcaatttcag tttgtctaac taatctttca atcatacaac ttaaatgaac atataaagaa
    30421 atctttttat catttggaag ttttttcttt tgaatatttt ctatagcatt gattccttct
    30481 tctattctct ctattatctt ttttgaatct aaaatagtta gactgtctat tactctaatt
    30541 aatgaaaaat tctttacaat agaatcattt atgttcttta ttttttcatt ttctactact
    30601 ctactaaata ttctaaaaac atcatcttct ccttttcctg atattatatc ctctaacaat
    30661 ataaaatcca ccccattcac atttggatta gcagttccta ctatagccat cacatcatac
    30721 atttcaaaaa ctggttcttt atctcccata gaaacaagac tatcataatc ataaggtatt
    30781 attttgacat caactatccc aattaaactt tcggaaagta gatgttggat ttttatagca
    30841 gtacctatcc ctgtaaaaca agatgatatt atagcatatt ctttattttt ttgaggataa
    30901 tacaattgta tattaggttt agtttcttca tccataattt ctgcaatctg ttcaatgttt
    30961 ttaccttgca ttaataaatt tcctacttct agtgcagaaa tagtggatat ttggtctata
    31021 aataacattg gcccatttat cttatttttt aaatcttcat agataagatt aagagagccc
    31081 atatcaaata acacaattaa accattcttt atcctatctc cttctaggta tctagacatt
    31141 tgttttgata catcagcaat ggtagcatct ataggcatat caatagctgt aaatatattt
    31201 ttacccaaca tccgattaca tacattcgcc atactactgg cagtagcata tccatgtgct
    31261 ataatagtcg cattaacttg attaaatttc attcttataa ttgttgattt aataaatata
    31321 atcattatga ttgtatctac attattaaga tacatatcca atctattcgt tattaatgtt
    31381 gatattttac ttattataga gtattctttg taactctctt tttttaaata tattagtaat
    31441 ttactttcta aagctttata ctcatcagat aattgataag attcgtcctt caaataaaga
    31501 taagacgaaa atgccaatac attattccca tcgtatttta tattgttatt aacttctaaa
    31561 tttctaaata tatcctgcat tatcgatatt ataagctcca taagtacgtt attattttca
    31621 tcattatttg aaaagactaa attgtccatt agtctaatca ttagattaga actcttttta
    31681 ctaaatattt cttttgttat ttcatttttt tctagtctat caaagtagtc taaacatttt
    31741 atgaaacttt gatagattat atttctttta tttcttccat ttgacatttc aatactaaat
    31801 tgtttaggag aaaagataat gcttttgctt ttaccacttt ggaattgaaa tatatctaca
    31861 ttttctatat aaagatttct agggaggtct tgaagagtaa caaaaatatt tccatttctt
    31921 ctttgatttt ttgcataagc tcgtccacat gcatatttta ttacattttt acattcacct
    31981 atattcccct tgaattttat ctttaaaatc gtatttaatg taatttgagt tatctctata
    32041 ggcaagccaa gtaccttact ttcttcataa ataaaatgtt ctacaatctt tcttttttca
    32101 atagtccctc tttcttctat attgggaaca taaatattta tgggtattct tcttaaaaaa
    32161 gtttgcaaaa atttggatag actttctgtt gttgcaaata ttaatcttac cctagctttt
    32221 ctaattactc cattctctcc aatcctagaa aacgtacctg tatccataaa tgtaaataac
    32281 ttttcctgac cttcactatt taatctatgt acttcatcta aaaataaaac accaccatct
    32341 gattgttcta ttagacctgc tctagattca tttgctccag tatatgctcc ttttacatgc
    32401 ccaaataata gactagacaa taactccaaa ttattataat actgcgcaca gtttaacaca
    32461 ttgtatggag aatttttttc taatacatta ctgcttacac tatatttgta tattatcttg
    32521 gctaaaaaag tttttcctac tccactttca cctgtcagca ttattgtaag tccgccattt
    32581 ggataaagta cagcggtttt tatttgttcg attacttctt ttaagctatt atcatatcct
    32641 atgatactat taaacacagt ctcttgcttt aataatttac actcattttt aagttcatct
    32701 aaattttcat aaatactttt ttttgtaggt cctactacat catttatttt atttttaggt
    32761 aaaaaaataa caggtctact gtttatcttt ataagattat cagattttac taaatcattt
    32821 aataatctac ttgattgagt tctacttaaa ttaaactttt ttactatatc ttctgttatt
    32881 atgccacttt cttttttaag ttcatcaaag ttgttaaata atacacattc atttacaaaa
    32941 cttaaaattt catccctcat gttcaacctc caatacaaat atcaataata ctataatatt
    33001 agtatatcat ttatatattt atgaaaaaga taattatatt cctatcttga ttctcttttg
    33061 taaggttgta aaatcaaact ttttataagt ataaaatcta gattttttaa cataatctca
    33121 aggttcttat ctttccatat atctgacata gaatttatat aagaa
//
LOCUS       DAMJYN010000039        32633 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.040, whole genome shotgun sequence.
ACCESSION   DAMJYN010000039 DAMJYN010000000
VERSION     DAMJYN010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 32633)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32633)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32633
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.040"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(155..994)
                     /locus_tag="PC466_002007"
     CDS             complement(155..994)
                     /locus_tag="PC466_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HDF2769391.1"
                     /translation="MSDIKNEVSKKTLSKKDVIKSWLRWFFFAQSNYNYERLQSTAFS
                     HSMLPVLKKLYPDKEELKQEVETHLAFFNTEPICGCVIHGITIAMEEEKANGADEISG
                     DGMNAIKTGLMGPLAGIGDTLTQGVITPIVLAVCIGLTEGGASIAGPILFVIAQYIIM
                     TSISFGMWTNGYKYGKKAVESILQGGIVNKVIEGASILGTLVMGGLVGRFINLSTPIS
                     YTSGDFKFSLQTDLLDKIFPGLIPLVLTLLVLFALKKGLSPIKIMFILIVVGAITGIL
                     GLF"
     gene            complement(1018..1776)
                     /locus_tag="PC466_002008"
     CDS             complement(1018..1776)
                     /locus_tag="PC466_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF2769392.1"
                     /translation="MHISLIQAVLIAIFYYLSWSPWLTYVGFFTWNRPLLAGFVTGII
                     LGDPVQGAIIGAGINMIYLGFISAGGAQMGDPAFAGYVGTALAIASKLDVSTAMAIAV
                     PLGTVATVLWIGKMTVNSFFAHWADREVQKGNVDRVAFINIVPPQILLFAMSFIPALL
                     VVYFGPNAIDGMLEVMNENVLHVFNVIGAMLPALGIAMNLKLIGNKFTMPFFILGILM
                     AVYFKVDIIVISVIGVILALTITSIKYGKDSATS"
     gene            complement(1823..2296)
                     /locus_tag="PC466_002009"
     CDS             complement(1823..2296)
                     /locus_tag="PC466_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2769393.1"
                     /translation="MSNIALTRIDDRLIHGQVITAWCKITSAKRIVIVDDLVVKDPFI
                     VQVLQMAAPSTVKVEVHDVESGAEVLKSHNGDEHLIVLVKYPKTVLGLVNSGVDLKEL
                     NVGGMGAGLGRKSFYKNISVSDEEKEIFRELISKDVKCFIQIVPDAKKIDVGTLL"
     gene            complement(2325..2741)
                     /locus_tag="PC466_002010"
     CDS             complement(2325..2741)
                     /locus_tag="PC466_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2769394.1"
                     /translation="MIHMTGIIIATHGNMAKAMLESAELIVGKQENVETLGLNHGDSI
                     DEFSRRLEDRIEKYKDEGVLVLLDFYGGTPFNTSAIIINKFAKVCELECLTGVNLPML
                     LELFLNRDTMKLKDLKNLCEEVGISGIKDVKTVLKL"
     gene            complement(2788..3840)
                     /locus_tag="PC466_002011"
     CDS             complement(2788..3840)
                     /locus_tag="PC466_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HDF2769395.1"
                     /translation="MKSVRFYGIRDTRVEDVDVPKILEKDDVIIKVKVAGICGSDISK
                     YSKTGPHMVGEILGHEFSGEVAQVGKEVRSFKIGDRVAVCPAMPCFECDECKKGLYSR
                     CNNVAIIGNKELGGCFAEYTKVKERNLIKIPDEISYETAAALEPVCIAGHGLFRSEAK
                     VGDTVVVLGTGTIGLFSIQWAKIFGSTKIIAVDVFDEKLDLAKELGADICINAKEKNI
                     VEEIKRLTDGDGADIVIESAGTPMTCGQVLLLAKKGGTVLYAGVPYGDVALTREQFEK
                     IVRSELTVKGTWFGNSFPFPGKEWSAGLYHMQKGDMNVEKLVTHRINLEEVPAYFEKV
                     YKRDIFFGKIMINIDN"
     gene            4236..4916
                     /locus_tag="PC466_002012"
     CDS             4236..4916
                     /locus_tag="PC466_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HDF2769396.1"
                     /translation="MKKVYQGKTKDVFELDNGNYLLKFKDDVTGKDGVFDPGENSVGL
                     SIDGIGRANLETSVKFFEILNNAGIKTHYVSANLEEATMEVLPAKVFGNGLEVICRYR
                     AVGSFLRRYGSCVEEGAKLDCYVEATLKDDDRCDPLITSEGLEALNIMTQAQFDSMKS
                     MTQKISNIVRDTIAEKGLELYDIKFEFGFYNDEVILIDEIASGNMRVYKDGVIVDPMD
                     LTALLLDK"
     gene            complement(5049..5369)
                     /gene="sugE"
                     /locus_tag="PC466_002013"
     CDS             complement(5049..5369)
                     /gene="sugE"
                     /locus_tag="PC466_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000118520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quaternary ammonium compound efflux SMR
                     transporter SugE"
                     /protein_id="HDF2769397.1"
                     /translation="MKWLFLFVAGLFEVFWAFQLKNSHGFSKLTPSILTVVGMIVSFY
                     FLSLALKHLPLGTSYAIWTGIGTVGTAIVGMAILNEPISISRIACIGFIVVGIVGLKL
                     LSTN"
     gene            5751..6578
                     /locus_tag="PC466_002014"
     CDS             5751..6578
                     /locus_tag="PC466_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="HDF2769398.1"
                     /translation="MNFYKIAVCQMMTTENKIENINHAVDMVTEAAINGAKIIVLPEM
                     FNCPYENKYFPKFAEEYPGETTTILSKLAEKHGIYLVSGSIPELEYGKIYNTCYVFDK
                     NGALIGKHRKMHLFDIEVTGKVSFKESDTLTAGNDVTVIDTEYGKVGIAICYDIRFPE
                     LSRLMALKGVEIVILPAAFNMTTGPAHWELSIRMRALDNQIFYVGAAPARNMNASYIA
                     FGNSRISDPWGRIIAQADEKECIIYADIDRDLIPDIRQQLPLLKHRRTDLYELNTLK"
     gene            7399..8073
                     /locus_tag="PC466_002015"
     CDS             7399..8073
                     /locus_tag="PC466_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2769399.1"
                     /translation="MNNKILVVDDEEGIITLLKDYFEMNGYEVYTAQSGKDSLKKISK
                     NPDIILLDINMPEIDGIEVCNRIRDYVSCPILFLTARIENTDKINGFRAGADDYIVKP
                     FDLDELGARVSAHLRREQRKSNQTKIKFYNDLTIDYEKRLICIYNNQISLSKKEFDIV
                     ELLSMNPGQVFDKEKIYDRVWGYNSNGNSDVIMEHIRKIRIKLSKHTLENYIETVWGV
                     GYKWIK"
     gene            8061..9221
                     /locus_tag="PC466_002016"
     CDS             8061..9221
                     /locus_tag="PC466_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDF2769400.1"
                     /translation="MDKISNMSLKKAFFVLTLSSLIIASVLTTFAYILLNNLYNSIQD
                     KYLKTPINTGIITIVQNNVNQFSDYDKTLLNIINILQLVLPLIFFIGLLLLADIIFYK
                     VKLKTPIEILNKGAMEISNNNLDFCLEYNNNDELGNLCNAFEKMRSELNKNNINMWTM
                     INDRKQLNAAFSHDLRNPLTVLKGYSNYLTKYIPTGKLSDEKILSTTQLMSEHINRIE
                     YYVENMSNAQRLEDLVVSKSMSNINKFIENLDENISIIAKQEGKSFTLKSQINNINLF
                     FDENIILRVVENIISNAFRYARNNVSILIYLEQELLTFVIEDDGIGFSKESLKLALRP
                     FYRDKTLNDSNPHFGMGLHISKILCEKHGGSISIENNSTNSAKITAKFSTRN"
     gene            9438..9965
                     /locus_tag="PC466_002017"
     CDS             9438..9965
                     /locus_tag="PC466_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014118918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HDF2769401.1"
                     /translation="MKSFANNITFSRIVFALLMLSSTFCSLPFWICYFWCGISDILDG
                     LIARKLRQQSGIGAKLDSIADFIFAVTILVTVGKNIALPMYLWWCIVAIALLRLISYS
                     IGFFKYRTFSSLHTLMNKITGISIFAFPLLYICFGLDVAGIMICIVAFLSSFEEIAIM
                     IKSKELNRDIKSIFM"
     gene            10251..10919
                     /locus_tag="PC466_002018"
     CDS             10251..10919
                     /locus_tag="PC466_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2769402.1"
                     /translation="MIIKAKQLSKIYGSNNNKVIALNNVNLKINSGEFVSVIGPSGSG
                     KSTLLHILSGLDNPTSGQVLLDDKDIYKHTEKELSALRRKSFGFVFQQFNLLPVLTAS
                     ENISMPVLLDKKQPDKDYLNEISSLLGIADRLNHLPHELSGGQQQRVAIARALIAKPD
                     IIFADEPTGNLDSKSGSEVMNLLIKTSKQFGKTLVVITHDDRIAKLADRKISIIDGVL
                     MEVK"
     gene            10922..13390
                     /locus_tag="PC466_002019"
     CDS             10922..13390
                     /locus_tag="PC466_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2769403.1"
                     /translation="MKNYLSLSIKELKSQKLMTTFIIIAIVLSTIMTTVVGQSIGILQ
                     NLRIEQARSFNGDRHVSFHQLTKNQVDDIKKDDRVYQAGTSITIGSSKIKDSGISVLV
                     KEYDKTGLSNYPKLMKLKSGHLPKDKNEIALDENTLKLMGIKPRLGVTIPMNLDISLL
                     NDTIPPYNYTANFKLSGILEDDYTGYVSGIVNGIVGKGTSENLLPKRYILSSLDFKIK
                     QQEKFQEIVNQLAKKINLSHNSIQYNWIYLNALKIQFEKDENSSNSDGISMIILVSLF
                     VALLVLLASGLVIYNILKISVTKKIKEYGCLRAIGAEPNQIYKIVILQILILCTVAIP
                     IGAVIGIISSKGITGMVTNILNPDILLANDNKEITELIHKNTTAYMFPLVLSTNVSLI
                     FSFISALPSAIYASRVSPKIAMAGSTTKIKRKIKREKAIKNFERHLAWLNLKRNKGRT
                     IITILSLFMSITVFVALSEFSNVLDVSRSVSNLKEGDFSLTNEISGFDKSTLDKIDKM
                     KNVNRTSFIKYSEYKQGEIDTDINFENSGEMLKIIGIDEQTLKDLMPSITDSILEDFK
                     NGSICFIKNPIAISTPGVKTRHTNLKPKDSITINKKQLDIYSTVDKMFFLQGNGWING
                     VDVIVYNSVYNTLTNKNKFNQINIYAKDKSKLEQIRLSIEQICENNPGSHWISYIESD
                     KQLKESFKQIEFLAWAVILFVGLIGTLNIINTTHTNINTRTNEIGVKRAIGMSNISLY
                     KMFLWEGVYYGIFAAIFGSIAGYASAIIINMATIEKLDFTNIPITSILQATIISVLAC
                     IIATLIPLRKVKKMNIIDCIDINL"
     gene            complement(13630..15054)
                     /locus_tag="PC466_002020"
     CDS             complement(13630..15054)
                     /locus_tag="PC466_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2769404.1"
                     /translation="MKNQSLITQFRHTFIFIIIASIVATVITYVFALYLYIHSLNKDI
                     YPPNYYERQVPRIEKYINEKNITLLSQSNEEGLKRTIRGDDMPYQVVDNNGNILYGTN
                     PKKLFKTKEELFNNFINKTVRKGGYIHTVPIKGDNGKIEGAVILFYQVKITFANSRGR
                     FVFAVIIMALFSPFIYIVGFTRWLSKRFVKNINQPLHLLIDASKKIKEKDLDFEIDYY
                     SDNELGKLCSAFSEMKDELKGSLSAQWKMEQERVEMVEALAHDLKSPLSIILGYTDAL
                     IGNNTDDNEKLHRYLTVIRENTEKSAALVQKMQYTSDLEKSNIQLNLVPINLPEFLRQ
                     KVQDYELQAHQKEVELILKMKGNIQSPIQIDVDRLTRIFDNIISNSLQYTPSGGNISI
                     TVKDEKNCISYEICDSGRGFSSKDLKKALDKFYRGDEARQTKGGHSGLGLYIVKQLVE
                     QLGGSVKIENSKSGGACVKFWHSI"
     gene            complement(15073..15765)
                     /locus_tag="PC466_002021"
     CDS             complement(15073..15765)
                     /locus_tag="PC466_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2769405.1"
                     /translation="MSKILIIDDEMDLVMLLEDELKAKGHEVLIAYDGQAGIELSKQE
                     PDLIILDIMMPKMNGFEVCQAIRDDVLCPIIFLSAKQSETDKIKGLTFGGDDYVTKPF
                     GLRELMARIEANLRREKRSQYINEENKRSTLYFGKLCLYMKERAIKIDGKNIDLTKIE
                     YDIVELLALHAGQVFSREQIYEKVWGCDSEGDSSTVVERVKKIRAKFSAVTPEKEYIS
                     TVWGIGYKWNKM"
     gene            complement(15820..16596)
                     /locus_tag="PC466_002022"
     CDS             complement(15820..16596)
                     /locus_tag="PC466_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutG family
                     permease subunit"
                     /protein_id="HDF2769406.1"
                     /translation="MIKLLSSEWLRAKRTAVQWLTLCMPIIFSLCVVFYLTTKSGSTQ
                     EFAFEGFFTVWTVFIIPIGVGILAGFIVQEEELAGNFNGFLCVGISRVRLYLGKFLFL
                     LFCLTICTFIATLILCIGMSIAVPSGATIWLFLSAAGLVVIGTLPLLAIHLWVSFAWG
                     MGASIGISIGGILMAAILGLTSVGEKVWAFVPWTWPVKLGMLPGIYFIKEAGTISTEA
                     FYSKVMQTASIELIVVAIGLIIFLIGGVIWFKMWEGRKSY"
     gene            complement(16593..17363)
                     /locus_tag="PC466_002023"
     CDS             complement(16593..17363)
                     /locus_tag="PC466_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutE/EpiE
                     family permease subunit"
                     /protein_id="HDF2769407.1"
                     /translation="MNALQSELLKYKRTFMGKLIVFFPVSFAAYAFIMQSTLMQNPLS
                     QTTSWAWQSLLALIFNWWSFLFLPIGFALFATLVAFQEKKAGNYRALRTHNVSPMTLW
                     INKVIAMAVYSFISTLVLIVVTIITGLILKAGPVPFGQIIGASIVCWVVSLAILPLQL
                     WLATWKGMFLSMGVGALGMIFGVLAATKPFWIAVPWSWAVRMVCPIINIHPNGTILEA
                     GDPLLNTSVIPIGIVVSLVVFIVLTALTAAWFNRRDDK"
     gene            complement(17360..18064)
                     /locus_tag="PC466_002024"
     CDS             complement(17360..18064)
                     /locus_tag="PC466_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic protection ABC transporter
                     ATP-binding protein"
                     /protein_id="HDF2769408.1"
                     /translation="MKDLILETKNLSKRYGEQMAVNNVSLQIERNSIYGLLGPNGAGK
                     STTLKMLVGLLRPTDGRIIFDRKPWKRESLAKIGSLIESPALYGNLTAEENLLVHTKI
                     LGIPKDKIYEVLEIVNLKNTGKKRASQFSMGMKQRLGIAIALLSDPELLILDEPTNGL
                     DPFGIQELRELIASFPKKGITVILSSHILSEVAQVVDNIGIINGGRLLFQGMPDPNEN
                     LEEFFTDVILKGGQNR"
     gene            complement(18319..18831)
                     /locus_tag="PC466_002025"
     CDS             complement(18319..18831)
                     /locus_tag="PC466_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769409.1"
                     /translation="MKKISQEKISTHIQEVPQEKIEQWKSLYEKYKSILKVNSKSVLE
                     IIEFLKRKYVIVEETSEEFKHVVINNIKLNKPFSQKISSDKELKPIVFTIPNEGNAKK
                     LYDTQEETYSGCKIIVGMEFETGCVFVEGSDELNDEITSFKGLDKYDISNYYLVANYI
                     RCLKKYKLID"
     gene            19157..19414
                     /locus_tag="PC466_002026"
     CDS             19157..19414
                     /locus_tag="PC466_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769410.1"
                     /translation="MILNRTELFRGYSLNRFNEICNILSVNKIKYKYKVKNNAYSKKP
                     FSNEITLGNLGQKEDFSYEYLIYVHKDDYEQAESLINSKLR"
     gene            19557..20183
                     /locus_tag="PC466_002027"
     CDS             19557..20183
                     /locus_tag="PC466_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HDF2769411.1"
                     /translation="MKINIKSKLSEFIKQNNLFDDNRIISYLPNITIETDKIKTIMIN
                     EVVPTNTNDDFYSVDKDADYLKTTIPLFDSAGIEVSNINDILDMGIYITNAVKLPKSE
                     YTITRDTIKLHMPILEEEIKLFKNLEVVMLMGDVAKKSFNMITKKHIKKNVIPSISTY
                     KLRNNELYYDNLRVFPSYIMTGGNILIEKSKFEMASEDIKKMFEIING"
     gene            complement(20433..21212)
                     /locus_tag="PC466_002028"
     CDS             complement(20433..21212)
                     /locus_tag="PC466_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901940.1"
                     /note="N-terminal region resembles flavodoxins. C-terminal
                     ferrodoxin region binds two 4Fe-4S clusters; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EFR1 family ferrodoxin"
                     /protein_id="HDF2769412.1"
                     /translation="MNSKIYYFSGTGNSLVVSKILKETLNGSKEVIPLAIHRKENNID
                     INEDILVIVFPVYFADVPDIIKSFVEKLNFNINTHIYAIATCNGVAGHSLFTIDKLLK
                     KRGKKLSAGFLINMPGNALITPSDVEEERLKNQTNRVAEIAKCINNLEIGNIEGKNNL
                     KSHIDSVVLRLVGKNMQIATTKFFAENKCNGCGTCKRVCPVENISIVDKKPKWGNECE
                     RCLACFHWCPKEAINVKKSFLTNRKKYHHPDITVKDIFLDK"
     gene            complement(21280..21741)
                     /locus_tag="PC466_002029"
     CDS             complement(21280..21741)
                     /locus_tag="PC466_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF2769413.1"
                     /translation="MGGAGDYLNGGKMKDFEKLYEATTKLVSTSLKVKDDLKKMFKQN
                     GYDITTDHYALLRFLWEQDGISQIDLCEKSCKDKSNTTRILDVMKNKGLIVRKVDVKD
                     RRKFQIFLTDLGRELEEPLNEIASIYATETFKSISDEELPLFTDILDRIGK"
     gene            complement(21717..22394)
                     /locus_tag="PC466_002030"
     CDS             complement(21717..22394)
                     /locus_tag="PC466_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HDF2769414.1"
                     /translation="MIITVINGSPRKNGATSKVLTYLYKDIERLIPDVKINYFDLSEV
                     NPSYCIGCLNCYKMGKCINQNDKVEYIHDIITKSDGVIFGSPTYGSSVTGLFKVFTDR
                     AHMMLERLLYRKPCIAVTTYENARGSKAISFIKSMVLDSGGYVCGSLSIKTGFNQNPI
                     TEKVESKIQKVSKKFIYCIEEKKNPPVLSQIYNFIAINAVLKPMAFKDIEQYKGIIDR
                     WEEQGII"
     gene            22627..23013
                     /locus_tag="PC466_002031"
     CDS             22627..23013
                     /locus_tag="PC466_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF2769415.1"
                     /translation="MKKLPHISEAEYQVMKIIWKYAPISTTEVIEKLVETSTWSPKTI
                     QTMLLRLVKKGALTYEKNSRVFVYTPLVKEEEYVATESSSFLNRFYNGTLNSMVLNFL
                     ENDKLSEDDIEELREILNKRTTKGDK"
     gene            23016..24815
                     /locus_tag="PC466_002032"
     CDS             23016..24815
                     /locus_tag="PC466_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaR1 family beta-lactam sensor/signal
                     transducer"
                     /protein_id="HDF2769416.1"
                     /translation="MYAPFFIRFLLSTLTLSILIVIILLAKKVFKKHISAKYQYNIGF
                     ILLIMLIIPFVPLKYINLGNVFNYLYTFNQLGSSTNRTSIIKNSPNSIINNSNALNDF
                     SVSLNQVNFDSLNILLLISWIIGILIMIAITIHCNIKIKNMKKSIQILRDEEIVFIFE
                     KCKKDIGINKDFILCKSPIINTPITFGYFKPHIILPDKSISKLSLKDIKYILLHELQH
                     FKNKDILINYIMCFLQILYWFNPLVWYAFKEMRIDREIACDISVLKKLDKDSHIEYGQ
                     TLINFVDNISRPSNLTLTSDIGGSKKQIKKRLLKIMDFHNESNTLKFKSILIFTLIAL
                     IVFGNIPKLSIMADINEKYRPTNEQTVYEDLSQYFKGFDGSFVMYDLKSKQYHIYNKE
                     KSKTRISPNSTYKIYSALLGLENGIITRNNSHIPWDGKHHSNSSWNEDQDLFSAMENS
                     VNWYFQTLDKKTGLKNIQTYLKQIGYGNYDVSGGISNFWLESSLKISPIEQVELLESF
                     YTNKFKFEDKNIETVKDSLLISKKDGVSLFGKTGTANINGKDVNGWFIGYVEKNENTY
                     FFATNIQSKDYSNGSSASKITLSILNDKKIYNP"
     gene            complement(25170..27044)
                     /locus_tag="PC466_002033"
     CDS             complement(25170..27044)
                     /locus_tag="PC466_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF2769417.1"
                     /translation="MNKYNKIANELIEIIGENNIISITHCATRLRVMVKDREIINDKK
                     VEKVNEVKGVFFTSGQYQIILGTGIVNKVYAEVEKMGLKTLSKKEQDELVKNNETGFK
                     KVMRTLADIFVPIIPVIAATGLFLGLKGCLFNDNVLGLFGMSSANIPLYIQTLVSVLT
                     ETAFAFLPAIIVWSAFKVFGGTPVIGLVIGLMLVSPILPNAYSVADPSNEVEAIMAFG
                     FIPIVGCQGSVLTAIVTAFIGANLEKWFRKHMPNVLDLIFTPFFVMLITMLVILLGVG
                     PIMHTIELKMVDIISLLIGLPLGIGGFIIGFTYPLAVITGLHHTYVMIETSLLANTGF
                     NALITLCAMYGFANIGTCLAFMKKSKNNQVKQTAVGAMLSQLFGISEPVLFGIQLRYN
                     LKPLIIMCASSGLGAAILSILHIQSNSYGLAVLPSYLMYIYDGYNLITYLLVSIFVVA
                     FCFIVTCLFGVPKEAINEDEDEELVFNENNENFVSPAKGKIVALENVPDETFSKKMLG
                     DGFAIDIIDGKIVSPISGKLETVFSSGHAFGIKGTNGEVLIHVGIDTVALNGDGFDIA
                     VKQGDMVKQGDVLVNVDLKRIHELGKSTLTMVLFPDGKKVNILDINKDVKIGQRICVE
                     "
     gene            complement(27049..28713)
                     /locus_tag="PC466_002034"
     CDS             complement(27049..28713)
                     /locus_tag="PC466_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HDF2769418.1"
                     /translation="MEKKWWQKEIVYQIYPRSFQDSNNDGIGDLQGIISRLDYLKDLG
                     ITSLWLCPIFKSPMDDNGYDISDYLDIASEFGSMEDLKELIKESKDRGIKIILDLVLN
                     HTSDEHPWFQEALKNPESPYHDYYIFKKGNDLPNNWRSVFGGSVWEKVENRDEYYFHS
                     FGKKQPDLNWENPILRSELYQMINTWSQMGVAGFRVDAITFIKKNLSFQSLESDGVDG
                     LVKCTKTVRNQPGIEKMLYELKENTFKKYDCMTVAEAAGISYDQLGDFIGEDGFFSMV
                     FDFKHADLDVASGSEWFKRISWTIPDLRKCILDSQMYVQEHGWAANFIENHDQPRATT
                     KYLLQYERNDDAVKMLGAMYFFLRGTPFIYQGQELGMTNFKRDTINDFNDLSSIDQYY
                     RSIDEGYSEEEALEFVNLRSRDNARTPFPWADKENAGFSDATPWLKVIENYKDINAQS
                     QINNSESILEFYKKMIKLRQDSKYSDCLIYGSIEPIDIESDNVIAYRRQLDLVVIDCY
                     YNFSDKLVEIKTEEKYDIVFQNLDDINLLNKTVSLKPFQAVLLKVR"
     gene            complement(28727..29548)
                     /locus_tag="PC466_002035"
     CDS             complement(28727..29548)
                     /locus_tag="PC466_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDF2769419.1"
                     /translation="MKLYKLLILDIDGTLRDEVYGIPESAKHAIRLCQKNHCSVVICT
                     GRSIGTIQDDVLSLGVDGYIAGGGNYIQYHGELLYNQSFNQRLIKEVVCLLKKREVAF
                     SIESQEKVFMNQKAKEIFETMNQLKGTNSCINKQHIQEKITYENNIEEYKSQDVHKIC
                     LWSNEKVFDEVKDILQDKMELAQRDISSQYYEIIQKDFHKGKAIKRLQERLGVTQKET
                     ICFGDGQNDIVMFQASDVTIAMKNSHQQLKDIATSICEDIFDNGIYKELKRRNII"
     gene            complement(29647..30411)
                     /locus_tag="PC466_002036"
     CDS             complement(29647..30411)
                     /locus_tag="PC466_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDF2769420.1"
                     /translation="MKIEGLFNKYYNSFTANDKYICECILNHKEDCIKLSIDEFADKY
                     HISTSALSRFAQKLQLPGYSELRVIIRLNETEVEYKNQSKHQLMDCYNKVIDDIEKKD
                     CSIMFERMKKANRIIVFGEGYSQERVVKEMKRIFLPTGKIIYDVYGYDMIQALNHFIK
                     TDDMIFFISLNGDTSTIIDFAKEMRMKGTYMVSITKMISNPLARLCDENLYIQSISIS
                     VDKQLDYDVTTPYFILIELLYIKYKMYLESEHIPRK"
     gene            complement(30408..31157)
                     /locus_tag="PC466_002037"
     CDS             complement(30408..31157)
                     /locus_tag="PC466_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDF2769421.1"
                     /translation="MRLESLVNQSYNSLNENDKIIIKQILICQREYRNFSCEKIANEC
                     NVSRATLLRLCRKIGLDSFSDLKYLLKNNQLEFVNNDNNFHDVCENYRLLMNELQKIS
                     FQDICKIIYDAETIYIYGTGNEQKSLAQEIKRIFLSVGKCVIDLFDIGEIEFMRESFQ
                     KSDLFIIISLSGETKSGIEIAKFINNHIHTISLTRLDNNTIATLCEYNLYVETQKLDT
                     LQAISYEVVGAFYALLDLLHMNYIEYRRRKE"
     gene            complement(31661..32266)
                     /locus_tag="PC466_002038"
     CDS             complement(31661..32266)
                     /locus_tag="PC466_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF2769422.1"
                     /translation="MKIKENVLMLDSTRGSNCFIVFDKEIILIDTGLPFMGKNIIKEL
                     KTLGIKLTDIKHILLTHHDVDHISNIKLLKEKTGAKVWAHVEDIPFIIGEKDRPGFKK
                     FIGKAISRRLIKDVEPYGENMKIGNIKIIHTPGHTPGHVCMIFEDVLFAGDLVKNKNG
                     NIVPYPNPWNWDYKKMMKSIRELDNLKYEWICMSHGTPCIK"
     gene            32445..32543
                     /locus_tag="PC466_002039"
     CDS             32445..32543
                     /locus_tag="PC466_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HDF2769423.1"
                     /translation="MSELSKRDKEKIQRENEIIDKAEKLFCLNGFD"
BASE COUNT        11558 a         5403 c         3941 g        11731 t
ORIGIN      
        1 tattaaatac tatatatagc ttatataagt ttaaaattta atctattata aaattaccct
       61 aattgctaaa ctttttaata taaattttcc aacatcttac aaatataatc aatagatata
      121 gaatcctaat ttacacacca acatatatat ttatttaaaa tagtcccaaa atacctgtaa
      181 tagctcccac tactatcagt ataaacatta tttttattgg agaaaggcct ttttttaaag
      241 caaagagtac taataaagta agtaccaaag gaattaatcc tggaaatatc ttatcaagta
      301 aatccgtttg aagactaaat ttaaaatcac cactagtata acttattggt gtagataaat
      361 taataaacct acctacaagt ccccccatga ctaaagtacc taatatagaa gccccttcta
      421 taaccttatt tactattcca ccttgaagta tactttcaac agcttttttc ccatacttat
      481 atccatttgt ccacattcca aaagaaattg aagtcattat tatatattga gctattacaa
      541 ataatatagg acctgcaatt gatgctcctc cctcagttaa accaatacaa acagctaaca
      601 ctataggagt tataactcct tgagttaaag tatcaccaat tcctgctagt ggacccatca
      661 agcctgtttt gatagcattc ataccatctc cacttatttc atctgctcca ttagcttttt
      721 cttcttccat agctattgtt attccatgta taacacatcc acatataggt tctgtgttaa
      781 aaaatgctaa atgagtctcc acttcttgtt ttaactcttc cttatctgga tataattttt
      841 taagtactgg caacattgaa tgtgagaaag ctgttgattg caatctttca taattgtaat
      901 tagattgcgc aaagaaaaac catcttaacc atgattttat tacatctttt ttgcttaacg
      961 ttttcttaga tacttcattt tttatatctg acataatatt ttccccctca catgtattta
     1021 agatgtagca ctatcttttc cgtacttaat tgaagtaatt gtaagagcaa gtattactcc
     1081 aataacagat attactatta tatctacttt aaaataaaca gccattagta ttcctaatat
     1141 gaaaaagggc atagtaaact tgtttccaat caattttaaa ttcatagcaa tcccaagtgc
     1201 tggcaacata gccccaatta cattaaatac atgtaacaca ttctcattca ttacttccaa
     1261 cataccatct atcgcatttg gaccaaaata aacaactaat aatgctggta taaaactcat
     1321 tgcaaataac agtatctgtg gtggtactat atttataaat gctactctat caacattccc
     1381 tttttgaacc tctctatcag cccaatgtgc aaaaaaagaa tttactgtca tttttccaat
     1441 ccaaagtaca gttgcaacag ttcccaatgg tacagctatt gccattgcag tacttacatc
     1501 tagcttagat gctatagcta aagcagtacc tacatatcct gcaaaagctg ggtcccccat
     1561 ctgagctccc cctgctgata taaaacctag atatatcata tttatacctg ctcctataat
     1621 tgctccttga acagggtctc ctaatataat tcccgttaca aatccagcca atagaggtct
     1681 attccatgta aaaaatccaa cataggtcaa ccacggactc caagaaagat aataaaaaat
     1741 tgctattaat actgcttgaa ttagtgaaat gtgcatattc ttcctcccta ttttctttta
     1801 aagatttaca agatagtctt ttttataata atgttcctac atcaattttc tttgcatctg
     1861 gtactatttg tataaagcat ttaacatctt ttgatattag ttctctaaat atttcttttt
     1921 cttcatctga cacagatata tttttataaa aactttttct accaagccct gctcccatac
     1981 ctccaacatt caattccttt aaatctaccc cactatttac taaacctaag acagttttag
     2041 ggtatttgac caatactatt aaatgttcat ctccattatg tgattttaaa acttcagcac
     2101 ctgattctac atcatgtact tcaaccttaa cagttgatgg agctgccatt tgtaaaactt
     2161 gaactataaa tgggtccttt actactaaat catccacgat tactatcctt tttgccgatg
     2221 taatcttaca ccaagcagta ataacttgcc catgtattaa tctatcatca attcttgtta
     2281 atgctatatt actcataatt attcctccag atttttaatt tattttacaa ctttaaaaca
     2341 gttttaacat ctttgattcc tgatatccca acttcctcac ataaattctt caagtctttt
     2401 aacttcatag tatctctgtt taaaaatagc tctaaaagca taggtaaatt tacacctgtc
     2461 aaacattcta actcacatac cttagcaaat ttatttatta taatagcaga tgtattaaat
     2521 ggagtcccgc cataaaaatc aagcaatact aaaacccctt catccttata tttctcaatt
     2581 ctatcttcta accttctact aaactcatct atgctgtcac catggtttaa tcctaaagtt
     2641 tctacatttt cctgtttgcc tactattaat tcagcacttt ctaacattgc tttagccata
     2701 tttccatgtg tggctataat tatccctgtc atatgaatca tacctttctt aaccttgttt
     2761 atatggatta ttatttagta ctctaatcta attatctata ttaatcatta tcttaccaaa
     2821 gaaaatatcc cttttgtata ctttttcaaa ataagctggt acttcttcta aatttattct
     2881 atgtgttact aatttttcaa cattcatatc acccttttgc atatgataca atccagcact
     2941 ccattctttt cctgggaatg gaaaagagtt tccaaaccaa gttcccttga cagttaattc
     3001 acttcttact atcttttcaa attgttctct agtcaaagct acatccccat atggtacacc
     3061 tgcatacaat actgtccctc cctttttagc taacaacaat acttgcccac atgtcattgg
     3121 agtcccagcc gattcaataa caatatctgc accatctcca tcagttaacc tttttatttc
     3181 ttctacaata ttcttttctt ttgcatttat acaaatatct gcccctaact ctttcgccaa
     3241 gtctaacttc tcatcaaata catctacagc tattattttt gtagagccaa atatctttgc
     3301 ccattgtatt gaaaataatc ctattgtacc tgtaccaagt actacaacag tatctccaac
     3361 tttagcttct gatctaaaaa gaccatgccc tgctatacat actggttcta gcgcagcggc
     3421 agtctcataa cttatctcat ctggtatttt tattaaattc ctctctttca cctttgtata
     3481 ctctgcaaaa caacctccaa gttctttatt tcctattatt gctacattat tacatcttga
     3541 atacaatcct tttttacatt catcacattc aaaacatggc atagctggac aaacagcaac
     3601 tctatctcct attttaaaac tccttacttc tttaccaacc tgtgccactt ctccagaaaa
     3661 ttcatgccct aaaatttctc caaccatatg tggacctgtc tttgaatatt ttgatatatc
     3721 agaaccacat attccagcta cttttacttt aattattaca tcatcttttt ctaatatttt
     3781 tggtacatcc acatcctcca ctcttgtgtc tcttatacca tagaatctaa ctgacttcac
     3841 tattaaccac ccctactttt tatttgagaa tatatcccta ttgtttatat gttaaatatc
     3901 taaagcaact ttcatgccaa tatatgtaag cattgcattc atgcatttta taaaattatc
     3961 attaaatgtg tgtcaaagtg tgtcaaaagt ttcttatatt aaaacttatg tgtgtcaata
     4021 taaacgacac taacatttta tattagttct cttattataa gttttataaa atgtactttt
     4081 tttgttattt ttataaaatt gttcggaaat ttcccttcta tttgtgatat aatattaaat
     4141 ataaggtatc aatataaatt ttcatgcgaa tatcagaact tttttgacac taatgcctta
     4201 ttcaatataa taatttaact ttttggaggt tgtttatgaa aaaagtgtat caaggaaaga
     4261 ctaaagatgt ttttgaatta gataatggaa attacttact taaatttaaa gacgatgtaa
     4321 ctggtaaaga tggagtattt gacccaggcg aaaatagtgt aggtctaagt atagatggaa
     4381 ttggtagagc taatttagag acatctgtta agttctttga aattctaaac aatgctggaa
     4441 ttaaaactca ttatgtaagt gctaatttag aagaagcaac tatggaagtt ctaccagcaa
     4501 aagtttttgg taatggatta gaagttattt gtcgttatag agctgttggt agtttcttac
     4561 gtcgttatgg ttcatgtgtt gaagaaggtg ctaaactaga ttgctatgta gaagcaactt
     4621 taaaagatga tgaccgttgt gaccctctta taacatctga aggtttagaa gctttaaaca
     4681 ttatgactca agctcaattt gattcaatga aaagcatgac tcaaaaaatt tctaatatag
     4741 ttcgtgatac tatagctgaa aaaggtcttg aactttatga tatcaaattt gaatttggat
     4801 tctacaatga tgaagtaatc ttaatagatg aaatagcatc tggaaatatg cgtgtttata
     4861 aagatggtgt aatagttgac cctatggatt taactgctct tttattagat aaatagtata
     4921 tacatataat tttcaaatat aataaactta taaataagat aagctatgaa gtaaagactt
     4981 tttaaatgtt gattattttt aaacattttc tcgcctttaa tttcatagct tatttaaatt
     5041 aatatactct aattagtaga taatagcttt aaccctacaa ttcccaccac aataaagcct
     5101 atacatgcaa ttcttgatat actaataggc tcatttaaga tagccatgcc tacaatagct
     5161 gtaccgacgg taccaattcc agtccatatt gcatatgaag ttccaagtgg aagatgtttt
     5221 agtgctaatg acaaaaaata aaaacttaca atcattccaa caacagtaag tatacttgga
     5281 gttaatttag aaaatccatg tgaatttttt agttgaaaag cccaaaacac ttcaaacaaa
     5341 cctgcaacaa acaaaaataa ccatttcata aactcatccc tcttttcaaa tgtatctctt
     5401 atttttccaa taaaataacc tgagaaatat tataaaatat ctcccaggtt tttgtccttc
     5461 cgtgttcaca acaaaaacta tgttgtgggt tttatctcgg accaggccaa tcattaataa
     5521 ttgcaaaacc ctataaaact ctattaatta ttctatttta tctataataa tactatcaac
     5581 atatataaaa aaagtcaata tatgggttcc atctataata aaaataactt ttatatacct
     5641 tttaatattc ttattcactt ctctccatac ccatttaggt caatctaaga atatctaatt
     5701 tttatttaat atgttataat aacataaaaa tattgaaagg agtaatttct atgaatttct
     5761 ataaaattgc agtatgtcag atgatgacca cagaaaataa aattgaaaat atcaatcatg
     5821 ctgtagatat ggtaacagaa gctgccatca atggagctaa aattatagtt ttgccagaaa
     5881 tgtttaactg cccatatgaa aataaatatt ttcctaaatt tgctgaagaa tatccaggtg
     5941 aaacaacaac gatattgagt aaattagctg agaaacatgg aatttatcta gtttctggta
     6001 gtattcctga gttagaatat ggaaaaatct ataatacttg ctatgtattt gataaaaatg
     6061 gagctctaat tggaaaacat cgtaaaatgc acttatttga cattgaagtt acaggaaaag
     6121 ttagttttaa agaatcagat actcttacag ctggaaatga tgtcactgta atagataccg
     6181 aatatggaaa agttggtata gctatttgct atgatattcg tttccctgag ttatcacgtt
     6241 taatggctct taaaggtgtt gaaatcgtta tcttacctgc tgcatttaat atgactactg
     6301 gtcccgccca ttgggagtta tctataagaa tgcgtgcttt agataatcag atattctatg
     6361 ttggtgctgc acctgctaga aatatgaatg cttcttatat agcttttgga aattcaagaa
     6421 tttcagaccc ttggggaaga ataattgctc aagctgatga aaaagaatgt attatttatg
     6481 ctgacattga tagagattta attcctgaca taagacaaca gttaccactt cttaagcaca
     6541 gaagaactga tttatatgaa cttaatactt tgaaataaaa cagaacataa ccccataaat
     6601 cataaattaa gtgttaaaaa aatttatggg gttctcatta atttgattta aaattaattt
     6661 aataaaaata atgctaaaat taatttaatt aaataatact aataattact aatgattatg
     6721 ctaattgtca gcatttacta atttaatcac tattagttat ttcttttatt aaatatcttt
     6781 acttttttta cttattatgt cttctagctt tacatgtgga ttatggtatt tctttctatt
     6841 tttagtcaca tctttctatt gaattgcttg cttaaaacac caatgcacac atgccagata
     6901 atgttcacaa ttatgtaaaa atattgctct accttcttca atgttgatat tatctctcct
     6961 agttaatatt atctttccta aaatttcttt taattaaaaa acaacattag ttgatatatc
     7021 aagtatattt taagcaactg aaaaaataat aataattgat atatcaacta attaatgtag
     7081 attaattcat ttttataatt tatatacttt ttaattaatc taccttttta attaaaatcc
     7141 ttcctttcta tttatccatt ttcaacttaa attataagat ttcatcagct gtgtttttgc
     7201 attccaataa atattaaata tcaaatatat attctattaa aatttctaat aatttcatcc
     7261 ttgatttatt taatatataa aaatatacta actttaatga ttaagttttg aaatataact
     7321 aagaatttga gaatttattg agatttttat actaaaatat aaatactata caaacttaat
     7381 ttagaaggga gcattcttat gaacaataaa atactcgtcg tagatgatga ggaaggtata
     7441 ataacactct taaaagatta ctttgaaatg aatggttatg aggtttacac tgctcaaagt
     7501 ggaaaagact cattaaaaaa aatatccaaa aatccagata tcattctact tgatataaac
     7561 atgcctgaaa tagatggaat tgaagtttgt aatagaatta gagattatgt atcatgccct
     7621 attctatttc ttacagccag aattgaaaat actgacaaga taaatggttt tcgtgctggt
     7681 gctgatgatt atattgtaaa accttttgat ttagacgaac ttggagctag agtatctgca
     7741 catttaagac gtgaacaaag gaagtcaaat caaactaaaa ttaaatttta taatgattta
     7801 acaatagatt acgaaaaaag gttaatttgt atatataata atcagatttc actttcaaaa
     7861 aaggaatttg atatagtaga gcttctctct atgaatcctg gacaggtatt tgataaagaa
     7921 aaaatatatg atagagtctg gggatacaat agcaatggaa atagtgatgt tataatggaa
     7981 cacattagaa aaatacgaat caaactatca aaacatactc ttgaaaatta tatagaaaca
     8041 gtctggggag ttggttataa atggataaaa taagtaatat gtcattaaaa aaagctttct
     8101 ttgttcttac tttatcttca ctaattatag catcagtact tactactttc gcatacattt
     8161 tacttaataa tctatataat tctatacaag ataagtattt aaaaacacct ataaatacag
     8221 gtattataac catagttcaa aacaatgtga accaatttag tgattatgat aaaacattac
     8281 ttaatataat caacatactt cagcttgtac ttccacttat attttttata ggacttttat
     8341 tattagctga tataattttt tacaaggtaa aattaaaaac acccatagaa atcctcaata
     8401 aaggtgcaat ggaaatatcc aacaacaatt tagatttttg cttagaatat aataataatg
     8461 atgaattagg taatctatgt aatgcttttg aaaaaatgag gtctgaacta aataaaaaca
     8521 acataaatat gtggactatg attaatgata gaaaacaact taatgctgct ttttctcatg
     8581 atttaagaaa tcccctaaca gttctaaaag gttactcaaa ctatttaaca aaatacatac
     8641 caacaggcaa acttagtgat gagaagattt tatcaaccac acaacttatg tctgagcata
     8701 ttaacagaat tgaatactat gtagaaaata tgagtaatgc tcaacgatta gaagatttag
     8761 ttgtttcaaa atctatgtcg aatataaaca agtttataga aaacttagat gaaaatatat
     8821 ctatcattgc taaacaagaa ggaaaatctt ttacacttaa aagtcaaata aataatataa
     8881 atctattttt tgatgaaaat atcattctta gagtcgtcga aaatataata tcgaatgctt
     8941 ttagatatgc tagaaataat gtatccatac ttatatatct tgaacaagaa ctccttacct
     9001 ttgtaattga agatgatggt ataggattta gtaaggaatc tctaaaatta gctttaagac
     9061 ctttctatag agataagact ttaaatgaca gcaatccaca ctttggtatg ggtcttcata
     9121 tctcaaaaat attatgtgaa aaacatggtg gctctatttc tattgaaaat aattctacta
     9181 acagtgctaa aattactgct aaattctcaa caagaaatta aaatgatttt gtaagctttc
     9241 attgttctta tataagcttt gttagtttag aatttataaa atgtatttca atttacaacc
     9301 aatatatata ctattttgta gaagttgtaa gagttgcttc aattataata ttttggcaaa
     9361 aggcatttga aacaataata gaaatatata tttaaatatg tagaatagta tgaaactaga
     9421 attttggagg tgattatatt aaaagttttg ctaataatat tacattctct cgtattgtgt
     9481 ttgcattgct aatgcttagt tctacattct gttcactgcc tttctggata tgttattttt
     9541 ggtgtggaat tagtgatata cttgatggtc ttattgcccg aaagttgaga caacaaagtg
     9601 gaataggtgc aaagttagat agtattgctg atttcatttt tgcggttaca attttggtta
     9661 ctgtcggaaa aaatattgct cttcccatgt atctatggtg gtgtattgtt gcaatagcat
     9721 tattacggtt gattagttac agtattggtt tttttaagta tcgcacattt tcatcgcttc
     9781 atactttgat gaataaaatc actggaattt ctatctttgc ttttccatta ctctatattt
     9841 gctttggtct tgatgttgca ggaattatga tatgtatcgt ggcttttctt tcttcttttg
     9901 aagaaatagc aattatgata aaatcaaaag aattaaatcg tgatataaaa agtatattta
     9961 tgtgacaact tagaatttgt gacaaaaata atttatataa taatgaggaa gtaaaacata
    10021 aaaaattatc cacaagttta tgtgtaaaat agttttaaag caatagagtt gtattgtaaa
    10081 gcctttagtg cataaattac attttaaatt aaaaatgata ctgaaactgc ttatcagcac
    10141 tgcgaattat ccgtaaatag tgaagacttt ttagatttaa gctaaaagtt gggaaaaaat
    10201 tgagttttaa aacttacact cttcttatat agaaaaggag agtgtttttt atgattataa
    10261 aagcaaaaca attatcaaaa atatatggtt ctaataacaa taaagttata gcacttaata
    10321 atgtaaattt aaaaataaac tcaggtgaat ttgtttctgt aattggacct tctggaagtg
    10381 gaaaaagcac acttttacat attttaagtg gattagataa tcctacctct ggacaagtgt
    10441 tacttgatga taaagatata tataaacaca ctgaaaaaga actatctgca cttagaagaa
    10501 aatcctttgg attcgtcttt caacaattta atcttttacc tgttcttaca gcatctgaaa
    10561 atatttcaat gcctgtactt ctagataaaa aacaacctga taaagactat ttaaatgaaa
    10621 tttcatcatt acttggaatt gcagatagac tcaatcatct tccccatgaa ctttcaggcg
    10681 gtcagcaaca aagagttgca atcgctagag cacttattgc aaaaccagat ataatatttg
    10741 ctgatgagcc tacaggaaac ttggacagta aaagtggcag tgaagttatg aatcttctta
    10801 taaaaacttc aaaacagttt ggaaagactt tagtggtaat tactcatgat gatagaattg
    10861 caaaacttgc tgatagaaaa atttcaatta ttgatggtgt tcttatggag gtgaaataga
    10921 aatgaagaat tacctttcac tttcaataaa agaattaaaa agccagaaac ttatgactac
    10981 attcatcatt atagcaatag tactatcaac tattatgaca actgtggttg gacagtcaat
    11041 tggtatccta caaaatttaa gaattgaaca agcccgttct tttaatggtg atagacatgt
    11101 atcctttcac caacttacta aaaatcaagt tgatgacata aagaaagatg atagagttta
    11161 tcaagctggt acttcaataa ctattggcag tagtaaaata aaggattctg gtatctctgt
    11221 acttgtaaaa gagtatgata aaacaggact ttctaactac ccaaaattaa tgaaattaaa
    11281 atctggacat ttgcctaaag ataaaaacga aatagcctta gatgaaaaca ctctaaagct
    11341 tatgggtata aaaccaagac taggagtgac tatacctatg aatttagata tttcactttt
    11401 aaatgatacc ataccaccat ataattacac agctaacttt aaattgagtg gcattttaga
    11461 ggatgattat acaggatatg taagtggtat agtaaatggt attgtaggta aaggtacatc
    11521 agaaaatcta ttacctaaga gatatatttt atcctctttg gattttaaaa taaaacagca
    11581 agaaaagttt caagaaatag taaatcaatt agctaaaaaa ataaatcttt ctcacaattc
    11641 aattcaatat aattggattt acttaaatgc tcttaagata cagtttgaaa aagatgaaaa
    11701 tagttctaat agtgatggta tatctatgat tatattggta tctttatttg ttgccttatt
    11761 ggttttactg gcttctggac ttgtaatcta taatatttta aaaatctctg ttacaaagaa
    11821 aattaaagag tatggatgtt taagagcaat aggagctgaa ccaaaccaga tatataagat
    11881 agttatttta caaatcttaa ttttatgtac tgttgccata cctattggag ctgtaattgg
    11941 aattatctct tctaaaggca taactggaat ggtcactaat atcttaaatc cagatatact
    12001 tctagcaaat gataataaag aaattactga gcttatacat aaaaatacaa cagcatatat
    12061 gttcccatta gtattaagca ctaatgtatc tttgattttt tcatttattt cagcattacc
    12121 atcagcaata tatgcttcac gtgtctctcc caaaattgct atggctggta gtactaccaa
    12181 aatcaaaaga aaaattaaaa gagaaaaagc aataaaaaac tttgaaagac atctagcatg
    12241 gctaaactta aaaagaaata aaggaagaac tataataact atactatcat tatttatgag
    12301 tataacagta ttcgttgcat tgagtgagtt ctctaatgta ttagatgtat ctaggtcagt
    12361 aagcaattta aaagaaggag atttttcctt aacaaatgaa atatctggtt ttgataaatc
    12421 aacactagat aaaatagata aaatgaaaaa cgtcaatcgc acttccttta taaagtactc
    12481 tgaatacaaa cagggtgaaa tagatacaga tataaatttt gaaaatagtg gtgagatgtt
    12541 aaaaatcatt ggaattgacg agcagacttt aaaagactta atgccttcta ttacagattc
    12601 tatactagaa gactttaaaa atggttctat ctgttttata aaaaatccga ttgctatttc
    12661 tacaccaggt gtaaaaacta gacatacaaa tttaaaacct aaagatagta tcacaatcaa
    12721 caaaaaacaa ctagatatat atagtacagt agataaaatg ttctttttac aaggtaatgg
    12781 ctggataaat ggtgttgatg ttattgtata taattctgtt tataacacct tgacaaataa
    12841 aaacaagttc aaccagataa atatttatgc taaagataaa tcaaaattag aacaaataag
    12901 attgtctatt gaacagattt gtgaaaataa tcctggctct cattggatat catatattga
    12961 atcagataag caacttaaag agagttttaa acaaatagaa tttctagcat gggcagttat
    13021 attatttgtg ggattgattg gtactttaaa catcattaac acaactcata caaatataaa
    13081 tactaggact aatgagattg gagttaaaag agctattggt atgagtaata ttagcttata
    13141 taaaatgttt ttatgggaag gtgtttatta tggaattttt gctgctatat ttggttcaat
    13201 tgctgggtat gccagtgcta ttattataaa catggcaact atagaaaagc ttgatttcac
    13261 taatatacca attacttcaa ttttacaagc tactattatt tctgtacttg catgtattat
    13321 agctactctt attccgttaa gaaaagttaa aaagatgaat ataattgact gtatagatat
    13381 caatttataa ctattttaca gataataata taaattaaat tatcaatgac tgtctctatt
    13441 ttctttcaaa tctaactaat aaatcttttt aactataata taagctttaa aaaaggcctg
    13501 tctcaaaata gagataagcc ttttttcatt gtcggaataa tgaaaatata tttaacttca
    13561 caaaaaaaga gtgcctcacg aattaaaaat ttcgctttga gacactcccc tttaatttaa
    13621 aatatatagt taaatgctat gccaaaattt cacacatgct ccacctgatt ttgaattttc
    13681 tattttaaca gaacctccaa gctgttccac taattgtttg acaatgtaaa gcccaagacc
    13741 agaatgtcca ccttttgtct gcctagcttc atctcctcga taaaacttat caagagcctt
    13801 ttttaaatct ttagagctaa accctctacc agaatcacaa atctcataag aaatacaatt
    13861 tttttcatcc tttacagtaa tactaatatt accacctgat ggagtgtatt gcagactgtt
    13921 ggatatgata ttatcaaaaa ttcgtgtcaa cctatccacg tcgatttgaa ttggggattg
    13981 tatattcccc ttcattttca atataagttc aacttccttt tgatgagcct gtaattcata
    14041 gtcttgcacc ttttgcctca aaaattcagg taaatttata ggaacaagat ttaattgtat
    14101 atttgacttt tctaagtcag acgtatattg catcttttgg acaagagcag cacttttttc
    14161 tgtattttct cttatcactg taagatacct atgaagtttt tcattgtcat ctgtattatt
    14221 accaataagt gcatctgtat atcccaaaat aatagaaaga ggagatttta aatcatgtgc
    14281 tagagcttcc accatttcaa cacgttcctg ctccatcttc cactgcgcag ataaagaacc
    14341 ttttaattcg tctttcattt cagaaaaggc actacaaagt ttaccgagtt cattatctga
    14401 ataatagtcg atttcaaaat caaggtcctt ttcttttatc ttcttggacg catcaatcaa
    14461 tagatgtaat ggttgattga tattctttac aaagcgctta gaaagccatc tagtaaaacc
    14521 cacgatatat ataaatggag aaaacagagc cattataata actgcaaata caaatctccc
    14581 tctactattt gcaaaggtta ttttgacttg atagaataga ataacagctc cctcaatctt
    14641 tccattatcc cctttgattg gaacagtatg gatataacca cctttacgaa cagttttatt
    14701 gataaaatta ttaaataatt cttcttttgt tttaaatagt tttttggggt tagtaccata
    14761 tagaatattg ccattattat ccacaacttg atatggcata tcatccccac gaatcgttct
    14821 ttttaaacct tcttcattcg attgtgataa caaagttatg tttttttcat tgatgtattt
    14881 ttcaattcta ggaacttgtc gctcataata gtttggtgga tagatatcct tatttaagga
    14941 atgaatatac aaatagagag caaatacata agtaatcact gtggcaacta tactggctat
    15001 tataataaaa ataaaagtat gtctaaattg ggtaataagg gattgatttt tcatttaata
    15061 acctctctct ctttacattt tattccactt atacccaata ccccaaactg tggaaatata
    15121 ttctttttct ggtgtcacag cagaaaactt agctcgtatt ttttttactc gttcaacaac
    15181 agttgaggaa tcaccttcag aatcacaccc ccatactttt tcatagattt gttctcttga
    15241 gaaaacttgt cctgcatgga gtgctagtaa ttcaacaata tcatactcta tttttgttaa
    15301 atcaatattc ttaccatcaa ttttaattgc acgttccttc atatataagc ataacttccc
    15361 aaaatacaaa gtagatctct tgttctcttc attgatatac tgtgaacgct tttccctacg
    15421 cagattagct tcaatccttg ccataagttc acgcagtcca aatggctttg ttacataatc
    15481 atcccctcca aaggtcaacc ctttgatttt gtcggtttct gattgctttg cacttaaaaa
    15541 tataattggg cataaaacat catctctaat tgcctgacat acctcaaatc cattcatttt
    15601 aggcatcata atatccagta taataaggtc aggctcctgt tttgataact ctatacctgc
    15661 ctgaccatca taagctatca acacttcatg tccttttgcc ttcaattcat cctcaagtag
    15721 cattactagg tccatttcat catcaataat caatatttta ctcaatataa caccaccttt
    15781 ctcttatggg aaggtcagta ttaaaacaat attcgtctac taataacttt tccttccctc
    15841 ccacatttta aaccaaataa cgcctcctat caagaatata atcaaaccta ttgctactac
    15901 tataagctct atactagctg tttgcatcac tttagagtaa aatgcctcag ttgaaatagt
    15961 tccagcttct ttaataaaat aaattcctgg aagcatacct agttttactg gccatgtcca
    16021 tggaacaaat gcccatactt tttcaccaac gctagttaat ccaagtattg ctgccatcaa
    16081 aattccaccg atactaatac caatagatgc acccataccc catgcaaaac tcacccaaag
    16141 atgaatagct aatagtggaa gtgtcccaat caccacaagt cctgctgctg acaggaataa
    16201 ccatattgtt gctccagatg gcactgcaat actcattcct atgcaaagta tcaacgtagc
    16261 aataaatgtg catatagtta ggcaaaacag aagaaaaaga aattttccca gatataatct
    16321 aacacgagaa atacctacac ataaaaaacc attaaaattt ccagcaagct cttcctcctg
    16381 cactataaat cctgctaaaa tacctactcc aataggaatg atgaatacag tccatactgt
    16441 aaaaaatcct tcaaaagcaa attcttgtgt acttccagat ttagttgtga gataaaaaac
    16501 cacacataat gaaaaaataa taggcataca aagagtaagc cactggacag ctgtcctctt
    16561 tgctcgaagc cattctgatg ataatagctt tatcatttgt catccctcct attgaaccaa
    16621 gctgcagtaa gcgctgttaa tactataaac acaaccaaag aaacaacaat cccaatagga
    16681 atcactgaag tattcaaaag tgggtctcca gcttctaata tagtaccgtt aggatgtatg
    16741 ttgatgattg ggcataccat tctaactgcc caactccaag gtactgcaat ccaaaatggt
    16801 tttgtcgcag caaggacacc aaatatcata cctaaagctc caactcccat acttaggaac
    16861 atacctttcc atgtagctag ccatagctga agtggaagta tagcaagaga aacaacccag
    16921 catacaatac ttgcccctat aatctgtcca aaaggaactg gaccagcttt caatattaaa
    16981 ccagttataa ttgttacgac tattaaaact aacgttgaaa taaaactgta gactgccata
    17041 gctataactt tattaatcca aagtgtcata ggagacacat tgtgtgtacg taaagcacga
    17101 taatttccag cttttttttc ctggaaagct accaaagtag caaacaatgc aaatccaata
    17161 ggcagaaata aaaatgacca ccagttaaaa attaatgcta aaagactttg ccacgcccaa
    17221 gaagttgttt gagataatgg attttgcatg agtgttgatt gcattataaa tgcatatgct
    17281 gcaaaagaca ctgggaaaaa aacaataagt ttacccataa atgttctttt atactttaaa
    17341 agttctgatt gtaaagcatt catctgtttt gtcctccttt aagaataaca tctgtaaaaa
    17401 attcttctag attttcatta gggtcaggca ttccttgaaa tagtagtcgt cctccattta
    17461 taattcctat attatctaca acttgagcaa cctctgatag aatatggcta gaaagaatta
    17521 cagttatacc tttttttgga aaagaagcaa tcaattcacg caattcttga atgccaaagg
    17581 ggtcaagacc attggttggt tcatctagta ttaacaactc tgggtcactc aaaagtgcaa
    17641 tagctattcc taacctttgt ttcataccca tagaaaattg tgaagctctc tttttacctg
    17701 tatttttcaa atttactatt tccaacactt cataaatttt atctttaggt attcccaata
    17761 tttttgtatg tactaacaaa ttttcctctg ctgtaaggtt tccatacaat gcaggggatt
    17821 ctattaaaga acctattttt gcaagagatt ctcgtttcca aggctttcta tcaaaaataa
    17881 tacgaccatc tgttgggcga agaagaccaa caagcatttt aagtgttgtg gactttcctg
    17941 ctccatttgg tcctaaaagt ccatatatac tatttcgttc aatttgtaga gaaacattgt
    18001 taactgccat ttgttctcca tatctttttg ataagttttt tgtttcaaga attaaatctt
    18061 tcatattaat ttctcccttc ttgtaatacc ttaaatctat tactaagaga atactaacat
    18121 gaaaaaataa caattctata acacctacta attttaataa aaattaaaat aaaaaataga
    18181 gttaccaatt ttattttggc aactctattt aagtttatgt tttacagtta tattagattt
    18241 aagcttagtt tcattatcac actaacttca aatttactct ataatcctta aatcaagcac
    18301 taatttatta atcaaacact aatctattaa tttatatttc tttagacatc taatatagtt
    18361 tgctactaaa taataattac ttatatcata tttatctaat cctttaaaag aagttatttc
    18421 atcattaagc tcatcactac cttctacaaa aacacaacct gtttcaaatt ccatacctac
    18481 aataatctta cagccactat aagtttcctc ttgagtatcg tacaattttt ttgcatttcc
    18541 ttcatttgga attgtaaata caataggttt taattcttta tcactggaaa tcttttgtga
    18601 aaaaggcttg tttaacttaa tattattgat aactacatgt ttaaattcct ctgaagtttc
    18661 ttctactatt acatattttc gctttaaaaa ctctattatt tctaaaacag acttagaatt
    18721 tacttttaaa atacttttat atttttcata taaagatttc cactgttcaa ttttttcctg
    18781 tggtacttct tggatatgtg tacttatttt ttcttgagat atttttttca attaaactct
    18841 cctttcaata cttaaatatc cttataaatc tcacatgact aaagttacaa ggttcctact
    18901 taatagaatt ttgcatactt aaatatgtct tattaattct ctacaggata tctccgtagt
    18961 ccctacgatt cttacataag ttacctattt taaattgtta ttagttagat tataaaaatt
    19021 atttatttta tcactaatat aatactctta aaaactttac aaatcaattt aaatttgcta
    19081 ccttttattt ataacaactt atagtacatt tctcctatgc ttttcaatat attactttta
    19141 aaaggaggtt ttccttatga ttttaaatag aactgagctt ttccgaggat attctttaaa
    19201 tagatttaac gagatatgca atatattatc agtaaataaa attaaatata agtataaagt
    19261 gaaaaataat gcttactcta aaaaaccttt ttctaatgaa ataacacttg gcaatttagg
    19321 tcaaaaggaa gatttctctt atgagtactt aatttatgtt cataaagacg attatgaaca
    19381 ggcagagtct ctaataaatt ctaagttgcg atagattatt tataaaacat gacattctgt
    19441 tgtcatgttt tatatgttat tatactttca aatatgctac tatattttca aaattgtgtg
    19501 ctttaaaact agctttttat agtaatttaa agcttaaaac taaggagact cgttatatga
    19561 aaataaatat aaaatcaaag ttaagtgaat ttattaaaca gaacaatctt tttgatgaca
    19621 acagaataat atcctacctt cctaatataa caatagaaac agacaaaata aaaactataa
    19681 tgattaatga ggttgtccca actaacacca atgacgattt ttatagtgta gataaagatg
    19741 ctgattattt aaaaactact attcctttat ttgacagtgc aggaatagaa gtatctaaca
    19801 taaatgatat cctagatatg ggtatctata taactaatgc agtaaaactt cctaaatcag
    19861 aatatacaat aactcgtgat acaattaaat tacatatgcc tattttagaa gaagaaatta
    19921 aattatttaa aaacctagag gtagtaatgt taatgggaga tgttgcaaaa aaatctttta
    19981 atatgattac taaaaagcat ataaaaaaga atgtcatccc ttccatttca acatataaac
    20041 ttcgtaataa tgaactttat tatgataatt taagagtatt tccatcatat attatgactg
    20101 gtggaaacat actgattgaa aaatcaaaat ttgaaatggc atcagaagat ataaaaaaaa
    20161 tgttcgagat tataaacggt tgatattaca aaataataaa aactaattta gccaaataat
    20221 aagtgcctca aaaacttcta tttatgaggc acttttattt tatattagtg taactatata
    20281 ctattaacat aatttattat ttatattgtt ctttttaatc tctattccat ttagtctagg
    20341 taacattact ctttacaaga ttactttata tttcttttat atctctaacg tttttattta
    20401 ataaaacaat tattaataca agtcaaatat atctatttat ctaaaaatat atcttttaca
    20461 gtaatatctg gatggtgata cttcttccta ttcgttaaaa aagatttttt tacattaata
    20521 gcctcttttg gacaccagtg aaaacaagct aggcatcttt cacactcatt accccacttt
    20581 ggctttttat caactatact tatattctct acaggacaaa cccttttaca tgtcccacat
    20641 ccattacatt tattttctgc aaaaaattta gtagttgcaa tttgcatatt cttacctact
    20701 aaacgaagta caacactatc tatatgtgac tttaaattgt tttttccttc tatatttcca
    20761 atctccaagt tattgataca ttttgcaatc tcagctaccc tattagtctg atttttcaat
    20821 ctttcttctt caacatctga aggtgttatc aaagcatttc caggcatatt gattaaaaaa
    20881 ccagcagata attttttccc ccttttttta agtaacttat ctatagtaaa taaactatgt
    20941 ccagctaccc cattacaagt ggcaatggca tatatatgag tattaatatt aaaatttaat
    21001 ttctctacaa aagactttat tatatcagga acatcagcaa aataaacagg aaaaacaatt
    21061 accaatatat cttcatttat gtctatatta ttttcttttc tatgtatagc taaaggtata
    21121 acttctttac ttccatttaa cgtttctttt aaaatctttg aaactactag cgaatttcct
    21181 gttccagaaa aataataaat cttactattc attcttatcc ctctttctat atttctacat
    21241 catcaatagt taaaaagtct cttaaaatag gatttatatt tactttccaa ttctatccaa
    21301 aatatcagta aacaaaggca attcttcatc agagatagat ttaaatgtct ctgttgcata
    21361 tatacttgca atttcattta atggttcttc taattctcta cctaaatctg ttaggaatat
    21421 ttgaaactta cgtctatctt taacatctac tttacggaca attaatccct tatttttcat
    21481 aacgtctaaa attcttgttg tattagattt atccttacat gatttttcac ataaatctat
    21541 ctgagaaatt ccatcttgct cccatagaaa ccttaataac gcataatggt cagttgttat
    21601 atcatatcca ttttgtttaa acatcttttt taaatcatct tttactttta acgaagtact
    21661 tactaactta gttgtagctt catatagttt ctcaaaatct ttcattttac ctccatttaa
    21721 ataatcccct gctcctccca tctatcaatt attcccttat attgctcaat atctttaaaa
    21781 gccattggct ttaaaacagc atttatagca ataaaattat agatttgaga aagcacaggt
    21841 ggatttttct tttcctctat gcaataaata aattttttag ataccttttg tatctttgat
    21901 tctacttttt cagttatagg attttgatta aatccagttt ttatagataa actaccacaa
    21961 acataacctc ccgaatctaa gaccatggat tttataaaag aaattgcttt tgaaccacgt
    22021 gcattttcat atgtagtaac tgctatacat ggcttacgat acaataatct ttcaagcatc
    22081 atatgtgctc tatctgtaaa caccttgaaa agtccagtta cactacttcc ataagttggg
    22141 ctaccaaata taacaccatc actcttagta attatatcat gaatatactc tactttatca
    22201 ttttgattga tacacttgcc cattttataa caatttaaac aaccaataca atatgatgga
    22261 tttacctcac ttaaatcaaa ataattaatt tttacatctg gtattaatct ttctatatct
    22321 ttatacaagt aagttaaaac ttttgatgta gctccatttt ttctagggct tccatttata
    22381 actgtaatta tcatttctat atctcctttt tagttgttat atcaacaata agtatatcaa
    22441 ctatattttt agctgtcaat ataaaccatt tatttaaagc tatacttaca cagcttaaat
    22501 aaaagtttta tttaactaca tgtgcttatt taatcaacta taaatgaatt atttttaata
    22561 attgacaaac taaattaatg ataatatact ttatgtatta caaatgtaag tagaaggagg
    22621 tatagtatga aaaagttacc acatatttca gaagcagaat atcaagttat gaaaattatt
    22681 tggaaatatg ctcctatcag cactactgaa gtaattgaaa agttggtaga aacaagtaca
    22741 tggagtccta aaacaattca aacaatgtta ttgagattag ttaaaaaagg agctttaaca
    22801 tatgaaaaaa atagcagagt attcgtttat actccacttg ttaaagaaga agaatacgta
    22861 gctacagaaa gtagttcttt tttaaatcgt ttttataatg gtactcttaa ttctatggta
    22921 ctaaactttt tagaaaatga taaactatct gaagatgata ttgaggaact gagagaaatc
    22981 ttaaataaaa ggacgactaa gggggataaa taaatatgta tgccccattc tttatacgat
    23041 ttttactcag tacattaacc ttatcaatat taattgttat aattttactt gccaaaaaag
    23101 tatttaaaaa acatatttct gcaaagtacc aatacaatat tggatttata ttgcttataa
    23161 tgttaataat tccatttgtc cctcttaaat atattaatct tggaaatgta tttaactatt
    23221 tatatacttt taatcaactt ggaagcagta ctaataggac ttctattata aaaaatagtc
    23281 caaattctat aattaataac tcaaatgcat taaacgattt ttcagtatcc ctaaaccaag
    23341 ttaattttga tagtttaaat attttattac taatatcatg gataattgga attttaatca
    23401 tgatagctat tactattcat tgcaatatta aaataaaaaa tatgaaaaaa tcaatacaaa
    23461 ttttaagaga tgaggagata gtatttatat ttgaaaagtg taaaaaagat attggtataa
    23521 ataaggattt tatactatgc aaatcaccta ttataaatac acctattaca tttggatact
    23581 ttaaaccaca cattatatta ccagataagt ctatatctaa attatcttta aaagatataa
    23641 aatatatctt acttcatgaa ttacaacact ttaaaaataa agatatactg ataaattata
    23701 taatgtgctt ccttcaaata ttatattggt ttaatcctct tgtatggtat gcatttaaag
    23761 aaatgcgtat agaccgtgaa attgcatgtg atatttcagt tttaaaaaag cttgataaag
    23821 atagtcatat agaatatgga caaactctaa taaactttgt ggataatatt tcaagaccat
    23881 caaatcttac acttacatca gatattggtg ggtcaaaaaa acaaataaaa aagcgactat
    23941 tgaagataat ggattttcat aatgaatcaa atacgttaaa attcaaaagc attttaattt
    24001 ttacattgat agctttaatt gtatttggaa atattcccaa actatctatt atggcagata
    24061 tcaacgaaaa atatagacct acaaatgaac aaactgtgta cgaggactta agtcagtatt
    24121 ttaaaggttt tgatggaagt tttgttatgt atgatttaaa atccaagcaa tatcatattt
    24181 acaataaaga aaaaagtaaa acaagaattt ctccaaattc tacttataag atttatagtg
    24241 ccttattggg attggaaaat gggataataa caagaaataa ttcacatatc ccttgggatg
    24301 gaaagcatca ttctaatagt tcttggaatg aagaccaaga cttattttct gctatggaaa
    24361 actccgtaaa ctggtacttt cagactctag acaaaaaaac agggctaaaa aacatacaaa
    24421 cttatcttaa gcaaattgga tatggcaatt atgatgtttc aggtggtatc tcaaactttt
    24481 ggctagaatc ttcattaaaa atatcaccta ttgaacaggt agaattactt gaaagttttt
    24541 atacaaataa gtttaaattt gaagataaaa atatagaaac agtaaaagat tcattgttaa
    24601 tatcaaaaaa ggatggggta tcactttttg gtaaaacagg cactgctaat ataaatggaa
    24661 aagatgtaaa tggttggttt ataggttatg tggaaaaaaa tgaaaatact tatttctttg
    24721 ctacaaatat tcaaagcaaa gattattcta atggtagttc agcatctaag ataacattat
    24781 ccatattaaa tgacaaaaaa atctataatc cttaatatat ttactgtaca ttctaaaaaa
    24841 ttcacataat tttcatatta attatcgatt aaattcatat acaaggctta ttatataaac
    24901 atagaagata gtaaaactag cttaaaaaca taatataata ccctatacaa atagtggcaa
    24961 ctctccctca catcctcaat tgttgccact atttaatttt ttgtatgaag ttaaatatat
    25021 tttcatcatt tcaacaattt gggtgcagta caatctctat tttgagacaa cctctttaat
    25081 tgttttagag tttatgaatt atttctcata ctttaaaaag attgaattac tcttgataat
    25141 cttcttttgt agtcattaca tatcacctac tactcaacac atattctttg acctattttt
    25201 acatccttgt ttatatccaa aatatttacc ttcttaccat ctggaaacaa taccattgtc
    25261 aaagtagact ttcctaattc atgtattctc tttaaatcaa cattaacaag aacatctccc
    25321 tgtttaacca tatctccttg tttaacagca atatcaaagc catctccatt taatgcaact
    25381 gtatcaattc caacatgaat taatacttct ccattagttc ctttaatccc aaatgcatgt
    25441 ccacttgaaa atactgtttc taatttacct gaaataggag aaacaatttt tccatctata
    25501 atatcaatag caaaaccatc acctaacatt tttttagaaa atgtttcatc tggtacattt
    25561 tctaatgcaa caattttccc cttagctgga gacacaaagt tttcattatt ttcattaaac
    25621 actaattctt cgtcttcatc ttcatttata gcttctttag gcactccaaa taaacatgtt
    25681 acaataaagc agaatgcaac cacaaatatt gatactaata agtatgtgat taaattatat
    25741 ccatcataga tatacattaa ataagaaggt aaaactgcta atccatatga attagattga
    25801 atatgtaaaa ttgataatat tgctgctcct aaacctgaag atgcacacat aataatcaaa
    25861 ggctttaaat tatatcgaag ctgaatccca aataaaacag gctcacttat accaaaaagt
    25921 tgagatagca ttgctccaac tgcagtttgt ttaacttgat tatttttaga ttttttcata
    25981 aatgctagac atgttccaat attcgcaaat ccatacattg cacaaagagt aataagtgca
    26041 ttaaatcctg tatttgctaa tagtgatgtt tcaatcatta cataagtatg atgtaagcca
    26101 gtaataacag ctaatggata tgtaaatcca ataataaatc ctccaattcc taaaggtaaa
    26161 ccaatcaata aactgatgat atcaaccatt tttaattcta ttgtatgcat tataggccct
    26221 acacctaaca aaataactaa cattgttatt agcataacaa agaatggtgt gaaaataagg
    26281 tctaatacat taggcatatg tttacggaac catttttcaa gattagctcc aataaatgct
    26341 gtaacaatag ctgttaaaac acttccttga cagcctacaa taggaataaa tccaaatgcc
    26401 ataattgctt caacttcatt tgatgggtca gcaacagaat atgcattagg aagtattgga
    26461 gaaactaaca taagtccaat aacaagtcca ataacaggtg ttcctccaaa taccttaaat
    26521 gctgaccata caataattgc tggtaaaaaa gcaaatgctg tttctgtaag aaccgaaaca
    26581 agtgtctgaa tatacaatgg aatatttgca gaagacattc caaataatcc aagtacatta
    26641 tcattaaaca aacaaccctt taatcccaag aataatcctg ttgccgcaat aactggaata
    26701 ataggaacaa atatatctgc tagagttctc ataactttct taaatccagt ttcattattt
    26761 ttaactaatt catcttgttc tttttttgat aaagttttca atcccatttt ttcaacttct
    26821 gcataaactt tattgactat tcccgttcct agaataattt gatactgtcc agaagtaaag
    26881 aaaacacctt taacctcatt aaccttttcc actttcttat cattaataat ttctctatct
    26941 ttaaccatca cccttaatct tgtggcacaa tgtgtaatag aaataatatt attttcacca
    27001 ataatttcaa taagctcatt tgctatttta ttatatttat tcatttttct acctcacttt
    27061 caataatact gcttgaaatg gtttcaaact cactgtttta tttagtagat ttatatcatc
    27121 taaattttgg aatacaatat catatttttc ttctgttttt atttctacaa gtttatcaga
    27181 aaaattataa taacaatcaa taactaccaa atctaattgc cttctatacg caataacatt
    27241 gtcactttct atatcaatag gttctattga accataaatc aaacaatcag aatacttact
    27301 atcttgtctc aactttatca tctttttata aaattctaaa atactttctg aattgttaat
    27361 ctgactctgt gcattaatat ctttataatt ttcaataacc tttaaccatg gtgttgcatc
    27421 tgaaaaacct gcattttctt tatctgccca tggaaatggc gttcttgcat tatctcggct
    27481 tcttaaattc acaaattcta acgcttcttc ttctgagtaa ccttcatcta ttgaacgata
    27541 gtattggtca atgctagata aatcattaaa atcatttatg gtatctcttt taaaatttgt
    27601 cattcctaat tcctgtccct gataaataaa tggtgttcct cttaaaaaga aatacattgc
    27661 tcccaacatt tttactgcat catcattcct ttcgtattgc aaaagatact ttgttgtagc
    27721 tcttggttgg tcatgatttt caataaaatt agctgcccat ccatgttcct gaacatacat
    27781 ttggctatct aaaatgcatt ttcttaaatc tggaattgtc catgaaattc ttttaaacca
    27841 ctcactacca gaagcaacat ctaagtcagc atgtttaaag tcaaagacca ttgaaaagaa
    27901 accatcttct ccaataaaat cacctagttg gtcatagcta atacctgctg cttcagcaac
    27961 agtcatacaa tcatattttt taaacgtatt ttcttttaat tcataaagca ttttttctat
    28021 tccaggctga tttctaactg tttttgtaca tttaacaaga ccatcaacac catcactttc
    28081 taaactttga aaacttaaat tctttttgat aaatgtaata gcatcaactc taaatcctgc
    28141 cactcccatt tgagaccagg tattaatcat ttggtaaagt tcacttctta atattggatt
    28201 ttcccaatta aggtcaggtt gttttttacc aaaagaatga aaataatatt cgtctctatt
    28261 ctctaccttt tcccaaacac ttccaccaaa aacagacctc cagttatttg gtaaatcgtt
    28321 tcctttttta aaaatataat aatcatgata aggactttct ggatttttta atgcttcttg
    28381 aaaccaagga tgttcatcac ttgtatgatt aagaactaaa tctaatataa ttttgattcc
    28441 tctatcttta ctttctttaa ttaactcttt taaatcttcc atacttccaa attcacttgc
    28501 aatatctaaa taatcactaa tatcataccc attatcgtcc ataggtgatt taaaaattgg
    28561 acataaccac aatgatgtaa tacctaaatc ttttaaataa tctaaacgag aaataattcc
    28621 ctgtaaatct ccaattccat cattattact atcttgaaag cttcttggat aaatttgata
    28681 aacgatttct ttttgccacc atttcttttc cataaattac tcctttttat atgatatttc
    28741 ttctttttaa ttctttataa attccattat cgaatatgtc ctcacatata gatgtcgcta
    28801 tatctttaag ttgttgatga ctatttttca ttgcaattgt aacgtctgat gcttgaaaca
    28861 tgacaatatc attttgacca tcaccaaaac atatggtttc tttttgagtt acccctaatc
    28921 tttcttgtaa tctcttaatt gctttgccct tatgaaaatc tttttgaata atttcataat
    28981 actgactaga aatatctctc tgtgctaatt ccattttatc ttgtagtata tctttcactt
    29041 cgtcaaatac cttttcattt gaccataaac aaattttatg tacatcttgt gacttatact
    29101 cttcaatatt attttcatat gttatttttt cttggatatg ttgtttattt atacaagaat
    29161 tagttccttt caactgattc attgtttcaa atatttcttt ggctttttga ttcatgaaaa
    29221 ctttttcctg actctcaatc gaaaaagcaa cttctctctt ttttaacaaa caaacaactt
    29281 cctttatcaa tctttgatta aaagattgat tataaagtaa ttcaccatga tattgaatgt
    29341 aattacctcc tcctgcaata tatccatcaa cccctaatga taaaacatca tcttgtattg
    29401 tacctatact tcttccagta caaataacaa cactgcaatg attcttttga cataaacgta
    29461 tagcgtgctt tgcagattct gggattccat atacctcatc cctaagcgta ccatctatat
    29521 caagtattaa taatttgtac aatttcatct tcctttctta ctatcaaaat cataatagca
    29581 ttcaaaaaaa aagatatcaa tattttgata tcttttaaaa aatatgttca tttttagcac
    29641 aaattttcac tttcggggaa tatgttcact ttctaaatac atcttgtatt taatataaag
    29701 cagttcaatt aaaataaaat aaggtgttgt tacatcgtag tccagttgtt tatctacaga
    29761 aatagatata gattgaatat acaggttttc atcacataat cttgctaaag gattacttat
    29821 catttttgta atagaaacca tataagttcc tttcattctc atttctttag caaaatcaat
    29881 aattgtagat gtatctccat tcaatgagat aaagaaaatc atatcatctg tttttataaa
    29941 atgattaagc gcctgaatca tatcataacc ataaacatca tatataattt tccctgttgg
    30001 taagaaaatc cttttcatct ctttaacaac tctttcctga gaataacctt ctccaaagac
    30061 gattatacga tttgcctttt tcattctttc aaacataatc gaacaatcct tcttctctat
    30121 atcatctatc accttattat aacaatccat taattggtgt ttactttgat ttttatattc
    30181 tacttctgtt tcatttaagc gtataataac tcttaattca ctatatccag gtaattgtag
    30241 tttttgagca aaacgagaaa gtgcacttgt agatatatgg tatttgtctg caaattcatc
    30301 tatagaaagt ttaatacaat cttctttatg attaagaata cactcacaga tatacttatc
    30361 atttgctgta aatgaattat aatatttatt gaaaagtcct tcaattttca ttcttttctc
    30421 cttctatact ctatgtaatt catatgaagc aaatctaata gagcataaaa tgctcctacg
    30481 acttcataag atatagcttg taatgtatca agtttttgag tttcaacata cagattatac
    30541 tcacaaagtg ttgcaattgt attattatca agcctagtta aagaaatcgt atgtatatga
    30601 ttgttgataa attttgcaat ttcaattcct gattttgttt ctccagacaa agaaatgata
    30661 ataaataaat cacttttttg aaatgattct ctcataaatt caatttcacc tatatcaaat
    30721 aagtcaataa cacatttacc tactgaaaga aatattctct ttatttcttg agctaaactt
    30781 ttctgttcat tacctgtccc ataaatataa attgtttctg catcatatat tattttacaa
    30841 atatcttgaa atgatatttt ttgtaattca ttcattaata gtcgataatt ctcgcaaaca
    30901 tcatgaaaat tattatcatt attaacaaat tctagttgat tatttttaag taaatacttt
    30961 aaatcagaga atgaatctaa tccaattttt ctacaaagcc ttaataaagt agctctagaa
    31021 acattacatt catttgcaat tttttcacac gaaaaattac ggtattctct ttgacaaatc
    31081 aatatttgtt taataataat tttatcattt tcatttaaac tattataact ttggttaact
    31141 aacgattcta atctcatttt ttccactccc taaatattat tttaatatac attagttgct
    31201 ttttctagtg aagagtctta aataataagg ataaaataat catttgattt tatttttatt
    31261 aaaataaaaa taacctgcta aaagcaggca ccaaaaagta cttatccttt cgaacatgta
    31321 ctttagatat tgctttcttc ggaagcttca tctcttcata ctctaaaata gagttttttc
    31381 taactcaaaa gtattttcca tggtagaaat tactttaatt catctgccat ttatttttta
    31441 tcttatttaa taattactat tacttgaata tttacttctt taagtaaatt tcatagttaa
    31501 caaagctaaa actattatta tagatgttaa aatacaaaat tataagtatt gttataaata
    31561 tgcttacagc tacaaatata catgatatat taaaaagaag ctgtaaatta ttatcataca
    31621 tacaagcaac tatgcctcta ttaatccatg ttaattttta ttatttaata caaggagttc
    31681 catgagacat acatatccat tcatatttta aattatccaa ttctcttata gatttcatca
    31741 tctttttata atcccaattc catggattag gataaggaac tatatttcca ttcttatttt
    31801 tgactaaatc acctgcaaat aatacatctt caaaaatcat gcagacatgc cctggagtat
    31861 gaccaggagt atggataatt tttatattcc caatcttcat attctctcca taaggttcaa
    31921 catccttaat gagccttctg gaaattgcct ttccaataaa cttcttaaac ccaggtctat
    31981 ccttctctcc tataataaaa ggtatatcct ctacatgagc ccataccttt gctcctgttt
    32041 tctctttcaa taatttaata ttagatatat gatcaacatc atgatgagtt aataaaatat
    32101 gcttaatatc tgtaagttta atgccaagtg tttttaattc tttaattata tttttcccca
    32161 taaaaggaag acctgtgtct ataagaataa tttctttatc gaacacaata aaacaatttg
    32221 aaccacgagt actatctaac attaatacat tttcttttat cttcataaat aaattcccct
    32281 tatttggtat tttacctata taattaatta ataaagttat aaatagttat aatacttgat
    32341 attaatttta ttttttatta aagtatacta taggtataca aatattatat ttacataagt
    32401 ataccatcag tatacttttt tatcaataga aaggaataat ttatatgtca gaattatcaa
    32461 aaagagataa agaaaaaata caaagagaaa atgagattat tgataaggca gaaaaattat
    32521 tttgtcttaa tggatttgat taaaaaatag ctacgcacac tcgtgacttt agtcatgagt
    32581 tagtagctaa aatagtcagc atatagggaa acctatatgt agagatagga taa
//
LOCUS       DAMJYN010000040        30827 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.041, whole genome shotgun sequence.
ACCESSION   DAMJYN010000040 DAMJYN010000000
VERSION     DAMJYN010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 30827)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30827)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30827
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.041"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(<1..630)
                     /gene="yqeC"
                     /locus_tag="PC466_002040"
     CDS             complement(<1..630)
                     /gene="yqeC"
                     /locus_tag="PC466_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative selenium-dependent hydroxylase
                     accessory protein YqeC"
                     /protein_id="HDF2769424.1"
                     /translation="MELSNIIEKNEIITVVGAGGKTSFINYFANFYRDKLKVLLTTTT
                     KIYVPNDYDNIIITIDGTVIPSICHGITVCGSYINNENKLVSIDSSILDEIVDQFDLV
                     LIEGDGSKRKKLKGWNAKEPVVYHKTTKTIGILDITSFGMNINEENIHRVEIFKKIAN
                     LDTSSINSSSTVSIENLKNIVLNPNGLFKNYSGKRVLFINKVENEKYKNL"
     gene            complement(813..2090)
                     /locus_tag="PC466_002041"
     CDS             complement(813..2090)
                     /locus_tag="PC466_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDF2769425.1"
                     /translation="MSNRIKNIHYGTQRQQLKNLTKKEYQALREMCFLAKNLYNVGTY
                     NVRQHYFNQGEHLNYEANYHVCKENENYKLLNSNIAQQILKEVDSSFRSFFGLIKLAK
                     EGKYDFRGIKSPKYLDKEGFFSIIIGQIRIKEDGILNVPMSPAFKKLYGKVSIKVPQN
                     ILEKKIKEIRIIPKHKARFFEIQYCYEIPKSEEVSNQKNALAIDLGLENLCTCVTNLG
                     DSFIIDGKRLKSVNQWANKQNDKIESLKLKKNITAITRKQFKVWNKRNNQVKDYVNKT
                     CFYIIDYCVKNNIGNLIVGYNAKLEKSDNMERKIYRNFIRIPFGEIKGKLEYLCKIKN
                     INFIRQEESYTSKSDFFADDFLPDINVDNVKKYDFKGERITRGQYKSSVGIIINADVN
                     ASLNILKKSQVVNLSNLQNNPQILKQPQRVRIS"
     gene            complement(2229..4535)
                     /locus_tag="PC466_002042"
     CDS             complement(2229..4535)
                     /locus_tag="PC466_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HDF2769426.1"
                     /translation="MINKGIRKIDSTAIVTGKPLYTEDLIMHKDVLTLKLLRSPHAHA
                     KIKNIDTSKAEKIPGVVGIYTYKDVPQVRYCVPGQTEPEASPYDRVLLEDTVRFIGDE
                     VALVAAEDEKTALKALKMIKVDYEVLKPVFDAREAEGNEVVIHPEKDIVEPYPFGLDA
                     KNNIVSKEFFEFGDVEAKLKESDFVAESSYKTQSQSHCMMETHRSYSYKDINDRIVVV
                     SSLQSPHNVKRIIRKVLGIPSSKIRVIKPRIGGGFGGKNIAATDIFTAFVTMKTGRPA
                     KFVFTRSETFVGSNSRHEMFFDVKVGADKEGNLKAIELKSLNNTGAYGGNGVSVSSES
                     GHNTLPIYNDIDAVRFNARTVYTNRLPAGALRGYGATQGIFAIDSAIDELAHKIGMDP
                     LEFRIKNIIDRYTNGKAAEDEILSCELRQCIEKGKKLINWDDKYPCKDIGNNKVRAVG
                     MAVANHGSGIPRVDMATVTIRMDEDGTYKLLSGLADLGQGADTIQAQIAAEALNTTVD
                     RISIYTGDSDLCPYDTGAFASCTTTVTGNATIKTANKLKDILLSVAESKLGFKKEDLE
                     LGKDRVFVKNDNSKFVLLEELGRESVGGIGFASDDVPVVLEATESFGMLKKIKPFIAG
                     FAEIELDKNTGEYKVINFACVPDCGTVINPTLARIQVEGGVMMGIGFAMYEDPIFDKD
                     GRLLTDSFLQYKVPTKKEVGNILVDFAENFDPGGPYGAKSLGEIVIHTPAPAIANAIF
                     NATGVRLRELPMTFEKVYMGMKNNNKQL"
     gene            complement(4528..5322)
                     /locus_tag="PC466_002043"
     CDS             complement(4528..5322)
                     /locus_tag="PC466_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD binding domain-containing protein"
                     /protein_id="HDF2769427.1"
                     /translation="MVTIKEYSIPQSLEEAYKILISKKNNVILGGCGFIKLSNKNIGT
                     AIDLKDINLNYIKEDEKNILIGADTSLRSLEIDKTIKNYCSGILSSAVSNIVGVQFRQ
                     GARIGASVFSKYGFSDLIPALLVVGAKVRLYNKGILELSEFLDSELSRDILVEVILPK
                     KDAIAVFDSIRKCTGDFSVLNSAMLKENDTYKIAIGARPQKARLALEASNILNKEKDI
                     DKASIVASKELTYGSNMRASKEYRKDMASALVKRMYNAIEEGMYND"
     gene            complement(5428..6786)
                     /locus_tag="PC466_002044"
     CDS             complement(5428..6786)
                     /locus_tag="PC466_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine/pyrimidine permease"
                     /protein_id="HDF2769428.1"
                     /translation="MKAKSTSKFELDGIPPLKEAIPLGLQHLMAMVIGSCLPAILIAN
                     ASGLNHKMSTLLIQAALVFAGLSTLLQLYPIPLFKGFKLGGGIPVIMGATAMFIGAGV
                     SVASKYGLPVLFGSQIIAGIVIIIIGFGLKKIRFIFTPAVSGTIVACMGLGLFPIAIK
                     NLAGGMGNETFGNPINFIVGISVSLMILGLNKYGKGLFKDASILVSIIFGYILSLILG
                     IVNFSSIQEFTLVALPKPLAFGLDIRLEVVVMFSIIYLVEIADIMGACTLSAVGGLNR
                     QVTDEELSSAVLGNGVLSTIGALFSATPMGMFGQNSAIVSNTKVVSKFVLAIGGIGLF
                     LAGISPLLANLIRTIPPCVVGGATLVIFSTLTTSGLRLVSMDGFNQENSMILGLSMAS
                     GIGFMVAPQVLEKFPKFIETLLADSSVVSGAMVAIIIQALYMVKFPGNKSDKVEDKNK
                     SL"
     gene            complement(8133..9224)
                     /locus_tag="PC466_002045"
     CDS             complement(8133..9224)
                     /locus_tag="PC466_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769429.1"
                     /translation="MVMQVQEKILELLYTINEDVVSIKNDMSEVKQEMTVMKEDISEV
                     KQEMTVMKEDMSEVKQEINVLKGDMSEVKQEMTVMKEDMSEVKQEINVLKEDMSEVKQ
                     EMIVMKEDMSEVKQEMTVMKEDMSEVKQEMTVMKEDMSEVRQEINIMKEDISEVRQEM
                     TVMKEDMSEVKQEINVLKEDMSEVRQEINIMKEDMSEVRQEMTVMKEDTSEVKQEINV
                     MKKDMSEVRQEITVMKEDVSEVKSEVNFMQNKINNINEDMNGIKDEVSIANEKLYGIE
                     IKIDSLECEDKSMKEIQIEQNNILGSLLHNSEINKATHDNIEHNIAYIKGDTNSIKED
                     IAEIRRDLNLVELATSKNWSDIVKLKSVK"
     gene            complement(9454..10539)
                     /locus_tag="PC466_002046"
     CDS             complement(9454..10539)
                     /locus_tag="PC466_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HDF2769430.1"
                     /translation="MYNFLGKELKSPLIIGSGPLTYSAAGCKILSDAGAGAVVTKTIR
                     KERAINPAPHMVRNTANALLNNEKWTDFEPEQWIDFEIPQMKRDGTVCIASVGHTIEE
                     SSELVEKVANAGADFIELVSYDYRDLIPMLKDAKERVNIPVIVKLPPMIDEIGDFAKK
                     LEEAGADAITACDSVGPAFRIDIETGQPLLGGNGIGYLSGETIKPITLQRIYEIKKQV
                     NIPIIGLGGCVSGDDALEMIMAGADFVGICSVVILKGAQVISKIHDDLKSNLNRLGYN
                     TIENACGIVHNHMGDVNERLSFEFTYDEEKCTKCKMCERVCAYQARKLNDKMELNEEE
                     CRYCGLCISVCKPKALGRKISCSELNV"
     gene            complement(10575..11888)
                     /locus_tag="PC466_002047"
     CDS             complement(10575..11888)
                     /locus_tag="PC466_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HDF2769431.1"
                     /translation="MIAIKSKYLISSADEIYTNSAAVVENDIIKDILPNEEVEIKYKN
                     IEEIIDKSDAIIMPGFVNGHMHQYGVLSRGIPANVHFTDFEGFLNDYWWPFIENRIGL
                     KEVKATTKASAIELIESGVVAFCDTLEAPNTEEGTLIEQGKILEEIGMKAILSLESCE
                     RISFENGLRCLDENSNLIKWSRENSKLINGIMCTHTSFTCSDRFIKKAKEDAKKLNAP
                     MQFHLCESIYEPNYAEKHFGKKAVDYYNDLDILDETVLASQCVKVNDEEIDILKEKGV
                     KVVHMPLSNCEVGGGFSPVPKMIKKGIKVALGTDGYINDFFEVMRGAFLMHKSVEEDA
                     SVMPANLVFRMATEHGAYVLGLQNSGKIAVGNKADIIVMEDEFKTPVTLDNIFDQIVV
                     QGKKEFISNVYIDGRHILKEKQLVDLDKKAIVKEMKEVACEFWKF"
     gene            complement(11889..14180)
                     /locus_tag="PC466_002048"
     CDS             complement(11889..14180)
                     /locus_tag="PC466_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HDF2769432.1"
                     /translation="MVNKEVRKIDSEAIVTGKPIYTEDLIFHKDVLTIKLLRSPHAFA
                     KIKNIDTKNALKVKGVVNIFTYKDVPNYRYSMVGESYPEASPHDQLILEDVVRYVGDE
                     VAIIAAEDERAAIKAMKLIKVEYEVMTPILDARESEGNKILIHEEDDLFCPFDFGLDA
                     TKNIVSREKMGKGDVEKEFKESDVIVEHSYMTQSQAHCMMETHRAYTYIDTNGRLVVT
                     SANQSAYHMRRQVSKALGIPLSKVRVIKPRIGGGFGGKNIAVTEIYASFVTWMTKRPA
                     KLIYTREETFAMTNTRHQMFFDIKIGADKEGNIKAIDMKALNNTGAYGDNGPSVCSES
                     GHNVLPTYNNVPAIKFDGRTVYTNLVPGGALRGYGATQGTFALDCAIDELAHKLNMDP
                     TEIKLKNIIKKQTEGGIMNFPIRSCALDECIIRGKKLIGWDEKYPVRDIGNNKVRAVG
                     MSVGTHGSGIANIDMAIVNMRMDEDGTYKLFSGSSDLGTGSDTILAQIAAKALNTSID
                     RISVYTGDTDMCPYDTGAYASCTTYVTGNATIKSAESLKQKILKVAQKKLDLPIDDLI
                     LYEDRVCYSEDVEKFVLLSELGKESVGGGNQEVLYSSESYGIQESAKPFLAGFAEIEL
                     DKTTGEFKVINYACSTDCGTVMNPALARIQVEGGVTQGIGLAMYEDPRHGSDGKLQTS
                     NLLQYKVPTKKDIGNIIVDFVDNYEPTGPYGAKSLGEIVIHTPAPAIANAIYNATGVR
                     IRELPITSEKVYMAMKKLNQGGK"
     gene            complement(14170..14964)
                     /locus_tag="PC466_002049"
     CDS             complement(14170..14964)
                     /locus_tag="PC466_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD binding domain-containing protein"
                     /protein_id="HDF2769433.1"
                     /translation="MITIKEYVVPKSLDEAYELLISRKNNIILGGCGFLKLGSKNIGS
                     AIDLKDLALDYINETDDSILIGADTSLRTLELNKVIKNYCNGVISNAVSNIVGVQFRS
                     GARVGASVFAKYGFSDLIPSLLVVDAKVKLYKKGVMNLADFLESELEKDILIEVILPK
                     KDAIGVFDSIRKCTGDFAVLNGAMLKEGSIYKIAIGARPRRAKIAYKASEILSLENDI
                     EKAGEVSSEELSFGSNIRGSKEYRKDMAKALVVRMYNSIGGECDGK"
     gene            complement(15003..15449)
                     /locus_tag="PC466_002050"
     CDS             complement(15003..15449)
                     /locus_tag="PC466_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2Fe-2S iron-sulfur cluster binding
                     domain-containing protein"
                     /protein_id="HDF2769434.1"
                     /translation="MIIKCTINNKEKELSIRPDDFLADTLRENGYVSVKKGCDTGSCG
                     LCTVMVNDKAVLSCNYLTARVDGQHITTLEGVLDEAKKFGDFLADEGADQCGFCAPGF
                     IMMVLAMKRELQNPTEEEVIDYVNGNLCRCTGYKGQLRAIHKYLNT"
     gene            complement(15521..16927)
                     /locus_tag="PC466_002051"
     CDS             complement(15521..16927)
                     /locus_tag="PC466_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2769435.1"
                     /translation="MMDILIKNAIIVTVNKEREVIFDGALVVKDNKIADIGNSKEIES
                     KYTDVKKIIDAKGKVLFPGFINTHNHLFQTLLKGLGDDMVLKDWLETMTFPAANYLEP
                     KDTYDAAMLGCIEGLRSGITTMVDYMYPHSKPGLCDGIIDAYKELGIRGILGRGCMNT
                     GAQFGVHPGIMQDVETVEKDVRRLFEKHHNTENGRIKIGVAPAAIWSNSQEMLEMLWR
                     VVKEYDDALFTVHISETPFDREAAKELHGQYDIDVLEKLGILGPNVLMVHCVYLTEKD
                     MELTKKYDMKVSHNTASNMYLSSGVAPVPEMLKKGITVSLGVDGAASNNSQDMLELMK
                     LTALQHKVNKCDPLAMSAEKVLELATIDGARAIGMEDEIGSLEIGKKADLLIFNPMLS
                     PKAIPMHNPVSTLVYSSSMKNIESVIVDGNIIMEDSKILTANEEKALKDAQDTAERLC
                     VRGTIKNRMEGHKWNSLY"
     gene            complement(16945..18315)
                     /gene="hydA"
                     /locus_tag="PC466_002052"
     CDS             complement(16945..18315)
                     /gene="hydA"
                     /locus_tag="PC466_002052"
                     /EC_number="3.5.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropyrimidinase"
                     /protein_id="HDF2769436.1"
                     /translation="MGTILRGGTIITSDKTYISDLRIEDEKIVEIGNNLEINGDKVID
                     ATGKIVIPGGIDTHTHFDMNAGSITTADNFETGTRAAIAGGTTTILDFAEANEGENLL
                     QGVEAYHKKASGNCYCDYGFHMTITCLNKDTFNHMEKLISDGIVSFKMYMAYDGMKVD
                     DGTIYRVLKKARDLGCIVGFHCENGDLLDVLIEENIQNGNLEPKYHPLTRPNIVEKES
                     VSRLADITKLSNSKSYVVHLSCRESLETVKMAREKNIDMIVETCPQYLLLEDNLYNKN
                     KFEGAKYVMSPPLRKKEDINYLWEGLSSGDIQTVGTDHCSFNFKGQKDLGIDDFSKIP
                     NGAPGVEHRLALLYTYGVLENRISVNKFVEVTSTNAAKIFGMYPKKGEIAVGSDADIV
                     ILNINKEETISYKTQKQNVDYTPYEGFKVKCKVEDVFLRGNHVVQSCNVKEHPTGQYI
                     KRKITK"
     gene            complement(18448..19635)
                     /locus_tag="PC466_002053"
     CDS             complement(18448..19635)
                     /locus_tag="PC466_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgeY family selenium metabolism-linked
                     hydrolase"
                     /protein_id="HDF2769437.1"
                     /translation="MLNEQRKQEVTEICQKLIQNPSSSGNEEGVVKAIEESFEKLGFD
                     SWSRDRYGNIVGCIKGNKPGKKILFDGHIDTVPVPDASKWSVPPFEGKIVDGKIYGRG
                     TSDMKGQYTAMMSAVAYFAKDTNRDFAGELYVAGVVHEEIFEGVSAREISKAVQPDYV
                     VIGESSELNLKIGQRGRGEIVVETFGKPAHSANPEKGVNAVYKMANVIQKIQQLVPPT
                     HPVLGDGILVLTDIKSSPYPGASVVPDYCKATFDRRLLVGETREGVLAPIQALLDEMM
                     KEDPELNAKVSYAVEKADCYTGNTIESERFFPGWLYDEEDEFVQAAYKGLKEAGIDSE
                     ITQYSFCTNGSHYAGEAGIKTIGFGPSKENLAHTIDEYIEQEQLFIGTEGYYGILKSV
                     YGK"
     gene            complement(19762..20976)
                     /gene="dpaL"
                     /locus_tag="PC466_002054"
     CDS             complement(19762..20976)
                     /gene="dpaL"
                     /locus_tag="PC466_002054"
                     /EC_number="4.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopropionate ammonia-lyase"
                     /protein_id="HDF2769438.1"
                     /translation="MLKEIKWKVNNLPKGDKENCIKFLNEEEITKVRNFHKSFPQYKE
                     TPLANLEGLAKKLGVAGVYVKDESYRFGLNAFKVLGGSYSMGRYLAQRLDTDISELGY
                     DKLTSKEIKEKLGEITFFTATDGNHGRGVAWTANKLGQKSVVLMPKGSSEFRLNKIKG
                     EGADASITDLNYDDAVRLANDYAEADDHGVMVQDTAWDGYEEIPAWIMQGYGTMAQEA
                     IEQLKEYGVDRPTHVFVQAGVGSLAGAVQGYVASIYDECPITVVVEADEADCYYKSAE
                     AGDGKPRFVGGDMPTIMAGLACGEPNTIGFEVLKNHAAAFVSAPDWVSAKGMRTLGNP
                     LNGDEKVISGESGAVTTGLLVAAMEREDLADLRKDLKLDENSRILLISTEGDTDPDKY
                     RSIVWDGEYPSI"
     gene            complement(21339..22010)
                     /locus_tag="PC466_002055"
     CDS             complement(21339..22010)
                     /locus_tag="PC466_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HDF2769439.1"
                     /translation="MAKILGICGSPRKGATEYAVLEALKEAETIPGIETEYWSVRGKK
                     ISPCVHCDACIRKETMCIIKDDIQELEQKILEADGIIVGSPVYDMNITAQLTAVFNRL
                     RPMYLVHPGKLQNKVGAAITTGGTRYGGQELTKLPIINFFLMHEMLVSGGLGGCYIGG
                     TIWSKDGKAKGAQEDETGMDTVKRLGKGAAEAVMVSKFGLEKWNVVKEELDVKKDEKS
                     PLRDH"
     gene            complement(22093..24309)
                     /locus_tag="PC466_002056"
     CDS             complement(22093..24309)
                     /locus_tag="PC466_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HDF2769440.1"
                     /translation="MEKVIGKSYPLKDAALKVTGQMKYVADMKPQNVLYAKMLLSPVA
                     HAKIKSIDTSEAEKVVGVRAIATYLNTSQRKYNGSLRFYEHNIPENEVIFSDTVRFVG
                     DRVAAVAAETPEIAEKAVKLIKVEYEELPAVFTIQDAIKEDAICIHGDSNIVSQNNIN
                     GGDVEKGFKECDYIFEDEYSTPAIHHSAIETHSVIAHYDYNDKLTVHTPCQNTFGFRI
                     ILSQIFGMSLNKVRVIRPAIGGSFGGKLELTIEPVAAALSKMTRRPVKMVLTRKESMI
                     STRTRHGSFVKLKTGVNKDGEVIAQDIKIYTNTGAYASSALNVIGALSHKVFKVYKIP
                     NIKFTGMPVYTNTPIAGAMRGYGSPQIFMAQQAQFAKIAKEIGMDLVDFQNKNAVEPD
                     DVDIIFRGSLGNPRVLDCIEQGKKMFKWDEKKKLPKEEGKYLRGIGMAIGAHGNGVFG
                     AHRDVVTLTLKLNEDGTLTLLTGAHDMGNGVVTMQTMMVAEVLGITPDKVDTFETDTD
                     ACTFNLGDYASRGVFVEGGGAKKTAEKLKNLIVEEAEKLLETSKEDLYLDNGYVISKL
                     DENVKASLSDVAVYSQSKSLRELTVVEDYSSPAGLTSYGVHFAEVLVDKETKDIKVVD
                     FVAVHDVGRVINPLNLEGQLEGGIHMGLGYALSEELAFDEQGRPKATDFKTYKLFRTV
                     DMPKCQVAFVNSYEKAGPFGGKSIGECAVVPVAPAVANAVYNATDVEIHSLPIKLK"
     gene            complement(24312..24782)
                     /locus_tag="PC466_002057"
     CDS             complement(24312..24782)
                     /locus_tag="PC466_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(2Fe-2S)-binding protein"
                     /protein_id="HDF2769441.1"
                     /translation="MEKIKLNINDYMYEIEVEKNETLLHVLREKLNLTGAKQGCNSGS
                     CGACKVLIDGVDMKSCKLLAKNCEGKVIYTIESFANGENLHPIQEAFIEVGAVQCGYC
                     TPGMIITTQALLNRNASPNEDEIKEAFKENLCRCTGYVKIIEAVKLSAARLGGR"
     gene            complement(24844..26238)
                     /locus_tag="PC466_002058"
     CDS             complement(24844..26238)
                     /locus_tag="PC466_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2769442.1"
                     /translation="MIDILIKNAIIVTVNKDRDVIFDGAIAIQGDRILDIGNTVDIEP
                     KYLDAKKVIDANGKVIFPGFINTHNHLFQVLLKGLGDDMALHEWLNTMMFPSAKFLTE
                     QDTYDAAMLGCMEGLKSGITTMVDYMHTHNRPGLTDGIVKAYKDLGIRGVVGRGCIDL
                     GIHKELIEDVETVEKDLRRVFEKYHNSENGRIKICVAPSSMWAISEEMGKMLWNIVKE
                     YDSYFTVHISETEFARTATKDIHGEIDIKLLEKWGIVGPEVVAVHCVCITDEDMEMLK
                     KYDIKVSHNVASNMYLASGVAPVPEMLKKGINVSLGLDGAASNNAQDMVELMKLTALQ
                     HKVNNCDPLAISAEKVLEMATIEGARTLRMEDEIGSLEIGKKADLVIFNSMLSPKSIP
                     LHNPVSTLVYSASMHNVESVLVDGNVILENGKVTTIESEEQVLLNAQLAAEELCKRAN
                     VTNRMEGHKWNSLY"
     gene            complement(26311..27672)
                     /locus_tag="PC466_002059"
     CDS             complement(26311..27672)
                     /locus_tag="PC466_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine/pyrimidine permease"
                     /protein_id="HDF2769443.1"
                     /translation="MKTRNTSKYDVDGIPPLKESIPLALQHLLAMIVGNMVPAILIAN
                     VVGLNQGQATMLIQGSMLAAGLATFLQLYPIPLFKGFKLGSRLPVMMGMSYVFLGACL
                     SVAAKDGLAALFGAQIAAGVIVFFVGFGVKKIRHIFTPIVSGTIIACMGLGLFATAIK
                     NLAGGEGTQTFGSPINFTVGVIVAFVIIMINKYGKGLVKNSSILIGILVGYAISLVLG
                     LVDFSAVQGAAIVSLPTPAAFGLEFRPELIVMFTIIYIIGIADMMGACTIATVGAMDR
                     EVTDEELASVVLGNSITSIISSLFAALPTGVFSQNTVIVSMNKVTSRFVIALGALVLL
                     LAGISPALGAIMTTIPSCVVGGATLVVFSSIAMSGFSIMSMDGFTEENNLIAGVSIAT
                     SMGLTTAPQVLDQFPETIGTVLGGSSIVSGAIIAILLQTLFKLKSRKSAENVTSNLEE
                     NIG"
     gene            complement(27970..29292)
                     /locus_tag="PC466_002060"
     CDS             complement(27970..29292)
                     /locus_tag="PC466_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HDF2769444.1"
                     /translation="MFDIDGRPPILKCLPLSMQHILAMIVGTVTVPIVVGGAVGVSPT
                     QITLLVQYALIIAGISTLIQLYPIGNIGSRLPIIFGVGFTYVPTLVAVGGNYGLASIL
                     GAQLIGGVATVLIGIFIKKIRKFFPNIVAGTVVFTIGLSLYPIAINYMAGGVNSPTYA
                     SMQNWAVAAITLVVVIGLSQFAKGYAKLAAIFLGIIVGYCVSLVLGIINFDPIREATW
                     FAIPKPLEFGMEFDMPVIISVVIVSIINAVQAIGDLSATTMGGMDRNITDKELSSGVI
                     GSGICTMIGALFGGLPPSSYSQNVGMVAMNKVISRFVLGIAGIFMLLSGFVPKFGALM
                     TTIPYSVLGGATISIFSMITMTGIKLIITEELSSRNITIVGLAIALGMGITSVPAAQE
                     AFPSFVKLVFGESPIVIATLVAFVLNLIIPNKSLEDEAKERAVMEETN"
     gene            complement(29648..30688)
                     /locus_tag="PC466_002061"
     CDS             complement(29648..30688)
                     /locus_tag="PC466_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2769445.1"
                     /translation="MDKHSDSVMYGGMEVYNIWGTTTVDSIIGESDVMRALKNRICKI
                     GNSDSTVAITGESGTGKELIARAIHLAGNRGNKTFVAINCAAIPEPLLESELFGYTKG
                     AFSGADSKGKIGKFELANGGVVFLDEIGDMPIQLQSKLLRVLQEKKFTRIGSNELIDI
                     DVRIISATNRDLFELVKENKFREDLYYRLNVIPLEVPPLRERGDDIQILINNFIDKYS
                     RKMKKNVYHIEPDVEQMLLKYPWPGNIRELENTIELALNLLEEDGIIHKGIINRKILE
                     YFKLNNINIKLLEESDYEISMEQDILTLEEFERAYIKKVLKFYGNDTKSKKLAAKKLG
                     ISLATLYRKIDV"
BASE COUNT         9299 a         6106 c         3376 g        12046 t
ORIGIN      
        1 taaattttta tatttttcat tttcaacttt attaataaat aatactcttt ttccagaata
       61 atttttaaat aatccatttg gatttaatac tatatttttt aagttttcaa tacttactgt
      121 agaactacta ttaatactac ttgtatctaa atttgctatt tttttaaata tttctactct
      181 atgtatattc tcttcattaa tattcattcc aaatgatgtt atatctaata tccctatggt
      241 ttttgtagtt ttatgatata ctactggttc tttagcattc caacctttaa gtttttttct
      301 ctttgagcca tctccctcta ttaaaactaa atcaaattgg tctacaattt catccaaaat
      361 agaggaatca atacttacta atttattttc attatttata taactgccac agactgttat
      421 tccatgacaa atagatggaa taacagttcc atctattgta ataattatat tgtcataatc
      481 gtttggtaca tatattttag ttgttgttgt aagaagaact ttcaatttat ctctataaaa
      541 atttgcaaaa tagtttataa acgaagtttt tcctcctgct ccaactacag ttattatttc
      601 attcttttct attatatttg atagttccac actttcacct cttataacca gttttctaat
      661 ctcttaatta ttatagttag acctttttag taaaagtgat ttttgaaatt ccataaactc
      721 gaaagtaaat agattctgtt gtaaacaaca aggcggatcc aattcgccgc taagctgtaa
      781 gcttacgcta tcagtttatc ttttaaatat aattaagata ttcttactct ctgtggttgc
      841 tttaatattt gaggattatt ctgtaaatta gataaattaa ctacttgtga tttttttagt
      901 atattaagac tcgcatttac atctgcattt ataatgattc caacactgga tttgtactgt
      961 ccacgtgtta ttctttcccc tttaaagtca tattttttaa cattgtccac attgatatca
     1021 ggtagaaaat catcagcaaa aaaatcagac ttactagtat agctttcttc ttgcctaata
     1081 aaattgatat tttttatttt acatagatat tctaattttc cttttatctc tccaaatggg
     1141 attcttataa aatttctata tatttttctc tccatattat cacttttttc taacttagca
     1201 ttatatccta caattaaatt tccaatatta ttttttacac aataatcaat tatataaaaa
     1261 caggttttat ttacatagtc tttaacttga ttatttctct tattccaaac tttaaattgt
     1321 tttcttgtta ttgcagttat attctttttt aattttaagg attctatttt atcattctgt
     1381 ttgtttgccc actgattcac agattttagc ctttttccat ctatgataaa actatcacct
     1441 aaattggtaa cacatgtaca taaattttct aaacccaagt ctatagctag tgcatttttt
     1501 tgatttgaaa cttcctctga tttcggtatt tcataacaat actgaatttc aaagaaccta
     1561 gctttatgtt taggtattat tcttatttct ttaatttttt tctctagtat attttgtgga
     1621 acttttatac ttactttccc atatagtttt ttaaatgctg gagacatagg tacatttaaa
     1681 atcccatctt ctttgattct tatttgacct attattatgc taaaaaatcc ttctttatct
     1741 aaatatttag gtgattttat ccctctaaag tcatatttcc cttctttggc taatttaatt
     1801 aacccaaaaa atgacctaaa cgaactgtct acttctttta atatttgttg cgctatatta
     1861 ctattgagaa gcttatagtt ctcattttct ttgcatacat gataattagc ttcatagtta
     1921 agatgttctc cttgattgaa ataatgctgt cttacattat atgtaccaac attatataag
     1981 ttcttagcta agaagcacat ctctcgtaga gcttgatatt cttttttagt taagtttttt
     2041 aattgttgtc tctgagttcc atagtgtata ttttttattc tgtttgacat gaactcacct
     2101 cctttagaat atactctact agacattata tacggtattt ttacaaaaca ccatatataa
     2161 tgtccattta attactttat tttacaaaat aatttaaatt tacttgcttt tatacacctt
     2221 attatttatt ataattgttt attattattt ttcataccca tataaacttt ttcaaaagtc
     2281 ataggaagct ctcttaaacg aactcctgta gcattaaata ttgcatttgc tatagctggc
     2341 gctggtgtat gtataactat ttctcctaat gatttagcac cataaggacc tcctgggtcg
     2401 aaattctcag caaaatctac caatatattt ccaacttctt tttttgtagg aactttatac
     2461 tgtaggaaac tatctgttaa taatctccca tctttatcaa atatagggtc ttcatacatt
     2521 gcaaacccta tacccatcat cacaccacct tctacttgta ttctagctaa agttggattt
     2581 ataactgttc cacaatcagg tacacatgca aaatttatga ccttatattc gcctgtattt
     2641 ttatctaatt ctatctctgc aaatcctgct ataaatggtt ttattttttt caacatgcca
     2701 aaagattctg ttgcttccaa aactactggt acatcatcac tagcaaatcc tattcctcca
     2761 acagattctc tacccaattc ctctaataga acaaacttgc tattatcgtt tttaacaaaa
     2821 accctgtctt ttcccaactc taaatcttct tttttaaatc ctagctttga ctctgcaact
     2881 gaaagtaata tatcttttaa tttatttgct gtctttattg ttgcatttcc tgtaaccgtt
     2941 gttgtacaag aagcaaatgc tcctgtatca tagggacata aatctgaatc acctgtataa
     3001 atagaaattc tatctacagt agtatttaaa gcttccgcag caatttgagc ttgaattgta
     3061 tcagcccctt gacctaagtc agcaagacca gataatagtt tatatgtgcc atcttcatcc
     3121 attcttatag tgactgttgc catatctaca cgcggtatac cagaaccatg atttgctact
     3181 gccataccta ctgctcttac tttgttgttt cctatatctt tacatggata tttatcatcc
     3241 caattgatta atttcttgcc cttttctata cattgtctca gctcacaact taatatttcg
     3301 tcttcagctg cttttccatt ggtataccta tctattatat ttttaattct aaattcaagt
     3361 gggtccattc caatcttatg tgccaattca tcaatagcac tatctattgc aaatattccc
     3421 tgtgtagcac cataccctct aagtgctcct gctggtaacc tattagtata tactgttcta
     3481 gcattaaatc taacagcatc aatatcatta tatattggta aggtattgtg tccagattcg
     3541 gaagaaacag agacaccatt cccaccataa gcacctgtat tgtttaatga ctttagctct
     3601 attgctttta aatttccttc tttatctgca ccaactttaa catcaaaaaa catttcatgt
     3661 ctactattag aacctacaaa agtttcactt cttgtaaata caaattttgc tggtctacca
     3721 gttttcatag taacaaatgc agtaaatata tctgttgctg ctatattctt tcctccaaat
     3781 ccaccaccta ttctaggttt aattactctt atttttgaag atggtatacc caatactttt
     3841 ctaattattc tctttacatt gtgtggtgat tgtaatgatg aaactacaac aattctatca
     3901 tttatatctt tatatgaata tgacctatga gtttccatca tgcaatgcga ttgactttgg
     3961 gttttgtatg aagattcagc cacaaaatca ctttctttaa gcttagcttc aacatctcca
     4021 aattcaaaaa attcttttga tactatatta ttttttgcat ccaatccaaa agggtatggc
     4081 tctactatgt ctttttctgg atgtataaca acttcatttc cttctgcttc tcttgcatca
     4141 aacacaggct ttaaaacctc ataatctacc tttatcattt ttaaggcttt aagtgctgtt
     4201 ttctcatctt cagcagccac taaagctact tcatctccaa taaatctaac tgtatcttca
     4261 agtaaaactc tatcataagg tgatgcttct ggttctgttt gacctggcac acaatatctg
     4321 acctgtggta catctttata cgtataaata cccacaaccc ctggaatttt ttcggctttt
     4381 gatgtatcta tattctttat cttagcatga gcatgtggac ttctaagtag ttttaatgtc
     4441 aaaacatctt tatgcataat gaggtcttca gtatatagag gttttcctgt gacaattgct
     4501 gtactatcta tctttcttat ccccttatta atcattatac attccctcct caatagcatt
     4561 atacatcctt ttaactaatg cacttgccat atcctttctg tactctttac tagctctcat
     4621 attacttcca taagtaagtt ccttactagc aacaatagat gccttatcta tatctttttc
     4681 tttatttaat atattactcg cttcaagtgc taatctagct ttttgaggtc ttgccccaat
     4741 tgctattttg taagtatcat tttcttttag cattgctgaa tttaatacag aaaaatctcc
     4801 tgtgcatttt cttattgagt caaaaacagc tatcgcatct ttttttggta gtattacttc
     4861 gaccaatata tccctactta attcactatc caaaaactca cttaactcta gtattccttt
     4921 attgtataat ctcaccttcg ctccaacaac caaaagcgct ggtattaagt cagaaaagcc
     4981 atactttgaa aatacacttg caccaattct agccccttgt ctaaattgaa caccaactat
     5041 attagaaaca gcgcttgaaa gtattccact acagtaattt tttatagttt tatcaatttc
     5101 taaacttcta agtgaagtat ctgcacctat caaaatattt ttttcatcct cttttatata
     5161 atttagattt atatctttta aatctatcgc tgttcctata tttttattac ttaattttat
     5221 aaatccacat ccacctaaaa taacattatt ttttttagaa attaaaattt tatatgcttc
     5281 ttctaaactc tgtggaattg aatattcctt tatagtaacc atcttatccc ccatcattaa
     5341 cttattaaaa cacaaaagtt tttaataaat cttttattta tatttataat tgtagtatat
     5401 ttaattcaca tatattaaac ctttacatta taaactttta tttttatcct caaccttatc
     5461 acttttattt ccaggaaatt ttaccatata taaagcttga attattatgg ctaccattgc
     5521 tcctgaaact acacttgaat ctgcaagtaa tgtctctata aattttggaa atttttcaag
     5581 aacttgagga gctaccatga atccaatacc agaagccata gaaagaccta atatcatgct
     5641 attttcttga ttaaatccat ccatactaac aagtcttaaa ccagatgttg taagagttga
     5701 aaatataacg agtgttgctc ctccaaccac acagggagga attgttctta ttaaattagc
     5761 taataaaggc gatattcctg ccaaaaataa tccaattcct ccaatagcta gtacaaattt
     5821 acttacaacc tttgtattgg aaacgattgc agaattttgt ccaaacatcc ccattggagt
     5881 tgcagaaaat aatgcaccta ttgtagagag tactccattt cctaaaacag cagaagaaag
     5941 ttcttcatct gttacttgtc tattaagccc tcctaccgca gaaagtgtac aagcacccat
     6001 tatatcagct atctcaacta aatatattat tgaaaacatt acaacaactt caagtcttat
     6061 atctagccca aaagcaagtg gttttggaag cgcaaccaaa gtaaactcct gaattgaaga
     6121 aaaatttact atacccaaaa ttaatgataa aatgtatcca aaaattatgc taactaatat
     6181 tgatgcatct ttaaataatc cttttccata cttatttaat cctaatatca taagagatac
     6241 agatattcca actataaaat taattggatt cccaaaagtc tcattgccca tacccccagc
     6301 taagtttttt atagctattg gaaaaagtcc aagacccata catgcaacta ttgttcctga
     6361 tacagctgga gtaaatataa atcgtatttt tttaagacca aaaccaatta taattattac
     6421 tataccagct attatttgag agccaaataa tactggtagt ccatacttac ttgcaacaga
     6481 taccccagct cctataaaca tagctgtagc tcccattata actggtattc ctcctcctaa
     6541 tttaaaacct ttaaacaaag gtattggata taattgtaat aaagttgata atcctgcaaa
     6601 aactaatgcg gcttgaatca ataatgttga catcttatga ttaagtccag atgcatttgc
     6661 aatcaatatc gctggtaaac aactacctat taccattgcc attaagtgtt gtaaccctaa
     6721 aggtattgct tcctttagtg gtggtattcc gtctaattca aattttgatg tactttttgc
     6781 tttcataata aaaactcccg ttacataaaa cttattgaat tatataaata cttaaaaatc
     6841 taatatatta aattaatgat gttcataaat atcaactata ctccaacata tatttaagtt
     6901 tttagtctta aaaaacagat gcaataaatt taattattaa caaatacacg tattctttaa
     6961 ttttgtatac attatatacc atgctttaca aatataagag tattatagct atgaattttt
     7021 aattttttat agtaaattta attcaattta aatctttcaa tcttaatcat tataagttat
     7081 aagttttcat aagtatttac atgtttcaag ttttaaacat ttacctataa acgctacttt
     7141 atagatgtca cttcaaatct agtgacctca tactttcata tgagcgtaga ctatttcttc
     7201 atcttcagca ttacctgcta agagcaaccc gtttccacta tcaatcgctt atagtgtact
     7261 ctctctcgag atagtcgttt gaccttccta tttctaggct tggcgaccaa atgtccattt
     7321 ttaagtactt aggctctcac catataccat cctcactatt gtttctggtt ttcaccacat
     7381 tcataaaagt ttctttctat cttttattgt agttgcaagg ctttaggatt tactggtttt
     7441 aaagttgtgt cctacataga tttctctatg tacggggcca aaagtacaat ttatttaaca
     7501 tactttgctt taccccctgt aaataatatt atttactctt tcactgtttt tgttattaaa
     7561 ttaattaaat atcaattaat ctaagcataa aataattatt taatttaaac tcaaaatatt
     7621 tatgaatatt ttataatata attctcataa gacagaaaaa cttaataagc tatgtatctc
     7681 agttgtacca atgtactctc ctttactata tttgtatctg caacataaaa tatacaagtt
     7741 tctatctatt tatagatata tatatctata agcaaaatag taatattatt tttatagtaa
     7801 aaattttatt catattacta tttataattt ttatagagca attttagtgc caatatttgc
     7861 atacatttgt atagtataaa atttttatgt tctcattgat aaaattttac ttatttcaag
     7921 cgttttattc gattttatca tctaaatttt aggttttatt tttataaatt aattgtattt
     7981 acataaaaaa aaagacctaa aaacaaattt ttaacggtct tttctcaatt ttttattttc
     8041 atttctaaaa tttataataa atagtaagaa cactataaat tcttttatat aaaattctta
     8101 gtttgtggat gataaattag tgaattaaaa tactacttta ctgattttag tttgacaata
     8161 tcactccaat ttttactagt ggctaactct actaaattta agtctcttct tatttcagct
     8221 atatcctctt ttatagaatt agtgtcacct tttatatatg ctatgttatg ttctatatta
     8281 tcatgagtag ctttatttat ttcagaatta tgtaataaac ttcctaaaat attattctgt
     8341 tctatctgta tctctttcat tgatttatct tcacattcta gactatcaat cttaatttca
     8401 attccatata atttttcatt tgctatggat acctcgtcct taattccatt catatcttca
     8461 ttaatgttat ttattttatt ttgcataaag tttacttctg atttaacttc ggaaacatct
     8521 tctttcatta cagttatttc ttgtcttact tctgacatgt cttttttcat tacatttatc
     8581 tcttgtttta cctctgatgt atcttctttc attacagtca tttcttgtct tacttcagac
     8641 atatcttctt tcattatatt tatctcttgt cttacttcgg acatatcttc ttttaataca
     8701 tttatctcct gttttacttc cgacatatct tctttcatta cagtcatttc ttgtcttact
     8761 tcggatatat cctctttcat tatatttatc tcttgtctta cctctgacat atcttctttc
     8821 attacagtca tttcctgttt tacttccgac atatcttctt tcattacagt catttcctgt
     8881 tttacttccg acatatcttc tttcattaca atcatttcct gttttacttc cgacatatct
     8941 tcttttaata catttatttc ctgttttact tccgacatat cttctttcat tacagtcatt
     9001 tcttgtttta cttccgacat atctcctttt aatacattta tctcctgttt tacttccgac
     9061 atatcttctt tcattacagt catttcttgt tttacttctg atatatcttc tttcattaca
     9121 gtcatttctt gttttacttc cgacatatca ttttttatgc taactacatc ttcatttata
     9181 gtatataata actctaaaat cttctcttgc acttgcatca ccatccctat taattattat
     9241 aacattttac acaaatgcta tacaatgtta acatatatat cagaattatt aaaattttaa
     9301 ttaaacaaaa ttgattcact ttattacttc aaaactaatt aatatctaaa ataactacaa
     9361 ataaacaaaa ataaggtcaa caacaaaaaa ggcttatctc tttgagatag cctttcttat
     9421 ttttatttaa aactttgttt tttataaaat aatctataca ttcagctctg aacatgaaat
     9481 ttttcttcca agtgcttttg gtttacaaac tgatatacaa agtccacaat atctacactc
     9541 ttcttcattc aattccatct tatcattcaa ttttctcgct tgatatgcac aaactctctc
     9601 gcacatctta catttagtac atttttcttc atcataagta aactcaaagc taagtctttc
     9661 attaacatct cccatatgat tatgtactat accacaagca ttttctatag tattatatcc
     9721 taatctatta agattagatt ttaaatcatc atgtatttta gatattactt gtgcgccttt
     9781 taaaattact actgaacata taccaacaaa gtcagcacct gccataatca tttctaaggc
     9841 atcatctcca cttacacatc cacctaagcc aattattggt atattaactt gtttttttat
     9901 ttcatatatt ctctgtaaag ttattggctt aatagtttct ccacttaaat atcctattcc
     9961 atttccacct aataaaggtt gccctgtttc tatgtctatt ctaaatgctg gtcctacaga
    10021 gtcacaagca gttattgcat ctgctcctgc ttcttctaat tttttagcaa aatcgcctat
    10081 ctcatctatc ataggaggaa gtttaactat tacaggtata tttactcttt cctttgcatc
    10141 tttaagcatt ggtatcaaat ctctatagtc ataagatact aattcaataa agtcagctcc
    10201 tgcatttgca actttctcta ctaattcgct actttcttca attgtatgac ctactgaagc
    10261 tatacagaca gtcccatctc ttttcatttg tggtatttca aaatctatcc attgctctgg
    10321 ctcaaaatct gtccattttt cattatttaa aagagcatta gctgtatttc taaccatatg
    10381 tggtgctgga tttatagctc tttcttttct tatagtctta gtcacaactg cccctgctcc
    10441 tgcatcactt aatatcttgc atccagctgc actatatgtt aatggtcctg aacctattat
    10501 aagtggtgat tttaattctt tacctaaaaa attatacatt atctgcttcc ccttttcata
    10561 tatatttaca ttcgttaaaa tttccaaaat tcacaagcaa cttctttcat ttctttaaca
    10621 atagcttttt tatctaaatc aactaactgt ttttctttta aaatatgtct accatctatg
    10681 tatacatttg atataaattc ttttttaccc tgaactacta tctggtcaaa tatattatca
    10741 agagtcacag gagttttaaa ttcatcttcc ataactatta tatcagcctt attaccaact
    10801 gctattttac cagaattttg aagtcctaat acataagcac catgctctgt tgccatccta
    10861 aatactaaat ttgctggcat tactgatgca tcttcttcaa ctgatttatg cattaaaaat
    10921 gcacctctca taacttcaaa aaaatcattt atatatccat cagtacccag tgccactttt
    10981 atgccttttt taatcatttt tggtactgga gaaaaacctc cacctacttc acagttgcta
    11041 agaggcatat gaaccacttt tacacctttt tcttttaata tatctatttc ttcatcattt
    11101 acttttacac actgagatgc taatacagtt tcatccaata tatctaaatc attatagtag
    11161 tcaactgctt ttttgccaaa atgtttttca gcatagtttg gctcatatat actctcacat
    11221 aaatgaaatt gcattggtgc atttaatttt tttgcatctt ctttagcttt cttaataaat
    11281 ctatcagaac atgtgaagct tgtatgtgta cacattattc catttattaa tttactattt
    11341 tctctactcc actttattaa attagaattt tcatctaaac atctaagtcc attttcaaag
    11401 cttattcttt cacaactttc taaggataaa atcgctttca tgcctatttc ttctagtatt
    11461 tttccttgct caattaaagt tccttcttct gtatttggag cttctagggt atcacaaaaa
    11521 gctaccacac cagattctat aagttctatt gctgatgctt tagttgttgc cttcacttct
    11581 ttcaatccaa ttctattttc tataaatggc caccaatagt catttaaaaa accttcaaag
    11641 tcagtaaaat gtacatttgc cggtattccc ctagaaagaa ctccatattg atgcatatga
    11701 ccattgacga atcctggcat tattatagca tctgatttat ctattatttc ttcaatattt
    11761 ttatatttta tttcaacttc ttcatttggc aatatatctt ttataatgtc attttctact
    11821 acagcagcag aatttgtata tatttcatca gcagaagata ttaagtattt acttttaata
    11881 gcaatcattt atttacctcc ctgatttaat tttttcatgg ccatataaac tttctcagaa
    11941 gttataggaa gttctcttat acgaactcct gtggcattgt atattgcatt tgctattgct
    12001 ggtgcaggtg tatgaataac tatttctcct aaagatttag ctccatatgg acctgttggc
    12061 tcataattat ctacaaaatc aacaattatg tttcctatat ctttttttgt tggaactttg
    12121 tattgtaata gattagaagt ttgaagcttt ccatcagaac catgtctagg gtcttcatac
    12181 attgcaagcc ctataccttg agttacacca ccttcaactt gtattctagc aagtgcagga
    12241 ttcataactg taccacaatc tgtagaacaa gcataattta ttactttaaa ctcccctgtt
    12301 gttttatcta actctatttc agcaaatcct gctaagaatg gtttagcact ctcttgtata
    12361 ccataagatt cagatgaata taaaacttct tgatttccac caccaacaga ttcttttcct
    12421 aattcactta acaaaacaaa cttctctaca tcttcactat aacaaactct gtcttcatat
    12481 agtattaaat catctattgg taaatcgagt ttcttctgtg ctacttttaa tatcttttgt
    12541 tttaaacttt cagcagattt tattgtagca tttccagtta cataagtagt acaagaagcg
    12601 tatgcaccag tatcatatgg acacatatct gtatctcctg tataaacgga aattctatca
    12661 atagatgtat tcaatgcttt tgcagctatt tgtgcaagta ttgtgtcaga accagttcct
    12721 aagtctgaag acccagaaaa caacttataa gttccatctt catccatcct catatttact
    12781 attgccatgt ctatgttggc tataccagaa ccatgagttc ccacagacat tccaacagcc
    12841 ctcaccttat tgtttccaat atccctaaca gggtactttt catcccatcc aataagtttt
    12901 ttacctctaa ttatacattc atcaagtgca caacttctta ttggaaaatt cattattccg
    12961 ccttcagttt gtttttttat aatattcttt aactttattt ctgttgggtc catattaagt
    13021 ttatgcgcta attcatcaat tgcacaatca agtgcaaatg taccttgtgt tgctccatat
    13081 cctcttaatg ctcctcctgg aactaaatta gtatatacag ttctcccatc aaattttatt
    13141 gcaggtacat tattatatgt tggaagtaca ttatgacctg attcagagca aactgaaggt
    13201 ccattatcac cataagcgcc tgtattattc aatgctttca tatctatagc ttttatgttt
    13261 ccttctttat ctgccccaat ttttatatca aaaaacatct gatgtctagt attagtcatt
    13321 gcaaaagttt cttctctagt ataaattagt tttgctggtc tttttgtcat ccaagttaca
    13381 aatgatgcat atatctctgt tacagctatg ttttttccac caaaacctcc acctattctt
    13441 ggttttatta ctctaacttt tgaaagaggt attcccagtg ctttagaaac ctgtcttctc
    13501 atatgataag ctgattggtt tgcagaagtt actactaatc tgccattcgt atctatatac
    13561 gtataagctc tatgagtttc catcatacaa tgggcttgtg attgagtcat ataagaatgt
    13621 tctactatta catcactttc tttaaactct ttttctacat cccctttacc cattttttct
    13681 ctcgatacaa tattttttgt agcatccaat ccaaaatcaa atggacaaaa caaatcatct
    13741 tcttcatgga ttaaaatttt atttccttcc gattctcttg catccaatat aggagtcatt
    13801 acttcatatt caacttttat aagtttcata gctttaatag cagccctttc atcttcagcg
    13861 gctattatag caacttcatc tcctacatat ctaactacgt cttcaagtat taattggtca
    13921 tgaggtgatg cttctggata tgactctcca accattgaat atctataatt tggaacatct
    13981 ttgtaagtga atatgtttac tacacctttt acctttaatg cattttttgt atctatgttt
    14041 tttatcttcg caaaagcatg cggacttcta agaagcttaa ttgttaaaac atctttatga
    14101 aaaattaaat cttctgtata tattggtttt ccagtaacaa tggcttcact atctattttt
    14161 cttacctctt tatttaccat cacactcacc tccaatacta ttatacattc tcactactaa
    14221 ggcttttgcc atatcttttc tgtattcttt acttcctctt atattacttc caaatgaaag
    14281 ttcttcactt gatacttcac cagctttttc tatatcattt tctaaactta atatttcact
    14341 tgctttatag gcaatttttg ctcttcttgg tctagcgcct atcgcaattt tataaatact
    14401 tccttctttt aacattgctc catttaatac tgcaaaatca cctgtacatt ttcttataga
    14461 atcaaataca cctatagcat cttttttagg taatataact tctattaata tatctttttc
    14521 aagctcactt tctaaaaaat cagctaagtt cataacccct tttttatata acttaacctt
    14581 tgcatctacc actagtaatg aaggtattaa atctgaaaat ccatacttag caaatacgct
    14641 agctcctact ctggctccac ttctaaattg aactcctact atattagaaa cagcgtttga
    14701 aattacccca ttacagtaat ttttaataac cttatttaat tctaaagttc ttaaacttgt
    14761 gtctgctcca attaatatgc tatcatcagt ttcatttata taatctaaag ctaagtcttt
    14821 taaatctatt gctgagccaa tatttttact acctagtttt aaaaatccac atcctccaag
    14881 tattatgttg ttttttcttg atattagcag ttcataagct tcatctaaac tttttggaac
    14941 tacatattcc tttatagtta tcatactctc tccccatatc aacttaattt tcacttaaaa
    15001 gtctaagtgt ttaaatattt atgtattgct cttaattgac ctttatatcc tgtacatcta
    15061 caaaggttac catttacata atctataact tcttcttctg ttggattttg aagctctctt
    15121 ttcattgcca aaaccatcat tataaatcca ggagcacaaa atccacactg gtcagcccct
    15181 tcgtctgcaa gaaaatctcc aaacttcttt gcttcatcca agaccccctc aagtgttgta
    15241 atatgctgac catctactct agcagtaaga taattacatg aaagcacggc cttgtcattt
    15301 accatcactg tacataaccc acatgagcct gtatcacacc cttttttaac acttacatat
    15361 ccattttctc ttaatgtatc tgctaaaaaa tcatctggtc ttatacttaa ttctttttct
    15421 ttattattta tggtacattt gataatcaaa taaatcacct caaaactcat atttttaagc
    15481 taaagtttta ctatactttt ctatgaataa attacattta ttaataaagg ctattccatt
    15541 tatgaccttc cattctattt tttatagttc ctcttacaca aagtctctca gctgtatctt
    15601 gagcatcttt taatgctttc tcttcattag ctgtcaatat ttttgaatct tccattatta
    15661 tatttccatc tactataaca ctctctatat ttttcatact agaagaatat actaatgtag
    15721 ataccggatt atgcataggt atcgcttttg gtgaaagcat tggattaaat attagtaagt
    15781 ctgctttttt acctatctcc aatgaaccta tctcatcttc cattccaata gctcttgctc
    15841 catctatagt tgccaactca agaacttttt ctgccgacat tgctaatggg tcacacttat
    15901 taactttatg ttgaagtgct gttaatttca taagttcaag catatcttga gagttattac
    15961 tagcggctcc atctactcct aaactaactg ttattccttt tttaagcatt tctggcactg
    16021 gtgcaacacc tgaagataag tacatattac ttgctgtatt atgagacact ttcatatcgt
    16081 attttttagt aagttccata tctttttcag ttagatacac acaatgtacc ataagcacat
    16141 ttggtccaag tattcctaat ttttctaaaa catctatgtc atattgccca tgcaattctt
    16201 ttgctgcttc tctatcaaaa ggagtctctg atatatgtac tgtaaataaa gcatcatcat
    16261 attcttttac cactctccat agcatttcaa gcatttcttg agaatttgac catattgctg
    16321 caggagctac tcctattttg attcttccat tttctgtatt atggtgtttt tcaaacaatc
    16381 ttcttacatc tttttcaacc gtttctacat cttgcattat tccaggatga actccaaatt
    16441 gagctcctgt attcatacat cctcttccaa gtattcctct tattcctaat tctttataag
    16501 catctattat tccatcacaa agacctggct tactatgagg atacatgtag tcaaccatgg
    16561 tcgttatacc acttctaagt ccttcaatac atccaagcat tgcagcatca taagtatctt
    16621 ttggctctaa atagttagct gctggaaatg tcatagtttc taaccagtct ttaagtacca
    16681 tatcatctcc caatcctttt aataaagttt ggaataaatg attatgtgta tttataaaac
    16741 ctgggaataa aactttacct ttagcatcta taattttttt aacatcagta tatttacttt
    16801 ctatctcttt agaatttcca atatcagcaa tcttgttatc ttttactact aatgccccat
    16861 caaaaataac ttctctctct ttattcacag ttactattat ggcattctta ataagtatat
    16921 ccatcattct tatttccccc cgcattattt agtaattttt cttttaatat attgacctgt
    16981 tggatgttct ttaacattac aactttgtac tacatgattt cctctcaaaa atacatcttc
    17041 aactttacat ttaaccttaa atccttcata tggagtataa tctacatttt gtttttgagt
    17101 tttataacta attgtttctt ctttattgat atttaaaatg actatatctg catcacttcc
    17161 tacagctatc tcaccttttt taggatacat tccaaatatt tttgcagcat tcgtagaagt
    17221 aacttccaca aacttattta cacttattct attttctaag accccatatg tatataaaag
    17281 tgctaaccta tgttcaacac caggtgctcc atttggtatc ttactaaaat catcaattcc
    17341 caagtctttt tgccccttaa aattaaatga acagtggtct gtgccaactg tttgaatatc
    17401 tccactagac aatccttccc aaaggtaatt tatgtcttct ttttttctta aaggaggaga
    17461 cattacatac ttagcaccct caaatttatt cttattatat aaattgtctt ctaataatag
    17521 atactgtggg catgtttcta ctatcatatc tatatttttt tctctagcca tttttacagt
    17581 ttcaagtgac tccctacaac ttaagtggac tacataggat tttgaattag ataatttagt
    17641 tatatcagca agtcttgaaa cagactcttt ctcaactatg ttaggtcttg taagtggatg
    17701 atattttggc tctaaattac cattttgtat attttcttct atcaatacat ctagtaaatc
    17761 cccattttca caatgaaatc caactataca acctaaatcc cttgctttct ttaaaaccct
    17821 gtatattgtt ccatcatcta ctttcatgcc atcatatgcc atatacatct taaaagatac
    17881 tatcccatcc gaaataagtt tttccatatg attaaatgta tctttattta aacatgtaat
    17941 tgtcatatga aaaccataat cacaataaca atttccactt gcttttttat gatatgcttc
    18001 tacaccttgc agtaggtttt ccccctcatt ggcttctgca aaatctagta ttgtagtagt
    18061 tcctccagct atagctgctc ttgttcctgt ttcaaaatta tctgcagttg taatagaacc
    18121 tgcattcata tcaaaatgag tatgtgtgtc tattccacca ggaattacaa ttttacctgt
    18181 agcatcaata accttatcac catttatttc taagttattt cctatttcaa ctatcttttc
    18241 atcttctatc cttaaatcac ttatataagt cttatcagag gtaattatag ttccacctct
    18301 tagtattgtt cccatatata cctcctaact tttaagcttt aaagtatttt ctaagtatcg
    18361 taaaacttta tttaaaattg tattttctaa aggtgctata ttcagcacct ctagactata
    18421 tttaaataat ttattgtgaa ctaaatatta ttttccgtat acagatttta atattccata
    18481 gtaaccttct gttcctataa ataactgttc ttgctctata tactcatcta ttgtgtgagc
    18541 aagattttcc ttagaaggac caaatcctat agtttttatt ccagcttcac ctgcatagtg
    18601 acttccattc gtacagaatg agtattgagt tatttctgaa tctattccag cttcttttaa
    18661 tcccttatat gctgcttgaa caaattcatc ttcttcgtca tataaccaac ctgggaagaa
    18721 tctttcactt tctatagtat ttcctgtata gcaatcagct ttttcaaccg cataagaaac
    18781 tttcgcattt aattctgggt cttctttcat catttcatct aataaagctt gtattggagc
    18841 taatacgcct tctcttgttt ctccaactaa taatcttcta tcaaaagtag ctttgcaata
    18901 atctggcact actgatgccc ctggatatgg agaagatttt atatctgtta aaactaatat
    18961 tccatcacct aaaactggat gagttggagg tactaattgt tgtatctttt ggattacatt
    19021 agccatttta taaactgcat ttacaccttt ttctggatta gcagagtgag ctggtttacc
    19081 aaaagtttct actactattt ctcctctacc tctctgacca atctttaagt ttaactctga
    19141 agactcacct attacaacat agtcaggttg aacagcctta cttatctctc tagccgaaac
    19201 accttcaaat atttcttcat gaacaacacc tgctacatat agttctccag caaaatctcg
    19261 attagtgtct ttagcaaaat acgctacagc agacatcatt gcagtatatt gacctttcat
    19321 gtcagaagtt cctctaccat atatctttcc atcaactatt tttccttcaa aaggaggaac
    19381 actccattta cttgcatctg gaactggaac tgtatctata tgtccatcaa ataatatttt
    19441 cttacctggc ttgttacctt ttatacatcc tactatattt ccatatctat ctcttgacca
    19501 actatcaaaa cctaattttt caaaagactc ttctattgct tttacaacac cttcttcatt
    19561 tccagaagaa ctaggatttt gaattaattt ttggcatatt tcagttactt cttgttttct
    19621 ttgttcgttt aacatttcat tatcccccta gattttttat aatgtatgta ttttatatac
    19681 ttatatattt tctaaatttt agaacttata tatcttctaa atatgtaaac caatatctaa
    19741 taattgcatt ttagtaattc cttatatact tggatattct ccatcccaaa ctatacttct
    19801 atatttgtca gggtcagtat ctccttctgt gcttattaaa agtattcttg aattttcatc
    19861 taattttaaa tcttttctta aatctgctaa atcttctctt tccatagctg ctactaaaag
    19921 accagttgta actgctccag attctccaga aattaccttt tcatcaccat ttaaaggatt
    19981 acctaatgtt ctcatacctt tagcagaaac ccagtctggt gctgaaacaa atgctgcagc
    20041 atgatttttt aatacttcaa atcctatagt atttggttct ccacaagcaa gaccagccat
    20101 tatagttggc atatctcctc caacaaatct tggttttcca tctcctgctt ctgctgattt
    20161 atagtagcaa tcagcttcat cagcttctac tactactgtt attgggcatt catcgtatat
    20221 tgaagcaaca tatccttgaa ctgctccagc aagtgaacca acccctgctt gcacaaatac
    20281 atgtgttggt ctatctactc catattcttt taattgctct atcgcttctt gagccatagt
    20341 tccatatcct tgcattatcc atgctggaat ttcttcatat ccatcccatg ctgtatcttg
    20401 aaccattact ccatgatcat cagcttctgc ataatcatta gctaatctta ctgcatcatc
    20461 atagtttaag tctgttatac tagcatctgc tccttctcct ttaattttat ttaatctaaa
    20521 ctcagaagaa ccttttggca ttaatacaac agatttttga cctaatttat tagctgtcca
    20581 agcaactcct ctaccgtgat ttccatctgt agctgtaaag aaagttattt ctcctaattt
    20641 ttcttttatt tctttcgaag ttaatttgtc ataccctaac tcagatatat ctgtatctaa
    20701 tctttgagct aagtatctac ccatagaata agaaccacct aatactttaa atgcatttaa
    20761 tccaaatcta taagattcat cttttacata tactcctgca acacctaatt tttttgctaa
    20821 accttctagg tttgctaatg gagtttcttt atattgagga aagcttttgt gaaaatttct
    20881 aaccttagtt atttcttctt catttaaaaa tttgatacaa ttttccttat caccctttgg
    20941 caaattattt actttccatt taatttcttt taacatctaa aatacctcca aattattgtt
    21001 aaatttttat actttaatat ataagcaatt aacatgccaa cactaaatat atactagata
    21061 tttttctatg actctttagt atagaaattg caatgctttt attattcttt cttttctatc
    21121 tttagttcat acaatgtatg tagaatttaa taactaaaaa accttttcta tcttctcact
    21181 ttttaattct catttttaaa atttaaaaat aaatctcaaa acactttgtt tctatatttt
    21241 ttaatataaa atttataaaa tctaaattaa aacataaaat agtgatgcaa taatctatta
    21301 catcactatt tgtatatatt taataatata ataaatcttt agtggtctct aagaggtgat
    21361 ttttcatctt ttttaacatc taattcttct tttacgacat tccatttttc aagaccaaac
    21421 ttagaaacca taactgcctc tgcagcacct tttccaagtc tttttactgt gtccatacct
    21481 gtctcatcct cttgggcacc ttttgctttt ccatctttac tccatattgt accacctata
    21541 tagcatccac ctaaacctcc agatactaac atttcatgca ttaggaagaa atttattata
    21601 ggaagttttg tcaattcttg gccaccatat ctagttccac cagtagttat agctgcacca
    21661 accttatttt gaagttttcc tggatgaact aaatacattg gacgaagtct attaaatact
    21721 gctgtaagtt gagcagttat attcatatca taaactggag aacctactat aattccatct
    21781 gcctccaata ttttttgctc taattcttgg atatcatctt ttataataca catagtttct
    21841 tttcttatac atgcatcaca atgtacacaa ggacttattt ttttccctct aactgaccaa
    21901 tactcagttt ctataccagg tatagtttct gcttctttca aagcttctaa cactgcatat
    21961 tctgttgctc ctttacgtgg acttccacaa atacctaata tctttgccat aataatatct
    22021 cctcaccaaa taaatctatt tttattatct atttacaaat acaataaatt gttgtttgtg
    22081 ctttaatttc tactatttta attttattgg caatgaatgt atttctacat cagttgcatt
    22141 atatactgca tttgcaacag ctggcgcaac tggtacaaca gcacattctc caatactctt
    22201 accaccaaaa ggtccagctt tttcataact atttacaaat gcaacttgac attttggcat
    22261 atctacagtt ctaaataatt tatatgtttt aaaatcagta gctttaggtc taccttgttc
    22321 atcaaatgcc aattcttcac tcaatgcgta tcctagaccc atatgaatcc caccttctaa
    22381 ttgaccttct aaatttaaag gatttataac tctaccaaca tcatgtacag ctacaaaatc
    22441 aactactttt atatccttag tttctttatc tactaaaact tcagcaaaat gtacaccata
    22501 agaagtaagt ccagctggtg aagaataatc ttcaacaaca gttaactctc ttaatgattt
    22561 actttgacta tatactgcga catcagaaag tgatgctttt acattttcat caagtttact
    22621 aattacatat ccattgtcta gatataaatc ttcttttgat gtttcaagta atttttctgc
    22681 ttcttctact ataaggtttt tcaatttctc tgctgtcttt ttagctcctc caccttctac
    22741 aaatacccct ctacttgcat agtcaccaag gttgaatgta catgcatccg tatcagtttc
    22801 aaatgtatca actttatcag gtgttattcc taaaacttca gctaccatca ttgtttgcat
    22861 agttacgaca ccattaccca tatcatgtgc tcctgttagt agtgtcaatg taccatcttc
    22921 atttaattta agagtcaatg taacaacatc tctatgtgca ccaaaaactc cattaccatg
    22981 tgcacctatt gccataccta tacctcttaa atattttcct tcttcttttg gaagtttttt
    23041 cttttcatcc cacttaaaca tcttcttacc ttgctctata caatccaata ctctaggatt
    23101 tccaagagaa ccgcggaaga ttatatcgac atcatctggc tctactgcat ttttattttg
    23161 aaaatcgact aaatccatac ctatttcctt ggctattttc gcaaattgag cctgttgagc
    23221 cataaatatt tgaggtgacc catagcctct catagctcct gctattggtg tatttgtata
    23281 tacaggcatc ccagtaaact ttatatttgg tattttataa actttaaata ctttatgact
    23341 aagtgctcct ataacattta aagcacttga tgcatatgct cctgtatttg tatatatttt
    23401 tatatcttgt gctattactt caccatcttt atttacacca gtttttaatt ttacaaaaga
    23461 cccatgacga gttcttgttg atatcataga ttcctttctt gtaagaacca ttttaactgg
    23521 tcttcttgtc atttttgata atgcggctgc tactggttca attgtaagtt ctaattttcc
    23581 accaaatgag cctccaatag caggtcttat aactcttact ttatttaatg acatcccaaa
    23641 aatttgagat agtattattc taaatccaaa tgtattttgg caaggtgtat gtacagttaa
    23701 tttatcatta taatcatagt gtgcaattac actatgagtc tctattgcac tatgatgtat
    23761 tgctggagta gagtattcat cttcaaatat atagtcacat tccttgaagc ctttttctac
    23821 atctccccca tttatgttgt tttgagaaac tatatttgaa tctccatgta tgcagatagc
    23881 atcttctttt attgcatctt gtatagtaaa tacagctggc aattcttcat attcaacttt
    23941 tataagtttt acagctttct ctgctatttc tggagtctct gcagctactg ctgcaacacg
    24001 gtcaccaaca aatctaactg tatctgaaaa tataacttca ttttcaggta tattgtgctc
    24061 ataaaatctt aatgaaccat tgtattttct ttgtgatgta ttgagataag tagctatagc
    24121 tctaacacct actactttct cagcttcact tgtatctata ctttttattt ttgcatgtgc
    24181 tacaggactt aaaagcatct tagcgtaaag tacattttgt ggtttcatat cagccacgta
    24241 tttcatttga ccagtaactt ttaaagctgc atcttttaga gggtatgatt ttcctattac
    24301 cttttccata attatctacc ccctaatcta gctgcagata attttacagc ttctataatc
    24361 tttacatatc ctgtgcatct acagagattt tctttaaaag cttctttaat ttcatcttca
    24421 ttaggagatg catttctatt taaaagagct tgtgttgtta taatcatacc aggagtacaa
    24481 tatccacatt gtacagctcc aacttctata aaagcttctt gtattggatg aagattttct
    24541 ccattagcaa aactttctat agtgtatata actttacctt cgcagttttt tgcaagaagt
    24601 ttacaagatt tcatgtcaac tccatctatc aaaactttac atgctccaca actgccacta
    24661 ttacaacctt gtttcgctcc agttagattt aatttttcac gaagtacatg caaaagagtt
    24721 tcattctttt caacttctat ttcatacatg taatcattaa tatttaattt tattttttcc
    24781 attttctcct cctacagata aactaatgtt gtaatagaat attattacaa tcttatttta
    24841 atattagtat aagctattcc acttatgtcc ttccattcta ttagttacat tagctctctt
    24901 acataattct tctgctgcaa gttgtgcatt aagcaacact tgttcttcac tttcaattgt
    24961 agttactttt ccattttcaa gtattacatt tccatcaact aaaacactct ctacattgtg
    25021 catactagct gagtatacca aagttgatac aggattgtga agaggtattg attttggaga
    25081 aagcattgag ttaaatatta ctaggtcagc ttttttccca atctccaaag aacctatttc
    25141 atcttccatt ctaagagttc ttgctccctc aattgtagcc atttcaagaa ctttctctgc
    25201 agaaattgcc agagggtcac aattatttac tttgtgttgt aaagctgtta atttcataag
    25261 ctctaccata tcttgtgcgt tattacttgc tgcaccgtca agacctaaac tcacatttat
    25321 accttttttt aacatttctg gcacaggtgc aacaccagaa gcaagataca tattacttgc
    25381 tacattatga gaaactttta tgtcatactt tttaagcatt tccatgtctt catcagttat
    25441 acatacacaa tgtactgcta caacttctgg acctactata ccccattttt caagtaattt
    25501 tatatctatt tctccatgta tatcctttgt tgctgttctt gcaaattctg tttcagatat
    25561 atgaactgta aaatatgaat catattcttt aactatattc caaagcatct tacccatttc
    25621 ttcagatata gcccacattg aagaaggagc tacacagatt tttattcttc cattttctga
    25681 attatgatat ttttcgaata cccttctcaa atctttttca accgtttcca catcttctat
    25741 aagctctttg tgaataccta aatctataca acctctacct acaacccctc ttatacctaa
    25801 atctttatat gcctttacta ttccatctgt aagtcctggt ctattgtgag tatgcatata
    25861 atcaaccatt gtagttatac cactttttaa accttccata catccaagca ttgcagcatc
    25921 ataagtatct tgttctgtta agaattttgc tgatggaaac atcattgtat ttaaccactc
    25981 atgaagtgcc atatcatcac ctaaaccttt taataacact tggaacaggt gattatgagt
    26041 atttataaag ccagggaata ttacttttcc attagcatct ataacttttt tagcatcaag
    26101 atacttaggc tcaatatcaa ctgtatttcc tatatccaag attctgtcac cttgaatagc
    26161 tattgctcca tcaaatataa catctctgtc tttattaact gtaacaatta ttgcattttt
    26221 tattagtata tcaatcatct taaatccccc tttgaatact ttcattacaa cattttacca
    26281 tatggttttc tcatattata tctaatacat ttatccaata ttttcctcaa gatttgaagt
    26341 aacgttttca gcacttttac gtgactttaa tttaaataat gtttgaagta atatagctat
    26401 tattgctcca gaaactatac ttgaccctcc aaggacagtt ccaattgttt ctgggaattg
    26461 gtctaaaact tgtggagcag ttgtaagacc catacttgtt gctatagata cacctgctat
    26521 aagattgttt tcttcagtga atccatccat actcataata gagaaaccag acattgctat
    26581 tgatgagaaa actactaaag ttgctccacc aacaacacaa gatggtatag ttgtcattat
    26641 tgcacccaat gctggagata tccctgctag taataataca agtgccccta gtgctattac
    26701 aaatctactt gtaactttgt tcatagatac aattactgta ttttggctaa atactccagt
    26761 tggaagagct gcaaatagtg atgaaattat agaagttata gaatttccta aaacaactga
    26821 tgctaattct tcgtcagtta cctctctatc cattgctcct actgtagcta ttgtacaggc
    26881 acccatcata tcagctatac ctattatgta aataatagta aacattacta ttaactctgg
    26941 tctaaattct aatccaaaag ctgctggtgt tggtaaagat actatagctg ctccttgaac
    27001 ggctgagaaa tcaaccaatc ctaaaactaa agatatagca taacctacta atattcctat
    27061 taatattgaa gaatttttta ctaaaccttt accgtattta tttatcatta ttattacaaa
    27121 agcaactata actcctactg tgaagtttat tgggcttcca aatgtttgtg tgccttctcc
    27181 tccagctaaa ttctttatag ctgttgcgaa tagtccaagt cccatacatg ctattatagt
    27241 tccagaaact attggagtga atatatgtct aattttctta actccaaatc ctacaaagaa
    27301 tacgattacc ccagcagcaa tctgtgctcc aaatagagct gctaaaccat ctttagctgc
    27361 tactgaaaga caagctccta aaaatacata actcattccc atcattacag gtaatcttga
    27421 acctaactta aatcctttaa ataaaggtat tggatataac tgtaaaaacg ttgctaaacc
    27481 tgctgctaac atagaaccct gaatcaacat tgttgcttgc ccctggttaa gtcctaccac
    27541 gtttgctatt aatatcgcag gtaccatatt tcctactatc attgctaaca gatgttgtaa
    27601 ggccaaaggt attgattcct ttagtggtgg tatcccatcg acatcatatt ttgaagtatt
    27661 acgtgttttc ataaaataaa tcctcccata cataaatatc ttgactaaat atttttataa
    27721 ttattttcta taaatatttt tatgaccatg aatttattgc tcaaccgata aacacagcta
    27781 aactgagcta tttttataaa aaattaacaa atttctaaat attccctccc cgattttcaa
    27841 cttaaatgaa acattaattg cctggtatat atttatttgt taaatttttt attaaaatga
    27901 atagctatca aaaataatct aacaatctca tactaaataa tttaaacaat tcttttaaat
    27961 tattatatct taattagtct cttccataac agctctttct ttagcctcat cctctagact
    28021 tttatttggt attattagat ttaaaacgaa tgcaaccaat gttgcaatta ctattggaga
    28081 ttctccaaat actaacttta caaatgaagg aaatgcctct tgggctgctg gtactgatgt
    28141 tattcccatg cctaaggcaa ttgccaaacc aacaatggta atatttcttg atgacaactc
    28201 ttctgtaata attaacttta tacctgtcat tgttatcata ctaaatatag atattgtagc
    28261 tcctcctaaa acagaatatg gtatagtagt cattaatgca ccaaatttag gcacaaaccc
    28321 cgacaataac ataaatatac cagctattcc aagcacaaat ctacttatta ctttgttcat
    28381 agctaccatc cccacgtttt ggctatatga tgatggtggt aaacctccaa acaaagctcc
    28441 tatcatagta caaattccac ttcctattac tccacttgat aattccttat ctgtgatatt
    28501 cctatccatg cctcccattg tagtagctga taaatctcca attgcttgaa cagcattgat
    28561 tatacttaca attactactg agattattac aggcatatca aattccatcc caaattcaag
    28621 cggtttaggt atcgcaaacc aagttgcctc tctaataggg tcaaaattta ttatacccag
    28681 aactaaagat acacaatatc caactataat tcccaaaaat attgctgcca attttgcata
    28741 tccttttgca aattgactaa gacctataac taccactaat gttatagccg ctactgccca
    28801 gttttgcata gaggcataag taggactatt tacaccacct gccatataat ttattgctat
    28861 aggatacaaa gataatccaa ttgtaaaaac cactgttcct gcaactatat tcggaaaaaa
    28921 ttttcttatc ttttttatga atatccctat taatactgta gccactcccc ctattaattg
    28981 tgcacccaaa atgcttgcta atccataatt tcctccgact gctacaagtg ttggtacata
    29041 agtaaaacca actccaaaaa ttataggcaa tcttgaacca atatttccta ttggatatag
    29101 ttgtataagt gttgatatac cagctattat taatgcatat tgcactaaaa gtgttatttg
    29161 tgtagggcta acacccacag ctcctcctac gactataggt actgtaacag ttccaactat
    29221 cattgctagt atatgttgca ttgatagtgg caaacacttt aaaattggtg gccttccatc
    29281 aatatcaaac atagaaacat tcttttgata tttactcaag gttatcactc ccaactattt
    29341 tttaatgaca gttattatta tctcacacaa catcctttct ttttttattt tgtcatctca
    29401 atttaatatg aagcaattat aatgccaatt ttttaacata attgttttac atatataatt
    29461 tttattatat ttgttagtat ttgataattt attaaagcat ttattttttt aaattctttt
    29521 aaattttttt tatttttgga taataaaatg ctattacaca aaaaaacact tagaaaatag
    29581 ttttccaagt gttttttatc aattttataa tttcaaattt tagaattgag aataaaaaac
    29641 ctaattatta tacatctatt tttctgtaca atgtagctag tgatattcca agttttttgg
    29701 cagccagttt tttagactta gtatcatttc cgtaaaactt taacactttc tttatatagg
    29761 ctctttcaaa ctcttcaagt gtaagtatgt cttgttccat acttatctca tagtcacttt
    29821 cctcaagtaa ctttatattt atattattta acttaaaata ttcaagtatc tttctattta
    29881 ttattccttt atgtattatt ccatcttcct caagaaggtt taatgccagt tctatagtat
    29941 tttccaactc tctaatattt cctggccaag gatacttaag caacatttgt tccacatctg
    30001 gttctatatg gtacacgttt ttcttcattt ttctcgaata tttgtctata aaattattta
    30061 ttaatatttg tatatcgtct cctctttctc taagtggagg cacttctaaa ggtattacat
    30121 tcaatctata gtataagtct tctctaaatt tattttcctt aaccaactca aataaatctc
    30181 tattagtagc tgatatgatt ctaacatcta tatcaattag ttcatttgaa cctattctcg
    30241 taaacttctt ttcctgtaat accctcaata actttgattg tagttgaatt ggcatatctc
    30301 ctatctcatc taaaaataca acccctccat tggccaattc aaacttacca attttacctt
    30361 ttgaatctgc tccactaaaa gctccttttg tatatccaaa aagttcactt tctagtaaag
    30421 gttctggtat agcagcacag tttatagcaa cgaatgtttt attccctctg tttcctgcga
    30481 gatgaatggc tcttgctatt aattcttttc cagtgccact ttctccagtt atagctacag
    30541 tagaatcact atttccaatt ttgcaaattc tattcttaag agcacgcatt acatcagact
    30601 ctccaattat ggagtctact gttgttgttc cccaaatatt atatacttcc attccaccat
    30661 acattactga atcactgtgt ttgtccataa aatatcaact ccaaataagt attctatata
    30721 ataatcattc acattatcta tttaattata tcataacaga aaagcttagt tataatttaa
    30781 taatattatt ttaaaacaaa acttaataaa aagtatatct acttagt
//
LOCUS       DAMJYN010000041        30665 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.042, whole genome shotgun sequence.
ACCESSION   DAMJYN010000041 DAMJYN010000000
VERSION     DAMJYN010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 30665)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30665)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30665
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.042"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(99..260)
                     /locus_tag="PC466_002062"
     CDS             complement(99..260)
                     /locus_tag="PC466_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769446.1"
                     /translation="MNNFLLNVIAGVIASLIFCLICKVFLKVKSHSTRGKSKSGWEFD
                     FKIKFHKFK"
     gene            complement(601..1041)
                     /locus_tag="PC466_002063"
     CDS             complement(601..1041)
                     /locus_tag="PC466_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HDF2769447.1"
                     /translation="MSNLSAFLSQNAIKVDNVKYVASNRFLDKEGKPVEWELKVLSSE
                     EDEALRRKCTKRVKVIGNNGKHTGQYTSEIDYNSYVAELCVASTVFPDLKDAELQNSY
                     GVMGEAQLLKTMLTAGEYVNYTVKVNEVNGFDTSFEDKVEEAKN"
     gene            complement(1113..1940)
                     /locus_tag="PC466_002064"
     CDS             complement(1113..1940)
                     /locus_tag="PC466_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769448.1"
                     /translation="MEFESGIKLGKLTLIKYLGRNKHSKKVWLCQCECGNKVERVENN
                     LKQSIKNEKPPHCGCSPNWKGQNKRFKDITGKTFGKLTVLKMSGKDKYSHNLWLCQCE
                     CGNRTITSTSALEQGKAQSCGCIRKEILLERSTTHNKSNDSLYRVYHRMIKRCTNKSN
                     KDYNYYGGRGIEVCNEWLEDFINFYNWSIENGYRKGLTIDRINVNGNYEPSNCRWVTW
                     EVQRNNKRNSIRVNYKGEMITLKQCAENLNVKYLFLYNQLVTKKIPLEEVIKNIGME"
     gene            complement(1999..2469)
                     /locus_tag="PC466_002065"
     CDS             complement(1999..2469)
                     /locus_tag="PC466_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tube protein"
                     /protein_id="HDF2769449.1"
                     /translation="MAQTINAKDTVSAKKAECFITIEGKRYNFMQAIDLEAKMEKNKS
                     EVPILGRTTKGNKTTGSTNTGSATFHYNTSIFRELLYRYKETGEDIYFDIQVTNEDPT
                     SAVGRQTVVLKDCNMDSGIITKFDADGEYLDEDMDFTFEDWELVESFALLNGML"
     gene            complement(2486..3796)
                     /locus_tag="PC466_002066"
     CDS             complement(2486..3796)
                     /locus_tag="PC466_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath family protein"
                     /protein_id="HDF2769450.1"
                     /translation="MALGGGTFVTQNKILPGAYINFISAKRATSSLSDRGIVAMPLEL
                     DWGIDEEAFQVTSDDFEKYSVKYFGYDYTHEKLKGLRDLFKNIRLGYFYKLNKGVKAS
                     CTIATAKYSGIRGNDLKVTVTTNIDDNAKFDVVILLDNKKVDTQIAKVITDLQDNDYI
                     TWKKDATLEASAGLVFTGGTNGEAVTGAEYQAFLDKIESYSFNALGCLATTTEIKSLF
                     VEFTKRMRDKVGAKFQTVLYKKSDADYEGVVSIENKIKDKDLVESSLIYWATGAIAGC
                     DINKSNTNKKYDGEFDVDVNYTQIQLEEALKTGKFIFHKVGDEVHVLEDINTFVSFTD
                     DKNDDFSSNQSVRVLDQIANDIATLFNEKYLGKVPNDKAGRISFWNDVVKHHKELENI
                     RAIEDFKTDDVSVELGNDKKTVIVSDAIKVINAMSKLYMTVSVN"
     gene            complement(3797..3973)
                     /locus_tag="PC466_002067"
     CDS             complement(3797..3973)
                     /locus_tag="PC466_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769451.1"
                     /translation="MSKALSKEDNYKFTKEQIVNSKKYVNRKDLLNAILKENELYSFS
                     EVEDRINKFMKGVS"
     gene            complement(3966..4403)
                     /locus_tag="PC466_002068"
     CDS             complement(3966..4403)
                     /locus_tag="PC466_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769452.1"
                     /translation="MLNNIIDGISVKLDKSFGEKYTIYSEDVEQGINEPCFFIVPLNP
                     SKTPYPSGRELKKNSFDVHYFPRSEDKNFEINEIAEMLLEELEYIEIDGDLVRGTNMN
                     FEIIDNVLHFFVDYNYFTIKNNDTNKMDTVELFGGLKRGDNFE"
     gene            complement(4752..5558)
                     /locus_tag="PC466_002069"
     CDS             complement(4752..5558)
                     /locus_tag="PC466_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769453.1"
                     /translation="MAKFLDITGKKFGRLRVIKFSKEIKSGKRNRKYWLCKCDCGNFK
                     EIRTDSLTSGLVQSCGCLKKEQDKLNLTDKYQFKKKYKVQNKRLYSIWKGIISRCTDK
                     NNKRYNRYGERNIIVCDEWFCYDNFANWALSNGYSEKLTIDRINNEGNYESSNCRWVD
                     IKTQCRNRSTNILVKHEEKEITLIELSEKTGISYSCLRSRYSKGLVGNKLIEKVKIIE
                     ESRAKLSIEDVKEIRKKYSDGYTIKQLSEIYPVTYSSISNIVHRRTWKNI"
     gene            complement(5668..5958)
                     /locus_tag="PC466_002070"
     CDS             complement(5668..5958)
                     /locus_tag="PC466_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HDF2769454.1"
                     /translation="MARWGSVDFREFKRVCKKMEKFTKIDLDKFCKDAARELAARLLG
                     KVIRRTPVDTGFLREGWSGVAYARSLPVYKQGNNYIIEVVNPTEYALTQWGI"
     gene            complement(5958..6305)
                     /locus_tag="PC466_002071"
     CDS             complement(5958..6305)
                     /locus_tag="PC466_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769455.1"
                     /translation="MVSKTRKAIEMLYRDKCTIVEYQPIKDPVTKRTNNKEVIVLENQ
                     PCKLSYKNIVSATEGKLAKLEQTIKLFISPDIEIKAGSKLIINDKEYVRSGESAIYPN
                     HQEIILELFKDKA"
     gene            complement(6299..6700)
                     /locus_tag="PC466_002072"
     CDS             complement(6299..6700)
                     /locus_tag="PC466_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769456.1"
                     /translation="MENNIIDEIEKRLESFGYILKDGDKWLIGFVREKIENIIKLDCN
                     IKTMPIELKEIEVDMIVGEFLFTKKNMGQLDIESINFEAVEKSISEGDTKVDFAIGSG
                     SQTPEQRFDSLIAYLTTYGKNKILTFRCLRW"
     gene            complement(6710..6943)
                     /locus_tag="PC466_002073"
     CDS             complement(6710..6943)
                     /locus_tag="PC466_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769457.1"
                     /translation="MPQVKKLNRILTIEECKIDDFLEMGYDLIDETGKAVKYGKSLSV
                     KDLIAENNILRSKVESLEEENKQLKEKNKLTKK"
     gene            complement(6962..7852)
                     /locus_tag="PC466_002074"
     CDS             complement(6962..7852)
                     /locus_tag="PC466_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsid protein"
                     /protein_id="HDF2769458.1"
                     /translation="MAALNYAKEYSNVLAQAYPYTLNFGDLYATENNGRYRWTGSKTI
                     EIPTISTTGRVDSNRDTIAVAQRNYDNAWEPKVLTNQRKWSTLVHPADINQTNYVASI
                     GNITKVYNEEQKFPEMDAYCISKIYADWTALGNTADTTVLTTANVLEVFDKLMEKMTE
                     ARVPENGRILYVTPVVNTLIKNAKEIQRTVNIKDGGTSLNRQTTDIDTVKIIKVPSNL
                     MKTAYDFTTGWKVGAGAKQIFMSLVHPSAIITPVSYQFSKLDEPTAVTEGKYFYFEES
                     FEDVFILNKKADAIQFVVEA"
     gene            complement(7864..8427)
                     /locus_tag="PC466_002075"
     CDS             complement(7864..8427)
                     /locus_tag="PC466_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage scaffolding protein"
                     /protein_id="HDF2769459.1"
                     /translation="MDWLKELLEGIKVEDNKIDVASLQKSIEKKIKETTVTQEDYVNL
                     ETQLNTANETIKKFEGGMTKEDVENLKTTYETDKKTLEETYKKEIEEKDFNYWLGDAF
                     KSVKCRDEIALKAHLDMEALRNSKDRQKAFEEQINPLKQDKDYLFNATLEGEEPKIDT
                     ITPGQEPKINDFGFNFTGVRPHENNNK"
     gene            complement(8495..8743)
                     /locus_tag="PC466_002076"
     CDS             complement(8495..8743)
                     /locus_tag="PC466_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769460.1"
                     /translation="MDNKFKNLQHLIDSIDLGLDIEFDLYNKPYNISIGDDDTRFITL
                     CPNGDTKYYKNGKDMVDNYNIDGKLLKDLWKDIQIVNM"
     gene            complement(8745..10280)
                     /locus_tag="PC466_002077"
     CDS             complement(8745..10280)
                     /locus_tag="PC466_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HDF2769461.1"
                     /translation="MKHKDYWRKRFEQLEEVQNNKSVKYYLELEKKYKLAMNSIEKDI
                     LSWYNRFAENEGISLLEAKKLLNTRELEEFKWNVEEYIKYGKENAINQKWMKELENAS
                     ARLHITRLEALKLQIQQHVEVLYGNELDGIDKLMRDIYTSGYYHTAFNVQQGVNVGWS
                     LMSLDTNRINKIISKPWATDGLNFSERIWGKHRPTLINELHTKLTQSIIRGENPKNLV
                     NDFAKRFNVSKSQAKNLIMTESAFFASASRKDCFSDLDVEKYEIIATLDLRTSNICRE
                     LDGKIFDMKDYQVGITAPPFHCRCRTTTAPWFEDEEGYRAARGEDGKTYYVPSSMKYN
                     EWYEKHIEGRLGKEKADTLRKMQLNESKDRKQFEEYKKVLGNEIPSKFDEYQHMKYND
                     TIRYEEAKKLYKDVNWQVKNQRNLTSGSVHSVPFESKPNSVFDNYKDGKLIQRRYYGN
                     TGKPRLDLDLTDHRNPKQHKIVPHKHDWLADENNHDKVKREKDMELTKAHKIANKDIL
                     NGE"
     gene            complement(10270..11712)
                     /locus_tag="PC466_002078"
     CDS             complement(10270..11712)
                     /locus_tag="PC466_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HDF2769462.1"
                     /translation="MLNIYISETDLIKVQLKKESTFNLVKVIEHYILKHRPEKYKQGE
                     EYYYGNTDVNNKRRYYLLDGAKVDDFTKVNNKAINNYHKLLVDQKVGYSVGNPIVFNA
                     DDDNLTKLLNDLLGEEFDDTITELYLNASNKGVEWLHPYINRKGEFKYVIIPAEEAIP
                     IWDSKRQRELVAFIRFYYIEDIDGNKIKRVEYYTENDVTYFIERGNSFIQEFLYDEYG
                     KMTDIQEGHFRINNKEQGWGKVPFIPFKNNEKCVSDLTFYKSLIDIYDNNISTLADNL
                     DEMQEVIYVLKEYPGTSLQEFIDNIRYYKSIKVDGGGGVDKLEINIPVEAKKELLDRL
                     EKNIIIFGQGVNPESQNTGDKSGVALKFLYSLLDLKCSKTEKKFKKAIRELLWFVCEY
                     LKISGSKSYDYKSVQITFNHSMIINESEKIDMASKSIGIISDETIVSNHPWVEDVNDE
                     LERLKKQEETQKEYDDLIPTNNQEGVIDET"
     gene            complement(11718..12971)
                     /locus_tag="PC466_002079"
     CDS             complement(11718..12971)
                     /locus_tag="PC466_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HDF2769463.1"
                     /translation="MVIEMIVRINFNPDFKEANFTKKRYRAMKGSAGSGKSVNVAQDY
                     ILKLGDKKYQGANLLVVRKSEATHKYSTYAELTGAINRIYGKQADKYWKTTLNPLEIK
                     SKVTGNSIIFRGVNDAKQREKLKSINFSKGKLTWVWCEEATELMESDIDILDDRLRGI
                     LTNPNLYYQMTFTFNPVSATHWIKRKYFDYKNDDIFTHHSTYLQNRFIDEAYYRRMQM
                     RKEQDPEGYKVYGLGEWGETGGAILKNYVIHEFPTEFEYFDNMRLSQDFGFNHANAIL
                     RIGFKDGELYICNEIYVHEMDTSEIIKIANSRGLEKTLFMYCDSAEPDRIKMWKSAGY
                     KAKGVKKGPGSVKAQIDYLKQLRIHVHPSCTNTIKEIQQWKWKQDERTGLYLDEPVEF
                     MDDAMAALRYSIDNKLKNNGISFLK"
     gene            complement(12949..13641)
                     /locus_tag="PC466_002080"
     CDS             complement(12949..13641)
                     /locus_tag="PC466_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2769464.1"
                     /translation="MQDVKEKVKQDYLKGMKQKEISAKYDISLNTLKSWIKRYNWSSE
                     KKKGAPINKRGAPFSNKNSVGYGAPKENKNAEKFGFFSKYLPEETRELIQEISIKDKF
                     DILWEQITIQYAAIIRAQKIMYVKDKEEMIKELKKHEITENSEKIEYEFQFAWDRQAS
                     FLNAQSRAMSELRSLIKQYDEMIHKDWNLATEEQKTRVEKLKCEVANLNKDDIGDDEL
                     KISVDYGDRNDS"
     gene            complement(13711..14220)
                     /locus_tag="PC466_002081"
     CDS             complement(13711..14220)
                     /locus_tag="PC466_002081"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769465.1"
                     /translation="MYKKVLNILLNYYKAINSKEVVELVLTPVLICIISYMFFNSSIN
                     KEVVISLNKDVLTLSGLLVAFGVCIITLLFTTYNKSISEAKDIKTERKVNGFNISYFQ
                     FIQLKAYYTVIMEILVVVICFINTIMLTRYYSNIIFYVLIFFTVHIILSLTTLIISMF
                     HLSWKDRGD"
     gene            complement(14241..15215)
                     /locus_tag="PC466_002082"
     CDS             complement(14241..15215)
                     /locus_tag="PC466_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769466.1"
                     /translation="MSNFKKRYIDVYRIDIINKINGSVYSDEEILKEVIKTFFKDKEY
                     CKENKNGINITKDKKFWITEVKCSEDDLIIKVKLEYTKYNQNTNIINAHTKEVEGNKK
                     MDQGDSNKQHLFIKFMKENNIAVVLFERVFVGVPMIELSKNLHLYYEDMIENNKFDNN
                     MSKTSINITQIASKDFIEQILDLDGVSKITLNVDREKFGTDEDNLFSNLNNSRRHNDL
                     IYKPTFRTRYLPSEVKRCCEKYIKGEEFRNKKINRIIIEGEKNKRKLKLDTEGIKLCR
                     EIEVSLDIDNHIDSEDIFEKMNNLIDDLIENNSVFFNLMYQEVAMSEA"
     gene            complement(15410..15959)
                     /locus_tag="PC466_002083"
                     /pseudo
     CDS             complement(15410..15959)
                     /locus_tag="PC466_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994390.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Bro-N domain-containing protein"
     gene            complement(16242..16721)
                     /locus_tag="PC466_002084"
     CDS             complement(16242..16721)
                     /locus_tag="PC466_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 region 4 domain-containing protein"
                     /protein_id="HDF2769467.1"
                     /translation="MDKESIKEIVRELRKEEREDRKKGVLYNTRLLMKHYNDFKRHID
                     SAVSEAKDVDYLEDDLGKLDNEELYILSIKKSKARTIIMIAHIDSAMKTLKLRQERLH
                     SYEKYRALELYYCDEKTYEEIAEILNCGVVTSRRWINEMVKELGVYLFGIDGLKLTV"
     gene            complement(16714..16851)
                     /locus_tag="PC466_002085"
     CDS             complement(16714..16851)
                     /locus_tag="PC466_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769468.1"
                     /translation="MELISPGKIVRCAWCGRRFYKLDKSKVEYCSRSCSKRARRSDLS
                     G"
     gene            complement(16875..18245)
                     /locus_tag="PC466_002086"
     CDS             complement(16875..18245)
                     /locus_tag="PC466_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HDF2769469.1"
                     /translation="MEFKPHPYQEYTIRKTIDNNNIGLLLDMGLGKTVCTLTAISELM
                     YDYFDISKVLVIAPLRVARDTWSSEVKKWEHLKHLKVSKVLGSKLDRVRALSTDSDIY
                     IINREMVPWIVDFYKRKWPFDMVVIDELSSFKSNKAQRFKSLKKVLPLTKRVVGLTGT
                     PTPNSLIDLWAQMYLLDRGERLGKTITGYKERYFEPGQKNYQTGAIYNWQPKNGAENA
                     IHNKIKDICISLKAEDYLNMPRKIDNKIEIHLDSKILKYYKELEKEKILELDRDIITA
                     SSAAVAANKLLQLANGAIYDNDKNVKELHREKLEALKEIIDVSNGKPIIVFYNYKHDY
                     NRLMKEFKSLKPRTIENSKDIYDWNNGRIQLLLCHPASTGHGLNLQSGGSIIVWFGLT
                     WSLELYQQANARLYRQGQRETVIIHHLICKGTIDEQVMEAIENKDKGQSALLEAVKAK
                     LKEYRE"
     gene            complement(18194..18520)
                     /locus_tag="PC466_002087"
     CDS             complement(18194..18520)
                     /locus_tag="PC466_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VRR-NUC domain-containing protein"
                     /protein_id="HDF2769470.1"
                     /translation="MLESKIEKRLKKEIELLGGKAMKFISPGEAGVPDRIVLLPEGHV
                     IFVELKAPGKKLRKLQQYKMRELRELGFKVKCVSTLKEIDDFIKEVKGWNLNHIHTKN
                     TQLEKL"
     gene            complement(18802..21219)
                     /locus_tag="PC466_002088"
     CDS             complement(18802..21219)
                     /locus_tag="PC466_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769471.1"
                     /translation="MDIKASEIEHINVRHDGQLMLAIGKNKLETHWKNKSILWSELVN
                     RLSKTLRTQETYTEYRKMSKTEKDRVKDVGGFVGGSLKNGRRKAENIANRSIITLDID
                     YANKDIWEDITLLNDYACLMYSTHSHTENNPRYRLVIPLTRPVLPEEYQAISRMIADT
                     IGIDMFDDTTYQPHRLMYFPSTSIDGDYIFKFQDGEFLNPNEILDLYLDWTDVSYWPE
                     SSRERQKFNTQLKKQQDPIEKAGIIGAFCRSYSIKETIENFLNEVYIPGIDETRYTYS
                     EGSTSGGVVIYDDKFSYSHHGTDPASGILCNAFDLVRIHKFGELDEDAKPETPVNRLP
                     SFTRMSEFASSDTKVRKTIGRENLDKAKDDFGDIDFEDDEWLTRLDYDNKGSYKKTTN
                     NILMFIENDPYLKGKIAYNEFSNRAVVLGKLPWRKDDKLNDWNDSDDSGLRHHIETIY
                     NISSPSKVNDALIIAFENNTFHPIKDYLNSLKWDGIKRVDTLLIDYLGAEDNHYTRTI
                     IRKVLVAAVARVFNPGIKFDNMMVLSGPQGMGKSTFIKKLGGDWYSDSLTTVQGKEAY
                     EQLQGVWLLEMGEMMATKKADIEAVKHFLSKSEDIYRVAYGKRTSRFLRQCVVIGTTN
                     DKEFLRDKTGNRRFWPIDTGVKKVNKSIFNGQLDNERNQIWAEAVELCKANEQLYLSD
                     EEKKEAERQQRTHSEENAKSGIIEEYLNKPITENWYDLSISEKREYIHGSDFGDLKEG
                     TILREKTCVMEIWVELFNGEPKQLTPILSREINDILKGLDDWISYNGNLRFGKIYGRQ
                     RAYVRKS"
     gene            complement(21231..23189)
                     /locus_tag="PC466_002089"
     CDS             complement(21231..23189)
                     /locus_tag="PC466_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase"
                     /protein_id="HDF2769472.1"
                     /translation="MRTLSIDIETYSDLDIKKVGVYRYVDSANFEILLFAYAFDNEEV
                     KVIDLVNDEELPKEVIEALNDNKVIKSAFNANFERTAISKFLNINLKPNEWSCTMIKA
                     LTLGLPGSLDSVSKALKFNEDKQKMKEGKALIQYFCKPCKATKVNKGRTRNLPIHDME
                     KWNKFKEYCKQDVVVEREIRNKLSKYKTTEREIKLWYLDQRINDTGIKVDTELIENAI
                     ECDKRYTEKLTKEAIKITGLNNPNSPAQLKKWLSDKVGFEITSLTKESIPEILKQVDD
                     ENVVRILELRKLMSKTSIKKYEAMKLAKGNDNRVRGLLQFYGANRTGRWAGRLVQVQN
                     LPQNHIEDLDLARNLLKEGDFDLIELLYDSVPDVLSQLIRTAFIPSEGHRFIVSDFSA
                     IEARVIAWFAGEKWRLDVFNSHGKIYEASASHMFKVPIESIKKGDPLRQKGKISELAL
                     GYGGSIGALTSMGAIKMGLDEEELQPLVTTWRNANPNITKFWWDVDKAAKKAIKDRTI
                     VKLQHGIKFIYNPGVLFIELPSGRRLSYLRPKIEPHTTFSGDKITYEGMEQTSKQWKR
                     IDTYGPKLVENIVQATARDCLREAMFNVTDAGYSIVMHVHDELVIDVDKKGGSLEEVN
                     SIMGKEISWAKGLPLKADGYECDYYKKD"
     gene            complement(23189..23761)
                     /locus_tag="PC466_002090"
     CDS             complement(23189..23761)
                     /locus_tag="PC466_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2815 family protein"
                     /protein_id="HDF2769473.1"
                     /translation="MSNSVQSTKVVTGKVRLSYCNIFKSRAMVEGAEPKYSVCILIPK
                     SDKVTLGRIKKAIDAAKEQGKTSKWGGKLPGNLKTPLRDGDAERADEAEEYVGMYFLN
                     ANSTQKPGIVDKDLNEILDNTEVYSGCYGRVSINFFPYNSAGNKGIGCGLQNVQKLAD
                     GEVLGGARASAEADFSDDFEYEDEEEDFLS"
     gene            complement(23784..24356)
                     /locus_tag="PC466_002091"
     CDS             complement(23784..24356)
                     /locus_tag="PC466_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase subunit sigma-70"
                     /protein_id="HDF2769474.1"
                     /translation="MSNQEITKLVENNLNLVHFSINRFFKSYVEQHPYLYEEFYQEGC
                     IGLYKAALNYDSNRGKFSTVAVSYIRIEMFKALRYGEKHYRNSIEGLDVSVFEDSKRP
                     LKDIHGFYEIQFNYDVDYIRKIARKSYLKDIDKIVDWILQDKKISDIGELLNVSSTVI
                     CGRIKLFSKQVRDLDKFGEITSNIKSIYQI"
     gene            complement(24409..24744)
                     /locus_tag="PC466_002092"
     CDS             complement(24409..24744)
                     /locus_tag="PC466_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769475.1"
                     /translation="MPLDAGIKDKLDESISIILDLKDRKKSIEKDLDYEKDNLLDMLK
                     RLNITEYNSTEENAKVIVMDFKRESLIKDKVMSTFLEVNDNHLDRVYIPEHIKVSPVC
                     FVSVRAKDN"
     gene            complement(24759..25925)
                     /locus_tag="PC466_002093"
     CDS             complement(24759..25925)
                     /locus_tag="PC466_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2800 domain-containing protein"
                     /protein_id="HDF2769476.1"
                     /translation="MPLQHARLSASGAHRWLHCTPSIKLEENYPPLTSIYAEEGTVAH
                     ELAEVKLMLEYEKISKKAYNARIKKIQKSEYYNSEMEDYIQSYVENVVELVNDSKAIC
                     DDVIVMLEERLDFSEWVPEGFGTGDVVVISDGILQVIDLKYGKGLEVSAIENPQLRLY
                     GLGAYNQFEMLYDIDLIKTTIIQPRLDNISSEEIEVTKLLTWADNVKKKAQMAFNGEG
                     EFVSGSHCGFCRAKNDCRKRAEDNLKLARKYDFADTFALNKYEIADILGFAKNIQDWL
                     KDVQSYALEQAEKHGVKYPGYKLVEGRSNRKYVDEQEVAKVLLNSDYDEEKIYKPRTL
                     KGISDMEKAIGKKSFAKLLSDLIIKPVGKATLVVESDKRSEINSIDSAKKDFEI"
     gene            complement(25937..26374)
                     /locus_tag="PC466_002094"
     CDS             complement(25937..26374)
                     /locus_tag="PC466_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769477.1"
                     /translation="MVEVNVNVKVKVEAPEFTNALLVVANALGGLNLGKAMQIEPINI
                     TDMKEEKKVEVKKAEKIKKVEVKEDVKEEIAEAKEEIEKNNENTTSEVKYTKEEVRTK
                     AAQVSKAGKKDKLKELFGEFGASKLSEVKEEDYSAFMNKLESL"
     gene            complement(26445..26594)
                     /locus_tag="PC466_002095"
     CDS             complement(26445..26594)
                     /locus_tag="PC466_002095"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769478.1"
                     /translation="MKLLSLDTNNKNVVTLKKDGKVIADIVFKDIKTGKKISVGILNK
                     KVLVK"
     gene            complement(26575..26967)
                     /locus_tag="PC466_002096"
     CDS             complement(26575..26967)
                     /locus_tag="PC466_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2769479.1"
                     /translation="MDISESIAKQFSDSLKSLIEIEISKQETDRVKSQTIEQKVKVLE
                     PKDIVVLIKRGYPNYLITVEEARGILKLDTAFMRRLVSTGLIKSLVRGDGRKISRYEV
                     DDFIERNQGKNLDELLKAVEWGDEIAES"
     gene            complement(26998..27195)
                     /locus_tag="PC466_002097"
     CDS             complement(26998..27195)
                     /locus_tag="PC466_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2769480.1"
                     /translation="MLIGDNIKQMLRKRDIKPYKLAKELNIDVSGLYKLLRNKSSNPT
                     IDTLIKLADYLDITLDELVGR"
     gene            27271..27645
                     /locus_tag="PC466_002098"
     CDS             27271..27645
                     /locus_tag="PC466_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769481.1"
                     /translation="MQFSNNISKELQESIRKTVSDTSNTEYFYYAEFQYKIILKSIEE
                     FEKELDDEHEIALKLTNFGKDVLMIVEEVGYHNPCLIHYYGIVNGVYSEILQHTSQIN
                     FMITSVKKTDPSKPARRIGFIL"
     gene            complement(27655..27864)
                     /locus_tag="PC466_002099"
     CDS             complement(27655..27864)
                     /locus_tag="PC466_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769482.1"
                     /translation="MENKKIEEIEKRITMLENQLQAQLFSQITAQSNSDFIDYMYQCI
                     VLYLHEMNKSEKRKISEITKERIRK"
     gene            complement(27911..28720)
                     /locus_tag="PC466_002100"
     CDS             complement(27911..28720)
                     /locus_tag="PC466_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor"
                     /protein_id="HDF2769483.1"
                     /translation="MNNLQIFKNKTFGEIRVIELNGEFWFVGKDIAEQLGYKDTSDAL
                     KRHVDDEDKGVGEIPTPGGNQNMKVINESGLYSLILSSKLPSAKLFKRWVTNEILPSI
                     RSTGTYNMIDLQTKLPTTYKEALQHLIEQVEVNEQLQLESKMKDQVIKELKPKADYTD
                     MILKNKGLVTITQIAKDYGMSGKEMNKILHERGIQYKQSGQWLLYKQHQGKGYTHSET
                     IDITRSNGMPDVKMTTKWTQKGRLFLYDLLKTNNILPDIEKGYSYQTSILG"
     gene            complement(28768..28971)
                     /locus_tag="PC466_002101"
     CDS             complement(28768..28971)
                     /locus_tag="PC466_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2769484.1"
                     /translation="MKKRSLKAGRIEAGYTQEELAYKIGIAKSTYNLKENGKRNFTEK
                     EMIMISYILNKTMDELFLEKRLT"
     gene            29148..29489
                     /locus_tag="PC466_002102"
     CDS             29148..29489
                     /locus_tag="PC466_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HDF2769485.1"
                     /translation="MATFGERFKQLREEKKLTQDELVSKFNKVYFTSFNKSTISQYEN
                     NKRKPEINILENWADFFDVSIDYLLGRTLVRNHIDTVAAHRVNPHKDLPEEAQEQLND
                     YIEFLMNKYKK"
     gene            29501..30049
                     /locus_tag="PC466_002103"
     CDS             29501..30049
                     /locus_tag="PC466_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2769486.1"
                     /translation="MLILKKLRTEKGISLDKLSTDLNINKSTLSRIENGLREPKESFI
                     KDCSDYFGVSTDYLIGKINIDDSNKLTKCLNSTFPIRLKELRKKKELTQAELSKLLNC
                     SLSKIAMLETSKREPVKEDLLRISEFFNVSVDYLLGKTSIENYITTDEISKIIKSYES
                     LPKEAQEHINSYIEFLVDRYKK"
     gene            30125..30631
                     /locus_tag="PC466_002104"
     CDS             30125..30631
                     /locus_tag="PC466_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HDF2769487.1"
                     /translation="MNKLDALLDLANNEEIEIYYTDKIADDIKGLYINRQGLKIISLL
                     NSLKQNNAKLIEILAEELGHHFTSVGNYVSSKNSYKNKILIDKTENKALKWACEFLIT
                     EEEIIHVINSHATSVYEIAEELQVSINFLLKRLEFLSKKKSMLDLGNNRFLVLTNLPN
                     FYIYEDIF"
BASE COUNT         9169 a         5792 c         3096 g        12608 t
ORIGIN      
        1 ataaacaata ttttttctaa tttgtggtat aataaaagca agaagaacta caatctattt
       61 gacagtagag tgaagttcat aatttaaaca attagtaatt atttaaattt gtggaacttg
      121 attttaaaat caaattccca gccactttta ctcttgccac gagttgagtg gctttttact
      181 tttagaaata ctttacaaat taagcaaaat attaaactag caataacgcc agctattaca
      241 ttaagtaaaa agttattcat acttcccacc tcctttcatt aggaagtagg ttttatccca
      301 gtatgaactc cactctataa attgtagatt acatcttctt gctaaaaata ttataacata
      361 taattattac atattttacc tattctatat ttattttttt attttgctat cttcttcgtc
      421 ccctctttct ctctctttca gcttctttca ttgcttcctc ttcatcttct atctttataa
      481 gtattgaggc ggctgctaac gctctctcat taacttctaa attcatatat tcacttggct
      541 tccactttaa tttttgaata caataatgag tgatgctagc atcaaaatcg ccacctctga
      601 ttagtttttt gcttcttcta ctttatcctc aaaagatgta tcaaatccat tgacttcatt
      661 cacttttact gtataattga catactcacc tgctgtaagc attgtcttta ataactgagc
      721 ttctcccatt actccataac tattttggag ttcggcatcc tttaaatctg gaaatactgt
      781 agatgctaca cataattcag ctacataact attgtagtca atttcacttg tatattgtcc
      841 agtatgctta ccattgttac caatcacttt tactctttta gtacactttc ttcttagtgc
      901 ttcgtcttct tcagatgata aaacttttaa ttcccattca actggtttcc cttctttatc
      961 taaaaatctg ttactcgcta catattttac attatcaacc tttattgcat tttgacttaa
     1021 aaaagcactt aaattactca tattattcta atctcctttt attttaattt ttcatataaa
     1081 aaatacacat ttataactta taaatgtgta ttttactcca tacctatatt ttttattact
     1141 tcttccaatg gaattttttt agtaactaat tgattataaa gaaatagata cttaacattc
     1201 aaattttctg cacattgttt taaagtaatc atttcacctt tataattaac tctaatacta
     1261 tttcttttat tatttcgttg aacttcccaa gtaacccatc tacaatttga tggttcgtaa
     1321 tttccattca cattaattct atctattgtt aaaccttttc tatatccatt ttctatagac
     1381 cagttataaa aatttataaa atcctctagc cattcattgc atacttctat gcctctacct
     1441 ccataataat tataatcttt attactctta tttgtgcacc ttttaatcat acggtgataa
     1501 actctatata agctatcatt agatttatta tgcgttgtag agcgctctag taatatttcc
     1561 tttcttatac agccacaact ttgtgctttt ccttgttcta atgcacttgt actagttatt
     1621 gttctatttc cacattcaca ttgacataac cataaattgt gactatattt atctttccca
     1681 gacattttca atactgtaag cttcccaaaa gttttcccag ttatatcttt aaatctctta
     1741 ttttgtcctt tccagtttgg agaacaacca caatgtggag gcttctcatt tttaattgat
     1801 tgctttaaat tattttctac tctctcaact ttattcccac actcacattg acatagccag
     1861 acttttttac tatgtttatt tctccctaaa tatttaatta aagtaagttt gcctaattta
     1921 attccacttt caaattccat gaaatacctc caaataattt atacttacat cataatattt
     1981 ttcaagtata attcaatttt ataacattcc attaagtaat gcaaaggatt caactaattc
     2041 ccaatcctca aaagtgaaat ccatatcttc atctaaatac tcaccatcag catcaaattt
     2101 agtaattatt ccactgtcca tattacaatc tttaagtact actgtctgtc ttcctacagc
     2161 agatgtaggg tcttcatttg taacttgtat gtcaaaataa atatcctcac cagtttcttt
     2221 atatctgtaa agtaattctc taaaaataga agtattataa tgaaatgttg cacttccagt
     2281 atttgtactc ccagttgttt tatttccctt tgttgttctt cctagaattg gaacttcact
     2341 tttatttttt tccattttag cctctaaatc tatagcttgc ataaaattat atcttttacc
     2401 ttctatagtt ataaaacatt cagctttctt tgcactaact gtatctttag catttattgt
     2461 ttgagccata ttatcactct cctctctaat taactgaaac agtcatataa agcttactca
     2521 tagcatttat taccttaata gcatcagata ctatgacagt tttcttatca tttccaagct
     2581 ctacactaac atcatcagtt ttaaaatctt ctattgccct tatattctct aattctttat
     2641 ggtgtttaac aacatcattc cagaaactta ttcttcctgc cttatcattc ggaactttac
     2701 ctaaatactt ttcattaaat aaagttgcaa tatcattagc aatttggtca agtactctaa
     2761 cactttggtt acttgaaaaa tcgtcatttt tatcatctgt aaatgataca aaagtattta
     2821 tatcctctaa cacatgaact tcatctccca ccttgtggaa tataaattta ccagttttta
     2881 aagcttcttc aagttgtatt tgtgtataat taacatcaac atcaaactca ccatcatact
     2941 ttttattagt attagattta tttatatcgc atcctgctat agctccagta gcccaataaa
     3001 tcaagctaga ttcaactaaa tctttatctt taatcttatt ttctatagac actacacctt
     3061 cataatctgc atcacttttc ttatatagta ctgtttgaaa cttagctcct accttatctc
     3121 tcattctctt tgtaaattct acaaataaac ttttaatttc tgttgttgta gccaaacacc
     3181 ctagtgcatt aaatgaataa ctttctattt tatccaagaa agcttggtac tctgctcctg
     3241 tcacagcttc gccattggtt ccaccagtaa atacaagtcc tgcacttgct tctagtgttg
     3301 catccttctt ccaagtgata tagtcattgt cttgtaagtc tgtaataacc tttgctattt
     3361 gagtatctac cttcttatta tctaaaagta ttacaacatc aaacttagca ttatcatcta
     3421 tatttgttgt aactgttact tttaagtcat ttcctcttat accactatat tttgctgtgg
     3481 ctatagtaca actggcttta acgcctttat ttaatttata aaaatatccc aaccttatat
     3541 ttttgaataa atctctcaaa cctttcagct tctcatgagt ataatcatat ccaaaatact
     3601 tcactgaata cttctcaaaa tcatcactgg ttacttggaa tgcttcttca tctatgcccc
     3661 aatctaactc taaaggcatt gcaacaatac ctctatctga taatgaactg gttgccctct
     3721 tagctgagat aaaatttata tatgcaccag gaagtatttt attttgcgtt acgaatgttc
     3781 ctccacctaa agccatctaa ctcactcctt tcataaattt atttattcta tcctctacct
     3841 ctgagaagga atataactca ttttctttta aaattgcatt taataaatct tttctattta
     3901 catacttctt agagttaact atctgctcct tagtaaactt gtagttatct tctttgctta
     3961 atgctttact caaaattatc acctctcttc aaaccaccga ataactctac tgtatccatc
     4021 ttattggtat cattattttt tatagtaaaa tagttataat caacaaagaa gtgaagaaca
     4081 ttgtctataa tttcaaaatt catatttgta cctcttacta aatctccatc aatttctata
     4141 tactctaatt cctccagtag catctcagct atctcattta tttcaaaatt cttatcttct
     4201 gaacgaggga aataatgtac atcaaaagaa tttttcttta attctctccc gcttggatat
     4261 ggtgtcttgc ttggatttaa aggaacaata aaaaaacaag gttcattaat accttgctcc
     4321 acatcttcgc tataaattgt atatttttct ccaaacgatt tatctaactt tactgatatt
     4381 ccatctataa tattattaag catcaaacac tcctttaagc aatattaata gttttttctc
     4441 tattatctta tcaacttgac tttgtagttc catttctgaa atagttaaga aatgttgtcc
     4501 tttaacccaa cccttgccat ttttagttct atgaccaaat tcaacatatg cattttgtta
     4561 tcctaaaggc tttttatcct ctagctctta tagtttccta taagttcggc gtacatcatc
     4621 aacaaaataa actttattta gttgcccagc actcttggag agattatatt tattcactct
     4681 ctacgctcta cggaaaccta tagcctatcc gcaatctata ggttttcctc ggtattggca
     4741 tatataatta attaaatatt tttccatgtt cttctatgga ctatatttga tatagatgaa
     4801 tatgttacag gatatatttc acttagttgt tttattgtat atccatcaga atactttttt
     4861 ctaatttctt ttacatcctc aatagataac ttagctctgc tttcttcaat aatcttaact
     4921 ttttctataa gcttatttcc tactaatccc ttagaatatc tacttcttaa gcaagagtat
     4981 gaaatacctg ttttttcaga aagctctatc aatgtaattt ctttttcttc atgttttact
     5041 aatatatttg ttgacctatt tctacattgt gtctttatat ccacccatct acaattgctt
     5101 gattcataat ttccttcatt atttattcta tcaattgtaa gtttctctga atatccatta
     5161 ctcaatgccc aatttgcaaa attatcatag caaaaccatt catcacacac aattatattc
     5221 ctttcaccat atctattgta tcttttatta tttttatctg tacatctaga tattataccc
     5281 ttccatatac tgtaaagtct tttattttga accttatatt tctttttaaa ttggtatttg
     5341 tctgttaaat ttaatttatc ttgttctttt tttaaacatc cacaagattg cactaagcca
     5401 ctagttaaag agtcagttct tatttctttg aaatttccac aatcacactt acataaccaa
     5461 tatttcctat ttcttttacc gctttttatc tctttagaaa atttaatgac tcttagcctt
     5521 ccaaattttt ttcctgtaat atctaaaaat tttgccataa aatcacctct tttatacatt
     5581 ataaatcaag agttattcta tgtccatatt ctacctactt tataatgtaa cactattaca
     5641 cttagcgttt accgattttg ctgggtttta tatgccccat tgtgttaagg catattcagt
     5701 tggattaaca acttctataa tataattatt accttgtttg taaacaggaa gcgacctagc
     5761 ataagctact ccactccaac cctctctcaa aaatcctgta tcaactggtg tccttctaat
     5821 tacttttcct aagagtcttg ctgctaattc tcttgctgca tccttgcaaa acttatctaa
     5881 atcaatcttt gtaaatttct ccatcttttt acaaactctt ttaaactctc taaaatcaac
     5941 actgccccat ctagccatta tgctttatcc ttaaataact caagtattat ttcttgatga
     6001 tttggatata tagctgattc tccacttctt acatactctt tatcatttat aataagtttt
     6061 gaacctgctt taatttctat atctggagat ataaagagtt taatagtttg ctctagctta
     6121 gctaatttcc cttctgtagc agaaactata tttttatatg aaagtttaca tggttgattt
     6181 tctaatacaa tcacttcttt attgttagtt cgttttgtta cagggtcttt aattggctga
     6241 tactcaacta tagtacattt atctctatat aacatttcta ttgcttttct agttttactt
     6301 accatcttaa gcacctaaag gttaatatct tattcttacc ataagtagta agataagcta
     6361 ttaagctatc aaagcgttgt tctggtgttt gagaaccact tcctatagca aaatctacct
     6421 ttgtatcacc ttctgatata gacttttcta cagcttcaaa gttaatgctt tctatatcta
     6481 attgacccat atttttcttg gtaaataaga actctccaac tatcatatca acttcaattt
     6541 ctttcaattc aattggcata gtttttatat tacaatctag tttaataata ttttctattt
     6601 tttctcttac aaaacctatt aaccacttat ctccatcttt taatatatat ccaaaacttt
     6661 caagtctttt ttctatttca tcaattatat tattttccat aattttcacc tactttttag
     6721 taagtttatt tttctcttta agctgcttat tttcttcttc taaagactca acttttgacc
     6781 ttaaaatatt attttcagct attaaatctt ttacacttaa tgacttgcca tactttactg
     6841 ccttaccagt ttcatctatc aaatcatatc ccatctctaa gaaatcatct attttacatt
     6901 cttctatggt tagtattcta tttagttttt ttacttgtgg cactatatat cactcctttt
     6961 tctatgcttc aacaacaaat tgtattgcat cagctttttt atttaatata aatacatcct
     7021 caaaactttc ttcaaagtag aagtattttc cctctgtaac tgctgttggt tcgtctaact
     7081 tagagaactg ataagaaaca ggtgtaatta ttgcacttgg gtgaactaag gacataaaga
     7141 tttgtttagc tcctgctcct actttccatc cagttgtaaa atcatatgca gttttcatta
     7201 gattagatgg tactttaatt attttaactg tgtcaatatc tgtggtttgt ctatttaaag
     7261 aagttccacc atcttttatg tttactgttc tttgtatctc ttttgcattt ttgataagtg
     7321 tatttactac tggagtaaca tacaatattc ttccattttc aggtactcta gcttctgtca
     7381 ttttttccat taacttatca aatacttcta atacgtttgc tgttgtaaga acagttgtat
     7441 ctgctgtgtt acctaatgcg gtccaatcag catatatttt agatatacag taagcatcca
     7501 tctctggaaa cttttgttcc tcattatata cttttgttat attacctatt gaagccacat
     7561 aattagtttg gtttatatct gctggatgaa ccaatgttga ccatttcctt tgattagtta
     7621 ataccttagg ttcccaagca ttatcatagt ttctttgagc tactgctatt gtatctctgt
     7681 ttgaatctac ccttccagtt gtagatatag ttggtatttc tattgtttta gaacccgtcc
     7741 atctatatct tccattattt tctgttgcat acaaatcccc gaagtttaaa gtataaggat
     7801 atgcttgtgc taaaacattt gaatattctt ttgcataatt tagtgctgcc attttatttc
     7861 ctcctattta ttattatttt catgaggtct taccccagta aaattaaaac caaaatcatt
     7921 tatcttaggc tcttgccctg gtgttatagt atctatttta ggttcttcac cttctagtgt
     7981 tgcattaaac aaataatctt tatcctgttt caaagggttt atttgctctt caaaagcttt
     8041 ttgtctatct ttactatttc ttagggcttc catgtctaaa tgagctttta acgctatttc
     8101 atctctacat ttaacagatt taaaagcatc acctaaccag taattaaaat ctttttcttc
     8161 aatttctttt ttgtaggttt cttccaaagt tttcttatca gtttcataag ttgtttttag
     8221 attctctaca tcttcttttg tcatacctcc ttcaaacttt ttaatagttt cattagctgt
     8281 attaagttgt gtttcaagat ttacataatc ttcttgagta actgtagtct cctttatttt
     8341 cttttctata gatttttgaa gagaagctac atcaattttg ttatcctcta cttttattcc
     8401 ttctagcaat tcttttaacc aatccatttt aaatttctcc tttcattttt tacaaaataa
     8461 aagcacctac taatttatta tttagcaagt gcttttacat atttactatt tgtatatctt
     8521 tccataaatc ctttagtaat ttaccatcaa tgttgtaatt atcaaccata tccttaccat
     8581 ttttataata ctttgtatct ccattagggc aaagagtaat aaaccttgta tcatcatctc
     8641 caatagatat attatatggt ttattatata agtcaaattc tatatctaat cctaaatcaa
     8701 tagaatcaat taaatgttgt aaattcttaa atttattatc cattttattc tccattcaaa
     8761 atatctttgt tagctatttt atgagctttt gtaagctcca tatccttctc tctttttacc
     8821 ttatcatggt tattttcatc agctaaccaa tcatgtttat gaggtacaat tttatgttgc
     8881 tttgggtttc tatggtcagt taagtctaaa tctaatctag gttttcctgt attaccatag
     8941 tatcttcttt gaattaattt accatctttg taattatcaa atacactatt tggttttgat
     9001 tcaaatggca ctgaatgaac acttccacta gttaaatttc tctgattctt aacttgccaa
     9061 tttacatcct tataaagctt tttagcttcc tcatacctta tagtatcatt atacttcata
     9121 tgttgatatt catcaaattt agaaggtatt tcatttccta ataccttttt atattcttca
     9181 aattgttttc tatctttact ctcatttagt tgcatttttc taagggtgtc agctttttct
     9241 tttccaagtc taccctctat atgtttctca taccactcat tatacttcat actagatggt
     9301 acataatatg tttttccatc ttctcctctt gctgctctat agccttcttc atcctcgaac
     9361 caaggagctg ttgttgtcct acaacgacaa tgaaatggtg gagctgttat tccaacttga
     9421 taatctttca tatcaaatat ttttccatct aactctctgc atatatttga agttcttaaa
     9481 tctaatgtag caataatctc atatttctct acatctaaat cactaaaaca atcttttcta
     9541 cttgctgatg caaagaaagc tgattcagtc attatcaaat tcttagcttg tgatttagat
     9601 acattaaatc tcttagcaaa gtcatttact agattttttg gattttcacc tctaataatt
     9661 gattgagtta gcttagtatg tagttcattt attaaagtag gtctatgctt accccaaatt
     9721 ctttcactaa agtttaatcc atctgttgcc catggtttag agataatttt atttattcta
     9781 ttagtatcaa gactcattaa actccaacca acgtttactc cttgttgaac attaaaagct
     9841 gtatgatagt atccacttgt ataaatatct ctcattagtt tatcaatacc atcaagttca
     9901 tttccatata aaacttctac gtgttgctgt atttgtaact ttaaagcttc aagccttgtt
     9961 atatgaagtc ttgcactagc attttctaac tccttcatcc acttttgatt tatagcattt
    10021 tctttgccat atttaatata ctcttctaca ttccacttaa attcttctaa ttctcttgta
    10081 tttaacagtt tcttagcttc taataaagat attccttcat tttcagcaaa tctgttatac
    10141 catgataata tatctttttc tatactattc atagctaatt tgtatttctt ttccaattca
    10201 agataatatt ttacactttt attgttttga acttcttcta attgttcaaa tcttttcctc
    10261 caataatctt tatgtttcat ctataacacc ctcttgatta ttagtaggaa ttaaatcatc
    10321 atattctttt tgggtttctt cctgtttttt aagtctttca agttcgtcat taacatcttc
    10381 aacccaagga tgattactaa caatagtttc atctgatata attccaattg atttagaagc
    10441 catatctatt ttttcagact catttattat catagaatga ttaaatgtta tttgaactga
    10501 cttataatca tagctcttac taccacttat ctttaaatac tcacacacaa accataaaag
    10561 ctctctaatt gcttttttaa acttcttttc agtcttggaa cattttaaat caagtagtga
    10621 atataaaaat ttaagagcta cacccgattt gtcacctgtg ttttgagatt cgggattaac
    10681 tccttgacca aaaataatta tattcttttc taatctatca agaagctcct ttttggcttc
    10741 aactggtata tttatctcta gtttatcaac tccacctcca ccatctactt taattgattt
    10801 atagtatctt atattatcta taaactcttg tagacttgtt cctggatact cttttaatac
    10861 ataaatgacc tcttgcattt catctaaatt gtctgcaagt gtagaaatgt tattatcata
    10921 tatatcaatt aaagacttat agaaagttaa atctgagaca cacttttcat tatttttaaa
    10981 aggtataaat ggaactttac cccatccctg ttctttgtta tttattctaa aatgaccttc
    11041 ttgtatatca gtcatttttc catattcatc atataaaaat tcttgaataa aactattacc
    11101 tctttcaata aagtaagtta cgtcattttc tgtgtagtac tcaactcttt ttattttatt
    11161 tccatctata tcttcaatat aataaaacct aataaatgca actaattccc tctgtctttt
    11221 actatcccaa ataggaattg cttcttcagc tggaattatt acatatttaa actcaccttt
    11281 tctattaata tatggatgta accattcaac ccctttatta ctagcattga gatatagttc
    11341 tgttattgta tcgtcaaact cttctcctag taagtcattt aaaagcttag tgagattatc
    11401 atcatctgca ttaaatacta tgggatttcc gacactatag cctacctttt ggtcaactaa
    11461 aagcttatgg tagttgttaa ttgctttatt attaacttta gtaaaatcat caaccttagc
    11521 tccatctaag agataatatc ttctcttatt gtttacatca gtattaccat aatagtattc
    11581 ttctccttgt ttatattttt ctggcctatg ctttaagatg tagtgttcta tgacttttac
    11641 taggttaaag gtgctctctt tttttaactg aacttttatt aaatctgttt cacttatata
    11701 aatatttaac acctccttta ctttaagaag cttattccat tatttttaag cttattatct
    11761 atagaatatc taagagcagc cattgcatca tccataaact caactggttc atcaagatat
    11821 aatccagttc tttcgtcttg tttccatttc cattgttgta tttcttttat ggtattagtg
    11881 caactaggat gtacatgtat tcttaattgt ttcaaataat ctatttgagc tttaacactt
    11941 cctggtcctt ttttaactcc tttagcttta tatcctgcac tcttccacat cttaattcta
    12001 tctggttcag cactatcaca gtacataaat agagtctttt ctaaacctct actatttgca
    12061 atttttatga tttctgaggt atccatttca tgtacatata tttcattaca tatatataac
    12121 tctccatcct taaagccaat tctaagtatt gcatttgcat gattaaagcc aaagtcttgt
    12181 gacagtctca tattgtcaaa gtattcaaat tctgtgggaa attcatgtat aacataattt
    12241 ttaagtattg ctccaccagt ttctccccat tctccaagac catatacttt gtacccttct
    12301 gggtcttgct cttttctcat ttgcattctt ctgtagtaag cttcatctat gaatctattt
    12361 tgtagataag tactatgatg agtaaatata tcatcatttt tatagtcaaa atactttctt
    12421 tttatccaat gagtagctga gactggatta aatgtaaatg tcatttgata atacaagtta
    12481 ggattagtta aaatacctct taaacggtca tctagtatat ctatgtcact ttccataagt
    12541 tctgtagctt cttcacacca aacccatgtt aattttcctt tcgagaagtt aattgatttt
    12601 aatttttctc tttgttttgc atcattaact cctctgaaaa ttatagagtt accagtaact
    12661 ttactcttaa tttctaaagg atttaaagta gttttccaat acttatcagc ttgtttacca
    12721 taaatacgat ttatagctcc tgtaagctct gcatacgttg aatacttatg tgtagcttct
    12781 gactttctaa ctactaatag attagctcct tgatacttct tatctcctaa ctttagtata
    12841 tagtcttgtg ctacattaac agattttcca ctccctgctg aacctttcat tgctctgtat
    12901 ctttttttag taaaattagc ttccttgaaa tctggattaa aatttattct aactatcatt
    12961 tctatcacca taatctacac ttattttcaa ctcatcatct ccaatatcat ctttatttag
    13021 gttagcaacc tcacatttca acttctcaac tcttgttttc tgctcctctg tagccaaatt
    13081 ccaatcctta tgaatcattt catcatactg cttaattaaa ctccttaact cactcatagc
    13141 tctactctgt gcattaagaa aagatgcttg cctatcccat gcaaattgaa attcatactc
    13201 tatcttctca ctattttctg tgatttcatg tttctttaat tccttaatca tttcctcttt
    13261 atctttaaca tacattatct tctgtgctct tattattgct gcgtattgaa ttgttatctg
    13321 ttcccaaaga atatcaaatt tatcttttat agatatttct tgtattaatt ccctagtttc
    13381 ttcaggtaag tattttgaga agaaaccaaa cttttcagca tttttattct cttttggagc
    13441 accataacca actgaatttt tattagaaaa gggtgcaccc cttttattta taggtgcacc
    13501 cttctttttt tcactagacc aattgtatct ttttatccat gactttaaag tatttaaact
    13561 aatgtcatac tttgctgata tttccttttg tttcattcct tttaagtaat cttgttttac
    13621 cttttctttg acatcttgca catcaccacc tctttatttg tttgttttgg gaataaaaaa
    13681 acaatcctat ttaataggat tgtttcaaat ctagtctcct ctatccttcc aggataaatg
    13741 aaacatactt attattaatg tagttagaga taaaattata tgaactgtaa aaaatattaa
    13801 aacatagaaa attatattag aataatatcg agtaagcatt attgtattga taaaacatat
    13861 tacaacaacc aaaatctcca ttattacagt ataatatgct tttaactgta tgaattgaaa
    13921 gtatgatata ttaaatccat ttacctttct ttctgttttt atatcttttg cttctgatat
    13981 tgatttgtta tatgtagtaa acaataatgt aataatgcaa actccaaaag ctactaatag
    14041 tcctgacaaa gttagtacat ctttgtttaa agaaattaca acttctttat taattgacga
    14101 attaaaaaac atgtatgaaa taatacatat taatactggt gttaaaacta actctactac
    14161 ttctttagaa tttatagcct tgtaataatt gagtaagata tttaatacct ttttatacat
    14221 tttaacacct ccttagcaat ctatgcttca ctcatagcaa cttcttgata cattaaatta
    14281 aaaaaaactg aattattctc aattaaatca tctatcaaat tattcatctt ctcaaaaatg
    14341 tcttcactat ctatatgatt atctatatca agagaaacct ctatttctct acacaacttt
    14401 ataccctcag tatccaactt taattttctc ttatttttct ctccctcaat tattatccta
    14461 tttatttttt tatttctaaa ttcctctcct ttaatatatt tttcgcaaca tcttttaact
    14521 tcactaggta aatatctagt tctaaatgtg ggcttatata tcaaatcgtt atgtcgtctt
    14581 gaattattta aattagaaaa caaattatct tcatcagttc caaacttctc tctatcaaca
    14641 tttaaagtta tttttgaaac accatctaaa tctaatattt gttctataaa atctttactt
    14701 gctatttgtg taatattaat tgatgttttt gacatattat tatcaaattt attattttca
    14761 atcatatcct cataatatag atgtaagttt ttacttagtt caatcatggg aacccccaca
    14821 aaaactcttt caaataatac tactgctata ttattttcct tcataaattt aataaatagg
    14881 tgctgcttat tgctatctcc ttgatccatt tttttattac cctctacttc tttagtatga
    14941 gcatttataa tatttgtatt ctgattgtat ttagtatatt caagtttcac cttgattatt
    15001 aaatcatcct cgctacattt tacttctgta atccaaaact ttttatcttt agtaatatta
    15061 attccatttt tgttttcttt acaatattct ttatccttaa agaaggtctt tattacctct
    15121 tttaaaattt cttcatctga atagacactc ccattaattt tatttataat atctattcta
    15181 taaacatcaa tatatctttt tttaaaatta ctcattatac cattattcct ttcacaaata
    15241 tttataatga tataattcta tataatcagt caatatcctt caataatcat tcgacaacca
    15301 caaaataagt ctaaataata cttttacctt attcctgtct ataatgtaca aatatatttc
    15361 atttttaatt cattacataa aaaaaaagac cctctattaa tacagtcatt taaatcattt
    15421 cgattaattc tttaatcttt ttatatacct ctttataatt cataccttta tctatcaacc
    15481 taggtaattt catagatata actctttcaa gtacttgtat taataaaaaa actcttgtat
    15541 ttcatctgta aaatcttttc tgacctttta ccttctgttc ttatatccag ccattcttga
    15601 tctttttctg tggcaatata gtaaccatgt attctaattt gtttaagtgc ttttgtaacc
    15661 cacttcgtaa atagttttgc ttctgcttta ttacttctaa atgacatatt gtacacagct
    15721 tcttctgtaa caaaagtagt accaaagtta ggcaatttat ctttaaagtt tctagtgtag
    15781 gaatctccga cagtagactc attaaatttc tttttatatt ctctatctat atttcttaat
    15841 gtatcacgaa tatttactat gcctagttcc tctcctacgt catttgcatt aaaccaaact
    15901 tcttctccat tttttgacca tatcatcctt acatttttct cttgtaaaat tttcaacata
    15961 ctactacctc ctaaattagt tattaataaa gaatattcaa tttgaacacc cttattttcg
    16021 acccttcaat atgagagatt aaaattgtat aaaaaaagac ctagaaatca ctctaagtca
    16081 tgaattactc atttatcatt ctccttattt acaaaataaa aaagactaag ttggggtaac
    16141 ttagcctttt tcaaggggga atatattata cacttgtttc atactaccat tataacaggg
    16201 gttaaatatc attaaaatat catcttttta tcatgtattt atcaaacagt taatttcaag
    16261 ccatctatac caaataaata cactccaagt tcttttacca tttcattaat ccaacgtctt
    16321 gatgtaacta ctccacaatt taatatctct gctatttctt catatgtttt ttcatcacaa
    16381 tagtaaagct ctaaagctct atacttttca taagaatgta aacgctcttg tcttaatttc
    16441 aaagttttca ttgctgaatc tatatgtgct atcataataa tagttcttgc tttacttttc
    16501 tttatactta aaatatacaa ctcttcatta tcaagcttac ctaaatcatc ctctaagtaa
    16561 tctacatctt tagcttcact taccgctgag tctatatgtc tcttaaaatc attataatgc
    16621 ttcatcaata atctagtatt atataaaacg ccttttttcc tatcttctct ttcttctttt
    16681 cttaactctc ttacaatttc ttttatactt tctttatcca cttaaatcac tccttcttgc
    16741 tctcttcgaa caacttctac tgcaatactc aactttagat ttatccaact tataaaatct
    16801 tctaccacac caagcacatc ttactatttt acctgggctt ataagttcca tcttttcttt
    16861 ttactttcat accttcactc cctatattct tttaattttg cttttactgc ttcaagtaat
    16921 gcactttgcc ctttatcctt attctctata gcttccatta cttgttcatc tattgtacct
    16981 ttacagatta gatgatggat aataacagtt tccctttgac cctgtctata aagccttgca
    17041 ttagcttgtt gatacagttc taagctccaa gttaatccaa accaaacaat tatacttcca
    17101 cctgattgta aattaagtcc atgtcctgta cttgctggat gacaaagtaa taattgtatt
    17161 cttccattat tccaatcata tatatctttt gagttttcta ttgttcttgg tttcaaactc
    17221 ttaaactctt tcattaaacg attataatca tgtttatagt tataaaaaac tataataggc
    17281 ttaccatttg aaacatctat aatttctttt aaagcttcta atttttctct atggagttcc
    17341 tttacatttt tatcattatc ataaattgct ccattagcta attgtaaaag tttatttgct
    17401 gctacagctg ctgatgaagc tgttattata tctctatcta attctaatat cttctctttt
    17461 tctaattctt tgtaatattt aagtatttta ctatcaaggt gtatttcaat tttattatct
    17521 atttttctag gcatattcaa ataatcttct gcttttaagc ttatacaaat atcttttatt
    17581 ttattatgta ttgcattttc tgctccattt ttaggttgcc aattatatat agctcctgtt
    17641 tgataatttt tttgtcctgg ctcaaagtat cgttctttat atcctgtaat agttttacct
    17701 agtctttcac ctctatcaag taagtacatc tgtgcccata agtctattaa actatttggt
    17761 gttggtgtac cagtaagccc aactactctt ttagttaaag gcaatacttt ctttaaactt
    17821 ttaaatcgtt gtgctttatt tgatttaaaa gaactaagtt catctatcac aaccatatca
    17881 aatggccatt ttcttttata aaaatccact atccagggta ccatttctct atttattata
    17941 taaatatctg agtctgtact taaagctctc actctatcta atttactacc aagaacttta
    18001 gatactttta gatgctttag atgttcccat ttttttactt cactactcca ggtatctctt
    18061 gcaactctta aaggtgctat aactaaaact tttgatatat caaagtaatc atacattaat
    18121 tcacttatag ctgttagagt acagactgtt ttacctaatc ccatatctaa tagtaaacct
    18181 atattattat tatctatagt ttttctaatt gtgtattctt ggtatggatg tggtttaaat
    18241 tccatccctt aacctccttg ataaaatcat ctatctcttt taatgtgctt acacacttaa
    18301 ctttaaatcc taattctctt aattctcgca ttttatattg ttgaagcttc cttagttttt
    18361 tacctggtgc tttaagttct acaaatataa catgtccttc tggtaataag acaatcctat
    18421 ctggcacacc tgcctcacct ggtgaaataa acttcatagc ctttccacct aacaactcaa
    18481 tctctttttt aagtcttttt tctatttttg attctaacaa aatatcactt ccttaaaatt
    18541 taagtgtcaa caatgtcaac agattttcta tatatatgta tatatacata ttaggcatac
    18601 atatgtatat acgtatatgc ctaatattac ttatactact ttatacttaa tttttgttga
    18661 cattgttgac attaatacct caaacattgt aattactgca tcttaggtgt caacataagc
    18721 gtcaacaaag ccattttttt tgttgacatt gttgacactt ttaaaatttt caaatttact
    18781 ctgtttttaa ttctgttgac actaactttt acgtacataa gctctctgcc taccatatat
    18841 tttcccaaac cttaaatttc cattatatga tatccaatca tctaatcctt ttaatatatc
    18901 attaatttct cttgataaga taggcgtgag ttgtttaggt tctccattaa atagctcaac
    18961 ccatatctcc ataacacacg ttttttctct taatattgtt ccttctttta aatcaccaaa
    19021 atctgaacca tgaatatatt ctctcttttc tgaaatactt aaatcatacc aattctcagt
    19081 aataggttta tttagatact cttcgataat tccagattta gcattttctt ctgagtgagt
    19141 tctttgttgt ctttcagctt cttttttctc ctcatctgat agatatagct gttcattggc
    19201 tttacataat tctactgctt ctgcccaaat ttgatttctt tcattatcaa gttgaccatt
    19261 aaatatactc ttgttaacct tctttactcc tgtatctatt ggccaaaacc ttctattccc
    19321 ggtcttatct cttaaaaatt ctttatcatt agttgttcct ataactacac attgacgtaa
    19381 aaaccttgat gttctcttcc catatgcgac cctatatata tcctctgatt tgcttagaaa
    19441 atgcttaact gcctcaatat ctgctttttt agtagccatc atttcaccca tttccagcaa
    19501 ccatactcct tgtaattgtt catacgcttc tttaccttgt acagtagtta aactatcaga
    19561 ataccagtct ccaccaagtt ttttaataaa agtacttttt cccattcctt gaggaccaga
    19621 taaaaccatc atattatcaa actttattcc tggattaaat actcttgcta ctgctgctac
    19681 taaaactttt cttattatag tccttgtata gtggttatct tctgcaccta aatagtcaat
    19741 taaaagtgta tccactctct taatgccatc ccactttaaa gaatttaaat aatcttttat
    19801 aggatgaaaa gtattatttt caaaagcaat tattagagca tcatttactt ttgatggtga
    19861 tgagatattg taaattgttt ctatatgatg tctaagccca gaatcatcac tatcattcca
    19921 atcatttaat ttatcatctt ttctccaagg taacttacct aaaacgacag ctctatttga
    19981 aaattcatta taagctattt ttcctttcaa atatgggtca ttttctataa acattaagat
    20041 attgtttgtt gttttcttat aacttccctt attgtcataa tctaacctag ttaaccattc
    20101 atcatcttca aaatctatat caccaaaatc atccttagct ttatcaaggt tttctcttcc
    20161 tatagtcttt cgtactttag tgtcactgct tgcaaattcg ctcattcgag taaatgaagg
    20221 taatctattt acaggcgttt cgggtttagc atcttcatca agttcaccaa atttatgtat
    20281 cctaactaaa tcaaaagcat tgcataaaat tccgcttgct gggtctgtac catgatgact
    20341 atatgaaaac ttgtcatcat aaataactac tccaccactt gtactacctt ctgaatatgt
    20401 atacctggtt tcatcaatac caggaatata tacttcattt aagaaatttt ctatagtttc
    20461 ttttatacta taggacctgc aaaatgcacc tataattcca gccttttcaa tagggtcttg
    20521 ttgttttttt aattgtgtat taaacttttg cctctccctc gaactttctg gccaatagct
    20581 tacatctgtc cagtctaaat ataaatctag tatttcattt gggtttaaaa actctccatc
    20641 ttgaaattta aatatatagt ctccatcaat tgaagtactt ggaaaataca taagtctatg
    20701 aggttgatat gtagtatcat caaacatatc tattcctata gtatctgcta tcatcctgga
    20761 aattgcttga tattcttctg gtagtactgg tctagttaaa ggtattacaa gtctatatct
    20821 gggattattc tcagtatgtg agtgcgtaga atacataaga caagcataat catttaataa
    20881 tgttatatcc tcccatatat ctttattcgc ataatctata tctaaagtta taatacttct
    20941 atttgcaata ttctctgctt ttcgtcttcc attttttaag cttccaccta caaatccacc
    21001 aacatcttta actctatctt tttcagtctt tgacatcttc ctatattctg tatatgtttc
    21061 ttgagttctt aatgttttac ttaatctatt tacaagttcg gaccataaaa tacttttatt
    21121 tttccaatgt gtttctaatt tattttttcc tatggccagc atgagttggc catcatgtct
    21181 tacatttatg tgttcaattt cactggcctt tatatccata aatcaatcac ctagtctttc
    21241 ttataataat cacattcata tccatctgct ttaagaggaa gacctttagc ccaagatatt
    21301 tcttttccca taatactgtt aacttcttct aaagaacctc cttttttatc tacatcaatt
    21361 acaagctcat catgtacatg cattacaatg ctataacctg catctgtcac attaaacata
    21421 gcctctctta agcaatctct agctgtagct tgaacaatat tctcaactaa cttaggtcca
    21481 taagtatcta ttcttttcca ttgtttactt gtctgttcca taccttcata tgttatctta
    21541 tccccactaa atgtagtatg aggctctatc ttaggtctta gatatgataa tcttctacca
    21601 cttggtagtt ctataaataa aactcctgga ttataaataa atttaatccc atgttggagt
    21661 tttactatag tcctatcttt tatggctttt ttagctgcct tatctacatc ccaccaaaat
    21721 ttagttatat ttggattagc atttctccat gttgttacaa gaggttgaag ctcctcttca
    21781 tcaagaccca tttttatagc ccccattgat gttaaagctc ctatgcttcc cccatatcca
    21841 agagctagct ctgaaatctt acctttttgt ctaagtgggt cacctttttt aatactttct
    21901 attggaactt taaacatatg actagcacta gcttcatata ttttcccgtg agaattaaat
    21961 acatctaatc tccacttctc accagcgaac caagctataa ccctagcttc tattgcacta
    22021 aaatctgata ctataaatct atgaccttca cttggtataa aagctgtcct tatcaattga
    22081 cttaagacat ctggtacact atcatataaa agctctatta aatcaaaatc tccttctttt
    22141 aataggtttc tagctaggtc taaatcctct atatgatttt gtggtaaatt ctgtacttgt
    22201 actaatcttc ctgcccatct accagtccta ttagccccat aaaactgtag tagacctctt
    22261 actctattgt cattaccttt agctaatttc atagcctcat atttctttat agaagttttg
    22321 gacattaatt ttctaagttc taaaattcta actacatttt catcatcaac ttgttttaat
    22381 atttctggaa tactttcttt tgttaggctt gtaatctcaa agccaacttt atcacttaac
    22441 cattttttta attgagctgg actatttgga ttatttagac cagttatttt aattgcttct
    22501 tttgtaagtt tttcagtata tcttttatca cattctattg cattctctat taactctgta
    22561 tcaactttaa taccagtatc attaattctc tggtctaaat accataattt aatttctctt
    22621 tcggtagtct tatacttact aagtttgttt cttatttctc tttcaactac aacatcttgt
    22681 ttacaatatt ctttaaattt attccatttt tccatatcat gtattggtaa atttctagtt
    22741 cttcccttgt taacttttgt agccttacaa ggtttacaga aatattgtat taatgcttta
    22801 ccttctttca ttttctgttt atcttcatta aactttaaag ccttagacac actatctaaa
    22861 cttcctggaa gtcctagtgt taacgccttt atcattgtac atgaccactc atttggtttt
    22921 aaattaatat ttaaaaattt acttattgct gttctttcaa aattagcatt aaatgctgat
    22981 tttataactt tattatcatt taaagcttct attacttctt ttggtaactc ttcatcattt
    23041 actaaatcaa taacttttac ctcttcatta tcaaaagcat aggcaaataa cagtatctca
    23101 aaattagcag agtctacata tctgtagact ccaacttttt ttatatctaa atcactatat
    23161 gtttctatat caattgataa ggtcctcatt aacttaagaa gtcctcttct tcatcttcat
    23221 attcaaagtc atctgagaaa tctgcttctg cactagctct agctcctcca agtacttctc
    23281 catctgctaa cttttgaaca ttttgtaagc cacaacctat tcctttattt cctgcactat
    23341 tatatgggaa aaagtttata ctaactcttc cataacaacc actatatacc tctgtattat
    23401 ctaatatttc atttaagtct ttatcaacta ttcctggctt ttgtgtacta tttgcattta
    23461 aaaaatacat tcctacatat tcctctgctt catcagctct ttctgcatct ccatcacgaa
    23521 gaggtgtttt taaattacct ggtaattttc caccccattt agaagtttta ccttgttctt
    23581 tagctgcatc aatagccttc tttattcttc ctaaagtcac cttatctgat tttggtatta
    23641 aaatacaaac tgaatacttg ggctctgcac cttctaccat tgctctgctt ttaaagatat
    23701 tgcaataact taatcttacc tttcctgtta ctacctttgt tgattgtact gaattactca
    23761 taattttctt cctcctaata tttttatatt tggtatattg attttatatt tgaagttatt
    23821 tctccaaatt tatctaaatc tctaacttgc ttactaaaca atttaattct tccacaaata
    23881 actgttgaag aaacatttaa taactctcct atatcagata tctttttatc ttgtaaaatc
    23941 caatctacta ttttatcaat atcttttaaa tatgactttc ttgcaatttt tcttatataa
    24001 tcaacatcat agttaaattg aatttcataa aatccatgta tatcttttaa tggtctttta
    24061 ctatcttcaa atacacttac atctaaacct tctatagagt ttctataatg tttttcgcca
    24121 taacgcaaag ctttaaacat ttctattctt atgtaagaaa cagccactgt agaaaacttg
    24181 cctctgttac tatcataatt taatgctgct ttatataacc caatacatcc ttcttgataa
    24241 aactcttcat ataagtatgg atgttgctct acataagact taaaaaatct atttatacta
    24301 aaatgtacaa gattcaaatt attttcaact agtttagtta tttcttgatt actcataaaa
    24361 ttatatcccc ttttaaatct ttttatagct actaggaatt aaatattttt aattatcctt
    24421 tgctcttact gatacaaagc atactggact aacttttata tgttctggta tatacactct
    24481 atcaagatga ttgtcattta cttcgaggaa agttgacatc actttatcct ttattaaact
    24541 ttctctttta aaatccatca ctataacttt tgcattttct tcagttgagt tatattctgt
    24601 aatatttagt ctctttaaca tatctagtaa attatctttt tcataatcta aatctttttc
    24661 gatactcttt tttctatcct ttaaatctaa aattatactt atgctttcat ctaatttatc
    24721 ttttatacct gcatctaatg gcatgtaata tcccccattt atatttcaaa atcttttttc
    24781 gctgaatcta tactattaat ttctgacctt ttatcacttt ctactactaa agtagctttt
    24841 ccaactggtt ttataattaa atcacttagt agtttagcaa aactcttttt acctatagct
    24901 ttctccatat cactaattcc ttttaaggtc cttggcttat aaattttttc ttcatcataa
    24961 tctgaattta ataaaacctt agcaacttct tgctcatcta catactttct attacttctg
    25021 ccttctacaa gcttatatcc tggatattta acaccatgct tttcagcttg ttctagtgca
    25081 taactttgaa catcctttaa ccaatcttgt atattcttag caaaacctaa aatatctgct
    25141 atctcatatt tattaagagc aaatgtgtca gcaaaatcat attttctagc tagtttaagg
    25201 ttatcctcag ctctttttct gcaatcattt ttagctctac aaaatccaca atgactgcca
    25261 cttacaaact ctccttcacc attaaaagcc atttgagcct tcttcttaac attatctgcc
    25321 catgtaagta atttagtaac ttctatttct tcacttgata tgttatcaag tctaggttga
    25381 attattgttg ttttaattaa atcaatatcg tatagcattt caaactgatt atatgcccct
    25441 aaaccatata gtctaagttg aggattctct atagctgaaa cttctaaacc ttttccatac
    25501 tttaggtcta taacttgaag tataccatca gatattacaa caacgtctcc tgttccaaat
    25561 ccttctggaa cccactcact aaaatcgagt ctttcttcta acatcactat tacatcatca
    25621 catatagctt tactatcatt tactaattca actacattct caacataaga ttgtatatag
    25681 tcctccattt cagagttata atactcactt ttctgtatct ttttaattct tgcattatat
    25741 gcctttttac ttattttttc atactctagc attaatttaa cttctgctaa ttcatgtgca
    25801 actgttcctt cttctgcata tatactagtt aatggtggat agttttcttc taattttata
    25861 ctaggagtgc agtgaagcca tctatgggct ccactcgcac taagtcttgc atgttgtaat
    25921 ggcatttatg taccccctat aaactttcta atttgttcat aaaagctgaa taatcttctt
    25981 cttttacttc acttaactta ctagctccaa attcaccaaa taactcctta agcttatcct
    26041 tcttacctgc cttacttact tgtgctgcct tagttcttac ctcttctttt gtgtatttaa
    26101 cttcactagt tgtattttca ttattctttt ctatttcttc ctttgcttct gctatttctt
    26161 ctttaacgtc ttcttttact tctacctttt taatcttttc agctttttta acttcaactt
    26221 tcttctcttc tttcatatct gttatattta taggttctat ctgcattgct tttcctagat
    26281 taagacctcc taaagcattc gccactacta atagtgcatt tgtaaattct ggtgcttcta
    26341 ctttaacttt tacatttaca ttaacttcaa ccattttaaa tatctccttt ttgtgttata
    26401 ctttacttgt gttatatttt attttttatt tttttgtgtg ttggttattt taccaacact
    26461 tttttattta atattccaac cgatattttc ttaccagttt taatatcttt aaatactata
    26521 tctgctataa cttttccatc ttttttaaga gttactacat tcttattatt agtatcaaga
    26581 ctcagcaatt tcatcccccc actctactgc ttttaaaagt tcatccaaat ttttaccttg
    26641 atttctttca ataaaatcat caacttcata tcttgaaatt tttctaccat cacctctaac
    26701 tagtgatttt atcaaacctg tgcttactaa cctacgcata aaagctgtat ctaactttaa
    26761 aattcccctt gcttcttcta ctgttattag ataatttgga taacctcttt ttattaaaac
    26821 aactatatct ttaggctcca gtacctttac cttttgttca atagtttgac tcttaactct
    26881 atctgtctct tgtttactta tctctatttc tattaaactt tttaaactat cactaaattg
    26941 ttttgctata ctctcagaaa tatccatgtg aaaattctct cccctctttt taattattta
    27001 tcttccaact aattcgtcta atgtaatatc taaataatca gctaatttta ttagagtatc
    27061 tatagttgga ttagaacttt tatttctcag taatttatat aaaccactta catctatatt
    27121 caattctttt gccaatttat aaggttttat atctcttttt cttagcattt gctttatatt
    27181 gtcgcctatt aacattgtat tcacctcagt tctacatggt ataatataaa catggaataa
    27241 attccaaaat tttcaaaagg atggtgtatt atgcagtttt caaacaatat atctaaagaa
    27301 ttacaagaaa gtataagaaa gacagtctct gatacttcta acacagagta tttttactat
    27361 gctgaatttc aatataaaat tattcttaaa tctatagagg aatttgaaaa agaacttgat
    27421 gatgaacatg aaattgcact aaaattgact aactttggaa aagatgtctt aatgattgtt
    27481 gaagaagtag gttatcataa cccttgtcta attcactact acggcatagt aaatggagtt
    27541 tattctgaaa ttcttcaaca cacatcacag ataaacttta tgataacttc agtaaagaaa
    27601 actgaccctt caaaacctgc tagaagaata ggttttatat tgtaattatc attcttattt
    27661 tctgattctt tctttagtaa tttcactaat ttttcttttt tcacttttat tcatctcatg
    27721 taaatacaaa actatacatt ggtacatata atctataaaa tcactatttg attgagctgt
    27781 tatctgacta aataactgtg cttgcaattg attttcaagc atggttattc ttttctctat
    27841 ttcttctatt ttcttatttt ccaattcaat ctctcctttc taaaatattc tgtatttagt
    27901 tttcaaagta ctaacctaat attgaagttt gataactata tcctttttct atatctggta
    27961 atatgttatt tgttttcaat aaatcatata aaaacaatct tcccttttga gtccacttag
    28021 ttgtcatttt tacatcaggc attccattac ttctagttat gtctattgtt tctgaatgag
    28081 tgtatccctt cccttgatgt tgtttatata aaagccattg tccactttgt ttatattgaa
    28141 tccctctttc atgaagtatt ttattcattt cttttccact cattccatag tcttttgcta
    28201 tttgagttat tgtgacaagt cctttatttt ttaatatcat atctgtataa tctgcctttg
    28261 gttttagttc ttttattact tggtctttca ttttactttc tagttgtaac tgctcattta
    28321 cttctacttg ctctataaga tgttgtaacg cttctttata tgtagttggt agtttagttt
    28381 gcaaatctat catattatat gtcccagtac tacgtatact tggtaatatc tcattagtta
    28441 cccaacgttt aaataatttt gcacttggca acttagaact taatattaaa gaataaagac
    28501 cactttcatt aattactttc atattttgat taccaccagg agtcggtatt tcacctactc
    28561 ctttatcttc atcatcaaca tgtcttttca aagcatcaga tgtatcttta tatcctaatt
    28621 gttctgcaat atcttttcca acaaaccaaa attctccatt tagttcgatt actcttattt
    28681 ctccaaaagt cttatttttg aatatttgta aattattcat aatttctttc ctccttatga
    28741 ttgtttttgt gaacaataaa ttttaattta tgttaacctt ttttctaaaa aaagttcatc
    28801 cattgtttta tttaaaatat agctaatcat tatcatttct ttttccgtaa aatttctttt
    28861 tccattttct tttagattat atgttgattt tgctattcct atcttatatg ctagttcttc
    28921 ttgggtatat cctgcttcta ttcgaccagc ttttaaactt cttttcttca tgttcttcac
    28981 cttccaatgt tttatttttg tgaacttcat acttttatta tattcacaca aacaaaactt
    29041 gtcaatacat aagtttattt ttttgttaac ttttttattt ttttctaaac ataagtttac
    29101 gtttctgtaa acttatagta tcatttaatt attgggaggt gttgtttgtg gcaacttttg
    29161 gagaacgttt caaacaatta cgagaagaga aaaaacttac tcaagatgaa ctagtttcaa
    29221 aattcaataa agtttacttt acaagtttta ataaatcaac aatatcgcaa tatgaaaata
    29281 ataaaagaaa accagaaata aatattctag aaaattgggc agattttttt gatgtatcaa
    29341 ttgattatct tttgggtaga actcttgtta gaaatcacat cgatactgta gccgcacaca
    29401 gagttaatcc tcacaaagat ttaccagagg aagctcaaga acaactcaac gattatattg
    29461 aatttttaat gaataaatat aaaaaataag gattgaatct atgttaatat taaaaaaatt
    29521 gagaactgaa aaaggaattt ctttagataa attaagcaca gacttaaata taaataaatc
    29581 cactttatcc agaattgaaa atgggttaag agaaccaaaa gaatcattta ttaaagattg
    29641 ctcagactat tttggagtat ctacagatta cttaattgga aaaattaaca tagatgattc
    29701 aaataaatta acaaaatgct taaattcaac ttttccaata aggttaaaag aattaagaaa
    29761 gaaaaaagaa ttaactcaag cagaattatc aaaattactt aattgttcac taagcaaaat
    29821 tgctatgtta gaaactagca aaagagaacc tgttaaagaa gacttgttaa gaatttcaga
    29881 attttttaat gtgtcagttg attatctact tggtaaaacc tcaattgaaa attacataac
    29941 tactgatgaa atatccaaaa taattaaatc ttatgaaagt ttacctaaag aagcgcaaga
    30001 acatattaat agctacatag agtttttagt tgatagatat aaaaaatgaa tatttagagc
    30061 agttcactcc tgctctttat atataaaaaa gtaacacata cattcttttt atagggggat
    30121 ttcaatgaac aaactagacg cacttttaga cttagcaaat aatgaagaga tagaaattta
    30181 ctacactgac aaaatagcag atgacataaa aggattgtat ataaacagac aaggactaaa
    30241 aattatatca ttacttaatt cattaaaaca aaacaatgct aaactaatag aaatcttagc
    30301 agaagaatta ggacatcatt ttaccagtgt tggaaactat gtatcttcaa aaaacagtta
    30361 caaaaataaa atcttgatag acaaaactga aaacaaagca ctaaaatggg catgtgaatt
    30421 tcttataaca gaagaagaaa taatacatgt tattaattca cacgctacaa gtgtatacga
    30481 aatagctgaa gaattacaag ttagcatcaa cttcttacta aaaagattag aatttctatc
    30541 aaaaaagaaa agcatgttgg acttaggaaa taatagattt ttagtattaa ctaatttgcc
    30601 aaatttctac atatatgagg atatttttta aactcattta ttctactttt atagattttt
    30661 tactt
//
LOCUS       DAMJYN010000042        30479 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.043, whole genome shotgun sequence.
ACCESSION   DAMJYN010000042 DAMJYN010000000
VERSION     DAMJYN010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 30479)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30479)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30479
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.043"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            230..1309
                     /locus_tag="PC466_002105"
     CDS             230..1309
                     /locus_tag="PC466_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HDF2769488.1"
                     /translation="MPELLKNMYNRESLYEVAVAIQSVYNSFKVDEFIKSTMDETWNN
                     LELKARCRKISMSLGMYLPEDYKEALSILEKSVTGFYFAFFFPDFVEVYGQDEINWDL
                     SISALERNTEYWSSEFAVRAFIIKDEERMMAQMRKWSKHKSEHVRRLASEGCRPQLPW
                     GQAISKFKKDPTPVLPILEQLKTDTSTYVQKSVANNLNDISKTHPDLVISIAKDWYGK
                     NKSTNWIVKHGCRTLLKKGNRDVLALFGYDDTTSINLQDFTLETTSISIGEDLTFSFN
                     ILAKKATKTRLEYGIDYMKSNGKRNRKIFKISEVSLKENEKKSYMKKHSFADVSVRRH
                     YPGIHSITIIINGVEKGKLDFELGV"
     gene            1633..2001
                     /locus_tag="PC466_002106"
     CDS             1633..2001
                     /locus_tag="PC466_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HDF2769489.1"
                     /translation="MDVYSFWNDTLAQDAVKIRKYFHEDAYINWHDTNEHFTLEEFII
                     ANCEYPDKWNGKVERVLEFGNLVITVTHVYAINKPLSFHVVSFISLKDDKIISIDEYW
                     GEDDDVPQWRLDKHIGKPIK"
     gene            2118..2921
                     /locus_tag="PC466_002107"
     CDS             2118..2921
                     /locus_tag="PC466_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF2769490.1"
                     /translation="MEEKYILSDRGKVYYWIKESNSVFAKNLIFLPGLTANHHLFDFQ
                     IQYFSKNHNVLVWDAPAHGKSRPYLDFSYSNLVEELKVILDKQNMKKVVLIGQSAGGF
                     VAQSFIVKYPNMVEGLMMIGTCPYGTDYYSKSDIFWLKQTEWMLKLFPDKLLRNIISK
                     MCGATSEGRRSMMKMLEGYEKKELCHLMYLGFAGFMPEIQDLNIHCPVCLVVGDKDKT
                     GKVRKYNEQWHNKTGYPLHIIKNASHNVNVDKPSELNQIMDIFIKQLNI"
     gene            3306..4196
                     /locus_tag="PC466_002108"
     CDS             3306..4196
                     /locus_tag="PC466_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HDF2769491.1"
                     /translation="MIESIPAKQILQKVKFDNTRWFGIDYNMNLYRGCSHGCIYCDSR
                     STIYNIENFDKVRYKENVIEILSKELRSKRKKGVVGIGAMSDTYNPFEKQLCITKQAL
                     DLISENHFGVSIDTKSSLVVRDIPILQKIKKNNSAIVKLTITTANDELSKKIEPYVNP
                     SSARFDAVKELNDSGIFCGILLTPMLPFLTDNKDEIRAIVEKAHKANAKFIYCMYGVT
                     MRSGQREFFYEHLRDISPKLVLKYQKTYGLNYVCTIQNKDSCEKLLREECARYGILTD
                     MKEIIKAYKRSESYIQIKFF"
     gene            4659..5102
                     /locus_tag="PC466_002109"
     CDS             4659..5102
                     /locus_tag="PC466_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2769492.1"
                     /translation="MIEIKTIEINKKSQIDLLMLADPCEEMIDKYLNKGTMYALYDNK
                     ELTCIAVVNEISKEICELKNIATYEHFQNMGYASKMIYHLLDVYSKKYSSMVVGTSES
                     GVPFYEKFGFVYSHKIKNFFVDNYPEPIFEGELQCVDMLYLSYNF"
     gene            5274..5444
                     /locus_tag="PC466_002110"
     CDS             5274..5444
                     /locus_tag="PC466_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769493.1"
                     /translation="MDSNNNTIKSTVKKGISFGSCLAMIISYTAWKSIPWAIFHGLMS
                     WIYVLYYWVKYA"
     gene            5995..6903
                     /locus_tag="PC466_002111"
     CDS             5995..6903
                     /locus_tag="PC466_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HDF2769494.1"
                     /translation="MTSENVGEVVTEDGYAKPEYDEVFKSLFTLNNDYDLLANFINDI
                     LKDAPYANRNIKPFTHIKRIIKAETDPTINYIGEKRPRLYILAEDEESNHINIEMQRA
                     LEDDYLERAEYYLSRVHGRKLEEGKEYKEIGKTVGIHILNHVKYNHIEDYVNCLRLTM
                     DGHPNIYSSKTALYFIELPKIRKSSCIANRVLIWGKLIDNPSHIDIRILSKTDYVIKR
                     ALDRLKELGSNEDYLLNLKRGAYIMNKSRNFKEEIFQEGVEKGKREEKFNIIIKLKNK
                     GYNLSEICDIIDDLNKSEVEKIYNQN"
     gene            7083..7571
                     /locus_tag="PC466_002112"
     CDS             7083..7571
                     /locus_tag="PC466_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3841 domain-containing protein"
                     /protein_id="HDF2769495.1"
                     /translation="MKFYTIQTLEFWNNNKNNKYLSNDYSFILEDFDIPYKWMYSQMT
                     NRIYEFDDSMIWVWTKRPDLRCSGYLEKGKKGVLLEIEISEDNVLLSEFDLWHLPLMD
                     ITVELYEDEQIEKKVSWERIFDLELCSKLNEVNIEDLTLQGVTSKVPLSNVKLIKEFV
                     AK"
     gene            7657..8064
                     /locus_tag="PC466_002113"
     CDS             7657..8064
                     /locus_tag="PC466_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769496.1"
                     /translation="MSKQQTGIKSTLISEILGISYCIGATLVNKYFFKGSSIEYLPII
                     IWVLAMGAQWVYNKKYDDLIDEASKCILSRVNDIAIKVLFFSVAIVSIFLVTLDINVS
                     NLNIGMSLLVILFIQSLLKLILFIYFDRKGIYN"
     gene            8065..8283
                     /locus_tag="PC466_002114"
     CDS             8065..8283
                     /locus_tag="PC466_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2769497.1"
                     /translation="MSVLLKTKIKSYREKNLMTQGELAKSVGVRRETIVHLENGRYNP
                     SLKLAMDIAKVFDTTVEELFEFIEENNI"
     gene            9005..9310
                     /locus_tag="PC466_002115"
     CDS             9005..9310
                     /locus_tag="PC466_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769498.1"
                     /translation="MPSMIMEVVGVLFIAIGLILTFIEIKGNFPSFYGFGQNSIGKNA
                     VGIIAAGIALIFFRNGIDSIDSIATYGVFLAIELVVIVAYFLIRKKFTKEDKHLRTN"
     gene            9718..10407
                     /locus_tag="PC466_002116"
     CDS             9718..10407
                     /locus_tag="PC466_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2769499.1"
                     /translation="MDILLVEDDKNIREMVYDFLISENYFVKTAVDGNTAIEIFKNYS
                     FDIILLDLMLPKSSGFEVLKYIRSVSVVPVIITTAKDSDTDKMLGLNLGADDYITKPF
                     SIVELLARIKANIRRATVYSSSRNSEDMVIQYKDLIINISKYVVSKNGIDLNLTHTEF
                     EIVKLLATNQGRAFSKEQLYNTIWKEPYYGNENVLNTHINRLRNKLSDGIEKNNYIKT
                     LWGIGYKMEEE"
     gene            10407..11324
                     /locus_tag="PC466_002117"
     CDS             10407..11324
                     /locus_tag="PC466_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDF2769500.1"
                     /translation="MELFLVVISIVLFAFYLKERNKSKKMESDYKYINSRLRDITNDD
                     EINYILVPSDISIVKETAVDINKLLEKFYSRQINYNRSEKAILQIFTNISHDLRTPIT
                     VLKGYIEMLYLQSQKEELSSSMRATLEKMQTNSNELVNSINNLFNMAKIQSGDMILNL
                     QKSNLTQLCHEIILEFYDLLDKENFNVEVNIEDRPIYANVDTEALQRILKNLIDNAIK
                     YGSDGRFLGISLYEKEKHVFIDIEDKGSGISETEKEHIFTRAYTADRKKGNGLGLAIS
                     QGLANSMGGSIYVNSRPNVKTVFTVKLKS"
     gene            11397..12323
                     /locus_tag="PC466_002118"
     CDS             11397..12323
                     /locus_tag="PC466_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2769501.1"
                     /translation="MNYIIETHQLKKIYKDKAVVNDVNIHVKKGEIYGFVGPNGAGKS
                     TVMKMLLNLVKPNSGEIVMFSKKVAETDFEILKKIGTIIENPYFYENLTAKQNLDLHC
                     EYMGYYNKEHISEVLECVGLSKQSNKKVSKYSLGMKQRLAIARAILTKPELLILDEPI
                     NALDPEGIREMRELFRKLNTDYGITIFISSHILSEVEQIADTIGIIQDGKLIKEISMS
                     DIHKYQTDYVEVDVDNVELAGYLLEKEFGIKDFKITSESCIEIYDLRKDVKEISKIFI
                     KNQIGINSIGRKQSSLEDYFFQTTGTGGIETL"
     gene            12320..13000
                     /locus_tag="PC466_002119"
     CDS             12320..13000
                     /locus_tag="PC466_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2769502.1"
                     /translation="MIHLMKLELKKVGLKRYFLFSILGILLCMFFVFTGLNDKSTSIY
                     DYDVTFRTISLVFCFYYIILFAVLNVAYIINEYTNKTILILFSYPLDRKKLILSKLLL
                     ITTLMISSMIVGYICCFTFVVVLDKYFNLVIGDFHISILSYWIPGAIKSIIVFCSLGI
                     WTFVVGMIRKSIPVTLVSSIIFINLRQFILAGTNTTQDSLISVFIIVGITVIGIYYIL
                     NHKVTEID"
     gene            13445..14146
                     /locus_tag="PC466_002120"
     CDS             13445..14146
                     /locus_tag="PC466_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HDF2769503.1"
                     /translation="MNNSFLDKLIETKELKNSLYNVLKHNFLYHSNKIEGSTFTTEAL
                     ALLLDKNVVTGRHTLDDVQETVNSSYVFDTVIDSLKEKITHNFLRNLHSSLIFNTTLH
                     SRGMAGIYKTIPNMILGTDVSIAQPFEVEPKLDELIEWYYSQSEVSIKVIAEFHYRFE
                     LIHPFQDGNGRIGRFVMLKQMLENNLPIKIVSWDSEDLYRNSLNSCSLGNYVPLIEYL
                     SSLEDFREVYKMLWK"
     gene            15050..15700
                     /locus_tag="PC466_002121"
     CDS             15050..15700
                     /locus_tag="PC466_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2769504.1"
                     /translation="MKVKSNLDEILYHKIIESLIRGEYSVGQKILLNDLCEKFEVSRT
                     PVVQAVKMLNKDGVLTIMTNGKVYVPEYEYDMVKQVCETRTLIETYALEKMMQEEEEV
                     FQQKLDVIKRYSDKCEEYYRQEKSVELALADLELHKAIVEGANNEILNDVYVGIQGRF
                     IVVNYLIRPLKNRNYEGTVQDHFEILKFIEDRDTKKAVDKLRNHIQGTIKRFCEDE"
     gene            15978..18044
                     /locus_tag="PC466_002122"
     CDS             15978..18044
                     /locus_tag="PC466_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S9 family peptidase"
                     /protein_id="HDF2769505.1"
                     /translation="MKEVVESLKKITKERIENTMKKLFTSETFLEYQFISDCQISPDG
                     GYTAFIVKKADIKENGYTSQVYILNNKTGELKQITSINSVGAYVWEDENTILFPALRN
                     EKVKEAVKNGKQCMSYYALSLNGGEAEELFRLPIKGGKLNPIGKGLYAVIDSYDNDRP
                     IVEGLPEEEQQKKINAYNKRHYEHFKEIPYAVNGEGYISRKRKRLYIYDSNINKLKAI
                     TAPMFNVVGMKISDGKILYIGQEFKDVKGLKNGVYVFDTNTNTNICILEKDKYIIKGF
                     ELYQNQVILNLTDALSYGNGENGDFYTIDIDTKEMKLLSGHQHHCIGNTVTSDVKMGA
                     GQTTKVDGEYIYYTSTVDMDCIIERIHIPTGKQEKVTQTGSVDFIDVKDGNIVCVGCL
                     GNGLPEVYTVENGTLCKKTHLNDHILEEYKISVPEYIESKGSSKWEIQGYVYKPVDYE
                     VGKKYPAVLAIHGGPRLTYGPYFMHEIQVFTSAGYFVFFCNPRGSEGRGNAFADIRKQ
                     FGDIDYIDFMEFTDTVLEKYTDIDKTKLAVEGGSYGGFMTNWIIGHTNRFAVACAQRS
                     IANWSSMEGTTDIGYYFCKGQTGASHMENHELQWKQSPLAYADKCVTPTLFLHGEKDY
                     RCYMQEAFQMFSALKIHGCPTKLCLFEGENHELSRSGRPKQKLQRLVEMLDWFSVYIK
                     KDNIGQ"
     gene            18061..20016
                     /locus_tag="PC466_002123"
     CDS             18061..20016
                     /locus_tag="PC466_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S9 family peptidase"
                     /protein_id="HDF2769506.1"
                     /translation="MEKIKIESSDIFEYIFPHDISCSPDGKHIAYIISNINEEKDCYE
                     HDLYVMDIKTEKQIHMTQTKDVTSFSWISNTELLFTSKRNKPKAGTTDFYTISIEGGE
                     AKEAFSIPKACSVPVSLGNKLWLLTTKNPTDSKKSEPDRAVEGVDYWTFTDKPFIRDR
                     ENFSQRRRVTLELYQEGENITKAITPKFCEVAGIDVSSDKNRILYTGQIYEDCATPFS
                     GLWEYHIDSGETKELVPQGKYQISLAKYIGKDKVMLQASTLERSITQNHDIFILDLST
                     SEINMIASPDGMYATLLDVDAVYGGGRSNKVIGDKFIGARICRTMTEFNEFDTKTGNI
                     RIITKVDAFTSFDIYDNTMYTVMLKDYELAEIYSIDMTTGTMKKMTAFSKPYLDTHKV
                     SLPEKLTFVAKNKEEVDGFVIPPIDAKEGEKYPAVLFIHGGPKWAYGYMFTHLKQCVT
                     SKGMYVIYCNPHGGDGYGEKFLEMVERWGYVDYEHLMEFVDTCIEKYPGIDADRLGVA
                     GGSYGGYMTNWIIGHTDRFKAAVSQRGISNLITASLIIDFGDRIMKQTCGDKTPWNHE
                     EVLWNHSPIKYVKNVKTPTLFLHSDRDYRCFMGDTFQMFTALKQLGVDTEMYLFHGDT
                     HGLSRNGRPSNRIARANAIVDWFERYL"
     gene            20032..21222
                     /locus_tag="PC466_002124"
     CDS             20032..21222
                     /locus_tag="PC466_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HDF2769507.1"
                     /translation="MSDMLLWFSVVLVLFAIGDLIASKTKAKVSAVFVTLLLFLILFV
                     TKAIPADIIEKAGMTAAASWSVPMIMFSMGTMLNVKQFIDEWRTVLTAWLGIVAVIVC
                     VSLCIPLFGKSTVLTSIPVINGALPATTIMTQAALEKGLTLAAATATVVFAIQKFIGT
                     PIASRAALQEANRLLVEYHEAKSKGIDLANVDTDKKEAENTGTKVKQAFCEKYDKYYS
                     TNVCIFFIALFSYLGYELSEIIHVNYSIVCLVVGVIVTRIGIVPKDILEKGKIKGFIN
                     MVVFAAVIPSLAKVSLTDLISLFVPIVGMFAASIIGIFLMMKVLPGWKIIGSKPLAFG
                     VGFCQMLGFPTTYLISNEVCNAVGETEEERAYLMSKIMPKLVVGGMACMISIVVAGLM
                     VPML"
     gene            complement(22070..22253)
                     /locus_tag="PC466_002125"
                     /pseudo
     CDS             complement(22070..22253)
                     /locus_tag="PC466_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427897.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            22356..22730
                     /locus_tag="PC466_002126"
     CDS             22356..22730
                     /locus_tag="PC466_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2769508.1"
                     /translation="MKVLISNTSDKPLYQQIKEQIKEAIFTEELKEGDAMPSIRNFAN
                     DLKVSILTIRRVYEELENEGFLTRQVGIGTFVSTGNLEILRDSKRRIVEQKMADMIKD
                     AKALGITQIELQEMMGILYEED"
     gene            22732..23589
                     /locus_tag="PC466_002127"
     CDS             22732..23589
                     /locus_tag="PC466_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2769509.1"
                     /translation="MENILEVYNLNKTYTNFSLSNISFVLPEDCITGFIGVNGAGKTT
                     TIRSILDVVKRDSGKIKIFGKDFDGNEKELKNRIGVVFDDSYFYEELSMSEMKSIIAP
                     SYDNWCEEDYQQNMKRFNLNPKQKIDTLSKGMKMKFALALALSHKAEFLIMDEPTSGL
                     DPLIRSQILDILTEYMKKCGRGVFFSTHITSDLDKIADMIVMIDNGRIILEREKDTLL
                     DEHRKVKGDIQFLNDEIKKLFLNLEITGYGFIGITSKINEVQKNMPDILIERPTIEDI
                     MLAYIERRE"
     gene            23592..24230
                     /locus_tag="PC466_002128"
     CDS             23592..24230
                     /locus_tag="PC466_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 transporter permease"
                     /protein_id="HDF2769510.1"
                     /translation="MLIHLVKKDILIVKKYVLLILFIAIGIPLFILWRLPPFAQILGF
                     VLSIIFSEFMLCQYLLLKESQYSKASVLLCSTPYPRRGLVQSKYVLFAMVFIYCTLVY
                     WIENLLIPQIGTFDLTYILIVLLISSIIYGVYMPIQYKLGYETTKFFFVMIIMASSFV
                     LPLTIAHSNFEIPFIYQYPSMIVNIVLFLLSLIILLASMFISIKIFSNKELV"
     gene            25204..25938
                     /locus_tag="PC466_002129"
     CDS             25204..25938
                     /locus_tag="PC466_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF2769511.1"
                     /translation="MNLAKGLDVLKISSNVFGEDKVMYIPVIYTEDDATLIDTGLPGQ
                     GDLIIDALNKSNTSFDRLKNIIITHHDIDHIGNINYLREKSKNNIKVYAYKSEVSYIT
                     GEETPFKLYMLEQMVDKIDDKMLSMLNVMVLGFKSSYTKVDVSLDNHEKLNLGEEIEV
                     IHTGGHTRGHICLYLKESKVLIAGDLLQVENGELTPVDVMHSNKQELKDAIKNISNYD
                     IETIVFSHGGLYQRDIIGTLKNLIIE"
     gene            27080..28336
                     /locus_tag="PC466_002130"
     CDS             27080..28336
                     /locus_tag="PC466_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HDF2769512.1"
                     /translation="MIEKFKTLIWIKMIIRIKSVYKTYGGLFLLGLIGIPVGAIIGLI
                     DTIFGTVLLKVTDIRETYPMYLIPFLAVVGVVIAYCYFKFGGKSSKGMNLIFEVGHGE
                     EEIIPLRLVPFIISGTWLTHLFGGSAGREGVAVQIGATFSHWVGKRLPIKNASSIFLV
                     TGIAAGFAGLFETPIAAILFAMEVLVAGSLEYQSLFPAFTASFTASAVSKTLGLEKFS
                     FALSSKVVFDLPIFWKLIVLGIIFGMVGGAFAWCLKLSKRKIGNRLKNPMIRIAIIGV
                     CLSVLFLLFYKGRYSGLGTNLIQNSFYGGEIYSFDWLLKFILTILTLSAGFQGGEVTP
                     LFSIGASLGVLLAGFFNLPIELVAALGYASVFGSATNTFFAPVFIGAEVFGYSYLPYF
                     FVVCAISYIFNMDKSIYSLQKISTKQ"
     gene            28399..29592
                     /locus_tag="PC466_002131"
     CDS             28399..29592
                     /locus_tag="PC466_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HDF2769513.1"
                     /translation="MLTSLALIFLLGMASGGIFEKIKLPSLLGMLLTGIILGSYVLNL
                     IDNSILDISSDLRKIALIIILTRAGLSLDINDLKKVGRPAVLMCFIPATFEIIGMIVL
                     APKLLGVSILEAAVMGAVVGAVSPAIIVPKMLKLMEEGYGTEKSIPQMLLAGTSIDDI
                     FVIVMFTVFTGLAQGNSISAISFLQIPVSIILGVIVGAVIGICLAVFFKKVHMRDSAK
                     GVLLLSISFLMISLETALEGIVPFSGLLAVMNIGIFLQIKYRVVARRLSVKYSKLWVG
                     AEILLFVLVGATVDISYAFKAGIGAVILIFGVLLFRMVGVFFCLIKTNLTIKERLFCM
                     IGYIPKATVQAAIGGVPLAMGIASGQLILTLAVLAILITAPLGAFGIDVTYKKLLTSV
                     EGKSK"
     gene            29799..30179
                     /locus_tag="PC466_002132"
     CDS             29799..30179
                     /locus_tag="PC466_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF2769514.1"
                     /translation="MYLKKLSKLELVIMKFIWNLDIKTNSYEIIDYMKEEHNLPEKVA
                     LKILSKLSKKRFLYVQETGKCMYYTVAIKEKTYLEFISRNVQNLLKNNFIRNLLVSFH
                     EEELTEEKIKSLENWVVNWEEAYI"
BASE COUNT        11605 a         3228 c         5213 g        10433 t
ORIGIN      
        1 agtaaagtat aaaattctat tactataata aaagatagaa ctagaagtct ttatgaaagt
       61 gggaaaagta tttatataaa taaatttata tggtttatag tttaacagta ggaaatatcg
      121 tatgagtgag aatatcgtat tttacataaa gatttagcaa tatgacacac tgttgtcgtg
      181 ttctgtagga tatgattaat aaatcagata tgaaaggaga gtgagtaata tgccagaatt
      241 actaaaaaat atgtataatc gtgagtcact ttatgaagtt gcagtagcta tccaatcagt
      301 ttacaactca tttaaggtag acgagttcat aaaatctaca atggatgaga catggaataa
      361 cttagaatta aaagccagat gtcgaaagat aagtatgagt ttaggaatgt atttaccaga
      421 agactataag gaagctcttt ccattcttga aaaatcagtt acaggttttt attttgcttt
      481 tttctttcca gattttgttg aagtttatgg gcaggacgaa ataaattggg atttatctat
      541 aagtgcatta gaaagaaata ctgagtattg gtcttcagaa tttgctgtaa gagcatttat
      601 catcaaggat gaagagcgta tgatggcaca gatgcgtaaa tggtctaagc ataagagcga
      661 acatgtacga agacttgcaa gtgaaggttg tcgtccccag ttgccttggg gacaagcaat
      721 atccaaattt aaaaaagacc ctacacctgt actgcctata ttggagcaac ttaaaacaga
      781 tacatcaacg tatgtacaaa agagtgttgc taataatcta aatgatatct caaaaacaca
      841 tccagattta gtcataagca ttgcaaagga ttggtacggt aaaaataaat ctactaactg
      901 gattgtaaag catggttgta gaactctact aaaaaaaggc aatcgtgatg tattagccct
      961 ttttggatat gatgatacta cttctataaa tcttcaggac tttactttag aaacaacgtc
     1021 tatttctatt ggagaggatt taactttttc atttaatatt ttagcaaaaa aagcgacaaa
     1081 aacaaggctc gagtacggaa ttgattatat gaaatctaat ggaaaaagga ataggaagat
     1141 atttaaaata tcggaggttt cattaaaaga aaatgagaaa aagtcatata tgaaaaaaca
     1201 ttcatttgca gatgtaagtg taaggagaca ttatccaggt atccactcga ttactattat
     1261 tattaatggg gtagaaaaag gcaaacttga ttttgaatta ggtgtataat tttactaaca
     1321 gcataaccta tatcagatac tttgctaaac ctatatcgta tactctaata aatctatatt
     1381 aggtagttta ctacttgttt actgaattta aatacaaaga aatacaggtg ttaatccctg
     1441 cccattaaag gaatatgagc ataacacaaa agtagaactt atcaattctg ttacgggtat
     1501 agtagtaaat ccatagaatc acaattagaa gatgaagtgt aaaaaataag ttagtgttga
     1561 ttttagttgc tagtgatatt gaatagttat acaatagcca tataaattag aatttgtaga
     1621 ggagaaatgt aaatggatgt atatagtttt tggaatgaca ctttggcaca agatgctgtt
     1681 aagataagaa aatattttca tgaagatgct tatattaatt ggcatgatac aaatgagcat
     1741 tttactttag aagaatttat tattgcaaat tgtgagtatc ctgataaatg gaatggtaaa
     1801 gtagaaaggg tgctagaatt tggaaattta gtaattacag tgacacatgt ttatgcaata
     1861 aataaaccac tatcatttca tgtcgtttca tttatcagcc ttaaagatga taagattatt
     1921 tctattgatg aatattgggg agaggatgat gatgtgccac agtggagatt agataaacat
     1981 attggaaagc caataaaata gtgtttgttc tgttttataa ctgaaatttt gataacattt
     2041 gatattttga tttgtcattg gtcaacatag tcgttagtgt aataatttaa aaaagtagaa
     2101 tttggagagt gagcactatg gaagaaaaat acatcttatc tgaccgaggt aaagtatatt
     2161 attggataaa agaaagtaat agtgtgtttg caaagaactt aatttttttg ccaggactaa
     2221 cagcaaatca tcatcttttt gatttccaga tacagtactt ttcaaaaaat cataatgtat
     2281 tggtatggga cgctcctgct catggaaaat caagacctta cttagatttc tcatattcta
     2341 acttggtaga agaattgaaa gtaattttag ataaacaaaa tatgaaaaag gttgtactta
     2401 tagggcaatc ggcaggggga tttgtggcac agtcctttat tgtaaaatat ccaaatatgg
     2461 tagaaggatt aatgatgatt ggaacttgtc catatggaac tgactattat agtaagtcag
     2521 atattttctg gttaaaacag actgaatgga tgttaaagtt attcccagat aaattgttgc
     2581 gaaacataat atctaagatg tgtggagcta cgtctgaagg cagaaggagt atgatgaaaa
     2641 tgttagaagg ctacgaaaaa aaagaactgt gtcatctcat gtatctggga tttgctgggt
     2701 tcatgccaga aattcaagac ttaaatatac attgtccagt ttgtttggtg gttggagata
     2761 aagacaagac gggtaaagtg agaaaatata atgagcagtg gcacaataag actgggtatc
     2821 cattgcacat tataaaaaat gcttcacata atgtaaatgt cgataaacct agtgaactaa
     2881 atcagattat ggatatattt attaagcaat taaatatata aaaactacat actcattagg
     2941 taaattatgt agtatatgtg tttacatatg gttatagaaa taaatatgta ataaactact
     3001 taacacttaa aaagtggatt tgtccagagc ataatacaaa gcatgatata taaattttta
     3061 agcgaaatac atcaaaagaa gtattagaat tagtggagat aaaacagcta ttagagatta
     3121 taaataaata gttttaaagg tactacgaat atagaggaag gtaaatcata cgttattcaa
     3181 ggattataaa tgagtagttt aaaagtacta tcggataggt ctctgcatat ttaaacctta
     3241 gtaaaggtag ttaaagtagt agtttaaaaa ctaaaaaatt atataaagga attaggtata
     3301 agaaaatgat tgagagtata ccagcaaaac aaattttaca aaaagtgaaa tttgacaata
     3361 caagatggtt tggaattgac tataatatga atctctatcg tggttgttct catggatgta
     3421 tatattgtga tagccgtagc acaatataca acatagagaa ttttgacaaa gttagatata
     3481 aagaaaatgt gatagagatt ttaagtaaag aattgcgttc aaaaagaaaa aaaggggtag
     3541 taggcattgg agctatgtct gacacatata atccttttga aaagcaactt tgtattacaa
     3601 agcaagcact agatttgatt tcggaaaatc attttggagt gtctattgat actaaaagta
     3661 gtttggtggt tagagatata ccgattttgc agaaaattaa aaaaaataat tctgctattg
     3721 taaagttgac tataaccact gcaaatgatg aattatcaaa gaaaatagaa ccttatgtaa
     3781 atccaagttc tgcacgattt gacgcagtga aagaacttaa tgattctgga attttttgtg
     3841 gcatattatt gactcctatg cttccatttt tgactgataa taaagatgaa atacgagcaa
     3901 ttgtagaaaa agcacacaag gctaatgcaa agtttattta ttgcatgtat ggtgtaacaa
     3961 tgcgtagtgg tcagagagag tttttttatg agcatttaag agatatatca ccaaaattag
     4021 tacttaaata tcagaaaaca tatggtttaa actatgtatg tactatacaa aataaagatt
     4081 cttgtgagaa gttgttaaga gaagaatgtg cacgttatgg tattttgaca gatatgaaag
     4141 agattataaa agcgtacaag aggtcggagt catatattca aataaaattt ttttaagata
     4201 ggctttggat gagatataat agtggtgatt gatgtgttga tattatagtt gattgttaga
     4261 gaggatatta tagatgaata ttaatattga tattctaggt aattgctaga actaatatta
     4321 tagatgaata ttagtattga tattctaggt aattgctaga gttagtatta tagatgaata
     4381 ttagtattga tattctaggt aactgctaga gctaatatta tagatgaata ttagtattga
     4441 tattctaggt aattgctaga gctgatatta tagatgaata ttagtattga tattctaggt
     4501 aattgctaga gctgatatta taatttatta ttaatattaa tattctaggg aattatcact
     4561 atattttaaa aagtaaaaat atatatcaaa atgaactaaa taagtactgt aagaagtttg
     4621 ttaaattaag gtttgaataa agtgagggtg gagaacttat gatagaaata aaaactatag
     4681 aaataaataa aaaaagtcaa attgaccttt taatgttagc cgacccatgt gaagaaatga
     4741 ttgataaata tctcaataaa ggaactatgt acgcattgta tgataataaa gaacttactt
     4801 gtatagcagt tgtaaatgaa atttccaaag aaatatgtga attaaaaaac attgctacat
     4861 atgagcattt tcaaaatatg ggttatgcct caaagatgat ttatcatctt ttagatgttt
     4921 atagtaaaaa atattcatca atggttgttg gtacatctga aagcggagtt cctttttatg
     4981 agaagtttgg atttgtttat tcacataaaa ttaaaaactt ttttgtagat aattatccag
     5041 aaccaatctt tgaaggagaa ttacaatgtg ttgacatgtt gtatctatca tataactttt
     5101 agataggata atatttttag gtagatataa ttaattaatt catataatta tcggaattat
     5161 aatttataaa ttatgtataa taagagtata atttatttag aagctgttat attgtattat
     5221 attcaaataa gatatataat aatttgttta ttttgaattt tggaggatta attatggatt
     5281 caaataataa tactataaaa tcaactgtta aaaagggtat ttcttttggt tcttgtttag
     5341 caatgattat ttcttatact gcatggaaat ctattccatg ggctattttt catggcttaa
     5401 tgagttggat atatgtactt tattattggg ttaagtatgc atagattaaa ttaataaata
     5461 agtatgtaat attgtaaagt ttaagaaaca aaatgtaagg gagtgtctcg aagtgaactt
     5521 tttagtttat aaggcactct tttttgtatt aaataaaata tattttcatt acttaaacaa
     5581 tgaaaaagat gagtatctct attttaatac atacccttat attcattcat ttatcaacaa
     5641 tagttttaaa aagaaagcta tctaaaatct attgtaatct aagtgcttct ctttaaagtc
     5701 ttaactttag taatgatata taagtttata aggttcttat ttcaataatg caaattttac
     5761 ttagaagttc agactttggt atgaagaaat gggtaataat aaaaaagagg tgttgatatg
     5821 aaagaaaaat tagaagaaaa atctaagatt attaaaacat caaaagagta taaacgaact
     5881 ataattgaag aaaaggacag agaatgaacc aaaaaattaa atgacatact tagtagaggt
     5941 gatttttcta atgaaaaatt agataaaatc aaggatttaa ttccaaaaga aatattgact
     6001 agtgaaaatg ttggagaagt tgtaactgaa gatgggtatg ctaagcctga gtatgatgag
     6061 gtatttaaat cattgtttac tttaaataat gattacgatt tacttgcaaa ttttataaat
     6121 gatatcctca aagatgctcc atatgccaat aggaatatca aaccgttcac tcatataaaa
     6181 agaataatta aggctgaaac cgacccaaca attaattaca ttggtgagaa aagacctaga
     6241 ctttatattt tggctgaaga tgaagaaagt aatcatataa atattgagat gcaaagagct
     6301 cttgaagatg attatttgga aagagctgaa tattatctta gtcgtgtaca tggtagaaag
     6361 ttagaagaag gtaaagagta taaagaaatt ggaaaaactg ttggaataca tatactaaat
     6421 catgtaaaat ataatcacat agaagattat gtaaattgcc tgagattaac aatggacggg
     6481 catccaaata tttattctag taaaactgca ttatatttta tagaacttcc aaaaattcgt
     6541 aaatccagtt gtatagcaaa cagagttcta atatggggta aacttattga taatccttct
     6601 catattgata ttagaatact atctaaaaca gattatgtta ttaaaagagc acttgataga
     6661 ttaaaagaat taggcagtaa tgaggactat ttattaaatt taaagagagg tgcgtatatt
     6721 atgaataaaa gtagaaattt taaagaagaa atttttcaag aaggtgttga aaaagggaaa
     6781 agagaagaga aatttaatat catcataaaa ttaaaaaata aaggatataa tttgagtgaa
     6841 atatgtgata ttatagatga tttgaataaa tcagaggttg aaaaaatcta taatcaaaac
     6901 taatactata attgagatgg cactagataa atataaagct tcctctttta aatttaaatt
     6961 aatataaaac cttgttattt aactatagta gatacaaaga gatatataag ctaaggagat
     7021 gattcaaaat aaaagtttga actatctcct tcttatagaa aaacaaaggg gttgatttat
     7081 atatgaaatt ttatactata cagactttag aattttggaa caacaataaa aacaataaat
     7141 atctatcaaa tgattattct tttatattag aagactttga tattccatac aaatggatgt
     7201 atagtcaaat gacaaataga atatatgaat ttgatgatag tatgatatgg gtttggacga
     7261 agagacctga tttaagatgt agtggttatt tagaaaaagg aaaaaaaggt gttttacttg
     7321 aaatagaaat aagtgaagac aatgtgttat tatcagaatt tgatttatgg catttacctt
     7381 taatggatat tactgtagag ctttatgaag atgaacaaat tgaaaagaag gtaagttggg
     7441 aaagaatatt tgacttagaa ctgtgttcaa aattaaatga agttaatata gaagatttga
     7501 cattgcaagg agtgacatct aaagtgcctc tatctaatgt aaaattaata aaagaatttg
     7561 ttgcaaaata atatttttat tgaaatttat tcaaaaaagt tatatattta taacaagagg
     7621 tgttataaat acataacttt ttaaggggga ttttatatgt ctaaacaaca aactggtatt
     7681 aaatcaacac ttatttcaga aatattggga atttcttatt gtattggagc tacattagta
     7741 aataagtatt tttttaaagg aagtagtatt gaatatcttc ctataattat ttgggtatta
     7801 gctatgggag ctcagtgggt ctataataaa aagtatgatg atttaattga tgaggcatca
     7861 aaatgtatac tatcaagagt taatgatatt gcaataaaag tattgttttt ttctgtagct
     7921 atagtatcta tatttcttgt aactttggac ataaatgtgt caaatttaaa tataggaatg
     7981 tctttattag tcattttgtt tattcaatcc ttgttgaagt taattctatt tatatatttt
     8041 gacagaaagg ggatatacaa ttaggtgtca gtattactaa agacaaaaat taaatcctat
     8101 agagaaaaga atcttatgac acaaggtgaa cttgcaaagt cagtaggagt aagacgtgaa
     8161 actattgtac atttagaaaa tggtcgctac aatccttctt taaaactggc aatggatatt
     8221 gctaaggtat ttgatacaac tgtagaagag ttgtttgaat ttattgaaga aaataatatt
     8281 taaatttcat gtattactta tgcattagag aatgaattaa tagataaaaa attcaagttt
     8341 atgtattaga gaatgaatta attataggta aaaaaccaag cttatagatt agagaataaa
     8401 tgacttatag atgaaaaacc aagctcatag attaaagaat gaatgattta tagatgaaaa
     8461 agaaagctta tagattagag aatgaattaa ttataggtaa aaaacaagct aatagattaa
     8521 aaaatgaatg atttatagat taagaagtaa gcttatagat tagagaataa atgacttata
     8581 aataaaaaga aagcttatag attagagaat gaattaatta taggtaaaaa acaagcttat
     8641 agattagaga ataaatgact tataaataaa aaccaagctt atagattaga gaatgaatta
     8701 attataaata aaaaccaagc ttatagataa gaagtccatg cttataagcc agaaaatgaa
     8761 tactttaata gattaaaaaa tacatatttg tgaattatag aatgaataac tccataaact
     8821 agaaaattta taataatatc tatatgaaaa ttagaattat tttatcacaa aaaaattaag
     8881 ttaaataaat atgaaattac ttccaaatat acttccaaaa acatgtaatc gcatatataa
     8941 tataattata aaaataataa atatttttat agtagtagtt aattattaat aaggaggggt
     9001 caaaatgcct agcatgatta tggaagttgt aggagtacta tttatagcta ttggattaat
     9061 cttgacattc attgaaataa aaggaaattt cccttctttt tatggttttg gtcaaaattc
     9121 tatagggaaa aatgctgtag gtattatagc agcaggaatt gctttaattt tctttagaaa
     9181 tggcatagat agcatagatt ctatagctac ttatggtgta tttttagcaa tagaacttgt
     9241 tgtaatagtt gcatatttct taataagaaa aaaatttact aaagaagata aacatttaag
     9301 aactaattaa ctaaattatc tactataaaa ttggaaaatt aaaaacaaat aaaagtttgt
     9361 ttttaattat ttaaaatccc aatttgatta tttttaaaga aactatattc tgtataaaac
     9421 tagaatgtgg tttctttttt atgtataaaa tattttttag caaaagttaa aaggtgtttt
     9481 ataatataaa atagttaatt gtagatgtta ataaaagaaa attatgtata tttcagataa
     9541 agataagaga gtatactata ttttaattat tttttcaata aaacttattg aaaagaactt
     9601 taacttagaa gagtatcacc aaattgcaga tacaatatca taagcagtta tttattgaca
     9661 acccttttta ataaatatat catttgaagt atactgacga aaaggagttg aataataatg
     9721 gacatcttat tggttgaaga tgataagaat attcgagaaa tggtatacga ttttctgatt
     9781 agtgagaatt attttgttaa aactgccgtt gacggaaata cagctattga aatatttaaa
     9841 aattattcat ttgatattat tttactggac ttgatgttac caaagtctag tggttttgaa
     9901 gtattaaaat atatacgaag tgtgagtgtt gttcctgtta ttattactac tgcgaaagat
     9961 agtgacacag ataaaatgct agggcttaat cttggtgcag atgattatat tacaaagcct
    10021 ttttcaatcg tagaattgct tgcaagaatt aaagctaata ttagacgtgc aacggtgtat
    10081 agcagttcaa gaaactctga agatatggtt attcagtata aagatttgat tataaacata
    10141 tcaaaatatg tagtttcaaa gaatggaatt gacttaaact taacacatac agaatttgaa
    10201 attgttaaat tactagcgac taatcaagga cgtgcttttt caaaggaaca attatacaac
    10261 actatttgga aagaacctta ttatggaaat gaaaatgtgc taaatactca tattaacagg
    10321 ttaagaaata aattgtctga tggtatagaa aaaaataatt atattaaaac tctttgggga
    10381 attggctaca aaatggagga agaataatgg agttattttt agttgtaatt tcgattgtac
    10441 tatttgcttt ctacttaaaa gaacgaaata agtcaaagaa aatggaaagt gattataagt
    10501 atatcaattc aagacttcgt gatataacaa atgatgatga aattaattat attttagtac
    10561 catctgatat ttcgattgta aaagaaacag cagtagatat aaataaactt cttgaaaagt
    10621 tttacagtag gcaaattaat tataatagaa gtgaaaaagc gatattgcaa atatttacaa
    10681 acatatcaca cgatttacga actcccatca cagtattaaa gggttatatt gaaatgctat
    10741 atcttcaaag tcaaaaagaa gaattatctt cttcaatgag agcaactttg gaaaaaatgc
    10801 aaacaaattc aaatgagctt gttaattcaa taaataacct gtttaatatg gcaaaaatcc
    10861 aatctggaga tatgatatta aatcttcaaa aatccaatct aacacaatta tgtcatgaga
    10921 ttattttaga gttttatgat ttactagata aagaaaactt taatgttgaa gttaatattg
    10981 aagatagacc tatatatgca aatgttgaca cagaagcatt acaacgtata ctcaaaaatt
    11041 taattgataa tgctataaaa tatggttcag atggtagatt tttagggatt tcactatatg
    11101 aaaaggaaaa acatgttttt atagatattg aggataaagg ttcaggtatt tctgaaactg
    11161 aaaaagagca tattttcaca agagcttata ctgctgacag aaaaaaaggc aatggtttag
    11221 gtttggctat ttctcaaggg cttgcaaact ctatgggagg ttcaatttat gtaaatagta
    11281 gacctaatgt aaaaacagtt tttacggtaa aattgaaaag ttagaaaaaa gttagattta
    11341 aaagagagaa aagataattt tattttgtat actgttttta gaaaggaggg agtatgatga
    11401 actatatcat agagacccat caattaaaga aaatatataa agataaagct gttgttaatg
    11461 atgttaatat tcatgtgaaa aagggagaaa tttatggatt tgttggacca aatggagcag
    11521 gtaaaagtac agtaatgaaa atgttgctaa atctcgttaa gccaaattct ggagaaatag
    11581 ttatgttcag taagaaagtg gcagaaactg attttgaaat attaaaaaag attggtacta
    11641 ttattgaaaa tccttatttc tatgagaatt tgactgctaa acagaatctt gatttacact
    11701 gtgaatatat gggttattat aacaaagaac atatatcaga ggtattggaa tgtgtcggat
    11761 tgtcaaagca atcaaacaag aaagtttcaa aatattcttt agggatgaaa caacgtcttg
    11821 caatagctag agcaattctt actaaaccag aattattgat tcttgatgaa cctataaatg
    11881 cactcgaccc agaggggata agagaaatgc gagaattatt ccgtaagtta aatacagatt
    11941 atggaataac tatatttatt tctagtcata ttctttcaga ggtagaacaa attgcggaca
    12001 ctattggaat tattcaagat ggtaaactta ttaaagaaat ttctatgtca gatatacaca
    12061 aatatcaaac agattatgtt gaagtagatg tagataatgt ggaacttgct ggatacttgt
    12121 tagaaaaaga atttggaata aaagacttta aaattacttc ggaaagttgt attgaaatat
    12181 atgatttacg aaaagatgta aaagaaatat ccaaaatatt tatcaaaaat caaattggta
    12241 taaatagcat tggacgtaaa caaagttctt tagaagatta cttcttccaa actacaggta
    12301 caggaggtat agaaacacta tgatacattt aatgaaacta gaattaaaaa aagttgggct
    12361 aaaaagatat tttttatttt caatactggg gattttgtta tgtatgtttt ttgtctttac
    12421 tggattgaat gataaatcta cttcaatata tgattatgat gttacattta ggacaatcag
    12481 tttagttttc tgtttttact atattatatt atttgctgtg ttgaatgtgg catatataat
    12541 aaatgaatat acaaataaaa caatcttgat tttattctct tatccacttg accgtaaaaa
    12601 acttatttta tcaaagttac ttttgattac gactcttatg atatcatcaa tgatagttgg
    12661 atatatctgt tgttttacat tcgttgttgt gttggataag tattttaatt tagttattgg
    12721 agattttcat atttcaattt tatcttattg gataccagga gcaattaaaa gtattattgt
    12781 attttgctca ttaggtatat ggacattcgt tgttggaatg ataagaaaat caatacctgt
    12841 tacccttgtc agttcaatta tttttatcaa tttaagacaa tttattttag ctggtacaaa
    12901 tacaactcaa gacagtctga tttctgtttt tattatagtt ggaataactg tgattggtat
    12961 atattatata ctaaatcata aagttactga aattgactag atactgtgga taggaaggta
    13021 gttattaatt gtatcttctt gggataataa tgatttgcta ttatatcagc tattattaat
    13081 attattagag ttttaataat attaataata gctatatatt ttttcttctt atttataaat
    13141 ttaatgattt atagtcataa aatgaactct aagaagagat aaaaatgcgt tttatatgtt
    13201 tttagattaa tatgaaatat cacaatgaaa tgttgtacaa agtgatatat aataattata
    13261 tgaactataa aattgactaa acttattgac taataaatta gatgaaaagt tgagacttac
    13321 tgaaaataaa tacaatgaaa tatatactac aagtattaaa ttaaatctga actttacata
    13381 ctattagaat aagtattata agattataat gatttaaaaa tattaaaata attgaggtga
    13441 taacatgaac aattcctttt tagataaatt gattgagaca aaagaactta aaaattcact
    13501 ttataatgtg ttaaaacaca attttcttta tcattctaat aagatagagg gcagtacttt
    13561 tactactgaa gcattagcac ttttactcga taagaatgtt gttacaggaa gacatacttt
    13621 agatgatgta caagaaactg ttaattctag ttatgtattt gatacagtaa ttgactcact
    13681 gaaagagaaa ataacacata atttcttaag gaatctacat tcaagtttaa tcttcaatac
    13741 aaccctacat tccagaggga tggctggtat atataaaact atacccaata tgatactagg
    13801 aactgatgta agcatagcac aaccatttga agttgagcca aagcttgatg aattaattga
    13861 atggtactat agtcagagtg aagtgtctat taaagttata gctgaatttc attatagatt
    13921 tgaattgata catccatttc aagatggtaa tggtcgcata ggtagatttg ttatgctaaa
    13981 acagatgtta gaaaataatc ttcctataaa aattgtatct tgggatagtg aggacttgta
    14041 tagaaactcc ttaaattctt gtagtttagg taattatgtc cctttaattg aatatttatc
    14101 aagtttagaa gattttagag aagtatataa aatgttatgg aaataattgt ttgtagcaaa
    14161 aaaagttttt atataaatat atttttaact atgctattta acgttgattt cttagttatt
    14221 cttagcttgg actataccca ctattttaac tatataaaat agtggatata gtttaactat
    14281 ctctttataa ctatttttat gtatcttagt tgtttcttaa tattgggaca gttcataaaa
    14341 ctaaaagtga tttttaattt tatcatttat aatttaccat tacatcagaa aaatgcttat
    14401 cattagaatt ttcataaaag gtacctattt tcttcaatta actaaatcaa ttctattagt
    14461 cttaatcttt cgtatttcaa attgataata caagaaaata aaaaataaaa aattttaaat
    14521 tttttattta ttgcgaaaaa aataaaaagg tgctatactt tttgtaacat attattcaaa
    14581 ttattaagag atagtaaata tttatagttt aatttgtagt acactagcat gatttgcaga
    14641 acaatgaatt aatctatagt ataatagttt aatttgaagt acaacgattt aatctatagt
    14701 acactagcat gatttgaagt ataacgattt aatctatagt acaataactt gatttgcaat
    14761 acaataattt aatctatagt ataatagcat gatttgaagt ataacgattt aatctatagt
    14821 acaataactt gatttgaagt acaacgattt aatctatagt acaataactt gatttgcaat
    14881 acaatgattt aatctatagt ataatagcat gatttacagt acaataattt aaattgtagt
    14941 acaaaagtac tatcaaataa gaatttctac tttaaaaata ttactaaaag taattaaaat
    15001 ccaataattc aatataatat ggcaaaagaa tagaaataag gtgagagtag tgaaagtaaa
    15061 gtcaaattta gatgaaattt tatatcataa gattattgaa agtcttattc gtggtgaata
    15121 ctctgtaggt caaaaaatat tactaaatga cctttgtgaa aaatttgaag taagcagaac
    15181 accagttgta caagcagtaa aaatgctaaa taaagatgga gtgcttacta ttatgacaaa
    15241 tggtaaagtg tacgtaccag agtatgaata tgatatggta aaacaagttt gtgaaacgag
    15301 aacactgatt gaaacatatg ctttagaaaa aatgatgcaa gaagaggaag aggtttttca
    15361 acaaaagcta gatgtaataa aaagatactc tgataaatgc gaggagtact atcgtcaaga
    15421 aaaatctgta gaacttgcac tagcagattt ggaattacat aaagccattg tagaaggggc
    15481 aaataatgag attttaaatg atgtatatgt tggtatacaa ggaagattta tagtagtgaa
    15541 ctatttaatt cgaccattaa aaaatcgtaa ttatgaagga acagtacaag accattttga
    15601 aatattaaaa ttcattgaag acagagatac aaaaaaagca gtagataaac taagaaatca
    15661 tattcaagga actattaaaa gattctgtga agatgaataa taagttttga agttactata
    15721 tacttatcta ttaagttgct aaatgtagtc taagtataat ctaattatag tttaaacata
    15781 atctaaatat aatctaaata tagtgtaaat aagtctaagt atgaattaaa tatagattaa
    15841 gtatgaatta agcatggatt aaatatactt taaattacaa atattacaag gaagccagaa
    15901 ggcttcctaa aaaaataacc tttataaaat tttttatttt aaatttaaaa ttttttattt
    15961 taaatttaaa ataaaaaatg aaagaggtgg tagagagttt gaaaaaaatt actaaagaaa
    16021 ggatagaaaa tactatgaaa aagctattta cgagcgaaac atttttggaa tatcaattta
    16081 taagtgattg ccaaatatca ccagatggag gatatacagc atttattgta aaaaaagctg
    16141 atatcaaaga gaatggttac acaagccaag tttatatatt aaacaataaa actggcgaat
    16201 taaaacaaat aacgtctata aactctgttg gagcatatgt ctgggaagat gaaaatacta
    16261 tcttgttccc tgctttgcga aatgaaaaag taaaagaagc tgtcaaaaac ggtaagcaat
    16321 gcatgagtta ctatgcttta tctttaaatg gtggagaagc agaagaactt tttagactcc
    16381 ctatcaaagg tggtaaattg aatcctatag gaaaaggttt gtatgcagtt attgattctt
    16441 atgacaatga ccgacctatt gtagagggat tgccagaaga agaacaacag aaaaaaataa
    16501 atgcttataa caaaagacat tatgaacatt tcaaagaaat tccttatgct gtcaatgggg
    16561 agggatatat tagcagaaaa agaaaacgcc tatatatata cgacagtaat ataaataagt
    16621 tgaaggcaat tacagcacct atgtttaatg ttgtaggtat gaaaataagt gatggaaaaa
    16681 tcttatatat agggcaagag tttaaagatg taaaaggttt gaaaaatggg gtctatgtat
    16741 ttgatacaaa cacaaacaca aatatctgta tattagaaaa agataagtat attataaaag
    16801 gttttgaatt atatcaaaat caagtgatac taaacctaac tgatgcttta tcttatggaa
    16861 atggagaaaa tggagatttt tatactattg atattgatac gaaagaaatg aaacttcttt
    16921 cagggcatca acatcattgt attggaaata cagtaacatc tgatgttaaa atgggtgctg
    16981 gtcagacaac aaaggtagat ggagaatata tttattacac ttctacagta gatatggact
    17041 gcattattga aagaatacat attccaacag gaaaacagga aaaagtaaca cagacaggtt
    17101 cagttgattt tatagatgta aaagatggca atattgtatg tgtgggttgt ttaggaaatg
    17161 gattaccaga agtttataca gtagagaatg gaacattgtg taagaaaaca catttaaatg
    17221 accatatttt agaggaatat aaaatttctg tgccagaata catagagtca aaaggaagtt
    17281 ctaaatggga aatacaagga tacgtatata aaccagtaga ttatgaggtg gggaaaaaat
    17341 atccagctgt attggcgatt catggaggac caagattgac atatggacca tattttatgc
    17401 atgagataca ggtatttaca agtgcaggtt actttgtatt cttctgtaac ccaagggggt
    17461 ctgaaggtcg tggcaatgct tttgcagata ttaggaaaca gtttggagat attgattata
    17521 tagattttat ggaatttaca gatactgtac ttgaaaaata tacagacatt gataaaacaa
    17581 aattggctgt tgaaggtgga agttatggtg gatttatgac gaattggata attggtcata
    17641 caaaccgttt tgctgttgct tgtgctcagc gttctattgc aaactggagt agcatggagg
    17701 gtacaacaga cattggttat tatttctgca aaggacaaac aggtgcttct catatggaaa
    17761 accacgagct tcaatggaaa cagtcacctc ttgcttatgc tgataaatgt gttacaccga
    17821 ctttattttt acatggtgaa aaagactata gatgctatat gcaagaagca ttccagatgt
    17881 tttcagcatt gaaaattcat gggtgtccta caaaactttg tctatttgaa ggggaaaacc
    17941 atgaactgtc tcgttctggt agaccaaaac aaaagctaca aagattagtt gaaatgctag
    18001 attggttttc tgtgtacata aaaaaagata acataggaca gtagaaagga gaatataaaa
    18061 atggaaaaaa taaagattga aagttcagat atttttgaat atatattccc tcatgatatt
    18121 tcttgttcac ctgatggaaa gcatattgct tatattatat caaatatcaa cgaggaaaaa
    18181 gactgctatg aacatgactt atatgtgatg gacatcaaaa cagaaaaaca aatacatatg
    18241 actcaaacaa aagatgtaac atcatttagt tggatttcta atacagaact actttttaca
    18301 tctaaaagaa ataagccaaa agcaggtaca acagattttt acactatttc tatagaagga
    18361 ggagaagcaa aagaagcatt ttctattcca aaagcttgta gcgtacctgt atcacttgga
    18421 aataaattgt ggttattgac aacaaaaaat ccaacggatt ctaaaaaatc agaaccagat
    18481 agggcagtag agggtgtaga ttattggaca tttacagata aaccttttat aagagataga
    18541 gaaaattttt ctcaaagaag acgtgtaaca ttagaattat atcaagaagg tgaaaatata
    18601 acaaaagcca ttacaccaaa attttgtgaa gtagcaggta tagacgtttc ttctgataaa
    18661 aacagaattt tatatactgg tcagatttat gaagattgtg caactccttt ttctggactt
    18721 tgggagtatc atatagacag tggtgaaacc aaagaacttg taccacaagg aaagtaccaa
    18781 ataagtttgg caaaatatat tggcaaagat aaagtaatgt tgcaagcttc aacattagaa
    18841 cgttctatca cacagaatca tgatattttt atacttgatt tgagtactag tgaaataaat
    18901 atgattgcta gtccagatgg tatgtatgct acattactgg atgtagatgc agtatatggt
    18961 ggtggacgta gtaataaagt tataggagat aaatttattg gtgcaagaat ttgcagaact
    19021 atgacagaat ttaatgagtt tgatacaaag acaggtaata tacgtatcat cacaaaagta
    19081 gatgctttta catcttttga tatttacgac aacaccatgt acacagtaat gttgaaagat
    19141 tatgagttag cagaaatata tagcattgat atgactacag gtacaatgaa aaaaatgact
    19201 gctttttcta aaccatattt agatactcat aaggtttcat tacctgaaaa attgacgttt
    19261 gtagcaaaaa ataaagaaga agttgatggt tttgttatac cacctataga tgctaaagaa
    19321 ggcgaaaaat atcctgctgt attgttcatt catggtggac ctaaatgggc atatggctat
    19381 atgtttacac acttgaagca gtgtgtaaca tcaaagggaa tgtatgtgat ttattgtaac
    19441 cctcatggtg gtgacggtta tggtgaaaaa ttcttagaaa tggtagaaag atgggggtat
    19501 gttgactatg agcatcttat ggaatttgta gatacttgta ttgaaaaata tcctgggatt
    19561 gatgcagacc gcttaggggt tgcaggggga agttacggtg gttatatgac aaactggata
    19621 attggccata cagaccgttt caaagcagca gtttctcaaa gaggtattag taacttgatt
    19681 acagcttctt taattattga ctttggggat agaattatga agcagacttg tggagataag
    19741 acgccttgga atcatgagga ggttctttgg aatcattcac ctattaaata tgtgaaaaat
    19801 gttaagacac caacattgtt cttacatagt gatagggatt atagatgttt tatgggggat
    19861 actttccaaa tgtttacagc attaaaacag cttggtgtag atacagaaat gtatttgttc
    19921 catggagata cacatggatt gtctagaaat ggaagaccat ctaatagaat tgcacgagca
    19981 aatgctattg tagattggtt tgaaagatat ttataataag ggggttattc tatgagtgat
    20041 atgttattat ggtttagtgt cgtattagtt ttatttgcta ttggggattt aattgcaagc
    20101 aaaacaaaag caaaagtatc agctgtattt gttacactac ttttattttt gattctattt
    20161 gtcacaaaag caataccagc tgatattatt gaaaaagcag gtatgaccgc agcagctagt
    20221 tggagtgttc caatgattat gtttagtatg ggaacaatgt tgaatgttaa acaatttata
    20281 gacgaatgga gaacagtatt gacagcatgg cttggaattg tagcagttat agtctgtgtc
    20341 tcattatgta ttcctttgtt tggaaaatca acagtattga caagcatacc agttataaat
    20401 ggagctttac ctgctactac tattatgaca caagcagcac tagaaaaagg actgacactt
    20461 gcagcagcta cagcaacagt tgtatttgca attcagaagt ttattggtac accaatagct
    20521 tcaagagcag cgttacaaga ggcaaaccgt cttttagtag aatatcatga agcaaaatca
    20581 aaaggcattg atttagcaaa tgttgatact gataagaaag aagcagagaa tacaggcaca
    20641 aaagtaaaac aagctttctg tgaaaaatac gataaatatt attctacaaa tgtttgtata
    20701 ttttttatag cactattctc ttatctaggg tatgaacttt cagagattat tcatgtaaat
    20761 tattctattg tatgtcttgt tgttggtgtt attgtaacac gtattggtat tgtaccaaaa
    20821 gacattttgg aaaaaggaaa aatcaaggga tttattaaca tggttgtgtt tgcagctgtt
    20881 attccttctt tagcaaaagt ttctttgaca gatttaatta gtctttttgt accaattgtg
    20941 ggtatgtttg cagcttctat cattggtata ttccttatga tgaaggtgtt accaggttgg
    21001 aaaattatcg gttctaaacc tcttgctttt ggagtagggt tttgtcagat gttgggattc
    21061 ccaactacat atttaatttc aaatgaagtg tgtaatgctg ttggagaaac ggaagaagaa
    21121 agagcatatt tgatgtctaa gattatgcct aagctggtag ttggtggtat ggcttgtatg
    21181 atttctattg tagtagctgg tcttatggta ccaatgttgt agataggttt catagttaaa
    21241 aagtggtgtt aatttatagg agaagctaaa aagtagtatt aatttataaa ataattttat
    21301 attagttaat ttgttataag aatattttct ttttatgatt ataattttga ttttataaga
    21361 gagcagattt tttatttgct atgctaatag ttataatttg tttttatttg ctaaaatgca
    21421 actttaattt gatttatgta taatataggg tatttaataa tatttttgaa gaatttttat
    21481 aaaaaattaa aaagaggaga aaaaagggag tgccacaaag tgaacttttt agttctaagg
    21541 cactcttttt tgtacgaaat cgaatatatt ttcaacgttt taaaagtgag aaagagactt
    21601 atctctagtt tgggatagcc aaatttaatt attaaaatta ttttttgttt tatttatcaa
    21661 agagtattcg tgttttagaa gttagtattt tttattttat atatccaagg ttttccgttt
    21721 ctaatgtttt cttttttaaa ataattaggg tattcaatta tagtaaaagg tggatggtat
    21781 tttggaatga tattatttaa agcacagtat tgaatgttga aatcctcaca ttttagagta
    21841 ttatcttttg taatcaaaaa aatcttctat acttatagca aggttacttc tgcaaatatt
    21901 ccatgcatca taatatccaa atttaaattt ttttaatata gagtttacct ctagtctaca
    21961 ctcttgaata actctttcct ctatccaaat tcttataaac tcatcccatt tattactatc
    22021 tatttattac tatctaaatt ttttagtatg tttgtaattg gaaatggatt tattccttta
    22081 tgttttttat aaatagttta taacttaatt tattattaaa caaatcattc atacagaatt
    22141 actttttctt ttagatattc aattcttact tttaataaat atttaataca ttctatctta
    22201 tgtggtttta aaaagtgttt atggctatca ataatctcta atatttcatt catatttatt
    22261 ttgtcatagt aatattttac atcttttata ttgacaaaaa agtgctctaa gtgtatagtg
    22321 tgtatataat aacatcacac tggaggtgat aaaaaatgaa agtgctcatt tctaacacat
    22381 cagataagcc attataccaa caaattaaag agcaaattaa agaagcaata tttactgaag
    22441 aactgaaaga aggggatgca atgccctcaa taagaaattt tgctaatgat ttaaaagtta
    22501 gtattttgac tattagacga gtgtatgaag aacttgaaaa tgaaggtttt cttacacgcc
    22561 aagttggaat aggaacattt gtttcaactg gaaatttaga aatactaaga gactcaaaga
    22621 ggcgtatagt tgaacaaaaa atggcagata tgattaagga tgcaaaagca ctaggaatta
    22681 cacagataga gttacaagaa atgatgggta ttctatatga ggaggattaa tatggaaaat
    22741 attttagaag tttataactt aaataagact tataccaatt tttcattatc taatataagc
    22801 tttgtattac cagaagattg tataactgga tttataggtg ttaatggagc aggaaaaaca
    22861 acaacaattc gttcgatatt ggatgtcgta aagcgtgata gtggaaaaat aaaaatcttt
    22921 ggtaaagatt tcgatggaaa tgagaaggaa ttaaaaaatc gaattggagt tgtatttgat
    22981 gattcatatt tctatgagga gttgtcaatg tcagaaatga aaagtattat tgcaccttca
    23041 tatgataatt ggtgtgaaga agattatcaa caaaatatga agcgttttaa tcttaatcca
    23101 aaacaaaaga ttgatacact ttcaaaagga atgaaaatga aatttgcttt agcattagca
    23161 ttatcgcata aagctgagtt tttaattatg gatgagccta caagtggttt agacccacta
    23221 atccgtagtc agatacttga catactaaca gaatatatga agaaatgtgg tcgtggtgtt
    23281 ttcttttcta ctcatataac atctgattta gacaaaatag cagatatgat tgttatgatt
    23341 gacaatggac gtattatatt agagcgtgaa aaagatactc tattggatga acatagaaaa
    23401 gtaaaagggg atattcaatt tctaaatgat gaaatcaaaa aattattttt aaatttagaa
    23461 attacaggtt atggttttat agggattacc tcaaaaatta atgaagtgca aaaaaatatg
    23521 ccagatattt taatagagcg tcctacaatt gaagatatta tgcttgcata tattgaaagg
    23581 agagagtaat tatgttgatt catttagtta aaaaagatat tctgattgta aaaaaatatg
    23641 tattgttgat attgtttatt gcaataggaa tcccattatt tatattatgg cgtttacctc
    23701 catttgcaca aatattggga tttgtactat caattatatt ttcagaattt atgctgtgcc
    23761 agtatctatt attaaaggag agtcaatatt caaaagcatc tgtattactt tgttcaactc
    23821 cttatcctag acgtggctta gttcaatcta agtatgtttt atttgcaatg gtatttatct
    23881 attgtacatt agtttactgg attgaaaatt tacttattcc acaaatagga acttttgact
    23941 taacatatat tttgattgtt ttattaataa gttctattat ttatggagtt tatatgccta
    24001 ttcaatacaa attaggatat gaaacaacaa aattcttttt cgtgatgata atcatggctt
    24061 catcatttgt attaccatta actatagctc acagcaattt tgaaattcca tttatatatc
    24121 agtatccatc catgatagtg aatattgtat tgttcctttt aagtttaatt atactgttag
    24181 cttcaatgtt tatttctatt aaaattttta gtaataagga gcttgtataa ggtaaggggg
    24241 aattttatat gccacatttg ccagattggg ctgttttact ttgtatctta cttccaatag
    24301 tatataaagc ttgtcagata tttaaaagta aaaaatagag tacatattta tattgccatt
    24361 tttattgagt gaagttagat ggtatgaatt taaaaggtta cttgaaaata aagttacttg
    24421 gtgtgggaga gtaacatcat aatattatag attatatgtt tcttgtgaat caatttgtat
    24481 tttttaatag ataatatcca gtaattttat tttccattga ttattttcaa ttatgagtat
    24541 gattgtgtgt attgtatacc atcttttaag gtgtttttaa aaaattatat cgtcaaaata
    24601 taaatctaag gaatcctata aataaagctt ttcaatttta gaaaactaat aaaaagtagg
    24661 aagttaataa aaagaagctg tctcaaaata gagataagct tctttttcat tgctgaaatg
    24721 acgaaaatat aattgattta atataaaaaa gagtgcttta tgaactattt attttgaaca
    24781 gtagatacac ttgcactcaa tttagttact cctaagcttt atgaactaaa agtttatttt
    24841 gaagcctatt tttctaaata atcatctata tacagtattg cgtttctttt atttattcat
    24901 aatttatttt cttattaaag tttttctata ttactttact tttaatttta tacgaattat
    24961 caaaaataaa atagttatta gaaaaaaata aaagtaattg caaagattgc aattacttac
    25021 ttctatatta attactatac cataaaataa caaaaaaatc aagtcgagta atccttcaac
    25081 ttaagtgata tactaggtat taataatttt taattaataa aatataacta gaggaaaatc
    25141 tacattttct caatttcttt aattaaattg acctctaatt aagtaattat aaggagaaaa
    25201 attatgaatt tagcaaaggg attagatgtt ttaaaaattt catcaaatgt attcggtgaa
    25261 gataaagtta tgtatattcc tgtaatctac acagaagatg atgcaacact tattgacaca
    25321 ggtcttccgg gtcaaggtga tttaataatt gatgctctta ataaaagtaa cacgagcttt
    25381 gataggttaa aaaatataat aattactcat catgatatag accatatagg aaacataaat
    25441 tatctaagag aaaaatctaa gaataatatc aaagtatatg catacaaaag tgaagtcagt
    25501 tatataacag gagaagaaac tccttttaaa ctttatatgt tggaacaaat ggtagataaa
    25561 attgatgata agatgcttag tatgctaaat gttatggtac ttggatttaa atcatcatat
    25621 actaaagtag atgtgtcatt agataaccat gaaaaattga atctaggtga ggaaatagaa
    25681 gttatacata caggaggtca cactagaggt cacatatgtc tttatttaaa agagtctaaa
    25741 gtacttattg ctggagattt gttacaggta gaaaatggag aacttacgcc tgttgatgta
    25801 atgcacagca acaaacaaga gttaaaagat gctattaaaa atataagtaa ttatgatata
    25861 gaaacgatag tttttagtca tggtggatta tatcaaagag acataattgg aacattgaaa
    25921 aacctaatta ttgagtagta ctatatgatt tacaataatt tcttaaatta cttaaaatta
    25981 tatctaaaga tgtagaatca aaattaaata taagtaataa gaattttgct ttaaaattat
    26041 acttaagtgt taagtatgat acgtagtatt acaagtattt tagaatataa ttttttatag
    26101 taattttaag gttctacaat acttcagttg aaaaatattt aacagcatag tataatagga
    26161 aagaaaatat tttaaataaa ctttagtata caaagtgaag aaaaatattt aaattatata
    26221 taatattgta gagtgaggta aaatatttaa gttatatatc ataatacaga gtgaagaaaa
    26281 atatttagat aatgtaccat aatacaaggt gagtaaaaat atttaaagca tgtataataa
    26341 tgcaaagcga agaaaaatat ttaaataatg taccataatg cagagtgagt aaaaatattt
    26401 aaataatgtg ttataataca aagcgaataa gattatttaa agcatgtatt ataatataaa
    26461 gtgagtaaaa atatttaaat catgtatcat aatataagca gagtgaagaa aaatatttaa
    26521 ataatatatc ataatgtaga gtgaggtaaa atatttaagt tatgtatcat aatacaaagt
    26581 aaagaaaatc atttaaatta tatatcataa aaataatatg aaatattgaa cactcataat
    26641 attggaggct ttaatatttt aattgatagg ttacattatt tataacatta aaaatacaat
    26701 ttacataaaa tagacatatg aaaaataaaa aattatataa taattatggg aatgaggttc
    26761 tcccttggat gataatatcc taaactgcca atgagctgat gacttctatg atatcataga
    26821 tgccaccagc tttttttgtt gtttaaatcg ataaaatgga ggtgaattac ttactaaatt
    26881 tttatttttt aaatttgaag aaatatttaa ttaatagaaa aaacagtaga ttatatgtta
    26941 attattttat taagaatggg ttaagagtat acctatatcc tatcaattta aaaaacaatt
    27001 atgatagtca ttacattgac tacagttgat gcaataaaac tttcaaaaaa tcttatgatg
    27061 caaatagaaa ggaattaaaa tgatagaaaa atttaaaact ttaatatgga ttaaaatgat
    27121 aataagaatt aaaagcgttt ataaaacata tggtggacta tttttgttag gactcatagg
    27181 tataccagtt ggtgcaatta taggtcttat agacaccata tttggaacgg ttcttctaaa
    27241 agttacagat attcgagaaa catatccaat gtatctgata ccatttttag cagtagtagg
    27301 agttgttatt gcttattgct attttaaatt tggaggaaaa agtagtaaag gaatgaatct
    27361 aatatttgag gtagggcatg gagaagaaga aattattcct ttaagattgg ttccatttat
    27421 aatatcaggt acatggttaa cccatttatt tggtggtagt gcaggacgag aaggagttgc
    27481 tgttcagatt ggtgcaactt tttcacattg ggtaggtaaa aggttgccta taaaaaatgc
    27541 ttctagtatt tttctagtaa ctggtatagc agctggtttt gcaggattat ttgagacacc
    27601 aatagcagca atactatttg ctatggaggt tttggtagct ggttcactgg agtatcaatc
    27661 gctttttcct gcgtttactg cttcttttac agcaagtgca gtatcaaaaa ctttagggtt
    27721 agagaaattt tcttttgcac tttcttctaa agttgtattt gacttaccaa tattttggaa
    27781 gcttattgtt ttaggaatta tttttggaat ggttggtgga gcatttgcat ggtgcctgaa
    27841 attgtcaaaa agaaaaatag gtaatagatt aaaaaatcct atgataagga ttgctattat
    27901 tggagtatgt cttagtgtat tattcctttt attttataaa ggaagatatt caggtttagg
    27961 gacaaattta attcaaaata gtttttatgg tggagaaatt tattcatttg actggctgtt
    28021 aaagtttata cttacaatac tgactttgtc agcaggtttt caaggaggag aggttacacc
    28081 tttgttttcc attggagcta gtcttggtgt attgttagca ggatttttta atttgccaat
    28141 tgaattagtt gcagcgcttg gctatgctag cgtctttggc agtgctacaa atactttttt
    28201 tgctcctgta tttatagggg cagaagtttt tggatacagc tatttacctt atttctttgt
    28261 agtatgcgct atttcatata tatttaatat ggataaatct atttattcac tacaaaaaat
    28321 ttcaacgaaa caataaataa aacaacataa tgtatgatta taagagaaag aatattagag
    28381 aaaggatagg gtaggaatat gttgacaagt ttagctttga tttttttatt aggaatggcc
    28441 tcgggaggta tttttgagaa gataaaatta cctagcttat tgggaatgtt acttacagga
    28501 atcatattgg gttcatatgt tttaaatttg attgataatt caatactaga tatttcttct
    28561 gaccttagaa agattgcatt gattattata ttaacaaggg ctggattatc tttagatata
    28621 aacgatttga agaaagtggg aagacctgct gtacttatgt gctttattcc agctactttt
    28681 gaaattatcg gaatgatagt tttagcacca aaattactag gcgtttctat attggaagca
    28741 gcagtcatgg gtgcagtagt aggagcagtt tctcccgcaa ttattgtacc taaaatgctt
    28801 aaattaatgg aagaaggtta tggtacagaa aaaagtattc cacagatgct tttagcagga
    28861 acttctatag acgatatttt cgtaattgtg atgtttacag tattcacagg attggcacaa
    28921 ggaaatagta tatcagctat tagtttttta caaattccag tatcaattat attaggtgta
    28981 atagttggag cagtgattgg aatctgttta gcagtatttt ttaagaaggt tcatatgaga
    29041 gattctgcta aaggggtgtt gcttttaagt atctcatttt taatgataag tttggagact
    29101 gctttagagg gtattgtgcc attttctgga ttattagcag ttatgaatat tgggattttc
    29161 cttcagataa aatatcgtgt agttgcaaga agattgtctg taaagtattc aaaactatgg
    29221 gttggtgctg aaattctctt gtttgttttg gtaggggcaa cagtagatat aagttatgca
    29281 tttaaagcag gaattggagc tgtaatttta atatttggag ttcttttatt ccgtatggta
    29341 ggagtattct tctgccttat taagacaaat ttgacaataa aagaaagatt gttctgtatg
    29401 attggctata ttccaaaggc tacagtacag gcagcaatag gaggtgtacc acttgcaatg
    29461 gggatagcat ctggacaact tattttgaca ttagcggttc tcgctatact tataactgca
    29521 cctcttggag cttttggaat tgatgtaact tataaaaaat tattaacttc tgtagaaggt
    29581 aagagtaagt aagaataaaa ataaagatta ttttaagtga taaattatat tttggaaaaa
    29641 actatattat tgagtacaat gttagaaaat catttgagtg attacagaag gtagaagttt
    29701 atatcggatt ttaaggcatg tgatgattat tagaattgat tttgtgaaat tgttattgta
    29761 atatttaatt atatagataa agaagcggag tgataactat gtatttaaaa aaattatcaa
    29821 aattagagtt agttattatg aaatttattt ggaatttaga tataaaaacc aattcatatg
    29881 agattattga ttatatgaaa gaagagcata atttaccaga aaaagtggct ttaaaaattt
    29941 tatcaaaatt atcaaagaaa agattcttat atgttcaaga aacaggcaag tgtatgtatt
    30001 atacagttgc aataaaagaa aagacatatt tagagtttat atcaagaaat gtgcaaaatc
    30061 ttttgaagaa taattttata aggaatttat tagtatcatt tcacgaagag gagctaacag
    30121 aggaaaagat aaagtcgtta gaaaactggg tagtaaattg ggaagaagct tatatataaa
    30181 tgttattatt tttattacaa tttagataat tttggttttg taagctctgc aactattttt
    30241 agatggttgc agagcttatt tttatttttt attcccttaa gcaatactta aaagtaaacg
    30301 catttatatt tactaacttc aatcacttct aatacttaga ttacttttta aaaatatttt
    30361 gatatgtcat ctctatagta atctagaact tgtttctatt ctttatataa agtttttatg
    30421 aatgatatat ataatattcg ttcatttgat taaaaataac aaaatattaa ataattcta
//
LOCUS       DAMJYN010000043        29654 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.044, whole genome shotgun sequence.
ACCESSION   DAMJYN010000043 DAMJYN010000000
VERSION     DAMJYN010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 29654)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29654)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29654
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.044"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(151..2121)
                     /gene="ftsH"
                     /locus_tag="PC466_002133"
     CDS             complement(151..2121)
                     /gene="ftsH"
                     /locus_tag="PC466_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HDF2769515.1"
                     /translation="MNKLLKGAGFYLLVFIIIVGIVQFSGKPTEKIKDLKFSEVYREL
                     TDENISRLYFVNQTSVEGTIKDTNTKFKSYVPTEVMGNKLADEVLDQAKAGKLTFGGE
                     AKPSTPWFVEMLPTLLLIFFMVIIWFVFMNQSQGGGGKVMSFGKSKAKVHKDDEKTRV
                     TFKDVAGLDEEKEDLQEVVDFLKNPKKYIELGARIPKGMLMVGPPGTGKTYLSRAVAG
                     EAGVPFFSISGSDFVEMFVGVGASRVRDLFEQAKKSAPAIIFIDEIDAVGRKRGAGLG
                     GGHDEREQTLNQLLVEMDGFGVNQGIIIMAATNRPDILDPALLRPGRFDRQVVVGTPD
                     VKGREAIFKVHSRNKPLSDDVKMDVLARRTPGFTPADIENLMNEAAILTARKREKKIK
                     METIEEAITKVIAGVAKKSKVISEKERRLTAYHEGGHAVCAHVLEEVSPVHQVTIVPR
                     GRAGGFTMQLPVEDKFYATKNEMKENIVVLLGGRVAEELVLKDVSTGASNDLERVTAT
                     ARSMVTKYGMSSKLGPMSFDSDDEVFLGNSFSSKRNYSEEVAFEIDQETKRIVDGAYD
                     KTRSILQENMDRLEYVAQALLIYETLDAEQFVKAFNKELPLNEIENAVTEENSSKEVE
                     EQLTIKLEKDEEERNNVIDINKNLEDKSDKDK"
     gene            complement(2155..3543)
                     /gene="tilS"
                     /locus_tag="PC466_002134"
     CDS             complement(2155..3543)
                     /gene="tilS"
                     /locus_tag="PC466_002134"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HDF2769516.1"
                     /translation="MIFDKVLSTINKHNLIQKGDKIVLGLSGGPDSVCLLHVLNRLKK
                     DFNIEIYAAHLNHQIRGIEAQKDALYVSKLCEDMGIIFFVKSINVPKYCENEGLSLEE
                     GARKLRYEMFYEIKDKIKANKIAIGHNLNDQAETVMMRIMRGTGLKGLKGIDYIRDNC
                     IIRPILDVERNEIEEYCEAYNLNPRIDKTNLENIYTRNKIRLDLLPYMKDNFNSNVIE
                     SIVRMSNSLKSDNDYIEKEAEAKFREVSNIKEKGFVEINLDDFVCLHDAIKVRVLRNS
                     IKHILGDTNFVDQRHIEDIMSLEDNSKVNKMLTLPRNIFVYRKKDSIILTNEEIVNEE
                     IEFYYNVPSNGFIKIKELKQIIETQVMSIDRYKSMKLDNSSKGFDFNKVKGGIVIRSR
                     RQGDKIKLAMGSKKVKDLFIDLKIPREERCKIPIITDSEGIICVGDYKISENYKIDEN
                     TKEVLKINFNKL"
     gene            complement(3726..4154)
                     /locus_tag="PC466_002135"
     CDS             complement(3726..4154)
                     /locus_tag="PC466_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HDF2769517.1"
                     /translation="MEEKSLSVKISINTRQYDEKGNMDTIEMTAFGKIFYKNDGIYVI
                     YKEKEENIEITNTIKILKNQVSIKKFGAINSTMLFKCGESSTTKYVTPQGTLLIDIDT
                     RELDINIQEGEHIKLKIDYNIKVQDLFLGRNKIDIYIGTK"
     gene            complement(4171..4977)
                     /locus_tag="PC466_002136"
     CDS             complement(4171..4977)
                     /locus_tag="PC466_002136"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HDF2769518.1"
                     /translation="MNNKPIGVFDSGLGGLTVLKEIMKILPNEDIIYFGDTARIPYGS
                     RSKETIIKYTFQAINFLKTKGVKAIVIACNTATARSLKEAQEKYDIPIIGVIEAGART
                     AVSSTKNKIVGIIGTEGTISSKAYNLEISKIDESIEIVNKACPLFVPIVEEGWANTEV
                     AKLTAKIYLQELKEKNIDSLVLGCTHYPILKRTIGEEVGEHIKLVNPAKETAKDLKKI
                     LEVQNIINNTEIHGTYQYYVSDIPEKFSDIAREFLKKKIDKIQKVEIQKY"
     gene            complement(5179..5664)
                     /locus_tag="PC466_002137"
     CDS             complement(5179..5664)
                     /locus_tag="PC466_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase"
                     /protein_id="HDF2769519.1"
                     /translation="MATLLALTFIFMPIKEVFAYEPTENIKKVNKQEKNIAKKEVINL
                     SDNDLMLLSKLVAGEARGESYEGQVAVAAVVINRVLDPRFPDTIEEVIYQKNAFSVVL
                     DGSIKMAPTDSARKAAQEALYGTDPTNKAVYFWNPEIATCKWINRLNPYMRIGNHVFA
                     K"
     gene            complement(5715..6374)
                     /gene="spoIIR"
                     /locus_tag="PC466_002138"
     CDS             complement(5715..6374)
                     /gene="spoIIR"
                     /locus_tag="PC466_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein R"
                     /protein_id="HDF2769520.1"
                     /translation="MRKIKIRLGLLILSLISVISIMTIVINGEVKKVDNISKDYKDKL
                     IRFHVIANSNTDEDQELKLKVRDEVIKYLQPKLQNSKSIKESEAIIKKEYSSLEEISK
                     NIILKNGYNYSVKVGIQYSNFPTKQYSNIVLPAGEYKALKIIIGKGEGKNWWCVMFPP
                     LCFVDESNGVIDKSTDDKLKEVLTDKEYKLIKQDTPKKTSRVKIKFKVLEVVKDLEKK
                     F"
     gene            complement(6519..7199)
                     /locus_tag="PC466_002139"
     CDS             complement(6519..7199)
                     /locus_tag="PC466_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2769521.1"
                     /translation="MENLTKLNLDNYKPLRDVVFENLREAILEGKLKPGQRLMEVQLA
                     EQLGVSRTPVREAIRKLELEGLVVMLPRKGAYVANMSLKDIMDVLEVRASLEGLAAYL
                     AAERISDEDIKKLKDISEEFKKSTLESDVDALLKLDVEFHECIFKATNNKKLIQLINS
                     LWEQVYRFRVTYMSAYDTSHNIVEEHKYLLDAIIKGDSELSKKYATEHIEKAEQFMID
                     KAMISKDL"
     gene            complement(7183..8073)
                     /locus_tag="PC466_002140"
     CDS             complement(7183..8073)
                     /locus_tag="PC466_002140"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HDF2769522.1"
                     /translation="MDFIRLKSRAKINLSIDVLGKRQDGYHFVEMIMQTIDLYDIVKI
                     KELDEDEIKVKSTSLDIPLDEDNIVYKAAKILKNKFYIKKGVEIFIEKNIPVAAGMAG
                     GSSNAAAVLVGLNHLWELRLSEDELKEIGLNLGADVPFCISGRPALAQGIGEKLTNIK
                     GLPCDTNILICKPDLFVSTKEVYQGLDLNNIKKRPNNKYLIECLKSEDIKAVSESMVN
                     ILENVTIGKHKEISDIKQVMMKNNALGSMMSGSGPTVFGLFKNKEDALIGKKELLKKY
                     KQVYVVNSSQKGVEICGEFN"
     gene            complement(8191..9741)
                     /locus_tag="PC466_002141"
     CDS             complement(8191..9741)
                     /locus_tag="PC466_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3794 domain-containing protein"
                     /protein_id="HDF2769523.1"
                     /translation="MELIKDVIKVDNRIDFGKFQTFIEAEAVVPDKKLDVYEIVKTEG
                     YISLKKIEMADGKILCRGSFNYNVIYIADDKNTISNVDGKVDINEVIEKDNVVQDMEY
                     MLFSEVEHMDCTIMNERKIKVGALMNIRGSLFEKQRLDIVKDVAQVEGIQKHRKEICF
                     QDIVGIEKAESSIRDTITINTEEIQSIISLNPCVKVKESRVTDNKVIIGGVLEINPLA
                     CTYEGELVELDRVGIEFTQFVEVPGVSDGMTEEVLLSMSDFNHIFKQNSESNTGLLEI
                     DCMACCKVKVTDEVTREVLQDAYSPQKIIKFDHKPIQLNKTLRRSEETFMVREGIRND
                     NDDIQIKDIVSVCPTMSIENSYIEGNKSIIQGIIKVEILFVPVEGLKLVYKISEEIPF
                     EHDIEMDNLTDTASVFNTACIDKVEVDLNRDQIDLIIKIKRFTEALDKKAENFIIKGE
                     DQGVYDLSKAPSIIVYICKEGDTFWNIAKKYNTTENEIAELNDIKLDEPIKPGKCLIL
                     EKKVVLVD"
     gene            complement(9835..10101)
                     /locus_tag="PC466_002142"
     CDS             complement(9835..10101)
                     /locus_tag="PC466_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HDF2769524.1"
                     /translation="MATVQTLDKIRVSLERHIGKKILLKANKGRKQIITKEGILEKVY
                     PSVFVIKLDDESNGYPRVSYSYSDLLTSNVKLQVFRDQDKLQIS"
     gene            complement(10249..11109)
                     /gene="yabG"
                     /locus_tag="PC466_002143"
     CDS             complement(10249..11109)
                     /gene="yabG"
                     /locus_tag="PC466_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation peptidase YabG"
                     /protein_id="HDF2769525.1"
                     /translation="MKVGDIVARKSHNKDIVFKIVSFGVDENNEKIAILKGIAFRVIA
                     DAYIDDLELVKAPDIKDILIDKNVENLLYKSVRKAKERQKRMTRAVPKLQLNPNTYGM
                     PGKVLQIDGDKEYLKICLDVYAQLGIPAVGVAVSEQNQYKEVRALLEKYNPDILVITG
                     HDAMTIKRGDIEDMSNYRNSSNFVKTVKEARKWQPNLDNLVIFAGACQSNYEKIISAG
                     ANYASSPGRIMIHALDPVFIVEKIACSRIDVVVPIDEVIEQTITGVKGIGGSETRGKF
                     RWAMPKTILH"
     gene            complement(11193..12131)
                     /locus_tag="PC466_002144"
     CDS             complement(11193..12131)
                     /locus_tag="PC466_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HDF2769526.1"
                     /translation="MKFIDLHCDTIAKLMENVETSELKSNKYSVDIDRLKKGDSLAQT
                     FALFVDTEEVKHPFDYCMSMANKFHEEMKKNSDEIALATNYEEIMKNQSEGKLTALLS
                     IEEGAVLEGKLENLKKFYDLGVRMMTISWNHVNELSFPHNKVEYREKGLTDFGREVVH
                     KMNELGMLVDVSHISDGGFYEIAKISSKPIIATHSNSRAMMNHSRNLTDDMIKVLANK
                     GGVTGINFFHLFLSDKSESKLEDMVRHIKHIVNVGGIDVVSLGSDFDGIDSKVEIEDI
                     SQMGKLYEPLKKEGFSEDDIEKIYYKNALRVIKEVL"
     gene            complement(12241..12402)
                     /locus_tag="PC466_002145"
     CDS             complement(12241..12402)
                     /locus_tag="PC466_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769527.1"
                     /translation="MFILRFADDDDNLSVKDFTSLTDLKKYISENNIDKTWHQIEEVK
                     KVIPNLKEE"
     gene            complement(12412..12909)
                     /locus_tag="PC466_002146"
     CDS             complement(12412..12909)
                     /locus_tag="PC466_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SEC-C domain-containing protein"
                     /protein_id="HDF2769528.1"
                     /translation="MSLYTEWRNLSDNHESQEAEVKFWEEYLKVEAGIYNEILNNKMD
                     VVEGKVSELAEKFGTTNEFFMGFIDGISESLKEDIVLEEVEADKEVSIKIDWEKLYNN
                     MVTVEAHWLYNLQGWEDILPADQRKEIIKAYKKSKTIVKEAKIGRNDSCPCGSGKKYK
                     KCCGK"
     gene            complement(13024..13734)
                     /locus_tag="PC466_002147"
     CDS             complement(13024..13734)
                     /locus_tag="PC466_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0489 family protein"
                     /protein_id="HDF2769529.1"
                     /translation="MENYEYSGFYIEKPVGNNVFSYDKRENKSIYVPKLINGTLNDVR
                     LGNEVVFNEVDENKEIKAKGLENMVEYVLGNKKIYVFDNHNHAFYFWAKSLLKGEFTK
                     GCKLVHVDQHKDTREPENYDVDVNNLKDVFRYTNEVLNVGSFIKPALKYNIFSELIII
                     DSLYGFDLEVESEFVLDIDLDIFSSDMDYIPFELKFYKIKNLIKKAKVITIATSPYFI
                     NQEYAIKVLKELFNYDII"
     gene            complement(13910..14440)
                     /locus_tag="PC466_002148"
     CDS             complement(13910..14440)
                     /locus_tag="PC466_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769530.1"
                     /translation="MDIRALPIRITKEEAIEIAKSGKNSLFSKLILKNKYAHEVRLHY
                     IEFKIITLKIHKTKSIFKNRRYSNDINELKILVNGSTGSGSIVQDFPTYEIVKNVDCN
                     IVQYSNKDERRVKAKANKMAMRLIHRFMGGIPEIEIVKIESIFRPYWVVFFGKVELNR
                     RVSYLPIEADGFVIGM"
     gene            complement(14457..14687)
                     /locus_tag="PC466_002149"
     CDS             complement(14457..14687)
                     /locus_tag="PC466_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769531.1"
                     /translation="MSKLVSKVKKDLEIKWLGVDGFLVLLYFLITGFIFYGILTRNDI
                     IVGKIIPYGVMAVVIVIFFDYIYRVLKMTRKK"
     gene            complement(14702..16096)
                     /locus_tag="PC466_002150"
     CDS             complement(14702..16096)
                     /locus_tag="PC466_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter family protein"
                     /protein_id="HDF2769532.1"
                     /translation="MLTFWENGIIVIFAFILLGIGYYFSRNVKDMESYYLGNRSLPWS
                     LIVGTLVASWYGGVGTVGSVEYAAIYGISAWAVWSIAAHIGRMPLALWVGPRIHIRTN
                     ITVPDLLESFYGKHVAIIGAILMFIYCAQLGEITAMGTIGNVAWKIDKELIGLIMVGV
                     VVVLTVLGGLMGVAITDMVLFFCMVFGLTMVMPGQFEQIGGFQGLTEALKDAPQLMHP
                     TKGMSAMKALMLIVYSFGAYSDPTFYQRFSAADSPKVGRRALLTCFSLWICFDMVLTI
                     TGLIVRATYPEMAPAAGYITLVLDTLPQGIRVIFIIGILGSIISTLDSYYLAAGATLA
                     NDIYGRITKKELSQKQLVKFTRIGVCLAAVMGLSVAFRFENVYDACIFVGSIWMGSAF
                     VPIVGGLLGNGRRTSMGGILGMIVGGVTFGYFKIFPVQSFELEPLVIAIPFSFIAWMI
                     GNRIGENLNTQNNL"
     gene            complement(16222..17475)
                     /locus_tag="PC466_002151"
     CDS             complement(16222..17475)
                     /locus_tag="PC466_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2769533.1"
                     /translation="MENKSNFKRFLIIFILAFGTTAMYSLPYMKSSFYDPMQQALSLS
                     HTQIGNLLSLYGLVGMVSYFIGGWFADRFSVRKLITFSLIASGVLGFYFSTFPSYSMI
                     LLIFVLWGFTTILTFFSASVKVVRMQGSESEQGRIFGFYEGLSGVSGTLISFIGLYFF
                     GKFAEITVGFKYVVWLYSAASIICGILLFFLVEEKKDSGASDEGLSIKSLLKVVTMPK
                     AWLIGLIIFSTYLVFSSLTYLSPYLSEVYVMPMTLVSALSIIRTYVIKMGASPVAGVI
                     TDKVGSSIRVMFVGFILMTVSTAAYLVIPKSTGFIWIAVINMIILSVILFGFRGIYFA
                     SVSESNISLETTGAVVGFASFIGFSPDAFYYTIAGNWLDKYGQTGYTYIFILSVVCAV
                     IGIFATYALNKINKRENKGLNNKIA"
     gene            complement(17526..18680)
                     /locus_tag="PC466_002152"
     CDS             complement(17526..18680)
                     /locus_tag="PC466_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HDF2769534.1"
                     /translation="MSNNINQDLETKIIHWGHSADPTTGALATPICQTATFAAKTVEH
                     FEELCMTWGYVYTRECNPTLTELEAKLAMLENAESAISSTSGMGAITSTILALVKSGD
                     HIVSSDGIFSHTKLFMSELLSKFGVEVTFVDAVNPQNVKEAMRPNTKIVYIESPLNPS
                     LDLVDIKTIAEIAHENKSLAIVDSTFGTPIVQRPIDLGADLVIHSLTKFINGHGDTLG
                     GAVAGSKELIDLVRWPSLCCFTGASLPPMSAWMILRGMKTLDMRMKKHCENGLAVAEF
                     LEEEENVELVKYPALKSHPQYELCKTQMNGLGGGVVSFKLKDGINGLTRDQASRKLMN
                     SLELATIATSLGEEHTLVQMNGENLIRIAVGLESSNDIINDFKQAIKKLK"
     gene            complement(19239..19808)
                     /locus_tag="PC466_002153"
     CDS             complement(19239..19808)
                     /locus_tag="PC466_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDF2769535.1"
                     /translation="MIIIYGYCRVSTKNQTDNNSLYQQQQEILNKYNDAKIIKETYTG
                     TTTNRPKFEKIISSLKKGDLLVATKLDRLARSTSEGIQLIEGLFAKEVSVHILNIGLL
                     ENTSMGKFFLTTLLAVAELERNMIIERTQLGKEFAKKKKDFKDGRPKKYSNQQIQYAL
                     GLLNSKPYREVVKMTGISKSTLIRAKKSI"
     gene            20011..20238
                     /locus_tag="PC466_002154"
     CDS             20011..20238
                     /locus_tag="PC466_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HDF2769536.1"
                     /translation="MNSLLKEAIDELKNIHCGEVFLLKELFKGYEWNRLEMNIRLKLG
                     KLFLYEVVTNPNLNVEVINKNSAYQQMYKKK"
     gene            complement(20457..21200)
                     /locus_tag="PC466_002155"
     CDS             complement(20457..21200)
                     /locus_tag="PC466_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HDF2769537.1"
                     /translation="MENYQSTNTCTYNILYVQFNEDFERSKYFSYDVKYPVIYNIRNQ
                     STYVNPVILNNINNAVRMTVNNFKNGLQEEEREYNNAASQNSLPKQSYWVSTSYAVTF
                     NKNYVLSMILNLMGFANNYGPKYNTLNNYNIDLTTGKELLLNDIFRDGVDYINIITDY
                     IKSQINENREMYYSNVELVIPEDQAFYITDNGIIIYFGVDEIAPESFGIPKFELKFSD
                     FGNFINLRFYCISPDIYVQSRGRAKHFMG"
     gene            21368..22240
                     /locus_tag="PC466_002156"
     CDS             21368..22240
                     /locus_tag="PC466_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDF2769538.1"
                     /translation="MLLLADKWKDYELIDMGNGEKLERWGSYVLRRPDPQVVWPMESE
                     WALWKNPHGHYHRSNKGGGQWEHKKRYPEQWTINYKNLKFHIKPTGFKHTGLFPEQAA
                     NWDWMIEKIKKANRPIKVLNLFAYTGGATVACASAGAEVCHVDAAKGMVNWAKENIEL
                     SGLKNQTVRFIVDDVVKFVEREIRRGKKYDAIIMDPPSYGRGPKGEVWQIEEKLYSFV
                     DLCMGVLSDNPLFFLINSYTTGFSPIVLENVLSTTIGKKTNTGDIYGGELGIPASRDG
                     KILPCGIFGRWEKK"
     gene            22240..22905
                     /locus_tag="PC466_002157"
     CDS             22240..22905
                     /locus_tag="PC466_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HDF2769539.1"
                     /translation="MIKVIYEDNHLLVVEKPVNILSQGDNTNDKDMVNLLKDYIKKKY
                     NKPGNVYIGLIHRLDRPVGGVMVFAKTSKAASRLSEQVRSKTFKKTYLAVVHGKIKSN
                     SDILKDFLYKNKKTNMVTVVKKSHKDAKEAELNYNVLDFKENLSLVQVNLKTGRSHQI
                     RVQFASRKHPLYGDQRYGKEINKIGQQISLWSNKIEICHPTTKEKMEFTCHPPDKYPW
                     NIF"
     gene            22926..23783
                     /locus_tag="PC466_002158"
     CDS             22926..23783
                     /locus_tag="PC466_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF2769540.1"
                     /translation="MSKKFSIGEMSKLHKISIQTLRYYDQIDLFKPVHVDQESNYRYY
                     SIDQFSQLDIIKYLKYLGMPLKEIKSKLDENNEEILKLLTNKINIVDEKIKELELIKK
                     VLSTKKETMEKGMKVDEVGKIVRKHIPRRSILSIEYEEGLSSEETMELSRRQIANILE
                     DNISVFYGGVSGLVSIDKFLKEDKVIYDNSFVTVERDLFDIKSQKHITEISSGDFICM
                     TYKGSYKENYTAFKKLVDYVEYKRIPIENYIYEIPIIDPLSTNNEEELLTEIQIQVKK
                     REIDLRCLV"
     gene            complement(23939..26485)
                     /locus_tag="PC466_002159"
     CDS             complement(23939..26485)
                     /locus_tag="PC466_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HDF2769541.1"
                     /translation="MNIFNKVALQGLKKNRTRTLVTIIGVVLSAAMITAVTTFGVSLM
                     NYMTNGAIIKYGDWHVQFLDVDSSFVQEQRVNDEVANTATFENIGYATLEGNRNPDKP
                     YLFIAGFSKEAFDTLPITLISGRLPENSREILVSSKVATDGGVKFAVGDTISLDVGKR
                     MSENEKLGQSDPYTAGSEVFVPQDKKTYTVVGICRKPVFEESSAPGYTLITKEDKQVK
                     TDSLSLFVTLKNPHQIRSYTSSTKDHASIFNDNVLRFIGVSDNNLFNMFLYSVGGIVL
                     AIIMLGSIFLIYNSFNMSLNERTHQFGILSSVGATAKQLRNSVLFEGICIGAIGIPIG
                     VAIGIVSIGLVISVIAKNFANILYVNVPLTLTLSIPAIIVAAVVSMVTILISAYIPAR
                     KAANTPVMECIRQTNEVKIESKSVKTSKLTQRVYGLEGVLAMKNFKRNKKRYRSIVLS
                     LVLSIVLFISTSALVADLKQMSNQRSEVTDQDIIFSTQGMKDNEMLKLYDKLKTANGV
                     YEGLYQKLMTYSCVAKVSELTDDYLNYEGSHSMSEMLELPVDMQFLDDRTYLNIIKSL
                     GLPAEEYTGQNAKLIAVSMVTKDNNIIDIFNSSSMNVSLTPETNGKLEIPERQNVNIS
                     FVKVVPPDSPPGIRSSDVKKASFRVLAPYSAKDKFEIPGVSTGIESLSFQSKNPTQSV
                     AEMEQIIESEGVTNEYNLYNMYGMMDENRNYIFIANVFAYTFIIMISLISIANVFNTI
                     STNIKLRRRELAMLRSVGMSEHDFQKMMNFECAFYGMRALFFGLPIAVISSWLIHKVM
                     VTDDIDFVIPWFSIGISIFSVLFIVFITMLYTINKIKKENIIDALRDDMA"
     gene            complement(26485..27171)
                     /locus_tag="PC466_002160"
     CDS             complement(26485..27171)
                     /locus_tag="PC466_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2769542.1"
                     /translation="MAFLKIEDLCKVYGKNENKVTALDHVSLTIEKGEFTAIIGSSGS
                     GKSTLLHSIAGVDVPTSGKIYLEGQDVYGQSNEKLAIFRRRQVGLIYQFHNLIPTLNV
                     VENITLPILMDKRKVNQERLNDLLELLGLKERKTHLPNQLSGGQQQRVAIGRALMNAP
                     AVMLADEPTGSLDSKNGQEIIQLLKESHSKYHQTLIIVTHDENIALQADRIICISDGK
                     VVRDERKVNR"
     gene            complement(27254..28243)
                     /locus_tag="PC466_002161"
     CDS             complement(27254..28243)
                     /locus_tag="PC466_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2769543.1"
                     /translation="MFRNREFRKFAILFLLITILTVALGFAISIMTGILSIVSATTFG
                     IAFFVFTKNRYKSIAQISEQINLVLHNANHLYIAESDEGELSILQSEITKMTLRIREQ
                     NYALKKEKEHLADSLADIAHQLRTPLTSVTLILSLLENTSDEDERKELIRETEELLIR
                     MDWLITSLLKLSRLDAGIVVFQKEQIDVNNLISSALHQLLIPMELHNITLHIDIPKGV
                     RILGDLNWLSEAIQNIFKNCMESVGDNGKIDIVCEDNFLFTQLTIHDNGAGFKKEDLP
                     CLFNRFYRGKNSSTAGYGIGLALCKTIIMRQGGTITAQNHPQGGAIFVIRFPK"
     gene            complement(28230..28916)
                     /locus_tag="PC466_002162"
     CDS             complement(28230..28916)
                     /locus_tag="PC466_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2769544.1"
                     /translation="MKRIFLVEDDKAIAKNLILLLNSEGFIVTHVSTRSEALVEIAKN
                     KFDLALIDISLPDGNGFTICTEIKEKQDIPVIFLTASGDESSVVTGLNMGADDYITKP
                     FRPRELIARIRTALRKSGRFGSTFEICGLYVDTATGVVKKNGNEVFLSALEYRLLLVF
                     ISNPKSIITRVRLLDELWDAAGEFVNDNTLTVYIKRLREKIEDDPSSPQIILTVRGTG
                     YRLGGSYVSK"
     gene            complement(29416..>29654)
                     /locus_tag="PC466_002163"
     CDS             complement(29416..>29654)
                     /locus_tag="PC466_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769545.1"
                     /translation="IEEPRPNILDAIRNKQVDIVINTPTKGNDSTRDGFKMRRTAIEF
                     STEIMTSLDTLKALVEVKKKHLNKDKLKVYNIAE"
BASE COUNT         9655 a         5370 c         3411 g        11218 t
ORIGIN      
        1 tttaaataat tttaaaataa taaaaaactg aaagtatcaa ttaaattaat acatgcaaat
       61 ataatttgct tattaattta atattatact ttcagtttta gtatttaatc cacatcagat
      121 aataatctta aaatgaccaa ggtcttaaaa ctatttatct ttatcagatt tatcttctaa
      181 atttttattt atatcaataa cattgtttct ttcttcttca tctttttcta attttatagt
      241 taattgttct tcaacttctt tagaagaatt ttcctctgta actgcatttt caatttcatt
      301 cagaggtaac tctttattaa atgcttttac aaattgttct gcatctaaag tttcatatat
      361 aagtaaagct tgtgctacat actctaatct atccatattt tcttgtaata tacttcttgt
      421 cttatcatat gcaccatcaa ctatacgctt tgtttcttgg tctatctcaa aagcaacttc
      481 ttcagagtaa tttctcttac ttgaaaaact attacctagg aatacttcat catcactgtc
      541 aaatgacatt ggaccaagtt tagaactcat tccatacttt gttaccatac ttcttgcagt
      601 agctgtaact ctttctaagt catttgaagc acctgtagat acatccttaa gtactagctc
      661 ttctgctact ctaccaccaa gtaaaactac aatattttct ttcatttcat tttttgtagc
      721 atagaactta tcttcaacag gaagttgcat tgtaaaccct ccagctcttc ctcttggaac
      781 tattgtaact tgatgaacag gacttacttc ttcaagtaca tgggcacaaa ctgcatgccc
      841 tccttcatgg tatgctgtaa gtcttctttc tttctcactt attactttcg attttttagc
      901 cacacctgct ataacctttg ttatagcttc ttctatagtt tccatcttaa ttttcttttc
      961 tctttttcta gctgttaata ttgcagcctc attcattaag ttctctatat cagcaggagt
     1021 aaatcctggt gttcttctag ccaagacatc catttttaca tcatcactta atggtttatt
     1081 tcttgagtga actttaaata tagcctctct accttttaca tctggtgtac caacaacaac
     1141 ttgtctgtca aatcttcctg gtctaagtaa agctgggtca agtatatctg gtctatttgt
     1201 agctgccatg attattatac cttgatttac cccaaatcca tccatttcaa ctagaagttg
     1261 attaagagtt tgctctcttt catcatgacc tccaccaaga cctgcacctc tttttctacc
     1321 aactgcatca atttcatcta tgaatatgat agctggagca cttttcttag cctgttcaaa
     1381 taaatctctt actcttgaag caccaacccc aacaaacatc tcaacgaaat cagaaccact
     1441 tatactgaaa aagggaactc ctgcttctcc tgcaactgct cttgatagat atgttttacc
     1501 agttccagga ggtcctacca taagcattcc ttttggtatt cttgcaccca attcaatata
     1561 tttcttagga ttctttaaga aatctactac ctcctgcaaa tcttcttttt cctcatctag
     1621 tccagctaca tctttaaatg taactctagt tttttcatca tctttatgaa ccttagcttt
     1681 tgatttgcca aaactcataa cctttccgcc tccaccttga gactgattca taaacacgaa
     1741 ccaaataatc accatgaaga atattaacag taatgtaggc aacatttcga caaaccaagg
     1801 tgtagatggc ttagcttcac caccaaaagt tagtttccca gccttagctt ggtctaacac
     1861 ctcatctgca agtttatttc ccatcacttc tgttggaaca tatgacttaa actttgtatt
     1921 tgtatctttt atagtacctt ctacagaagt ttgatttaca aagtataatc ttgatatatt
     1981 ctcatctgtt aattctctat atacttcaga gaattttaaa tcttttattt tttctgtagg
     2041 cttacctgag aattgaacta tacctactat aattataaaa acaagtagat aaaaacctgc
     2101 cccttttagc aacttattca atatagaagc cctcctttca tacattgctt tgccctataa
     2161 tttgttaaaa ttaattttta atacttcttt tgtgttttca tcaattttat aattttcact
     2221 gattttataa tctccaacac atattattcc ttcactatct gtgattatag gaattttaca
     2281 tctttcttct cttgggattt ttaaatctat gaataaatct ttcacttttt tacttcccat
     2341 agcaagcttt atcttatcac cttgccttct gcttcttatt actatacccc cttttacctt
     2401 attaaaatca aaccctttag atgaattgtc taatttcata ctcttatacc tatctatgct
     2461 cattacttgg gtctcaataa tttgttttaa ttcttttatt ttaataaacc cattactagg
     2521 tacattgtaa taaaattcaa tttcctcatt aacaatttcc tcattcgtta atattatact
     2581 gtcttttttt ctataaacaa atatatttct tggaagagtt aacattttat ttacttttga
     2641 attatcttct aaagacatta tatcttctat atgtctttgg tcaacaaaat tagtatctcc
     2701 tagtatatgt tttatggaat ttctaagaac tctaactttg atagcatcat gtaagcaaac
     2761 aaaatcgtct aaatttatct ctacaaagcc tttttctttt atatttgaaa cttctctaaa
     2821 tttagcttct gcctctttct caatataatc gttatcactt tttaaactat tgctcatcct
     2881 cactatagat tctattacat ttgaattaaa attatccttc atatatggta aaaggtctaa
     2941 ccttatctta tttctagtgt atatattttc taaatttgtt ttatctatcc tcggatttaa
     3001 attataagct tcacaatact cctctatctc atttctttcc acgtctaata tgggtctaat
     3061 tatgcaatta tctctaatat aatcaattcc ctttaagcct tttaagcctg ttcctctcat
     3121 gatacgcatc ataacagttt cggcttggtc attgagatta tgacctattg ctattttatt
     3181 ggctttaatc ttatccttaa tttcataaaa catttcatat cttagcttcc ttgctccttc
     3241 ttctaatgat aatccctcat tttcacaata ttttggtaca ttaatagact ttacaaagaa
     3301 tataattccc atatcctcac aaagtttaga tacatataat gcatcttttt gagcttctat
     3361 ccctcttatt tgatggttta aatgtgctgc atatatttct atattaaaat ctttttttaa
     3421 tctatttagt acatgcaata aacaaactga atcaggtcct ccagaaagac ctaaaactat
     3481 tttatcgcct ttttgtatta aattatgttt atttatagta cttagtacct tatcaaatat
     3541 catatttatc cctcttacac ttagttttat tcacttttaa gtatactttc tataaaaaaa
     3601 cgctaaaccc ttgtatcaat tttaagaaat taaagtttaa tataaatata ataataccaa
     3661 ataaattaaa taaaaggtag ttttttcact acctttataa aatttctgga aaatagccat
     3721 agttattatt tagtacctat gtatatatct attttattcc tacctaaaaa taaatcttgt
     3781 acctttatat tatagtctat tttcaatttt atgtgttccc cttcttgtat atttatatct
     3841 aattctcttg tatcaatatc aattaataaa gtaccttgtg gggtcacata ctttgtagta
     3901 ctactttctc cacatttaaa cagcattgtt gagttaatag caccaaactt tttgatacta
     3961 acttgatttt taagtatctt tatagtatta gttatttcta tattttcttc tttttccttg
     4021 taaataacat atattccatc atttttataa aaaattttac caaaggcagt catctctatg
     4081 gtgtccatat ttcctttttc atcatattgt ctagtattta tacttatttt tacactcaac
     4141 gatttttcct ccatagattc ttcatataaa ctagtatttt tgtatttcta ctttttgaat
     4201 cttatcaatt tttttcttta agaactctct tgctatatct gaaaattttt caggtatatc
     4261 tgatacataa tattgataag tcccatgaat ttctgtattg tttataatat tttgcacctc
     4321 taaaatcttt tttaaatcct ttgcagtctc tttagctgga ttaacaagtt ttatatgctc
     4381 tccaacttct tcacctattg ttctctttaa aataggataa tgagtacatc ctaacactaa
     4441 agaatctata tttttttctt tcaattcttg taaatatatc tttgctgtca atttagccac
     4501 ttctgtattt gcccatcctt cttcaacaat aggtacaaat aaaggacatg ctttattaac
     4561 aatttctata ctctcatcta ttttagatat ttccaagttg tatgcttttg aacttatagt
     4621 tccttcagtt cctattattc ctacaatttt gttttttgta gaacttacag ctgttctagc
     4681 tcctgcttct ataactccaa ttatcggtat atcatatttt tcttgagctt cttttaagct
     4741 tcttgcagta gcagtgttac atgctataac tatagctttt acaccttttg tttttaaaaa
     4801 gtttatagct tgaaaagtat atttaattat agtttctttg gatcttgaac catatggtat
     4861 tctggcagta tctccaaagt atattatatc ctcatttggt aatatcttca ttatctcttt
     4921 tagaactgtt aatccaccta atcccgaatc aaaaactcct attggtttat tgttcatctt
     4981 tatacaacac ctactttaca tttttgtgtt taacaacaac ttatttatcg ctaaaattta
     5041 tatttatatt cataattaat atattattac ctaaatgatt attatagttt attttacaca
     5101 aaaaataaag gagctatctt aaattagaaa ataatttcta caaaaagaca actcctttca
     5161 ctacttaaaa atttaaattt attttgcaaa cacatgattt cctattctca tataaggatt
     5221 caatctattt atccatttgc aagtggctat ttctggattc caaaaatata ctgctttatt
     5281 agttgggtca gttccataaa gagcttcctg agctgcttta cgtgctgagt ctgttggtgc
     5341 catctttatt gaaccatcaa gcacaactga gaaagcattt ttttgatata tgacttcttc
     5401 tattgtgtct ggaaatctag ggtccaatac tctatttatt actacagctg ctacagcaac
     5461 ctgtccctca tagctttctc ctctagcttc tcctgcaacc aacttagata ataacatcaa
     5521 gtcattatca gataaattta ttacttcttt ctttgctata tttttttctt gtttgtttac
     5581 tttcttaata ttttctgttg gttcatatgc aaatacctct ttaataggca taaatataaa
     5641 agtcaaagct aatagtgtag ccatcagttt actccacctg tccatgatta aaaccactcc
     5701 ttacattctt atttttaaaa ttttttctct aaatccttga ctacttcaag tactttaaac
     5761 ttaattttta ctctacttgt tttttttggt gtatcttgtt ttattaactt atattcttta
     5821 tcagttaaaa cttccttcaa cttatcatct gtagatttat ctatcactcc attagattca
     5881 tcaacaaaac atagtggagg gaacataaca caccaccagt tttttccttc acctttccca
     5941 atgataatct ttaatgcttt atattcacca gctggaagaa ctatattaga atattgttta
     6001 gtagggaaat tgctatattg tatacctacc tttacactgt aattatatcc atttttaaga
     6061 ataatatttt tacttatttc ttccagacta ctatattcct tttttataat agcttcactt
     6121 tcttttatac tttttgaatt ttgaagcttt ggctgtaaat attttattac ttcatctcta
     6181 acttttagtt taagttcttg atcttcatct gtattgctgt ttgctataac atgaaatctt
     6241 attaatttat ctttataatc ttttgatata ttgtctactt tttttacctc accatttatt
     6301 actattgtca ttattgatat gactgatata agacttaata ttaatagtcc caatctaatc
     6361 ttaatttttc tcattgaaaa ttccccctca agataaattt atatcatcaa ttatgtccaa
     6421 ttaaatttaa tttattcata atatttttta atactaataa aaaaagctat cttaaaatga
     6481 ttacaatcat tttaaaatag ctttttaaac cttatatttt ataagtcttt actaatcata
     6541 gccttatcta tcataaactg ctctgctttt tctatatgct ctgtagcata cttcttggat
     6601 agctcactat cacctttaat tatagcatca agtaagtatt tatgctcttc aacaatatta
     6661 tgtgatgtat cataagcaga catataggta actctaaatc tatatacttg ttcccataat
     6721 gagtttatta gttggattaa ttttttatta ttagttgctt taaatataca ttcatgaaat
     6781 tctacatcaa gttttaataa cgcatctaca tcggattcca aagtgctttt tttaaattct
     6841 tctgatatat ctttaagctt tttaatatct tcatcactaa ttctttcagc ggcaagatat
     6901 gctgctaagc cttctaggct tgctcttact tctaatacat ccataatatc ctttaatgac
     6961 atatttgcca catacgcacc ttttctaggc aacataacga ctaaaccttc taattcaagc
     7021 tttcttattg cctctctcac tggagtccta cttactccta attgttctgc tagttgcact
     7081 tccattagcc tttgaccagg ctttaatttt ccttctaaga ttgcttctct taaattctca
     7141 aagactacat ctcttaatgg cttgtaatta tccaagttca gtttagttaa attctccaca
     7201 aatttcaacc cctttttgac tgctattaac aacatacacc tgtttatatt tttttaataa
     7261 ttcttttttt ccaattagag catcttcttt atttttaaat agtccaaaaa ctgtaggacc
     7321 acttccactc atcatagaac ctaaagcatt atttttcatc attacttgtt ttatatcact
     7381 tatttctttg tgtttaccta tagtaacatt ttcaagaata tttaccatgc tttctgatac
     7441 agcttttata tcttcagatt ttaaacactc tatcaaatat ttattatttg gtcttttttt
     7501 aatattattc aaatctaatc cttgataaac ttctttagta gaaacgaata agtctggttt
     7561 gcatatcaat atatttgtat cacatggtaa acctttgatg tttgttagct tttctccaat
     7621 accttgagct aaggcaggtc ttcctgatat acaaaaagga acatctgcgc ccaaattaag
     7681 tcctatttct tttaattcat cttcagataa tctaagttcc cataggtgat ttaaacctac
     7741 taatactgcg gctgcattag aacttcctcc agccatccct gctgctacag gaatattttt
     7801 ttctatgaat atttctacac ctttttttat ataaaattta tttttaagta ttttggcagc
     7861 tttataaaca atattatctt catctaaagg aatatctaaa ctagtgcttt ttacctttat
     7921 ttcatcttcg tctaattctt ttatctttac tatatcgtat aaatctatcg tttgcattat
     7981 catttcaaca aaatgataac cgtcttgcct ttttcccaag acatcaatgg ataaatttat
     8041 ttttgctcta ctctttagtc ttataaaatc cattctatcc tccttgttta aagaataatg
     8101 catcactaac aataatatta tactacaaaa aataaaataa tagggtatta taatacccta
     8161 ttatacttaa ttactttaaa ttttttaata ttaatctact aatacgactt ttttttctaa
     8221 aataagacac ttaccaggct taattggttc atcaagtttt atatcattaa gttctgcaat
     8281 ttcattttct gttgtattgt atttttttgc tatattccag aaagtatctc cttctttgca
     8341 tatatatacg attatgctag gagctttaga taaatcatat acaccttggt cttctccttt
     8401 gataataaaa ttttctgctt tcttatctaa tgcttcagta aatctcttaa ttttgataat
     8461 caagtctatc tggtccctat tcaaatcaac ttcgacttta tcaatacatg ctgtattaaa
     8521 cacagatgct gtatcagtta gattatccat ttctatatca tgttcaaatg gaatttcctc
     8581 actaatttta taaaccaatt ttaaaccttc aactgggaca aataaaattt caacttttat
     8641 gattccttgt ataatgcttt tatttccttc aatataacta ttttctatag acatggttgg
     8701 acaaacgctt acaatatctt ttatttgtat atcatcatta tcatttctta tgccttctct
     8761 aaccataaat gtttcttcac tacgtcttaa agtcttattt aattgaatag gtttgtggtc
     8821 aaattttatt atcttttgag gcgaatatgc atcttgtaat acttctcttg taacttcatc
     8881 tgtaactttt accttacaac aagccataca atctatttct aaaagacctg tgttgctttc
     8941 actattttgc ttgaaaatat gattaaaatc tgacatagac aacaatactt cttcagtcat
     9001 accatcacta actccaggga cttctacaaa ttgagtaaac tcaataccta ctctatccaa
     9061 ctctacaagt tcaccctcat atgtacaagc taacggattt atttctaata ctccaccaat
     9121 aataacttta ttgtcagtca ctctactttc ttttacttta acacatggat ttaaacttat
     9181 tatagattga atttcctctg tgtttattgt tatagtatct cttatagaac tttctgcttt
     9241 ttctattcca actatatctt gaaaacaaat ttcctttctg tgcttttgta tgccttccac
     9301 ttgcgccaca tcttttacaa tgtctaacct ttgcttttca aacaaacttc cccttatatt
     9361 cataagagct cctactttaa tctttctctc attcattata gtacaatcca tatgctctac
     9421 ttctgaaaat aacatgtatt ccatatcttg aacaacattg tctttttcta ttacttcgtt
     9481 tatatctact tttccgtcta cattagaaat agtattttta tcatctgcaa tatagattac
     9541 attataatta aaactacctc tgcaaagtat cttcccatct gccatttcaa tttttttaag
     9601 tgatatgtat ccttctgttt ttacaatttc atatacatct aattttttgt ctggtacaac
     9661 tgcctccgct tcaatgaatg tttgaaattt tccaaagtct attctattgt caactttaat
     9721 tacatcttta attaattcca tagtctacct ccttaagtat tataaaaata tcacactata
     9781 tttatattta aggagcaaaa aaaaaattac acctattttt aaataggtat aattttaact
     9841 tatttgtaat ttatcttgat ctctaaaaac ttgcaacttt acattagatg ttaataaatc
     9901 tgagtaacta taagatactc taggatatcc attactttca tcatctaact ttataacaaa
     9961 cacgcttgga taaacttttt ctagtatacc ctcttttgta ataatctgct ttcttccttt
    10021 attagctttc aacaatattt tctttcctat atgtctctct aagcttactc ttatcttatc
    10081 tagagtttga acagtagcca caatatcacc ttctttaacg tttatatgtt tacataatat
    10141 cacatataaa catttttgtc aaatgtttaa actaattatt ttatatattt tttgcaaaaa
    10201 tgtcaatact atttttgaag atatacagta taattatgtt aatttttgct aatgtaatat
    10261 tgtttttggc attgcccatc taaattttcc tcttgtttca gaaccaccaa ttcccttaac
    10321 acctgtaata gtctgctcta taacctcatc aataggaact actacatcaa ttcttgaaca
    10381 agcaattttc tccactataa aaacagggtc taatgcatgt atcattattc ttccaggcga
    10441 acttgcataa tttgctcctg cacttattat tttttcataa tttgattggc atgctcctgc
    10501 gaatatgaca agattatcca aatttggttg ccatttacgt gcttctttta ctgttttaac
    10561 aaaatttgaa gagtttctat agttactcat atcttctata tctcctcttt ttattgtcat
    10621 tgcatcatga cctgttatta ctagtatatc cggattatat ttttctagta gtgctcttac
    10681 ttctttatac tgattttgct ctgaaacagc tacacctact gcaggtattc caagttgagc
    10741 atatacatcc aagcaaattt ttaaatattc tttatctcca tctatctgta gtacttttcc
    10801 aggcattcca tatgtgttag gatttaattg aagttttgga actgctctag tcattctttt
    10861 ttgtctttct ttagcttttc ttactgactt atataataaa ttttctacat ttttatctat
    10921 taatatatct tttatatcag gtgcttttac taattctagg tcatcaatat aagcatctgc
    10981 tattactcta aatgcaattc cctttagtat agctattttc tcattatttt catctacacc
    11041 aaaagagact attttaaata ctatatcttt gttatgtgac tttctagcta caatgtctcc
    11101 taccttcata gttaaacctc caataaattt ttatcttagt ttatactatg ttcgatataa
    11161 aactttgttt cctaatgtca aaaaaacatt tcttataata cttcttttat cactcttaaa
    11221 gcatttttat agtatatctt ttctatatca tcttcactaa acccttcttt ttttagaggt
    11281 tcatacagtt tacccatctg agatatatct tcaatctcaa cttttgaatc tattccatca
    11341 aaatctgacc ctagggatac aacatctatt cctccaacat ttacaatatg ttttatgtgt
    11401 ctaaccatat cttcaagttt actttcactt ttatcactta aaaataagtg gaagaagttt
    11461 atacctgtaa ctccaccttt atttgctaat actttaatca tatcatcagt taaatttcta
    11521 gaatgattca tcattgctct tgaattagaa tgtgtagcaa ttattggttt agaagaaatc
    11581 tttgcaattt cataaaatcc accatctgaa atatgagaaa catcaaccaa cattcccaat
    11641 tcattcatct tatgtaccac ttctcttcca aaatcagtaa gccctttttc tctatattct
    11701 actttattat gaggaaagct caattcattc acatgattcc aacttattgt catcattcta
    11761 acccctaagt cgtaaaattt ctttaaattt tctaatttac cttcaagtac tgcaccttct
    11821 tcaatagata aaagagctgt aagtttacct tctgattggt ttttcataat ttcttcatag
    11881 ttagtagcta aagctatttc atcactattt tttttcattt cctcatgaaa tttatttgcc
    11941 atactcatgc aataatcaaa aggatgtttt acttcttcag tatcaacaaa aagagcaaat
    12001 gtttgagcta atgaatcccc ctttttcaat ctgtctatat caacagaata tttattagac
    12061 ttaagttcac ttgtttctac attttccatt aattttgcta tagtatcaca atgtaaatca
    12121 ataaatttca tatttatacc ccctgtatat tttatattta tatctaaaaa tagaaatagt
    12181 tgtccttata gacaactatt gacaactatt ttttaatatt ctttttaata ttacttaatc
    12241 ttattcttct tttaagttag gtattacttt tttaacttct tcaatttgat gccatgtttt
    12301 atctatatta ttttcactaa tatatttttt taaatcagtt aaagatgtaa aatctttaac
    12361 tgataaattg tcatcatcat ctgcaaatct taaaataaac atgagactcc cttactttcc
    12421 acaacatttc ttatattttt ttccgcttcc acatgggcat gaatcatttc ttcctatttt
    12481 tgcttcttta actattgttt tagacttctt ataagccttt attatttctt ttctttggtc
    12541 tgctggtagt atatcttccc aaccttgtaa attatatagc caatgagcct caacagttac
    12601 catattgtta tataattttt cccaatctat ttttatagaa acttctttat cagcttctac
    12661 ttcttctaaa actatatctt cttttaagct ttcacttatt ccatctatga atcccatgaa
    12721 aaattcatta gtagttccaa atttttcagc caattcactt actttacctt caacaacatc
    12781 cattttatta tttaatattt cattgtatat tccagcttca actttcaaat attcttccca
    12841 gaattttact tctgcttctt gactttcatg attatcactt aaatttctcc attcagtata
    12901 taaactcata ctttttcctc ctaagtatac ctatattttt atagttttta tagtataaaa
    12961 tcttttagtt agattggaag tttcttcttt ttgattatac catattctat ttaaagttaa
    13021 ctcttatatt atatcataat taaacaattc ttttaatact tttatagcat actcttggtt
    13081 tataaaataa gggcttgtcg caattgttat tactttggct tttttaatta agttttttat
    13141 cttgtaaaat ttgagttcaa atggtatata gtccatatca cttgaaaata tatccaaatc
    13201 tatatcaaga acaaactctg attctacttc taaatcaaat ccatacagac tatctattat
    13261 tattaattct gaaaatatgt tatattttaa agcaggtttt ataaaacttc ccacatttaa
    13321 aacttcattt gtatacctaa atacatcttt tagattattt acatctacat catagttctc
    13381 aggctctcta gtatccttat gttggtctac atgcactaac ttgcatcctt ttgtaaattc
    13441 accctttaac aaagattttg cccaaaaata aaatgcatgg ttatgattgt caaacacata
    13501 tatcttttta tttcccagga catattcgac catattctcc aatccttttg cttttatttc
    13561 cttattttca tctacttcat taaataccac ctcattgcct aaccttacat catttaatgt
    13621 accatttata agttttggaa cgtatatgct cttattttct cttttatcat atgaaaatac
    13681 attatttcct actggttttt ctatataaaa tccactatat tcataatttt ccataaaact
    13741 ttatttcctc cattgttata taaatatata agttataatt ttaaaaatta aaatgcactt
    13801 attgtaaatc atattatcta ttatagaaaa catcttatat aactaaatat aatatcttct
    13861 ctcaatatgt attatacaat aagtgcaaaa tatatttata taaaatatac tacattccta
    13921 taacaaaacc atcagcttca attggaaggt aactaactct tctattcaac tccacctttc
    13981 caaaaaatac tacccaatat ggtctaaaaa tactttcaat tttaactatt tcaatctctg
    14041 ggattcctcc cataaaccta tgaattaatc tcatagccat tttatttgcc tttgctttta
    14101 ctcttcgttc gtccttatta ctatactgca caatattaca atccacattt tttacaattt
    14161 catatgtagg aaaatcttgt actatactac cagaacctgt agaaccattc actaaaattt
    14221 ttaattcatt tatatcatta gaatatctcc tattcttgaa aatggatttc gttttgtgaa
    14281 ttttaagtgt gataatttta aactctatat aatgaagtct aacttcatga gcatatttgt
    14341 tctttaatat tagcttacta aataaagaat ttttcccact tttagctatc tctatagctt
    14401 cttcttttgt aattcttata ggtaacgctc ttatatccat aaaatcattc tctttcttat
    14461 ttttttcttg tcatttttaa aactctatat atataatcaa aaaatattac aattacaact
    14521 gccataactc catatggaat tatttttcca actataatat catttctagt caatatacca
    14581 taaaatataa atcctgttat taaaaagtac aataatacta gaaaaccgtc tactccaagc
    14641 cattttattt ctaaatcttt ttttacctta gacactaatt tagacatagc agtttctcct
    14701 tttatagatt attttgtgta tttaaatttt cacctattct attaccaatc atccatgcaa
    14761 taaatgaaaa aggtatagct atcacaagag gctctaactc aaagctctga actggaaata
    14821 ttttaaaata accaaaagtc actccaccta caatcattcc taaaatacca cccatagatg
    14881 ttcttcttcc atttccaaga agcccaccta ctataggtac aaatgccgaa cccatccaaa
    14941 tacttcctac aaatatacat gcatcatata cattttcaaa tctaaatgct acgctaagcc
    15001 ccataactgc tgctaaacat acacctattc tagtaaactt tactaattgt ttctgagata
    15061 actctttttt tgtaattctt ccatatatat catttgctaa tgtagctcca gctgctagat
    15121 aatagctatc caatgttgat attatagaac ctaaaattcc tattataaat attactctta
    15181 ttccttgtgg taatgtatct aaaactaaag ttatatatcc agcggctgga gccatctctg
    15241 gataagtagc tcttactata agtcctgtta tagttaacac catgtcaaaa catatccata
    15301 gtgaaaaaca agttaataag gctcttcttc caaccttagg agaatctgct gctgaaaatc
    15361 tttgataaaa agttgggtct gaataagctc caaaagaata tacaattaac atcaatgctt
    15421 tcatagctga catacctttt gtagggtgca taagctgtgg tgcatctttg agtgcttctg
    15481 tgagaccttg aaatcctcct atttgttcaa attgacctgg cataaccata gttaaaccaa
    15541 ataccataca aaaaaacaat accatatctg taatggcaac tcccataagc ccaccaagta
    15601 ctgtaagtac aacgactact cctaccatta ttaatcctat taattcttta tctattttcc
    15661 atgctacgtt acctatagtt cccatagcag ttatttctcc aagttgtgca caatatataa
    15721 acatcaaaat tgccccaatt atagcaacat gcttaccata aaaactttcc agtaaatcag
    15781 gaactgttat attggttctt atatgaatcc ttggaccaac ccacaatgct aaaggcattc
    15841 tcccaatatg tgcagctatt gaccaaactg cccatgcaga tattccatat atagccgcat
    15901 actctacact acctactgta ccaactcctc cataccatga tgcaaccaaa gttcctacta
    15961 ttaaggacca tggtaaactt cgatttccta ggtaataact ttccatatct tttacatttc
    16021 tagaaaaata ataacctatt cctaataata taaatgcaaa tataactata atcccatttt
    16081 cccaaaatgt taacatatct aatctccaca ttcttatatt ttaattttta actttaatat
    16141 ctaaatatga acaactctac ccatttccat aaaaataggt agagttatat aataattata
    16201 agtatttaag taatcttgtt attaagcaat tttattgttt aaacctttat tttctctttt
    16261 atttatttta tttaaagcat aagtagcaaa tatccctata actgcacata ctacagataa
    16321 aataaatata tatgtatatc ctgtttgtcc atatttatct aaccaattac ctgcaatagt
    16381 gtaataaaac gcatctggag aaaatcctat aaatgaagca aatccaacta ctgctcctgt
    16441 agtttctaaa gatatattag actctgaaac agatgcaaag tatatacctc taaatccaaa
    16501 taaaattaca cttagtatta tcatgtttat tacagctatc catataaatc ctgtactctt
    16561 aggaataacc aagtaagcag ctgtacttac tgtcattaat ataaatccta caaacattac
    16621 tcttatagat gaaccaactt tatctgttat aacaccagca actggagatg ctcccatttt
    16681 tataacataa gttcttatta ttgataaagc agaaactaga gtcattggca ttacataaac
    16741 ttctgataag tatggactta aataagttaa acttgagaat actaaataag ttgaaaatat
    16801 tataagacca attaaccaag cctttggcat tgtaactact tttaacaatg acttaatact
    16861 taatccttca tctgatgctc cactatcttt tttctcttcc actaagaaaa atagaagtat
    16921 accacatatt atagatgctg cagaatataa ccatactaca tatttgaatc ctactgttat
    16981 ttcagcaaat ttaccaaaga agtaaagacc tataaaagaa attaacgtac ctgatacacc
    17041 tgataaccct tcataaaaac caaatattct tccttgttct gactcacttc cttgcattct
    17101 aacaacctta acagatgctg agaagaaagt taatattgtt gtaaatcccc ataatacaaa
    17161 tattaagagt atcatactat atgatgggaa tgtagagaaa taaaaaccaa gtactcctga
    17221 agcaattaaa gaaaaagtta tcagctttct aaccgagaat ctatctgcaa accatcctcc
    17281 tataaaataa gataccattc ctactaatcc atataaactc aataagttcc ctatttgtgt
    17341 atggctcaat gataaagctt gttgcattgg gtcataaaat gatgatttca tatatggtaa
    17401 actatacata gccgttgttc caaatgccaa tatgaatatt atcaagaatc ttttaaaatt
    17461 acttttgttc tccattaatt ttctctcctt aaaattttat tgtttataat ctcattcatg
    17521 taattttatt ttaatttttt tattgcttgt ttaaagtcat ttattatatc atttgaagat
    17581 tctaatccta cagctattct tattagattt tctccattca tttgaactaa tgtatgctct
    17641 tcccctaagc ttgttgctat tgttgcaagc tctaaagagt tcattaattt tctactagct
    17701 tggtctcttg tcaatccatt gataccatcc ttaagtttaa atgaaactac acctccacct
    17761 aaaccattca tttgagtttt acaaagctca tattgaggat gagattttaa tgctggatac
    17821 tttaccaatt ccacattctc ttcttcctct aaaaactctg ctactgctaa tccattttca
    17881 caatgctttt tcatcctcat atctaacgtt ttcatacctc ttaaaatcat ccatgcactc
    17941 attggtggta aagatgctcc tgtaaaacaa cataaacttg gccatctaac taaatctatt
    18001 aattcttttg aacctgctac tgctccccct aaagtatccc catgtccatt tataaactta
    18061 gtaagactat gtattactaa atctgcacct aaatctattg gtctttgtac aattggtgtc
    18121 ccaaaagtac tatcaactat agctaagctt ttattttcat gagcaatttc tgctattgtt
    18181 tttatatcta ctaagtctaa tgatggattt aaaggacttt ctatataaac tattttagta
    18241 tttggtctca ttgcttcttt tacattttgt ggatttactg catctacaaa tgtaacttca
    18301 actccaaatt tagataacaa ctcagacatg aataatttag tgtgtgaaaa tattccatct
    18361 gaactaacta tatggtcacc actttttacc aatgctaata tagtagatgt tattgccccc
    18421 atccctgatg tactagatat ggcactttct gcattttcaa gcatagccaa cttagcttct
    18481 aactctgtaa gagtaggatt acactctctt gtatacacat atccccatgt catacacaac
    18541 tcttcaaaat gctctactgt ctttgcagca aatgttgctg tttgacatat tggtgtagcc
    18601 aatgcacctg ttgttgggtc tgcactatgt ccccaatgta ttatttttgt ctctaaatct
    18661 tgattaatat tgttactcat tttgatttcc tcccattttg acttatttat acaacgtttt
    18721 ccctgccaaa tttaatcaat ttagcttagt cttaatacat tttttcaagt atactttttt
    18781 atttgttata atttctaaaa atatgacact tattttgttt ttttacagtt ctaattataa
    18841 actctatagt aactatagag tcaatatgtt tttgatattt tttttacaat gtttaaaata
    18901 gtcagtacaa aaataggtat atcttagaat aactaaagtc atcctaagat atacctattt
    18961 ttatatcaca atataaataa ttacatataa gcattagttt ttttatcata aatagatttt
    19021 tcaagattta tcatcttttc ataaatatat tatagttaaa tattttaata ttacctaaca
    19081 tctacaataa aatatactct taaaataaaa ttatataatt aaaaatactc tataaaagct
    19141 aaaaagtttt ctattcgcta catctaaaaa taattagata gaggtataaa tgtatttagt
    19201 ttatttatac ctctagtctt ttataaatta tatctctact aaattgattt tttagcacga
    19261 ataagtgtgc tcttggagat accagtcatc ttcacaacct ctctatatgg cttagaattt
    19321 aataacccca atgcatattg tatctgttga ttgctgtatt tctttggcct accatcttta
    19381 aagtcctttt tctttttagc aaattctttt cctaattgag tacgttctat tatcatattt
    19441 ctctcaagct ctgcaactgc aagtaatgta gtcaaaaaga atttacccat tgaagtattt
    19501 tctaaaagac ctatatttaa aatatgaaca cttacttctt tagcaaataa accttctatt
    19561 agttgtatcc cttctgatgt acttctagct agtctatcca gcttagttgc aacaagtaag
    19621 tctccctttt ttagagatga tataattttt tcaaatttag gcctgtttgt agtagtgcct
    19681 gtataagttt cctttattat tttagcatca ttatatttat tcaaaatttc ttgctgttgc
    19741 tgatacaaac tgttgttgtc tgtttgattt tttgtactta cacggcaata tccatatata
    19801 ataatcatca cttcctaaca taaagatttt gtacagaagt tacccagaag cttgttttta
    19861 cttatcttta tccattttac taaaacgatt tttgggtgtc aatactgtta acttttgaca
    19921 ccataataat tcctttataa tttgtttgac tatgtcaaaa attaccaata taatgaaatt
    19981 aatgagttta tacaaattgg aggaaataat atgaatagtc tgttaaaaga agcaatagat
    20041 gaattaaaaa acatccattg cggggaagtt tttttattaa aagaattgtt caaaggctat
    20101 gaatggaaca ggttggagat gaatattaga ttgaaattag gaaaactttt tttgtatgaa
    20161 gtggtaacta atcccaattt aaatgtagag gtcatcaata aaaattctgc ttatcagcaa
    20221 atgtataaaa aaaaatagtg acttaaatgt atataatagt ataatcttct tattgattca
    20281 aaagttaaaa cttttaatac aaaacaatca ttctatttta acatttatca atatgtctaa
    20341 atttatataa ttaacacata cgaatagtat tgtttaaatc acattattta agatagataa
    20401 atcttaaccc tactccagca taaatactaa aatagggctt agaattatct atatttttat
    20461 cccataaaat gcttagctct tcctcttgat tgaacatata tatctgggga aatacaatag
    20521 aagcgtaaat ttataaaatt tccaaagtca gaaaacttca gttcaaactt aggtatacca
    20581 aaactttcag gtgctatttc atcaacgcca aaatagatga taattccatt atctgtaata
    20641 taaaatgctt ggtcttcagg tataactaac tcaacattag aataatacat ttctctattt
    20701 tcatttattt gagatttaat gtaatcagta attatattaa tataatcaac tccatctcta
    20761 aaaatgtcat taagtaaaag ttcttttcca gttgtcaaat ctatattgta attattcaat
    20821 gtattgtatt taggcccata gttattagca aaccccataa ggtttaatat catactcagt
    20881 acataatttt tattaaaagt aactgcgtaa ctggtagata cccaatagct ttgttttgga
    20941 agtgaatttt gagaagctgc gttattatat tctcgttctt cttcctgtaa gccattttta
    21001 aaattattta cagtcattct tacagcattg tttatgttat ttaaaataac tgggtttaca
    21061 tacgtggatt gatttctaat attgtatata acaggatact ttacatcata tgaaaaatac
    21121 ttacttcttt caaaatcttc attaaattgt acatataata tattatatgt acaggtattt
    21181 gtagattgat aattttccat taaaatcctc ccccttttat aaaaaaatca gatacaatat
    21241 aatatgctta aaacagtaat aatgttaata gtaaatgtaa agaatagaaa gtatctaaaa
    21301 cagcaaaaaa tgactaattt tgtggtataa tacataggat tgagagttat tttataggag
    21361 gaaaaatatg ttattattag cagataaatg gaaagattat gaacttatag atatgggaaa
    21421 tggagaaaaa ttagaacgtt ggggaagtta tgtacttaga agaccagacc cacaggttgt
    21481 atggccaatg gaatctgaat gggctttatg gaaaaaccct catggacatt atcacagaag
    21541 caataaaggt ggaggtcaat gggaacacaa aaaaagatat ccagaacaat ggactataaa
    21601 ttataaaaac ttaaagtttc acattaaacc aactggcttt aaacatactg gattattccc
    21661 agagcaagca gctaactggg attggatgat agagaaaata aagaaagcta acagacctat
    21721 aaaagtgttg aatctttttg catatacagg tggagctact gtagcatgtg catctgctgg
    21781 tgcagaagta tgtcatgttg atgctgcaaa aggtatggtt aattgggcaa aagaaaatat
    21841 agaattatca ggtcttaaaa atcaaacagt aagatttata gtggatgatg ttgtaaagtt
    21901 tgttgaaaga gaaataagaa gaggtaaaaa atatgatgca ataataatgg accctccttc
    21961 ttatggaaga ggtcctaaag gagaagtatg gcaaatagaa gaaaagttat acagttttgt
    22021 agatttatgt atgggagttt tatcagataa ccctttattt ttcttaatta attcttatac
    22081 aacaggattt tctccaatag ttcttgaaaa tgtattgtct acaacaatag gtaaaaagac
    22141 aaatacagga gatatatacg gtggggaatt aggaatacca gcttccagag atggtaagat
    22201 acttccttgt ggtatatttg gaagatggga gaaaaaataa tgataaaagt catatatgaa
    22261 gataaccatt tattagttgt agaaaaacca gttaacatat tgtctcaagg agataatact
    22321 aatgataaag atatggtaaa tcttttaaaa gactatatta aaaaaaagta taacaaacct
    22381 ggaaatgtat atattggttt aatacataga ttggatagac cagtaggtgg agttatggtg
    22441 tttgcaaaaa catcaaaagc agcatctaga ttgtctgagc aggtaagaag taagactttc
    22501 aaaaaaactt atctagctgt tgttcatggc aagataaaat ctaactcaga tatactaaaa
    22561 gattttttat ataaaaataa aaaaactaat atggtaactg tagtgaaaaa aagccataaa
    22621 gatgccaaag aagctgaact taactataat gtattagatt ttaaagaaaa tctaagttta
    22681 gttcaagtta atttaaagac tggtcgttct catcaaataa gagttcaatt tgcaagcaga
    22741 aaacatccat tatacggaga ccaaagatat ggcaaagaaa taaataagat tggacaacaa
    22801 atatctcttt ggtccaataa gatagaaatt tgccatccta ctacaaaaga aaaaatggaa
    22861 tttacatgtc atccacctga caaatatcca tggaatatat tttaaatctc aaatgaggtg
    22921 attatatgag taaaaaattt tcaataggag aaatgtctaa acttcataaa ataagcatac
    22981 agacactaag gtactatgac caaatagatt tatttaaacc tgttcatgtt gaccaagaaa
    23041 gcaattacag atattactca attgaccaat tttcacaatt agatattata aaatatttaa
    23101 aatatttagg tatgccttta aaagaaatta agtcaaagct tgatgaaaat aatgaagaaa
    23161 ttctaaaatt actaacaaat aaaattaata tagtggatga aaaaattaaa gaattagagc
    23221 ttataaagaa ggtactaagc acaaagaaag aaactatgga aaaaggtatg aaagtagatg
    23281 aagttggtaa aatagtgaga aaacatattc cacgaagaag tatcttatct atagagtatg
    23341 aagaaggatt aagtagtgaa gaaactatgg aactttccag aagacaaata gcaaatatat
    23401 tagaagataa tatatctgtg ttctatggtg gagtaagtgg acttgtatct atagataaat
    23461 ttttaaaaga agataaagtt atttatgaca atagttttgt tactgttgaa agagacttat
    23521 ttgatataaa atcacaaaaa catataacag aaatttcatc tggtgatttt atttgtatga
    23581 catataaagg gtcttacaaa gaaaattata ccgcttttaa gaaactggtt gattatgttg
    23641 aatataaaag aatacctatt gaaaattata tatatgaaat acctataata gaccctctgt
    23701 ctacaaacaa cgaagaggaa cttctaacag aaattcaaat acaagttaaa aagagagaaa
    23761 ttgacttaag atgtctagtg tagtaatcta gtttacttac acatcttaat atagttgtct
    23821 attatcaaca tatgattttt ctagatagtg attcctaaca gtgagatttt caaaaaatag
    23881 gaggaaatat ggctaatgct aattccctcc tatttttaat taatccatat cattttaatt
    23941 aagccatgtc atcacgaagt gcatcaataa tattttcttt ttttatctta ttaatagtat
    24001 acaacattgt aataaatact ataaataaaa cactaaatat actaattcca atactaaacc
    24061 atggaatcac aaaatcaata tcatctgtaa ccattacttt atgaattagc catgaagaaa
    24121 ttactgctat aggaagtcca aagaacaatg ctctcatgcc ataaaaagca cactcaaaat
    24181 tcatcatctt ttggaaatca tgctcagaca ttcctacaga gcgaagcatg gcaagttctc
    24241 tacgacgtaa cttaatatta gttgaaattg tattaaacac attggcaatc gaaatcagag
    24301 aaatcataat tatgaaagta taggcaaaaa cattggcaat aaaaatgtaa ttacggttct
    24361 catccatcat tccatacata ttgtacagat tgtactcatt agtaactccc tcactctcaa
    24421 taatttgctc catttctgca actgactgag taggattttt cgattgaaag cttaaacttt
    24481 caattcctgt agaaacacca ggaatctcaa acttatcttt ggctgaataa ggagccaata
    24541 ctctgaagct tgctttcttc acatctgaac ttctgattcc tggaggagaa tcaggtggca
    24601 ctactttgac aaatgaaata ttcacatttt gtctctcagg tatctccaac ttgccattag
    24661 tttcaggagt gagactaaca ttcatagaag aactgttgaa aatatcaata atattattat
    24721 cctttgttac catagaaaca gcaatcagtt ttgcattttg tccagtatat tcttctgctg
    24781 gtaatccaag acttttaata atattcagat aagttctatc atcaagaaat tgcatatcta
    24841 ctggtaattc aagcatttca ctcatagaat gtgaaccctc atagttcaaa taatcgtctg
    24901 taagctcact tactttggca acacatgaat aggtcataag tttctgatac aaaccttcgt
    24961 aaacaccatt tgcagttttt agcttatcgt aaagcttcaa catttcgttg tctttcatac
    25021 cttgtgtaga aaaaataata tcctgatcag taacctctga cctctgattt gacatctgtt
    25081 ttaggtctgc tactaaagca cttgtagata taaataaaac tatgcttaaa acaagcgaca
    25141 atacaatact tcgataacgt ttcttgtttc ttttaaagtt tttcatagca agaactccct
    25201 caagaccata aactcgctgt gttagttttg atgtcttcac agatttagat tcaattttta
    25261 cctcatttgt ctgacgaata cactccatca ctggtgtgtt ggcagccttt cttgctggta
    25321 tgtaagcaga aattaagatt gtaaccatac ttaccactgc tgcaacgatg attgcaggga
    25381 tagacaatgt taatgtcaac ggaacgttta catagagaat atttgcaaag tttttagcta
    25441 tgacagaaat cacaagtcca atactgacta taccgattgc aacaccaatt ggtataccaa
    25501 tcgcaccaat gcaaattcct tcaaatagca ccgaatttcg taactgtttt gctgtagctc
    25561 caacagatga aagtattcca aattgatgtg ttcgctcgtt caatgacatg ttaaatgaat
    25621 tatatattag aaaaattgag cctagcatga ttatggcaag cacaatgcca ccaaccgagt
    25681 acaaaaacat attgaacaaa ttgttatcag aaacacctat gaagcgcaac acattgtcat
    25741 tgaaaatgga agcatggtct ttagtgctac ttgtgtaaga gcgaatctga tgtggatttt
    25801 tcaatgtgac aaaaaggcta agactgtcag tcttgacttg tttatcttct ttggttatca
    25861 aggtatatcc tggtgcagaa gattcttcaa atacgggctt tctacagata cccacaactg
    25921 tataagtttt cttatcctgt ggcacaaaaa cttcactccc agcagtgtag gggtcactct
    25981 gaccaagctt ttcattttca ctcattcgtt tccctacatc caaagaaata gtatcaccta
    26041 ctgcaaattt gacaccacca tctgtcgcaa ctttacttga aacaagaatc tctctactat
    26101 tttcaggtaa tcttccagaa attaaagtta taggcaaagt atcaaaagct tctttgctaa
    26161 atccagcaat aaaaagatat ggtttatctg gatttctgtt accttcaagt gttgcatagc
    26221 caatattttc aaatgttgca gtatttgcaa cttcatcatt gactctttgt tcctgtacaa
    26281 aagaagaatc cacatccaaa aactggacat gccaatcacc atattttata atagctccat
    26341 ttgtcatata gttcatcaaa gaaactccaa aggtagtaac tgctgtaatc atagcagctg
    26401 acagaacaac tcctataatt gttacaagag ttcgagtgcg attctttttc aatccttgca
    26461 gagcaacttt gttaaaaatg ttcattaacg attcaccttc ctctcatcac gcaccacttt
    26521 tccatctgaa atacagataa ttctatctgc ctgtaaagca atgttttcat catgtgtgac
    26581 aataatgaga gtttggtgat atttactatg gctctctttc agtaactgga taatctcttg
    26641 tccattttta ctgtctaagc tacctgtagg ctcatcagca agcataactg ctggtgcatt
    26701 catcaatgca cgaccaatgg caacacgttg ctgttggccc ccagaaagtt gatttggtaa
    26761 atgtgttttt cgttctttta aaccaagtaa ttctaacaag tcatttaacc gttcttgatt
    26821 gaccttacgc ttatccataa gtataggcaa tgtgatattt tccactacat ttaatgtggg
    26881 tatcagattg tgaaactgat aaatcaatcc aacttgtcgc ctacgaaaaa tagcaagttt
    26941 ttcattgctt tggccatata catcttgccc ctccagatat atctttccac ttgttggtac
    27001 gtctactcct gcaatggaat gtagtagtgt agatttacca gaaccagaag aaccaatgat
    27061 tgcagtaaac tccccttttt caatagtaag tgagacatgg tcaagtgcag taaccttatt
    27121 ttcattctta ccataaacct tacataaatc ttcaatcttt aaaaacgcca ttatataagt
    27181 ctcctttcat attttataaa tatatcatag aactttcaac ttacatttaa gtgacattta
    27241 aatgagagat tcgtcacttt ggaaaacgaa taacaaatat tgcaccacct tgtgggtgat
    27301 tttgtgcagt aattgttcct ccttgtctca taataatcgt cttacaaagt gccaatccta
    27361 ttccataacc agctgtgctt gaatttttcc cacgataaaa tctgttaaat agacatggta
    27421 agtcttcttt tttaaagcct gctccgttgt catgaatagt aagttgagta aacaaaaagt
    27481 tgtcctcaca aacgatatca atttttccat tatcacccac actctccatg cagtttttaa
    27541 atatattttg aattgcttct gaaagccaat ttaaatcacc caaaatcctt actccttttg
    27601 gtatatcaat atgtaaagtg atattgtgca gttccatggg aatcaaaagt tgatgaagtg
    27661 cagaactaat caaattattc acatcaattt gttctttttg aaagactaca atacctgcat
    27721 ctaaacgtga taattttaaa agggaagtaa tcagccagtc cattcgtata agtaattcct
    27781 ctgtttctcg tatcaactct tttctctcat cttcatcaga agtattctct aacagtgaca
    27841 aaataagagt tactgatgta agaggagtgc gaagctggtg ggctatgtca gctagtgagt
    27901 cagcaaggtg ttctttttct tttttcagtg cgtaattttg ctctctaata cgtaacgtca
    27961 ttttagttat ttcactttgt agaatagaaa gctcaccctc atctgattca gcaatataca
    28021 gatggttagc attatgaagc acaagattaa tttgttctga aatctgtgca atacttttgt
    28081 atcgattttt agtaaacaca aaaaatgcta ttccaaaggt agtggcagaa acaatagaaa
    28141 gtattccagt cataatactg attgcaaatc ccagggctac agtgagaata gtaattaata
    28201 agaataaaat agcaaatttt cgaaactctc tatttcgaaa cataacttcc ccccaatcta
    28261 taccctgtcc cacgaacagt caaaattatt tgtggacttg aagggtcatc ttctatcttc
    28321 tctcgcaagc gtttgatgta cacagtcaat gtgttgtcat taacaaactc acctgccgca
    28381 tcccacaatt catcaagtaa tcttaccctc gtaataatac ttttaggatt gctaataaac
    28441 accaataaca aacggtattc taaagctgaa agaaaaacct cattgccatt ctttttcaca
    28501 acaccggttg ccgtatctac ataaagccca caaatttcaa aagttgaccc aaaacgccca
    28561 ctttttcgta gtgctgttct aattcgcgca atcagttcac gtggacgaaa aggtttagta
    28621 atatagtcat ctgcacccat attcagtcca gtaacaacac ttgattcatc accagaagcc
    28681 gtcaaaaaga taacaggaat gtcttgcttt tctttgattt ctgtgcaaat cgtaaaccca
    28741 tttccatcag gtaaagaaat atcaataagt gccaaatcaa atttattctt agcaatctct
    28801 acaagtgctt cacttcttgt ggatacatgg gttactataa atccttctga attaagcaaa
    28861 agaataagat ttttggcaat tgctttatca tcctcaacta aaaatatccg tttcatttac
    28921 tttcatcctc ctttatttta ttagttttat atattccagc agagcaatag tacactacta
    28981 ttttacttat cattacacaa ttttcagtag tttcttttgt tcttatataa tccatgcata
    29041 atacctccat tgatttatta tatttcttat aacataaata cacaagataa gacaaaaaac
    29101 ataatgtaag tgcaagtttt ttaactcact aacttataaa catacactcc tactaacact
    29161 actttcttga tgacacatct tacaagctta tattcataca tcaatgaaaa attaaattta
    29221 tccatttatt aaaataaaag gcaatagctt ctatagctaa tgccctttat cttaaaatga
    29281 tttaaatact atacaatttt tataaatggc tataaataaa ctcgtataga atataaaatt
    29341 tatctacagt cttttgttat acaaaattta taacctctta tagaacaaat ttaccacttt
    29401 gtaaacttat cacttttact cagctatatt ataaactttt aatttatctt tgtttaaatg
    29461 tttcttctta acttctacta aagcttttag cgtatccaaa gatgtcatta tttcagtaga
    29521 aaattcaatg gctgttcttc tcatcttaaa tccatctctt gtagagtcat ttcctttagt
    29581 tggtgtattt attactatat caacttgttt atttcttata gcatctaata tgtttggtct
    29641 aggctcttca attc
//
LOCUS       DAMJYN010000044        29485 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.045, whole genome shotgun sequence.
ACCESSION   DAMJYN010000044 DAMJYN010000000
VERSION     DAMJYN010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 29485)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29485)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29485
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.045"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            81..902
                     /locus_tag="PC466_002164"
     CDS             81..902
                     /locus_tag="PC466_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HDF2769546.1"
                     /translation="MIKKEISNFRGSSDYVVSPELMASVNVAIALEKPLLIKGEPGTG
                     KTMLAQAISNELKKDLVIWNIKSTTKAQEGLYVYDTVQRLYDSQFGGEGVDDISKYIK
                     YGKLGEAFSSNQQVILLIDEIDKADLEFPNDLLWELDKMEFYINETKETVRAKQRPIV
                     IITSNAEKELPDAFLRRCIFHYIEFPDRDMMEEIVKVHFDKVEEHLLEQVMTTFYWIR
                     SLKDIQKKPSTSELIDWIQALTLSGMPIEKIEKEVPFAGILLKNNEDIESMQRHL"
     gene            923..2119
                     /locus_tag="PC466_002165"
     CDS             923..2119
                     /locus_tag="PC466_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HDF2769547.1"
                     /translation="MFIEFFYLLRSRGLNISLNEWMTLIEALDKGLCYSNFSNFYYLC
                     RMILIKSESDFDKFDAVFLEYFKGIEHQEEIPEEIMNWLKKPDIDLEEFERLEQNPNI
                     NLDKLRAKLEERIKEQDSPHNGGNYWIGTGGTSELGHSGKGQTGIRIGGNSTYGRAVL
                     EVAGERKYRDFRDDEVLNMRQFQVALKRLRQFSTRIDAPKTELDLDKTIEETCNNAGY
                     LKLFFEKPRKNTVKLLLLMDSGGSMRGYSTLCNTLFQSVSKSNHFKDVKIYYFHNCIY
                     DRLFTTPECWLSKSINTEWILKNIDKNYKVIIVGDASMSPSELLHIGGNYRGPYNYTP
                     GIEWLKRFKRKYSKIVWMNPELRDGWDSINYWYQTQRMIQSEFNMFPLTVKGLEKALK
                     NLMLSR"
     gene            2285..5683
                     /locus_tag="PC466_002166"
     CDS             2285..5683
                     /locus_tag="PC466_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HDF2769548.1"
                     /translation="MIIINYELIVKYNGDILRLEEELGVSVEILNSSYAIITSSNEED
                     VNTLLTYPEIEFIEKPFILQTQDVQSFSSTGITGFKNRTGLTGKGTIIGIIDSGIDYT
                     LPVFRDSDGRSKILYYWDQSIQGNPPEGFREGTLYTNEDINNAIDGSMYIPISTTSLH
                     GTHVAGICATIASDARIIVVRVGNIQTDIFSRSTEFMRAIKFILDRALELRMPVTLNI
                     SYGSNEGSHRGTSLFEQYIDDMCLFWKNNIVVAAGNNADKGGHKRIRLQNNITEEVEF
                     IVGEGERILNINIWPDFVDDFSVHLVNPSNNQTQAISLTSGEIRNTLGETRITGYFYP
                     IAPYSLTRRVTLQLSSNTQITPGLWKIVFEPIDIVTGNVNIYLPTSEGLNRNTRFLIP
                     TQELTVTVPGTASRVVTVGSFNSRTDIVSIFSGEGDTQLGVFKPDLLAPGEDIISFLP
                     GGTSGALTGTSMATPHVTGVCSLFMEWGIVNGNDLFLYSQKLRALLLKGARRLSNQSY
                     PNNSSGFGFLNLSDIDLYTLSSINQDLETEDIGYRSINKSFKDEENRYKFIDGYNIQI
                     HNDLENEIYISKNASRQSGILSGIDVVHTPEFEEELAGLGMSQNFFKISDSLGVLSIN
                     NTDYSSIQRVLQLPSIIRTVSTTKMTLLGEINRGTFGGVVATEEMGVNFFKNNPNINI
                     TGRGTLISIADTGIDYLHPDFIYPDGTSKIVYLWDQTKEGTPPDGFYIGTEYTREDIN
                     RAIAENDPSLSQDEVGQGTMLSGICSGLGNVNSEYAGIAEDSELIIIKLGKIDGFYNS
                     AMLFAASQYAYKKAFELRRPLVINMSLGTSSLAGLTNRSNSEKAFFTRGLCITAGAGN
                     EGNTQTHTSGIIPHVGGSVEVELELNEDEEELSLELWLNRPDKADVIIVSPTGEESKS
                     VGISNYNKVTGLFDLEGTEYSITYIYPTTFSGQQFTNVTLKNAKRGVWKIRLVGVYII
                     TGRYNLYLPNRELLKSGTRFREVDPFYTINYPAIQDDLITVGAYNTINGSLWQSSSRG
                     PTIEDRLKPDIVAPGVNIIAAYPGNTYATITGTAAASAHAAGAAAMYFQYTFVDGRYP
                     NQAYVQKIKTFMQAGARKDSNTVYPNTNSGYGLLDVRGMFDVLR"
     gene            5693..7366
                     /locus_tag="PC466_002167"
     CDS             5693..7366
                     /locus_tag="PC466_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family peptidase"
                     /protein_id="HDF2769549.1"
                     /translation="MEKSYCIIYQGDIESALQENGINRYMVLNSQLAVIYVPVDFDET
                     ILNNIIQVAWWEESEPMSSLIEITNNVNNGETITTAAETDYIYENPYNDITGRGILLA
                     VIDSGIDYLHPDFINDDGTSKVLYLWDQEANTNPPPEGFIFGSEFTRSQLNIAINRND
                     GSLSQDNIGTGTLVSGILAGNGRINSQYRGITTESDLIVVKLKSYTDTYYAGRINYSV
                     SDFLAAITYVTNIARTENKPLIINLTIGVKSSAVATTSILDTFNILSSAGVVVVSGAG
                     NQGNTDIHYSGRFSSVGEVQDVIIQDGDDYALDITLNTNGPDKVGAQIISPSGEVSHD
                     IRYSPDFYIYRGKFNLENTTYAMRFIYPYITSGKENLEIRLRDIKPGVWILRLTSELI
                     ISGEYDIYLPNKNLIAPDTRFLDPDSVATITMYAASDDVITVGTFNNKTDSMWIGSSK
                     GPIRGRGIKPDIVASGVDIISTYKNGTYNTGTGTGVSSSIVTGVLALLMEYLEKQDNV
                     PRLSLFTQVLKTYLILGATKLEIYTYPNVSQGYGILNLKNTIQQIANTL"
     gene            7640..7834
                     /locus_tag="PC466_002168"
     CDS             7640..7834
                     /locus_tag="PC466_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3787 domain-containing protein"
                     /protein_id="HDF2769550.1"
                     /translation="MESKKARALKGKDNKRLKSSLLVGNESTAAWADVEKLKPHSKVS
                     IPSIKGVEEAKDWVDNGSKL"
     misc_binding    8003..8236
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            8313..9710
                     /gene="asnS"
                     /locus_tag="PC466_002169"
     CDS             8313..9710
                     /gene="asnS"
                     /locus_tag="PC466_002169"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HDF2769551.1"
                     /translation="MQKEFITVKELYREKEQYIGKTVKVAGWIRTSRVSKNFGFIELN
                     DGSFFKNMQIVFDEKVENFKEVGKLAISSSILVEGELVSTEGAKQPVEIHAKSIVVEG
                     ESDSSYPLQKKRHTLEYLRTIAHLRPRSNTFSAVFRVRSIAAYAIHKFFQERNFVYAH
                     SPIITGSDCEGAGEMFRITTMDLNDIPKTEDGKIDYTQDFFGKEANLTVSGQLNAEIM
                     ALSFRNVYTFGPTFRAENSYTGRHASEFWMIEPEIVFADLEDNMELAEDMIKYVISYV
                     LENAPEEMEFFNSFIDKGLLERLNKIVNSEFIRITYTKAVELLIESGHEFEYPVEWGC
                     DLQTEHERYITEQIYNCPVFVTDYPKDIKAFYMRMNEDGKTVRAMDLLVPGVGEIVGG
                     SQREEREDVLLDRINEMGLREEDYWWYLELRKFGTATHSGFGLGFERIIMYMTGMSNI
                     RDVIPFPRTPKNAEF"
     gene            complement(9883..11058)
                     /locus_tag="PC466_002170"
     CDS             complement(9883..11058)
                     /locus_tag="PC466_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDF2769552.1"
                     /translation="MNLEKIKKFFGFPLDKKHKENVEKELCNYLYHTGKIICIIIVIS
                     QIIMMISISAREGGPFATPRRQWYFYMYVTLFCVSSVFMFVFSYLWNKKKDCCTFYIN
                     LWIIYVTFFCLWGCVITLLDQLGGNDLSVFSYIMLAAAAFSVLKFGESVIVFGGCFLF
                     LNLFLPGIQTIPGNEFSNIVNTFFITSLAIFVSTMLYRNRVFTYYDKLLISQQYEEIS
                     HINNLLNDKVMTDDLTKMNNRRYLEDILQKKLISHANQEPITGMMIDIDYFKQFNDNY
                     GHQKGDYCLQNIAKVILDFTSSENEHAIRYGGEEFFICIFNCDETDAKLKSECLRKII
                     ESCNFERDDVPLKCVTVSIGVYTKKIEKAITLNEFISNCDKALYTAKEQGRNCVAFY"
     gene            11477..12841
                     /locus_tag="PC466_002171"
     CDS             11477..12841
                     /locus_tag="PC466_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HDF2769553.1"
                     /translation="MGEKKINNMNYSHNNYSKKTGEPTRKIKNSHITLKSKEEKICSS
                     CNKENNTKDNYCKFCGNELYEIASLRPLETKLDLKSKIKELSYHANKRGVFLTTFTTI
                     FILFIIALIFKAIITIQFNDISYLINPAHIILALNLGQISVSMSTMMGSGFINANIGL
                     LILLIIPILVLLISNLIFMRKRCRDSKTVLANSLGVGIFYGLVLAILSIFTNVKTSSH
                     SMLEYGYALEYSYEFFSVLLNGFVLGFICTYITTYKKSYEKENMYLSLFSNSIRTFIL
                     GYVLVLVILLVLTISDSSYLNELDMSSYSNGLNLFTILPQIASYMWAFANGISVTIIN
                     STVSMFTLSSSSLFGDTKLMFYAMGALSMLILLLNGYKLRFKYNTDSIRPIIVFSIYY
                     AFLMGILALFSTFILDSNINFFNTTNYGTTLIMQFKVLQAIVISFVYSFVISLIGYKL
                     NSAD"
     gene            12863..13354
                     /locus_tag="PC466_002172"
     CDS             12863..13354
                     /locus_tag="PC466_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HDF2769554.1"
                     /translation="MEGNTNNKVDDKFSKVKKKFGSGKFKVELYKEKSKLNREIDDIQ
                     EKKAKIFLEMGILTYQKIREDSINDNSFDKFCDELLELDKLIYEKNMEINEMEMAESN
                     VTCECGYVGNVNDKYCAECGKKFELENECDDFIICGYCESEIDTEAEFCPCCGRKIIM
                     DLE"
     gene            13627..14298
                     /locus_tag="PC466_002173"
     CDS             13627..14298
                     /locus_tag="PC466_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HDF2769555.1"
                     /translation="MLDKVKGRLIVSCQALENEPLHSPFIMGRMAKAAMEGGAVGIRA
                     QGVEDIIEIKKVTGLPVIGIIKRNYEDSDIYITPTKKEVDELLTTGCEMIALDATNRV
                     RPNNEDLKELIKYIKENGVLVMADISNYDEAIKAQEYGVDCVSTTLSGYTPYTKTLEG
                     PDFVLMERLVKDLEIPVIAEGKVNTPQDLKKVFELGVHSSVVGSAITRPQLITEKFVK
                     AIEIN"
     gene            14383..15249
                     /locus_tag="PC466_002174"
     CDS             14383..15249
                     /locus_tag="PC466_002174"
                     /EC_number="4.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003452648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate lyase"
                     /protein_id="HDF2769556.1"
                     /translation="MKGIYSALLVSFDKEGNINEKGLRQIIRHNIDVCKVDGLYVGGS
                     TGENFMLSTDEKKRIFEIAKDEVKEEIKLIAQVGSVNLKEAVELAKFTTDLGYDAISA
                     VTPFYYKFDFEEIKHYYNTIINSVDNRLIIYSIPFLTGVDMSLDQFGELFENEKIIGV
                     KFTAADFYLLERMRKTFPNKLIFAGFDEMMLPATVLGVDGAIGSTFNVNGVRARQIFE
                     LTKNEKISEALEVQHVTNDLITDILGNGLYQTIKLLLEEQGVEAGYCRQPMKEATDEM
                     KSRAKEIYRKYF"
     gene            15282..16784
                     /locus_tag="PC466_002175"
     CDS             15282..16784
                     /locus_tag="PC466_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003462875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
                     /protein_id="HDF2769557.1"
                     /translation="MVGFTWIDFAILVVYLLAVLFAGLLFSKKEMKGKEFFKGDGTIP
                     WWVTSVSIFATLLSPISFLSLAGNSYGGTWILWFAQLGMFIAIPLTIKFFLPLYSRLE
                     IDTAYEYLEMRYESKGLRVLGALMFIIYQIGRMSIIMYLPSVVLAGLTGIPVNVLIVV
                     MGVIAIIYSYTGGLKAVLWTDFIQGMVLIVGVTGTLFYLIASINGGFGTVMDTLTTGH
                     KFLASNEVMFDKNILSTSAFIIFIGAGLNTFSSYVSSQDIVQRFTTTTDIKQLNKMTY
                     GNGVLSMGLATVFYLIGTCLFIYYTQNPDLAQTVQQDQVFASYIAYELPVGITGILLA
                     AIYAASQSTLSTGLNSVATSWTLDIQTIITKDISMEKQTKIAQYISLGVGILSIAVAI
                     VLANGEIKSAYEWFNSFMGLVLGVLAGIFVLGAFCKKATKMGAYVGFIVSAILVVYLK
                     YRMPEVTSWAYSLITITTSVVVGTIVSAIEAKVKAKVSLPKAETTVYYEK"
     gene            16914..17366
                     /locus_tag="PC466_002176"
     CDS             16914..17366
                     /locus_tag="PC466_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HDF2769558.1"
                     /translation="MIFGNINHSKTYSTLHEDLLRCFEYAKDNSLIDYEKGTYTIDGD
                     DIFVNIVEYKTCEKEDRFWEAHKKYIDVHLMLDGCERIDINFIENLEQKIYEEKGDFL
                     PLDGKNNGYMELRKGDFLVCYPEDAHMTGIKVLEKENIKKAIFKVLVR"
     gene            17526..18329
                     /locus_tag="PC466_002177"
     CDS             17526..18329
                     /locus_tag="PC466_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769559.1"
                     /translation="MENIDVFLLIGQSNARGLGNPKESIIPNENCFEYLSTDEIINMR
                     CELETSEGDGTIAPAFSNEWNKLTGNKVCFIHNAKDGSRIKNWNHDNNWFLNDTIEKF
                     NTGCTTLSKHYNIENKYVIWIQGESDAKYGSDALYYKESLKKIAYRLKEECMIDKMFV
                     SLTGYWLGEDEYFIRTRRIAAAQESACNECDILCVGSKIAMQFHDRGLTIDDVHYTQE
                     GLNMLGEDLCKNIYKYHITKEKSVLSDTIDLSEARKYICELEKISKRFV"
     gene            18387..19274
                     /locus_tag="PC466_002178"
     CDS             18387..19274
                     /locus_tag="PC466_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HDF2769560.1"
                     /translation="MKNYVCIDVGGTSIKYGFIREDGFIIDKSSLDTEAKEKGGEGIL
                     AKIKDIVKKYIEENEISGICISTAGMVDPVEGKILFALEELIPNYKGMQLKKEVEKEF
                     NIKCEVENDVNCAGLGEVWLGAGRGATSSICLTIGTGIGGCIIINNKLINGFSNSAGE
                     VGYMNINGSSFQELASTSSLIKKVAKIKNLNEKDLNGKIIFDLAKNNDEDCLKELDNM
                     IKSLAVGIANICYVINPEVVILGGGIMAQEKFLKPKIDKALKEVLIERVYKNTNIEFA
                     KRQNDAGMLGALYNFLNKI"
     gene            19293..20141
                     /locus_tag="PC466_002179"
     CDS             19293..20141
                     /locus_tag="PC466_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDF2769561.1"
                     /translation="MSILEQLESPTFKVTKSDKLLIAYIKENIDDVFYKPISQIAKES
                     NIGEATITRFVKKMNFNGLQDFKVTLAQEISTINKKNIINKNIQNDEPALDTAKKLLS
                     SNVTTLENTVEIINSKDVHDCARLIINAKKVYFIGIGYSGIIAQDSNYKFMRIGLNCV
                     SFDSSHTMIMMSSIMEEGDLIIAISHSGETEEIIKTVKLARANNAKIISITENKNSEL
                     KDISDVHLSYVSGETVLETGSISSKLAQFFIIDLVYTQVVKELSNEAIERKIKTTNAI
                     KLFKNE"
     gene            20204..20893
                     /locus_tag="PC466_002180"
     CDS             20204..20893
                     /locus_tag="PC466_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HDF2769562.1"
                     /translation="MSKLKDYNIDKVIIFNNLSTKTKNQLKEKAKLKRLQKKEILFYE
                     KDSLDSVYILLEGKVSIFKISENGERKVIFILNSGEVINDITFDSSKNSTVGCEAFEN
                     SIVAYYSIEEFLEIMQNDFQLTKDIISYMERRIRRLYRQLKNSISIKVDKKLAAKLYR
                     LSREFGVCCGEWTLLNVNITVTYLADMLGCKRETVSRMIKVLQKEELIKIDNKGFYVK
                     ETELSRYFKNN"
     gene            21283..22290
                     /gene="asrA"
                     /locus_tag="PC466_002181"
     CDS             21283..22290
                     /gene="asrA"
                     /locus_tag="PC466_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfite reductase subunit AsrA"
                     /protein_id="HDF2769563.1"
                     /translation="MKLKLDSSKFNEGLNYLKKDYKIFAPVLIPFKGTFSDTDVIRYK
                     EVNAFEEMEFAKKANFSPKEVVLPINQVLFYFTEKEFKESDLDNKKILIFLRACDING
                     IKRLDEIYLNNGEEKDYFYKNIRDKVKFALVGCKESFRNCFCVSMDSNKTDNYSIGLN
                     IEGDTLYLDIKDSEFEVFNGEATEFNVDYVTDNLISVDVPENIDSNEIIGNSIWDEYD
                     TRCIGCGRCNFVCPTCSCFTMQDIFYKENENVGERRRVWASCQVDGYTDIAGGNSFRK
                     KQGERMRFKTMHKIHDFKKRFGYHMCVGCGRCDDACPQYISFSKCIEKINDLVISKEE
                     V"
     gene            22291..23082
                     /gene="asrB"
                     /locus_tag="PC466_002182"
     CDS             22291..23082
                     /gene="asrB"
                     /locus_tag="PC466_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfite reductase subunit AsrB"
                     /protein_id="HDF2769564.1"
                     /translation="MNPYIPVSAKILDIVKHTDKEWTFRVNCNTKGVLPGKFYEISIP
                     KYGESPISVSGYGEDYIDFTIRNVGKVTSELFNYKEGDSFFIRGPYGNGFDVSLYEGR
                     EIVVVAGGSALAPVRGIVEYFYNNKEKCEKFKLIVGFKSPKDILFADDLKRWSKKLDI
                     LVTVDGAEEGYSGNVGLVTKYIPELDMKDINNTSIVVVGPPMMMKFTVEEFLKRDLDE
                     KNIWVSYERKMCCGIGKCGHCKMDDTYICLDGPVFDYSYAKNLID"
     gene            23095..24066
                     /gene="asrC"
                     /locus_tag="PC466_002183"
     CDS             23095..24066
                     /gene="asrC"
                     /locus_tag="PC466_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite reductase subunit C"
                     /protein_id="HDF2769565.1"
                     /translation="MIRDLNTKKVMKNAYRITKTKYETSLRVRVPGGLIDPESLAVVS
                     KIASEYGNGQVHITTRQGFEILGINMEDMEEINKIIQPVIEKMNINQSEKNAGYPAAG
                     TRNIAACIGNKVCPKAQYNTTEFAKRIEKAIFPNDLHFKVALTGCPNDCIKARMNDFG
                     IIGMALPIYEKDRCVNCGACVKKCSKISVGALKTENNKVVRDKDKCIGCGECVLNCPT
                     NAWTRDEKKYYRLAIMGRTGKKNPRLAEDFLLWVDEDSIIKIILNTYRYVEKYIDKDA
                     PGGKEHIGYIIDRTGFMEFKKWALEGVELPEITKMYENIYWSGIKYL"
     gene            24123..24899
                     /locus_tag="PC466_002184"
     CDS             24123..24899
                     /locus_tag="PC466_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HDF2769566.1"
                     /translation="MHKETLDKLTNAAINKINLLNTSKVKYLVSSAFAGLYVGIGILL
                     IFTIGGLLTDAGSPMTKIVMGLSFAIALSLVIMTGTELFTGNNMVMSAGMLNKGVSIK
                     DTSKIWAYSWVGNLIGALVLGLIFVGTGLVDKGPVAEFFANTAASKASMPFTALFFRG
                     ILCNILVCVSVLCSFRTNSDTAKIIMIFLCLFAFITSGFEHSVANMTIYSVSLFSPTI
                     STVTIGGAIYNLVAVTLGNIVGGALFMGLGTYILGKEKLN"
     gene            25170..27188
                     /locus_tag="PC466_002185"
     CDS             25170..27188
                     /locus_tag="PC466_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HDF2769567.1"
                     /translation="MTKKLVISKTKLFIFIIAFISIFIYLFGSKNTLIGVGIVTAMLT
                     LLERDLTISPIKNLLKYLAINIILGILSFFAVQNMYLGVLLNFIALFIIGYVFSYDLK
                     RAVYVPFGLMYIFMVSIPVGKSEFPMRLSALAVGAVIIMIAQFVMNRNRMKNVGDKEL
                     ISICDELLEKISLLKNTINDDSSIIKSSMRKIDSCNYRINSISKNLKMVIFDNRKDDF
                     YISIRGIDIMNILFSLERISLIMERYKKDSKEFEDEDIKNILEESSINSKSDVLVVAT
                     KEINYIKMCLENKDTITDKEILGFRDYVIAQDTKNINLKEIYSVLENLYEFLVDYKKV
                     KSRDEKKAERKSKIPHEFKRLSIYKKNFNLNSIRFSYAVKIALATAVAGFIMDYFHLR
                     DGRWIMLTVFSLTQPYAENCIQRSRKRIEGTFIGAVIFIVLFSIIKDSTLRSLIVLLA
                     GYINSYVVDYRKLMVCVTVSALGSAVVMGDPNVLTISRISYVALGAIIALIVNKFILP
                     YDAKTGYQHVIEMYKGIVKNIIDEVNKSIENVADVYYIKNLLLIPSLIEDRLMLINAI
                     YKDKHQEDFLENQKLLISNMYNLYINVNKNKIKDEDVEKILRDTNYISNYNVDKYDEG
                     RSVILESIVNTKSLGDKIICLNLLQTLNGVKEMYRISNITKVSIKEAA"
     gene            27403..28260
                     /locus_tag="PC466_002186"
     CDS             27403..28260
                     /locus_tag="PC466_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF2769568.1"
                     /translation="MSKDVKVKRNKKYDTFSITMELERPLLYDEVENKDDKNNNRKFN
                     IKNKIFKGIGILFVLILLGFFIWINKTYEPQKLAKEALVSNSKVEVTVNENISFTPKG
                     RKVSKGLILYPGAKVEIESYAPLARKIAESGYEVVIVKMPLNLAILGTNKAQKVMDSY
                     NNIEHWVIGGHSLGGVAASNFARDNKLIEGVVFLASYPMGDELKELGKKVISIWGSKD
                     GVVNFKSLVESKQKLPDDTTYVEIEGGNHAQFGDYGKQKGDNDAIISQEKQLNITANS
                     IIKFLKNIS"
     gene            28357..29226
                     /locus_tag="PC466_002187"
     CDS             28357..29226
                     /locus_tag="PC466_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HDF2769569.1"
                     /translation="MEYDMPLYRPPSEAYSLIIQVTLGCSHNKCTFCSMYKSKKFKIK
                     PLEVIKNEIDIFRRYYKHVERIFLADGDALIIPMEKLRDIILYIKEVFPECERITMYG
                     SPKSIEKKSDDELKELRKLGVKMIYLGLESGSNEVLEDIKKGFSSEQLIKVGRKVKKS
                     GIKLSATVIAGLGGTKKTHQHAVDTGKMLGAISPDYVGVLSLMVEPNTELYDLLKAGE
                     FTILEDKAVLQEIKEMIKNIDANEKIVFRSNHASNYANLKGVLPDDKQRLIDEIDYYL
                     SNQKLKREEYRRL"
BASE COUNT        11697 a         2986 c         5272 g         9530 t
ORIGIN      
        1 ttgtattatt atttttatat caaaaatagt aataaagtct atatacattt agaaaatact
       61 gtttaaaagg agtaggattt atgataaaaa aagagatatc taactttaga ggaagtagtg
      121 attatgtagt atcaccagaa ttgatggcat cagttaatgt tgctattgct cttgaaaagc
      181 cacttttgat taagggcgaa cctggaacag gtaaaactat gctagcacaa gcaatttcaa
      241 atgaattaaa aaaagattta gtaatttgga atataaaatc aactacaaaa gcacaagaag
      301 ggctttatgt atatgatact gttcaaagac tttatgatag ccaatttgga ggagaaggtg
      361 tagatgatat tagcaagtac ataaaatatg gtaaactagg agaggccttt agctcaaatc
      421 aacaagtaat tcttttaata gatgaaatag ataaggcgga tttagaattt ccaaatgact
      481 tgctttggga attggataaa atggagtttt acataaatga gacaaaagaa actgtaagag
      541 ctaaacaaag accaatagtt attataactt caaatgcgga aaaagaactt ccagatgctt
      601 ttttaagaag atgtatattt cattatatag aatttcctga tagagacatg atggaagaaa
      661 tagttaaagt acattttgat aaagtagaag aacacctatt ggaacaagta atgactactt
      721 tttattggat tagaagttta aaggacatac aaaaaaagcc tagtacatca gagttaatag
      781 actggataca agcattaact ttgagtggaa tgcctattga aaaaatagaa aaagaagttc
      841 cttttgcagg aatactactt aagaataatg aggatattga atctatgcaa agacacttat
      901 agttaatagg agctggataa ttatgtttat tgaatttttt tatttattga ggtcaagagg
      961 attaaatata tctttaaatg aatggatgac tttaattgaa gcattggata aagggctgtg
     1021 ctattcaaac ttttcaaatt tttactatct ttgcaggatg attttaataa aaagtgaaag
     1081 tgattttgat aagtttgatg cagtgttttt ggagtatttt aaaggtatag aacaccaaga
     1141 agaaattcca gaagagatta tgaattggct taaaaaacca gatatagatt tagaagagtt
     1201 tgaaagattg gaacaaaatc caaatataaa tcttgataaa ttaagagcta aattggagga
     1261 acgaataaaa gaacaagact ctcctcataa tggtggtaat tattggatag gcacaggagg
     1321 cacttccgag ttaggacatt caggaaaagg gcaaactggt atacgtatag gtggaaattc
     1381 tacttatggt agagctgttc ttgaagttgc aggagaaaga aaatacagag attttagaga
     1441 tgatgaagtt ttaaatatgc gtcaatttca agttgcacta aagagacttc gtcaattttc
     1501 tactagaata gatgctccaa agacagagct tgatttggat aagactattg aagagacttg
     1561 taataatgca ggatatttaa agttattttt tgagaagcca agaaaaaata cagtgaagct
     1621 tttattgctt atggattcag gtggttcaat gagggggtat agcactttat gtaatacatt
     1681 atttcagtct gtaagtaaat caaatcattt taaagatgta aagatatatt atttccataa
     1741 ctgtatttat gatagattat ttacaacacc tgaatgttgg ttaagtaaat ctattaatac
     1801 tgaatggata ttaaaaaata tagataaaaa ctataaagtt ataattgttg gagatgcttc
     1861 tatgtcgcct tctgagttac ttcatattgg tggtaactat cgtggtccat ataattacac
     1921 acctggtata gaatggctta aaaggtttaa gagaaagtac agtaaaattg tatggatgaa
     1981 tccagaactt agagatggat gggattcaat taattattgg taccaaactc aaagaatgat
     2041 acaaagtgaa tttaatatgt ttccactgac tgtaaaaggt cttgaaaaag cattgaaaaa
     2101 tttaatgctt tcaagataaa gtaaatataa atgatggtat gatttattca aaattgtacc
     2161 atcattattt attttttaat atatctatta taaattgtat aactgaaact taaaaaatta
     2221 tatagtctaa tacattttag acttacacaa aacatataca ttaataataa ttttagaagt
     2281 cgaggtgatt ataataaatt atgaattaat tgtaaaatac aatggagata tattgagatt
     2341 agaagaagaa ttaggtgtat cagtagagat acttaattca tcatatgcaa taataacatc
     2401 aagtaatgaa gaagatgtaa atacactttt aacttatcca gaaattgaat ttatagaaaa
     2461 gccttttata ttacagactc aggatgtgca aagtttttca agtacaggaa taacggggtt
     2521 taaaaataga actggtttaa ctggaaaggg aactataatt ggtataattg attcgggaat
     2581 agattatact ctacctgtgt ttagagatag tgatgggagg tctaagatat tatattattg
     2641 ggaccaatct attcaaggaa atccaccaga aggttttaga gaaggaacat tatatactaa
     2701 tgaagatata aataatgcaa tagatggaag tatgtatata cctatttcaa caactagttt
     2761 acatgggaca catgttgcag gtatttgtgc aactattgca agtgatgcca gaataatagt
     2821 ggttagagtt ggaaatatac agaccgatat tttttcgaga agtacagagt ttatgagggc
     2881 aattaaattt attttagata gggcattaga attaagaatg cctgttacat taaatataag
     2941 ttatggaagt aatgaaggtt cacatagagg aacatcttta tttgaacaat atatagatga
     3001 tatgtgttta ttttggaaaa acaatatagt tgtagcagct ggaaataatg cagataaagg
     3061 aggtcataaa aggattaggc ttcaaaataa tattacagaa gaagttgagt ttatagttgg
     3121 ggaaggagag cgtatattaa acataaatat atggccagat tttgttgatg attttagtgt
     3181 acatttggta aacccatcaa acaatcaaac acaagcaatc tctctaactt caggtgagat
     3241 aagaaatact ttgggtgaaa ctagaataac tggttatttt taccctatag caccgtactc
     3301 tcttacaaga agagttactc tacaattaag ttcaaataca cagataactc ctgggttatg
     3361 gaaaattgta tttgaaccaa tagatatagt aactggtaat gtaaatatat atttgccaac
     3421 ttctgaagga ctaaatagaa atactagatt tctgattcct actcaagagc ttactgtaac
     3481 agttcctgga acagcaagta gagttgtaac agtaggtagt tttaattcaa gaacagacat
     3541 agtatctata ttttctggtg aaggagatac acaattaggt gtttttaaac ctgatttatt
     3601 agctccaggt gaagatataa tatctttttt accaggaggt acaagtggag cattaactgg
     3661 aactagcatg gctacacctc atgttacagg ggtttgttca ttgtttatgg aatggggaat
     3721 tgtaaatgga aatgatttat ttttgtattc acagaaatta agggcattac ttttaaaggg
     3781 agcaaggaga ttaagtaatc aatcttatcc aaataattca tcaggatttg gttttttaaa
     3841 tttatcagat atagatttgt acactctatc tagtataaat caagatttag aaacggagga
     3901 tattggatat agaagtatta ataagtcatt taaagatgag gaaaataggt ataagtttat
     3961 agatggttat aatatacaaa tacataatga cttagagaat gaaatttata taagtaaaaa
     4021 tgcaagtaga caatcaggaa tactatcagg aatagatgta gtccatactc ccgaatttga
     4081 agaagaacta gctgggttag gtatgagtca aaattttttt aagataagtg attcattagg
     4141 tgtactatct ataaataata cagactatag tagtatacaa cgagttttgc aacttccttc
     4201 aatcataaga actgtatcga ctacaaagat gacattactt ggagaaatta atcgaggtac
     4261 ttttggaggt gtagttgcaa cagaagaaat gggcgtaaat ttctttaaaa ataatcctaa
     4321 tattaatata acaggaagag ggactctaat atcaattgca gatacaggaa tagactatct
     4381 acatccagat tttatttatc cagatggtac ttcaaaaata gtatatttat gggaccaaac
     4441 aaaagaagga actccacctg atggttttta tattgggaca gaatatacac gagaagatat
     4501 aaatcgagct atcgcagaaa atgaccctag tctatctcag gatgaagttg gtcaaggaac
     4561 tatgttgagt ggtatatgct cagggcttgg aaatgtaaat agtgaatatg caggtatagc
     4621 agaagattct gagctaataa taataaaact cggtaagata gatggttttt ataatagtgc
     4681 aatgttgttt gctgcatctc agtatgcata taaaaaagct tttgaactta gaagaccact
     4741 agttataaat atgtctttag gtaccagtag cttggcaggt ttaaccaata ggagcaatag
     4801 tgaaaaagca ttctttacta gagggttatg tataacagca ggagcaggaa atgagggcaa
     4861 tacacagaca catacatctg gaataatacc acatgttgga ggttctgttg aagttgaatt
     4921 agagttaaat gaagacgagg aagaattatc attagaactt tggttaaata gaccagataa
     4981 agctgatgta ataatagtat ctcccactgg tgaagaaagt aaaagtgttg gaatttcaaa
     5041 ttataataaa gtaacaggtt tatttgattt agaggggact gaatattcta taacgtatat
     5101 atacccaaca actttttctg ggcagcaatt tactaatgtt actttaaaga atgcaaaaag
     5161 aggtgtatgg aagattcgat tagtaggggt ttatattata acaggaagat ataacttata
     5221 ccttccaaat agagaacttt taaaaagtgg aactagattt agagaggtag acccttttta
     5281 cactataaat tatcctgcta ttcaagatga tttaataact gtaggagcct acaatactat
     5341 taatggtagt ttatggcaaa gttcatcaag aggaccaact attgaagaca ggttaaaacc
     5401 agatatagta gcaccaggtg tcaatataat agctgcttat cctgggaaca cgtatgcaac
     5461 tataactggt acagcagcag caagtgcaca tgcagctggt gctgctgcaa tgtatttcca
     5521 atatactttt gttgatggta gatatccaaa ccaagcatat gtgcaaaaaa taaaaacttt
     5581 tatgcaagct ggtgctagaa aagattcaaa cacagtatat ccaaatacaa attctggata
     5641 tgggcttttg gatgttagag gaatgtttga tgttttaaga taggagggat ttatggaaaa
     5701 atcttattgt ataatttatc aaggtgatat agaatctgcc ctacaagaaa atggaataaa
     5761 taggtatatg gttttaaata gtcagcttgc agtaatatat gtacctgtag attttgatga
     5821 aactatttta aataatataa tacaagttgc ttggtgggaa gaatctgaac caatgagcag
     5881 tctaattgaa ataactaata atgtaaataa tggagaaacc attacaacag cagctgaaac
     5941 tgattatatt tatgaaaatc catataatga tataacagga agaggaattt tattagcagt
     6001 tatagattct ggtatagatt atttgcatcc tgattttata aatgatgatg gaactagtaa
     6061 agttctatat ttatgggacc aagaagcaaa tacaaatcca cctccagaag gttttatttt
     6121 tggaagtgaa tttacaagaa gtcagttaaa tatagccata aatagaaatg atggaagttt
     6181 gagtcaagat aatataggta ctggaacttt agtttctggt atattagctg gaaatggaag
     6241 gataaattcg cagtatagag gtattactac agaatcagac ttaatagtag ttaaattaaa
     6301 atcatataca gatacttatt atgctggaag gataaattat agtgtttcag attttttagc
     6361 agctataacg tatgttacta atatagcaag aacagaaaat aaaccactaa taataaattt
     6421 gactattgga gttaagtcaa gtgctgtagc aactacttca atattagata cttttaatat
     6481 attgagtagt gctggtgtgg tagtagtgag tggtgcagga aatcaaggga atacagatat
     6541 tcattattct ggcagattta gcagtgtggg agaagttcaa gatgtaataa tacaagatgg
     6601 agatgactat gctcttgata taacactaaa tacgaatggt ccagataaag tgggagcaca
     6661 gataatatct ccttcaggtg aagttagtca tgatataagg tattctccag acttttatat
     6721 atatagagga aaatttaact tagaaaatac tacttatgca atgagattta tttatccata
     6781 tattacctct ggaaaagaaa atttggagat aagattaaga gatataaaac ctggagtatg
     6841 gattttaaga ttgacttcag aacttataat aagtggagaa tatgacatat acttaccaaa
     6901 taaaaatttg atagctccag acacaaggtt tttagaccct gattcagtag ctactataac
     6961 tatgtatgct gctagtgatg atgtaattac agttggtaca tttaataata agactgatag
     7021 tatgtggatt ggttcttcga aaggaccaat tagaggaaga ggaattaagc cagatatagt
     7081 agcttcaggt gtagatataa tatccacata taaaaatgga acatataata caggaacagg
     7141 aacaggagtg agcagttcta tagtcacagg tgttttagcc ttattgatgg aatacttaga
     7201 aaaacaggat aatgtaccga gattatcatt gtttacacaa gttttaaaaa catatttaat
     7261 attgggtgct acaaaacttg agatatatac atatccaaat gtatcgcagg gatatgggat
     7321 tttaaattta aaaaatacga ttcaacagat agcaaatact ctatagataa gaacctatgt
     7381 aaaattataa ttgattagta atttaattgt atcaaatact ttagatagag tagaaaaatg
     7441 gcataaaaaa taaatatgaa aattaaaaaa acagttttat attttgaata cacaaagtaa
     7501 atattttgta tataaatagg tataaattaa gtattgaaaa gatatgatgt taatttaaaa
     7561 atcattataa tttagactta tgaattttat ttgtaaaatt gctaaaacta ttacaaaata
     7621 aataatagag gtgatagttt tggaaagtaa aaaggcaaga gcattaaaag gtaaagataa
     7681 taaaagactt aaaagttcac ttttagttgg aaatgagtcg acagcagcat gggctgatgt
     7741 tgaaaaatta aaacctcata gtaaagtttc aataccttca attaagggtg tcgaagaagc
     7801 aaaagactgg gttgacaatg gaagtaaatt ataaaatttt ggaaatttaa gtaataaaga
     7861 agtaatgaag ataagtattt attatcatta tgcaaggtag aattattata ttttaaataa
     7921 caatcagtat caattatata aatttattga ctaaaaattt ataaattggt ataattttgt
     7981 taattagtag aaataataaa agataaatac tgtgaagaga agagtagata taaaatgtag
     8041 ttctagcgag ttgaggatgg tgaaagctca atacgaggtt tatattgaag aacatcttgg
     8101 agtttctaat cgaaagctta tttagtaagt agacttagac ggaaggcacc gttataggct
     8161 ttaagcattg cttaactaag aggtcattat gacaactagg gtggtaccgc gagagtaata
     8221 gtctttcgtc cctttatata gggatgaagg gcttttttta ttgaaattat atttaaaaga
     8281 aattaataac aattatacta ggaggattta aaatgcaaaa ggaatttata acagtaaaag
     8341 aattgtacag agaaaaagaa cagtacatag ggaagactgt aaaagtagct ggatggataa
     8401 gaacatctag agtatctaaa aattttggat ttatagagct aaatgatgga agcttcttta
     8461 aaaatatgca gatagtattt gatgagaaag tagaaaattt taaagaggta ggaaaattag
     8521 caataagctc atctatactt gtagagggag agttagtatc tacagaaggg gctaaacaac
     8581 cagtcgaaat acatgcaaaa agcatagttg tagaagggga atcagatagt tcgtatccac
     8641 tacaaaagaa gagacatacg cttgaatatt taagaacgat agcacattta agaccaagaa
     8701 gtaatacttt ttcagctgta tttagagtaa gatcaatagc tgcctatgca atacacaaat
     8761 tcttccaaga aagaaacttt gtatatgcac attctccaat cataacgggt agtgactgtg
     8821 aaggtgcagg agaaatgttt agaataacaa ctatggattt aaatgatatt ccaaaaactg
     8881 aagatggtaa aatagactat actcaagatt tctttggaaa agaggctaat ttaacagtta
     8941 gtggtcaact aaatgccgag ataatggcac tttcttttag aaacgtttat acttttggac
     9001 ctacatttag agctgaaaac tcttatacag gaagacatgc ttcagaattt tggatgatag
     9061 agccagaaat agtttttgca gaccttgaag ataacatgga acttgcagaa gatatgataa
     9121 aatatgttat aagctatgta ttagaaaatg ctcctgaaga aatggaattt tttaatagtt
     9181 ttatagataa aggattgtta gaaagattaa ataagatagt aaactctgag tttattagaa
     9241 taacgtatac taaagcagtg gaattattaa ttgaatctgg tcatgaattt gagtatcctg
     9301 ttgagtgggg atgtgacctt caaactgagc atgaaagata tataacggag caaatatata
     9361 attgtccagt gtttgttaca gattatccaa aagatataaa agctttctat atgagaatga
     9421 atgaagacgg taaaactgtt agagcaatgg atttattagt tcctggagtt ggagaaatcg
     9481 taggaggttc tcaaagagaa gaaagagaag atgtattgtt agatagaatt aatgaaatgg
     9541 gattaagaga agaagattat tggtggtatt tagaacttag aaagtttggt actgctactc
     9601 actctggatt tggtcttgga tttgaaagaa taattatgta tatgacaggt atgtctaaca
     9661 taagagacgt tatacctttc ccaagaactc ctaaaaatgc tgaattttaa taattatata
     9721 taataaaact tatataactt taagtataaa cactaaaatg acttgcatat ttatctattt
     9781 tagagatatg caagttattt ttattgtact ataaatatat aatttgatta cttttatttt
     9841 gcgatataat acttataggt ttatataata gtatgtaact ttttaataaa atgcaacaca
     9901 attacgtccc tgttcttttg cagtatatag agccttatca caattactta taaactcatt
     9961 taatgttatt gccttttcaa ttttctttgt ataaactcca atactaacag ttacacattt
    10021 taaaggaaca tcatcacgct caaaattgca ggactctata atttttcgta aacattctga
    10081 tttaagttta gcatctgtct catcacagtt aaaaatacat ataaaaaatt cctcaccacc
    10141 atatcgtata gcatgttcat tttcagaact tgtaaaatct aaaattactt tggcaatatt
    10201 ttgtagacaa tagtctccct tttgatgtcc ataattatca ttaaattgtt tgaaataatc
    10261 tatatctatc atcattccag ttataggttc ttgatttgca tggctgatta attttttttg
    10321 tagaatatct tcaaggtatc tacggttgtt cattttagta aggtcgtctg tcataacttt
    10381 gtcgttaagt aaattattta tatgagatat ttcttcatat tgttgactaa ttaaaagttt
    10441 atcatagtaa gtaaatacac gatttctata tagcattgta gaaacaaaaa tggcaaggga
    10501 tgttataaaa aatgtgttga caatattact aaactcattg cctggtatag tttgaatccc
    10561 aggtaagaat aaattaagaa acaaaaagca tcctccaaaa actattactg attctccaaa
    10621 ttttaatact gagaaagctg cagctgctaa cataatataa ctaaatacac ttaggtcatt
    10681 tccacctaac tggtcaagta gagtaattac acaaccccat aggcagaaaa aagtcacata
    10741 aattatccat aaatttatat aaaacgtaca acaatccttt tttttattcc aaagataaga
    10801 aaatacaaac ataaagacag aagatacaca aaatagtgtt acatacatat aaaaatacca
    10861 ttggcgtctt ggtgtggcaa aagggcctcc ttctctagct gagattgata tcatcataat
    10921 tatttgagat attactatta ttatgcaaat gattttaccc gtatgataaa gataattgca
    10981 gagttctttt tcaacatttt ctttgtgttt tttgtctaga ggaaatccaa aaaatttttt
    11041 tattttttct aagttcatat aagcctccat taaaaataaa gcataaaaat aagtattcct
    11101 ttctatcatt agatatttgg aatacttcgt ttatgattta attatatcaa aatatattgt
    11161 gtgtaacaat ctaaaattgt gatagataaa atttattagc taatgttgag taactttatt
    11221 aattaatact ttactataat taagatttac agatagtttg ctgctgaaaa taaagaatag
    11281 aataaattta aattaagcat aataaaatat aaataataaa gttcgcatta acaaactatt
    11341 taaatatcaa gacctgttaa aaaacaacag caataaacaa ataaaataga taaatatatc
    11401 caattaaggt ataattaagt tttatatgat atagttatat ttgataattt acaatagtaa
    11461 aacttggagg gaaaaaatgg gtgaaaagaa aataaataat atgaattatt cacataataa
    11521 ttattccaaa aagacaggtg aaccaactag aaaaataaaa aatagccata tcactcttaa
    11581 aagtaaagaa gaaaaaattt gttctagttg caataaagaa aataatacta aggataatta
    11641 ctgtaaattt tgtggaaatg aactttatga aatagcatca ttaagaccac ttgaaacaaa
    11701 actagacttg aaatctaaaa taaaagagct ttcatatcat gcaaataaaa gaggtgtatt
    11761 tttaacaaca tttacaacca tatttatatt gtttattatt gcattgatat ttaaagctat
    11821 tataactatt caatttaatg atattagtta tttaataaat ccagcacata taatcctagc
    11881 tctcaacttg ggtcaaatta gtgtatctat gtctaccatg atgggttctg ggtttataaa
    11941 tgccaatata ggtttgttga tattacttat aatccctatt ttggtattat taatatcaaa
    12001 cctaattttt atgagaaaaa gatgtagaga ttcaaaaact gtattagcaa attctctagg
    12061 agttggaatt ttttatggat tagttttagc tattttatct atttttacta atgtaaaaac
    12121 tagttcacat agtatgttag aatatggata tgcattagaa tatagttatg aattttttag
    12181 tgttctttta aatggatttg tattagggtt tatatgtaca tacataacta cttataaaaa
    12241 aagttatgaa aaggaaaata tgtatttatc tcttttttca aattctataa gaacattcat
    12301 attaggttat gttttagtat tagtaatact attggtacta actatatctg atagtagtta
    12361 cttaaatgaa ctagatatga gtagttattc aaatggatta aatttattta ctatactccc
    12421 acaaatagct agttatatgt gggcttttgc aaatggaatt tcagtaacca taataaactc
    12481 aacagtatca atgtttactt taagttcttc atctttattt ggagatacta aattaatgtt
    12541 ttatgcaatg ggagcattgt ctatgttaat attattatta aatggataca agctaagatt
    12601 taagtataat acagatagta taagacctat aatagtattt agtatatatt atgcattttt
    12661 gatgggaata ttggctttat ttagtacatt tatactagat agtaatatta atttctttaa
    12721 tacaactaat tatggaacaa ctttaataat gcaatttaaa gtcttacaag ctattgtaat
    12781 ttcatttgta tatagttttg tgatatcttt aataggatat aagctaaatt cagctgatta
    12841 aatatgattg gagggaattt ctgtggaagg aaatactaat aataaagtag atgataaatt
    12901 ttctaaggtt aagaaaaagt ttggtagtgg aaaatttaaa gttgaattat ataaagaaaa
    12961 atcaaaatta aatagagaga ttgatgatat tcaagaaaag aaagcaaaga tattcttgga
    13021 aatgggaata ctgacatatc aaaaaattag agaagattct attaatgata atagttttga
    13081 taaattctgt gatgagttac tagaacttga taagttaatt tatgaaaaaa atatggaaat
    13141 taatgaaatg gaaatggcag aaagtaatgt aacttgtgag tgtggttatg ttggaaatgt
    13201 aaatgataaa tattgtgctg aatgtggtaa aaaatttgaa ttggaaaatg aatgtgatga
    13261 ttttataatt tgtggttatt gtgaaagtga gatagataca gaggctgaat tttgtccatg
    13321 ctgtggaaga aaaattataa tggatttaga ataatattgg gaaacctatg tatagtatac
    13381 atgggttttt ttattgaaat tatttaaatg gacttataac agtagttata taaaatgaaa
    13441 ataaacacca aaaaaatgaa ataaaatttc ttttaaatgt aaaaaacaag ctaatatata
    13501 aaataaatca gtaaaaatat agatgcgaga aaaaaatatg aaaaaatatt gcaaagaaaa
    13561 agttttcatg ttattattaa tacataaatc aagaaaataa atttcagaaa cgaggtaatt
    13621 taaaaaatgc tagataaggt aaagggaaga ttaatagtat catgccaagc tttagaaaat
    13681 gaacctcttc atagtccttt tataatgggg agaatggcta aggctgctat ggaaggtgga
    13741 gctgttggaa ttagagctca aggagttgaa gatattattg aaataaaaaa agttactgga
    13801 cttcctgtta taggtattat aaagagaaac tatgaagatt cagatatata tataacgcca
    13861 actaaaaaag aagttgatga acttttaaca acagggtgtg aaatgatagc attagatgct
    13921 accaatagag ttagaccaaa taatgaagac ttaaaagaac ttataaagta tataaaagaa
    13981 aacggtgttc tagtaatggc agacatttca aattatgatg aggctatcaa agcacaagag
    14041 tacggtgtag attgcgtttc aactacacta tctggatata ctccatatac taaaacatta
    14101 gaaggtccag attttgtatt aatggaaaga ttagttaaag atttagaaat acctgtaata
    14161 gctgaaggaa aggtaaatac tcctcaagat ttaaaaaagg tctttgagtt gggtgttcat
    14221 tcatcagtag taggttcagc aataacaaga ccacaattaa taacagaaaa atttgttaaa
    14281 gcaattgaaa ttaattaaaa attaatttat aaattaaaaa attattatat ttaactatac
    14341 ttgaaaatta aaattggagg taaagatatg agaacaacag atatgaaggg aatttattca
    14401 gcattattag tttcatttga taaggaaggg aatataaatg aaaaagggtt aagacaaata
    14461 attagacaca atatagatgt ttgtaaagta gatggtcttt atgtaggagg aagtacaggg
    14521 gaaaacttca tgctttcaac tgatgaaaag aaaagaatat ttgaaatagc taaagatgaa
    14581 gtgaaagaag aaataaaatt aatagctcaa gttggttcag ttaatttaaa agaagctgta
    14641 gaacttgcta aatttacaac tgatttagga tatgatgcaa taagtgctgt tacacctttt
    14701 tactataaat ttgattttga agaaataaaa cactattata atacaataat aaattctgta
    14761 gataatagat taataatata ctctatacca tttttaactg gtgttgatat gagtttagac
    14821 cagtttggag aattatttga aaatgaaaaa ataataggtg ttaagtttac agcagcagat
    14881 ttctacttat tagagagaat gagaaaaaca ttcccaaata aattaatatt tgcaggattt
    14941 gatgaaatga tgttaccagc tacagtttta ggtgtagatg gggcaattgg ttctacattc
    15001 aatgtaaacg gtgtcagagc tagacaaata ttcgaattaa ctaagaatga aaaaatatca
    15061 gaagcacttg aagtacaaca tgtgactaat gatttaataa cagatatatt aggaaatggc
    15121 ttatatcaaa caattaaatt actacttgaa gaacaaggtg ttgaggctgg atactgtaga
    15181 caacctatga aagaagcaac tgatgaaatg aaatcaagag caaaagaaat atacagaaag
    15241 tatttttaat aaaatacttt tagtatggga ggattagtca aatggtagga tttacttgga
    15301 tagattttgc aatactagtg gtttacttat tggcagtttt atttgcagga ttgttatttt
    15361 caaaaaagga aatgaaggga aaagagttct tcaaaggtga tggaactatt ccgtggtggg
    15421 ttacatcagt atcaatattt gccacattat taagtccaat atcattttta tcattagcag
    15481 gaaattctta tggtggtact tggattttgt ggtttgcaca attaggtatg tttatagcaa
    15541 tacctttgac aataaaattt ttcttacctc tgtatagtag gttagaaata gatacagcat
    15601 atgaatactt agaaatgaga tacgaaagta aaggtcttag agtacttgga gctttgatgt
    15661 ttataatata tcaaatagga cgtatgtcta tcataatgta tcttccatca gtggttctag
    15721 ctggtcttac aggaatacct gtaaatgtat tgatagtagt tatgggtgta atagcaataa
    15781 tttattcata tacaggtgga ttaaaggctg tcttgtggac agattttata caaggtatgg
    15841 tattaatagt aggtgttaca gggacattgt tctatttaat agcaagtata aatggtggtt
    15901 ttggaacagt aatggatact cttacaactg gacacaagtt cttagcaagt aatgaagtta
    15961 tgtttgataa aaatatacta tctacaagtg catttataat atttattgga gctggtctta
    16021 atactttttc atcatatgta tcgagtcaag atatagttca aagatttact acaacaactg
    16081 atataaagca acttaataaa atgacatatg gaaatggtgt tttatcaatg ggacttgcaa
    16141 cagtatttta tctaattgga acttgtttat ttatatacta tactcaaaac ccagatttag
    16201 ctcaaacagt tcaacaagac caagtatttg catcatatat agcttatgaa ttaccagtgg
    16261 gtataacagg aatactactt gcagcgatat atgcagcttc tcaatcaact ttatcgacag
    16321 ggcttaattc agttgctaca agttggactt tagatataca aactatcata acaaaagata
    16381 taagtatgga aaagcaaact aagatagcac aatatatatc attaggtgta ggtatacttt
    16441 ctatagctgt tgcaatagta ttagcaaatg gagaaataaa gtcagcatat gaatggttta
    16501 atagttttat ggggctagta ctaggtgttt tagcaggaat atttgtactt ggtgcatttt
    16561 gtaaaaaagc gactaaaatg ggagcatatg ttggattcat agtatcagca attttagttg
    16621 tttatttaaa ataccgtatg ccagaagtaa cttcttgggc atattctcta ataacaatca
    16681 cgacttctgt agtggtaggt acaatagtta gtgcaataga agctaaagtt aaagcaaaag
    16741 tatctttacc aaaagctgag actactgttt attatgaaaa ataatattta aatgataaat
    16801 tgtcttatag agtgattaga taaataattt agttactcta taagattgta taatatactt
    16861 tgtatataaa agtataaaaa tagactttat aattatatag ggagatagtg cttatgatat
    16921 ttggaaatat aaatcatagt aagacatatt caacattgca tgaagattta cttagatgtt
    16981 ttgaatatgc taaagataat tcattaatag attatgaaaa aggtacttat acaatagatg
    17041 gtgatgatat ttttgtgaat attgtagagt ataaaacttg tgaaaaagaa gatagattct
    17101 gggaagctca taagaagtat atagatgttc atttgatgct tgatggatgt gaacgaatag
    17161 atataaattt tatagaaaat ttagaacaaa aaatatatga agaaaagggc gatttcttgc
    17221 ctcttgatgg taaaaataat ggatacatgg aacttagaaa aggtgatttt ttagtttgtt
    17281 atccagaaga tgctcatatg acaggaataa aagttttaga aaaagaaaat atcaaaaaag
    17341 ctatttttaa ggttttggtt agataatgat aatttatata accactaggg ctgaaaatag
    17401 tgatttaact ttcagcgatt agtgagactt cgtaaatttt agttagatta ctattttcag
    17461 ccttagtttt ttatgagaaa attgaaaata attaaaagct taaaattttg taaaggagtt
    17521 aacttatgga aaatatagat gtattcttat taataggaca aagcaatgct agaggattgg
    17581 gaaatccaaa agagagcatc attccaaatg aaaattgttt tgaatatttg agtactgatg
    17641 aaattataaa tatgagatgt gagctagaga cttcagaagg tgatggtact atagcacctg
    17701 cattttcaaa tgaatggaat aagcttactg gaaataaagt ttgttttatt cacaatgcaa
    17761 aagatggttc aagaataaaa aactggaatc atgataataa ctggtttcta aatgacacta
    17821 tagaaaaatt taatacaggc tgtactacct taagtaaaca ttataatata gaaaataaat
    17881 acgttatttg gattcaaggt gaaagtgatg caaaatatgg tagtgatgca ttgtactata
    17941 aagaaagtct aaaaaaaatt gcgtataggc ttaaagaaga atgtatgatt gataaaatgt
    18001 ttgtaagttt aactggttat tggcttggag aagatgaata ttttattaga acaagacgaa
    18061 ttgcagcagc tcaagaatct gcttgtaatg aatgtgatat actgtgtgta ggaagtaaaa
    18121 ttgctatgca atttcatgac agaggattaa ctattgatga tgttcattac actcaagaag
    18181 gtcttaatat gttaggagag gacttatgta aaaatattta taagtatcat ataaccaaag
    18241 aaaaaagtgt attaagtgat actatagact tatcagaagc aaggaaatat atctgtgaat
    18301 tggaaaagat aagtaaaaga tttgtgtaat ataaaatttt aaatagagtt gttaatttat
    18361 aaaaataatt tgtatggaga tatgttatga aaaattacgt ttgtatagat gttggaggta
    18421 cttcaataaa atatggtttt attagagaag atggatttat aattgataaa tcaagtcttg
    18481 atactgaagc aaaggaaaaa ggtggagaag gaatattagc caaaataaaa gatatagtaa
    18541 aaaaatatat agaggaaaat gaaataagtg gtatatgtat atcaactgca ggtatggttg
    18601 acccagttga aggtaaaata ctatttgcat tagaagaatt aattccaaat tataagggta
    18661 tgcaattaaa aaaagaagta gaaaaagagt ttaatataaa atgtgaagtt gaaaatgatg
    18721 ttaattgtgc tggacttggt gaagtgtggc ttggcgcagg tagaggtgca acatcttcta
    18781 tatgtttaac aataggtact ggaattggtg gatgtattat aataaacaat aaactgataa
    18841 atgggtttag taatagcgct ggtgaagtag gatatatgaa tataaatgga agttcttttc
    18901 aagaattggc atctactagc agtctaatta aaaaagtagc aaaaataaaa aatttgaatg
    18961 aaaaggactt aaatggaaaa ataatttttg atttagcaaa gaataatgat gaagattgtt
    19021 taaaagaact cgataatatg ataaaatcat tagcagttgg aatcgcaaat atatgttatg
    19081 taataaatcc agaagtggta attttaggtg gtgggattat ggcacaagaa aagttcctaa
    19141 aaccaaaaat agacaaagca ttaaaggagg ttcttataga gagagtttac aaaaacacta
    19201 atatagaatt tgcaaagaga caaaatgatg caggaatgct tggagcatta tataattttt
    19261 taaacaaaat ataaagaata gaagggtttt taatgagtat tttagaacaa ttggaatcac
    19321 caacttttaa agtcacaaaa tcagataaat tattaatagc ttatataaaa gaaaatatag
    19381 atgatgtatt ttataaacca atatcacaaa tagctaaaga gagcaatatt ggtgaagcaa
    19441 ctataactag gtttgtaaaa aaaatgaatt ttaatggatt acaggatttt aaagttactt
    19501 tagcacaaga aatatcaact atcaataaaa aaaatattat aaataaaaat atacaaaatg
    19561 atgagccagc tttggataca gcaaaaaaac ttttaagttc aaatgtaacc actttagaga
    19621 acacagtaga gataatcaat agtaaggatg tacatgactg tgcaaggctt ataataaatg
    19681 caaagaaagt ttacttcata ggcattggat attctggtat aatagcacag gattcaaact
    19741 ataaatttat gagaataggc cttaattgtg taagttttga tagcagtcat acgatgataa
    19801 tgatgtcttc cataatggaa gaaggagatt taataattgc aatttcacat tctggtgaaa
    19861 cagaagagat tataaaaact gtaaagcttg caagagccaa taatgctaaa attatatcaa
    19921 ttactgaaaa taaaaattct gaattaaagg atatttcaga tgtacactta tcttatgtat
    19981 caggagaaac agtactggaa actggttcaa tatcttctaa attagcacaa tttttcatta
    20041 ttgatttagt atatacacag gtagtaaaag aactttctaa tgaagctatt gaaaggaaaa
    20101 ttaaaactac aaatgctata aaattgttta aaaatgaata aaataagaaa tttgtaatgt
    20161 tttatagagc tctcttaaaa atttaggaat ggagagatat tacatgtcta aattaaaaga
    20221 ttataatatt gataaagtaa taatttttaa taatttaagt actaaaacga agaatcaact
    20281 taaagaaaaa gctaaactaa aaagattaca aaaaaaagaa attttatttt atgaaaaaga
    20341 tagcttagac agtgtttata tacttttaga aggaaaggta tctattttta agataagtga
    20401 aaatggagag agaaaagtaa ttttcatatt aaatagtggg gaagtcataa atgatattac
    20461 atttgactct tctaaaaact ccactgttgg ctgtgaagca tttgaaaatt caattgtagc
    20521 ttattatagt attgaagaat ttttagaaat tatgcaaaat gattttcaac ttacaaagga
    20581 tattatttct tatatggaaa gaagaataag acgtttatat agacagttga aaaattctat
    20641 atccataaaa gtagataaaa aacttgcagc aaaattatat aggttaagta gagaatttgg
    20701 agtttgctgt ggagaatgga ctttactaaa tgtaaatatt acagttacat atttagctga
    20761 tatgcttggc tgtaaaaggg agactgtttc cagaatgata aaggtattgc aaaaagaaga
    20821 acttattaag attgataata aaggttttta tgttaaagaa actgaattat caaggtattt
    20881 caaaaataat taattatgat taagtaaaag tattattaga attttaatta aataaaaata
    20941 ttattaagag aatctattta tagattcttt tttattgtct aatttattaa tttttatttt
    21001 accctattga attgtataaa aaagcaaata agattcttta ttattcaaaa aattgagtag
    21061 ataatagttt tattgtattt aatgattgta tctaagtgat tagatttgaa atcgaataat
    21121 atagataata aaaaaatatt aacagagatt agtaaactct attaatattt ttttattatt
    21181 tttgaaactg tgataattat cacagaagca tagaaaataa agtgttaaga tttaaacaag
    21241 atagcaagta agtaaaacta aaatataaga aaggtgataa aaatgaaact aaaattagat
    21301 tcatctaagt tcaatgaagg tctgaattat ctaaaaaaag actacaagat atttgcacca
    21361 gttttaatcc catttaaagg tactttttca gatactgatg ttataagata caaggaggta
    21421 aacgcttttg aagaaatgga atttgctaag aaagcaaact tttcaccaaa agaagttgta
    21481 cttcccataa atcaagtatt gttttatttt actgaaaaag agtttaagga aagcgattta
    21541 gacaacaaga aaattttaat tttcttaaga gcttgtgaca taaatggtat aaaaagactt
    21601 gatgaaatat atctaaataa tggtgaagaa aaagattatt tttataaaaa tatcagagat
    21661 aaagtaaagt ttgcacttgt agggtgtaag gaaagtttta gaaactgttt ttgtgtgagc
    21721 atggattcta acaaaactga taattattca attggattaa atatagaagg agatacactg
    21781 tacttagata taaaggatag tgaatttgaa gtatttaatg gagaagcaac tgaatttaat
    21841 gttgattatg taactgataa tttaatatct gtagatgtgc cagagaatat tgattcaaat
    21901 gaaattatag gaaattcaat atgggatgaa tatgatacaa gatgtatagg atgtggtaga
    21961 tgtaattttg tatgtccaac atgttcatgt tttacaatgc aggatatttt ctataaggaa
    22021 aacgaaaatg taggtgagag aagaagggtt tgggcttctt gtcaagtaga tggatataca
    22081 gatatagcag gtggaaattc ttttagaaaa aaacaaggtg aaagaatgag atttaaaact
    22141 atgcataaaa tacatgattt taaaaaaaga ttcggatatc atatgtgtgt tggttgtgga
    22201 agatgtgatg atgcctgtcc gcaatacata tcattttcaa agtgtataga aaaaataaat
    22261 gatttagtaa ttagtaagga ggaagtataa atgaacccat atataccagt aagtgcaaaa
    22321 atactagata tagttaaaca tactgataaa gaatggactt ttagagtaaa ctgcaataca
    22381 aaaggtgtat tgcctggaaa gttttatgag atatctatac ctaaatacgg tgaaagtcca
    22441 atatcagtat caggatatgg agaggattat attgacttta caataagaaa tgtaggaaaa
    22501 gtaactagcg agttgtttaa ttataaagaa ggagattctt tttttataag aggtccttat
    22561 ggaaatggat ttgatgtatc cctttatgaa ggaagagaaa ttgtagtagt ggcaggagga
    22621 agtgcattag cccctgtaag aggaatagtt gaatattttt ataataataa agaaaaatgc
    22681 gaaaagttta aattaatagt aggatttaaa tcaccaaaag atattttatt tgcagatgat
    22741 ttaaagagat ggagtaaaaa acttgatatt ttagttactg tagatggagc agaggaagga
    22801 tatagtggta atgtaggatt agtaacaaaa tacataccag aattggatat gaaagatata
    22861 aacaatactt ctatagttgt agttggacct ccaatgatga tgaaatttac agtagaagaa
    22921 tttttaaaaa gagatttaga tgaaaagaac atttgggttt cttatgaaag aaaaatgtgt
    22981 tgtggaatag gtaaatgtgg acattgtaaa atggatgata cttacatatg tttagatgga
    23041 ccagtatttg attattcata tgctaaaaat cttattgatt agggggcgaa gtttgtgata
    23101 agagatttaa ataccaaaaa agtaatgaaa aatgcttata gaattacaaa aacaaaatat
    23161 gagacttctt taagagttag agtacctggt ggtcttattg accctgagag tttagctgta
    23221 gtttctaaaa ttgcaagtga gtacggaaat ggacaggtgc acataactac aagacagggg
    23281 tttgaaatat taggaataaa tatggaagat atggaagaaa taaataaaat tatacaacct
    23341 gttattgaaa aaatgaatat aaatcaaagt gagaaaaacg caggttatcc agcagcaggt
    23401 acaagaaata tagcagcttg tataggaaat aaagtctgtc caaaggctca atataataca
    23461 actgaatttg ctaaaagaat agaaaaagct atatttccaa atgatttaca ttttaaagtg
    23521 gctttaactg gttgtccaaa tgattgtata aaagctagaa tgaatgactt tggaattatt
    23581 ggtatggctt taccaatata tgaaaaagat agatgtgtaa attgtggagc atgtgtaaaa
    23641 aaatgttcta aaatatctgt tggagcatta aaaacagaaa ataataaggt ggtaagagat
    23701 aaagataagt gtataggatg tggagagtgt gtactaaatt gcccaacaaa tgcatggact
    23761 agagatgaga aaaaatacta tagattagct ataatgggta gaacaggaaa gaaaaaccct
    23821 agactagcag aagattttct tttatgggta gatgaggaca gcataataaa gataatactt
    23881 aatacttata gatatgtaga aaagtatata gataaagatg caccaggagg aaaagaacat
    23941 ataggatata taattgatag aacaggattt atggaattta aaaaatgggc acttgaaggt
    24001 gtagagcttc cagaaataac taaaatgtac gaaaacatat actggagtgg aattaaatat
    24061 ctataaattg agtaaaacat atatttgaat aaattaaaat ttaatagaag gaagagggaa
    24121 ttatgcataa agaaactttg gataaattaa ctaatgcagc tataaataag ataaatttat
    24181 taaacacaag taaagtaaaa tatttggtat cttctgcgtt tgcaggactt tatgtaggta
    24241 taggtatact tttgatattt actataggag gacttttgac tgatgcaggt tcacctatga
    24301 ctaagatagt aatggggtta tcatttgcaa tagcactaag tttggttata atgacgggaa
    24361 cagagttatt tactggaaac aatatggtta tgtctgctgg tatgttaaat aaaggtgtaa
    24421 gtataaaaga tacttctaaa atatgggcat acagttgggt aggtaattta atcggagctt
    24481 tggttttagg tcttatattt gtaggaactg gtctagtaga caaaggacct gtagctgaat
    24541 tttttgcaaa tacagcagct agtaaagcat ccatgccatt tacagctctt ttctttagag
    24601 ggattttatg taatattcta gtatgtgtat cagtgttgtg ttcgtttaga actaatagtg
    24661 atactgcaaa aataattatg atattcttat gtttatttgc ttttataaca tcaggttttg
    24721 agcatagtgt agcaaatatg acaatttata gtgtttcatt attttcacca acaataagta
    24781 cagttactat tggaggagct atttataatt tagtagctgt aacacttgga aatattgttg
    24841 gaggagcttt atttatgggt cttggaactt atatattagg taaagaaaag cttaattaaa
    24901 tttattgtat aaattataac tctcttgata aatacatttt tagtattatt gagagagtta
    24961 tttttatatt tttgaaaaaa tatttgaaac aaaaaaaata tgggagcata cgaaaatata
    25021 tcggttatat ataaaaaaaa tacgtttata tatgaattat atagttctaa atataaaaaa
    25081 agttaaagtc ctaccgtaaa aaagcgcatt ttgaataaga taacaaatat gataaaattg
    25141 gtcttgttga aatttttagg ggggatatga tgacaaagaa actagtaata tcaaaaacaa
    25201 agttgtttat ttttataata gcatttattt ctatatttat atatttattt ggaagtaaaa
    25261 atacacttat aggtgtaggt atagtaacag ctatgctaac actcttggaa agagatttaa
    25321 ctatttctcc aattaaaaat ttactgaagt atttagcaat aaatataatc ttaggaatac
    25381 tatcattttt tgcagtacaa aatatgtatt taggagtttt attaaatttt atagcattat
    25441 ttataatagg gtatgtattt agttatgact taaagagagc agtatatgta ccttttggtc
    25501 taatgtatat atttatggta agtatacctg taggaaaaag tgaatttcct atgagattgt
    25561 cggctttagc tgttggagca gttataataa tgattgctca atttgttatg aatagaaata
    25621 ggatgaaaaa tgtcggagat aaagaactga tatctatatg tgatgaatta ttagaaaaaa
    25681 ttagtctttt aaaaaatact attaatgatg atagttctat aattaaatct agtatgagaa
    25741 aaatagatag ctgtaattat agaataaatt ctatatctaa aaatttgaaa atggttattt
    25801 ttgataatag aaaagatgac ttttatatca gtattagagg tatagacata atgaatattt
    25861 tattttcatt agaaagaata agtttaatca tggaaagata caaaaaggat agtaaagaat
    25921 ttgaagatga agatataaaa aatattttag aagaaagtag cataaatagt aaatcagatg
    25981 ttctagttgt agcaacgaaa gaaataaact atattaagat gtgtttagaa aataaagata
    26041 ccataactga taaagagata ttaggattta gagattatgt tattgctcag gatactaaaa
    26101 atataaattt aaaagaaatt tatagtgttt tagaaaattt atatgagttt ttagtagatt
    26161 ataaaaaagt aaaatcaaga gacgaaaaga aagctgaaag aaaatcaaag atacctcatg
    26221 aatttaaacg actatcaata tataagaaaa actttaattt aaattctata agattttctt
    26281 atgcagtaaa gattgcttta gctacagctg tagcgggttt tattatggat tatttccatt
    26341 taagagatgg aagatggata atgttaactg tcttttcatt aacacaacct tacgcagaaa
    26401 attgtataca aaggtctaga aaaagaatag aaggtacatt tataggagct gtaatattta
    26461 ttgtattatt ttcaataata aaagatagta cattaaggtc gttaatagtt cttttagcag
    26521 ggtatataaa ctcttatgta gttgattata gaaaattaat ggtatgtgta actgtttcag
    26581 ctcttggttc agcagtagtt atgggagacc caaatgtttt aaccataagc aggatttcat
    26641 atgtagcatt aggagcaatt attgcattaa tagtaaataa gtttatatta ccatatgatg
    26701 ctaaaacagg ctatcaacat gttatagaaa tgtataaagg aatagttaaa aatataattg
    26761 atgaagtcaa taagtctata gaaaatgtag ctgatgttta ctatataaaa aatttattat
    26821 tgataccatc acttattgaa gatagactta tgttgataaa tgctatatat aaagataaac
    26881 atcaagagga ttttttagaa aatcagaaat tactaataag taatatgtat aatctatata
    26941 taaatgttaa taaaaataaa ataaaagatg aagatgttga aaaaatattg agagatacta
    27001 attatatttc aaattacaat gtagataagt atgatgaagg aagaagtgta attttagaga
    27061 gtattgtaaa tactaaaagt ctaggtgaca agataatatg tctaaactta ctgcaaactc
    27121 taaatggtgt caaagaaatg tatagaataa gtaatataac taaagtttca ataaaagaag
    27181 cagcttagat attaaattat agaatagcca tatatttaaa ataaagtata tggctatttg
    27241 ttttataaaa tactaaaaga aaataatata taaaaaacaa aaaacatata tttatgaatt
    27301 ttatatgaaa atagttaaaa tattgatttt tttcattggt tgaaaaaaca atttacttag
    27361 gataaactat aatagtattc aaatattatg ggggttagat ttatgagtaa agatgtaaag
    27421 gtaaagcgta ataagaaata tgatacattt agtataacta tggaacttga gagaccttta
    27481 ctttatgatg aggttgagaa caaagatgat aaaaataata atagaaaatt taacataaag
    27541 aataagatat ttaagggaat aggtatacta tttgtattga ttttgcttgg ctttttcata
    27601 tggataaata aaacatatga acctcaaaag ctggcaaaag aagctctagt cagcaatagt
    27661 aaagttgaag taactgtaaa tgaaaacatt tcatttacac caaaaggaag aaaagtttct
    27721 aaaggtttaa ttttgtatcc aggagctaaa gtagaaatag aatcttatgc tccacttgca
    27781 agaaaaatag cagaaagtgg atatgaggtt gtaatcgtaa agatgccact taatctagct
    27841 atacttggaa ctaataaggc acagaaagtt atggattctt acaacaacat agaacattgg
    27901 gtaataggag gtcattcatt aggaggagtt gcagcatcaa attttgcacg tgataataaa
    27961 ttaattgaag gcgttgtatt tttagcttct tatccaatgg gtgatgagtt gaaagaatta
    28021 ggaaaaaaag ttatatctat atgggggagc aaagatggag tagtcaattt taaaagtctt
    28081 gtagaatcaa aacaaaaact tcctgatgat acaacttatg ttgagattga aggaggaaat
    28141 catgcacaat ttggagacta tggaaaacaa aagggagata atgatgctat tataagtcaa
    28201 gaaaaacaac ttaatattac tgccaatagt atcattaaat ttttaaagaa tatatcttaa
    28261 actaaaattt aaaaaatata attttataag ttattattta aagtaaatat taataatata
    28321 atagaatgaa tattttatta caagggggat tttaatatgg aatacgatat gccactttac
    28381 agaccaccaa gtgaggctta tagtcttata atacaagtca cactaggatg ttctcataac
    28441 aaatgtacgt tttgtagtat gtacaaatct aaaaaattta aaataaagcc actagaagta
    28501 ataaaaaatg aaattgatat atttagaaga tattataagc atgtagaaag aatattctta
    28561 gcagatggag atgcattgat aataccaatg gagaaattaa gagatattat tttatatata
    28621 aaagaagttt ttccagagtg tgaaagaatt actatgtacg gctctcctaa atctatagag
    28681 aaaaaatctg atgatgaact taaagaatta agaaaacttg gtgttaaaat gatttatcta
    28741 gggcttgaaa gtggaagcaa tgaagtatta gaagatatta agaaaggttt tagtagtgaa
    28801 caattaataa aagttggtag aaaagttaaa aaaagtggga ttaaattatc agccactgta
    28861 atagcaggtc ttggaggaac taaaaaaaca catcagcatg cagttgatac aggaaaaatg
    28921 ttaggagcaa tttcaccaga ttatgtgggt gtacttagtt taatggtaga acctaatact
    28981 gaactttacg atttacttaa ggcaggagag tttacaatac tagaggataa ggctgtgtta
    29041 caagaaatta aagagatgat aaagaatata gatgctaatg aaaaaattgt atttagaagt
    29101 aatcatgcat caaattatgc taatttaaaa ggtgtattac ctgatgataa acaacgtcta
    29161 attgatgaaa ttgattacta tctaagtaac caaaagctaa aaagagaaga atatagaaga
    29221 ctatagtttt tgatatatca atctatattg ataggtaaat actaagatta tttagataca
    29281 aaaaatcatg ctacattaat agttgcttac tactgatgta gcatgatttt tttattaaaa
    29341 aacaaaatgg tatattcata tataatatat caataataat gaaaatgtga actagtttaa
    29401 tagaatttta cctattataa taaaaacagg aatttaaata ataaaaagta aagtaacttt
    29461 ttattaagta actttacttt ttatt
//
LOCUS       DAMJYN010000045        29062 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.046, whole genome shotgun sequence.
ACCESSION   DAMJYN010000045 DAMJYN010000000
VERSION     DAMJYN010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 29062)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29062)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29062
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.046"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            29..904
                     /locus_tag="PC466_002188"
     CDS             29..904
                     /locus_tag="PC466_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase"
                     /protein_id="HDF2769570.1"
                     /translation="MITFDVNGAIIRFDDTKNNYNKIRKIFKLYALEISKNFERDCLN
                     SFQNLKQISDRGLSLGEKYIEESFKKGIETIVSFGIITIDIDTFKSVYCEKYLDFKRL
                     FNNLNKTFIIPNKNKKNGHASFLEIESTIKKMSNYLYNDCFKIHYAVVDALIENRITA
                     VHSYIDEESIKKSNALFNNYKDGFIGKADECKVVKQIITLNPYREDVYEFLVKEDGDF
                     SKEIERLTEFLGYDIKEYKASLMDIYINELMESDENDVENAKEKIEKYARYIGCSDEN
                     LYVARVNAIYTFANA"
     gene            1265..2563
                     /locus_tag="PC466_002189"
     CDS             1265..2563
                     /locus_tag="PC466_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase/BAAT N-terminal
                     domain-containing protein"
                     /protein_id="HDF2769571.1"
                     /translation="MKVNVYNVESFVDERLKIMVSDLIPNTKLKISVKMEFPWCKGEE
                     FSSYGVFCSNEKGEVDLDLVEPIEGTYKADNCMGLIYSLEKSKTEGKNFAENISIDKP
                     IIMNMIFETSTERKEVELKRIFKSEDITTKYISDEFIGKLFYKQNSNNKTILMLGGSD
                     GNLDALDLLAAPLASRGFNVLTVAYFALEGLPDKLEEVPLEYFEKVFEWISENEITST
                     KEIFVHGTSKGGELAFLLASRYEQIKKVVVSQPHIYCFQALNGLMSGNDTSSWSYKGE
                     PFPYIKVDNDIFFEEQKKNISKGIPFGFNSTYKKSLKRAENRKEARIKIENSKADILM
                     IAGKEDNIWNSYEACLEALEIFEENNYPYNVELLTYNNMGHPLPIPYIMPLKETLCMS
                     MSGGIFSSGGTVEGNSKGQFESWNRTIEFYKKLLSSDLNN"
     gene            2753..4144
                     /locus_tag="PC466_002190"
     CDS             2753..4144
                     /locus_tag="PC466_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="benzoate/H(+) symporter BenE family transporter"
                     /protein_id="HDF2769572.1"
                     /translation="MERLARREQPHIKFGMFKIRIPFIHYRFEKPEAIQGIISSMTSL
                     GTIGLSTQILGLPYEVAWSMAIINSILYCLHVFMGDPVVPGWITASITLTTAYLLKFS
                     MGIERIQALTALQIDLGIIFILMGITGVAGKLVSKIPNSIKGGILMGVGISTIISEFN
                     PKGRFDSYPISITVGILVACFVMFSERFDTLKVKNKFLFHLGEYGVVSAILVSLIVGI
                     FSKEIEIPRFSFDNLVYIVDFKNLINTVSPFGIGFPSVMLFIQGIPMAFMIYIIAFGD
                     FITGENLVLSESENRKDEYIDFNSNRSNVISGIRNIFMAIFSPYIPMCGPLAATLTGS
                     VAQRYKVGKEAMQSVFSGMGTLVWVSAIFICFYPIAQIATPLIPLALSVTLLVQGYLC
                     TKLSMELCNTGVEKGLIGLMGGVIAAKGGTWGLAVGFILYFILIDSKKRKEKDINSIE
                     DCVYEILDKKKSI"
     gene            4321..4908
                     /locus_tag="PC466_002191"
     CDS             4321..4908
                     /locus_tag="PC466_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2769573.1"
                     /translation="MPPKVKITKEMILNTVLDITREVGFEAVNARSIASKLQCSTRPI
                     FTCYENMNELKNEFLAFAYEYYNQYVVNYRNSKSVSPYLLLPLSYIEFAQEETYLFKL
                     LFINDLDLMMKEANDFYKEIDNEKKARLFSESIGIELECAKVIFLDLFLYTHGIAVLT
                     ATKKLTLDRYSAEKMLKNILTAFIRQEKPDWNLSI"
     gene            4941..5732
                     /locus_tag="PC466_002192"
     CDS             4941..5732
                     /locus_tag="PC466_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDF2769574.1"
                     /translation="METKQYLIDFYNTYDEDSRLALKHGMVEFLTTMHYIDKYIKSGD
                     CVLEIGAATGRYSHTLARQGYDVDAVELVEHNIEVFHKNTQSNENISITQGNAMDLSV
                     FPDNKYDITLLLGPLYHLYNKEDKQQALHEAIRVTKPGGVVFAAYVISDGCLIDEGFH
                     RGNINVSEYIEKGLIDPQTFAAKSEPKDLFELVRKENIDDLMSAFNVTRLHYVASDGL
                     ALYMREAVDSMDDDAFALYLKYHLATCEREDLVGVTSHAIDIFRK"
     gene            complement(5913..8330)
                     /locus_tag="PC466_002193"
     CDS             complement(5913..8330)
                     /locus_tag="PC466_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2769575.1"
                     /translation="MFRNNNRTFIRKIALNDLKINKLKTYLSGIIIMISTCLLLTVTL
                     VSYNASVDLVNASPYHAIYKSVDEKAKNILYKDKNLSGVGTYKLIGSNKKTDCIMSIV
                     YADDTAIKLMNFQPLKGKLPTNKNEIAISEKYLQEFGLDKDIGDSIKLNYYDDITNKE
                     VQCDFIIVGFLENYYQDNAKQYYTVVSNDYFKNIASTPLQNKSNTFDESRPDTVDVLV
                     KLSEENTEKDSASIKTQLKKIGLSLGIKKYNIYLNDNYIESNLIDGEQIITVLVVGIV
                     VLFSSVFVIYSIFYISVVNSVQMYAKLKSLGMTSFQLKKTISLQGNILSIIFIPLGAI
                     ASCIIAYIIQPLAWQMIADLFIILILSLVMFLTVRISLFKPARIISKISAIEAMQYTE
                     TKFRKQAKNFSYINIKNLALKNIESNRKKNLIALISLSISGVLFISIANLANSIDFKK
                     QLSQQFVYNEDYIISIKSDNLYEHITEIQQNNPLTDSLKNEIKSIHGVKKLIESKSIK
                     SNIIEPYIKDRDEKQFITLIKGITPELSKSLEEYIVSGKIDYTHLDSDSLIINKYRTK
                     SYGLNLKVGDTVTFNIFSGNDIIKKKMKIIGIIDNSNTGGMFFASDKTLESLTPYNTN
                     LDFSILIDKKHSKEVEEKLLSIIQKNSNLMLYSYEDDYRMITRAFQYIIIASYIFVGL
                     ISCFGILNMTNTLINSVLIRKKEFALLQAVGMTRKQLRNMLYREGLNISIKAICTSSI
                     LGYFGSNLLCTFIKDVIRLDFINFKFSIFTILIFSFVLIGIQVLVTELLIRNIEKKSL
                     TERLRSQ"
     gene            complement(8343..9008)
                     /locus_tag="PC466_002194"
     CDS             complement(8343..9008)
                     /locus_tag="PC466_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2769576.1"
                     /translation="MSILQVINLKKYYGQSSNITKALDGVTLSIEKGEFISIVGTSGS
                     GKSTLLNMMGGLDNPTSGKVIIKGKELSTMTDEQLTIFRRRNIGFIFQNYNLVPLLNV
                     YENIILPIGLDGETIDKDFINEIINMLSLEEKLYDMPSNLSGGQQQRVAIARALVTKP
                     AIILADEPTGSLDSRTSSDVLSLLKVTSKKFNQTIVMITHNNEIAQLTDRIIRIEDGK
                     IVN"
     gene            complement(9090..10121)
                     /locus_tag="PC466_002195"
     CDS             complement(9090..10121)
                     /locus_tag="PC466_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2769577.1"
                     /translation="MNFKKFSFSSIYLIIAVGIIFTAILFNISIYLITDDLKLIALLL
                     IYTIVLCGFIALIIFLLHKKIVIFCSKICHTLDSMMNSEDNIEIELEEETILSRINHR
                     LIRMYEVIQENRNSIAIEKADLQELVSDLSHQIKTPIANLKMINTTLLNQTFKTEIQK
                     DFLMDMENQLDKLDFLMQSMVKTSRLETGIITLSKKKNSIYETIATALSGILFDAEKK
                     NIEVTVDCDPNLYIIHDKKWTSEAIFNILDNAVKYTNSNGKIRVATECWVMYTKIDII
                     DNGKGISESHQAEIFKRFYREEDVHDIEGIGIGLYLSRKIISLQGGYIKVTSDIGKGS
                     TFSIFLPNK"
     gene            complement(10111..10797)
                     /locus_tag="PC466_002196"
     CDS             complement(10111..10797)
                     /locus_tag="PC466_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2769578.1"
                     /translation="MEKILVVEDDSILNKTLSYNLIEDGYIITSKFTAKSALKSIFEC
                     EFDLIILDINLPDKSGFELCNEIKENYNIPIIFLTANDMECDMIKGYELGALDYITKP
                     FNINLFKQKVKAFLNHLTTKTKQDYYRDGYLEINFSELSANINGNQIIFTPLEYRTLK
                     LLTENPKSILTRKVLLEKLWDIDANFVDEHTLTSVISRIRSKIEKDNLKYIKTVYGMG
                     YMWLGERNEF"
     gene            complement(10955..12019)
                     /locus_tag="PC466_002197"
     CDS             complement(10955..12019)
                     /locus_tag="PC466_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S ferredoxin"
                     /protein_id="HDF2769579.1"
                     /translation="MKRVDERNTMFARANYKKDSTAYNDYYKKNPDKKEIDDSIRNRP
                     NLCSEGTMTYNELNSPMASSAFDFLSDIKSLCEGKVSDTKVDVDAKSMTKKIKGLAKQ
                     YGASVVGITKLKDYHIYTNRGRHEENYGEEINLTHKYAIVFGCEMDKEMINRAPMICE
                     VIETSKCYVDASIVGMILSYYIRNLGYDARNHMDANYLVMPVFIARDAGLGDIGRNAI
                     LTNKDYGSRLRLGVVTTDIPLLEDEYVDFGLEDFCKVCKKCSFNCPSHSLSNDIKIGD
                     DGKYNWVIEHETCYIKWRYLGTDCGMCISACPFSQNLETIKNTTSFKGNNELIQKALD
                     EYTSKFGKRIFIPGNPSWLK"
     gene            12281..12952
                     /locus_tag="PC466_002198"
     CDS             12281..12952
                     /locus_tag="PC466_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2769580.1"
                     /translation="MNLLIIEDDINLNEGLFYAFENDGFNVFKAYTKQEGLNIFNSKN
                     IDFIILDCNLPDGDGFDVCQIIREKSDIPIIMLTARDSEIDEVKGLEIGLDDYITKPF
                     SLSVLKARVKVAIRKKSNNKVIYSNGIKLDQKLLKVYKNKACLELSSVEYKLLSYLIE
                     NKGQILLKEQILHHIWDSEENYVDDNIVSVNIRRLRVKVEDDPSNPKYIKTAYGMGYL
                     WNEVE"
     gene            12954..13862
                     /locus_tag="PC466_002199"
     CDS             12954..13862
                     /locus_tag="PC466_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2769581.1"
                     /translation="MFILAFIICTVVIFIVSTKINQRRYDELNLMLNQILEGKEVTYP
                     DTKDTRASKISHQVKKIKDMIEIEVEQSKSEKEAIKGLISNMSHQLKTPLSNITIYCE
                     LLENINISTLQKKEFLQKMKNETFKIDWLLQSLFKMTKLEDGVIEFEVEELLIKDTLI
                     QSISTIFNKSEAKNIRINLEPFSDIKLVHNKKWTIEAIVNVLENAIKYSPSDSTITIS
                     VIKMELYTKITIKDEGIGIDSRELNDIFKRFYRSKNVENQNGTGIGLYLTRLILEKEN
                     GNIIVESKLGSGCCFSIFLQNCKSLN"
     gene            13939..14625
                     /locus_tag="PC466_002200"
     CDS             13939..14625
                     /locus_tag="PC466_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2769582.1"
                     /translation="MSILVTNNLVKHYGKGETKVKALNGVSIEIERDTFTAIVGTSGS
                     GKSTLLNIIGGLDNPTSGDVIIKGKNISKIGKKDLTVFRRRNIGFIFQNYSLMPVLNT
                     YDNIALPVTLDKGNHIDHEYIEMLMKTLGIWDKRLKFPSELSGGQQQRVAIARALANK
                     PALILADEPTGNLDSKTTMEVVCLLKESSAKFHQTILMVTHNENIAQVCDSIIHIEDG
                     VVVNTGGEVL"
     gene            14622..17177
                     /locus_tag="PC466_002201"
     CDS             14622..17177
                     /locus_tag="PC466_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HDF2769583.1"
                     /translation="MMSLVKFSIQYIKHYKKQSISIVLSIVLSVALLTGIGSLVHSAD
                     KSRIEKIREDSGDYHYFYKVDKEQLNKIKKNKKSKEYIVDRLGVTKPKNQIDEPFIIE
                     FLNADSSYLDMTGRKLLKGTLPSKDGEIVLDTYSLNNLNVNKEIGTEINLDGKIYKLC
                     GILSSLSNPETAMEGFVNDYLQPKEKDSYIVYVKYDENKNIKKQNYKFMKKFNISKEK
                     TYINWPLSVEFGVKPPKNIEKYNIFEFLKNLELNTNAIILLVGVFGAAAVYSIFHVSI
                     LQRISQYGVLEVLGANNKQLLFLLFLELFLLFIVGFPIGCFLGIGVASTIYEQFPHIF
                     LSSDIVPGAFFISEKSIYLGFLFILLLLILIAVRVVHQLNKYSSIESMKNFKITNKKK
                     RILESVKHSNMTKVLSHKYMTQKRGMFIGILFSLSLGGIIFLCSSYSIQLTKNNNELT
                     MKADDGLNSDYQITMQTTDFDVGIPKDKISRLNNVEGISKVYPVRYLFGAMQIKEEQL
                     FWKNFFKPLEKDYRIKTFFDGICTKQNEGGYLLKTNIYGYNNGMLEGLNSYIIDGEIN
                     THDMVKNNKVIVRLPMDGTGMYDAVDINPGDTIKVKVPKTMKPTGEIVKFKEENKNDY
                     TTKEFVVAATVKRVMANNIYFIGDYGMDIVMTNGQMKNNFDIENYNSVSIKKTEDSNS
                     EELSENIKSVVSDVKRCIVTDYTIAIEKNNTYLNQKLLFIYGIVFVLLAISLFHIINT
                     VSYLIFSRRHEFGILRAMGITDNKFLLMMIREGFLYGFYASIIMVIGSVIGQFMIYFM
                     VKRVYLYINPILKINTPLYIGMIILNITISIVAVIIPVRQILKSDIISEINKS"
     gene            complement(17371..18570)
                     /locus_tag="PC466_002202"
     CDS             complement(17371..18570)
                     /locus_tag="PC466_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003493023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coenzyme F420-0:L-glutamate ligase"
                     /protein_id="HDF2769584.1"
                     /translation="MDRLVGTVSRGVRAPIIRQGDDLVKIVVDSVLNASKSENFEVRD
                     KDVIAVTEAVVARAQGNYAHVDNIAKDVKDKFGDDTVGVIFPILSRNRFAICLKGIAK
                     GCRKVVLMLSYPSDEVGNHLISIDELDDKGINPWSDVLTEEKYRELFGYNKHTFTGVD
                     YVDYYKNLIKDCGAEVEIVFANNPKTILNYTTSILTCDIHTRQRTKRILRQNGAKKVY
                     SLDDIMTASVDGSGYNDQYGLLGSNKATEETVKLFPINCDEVVNKIQGNIKEITGKDV
                     EVMVYGDGAFKDPVGKIWELADPVVSPAYTKGLEGTPNEVKLKYLADNDFADLSGDEL
                     KEAISKYIVEKDNKSDDLTGNMVSQGTTPRRLTDLIGSLADLTSGSGDKGTPIIYIQG
                     YFDNYTK"
     gene            18689..19576
                     /locus_tag="PC466_002203"
     CDS             18689..19576
                     /locus_tag="PC466_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDF2769585.1"
                     /translation="MNIKLELYKVFNAVVNNKSFSLAAKELFMSQPAVSQSIKQLEEQ
                     LDTLLFYRNNKGVKLTPEGKILSEHVTTALKLISSGEDRINKFKKLEYGSLKIGVGDT
                     AARFFLLKYLEIFHKKYPHIHVSTINRTSRELISLLKDGNIDIAIINMPIEDDTLNIV
                     ECIEIHDIFVCANDYIEYKGRKISLEELNTLPLIMLENKANSRLYVNEYFLSKGIKLN
                     PDIELGSHELLLEFAYINLGVSCVIEEFSIDYLENEKLFKLDIKEPIPKRNIGYCHLK
                     DISLSLATKEFLSMISNNI"
     gene            19766..20323
                     /locus_tag="PC466_002204"
     CDS             19766..20323
                     /locus_tag="PC466_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2769586.1"
                     /translation="MSDSEYPQMKTLETRSCILRPASLDDVEDFFDCYKNKIVVKHLP
                     FSEHKSLEDTRKFIKSFFLNPYKKGKIGHFAIVYKRDNKVIGNMGFNNINPKALEAEI
                     GICINPSYWGHDFATEITKRVIQYGFRELNLNKIIAITYEENQNSTKSLDLLGFKCTG
                     KYIKKIHTGNTVKNVPCYQYELKKQ"
     gene            complement(20563..21423)
                     /locus_tag="PC466_002205"
     CDS             complement(20563..21423)
                     /locus_tag="PC466_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HDF2769587.1"
                     /translation="MKKQKSPILLEMLGLFLGCISMSIGINMFLKPHTIAPGGLSGLS
                     LVLNKVTGLPVSAIMLIIGVPLVILAFRIMGTKNSLKTLFGTVVFSAIVQLTDPLSKL
                     RFTNDLLLSSIAGGILVGIGLGIMFKSDASTGGTDLIALILSKKFPGIKATKFMSCLD
                     GMVVISSGIVNRSLETALYSGIALCVLIKIADMIMEGFDHSKAFFIISDEPESLRQAI
                     TEELDRGLTILDGKGGYTRENKEVLLVVVSKKQELYLKRLVKRTDPTAFVIVTDVHEV
                     LGEGFKNLEN"
     gene            21922..23325
                     /locus_tag="PC466_002206"
     CDS             21922..23325
                     /locus_tag="PC466_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2769588.1"
                     /translation="MHKPSYKTVFHSYIIFFMIFICLILTVIGIFLSLITIQKPNGEF
                     IRSDWPKKFTENFNEQIIFIDNKPQVKQSGLEKLRENQLWLQILDSSGNRVYGFLEPK
                     EHKDYYSNSELLTLANQNNSSNGTVYFNTIKNNKNDYIYIIYFPLNISKVNMFFDGSK
                     FVGGKSIVFSIIGIIFLIILISGIAYGYWVTKCISNITSAVSDISKRSYLPVNIKGVF
                     ADIYNSLNILNEEIHRSDEIQNKTDIMREEWISNITHDLKTPLSPIKGYAELLTDSST
                     NYSPEKVYKYASIMLKNIEYTNTLINDLKLTYQLKNGIIPLNKNKYDLVRFLKELSID
                     ILNYPEYESNIVEFKSNIDNINFDFDCTLLKRAFSNLIVNAFTYGDKNTKVCVHITLN
                     ERIEIIISDNGKGMSREEASNLFNRYYRGSNTKQKIEGTGLGLAITKQIIEVHGGNIS
                     VESIPGLGSSFYITFPI"
     gene            23545..26022
                     /locus_tag="PC466_002207"
     CDS             23545..26022
                     /locus_tag="PC466_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HDF2769589.1"
                     /translation="MKIILKYIFTNIKERKIRTAVMLLSIVLSTVLLFVSFSIGLSYE
                     SAQRKMAKGMYGTATISVQSKNPDVLTNLEDIPDLNAIKSKVGVLESSAIYNKGGYYE
                     EFSLISADLSQLNKINKPRLENGDSITDFSGDKIILPNRFTSKYKIKKGDSITLQIYG
                     KSYTFQVSDIASYDTVFLRNTRGVNALLPKETLSKIINKGSGYTRVLIESEEEMTENL
                     VNKLSEELSTEKYMVSNTINETKIISDARQKTMPFFLISFFALTLSIFIIYSSYKVIT
                     LERLPFIGTFRSIGANEKTVTRILMLESILYGSIGGLIAIPIGVVVLNLMLHGLGNSL
                     EQGISIPVVISPIGVIISVIVAIIVSSFSAYIPVKKASHLPIKNIVLGTVEEKNVSNR
                     SILFIGSIMFILSILLPRISPENTLYLAGGFSLLGLIVATIVLIPLITDIMSIVFEFV
                     YKNILGNEGKLAARNMKNNKNIIQNITLLFISISAVIAISVVGNFVKTYITDVFRDAE
                     LQGFADGKMNEEFIENVRHMDGIKKILPLYVMNNEISGNGVTLSRLEGTDNIKLYNSM
                     FGINYTNFEIKKQVIEAFNDKRSVILNEDTLKKVGLSIGDTITLSNDKYDFSYKIVGS
                     FKSRANDVEAVIPSHYAVNDFDKTNYGFLVYTAVNPDVVMIQIRDLFGDTYNWSRTVE
                     EFNNDSLNTISSFLSPMNKMTYFIFLLATVGIINNLLINYIQKKRSIAMYKSIGLSDK
                     QNIKVTLIEGFTSGLLGAVIGIVISILEIQTIFIVAGPKISMKPDLDFKTFIIVGLLG
                     IIVTLIGSIVPIIKGKKMKLIEEIKFE"
     gene            26037..26723
                     /locus_tag="PC466_002208"
     CDS             26037..26723
                     /locus_tag="PC466_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2769590.1"
                     /translation="MKITHNSLAVEAKNIIKEYKIGNTTTRVLKEVSLQVMKGEFVSI
                     MGQSGSGKSTLLYILGGLDTPTSGKVYMNGADISHFNDEKMSIIRRRNIGFVFQFYNL
                     IPNLNVEENIMLPLLLDGKNLKDYKNQLDEILDIVGLTDRRKHTPRELSGGQQQRVAI
                     ARALVGKPEILFADEPTGNLDSKTGIEIIDLLNKINRDNGQTIIMVTHSPEAAKSSSR
                     TITVSDGLIV"
     gene            26996..27829
                     /locus_tag="PC466_002209"
     CDS             26996..27829
                     /locus_tag="PC466_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2769591.1"
                     /translation="MLKKESIHFINKNRSLIVCEDNFVYLLPCMQLKNWISNFTISFP
                     NQTIISDNYTIIPHGSVTLVFFYDATGLHSLLFGPTTKPKTVGNIANRCDVILIIEFQ
                     PAGFFPLIGIQQSELIDKVVPFSIINTSLDLEIKKIFNESLSIDKLILKLEELLISNI
                     KIEYSYEFILAIQLIIQNSGNISSQEISKKVFYSSRHLNRLFNQYLGLSMKSFSRLVR
                     INKSIKLLNNNKTSLMYICNELGFYDIPHFIKDFKIVCGITPQKYRANMSDFYSEIAK
                     F"
     gene            27867..28328
                     /locus_tag="PC466_002210"
     CDS             27867..28328
                     /locus_tag="PC466_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase/bleomycin resistance/dioxygenase
                     family protein"
                     /protein_id="HDF2769592.1"
                     /translation="MKFGGVLLIVKDINKSKKFYEDVMEQKITLDLGEHVSFENGFGL
                     QSNYKAIIGYDLPIYQQSNNFQLYFEVNDIKQWESKINRIGNIEFLHYIKEYPWGQRT
                     FRFYDFDKNIIEISESMESVIKRLLKQGLALEEISKRTMYPVEFITQFQQL"
     gene            28481..28906
                     /locus_tag="PC466_002211"
     CDS             28481..28906
                     /locus_tag="PC466_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012201185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDF2769593.1"
                     /translation="MHDELKIKMYSFTMDCKDPHELAKFYAALLNWEIAFYNEEYACV
                     GAPGTNQGTYPGITFQRNSEYKPPVWPEKPESQQQMAHMDFAVNDLEEAVQYEIHCGA
                     TIAEEQFTDDWRVMIDPAGHPFCLCQMKSIMESSHFSLL"
BASE COUNT        10959 a         3501 c         4299 g        10303 t
ORIGIN      
        1 atgaaactaa tggggaggtt aaaactcaat gattactttt gatgtaaatg gagctattat
       61 cagatttgat gatacaaaaa ataattataa taagataagg aaaatcttta aattatatgc
      121 tttagaaata tctaaaaact ttgagagaga ttgtttaaat agttttcaaa atctaaagca
      181 aatatctgat agaggtttaa gtttaggaga aaaatatata gaagagtctt ttaagaaagg
      241 aattgagact atagtaagtt ttggaattat aactatagat atcgatacct ttaaaagcgt
      301 ttattgtgaa aaatatttag attttaagag actttttaat aacttgaata aaacttttat
      361 tataccaaat aaaaataaaa aaaatgggca cgctagcttc ttagaaatag aatcgacaat
      421 aaagaaaatg agcaattatt tatacaatga ttgttttaaa attcattatg ctgttgtaga
      481 tgcccttata gaaaatcgta taactgcggt acattcttat attgatgaag aatctataaa
      541 aaaatctaat gccttattta ataattataa agatggtttt attgggaagg ctgacgaatg
      601 caaagtagta aaacaaataa taactttaaa tccatatagg gaagatgtat acgaattttt
      661 ggtaaaagaa gatggagatt ttagtaagga aattgagaga ttgactgaat ttttaggcta
      721 tgatataaaa gaatataaag cgtcattaat ggatatttat ataaatgagt taatggagag
      781 cgatgaaaat gatgttgaaa atgcaaaaga aaagattgaa aaatatgcta gatatattgg
      841 atgtagtgat gagaatttat atgtagcaag agttaatgcc atatatactt ttgcaaatgc
      901 ataattttat taaacattaa atattagatg ttcaattata taaatttaaa taaaaaaata
      961 tccttattaa taacaaatag tttatattaa aaaccattct taaaatgagt ggttttttat
     1021 tttgaataga tatattttaa acctaatagc attcctatct ttaattagcc aaaaatcaac
     1081 tggatttcat atagactaca taattttaaa ttactaaaaa agacaatata ttgacaaaaa
     1141 tgaaatatgt tgataaaatg aaatagtcaa tatggtgtct taatttaaaa atttatttat
     1201 gttgtattag ataaagttgt tttatatata aagcataaat aattattata aggagaaata
     1261 gattatgaaa gtaaatgtat acaatgtaga atcatttgtg gatgaaagac ttaagattat
     1321 ggtttcagac ttaattccaa atactaaact taaaataagt gtgaaaatgg aatttccatg
     1381 gtgcaaggga gaagaatttt catcttatgg agtgttttgt tcaaatgaaa aaggagaagt
     1441 agatttagat ttagttgaac ctatagaagg tacttataag gctgataatt gtatggggtt
     1501 aatttattcg ctggaaaaat ctaaaactga aggtaaaaat tttgcagaaa atatatctat
     1561 tgataaacca ataattatga atatgatatt tgaaacttct actgaaagaa aagaagttga
     1621 attaaagaga atatttaaat cagaagatat taccacaaaa tacatatctg atgagtttat
     1681 aggaaaatta ttttataaac aaaattctaa taataaaaca attttaatgc taggtggttc
     1741 tgatggaaat ttagacgctc tagacctttt agcagctcca cttgcatcta gaggattcaa
     1801 tgtactaaca gttgcatact ttgctttaga agggttacca gataaattag aagaggttcc
     1861 attagaatat tttgaaaaag tatttgagtg gattagtgaa aatgaaatta ccagtactaa
     1921 agaaatattt gtacatggga catcaaaggg tggagaattg gcctttttac ttgcttcaag
     1981 atatgaacaa attaaaaagg ttgtagtatc acaacctcac atttattgtt tccaagctct
     2041 taatggattg atgagtggaa atgatacttc atcatggtca tataaaggag agccatttcc
     2101 atatatcaaa gtagacaatg atatattctt tgaagaacag aaaaaaaata tatcaaaagg
     2161 tattccattt ggatttaata gtacttataa gaaaagtctt aaaagagcag agaatagaaa
     2221 agaggctaga ataaaaatag aaaattccaa agcagatata cttatgattg ctggaaaaga
     2281 agataacata tggaatagtt atgaagcttg tttagaggca ttagaaatct ttgaagaaaa
     2341 taattatcca tataacgtag aattattaac atacaataat atgggtcatc cgttaccaat
     2401 tccatatatt atgcctctaa aggagacttt atgtatgagt atgagtggag ggattttttc
     2461 ttcaggtgga actgtagaag gaaattcaaa aggacagttt gaatcatgga atagaactat
     2521 tgaattttat aaaaaacttt tatcaagtga tttaaataac taatattaag tgatttaagt
     2581 aactaaaaat gaagcggttt ttctatatat gcacaaaatc tatcaatttt atagatttaa
     2641 tttattgttt atataatttg catgttatat actaatttta atgacattga caatttataa
     2701 acaattataa agttgtaaac ttataagagt tattgaaagg tggagtgaag ttatggaaag
     2761 actcgctaga agggaacaac ctcatataaa atttggaatg tttaagataa gaattccatt
     2821 tatacattac agatttgaga aaccagaagc tattcaaggt ataatatcaa gtatgacaag
     2881 tttaggcaca attggcctta gtacacaaat tttgggatta ccctatgaag tggcatggag
     2941 tatggctatt attaactcaa tattatactg tttgcatgtt tttatgggag acccagttgt
     3001 acctggctgg attacagctt ctataactct tacaactgca tatttgttaa agttcagcat
     3061 gggcattgaa agaatacaag cattaacagc tttacaaata gatttaggaa taatatttat
     3121 tttaatgggt ataactggtg tagctggaaa gttagttagt aagataccaa attctattaa
     3181 aggtggaata ctaatgggtg tcggtatatc gactataata tcagagttta atcctaaagg
     3241 gagatttgat tcttatccta tatctataac agtaggaatt ttggttgctt gttttgtaat
     3301 gttttctgaa agatttgata ctctaaaagt taagaataaa tttttatttc atttaggaga
     3361 atatggtgta gtatcagcta ttttagtgag tttaatagta ggtatattta gtaaagaaat
     3421 agaaattcct agatttagtt ttgacaattt agtttacata gtagatttta aaaatctgat
     3481 aaatacagta tctccttttg gaataggttt tccaagtgta atgttattta tacaagggat
     3541 accaatggct tttatgatat acataattgc ctttggtgat tttataacag gtgaaaactt
     3601 agtactttct gaaagtgaaa atagaaaaga tgaatatata gatttcaatt caaataggtc
     3661 taatgttata agtgggataa gaaatatttt tatggcaatc ttttctccat atataccaat
     3721 gtgcggtcca ttagctgcga cacttacagg aagtgttgct caaaggtaca aggttggaaa
     3781 ggaagccatg cagtctgttt ttagtggcat gggtacatta gtatgggttt cagcaatttt
     3841 tatctgtttt tatccaattg cgcagattgc tacacctctt ataccattag cattgtcagt
     3901 aacactttta gttcaaggat atttatgtac aaagctatca atggagctat gtaatacagg
     3961 tgttgagaag ggattgattg gacttatggg aggtgtaatt gctgctaaag gcggaacatg
     4021 gggacttgct gtaggtttta tactgtattt cattttaatt gattctaaaa aaagaaaaga
     4081 aaaagatatt aattcaatag aagattgtgt atatgaaata ttagacaaaa agaagagtat
     4141 ttaaaggaaa atatgagttg ctgttatcta ttaatagatt aattgcaact catgttttat
     4201 ttataagttt taggaattgc aaaaaaatgc aaagcttttt cttgacataa tttcttgata
     4261 tgttactata gttatataac atatgtgttt tataaaaatt taatggagag gtgaacatat
     4321 atgccaccta aagtaaagat aacaaaagaa atgattttga atacagtctt ggatattaca
     4381 agagaagtgg gatttgaagc tgtaaatgcg aggagtattg caagtaaatt acagtgttcc
     4441 actcgaccaa tttttacttg ttacgaaaac atgaatgaat taaaaaatga atttcttgct
     4501 tttgcatatg aatattataa tcagtatgtt gttaattatc gtaattctaa aagtgtaagc
     4561 ccttatttac tgcttccgct ttcatacatt gaatttgctc aagaagaaac gtatttattt
     4621 aagttgttat ttataaatga tttagatttg atgatgaaag aggcgaatga tttttataaa
     4681 gaaattgaca atgaaaaaaa ggcaagactt ttttcggaaa gcattggaat agagttggaa
     4741 tgtgcaaaag taatattttt agatttattt ctttatactc atggcatagc tgtcttaaca
     4801 gcaacaaaaa aattaacatt agatagatat agtgctgaaa aaatgttgaa aaatatatta
     4861 acagctttta taagacaaga aaaaccagat tggaatttgt ctatttgatg tttattaact
     4921 aatatagaag aggtgagatt atggaaacaa aacaatactt aattgacttt tataatactt
     4981 atgatgaaga tagtcgactt gcattaaaac atggaatggt ggaatttctc actactatgc
     5041 attacattga taagtacata aaatcaggtg attgtgtgct tgaaattggc gctgcaactg
     5101 gtcgttattc tcacacactg gcacgtcagg gatatgatgt tgacgcagtg gaattagtcg
     5161 aacataatat agaggttttc cataaaaata ctcaatcaaa tgaaaatata agcattactc
     5221 agggtaatgc tatggattta tctgttttcc cagataataa atatgatatt acgttactgt
     5281 taggaccact atatcatctt tataacaaag aagataaaca acaagcttta catgaggcaa
     5341 ttcgtgtaac aaaacctggt ggtgtggttt ttgctgcata cgttatatct gatggctgtc
     5401 tcattgacga ggggttccat agaggaaata ttaatgtatc tgaatatatt gaaaaaggtt
     5461 tgattgatcc acagacattt gctgctaagt ctgaaccaaa ggatttgttt gagcttgtac
     5521 gtaaagaaaa cattgatgat ttgatgtctg catttaatgt aactagactg cattatgtcg
     5581 catcagatgg tttggctttg tatatgcgtg aagcagtaga ctctatggat gatgatgcat
     5641 ttgcgttata tttaaaatat caccttgcta cttgtgaacg tgaagattta gtaggagtta
     5701 caagtcatgc aattgacata tttagaaaat aaggaatatg cttgtttatg tctctggtga
     5761 tgttgcttgg agatataagg aagtgtatct gtataaaata aaaacaagta gagggacaga
     5821 aaattatgta aagtcaaaat tttctatcct tttagctttt aaaaaattat gttaaaactt
     5881 gtataaaaaa tggttatttt ttatatacat tcttactgag aacgtaagcg ttctgtaagt
     5941 gatttttttt ctatatttct tataagtaat tcagtcacta aaacttgtat accaattaat
     6001 acgaatgaaa aaattaaaat agtaaatata gaaaatttaa aattaataaa gtctaatcta
     6061 attacatctt ttataaaagt gcaaagtaga tttgaaccaa aataacctag tatacttgaa
     6121 gtacatatag ctttgatact tatgtttaga ccttctctat aaagcatatt tcgcagttgc
     6181 tttcttgtca ttccaacggc ttgaagtaag gcaaactctt tttttctaat taaaacgctg
     6241 tttattaggg tattggtcat atttagtata ccaaagcaag aaattaaacc aacaaaaatg
     6301 tatgaagcta taattatata ttgaaatgct ctagtaatca ttctataatc atcttcatat
     6361 gaataaagca ttaaatttga atttttctga attatactta acaacttttc ttcaacttct
     6421 ttagaatgct ttttatctat taaaatagaa aaatctaaat ttgtattata tggtgttaga
     6481 gattctaaag ttttgtctga agcaaaaaac atacctcctg tattggaatt gtcaatgatt
     6541 cctataattt tcattttctt tttaataata tcatttccac taaagatatt aaatgtaact
     6601 gtatctccaa cttttaaatt taatccataa gattttgttc tatatttatt tataattaaa
     6661 ctatctgaat ctaaatgtgt atagtctatt tttccactga caatatattc ttcaagtgat
     6721 tttgaaagtt caggcgtaat acctttaatt agagtaataa attgtttttc gtctctatct
     6781 ttgatgtaag gttctataat attactttta attgatttgg attcaattaa tttttttact
     6841 ccatgaatag atttaatttc attcttaaga gaatctgtta gtggattatt ttgttggatt
     6901 tctgtaatat gctcatataa gttatcactc ttaatgctaa ttatataatc ttcgttatag
     6961 acaaattgtt gagatagttg ttttttgaaa tctattgaat tagcaagatt agcgattgaa
     7021 ataaataaaa ctccactaat gcttagcgat attaatgcaa tcaaattttt ctttctattt
     7081 gactcgatat tctttaatgc tagatttttt atatttatat aactaaaatt ttttgcttgt
     7141 tttctaaatt tagtttctgt atattgcatg gcttcaatag cagatatttt agaaataatt
     7201 ctagctggtt taaataaaga aattctaaca gttaaaaaca ttaccagtga taaaattaaa
     7261 attataaata aatcagctat catttgccat gctaatggtt gaattatgta agcaattata
     7321 caagaagcta tagcccctaa tggaataaaa ataattgaca aaatatttcc ttgtagagaa
     7381 atagtctttt ttaactgaaa agaagtcata cctaacgatt tcaacttagc atacatctga
     7441 actgaattaa caactgaaat ataaaaaata ctatatataa caaaaacgct agaaaaaaga
     7501 acaactattc caactactaa aactgtaata atctgctcac catcaattaa atttgattca
     7561 atatagttat catttaagta tatattatat ttcttaatac ctaaagataa accaattttc
     7621 tttaactgtg tcttaattga agctgaatct ttctctgtat tttcttctga tagtttaact
     7681 aatacatcta cagtatcagg tcttgactcg tcaaaagtat tacttttatt ttgtaaaggt
     7741 gtagaagcta tattcttaaa ataatcattt gaaacgactg tatagtattg cttggcatta
     7801 tcttgataat aattttctag aaatccaaca ataataaaat cacattgaac ttctttattc
     7861 gtaatatcat cataataatt taatttaatg ctatctccaa tatctttatc taaaccaaat
     7921 tcctgtaaat atttttctga aatagcaatt tcatttttat ttgtaggtag tttgcctttc
     7981 aatggttgaa aattcataag tttaattgct gtatcatctg cataaacaat cgacataata
     8041 cagtctgtct ttttattact tccaattaat ttgtaggttc ctacgccact aaggttttta
     8101 tctttatata gtatattttt tgctttttca tctacagatt tatatatagc atgatatgga
     8161 gatgcattaa ctaaatctac agaagcatta tatgaaacta aggtcactgt taataataaa
     8221 catgtagaaa tcattataat gatacctgaa agatatgttt taagtttatt aatttttaaa
     8281 tcatttaaag ctatttttct tataaatgtg cgattattat ttctaaacat atactacacc
     8341 tcctagttaa caatttttcc atcttcaata cgaataattc tatcagttag ttgtgcaatt
     8401 tcattattgt gtgtaatcat tacaattgtt tggttgaatt ttttacttgt cactttaagt
     8461 aaactcagta catctgaact agttctacta tcaaggctac ctgtgggttc atcagctagt
     8521 ataatagctg gttttgttac aagtgctcta gctatagcaa cacgttgctg ttgaccacca
     8581 gaaagattac ttggcatatc atataatttt tcttcaagag aaagcatatt tataatttca
     8641 tttataaaat ccttatctat ggtctctcca tccaatccta ttggtaagat aatattttca
     8701 tatacattaa gtaaaggaac aagattataa ttttgaaata taaaacctat atttctgcgt
     8761 ctaaagattg taagctgttc atcagtcata gtagataatt ccttaccctt tataataacc
     8821 tttccagatg taggattatc taatcctccc atcatattta ataatgtgga tttgccacta
     8881 ccagatgtac ctacaataga aataaattcg cctttttcaa tagatagagt tacaccatca
     8941 agagcttttg taatgtttga actttgtcca taatatttct ttaaattaat tacttgtaaa
     9001 atactcataa taatacctcc ttaacatctt gtaaatacag tataaaatca aaatgttgca
     9061 gaatcattac aaataaaata tttaaaaatt tatttattag gtaagaagat agaaaaagtc
     9121 gacccttttc caatatctga tgtaacttta atatagccac cttgaagaga tataattttt
     9181 cttgaaagat atagacctat tccaatacct tctatgtcat gtacatcttc ttcacgataa
     9241 aatcttttaa agatttctgc ttgatgactt tctgatattc cttttccatt atcaataata
     9301 tctatttttg tatacataac ccaacattct gtagctacac gtatcttacc attagaattt
     9361 gtgtatttta cagcattatc taatatatta aaaatagctt cagaagtcca tttcttgtca
     9421 tgaattatat ataaatttgg gtcacaatca actgtaactt caatattctt tttttcagca
     9481 tcaaacaaaa ttccactaag tgctgtagca attgtttcat aaattgaatt tttcttttta
     9541 gatagtgtga ttatacctgt ctctagtctg gaggttttta ccatagattg cattaaaaaa
     9601 tctaatttat ctaattggtt ttccatatcc attaaaaaat ccttttgaat ttctgtttta
     9661 aatgtttgat ttagtagagt agtattaatc atttttaaat ttgcaatagg agttttaatt
     9721 tgatgagata gatcagaaac tagttcttgt aaatcagctt tctctatagc aatactattg
     9781 cgattttctt gaataacttc atacattcta attaatctgt gattgatacg tgataaaata
     9841 gtttcttctt ctaattcaat ttcaatattg tcttcactat tcatcatact atctaaagtg
     9901 tgacatattt tagaacaaaa tataactatt tttttatgaa gtaaaaatat tattaatgct
     9961 ataaatccac aaagtactat tgtatatatt aataatagag caattagttt taaatcatca
    10021 gttattagat aaattgaaat attaaataaa atagctgtaa aaattatacc aacagcaatt
    10081 attaaataaa tagaactaaa agaaaatttt ttaaaattca tttctttcac ctaaccacat
    10141 atatcccata ccatataccg ttttgatata cttaagattg tctttttcaa ttttgcttct
    10201 aatcctactt ataacagatg ttaaagtatg ttcatctaca aagttagcat ctatatccca
    10261 gagtttttct aaaagtactt tccttgttaa aatactttta ggattttcag taagcagttt
    10321 taaagtacga tattctaatg gtgtaaatat aatttgattt ccatttatat tggcagataa
    10381 ctcagaaaag ttaatttcaa gatatccatc cctatagtaa tcttgttttg tttttgttgt
    10441 aagatgattt aaaaaagctt taactttctg tttaaataaa ttgatattaa atggttttgt
    10501 tatataatcc aaagctccaa gttcatagcc tttaatcata tcacattcca tatcattagc
    10561 agttaaaaaa attattggta tattgtaatt ttcctttatt tcattacata attcaaaccc
    10621 acttttatct ggtaaattaa tatccaaaat tattaaatca aattcacatt caaaaataga
    10681 ctttagtgca gatttagctg taaattttga agtaattata tatccatctt caattaggtt
    10741 atatgataga gttttattta atatagaatc atcttctact actaatattt tttccataca
    10801 gttactcctt ttagtttaat attttataat gtcaattata gactaaaaac attgctgaat
    10861 tgttataaac gagaaaaagt atttaaaaat ttatatattt aataaagaac ctgtcctatg
    10921 ataaattcta gtacagattc tttattaaat aaaattattt caaccaagat ggatttccag
    10981 gtataaatat tcttttacca aattttgaag tatactcatc taaagctttt tgaataagct
    11041 cattattacc cttaaatgaa gtagtattct ttatagtttc gagattttgg ctaaatgggc
    11101 aagcagatat acacatacca caatctgtac ctaaatatct ccatttaata tagcatgtct
    11161 catgttcaat tacccaatta tattttccat catcaccaat tttaatatca ttagaaagcg
    11221 aatgagaagg gcagttaaaa gagcattttt tacagacctt acaaaaatct tctagtccaa
    11281 aatcaacata ttcatcttct aaaagaggaa tatctgtagt aacaacacct aatctaagtc
    11341 tagagccata atctttattt gtaagtatag catttcttcc tatatctcct aaacctgcat
    11401 cacgagctat aaaaacaggc attactaaat aattagcatc catatgattt ctagcatcat
    11461 atcctaaatt tcttatatag taacttaaaa tcatgccgac gatagatgca tccacatagc
    11521 actttgatgt ttctataact tcacatatca ttggagctct atttatcatt tctttatcca
    11581 tctcacatcc aaatacaatt gcatacttat gagttagatt aatttcttca ccgtaatttt
    11641 cttcatgtct acccctattt gtataaatat gatagtcttt taatttagtt ataccaacta
    11701 cagaagctcc atactgcttt gcaagaccct taattttttt tgtcattgac tttgcatcta
    11761 catctacttt agtatcagaa acttttcctt cgcataaaga tttgatatca gataaaaaat
    11821 cgaatgcact acttgccatt ggagagttta actcattgta agtcattgtt ccttcactac
    11881 ataaatttgg tctatttctt atactatcat caatttcttt tttgtcagga tttttcttat
    11941 aataatcatt ataagcagta ctatcttttt tgtaatttgc tcttgcaaac atagtatttc
    12001 tctcatcaac ccttttcaat tctattcccc ctagtaaaaa tatatttaaa aaatataact
    12061 ttattgttgt ataatttaat tatataagaa taacgttata ttttcaattt aagcgtaatt
    12121 aaattgggaa atatataact atatgcttga ttatgatgtt tttattttga aaacaaattt
    12181 aaatacaatc tttttagtga aataaataaa attaaaatat ttttagtatg ataatgcaag
    12241 aaaataatta tttatctaaa aaatctaaag gagagtaaaa ttgaacttat taattattga
    12301 agatgatata aacttaaatg aaggtctttt ttatgcattt gagaatgatg gatttaatgt
    12361 atttaaggct tatacaaaac aagaaggatt aaatatattt aatagtaaaa atatagattt
    12421 tataatctta gactgcaatc ttccagatgg agatggattt gatgtatgtc aaataataag
    12481 ggaaaagtca gatataccaa ttataatgct tactgcaaga gactcagaaa ttgatgaagt
    12541 aaaaggatta gaaatagggc ttgatgatta tattacaaaa ccattttctt tatctgtatt
    12601 aaaggcaaga gtcaaagtag caataagaaa aaaatcgaat aataaagtaa tatattccaa
    12661 tggaataaaa ttggaccaaa agttactaaa agtatataaa aataaagcat gtttggaact
    12721 tagctctgta gaatataagc ttctaagtta tctaattgaa aataaaggtc agatattatt
    12781 aaaggaacaa attttacacc atatttggga cagcgaagaa aattatgttg atgataatat
    12841 tgtatctgta aatataagaa gacttagagt aaaagtagag gatgacccat ctaatccaaa
    12901 atatataaaa acagcttatg gaatgggtta tttatggaat gaggtagaat aatatgttta
    12961 tattagcctt tataatatgt acagttgtta tatttatagt atctactaaa ataaatcaaa
    13021 gaagatatga tgaattaaat ttgatgttaa atcaaatatt ggaaggtaaa gaagttactt
    13081 atccagatac gaaggataca agagcgtcaa aaatttctca ccaagtaaaa aaaattaagg
    13141 atatgataga aatagaggta gaacagtcaa agtcagaaaa agaagcgatt aaaggtttaa
    13201 tatcaaatat gtcacatcaa ttaaaaactc cactttcaaa tataaccatt tattgtgaac
    13261 ttctggagaa tataaatatt tccacattac agaagaagga gtttttacaa aagatgaaaa
    13321 atgaaacttt taagattgac tggttgttac aatccttatt taaaatgact aaattagagg
    13381 atggagttat agaatttgaa gtagaagaac tactaattaa agatactctt attcaaagca
    13441 tcagtactat ctttaataaa tcagaagcta aaaatataag gataaatctc gaaccatttt
    13501 cagatataaa gttagttcat aataaaaagt ggaccataga agcaattgta aatgttttag
    13561 aaaatgcaat aaaatactca ccatcagata gcacgattac tatttctgta ataaaaatgg
    13621 agctatatac gaagattact attaaagatg aaggaatagg tattgatagt agagaactaa
    13681 atgatatttt taaaagattt tacagaagta aaaatgtgga aaaccaaaat ggcacaggga
    13741 ttggtctata tcttacaaga ttaattttag aaaaagaaaa tggaaacatt atagtagaat
    13801 ctaaactagg aagtggatgt tgttttagta tattcttaca gaattgtaag agtttaaact
    13861 aactttgtag gatgagtgta attatcgtca cttacaatat tttatagaac atatatctgt
    13921 attgaaagga gaaattaaat gagtatatta gtgacgaata atttagtgaa acactatgga
    13981 aaaggtgaga ctaaagtaaa agccttaaat ggagtaagta tagaaattga acgagataca
    14041 tttactgcta tagttggaac ttctggttct ggaaaaagca cattgttaaa tattataggt
    14101 ggattagata atccaacctc aggtgatgta ataattaaag gaaagaacat atctaaaata
    14161 ggaaaaaaag atttgacagt atttagaaga agaaatatag gatttatatt tcaaaactac
    14221 agtttaatgc ccgtattaaa cacttatgat aatatagctc ttcctgttac attagataaa
    14281 ggaaaccata tagaccatga atatattgaa atgctgatga agacattggg aatttgggat
    14341 aagcgtttaa aatttccaag cgaactatct ggtggtcaac aacagagggt agcaattgct
    14401 agagctttgg caaataaacc tgcacttata ttagcagatg aaccaacagg aaatctcgat
    14461 agtaaaacta caatggaagt ggtatgttta ttaaaagaaa gtagtgcaaa attccatcaa
    14521 acgatactta tggtaacaca caatgaaaat atagcacaag tatgcgactc aattatccat
    14581 attgaagatg gagttgtggt gaatactggt ggtgaagtac tatgatgtct ctagtaaaat
    14641 tttcaattca atatataaag cattataaaa aacaatctat atctatagtt ttaagcatag
    14701 tactatcagt agcattattg acgggaattg gttctttagt tcatagtgca gacaaaagta
    14761 gaattgaaaa gataagggaa gatagtggag attatcatta tttctataaa gtagataagg
    14821 aacaacttaa taaaattaaa aaaaataaaa aatcaaagga atacattgta gatagacttg
    14881 gcgttacaaa acctaaaaat cagatagatg aaccttttat tatagaattt ttaaatgctg
    14941 attcttcata tttagacatg acaggtagaa aattattaaa aggaactctt cctagtaaag
    15001 atggagagat agtacttgac acatattctc taaacaattt aaatgtaaac aaagaaattg
    15061 gaacagaaat caatttagat ggtaaaatct ataagttatg tggtatttta tcaagtcttt
    15121 caaacccaga aactgctatg gagggatttg taaacgatta tttgcagcct aaagaaaagg
    15181 attcttatat agtttatgta aaatatgatg aaaataaaaa tattaaaaag caaaattata
    15241 aatttatgaa aaaattcaac atatcaaaag aaaaaactta tataaactgg cctctttcag
    15301 ttgaatttgg agtaaaacca ccaaagaata tagaaaaata taatatattt gagttcttaa
    15361 aaaatttaga actaaataca aatgcaatta tattgcttgt tggagtgttt ggtgcagcag
    15421 cagtatatag tattttccat gtttcaatac ttcagagaat atcacaatat ggggttttag
    15481 aagtattagg cgctaataat aaacaacttt tatttctact atttttagag ttatttttac
    15541 tttttattgt tggatttcct ataggttgct tcttaggtat tggagtagcg tctacaatat
    15601 atgaacaatt tccacatata tttttgagta gtgatattgt tccaggagca ttttttataa
    15661 gtgaaaaatc tatttattta ggctttttat ttatcttatt gttgttaatt ttaattgctg
    15721 tacgtgttgt acatcagttg aataaatact ctagtataga atctatgaaa aactttaaga
    15781 ttactaataa gaaaaagaga atattagaaa gtgtaaaaca ctctaacatg acaaaagtat
    15841 tatctcataa atacatgact caaaaaaggg gaatgtttat tggaattttg ttttcattat
    15901 cacttggtgg aattatattt ctatgttcta gttactctat acagcttact aaaaacaata
    15961 atgaacttac aatgaaagct gatgatggtt taaattctga ctaccaaata actatgcaaa
    16021 caacagattt tgatgtaggt ataccaaaag ataaaatttc aagattaaac aatgttgagg
    16081 gaatatcaaa agtctatcca gtaagatatt tatttggagc tatgcaaatt aaagaagaac
    16141 aactattttg gaaaaatttc tttaaacctc ttgaaaaaga ttacaggata aagacttttt
    16201 ttgatggtat ttgtacaaag caaaatgaag gtggctatct tttaaaaaca aatatttatg
    16261 gttataacaa tggtatgtta gaaggattaa attcttatat tatagatggg gagattaata
    16321 cccatgatat ggttaaaaat aataaggtta tagttagact acctatggat ggaactggga
    16381 tgtatgatgc agttgatata aatccaggag atacaataaa agttaaagtg ccaaagacaa
    16441 tgaaaccaac aggtgaaatt gttaaattta aagaagaaaa taagaatgat tatacaacaa
    16501 aagaatttgt agttgctgct actgtaaaac gtgtgatggc aaataacata tatttcattg
    16561 gtgattatgg tatggatata gttatgacga atgggcaaat gaaaaataac tttgatatcg
    16621 aaaattataa ttcagtaagt ataaaaaaga cagaagatag taacagtgag gaattgtctg
    16681 agaacataaa aagtgttgta agtgatgtaa aaagatgtat cgtaacagat tataccattg
    16741 ctattgaaaa aaataatacc tacttaaatc aaaaactctt atttatatat ggtattgtat
    16801 ttgtacttct tgcaataagt ttgttccata taatcaatac agtaagctac ttaatttttt
    16861 caagaagaca tgagtttgga attttaagag ctatgggtat tacggataat aagtttttac
    16921 ttatgatgat aagagaaggt tttttatatg gattctatgc aagtattata atggtaattg
    16981 gaagtgttat tggacaattt atgatttatt ttatggtaaa acgtgtatat ttatatataa
    17041 atccaattct taaaataaat acacctctat acataggtat gattatttta aatatcacta
    17101 ttagtatagt tgctgtaatt attccagtaa gacaaatttt gaagagtgat attatttcag
    17161 aaataaataa gagttagagt tatataaatt tttaagatta tataacttta tgacaatctt
    17221 gtttaaatta tttaaatata tcttatctgt gaacattaaa taaacctctt aatagatata
    17281 actcttgaaa agtcatatct attaagaggt tttaataaat tttcatgtta atatatataa
    17341 tccaaaaaaa ttaaatctta ttaaaacata ctattttgta tagttatcga aatatccttg
    17401 tatgtaaata ataggagtac ccttatctcc acttccagat gttaaatctg ctaaagaacc
    17461 tataaggtct gttaatcttc ttggagtagt accttgagaa accatgtttc ctgttaaatc
    17521 atcagattta ttatcttttt caactatgta ttttgaaatt gcttctttta actcatcacc
    17581 agataagtca gcaaaatcat tatctgctaa gtattttaat tttacttcgt ttggagttcc
    17641 ctctagccct tttgtataag caggagatac tactgggtca gctaattccc atattttacc
    17701 tacagggtct ttaaaagctc catctccata aaccattact tctacatctt tccctgttat
    17761 ttcttttata ttaccttgga ttttgtttac aacttcatcg caatttatag ggaataattt
    17821 tactgtttct tctgtagctt tgtttgaacc taaaagtcca tactggtcat tgtaaccact
    17881 accatctaca cttgctgtca ttatatcatc aagtgaatat acttttttag ctccattttg
    17941 tcttaaaatt ctctttgttc tttgtcttgt atgtatatca caagttaaaa tacttgttgt
    18001 atagttaaga atagtttttg gattgtttgc aaatactatt tctacctctg caccacaatc
    18061 cttgattaaa ttcttataat aatcaacata atctacacca gtaaatgtat gcttgttata
    18121 tccaaatagt tctctgtatt tttcttctgt taaaacatct gaccaaggat ttattccctt
    18181 atcatcaagt tcatcaatac ttattaagtg atttccaact tcatcagaag ggtagcttaa
    18241 cattaatacg acttttctac atccttttgc aattcctttt aaacatatag caaaacgatt
    18301 tctacttaaa attgggaata taaccccaac agtatcatct ccaaatttat cttttacatc
    18361 ttttgcaata ttgtcaacgt gagcataatt tccctgtgct ctagctacaa cagcttctgt
    18421 aacggcaatt acatctttgt ccctaacttc aaagttttca ctttttgacg catttaaaac
    18481 agaatcaaca actattttaa ctaagtcatc tccttgtctt ataataggtg ctctaacccc
    18541 tcttgaaaca gttccaacta atctatccat tatctaaaat cctcctaaag aattaatatt
    18601 gtcatattag taccatgtat attataattc aaatataatt ataagtaaaa taaataatac
    18661 taatatttga cataaggagt aattatatat gaatataaaa cttgaacttt ataaggtttt
    18721 taatgcagtt gtaaataata agagtttttc tcttgctgct aaggaattgt ttatgtcaca
    18781 gccagctgta agccagtcaa taaagcaatt agaagaacaa ttagatactt tattatttta
    18841 tagaaacaat aagggagtaa aattaactcc agaggggaaa attctaagtg aacatgtcac
    18901 tactgcatta aagttgatat catcaggaga agatagaata aataaattta aaaaattaga
    18961 atacggttct ctgaaaatag gagtaggaga tacagctgca cgttttttct tgttaaaata
    19021 tttagaaatt tttcataaga agtatccaca tatacatgta tctacaataa atagaacgag
    19081 tagagaactt atatctttac tcaaagatgg gaatatagat atagcaatta taaacatgcc
    19141 aatagaagat gatacactaa atattgttga gtgtattgaa atacatgata tatttgtatg
    19201 tgcaaatgat tacatagaat acaaaggtag gaaaatatca ttggaagaat taaacacatt
    19261 gcctttaata atgctagaaa ataaagcaaa ttcaagactt tatgtaaatg aatatttttt
    19321 atcaaaaggt ataaaactaa acccggatat agaattgggt tctcatgaat tacttttaga
    19381 atttgcgtat ataaatcttg gagtgtcttg tgttatagaa gaatttagca tagattattt
    19441 ggaaaatgag aaattgttta aattagatat aaaagagcca atacctaaga gaaatatagg
    19501 ttactgccat ttaaaagata tatctttatc cttagcaacc aaagaatttt taagcatgat
    19561 atctaataac atataattta gaatacatat ttcacaagta atttaatata aaaatagaga
    19621 taaattcgta aatttgaaag attcatatag taattagttt ttattaaaaa taaagataag
    19681 gttaatttga gaacatttat ataattaata tcgtatttta aatatgaaca gtatatttag
    19741 attaatgtat aaagggggat tagaaatgtc tgattctgaa tatcctcaaa tgaaaacctt
    19801 agaaactaga agttgtatac taagacctgc atcattagat gatgttgaag atttttttga
    19861 ctgttataaa aataaaatag tagtaaaaca tttaccattt agtgagcata aatctttaga
    19921 agatacaaga aagtttataa aatcattttt tctaaatccc tataaaaaag ggaaaattgg
    19981 ccactttgct atagtatata aaagagacaa taaagttatt gggaatatgg ggtttaataa
    20041 tataaatcct aaagcattag aagcagaaat aggtatatgt ataaatccaa gctattgggg
    20101 acatgatttt gctactgaga taacaaaaag agtaatacag tatggattta gagaactaaa
    20161 cttaaataaa ataattgcaa taacctatga agaaaaccaa aattctacaa aatcattaga
    20221 tttattagga tttaaatgta caggaaagta tatcaaaaaa attcatactg gaaatactgt
    20281 aaaaaatgtt ccttgttatc aatatgaatt gaaaaaacaa tagatataat catttaatat
    20341 ctatcctggt tatttagtaa tgattgtttt ctaaataaaa tttcaataaa gtagttgact
    20401 caaaatatag ataatcctgt tttttattgt taaaatactg aaaatgcatt tgattttata
    20461 caaaaaagag tgtctcatga actaaaaagt ttatgagaca ctctttttga ataaatcgta
    20521 ttttaattaa aatagtatat atacttaaaa tattaatttt tattagttct ctaaattttt
    20581 aaatccttct ccaagaacct catgcacatc tgtaacaata acaaatgcag tagggtcagt
    20641 tcttttaact aatctcttta gataaagttc ttgtttttta gaaactacga ctaatagaac
    20701 ttctttattt tctctagtgt atccaccttt accatcaaga atagtaagac ctctatcaag
    20761 ttcttcagtt atagcttgtc ttaaactttc aggctcatca gagataataa aaaatgcttt
    20821 tgaatggtca aatccttcca ttatcatatc tgctattttt attaatacac aaagtgctat
    20881 accagagtaa agagcagttt ctaaactacg atttactata ccagaagata taacaaccat
    20941 tccatctagg catgacatga attttgtagc ttttattcct gggaatttct tactaagtat
    21001 gagtgcaatt aagtctgttc ctccagtaga agcatctgat ttaaacatta ttcctaaacc
    21061 tataccaact aggattcctc ctgcaataga agacaataat aagtcattag taaatcttag
    21121 ttttgataat gggtctgtta attgaactat agctgaaaat acaactgttc caaataaagt
    21181 ttttaatgaa ttttttgtac ccataattct aaaagcaagt attactaatg ggacacctat
    21241 aattaacatg atagctgata ctggaagtcc tgtaaccttg tttagtacta atgatagacc
    21301 actaagtcct ccaggagcaa ttgtatgtgg ttttaaaaac atatttatac caatactcat
    21361 tgatatacaa cccaaaaata gtccaagcat ttcaagtaaa attggcgact tttgtttttt
    21421 catataaaca cctccatgaa cttgtcacaa tttaatatta taacatattt gaccagttta
    21481 tattatataa aatttcttga tataagcaat ttcaagtatt tcattattct taatattttt
    21541 gaatttttat atagtgtttt catatcttta ctgatgttgt tacactccta tgaagttttt
    21601 tatatattat aattttttta ttcttttata aagtatcccc tataaagatg gttctatgaa
    21661 aattttctct atactgttta acgtatatag agattttgtg tataattata aggtatttaa
    21721 tggaaaaaat tatcttgctt ttatatgtta tcaaaaggat ttattaaata caacagacag
    21781 cttgataaca tataattata taaatataat ttatgtagat agttgtattt ttaaataaat
    21841 ttttacatat caataattat tatctatttt atataagcaa caatcaaact aaaataaaag
    21901 tttaagaaaa gagttgatta aatgcataaa cctagttata aaacagtatt tcattcatac
    21961 attatttttt tcatgatttt tatttgctta atcctgacag taataggtat tttcttatca
    22021 cttattacta ttcagaaacc aaatggggaa tttattcgta gtgactggcc gaaaaaattt
    22081 acagaaaact ttaatgaaca aatcatattt atagataata agccacaagt aaaacagtct
    22141 ggattagaaa agcttcgaga aaatcaattg tggttgcaaa ttttagattc tagtggaaat
    22201 agagtttatg ggtttttaga accaaaagag cataaagatt attattctaa ttctgaatta
    22261 ttaacattag ctaaccaaaa taattcaagt aatggaactg tatactttaa tacaattaaa
    22321 aataataaaa atgactatat ttatattata tattttccat taaatatatc taaagtgaat
    22381 atgttttttg atggaagtaa atttgtaggt ggtaagtcaa ttgtattttc aatcataggg
    22441 attatatttt taataatttt gatttctgga attgcttatg gttactgggt aacaaagtgc
    22501 atatcaaata ttacatctgc tgttagtgat atttcaaaac gaagctatct tccagttaat
    22561 attaaaggtg tttttgctga tatatataat agtttaaata ttttaaatga agaaattcat
    22621 agaagtgatg agatacaaaa taaaactgat attatgagag aagagtggat ttcaaatata
    22681 actcatgatt taaaaactcc actttcacca ataaaagggt atgcagagct tcttacagat
    22741 agtagtacta attattcacc tgaaaaagta tataaatatg cttcaatcat gttaaagaat
    22801 atagaatata caaatacact tataaacgat ttaaaattaa cctatcaatt aaaaaatgga
    22861 ataattcctt taaataaaaa taaatatgat ttagtaagat tcttgaaaga attatccatt
    22921 gatattttaa attatccaga atatgaatca aatatagttg aatttaagag taatatagat
    22981 aatattaact ttgattttga ttgtacacta ttaaaacgag cttttagtaa tcttattgtc
    23041 aatgctttta catatggaga taaaaatact aaagtttgtg tacatataac attaaatgaa
    23101 agaattgaaa tcattatatc tgataatgga aaagggatgt caagagaaga agcatcaaat
    23161 ttgtttaatc gttattatag aggaagcaat acaaaacaaa aaatagaagg aactggttta
    23221 ggactagcaa taacgaagca aattattgaa gttcatggag ggaatatatc tgttgaaagt
    23281 atacctggat taggtagctc attttatatc acctttccta tttaattaag gttaattaag
    23341 gtcaaataaa aaatatatta aggttgatag attattatat ttatatagta gtttatcaat
    23401 cttttttatt taaggaggtg atttgattaa aaatattata aatagaatga taaaagtatg
    23461 gaggagtcta ttagagattc aatttggatt aaagtataaa aatattatac tgaaatatct
    23521 tagataaagg aagaaggtgt aaatttgaaa attatattaa agtatatttt cacaaatatt
    23581 aaagaacgaa aaattagaac agcagttatg ttactgtcca tagttttatc aacagtttta
    23641 ctttttgttt cattctcaat tggattatct tatgaaagtg cacaaagaaa aatggcaaaa
    23701 ggtatgtatg gtacagcgac tatatctgtc caaagtaaaa atccagatgt attaaccaat
    23761 ttagaagaca tacctgattt aaatgctata aaatcaaagg ttggtgtatt ggaaagctct
    23821 gctatttata ataaaggggg atactatgaa gaatttagtc ttatatcagc agacttaagt
    23881 caactaaata aaatcaacaa gccacgatta gaaaatggcg atagtattac tgatttttct
    23941 ggtgataaaa ttattcttcc aaatcgcttt acatcaaaat ataaaataaa aaaaggtgat
    24001 tctattactt tacagattta tggaaagtct tatacttttc aagttagtga tattgcatct
    24061 tatgatacag tatttttgag gaatacaaga ggtgtaaatg cactgctacc caaagagact
    24121 ctatcaaaaa ttataaataa aggcagtgga tatacaagag ttcttataga gtcagaagaa
    24181 gaaatgacag aaaatctagt aaataaatta tccgaagaac tttccactga aaaatatatg
    24241 gtatcaaata ctataaatga aactaagata atttcagatg ctagacaaaa gacaatgcct
    24301 ttctttttaa taagtttttt tgcattaacc cttagtatat ttatcatata cagcagctat
    24361 aaggttatta cattagaacg tcttcctttt attggaacat ttagaagtat tggtgccaat
    24421 gaaaaaactg taactcgtat attgatgctt gaaagtatat tatacggaag tataggagga
    24481 ttaattgcta ttcctattgg tgtagttgtt ttaaatttaa tgcttcatgg gttaggaaat
    24541 tctctcgaac aaggaatatc aattccagta gtaatatcac ccattggagt gattatatct
    24601 gttatagtag caataatcgt ttcttcattt agtgcatata tacctgttaa aaaagctagc
    24661 catttgccaa taaaaaatat tgtactagga acagtagaag aaaagaatgt ttcaaatcgt
    24721 tctatacttt ttataggaag tataatgttt attttatcta ttttacttcc aagaatatcc
    24781 cctgaaaata cattgtatct agctggtgga ttttcattac taggattaat tgtagctact
    24841 attgtgttga ttcctcttat tactgatatc atgtctatag tttttgagtt tgtttataaa
    24901 aatattttag ggaatgaggg taaattagct gctagaaata tgaaaaataa caaaaatata
    24961 atacagaata tcactttact atttataagt atttctgcag ttattgcaat aagtgttgtt
    25021 ggtaactttg tcaaaactta tataacagat gtgtttcgtg acgcagaatt acaaggtttt
    25081 gcagatggaa agatgaatga agagtttatt gaaaatgtta gacatatgga tggaattaaa
    25141 aaaatattac ctctttatgt tatgaataat gagatttctg gtaatggtgt aacattatca
    25201 agactagagg gtacagataa tataaaacta tataactcta tgtttggaat caattataca
    25261 aattttgaga taaaaaaaca agtaatagaa gcttttaatg ataaacgttc tgttattttg
    25321 aatgaagata ctctaaaaaa agtaggctta tctataggag atacaataac tctatctaat
    25381 gataagtatg atttttctta taaaatagta ggtagtttta aatcccgtgc aaatgatgta
    25441 gaagctgtta taccatcaca ttatgcagtt aatgattttg ataaaactaa ttatggtttt
    25501 ttagtatata cagcagtcaa tccagatgtt gttatgattc agataagaga tttatttgga
    25561 gatacatata attggagtcg tacagttgaa gaatttaata atgattcttt aaatactata
    25621 agtagttttt tgtctcctat gaataagatg acctatttca tttttcttct tgctacagta
    25681 ggtattatta ataatctact gattaattat attcaaaaaa aacgttctat agctatgtat
    25741 aaatctatag gactaagtga taaacaaaat ataaaagtga cattgattga agggtttact
    25801 tcaggtttac ttggagctgt tattggtatt gtgatatcta tacttgagat tcaaactatc
    25861 tttatagttg caggaccaaa aatttcaatg aaaccagatt tagattttaa aacatttatt
    25921 attgttgggt tattgggaat tatagtaact ttaataggtt cgatagtgcc tattataaaa
    25981 gggaagaaaa tgaaactgat agaagaaatt aagtttgaat aattatggag gttaatatga
    26041 aaattacaca taatagttta gctgtagaag caaaaaatat tatcaaagaa tataaaattg
    26101 gaaatacaac aactcgagtg ttaaaagagg tatctttaca agtaatgaaa ggtgaatttg
    26161 tttctatcat gggtcaatct ggttctggta aaagtactct tttatatatt ttaggtggtt
    26221 tagatactcc aacgagtgga aaagtgtata tgaatggagc tgatatatca cattttaatg
    26281 atgagaaaat gagcataata cgtcgtagaa atataggatt cgtatttcaa ttttataact
    26341 taataccaaa tttaaatgtg gaggaaaata taatgcttcc tttgttatta gatggtaaaa
    26401 atttaaaaga ttataaaaat caattagatg aaatcttaga tatagttggt ttaactgata
    26461 gacgtaaaca tacaccacga gagttatctg gtggtcagca acaacgtgtt gctatagctc
    26521 gagctttagt tggaaaacca gagattttat ttgctgatga gcctactgga aatttagata
    26581 gtaaaacagg gatagaaata atagatttac tgaataaaat aaacagagac aatggacaaa
    26641 ctataattat ggtaactcac tcaccagaag cagccaaaag tagtagtcgt actattacag
    26701 tttcagatgg tttaattgta taaggactaa ttattgtatt tgagataagc atttttaact
    26761 atataaatta gacatatgta aagtggatat aagttaaata ctataaatgt gctataatat
    26821 taaaataaca gataaaagta ctatattttt tattgattat tttaatttat ttgtttatta
    26881 aatatctaat gagtattcat actatctcta ttattaaaag cagttaatga tatatagaga
    26941 taatatggat tcttcttact ttaataaata ttcacgatag gacaggatat aatatatgtt
    27001 aaaaaaagaa agtattcatt ttataaataa aaataggtca cttatagttt gtgaagacaa
    27061 ttttgtttat ctcttgcctt gtatgcaatt aaaaaattgg atatcgaatt ttactatatc
    27121 gtttccaaat caaacaataa tttctgataa ttacacgatt attcctcatg gaagtgtaac
    27181 tttggtgttt ttttatgatg ccacagggtt acatagtcta ttatttggtc caactactaa
    27241 accaaaaaca gtaggaaata ttgctaatag atgtgatgtt atactaatta tagaatttca
    27301 acctgctggt tttttcccgc ttataggtat acagcaaagt gaacttattg ataaagttgt
    27361 tccattttct ataattaata cttcattaga tttagaaatt aaaaaaatat ttaatgaatc
    27421 tttatctata gataaattga ttttaaagtt ggaagaatta ttgatttcta atattaaaat
    27481 tgaatactca tatgagttta ttttggcaat tcagttgatt attcaaaact ctggaaacat
    27541 atcttcacaa gaaatttcta aaaaagtatt ttatagttct aggcatttaa acagactctt
    27601 taatcagtac ctagggttga gtatgaagtc attttctcgt ttggtacgta ttaataaatc
    27661 tataaaactt ctaaacaata ataaaacttc attgatgtat atatgtaatg aattaggatt
    27721 ctatgatata ccacatttta ttaaagattt taaaattgtc tgtggaataa ctcctcaaaa
    27781 ataccgagct aatatgtctg atttttacag tgaaattgca aaattttaag ttataatact
    27841 tataacaaag aaaggatagt gataagatga aatttggagg agtattgcta attgtcaaag
    27901 acataaataa atcaaaaaag ttttatgaag atgttatgga gcaaaaaatt acattagatt
    27961 taggagaaca tgtatcattt gaaaatggat ttggattaca aagtaattat aaagctataa
    28021 ttggatatga tttaccaata tatcaacaat caaataactt tcagttgtat tttgaggtta
    28081 atgatatcaa acaatgggaa agtaagataa atagaatagg aaatattgaa tttttgcatt
    28141 atataaaaga atacccatgg ggtcaaagaa cttttaggtt ttatgatttt gataaaaata
    28201 ttatagaaat ttcagaaagt atggaaagcg tcataaagag gcttttaaaa caaggtttag
    28261 ctttagaaga aatttcaaaa cgcactatgt atccagttga atttattaca caatttcaac
    28321 aattataaaa tattaaaata tataattttt tctttatatt gcaaaaaaca aaggcttggg
    28381 gcataataga aaaatacttg aaataaatta catacttaat gtttgaattt agcttaaaaa
    28441 tgaaaagacg aagaaattta tacttggagg taattacgtt atgcatgatg aactgaaaat
    28501 caaaatgtac tcatttacga tggattgcaa agacccacat gaattagcaa aattttatgc
    28561 agcgttactc aattgggaaa tagcatttta taatgaagaa tatgcatgtg ttggtgctcc
    28621 aggaacaaat cagggaacat atcctggtat aacatttcaa cgaaattctg agtataaacc
    28681 gcctgtgtgg ccagaaaaac ctgaatctca acagcaaatg gctcatatgg atttcgctgt
    28741 taatgattta gaagaagcag ttcaatatga aattcattgt ggagctacaa tcgcagagga
    28801 gcaatttact gatgactgga gagttatgat tgacccagct ggacaccctt tttgcttatg
    28861 tcagatgaaa tcaattatgg aaagtagcca tttttcattg ttatagacca aaatattgtt
    28921 tattaattac aaaaaagcac aacagtatat accgttgtgc ttttacttat tatacatgaa
    28981 tacactaaaa aatataaata gtagagcttt atcaataatg ataattttta aaaaatagta
    29041 tttttttatt gaataatttc tt
//
LOCUS       DAMJYN010000046        28344 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.047, whole genome shotgun sequence.
ACCESSION   DAMJYN010000046 DAMJYN010000000
VERSION     DAMJYN010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 28344)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28344)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28344
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.047"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(274..345)
                     /locus_tag="PC466_002212"
     CDS             complement(274..345)
                     /locus_tag="PC466_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HDF2769594.1"
                     /translation="MLEILVHITTTVISGCIIALFTH"
     gene            complement(777..2276)
                     /gene="mqo"
                     /locus_tag="PC466_002213"
     CDS             complement(777..2276)
                     /gene="mqo"
                     /locus_tag="PC466_002213"
                     /EC_number="1.1.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019835172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malate dehydrogenase (quinone)"
                     /protein_id="HDF2769595.1"
                     /translation="MNTKESKTVVVIGAGVLSTTFSSMLKELEPSWNIKLYERLDRPG
                     IESSNERHNAGTGHAALCELNYTVKQPDGSIDIEKAKEINEQFEISKQFWGHLVKNNS
                     ISNPKEFIQPLPHISFVRGKNNVQFLKDRYHAMKDFPMFDNIEYTEDIEEMRKWVPLM
                     MEGHSSSDIMAASKINEGTDVNFGELTRKMAKNIEQHPNANVQYNHEVIDFNHRKDGK
                     WEIKVRQRNSGDVQTELADYVFIGAGGGAIPLLQKTGIPESKHLGGFPITGQFLICTN
                     PDIIAQHDAKVYGKEPPGTPPMTVPHLDTRYIDGERTLLFGPFASVGPKFLKNGSNLD
                     LFKSVKPYNITTLLSAAAKNLPLIKYSFDQILMTKEGCMNHLRTFYPEARDEDWQLYT
                     AGKRVQVIKDTPEYGKGFIQFGTEVVNSEDHSVIALLGESPGASTSVSVALEVLEKNF
                     PEYESEWMPKIQKMIPSYGKSLINDTALMKKIRQQTSKDLELNYYQSNK"
     gene            complement(2409..4013)
                     /locus_tag="PC466_002214"
     CDS             complement(2409..4013)
                     /locus_tag="PC466_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019236163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate permease"
                     /protein_id="HDF2769596.1"
                     /translation="MLVHSFDPFHNLLLSSIVAAIPIILFLLCLTVFKMKGVYAALTT
                     LIITILVALLVFKLPLNIAGGATFEGFYQGIIPIGFIVIMAVWLYKISTKSGQFDIVK
                     DSIASISQDQRIQLLLIGFVFNAFLEGAAGFGVPIAICAVLLTQLGFKPLEAAMYCLV
                     GNAAAGAYGAVGIPVAIIDTLNLSGDVSATEVALIGNLTLGFISFFVPFLLIFMIDGF
                     RGIKEILPSILVVSVTYTFLQVIITSFAGPELADIIPGLAAMVALALFSSKFQPKNIF
                     RLQQNEEPKRVTKHSFKNIVYAWSPFIILTVIVLIWSSSFFKGLFEKKGLLHSLVINF
                     NVPGTMNDVTHAPNVLTFNFIAQTGTAILITAILTIIIANNMNFKIAGKLLGLTVKEL
                     WISVLTICFILAVSKVTTYGGLSSAMGQGIAKAGSIFPLLSPVLGWIGVFMTGSVVNN
                     NALFAPIQASVAGQIGAKGSLLVAANVAGGVTAKIVSPQSIAIATAAVNEVGNESQLM
                     KMTMRFSIALLVFVCIWTFLLSLLIS"
     gene            complement(4048..4752)
                     /gene="budA"
                     /locus_tag="PC466_002215"
     CDS             complement(4048..4752)
                     /gene="budA"
                     /locus_tag="PC466_002215"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HDF2769597.1"
                     /translation="MTNILYQHGTLGTLMAGLLKGTASINELLEHGDLGIATLTGSNG
                     EVIFVDGKAYHANEYKEFVELKGDELTPYATVTKFTADTTYQTKDKTSEAVFDEIKEK
                     MLSENLFSAVKISGVFKKMHVRMMPGQEPPYTRLIDSARRQPEQTETYVEGTVVGFFT
                     PELFHGIGSSGFHIHFANDDRNFGGHVLDFEIEDAKVEIQNFETFEQHFPINDEIFNK
                     TDIDYKDISEEIREAE"
     gene            complement(4785..6449)
                     /gene="alsS"
                     /locus_tag="PC466_002216"
     CDS             complement(4785..6449)
                     /gene="alsS"
                     /locus_tag="PC466_002216"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011274786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase AlsS"
                     /protein_id="HDF2769598.1"
                     /translation="MTNKNYNAANIVIDTLKNNGVEYIFGIPGAKIDYLFNALEDDGP
                     ELIVTRHEQNAAMMAQGIGRLTGKPGVALVTSGPGVSNLTTGLLTATSEGDPVLALGG
                     QVKRNDLLRLTHQSIDNAALLKYSTKYSEEVQDPESLSEVMTNAMRTATSGKNGASFI
                     SIPQDVISAPVESKAIALCQKPNLGVPSEQDINDVIDAIKNAAFPVLLAGMRSSSANE
                     TNAIHKLVEKTNLPVVETFQGAGVISRDLENHFFGRVGLFRNQVGDELLRKSDLVVTI
                     GYDPIEYEASNWNKELDTKVINIDEVPAEITNYMQPTKELIGNIAGTIEMISDKVDEP
                     FINQQHLDELEQLRAHIVEETGIKATHKDGVLHPIEIIESMQKMLTDDTTVTVDVGSH
                     YIWMARKFRSYNPRHLLFSNGMQTLGVALPWAISAALVRPNTQVVSVAGDGGFLFSAQ
                     DLETAVRKNLNIIQLIWNDGKYNMVKFQEEMKYERSSGVDFGSVDYVKYAEAFGAKGM
                     RVTNQEELEHAIKKGYEIQGPVVIDIPVNYKDNVKLSTNMLPDAFN"
     gene            complement(6720..7394)
                     /locus_tag="PC466_002217"
     CDS             complement(6720..7394)
                     /locus_tag="PC466_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HDF2769599.1"
                     /translation="MNYFRYKQFDKDVITVAVGYYLRYALSYRDISEILRERGVNVHH
                     STVYRWVQEYAPILYQIWKKKNNKAYYKWRIDETYIKIKGKWCYLYRAIDADGHTLDI
                     WLRKKRDNQSAYAFIKRLIKQFGKPQTIITDQAPSMKVAMSKLRKDFKLKSNCHCTSK
                     YLNNLIEQDHRHIKVKKTSYRSINTAKNTLKGIECIYGLYKRNRRSLQIYGFSPCHEI
                     SYMLVS"
     gene            7757..7858
                     /locus_tag="PC466_002218"
     CDS             7757..7858
                     /locus_tag="PC466_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HDF2769600.1"
                     /translation="MVEALVHITTTVISGCIVALFTHWLRTCNNKKK"
     gene            complement(8155..8820)
                     /locus_tag="PC466_002219"
     CDS             complement(8155..8820)
                     /locus_tag="PC466_002219"
                     /inference="COORDINATES: protein motif:HMM:NF015431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769601.1"
                     /translation="MSLTSDGEKLFQYALQRERLEQTLRHDLKMQPDTISGDVTVGSS
                     YTYGEYRLSQHLTDLAKKYPELYIHVYLNNSDTVLQHIKNNTIDLGIIEKEVQSNIIH
                     SRRIAQDEIVLIRKKSSSSNKSICFIRERGSGTRVYQENALSQMTSSSYLVEINNTNL
                     IKNMVHADKGFSIVSKSTLTPYDLEKLEVTNLDITRYFYLVIHKDKYIDTKLNEVIKN
                     LVS"
     gene            complement(8797..8889)
                     /locus_tag="PC466_002220"
                     /pseudo
     CDS             complement(8797..8889)
                     /locus_tag="PC466_002220"
                     /inference="COORDINATES: protein motif:HMM:NF012354.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
     gene            9100..10095
                     /locus_tag="PC466_002221"
     CDS             9100..10095
                     /locus_tag="PC466_002221"
                     /inference="COORDINATES: protein motif:HMM:NF015558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family protein"
                     /protein_id="HDF2769602.1"
                     /translation="MKSLKSKAFIYGLLFTFIIAVISLLGSKLPFLDKIGALTIAILI
                     AILYRHFKGYPEAYRSGIAFSSKRLLKLAIILYGLKLNIYDVIGKGSDLLLIDIGVIL
                     FSIGLMLLLNKYIKGDKNLILLLGIGTGVCGAAAIAAVSPILKSREKDSAISIGIVAL
                     IGTIFSLAYTVIYSVFTISPEVFGVWSGTSLHEIAHVILASGFSGQEALSMGLLGKLG
                     RVFLLIPLSIILILIMRKKSHSENEKKRIDVPYFLLGFVMMALFHTYVSLPHMVMQII
                     DNITTICLLMAMVALGLNVSFKDLKDRAFKPLIVVIIVSICLSTVTFIVAKYFYS"
     gene            10621..11193
                     /locus_tag="PC466_002222"
     CDS             10621..11193
                     /locus_tag="PC466_002222"
                     /inference="COORDINATES: protein
                     motif:HMM:NF012655.1,HMM:NF028235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2769603.1"
                     /translation="MSKKLEILTIAREVIHSKGYKATSISDILNAADIGKGQFYYYFS
                     SKRDLGLAVIDDLVEDWTEQLINSKLHNSENPKENLNAMLDWSFKYHDDMSSKAGCPV
                     GNLAIEMSEHDDLFREKIQAFIDKWILSMKENLDGLKAQEFIGNLDTEKHAQTIFSTI
                     EGAIMLTKVKQDVEYLKNVIEIIRWQYNLT"
     gene            11307..12260
                     /gene="trxB"
                     /locus_tag="PC466_002223"
     CDS             11307..12260
                     /gene="trxB"
                     /locus_tag="PC466_002223"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014093692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HDF2769604.1"
                     /translation="MAEQVDFDVAIIGAGPAGMTAAVYASRANLSTVMIERGMPGGQM
                     ANTEEVENFPGFEMVTGPDLSTKMFEHAKKFGAQYQYGDIKSIEDKGGYKVINLGNKE
                     ITARAVIISTGAEYKKIGVPGEQDLGGRGVSYCAVCDGAFFKGKKLFVIGGGDSAVEE
                     GTFLTKFADSVTIVHRRDELRAQKILQDRAFKNDKIDFIWSHTLKTINDKDGKVGSVT
                     LESTKDGSEQTLDADGVFIYIGMKPLTTPFLDLGITNDVGYIETNEDMSTKVPGIYAA
                     GDVRDKGLRQIVTATGDGSIAAQSAIAYIEHLNDNSEILSI"
     gene            12469..13128
                     /locus_tag="PC466_002224"
     CDS             12469..13128
                     /locus_tag="PC466_002224"
                     /inference="COORDINATES: protein motif:HMM:NF014664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HDF2769605.1"
                     /translation="MLQNDSLYKRSDTKRLVEFTKLSHDSFKSFMEFYHQVLSEGHLS
                     KKFKEVISIAVAHTTGCAHCIDHHVKQFKKLGGTKEEMAESIMVATALKAGSAMAHSV
                     NALNAYDEIEDDELYKASYFNRLKELGQLDGERFKAFINFDQQAMKAGLLTVKEKELI
                     AIAVAHTTGCPYCIDIHTKSAKKAKVTKEEVAEAILVATLLKAGSAMSHGVNALNAYD
                     E"
     gene            13224..14234
                     /locus_tag="PC466_002225"
     CDS             13224..14234
                     /locus_tag="PC466_002225"
                     /inference="COORDINATES: protein motif:HMM:NF012927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="12-oxophytodienoate reductase"
                     /protein_id="HDF2769606.1"
                     /translation="MNLKNRIVMAPMTRNASPNGIPGQNVRDYYTRRAENNVSLIITE
                     GTFINHPDVASEVPAWQHDVPHMYGELALKGWADIVNSVHNAGGKIFSQLWHMGGRGN
                     VDDYTIQEINGLIDAYVEGALNAQKVGFDDIELLAGHGFLIDQFFWERTNHRTDNYGG
                     SLAKRSTFASELVGSIRRAVGPNFPISFRISQWKYNFYQEKLANNPEELETFIKPISE
                     AGVDIFHGSTRRFWEAEFKNSELNLSGWIKKVTGKPTITIGSISLEGSDFINYFDEGR
                     EAEHNTNKMTGLVRKLENGEFDLVAVGRAILVDPEWAMKIKKGKVNELKSFTKDAQEK
                     LY"
     gene            14267..14770
                     /locus_tag="PC466_002226"
     CDS             14267..14770
                     /locus_tag="PC466_002226"
                     /inference="COORDINATES: protein motif:HMM:NF014608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OsmC family protein"
                     /protein_id="HDF2769607.1"
                     /translation="MNGINMNIIEELAKEYSQEPQKGIQPYKANINWNNGLSAVAKVG
                     NHDELLIDEPEWLAGTNKGPNPVEYLLSALGGCLSLSFILSANNKNHEIKGLDVEVTG
                     DVDLNILLGLKEGNPGVYNLNVTFNVDTEIEDVKIEELMHDALSISVVGNTVQSKVQI
                     NPEYKRK"
     gene            14829..15143
                     /gene="trxA"
                     /locus_tag="PC466_002227"
     CDS             14829..15143
                     /gene="trxA"
                     /locus_tag="PC466_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020808024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HDF2769608.1"
                     /translation="MATITVTEKTFNKTIEKGVTLVDFWATWCPPCQMQSPVLEELSD
                     ELEGKVIIGKVDVDEEKALAAKYQIQSIPTLLIFKDGELVNTLIGFNPKPNLENALTK
                     YL"
     gene            15243..15524
                     /locus_tag="PC466_002228"
     CDS             15243..15524
                     /locus_tag="PC466_002228"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HDF2769609.1"
                     /translation="MNTQEKLMLYVMAENCNVCHADFPKVDVLAKKHNVDSVNIMINE
                     IPEAAGQLSLFTAPVVILFYKNKEMHRQARIIDFEELEYRIKQLNEIES"
     gene            complement(16010..16558)
                     /locus_tag="PC466_002229"
     CDS             complement(16010..16558)
                     /locus_tag="PC466_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDF2769610.1"
                     /translation="MAKIGYARVSTQDQSLDGQIDTLEEYGCERIFSEKASGRKTKRT
                     ELDKCLDYLREGDILVIYKLDRLGRTTKQLIELSQWFDENSIDLHIIDMNVSTKDAMG
                     KMFFTMMSAFAELEANLLSERTKKGLEAARARGRKGGRPSLPDHKKREIKFLYDEQKL
                     TGEEIAKQTGVSRSTVYRMLKD"
     gene            16811..17494
                     /locus_tag="PC466_002230"
     CDS             16811..17494
                     /locus_tag="PC466_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017723716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase
                     domain-containing protein"
                     /protein_id="HDF2769611.1"
                     /translation="MKKSLIVVTNIAKYDNLERPTGAWFSEVTHFAKDFYDAGYEVDF
                     VSPNGGYVPLDPVSLSPEMMSTEDWKYYTNHEYMNKFGQTLSPKEVNPNDYQAIYFAG
                     GHGAIWDLRNNKELNDIALSIYNNQGVLSSVCHGAVGLLDIKENGDYLVHHKDVTGFT
                     NSEEQANGTTEYMPYLLEDEFISNGAHFKKEDDWSNFAVVDGRIVTGQNPQSGHAVAE
                     HALKILANQ"
     gene            17516..18180
                     /locus_tag="PC466_002231"
                     /pseudo
     CDS             17516..18180
                     /locus_tag="PC466_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002488150.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
     gene            18184..19188
                     /locus_tag="PC466_002232"
     CDS             18184..19188
                     /locus_tag="PC466_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001826295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="HDF2769612.1"
                     /translation="MNNQQVVLAKRPQSIPQDDVFRFETIETREPHAGEVQVESIYVS
                     VDPYMRGRMNDTKSYVQPFQVNEPLQGHIVGKVTQSNDERLSVGDYVTGILPWKKINT
                     VNGDDVTPVPSKDVPLHLYLSVLGMPGMTAYTGLLQIGQPQSGETVVVSAASGAVGSV
                     VGQIAKIKGAKVVGIAGGKQKTTYLTDELGFDAAIDYKQDDFAQQLEAAVPDGIDVYF
                     ENVGGVISDEVFKHLNRFARVPVCGAISAYNNEKDDIGPRIQGTLIKNQALMQGFVVA
                     QFADHFKEASEQLAQWVSEGKIKFEVTIDEGFDNLPSAFRKLFTGENFGKQVVKVAEE
                     "
     gene            19198..19563
                     /locus_tag="PC466_002233"
     CDS             19198..19563
                     /locus_tag="PC466_002233"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769613.1"
                     /translation="MKNIIVRFIFSLMFYKSGVAHFKNKDMFLKIVPSYLPFKHAIVK
                     YSGILEFIIAFYVLGAKNRSRVRKVVQGFLWLVFPANIYAARKNISYKDERDETDSVK
                     QHVIRLPLQFVMLALAKLL"
     gene            19879..20263
                     /locus_tag="PC466_002234"
                     /pseudo
     CDS             19879..20263
                     /locus_tag="PC466_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002455937.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            20710..22209
                     /locus_tag="PC466_002235"
     CDS             20710..22209
                     /locus_tag="PC466_002235"
                     /inference="COORDINATES: protein motif:HMM:NF017206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-binding protein"
                     /protein_id="HDF2769614.1"
                     /translation="MKKILLTGASGYIGSHLMNKLKDNYEIIAISRNIENKSNEQNVT
                     WKAADLFDLNEITEVMEDIDIAIYLVHSMMPSAKLTQASFEDMDALLADNFAKAASYN
                     KVQHIVFMSGLIPNTNELSPHLRSRLECEQILGSYGVPVSTLRAGLIIGSKGSSYPIL
                     KKLVERLPGLLLPKWAYNITLPVAIDDVIDGLYKIVERNPNENESIDIGGPSHMTYKD
                     LFKQTAEVLDKRLPTIDLPIIPIWLSKYWVKLISGVPKEMVYPLMDSLIHDMIRNDEN
                     IVKDISIGKIDYKESVRNALEEETKTQKKGKSSRKGDIKDVRAISRVVLPKDVNMIQL
                     AESYANFLNRITLNVVNSDFNEDNFTISVPCLNKDLLLLRKDFKASNNERILYRIVGG
                     DFASDSDGGNARLEFRRLPNSDACIIALQEYEPTLPWWVYKYTQAKVHKSVMNLFKFK
                     INSQKTNKGEYFNMKKFILPIVITGAIVLKVYGVKKYLARKNNMSNAEL"
     gene            22259..22759
                     /locus_tag="PC466_002236"
     CDS             22259..22759
                     /locus_tag="PC466_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017636318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="HDF2769615.1"
                     /translation="MKANEIIKTIIKVITPITGGKFIGKFAVKNARKDYKNNVKPLFS
                     PPGYVFPIVWPILYTTMGVSYALVTNKSTSKALKGAYYSQLSLNYLWSILYFKYKLRF
                     SALIESVVLLGAVVTTTVKFFNVKKVAGILLVPYMLWSAFATYLTAGNWYLNKDNPSY
                     TAKSEH"
     gene            22764..23237
                     /locus_tag="PC466_002237"
     CDS             22764..23237
                     /locus_tag="PC466_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017723074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl-4,4'-diaponeurosporenoate
                     acyltransferase"
                     /protein_id="HDF2769616.1"
                     /translation="MKKIIYIALYWFIVQMIIAQLGTRISYKFLEKDNKYFRSWNIEQ
                     EGQLWQQLVKVQYWKDHLPDGQNLNPNISSKATFDLSKNMNDIQRFILETRRAEVVHL
                     LSIFPVIAFFKASKSVKIINFIYVIIANVPCMIVQRYNRPKLIRMYNKLQIRKGD"
     gene            23238..24728
                     /locus_tag="PC466_002238"
     CDS             23238..24728
                     /locus_tag="PC466_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019469195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDF2769617.1"
                     /translation="MGNKKVVVIGGGLGGIASAICMAQAGYQVDLYEQNKHIGGKVNR
                     LDIDDYGFDLGPSILTMPKVFQRLFQRCDERLEDYVSIRKLSLQIRNVYPDGQILDLY
                     ESMEDMLTNNESLTNKDIEQLSSFFSYAQKIHQVAEKSYFDKGLDTMFAIIRYHGPFS
                     ALKQFDYFHTMQQAINKRVDNPYLREMLGYFIKYVGSSSYDAPAVLSLLPQMQHEEGL
                     WYVDGGIHKLAEAMEQLARKLGVGIHFNTPVKRINYNSQNKVTGITIESNKEIYADYI
                     ISNMEVIPVYKYLLNFDANQINKLERKFEPASSGYVMHLGVDKSYPELQHHNFFFSSN
                     SKVNYDQVFHQYVLPEDPTIYVVNTNKTDKTQAPEGHENIKILPHIPYIQSKSFSEAE
                     YLQFQERILDKLESMGLKDLRKHIVYEDVWTPHDIENTYNSNKGAIYGVVSNKKKNKG
                     FKFPKKSQYFKNLYFVGGSVNPGAGMPMVTLSGMQVAEAIINGESS"
     gene            24795..25838
                     /locus_tag="PC466_002239"
     CDS             24795..25838
                     /locus_tag="PC466_002239"
                     /inference="COORDINATES: protein motif:HMM:NF012745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDF2769618.1"
                     /translation="MYARRAIINNSGKGRGQTALSIIVPARNEAENLPKLLNSISKKQ
                     EIEVIVMDDGSTDETQVVARYYGASVYTVENDTTWQGKSHACWQGSKYATHDLLMFVD
                     ADVQFACDDSIQNIANQYDLLGGKGLLSIQPYHKIKKLYENISAIFNLMTIVGMNQFS
                     ITKSANNEQGAFGPVLVTNKQDYKLTQGHLKAKNQIIEGFAISKAYNQQGLPVSLHEG
                     QGVVNFRMYSQGYKSLLEGWSKHFALGSQVTKKSTLTFVFLWLFGSLTTVLAIIFSIN
                     LGSLYILLAITLYFIYAIQFHIFIRRTGNFNIVASLCHPLLFICFVVIFFKSWLDINV
                     FKRIYWKGRRIDL"
     gene            26009..26722
                     /locus_tag="PC466_002240"
     CDS             26009..26722
                     /locus_tag="PC466_002240"
                     /inference="COORDINATES: protein motif:HMM:NF012705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phytoene/squalene synthase family protein"
                     /protein_id="HDF2769619.1"
                     /translation="MYAICRIIDDSIDKYKDLEQLNGIARDLDVIYSDCDYIQAYQSD
                     AAIMNALSNTLNTYSIPKKPFESLIQYVKEDLVLKEMKTDSDLYEYCYGVADTVGELL
                     IPILTSSNENNFEQAEETAIALGKAMQITNILRDVGKDFQNGRIYLSVEKLAQYRVNL
                     HSIYYEGVTPNYIELWESYATEAVRLYDIALNGINYFDEEVRYIIELAAIAYHEILVE
                     VRKANYSLHKKVYVSKLKK"
     gene            26769..28274
                     /gene="crtI"
                     /locus_tag="PC466_002241"
     CDS             26769..28274
                     /gene="crtI"
                     /locus_tag="PC466_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002467554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phytoene desaturase"
                     /protein_id="HDF2769620.1"
                     /translation="MKIAVIGGGVSGLAAASRLAANGHQVDLYEKNQQIGGRMNQIKQ
                     DGFTFDMGPTIVMMPEIYRDVFNYAQKNMNDYLEIKQLSHIYDVYFSETDQIRVPTDL
                     AQLRDMLESIEPNSTHGFMSFLTDIYERYEIARKYFLERTFRKPTNFYNPFTIYQGMK
                     LKTFDKADNLIEKYVDNEKIQKILAFQTLYIGIDPKRSPSLYSIIPMIELMFGVHFIK
                     GGMYSFVRALQTLNEELGIQIYTNTNVEEIIIDGRYKCAEGIKVNGHIEKYDKIICTA
                     DFPYATSSLIKNEHHPKKYTTQKIDNMDYSCSAFLMYIGVDKDLSEDILLHNVIFSKD
                     FDNNINEIFSGEISQDPSIYVYAPSVEDQSLAPEGQTGIYVLMPVSELKTGDTDWSDE
                     STITQVKDIIYNKLSTIKALEDLKKQVVTEIIYTPKDFEGDYNAKFGAAFGLMPTLAQ
                     SNYYRPPNVSRDYKNLYFAGASVHPGAGVPIVLTSAKITVDAMLEDINNGI"
BASE COUNT         9856 a         4262 c         4912 g         9314 t
ORIGIN      
        1 ataaggattt attaaaatta ctaaagttaa aaggaattca tttcgaaaat tctttaagaa
       61 atgatcctct ttatagcgaa caatacgaag tatttagaaa tttactttag tatgcttagt
      121 ctgaatacat ggttttgcat ttctctacta accagtgtta taatttagtt aacaaggaaa
      181 ctagcataga tgtaccaatc ccctcactac ggcaatagtg aggggatttt taggtgtggc
      241 tatagtcgcc tatttattat tgcgattacg tagctaatgc gtaaataacg caataataca
      301 accactgatg actgtggtcg tgatgtgaac aaggatttct agcatagatt agcacctcct
      361 ctctgcgtct gaattgacgc ctgagagata ggcgaccttt atattatatc atctgtaatg
      421 ggtgagttac agatgacttc cgataagtca tcttacgtag tgttttaaaa cagctagatt
      481 tcttatagta ctatacttac agaatcataa aactctatca atgaaaaaag agatctcata
      541 tatgagatct ctttttaata tcactaaaaa ttgaatttgg ctttataaaa ctaatatacg
      601 taataatttt tataaatatt atgaaataaa tattttgact ctaatattct atgtttggtg
      661 cttggtttac atgtttttgg taacgtttga gtgcacaaaa accaatagta ctaataattg
      721 ttactattaa taattttttc acgcttaaca ttccttcttt agcattgtat tgtagtctac
      781 ttattgcttt gatagtaatt taattctaaa tcttttgatg tctgttgacg gatttttttc
      841 attaacgcag tatcattaat gagtgattta ccataagatg gaatcatttt ttgtatttta
      901 ggcatccatt cagattcata ttcagggaag tttttctcaa gtacttctaa agctacagat
      961 actgaagttg atgctcctgg agactctcct aataaagcta ttaccgaatg atcttcagaa
     1021 ttaacaactt ctgtaccaaa ctgaataaat cctttaccat attcgggagt atctttaatc
     1081 acttgtacac gtttgcctgc agtgtataac tgccaatctt catcacgtgc ttctggataa
     1141 aatgtacgta aatgattcat acaaccttct ttagtcatta atatttgatc aaatgaatat
     1201 ttgattaaag gtaggttttt agcagcagca gataataatg ttgtaatatt atatggtttg
     1261 accgatttaa ataaatcaag attagaacca ttttttaaga acttaggacc cacactagcg
     1321 aatggaccga ataataatgt acgttcacca tcaatatatc gagtatccaa gtgaggtact
     1381 gtcataggcg gtgtgccagg tggttcttta ccgtaaactt tggcatcgtg ttgggctata
     1441 atgtctgggt tagtacaaat taaaaattgt cctgtaatag ggaatccacc caaatgttta
     1501 ctttctggaa ttccagtttt ttgtaatagt ggaatagcgc caccaccagc accaataaat
     1561 acataatcag caagttcagt ttgaacatca ccgctgttac gttgacgcac tttaatttcc
     1621 catttaccat cttttcgatg gttaaagtct attacttcat gattgtattg gacattggca
     1681 ttaggatgtt gttcaatgtt tttagccatt ttacgagtaa gctctccaaa gttaacgtct
     1741 gtaccttcgt taatcttact agcagccata atatcacttg agctatgacc ctccatcatt
     1801 aatggaaccc attttctcat ctcttcaata tcttctgtat attcaatatt gtcgaacatt
     1861 ggaaaatcct tcatagcatg ataacgatcc tttaagaatt gaacgttatt tttacctcta
     1921 acaaaactaa tgtgaggtaa tggttgaata aattctttag ggttagaaat actattattt
     1981 ttaactaaat gaccccaaaa ttgttttgaa atctcaaact gttcattaat ttcttttgct
     2041 ttttctatat caattgatcc atcaggttgt ttcactgtat agttcaattc acataaagca
     2101 gcatgaccag ttccagcatt atgacgctca tttgaacttt cgataccagg acgatctaaa
     2161 cgttcatata gttttatatt ccaacttggt tctaactctt taagcataga actaaaagtt
     2221 gtgcttaaaa caccagcgcc aataacaaca actgtttttg actcttttgt attcataatt
     2281 gactcccttc ttttaagtac aaatattagt gtaatacaaa acatacagaa attaaaatac
     2341 ttatttttaa taagaactat tcttttatgg aatagataca tattctgtaa tattattgtt
     2401 atttctactt agcttattaa taagctaagt agaaatgtcc agatgcatac aaatactaat
     2461 aatgctatac taaaacgcat tgtcattttc attaattgtg attcatttcc tacttcatta
     2521 actgcagcag tagctatagc tatagattga ggtgatacaa ttttagccgt aacaccacca
     2581 gcaacgttag ctgccacaag taaggaccct ttagcaccaa tttgtccagc aacagaggct
     2641 tgtattggag caaacaatgc attgttattt acaactgatc cagtcataaa tacacctatc
     2701 caacctaaaa ctggtgataa tagtggaaat atagatccag ctttagcaat accttggccc
     2761 atagcactac ttaatccgcc ataagtcgtt actttagata cagctaggat aaaacatatt
     2821 gttaatacag aaatccatag ttctttcact gttaatccta atagtttccc agcgatttta
     2881 aaattcatgt tatttgcaat aataatagtc aaaatggctg taattaatat agctgtacca
     2941 gtttgtgcaa taaaattaaa agtgagtaca tttggtgcgt gcgttacatc attcatcgta
     3001 ccaggtacat taaaattaat tacaagagag tgtaatagtc ctttcttttc aaataatcct
     3061 ttaaagaatg atgaactcca tataagtaca ataacagtta aaatgatgaa aggactccat
     3121 gcataaacaa tatttttgaa tgaatgttta gttacacgtt taggttcttc attttgttgt
     3181 aatctaaata tgtttttagg ttgaaactta ctagagaata atgctaatgc aaccatagct
     3241 gccaatccag gtataatatc tgcaagttca ggacctgcaa atgatgttat aatcacttgt
     3301 aaaaacgtat aagttacaga aacaactaaa atagatggta atatctcttt aatacctctg
     3361 aatccatcaa tcataaatat taataagaaa ggcacaaaaa agctaataaa ccctaaagtt
     3421 aaattaccaa ttagtgctac ctcggtagca gacacatcac ctgataaatt taacgtatca
     3481 ataatagcta ctggaattcc tactgcaccg taagccccag cagcagcatt gcctactaaa
     3541 caatacatag ctgcctctaa aggtttgaat cccagctgcg taagtaatac agcgcatata
     3601 gcaattggta caccaaatcc ggctgcgcct tctaaaaatg cattaaatac aaaaccaatt
     3661 agtaataatt gaatacgttg atcttgtgaa atactagcta tactgtcttt aacaatatca
     3721 aattgaccac ttttggtaga aattttatac aaccatacgg ccataataac tataaaacca
     3781 atgggaataa taccttgata aaaaccttca aatgtggctc ctccagcaat gttcaaaggt
     3841 aatttaaaaa ctaataatgc tactaatatt gttataatca aagttgttaa tgcagcataa
     3901 acacctttca ttttaaatac tgttaaacac agtaagaaaa gaatgattgg tatagcagca
     3961 acgattgaag ataacaacaa attatgaaat ggatcaaatg aatgcactaa cataacaatt
     4021 tatactcctc ttttaatttt taagatacta ttctgcttct ctaatttcct ctgaaatatc
     4081 tttataatca atatccgtct tattaaagat ttcatcattg attgggaaat gttgttcgaa
     4141 tgtttcgaag ttctgaattt caaccttagc atcttctatt tcaaagtcta gcacatggcc
     4201 gccgaagtta cgatcatcat tcgcaaagtg tatatgaaat cctgaagatc caataccatg
     4261 gaatagttcg ggcgtgaaga aaccaacaac agttccttca acatacgttt cagtttgttc
     4321 aggctgtctg cgtgccgaat caattaatcg tgtatatggc ggctcttgtc caggcatcat
     4381 gcgaacgtgc atttttttga atactccaga aattttaaca gctgaaaata aattttcact
     4441 aagcattttt tcttttattt catcaaaaac agcttcagaa gttttatcct tagtttgata
     4501 tgttgtatct gctgtgaatt ttgtcactgt tgcataaggt gttaactcat caccttttag
     4561 ttcaacaaat tctttatatt cattcgcatg ataggcttta ccatctacaa atatcacttc
     4621 tccattagaa ccagttaatg tcgcaatacc taggtcacca tgttctaata gttcattaat
     4681 tgaggcagta ccttttaata gtcctgccat caatgttcct aatgtaccgt gttgatataa
     4741 gatattagtc ataaaagctt cactcctcaa ttactatttg attattaatt aaatgcatca
     4801 ggcaacatat tggttgaaag tttcacatta tctttataat ttacaggtat atcaatgact
     4861 acaggtcctt gaatttcata acctttttta atcgcatgtt ctaattcttc ttgatttgtg
     4921 acacgcattc cttttgcacc aaaagcttct gcatatttca cataatcaac tgaaccaaaa
     4981 tctacacctg atgaacgttc gtatttcatt tcttcttgga acttaaccat attatactta
     5041 ccatcattcc aaattaattg tatgatattt aaattttttc gaacagctgt ttctaaatct
     5101 tgtgctgaaa atagaaatcc accatcacca gctactgaga caacttgtgt atttggacgt
     5161 actagtgctg ctgaaatcgc ccaaggtaat gcaacaccta acgtttgcat tccattacta
     5221 aataacaaat gtctcggatt ataacttctg aatttacgtg ccatccaaat ataatgactt
     5281 ccgacatcaa cggtcaccgt agtatcatcc gttaacattt tttgcataga ttcgataatt
     5341 tcgattggat gtaatacacc atctttatga gttgctttaa tacccgtttc ttcaacaata
     5401 tgtgctctta actgttctaa ttcatctaaa tgttgttggt taataaatgg ttcatctact
     5461 ttgtcagata tcatttctat agttcctgca atattaccaa ttaattcttt agtaggttgc
     5521 atataatttg taatttctgc tggaacttca tcaatattga taacttttgt gtctaattcc
     5581 ttattccaat tacttgcttc gtactcaatc ggatcataac caattgtgac aactaaatca
     5641 cttttacgaa gcaattcatc tcctacttgg ttacggaata atcctacacg accaaagaag
     5701 tgattttcta aatcgcgact aatgacacca gcaccttgga atgtttcaac tactggtaaa
     5761 tttgtctttt caactaattt atggatagca tttgtttcat tcgcacttga acttctcata
     5821 ccggcgagta aaacaggaaa tgctgcattt ttaattgcat caatcacgtc atttatatct
     5881 tgctcactag gaacacctaa attgggcttt tgacatagtg ctatagcttt tgattctact
     5941 ggtgctgaaa tcacatcttg tggaatacta ataaaactcg caccattttt acctgatgtt
     6001 gctgttctca tagcattagt catgacttct gataaagatt caggatcttg tacttcttca
     6061 ctatactttg ttgaatattt taataatgcc gcattatcta tactttgatg tgttaaacgt
     6121 aataaatcat tacgtttaac ttgtcctcct aaagctaata cgggatctcc ttcagatgtt
     6181 gctgttaata gtccggtcgt taagttactg acacctggac cactcgttac aagtgcgaca
     6241 cctggtttac cagttagtcg tcctatacct tgggccatca ttgctgcgtt ttgctcgtga
     6301 cgcgtaacaa taagttcagg tccatcgtct tcaagtgcgt taaataaata atcaattttt
     6361 gcacctggaa taccaaatat atattccaca ccattatttt ttagagtatc aataactatg
     6421 ttagctgcat tataattttt attagtcatt tacattcatt tcctttcaag ttttacatta
     6481 catgtctata tctactagtt ttatacatat tcaatgaaat acatgtaatt tgtttgtgtc
     6541 tacattataa ccccatttca aacatgaata aaaatactta ttgacgatac taaacattct
     6601 tttatttcat actttaatta ctattaataa attataaggg gatggaataa tagatataag
     6661 gttctgttgc aaagttagaa aaatatagct aatcaccatt ttattgtgtc agtcttcgtt
     6721 taactgacta acatgtaact aatttcgtga caaggagaaa atccgtagat ctgaagagac
     6781 ctacggttcc ttttatataa tccataaata cattcaatgc ctttgagcgt gttctttgcc
     6841 gtattaatac ttcgatagct tgtcttcttc accttaatat gacgatgatc ttgttcaatg
     6901 aggttattaa gatacttaga tgtacaatga caattagatt tgagtttaaa atctttcctc
     6961 aacttagaca tggccacctt cattgaaggt gcttgatctg taataattgt ttgaggttta
     7021 ccaaactgtt taataagtct tttaataaac gcatatgctg attgattatc tcgtttctta
     7081 cgtaaccaaa tatctaatgt atgaccatct gcatcaatgg cacgatacaa ataacaccat
     7141 tttcctttga ttttgatata tgtctcatca atacgccact tataatacgc tttgttattc
     7201 tttttcttcc aaatttgata caaaatagga gcatattctt gaacccatcg atagaccgtt
     7261 gagtgatgaa cattcacgcc acgctctctt aatatttcag atatatcacg ataacttaat
     7321 gcatatctta agtagtagcc aacggctaca gtaataacat ccttatcgaa ttgtttatat
     7381 ctgaaatagt tcatacaaaa gactcctttt tgttaaaatt atactataaa attaactatg
     7441 caacagaacc gcttcttctg agtctgtaaa ttgataaacg ccaaagccta gtacatacaa
     7501 acttaagcta tttttgaatt cttatattcc acaacattaa ctctttatac cttcataagt
     7561 tcatatttta gccttttaaa atgtaaaaca tgaatataaa tttgaaacac gtttcttttt
     7621 gtattgacat taaacaggat tgacgtaaat tgacttatcg gaagttgtct atcgtcgtat
     7681 attcggagat gatataatat ataggtcgcc tatctctcag gcgtcaattt agacgcagag
     7741 aggaggtgca tatcagatgg tcgaagctct tgttcacatc acgaccacag tcatcagtgg
     7801 ttgtattgtt gcgttattta cgcattggct acgtacatgt aacaataaga aaaaataggc
     7861 gatattagcc aacacctaaa aatcccctca ctattgcgag tagtgagggg attggtgcat
     7921 ataatgcacg aagctcttgt taactaaatt ataacattgg ttaatggaga aatgcaaagc
     7981 aaagtgatat gtacggtatt agttacaagg tatcgtttta atatttttga cgctaattgt
     8041 caataattta aagggtaaat tatgaatgtt atatattgag agtttatctt tttttaaata
     8101 gattgtcatt agaacatgca ttaaatttag aataaataat acaaagatca aaattcatga
     8161 aaccaaattt ttgataactt cattaagctt cgtatcaata tacttatctt tatgtatgac
     8221 taaatagaaa tagcgtgtga tgtctaagtt tgttacttct agcttttcta aatcataagg
     8281 tgttaatgtt gatttagaaa caatagaaaa gcctttatca gcatgaacca tatttttaat
     8341 tagatttgtg ttattaattt ctactaaata agaggatgaa gtcatttgtg ataacgcatt
     8401 ttcttgatag actcttgtac ctgatccacg ttctctgata aaacatattg atttatttga
     8461 agatgatgac tttttacgaa ttagtactat ttcatcttga gcaatacgtc tactgtgtat
     8521 aatattactt tgaacctctt tttcgattat acctaaatcg atagtgttat tcttaatatg
     8581 ttgtaatact gtatcagaat tatttaaata cacatgaatg tataattcag gatatttttt
     8641 ggctaaatca gtaagatgtt gtgacaatcg atattcgcca taagtgtaac tactccctac
     8701 cgttacatct cccgaaattg tatcaggttg cattttcaaa tcgtgtctta aggtttgttc
     8761 taaacgctca cgttgtaaag catattgaaa tagtttctcc ccatcacttg ttaaagacat
     8821 tttagaatgt ctaaattcga aaatttttac atcatattcc agttctaatc gtttaatatc
     8881 acgacttatt gatggctgtg aagtatataa attttcgcag ctttagtaaa actttgcgtt
     8941 ttaactactt catttagaac ttttaatgaa tccattaact aggtctccta acatttgaat
     9001 acctctatta taacaaaaat gttatgagta atatactcaa tatttatttt acgttataac
     9061 tatgcgatgc taagctttgg ataaaggagg agttaaaaag tgaagtcctt aaaaagcaaa
     9121 gcctttattt atggtttatt attcacattt atcatcgcag ttataagttt attaggatca
     9181 aagttaccat ttttagataa gataggtgct ttaacaattg ctatactgat tgcgatttta
     9241 tatagacatt ttaagggtta tcctgaagca tatcgttcag gaatcgcatt ttcgtctaaa
     9301 cggttactga aattagctat tatattatat ggattaaagt taaatattta tgatgtaatt
     9361 ggaaagggta gcgatttgtt attaatcgat attggagtca tcctttttag tatcggatta
     9421 atgttgttac taaataaata tattaaagga gataaaaacc tcatcctatt attaggtatt
     9481 ggcactgggg tgtgtggcgc ggcagctatt gcagcagtat ctccaatatt aaaatctaga
     9541 gaaaaagatt ctgcgattag tattggtatt gtcgcactta ttggtactat attttcgctt
     9601 gcatatactg taatatattc tgtttttaca atatctcctg aagtatttgg ggtctggtca
     9661 ggtacaagtt tacatgaaat tgcacatgta attcttgctt cgggcttctc aggccaagag
     9721 gctttgagta tgggactgtt aggaaaactg ggacgtgtgt ttttattaat acctctgagt
     9781 attattttaa ttttaattat gagaaaaaaa tcgcatagtg agaatgaaaa aaagcgtatt
     9841 gatgtacctt actttttact tggttttgtc atgatggcat tattccatac ttatgtatcc
     9901 ttgccacaca tggttatgca aattatagat aatatcacta ctatatgctt attgatggca
     9961 atggttgcat tagggttaaa tgtttcattt aaagacttaa aagatcgtgc tttcaaacca
    10021 ttaatagttg tcattattgt atctatttgt ttatcaactg tgacatttat tgttgctaag
    10081 tacttttata gttagactat aagtatatta aaaaattgat atagattctc acaaacaaac
    10141 acaacacatt gaaggcattc catattacta tggccaaaaa agatcagcct ttttcttact
    10201 aggcctattc ttctttatta ttactgacat atcaagcttt acaatgcata ttcctactta
    10261 ccttgacagt ttaattatag taaatttcaa tatttctatt aactatggaa caatataatt
    10321 tagggtacac cctaatcata cagacacagt tgttgaattt ataacaactg tcactgtact
    10381 tggtatatga gaataatttt acttaataaa tgagaaagcg cagtacactc actgctttaa
    10441 gattggctaa taagatatta ttactaatat aaaatttgat tcttgtttaa ttatgaatac
    10501 tagacttatg ggttgatttt tagtttagaa agagttatta tattttgtgt accgaccggt
    10561 aggtttaaaa ataaaaagta agtatcatac tttcttttag taataaggtg gtaagtagtt
    10621 atgtcaaaaa aacttgagat attaacaatt gcccgtgaag ttatacattc aaaaggttac
    10681 aaggcgactt ctattagtga catattaaat gctgctgata ttggaaaagg acaattttac
    10741 tattactttt cttctaagcg agatttaggt ttagcagtga tagatgattt agttgaagac
    10801 tggactgaac aattaataaa cagtaaactt cataatagtg aaaatcctaa agagaattta
    10861 aatgctatgc tagactggtc ctttaaatat catgatgata tgagctcaaa agctggatgt
    10921 cctgttggta atcttgcgat tgaaatgagt gagcatgatg atcttttcag agaaaagata
    10981 caagctttta tcgataagtg gatactttca atgaaagaaa atctcgatgg tttgaaagca
    11041 caagagttta taggaaattt agatacagaa aagcatgcgc aaactatttt ttcaactatc
    11101 gaaggtgcaa ttatgttgac taaagtgaaa caagatgttg aatatttaaa aaatgtgatt
    11161 gaaattataa gatggcaata taatttaacg tgatttataa atcacgttaa attcttataa
    11221 ttacaatacc aactggtagg tatatttaga ttcttagatt accaccaaat tgtgatgttt
    11281 ttatttatga ataggaggaa gtataaatgg ctgaacaagt ggattttgat gttgcaatta
    11341 ttggtgctgg accagcaggt atgacagctg ctgtttatgc atcacgtgca aacttaagta
    11401 ctgtaatgat tgaacgtggt atgccaggtg gtcaaatggc aaatacagaa gaagttgaaa
    11461 atttccctgg ttttgaaatg gttacaggac cagatttatc aacaaaaatg tttgaacatg
    11521 cgaaaaaatt tggtgctcaa taccaatatg gcgatattaa atcaattgaa gataaaggtg
    11581 gctacaaagt catcaatctt ggaaataaag aaataacagc acgcgcagtg attatttcaa
    11641 cgggtgctga atataaaaaa attggtgtac caggcgaaca agaccttggt ggccgtggtg
    11701 taagttattg tgctgtatgt gatggtgcat tctttaaagg gaagaaatta ttcgttatcg
    11761 gcggcggaga ttctgcagtt gaagaaggaa cattcttaac aaaatttgct gacagtgtaa
    11821 ctattgttca tcgtagagac gaattacgtg cacagaaaat cctacaagat cgtgcattta
    11881 aaaatgataa aatcgacttt atttggagcc acacattaaa aacaattaat gataaagatg
    11941 gcaaagtagg atctgtaacg ttagaatcaa caaaagatgg ttctgaacaa acattagatg
    12001 cagatggcgt gttcatctat atcggtatga aaccattaac aacaccattc ttagacttag
    12061 gtattacaaa cgacgtaggt tatatcgaaa caaatgaaga tatgagcaca aaagtacctg
    12121 gtatctatgc agctggtgat gtgcgtgata aaggtttacg tcaaatcgta acagctacgg
    12181 gtgatggtag tattgctgca caaagcgcta ttgcttatat tgagcactta aatgataaca
    12241 gtgagatact atctatttaa tccttatttt taaaataaaa gactaattta ttgcttttaa
    12301 atttagaata agttattgta ttttatgtac cgaccggtag gtattttata ttaggaacta
    12361 taataatcta ccgaggagaa gcacaacaat tgaaaataac ccataaaagg atttagcttt
    12421 aaaataattg taccaactag taggtacacg attaaaggag tttttgaaat gttacaaaat
    12481 gatagtttat acaagagatc cgatacaaag agattagttg aatttacaaa actttctcat
    12541 gattctttta aaagctttat ggaattttat catcaagttt tatcagaagg tcatttaagt
    12601 aaaaagttta aagaggttat ctcaatagca gtagcacata caactggatg tgcacattgt
    12661 attgatcacc atgttaagca gtttaaaaaa ttaggtggta caaaagaaga aatggctgaa
    12721 tcaattatgg tagcaactgc attaaaagct ggttctgcta tggcacatag tgttaatgcg
    12781 ctaaatgcat atgacgaaat tgaagatgac gaactatata aagcttctta ttttaacagg
    12841 ttgaaagaac ttggacaatt agatggagaa cgttttaaag catttataaa ctttgatcaa
    12901 caagcaatga aagcaggact attaactgtt aaagaaaaag aattaattgc gattgcagtg
    12961 gcacatacaa caggttgtcc atattgcatc gacattcata ctaaatctgc taaaaaagca
    13021 aaagttacaa aagaagaagt tgcggaagca atattagtag caacgttatt aaaagcaggt
    13081 tctgctatgt cccatggtgt taatgcctta aatgcatacg atgagtaaat aacttacgtg
    13141 acatatacca ttgattatag gagaaaatta tgaataacaa ataacagttc gaacctttat
    13201 tcgaaccatt taatctagga aatttgaact taaaaaaccg tattgtgatg gcacctatga
    13261 ctagaaatgc ctctccaaat ggtatccctg gtcaaaatgt aagagattat tatactagaa
    13321 gagctgaaaa taatgtgagt ttaattatta cagaaggtac atttattaat catcctgatg
    13381 tagcttcaga agtacccgca tggcaacacg atgtaccaca tatgtatggt gaattagcgt
    13441 tgaaaggatg ggcggatata gttaattctg tccataatgc aggtggtaag attttttctc
    13501 aactttggca tatgggtgga agaggcaatg tagacgatta tactattcaa gaaatcaatg
    13561 gattgattga tgcttatgtt gaaggtgctc taaatgcaca aaaagtagga tttgatgata
    13621 tagagctttt agctggtcat ggttttttaa tagatcaatt tttctgggag cgtacaaatc
    13681 atcgaactga taactatggt ggaagtcttg ctaaacgttc tacatttgct agcgaacttg
    13741 tcggttcgat tagaagagca gtaggaccca atttcccaat atcatttaga atatcccaat
    13801 ggaaatataa tttttaccaa gaaaaactgg ctaataaccc agaagaacta gaaacattca
    13861 ttaagccaat ttctgaagct ggtgtagata tatttcatgg tagcacaaga agattttggg
    13921 aagctgagtt taaaaactct gaattaaatc tgtcaggttg gataaaaaaa gtgacgggta
    13981 aaccaacaat tacaattggt tcgattagtt tggaaggttc tgatttcatt aactattttg
    14041 atgaaggacg agaagcagaa cataatacca ataaaatgac aggattagtt cgcaaattag
    14101 aaaatggtga gtttgattta gttgctgttg gtcgtgcgat tttagtagat ccagaatggg
    14161 ctatgaaaat taaaaaaggg aaagttaatg aactaaaatc atttactaaa gacgcacaag
    14221 aaaaattata ttaaatacaa aaaatagttg atatggaggt tatagtatga acggtataaa
    14281 catgaatata attgaagaat tagcaaagga atattcacaa gaaccacaaa aagggattca
    14341 accatataag gctaatatta attggaataa tggtttaagt gcagtagcta aagtaggaaa
    14401 tcatgatgaa ttacttatag atgaacctga atggttagct ggaacaaata aaggaccaaa
    14461 ccccgttgaa tatttactca gtgcacttgg aggttgctta tcattatcat ttatattatc
    14521 agctaataat aaaaatcatg aaataaaagg attagatgtt gaagtgacgg gagacgtaga
    14581 tttaaatatc cttttaggac taaaagaggg aaatcctggt gtttataatt tgaatgtgac
    14641 ttttaacgta gatactgaaa tagaagatgt aaaaatcgag gaattgatgc atgatgcttt
    14701 atcaatttct gtagtaggaa atactgtcca aagtaaagtt caaataaacc ctgagtataa
    14761 acgtaagtag agttagtaat tgaaattgag aactaactga aatcaattaa aaaggagatt
    14821 taaaagatat ggcaacaata acagtaactg aaaaaacatt taataaaaca attgaaaaag
    14881 gtgtaaccct tgtagacttt tgggcaactt ggtgtccacc ttgtcaaatg caatcacctg
    14941 tattagaaga actaagtgat gagttggaag gtaaagtaat aattggaaaa gtagatgtcg
    15001 atgaagaaaa agctttggct gctaaatacc aaattcagag tatcccaaca ctattaatct
    15061 ttaaagatgg tgaattagtt aatactttaa taggatttaa tcctaaacca aatttagaga
    15121 atgcattgac taagtatttg taattacctt taaattttgg aaagtgataa tataaaaatg
    15181 actttagaag gatctgtata ataatggaaa aagtgatgaa ttataatgat ttattgcata
    15241 aaatgaatac gcaagaaaaa ctgatgttat atgtaatggc tgaaaattgt aatgtttgtc
    15301 atgctgattt tcctaaagta gatgtattag ctaaaaaaca taatgtagac agtgtgaaca
    15361 ttatgattaa tgagatacca gaagcagctg gtcaattatc actatttaca gctccagttg
    15421 ttattttatt ttataaaaat aaagaaatgc atcgccaagc aagaattatt gattttgaag
    15481 aattagagta tcgtattaaa caattaaatg aaattgaaag ttagtacatg tcaaaatgct
    15541 ctcctaaatt ctttgggaga gcatttatta tttagaaact aaaaagcatt tatatcatcg
    15601 atgattaccg aaagatattg tcatgcacaa taatcaatat gaacctttca gtgttgaaga
    15661 tattgaggaa tatgatgaaa aaatgcaatc atattataaa aatagaccaa tcaaagcacc
    15721 attttcaaca cgaacagtca agggatagag tgagcatatc aatgagcact tagctagaag
    15781 ctatgatcct aatatgcttg attatttaaa tactcaagca tatatataaa aataattttt
    15841 ataaacgagt gtacagaaaa taactgtttt ctgtacactc tttcttcata atccaaaatc
    15901 tatgaatatc agtatataat atgttcaaaa actcaacata aaatcaatgt tcataaaatg
    15961 atttagatac acctataaga gccttaagta atatattttt tcatagagtt taatctttaa
    16021 gcatcctata tactgtagaa cgacttacac ctgtttgttt agcaatttct tctcctgtaa
    16081 gtttttgctc atcgtataga aacttaattt ctcttttctt atggtcaggt aatgaaggcc
    16141 tcccgccttt tcgccctctt gctcgtgctg cttctaatcc ttttttcgta cgttcactta
    16201 ataagttagc ttcaagttca gcgaatgcac tcatcatagt aaagaacatc ttgcccatcg
    16261 catctttcgt tgatacattc atatcaataa tatgtaaatc aatgctgttt tcatcgaacc
    16321 attgggataa ctcaattaat tgtttcgttg tacgtccaag acgatctagt ttatagataa
    16381 ctagaatatc tccttcccgt aaataatcca aacacttatc aagttccgtt cttttcgttt
    16441 tgcgaccact cgctttctcg ctaaagatac gttcacaacc atattcctca agtgtatcaa
    16501 tctgtccatc aagactttga tcttgtgttg atacacgtgc ataaccaatt ttagccattt
    16561 gaataccacc tcttttaatc gttttatgag tacttactaa tgaaatctag ttctcgatgc
    16621 aaataaacgc gtctctcatc gtctaaaaac tcatgatttt tgatatttat gatacattga
    16681 ttataacaca agtttataga cttaaatatc caagaaaaac ctcttaatat taagttaaga
    16741 ggttttgtgt caaaaacgaa ggtttaattg atattgtatt atatataaac atgaataagg
    16801 aggaaagaca atgaaaaaat ctttaattgt tgtcacaaac attgcgaaat acgataattt
    16861 agaaaggcct acaggtgcgt ggttctcaga ggttacgcac tttgcaaaag atttctatga
    16921 cgcaggttat gaggttgact tcgtaagtcc caatggtgga tatgtacctc ttgatccagt
    16981 cagtcttagt cctgaaatga tgagtactga ggactggaaa tactatacga atcatgagta
    17041 catgaataaa tttggacaaa cgctatctcc gaaagaggtt aatcctaatg actatcaagc
    17101 catttacttc gcaggtggac atggtgcgat ttgggattta agaaataaca aagaactcaa
    17161 tgacattgct ttaagtattt acaataatca aggcgttctt tcatctgtat gtcatggtgc
    17221 tgttggttta ctagacatta aagaaaatgg cgattacctc gttcatcata aagacgtgac
    17281 tggttttaca aatagtgaag aacaagcaaa tggtacaact gaatacatgc catatttatt
    17341 agaagacgaa tttattagta acggtgcaca ttttaaaaaa gaggatgact ggagtaattt
    17401 cgcagtcgta gatggtcgca ttgtcactgg tcaaaatcct caatcaggac atgcagttgc
    17461 tgaacacgct ttaaaaatct tagctaatca ataattttaa aaaggagcga tacacatgaa
    17521 atcattaatt attggcgcta atggtggcgt cggtcaacat ctcgtacgta aactaaatgc
    17581 acgagatgtt gattttacgg ccggtgttag aaaagaagaa caagttgaag ctttaaaagc
    17641 agatggtatc gatgcaactt acattgatgt tgcaaaacaa tctattgatg aattaataga
    17701 attatttaaa ccgtatgacc aaatcctttt ttctgtcggt tctggtggag cacaggtgac
    17761 gatcaaacaa tcatagtaga tttagacggt tcagtgaaag caattaaagc aagtgaacac
    17821 gtcggtcgtc aacactttgt tatggtatca acgtacgatt cacgtcgaga agcttttgat
    17881 gcgtcaggcg acttgaaacc atacaccatt gctaaacatt atgcggatga ctacttaaga
    17941 catgcaaatt taaaatatac catcgtgcat ccaggcgcat taactaacaa tcatgaaacg
    18001 caacaattca atatgagtgc tcaatttgaa aatgtacaaa atccgtctat cacgagagaa
    18061 gatgtagcag aagtgcttgt ttctgtgtta actgatgaaa cattacaagg tcacgaattc
    18121 caaatcatca atggtgattt gtcattatca gacgctacta ctaaatatct ggaggaataa
    18181 tcaatgaata atcaacaagt tgtacttgca aaacgaccac aaagtatccc tcaagatgat
    18241 gtatttagat ttgaaacaat agaaactcga gaaccacatg caggtgaggt tcaagtagaa
    18301 tccatttatg tatctgtaga tccttacatg agaggcagaa tgaatgatac aaaaagttat
    18361 gttcaacctt tccaagtgaa tgagccatta caaggtcata ttgttggaaa agtcacacaa
    18421 tcgaacgatg aacgtctatc tgttggcgat tatgtcacag gcatattacc atggaaaaag
    18481 ataaatacag tgaatggaga cgatgtgacc cctgtgccat caaaagatgt accattacat
    18541 ttatatttga gtgttttagg catgccggga atgacggcat atacaggatt gcttcaaatt
    18601 ggtcaaccac aatctggcga gacggttgtc gtgtcagctg catcaggtgc agtaggatct
    18661 gtcgtaggac aaattgctaa gattaaaggc gcaaaagttg tcggtattgc tggtggtaag
    18721 cagaaaacaa catatttaac agatgaatta ggatttgatg cggccattga ctataaacaa
    18781 gatgatttcg cacagcaact cgaagcggct gtaccagatg gtattgatgt gtattttgaa
    18841 aatgtaggcg gcgtaatttc tgatgaagtg tttaaacact taaatcgatt tgcacgcgtt
    18901 ccggtatgtg gtgcaatttc agcatataat aatgaaaaag acgatattgg accacgtatc
    18961 caaggaacgt tgattaaaaa tcaagcattg atgcaaggtt ttgtagtagc acaattcgct
    19021 gatcatttta aagaagcaag cgaacaactc gcacaatggg tgtctgaagg taaaattaaa
    19081 tttgaagtga cgatagatga aggttttgac aatttacctt ctgcatttag aaagttattc
    19141 acaggagaga attttggtaa acaagttgtc aaagtcgctg aagaatagga gaagactatg
    19201 aaaaatatca tagtaagatt catatttagt ttaatgtttt ataaaagtgg tgttgcacac
    19261 tttaaaaata aagatatgtt tttaaaaatc gtgccgtcct atttaccttt caaacacgca
    19321 atagttaagt attcgggcat attagaattt ataattgctt tttatgtact cggtgctaaa
    19381 aatagatcac gcgtaagaaa agtagtacaa ggattccttt ggctcgtatt tcctgcaaat
    19441 atttacgctg cacgtaagaa catctcttac aaagatgaaa gagatgaaac agatagtgtt
    19501 aagcagcatg tcattcgttt accattacaa tttgtcatgc tcgcacttgc gaaactatta
    19561 taagacttat catagccacg cctggaacat tacttttgtt ccaggcgatt ttttaatatt
    19621 tacacttaaa attgacgtat atcaaatgat tctcttgaaa acgcttatgt gctctttgtt
    19681 taaataagtt catatcagac atttactttt caatttttct atagtgataa gcttctaaat
    19741 taagaaaagc ataagttaat ttgcttgtat gagtgtaaga agaaataaaa aatgtatttt
    19801 atcatgttat gctatcgcaa cattgtaaca ttaatgtaat aacgtgacct gtaagacaaa
    19861 tatgagggaa gggtttttat gaaaaaagtt tctaacttta ttttagcgag tagtttagtt
    19921 ttgggctttt tcgtaacgcc cgaattattt aatatcactc aagcacatgc gcaagaatct
    19981 gtgaaacctt attatattta cagtggttat acagcaaatc aaagtaattt tattctagat
    20041 aagaatttta aaacatctca aaaagctgat aacttcaaga ttaataatca caagattact
    20101 aaaaatgcat tagctaaaaa taataaagat ttacacgatc caacatatta cgaggtttct
    20161 aatcataaaa cgaatggtgt tttcttctta ttagacggta agtcagtgag caaaaaaatt
    20221 attgaatcgt tacggtgaac caaagtatac atctacatca gcctaagcca aagaatatat
    20281 gtataaaata gaaaatgatg acttttaaaa tataaagttg tagtagatac attgtaaaaa
    20341 taaacttaaa ttgctcaaat acttttcaat aatatcaaga tatatattaa atcgaaagtg
    20401 attatatagt accaaagcaa atattgtact aattccagat tatacaggaa aagataaaga
    20461 attttttata ctagtgacat cattaaagca agtaagatta ttcctttttt agtcaaattc
    20521 ttgtggtttg ataaatttat tgattaatta ttataaataa agattgaaaa gctttaagaa
    20581 aggtaaaatt ttaaataaga gacttggagc tcttgtcaat taagataatg agcaagtgag
    20641 ctcgttaagt taaagatgag ctgaggtaaa gtttacctgc tcatcttttt ctatttggag
    20701 tctaaatata tgaaaaaaat attattaaca ggcgcttcgg gatatatcgg tagtcattta
    20761 atgaataaat taaaagataa ctatgaaatt atagctattt ctagaaatat agaaaataaa
    20821 tcaaatgaac aaaatgttac ttggaaggca gctgacttgt ttgatttaaa tgaaatcact
    20881 gaggtaatgg aggatattga tatcgctata tatcttgtcc attctatgat gccttcagct
    20941 aagttgacgc aggcgagctt tgaagatatg gatgcattat tagctgataa ttttgctaaa
    21001 gccgcaagtt ataacaaagt tcagcatatt gtatttatga gtggtttgat acctaataca
    21061 aatgaattat caccacattt aagaagccgt ttagaatgcg aacagatttt aggatcatat
    21121 ggtgtaccag taagtacttt aagagctggt ttgattatag gttctaaagg aagttcttac
    21181 cctatattaa aaaaattagt agaaagatta cctggcctgt tactaccaaa atgggcttat
    21241 aatataacat tgccagttgc aatagacgac gtgattgacg gtttatataa aattgtagag
    21301 cgtaatccaa atgagaacga atcgatagat attggtggac ctagtcatat gacttataaa
    21361 gatctattca agcaaactgc agaggtacta gataaacgat tacctacgat agatttgcct
    21421 attattccca tttggctaag taaatattgg gtgaaactta tttcaggtgt tccaaaagaa
    21481 atggtctatc cgttaatgga tagcttaatt catgatatga ttagaaatga tgaaaatatt
    21541 gtgaaagaca tttctatagg caagattgat tataaggaaa gtgtgcgtaa tgccttggaa
    21601 gaagaaacta agacacaaaa gaaaggaaag tcatcacgta agggcgatat taaagatgtt
    21661 agagcaatat caagggtagt cttacctaaa gatgtaaata tgattcaatt ggcagaatca
    21721 tatgcaaatt ttttaaatag aattacatta aatgtcgtta atagtgattt taacgaagat
    21781 aactttacga ttagtgtgcc gtgtttaaat aaggacttac tattattaag gaaagatttt
    21841 aaagcttcta ataatgagag aattttatat cgaattgttg gtggagattt cgcttcagat
    21901 tcagatggtg gtaatgcgag attagagttt agaagattac ctaatagtga cgcatgtatc
    21961 atagcgttac aagaatatga accgacgtta ccttggtggg tatataagta tacccaagca
    22021 aaagtacata aaagtgtaat gaatcttttt aaattcaaga ttaatagcca aaaaactaat
    22081 aaaggagaat actttaatat gaagaagttt attttgccaa ttgttattac aggtgcaatt
    22141 gttttgaaag tatatggagt gaaaaagtat ttagctagaa aaaataacat gtccaatgcc
    22201 gaattgtaac ggctaaaata aaggctagtt ccttttacaa aaaaagaggg gatcaactat
    22261 gaaagcaaac gagataatta aaacaattat aaaagttata acaccaatta caggtggtaa
    22321 atttatagga aaatttgcag tgaaaaatgc gagaaaagat tataaaaata atgttaaacc
    22381 acttttttca ccacccggct atgtctttcc aattgtgtgg ccaatacttt atacaacgat
    22441 gggcgtatct tatgcattag tgactaataa atctactagt aaggctttga aaggtgctta
    22501 ttactcacaa ttaagcctga attatctatg gtcgatatta tacttcaaat ataaattacg
    22561 ctttagtgcg ttgatagaga gtgttgtatt actgggcgca gtagttacaa caactgtaaa
    22621 atttttcaat gtaaaaaaag ttgctggcat tttactagtt ccatatatgc tttggagcgc
    22681 ttttgctact tatttaacag ctggtaattg gtatttaaat aaagataacc caagctatac
    22741 agcgaaatct gagcattaaa ttgatgaaaa agattatata tattgcgcta tattggttta
    22801 tagttcaaat gattattgct caacttggta ctcgtattag ttataagttc ttagaaaaag
    22861 ataataagta ttttcgaagt tggaatattg aacaagaggg tcaattatgg caacaattag
    22921 ttaaagtgca atattggaaa gatcatttgc cagacggtca aaatcttaac cctaatatca
    22981 gtagtaaagc gactttcgat ctatctaaaa atatgaatga tatacagcga tttatattag
    23041 aaactagacg tgcagaggtg gttcatctgc tatccatatt tcctgttatt gcgtttttta
    23101 aagcgtcaaa aagtgttaaa ataattaatt ttatatatgt cattatagct aatgtgcctt
    23161 gtatgattgt tcagcgctat aatcgcccta agttaatacg tatgtataat aaattacaaa
    23221 taagaaaagg tgattaaatg ggaaataaga aagtggttgt cataggaggt ggcttgggag
    23281 ggattgctag cgcaatttgt atggctcaag caggctatca agtggattta tatgaacaaa
    23341 ataagcatat cggtggaaag gtaaataggt tagacataga tgactatgga tttgatctcg
    23401 gtccatcaat tttaaccatg cctaaagtat ttcaacgctt atttcaacga tgtgatgaaa
    23461 ggctagaaga ttatgttagc attcgtaagt taagtttaca gattagaaac gtttatccag
    23521 atggccaaat tttagattta tatgaatcca tggaagatat gttaacaaat aatgaatcgt
    23581 taacaaataa agatatagag caactttctt cgttttttag ttacgcacaa aagatacatc
    23641 aagttgctga aaaaagctac tttgataagg gattagatac gatgtttgca attattcgtt
    23701 atcatggtcc attttcagct ttaaagcaat tcgattattt tcatacaatg caacaagcca
    23761 ttaataaaag ggtagataac ccatatttaa gagaaatgct aggttatttc ataaaatatg
    23821 tcggctcctc atcttatgat gctccggctg tattgagttt attacctcaa atgcaacatg
    23881 aggaaggttt gtggtacgta gatggtggca ttcataagtt agcggaagcg atggaacaat
    23941 tagcgagaaa attaggtgtg ggcatacatt ttaacacccc tgtaaaacgt atcaattata
    24001 atagtcaaaa taaggtgaca gggataacaa tagaaagtaa taaggaaata tatgcagatt
    24061 acattatatc taatatggaa gtaatccctg tttataagta tttattgaat tttgatgcaa
    24121 accaaataaa caaattggaa cgtaaatttg agccagctag ttcaggttat gtcatgcatc
    24181 ttggtgtgga caaaagttat ccagagcttc aacatcataa ctttttcttt tcaagtaatt
    24241 ctaaagttaa ttatgatcaa gtttttcacc agtatgtttt gcctgaagat ccgactattt
    24301 atgtagtgaa tacaaataaa acagataaga cacaggcgcc agagggacac gagaatataa
    24361 aaatattgcc acacataccg tacattcaga gtaagtcatt tagtgaagca gaatatctgc
    24421 aattccaaga acgtatattg gataaattag agtccatggg cttgaaagat ttgagaaagc
    24481 acattgtata tgaagacgta tggacaccac atgatataga aaatacatac aattctaata
    24541 aaggagctat atatggcgta gtatccaata agaagaaaaa taaaggtttt aaatttccta
    24601 aaaaaagtca gtacttcaaa aatttgtact ttgtaggtgg ttctgtaaat cctggcgctg
    24661 gtatgcctat ggttactttg agtggtatgc aagtagcaga agctattatt aatggagaaa
    24721 gtagttgagg ctgaatgata ctttatataa tagcaatagt attgacgata ctatcactaa
    24781 taagtggaat gtgtatgtat gcgcgtcgag cgattataaa taactccgga aaaggaagag
    24841 gtcagacagc cctcagtatt attgtacctg ctagaaatga agcagagaac ttacctaaat
    24901 tacttaacag tataagtaaa aagcaagaaa tagaagtaat tgttatggat gatggttcaa
    24961 ctgatgagac acaagttgtc gctagatatt atggtgcgag cgtatatact gttgaaaatg
    25021 atactacatg gcaaggtaag tcacatgctt gttggcaagg tagcaaatat gcaacgcatg
    25081 atttattaat gtttgtggat gctgatgttc agtttgcttg tgatgatagt attcaaaata
    25141 tagccaatca atatgattta ctaggtggta aaggtttgtt gtcaatacaa ccttatcaca
    25201 agataaaaaa gctatatgaa aatatatcgg cgatttttaa tttaatgaca atcgtaggta
    25261 tgaatcaatt ttcaatcacg aaatcagcaa ataatgagca aggcgcgttt ggaccagtcc
    25321 ttgtgacaaa taagcaagat tataaattga cacaaggaca tttgaaagct aaaaatcaaa
    25381 tcattgaagg ctttgcaata agtaaagcat ataatcagca aggtttgcca gttagtttgc
    25441 atgaaggcca aggcgtagtg aattttagaa tgtattctca aggatataaa tcgctattag
    25501 agggttggag taaacatttt gcacttggct ctcaagtaac taaaaagtct acgcttacgt
    25561 ttgtattttt atggctattt ggttcactta caacagtttt agcgataatt ttttcaatta
    25621 atttaggctc gttatatata ttattagcta ttactctata ttttatatat gcgatacaat
    25681 ttcatatatt tattcgaaga acaggaaatt ttaatattgt tgcgagttta tgtcatccac
    25741 tgctcttcat atgctttgtc gtgatatttt ttaaatcatg gttagatatc aatgtattca
    25801 aacgtatata ttggaaaggc cgtagaatag atttgtagtt tattttttta tacaaatgtc
    25861 aagaagttct aggcttattg aggaggccaa taaatgaatc aattagagag attataacca
    25921 ttttcacaat ataatgaaag aacattcaaa aacgttctca tatgcctttg attttttgga
    25981 tttaaaaagg aaaaaagcaa tttgagctat ttatgcaatt tgcagaatta tagatgatag
    26041 tattgataaa tacaaagacc ttgagcaatt aaacggcata gctagagatt tagatgtgat
    26101 ttatagcgat tgtgattata ttcaagcgta tcaaagtgat gcagctatta tgaatgcttt
    26161 aagtaataca ttgaatacat attcaatacc taaaaaacct tttgaatctt taattcaata
    26221 tgtgaaggaa gatttagttt taaaagaaat gaaaactgat tcagatttat atgagtattg
    26281 ctatggtgtg gcagatactg tcggtgaatt gttaattcct atattaactt catcaaatga
    26341 aaataatttc gagcaagctg aagaaactgc gattgcttta ggcaaggcaa tgcaaataac
    26401 taatatttta agagatgtcg gcaaagattt tcaaaatgga agaatttatc taagtgtaga
    26461 aaaattagct caatatcgag ttaatctaca ttctatatat tatgaaggag ttacgccaaa
    26521 ttatatagaa ctgtgggaaa gttacgctac agaggcagtt aggttatatg atattgcatt
    26581 aaacggtatt aattattttg acgaagaggt acgttacatt atcgaattag ctgcgatagc
    26641 ttatcatgaa atacttgtgg aagtaaggaa ggcaaactat tcgttgcata agaaagtata
    26701 tgtaagcaaa ttgaaaaaat aaaaatttat cgtgaactta gtgcgaaata taataggagt
    26761 gaaacattat gaagattgcg gttataggcg gcggtgtttc aggtttagct gcagcttcaa
    26821 gattagcagc aaacggtcac caagtagatt tatatgaaaa gaaccaacaa ataggtggca
    26881 ggatgaatca gatcaagcaa gatggattta catttgatat gggaccaacc atcgtaatga
    26941 tgcctgagat ttatcgagac gtttttaatt acgctcaaaa aaatatgaat gattacttgg
    27001 aaattaaaca attatcacat atatatgatg tttattttag tgaaacagat caaattcgcg
    27061 ttcctacgga tcttgctcaa ttaagagata tgcttgaaag tattgaacct aactctacac
    27121 atggttttat gtccttttta acagatatat acgaaagata cgaaatagca cgaaaatatt
    27181 ttctagaacg tacgtttagg aaacctacaa atttttataa tccttttact atatatcaag
    27241 gtatgaaact caaaacattt gataaagcag ataatttaat tgaaaaatat gttgataatg
    27301 aaaaaatcca aaagatttta gcgtttcaaa cattatatat aggtatcgac cctaaacgaa
    27361 gcccgtcatt gtattcaatt atacccatga tagagttaat gtttggtgtt cactttataa
    27421 aaggtggtat gtatagcttt gtcagagcac ttcaaacgct aaatgaagaa ttaggtattc
    27481 aaatttatac caacacaaac gttgaagaaa ttatcattga tggtaggtat aagtgtgcgg
    27541 agggaataaa agtaaacgga catatagaaa agtatgacaa aataatttgt actgctgatt
    27601 tcccatatgc tacttcatct ttaattaaaa atgaacatca tcctaagaag tatacgacac
    27661 agaaaattga taatatggac tattcttgct cagccttttt aatgtacata ggggttgata
    27721 aagatttatc tgaagatatc ttgttacata atgttatatt ttcaaaagat tttgataata
    27781 atatcaatga aatattttcc ggagaaatat cccaagatcc atcaatatat gtatacgctc
    27841 ctagtgtgga agatcagtcg ttagcgccag aaggtcaaac aggtatttat gtgctgatgc
    27901 ccgtttcaga attgaaaaca ggtgatacgg attggtctga tgagtcaaca atcacacaag
    27961 tgaaagatat tatttacaat aagctttcta cgattaaagc gttagaagat ttgaaaaagc
    28021 aagttgtgac agaaattatt tatacaccta aggattttga aggagattat aatgctaaat
    28081 ttggagcagc ctttggttta atgcctactt tagcgcaaag taactattac agaccgccta
    28141 atgtgagcag agattacaaa aatttgtatt ttgctggagc tagtgttcat ccaggggcag
    28201 gagtgccaat tgtactgacg agtgctaaaa ttacagttga tgctatgtta gaagatatta
    28261 ataatggtat ataaaaaaat ggtaatataa gtttgtttga agttaacact tatccaggac
    28321 aacaattttt tatgccgaag atgc
//
LOCUS       DAMJYN010000047        28219 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.048, whole genome shotgun sequence.
ACCESSION   DAMJYN010000047 DAMJYN010000000
VERSION     DAMJYN010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 28219)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28219)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28219
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.048"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            166..543
                     /locus_tag="PC466_002242"
     CDS             166..543
                     /locus_tag="PC466_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF2769621.1"
                     /translation="MMIRKIPQAELKVMKFIWKVDVTVTSKDVIEAMEQKYGWKQTTT
                     LTLLSRLVKRGFLDAQKIDRYTHYTIRVKHKDYLSFETKDFLSNIHDDSLRSLISALH
                     DDENIGKDKLDFLESYFDNLKDE"
     gene            536..1570
                     /locus_tag="PC466_002243"
     CDS             536..1570
                     /locus_tag="PC466_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HDF2769622.1"
                     /translation="MNNYMLYVFENLIKTTIVCSLGICLLLFLKRYLFKKFSKRFNYY
                     IWLIIVFRMLLFLFNYTIVYEVKEPKENAVGNNITQIDISTDNNLMLYVAYLWLVVTI
                     VIAVYTFIKYTRFKNLVVDVSYDIEDNDVNCIYKNLLKELNIKKKIELRGSDELISPA
                     GMGLFKSYIFLPDYPYSKDELTWILKHELMHFKNKDILIKFLVLSVRIIYWFNPLVYV
                     MSNKVNLDCELCCDESVLTDCSLKDKKEYALALIKSIKLSKNYNSGILTTEFNKTSLE
                     KRLDSIVKKKGKNGILVLLILITLFSVTYFNFESISFDNSNSLRNMGILQKSGVDLKE
                     EDDISMRVIN"
     gene            1636..2223
                     /locus_tag="PC466_002244"
     CDS             1636..2223
                     /locus_tag="PC466_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan-binding protein"
                     /protein_id="HDF2769623.1"
                     /translation="MKNLKKILIITGCLTLISTSLVFANTTTDVDTSKDDDSIISSCT
                     ITGYEFTYENAPQSVKFDYEKKCEALNIKPSKNDIIFVNKDSIDANDVENYVEPKAYI
                     IRYKKGYVFEVTGPKSYTLNVSNTVVGYNRVESGNPVHLVQLLCRTLDGSSIDDDSEF
                     GPATYNAVKSLQGRLGLTRDGIVGRSTWDAAGRRL"
     gene            complement(2601..3362)
                     /locus_tag="PC466_002245"
                     /pseudo
     CDS             complement(2601..3362)
                     /locus_tag="PC466_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612258.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            3970..4347
                     /locus_tag="PC466_002246"
     CDS             3970..4347
                     /locus_tag="PC466_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF2769624.1"
                     /translation="MMIRKIPQAELKVMKFIWKVDATVTSKDVIEVMEQKYGWKQTTT
                     LTLLSRLVKRGFLNAQKIDRYTHYTVIVKHKDYLSFETKDFLSNIHDDSLKSLISALH
                     DDENIGKDTLDFLESYFDNLKNE"
     gene            4340..5374
                     /locus_tag="PC466_002247"
     CDS             4340..5374
                     /locus_tag="PC466_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease"
                     /protein_id="HDF2769625.1"
                     /translation="MNNYMLYVFDNLIKTTIVCSFGICLLLFLKRYFFKRFSKRFNYY
                     IWLVIVFRMLLFLFNYTVMYEVKEPKENTVGNNITQIDVSIDNDFMLYLVYLWLFVTI
                     AIAVYTFMEYTKFKNLVVDVSYDIEDHDVNCIYKNLLKELDIKKKIELRGSDELISPA
                     GMGLFKSYIFLPDYTYSKDELTWILKHELMHFKNKDILIKFLVLSVKIMYWFNPLVYI
                     MSNKVNLDCELCCDESVLTDCSLKDKKAYALALIKSIKLSKNYNSGILTTEFNKTNLE
                     KRLDSIIKKKGKSGILMLLILFTLFSVTYFNFESISFDNSNYLRNIGILEKTGADLKE
                     EDDISMRVVN"
     gene            5853..6026
                     /locus_tag="PC466_002248"
     CDS             5853..6026
                     /locus_tag="PC466_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan-binding protein"
                     /protein_id="HDF2769626.1"
                     /translation="MHLVQLLCQQINGSDIDPDSKFGPATYNQVKILQGRLGVTKDGV
                     VGKATWQAVGERY"
     gene            complement(6111..7133)
                     /locus_tag="PC466_002249"
     CDS             complement(6111..7133)
                     /locus_tag="PC466_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HDF2769627.1"
                     /translation="MNYNDLLKSARENFNGTCKVCKICNGLACAGDVPGMGGKGSGSS
                     FIENRKSLEKIKINMRVIHNVSKPDTSIELFGRKMSSPIFAAPVSGTLLNMGGKVSEK
                     EYIEPVVRGCSNSGIYAMVGDTNVDTFLLDNLDVLKDNSGNGIVFIKPWNNSKIIEKI
                     RLSEEAGAFAVGVDLDACGLINNQFQENPFSPKTIDEIRELVESTKLPFIIKGIMTVD
                     DALMAVESGASAIIVSNHGGRVLDYTPGTCEVLPDIAKSVKGKITILVDGGVRTGVDV
                     VKMLGLGADAVLMGRPFVTASFGGGLDGVEFFIEKVRNELCETMILTGCQNVKDIDGR
                     VIWNLL"
     gene            complement(7464..7646)
                     /locus_tag="PC466_002250"
     CDS             complement(7464..7646)
                     /locus_tag="PC466_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769628.1"
                     /translation="MYKDKSDECIHLMTAYIDSISGYYSFIDTQLEDFMVKYGENIVD
                     SNLHSIMMLLCKWGLS"
     gene            7959..8378
                     /locus_tag="PC466_002251"
     CDS             7959..8378
                     /locus_tag="PC466_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3785 domain-containing protein"
                     /protein_id="HDF2769629.1"
                     /translation="MSLYKFIYDDKEYLLKEENCSALINDEENPVQGVSISKIIDILN
                     EAEEVDFDVEYYQEACPLCLEGVKEKKKFFPFLEYHFYIFSKDGEYVISNISVDYKGL
                     SFNKLSRANKVDNSYIVSVIICENCQDYIVQIENCIV"
     gene            8509..10350
                     /locus_tag="PC466_002252"
     CDS             8509..10350
                     /locus_tag="PC466_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDF2769630.1"
                     /translation="MEEIDDTILDSMFKLTLNERLLTNNDFVENKIGVVKNLIDCYKT
                     EQNSLMLLKSNFLLALLYGIQGFSEKMKEYILISCKYIDKCLPKDYKFLARFYSQIAI
                     LSLKNEDVNKANLYMDKFNLICDENNFLIEEIIFKSQLIYIKASKCIESSVIIKEIET
                     LYIKIKEINDFNCKKIYFFIIGKIYFLFLDDALIAKVNFLKARKYADLLKDMQVSSLC
                     NIKIGECECSFENYECSIEYLNEVISNKKYRNVNIIQKYRASNNITKILIKTRNYPVA
                     INNLAKSEVYLEKIKNQSLKEVEKFDLFISLAMYYAKSNEKSFEQSICYLDRAKNILN
                     MIKNIEEYTIYDLEIIYHQAKIYYIFGYYDNALNTNKKLLEKSKNAKNYNYVKLAYKN
                     IYLCFEKIQNYEMSMKYFKMYYELKMMYIKARNRNYIDSLNYRHEYIETEINNMRKVK
                     LDLDKKKYVDHLTSAYNRTFLNDFLEKQEVSEYCTAFMIDVDYFKEYNDTYGHYNGDI
                     ALKNITIIIKKYLKKDMFMIRYGGEEFLILSVCKDYKKSKIFGRKLCRIVKKFLNNNL
                     TVSIGIDTCKNSSIDIREIIENADKALYKAKESGRNRCLHYHDFKNF"
     gene            10377..12263
                     /locus_tag="PC466_002253"
     CDS             10377..12263
                     /locus_tag="PC466_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDF2769631.1"
                     /translation="MKRSLIEDLKRNINKIEYDMLTKFYLNLTDLNYILDYHKDLLNT
                     KLEDNSRVYTLYLISLINYIKKDREASYNYLIESLKYIKKLSLKEDSDIISKIYIYLT
                     LSAISIRKYDKANNFYFSAKKVIRQNHLNELLVLLNMSLCVEISALYQTKTDVIALVE
                     EVSFFKTLKNKALVSRANYIFGRVYLYLFNNFIKSMEYLIECLKLAQENNLYSIEAFC
                     KCIISLCYLESGNNVEAIKYINNVLDVAHSKNSISVTERVSIKIDLIWAYLKEDMNKE
                     AEVILLKTIKLMKVVEGVYKDYLYSFIFLYSAEIELRKDNCSFEKVNTYLILSKNIYK
                     SFGDVFIYNSKLDYIYKLYGDLYIKFGNIDEGISCYIKGLNLVKKSSLNLRKISIFYG
                     LIANGYELKKDFKLAIEYYKSMDWYSDRWEKNNSYKTSQAIHKQYELRQKQESLRLLV
                     DDNKKLENDILKDGLTKLYNRRYLEQQLDLFNGTRDKNMVAILVDIDCFKSYNDNYGH
                     LAGDKVIVKVTDIIRSVFIDITEHIIRYGGEEILILVDSIESIGVEEIDNIELYIKRV
                     FKLLEFEGIEHIYSKIKNYITISAGVSIKRCRSRKDVEILIEDADKNLYKSKKAGRNQ
                     YIII"
     gene            12271..14271
                     /locus_tag="PC466_002254"
     CDS             12271..14271
                     /locus_tag="PC466_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2769632.1"
                     /translation="MILLRKKIGIIASDIELKERIEELYREDVENGTIIIDILNLDLM
                     ENQGRILVEKGAQAIIGRGGGYSLVIDTVNVPVIPMNMKSTDLLRAIEIAKKYSKKVV
                     LILGDNEVSFDYVGWRNVISTEITEEWFESKYEIRSKVVKYIDQKDEVVIVGGGLACS
                     FARQYGIDSVFATASDESIREAVEYCKKLLDTLGEEKFNNEVLRNILDGIKDGVIAID
                     SNGSIILYNESAKNMLKVERKCALNKYILDVFPKMEWMLDCLHEKEDVEDRKIRNINN
                     LIVNTRTTLIKVDNSTYGVLGIIQDITKLQNLERKIRFDLNQKGLYARYTFDDFLFKD
                     KLTREFIEEAKKIGKSDYTTLLYGESGSGKEIIAHSIHNISKRKDRPFVAINCATIAE
                     NLLESELFGYEEGAFTGARKGGKRGLFELAHGGTLFLDEINSLSFNIQTKLLRVIEER
                     QIMRIGSDYIIPLDIRIIAATNESLTEKIVMGTFRADLFYRLSSLEINIPPLRDRRED
                     IIPLFNNFVNEVLKDDGLNGINSIDENFVLTKDEMDKLYNYSWPGNVRELKTIAQKYV
                     VTGKIKLRQDRDFKTKKLLPNSEVDKFNSETTASVEVQDESINISKINDGKISIDIKE
                     VNKYVEEKIISMLFAQGLSKNEVAQVLGISRTSLWKKYNKNI"
     gene            14533..15792
                     /locus_tag="PC466_002255"
     CDS             14533..15792
                     /locus_tag="PC466_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HDF2769633.1"
                     /translation="MSQSMVGKHAMWPKENDVIFSISGRAQAAEKAFGMDNVINATIG
                     ALMDDSGKLITMKTVYEEYKALDNCEIGAYAALEGQPDYLEAVKKVFFRDYLPEGHIR
                     VLASPGGSGAIKLAVWNYTNEGDEVLTSDWFWSPYVSIAEEANRKVVNYQLFDENRRF
                     NFESFKEKFVNIAEKQGRVFTIINTPAHNPTGYSVADDEWDKILDLSKEVAKDKDKKI
                     IFFVDSAYIDFAGDDDVCRKFFKKFSNLPENVLVLVGFSMSKGFTAYGMRMGAIICIS
                     SSEDVAEEFHYSCVHSCRANWSNCNRSAMAVLSNIVNDPKKFKEYEDEKEIYKNMLTR
                     RADVFVEEAERVGLEILPYIAGFFVSIPCDNPKEVCEELTKHNLFAVPLKMGLRFAVC
                     AVSEDKCKKAPSIIKEALESLEVKINN"
     gene            15853..17640
                     /gene="iorA"
                     /locus_tag="PC466_002256"
     CDS             15853..17640
                     /gene="iorA"
                     /locus_tag="PC466_002256"
                     /EC_number="1.2.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indolepyruvate ferredoxin oxidoreductase subunit
                     alpha"
                     /protein_id="HDF2769634.1"
                     /translation="MKQLMTGNEAIARGAYEAGVKYASAYPGTPSTEILENIATYKDA
                     IVAEWAPNEKVALEAAIGGSIAGARTMASMKHVGLNVAADPIFTYAYTGVNGGMVLIT
                     ADEPGMHSSQNEQDNRMYAKFAKIPLFEPSTSQEAKDMIKEAFEVSEKYDTPVLYRVT
                     TRLCHSKGLVECYDREEVEIKEYVKNAKKMVTVPANAQIRRGVVEERMEILKKFSNET
                     DLNYYEMNDTKIGVIASGMCCNFAKEVFGKNASYMKLGFTNPLPYEKIKEFAEKVDKI
                     YVIEENDPFIEEQIKAYGIDCIGKDVIPPYGEMTPDVLRKAIFGKTNDTIEYKSELVT
                     PRPPSFCAGCPHRGFFYELGKRKNLIVGGDIGCYTLGFAPPYNGIDYVVCMGSAFGTA
                     HGAQKVLNMKDDNEKRLVGVLGDSTFFHTGINGLLDVVYNRGNSISVILDNRITGMTG
                     HQENPGSGYTLQGAKTKEVDIEGLVKACGIEHVRVINPNNLKEVNEALDWALAIEDEP
                     SVIITRWPCVLKKFSKEDIEEFNNPFKTKCKVDHDKCIGCKLCLKTGCPALSFDKENK
                     LSNIDRNQCVGCGVCAQVCPKQAIVKEEK"
     gene            17642..18217
                     /locus_tag="PC466_002257"
     CDS             17642..18217
                     /locus_tag="PC466_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indolepyruvate oxidoreductase subunit beta"
                     /protein_id="HDF2769635.1"
                     /translation="MTKSILLVGVGGQGTILASKLLTMGLMEAGYDVKMSEIHGMSQR
                     GGSVSSQVRYGDCVHSPVIEIGGADILVSFEKMEALRWFNYLKPEGKALVNNHRIDSM
                     TVLIGGAEYQESDIDAELSRLNAKVINAADKAEELGNSKIMNVILLGCLVKSMQLESI
                     DWEKIISENVKPKFVELNIKAFHEGMEMVSK"
     gene            18270..19340
                     /gene="buk"
                     /locus_tag="PC466_002258"
     CDS             18270..19340
                     /gene="buk"
                     /locus_tag="PC466_002258"
                     /EC_number="2.7.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="butyrate kinase"
                     /protein_id="HDF2769636.1"
                     /translation="MTYRILAINPGSTSTKIAVYDGEEQILVKTIDHPAEEIAKYNTI
                     QDQFEMRKEAVLNILKENSIDLKSLSAIVGRGGVLPPVKSGAYLVNEEMIDVLRHRPV
                     LEHASNLGAVVAHAISEPLGINSYIYDSVAVDELIDVARISGLCGMDRSSAGHALNTR
                     AMALKYAKDKGKDYKSLNLIVAHIGGGVSIYLHEKGRMVDMLSDDEGPFSPERSGRVP
                     ATKLVAACYSGQYSEREMTKKIRGKGGIVSYLNTVDAREVEKMIAEGNEEAKIIYEAM
                     AYQLAKGIGELATVVDGKVDAIIITGGIAYSEMFTSMVKKKVEFIAPVEIMAGENELE
                     SLAFGTLRVLNGEEEARIYSEN"
     gene            19558..20259
                     /locus_tag="PC466_002259"
     CDS             19558..20259
                     /locus_tag="PC466_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769637.1"
                     /translation="MGKISLKSMIRLFSGFFIFAISSVLMINAHVGLMPWDVLHQGLS
                     IKLGITIGQASIMVGVVIVILDAVFGENIGWGTLLNMTFIGIFIDLVIFSGVIPHASN
                     TYIGVFMVVIGIILAAIASFLYLGVCLGSGPRDGLMIALQKKTNKSVRLVRTILEILA
                     LVVGWLLGGSVGIGTLVSALGLGYVLQIVFRIFKFDTKLLKHRFIIDDIREWKEKRSN
                     EHKCKSSIVIKNEQN"
     gene            20318..20824
                     /locus_tag="PC466_002260"
     CDS             20318..20824
                     /locus_tag="PC466_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HDF2769638.1"
                     /translation="MELWDLYNADGIKTGNVIKRGNSIEEGYYHLAVEVWILNSNSQI
                     LIQKRSKSKKTLPNMWGMTTGCIVSGEDSLEGAIREAKEEIGIDITKDEMKVFRSMIH
                     EDTLWDVYLVKKEYDISKAILQEEEVSDIKWVSTDEIRQLLKEGLFFEYPEMYELLYE
                     IDNNKLNI"
     gene            20999..22021
                     /locus_tag="PC466_002261"
     CDS             20999..22021
                     /locus_tag="PC466_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HDF2769639.1"
                     /translation="MEDNKGLARDSSKYKIVSISVVVIILITFWYMLNMVLLTFIMTF
                     IFYNLLVATRKRIKKFSSLNIPDSLIIIVLYALFAILLVLISYAVVPIIIVQLTELSR
                     VFSDFDVNQFAQSLGPKLYPIVSKLDFNKYISQAGLLIASTATKVGSFGVNILLAFLL
                     SLLLLLEKNEIKNFGDKLSDSKISFIYNSLVFFGKSFVKNFGEVMKVQVMIAFINSVV
                     SMIFLGFMGFPQIWALGFMIFVLGLIPVAGVIVSLIPLTVIAFNTGGITKVFGVLLMI
                     CIVHAVETYILNPKLMSNRTKLPVCFVFIILLVGEHYLGVWGLLIGVPIFMFLMDILG
                     VKFTSR"
     gene            complement(22168..22476)
                     /locus_tag="PC466_002262"
     CDS             complement(22168..22476)
                     /locus_tag="PC466_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1540 domain-containing protein"
                     /protein_id="HDF2769640.1"
                     /translation="MKNNNLNCAATNCAYNTSGYCYAGSIKVDGMQATTTENTYCASF
                     EDKYTSGITSRSNETNQVDTDNIHCEAVKCKYNKNELCKAEKVHINERNASCETFEMK
                     "
     gene            complement(22536..22964)
                     /locus_tag="PC466_002263"
     CDS             complement(22536..22964)
                     /locus_tag="PC466_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769641.1"
                     /translation="MNNKLHELEKNLPETSCSFCTHLSFKGPSLDYRYDIRCVISDTK
                     PDFRGCCEYFEPEYTELNTGDLDNLYINFLETCLKVNYNDYINSMYWKLFKERTLLEN
                     NFKCSICGSTENVDVYHVNKNLGRETSKDVVVKCDKCNCK"
     gene            complement(23187..24644)
                     /locus_tag="PC466_002264"
     CDS             complement(23187..24644)
                     /locus_tag="PC466_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon starvation protein A"
                     /protein_id="HDF2769642.1"
                     /translation="MTTFLIGLAILLIGGALYGAYCEKVFGPDDRKTPALAQSDGVDY
                     VPMKKWKNSLIELLNIAGTGPILGPIQGILFGPIAFILIPIGCVFGGALHDYMSGMIS
                     IREKGAQMPSLISRFLGNKVFQVYNIFLCLLMLLVGAVFIYTPGDLVVTQILNMKSTI
                     NNPVVWIVYGLIFLYYLCATLFPIDKIIGKVYPIFGAILLLSAAGVGIGIFTQGYDLA
                     NLSLANWKGIHPDGIPLIPTFFVTVACGIVSGFHSTQATLIARSVSNEKEGKTTFYNM
                     MILEGLIAMIWAAAAMGIYNKGIPKELVGSPDVIGLVARDLLGSIGGIIAIIGVIVLP
                     ITSGDTALRSLRLMLADYFHYDQKEKKHRVILSICIFIPVIAILIFAKLSASGFNILW
                     RYFSWSNQTIAIFAFAMITVYLIIKEKNYIISLIPGMFYSFVIFSYIFNAQIGFNLNI
                     NISYVLAAIFTVLYAILTVRSGRKLKSKADTKLAD"
     gene            25062..25976
                     /gene="nadA"
                     /locus_tag="PC466_002265"
     CDS             25062..25976
                     /gene="nadA"
                     /locus_tag="PC466_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinolinate synthase NadA"
                     /protein_id="HDF2769643.1"
                     /translation="MDKDLTYQIKELKKEKNAIILAHFYQPPEIQELADAVGDSYYLS
                     EIARDCKEEVVVFCGVRFMGESAKLLSPEKTVLMPVSNAGCAMADMVDEEGVIKLKQQ
                     YPNALVVCYINSTAKVKAHCDVSVTSSSAIKILENIDNKEIIFLPDKNLGGYIAEQFP
                     DKNFIFWDGYCKYHNNIRAEEIIELKDKYKNAEVLVHPECKKEIRDLGDYVGSTSGII
                     KYATNSKNKDFIIATEEGILHELKKNNPNKNFYIPGGKILCTDMKKTTLENLYSTLKN
                     MENEVIVEDEIMEKALNSLLNMHKLAEG"
     gene            25989..27290
                     /locus_tag="PC466_002266"
     CDS             25989..27290
                     /locus_tag="PC466_002266"
                     /EC_number="1.4.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-aspartate oxidase"
                     /protein_id="HDF2769644.1"
                     /translation="MNLEQDVLIVGSGVSGLYCALNLDKSLNVLVVSKSTIENNNTYL
                     AQGGISTARNIDDIESFVEDTMKAGQYKNRVEAVQVLADESIENVGQIVEYGMPLDKE
                     NGEIDYTREGAHSVNRIVHSKDNTGEVVFKTLLKEAKTRENITLIEDAYLLDILKDGN
                     KCIGARIFKSKKEIHVFSKIVVLATGGIGGLFKNSTNQRHLTGDGIAIALRNNIKIEN
                     LEYIQIHPTAFYEENNEGRRMLISESLRGEGAKLLNKNKERFVDELLPRDVVSKAIFE
                     QMEKDKLPYVYLDATHLDSEYLINRFSFIYNECLARGTDITKECIKVSPAQHYFMGGI
                     HVDLDSKTSMENLYAVGEISCTGVHGANRLASNSLLEGLVFSKRAAKNINSVIDNVKV
                     KFIDVPDMDIDIEQVKKENKILVIKEIERTSEDFGDELFDY"
     gene            27271..28107
                     /gene="nadC"
                     /locus_tag="PC466_002267"
     CDS             27271..28107
                     /gene="nadC"
                     /locus_tag="PC466_002267"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HDF2769645.1"
                     /translation="MNYLIIDRMIQDALIEDVPSEDITTNSIVDENSKSTVDLICKQD
                     GIIAGLGVFKRVFEILGDVDVKLYKNDGDRVKNREKIAVLTGSTRNLLVGERVALNYL
                     QRMSGIATITSRYVEKLEGTNTKLLDSRKTIPNLRILDKYSVKVGGGCNHRFNLSDGI
                     LLKDNHIGAAGSVKKAVELARKNTSFVRKIEVEVETLDMVKEAIEANADIIMLDNMSL
                     EMAKQAVDIINGRAIVEFSGNVNLDTIEDIGKIGVDVVSVGALTHSVKALDISMKNLR
                     NI"
BASE COUNT        11057 a         2987 c         4700 g         9475 t
ORIGIN      
        1 gtaaaatatt taaatagata tattttaaaa tctaactttt aatattgtaa aaaaattaga
       61 aatttaacaa aaagtacaaa aattcacatt tttttcataa agtgtttgac taaaaaattc
      121 acatgttgta gaattaaggt agcaggagtt ttgagggagg tgtaaataat gataagaaaa
      181 ataccacaag cagaactaaa agtaatgaaa ttcatttgga aagtagatgt tacagtgaca
      241 tcaaaagatg ttattgaagc tatggaacaa aaatatggct ggaaacaaac tactacactg
      301 acacttttat ctaggctggt aaaaagagga ttcttagatg ctcaaaaaat agacagatat
      361 acacattaca caataagagt aaaacacaaa gattatttaa gttttgagac aaaggatttc
      421 ctaagtaata tacatgatga ctctttgaga agcttaattt cagcattaca tgatgatgaa
      481 aatataggta aagataagct agattttcta gaaagttatt ttgataactt aaaggatgaa
      541 taattatatg ctatatgttt ttgaaaatct tataaagaca actattgtat gtagtcttgg
      601 tatttgtcta ttattatttt tgaaaagata tttatttaag aagtttagta agagattcaa
      661 ttattatatt tggttgataa tagtctttag aatgttactt tttctattta attatacaat
      721 agtgtatgaa gtaaaagaac ccaaagaaaa tgcagtagga aataatatta cacaaattga
      781 tatttctaca gataataatc ttatgttgta tgtagcttat ttatggttag ttgtaactat
      841 agtcattgca gtttatacat ttataaagta tacaagattt aaaaatctag ttgttgatgt
      901 atcttatgat attgaagata atgatgtaaa ctgtatctac aaaaacttgt tgaaagaatt
      961 aaatataaaa aagaaaattg aattaagagg ttctgatgaa ttgataagcc cagcaggcat
     1021 gggattattt aaatcttaca tattcttacc agactatcct tatagtaaag atgaactaac
     1081 ttggattttg aaacatgaat taatgcattt taaaaataaa gatattttaa taaagttttt
     1141 agtgttatct gttagaataa tatattggtt taatccactt gtttatgtaa tgagcaataa
     1201 agtaaatcta gattgtgaat tatgttgtga tgaaagtgtt ttgactgatt gttctttaaa
     1261 ggataagaag gagtatgcat tagcacttat aaagtcaatt aaacttagta agaattataa
     1321 tagtggtatt ttaacaacag agtttaataa gacaagtctg gaaaagagac ttgacagtat
     1381 tgttaagaaa aaaggtaaaa atggaatatt ggtgttattg attttgatta cattattttc
     1441 agttacatat tttaattttg aaagtattag ttttgataat tcaaattctt taaggaatat
     1501 ggggatttta caaaaatcag gagtagatct taaggaagaa gatgatatta gcatgagagt
     1561 tataaattaa tagattaatg tatgtaatga aaaggtatat tgtcgtatta ttaataaatt
     1621 aggaggaatt atgaaatgaa aaatttaaaa aaaattttaa taattacagg ttgtctaact
     1681 ctaatatcta ctagtttggt atttgcaaat actactactg atgtagatac atcaaaggat
     1741 gatgattcaa taataagttc atgtactata actggttatg aatttacata tgaaaacgca
     1801 ccacaatctg taaaatttga ttatgaaaaa aaatgtgaag cgctaaatat aaaaccatct
     1861 aaaaatgata taatttttgt taacaaagat tctatagatg caaatgatgt agaaaactat
     1921 gttgagccaa aagcatatat tattagatat aaaaaaggtt atgtttttga agttactgga
     1981 cctaagagtt atacattaaa tgtaagtaat actgtagtcg gatataatcg tgttgaatca
     2041 ggtaatcctg tgcatttagt tcaactttta tgtagaacct tagatggttc aagtattgat
     2101 gatgatagtg aatttggacc tgctacatat aatgcagtta agtcacttca aggaagactt
     2161 ggattaacaa gagatggaat tgttggaaga agtacttggg atgcagctgg aagacgtctt
     2221 taaaaagaaa gctattgcac agataatttt aaattgctga atctgtaaac atttacatgt
     2281 attctttaaa taaaaattta ttttttaagt gataattaaa tttttactaa tagggctatg
     2341 gctttaaaaa tcatagcctt attttgatat cttttccatt tttgcaaaag ctattaaccc
     2401 tttaagaaaa tttcttgttt ttttgaaaaa tttctttctt caaaataaat acttaaatga
     2461 gctaaaattt gagcacaatt tctaattttc tgagtccatt tttaagaaat atatatggtt
     2521 gttaagtata gtgatttgtg caaataatta tccaaagtaa aaatagattt caatttagta
     2581 acttttctta ataatctatt ctaacttccc attgaatttg tagtatatat cgatgtattt
     2641 atttcttgag agtacttaaa atatgttact aattcattcc aattgtttca ccaacctctt
     2701 aatactattg tatattgatt gtactatttt ttctctagtg atagctcact taatgctacc
     2761 tcttctgtaa ttgtagcata tctttcttta aatcttttac agattctttt ctatttttat
     2821 atgatacata atttaaagta tttttaattt gatgcacaac atatctttgt acttaagtat
     2881 caggaaatat cgctttaatt gcattagaaa attcaactag tctatctata gaagctgcta
     2941 ttaatacatc tttaattccc atgtttctag catctataag cacttttagc caatactttg
     3001 aaatttcatt ttctccaatc catattctta aaacctcttt tatgctacat atagctatat
     3061 agactgtttt gtttattatt cgacctcact tctaacttta taatgtatag catctataaa
     3121 tacaattgaa taaattatat taagaggtct aagttaccat ttatgagtta aaggaataac
     3181 tttatcagta gttttagtta ttagtgaatg agataatatc aattccataa gtacttttaa
     3241 gatgacttaa tatattttga gtagacatgc cttttgagta tattccaatc acttgatttt
     3301 ttattcctaa tatatcattt tctatcataa cctaaaagtt cattaagctc cgcttctaac
     3361 atttaatgga ttgtactttc aaataaatct tttagtatat cttgaatatc tgtaattgtt
     3421 ttggcatcat attcttcaat aaattttttt aatattttag tttttgttaa acataaaaag
     3481 tgaacatctt cctttgtata gtagtgatat tttaattatc acaacttttt agaagaatac
     3541 aaactttatt ttaaagacac tgaaaatggt gtttttatac ctttatttgc tatgtataat
     3601 tttacttata acataaactt atataaaaca gatattttaa taacacaaag gtacaattag
     3661 gagattgtta aaatttatta gatattactc tagtttattt aaaaaaaagt attataatat
     3721 tccttgtgtg aaaatatagg aatttttatt aaataatttt aatgtggaaa taacattctg
     3781 cactattata attaaatatg taaaaagcaa aatacttgaa caactatatt ttaaaatcta
     3841 acttttagta ttttaaaaaa ttagaaaatt aataaaaagt acaaaaatcc acattttttc
     3901 ataaagcgtt tgactaaaaa attcacatat tgtagactta aagtagcaag agttttgagg
     3961 gaggtgtaaa tgatgataag aaaaatacca caagcagaac taaaagtaat gaaatttatt
     4021 tggaaagtag atgctacagt gacatcaaaa gatgttattg aagttatgga acaaaaatat
     4081 ggttggaaac aaaccactac actaacactt ttatcgaggt tagtaaaaag aggattctta
     4141 aatgctcaaa aaatagacag atatacacat tacacagtaa tagtaaaaca caaagattat
     4201 ttaagttttg agacaaagga tttcctaagt aatatacatg atgattcttt gaaaagctta
     4261 atttcagcat tacatgatga tgaaaatata ggtaaagaca cgctagattt tttagaaagt
     4321 tattttgata atttaaagaa tgaataatta tatgctatat gtttttgaca atcttataaa
     4381 gacaactatt gtatgtagtt ttggtatttg tctattatta tttttgaaaa gatatttttt
     4441 taagaggttt agtaagagat ttaattatta tatttggttg gtaatagtct ttagaatgtt
     4501 actttttcta tttaattata cagtaatgta tgaagtaaaa gagcccaagg aaaatacagt
     4561 aggaaataat attacacaaa ttgatgtttc tatagataat gattttatgc tgtatttagt
     4621 ttatttatgg ttatttgtaa ctatagccat tgcagtttat acatttatgg aatacacaaa
     4681 atttaaaaat ctcgttgttg atgtatctta tgatattgaa gatcatgatg taaattgtat
     4741 ctataaaaat ttgttaaaag aattagacat aaaaaagaaa attgagttaa gaggttctga
     4801 tgaattgata agtccagcag gtatgggatt atttaaatct tacatattct taccagacta
     4861 tacttatagt aaagatgagt taacttggat tttgaaacat gaattaatgc attttaaaaa
     4921 caaagatatt ttaataaagt ttttagtttt gtctgttaaa ataatgtatt ggtttaatcc
     4981 acttgtttat ataatgagca ataaagtaaa tctagattgt gaattatgtt gtgatgaaag
     5041 tgttttgact gattgctctt taaaagataa gaaagcatat gcgttagcac ttataaagtc
     5101 aattaaactt agtaagaatt ataatagtgg tattttaaca actgaattta ataagacaaa
     5161 tttggaaaag agacttgata gtattattaa gaaaaaaggg aaaagtggaa tattgatgtt
     5221 attgattttg tttacattat tttcagttac atattttaat tttgaaagta ttagttttga
     5281 taattcaaat tatttaagaa atatagggat tttagaaaaa acaggcgcag atcttaagga
     5341 agaagatgat attagcatga gagttgtaaa ttaatagatt tttatagtat tataatttat
     5401 taacaaatta ggagaagttt tgaaattaaa aatctaaaaa aaatcttagt agtcacaggg
     5461 agggtgactc taatatctat tagtttagta tttgcaaata ctaataatga tgtaaatgta
     5521 tgaaaaagta atgaagagca aacaacaaat tcatttacaa taactggtta cgaatttatt
     5581 tatgaaaatg taccacaacc tataaaatct gattatgaaa aaaatgtaaa gaattaaata
     5641 taaatccatc taaagatgat acaatcttta ttaatgaaaa atttatagat tcatataata
     5701 ttaatataga tgattataat attgaaccaa aagcatttat tattagatat aaaaaagatt
     5761 taaatcgttt tgatgctact ggtcctataa gttatagcgt aaatataaat accactgtag
     5821 taggatatgg acatgtagaa aaagggaatc ctgtgcattt agtacaactt ttatgtcaac
     5881 aaataaatgg ttctgatatt gatccagata gtaaatttgg acctgctaca tataatcaag
     5941 taaaaatact tcaaggaaga cttggtgtaa caaaagatgg tgttgttgga aaagccactt
     6001 ggcaagctgt cggagagcgt tattagaaaa gaggttgtcg cactaagaaa tagggcgaca
     6061 acttttttat atagaatata ttaatcagta tcttagagtc tagaaatatt ttacaataaa
     6121 ttccatataa ctctaccatc tatatcctta acattttgac aaccagtcaa aatcatagtc
     6181 tcacataact cattcctaac cttctctata aaaaactcca caccatcaag accaccgcca
     6241 aaagaagcag taacaaaagg tcttcccatc aaaacagcat cagcacccaa tccaagcatc
     6301 ttaactacat caacaccagt cctaactcca ccatcaacaa gtattgttat ctttcccttt
     6361 acagacttag ctatatctgg aagtacctca caagtaccag gagtataatc aagtactctt
     6421 ccaccatgat ttgaaacaat aatggcacta gcaccagact ctacagccat caaagcatca
     6481 tctacagtca taattccttt tataataaaa ggtaatttag tagattcaac caattctcta
     6541 atctcatcaa ttgtcttagg agaaaaagga ttttcttgaa attgattatt aataagtcca
     6601 caagcatcaa ggtctacacc aactgcaaaa gcacctgctt cttcagacaa tctaattttt
     6661 tctattatct ttgaattatt ccaaggcttt ataaatacaa ttccatttcc actattatct
     6721 ttcaacacat ctaaattatc cagtaaaaaa gtatctacat tagtatcgcc aaccatagca
     6781 taaattccag aattagaaca acctctaaca acaggctcta tgtattcttt ttcggaaact
     6841 ttaccaccca tgttcaatag agtacctgat acaggtgcag cgaatatagg agaactcatt
     6901 tttctaccaa ataattctat ggatgtatct ggctttgaaa cattatgtat aactctcata
     6961 tttatcttta ttttttctag actttttcta ttttcaatga aagacgaacc acttccttta
     7021 ccacccatac caggaacatc tccagcacaa gctaatccat tacaaatttt acatacttta
     7081 catgttccat taaagttctc tctagctgat tttagtaagt cattgtaatt catacaaaat
     7141 ctctcctttt tataatatta aaattgagta ttactatatt gaaaatatct taattgtaaa
     7201 tatagggatg ttattatgat gagctaaact agataataca tattagatat tttttattgt
     7261 tgtagatagt taaattatat catattagat agtcaaattt tgaaaaaaaa ctaacttatt
     7321 taagtataca ttttgaaaaa attaaaaaag ctatatatag atttttaaag aaatctatat
     7381 atagctttta agtttatgtc aatctttttt tattaatgaa taaataatat agaatacaat
     7441 atacaaaaaa gtttcttaaa atgctaagat aatccccatt tacaaagcaa catcattata
     7501 ctgtgtaaat ttgaatcaac aatgttttca ccatatttca ccataaaatc ttctaattgt
     7561 gtgtcaataa atgaataata tccacttata ctatcgatgt atgcagtcat taagtgtata
     7621 cattcatcac ttttatcttt atacatatat atctccccct atatacaata tataaattta
     7681 gatactaaat cgtatcatat taaatagtta agtgtgtaac atctatgcag ttatatattt
     7741 atatccttat attaataact aaagtgagtt ttgacaatag attttgggaa actggatgtt
     7801 caaagtgtaa acttggattt taaaatcatt aattaagata gtgtatagga atatatgtat
     7861 acataactta attataaaga ttataaacaa ttacttttat taactttatt taagtggtag
     7921 aataacttgg agattaataa ttataaggag gatataatat gagtttatac aagtttatat
     7981 atgatgataa ggaatattta ttaaaagagg agaactgtag tgctttaata aatgatgaag
     8041 aaaatccagt tcaaggagta agtatttcaa aaataattga tatacttaat gaagcagaag
     8101 aagttgattt tgatgtagaa tattatcaag aagcatgtcc attatgttta gaaggagtaa
     8161 aagaaaagaa aaaattcttt ccttttttag aatatcactt ttatattttc agtaaagatg
     8221 gagaatatgt aataagcaat atatctgttg attataaagg actatctttt aataaactat
     8281 caagggcaaa taaagttgat aatagttata ttgtaagtgt gataatttgt gaaaattgtc
     8341 aggattatat agttcagata gaaaattgta tagtttagtg taaagtatgt cttaatttaa
     8401 gagaaatttc taaattgaga catcaatttt tttcaaaaat agtatggaaa attactaaat
     8461 ttatgagata atgtaagtcg gaggtgagtt acaatatata gtaaatattt ggaagagata
     8521 gatgatacaa ttttagattc aatgtttaaa ctaaccttga atgaaagatt attgactaat
     8581 aacgattttg ttgaaaataa aattggtgta gtaaagaatt taattgattg ctataaaact
     8641 gaacaaaata gtttaatgtt attaaaatca aattttttgc tagctttatt atatggtatt
     8701 caagggttta gtgaaaaaat gaaagagtat attttgattt cctgtaaata tattgataaa
     8761 tgcttaccca aagattataa atttttagca cgattttatt cacaaatagc tattttaagt
     8821 ttaaaaaatg aagatgtaaa taaggcaaat ttatatatgg ataaatttaa tcttatttgt
     8881 gatgaaaata attttctaat tgaagaaatt atttttaaat cacaacttat ttacattaag
     8941 gcaagtaagt gtatagaatc ttctgtaata attaaagaaa tagaaacatt gtatataaag
     9001 ataaaagaaa ttaacgattt taactgtaaa aaaatatatt tttttattat tggtaaaata
     9061 tattttttgt ttttggatga tgctctaatt gctaaagtaa attttttaaa agcaagaaaa
     9121 tatgcagatt tactaaagga tatgcaagta tcttcactat gtaatataaa gataggtgag
     9181 tgtgaatgtt catttgaaaa ttatgaatgt tccatagaat atttaaatga agtaataagc
     9241 aataaaaagt atagaaatgt aaatataatt caaaaatata gagcatcaaa caacataact
     9301 aaaatattaa taaagactag aaattatcct gtagcaataa ataatttagc aaaatctgaa
     9361 gtatatctag aaaaaattaa aaatcagagc ttaaaagaag tagagaagtt tgatttattt
     9421 ataagtttag ctatgtatta tgcaaaaagt aatgaaaaat cttttgaaca atcaatatgc
     9481 tatttagata gagctaaaaa catcttaaat atgataaaaa atatagaaga atatacaata
     9541 tatgatttag aaataattta tcatcaggca aagatatatt atatctttgg atattatgac
     9601 aatgccttaa acacaaataa aaaactcctt gaaaaatcta aaaatgctaa aaattataat
     9661 tatgtgaagt tagcatacaa gaatatatat ttgtgttttg aaaagattca aaattatgaa
     9721 atgagtatga aatactttaa aatgtattat gagttaaaaa tgatgtatat aaaagctcga
     9781 aatagaaatt atatagattc cttaaattat agacatgagt atatagaaac agaaataaat
     9841 aacatgagaa aagtaaaact tgatttagat aaaaaaaaat atgttgacca tttgacaagt
     9901 gcatataata gaactttttt gaacgatttt ttagaaaaac aagaagttag tgaatattgc
     9961 acagcattta tgatagatgt agattacttt aaagaataca atgatactta tggacactat
    10021 aatggagata ttgctcttaa aaatataact ataataataa aaaaatatct aaaaaaagac
    10081 atgtttatga taaggtatgg tggagaagaa tttctgatat tatctgtatg taaagattat
    10141 aaaaaaagca aaatatttgg aagaaaatta tgtaggattg taaagaaatt tttaaacaat
    10201 aatttgacag ttagtattgg cattgataca tgtaaaaata gtagtataga tataagagaa
    10261 ataattgaaa atgctgataa agctttatat aaagcaaagg aaagtggtag aaatagatgt
    10321 ttgcattatc atgattttaa gaatttttaa ctgttgaaat aggattggtg atttacttga
    10381 aaaggagttt aatagaagat ttaaagagaa atataaacaa gatagaatac gatatgttga
    10441 ctaaattcta tctaaatttg acagatttaa actacatctt ggattatcac aaagaccttt
    10501 taaatacaaa actagaagat aatagtagag tctatacttt atatttaatt agccttataa
    10561 actatataaa aaaagataga gaagcatcat acaactattt gatagagtca ttaaagtata
    10621 ttaaaaaatt gtcattaaaa gaagattcag atataatatc taaaatttat atttatctta
    10681 ctttatcagc tatttctata agaaaatatg ataaggcaaa taatttttat ttctcagcaa
    10741 aaaaagttat aagacaaaat catttaaatg agttgctagt cttgttaaat atgagtttat
    10801 gtgtagaaat aagtgcttta tatcagacca aaacggatgt aatagcttta gtagaagaag
    10861 tgtctttttt taaaacttta aaaaataaag ctcttgtaag tagggcaaat tatatatttg
    10921 ggagagttta tctatattta tttaataact ttataaaaag tatggagtac ctaattgaat
    10981 gtctaaaact ggctcaagaa aataatttat attctataga ggctttttgt aaatgtataa
    11041 taagtttgtg ttatttagag agtggaaata atgtagaagc tataaaatac ataaataatg
    11101 tattagatgt tgcgcacagt aagaactcaa tatcagtaac tgaaagagtg tctataaaga
    11161 tagaccttat atgggcatat ttaaaagaag atatgaataa agaagcagaa gttattttat
    11221 taaagactat aaaattaatg aaagttgttg aaggtgtata taaggattat ttatattcat
    11281 ttatattttt atattcagct gaaattgagt taaggaaaga taattgtagt tttgaaaagg
    11341 taaataccta tttaatttta tcaaaaaata tatataaaag ttttggcgat gtttttatat
    11401 ataattctaa actagattac atatataagt tgtatggaga tttatatata aaatttggta
    11461 atatagatga aggtataagt tgttatataa aaggtttaaa tttagttaaa aagagttcat
    11521 tgaatcttag aaaaatatct atattttatg ggctaatagc aaatggatat gagctaaaaa
    11581 aagattttaa actggcaata gaatattata aaagtatgga ttggtattct gataggtggg
    11641 aaaaaaataa ttcctataaa acatctcaag caattcacaa acaatatgaa ctcagacaaa
    11701 aacaagagag tttaagatta ctagtggatg ataataagaa attagaaaat gatattttaa
    11761 aagatggact tactaaacta tataatagaa gatatttgga acagcagttg gatttattta
    11821 atggaaccag agacaaaaat atggttgcaa tactagtcga tatagattgt tttaaaagtt
    11881 ataatgataa ttatggtcat ctagcaggag ataaagttat agttaaggta actgatatta
    11941 taagaagtgt atttatagat attaccgaac atataatcag atatggggga gaagaaattt
    12001 taatactagt agattctata gaatcaatcg gtgttgaaga gattgataat atagaattat
    12061 atattaaaag agttttcaaa cttcttgaat ttgagggtat tgaacatata tattctaaaa
    12121 taaaaaacta tataactata agtgctggag taagtataaa aagatgtcgt agtagaaaag
    12181 atgttgaaat attaattgaa gatgcagata agaacctata taaatcaaaa aaagcaggta
    12241 gaaatcaata cattataatt taaaattgag gtgattttgt tgcgaaaaaa aataggaatt
    12301 atagcctctg atattgaatt aaaagaaaga atagaagaat tatatagaga agatgtagaa
    12361 aatggaacta taataatcga catacttaac ctagacttaa tggaaaatca aggtcgtata
    12421 cttgttgaaa aaggtgccca agctataatt ggtagaggtg gaggttatag tttagtaata
    12481 gatacagtaa atgtacctgt tataccaatg aatatgaagt caactgacct tttaagagca
    12541 atagaaatag caaagaaata ttctaaaaaa gtagtattga ttcttggaga caatgaagtt
    12601 tcttttgact atgttggctg gagaaatgtc ataagtactg aaataactga agaatggttt
    12661 gaatctaagt atgagataag aagtaaagtt gtaaaatata tagaccaaaa agatgaagtt
    12721 gtaatcgtag gaggaggttt ggcatgttct tttgcaaggc aatatggaat tgatagtgta
    12781 tttgcaactg ctagtgatga atctataaga gaagctgtag aatattgtaa aaaattattg
    12841 gatacattag gtgaagaaaa gtttaataat gaagtgttac gaaatatact tgatggtata
    12901 aaagatggag taattgctat agatagtaat ggtagtataa ttttgtacaa tgaaagtgca
    12961 aaaaacatgc ttaaagtaga gagaaaatgt gcacttaata aatacatctt agatgtattt
    13021 cctaaaatgg agtggatgtt agattgttta catgaaaaag aggatgtaga agatagaaag
    13081 ataagaaata taaataatct aattgttaat actaggacaa cattaataaa agttgataat
    13141 agtacttatg gagttttagg aataatacaa gatataacca agctacaaaa cttagaaaga
    13201 aaaataagat ttgacttgaa tcaaaaaggt ctctatgcta gatatacttt tgatgatttt
    13261 ttatttaaag ataaattaac tagagaattt attgaagaag ctaaaaaaat tggaaaaagt
    13321 gattatacaa ctttacttta tggagaaagt gggtctggta aagaaattat agctcatagt
    13381 atacacaata taagtaaaag aaaagatagg ccttttgttg ctataaattg tgctactata
    13441 gcagaaaatt tacttgaaag tgaacttttt ggctatgaag aaggtgcatt tactggtgct
    13501 agaaagggtg gaaaaagagg actatttgaa cttgctcatg gagggactct ttttttagat
    13561 gaaataaata gtctatcctt taatattcag acaaaactat taagagtaat agaggaacgt
    13621 caaataatga gaattggttc tgattatata atacctctgg atataaggat tatagcagca
    13681 acgaacgaat ctttaaccga aaaaatagtt atgggtacat ttagagcaga cttattttat
    13741 agattgagta gtttagagat aaatatacct cctttaagag acagaagaga agatataata
    13801 cctttgttta acaattttgt aaatgaagta ttaaaggatg atggtctcaa tggaataaac
    13861 agtatagatg aaaattttgt tttgactaaa gatgaaatgg ataagctata taattatagc
    13921 tggcctggaa atgtaagaga gttaaagaca atagctcaaa aatatgttgt gacaggtaaa
    13981 attaaattga gacaagatag agattttaaa actaaaaaat tacttcctaa ctctgaagta
    14041 gacaaattta attctgaaac gacagcaagt gtagaagtcc aagatgaatc tataaatata
    14101 agtaagataa atgatggtaa gataagtata gatataaaag aagtaaataa gtatgttgaa
    14161 gaaaaaataa taagtatgct ttttgctcag ggactttcta aaaatgaagt tgcacaagtt
    14221 cttggaataa gcaggacatc tttatggaag aaatacaata aaaatattta aatataatta
    14281 catataaatt attttgaagt aatgttaatt ttttaaaaca agtgttaaga aaaattaaca
    14341 ttactttttt gtaaattttt atttttttag acaggcatat atatttataa gaaaaatagt
    14401 taaaacactt aatttaataa tgaaaaaaat aataattcta aacaaaatca attttacata
    14461 aagtgggatt tattggcata gtaattgctt aatatataat gtaagagtaa atacaatttt
    14521 aggggtgatg gtatgagtca aagtatggtt ggtaagcatg caatgtggcc aaaagaaaat
    14581 gatgttatat ttagcatatc tggtagagct caagcagcag agaaggcttt tggtatggat
    14641 aatgtaataa atgcaacaat aggcgctcta atggatgatt caggaaaatt aataacaatg
    14701 aaaactgtat atgaagaata taaagcatta gataactgtg agataggtgc atatgcagct
    14761 cttgaaggtc aaccagacta cttagaagca gttaaaaaag tatttttcag agattactta
    14821 ccagaaggac atataagagt attagcttca ccaggaggaa gtggtgcaat aaaattagct
    14881 gtatggaact atactaatga aggagatgag gtattaacat ctgattggtt ttggagtcca
    14941 tatgtaagta tagctgaaga ggctaataga aaagtagtta attaccaact ttttgatgaa
    15001 aatagaaggt ttaattttga gtcgttcaaa gaaaaatttg taaatatagc agaaaaacaa
    15061 ggtagagtct ttacaattat aaacacacca gcgcataatc caactggata tagtgttgca
    15121 gatgatgagt gggataaaat attagactta tcaaaagaag tcgcaaaaga taaagacaaa
    15181 aagataatat ttttcgtaga ttcagcatat attgactttg caggtgatga tgatgtatgt
    15241 agaaagtttt ttaagaaatt ttctaatttg cctgaaaacg ttctcgtatt ggttggattc
    15301 agtatgtcaa aaggatttac agcttatggt atgagaatgg gggctataat ttgtatatct
    15361 tcaagtgaag atgtagctga agagttccat tactcatgtg ttcattcatg tagagcaaat
    15421 tggtcaaatt gtaatagaag tgccatggca gtattatcta acattgtaaa tgaccctaaa
    15481 aaattcaaag aatatgagga tgaaaaagaa atatacaaaa acatgcttac tagaagagca
    15541 gatgtatttg tagaagaagc tgaaagagta ggattagaaa ttcttccata tatagcaggt
    15601 ttctttgtaa gtataccatg tgataatcca aaagaagtat gtgaagaatt gactaaacat
    15661 aatttatttg cagttccatt aaaaatgggc ttaagatttg cagtttgtgc agtttctgaa
    15721 gataaatgta agaaagcacc aagtattata aaagaagcac ttgaaagttt agaagtaaaa
    15781 ataaataatt aatttcattg aacaaattgg gtggactatg aatttaataa ttgtagatgg
    15841 agggaatttt atatgaaaca attgatgaca ggtaatgaag caattgcacg tggagcctat
    15901 gaggctggtg ttaaatatgc atctgcatat ccagggactc caagtacaga aatattagaa
    15961 aatatagcaa catataaaga tgcaatagtt gcagagtggg ctccaaacga aaaggtagca
    16021 cttgaggctg ctataggggg ttcaattgca ggagcaagaa caatggcttc tatgaaacat
    16081 gttggtttga atgttgcagc tgatccaata tttacttatg catatacagg ggtaaatggt
    16141 ggtatggtac ttattacagc agatgagccg ggaatgcatt catctcaaaa tgagcaagat
    16201 aataggatgt atgcaaaatt tgcaaagata cctttatttg aaccatcaac tagtcaagaa
    16261 gctaaagata tgataaaaga agcttttgaa gttagtgaaa aatacgatac accagtttta
    16321 tatagagtta caacaagact ttgtcattca aaaggattag tggagtgcta tgatagagaa
    16381 gaagttgaaa ttaaagagta tgttaaaaat gctaagaaaa tggtaactgt tccagcaaat
    16441 gctcaaataa gaaggggcgt tgttgaagaa agaatggaaa tccttaaaaa attctcaaat
    16501 gaaactgatt taaactacta tgaaatgaat gatacaaaaa taggtgttat agcttctggt
    16561 atgtgttgta attttgccaa agaagttttt ggaaaaaatg catcatatat gaaactagga
    16621 tttacaaatc cattacctta tgaaaaaata aaagaatttg cagaaaaagt tgataaaata
    16681 tatgttatag aagaaaatga cccatttata gaagaacaaa taaaagcata tggaatagat
    16741 tgtattggaa aagatgtaat accaccatat ggagaaatga caccagatgt tttaagaaaa
    16801 gctatatttg gaaaaacaaa tgatactata gaatacaaat ctgaattagt aacaccaaga
    16861 ccaccaagtt tctgtgcagg atgtccacat agaggattct tctatgaact tggaaagaga
    16921 aaaaatttaa tagttggtgg agatataggt tgttatactc ttggatttgc tcctccatat
    16981 aatggaatag attatgttgt ttgtatgggt tctgcttttg gaactgcaca tggagctcaa
    17041 aaagttctta atatgaagga tgataatgaa aaaagattgg taggtgtact tggagactca
    17101 acattcttcc atacaggaat aaatggactt ttagatgttg tttacaatag aggtaattct
    17161 atttcggtta tattagataa tagaataact ggaatgacag gtcaccaaga aaacccaggt
    17221 tcagggtata ctttacaagg tgctaaaact aaagaagttg atatagaagg attagttaaa
    17281 gcttgtggaa tagaacatgt aagagttata aaccctaaca atttaaaaga agtaaatgaa
    17341 gcactagatt gggctttagc tatagaagat gaaccatcag taataataac aagatggcca
    17401 tgtgtactta aaaaattctc taaagaagat atagaagaat ttaataatcc atttaagact
    17461 aagtgtaaag ttgaccatga taaatgtata ggatgtaaat tatgtttgaa aactggatgt
    17521 ccagctctat catttgataa agagaataag ttatcaaata tagatagaaa tcagtgtgta
    17581 ggatgtggag tatgtgcaca agtttgtcca aaacaagcaa tagttaagga ggaaaaataa
    17641 tatgactaag agtatacttt tggtaggtgt aggaggtcaa ggaactatac ttgctagtaa
    17701 attattaact atgggattga tggaagctgg atatgatgta aagatgagtg aaatacatgg
    17761 aatgagtcaa agaggaggtt cagtttcctc acaagttaga tatggagatt gtgttcattc
    17821 tccagttata gaaattggtg gagcagatat attagtatct tttgaaaaaa tggaagcttt
    17881 aagatggttc aattatttaa aaccagaagg aaaagcttta gtaaataatc ataggataga
    17941 ttctatgact gttttaatcg gaggagctga atatcaagaa agtgatatag atgcagagtt
    18001 aagtagatta aatgcaaaag ttataaatgc agctgataaa gctgaagaac taggaaattc
    18061 aaaaataatg aatgttattt tattaggatg tctagttaaa tctatgcaat tagagtctat
    18121 tgattgggaa aaaattataa gtgaaaatgt taaaccaaaa tttgttgaat taaacataaa
    18181 agctttccat gaaggtatgg aaatggttag caaatagttt ataatagata taaatagact
    18241 atagaaatta aggtgaaagg aagaaaatta tgacttacag aatattagcc ataaatccag
    18301 gttctacttc tacaaaaata gcagtatatg atggagaaga acaaattctt gtgaagacga
    18361 tagaccatcc agctgaagag attgcaaaat ataatactat acaagaccag tttgaaatgc
    18421 gtaaggaagc agttttgaat attcttaaag aaaatagtat agacttaaaa tctcttagtg
    18481 caatagtagg aagaggtgga gttttaccac cagtaaaatc aggagcatat ctagtaaatg
    18541 aagaaatgat tgatgtacta agacatagac cagtacttga acacgcttcc aatttaggtg
    18601 ctgttgtggc acatgcaata tcagaacctc ttggaatcaa ctcatatatt tatgattctg
    18661 ttgcagtaga tgagcttata gatgtagcga gaatatctgg actttgtgga atggatagat
    18721 caagtgcagg gcatgcatta aatactagag caatggcttt aaaatatgct aaggataaag
    18781 gaaaagatta taagagctta aacttaatag tagctcacat tggtggagga gtaagtattt
    18841 atcttcatga aaaaggaaga atggttgata tgctatctga tgatgaagga ccattttctc
    18901 cagaaaggtc aggaagagta cctgctacaa aattagtggc tgcctgttat tcaggtcaat
    18961 attcagaaag agaaatgact aaaaagataa gaggtaaagg tggtatagtt tcatacctaa
    19021 atactgtaga tgctagagaa gttgaaaaaa tgatagcaga aggaaatgaa gaagcaaaaa
    19081 ttatttatga agcaatggct tatcagttag caaaaggtat tggagagtta gcaactgtag
    19141 tagatggaaa ggtagatgct ataattataa caggtggaat tgcatattct gaaatgttta
    19201 cttcaatggt taaaaagaaa gttgagttta tagcaccagt agaaattatg gcaggagaaa
    19261 atgagttgga atcacttgct tttggaactt taagagtact aaatggagaa gaagaagcta
    19321 gaatttatag tgaaaattaa taagaaaaat taaaaatgtt tatatactaa aaaagtggta
    19381 tatccgtttt ttatacacga aagcttagag tataggtgaa aatgtataaa atttggattg
    19441 ccacttttta taattaaaat tttatcttaa tctaataaat aattctgtaa aatttcgtat
    19501 ttatatatat attttattgg tatttattgt tattattatt atgaggagtg atttttgatg
    19561 ggaaaaataa gtttaaaaag tatgataaga ttattttcag gtttttttat atttgcaatt
    19621 tcttctgtgc ttatgattaa tgcacatgta ggtcttatgc cttgggatgt acttcaccaa
    19681 ggtttatcta taaagctagg cataactata ggtcaggctt ctataatggt aggagttgta
    19741 attgttatat tggatgcagt ttttggtgaa aatataggat ggggtacttt actcaacatg
    19801 acatttatag gaatttttat tgatttagta atattttctg gagtgatacc tcatgcaagc
    19861 aacacttata taggtgtgtt tatggttgtt ataggaatta ttttggcagc tatagcaagt
    19921 tttctatact taggtgtttg tttaggaagt ggaccgagag atgggcttat gattgctctt
    19981 cagaaaaaaa ctaataaatc tgtacgtctt gttagaacaa ttcttgaaat actagcatta
    20041 gttgttgggt ggttattagg aggttctgta ggtattggta cgcttgtaag tgctttaggt
    20101 ttaggatatg tattacaaat agtgtttaga atatttaaat ttgacacaaa gttgctgaaa
    20161 catagattta ttatagatga tataagagaa tggaaggaaa agagaagcaa tgaacataaa
    20221 tgtaaatcaa gtattgtaat aaaaaatgag cagaattaat tatgctaaaa tatatttgta
    20281 gtttatctaa tttatagtaa agtcaggaga ttttgaaatg gaattatggg atttatataa
    20341 tgctgatgga attaaaacag gaaatgttat aaaaagaggt aattctattg aagaaggtta
    20401 ttaccatttg gcagttgaag tgtggatttt aaatagtaac tctcaaattt taattcagaa
    20461 aaggtctaaa agtaaaaaga cattgccaaa tatgtgggga atgacaactg gatgtattgt
    20521 ttctggggaa gatagtttag aaggagcaat tcgcgaagca aaggaagaaa tagggataga
    20581 tataactaaa gatgagatga aagtttttag aagtatgatt catgaagata ctctttggga
    20641 tgtatactta gttaaaaaag aatatgatat atccaaagct attttacagg aggaagaagt
    20701 aagtgatata aagtgggtaa gcacagatga aataagacaa ttactaaaag agggtttgtt
    20761 ttttgaatat ccagagatgt acgaattgct atatgagata gataataata aattaaatat
    20821 atgatgtaga gcagatttca gtataagtaa gattatttaa aatgtatctt ctctaaattt
    20881 taatattgtt ttatgaaaat taataagtta tttttagtat ttttctactt gttttttgag
    20941 attaaaataa aaagggcagt cattataaag tcataaaaat ttggggagga tttaaactat
    21001 ggaagataac aaaggattgg cacgtgatag ttcaaaatat aaaattgttt ctatatctgt
    21061 cgtagtaatt attctaatta cattttggta tatgttaaat atggtgcttt taacatttat
    21121 tatgactttt attttctata acttgcttgt agccacaaga aaacgaatta agaagttttc
    21181 ttctttaaat attccagatt cattgataat tatagtgtta tatgcactat ttgctatatt
    21241 gttagtattg attagctatg cagttgtacc aataattata gttcaactta cagagctgag
    21301 tagggttttt agtgattttg atgtaaatca atttgctcaa tctttaggac caaaattgta
    21361 tcctattgtc tcaaagctgg attttaataa atatatttca caagcagggc tacttatagc
    21421 atcaacagca acaaaagttg gaagttttgg agtaaatata ttattggcat ttttactgag
    21481 tttactcctt ttacttgaaa aaaatgaaat taaaaatttt ggagataaac tttctgatag
    21541 taagatttct tttatttata attcgcttgt attttttgga aagagctttg ttaaaaattt
    21601 tggtgaagta atgaaagtac aagttatgat tgcctttata aattctgttg tttctatgat
    21661 tttcttaggt ttcatgggat tccctcaaat atgggcttta ggatttatga tttttgtgtt
    21721 gggtcttatt ccagtagcag gagttatagt gtctttgatt ccattaactg taatagcatt
    21781 taatacagga ggaataacaa aggtttttgg agttttactt atgatttgta tagtgcatgc
    21841 agtagaaaca tacatattaa accctaagtt gatgtcgaat agaactaaac ttccagtttg
    21901 ttttgttttt attattttac ttgtaggaga acattattta ggtgtatggg gattactaat
    21961 tggagttcca atatttatgt tccttatgga tattctgggt gttaaattta cttctaggta
    22021 atatattaaa ataataattt atttttatat ataaattatg aattgtttta aaaaagaacc
    22081 tataaataga catcattaat aaagacatct atttgatagg ttcaattttg ctttgtataa
    22141 atactataga attaaataaa aagaaattta tttcatttca aaagtttcac aacttgcatt
    22201 tctttcattt atatgaactt tttcagcttt gcaaagttca tttttattgt atttacattt
    22261 tacagcttca caatgaatgt tatctgtatc aacttggtta gtttcattag aacgactagt
    22321 tataccagat gtatatttgt cttcaaaaga agcacaataa gtattttctg tagtagttgc
    22381 ttgcattcca tctactttta tactaccagc ataacaatat ccactagtat tataagcaca
    22441 attagtagca gcacaattta aattattatt tttcataaat aacctcctaa gttttattta
    22501 aacttattat gtgaagttat ctaaatttta tacacttatt tacaattaca tttatcacat
    22561 ttaacaacta catctttgga agtttccctt cctaaatttt tattaacatg atacacatca
    22621 acattttcag ttgatccaca tatagaacat ttaaaattgt tttctagtag ggttctttct
    22681 ttaaataact tccaatacat agaattgatg taatcattat aatttacctt gaggcatgtc
    22741 tcaagaaagt ttatgtatag attgtctaaa tctcctgtat ttaattctgt atattctggt
    22801 tcaaaatatt cacaacatcc tctaaaatca ggctttgtat ctgaaataac acatctaata
    22861 tcatatctat agtctaggct aggcccctta aatgaaagat gtgtgcaaaa agaacaagat
    22921 gtttctggta gatttttttc aagttcatgt aatttattat tcataagtat tcctccaaaa
    22981 aatttatttt aagtatataa atgaatagat tattttaaaa cttttattta tttatattag
    23041 agatttagga taaatattcc aataaggagt aaatacttaa gtatttatta ctgtattaaa
    23101 taaaaaagag gcaaatctaa cttgagattg cctacttttt tatcattttt taataaaatt
    23161 tattctaagt attattttat ttagatttag tcagccaatt tagtatccgc tttgcttttt
    23221 aactttctac cagagcgtac agttaaaata gcatataata cagtaaatat ggcagctaaa
    23281 acatatgata tatttatgtt taagttaaat ccaatttgag cattaaatat ataactgaat
    23341 ataacaaaag aataaaacat accaggaatt aagcttataa tataattctt ttcttttatt
    23401 ataaggtaaa ctgtaatcat tgcaaatgca aatatggcaa tagtttgatt actccaagag
    23461 aagtatctcc acaatatatt aaatccagaa gcactaagct ttgcaaatat aagaatggct
    23521 atgacaggaa taaatataca gattgacaat ataacacgat gtttcttttc cttttggtca
    23581 taatgaaagt aatctgcaag cattaatctt aaagatctta aagctgtatc tccagaagtt
    23641 attggtaaaa caattacacc tattatagct atgataccac caatagaacc aagtaaatct
    23701 cttgcaacca aacctattac atcaggagaa cctactaatt ccttaggtat tcctttattg
    23761 taaataccca tagcagctgc agcccaaatc attgcaatta aaccttctaa aatcatcata
    23821 ttataaaaag tagtttttcc ttctttttca tttgaaactg atcttgctat aagagtagct
    23881 tgagttgagt ggaatccaga aacgatacca caagcaactg taacaaagaa tgtaggaata
    23941 agaggaatac catcaggatg aatacctttc caatttgcaa gacttaaatt agctaaatca
    24001 taaccttgtg taaagattcc aattccaaca ccagcagcag ataaaagtag aatagctcca
    24061 aatattggat atacctttcc tatgatttta tcaattggaa agagtgttgc acacaagtaa
    24121 tatagaaaga taagtccata aactatccag acaactggat tatttatagt cgatttcata
    24181 tttaaaattt gagtaacaac taaatcccca ggtgtataaa taaaaactgc accaactaaa
    24241 agcattaaaa gacaaaggaa tatattatag acttgaaata ctttattacc taaaaatcta
    24301 ctgataagag aaggcatttg tgctcctttt tctcttatac taatcattcc actcatatag
    24361 tcatgcaaag ctcctccaaa tacacagcca ataggtatta gtatgaatgc tattggacca
    24421 aacaatatac cttggatagg tcctagaatt ggtcctgtac cagctatatt aagcaactca
    24481 attagactat ttttccattt tttcattggg acatagtcta ctccatcact ttgagcaagt
    24541 gcaggtgttt ttctgtcatc tgggccaaat actttttcac aataagcacc gtataaagca
    24601 cctcctatta gtaatatagc caagccgatt aagaatgttg tcataatatc accccattta
    24661 taaaattttt tggtctttgt atacatatta tctaaatgtg tagatttata ttgaatttaa
    24721 ttctggacaa cctacaaatt ctataaagta ttacaactaa tataatttca gaaataaata
    24781 catatacata accatgtact tagtatacag gtatttggta atattttcaa tgttatagca
    24841 ataaagaata taaacaaaat tctgataata ttttacaaaa aaattaaaaa atataaaaat
    24901 tagtttaaat agatggagaa aaaaggaaaa tcaattgaga atataaatgt ctatatctta
    24961 acaatattaa gaggtttaaa attcttgaag aaagaatagt caagtgatat aatgggttta
    25021 caggtgtata tacactagta catatagaaa gcggtgcaat tatggataaa gatttaacat
    25081 atcaaatcaa agagctaaag aaagaaaaaa atgcaataat acttgcccat ttttatcaac
    25141 caccagaaat acaagaatta gcagatgcag ttggtgactc atattattta agtgagattg
    25201 ctagagattg taaagaagaa gtggttgtat tttgtggagt aaggtttatg ggagaaagtg
    25261 ctaagctatt atcacctgaa aaaactgtat tgatgccagt aagtaacgct gggtgtgcta
    25321 tggcagatat ggtagatgaa gaaggcgtga taaaattaaa acaacagtat ccaaatgctt
    25381 tggttgtatg ttatataaac tctacagcta aagttaaggc acattgtgat gtttctgtta
    25441 catcttctag tgcaattaaa atactagaaa acatagataa taaagaaatt atattccttc
    25501 cagataaaaa tttaggagga tatattgcag aacaatttcc agataaaaac tttatatttt
    25561 gggacggata ttgtaaatac cataacaata taagagctga agaaataatt gaattaaaag
    25621 ataagtataa aaatgcagaa gtattagtac atccagaatg taaaaaagaa ataagagatt
    25681 taggagatta tgtaggtagt acatccggaa taataaaata tgctactaat agtaaaaaca
    25741 aagactttat aatagcaact gaagaaggta tattacatga attaaagaaa aataatccta
    25801 ataaaaactt ttatattcct ggtggaaaaa tactatgtac agatatgaaa aagacaacat
    25861 tagaaaattt atatagtaca cttaaaaata tggaaaatga agttattgta gaagatgaaa
    25921 tcatggaaaa ggctttaaat tcactgctta acatgcacaa attagcagaa ggatagaggg
    25981 atagacttat gaatttagaa caagatgttt taatagttgg aagtggagtt tcaggattat
    26041 actgtgcatt aaatttagat aaaagtttaa atgtgctagt agtatcgaaa tcaacaattg
    26101 aaaacaacaa tacatatctt gcacaaggtg gaatttcaac tgctagaaat attgatgata
    26161 tagaatcctt tgtagaagat acaatgaagg ctgggcagta taaaaataga gttgaagcag
    26221 ttcaagtact tgcagatgaa tctatagaaa atgtagggca gatagtagaa tatggtatgc
    26281 ctttagacaa agaaaatgga gagatagatt acacaagaga aggagcacat agtgtaaatc
    26341 gaatagttca tagtaaggat aatactggag aagttgtttt taaaacttta ttaaaagaag
    26401 ctaaaactag agaaaatata actcttatag aagatgcata tcttttagat atattaaaag
    26461 atggcaataa atgtatagga gctagaattt ttaaatctaa aaaagagatt catgtttttt
    26521 caaaaatagt agttttagct acaggtggaa ttggtgggct ttttaaaaat tctactaatc
    26581 aaagacatct tacaggtgat ggaattgcaa tagctttaag aaataatata aaaatagaaa
    26641 atttagaata tattcaaata catcctacag ccttttatga agaaaataat gaaggtagga
    26701 gaatgcttat atctgaatca ttaagaggag agggagctaa acttttaaat aaaaataaag
    26761 aaagatttgt ggatgaactt cttcctagag atgtagtttc aaaagctatt tttgagcaaa
    26821 tggaaaaaga taaattacct tatgtgtatt tagatgcaac acatttagat agtgaatatt
    26881 taattaatag attttctttt atttataatg aatgtttagc tagaggaaca gatataacga
    26941 aagaatgtat aaaggtatct cctgcacaac attattttat gggcgggata catgtagatt
    27001 tggattcaaa aacatctatg gaaaatttat atgcagttgg tgaaattagt tgtacaggtg
    27061 ttcatggagc caatagattg gcaagtaatt cattacttga agggcttgta ttttcaaaaa
    27121 gagcagctaa aaatataaac tcagttatag ataatgtaaa agttaagttt atagatgtac
    27181 cagatatgga tatagatata gaacaggtaa aaaaagaaaa taaaatatta gtcataaaag
    27241 aaattgaaag aacaagtgag gattttggcg atgaattatt tgattattga tagaatgata
    27301 caggatgctt tgatagaaga tgttccaagt gaagatataa caactaattc tattgtggat
    27361 gaaaattcta aatctactgt agatttaatt tgcaaacaag atggtataat agctggctta
    27421 ggtgtattta agagagtttt tgagatactt ggtgatgtag atgtaaaatt atataaaaat
    27481 gatggtgata gagtaaagaa tcgtgaaaag atagctgtat taacaggtag tactagaaac
    27541 ttacttgtag gagagcgtgt agcattgaat tatttacaga gaatgagtgg tatagctact
    27601 attacaagta ggtatgttga aaagcttgaa ggtacaaata caaaattatt agatagtaga
    27661 aaaacgatac ctaatcttag aatattagat aagtattctg ttaaagtagg tggaggatgc
    27721 aatcatagat ttaatttatc tgatggaata ttgcttaaag acaaccatat tggggctgct
    27781 ggtagtgtta agaaggcagt tgaattagct agaaaaaata cttcttttgt tagaaagata
    27841 gaagtggaag tggaaacttt agacatggta aaagaagcaa tagaagctaa tgcagatata
    27901 ataatgttgg ataatatgag tttggaaatg gcaaaacaag cagtagatat tataaatgga
    27961 agagccattg tagaattttc cggaaatgta aatttagata ctatagaaga tataggaaaa
    28021 attggtgtgg atgttgtttc tgtaggagcg cttacacatt ctgttaaagc tctcgatata
    28081 agtatgaaga atttgagaaa tatataagtt ttatattgaa ataaacttaa ttaaaataga
    28141 ctccttaaat ttgttttata aatttaagga gtctattttt tattcattaa aattaataaa
    28201 aatataaaaa aatcaatca
//
LOCUS       DAMJYN010000048        28073 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.049, whole genome shotgun sequence.
ACCESSION   DAMJYN010000048 DAMJYN010000000
VERSION     DAMJYN010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 28073)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28073)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28073
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.049"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(58..1698)
                     /gene="bclA2"
                     /locus_tag="PC466_002268"
     CDS             complement(58..1698)
                     /gene="bclA2"
                     /locus_tag="PC466_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like exosporium glycoprotein BclA2"
                     /protein_id="HDF2769646.1"
                     /translation="MSDISGPSLYQDVGPTGPTGATGPTGPTGPRGATGATGANGITG
                     PTGNTGATGANGITGPTGNMGATGANGTTGSTGPTGNTGATGANGITGPTGATGATGA
                     NGITGPTGNKGATGANGITGPTGATGATGANGITGPTGNTGATGANGATGLTGATGAT
                     GANGITGPTGATGATGANGVTGATGPTGNTGATGPTGSIGATGANGVTGATGPIGATG
                     PTGAVGATGPDGLVGPTGPTGPTGATGANGLVGPTGPTGATGANGLVGPTGATGATGV
                     AGAIGPTGAVGATGPTGADGAVGPTGATGATGANGATGPTGAVGATGANGVAGPIGPT
                     GPTGANGVAGATGATGATGANGATGPTGAVGATGANGVAGPIGPTGPTGANGTTGATG
                     ATGATGANGATGPTGATGATGVLAANNAQFTVSSSSLGNNTLVTFNSSFINGTNITFP
                     TSSTINLAVGGIYNVSFGIRAILSLAGFMSITTNFNGVAQNNFIAKAVNTLTSSDVSV
                     SLSFLVDARAAAVTLSFTFGSGTTGTSPAGYVSVYRIQ"
     gene            complement(2076..2615)
                     /gene="hpt"
                     /locus_tag="PC466_002269"
     CDS             complement(2076..2615)
                     /gene="hpt"
                     /locus_tag="PC466_002269"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HDF2769647.1"
                     /translation="MDIETKKWEVLYSEEKIKDKLRELGAIIEKDYKDKNLMVVSLLK
                     GSFIFCADLVRNINLPLRVNFMTTSSYGNNEESTGKVKVVSDVTTDIAGYDVLVVDDI
                     TDSALTMDFVLKHLKAKNPASLKCCVLLDKPSRRKVDLVPDYCGFEIEDKFVVGYGFD
                     FGDYYRNVPYIFNVTDEDR"
     gene            complement(2943..4250)
                     /locus_tag="PC466_002270"
     CDS             complement(2943..4250)
                     /locus_tag="PC466_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine dehydratase subunit alpha family protein"
                     /protein_id="HDF2769648.1"
                     /translation="MRDIRKELVEMLKAEVKPAVGCTEPVALALACAKAKELLGEEIV
                     ENRMLVSPSIYKNGMCVGIPGTERLGLKIAAALGIVGGHSENGLSVLETLTKEEVKIA
                     EDYMDNTPLSITPADTREKVFIEVVLKGKNHIAKVRIRTKHDNFTFLEKDGEVLLDNE
                     PKVSASNDAAEKAESLMDTVTIQELIKNVEEIDFKDIEFLLDGVKMNEEMAEYGLKQK
                     TGIGVGYGIKKSIEEGLLGNDVINYAMMLTAGASDARMAGVKMPVMSSNGSGNHGLTA
                     ILPIVAYNKKFPQSDEKLAKALAISHLVTGYIKNYTGRLSAVCGCGVAASTGATAGIS
                     WLMNGTEKQIEGAIENMIADLSGMICDGAKAGCALKLSSAASAAIQSAIIAKQDCFVP
                     PLNGIVGSSVEQSIQNLGRVSDKGMSITDEIILNVMNDMNKVD"
     gene            complement(4675..6450)
                     /locus_tag="PC466_002271"
     CDS             complement(4675..6450)
                     /locus_tag="PC466_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2769649.1"
                     /translation="MMVMIGLEYIKSDIQNIAEAIVSVLNIDVTIVNKELFRIAGTGV
                     YIDKIGEKVDKYTAFKKSLTEQITILIDDPKSSDVCRECYKSGACVEFAEVCCPIICD
                     GDSHGVIGLIAFTKEQAQIIENNKSGLINFLGKMADLISNKLKAQIKTYELELEKKKL
                     ETLLNNMDKAVVSIDVDGKIDKYNSKFKELFNIKDSITGKNIFVELDFIKKPSINNFK
                     KDKSCSFFYKRYGYDSKGIYNINKIVLKNELKGYVIDFIDKRDAIKNYNKMNKDYRIK
                     LENIIGESVAIRNSKKEALIASKSTSTVLITGESGTGKELFARAIHNHSNRVDNPFIA
                     VNCAAIPDNLLESELFGYEEGAFTGAKKGGKLGMFEVAHKGSIFLDEIGDMSLHLQSK
                     LLRVLQEKELNKIGSKSNVSIDVRIIAATNKDLEKMVQNGTFREDLYYRLNVIPIKLP
                     SLRERKEDIPLIIKHMVKEYSKKLDKNVIDIDSRVVDAMMEYKWPGNIRELQNIIEYS
                     VNMSSSSIITMNVIPQKIKNTSVEELEVKSDRIIPLDELEKIEIIKALNKYKDYKKDK
                     ELTAKALGISRATLYRKIEKYNIIS"
     gene            complement(6447..6584)
                     /locus_tag="PC466_002272"
     CDS             complement(6447..6584)
                     /locus_tag="PC466_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769650.1"
                     /translation="MEINYELIIIVMLFVILMSIQFTLNKIYLILKEIRQILMLKKNK
                     E"
     gene            complement(6662..7231)
                     /locus_tag="PC466_002273"
     CDS             complement(6662..7231)
                     /locus_tag="PC466_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HDF2769651.1"
                     /translation="MKSILCQINKQPVKAKYTSDELECFLDTIEYNVGDKILLVGHIG
                     NLGKRLRGLGTSVTILENSNYEDVCYSLVYNENCNVVKGKLEFLPFDDNQFNKIIIVD
                     QFNVITDCEKASSEIQRVLKGNGEVILEDLNLKNLKVKLNYLKHKFCGSVAKIHYPHE
                     VFNIFSRLNFDGMIKESNKLKYIYVGKRR"
     gene            complement(7415..8050)
                     /locus_tag="PC466_002274"
     CDS             complement(7415..8050)
                     /locus_tag="PC466_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HDF2769652.1"
                     /translation="MIAVKDENNVVNLRGELDNKLEFSHEIFGEKFYNMKIKINRLSD
                     SFDILPMTVSERLLQDIDLDKQNLVNVVGQLRSYNKTLNNKNRLVLTVFVREIKSIDE
                     ENKDPNSIFLDGYVCKEPVYRKTPLGREITDLLVAINRPYNKSDYIPSIVWGRNAKFA
                     KNLKVGDRIQLWGRVQSREYEKKIDENNVVKKMAYEVSISKIKKLDENNNE"
     gene            complement(8718..9599)
                     /locus_tag="PC466_002275"
     CDS             complement(8718..9599)
                     /locus_tag="PC466_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TSUP family transporter"
                     /protein_id="HDF2769653.1"
                     /translation="MVAILKALYVVFAAIFAVVFGKDVAKANKEGKLEEQSTPKVAVT
                     GFITDFFDTLGIGSFAPTIAMSKALKLNIPDKKMPGTLNVAHTIPVVTEAFIFTSIIP
                     VDGVTLVSMVVAAAVGSYIGAGIIAKMDERKIQLVMGVTLALTAILMLLGHPWINVLP
                     GGGNELGLTGVKLVIGVIGNFILGALMTAGIGLYAPGMAMVYFLGMSAKVAFPIVMGS
                     CALLMPVASMKFIKEDAYTKKASVIIAICGLIGVFVAAYIVKTLPMDILKALVIVVIA
                     YTSATMIMAANKNKKTA"
     gene            complement(9719..10726)
                     /locus_tag="PC466_002276"
     CDS             complement(9719..10726)
                     /locus_tag="PC466_002276"
                     /EC_number="5.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline racemase"
                     /protein_id="HDF2769654.1"
                     /translation="MKFSRSIQAIDSHTAGEATRIVVGGIPNIKGNSMPEKKEYLEEN
                     LDYLRTAIMLEPRGHNDMFGSVMTQPCCPDADFGIIFMDGGGYLNMCGHGTIGAMTAA
                     IETGVVPAVEPVTHVVMEAPAGIIRGDVTVVDGKAKEVSFLNVPAFLYKEGVEVDLPG
                     VGTVKFDISFGGSFFAIIHASQLGLKIEPQNAGKLTELAMKLRDIINEKIEIQHPTLA
                     HIKTVDLVEIYDEPTHPEATYKNVVIFGQGQVDRSPCGTGTSAKLATLHAKGELKVGE
                     KFVYESILGTLFKGEIVEETKVADFNAVVPKITGSAYITGFNHFVIDEEDPLKHGFIL
                     K"
     gene            complement(10746..11228)
                     /locus_tag="PC466_002277"
     CDS             complement(10746..11228)
                     /locus_tag="PC466_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase"
                     /protein_id="HDF2769655.1"
                     /translation="MSFVGISTSMKNTSLHIFRDPLLDLIDNDSDIDLLGVVVVGTSE
                     HNEWKTFLATRLGRWIESLRPDGVIITLDMAGNQHIDFTNAIAEFVKSDIPAVGLTIM
                     GADGLVITNPYLDKATIIDYKKTTGYIETEVVGDNHMDEVDVKKALAFLKLKMRKDAK
                     "
     gene            complement(11246..11713)
                     /locus_tag="PC466_002278"
     CDS             complement(11246..11713)
                     /locus_tag="PC466_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase"
                     /protein_id="HDF2769656.1"
                     /translation="MGIGPSTKETSLHHFRDPLLDIVESDKDVDLLGVIVVGTPDGNE
                     NKTFVGQRTAAWLEAMRVDGAIVSSDGWGNSHVDYANTFEEIGKRDIPVVGVTFNGTQ
                     AKFVVSNQYMDTIVDMNKSKEGIETEVVGENNTNEIDAKKALAFLKLKMRKHG"
     gene            complement(11728..12486)
                     /gene="prdD"
                     /locus_tag="PC466_002279"
     CDS             complement(11728..12486)
                     /gene="prdD"
                     /locus_tag="PC466_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase cluster protein PrdD"
                     /protein_id="HDF2769657.1"
                     /translation="MEEKIMRRLVIKPFHMNEVNFGSKTSIKKDVLTIDLSSIDEIKE
                     REELITDIKVDIIKPGDYDREINTIMDIIPISTKVLGRLGEGITHTLTGVYVMLTGAD
                     EDGNQMHEFGSSEGILKDQMVFGRYGTPSVEDYIIHVDVTLKGGLPFERTLPLAAFRA
                     CDDFIQEIRASLKMEDGRNATQVREYFDKIRPNAKKVVIVKQIAGQGAMYDNQLFSKE
                     PSGFEGGTSIIDMGNVPMIISPNEYRDGALRAMT"
     gene            complement(12566..13291)
                     /gene="prdB"
                     /locus_tag="PC466_002280"
     CDS             complement(12566..13291)
                     /gene="prdB"
                     /locus_tag="PC466_002280"
                     /EC_number="1.21.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:complement(12839..12841),aa:Sec)
                     /transl_table=11
                     /product="D-proline reductase (dithiol) protein PrdB"
                     /protein_id="HDF2769658.1"
                     /translation="MSLTTVQGLQSEIFVPITPPPVWTPVTKELKDMTIALATAAGVH
                     LKSDKRFNLAGDTTFRAIPNTATVDEMMVSHGGYDNGDVNKDINCMFPIDRLHELAAE
                     GFIKGVAPMHYAFMGGGGNQHVFTEETGPAIAAKLKEEGVDGVVMTAGUGTCHRTAVI
                     VQRAIEEAGIPTIIIAALPPVVRQNGTPRAVAPLVPMGANAGEPHNIEMQTHILRDTL
                     EQLVAIPSAGKIVPLPYEYKAHV"
     gene            complement(13329..13613)
                     /locus_tag="PC466_002281"
     CDS             complement(13329..13613)
                     /locus_tag="PC466_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769659.1"
                     /translation="MDRLKYISSETFYEGIIVDIKGGGVTIDLKGRLGQFKIPNRMLI
                     TDYELKIGQEVGFMLSYPEVLSPEPNQEYVENIRREKEKQAEMQSKQEEK"
     gene            complement(13694..15574)
                     /gene="prdA"
                     /locus_tag="PC466_002282"
     CDS             complement(13694..15574)
                     /gene="prdA"
                     /locus_tag="PC466_002282"
                     /EC_number="1.21.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-proline reductase (dithiol) proprotein PrdA"
                     /protein_id="HDF2769660.1"
                     /translation="MSITLETAQAHANDPAVCCCRFEAGTIIAPENLEDPAIFADLED
                     SGLLTIPENGLTIGQVLGAKLKETLDALSPMTTDNVEGYKAGEAKEEVVEETVEEAAP
                     VSEAAVVPVSTGVAGETVKIHIGEGKNISLEIPLSVAGQAGVAAPVANVAAPVASAAA
                     EVAPKVEEKKLLRSLTKKHFKIDKVEFADETKIEGTTLYIRNAEEICKEANETQELVV
                     DMKLEIITPDKYETYSEAVLDIQPIATKEEGELGSGITRVIDGAVMVLTGTDEDGVQI
                     GEFGSSEGELNTTIMWGRPGAADKGEIFIKGQVTIKAGTNMERPGPLAAHRAFDYVTQ
                     EIREALKKVDNSLVVDEEVIEQYRREGKKKVVVIKEIMGQGAMHDNLILPVEPVGTLG
                     AQPNVDLGNMPVVLSPLEVLDGGIHALTCIGPASKEMSRHYWREPLVIRAMEDEEIDL
                     VGVVFVGSPQVNAEKFYVSKRLGMLVEAMEVDGAVVTTEGFGNNHIDFASHIEQIGMR
                     GIPVVGVSFSAVQGALVVGNKYMTHMVDNNKSKQGIENEILSNNTLAPEDAVRIMAML
                     KNAIEGVEVKAPERKWNPNVKLNNIEAIEKVTGEKIVLEENEQSLPMSKKRREIYEKD
                     EN"
     gene            complement(16003..17763)
                     /gene="prdR"
                     /locus_tag="PC466_002283"
     CDS             complement(16003..17763)
                     /gene="prdR"
                     /locus_tag="PC466_002283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54 dependent transcriptional regulator
                     PrdR"
                     /protein_id="HDF2769661.1"
                     /translation="MFSIPEVKKVEEVMDTKFTTIDEDTRIEDAIKEMIKSNTKTLMV
                     IDSSDQLKGIISMTDIHNLYEMHKKYEGQPVKLIMKKDVIYVNEGLTLDECRDIMILK
                     NIGILPVLRDNKIIGVLKQEHIRDYLYMHLEDYGLTLKYIIGQIKEGICAINNEGVVI
                     LWNKFMEERYDIKSEDIVGRPMNEFLENTISEKVLNSKVGMSDLYFTDKKENMYALVH
                     ANPIFYKEEFIGVVCTEVDVTEAKILALELEKVNDTLKYLKNEVKNLSKGSFDKILGK
                     SYKLEKSKAIAKQVARTNSSIFIWGESGTGKEVFARAIHDYSERKGQFIPVNCSAIPN
                     ELFESEFFGYESGAFTGASKKGRIGIFELAKDGTVFLDEIADLPLSMQAKLLRVLQEK
                     EIRRVGGDTTIKINPRIISATNKDLSKMVKAEKFREDLYYRLNVVEIKIPPLRERKED
                     IGLLVHSFLEEICKQNNKPVLTISKDVIDIFQNYRWKGNIRELKNTIENIVVLSQNSK
                     IDVDDVPSYMMDSTNNSTEEEEYPLDLTKATQKIEIKNITKALKMSNGNKAKAAKILN
                     IPRTTLYYKIDQYKIDVSKI"
     gene            complement(18233..18395)
                     /locus_tag="PC466_002284"
                     /pseudo
     CDS             complement(18233..18395)
                     /locus_tag="PC466_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011020315.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(18564..19877)
                     /gene="prdC"
                     /locus_tag="PC466_002285"
     CDS             complement(18564..19877)
                     /gene="prdC"
                     /locus_tag="PC466_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase-associated electron transfer
                     protein PrdC"
                     /protein_id="HDF2769662.1"
                     /translation="MNKLYSILLKQHVGGPDKPVVSVGDVVKKGTLIAEPTGLGANIY
                     ASVSGKISEINDQAIVIEADEVQEDTFEPLKGEGILDLIKEAGVVGMGGAGFPTHVKL
                     NIDLNGGTILANAAECEPLLAHNIKEIEERPEIVYQGIKYAMEVTNAGKGMLAIKSKH
                     PKAIEAFKKVIKPGDNIEVAELVDMYPMGEERAIVRDVLGKLLEPTQLPSEANAVVIN
                     VETLTRIVEAVEQKRPVISKNITVVGQLNSGKESIVFEDVPIGTTVGELIERAGGIKG
                     EYGEIILGGPFTGKATTLDAPITKTSGGIIVTMPFVNEKRKMGLLVCACGPNEERMRD
                     IATKMGVTDIVSVQKCKQAQEIKGALKCENPGHCPGQAQKCIEFKKAGAEVILIGNCT
                     DCSNTVMGSAPKLKLGVYHITDHVMRTVNHPLIRRIKGDVRLKIK"
     gene            complement(20266..21030)
                     /locus_tag="PC466_002286"
     CDS             complement(20266..21030)
                     /locus_tag="PC466_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HDF2769663.1"
                     /translation="MKREVKRTKALIYSVLFFSLLLVLIFVFVYGIKYICSKYDNSKM
                     PIYKVDTNEKKIALSFDVAWGTDNMDDILKILDKHNVKATFFLVGSWVDDNEEIVKAI
                     DEKGHEIGNHSNTHANLKEISKEDITKEIETTSEKIYNITGKKTNLFRPPFGDVNNKA
                     MDICSDLGYKVIKWDVDSIDWKELGPNHVIEKVIKESQPGSIVLFHANINDVDNYLDT
                     IISRLKKDGYSLVKISDLLYKDNYVVDSNGVQKTKN"
     gene            21321..21524
                     /locus_tag="PC466_002287"
     CDS             21321..21524
                     /locus_tag="PC466_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta-type small acid-soluble spore
                     protein"
                     /protein_id="HDF2769664.1"
                     /translation="MSNSNRTVVPEAKAALNQMKLEIANEIGLSNYENIDKGNLTARE
                     NGYVGGYMTKKLVEMAERQMAGK"
     gene            21714..22250
                     /locus_tag="PC466_002288"
     CDS             21714..22250
                     /locus_tag="PC466_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4364 family protein"
                     /protein_id="HDF2769665.1"
                     /translation="MFENSSEELAYHKLLILYILEKIKMDLTNSQITQVVLETEMMNY
                     FSLQQLLSQLMESKFLTTYKDSDREYYALTQRGVESLEYFFNRIPTSVTEKIDKYIDS
                     NKENLLADTQVKSSFVKQSDNEFIVNLRVIENQSNLIDLNLNVSSEKQAKLICNNWKN
                     NASYMYAEVIDLLIRDIH"
     gene            complement(22254..23120)
                     /locus_tag="PC466_002289"
     CDS             complement(22254..23120)
                     /locus_tag="PC466_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YncE family protein"
                     /protein_id="HDF2769666.1"
                     /translation="MKIYISNYLSKSISIVDYSTLELEKEIVLEDNIYPHHFCIEKEK
                     NLIYIPSSSNGILYVLDLSNDKIIDTVSIGGSLSQVVLSDNELFVANEDSNSIYVLDK
                     NTLNPIGIIGVDNMPHGFDFDRESKKLYVPCINSIVCIDTINKNIQKKINMDFRAWHI
                     ELDKQKKEMYISTLDGKLIIIDEVSMDIKKVLYEFLLPVEIRFNYSGKKVYVADLGYN
                     NVRILDYTTSRYIGNIEINGIPQGLEISKDEKLLFVSDTQENSVKVYETANNKLIKEI
                     KVGKEPTTIICL"
     gene            23268..23513
                     /locus_tag="PC466_002290"
     CDS             23268..23513
                     /locus_tag="PC466_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03905 family TSCPD domain-containing
                     protein"
                     /protein_id="HDF2769667.1"
                     /translation="MKVTFNPSGVCCREMIFEVDENNVIVDAEFIGGCNGNLSGLRSL
                     IIGQNALEVADKLNGIDCGGKGTSCPDQLSKAIRQSI"
     gene            complement(23627..24925)
                     /locus_tag="PC466_002291"
     CDS             complement(23627..24925)
                     /locus_tag="PC466_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HDF2769668.1"
                     /translation="MKYEEALEYISQTNKFGIRLGLENIGKLLELLGNPQETLNIIHV
                     AGTNGKGSVCSFVSNILRECGYKVGLYTSPYLETFTERIRVNGQNIPQDDVARIIELI
                     KEKIEIMVKEGYAYPTEFEVVTAMAFYYYSEQKVDFVALEVGLGGRYDATNIITKSLV
                     SVIVSISLDHTGILGDTIEKIAYEKAGIIKENGVVLVYDQTDEAKDVIKSVCKEKKAK
                     YIEVDFDDINIKKSDINSQIYDCTVMKETYRDLEIKLIGEHQINNSILAISVIKYLKD
                     INKLANINEESIRKGLINTKWPGRIEKIKENPIFIIDGAHNEDGAKSLAKALDKNFKG
                     RKLTLLIGMLEDKDIDSVLEILLPHFNKVITTTPNNPRAINSDILREKVLKYVDDVTS
                     KHEIEDAVNYTLETSSEDDIIISAGSLYMIGTVRTLVKKL"
     gene            complement(25058..26089)
                     /locus_tag="PC466_002292"
     CDS             complement(25058..26089)
                     /locus_tag="PC466_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HDF2769669.1"
                     /translation="MENICDMNNKVKVAVLDTGIDKEHDYLKDNLVGGIAFECMHDYI
                     FISDKFDDEDGHGTACASIIKKEYEDVELFVIKILRKDGITNIKVLEEALRYLLDTNI
                     RLINLSLSVIGVESVKGLFEVCYELFRKGKIIVCSLANDFDLSYPAMFNNVIGVRGFT
                     LDGDDSFWYNKKYDVQCVMDSNSYISCDINNSYRLPPKCNSYLSAKLTGKIAKILSEK
                     PGITISDLNDKLESLATRNHWDSCDFDECSRIVNFKLDLYDKENALLMKVADVVRDCL
                     DIEDNNEKLFKGSLFNKEIGLVYDNCFNLLKKLEHRFDIKFNYMDISKYDLVSIYTLT
                     ELVERYKNL"
     gene            complement(27135..27845)
                     /gene="rgaR"
                     /locus_tag="PC466_002293"
     CDS             complement(27135..27845)
                     /gene="rgaR"
                     /locus_tag="PC466_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RgaR"
                     /protein_id="HDF2769670.1"
                     /translation="MFRVVICDDEKIQRSILKEFTKKLLSERCLNYQILEFSCGEDLI
                     SKYPEKIDIIFLDIQMKDINGIEVAKKIRKFDEKVEIIFTTAFSEYAPQGYEVRAYRY
                     LVKPIEYSNFAMGVNLCIDNLQRKKERYIVLNSKKGFNRILIDSILYVETVKRDLVVH
                     TIGRDYKANMSMKQAEKLLCENGFFRCHTSFIVNLRRIEDLRDNMITINEQFIPISKY
                     RLKDLKVALTSLLCDIMY"
BASE COUNT         8563 a         5212 c         3124 g        11174 t
ORIGIN      
        1 tttattggta tatgaaatca tattgtttat tattttataa tcttttcatc atataaacta
       61 ttgtattcta taaactgata catacccagc tggagaagta cctgtcgtgc ctgaaccaaa
      121 tgtaaagctt aaagtaacag ctgctgctct agcatcaact aaaaagctta aacttacact
      181 tacatctgat gaagtaagcg tatttactgc ttttgcaata aagttatttt gggctactcc
      241 attaaagtta gtagtaattg acataaatcc tgcaagtgaa agtatggcac gtataccgaa
      301 agatacattg tatatccctc caactgcaag atttatagta ctacttgttg gaaaagttat
      361 attagttcca tttataaatg atgaattaaa tgtcactaat gtattattcc ctaaacttga
      421 agaagatact gtaaattgtg cattgtttgc tgctaacact cctgttgctc cggtcgctcc
      481 tgttggacct gttgctccat ttgctcccgt tgctccggtc gcccctgttg ctccggtcgt
      541 tccatttgct cctgttggtc ctgttggacc tattggacct gctactccat ttgctcccgt
      601 tgctcctact gctcctgttg ggcctgttgc tccatttgcc cctgttgctc cggtcgctcc
      661 tgttgctcct gctactccat ttgctccggt tggacctgtt ggacctattg gacctgctac
      721 tccattcgct ccagttgctc ctactgctcc cgttgggcct gttgctccat ttgcccctgt
      781 tgctccggtt gctccggttg gacctactgc tccatctgct cccgttgggc ctgtcgctcc
      841 tactgctccg gttggaccta ttgccccagc tactcctgtt gctccggtcg ctcctgttgg
      901 acctaccaaa ccatttgctc cggttgctcc ggttgggcct gttggaccta ccaaaccatt
      961 tgctccggtt gctccggttg ggcctgttgg gcctgttgga cctaccaaac catctggacc
     1021 tgttgctcct actgctccgg ttggacctgt tgctcctatt ggacctgtgg cacctgttac
     1081 tccatttgct cccgttgctc ctatacttcc ggttggacct gttgctcctg tatttcctgt
     1141 tgggcctgta gcacctgtta ctccatttgc tcccgttgct cctgttgctc ctgttggacc
     1201 tgttatccca ttcgctcccg ttgccccagt tgctccggtt agtccggttg caccatttgc
     1261 tcccgttgct cctgtatttc ctgttggacc tgttattcca tttgctcccg ttgctcctgt
     1321 tgctcctgtt ggacctgtta tcccattcgc tcccgttgct cccttgtttc cggttggacc
     1381 tgttattcca tttgctcccg ttgctcctgt tgctcctgtt ggacctgtta ttccatttgc
     1441 tccagtcgct cctgtatttc ctgttggtcc tgtagaacct gttgttccat ttgctccagt
     1501 cgctcccata tttcctgttg gtcctgttat tccattcgcc ccggttgctc ccgtatttcc
     1561 tgttggtcct gttattccat ttgctccggt cgctccggtt gcgcctctag gccccgtcgg
     1621 tcctgttgga ccagtagcac ctgttggccc tgttggacct acatcttgat ataaacttgg
     1681 acctgaaata tcactcatat aattaatcct ccttttttaa agttagagta ttactctata
     1741 aatattgagt attactctat ataattatat gaatcgacaa tttcttatgt gataatgtat
     1801 ctatttgctt atatcaacat atatgctttg attcttaaat ttcattactt ttttgtaaaa
     1861 tcttttacaa ttattagtac tcttttacaa ttattaatac aattaaaaaa ctcatttccc
     1921 atcaattatt taaaattttt ttattatgtt ataaaaaata gataattaaa ttgcataaaa
     1981 ttaatttaat actactttaa ttacttttta aataaaaaaa cctcaacacg attaataaaa
     2041 atcatattaa ggcatccaca aaattatata attgcttatc tatcttcatc agtaacattg
     2101 aatatataag gaacatttct ataataatca ccaaaatcaa acccatatcc aaccacaaac
     2161 ttatcttcta tttcaaatcc acaataatct ggcactaaat caacttttct tctgcttggt
     2221 ttatccaaaa gaacacagca ttttaaacta gcaggatttt tagcttttag atgttttaac
     2281 acaaaatcca tagtaagtgc agaatcagta atatcgtcta caaccaaaac atcatatcct
     2341 gctatatcag tagtcacatc tgaaaccact ttaacctttc cagtactttc ttcattgttt
     2401 ccataactag atgtagtcat aaaattaact ctaagtggta aatttatatt tctaactaag
     2461 tctgcacaaa atataaagct accttttaat agagaaacta ccataagatt tttatcttta
     2521 taatcttttt ctataattgc tcctaattcc cttaatttat ctttaatttt ttcttctgaa
     2581 tacaatactt cccatttttt tgtttctata tccataaaaa gacctccaat tgtaataatc
     2641 cttcttaatt ttataagaga ttgctcactt tttcaatact cttattcaat attagtcaat
     2701 attattgagt ttttatgttc attcaacaat tattaacaat gtatcttata ttttaagtag
     2761 ttcatatatc cacactaaat tacatactat atattttaga caaaaaaaga aaaaacttgc
     2821 actaacaagt tttttctatt atacataaat ttatacataa tcatatttta ttagagggta
     2881 ctaattaaat ttatttatgc tatttttgtt atacctcata atacaaaaca tattataaag
     2941 tactagtcaa ctttattcat atcattcatt acatttaaga ttatctcatc tgttatagac
     3001 atacctttgt cacttactct acctaagttt tgtatacttt gctcaacact tgaaccaact
     3061 ataccattta gtggtggtac aaaacaatct tgcttagcta ttatagcact ttgtatagct
     3121 gcagatgctg cagaagataa ttttaatgca caaccagctt tcgcaccgtc acatatcatt
     3181 ccacttaagt cagctatcat attttctata gctccttcta tttgcttttc agtaccattc
     3241 ataagccaag agataccagc agttgctcca gtagaagcag caacaccaca tccacacaca
     3301 gcagataatc ttcctgtata gttcttaata taaccagtta ctagatgaga tatagctaaa
     3361 gcctttgcta gtttttcatc agattgtggg aattttttat tataagcaac gattggaaga
     3421 attgctgtta atccatgatt tccacttcca tttgaactca taacaggcat ttttacgcct
     3481 gccattcttg catctgaagc tccagcagtt aacatcattg cataatttat aacatcatta
     3541 cctaaaagac cttcttctat agacttttta attccatatc cgacaccaat accagttttt
     3601 tgttttaatc catattcagc catctcttca ttcattttta ctccatctag taaaaattct
     3661 atatctttaa aatcaatttc ttctacattt tttattaatt cttgtatagt tactgtatcc
     3721 attaaacttt cagctttttc tgccgcatca tttgaagctg atacttttgg ttcattgtct
     3781 aataatactt ctccatcttt ttctaagaac gtaaaattat catgtttagt tcttattctc
     3841 actttagcaa tatgattttt tccttttaac acaacttcta taaatacttt ctctcttgta
     3901 tcagcaggtg ttattgatag tggagtatta tccatataat cctcagctat tttaacttct
     3961 tcttttgtta gagtttctaa cacacttaat ccattttcag aatggccacc tactatacct
     4021 agagctgctg caatttttaa tcctaatctt tcagtacctg gtatacctac gcacatgcca
     4081 tttttgtaga tactaggact aactaacata cgattttcaa ctatttcttc tcctaataat
     4141 tcctttgcct ttgcacatgc tagagctaag gctactggtt cagtacaccc tactgctggt
     4201 ttaacttctg cctttaacat ttccactaat tcttttctta tatctctcat tatatataaa
     4261 cctcccaatt aagtttagat ttagtactca aataattaat taaataattt cttatctata
     4321 tttatagcaa aatacatgcc atatttttta tatcttttta tatttttagt cttatattct
     4381 ataaccattg gtatgactgc ttctatttat gtattttttt tatttacata gagtatttat
     4441 attctttaaa atggagaaac atatgacaat ttcgcaaaaa gacaaaaaaa agtctcagaa
     4501 tgagattcta tatcattttg agacggctca aatgtgttat tttttaactt ataaaaacca
     4561 ttttttaatt cataaaaaaa gattatgcaa aacacttata gtataagttt aaagctttct
     4621 ttaaagttat gaatttagaa aaatttaaat tttatatagc tttttattat attactatga
     4681 aattatattg tatttttcaa tttttctata taatgtagct cttgatattc caagtgcttt
     4741 agctgttaat tctttatctt ttttataatc tttgtactta tttaaagctt ttattatctc
     4801 aatcttctct agttcatcaa gtggaattat cctatcgctt ttaacttcta actcttctac
     4861 agaggtattc ttaatttttt gaggaattac attcattgtg attattgaag aagaagacat
     4921 attcacacta tattcaataa tattctgcaa ctctcttata ttccctggcc acttatattc
     4981 catcatagca tcaacaaccc tgctatctat gtcaataaca tttttatcta atttttttga
     5041 atactcttta accatatgct tgattataag tgggatatct tcttttctct ctcttaaact
     5101 tggtaatttt ataggtataa catttaatct ataatataaa tcttctctaa aagtgccatt
     5161 ttgaaccatt ttttctaaat ctttatttgt agcagcaata attcttacat ctattgagac
     5221 atttgattta cttccaattt tattaagttc cttttcttgt aatactctca ataactttga
     5281 ctgtaaatgc aaactcatat ctcctatttc atctaaaaat atacttccct tatgagctac
     5341 ttcaaacatt ccaagctttc cacctttttt agctccagta aaagctccct cttcatatcc
     5401 aaataattca ctctctaata aattgtctgg tatagcagca cagtttacag ctataaaagg
     5461 attatctact ctattgctat ggttgtgtat ggctcttgca aatagctcct tacccgttcc
     5521 actttcccca gtaataagta ctgttgatgt tgatttagaa gctattaggg cttccttttt
     5581 agaatttctt atagctacac tttctccaat tatgttttcc aattttattc tataatcttt
     5641 attcatctta ttgtagtttt ttatagcatc tcttttatct ataaaatcaa taacatatcc
     5701 ctttaactca ttttttaata ctattttatt gatgttgtat attcccttcg aatcatatcc
     5761 gtatctttta taaaaaaaac tacacgattt gtctttctta aagttattta tagaaggttt
     5821 ctttataaaa tctaattcga caaatatgtt tttgccagtt atactatcct ttatattgaa
     5881 aagctcttta aattttgaat tatatttatc aatttttcca tccacatcaa tagacacaac
     5941 agctttgtcc atattgttta atagtgtctc taattttttc ttttctaatt caagctcata
     6001 agttttaatt tgtgctttta atttattaga tattaagtct gccattttgc ctaaaaagtt
     6061 tataagacca cttttattat tttctataat ttgtgcttgt tcttttgtaa aggctataag
     6121 gcctataacg ccatgagaat cgccatcaca tataatagga caacacacct ctgcaaactc
     6181 tacacaagcc ccacttttat agcattccct acatacatca ctactctttg ggtcatcaat
     6241 tagtattgtg atctgttctg taagtgattt tttaaaagcc gtatatttat ctactttctc
     6301 acctattttg tctatatata ctcctgtacc tgcaatccta aataactcct tatttactat
     6361 agttacatct atattgagta ctgatactat agcttcagct atattttgaa tatcagattt
     6421 tatatattct aaacctatca taaccatcat tccttatttt tctttaacat aagtatttgt
     6481 cttatttctt taagaatcaa gtatatctta tttaaagtaa attggattga catcaggatt
     6541 acaaagagca taacaattat tattaactca taatttattt ccatctaaac atctccttat
     6601 aacaaaagac taggcttaac ctagtctttt atattatatc catatttata ttttaactca
     6661 tttatcttct ttttcccaca taaatatatt ttaatttatt tgactcttta atcataccat
     6721 caaagtttaa tcttgaaaat atattaaata cttcatgtgg atagtgaatc tttgcaacag
     6781 aaccacaaaa tttatgttta agataattta acttaacttt taaattcttt aaatttaaat
     6841 cctctaatat aacctctcca ttgcccttta acactctttg tatttcagat gaagcttttt
     6901 cacaatctgt aataacatta aattggtcaa ctattattat cttgttgaac tgattatcat
     6961 caaatggtag aaactctaac ttacctttaa ctacattgca attttcatta tacactagag
     7021 aataacagac atcttcataa ttactattct ccagtatagt tacagaagtt ccaagacctc
     7081 tcaatctctt gcctaggttt cctatatgac caacaagcaa tattttatca cctacattat
     7141 actcaattgt atccaaaaaa cattctaatt catcagatgt atatttagct ttaactggct
     7201 gtttatttat ctgacataat atgcttttca caatgcttca cctcttcatt tcctcaatta
     7261 taaattatgt acagattaca ttataataaa tggcgagcaa ctattcaaga gatatttcat
     7321 tagtattttt ttaaacaatc tttatacatt ttaatatgat attataccaa atttattagg
     7381 attttattca taaaaatcag tctatttttt atgtttattc attgttattt tcatccaatt
     7441 tttttatttt cgatatggat acttcatatg ccattttttt gaccacatta ttttcatcta
     7501 tttttttctc atattctcta ctttgaaccc taccccaaag ctgtattcta tcaccaacct
     7561 ttagattctt tgcaaattta gcatttctac cccaaactat tgatggtata taatcagatt
     7621 tattataagg tctgtttata gcaactaata aatcggttat ttcccttcct aaaggtgtct
     7681 tcctatacac aggttcctta catacatatc catctaaaaa tatactatta gggtctttat
     7741 tttcctcgtc tatgcttttt atttctctga caaacactgt aagcactaat ctatttttat
     7801 tatttaatgt tttgttatat gatcttaatt ggcctacgac attgactaaa ttttgtttat
     7861 caaggtcaat atcttggaga agtctttctg atacagtcat tggaagtata tcaaaagaat
     7921 cgcttagtct gtttattttt attttcatat tataaaattt ttctccaaat atctcatggc
     7981 taaattctag cttattgtct aactcccctc ttaagtttac tacgttattc tcatctttaa
     8041 cagctatcat attttatccc tccacaattg ttaattctta tatttctggt atcagcttat
     8101 ataataaata tatttataag ggatgtattt tattacaaat ctttgattgc tgtttaaaag
     8161 tttttattta gttataaatt tcatttaata tttcactttt ataattataa aattattatc
     8221 tttttgtact acatatacta attaaactac ctatttcagt tttgtattaa ttataaaaat
     8281 cctattatat aattaataag tcatatataa cttaaattta ttcactctat ataagcaact
     8341 tcaacgaatt aaatttattc aaataattca gatgaatatt gagtcattat aaacttattt
     8401 ttcttaatta taagttatat tagacttatt acagcttata tttttattaa tctgtattaa
     8461 tatatgaaca tttattgaac ttattgatta taaaatttaa atatttagct ttaaattatg
     8521 ctttattctt tgaaaataca acgtttttta cattaaatct actaaatcac tatatatatt
     8581 acataattgg catgttaatt gctttatatt aatttagcaa ataaaaaact gccctaaaat
     8641 attaattcaa tattttaaag cagtttataa tctttattat tagctgtaat atttaataaa
     8701 cactaagtag tctttaacta agcagtcttt ttgtttttat ttgcagccat tatcattgta
     8761 gcagaagtat aagctataac tactattact aatgctttta atatatccat tggtagagtt
     8821 tttactatat atgcagctac gaaaactcct attaaaccac atatagctat tataactgat
     8881 gcttttttag tatatgcatc ttcttttata aatttcatac ttgcaactgg cattaataat
     8941 gcacaagaac ccataactat tgggaatgca acttttgcag acattcctaa gaaataaacc
     9001 attgccatac ctggagcata tagacctata ccagctgtca ttaaagctcc tagtataaag
     9061 ttacctatta cacctattac caatttaaca ccagtaagac ctaattcatt tcctccacct
     9121 ggtaatacgt taatccaagg atgacctaat aacattaata ttgctgttaa tgctaaagtt
     9181 acacccataa caagttgtat ttttctctcg tccatcttag ctattattcc tgcacctata
     9241 tatgaaccaa ctgctgctgc cacaaccata gatactaaag taacaccatc aactggtatg
     9301 attgatgtaa atatgaatgc ttctgtaaca actggaatag tatgtgctac gtttaatgta
     9361 ccaggcattt ttttatctgg tatatttaac tttaaagcct ttgacattgc tattgttgga
     9421 gcaaatgacc ctattcctaa tgtatcaaag aagtctgtta taaatcctgt tacagcaact
     9481 tttggagtac tttgttcttc tagtttcccc tctttgtttg ctttagctac gtctttacca
     9541 aacacaactg caaagattgc tgcgaatact acatataatg cctttaagat tgctaccata
     9601 atccatcctc ctattttttt attttttcat atattctgaa tcttatagcc taaaagctat
     9661 agaatagcaa ccgacaagtg gctactattc tattttaatt tcctaattta tttattactt
     9721 atttaagaat aaatccatgt ttaagtgggt cttcttcatc tattacaaaa tgattaaatc
     9781 cagttatata agcagaacca gttattttag gtactacagc attgaaatct gcaactttag
     9841 tttcttcaac tatttcacct ttgaataaag ttcctaatat actttcatat acgaattttt
     9901 ctcctacttt taattcacct ttagcatgta aagtagctaa tttagcactt gttccagttc
     9961 cacatggaga tctgtcaact tgaccttgac caaatataac tacatttttg taagtagctt
    10021 ctggatgagt tggctcatca tatatttcaa ctaagtctac agtttttata tgagctaaag
    10081 ttggatgttg tatttctatt ttctcattta ttatatctct aagtttcata gctagttcag
    10141 ttaatttacc agcattttga ggttcgattt ttaaacctaa ttgacttgca tgtattatag
    10201 caaagaagct tccaccaaat gatatgtcaa atttaacagt cccaacacct ggtaagtcaa
    10261 cttcaacacc ttctttatat aagaaagctg gtacgtttaa gaatgatact tctttagctt
    10321 ttccatctac aactgtaacg tctcctctta ttattcctgc tggagcttcc ataactacat
    10381 gagttacagg ctctactgct ggaactacac ctgtttctat agctgctgtc atagctccta
    10441 ttgtaccatg gccacacatg ttaaggtatc caccaccatc catgaagatt attccaaagt
    10501 cagcatctgg gcaacaaggt tgagtcatta cagaaccaaa catatcatta tgtcctcttg
    10561 gctctaacat tatagcagtt cttaaataat ctagattttc ctctaaatat tcttttttct
    10621 caggcataga atttcctttt atgttaggta ttccacctac aactattcta gttgcttcac
    10681 ctgctgtatg agagtctata gcttgtatac ttctgctaaa tttcatatca aattccccct
    10741 taggtttatt ttgcgtcttt acgcattttt aattttagga aagccaatgc ttttttaaca
    10801 tcaacttcat ccatgtgatt gtctccaact acttctgttt ctatgtagcc tgttgtcttt
    10861 ttataatcaa ttatggtagc tttatccaaa tatggattgg taattactaa tccatctgct
    10921 cccataatag taagacctac tgcaggtata tctgatttta caaactctgc tatagcattt
    10981 gtaaaatcaa tgtgctggtt tcctgccata tctaaagtta taatcactcc atcaggtcgc
    11041 aatgattcaa tccatcttcc aagtctagtt gctaaaaatg ttttccattc attgtgctct
    11101 gatgtcccaa ctacaaccac tcctaacaag tctatgtcag aatcattatc tatcaaatct
    11161 agtaacgggt ctctaaatat atgaagtgat gtgtttttca ttgatgtaga aattcccaca
    11221 aaactcattc ccttacttaa attttttatc catgttttct cattttaagt tttaaaaatg
    11281 ctaaagcttt tttagcatct atttcatttg tgttgttttc tccaactact tctgtctcaa
    11341 taccttcctt tgatttgttc atatcaacta tggtatccat atattgattg cttacaacaa
    11401 acttagcttg agtcccatta aatgtaactc caactacagg tatatctctt tttcctattt
    11461 cctcaaatgt gttagcgtag tcaacatgtg agtttcccca accatctgat gaaactatag
    11521 ctccatctac tctcatggct tccagccaag cggccgttct ttgtcccaca aaggttttat
    11581 tttcatttcc atctggagtt cctactacta ttactccaag taaatctaca tccttatcac
    11641 tttcaactat gtctaaaagt gggtctctaa agtgatgaag agatgtttct tttgttgaag
    11701 gtcctattcc cataatatcc acctctctta agtcatagct ctaagggcac catctctgta
    11761 ttcattagga gatataatca taggtacatt tcccatatct ataattgatg ttcctccttc
    11821 aaatccacta ggttcctttg agaataactg attgtcatac atagcacctt gacctgctat
    11881 ttgttttact atgacaacct tttttgcatt tggtcgaatt ttgtcaaaat attcacgaac
    11941 ttgagtagca tttcttccgt cttccatttt caaagacgct cttatttctt gtataaaatc
    12001 atcacatgct ctgaatgctg caagtggaag tgttctttca aaaggtaaac ctccctttaa
    12061 agttacatct acatggatta tataatcttc aactgatgga gttccatatc tcccaaatac
    12121 catttggtct ttcaaaattc cttctgaaga accaaattca tgcatttgat ttccatcttc
    12181 atctgcacca gttaacatta catatacacc cgttaaagta tgtgtgatac cctctcccag
    12241 tctgcctaaa acttttgttg atattggtat aatgtccata atagtattaa tttctctatc
    12301 ataatctcca ggttttataa tgtctacttt tatgtctgtt attaactctt ctctttcttt
    12361 tatttcatct atacttgata aatctattgt aagtacatct ttctttatag aagtttttga
    12421 accgaaatta acttcattca tatgaaacgg ttttataaca agtcttctca ttattttttc
    12481 ttccataata tccacctttg ttcttaaaac ccctctccta accgtgtagg agaagggttc
    12541 tatattttca aatataaatt acattttaaa cgtgagcttt atattcgtat ggtaatggaa
    12601 ctatcttacc agcagatggt attgcaacta attgctctaa tgtatctctt aatatatgtg
    12661 tttgcatttc tatattatgt ggttcaccag cattagcacc cattggaact aatggagcaa
    12721 ctgctctagg agttccgttt tgtctaacta ctggaggaag agctgctatt attattgtag
    12781 gtattccagc ttcctctatt gctctctgca cgatcacggc agttctatgg caagtacctc
    12841 agccagctgt cataactaca ccgtctactc cctcttcctt aagtttagca gcgatagcag
    12901 gaccagtttc ttcagtgaag acatgttggt ttcctccacc acccatgaat gcatagtgca
    12961 taggagctac tcctttgata aatccttctg cagctaattc atgtaatcta tctataggga
    13021 acatacagtt tatatctttg tttacatctc cattgtcata tccaccatgt gataccatca
    13081 tttcatcaac tgtagctgta ttaggtatag ctctaaatgt agtatctcct gctagattaa
    13141 atctcttgtc agattttaaa tgaacaccag ctgctgtagc taaagctata gtcatatctt
    13201 ttaattcttt agttacagga gtccaaactg gaggaggtgt tattggaacg aatatttcag
    13261 attgaagtcc ttgtactgtt gtaaggctca tatatttcct ctcccttcta ttttcaaacg
    13321 attatttatt atttttcttc ttgttttgat tgcatttctg cttgtttttc tttttctctc
    13381 ctaatatttt ctacatactc ttgattaggc tctggactta atacctcagg atagcttagc
    13441 atgaatccaa cttcttgacc tatcttaagt tcgtagtcag ttataagcat tctattaggt
    13501 attttaaatt gtccaagtct accttttagg tctatagtca ctccaccacc tttgatgtca
    13561 actataatac cttcataaaa agtctctgat gagatatatt ttaacctatc cattataatt
    13621 ctacctctct atactgtttt aaacttggat ctaaatttat gttattgtct aaatcttagt
    13681 tagtatctaa attttagttt tcgtcttttt cgtatatttc tcttctcttc ttactcattg
    13741 gtagagattg ctcattctct tctaatacta ttttttctcc tgtaactttt tctatagctt
    13801 ctatgttatt taatttaaca tttggattcc attttctttc aggagcttta acttctacac
    13861 cttctatagc atttttaagc atagccatta ttctaacagc atcttctgga gctaaagtgt
    13921 tgttagataa tatttcattc tctatacctt gcttagactt attgttgtct accatgtgag
    13981 tcatgtattt attaccaaca actagagcac cttgaacagc tgagaaactt acaccaacta
    14041 ctggtatacc tctcatacct atttgctcta tgtgagatgc gaaatctata tggttgtttc
    14101 cgaaaccttc agtagttact acagctccat caacttccat agcttcaact aacataccta
    14161 atctcttaga tacatagaat ttctcagcat ttacttgtgg agaaccaaca aatacaacac
    14221 ctactaaatc tatttcttcg tcttccatag ctcttattac taatggctct ctccagtaat
    14281 gtcttgacat ttcttttgat gcaggtccta tacaagttaa tgcatggata ccaccatcta
    14341 atacttcaag tggagataat acaactggca tgtttcctaa gtcaacgttt ggttgagctc
    14401 ctaatgtacc aactggctca actggtaata ttaggttatc atgcattgca ccttgtccca
    14461 ttatttcttt tataacaaca actttctttt taccttctct tctgtattgc tctattactt
    14521 cttcatcaac tactaaagag ttgtcaactt tctttaatgc ttctcttatt tcttgagtta
    14581 catagtcaaa tgcacggtga gcagctaaag gtcctggtct ttccatgtta gttcctgctt
    14641 ttattgttac ttgacctttg atgaatattt cacctttgtc agcagcacct ggtctacccc
    14701 acattatagt agtatttaac tcaccttctg aagaaccaaa ttcacctatt tgaactccat
    14761 cttcatctgt accagttaat accattacag ctccatctat aactctagtt atacctgaac
    14821 ctaattcgcc ttcttcttta gtagcgattg gttgtatatc taatacagct tcactgtaag
    14881 tttcatattt atcaggagtt attatttcta acttcatatc tacaactaac tcttgagttt
    14941 cattagcttc tttacatatt tcttctgcgt ttctgatgta taaagtagtt ccttctattt
    15001 tagtttcatc agcaaattca actttatcta ttttaaagtg ttttttagtt aagcttctta
    15061 aaagtttctt ttcttcaact tttggagcta cttctgctgc tgcacttgcc actggagcag
    15121 caacgtttgc tactggagca gcaactcctg cttgaccagc tactgataaa ggtatctcta
    15181 agcttatgtt cttaccttca cctatgtgta ttttaactgt ttcacctgca actcctgtgc
    15241 ttactggaac tactgctgct tctgatactg gagctgcttc ttctactgtt tcttctacta
    15301 cttcttcttt agcctctcct gctttgtatc cttctacgtt atctgtagtc attggagaaa
    15361 gtgcatctaa agtttctttt aacttagctc ctagtacttg acctatagtt aatccatttt
    15421 ctggtattgt taataatcca gaatcctcta agtctgcaaa tattgctgga tcttctaagt
    15481 tttctggcgc tataattgtt cccgcttcaa atctacaaca acaaactgct gggtcatttg
    15541 catgggcttg agctgtttct aaagttattg acatagtata aaatacctcc ttacattatt
    15601 ttcttattta ttattttaaa tctcaattcc tcaacaggta accccttaac tgagaaatta
    15661 agtaaattaa aacctacata atttgttatg attaatatta tttttttctc actcaaagtc
    15721 actttatatt ataagcaatt cctatgccaa cttattaaca aaaagatttt ttctataata
    15781 gattcttcat ctatcgctat ttttagccaa atattatata aatatttatt taaaatatgt
    15841 tattttttgt atttgtaaac attttctcaa acaaaaaaag tgtcaattaa tcaacacttt
    15901 ttcatttttt ttaacacatc tatatacaca acacttatac aagtgttggc tttactaggt
    15961 tttaaattaa agtttatcat tttgtcaaaa tttagtcata tgtcatattt tagacacatc
    16021 tattttgtat tggtctatct tataatacaa agttgttctg ggtatattta atatcttagc
    16081 tgctttagct ttatttccat tagacatttt aagtgccttg gttatattct ttatttcaat
    16141 tttttgagtt gccttcgtta aatctaaggg atactcttct tcttcagtac tattatttgt
    16201 agaatccatc atataacttg gtacatcatc tacatctatt ttagaatttt gtgacaatac
    16261 aacaatattt tcaatcgtat tttttaattc tctaatatta cctttccatc tataattctg
    16321 aaatatatct attacatctt tgctaattgt aagaacaggc ttattatttt gtttacatat
    16381 ctcctctaaa aagctatgaa ccaataatcc tatgtcttct tttctctctc taagtggagg
    16441 aatctttatt tcaacaacat ttaatctata gtataaatct tctctaaatt tttctgcctt
    16501 taccatttta ctcaaatctt tattggtagc tgatattatt ctaggattta tttttattgt
    16561 ggtatctcca ccaactcttc ttatttcttt ttcctgtaat actctaagca actttgcttg
    16621 catactaaga ggtaaatcgg caatttcatc taaaaataca gttccatctt ttgcaagttc
    16681 aaatatacct attcgaccct ttttacttgc tcctgtaaat gcacctgatt catacccaaa
    16741 aaactcactt tcaaataact catttggtat ggcactacag ttaacaggta taaattgacc
    16801 ttttctctca ctataatcat gaatagctct tgcaaatact tctttacccg taccactttc
    16861 accccaaata aatatgctac tatttgttct agccacttgt tttgcaatcg ctttcgattt
    16921 ttccaattta taacttttac ctaaaatctt atcaaaacta cctttagata aatttttgac
    16981 ttcgttcttt agatatttta atgtatcatt tactttttca agttcaagag ctaatatctt
    17041 agcttctgta acatcaactt ctgtacatac aacaccgata aattcttctt tataaaatat
    17101 aggatttgca tgaactaatg catacatatt ttctttttta tctgtaaaat acaagtcact
    17161 cattccaact ttactattta gtactttttc tgaaatagta ttttccaaaa attcattcat
    17221 cggtcgacca actatatctt cagactttat atcatacctt tcctccataa acttattcca
    17281 caagataaca acaccttcgt tatttatagc acaaattcct tctttaattt gacctataat
    17341 atacttcaaa gtcaatccat aatcttctaa atgcatatat agatagtccc taatgtgctc
    17401 ttgttttaga actccaataa ttttattatc tctaagaaca ggaagaatcc ctatattttt
    17461 taatatcatt atatctctac attcatctaa ggttaaacct tcgttgacat atattacatc
    17521 cttcttcatt ataagtttta ctggttgacc ttcatacttt ttatgcatct cataaagatt
    17581 atgtatatcc gtcatggata taatgccttt taattggtca gatgaatcta ttaccattag
    17641 agtttttgtg ttgcttttta tcatttcttt tattgcatct tcaattcttg tgtcttcgtc
    17701 tatagttgta aattttgtat ccattacctc ttctactttt tttacttctg gtatcgaaaa
    17761 cataaagtcc ccccctttat agtagtacct catcaaaact tatttatata tatttattct
    17821 agcatattat aataattatt tattaaataa ttattattaa aatttattaa gtaattagca
    17881 tttaaattta tataatcact ttaaaattta taattaaatt tatacaaatg aaatcaaatg
    17941 aattataccc ttagtatatt attttttcaa tactattttc accttcaaaa catttttcta
    18001 ttcatcaaac aattaatgaa tgcctgtatc caatcataaa tttaagaata taattaaaat
    18061 agatattttt aaacaaacta tatttgcata ttatatttac ataaaaaagt cccaaaatga
    18121 cttataaatc aatttgagac tttttatttt aaacttaata ataatataaa ttaatttctt
    18181 tttataaatt aaggcgtaaa accactatac ctttaggttg gtggatgtaa acctatccct
    18241 tactttgtat gtatttttca atcatttctt tagaaacatt tcctacactg aaagcaaagt
    18301 atccatctga gcaaaaagtt ttttctgtat ttacatacaa atatcaaatg taccaataac
    18361 aaacacttag aatggtttct actaacataa ttcacaactc caattcaatc ccttcttaaa
    18421 tatatatggt ttaattagtt ttacatttgg cacttttttg atttctttta aagctatata
    18481 ttgccctcaa aatacattaa aaaacatcct tagaagtaat ttttaagttt tacttctaaa
    18541 gatgtctaac ttctatttat ctattatttt atttttaatc ttacgtcacc ttttattctt
    18601 cttattaatg ggtgattaac tgttctcatt acatggtcag taatatgata tacacctaac
    18661 tttaattttg gtgcagaacc cattactgtg ttactacagt cagtacagtt tcctattaat
    18721 ataacttctg ctccagcttt cttaaattca atacattttt gagcttgtcc tggacagtgt
    18781 cctggatttt cacattttaa tgcaccttta atttcttgag cttgtttaca tttttgaact
    18841 gatactatat cagtaactcc cattttagtt gctatatctc tcattctctc ttcattaggt
    18901 ccacatgcac agactaaaag acccattttt ctcttttcat taacaaatgg catagtaact
    18961 attataccac cactagtttt agttattgga gcatctaaag tagtagcttt accagtgaaa
    19021 ggtcctccta ggattatttc accatattca ccttttattc caccagctct ttcaattaat
    19081 tctccgacag ttgttccaat tggcacatct tcaaatacta tagactcttt tccactgttt
    19141 aattgaccaa ctacagttat atttttagat ataactggtc ttttttgctc aacagcctct
    19201 actattctag ttagtgtttc tacgtttatt actactgcat tagcctctga aggtaattga
    19261 gttggctcaa gtaattttcc tagaacgtct cttactattg ctctctcttc tcccattggg
    19321 tacatatcaa ctagttctgc aacttctatg ttgtctcctg gctttattac ttttttgaaa
    19381 gcttctattg cttttggatg cttgcttttt attgctagca taccttttcc agcattagta
    19441 acttccatag catattttat accttgataa actatttctg gtctttcttc tatttctttt
    19501 atattatgag ctaataaagg ttcacattca gctgcatttg ctaatattgt tccaccattt
    19561 aaatctatgt ttaattttac atgagtaggg aatcctgctc cacccattcc tactactcca
    19621 gcttctttaa ttaagtcaag tataccttct ccttttaatg gttcaaaagt atcttcttgt
    19681 acttcatcag cttcaattac tatcgcttgg tcatttattt cacttatttt tccactaaca
    19741 ctggcataaa tatttgcccc taatccagtt ggttctgcga ttagagttcc tttttttact
    19801 acatctccaa cacttactac tggcttatct ggaccaccaa cgtgttgttt taataaaata
    19861 gaatatagtt tgttcaacta gtacgccccc ttaagtatat taattttttt ataagctgtt
    19921 caaataatgt taatgctatt tttctattat aaggtcttaa catattgttt atttctatag
    19981 aacatatcgc ttattaacaa agcaatttct atgccaactt ttaaacaaac ttataccctt
    20041 tggaaatact gtcttacagc attcattaat tcttctaaat ttttaaatcc atcaaaaaaa
    20101 agtcaattat tagacacttt tttaatcaat ttaatctata attattgata ttgcatacat
    20161 gtataaaaag tgtcaaaaaa tagacaccgt ctttttatcg acacttttct aacatatact
    20221 atataattta tcacaacttt acttaaaata tacatttatt acttattaat tcttagtttt
    20281 ttgcactcca ttggaatcaa ctacataatt atctttatac aacaaatcag atattttgac
    20341 tagactgtat ccatcttttt ttagtcgact tattatagta tccaaatagt tatctacatc
    20401 atttatatta gcatggaata aaactattga accaggttga gattctttta ttactttctc
    20461 aattacatga tttggtccaa gctccttcca atctatagaa tctacatccc acttaattac
    20521 tttataacct aaatcactac aaatgtccat agctttattg tttacgtccc caaaaggagg
    20581 tctaaataaa ttagtctttt ttcctgttat attatatatt ttttctgatg tagtttctat
    20641 ctcttttgtt atgtcttctt ttgatatttc cttcaaattg gcatgagtgt ttgaatgatt
    20701 tccaatttca tgtccttttt catctatagc ttttacaatt tcttcattat catccaccca
    20761 actaccaact aaaaagaagg tagcttttac attatgttta tctaaaattt ttaaaatatc
    20821 atccatatta tcagttcccc atgctacatc aaaactcaag gctatttttt tctcatttgt
    20881 atcaacttta tatataggca tttttgaatt gtcgtattta gaacatatgt attttattcc
    20941 ataaacaaaa acaaatatta acactaataa taatgaaaaa aataaaacac tatatatcaa
    21001 agctttagtc cttttaactt ctcttttcat actattcccc ctttgaaata atttcttcta
    21061 tatttaaaat ttattttttt tcagctcaaa aaagtactgt aatatttaat ttataagaca
    21121 ataactaaaa aaataaaacc tatattgacc taattaaact ctctaaaata ctcatttatt
    21181 taattttttt atatttttta catttttacc tttatttttc tgtatatatt atttttattt
    21241 tggagaaatt agtattaaca tcacataaat aaaagtgttg ttagacatca taaactaatt
    21301 atttgaggag gaaatttact atgtcaaatt caaacagaac agtagttcca gaagcaaaag
    21361 ctgctttaaa ccaaatgaaa ttagaaatag ctaacgaaat aggtttatct aactatgaaa
    21421 acatagataa aggtaactta acagctagag aaaatggata tgttggtgga tatatgacta
    21481 agaaattagt tgaaatggct gaaagacaaa tggctggaaa ataaatagta aattttgaca
    21541 cctgggtatc aacagggctg ctaattagca gccctgtttc tctatattta tttataaaat
    21601 tgttttatat gaattattaa agattaataa tacaatacaa attgttcttt taattttgta
    21661 caaattagtt taatatatta tatatagaaa tagtttgacg gaggatgata tttatgtttg
    21721 aaaactcgtc tgaagaatta gcctatcaca aacttttaat tttatatata ttagaaaaaa
    21781 ttaaaatgga tttaactaat tctcaaataa ctcaagtagt attagagact gagatgatga
    21841 attatttttc attacaacag cttttatctc agcttatgga atctaagttt ttgactacat
    21901 ataaagactc tgacagagaa tattatgctc ttactcaaag aggcgtagaa agtctagaat
    21961 acttctttaa tcgaatacct actagtgtta ctgaaaaaat agacaagtat atagattcta
    22021 acaaagaaaa tctactagca gatactcaag taaagtctag ttttgtaaaa caaagtgata
    22081 atgaatttat tgtcaacctt agagtcatag aaaatcagtc taacttaata gatttaaatc
    22141 taaatgtttc atcagagaaa caagcaaaac ttatttgcaa taactggaaa aataatgcat
    22201 cttatatgta tgccgaagtt atcgatttac ttataagaga catacattaa agcctacaaa
    22261 caaattatag ttgtaggctc ttttcctacc ttgatttctt ttattaattt attgtttgca
    22321 gtttcataaa cttttactga attttcttgt gtatctgata caaatagtag cttttcatct
    22381 ttagatattt ctaagccttg aggaatccca tttatttcaa tatttccaat gtatctactc
    22441 gttgtataat ctaaaattct tacattatta taacccaaat cagcaacata aacttttttg
    22501 ccactataat taaatcttat ttctactggt aataaaaatt catataatac cttttttata
    22561 tccatgctta cttcatctat tattataagc tttccatcaa gtgttgatat atacatttct
    22621 ttcttttgtt tatcaagctc tatatgccaa gctctaaagt ccatatttat tttcttttgt
    22681 atatttttat taattgtatc tatacatact atcgagttta tacacggtac atataatttt
    22741 ttactttctc tatcaaagtc aaatccatgt ggcatattat caactccaat aattcctatt
    22801 ggatttaatg tgtttttatc tagtacatat atactattag aatcttcatt tgccacaaac
    22861 aattcattat cactaagtac aacttgacta agacttcctc ctatagagac agtatcaatt
    22921 attttatcat tacttaaatc taagacataa agtatcccat tacttgaact aggtatgtat
    22981 attaaatttt tttctttttc tatgcaaaaa tggtgtggat atatattatc ttctaatact
    23041 atttcttttt ctagttcaag tgtagaataa tcaactatgc taatactctt tgataagtag
    23101 ttagaaatat agattttcat ataacccctc ctctctacaa tacatatact acaataatat
    23161 attatttcat tagcttgtat tatgctttat agttgcatta ttacgcatat atttggtatt
    23221 attattattg ttaaaaaaag aaataatatt taatggaggt ctttttaatg aaagtaacat
    23281 ttaatccaag tggtgtatgt tgtagagaaa tgatttttga agttgatgaa aataatgtga
    23341 ttgttgatgc tgagtttata ggaggatgta atggtaattt atcaggactt agaagcttaa
    23401 taatcggcca aaatgctctt gaagttgctg ataaattaaa cggtattgac tgtggtggaa
    23461 aaggtacttc ttgcccagac caattatcta aggctatacg tcaatctata taattactta
    23521 tataaacatc agtaaaatta ttaaaaactt actttatata aaaagagttg tccatttttt
    23581 agacaactct tttttatatc tttatttgta tatttatttt ataaaattat aatttcttta
    23641 ctaaagttct cactgtacca atcatatata atgaacctgc acttattata atatcatcct
    23701 cacttgatgt ttctaatgta taatttactg catcctctat ctcatgcttt gatgttacat
    23761 catctacata ttttaatact ttttctctta atatatctga atttatggcc cttgggttat
    23821 ttggtgttgt tgttattacc ttattaaaat gtggcaacaa tatctctaaa acactatcaa
    23881 tatctttatc ttctaacata cctattaata aggttaattt tctaccttta aaattcttat
    23941 caagtgcttt tgccaaagat tttgctccat cttcattatg tgcaccatct attataaaaa
    24001 ttggattttc ttttatcttt tctattcttc ctggccattt agtatttata agtccttttc
    24061 ttatagattc ttcatttata tttgctaatt tatttatgtc ttttagatat tttattacac
    24121 taattgccaa gatagaattg tttatttgat gttcacctat caattttatt tcaaggtctc
    24181 tataagtttc tttcattaca gtacaatcgt atatttgaga atttatatct gattttttta
    24241 tgtttatatc atcaaaatca acttctatat atttagcttt tttctcttta caaactgact
    24301 ttataacatc cttcgcttca tcagtctggt catatactag tactactcca ttttccttta
    24361 ttattccagc cttttcgtac gctatttttt ctattgtatc tccaagtata cctgtatggt
    24421 ccaaacttat agatactatc acacttacaa gtgattttgt tattatattt gtagcatcat
    24481 atctgccacc taaaccaact tctaatgcca caaagtctac cttttgttct gaatagtaat
    24541 aaaatgccat tgcagtaacc acttcaaatt ctgttggata tgcatagcct tcttttacca
    24601 taatctctat tttttctttt attaactcaa ttattctagc aacatcatcc tgtggtatat
    24661 tttgtccatt tactcttata cgctcagtaa aagtttctaa atatggagat gtatataaac
    24721 caactttata tccacactct cttagtatat tagaaacaaa agaacacaca gaaccttttc
    24781 cattagttcc agctacatgt attatattca aagtttcttg tggatttcct aataattcta
    24841 ataactttcc gatattttct aatcctaatc ttataccgaa tttattagtt tgtgatatgt
    24901 actctaatgc ttcttcatat ttcattatct aactccccct gtattggcat tttctcttat
    24961 gctatctaat tatagtatat tttttacttt taatctaccg acaaagaata catataattt
    25021 aataccttct acattaaatt tagctacaaa tctttattta taagttttta tatctttcca
    25081 ctaattcagt cagtgtatat attgaaacta agtcatattt tgagatgtcc atataattaa
    25141 actttatgtc aaatctatgc tctagctttt tcaacagatt aaaacaatta tcataaacca
    25201 aacctatctc cttattaaaa aggctaccct taaagagttt ttcattatta tcttcaatat
    25261 ctaaacaatc cctaacaacg tcagcaactt tcataagaag agcattttct ttgtcataca
    25321 aatccaattt aaagtttaca attctactac actcatcaaa atcacaacta tcccaatgat
    25381 ttctagttgc taatgattca agcttatcat ttaaatcaga tattgttatg cctggttttt
    25441 ctgataatat cttagctatt ttaccagtaa gctttgctga taaataacta ttacattttg
    25501 gtggtaatct ataggaatta tttatatcac aacttatata tgaattgcta tccataacac
    25561 attgaacatc atattttttg ttgtaccaaa atgaatcatc tccatctaaa gtaaatcctc
    25621 ttacacctat aacattgtta aacatagctg gataacttaa atcaaaatca ttagcgagtg
    25681 aacatactat tatttttcct tttctaaaca attcgtaaca aacttcaaat aagcccttaa
    25741 cactctctac tcctatgact gataaactta aattaattaa tcttatgtta gtgtctaaaa
    25801 ggtatcttaa tgcttcttca agaactttta tatttgtaat accatctttt ctcaaaattt
    25861 ttattacaaa taactctaca tcttcatact ctttctttat tattgatgca caagcagttc
    25921 catgaccatc ttcatcatca aatttatctg atataaagat ataatcatgc atacattcaa
    25981 aagcaattcc tccaactaaa ttatctttta agtaatcatg ttctttgtct attcctgtat
    26041 ctaatactgc aaccttaact ttattattca tatcacatat attctccatt acaaaagttt
    26101 ttaatatatc tatgttaata gttcatctta aactttgatt taagttgcac aatttatctt
    26161 ttaaatgcta tatttcttgc taaaaacata aaataagtac accatatatt taatttatat
    26221 ttattatatc aattattatc attaaatggt taaatgttaa gataaaattt ttagatttat
    26281 atcacaattt aggattattt gtaaaaaagg agattatctt tttattagac aatccccttg
    26341 tatattttat taatatttat ctatgattaa gcatcaattt tattttatac tttttgattt
    26401 taatactata catctaaatc ttatttaggg ggaacaatta tttatatgat ataaaaatgc
    26461 taatttgaat gaacttgtct tataatcagt tttataaaat acaccattct acaaagtatg
    26521 aatcaaaagg tgaaaaaata ctaaaaataa taaatcaaca tcaattttaa ccaatatatg
    26581 aaaaacttat accaagtatg cataaaaact aatataaata ttattttaac aactaatact
    26641 tacaccttta tatattatat catatttcaa taaataaatt gcataaaagg aaatcttttc
    26701 atagaattaa accatttatt aattcattac tataggttca ataaactata agatgtcgct
    26761 ttaatattta tattatactc cattaaatat taatataatt aattaaagta tgcatagcta
    26821 aatgaaacaa atatctatag agttttataa atagtcatta ttttaaaaag gtaatcatat
    26881 tctaaaaata catataatgc atataaaaat caataatagt atattaataa tcaggctact
    26941 aattaataat catgctactg taatggaaac tctacatata catattaaac aatattaaaa
    27001 gtctataaac tgatattttg cataataaaa ctgtcttaat ataaataaca ttttatatat
    27061 taagacagtt ttaatcaata gccctgtgat gacattaaat cttttttacg atattttcaa
    27121 ttaccttttt aaaattaata cattatatca cataacaagc ttgttaatgc tacttttaaa
    27181 tctttaagtc tatacttact tataggtata aattgttcat taatagtaat catattatcc
    27241 ctaagatctt ctattcttct taaattaaca ataaaacttg tatgacatct aaaaaagcca
    27301 ttttcacaca gtaatttttc tgcttgtttc atgctcatat tagctttata atctctacct
    27361 attgtatgta caactaaatc tctctttaca gtttcaacat ataaaataga atctatcagt
    27421 attctattaa atcctttttt actatttaaa actatataac gctccttctt tctttgaagg
    27481 ttatcaatac aaagatttac acccattgca aagttactat actctatagg ctttactaaa
    27541 tatctataag cacgaacctc ataaccttgg ggggcatact ctgaaaaagc tgttgtaaat
    27601 ataatttcta ctttttcatc aaactttctt atttttttag ccacctcaat tccattgata
    27661 tctttcattt ggatatctaa aaatataata tcaatttttt ctgggtattt ggatattaaa
    27721 tcttctccac aggaaaattc cagtatttga taatttagac atctttcaga caaaagtttt
    27781 tttgtaaact cttttagtat gcttctttgt attttttcgt catcacatat aactaccctg
    27841 aacataatat cacctccaaa tctaaaatat catttagttt actttatttc aatttccaaa
    27901 ctgtactcac tagctttcaa atttaaattt ctttataaat ttaagttgtc gattaaacta
    27961 cttatagaaa ttctctttaa tatttaaact taaattacga taaattccta tacttttcta
    28021 gatatattat gtaaaaaaat atagtaaaat aaatataata tgtatttatt acc
//
LOCUS       DAMJYN010000049        27971 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.050, whole genome shotgun sequence.
ACCESSION   DAMJYN010000049 DAMJYN010000000
VERSION     DAMJYN010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 27971)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27971)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27971
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.050"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            120..1493
                     /locus_tag="PC466_002294"
     CDS             120..1493
                     /locus_tag="PC466_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2769671.1"
                     /translation="MNEILENIDEGVHFVNKDGKTIIYNNSVQKMEKMNRHDILANSF
                     FDIVNKMKINRSTLLEVLEKREVIKDNIQKYLDKNGKEITAINTTIPIDIKGEFVGAL
                     EISKNMTTIENLLNRNYKKNLVNKVSSRQKKGYEFDDILGESNLIKEAIEKSKKACKS
                     DASVFIYGETGTGKELFSQSIHYGSNRRNYPFIAQNCAALPESLFEGILFGTSKGGFT
                     GAIDRPGLFEQANKGTLLLDEINSMPIMLQAKLLRVLQEGYVRRVGGTKDIPIDVRII
                     ATTNESPKVILNEHKMRKDLYYRLNIIHIKIPPLRDRKEDILLLCKKFISKYNKKLNK
                     KVVGISDEAIKILKNYDWQGNIRELENIIYCTMSMMEDEVQIETSMINLNDYYNLKEN
                     KESNNYSLNDLEGKTLSKIISEIEEKYIYESLEKASYNITKAASILGMNRQNLQYKIK
                     KYNIKIL"
     gene            1749..2816
                     /locus_tag="PC466_002295"
     CDS             1749..2816
                     /locus_tag="PC466_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-binding protein"
                     /protein_id="HDF2769672.1"
                     /translation="MRKVRVGIWGFGAMGIGMANMILKKEGIEIVSVCSRSTSGKSMY
                     DVLGIERGERPEVIINKNYEEVFREKSVDVVLLATDSFTKKAFDKIIFLLNRKINVIS
                     TAEQMAYPQADDADLAKKMDEVAKENGVSILGTGINPGFVLDLLVLALSGTCEEVTSI
                     KAKRVNDLSPFGKSVMEEQGVGVTREEFIKGVEDKTIAGHVGFVESINMIADGLGWKL
                     DKIEQTKEPIMTTVDRKSKYGEALAGNVAGCRQCGYGYVNGDVLIEMEHPQQIIPEVE
                     GIKTGDYVSIKGIPNIDLQINPEIPGGVGTYAMIVNSIPLIINARPGLKTMLDIPVPR
                     AIMGDIRNQIEVELEEESKAN"
     gene            2913..3221
                     /locus_tag="PC466_002296"
     CDS             2913..3221
                     /locus_tag="PC466_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-ketopentanoate thiolase"
                     /protein_id="HDF2769673.1"
                     /translation="MDAKINDWVIIHNIVLTPEERAPQVPEDTKKVSLEMWVKGFIQS
                     DASIGDLVEVKTITGRLVKGNLLKVNPYYTHDYGKCIPELLQIGIQAKEILFGGVYNE
                     "
     gene            3214..4644
                     /locus_tag="PC466_002297"
     CDS             3214..4644
                     /locus_tag="PC466_002297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent lyase/thiolase"
                     /protein_id="HDF2769674.1"
                     /translation="MNNSTSIKDMSYQAVMGRNNEIMKNAIGLDYSSFEQEGIGFDYE
                     KMMSETGYTLQDIEAIQSQYAVGNTPLIELKNLTKLARKCAKEGKGAKIFVKDEAMNA
                     SGSFKARRAATAVYHAKQMGYKGVIAATSGNYGAAVASQAAMQGLKCIIVQECYDSNG
                     VGQPEIIEKARKCEAYGAEVVQLTVGPELFYTFLVLLEETGYFNASLYSPFGIAGVET
                     LGYELAIQFREKYKKDPDIVVCTNAGGGNLTGTARGLIKAGSINTKVVGASVDLKGLH
                     MASDNQFNKKSFTTGHTGFGIPYCTWPDRSDVPRSAARPLRYMDRYVLVKQGEVFYTT
                     ELLAQLEGIERGPAGNTSLAAAFSLAQELDEDKVIVVQETEYTGAGKHICPQLTFARE
                     NGIDIKFGNPREEIAGVNLILPERPELLKCVDIDMNKIRKSFIKNCISNNHIDNIDKL
                     SNRDIEFLMEEVKSSRDFVVDVLNNL"
     gene            4722..5096
                     /locus_tag="PC466_002298"
     CDS             4722..5096
                     /locus_tag="PC466_002298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine aminomutase subunit alpha"
                     /protein_id="HDF2769675.1"
                     /translation="MKKREDDFEVRRKHLQELSDDELKERFWNLATQIVEPMIELGKK
                     NTTPSIERSVLLRMGFSSLEVKPILEGVMERGLIGKGAGHVVYKLAKSKNITVREAGL
                     LLVKGEYWDEVTCLFREGVESC"
     gene            5090..7294
                     /locus_tag="PC466_002299"
     CDS             5090..7294
                     /locus_tag="PC466_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892628.1"
                     /note="Presence of a B(12) (cobalamin)-binding domain
                     implies dependence on cobalamin itself, in one of its
                     several forms, or in some unusual lineages, dependence on
                     a cobalamin-like analog; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin-dependent protein"
                     /protein_id="HDF2769676.1"
                     /translation="MLKENKKLDIDYILKDLDKYKPKRRGWVWREHLENLEMGPFKYK
                     DCTKPLKKSVGLPSSKYFNNIDPQPSPVITTEIASGRFEDDIRRMRMAAHHGADHLMV
                     IRTAGQSHFDGLIEGTPQGIGGVPITRKQVRAQRKALDFIEEEVGRPINYHSYVSGVA
                     GPEVAVMFAEEGVNGAHQDPQYNVLYRNINMVRSFVDACEAKKIMAFANIAQIDGAHN
                     ANATAREAWKVMPELMVQHALNSIFSEKIGIDKSNICLSTVPPTAPPAPCLRIDLPYA
                     VALRELFSDYKMRAQMNTKYMESSTREATVTHVLNLLTSVLTRADIQSTITPDEGRNV
                     PWHIYNIEACDTAKQALVGMDGLMDMIELKDVGELRDKARELKERAVLYMEEISEVGG
                     YFESVEQGFFVDSGNYPERNGDGISRKIKGGVGEGTVYEREEDYLAPVTAHFGYNNVA
                     QYDENAIDNPSMLIDGCTFENPDKIIYIDELDDFDNVENRLKESYEYRNGTKIKPEME
                     WCADGIVMITMMLPTDKRTAEFAALEFVKKMNLQEIEVISREVMHESEGTRIEVKGRV
                     PFDIDLNNLVIPEEPKVLTDEEIRADIEEKPMKIVSATVGEDEHSVGLREIIDIKHGG
                     IEKYGIECHYLGTSVPVEKLVDAAIELNADAILASTIISHDDIHYKNMKKLHDYCVEK
                     GIRDKVMIACGGTQVTPEIAVEQGIDAGFGRNSKGIHVATFLVEKRREMSNK"
     gene            7294..8703
                     /locus_tag="PC466_002300"
     CDS             7294..8703
                     /locus_tag="PC466_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate mutase L"
                     /protein_id="HDF2769677.1"
                     /translation="MENSKVSLKIDVLVAEIGSTTTVVNAFHDINTNNPIFLGQGQAP
                     TTVFEGGDVRNGLSGAIKDLANKLSVDDIEYNDMFATSSAAGGLKMTVHGLVYDMTVK
                     AAKEAALGAGAVIRQITSGRIKRTDLNKIKEINPNIILIAGGVDYGERDTAIYNAEMI
                     ASMNLGIPVIYAGNVENQEEIRLIFEDTNYKLYITENVYPKIDLLNIEPTRRIIQSVF
                     EEHITTAPGMKYIKEMVNENITPTPGAVMEASKLLYKNIGDLLTLDVGGATTDVHSVT
                     DGSDYINKILVNPEPTAKRSVEGDLGVYVNMKNIVEVIGKENLQSELYIDIDAVIENY
                     PPIPKSKEEILFVERLTKEAVVKAMLRHSGKIRNIYGTTGKVKIAEGKDLTEVRYIVG
                     TGGALTRLPSRIEILDNMLKYNKNNELLFPKEKTKILIDNDYIMASMGVLSKKYEEAS
                     LKLLLKSLNFEEERLCILG"
     gene            8688..9752
                     /locus_tag="PC466_002301"
     CDS             8688..9752
                     /locus_tag="PC466_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine/ornithine racemase family PLP-dependent
                     enzyme"
                     /protein_id="HDF2769678.1"
                     /translation="MYPRLEIDIEKLKHNAKLISQMCHERSIKISFVTKSFCAQKEIV
                     EEICSEGIDHIADSRIQNLKKLQDINLPKILIRIPMLSELEEVINYCDISFNSELETI
                     KKLNELCESKNIIHKIVLMFDLGDLREGYFYEEDFFNNVREIVRLKNIEIIGIATNLT
                     CYGAIIPSRENIGRLVSIAKRMEEKFGINLEIVSGGNSSSIHLLINNNMPEGITNLRI
                     GESILLGRETAYGENINGTYQDAFKLICQVVECKEKPSVPIGEIGVDAFRNKPVYEDK
                     GILKRAIIAIGKQDINIDSLIPIDTDIKILGASSDHMILDVSNTKYDYKLGDNLEFLL
                     TYGGIMSSSTSKYVSKKIIV"
     gene            9782..11203
                     /gene="nhaC"
                     /locus_tag="PC466_002302"
     CDS             9782..11203
                     /gene="nhaC"
                     /locus_tag="PC466_002302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HDF2769679.1"
                     /translation="MKERECRKASLFDAMIPITCLILFLSLGVLVYGSSPHVPLIGAA
                     AVAGLVAVYRLGFKWKELELSMFNSIKMAMQAILIIIIIGVLIGTWIVSGVVPCMIYW
                     GLKILSPNIFLVASTLVCAIVSLATGSSWSTMGTVGVALLGIGQSLGMPIGLIVGSII
                     SGAYFGDKLSPLSETTNLAPAMAGTDLFTHIKYMLYSTIPSLLICLVIYGVIGMKYSG
                     QALDIKQIELIRSTLDSTFNTLSPVLLLAPAIVIGLVVFKVPAIPGLIVGAVLGVLFA
                     VVFQGESMNTILDAAQNGYVSSTQIQEVDALLSKGGIMNMMSTVSLTICALSLGGILE
                     KTGMLEVVASSLLRLAKGVFGTVLCTMVTCTITNIIAGEQYLSIVIPGRMYNKEYKKR
                     GIHPKMLSRALEDSGTLTSPLVPWNTCGAYITATLGVSALTYGPYALLNIINPIVSLV
                     LIACKFKIARIEDEPETCLNFDV"
     gene            11632..12096
                     /locus_tag="PC466_002303"
     CDS             11632..12096
                     /locus_tag="PC466_002303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HDF2769680.1"
                     /translation="MTRISNITIAEQSEYCFLAIRKTIDFMVEFSEFSKQSFEKISKY
                     LEERGILSSGAPIVCFHNMDLAKLDVEVGFPVATYIDGKNEILQRIVPAQKIITAIDL
                     GPYELQDPTLEDLFSWANSNGYKLHGDIYYQYLNDINRPASEYLTKMMLPII"
     gene            12394..12756
                     /locus_tag="PC466_002304"
     CDS             12394..12756
                     /locus_tag="PC466_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDF2769681.1"
                     /translation="MKIYDILTRFYIQDIEKAIPFYENLLKEKCSLRFSYKEVGLELA
                     QIGNVLLLSGSDDALKPFIETKSTFMVDSVDEWRSYLLDNGAVVVRDKKKVPTGYNMT
                     LRHPDGTIIEYVQHTKQD"
     gene            13351..14211
                     /locus_tag="PC466_002305"
     CDS             13351..14211
                     /locus_tag="PC466_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2769682.1"
                     /translation="MSYKVINVITAIDYIEEHLSEKLDLDIIANAVHYSKYHLHRTFT
                     TSVGLTMHDYIKRRKLTEAAKLLVFSKKPIIEIALIAGYESQQAFTSIFKAMYKKSPN
                     KYRKEQEFYPLQLRFVLKKDNLFSKNVLELEKEIKLASMSDIPLWMNLVRLVIDGFPN
                     LQEEEYIYQLEQYILEERALILKLNNVAIANMVFNRETRSIDFFGIHPQYRNSDIAQV
                     FLKKVIEDFLIDTDISITTFREGDKADTGHRDMIKKLGFAEAELLVEFGYPTQKFILP
                     CVEERDNRQN"
     gene            14469..16583
                     /locus_tag="PC466_002306"
     CDS             14469..16583
                     /locus_tag="PC466_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF2769683.1"
                     /translation="MSENKQVVNCDIIASNSKHNMCEHDVELLTFFPDEIAHLIEINN
                     KLDNAFKKAENLVDKLDKDYMDAKMYMVKNRGEIDPHEMFQNEQGLKQIDNYGAFMVK
                     VRDKINKIKDSPYFARIDFRLKDMDDESKYYIGRFAFDYEDELIILDWRSPIASMFYD
                     YEIGKAGYDAPIGWVDGEITRKRQFKIKNGKLEYALESSINIQDDILQKELSHTSDEK
                     MKSIISTIQKEQNQIIRNDKADTLIIQGVAGSGKTSIALHRIAFLLYRFKDKISANNV
                     IILSPNKVFGDYISNVLPELGEEPLCELSFENIAEVQLDRVINFESEKDPLEINDAKW
                     SERVRFKSTLDFVKLIDDYIKQMPNKIFIPKDYTFGSFTAKSDWIQSRFEAYNRYPVK
                     KRLEKVAEDIHYKFESDNIMEEDLPKVKSILKSLNGMLTIKNTLTLYKDFFKQMNISN
                     MFVMAEKKTLEWSDVYPFIYIHAAYEGIQEDKIIRHIVIDEMQDYTPIQYAVINLLFK
                     CKKTILGDFGQLVNPNHTHTLDDMKQLYNDGELVMLNKSYRSTFEIINFAKKIQDISS
                     LEPIERHGEEPALLKCNNEQDEINKIKIEIEEFKKSDNATLGIILKTDNDAKAVYDAL
                     REEYSVHLISSESSSFTKGVSITSIKMSKGLEFDEVIVPSVNNKTYYSDYDRSLLYIA
                     CTRAMHKLKLTYVGTLTQLISM"
     gene            complement(16845..19088)
                     /locus_tag="PC466_002307"
     CDS             complement(16845..19088)
                     /locus_tag="PC466_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HDF2769684.1"
                     /translation="MSNIIIKGLTQNNLKNISFKIPKNKIVVFTGVSGSGKSSIVFDT
                     IAAESQRQMNETYSSFIRNRLPKYRKPQVELIDNLTASVIVDQTPLGGNARSTVGTIS
                     DLYSSLRLLFSRIGEPYIGTTSYFSFNDPNGMCKNCSGIGRVKVINIESIINPENSWN
                     TGCINDSLFKPNSWYWKQYAESGLFDLDKPIKDYSFEEYNLLLYGSKNKDGKQENPKI
                     EGIFNKYNQTYLNRDISNMSKHTKEKSERLITDKECPVCHGKRLNKETLNCNILGYSI
                     ADMCNMELTDLYDLLLQIKDKRTETVIKTLTDGLKRMIDIGLPYLHLNRESSSLSGGE
                     AQRLKLVRYMGSSLTGMTYIFDEPSAGMHPRDVHRMNQLLKKLRDRGNTVLVVEHDKD
                     VISIADEVIDIGPSAGTQGGHVVFQGSYDKLLLANTLTSNAMNLSLPIKTDSRHPKGT
                     LPIRDACINNLKHIDVDLPVGIMTVVTGVAGSGKSTLISRVFAQKYEKDVIKIDQSPV
                     TATNRSMPATFLGFFDEIRKVFAKENNVEEGLFSFNSKGACPVCDGKGVLVTELVFMD
                     PIINTCEACKGTRYSEEVLSKLYKGKCIVDVLSMTVDESLEFFTEKKLCKILQTMKDV
                     GLPYMTLGQPLSTLSGGERQRIKLAKNLNKKGTIYILDEPTTGLHGSDIEKLMLIFEH
                     IVDKGNTVIIIEHNLDVLKQADWVIDIGPDGGKNGGQVVFEGTPLEMFERGCTITSDF
                     LRKSINI"
     gene            19420..20136
                     /locus_tag="PC466_002308"
     CDS             19420..20136
                     /locus_tag="PC466_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769685.1"
                     /translation="MILIVILSIFIIASINIIILGKENIRDIVIPLTLFIVSDFLFLC
                     GNIICRGGVMLLFIGLFAIPLMLIAFIWICVHMIKLYYKKDLNKRKMIGCIFSIFISI
                     GTIFIPSPSESFRFKLYEKDYSVVAKAILKVYDEKKLSSESVFYIQSDKNELEKIFSK
                     EVIKKMKKLNRNLDVVKISGNRNLVYFFFGAELQSIDGIVIFKDLKHVKPKLDFINRS
                     IQAPRLEYITNNVYYFKGEL"
     gene            20164..21102
                     /gene="blaCDD"
                     /locus_tag="PC466_002309"
     CDS             20164..21102
                     /gene="blaCDD"
                     /locus_tag="PC466_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDD family class D beta-lactamase"
                     /protein_id="HDF2769686.1"
                     /translation="MKRKNNFIWIVILLVVVAMGVYYVGRKHNNTKQKHDKNHINSEL
                     NKSKVENNDKNKKEKINMVDYSDCFEGISGGAIFYNTKNKEYNIYNKELIETRRSPCS
                     TFKIVSTLIGLEKGVINSKESVMGYDGTEYPNKNWNKNLSLEEAFKESCVWYYKKLID
                     KVDAKSVQNILDDLKYGNCDISEWEGDLKNGKGHLNGFWLESSLQISPKEQVQTMAKI
                     FEGDTNFKKEHINILRDIMKIDVNDKNINVYGKTGTGFDEKNKRVDAWFVGMLEREGD
                     TYYFAIKSDDSNKEITGPKVKEIAINIIKKYYSVRE"
     gene            21446..22129
                     /locus_tag="PC466_002310"
     CDS             21446..22129
                     /locus_tag="PC466_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2769687.1"
                     /translation="MEILKCENLTKIYGSNQTRVTALNNVNLSVQKGDFVSIVGASGS
                     GKSTLLHLLGGVDRPTSGKIYVEDTEISSLKEEALAVFRRRKVGLIYQFYNLIPTLDV
                     RKNILLPMLLDKRKVDEDRFSEIVSILGLSDRLNHLPSQLSGGQQQRVSIARSLIYRP
                     AILLADEPTGNLDRKNSEEIVDLLNLSNKRFNQTILLITHDEKIALEANRIVTMEDGV
                     IVSEKVVKK"
     gene            22126..24786
                     /locus_tag="PC466_002311"
     CDS             22126..24786
                     /locus_tag="PC466_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2769688.1"
                     /translation="MNILQEYTLDFVRRNKRSSIAIMLAILLTTTMMSSLCGLLYTMW
                     TDFIRLSIEKEGNWHGELFDYTYGSDLPLIENFSSVDDVMVKGQWYVGKINDEKRDYI
                     IYRNATSEYWNSMPEKDTIIEGRRPNNANEIALSKQYFENNPSVKIGDKITLPIGDRI
                     LNGKPLEPIAQKSKGESFKKISETTLTIVGKVDVSTSSVIPAYTALGYLDRTSIKPND
                     SITVYLRFKNIRDTYKELPKLAKSLGWKTNEYGKYNLKYNSNYLLKMLVFSPEQKASM
                     SSISKFSTPIMYLTIAIFTVAVFVMVIYNAFSLSANARLTQLGILSSVGASPKQIKMS
                     VVFEGFLLTIIPLPIGLFLGWLLCNRLIVYINSVNYHTDVPEVVFTYGIPAFLPAVLL
                     TIVTVWISALIPARKVSKISPIEAIRQGDSVKIKKSHKYSLGKIFGIEGELASNALRA
                     RKKSYRTATISLTLSFLLLTCFLHIIANQEGAKAVYGSDNYKDQRDIAVYLENSEPVE
                     SAFIEKLDNTEGVKSSLYYQKMSASTWLTEKDASKELAKNGGFKSIVSSKKYSPIERD
                     GKFRIISNIIGLDDKSFTEYCRQISVDPKLFYDTKNPTSIVYNKEEDINRSTRRNKVY
                     IDYLNLSIGDNIKLNEKVYDEDKGDYTYNMKVGAITSTLPKTVDTSSKYTLMQIVPMS
                     MVQEISKNYDEVSRLRSNRLIGVFKVNNREDIPRVREKLESIYNKDYGSGDYSIEDVL
                     ESEKQKASGIKTMNLIVGFITGLLAMIGLSNVLATVSGNTRSRRQEFAMLRSVGLSPE
                     GIKKMLVLEGLFLGITPLLLSIPVQIGIVYAFLRINEIYFIEYLPFAPISTIIGFTIL
                     ILFIVIASYMTGYKQLKNENIVESIKNETI"
     gene            complement(24967..26148)
                     /locus_tag="PC466_002312"
     CDS             complement(24967..26148)
                     /locus_tag="PC466_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2769689.1"
                     /translation="MKTPRNINSTVVFIIFCLIITFLLSVILTTITSFNEYNVLSKAL
                     GASYEYNPKSTESILKSLKNSSDKDFKTGNEILSKHGYSKSTFWSKNFFYFLVISFGI
                     ISTMATVVYIIKHRTNKQKLSRINNLTQYLEEVNLGKESVLLRCEDEFSHLEDEIYKT
                     VGELRCSKEFALKERQTLSDNLADIAHQLKTPITSMSLMAQLLSENCPDEEIDYINRL
                     TNQISRLERLVSSLLTLSKLDASTLIFESKLIDVHSLLTYAIEPIEGSLREKHQTFTI
                     EASPSVEFEIDINWTLEALLNILKNCSEHIEDGGYIVAYYSQNPLYVEIIIEDNGKGF
                     AQEELPYIFNRFYRGKNASKDSIGIGLALSKSIIERQNGTLHAENCHNGGARFIIKFY
                     T"
     gene            complement(26148..26810)
                     /locus_tag="PC466_002313"
     CDS             complement(26148..26810)
                     /locus_tag="PC466_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2769690.1"
                     /translation="MAKILLLEDDDTITFGIKTSLEKKNHTVCCYNTIAEAKKNFDKT
                     IDLILLDLNLPDGIGYEFCQYVKSIEDTPVIFLTVRDDEKDIIRGLDMGADDYVVKPF
                     LLSVLQSRINAVLRRTHSNTNNTITCGNISLNKVEVKAYLDNVEVLLTAGEYKLLLSL
                     MENKNRAMTRTKLLEMLWDVDGNFVNDNTLTVTIKRLREKLKNPPCIKTLRGIGYRME
                     DS"
     gene            complement(26955..27497)
                     /locus_tag="PC466_002314"
                     /pseudo
     CDS             complement(26955..27497)
                     /locus_tag="PC466_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417472.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
     gene            complement(27615..27971)
                     /locus_tag="PC466_002315"
                     /pseudo
     CDS             complement(27615..27971)
                     /locus_tag="PC466_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
BASE COUNT        10662 a         3374 c         4830 g         9105 t
ORIGIN      
        1 aaaatatcat aaatatatga taagataaat acaatagcaa tattttatta attttttggg
       61 tttttatata tttaggtact ggggtgatat agttgaacca agagatattt tttaaaataa
      121 tgaatgaaat attggaaaat attgatgaag gggtacattt tgttaataaa gacgggaaaa
      181 ctataatcta caataattct gtacaaaaaa tggaaaaaat gaacagacac gatattttag
      241 ccaattcatt ttttgatata gtcaacaaaa tgaaaataaa caggagtaca ctattagaag
      301 ttttggaaaa aagggaagtt atcaaagaca atattcaaaa atatctggac aaaaatggaa
      361 aagagataac agcaattaat actacaatac caattgatat taaaggcgag tttgtagggg
      421 cacttgaaat atcaaagaat atgacaacga tagaaaattt actaaacaga aattataaaa
      481 aaaatttagt caataaagtt agtagtagac aaaaaaaggg ttatgaattt gatgatattt
      541 taggggaaag taatttgatt aaagaagcaa tagaaaaatc taagaaagct tgcaagtctg
      601 atgcttcagt atttatatac ggtgaaactg gaacgggtaa agagttattt agccagtcca
      661 ttcattatgg aagtaatagg agaaactatc catttatagc acaaaattgt gcggctttgc
      721 cggaatcact attcgaaggt atcctttttg gaactagcaa gggaggattt acaggagcaa
      781 tagataggcc aggcttattt gaacaagcta acaaagggac attgttattg gatgagataa
      841 attccatgcc tattatgtta caggctaaac tattaagggt tttacaagaa ggttatgtaa
      901 gaagggttgg aggaactaag gatataccta tagatgtaag aattattgca acgacaaatg
      961 aaagtccaaa ggtaatttta aacgagcata aaatgcgaaa agatttatat tataggctta
     1021 acataattca tataaaaatt cctcctctta gagatagaaa agaggacata cttctattgt
     1081 gcaaaaaatt tatttcaaag tataataaaa agttaaataa aaaagtggta ggaatttcag
     1141 atgaagctat taaaatttta aaaaattacg attggcaagg taacataaga gagctagaaa
     1201 acataattta ttgtactatg agtatgatgg aagatgaggt acaaatagaa acaagtatga
     1261 ttaatctaaa cgactattac aatcttaaag agaataaaga gagtaacaat tattctttaa
     1321 acgatttgga gggcaaaaca cttagtaaga ttatcagtga gatagaagaa aagtatatat
     1381 atgaatcatt agaaaaggca tcgtacaata taactaaagc tgcatcaatt ttaggtatga
     1441 ataggcaaaa tttacagtat aaaataaaaa aatataatat caaaatatta taaataagca
     1501 agataaaaaa acaaaataga agtaaaataa aaaagcaaaa tataggagca aaattattat
     1561 aaaagagcaa aatattttgc tctttttttt atttctcata agaaatatta ttttttattt
     1621 atgaaaatac ataataaaat aattatagtt tcaacgttcc aataaatatt tactttaatt
     1681 ttaaagttgg cacgatttat gctttaacta attattgaga atatataaat ttttaggagg
     1741 gtgtatatat gagaaaagta agagtaggaa tatggggatt tggagctatg ggaataggta
     1801 tggctaatat gattctaaag aaagaaggta tagaaatagt atctgtttgt agtagaagta
     1861 cttcagggaa aagtatgtat gatgttttag gaattgaaag aggagaaaga ccagaagtta
     1921 ttatcaataa aaattatgaa gaagttttta gagaaaaaag tgtagatgtt gttttgttag
     1981 caactgattc atttactaaa aaggcttttg ataaaataat tttcttatta aatagaaaaa
     2041 taaatgttat atcaacagca gaacaaatgg catatccaca agctgatgat gcagatttag
     2101 ctaaaaaaat ggatgaagtt gcaaaggaaa atggagtaag tatacttgga acaggaataa
     2161 atccaggatt tgtattagat ttactagtat tggcactttc aggtacttgt gaagaagtta
     2221 ctagtataaa agctaagaga gtaaatgatt tatctccatt tggaaaatct gttatggagg
     2281 aacaaggtgt tggagtaaca agggaagaat ttataaaagg tgtagaagat aagactatag
     2341 caggtcatgt aggttttgta gaatcaataa atatgatagc tgatggatta ggttggaaat
     2401 tagataagat agaacaaaca aaagagccaa taatgactac agtagataga aaatctaaat
     2461 acggagaggc attggctgga aatgttgctg gttgtagaca atgtggatat ggatatgtaa
     2521 atggagacgt tttaattgaa atggagcatc cacaacagat aataccagaa gtagaaggta
     2581 ttaaaacagg agactatgta tcaataaaag gtataccaaa cattgattta caaataaatc
     2641 ctgaaatacc tggaggagta ggtacttatg caatgatagt aaactctatt ccattaataa
     2701 taaatgctag accaggtctt aaaactatgt tggatatacc agtgcctaga gcaataatgg
     2761 gagacataag aaatcagata gaagttgaat tggaagaaga atcaaaggct aattagtaag
     2821 ataacagtta gctaattggt aaaataatgt ttaatttaaa ataacagtaa attaattagt
     2881 aaggaatagt caattaataa ggggatgaaa aaatggatgc taaaattaat gattgggtta
     2941 ttatacacaa tatagtattg actccagaag aaagagctcc acaagttcca gaggatacta
     3001 agaaagtatc cttagaaatg tgggttaaag gttttataca aagtgatgct tctataggcg
     3061 acttagtaga agttaaaaca attacaggta gacttgtaaa aggtaattta cttaaagtaa
     3121 atccatatta tactcatgat tatggtaaat gtataccaga gttactccaa ataggaatcc
     3181 aagctaaaga aatattattt ggaggtgtat ataatgaata attcaacatc aataaaagat
     3241 atgagttatc aagctgttat gggaagaaat aacgaaataa tgaaaaatgc aatcggattg
     3301 gattattctt cttttgaaca agagggaata gggtttgatt atgagaaaat gatgagtgaa
     3361 acaggatata cattacaaga tattgaagca attcaatcac agtatgctgt tggaaatact
     3421 cctctaatag agcttaaaaa tttgactaaa ttagctagaa aatgtgctaa agaaggtaaa
     3481 ggagctaaaa tatttgtaaa agatgaagca atgaatgcat ctggtagttt taaagcaaga
     3541 agagcagcta ctgcagtata tcatgccaaa caaatgggat ataaaggtgt aatagcagct
     3601 accagtggta actatggtgc agctgtagca tcacaagcgg caatgcaggg attaaaatgt
     3661 ataatagttc aagaatgtta tgattctaat ggtgtaggtc aacctgaaat tatagaaaaa
     3721 gcacgaaaat gtgaggcata tggagcagaa gttgttcagt taactgttgg accagagtta
     3781 ttttatacgt tcttagtttt attagaagaa acaggctatt ttaacgcatc attatattca
     3841 ccatttggaa ttgcaggtgt agaaacttta ggttatgagt tagctatcca atttagagaa
     3901 aagtataaaa aagaccctga tatagttgtt tgtacaaatg caggtggtgg taatcttact
     3961 ggaactgcaa gaggattgat aaaagctggt tccattaata ctaaagtagt aggagcaagt
     4021 gtagatttaa aaggattaca catggctagt gataatcaat ttaataaaaa atcatttaca
     4081 acaggacata caggttttgg gataccatac tgtacatggc ctgataggtc agatgtacct
     4141 aggtctgcag ctagaccact tagatatatg gatagatatg tattagtaaa acaaggagaa
     4201 gttttttata caactgaatt attggcacag ctagaaggta tagaaagagg tccagcagga
     4261 aatacatctt tagcagcagc attctcttta gctcaagagt tagatgagga taaagttata
     4321 gtggtacaag aaacagaata tacaggcgca ggtaaacata tatgtccaca gcttactttt
     4381 gcaagagaaa atggaataga tataaaattt ggaaatccaa gagaagaaat tgcaggagta
     4441 aacttaatat taccagaaag accagaatta ttgaaatgtg ttgatattga tatgaataaa
     4501 ataagaaagt catttataaa aaattgcata tctaataatc acattgataa tattgataag
     4561 ctaagtaatc gagatataga atttttaatg gaagaagtaa aaagttcaag agattttgtt
     4621 gttgatgtat taaataattt atagtaatta ttgttttttt atttaatata aaataaaaat
     4681 tcggaaaatt ctattaaatc aatgcgaatg gaggaatgtt catgaaaaaa agagaggatg
     4741 attttgaagt tagaagaaaa catcttcaag aactgagtga tgatgagtta aaagaaaggt
     4801 tttggaattt agctacccag atagtagaac caatgataga acttggtaaa aagaatacaa
     4861 caccatcaat agaaaggtct gtcttgttga gaatgggatt ttcttctctt gaagtaaaac
     4921 ctattttaga aggggttatg gaaagaggtc ttataggtaa aggagcaggg catgtagttt
     4981 ataaattggc taaatctaaa aatataacgg ttagagaagc aggtttgtta ttagttaagg
     5041 gtgaatattg ggatgaagtt acatgtttat ttagagaagg ggtagaatca tgttaaagga
     5101 aaataaaaaa ttggatatag actatatatt aaaagatttg gataaatata aaccaaaacg
     5161 aagaggttgg gtttggagag aacacttgga aaatcttgaa atgggacctt ttaaatataa
     5221 agactgtaca aaacctttaa agaagagtgt agggctacca tcatctaagt atttcaataa
     5281 tatagaccct caaccaagtc cagttattac tactgaaata gcttctggta gatttgagga
     5341 tgatataaga agaatgagaa tggcagctca tcatggagct gaccatctaa tggttatcag
     5401 aactgctgga caatcacatt ttgatgggct tatagaagga actccacaag gtataggtgg
     5461 agttccaata acaagaaaac aagtaagagc tcaaaggaag gctcttgatt ttatagaaga
     5521 agaagttggt agacctatta attaccattc atatgtaagt ggtgttgctg gtcctgaagt
     5581 agcagtaatg tttgctgagg aaggagtcaa tggagcacat caagacccac aatataatgt
     5641 tctgtatagg aatataaaca tggtaaggtc ttttgtagat gcttgtgagg caaagaaaat
     5701 aatggctttt gccaatatag ctcaaattga tggagcacat aatgctaatg ctactgctag
     5761 agaagcatgg aaggtaatgc ctgaacttat ggttcaacac gctttaaact ctatattctc
     5821 agaaaaaata ggtatagata aaagtaatat atgcttatca acagttccac caacagcacc
     5881 tccagcacca tgtttaagaa tagacttacc ttacgctgtt gcacttagag aattatttag
     5941 tgattataag atgagagctc aaatgaatac taaatatatg gaatcatcaa ctagagaagc
     6001 aacagttact catgtattaa acttattaac atcagtatta actagagctg acatacaatc
     6061 aactataaca cctgatgaag gtagaaatgt accttggcat atatacaata tagaagcatg
     6121 tgatacagca aagcaagctt tagttggtat ggatgggctt atggatatga tagaacttaa
     6181 agatgtcggt gaattaagag acaaagcaag agaacttaaa gaaagagctg tattatatat
     6241 ggaagaaata tctgaagttg gtggatattt tgaatctgtg gaacaaggat tttttgttga
     6301 ttctggaaat tatccagaaa gaaatggtga tggaatatct agaaaaataa aaggtggagt
     6361 tggtgaaggt actgtttatg aaagagaaga agattattta gcacctgtaa ctgctcactt
     6421 tggatacaat aatgtagctc aatatgatga aaatgctata gataatccat caatgttaat
     6481 agatggatgt acatttgaaa atccagacaa aataatatat attgatgagc ttgacgattt
     6541 tgataatgta gaaaatagac taaaagaatc atatgagtac agaaatggaa ctaaaattaa
     6601 gcctgaaatg gaatggtgtg cagatggaat tgtaatgata acaatgatgc ttcctactga
     6661 taaaagaaca gcagagtttg cagctttgga atttgtcaaa aaaatgaact tacaagaaat
     6721 tgaggtcata agtagagaag ttatgcatga atctgaaggg actagaatag aagtgaaagg
     6781 aagagttccg tttgatatag atttaaacaa tttagtaata ccagaagaac ctaaggtact
     6841 aactgatgaa gaaataagag cagatataga agaaaaacct atgaaaatag tttcagctac
     6901 ggttggagaa gatgaacatt cagttggttt aagagaaata atagatataa aacatggagg
     6961 tattgaaaaa tatggcatag aatgccacta tctagggact tctgtacctg tagaaaaatt
     7021 ggtagatgca gcgattgaac tgaatgcaga tgcaatactt gcatctacaa taataagtca
     7081 tgatgatatt cactataaaa acatgaaaaa attacacgat tattgtgtag aaaaaggtat
     7141 aagagataaa gtaatgattg cgtgtggagg aacacaagta acacctgaaa tagctgttga
     7201 acaaggcatc gatgctggat ttggaagaaa cagcaaaggc atacatgtag ccactttctt
     7261 agttgaaaaa agaagagaaa tgagtaataa ataatggaaa atagcaaagt ttctttaaaa
     7321 atagatgtgt tggtagctga aattggaagt actactacag tggtaaacgc tttccacgat
     7381 attaatacta acaatcctat atttttgggt caaggtcaag ctccaacaac agtgtttgaa
     7441 ggtggcgatg taagaaatgg cttatcaggt gctattaaag atttagctaa taaattatct
     7501 gtagatgata tagagtataa tgatatgttt gcaacttcta gtgcagctgg tggattaaaa
     7561 atgactgttc atggattagt ctatgatatg acagtaaaag cagctaaaga agcagcttta
     7621 ggggctggag ctgttattcg tcaaataaca tcaggtagaa ttaaaagaac tgatttaaat
     7681 aaaataaaag aaataaaccc aaacataatt ttaatagctg gtggagtcga ttatggagaa
     7741 agagatacag ctatttataa tgcagaaatg atagcttcta tgaatctagg cataccagtt
     7801 atatatgctg gtaatgttga aaatcaagag gaaataaggt taatatttga agatactaat
     7861 tataagcttt atataactga aaatgtatac cctaaaatag atttattgaa tatagaacct
     7921 acaagaagaa tcattcaaag tgtatttgaa gaacacataa ctacagcacc aggaatgaaa
     7981 tacattaaag aaatggttaa tgaaaatatt actccaaccc caggagctgt aatggaagct
     8041 tctaaacttt tatataaaaa tattggagat ttattaactt tggatgtagg tggagcaact
     8101 actgatgtac attctgttac agatggaagt gactatatta ataaaatttt ggttaatcct
     8161 gaacctactg caaagagaag tgttgagggg gatttaggtg tatatgtaaa tatgaagaat
     8221 atagtagaag ttataggtaa agaaaactta caaagtgaac tatatataga tattgatgca
     8281 gtaatagaga attatcctcc aataccaaaa tcaaaagaag aaatattatt tgttgagagg
     8341 ttgacaaaag aagctgttgt taaagctatg ctaagacatt caggaaaaat aagaaatatc
     8401 tatggaacaa ctggaaaagt caaaattgca gaagggaaag atttaacaga agtaagatat
     8461 atagttggta cagggggagc acttactagg ctccctagta gaattgaaat attagataat
     8521 atgctcaaat acaataaaaa taatgaatta ctatttccaa aggaaaaaac aaagatatta
     8581 atagataatg actatattat ggcatctatg ggtgttttat ctaaaaaata tgaagaagca
     8641 tctcttaagc tcctgttaaa aagtttgaat tttgaggagg aaagattatg tatcctaggt
     8701 tagaaataga tatagaaaag ttaaagcata atgcaaaatt aatttcgcag atgtgtcatg
     8761 aaagaagtat taagatatct tttgttacta aatcattttg tgcacaaaaa gaaatagtag
     8821 aagaaatatg tagtgaagga atagaccata tagcagattc aagaatacaa aacttaaaaa
     8881 aattacaaga tataaatcta cctaagatat tgattagaat cccaatgtta agtgaattag
     8941 aagaagttat caattattgc gatattagtt ttaactcaga attagaaaca ataaagaaat
     9001 taaatgaatt atgtgaaagt aaaaatatta ttcataagat agttcttatg tttgacttag
     9061 gcgatttacg agaaggatac ttttatgaag aagacttttt taataatgta agagagatag
     9121 taagattaaa aaatattgaa ataattggta tagctacaaa cttaacctgt tatggagcta
     9181 ttataccatc tagggaaaat ataggcagac tggtaagtat agcaaaaaga atggaagaaa
     9241 aatttggaat aaatctagaa atagtatctg gaggtaattc aagttctatt catctgttga
     9301 taaataataa tatgccagaa ggtattacta atttgagaat aggcgagtcc attctacttg
     9361 gtagagaaac ggcatacggt gaaaatataa atggaacata tcaagatgca tttaaattaa
     9421 tatgccaagt agttgaatgt aaagaaaaac catcagttcc tattggagaa ataggagttg
     9481 atgcctttag aaataaacct gtttatgaag ataagggaat cttaaaaagg gcaatcatag
     9541 ctataggtaa acaagatata aatattgact ctttaattcc aatagacact gatataaaaa
     9601 tattaggggc aagttcagac cacatgatac tagatgtaag taacacaaaa tatgattata
     9661 aattaggtga caatttagaa tttttattaa cttatggggg tatcatgtca tctagtacaa
     9721 gcaaatatgt ttcaaaaaaa attatagtgt agtgtttaaa taattaggag gaaactattt
     9781 tatgaaagag cgagaatgta gaaaagcaag tctgtttgat gcaatgatac caattacttg
     9841 tttgatatta tttttaagtc taggagtatt agtgtatggt tcatcacctc atgtaccact
     9901 aataggagca gcagcagtag caggacttgt ggctgtatat agacttggat ttaaatggaa
     9961 agagttagaa ttaagtatgt ttaatagtat aaagatggca atgcaagcaa tcttaatcat
    10021 aattataata ggcgtactta taggaacttg gatagtaagt ggagtagttc catgtatgat
    10081 ttactgggga ctaaaaattt tatcaccaaa tattttttta gtagcatcaa cattagtctg
    10141 tgcaatagta tctcttgcga caggttcatc ttggagcaca atgggtacag taggagtagc
    10201 tcttttagga attggtcaaa gtttaggtat gccaattgga ttaatcgtag gttctataat
    10261 atctggagct tactttggag ataaactatc acctttatct gaaacgacta acttagctcc
    10321 agcaatggca ggaacagatt tgtttacaca tataaaatat atgttatatt cgactatacc
    10381 atcattatta atttgtttag taatttatgg tgtaattgga atgaagtatt caggtcaagc
    10441 actagatata aaacaaatag aattaattag gtctacatta gattctacat ttaatacttt
    10501 atcaccagta ttattattag ctccagcaat agtaattgga ttagttgtat ttaaagttcc
    10561 tgctatacca gggcttatag taggtgctgt attgggagta ttgtttgcag tagtttttca
    10621 aggagaatct atgaatacga tattagatgc agcacaaaat ggatatgttt cgtcaacaca
    10681 aatacaggag gtagatgctt tattatctaa aggtgggatt atgaatatga tgtccactgt
    10741 atccttaaca atatgcgctt tatctcttgg aggtatttta gaaaaaacag gtatgcttga
    10801 agtagtagca tcttctttac taagattagc aaagggtgta tttggaacag tattatgtac
    10861 tatggtaact tgtacaatta ccaatataat agcaggtgaa caatatctat ctatagttat
    10921 accaggaaga atgtataata aggaatataa aaagagaggt atacatccta agatgttgtc
    10981 gagagcttta gaagatagcg gaactttaac ttctccatta gtaccatgga atacatgcgg
    11041 ggcgtatata acagcaacat taggtgtatc tgcactaaca tatggtccat acgctttatt
    11101 aaatattata aatccaatag tatctttagt attaattgca tgtaagttta aaatagcaag
    11161 aatagaagat gaacctgaaa cttgtttaaa ttttgatgtt tgataataga taacttatgt
    11221 aagaacgtag gaactagggg gggagcctgt ggggaattag taagacatat tttagtgtgc
    11281 gaaattctat aaatcagtaa tcttgtgact ttagccatgg gaggttcaga ttagtaaatt
    11341 tatagtttta tattagtcta tactttgatc ttttaattgt ttgtataaat tttttataga
    11401 aaaagatttc ttttagactt gcctaaaaat taggcaagtc ttttaagtat gttctgatta
    11461 taagagcact gtgtgacaag aatgatgaga ttatttttgc tatactttcg atataagaaa
    11521 tggaaggagg ttatgtttta tatttatatg aaataattag ttacacagtg aattttcgta
    11581 taatttggta taaaaagatt agaaatgaaa ataaagtaat ggaggaataa aatgactaga
    11641 atatccaata taacaatagc tgaacaatct gagtactgtt ttttggcaat acgaaaaaca
    11701 attgacttta tggtagagtt ttcagagttt tcaaaacaaa gttttgaaaa aatttctaaa
    11761 tatctggagg agagaggaat tttatcttca ggagcaccga ttgtatgttt tcataacatg
    11821 gatttagcaa aattggatgt tgaagtaggg tttcctgtag ccacttatat agatgggaaa
    11881 aatgagattc tacaaaggat tgttcctgca cagaaaataa taactgcaat tgatttagga
    11941 ccttatgaat tacaagaccc tactttagaa gacttatttt catgggcaaa tagcaatgga
    12001 tataaacttc atggcgatat atattaccag tatttaaatg atatcaatcg tccagctagt
    12061 gaatatctta cgaaaatgat gttacccatt atatagaaag ttaaagatta tcgtttgtta
    12121 gttgataatt agaagaacat ttaatgctac tgcataaatt ttatcctaaa taatatcaag
    12181 gtgatttaat ttatgtattc taatgtaact gtagataatc aatttataac taacttagtg
    12241 taatttagat ttaatttatt attctaatgt aaccccaata tattgttaag gtctacttaa
    12301 gatgctcaaa aggctatgct taatttattg ttatataatt tgtagagtgg tataatttag
    12361 aagtgatact atatagatat atagggggaa aatatgaaaa tatatgatat attaacacgt
    12421 ttttatattc aagatataga aaaagccata cctttttatg agaatctttt aaaagaaaaa
    12481 tgttctttgc gtttttctta taaagaagtt gggttggaat tagcgcaaat aggaaatgtt
    12541 ttactattat ctggttctga tgatgctctt aaaccattta tagaaacaaa atctactttt
    12601 atggttgatt ctgttgatga atggagaagt tatctattgg ataatggagc agttgtagta
    12661 agagataaga aaaaagttcc tacaggatat aatatgacat tgagacatcc agatggtaca
    12721 attatagaat atgttcaaca tacaaagcag gattagttaa aaatagattt tactactgag
    12781 caactaatta gaatctattc ttagacgtac aatttattat ttttggtatt aatagattat
    12841 aagtcaaatt ataatatttc aaaatagaat agaaatttat ttacataaaa gagagtgttt
    12901 aaaaatgaac tttttagttc acgaagcact cctttttgta tgaaatcaaa tacatcaata
    12961 tataaaacaa actgatgaag agcttaaatt aaaataaaaa gattcataac aggaccccat
    13021 taaactttaa gatagggtaa gtttgtaatc atattaaata attgtaaaaa gctgttttta
    13081 gtcgtataat ataaatattt atcatttaat taaggaatct aaaaggaatc taataagaag
    13141 aaaataataa ataacttttt agatttacta aatgaaaaat tattgaaaat taaaggatta
    13201 gagtctttaa tcagaaagta aaaagtaata tattaaattt atgaattgaa aacttaaaca
    13261 acaaatttgt ttataaaata gcaagattca ttaaatataa ctaagtaata attgatataa
    13321 tgttgcatgg ataaaaggag ggaagctgca atgtcttaca aagtaattaa tgtcataact
    13381 gctattgact atatagagga gcatttatca gaaaagctgg atttagatat aattgctaat
    13441 gctgttcatt actcaaaata tcacctgcat agaactttca caacttctgt tggtctaaca
    13501 atgcatgatt acataaagcg gagaaagttg acagaagcag caaaattatt ggtattttca
    13561 aagaaaccaa ttattgaaat tgcattgata gctggatatg aaagtcaaca ggcattcact
    13621 tctatattta aagctatgta taaaaaatct ccaaataaat ataggaaaga acaagaattt
    13681 tatcctttgc agctaagatt tgttttgaaa aaagataacc tattttcaaa gaatgtacta
    13741 gagttggaaa aagaaattaa acttgcaagt atgtctgaca taccattatg gatgaattta
    13801 gtgagattag tcatagatgg atttccaaat ttgcaagagg aagaatatat atatcaatta
    13861 gaacagtata ttttagaaga aagagcttta atattaaaac ttaataatgt cgctattgca
    13921 aatatggtgt ttaatagaga aactagaagt attgattttt ttggaataca tccacagtat
    13981 cgtaattcag acattgcaca agtgtttttg aagaaagtta ttgaagattt cttgatagat
    14041 acagatatct caattactac ctttcgagag ggtgacaaag ctgatacagg acatagagat
    14101 atgataaaga agttggggtt tgcagaagca gagttgcttg tggaatttgg atatcctact
    14161 caaaaattta ttcttccttg tgtagaagaa agagataata gacaaaatta attgtagatt
    14221 aaatgcaaag tttaccacat attttttgtt tgaattattt tatatataag agtatttctg
    14281 cttttaatgt attttgcttg taagtgtact tatggtaata aatatagaaa gatttagttt
    14341 tttaaaaaaa gaactttaaa gctaaaaagc taacatttaa gttaaatagc aagaatgatt
    14401 aaaaactcca aaacacaatt aagtataatg attcagtgta agtacttaat taacaaagga
    14461 ggatttaaat gtctgaaaat aaacaagtag taaattgcga tattattgca tccaattcta
    14521 aacataatat gtgtgaacat gatgtagagt tattaacttt ttttccagat gagattgcac
    14581 atctaataga gataaataac aagctagaca atgcttttaa gaaagctgaa aatcttgttg
    14641 acaagcttga taaggattat atggacgcta aaatgtatat ggtaaaaaat cgtggtgaaa
    14701 tagacccaca tgaaatgttt caaaatgaac aaggactaaa acaaatagat aactatgggg
    14761 cttttatggt aaaagttcga gataagatta ataaaatcaa agattctcca tactttgcta
    14821 gaatagattt taggctgaaa gatatggatg atgaatctaa gtattatatt ggtagatttg
    14881 catttgatta tgaagatgag cttataatac ttgactggcg ttctccaatt gccagtatgt
    14941 tttatgatta tgaaatcgga aaagctggat atgatgctcc aataggatgg gtggatggag
    15001 aaataacaag aaaacgacaa tttaaaatta aaaatggaaa attggaatat gcactagaaa
    15061 gttccattaa tatacaagat gatattcttc aaaaagaact tagtcacact tcagatgaaa
    15121 aaatgaagtc aatcatttca acaatacaaa aggaacaaaa tcaaattatt agaaatgata
    15181 aagctgatac actgattatt caaggggtag ctggttctgg gaaaacatct atagcattac
    15241 acagaattgc ttttcttctt tatcgattta aagataaaat atcagcaaat aatgtaatta
    15301 tcctatcacc taataaagtc tttggagact atatttccaa tgtccttcct gagcttggag
    15361 aagaaccatt atgtgaatta agttttgaaa atatagcaga ggtacaatta gatagagtta
    15421 ttaattttga aagtgagaaa gacccattag aaataaatga tgctaaatgg tctgaaagag
    15481 tgcgttttaa atctacactt gattttgtaa aacttattga tgattatata aaacaaatgc
    15541 caaataagat ttttattcca aaagactaca cttttggaag ttttacagct aaaagtgact
    15601 ggatacagag tagatttgag gcatataaca gatatccagt taagaagaga ttagaaaagg
    15661 tagctgaaga cattcattat aaatttgaat cagataatat tatggaagaa gatttaccaa
    15721 aggtaaaaag tatacttaaa agtttgaatg gaatgttgac aataaaaaat actcttacac
    15781 tatataagga tttctttaaa caaatgaata tatcaaacat gtttgtgatg gcagaaaaga
    15841 aaacacttga atggtcagat gtatacccat ttatatatat tcatgctgca tatgaaggta
    15901 tacaagaaga taagattata aggcatattg ttattgatga aatgcaggac tatacaccta
    15961 ttcaatatgc tgtaataaac ttacttttta agtgtaaaaa gactattctt ggagattttg
    16021 gacaattggt taatcctaat catactcata cattagatga tatgaaacag ctatataatg
    16081 atggggaact agttatgttg aacaagagtt accgttctac ttttgagatt attaatttcg
    16141 ccaaaaagat tcaagatata tcttcattag agcctattga acgacatggt gaagaaccgg
    16201 ctttattaaa atgtaataac gagcaagatg aaataaataa gataaaaata gaaattgaag
    16261 aatttaaaaa gagtgataat gcgactcttg gtattatatt aaagacagat aatgacgcta
    16321 aagctgtata tgatgcgtta agagaagaat atagtgttca cttaatatct tctgaaagtt
    16381 ctagctttac aaaaggagta tccataactt ctattaaaat gtcaaaaggt ttagagtttg
    16441 atgaagttat tgtaccttca gtaaataata aaacatatta tagtgattat gaccgcagtt
    16501 tgttatatat tgcttgtaca cgagctatgc acaaacttaa gttaacatat gttggtacat
    16561 taactcaact tataagcatg tagattatat cttatatgca tttattatcg taaatataaa
    16621 ttgggacaaa gattcatcaa taaatcaaca aaaaataata cttataaatt tataaaaaat
    16681 gaaagctata aattacattt gaaattttat aaaattttgt gatttatagc ttttataata
    16741 ttaatttctt ttaaaataaa gttaaacttt aaatttatga aataaaacaa agtagtaata
    16801 tatatgtaat agttcttaat tttttaatat tagtattata ttatctatat atttattgat
    16861 tttctaagga aatctgatgt tatagtgcaa cctctttcaa acatttctag tggtgtacct
    16921 tcaaatacga cctgaccacc gtttttgcca ccatcaggac caatatcaat tacccagtct
    16981 gcttgtttca atacatccaa attatgttca attataatta cagtattacc tttatcaact
    17041 atatgctcaa aaatcaacat aagcttttca atatcagaac catgaagccc tgtagttggc
    17101 tcatctaaaa tatatatagt accttttttg ttgaggtttt tagctaactt aattcgttga
    17161 cgttctcctc cagatagtgt gctaagtggt tgacctaagg tcatataagg taaaccaaca
    17221 tctttcattg tttgtaagat tttacatagc ttcttttctg taaaaaattc aagagattca
    17281 tctactgtca tagatagtac atcaactata catttacctt tatataattt tgacaaaact
    17341 tcttcactat atctagtacc tttgcaagct tcacatgtat taataatagg gtccatgaat
    17401 acaagctctg taacaagtac tcctttacca tcacaaacag gacaagctcc ctttgaatta
    17461 aagctgaata aaccttcttc aacattattt tctttagcaa atacttttct tatctcatca
    17521 aagaaaccaa gaaatgtagc aggcatagaa cgatttgtag ctgtaactgg gctttggtcg
    17581 attttaataa catctttttc gtatttttgt gcaaaaacac gagagattaa agtactcttg
    17641 ccagaacctg ctactccagt aacgacagtc ataattccaa ctggtaaatc tacatcaata
    17701 tgttttagat tatttatgca agcatctcta attggaaggg taccttttgg atgacgagag
    17761 tcagttttta taggtaatga tagattcatt gcatttgaag taagagtgtt tgctaaaagt
    17821 aatttatcat aagagccttg gaatacaaca tgtccaccct gagtaccagc acttgggcca
    17881 atatctataa cttcatctgc tatggagata acatctttat catgctctac tacaaggaca
    17941 gtatttcctc tatctctaag tttttttaat agctgattca tacgatgtac atctcgtgga
    18001 tgcataccag cactaggttc atcgaaaata taagtcatac ctgtgagact gctccccata
    18061 tagcgtacaa gttttaatct ttgagcttct cctccagata gagatgatga ttctctattt
    18121 agatgtaggt aagggagacc aatatcaatc attcttttta aaccatcagt aagagtcttt
    18181 attacagttt cagttctttt atcttttatt tgtaacaata aatcataaag gtcagtaagt
    18241 tccatattgc acatatctgc aatcgaatat cctaaaatat tacagttaag agtttcttta
    18301 tttaatcttt ttccatgaca tacaggacat tccttatctg ttataagtct ttctgatttt
    18361 tcttttgtgt gtttgctcat attgctaata tctcgattta gatatgtttg attgtatttg
    18421 ttaaaaatac cctctatttt tggattttct tgttttccat ctttattttt tgaaccataa
    18481 agcaataaat tatattcttc aaaagaataa tcttttatag gtttatctaa atcaaaaagt
    18541 ccagactctg catactgctt ccagtaccat gaattaggtt taaataaaga gtcatttata
    18601 catcctgtat tccatgaatt ttcaggattt ataatagatt caatattgat tactttaact
    18661 ctaccaatcc cagaacaatt tttacacata ccatttgggt cattaaaaga aaaatatgaa
    18721 gttgttccta tgtagggttc tccaattcta gaaaataata atcttaatga tgaatacaaa
    18781 tcacttatag tgccaactgt agaacgtgca ttgccaccaa gaggagtttg gtctacgatt
    18841 acagaagcag ttaaattatc aatcagctcc acctgaggtt ttctatattt aggtagccta
    18901 tttctgataa atgaagaata tgtttcattc atctgccttt gtgattctgc tgcaattgta
    18961 tcaaatacga tactggattt tccagaacca gaaactccag taaaaacaac aattttattt
    19021 ttaggaattt taaatgatat attttttagg ttattttgtg taagtccttt tattataata
    19081 tttgacatga atgttaaatc ctttctgagt acattttagt aaagcaatta tattatgtaa
    19141 ccatattata ataaaattaa aatctacttt cttgatatat tctgctatgt tatagaaggt
    19201 atttctaaat ttaaccaatc ccatacaatc tgaataaatg atagttgata atagataaaa
    19261 aagtatataa tagatactcg taatttgata agtacaaaga taattataca attaaaacga
    19321 cttgacattt aaaacttact attgtaatat ttaaatatta caatagtaag ttttaaatag
    19381 agaataaata attacctcac aaactgaaag gaggacataa tgatactaat agttatattg
    19441 agtatattca tcatagcctc aatcaacata attatattag gtaaagaaaa tataagagat
    19501 atagttatcc ctttaactct atttattgta agtgattttt tatttttgtg tggaaatata
    19561 atatgtaggg gaggagtaat gctactattt ataggtttat ttgcaatacc attgatgcta
    19621 attgcattta tatggatttg tgtacatatg attaagcttt actataaaaa agatttaaat
    19681 aaaagaaaaa tgattggatg tatatttagt atctttataa gtataggtac tatatttatt
    19741 cctagtccaa gtgaaagttt tagatttaaa ctttatgaaa aagattatag tgtagtagct
    19801 aaagctattt tgaaagttta tgatgaaaaa aagttaagct ctgaatctgt cttttatatt
    19861 caatctgata aaaatgaatt ggagaagata ttttctaaag aagtaataaa aaaaatgaaa
    19921 aaactaaaca gaaatttaga tgtagttaaa atttctggga atagaaattt agtctatttt
    19981 ttctttggag ctgaattaca atctattgat ggtattgtga tttttaaaga tttaaaacat
    20041 gttaaaccaa agttagattt tataaataga agtattcaag ctcctagatt ggagtatatt
    20101 acaaataatg tatattattt taaaggtgaa ctataaactt atgtagagga gatggtataa
    20161 agtatgaaaa gaaaaaataa ttttatttgg atagttattc ttctagttgt tgtagctatg
    20221 ggagtatatt atgtaggaag aaagcataac aacacaaaac aaaaacatga taagaatcat
    20281 ataaactctg aattaaataa atccaaagtt gaaaacaatg ataaaaacaa aaaagaaaaa
    20341 attaatatgg ttgactatag tgactgtttt gaaggtatta gtggaggagc tattttttat
    20401 aatactaaaa ataaagaata taatatatat aacaaagaat taattgaaac aagaaggtca
    20461 ccatgttcta cttttaaaat agtttcaact ttaattggtt tagaaaaagg ggtaataaac
    20521 tcaaaagaat cagttatggg atatgatggt acagagtatc caaataaaaa ttggaataaa
    20581 aatcttagtt tagaagaggc atttaaggag tcttgtgttt ggtactacaa aaaattgata
    20641 gataaagttg atgctaaatc tgtccaaaac attttagatg atttaaagta tgggaattgc
    20701 gatattagcg aatgggaagg agatttaaaa aatggaaagg gacatttaaa tggattttgg
    20761 ttagaatctt cattacaaat atctccaaaa gaacaagtgc aaacaatggc aaaaatattt
    20821 gagggagata caaactttaa aaaagagcat attaatattt taagagatat tatgaaaata
    20881 gatgtaaatg ataaaaacat aaatgtatat ggaaaaactg gaacaggatt tgatgaaaaa
    20941 aataaacgtg tggatgcatg gtttgttggt atgctagagc gtgaaggtga cacctattat
    21001 tttgctatta aatcagatga ttccaataaa gaaattacag ggccaaaggt aaaggaaatt
    21061 gcaattaata taattaagaa atattatagt gtaagggaat aaacttaatt ttatttgtaa
    21121 atattattta cctatagtct gtaatattta ttaaataatt ttactaaatt gagtctatat
    21181 agagcaaaac tcctttagta cataaaatac ttgctattga ttattaaatt gaatacctat
    21241 agatttaaag ttaatacctt ttaaagacta tgtaatatat taaaagtata aataaaatat
    21301 attgcatagt ttttgtttta tattataatt ttaaataatg tgcaaaaact aaacaatatt
    21361 tttaatagta atttatattt gtattcatgt cactataatg tcattttagg ttgctaaaat
    21421 ttaaccataa aggagatgat tgtatatgga aatattaaaa tgtgaaaatc tcacaaaaat
    21481 atatggttca aatcaaacca gagtgacagc ccttaataat gtaaatttat cagttcaaaa
    21541 aggtgatttt gtatccattg taggagcatc tggttctggc aaatctacat tgttacatct
    21601 gcttggggga gtagatagac ctacatctgg aaagatttat gttgaagata cagaaatatc
    21661 aagtttaaag gaagaagctc ttgcagtttt tagacgtaga aaagtaggtc ttatttatca
    21721 attttataat cttataccta cccttgatgt tagaaaaaat atattattac ccatgttact
    21781 tgataaaaga aaggtggatg aggatagatt ctctgagatt gtatctatat tgggattatc
    21841 tgatagatta aaccatcttc caagtcaact ttcaggtgga caacaacaaa gggtatctat
    21901 agctagaagt ttaatctata gaccagctat tttattagca gatgagccaa ctggtaatct
    21961 tgatagaaaa aattcagaag aaattgtaga cttgttaaac ttatcaaata aacgatttaa
    22021 tcagacaata cttcttatta ctcatgatga gaaaatagca ctagaggcaa atcgtattgt
    22081 aactatggaa gatggagtga ttgtctctga aaaggtggtg aagaaatgaa tattcttcaa
    22141 gaatacacct tagactttgt acgacgcaat aaacgtagta gtatagctat aatgttagct
    22201 atattactta ctacaaccat gatgtcttct ttgtgtggac tgttgtatac catgtggaca
    22261 gattttataa gactttcaat tgagaaagaa ggtaactggc atggtgaatt gtttgactat
    22321 acttatggaa gtgacttacc attaattgaa aatttttctt cagttgatga tgtaatggta
    22381 aaaggacaat ggtatgtagg caaaattaat gatgagaaaa gagattatat aatttataga
    22441 aatgctacat cagagtattg gaattctatg ccagaaaagg atactataat agagggtcgt
    22501 cgaccaaata atgctaatga aattgcatta tcaaaacaat attttgagaa taatccaagt
    22561 gtaaaaattg gggataaaat tactcttcca ataggagata gaatcctaaa tggaaagcct
    22621 cttgaaccca tagctcaaaa atcgaaaggg gaaagtttta aaaaaatttc agagactaca
    22681 ttgacaatag taggaaaggt agatgtttcc acttcatcag taatacctgc atatacagct
    22741 cttggatatc ttgatagaac aagtataaaa cctaatgata gtataactgt gtacttgcga
    22801 tttaaaaata taagagacac atacaaggaa cttccaaaac ttgctaaatc attggggtgg
    22861 aagactaatg aatatggaaa atacaatctt aaatataata gtaattatct tttaaaaatg
    22921 ttagtctttt ccccagaaca gaaagcatct atgagcagta tatcaaaatt ttcaactcct
    22981 attatgtatc ttacaatagc aatttttaca gtagctgtgt ttgtaatggt gatttacaac
    23041 gcgttttcac tatctgcaaa tgctagactt actcaattag ggatattatc tagtgttggt
    23101 gcatcaccaa aacagattaa aatgtctgta gtgtttgaag gttttttgct tacaattata
    23161 ccattgccaa taggtttatt tttaggatgg ttattgtgta ataggcttat agtttatatt
    23221 aattcagtta attatcatac tgatgttcca gaagtggtat ttacttatgg tattcctgct
    23281 tttctgccag cagttttact tacaatagta acagtctgga tttctgcact tataccagca
    23341 cgaaaagtat caaagatatc tcctatagaa gcaatacgac aaggagatag tgttaaaatc
    23401 aaaaagtcgc ataaatattc attaggaaag atatttggaa tagaaggaga acttgcatca
    23461 aacgcactac gtgctcgtaa aaaatcttat cgtactgcaa caatatcttt aacattatct
    23521 tttttattac ttacatgttt tttgcatata attgcaaatc aagaaggagc aaaagctgtt
    23581 tatggaagtg ataattataa ggaccaaaga gatatagcag tttatttgga aaatagtgaa
    23641 cctgtagagt ctgctttcat tgaaaaatta gataatacag aaggtgtaaa aagttcacta
    23701 tattatcaaa aaatgtctgc ttccacttgg ctgactgaaa aagatgcatc aaaagaactt
    23761 gcgaaaaatg gaggatttaa aagtatagtt tcatctaaaa aatactctcc tatagaacgt
    23821 gatggcaagt ttcgtataat ttcaaatata attgggcttg atgataagag ttttacagaa
    23881 tattgtaggc aaatttctgt agacccaaag ttattttatg atacaaaaaa tccaacctca
    23941 attgtatata ataaggagga agatattaat cgtagtacac gtagaaataa agtatatata
    24001 gattatttaa atctttcaat aggagataac attaaattaa atgaaaaagt atatgacgaa
    24061 gataaagggg attatactta caacatgaaa gtgggagcta ttacaagcac acttcctaaa
    24121 acagtagata ctagttcaaa atatacatta atgcaaatag tgccaatgtc tatggtgcag
    24181 gaaatatcta aaaattatga tgaagtaagt aggttacgtt caaataggct gataggagta
    24241 tttaaagtaa ataatcgtga ggacattcct agagtaagag aaaaattaga gtccatttat
    24301 aataaagact atggttcagg agattatagt attgaggatg ttttagaaag tgaaaaacaa
    24361 aaggctagtg gaataaagac catgaattta atagtaggct ttattacagg tttattggct
    24421 atgattggat tatcaaatgt acttgctaca gtgtcaggaa atactagaag tagacgacaa
    24481 gagtttgcta tgttgcgttc tgttggatta tctccagaag gcataaaaaa gatgcttgtt
    24541 ttggaaggtt tgttcttagg aattacacca ttactactta gtattcctgt gcaaatagga
    24601 atagtgtatg cttttctacg tataaatgaa atatatttta tagagtattt accatttgca
    24661 cctatatcta caataatagg ttttactata ttgatacttt ttattgtaat agcatcatat
    24721 atgacaggat acaagcagtt gaagaatgaa aatatagtag aatctataaa aaatgaaaca
    24781 atataaacaa aagctatttg aacttattta aaggtttcga tttaagacta cttacaagta
    24841 tagggatagt taatttgttt gtttaataaa accttaaatg taaatagaag tatattacta
    24901 aaacaataga taacatagaa tatagatata gctggattat aggtatttta cctataatcc
    24961 agcattttat gtgtaaaatt taattatgaa tcttgcacca ccattatggc aattttctgc
    25021 atgtagagta ccattttgac gttctataat agactttgat agagcaagcc ctataccaat
    25081 actgtcctta ctagcatttt taccacgata aaatctatta aaaatatatg gaagttcttc
    25141 ctgagcaaac cctttaccat tatcttctat gataatctca acatatagag gattttgact
    25201 ataataagca actatatatc caccatcttc tatatgctca ctacaatttt taagaatatt
    25261 taaaagagct tctaaagtcc aattaatatc gatttcaaat tctaccgaag gagaagcctc
    25321 gatagtaaat gtctgatgtt tttctcttaa agaaccttct ataggctcaa ttgcataagt
    25381 aagaagagaa tgtacatcta taagtttgct ttcaaatatt aaagtacttg catccaattt
    25441 tgataatgta agtaaagatg aaactagtct ctcaagtctt gagatttgat ttgtaagtct
    25501 gttaatataa tctatttctt catctggaca attttctgaa agtaattgtg ccataagtga
    25561 catagaagta attggagtct taagttgatg agcaatatct gcaagattat ctgaaagagt
    25621 ttgtctttct tttaaagcaa attcttttga acaacgaagt tccccaactg ttttatatat
    25681 ctcatcttca aggtgagaaa attcatcttc acatcgtaaa agtacagact cttttcctaa
    25741 attcacttct tctaagtatt gagtaagatt gtttattcta ctcagttttt gcttatttgt
    25801 tctatgtttg attatatata caactgtagc cattgttgaa attataccaa acgatatcac
    25861 tagaaaataa aaaaagtttt tactccaaaa tgtactttta gaatatccat gttttgataa
    25921 aatttcattt cctgttttaa aatccttatc actagaattt ttcagtgatt ttagtatact
    25981 ttctgtagac ttaggattgt actcatatga tgcaccaaga gccttagaca gtacattgta
    26041 ttcattaaaa gaagttatag ttgttagaat tacacttaat aaaaaagtta taattaagca
    26101 gaatattata aaaacaactg tactgttgat atttcttgga gttttcacta gctgtcctcc
    26161 attctatatc ctatgcctct taatgttttt atacaaggtg gattttttaa tttttctcta
    26221 agacgcttta ttgtaacagt aagagtgtta tcatttacga aattaccatc tacatcccag
    26281 agcatttcta gtaactttgt acgggtcata gctctatttt tattttccat aagacttaga
    26341 agaagtttat attctcctgc tgtcaaaagt acttcaacat tatctaaata tgctttgact
    26401 tcaactttat tcaagcttat atttccacat gtaatagtat tgttagtatt tgaatgagtt
    26461 cttctaagaa ctgcattaat tctggattga agtactgaga gcagaaatgg tttaaccaca
    26521 tagtcatctg cacccatatc taatccacgt ataatgtctt tttcatcatc acggactgtc
    26581 aaaaatatca ctggagtatc ttctatactt ttaacatatt ggcaaaactc gtatccaata
    26641 ccatcaggta gatttaaatc aagcagaatt aaatcaatag ttttatcaaa atttttttta
    26701 gcttcagcaa tcgtattata acaacataca gtgtgatttt tcttttcaag ggaagttttt
    26761 attccaaatg taattgtatc atcatcttct aaaagaagta ttttagccat ttacttttag
    26821 tcctttcagt aatttagtta tttcattaac taagttatta gttttatgtt taatattttt
    26881 tatgttagag atagaagtta gagatagaaa aaattatcat ttaagtatat aaactttaat
    26941 ttataaactt aggtttatgc tttaattgaa tctattaaaa gagcaagagt tgtttcaata
    27001 aatttttcct catctatatt aaagttgttc aggtatgact ttcctgttac agatagtaaa
    27061 ttaaaaaatc ctgtaagtgt aaatattgat gaatacatga gagtaggtat ttcaatatca
    27121 tgcctaatac ttctatcatt ttttccaatt tcaaacattc cttgtatttc atcaaacata
    27181 aatttattaa aagaaaaaaa cttttcttta aacagcatat cagtatccga tttttcagag
    27241 tttacaatac caatcattcc cataaggcat aatagagaag gttctacaga gtaaaattta
    27301 tgaaaagcaa agtatgaaag ttttattttt tcaaaccctg ttttgccttt tgcactttct
    27361 attttaacat tatcccaaag tcttttatat cctcttaaga caacagcaaa gaataaatct
    27421 tctttacatg aaaagtactt gtatatggtg cgtttagtat attcaacttc ttttgccaac
    27481 tcattcatag ttgtattctg aacctcccat gactaaagtc acagggttcc tgcttcatag
    27541 aattttgcat actaaaatat gtcttactaa ttctccacag gccatccccg tagttcctac
    27601 ggttcttaca taagttattt attttgaatc gttattagtc ttaatccttc ttttaatata
    27661 tttatacttg catttatatc tctatcgtga gtttcattac aactaggaca aatccattct
    27721 cttatattta agttcttaac ttcctcgttt ttatacccac atttattgca tatttgtgaa
    27781 cttgcaaaga atttacctac tttatacaat ttgtctacca taccaattag ccttgtattc
    27841 taattgacga ataaattctg accatgatac atcagaaatt aagcgagata gtttatgatt
    27901 tttaatcata ttctttactt gtaaatcttc tatgcaaata atatcattct cttttattaa
    27961 tttagtagat a
//
LOCUS       DAMJYN010000050        27795 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.051, whole genome shotgun sequence.
ACCESSION   DAMJYN010000050 DAMJYN010000000
VERSION     DAMJYN010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 27795)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27795)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27795
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.051"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            46..120
                     /locus_tag="PC466_002316"
     tRNA            46..120
                     /locus_tag="PC466_002316"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:78..80,aa:Thr,seq:tgt)
     gene            complement(280..957)
                     /gene="srtB"
                     /locus_tag="PC466_002317"
     CDS             complement(280..957)
                     /gene="srtB"
                     /locus_tag="PC466_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtB"
                     /protein_id="HDF2769691.1"
                     /translation="MKKLYRIVINIILVLVILYSGFNIYSKLTKYNHDTKTSSELQKK
                     EYKKEDLSKINSDFKFWLSVENTNINYPVVQSKDNSYYLDKDFYKKDSISGTLFMDYR
                     NKSIDDKNIIIYGHNMKNKTMFNNLNKFKDADFFKNNNKIKITLNGKEFLYDVFSAYI
                     VESDYDYLKTNFNNESDYQNYINDITSKSLYKSPIKVNSNDKIVTLSTCTYEFDDARM
                     VIHGRLI"
     gene            1089..1423
                     /gene="rnpB"
                     /locus_tag="PC466_002318"
     ncRNA           1089..1423
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="PC466_002318"
                     /product="RNase P RNA component class A"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00010"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00010"
     gene            1701..4244
                     /locus_tag="PC466_002319"
     CDS             1701..4244
                     /locus_tag="PC466_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPOR domain-containing protein"
                     /protein_id="HDF2769692.1"
                     /translation="MKVLSENNIIRNTVLNVTASFLKQESKINEKLDGVLEKKFEKVE
                     FNEAKYAELLKFNILFYKTLARNTEPLIGKWIVDKYIPEIDELEKDLELTTAKCRKYV
                     NKAMKEGLDSLKANDLNSFLAYDKMELSERRRRLEKDYKVLNLYKDLLNISLRKISLE
                     KKECGDLFLKNQADAKRELKREIIFCVNKILASNKDVVPNNVEENNEQDKVEIKATEI
                     EDLQLGKDNSENDMLLNEIKNSKVKHESKSNDIESKFIDKLNSLNNESISQTIHNEYK
                     KLCGLEELHSVEGYGFGKEIIKDFACATVVLEFLKRRNRDLIEGAMRLTIIGEFGPEN
                     FKEFVDYVIKNKTEISEDTWNKAQNLIKDNYSELENHEIASKRTRRNKDIDIEEYIYM
                     IKNADKDICFRSSISIEDDAEEGAKEEVDSNNQDIGDVVEDKDTTDKEYDSNKEDIIE
                     PENKKSKKKAKLFGFIKKDNEEVEQEEENLNDISPDIILDKPVENHQAKSEEIEQNEL
                     KEIKQEEPSQHIEEERSVKIEKPINNNLDEKVSSNNESKLEKESKNLEDKKAKEIKEE
                     KLENEKSVVIPIKKKENSNKKSKNSSKDKYRENKKEMKNYVSDKEDSLDDEEVVSKKS
                     RLKETIIAVVIVVIVGVGYFITVGNNKKNDKENIPKSSTQQQANNKLTEEEKKAQAEK
                     EKKEAEEKAKAEKEAQEKAQAEKKAKEMEAYKDGKGVYYTVYAGSLKVEKTAKETAKE
                     YEAKGISSTIIQENGYYKIKIGDYSQYGEAQEKCNELAKKSIDTYIAMYDKYYDYKLE
                     ELKESAPSLSAEELKQKYEDLRSELKNKSGYREYVKHLDKLYEEIVEGA"
     gene            4366..6357
                     /locus_tag="PC466_002320"
     CDS             4366..6357
                     /locus_tag="PC466_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769693.1"
                     /translation="MLKLGEKIIYELSDGFELSGISRYSKEYKKLHITNLGNIIISKS
                     DEVNEDTGVKYIYSFSDNKEKLEAVLEDSQIIVYGNNLPFYIKSENSSKNVTANLTMK
                     ITLDEYDLICKSQREFIFYLKDNMTILSLDDNKFYMGGINKDNEKFIFISGKNRFEIN
                     FDDIERYILEDKRVSLKGYFHMEREGIIVRSVSIFNNNIDSVVPSDLNERVKDNQKIG
                     NLPKDCDIVFCKISGNIDGFDYKNTNMLLVKYQDQLIFINKKSKKTIVKSAKDNCSKL
                     NLGEDIILYDNKNVFNLHINDKNREIMQIDDLKDIENEIVGYTLKHAPFFIQEDFDSL
                     TILKSFQKEIISIKNSDIKDIVINKELENENSNFVETEIKFNNQKVLLNLSKNMVQKL
                     MQDVFIYAKQPLLKENSIEVIYKNWSKAMNDMIIFNFFGNIYYMKSEFDKILEKELND
                     EIRIEVINSLYKQIQEQRNNLDLLSAYMPRILENQEIDLFEKYNTKLDVQVFKQIKNL
                     LSDLSYNISSYLNEVEKSLDNIIFVISGEDKKKYNYRMLKESESASLDVFLKQAISRL
                     NHLVENMYPYYVDETSREMFKLFELLWKNYRNIDDDSIKEILFERITNTYVFKQLTLN
                     NSTKERRKDIIEKIYNSVDYGTNKLDENMFFTGGIKYVK"
     gene            6347..6667
                     /locus_tag="PC466_002321"
     CDS             6347..6667
                     /locus_tag="PC466_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769694.1"
                     /translation="MSSKYNVWTFNYEFLGLDSGDEKNNEVYYEIDLDEILNENYIDE
                     DIDSGLDSDGNSILGELISEMDIDEDVSVDMTYQELEVDLEDLDSYLDEDIDSDIKGI
                     LDEI"
     gene            6865..7734
                     /gene="galU"
                     /locus_tag="PC466_002322"
     CDS             6865..7734
                     /gene="galU"
                     /locus_tag="PC466_002322"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HDF2769695.1"
                     /translation="MTVKKAIIPAAGLGTRFLPATKSQPKEMLPIVDKPTLQYIIEEA
                     IESGIEEILIITGRNKKSIEDHFDKSVELELELEQKGKTEMLEMVRDISNMVNIHYIR
                     QKEPKGLGHAIYCAKSFIGDEPFAVLLGDDIVDSDVPCLKQLIDTYNEYKTTVLGVQK
                     IAKEDTNKYGILDVKHIEDRVYKVKDMVEKPAIEEAPSDIAILGRYIITPAIFSILEK
                     QTPGKGGEIQLTDALQTLGKQEAIYAYNFEGRRYDVGDKIGFLEATIDFALKRENLKD
                     DLMDYMRKKVSEK"
     gene            7759..8772
                     /gene="galE"
                     /locus_tag="PC466_002323"
     CDS             7759..8772
                     /gene="galE"
                     /locus_tag="PC466_002323"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HDF2769696.1"
                     /translation="MAVLVAGGAGYIGSHTAIELLESGYEVVIVDNLSNSNSIVVDRI
                     KELSKKPVKFYNIDIRNKDEMHVVFKENNIESIIHFAALKAVGESVEKPIEYYSNNLI
                     STLNLFELMREYGVKKFVFSSSATVYGDPHTCPILEDFPLSVTNPYGRTKLMIEQMLV
                     DISKADKSLDIALLRYFNPVGAHKSGRIGEEPNGVPSNLMPYITKIAVGKLKELSVYG
                     NDYPTHDGTGVRDYIHVLDLAAGHVKALQKLEENPGLVVYNLGTGKGYSVLDLVKAFS
                     KASGKEIPYKIVGRRAGDVAMCYADSSKAEKELGWKAKYELEEMCEDSWRWQSMNPNG
                     YEE"
     gene            8884..10818
                     /locus_tag="PC466_002324"
     CDS             8884..10818
                     /locus_tag="PC466_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp22"
                     /protein_id="HDF2769697.1"
                     /translation="MKKSLKKYLVLALTLVLVFACGVPESSAASKHVIIVNSRKNTLG
                     YFVNNKLVKEFRVATGKKGSETPTGKTKVVNKIKNRPYYKGNIPGGSPRNPLGDRWMG
                     LALKGTYGDTYGIHGNNNESSIGKHISGGCIRMHNKDVRWLFDQVPVGSDVIIDYSND
                     SYVKIAAKYKINLNQTGWKTENGKKYYVKSDGTYQKNSWLKVNGKMYYFDASGVMQTG
                     WKAINNKKYYLGTDGARVSGWKVIDGKTYYFNSDGVMQTGWQEKNGKKYYLGSDGLSV
                     TGWQEIDGNKYYFDKTGIMQTGWQQIDGKSYYLDKDGKMLTGSQKIDGKDYTFNEDGT
                     INPTWDTIIGANRFDTAKKISSVGNWNADSSDTVILVNGNAIADGITATPLASSYDST
                     ILLTNTANLPTETVEEMKLLAPKTVILIGGENAISSKLEQEIKTTFNTETKRIAGQDR
                     YQTATRIAEELGNREEIKTAYMVSGNGEADALSVASKAGEEKQPIILVNKDGITEESY
                     KWLTERKLENAYFIGGPSAINDSVIAKMNDITTEDISGNRIYGDSRVDTNAKVIEKFY
                     GDTDLQAVLVSKSDALVDALSAGPLAVKLHSPIVLMDNSGLSLEQQRVFANKKVETPY
                     QIGGGVSYIVMDKLMDILAK"
     gene            10973..11836
                     /locus_tag="PC466_002325"
     CDS             10973..11836
                     /locus_tag="PC466_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3800 domain-containing protein"
                     /protein_id="HDF2769698.1"
                     /translation="MLSSYVKRVSKIIKKKYIMFIDESGRADINHEDPFTLTGVIFEY
                     KYAVSQGDYVCSLRKEMDAFKEYCFGTSNIGIHLTDISRKSRAFEKFDDSQIKLFYDE
                     LPLFLSRLECTIISVTVDKARLKKYYAPSKEPYVVAFIHVLQNFYSFVNNETVESARI
                     VIESRDDVSNLKVQKAFFDVFNNGTIYLDIDEELRDKVKGFIIAKKEDADYREGLEIA
                     DILCNPLSRARRGLIEANPKCMQYGEKNKIFKSVRNKIYTPTSVNDIRNWGFKEVPIV
                     EPVGPWLEKMR"
     gene            complement(12044..12925)
                     /locus_tag="PC466_002326"
     CDS             complement(12044..12925)
                     /locus_tag="PC466_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDF2769699.1"
                     /translation="MNLYHLRYFVTLAHLEHYTKAAENLSITQPSLSHAISLLENELG
                     VALFEKEGRNIVLTKYGKIFLKDVEKSLEILDSSVKSLKITGTGEGQIDLAFLRTLGT
                     DFIPDIVHKFLKSNPAKSIDFKFHTGVTTDIIQGLKERKYDIAFCSKLEKEKGIEFIP
                     VAKQDLVLIVPYSHPLAAKDTIDLKETIPYPQIVFNQRSGLRYIIDDMFKKINQQPNI
                     VYEVEEDQVIAGLVAKNFGIAVVPNMNMLSFTKVKVIQIIHPSWERNFYLAFIKDRYL
                     PPAIKNFKNFVIKNAQL"
     gene            13338..14186
                     /locus_tag="PC466_002327"
     CDS             13338..14186
                     /locus_tag="PC466_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HDF2769700.1"
                     /translation="MNNQKNLNIPITISSYTLGTEVSFRDRVRIAKEAGFDGIGLRAE
                     NYIDAKNAGVTDEEMIAILNEYDMKVTEVEYITQWGTEEDRTEAQREKEQNVYHMAHL
                     FNVKHINCGLLEMIPEEQIITALGELCDRAGELIIGLEFMPYSGVPDLATAWRVVKGC
                     NRENAMLILDTWHWARAKQTAEDLAPVPADKIVSIQVCDVLETPYEKLRDESLHDRLA
                     PGEGYGNTEEFVKIIKEHNISPRVIGAEVISDSLISKGLSTAAETVFNATKKVLDKAW
                     SEVSPK"
     gene            14265..16187
                     /locus_tag="PC466_002328"
     CDS             14265..16187
                     /locus_tag="PC466_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HDF2769701.1"
                     /translation="MKISSMFTPIRIGSMTVPNRFVVPPMGNNFANTDGTLSETSKAY
                     YLERALGGFGLITIESSVVDKKAKGGPRKPCLYDDSTIDSFKNVIDACHDAGSKVSIQ
                     LQHAGSEGNEKVAGHPLKAASAIPASNGRNTPLAITTEEIYELIESYGDAALRAQKAG
                     ADAVEVHCAHGYLVSSFISQRTNKRVDEFGGCFENRMRLPRLIIENIRKKVGNSLAIL
                     CRINSTDDVPGGIDIHDSSVIAAYLEGCGIDGLHVSRSIHIHDEYMWAPTTLHAGFSA
                     ELVTEIKKAVSIPVITVGRYTEPQFAELMVRQGRCDLVAFGRQSLADPEMPNKAKNGK
                     LDEMIPCIACLQGCVPNMFQGKPIACLANPILGHEAELKPAEISKEVLVVGGGVGGML
                     AAWVCAKRGHNVTLVEKSEVLGGQMRLAAYPPGKGDITNLVRSYISKCNQYGVKICTN
                     TEATVELIKEKSPDVVIIATGATPLVLPIPGINDSGLIHAVDLLDGKKSCGKKVLVVG
                     GGMVGCEVAAFLGEQEHEVTVIELREEVGADVISEHRKFLMNDFENYNIHTITGAKVS
                     KFYDDGVDYLLTDGTEHDLKGFDSVVLAMGSRNYDPLSEVIKEVVKETYIVGDAVKAR
                     RALDATKEAFEVALNI"
     gene            16269..17132
                     /gene="aroE"
                     /locus_tag="PC466_002329"
     CDS             16269..17132
                     /gene="aroE"
                     /locus_tag="PC466_002329"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HDF2769702.1"
                     /translation="MEISGRTGLFALIGTPVGHSKSPVMYNYSFKKLDLDYRYLAFDI
                     TVDKVKEALLAIKTFNIKGANVTMPCKSAVTEYMDELSPAARIIGACNTIVNDNGKLV
                     GHITDGVGYVRNLKENGIEVKGKKITIMGAGGAATAIQVQCALDGAREISIFNAKDDF
                     YKRAEQTVENIKKDVPECVVNLYDLEDTNKLYEEIESSDILTNATLIGMKPYDNETNI
                     KDTSVLRKDLVVTDVVYNPKKTKMIEDAEANGCKAIGGLGMLLYQGAEAFNLYTGLEM
                     PVEEVNELCFK"
     gene            17332..18549
                     /locus_tag="PC466_002330"
     CDS             17332..18549
                     /locus_tag="PC466_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2769703.1"
                     /translation="MNNKKYYPTAIALYFSYFLLGIGISILGQYKPEFSSMWGAKTLS
                     DGTLDVSIVLAVIAALGLGRLISYPFAGPISDKYGRKVSGLIGNFLHAIFFVGIVFSP
                     NFYIAYVFAIIGGAANSFLDTCVTPSCMEIFASLGTIANMFTKFTIALAQFLLPFIIG
                     FVAANSISFKVIFIVTAILIVVDAILIAVLPFPPANNVIDNKGKTVKSEKMKFTPTSI
                     ALVCIGFTCTSTFVLWLNCNQELGKLYGMADPTKIQSFYSMGVICAVLITSLLIKKYI
                     KPIRILVIYPIIALLMLLIVYFVQTPTICMLGGFVIGYSAAGGVLQLTTSTANEMFPT
                     NKGKITSIVMIASSIANYVILNIAGIITKSGGVNGPKYVVLFNVAITFVGILLALFVN
                     MRYEKEKVYDYDV"
     gene            18785..20650
                     /locus_tag="PC466_002331"
     CDS             18785..20650
                     /locus_tag="PC466_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIRAN domain-containing protein"
                     /protein_id="HDF2769704.1"
                     /translation="MENVFKRLQEFNGYDGYKESFEMNYLCIYESIPLREQVELANNL
                     VDEILNMYKSESNEIYLLEDSNSKSLICYFEIFMKKINTLVKEMIIDEKWLYKLTKEL
                     IYKSKKVEYVKLGLVLSEKYLNVENLREVVDTFSKSGEYVFYLSNTIKKLEFYNTYLF
                     NLSKKATGSIKVFAIVNMENLDSKINSYLIEDGYKDTKYERLLMNYIISIVDLNEYLE
                     KRDLDKEKINNLARLICNYLLSVEFKYIGNKLELVNRFLPTVVNYGTNFESLYSIFLI
                     AINVLKDENIEYNKIEFEKEINDILLSEKWKNIYFEALRDASGKTEDIIKMSEIYDVN
                     LSFDDLLPYLNRDIRDFEVYWHISKKGTTSSRLKLLNFFEETFKIDDLIGKMKDIEKD
                     KLTQEYYDDMLFFIVLKGSKSLYPEGKNISLKGIFGNINEVRKESINILKRYREKLSL
                     EELKIVKEAYEKEKNVILKDELRRVLYESNNLKKEFVNIEKIKVDEHGKDIYLTSIAV
                     AGSRFRNREYLEKELEKSKIYYLTREKDNLYDEKAIKIVGETGYVIGYVPRKENYILS
                     NLLDGGKLLYCRVTEYNLYEDCIYANVYLSYKDVIETVENSLKMVLDKSRIKLIN"
     gene            complement(20828..22192)
                     /locus_tag="PC466_002332"
     CDS             complement(20828..22192)
                     /locus_tag="PC466_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2769705.1"
                     /translation="MSQLLIKNAYLITMNADREVYETGSILIENNIIKNVGKFDINIV
                     DKDAEIYDAKGKILMPGLVNTHVHLSQQLGRGLADDVVLLTWLRERIWPYESSFNYED
                     SLISSTACCVELIKSGVTTFLESGGQYVDAMVEAVDKTGLRACLAKSVMDTGDGLPEA
                     WQKTTDEEINTQLDLFHKFNNTSNERIKIWFALRTIFNTTEELLIRTKELADKYNTGI
                     HMHIAEIADEISFVKQNNGVGTVEYLDKLGVLGPNLLAAHTVWLTHKEIDLFRLHDVK
                     VSHNPGAAMKVVLGFASIPEMLEKGIPVSIGTDGAPSNNRMDLMRDMYLTSLIHKGRT
                     LNPTVVPAEEVLEMATINGAKCALLEKEIGSLEVGKKADMIILNPDTIHCLPMHNPIG
                     NIVYSMTSENVDSTICDGKWLMKERKVLVVDESELLNKVKKQASKIKDKAEVKIPSKF
                     KIIK"
     gene            complement(22339..23682)
                     /locus_tag="PC466_002333"
     CDS             complement(22339..23682)
                     /locus_tag="PC466_002333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HDF2769706.1"
                     /translation="MVPNTNNVQPDGNNSSLSFLDKMFKFSERGSSLKTEVIGGVTTF
                     LTMAYIVFVNPAILSEAGMDKAALITVTILATAIGTLIFAILGNAPFALAPGMGLNAF
                     FTYSLVIGAGIPWQTGLGVVFLSGCVFFTLAVTGLRKTIADAIPRELAVASSAGIGLF
                     LAFVGLKNMGVIIANPDTIVSLADFTPTVLIALFALILMAILEYKKVKGGILISIVVA
                     TIISVIFGFVELPTAIISTPPSIAPVAFKLDIVGALKFSLIGPIFSFMFIDMFDSLAF
                     LITCCKQMGLEDENGEIKDLGRMLYADVSSTLIGSFLGTSTVTTFGESASGIAAGART
                     GLASIVTAALFLATLIFTPLLGIVPTYAAAPALVMVGVFMFESIKQIDFADSKIAVPA
                     FVTVLLMPLTYSISIGLCFGFISYIIMHVVAKETDKISITLWIIGLLAVVNLVLS"
     regulatory      complement(23755..23856)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            24186..24839
                     /locus_tag="PC466_002334"
     CDS             24186..24839
                     /locus_tag="PC466_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HDF2769707.1"
                     /translation="MTKIIKVQKPKFTGELEIIENLEDILEDIFNDEKIFNKIIENEV
                     ISDLDSVRVSFESCIFRNVSFENCNLKKIDLLDVVFENCNLSNSFFDGGSIYRVEFKN
                     SKLIGVRFDDCILKNVLFKDVLGKYSNFSFSKFKIVSILDSNFENSVFQEVKGDNLVF
                     EYTNLKKANFNGTKLSGIDFTTNNIEGIEIGIDEIRGAIFDVSQAIDLTKLMGIIIK"
     gene            24980..26251
                     /gene="brnQ"
                     /locus_tag="PC466_002335"
     CDS             24980..26251
                     /gene="brnQ"
                     /locus_tag="PC466_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HDF2769708.1"
                     /translation="MRDIFIVGFALFSMFFGAGNLMFPPFLGMESGKDWLIPLIGFVV
                     ADAGIAMLVIIATARCKGSMDDVLRRAGKGLARVMSVAALACLALLVIPRTCATTYEM
                     GIMPIFGDHGPVAKAIFSIIFFGLTLAFTIRSSKVIDIIGKYLTPALLLVLFVLIVKG
                     IISPAGPMSPEHMIDKNLFGEGISQGYQTMDALGAASMATIMLMSIIAKGYTSDKDQI
                     GMTIKAGFVACVFLAVVYGGLTYLGATVSTLYDTSIPQASLLVEITSILLYGQVGKVI
                     LGVIVALACLTTSTGLTASISTYFEGISKASYKQLVIGICVASMLISNLGVDSIIAIS
                     VPILQTIYPVLLAIVVMELAGKHIKNDNAFKGAAYVTLVISLLSAINGMTGAVPFIQS
                     LPLAGLGFNWVIPAILGGIVGNFIKSNKQVA"
     gene            26453..27640
                     /locus_tag="PC466_002336"
     CDS             26453..27640
                     /locus_tag="PC466_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3798 domain-containing protein"
                     /protein_id="HDF2769709.1"
                     /translation="MLRKITAFMLSICLIIGLTGCSLLVGKKDKEKIIDDFKVAVVTQ
                     PLSENKVQYNMVEEMTKEYEEENKIDKDKDGQTKVKQTIKHVVLPENFTSNIDSAINK
                     IVKLADDKEVQAIVVSTDQAGLLPALQKVKEKRPEIITISAPMGDDKNQLSQFVDVNL
                     GVSAEERGKVLAERSKEMGAKAFIHYASTDDLKDVNIAKRLEMIKETCKNIGLPFVQV
                     NTPNINTEEDKNKVKQFLNEDIEKQVKKYGKDINVFGVNEYMDEVILTKALELKYIVA
                     EQSNPSPIQTYPSVMGLKISEKDAQNYDKINDMISEKAKAFGMSNRLGGYPMPMDAFL
                     PSVAIYLATEMVKQDLTQEDVCDPDYLEAFTELRFGIGSEFTPLTEVLYNYQSVILSQ
                     LIY"
BASE COUNT        10879 a         3111 c         4835 g         8970 t
ORIGIN      
        1 taacttttaa aaattagttt tactaattta caatagaata ggtgtgctgg tgtggctcaa
       61 cggtagagca gctgacttgt aatcagcagg ttgtaggttc gattcctatc accagctcca
      121 gtaaagacta tgtttttagc atagtctttt tttattgttt tttattgttt gatgtatttg
      181 ttattttgta ttacatactt ttagtggcct aatttataaa ttataggtat aaaagatgac
      241 acagtttaaa attattgttt taaactgtgt ctgtgagttt taaatcaatc taccatgaat
      301 caccattctg gcatcatcaa attcataggt acatgtagaa agtgtaacta ttttatcatt
      361 gctatttacc ttaataggag atttatacaa tgatttagaa gtaatatcat ttatgtaatt
      421 ttgataatca gattcattgt taaaatttgt ttttagataa tcataatcag attctacaat
      481 ataagcagaa aaaacatcat ataaaaattc ttttccattc aaggttattt ttattttatt
      541 attgttttta aagaagtcag catctttaaa cttatttagg ttgttgaaca tagttttatt
      601 tttcatatta tgtccatata ttatgatatt tttgtcatca atagatttat ttctataatc
      661 cataaacagt gtaccagaaa tagaatcttt tttataaaaa tctttgtcaa gatagtaaga
      721 attatcttta gattgtacaa ctggataatt tatatttgta ttctcaacag aaagccaaaa
      781 tttaaaatca ctgttaatct ttgataaatc ctctttttta tattcttttt tttgaagttc
      841 tgaggatgtt ttagtatcat gattgtattt ggtaagtttt gagtatatat taaatccact
      901 gtaaagtatt actaatacta gtataatgtt aattactatt ctatataatt ttttcaatat
      961 atcacctcga gttaaatgga gtttatatat ctatattaca ctatttttga ataaatttaa
     1021 atttttagta taatattact ttgacatgta aaagaatttg tgttaacata actaagtaaa
     1081 ataaatatta agtaagccag ataatcgcat gtaatcttac atgaggaaag tcggagctcc
     1141 atagagcagg gtgctaggta acgcctagtg ggagcgatcc taaggatagt gcaacagaaa
     1201 taaaccgcca ctattgtggt aaggatggaa aggcgaggta agagctcacc agcagctagg
     1261 cgactagttg gctatgtaaa ccccacctgg agcaagacca agataggaat aaagagtgct
     1321 gctcgtactc tccggtaggt aggtcgcttg agcctattgg tgacaatagg cctagaaaga
     1381 tgattatcta atacagaact ccgcttatag acttgcttaa ttatttcgat agtcaaaaac
     1441 atcagtttaa actgatgttt ttttatttgt aaatttgtct aatctacttt taaaattttg
     1501 aggaatattg taatataagt tagtacagat attaaaaatg gtataatata agatagatat
     1561 aaaaagaaaa agtaaaatga tgtaaataat atgatatgat ataagatgta gcaaatttag
     1621 taaataatta tttagatatc ataatcaaat tagcaacttt gcacaatgta aatattacaa
     1681 taaaataatt gatttaagga gtgaaggttt tgagtgaaaa taatataata agaaacactg
     1741 ttttaaatgt cacagcaagt tttttaaaac aagagtctaa aataaatgaa aagctagatg
     1801 gtgttttgga aaagaaattt gaaaaagtag aatttaatga agcaaaatat gcagagcttt
     1861 taaaatttaa tatattgttt tataagacat tagcaagaaa tacagaacca cttattggca
     1921 aatggatagt agataagtac atacctgaaa tagatgaatt agaaaaagat ttagaattaa
     1981 ctacagcaaa atgtagaaag tatgtaaata aggctatgaa agagggatta gactctctaa
     2041 aagccaatga tttaaatagt tttttagctt atgataaaat ggaactatca gagagaagaa
     2101 gacgtttaga aaaggattat aaggttttaa acctatataa agacctcctt aatatatctc
     2161 ttagaaaaat aagtttagaa aagaaagaat gtggagattt atttcttaaa aatcaagcag
     2221 atgcgaaaag agaattaaaa agagaaatta tattctgtgt aaacaaaata ttagctagca
     2281 ataaagatgt ggtacctaat aatgtggaag agaataacga acaagacaaa gtagaaataa
     2341 aagcaactga aattgaggat ttgcaattag gtaaagataa ttcagaaaat gacatgctac
     2401 taaatgaaat taaaaattca aaagtaaaac atgaatcaaa atcaaatgat atagaatcga
     2461 agtttataga taagttaaat agcttaaata atgaaagtat atctcaaaca atacacaatg
     2521 aatataagaa gttatgtgga ttagaagaac ttcattctgt tgaaggatat ggttttggca
     2581 aagaaattat taaagatttt gcttgtgcaa cggttgtatt agaattttta aagagaagaa
     2641 atagagacct tatagaaggt gcaatgagac tgactataat tggagaattt ggtcctgaaa
     2701 attttaagga atttgtggac tatgtaatta aaaataaaac agaaattagt gaagatacat
     2761 ggaataaagc acagaatcta ataaaagata actatagtga attagaaaat catgaaattg
     2821 catcaaaaag aactagaaga aataaagata tcgatattga agaatacatt tacatgataa
     2881 aaaatgcaga taaagatatt tgctttagaa gtagtatttc aatagaagat gatgctgaag
     2941 aaggggctaa agaagaagta gatagtaata atcaagatat aggtgacgtt gtagaagata
     3001 aagatactac agataaagag tacgacagca ataaagaaga tataattgaa ccagaaaata
     3061 aaaagagtaa aaagaaggct aaattatttg gatttattaa aaaagacaat gaagaagttg
     3121 aacaagaaga agagaattta aatgatattt ctcctgatat aattttagat aaaccagttg
     3181 aaaatcatca agcaaaatca gaagaaatag agcaaaatga attaaaagaa ataaaacaag
     3241 aagaaccaag tcaacatata gaagaagaac gtagtgtaaa aatagaaaaa ccaataaata
     3301 ataacttaga tgaaaaagta tcttcaaata atgaatcgaa gcttgaaaaa gaaagtaaaa
     3361 acttagaaga taaaaaagca aaagaaataa aagaagaaaa attagaaaat gaaaaatcag
     3421 tagtaatacc tattaaaaag aaagaaaata gtaataaaaa atctaaaaat tcttctaagg
     3481 acaaatatag agaaaacaag aaagaaatga aaaattatgt atcagataaa gaagattctt
     3541 tagatgatga agaggttgtt tctaagaaga gtagattaaa agaaactatt atagcagtag
     3601 ttatagtggt tattgttggt gtaggatatt ttataacagt aggcaacaat aagaaaaatg
     3661 ataaagagaa tattccaaag tcatcaactc aacaacaagc taacaataaa ttaactgagg
     3721 aagagaaaaa agcacaagct gaaaaagaga aaaaagaagc agaagaaaag gcaaaagctg
     3781 aaaaagaggc tcaagaaaaa gcacaagctg aaaagaaagc aaaagaaatg gaagcatata
     3841 aagatggtaa aggtgtatat tacactgttt atgcaggttc acttaaagtt gaaaaaacag
     3901 caaaagaaac agcaaaagaa tatgaggcta aaggtatttc ttcaacaata attcaagaaa
     3961 atggatacta taaaataaaa ataggtgatt attctcaata tggagaagca caagaaaaat
     4021 gtaatgaact agctaagaaa tctattgata catatatagc tatgtatgat aagtactatg
     4081 attataagtt agaagaatta aaagaatcag ctccttcttt gagtgctgaa gaacttaaac
     4141 aaaaatatga agatttaaga agtgagttaa agaacaaatc tggatatcgt gaatatgtta
     4201 aacatttaga taaactttat gaagaaatag ttgaaggtgc ttagagcatt ataaaaaagg
     4261 agaaactatg tctcagaata aaaagtatta aaaaaatatt atttgttttg agacatttta
     4321 ttcaccttta taaaatactt ataattctgt ttaggtggtg aaggtatgtt gaaattagga
     4381 gaaaaaatca tatatgagct ttctgatggg tttgagctta gtggcataag tagatactca
     4441 aaagaatata aaaagcttca tataacaaat ctagggaata taataatcag caaatcagat
     4501 gaagttaatg aggatacagg tgtaaaatat atatatagtt tttcagacaa taaagaaaaa
     4561 ttagaggcag ttttagaaga ttctcaaata attgtctatg gaaataactt gcctttttac
     4621 ataaaaagtg aaaattcaag taaaaatgtt acagcaaatt tgactatgaa aataactttg
     4681 gatgaatatg atttaatctg caaaagtcaa agagaattta tattctatct aaaggataat
     4741 atgactatat taagtttaga tgacaataag ttttatatgg gtggaattaa taaagataat
     4801 gagaagttta tatttatcag tgggaaaaat agatttgaaa taaattttga tgatatagaa
     4861 agatacattt tagaagataa aagagtgtca ttgaagggat actttcatat ggaaagagag
     4921 gggattatag taaggtctgt atctatattt aataacaata tagatagtgt agttccatct
     4981 gatttaaatg agagagttaa agataaccaa aaaataggaa atcttcctaa agattgtgat
     5041 atagtattct gcaagatatc aggaaatata gatggatttg attataaaaa cacaaacatg
     5101 cttttagtaa aatatcaaga ccaattaatt tttataaata agaaatctaa gaagactatt
     5161 gtaaagtcag cgaaagataa ttgttctaag ttaaatttag gagaagatat aatattatat
     5221 gataataaaa atgtatttaa cctacatata aatgataaaa atagagaaat tatgcaaata
     5281 gatgacttaa aagatataga aaatgaaata gtgggatata cattaaaaca tgctccattt
     5341 tttattcaag aagatttcga tagcttgact attctaaagt cttttcaaaa agaaatcata
     5401 tctataaaaa atagtgatat aaaagacatt gtaattaata aagaacttga aaacgaaaat
     5461 tctaattttg tagaaacgga aataaaattt aataatcaaa aagtactttt aaacttaagt
     5521 aaaaatatgg ttcaaaaact tatgcaagat gtatttatat atgcaaagca acctctactt
     5581 aaagaaaatt ctattgaagt gatatataag aattggtcta aagctatgaa tgatatgata
     5641 atatttaatt tttttggaaa tatttactat atgaaatctg aatttgataa gattttagaa
     5701 aaagagttaa atgatgaaat aagaatagaa gttataaatt cactttataa gcaaatacaa
     5761 gaacaaagaa acaatttaga tttattgtca gcatatatgc caagaatatt agaaaatcaa
     5821 gaaatagatt tgtttgaaaa gtataatact aaacttgatg tacaagtgtt taagcagatt
     5881 aaaaatctat tgtctgactt atcatataat ataagcagtt atttaaatga agttgaaaaa
     5941 agtttagaca atatcatctt tgtaatttca ggagaagata agaagaaata caattataga
     6001 atgttaaaag aaagtgaaag tgcaagtctt gatgtatttt taaaacaagc catatcaaga
     6061 ttaaaccatt tagtagaaaa tatgtatcct tattatgtag atgaaactag tagggaaatg
     6121 tttaagttat ttgagttatt gtggaaaaac tatagaaata ttgatgatga tagtataaaa
     6181 gaaatattat tcgagagaat aacaaataca tatgtattta aacaattgac attaaataat
     6241 agtacaaaag aaagaagaaa agacataatt gaaaaaatat ataactctgt tgattatgga
     6301 accaataaac tagatgaaaa tatgtttttc acaggaggaa taaagtatgt caagtaaata
     6361 caatgtttgg acttttaact atgagttctt aggattggac tcaggggatg aaaaaaataa
     6421 tgaagtttat tacgagattg atttagatga aattttaaat gaaaactata tagatgaaga
     6481 tatagatagt ggtttagatt ctgatggaaa tagtatttta ggagaattaa tatcagaaat
     6541 ggatatagat gaggatgtca gtgttgatat gacatatcaa gaactagaag ttgacttaga
     6601 agatttagat tcttatctag atgaagatat agatagtgat ataaaaggca tcttagatga
     6661 aatttagtac ctgtataagt tttggataaa atataaacaa tacaatatta acttataaaa
     6721 ctaaaggtag atgaaatttc atctacctta tattatctta tagcattaaa tattgggata
     6781 atatagagtt tgaagaaaaa gtataaatat ggtatattaa tttggtacaa tagaaaattt
     6841 acgaagaagg gtgaaaaaat gcagatgaca gttaaaaaag caataatacc agcagcaggg
     6901 ctaggaacca gatttttacc agcaacaaaa tcacagccca aagaaatgct tcctatagta
     6961 gataaaccaa ctttacagta tataatagaa gaagctatag aatcgggaat tgaagaaatt
     7021 cttataataa caggtagaaa taaaaaatct atagaagatc attttgataa atcagttgaa
     7081 ttagagttag aactagagca aaaaggtaag acagagatgt tagaaatggt aagagacata
     7141 tcaaatatgg taaatattca ttatataaga caaaaagagc caaaaggtct tggacatgca
     7201 atttactgtg caaaaagttt tataggtgat gaaccttttg ccgtattatt aggtgatgat
     7261 atagtagatt cagatgttcc gtgcttaaaa caattaatag atacttataa tgagtataaa
     7321 acaactgtat taggtgttca aaagatagct aaagaagata ctaataaata tggtatattg
     7381 gatgtaaaac atatcgaaga tagagtatat aaagttaaag atatggttga aaaacctgca
     7441 attgaagaag ctccatctga tatagctata cttggaagat atataataac tcctgcaata
     7501 tttagtatat tagagaaaca gacacctggt aaaggtggag agatacaact gacagatgca
     7561 cttcaaactc ttggaaaaca agaggctatt tatgcttata actttgaagg tagaagatat
     7621 gatgtgggag ataagattgg ttttttagag gcaacaatag actttgctct aaagagagaa
     7681 aatttaaaag atgatttaat ggactatatg agaaaaaaag taagtgaaaa ataaaatatt
     7741 agaaaagagg taattacaat ggcagtttta gtagctggag gagcaggata tataggaagc
     7801 catacagcaa tagaactttt agaatcaggt tatgaagttg ttatagttga taacttaagt
     7861 aatagcaact caatagtggt tgatagaatt aaggaattat ctaaaaaacc agtaaaattt
     7921 tataatattg atatcagaaa taaagatgaa atgcatgttg tatttaaaga aaataatatt
     7981 gaatcaatta tacactttgc agctttaaaa gcagttggtg aatcagtaga aaaaccaatt
     8041 gaatattaca gcaataatct aataagtacc ttaaatttat ttgaattaat gagagaatat
     8101 ggtgttaaaa agtttgtatt tagttcttca gctactgtat atggagaccc acatacttgt
     8161 cctatattag aggatttccc actttctgta accaatccat atggaagaac taaacttatg
     8221 atagagcaga tgttagtaga tatatcaaaa gcagataagt cattggatat agctctttta
     8281 agatacttta atccagttgg tgctcataaa agtggtagaa taggtgaaga accaaatgga
     8341 gttccgagca atctaatgcc ttatataaca aaaatagcag taggtaaatt gaaggaattg
     8401 agtgtttatg gtaatgatta tccaacacat gatggaactg gagttagaga ctatatacat
     8461 gtattagatt tagctgctgg tcatgtaaaa gcattacaaa aattagaaga aaatccagga
     8521 cttgttgttt ataatttagg aactggaaag ggttatagtg ttcttgattt agtaaaagca
     8581 ttttctaaag caagtggaaa agaaatacca tataagattg taggaagaag ggctggagat
     8641 gtagccatgt gttatgcaga ttcttcaaag gcagaaaaag agcttggatg gaaagctaag
     8701 tatgaacttg aagagatgtg tgaagattca tggagatggc aaagtatgaa tcctaatggg
     8761 tatgaagagt agaatacata cttatatgta taaatgtaac aaatttgtaa atataaggta
     8821 ttggtaattt tatgttataa ttagacacat gtagtaatgt ttctaaaaga gggggaagtt
     8881 atagtgaaaa aaagtctaaa aaagtattta gtactagcac tgactttagt tttagtattt
     8941 gcatgtggcg taccagaatc aagcgcagcc agtaaacatg tgattatagt aaattcaaga
     9001 aagaatactc taggatattt tgtaaataat aaacttgtaa aagaatttag agttgcaaca
     9061 ggtaaaaagg ggtcagaaac accaacaggg aaaacaaaag tagttaacaa gataaaaaat
     9121 agaccatatt ataaaggtaa tatacctgga ggaagtccaa gaaatccatt aggagataga
     9181 tggatgggat tagcattaaa aggaacttat ggagatacat atggaataca tggaaataat
     9241 aatgagagtt ctataggaaa gcatatttct ggtggatgta taagaatgca caataaagat
     9301 gttagatggt tatttgacca agttcctgta ggttcagatg taattataga ttatagtaat
     9361 gacagctatg taaagatagc ggcaaaatat aagataaatc taaatcaaac aggatggaaa
     9421 acagaaaatg gtaagaagta ttatgtaaaa tctgatggaa cataccaaaa gaatagttgg
     9481 ctaaaagtaa atggaaaaat gtattacttt gatgcttcag gagtaatgca aacaggatgg
     9541 aaagcaatta ataacaaaaa atattattta ggaactgatg gagcaagagt atctggatgg
     9601 aaagtaatag acggaaaaac ttattacttt aactcagatg gagtaatgca aacaggatgg
     9661 caagaaaaga atggaaagaa atactatcta ggatctgatg gtttatcagt aacaggatgg
     9721 caagaaatag atggtaataa gtattacttt gacaaaacag gaataatgca gacaggatgg
     9781 caacaaatag atggtaagtc ttactattta gacaaagatg gaaagatgct aactggttct
     9841 caaaaaatag atgggaaaga ttatactttt aatgaagatg gaactataaa tcctacatgg
     9901 gatacaatta taggtgcaaa tagatttgat acagctaaaa agataagttc agttggaaac
     9961 tggaatgctg atagttcaga tactgtaata ttagtaaatg gtaatgcaat agctgatggt
    10021 ataacagcaa ctcctttagc aagtagctat gactcaacaa tactacttac taatacagct
    10081 aatttaccaa ctgaaactgt tgaagaaatg aagttattag cacctaaaac agtaatcttg
    10141 ataggtggag aaaatgcaat aagttctaaa ttagagcaag aaataaaaac tactttcaac
    10201 acagagacaa agagaatagc aggtcaagat agatatcaaa ctgctacaag aatagctgaa
    10261 gaacttggaa atcgagaaga aataaaaact gcatatatgg tttctggaaa tggggaagca
    10321 gatgctttat ctgtagcttc taaagctggg gaagaaaaac aacctataat attagtcaat
    10381 aaagatggaa ttacagaaga atcttataaa tggctaacag aaagaaaatt agaaaatgca
    10441 tactttatag gtggaccaag tgcaattaac gattcagtaa tagcaaaaat gaatgatata
    10501 actactgaag atatttcagg aaatagaata tatggagata gtagagtaga tactaatgcc
    10561 aaagtaatag aaaaattcta tggagatact gatttacagg ctgtattagt tagtaaatca
    10621 gatgctttag tagatgcttt atcagctgga ccattagctg taaaattaca ttcaccaata
    10681 gttttaatgg ataattcagg attatcatta gagcaacaaa gagtatttgc aaataaaaaa
    10741 gttgaaactc cttatcaaat aggaggcgga gtatcttata tagtaatgga taaattaatg
    10801 gatattcttg caaaatagta aaaatatata ttgaaaaata attataattg agatgtgaaa
    10861 ttcaatcaat aaaagcttga ttgttttaca tctcaatttt ttagtataaa attaagttta
    10921 agttatataa aaatcttgga atatttttaa aactcatata aaatgaatat agatgctatc
    10981 atcatatgtt aagagggtga gtaagattat aaagaaaaaa tatataatgt ttattgatga
    11041 aagtggaaga gctgatataa atcatgaaga cccatttaca ttgacaggag taatttttga
    11101 atataaatat gcagtaagtc aaggcgatta tgtatgttct ttgaggaaag aaatggatgc
    11161 atttaaagag tattgttttg gaaccagtaa cataggaata catttgacag atatatcaag
    11221 aaaatcaaga gcatttgaga agtttgatga ttcacagatt aagttattct atgatgagtt
    11281 gcctttattt ctatctagat tagagtgtac tataatatca gtaacagtag ataaagctag
    11341 attaaagaaa tattatgcac cttcaaagga accgtatgtt gtggctttta tacatgttct
    11401 tcagaatttt tattcatttg taaataatga aactgtagaa tctgcacgaa tagttataga
    11461 gtcaagggat gatgtctcaa acttaaaagt acaaaaggcg ttttttgatg tatttaataa
    11521 tggaacaata tacttagata tagatgaaga attaagagat aaggttaagg gttttataat
    11581 tgccaaaaaa gaagatgctg actatagaga aggtttagaa atagcagata ttttatgtaa
    11641 tcctcttagc agagcaagaa gagggttaat agaagctaat ccaaagtgta tgcaatatgg
    11701 agaaaaaaac aaaatattca aatctgtcag aaacaaaata tatactccaa cgagtgtgaa
    11761 tgatataaga aattggggat ttaaagaagt tcctattgta gagcctgttg gaccatggct
    11821 tgaaaaaatg cgttagatac aattgacaaa tttaaaaaaa tctgatataa tgtaaataac
    11881 ctagttattc aggaactgaa tccagttgct gttgtataac gataattact gagactcgga
    11941 tgccgactgt cagttaggaa tctatacttt taaaagtata gattttttta ttttataaaa
    12001 agaataaaag aggatattta aaaataaccc ctttattaat aaattataat tgagcgtttt
    12061 taatgacaaa gtttttaaag tttttaattg caggaggcaa atatctatct tttataaatg
    12121 ctaagtaaaa gtttctttcc caacttgggt gaataatctg aattactttt acttttgtaa
    12181 agctaagcat attcatattt gggactacag caattccgaa attttttgca actaatccag
    12241 caattacttg gtcttcctct acttcataga ctatattagg ctgttgattt atttttttaa
    12301 acatatcatc aattatatat ctaagaccac ttctctgatt aaatactatt tgaggataag
    12361 gtatggtttc ttttaaatct atagtatcct ttgcagctag tggatgacta tatggtacaa
    12421 ttagtactaa atcttgtttg gcaacaggta taaattcaat tcccttttct ttttcaagtt
    12481 tcgaacaaaa tgcaatatca tattttcttt ctttaagacc ttgaataatg tcagtagtta
    12541 caccagtatg aaatttaaaa tctattgatt tagcaggatt agattttaaa aatttatgca
    12601 ctatgtctgg gataaaatca gtaccaagtg ttctaagaaa agctaagtct atttgtcctt
    12661 caccagtacc agttattttt aatgatttta cacttgaatc taaaatttct aatgattttt
    12721 ccacatcttt taaaaatatt tttccatact tagtaaggac tatatttcta ccttcttttt
    12781 caaatagagc caccccaagt tcattttcta gtaaagaaat agcatgactt aagcttggtt
    12841 gtgttataga taaattttct gccgcttttg tatagtgttc taaatgtgcc aatgtaacaa
    12901 aatagcgtaa gtgatataaa ttcaattttt gttcatcctt tcataggtat ttttatttat
    12961 atatttgtag aagttaacct ttaagatatt tttacatttt tattatatat gattatagag
    13021 taagaataaa agcttttaaa aaaatttatc gttttttgtc tgaattataa gataaatata
    13081 tttatacaac ctaatagaaa aatacaagaa ttatcttata aataaaatct ataaacaaaa
    13141 tctatgaatt aataggaaat tatcaatttg ttattagtaa agtctcgtga tacaataaat
    13201 ttataaaatc tagataaata gaaatcaaaa aatactttta tttttaaggt aaaataatac
    13261 tactagtagg ataaataaaa atataaaatc aaagatacta ttaattataa agaaaataaa
    13321 gggggcaaat ttaagctatg aataatcaaa aaaatcttaa tattccaatt acaattagtt
    13381 cttatacatt gggaacagaa gtttcattcc gtgatagagt tcgtattgca aaagaagctg
    13441 gatttgatgg tattggattg cgtgctgaaa attatattga tgcaaaaaat gcaggtgtta
    13501 cagatgaaga aatgattgca attcttaatg aatatgatat gaaagttaca gaagtagaat
    13561 atataactca atggggaaca gaagaagata gaactgaagc tcaaagagaa aaagagcaaa
    13621 atgtttatca tatggctcac ttatttaatg ttaaacatat aaattgtgga ttattagaga
    13681 tgataccaga agaacaaatt ataactgcat tgggagaatt atgtgacaga gcaggtgaac
    13741 ttattatagg tcttgagttt atgccatata gtggtgtacc agatttggct actgcatggc
    13801 gtgttgtgaa aggatgtaat cgtgaaaatg caatgcttat attagatact tggcactggg
    13861 ctagagcaaa gcagacagca gaggaccttg cacctgttcc agcagataag atagtatcaa
    13921 ttcaagtgtg tgatgtttta gaaactcctt atgaaaaact tagggatgaa tcactacatg
    13981 accgtttggc tccaggtgaa ggatatggaa acacagagga atttgtgaaa ataataaaag
    14041 aacacaatat atcaccaaga gtcatagggg cagaagtaat atctgattct ctaatatcta
    14101 aagggttatc cactgctgct gaaactgtat ttaatgcaac taaaaaagtt ttggataaag
    14161 catggtctga agtatctcca aaataaactt atataatata aaaatataca gagtattata
    14221 atataaaact tttaaatata aaacttgaaa ggaaggaaaa ccttatgaag attagttcta
    14281 tgtttacacc tataagaatt ggttcaatga cagttccaaa tcgttttgta gttcccccta
    14341 tgggaaacaa ttttgcaaac acagacggta ctttaagtga aacttctaag gcttattatc
    14401 ttgagcgtgc tttaggtggt tttggattaa taactataga atctagtgtt gtagacaaaa
    14461 aagcaaaagg aggtcctcgt aagccttgtt tatatgatga tagcacaata gatagtttta
    14521 aaaatgtaat agatgcttgt catgatgcag gttcgaaggt atctatacaa ttacaacatg
    14581 ctggttctga aggaaatgaa aaagtagcag gacatccatt aaaagctgct tctgcaatac
    14641 ctgcatcaaa tggtcgtaat acaccactag caataacaac agaagaaata tatgaactta
    14701 tagaatctta tggagatgct gcattacgtg cacaaaaagc tggtgcagat gctgttgaag
    14761 ttcactgcgc tcatggatat ctggttagta gttttatatc acaaagaaca aataagcgtg
    14821 tagatgagtt tggtggatgt tttgaaaata gaatgagatt acctcgtctt atcattgaaa
    14881 atatacgtaa aaaagtagga aattctctag caatattatg tcgtataaac agcactgatg
    14941 atgttccagg aggaattgat atacatgata gttcagtaat agcagcatat ctagaaggtt
    15001 gtggaataga tggacttcat gtttcacgta gtatacatat acatgatgaa tatatgtggg
    15061 ctcctacgac tttacatgct ggattcagtg cagaattagt tactgaaata aaaaaagctg
    15121 ttagtatacc agtaataaca gttggacgtt atacagagcc acagtttgct gagttaatgg
    15181 tcagacaagg aagatgtgat ttagtagcat tcggtagaca aagcttggct gacccagaaa
    15241 tgcctaataa agctaaaaat ggaaaactag acgaaatgat accatgtatt gcatgcttac
    15301 aaggatgtgt accaaatatg ttccaaggaa aacctatagc ctgtcttgca aatcctatat
    15361 taggacatga agcagagctt aagccagctg aaattagcaa agaagttctt gttgttggtg
    15421 gaggtgttgg aggtatgctt gcagcatggg tatgtgctaa aagaggacat aatgtaactt
    15481 tagttgaaaa atctgaagtt cttggtgggc aaatgcgttt agctgcatat cctccaggga
    15541 aaggagatat tactaactta gttagaagtt atatttcaaa atgtaatcaa tatggtgtaa
    15601 aaatatgtac taatacagaa gctacagtag aacttataaa ggagaaatca cctgatgtag
    15661 ttattatagc tactggagca actccacttg tacttcctat accaggaatc aatgattcag
    15721 gattaattca tgctgtagac cttcttgatg gtaaaaaatc ttgtgggaaa aaagtacttg
    15781 ttgttggagg tggaatggtt ggatgtgaag tggcagcctt ccttggagaa caagaacatg
    15841 aggttactgt tattgagctt agagaagaag ttggtgcaga tgtaatttca gaacaccgta
    15901 aattccttat gaatgatttt gaaaattata atatacatac cattactggt gcaaaagttt
    15961 ctaaatttta tgatgatggt gtcgactatt tacttacaga tggcacagag catgatttaa
    16021 aaggttttga ttcagtagta cttgctatgg gttctcgtaa ttacgaccca ttaagtgaag
    16081 ttataaaaga agttgtaaaa gaaacttata ttgttggtga tgcagtaaaa gctcgtaggg
    16141 cattagatgc aacaaaagaa gcttttgaag tagcattaaa tatataaata ataaataaat
    16201 ttttctttgt aaataactga ataggttatt tgcaaagaaa atgataatat tgggaggaaa
    16261 ttatagttat ggaaatttca ggtagaacag gattatttgc attaataggt acaccagttg
    16321 gtcactctaa atcaccagtg atgtataatt atagttttaa gaaattagat ttagattata
    16381 gatatttagc ctttgatatc acagtagata aggtaaaaga ggcactttta gcaataaaaa
    16441 cttttaatat aaaaggagcc aatgttacta tgccatgtaa atctgctgtt acagaatata
    16501 tggatgaact ttctccagca gctcgtataa ttggagcatg taatacaatt gtaaatgaca
    16561 atggaaagtt agttggtcat ataacagatg gagtaggcta tgttcgtaat ttaaaagaaa
    16621 atgggataga agttaaaggt aaaaagatta caattatggg tgctggtggt gcagcaactg
    16681 ctatacaagt acaatgtgct ttagatggag caagagaaat atctatcttt aatgctaagg
    16741 atgattttta taaaagagca gagcagacag ttgagaatat aaaaaaagat gtaccagaat
    16801 gtgttgttaa tctatatgat ttagaagata caaacaaact ttatgaggag atagaatcaa
    16861 gtgatatatt gacaaatgca actcttattg gtatgaagcc ttatgacaat gaaacaaata
    16921 taaaagatac tagtgtttta agaaaagact tagtagtaac agatgtcgtt tataatccta
    16981 agaaaacaaa aatgattgaa gatgctgaag ctaatggatg taaggctatt ggtggattag
    17041 gaatgttatt ataccaagga gcagaagctt ttaatctata tactggatta gaaatgcctg
    17101 tagaagaagt taatgaatta tgctttaaat agataagagt gatatcttaa acaatgaaaa
    17161 aacatacgta tttcaatatt tttaataata aattacaaat tgtcatagtg ggttttgcat
    17221 catagtccag ttaaatttga agctttaact gactatactt taaatccatt atgaggatga
    17281 gtttattgta cacaaaaatg ttaataaatt aacaagaatg ggagaaaaat tatgaacaat
    17341 aaaaaatatt atcctactgc catagcgttg tatttttcat attttttact tggtattgga
    17401 atttcaattt taggacaata caaaccagaa ttttcatcaa tgtggggggc taaaacacta
    17461 tcagatggaa cattggatgt aagtattgtt ttagctgtta ttgctgcact aggattaggg
    17521 agacttatat cttatccatt tgcaggacct atttcagata agtatggaag aaaagtaagt
    17581 ggtcttatag gaaactttct acatgcaatt ttctttgttg gaattgtatt ttcaccaaat
    17641 ttttatatag catatgtatt tgcaataatt ggaggggcag caaattcatt cttagatacc
    17701 tgtgtaactc cttcttgtat ggagatattt gctagtttag gaacaatagc aaatatgttt
    17761 actaaattta caatagcttt agcacaattt ttgcttcctt ttataattgg atttgttgca
    17821 gcaaattcaa tatcatttaa agttattttt atagtaacag cgattcttat tgtagtagat
    17881 gccattttga tagctgtgtt accatttcca ccagctaata atgttattga taacaaaggc
    17941 aaaacagtta aatcagagaa gatgaaattt acaccaacaa gtatagctct tgtttgtatt
    18001 ggatttacat gtacatctac atttgtatta tggttaaatt gtaatcagga attgggtaaa
    18061 ttgtatggga tggctgaccc tacaaaaatt caatcctttt actcaatggg agtaatatgt
    18121 gcagtattaa taacttcttt acttattaaa aaatatatta aaccaataag aatattagtt
    18181 atatatccta taatagcttt acttatgcta ttaattgtat attttgttca aactccaact
    18241 atttgtatgt tagggggatt tgtaataggt tattcagcag caggaggtgt tcttcagtta
    18301 acaacgtcaa ctgcaaatga aatgtttcca actaataaag gaaaaataac atctatagtt
    18361 atgattgcat ctagtatagc aaactatgtt attttaaata tagcaggtat tattacaaaa
    18421 tcagggggag ttaatggacc aaaatatgtt gtattgttta atgtggcaat aacatttgtt
    18481 ggaattttac ttgcattgtt tgtaaacatg agatatgaaa aagaaaaagt gtatgattat
    18541 gatgtctaat attagtataa tatatgcata gagaagtcta aatctaggat agatttttat
    18601 taaaagtaat taaaattaat aaggatatta tttacagtta taagataggg tatttacata
    18661 attaataata aggatattac tagaatttca atttctagta atattttttt gcgtataaat
    18721 gtaaacttga cgaaataagt agtataatca atataaatta catcatgtaa aggaggataa
    18781 tttggtggag aatgttttta agcgattgca ggaatttaat ggttatgatg gatacaaaga
    18841 atcatttgaa atgaattacc tatgtatata tgaaagtata ccgttaagag aacaagtaga
    18901 acttgcaaat aatctagtag atgaaatttt aaatatgtat aaaagtgaat ctaatgaaat
    18961 ttatttattg gaggatagta attctaagtc tttaatttgt tatttcgaaa tttttatgaa
    19021 aaagataaat actttggtaa aagaaatgat tattgatgag aaatggttat ataaattaac
    19081 taaagaatta atatataaga gtaaaaaagt tgagtatgta aaactagggt tagttttaag
    19141 tgagaaatat ctaaatgtag aaaacttaag agaagttgta gatacatttt ctaaatctgg
    19201 agaatacgta ttttatctga gtaatactat taaaaaactt gaattttaca atacatattt
    19261 atttaattta tctaaaaagg ctacaggttc aataaaagta tttgctattg ttaatatgga
    19321 aaatttagat tctaaaataa attcctatct aattgaagat ggttataagg atacaaagta
    19381 cgaacgatta ttgatgaact atattatttc aattgtagat ttgaatgaat atcttgaaaa
    19441 acgagattta gataaagaaa agataaataa tttagcacgt cttatatgca attacttgct
    19501 aagtgtagaa tttaaatata taggtaataa attagaatta gtgaatcgat ttttacctac
    19561 tgtagtaaat tatgggacta actttgaaag tttatattca attttcctaa tagctataaa
    19621 cgtcttaaaa gatgaaaata tagagtacaa taagattgaa tttgaaaaag aaataaatga
    19681 tatcttgctc agtgaaaaat ggaaaaatat atattttgaa gcattaagag atgctagtgg
    19741 aaaaacagaa gatattataa aaatgtcaga aatttatgat gtaaacttat cttttgatga
    19801 cttgttgcca tatctgaata gagatattag agattttgag gtatattggc atatatctaa
    19861 aaagggaacg acaagttcta gattaaaatt attaaatttt tttgaagaga cgtttaaaat
    19921 agatgattta attggaaaaa tgaaagatat agaaaaagat aaattgactc aagaatatta
    19981 tgatgatatg ttatttttta ttgtgcttaa aggaagtaaa tcactatatc ctgaaggaaa
    20041 gaatatatct ttaaaaggaa tatttggaaa tataaatgaa gtaagaaaag aatccataaa
    20101 tatcttaaaa agatacagag agaaactatc tcttgaagaa ttaaaaattg ttaaagaagc
    20161 gtatgaaaaa gaaaaaaatg ttatattgaa ggatgaatta agaagagtat tatatgaaag
    20221 taataattta aaaaaagaat ttgtaaatat tgaaaaaata aaagtagatg aacatggtaa
    20281 ggatatctat ttgacttcaa tagctgttgc tggttcaagg tttagaaata gagaatatct
    20341 tgaaaaagaa ttggagaaga gtaagatata ctatttaact agagagaaag ataatctata
    20401 tgatgaaaaa gctattaaaa tagttggtga aactggatat gtaataggct atgtcccaag
    20461 aaaagaaaac tatattttga gcaatttatt agatggagga aaactgctgt attgtagagt
    20521 aactgaatat aatttatatg aagattgtat ctacgcaaat gtgtacttga gttataaaga
    20581 tgtaattgaa acagttgaaa actctttaaa gatggtttta gataagagta gaataaaact
    20641 tataaactaa gacgtttata tattgcttag atgatgtaat cctaactgat tggttatttt
    20701 ttctggaatt atggtgtatt ttatgagcaa tgttaatgaa tataaaataa aaaaacaatt
    20761 gttttgtata tatgatgtgt ataaatatat ttatatattc atatttacaa aacaattgaa
    20821 atttatgtta ttttatgatt ttaaatttag atggaatttt aacttctgct ttatctttta
    20881 ttttagaagc ttgtttttta actttattta ataattcaga ttcatctaca actaatactt
    20941 ttctttcctt catcaaccat ttaccatcac aaatagtaga atctacattt tcactagtca
    21001 tagaataaac tatatttcca attggattat gcattggtaa acaatgaatt gtatctggat
    21061 ttagaataat catatcagct ttttttccta cttcaagact accaatttct ttttctagta
    21121 aagcacattt tgctccattt atagtagcca tttctaagac ttcttcagct ggtacgacag
    21181 ttgggtttaa agttctacct ttatgtatta gtgatgtaag atacatatcc ctcataaggt
    21241 ccattctatt atttgaagga gctccatcag taccaattga aacaggtatt cctttttcta
    21301 acatttcagg aattgaggca aatcctagaa ctactttcat agctgcacct ggattatgag
    21361 aaacttttac atcatgtaat ctaaataaat caatttcttt atgagtaagc caaactgtgt
    21421 gagcagctaa aagatttggt cctaatacac ctagtttatc aagatattca actgttccaa
    21481 ctccgttgtt ttgctttaca aatgaaattt catcagctat ttcagcaata tgcatatgta
    21541 tacctgtatt gtatttatca gctaactctt tagtcctaat aagcaattct tcagttgtat
    21601 taaaaatagt tcttaatgca aaccatattt taatcctctc attagatgtg ttattaaact
    21661 tatggaataa gtctaattga gtgttgattt cctcatcagt agttttttgc catgcttcag
    21721 gaagaccatc tcctgtatcc ataactgatt tagctaaaca ggctctaagt ccagttttat
    21781 caacagcttc aaccatagca tctacatatt gaccaccaga ttctaaaaat gtagttaccc
    21841 cagattttat caattcaaca caacatgcag tagatgaaat caatgaatct tcatagttga
    21901 agctactttc gtatggccag attctctctc taagccaagt taaaagtaca acatcatctg
    21961 caagaccacg tcctaattgt tgggataagt gaacgtgtgt attgactaac cctggcatta
    22021 gtatttttcc tttagcatca tatatctcag catctttatc tacaatatta atatcaaact
    22081 taccaacatt ttttataata ttattttcaa taagtatact tccagtttca tatacctctc
    22141 tatctgcatt catagtaatt agatatgcat tttttataag taattgtgac ataagtacaa
    22201 cctcttttct atatattttt atatctatgt attatgataa taaattttct atacaaagtt
    22261 aatagcaaaa tcaatttata cataaattga ttttgctatt tataaattta aaatattgac
    22321 ctagaactat ttaaaatatt aacttagaac taagtttaca actgcaagta aacctataat
    22381 ccaaagtgta atactgattt tatcagtttc tttagctacc acatgcatta ttatatatga
    22441 aataaatcca aagcataaac caatacttat actataagtt aaaggcatca ataaaactgt
    22501 aacaaaagca ggtacagcta ttttgctatc agcaaaatca atctgtttta tgctttcaaa
    22561 catgaataca ccaaccatta caagtgcagg agctgcagcg taagtaggaa ctataccaag
    22621 caatggtgta aatataagtg tagctaagaa taatgctgct gttactattg aagcaagtcc
    22681 tgttcttgca cctgctgcga taccagaagc agattctcca aatgttgtaa cagtactagt
    22741 tcctaagaat gagcctatta aagtagaaga aacatctgca tataacattc ttcctaaatc
    22801 ttttatttca ccattctcat cttcaagacc catttgttta caacaagtaa taagaaatgc
    22861 taatgaatca aacatgtcta taaacatgaa agagaatata ggtccaatta atgagaattt
    22921 caatgcacct acaatatcta atttaaaagc aactggtgct atactaggag gtgttgagat
    22981 tattgctgtt ggcaactcca caaatccaaa tataacagat attattgttg caactactat
    23041 acttatcaat attccacctt taactttttt atattctagt attgccatta agataagagc
    23101 aaaaagagct attaaaactg ttggtgtaaa atctgcaagt gaaactatag tatctggatt
    23161 agctattata acacccatat tttttaaacc aacaaaagca aggaaaagac ctatacctgc
    23221 tgaagatgct actgccaatt ctctaggaat tgcgtctgca attgtctttc gaagacctgt
    23281 tactgcgagt gtaaagaaga cacatccaga tagaaaaact accccaagac ctgtttgcca
    23341 tgggattcct gcacctataa ccaaagagta tgtgaaaaat gcatttaatc ccataccagg
    23401 agctagagca aatggtgcat ttcctaaaat cgcaaatata agtgtaccaa tggctgtagc
    23461 tagtatggta actgttataa gggcggcttt atccattcca gcttcagata atattgctgg
    23521 atttacgaaa actatgtatg ccattgttaa gaatgtagta actccaccta ttacttctgt
    23581 tttaaggcta gagccacgtt cgctaaattt aaacattttg tctaaaaagc ttaatgatga
    23641 attatttcca tctggttgta cattgttagt gtttggtacc atttttacct ccaaaaaact
    23701 ttaagatata aacaaaaaaa tatatattca tatagataga atagaacata tattcaaagt
    23761 tgatattcta ttcatagaaa acccatttaa ggtgagtttg tagaaactat tagaccgtat
    23821 tactaatatt atatgaacat tttctatttg tttttctgtt gtattatatc gtaatattgt
    23881 attatttaca ataaatataa taaaattatt cgtttttttg tcgattttat aaaaaattaa
    23941 ggttatttat tggcaagaat tactgttttc aataattgaa tatgtataag tataatgtca
    24001 attattctaa cttgttttat actattatat agaagtctat tataaatgag tttgtgatat
    24061 aattataaaa gtactgaata cacggatatt tcgtaaaaac tttttaatat atcaaatatg
    24121 tatattaagt taatatatta aaaaaaataa tatcaaaaat aatataattt atagtggagg
    24181 ggaaaatgac taaaattatt aaagtgcaaa aacctaaatt tacaggagaa ttagaaatta
    24241 ttgaaaatct tgaagatata cttgaagata tatttaatga tgaaaaaata tttaataaaa
    24301 ttatagaaaa tgaagttata agtgatttag attctgtaag agttagcttt gaatcttgta
    24361 tatttagaaa tgtatccttt gaaaattgca atttaaaaaa gattgattta cttgatgtgg
    24421 tatttgaaaa ctgcaattta tcaaattcat tttttgatgg aggaagtata tacagagttg
    24481 aatttaaaaa tagtaaattg ataggagtta gatttgatga ttgtatactt aaaaacgttt
    24541 tgttcaagga tgttttaggt aagtattcta acttttcatt ctctaaattt aagatagttt
    24601 ctatcttaga ttcaaatttt gaaaattctg tatttcaaga agtaaaaggt gacaatctag
    24661 tatttgagta tacaaactta aaaaaagcaa actttaatgg aactaaactt tctggcatag
    24721 attttaccac taataatatt gagggaattg agattggtat agatgagatt agaggagcaa
    24781 tttttgatgt gtcacaagca attgatttaa cgaaattgat gggaattatc ataaaatgaa
    24841 aaaaatattc ataaaataaa ttgggaaaac gttaacaatg tgtgaatttt taccagattg
    24901 acatttttct gaaaataaag taagattatc ttaatattca aaatattttc aaagggggta
    24961 atttagtgtg agtaagcaga tgagagatat ttttatagtt ggttttgctt tattttctat
    25021 gttctttggt gcaggaaatc ttatgtttcc tccattttta gggatggaat ccggcaaaga
    25081 ctggttaatt cctcttattg gatttgttgt tgcagatgct ggtatagcaa tgcttgttat
    25141 tatagcaaca gcaagatgca agggaagcat ggatgatgta cttaggagag ctggtaaagg
    25201 gttagcaaga gtaatgagtg tagctgctct agcatgttta gcacttcttg taataccaag
    25261 aacttgtgca acaacatatg aaatgggtat tatgcctata tttggagacc atggaccagt
    25321 agctaaagct atattttcaa taatcttctt tgggttaact ttagcattta ctattaggtc
    25381 ttctaaggtt atagacataa taggtaagta tttaactcca gcgttattat tagtattatt
    25441 tgttttaata gtaaagggta taatttctcc agcaggacct atgagtcctg agcatatgat
    25501 agataaaaat ctatttggtg aaggtatatc acaaggttat caaacaatgg acgctctagg
    25561 tgcagcatct atggcaacta taatgttgat gtctataata gctaaaggat atacatcaga
    25621 taaagaccaa ataggaatga ctattaaagc tggttttgta gcctgtgtat ttctagcagt
    25681 agtatatggt ggtcttactt atttaggtgc aacagtttca actttatatg atactagtat
    25741 acctcaagca tctttattag ttgaaataac tagtatattg ttatatggtc aagtaggaaa
    25801 ggtaatttta ggtgtaattg tggcacttgc ctgtctgact acttctacag gtttaacagc
    25861 atcaatatca acttattttg aaggaataag taaggcgagt tataaacaac tggttatagg
    25921 tatatgtgta gctagtatgc ttatatcaaa tttaggtgtt gattctataa tagctatatc
    25981 agttccaatc ctacaaacta tatatcctgt tttattagca atagttgtta tggagttggc
    26041 tggtaaacat ataaagaatg ataatgcttt taaaggtgca gcatatgtta cattagtgat
    26101 tagtctatta tcagctataa atggaatgac aggagctgtt ccatttatac aaagcttgcc
    26161 actcgcaggt ttgggcttta actgggtaat accagctata ttgggtggaa tagttggtaa
    26221 ctttataaaa agcaacaaac aagtagcata ataatttgta attaatttaa ttttataata
    26281 tattaatttt tagtactatg ggtaggttta atctaaacct aatctaccca tagtactttt
    26341 tagattggat tggaatagca tgtatataat tttttataat ataatttttc tttgaagtat
    26401 gataaaatta gtaatagtga taagaaagta caaatttagg aggttttaat taatgcttag
    26461 aaaaataaca gcatttatgc tatccatatg tttaattatt ggacttacag gttgtagttt
    26521 acttgtaggc aagaaagata aagagaaaat tatagatgat tttaaagttg cagtggtaac
    26581 tcaaccatta tctgaaaata aagtacaata caatatggtg gaagagatga caaaagaata
    26641 tgaggaagag aataaaattg ataaagacaa agatggtcaa actaaagtta aacaaactat
    26701 aaaacatgtt gtattgccag agaattttac ttctaatata gatagtgcta ttaataagat
    26761 agtaaagttg gctgacgata aagaagttca ggctattgta gtttcaactg accaagcagg
    26821 gcttttacct gctttacaaa aggtaaagga aaagcgtcca gaaataataa ctatttctgc
    26881 ccctatggga gatgataaaa accaattaag ccaatttgtt gatgtgaatc taggggttag
    26941 tgcagaggaa agaggaaaag tattagctga acgttcaaaa gaaatgggag caaaagcttt
    27001 tattcattat gcctctacag atgatttgaa agatgttaat atagccaaaa gattagaaat
    27061 gattaaagag acttgtaaaa atataggatt gccatttgta caagttaata ctccaaatat
    27121 aaatactgaa gaagacaaaa acaaagttaa gcagttttta aatgaagata ttgaaaaaca
    27181 agttaaaaaa tatggaaaag atataaatgt atttggtgta aatgagtata tggatgaagt
    27241 tatattgact aaggctttag aattaaagta tatagttgca gagcaaagca atccatcacc
    27301 aatacaaacg tatcctagtg ttatgggtct aaaaatatct gaaaaagatg ctcaaaatta
    27361 tgataaaata aacgacatga taagtgaaaa ggctaaggct tttggtatgt caaatagact
    27421 tggtggatat cctatgccaa tggatgcttt tctaccatca gtagcaattt atcttgctac
    27481 tgaaatggtg aaacaagatt taacacaaga agatgtatgt gacccagatt atttagaggc
    27541 gtttacagaa ttaagatttg gaatcggttc agaatttact cctttaacag aggtacttta
    27601 taattatcaa tcagtaattt taagccaatt aatttattaa tattaaggaa gtgtctcaaa
    27661 atgaactttt tagtttatga ggcactattt ttctgttaaa tcaaatatat ttttatcttt
    27721 ttaacaatta aaaagaagct tatccctatg ttgagatagc ttctttttta atataaataa
    27781 gttttattat tttat
//
LOCUS       DAMJYN010000051        27695 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.052, whole genome shotgun sequence.
ACCESSION   DAMJYN010000051 DAMJYN010000000
VERSION     DAMJYN010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 27695)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27695)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27695
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.052"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            73..146
                     /locus_tag="PC466_002337"
     tRNA            73..146
                     /locus_tag="PC466_002337"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:105..107,aa:Gly,seq:tcc)
     gene            155..271
                     /gene="rrf"
                     /locus_tag="PC466_002338"
     rRNA            155..271
                     /gene="rrf"
                     /locus_tag="PC466_002338"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            545..2563
                     /locus_tag="PC466_002339"
     CDS             545..2563
                     /locus_tag="PC466_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDF2769710.1"
                     /translation="MRRNTKLLTTGILSMAIVAPTMAFATESNAMENNADLNINLEKK
                     SIVLGSKSKVSVKFKEKPDADSITLKYKCYDMPLDTTLNYNQSTESYEGTINYNKDPE
                     YLNVWELQGITINSKNNPKTLNKQELEKMGLNLKDYNVTQECIIEDITSRKDVNKYLR
                     KTSAPITELTGSDRYETAVKISKEGWKNGSDKVVIINGDVSIDGIISTPLATTYNAPI
                     LLVEKNNVPNSVKSELKRLNPRDVIIIGDENAISKTTANQIKSTVNASQTRLKGSNRY
                     ETSLLIAKEIDKNHDVEKVYITNANGGEVDALTIAAKAGQDKQPIILTDKNSITDNTY
                     KWLKSEDLQNAYFIGGPQMISTNVINKVNDITKDNVTNNRVYGADRHETNANVIKKFY
                     TDDELEAVLVAKSDVLVDALAAGPLAANLKSPILITPKTYVSAYHKDNLEAKSANKVY
                     KIGGGLTSKVMNSIASSLSKHNTTPTEPGNSGGKTVMIDPGHGGSDTGTTGKPLGGIK
                     EKDYTLNTSLATTEYLRSKGFNVIMTRDTDKTLSLGNRTALSNSLRPDLFTSIHYNAS
                     DTTGNGVEVFYKLKDKDGGTTKTVATNILNRILEKFNLKNRGAKTRTLSTDPTKDYLY
                     VLRNNDMPAVLVECAFLDNEKDMSLLNTSNKVKEMGTQIGKGIEDSLK"
     gene            3076..5088
                     /locus_tag="PC466_002340"
     CDS             3076..5088
                     /locus_tag="PC466_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDF2769711.1"
                     /translation="MRRNTKLLTTGILSMAIVAPTMAFATESNAMENNADLNINLEKK
                     SIVLGSKSKVSVKFKEKPDADSITLKYKCYDMPLDTTLNYNQSTGAYEGTINYNQDPE
                     YLNVWELQGITINSKNNPKTLNGQDLEKMGLNLKDYNVTQECIIEDITSRKDVNKYLR
                     KTSAPITELTGSDRYETAVKISKEGWKNGSDKVVIINGDVSIDGIISTPLATTYNAPI
                     LLVEKNNVPNSVKSELKRLNPKDIIIIGDENAISKTTANQIKSTVNASQTRLNGSNRY
                     ETSLLIAKEIDKNHDVEKVYITNANGGEVDALTIAAKAGQDKQPIILTDKDSITDNTY
                     KWLKSEDLQNAYFIGGPQMISTNVINKVNGITKDSVTNNRVYGADRHETNANVIKKFY
                     TEDEIEAVLVAKSDVLVDALAAGPLAANLKSPILITPKTYVSAYHKDNLEAKSANKVY
                     KIGGGLTSKVMSSIASSLSKHNTTPTEPGNSGGKTVMIDPGHGGSAPGNSSGGMIEKD
                     YNLNTSLATTEYLRSKGFNVIMTRDTDKTLSLGNRTALSNSLKPDLFTSIHYNGSTNK
                     QGHGVEVFYKLKDKNGGTTKTVATNILNRILEKFKLTNRGIKTRVLPSDSTKDYLYVL
                     RSNDMPAVLVECAFLDNENDMSLINSSAKVKEMGTQIGKGIEDSLK"
     gene            5316..7229
                     /locus_tag="PC466_002341"
     CDS             5316..7229
                     /locus_tag="PC466_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769712.1"
                     /translation="MEYLFEKSSLKEYGNEALDKYRELLDKTDNNSRCILLLVPNNNT
                     KIRYERALRLNYSEELKITTYISFVKKELVKYWPLIIEKCDEINTKVVSPTFISNSLS
                     EYLIVQKVKEKRIQEGYFEDITGTNKSIANSIMTNINKSAFNLIDFDFIGEKIYSSKK
                     NKDSIYRFSYTQMDEIISYYINSLLSNSILDNALSIYLYNQYLLNDDFYLKNLFTEVR
                     YIIVDSLESSSNAEVDFITEALDNTLQSYIYFDYSRDYSVFNNVDIDYINEKIISKIK
                     PKEENIKKKEIRIEDLYLLPANIELNQSSQLYNEMLDLISEKVISLIEENVSPRDIAI
                     ISPINNSILEHQIRDSLIEKNIDVFSTKKDKKAVDYPYGNALVVATCIFYGYLDFIKD
                     DEYLSFLETLLEINRIKAFKIFNETRHLSIDNIDEHSQYRDILQYIEEKKKSDIKIHE
                     FLTQFYIDKMLNLKEGKKNVGLCKKIIAESESFSESLSLLRMKKEKIFIEALKSTIND
                     YYSVVDIEELKSKDKIVITTPYSYISSNIDRSIQIWVDIGSNAWNMKIEKDISNLIVL
                     RKSFEEKKIYTNEMEEYYKKYYLYNTVYNLLLNAKKIYAFKSEYAINGYIQESILYSI
                     LLKISHKGDKNYD"
     gene            7222..9441
                     /locus_tag="PC466_002342"
     CDS             7222..9441
                     /locus_tag="PC466_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HDF2769713.1"
                     /translation="MININYREDQIPIINYDNGTMAVPAVPGAGKTFIITNLVAKLLL
                     EQKHKGGKILILTYMNSAVNNFKGRIRKILEENKIDDTNSYEVMTIHSLAVKIIKEKP
                     EVVMLSEDFNIADDLQKSIILNECISRFRFEGGERAFRWFLKEQKDERWKEIALEAWE
                     RGFFEFAGNAISELKYKGISPDKLEEILSRGHKGMLKIILPIYKLYDRKLKQNGLLDY
                     DDILILAEKTLSLDEGLRKKFQTRYKYIFEDECQDSNEIQGNIIKIISSENKNLVRVG
                     DINQSITGTFSSSDPKFFKEFINSADFCYRMDMSNRSSKDILDLANTLVKYVTKEFRQ
                     EECRHALEDMQIKTVPNGMGYKENPNPEHYNINVKWYESWKIEIEQTARYVKGIKNKY
                     PDKSIGILVPFNEQVTQVAKELRENNLTFEELGPNSLNKRKVINNIAYIIDFMLHCDD
                     VEKLIVVLNKVFIDTDNEEEIKYFLEELKNYSTEEIIYNFEFSKLDNDLIEFKEESDI
                     YLSFKRGIDIIKQILEYPIIRLDLLVLFIGKKLNLEKEDKAVLDYISFYIKYLISENI
                     NMDLEDVYNLLFDVKNRVFNHIIDVVYEINGYEPEPGSITLCNYHKSKGMEWDCVFLL
                     GLVEYNFPDNINQKFQSDKWYLKEKYKNPMAIIKSEVEAILKGSISTDYAHKTKIDSI
                     NEKIRLLYVGITRAKEMLVLSGSAYRDESDIGNKRKEQKPCIYLSRLNQHIIEKRSN"
     gene            9550..10380
                     /locus_tag="PC466_002343"
     CDS             9550..10380
                     /locus_tag="PC466_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HDF2769714.1"
                     /translation="MNDKLKYFSYSQNSINTYKSCPLKFKYKYIDRINWKNDDVGSRE
                     YYETLKTGRDFHLICERYFSNIPLGIYFNEDDKNSKKFLKWMENIKKVVPIEKGKTYL
                     PEYEVRMTLNGDIIQAKYDLVVIGNNNIEIWDWKTESKKIDYKHVENRIQTIVYMFLA
                     KEVIPKVLKMDINVKDINMRYYQPEFDDLPITILYDEEKHEANRNKIQNYISMIKNTN
                     YEEHTYEDNLYNDIEKVYNKEERMCYRNKKHCKYCEFNKLCNGKEIDYSILEAEIYGT
                     "
     gene            10370..13837
                     /gene="addB"
                     /locus_tag="PC466_002344"
     CDS             10370..13837
                     /gene="addB"
                     /locus_tag="PC466_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddB"
                     /protein_id="HDF2769715.1"
                     /translation="MGLRFVLGRSGSGKSTYILDEIKKEAQKNETTSIILLVPEQYTF
                     EAENRVSKLFLGKEKDKYLRVRVLSFKTLSNIVFSQVGGLTDVNINSSGKAMMVYRAI
                     EDVSEELNVFSKSKSQSGFVSSITDMISEMKQYNISPEMLENISGELDNETLSLKLKD
                     ISKIYNSFEGKLHENYVDAQDMLTSLASKIELSSYLDGACVYIDEFTGFTPNQYNVIK
                     SILNKSKSVNISLTVDDINYIGYSKSDMFSRTKFTYSKLTQLCNEEGIKILPQVNLNT
                     GVIKRFEKVKELQHLERFYNAYPYKIYSNPTENIKIKEFNNLYSEVEEIAREIVHLVR
                     DKNVRYRDITIATRDLNRYDFLVHSIFNEYNIPNFIDKKREAKSNPIVILIISALEMK
                     NRRYGYETMFRYLKSGLIGIDNDDINLLENYVLANGIKGKKWFDEKWDYRITQSLSGQ
                     ESEFELELKEKINEIKNRVLEPIVILQEKLRGKNRVKEICRYIYEFLLDINMPETIEN
                     LIVNFKDKGELDVANQYSQVWDIVVDILDQMVELMGDEIISLEKFIKLITLGFDEYEL
                     GLVPPSIDQVLVSSVDRMKNPDTKYLYLVGTTDGVFPLITKDSGILSDNDRESLGNKG
                     IEVDIDSKTRSFEEQFLVYKALTSTSKNLTITYPISDHEGKTLRPSIIISRLKKIFPN
                     IENKSYLVEENKSTDKDILKKITVKSPTFNELINVIKNYDSDDYNTEEINSIWLDIYR
                     YYLKDEIYSSITKKVIKGLSYTNQVHKIEEKKIRSLYKSNSLSISRLEKYAECPFAYF
                     IQYGLKAKKRKEYSFTPPDLGTFIHNILDRFSKELLQDNLTWRDIDEKYIELKIGIIV
                     DEIILKIPGYILNSSERYKYLAYRLKNMLTTAITIISQQIKQGSFEPIDYEVKFGDNG
                     KYPPIKMVLENGQEVSLIGQIDRVDEFEEGENKYIRIIDYKSGNKSISLTEIYYGLQL
                     QLLVYLDAILESAKDEDININPAAILYCRINNPIAKFNEDKDDEEIQEAILKELRMKG
                     LVVKDSHIVKEMDKSLIDGERKNSLVIPVGLTKDGNVGKSTSAISYEDFKLLRKYVRH
                     AIKDLCEEMLSGEIRIAPYKHKDGTSCDFCDYSTICQFDSTIKDNKYKNLNNKSNEEI
                     IKMMKGDVN"
     gene            13837..17664
                     /gene="addA"
                     /locus_tag="PC466_002345"
     CDS             13837..17664
                     /gene="addA"
                     /locus_tag="PC466_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HDF2769716.1"
                     /translation="MSSPKWTKEQLEVIGSRECNLLVAAAAGSGKTAVLVERIIQMIT
                     SRENPIDIDKLLVVTFTNAAASEMRERIGDAIGKALDENPENKHLQNQLVLLNKSSIT
                     TIHSFCLDVIKSNFHRINLDPNFRIGDQTECAILKQEAIEEVFEDLYEERDEGFLNLV
                     ESYAERGGDKEVQDIILGIYSFAMASPEPKKWLIDSAERFNIDENFDFSQSIWARAIL
                     DTVKIEINGLCLNMERALKEVESIEELETFAEKLSVEYKKIANISQACNKSWDEAYKK
                     MASMSFENYVKGVKRISKDAPSYIKESKEKAKTIRDKTKKSLESIVSATFNKDNDSIR
                     EEIKYLYNIVKPISSVVLRFEEEYSNKKREKGIIDFNDIEHFALNILTDIDEKGNIVP
                     SDIAVGYRNKFYEIFIDEYQDSNLVQEVLLKAVANTETPNRFMVGDVKQSIYRFRQAK
                     PELFLQKYNNYNDKKGSSHRKIMLYKNFRSREEVVDAVNYIFENIMNENIGEIEYTEK
                     ERLNLGANFNVDTDEKSIIGGATEIHLIQKDNKLDDDIINDKDDRINNKENEIEEEEK
                     LDNIQLEARMVGNIIKDLMKVNEDGKIQKVYDKGIDGYRPVEFRDIVILLRATSAWAP
                     VFADELMNMDIPTYADVGVGYFDTIEIKTILSLLQIIDNPMQDIPLISVLKSPIFGFT
                     PEDLIDIRVQSKDKIFYEVLKSTAEYDGFTDSQNETESEFIPSEECINKSKDFLIKLK
                     EFKEKSMYMSTDEFIWYLYTRTGYYAYVGALPGGSQRQANLKVLFERAKQFEETSLKG
                     IFNFVNFIEKLKKSSSDMGSAKTLGENANVVRIMSIHKSKGLEFPVVICSAMGKNFNT
                     QDFKKSILYHHNLGYGPQFVDYERRISFPSIAKEALKSKINIENLSEEMRVLYVAFTR
                     AKEKLIITGSTRNIQDSIKRWSNGIESLDTISQYEILKGKNFLDWIMPCVLRHRDLSN
                     LLEEVGLDAVFNVEHNSKWYGKLWNKNDILVEKKSDEEKESIEEILEKIDVDSPDSDY
                     YSEIEKKLNYIYPYEFSTRKPATISVTEIKKIQNNYEEELINTIFEQKVILKKPLFIQ
                     NEEEREKISGTERGTIVHLVMEVLDLKNVSSVNDIKSQIRGFVSKGIITEKQASIVNP
                     YKIYKFFASNIGKRMLNAEIINREKSIYAQVNMKDIYIYEKLINNDDKKLYDNESVML
                     RGIVDAYFEEDNQIVLVDYKTDFVNEENINQIIEKYKKQLDLYADIIETLTGKSVKEK
                     CIYLFGVDEAVCY"
     gene            17710..18921
                     /locus_tag="PC466_002346"
     CDS             17710..18921
                     /locus_tag="PC466_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HDF2769717.1"
                     /translation="MRFIHTSDWHLGKSLEGHSRIEEQAKFCEEFIKIVESNEIDMVI
                     IAGDVYDTSNPPAQAEKLFYQTVSRLANNGQRCVLIISGNHDNPERLSAITPLAHEQG
                     ILIYGYPLSATIEAKYKGFEITYATQGCTKLNINGENIVIATLPYPSEKRLNEVFSSE
                     DEFEKQKNYSEKVGDIFRSLEENFRSDTINIAVSHIFVIGGESTESERPIQLGGSFLV
                     ERKDLPEKAQYTALGHLHKQQKASERLNAYYSGSPLQYSKDERAYTKGAYIVDIKAGE
                     KPIIEDVYFNNYKPIEVFKCNGIEEALDICEQNQDREIWSYFEINTDEIISQNEIKKM
                     KELLKDIIEIKPIITSCYEQESVDIKEKSMAELFREFYSFSKGVEPKGELMDLFLDII
                     SEEGESADETN"
     gene            18908..22435
                     /locus_tag="PC466_002347"
     CDS             18908..22435
                     /locus_tag="PC466_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF2769718.1"
                     /translation="MRPIRLELTGLNSYIDKQVIDFEKLIERGLFGIFGTTGSGKSTI
                     LDAITIAMYGNISRNTKEYINSVCDKAIISYEFEIGSKNTRRRYIVDRTIARSKTGTK
                     TSNARLIEVLNDNIQNVLADKVVEVNEKVAQVVGLTANDFTRSVVLPQDKFNEFLRLS
                     RADRRDMLERIFNLEKYGRSLGEKVKKRKNIQLQNLKDLKSKLSQYDGITEEVYNNIN
                     QELIELKNLEKDKNNALDLAQKSYEESKTVYEEQLKLEKNELRKNELDLKNSEIKEKI
                     ALVENDSNAKKVDPYISSVQNLEKKIDEDSFVVSNLEKKLAILNQELEVTKNRYEKIN
                     KIKNEEVPKLSEEKIRLQQAIKLEEELVLLDRELKDLKESGINLNKTKVELEKVKQVS
                     ESRKDAVTKSIKEVEGKIDKVNISAELKQKIFLAYEYEKDYNNVLEEKNQKLNKLEEI
                     LKETENINLKVRYIDKDKNDVNRNLENLSLHLDVLLKKCPGKSADLLLKSEYVTELRS
                     KANNTKENEIKKSSIQDELKIILESKFNTEREVNLLNEKLENNRKNRDDLEKELEELK
                     YLNLASELRRELKENMPCPVCGSKHHENHNITKYDENISFVKEKLEKLEKEKISIRNN
                     IEELNAKVSGYLSIEKMKTKELEDVKGKLGGIPSSQLLKKLDEEQRKLALLKSNIQEW
                     EKEKESTENKVTLAKEEKNKIEKEELKIRESLNNYKKLTRDLNIEIEGLENKCKKLKQ
                     EYLGLKTITKVSNLLSKVKEIRENEKELELLSTGHSNLLKNRDSLDIKIRENESKLHE
                     IEIELIKARELYVEKKLSRDNKYKEVINITKGDLAKNLLHNVEENICKILEQEESSKK
                     KLEEQRLEYEKNIAEKHNIDGRLKTAKEQYKDQKSTLNKLLAENKFESIYAVKRALLD
                     TDAVKKLIEEILEHEEEQKLLSFKIKSSKEKLNGRSIKKEYFEQLKDEIYNLKVEIGN
                     ISKDIGANQNQLITLKDSLDKINDFNKQLKVVEHNVDLLEELDKCVQGNKFVEYVSTN
                     QLKYIALEASKRLDGITKGRYALEIDSTLNFVMRDNFNGGERRSIDTLSGGETFLTSL
                     SLALALSSQIQLKGSAPLEFFFLDEGFGSLDSELLEIVIESLERLHSNNLSVGIISHV
                     EELKNRVPVKLLVSSSEAGIGSKVKIEYS"
     gene            22566..23819
                     /locus_tag="PC466_002348"
     CDS             22566..23819
                     /locus_tag="PC466_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HDF2769719.1"
                     /translation="MLESPNNLIQIIFLIVLLIGSAFFSASETALMSLSKIRIRYMQD
                     EGVKGAKLVSSLIENPNKLLSSILVGNNVVNIAATSISTSLFIGLMGEKGVALATAVM
                     TVLVLIFGEITPKTIAANNSEKVSLLVSKPIKAIIFILRPIVWIFNIITNIIFKLFGI
                     TNKGAKSFITEEELKTMVNVSHEEGVLEMEEREIINNVFEFGDMQAKNAMVQRIDMVA
                     IDMEDSYDEIIQVFKTEKLSRMPVYEETIDDIVGILNIKDIIFLSDEEIESFDIKNYM
                     REPFFTYEFKKITQLLEEMKLEKSQMAIVVDEYGGTSGLLTIEDLVEVIVGDIEDEYD
                     EEEDEIQVIKEDEYIVDGSTKIGDVNELIGVNLESEEFDSIGGFIIGHLSRLPEENEV
                     IEVDNIRFCIESIEKNRIKKIRIYT"
     gene            23968..25019
                     /gene="ytvI"
                     /locus_tag="PC466_002349"
                     /pseudo
     CDS             23968..25019
                     /gene="ytvI"
                     /locus_tag="PC466_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437952.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation integral membrane protein YtvI"
     gene            25110..26336
                     /gene="pepT"
                     /locus_tag="PC466_002350"
     CDS             25110..26336
                     /gene="pepT"
                     /locus_tag="PC466_002350"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HDF2769720.1"
                     /translation="MKQKVVERFLKYVSFDTTSNSQCENCPSSEGQRVLAKYIVEELK
                     TMGVDDVSLDENSYIMATLKGNTDGVDTIGFISHLDTIEDVSGKDIKPRIIENYDGKD
                     IVLNEALNVITYVKDSPELEEFKGDDLIVTDGTTLLGSDDKAGIAEIVTAIEYLINHP
                     EIKHGDIKIGFTPDEEIGRGADLFDVEKFGAKYAYTLDGGIVGELECENFNAANATIT
                     IHGRNVHPGSAKNKMVNAIHIAAEISEMFPADERPETTEGYEGFWHLNSIGGNVENVS
                     MAYIIRDHCREKFENRKSIMIENIEKINKKYDNRVELDLKDSYYNMKEKIEPVMFIVD
                     IAKEAMEELGIKPRLVPVRGGTDGARLSFNGLPCPNIFTGGLNFHGKNECIPVSSMEK
                     ATKLIVRIAEKYAERV"
     gene            26543..27595
                     /locus_tag="PC466_002351"
     CDS             26543..27595
                     /locus_tag="PC466_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp18"
                     /protein_id="HDF2769721.1"
                     /translation="MKIKSKKIIAFALSLGIMLPSCVYADTISKNQNAQVDMNNYLQG
                     RKSPKEEKLIGEDRFDTAIKISQSGWNNGSERVFLVNSNSLPDALASTPLASKLDAPI
                     LLTNKNSIPYNVTEEIKRLNPAEVILIGSEGAISSSVKESLEDMEVLVSRIGGADREE
                     TSLLLTRQLDDTGDLGVSKVAVVNGYNGLADATSISSPAASDNTAIIYTGKDSIRSEA
                     KNFITQNSTKTYIVGGEYSISKKLEGQLVNSERLAGTDRKDTNAKVLEKFYGKSSKVN
                     NMYFAKDGSGREADLVDGLAAGVLASKTKSPVVLASGSLSSAQKSFIKKVKADKFVQV
                     GGGKNSKPYAEALALQ"
BASE COUNT        11741 a         2720 c         4906 g         8328 t
ORIGIN      
        1 attaggatat atatgtagtt tttagggtgc taactctaaa aaattagttt tactaattta
       61 taaaaattta atgcgggtgt agctcaatgg tagagttctg gccttccaag ccagctgtga
      121 gggttcgatc cccttcaccc gctccaaaag attatgtggt tacaatagca gagaggatac
      181 acctgttccc attccgaaca cagaagttaa gctctctagt gctgatggta cttggtggga
      241 aactgcctgg gagagtagga cgtagccacg taatcttttt ttgttgtatt aaatttaata
      301 aacctacaat tgttatatgt ttttatttgt cttttataga tttttttggc aataaatgat
      361 atagtgaaga taattaaata tattcaatat atttaatttt tttatttttt gtttttataa
      421 tttttttaga agtttatttt ttatgtaatt atttataatt ttgggtaaaa acactttgat
      481 ataatttcaa aaattaaaag gttaaaaaac aaagtagaaa tttatgttaa ataaggagat
      541 taatatgaga agaaatacaa aattattaac aacagggatt ctttcaatgg caatcgtcgc
      601 acctacaatg gcatttgcta ctgaatctaa tgctatggaa aataacgctg atttaaatat
      661 aaacttagag aaaaaaagta tcgttttagg tagcaaatca aaagtcagtg tcaagtttaa
      721 agaaaaacca gatgcagata gcattacatt aaagtataaa tgctatgata tgccattgga
      781 tacaactcta aattataatc aatcaactga gtcatatgaa ggaactatca attataataa
      841 agacccagaa tatttaaatg tttgggaact acaagggata acaataaaca gcaaaaataa
      901 tcctaaaact ttaaacaaac aagaactaga aaagatggga ttaaatttaa aagactataa
      961 tgtaacgcag gaatgtataa ttgaagatat aacttctaga aaagatgtaa ataaatattt
     1021 aagaaaaact tctgcaccta ttacagaact tacaggaagt gatagatacg aaacagcagt
     1081 taaaataagt aaagaaggct ggaaaaatgg ttcagataag gtagttataa taaatgggga
     1141 tgtaagtata gatggcatta tatcaactcc actagcaact acatataatg ctccaatact
     1201 tttggttgaa aaaaataatg tacctaatag tgtaaaatca gaattaaagc gtttaaatcc
     1261 tagagatgta attataattg gagatgagaa tgctatttct aaaactactg ctaatcaaat
     1321 taaatcgact gtaaatgcta gtcaaacacg tctaaagggc tctaatagat atgagacatc
     1381 tttattgata gcaaaggaaa tagataaaaa tcatgatgtg gaaaaagtat acataacaaa
     1441 tgctaatggc ggagaagtgg atgcacttac tatagcagca aaagcaggtc aagacaagca
     1501 accaattata ttaactgata aaaatagtat tacagacaac acatataaat ggttaaagag
     1561 tgaggattta caaaatgctt attttatagg tggacctcaa atgatatcaa caaatgttat
     1621 aaataaggta aatgatataa ctaaagataa tgttactaat aatagagtat atggagcaga
     1681 tagacacgaa acaaatgcaa acgtaataaa aaaattctat acagatgatg agttagaggc
     1741 tgttttagta gctaaatcag atgtacttgt tgatgcttta gcagcaggtc cattggctgc
     1801 gaacttaaaa tctccaatac ttataacacc aaagacgtat gtatctgcat accataaaga
     1861 taatttagaa gctaaatcag ctaataaagt atataaaata ggaggaggat tgacttctaa
     1921 ggtaatgaac tctatagcat catcattatc taaacacaat acaactccaa cagaaccagg
     1981 aaatagtggg ggtaagacag ttatgattga cccaggacat ggtggttcgg acactggaac
     2041 aacaggtaaa ccattagggg gtattaaaga aaaagactat acattaaata cttcacttgc
     2101 gacaactgaa tatttacgtt caaagggatt caatgtaata atgacaagag acacagataa
     2161 gactttatct cttggaaata gaactgcttt atctaactct ttgagaccag atttatttac
     2221 gagtatacac tataatgcat ctgatacaac tgggaatggt gtagaagtat tttataagct
     2281 taaagataaa gatggaggga ctactaaaac tgtagctaca aatatattaa atagaatctt
     2341 agagaaattt aatctaaaaa atagaggtgc aaaaacaaga acactatcaa ctgaccctac
     2401 aaaagattat ttatatgttt taagaaataa tgatatgcca gctgtacttg tagaatgtgc
     2461 atttttggat aatgagaaag atatgagttt acttaataca tcaaataaag taaaagaaat
     2521 gggtacacaa ataggtaaag gcatagaaga ttcattaaaa tagtctacaa tgagagcata
     2581 gaaaaattta aaataaatta atctgcaatt ttaaatttaa actaaagcta taagataaga
     2641 atgtaattat aatagtaata aagactgtat atacattgtg catataagtg cgaaatgagg
     2701 tatatacagt ctttttatga ttaattgtaa aaggatttat attatatgaa gaatttacat
     2761 atcttaaggc tacagttaat tgtcaagagt tggagtattc atttgtaata cacaataaaa
     2821 gcttaattac tatattttat tgtgtgtttg tgtgtttgtg tgttttttgt ggatttttat
     2881 gtcaataaat gatatagtat agataattaa atgtattaaa tatatttaat ttttttattt
     2941 tttgagtttt ataagtttat ttttatatat tacttatata ttatttatat tttgggttag
     3001 atacactttg acatattttc aaaagttaaa agattaaaaa taaagtagaa atttatgtta
     3061 agtaaggaga ttaatatgag aagaaataca aaattattaa caacagggat tctttcaatg
     3121 gcaatcgtcg cacctacaat ggcatttgct actgaatcta atgctatgga aaataacgct
     3181 gatttaaata taaacttaga gaaaaaaagt atcgttttag gtagcaaatc aaaagttagt
     3241 gtcaaattta aagaaaaacc agatgcagat agcattacat taaagtataa atgctatgac
     3301 atgccattgg atacaactct aaattacaat caatcaactg gggcatatga aggaactatc
     3361 aattataacc aagacccaga atatctaaat gtttgggaac tacaagggat aacaataaac
     3421 agcaaaaata atcctaaaac tttaaacgga caagacctag aaaagatggg attaaattta
     3481 aaagactata atgtaacaca ggaatgtata attgaagaca taacttctag aaaagatgta
     3541 aataaatatt tgagaaaaac ttctgcacct attacagaac ttacaggaag tgatagatat
     3601 gaaacagcag ttaaaataag taaagagggc tggaaaaatg gttcagataa agtagttata
     3661 ataaatggag atgtaagtat agatggcatt atatcaactc cgctggcaac cacatataat
     3721 gctccaatac ttttggttga aaaaaacaat gtgcctaata gtgtaaaatc agaattaaag
     3781 cgcctaaacc ctaaagatat aattataatt ggagatgaga atgctatttc taaaactact
     3841 gctaatcaaa ttaaatcgac tgtaaatgct agtcaaacac gtttaaatgg ttctaataga
     3901 tatgagacat ctttattgat agcaaaggaa atagataaaa atcatgatgt ggaaaaagta
     3961 tacataacaa atgctaatgg cggagaagtg gatgcactta ctatagcagc aaaagcaggt
     4021 caagacaagc aaccaattat attaactgat aaagatagta ttacagacaa tacatataaa
     4081 tggttaaaga gtgaggattt acaaaatgct tattttatag gtggtcctca aatgatatca
     4141 acaaatgtta taaataaggt aaatggaata actaaggata gtgttactaa taatagagta
     4201 tacggagcag atagacacga aacaaatgca aatgtaataa aaaaattcta tacagaggat
     4261 gagatagagg ctgttttagt agctaaatca gatgtacttg ttgatgcttt agcagcaggt
     4321 ccattggctg cgaacttaaa atctccaata cttataacac caaagacgta tgtatctgca
     4381 taccataaag ataatttaga agctaaatca gctaataaag tatacaaaat aggtggagga
     4441 ttgacttcta aggtaatgag ctctatagca tcatcattat ctaaacacaa tacgactcca
     4501 acagaaccag gaaatagtgg gggcaagaca gttatgattg acccagggca tggtggttca
     4561 gcacctggaa attcatctgg aggaatgatt gaaaaagatt acaatttaaa tacttcactt
     4621 gcaacaactg aatatttacg ttcaaaggga ttcaatgtaa taatgacaag agacacagat
     4681 aagactttat ctcttggaaa tagaactgct ctatctaatt cattgaaacc agatttattt
     4741 acaagtatac attataatgg ctcaactaat aaacaaggtc atggtgtaga agtattttat
     4801 aagcttaaag ataaaaatgg ggggactact aaaactgtag ctaccaatat attaaataga
     4861 attttagaga aatttaaact tacaaataga ggtataaaaa caagagtact tcctagtgat
     4921 tctacaaaag attatttata cgttttaaga agtaatgata tgccagctgt acttgtagaa
     4981 tgtgcatttt tggataatga aaatgatatg agtttaataa actcatctgc aaaagtaaaa
     5041 gaaatgggta cacaaatagg taaaggaata gaagattcat taaaataaat ggaaataaaa
     5101 atatttaaaa acttaatgta aatttatact aaagtcaaaa aatgaaatat aagtgtatca
     5161 atagtaagac tgtatgtaca tttgcacatg tgaatgcaag tatatataca gtcttttttt
     5221 gtagttaaat gcaataattt gattgtgttt tgtaaaatac acaatatgat ataattagat
     5281 aatatacact taatttaatt gaggaaggtg attatatgga atatttattt gaaaaaagta
     5341 gtttaaaaga atatggaaat gaagctttag ataaatatag agaattatta gataaaactg
     5401 ataataattc aaggtgtatt cttttattag taccaaacaa taacacaaag atacgatatg
     5461 aaagggctct aagattaaat tatagtgaag aactgaaaat aacaacatat ataagttttg
     5521 tgaagaaaga attagttaaa tactggccac taataataga aaaatgtgat gaaataaata
     5581 caaaggttgt atctccaaca tttatatcaa atagtttaag tgaatattta atagtgcaaa
     5641 aagttaagga aaaaaggata caagaaggat attttgaaga tattacagga accaataaat
     5701 ccatagcaaa tagtataatg actaacataa ataaatctgc atttaattta attgattttg
     5761 attttattgg agaaaaaata tattcatcaa agaaaaataa agatagtata tatagatttt
     5821 catacactca gatggatgaa attatatcat attatataaa ttcgttacta tcaaattcaa
     5881 ttttagataa tgcattaagc atatatttat acaatcaata cctacttaat gatgattttt
     5941 atttaaaaaa cttatttaca gaagtgagat atataattgt ggatagtctt gaaagctcaa
     6001 gtaatgcaga agttgatttt ataacagaag cattggataa tacattacaa agttatatat
     6061 attttgatta tagtagggat tattctgtat ttaataatgt ggatatagac tatataaatg
     6121 agaaaataat atcaaaaatt aagcctaaag aagaaaatat taaaaagaag gagattagaa
     6181 tagaagattt atacttatta cctgcaaata tagaattaaa tcaatcaagt caattataca
     6241 atgaaatgtt agatttaata agtgaaaaag ttatatctct tatagaagaa aatgtatctc
     6301 caagagatat agcaattata tctcctataa acaatagtat attggagcat caaattagag
     6361 attctttgat agaaaaaaat atagatgttt ttagtactaa gaaggataaa aaagctgtag
     6421 attatccata tgggaatgca ttggtagtgg ctacatgtat attttatgga tatttagatt
     6481 ttataaaaga tgatgaatac ttaagctttt tagaaactct tttagaaata aataggataa
     6541 aagcatttaa gatttttaat gaaacaagac atttaagtat tgataatata gatgaacata
     6601 gtcagtatcg tgatatttta cagtatattg aagaaaaaaa gaagagtgat ataaaaatac
     6661 atgaattttt aactcaattt tacatagata aaatgttaaa tttaaaagaa ggtaaaaaga
     6721 atgttgggtt atgtaaaaag ataatagctg aaagtgagtc ttttagtgaa agtttaagtc
     6781 tacttaggat gaaaaaagaa aagatattta tagaagcttt aaaaagtaca ataaacgatt
     6841 attactctgt tgtcgatata gaagagttga aatccaaaga caaaatagta ataactactc
     6901 cttattcata tatatcatca aatatagata gaagtataca aatatgggta gatataggaa
     6961 gtaatgcttg gaatatgaaa atagaaaaag atataagtaa tttaattgta cttagaaaat
     7021 cttttgaaga aaaaaagatt tatacaaatg aaatggaaga atattataaa aaatattatc
     7081 tatacaatac agtatataat ttgttattaa atgcaaagaa aatctatgca tttaaaagtg
     7141 aatatgcgat taatggttat atccaagaga gtatattata tagtatactt ttaaaaatct
     7201 cacataaagg agataaaaat tatgattaat ataaattata gagaagacca gataccaata
     7261 ataaattacg ataatggtac tatggcagta ccagcagtac caggtgctgg aaaaacattt
     7321 ataataacaa atttagtagc taaactatta cttgaacaga aacataaggg tggtaaaata
     7381 ttaattctta catatatgaa tagtgctgta aataatttta aaggtagaat aagaaagatt
     7441 cttgaagaga ataaaataga tgatactaat tcgtatgaag taatgactat acacagtttg
     7501 gctgtaaaaa taataaagga aaagccagaa gttgtaatgt taagtgagga ttttaacata
     7561 gctgacgatt tgcaaaaaag tattatatta aatgaatgta taagtagatt tagatttgaa
     7621 ggtggagaaa gagcttttag atggttttta aaggagcaaa aagatgaacg ctggaaagaa
     7681 atagctcttg aagcctggga aagaggtttt tttgaatttg caggaaatgc aataagtgaa
     7741 cttaagtata agggaatttc tccagataaa cttgaagaaa tattgtcaag aggacacaaa
     7801 ggaatgctta aaattatttt accaatatat aaattgtatg atagaaaatt aaagcaaaat
     7861 ggattgctag attatgatga tatattaatt ttagcagaaa aaactttaag cttagacgaa
     7921 gggcttagaa agaagtttca aactagatac aaatatatat ttgaagatga gtgtcaggac
     7981 tcaaatgaaa ttcaaggtaa tataataaaa attatatcta gtgaaaataa aaacctagtt
     8041 agagttggag atataaatca gagtataaca ggaacatttt catcatcaga ccctaaattt
     8101 tttaaagaat ttataaatag tgcagatttc tgttatagga tggatatgtc aaatcgaagt
     8161 tcaaaagata tacttgattt agcaaacact cttgtcaagt atgttacaaa ggaatttaga
     8221 caagaagaat gtagacatgc tcttgaagat atgcaaataa aaactgtgcc aaatggaatg
     8281 ggatataaag aaaatcctaa tccagaacat tataatataa atgtaaagtg gtatgagagt
     8341 tggaaaattg aaatagagca aactgctaga tacgttaagg gtataaaaaa taaatatcca
     8401 gataaaagta taggtatatt ggttccattt aatgaacaag tgacacaagt tgctaaagaa
     8461 cttagagaga ataatctaac ctttgaagaa ttaggaccaa attctttgaa taaaaggaag
     8521 gttataaaca acatagcata tattattgat tttatgttac attgtgatga tgtagaaaag
     8581 ttaatagttg tacttaataa agtttttata gatactgata atgaagaaga aataaagtat
     8641 tttttagaag aattaaaaaa ctattctacc gaagaaatta tttataattt tgaatttagt
     8701 aagttagata atgatttaat agaatttaaa gaagaaagtg acatatattt aagttttaaa
     8761 agaggaatag atattataaa acagatatta gaatatccaa taataaggtt agacctctta
     8821 gttttgttta ttgggaaaaa acttaattta gaaaaagaag ataaagctgt actggattat
     8881 atatcttttt atataaagta tctaatatca gaaaatataa atatggattt agaagatgta
     8941 tataatttat tgtttgatgt aaagaatagg gtgtttaatc atataataga tgtggtatat
     9001 gagataaatg gatatgaacc agagcccggt agtataacac tatgtaacta tcataagtca
     9061 aaggggatgg aatgggattg tgtgttttta ctaggtcttg ttgaatataa tttccctgac
     9121 aatattaatc aaaagtttca gagtgataaa tggtatctaa aagaaaaata taaaaaccct
     9181 atggcaatta ttaaatcaga agttgaagct atattaaaag gaagtatttc aacagattat
     9241 gctcataaaa cgaagattga ttctataaat gaaaagatta gacttttata tgtagggatt
     9301 actagagcaa aggaaatgtt agtactttca ggaagtgctt atagagatga aagtgatata
     9361 gggaataaga gaaaagagca aaaaccatgt atatatttaa gcagacttaa tcaacatatt
     9421 attgaaaaaa ggtcaaatta atatataata agttattaaa agattgcttg aaatatatct
     9481 aaaaggggat aaaacaatat gtacagtaag taactactaa aaaataaagt taagagagaa
     9541 gtgatatgag tgaacgataa attaaaatat ttttcttata gtcaaaattc aatcaacaca
     9601 tataaatcat gtccattgaa atttaaatat aaatatattg atagaataaa ttggaaaaat
     9661 gatgatgttg gtagtagaga gtattatgaa actttaaaaa caggaagaga ttttcatttg
     9721 atttgtgaaa gatattttag caatatacct cttggaatct attttaatga ggatgataaa
     9781 aatagtaaaa agtttttaaa gtggatggaa aatataaaaa aagttgttcc tattgaaaaa
     9841 ggaaaaacgt atttgccaga atatgaagta aggatgacct taaatgggga tataatacag
     9901 gcaaagtatg atttagttgt aattggaaat aacaatatag aaatatggga ttggaaaacc
     9961 gagtctaaaa agattgacta taaacacgta gaaaatagaa tacaaactat tgtttatatg
    10021 tttttagcaa aagaagtaat acctaaagtt ttaaaaatgg acataaatgt taaagatata
    10081 aatatgagat attatcaacc tgaatttgat gacttaccaa ttaccatttt atatgatgaa
    10141 gaaaaacatg aagcaaatag aaataaaatt caaaattata taagtatgat aaaaaacact
    10201 aattatgaag aacatacata cgaagacaat ctatacaatg atatagaaaa ggtatataat
    10261 aaagaagaac gtatgtgcta tagaaataaa aagcattgca agtattgtga atttaataag
    10321 ttatgtaatg gcaaagaaat agattatagt attttggagg cggaaattta tgggacttag
    10381 gtttgtatta ggtagaagtg gaagtggaaa atccacctat atactagatg agattaaaaa
    10441 agaagctcaa aaaaatgaaa cgacatcaat tatactttta gttccagaac agtacacatt
    10501 tgaggctgaa aatagagtaa gtaagctatt cttaggaaaa gaaaaagata agtatctaag
    10561 agttagggta cttagcttta agacactaag taatatagtt ttttctcaag taggaggatt
    10621 gacagatgta aatataaatt ctagtggaaa agcaatgatg gtatatagag ctattgaaga
    10681 tgtaagtgaa gaattaaatg tgttttcaaa atcaaaatcg cagtctggtt ttgtaagctc
    10741 aattacagat atgatatcag aaatgaaaca atacaatata agccctgaaa tgttagaaaa
    10801 tatatctgga gaattggata atgaaacttt aagtttaaaa ttaaaagata taagtaaaat
    10861 atataattct tttgaaggga aattgcatga aaattatgta gatgctcaag atatgttaac
    10921 ttcattggca agtaaaattg aattaagcag ttatttagat ggagcttgtg tttatataga
    10981 tgaatttaca ggttttacac caaatcagta caatgtcata aagagtatat taaataagtc
    11041 taaaagtgtt aatatctctt tgactgtaga tgatatcaac tatattgggt acagtaaatc
    11101 tgatatgttt tctagaacga aatttactta ttcaaaattg actcaattgt gcaacgaaga
    11161 aggcataaaa atattgccac aagtaaattt aaacacaggt gttataaaaa gatttgaaaa
    11221 agttaaggaa ttacagcacc tagaaagatt ttataatgct tatccatata aaatatattc
    11281 aaatccaact gaaaatataa agataaaaga gtttaacaat ttatattcag aggtggaaga
    11341 gatagccaga gaaattgtac atttagttag agataagaat gtaagatata gagatataac
    11401 cattgctaca agagatttaa atagatatga ttttttagta cactctatat ttaatgaata
    11461 taatatacca aactttatag ataagaagag agaggcaaaa agtaatccaa tagttatttt
    11521 aattatttca gctttagaaa tgaagaatag acgatatggg tatgaaacta tgtttaggta
    11581 tttaaaaagt ggacttatag gaattgataa tgatgatata aatttactag aaaattatgt
    11641 gttggctaat gggattaaag gtaaaaaatg gtttgatgaa aaatgggatt atagaataac
    11701 acaaagtctt tcaggtcaag aaagtgaatt tgaactggaa ttaaaagaaa aaataaatga
    11761 aataaaaaat agagtattag agcctatagt aattttacaa gaaaaattaa gaggaaaaaa
    11821 tagagtaaaa gaaatctgta gatatatata tgaattttta ttagatataa atatgccaga
    11881 aactatagaa aatttaatag taaattttaa ggataaaggg gaacttgatg ttgcaaatca
    11941 atactcacaa gtttgggaca tagtagtgga catattagac caaatggtgg aacttatggg
    12001 tgatgaaata atttctttag aaaaatttat aaaattaata accttaggct ttgatgaata
    12061 tgaattagga ctggttcctc ctagtataga ccaggtactt gtaagtagtg tggatagaat
    12121 gaaaaatcca gacacgaaat atttatacct agttggaact actgatggtg tgtttccact
    12181 gattacaaag gatagtggaa tattgagtga taatgatagg gaaagtcttg gaaacaaagg
    12241 aatcgaagtt gatattgata gtaagactag gagttttgaa gaacagtttc ttgtatataa
    12301 agctcttact tcgacatcta agaatttaac cataacatat ccaatatcag accatgaagg
    12361 taaaacgctt agaccatcaa taattatatc aagacttaag aagatatttc caaatataga
    12421 aaataaaagt tatttagtgg aagaaaataa aagcactgat aaagatatac ttaaaaaaat
    12481 aacggttaaa tcccctacat ttaatgaact tataaacgta ataaaaaatt atgacagtga
    12541 tgattacaat acagaagaga ttaatagtat ttggttagat atatataggt actatttaaa
    12601 agatgaaatc tatagttcta taacaaaaaa agttataaaa ggtcttagtt atactaatca
    12661 agttcataag attgaagaga aaaaaataag gtcattgtat aaaagtaatt ctcttagcat
    12721 atctaggctt gaaaaatatg ctgaatgtcc atttgcttat tttatacaat atggtctaaa
    12781 agcaaaaaag cgtaaagagt attcatttac accaccagat ttaggaactt ttattcataa
    12841 tattttagat aggttttcaa aagaactttt acaagataat ttaacttgga gagatattga
    12901 tgaaaaatat atagaattaa agataggtat aatagttgat gaaataattt taaagatacc
    12961 aggatatata ttaaatagtt ctgagaggta taaatacctt gcatatagat taaagaatat
    13021 gttgacaact gctataacta taattagtca gcaaataaaa caaggttcat ttgaaccaat
    13081 agattatgaa gttaaatttg gcgacaatgg aaaatatcca cctataaaaa tggtgttaga
    13141 aaatggacaa gaagtaagtt taattggaca aatagataga gttgatgaat ttgaagaagg
    13201 agaaaataaa tatataagaa taatagatta taagtcaggc aataagtcca taagtctaac
    13261 agaaatatat tatggtctac aattacaatt acttgtgtat ttagatgcaa tccttgaaag
    13321 tgcaaaggat gaagatataa atataaatcc agctgcaata ctatattgta gaataaataa
    13381 tccaatagca aaatttaatg aagataaaga tgatgaagaa atacaagaag caatattaaa
    13441 agaacttaga atgaaggggc ttgtagtaaa agactctcac atagttaaag agatggataa
    13501 atcattaata gatggagaaa ggaaaaactc tttagtaata ccagtaggtc ttactaagga
    13561 tggaaatgta ggtaaaagta cttcagcaat aagctatgag gatttcaaac tgcttagaaa
    13621 atatgtaagg catgctataa aggatttatg tgaagaaatg ttaagtggag aaatacgtat
    13681 agctccatat aaacataaag atggaacatc atgtgacttt tgtgattact ctactatatg
    13741 tcagtttgat tcaactataa aagataacaa gtataaaaat ttaaataata agagtaatga
    13801 agagataata aaaatgatga aaggagatgt taattagtga gttctcctaa atggacaaaa
    13861 gagcaattag aagttatagg aagtagagaa tgcaatttat tggttgctgc tgctgctggt
    13921 tcaggaaaaa cagccgttct agttgagcgt ataattcaaa tgataacaag tagagaaaat
    13981 ccaattgata tagataagtt attagttgtt acatttacta atgctgctgc gtcagaaatg
    14041 agagagagga taggggatgc tataggaaaa gccttagatg aaaacccaga aaataaacat
    14101 ttacaaaacc aacttgtttt attaaataaa tctagtatta caacaataca ctcattctgt
    14161 ttggatgtta taaaatcaaa ctttcataga ataaacttag accctaattt cagaatagga
    14221 gaccaaactg aatgtgctat tttgaaacaa gaagcaatag aggaagtatt tgaagattta
    14281 tatgaagaaa gagatgaggg gtttttaaat ttagttgaaa gttatgcaga aagaggagga
    14341 gataaagaag tacaagatat tatcttggga atatattcat ttgcaatggc ttctcctgaa
    14401 cctaaaaaat ggttgattga ctcagcagaa cgatttaata ttgatgaaaa ttttgatttt
    14461 tcacagtcta tttgggctag agctatatta gacactgtaa aaatagaaat taatggtctt
    14521 tgtctaaata tggaaagggc attaaaagaa gtggaatcaa tagaagaatt agaaactttt
    14581 gcagaaaagt tatccgttga atataaaaaa attgctaaca tttcacaagc atgtaataaa
    14641 tcttgggatg aggcatataa aaagatggca agtatgtcct ttgaaaatta tgtaaaagga
    14701 gtaaaaagaa tttcaaaaga tgctccttcg tatataaaag aatcaaaaga aaaggcaaaa
    14761 actataagag ataagactaa gaagtcttta gaaagtatag taagtgctac attcaataaa
    14821 gataatgatt ctattagaga agaaataaaa tatctttata acatagttaa accaatatct
    14881 agtgttgtac tgagatttga agaggaatat agcaataaga aaagagaaaa aggaataata
    14941 gattttaacg atatagagca ttttgcatta aatatactta cagatataga tgaaaaaggt
    15001 aatattgtac cttctgatat agccgttgga tatagaaaca agttttatga aatatttata
    15061 gatgaatatc aggatagtaa tctagtgcag gaagtactgc ttaaagctgt tgcaaataca
    15121 gaaactccaa atagatttat ggttggtgat gtaaaacaga gtatatatag atttagacaa
    15181 gcaaagccag aattattttt gcaaaaatat aataactata atgataaaaa gggaagttcc
    15241 catagaaaaa taatgcttta caaaaatttt agaagtagag aagaagttgt agatgctgta
    15301 aattatatat ttgaaaatat aatgaatgag aatataggag aaattgaata tacagaaaaa
    15361 gaaagactaa atttaggtgc gaattttaat gtggatacag acgagaaatc tattattggt
    15421 ggagcaacgg agatacacct aatacaaaaa gataataaac ttgatgatga tattataaat
    15481 gataaagacg atagaattaa taacaaagaa aatgaaatag aggaagaaga aaaattagat
    15541 aatatacaac ttgaggctag aatggttgga aacattatca aagatttaat gaaagtcaat
    15601 gaagatggaa aaattcaaaa ggtctatgat aagggaatag atggatatag acctgtggaa
    15661 tttagagata tagttattct tttaagagct acatctgcat gggctccagt gtttgcagat
    15721 gaattgatga atatggatat accaacatat gctgatgttg gagtggggta ttttgatacg
    15781 attgaaataa aaacaatatt gtcattactt caaataatag ataatccaat gcaagatata
    15841 cctcttatat ctgtattaaa atcacctata tttggattta caccagagga tttgattgat
    15901 attagagttc agagtaaaga taaaattttt tatgaggttt taaaaagtac agcagagtat
    15961 gatggattta cagattctca aaatgaaact gagtctgagt ttataccaag tgaagagtgc
    16021 ataaacaaaa gtaaagattt tttaattaag ctaaaggaat ttaaagaaaa gtcaatgtac
    16081 atgagtacag atgaatttat atggtacttg tacacaagga ctggatacta tgcttatgtt
    16141 ggagcattgc caggtggaag tcaaagacaa gctaatttaa aagtattgtt tgagagagca
    16201 aaacaatttg aagaaaccag tcttaaagga atattcaact ttgtaaattt tatagagaaa
    16261 ttaaaaaaat ctagttctga tatgggaagt gcaaaaacac ttggtgagaa tgcaaatgtt
    16321 gttagaataa tgagtattca taaaagtaaa ggtctagaat ttccagtagt catatgctct
    16381 gcaatgggta aaaatttcaa tactcaagat tttaaaaaga gtattttata tcatcataat
    16441 ttagggtatg gacctcaatt tgtagactat gagagaagga tttcttttcc aagtatagcc
    16501 aaagaagcat taaaaagcaa aataaatata gaaaatttat cagaagagat gagagtttta
    16561 tatgttgcat ttacaagagc taaagaaaaa ttgattataa ctggttctac tagaaatata
    16621 caagatagta taaagagatg gtcaaatgga attgaaagtt tagatacaat atcacaatac
    16681 gagatattaa aaggtaaaaa ttttttagat tggataatgc cttgtgtatt aagacatagg
    16741 gatttatcta atctactaga agaagtagga ttagacgcag tttttaatgt tgaacataat
    16801 tcaaaatggt atggaaagtt gtggaataag aatgatattt tagtggaaaa gaagagtgat
    16861 gaagaaaaag aaagtattga agaaattctt gaaaaaatag atgtagatag tccggacagt
    16921 gattattaca gtgaaataga aaaaaaatta aactatatat atccatatga atttagtaca
    16981 agaaaacctg ctactatatc tgttacagaa ataaaaaaga tacaaaataa ttatgaagaa
    17041 gagttaataa atactatatt tgaacaaaaa gtaatattaa aaaagcctct atttattcaa
    17101 aatgaagaag aaagagaaaa aataagtgga acagaaagag gtacaatagt ccatttggtt
    17161 atggaggttt tagacttaaa aaatgtaagt agtgtaaatg atataaaatc acaaataaga
    17221 ggttttgttt caaaaggtat aataacagaa aaacaagcta gtatagtaaa tccatataaa
    17281 atatataaat tttttgcctc taacatagga aaaagaatgt tgaatgctga aattataaat
    17341 agagaaaaat caatttatgc acaagtaaat atgaaagaca tatatattta tgaaaagctt
    17401 ataaacaatg atgataaaaa actttatgat aatgaaagtg tcatgttaag aggtatagtt
    17461 gatgcttatt ttgaagaaga taatcaaata gttttggtgg attataaaac agattttgta
    17521 aatgaggaaa atataaatca aataatagag aaatataaaa aacagttgga tttatatgca
    17581 gatattattg aaactttaac tggtaagtca gtaaaagaga aatgtatata tttatttgga
    17641 gttgatgaag ctgtttgtta ttagttttta tatataaatt aaacctaaaa gatagaggaa
    17701 ggggaaaaaa tgagatttat tcatacatca gattggcatc tagggaagtc cctagaaggc
    17761 cattctagaa ttgaggaaca agcaaagttt tgtgaggaat ttataaaaat agtagaatca
    17821 aatgaaatag atatggttat aattgctgga gatgtatatg atacttctaa tcccccagca
    17881 caagcagaaa aactatttta tcagactgta tcaagacttg ccaataatgg tcagaggtgt
    17941 gtattaataa tttcaggaaa tcatgataat ccagagagac tttctgcaat aacacctcta
    18001 gcacatgaac aggggatact tatatatggt tatccattaa gtgctacgat agaagctaag
    18061 tataaagggt ttgaaataac atatgcaact cagggatgta caaaactgaa tataaatgga
    18121 gaaaatattg tgattgctac attaccttat ccaagtgaaa aaagattaaa tgaagttttt
    18181 tcaagtgaag atgagtttga gaaacaaaaa aattattctg aaaaggtagg agatatattt
    18241 agaagtttag aagaaaattt tagaagtgat actataaata tagccgtatc acatatattt
    18301 gtaataggtg gagagagtac tgaatcagaa agacctatac aattaggtgg aagtttttta
    18361 gttgaaagaa aagatttgcc agaaaaggct caatatactg cactaggtca tttacataaa
    18421 caacaaaaag cttccgaacg tttaaatgca tactattctg gttctccact tcaatatagc
    18481 aaggatgaaa gagcgtatac caaaggggca tacatagtgg atataaaagc tggagaaaaa
    18541 ccaataattg aagatgtata ttttaataat tacaaaccta tagaagtatt taaatgtaat
    18601 ggaatagaag aagcactaga tatatgtgag caaaatcaag atagagagat ttggtcatat
    18661 tttgaaataa atactgatga gataatatca cagaatgaaa ttaaaaaaat gaaggaacta
    18721 ttaaaagaca taatagaaat aaaaccaata ataacatctt gttatgaaca agaaagtgta
    18781 gatataaaag aaaagtctat ggcagagttg tttagagagt tctattcttt tagtaaaggt
    18841 gtagagccaa aaggagaact tatggattta tttctagata taataagtga agaaggtgaa
    18901 tcagcagatg agaccaatta gattagaact tacaggactt aatagctata ttgataaaca
    18961 agttatagac tttgaaaaat taattgaaag aggtttgttt gggatatttg gaactactgg
    19021 aagtggaaaa tctacaatct tagatgcaat aactattgct atgtatggaa atatatccag
    19081 aaatacaaaa gaatatataa acagtgtgtg cgataaggca attatatcat acgagtttga
    19141 gataggaagc aaaaacacta gaagaagata cattgtagat agaaccattg ctagaagcaa
    19201 aacaggaaca aagacctcta atgctagatt aatagaagta ttgaatgaca atatccaaaa
    19261 tgttttagct gataaagttg tggaagtaaa tgaaaaagta gcacaggttg taggattaac
    19321 ggcaaatgat tttactaggt cagtagtttt accacaagac aaatttaatg agtttctaag
    19381 attatcacgt gcagatagaa gagacatgtt agagagaatt tttaatcttg agaaatatgg
    19441 aagaagtctt ggagaaaaag tgaaaaagag aaaaaatata cagttacaaa atttaaaaga
    19501 tttgaaatca aaattaagtc aatatgatgg aattacagag gaagtataca acaatataaa
    19561 ccaagaatta atagagttaa aaaatttgga aaaagataag aataatgctt tagacctagc
    19621 tcaaaaatct tatgaagaaa gtaaaacagt atatgaagaa caattaaagt tagaaaaaaa
    19681 tgaacttaga aaaaatgagc ttgatttaaa aaatagtgag ataaaagaaa agattgctct
    19741 tgtagaaaat gatagtaacg ctaaaaaggt agacccatac ataagttcag ttcaaaatct
    19801 agaaaaaaag atagatgaag atagctttgt agtaagtaat ttagaaaaga aattagcaat
    19861 attaaatcag gagcttgaag ttacaaaaaa tagatatgaa aaaataaaca aaattaagaa
    19921 tgaagaagtc cctaaattga gtgaagaaaa aataagattg caacaagcaa taaaattaga
    19981 agaagagtta gttttattag atagagagtt aaaagatcta aaagaaagtg gaattaattt
    20041 aaataagact aaagttgaat tagaaaaagt aaagcaggtg tcagagtcca gaaaagatgc
    20101 agttactaaa tctataaaag aagttgaagg aaagattgat aaagtaaata taagtgcaga
    20161 attaaaacaa aaaatatttc tagcatatga atacgagaaa gattacaaca acgtattgga
    20221 agaaaaaaat caaaagctaa ataaactaga agaaatactc aaagagacag aaaatataaa
    20281 tttaaaagtt agatatattg ataaagataa gaatgatgta aatcgtaatt tagaaaattt
    20341 atcacttcac ttggatgttc ttcttaaaaa atgtcctggt aagagtgctg atttactttt
    20401 aaaatctgaa tatgttactg aattaagaag taaagcaaat aatactaaag aaaatgaaat
    20461 taagaaaagc agtatacaag atgaattaaa gataatactt gaaagtaagt ttaatactga
    20521 aagggaagta aatttactaa atgaaaaact tgaaaataat agaaagaata gagatgacct
    20581 agaaaaagaa ttagaagaac taaagtattt aaatttagcc tctgaactta gacgtgaatt
    20641 aaaagaaaat atgccttgtc cagtttgtgg gtcaaaacat catgaaaatc ataatataac
    20701 taagtatgat gaaaatatat cttttgtcaa agaaaaactg gagaaattag aaaaagaaaa
    20761 aataagtata agaaacaata tagaggaatt aaatgctaaa gtaagtgggt atttatctat
    20821 agaaaaaatg aagactaaag aacttgaaga tgtaaaagga aaactagggg ggattccatc
    20881 tagtcaatta ttaaaaaaac ttgatgaaga acaaagaaaa cttgcattgt taaaatctaa
    20941 tattcaggag tgggagaaag aaaaagagag tactgaaaat aaagtaacat tagctaaaga
    21001 agaaaaaaat aaaattgaaa aagaagaatt aaaaataaga gagagtctga ataattataa
    21061 gaaattaaca agagatttaa acatagaaat agaaggttta gaaaataaat gtaaaaaact
    21121 taaacaggaa tacctaggat taaagacgat tactaaagtc tctaatctat tgtcaaaagt
    21181 aaaagaaata agggagaatg aaaaagaatt agaattacta agtactgggc attcaaattt
    21241 attaaaaaat agagactcac tagatattaa aataagagaa aatgagagta aactacatga
    21301 aatagagata gaattaataa aggctagaga attatatgta gaaaagaaat tgagtagaga
    21361 taataagtat aaagaagtta ttaacataac gaaaggtgat ttagctaaaa atcttttaca
    21421 taatgttgaa gaaaatatat gtaagatatt agaacaagaa gaatcaagta agaaaaaatt
    21481 ggaagagcaa agattagaat atgaaaaaaa cattgctgaa aagcacaata tagatggtag
    21541 acttaaaact gctaaggaac aatataaaga ccaaaaatca acactaaata aactattagc
    21601 agaaaataaa tttgaaagta tatatgcagt aaaaagagct ttattagata ctgatgcagt
    21661 aaaaaaattg attgaagaaa tactagagca tgaagaagaa caaaagttat tatcatttaa
    21721 gataaaatca tcaaaagaaa aattaaatgg aagaagcata aagaaggagt actttgaaca
    21781 gttaaaagat gaaatttata atttgaaagt agaaatagga aatatatcca aagatattgg
    21841 agctaatcaa aatcagttaa taacactaaa agactcttta gataagataa atgattttaa
    21901 taaacaactt aaggtagttg aacacaatgt ggacttattg gaagaattag ataaatgtgt
    21961 gcaaggaaat aaatttgtag aatatgtttc tacaaaccaa ttaaaatata tagcattgga
    22021 agcatcaaaa cgattggatg gaataacaaa aggaagatat gcacttgaaa ttgactcaac
    22081 actaaacttt gtaatgagag ataactttaa tggaggagaa agaagaagca ttgatactct
    22141 atctggtgga gagacattct tgacatctct atcattagca cttgctcttt catctcaaat
    22201 acaattaaag ggaagtgcac cattagaatt tttcttttta gatgaaggtt ttggttcatt
    22261 agatagtgaa cttttagaaa ttgttataga atccttggaa agattgcata gtaataatct
    22321 aagtgtgggt ataataagtc atgtcgagga acttaaaaat agagttcctg ttaagctatt
    22381 agtttcatct agtgaggctg gaataggttc aaaagtaaaa attgaatata gttagaaaat
    22441 atatggtaat tgaatatatt atctaatatt tccaaataat atgtaattgt gatataataa
    22501 aaactaatat taaagttatt tataattaat attaatataa aaacatgtaa gtaggagtgt
    22561 ggtaagtgtt ggaatcgccc aataatttga ttcagattat ttttttaata gtattactta
    22621 tagggtctgc atttttctca gcatctgaaa cggccttaat gtcgttgagt aaaatcagaa
    22681 tcagatatat gcaagatgaa ggagttaaag gagctaagtt agtaagttca ttaatagaaa
    22741 atccaaataa gcttttaagt tctatattgg ttggaaataa cgtcgtaaat atagcagcaa
    22801 catccatatc aacatctttg tttataggat taatgggaga aaaaggagtg gcacttgcta
    22861 cagctgttat gacagtatta gtattaatat ttggtgagat tactccaaaa acaatagcag
    22921 caaataattc agaaaaggtt tctctattag tatctaaacc tataaaagca attatattta
    22981 tattaagacc aatagtatgg atatttaata taattacaaa tattatattt aaattatttg
    23041 gtataacaaa taaaggagct aaatcattca taactgaaga agagctaaaa actatggtaa
    23101 atgtaagtca tgaagaaggc gtccttgaaa tggaagagag agaaatcata aataatgttt
    23161 ttgaatttgg agatatgcaa gctaaaaatg caatggtaca aagaatagat atggtagcta
    23221 tagatatgga agatagttat gatgagataa tacaggtatt taaaactgaa aaattaagta
    23281 gaatgcctgt gtatgaagaa actatagatg atattgtagg aatacttaat ataaaagata
    23341 ttatattttt atctgatgaa gaaatagagt catttgatat taaaaattat atgagagaac
    23401 cttttttcac gtatgagttc aaaaagataa cacaacttct tgaagagatg aaacttgaaa
    23461 aaagtcagat ggctatagtt gtagatgagt atggtggaac atctggactt ttaactatag
    23521 aagatttagt agaagtcatt gttggagata tagaggatga atatgatgaa gaagaggatg
    23581 aaatacaagt tataaaagaa gatgagtata ttgtagatgg aagtactaaa attggtgatg
    23641 ttaatgaact tattggtgta aacttggaat ctgaggagtt tgattccata ggaggtttta
    23701 taattggaca cctaagcaga ttgccagaag aaaatgaagt aattgaagtt gataatataa
    23761 gattttgtat agaaagtata gaaaaaaata gaattaaaaa aataagaata tatacataat
    23821 gtaataatgt tcttaaattt attagaagtg tataaatata aaagatatct tttatattta
    23881 tacacttctt tttattttgt attcaaataa aactagtatg aaatggacaa aataaaaata
    23941 taaattagaa gaaaggagat ttttaagatg agcatactag aaaataattt tttatacaaa
    24001 ttaaaaaaca acactatctt tttttgtata tatacattgt tatttatttt tatttacaaa
    24061 gcgtttccat acatagctcc attttttcta ggtgctataa tagcacttat gattaatcct
    24121 atatcacaaa agttagaaaa taagtttcgt ataaataaag gtatctctac tcttgttcta
    24181 agttttcttg cagtggctat agtcagtaca gttactacaa taatagtaat aaattcaatg
    24241 aaagaattaa tgggattttt aaataatata tctgctaatc ctgaggatat aagtaatact
    24301 attatgtatt ttttaaataa aataaatgac tttatgaaat catttcaaga aatagccaat
    24361 tttgatgtag aacaattagt aaacaaattc agtggtgaag taatgcaaat tacaaaaaat
    24421 cttcttacta gtatacttgg attggctact tctattccat atattataat atttataatt
    24481 accttgttta ttgctaccta ctttatagca aaagaccttg ataagattga aaatagtttt
    24541 tataatatgt ttactgttga tgttagaaag aaggtaaaaa acgtaaagaa agaggcaggg
    24601 ctttcacttg ttggatatat aagggcctat acaatactta tggctataac attttttgca
    24661 atctggggaa gttttgcttt atttggattg aaatacggtc taatagtagg gtttgtaggg
    24721 ctttaatgga tttaattcca ttcctaggta taataacaat atatcttcca gtaattgttt
    24781 attattttct tataaaaaat tattttatag ctataagtat gactgtgata ttttttgttt
    24841 tgtctttgat tagagaaata cttgaaccta aactagtatc agtaaatgtt ggactaaatc
    24901 cattagctac cctagcagcg atttttattg gaatccaagt aaaaggaata attggagtaa
    24961 ttttttgttt gggtttggta tgtatgcatg atatacttaa gaaggtggat attttttaat
    25021 tataataatt gatagatttt tttaaaaata aaattttatt cacaggtaaa taaaaaaata
    25081 ttaatcttat taagaaagag ggtatatacg tgaaacaaaa agtagtggaa agatttttaa
    25141 aatatgtatc atttgataca acatctaatt ctcagtgtga gaactgtcca tcttcagaag
    25201 gtcaaagagt tttagctaag tatatagttg aagagctaaa aacaatgggt gttgatgatg
    25261 tgagtttaga tgaaaatagt tatataatgg ctactttaaa aggaaatact gatggtgtgg
    25321 atactatagg attcatatca catttagata caattgaaga tgttagtgga aaagatatta
    25381 aaccaagaat aatagaaaat tatgacggaa aagacatagt tttaaatgaa gcgttaaatg
    25441 ttattacgta tgtaaaggat tctccagagt tggaagaatt taaaggtgac gatttaatag
    25501 tcactgatgg aacaactcta cttggctctg atgataaagc tggtatagct gagatagtga
    25561 ctgcaataga gtatctaata aatcatccag aaattaagca tggagatata aaaataggat
    25621 ttacaccaga tgaagaaatt ggtagaggtg ctgatttatt tgatgttgaa aaatttggag
    25681 caaaatatgc atatacttta gatggaggaa tagttggaga acttgaatgt gaaaatttta
    25741 atgctgcaaa tgcaactatt actatacatg gtagaaatgt tcatccaggt tcagctaaaa
    25801 ataaaatggt aaatgctata catatagctg ctgaaatatc agaaatgttc ccagcagatg
    25861 aaagaccaga aacaacagaa ggatatgaag gattttggca tttaaattct ataggtggaa
    25921 atgtcgagaa tgtaagtatg gcttatatta ttagagacca ttgtagagaa aaatttgaaa
    25981 atagaaaatc tattatgata gagaatatag aaaaaataaa taagaaatac gataatagag
    26041 tggaattgga tttaaaagat tcttattaca atatgaaaga aaagattgag ccagttatgt
    26101 ttatagttga tatagctaaa gaagctatgg aggaattagg tataaaacca cgtttagttc
    26161 ctgtaagagg tggtactgat ggagcaagat tatcttttaa tggattacct tgtccaaata
    26221 tatttactgg tggattaaac ttccatggga aaaatgagtg tataccagtt agttctatgg
    26281 agaaagctac taaactaatt gtaagaatag ctgaaaaata tgctgaaaga gtttagttaa
    26341 aaagtattta aaaattaagc atttaaagtt ataatagcta tatcattctt tataagtcaa
    26401 gctgattata agcttgtgtt gtatttaaaa tggtatagct atttttgtaa ttatttttat
    26461 aaaagataat tatttttagt ttagggtatc aataaaaagt atggatatca ataggtatta
    26521 acatttaaaa gggggaattg tattgaaaat taaatctaaa aaaataatag catttgcact
    26581 ttcacttggg attatgttgc caagttgtgt atatgcagac actattagta aaaatcaaaa
    26641 tgcacaggta gatatgaaca attatcttca aggtagaaaa tctccaaagg aggaaaaact
    26701 tattggtgaa gatagatttg atacagcgat aaaaatatct caaagtggtt ggaataatgg
    26761 ttcagaaagg gtgtttctag ttaactcaaa ttcattgcca gatgcattgg cttcaactcc
    26821 tttggcaagt aaattggatg caccaatact gcttacaaat aaaaatagta taccatataa
    26881 tgtaacagag gaaataaaaa ggcttaatcc agcagaagtt attttaattg gaagtgaagg
    26941 agctatttca tcaagtgtaa aagaatctct tgaagatatg gaagtattag tcagtagaat
    27001 cggtggagca gatagagaag aaacatcttt acttcttact agacagctag atgatactgg
    27061 tgatttaggt gtctcaaaag tggcagtggt taatgggtat aatggactgg cagatgcaac
    27121 ttcaatatca agcccagctg caagtgataa tacagctata atatatacag gtaaggatag
    27181 cataagaagt gaggcaaaga attttattac acaaaactca actaagacat acatagtagg
    27241 tggggagtac agtataagta aaaaacttga aggacagtta gtaaactcag aaagactagc
    27301 aggaacagat agaaaagata ctaatgcgaa agttttagaa aagttttatg gaaaatcaag
    27361 taaggttaat aatatgtatt ttgcaaaaga tggaagtggt agagaagctg atttagttga
    27421 tgggcttgct gctggagtat tagcatcaaa aacaaagtca cctgtagtac ttgcaagtgg
    27481 aagtttaagt agtgcacaga aaagttttat aaaaaaagta aaggctgata aatttgtaca
    27541 agttggtgga ggtaaaaata gtaaaccata tgcagaagca ttagccttac agtaatattg
    27601 tgtaaatcaa aattaatata taataatagc aagtaaacca agttgaactt caatatatat
    27661 aataaaataa gtaaactaag ttatatttca gtata
//
LOCUS       DAMJYN010000052        26259 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.053, whole genome shotgun sequence.
ACCESSION   DAMJYN010000052 DAMJYN010000000
VERSION     DAMJYN010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 26259)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26259)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26259
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.053"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     repeat_region   545..901
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=545..573
                     /rpt_unit_seq="gttttagattaactatatggaatgtaaat"
     gene            1140..1328
                     /locus_tag="PC466_002352"
     CDS             1140..1328
                     /locus_tag="PC466_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769722.1"
                     /translation="MKIITDSSRADYFKQRRQNKKTFSVLLDREKVEKIEEHLKKQNK
                     TKTIWLEEKINEELEKEE"
     gene            1447..2313
                     /locus_tag="PC466_002353"
     CDS             1447..2313
                     /locus_tag="PC466_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage repressor protein"
                     /protein_id="HDF2769723.1"
                     /translation="MKNLIVKEFNGSQIYTFMWKEKSCWIANQIVGLFDYADVSKTIQ
                     DCIKAEDFEIEQEYDVLKGNEFNDFVTTLNVVANNIISNKARSITIFYEDGLYGFLQY
                     TDKPIGVQFRKWLRREVLPSIRQTGAYITNNANPEKLREKASEIEKLQLAYNSTSMLK
                     ELLDGAGFDNKSKLLTAKTLYKKAGIDLPIEINEEEHYFDTKQIASKLKIYSKSNKPA
                     QLAVCEIIKKIDLEENEVKGVWETNGSWTGTVNKYTKSVIDKVRNWIEENNRPTKIAG
                     EKKNYHVVYKIE"
     gene            3178..3705
                     /locus_tag="PC466_002354"
     CDS             3178..3705
                     /locus_tag="PC466_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4352 domain-containing protein"
                     /protein_id="HDF2769724.1"
                     /translation="MREGKRRRGCLFWFILIILFSGVVGAIAGNSTNNESTEKQKEDL
                     TKYIGEEGSIGDLKLTVNSISKASEISVASGYLAYTPDSGKYGIINLTIKNQTKESQS
                     FMLNSFTLIGPDDSKYVPSLLIDVGNKYITMDTVNPNLDVTGNIAFEIPKDLLVSDCK
                     LKYSGSEQEFILKEK"
     gene            3843..4610
                     /locus_tag="PC466_002355"
     CDS             3843..4610
                     /locus_tag="PC466_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4428 domain-containing protein"
                     /protein_id="HDF2769725.1"
                     /translation="MGLFGKKKADICCICNTEIGVLNIEDGWICNSCFKEYCDALSMT
                     KAPKILRKLDIEKTISSTKKNNELQKIFNTTNNIENYIEFDEDNKKWLVSKKSINDKK
                     TPIIHSYEDIVKFELLENGETVTKGGIGRALAGGILFGEAGAIVGGITGKKTTRKVVD
                     TFKIKITINNIDNPIEYIELINKKTKTNSSAYEKAYKDAHKILSTLSAITQSIKETDN
                     INTKSVADEILKYKNLLDMEAITQDEFNTKKKELLNL"
     gene            4676..7048
                     /locus_tag="PC466_002356"
     CDS             4676..7048
                     /locus_tag="PC466_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HDF2769726.1"
                     /translation="MATIQTSIKIFDGMTPAFRNMTTSINTTINSLERLQQRLHNPLN
                     TGGIQASQQSLNNIENILTRIEQKIGRNTNEQENFNNKIKQGSEAGSLLVSKLKSLAG
                     IYIGIRGIESITKAADTIASTKARLNLMNDGLQTTEQLNKMIYLSAQSARASYADTAA
                     QVAKLGILAGDAFGSSAEVIKFTELMNKAFVIGGTSANEASAAMYQLTQAMGAGKLQG
                     DEFRSIMENAPLLATKIADAMGKTKDQLKELSSSGAITADVIRNALFKASDEIEKKFA
                     SMPVTFSQALTMMKNDAYMIFGQTLGKISGALQSVRFSEIVVSIRNVMIAISSNIYDT
                     LNIIKNILNSEFFSNLVQGFTFCAVVITKSLGSIVNTALNIVNIFAQNWSIIKPIVFG
                     VASVFILFRGVLLATKIATIGNVIANVAHAASSSLSALMTNIQAAALMRSNGATLSAT
                     IATWGLNAALLACPITWVVLGILAFVVVVFVAVAAVNKFAGTSLTALGVIVGAVFAAV
                     AAIQNVMIWLLNGCIAVNEGITNGWNQCVYLMKQAIAKGVIFIIEKMASLNNSVNNAG
                     NALGKAFIDGANIAIRGVNKLIDLINKIPGINIGKVGEATFTPVKADNSYIKQQIDSL
                     NRWVGDAPEKVKLERMGYKDIGAAFQKGNALGTKWQNAITDKFKDTFDINKMLEDAKK
                     KLGLDDLWNKQNPLNNLGGFGGDLGKNVKDTAGNTAKMAKTMDKSQEDLKYLRDIAEQ
                     ETINRFTGVNIKIDMNNTNNISKDTDVDGIVNVLTEKLNDAMVVSAEGIV"
     gene            7065..7754
                     /locus_tag="PC466_002357"
     CDS             7065..7754
                     /locus_tag="PC466_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HDF2769727.1"
                     /translation="MAYDFYLDGVQLPIAPPKLEVKVTNKNKTVDLINTGEVNILKKE
                     GLSEISFEAEFTHNKLPFCRGQFRDVQFFLSKLELLKTDCKPFQFIVSRELGNKVLFN
                     TNIKVSLEEYAISEDADNGSDTKVAIKLKQYRDYSTKKLVLAPPKNETGRPNVKIEPK
                     RVDSVNATNTKTYTVKAGDSLWSICQKQLGNGSLYKKVYELNKSMMDKANKGKNLSKY
                     TIYKGQVLKLG"
     gene            7747..9639
                     /locus_tag="PC466_002358"
     CDS             7747..9639
                     /locus_tag="PC466_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HDF2769728.1"
                     /translation="MVDELVLANDRDVRLVIAHWEDFYEPAVIDGITWEIERRGTPSK
                     LEFTIVMDDILEFCEGNSVRLYYKGIGIFYGYIFQKKRDKENHIKIVAYDQLRYFKNK
                     DTYVYSNKTASELVKILAKDFNLKYNVIEDTKYKISRVEENKTLFDMILTALDDTLRE
                     KKEMYTLYDDFGRITLKNVASMKLDTVMNNDVIEDFDYNSSIDSDTYTKIKLVRDNEE
                     SGKRDVYIAQDSAHMRSWGILQMFDTVDKNMSEAEIKQKCDILLKLYNKKTKSLSLKN
                     ALGDIRVRAGCLVPVFLNLGDIELQNYMLVEKVKHTFENNSHFMDLTLVDGDEFASYS
                     SSSYSSGNTNNKDEKKNGPAQSIMKKNTGKKVPAIFTAYYPGNNAMEGGKTDCNGKPL
                     DVKSRTVAGPMNREGVKKTWYTDDFLNKHPVFEYGDKVKIILPGTAYDNKVYTVKDNG
                     GRIYVETNGTYHIDILLANASECKKFGRKNGYIIIGGDEEQTYQVEGNNQSNTNNNSK
                     EDKLISIAKSKLGCNYVYGAEGPNNFDCSGFTQWCYKQIGIKIPRTASAQSKAGKAVD
                     LKDRSKWKAGDLLCRIGGGSSNHVVMYIGNNQIIHSPQTGDVVKIESVNSYRKGKAYT
                     HVRRFI"
     gene            9653..9913
                     /locus_tag="PC466_002359"
     CDS             9653..9913
                     /locus_tag="PC466_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2577 domain-containing protein"
                     /protein_id="HDF2769729.1"
                     /translation="MSQDLLQIIKKAAMDAVETSNPMRVVFGTIESISPLRVKIEQKL
                     SIGEIFLIQTDTFKRYTDKKMGDKLVLIRMQGGQQYLILDRM"
     gene            9918..10337
                     /locus_tag="PC466_002360"
     CDS             9918..10337
                     /locus_tag="PC466_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2634 domain-containing protein"
                     /protein_id="HDF2769730.1"
                     /translation="MLPSDNLDYDIEDVSIINFDVRQEPSKTFKLHIEKSKIDGICDD
                     VEALKQTIFLILNTERYEHLIYSRNYGVELNDLIGEPISYVIPELERRITEALIQDDR
                     IENIDNFEFQNIKGKVQCRFSVHTKYGNIKAEKVVSV"
     gene            10338..11387
                     /locus_tag="PC466_002361"
     CDS             10338..11387
                     /locus_tag="PC466_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HDF2769731.1"
                     /translation="MFELMTFENIIKRMLDSVPDTFDKREGSIIYNALAPVAIELTET
                     YIAMDELLDQTFVDTASYYYLEKRCKERGITPLEATHTIAKGVFNIDIPLDSRFNLGE
                     YNYVAIERISEKTYKMKCETTGPVFELGKLIPIEYIDGLETAELTEILINGEDEESED
                     SLRQRYYDSLNSQSFGGNIQNYRDEVNKIQDVGGVKVYPTWDGGGTVKLVIINSNFKV
                     PSEELVNLVQEEIDPIGHQGEGLGLAPIGHRVTVEGVTSTTINISAEITYKNGYTWEN
                     IKSIAEEAIDDYLNELNMSWEDEENLIVRISQIETRLLSIDGVLDIANTMINDVKSNL
                     TIDSNSIVVRGEVVG"
     gene            11380..11997
                     /locus_tag="PC466_002362"
     CDS             11380..11997
                     /locus_tag="PC466_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmfQ family protein"
                     /protein_id="HDF2769732.1"
                     /translation="MDKEINLINYLPQILQDKEEYIKVFNVENKEIKTLHDKLKDLSN
                     DQFLEDLTISGIKRWEKIMSITPKSNESLEDRRFRIFSKYISKLPYSERFLRNWLDNV
                     VGEGNYELTINNATYNIHLESDARNQDWFEEVHSFVSNIKPCNMTLDYTRVLISKDNY
                     MNFGITTLMGQEITIYPWSPPDIETYGEIDVLTGNGVGYQEITIF"
     gene            12009..13034
                     /locus_tag="PC466_002363"
     CDS             12009..13034
                     /locus_tag="PC466_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDF2769733.1"
                     /translation="MAIDKSYYTIITDVGKAKIANASVTGNKVGFVKIQLGDGGGSEY
                     TPTESQTELKNVVWEGNIGNTTTDETAPNCIILESLIPSSVGGFMIREIGYLDDENNL
                     IAISKYKECYKPSIEQGAVVDMKVKTVLIVSNINNIELKIDPTIIFATLKDIQDLDAK
                     ISNVNTKIDTTKTELTSNIETAKTELNTRIDTENEKQNIKIDQLIAGGSNVASTQTIT
                     IDDWIDNQEGGFKATVTHGLLTQRITVSIIDATTKDNVVPDFTIIDDNSIEVRSGVKV
                     ELNVYVINGNAETHFINATVDDNRVSEMTTYSSKKIHEEIGKVAEQLTGINSNIISTV
                     NNDILPI"
     gene            13051..14577
                     /locus_tag="PC466_002364"
     CDS             13051..14577
                     /locus_tag="PC466_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769734.1"
                     /translation="MALSMSYFNLPDKRKYTKNLAFNPFAGGRQNFEWTGGDHGLNGE
                     FKETCLSCTYNGSTLNWGSGNVWVLGEYGQYTFTYNCESMHVDTQQKFPYTSNRIITI
                     KGRPVISGSDTSLGNKRKGFSVDFTVSDDTPNVNLIVRAYLDDKLIQNITPVVQNSTL
                     TATVTDSQLNSLSVDGNHKLKIQLNDGYDNFDRIFTFKKIEKGIDISTSLVTDSQAKF
                     TVTKIYSELTKIECYLDETLKETFTTDLYSEKTINYELIDNAIHTLKIVVTDAENVVE
                     EKVISISKNIMPLQPDATLQDISTKLTEIGQGVRNGKTSIINTLALKNIDASLNNTLV
                     ELSEKIKGGFDSGDASLQDLMNQLTQANNTISQLNTKYKVASGTVTSFADSTKIAYPY
                     LTDNVTKPGSWIKVSNLGFKPNIFFADFDYYDAEYKNNYKLFLFACNGVATQRGVDFS
                     SVTSFIRKSGDEYFHANGWLYSNSEGDVYFNNTGVQIPAYNFDSTQKHTYKWYAIKFI
                     "
     gene            14592..14885
                     /locus_tag="PC466_002365"
     CDS             14592..14885
                     /locus_tag="PC466_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769735.1"
                     /translation="MNVPNRIIYDQTGRTIFETGESCGDVLPHYTITELHYIDIEYGS
                     IDYTRNRVIGINIETKEPILEEIPVYITDEEKRIQELENQLLIAENEKVGGLL"
     gene            14885..15067
                     /locus_tag="PC466_002366"
     CDS             14885..15067
                     /locus_tag="PC466_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769736.1"
                     /translation="MNINNVVVRILAERILSKGLNPLKNREFQLDDVTNTEYRKAVED
                     YIIKNSGVVEGAEPTI"
     gene            15101..15667
                     /locus_tag="PC466_002367"
     CDS             15101..15667
                     /locus_tag="PC466_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769737.1"
                     /translation="MTFKELVNKVRNLVLEAKNVTIEDTESKFTSENVEGALKECIDR
                     ADEAFQEADSGKTLLSTAIGSPTTSEQTFQDYANYITGFKSNISNLETQLKSKYSIRY
                     GPIDGYDGNPFSANFGKSASYLIVYVYFRRSVYYYNPSGSSLGSNTGGSERAWITINS
                     NKTGFSVHSYDTSYESYPFTGYYIACFA"
     gene            15698..15988
                     /locus_tag="PC466_002368"
     CDS             15698..15988
                     /locus_tag="PC466_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769738.1"
                     /translation="MEEISINLLCAVAGVVISYLAFRNNSNRKIQDETETTTKLEQQI
                     TFLCENVRDIKHDVAKFNTSFLDISERVAKIEASTKQAHLRIDEIVNRIGGK"
     gene            15992..16249
                     /locus_tag="PC466_002369"
     CDS             15992..16249
                     /locus_tag="PC466_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HDF2769739.1"
                     /translation="MDNLISFIPEQLLILVAALSIIGKGCKKYKQLDNKYIPVVLLIL
                     GIGFSIWMLGLNPVAVLQGVICWGVAIGINQTYKQLKDGEK"
     gene            16510..17373
                     /locus_tag="PC466_002370"
     CDS             16510..17373
                     /locus_tag="PC466_002370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Abi family protein"
                     /protein_id="HDF2769740.1"
                     /translation="MVEVKEEKTFDEQIDILKSRGLIINDKEDAKFVLSNVNYYRFTA
                     YLLSFKNDDGSYKEGTTFEEVYDIYRFNKEFRILLTDLLGSIEIAFRTYIAYTLAIKH
                     GACGYLERESFKDEKFYINFLTALEREKSNNSDKLFIIHHKEKYEGKLPIWVATEIMT
                     FGMLSKLYSNMLPEDTRYIKNNLCRVNTLLVKSWLQSLTQVRNQCAHYGRIYNNNFRI
                     ITIKNEYKKYNLDNKKIFSYILAMKHLTMDKLIWNSFFIKLQKLINDYNNSIDLKLIG
                     FPNNWIEILAK"
     gene            17452..18264
                     /locus_tag="PC466_002371"
     CDS             17452..18264
                     /locus_tag="PC466_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDF2769741.1"
                     /translation="MKICITVGHSILKSGACTSADGVVNEYQYNKSLAPVLADTFRKE
                     GHKADVIICPEKQFKTKAEEKTYKIPRVNSGGYDLLIELHLNASDGQGKGSEVLYYSN
                     KGLEYATRICNKLGTVFRNRRAKLDKGLYILNSSNPTAVLIESFFCDNKEDYEKAKKL
                     GHEGIAKLIVEGVLNKNINNEGVKQMYKHTIVYDGEVDKISATVVGWGYNDGKILICD
                     IKDYVPGQTQNLYVIGGAACEKIGSMTKEKFTMIKGNDRFDTLYKALDFINR"
     gene            18358..20757
                     /locus_tag="PC466_002372"
     CDS             18358..20757
                     /locus_tag="PC466_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HDF2769742.1"
                     /translation="MIFKKYIKSLLIVVSVTLIMNKSILFVNALDLESNNNIKSYKRK
                     NVKEIDISNKFVDESFRRDIVEKVLDNRDDPLTNEVASKDNYKIYESDLNKIESCLEL
                     DLHKNPDVSNPNKIDNLDGIENFRNLEKLDCSSNNLESVDLSKNIKLKYLDISGNKIL
                     NIDLKNNNLINELHCDANKLSNLDLKNNKNLVSLFFTSNELTEIDLSNNVNLENLQFL
                     NNNLKSIDLSHNKKLKSLNCTNNKLKSLDLSNNVFLKNLSCSGNNLSKLNIKGLTSLE
                     YLGCAKNKLQDLDVSTNIKLDSLLCGKNSLTKIDISKNKELNSLECSGQYIEKSIIKN
                     GENIVVDIGIENSKLKELYPQNYNISTGFLTWENLSDFPNSISYSLEYEYGPVNDTET
                     MDVNISIDKLVKCRIRYIDYDGSIINEKEISDNSSINEIQINPQRENYEFSGWRNNKD
                     EKIYTSEQVSKLVFDDSTDFIATYKRKSTGSSGSSGGTSSKEDFNIAPSKEKITGADR
                     NETSVKISQKGWNKADNIVLINDSSISDALSATPFAKSKDAPILLTKNNNLNKLTEKE
                     INRLEAKNVYIVGGLKSVDEKVVSDLKKKGLNVIRISGNDRYETSIKLAKELDKNSNL
                     SKVVVVNGEKGLADAVSMGAISAKEEMPILLTNQNDDMKDIKDLIANKNISKSYVIGG
                     ESLFNNKEVNNTLPSVTKIAGSDRTETNSKVISHFYSKDTLNDLYVAKNGMNKQDDLV
                     DALSVGVLAGKTESPVVLVGNGLDDSQKELIKNKKFKNITQIGGNGNEKAFNEVENLV
                     K"
     gene            complement(20798..20983)
                     /locus_tag="PC466_002373"
     CDS             complement(20798..20983)
                     /locus_tag="PC466_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB/MazE/SpoVT family DNA-binding
                     domain-containing protein"
                     /protein_id="HDF2769743.1"
                     /translation="MILLEQRKLRIGFNKSGKGSFTPRLILPMSWIKEMNISPDERDV
                     LVTFEDGKIIIEKTENE"
     gene            21678..22355
                     /locus_tag="PC466_002374"
     CDS             21678..22355
                     /locus_tag="PC466_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HDF2769744.1"
                     /translation="MFKHDKALLKEVKVERPNPQYAVLMQEQLGGANGELKAAMQYLS
                     QSFRIKDPQIKDLFLDIAAEELSHMEMVAQTINLLNGHDVDYNAVNTGEIETHVLTGL
                     SPVLINSSGAPWTANYVTVTGDLVADLLSNIASEQRAKVVYEYLYRQIDDKYVKETID
                     FLLNREEAHNALFRDALNKVKDTGSNRDFGVTEDSRLYFDLSTPGPNHNTKIDINPPS
                     FEKPLKK"
     gene            22529..24565
                     /locus_tag="PC466_002375"
     CDS             22529..24565
                     /locus_tag="PC466_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin domain-containing protein"
                     /protein_id="HDF2769745.1"
                     /translation="MDSNRKPNNLINEKSPYLLQHAYNPINWYSWNDEAFKKAKEEDK
                     PIFLSVGYSTCHWCHVMEKESFEDEEVAEIMNRNFVAIKVDKEERPDVDSVYMTVCQA
                     MTGSGGWPMTIIMTPDKKPFFAGTYFPKYSRYNRPGVIDLLKNVSEKWNTSRDILIKS
                     GDEIIEALKDDFGVKNTEGDLSKEMLSSSVRVFKAIYDEKYGGFGNAPKFPSPQNLMF
                     LMKYYSIEKDKDVLKMVEKTLDGMYRGGLFDHIGFGFSRYSTDKKWLAPHFEKMLYDN
                     AMLTIAFLDAYKITKKELYKEIAIKTIDYVVREMKDKEGGFYSAQDADSEGEEGKFYT
                     FNPLEIIEVLGEEDGTFFNNYFDITSSGNFEGKSIPNLIKNKEYERHNEKIADLSKKV
                     FEYRKERTSLHKDDKILTSWNALMIVALTKAYSTLKNDIYLEYSNKCLNFINNNLVNE
                     SGRLLARYRDGSSDYLAYLDDYAFLIWAYIELYESTFNMKYLEKALNLNESCINLFWD
                     YEKSGFYIYGKDSENLIARPKDLYDGAIPSGNSVQLYNLIRLAKITGDNRLEEMSYKQ
                     LKLYVDNVKSSPTGYSFYMLSLMFELYSTKEIICIFKEDSDLIAFKELISENFIPNAT
                     FLAKKYNEENTIIGFLNNYRLKDDKTSYYVCQSNSCSQPINDLQKLKDMILGVE"
     gene            complement(24756..25322)
                     /locus_tag="PC466_002376"
     CDS             complement(24756..25322)
                     /locus_tag="PC466_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF2769746.1"
                     /translation="MDYSNELKELFLMNQTYATLFTLTNKIQIEGDKYFGILTSRQYM
                     TILSILHLPEEETTLNNIARKMGTSKQNINRLVANLEKNGYVDVIPSPHDKRAINVKV
                     TDLGKKVMVTCSRTGINFMADVFHEFTKDELETLWSLLKKMYRFNGEEQDGFEEDANF
                     MEYEEIDKIKSEALEEFAKRRNRVNKND"
     gene            25606..26133
                     /locus_tag="PC466_002377"
                     /pseudo
     CDS             25606..26133
                     /locus_tag="PC466_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436568.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
BASE COUNT        10592 a         2869 c         4624 g         8174 t
ORIGIN      
        1 tgaatttcat tgtttatata aaaaaaatgg aaaaatatgt aataattata ggttataata
       61 attgtagcaa ggataataat cgaaagtgcg aagggtgatt attttcatat taaacgccaa
      121 attccaaata aggaaggagg tgaaattata tgataggttt tttattaagc atactagctg
      181 gtgttatatc agcttatatt tatgacaaaa taaaaaatca cccagacgcc aataagggtg
      241 atttaaaaaa ataatatttt cacttaacaa ctgaaaataa tcactctttg taggaataaa
      301 ttatttcctt gcttttatta taccacaaat tggtacagat attcaaaaat aatattttta
      361 tgatataata aaaatgtaga gattttgcag tgagcgatat ttgtgataaa ttgaagttta
      421 acagttgcaa tataaggcgt tgagggtgtg tgataaatgt tatcaattgc actactcatg
      481 gttcactgca aatttaagag agttgtatat gtgtaggtat tgaaaatact caacttattt
      541 tggggtttta gattaactat atggaatgta aatgttgtaa gaagtatcat tctatttttt
      601 aatctttctg ttttagatta actatatgga atgtaaattt cagtgagaat aagctttatt
      661 gtcgatgtaa cactcgtttt agattaacta tatggaatgt aaatagtaca tataatgagt
      721 ctttaacatc agttatgaaa ggttttagat taactatatg gaatgtaaat gattgtactt
      781 tagcgtctgc actagctttg tctatcgttt tagattaact atatggaatg taaattattt
      841 tacagatgaa caattacagt tacttcttga atgttttata ttaactatgt ggattcaaaa
      901 ttaaatagaa aaaagaaagc acttacttaa atagtaggtg cttttgtttt gctcaaatta
      961 cttaattata aagttgctaa gtacaacttt ttagaattat acaatataaa aatgcactaa
     1021 agtgattgat tttgctcaag ttggtcggtt gagtaaaata attagaaaaa aatgttaaaa
     1081 aactcttgaa aagtgtcgcg atacaatgta taattatatt atcgcgatac agaaaagagg
     1141 tgaaaattat tactgatagc agtagagcag attacttcaa gcagagacga cagaataaaa
     1201 aaacttttag tgttctacta gatagagaga aagtagagaa aattgaagaa catttaaaaa
     1261 agcagaacaa gactaaaact atttggcttg aagaaaagat taatgaagag ctagaaaaag
     1321 aggaataaaa aataagagac gttctccccg accaaagatt gaacatccct tattgacgta
     1381 tattatatac actaactata gtatacgtca ttccttgaaa aaattcaatt aaggagtgta
     1441 atagttatga aaaatttaat agtaaaagag ttcaatggaa gtcaaattta tacttttatg
     1501 tggaaagaaa aatcttgttg gatagctaat caaatagttg gattattcga ttatgctgat
     1561 gtatctaaaa caatacagga ttgcataaaa gcagaagact ttgagattga acaagagtat
     1621 gatgtattga aaggaaatga atttaatgat tttgtaacta ctttaaatgt agtcgcaaat
     1681 aatataatta gtaataaagc tagaagtata actatttttt atgaagatgg tttatatgga
     1741 tttttacaat acacagacaa acctattggt gtacagttta ggaaatggct tagacgagaa
     1801 gttttaccaa gcataagaca aactggtgca tacataacta acaatgctaa tcccgaaaaa
     1861 ctaagagaaa aagcaagtga gattgagaaa ttacagttag cttacaatag tacatctatg
     1921 ttaaaagaac tattagatgg tgcaggcttt gacaataaat ccaaactatt aacagctaaa
     1981 acattatata agaaagcagg aattgattta ccaatagaga taaacgaaga agaacattat
     2041 tttgatacaa agcaaatagc atctaaactg aaaatatatt ctaagagtaa taaaccagca
     2101 cagttggctg tttgtgaaat tattaaaaag attgatttag aagaaaacga agtcaaaggc
     2161 gtttgggaaa ctaatggttc ttggactggt actgtaaata aatatacaaa gagtgtaata
     2221 gataaggtta gaaattggat agaggaaaat aatagaccta ctaagattgc aggtgaaaag
     2281 aagaattatc atgtggttta taagattgag taaatttata agattgtatt aaataattta
     2341 gtttagtttt ggggggatta atacaatgca tgagaattta cttgatagta tagatattga
     2401 aaagagaaaa gaagaattta gaattaaact tttgaaaata agagaaacag atatagatat
     2461 atataataag atagaaagta tagtatataa actttcttag aaaaaattag agaaaaataa
     2521 ttaaataaat agataaagca cttggatatt tcactgtttc aagtgcttta tatggtaaaa
     2581 aatggtataa taaaatatag gaattttgca gtgttcgatt tttctactca agtatagttt
     2641 aacaattgga atacaaggca ttgagaaggt ttgataagtg ttatcaattg cactattacc
     2701 cgctcactgc aaatttgaga aagttatatg tgtgtaagtc ttggaaatac acaatttatt
     2761 ttggggtttt atattaacta tatggaatgt aaatctttgt aatggtagtg tatttaagat
     2821 tgaaacatca agttttatat taactatatg gaatgtaaat caacattagt agttgtcttt
     2881 atacacatag catcacgttt tatattaact atatggaatg taaatacagc tcccaagaca
     2941 tacaacgaat ctgtaacatc agtgttttat attaactatg tggtatgtaa aagacttatt
     3001 tacagcttta tttgctaaat cagaaggttt tatattaact atgtggactt aaaattaaaa
     3061 ataattaaaa aacacttact aatgtaggtg tttttttatt gaaaggaagt gattataatg
     3121 taaaaatttt gaagatatag tataatattc ttataaaata taatttaggg ggatattatg
     3181 agagaaggaa agagaagaag aggatgtcta ttttggttta ttcttattat tttattttct
     3241 ggagttgttg gagcaatagc agggaacagt actaataatg aaagcactga aaaacagaaa
     3301 gaggatttaa ctaaatatat tggtgaagaa ggtagtatag gagatttaaa attaactgtt
     3361 aatagcattt caaaagctag tgaaatatca gtagcatctg gttatttagc atacactcca
     3421 gatagtggca aatatggtat tataaattta acaataaaaa atcaaactaa ggaaagccaa
     3481 tcttttatgc taaattcatt cacattaata ggaccagatg attcaaaata tgttccatct
     3541 ttattgattg atgtaggaaa taaatatata actatggata ctgtaaatcc taatttagat
     3601 gtaacaggta atattgcatt tgaaattcct aaggatttac tagtttctga ttgtaaacta
     3661 aaatatagtg gttcagagca agaatttata ttaaaagaaa aataatatat agatttaaaa
     3721 atatgaagca tttactttaa ataagtaagt gcttttttaa ttaaaaggag gtgataataa
     3781 tgtaaaaatt ttacttatat agtataatta cattataaaa ttattgtact ggggggaatc
     3841 ttatggggtt atttggaaag aaaaaagcag atatatgttg tatttgtaat actgagatag
     3901 gagtactgaa tattgaagat ggttggatat gcaattcttg ttttaaagaa tattgtgatg
     3961 cactttctat gactaaagca cctaaaattt taagaaaatt agatattgaa aagactatat
     4021 catcaactaa aaaaaataat gaacttcaaa aaatatttaa tacaactaat aatatagaaa
     4081 actatataga atttgatgaa gataataaaa aatggcttgt gtctaaaaaa agtataaacg
     4141 ataaaaaaac tcctatcatt cattcttatg aagatatcgt gaaatttgaa cttcttgaaa
     4201 atggtgaaac tgtaactaaa ggaggaatag gaagagcttt agcgggagga attttatttg
     4261 gagaagcagg agctatagtt ggagggataa caggtaaaaa aacaacaaga aaagttgttg
     4321 atacatttaa aattaaaata acaattaata atattgataa tcctattgag tatatcgaat
     4381 taattaataa aaaaacaaaa actaattcta gtgcttatga gaaagcttac aaagatgccc
     4441 ataaaatttt atcaacatta tctgctatta cacaaagcat taaagagaca gacaatataa
     4501 atactaaatc tgtagcagat gagatattaa aatataagaa tcttttggat atggaagcta
     4561 ttacacaaga tgaatttaat actaagaaaa aagaattatt gaatttgtaa tataataaac
     4621 acttactaat gtaggtgttt ttttatatgg aaatttatga aaggagagtg agaaagtggc
     4681 aacgatacaa acttcaataa agattttcga cggaatgaca cctgctttta ggaatatgac
     4741 tacatctatt aatacgacaa ttaatagcct tgaaaggtta caacaaagat tgcataatcc
     4801 gcttaacaca ggtgggatac aagcatctca acaaagttta aacaatattg aaaacatatt
     4861 aaccaggata gaacagaaaa ttggaagaaa tacaaatgaa caagaaaact ttaataataa
     4921 gataaagcaa ggaagtgaag caggttctct attagtatct aaactcaaaa gtttggctgg
     4981 catatatatt ggaataagag gtatagaaag tattacaaaa gcagcagata caattgcaag
     5041 tacaaaagca cgtttaaatt taatgaatga tggattacag acaacagaac aacttaataa
     5101 gatgatttat ttatctgctc aaagtgcaag agctagttat gcagatacgg cagcacaagt
     5161 cgctaaactt ggaatattag caggagatgc ttttggaagt tcggcagagg tgataaagtt
     5221 tacagaactt atgaataaag cttttgtaat tggaggaaca tcagcaaatg aagctagtgc
     5281 ggctatgtat cagcttactc aagctatggg tgcagggaaa cttcaaggtg atgaatttcg
     5341 ctctataatg gaaaatgcac ctttattagc cactaaaata gctgatgcaa tgggaaaaac
     5401 taaagaccaa ttaaaggaat tgtcaagtag tggagcaata acagcagatg ttataagaaa
     5461 tgcactattt aaagcttctg atgagataga aaagaaattc gcaagtatgc cagtcacttt
     5521 tagtcaagca cttactatga tgaaaaatga cgcctacatg atttttgggc aaaccctcgg
     5581 aaagataagt ggagcattgc aaagcgttag atttagtgaa attgttgtat ctataagaaa
     5641 tgttatgatt gcaatatctt caaacattta cgatacatta aatattataa aaaatatttt
     5701 aaatagtgaa ttcttttcaa acttagtgca aggatttaca ttttgtgcgg tagtaataac
     5761 taaaagctta ggttctattg taaatactgc attaaatata gttaatatat ttgcacaaaa
     5821 ttggagtata ataaaaccta ttgtatttgg tgtagcttct gtttttatat tgtttagagg
     5881 ggttttgcta gcgactaaaa tagctacaat aggtaacgta attgcgaatg ttgctcacgc
     5941 tgcttcctct tcactatcag cacttatgac taatatacaa gcagcagcac tgatgcgttc
     6001 gaatggagct actttatcag caacaatagc cacttggggt ttaaatgcag ctttattagc
     6061 ttgtccaatc acatgggtag tattaggtat tctagcattt gtagtagtag tttttgttgc
     6121 agtagcagca gtaaacaaat tcgcaggtac aagtttaact gccttaggag taattgtggg
     6181 tgctgtattt gcagcagtgg cagcaataca aaatgttatg atttggttat taaatggctg
     6241 tatagctgta aatgaaggca ttacaaatgg ttggaatcaa tgtgtatatc taatgaaaca
     6301 agctattgca aaaggtgtaa tctttataat cgagaaaatg gcatctctaa ataattctgt
     6361 aaataatgct ggaaatgcac ttgggaaagc tttcatagat ggggcaaata tcgcaatacg
     6421 aggtgtaaac aaattaattg acctaataaa taaaatacca gggataaata ttggtaaagt
     6481 aggagaggca acgtttacgc cagttaaggc agataatagt tacatcaaac aacagattga
     6541 tagcttaaac agatgggtag gagacgcacc agagaaagta aaattggagc gaatgggata
     6601 caaagatatt ggagcagcat ttcaaaaagg aaatgcactt ggaactaaat ggcaaaatgc
     6661 tataactgat aaatttaaag atacttttga cattaataag atgctagaag atgcaaagaa
     6721 aaaattagga ttagacgatt tgtggaataa acaaaatcct ttaaacaacc ttggtggatt
     6781 tggtggagat ttaggaaaaa atgtaaagga cacggcaggc aatactgcaa agatggcaaa
     6841 gactatggat aaaagtcaag aggacttaaa atacttaaga gatatagcag agcaagaaac
     6901 aatcaatcga ttcacaggag taaacattaa aatagatatg aacaatacaa acaacataag
     6961 taaagataca gatgttgatg gaatagttaa tgtcttaact gaaaaactga acgatgctat
     7021 ggttgtatca gcggaaggaa tagtttagga aggagagtga gaaaatggct tatgattttt
     7081 acctagatgg agtacaacta ccaatcgcac cacccaagct tgaagtcaaa gtgacaaaca
     7141 agaacaagac agttgatttg ataaatactg gagaagtaaa catattaaaa aaagaaggat
     7201 tatctgaaat aagttttgaa gcagaattta cacataataa actacctttt tgtagaggtc
     7261 aatttagaga tgttcaattc tttttaagta agctagaatt actaaaaact gattgtaagc
     7321 catttcaatt tattgtatct cgtgagttag gtaacaaggt cttatttaac actaatataa
     7381 aagtatctct tgaagagtat gctatttcag aagatgcaga taatggctca gatacaaaag
     7441 ttgcaataaa attaaagcaa tatagagatt actcaactaa aaagttagtt cttgcccctc
     7501 ctaaaaatga gactggtaga cctaatgtaa agatagagcc aaaacgagtt gattcagtca
     7561 atgccacaaa cactaaaaca tatacagtaa aagcagggga tagcctttgg tcaatttgtc
     7621 agaaacaact tggtaatggt tcattatata agaaagtata cgaactaaat aaatctatga
     7681 tggataaggc aaataagggc aaaaacttaa gtaaatacac tatttataaa gggcaggtgt
     7741 taaaacttgg ttgatgaatt agtgttagca aatgatagag atgtaagatt agtaatagct
     7801 cattgggaag atttctacga acctgctgtc attgatggta tcacatggga gatagaaaga
     7861 cgaggtacac cttctaagtt agagtttaca atagtcatgg atgatatact agagttttgc
     7921 gaaggaaatt ctgtaaggct gtattataaa ggaataggca tattttatgg atatatattt
     7981 caaaagaaaa gagataaaga aaatcacatt aaaattgttg cttacgacca gttgagatat
     8041 tttaagaata aagatactta tgtatatagt aataaaactg caagtgaact tgtaaaaatc
     8101 ttggctaaag attttaattt aaaatacaat gtcatagaag atactaagta taaaatatct
     8161 agagtcgaag aaaataaaac actctttgac atgatactaa cagcactaga tgatacttta
     8221 agagagaaaa aagaaatgta taccttgtat gatgattttg gaagaataac attaaagaat
     8281 gttgcatcaa tgaaactaga tactgtcatg aacaatgatg taattgagga ttttgactat
     8341 aattcatcaa tagatagtga tacttacaca aagattaaac ttgtaagaga caacgaggag
     8401 tcaggaaaaa gggatgtata tattgctcaa gactcagctc acatgagaag ttggggaata
     8461 cttcaaatgt ttgatacagt agacaaaaac atgagtgaag cagagataaa acaaaagtgt
     8521 gatatacttc taaaactata taataagaaa actaagtcat taagtttaaa aaatgcactt
     8581 ggagatatta gagtgagagc aggttgttta gtacctgttt ttttaaatct aggagatatt
     8641 gaattgcaaa attatatgtt agttgagaaa gtaaaacata catttgaaaa taattcacat
     8701 ttcatggatt tgaccttggt tgatggagac gaatttgctt catattcttc aagctcatat
     8761 agtagtggaa atactaataa taaagatgaa aagaaaaatg gtcctgcaca aagtattatg
     8821 aaaaaaaata caggtaaaaa agttcctgct atatttactg catattatcc aggaaacaat
     8881 gcaatggaag gtggaaaaac agattgcaat ggaaagccac ttgatgtaaa atcaagaact
     8941 gttgctggtc caatgaatcg agaaggagtt aagaaaactt ggtatactga tgattttcta
     9001 aataaacatc cagtttttga atatggagat aaagtaaaaa ttatacttcc tggtactgcc
     9061 tatgacaaca aagtatatac agttaaagat aatggaggaa gaatatatgt tgaaacaaac
     9121 ggaacatatc atatagatat actattagct aatgctagtg aatgtaaaaa atttggtaga
     9181 aagaatggct atataattat aggtggagat gaagaacaaa catatcaagt tgaaggtaat
     9241 aaccaaagta atacaaataa caattctaaa gaagataaat taattagtat agcaaaaagt
     9301 aaactgggtt gtaattatgt gtatggagca gaaggtccta ataattttga ttgcagtggg
     9361 tttactcaat ggtgttataa acaaataggt ataaaaattc ctcgtactgc ttctgcacaa
     9421 agtaaagcag gaaaagcagt agatttaaaa gatagaagca agtggaaagc aggagactta
     9481 ttatgtagaa ttggtggagg aagtagtaat catgttgtaa tgtacattgg aaacaatcaa
     9541 ataattcatt caccacaaac aggagatgtg gtaaaaatag agtctgttaa ttcttataga
     9601 aaaggaaaag catacacaca tgtgagaaga tttatataag tgaggtggca atatgagcca
     9661 agatttatta cagataataa aaaaagctgc aatggatgca gtagaaacaa gcaacccaat
     9721 gagggttgta tttggaacaa tagaaagtat tagtcctcta agagttaaga tagaacaaaa
     9781 actatctatt ggtgaaattt ttctaataca aacagataca tttaaaagat atacagataa
     9841 aaaaatggga gataaattag tcttaattcg tatgcaagga gggcaacaat acttgatttt
     9901 agataggatg tgataaagtg ttaccaagtg ataatttaga ttatgatatt gaagatgtat
     9961 caataattaa ttttgatgta agacaagagc caagtaagac atttaaactt catatagaaa
    10021 agtctaagat tgatggtatt tgtgatgatg tagaagcatt aaaacaaacc atttttttaa
    10081 ttttaaatac tgaaaggtat gagcatctta tttattctag aaattatggt gttgaattaa
    10141 atgatttaat tggagaacct atttcatatg taatacccga acttgaaaga aggataacag
    10201 aagcactaat tcaagatgat aggattgaaa atatagataa ttttgagttt caaaatataa
    10261 agggtaaagt acaatgtaga ttttcagttc atacaaaata tggaaatata aaagcagaga
    10321 aggtggtgag tgtataattg tttgagttaa tgacatttga aaatataatt aaaagaatgt
    10381 tagatagtgt accagatact tttgataaaa gggaaggttc tataatatat aatgctcttg
    10441 ctcctgttgc tatagaactt acagaaacat acattgctat ggatgaatta ctagaccaaa
    10501 cattcgtaga tactgctagt tattattatt tagagaagag atgtaaagaa aggggaataa
    10561 caccacttga agccactcat acgattgcta aaggagtttt taacatagat attccacttg
    10621 attctaggtt taatctagga gaatataact atgtagcaat tgagagaata tctgaaaaaa
    10681 catataaaat gaaatgtgaa actactggac ctgtatttga gttaggaaaa ctaataccta
    10741 ttgaatatat agatggtctt gaaactgctg aactaactga aatcttgata aatggagagg
    10801 atgaagagtc agaagatagt ttaagacaaa gatattatga tagcctaaat tcacagagtt
    10861 ttggcgggaa tatacaaaac tatagggatg aagttaacaa aatacaagat gttggaggag
    10921 ttaaagttta tccaacttgg gatggaggtg ggactgttaa gttagtaata attaactcta
    10981 attttaaagt gccaagtgaa gaattagtaa acttagttca agaagaaatt gacccaattg
    11041 gacaccaagg agaaggctta ggattagcac cgattggaca ccgagtcaca gttgaaggag
    11101 ttacaagtac aactataaac atatcagcag aaataacata caaaaatggc tacacttggg
    11161 agaatataaa atcaattgca gaagaagcaa tagacgacta tttaaatgaa cttaacatga
    11221 gttgggaaga tgaagaaaac ttaatagtcc gtatatctca aattgaaact agattactta
    11281 gtattgatgg agtattagac attgcaaata caatgataaa tgatgttaaa tctaatctaa
    11341 caatagatag taacagcata gtagtgagag gtgaggtagt tggataaaga gattaatcta
    11401 ataaattact tgccacaaat tctacaagat aaagaagaat atataaaagt atttaatgta
    11461 gaaaataaag aaataaaaac actacatgat aaattaaagg acctatcaaa tgaccagttt
    11521 ttagaggacc taactataag tggtataaaa agatgggaaa agataatgtc tataactcct
    11581 aaaagtaatg agagtttaga agatagaagg tttaggattt ttagtaaata tataagtaaa
    11641 ttaccttact cagagagatt tttaaggaac tggctagata atgtagttgg agaaggcaat
    11701 tatgaattaa ctattaataa tgctacttat aacatacacc ttgagagtga tgctagaaat
    11761 caagattggt ttgaggaagt tcattctttt gtaagtaata ttaagccatg taatatgact
    11821 ttagattaca ctagagtgct tataagcaaa gacaattata tgaattttgg tataacaacc
    11881 ctaatgggtc aagaaataac tatataccct tggagtccac cagatataga aacttatgga
    11941 gaaattgatg tattaactgg caatggagtt ggataccaag agataacaat attttaggag
    12001 gtgatatatt ggctatagat aaaagttatt acactataat tacagatgta ggaaaagcaa
    12061 agatagcaaa tgcaagtgtc acaggtaata aagtagggtt tgtaaaaatt caacttggtg
    12121 atggtggagg aagtgagtat actcctactg aaagtcagac agaacttaaa aatgtggtat
    12181 gggaaggcaa catcggaaat acaaccacag atgaaactgc gccaaactgc ataatattag
    12241 agagtttaat accatcaagt gtaggtggat ttatgataag agaaatagga tatttagatg
    12301 atgaaaataa tctaattgca atctctaaat ataaagaatg ttataaacct tctatagaac
    12361 aaggagcagt tgttgatatg aaggttaaaa ctgtgcttat tgtatctaat ataaataata
    12421 tagaacttaa aattgaccct acaataattt ttgctacgct caaagatata caggatttag
    12481 atgctaaaat aagcaatgta aacactaaaa ttgatacaac taaaacagag ttaacaagca
    12541 acatagaaac tgctaagaca gagttaaaca ctagaattga cacagaaaat gagaaacaaa
    12601 atattaaaat tgaccagcta atagcaggtg gttcaaatgt tgcatctact caaacaataa
    12661 caattgatga ttggatagat aatcaagaag gtggattcaa agcaactgta acacatggtt
    12721 tattaacaca gagaataact gtaagtatta tagatgctac tacaaaagat aatgtagtac
    12781 ccgatttcac aattatagac gataattcta ttgaggttag aagtggagta aaagttgagt
    12841 taaatgttta tgtgattaat gggaatgcag agactcattt tattaatgcg actgtagatg
    12901 ataatagagt gtctgaaatg actacttatt catcaaaaaa gatacatgaa gaaattggta
    12961 aggtagcaga gcaactgaca ggaattaata gtaatattat atcgactgta aataacgaca
    13021 tactacctat atagaaagga gcgtgaaaaa atggcgttat caatgagtta ttttaattta
    13081 cctgacaaaa gaaaatatac taaaaatctt gcatttaatc catttgcagg tggaaggcaa
    13141 aattttgagt ggactggtgg tgaccatgga ctaaatggtg agtttaaaga aacttgctta
    13201 agttgcactt acaatggttc aacattaaat tggggttcag gaaatgtttg ggtcttgggg
    13261 gaatatggtc aatatacatt tacttataat tgtgaatcaa tgcatgtgga tacacaacaa
    13321 aaatttccgt atacttctaa tagaataata actataaaag gtagacctgt aatatctggt
    13381 tcagatactt cacttgggaa taaaagaaaa ggatttagtg tagattttac tgtaagtgat
    13441 gatactccaa atgttaattt aatagtacgt gcttatcttg atgataaatt aatacaaaac
    13501 attactcctg ttgtacaaaa ttcaacttta acagcaacag taacagatag tcaactaaac
    13561 tctttatccg tagatggaaa tcacaaacta aaaatacaat taaatgatgg atatgataat
    13621 tttgatagaa tttttacttt taaaaaaata gaaaagggaa ttgatatatc aacatcatta
    13681 gtaactgata gccaagctaa gtttactgta acaaaaatat acagtgaatt gacaaaaata
    13741 gagtgttatt tagatgaaac attaaaagag acttttacta cagacttgta ttcagaaaag
    13801 actataaact atgaacttat agacaatgca atacacacat taaaaatagt tgtaactgat
    13861 gcagaaaatg ttgtagaaga aaaagttata agtataagta agaatataat gccattgcaa
    13921 cctgatgcaa cattacaaga tatatcaact aagttaacag agattgggca aggcgttaga
    13981 aatggtaaaa caagcattat aaatacttta gcattaaaga atatagatgc aagtttaaat
    14041 aatacactcg ttgagttatc agagaaaatt aagggaggtt ttgatagtgg agacgctagt
    14101 ttacaagatt tgatgaatca attaacacaa gctaataata ctatatcgca gttaaatact
    14161 aagtataaag ttgctagtgg tacagttact tcttttgcgg atagtactaa aattgcttat
    14221 ccatatctaa ccgacaatgt tactaaacct ggttcttgga ttaaagttag taatttaggc
    14281 tttaaaccta atattttctt tgctgatttt gattactatg atgctgaata taaaaataat
    14341 tataaacttt tccttttcgc ttgtaatggt gttgccacac aaagaggtgt tgatttttca
    14401 agtgttacat cttttatcag aaaaagtggt gatgagtatt ttcatgctaa tggatggcta
    14461 tatagtaact cagaggggga tgtctatttt aataatactg gcgttcagat tccagcttat
    14521 aactttgatt caactcaaaa acatacttat aaatggtatg ctattaaatt tatttaaaag
    14581 gaggaaaaaa catgaatgtt ccaaaccgaa taatatatga ccaaacaggt agaacaatct
    14641 ttgaaacagg cgaatcctgt ggagatgtat tgccacatta tacaataacg gaattgcatt
    14701 atatagatat tgaatatgga agtatagatt atacaaggaa tagagttata ggtataaata
    14761 tagaaacaaa agaaccgatt ttagaagaaa taccagtata tataacagat gaggaaaaga
    14821 gaatacaaga gttagaaaat caattattaa ttgcagaaaa tgagaaagta ggaggattat
    14881 tataatgaat ataaataatg ttgtagtaag aatattagca gaaagaatat taagtaaggg
    14941 attaaatcct ctaaaaaata gagaatttca gttagatgac gtgactaaca cagagtacag
    15001 aaaagctgta gaggattata ttataaaaaa tagtggagta gtagaaggag cagaaccaac
    15061 tatatagagg gttctttttt tattgaaaga aggtgactaa atgactttta aagagttggt
    15121 taataaagtt agaaatcttg tattagaagc aaagaatgta actatagaag atacagaaag
    15181 taaatttaca agtgaaaatg tagaaggagc attgaaagaa tgtatagata gagcagatga
    15241 ggcttttcaa gaagccgata gtggaaaaac acttttatca actgctatcg gctctcctac
    15301 tacatcagaa caaacatttc aagattatgc gaactatatt acaggattta agagcaatat
    15361 aagcaattta gaaactcaat tgaaaagcaa atattctatt agatatggtc ctattgatgg
    15421 atatgatggt aatccttttt ctgctaattt tggcaagagt gcaagttacc ttattgtcta
    15481 tgtttacttt agaagaagtg tatattatta taatcccagt ggtagttctt taggaagtaa
    15541 tacaggaggt tctgaacgtg catggattac tataaacagc aataaaactg gtttttcagt
    15601 tcattcatat gatactagtt atgagtcata tccttttaca ggttattata ttgcttgttt
    15661 cgcataataa attatattat taaaactagg aggatgtatg gaagaaatta gcataaatct
    15721 actatgtgca gtagcaggag ttgtaatatc ctacttagca tttagaaata actcaaacag
    15781 aaagatacaa gatgaaacag aaacaactac aaaattagaa caacaaataa cttttttatg
    15841 tgagaatgta agagatataa agcatgatgt agcaaagttt aatactagtt tcttagatat
    15901 tagtgaacga gttgcaaaaa tagaagcaag tacaaaacaa gcacatctta gaattgatga
    15961 aattgtaaat agaattggag gaaaataaga gatggataat ttaataagtt ttataccaga
    16021 gcagttgcta attttagtag ctgctctctc tattataggt aaaggttgta aaaaatataa
    16081 acaattagat aataaataca ttccagtagt gttactgata cttggaatag gtttctcaat
    16141 atggatgcta ggattaaatc ctgttgcagt cttacaaggt gtaatttgtt ggggagttgc
    16201 aataggtata aatcaaactt acaaacagtt gaaggatggt gaaaagtaat gaaattaaca
    16261 aaaatattat tactcacaaa aatttaaaaa atttcattaa atagagtata cttttatagc
    16321 taataagtat ataataatag tacagaactc gtaaagcatt tatatgctca aatatacggg
    16381 acattgattt ttgaaggaac ccgccaagct tcttttatag ctcaaatagg cgggacagat
    16441 aaatttaccc actaatatta attggtgggt tttattatat aaaagtatat ctatgaaaag
    16501 gtgaaaacaa tggttgaagt aaaagaagaa aaaacatttg atgaacaaat agatatttta
    16561 aaaagtagag gattaataat aaatgataaa gaagatgcta aatttgtatt aagtaatgtc
    16621 aattattata ggtttacagc atatcttcta agttttaaga atgatgatgg ctcatataaa
    16681 gaaggaacta cgtttgaaga agtttatgat atatataggt ttaataagga atttaggata
    16741 ttattaacag atttgttagg gagcatagaa atagcattta ggacatacat tgcatataca
    16801 ttagcaatta aacatggtgc ttgtggatat ctagaaaggg agagtttcaa agatgaaaaa
    16861 ttctatatta attttttgac agcattagag agagaaaaaa gtaataattc agataagctt
    16921 tttattatac accataaaga aaaatatgaa ggaaaacttc ccatttgggt tgcaacggaa
    16981 ataatgactt ttggtatgtt gtcaaaatta tattcaaaca tgttgccaga agatactaga
    17041 tacataaaaa ataatttgtg tagagtgaat actttattag ttaaatcttg gttacaatca
    17101 ttaacacagg tcagaaatca atgcgctcat tatggtagaa tatataataa taatttccgt
    17161 attataacaa taaaaaacga atataaaaag tataacttgg ataataaaaa gatattttct
    17221 tatatacttg ctatgaagca tttgactatg gataaattaa tttggaatag tttttttata
    17281 aaacttcaaa agttaattaa tgattataat aattctatag acttaaagct tattggtttt
    17341 cctaataatt ggatagagat attggctaaa taaaatagtt actttaagaa gtttataaac
    17401 acttactata tgtaagtgtt tttttattga aaagaaggag gaaaataaat aatgaaaata
    17461 tgtattacag taggacacag tattttaaaa agtggtgcat gcacttctgc tgatggagta
    17521 gttaacgaat accaatacaa taaatctctt gcaccagtat tagcagatac atttagaaaa
    17581 gagggtcata aggcagatgt aataatatgt cctgaaaagc agtttaaaac taaagcagaa
    17641 gaaaagactt ataaaatacc tagagttaat agtggaggat atgatttact tatagaacta
    17701 catctaaatg caagtgatgg tcaaggaaaa ggttcagaag ttctatatta tagtaataaa
    17761 ggtttagagt atgcaactag aatatgtaat aagctaggta cagtatttag aaatagaaga
    17821 gctaaattag ataaaggatt atatatctta aatagttcaa atcctacagc agtattaatt
    17881 gaaagtttct tctgtgataa taaagaagat tatgagaaag ctaagaaact aggtcatgaa
    17941 ggtattgcta agttaattgt agaaggtgta ttaaataaaa atataaataa tgagggagtt
    18001 aaacagatgt acaaacatac aattgtttat gatggagaag ttgacaaaat ctctgcaact
    18061 gtagttggtt ggggttataa tgatgggaaa atactgatat gtgatataaa agattacgtg
    18121 ccaggtcaga cgcaaaatct ttatgtcatt ggtggtgcag catgtgagaa gattggttct
    18181 atgactaaag aaaaatttac tatgataaag ggtaatgata gatttgatac actttataag
    18241 gcattagatt ttattaatag atagattata taaaatattt tagtatttct tgaaaatcat
    18301 aagtatggta atatttagat aaatattatt tattattaat aggtatgggg ggagattatg
    18361 atatttaaga agtatataaa atcattactg atagttgtta gtgttacatt gataatgaac
    18421 aaatcaatat tatttgtaaa tgcattagat ttagagagta acaataacat aaaatcttat
    18481 aaaagaaaga atgtaaagga aattgatata agcaataaat ttgttgatga atcctttaga
    18541 agagatattg ttgaaaaggt attagataat agggatgatc cattaacaaa tgaagttgca
    18601 tcaaaagata actataaaat atatgaaagt gatttaaata aaattgagag ttgcttagag
    18661 ttagatttac ataaaaatcc agatgtttct aatccaaaca aaatagataa tttagatggg
    18721 atagaaaatt ttagaaatct agaaaagctt gattgtagtt caaataatct agaaagtgta
    18781 gatttaagta aaaatataaa attaaaatat ctagatatta gtggaaataa aatattaaac
    18841 attgatttaa aaaacaataa tcttattaat gaattacatt gtgatgcaaa taaattatca
    18901 aatttagacc ttaaaaataa taaaaatttg gtaagtttat tttttactag taatgaatta
    18961 acagagatag atttaagtaa taatgtgaac ttagaaaatt tacaatttct taataataat
    19021 ttaaaaagta tagatttaag tcataataaa aagttgaaat ctctaaattg tactaacaat
    19081 aaacttaaat cccttgattt aagtaataat gtttttttga aaaatttaag ttgttcaggt
    19141 aataacctga gtaaattaaa tataaaagga cttacaagtc ttgagtattt gggatgtgct
    19201 aagaataaat tacaagattt agatgtatct acaaatataa aattagattc tttactttgt
    19261 gggaaaaata gtttaacaaa aatagatata agtaaaaata aagaattaaa ttcactggaa
    19321 tgtagtggtc aatatataga aaaaagcatt ataaaaaatg gtgaaaatat agttgtagat
    19381 ataggaattg aaaattcgaa attaaaggaa ttatatccac aaaattataa tatttcaaca
    19441 ggttttctaa catgggaaaa tctttctgac tttccaaata gcataagtta tagtttggaa
    19501 tatgaatatg gtccagtaaa tgatacagag actatggatg taaatatatc aatagataaa
    19561 ttagtgaaat gtagaatcag atatatagat tatgatggaa gtataattaa tgaaaaagaa
    19621 atatcagata attctagtat aaatgaaatt caaattaatc ctcaaagaga aaactatgag
    19681 tttagtggtt ggaggaacaa taaagatgaa aaaatatata catcagagca ggtaagtaaa
    19741 ttagtttttg atgatagtac tgattttata gcaacttata aaagaaaatc aacaggatca
    19801 agtggttctt ctggtggaac ttcaagtaaa gaagatttta atatagcacc atctaaggaa
    19861 aaaataacag gtgcagacag aaatgaaaca tcagtgaaaa taagtcaaaa aggatggaat
    19921 aaagctgata atatagtgtt aataaatgac tctagcatat cggatgcttt atcagcaaca
    19981 ccatttgcta agtctaaaga tgcaccaata ttacttacta aaaataataa tttaaataaa
    20041 ttaacagaaa aagaaataaa tagattagaa gcaaaaaatg tgtacatagt gggtggatta
    20101 aagtctgttg atgaaaaagt agtgtctgat ttaaagaaaa aaggattaaa tgtaattaga
    20161 atatctggaa atgatagata tgaaacatca ataaaacttg caaaagaatt agacaaaaat
    20221 tctaacctgt caaaagtagt agtggtaaat ggagaaaagg gactagctga tgcagtaagt
    20281 atgggagcta tatcagcaaa agaggaaatg ccaattcttc ttactaatca aaatgatgat
    20341 atgaaagata taaaagactt aatagctaat aaaaacatat caaaatcata tgtaataggt
    20401 ggagaatctt tatttaataa taaagaagtg aataatacat taccatctgt aactaaaata
    20461 gcaggttctg atagaacaga aactaactca aaagtaataa gtcatttcta tagcaaagat
    20521 acacttaatg acttatatgt agctaagaat ggaatgaata aacaagacga tttagtagat
    20581 gccttatcag taggagtgct tgcaggtaaa actgaatctc cagtagtatt agttggaaat
    20641 ggattagatg atagccaaaa agagttaatc aagaataaaa agtttaaaaa tataactcaa
    20701 attggtggaa atggaaatga aaaagcattt aatgaagtag aaaacttagt taaatagatt
    20761 gaaaggtagt aactggaaat agttactacc tcctttttta ttcattttca gttttttcaa
    20821 taattatttt tccatcctca aaagtaacaa gaacatccct ttcatcagga gagatattca
    20881 tctctttaat ccatgacatt ggaagtatca atctgggtgt aaaagagcct ttgccacttt
    20941 tattaaatcc aattctaagt tttctttgct ccaataatat cattcctttc tactattaat
    21001 aaatgccagc aataataaag taaataccaa agcaataaga gctttaaaag taaaacttat
    21061 tattatatta ataatattta aaactatagt gataccaaga ataatcatac aaattctata
    21121 aaatttatta ttcatattaa attagaaaat gtgttataat attagaaaga agctacctag
    21181 aaggaaggta ttttcctcct aggattgaaa cttataattc tttaatcaat cttagtattg
    21241 cgagtactag attaattaaa actaatgtga aagagaaagc atttttaatt ttattaaatt
    21301 tgttttctct tttatttttt cttctttcta atctccccac tttcttacct cctttctata
    21361 tttatattat atcatcacgt gacgtgaaag tcaataaata ttacatattt ttcaataaag
    21421 ttatattgat aaactatatt ttttacaaat aaaaataaat ggtgacaaaa ccaaacttgc
    21481 caccattttg ccaccgaaaa taaataatag aataaattta aattaaacat aataaaacat
    21541 aaacaacaaa actgacctta ataaaacatt gaaataccaa cacttgtaaa aaataacaac
    21601 aataaacaaa taacctagaa taatattaca acttaagtaa ataataattt tgaataataa
    21661 tttacggagg tattcatatg tttaaacacg ataaagcatt attaaaagaa gtaaaagtag
    21721 aaagaccaaa tcctcaatat gctgttttaa tgcaagaaca gttgggtggt gcaaatggag
    21781 agttaaaagc agctatgcaa tacttgtccc aaagttttag aataaaagac cctcaaataa
    21841 aagatttatt tcttgatata gcagcagaag agcttagcca tatggaaatg gtagcacaaa
    21901 ctataaattt attaaatgga catgatgttg attataatgc agttaataca ggcgaaatag
    21961 aaacacatgt attaactggt ctatcaccag tcttaataaa ctcatcagga gctccttgga
    22021 ctgctaatta tgttacagtt acaggggatt tagtagctga cttactttca aatatagctt
    22081 ctgaacaaag agctaaggta gtttatgagt acttgtatag acaaatagat gataaatatg
    22141 taaaagaaac aatagatttc ttacttaaca gagaagaagc acataatgct ctatttagag
    22201 atgctttaaa taaagttaaa gatacaggtt caaatagaga ttttggagtt acagaagatt
    22261 ctagattata tttcgatttg tctactccag ggccaaatca caatactaag atagatatta
    22321 atcctccttc ttttgaaaaa cctttaaaaa aataatttga tattttttat gttgttttgt
    22381 tttagtagtt ataaaaatta tttactagaa gaattaatta tatgaaaaat taaatatgta
    22441 tagttaaaaa tgggtataca cttattataa gtgtatatct atttgtttat tgcaaaacat
    22501 ataataaaat aacaaatgag gtggtatttt ggacagtaat agaaaaccta ataatctaat
    22561 aaatgaaaaa tctccatatc ttttacagca tgcttataat cctataaact ggtatagttg
    22621 gaatgatgag gcttttaaaa aagcaaaaga agaggataaa ccaatatttt taagtgtagg
    22681 atattcaaca tgtcattggt gtcatgttat ggaaaaagaa tcttttgaag atgaagaagt
    22741 tgctgaaata atgaatagaa actttgtggc aataaaagta gataaagagg aaagacctga
    22801 tgtagatagc gtgtatatga cagtttgcca agctatgaca ggtagtggtg gatggccaat
    22861 gaccataata atgacaccag ataaaaaacc tttttttgcg ggaacatatt tcccaaaata
    22921 ttcaaggtat aatagacctg gagttataga tttattaaag aatgtatctg aaaaatggaa
    22981 tacaagtagg gatatattaa taaaatctgg agatgaaata atagaagctc ttaaggatga
    23041 ttttggtgta aaaaatactg agggtgattt atcaaaagag atgttgagtt catcagttag
    23101 agtatttaag gccatttatg atgaaaagta tggtggtttt ggtaatgctc ctaaatttcc
    23161 aagtcctcag aatcttatgt ttttaatgaa atattatagc atagaaaaag ataaagatgt
    23221 gttaaaaatg gtggaaaaaa ctttagatgg aatgtataga ggaggcttgt ttgatcatat
    23281 tggatttggg ttttcaagat actctactga taaaaagtgg ttggctcctc attttgaaaa
    23341 aatgctatat gataatgcta tgcttactat agctttttta gatgcatata aaataacaaa
    23401 gaaagagtta tataaagaaa ttgctataaa aactatagat tatgtagtta gagagatgaa
    23461 ggataaagaa ggtgggtttt attcagcaca ggatgctgat agtgaaggtg aagaaggtaa
    23521 attttataca tttaatcctc ttgagataat tgaagttttg ggtgaagaag atggaacttt
    23581 ctttaataat tattttgata taactagtag tggaaatttt gaaggtaaaa gtattcctaa
    23641 tcttataaaa aataaagaat atgaaagaca taatgaaaag atagctgacc ttagtaaaaa
    23701 ggtatttgaa tatagaaaag aaagaacatc tttgcataaa gatgacaaga tacttacatc
    23761 atggaatgca ttgatgatag ttgctttaac aaaggcatat agtactttaa aaaatgacat
    23821 atatttagag tattcaaata agtgtcttaa ctttataaat aataatcttg taaatgagtc
    23881 aggtagatta ttagctagat atagagatgg aagttccgac tatttagcat atttagatga
    23941 ttatgctttt ttaatctggg cgtatataga gctttatgag tcaacattta atatgaaata
    24001 tttagaaaag gctttaaatt tgaatgaaag ctgtatcaac cttttttggg attatgaaaa
    24061 aagtggattt tatatatatg gtaaagatag tgaaaattta atagcaagac caaaagattt
    24121 gtatgatgga gctattccat caggaaattc tgttcaatta tacaatctta taagacttgc
    24181 gaaaattact ggagataata gacttgaaga aatgtcatat aaacaattaa aactgtatgt
    24241 ggataatgta aagagttctc caactggcta cagcttttat atgctttcat tgatgtttga
    24301 actttattct actaaggaaa ttatatgtat ttttaaggaa gattctgatt taattgcatt
    24361 taaagaattg ataagtgaaa attttatacc aaatgcaact tttttagcaa agaaatacaa
    24421 tgaagaaaac actattatag gttttttaaa taactataga ttgaaggatg ataagactag
    24481 ttattacgtg tgtcaaagta atagttgtag tcaaccaatt aatgatttac aaaaattaaa
    24541 agatatgatt ttaggagtag aataatcata atagcgaaaa aggagatgct ttaaaataaa
    24601 agtctaatca tctccttttt ttgtacaaaa aacagaaaaa gagttcctaa gaacacctaa
    24661 tctatgtaat gattgttttg ttaaaaaata aaaatgacat tatagttata taaaatattg
    24721 tactataaaa aagtggtatt atagatgcga tagtattaat cgtttttatt taccctattt
    24781 cttctttttg caaattcttc aagtgcttca gatttaattt tatctatttc ttcatattcc
    24841 ataaaattag catcttcttc aaagccatct tgttcttcac cattaaaacg atacattttt
    24901 tttagtaaac tccataaggt ctctaattca tctttggtaa attcgtgaaa tacatctgcc
    24961 ataaagttta ttccagtcct actacatgtt accataacct tttttcctaa gtctgtaact
    25021 ttaacattaa ttgctctctt atcatgagga cttggaatta catcaacata tccatttttt
    25081 tcaagattag caactagtct atttatattt tgtttacttg tacccatttt tcttgcaata
    25141 ttatttaatg ttgtttcttc ctctggtaaa tgaagaattg ataaaatagt catatactgt
    25201 cttgaagtaa gtataccaaa atatttatct ccttctattt gtattttgtt tgtaagggta
    25261 aaaagagttg catatgtttg attcattaaa aagagctctt ttagttcatt tgaataatcc
    25321 atgaaatata tctcctttat ttttagaagt tgttttgtcg aaaacagaat atcatgaatt
    25381 aattctaatg tcaatatggt gtcaaaatat attaaagtat tactttttta tgtaactatt
    25441 aattaaatta ttgtataatt gtatgtaaaa acttctatgt accaatgata atttctatga
    25501 ggaattaata attcttaaat tttttagaaa gattttgact tgaaaatact tgtaatataa
    25561 tatataaatt aatatactga ataaaatcaa tctggaggga taattatgaa gtgtacaaac
    25621 tttactttca aaggagagga aggtttagat atatatacat ataaatggga agatgaaaat
    25681 ataaaaaaac caaaggcagt tatccaaatt gcacatggaa tggctgaaac tgcacaaagg
    25741 tatgagactt ttgccaaggt acttactaaa aatggttata tagtatatat caatgaccat
    25801 agaggtcatg gaaaaactgc aaagataata gaaaatgttg gacatttagc tgaaaaagaa
    25861 ggatttagat gtcttgtaga ggacatgtat actttaacaa atattataaa gaaagaaaat
    25921 gaagatttgc caatttatct atttggacac agcatgggtt catttgcaag tcaaagatat
    25981 ataatggatt acagtaataa tttatctggt cttatactat gtggttcaaa tggaaagcaa
    26041 ggaatcattc taaatcttgc tcatctgata atcaatcgtg agattaaaaa gtatggaaga
    26101 cgttctaaaa gtaataaaat aaataatttg attaaaaaat agctatgcac acttgtgact
    26161 ttagtcatga gttagtagct aaaatagtca gcatataggg aaacctatat gtagagatag
    26221 gatagaacct atccaatact acttgaattg ctggaaacc
//
LOCUS       DAMJYN010000053        24589 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.054, whole genome shotgun sequence.
ACCESSION   DAMJYN010000053 DAMJYN010000000
VERSION     DAMJYN010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 24589)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24589)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24589
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.054"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(470..646)
                     /locus_tag="PC466_002378"
     CDS             complement(470..646)
                     /locus_tag="PC466_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769747.1"
                     /translation="MFIGEIDKCTHILTAYISSSYDYCNFLDTQLDDFISEYGETVVE
                     TCLHQVLLLVSRYN"
     gene            1221..2243
                     /locus_tag="PC466_002379"
     CDS             1221..2243
                     /locus_tag="PC466_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769748.1"
                     /translation="MVNWEIKKLAKSKSMFISLGILVLILMISIFITPVLETERYYID
                     KEKGCIEDTRSGIDIGNEKFQNKINVLKQFSNQTDTGEFSKKIELMSKKKLDNLSVNE
                     YKDISFWKVFNYRVTNSLINVGMLIIISIIISNIYVDEVVTSVKDIILSSKEKKKALK
                     SKIFVALLVPLVIYSVYLMGIFIITCMQQGVPVNGDLESFRIVDNVVALKTNLSITKY
                     VILNIGIELLMFEGWAMIAIFGSFISKSSISSISFFIFIISITKIMSVIHILPKKLLS
                     VVSNVNYYDLIFGFNKIIGNYLGDIMIFKVNIDIVNIAIGLLMAILIGAMSLCFLVIK
                     SDYISR"
     gene            2257..3144
                     /locus_tag="PC466_002380"
     CDS             2257..3144
                     /locus_tag="PC466_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011948651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2769749.1"
                     /translation="MNKLEIENLSKIYGKKVANDKITVTLENGVYGLLGPNGAGKSTL
                     MKQITTLIKPDEGQILYNGEDIFKMDANYRNILGYLPQEFGVYKNFTAKEFLQYIGAL
                     KGLRGKYLNSKIGELLDLVGLYDVRNKSIGKFSGGMKRRVGIAQVLLNDPKIIVFDEP
                     TAGIDPQERARFRNLIAKMSRDKIIILSTHIISDIESVAKETIMIKDGKLLMKGTHKD
                     ILSHMENKVYNVQVKNECEVDDIQSKYKVVSIQSDIDSVVLRIVSEDIPSGDNIQPVQ
                     AKFEDVYMFYFDLEDAREV"
     gene            3150..3923
                     /locus_tag="PC466_002381"
     CDS             3150..3923
                     /locus_tag="PC466_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2769750.1"
                     /translation="MMYLVKAEMIKILKSKSVWIIWLFLIFLGFLLIRKFDVLDTYAD
                     IFYKIEGSIPLIGLIMFIITSGNYIKEYDSNMTGLINTTKKGKKSVVLSKLVANGLIL
                     SIINISFILLVGIRGFSFFDFKNLNEPIHNLWYFGNSNLNLTVIQMYIIVILTTIFAS
                     FIFAQIGLTLSSIFKSAVIPFILGGLIMAIPYFSVGFIPDKAIKFMSVTPNWIMMSQQ
                     MVRYNVPSILIVFSIVISIILMIVLTKITYENFTSSKRF"
     gene            4035..4760
                     /locus_tag="PC466_002382"
     CDS             4035..4760
                     /locus_tag="PC466_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012450879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2769751.1"
                     /translation="MENRVLIIDDEVEILKLLETVLKKEGLNNIYTAKTKKEGLELFK
                     SINPDLIVLDIMLPDGEGYDICKEIRKTSNSPIIFLSAKTEELDKLLGLAIGGDDYVT
                     KPFSPKEVAFRVKAHLRRLSYFSDVQNESKNLNKNEEKIISFGPYILNESRAELIKDG
                     KSIGLSAKELKILSLFAHNQNQIISKEKLWDKVWGEDYVGFDNTIMVHIRKIREKLED
                     NPSKPEYILTIKGLGYKLAVKED"
     gene            4764..6167
                     /locus_tag="PC466_002383"
     CDS             4764..6167
                     /locus_tag="PC466_002383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2769752.1"
                     /translation="MKWKITRNFIFTIVFVAISVVIINIISILYVISTNSFFKVVDSG
                     NNPEEFARSFEKDLYEKDGEFKLSKIGAEKLEKSNSWIQVLNDLGEEVYGVNVPKDTP
                     KKYTPFQMVNNYKYIETKYVNFVLEKYLNKKHLNIIVGIPSRDISRIILTYSQNNIKK
                     TLNKVIIITLVIDSVVALGVGYLFSRKLTKPISSVLWSIETMANGNYSLYLKDRGIYE
                     EVFKNINMLADTLRVNEVERKENEELREEWLANITHDIKTPLASIQGYAEIINDKDYE
                     FEEDEIREYTEIIYNKSKYIKDLVDDLNLSTRLKNNTIVLDKKKINLVSLVRDIIIDI
                     LNDNRYKNRNIEFESNEDLIEVYVDSILFRRAITNLIFNSIVHNSEGTLISVEIVKKD
                     NIEIIIKDNGIGISKSDLKHIFKKYYRGTNTGEMHKGSGLGMAISKEIIEIHKGKIYV
                     SSEIGIGTKIIIEIKQN"
     gene            6178..7002
                     /locus_tag="PC466_002384"
     CDS             6178..7002
                     /locus_tag="PC466_002384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraX"
                     /protein_id="HDF2769753.1"
                     /translation="MDFFKKGISGFTIKILALIFMTFDHIAAFMPQTMQIPIWFHWVG
                     RISAPLFIFMAVEGFYHTSNRKKYISRLYIWSVIMAIGNQIINNVFSHPEGAIIINNI
                     FSTLFLIAIYLQAIEFIKKFRKEKEIKYFIIGLLMIIIPIILGIFTVALLFKVTNRVI
                     TLFMILVPVPFLVEGGPIWIILGIIFYLCRGKKFSLSICYVLMCIFIFTTMSNGDYSL
                     KNSILQNYQWMMIASLPLMLLYNGEKGKSMKYLFYLYYPIHVYILYILGIYLINGF"
     gene            complement(7327..7947)
                     /locus_tag="PC466_002385"
     CDS             complement(7327..7947)
                     /locus_tag="PC466_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HDF2769754.1"
                     /translation="MKVLLINGSPNQYGCTYTALNEITKVLSKHDIKTEILYLGKEAI
                     PGCISCASCFETGKCIRNDKVNELIEDLDNIDGIIIGSPVYFSSATGQLTSFLDRLFF
                     IAGSRMATKLGASVVSCRRGGASATFDQLNKYFSISNMPIVSSQYWNQVHGFTPEDVM
                     KDEEGLQTMRTLGENMAWLLKCISAGKKAGIKEPQYEETIMTNFIK"
     gene            8213..8545
                     /locus_tag="PC466_002386"
     CDS             8213..8545
                     /locus_tag="PC466_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2769755.1"
                     /translation="MSIDCISNTDLSETGFSYTLSLISGKYKMIILYCLVEFEVVRYN
                     ALKRYINTISYKTLSLSLKELEADNLIIRTEYPQIPPKVEYSLSERGKSLIPILDAMC
                     EWGERNRP"
     gene            complement(8664..9305)
                     /gene="pcp"
                     /locus_tag="PC466_002387"
     CDS             complement(8664..9305)
                     /gene="pcp"
                     /locus_tag="PC466_002387"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HDF2769756.1"
                     /translation="MKILLTGFDPFGGELINPAQEAVERVNNNINGAEIIKITIPTVM
                     TKSVEAIDKAIQEHNPDIVISVGQAGGRFDITPERVAINIDDFRIKDNEGNQVIDTII
                     KEDGEPAYFSKLPVKAMVKHMNENKIPASVSNTAGTFVCNHVMYGILYMIDKKYPNIK
                     GGFIHIPYTTSQVINKKNTPFMSLEEIVKGLELAIEACIIYKEDVKEIGGEIS"
     gene            complement(9326..10258)
                     /locus_tag="PC466_002388"
     CDS             complement(9326..10258)
                     /locus_tag="PC466_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HDF2769757.1"
                     /translation="MQNFINISLEIFYALMGFLMIVIAYKSFTTINNNKKYGTSLFWI
                     LISLPFIFGRLIPANIIGIILILSSLLTLSKQVVFAKYEEPDENFGKEQADKLKNKIF
                     IPSLILAFAAVVVAMSLSNFDNSSQFAIGVGSIIALISALIITKAKPATSVQDGSRLL
                     QQMGPASMLPQLLVALGALFTQAGVGEVISTMISGVVPADSRLFGVIAYVLGMVIFTM
                     IMGNAFAAFSVITAGIGIPFVLSQGGNPAIIGALALTAGYCGTLLTPMAANFNIVPAA
                     LLECKNDYIVIKYQAPVALVLIIAHILVMYFLGF"
     gene            complement(10280..10945)
                     /locus_tag="PC466_002389"
     CDS             complement(10280..10945)
                     /locus_tag="PC466_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HDF2769758.1"
                     /translation="MIKLIGILIVVIGFILKIDTLFTVLLAGVATGIVAGLDFNQIFT
                     ILGDSFVSNRGVSLFILTLPVIGVLERYGLKQRAVSLIEKLKRLTTGKVLTIYMIARQ
                     IAGALSIRMSGHPQFVRPLVNPMAQAAGLSNSDELKESDEEAIKALSAASENYGNFYG
                     QNLFAGSSGVLLIASTLTQFGYNVTGLNIVKASTIMAVIALVVATIQFTLYDKKLNKS
                     HKK"
     gene            complement(11492..11965)
                     /locus_tag="PC466_002390"
     CDS             complement(11492..11965)
                     /locus_tag="PC466_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HDF2769759.1"
                     /translation="MNTIIIYSSKYGCTKDCANILKNKLSDNVTIVDINNNNKIELSK
                     FDKIIIGSSIYVGSVSKKIQVLCNDNVELLNKKQVGIFLCCGFSEQADKYLKSNFPSS
                     LLESANAIGIFGSEARLEKMKFLDKLIMKAVSKGNYDSFRISQDNIDNFLINLNS"
     gene            complement(11968..12372)
                     /locus_tag="PC466_002391"
     CDS             complement(11968..12372)
                     /locus_tag="PC466_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein"
                     /protein_id="HDF2769760.1"
                     /translation="MKIRNKATNKKKKYVKISIALFFVFICIIIVIVSNLKPENLVVK
                     DIDINNVKNGIYTGSADNNLVKATVSVEVNNGKIQNINILKHDHLLGKPAEKITTSII
                     KQQSLDVDAITSATYSSNTIRKAVENALRKGE"
     gene            complement(12347..12976)
                     /locus_tag="PC466_002392"
     CDS             complement(12347..12976)
                     /locus_tag="PC466_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2769761.1"
                     /translation="MSIKERRKNEKEEMKKKIMDASIEIINQHGYENLSIRKIATKIE
                     YSPTTIYLYYKDKAEIISDMTNKLYNTVESNAIDIMNNCSSLPIDKQIIEIMTSFIKT
                     LSSEPEMAKAIMHSRMNIIFASENTNNTPSNNGIKMLDKFLSIGIEQGIFKKNIDKSS
                     WMLISALLGFVLCVVENKLYSLHNFSQLIENFLDILVGGLYNENSQQSY"
     regulatory      13341..13384
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            13485..14453
                     /locus_tag="PC466_002393"
     CDS             13485..14453
                     /locus_tag="PC466_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside hydrolase"
                     /protein_id="HDF2769762.1"
                     /translation="MEKRKVIIDCDPGIDDSLAILLALNSPELEVIGITTCCGNVPAN
                     IGAENALKTLQMCSSLNIPVYIGEEAPLKRKLVTAQDTHGEDGIGENFYQKVVGAKAK
                     NGAVDFIINTLHNHEKVSIIALAPLTNIAKALIKDKKAFENLDEFVSMGGAFRIHGNC
                     SPVAEFNYWVDPHGADYVYKNLSKKIHMVGLDVTRKIVLTPNIIEFINRLDKKMAKYI
                     TEITRFYIDFHWEQEGIIGCVINDPLAVAYFIDRSICKGFESYVEVVEDGIAMGQSIV
                     DSFNFYKKNPNAIVLNEVDEKKFMYMFLKRLFKGYEDIIDSVEGVI"
     gene            14455..15018
                     /locus_tag="PC466_002394"
     CDS             14455..15018
                     /locus_tag="PC466_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HDF2769763.1"
                     /translation="MKRKICVKTITLIAFGISINIIGAFIAMGLRLPVYLDSIGTIMI
                     ASLLGPKYAVVTGVFGSLISGITFDVYSLYFAPVQISTGLLAGIAFKKNFLRGLKTPL
                     GVLLFAIPTSIISSIISAFLFGGMTSSGSSYIVQILKVLGLGDVFSVFVTQVFTDYGD
                     KLLAVVLVNLGLNAVPKTLKVSLTGGK"
     gene            15026..15715
                     /locus_tag="PC466_002395"
     CDS             15026..15715
                     /locus_tag="PC466_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HDF2769764.1"
                     /translation="MDRYSEITNKNQREIVLLKGFPCIWGKCSFCDYIDDNSNLEEEM
                     NKLNLRVLKNVTGKYGVLEVINSGSCFELPKDTLEKIKCIIKEKNIKKLFLESHWSYK
                     NRLKEMREYFEIPVVFKIGVETFDNDFRNNILNKNANFKTPQDVKEYFDSPCIMIGIK
                     GQTKEMIDKDIEIILNTFEKATVNVFINNSSSIKRDEELVKWFVSKYKFLDENPNIEV
                     LYNNTDFGVGD"
     gene            15842..16570
                     /locus_tag="PC466_002396"
     CDS             15842..16570
                     /locus_tag="PC466_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HDF2769765.1"
                     /translation="MMFDRGKWNKLDYNELLEYMMSIKDIKYRDFNKKLIPGTENIIG
                     IRVPNLRKLSKEISQGNWKEFLEVAEDTYYEEVRLQGMVIGNINSNFEETLYYVKRFI
                     PKIDNWSVCDGFCSGLKSMKKYKENMYDILKKYVYSKNPWEIRFALVMFLIYYVDDKH
                     IKEIFEYCNNIQSEEYYVKMGMAWLLSICFIKCEEETFLYIKNNNLDDFTYNKMLQKI
                     IESNRVDLEKKNIIRSMKRKTRRC"
     gene            16584..17258
                     /locus_tag="PC466_002397"
     CDS             16584..17258
                     /locus_tag="PC466_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HDF2769766.1"
                     /translation="MNNNEDRIDKFLELQSKGFKFAEIAQNLKISQSTLRTFLNKKGY
                     KSEKGKYILKDELNYNKSLDNRNLEEEKAKEYEKSKKNTISNRKKVSTKKKISNEKAL
                     SKSVEQIEFNDTGLKNAKRKQNVKPKKDRKINITQEDLDKLCEVYDWYLEVKDYNIKP
                     KKVSNKKDVHIDDEHIDELKTTRIRIDKEIWNDFERLCSNSNFEKHQILTQALKEFMK
                     KYKNLL"
     gene            17284..18120
                     /locus_tag="PC466_002398"
     CDS             17284..18120
                     /locus_tag="PC466_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769767.1"
                     /translation="MNKIVKKSISLMIILTIFIFMLTACEKDEQPDSVDIQTEDKNEI
                     KIDEGNAKVLNIGKSEIINIDEGDKVDTSTKVENNSTFNISNVELIYNEYDENKKIIS
                     SDSKALLDMTLMPGKVAYIECGHKTFVKGVEVYAYEYEAEGKIVYVNLKENTINIRNN
                     NIKLENSSQYEVLSTSELKKVNESNEGITYQVKVKNSSSKDLGNIILKTAEVNENGEY
                     LTVNRVPSYKILKPSEETDIDILCSTKAKSVEIVGYTYDDIKEKANVDIDLKSHKVKI
                     DK"
     gene            18136..18807
                     /locus_tag="PC466_002399"
     CDS             18136..18807
                     /locus_tag="PC466_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2769768.1"
                     /translation="MKVLIVEDNKILLESVVEELSKHFETEKCEDGEEALYLVNQNIY
                     DLVILDLMLPNINGFDILKKMRVNNIDTPVLILTAKETLDDKVEAFTIGANDYLTKPF
                     YMEELVARVYAILRTNGKIKERNGLEFKSLYLDTLEKRVYIEKEEIKLQNKQFNLLEY
                     FVLNKGSILLKEQIYDRIWGIDSDATIEIVEVYVSNLRKKLSKYGYDKYIKTKRKVGY
                     IFDDK"
     gene            18797..20029
                     /locus_tag="PC466_002400"
     CDS             18797..20029
                     /locus_tag="PC466_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2769769.1"
                     /translation="MINKNVFTSTKNHLIKMYIIVVGSFLIIFSIFIYSYFRGLTYSG
                     IDSEINDELEYIVSQFKRTSFLNPIRLKDPKDMVYVYEDGRISYYTQNEYFDELLPDR
                     RLDKKNSFFKYTENGYTFRELNVDVGRYQIQIIRNIDSEMNSLRQLTSVLIIGILISV
                     IITYFVAVYLTRKALIPIETAWKNQAKFIQDASHELRTPITIVSSKLESMLKSPESTV
                     NDEVETIATAMKETRRLKKMITDLLSLTKEDSIVKVNLEEIDLEKLLEEISEDYIDIA
                     EFQEKRFVFNSKLKNKVIITDKNKLRQLILIFIDNAFKYTKLGDEIALELKEDIEDEV
                     TLLISDTGIGIKKEEIPLIFDRFFRSENVRNKDLEGSGIGLSIARMISLNLSIDINVT
                     SDVDIGTTFELSIPKKLK"
     gene            20179..20496
                     /gene="trxA"
                     /locus_tag="PC466_002401"
     CDS             20179..20496
                     /gene="trxA"
                     /locus_tag="PC466_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HDF2769770.1"
                     /translation="MAKVINTSEFRSSVEGSKGVVVVDFFATWCGPCNMLGPVFAELG
                     EEMKDKARFVKVDIDESLEIAQQFNVSTVPTMIIFKDGKPVETLIGFMPKNKIEMQVK
                     SYL"
     gene            20513..21391
                     /locus_tag="PC466_002402"
     CDS             20513..21391
                     /locus_tag="PC466_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDF2769771.1"
                     /translation="MRYDIAIIGSGPAGLSAAINAKIRNKTIIMFGNDNLSNKLVKAP
                     SIDNYLGFYDISGDELKDKFKSHIDSMDISIENKRINNIYAMGEYFTIMSGNDMYEAT
                     TVILATGVEYTRPIKGEEEFLGRGVGYCATCDAPLYRNKKVAVIGYNEESKEEANFLS
                     ELTSKTYFIPMYKKDNLMRSSDNLDDSIEVIHDRPVQIDGDKLVNKVSFKENHIEVDG
                     VFVIKDSTAPSALVPGIEIDGIHIKVDNNMKTSIDGCFAAGDCVGKPYSYIKAAGQGQ
                     IAALNAVYYLDKLKRA"
     gene            21661..22029
                     /locus_tag="PC466_002403"
     CDS             21661..22029
                     /locus_tag="PC466_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HDF2769772.1"
                     /translation="MENLVKIFKALSDETRLNILILVSKRNICQKGISKYLGISDSAV
                     SQHIKILKDVGIITGYKEGYYVLYHINKESFNICVDFINSMLSNSSESFIDVFDVNTI
                     HLGCSKECKSIKKCCKRREK"
     gene            22032..22403
                     /locus_tag="PC466_002404"
     CDS             22032..22403
                     /locus_tag="PC466_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NifB/NifX family molybdenum-iron cluster-binding
                     protein"
                     /protein_id="HDF2769773.1"
                     /translation="MKVCIPVEENKGLDSKPYGHFGSAPIFVVCDLESGEVKSLDNGD
                     LDHEHGKCQPLKALSGTAVDAVVVGGIGQGAIIKLNGMGIKVYRAEGDTISANLDLLK
                     NGKLVEFPSDHTCSHDGCGHH"
     gene            complement(22547..23002)
                     /locus_tag="PC466_002405"
     CDS             complement(22547..23002)
                     /locus_tag="PC466_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769774.1"
                     /translation="MNINTVQGDSIEVLLRQLGATRISKVSSTLYFIKFDLGDGWEIS
                     YTYNINAKDQYFLQRIEPYPIGRGLFNDEYEIVSFISKDLKKFLNAKNSSNFKTFVEV
                     TRKVNSIIDNVEELFLNYNVDGDDLKTLNKELNDILNDIDYIEKHTKKI"
     gene            complement(23041..24306)
                     /locus_tag="PC466_002406"
     CDS             complement(23041..24306)
                     /locus_tag="PC466_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsB/NhaD family transporter"
                     /protein_id="HDF2769775.1"
                     /translation="MEFQQIIAICIFLIVMAAIITEKVNRSVAAVGGALLMIIFNILT
                     LDEGLSHIDFNTIGVLVGMMLFVAVVKNSGLFEYIAIWTAKKAKGDPWKIMICFAIIT
                     AILSAVLDNVTTVLLIGPMTIVITQILGLNPVPFLITQILASNIGGTATLIGDPPNIM
                     IGSAANLSFMDFVINLGPAVIVILAITIICFRFIYGKELVVNERAKNAILKLDEKKSV
                     KDKPLLIKSLILIAFILFGFMFHSTIHIDSSVVALTGASIMLLIGKQDVDEIMAGIEW
                     STILFFMGLFVVVGGLVEVGIINKLAQALIGLTEGHLVFTMLLILWLSAIVSSFLDNI
                     PFVATLIPLILTMQAEGIDVMPLWWATSLGACLGGNGTLIGASANVVLAGIGNKHGHP
                     ISFKEYFKIGFPLMIISIIISTVYLIIKF"
BASE COUNT         9492 a         2706 c         3800 g         8591 t
ORIGIN      
        1 ataaaaaatt tatataaata aaatgcttgt ttttcttgta ttatttatat aaatattgaa
       61 atttgtctag ttatacgttt ttattgacca gttatgcagt tgatattgaa tattctaaat
      121 attggtgtta ttttataggt ggtttaaaca tattaggggg attttatata tgatttgtat
      181 gatttataga gaatgtataa aatagtaaag gtttagagca tgtttagtgg attgcagaat
      241 atgcatatag aatgattctt gtaaattaag ttagacatag gaaatatata atttgtattg
      301 gatgattgat tttatggtgt atgcttttaa cttctataat gggaaagtaa agatgtactc
      361 ccaatacatc tttactttag cagaagttat agttacttat aaagtacaaa aaattatata
      421 tttattagag tagataaatc taaaaaggtt tttctagaaa aatttaattt taattgtatc
      481 tacttactaa taataagact tgatgtaagc aggtttcaac taccgtttct ccatattctg
      541 atataaaatc atctaactgt gtatctaaaa aattacaata atcatatgaa ctactgatgt
      601 aagcagttag tatatgtgta catttgtcta tttctccaat aaacatatta tccatccccc
      661 taaaaaattt agtaaaaata aaaagtcgca ttctattagt caattaacat aatttataaa
      721 attttttagt actagtttct ataacttaac tccttaaggt taaatattcc cagttttacc
      781 aatttagttt tattctacaa gtatataata ctagaagatg cttcattatt caacatgctt
      841 gtttgagaat agaaaatatt ctaaaattat aattgttttt aaaaataaga ttcaagataa
      901 ataaagttat atgcaactat ttaataatct ttccataata aggacagtag gttctattct
      961 taaaaaactc catctttaaa tttaaagaat aactacaatt tgaacaacaa taaaatttcc
     1021 aatcaataaa aatatcaaaa ataataaaaa taattgaaaa tgtataattt cccagaaaaa
     1081 taataaatgt aactccaata ataaacacac ctataaatta taaaataatt taagctttat
     1141 ttaaggttag tattatattt atataagatt taagttttaa tatatatgtg taattaaaat
     1201 gatttaggag gagaaatata ttggtaaatt gggaaataaa aaaattggct aaatctaaga
     1261 gtatgtttat atctctaggg atattagtgt taatactaat gattagtatc tttattacgc
     1321 ctgttttaga aacagaacgt tattatatag ataaagaaaa aggatgtata gaagatacga
     1381 gaagtggtat cgacataggt aatgagaaat ttcaaaataa gattaatgtt ttaaagcagt
     1441 tttcaaatca aacagataca ggtgaatttt ctaaaaaaat tgaattaatg tcaaagaaaa
     1501 aacttgataa tctaagtgtg aatgaatata aggatattag tttttggaaa gtatttaact
     1561 atagagttac aaattcactt ataaatgtag gaatgttaat cattatatct ataattatat
     1621 ccaatattta cgtagatgaa gtcgttactt cggtaaaaga tatcatacta tcatcaaaag
     1681 agaagaaaaa agcattaaag tctaaaatat ttgttgcttt attagttcca ttagtaattt
     1741 attctgttta tttaatggga atatttatta taacttgtat gcaacaagga gtacctgtta
     1801 atggagactt agaatctttt agaatagtag acaatgtagt tgcattgaaa actaatttaa
     1861 gtataacaaa gtatgtaata ttaaatatag gcatagagct tttgatgttt gaaggatggg
     1921 ccatgatagc catatttggg tcttttataa gtaaatcttc aatatcttca ataagttttt
     1981 ttatatttat tatatctata actaagataa tgtcggtaat ccatatatta cctaaaaaat
     2041 tactttcagt tgtatcaaat gtaaattatt atgatttgat atttggtttt aataaaataa
     2101 taggaaatta tctaggtgat attatgatat ttaaagtgaa tatagacatt gtcaatatag
     2161 caataggact tttgatggca atattgatag gtgctatgtc attatgtttt ttagtaataa
     2221 aatcagatta tataagtaga taaaagggga gttaagatga ataaattaga aatagaaaat
     2281 ctttcaaaga tatatggtaa aaaagtagca aacgacaaga ttacagtaac tctggaaaat
     2341 ggagtttatg gtcttctagg accaaatgga gcaggaaaat ctacattaat gaaacaaata
     2401 acaacgttga taaaacctga tgaaggtcag atactttata atggtgagga tatatttaaa
     2461 atggatgcta attatagaaa tattttagga tatttgccac aagaatttgg agtttataaa
     2521 aattttacag caaaagaatt tttacagtat attggagctt taaaaggttt aaggggaaaa
     2581 tatttaaata gtaagatagg agaattatta gatttagtag gtctttacga tgtgagaaat
     2641 aagtctatag gaaaattttc aggaggtatg aagaggagag ttgggatagc acaagtttta
     2701 ctaaacgacc ctaagataat agtctttgat gaaccaacag caggtattga cccacaagaa
     2761 agagctagat ttaggaattt aatagcaaaa atgtctagag ataagataat aatactttct
     2821 actcatataa tttccgatat agaatcagtt gcaaaggaaa caataatgat taaagatggc
     2881 aaacttctaa tgaaaggaac acacaaagac atattaagtc acatggaaaa taaagtatat
     2941 aatgttcaag ttaaaaatga atgtgaagtt gatgatatac aatctaaata taaggttgta
     3001 agtattcaaa gtgatattga ttcagtagta cttagaattg tttcagagga tattccaagt
     3061 ggggataata tacaaccagt tcaagcaaaa ttcgaagatg tatacatgtt ttattttgat
     3121 ttggaagatg caagggaggt gtagtagaaa tgatgtattt agttaaagct gaaatgataa
     3181 aaatattaaa atcaaagagt gtttggataa tttggctgtt tttaatattt ttgggatttc
     3241 ttctgattag aaagtttgat gttttagata cttatgcaga tatattttac aagatagaag
     3301 gctcaatacc tctaataggt ttgataatgt ttataataac ttctggaaat tacattaaag
     3361 aatatgattc taatatgaca ggtttaataa atacaactaa aaagggaaaa aaatcagtag
     3421 tattatcaaa actagtagct aatggattaa ttttatctat tattaatatt tcttttatat
     3481 tgttagtagg aattagaggt tttagttttt ttgattttaa aaatttaaat gaaccgattc
     3541 ataacttatg gtactttgga aatagtaatt taaatcttac agtaatacaa atgtatataa
     3601 ttgttatatt gactactatt tttgcttctt ttatatttgc acaaataggc ttaacacttt
     3661 catctatatt taaatcggct gtaattccat ttatactagg tggattgata atggcaattc
     3721 catactttag tgtaggtttt ataccagata aagctataaa atttatgtca gtgactccaa
     3781 attggattat gatgagccaa caaatggtta ggtataatgt accaagtatt ttgatagttt
     3841 tttctatagt aatctcaatt atattaatga tagtgttaac taaaataaca tatgaaaatt
     3901 ttacatcaag caaaaggttt taactaaaaa taatagtaat tttatttata ttttagttta
     3961 attaaaaata agataaatga attttagata aaatatatgc taatatatat gtaaattatt
     4021 acaggaggtt gtttatggaa aatcgtgttt taataataga tgatgaagta gaaatattga
     4081 agcttttaga aactgtccta aaaaaagagg gccttaataa tatatatact gcaaaaacta
     4141 aaaaagaagg attagaatta tttaaaagta ttaatcctga tttgattgta ttggatatta
     4201 tgttaccaga tggcgaaggt tatgatattt gtaaagaaat aagaaaaacc tccaattctc
     4261 caataatatt tttatcagct aaaaccgaag aattagataa gttacttgga ctagcgattg
     4321 gaggagatga ttatgttaca aaacctttta gccctaagga agtggctttt agagttaaag
     4381 cgcatttgag aagattaagt tattttagtg atgttcaaaa cgaaagtaaa aatctaaata
     4441 agaatgaaga aaaaattata tcatttggcc catatatatt aaatgaaagt agggcagaac
     4501 ttataaaaga tggaaaatct ataggactgt ctgcaaagga actaaaaatc ctatctttat
     4561 ttgcacataa tcaaaatcaa attataagta aagaaaaact atgggataaa gtgtggggag
     4621 aagattatgt tggatttgac aatactataa tggttcatat aagaaaaatt agggaaaaat
     4681 tagaggataa tccttcaaag cctgaatata ttctgacaat aaaaggtctt ggatataaat
     4741 tagcagtaaa ggaagattag aatatgaagt ggaagattac tagaaatttt atatttacaa
     4801 ttgtgtttgt agctatatca gtagtaatta taaatattat atctatattg tatgtgattt
     4861 caactaatag cttttttaaa gttgtagatt ctggaaataa tcctgaagaa tttgcacgtt
     4921 cttttgaaaa agatttatat gaaaaagatg gagaatttaa actatctaag attggagctg
     4981 aaaaattaga aaaatcaaat tcctggatac aggttttaaa tgatttagga gaggaagttt
     5041 atggagtaaa tgtgccaaag gatactccaa aaaaatatac accctttcaa atggtgaata
     5101 attacaagta tatagaaaca aagtatgtta attttgtact agaaaaatat ttaaacaaaa
     5161 aacatctaaa cataatagta ggtataccta gtagagatat atcaagaata attttaacct
     5221 attctcaaaa taacattaaa aaaactttaa ataaagttat cattataaca ctagtaattg
     5281 atagcgtggt agctttaggt gtaggatatt tatttagtag aaaacttaca aaaccaattt
     5341 caagcgtact atggagtatt gagactatgg ctaatggaaa ttatagttta tatcttaagg
     5401 acagaggtat atatgaagaa gtttttaaaa atataaatat gttagctgat actttaagag
     5461 taaatgaagt tgagagaaaa gaaaatgaag agttgagaga ggaatggctg gcaaatataa
     5521 cacatgatat aaagacacct ctagcatcta tacaagggta tgcagagata attaatgaca
     5581 aagattatga gtttgaagaa gatgaaatac gagagtatac agaaattata tataataagt
     5641 ctaagtatat aaaagattta gttgatgatt taaatttatc tactcgatta aaaaataata
     5701 ctatagttct ggacaagaaa aaaataaatt tagtcagttt agtcagagat ataataattg
     5761 atattttaaa tgataataga tataaaaata ggaatattga atttgaaagt aatgaagatt
     5821 taattgaagt atatgtagat tcaatcttat tcagaagggc tataaccaat cttatattta
     5881 attcaatagt tcataatagc gaaggaactt tgataagtgt agaaattgta aaaaaagata
     5941 atatagaaat tataataaaa gataatggaa ttggaataag caaaagtgat ttgaaacata
     6001 tttttaaaaa atattataga ggtactaata caggtgagat gcataaaggt tcaggtcttg
     6061 gtatggctat ttctaaagaa ataatagaga ttcataaagg taaaatttat gtaagtagtg
     6121 aaattggaat aggaacaaaa attattatag agataaaaca aaattaggag atatgatatg
     6181 gattttttta aaaaaggtat aagtgggttt actattaaga ttttagcatt aatatttatg
     6241 acatttgacc atatagcagc atttatgcca caaacaatgc aaataccaat ttggtttcat
     6301 tgggtaggca gaatatcagc accactgttt atattcatgg ctgttgaagg attttatcac
     6361 actagtaaca gaaaaaaata tataagtaga ttgtatattt ggtctgttat tatggctata
     6421 ggaaatcaaa taattaataa tgtattttca catccagaag gagctataat tataaataac
     6481 attttttcaa cattattttt aatagcgatt tatttacaag caatagagtt cataaagaaa
     6541 tttagaaaag agaaagaaat taaatatttt attataggat tattgatgat aatcattcct
     6601 ataattttag gaatatttac agtagcttta ctttttaaag tcactaacag agttattact
     6661 ttatttatga ttttggtacc agtaccattt ttagtagaag gtggaccaat ttggattata
     6721 cttgggatta ttttttattt gtgtagaggt aaaaagttca gtttgagtat ttgttatgtt
     6781 ttgatgtgta tatttatatt tacaacaatg tcaaatggag attatagttt aaaaaattct
     6841 attttacaaa attaccaatg gatgatgatt gcttctctac ctttaatgtt actttacaat
     6901 ggagaaaaag ggaagagtat gaagtattta ttttatttat actatccaat ccatgtatat
     6961 atattgtata tcttaggaat atacttaata aatggttttt gattgtaagt gatattttta
     7021 atacaaaatg aacaatatga ggattgtttt aggtctatta aaattgttat ttagatgaga
     7081 tttgtagaat atttaaattt atgagcagaa attcagttat tgtaatttca ataacattag
     7141 aatataatat tataatttat ttagaaatat atgatgttat atatggtttg gttattaatg
     7201 taataataaa atagaggttt gatataaaat tcaatacctc tgttttagtg ttttttatcc
     7261 tatatttata cttattttat ttataaatta gtgttttgtt ttaattaata ttagtgcatt
     7321 ttttatttat tttataaaat tagtcataat tgtttcttca tattgtggtt ctttaattcc
     7381 agctttttta cctgctgata tacacttaag aagccatgcc atgttttctc ctagagttcg
     7441 catagtctgt aatccttctt catctttcat aacatcctct ggagtaaagc catgtacctg
     7501 attccaatac tgtgatgata caataggcat attgctgatt gaaaaatatt tatttagttg
     7561 gtcaaatgtt gcacttgcac caccacgtct acatgacaca actgaagcac ctaattttgt
     7621 agccatgcga cttccagcta tgaaaaatag acggtcaaga aaagaagtta attgaccagt
     7681 tgcactagaa aagtaaacag gagaaccaat aataatacca tcaatattat cgagatcttc
     7741 aatcaattca ttaactttat catttcgaat acattttcca gtttcaaaac aggatgcgca
     7801 actaatacat cctgggattg cttctttacc taaatacagt atttctgttt taatatcgtg
     7861 tttactcaat actttagtaa tctcatttag tgctgtataa gtacatccat attggtttgg
     7921 gctaccgttt atcaataaaa ctttcattat aaatttcctc caatgaattt tatttaatag
     7981 attttctaag agatattatt ttttataaaa taggattttc atgaatatta tcaatttata
     8041 tagaaatgtc taatcttaga atcctattta aaataactct ttttttagta aatacacctc
     8101 ctattataaa attgactttc aattattctt acactataat tttattataa attattctaa
     8161 aaacaagtac gcacattttt gttcaatact aaccaaaagg agagtgtaat atatgagtat
     8221 agactgtata tcaaatacag atttaagtga aacaggattt agttatacac tttcactgat
     8281 tagtggtaaa tataaaatga taattcttta ctgtcttgta gaatttgaag ttgtcagata
     8341 taatgcatta aaacgttata taaatactat ttcctataaa actttgagtt tatcattaaa
     8401 agaattagaa gcagataact tgattattcg tactgaatat cctcaaatac ctcctaaggt
     8461 agaatatagt ttatcagaaa ggggaaaatc tctgattcca attttagatg caatgtgtga
     8521 gtggggagag aggaatagac cttaattttg tatctgtaga tgccataaaa agactgtgag
     8581 taaaattgtt tgaataatct actcacagtc tatatttaaa ttaatagtta gtatttttaa
     8641 tttataaaat actaaaaaat ttattatgaa atttcaccac caatttcttt tacatcttct
     8701 ttgtatataa tacaagcttc tatagctaat tctaaacctt ttactatttc ttctaaagac
     8761 atgaatggtg tatttttttt atttattacc tgtgaagttg tatatgggat gtgtataaat
     8821 ccacccttta tattaggata tttcttgtct atcatataaa ggattccata catcacatga
     8881 ttacaaacga atgttcctgc agtgtttgaa acactagctg gaattttatt ttcattcata
     8941 tgttttacca tggcttttac aggtaatttt gaaaaatatg caggttcacc atcttctttt
     9001 ataatagtat ctataacctg gttaccttca ttatctttta ttctaaaatc atctatattt
     9061 atagcaactc tctcaggtgt aatgtcaaat ctacctccag cttgtccaac tgatattact
     9121 atatctggat tgtgctcttg aatagcttta tctatagctt caacagattt tgtcataact
     9181 gttggtatag ttatctttat gatttctgca ccgtttatat tattattgac cctttcaact
     9241 gcttcttgag ctgggtttat tagttctccc ccaaatgggt caaatcctgt taacaaaatt
     9301 ttcattattt tacctcctaa ttatattaaa atcctaaaaa gtacattact aatatgtggg
     9361 ctataattaa taccaaagca actggagctt gatattttat aacaatataa tcatttttac
     9421 attctagcaa ggctgctgga actatattaa aattagcagc cattggagta agtagagttc
     9481 cacaatatcc tgctgttaat gctaatgctc caattatagc aggatttcca ccttgagaca
     9541 atacaaaagg aataccaatt cctgccgtta tgactgaaaa tgcggcaaat gcatttccca
     9601 ttatcatggt aaatataacc atacctaata cataagctat aacaccaaat aatctgctat
     9661 cagcagggac tacaccagat atcatggttg aaataacttc gccgactcca gcctgagtaa
     9721 ataaagctcc taatgcaact aaaagttgtg gtaacatact agcaggtccc atttgttgaa
     9781 gtaatcttga gccatcttga actgatgtag caggttttgc tttagttatt ataagggctg
     9841 atattaatgc aattattgaa cccacaccta ttgcaaattg agaagaatta tcaaaattag
     9901 aaaggctcat agctactact actgcagcaa atgctaatat taatgatggt ataaatattt
     9961 tatttttaag tttgtctgct tgttcttttc caaaattttc atctggttct tcatactttg
    10021 caaatacaac ttgtttagaa agtgttaata aactagataa tattaatatt attcctatta
    10081 tattggctgg aatcaatcta ccaaatatga atggcagtga tataagtatc caaaataatg
    10141 atgtaccata tttcttattg ttatttatgg tagtaaaaga cttatatgct ataacaatca
    10201 ttaaaaatcc cattagtgcg taaaagattt ccaatgatat gtttataaaa ttttgcattt
    10261 ttattcctcc taaataaaac tattttttat gacttttgtt taatttttta tcatataagg
    10321 taaactggat tgtagccact acaagtgcta ttactgccat aatagtacta gcctttacaa
    10381 tattaagtcc agttacattg tatccaaatt gagttagagt agatgctata agtaatactc
    10441 cactactacc tgcaaataag ttttgaccat aaaaatttcc atagttttct gatgcagcag
    10501 ataatgcctt tatggcttct tcatccgatt cttttagttc atcactatta cttaaaccag
    10561 cagcttgtgc cataggatta acaagtggtc ttacaaattg aggatgtcca ctcattctta
    10621 ttgatagagc accagctatt tgtctagcta tcatgtatat agtaagtact tttcctgttg
    10681 taagtctttt taatttttct attaaagaaa cagctctttg ttttaaacca tatctttcta
    10741 atacaccgat tactggcagt gttaatatga ataatgatac acctctgttt gagacaaaag
    10801 aatctcctaa aattgtaaaa atttgattaa aatctaatcc tgcaacaatt cctgttgcca
    10861 ctcctgctaa taatacagta aataatgtgt caattttaag tataaatcca attacaacta
    10921 tcaatatacc gattagtttt atcataaatt gttctccttc catttctata tgttttaatt
    10981 taaatttatt taatggataa agttaaactc tttttatagt atttgcgtta ataggactat
    11041 tattataaaa tttaataaaa aatagggaag atgttttaaa gtatcaaagt aaataatggt
    11101 tgtgtatagg aatttgagta acaaagatta tattttaagc taatatgaat tgattttgta
    11161 agtctatggt ttaagtatat gtcaatattt gaaataggtt ttaaattaga tattatatta
    11221 taaaaagaga atgtgtcaaa catagagaca agtgtatttt tctcttttga aatgataaaa
    11281 atatatttga tttcatacaa aaagagagtg tctaatgaac tttttagttc attagacact
    11341 ctctttttgt tatgattaat aaagcatata ttaagagcta gtttcattag atttcactaa
    11401 gaaaaataaa attttgataa agtttaaaga ctattttgag caatattact tataaataaa
    11461 agaatttatc atagaaataa ttagttttat tttagctatt aagatttatt aaaaaattat
    11521 ctatattatc ctgtgatatt ctaaaactgt cataattacc ttttgaaaca gccttcataa
    11581 taagtttatc taaaaatttc attttttcta atcgagcttc actaccaaaa attccaatag
    11641 catttgcact ttctaataag gatgatggaa aatttgattt taaatattta tctgcttgtt
    11701 cagaaaagcc acagcaaagg aaaatgccaa cttgtttttt gtttaataac tctacattat
    11761 cattacatag cacttgtatt ttttttgaaa ctgaaccaac atatatagaa cttccaataa
    11821 taattttatc aaattttgat aactcaattt tattattatt attaatatca acaatagtga
    11881 cattatctga tagtttattt tttagtatat ttgcacagtc ttttgtacaa ccatatttac
    11941 ttgaatatat aataatagta ttcataatta ttctcccttt cttaaagcat tttctacagc
    12001 ttttcgtata gtattactgc tataagttgc agaagttata gcatccacat ctaaagactg
    12061 ttgtttaata atacttgttg taattttttc agcaggttta cctaaaagat ggtcgtgttt
    12121 taagatatta atattttgga ttttaccatt attaacttca acagacacag tagcttttac
    12181 caagttatta tcagcacttc cagtataaat gccattttta acattattaa tatctatatc
    12241 ttttactacc aagttttctg gctttaagtt gcttacaatt acaataataa tgcatataaa
    12301 tacaaagaat agagcaatag atatttttac atattttttc tttttattag tagctttgtt
    12361 gcgaattttc attgtaaagt cctcccacta aaatatctaa gaaattttct ataagttgag
    12421 aaaaattatg taaagaatat agtttatttt caacaacaca taaaacgaat cctaacaatg
    12481 cacttataag catccatgag cttttatcta tatttttttt gaatattcct tgttcaattc
    12541 caatggaaag gaatttatca agcattttta taccattatt gctaggagta ttgtttgtat
    12601 tttcagatgc aaatataata ttcattctac tatgcatgat agcttttgcc atctctggtt
    12661 cactagaaag agtttttata aagctagtca taatttctat gatttgttta tctattggta
    12721 gtgatgagca attattcata atgtcaatag cattactttc tactgtgtta taaagtttat
    12781 tggtcatatc gctgataatc tctgctttgt ccttgtagta aagataaatt gtagttggag
    12841 aatattctat ttttgtagca atttttctta ttgataaatt ttcatatcca tgttggttta
    12901 taatttcgat gctagcatcc ataatctttt tcttcatttc ttctttttca tttttacgtc
    12961 tttctttgat actcatataa tcacctcttt gcttaacggt gttaagttaa tttacactgt
    13021 tattgtataa tttaatttta atactgtcaa taaattatta aataatataa gttaatatat
    13081 ttttatggat aataaattaa tgttattaat tgtaatattt aagatattat tgtataataa
    13141 taatcggttt aaatgcgcca catcttatta aagttggttc ataattctaa ataaacttta
    13201 ataagataca ttaaaatata ataaattctt ttatgctata aaatttattt tatagctatt
    13261 aaatcagatg tttaaaaatt ttttaacagt ctatagtttt taagagtcta tagtaagtag
    13321 cctaaaaata tgattttaca tctgtacttg ttcgagaact ccaagtataa aaaactaagg
    13381 aattatatag tggcagtata taattaatac ccttagacac acctttttga aagtggaaaa
    13441 aagatgtgta gttctcctcg accacaaatc aaggaggata aaaaatggaa aagagaaaag
    13501 taataattga ttgtgaccca ggaattgatg attctttggc aattcttctg gctttaaact
    13561 caccagagct agaagtaatt ggaattacca catgttgtgg aaatgttcca gcaaatatag
    13621 gtgcagaaaa tgcactaaaa acacttcaaa tgtgttcttc actaaatatt ccagtatata
    13681 taggagaaga agcaccacta aaaagaaaac ttgtaacagc tcaagataca catggagaag
    13741 atggtattgg agaaaacttt tatcaaaagg ttgtaggagc taaagcaaaa aatggagcag
    13801 tggattttat aataaatact ttacataatc atgaaaaagt atcaataata gcacttgcac
    13861 cacttacaaa tatagctaaa gcacttatta aagataagaa agcatttgaa aatctcgatg
    13921 agtttgtatc tatgggagga gcatttagga ttcatggaaa ttgctctcca gtagcagagt
    13981 ttaattattg ggtagaccca catggagcag attatgttta caagaattta tctaaaaaaa
    14041 tccacatggt aggtttagat gtaactagaa aaattgtact tactcctaat attattgagt
    14101 ttataaatag acttgataag aagatggcaa agtatataac tgaaataact agattttata
    14161 ttgatttcca ttgggaacag gaaggaataa ttggctgtgt gataaatgac cctctagcag
    14221 tagcgtactt tatagacaga agtatatgta aaggatttga atcatatgta gaagttgtag
    14281 aagatggaat agctatgggt cagtctatag tggattcttt caatttctat aaaaaaaatc
    14341 ctaatgcaat tgttctaaat gaagttgatg agaagaaatt tatgtacatg tttttaaaga
    14401 ggctttttaa aggttatgaa gacattatag actctgtgga aggagtgata tagtgtgaaa
    14461 agaaaaatat gtgtaaaaac tattacactt atagcttttg gtatttctat aaatataata
    14521 ggcgctttta tagctatggg attaagatta cctgtatact tagattcaat aggaactata
    14581 atgatagctt cacttttagg acctaaatac gctgttgtta caggtgtgtt tggaagttta
    14641 ataagtggaa ttacgtttga tgtgtattct ctctattttg caccagttca aatatcaacc
    14701 ggattacttg ctggaatagc atttaaaaag aattttttaa ggggtttaaa aactccacta
    14761 ggagtacttt tatttgctat tccaacatct ataataagtt caataatttc agcattttta
    14821 tttggaggta tgacctcttc aggttcatcc tatatagtgc aaatcttgaa agtgttagga
    14881 ctgggagatg tttttagtgt gtttgtaacc caagtattta ctgattatgg agataagctg
    14941 ttagcagttg ttttagtgaa tttaggatta aatgcagttc caaaaacttt aaaggtatca
    15001 ttgactggag gaaaatagat agaaaatgga tagatatagt gagataacaa ataaaaatca
    15061 aagagaaatt gttctgctta aaggatttcc ttgtatatgg ggaaagtgtt ctttttgtga
    15121 ttatatagat gataattcta atttagaaga agagatgaat aaattaaatc taagggtttt
    15181 aaaaaatgta actgggaaat atggagttct tgaagtcata aattctggaa gctgttttga
    15241 attacctaag gatactttag aaaaaataaa gtgtattata aaagagaaga atataaaaaa
    15301 attattttta gaaagtcatt ggtcttacaa aaataggctt aaggaaatga gagagtattt
    15361 tgaaattcct gtggtattta aaattggagt tgaaaccttt gacaatgatt ttagaaataa
    15421 tattttaaat aaaaatgcaa attttaagac tccacaagat gtaaaagaat attttgattc
    15481 accttgtatt atgattggaa taaaaggaca aacaaaagag atgatagata aagatataga
    15541 gattatccta aatacttttg aaaaagcgac agtgaatgtt tttataaata attcttctag
    15601 tataaaaaga gatgaagagt tagtgaaatg gtttgttagt aagtataaat tcttggatga
    15661 aaatccaaat atagaagttt tatacaataa tacagacttt ggtgtaggag attagcatta
    15721 atttagttta aatttaaaat tgaaaagttt cttatgtttt tgaaaaagct tctaatagtt
    15781 agaagctttt tttgtagagt tttatgttac aataagaaaa aaggaattaa ggagcaatta
    15841 aatgatgttt gataggggaa aatggaataa attggattat aatgaacttt tagaatatat
    15901 gatgtctata aaagatataa aatatagaga ttttaataaa aagcttatac ctggaacaga
    15961 aaatataata ggtattagag ttcctaattt aagaaagtta tcaaaagaaa taagccaagg
    16021 gaattggaag gaatttttag aagtagcaga ggatacatac tatgaagaag ttaggctaca
    16081 aggtatggta attggcaata taaatagtaa ttttgaagaa actttatact atgtaaaaag
    16141 atttatacct aaaatcgata attggtcagt ttgcgatggg ttttgttctg gtttaaagtc
    16201 tatgaaaaaa tataaagaaa atatgtatga tatacttaaa aaatatgttt attcaaagaa
    16261 tccatgggaa attagatttg cattagttat gtttttaata tattatgttg atgataaaca
    16321 tattaaagaa atatttgaat actgtaataa tatacaaagt gaagaatatt atgttaaaat
    16381 gggtatggca tggttgctat caatttgttt tattaaatgt gaagaggaaa cttttctcta
    16441 tataaaaaat aataatttag atgatttcac ttataataaa atgctacaaa aaataattga
    16501 atcaaataga gtagatttag aaaagaagaa tataataaga agtatgaaaa gaaagacaag
    16561 aagatgttga cggaggaata ttaatgaata acaatgaaga cagaattgac aaatttttag
    16621 aacttcaaag caaaggattt aaatttgcag agatagctca aaatctaaag attagtcaaa
    16681 gtactttaag aactttttta aataaaaaag gatataagtc agaaaaaggt aaatacatat
    16741 taaaagacga attaaattat aataaaagtt tggataatag aaacttggaa gaagagaaag
    16801 ctaaggagta tgaaaaaagt aaaaagaata ctataagtaa tagaaaaaaa gtaagcacca
    16861 aaaaaaagat ttctaatgaa aaggctttaa gtaaaagtgt tgaacaaatt gagtttaatg
    16921 atacaggttt aaaaaatgca aagcgaaaac aaaatgttaa gcctaagaaa gatagaaaaa
    16981 taaatataac tcaagaagat ttagataagc tttgtgaagt atatgattgg tatttagaag
    17041 taaaagatta caatataaag cctaaaaaag tatctaataa aaaagatgta catatagatg
    17101 atgaacacat agatgaatta aaaacaacaa gaatacgtat agataaagaa atatggaatg
    17161 attttgaaag attatgtagt aattcgaatt ttgaaaaaca tcaaatactt acacaggcat
    17221 tgaaagaatt tatgaaaaag tataaaaatc tactataaaa tactactata tgaggtgctt
    17281 aatatgaata aaatagtaaa aaaatcaatt tctctaatga ttatattaac aatatttatt
    17341 tttatgttga cagcatgtga aaaagatgaa cagcctgatt cagttgatat tcaaacagaa
    17401 gataaaaatg agataaaaat agatgaggga aatgcaaaag tattgaatat aggaaaatca
    17461 gaaattataa atatagatga aggtgataaa gtagatacat caacaaaggt agaaaataat
    17521 tcaacattta atatatccaa tgttgaattg atatataatg aatatgatga gaataaaaaa
    17581 attatatctt cggatagtaa ggctttgttg gatatgactt taatgcctgg gaaagttgct
    17641 tacatagaat gtgggcataa aacttttgta aagggtgtag aagtttatgc atatgaatat
    17701 gaggcagagg gtaagattgt gtatgttaat ttaaaagaaa atactattaa tataagaaat
    17761 aataatatta agctagaaaa tagtagtcag tatgaggtgc tatctacatc agaacttaaa
    17821 aaagtaaatg aatcaaatga gggaattacg tatcaagtaa aagtaaaaaa ttcatcatca
    17881 aaagatttag gaaatattat tcttaagaca gcagaagtta atgaaaatgg agaatattta
    17941 acagtaaatc gtgtaccatc atataagatt ttaaagcctt cagaagagac agatatagat
    18001 atattgtgtt caacaaaggc aaaaagtgtt gaaatagtgg gatatacgta tgatgatata
    18061 aaagaaaaag ccaatgtgga tattgactta aaatctcata aagttaagat agacaaataa
    18121 aggtagggga tacttatgaa ggttttaata gttgaagata ataagatact tttagaaagt
    18181 gtagtagaag aacttagcaa gcattttgaa actgaaaagt gtgaagatgg agaagaagct
    18241 ttatacttag taaatcaaaa tatatatgat ttagttattt tagacttaat gcttcctaat
    18301 ataaatggat ttgatatcct aaagaaaatg agagttaata atatagatac acctgtactt
    18361 atattgacag caaaagaaac attagatgac aaagtagaag catttactat aggagctaat
    18421 gattatttga caaaaccttt ttatatggaa gagttagtag ctagggtata cgctatatta
    18481 aggactaatg gaaagataaa agaaagaaac ggattagaat ttaaatcttt atatttagat
    18541 acactagaaa aaagagtgta tattgaaaaa gaagaaataa aacttcaaaa caaacagttt
    18601 aacttgcttg agtattttgt attaaataaa ggttcaattt tattaaaaga gcagatttat
    18661 gatagaatat ggggaattga ttcagatgca actattgaaa tagtggaagt atatgtaagt
    18721 aatctaagaa aaaagctaag taaatatgga tatgataaat atattaaaac taaacgtaag
    18781 gtaggatata tattcgatga taaataagaa tgtatttacc agtactaaaa atcatttaat
    18841 aaaaatgtat attattgtag taggtagttt tttaataatc ttttctatat ttatatactc
    18901 atattttagg ggacttacat atagtggaat tgatagtgag ataaatgatg aacttgaata
    18961 tatagtctct caatttaaaa gaacttcatt tttgaaccca ataagactga aagatcctaa
    19021 agatatggtg tatgtatatg aagatggaag gataagttac tatactcaaa atgaatattt
    19081 tgatgagtta cttccagata gaagactaga taaaaaaaat tcgtttttta aatacacaga
    19141 aaatggatat acttttagag aattaaatgt agatgtaggt agataccaaa tacagataat
    19201 tagaaatata gattctgaga tgaattcttt aagacagctt acatctgttc ttataattgg
    19261 aatattaatt tctgtaataa ttacttactt tgtggctgta tatctcacta gaaaagcttt
    19321 aattccaata gaaacagcat ggaaaaatca agctaagttt atacaagatg cttctcatga
    19381 attaagaaca ccaataacaa tagtttcatc aaaattagaa agtatgttaa aatccccaga
    19441 aagtacagta aatgatgaag ttgaaacaat agctactgca atgaaggaaa ctagaagact
    19501 taaaaaaatg ataactgatt tattgtctct tactaaagag gactctattg ttaaagttaa
    19561 tttagaagaa atagacttag aaaaattatt ggaagaaata tcagaagact atattgacat
    19621 tgctgagttt caggaaaaaa gattcgtgtt taattctaaa ctgaagaata aagttataat
    19681 aacagataaa aataaattaa gacagcttat attaattttc attgataatg cctttaaata
    19741 tacaaaattg ggtgatgaga tagcattaga attaaaagaa gatatagagg atgaggtaac
    19801 tttacttata agtgacactg gtataggcat aaaaaaagaa gagatacctc ttatatttga
    19861 tagatttttt agaagtgaaa atgtaagaaa taaagattta gaaggttctg gaataggact
    19921 ttcaatagct cgcatgatta gtttaaactt atctattgat ataaatgtaa cttctgatgt
    19981 agatattgga actacatttg aattgtcaat accaaaaaag ttaaaataat aaaaatataa
    20041 aaaattgttt ttagaaatga agaatgggta tactaattag tataaaatat aaaaagacct
    20101 tataaaagta aatttatatt tataaatttc atagtataat tatataggga taataaagtt
    20161 taataggagg atttaaaaat ggcaaaagtt ataaatacat ctgaatttag aagtagtgtt
    20221 gaaggtagta agggagtagt tgtagttgat ttctttgcaa cttggtgtgg accttgtaac
    20281 atgttgggac ctgtatttgc agaattaggt gaagagatga aggataaagc tagatttgta
    20341 aaagttgata tagatgagag cttagaaata gctcaacaat tcaatgtatc tacagtacca
    20401 actatgatta tatttaaaga tggaaaacca gtagaaactt taattggatt catgccaaag
    20461 aacaaaattg aaatgcaagt aaaatcatat ttataaaaaa tgggtgagta ttatgagata
    20521 tgatatagct ataatcggca gtggtccagc tggattgtct gctgctataa atgcaaaaat
    20581 aagaaataaa acaattatca tgtttggtaa tgataattta agtaataagc ttgttaaagc
    20641 tccttcaata gataattatt taggttttta tgatataagt ggtgatgaat taaaagacaa
    20701 gtttaaatca catatagata gtatggatat ttcaattgaa aataaaagaa taaataatat
    20761 ttatgctatg ggagaatact ttacaataat gtctggaaat gatatgtatg aagctactac
    20821 tgtaatcctt gcaactgggg tagagtatac tagaccaatc aagggtgaag aagaatttct
    20881 aggaagaggt gtaggctact gtgctacatg tgatgcacca ctttatagaa ataaaaaggt
    20941 agcagttata ggatataatg aagaatctaa agaagaagca aattttttaa gtgaactcac
    21001 ttcaaagact tattttatac ctatgtacaa aaaagataat cttatgagaa gttcagataa
    21061 cctagatgat tctattgaag ttatacatga cagaccagta cagatagatg gagataaact
    21121 tgtaaacaaa gtatctttta aagaaaacca cattgaagtt gatggagtat tcgttataaa
    21181 agatagtacg gctccaagtg cattggttcc tggaatagag attgatggca ttcatattaa
    21241 agttgacaat aatatgaaga ctagtataga tggatgcttt gctgctggag attgtgttgg
    21301 aaaaccctat tcttatataa aagcagctgg tcaagggcaa atagcagctt taaatgctgt
    21361 ttactattta gataaattaa agagggctta atatttatat tgattaactt tttaaagata
    21421 tttataaaaa actgtcttga aataatttta ttatttcaag acagtttttt atttttaagt
    21481 tattaataaa agtattttaa aatctatatg taattacttt tattaataaa attcaaagtt
    21541 atattagtag aaattggaat tatttataat atactccaaa atttaaaaat aatggttgaa
    21601 aaatctaatt aagagtacta taatttaatt aagtaattac ttaatcaaaa cgaggtactt
    21661 atggaaaact tggttaaaat atttaaagca ttgagtgatg aaactagact taacatactt
    21721 atattagtat ccaagagaaa tatatgtcaa aaggggattt ctaaatatct agggatttca
    21781 gattctgctg tttcacaaca tataaaaata ttaaaagatg ttgggataat aacaggatat
    21841 aaagaaggat actatgtttt atatcatatt aataaagaat catttaatat atgtgtagat
    21901 tttataaatt ctatgttaag taattctagt gaaagcttta tagatgtatt tgatgtaaat
    21961 acaatacatc taggatgcag taaagaatgt aaatctataa aaaaatgttg taagagaagg
    22021 gagaaataat aatgaaagta tgtataccag tagaggagaa taaaggattg gatagtaaac
    22081 catatggaca ttttggttct gctccaattt ttgttgtgtg tgatttagaa agtggagaag
    22141 ttaaatcttt agataatgga gatttagatc atgaacatgg aaaatgtcaa ccattaaaag
    22201 cattgtcagg gacagctgta gatgcagtag ttgttggagg aataggacaa ggagctataa
    22261 ttaaattaaa tggaatggga ataaaagttt acagagcaga aggtgatact ataagtgcta
    22321 atttagactt acttaaaaat ggaaaattag tagagtttcc atcagaccat acttgctcac
    22381 atgacggatg tggacatcat taaaaaaaac agctgatgaa atatatactt catcagctat
    22441 tttttctttt aataaatacg attttattct tttaaaacca aaatttagat ttttatgttt
    22501 tttgtagtat ccttaataat atttcaagtt tacaagttta ctacttttag attttttttg
    22561 tatgtttttc tatatagtca atatcattta atatgtcatt gagttcttta ttaagtgttt
    22621 ttaaatcatc accatctaca ttgtagttta aaaatagttc ctctacatta tcaatgatag
    22681 aattgacttt tctagtaact tcaacaaatg tcttaaagtt actactattt ttagcattta
    22741 gaaatttttt taaatccttt gatataaatg atactatttc atattcatca ttaaatagac
    22801 ctctaccaat aggatatggt tcaattctct gtaaaaaata ttggtcttta gcattaatat
    22861 tataagtata agatatttcc caaccgtctc ctaaatcaaa cttgataaaa tataatgtac
    22921 tacttacttt tgatattctt gtggcaccaa gctgtcttaa aagaacttca atcgaatcac
    22981 cttgaacagt attaatattc atatatacac atccccttta gtattattat actatatttt
    23041 ttaaaatttt ataattaaat aaacagtaga tataataata gatataatca taagtggaaa
    23101 acctattttg aaatactcct taaaagagat aggatgaccg tgtttattac ctatacctgc
    23161 tagtacaaca ttagcagatg ctcctattag tgttccattt cctccaagac aagctccaag
    23221 agatgttgcc caccatagtg gcattacatc aataccttca gcttgcatag tcaaaataag
    23281 aggaattagt gttgcaacaa atggaatatt atctaagaaa gaagagacta tagctgataa
    23341 ccataatatc aacaacattg taaatacaag atgtccttct gtaagtccaa tcaatgcttg
    23401 agccaatttg tttattatcc caacttctac tagtccacca actactacaa ataatcccat
    23461 aaagaataaa attgtggacc attcaatacc tgccataatt tcatctacat cttgttttcc
    23521 tattaaaagc attatagatg ctcctgtcag tgctacaaca gaagaatcta tgtggattgt
    23581 actgtgaaac ataaaaccaa aaagtatgaa tgctattaat ataaggcttt ttataagtag
    23641 aggtttatct ttaacagatt ttttttcatc tagttttaat attgcatttt tagctctttc
    23701 attcacaaca agttcttttc cataaataaa tctaaagcat attatagtta tagcaagtat
    23761 tactataaca gcaggaccta aatttattac aaaatccata aaactaagat tggcagcact
    23821 accaatcata atatttggag ggtctcctat aagagtagct gttcctccta tatttgaagc
    23881 taaaatctgt gttattaaaa atggaactgg attaagtcct aatatttgtg taataactat
    23941 agtcattggt ccaataagta agacggttgt aacattatct aatacagctg ataaaatagc
    24001 tgttataata gcaaaacaaa tcattatctt ccatgggtca cctttagctt tctttgcagt
    24061 ccagatagct atatattcaa ataaccctga gtttttgaca acagctacaa atagcatcat
    24121 accaactaat acaccaatag tattgaaatc tatatggctt aatccttcat caagtgtaag
    24181 tatattgaat attatcatta atagtgcacc accaacagct gctacggatc tgtttacctt
    24241 ttctgtaata atagctgcca taactattaa aaatatacat atagctatta tttgttgaaa
    24301 ttccataata taagtacctc catttgtatt attttgtgcc taatgctagt actatatata
    24361 gtattacttt tttattgttt tttcaatgga tgtatgaaag tatattattt aacaaagttt
    24421 ttgagaaatt gacagaattt aaagaaaatt tttgttattt aaataaattt taaaattatt
    24481 ccattgataa taatattaaa cgacaaacga aaaaatatac cctttaaact agaatttatt
    24541 gtatccaata acaattataa aatattaaat atatctatat tataaaaat
//
LOCUS       DAMJYN010000054        23892 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.055, whole genome shotgun sequence.
ACCESSION   DAMJYN010000054 DAMJYN010000000
VERSION     DAMJYN010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 23892)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23892)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23892
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.055"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            <1..597
                     /locus_tag="PC466_002407"
     CDS             <1..597
                     /locus_tag="PC466_002407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF2769776.1"
                     /translation="GLIKESSGQVLLNKHNLSNLAEHRRTQIVSRVFQDPSLGTCPSM
                     TVRENLSLALNKGKLLNLRKCLRYKRDFLENLLEGVSLDLKKYLDVQVKFLSGGQRQS
                     LSLIMSCLTSPSVLLLDEHTAALDPKTSNEVIELTNKIVREKNITTLMVTHNLKHALH
                     YGDRLIMLHKGEVVLDVKGKEKEQLTVEEILEKFEYAV"
     gene            728..1750
                     /locus_tag="PC466_002408"
     CDS             728..1750
                     /locus_tag="PC466_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF2769777.1"
                     /translation="MINKKRLASLILAGALSISMLTGCSQGGDSGNSKQESNSKGKEV
                     KKIGITQLVEHPALDATRIGFVKALEKNGFKDGENIDIDFQNAQNDMPTTQSIASKFA
                     SDKKDLIFAISTPSAQAAFNATKDIPILITAVSDPVAAGLVKTLEKPGTNVSGTSDFV
                     SVDKGLELLKIFAPKAKTIGVMYNTSEVNSKVQVDALKEYASKNGFKVVEKGITTSNE
                     VNQGISSLVGKIDVLYVPTDNLVASSMPIVSKIATENKIPVIAAESGPVEKGALACQG
                     INYEKLGYKTGEMAVKILNGESVSDMPVATSDDTDIIVNEDILKALGMEKPSNENISY
                     VKTKQE"
     gene            complement(1914..2471)
                     /locus_tag="PC466_002409"
     CDS             complement(1914..2471)
                     /locus_tag="PC466_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HDF2769778.1"
                     /translation="MTEKEKMLSGKGYYANDELLVKEREYCKKLTRLFNNTLEDEYEK
                     REDILRQLFGSVGKQINVEQNIRCDYGYNIHVGENFFANYDCIFLDVCKIEIGDNVML
                     APNVQIYTAYHPIDAQLRNSGIEYGSPVKIGDNVWIGGGVIITPGITIGDNVVIGAGS
                     VVTKDIPPNTVAVGNPCRVIKKIEE"
     gene            complement(2477..3553)
                     /locus_tag="PC466_002410"
     CDS             complement(2477..3553)
                     /locus_tag="PC466_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate/molybdate ABC transporter ATP-binding
                     protein"
                     /protein_id="HDF2769779.1"
                     /translation="MSLYVDIEKDLSSFKLKVEIKQEKGTLGFLGESGSGKSMTLKCI
                     AGLEKPTRGKIVLNDRVLFDSEKKINLSTQDRKVGFLFQNYALFPHMTVSQNIELGLL
                     KLSKSEKKEIVARYLDILKLNGFEGRYPWQLSGGQQQRVALARALATSPDILLLDEPF
                     SALDHHLRSNMEKELMNMLKDYKGDILFVTHDIEEAYRVCDDIIVYNKGEGLPKRPKK
                     ELFESPKYLIEAKITGCKNISKLNRLDKNTIYATDWGCELTLNREIGDNIEYVGIREH
                     HIKVLDSNEDLNEKLCFELINIVENPFTYTIYVRKTDLSNECVPIQIELEKSKMRFKK
                     GDRIYLDFPQEYLFCFRYNYNKKE"
     gene            complement(3554..4237)
                     /gene="modB"
                     /locus_tag="PC466_002411"
     CDS             complement(3554..4237)
                     /gene="modB"
                     /locus_tag="PC466_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter permease subunit"
                     /protein_id="HDF2769780.1"
                     /translation="MGTDWSPLWISLKTSILSTIITFVIGIFVSYIMANYRGKWKGLI
                     DGLFTLPLILPPTVVGFFLLLLCGKNGFIGKFLLNFDRTLIFSWTATVISAVVVSFPM
                     MYRTSRSAFEQIDNNMLSAARTLGLNEWKVFFKIAVPLAWPGIIGGLVLSFARALGEF
                     GATLMIAGNIPGKTQTMPIAIFFAVEGGDMNKAMMWVMIIVAISIAMILLLNYWSEFQ
                     QKIIGKRCG"
     gene            complement(4386..5198)
                     /gene="modA"
                     /locus_tag="PC466_002412"
     CDS             complement(4386..5198)
                     /gene="modA"
                     /locus_tag="PC466_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter substrate-binding
                     protein"
                     /protein_id="HDF2769781.1"
                     /translation="MKKILGILGLVACLTLGTVGCNSNEDKTDDGKQEKTTKSSDSVE
                     LNISAAASLKEAMAKIEEEYKKVDSNVKLTVNYGASGSLQQQIEQGAPCDLFISAGQK
                     QMKALDEEKLLVSDTMKDLVKNDLVLISSADSSVSGMKDLTTDKVKKIAVGEVESVPA
                     GKYADEVLTNLNLKDKLKDKLVFAKDVKEVLAWVQSGNADVGFVYFSDTVNNDKIKVV
                     EKTDEKTHSPITYPVSVIKASKNVDAAKKFEEFLLSESGQKIFEEFGYKKVE"
     gene            5391..6320
                     /locus_tag="PC466_002413"
     CDS             5391..6320
                     /locus_tag="PC466_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2769782.1"
                     /translation="MDSLSSLTPVEVAELLKITKNTVYELIKRGELPSYKVGKKIRVD
                     TKDVEEYINSQKTGKVKDTHFNNKNIDINNNFKIIISGQDVILDILARSVEKKLDGIS
                     TFRSYIGSYNALYELYNGRVSIASSHLWDFETDEYNSTFVKKLLPGIPCVLINLAYRM
                     QGFYVAKGNPKEITTWEDLTKPSITIVNREKGSGTRVLLDGKLRLLNFNGKHIKGYDN
                     EELSHLGVASTVSRGIADVGLGNEKAALQVNNIDFIPLHKERYDLVIKKEDLQNPVYQ
                     TIINIINSPEFKAELQGLGGYDLTDTGKTIAKV"
     gene            complement(6481..6930)
                     /locus_tag="PC466_002414"
     CDS             complement(6481..6930)
                     /locus_tag="PC466_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769783.1"
                     /translation="MKNKNNKDKNMLNIKVLRVLGVLLILFDYTGDTLNFYNFFAKPL
                     VSGNLYKTTGTDCIVFLLFIVECVYLVGRYILKVKINWSEIIENEKGNFINNLLVEKI
                     QEESNIVYNLLNSYVLPHIYKKARVLMFKTYHMLIYIKEKYYYVNIY"
     gene            complement(7133..8113)
                     /locus_tag="PC466_002415"
     CDS             complement(7133..8113)
                     /locus_tag="PC466_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF2769784.1"
                     /translation="MKNSFKNCISLRNKFIIISIVFLLILLIVSYIFGKLVYNSSVGL
                     EQLIKNEDIVKIFSERKDKPLEKLKNYKTSELMIQSSNNYKLESLFITSNIKTRDTMI
                     LVHGIGSSYYEMLKVAYRYLDKGYNVLVYNQRNTGNSGGDNYTFGLYERYDLDSLVKF
                     VKNKFPEGRLGVHGFSMGAGTAAMHSEINSKDDKVDFYILDSPYSEMKDAIRMGVLEK
                     RIPDILINYVVICGDLYNKFKSGFWYSDVKPYESVEKSNVPILFIHGTKDTVCNYQNS
                     KKMYDLVKHDKKDLWLIEGIGHVDGFEHDSTVYFNKIFKFIDSNVLSDKS"
     gene            complement(8318..9178)
                     /locus_tag="PC466_002416"
     CDS             complement(8318..9178)
                     /locus_tag="PC466_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-ADP-ribose hydrolase"
                     /protein_id="HDF2769785.1"
                     /translation="MAMKWRDYADDVNLFEDFDKTIKPLTDEQRRKNINTLIAYFSKE
                     VPSKIYNLSNDEIKPRDILRGLLNVYPPKEIAPEILNMLHNLLLIECEERELVDVNDI
                     EEVEEGIAIWRGNITNLRADAIVNAANNKLLGCLQPLHLCVDNEIHSCAGPRLREDCD
                     KIIKKQGHLEYTGDAKITRGYCLPAKFVVHTVGPIVSGGQPSKEQEKQLLHCYKSCLN
                     TIKEIDEIKNIVFCGISTGVFGYPKKEAANLAVSRVRLWLKENPEKNLKVVFNVFTEE
                     EEEKYRRIFK"
     gene            complement(9495..10823)
                     /locus_tag="PC466_002417"
     CDS             complement(9495..10823)
                     /locus_tag="PC466_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010963854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HDF2769786.1"
                     /translation="MEKFSVVIAGGGSTYTPEIILMLLDNLDRLPLRAIKLYDNDEER
                     QNKVAKACEILIKEKDPNIEYLATTCPKEAYTDVDFCLAHIRVGKLEMRELDEKIPLK
                     HGVVGQETCGPGGIAYGMRSIEGVLENIDYMEKYSPNCWMLNYSNPASIIAEAVRRLR
                     PNSRVINICDMPIGMEHNIARIAGLKSRKHMDIRYFGLNHFGWYTSIKDKKGNELLPK
                     LVEHIKEYGFINGEEGMKNDKKDSWFETNLFTKEIVKTDLTTIPSSYLKYYLFPDYVV
                     NHSDVNYTRANEVIDGREKEVFGSCALIEKQGHSKGSGLKIGIHAEFIVDLATALAFN
                     TQERMLLIVQNNGAIENIQDDAMVEIPCIVGKDGYEPLSIGKIPTFQKGLIEQQLAVE
                     KLVVDAWIEKSYNKLWQALMLSKTVPSATVAKELLDDLIEANKNYWPKLN"
     gene            complement(10971..11300)
                     /locus_tag="PC466_002418"
     CDS             complement(10971..11300)
                     /locus_tag="PC466_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HDF2769787.1"
                     /translation="MVPEMEEKVFSIISEAGDAKSDVMMSLKEIKKGDYNKAKHLLNS
                     ASEKIQTASKHHLELLSNAMNSEDSGTDFLVVHSEDHYSNALFAHSLVSELVDIFEMM
                     DPRINKN"
     gene            complement(11324..12613)
                     /locus_tag="PC466_002419"
     CDS             complement(11324..12613)
                     /locus_tag="PC466_002419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF2769788.1"
                     /translation="MEALQNNLRRFLLPIAQKIEKQRHLQAIKEGMISITPIIIVGSL
                     SMLFMALNNMLPEGSAKTLLSENMDTLLIPNKFTMSLLSIYSAFFIAQALAKKYNLNH
                     VEIGMTAVVAQLVVCGQVVDGVLDTSYLDAQGLFVSILVALLVVDITKFMNDKNLVIR
                     FPKEVPSVVNKSFRNLTPMIVCIMLFTAIAAITKNVSGQPLPAIIMNFLAPAISSVDN
                     VFAVTIILFITQLLWFFGLHGAAITSSIWMPIAATYMAENATLIAAGGDPKYVFTIGF
                     YYGFLQVTGSGITLGLVYLMSRSKCKSFNSMGKVVILPSLFGINEPVIFGTPIVMNPY
                     MFVPFVFGPVLVGALNFMALKVGLVGLPIAEPPGFLPPGVAAFLMTLDWKAIVLVFAS
                     IILMTLIYYPFFKIMEKEELNKNAELATTLDDDSFDF"
     gene            complement(12629..12955)
                     /locus_tag="PC466_002420"
     CDS             complement(12629..12955)
                     /locus_tag="PC466_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2769789.1"
                     /translation="MNILLVCANGASTGVLVEKMKSFCSEHEKLKTKTINIEATSFEN
                     LKSYIEANDTDVVLVAPQIRFKEDDVVEACKNYKIAVGLIDTKHYGRMDAPSVMKSAI
                     ELYKNR"
     gene            complement(13090..13719)
                     /locus_tag="PC466_002421"
     CDS             complement(13090..13719)
                     /locus_tag="PC466_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769790.1"
                     /translation="MQDKILRDKKANDPWARMTTRNGFSADEIISSFQKAIRRNMVEE
                     ACEFAYELYISSPELEDKLWRRILTISVEDIGMGDPSAVIIINNLNQVRKEYSYADGD
                     RPLFFIHAIRYLCACEKDRSSDLLKNIIIKGFAMGKVPEVMDVALDKHTYRGLEMGRD
                     SFHFLNEASIVIPEKEVDNDYKERYLKILEKYKQEEVIDTAFKFNHWQY"
     gene            complement(13934..14950)
                     /locus_tag="PC466_002422"
     CDS             complement(13934..14950)
                     /locus_tag="PC466_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDF2769791.1"
                     /translation="MVKAVGDIIGKCSAISFDMKLDKSYDEVIVDFKNLINNIDNKDV
                     LLFTDMGSLNSFDEIIKKEKKCEVRVIPMVTTLTVLEAVQKANMGLPLNDVYNSITNT
                     RKYYFGTNEIQNKENLSKTIIIASHVSEGVDNKTRKILEEKMSRYLDGIDIISVPYKT
                     EKDLSLNITKLKESSNIVAVINEQRINIRGIDYISKKDIDKDENINKLKNIIKISIGY
                     DDVVEGLKTSLKSSNYNRIFKDIKYVSDELFLVFNIEKKYDKVIGLMMHLAFMVDGLI
                     GNTREIEKLDKEKTLDYHKSLSKIKDIVSQLDKKYNIEINEKECYQILLILEYAEIIE
                     KDYQ"
     gene            complement(14931..16589)
                     /locus_tag="PC466_002423"
     CDS             complement(14931..16589)
                     /locus_tag="PC466_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2769792.1"
                     /translation="MIYKKDKVMKVLESSYRENEKGITANQLSEKTGIARNNISTYLN
                     QLFNEGMVTKIKGRPVYYIPANLNLNKNELLDTQSELLGIKKGTKVENKIKKDSFETL
                     IGKEHSLRPIIEKCKVAMLYPTNGLHTIIYGETGVGKSMIARYMYDYSIDSGIRKNKA
                     PFVTFNCADYANNAQLLMGHIFGVEQGAYTGAESSRKGLLEIANGGILFLDEIHRLPA
                     EGQEMLFTFIDKGTFKRLGDATKERDSKVLIICATTENPTSTLLDTFNRRIPMKIEIP
                     SLRDRTMIERMELVKNFFKEESKSISISIKVHKEIIKSLLLYDCKNNVGQLQNDIKLA
                     VANGYLRYKRDNKEPVYIEKKYFDKSINEVSDDYREKSIKADEVITHGIEYFVFTSLG
                     EEEVINYNDINIINAVNTNLNKSVEMNIADASLFNNVKFKSMCESIRQIIKEDEEIDI
                     SESIFKSMAIYIKSVLDKSSSTNNIDLNQIRRNNRSEFKTALKIVGIIENEFDLFLSI
                     ETVAYITLFIVQAKQDEQNKIVNNINIIVAMHGETTASNGKSSW"
     gene            complement(16948..17892)
                     /locus_tag="PC466_002424"
     CDS             complement(16948..17892)
                     /locus_tag="PC466_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009527644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2769793.1"
                     /translation="MNREKILEIKNLKQYFHLDKSTTVKAVDDISFDIYKGEIFGLVG
                     ESGSGKSTTGKTIIRLHESTGGEVIYKGNCISDKKTYKFIKKDVNKSMQIIFQDSTSS
                     LNPRMTIADIISEPLKIQGICKNKTDRMNKVYEMLKLVGLDRSYANKYPSDFSGGQRQ
                     RIGIARALSVDPEFIIADEPIASLDVSIQAQIVNLFKKLQQEKNLTCLFIAHDLSMVR
                     HISDRIGVMYNGKLVELADSNELYNNPIHPYTKSLLSAIPVPDPRYAKSRNRIEYNSN
                     GYDCSNEKSLSWIEVSDGHFVYSSKSEINKYQQNLKVV"
     gene            complement(17885..18910)
                     /locus_tag="PC466_002425"
     CDS             complement(17885..18910)
                     /locus_tag="PC466_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2769794.1"
                     /translation="MEHLLEVNNLSVSFKVEEGEVQAVRNVSFNLKKGETLAIVGESG
                     CGKSVLCKSLMRILPYNGYIKNGEVLLKSSDLVKKSEKEMEDIRGKNISMIFQDPMTS
                     LNPTISIGKQIAEAVIIHQGISKSEAKKRAIELIELVGIDNPEKRFKQFPHHFSGGMR
                     QRIVIAIALACNPDVLIADEPTTALDVTIQAQIIDLIKDLQHKIGLSIIFITHDLGVV
                     ATIADRIAVMYAGKIVEIGTVEDIFYDPRHPYTWGLLGSLPTLDSQDEYLYNIPGMPP
                     NLLNPPKGDAFAIRNKNALKIDYEKEPPMFKINDTHSAATWLLHPDAPEVDVPVRVNC
                     GRVISNE"
     gene            complement(18985..20553)
                     /locus_tag="PC466_002426"
     CDS             complement(18985..20553)
                     /locus_tag="PC466_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF2769795.1"
                     /translation="MKLKKLKVLSLVMILSLMAGCSSGGDKDKKADTPKDGKVLVYGS
                     NDYTSINPALYEHGEINSLIFNGLTAHDENNKVVPCLAKDWKFDEATNTYTFNLRDDV
                     KWHDGEKFTANDVKFTIETIMNPDNASEIASNYEDITKIDVVNDNTIKITLKAPNTAM
                     LDYLTVGVLPKHVLEGKDIATDEFNQKPIGTGPFKLEKWDKGQSITLVKNSDYFVKEP
                     GLDKVVFKIVPDDKAKAMQLKSGELDLAQITPKDMSNFEKDEKNFKVNIMKTADYRGI
                     LYNFNSKFFKDKKAKGLPNALSYAIDRKAIVDSVLLGHGVPAYSPLQMGPYNNPDIEK
                     FEYNPEKAKQEIEKLGWKLGSDGIYEKEGTKLAFEITAGESDQVRVDMAKICAQQLKE
                     IGVDAKAVVVTETDWANQDAHLIGWGSPFDPDDHTYKVFGTDKGANYSAYSNPTIDKI
                     LQKARETEDKDEKLKLYKQFQVEMTKDMPYTFIAYIDAIYVGKPNIKGLTPDTVLGHH
                     GVGIFWNIADWTIE"
     gene            complement(20666..21577)
                     /locus_tag="PC466_002427"
     CDS             complement(20666..21577)
                     /locus_tag="PC466_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2769796.1"
                     /translation="MKPQYSDFEIVGENYILVAEDEHIETKKTLSKKIKELPYISIII
                     LSIIVIGSVFSSFIMTHEPTYMDLASSNLAPNKTFLFGTDSMGRDIYSMIWYGGKISL
                     FIGLFSTVISTVIGIVYGSISGSASELVDDAMMRFTEIILSIPSILIIIFVQAILGNS
                     NPVSMSIVIGITSWMNISKIVRTEVRQIRNSEYILAAKSMGGGFFYVLKQHLLPNFVA
                     SIMFMVVTNIGAAIGTESTLSFLGIGLPIEIVSWGSMLSLSEEALLSNRWWIILIPGI
                     FLVTTLVCITNIGNYIRKNNNKKSSNL"
     gene            complement(21561..22547)
                     /locus_tag="PC466_002428"
     CDS             complement(21561..22547)
                     /locus_tag="PC466_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2769797.1"
                     /translation="MLKDILKKLLQFILVMFLLSFIVFYMARLAPGDPLISYYGDGVE
                     RMSTQEKENAMKKLGLNEPIYSQYIKWISNASKGEFGISFKYKQNVTSVINDVYINTI
                     ILGGSGYILTFVLALLLGIFCTLHEDKLIDRIICKLGTITNCIPSFWVALVLILIFSI
                     NLSILPSSGAYSMGEESSILSRISHLILPLTVLILSHLWYYTYMIRNKLLEEIREDYV
                     LLCKAKGLNNRTIVFKHCLRNIMPSYISIMAISIPHILGGTYVVEKVFSYPGLGTLCF
                     ESAKYHDYNMLLVLCLITGALVVFGNMLAQIINNKIDPRMKYDRGDTNEATI"
     gene            22906..23307
                     /locus_tag="PC466_002429"
     CDS             22906..23307
                     /locus_tag="PC466_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HDF2769798.1"
                     /translation="MLLKELYSKTMYTVEENFKENGLTHQQIIVIKLVAHNQELTISQ
                     LCDEMSLAKGTVSGIISRLEQIGYIEKFKKSNDKRNTYVKFTTTGFEFATNFKIKMQE
                     SFDDIFKNCDENELSDLVKNLRNILAKVKER"
     gene            23310..23708
                     /locus_tag="PC466_002430"
     CDS             23310..23708
                     /locus_tag="PC466_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03987 family protein"
                     /protein_id="HDF2769799.1"
                     /translation="MNYKLILAIVFITSALIFYTIGVFGERKAKILKKKHVIIFWLGF
                     IFDTLGTFTMSNIANSHTFEVKSALSQNLHSITGLLAIVLMLFHASWATFVLYKDDEE
                     KKKFFHKFSIVVWTIWLVPYFIGMFIGMVG"
BASE COUNT         7782 a         4075 c         2719 g         9316 t
ORIGIN      
        1 gggcttataa aagaatcttc tggtcaagta ttattaaata aacataactt gtctaattta
       61 gctgaacaca gaagaactca aatagtaagt agagtttttc aagacccaag tcttggaact
      121 tgcccttcta tgactgttag agaaaacttg tctttagctc ttaacaaagg aaaactatta
      181 aatctaagaa aatgtcttcg ttacaaaaga gatttcttag aaaatttatt ggaaggtgta
      241 tctcttgatt taaaaaaata ccttgatgtt caagtaaaat ttttatcagg aggtcaaaga
      301 caatcattat cactaattat gtcgtgctta acaagtccat cagttttatt acttgatgaa
      361 catacagcag cacttgaccc aaaaacatca aatgaagtaa ttgaattgac taataagatt
      421 gtaagggaaa aaaatataac tacacttatg gttactcaca acttaaaaca cgctcttcat
      481 tatggtgata gattgataat gcttcataag ggtgaagttg tattagatgt aaaaggtaaa
      541 gaaaaagaac aattaacagt tgaagaaatc ttagaaaaat ttgaatatgc agtttaaaat
      601 aatatatcta ttgtattaaa ctcggcttta aaataaagtt aaaattacaa taattatggt
      661 tactttgtaa taattcatat gaatatatga acatatataa taataaattt ttgaggggga
      721 tataaaaatg attaataaaa aaagattggc aagtttgatt ttagctggtg ctcttagtat
      781 atctatgctt acagggtgtt cacaaggagg agactctggt aattcaaaac aagaaagtaa
      841 ttctaaaggt aaagaagtta aaaaaattgg tataactcaa ctggttgaac atccagcatt
      901 agatgccact aggataggtt ttgtaaaagc attagaaaag aacggattta aagatggaga
      961 aaatattgat atagacttcc aaaatgctca aaatgacatg cctactacac aaagtattgc
     1021 gagtaaattt gcatctgata agaaggactt aatatttgct atatctactc catcagctca
     1081 ggcagcattt aatgctacta aagatatacc tatacttatt actgctgtga gtgaccctgt
     1141 tgctgctgga ttagttaaaa ctcttgaaaa gccaggcaca aatgtatctg gaacatcaga
     1201 ttttgtttct gtagacaaag gtttagaact tcttaaaata tttgctccta aggcaaaaac
     1261 tataggagtt atgtacaata ctagtgaagt aaattccaaa gttcaagttg atgctttaaa
     1321 agaatatgca tctaaaaatg gatttaaagt tgttgaaaaa ggtataacta cttcaaatga
     1381 agttaaccaa ggtatttcta gtttagttgg caaaatagac gtattatatg ttcctacaga
     1441 taacttagtg gcttcttcta tgcctatagt ctctaaaata gctactgaga ataaaatacc
     1501 tgttatagca gctgaatctg ggccagttga aaaaggtgct cttgcttgtc aaggtatcaa
     1561 ctacgaaaaa ctaggttaca aaacaggtga aatggcagtt aaaattttaa atggcgaatc
     1621 agtatctgat atgcctgtgg ctacatcaga tgatacagat atcattgtta atgaagatat
     1681 attaaaagct ttaggtatgg aaaaaccttc taatgaaaat atttcttatg taaagactaa
     1741 acaagaatag aaagatattt tctatatacg attaatatgc ctgtttctat aaattaattt
     1801 atagaaacag gcatatattt ttattttaat gtattatcta tttaaagatt atatgtaaat
     1861 gctcttaata tgattgtata aattttactt gtataaactt tatacaatca tatttattct
     1921 tctattttct ttattactct acatggattt ccaacagcta cagtatttgg tggtatatct
     1981 tttgtgacta cacttcctgc acctattact acattatcac ctatagtaat tcctggtgtt
     2041 atgattactc ccccacctat ccatacatta tcacctattt ttacaggaga accatactct
     2101 atgcctgaat ttctaagttg tgcatcaatt ggatgatagg ctgtatagat ttgaacgttt
     2161 ggagctaaca ttacattgtc acctatttca attttacata catctaaaaa aatacaatca
     2221 taatttgcaa agaaattttc gcctacatgt atgttatatc cataatcaca cctaatgttt
     2281 tgttctacat ttatttgctt gccaactgaa ccaaatagtt gtcttaaaat atcttctctt
     2341 ttttcatatt catcctctaa agtattatta aacaatctag ttaatttttt acaatactct
     2401 ctttctttta ctaacaattc atcatttgca tagtatcctt ttccagacaa cattttttct
     2461 ttttcagtca tatagtttac tcctttttgt tataattgta tctaaagcaa aataaatatt
     2521 cctgtggaaa atctaaatat attctgtcac ctttcttaaa tctcatttta cttttttcca
     2581 attctatttg aataggtaca cattcgttag ataaatcagt ttttctaaca tatatagtat
     2641 atgtaaaagg attttctaca atgttaatca attcgaaaca taacttttca tttaaatctt
     2701 cattagaatc caagacctta atatgatgct ccctgattcc cacatattct atattatcac
     2761 ctatttctct atttaatgtc aactcgcatc cccagtctgt agcataaata gtatttttat
     2821 ccagtctatt taatttggat atatttttac accctgttat cttagcttct ataaggtact
     2881 ttggagattc aaagagctct tttttaggtc tctttggaag accttctcct ttgttgtaca
     2941 ctataatatc atcacaaact cggtaagctt cttcaatatc atgagtaaca aatagtatat
     3001 ctcccttgta atcttttaac atattcataa gttctttttc catattactt cttaaatgat
     3061 ggtccagtgc tgagaaaggt tcatctaaaa gtaatatatc tggagatgtt gccaatgctc
     3121 tagctagtgc taccctttgt tgttgaccac cagataattg ccaaggatat ctcccttcaa
     3181 acccatttaa tttaagtata tctaagtacc ttgctactat ttcctttttt tcactcttac
     3241 ttagttttaa aagcccaagt tctatatttt gacttacagt catatgtgga aacaaagcat
     3301 agttttgaaa taaaaatcct acctttctat cttgtgttga taaatttatc ttcttttcag
     3361 aatcaaatag aactctatca tttaatacaa ttttacctct tgttggtttc tcaagccctg
     3421 ctatacattt taatgtcata ctttttccag aaccagattc ccccaaaaac cccagagtac
     3481 ctttttcttg tttaatttct acctttagtt taaaagagga taaatctttt tcaatatcca
     3541 cgtataagct caactatcca cacctctttc ctataatttt ttgctgaaat tccgaccaat
     3601 aatttagtaa taaaatcatt gctatagata ttgctacaat aatcataacc cacatcatag
     3661 ctttattcat atctccgcct tcaacagcaa aaaatatagc tattggcata gtttgagttt
     3721 ttccaggtat atttccagct atcataagtg tagcaccaaa ttcgccaaga gctctggcaa
     3781 acgacagcac caatccacca attattccag gccatgctaa tggaactgca atcttaaaaa
     3841 atactttcca ttcattaaga cctaatgttc tagcagctga cagcatatta ttatcaatct
     3901 gttcaaaagc tgaccttgaa gttctataca tcataggaaa agacaccact actgctgaaa
     3961 ttacagttgc tgtccaacta aatattaaag tcctatcgaa atttaataaa aactttccta
     4021 taaatccatt cttcccacat agtaataata aaaagaaacc tacaactgtt ggtggcaaaa
     4081 ttagtggaag tgtaaatagt ccatctataa gacccttcca cttacctcta tagttagcca
     4141 taatatatga cacaaatatt cctattacaa aagttattat tgttgacaaa atagatgtct
     4201 taagtgatat ccataagggt gaccaatctg ttcccatctt tccctcctta attttaaatg
     4261 gaaatagtga aactaataac tctattaatt tcactatttc cattttatta taatacacaa
     4321 ttattttcaa ttttcattta tttatatata atttatactt aattacacat aatttattta
     4381 taagtttatt ctactttttt atatccaaat tcttcaaaaa tcttttgtcc tgactcactt
     4441 aataaaaatt cttcaaattt cttagcagca tctacgtttt tactagcttt aattactgaa
     4501 actggatatg taataggtga atgagttttt tcgtctgttt tttcaactac ttttatctta
     4561 tcattattga cagtatcact gaagtaaacg aatccaacat cagcatttcc tgattgcacc
     4621 catgctaaaa cttcttttac atcttttgca aatactagct tatcttttaa cttatctttt
     4681 aaatttaaat tagttaacac ctcatctgca tacttaccag ctggaacact ttcaacttca
     4741 ccaacagcaa ttttcttcac tttatctgta gtcaaatctt tcatacctga tacactactg
     4801 tcagcagaag aaataagaac taaatcattt tttactaaat ctttcatagt atcagaaact
     4861 aataacttct cttcatccaa agctttcatt tgtttttgac ctgctgaaat aaataaatca
     4921 caaggtgctc cttgttctat ttgttgttgt aatgagcctg atgctccata gttaactgta
     4981 agttttacat ttgaatcaac ttttttatat tcttcttcaa tctttgccat tgcttctttt
     5041 aaacttgcag cagccgatat atttaactct actgaatcac tacttttagt tgttttttct
     5101 tgttttccat catctgtttt gtcttcatta ctattgcacc caactgtccc caaagttaaa
     5161 catgcaacta atcctaatat tcccaatatt tttttcataa caatctccct ttttgtaaat
     5221 ttgatacaca ttttaatatg ttttattatg ttttatcatg ttttgttata tatagtttaa
     5281 ttatatatac atgataataa attttcaagt aatttattta cactactttt aaatattttg
     5341 ctacattttc ctttttttaa tgttaaaata accttatatg gaggtggatt atggactcat
     5401 tatcatcttt gacacctgtc gaggtagctg aattattaaa gataacaaaa aatactgtat
     5461 atgaattaat caaaagaggt gaacttcctt cttataaagt agggaaaaaa ataagagttg
     5521 atactaaaga tgttgaagaa tatatcaaca gccaaaaaac tggtaaagta aaggatacac
     5581 atttcaacaa taaaaatata gatataaata ataatttcaa aattattatt tctggtcaag
     5641 atgtaatatt agacatttta gctaggtctg ttgaaaaaaa attggatgga ataagtacat
     5701 ttcgctctta tataggtagt tataatgctt tgtatgagtt atataatggc agagtttcta
     5761 tagcatcatc ccatctatgg gatttcgaaa cggatgaata taatagcact tttgttaaaa
     5821 agctattgcc aggaatacca tgtgtactta taaatctagc ttatagaatg caaggtttct
     5881 atgttgctaa aggaaatcct aaagagataa caacctggga ggatttaaca aaaccaagta
     5941 taaccattgt aaatagggaa aaaggttctg gaactagggt tttactagat ggtaaactta
     6001 gacttctaaa ctttaatggt aaacatataa aaggttatga taatgaagaa ttatcacatc
     6061 ttggagttgc aagtactgtt tctcgtggaa tagctgatgt tggtttggga aatgaaaaag
     6121 ctgctttaca agtaaataat atcgacttta ttcctcttca caaagagcgc tatgatttag
     6181 ttattaaaaa agaagactta caaaatccag tttaccaaac tataattaac ataataaact
     6241 ctcctgagtt taaagctgaa cttcaaggtc ttggcggata tgatttaact gatactggaa
     6301 aaactatagc aaaagtttaa gattaaaatc gcaatctatt ttataagatt tataattttt
     6361 cacaaaattt ataacttaaa cacgaaataa attgcgattt tagtgtctca aaaaatttat
     6421 gtctttcatt ttatcatcca atacaaaata taatataatt aattgtgcaa tcatattata
     6481 ttaatatata tttacataat agtatttttc tttaatgtag attaacatat gatatgtttt
     6541 aaacatcaac acccttgctt tcttatatat atgtggcaac acatatgagt ttaataaatt
     6601 atatacaatg ttgctttctt cttgtatttt ttcaaccaac aagttattta taaaattacc
     6661 tttctcattt tcaataatct cactccaatt tatcttaact tttaatatat atcttcccac
     6721 taggtataca cactctacaa taaataataa aaatacaata cagtcagtac ctgttgtctt
     6781 atataaatta cccgatacta atggctttgc gaagaaatta taaaaattca aagtatcacc
     6841 cgtataatca aaaagtatta atagcactcc tagaactctc aatactttaa tattcaacat
     6901 gtttttatct ttattatttt tgtttttcat atatactacc tctcttttct ttagatttga
     6961 ttgtaatcta atactaactc ttttatttga ggtataaatg aatttaattg gtagttattt
     7021 tcatttttac tagaaattaa ttcacattac taaacaaaac ttatatttaa acataaaaat
     7081 agcctatcta ttttttaata aatacaaaaa taaataagct actaatattc aattaacttt
     7141 tatcacttaa aacattacta tctataaatt taaatatttt attgaagtat actgtactat
     7201 catgttcaaa tccatcaaca tgaccaatac cttctataag ccataggtct tttttatcat
     7261 gtttaactaa atcatacatt ttcttgctat tttgataatt acaaacagta tcttttgttc
     7321 catgtataaa cagtatgggt acattagatt tctcaactga ctcatatggt tttacatcac
     7381 tgtaccaaaa tccagattta aacttattat ataaatctcc acaaatcacc acataattga
     7441 ttaatatatc tggtattcgt ttttctagta ctcccattct aattgcatct ttcatttcag
     7501 aataaggaga atccagtata taaaaatcga ccttatcatc ttttgaattt atctctgaat
     7561 gcatagcagc tgtccctgct cccatggaaa atccatgcac tcctaatctt ccttcaggaa
     7621 atttattttt tacaaattta actagactat ctaaatcata cctttcataa agaccaaatg
     7681 tgtaattatc tccaccacta ttaccagtat ttctttgatt ataaactaat acattataac
     7741 ctttatctaa atatctatat gctaccttta acatttcata gtaactactt ccaattccat
     7801 gaacaagtat catagtatct cttgtcttta tatttgaagt tataaaaaga ctttcaagct
     7861 tgtaattatt agaactttgt atcattaatt cagatgtctt gtagtttttt aatttctcca
     7921 gtggtttatc ttttctctca gaaaatattt ttactatatc ttcgtttttt attaactgct
     7981 ctaaaccaac cgaactatta tacactaatt tgccaaatat ataagataca attaatagga
     8041 ttaatagaaa cacaattgat ataattataa atttatttct taaactaata caatttttaa
     8101 aactattttt catatttatt taccatacaa ttttcctata ttatattttc taagtaatag
     8161 cataattgat tatactattc ttataatttc tattatacct acttatttat taaaaataca
     8221 aattatattt tattaatttt tactacttgt aaattattat cttatacaat gaatttgtat
     8281 tatataataa gtatttttag gattctgtta cataatatta tttaaatatt cttctatatt
     8341 tctcttcttc ttcttcagta aacacattaa atacaacttt taaatttttt tcaggatttt
     8401 cttttagcca tagtctaact ctacttacag caagattagc tgcctctttt tttggataac
     8461 caaatacacc tgtagaaatt ccacaaaaaa caatattttt tatttcatca atttctttta
     8521 ttgtatttaa acatgattta taacaatgaa gcagttgctt ttcttgctct ttacttggct
     8581 gaccaccaga tacaataggt ccaacagtat gtactacaaa ttttgcaggt aaacaatagc
     8641 ctctagttat cttagcatct ccagtatatt ctaaatgccc ttgttttttt attattttgt
     8701 cacaatcttc tctaagtcta ggacctgcgc atgaatgtat ctcattatcc acgcatagat
     8761 gtaatggttg taaacaccct aataacttgt tatttgcagc atttactatt gcatctgctc
     8821 ttaaattcgt tatattacct ctccatatgg caatcccttc ctctacttct tctatatcat
     8881 ttacatctac taactctctt tcttcacatt caatcaacaa taaattatgt aacatattaa
     8941 gtatctctgg agcaatttct tttggtggat atacattcaa aagtcctcta agtatatctc
     9001 taggcttaat ttcatcattt gataaattgt atattttaga aggaacttct tttgaaaaat
     9061 atgcaattaa agtgtttata ttttttcttc tttgttcgtc agttagaggc ttgatagttt
     9121 tatcaaaatc ctcaaataaa tttacatcat cagcataatc tctccacttc atagccatct
     9181 ctccattctt gtattttaga cttaaaaata attatgtatt tatgtacata tttatttatt
     9241 tctataaaca cctacataaa tcctgttaaa agtgtaaatt ttttattatg caacttctct
     9301 ggttatttct attgattgat agtaaattat tgtacctaaa tttaatccaa ctaacaagta
     9361 actaaaccta ctttcctaac tgcaaaatac actatgtttg ccacttgtat ctcatttgta
     9421 aataaataaa gtccctacaa atacattaac taggctatgt actaaactgt aggaacttta
     9481 aaaatatatt attcttaatt aagttttggc caataatttt tatttgcttc tattaaatca
     9541 tctagtaatt cttttgcaac tgttgcacta ggaactgtct tagatagcat aagtgcttgc
     9601 cacaatttat tataagactt ctcaatccaa gcatcaacta ctaatttttc aactgctaat
     9661 tgttgttcta ttaaaccttt ttggaatgtt ggtattttcc ctattgataa tggttcatac
     9721 ccgtcttttc caactataca tggaatttca accatagcat catcttgtat attttctata
     9781 gctccattat tttgaactat caataacata cgctcctgtg tattaaaagc tagagctgta
     9841 gctaaatcca ctataaactc tgcatgtatt cctatcttaa gcccactgcc cttagaatgt
     9901 ccttgctttt ctatcaatgc acatgaacca aaaacttctt tttctcttcc atcaataact
     9961 tcattggcac gagtataatt tacatcagaa tgatttacaa cataatctgg aaatagatag
    10021 tactttaagt aactacttgg tattgtagtt aaatctgttt ttactatttc tttagtaaat
    10081 aaattagttt caaaccaact atctttcttg tcatttttca ttccttcttc accatttata
    10141 aaaccatatt cttttatatg ttctactaat tttggtaaaa gttcatttcc ttttttatct
    10201 ttaattgaag tataccaacc aaagtgattt aatccaaagt atcttatatc catatgttta
    10261 cgagatttga gtcctgcaat ccttgctata ttatgttcca tacctattgg catatcacaa
    10321 atatttatta ccctagaatt aggtctcaac cttctaacag cttccgctat tattgatgct
    10381 ggattagaat aatttaacat ccaacaattt ggagaatact tttccatata atctatgttt
    10441 tcaagaacac cttctataga cctcattcca taagctattc cacctggtcc acaagtttct
    10501 tgaccaacta ctccatgttt tagaggtatc ttttcatcta gttctctcat ttcaagtttt
    10561 ccaactctta tatgagctaa acaaaaatct acatctgtat aagcctcttt agggcatgtt
    10621 gttgctaaat actctatatt agggtccttt tcctttatta gtatttcaca agctttagct
    10681 accttatttt gtctttcttc atcattatca tataatttga ttgctcttaa tggtaaccta
    10741 tctaagttat ctagcaacat taatatgatt tctggggtat atgtacttcc tcctccagct
    10801 attactactg aaaatttttc cataataata tctccttttc tatttaaaaa tttactgtat
    10861 ttataaataa atttataaat actagtactt taaagtaaaa gggagttcat ttattaaatc
    10921 tattgattta ataaactata gccaaacttc aagcactatt tacaagaaat ttaattctta
    10981 ttaattcttg ggtccatcat ctcaaatata tctacaagtt cagatactaa agaatgagca
    11041 aataatgcat ttgaataatg gtcttcagag tgcacaacta aaaaatcagt cccactatct
    11101 tcactattca tagcatttga tagtaattct aaatgatgct ttgatgctgt ttgtattttc
    11161 tctgaggctg aatttaaaag gtgttttgct ttattgtagt cacctttttt tatttcctta
    11221 agagacatca ttacatcact tttagcatct cctgcttctg atattatact aaatactttt
    11281 tcttccattt caggtaccat atccttctcc ttctaatgac ttgttaaaaa tcaaagctat
    11341 catcatctaa tgttgtagct aattctgcat ttttatttaa ttcttccttc tccattatct
    11401 taaagaatgg ataatatatc aaggtcataa gtattatact tgcaaatact aatacgattg
    11461 ccttccaatc taatgtcatc aaaaatgctg caacccctgg aggtaaaaag cctggtggtt
    11521 ctgcaatagg taatcctact aatcctactt ttaatgccat aaaattaagt gctccaacca
    11581 atacaggtcc aaatacaaat ggtacaaaca tatatgggtt cataactatt ggtgttccaa
    11641 atattactgg ctcatttatt ccaaatagtg atggtaaaat cacaactttt cccatactat
    11701 taaaactctt acacttactt cttgacataa ggtacactaa tcccaaagtt atccctgaac
    11761 cagttacttg caagaaacca tagtaaaatc ctattgtaaa cacatatttt gggtctcctc
    11821 ctgctgctat cagtgttgca ttttctgcca tatatgtagc tgctattggc atccatatac
    11881 ttgaagttat tgctgctcca tgaaggccaa agaaccataa taattgagtt ataaatagta
    11941 ttatagttac tgcaaaaaca ttatctacac tgcttatagc tggtgctaag aaattcatta
    12001 taatagctgg taatggttga cctgagacat ttttagttat tgctgctatt gctgtaaata
    12061 acattataca tactatcatt ggagttaaat ttctaaaact tttatttact acactaggta
    12121 cttcttttgg aaatctaatt acgagatttt tatcattcat aaacttagta atatcaacta
    12181 ctaaaagtgc tactaatata cttacaaata aaccttgtgc atctaaataa cttgtatcta
    12241 atacaccatc tactacttgt ccacatacaa caagttgtgc aacaactgct gtcataccta
    12301 tttctacatg attaagatta tattttttag ctagtgcctg agctataaaa aatgctgaat
    12361 atatagataa taaactcata gtaaatttat tagggataag taatgtatcc atattttcag
    12421 ataataatgt ttttgcactt ccttcaggta acatattgtt taatgccata aataacatac
    12481 ttaaagaacc aacaattatt attggggtaa tgcttatcat accttctttt atagcttgaa
    12541 gatgcctttg tttttcaatc ttttgtgcta ttggtagaag aaatcttctt aaattatttt
    12601 gaagtgcttc catttttatt ccccccaatt atctattttt atataattcg attgccgact
    12661 tcataacaga aggagcatcc atacgaccat aatgcttagt atctattaaa ccaactgcta
    12721 ttttgtaatt cttacaagct tcaactacat catcttcctt gaacctaatt tgtggtgcta
    12781 caagtactac atctgtatca ttagcttcaa tgtatgattt taaattttcg aatgatgttg
    12841 cctctatatt tatagtttta gtttttaact tttcatgctc actacaaaaa cttttcatct
    12901 tttccacaag tacacctgtt gaagctccat ttgcacatac taataaaata ttcataatta
    12961 ccctcctaca atatctaacc tcttttattt tctaattttt tatcagccaa ttcttactct
    13021 aattcctatc agtttttact ttaattctta ttattttatt ttaattctta ttaatattta
    13081 ctctaattct tagtactgcc aatgattaaa cttgaaagcc gtatctataa cttcttcttg
    13141 cttatatttt tctaatattt ttaagtatct ttctttataa tcattatcta cttctttttc
    13201 tggtattact atactagctt catttaaaaa gtggaatgaa tcccttccca tttctaatcc
    13261 tctatatgta tgcttgtcaa gtgccacgtc cataacttct ggaactttac ccattgcaaa
    13321 tccttttata attatatttt ttaataaatc acttgatcta tctttctcac atgcacaaag
    13381 atatcttatt gcatgtatga aaaataaagg tctgtctcca tctgcatatg aatattcctt
    13441 tcttacttga tttaaattat ttatgattat tacagctgat gggtccccca ttcctatatc
    13501 ttcaactgat attgtaagta tccttctcca tagcttatct tctaattctg gtgatgatat
    13561 atatagttca taagcaaatt cacaagcttc ttccaccata tttcttctta tagctttttg
    13621 aaatgacgat attatttcgt ctgcactaaa tccgtttctt gtagtcattc ttgcccatgg
    13681 gtcatttgcc tttttatctc ttaatatttt atcttgcata ttatttactc ctttttattt
    13741 aaattttaat tatttatatt actcatttaa taatataagc aagtattatg ccagtttttt
    13801 tagacacttt aaaacactgt tatttcaatc atttttatca tcaaaactta gatactttgt
    13861 ctaagtatat ttatatgtgt ctaatattaa tattatttta gactaaaaaa aattaccaaa
    13921 taagttttta tactcattgg taatcttttt cgattatttc tgcatattct aatattaata
    13981 atatttgata gcactctttt tcattaattt ctatattata ttttttatct aattgagata
    14041 ctatatcttt tattttgctt aggctcttgt gataatcaag tgttttttct ttatcaagct
    14101 tttcaatttc tctagtattt ccaatcaacc catctaccat gaaagctaaa tgcatcataa
    14161 gtccaattac tttatcgtat ttcttttcta tattaaatac taaaaacaat tcatcagaca
    14221 catattttat atctttaaat atcctattat aattagagct ttttaaggat gtctttaaac
    14281 cttcaactac atcatcataa cctatactta tctttataat attttttaat ttattgatat
    14341 tttcatcctt atctatatct tttttgctaa tatagtcaat tcctctaata ttaattcttt
    14401 gttcattgat tactgcaaca atattactac tttctttaag ttttgtaata tttaaactta
    14461 aatctttttc tgttttatat gggacagata taatatctat tccatctaag tacctactca
    14521 tcttttcttc taatattttt cttgttttat tatctacacc ttctgaaaca tgtgatgcta
    14581 taataattgt tttagacaga ttttctttat tttgaatttc attagttcca aaataatact
    14641 ttctcgtgtt agtgatagag ttgtatacgt catttaaagg taatcccata ttggccttct
    14701 gaactgcttc taacacagtt aatgtcgtca ccataggaat tactcttact tcacactttt
    14761 tttctttctt tataatttca tcaaaggagt ttaatgaacc catatctgta aatagtaata
    14821 catctttatt gtctatatta ttaattaaat ttttaaaatc tacaataact tcatcatagc
    14881 ttttatctaa cttcatatcg aaagaaatag cactgcactt tccaataata tcaccaactg
    14941 cttttaccat tacttgctgt agtttctcca tgcatagcaa ctataatatt aatgttattc
    15001 actattttat tttgttcatc ttgtttagct tgtactatga ataatgtaat atatgctaca
    15061 gtttctatag ataaaaataa atcaaattca ttttcaatta ttccaactat ttttagtgct
    15121 gttttaaatt cacttctgtt atttcttcta atttgattca aatctatgtt gtttgtagag
    15181 ctacttttat ccaatacgct ttttatataa attgccattg acttaaatat tgattcactt
    15241 atatctattt cttcatcttc tttaataatt tgtcttattg attcacacat gcttttaaac
    15301 ttaacattat taaatagaga agcatctgct atattcattt ctacagattt attaagatta
    15361 gtatttactg cattaataat atttatatca ttgtagttaa taacttcttc ttctcctaat
    15421 gacgtaaata caaaatattc tattccatgt gttataactt catctgcttt aatagacttc
    15481 tctctataat catcactcac ttcatttata gatttatcaa aatatttttt ctctatataa
    15541 actggttctt tattatctct tttatatctt aggtatccat ttgcaacagc taattttata
    15601 tcattttgaa gttgacctac attattttta caatcataaa gtaatagtga tttaattatt
    15661 tctttatgta cttttattga aatagaaata ctttttgatt cttccttgaa aaaatttttg
    15721 actaattcca ttctttcaat cattgtccta tctctcagtg atggtatttc tattttcatt
    15781 ggtattcttc tattgaatgt atctaatagt gttgatgtcg gattttctgt agtagcacat
    15841 attattaata ccttagaatc tctttctttc gttgcatctc ctagtctttt aaatgttccc
    15901 ttatctataa aagtaaacaa catttcttga ccttctgctg gtagtctatg aatttcatct
    15961 aaaaatagta tccctccatt tgcaatttcc aaaagacctt ttctggaaga ttctgcacct
    16021 gtataagctc cttgttctac tccaaaaata tgtcccataa gtaattgtgc attattagca
    16081 taatcagcac aattaaatgt tacaaaagga gctttatttt ttctaattcc actatctata
    16141 gaataatcgt acatatatct agcaatcata ctctttccta ctcctgtttc tccatagata
    16201 atagtatgaa gtccatttgt aggatagagc attgcgacct tgcatttttc tattataggt
    16261 cttaaactat gttctttacc tattagtgtt tcaaaactat ctttttttat tttgttttct
    16321 acttttgttc ctttttttat gccaagcaac tcactttgtg tatcaagcaa ttcattcttg
    16381 ttaaggttaa gatttgcagg gatataatac acaggtcttc cttttatctt cgtaaccata
    16441 ccctcattga ataattggtt taaatatgta cttatattgt ttcttgcaat tcctgtcttt
    16501 tctgataatt ggttagctgt aatccctttt tcattttccc tatatgatga ttctaaaact
    16561 ttcattactt tatctttttt atatatcatt acaagctccc ctacattata atattttatt
    16621 aactaaaacc cctatacaca ctttattttt taataaactc ttattcttta actaaggtta
    16681 taatttatca aactttcctt actttaaatt atagaaaatt attgtagaaa aaataagatt
    16741 attgctcatt ttttctacat tactattttt aattttatag cactttctta acaacatact
    16801 ttacttgttt ttaattttat tatatttgaa tttattatat ttgaaaagta gaaataaaaa
    16861 accctatttt ggagtagttt taaaatttct ccaaaaatag ggttttagtt tgtatttcaa
    16921 ataaatacct gttcaagtat ttttatacta aacaactttt aaattttgtt gatatttatt
    16981 tatttctgat ttagaagaat atacaaaatg tccatctgaa acctcaatcc aacttaatga
    17041 cttttcattt gaacaatcat atccattaga attatactct attctatttc ttgacttagc
    17101 atatctaggg tcaggaacag gaattgcaga aagtagtgat tttgtatatg gatgaatagg
    17161 attattatac aattcatttg aatctgccaa ttctactaat tttccattat acataactcc
    17221 tatacggtca ctaatatgtc tcaccataga taaatcatga gctataaata aacaagttaa
    17281 attcttttct tgttgcaatt ttttaaataa atttactatt tgtgcttgta tagacacatc
    17341 caaagaagct ataggctcat cagctattat aaattctggg tctactgaaa gagctcgtgc
    17401 tatgccaata cgctgtcttt gtccacctga aaaatcagat ggatacttat ttgcataact
    17461 tctatcaagt cctactagct ttagcatctc atatacttta ttcattctat ctgttttatt
    17521 tttacagata ccttgaattt ttagtggctc tgaaattata tctgcaattg tcatacgtgg
    17581 atttaatgat gaagtagaat cttgaaaaat aatctgcata cttttgttta catctttttt
    17641 tataaatttg tacgtttttt tatctgatat gcaatttcct ttgtaaatta cttctccacc
    17701 agtagattca tgtagtctta ttatagtttt accagttgta gattttcctg aacccgactc
    17761 tcctaccaat ccaaatatct cacccttata tatatcaaaa cttatatcat caactgcttt
    17821 tacagtagta cttttgtcca aatgaaaata ttgctttaag ttttttattt ccagtatttt
    17881 ttctctattc attagaaatc acccttccac aatttactct aactggtaca tctacttcag
    17941 gtgcatctgg gtgcaataac caagttgctg cactatgtgt atcattaatt ttaaacattg
    18001 gtggctcttt ttcataatct atcttaagtg catttttatt tcttattgca aaagcatctc
    18061 cttttggtgg gttcaataaa tttggaggca ttccaggtat attatataaa tattcatcct
    18121 gtgaatctaa agtaggtaat gaacccaaca acccccaagt atatggatgt ctagggtcat
    18181 aaaatatatc ctctacagtt cctatttcta caatctttcc tgcatacata actgctattc
    18241 tatcagctat agttgcaact actcctaaat catgagttat aaatattatt gacaaaccta
    18301 ttttatgttg taaatccttt attaaatcaa ttatttgagc ttgtatagtt acatctaaag
    18361 cagttgtagg ttcatcagca atcaatacat ctggattaca ggcaagtgct atagctatta
    18421 ctatacgttg tctcattcca cctgaaaaat gatgtggaaa ttgtttaaat cttttctcag
    18481 gattatcaat tccaaccaat tcaataagct ctatggctct cttttttgct tcacttttac
    18541 ttataccttg atgaatgatt acagcttctg caatttgctt tcctattgat atagttggat
    18601 tgagagatgt catagggtct tgaaatatca ttgatatatt ctttcctctt atatcttcca
    18661 tctctttttc agacttctta accaaatcac ttgatttaag taaaacctct ccatttttaa
    18721 tatatccatt gtatgggagt atcctcatca aactcttaca cagtacagat ttcccacaac
    18781 cagattctcc aactatagcc aatgtctcac ctttttttag attaaaagat acatttctta
    18841 cagcctgaac ttctccttct tctactttaa aacttacaga tagattatta acctccaata
    18901 aatgttccaa aaaccatcaa cccctatgct attcaaacct tagggatata tttttatccc
    18961 taaggtttct aattaatttc agtattattc aattgtccag tcagctatgt tccagaatat
    19021 acctacacca tgatgaccta aaactgtatc aggtgttaat ccttttatgt ttggttttcc
    19081 aacatatatt gcatctatat aagcaataaa tgtataaggc atatccttag tcatttctac
    19141 ttggaattgt ttatataact ttaatttttc atctttatct tctgtttctc ttgctttttg
    19201 aagtatttta tctatagtag gattagagta agcactgtaa tttgcacctt tatctgttcc
    19261 aaatacttta tatgtatggt catctgggtc aaatggactt ccccaaccta ttaaatgagc
    19321 atcttgatta gcccaatctg tttcagttac aacaacagct ttagcatcaa caccaatttc
    19381 ttttaactgt tgtgcacata ttttagccat atcaactcta acttggtcac tctcacctgc
    19441 tgttatctcg aaagctaact tagtaccttc tttttcatag attccatcag aacctaattt
    19501 ccaacctagc ttttcaattt cttgtttagc tttttctgga ttatattcaa acttttctat
    19561 atcaggatta ttatatggtc ccatttgtaa aggtgaatat gctggtacac catgtcctaa
    19621 taatacactg tcaactattg cttttctatc tattgcatag cttaaagcat ttggtaatcc
    19681 tttagctttt ttatctttaa agaatttaga attaaaattg tataatatac ctctatagtc
    19741 ggctgttttc attatattta ctttaaaatt cttttcgtct ttttcaaagt tagacatatc
    19801 tttaggagtt atttgagcta agtctaattc tcctgatttt aattgcattg ccttagcctt
    19861 atcatctgga acaatcttaa agactacttt atctaatcct ggttctttta caaaataatc
    19921 actattctta acaagtgtta tactttgacc tttgtcccat ttttcaagtt taaatggtcc
    19981 agtacctatt ggtttttgat taaattcatc agtagctata tccttacctt ccaaaacatg
    20041 ttttggtaat actcctactg ttaaataatc aagcattgct gtatttggag cttttaaagt
    20101 aatttttata gtattatcat taaccacatc aatttttgtt atatcttcat aatttgatgc
    20161 tatctcagaa gcattatctg gattcattat agtttctatt gtaaacttaa catcatttgc
    20221 cgtaaatttc tctccatcat gccacttaac atcatctctt aaattaaaag tatatgtatt
    20281 tgttgcctca tcaaatttcc agtcctttgc tagacaagga accaccttat tattttcatc
    20341 atgagctgtt aatccattaa atattaatga atttatttct ccatgttcat atagtgcagg
    20401 atttatactt gtatagtcat tacttccata aacaagtacc tttccatctt taggcgtatc
    20461 tgccttctta tctttgtctc ctccactaga acaacctgcc attagactaa gtatcattac
    20521 taaacttaaa acttttaact tctttaattt catgatgctc ccccttttgc tttttataaa
    20581 atatttttca aagctttgac cccatttatt taaatagata tttcaaatac ctcagtattt
    20641 gcttatttag tactcaaatg ctgatttata aattactaga ttttttatta ttattctttc
    20701 ttatataatt acctatattt gttatacaca ccaatgtggt aaccaaaaat atacccggaa
    20761 tcagtataat ccaccatcta tttgaaagta atgcttcctc tgacaaagat aacatacttc
    20821 cccaagaaac aatttctatt ggtaaaccaa ttcctaaaaa gctaagtgtc gattcagtac
    20881 caatagctgc gcctatgttt gttacaacca tgaacattat tgatgccaca aaatttggaa
    20941 gtaaatgttg ctttaataca tagaagaatc ctcctcccat gctcttagct gctagtatgt
    21001 attcgctatt tcttatttgt ctaacttctg ttctcactat cttagatata ttcatccaac
    21061 ttgttatccc tattactatg gacatagata ctggatttga atttccaagt atagcttgta
    21121 caaatattat aattaatatt gaaggtatac taagtatgat ttctgtaaac ctcatcattg
    21181 catcatctac gagttcagat gctgaaccac ttatactacc ataaacaatt cctataacag
    21241 ttgatattac agtggaaaat agtcctataa ataaagatat ttttcctcca taccatatca
    21301 tagaatatat atctctaccc attgagtctg ttccaaataa aaaagtttta tttggagcta
    21361 aattagaact tgctaaatcc atgtatgttg gttcatgtgt cattataaaa gatgagaata
    21421 cacttccaat gactatgatt gataaaataa taattgatat atatggtaat tctttaattt
    21481 ttttagataa ggttttcttt gtttctatat gttcatcttc tgctactaaa atataatttt
    21541 ctcctacaat ttcaaaatca ctatattgtg gcttcattag tatcacctct atcatatttc
    21601 attctagggt ctattttatt gtttataatt tgagctaaca tattcccaaa tactactaaa
    21661 gcccctgtta ttaagcataa aactaataac atattataat catgatactt tgcactttca
    21721 aaacaaagtg ttcctaaccc aggataagaa aaaacttttt caactacata agttcctcct
    21781 agtatatgag gtatcgaaat ggccattata ctaatatatg atggcattat atttctcagg
    21841 caatgcttaa aaacaatagt tctattattt aaaccttttg ctttacataa aagcacataa
    21901 tcttctctta tttcctctag taatttattt cttatcatat atgtgtaata ccatagatgg
    21961 cttaatataa gtactgtaag aggtaagatt agatgtgata tcctacttaa tatactggac
    22021 tcttctccca ttgaataagc accactactt ggaagtatac ttaagtttat actaaatata
    22081 agtatgagta ctaaggcaac ccaaaatgat ggaatacagt tggttattgt tcctaatttg
    22141 catatgattc tatcaatgag cttatcttca tgtaatgtac aaaatattcc taacaataag
    22201 gctagcacaa aggtaagtat ataccctgaa ccacctaata ttatagtgtt tatatagaca
    22261 tcatttataa cagaagtaac attttgttta tatttaaatg aaattccaaa ttcccctttt
    22321 gatgcatttg aaatccattt tatatattga ctgtatattg gttcattcaa accaagtttt
    22381 ttcatagcat tttctttttc ttgtgtactc attctttcta ctccatcccc atagtaagag
    22441 attaatgggt ctcctggagc aagtcttgcc atgtaaaaaa caataaaaga taataaaaac
    22501 attactaaaa taaactgcaa caactttttc agtatatcct ttaacaaacc ccaacccccc
    22561 tttgttgcaa taaaaaaacc acataaaagc aaacgtaaag taacgttaaa accttcgtgg
    22621 ttccattatc attaaacaaa attaaatttt ctatatttat ctatgagtta attttagcat
    22681 catttattaa ctgtgtaaac aaacttttta aaaattgtta aaatttcatc aaattatttt
    22741 atttatacct aaaataaaat ttttatgttc tattcttcat tattttctat aaaattataa
    22801 aattttaggt tgactatata agaaaagtat attatattag tttgtatgca aaccatttaa
    22861 gaggtgattt tattgaaaag taattatgac tgttttagaa tagccatgct cttaaaagaa
    22921 ctttattcta aaactatgta cacagtagaa gaaaatttta aagaaaatgg attaacacac
    22981 caacagatta tagttataaa actggtagct cataatcaag aacttacaat atcacaacta
    23041 tgtgatgaaa tgtctttagc taaaggtacg gtttcaggca taatcagcag attagaacag
    23101 attggatata tagaaaaatt caagaaatct aatgataaaa gaaatacata cgttaagttt
    23161 acaacaacag gatttgaatt tgccacaaat tttaaaatta aaatgcaaga aagttttgat
    23221 gatattttta aaaattgtga tgaaaacgaa ttgagtgact tagtaaaaaa tcttagaaat
    23281 atattggcaa aagtaaagga gagataatta tgaattataa attaatactt gcaatagtat
    23341 ttataacatc agctttaatt ttctacacta taggtgtatt tggagaaaga aaggcaaaaa
    23401 ttttaaaaaa gaaacatgta attatatttt ggcttgggtt tatatttgat actttaggaa
    23461 catttacaat gagtaacata gccaacagcc atacttttga agtaaaatct gctttatcac
    23521 aaaaccttca tagtattaca ggtcttcttg caattgtgct tatgcttttt catgcaagtt
    23581 gggctacttt tgtcctatac aaagatgatg aggaaaagaa aaaattcttt cataagttta
    23641 gtatagttgt atggactata tggttagttc catactttat aggtatgttt attggtatgg
    23701 ttggatagta aaataaaaag tgtgtaagaa atactgtagg taaatttgta taagacaaat
    23761 ttatctacat ccttctttca cacttttaca tatttatcta taatactcca ttatttcttt
    23821 catgtttctt aatacctata tagaatattt aattgtttct atagtatttt attattttct
    23881 cacacttttt ca
//
LOCUS       DAMJYN010000055        23174 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.056, whole genome shotgun sequence.
ACCESSION   DAMJYN010000055 DAMJYN010000000
VERSION     DAMJYN010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 23174)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23174)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23174
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.056"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(178..546)
                     /locus_tag="PC466_002431"
     CDS             complement(178..546)
                     /locus_tag="PC466_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF2769800.1"
                     /translation="MKKIPKSELLVMNFIWDKGIDKIPAREVANYMEISHGWTKGTTG
                     KVLSRLSDKGFLEFEKDGRNTLYTIKVKHEEYLKFETKDFLELIHKNSIHSFISSLGC
                     GNEISDDDIKELEQWLKKRK"
     gene            complement(1074..1496)
                     /locus_tag="PC466_002432"
     CDS             complement(1074..1496)
                     /locus_tag="PC466_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HDF2769801.1"
                     /translation="MNTFKTEVLLKYSAKDIFNIFTKSARLNFPNFNEKKAVGTFVQQ
                     KNNKRFKVEITNFEKNRVYEIKTSNKRESTITRYELVHIDLENTKLIFIESESKRNIF
                     GKINSALVRVLFGKRQPEEFNKFIKKLEMELENNSVNL"
     gene            1974..4877
                     /locus_tag="PC466_002433"
     CDS             1974..4877
                     /locus_tag="PC466_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2769802.1"
                     /translation="MELRDKLVNIINTENKKDPLTDVQIAKFLSTTRENITNLRKELN
                     ISNSRQRRYPYLKSAISAILQKNKNISISEITRELMTEGFNISRRVVEELLPKESLEM
                     DVVEESEEESNDPFETLIGNKGSLRNAVEQAKSAILYPPKGLPTLIIGESGVGKSLFS
                     RHMYEFAKQKKIVKESSNFVVFNCADYSDNPQLLLSLLFGYKKGAFTGAEYDTPGLVE
                     EADEGVLFLDEIHRLPPKGQEILFSILDRGKFRRLGETNAERKVSIMLIGATTENVET
                     NLLLTFRRRIPMLITLPPLHDRLLKEKIDLIYNIFQQECNRINAKIFVDKNVIEILVL
                     KKFSGNIGQLQNMIQVLCARAFMKFINSKDEDSESIVVVDINEVLKLKDSFKDAAFQE
                     IEYTEIRKYLKNAIFIPFNLEESSVKGSLLSDEYILPEDIYKTIEKKYYDLKSLDIED
                     IDIENILWTFILNRFADLKFNLDSNEEIFSMSDLNSFVSDSLVKLVKELMNDIVEKNM
                     NLEVNKNMFKYLAIHLEEAIKRIKLNQKIINVNLEKIKIDFSKEYEISKSFAIKIEES
                     ISIKIPDDEIGFITLYIKSALKNEVKKDKVGLIIISHGRIATETVNVVKELLGVKFPV
                     AIDMPLDEKPINIYNKAVELSKIIDQGKGILFLVDIGSLTNIGQIVNKRTNISTKTID
                     RVDLLMALEATRKVSMGEEELDEIFFSLLKDRMGYNYELEKHIDKSNAIVTLCLTGEG
                     TAKYISKTLEEKYDNTKCYQMSALDENLFCKIENLKETNNILAIVGTINPKIPGINFI
                     PYNKELFKNLDIYLSKSKQQDDRPVKSYERMLDEDLVIFEPDIYFKKDLLEYVCSILI
                     NKEYVEKDYLDSVLHREEMLPTYSKGAIGVPHGDSSTVNSTRFVFVKLKNPIDWGVGN
                     VNFIFMPVFQANDKEIVKNVLEILKDAEFMNNANKCFDKDAFRRIIFDKFKHL"
     gene            4910..5356
                     /locus_tag="PC466_002434"
     CDS             4910..5356
                     /locus_tag="PC466_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2769803.1"
                     /translation="MNVDLISLGLESNDYESVIEELGSIMCKKEYVKETYINAVLERE
                     RTLPTGLDIGEMCVAIPHTDSKHVNESNVAVGILKNPVKFNSMIDPKDRLDVELVFLL
                     AVKNPDSQVKLLKDLMSVFQNIKLLKNIKNASTKEEVAKLLDFIEI"
     gene            5479..5781
                     /locus_tag="PC466_002435"
     CDS             5479..5781
                     /locus_tag="PC466_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2769804.1"
                     /translation="MKQFNVLSVCGSGTVTSSMVAGKLKEVLGNKGISITTTEARPTE
                     ALNLAQSGRFDFITFTSPLQTGDYGIPTINAFACLTGIGEEAFFEEVLTVIEGIDK"
     gene            5962..7368
                     /locus_tag="PC466_002436"
     CDS             5962..7368
                     /locus_tag="PC466_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HDF2769805.1"
                     /translation="MLEFMKSIIDTFGSAIIVPIIIFIIAKIFKVTTKKSFLSAVYAG
                     VALQGFTLILNSFTPIITPVINRMVESTGVNLPVFDVGWQATSLVAFSTSAGMIYLGL
                     GILLQTILFLIKWTDVFQPSDLWNNYSYMVWGAMVIGVTGNFPLGIACMVLLNLYSLL
                     ISELVAKRWSSYYRYPNCTIIAMHNVEASVFAVFSDPIYNKLGLNKIKLNPKELEKKL
                     GFLGEPITLGLFLGMFIGILGNMTRINTMEAWGEIMKVGISTSAVMAIFPKVASMFAQ
                     AFAPITEAARKIMQKAGNREWYIAVNDAVGYGEPATLISGLILIPIMLVISMVLPGNK
                     VLPVVDLLAIPYMVQGLVAIHNGNIPKVLVSGIIWFGLGLYVCTSTAPLFTDMATNIG
                     VAIPAGAMLITSFNILGKPLMGLVFFAFLSANPIYIGLSVVIYFVLWALFRKNKTSIL
                     DYLEKQALKNVEEEPVAV"
     gene            7712..8770
                     /locus_tag="PC466_002437"
     CDS             7712..8770
                     /locus_tag="PC466_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012101107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HDF2769806.1"
                     /translation="MGDKMRASVLYNVGDVRYEMVDIPEITDTQVLVNVKYVGICGSD
                     LPRSMVSGLSGNTKYPLILGHEFSGEVVKIGEKVKHINVGDRVAVAPLVPCGKCDYCN
                     EGNFGLCDDYNIIGTRVNGAFAEYVRVPEEHILKLPDTLDYETAAGIEPATIAYHGIS
                     KSNIRVGDSVVVLGCGPIGQFVIQWAKVFGASKIIAVDIFDEKLELSKLLGANYILNS
                     KEVNVIKEIKKITNGGADVVIETAGSRFTQEQSLFVAKKRGNIVFVGISHTELPLSAD
                     ATECILRGELTLKGSWNSYASPYPGRAWTATLDFMGKGDIIFKPMISHKIGLNEVGDF
                     LSKMSKREINFNKILVEI"
     gene            8845..9531
                     /gene="araD"
                     /locus_tag="PC466_002438"
     CDS             8845..9531
                     /gene="araD"
                     /locus_tag="PC466_002438"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HDF2769807.1"
                     /translation="MLEILKEEVLKANLELPKKKLITYTWGNVSGIDREKGLVVIKPS
                     GVEYSNMTVEDMVVVDLEGNVVDGKLRPSSDTPTHLVLYKEFEELGGIVHTHSSWATI
                     WAQIGKSIPSCGTTHADYFYGSIPCTRKMTREEICNEYEKETGNVIIEEFMGRNPIHC
                     PGIIVNDHGPFTWGKDANEAVHNAVVLEEVAKMAYYTELMSPDNIMDKVLMNKHFSRK
                     HGKNAYYGQK"
     gene            9549..10196
                     /locus_tag="PC466_002439"
     CDS             9549..10196
                     /locus_tag="PC466_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HDF2769808.1"
                     /translation="MLDSLKGKVVEIAIKAEHYGLCKEKTGNFSIRDKDTGYILITPS
                     GIGREELNVEHICVLDLNGNVIEVEKGIKPSSEVLMHIEIYKIRENINAISHTHSLYA
                     TAFSVAKKPIIPIVYESVNYGGYVDIAPYERPGTLKLAKSVSKLLIDTDACLLERHGL
                     TTVGNDLDEALLKSRYVEEVAEIYYRSLVLNQFKELEVVDVDEFESWKYPEEIKF"
     gene            complement(10369..11736)
                     /locus_tag="PC466_002440"
     CDS             complement(10369..11736)
                     /locus_tag="PC466_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HDF2769809.1"
                     /translation="MNLIDILNKVDAFIWGPPLLVLLVGTGILLTVKLGVVQITKLPR
                     ALKLIFSAENKGSGDVSSFAALCTALAATVGTGNIVGVATAIKAGGPGALFWMWIAAF
                     FGMATKYSEGVLAIKYRTKDKNGQVSGGPMYYIVNGMGEKWRPLAIFFAISGILVALL
                     GIGTFTQVNSITDAINNSFGIDPRITGVVLAVFVALVVFGGLRSISNVATKIVPFMAV
                     IYVVICGIILISFWNKIPETFMLIIKSAFTPTAATGGFLGATMSLAIRNGIARGVFSN
                     ESGLGSAPIAAAAAKTEWPAEQGLISMTGTFIDTIIICTLTGFSLVISGVWCSDLNGA
                     VMTQAAFNGAIPTFGPILLTVSLTLFAFTTILGWSYYGERCFEFLFGVKGMNGYRTVF
                     VAMVLLGAFLKLEVVWIIADIVNGLMAIPNLIALLALSPIIVSETKKYFEHINSPENQ
                     IKKNA"
     regulatory      complement(11926..12014)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            12442..14562
                     /locus_tag="PC466_002441"
     CDS             12442..14562
                     /locus_tag="PC466_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HDF2769810.1"
                     /translation="MGKILVLAEKPSVGRDIAKVLGSKNEKNGYIEGPKYVITWALGH
                     LVTLADPESYGERYKSWSLEDLPILPKHLKTVVIKKSGKQFNTVKSQMNRNDIDEIVI
                     ATDAGREGELVARWIIEKSQVKKPIKRLWISSSTDKAIKDGFAKLRSGKEYENLYYSA
                     IARAEADWIIGINATRALTTKYNAQLSCGRVQTPTLAMLLKREEEIRNFKPKEYYGLE
                     LIATKGNSDIKFIWNDKNNNSSTFSKEKIESILKKVKGVDIKISEVNKSYKKKYSPAL
                     YDLTELQRDANKMFGFSAKETLSIMQKLYEHHKVLTYPRTDSRYLTSDIVGTLKDRIK
                     AVNISDYSKICNKLLKSNIIANKSFVDNSKVTDHHAIIPTEQKVFMSDFSDKERKIYN
                     LVVKRFLAVLSPPFEYEQTTISATVEGEIFKAKGNKVINLGWKESYKDIEDEDEYESI
                     PNVLEKDVLKVKGLKITSGKTNPPPYLNEGTLLTAMEKNGLGTVATRADIIEKLFNSF
                     LMEKKNKEIYITSKGRQLLDLVPVDLKTPELTASWEKKLLDISKGKLSKNTFINDMKD
                     YSKDIVLEVKNSDNKFKHDNLTKNRCPECGKFMLEVNGKKGKMLICEDRECNTRKTIS
                     QVTNSRCPNCHKKLELRGEGEGRIFTCSCGYREKLSSFNKRKQEEKQKASKKDVNQYL
                     KNQNKNQETFNNPFAEALAKLKNK"
     gene            14666..15919
                     /locus_tag="PC466_002442"
     CDS             14666..15919
                     /locus_tag="PC466_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FliS"
                     /protein_id="HDF2769811.1"
                     /translation="MDLSGIFKYYCKECENTWNNSSVELFEDIETYSKDSQKKREKEL
                     DKFINTISVHLERYPSDAVLRKMWVKKGEVFLQKTLEKENIFKLEKMDVEDRKKFLDI
                     TKQFIRDARKFDDDLPIGDIMQAMRNVWISNALQLLFGKEIYYSKANFAYSMLYPYTD
                     NYLDNTNIDKNDKILFNNWLEKRLLGEHIKSKDYHESKVSQMIDYIESVYPREKFTQV
                     YESLLLIFKSQVNSLKQHGKENHLCKEDLLSISIEKGGSSVLVDGYLISGFMTKEEIE
                     FCIGYGFLLQISDDLQDIKEDLKYNHKTIITEMSKEGTLDKVVNKLINFTIELIDSFK
                     INNKNKSVITMIKNDCLMLILFSVVYNAEFFSVGYIKEVEKFIPYTIDYSLEIEEKIK
                     EKFKNIDVLNNENEYKEMIDIICAE"
     gene            complement(16073..17134)
                     /gene="ytvI"
                     /locus_tag="PC466_002443"
     CDS             complement(16073..17134)
                     /gene="ytvI"
                     /locus_tag="PC466_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation integral membrane protein YtvI"
                     /protein_id="HDF2769812.1"
                     /translation="MDIQKQKNFIIKFTYVVLITSIVYIVLKFLLPLLMPFVISFIIA
                     SILRPIIRLITNNTNLNRTLISIVILLIFYGLCIFLLVSFGVKIFASVSDVFFRLPEI
                     YKSSIQPTLNTLFSKIDASTPNVNLSLILGWDNISQSMMSLVASISTNALNAIASIAS
                     KTPAFMLKLIITLIASFFFTFDYQKIVNFILKQFPEKSQFMIINIKNSSINALLKLLK
                     AYAILLSVTFLELLIGLTILKVENAFTISVIIALVDILPVLGTGSILTPWMIISLING
                     NINLAIGLLILYIIITVVRQILEPKVVGHQIGLYPLITLMCMFIGAQLFGIAGLFGFP
                     IAATIIKNLHDNGIITAFK"
     gene            17408..18148
                     /locus_tag="PC466_002444"
     CDS             17408..18148
                     /locus_tag="PC466_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein phosphatase"
                     /protein_id="HDF2769813.1"
                     /translation="MKNFRDLGGNKTEDGRTVKKGLFYRSAKLSNLSENDIKILKELN
                     IKYIFDYRSDEEARKHPSTIISNIKNIRIPAMRELEESGGSFGSIEDMIDGLFEKDGA
                     FNMLNNSYYNLPINNPSYKKLVELIRDYSNLPILNHCTAGKDRTGVGSAIILMILGVS
                     RENIMKDYLKSNDFADKEIERFIEYKPKFKDIPKENLKYIFGVNEEYMKTAFRRIDEE
                     YISVEAYLYGEFNLNKEEIRKLRNQYLE"
     gene            18160..19938
                     /locus_tag="PC466_002445"
     CDS             18160..19938
                     /locus_tag="PC466_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDF2769814.1"
                     /translation="MSLNITARQINIIKILLNSKDTISGIALSQEIGCSSKTIQNEIK
                     DINKQLRNGKILSIRGVGYKLEGSFDEVNLNSNLYDDVDRVEYIIRKILTLSNEEKNT
                     IKLEDLADSMYVSVSTVKNDLKEVKRILEKYSISVKSKHKQGICVLESEDKILNCIVD
                     LSNKRDNQLSLNDFLNDDIKERKLLIKKLLLDILNENGLVLTDIEFKSVLNNILVMLS
                     RHKYNEKEFIENYIENYRSKRSSILENEQNKEIIINSIKTFCKNLKLATSIDISNDKV
                     FEEFLYKHISSLCKKIKLGINQSPIMAQDIKIKYPFAFELANIAKKTIEKDLKIEINE
                     DEVANIALHIGGAVERASYNNKDKVFKTIIVCTSGIGTSMLIKAKLENIFKEKLEILK
                     IIPSYLVEYIKVIDVDFVISTVPIEVGDVPVINISPILSEKEIRLIEKYIETGNIYLD
                     LDIKSLFDSELFFTDLVFKRKEEVIDFMASKLVQKGYIDEDMKKSYFEREKIATTEIG
                     NMVTIPHGAIGKIFDNKIAIGILKKPISWEISDVRLIIMLALDKDKILDYEVIFSKIY
                     KRVDSIAKVISICENSSFEKFVNLFN"
     gene            20105..21022
                     /gene="pfkB"
                     /locus_tag="PC466_002446"
     CDS             20105..21022
                     /gene="pfkB"
                     /locus_tag="PC466_002446"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HDF2769815.1"
                     /translation="MIYTVTLNPSIDYIVKLDELKTGSTNRVKEEYVYPGGKGINVSR
                     ILKELGNDNTSLGFISGFTGEYIIRTLEEKELKTDFIKIKSGFSRINVKIKALKETEI
                     NGQGPNIDDEDIDTLYKKLDKLNQDDILILAGSIPSTLDEKLYENIMARLEKKNIKVV
                     VDATKNLLLNVLKYKPFLIKPNNDELEELFGVKLNSIEDMVKYAKRLKEMGAINVLVS
                     MGKDGALLITEEDEVLISDVPKGKVKNSVGAGDSMVAGFISGYLNTGKYDYALKLGAA
                     SGSATAFSYDLAKREYIDKLVNEISVKQF"
     gene            21059..22978
                     /locus_tag="PC466_002447"
     CDS             21059..22978
                     /locus_tag="PC466_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2769816.1"
                     /translation="MKIIDLLDEKSIKLNLNSKTKSEAIEELVDLVANSGNLNDKENY
                     KKAILAREEMSTTGIGEGVAIPHAKNSSVTKACIAAAVSKEGIDYESFDGSLSNLFFM
                     IAAPDGANNTHLEVLSRLSTILMDEDFRNKLINSSSEKEFKEIIDKKEREKFSEEYQD
                     EKVAEKNIIDTKENDANKYPKVLAVTACPTGIAHTFMAAESLNKMAENKGVSIKVETN
                     GSAGVKNKLTKDEIENATCIIVAADKNVEMARFNGKKVIKTKVADGIHKAEELIDKAV
                     NGDAPIYHGGDGSHNESNEESESGFRKVYKHLMNGVSNMLPFVIGGGILIAIAFLLDD
                     YTINPSNFGSNTPIAAFFKGIGDKAFGFMLPVLAGYIAYSISDRPAFVVGFVGGALAG
                     DGGSGFLGALLAGFIAGYLVEGLKKIFSVLPASLEGIKPVLLYPLLGTLLMGIIMTFL
                     VIPPVTAINNAMVGFLNGLGGTSKIVLGLVLGGMMAVDMGGPVNKAAYVFGVASLESG
                     QFEIMAAVMAGGMVPPLAIALATTFFKNRFTKEERDSGKVNYVMGLSFVTEGAIPFAA
                     GDPLHVIPACVGGSAVAGALSMLFNAALRAPHGGVFVIPVVTHPFAYILAIAVGALVG
                     MMLLALLKKPLNQEV"
BASE COUNT         9230 a         2518 c         3926 g         7500 t
ORIGIN      
        1 taaatttatt ttagatataa acatcattct gactactatt aaaagacata taaaataatt
       61 aaacttaaaa gtatatttgc ttatcttttt agtaaataaa atgaaaaaaa gaattagtag
      121 acttatgtaa atattaaatt taataacttc tataaataat tccataaaat acgtctccta
      181 ttttcttttt tttagccatt gttcaagttc ttttatgtca tcatctgata tttcatttcc
      241 acaacctaat gatgatataa agctatgaat agaattttta tgtataagct ctaaaaaatc
      301 ctttgtttca aattttagat attcctcatg tttaacttta atagtgtata aagtatttct
      361 accatctttt tcaaattcta aaaaaccttt atcacttaat ctagaaagta ctttaccagt
      421 agtacctttt gtccatccat gagaaatttc catataatta gctacttctc tggctggtat
      481 tttatctatg cctttatccc atatgaaatt cataactaac aactcggatt ttggtatttt
      541 tttcaatata atcactcacc tttaacttga ttatattaga caaatgtcta atagtcaata
      601 taatatatca tcatgtataa agaatcttta tattatttta tgcttgagaa ctaagtagta
      661 tagatttata gataaaaaag atattgagag ttttatggaa gaggggaata tattttctat
      721 tagagataag aatatgacat atatttttta ttgatttgta caaaaatact atatagtgaa
      781 taaattaata tcttttctaa attagaagag gataatctta ttagataaag attatcctct
      841 ttattgaaag tttaagggat attagagatt attaattttt ctctcttttt ttaactaaaa
      901 gcaataatac ataaaattat tattgctaat gatactctta atgtggtata tagtcatagt
      961 gtcacatgtt tatcaatagt tttttcatta attattgtaa cgaatagtag gactcataaa
     1021 atacttagaa atatgttttt agatagattt taaatatata atctaactta tatctataaa
     1081 ttaacactat tattctccaa ttccatttct agttttttta taaatttatt aaattcttct
     1141 ggttgccttt ttccaaacaa tactcttaca agagctgaat tgatttttcc aaatatattc
     1201 ctcttgctct cactttcaat aaaaataagt tttgtatttt ctaagtcaat atgtactaat
     1261 tcatatctag taatagtact ttctctttta ttgcttgttt ttatctcata tactctattt
     1321 ttttcgaaat tagttatttc aaccttaaat cttttattat ttttttgttg tacaaatgtt
     1381 cctactgctt ttttctcatt aaaattagga aaatttagtc ttgcagattt tgtaaatata
     1441 ttaaatatgt cttttgcaga atattttaat aaaacttcag ttttaaatgt attcatatcg
     1501 ttttcccttc tgtatataaa tttaatattt ataagttaat ttttaagtta aaatagtata
     1561 atatgccata ttaaatcatg ttaaaactat ttatatagct aaaaccttac ctatataagt
     1621 atgtatacta tcatataaaa ataaaatctt aaaatagaaa gggttaaaaa cacagtttat
     1681 tataattttt attgttgagt agatacgtac tattatatat gattgagcaa gtttttcaat
     1741 cataaattta taaagtattt tgcattaaaa tttaaacaaa gagttaaatt atttaagatt
     1801 atgaataact aatacattta gtaaattact aaatatacaa aatgtaaata cttatcaaaa
     1861 tgtataaata cttatgacat ctagttactt acagggttta agtagaaaaa aatatcaaag
     1921 taagtatggc atgatagttg cttatatatt tatcaagaaa ggagttatta agcatggagt
     1981 tgagagataa acttgtaaac atcataaata cagaaaataa aaaagatcca ttaacagatg
     2041 ttcaaatagc aaagttttta agtacaacta gagagaacat aactaatttg agaaaagaac
     2101 ttaatataag taattcaagg caaagaagat atccttattt aaaatcagca atttcggcaa
     2161 tattacaaaa gaataagaat atttctatat cagaaattac aagggaattg atgacagaag
     2221 gctttaatat atcgagaaga gttgtggagg aacttttacc taaagaaagt ttagaaatgg
     2281 atgtagtaga ggaatctgaa gaagaatcga atgacccatt tgaaactctg ataggtaata
     2341 aagggagtct tagaaatgct gtggagcagg ctaaatctgc tatattgtat ccaccaaaag
     2401 gattaccaac gttgattatt ggggaaagtg gagttggtaa gagtttattt tctagacata
     2461 tgtatgagtt tgcaaagcaa aaaaagatag taaaagaaag ctccaatttt gttgtattta
     2521 actgtgctga ttatagtgac aatccacaat tattattatc tttgttattt ggatataaaa
     2581 aaggtgcatt tacaggtgct gaatatgata caccaggtct tgtagaagaa gctgatgaag
     2641 gagttttatt tttggatgaa atacatagat tgcctccaaa aggtcaagaa atactatttt
     2701 ctatcttaga taggggaaag tttaggagat taggtgaaac taatgctgaa agaaaagtaa
     2761 gtattatgtt gattggggca actactgaaa atgtagagac taatttatta ttaacattca
     2821 gaagaaggat accaatgcta ataactttgc caccattaca tgatagatta ctaaaagaga
     2881 aaatagacct tatatacaat atctttcaac aagagtgtaa tagaataaat gcaaaaatat
     2941 ttgtagataa aaatgtgatt gaaatacttg tactaaaaaa gtttagtgga aatataggac
     3001 aattacaaaa tatgattcag gttctttgtg caagagcttt tatgaagttt ataaattcca
     3061 aagatgaaga tagtgaatcg atagtagtag tagatataaa tgaagtttta aagcttaaag
     3121 attcttttaa agatgctgcc tttcaagaga ttgaatatac agagataaga aaatatttga
     3181 aaaatgctat atttatacca tttaatttag aagaatcatc agtaaaagga agtcttttaa
     3241 gtgatgaata tatattacca gaggacatat acaaaacaat tgaaaagaaa tattatgacc
     3301 taaaatccct agacattgaa gatatagata tagagaatat tttatggact tttattttaa
     3361 atagatttgc tgacttaaag tttaatctcg atagtaatga agaaattttt tcaatgagtg
     3421 atttaaatag ttttgtaagt gatagtttag ttaaactggt aaaagaactt atgaatgata
     3481 tagttgaaaa aaatatgaat ttagaagtaa ataaaaatat gttcaaatat ctagcaatac
     3541 acttagaaga agctataaaa agaattaagc taaatcaaaa gataataaat gtaaatttag
     3601 aaaaaataaa gattgacttt tcaaaagaat atgaaattag taaaagtttt gcaataaaaa
     3661 ttgaggaatc aattagtatt aagattccag atgatgaaat tggatttata acactctaca
     3721 taaagtctgc tctaaaaaat gaagtgaaaa aagataaagt agggttaata ataatttctc
     3781 atggacgtat agctacagag actgtaaatg tagttaaaga acttttaggt gtaaagtttc
     3841 ctgtggctat agatatgcct ttagatgaaa aaccaataaa tatatacaat aaggcagtag
     3901 aactgtcaaa aataatagac caagggaaag gtatattgtt tttggtggat attggttcac
     3961 ttacaaacat aggtcaaata gtaaataaga gaaccaatat aagcactaaa actattgata
     4021 gagtagacct cctaatggca ctagaagcaa ctagaaaagt ttctatggga gaggaagaac
     4081 ttgatgaaat atttttttct ttgctaaaag ataggatggg atataactat gaattagaaa
     4141 aacacataga taaatcaaat gcaattgtaa cattatgtct tactggagaa ggaactgcta
     4201 agtatataag taaaacgttg gaagaaaagt atgataacac taaatgttat caaatgagtg
     4261 cattggatga aaatttattt tgtaaaattg aaaatctaaa agagacaaac aatatattag
     4321 ctattgttgg gacaataaac cctaagatac caggtataaa ttttataccc tataataaag
     4381 aacttttcaa aaatttggat atctatctat caaaatcaaa acaacaagat gacagaccag
     4441 ttaaatcgta tgaaagaatg cttgatgagg atttagtgat ttttgaacca gatatatatt
     4501 ttaaaaagga tttattagaa tatgtatgtt caattcttat aaataaagaa tatgtagaaa
     4561 aagattactt agattctgtt ttacatagag aagaaatgct tccaacatat tctaaaggag
     4621 ctataggtgt gcctcatgga gattcttcta ctgtaaatag tacaaggttt gtttttgtta
     4681 aactaaagaa tcctattgat tggggtgtag gtaatgtaaa tttcatattt atgccagttt
     4741 ttcaggctaa tgataaagag attgttaaaa atgttcttga gatactaaaa gatgcagaat
     4801 ttatgaacaa tgccaataag tgttttgata aagatgcttt tagaaggatt atatttgata
     4861 aatttaaaca tctgtagcca tagcaaaaaa attgagagga gttagagtaa tgaatgtaga
     4921 tttaatatca ttgggtttag aatctaatga ttatgaaagt gttattgaag aattaggaag
     4981 tataatgtgt aaaaaagaat atgtaaaaga aacatacata aatgctgtct tggaaagaga
     5041 aaggacatta ccaacaggtc tagatattgg agaaatgtgt gttgctattc cacatacaga
     5101 ttcaaagcat gtaaatgagt ctaatgtagc tgtagggata ttgaaaaatc ctgtaaagtt
     5161 taattcaatg atagacccaa aagatagact tgatgtagaa cttgtatttt tattagcagt
     5221 aaagaaccca gattcacaag taaaactgtt aaaagattta atgtcagttt ttcaaaatat
     5281 aaagttatta aaaaatataa aaaacgcatc aacaaaagaa gaagtagcta aattattgga
     5341 ttttatagaa atttaatgta ggagaatttt ataaataaaa aattaaaatt tcaacaatca
     5401 aagtaagtat tattttttta ataggtttaa tcttatataa aataaaaatt tagagtgaaa
     5461 aattaggagg aaattattat gaaacaattt aatgtattat cagtttgtgg ttcagggaca
     5521 gttacatcat ctatggtagc aggtaaatta aaagaagtac taggtaataa ggggatttct
     5581 attactacaa cagaagctag accaacagaa gcactaaatt tagcacaatc aggaagattt
     5641 gactttataa catttacgag tccgcttcaa acaggcgatt atggaatacc aactataaat
     5701 gcatttgctt gcctaactgg tataggggaa gaggcattct ttgaagaagt tttgactgtt
     5761 attgaaggca tagataagta agttttggag acgtgaattt atagtattta aatcaatgat
     5821 ttagatacta taataagcta atattaacta aatatttgtg gaaaaaacat tttatatgtt
     5881 gtcataaatt aaaaaattat aaaaatagtc acttaagtat taaattaagc ttataaatat
     5941 ttataagtag gagggaaaaa gatgttagaa tttatgaaat ctataatcga tacatttggt
     6001 tctgcaatta tagttccaat tataatattc ataatagcaa agatatttaa agtaactact
     6061 aagaaatcgt ttctttctgc tgtgtatgca ggagttgctt tacaaggttt tacactgatt
     6121 ttaaattcat ttacaccaat aataacacca gttatcaata ggatggttga gagtacagga
     6181 gtaaacctac cagtttttga tgttggttgg caagcaacat cattggttgc attttcaaca
     6241 agtgcaggta tgatatattt aggtcttggt atattattac aaacaatttt atttttgata
     6301 aaatggacag acgtgtttca accatcagat ttatggaata actattctta tatggtatgg
     6361 ggagcaatgg ttataggagt aacaggaaat tttcctttag gtatagcatg tatggtttta
     6421 ttaaacttat atagtttatt aatatcagag ttagttgcaa agagatggtc tagttactat
     6481 agatatccta attgtacaat aatagctatg cataatgttg aggcttctgt gtttgcagta
     6541 ttttcagacc ctatatacaa taaattggga ttaaataaaa taaaattaaa tccaaaagaa
     6601 ttagagaaga aattagggtt tttaggtgaa ccaattactt taggtctttt tttaggtatg
     6661 tttataggta tattaggtaa tatgacgaga ataaatacta tggaagcttg gggagaaata
     6721 atgaaagtag gtatatctac aagtgcagtg atggcgattt tccctaaagt agcaagtatg
     6781 tttgctcaag catttgcacc tataacagaa gcagctagaa agattatgca aaaagctgga
     6841 aaccgtgagt ggtacatagc agtaaatgat gctgttggat atggtgaacc tgcaacttta
     6901 atatcaggtc ttatattaat tccaataatg cttgtaatat ctatggtact tcctggtaat
     6961 aaggtattac cagttgtgga tttgttggca attccatata tggttcaagg tttagttgcc
     7021 atacataatg gtaatatacc aaaagtatta gtttcaggta taatttggtt tggattagga
     7081 ttatatgttt gtacatctac agcaccatta tttacagata tggctacaaa tataggtgta
     7141 gctatacctg caggagcaat gttaataaca agctttaata tactaggaaa acctttgatg
     7201 ggattagttt tctttgcatt tctaagtgca aatccaattt atataggtct ttcagttgta
     7261 atttactttg ttctatgggc attgtttaga aagaacaaaa caagtattct tgattattta
     7321 gaaaaacaag cacttaaaaa tgtagaagaa gagcctgtag cagtttaagt ttataaaaat
     7381 gaaataagaa taattaaagg agtttataat tgattttata taagtatcag ataatacctg
     7441 agaaatattt aaatgaaata tagacttctt tttatttgat aatatttgta attataatgc
     7501 attgtatttt tatagttgag ttttctgtat aacctgctat ttaaaacata ctcttttata
     7561 tttatacagt aatgtggttt aattttataa aatgtaatct ctactggtaa aagactttgt
     7621 atataaggca tttgcctgaa taaaccattt atcttttgta tggcatagat attgctatat
     7681 agaagtatat agcatgaaag gagatattta tatgggagat aaaatgagag catcagtatt
     7741 gtataatgta ggtgatgtca ggtatgaaat ggtagatata ccagaaataa cagatacgca
     7801 agtgcttgta aatgtaaaat atgttgggat atgtggttca gatttgccta ggtctatggt
     7861 aagtggtttg agtggaaata caaaatatcc attgatttta ggacatgaat tttctggtga
     7921 agttgttaaa attggagaaa aagtaaagca tattaatgta ggagatagag tagctgttgc
     7981 accattagta ccttgtggaa aatgtgatta ttgtaatgaa ggtaattttg gcttgtgtga
     8041 tgattacaat ataattggaa caagagtaaa tggagcgttt gcagaatatg taagagttcc
     8101 agaagaacat attttaaaac taccagatac attggattat gaaactgctg ccggaattga
     8161 accagcaact atagcttatc atgggatttc aaagtctaat attagagtag gagatagtgt
     8221 agttgtgtta ggatgtggtc caataggtca gtttgttata caatgggcaa aggtgtttgg
     8281 tgcatctaag attatagcag ttgatatttt tgatgaaaaa ttagaacttt ctaaacttct
     8341 aggagcaaac tatatactta actcaaaaga agtaaatgta atcaaagaaa taaaaaaaat
     8401 aacaaatggt ggtgctgatg ttgtaataga gactgctggt agccgattta cacaagaaca
     8461 atctctattt gtagcaaaaa agagaggaaa tatagtgttt gtaggtatat cacacacaga
     8521 attaccactt agtgcagacg ctactgagtg tatattacgt ggagaactta ccttgaaagg
     8581 ttcttggaat tcatatgcaa gcccttatcc tggaagagca tggactgcaa cattggattt
     8641 tatgggaaaa ggtgacatta tttttaaacc catgatttca cataaaatag gtcttaatga
     8701 agtgggtgac tttttaagta aaatgagcaa gagagaaatt aatttcaata aaatcctagt
     8761 agaaatataa aaatttaata aaaaattcta aaaacaatta aattttataa ctatgacatt
     8821 aaataaaata taggaggaag aaaagtgcta gaaattttaa aagaagaagt attaaaagca
     8881 aacttagaat tacctaagaa aaagctaatt acttatactt ggggaaatgt aagtgggata
     8941 gatagagaaa aaggattagt ggtgataaaa ccaagtggtg tagagtatag taatatgact
     9001 gtagaagata tggttgtagt tgatttagag ggaaatgtag ttgatggcaa actaagaccc
     9061 tcctcagata ctccgactca tctagtttta tataaagagt ttgaagaatt ggggggaata
     9121 gtacatacac attcaagttg ggcaacaatt tgggctcaaa taggaaaatc tataccatct
     9181 tgtggtacta ctcatgcaga ttatttttat ggaagcatac catgtaccag aaaaatgact
     9241 agagaagaaa tttgcaatga atacgaaaag gaaactggaa atgtaatcat tgaagaattt
     9301 atgggaagaa atccaattca ttgtccagga ataattgtaa atgaccacgg accttttaca
     9361 tggggaaaag atgcaaatga ggctgtacac aatgcagtag ttttagaaga agtcgcaaag
     9421 atggcttatt atacagagtt aatgagtcct gataatatta tggataaggt tcttatgaat
     9481 aagcattttt caagaaaaca tggaaaaaat gcatactatg gtcaaaaatg attatctgga
     9541 ggtgaattat gctagactct ttaaaaggta aagttgtgga aatagcaatt aaagcagagc
     9601 attatggttt atgtaaagaa aagactggta attttagtat tagagataag gatactggat
     9661 atatacttat aaccccatca ggtataggaa gagaagaatt aaacgttgaa catatttgtg
     9721 tattggattt gaatggaaat gtaatagaag ttgagaaagg tattaagcca agtagtgagg
     9781 tattgatgca tattgaaata tataaaataa gggaaaatat aaatgctata tcacatactc
     9841 attctttata tgcaacagca ttttcagtag caaagaaacc aattatacca attgtatatg
     9901 aatcagttaa ttatggcggt tatgtagata ttgctccata cgaaagacca ggaactttaa
     9961 aattagctaa gagcgtttca aaattactga tagatacaga tgcatgctta ttagaaagac
    10021 atgggttgac aactgtaggt aatgatttag acgaagcatt attaaaatca agatatgttg
    10081 aagaggtagc agaaatatac tataggtctt tagtattaaa tcaatttaaa gaacttgaag
    10141 tagtagatgt tgatgagttt gaatcttgga aatacccaga agaaataaag ttttaatcta
    10201 aataattttc attgaagtgg ttaattaaaa tatatgtatt atttatatca attactatgt
    10261 tttattatat taatcaccgt attttgtaaa tatatttatt acattttttc aaaaaaatat
    10321 agaatccgaa agccatataa aattgacttg ggattctata ctttttattt atgcattttt
    10381 ctttatctga ttttctggag aatttatatg ttcaaaatat tttttagttt cagatactat
    10441 tataggtgat aatgcaagta aagctataag gttaggtatt gccataagcc catttacaat
    10501 atcagcaatt atccaaacaa cttctaactt taagaaagca cctaataaca ccatagccac
    10561 aaatacagtt ctatacccat tcatgccttt tacaccaaac agaaattcaa aacatctttc
    10621 tccataataa ctccatccca aaattgtagt aaatgcaaat aatgttaaac taactgtaag
    10681 taatattggt ccaaatgtag gaattgctcc gttaaaagct gcttgtgtca taacagctcc
    10741 atttaggtct gaacaccaca ctcctgaaat aacaagagag aatccagtaa gagtacagat
    10801 tataatagta tctataaaag tacctgtcat agatataaga ccttgttccg ctggccattc
    10861 agttttagca gcagctgcag ctattggagc actacctaga ccagactcat ttgaaaatac
    10921 accacgagca ataccatttc taattgccag tgacatagtt gctcctaaaa aaccaccagt
    10981 agcagcagta ggtgtaaatg cacttttaat tattaacata aaagtttcag ggattttatt
    11041 ccaaaaagat attaaaatga ttccacagat tacaacatat ataactgcca taaaaggtac
    11101 tattttagta gctacattag atatacttct aagtcctcca aatacaacca aagctacaaa
    11161 tactgctaat acaacccctg taattctagg gtctatcccg aaactattat ttattgcatc
    11221 tgttattgaa tttacttgag taaaagtacc gattcctaaa agtgcaacta gtataccact
    11281 tatagcgaaa aatattgcaa gaggtctcca tttttctccc ataccattta ctatgtaata
    11341 cattggccca ccagacactt gaccattttt atctttagtt ctgtatttta ttgcaagaac
    11401 accttctgaa tacttagtag ccattccaaa gaatgctgct atccacatcc aaaaaagtgc
    11461 accaggtcca ccagctttga tagctgtagc aacaccaaca atattaccag taccaactgt
    11521 agcagctaga gcagtacata aggctgcaaa acttgaaaca tcaccactac ctttgttttc
    11581 agcagagaat attaacttaa gagctcttgg cagtttagtt atttgaacaa ctccaagctt
    11641 aacagtaagt agtataccag taccaactaa tagtaccagt aggggtggtc cccaaataaa
    11701 agcatcaact ttgtttaaaa tatcaattag attcataaaa acactccctc attttttttg
    11761 ctttacataa tcaatagaat ttttaatgaa gtaattgaca ggaaataagt ataatttatt
    11821 aataatttct agtgtaataa aaaaagctaa atctaaaaaa gattcagctc tggatgtaca
    11881 ctaattagca accaaaataa aagtattagt aaatactgtt tttggtagat aatccctgtc
    11941 cttttgcctg agagattgag cataaaagcc ttgccccttc ggcgcccata atgggtctct
    12001 ccagagttcc gtaaatttta cagtcctact tttaaaagta cctgagagtg ttactccttc
    12061 ggtgtgctat atagcaactc ttctataaaa tcttaaccgg atattgattt gtcatagctt
    12121 attgtattaa taatattaat ataagttttt atgttttgtc aactaaaaaa ttaaaaaaca
    12181 aagaaaaaat ataaaaatgt aagcctattt acgaattata aacttagaaa gatgagtaat
    12241 atacgtaaaa atgaattttg taatacacat acaaatgaag tgtaaaataa gttttaaata
    12301 aaaaaataat aaaatcttaa ataattaatt agatatgatt aaattatggt aatattatag
    12361 ttacgatatt aagaaaagtt ctatttagtt agattttaag cgtaatatga gattatgtat
    12421 agagaaagga tgtattttta gatgggaaaa atattagtgc tagcagaaaa accttctgtt
    12481 ggaagagata tagcaaaagt tttagggtca aaaaatgaaa aaaatggtta tatagagggg
    12541 ccaaagtatg tgataacttg ggcactaggt catttggtta cacttgctga ccccgaaagt
    12601 tatggagaaa gatataaatc atggagctta gaagacctgc caatacttcc caagcacctt
    12661 aagactgttg taataaaaaa gagtggaaag cagtttaata cagttaaatc gcaaatgaat
    12721 agaaatgata tagatgaaat agttatagca acagatgcag gtcgtgaagg agaacttgta
    12781 gcaaggtgga taatagaaaa atcacaggta aaaaaaccta taaaacgtct ttggatttct
    12841 tcaagtacag acaaagcaat aaaagacgga tttgcaaaat taagaagtgg aaaagaatat
    12901 gaaaatttgt attactcagc aatagcacga gcagaagctg attggattat tggaataaat
    12961 gcaaccagag ctttgacaac aaagtacaat gcacagcttt cttgtggaag agtacaaact
    13021 cctactcttg caatgttgct taaaagagaa gaagaaataa gaaatttcaa acctaaagag
    13081 tattatggat tagaattaat tgctacaaag ggaaattcag atataaaatt tatttggaat
    13141 gataaaaaca ataattcttc aacttttagt aaagaaaaga tagaatccat attaaaaaaa
    13201 gtaaaaggtg tagacataaa aatatctgaa gtaaacaagt catataagaa aaaatattca
    13261 cctgcactct atgatttaac agaattacaa agagatgcaa ataaaatgtt tggattttca
    13321 gcaaaagaaa ctttatctat aatgcaaaaa ctgtatgaac atcataaagt acttacttat
    13381 cctagaactg attctagata tttaacatca gatattgttg gaacattaaa agatagaata
    13441 aaagctgtaa atattagtga ttattcaaag atttgtaata aattattaaa aagcaatatt
    13501 atagctaata aatcgtttgt tgacaattca aaggtaacag accaccatgc aataatacca
    13561 acagaacaga aggtattcat gagtgatttt agtgacaaag agcgaaaaat atataatctt
    13621 gtagtaaaaa gatttttagc agtactatct cctccttttg aatatgagca gacaactata
    13681 agtgcaactg tagaaggaga aatatttaag gctaagggaa acaaagtaat aaatttaggt
    13741 tggaaagaaa gttataaaga tattgaagat gaagatgagt atgaaagtat accaaatgtt
    13801 ttagaaaaag atgtacttaa ggtcaaggga ttaaagataa cttcaggaaa aacaaatcca
    13861 ccaccatact taaatgaggg aacattattg actgctatgg aaaagaatgg tctagggaca
    13921 gttgctacaa gagcagatat aatagaaaaa ttattcaatt catttttaat ggaaaagaaa
    13981 aataaagaga tatatataac atcaaaagga agacaattat tagatttagt tccagtagac
    14041 ttaaagacac cagaacttac agcttcatgg gaaaagaaat tattggatat ttcaaaggga
    14101 aaacttagta aaaatacatt cataaatgac atgaaagatt attcaaaaga tattgtacta
    14161 gaagtaaaaa atagtgataa taaatttaaa catgataact taactaaaaa tagatgtcca
    14221 gaatgtggta aatttatgtt agaggtaaat ggtaaaaaag gtaagatgtt gatttgtgaa
    14281 gatagagagt gtaatactag aaaaactata tcacaagtaa ccaattcaag atgtcctaac
    14341 tgtcataaaa aattagaact tcgtggagaa ggtgagggga gaatcttcac ttgtagttgc
    14401 ggatacagag aaaagttgtc ttctttcaac aagagaaagc aagaagaaaa acagaaggca
    14461 tcaaaaaaag atgttaatca atatttaaaa aatcaaaata aaaatcaaga gacatttaat
    14521 aatccatttg cagaagcatt agctaagcta aaaaacaaat aattttaaag ttattattat
    14581 acacaattat aactttaact gtatattagt tatatgtact gatataatat agtgtatagt
    14641 ttaggcatga aagtagggct gttaaatgga tttaagtggc atatttaaat actattgtaa
    14701 agagtgtgaa aatacatgga ataattcgag tgttgaatta tttgaggata tagaaacgta
    14761 tagtaaagat tcacaaaaaa agagggaaaa agaattagat aaatttataa atacaatatc
    14821 agttcattta gagaggtatc caagtgatgc tgtattgaga aaaatgtggg taaaaaaggg
    14881 cgaggttttc ttacaaaaga cattggaaaa agaaaatatt tttaagttag aaaaaatgga
    14941 tgtagaggat agaaaaaaat ttttagatat aacaaaacag tttattagag atgctagaaa
    15001 atttgatgat gatttaccta taggtgatat tatgcaagct atgaggaatg tatggatttc
    15061 aaatgcatta caattattat ttggtaaaga aatatattat tcaaaagcta actttgcata
    15121 tagtatgtta tatccatata ctgataatta tttagacaat acaaatatag ataaaaatga
    15181 taagatttta tttaataact ggttagaaaa aaggctcctg ggagaacata ttaaatctaa
    15241 ggattatcat gaaagtaaag tatctcaaat gatagattat attgaaagtg tataccctag
    15301 agaaaagttt acacaagttt atgaatcgtt attattaata tttaaaagtc aagtaaatag
    15361 tttaaaacaa catggtaagg aaaatcattt gtgtaaagaa gatttattat ccatttctat
    15421 tgaaaaagga ggttcatccg ttttagtaga tggatattta ataagtggat ttatgacaaa
    15481 ggaagaaata gagttttgta taggatatgg atttttatta caaatatctg atgatttaca
    15541 agatataaaa gaagatttaa aatacaacca taaaactatt attacagaga tgtcaaaaga
    15601 gggtacttta gataaagttg taaataaact aataaatttt actattgagt taatagatag
    15661 ttttaaaatt aataataaaa ataaatctgt aataactatg ataaagaatg attgcttaat
    15721 gttaatttta ttttctgtag tttataatgc tgaatttttt tctgtaggat atataaaaga
    15781 agtagagaaa tttattccat atacaataga ttattcatta gagattgaag aaaaaataaa
    15841 agaaaaattt aaaaatatag atgttttaaa taatgaaaat gaatataaag aaatgattga
    15901 tattatttgt gcagagtaga aaaaaaggga gtgtcttaga atagactttt tagtttatga
    15961 ggcactcttt ttgtataaaa tcaaatgtat tttcatcatt ttaacaatta aaaagagctt
    16021 atccctgttt gagaaagccc tttttaattt aaataaaaat gtcaaggtta aactatttaa
    16081 atgcagtaat aatcccatta tcatgtaagt tttttatgat tgtagctgcg atagggaatc
    16141 caaataatcc agctattcca aatagttgag ctccaataaa catacacatt aatgttatta
    16201 aaggatatag gccaatttgg tgtcctacta cctttggttc taatatttgt ctaacaacgg
    16261 ttataattat gtatagtatt aaaagtccta ttgctaaatt aatatttcca ttaatgagtg
    16321 agataatcat ccaaggtgtc aaaatacttc ctgtacccaa gactggcaaa atatcaacaa
    16381 gtgctatgat gacagatata gtaaatgcat tttcaacctt taggatagta agtccaataa
    16441 gtagttctaa gaatgtcact gatagtagta ttgcataggc ttttagtagt tttaaaagag
    16501 cattaatact gctatttttt atatttatta tcataaattg acttttttct ggaaattgtt
    16561 ttaagataaa gtttactatt ttttgatagt caaaagtaaa gaaaaaagaa gcaattaaag
    16621 taataataag ttttaacata aatgcaggtg ttttacttgc aatactagca atagcattga
    16681 gtgcatttgt tgaaatagaa gctactaaag acatcataga ttgacttata ttatcccaac
    16741 caagtattaa tgataggtta acattaggtg tactagcatc tatctttgaa aataaagtat
    16801 ttagcgttgg ttgtatactt gatttatata tttcaggaag tctaaaaaat acatcactta
    16861 cacttgcaaa tatcttcaca ccaaagctaa ctaataaaaa tatacacaac ccataaaaaa
    16921 ttaaaagtat tactatagaa ataagtgtac gatttaaatt tgtattattt gtaataagtc
    16981 ttataatagg tcttaagatg gatgcaatga taaaactgat tacaaaaggc attaataatg
    17041 gcaataagaa ttttaataca atatatacaa tacttgttat taaaactaca tatgtaaatt
    17101 taattataaa attcttttgc ttttgaatat ccataatata aaacctccaa tgtatttgat
    17161 attattctaa atatggtctt ttttacagaa aatatactac tgtatattga ttataaacta
    17221 taaagcttat gtaaagtaaa taaattatgt aaaatttagg ttaattttgt ataaagagat
    17281 acttttatat tttacaatta ataaccaaat actaaaaaat attttaaata aagaacttaa
    17341 aattgtgata aaattaattt atagatatta aaaaaagtat aatatatggt ttttaagagg
    17401 tgctaagatg aaaaatttta gagatttagg tgggaacaaa actgaggatg gcagaactgt
    17461 aaagaaggga ttattttata ggtctgcaaa attatcaaat ctaagtgaaa atgatataaa
    17521 gattttaaaa gagttaaata ttaaatatat atttgattat agaagtgatg aagaagctcg
    17581 taaacatcca tcaacaataa tatcaaatat aaaaaatata agaataccag caatgagaga
    17641 gctagaagaa tcaggaggaa gttttggttc tattgaagat atgattgatg gattgtttga
    17701 aaaagatggt gcatttaata tgttaaataa tagttactat aatttgccta taaataatcc
    17761 gtcatataaa aaattagtag aacttataag agactattct aatttaccaa tattaaatca
    17821 ttgtacagct ggtaaggata gaactggtgt ggggagtgct ataattctta tgattttagg
    17881 ggtatcgaga gagaatataa tgaaagatta tctaaaaagt aatgattttg cagataaaga
    17941 gatagaaaga tttatagaat ataagcctaa atttaaggac attccaaaag aaaatttaaa
    18001 atatatattt ggtgtaaatg aagagtatat gaaaactgca tttagaagaa ttgatgaaga
    18061 atacattagt gtagaagcat atttatatgg agaatttaat ttaaataaag aagaaataag
    18121 aaaattaaga aatcaatatc tagagtaaaa ggtgagttta tgagtttaaa tataacagca
    18181 agacagataa atataataaa aatattgtta aattcaaaag atacaattag tggtattgcc
    18241 ttaagtcaag agataggatg ttcttcaaaa actatacaaa atgaaataaa ggatattaat
    18301 aaacaactta gaaatggtaa aattttgtca ataagaggag ttggttataa actagaagga
    18361 agttttgatg aggtaaatct aaatagcaat ctctatgatg atgtagatag agtagaatat
    18421 ataatcagaa aaatattaac cttaagtaat gaagaaaaaa atactataaa acttgaagat
    18481 ttagccgatt ctatgtatgt aagtgtttca acagtaaaaa atgatttaaa agaagtaaaa
    18541 agaatattgg aaaagtattc aatatcagtt aaatctaagc ataaacaagg tatatgtgtt
    18601 ttggaaagtg aagataagat attaaattgt atagttgact taagcaataa gagagataat
    18661 caattgagtt taaatgattt tttaaatgac gatataaagg aaagaaaact attaataaaa
    18721 aaattattat tagacatatt aaatgaaaat ggattagtat taactgatat agaatttaag
    18781 agtgtgttaa ataatatatt agttatgtta agcagacata agtataatga aaaagaattt
    18841 atagagaatt atatagaaaa ttataggagc aaaagaagct caattttaga aaatgaacaa
    18901 aacaaagaaa ttataataaa ttcaataaaa acattttgta aaaatttaaa attagctaca
    18961 tcaatagata taagtaatga taaggtattt gaagagtttt tatataagca tattagtagt
    19021 ttatgtaaaa aaataaagtt aggtataaat caatcaccta taatggctca agatataaaa
    19081 ataaaatatc catttgcttt tgaactagct aatatagcta aaaagacaat agaaaaagat
    19141 ttgaagatag aaattaatga agatgaagtt gcaaacatag ctctacatat aggaggagca
    19201 gttgaaagag catcttataa taataaagat aaggttttca aaactataat agtttgtact
    19261 tcaggcatag gcacatcaat gttaataaaa gctaaattag agaatatatt taaggaaaaa
    19321 ttagaaatac taaagattat tccttcatac ttagttgaat atataaaagt tatagatgtt
    19381 gattttgtaa tatctactgt tcctattgaa gtaggagatg tgccagtaat aaatatatct
    19441 ccaattttaa gtgagaaaga aattagatta attgaaaaat atatagaaac aggaaatata
    19501 tacctagatt tagatataaa aagcctgttt gatagtgaat tattttttac tgatttggtg
    19561 tttaaaagga aagaagaagt tatagatttt atggcaagta aacttgtaca aaagggctat
    19621 atagatgagg atatgaaaaa atcttacttt gagagagaaa aaatagcaac aacagaaata
    19681 gggaatatgg taactatacc acatggagct attggaaaaa tttttgataa taaaatagca
    19741 attggtatat taaagaagcc tatttcttgg gaaatatcag atgttcgttt aataataatg
    19801 ttagcccttg ataaagataa aatattagat tatgaagtaa tattttcaaa aatatataaa
    19861 agagtagatt ctatagcaaa agttataagt atatgtgaaa atagtagttt tgaaaaattt
    19921 gtaaatttat ttaattagat gggtagtatt gtatatacac ctgtaaattt ggataatata
    19981 aaactaaata agataaaaac gataaatttc tcttttaatt aagagaaatt ttttgacttt
    20041 caaggatatt aatataaagt taagatataa acataaagca aataaataaa aaagaggtgg
    20101 caatatgatt tatacagtga cattaaatcc atcaatagat tatatagtta agctagatga
    20161 gctaaagaca ggaagtacaa atcgtgtaaa agaagaatac gtttatccag gaggaaaagg
    20221 tataaatgta tctcgcatac ttaaggaact tggaaatgat aatacatctt taggttttat
    20281 aagtggtttt actggagaat atataataag aacattggaa gaaaaagaat tgaagacaga
    20341 ttttataaag ataaaaagtg gtttttcaag aataaatgta aaaataaagg cgttaaagga
    20401 aactgagatt aatggacaag gtccaaatat agatgatgaa gacattgata ctttatataa
    20461 aaaacttgat aagctaaatc aagatgatat tttaatattg gcaggaagta taccatctac
    20521 tttagatgaa aaactatacg aaaatataat ggctagatta gaaaaaaaga atataaaagt
    20581 tgtagtagat gcaactaaaa atcttcttct taatgtttta aaatacaaac cttttctaat
    20641 taagcctaat aacgacgaat tagaagaact atttggtgtt aaattaaatt caattgaaga
    20701 catggtaaaa tatgctaaaa gattaaagga aatgggagct ataaatgtct tggtatcaat
    20761 gggaaaagat ggagcattgt tgattacaga ggaagatgaa gtgcttataa gtgatgtccc
    20821 taaaggaaaa gtaaaaaatt ctgtaggagc aggtgattca atggtagcag gatttatatc
    20881 tgggtatttg aatactggga aatatgatta tgctcttaaa ttgggagcag cttcaggtag
    20941 tgcaactgct ttttcatatg acttagccaa aagagaatac attgataaat tggtaaatga
    21001 gatatctgta aagcagtttt aaaatattaa aaaatatata gaaaggtaat taatatttat
    21061 gaaaattata gatttattag atgaaaagtc aattaagtta aatttaaatt caaaaaccaa
    21121 atcagaagca atagaagaat tagtagattt ggtcgcaaat agtggaaatt taaatgataa
    21181 agaaaactac aaaaaagcaa ttttggctcg tgaagaaatg agtacaacag gaattggaga
    21241 aggtgtagct atacctcatg ctaaaaattc ttcagttact aaagcttgta tagcagcagc
    21301 agtgtcaaaa gaaggtatag attatgaatc gtttgacgga agtttatcaa atctattttt
    21361 tatgatagct gcaccagacg gagctaacaa tactcatctt gaagtattat caagattatc
    21421 tacaatactt atggatgaag actttagaaa taaacttata aattcaagct ctgaaaaaga
    21481 atttaaggaa ataatagata aaaaggaaag agaaaaattc agtgaagaat atcaagatga
    21541 gaaagtggct gaaaaaaata taatagatac taaagagaat gatgctaata agtatcctaa
    21601 ggttttagca gtaacagcat gtccaactgg aatagcacat acatttatgg cagctgaaag
    21661 tttaaataaa atggcagaaa acaaaggtgt atcaataaaa gtagaaacta atggttcagc
    21721 aggtgttaaa aataagctta caaaagatga aatagaaaat gcaacatgta taatagtggc
    21781 agcagataaa aatgttgaga tggctagatt taatggcaaa aaagtcataa aaactaaggt
    21841 ggctgatggt atacacaaag cggaagaact tatagacaag gctgtaaatg gagatgctcc
    21901 aatttaccat ggaggagatg gaagtcacaa cgaatcaaat gaagaaagtg aaagtggatt
    21961 tagaaaagta tacaaacact taatgaatgg tgtatctaat atgttaccat ttgttattgg
    22021 tggagggata cttatagcga tagccttttt acttgatgat tatactatta acccttcaaa
    22081 ctttggttca aatacaccga tagcagcgtt ttttaaaggg ataggagata aagcttttgg
    22141 atttatgtta cctgtacttg ctggatatat agcatactct atatctgata gaccagcgtt
    22201 tgttgtagga tttgtaggag gtgctctagc aggtgatggt ggttcaggat ttttaggtgc
    22261 actacttgca ggttttatag caggttattt agtagaaggg cttaagaaaa tatttagtgt
    22321 actaccagct tcattggaag gaataaaacc agtattgtta taccctttac ttggaacact
    22381 tttgatggga attataatga catttttagt aatacctcca gttacagcaa ttaataatgc
    22441 aatggttgga tttttaaatg gtttaggcgg aacttcaaaa atagttttag gattagtatt
    22501 aggtggaatg atggctgtgg atatgggtgg acctgtaaat aaagcagcat atgtatttgg
    22561 agttgcatca cttgaatcag ggcagtttga aataatggca gcagtaatgg ctggtggtat
    22621 ggttccgcca cttgctatag ctcttgcaac tacatttttt aagaatagat ttactaaaga
    22681 ggaaagagat tctggtaaag ttaattatgt aatgggatta tcatttgtta ctgaaggagc
    22741 tatacctttt gcagctggag acccacttca tgttatacca gcttgtgttg gaggttcagc
    22801 agtggcagga gcacttagta tgttgttcaa cgcagctctt cgtgcacctc atggaggagt
    22861 atttgttata ccagtggtta cccatccatt tgcatatata ttagctatag ctgtaggtgc
    22921 tttggttgga atgatgcttt tagcattact taaaaaacca ttaaatcaag aagtatagca
    22981 attaaaggat attcaagaac ttaaaatatg atgttttata aaaattaata tattgctgaa
    23041 ttattttaaa ataaggattt tattaaaata aggattttat taaaataagg attttatgag
    23101 gctgttatat aacgatttgt aattgttatc ttgacagtct tttattttta tataagtaaa
    23161 ataagtgtgt tttg
//
LOCUS       DAMJYN010000056        23057 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.057, whole genome shotgun sequence.
ACCESSION   DAMJYN010000056 DAMJYN010000000
VERSION     DAMJYN010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 23057)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23057)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23057
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.057"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(94..660)
                     /locus_tag="PC466_002448"
     CDS             complement(94..660)
                     /locus_tag="PC466_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HDF2769817.1"
                     /translation="MDTKKVTFSSICIVINIVLGMVISMINIPLLFLDTVGTVLGAVV
                     LGPFWGALIGGCTNLVLGVISGPTNIPFALVNIVLGLIVGYISKKKGFGYKEAIITGV
                     ILSIVCPLIGTPISVLLFGGLSGSGADLLVGFLVQSGQKIFTAAFFPRILSNIVDKPL
                     SCIMVVYFISKMPKGFIKQYSKNTSSSY"
     gene            826..1347
                     /locus_tag="PC466_002449"
     CDS             826..1347
                     /locus_tag="PC466_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HDF2769818.1"
                     /translation="MKRNREIVVVCHCILNCNSKVEGLSEFKGAQNIAINLINKGYGI
                     IQLPCPEMIMYGINRWGHVKEQFDNLFFREQCRQMLIPHVRQFNEYLKNDYDIKSIIA
                     IDGSPSCGYNKTCSSKRWFGELSGCNELMDKINDIQMVDGKGIFIEELEKLLKEYNLE
                     IPIVGFDELREDK"
     gene            2138..4216
                     /locus_tag="PC466_002450"
     CDS             2138..4216
                     /locus_tag="PC466_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HDF2769819.1"
                     /translation="MIKISEDYIEKRFDNELLRIEAWGKNSLRIRSFVDQNFVDENYA
                     LNEKPKLNKDDITINKNEDGSAIIKNGKIKAVLDHRDRITFYNDKNEILLKEYIRLRA
                     VKHDDGGEDVGTIEITKDFNSTLKLKSREYRPSYSGEFEVTTRFESEPSEKIFGMGQY
                     QHKFLDLKNTVLELAQRNSQISVPFYISSLGYGLLWNNPGIGKVSFAKNMTEWKMFST
                     NFIDYWITCGESPKELNKNYSQVTGTVPMMPENLLGLWQSKLRYRTSEEVLDVVKEYS
                     KRGIKLSSIAIDYFHWPKQGEYKFDLDYWKNPKELVKKLKEEYSVEPIVSVWPTVQSD
                     AENYNDYLENGYLVNVNRGVRMTMQIQGNTVFVDMTNENAREYVWDRIDKNYKQLGID
                     YYWLDVAEPGYSVYDFDNYRYKKGNVLSCGNIYPIDYLKMIYDGLHNDIESVVTLVRG
                     AWAGAQKYGALVWSGDIDSSFEAFNNQVNTGLNMGLAGIPWWTTDIGGFHGGNPKDPE
                     FRELMVRWFQYATFSPILRMHGDRLPHSKPLSNKGGGSMVTGAPNEIWSYGEEVEVIL
                     TKFIKIRESLKTYLKKLMKEAHEDGTPVMRTLFYEFPEDDKTWEVDNTYMLGDEILVA
                     PIMNYKDRSRKVYLPKGHTWENIFSGVSYEGGKTYEVECPLEEIPIFLKQDSSYNFKE
                     LKNILGEVKS"
     gene            4216..4995
                     /locus_tag="PC466_002451"
     CDS             4216..4995
                     /locus_tag="PC466_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF2769820.1"
                     /translation="MEPQLWQLLLIVLYGFFINYEKNSTMFGTYQPVTAGFITGLILG
                     DINTGLYIGGTLQLLSLGISNFGGASIPDYQTASIVATFITITTKQEASVGISIGIPV
                     ALLMVQLDVLRNTIGIWLVHKAEDGAKKGNYKNITYMQMLGVLLTAATTGIPVALSVI
                     FGPSLINTILKYTPEWLTGGLTVAGGLLPAVGIGLLLRYLPAKEYFSYLVIGFVLAVY
                     MKVPLLGVALIGGAIALIIYKKNLENQEQQYTVVGGMDEDE"
     gene            4988..5797
                     /locus_tag="PC466_002452"
     CDS             4988..5797
                     /locus_tag="PC466_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HDF2769821.1"
                     /translation="MSDKVSLNKSNEKVKKSVLWRWFFTSSVSSNYEKMQALAYCYAV
                     LPFLKVVYKDNPEKLQSAVLNHLQFFNTNPWVAPYILGINVAMEELSSEETEEAVASI
                     KTGLMGPVAGLGDSLFVVIPWTIFGAIAANMAIDGSPFGILLWIVVSVALKLLSIPLF
                     NAGYTSGTKLISSIEKSLKILTESTSILGLMVVGALIPSVVKANVALNFQQGDFTMKG
                     QEILDQIMPGLVPAILVVIVYWALKKNIKPIYLILGVMVVSIILYALGILK"
     gene            5817..6299
                     /locus_tag="PC466_002453"
     CDS             5817..6299
                     /locus_tag="PC466_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2769822.1"
                     /translation="MEMKGIKNIRIDDRLIHGQVATMWSNKLGVTRLMVVNDAVANNS
                     VQKQVLRMATPAGIASSIITEETAIKNITAGKYEGQNVLLIVKSPVDLIPFVEAGFKI
                     HNINVGNMSSRKDTTVLRPNISVTEEEKEAFKRLLDEGIEITTIMTPDDKKTYLVDIL
                     "
     gene            6320..6724
                     /locus_tag="PC466_002454"
     CDS             6320..6724
                     /locus_tag="PC466_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2769823.1"
                     /translation="MNSIILMSHGNMAEEVLNSAKMIIGDSIDYPTVNMKQDDGIEGT
                     IEKLKKALEVYKESSEIIIMADLLGGTPCNAALLVANDDSRIKIISGLNLGMVIESAF
                     LDTKELAAKLEKIGKDNISMVEQNASLLSDDE"
     gene            complement(6880..8040)
                     /locus_tag="PC466_002455"
     CDS             complement(6880..8040)
                     /locus_tag="PC466_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HDF2769824.1"
                     /translation="MVTDKYTIREMNERLVLEQIIKNGPISRASIASTIGLNKATISA
                     ITKKLIDESLVHEIGIGNSTHSGGRKPILLVFNKCAGISLSMDIGYDYIFSSLSYLDG
                     TIINSKKLTDIQVSKDNVIQLIDEIINSYNISKIDTPYKVIGLTLAIHGITCENKVLF
                     TPYYNLNEIDLYSILSKKYDFPIHIENEANLTALAENTFSTVHNSLLSLSIHSGFGSG
                     IIINNKLYSGRNGMSGEIGHTIIMPNGKLCPCGNRGCLEQYCSEKKVFEQLSSLENIP
                     KIDSDIVKQLYYEDNQNAKKVIHEFCSYLTIAINNAITTYAPEIIYLNSQIISDIPEI
                     LQITKDMLVSSFNKGINIEISSLGSEASLYGGSAVNIKSFLNIQNLTLINEI"
     gene            8248..9798
                     /gene="xylB"
                     /locus_tag="PC466_002456"
     CDS             8248..9798
                     /gene="xylB"
                     /locus_tag="PC466_002456"
                     /EC_number="2.7.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylulokinase"
                     /protein_id="HDF2769825.1"
                     /translation="MKLEYVLGVDIGTSGTKTVLFDKLGNIIKSCTYEYTLIQEKSGW
                     AEQDANDWWKAVVESIREVVQSSNISSECIKGIGLSGQMHGLVMLDNEGKTLRNSIIW
                     CDQRTVKECEEITDLVGEERLIEITANPALTGFTASKILWVRNNEPDIYINTNKILLP
                     KDYIRYKLTGEYATEVSDASGMQLLDIRKRDWSDEVLEKLNIDKNLLGKVYESQEITG
                     YVTRDVASLTGLKEGTIVVGGAGDQAAGAIGNGIVKDGVVSSTIGTSGVVFAYTKEPK
                     IDKEGRVHTFCHAIPNTWHVMGVTQGAGLSLKWFKDNFCQSEVEVSNSLGEDVYEIIN
                     NQVSQVPTGCNGLLYLPYMMGERTPHLDPYARGVFFGLSPIHSKKEIARSIMEGVSYS
                     LKDCMDIIENLNIDVNEVRASGGGGKSKVWRQMQADMFNQDVYTINSSEGPALGVAIL
                     ALVGAGIYENIQKACDAIIKTSTKLEPISENVDTYKIYHRLYKRIYKSLKDDFKLLDE
                     VVNTKINN"
     gene            9894..11231
                     /gene="xylA"
                     /locus_tag="PC466_002457"
     CDS             9894..11231
                     /gene="xylA"
                     /locus_tag="PC466_002457"
                     /EC_number="5.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylose isomerase"
                     /protein_id="HDF2769826.1"
                     /translation="MSEIFKGIGQIKFEGVKSDNELAFRYYNPEQVVGNKTMKEHLRF
                     AMSYWHTLCGEGNDPFGVGTVERPWNNVTDPIEIAKIKVDAGFEFMSKMGIEYFCFHD
                     RDIAPEGRDLEETNKILDEIVEYIKVNMEKTGIKLLWGTANMFGNPRFVHGASTTCNA
                     DVYAYAAAQVKKAMEITKYLGGENFVFWGGREGYETLLNTNTELEMDNFARFLQMAVD
                     YAKEIGFTGQFLIEPKPKEPTKHQYDFDTATVLGFLRKYNLDKYFKMNIEANHATLAG
                     HTFQHELNIARINNVLGSIDANQGDLLLGWDTDQFPTNIYDATLAMYEVLKQGGIAPG
                     GFNFDSKVRRASFEVEDLFLAYIAGMDTFAKGLLIAHKLLEDEVFENFTKERYASFSE
                     GIGKDIVEGKVGFKELESYALQMPVIKNKSGRQEMLEAILNRYIYEVDTISNK"
     gene            11753..12952
                     /locus_tag="PC466_002458"
     CDS             11753..12952
                     /locus_tag="PC466_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S41"
                     /protein_id="HDF2769827.1"
                     /translation="MKKKVLFLVIILAFIILLGNSTYSQKNQLSEEEKVDDFNYVYNV
                     VKTGYPYLGVNKRLNNIDWLANKDEYTKRIKNTENDEEFIEELSSILSDLNNKHTEVI
                     DNKKRYELFKKSYSNNDWYDFLNDKKVVDRYDSMNLKIKMPDDIFVKKELILKDVIKG
                     QIGYMYLPSMSSKNGSINNDLKIIGDYINTLEKHKALIIDIRGNLGGSDRYWQGIVSK
                     LIKNDVKINGYRIYRNNNEIVKKYTNARNIKLNPVENLPASVKENAPKEIIKDFNDFE
                     DTSYTIKSTDDSKFKGNIYLLVDRKIYSSSESFAMFCKETKFATLVGETTGGDGGCID
                     PVLFNLKNSGLIVRMASCMYLNKNGICDEEFKTIPEFKVKDCKRTADFKDDNCIRKAL
                     ELENINY"
     gene            13119..13904
                     /locus_tag="PC466_002459"
     CDS             13119..13904
                     /locus_tag="PC466_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDF2769828.1"
                     /translation="MRLEEMIFLNYNKLNDTDLLIWKYITANKKHCSKMSINELAMKC
                     NVSRATITRFVKKLDLKGFSEFKVLLSWESEKVHVIENQSFDIACNSIIKYVEDQKNK
                     DYDALCKLLYESRTIYAYGSGDIQNVVAKQIKRMFLSCQEIIYDFEGRTFDDSFYNIV
                     SKNDVMIIISLSGENENTLNIARRLKLIGTKIISITEFKNNTLTDLSDESIYISATNI
                     SFLQMHPSYKLTMLYFILIELLFIKYSIYKRHRMITEGIDCKL"
     gene            14073..15638
                     /locus_tag="PC466_002460"
     CDS             14073..15638
                     /locus_tag="PC466_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003233606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDF2769829.1"
                     /translation="MMKKIQRFGGAMFTPTLLFAFAGIMVGFSIVFQNQSIMGSLATP
                     ENIWYQFWGVISSGAWMVFNQLPLLFAISLPIALAKKQQARACMEALATYLTFNYFVG
                     SMLSFWGKSFGVDFAAEISAGSGLVSIAGIKTLDTGMVGALLISGIVIYIHNRFYDKE
                     LPDFIGLFRGSSLVVAICFFVMIPVALLTCFIWPHIQNVIRHLQTFFINSGNIGVWCY
                     AFLQKILIPTGLHHFVYAPICYDSVVVPGGTSVYWATHIQDFQTSAKTLKEMYPIGFS
                     LSGLSKVFGSLGVFGAFYVTAKPEKKKKVLGLMIPATLTAVLTGITEPLEFTFLFVAP
                     LLFLVHAFLDACLQTISFALGVVGDFGGGIINWVVLNWLPLGMYHWKVYVVQVVVGII
                     FSFIWFFLFTFLIKKFDMKTPGREEDNEETKLYTKNEYLETKDEKGNKLSKASQQASE
                     YIKLVGGAENVVDVTNCATRLRLTLKDDSIISKEEDFKVVGAHGLVHNGKAIQIIIGL
                     SVPSVREEFENLL"
     gene            15652..16983
                     /locus_tag="PC466_002461"
     CDS             15652..16983
                     /locus_tag="PC466_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HDF2769830.1"
                     /translation="MERKRQRILIAGGGSTYTAGIVTMLIESVAKFPIESIKLYDNND
                     ERQRKVAEACAIIVREKNPEIKFSYTTNPEEAFTDIDFVMAQIRVGLYALREQDEKIP
                     LKYGVVGQETCGAGGIAYGLRTIGPIIEMIDYMEKYSPNAWMLNYSNPAAIVAEACRV
                     LRPNSRIINICDMPVCLEEIFARILGLNSRKDFDVRYYGLNHFGWWTSIKDKEGNDLM
                     PKLQEYCAKKGYEEFTPQGQHKESSWLETMRAAKDLLEIEPTTLPNTYLKYYLMADET
                     VEHANPNYTRANEIMDRREKDTFEECERIIKNGTARDTWFDASEHSQFIVELACALAF
                     NTQERFLLIVPNNGAIENFADDAMIEIPCLVGKDMVEPMSIGKIPTFQKGLMEQQVAS
                     EKLAVEAWIEKSYQKLWQSFTMSKTVPSAKVAKEILDEMIVANKDFWPTFK"
     gene            16997..17485
                     /locus_tag="PC466_002462"
     CDS             16997..17485
                     /locus_tag="PC466_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769831.1"
                     /translation="MITNKIKNITAVLKDENIFLSVVMVCFLILPVLYIVYLELTSLF
                     TNISFSQLLNNDVNASLNLISNFSAVYSAYVIYNIKKNKEIKENMIAFYLVLLGQIFQ
                     IYTITIVIMFTYIYKFVGIKQIISSIKELQWGKSYKALFSSIAVCLISLFVMIIRIKL
                     IM"
     gene            17499..17966
                     /locus_tag="PC466_002463"
     CDS             17499..17966
                     /locus_tag="PC466_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF2769832.1"
                     /translation="MFFKRKKEASTINSYIDGKIINLGEIPDKVFSTKVMGDGFAMIA
                     KDNILKSPTKGVISFIAQTNHAIGIKLQNDVQILIHIGLDSATTKKENFKLEVKQGQE
                     VNMGEKLVEIDNKLLENTLYIPLVIVENPNTVKYHLSNLNQEGNSGIKVINFD"
     gene            17969..19123
                     /locus_tag="PC466_002464"
     CDS             17969..19123
                     /locus_tag="PC466_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2769833.1"
                     /translation="MINKAIKFKFIIFYFFSYIIFAFASTKFTPFLSKLGYSAFERGI
                     ILSSYAITNILFQLLFGVLADKYQTMKKIVLISLSVYGIASVIMFSTESATFIIYLLL
                     VALSGGLLNTCCSLYDTWIIGCGDNINNYLSFIKTFGSIGWAIGSMVASYLILRFSYF
                     GLSVAIGLIVVLLIINILLLPDIEKINKKINVTNKDIIELLKDKKYILLVCILFLLYS
                     MVVANNCTVIDKMIALNATNSQISLKWSLQSLLEIPTYLAGSYLLKKYSSLNLLKLSA
                     IMITVQFLLFALTNDSNIIIILCVFQVFSTPLILITSKRLIFEVSPKKLRSSSQLIAL
                     SIFMGGSSLIIPTVAGFLSINIGYNYTLMILSLFGCLAYGLIVLLNYLQE"
     gene            19441..20193
                     /locus_tag="PC466_002465"
     CDS             19441..20193
                     /locus_tag="PC466_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2769834.1"
                     /translation="MKEILKIKNISKDYGIKGFKTNVLKNISLTVNEGDFIAIMGPSG
                     AGKTTLLNLMSTLDKQTSGEIILDGINISKVKNNELSKLRREKIGFIFQDYNLLDNMK
                     LMDNIALPLALGKKKSKEIEAKVFSIAKKFGLENHLDKYPYQLSGGQKQRGAAARSLI
                     TNPAVIFADEPTGALDSKSAYELLESLEKINRENNATIIMITHDPLTASYSNEVYMIN
                     DGNIKCKLNKGNSRKEFYGKIMDMLASMGGEM"
     gene            20194..22101
                     /locus_tag="PC466_002466"
     CDS             20194..22101
                     /locus_tag="PC466_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HDF2769835.1"
                     /translation="MSILGIAYNNFKSNIRTYLAFFISMVFSVVVLTNFELLRYGDAI
                     NVLQEENKKFTLSVLVAVIMILSVFLFFFIWYATNIFFKNRSKEIGILSFMGLDLYTI
                     GKIYFVENMLIGISSCITGIIIGIITSRFFQVVIIKLSGFNIKVSNGLSIEAILYATL
                     IFISIFIIMAVKGFITICRSSVINLINISKKQEKIPKVGIGIYILAIVSLIVIGYGYY
                     LSTNIRTGDITSVLPVIGIIIVGTYGLFKSVMPVIFDIIIKNKKILFNGNNIIAINNI
                     NYRLNKNYKTYAIIAIIITTTISTLGASVAMKHIHKNAQEQRNVYTISIVSMDKDEVN
                     KKQIENIIKDTNKIKYSVNPELTILKKTDIKEAYDTTDTIMKYSDFCNTLKVNGNDKE
                     LKEYGERLVSGNNVIELKSPQTIASIATKEVKTKLDGQLYNISRGEVKVPVLGTGLNQ
                     SIIVVNDDTYFKLRDKGQQVYFYGAKVFQEENSQVMFNNIEKNLSLKNGYIQNGYKAQ
                     GESQWMKFAYVVLVFLFLVFAIVAGSIIYMKIYSDAYEDKEKYKILLKIGTTEKDINR
                     AILKEVAIFYTLPMLSATISSYFALRLAGDLLMNDLSGIYILSLVICLIIFVIYGAVS
                     VNKFKSVVYKN"
     gene            22253..22927
                     /locus_tag="PC466_002467"
     CDS             22253..22927
                     /locus_tag="PC466_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2769836.1"
                     /translation="MYRILLVEDDIDLSKEIALALEKWGFKVELIDDFEVVLDEFMDK
                     KPDVVLLDVNLPLYNGFYWCEKIRAISNVPLIFLSSRDSDMDLIMGINNGADDYITKP
                     FSIDILVTKINGIIRRVYNYSDSNSILYCEDLMFDVGKGIIKHKYKDKSIELTKNEIK
                     ILTLLLKNKNRVVSRESLMMTLWDNDEFVTDNALTVNMNRLRSKVKELGFDDFIKTKK
                     GIGYII"
BASE COUNT         8914 a         2458 c         4014 g         7671 t
ORIGIN      
        1 atactatcta attaaattat taataaaaat gttatataaa aatgagtata tagcatttta
       61 aagagtaata aatcttacat aataaatgat ttattaatat gaactagaag tatttttact
      121 atattgtttt ataaaacctt taggcatttt acttataaaa tataccacca taatacaaga
      181 caaaggtttg tctactatat tactaagaat ccttggaaag aacgcagcag taaatatctt
      241 ctgaccagac tgaactaaaa aaccaaccaa taaatcagca ccacttccac ttaaaccacc
      301 aaacaataaa actgaaatag gagtaccaat taaaggacaa acaatagata aaattactcc
      361 tgtaataata gcttctttat aaccaaaacc ttttttctta gaaatatatc caacaataag
      421 accaagaaca atatttacaa gagcaaaagg tatatttgta ggacctgata taacacctaa
      481 aactaagttt gtacacccac caataagagc accccaaaaa ggacctaata cgacagcccc
      541 aagtacagta ccaactgtat ctaaaaataa taatggtata tttatcatag atataaccat
      601 acctaagaca atattaataa ctatgcatat tgaagaaaat gtgacttttt tagtatccaa
      661 ttataatacc tcctaaaaaa atatatacat ttatcatagt atagattata aaagattact
      721 aattgtatat ttctatatag aatattggaa atatagaaca aataaataat ataattatca
      781 aaatatgtag tatcattaaa attaagaata actaaggaga ttattatgaa gagaaataga
      841 gagattgtag tagtatgtca ttgtatatta aattgtaatt ctaaagtaga gggattgtca
      901 gaatttaagg gagcacaaaa tatagcgata aatttaataa ataaagggta tggaataatt
      961 caactaccat gcccagaaat gattatgtat ggaataaata ggtggggaca tgtaaaagaa
     1021 cagtttgaca atttgttttt tagagaacaa tgtaggcaaa tgttaatacc tcatgtaagg
     1081 cagtttaatg aatatttaaa aaatgattat gatataaaaa gtatcattgc aatagatggt
     1141 agtccaagtt gtggttataa taagacatgt agttctaaac gttggtttgg tgagctaagt
     1201 ggttgcaatg aattgatgga taaaataaat gatatacaaa tggtggatgg gaaaggtatt
     1261 tttatagaag agctagaaaa gctacttaaa gaatataatt tagagatacc tatagttgga
     1321 tttgacgagc ttagagaaga taagtaaaga tataaatatt tattgtctca ttatgaaaca
     1381 ccattatatt tggcagaaaa atatgactga tggacagtac ctgaatcatt tttaagtgga
     1441 gtaattagta cttataaaga tgtatctact agctgaaaga aaatgtagag aggtaataaa
     1501 tgaattgata atatatataa aggagtgtct aaaagtgaac tttttagttt atgagacact
     1561 ctttttttat attaaatcaa gtatattaaa tcaaatatat tttaatcatt ttagcaatga
     1621 aaaataaatt tatctatatt ttgagacaac atctttttta gttttattta tttgttgtcg
     1681 tttttgactt ggtatacaat tatatatttt cttaaataat ttcataaatt atttataatt
     1741 ataaaatcca ttgttttgaa caatatctaa tatattatta tctgtattta taaggtcact
     1801 atacatattt tcaagtccaa tattatctac ataataggca aattttattc ctgtatgtgt
     1861 ttaaaaaaaa ctagatgtat ataggtatca tcacagatat taaaagtata aataaaagat
     1921 attaagaacg actttcaagc aacatattag aaaattttac taaaatccgg aaagcgattg
     1981 acaaacaaag tcaaataaag tatattattg gtaagttagt ttaatgtaca aatgaattat
     2041 atataaaacc taatttataa ataacgatac taaacgacat tatttaactt aagctacaca
     2101 aagatagaat attataccat tgatttagga ggtagccgtg ataaaaatat ctgaagacta
     2161 tattgaaaaa agatttgaca atgaactatt gcgaatagaa gcatggggaa aaaactcttt
     2221 acgtattagg tcgtttgtag accaaaattt tgttgatgaa aactatgctc ttaacgaaaa
     2281 acctaagtta aataaagatg atattacaat taataaaaat gaagatggaa gtgcaatcat
     2341 taaaaatgga aagataaaag ctgtcttaga ccatagagat agaattactt tttataatga
     2401 taaaaatgaa atattattga aagaatatat tcgattaaga gctgtaaaac atgatgatgg
     2461 tggagaagat gtagggacaa ttgagattac caaagacttt aactctactc taaagttaaa
     2521 atcaagagaa tatcgaccaa gctatagtgg agaatttgaa gtaactacta gatttgaatc
     2581 tgagccttct gaaaagattt ttggaatggg acaatatcaa cataaatttt tagatttaaa
     2641 gaatactgtt ttggagttag cccaaagaaa ttctcaaata tcagttcctt tttatatttc
     2701 tagtctaggt tatggacttt tatggaataa tccgggaatt ggaaaagtat cttttgctaa
     2761 aaatatgaca gaatggaaga tgttttctac aaattttata gattattgga ttacttgtgg
     2821 agaaagccca aaagagttaa ataaaaatta ttctcaagtt actggaactg ttcctatgat
     2881 gcctgaaaac cttttaggac tatggcaaag taaactaaga tatagaactt cagaagaagt
     2941 tttagatgtt gtgaaggaat attctaaaag aggaattaag ctttcatcaa ttgcaattga
     3001 ctattttcat tggcctaagc aaggtgaata taaatttgac ttagattatt ggaaaaatcc
     3061 taaagaatta gttaaaaaat tgaaagaaga gtattcagta gaaccaatag tatctgtatg
     3121 gcctacagtt caaagtgatg cagaaaacta caatgattat ttagaaaatg gctatttagt
     3181 caatgttaat cgtggtgtta gaatgacaat gcaaattcaa ggaaatacag tctttgtaga
     3241 tatgacaaat gaaaatgcaa gagaatatgt ttgggataga atagataaaa attataaaca
     3301 acttgggatt gactattatt ggttagatgt agctgaacct ggctattctg tgtatgattt
     3361 tgataactat agatataaaa aaggaaatgt tttaagttgt ggtaatattt atcctattga
     3421 ttatttaaaa atgatttatg atggtttaca taatgacata gagtctgttg taactcttgt
     3481 aagaggagct tgggcaggag ctcaaaagta tggagcttta gtatggtctg gtgacattga
     3541 ttctagtttt gaggctttta ataatcaagt aaatacaggg ttaaatatgg gactggcagg
     3601 tataccatgg tggactactg atattggagg tttccatgga ggaaatccta aagacccaga
     3661 atttagagaa cttatggtaa gatggttcca atatgctact ttttcaccaa ttttgagaat
     3721 gcatggagat agattgcctc atagtaaacc attatcaaat aaaggtggag gctcaatggt
     3781 aactggagct cctaatgaaa tatggtctta tggtgaagaa gttgaagtaa ttcttacaaa
     3841 attcataaaa attagagaga gcttaaaaac ttatttaaaa aaactgatga aagaagcgca
     3901 tgaagatgga acaccagtta tgagaacttt attttatgaa tttcctgaag atgataaaac
     3961 ttgggaggtg gataatacat atatgcttgg agatgaaatt ttggtagctc caataatgaa
     4021 ttataaagat agaagtagaa aagtatattt accaaaagga catacatggg aaaatatatt
     4081 tagtggagtt agttatgaag gtgggaaaac ttatgaagtt gaatgcccgc tggaagaaat
     4141 tcctattttc ctaaagcaag attccagtta taattttaaa gaactaaaaa atattttggg
     4201 agaggtgaaa tcataatgga gccacaatta tggcaattat tattaatcgt actatatgga
     4261 ttttttataa actatgaaaa aaattcaaca atgtttggaa catatcaacc agtaacagca
     4321 ggttttatta ctggtcttat cttaggagat ataaatacag ggttatatat tggaggtaca
     4381 ttacagctat tatcattagg tattagtaac tttggtggag catcaatacc tgattatcaa
     4441 acagcaagta tagtagccac atttataact attacgacta agcaagaagc atctgtagga
     4501 atctctatag gtattccagt tgctttattg atggtacaat tagatgttct tagaaatact
     4561 attggtatat ggctagttca taaagcagaa gatggagcta aaaaaggaaa ttataaaaat
     4621 ataacctata tgcaaatgtt aggagtacta ttaacagcag ctacaacagg tattccagtt
     4681 gctctatctg taatatttgg accttcttta attaatacca ttttgaaata tacacctgaa
     4741 tggttaacag gtggtttaac agtagctgga ggactacttc cagcagtagg gataggatta
     4801 ttacttagat atcttcctgc taaggagtat tttagttact tagtaattgg ttttgtttta
     4861 gcagtatata tgaaagtacc attattaggt gtagctttaa ttggtggagc aattgcactt
     4921 ataatttaca aaaagaattt ggaaaatcaa gaacaacaat atactgtagt aggaggtatg
     4981 gacgaagatg agtgataagg tatcattaaa taaatcaaat gaaaaggtga aaaaaagtgt
     5041 cttatggcgc tggtttttta ctagttctgt ttcttcaaat tatgagaaga tgcaggcctt
     5101 ggcatactgt tatgcagtac tacctttttt aaaagtagta tacaaagata atccagaaaa
     5161 gttacaaagt gctgtattaa atcatttaca attttttaac actaatcctt gggttgcccc
     5221 ttatattttg ggtattaatg tagcaatgga ggagttatca agtgaagaga ctgaagaggc
     5281 tgttgcttca attaaaacag gcttgatggg accagtagca ggtttaggag atagtttatt
     5341 tgtcgttatt ccgtggacaa tttttggagc tatagcagct aatatggcga tagatggaag
     5401 tccatttgga atcttactgt ggattgtagt gagtgtagca ttgaaattat taagtatacc
     5461 actatttaat gctggctata catcaggtac taagctaata tcttcaattg aaaaaagttt
     5521 aaagatttta actgagagta catctatttt aggtttaatg gttgtaggtg cattaatacc
     5581 ttcagttgta aaagctaatg ttgctttgaa ctttcaacaa ggtgatttta caatgaaagg
     5641 tcaagaaata ttagaccaaa ttatgcctgg gttagttcct gcaattttag ttgtgattgt
     5701 ttattgggct cttaaaaaga atataaaacc tatatactta attttaggag taatggttgt
     5761 ttcaataatt ttatatgcat taggtatttt aaaataagga aaggatgata ttagatatgg
     5821 aaatgaaagg tattaaaaat attcgtatag atgaccgttt aatccatggt caagttgcaa
     5881 ctatgtggag taataaattg ggtgttacaa gattaatggt agtaaatgat gcagtagcta
     5941 acaattctgt tcaaaaacaa gttttaagaa tggctacacc tgcaggtata gcgtcatcta
     6001 taattacaga agagactgct ataaaaaata ttactgcagg aaagtatgaa ggacaaaatg
     6061 tattattaat tgttaagtct cctgtggacc ttattccatt tgtagaggca ggatttaaaa
     6121 tacataatat aaatgtagga aatatgtcaa gtagaaaaga tacaacagtt ctaagaccta
     6181 atatcagtgt tactgaagaa gagaaagaag catttaaaag acttttagat gaaggaattg
     6241 aaattacaac tataatgacg cctgatgata agaaaactta tcttgtagac atcttataga
     6301 tttaaagagg tgtattaaag tgaatagtat tattttgatg agtcatggca atatggctga
     6361 agaagtctta aattctgcaa aaatgataat aggggattct atagattatc ctactgtaaa
     6421 tatgaaacaa gatgatggaa tagaaggaac aatagaaaaa ttaaaaaaag ctttagaagt
     6481 gtacaaggaa agttcagaaa taattataat ggcagattta ctaggtggaa ctccatgcaa
     6541 tgctgcttta ttagtagcca atgatgacag tcgaattaaa attatttcag ggctaaattt
     6601 aggtatggtt attgaatcag cttttttaga tacaaaggaa ttggcagcaa aattagagaa
     6661 aataggtaaa gataatattt ctatggttga acaaaatgca agtttattat ctgatgatga
     6721 gtaggaagat tatattaata tttaaaacaa aatacttgtg ttaatactta attgatatac
     6781 aatttttaaa aaatatagct aatcttgcat aaactatata ataaatctaa ttttagaatg
     6841 tataatttaa agggttatgg ctgtatatag tcataaccct tatatttcat taattaaagt
     6901 taaattttgt atattcaaaa agctcttgat atttacggca gagccaccat atagagatgc
     6961 ctcagaccct aatgatgaaa tttctatatt tattcctttg ttaaaagagc taactaacat
     7021 atcttttgta atctgtaata tctcagggat atcactaatt atttggctat ttaaatatat
     7081 tatttcagga gcataagttg taatagcatt atttatagct attgttaagt aactacaaaa
     7141 ctcatgaata acttttttgg cattctggtt atcttcataa tatagttgct ttactatatc
     7201 agaatctatt ttaggaatat tttctaaaga agaaagctgt tcaaatacct ttttttctga
     7261 acaatactgt tctaaacagc cacgatttcc acaaggacat agtttaccat taggcatgat
     7321 gatagtgtga ccaatttctc cactcatacc atttctgccg ctatataatt tattatttat
     7381 tataatgcct gaaccaaatc cactgtgaat actgagacta agtagtgagt tatgtacagt
     7441 tgaaaaagta ttctcagcta aagctgttaa gtttgcttca ttttctatat gaataggaaa
     7501 gtcatacttt ttgctaagga tgctatataa gtcaatctca ttaagattat aatatggagt
     7561 aaacaatact ttattttcac aagtaatccc atgtatagcc aaagtaagac caattacctt
     7621 ataaggagtg tctattttgg atatgttata actatttata atttcatcta tcaattgtat
     7681 aacattgtct ttacttactt gtatatctgt taatttctta gaatttataa tagttccatc
     7741 taagtaagat agagaagaaa atatatagtc gtatccaatg tccatactta aagaaatccc
     7801 tgcacattta ttaaatacta ataatatggg ttttcttccg ccactatgag tactatttcc
     7861 aattcctatt tcatgaacta gagattcatc aataagtttt ttggtaatag cggatatagt
     7921 tgctttattc aatcctatag tagaagctat acttgcccta gaaataggac cattttttat
     7981 aatttgttca agtaccaatc tttcattcat ttctcgaata gtgtatttat cagtaaccaa
     8041 tttgatattc ctccttaaaa taatattgta atacttttta cacaaaaata aaaggttatt
     8101 ttgcattgac aaagataatt aaatatttta ttattagttc ataagttagt ttaatatact
     8161 aacaaaaata aagcaagtaa aatataccta aaatataaaa aaattaggat aggaaaacga
     8221 tagttatgaa gtggcattca aggagggatg aagttggagt atgtattagg tgtggatatt
     8281 ggtacatcag gtactaaaac agttttattt gataaactag gaaatattat aaaaagttgt
     8341 acatatgaat atactcttat acaagagaaa tcaggttggg cagagcagga tgcaaatgat
     8401 tggtggaaag ctgtagtcga atctataaga gaagtagttc aaagttcaaa tataagcagt
     8461 gaatgtataa aaggaattgg attatcaggg cagatgcatg gtctagttat gctggacaat
     8521 gaaggtaaaa cattgagaaa ctctataata tggtgtgacc aacgaacagt aaaagagtgt
     8581 gaggagataa ctgatttagt aggtgaagaa agactgattg aaataactgc taatccagcg
     8641 cttacaggat ttacagcatc aaagatatta tgggttagaa acaatgaacc agatatatat
     8701 ataaatacta ataaaatact tcttccaaaa gattatataa gatacaaatt gacaggtgaa
     8761 tatgctacag aggtatcaga tgcaagtggt atgcagttgc tcgatataag aaaaagagat
     8821 tggagcgatg aagtactaga aaagttaaat atagataaaa atcttttagg taaagtttat
     8881 gaatcacaag agattacagg ttatgtgact agagatgtag caagtttgac agggcttaaa
     8941 gaaggaacaa tagtggtagg aggagctgga gaccaagcag caggagctat aggaaatgga
     9001 atagttaaag atggagtagt ttcatctact ataggtacat caggtgtagt atttgcttat
     9061 acgaaagagc caaaaattga taaagaaggt agagttcata ctttctgtca tgcaatacca
     9121 aatacatggc atgttatggg agttactcaa ggagctggat tgtcattaaa atggtttaaa
     9181 gataatttct gtcaaagtga agtggaagtt tcaaattctt taggtgaaga tgtatatgag
     9241 attataaata atcaagtaag tcaagtacca acaggatgta atggattgct ttacttacca
     9301 tatatgatgg gagaaagaac tcctcatctt gacccttatg caagaggtgt gttctttgga
     9361 ttatctccaa tccattctaa aaaagaaatc gcaaggtcaa taatggaagg tgtttcatat
     9421 agtcttaaag actgtatgga tataatagag aatcttaata tagacgttaa tgaagtaaga
     9481 gcctcaggtg gaggtggaaa aagtaaagta tggagacaga tgcaagcaga tatgtttaat
     9541 caagatgtat atactataaa ttcaagtgaa ggaccagcac ttggagttgc aattcttgca
     9601 ttagtaggag ctggaatata tgaaaatata caaaaagctt gtgatgctat aataaaaact
     9661 tcaactaaat tagaaccaat aagtgaaaat gtagatacat acaagatata tcatagattg
     9721 tataaaagaa tatacaaatc tttgaaagat gactttaagt tattagatga agtagttaat
     9781 acaaaaataa ataattaaat tagcttaaaa agaaaaataa agatagaaaa tagttttaaa
     9841 ttaagaaaac atacgacata tattatatgt gtaaaatatt aggaggacat gaaatgagtg
     9901 aaatatttaa aggaatagga cagataaaat ttgaaggagt aaaatctgac aatgaattag
     9961 catttagata ctacaatcct gaacaagtgg taggtaataa gactatgaaa gaacacttaa
    10021 gatttgcaat gagctattgg catactttat gtggagaggg taatgaccca tttggagtag
    10081 gcacagtaga gagaccttgg aataatgtaa cagacccaat tgagatagca aagattaaag
    10141 ttgatgcagg atttgaattt atgtctaaga tgggaattga gtatttctgt tttcatgaca
    10201 gagatatagc tccagaagga agagatttag aagagacaaa taagatatta gatgaaatag
    10261 ttgagtatat aaaagttaat atggaaaaga caggtataaa gttattatgg ggaactgcca
    10321 atatgtttgg aaatccaaga tttgttcatg gtgcatctac aacatgtaat gcagatgtat
    10381 atgcatatgc agcagctcag gttaaaaaag ctatggaaat aactaagtac ttaggaggag
    10441 aaaattttgt attctggggt ggaagagaag gttatgaaac tttacttaac actaatacag
    10501 aacttgaaat ggataacttt gcaagattct tacaaatggc tgtagattat gctaaggaaa
    10561 taggattcac tggccaattc ttaatagagc ctaagccaaa agagcctact aaacatcaat
    10621 acgattttga tactgctact gttttaggat ttttaagaaa gtataatctg gataaatact
    10681 tcaaaatgaa tatagaagca aaccatgcaa cacttgcagg acatactttc caacatgaat
    10741 taaatatagc aagaataaac aatgttttag gtagtataga tgcaaatcaa ggagacctat
    10801 tattaggttg ggatacagac caatttccaa caaatatata tgatgcaaca cttgctatgt
    10861 atgaagtgtt aaagcaaggt ggaatagcac caggaggatt taactttgac tctaaagtaa
    10921 gaagagcatc ttttgaggta gaagacttat tcctagctta tattgcagga atggatacat
    10981 ttgcaaaggg attattaata gctcataaat tattagaaga tgaggtattt gaaaacttta
    11041 ctaaagaaag atatgcaagt tttagtgaag gtataggtaa ggatatagta gaaggtaagg
    11101 ttggatttaa agagttagaa tcttatgcac tgcaaatgcc agttataaag aataagtctg
    11161 gaagacaaga aatgctagaa gctatactta acagatatat atatgaagta gatacaattt
    11221 ctaataagta attgtgtagt aattaaactt ggatgtttga ataaaataac aggatatgtt
    11281 cttgttttta ttctaaaacg gacaaagata agtatttgta aaaattctca taatcatgat
    11341 aaattaagga tatagactta agtataatta gtttatatcc ttaaaatttc tataaaaaat
    11401 aatcatttct atagttatca atatttttaa ttatcaatac ctttctcaac taataaataa
    11461 aaatcagtaa agtatctaaa tttaagtcat tataatggat aaatttttta gcatatcttt
    11521 tttagtatat cactgataag aatttacttt caggatatag cagtaaaata gatatttgaa
    11581 tataattgtt attttataac tttcatgaaa taattttgaa aatacaaata aaaattttta
    11641 aatagaataa tagtggaata tatcttcaag aatttctttt aactgtttag gtgataataa
    11701 aataatgata caatgtatta aaatataaaa tctgaaagtg gatgagaatt acatgaaaaa
    11761 gaaagtatta tttttagtaa ttattttagc atttataatc ttattaggta attctactta
    11821 ttctcaaaag aatcagttgt ctgaagagga aaaggtggat gactttaatt atgtgtataa
    11881 tgttgtaaag acaggatatc catatctagg tgtaaataag agacttaata atattgattg
    11941 gttagcaaat aaggatgaat atacaaaacg aataaaaaac actgaaaatg atgaagaatt
    12001 tatagaagaa ctgtcatcta tattatctga tttaaataat aaacacacag aagtaataga
    12061 taataagaaa agatatgaac tttttaagaa atcatactct aataatgatt ggtatgattt
    12121 tcttaatgat aaaaaagttg tggatagata tgactctatg aatcttaaaa taaaaatgcc
    12181 agatgatatt tttgtaaaaa aagaattaat tttaaaggat gttattaagg gtcagattgg
    12241 atatatgtat ttaccatcaa tgtcatcaaa gaatggctct ataaataatg atttaaaaat
    12301 aattggagat tatattaaca ctttagaaaa acataaagct ttaattattg atataagagg
    12361 taatttaggt ggaagtgata ggtattggca gggaatcgta tctaaactca taaaaaatga
    12421 tgtcaaaata aatggttata gaatttatag aaataataat gaaatagtaa aaaaatatac
    12481 aaatgcaaga aatataaaat taaatcctgt agaaaattta ccagcaagtg taaaggaaaa
    12541 tgcacctaaa gaaattataa aagattttaa tgattttgaa gatacttcct atactataaa
    12601 atctacagat gattcaaaat ttaagggtaa tatatactta cttgttgata gaaaaatata
    12661 ttcatcatca gagtcatttg caatgttttg taaagaaact aaatttgcga ctttagttgg
    12721 tgaaactact ggcggagatg gagggtgtat agaccctgta ttgtttaatt taaaaaatag
    12781 tggtctaata gttagaatgg caagttgtat gtatttaaat aagaatggaa tatgtgatga
    12841 ggaatttaaa actattccag aatttaaagt aaaagattgt aaaaggactg ctgattttaa
    12901 agatgataat tgcataagaa aagcactaga acttgaaaat attaattatt agataaaaga
    12961 ataaaattaa aactacattt ttttaaacat caattatagc agtatttttt atagtcaatt
    13021 ttatgggcta aatagtaaat ataagaatac gctgtaattt aatgttgaat attggtataa
    13081 tatttatgac gatttttaat taaaggggat aatagtttat gagattagaa gaaatgattt
    13141 ttttaaatta taataaattg aatgatacag atttattaat atggaaatat ataactgcaa
    13201 ataaaaaaca ttgtagtaag atgtcaataa atgaacttgc tatgaaatgt aatgtgtctc
    13261 gtgcaactat tacaagattt gttaaaaaat tagatttaaa aggtttcagt gagtttaaag
    13321 tattattaag ctgggaatca gaaaaggttc atgtcataga aaatcagtca tttgatattg
    13381 catgtaattc aataattaag tatgttgaag atcaaaaaaa taaagattat gatgcattgt
    13441 gtaaacttct ttatgaatca agaacaatat acgcttatgg ttcaggtgat attcaaaatg
    13501 tggttgcaaa acagataaag agaatgttct tatcatgtca agaaataata tatgattttg
    13561 agggaagaac atttgatgat tctttttaca atattgtcag taaaaatgat gttatgatta
    13621 ttatatccct aagtggtgag aatgagaata cacttaatat tgctagaaga ttaaaattaa
    13681 taggaactaa aataatttca attacagagt ttaaaaataa tacattgact gatttaagtg
    13741 atgaatcaat ttatatttca gcgactaata tctcattttt acaaatgcac cctagttata
    13801 aattgacaat gttatatttt atattgattg agttattatt tattaaatat agtatttata
    13861 aaaggcatag aatgattaca gaagggattg attgcaaatt gtagtcattc ttttttttat
    13921 gagaatttga acataaaaat gtgcaaaaac ttatttgact gtgaataagc tccaaatgta
    13981 ccctaaagat tgtatatatt tattaacctg ttaaaataat agatatctaa ggccaaagat
    14041 aaactaaaaa tatgaggagg ggagtaattt atatgatgaa gaaaatacag cgttttggag
    14101 gggcaatgtt tacaccaaca ctattatttg cttttgccgg gataatggtt ggattctcaa
    14161 ttgtatttca aaatcagtca attatgggtt cacttgctac accagaaaat atttggtacc
    14221 aattttgggg tgtaatatct agtggagctt ggatggtatt taatcaatta ccattattat
    14281 ttgctatttc tttaccaata gcacttgcaa aaaagcaaca agcaagagct tgtatggagg
    14341 ctttagcaac gtatttgact tttaattatt ttgtaggttc tatgttaagt ttttggggaa
    14401 aaagctttgg agttgatttc gcagctgaaa taagtgctgg aagtggactt gtaagcattg
    14461 ctggtattaa aacattagat actggtatgg ttggtgcttt gttaatatca ggtattgtca
    14521 tttatattca taatagattt tatgataaag aactaccaga ttttattgga ttatttagag
    14581 gctcatcact tgtagttgca atttgtttct ttgttatgat accagttgca ttattaactt
    14641 gttttatttg gcctcatatt caaaatgtta ttagacattt gcaaacgttt tttataaata
    14701 gtggaaatat aggagtttgg tgttatgcat tcttacaaaa gattttaata ccaactggat
    14761 tacatcattt tgtatatgca ccaatttgtt atgatagtgt tgttgttcca ggtggtacat
    14821 cagtatattg ggctactcat attcaggact ttcaaacttc agctaagact ctaaaggaaa
    14881 tgtatccaat cggattttca ttatctggat tatcgaaggt gtttggttca ttaggtgtat
    14941 ttggtgcttt ctatgtaact gcaaagccag aaaaaaagaa aaaagtatta ggtttaatga
    15001 ttcctgctac tcttactgca gtattaactg gaattactga gccgttagaa tttacatttt
    15061 tatttgtagc accactttta ttcctagtac atgcattttt agatgcatgc ttgcaaacga
    15121 tttcgtttgc cttaggagtt gttggtgatt ttggtggagg aattattaac tgggttgtat
    15181 taaattggct tcctcttgga atgtatcact ggaaggtata tgttgttcaa gttgttgtag
    15241 ggattatatt ttcatttatc tggttctttt tatttacttt cttaattaag aagtttgata
    15301 tgaaaactcc tggtagagag gaagataatg aagaaacaaa actatatact aaaaatgaat
    15361 acttagaaac taaagatgaa aaaggaaata aattgagtaa agcctctcaa caagcatctg
    15421 aatacataaa attagttggt ggagcagaaa atgttgtaga tgttacaaac tgtgctacga
    15481 ggttgagatt aaccttgaag gatgactcaa ttatttctaa agaagaagat tttaaggtag
    15541 taggtgcaca tggtttagtg cataatggaa aagctattca gattattatt gggctttcag
    15601 taccaagtgt aagagaagaa tttgaaaatt tattataaag gagaaggaaa gatggaaaga
    15661 aaaagacaga ggatactaat tgctggtggg ggtagtactt atactgctgg aattgtaaca
    15721 atgttaattg aaagtgttgc taaatttcct attgaatcaa ttaaattata tgataataat
    15781 gatgagagac aaagaaaagt tgctgaagca tgtgcaataa ttgttagaga gaaaaatcca
    15841 gaaattaaat ttagttatac aacaaatcca gaagaagcat ttactgatat tgattttgta
    15901 atggcacaaa ttcgtgttgg tttatatgct ttacgtgaac aagatgaaaa aattccatta
    15961 aaatatgggg ttgttggtca agaaacttgt ggggcaggtg gaattgccta tggattaaga
    16021 acaataggtc caataatcga aatgattgat tatatggaaa aatattctcc aaatgcttgg
    16081 atgcttaatt attcaaatcc agcagctata gttgcagaag catgtcgtgt attaagacca
    16141 aattcaagaa ttattaatat ttgtgatatg ccagtatgtt tagaggaaat atttgctaga
    16201 attttaggtt taaattctcg taaagacttt gatgttagat attatggatt gaatcatttc
    16261 gggtggtgga caagtattaa ggacaaagaa ggaaatgatt taatgcctaa attacaggaa
    16321 tattgtgcta aaaaaggata tgaggaattt acacctcaag gtcaacacaa agaatctagt
    16381 tggttagaaa ctatgagagc agcaaaggac ttattagaaa tagaaccgac tacattacct
    16441 aatacttatt taaaatatta tttaatggct gatgaaactg ttgaacatgc taatccaaat
    16501 tatacaagag caaatgaaat tatggataga agagaaaagg atacattcga agaatgtgaa
    16561 agaattataa aaaatggcac agcaagggat acatggtttg atgcaagtga acattctcaa
    16621 tttattgttg aattagcttg tgcattagca tttaatactc aggaaagatt tttactgatt
    16681 gttcctaata atggagctat tgaaaatttt gcagatgatg caatgattga aattccttgc
    16741 cttgttggaa aagatatggt tgaacctatg tctataggta aaattccaac tttccaaaaa
    16801 ggtttaatgg aacaacaagt tgcttctgaa aaattagctg tagaagcatg gatagaaaaa
    16861 agttatcaaa aattatggca gtcgtttact atgagtaaaa ctgttccaag tgcaaaagta
    16921 gcaaaagaaa tcttagatga aatgattgtg gctaataagg atttctggcc aacttttaaa
    16981 taaggagaac aaaaacatga taacaaataa aataaaaaat ataacagcag tattaaaaga
    17041 tgaaaatata tttctttcag tggttatggt ttgttttcta atattacctg ttttatatat
    17101 agtgtattta gaattgacat cattatttac aaacatttca ttttcacaac ttttaaacaa
    17161 tgatgttaat gcaagtttaa atttaatctc taactttagt gcagtataca gtgcatatgt
    17221 tatttacaat ataaaaaaga ataaagagat aaaagaaaac atgattgctt tctatttagt
    17281 cttattaggg cagatattcc aaatttacac aataactatt gttatcatgt ttacctatat
    17341 ttataaattt gttggaatta aacaaatcat aagcagtatt aaagaactac aatggggaaa
    17401 gagctataag gctctttttt cctcaattgc agtatgctta atatcgttat ttgtaatgat
    17461 aattagaata aagttaatta tgtagaggag tgtctataat gttctttaaa agaaaaaaag
    17521 aagcaagtac aattaattca tacattgatg gaaaaataat taatcttgga gaaattcctg
    17581 ataaagtatt ttcaactaag gtaatgggag atggatttgc tatgatagca aaggacaata
    17641 ttcttaaatc accgactaaa ggagtaataa gttttattgc tcaaactaac catgctatag
    17701 gaattaaatt gcaaaatgat gttcaaattc ttattcatat tggattggat agtgcaacaa
    17761 caaaaaaaga aaactttaaa ttagaagtta aacaaggtca agaagttaat atgggggaaa
    17821 agttagtaga aattgataat aagttacttg aaaatacttt atatattcct ttagttattg
    17881 tagagaatcc taatacggta aaatatcatc tttcaaactt aaatcaggaa ggaaatagtg
    17941 gtattaaagt tatcaatttt gattgattat gattaataaa gcgattaaat ttaaatttat
    18001 catattctat tttttctcat atattatttt tgcctttgct tcaacaaaat tcacaccttt
    18061 cttatcaaaa ttaggttact cagcgtttga aagaggaatt atattatcga gctatgcaat
    18121 aaccaatata ttatttcaat tattatttgg agtattagct gataagtatc aaacaatgaa
    18181 aaaaattgtt ttaattagtt tatcagttta tggaattgca tcagttatta tgttttctac
    18241 tgaatctgca acttttataa tatacttatt acttgttgct ttatcaggag gattattaaa
    18301 tacttgctgt agtttatatg atacatggat aataggttgt ggagataata ttaataatta
    18361 tttgtcattt attaagactt ttgggtcgat tggatgggct attggaagta tggtagcatc
    18421 ttacttgatt cttagattct catattttgg attatctgta gcgattggtt taattgtagt
    18481 attacttatt ataaatatac tattattacc tgatattgaa aagattaata agaaaataaa
    18541 tgtaactaat aaagatatta ttgaattatt aaaagataaa aaatatatct tactagtatg
    18601 tattttattc ttattatact caatggtggt agcaaataac tgtactgtaa tagataaaat
    18661 gatagcttta aatgctacaa attctcagat atctttaaag tggtctttac agtcattatt
    18721 agagatacca acatatctgg ctggttctta tttattaaaa aaatatagca gtttaaactt
    18781 attaaaatta agtgctatta tgataacagt tcagtttcta ttatttgctt taacaaatga
    18841 ttcaaatatc attattatac tgtgtgtttt tcaagtgttt tctactcctt taattttaat
    18901 tacttcaaaa agattaatat ttgaagtttc tcctaaaaaa cttagaagta gtagccaatt
    18961 aatagcttta agtatattta tgggaggttc atctctgatt attccaactg ttgctggttt
    19021 tttgagtatt aatattgggt ataattatac attaatgata ttaagtcttt ttggatgctt
    19081 agcttatggc ttgatagtct tattgaatta tcttcaagaa taattgtttt aatatatagt
    19141 agtaatatca cttgtttata gtacctgtat ttgccacaat caaggttgta tttttggttt
    19201 tttatagaga agaattattg tatagattag aggcttctta ggggcttctt ttctttgttt
    19261 atacaaaaaa gtgaatcatg cttttatttt aagatatttc cactataatt ataatagtct
    19321 tccatatgtt acaaaagtgt aatgctaaca gttaaaatgt aatatttact taaggattta
    19381 tttatataaa acctttaaaa taaatatata ttaaaaaatt agcaactgga ggctattatt
    19441 atgaaagaaa tattaaaaat aaaaaatata tcaaaagatt atggaataaa aggatttaaa
    19501 acaaatgtgt taaaaaatat atctcttaca gtcaatgaag gtgattttat agcaataatg
    19561 ggtccatctg gtgcaggaaa gacaacattg ctaaatttaa tgtctacact tgacaaacaa
    19621 acttcaggag aaataatact agatggaatt aatatatcaa aagtaaaaaa taatgaacta
    19681 tcaaaattaa gaagagaaaa aatagggttt atatttcaag actataatct attagacaat
    19741 atgaaactaa tggacaatat agcacttcct ctagcattag gaaaaaagaa aagcaaggag
    19801 atagaagcta aggtattttc tatagctaaa aaatttggat tagaaaatca tttagataaa
    19861 tatccatatc agttatcagg aggacaaaaa caaagaggcg cagcagctag gtcattaatt
    19921 acaaatccag cagtcatatt tgctgatgaa ccaacaggtg ctttggactc taaatcagca
    19981 tatgaacttt tagaatcatt agaaaaaata aacagagaaa acaacgctac tattataatg
    20041 attacacatg accctctaac ggcaagttat tcaaatgaag tatatatgat aaatgatgga
    20101 aatataaagt gtaaattaaa caaaggaaat agtagaaaag aattttatgg aaaaattatg
    20161 gatatgctag cctctatggg aggtgagatg taagtgagta tacttggaat tgcttataat
    20221 aattttaaga gtaacataag aacttatcta gcatttttta tatctatggt tttttcagta
    20281 gttgtgctga ctaattttga attattaaga tatggagatg ctataaatgt gttacaagag
    20341 gaaaataaaa aatttacact atcagtgtta gtagctgtaa taatgatact atcagtattt
    20401 ttatttttct ttatatggta tgcaacaaat atatttttta agaataggtc taaagaaatt
    20461 ggaatattgt cctttatggg attagattta tatactatag gaaaaatata ttttgtagaa
    20521 aatatgctta taggaataag ttcttgtata acaggaataa ttatagggat aataacatct
    20581 agattttttc aagtagtgat aataaaatta tctggattta atataaaggt atctaatgga
    20641 cttagcatag aagctatact atatgctact ttaatcttta tttctatatt tataataatg
    20701 gctgtaaaag gttttataac aatatgtaga agtagtgtaa taaatctaat caatatatct
    20761 aaaaaacaag aaaaaatacc aaaggtagga ataggtatat atatattagc tatagtatca
    20821 cttatagtaa taggatatgg atactatctt tctacgaata taagaactgg agatataact
    20881 agtgtactac ctgttatagg tataataata gtaggtactt atggcttatt caaatcagtt
    20941 atgcctgtta tatttgatat tataatcaaa aataaaaaaa tattatttaa tggaaataat
    21001 ataattgcga taaacaatat aaactaccga ttaaataaaa actataaaac ttatgctata
    21061 atagctataa ttataactac aacaatatca actcttggtg cttcagttgc tatgaagcat
    21121 atacataaga atgcccaaga acaaagaaat gtgtacacta ttagcatagt ttcaatggat
    21181 aaagatgaag tgaataaaaa acaaatagag aacataataa aagatactaa taagataaag
    21241 tactccgtaa atccagaact aacaatctta aagaaaacag atataaaaga agcttatgat
    21301 acaacagata ctataatgaa atatagtgat ttttgtaata ctcttaaagt gaatggcaat
    21361 gataaagaat taaaagagta tggtgaaaga ttagttagtg gaaataatgt aatagagcta
    21421 aaaagtcctc aaacgatagc atcaatagct acaaaagaag tcaagacaaa acttgatggt
    21481 cagttatata atatttcaag gggagaagta aaagttccag tattagggac aggacttaat
    21541 caaagtatta tagtggtaaa tgatgataca tattttaaac taagagataa gggtcaacaa
    21601 gtatattttt atggtgcaaa ggtatttcaa gaagaaaata gccaagtaat gttcaacaat
    21661 attgaaaaga atttaagttt aaaaaatgga tatattcaga atggatataa agctcaaggt
    21721 gagagtcaat ggatgaagtt tgcatatgta gtgcttgtgt ttttattctt agtctttgca
    21781 attgtagctg gaagtataat atatatgaaa atatatagtg atgcatatga agataaagag
    21841 aaatacaaga ttttattaaa aataggtact acagaaaaag atataaatag agctatactt
    21901 aaagaagtag ctatatttta tactttgcca atgttaagtg caactatatc tagttatttt
    21961 gcattgagat tagcaggaga tttattgatg aacgatttat ctggtatata tatactaagt
    22021 ttagtgatat gtttgataat attcgtaata tatggagcag tatctgttaa taagtttaag
    22081 agtgtagtgt ataaaaatta gttgatatat taataaagag aaaggagatt cttgtaataa
    22141 gagtctcctt gttgattaac taaataattt gggtaataaa tttatataaa atatgttatg
    22201 atattaataa ttcatggcat agtgaaatat taggataatg gagaatatac aaatgtatag
    22261 aattttatta gtagaggacg atattgattt atcaaaagag attgcgttag cacttgaaaa
    22321 atggggattt aaagtagaat taattgatga ttttgaggta gtattagatg aatttatgga
    22381 taaaaaacca gatgtagtac ttttagatgt aaatttacca ttatataatg gattttactg
    22441 gtgcgaaaaa ataagagcta tttcaaatgt accattaata tttttatcat caagagattc
    22501 tgatatggat ttaataatgg gtataaataa tggagcagat gattatatta ccaaaccatt
    22561 ttctatagac atattggtta ccaaaataaa tggtataata agaagagtct ataattatag
    22621 tgattctaat agtattttgt attgtgaaga tttgatgttt gatgtgggga aagggattat
    22681 aaaacataag tataaggata aaagtataga gttgactaaa aacgaaataa aaattttaac
    22741 attattatta aaaaataaga atagggttgt atcaagggaa agtcttatga tgactctatg
    22801 ggataatgat gagtttgtga cagacaatgc acttactgta aatatgaata gattgagaag
    22861 taaagttaaa gaactaggtt ttgatgattt tataaaaact aagaagggga taggatatat
    22921 aatataatgc tagtaaaata tttaaaaggt aggtctaagt atattgctct acctttagtt
    22981 gtagttagta taataaatat ctatttattt gctatagata ttttaaaaaa tagatattca
    23041 gaattaatat acttaga
//
LOCUS       DAMJYN010000057        22964 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.058, whole genome shotgun sequence.
ACCESSION   DAMJYN010000057 DAMJYN010000000
VERSION     DAMJYN010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22964)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22964)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22964
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.058"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(755..1072)
                     /locus_tag="PC466_002468"
     CDS             complement(755..1072)
                     /locus_tag="PC466_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769837.1"
                     /translation="MDFGNINLILIGIIVIIGTTIIYLIKPKTAFCSKKYFNKLESIY
                     GNIDKKKTVKLEVLYRYVTGLEYISIGLFTRRLDITIIAIILVATITVILYYLVRKRY
                     ITI"
     gene            complement(1364..1933)
                     /locus_tag="PC466_002469"
     CDS             complement(1364..1933)
                     /locus_tag="PC466_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769838.1"
                     /translation="MKLRNPKIKKLLSVALLAALIGIPIGQTANAMEISNNVPSYIEN
                     NPTTIEDLEINDSQLPKPGTVTYIDINKLIKNLKENGIDTTLIENELYYRKAGTNKIV
                     WTKTGFDLYLSKGVALTLAGAGTGVAGLLAGAIPGIGQYLAAAIVGAITMHLGSNITS
                     GKIFKFKKMRYNKGGAYVTKYYLQSVRNQ"
     gene            2377..2767
                     /locus_tag="PC466_002470"
                     /pseudo
     CDS             2377..2767
                     /locus_tag="PC466_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902377.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
     gene            3087..3596
                     /gene="vanZ1"
                     /locus_tag="PC466_002471"
     CDS             3087..3596
                     /gene="vanZ1"
                     /locus_tag="PC466_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ1"
                     /protein_id="HDF2769839.1"
                     /translation="MKSRKHNITKGLFIVYIIILTWIILFKLQFDISSLETMNLRSIN
                     LVPFAGSLIINNRVDISEIILNVAIFVPFGIYVCMLKEEWSFIKKVIPIFITSLAFET
                     LQYIFALGASDITDLIGNTLGGIIGIAVFMLLSKIFKNNTIKIINVLALIVTIIVVLF
                     LGLVIFANL"
     gene            complement(3698..3892)
                     /locus_tag="PC466_002472"
     CDS             complement(3698..3892)
                     /locus_tag="PC466_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase"
                     /protein_id="HDF2769840.1"
                     /translation="MSVIVMCSRCGKEIDKYRNKYITYYEKNTNAEIKVCINCALDLL
                     EKTRENQELNIREFQDTIIL"
     gene            complement(4407..4799)
                     /locus_tag="PC466_002473"
     CDS             complement(4407..4799)
                     /locus_tag="PC466_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDF2769841.1"
                     /translation="MAALKSFEKPLTPEEEIEYLTKFKIENDKSAKDTLIERNMRLVA
                     YIAKKYNNSTEDQDDLISIGTIGLIKAIETYNIDKGTRLATYASRCIENEILMNIRSN
                     KKNKTQVSLQDPIGTDKEGNEINTTLYM"
     gene            5367..5729
                     /locus_tag="PC466_002474"
     CDS             5367..5729
                     /locus_tag="PC466_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769842.1"
                     /translation="MKIRKSGFISIECIISIAILYVAVYLVSTSLYNCYSFISRNISD
                     REMLSTAKKYIEDEKYRIQNSKYELIEDKIEKNYINGYEINSRIEQILDYYQCYEINI
                     EIKNEFKKLRFNSYVTRK"
     gene            5713..6429
                     /locus_tag="PC466_002475"
     CDS             5713..6429
                     /locus_tag="PC466_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769843.1"
                     /translation="MLLENKGSILIITLIIFSIISTVCIMCIGLIYTHNNMFELGYKD
                     IQLKEISLSGIEISVSNVLSCVEEAIDVSNNEDEFREYFLGNNMIECIKKIKDTSYSS
                     LEELSLKVENNTIYDRGDFFEFDIESNVREKEFLKAIKVRVKIKNPWIGIDIEDYMDK
                     SNNNKIDDKTFNNYKASENNEILNQFKNESENIRNQEVVEFTEEDEEYEEELKQNIIE
                     NIKKNFDEKKLVQVYKYRGV"
     gene            6449..6868
                     /locus_tag="PC466_002476"
     CDS             6449..6868
                     /locus_tag="PC466_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769844.1"
                     /translation="MTVIELIVSISIILLIVTLSFPKDNLENHKINLFARQLCSDIRY
                     VRRINMFSNYNTYIYYINQGKHEGYVLRKDGKNIKSIMLPKNAKIARSIEIIKFKSDG
                     SPQKASTIEIYNNRLRKTITITPVSGRVLLKEGKYET"
     gene            6858..7382
                     /locus_tag="PC466_002477"
     CDS             6858..7382
                     /locus_tag="PC466_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769845.1"
                     /translation="MKHKYGYLLLESVVSLSSMVIIILVLYSIFLSTINLKLKVEDKI
                     ELQQQSLEIIKSMEGIISNSMGIMNVSNYEETFKKTTSIKCRYVDENNNEESISNKEI
                     ILNERRNKLFVNSLNGESSQAGGYEIGDYVDEMYVLITNNGQYVNIKLKLSKRSQKYE
                     TDFKIKVWNFSESI"
     gene            7694..8251
                     /gene="efp"
                     /locus_tag="PC466_002478"
     CDS             7694..8251
                     /gene="efp"
                     /locus_tag="PC466_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HDF2769846.1"
                     /translation="MVSAGDFRKGVTFEKDGQPCLVVDFQHVKPGKGAAFVRTKYKNL
                     KTGAIREESFNPSEKFPKAVIDTRQMQYLYNDGELYYFMDQENFEQIPLNYEQVEDAI
                     KFLKENEVATIRFYQGQPFQVEAPNFAELEVTDTEPGIKGDTASNVTKAATVETGAVV
                     QVPLFINTGDKVKIDTRTGEYLSRV"
     gene            8343..8798
                     /locus_tag="PC466_002479"
     CDS             8343..8798
                     /locus_tag="PC466_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HDF2769847.1"
                     /translation="MKHLYEEVAYLKGLAEGLEISAESKEGKMIHKIVDALEVFADAI
                     VTLDEEQEELQDFVESIDEDLADLEEDIADMEEDLYEEDDDEDDEDFSYIEMECPNCG
                     ELVEIDEDLLYDDEVDVVCPDCKAVILSSEDDCDDDCTCGGCPSCDDRE"
     gene            8961..9671
                     /locus_tag="PC466_002480"
     CDS             8961..9671
                     /locus_tag="PC466_002480"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HDF2769848.1"
                     /translation="MKISKKLLDNIQRFENVINYKFKNKEYILEALTHSSYSNENKKY
                     NFNERLEFLGDSVLGIVISDYLFNEEANLPEGELTKLRANIVCEDSLSEVANDINLGI
                     HMLLGRGEEATGGRHRTSILADAFEAVIAAIYLDGGFESARQFILHHMENIIYDSRKG
                     NIFRDYKTHLQEVLQGNGENNIWYRLIEEKGPDHNKRFVMEVGINDDVLGIGEGKSKK
                     EAEQLAAKIALKKKLWEK"
     gene            9725..10795
                     /locus_tag="PC466_002481"
     CDS             9725..10795
                     /locus_tag="PC466_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HDF2769849.1"
                     /translation="MKKRIIPIFVPHKGCPHDCIFCNQKKITGVSTDVTSEDARNIIE
                     ECLETIDKDADVEIAFFGGSFTAIDIDIQKSLLSVAKEYVEKGLVKDIRMSTRPDCID
                     EDILSMLKEYKTSIIELGVQSLDEKVLLDSIRGHQSEIVYKSSKMIKNSGIKLGLQMM
                     IGLPADTEEKCIFTAKKFVELKPDCVRVYPTLVVKDTGLEKLMEQNKYNPFTLEESVN
                     IVKKVLVLFYVNNINVIRVGLQATDDIQIGKAVLAGPYHPAFRELVEADMIKDYLEFV
                     ILQNKNIKQMLVKSNKKNISKIIGNKKTNVKYMEEKFGVLLKTQESDLDINQLEIVLD
                     GKSLISANMRDIHRKLYDIYDL"
     gene            10823..14377
                     /gene="smc"
                     /locus_tag="PC466_002482"
     CDS             10823..14377
                     /gene="smc"
                     /locus_tag="PC466_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HDF2769850.1"
                     /translation="MYLKRLELKGFKSFPVKTDIIFKEGITAIVGPNGSGKSNISDAV
                     RWVLGEQSIKSLRGDKLEDVIFAGTDTKKPMNYCEVALTIDNSENQLELDFTEVTIRR
                     RAYRNGESEFFLNNKSCRLKDIKEVFLDTGIGKDGYSIIEQGKVDEILSNNPLSRRKV
                     FDEACGISKYRYKKQEAERNLSNTKENLERIDDVYIEIENQLKPLFNQQTKAKKYLEI
                     SEKLKILEVNSFIREIEGIEKELSEVNEHRKVIEKELNEKEEQKNVVEKKQEDINKEV
                     EVLQDVIEKSVDYINSIKGVISKKESQINLIKERIRNFTNEISRKNLEINDIKEKLNE
                     NKQYIKELESNKLSGSEELSTLQENIKVLEASKDKQKIKLESLNNEIELLKESIIDIL
                     NKKQEFSNKLSTLNANKENMNIRDENINSEITELNKNIEIKSSELDTINKEFNMQNEN
                     LKNVNNRHKELSINLQDSISEHNKLEDEIQKSKYNLNGYNSKLNVYIDMENHYEGFNR
                     GVKEVLKNKNLKGVHGALGQIINVPEKYEKSIEAALGAYMQNIITDNEFSAKSAINYL
                     KQNNLGRVTFLPLNIIKSNKVSLGNLKANTKFIGIASDLITFDEKYRNIIENILGRTI
                     LINNIDEGIKFAKETGHRFKIVTLDGEILNPGGSLTGGSLKTNGNILSRKRYINEYTE
                     KISNIKNEISHLELKRESLDKDVKNIKNEIDSHESKIKDLEKSIIIKSTSIKNVESEI
                     ESLKGSITKLENEKNDLNSNLNYTLEKSDDVRKDMEELDDLYNKNKEKIDALNEEIKR
                     YNDLYDKEKSEFDELNLSLVKKTEAYNSIVRDIKRISGENCELEEKNKQLEESLNYEE
                     HEIIKLQDSIATEEKEKENLTKQLGDSNRNLETRKIAKDDLKNSFDEINKELKTIDRQ
                     HIELKESLFKVGGRLERLKTSQDTYINKLFEQYDMTLVQALEIKDEDLDIDRKFLESL
                     KREIRSLGNINIGSIKEYEEIKERYDFYSEQKQDLEESMEEIEKLIHTLEENMKSEFE
                     IKFEEISKNFKYVYKRLFGGGCGELTILDKENLLESDILITAQPPGKKMKNLNLLSGG
                     EKALTAISILFAILITKPTPFCILDEIEAPLDDANIFRFGEFLKDLSKETQFISVTHR
                     RGTMEAADYIYGVTMQEKAISKVISLKLKEAQEITDII"
     gene            14404..15684
                     /gene="ftsY"
                     /locus_tag="PC466_002483"
     CDS             14404..15684
                     /gene="ftsY"
                     /locus_tag="PC466_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HDF2769851.1"
                     /translation="MLKKLFGFGKDKEKEIEKKDAEEEIEVEDSVDSLENLEETIFSG
                     LEEEVIDKVEDIEEKTEESVNNEGTEEIENFEKIEVEMDSNAKEVENISNNDSQEEII
                     EELENYDEIESKEIEDKEDKKVNLFERLKQGLTKAKQGITDRIDEVLKSYTKIDEELL
                     EDLEEILITADVGVNTTMDIIERLRDKIKQKGITEPIKVREELKSIVEDILTNENSTL
                     DIEPAPCIILMVGVNGVGKTTTIGKLANRYKKDGKKVLLAAADTFRAAATEQLEIWAN
                     RTNVDIIKHQEGADPGAVVFDAIKAAKARKTDVLICDTAGRLHNKANLMNELGKVFKI
                     VDREFPEAKREVLLVVDATTGQNAVVQAKTFKEVADITGIVLTKLDGTAKGGVVLAVK
                     SEVDVPVKLIGVGESVEDLQDFNAKSFSDALFGN"
     gene            15787..16155
                     /locus_tag="PC466_002484"
     CDS             15787..16155
                     /locus_tag="PC466_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HDF2769852.1"
                     /translation="MNIEKMVEIGLLFEQYKELLTDKQKEIVALYYEEDYSLGEISEN
                     LNVSRQGVYDTLKRSEKILRDYEEKLHLVSKIQEQEKNIKIIKDKIIDIKEDLLHNRD
                     CANLIPKLENIEDVCREMIK"
     gene            16152..17504
                     /gene="ffh"
                     /locus_tag="PC466_002485"
     CDS             16152..17504
                     /gene="ffh"
                     /locus_tag="PC466_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HDF2769853.1"
                     /translation="MIFEGLSDKLQGAFSKLKSKGKLTEVDVKNAMREVKLALLEADV
                     NFKVVKDFIKKVQERCVGQEVMQSLTPAQHVIKIVNEELTSLMGDVQSKVMISSKPPT
                     ILMMVGLQGAGKTTTAGKLGGYFKKQGKKPLLVACDIYRPAAIKQLQVVGEKLDIPVF
                     NMGDKENPVNIAKAGLSHAIKNANDLVIIDTAGRLHIDEVLMAELKSIKSEVKPHEIL
                     LVVDSMTGQDAVNVAESFNEALGVDGVVLTKLDGDTRGGAALSIRAVTQKPIKFMGMG
                     EKLDDIEPFHPDRMASRILGMGDVLSLIEKAQENIDLEKAKELEQKIKKQELDFEDFL
                     QQMEQIQNMGPLDKILGMIPGMGNVKDQLGDVDLNGKEMKRTKAIIQSMTTYERRNPG
                     VLNASRKKRIAKGSGTSVQDVNRLIKQLNEMKKMMKMFAGSQKSMKKRGGLGGLPFFK
                     "
     gene            17542..17814
                     /gene="rpsP"
                     /locus_tag="PC466_002486"
     CDS             17542..17814
                     /gene="rpsP"
                     /locus_tag="PC466_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HDF2769854.1"
                     /translation="MAVKIRLKRMGANKKPFYRIVVADSRAPRDGKFIEEIGYYNPIS
                     EPKQVRINDEKAIKWLATGAQPTEVVKKLLVKNGVIEKFEASKQAK"
     gene            17879..18106
                     /locus_tag="PC466_002487"
     CDS             17879..18106
                     /locus_tag="PC466_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HDF2769855.1"
                     /translation="MKELVVDIAKALVDNPDSVVVEEFEDNDGIVLKLTVAQEDMGKV
                     IGKQGRIAKAIRTVVRSVANRENIKVSLEIV"
     gene            18214..18729
                     /gene="rimM"
                     /locus_tag="PC466_002488"
     CDS             18214..18729
                     /gene="rimM"
                     /locus_tag="PC466_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA processing protein RimM"
                     /protein_id="HDF2769856.1"
                     /translation="MKEKLTHFKVGQIVNTQGLKGEVRVYPLTDDIERFDELKDFYLG
                     KDLNNKLAVEKVRYKGSMVIMKIKGIDSIEKAEKLKNKFMYVSREDSRELEEGEFFIA
                     DMIGMEVLTVDGKYVGILEDVLQYSANDVYVVKGEEDKEFMIPAIKKFVPTIDIDERK
                     MIIDPIKGMID"
     gene            18738..19433
                     /gene="trmD"
                     /locus_tag="PC466_002489"
     CDS             18738..19433
                     /gene="trmD"
                     /locus_tag="PC466_002489"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HDF2769857.1"
                     /translation="MRFHIMTLFPEIFNSYMDESIMKRAVEKGIIEVYIYNIRDFSNN
                     KHKKVDDYPFGGGVGMVMTPQPIYDTYKHIITTHNISNPSVIYLTPKGKVYNQSIAKQ
                     MSLKEDIILLCGHYEGVDERIIDLIVTDEISIGDYVLTGGELPALIMIDSISRLIPGV
                     LNQEESFEEESFKDNLLEYPHYTRPRDFEGLKVPEVLLSGNHKKIDEWRREESIRITK
                     ERRFDLYKKSNEK"
     gene            19618..19968
                     /gene="rplS"
                     /locus_tag="PC466_002490"
     CDS             19618..19968
                     /gene="rplS"
                     /locus_tag="PC466_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HDF2769858.1"
                     /translation="MNEMLRAIEQEQLKNEVPNFGPGDTVKVHVRIIEGKRERIQVFE
                     GVVLKRQGGGARETFTVRKMSFNVGVERTFPVHSPKIEKIEVTRKGKVRRAKLNYLRG
                     RVGKAAKIKEARNK"
     gene            20289..21185
                     /gene="ylqF"
                     /locus_tag="PC466_002491"
     CDS             20289..21185
                     /gene="ylqF"
                     /locus_tag="PC466_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HDF2769859.1"
                     /translation="MSNEYEEYLMDDNLHINWYPGHMKKTKELVKNNLKLIDVVIELL
                     DARIPFSSKNPDIDRLVGDKPRVVVLNKSDMADRDKLNQWIEYYKKINIKAIPVDTIK
                     GVGINNIIEECKNVTREKMSSLKDKGRKERAIRIMIVGVPNVGKSSLINKLTGRKSTQ
                     TGDKPGVTKGKQWVRLKGNLELLDTPGILWPKFEDQEVALNLAFSRAIKDEILDTETL
                     ALRLIEKLMKIEPEKLKARYKLDCLGETPIETMDMIGHKRGFITGKKELDYTRIAATV
                     LNEFRDGKIGNITLEVPENVKR"
     gene            21574..22866
                     /gene="brnQ"
                     /locus_tag="PC466_002492"
     CDS             21574..22866
                     /gene="brnQ"
                     /locus_tag="PC466_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HDF2769860.1"
                     /translation="MGKTKDVIVFGFALFAMFFGAGNLIFPPYLGIITGPEWLIAFLG
                     FTFADAGLALLAVMATAKFDGNVVEMFKRCGMKLGILIGCADILCIGPFLAIPRTGAT
                     TYEMGIMPLFGTSIPVLLFCILFFALSYVLTIRPSKVVDIVGQFLTPALLIALAFIII
                     KGIISPLGDIVDKPMIPNVFAEGIGQGYQTMDAFAAIALASVLIVSLNDKGYSTISDK
                     LKMIGKAGVLACGGLALVYGGLCFLGATVSTMYGTDAVQSQVIVNITEGLLGNVGKAI
                     LAVVVSLACLTTSIGLTSATGQYFSRLTKGKLSYEKIVLAVSVFSAVVASFGVGTIIK
                     IASPILSIVYPPSIVLIILAFFNEKIKNDNVYKGAVYMSLLVSILTVISSYGVDVPVV
                     KSLPLHSLGFNWVVPVIIAGIIGNFIPSKSQSNTLGTN"
BASE COUNT         9502 a         2223 c         3979 g         7260 t
ORIGIN      
        1 tttttagggt ataattttta aaattatatt ctactatcaa aagatatgaa taaatgattg
       61 tatatattat atcaattttt atatttcata gtccattttt tcatcacatt ttcgcttgtc
      121 aagaataata tctttaagag tgaagcgttt gatgtaaatc tggactttgt ttttgagaca
      181 tttttgaaat atttattaaa tccttcgatt atacttgtaa tatatattat agatattact
      241 tattttagta aaactaaagg ctgatgctac aacattccag ttatttccaa acgttttaat
      301 ttctgaagta tactgtttac attattttta atctatttta tctaaagtcg ataaggcttt
      361 ttattcatta actgacctat atacagattt aaaatcactt attaattctt ttgagtcctt
      421 gtatgaaaca tatttaaagt atttcttatc taatgtatta aacatttttg tattacagaa
      481 tgaggataac ttgtagctat tgtctctttg aaataagtca tctgtattta ctcctaaaac
      541 tacttatatc tgtagatttt ataagttctc catcttatat aatttctttg attaattgtt
      601 ttcttaaatt attcataaaa aaatctccgt tacgatattt gattatattt aaatcattgc
      661 cataaagaag acttttatta actttgaaaa acaaattatt ttacattact ggtgattagt
      721 tgctactttc ttttgatatt aattctatta gattttatat agttatatat ctctttctaa
      781 ctaagtaata taatattact gttatagtag ctactaatat tattgctatt attgtaatat
      841 ctaatcttct tgtaaataag cctattgata tatactcaag acctgttaca tagcgataaa
      901 gtacttctag tttaacagtt tttttcttat ctatatttcc atatattgat tctaatttat
      961 taaaatattt tttactacaa aaagcagttt taggtttaat taaatatatt attgtagttc
     1021 ctattataac tattattcca ataagtataa gattgatatt tccaaaatcc atagcagata
     1081 cctcctgtta aatttacttt tcttaatcaa agtatatcag taacacaagt ataaagagta
     1141 tctaaaatat tacaaatatt aaatgagaaa aagatggtag gttaacccca ccatcttatt
     1201 ttttatctat taataaatga tgctacaaaa gttagtataa aaaatgaaac aaacaatata
     1261 atgaacttgt gtaatttact tagttgaaat actttattac aaaagaataa aactagtgct
     1321 gagataattg caaaaagtag atattttata atcattttat cacctattga tttcttacag
     1381 attgtaagta atatttggtt acataagccc cacctttatt ataacgcatt tttttaaatt
     1441 taaagatttt tccagatgtt atatttgaac caagatgcat tgtaattgct ccaactatag
     1501 cagctgcaag atactgtcct ataccaggaa tggcaccagc caaaagccct gcaacccctg
     1561 taccagcacc agctaaagtt aatgcaactc ctttagaaag atataaatca aagcctgtct
     1621 tagtccaaac tattttattt gttccagctt ttctataata taattcattt tcaataagag
     1681 tagtgtcgat accattttcc ttaaggtttt taattagctt attaatatct atgtatgtaa
     1741 ctgtacctgg tttaggtaat tgagagtcat tgatttccaa gtcttctatt gttgttggat
     1801 tgttttctat ataacttggg acgttatttg aaatttccat tgcattggct gtttgtccaa
     1861 taggtatacc tataagagct gctaataatg ctactgataa caatttctta atctttggat
     1921 ttcttagttt cataaaatac ctccatttta aattagttat atatcaaaga tatatattat
     1981 tattgtagaa tataattctt aagaattaac tacattaaat attaataaaa aatatagtaa
     2041 aacttaagaa tacatataat aaaacttaat ataaattaag tatatgaaat aaatatcctg
     2101 tatttaagct tatagattat aatgaaatat aatacatatt ataataataa aacgaactaa
     2161 aattatcaca ctaaagcata aaacatactc taatcatgtt agataaattt ttgaatatat
     2221 aatccaaaag tactctctaa agtagagtac ttctttttta ttaattattt ttatatggaa
     2281 taaattggaa tattatattt gttccaatct gattgattac atactattat tagtataaaa
     2341 tttaattata cataaattgg taagaggtgt aaactaatga agattaataa attaccacat
     2401 gcagaactaa aactaatgaa gtatatttgg ggagcagatg atgtattagc ctcaagagat
     2461 atcatagaag caatgaagtt gaaatacgat tggaaaaaga gcacaacatt gacattttta
     2521 aaaactttag tagataaggg atttttaact acttattaag gtagatagat gtacgcatta
     2581 tactatagct ataaaagaga aagattactt aaaagttgag acaaagagtt tttttagttt
     2641 tatgcataac aattcattta agagttttat ttcagcacta catgatgatg aagttttaga
     2701 tagtaagagc ttggacaaat tagaagaata ctttaaaaat ttgaaagaag aagatattga
     2761 tgactaataa agctatcagt atctttttag tttgagacaa ttgagagtag cgtttggatt
     2821 taatgttagt tttatgtgat ggtaaaacat tatataaaga aaagtgatta tttccttagt
     2881 gtttgatagt aaaaaatata gagaataata ccaattaaaa tttaaagata tatgaaatac
     2941 tacaatagct taaatcatgt aaatatgata aagatattga aattataaaa ggaatataat
     3001 tttagaagaa atagttgaca gataaattac cttactatat tattgtatta ataaaataat
     3061 acaataatat agtaaggagg taataaatga aatctagaaa acataatatt acaaaaggat
     3121 tatttatagt ttacataatt attttaacat ggataatact atttaagttg caatttgata
     3181 tctcatctct tgaaaccatg aatcttagaa gcataaactt agtacctttt gctgggtcac
     3241 ttataattaa taatagagta gatatatcag agattatatt aaatgtggct atatttgtac
     3301 catttgggat atatgtgtgt atgctaaaag aagaatggag ctttataaaa aaagttatac
     3361 ctatttttat aactagttta gcatttgaaa cacttcagta tatatttgca ctaggtgcaa
     3421 gtgatataac cgatttgata ggaaacacac taggaggaat cataggaata gctgttttta
     3481 tgctattatc gaaaatattt aagaataata ccataaaaat tatcaatgta ttggcattga
     3541 ttgtgacaat tattgttgta ttatttttag gattagttat ttttgcaaac ttatagaaat
     3601 aagtatatag gtttagctta aaatagaacg taagatacag ttacatataa aattatttac
     3661 acataaaaag cacctatata ggtgctttcc taaattatta aagaattatt gtatcttgaa
     3721 actctcgtat gttcaattct tgattttctc ttgttttttc taataaatct aatgcacaat
     3781 ttatacaaac tttaatttct gcattggtat ttttctcata ataagttata tatttatttc
     3841 tatatttatc tatttctttt ccacaacgac tacacattac aattacgctc atatcttagt
     3901 tcctccatct ctaattattc ttaatatatt caatagtatc acttttctga aaataatgat
     3961 tgttaaaact gtatcaaatt tagatttact ttttattata atgcatttta ataaaaaaat
     4021 aaaggttatg ggtaaaatat ttatagaaaa aagtatatta ttgaatagat tataaaattt
     4081 tattattttt catcagtctt aaatacacat taatatctat aaaatgacaa aataaaaaat
     4141 actatttaaa tagagattaa aaaattgatg cgaagtattt gtttgctata tgaataacaa
     4201 tttatttaga agttttgatt tgacactgta taataataaa gtaattgcta aaaaagtttg
     4261 atgatttgga tgtattttta gaaattagaa aaatatatac ttactgacta atgataatct
     4321 tatatatatt ttagtttgag tgatttaaga aaagtgtttt gaaaggggat tattttatag
     4381 aataaatata tatatatagt agaaaattac atataaagag tagtatttat ttcattacct
     4441 tctttatctg ttccgatggg gtcttgtaga gatacttgag ttttattttt tttgttagat
     4501 ctaatattca ttaaaatctc attttcaata catctagaag catatgttgc taatcgagtt
     4561 cccttatcta tgttataagt ttctatagct ttaattaatc ctattgtacc tatggatatt
     4621 aaatcatcct gatcttccgt tgaattatta tatttctttg ctatataagc tactaatctc
     4681 atgtttcttt caattaatgt atcttttgca cttttatcgt tttctatttt aaatttagtt
     4741 aaatactcaa tctcttcttc aggggttaag ggtttttcaa aagatttaag agctgccaat
     4801 aggtcacccc cttttcaacg gtcactttaa attatatgaa ggagacttat ccaagttgac
     4861 tgttatctaa taaaataata tgcatatttt tagaatttaa aacatatatt tgcaaacttt
     4921 tgaatggaat atgacataaa gagtgggaat ttaaatttaa gtttttgttg tatatatatg
     4981 aaacaaggcg aagaaattat tgatttataa agtataaatt ggaattgagg tgtcaataaa
     5041 tataaaagga aatagtattt atatatgttt tggtgttgag gtaaaagatt aatgcaaagc
     5101 attagagtct ataaaaatat gaatatagga ggtgtaattt tacaatactt aaaaaagtaa
     5161 atgtaattaa ttgtttgtat aaagttgatt acaagcaaaa agtatcagtc atagttaatt
     5221 ctgttaagga tgaaggtggt gtgttaattt atatatgtat gggaagaaat tttgattaca
     5281 atgaaaaaac ttacaaaaga tatttatgaa aaaacttata gttaaatgtt tatatataaa
     5341 atattattta ggggttgttt ttattattga aaataagaaa gagtggtttt atatcaatcg
     5401 aatgtataat aagtattgct atattatatg tggctgttta tttagtttct acatcattgt
     5461 ataattgtta tagttttatc agtagaaata tatctgacag agaaatgtta agtacagcaa
     5521 aaaaatatat agaagatgag aagtatagaa tacaaaatag taagtatgag ttaattgaag
     5581 ataagataga aaaaaattac ataaatggat atgaaattaa cagtagaata gagcaaattt
     5641 tagattatta tcaatgctat gaaataaata tagagataaa aaatgaattt aaaaaactga
     5701 ggtttaatag ctatgttact agaaaataaa ggctctatat taataataac attgataata
     5761 ttttctatta taagtactgt gtgcattatg tgtataggtt taatttatac acataataat
     5821 atgtttgagt taggatacaa ggacattcaa ctaaaagaaa tttctttaag tggaatagaa
     5881 atatcagtaa gtaatgtact ttcttgtgtt gaggaagcta ttgatgtatc taataatgaa
     5941 gacgaattta gagaatattt cttaggaaat aatatgattg aatgtataaa aaaaataaaa
     6001 gatacatctt atagtagttt agaagaactt tctttaaaag tagaaaataa tactatttat
     6061 gacagaggag atttttttga atttgatata gaaagtaatg ttagagaaaa agaattttta
     6121 aaagcaataa aagtaagagt gaaaatcaaa aatccatgga taggaattga cattgaagat
     6181 tatatggata aatctaataa caataaaatt gatgacaaaa cattcaataa ttataaagca
     6241 tctgaaaata atgaaattct aaatcaattt aaaaatgaaa gtgaaaatat aaggaatcaa
     6301 gaggttgttg aatttacaga agaagatgaa gaatatgaag aagaacttaa acaaaacata
     6361 attgaaaata taaagaagaa ttttgatgaa aaaaaactag tacaggtata taagtatagg
     6421 ggtgtataac tttgaaaaaa gaaggaatgt gactgtaata gaattaatag tatctatcag
     6481 tataatactc ttgatagtta cattatcttt tccaaaagat aatcttgaaa atcataaaat
     6541 aaatttattt gcacgtcaac tttgttcaga tataaggtat gttaggcgaa ttaatatgtt
     6601 tagcaactac aatacatata tatattatat aaatcaaggt aaacacgaag gttatgtatt
     6661 gagaaaagat ggtaaaaaca ttaaatcaat aatgctacct aaaaatgcaa aaatagctag
     6721 aagtattgaa ataataaagt ttaaatctga tgggtcgcct caaaaggcgt ctacaataga
     6781 gatatataat aatagattaa gaaaaactat aacaataaca cctgtaagtg gaagagtact
     6841 tctgaaagag ggaaaatatg aaacataaat atggttactt gcttttggaa agtgtagtat
     6901 cattgtcttc aatggtgata attatactag ttttatattc tatatttttg tctacaataa
     6961 acttaaagtt aaaagtagaa gataagatag aactacaaca acaaagtctt gaaatcataa
     7021 aatctatgga aggaattatt agcaattcta tgggaataat gaatgtatct aattatgaag
     7081 aaacatttaa aaagacaacg tctataaaat gtagatatgt agatgaaaat aataatgaag
     7141 aaagcataag taataaagaa attatattga atgaaagacg aaataagtta tttgtaaatt
     7201 ctttaaatgg cgaaagtagt caagcaggtg gttatgaaat tggagattat gtagatgaga
     7261 tgtatgtatt aattactaat aatggtcaat atgttaatat taaattgaaa ttatcaaaac
     7321 gtagtcaaaa atatgagact gatttcaaaa taaaagtatg gaattttagt gaaagtatat
     7381 aaaaatacat aaatttaaga taaagaaatg acatcaataa gtcatataaa atataattat
     7441 tgagaactat ataactaaat aatatcaata tgtaaagtgt atagattaag aatatagagg
     7501 ataataataa aaatatagaa taagtaattt gccaaatact tgtttatatt gtataactta
     7561 tgatattatg atattagtaa aaatttgtaa tcctgacttg acagaattca agtaagagat
     7621 ataattttaa aggcatagta atgtaaaatt tactaaaaaa taagaaattt attttaatat
     7681 ggaggaacaa aaaatggtat cagcaggtga ttttagaaaa ggtgttacat ttgaaaaaga
     7741 tggacaacca tgtttagtag ttgattttca acacgttaag ccaggtaaag gagctgcttt
     7801 cgttagaact aaatacaaaa acttaaaaac aggagctata agagaagaaa gtttcaatcc
     7861 aagtgaaaaa ttccctaagg ctgttataga tacaagacaa atgcaatatc tatacaatga
     7921 tggtgagtta tattatttta tggatcaaga aaattttgaa caaataccat taaactatga
     7981 gcaagttgaa gatgcaatta agttcttaaa agaaaatgaa gttgctacaa taagatttta
     8041 ccaaggacaa ccattccaag tggaagcgcc aaactttgca gagctagaag ttacagatac
     8101 agagccaggt ataaaaggtg atacagcaag taatgtaact aaagcagcta cagttgaaac
     8161 tggagcagtt gttcaagttc cattatttat aaatactgga gataaagtaa agatagatac
     8221 tagaacaggt gaatatttat caagagtata aaaatttatg tatataaaag cttatatgtc
     8281 ttaataatat aagatatatg agcttttagt ttatatataa aaaagaaagc gaggggtgtt
     8341 acatgaaaca tttatatgaa gaagttgcat acttaaaagg cctagcagaa ggactagaaa
     8401 taagtgctga aagtaaagaa gggaaaatga tacataaaat agttgatgca ttagaagtat
     8461 ttgcagatgc tattgtaaca ttggatgaag aacaagaaga acttcaagat tttgttgaat
     8521 ctatagatga agatttagca gatttagaag aagatattgc tgacatggaa gaagatcttt
     8581 atgaagaaga tgacgatgag gatgatgagg acttcagcta tatagaaatg gaatgcccaa
     8641 attgtggaga gttagtagaa atagacgaag atttgttata tgatgatgaa gtagatgttg
     8701 tttgtcctga ttgtaaggct gtgatattat catcagaaga tgattgtgat gatgattgta
     8761 catgtggtgg ttgtccaagt tgtgatgata gagagtaaaa attcataaga attaaaactg
     8821 cctatgatgc ctatgagata ttttgcttca taggtagttt tatttttatg aggaagggta
     8881 ttatgtattt tggttttgca atacttggac aaaaatagta cactagaatt tatagaatag
     8941 gattttggag ggatgtaaat atgaaaataa gtaaaaaatt actagataat atacaaagat
     9001 ttgaaaatgt tataaattat aaatttaaaa ataaagaata tatactagaa gctcttactc
     9061 atagttcata ttctaatgaa aataaaaaat ataattttaa cgaaaggttg gaatttttag
     9121 gggattcggt tttaggcata gtgataagtg attatttatt taatgaagaa gctaatctgc
     9181 ccgaagggga actaactaaa cttagagcaa atatagtttg tgaagattcg ttaagtgaag
     9241 tagctaatga tataaattta ggtattcata tgttattagg tagaggagaa gaagcaacag
     9301 gaggaagaca taggacttca atattagcag acgcatttga agctgtaata gctgctatat
     9361 atcttgatgg aggttttgaa agtgcaagac agtttatact tcatcatatg gaaaatataa
     9421 tttatgattc aagaaaagga aatatattta gagactacaa aacgcatctt caagaagtgt
     9481 tacaagggaa tggagaaaat aatatctggt acaggcttat agaagaaaaa ggaccagacc
     9541 ataataaaag atttgtaatg gaagttggaa ttaatgacga tgtattgggt ataggagaag
     9601 gaaagagtaa aaaagaagct gaacagttag ctgctaaaat agctttaaag aaaaaattat
     9661 gggaaaaata aatataatat gtaaaaatat aaaaagaaat atttatatta gaaggatgtt
     9721 gtagatgaaa aagagaatta tacctatatt tgttcctcac aaaggatgtc ctcatgattg
     9781 catattttgt aatcaaaaaa aaataacagg tgtgagtact gatgttacta gtgaagatgc
     9841 aagaaatata attgaggaat gtttagagac tatagataaa gatgcagatg tagaaatagc
     9901 attttttggt ggtagcttta ctgctataga tattgatata caaaaaagtt tattatcagt
     9961 tgctaaagaa tatgtagaaa aaggtcttgt aaaagatatt agaatgtcta caagaccaga
    10021 ttgtattgat gaagatatat taagtatgct aaaagaatat aagacaagta taattgaact
    10081 aggagtacaa tccttagatg aaaaagtatt attagatagt ataagaggtc atcaatctga
    10141 aattgtatac aagagttcaa agatgataaa aaatagtgga atcaaacttg gattacagat
    10201 gatgattggt cttccagctg acacagaaga aaagtgtata tttacagcaa aaaaatttgt
    10261 agagctaaaa ccagattgtg ttagagtcta tccaactttg gtagtaaaag atacaggtct
    10321 tgaaaagtta atggaacaaa ataaatataa tccatttact cttgaagaga gtgtaaatat
    10381 agtaaaaaaa gttcttgtac tgttttatgt taataatatc aatgtaataa gagttgggct
    10441 tcaagctact gatgatatac aaattggaaa agctgtttta gcaggaccat atcatcctgc
    10501 atttagagag ttggtagaag cagatatgat aaaagattat ttagaatttg ttattttgca
    10561 aaataaaaat ataaagcaaa tgttggtcaa atctaataaa aagaatattt ctaaaatcat
    10621 aggaaataaa aaaacaaatg ttaaatatat ggaagaaaaa tttggtgtgc ttttaaaaac
    10681 acaagaatcc gatttagata taaatcaatt agaaattgtg ttagatggga aaagtttaat
    10741 tagtgctaat atgagagaca ttcatagaaa attgtatgac atttatgacc tttagtttta
    10801 ataatgaagg gagagaaaag atttgtattt aaaaagacta gagttaaagg gatttaaatc
    10861 ctttccagta aaaacagata ttatttttaa agaaggaata acagccatag taggaccaaa
    10921 tgggagtgga aaaagtaata tatctgatgc tgtaagatgg gtattaggag aacagagtat
    10981 taagagtctt agaggtgata aactcgaaga tgtaatattt gcaggtacag atacaaaaaa
    11041 acctatgaat tattgtgaag tggctcttac tattgataat tctgaaaatc aattggaatt
    11101 agattttaca gaagtaacta taagaagaag ggcttataga aatggtgaaa gtgaattttt
    11161 tctaaataat aaaagttgta gattaaaaga tataaaagaa gtctttttag atactggtat
    11221 tggaaaagat ggttattcaa tcatagaaca aggaaaagta gatgaaatat taagtaataa
    11281 tcctttaagc agaagaaaag tttttgatga agcttgtggc atatcaaaat atagatataa
    11341 aaaacaggaa gcagaaagga atttaagtaa tacaaaggaa aatttagaaa gaatagatga
    11401 tgtatatata gaaattgaaa atcaattaaa gcctcttttt aatcaacaga caaaggcaaa
    11461 aaagtacttg gaaataagtg aaaaattaaa gatacttgaa gtaaatagct ttataagaga
    11521 aattgaagga atagaaaaag aattaagtga ggttaatgaa catcgtaagg ttattgaaaa
    11581 ggagctcaat gaaaaagaag aacaaaaaaa tgttgtagag aaaaagcaag aagatattaa
    11641 taaagaggta gaggtattac aagatgtaat tgaaaaatct gtagattata taaattcaat
    11701 taaaggagtt atatcaaaaa aagagtccca aataaattta attaaggaaa gaataagaaa
    11761 ttttacgaat gaaattagta gaaaaaattt agaaataaat gatataaaag agaagctaaa
    11821 tgaaaataag caatacataa aagaattaga aagtaataaa ttatcaggta gtgaagaact
    11881 atctaccttg caggaaaata taaaagtatt ggaggcaagt aaagataaac aaaaaattaa
    11941 gttagaatcc ctaaataatg agatagaatt attgaaagaa agtataattg atatattaaa
    12001 taagaaacaa gagtttagta ataagctgtc cactttaaac gcaaataaag aaaatatgaa
    12061 tatcagagat gaaaatataa attcagagat aacagagtta aacaaaaata ttgaaataaa
    12121 atcatctgaa ttagatacta taaataaaga atttaatatg caaaatgaaa atttaaagaa
    12181 tgtaaataat agacataaag aattatcaat taatttgcag gattcaatta gtgaacacaa
    12241 taaactagaa gatgaaatac agaaaagtaa atataattta aatggatata attcaaagtt
    12301 aaatgtctat atagatatgg aaaatcatta tgaaggattt aatagaggag taaaagaagt
    12361 actaaaaaat aaaaatttaa aaggagttca tggagcatta ggacaaatta taaatgtacc
    12421 tgaaaaatat gagaaatcta tagaagcagc tcttggtgct tatatgcaaa atataataac
    12481 tgataatgag tttagtgcta agtctgcaat aaactatcta aaacagaata atttaggtag
    12541 agtaacattt cttccattaa atataattaa atcaaataaa gtaagtctag gaaatttaaa
    12601 agcaaatact aagttcatag gaatagcaag tgatttaatt acatttgatg aaaagtatag
    12661 aaatataatt gaaaatatac ttggaagaac aatacttata aataatatag atgagggcat
    12721 aaaatttgca aaagaaactg gtcataggtt taaaatagta actttagatg gtgaaatctt
    12781 aaatccagga ggttctttga ctgggggaag tctaaaaact aatgggaata tactatcgag
    12841 aaaaagatac attaatgaat atacagaaaa gataagtaat atcaagaatg aaatttcaca
    12901 tctagaatta aaaagagaat ctttagacaa agatgtgaaa aatatcaaaa atgaaattga
    12961 ttcacatgaa agtaaaataa aagatttaga aaaaagtata ataataaaaa gtacaagtat
    13021 aaagaatgtt gaatctgaaa ttgaatcgtt aaaaggtagt attactaaat tagaaaatga
    13081 gaagaatgat ttaaattcta atctaaatta tacacttgaa aaaagcgatg atgttagaaa
    13141 agatatggaa gagttagatg atttatacaa taaaaataaa gaaaaaattg atgcattgaa
    13201 tgaggaaata aaaagataca atgatttata tgataaagaa aaatctgaat ttgatgaatt
    13261 gaacttaagt ttagtgaaga aaacagaagc ttataatagt atagttagag atataaaaag
    13321 aatatctggt gaaaattgtg agctagaaga aaagaataaa caattagaag agtcattaaa
    13381 ttatgaagaa catgaaataa ttaaattaca agattctata gccactgaag aaaaagaaaa
    13441 agaaaattta acaaaacaac taggggatag taatagaaat cttgaaacta gaaaaatagc
    13501 aaaagatgat ttaaaaaata gttttgatga aattaataaa gaattaaaaa ctatagatag
    13561 acagcatata gagcttaaag aaagtttatt taaagttggt ggaagattag aaagattaaa
    13621 aactagtcaa gacacatata taaataagtt gtttgagcaa tatgatatga ctttagtaca
    13681 agcattggaa attaaagatg aagatttgga tatagataga aaattcttag aaagtctaaa
    13741 gagagaaata agaagtcttg gaaatataaa tataggctct ataaaggaat atgaggaaat
    13801 aaaagaaaga tacgattttt atagcgaaca aaagcaagat ttagaagagt ctatggaaga
    13861 gatagaaaaa cttatacaca ctttagaaga aaatatgaaa tctgaatttg aaattaagtt
    13921 tgaagaaata agtaaaaatt ttaaatatgt atataagaga ttatttggtg gaggttgtgg
    13981 agaattaact attttagata aagaaaattt attagaaagt gatatactaa taacagctca
    14041 acctccaggg aaaaaaatga aaaatttaaa tctattatct ggtggagaga aagctttaac
    14101 agcaataagt atattatttg ctatattgat tacaaagcca acaccatttt gtatattaga
    14161 tgagattgaa gcgccacttg atgatgcaaa tatatttaga tttggagaat ttttgaagga
    14221 tttatctaaa gagactcaat ttatatcagt aactcatagg agaggaacta tggaagctgc
    14281 tgattatatc tatggagtta caatgcaaga aaaagccatt tcaaaagtta ttagcttaaa
    14341 attaaaagaa gctcaggaaa taacagatat tatataactt agattgacat aggaggaata
    14401 acagtgttaa aaaaattatt tggttttgga aaagacaagg aaaaagaaat agaaaaaaaa
    14461 gatgctgaag aagaaataga agttgaagac agtgttgata gtttagaaaa cttggaagaa
    14521 accatttttt caggacttga agaagaagtg atagataaag tggaagatat tgaagaaaaa
    14581 actgaggaaa gtgtcaataa tgaaggcact gaagaaatcg aaaattttga aaaaatagaa
    14641 gttgagatgg atagtaatgc aaaagaagta gaaaatattt caaataatga ttctcaagaa
    14701 gagataatcg aagaattaga aaattatgat gaaattgagt ctaaagagat agaagataaa
    14761 gaagataaga aagttaactt gtttgaaaga ctaaaacaag gattgacaaa agcaaagcaa
    14821 ggaataactg atagaataga tgaagtttta aaatcatata caaaaataga tgaagaatta
    14881 cttgaagatt tagaggaaat tttaataaca gcagatgttg gtgtaaatac aactatggat
    14941 ataattgaaa gactaagaga taaaataaag caaaaaggta ttactgaacc aataaaggta
    15001 agagaagaac ttaaatctat agttgaagat attcttacaa atgaaaactc tacactagat
    15061 atagaaccag caccatgtat aatattaatg gtgggtgtaa atggggtcgg taagactact
    15121 acaataggta aactagcaaa tagatacaaa aaagatggta aaaaagtttt attagcagca
    15181 gcagatacat ttagagcagc agcaacagag caattagaaa tttgggcaaa tagaaccaat
    15241 gtagacataa taaaacatca agagggagca gaccctggag ctgtagtatt tgatgctata
    15301 aaagctgcaa aagctagaaa aacagatgta ttaatatgtg atacagcagg aagattacac
    15361 aataaggcta atcttatgaa tgaacttgga aaagtattta aaatagtaga tagagaattt
    15421 ccagaagcaa aacgtgaagt acttcttgtg gtggatgcta caacaggtca aaatgcagtt
    15481 gttcaagcaa agacatttaa agaagttgca gatataacag gtatagtact tacaaaactt
    15541 gatggaactg caaaaggtgg agtagtcctt gcagtaaaat cagaagtaga tgtacctgta
    15601 aaacttattg gagttggaga aagtgtagaa gacctacaag atttcaatgc aaaatcattt
    15661 tcagatgcat tatttggtaa ctaatgttct tttaaaaata atggttgaca agagtgttgt
    15721 tatgatataa aatacaatag tgtaaagtaa ataaccttta cagtatactg ctaggaagtg
    15781 taagatatga atatagaaaa aatggtcgaa attggattgt tatttgaaca gtataaagaa
    15841 ttattaactg acaagcagaa agaaatagtt gctctatact atgaagaaga ttattcttta
    15901 ggtgaaatta gtgaaaatct gaatgtatca agacaaggtg tttatgatac cttaaagcgt
    15961 tcagaaaaaa tactaagaga ttatgaagaa aagttacact tagtatcaaa gattcaagag
    16021 caggaaaaaa atattaagat tataaaagat aaaattattg acattaaaga agatttattg
    16081 cacaatagag attgtgctaa tttaatccct aagctagaaa atatagaaga tgtatgtagg
    16141 gagatgataa aatgatattt gaaggattgt ctgataaact acaaggggca tttagtaagt
    16201 taaaatctaa aggaaaactt acagaagtag atgtaaaaaa tgctatgaga gaagttaaac
    16261 ttgctcttct tgaggcagat gttaacttta aagtagttaa agatttcata aaaaaagttc
    16321 aagagagatg tgttggacaa gaagttatgc aaagcttaac tccagctcag catgtaatca
    16381 aaattgtaaa tgaagagctt acaagtttaa tgggagatgt acaaagtaaa gtaatgattt
    16441 cctcaaagcc tcctacaatt ttaatgatgg ttggattgca aggtgcaggt aagactacta
    16501 cagcaggaaa acttggagga tattttaaaa agcaaggtaa aaaacctcta ttagtagctt
    16561 gtgatattta tagaccggca gctataaagc aacttcaagt tgttggagaa aaattggata
    16621 tacctgtatt caatatggga gataaagaaa atccagtaaa tattgcgaaa gcaggtttaa
    16681 gccatgcgat taaaaatgct aatgatttag ttattataga tacagctggt agacttcata
    16741 tagatgaagt acttatggct gagttaaagt ctattaaatc agaagttaag ccacatgaga
    16801 tacttttggt tgtagattct atgacaggtc aagatgctgt aaatgttgca gaaagcttca
    16861 atgaggcact tggtgttgat ggagtagtat taactaaatt ggatggagat actagaggtg
    16921 gtgctgcact ttcaataaga gcagttacac aaaagcctat aaaatttatg gggatgggag
    16981 aaaagctaga tgatatagaa cctttccacc cagatagaat ggcatcaaga atattaggta
    17041 tgggagatgt cttaagttta atagaaaaag cacaagaaaa tatagactta gagaaagcta
    17101 aagaattaga gcaaaaaatt aaaaaacaag agcttgattt tgaagatttc ttacaacaaa
    17161 tggaacaaat acaaaatatg ggacctcttg acaagatact tggtatgata cctggtatgg
    17221 gaaatgtaaa agaccaactt ggagatgtag atttgaatgg caaagaaatg aagagaacaa
    17281 aagccataat tcagtcaatg actacatatg agagaagaaa cccaggagta ttaaatgctt
    17341 caagaaagaa aagaatagct aagggcagtg gaactagtgt acaagatgta aatagactta
    17401 taaaacaact taatgaaatg aaaaaaatga tgaagatgtt tgctggttca caaaagagta
    17461 tgaagaaaag gggcggctta ggcggtttac ctttttttaa ataaaatata aaaaagtaaa
    17521 aattattcgg aggtgactgt aatggcagtt aaaataagat taaaaagaat gggagctaac
    17581 aaaaaacctt tctacagaat agtagtagct gattcaagag ctccaagaga tggaaaattt
    17641 atagaagaaa taggatacta taatccaatt tctgaaccta aacaagtaag aataaatgat
    17701 gaaaaagcta taaaatggtt agctactggt gctcagccaa cagaagtagt taaaaaatta
    17761 cttgtaaaaa acggagtaat agaaaaattc gaagcttcta aacaagcaaa ataatttttt
    17821 cttggcaatt agtttaagta agggctcatt gctaaggtta ctttaggaga tgaaatatat
    17881 gaaagagcta gttgtagata tagctaaggc tctagttgat aatcctgact cagttgttgt
    17941 tgaggaattt gaagataatg atggtatcgt cttaaagctt acagttgctc aagaggatat
    18001 gggtaaggtt attgggaagc agggaagaat agctaaagct ataagaactg tcgtaagatc
    18061 tgttgcaaat agagaaaata taaaagtttc tcttgagata gtataaaata ggaggattag
    18121 gtataatgcc tagtcctttt tatataaatg cgtagtttaa gattttatga tgatatgacc
    18181 acataagatt aaatttttta agaaggtgat aacatgaaag aaaaattaac tcattttaag
    18241 gtaggtcaaa tagtaaatac acaaggttta aaaggtgaag taagagttta tccacttact
    18301 gatgatatag agaggtttga tgaattaaaa gatttctatc tgggaaaaga tttaaataat
    18361 aaattggctg ttgaaaaagt aagatacaaa ggttctatgg ttataatgaa gataaaaggc
    18421 atagacagca tagagaaagc agaaaaacta aaaaataaat ttatgtatgt atctagagaa
    18481 gatagcagag agcttgaaga aggcgaattt tttatagcag atatgattgg aatggaagtt
    18541 ttaactgtag atggaaaata tgtaggaata ctagaagatg ttcttcaata ctcagcaaat
    18601 gatgtttatg tagtaaaagg tgaagaagat aaagaattta tgataccagc tataaaaaaa
    18661 tttgtaccta caatagatat tgatgaaaga aaaatgatta tagaccctat taagggaatg
    18721 atagattagg tggtaatatg agatttcata taatgacact ttttccagaa atatttaatt
    18781 cgtacatgga tgaaagtata atgaagagag cagttgaaaa aggtataatt gaggtttata
    18841 tatataatat aagggatttt tctaataata aacataaaaa agtagatgat tatccatttg
    18901 gaggaggagt ggggatggta atgactcctc aacctatata tgacacatat aagcatataa
    18961 taacaactca caatataagt aatccaagtg taatttatct tactccaaaa ggtaaggtat
    19021 acaatcaatc tatagcaaag cagatgtctt taaaagaaga tataatacta ttatgtggcc
    19081 attatgaagg agtagatgag agaatcattg atttaatagt tactgatgaa atttcaattg
    19141 gagattatgt attaactggg ggagagctcc cagcacttat aatgatagat tctatatcaa
    19201 gattaatacc aggtgtatta aaccaagaag aatcatttga agaagaatca tttaaagata
    19261 acttattgga atatcctcat tacactagac ctagagattt tgaaggatta aaagtaccag
    19321 aagtgctttt atcagggaat cataaaaaga tagatgagtg gagaagagaa gaatctataa
    19381 ggataaccaa agaaagacga tttgatttat ataaaaagtc taatgaaaaa taaaaatata
    19441 atgaaaaatt aatatatatg tatacaataa agtacctata aatggaatta aaaacataaa
    19501 agtgcttgta ataactattg aagtatagta taatataaaa tgttgaaaat acgggcgttc
    19561 ctctgtttac actggtcggg tagttaagaa cgtctatgat atctaggagg aagaaagatg
    19621 aatgaaatgc taagagcaat tgagcaagaa caattaaaaa atgaagttcc taattttgga
    19681 cctggggaca cagttaaagt acacgttaga attatagaag gaaaaagaga aagaatacaa
    19741 gtattcgaag gtgtagtatt aaagagacaa ggtggaggag caagagaaac tttcacagtt
    19801 agaaaaatgt ctttcaatgt tggtgtagaa agaactttcc cagttcactc tccaaaaata
    19861 gaaaaaatag aagttactag aaaaggtaaa gtaagaagag ctaaactaaa ctacttaaga
    19921 ggtagagtag gtaaagctgc taagataaaa gaagctagaa ataaataatt aaaaacttta
    19981 cttataaatg gggggctgat ttatcagtcc tctttctatt ttaatgaaaa ttacagcaaa
    20041 taattatact agaaataaat agaaatattt gttgaaaata tacattattt atctatgaat
    20101 ttatagcttt taaaatgaaa aataaaattg gtaaatattg gattatattt tgtaacgata
    20161 ttaaaaataa gagaacagta ttatgtaaag tatgacgtta aaaagatgac aatattatag
    20221 tttgtgaaga tagatttttt aagtggaatt agaatataat aatataatat taataaggag
    20281 tgatacatgt gtcaaatgaa tacgaagagt atcttatgga tgacaatcta catataaact
    20341 ggtatccagg tcatatgaaa aaaactaagg agttagtaaa aaataactta aaattgattg
    20401 atgtagtaat tgaacttttg gatgctagaa tcccgtttag tagtaaaaat ccagacatag
    20461 acaggcttgt aggagataag ccaagagttg tcgtacttaa taagagtgat atggcagata
    20521 gggataaatt gaatcaatgg attgaatact ataagaaaat taatatcaaa gctataccag
    20581 tagatacaat aaaaggtgtt ggtataaata atataatcga agaatgtaaa aatgtaacta
    20641 gagaaaaaat gagttcttta aaagacaaag ggagaaaaga aagagctata cgaataatga
    20701 tagttggagt tccaaacgtt ggtaaatcgt ctcttataaa caaattaaca ggtagaaaaa
    20761 gcactcaaac tggagataag ccaggagtaa cgaaagggaa acaatgggtt agattaaagg
    20821 gaaatcttga acttttagat acacctggaa tactttggcc taagtttgaa gaccaagaag
    20881 ttgcattaaa tttagcattt agtagagcta taaaggatga gattttagat actgagactt
    20941 tggctttaag acttatagaa aaacttatga aaatagaacc tgagaagttg aaagccagat
    21001 ataagttaga ttgtctagga gaaactccaa ttgaaactat ggatatgatt ggccataaaa
    21061 gagggtttat aacaggtaaa aaagaactag attatacacg catagccgca actgtattaa
    21121 atgaatttag agatggaaaa ataggaaata taacattgga agttccagaa aacgttaaaa
    21181 gatagatttt aaaacaaaat caaagattta atgttaaaaa aataaaaaag ccttttagca
    21241 aaggcttttt tatttttttg aaatatagac aaatatctcc atataaaagt ataaattagg
    21301 ttagaaaacc tttaaaaata ttaatttaag acaaatacac ctaatatttt gaaaattaaa
    21361 atgagtgtga ttattttaaa ttttagcata ttgacttgct tgtttcgtat aatatataat
    21421 aagcacaaat aaatacaata tattaaaaat ttaatttatt taattttatt aatttaataa
    21481 taagttctta ttgtttaatt taatttattt atgcaagcgt aaacaatcga gacattttat
    21541 taatttaata aggttaaaaa gggggatttt ataatgggta agaccaagga tgttatagta
    21601 tttggatttg cgttatttgc aatgttcttt ggagcaggta acttaatatt tccaccttac
    21661 ttgggaataa ttacaggtcc agaatggtta attgccttct taggatttac gtttgctgat
    21721 gctggattgg cacttctagc agtaatggct acagctaaat tcgatggaaa cgtagttgaa
    21781 atgtttaaaa gatgtggtat gaagttaggg attcttatag gttgtgcaga cattttatgt
    21841 ataggtccat tcttagctat accaagaaca ggtgcaacaa cttatgaaat gggtataatg
    21901 cctttatttg gaacttcaat tccagtgtta ttattctgta tacttttttt tgcgctttca
    21961 tatgtactaa caataagacc ttctaaggtc gtagatatag ttggacagtt tttaactcca
    22021 gctcttttaa tagctctagc atttataatt ataaaaggta ttatatcacc tcttggagat
    22081 atagtagata aacctatgat acctaatgta tttgcagaag gtataggtca aggatatcag
    22141 acaatggatg cttttgcagc aatagcactt gcatcagtgt taatagtatc tttaaatgat
    22201 aaaggatatt ctactattag tgacaagtta aaaatgattg gtaaggcggg ggttcttgct
    22261 tgtggaggat tagctctagt ttatggagga ttatgtttcc ttggagcaac tgtatcaaca
    22321 atgtatggaa cagatgcagt acaatcacaa gtaatagtaa atataactga aggattactt
    22381 ggaaatgttg ggaaagcgat tttagcagta gtagtatcat tagcatgttt aactacatct
    22441 ataggtctta catctgccac aggtcaatat ttctctagac ttacaaaagg taaattgagt
    22501 tatgaaaaaa tagtattagc tgtatctgta ttcagtgcag tagtagcatc ttttggtgtt
    22561 ggaactataa taaagatagc atctcctata ctaagtatag tttatccacc atcaattgtt
    22621 ttaataattt tagctttctt caatgaaaaa attaagaatg ataatgtgta caaaggagca
    22681 gtatatatgt cattgcttgt aagtatacta acagttatat ctagttatgg agtagatgtt
    22741 ccagtagtaa aatctttacc tcttcattca ttaggattta actgggtggt accagttata
    22801 atagctggaa taattggtaa ttttatacca tcaaagagtc aatctaatac acttggaaca
    22861 aactaagttt tgtttaatta aaatataatc aattgtaaat aaatgagtta actaaaagta
    22921 aaaggagtta tttgtacaaa taactccttt tattttggga ttct
//
LOCUS       DAMJYN010000058        22712 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.059, whole genome shotgun sequence.
ACCESSION   DAMJYN010000058 DAMJYN010000000
VERSION     DAMJYN010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22712)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22712)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22712
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.059"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            20..487
                     /locus_tag="PC466_002493"
     CDS             20..487
                     /locus_tag="PC466_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HDF2769861.1"
                     /translation="MITKFFSNILSVFLYFLLSLLGVAGIIFLCMIPMFLYDFSSDKV
                     IALIARILYFSDYFIVILFLIFIINSTKYSPFILENVKRFKVMGCCLLINTIIECVIG
                     YNSNTSLIMIFGDNSGGISPLMVISFIFALMCFVIAETFDKAIKIKEDNDLTI"
     gene            498..713
                     /locus_tag="PC466_002494"
     CDS             498..713
                     /locus_tag="PC466_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2769862.1"
                     /translation="MAIVVNLDVMMAKRKISLKDLAEKIDITNANLSILKTGKAKAIR
                     FTTLNEICKALDCQPGDILEYVEDEND"
     gene            1153..1326
                     /locus_tag="PC466_002495"
     CDS             1153..1326
                     /locus_tag="PC466_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase"
                     /protein_id="HDF2769863.1"
                     /translation="MKRKLSTYFKGYILGLCIAFLLFTFILKKLIIENIIGIIIGTGI
                     AFLLIYLFNKKRK"
     gene            complement(1483..1767)
                     /locus_tag="PC466_002496"
     CDS             complement(1483..1767)
                     /locus_tag="PC466_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769864.1"
                     /translation="MLVYNKSFYPNDIFPRLDFSKIKKQLKLIDNDLSDFGRICIIEK
                     EHYTISVNSIGEINVYYDLEYENKVYRIVYEIEKLFKSQVGRFSISTYRN"
     repeat_region   1879..2561
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=2004..2031
                     /rpt_unit_seq="tttacattccatatagttaatataaaac"
     gene            complement(3392..4264)
                     /locus_tag="PC466_002497"
     CDS             complement(3392..4264)
                     /locus_tag="PC466_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDF2769865.1"
                     /translation="MEETNEMKDSKHLISNIQSQYTRLSKGQKLIAQYILNNYDKVAF
                     MTACKLGETVGVSESTVVRFANALGYSGYPKLQAALQELIKNKLTTVQRVEMAHDYSD
                     DFAILNKVLKSDIDNIRSTLEEIDERAFKEASNKLLRARKIYILGMRSSFVVAQYLGF
                     YLDIILDNVHIIRMDMGDAFEQIVRINEEDVIVAISFPRYSKKSYQIVNYAKEKGAHV
                     ISLTDSLFAPVASLADNTLLVKSNMASFVDSLVPALSISNALAISVGMKEKEDIKQHF
                     DDLEQIWKRYSVYE"
     gene            complement(4658..5236)
                     /locus_tag="PC466_002498"
     CDS             complement(4658..5236)
                     /locus_tag="PC466_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HDF2769866.1"
                     /translation="MAYAKYLTKITDINKFYLENIINEGDIVIDATMGNGYDTRYLAE
                     KVGEKGFVYAFDIQEEAIKSTRKKLEKEGYTDRVKLIFDGHEKMNQYIKEEVSCVLFN
                     LGYLPRAKHSIITKPDTTLKAIKLSLEMLKENGVISIAIYTGHDGGQEEKDCIYNLVN
                     NLNQDEFNVLESKFLNQVNNPPQLILIEKKKA"
     gene            complement(5294..6010)
                     /locus_tag="PC466_002499"
     CDS             complement(5294..6010)
                     /locus_tag="PC466_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HDF2769867.1"
                     /translation="MRINKYIASCGIASRRKSEEIILGGRIKVNGSVVKELSFNIDEE
                     KDIVEFDNKKVKPSENYIYIVLNKPEGYITTVKDQFNRPSVIDILKDVRERVYPIGRL
                     DYETSGLLILTNDGDLTYKLTHPKHEIDKTYVASVKGIISDDEIRQFETGLKIEDYTT
                     APAKIRVTKENKEKNYSVCEITIHEGRNRQVRKMCKAINHPVLNLRRISVGKIVLKDT
                     KVGEYRYLTEDEIKYLKSIK"
     gene            6201..7286
                     /locus_tag="PC466_002500"
     CDS             6201..7286
                     /locus_tag="PC466_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HDF2769868.1"
                     /translation="MIIILKENIKYYLIVVFIGILFFKFINTPSNFISSIEGFLKFFS
                     PFLLAILLALLLNPLVMLFEVKFKAHRLLAIFLSYIFIGFILAFAIRLLIPSIANTLN
                     RLINEMPMYTDYIDSFIEKNMSNIDFLKTLIPHIQHSLDNLLKEASNFVGKIPKNFLI
                     YTLSISSMLFNMTMGFILSIYIIYDKEKIALGFKRFLYSSTARNKADNIIEFFRTTHD
                     IFYDYLLGRILDSLIIGIIAFLGFQFVIRIENALFLASIIFLGNIIPYFGPFIGAIPP
                     IAMTILYSPQKTIWVIAFLFILQQLDGNFIEPKVMGNQVGIGAIWVISAILVGQSLFG
                     FIGVFLSVPIAAVVKTYVDKYIDNRLQ"
     gene            complement(7441..8100)
                     /locus_tag="PC466_002501"
     CDS             complement(7441..8100)
                     /locus_tag="PC466_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769869.1"
                     /translation="MRGRVILLISILSIFLVGCSFNKKDEINLVEQGKTYLEKHNYKK
                     AMESLSSALEEDSTNENARAMYMQAMRMSNMTEFEELKNYEGAIKELKLIEKIKNGSS
                     VIKEEATKKKEELTKLEKEQNEAEEQRKKKAKDTAGEDRYRVESDARKSSYSGSSKNN
                     KYSSKNNDKKSDSNKSDNNNSSSQNQEKPNNSNPTPAPTPQDTTGGSDSGGNSQNSNN
                     Q"
     gene            complement(8317..9609)
                     /gene="lysA"
                     /locus_tag="PC466_002502"
     CDS             complement(8317..9609)
                     /gene="lysA"
                     /locus_tag="PC466_002502"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HDF2769870.1"
                     /translation="MKLHGTMTVNNDELYIGGVSCLELSKKYQTPLYVFDEALVRQNC
                     REYIEYFKAREGKNKVAYAGKAFLPLYMCNLINEEQMCLDVVSGGELYTAYKSNFPME
                     KVFFHGNNKTKEEINMGLDLGVGKFVVDNFYELDLLEALCEDKGKTQEIYFRITPGIE
                     AHTHDYIKTGQIDSKFGFALVNGDLFRAIEKLSEYKNIKLVGLHAHIGSQIFDVEPYI
                     DTVDIMMNLVKEIKEKFNIQLTEIDLGGGVGVYYSEGDKPKTIKEFCETIITKAETSC
                     KELGIEVPTLVIEPGRSIVANAGSTLYTVGSIKDIKDVRVYVSVDGGMTDNVRPSLYQ
                     ASYECSIVNKINHEAMNHVTIAGKCCESGDILIGDINIMDIKSGDILITTSTGAYGYS
                     MSSNYNKIPRAAVVSVFDGNDKIICKRQSYEDLLALEI"
     gene            complement(9627..10820)
                     /locus_tag="PC466_002503"
     CDS             complement(9627..10820)
                     /locus_tag="PC466_002503"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HDF2769871.1"
                     /translation="MSIIVQKYGGSSVADTEKIKSIAENIIERRKENPQMVIVVSAMG
                     KSTDEYITLAKELSNEPSKRELDALMSTGEMISASLLSIALNALGCKAISYNAYQLNI
                     KTSGLHGKSQIDDINVNRIKNSLDEGNVVIVTGFQGINEDGDVTTLGRGGSDTSAVAL
                     AVKLNGKCEIYTDVDGIYFTDPRKYSKASKLDEIEYEEMLELASLGAQVMHSRSIELA
                     QKYGVEIYVGRTCGTEKGTYIRGGKDMKLEDKVITGLATSDDDSSITIKDFKAENISS
                     LFEDIATIGISVDMISQTAPILDKISVSFTVPKEELGECKKIVSKYTDEEHVVIDNNI
                     TKFSLVGLGMKNTSGVAAKVFKIFNENGIMIKLITTSEIRITCAINSDDKQVAIEKIA
                     EVFNI"
     gene            complement(11181..11798)
                     /locus_tag="PC466_002504"
     CDS             complement(11181..11798)
                     /locus_tag="PC466_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769872.1"
                     /translation="MTNMEKEILLLISRVRCVTESQFRKIYGDQKRYNKKNFKKTLRK
                     MCSEYTLKKYPCDVDYYNYKDLSYVYYLNGSKLFKGDDLIKALVGSELVVRINTAGCD
                     VKRFYRNVSVDDVKYDLFIEYTDQFGNIKQVLVDVDLNNEIDISKYENLSKKIDKSTI
                     PFFKVPNVLVVTPDNLSELNDLERYDNEYSINFIDLGLNKLFNCI"
     gene            complement(11968..13668)
                     /locus_tag="PC466_002505"
     CDS             complement(11968..13668)
                     /locus_tag="PC466_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769873.1"
                     /translation="MKRYLKTYGVALIIVIIYAFIKLPVLRLDFTSLFSVGIIFFVVA
                     GILDMMLDRNERASKMAKYNFSIAIALLVYIVVVPFITSTPVLHAKSYRELLGKVTES
                     KFTDDISPVSVNDIRLVDEDMAMKLGDKKLGEVPAIGSVSKLGKFHIQNVDGELYWVA
                     PLVHRDIIKWITSLSGTSGYVKVSASNPQDVQLVQEIDGKPIKIVYQPEAYLHQDLQR
                     HLYIHGIVNVGMTDFTLEINDEGRPYWVVSLYEHKIGYGGANATGIATVDAETGKINV
                     YDVKNTPKWVDRIQPQSFVTDQIKDWGVYVNGFLNSVISEKGVLVPTEGTSLVYGNDN
                     RSYWYTGITSSGGDESTIGFMLVDSRTKEARLYKQPGATETAAMKSAEGNVQEKNYEA
                     TFPVMYNILGQPTYVSSLKDKAGLVKRVAFVSVEDYNVLGIGEDKNEALRNYKDALES
                     KGNDLKLDNDLKDEVLEGTVTRISPDVRGGNTNYYVTLDSNKDIIFRATSKVSSELPL
                     TQVGDKVKISYSKEESGVIEMSEFDNLNIANFEDKKAKEKTGTDENTDSKDSENQGNV
                     "
     gene            complement(14065..14628)
                     /locus_tag="PC466_002506"
     CDS             complement(14065..14628)
                     /locus_tag="PC466_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769874.1"
                     /translation="MNKVYIVTTYTGTILSYLIRNISKKLYTHVSISLNENLKPMYSF
                     GRLNPRNPFIGGFVEENINQGLYAIRKNTVCRVYSLEVDNLQYENLYKNIKLISDYRE
                     DYYYDTMALIYLLMNIQRQSEYKYVCSNFVADMLEKSEIDILNKQAFEVTPNDFYNLS
                     GLTLEYEGLLSEYNSRQHSYVSKIANI"
     gene            complement(14787..15500)
                     /locus_tag="PC466_002507"
     CDS             complement(14787..15500)
                     /locus_tag="PC466_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2140 domain-containing protein"
                     /protein_id="HDF2769875.1"
                     /translation="MGKVAKILLSLIVIVLVLAGIVVYILTPKERYDVSSQNNKIIDE
                     EYLSKGSYINSMEVVKNPLRMVGKISVSEEEFKNLIYTLMQKHGINELENNFVEMKNG
                     KIKVAGPYKVFGLVNSQYELELRPTLKDGNLVVSLENVKIGKFKLSDKMLEKILSNYN
                     KKVPFEVNGNKITLEKSYLYPITLKNISIKKGNVDLDMEVEIDLKSQINGALGYLKDS
                     GKVQDILNHLINLKKTSVG"
     gene            15792..17456
                     /locus_tag="PC466_002508"
     CDS             15792..17456
                     /locus_tag="PC466_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--tRNA ligase/YqeY domain fusion
                     protein"
                     /protein_id="HDF2769876.1"
                     /translation="MSNETNSSNFIKNIIINDLETGKHDSIITRFPPEPNGYLHIGHA
                     KSICLNFGLAKEFNGKANLRFDDTNPLKEDVEYVESIKEDVKWLGFDWNELNFASNYF
                     DEMYKRALILIKKGKAYVCDLTQEEMREYRGTLTEPGKESPHRNRTIEENLDLFERMK
                     NGEFKDGEKTLRAKIDMSSPNINLRDPIIYRISHSTHHNTGDKWCIYPMYAFAHPIED
                     AIEGITHSICTLEFEDQRPLYDWFVKECEMENIPRQIEFARLNINNTVMSKRKLKQLV
                     DEGIVDGWDDPRVPTISGIRRKGYTAEALRNFCSEIGVSKVNSTVDSQMLDYFLRENL
                     QPKAPLTMGVLRPLKLIITNYPEDKIEMLEIENNAKDESQGKRLVPFSRELYIEQDDF
                     MEEPVKKYFRFFPGNEVRLKGAYFVKCTDVIKDENGNVVEIHGTYDPETKSGSGFTGR
                     KVKSTIHWVDAKSAIPCEFRLFEPLILDDIPENEGKHFLEQINPNSLEILQGFVEPTQ
                     IKDSKPFDKFQFVRNGFFSIDNKYTTDEKFVFNRIVPLKSSFKPGK"
     gene            complement(17563..18462)
                     /locus_tag="PC466_002509"
     CDS             complement(17563..18462)
                     /locus_tag="PC466_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegS/Rv2252/BmrU family lipid kinase"
                     /protein_id="HDF2769877.1"
                     /translation="MKKVKLIYNPNSGEKKILSNLDTIIELYQEKNYLLIPYRLTIKE
                     PVKNAFKEVDSSYEHILIAGGDGTVDLVVNAMKELDIKIPIGILPTGTANDFSNALQI
                     SFDIKEAINEIINSKPKKIDIGKVNNKYFINVASAGMFTDVSQRINTDLKNSFGRISY
                     YIKGIEEALYMRKFKIKVSSEEMYYDGDMYLMLIFNGKTAGNINLAYKAEIDDGYLDV
                     IIFKGMPIPKSIPVLISVLRGDYLDQYNGNEILYFKTKKVHIECEDSLITDIDGEKGP
                     DFPLNIECIKDGIEVMGICSEKS"
     gene            complement(18489..19127)
                     /locus_tag="PC466_002510"
     CDS             complement(18489..19127)
                     /locus_tag="PC466_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003356606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate utilization protein"
                     /protein_id="HDF2769878.1"
                     /translation="MDQNLNWLNEKRIEKTIKSLENNNMKGYLVSNKEELLKKIEEIV
                     KVGSLVGCGGSMTLFETGVIDFIREKYNFLDRYAKDIKPEEMKEIYRKSFSADAYFTS
                     TNAITEDGELYNLDGNGNRVAAMIYGPDKVIVIAGVNKIVKDVDEAIKRTKTIAAPAN
                     CKRLSTNTGCKTTGICIDCSSPGRICCSYTLIKRQLTPERIHVIFLNEDFGY"
     gene            complement(19464..20462)
                     /locus_tag="PC466_002511"
     CDS             complement(19464..20462)
                     /locus_tag="PC466_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4003 domain-containing protein"
                     /protein_id="HDF2769879.1"
                     /translation="MEQSFINGKVNLLIENYKALNEVKGSWQMGLIQHSCALAFTLKN
                     KRISPRLVEERIELIKKNTGLFSNFRGYNMFYMATLLSFESNPESSFKMILDIYKELK
                     SEKFWGDTYLPLTASIVYENREKMDYLTCISKMKIIYDYMRKKHPFLTSSDDYCNIAL
                     IAIHSKNLDEDLEYIEKCYEFLNENGFYKGNDLQALSQILLFSDDRTMLKCKKTIELK
                     KAFKENDCKMNYYGYPIIGAISLLDYREDEIIEEIKNVSNKLKEEKGFGNWSLGKSNR
                     VMISSAIVASIYADLIRNENNIGSITNNIFLNIVVAIQIACVMAATSAAIASSSSN"
     gene            complement(20560..21135)
                     /locus_tag="PC466_002512"
     CDS             complement(20560..21135)
                     /locus_tag="PC466_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769880.1"
                     /translation="MKLKEALITCVVCSVCLTPLLVNGETKIDADHCKESIVNIDTIV
                     KSGKSFNSKYNQGMEDYKNSDEYKLKVQKEKLQNQLGIKIKKLVPITFEVSYYTSLNQ
                     ENGYGAITATGDDLEDGFVANNHLSFGTKIIVDGKLKTVMDRGSSKYFSNSNAIDVFV
                     PKWSNESESEYYDRVNNMGRHYKKGYIIVEE"
     gene            21451..21714
                     /locus_tag="PC466_002513"
     CDS             21451..21714
                     /locus_tag="PC466_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769881.1"
                     /translation="MIKNTKQITVEVNEILLQEISKITNDENNILTDLINESIVNYIL
                     ENKKHNIENKDLEEVIKFYKKENTEKPKSAARAIAEAKTHTLY"
     gene            complement(22143..22520)
                     /locus_tag="PC466_002514"
     CDS             complement(22143..22520)
                     /locus_tag="PC466_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF2769882.1"
                     /translation="MTITKIPPAELKVMKFIWSSDFTVASKDVIEAMEKLYNWKQTTT
                     LTLLSRLVNKQFLSARKIDRHTHYTVLIGEEEYLHFETKTFLDNMHGSSIESFMKSLF
                     KKGVNEEELNSVEKWVKDIKKDE"
BASE COUNT         7595 a         3656 c         2339 g         9122 t
ORIGIN      
        1 ataaaggaga tgatatttta tgattacaaa attttttagt aatatattat cagtatttct
       61 atattttcta ttatcacttt taggagttgc tggtataata ttcttatgta tgatacctat
      121 gtttttatat gattttagtt ctgacaaagt aatcgcttta attgcaagaa tactatattt
      181 ttctgactac tttatagtca tcttattctt gatatttata attaatagta ctaagtattc
      241 cccattcata cttgaaaatg taaaaaggtt taaagtaatg ggatgttgtt tattgataaa
      301 cactataatt gaatgtgtaa ttggttataa ctcaaatact agtcttataa tgatatttgg
      361 agataatagt ggcggtatct caccacttat ggttatttct tttatatttg cactaatgtg
      421 ctttgtaatt gcagaaacat ttgataaagc tataaaaata aaagaagata atgatttaac
      481 gatatagagg tgatgttatg gcaatagtag ttaacctaga tgtaatgatg gcaaaaagga
      541 aaatatcact taaagatttg gcagaaaaaa tagatattac aaatgcaaat ttatcaattt
      601 taaaaactgg aaaagcaaaa gctattagat ttaccactct aaacgaaatt tgcaaagctt
      661 tagactgtca gccaggtgat atacttgaat atgtagaaga tgaaaatgat taaaaaagag
      721 tgtttagaaa cactcttttt tattatacta tatgattttt attcttttac tatattattg
      781 acattaatat taactttgtt taaagtcata acaaaatacg ttctaagaaa gaaactgttc
      841 ctttttctat ttgttatcca ttacctataa gaactgtatc acactaaatc atacttttaa
      901 attgataatt ttgccacaga ttcctatata cattcttttc tacctaatat ttatttaaac
      961 tgttagcaaa acatggaact ttttcattta cttatacctc catttatatt attgcatagt
     1021 ttatagctac gtgttataaa ttacattatt gatgatttat ctaacatttg taatctttta
     1081 gatactcttt gaagttacaa cactgttata ctctaattaa gtaaactaaa tctgatacaa
     1141 gttggtgatt atatgaaaag aaaactttca acctatttta aaggatatat tttaggttta
     1201 tgtatagcat ttttattatt tacttttata ttaaaaaaat taattataga aaatatcatt
     1261 ggaataataa ttggaactgg aattgcattt ttactgattt acctatttaa taaaaaaaga
     1321 aaataatatt ctataaaaag gtcttttagt gaatttacaa aaaattaata agaataatat
     1381 atacttagta tttaaaaagg gtaacaactc tctctagctg ttaccttata tatttatcta
     1441 tatctttagt attaagtttt ttaatttcta cttttttaat tatcaatttc tgtatgtaga
     1501 tatactaaac cttccaactt gagatttaaa taacttttca atctcataaa ctattctata
     1561 caccttattt tcgtactcta aatcataata cacatttatt tcacctatac tgtttacact
     1621 tatcgtataa tgttcttttt ctattataca tattcttcca aaatctgaca ggtcattatc
     1681 tatcaatttt aactgttttt ttatttttga aaaatctaat cttggaaata tgtcattagg
     1741 ataaaaactt ttattatata caagcatttc atccacccct tatttattct atttatatca
     1801 ttttataccc taattaataa tttattaatc atctttttcc atattattca aattctctta
     1861 tataaaaaca aaatcaattt agaatatgta ttattaaata taaagtgact caatctttat
     1921 ttaataagaa aaaacattta tattacatat aattaatata aaactaatga agtgggtgta
     1981 tgaaagagaa aacacaattt taatttacat tccatatagt taatataaaa cagttgtttt
     2041 tattttttct aaagagaaaa aactagactt tacattccat atagttaata taaaactttc
     2101 tgtatatttt agttgtgttt taatattata acactttaca ttccatatag ttaatataaa
     2161 acatggcagt aactaagaag aaaactatac cttttttatt ctttacattc catatagtta
     2221 atataaaacg aggaaatttt atactaatga ctgatgctag atttaacttt acattccata
     2281 tagttaatat aaaactatta taaggagcat tatacgacca aaagccaaag cagctttaca
     2341 ttccatatag ttaatataaa acaagcaaca gcaagagtcg cgacaacatt aaaaacttcc
     2401 tttacattcc atatagttaa tataaaacct ttattttttt ctctatatcg agttcgccaa
     2461 attcactctt tacattccat atagttaata taaaacagtc cagcgttgtg tggtcgtaac
     2521 acaccaatcc tactttacat tccatatagt taatataaaa ccccaaaata aattaagtat
     2581 ttccaatact tatacatata caattctcct aaacttgcag tgagcgagca atagtgcaat
     2641 tgataacagt tatcatacac tctcaacgct ttatatttca actattaaac cctactttat
     2701 cacaaaaatc gctcactgca aaacttttat atttttatta tatcataaaa ctcatactat
     2761 aaaataaaaa tgggataatt ttacaaacta aaagcatcta cattcttata agtatttatt
     2821 atattctcta ttccaatgat tcctttttct ttttattgca tccttcctat gtaatcgcac
     2881 tttagctcaa caagtctttt attttcatta acaatttttt aaactattca aaatcatcaa
     2941 atttttcatc ttatacagtt aaatcaaaat acgtgttata tctctttatc tatatacttt
     3001 tcttccttcc atttcttttt ctctttctac attttcactt tgttacttta caatctcaag
     3061 gttattatct gctattaaag ttttatcttt ccaggtttca caaaaataaa ttgaataagt
     3121 gcaaaaataa cagatacaaa accataacta ttttcttttc tataaaaaaa tatatcatca
     3181 acaagaaaca taataaatga aaataactat gaataaatac tctcatttag aagaaataga
     3241 caaagatatt ccttaaaatt taagcaaaat attgtttaaa taaaaaaact gactgtcagt
     3301 taaatgccag tcagctattt tatatatttt atccaaacat cactatattt gaacatttta
     3361 ataattaata atacttatta atatacaaac tttactcata cacagaatat cttttccaaa
     3421 tttgctctaa atcatcaaaa tgctgtttaa tatcttcttt ttccttcatt ccaacagata
     3481 tagcaagggc atttgaaata ctaagagctg gaactagaga atctacaaat gaagccatat
     3541 tactcttaac tagaagagtg ttatctgcaa gtgatgctac tggcgcaaat aagctatctg
     3601 ttaatgatat tacatgggct cctttttctt tagcataatt gacaatttga taagatttct
     3661 tagaataacg agggaaacta atagcaacta ttacatcttc ttcatttatt cttacaatct
     3721 gctcaaaagc atctcccata tccattctaa ttatatgaac attgtcaagt attatatcta
     3781 agtaaaaacc taaatattga gctactacaa aagaactcct cattccaagt atatatattt
     3841 ttctcgctct taaaagtttg ttagaagctt ctttaaacgc tctctcgtca atttcttcta
     3901 gtgtagacct tatattatct atatcacttt ttaaaacttt gtttagtatt gcaaaatcat
     3961 cggaataatc atgtgccatt tcaactcttt gtactgtagt tagtttattt tttatgagtt
     4021 cttgaagtgc agcttgtaat ttaggatatc cactataacc taatgcattt gcaaatctta
     4081 caactgtaga ctcacttact cctacggttt cacccaattt acatgcagtc ataaatgcaa
     4141 ctttatcata attatttaaa atgtattgtg ctataagttt ttgaccctta ctcaatctcg
     4201 tatattgaga ttgtatattt gatatcaaat gtttactgtc cttcatttca tttgtttctt
     4261 ccattttttt ctccttttag ttatataaac tattttgttt tattaacact gtctttttct
     4321 ctaaaaattt tattttttat ctcaatttca tcttagtttt tatcatagct tcttaaactc
     4381 ataaaattct aacttttctg taccttatac ttcacatagt attttcgatt aaatttatta
     4441 taccatcttt ccttgcattt tttaatattt atccaatatt tcttttaaat ttttcaattt
     4501 ttactcattt aaaagttatc tatcttattt tgcatattta gatgtatatt ttgttttgag
     4561 aataagctgt tgtatactta ttatttaaag tatttttaat aggtcacact atatatatta
     4621 actcttaata gaatcttgtc aagtttttta gtatttatta tgcttttttc ttttcaatta
     4681 aaatcaattg tggtgggtta ttgacttgat ttaaaaactt agattctaaa acattaaatt
     4741 catcttgatt taaattattg acaaggttat atatgcaatc tttttcttct tgacctccat
     4801 catgccctgt atatatggca atgcttatta ctccattttc ttttaacatt tctaaactta
     4861 actttatagc ctttaaagtt gtatctggtt tggttataat tgaatgtttc gctcttggaa
     4921 gataacccaa attaaataaa acacatgaaa cttcttcttt tatatattga ttcatttttt
     4981 catgcccatc aaatatcaac tttactctat ctgtatatcc ttctttctct agtttctttc
     5041 ttgtagactt tattgcttct tcttgtatat caaaagcata tacaaagccc ttttctccaa
     5101 ccttctcagc tagatacctt gtatcatacc catttcccat agtagcatca attactatgt
     5161 ccccttcatt tataatattt tctaaataaa atttatttat atctgtaatt ttagttaaat
     5221 actttgcata tgccataata ctatttctcc ctactattaa ctttatttca ttttttctca
     5281 atttattttt atcttatttt attgatttta aatattttat ttcatcttct gttaggtatc
     5341 tatattctcc aactttggtg tcttttaata ctattttccc cacagaaatc cttcttaaat
     5401 ttaaaactgg atgatttata gctttgcaca tttttcttac ttgtctattt ctaccctcat
     5461 gtatagttat ttcacacact gaataatttt tttctttatt ttctttagtt acccttattt
     5521 tggcaggtgc cgttgtgtaa tcttctattt ttagtcctgt ttcgaattgt cttatctcat
     5581 catcacttat aattcccttc acacttgcca catacgtttt atcaatttca tgctttggat
     5641 gggtaagctt atatgttaaa tcgccatcat tagtaagtat taataaacca ctagtttcat
     5701 aatctaatct ccctattgga tatactcttt cccttacatc tttaagtatg tctattacac
     5761 tgggtctatt gaattggtct tttactgtag ttatatatcc ctctggttta tttaatacta
     5821 tatatatata attttcactt ggttttactt ttttattatc aaattctact atgtcttttt
     5881 cttcatcaat attaaaagat aactctttta ctacacttcc atttaccttt attcttcctc
     5941 caagaattat ttcttctgat tttcttcttg atgctattcc acaagaagct atatacttat
     6001 taattctcat acttaatcct tccttatctt aaattatgtg tgtttaatat ttttatcaat
     6061 gttaattttg ctacattatt atactatact agaccttaat taaaaacaag caaaaaaatt
     6121 atttaatttt cctaaataat tgtaatttct tttcacatac tattaatatg taatagctga
     6181 ctaaacacta ttttaaggaa gtgattatta ttttaaagga aaatataaaa tattatttaa
     6241 tagtcgtgtt tattggaatt ttatttttta aatttattaa tactccatca aactttatat
     6301 ctagtattga aggattctta aagtttttta gcccattttt attagctatt ttacttgctt
     6361 tacttttaaa tccacttgtg atgctttttg aggtaaaatt caaagcacat agacttttag
     6421 ccattttttt atcttatata tttataggtt ttattttagc ctttgccatt aggctattaa
     6481 ttccatcaat agctaataca ttaaatagat tgataaatga aatgcctatg tatactgatt
     6541 atatagatag ttttatagaa aaaaatatgt caaacataga ttttctaaaa actttaattc
     6601 ctcatataca acatagttta gataatttat taaaagaagc aagtaatttt gttggtaaaa
     6661 ttcctaaaaa cttcttaatc tatacactta gtatatcttc tatgctattt aatatgacaa
     6721 tgggatttat actatccata tacattatat atgacaaaga aaaaattgca ttgggattta
     6781 agagatttct atattcttct actgctagaa acaaggcaga taacattata gaatttttta
     6841 ggactactca tgatattttc tatgattatt tacttggtag aatattagac tctcttatta
     6901 ttggtataat tgcattttta ggatttcaat ttgttatcag aatagaaaat gctttatttt
     6961 tagcttcaat aatattctta ggtaatataa ttccctattt tggtcctttt attggtgcaa
     7021 tccctccaat agccatgact atattatata gtccacaaaa aactatatgg gtcattgcat
     7081 ttctatttat attgcaacaa ttagatggaa attttataga accaaaagtt atgggtaatc
     7141 aagttggtat aggagctata tgggtaatat ctgctatttt ggtgggacaa tctctatttg
     7201 gtttcatagg agtttttctt tcagtaccaa tagctgctgt tgtaaaaact tatgttgata
     7261 aatatataga taatcgttta caatagctta tctctactgt gactttaatt tttagtttaa
     7321 aatttaactg ttatttatta aattatttct caaaaaatat ctcttagtaa gaaaaaattg
     7381 ctaagagata ttttttataa tatataattt gttcattaaa tttatgcata tattttatac
     7441 ttattgatta tttgagtttt gagaatttcc accactatct gaaccaccag tagtatcttg
     7501 tggagttggt gctggtgttg gattactatt atttggcttt tcttgatttt gagaagaact
     7561 gttattattg tcagacttat tactatctga ttttttatca ttatttttag aactatattt
     7621 attattttta ctacttccac tataagaaga tttccttgca tctgattcaa ctctatacct
     7681 atcttctcca gccgtatctt ttgccttttt ctttctttgt tcctctgctt cgttttgttc
     7741 tttttctaat ttagttaact cttctttctt tttagttgcc tcttctttaa taacagagga
     7801 accatttttg attttctcta taagtttaag ttccttgatt gcaccctcat aattttttaa
     7861 ttcttcaaac tccgtcatat ttgacattct catagcttgc atatacatag ctcttgcatt
     7921 ctcattagta ctatcttctt ccagtgcaga ggataatgat tccatagctt ttttatagtt
     7981 atgtttttct aaatatgttt ttccttgctc tactaaattt atttcatctt ttttattaaa
     8041 tgaacatcct acaagaaata tagataatat cgatattaat aaaattactc ttcctctcat
     8101 taaatccctc cttgtcatat actttaaatt ttatcataat tataaagttt ttaaaatatt
     8161 ttatatttat tacaagaaat ttgttagtaa aacaaaaaat aagcagatat gctacgaacg
     8221 atacaataaa ccaaaaatta atttagagat acatatccta gcaaatctgc tcataataaa
     8281 ctttaatatt taatttttat tatatacttt tccattttat atctctaaag ctaataagtc
     8341 ctcatagctt tgtctcttac aaattatctt atcatttcca tcaaatactg atactactgc
     8401 tgctcttggt attttattat aatttgaaga cattgaatat ccatatgcac cagttgatgt
     8461 tgttataagt atatctccac ttttaatatc cattatgttt atatctccaa ttaatatatc
     8521 tccactctca caacattttc cagctattgt tacatgattc atagcctcat gattaatttt
     8581 attcacaata ctacactcat aactagcttg gtacaacgaa ggtcttacat tatctgtcat
     8641 acctccatct acacttacat aaaccctaac atcttttata tcttttatag aacctactgt
     8701 atacaatgta cttcctgcat ttgcaactat tgatcttcct ggttctatta ccaatgtagg
     8761 tacttctatt ccaagctctt tacatgaagt ttctgcttta gtgattatgg tttcacaaaa
     8821 ctcttttata gttttaggtt tatctccttc gctataataa acgccaactc ctccacctaa
     8881 gtcaatttct gttagttgta tgttgaattt ttcttttatt tcttttacca agttcatcat
     8941 tatatccact gtatctatgt atggttctac atcaaatatt tgtgaaccta tatgagcgtg
     9001 aagacctaca agtttaatat ttttatattc acttaatttt tctattgctc taaataaatc
     9061 tccatttact aaagcaaatc caaatttaga atctatctgt ccagttttta tataatcatg
     9121 tgtatgagct tctataccag gagttattct aaagtatatc tcttgagttt tacctttatc
     9181 ttcacataat gcttcaagca aatctaattc ataaaaatta tccactacaa atttacctac
     9241 acctaaatct aatcccatgt ttatttcttc tttagtctta ttgtttccat gaaagaaaac
     9301 tttttccata ggaaaatttg atttataagc tgtatataac tcgcctcctg aaactacatc
     9361 taaacacatt tgttcttcat ttataagatt acacatgtaa agaggtaaaa aagctttccc
     9421 tgcataagca accttatttt ttccctctct agccttaaaa tattctatat attctctaca
     9481 attttgtcta actaaagctt catcaaatac ataaagtgga gtttgatatt ttttactaag
     9541 ttctaaacaa ctcactcctc caatatataa ttcatcatta tttacagtca tagttccatg
     9601 aagtttcata atagcctccc caaattttat atattaaata cttctgctat tttttctata
     9661 gctacttgct tatcatcaga atttatagca caagttatac gaatctctga tgtagttata
     9721 agttttatca ttataccatt ttcattgaat atcttaaata ctttagcagc aactccagaa
     9781 gtatttttca taccaagacc tactaaagaa aatttagtga tattattatc aatcactaca
     9841 tgttcttcat ctgtatattt agatactatc tttttacatt ctcccaactc ttcttttgga
     9901 actgtaaatg atacacttat cttatctaaa ataggtgcag tttggcttat catatctaca
     9961 cttataccta tagttgctat atcttcaaat aagctagata tattttcagc tttaaaatct
    10021 tttattgtta tagaactgtc atcatcacta gtagctaatc ctgttattac tttatcctct
    10081 aatttcatgt cttttccccc tcttatatat gttccttttt ctgtaccaca tgtacgtccg
    10141 acatagattt caacaccata tttttgtgca agctctatac ttcttgaatg cattacttgt
    10201 gctcctaaac tcgctaactc aagcatttct tcatattcaa tctcatcaag tttactagcc
    10261 tttgaatatt ttcttgggtc tgtaaaataa attccatcaa catctgtata tatctcacat
    10321 tttccattta atttaaccgc aagagctaca gcagacgtat ctgaaccacc tcttccaaga
    10381 gtggttacat caccatcttc gttgattccc tgaaatccag ttactatcac gacatttcct
    10441 tcatctaaac tatttttaat tctgtttacg tttatatcat caatttgaga ctttccatga
    10501 agaccactcg tttttatatt taactgataa gcattataac ttatagcttt acatccaagt
    10561 gcatttaatg ctattgataa taaagatgct gaaatcattt caccagtaga cattaaagca
    10621 tctaattccc tcttactagg ttcattactc aattcctttg ctaaagttat atattcatca
    10681 gtggattttc ccatggcaga cacaactatt accatttgtg gattttcttt tcttcgttct
    10741 attatatttt ctgctattga ttttattttt tcagtatctg ctactgaact tccaccatat
    10801 ttttgaacaa ttatactcat gctttctccc cctcaagcta aattttgata aataaaaacg
    10861 cccaaaggta tactttggac gtgtaaattt catagaccaa gtaaccttgt agctcaccac
    10921 tttaaaagtg acagccttat gcatattctg cataagtcca gaaaatttgt ccgtcaacaa
    10981 aatttcttcg gctatatacc ctttcatcaa ttatcaatgc ttaccagctc ctattgaata
    11041 ctattgaata cagctacctc taccctaggc tcattatttt taattaattt attaatatag
    11101 ttttatcata ttctatataa tattgcaaca attattttac aaaatgtggc aaatcgatag
    11161 ttttcttttc taaagttagc ttatatacaa ttaaatagtt tatttaatcc taaatctata
    11221 aaatttatgc tatactcatt atcatatctc tctaaatcat ttaattcgga tagattatct
    11281 ggtgtaacta ccaaaacgtt tggtacttta aaaaatggaa ttgtagattt atctattttt
    11341 ttagaaagat tttcgtattt agaaatgtct atttcattat ttaagtcaac atcaactaaa
    11401 acttgcttta tattaccaaa ttggtctgta tattcaataa ataaatcgta tttcacatca
    11461 tctacactaa catttcggta aaatcttttt acatcacaac ctgcagtatt gattctaaca
    11521 actaattctg atcctactag agcctttatt aaatcatctc ccttaaaaag tttactaccg
    11581 tttaaataat atacataaga gaggtcttta taattataat aatccacatc acaaggatat
    11641 ttttttagtg tatattcact acacattttt ctcaaagttt ttttaaaatt ttttttattg
    11701 tatctttttt ggtctccata aatttttcta aattgagact ctgtaacaca tctaaccctg
    11761 ctaattaaaa gtaatatctc tttttccata ttcgtcatag tacattctcc ttgaagtatt
    11821 atttgcaaag ttgtactaat attatattaa ttttatgaca ttaaatttac aaagaattaa
    11881 aataaaatag ctaattttta tagaattaaa ttctataaaa attagctatc actatgttaa
    11941 atactattat caatcttttt atttaaatta tacattacct tgattttcag aatctttgga
    12001 atctgtattt tcatcagttc ctgttttttc ttttgctttt ttatcttcaa agtttgcaat
    12061 atttaggtta tcaaattctg acatttctat tacaccagat tcttcttttg aatacgatat
    12121 tttgacttta tcaccaacct gagtcaatgg caattcgcta gatacttttg aagtagccct
    12181 aaatattata tctttatttg aatctaaagt tacataataa ttagtgttac cacctcgcac
    12241 atctgggctt attcttgtca ctgtgccttc taatacctca tcttttaaat cattatcaag
    12301 ttttaaatca ttacccttag attctaatgc atccttatag tttcttaatg cttcattctt
    12361 atcttcacct attccaagta cattataatc ttcaacagat acaaatgcaa ctctcttaac
    12421 aagaccagcc ttatctttta atgatgatac atatgttggc tgacccaata tattatacat
    12481 tacagggaac gtcgcttcat aatttttttc ttgaacatta ccttcagctg atttcattgc
    12541 agccgtttca gtagctcctg gttgtttata taatctagct tcttttgttc tagaatcaac
    12601 taacataaat ccaattgtag attcatctcc acctgaagat gttatacctg tataccaata
    12661 agacctgtta tcattgccat aaactaatga tgtaccttct gttggtacta aaactccctt
    12721 ttctgatata acagagttta aaaatccatt aacataaaca ccccagtctt taatctggtc
    12781 tgttacaaag ctttgtggtt gtattctatc cacccattta ggtgtgtttt taacatcata
    12841 aacatttatt tttccagttt ctgcatcaac agtggctatt cctgttgcat ttgctcctcc
    12901 atagccaatt ttatgttcat ataaacttac aacccaataa ggtcttcctt catcatttat
    12961 ttcaagagtg aaatctgtca taccaacatt tacaatacca tgtatgtata aatgtctttg
    13021 taaatcctga tgtaagtagg cttctggttg gtaaactatc tttattggct ttccatctat
    13081 ttcttgaact aattggacgt cttgaggatt actagctgat acttttacat aaccacttgt
    13141 accacttaga gatgttatcc atttaattat gtctctgtga acaagaggcg ctacccagta
    13201 caactctcca tctacatttt gtatatgaaa ttttcctaat ttggatacac tccctattgc
    13261 aggaacttct ccaagctttt tgtcacctaa tttcattgcc atatcttcat ctacaagacg
    13321 aatgtcattt acactgacag ggctaatgtc atcagtaaat ttactttcag ttacttttcc
    13381 caatagttct ctatatgatt ttgcatgaag tacaggtgta gaagttataa agggaactac
    13441 tacaatatac acaagcaaag ctattgctat tgaaaaatta tatttagcca ttttagatgc
    13501 tctttcattt ctatctaaca tcatatctag tattcctgct acaacaaaga aaattattcc
    13561 tactgaaaat aaagatgtaa aatctaatct tagtacaggt aatttaataa atgcataaat
    13621 tattacaatt attaatgcaa ctccatatgt tttaagatat cgtttcattt aatactcctc
    13681 tctaaaaaat gttattatta ttattatatc catatattta caaaaaataa atatttatca
    13741 tatttattat atattaagat atctttatat atttatagtt ctgcttattc aactatattt
    13801 aacattatac gtgtatgtat aaatactttt tatacactgt ttgtgctatc catcccgcac
    13861 ctaaaggagt gggatttttg cactattctg tattatatat atccaaaaat attataaaaa
    13921 tacaaatatt agcagaaatt taaaaactga agaaagtatt ctaactaaga tttacaaatt
    13981 cttaatccta tcgaagttaa actactatct tcagcctaat tatctagcaa tattttttta
    14041 tatgaaaaac tctaaatcaa gtttttaaat gtttgcgatt tttgatacat aagaatgttg
    14101 tctagaatta tattctgata ataaaccttc atactctaag gttaagccag ataaattata
    14161 aaaatcattt ggcgttactt caaatgcttg tttatttaaa atgtctatct cacttttttc
    14221 taacatgtca gcaacaaagt ttgaacatac atatttatat tcagattgtc tctgaatatt
    14281 cattagtaaa tatattaatg ccattgtatc gtaatagtaa tcttctctat aatcactaat
    14341 taattttata tttttatata gattttcata ttgtaaatta tctacttcta acgaatatac
    14401 cctacacaca gtgttttttc ttatagcata caatccttga tttatatttt cttcaacaaa
    14461 tcctccaata aatggattcc ttggatttag ccttccaaaa gaatacattg gttttagatt
    14521 ttcatttaat gatattgaca catgtgtata cagcttttta cttatattcc ttattaagta
    14581 agataatata gttcctgtat atgttgttac aatatagact ttattcatca tttcccccca
    14641 atctagtaac taaatgatat tatacactta caatttaata tcataagata ttctaacata
    14701 ataaatgtgg ttttacaaat tttgatttta aggtacttta atattatata atataataaa
    14761 aatataaata taagttttct atatttttaa ccaacagatg ttttcttcaa attaatcaga
    14821 tgatttagta tatcttgaac ctttccagag tcctttaaat atcctaatgc cccatttatt
    14881 tgtgatttta aatctatttc tacttccata tccaaatcaa catttccttt ttttatagat
    14941 atatttttaa gtgttattgg gtaaagataa cttttttcca aagtaatctt atttccatta
    15001 acctcaaatg gaactttttt attgtagtta cttaatattt tttctagcat tttatcactt
    15061 agtttaaatt ttccaatttt cacattctca agacttacaa ctaagtttcc atcctttaaa
    15121 gtaggtctca attcaagttc atattgacta tttaccaaac caaatacctt atatggtcct
    15181 gctaccttta ttttaccatt tttcatttca acaaaattat tttcaagttc attaattcca
    15241 tgcttctgca tcaatgtata tattaaattt ttaaactctt cctctgaaac agatattttt
    15301 ccaaccattc taagtggatt ttttactacc tccatagaat ttatatatga gccttttgat
    15361 aaatattctt catctatgat tttattattt tgtgaactaa catcatatct ttcttttggt
    15421 gtcaagatat atacaacaat tcctgcaagt actaaaacaa taacaattaa acttaacaaa
    15481 atctttgcaa cctttcccat aatcgtctcc tttacaaatc tgtcatcaga tttaaaataa
    15541 atttagataa ctaacttcac ataatattct taacaatata catactataa tacagtcttt
    15601 taaaaattaa ttcaaccaat ctaatgtttt gtaaataaac tgtaaaaaca tgtttttagt
    15661 ataaaagtta atattttgca taatactctt aattacacct ttattttttt ctaatcttgg
    15721 attaaaatta atattatgca atacagtgta gtgttctgta ttataatcaa attaaatagg
    15781 aggtatagaa tatgtcaaat gaaacgaact catctaactt tataaagaat attattataa
    15841 acgacttaga aacaggaaaa catgacagta tcataactcg ttttccacct gagccaaacg
    15901 gatatttaca tattggtcat gcaaaaagta tatgtcttaa ttttggatta gctaaggagt
    15961 ttaatggaaa agctaattta agatttgatg atacaaaccc attaaaagag gatgttgaat
    16021 atgtagagtc cataaaagaa gatgtaaagt ggttaggatt tgattggaac gagttaaatt
    16081 ttgcatctaa ctactttgat gaaatgtata agagagcttt aatactaata aaaaagggta
    16141 aagcttatgt atgtgatttg acacaagagg aaatgagaga atatcgtggt actctaactg
    16201 aaccaggaaa agaaagtcct catagaaaca gaactattga agaaaacctt gatttatttg
    16261 aaagaatgaa aaatggtgaa tttaaagatg gtgaaaaaac attaagagcc aaaatagata
    16321 tgtcttctcc aaatataaac cttagagacc caattatata tagaatatct cattcaacac
    16381 accataatac aggagataaa tggtgcatat atcctatgta tgcttttgct catccaattg
    16441 aagatgcaat tgaaggaata actcactcta tatgtacttt agagtttgaa gaccaaagac
    16501 ctctttatga ttggtttgtt aaagaatgtg agatggaaaa tatacctaga caaatagaat
    16561 ttgctagact taatataaat aatactgtca tgagtaaaag gaaattaaaa caacttgtag
    16621 atgagggtat tgttgatggt tgggatgacc ctcgtgttcc tacaatatcc ggaatcagac
    16681 gtaagggata tactgcagaa gcattgcgca atttctgtag tgaaataggg gtatcaaaag
    16741 ttaactctac ggtagatagt caaatgcttg attatttcct aagagaaaac ttacaaccaa
    16801 aggctcctct tactatggga gttttaagac ctttaaaact tattataact aattacccag
    16861 aagataagat tgagatgctt gaaatagaga ataatgctaa agatgaatct caaggaaaga
    16921 gattagttcc tttctctaga gaattgtata tagaacaaga tgattttatg gaagaacctg
    16981 ttaagaaata ttttagattt ttcccaggaa atgaagtccg tttaaaaggt gcttattttg
    17041 taaaatgtac tgatgtaatt aaggatgaaa atggaaatgt agttgaaata catggtactt
    17101 atgaccctga aactaagagt ggctctggct ttacaggacg taaggtaaaa tctacaatac
    17161 attgggttga tgctaaatca gctataccat gtgaatttag attatttgaa ccattaattc
    17221 ttgatgatat acctgaaaat gaaggtaaac atttcttaga acaaataaat cctaattcat
    17281 tggaaatatt acaaggtttt gttgaaccta cacagataaa agattctaaa ccttttgata
    17341 aattccaatt tgttagaaat ggattcttta gtatagataa taaatataca actgacgaaa
    17401 aatttgtatt taatagaata gttcctctaa aaagttcttt taaaccaggt aaataatctt
    17461 acaatcaaaa aatgaagact taaaatataa attacttcta ctataaataa acttagttag
    17521 aagtaatttt ttatttgagt cttcatcatt tactttaaat gattaacttt tttcactaca
    17581 gattcccata acttctattc catcttttat gcattctatg ttaagaggaa aatctggtcc
    17641 tttttctccg tcaatatctg ttataagtga atcttcacat tctatatgca cctttttagt
    17701 tttaaagtat agtatttcat ttccattata ttgatctaaa taatcacctc taagcacact
    17761 tatcaaaact ggtattgatt ttggtattgg cattccttta aaaataatta catccaaata
    17821 tccatcatct atttcagcct tatatgctag atttatattt cctgctgttt tgccattaaa
    17881 aatcaacata agatacatat ctccatcata atacatttcc tcagaagata cttttatctt
    17941 aaatttcctc atatacaatg cttcttctat tccctttata taataagaaa ttcttccaaa
    18001 tgaatttttt aagtctgtgt ttatcctttg tgatacatct gtaaacatac cagcacttgc
    18061 aacatttata aagtacttat tattgacttt ccctatgtct attttctttg gttttgaatt
    18121 tatgatttca tttatagctt cttttatatc aaatgaaatt tgaagagcat ttgaaaaatc
    18181 atttgcagtt cctgtaggca aaattccaat tggaattttt atgtctaatt ctttcattgc
    18241 atttactact aaatctacag taccatctcc accagctatc aatatgtgtt cataagaact
    18301 atcaacttcc ttaaatgcat tctttacagg ttctttaata gttaatctat agggtatcaa
    18361 taaataattt ttttcttgat ataattctat gatagtgtct aaatttgata atatcttttt
    18421 ttcacctgaa ttaggattgt atataagttt tacttttttc attatttctc cttactcatt
    18481 ttattctttt agtatccaaa atcttcattt aaaaaaatca catgtattct ttctggtgtt
    18541 aattgtcttt ttataagtgt ataactacag catattcttc ctggacttga acagtctata
    18601 catataccag tagtcttaca tccagtattt gtacttaatc ttttacaatt ggctggagca
    18661 gctattgttt ttgttctttt tatagcttca tctacatctt taactatttt atttactcct
    18721 gctataacta ttactttatc aggtccatat atcatagcag caactctatt cccattccca
    18781 tctaaattgt aaagttctcc atcctctgtt atcgcattag tacttgtaaa ataagcatct
    18841 gcagaaaatg actttctata tatttctttc atttcttctg gtttgatatc ttttgcatat
    18901 ctatcaagaa aattatattt ttctcttata aaatcaatca ctcctgtttc aaataaggtc
    18961 atagaacctc cacatcctac tagagaacct actttaacta tttcttcaat ttttttaaga
    19021 agctcttctt tgttacttac taaataccct ttcatattat tgttttccag agattttatt
    19081 gttttttcta ttcttttttc attaagccaa tttaaatttt gatccatttt aacttccccc
    19141 ttatttttaa tatgtactta attatttata aactttattg tctttataag tttattttag
    19201 tacatctaaa aaaaaataca atataaaact taaatagttt tatataattt tttccaaaat
    19261 aacttactca atcaaaaaag gaaagtagat gtactattct actttcccta tattgtatgt
    19321 agtatttatt gcctaaaatc tatatattaa ttatatgttt catattatat aatatcacag
    19381 ttaattaaaa tgtaatacta tcttcttttt aaacatataa attgtattat taaatttaat
    19441 atatccaact tcaataaatc ttattaattt gatgaagaag atgctatagc tgcacttgtt
    19501 gctgccatta cacatgcaat ttgaatagca acaacaatat ttaaaaatat attattagtt
    19561 atagagccta tattattctc atttcgtatc aaatctgcat aaattgaagc tacaatagca
    19621 gaactaatca ttactctatt actttttcct aaagaccaat ttccaaagcc tttttcttct
    19681 ttaagtttat ttgaaacatt ttttatctct tctattattt catcttctct ataatctaat
    19741 aatgaaattg ctcctattat tggatatcca taataattca ttttacaatc attttcttta
    19801 aatgcttttt taagttcaat agtcttttta catttaagca tagttctatc atcactaaat
    19861 aaaagaattt gggataatgc ttgtaaatca tttcctttat aaaaaccatt ttcatttaga
    19921 aattcataac atttttctat gtattctaaa tcttcatcta aattttttga atgaattgca
    19981 ataagtgcta tattacaata gtcatcacta gaagttagaa atggatgttt tttcctcatg
    20041 taatcatata ttattttcat ttttgatata catgtaagat aatccatttt ctctctattt
    20101 tcataaacta ttgatgctgt aagtggtaaa tatgtatcgc cccaaaactt ttcactttta
    20161 agttctttgt atatatctaa aatcatctta aaactacttt ctggatttga ttcaaacgaa
    20221 agtagtgttg ccatataaaa catattatat cctctaaaat tagagaataa tccagtattt
    20281 tttttaataa gctctattcg ttcttccact aatctaggac ttattctctt gttcttaaga
    20341 gtaaatgcaa gtgcacaact atgttgtatc aatcccattt gccaagaacc tttaacttca
    20401 tttaatgctt tgtaattttc tattaataag tttacttttc catttataaa cgattgttcc
    20461 atattgccct cctagtaata tatctcattg tactaatagt tttatattta ttatatatat
    20521 attaaatact acaatcaata catattactt caaagaacat cattcttcaa caataatgta
    20581 gccttttttg taatgtcttc ccatattatt gactctatca tagtactctg attcactttc
    20641 attactccat ttgggcacaa atacatctat tgcattagaa ttactaaaat acttactaga
    20701 ccccctatcc ataacagttt ttaattttcc atctacaata atcttagttc caaaactcaa
    20761 gtgattgttt gctacaaaac catcttctaa atcatctcct gtagcagtta tcgctccata
    20821 tccattttct tgattaagac ttgtgtaata actaacttca aaagttatag gtactaactt
    20881 ctttatttta atacctaact gattttgtag tttctccttt tgtactttca acttatactc
    20941 atcactattt ttataatctt ccataccttg attatacttg gaattaaagc ttttacctga
    21001 ctttactata gtatctatat ttactataga ttctttacaa tgatctgcat ctatttttgt
    21061 ttctccattt accaataatg gagttaaaca tacactacat acaacacatg taatcaatgc
    21121 ttctttaagc ttcataaatt ccccccttat tattttgata tattagcata tttaatatta
    21181 tatgtctata tttagattta aataccacac ccatttgctt taagaagttg tcttatattt
    21241 aattcacctt aaacacttat aaatcctcta tcttagaatc atatagaata aagcttttat
    21301 cgttaaatat tttttattaa tcttttaaaa tctaaagcta ctttatttaa ttttctcttt
    21361 tttagaattt aagaattaaa attctataat tttaaaacat attgaattta tttttttgag
    21421 atgatataat tttcttaaga ggtggttgat atgataaaaa atacaaaaca aattacagta
    21481 gaagttaatg aaattttatt acaagaaata tctaagataa ctaatgacga aaataatatt
    21541 ttgacagatt tgataaatga atcaattgta aattatattc ttgaaaacaa aaaacataac
    21601 attgaaaata aagatttaga agaagtgatt aaattttaca aaaaagaaaa tactgaaaaa
    21661 cctaaaagtg cagcaagagc tatagctgaa gcaaaaactc ataccctgta ttaatcaaat
    21721 aaaaaagttc ctaaaaacta ggaacttttt tatattaata attattaata tatctcaata
    21781 tttatctcaa atttatcaat ataagcatgt ttaatacaat ctattgtata cttatcttac
    21841 cctagaaata atcaaaacaa aaattatgcc ctttatatct aacaattaat ttacatgatt
    21901 aatatacaaa aattctgact tttaaattcg tatacaatat caaactaaaa taatactaat
    21961 gacaaaccca atataaatta aattcaaaca ggtttgattt tacatcaaac ttattgtatt
    22021 aatattaaat aacaagacaa aatatttata aaaattacaa attttacata aaactttata
    22081 ttttattcat ttaactaatt attgtaaaaa ctatttattt tatgataatt aactacacca
    22141 aattattcat cttttttaat atctttaacc catttttcaa cagagttcaa ttcttcttca
    22201 tttaccccct ttttgaacaa ggatttcata aaactctcaa tagaacttcc atgcatatta
    22261 tctaaaaaag tttttgtttc aaaatgtaaa tactcttctt ctccaataag aactgtataa
    22321 tgtgtatgtc tatcaatctt tcttgcactt aagaattgct tatttactaa tcttgataaa
    22381 agtgttagtg ttgtagtttg cttccaatta tatagttttt ccatagcttc aatgacatct
    22441 tttgatgcta ctgtaaaatc tgaactccaa ataaatttca tgacttttaa ttctgctggt
    22501 ggtatcttag taatagtcat atgattttac actcctctca aacttctaca taattaaata
    22561 ctatattaat agacttttcg agtcaaaggt tttatttaaa atatctcatc caaatttatt
    22621 aatacaaaaa atttatattt ttattcaaaa ttaaacacac aatctattaa tataaagata
    22681 aatatctatt ctataagtat aacagattat ca
//
LOCUS       DAMJYN010000059        22697 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.060, whole genome shotgun sequence.
ACCESSION   DAMJYN010000059 DAMJYN010000000
VERSION     DAMJYN010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22697)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22697)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22697
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.060"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(181..324)
                     /gene="scfA"
                     /locus_tag="PC466_002515"
     CDS             complement(181..324)
                     /gene="scfA"
                     /locus_tag="PC466_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="six-cysteine ranthipeptide SCIFF"
                     /protein_id="HDF2769883.1"
                     /translation="MENKHVKTLSQATLKQSAAKGGCGECQTSCQSACKTSCTVANQE
                     CER"
     gene            complement(390..752)
                     /locus_tag="PC466_002516"
     CDS             complement(390..752)
                     /locus_tag="PC466_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04086 family membrane protein"
                     /protein_id="HDF2769884.1"
                     /translation="MGKSNYIFKGLGYAYIITLAVLLVYNLFLTFTDIGGDNITMVSS
                     FITTISAAIGGFYTSKHMKEKGLMYGLLVGLLYIVCIFLTVFLAQEKFVFEVGMIYKL
                     LLISAAGGIGGVLGVNFK"
     gene            complement(810..1103)
                     /gene="yajC"
                     /locus_tag="PC466_002517"
     CDS             complement(810..1103)
                     /gene="yajC"
                     /locus_tag="PC466_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HDF2769885.1"
                     /translation="MPQQQIIMSIGLWVVVIAIFYFLMIRPQKKKDKQLKEMRSSLSV
                     GDKVITIGGIVANVAKVEDDVVILELGPNRTKVPFEKWAIGTVKSKKEEIEED"
     gene            complement(1237..2358)
                     /gene="tgt"
                     /locus_tag="PC466_002518"
     CDS             complement(1237..2358)
                     /gene="tgt"
                     /locus_tag="PC466_002518"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HDF2769886.1"
                     /translation="MYAVRYELIKTCKQSGARLGRLHTPHGIIETPIFMPVGTQATVK
                     SMTPEELKEIGSQIILSNTYHLYMRPGHELIKRAGGLHKFMNWDKPILTDSGGFQVFS
                     LGPLRKIKEEGVEFRSHLDGSKHFLTPEKAMEIQNALGSDIMMAFDECAPYPSDREYV
                     KNSLERTTRWLKRCKDAHNNTDKQALFGIIQGGMYKDLREQSAKEITSIDLPGYAIGG
                     LSVGEPKPLMYDVLEHTTPLMPQDKPRYLMGVGSPDDLVEGVIRGVDMFDCVLPTRIA
                     RNGTAMTSQGKVVVRNATYAEDFTPLDPECDCYACKNYSRAYIRHLIKANEILGARLI
                     TTHNLHFLLNLMKQIRQAIMEDRLLDFRNEFFAKYGYEI"
     gene            complement(2437..2922)
                     /locus_tag="PC466_002519"
     CDS             complement(2437..2922)
                     /locus_tag="PC466_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769887.1"
                     /translation="MHSLQKQKKNNPILKIAFIFERVLAVVVLIAVFLGTIDVLRLMW
                     GAYIVDFQNPVQYSQLNDFLAQILLLVIGVELVVMLSLHIPGAFIEALLYAIARKMLL
                     LPKNEGMIDVLIGVIAIAGLFAIKKFLVTKDKSALNIMSIHDEEAIKEQQNKEDEDKS
                     I"
     gene            complement(2934..3959)
                     /gene="queA"
                     /locus_tag="PC466_002520"
     CDS             complement(2934..3959)
                     /gene="queA"
                     /locus_tag="PC466_002520"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HDF2769888.1"
                     /translation="MKTSDFKFDLPQELIAQVPIEDRASSRLMVLDKETGNIEHKVFR
                     DIIEYLNPGDCLVLNNTRVIPARLIGEKLETGGKIEFLLLKRTEEDTWQALVKPGKRA
                     KVGTKFSFGNGKLIGEVVDLSDEGSRIIKFLYDGIFEEILDELGNMPLPPYITARLDE
                     KERYQTVYSKHNGSAAAPTAGLHFTEELLNKIKEKGVDIAFVTLHVGLGTFRPVKVED
                     VLNHKMHSEYYMVSQEAADKINRAKENGNNVICVGTTSCRTIESACNEDGKMKETSGW
                     TEIFIYPGYKFKVLDKLITNFHLPESTLIMLVSAICGKDNVLNAYNEAVKERYRFFSF
                     GDAMIIK"
     gene            complement(4277..5296)
                     /gene="ruvB"
                     /locus_tag="PC466_002521"
     CDS             complement(4277..5296)
                     /gene="ruvB"
                     /locus_tag="PC466_002521"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HDF2769889.1"
                     /translation="MQGFEDENRIITSTMKMEDIDIENSLRPKTLEDYLGQEKSKEQL
                     SIFIEAAKSRNEQLDHVLLYGPPGLGKTTLASIIANEMGVNLRITSGPAIERAGDLAA
                     ILTNLNENDVLFIDEIHRINRSVEEVLYPAMEDFCLDIIIGKGPSARSIRLDLPKFTL
                     IGATTRAGMLTNPLRDRFGVICKLDYYTVDELSKIVLRSSSILDAEIQSNGALELAKR
                     SRGTPRIANRLLKRVRDFAQVRADGKITDKVAKDALELLGVDSLGLDFVDEKLLMTII
                     EKFRGGPVGLDTLAASIGEDRNTIEDVYEPYLLQLGFINRGPRGRVAMPLAYEHLKIP
                     YPNEK"
     gene            complement(5403..6005)
                     /gene="ruvA"
                     /locus_tag="PC466_002522"
     CDS             complement(5403..6005)
                     /gene="ruvA"
                     /locus_tag="PC466_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HDF2769890.1"
                     /translation="MYSYIKGTVEEIYIDSIVVENNGIGYKINVSSNTIMNLQVGEAT
                     KIYTKLIVREDDMSLCGFVSREELKMFELLTSVSKIGPKVALSILSFASSAQLGAYIL
                     SEDIGKLSKAPGVGKKTAERIVLELKDKVDKNNIEFEPTLLSQKPTLISQDESVDALV
                     ALGYTLSESKEAVQKCKKDGMNTEAIIKKALTYIMSKSLK"
     gene            complement(5998..6507)
                     /gene="ruvC"
                     /locus_tag="PC466_002523"
     CDS             complement(5998..6507)
                     /gene="ruvC"
                     /locus_tag="PC466_002523"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="crossover junction endodeoxyribonuclease RuvC"
                     /protein_id="HDF2769891.1"
                     /translation="MIILGIDPGIAIVGYGIIEYKNSKFKVIDYGAVTTPAHMNISRR
                     LELVYKGIDTIVKNYNIDEVGMEELFFNKNVKTAITVAQARGVTMLACAHNGKPVYEY
                     TPLQVKQGVVGYGRADKAQVQQMVTSFLSLKKVPKPDDVADALAVAICHAHSNKLEKT
                     LKNIGGKYV"
     gene            complement(6819..7448)
                     /locus_tag="PC466_002524"
     CDS             complement(6819..7448)
                     /locus_tag="PC466_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769892.1"
                     /translation="MFEKKKKELFPWKISALILVGVFVLSSGVYIGTRLKNNGVQTSK
                     VVSASANMDEKSKEAFGLNKNCEVWLQSEGENETNYKRTLTMAGIVPESLLDKTKSEI
                     VSYFKKEYPTKKIKSMDKNEIILVESKYSDNKDVQAMNATIKGKYTIENDNGNIALYK
                     YDDSGSKTLVEKTKIRVDSLPKTVQDEIKKGVVMDTEEEAYSRLEDFAS"
     gene            7651..7974
                     /locus_tag="PC466_002525"
     CDS             7651..7974
                     /locus_tag="PC466_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1540 domain-containing protein"
                     /protein_id="HDF2769893.1"
                     /translation="MERINCNVINCSHNNSHICYADKIFINGEKAHNDRHTCCSSFLD
                     ESIYSNLSSNVNNRNCEELVCTVKNCKYNKDGSLCTLDNILVAPETDRVNLYIETCCS
                     SFECK"
     gene            8242..9096
                     /locus_tag="PC466_002526"
     CDS             8242..9096
                     /locus_tag="PC466_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769894.1"
                     /translation="MSTFYIQFLYFVIYSFIGWCCETTYCSVLQKQFVNRGFLNGPFC
                     PIYGFGALAIVATLTPFVHNIPLLFLFSIIITSIMEYCTSFILEKIFNMTWWDYSKHK
                     FNIHGRVCLENSLMFGVLSLIVMLIVHPIVVDFINSISKNVLFIFAISIEIYFVLDLV
                     ITVHTILQLNGKLKQINLIIKELKDKKEYYKLITQETIENKLESLVENRLDTLEDRFE
                     ILKEKENYRYAKNRIDELKNKLNTLLSNHKLLHRRIIKAFPNISSNKHTDILNKIKEN
                     IKSIKKDK"
     gene            complement(9282..10718)
                     /locus_tag="PC466_002527"
     CDS             complement(9282..10718)
                     /locus_tag="PC466_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HDF2769895.1"
                     /translation="MREVKPISIDILNTFKQVDEDRLNELLADELKHLDRKIVVLDDD
                     PTGVQTVHDISVYTDWDKDSMEQGFNEKNSMFFILTNSRGFTVAQTTKAHKEISKNIV
                     DVSKKVNKDFIIISRSDSTMRGHYPVETNLLKSEVERLSGKLFQGEIIMPFFKEGGRF
                     TIDNVHYVKEGEILVPAGMTEFAKDKSFGYKSSDIGEWCEEKTHGKYKSSDMIYISSK
                     ELRELNIEAITEKLKKAEGFNKIIVNATDYVDVKVFTIAFIRAVNSGKEFMFRSAAAI
                     TKVLGGVSDKEMLTKDELVSKGNTNGGIILVGSHVNKTTQQLEELKNCKYPIEFIEFN
                     QHLVLQENGLKNEVKRVIKVVEEKISSGKTVAVYTRRERFDLDTNDKDKQLMISVEIS
                     DAVTSIIGMLNVRPNFIIAKGGITSSDVGTKALRVKKATVMGQIKPGIPVWMTGKESK
                     FPNMPYIIFPGNVGEISTLRESVEILMG"
     gene            complement(10789..12171)
                     /locus_tag="PC466_002528"
     CDS             complement(10789..12171)
                     /locus_tag="PC466_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HDF2769896.1"
                     /translation="MITGYGLLIAFVISIGILLVSIIKFKVNPFLALLITSIITGFMV
                     RMPINEISTTISTGFGNTLGSIGIVIGLGIIFGNILSESRATESIAKGLLAKTGEKNS
                     ALAVTTAGFLISIPVFMDAAFVIMMPIIKYVSRVTKKSLMVFVCALGVGTIVGHALVI
                     PTPGPLAVAANVNANVGSFILYSIIVAFPAVLIGGWIYGKRFEKYPAYAIDENDREKN
                     LEKGKDSIKIEDDDSSKVPGFGISMFSLLFPILLILISNVFSMFLEKGSTMSGVLAFI
                     GDKNIAILLGILVAIGFLKRYINKPMGDVVIEAADSAGLILLITGSGGAFGSVINASG
                     IGNFLVDTMSGLSISVVVLGFLLSALLRISQGSATVALVTTSSILGPTILATGMSPVL
                     VGLAICAGGVGFSLPNDSGFWVLSRFSGLSVKDTLNSWTIGGTIAGVVAFIMVLLLSV
                     INGIIPLPGL"
     gene            complement(12307..13212)
                     /gene="garR"
                     /locus_tag="PC466_002529"
     CDS             complement(12307..13212)
                     /gene="garR"
                     /locus_tag="PC466_002529"
                     /EC_number="1.1.1.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxy-3-oxopropionate reductase"
                     /protein_id="HDF2769897.1"
                     /translation="MEGYKMKLGFIGLGIMGKPMAKNLLKDGCNLLVYDINKSAVDEL
                     ISCGAKYASVLEMGQECDIVFTILPNGTIVQDILFGMDGLAKTLKEGSIVVDMSSVTP
                     TESILCANKLKDMGLEFIDSPVSGGEPKAIDGTLAFMAGGKEEIYKKVEPFFNIMGSS
                     SILIGDNGSGSVTKLTNQVIVNLTIAAVSEAFVLAAKAGADPEKVYKAIRGGLAGSTI
                     LDAKIPMIMNRDFKPGGKISINLKDIKNVMQTAHNLDVPLPMTSQLLEIMQTLKVHGH
                     LEDDHSGIAQYFEKLAGVEIKKHNN"
     gene            13608..14273
                     /locus_tag="PC466_002530"
     CDS             13608..14273
                     /locus_tag="PC466_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2769898.1"
                     /translation="MATFKRLQEQAYDYLKELILSGEMIENEIYSETKLASEIGISRT
                     PIRDALQRLSQDGFIDIIPSKGFRIHQITANEIVEIFQIRSAIEGFCTFLITSQYKEA
                     RAVETISKLKHLLDKQKDILLGDKNLNSFAEYDTLFHTTIVSYAQNTEFDKMFNNYMY
                     RIKKLALDSLSHEGRLETTLKEHTDIFNNIANGCIEDVYKTTLIHMETPKYINLEDFC
                     NNK"
     gene            14381..14929
                     /locus_tag="PC466_002531"
     CDS             14381..14929
                     /locus_tag="PC466_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769899.1"
                     /translation="MIFLNENVVTNETIDKDYAIEEVRMACKHFGDLYFYFSKVLFEE
                     FGEDKTIEILRKVLFERSEERAIAMRERALENGDELIADNIISTTDVPFLGWVPEFKE
                     LHCPYGASWLLRFEENPWFKKFASLYCDVTDTTVAEVFTGDTSHKITKNILWGDKSCE
                     RIYFHDDKVSEGKYTYGNKNCK"
     gene            15191..15499
                     /locus_tag="PC466_002532"
     CDS             15191..15499
                     /locus_tag="PC466_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769900.1"
                     /translation="MFNKIYEKKEFIVFQVKKGYVVYNTRKSFEEGHTHLKHFEAAKT
                     AIDLAINKKIPRSKDGYYLTSLIRISDDGYYIDKLSELLYVREQKGKKEKYCNSGYQM
                     "
     gene            complement(15661..17451)
                     /locus_tag="PC466_002533"
     CDS             complement(15661..17451)
                     /locus_tag="PC466_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2769901.1"
                     /translation="MKKSKGFKKTIGRLLPFVKKYKFSFIIAIICIISAATMNALAPK
                     TEGLIITQLTKDVISIAKGVPGASVNFDYVTKILVILACIYFANAIFTYTSSFLLTNA
                     IQNTMRDLRNEVENKIRRLPISYFDSNSFGDVLSRISNDVDTISNALQQSFMQIVNSI
                     LVIILALSMMFTINIYMALIALFIIPISYFVSKFVVKKSQSRFSLQQNALGKLNGKVQ
                     EMYTGFNEIKLYGKEEDSIKEFKKVNQELCENGFKAQFISSMMNPMVSLVTYFGIAAV
                     AVVGSIYAVSGGITVGNLQAFVRYIWQINQPLSQMTQLSTVIQSSFAAIERVFEILDE
                     EEEIPDVENPVKIENVKGNVTFEHVNFGYGENSTLIEDLNAEVKSGQMVAIVGPTGAG
                     KTTLINLLMRFYDVKKGAIKIDGVDIRDMKRKDLRSMFGMVLQDTWLFNGTIFENIEY
                     GRFGATKEEIIQAAKVANVHHFITTLPDGYNMFLNEEASNISLGEKQLLTIARAFISD
                     PSILILDEATSSVDTRLELMLQKAMRNLMNGRTSFVIAHRLSTIRNADLILVMNNGSI
                     IEQGNHDELMEKGGFYEKLYNSQFADKESE"
     gene            complement(17451..19178)
                     /locus_tag="PC466_002534"
     CDS             complement(17451..19178)
                     /locus_tag="PC466_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003496244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2769902.1"
                     /translation="MKLILSYLKNYKLLIVLNILAIFSFALVELGIPTIIAKIIDNGI
                     ANQNIAYIKQMGIVIVIISIIGVVGSILLGYCSAKVSTSVTRDIRNDIFEKSQEFSHT
                     EYNKFGISSMITRTTNDAFQIQQFVNILLRTALLTPVMFIISIIMTIRTSVELSIVLA
                     ISVPFIIIGVAIIAKVSQAISSKQQKGLDKLNLISRENLTGIRVIRAFGNDDYETERF
                     EKTNTYYANVSKKLFKLMSITQPAFFLLLNIAVLAVFWISSEKINIGELQVGQLVAFL
                     EYLFHAMFSIMLFSMVFIMYPRAEVSANRIKELLNEEPLIKNPENGIKDTENKGIIEF
                     DNVTFTYPDGEASVLKDISFTAKTGETVAFIGSTGSGKSTLINLIPRFYDVTEGSIKI
                     NGVDIREYDLKALRKKIGFIPQKSLLFTGSIANNIRFGKHKAGESELEYSARVAQAYE
                     FISKKPRKFDELISEGGANVSGGQKQRLSIARAIIRRPEIYIFDDSFSALDFKTDAIL
                     RAKLKKETKDAIVLIVAQRISSIIDADKIIVLNEGQVVGMGTHKELLKNCEIYYEIAT
                     SQLKKEELE"
     gene            complement(19423..19987)
                     /locus_tag="PC466_002535"
                     /pseudo
     CDS             complement(19423..19987)
                     /locus_tag="PC466_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426623.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
     gene            20276..21388
                     /locus_tag="PC466_002536"
     CDS             20276..21388
                     /locus_tag="PC466_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HDF2769903.1"
                     /translation="MKISEVATPNFLLDLDQLEKNIDKIQQICTNNNKQLWPMLKTHK
                     STYIARLQKNAGASGFLVGTLDEGEALIKAGFEDIMLAYPYMGEVNINRIVTMASKIN
                     LICATDNIECAKAYSEAFSKSKIECKLLIIVDCGLHRFGVEPEKVVELATEISKLENI
                     KIVGISSHPGQVYGCSSPEGVPDVCVQEDSSMEKAYKALTDNGFNIEIVASGSTPTVE
                     AEAASKTITAVRPGNYVYYDAIQIGLGCATEDMCALTVVCTVISKNSSGYYLIDCGSK
                     CLGLDKGAHGNSSIVGYGRVCGHPELTIDSLSEEVGKIKVNGETDIKIGDRIRIIPNH
                     SCSTANLTSNLLGFRGDTIEKVIEVDIRENSKQIIL"
     gene            complement(21571..22398)
                     /locus_tag="PC466_002537"
     CDS             complement(21571..22398)
                     /locus_tag="PC466_002537"
                     /inference="COORDINATES: protein motif:HMM:NF033516.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HDF2769904.1"
                     /translation="MSRKYSISSMCKLIGVSRSGYYKWLSYSKKSSDRGIKDRIIKDY
                     IIEIHKKYRGTYGRKRICTYLNKILDSPINHKKVYRLMKELGIKSIIRKKVYRRKFKS
                     YEVYDNILNREFRANQPLEKICMDITYIPIGKKFLYMNVAKDLFNGEIVAYEISTKMD
                     TKLVNKTVNQLINMNLAKDCILHTDQGSQYTSRSYSKRLKDNGIIQSMSRRGNCWDNA
                     PIESFFSHFKSELIYLIDTTDPKEMISLINDYIYFYNNERIQLKNGMSPIEYRTHSA"
     gene            complement(22425..>22697)
                     /locus_tag="PC466_002538"
     CDS             complement(22425..>22697)
                     /locus_tag="PC466_002538"
                     /inference="COORDINATES: protein motif:HMM:NF017834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2769905.1"
                     /translation="AVNLYIKEGYSSYKIAEMLNIRSKTQVQNWVKDYKNKGKTAFNE
                     ETRGRFKNISLENDNRKFKSVEEELKYLRMENEFLKKLSTLLDKSK"
BASE COUNT         7538 a         3853 c         2680 g         8626 t
ORIGIN      
        1 aataaatgct cttatatgat tagatatttt tgcataatta aacgataaga aatcaaattt
       61 aattttacat aagtagaata tatattttta tataataatt gaaaataaaa gaggatacct
      121 cataatgata aaagaatcac tttgagatac cctcttacaa acaactaaat caataatttt
      181 ctatctttca cactcttgat ttgcaactgt acaagaagtt ttacaagctg attgacaaga
      241 agtttgacac tctccacatc caccttttgc agcactttgc tttaaagtag cttgagataa
      301 agtttttaca tgtttatttt ccattttcaa cgcctccatt tctaattgtt tcctattgat
      361 tatatcataa aactacttta atataaactc tatttaaagt tgacacccaa tacgcctcca
      421 atgcctcctg ctgctgatat tagcaataac ttataaatca tccctacttc aaatacaaac
      481 ttttcttgtg ctaaaaacac agtcaaaaaa atacatacta tgtacaaaag tcctactaaa
      541 agtccataca taagtccttt ttctttcatg tgttttgaag tgtaaaaccc tcctatagct
      601 gcagaaatag tagttataaa tgatgagacc atagttatat tatctccacc aatatctgta
      661 aatgtcaaaa ataagttata cactaataaa acagccaaag ttattatata tgcatatcct
      721 agacctttaa aaatataatt agattttccc ataaaaaaac ctcctctcaa attaatatat
      781 attcgagaaa aggcttttaa attactaatt tagtcttctt ctatttcttc ttttttagat
      841 ttaacagttc ctatagccca tttttcaaat ggaactttag ttctatttgg tcctaattct
      901 aatattacaa catcatcttc aactttagct acattagcta ctattccacc tattgtaatg
      961 accttgtctc ctacacttag gctacttctc atttctttta attgtttgtc ttttttcttt
     1021 tgaggtctaa tcattaggaa ataaaagatt gcgattacta ctacccatag acctatactc
     1081 ataattattt gttgctgtgg cattaatttt tcactccttt gtaaattata ctcttttgta
     1141 aatcataata aatgtttata taacaattta ctttctctat ctttgagtac tattgaatat
     1201 tatatattaa aatgattata attaatagtg caaaacctat atttcatatc catattttgc
     1261 aaaaaattca tttctaaaat caagtaatct atcttccatt atcgcttgtc ttatttgttt
     1321 cattaaattt aataaaaagt gaagattatg agtagttatt aatcttgcac ccagtatttc
     1381 atttgctttt ataaggtgtc ttatataagc tcttgaatag tttttacaag cataacaatc
     1441 acattcaggg tcaagtggag taaagtcttc agcataagtt gcatttctaa ctactacttt
     1501 accttggcta gtcattgcag ttccatttct agcgatacga gtaggtagga cacaatcaaa
     1561 catgtctact cctcttataa caccttccac taagtcatct ggactaccaa ctcccattag
     1621 gtatcttggt ttatcctgtg gcataagtgg agttgtatgc tctagcacgt catacataag
     1681 tggttttggt tctccaacac taagcccacc aatagcatat cctggtaaat caatactagt
     1741 tatttctttt gctgattgtt ctcttaagtc tttatacatc ccaccttgta ttataccaaa
     1801 taaagcttgt ttgtcggtat tattatgggc atctttacat ctttttaacc atcttgttgt
     1861 tctttctaaa gaatttttta catattctct atctgatggg tatggtgcac actcatcaaa
     1921 cgccatcatt atgtctgaac ccaatgcatt ttgtatttcc atagcttttt ctggagttag
     1981 aaaatgtttt gaaccatcta agtgtgacct aaattctaca ccttcttctt ttatctttct
     2041 taaaggccct aagctaaata cttggaaccc tccactatct gtaagtattg gtttatccca
     2101 gttcataaac ttatgaagac caccagctct ttttataagt tcatgacctg gtctcatata
     2161 taaatggtat gtgttactaa gtattatttg tgaaccaatc tcttttaatt cttctggtgt
     2221 catagatttt acagttgctt gagttccaac tggcatgaat attggtgttt caataatccc
     2281 atgtggagtg tgtaatcttc ctaaccttgc accactctgc ttacaagtct ttatcaattc
     2341 atatcttact gcgtacataa agttctcctt aaccatattt atttctcatt atttcttaag
     2401 atatatttgt aataagctat tcatataatt tattgtctaa atagatttat cttcgtcttc
     2461 tttgttctgt tgctccttaa ttgcttcttc atcatgaata ctcattatat taagagcact
     2521 cttgtctttt gttactaaaa acttttttat agcaaatagt cctgctatag ctataactcc
     2581 tattaaaaca tctatcatac cttcattttt aggcagtagc aacatttttc tagctattgc
     2641 gtaaagtaat gcctcaataa atgctcctgg tatatgaaga gatagcatta ctacaagttc
     2701 aacacctatt actaaaagta atatttgtgc taaaaaatca ttaagctgac tgtattgtac
     2761 tggattttga aaatcaacta tatatgctcc ccacataagt cttagaacat ctatagttcc
     2821 taaaaatact gctattagaa ctactactgc taaaacacgt tcaaatataa aagcaatctt
     2881 taatataggg ttattctttt tttgtttttg taaactatgc attcattacc tccctacttt
     2941 ataatcatag catctccaaa actgaagaat ctatatcttt cttttactgc ctcattatat
     3001 gcatttaaaa cattatcctt tccacaaata gcacttacta acattattag tgtagattct
     3061 ggtaaatgaa aattagtaat aagtttatct aaaactttaa atttataacc tggatatata
     3121 aatatttctg tccatccact agtttctttc atctttccat cctcattaca agctgattct
     3181 atagttctac aactagtagt accaacacat attacattgt ttccattttc cttcgctcta
     3241 tttattttgt cagctgcttc ttggctaacc atataatatt ctgaatgcat cttgtgattt
     3301 aaaacatctt ctacttttac tggtctaaaa gtgcctaaac caacgtgtag agttacaaaa
     3361 gctatatcta cacctttttc ttttatttta tttaacaatt cttctgtaaa atgtaatcct
     3421 gctgtaggtg ctgctgctga accattatgc tttgaataaa cagtctggta tctttctttt
     3481 tcatctagtc tagcagtgat atatggaggt agtggcatat ttccaagttc atccaatatt
     3541 tcttcaaaaa ttccatcata aaggaatttt ataattcttg aaccttcatc tgataaatct
     3601 acaacttctc caattagctt tccatttcca aaagaaaatt tagtccctac ttttgctctt
     3661 tttcctggtt ttactaaagc ctgccaagta tcttcctctg ttctttttaa taataaaaac
     3721 tctattttac ctccagtttc aagcttctct cctattaatc tagctggtat aactctagta
     3781 ttatttaata ctaaacaatc tcctggattt aaatattcta ttatatctct aaatacttta
     3841 tgttcaatat tacctgtctc tttatctaat accatcaatc ttgagctagc tctatcttct
     3901 ataggaactt gagctataag ttcctgtggt aagtcaaatt taaaatcact tgttttcaat
     3961 gttaaacttc ctctcttaaa atttctccag ctacaataat atcaaaaaaa caacttattt
     4021 tccacaatat taccataatc tatcaagaaa ttgctatttt taacagacac catatccaca
     4081 atatatagat atttttccac gatatacatg tcttatccac aatatataga tacaatacac
     4141 acaattttta tcgtgtttat ccacagtatc tacagatata attaccattt tgtggatata
     4201 tttgaatttt tagccatttt agaaatattt taatttaatg actcttttat tttataaata
     4261 ctcgtataat ctatttttat ttttcattag gatatggaat ttttaagtgt tcatatgcta
     4321 atggcatggc tactcttcct ctaggacctc tatttataaa tcctaattga agcaaatatg
     4381 gctcatatac atcttctatt gtatttctat cttctccaat agaagctgcc aatgtatcta
     4441 aacccactgg tcctcctcta aatttttcta ttatagtcat aagaagcttc tcatctacaa
     4501 aatcgagacc caaactatcg actcctaaaa gttccagagc atcttttgcc accttatcag
     4561 ttatttttcc atcagctctg acttgtgcaa aatctctaac tctttttagt aatctatttg
     4621 ctatccttgg agtccctctt gaacgttttg caagttctaa tgctccatta gactgtatct
     4681 ctgcatctaa gatgcttgaa gacctaagta ctatttttga aagttcatca actgtataat
     4741 aatccaattt acaaataaca ccaaatctat ctctaagtgg atttgtaagc ataccagctc
     4801 ttgtagtagc tccaataagt gtaaatttag gaaggtcaag tcttatgctt ctagcagatg
     4861 gccctttccc tattattata tctaggcaaa aatcctccat tgctggatat aaaacttctt
     4921 caacacttct attgattcta tgaatctcat ctataaataa aacatcattt tcatttaaat
     4981 tcgtaagtat ggctgccaaa tctccagctc tttctattgc gggtcctgac gtaattctta
     5041 aatttacccc catctcattt gctattatac ttgctagtgt agtttttcca agacctggtg
     5101 gtccatataa aagcacatgg tctaactgct catttctcga tttagctgct tctataaata
     5161 tactaagttg ttctttggat ttttcttgac ccaaataatc ttctaaagtt tttggtctta
     5221 aactgttttc tatatctata tcttccatct tcattgtaga agttattatc ctattttcat
     5281 cttcaaaacc ttgcatttat acccctcctc tcgtactttt gaaaatctac tttatatatt
     5341 ttcaaattta cataaactcc ttaaatattg ttttaaaatc caaatattat aaaatccaaa
     5401 tactatttca aggatttact cattatatat gtaagagctt tctttataat agcttctgta
     5461 ttcataccat cttttttaca tttttgaact gcctcttttg attccgacaa agtatagcct
     5521 aaagctacaa gtgcatctac agactcatct tgtgatatca aggtaggttt ttgtgataat
     5581 aacgttggtt caaactctat gttatttttg tctaccttat ccttaagctc taagacgatt
     5641 ctttctgctg tctttttacc aacaccagga gctttggata attttccaat gtcttcactt
     5701 aaaatatatg ctcctaactg tgctgatgat gcaaatgata gtattgaaag cgccacctta
     5761 ggtcctattt tagatacaga tgttagtaat tcaaacatct taagttcttc cctacttaca
     5821 aaaccacaaa gactcatatc atcttctctt acaattaatt tagtatatat ttttgtggct
     5881 tctcccactt gtaaattcat tattgtattg gatgatacat ttattttata tcctatccca
     5941 ttattttcaa caactatact gtctatataa atttcttcta ctgtaccttt tatataacta
     6001 tacatactta ccacctatat tctttagagt tttttcaagt ttgtttgaat gagcatggca
     6061 aatagccaca gctaaagcat ctgcaacatc atctggtttt ggaacttttt ttagacttaa
     6121 aaatgaagtt accatctgtt gaacttgtgc cttatctgct ctcccatatc caactacacc
     6181 ttgttttact tgaagtggag tgtattcata tacaggcttc ccattatgag cacatgcaag
     6241 catagtaaca cctctagctt gtgcaactgt tatagctgtt tttacattct tgttaaagaa
     6301 taattcttcc attccaactt catctatatt gtaattcttt actattgtat caattccttt
     6361 atacacaagt tccaatcttc tcgatatatt catatgggca ggtgttgtaa ctgctccata
     6421 atcgattact ttaaacttgc tatttttgta ttcaattata ccatatccaa ctatggctat
     6481 acctgggtca atccccaata ttatcatttt ttaaaattcc ccctaaaaat aaaagaaata
     6541 ccaaaatgta tttctcataa aaacttatgt tctaaatcat tatatcataa ataatattaa
     6601 caaatcataa aatgctctat gtaaaatata aaatcaaata aaaaagttat atcaaagcaa
     6661 gattttacct caatataact tttatattta ttacaaataa attattgtat ttttatagga
     6721 attaaatgtg actacaattt taatactaat ctatttaata ttaaattatt tattattaac
     6781 ttacttagta tttaacttga aataatatta atttactatt aacttgcaaa gtcttctaat
     6841 cttgaatagg cctcttcttc agtatccata actacacctt ttttgatttc atcttgaact
     6901 gttttaggaa gtgaatctac tcttattttt gttttttcta ctaatgtttt acttccacta
     6961 tcatcatatt tatatagtgc tatatttcca ttatcatttt caatagtata tttacctttt
     7021 atagtagcgt tcattgcttg tacatcttta ttatcactat atttagattc taccaatatg
     7081 atttcatttt tatccatact ctttattttt ttagttggat attctttttt aaaatatgat
     7141 actatttctg attttgtctt atctaataat gactctggaa ctatcccagc cattgtaagt
     7201 gttctcttat agttagtttc attttcgcct tcactttgaa gccaaacttc acaattttta
     7261 tttaatccaa aagcttcttt tgacttttcg tccatattcg cactagcact tacaacttta
     7321 ctagtttgaa ctccattatt ttttaatctt gtccctatat aaactccgct acttaataca
     7381 aatactccaa ccagtattaa ggcagatatt ttccaaggaa ataattcttt tttcttcttt
     7441 tcaaacattg attacgcctc ctttttctat tattttctcc aagctgtaag tttttataca
     7501 atttaggtaa attttagaag aaaatatatt tatatttcaa attactctaa gaatagatat
     7561 tttctaaaag gtagttttct cttaatggtt atattcttgt aattatatgg acataattta
     7621 taataaataa tcgtttagga ggtaataact ttggaaagaa taaactgtaa tgtaattaac
     7681 tgttcacata acaacagcca tatatgttat gcagataaaa tttttataaa tggtgaaaaa
     7741 gctcacaatg acagacatac ttgttgtagt tcatttttag atgaatctat ttatagtaat
     7801 ttatctagca acgttaataa tagaaattgt gaggaattag tttgtactgt aaaaaattgt
     7861 aaatacaaca aagatggtag cttatgtaca cttgataata tattggttgc tcctgaaact
     7921 gatagagtaa acctttatat tgaaacatgt tgttctagtt tcgaatgtaa atagtcatag
     7981 tataaatata agggtgtcaa atgtaattaa actaacatag tgtagagtat ctacaactat
     8041 tagtttgatt atacttgaca cccttattta ttttaaataa aatttcatta ttataaccat
     8101 gtttataatg ttctaactgt aattaaattt gataaatttc tataaattgg tataatcaat
     8161 atgtaaattg aatttagcaa attaatcata aaaataaaat atcgagtata tagtgttata
     8221 ctaactagaa atgaggtgct tatgagtaca ttttatattc aatttcttta ttttgtaatt
     8281 tatagcttta taggatggtg ttgtgaaact acatattgtt cagttttaca aaaacaattt
     8341 gtaaatagag gttttttaaa tggtccattt tgccctatat atggatttgg agcattagca
     8401 atagttgcta ccttgactcc ttttgtacac aatattcctt tgttattttt gtttagtata
     8461 attataacta gcataatgga gtattgtacg agctttattt tagaaaaaat atttaatatg
     8521 acttggtggg attattctaa acataaattt aatattcatg gaagagtttg tctggaaaac
     8581 tcacttatgt ttggtgtatt atcattgatt gtaatgctta tagtacatcc tattgtggtt
     8641 gactttatta actctatctc taaaaatgtg ctatttatat ttgctatatc tatagaaatt
     8701 tattttgttt tagatttagt tatcacagtc catacaattt tacaattaaa tggtaagtta
     8761 aaacaaatca atcttataat taaggaatta aaagataaga aagaatacta caaacttatt
     8821 acacaagaaa ctatagaaaa caaacttgaa tctttagttg aaaatagact ggatactttg
     8881 gaagatagat ttgaaatact taaggaaaaa gaaaactatc gctatgctaa aaatcgtatt
     8941 gatgagctaa aaaataaact taatactttg ctgtctaacc acaaattact tcatagacgt
     9001 ataatcaaag cattccccaa cataagctct aataagcata cagatatttt aaataaaatc
     9061 aaagaaaata ttaaatcaat taaaaaagat aaataataaa ataaacacat aagttaaata
     9121 ataaaaatac taatacataa gattaaggtt tagaatattt tttgtaaaat actctaaacc
     9181 ctaattaata tactattatt tttaatctta atttataatt ttagtttatt ttacttttaa
     9241 cacagtaaat ttaagcgttt aaacttcaat acactaatat actaccccat caatatctca
     9301 actgattctc taagtgtgct aatctctccc acatttccag ggaaaattat atatggcata
     9361 ttaggaaatt tgctttcttt gcctgtcatc catactggta taccaggttt tatctgtccc
     9421 attactgtag ctttttttac tcttagtgct ttagtaccaa catcactaga agtaattcca
     9481 cccttagcta taataaaatt tggtcttaca ttaagcatac caattatact ggtaactgca
     9541 tctgatattt ctacagaaat cataagctgt ttatctttat cattcgtatc caagtcaaaa
     9601 cgctctcgtc tagtataaac agcaacagtt ttaccactgc ttattttttc ctctacaact
     9661 tttataactc tttttacctc attttttaga ccattttcct gaagaactaa atgttgatta
     9721 aattctataa attctattgg atatttacaa tttttaagtt cttctaactg ttgggtagtc
     9781 ttattcacat gtgaaccaac aagtataatt cctccattgg tattaccttt tgatactaac
     9841 tcatccttag taagcatttc cttatcactc actccgccaa gtacttttgt tatggcagca
     9901 gcgcttctaa acataaattc cttaccacta tttactgctc gtataaacgc aattgtaaat
     9961 acctttacat ctacataatc ggttgcattt acaataattt tattgaatcc ttcagctttt
    10021 ttaagttttt ctgttatagc ttcaatattt agctctctaa gttctttaga agaaatatat
    10081 atcatatcac tagatttgta ctttccatgt gtcttttctt cacaccactc acctatatca
    10141 gatgatttat atccaaaaga tttatccttt gcaaattcag tcattcctgc tggtacaagt
    10201 atttctcctt ctttaacata atgtacatta tctatagtaa acctaccacc ttctttaaaa
    10261 aatggcatta ttatttcacc ctgaaataac ttccccgata atctctctac ttcgcttttt
    10321 aataaattag tttcaacagg ataatgtcct ctcatagtag aatcactacg acttatgatt
    10381 ataaaatcct tattaacttt ctttgataca tccacaatat tctttgaaat ttctttatgt
    10441 gcttttgtag tttgagcaac agtaaatccc cttgaattag taagtataaa aaacatacta
    10501 tttttctcat taaaaccttg ttccatacta tccttatccc aatcagtata aacagaaata
    10561 tcatgaactg tttgtacacc tgttgggtca tcatctaata caacaatttt tctatctaaa
    10621 tgcttaagct catctgcaag aagttcattt aatctgtcct catctacttg tttaaaagta
    10681 ttaagtatat ctatgctaat tggttttact tctctcattt aaaacgcccc tttatgtaat
    10741 ttgtatagtc taaatgtaat ttatataata taaacaatag tttgttattt atagacctgg
    10801 aagtggtata attccattta taacactaag caataaaacc attataaatg ctacaactcc
    10861 agcaatggtt cctccaattg tccaagagtt taaagtatct ttaactgata atccactaaa
    10921 tcttgaaagt acccagaatc cagaatcatt tggaagggag aaaccaactc ctccagcaca
    10981 tatagcaagc cctactaaaa ctggtgacat tccagttgcc aaaattgtag gtcctaaaat
    11041 tgatgatgtt gttactaagg ctacagtagc agaaccttga gaaattctaa gcaaagcact
    11101 taataagaat ccaagcacta caactgatat actaagacca gacatagtat caactaagaa
    11161 gttacctata ccacttgcat ttataacact gccaaacgca ccacctgaac ctgttatcaa
    11221 taatattagc cctgctgaat cagcagcttc aataactaca tctcccatag gtttatttat
    11281 gtatctcttt aaaaatccta ttgccaccaa tattccaaga agtattgcta tgtttttatc
    11341 tcctataaat gcaagtactc cactcattgt agaacctttt tctaagaaca tactaaatac
    11401 atttgatata agtataagaa gtattgggaa caataaagaa aacatagaaa ttccaaaacc
    11461 tggtacttta gaagaatcat catcttcaat ttttatgcta tcttttccct tttctaaatt
    11521 tttttctcta tcattctcat caatagcata agctggatat ttttcaaaac gttttccata
    11581 aatccatcca cctataagaa ctgctggaaa agcaacaatt atagaataaa gtataaaact
    11641 acctacattt gcatttacat ttgctgcaac tgctaaaggt cctggtgtag gtattacaag
    11701 tgcatgacct actatagtcc caactcctaa ggcacataca aaaaccatta gagatttctt
    11761 agttactctc gaaacatact taattatagg catcattata acaaaagctg catccataaa
    11821 aactggaatt gaaattaaaa aacctgctgt agttactgct aaagcactgt ttttttctcc
    11881 agtcttagct aacaacccct ttgcaataga ttctgttgct cttgattctg aaagaatatt
    11941 tccaaatatt attccaagtc caattacaat acctatacta cctaatgtat ttccaaatcc
    12001 agtcgatatt gtggttgata tttcatttat aggcattcta accataaagc ctgtaattat
    12061 agatgttatc agtaatgcca aaaacggatt tactttaaat ttaataatcg atacaagtaa
    12121 aattcctata gatataacaa atgctatcaa aagtccatat cctgtaatca taatctttac
    12181 ccctttatca ttctacttta ttatttatca attttatttt tcttttacta tgataactta
    12241 acctcgctgt atttatataa tctaatccta ataatatgta tttaattata ttgatatatt
    12301 taaatattaa ttattgtgtt tttttatttc aacacctgcc aacttttcaa aatactgtgc
    12361 tattccacta tggtcatctt ccaaatgtcc atgtactttt aatgtctgca taatttctaa
    12421 taattgactt gtcataggta gcggtacatc taaattgtgt gctgtttgca ttacattctt
    12481 aatatctttc aaattaatag atatttttcc acctggttta aaatcacgat tcataatcat
    12541 tggtatcttc gcatccaata ttgtactacc agctaggcct cctcttattg ccttatatac
    12601 tttttctggg tctgcacctg cttttgctgc aagtacaaat gcctcagaaa ctgctgctat
    12661 cgtcaaatta actattactt ggtttgtaag ttttgtaaca cttccactac cattatctcc
    12721 aattaaaata gatgagcttc ccattatatt aaaaaatggc tctactttct tataaatttc
    12781 ttccttacca ccagccataa aagcaagtgt accatcaatc gcttttggct cccctccact
    12841 tactggtgag tctataaatt ctaagcccat atcttttaat ttatttgcac acaatattga
    12901 ttctgtagga gtaactgaac tcatatcgac tactatactt ccttctttta aagtttttgc
    12961 caatccatcc atcccaaata atatatcctg aacaatagtt ccatttggaa ggattgtaaa
    13021 tacaatatca cattcttgac ccatttctaa aacacttgcg tattttgctc cacatgatat
    13081 aagttcatcc acagcagatt tattaatgtc atacaccaaa agattacatc catcttttaa
    13141 taaatttttt gccattggct ttcccattat tcctaatcca ataaatccca atttcatttt
    13201 ataaccctcc atatcttcac atttttgaaa acgtttttta tgttttagag tatactacat
    13261 accagtatac cggtcaatat aaaatataaa agtatttatt ttaacaataa atagtaattt
    13321 ttaaagtcat ttattatatt tagtcatcct atataagttt taatacatac tattgttttt
    13381 aaatataata tgctactttt acagttttgt atttttacta atttcaatta gttttaatta
    13441 atctgccttt aatgttaatc atacttcaca cttcaataat tttttatatt ttttaatctt
    13501 atctgcaatt taaattgcaa aagattgacc ttattttcac tatgttgtat gcttaaaatt
    13561 atataagttt ttgtattttt atattgttta ggggggtatt attaagtatg gctacattta
    13621 aaagattaca agaacaagca tatgactact taaaagaatt gatactatct ggagaaatga
    13681 tagaaaatga aatatattct gaaacaaaac ttgctagtga aataggtatc tctagaacac
    13741 ctataagaga tgctcttcaa agacttagtc aagatggatt tatagatata atcccaagca
    13801 aaggatttag aatccatcaa attacagcaa atgaaattgt agagatattc caaatacgct
    13861 ctgcaataga agggttttgt acttttttaa ttacaagtca atacaaagaa gctagggcag
    13921 tagaaactat aagtaaatta aaacatcttt tagataaaca aaaagatatt ttactaggtg
    13981 ataaaaattt aaactcattt gcagaatacg atacattatt tcacacaact atagtttcat
    14041 atgctcaaaa tactgaattt gacaaaatgt ttaacaacta tatgtacaga ataaaaaaat
    14101 tagctctcga ttcattatca catgaaggaa ggcttgaaac aacattaaaa gaacacacag
    14161 atatttttaa taatattgca aatggatgta ttgaagatgt ttacaaaact actctcattc
    14221 atatggaaac tcctaaatac attaatttag aagatttttg taacaataag tgattttagt
    14281 attatacttt catttattaa aaatatatct acctcaaatt aatttcctaa tttataaaaa
    14341 atattctata attatattgt aactaatact attctaagga gtgatttttt tgaacgaaaa
    14401 tgttgtaact aatgaaacta ttgacaaaga ttatgctatt gaagaagttc gtatggcatg
    14461 caaacatttt ggtgacttat atttttattt ttccaaagtg ttatttgaag agtttggtga
    14521 agataaaact atcgaaatac taagaaaagt tttatttgaa aggtctgaag aaagagctat
    14581 tgctatgaga gaaagagctc ttgaaaatgg agatgaatta attgcagaca atattattag
    14641 cacaactgat gttccatttc taggatgggt tcctgaattt aaagagttac attgccctta
    14701 tggagcttcc tggcttttaa gatttgagga aaacccttgg tttaaaaaat tcgcttctct
    14761 ttactgtgat gttacagata ctactgtagc tgaagtattt acaggagata cgtcccataa
    14821 aataacaaaa aacattctat ggggagataa aagttgtgaa agaatatatt tccatgatga
    14881 caaggtatct gaaggtaaat atacttatgg aaataaaaac tgtaaataaa taatttaaat
    14941 tttctatatt catatactat attttgtact ttttcatata aatattataa ctagtctttt
    15001 attttacttt tgtttaacct aaagataatt tacttttaat ctatatgaat tatcatataa
    15061 ataatcagaa agttatcttt ataaattata gttttagatt tataatttat aaaatattta
    15121 tgttctttgt aaaatttttt agaagcttct aatgttatgc tataaaacta tcttgagaag
    15181 ggctgattga atgtttaata aaatatatga aaagaaagaa tttatagttt ttcaagttaa
    15241 aaaaggttat gtagtttata atactagaaa gagttttgaa gaaggtcata cacatttaaa
    15301 gcattttgaa gcagcaaaga cagctattga tttagcaata aataaaaaga ttcctagaag
    15361 caaagatgga tattatctga ctagtttaat tcgcataagt gatgatggtt attacattga
    15421 taagttaagc gaattgttat atgttagaga acaaaaaggt aaaaaagaaa agtactgtaa
    15481 ttctggttat cagatgtaac aagactagtt gtgaattata agtaccaatc ataaatacct
    15541 ttagtcttaa aatcaaagag tatcagtaaa tctataaaaa aacaacttac tgatactctt
    15601 tttaattata tgattaatat ttgaatttga tacaaaattt tatacaaaag tttatgttat
    15661 ctattctgat tctttgtctg caaattggct attataaagc ttctcataaa atccaccctt
    15721 ttccattaat tcatcatgat tcccctgctc tataatactt ccattattca taactaaaat
    15781 caagtcagca ttgcgaattg tagaaagtct atgtgctata acaaaactag ttctaccatt
    15841 cataagattt ctcattgctt tttgaagcat aagttccagc ctagtatcaa cagaactagt
    15901 agcttcatca agtatcaata ttgaagggtc tgatataaaa gctctagcta tggttaaaag
    15961 ctgtttttcc cctagagata tattagatgc ttcttcattt aagaacatat tgtatccatc
    16021 tggaagagtg gttataaagt gatgaacatt tgctactttt gctgcttgta taatttcttc
    16081 tttagtagct ccaaatctac catattctat attttcaaaa atggttccat taaataacca
    16141 tgtatcttga agcaccatac caaacattga acgcaaatct ttacgtttca tatctcttat
    16201 atctactcca tcaattttaa tagcaccttt ctttacatca taaaacctca tcaataagtt
    16261 tattaatgtt gttttacctg ctccagtagg tccaacaata gctaccatct gaccactttt
    16321 tacttctgca tttaaatctt ctattaaagt tgaattttct ccatatccaa aattaacatg
    16381 ctcaaatgta acatttcctt ttacattttc tatcttaact ggattttcaa catcaggtat
    16441 ttcctcttct tcgtctaaaa tttcaaatac acgttctata gctgcaaaag aagattgtat
    16501 tactgtagat aactgagtca tttgtgaaag tggctgattt atctgccata tataacgcac
    16561 aaatgcttgt aaatttccta ctgttatccc tccacttact gcatatatag aaccgacaac
    16621 tgccacagct gcaattccaa agtaagttac taatgaaacc ataggattca tcatacttga
    16681 tataaattgt gccttaaatc cattttcaca aagttcttga tttacttttt taaattcttt
    16741 tatagaatct tcttctttac catatagttt tatttcatta aatccagtat acatttcttg
    16801 tacttttcca tttaattttc caagagcatt ttgttgcaat gaaaatctac tttgagattt
    16861 ttttactaca aatttagata caaaataact aattggaatt ataaaaagag ctataagagc
    16921 catatatata ttaattgtaa acatcattga aagtgccaaa attatgacta agattgagtt
    16981 tacaatttgc ataaaactct gttgcaatgc atttgatatt gtatctacat catttgatat
    17041 acgacttaat acatctccaa aactattact atcaaaataa ctaataggca atcttcttat
    17101 tttattttcg acttcatttc ttaaatctct cattgtgttt tgaatagcat tcgtaagtag
    17161 aaaacttgaa gtatacgtaa aaattgcatt agcaaaatat atacatgcta aaatcaccaa
    17221 tatttttgtt acataatcaa aatttacgga agcccctggt actccttttg cgatactaat
    17281 tacatcttta gtcaattgtg ttattatcaa tccttcagtt ttaggtgcaa gtgcattcat
    17341 agtagctgct gaaattatac atataatagc tataataaag gaaaatttat atttctttac
    17401 aaatggaaga agtctaccaa ttgttttctt aaaaccttta gactttttca ttattctaat
    17461 tcctcctttt ttaactgaga tgttgcaatt tcatagtata tttcacagtt ttttaataat
    17521 tctttatgag ttcccattcc gacaacttgt ccttcattga gtactataat cttatcagca
    17581 tcaataatag aactaattct ctgggcaaca atcaatacaa ttgcatcttt tgtttccttc
    17641 ttcaatttag cacgaagtat tgcatccgtt ttaaagtcaa gtgcagaaaa actatcatca
    17701 aaaatgtata tttcaggtct tcttataata gcccttgcaa tagaaagtct ttgtttttga
    17761 cctcctgata catttgctcc accttcacta atcaattcat caaactttct aggttttttt
    17821 gatataaact catatgcttg tgcaactctt gcggaatatt ctaattctga ctctcctgcc
    17881 ttatgtttcc caaatctaat attatttgct atgctaccag taaaaagcag tgatttttga
    17941 ggtatgaatc ctatcttttt tcttaaagct tttaaatcat attctcttat atctactcca
    18001 tttatcttaa tgctaccctc tgttacatcg taaaatctag gtatcaagtt aattagagta
    18061 cttttcccac taccagtact tcctataaaa gcgactgttt cacctgtttt tgcagtaaat
    18121 gaaatatcct taagtacaga agcttctcca tctggatagg taaaagttac attatcaaat
    18181 tctatgatac ccttattttc agtatcctta attccatttt caggattttt tatcaatggt
    18241 tcttcattta aaagttcttt tattctattt gcagatacct ctgctcttgg atacataata
    18301 aataccattg aaaaaagcat aattgaaaac atggcatgga aaagatattc caaaaatgca
    18361 accaactgtc caacttgaag ctctccaata tttatcttct cacttgaaat ccaaaataca
    18421 gccaaaacag ctatatttaa tagtaaaaag aatgctggtt gagtaattga cataagctta
    18481 aatagtttct tagaaacatt agcataatat gtatttgttt tttcaaatcg ctctgtttca
    18541 taatcatcat ttccaaaagc tctaattact cttattccag ttaaattttc tctcgatata
    18601 aggtttaatt tatctagtcc tttttgttgt tttgaagata ttgcctgaga tacttttgct
    18661 attattgcta ctccaataat tataaaaggt actgatatag ccaatactat agaaagttcc
    18721 acacttgttc taattgtcat tattatactt atgatgaaca taactggagt taataaggca
    18781 gtccttagta gtatattaac aaattgttga atttgaaatg catcattcgt tgttcttgta
    18841 atcattgaag aaattccaaa tttattgtat tcagtatgtg aaaattcttg tgatttctca
    18901 aatatgtcat ttcttatatc tctggttaca cttgttgata ccttagcaga acaataaccc
    18961 aacaatatac tacctacaac ccctataata gaaataataa caatcactat tcccatttgt
    19021 tttatgtaag ctatattctg atttgcaata ccattgtcaa ttattttagc tattatagtt
    19081 ggaatcccca actcgactaa tgcaaaacta aatatagcca gtatgtttaa tactattaat
    19141 aacttataat tctttaaata acttaaaatt aatttcatat ttttctcctt tcttaatttt
    19201 tgagatagtg taatcatgta ataatactaa atttataaat gcttaatttt ataaaaaaag
    19261 gagaaaagag ttaacgcact ctcttctcca gcatattctt tttaatacac cctccgacaa
    19321 gtcgcttata tgttaacata tttgacaagt aatgtcaatt catatagcta aaagtctttt
    19381 aaatgcttca tctcataaca ttgtaacaaa ttggcatgta atttattttt gttttttact
    19441 gtattccaat tttacaagtt ctccaatatt actaactttc ttaaaattca aattagtctt
    19501 atctatacca gacttaaata gtgaaatccc tctccccaat attattggca atatatatat
    19561 ataataatca tcaattaagt tatctttcat aaataatttt actatatcgc ctccaccaac
    19621 tatccaaata tcttttttat ccttcttttt tccaatttgc tcaattaatt ttttaggttc
    19681 taaattagta tactttacat tctccagttg tcccattaat tgtatttgag tatatatagc
    19741 attccttacc cttatagtac cattcatttg ggcttaattc atttgcaatc tgtacatatg
    19801 tggaatttcc cataatgata gtatcaattg tatcgtaaaa agtattataa tcatcttcct
    19861 gctcattctt aaattctgaa gatatctcgt ctaaaaaact tacactgcca ttctcttcag
    19921 ctatataacc atctaaactt gtggcaatat aaagtactac ttttctcatg tttactacct
    19981 ccaacattta tagtgtgatt attctatgta aacatcactt ttttactcat tcaataatac
    20041 cctattaata aatcctcaaa ctaatttaaa taaactttgc ataaaactaa aaatatatta
    20101 tataaataat ttaaaatcac actaacttat tgaaaattct aattattaca aataaatatt
    20161 gctctctgtt aacgctagtt ttataatata attataagct attaatatta taaagccgat
    20221 attactaata taataattat agttaattta cttttgttga aaggtggtaa ataacatgaa
    20281 aatttcagaa gtcgctactc caaatttttt gctagattta gaccagttag aaaagaatat
    20341 agataaaatt caacaaattt gtacaaataa taataaacaa ctttggccta tgcttaagac
    20401 acataaaagt acttacatag cgagacttca aaaaaatgca ggtgctagtg gttttctagt
    20461 tggaacactt gatgaaggtg aagctctgat aaaagcaggt tttgaagata ttatgttggc
    20521 ttatccttac atgggagaag taaatataaa tagaattgtg actatggcat caaaaataaa
    20581 tttaatctgt gctacagata atatagaatg tgctaaggct tatagtgaag ctttttctaa
    20641 atcaaaaata gagtgcaagc tacttattat tgtagattgt ggcttacacc gttttggggt
    20701 tgaaccagaa aaagtggttg aacttgctac tgaaatttct aagctagaaa acatcaagat
    20761 tgttggtata agttcgcatc caggtcaagt gtacggttgt agttctccag aaggtgttcc
    20821 agatgtttgt gttcaagaag attcttctat ggagaaagca tacaaagctc taactgataa
    20881 tggatttaat atagaaattg tcgcttctgg tagtactcca acagttgaag ctgaagctgc
    20941 ttctaaaact ataactgctg taagacctgg aaactatgta tactatgatg ctatacagat
    21001 aggtttaggt tgtgctactg aagatatgtg tgctcttact gttgtgtgta ctgtaatctc
    21061 aaaaaatagc agtggatatt atttaattga ttgtggaagt aagtgccttg gacttgataa
    21121 aggtgcacat ggaaatagta gtattgttgg ttatggtagg gtatgtggac atccagaact
    21181 tactattgat tcactttcag aagaagttgg aaaaattaaa gtaaatggtg aaactgatat
    21241 aaaaattggt gatagaataa gaattatacc taatcattct tgttccactg caaacttgac
    21301 gagtaattta ttaggtttta gaggagatac aatagaaaaa gtcatagaag tagatattcg
    21361 tgaaaattca aaacaaatca tcctttaaaa atatatttat tttgatatta acatcatgaa
    21421 agtatatttt tcttaaaatt attgttaata actaatgtta atgttggata aataaaaaac
    21481 ataaattcta gaaatataaa tttaaaaaaa gaggctgtct caaaattgga tatgtccctg
    21541 tcaagtagac agacttaaaa aaggctatct ttatgcggaa tgagttcgat attcaatcgg
    21601 actcattcca ttttttaatt gtattctttc attattataa aaataaatat aatcatttat
    21661 tagactaatc atttcctttg gatctgtagt atcaattaaa tatattaatt cagatttaaa
    21721 atgactgaaa aaactttcta taggagcatt atcccagcag ttgccccttc gggacataga
    21781 ttgtataata ccattatctt taagcctttt agagtaagat ctacttgtat attgtgaacc
    21841 ttgatctgta tgtaaaatac aatctttagc taaattcata tttattagtt gatttactgt
    21901 tttattaact aatttagtat ccatttttgt acttatctca tatgccacta tttcaccatt
    21961 aaataaatct ttggctacat tcatgtataa gaatttttta ccgataggta tgtatgttat
    22021 atccatacaa attttttcta atggttgatt agctctaaat tcacgattta atatattatc
    22081 atatacctca tatgatttaa acttacgtct atatactttc tttctaataa tagatttaat
    22141 tcctagttct ttcatcaacc tatatacttt cttatgatta atagggctat caagtatttt
    22201 atttaaataa gtacaaattc tttttctacc gtaagttcct ctatattttt tatgtatttc
    22261 aattatataa tccttaataa ttctatcttt gataccccta tcggaagatt ttttagaata
    22321 acttagccat ttatagtaac cgcttcttga cacacctatc aacttacaca tactagaaat
    22381 actatacttc ctagacataa gtttaattgt tttaaattta tcgcttactt tgacttgtcc
    22441 aatagggtac ttaacttttt taaaaattca ttctccatgc gtaagtactt caattcttct
    22501 tcaacagatt taaattttct attatcattt tctagactaa tatttttaaa tctgcctcta
    22561 gtttcctcat taaatgcagt tttaccttta tttttataat cttttaccca gttttgaact
    22621 tgtgttttgc ttcttatatt cagcatctca gcaattttgt atgatgagta tccttctttt
    22681 atatataaat ttacagc
//
LOCUS       DAMJYN010000060        22686 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.061, whole genome shotgun sequence.
ACCESSION   DAMJYN010000060 DAMJYN010000000
VERSION     DAMJYN010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22686)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22686)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22686
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.061"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(104..619)
                     /locus_tag="PC466_002539"
     CDS             complement(104..619)
                     /locus_tag="PC466_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HDF2769906.1"
                     /translation="MDFLAKYKVLKKQNSSKSCLVCGTQNELGLKADFYELENGELVS
                     ICNTKDWHQSYPGRVHGGMSAAILDETIGRAVSINDDQIWGVTVSLELKYKKPVPTDA
                     TIKVVGRITKENRKLFEGTGEIILPNGDIAVTATGKYMKMPIGQIAEGDFSNEEWFFE
                     ESKEKVEYIEL"
     gene            complement(982..2052)
                     /gene="leuB"
                     /locus_tag="PC466_002540"
     CDS             complement(982..2052)
                     /gene="leuB"
                     /locus_tag="PC466_002540"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HDF2769907.1"
                     /translation="MNCNIAVIKGDGVGPEIIDEGIKVLNKICCKFNHRFDCEYVLAG
                     GCAIDEIGEPLPNKTVETCRKNEAVLLGAVGGPKWDKCKGDKRPESGLLKLRESLGLF
                     ANLRPATMYESIKEASPLRTDIVEKGIDFVVVRELTGGIYFGERGRKIIDGIENAYDV
                     EIYNENEIRRIGKRAFEIARNRNKKLISVDKANVLESSRLWRSIMEDLAKEFEDVELS
                     HMYVDNAAMQVVKDPSQFDVIVTNNIFGDIISDEASMITGSIGMLPSASLREDSFGMY
                     EPIHGSAPDIAGKDIVNPIATILSVSMMLRHSFNLEEEAKCIEDAVQSVLNKGYRTID
                     IYNGVGNVVGTRAMGELIVNEI"
     gene            complement(2059..2550)
                     /gene="leuD"
                     /locus_tag="PC466_002541"
     CDS             complement(2059..2550)
                     /gene="leuD"
                     /locus_tag="PC466_002541"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HDF2769908.1"
                     /translation="MIANGSVFKFGDNIDTDVIIPARYLNIADYKELATHCMEDIDDK
                     FISKVKKGDIIVATKNFGCGSSREHAPIVIKESGVSCVIASTFARIFFRNSINIGLPI
                     LECEEAANNIDEGDNIEVDFSTGVIKNITKEKEYKAEPFPEFMQNIILNEGLINSIKA
                     NRG"
     gene            complement(2565..3842)
                     /gene="leuC"
                     /locus_tag="PC466_002542"
     CDS             complement(2565..3842)
                     /gene="leuC"
                     /locus_tag="PC466_002542"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase large subunit"
                     /protein_id="HDF2769909.1"
                     /translation="MGMTMTQKILAKHAKLNEVKKGQLIEADLDVVLGNDITSPVAIR
                     EFEKLGIEDVYDKTKVVMVLDHFTPNKDIKSAEQCKFTRSFAKSKGVVNFFDVGDMGI
                     EHVLLPEKGIVTAGDVIIGADSHTCTYGALGAFSTGVGSTDMGAGMATGKCWFKVPGA
                     IKFVLKNKPNKWISGKDIILHIIGEIGVDGALYKSMEFCGDGVEYLSMDDRFTICNMA
                     IEAGAKNGIFPVDDKTMEYINSHKCSTITKDVNIYEADEDAVYDEVYEIDLAELKETV
                     AFPHLPENTRTVDEIDKDIKIDQVVIGSCTNGRISDLEVVAEIMKGKKVADGVRVMIF
                     PGTQKVYLEAIEKGYITTFIEAGAAVSTPTCGPCLGGHMGILAAGEKSISTTNRNFVG
                     RMGHVDSEVYLASPAVAAASAITGKISKPSEII"
     gene            complement(3799..5541)
                     /gene="leuA"
                     /locus_tag="PC466_002543"
     CDS             complement(3799..5541)
                     /gene="leuA"
                     /locus_tag="PC466_002543"
                     /EC_number="2.3.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HDF2769910.1"
                     /translation="MKCGKYKKYDKMQIVNRKWPDNEIFKAPIWCSVDLRDGNQSLPT
                     PMSVNEKVRMFKMLIDTGFKEIEVGFPSASNTEYTFLRKLIDENMIPDDVTIQVLTQS
                     RAHLIEKTFESIKGCKKAIIHLYNSTSVLQRDVVFNMSKQEIIDIAVEGAKLFNEEVK
                     KYPETEFTFEYSPESFTGTEMDYALEICEAVIDVWKPTPQKKVIINLPSTVEMATPNV
                     YADQIEWFCKNISCRDSIILSLHTHNDRGTCTAASELGLLAGADRLEGTLFGNGERTG
                     NMDIVNVGLNLYTQGIDPELDFSNIDKIIGIYEDCTKLMVHDRHPYAGNLVHCAFSGS
                     HQDAIRKGMIAMKNRDNDYWEVPYLPIDPHDIGREYKEIIRINSQSGKGGAVYIMETD
                     YGFMIPKNMHSDFGNVVKMESDRIGEELSSEAIFNLFKKEYIEVESPYKVKKYKIKSM
                     DELNYENDDSNDTNMIEMTARISYMGNEQRIVGIGNGPVDSFNNALKQCGMKDYKFRY
                     YWEHALEEGSHSRGVAYVGIEHNNEVYFGVSISENINTAAINALMNAINKSYIEEEIK
                     NGDDYDAENISQTC"
     misc_binding    complement(5665..5911)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(6059..6505)
                     /locus_tag="PC466_002544"
     CDS             complement(6059..6505)
                     /locus_tag="PC466_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769911.1"
                     /translation="MSKNKFIYMNYYDNGYFKKGMTIYMVLALIILATIFIYSTTILY
                     ILCIITAVFLFKQGRDFSNKYEGKVYITLDNHSILINNQCIFSIKSKQSQKFNYKIIE
                     KIEVVKNILNIYTDESNYKIRLRALSLEDEKKLLNIIDEKMKKFKA"
     gene            complement(6526..7245)
                     /locus_tag="PC466_002545"
     CDS             complement(6526..7245)
                     /locus_tag="PC466_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase"
                     /protein_id="HDF2769912.1"
                     /translation="MKKSIMDVHCHTLISGHAHSTFKENVEEASKKNIKYLGISDHGP
                     NMPGGPHPFYFYNLHLLPREVQGVKILRGIEGNIMDYSGNLDVQEDMLQHLDYIIASL
                     HRPCIASGTKEENTNAILKVMDKPKVKIIGHPDDSRYPLDYEPIVKKAKDKNILLEIN
                     NSSLSSNSHRTGTWENVSHMLTLCKTYGTRVILGTDSHICYSIGEFENAEKVLEAVDF
                     PDELVINYHEDEIIEFFDINF"
     gene            complement(7363..8637)
                     /locus_tag="PC466_002546"
     CDS             complement(7363..8637)
                     /locus_tag="PC466_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HDF2769913.1"
                     /translation="MFIMENDLTMQELLDQQEQVFSKVKVGELTTGKITAVRNDEVQL
                     GLDYGFDGIIPISELNIEKNQYIEDIYHIGDEITAVITKVSQKDGTITLSKLQLDKRN
                     DFAELQKAYDEHRIITVNVEKNIDKGVFANYNTYTFFIPISQLDTKFITDTSKFVGLN
                     LEVYIKELDVRKNRLVASHRDVLQERINKEREERRAQIKAEKEAERARIKQEREEEKA
                     RIKAAKEDLFNSLEVGQKRDGKVTKIMPYGAFVDIGGIEGLAHINNLAWTRVESVEDV
                     VSEGQEVEVYVLDVNKETKKIALALKDINNDPWDLIAKEVQIDDVVNAKVLRIIEKGA
                     FVQIKEGVDAYLPISELSDTRVAKVTNVVNIGDEVKVKILDFKPKTKRMLVSIKEATR
                     EPEEDITEYLEVEESLGSIGELFKDKFKDLEV"
     gene            complement(8837..10204)
                     /locus_tag="PC466_002547"
     CDS             complement(8837..10204)
                     /locus_tag="PC466_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF2769914.1"
                     /translation="MENSNTNLGSESVGKLLFKLATPAIIAQIVNVLYNIVDRIFIGR
                     MENGEVAMAGVGVAFPIIIIITACSYLIGMGGGPLAAIKMGEQNNDEAEKIMSNSFSV
                     LVILAILLTIGFKIGKEPLLWMFGASESTIRYSMDYLNIYLIGTVFVQISMGMNTFIN
                     TQGFATTGMMTVAIGALINIILDPIFIFGFNMGVKGAALATIIAQGVSAIWVLMFLFG
                     KKSILKIKKKYMIPKASIILPVLGLGISPFIMQSTESLVLIALNSKLQMYGGDLAVGS
                     MAIMSSIMQILMLPNMGVTQGAQPIISYNYGSGQLDRVKKTFKLCLLSCFTYSTILWL
                     LLMIFPAFFVSIFNKNPQLLSMTSWSIKIYFAGAFMFGIQIACQQTFLALGKATISLV
                     LALLRKIVLLIPLIFILPTFFNEKLFAVILAEPVADITAATITAISFFIFYKCFLSKP
                     KAIKE"
     gene            complement(10454..10918)
                     /locus_tag="PC466_002548"
     CDS             complement(10454..10918)
                     /locus_tag="PC466_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small multi-drug export protein"
                     /protein_id="HDF2769915.1"
                     /translation="MSLRIGGNSLGYLHILILSMVPVTELRGAIPIGIAMGLNPIWVY
                     VFSVIGSTLVSIPLILTFRHVLQFLRGKKLFKGIADVIDRKINSRMKKLKSVSIIGII
                     LFVGIPLPTTGTWTASAIASILKMRIKDAFMGVFLGNLLSGVIVSALSLHII"
     gene            complement(10923..11552)
                     /locus_tag="PC466_002549"
     CDS             complement(10923..11552)
                     /locus_tag="PC466_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family hydrolase"
                     /protein_id="HDF2769916.1"
                     /translation="MKKSVLLLDVDYTVINTDSMIDFFIYSLKNKTFKTIIKLPYIIF
                     ILFMYLIRMIPLKKAKEAIFYPIVDFSEEDLKKFFDDCIMKKINESMKKVIYKNKEED
                     NVIIMITASPYAYMKYFKYYGLADKVIGTEFFYENSRYKNQFIGENCKGIEKVKRIKA
                     VLGKLGIEIDYENSYAYSDSKSDLPMLSLTKNAFLVSKKDGEVIEQINS"
     gene            complement(11586..12473)
                     /locus_tag="PC466_002550"
     CDS             complement(11586..12473)
                     /locus_tag="PC466_002550"
                     /EC_number="2.4.2.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decaprenyl-phosphate phosphoribosyltransferase"
                     /protein_id="HDF2769917.1"
                     /translation="MKQTNTSIRLLTKISDYIKLMRIKQYIKNFFVFSAIIFSNNILN
                     INLFLNTFIAFVCFCLMSSSVYALNDAIDMDKDKKHPKKCNRPVASGRISKKSANILF
                     VVLALISVCLSTVVSFNLSIILSLYLINNILYSLKLKNIILLDVFSISLGFILRVYAG
                     CVAISVSLSNWIILCTFFLSLYLALGKRKKEIETLRDDAVEHRKILEDYDIENLNQMM
                     IVILSSTIVCYSLYSTSNPEKPHMIFTTIFVVYGVLRYNYIINTTNENNPTDIVLKDN
                     ALKINVILWIITCLIILIF"
     gene            complement(12502..13740)
                     /locus_tag="PC466_002551"
     CDS             complement(12502..13740)
                     /locus_tag="PC466_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769918.1"
                     /translation="MDGDILMSKILKYKNEMFLFILVVITYLIITKIFFSKTTIFYNL
                     NNTYDVLLDTDTGVLFNLNVFAISQDNSKHILFSAIISIFAYPIYLFCTSIANPGTTD
                     FNSAYGFGLICLQIITSAMSITLVFNHIKKIKMQRLTLILLTMIMIFSFPQLFMTLNV
                     ERFIYSQFSLIFFIVIANKMKGKNSYLVELAAIPLFGITISNIYLYFFNMIFEFKLKI
                     GKMLKHLITFILMAYICVVSTKSYESFMNLGNVIQYDTKFISGEPILEKIAMIIERLL
                     YSVFYFPGASIKKGLFLQNGEVATIPVILTLLALCFCVLSVIENSEKRVPKLCMGIII
                     FNLTLHGIVGYNLVNSSIMAINFSFAVIILLAYFTKALRKNEKNMYNIFLSLLLVTIV
                     ISNVNGFIEILNIGIKSYPV"
     gene            complement(14124..15266)
                     /locus_tag="PC466_002552"
     CDS             complement(14124..15266)
                     /locus_tag="PC466_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HDF2769919.1"
                     /translation="MRYVEYGKTGKMVSVVGYGGLRFDLEKSNQENADLVKYAYEKGI
                     NYFDTAPGYCDDRSEDIFGLAFRQMIKEGKTDFYVSTKEKPKACDTSEKAIEAVKKSI
                     ERLGVSKINFYHVWNIRKMEHYELAMRPGGQYEGLLKCKEEGLIDHIVFSSHQPGDEV
                     IDILSENKFEGVTMGINILNFPYRLKGAKYAVDNGYGVVAMNPLSGGTIPKYNKELSF
                     LSKDGESTIESALRFNIGISQISISLIGFNKKQDIDDACKIADENRIYSDEDIHDIET
                     RLNKNMNEICTGCGYCKVCPKGINTPAYMLFYNEKQMFKKSDEEMTKLVYGLGHWNYT
                     MNSKAKAKECISCGKCEVECTQHLPIIDRLKEIKKWEEDGANSVKV"
     gene            complement(15407..16273)
                     /locus_tag="PC466_002553"
     CDS             complement(15407..16273)
                     /locus_tag="PC466_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HDF2769920.1"
                     /translation="MDNYKKVKQVLWIILFANFAVALLKIIIGNQIKSYSMTADGFHS
                     LSDGASNIVGLIGIFFASKPKDKNHPYGHKKFEIITSLFISGMLFVIAIKIILSAVLR
                     IANPVVPAITIESLIALIITLFINIFVCMYEYRIGTKLNSYVLISDSLHTRSDIFVSL
                     GVLVTLVGVKLGFPVIIESIVPIIISAFIIYSAYGIFRPSIGILVDRVAVDEDYIKEI
                     VFEFNEVRDVHNIRSRGSKSSIYIDMHVMVDPFISVEQSHDLTHKIEKQIQEEINENA
                     QVIVHIEPFYSF"
     gene            complement(16607..18154)
                     /locus_tag="PC466_002554"
     CDS             complement(16607..18154)
                     /locus_tag="PC466_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HDF2769921.1"
                     /translation="MANFFNFILLQKDKIIELLIQHMSLTVTSILIAIIVGVPLGIII
                     SRISSLRKFVLGFVNLVQAVPSMALLGLLVPILGIGSKPAIFMVVVYSLLPIVKNTYI
                     GITSIDPVVLESAKGIGLTRNQTLFKIQFPLALPIIMGGVRISAVTAVGLMTLAAFIG
                     AGGLGYLVFSGVQTVNNNMILAGAIPSCIIALLVDYLFSKIEVAVTPKGLNPKAPKKN
                     YIALKVISVVVVVSMLFVVFSSSFSSKKDTITIGSKDYTEQLILGNVYAELVEKNTNL
                     KVKKNLNLGGSSVAFNAIKSGELDMYVDYTGTLLVNVMKHAPIKDADEAYNVVKDTME
                     KENQLTLLDPLGFNNTYTLAMMPETAEKYGINTISDLTKYGKEFTFSPTLEFENREDG
                     LVGLSRDYGLKFKDVKAMNGSLRYTALDNNESQVIDAFLTDGLIKKFNLKILEDDKNF
                     FVPYYAAPLVREDTLKKYPELEKVMNMLSGKINEETMRELNYQVDELGKSPEEVAHSF
                     LVKEGLV"
     gene            complement(18147..19283)
                     /locus_tag="PC466_002555"
     CDS             complement(18147..19283)
                     /locus_tag="PC466_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2769922.1"
                     /translation="MIEIRNVTKKIGNNVILDDISLVVETGTLVVLIGSSGCGKTTTL
                     KLINKLIKPTSGEIYINGKPISQENEIELRRKIGYVIQNTGLFPHLTIKENIELIPRL
                     KKEKSVEEIEKRTLQLLEMVGLDSDEFLNKYPSELSGGQQQRIGVARAIATDAEIILM
                     DEPFSALDPITRTSLQEQLFSLQDELKKTIIFVTHDMDEALKIADKICIMKDGRIAQY
                     DTPENILRKPANDFVKDFIGEDRVWDNPEYIKARDIMIKNPIAVNSTRTVTQGIEIMR
                     TSKVDSLLIIDRAKTLKGIVTVKDMKDIDDKSILLADIMSSEPLHVNEGDNLVEILNV
                     MNRNSVGYIPVISDENKLVGLITRSSLLSVLSEQFLEMEVSVLG"
     gene            complement(19539..20636)
                     /gene="dinB"
                     /locus_tag="PC466_002556"
     CDS             complement(19539..20636)
                     /gene="dinB"
                     /locus_tag="PC466_002556"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HDF2769923.1"
                     /translation="MKHYRKIIHIDMDAFYASIEQRDNKKLKGKPVIVGGNPQSRGVV
                     ATCSYEARKFGIHSAMPSAVAYNRCPYAVFVRPRFDVYKSVSEQIRDIFYRYTDLVEP
                     LSLDEAYLDVTKNKKNIDSSIEIAKQIKKDIFREVGLTSSAGVSYNKFLAKIASDLRK
                     PNGLTVITEENAQDFLDKLPVNKFFGVGKVTSNTLKNLGIKTGYDLRCLNLFELENIF
                     KKRGYELYKFARGIDDRPVEPNRVRKSVGAETTLSHNLDIDEEETRNILDELCEEVCH
                     RLKSSEKFGKTLTLKIKYEDFTKITRSLSLEHYIDEYNDIRSGVDNLLRNVEVNGKQI
                     RLLGVTISNLSDKKETYKDITLFEYMDSIQM"
     gene            complement(21026..22531)
                     /locus_tag="PC466_002557"
     CDS             complement(21026..22531)
                     /locus_tag="PC466_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003374392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HDF2769924.1"
                     /translation="MKVGFDHKKYLEEQSKYILERVNNFDKLYLEFGGKLMGDLHAKR
                     VLPGFDENAKIKVLQHMKEKVEVVICVYAGDIERNKIRGDFGITYDMEVLRLIDDLRG
                     YELDVNSVVITRFEGQPATTVFINKLERRGIKVYKHYPTKGYPSDVETIVSDEGYGAN
                     EYIETTKPIVVVTAPGPNSGKLGTCLSQLYHENKRGNVVGYSKFETFPVWNVPVKHPL
                     NIAYEAATVDLKDVNMIDSFHLETYGEMSVNYNRDLELFPVLKKIIEKITGKESIFQS
                     PTDMGVNRVGFGIIDDEVIRKASIEEIIRRYFKTACEYKKGQVDKGAYDRMKMIMEEL
                     NLKPEDRNVVLPARNYSNKLKESADKNDTCPVVALELEDGTILTGKGSDLMNGTAAVV
                     LNAIKHLANISDDMHLISPVILEPIINLKTKTLASRNVSLSCQEVLTALSICAVTNPT
                     AQFAMEKLALLKGCQAHSTTILNRDDEQTFRKLGIDVTCDPEYPSQNLYYS"
BASE COUNT         7453 a         4109 c         2360 g         8764 t
ORIGIN      
        1 tagtataact aatttatttt tatcttgtat ttttattgta tttttgaatt ttattttttc
       61 taaatataaa atttatgttt taaaatataa aatttttatt taatcaaagt tcaatatatt
      121 ccactttttc tttcgattct tcaaaaaacc attcttcatt agaaaaatca ccttctgcaa
      181 tttgtccaat aggcattttc atatactttc cagttgctgt cactgctata tctccatttg
      241 gtagaattat ttctcctgta ccttcaaata attttctgtt ttctttagtt attcttccaa
      301 caacttttat agtagcatct gttggtactg gtttcttata tttcaactct aaagatactg
      361 ttactcccca tatttggtca tcatttatac ttacagctct tccaatagtc tcatctaata
      421 ttgcagcaga catacctcca tgaactctcc caggataact ttgatgccaa tcctttgtat
      481 tacaaattga tacaagctct ccattttcaa gttcataaaa atctgcttta agtcctagct
      541 cattttgtgt tccacaaact aaacaagatt tactactatt ttgcttcttc aaaactttat
      601 actttgccaa aaaatccatc tcctaaccga cattagtagt cgcttaatat taaataattc
      661 taaaatatat tatataatat taataaaatc cctgcaaact tctaataata aaaataggct
      721 acttcaatat gataagttta atttaaagta ttattttcca aaaaataact ttatcaaaat
      781 agaaactcaa agtagatata agcctctttt tcgctattaa aatagtaaaa atatatttga
      841 cttaatataa aaaagagtgt ctcattaact aataaagttt attttgagac acccctcata
      901 aaacaaatta tactacaata gatttttact aattctacaa gttatatatt taaattatat
      961 tattcaaatt aaactataat tctaaatttc atttactatt aattcgccca ttgctcttgt
     1021 tcctacaaca tttcccacac cattatagat atcaatagtt ctataacctt tattgagtac
     1081 actttgtaca gcatcttcaa tacacttagc ttcttcttct aagttaaaac tatgtcttaa
     1141 catcatgctt acagatagaa tagttgcaat tggatttaca atatcttttc cagctatatc
     1201 aggcgcactt ccatgtattg gttcatacat accaaaacta tcttctctaa gtgatgctga
     1261 tggtaacata cctatagaac ccgtaatcat agatgcttca tcagatatta tatctccaaa
     1321 tatattatta gtcactatta catcaaattg gctagggtct tttacaactt gcatagcagc
     1381 attatcaaca tacatatgtg acagttctac atcctcaaac tctttagcta agtcttccat
     1441 tatacttctc caaagtcttg aactctcaag cacatttgcc ttatctacac ttataagttt
     1501 tttatttcta tttctggcta tttcaaaagc tctcttacca attcttctta tttcattttc
     1561 gttatatatt tctacatcat aagcattttc gataccatca atgatttttc ttccacgttc
     1621 tccaaaataa atgccccctg ttaattctct tacaacaaca aaatcaatgc ctttctcaac
     1681 tatatccgtt ctaagtggtg aagcttcttt tatactttca tacattgtag ctggtcttaa
     1741 atttgcaaat aaacccaatg actctcttaa ttttaaaaga ccagactctg gtcttttatc
     1801 tcccttacat ttatcccact ttggtcctcc aacagcacca agcaatacag cttcgttttt
     1861 tcgacaagtt tcaacagttt tattaggtag aggttctcca atttcatcaa tcgcgcatcc
     1921 tccagctaat acatattcac aatcgaatct atgattaaat ttacaacaaa ttttatttag
     1981 aacctttata ccttcatcta taatttccgg tccaacacca tcacctttta tgactgctat
     2041 attacaattc atactccact accccctatt tgcttttatt gagttaatta agccttcatt
     2101 taatataata ttttgcataa actcaggaaa tggttctgct ttatattctt tttcttttgt
     2161 tatatttttt atcacacctg tagaaaaatc tacttctata ttatcccctt catctatgtt
     2221 attggcagct tcttcacatt caagtatagg aagccctata tttatagagt ttctaaaaaa
     2281 tattctagca aaagtagaag caatcacaca ggatactcca ctttctttta ttacaattgg
     2341 tgcatgttct cttgatgaac cacaaccaaa gtttttagtt gcaactataa tatctccttt
     2401 ttttacctta gaaataaatt tatcatcaat atcctccata caatgcgttg ctagttcttt
     2461 ataatcagct atatttaaat atctagctgg tattattaca tctgtatcta tattgtcacc
     2521 gaatttaaaa acacttccat tggcaatcat aaattttacc tcccttaaat tatttctgat
     2581 ggttttgata tttttccagt tatagctgat gctgctgcta cagctgggct tgcaagatac
     2641 acctctgaat caacatgccc cattcttcct acgaaattcc tatttgttgt tgaaatggat
     2701 ttttctcctg ctgcaagtat acccatatgt ccccctagac atggaccaca agttggtgta
     2761 gaaactgctg ctcctgcctc tataaaagtg gtaatatacc ctttttctat agcttcaaga
     2821 tatacttttt gagttccagg aaatatcata actctaactc catctgctac ttttttgcct
     2881 ttcattatct cagctactac ttcaaggtct gatattcttc catttgtaca agaacctatt
     2941 acaacttggt ctatctttat atccttatct atctcatcta ctgttctagt attttcagga
     3001 agatgaggaa aggctactgt ttcttttagt tcggctaaat ctatttcgta tacttcatca
     3061 tagactgcat cttcatctgc ttcatatata tttacatctt ttgttatagt tgaacactta
     3121 tgtgaattta tatattccat agtcttatcg tctactggaa agattccatt ttttgctcct
     3181 gcttctattg ccatattaca aatagtaaat ctatcatcca tagataagta ttctactcca
     3241 tctccacaaa attccatcga cttgtaaagt gctccatcaa cacctatctc ccctattata
     3301 tgaagtatta tatctttacc acttatccat ttatttggtt tattcttcaa aacaaatttt
     3361 attgctccag gaaccttaaa ccaacatttt cctgtagcca tacctgctcc catatcagtt
     3421 gaacctacac cagtagaaaa tgctcctaat gctccatatg tgcaagtatg agagtcagca
     3481 cctataatta catctccagc agttactata cctttttcag gaagaagaac atgctctatt
     3541 cccatatctc ctacatcaaa aaaatttaca actccttttg attttgcgaa acttcttgta
     3601 aatttacatt gttctgcact ctttatatct ttattaggtg taaagtggtc taaaaccatc
     3661 actactttag tcttatcata aacatcttca attcctaatt tttcaaattc tctaatggct
     3721 actggtgatg ttatatcatt acctaaaact acatctaaat ctgcttcgat taattgccct
     3781 ttcttaactt catttaattt agcatgtttg gctaatattt tctgcgtcat agtcatcccc
     3841 attttttatt tcctcctcaa tataactttt atttattgca ttcataagtg cattaatagc
     3901 tgctgtattt atgttttccg atatacttac accaaaatag acttcattat tgtgctctat
     3961 tcctacataa gctacccctc ttgaatgtga cccttcctct aatgcatgtt cccagtaata
     4021 tctaaattta taatctttca tgccacattg ctttagtgca ttattaaatg aatctacagg
     4081 tccatttcct ataccaacaa tcctttgttc atttcccata taacttattc ttgcagtcat
     4141 ctcaatcatg ttagtatcat tagaatcatc attttcatag tttaattcat ccattgattt
     4201 tattttatac ttcttaactt tataagggct ctcaacttca atatattctt tcttaaataa
     4261 attaaatatt gcttcactac taagttcttc cccaattcta tcagattcca ttttgactac
     4321 atttccaaaa tcagaatgca tattcttagg tatcataaat ccataatctg tttccattat
     4381 ataaacagct cctccttttc cagattggct atttatcctt ataatttctt tgtattctct
     4441 tccaatatca tgagggtcta ttggtaaata tggaacttcc cagtaatcat tatctctgtt
     4501 tttcattgct atcatgcctt ttctaatagc atcttgatgt gaacctgaaa aagcacaatg
     4561 tacaagatta cctgcatatg gatgtctatc atgtaccata agttttgtac agtcttcata
     4621 tataccaatt atcttatcta tattgctaaa atctagctct gggtctattc cttgtgtata
     4681 aagattaagt cccacattta ctatatccat atttccagtt ctttcaccat ttccaaatag
     4741 tgttccttca agtctatcgg caccagccaa taatccaagt tcacttgcag ccgtacaagt
     4801 tcctctatca ttgtgagtat gcaaacttag tataatagaa tccctacaac ttatattttt
     4861 acaaaaccat tctatttggt ctgcatatac gtttggtgtt gccatttcca ctgttgatgg
     4921 aagatttatt attacttttt tttgaggagt tggtttccaa acatctatca ctgcctcaca
     4981 tatttcaagt gcataatcca tctctgttcc tgtaaaactc tctggtgaat attcaaaagt
     5041 aaattctgtt tctggatatt tttttacttc ttcattaaat aattttgctc cttcaactgc
     5101 tatatctatt atttcttgtt tactcatatt aaaaaccaca tctctttgaa gaacagatgt
     5161 agagttatat aaatgtataa ttgctttttt acatcccttt attgattcaa atgttttttc
     5221 tataagatga gccctagatt gtgtaagtac ttgtatagtt acatcatctg gaatcatatt
     5281 ctcatctatt aattttctta aaaatgtata ctctgtattt gatgctgatg gaaatcctac
     5341 ctctatttct ttaaatcctg tatcaataag cattttgaac attctgactt tttcatttac
     5401 actcataggc gttggcagtg actgatttcc gtctcttaaa tcgacactac accaaattgg
     5461 agccttaaat atttcattat ctggccattt acgatttact atttgcattt tatcatattt
     5521 tttatacttt ccacacttca tgttatttcc ccctttttct gttttttgta ttcagtatac
     5581 cttatatcga cgcaatcctg cacacttcat aaggataaat gtcaatttta tcattagaat
     5641 aaaaaaaacc tcatctctaa taaaattaga gacgaggttt tgctcgcggt accactctat
     5701 ttagctttct aaaaagctcc cttagtaata gccaatacaa taattataat gactatattt
     5761 cctataacgt ggaattactc cgattattct aagatttaaa tcttagaaaa cagctcctag
     5821 acaagttcag aactatcaac tactaaatca caccatcctt tagctctctg aaagtttcat
     5881 tgttcttact acttctattc atcacttttt taatcattta aattttctaa atattttgat
     5941 ttaatagtta ttatatacac attaaaatgt attgtcaaca aaaaaaataa ttatctcaat
     6001 tttttatttt tgataagcaa ttctataaaa catgctaact attgaaaaca gtatgatatt
     6061 atgccttaaa ctttttcatc ttttcatcta tgatattcaa taattttttt tcatcttcca
     6121 aactcaatgc ccttaatcta attttataat tagattcgtc agtgtatata tttaatatat
     6181 tttttactac ttctattttt tctattatct tataattaaa cttttgactt tgtttagatt
     6241 ttatactgaa tatacattga ttatttatta atattgaatg attatcgaga gtaatatata
     6301 cttttccctc atatttattt gaaaaatcac gaccttgttt aaatagaaaa actgctgtta
     6361 ttatacataa aatatataat attgtcgttg aatatataaa aattgtagct aaaattataa
     6421 gtgctaaaac catatatata gtcattcctt ttttaaaata accattgtca taataattca
     6481 tatagataaa cttattttta ctcaaatttt ttcactccca agattctaaa aatttatatc
     6541 aaaaaattct ataatttcat cttcatgata atttatgact aattcatctg gaaaatctac
     6601 tgcttctaaa actttttctg cattttcaaa ttctcctata gaataacata tatgagagtc
     6661 agtaccaaga attactcttg taccatatgt tttacacaat gtcaacatat gacttacatt
     6721 ttcccaagta cccgttctat gagagtttga acttaatgat gaattattta tttctaaaag
     6781 gatattttta tctttagctt tttttactat aggttcataa tctaaaggat acctactgtc
     6841 atctggatgt ccaattattt ttaccttagg tttatccata acttttaaaa tagcatttgt
     6901 attttcttct tttgtaccag aagctataca aggtctatgc aaacttgcga ttatataatc
     6961 caaatgttgc aacatatctt cttgaacatc taaattacca ctataatcca ttatatttcc
     7021 ttctattccc ctaagaatct ttacaccttg cacttcacgt ggaagcaaat gcaaattata
     7081 aaaatagaat ggatgtggtc ctcctggcat attaggtccg tggtctgata ttcctaagta
     7141 ttttatattc ttcttactcg cctcttcgac attttccttg aaagtactat gtgcatgtcc
     7201 acttattaga gtgtgacaat gtacatccat aatagacttt ttcattaaat ttcctcctaa
     7261 tattttacat aaattcgtga aaatagctaa agggctattt caaaactaaa gctgtcataa
     7321 tagacagtgt aacgttttaa aacagcccca ttttcaatta ttttacactt ctaaatcttt
     7381 aaatttatct ttaaataatt ctccaatact tcctaaagat tcctctactt ctaggtattc
     7441 tgttatatcc tcttctggct ctctagttgc ttcttttatt gaaaccaaca ttcttttagt
     7501 ctttggttta aaatcaagaa tcttaacttt aacctcatct ccaatattaa caacattagt
     7561 aactttagcc actctagtat cactcaattc agatattggt aaatacgcat ctacaccttc
     7621 tttaatttga acaaaagccc ctttttctat tattctaaga actttagcat tgacaacatc
     7681 atcaatttgt acttcttttg ctattaaatc ccaagggtca ttatttatgt cttttaatgc
     7741 caaggcaatt tttttagtct ctttatttac atccaacaca taaacttcta cttcttgtcc
     7801 ctctgaaaca acatcttcaa cactttcaac tcttgtccaa gctaaattat ttatatgtgc
     7861 taatccttca atcccaccaa tatccacaaa tgcaccataa ggcattatct ttgtcacctt
     7921 accatctctt ttttgtccaa cttcaagaga attaaataag tcttctttag ctgctttgat
     7981 acgagctttt tcttcttctc tttcttgctt aattcttgct ctttcagctt ctttttctgc
     8041 cttaatttga gctcttcttt cttctctctc tttatttata cgctcttgta atacatctct
     8101 atgagatgct acaagtctat tttttctaac atccaattct tttatataaa cttctaagtt
     8161 aagaccaaca aatttagatg tatctgtaat aaattttgta tcaagttgag aaattggtat
     8221 aaaaaatgta tatgtattgt aattagcaaa tacaccttta tctatattct tttcaacatt
     8281 tacagttatt attctatgtt catcataagc cttttgtaac tcggcaaaat catttctttt
     8341 gtcaagttgt aatttagata aagttattgt accatctttt tgagatactt ttgttattac
     8401 agcagttatt tcatcaccta tgtggtatat atcttctata tattgatttt tttctatgtt
     8461 caattcactt ataggtatta ttccatcaaa cccatagtct aatcctaatt gtacttcatc
     8521 atttctcact gcagttattt ttccagttgt caattctcca actttcactt tgctgaatac
     8581 ttgttcttgc tggtcaagta attcttgcat tgttaaatca ttttccatta taaacatcct
     8641 ttcctcttat tgattatcat atctgtaaat attataccat taatattgca aatacttaca
     8701 tttttcttac tataattttt aaaataaatt caacttcata tatttataca ttatagaaaa
     8761 tatcttatta aattaaaata caaattctaa tttttatcta ataaaatatt ttcataaaaa
     8821 atttatattg tatatcttat tcttttattg ctttaggttt tgatagaaaa catttataaa
     8881 atataaagaa agaaattgct gttatagtag cagctgttat atctgcaact ggctctgcta
     8941 aaattactgc aaaaagtttt tcattaaaga atgttgggag tataaatatt aaaggtatta
     9001 aaagtacaat ctttctaagt agagctaaaa ccaaagatat tgttgctttt ccaagtgcta
     9061 aaaatgtctg ttgacaagct atttgaatcc caaacataaa agcaccagca aaatatattt
     9121 ttatactcca actagtcata ctaagtaact gcggattctt attaaatata ctaacaaaaa
     9181 atgcaggaaa tatcattaat aaaagccata aaatagtaga atatgtaaaa catgacaata
     9241 aacacaactt aaatgtcttt tttactctat caagttgacc tgaaccataa ttataactta
     9301 ttattggttg tgctccttgt gtaaccccca tattaggaag cataagaatt tgcattatac
     9361 tgctcattat ggccattgaa cctactgcta aatctcctcc atacatttgt aatttactat
     9421 ttaaggctat aagtactaaa ctttctgtag attgcattat aaatggagag attcccaagc
     9481 caagcactgg taagatgata cttgcttttg gtatcatata cttctttttt attttaagta
     9541 tacttttctt tccaaagaga aacataagta cccaaatagc agaaacgcct tgtgcaatta
     9601 tagtagctaa tgcagctcct tttacaccca tattaaagcc aaatataaaa atcgggtcaa
     9661 gtattatgtt tattaaagca cctatagcaa ctgtcatcat tccagttgta gcaaaccctt
     9721 gggtatttat aaaagtattc atacccattg aaatctgaac aaacactgta cctattaaat
     9781 aaatatttaa atagtccatt gaatatctaa ttgtagattc acttgctcca aacatccaaa
     9841 gtaaaggctc ttttccaatc ttaaaaccta tagtcaaaag tattgctaaa atcaccagta
     9901 cagaaaaact gttactcatt attttctctg cctcatcatt gttttgctca cccattttta
     9961 tagcagctaa tggacctcct cccataccga ttaaataact acatgcagtt attataatta
    10021 ttattggaaa ggccactcca acaccagcca tagcaacttc tccattttcc attctaccaa
    10081 taaaaatcct atcgactatg ttgtataaaa catttacaat ttgtgcaata atagcaggtg
    10141 tagcaagttt aaataataat ttacccacac tttcactgcc taagttagtg tttgaatttt
    10201 ccattttaaa acctcctcaa tccaataatt aaaatgtatc actaaaattt tattctatat
    10261 aaaaatttca ttttatcagc agacaaattt agagtacttt ccctacaagt aatactatac
    10321 tatatttctt ttgccatagt aaacatttta gaactaactg aatttaaata ctttatctca
    10381 ttttttattt attattaaaa atttttcaca tgtactcata aaaaaactat ccaagtatat
    10441 tacttagata gttttatatt atatgtaaag aaagagctga aactataacc cctgataaca
    10501 aattgccaag aaatactccc ataaaagcat cttttattct catttttaat atggaagcta
    10561 tagcagatgc agtccatgtt cctgtagttg gcagtggtat acctacaaat agtattatac
    10621 caattatcga aacacttttt aatttcttca ttcttgagtt tatttttcta tcaattacat
    10681 cagcaatccc tttaaatagt ttcttccctc ttaaaaattg taatacatgt ctgaatgtca
    10741 atatcaaggg aatcgatacc aatgtagaac ctattacact aaatacataa acccatatag
    10801 gatttaagcc cattgcaata cctataggaa tggctcccct caattctgtt acaggaacca
    10861 tagataaaat taatatgtgt aaatatccca aactattccc tcctattcta agtgacatta
    10921 agttatgaat ttatttgctc tataacctca ccatcctttt tactaactaa aaatgcattt
    10981 ttagtcaatg aaagcattgg taaatcactc ttagagtctg aatatgcata tgaattttca
    11041 taatcaatct ctatcccaag tttacctaat acagccttta ttctttttac tttttcaatt
    11101 cccttacagt tttctccaat gaattgattt ttatatcttg aattttcata aaaaaactcc
    11161 gtgcctataa ccttgtctgc aagaccataa tacttaaaat atttcatata tgcatatgga
    11221 gatgcagtta tcataattat aacattatct tcttctttat ttttgtaaat gacctttttc
    11281 atagattcgt taattttttt cattatgcaa tcatcaaaaa acttttttaa atcttcttca
    11341 ctaaaatcta ctattggata aaagattgcc tcttttgcct tcttcaaggg tatcattcta
    11401 attaaataca taaatagaat aaaaataatg tatggcaact ttataatagt tttaaaggtt
    11461 ttatttttta aagagtaaat aaaaaaatct atcatgctat cagtatttat aacagtataa
    11521 tctacatcaa gtaataatac actttttttc ataagtattt ccccatccta tcactaaaaa
    11581 tatcactaaa aaatcaatat tattaaacat gtaattatcc ataagattac gtttattttt
    11641 aaagcattat cttttaggac aatatcagta ggattatttt catttgtagt gttaattata
    11701 taattatatc taagtacacc ataaactaca aatattgttg taaatatcat atgtggcttt
    11761 tctggattac ttgtagaata caatgaataa catacaattg tagaacttaa tataactatc
    11821 atcatttgat ttagattttc tatgtcataa tcttccaata tttttctatg ttcaactgca
    11881 tcatctctta gagtttctat ttctttttta cgttttccaa gagctaagta cagagataag
    11941 aaaaatgtac ataaaattat ccaatttgat aaactaacac ttatggctac acatcctgca
    12001 taaaccctaa gtataaaacc aagagatatt gaaaacacat ctaatagtat tatattcttt
    12061 agtttaagag aatataatat attgtttatc aaatagagac taagaattat agaaagatta
    12121 aaactaacaa ctgttgataa acagactgaa attaaagcta atactacaaa tagtatatta
    12181 gcactttttt tgcttattct tccacttgcc actggtctat tacatttttt aggatgtttt
    12241 ttatctttat ccatgtctat agcatcattc agtgcatata ctgatgatga cattaggcaa
    12301 aaacacacaa acgcaataaa cgtatttaaa aataaattta tatttagtat gttgtttgaa
    12361 aaaattatag ctgaaaatac aaagaaattc tttatatatt gctttattct cattaacttt
    12421 atataatctg aaattttagt aagaagcctt atacttgtat tggtctgttt cataaactta
    12481 ctaccctttc aatattattt tttaaacagg atatgatttt atccctatgt ttaaaatttc
    12541 tataaatcca ttgacattac tgattactat agtaaccaat aacagcgata gaaatatatt
    12601 atacatattc ttttcatttt ttctaagcgc tttcgtaaag taagccaata aaattataac
    12661 tgcaaaacta aaatttatag ccataatact tgaattgact agattatatc ctactatacc
    12721 atgtaaagtt agattgaata taattattcc catacatagc ttaggaactc ttttttctga
    12781 attttcaata actgataaaa cacaaaaaca taaagctaat aatgtaagaa ttactggtat
    12841 tgtagcaact tctccatttt gcaaaaataa ccctttttta atacttgctc caggaaaata
    12901 aaaaaccgaa tacaataatc tctctataat cattgcaatc ttttccaaaa ttggttctcc
    12961 acttataaat ttcgtatcat actgtattac atttccaagg ttcataaaac tctcataaga
    13021 cttcgttgaa actacacaaa tatatgccat taggataaat gtaattaaat gttttaacat
    13081 ttttcctatt tttaatttaa actcaaatat catattaaaa aaatacaaat atatattact
    13141 aatagttatt ccaaatagag gaatagctgc taattctact aaataagaat tttttccttt
    13201 catcttattt gcaataacta tgaaaaatat taatgaaaat tggctatata taaatctctc
    13261 tacatttaaa gtcataaata actgtggaaa agaaaatatc attatcatag taagtaaaat
    13321 taaagttaat ctctgcattt ttatcttttt aatatgatta aagactaaag ttattgacat
    13381 agcactagtt attatttgta gacaaattag tccaaaccca taggcactat taaaatctgt
    13441 tgtcccagga tttgctattg aagtacaaaa taggtatatt ggatatgcaa aaattgatat
    13501 aattgctgaa aacaatatgt gcttactatt gtcttgactt atagcaaata catttaaatt
    13561 gaataaaacc cctgtatctg tatctaacaa tacatcataa gtattgttta aattataaaa
    13621 tatagtagtc ttagaaaaaa atatcttagt tattattaag taagttatta caactaatat
    13681 aaacaaaaac atctcgtttt tatattttaa tattttactc atcaatatat caccatccat
    13741 tcattatata ggatttgctg acacctacaa tttattcctt atatttaata gccatcttca
    13801 taatgttctt acttgtttta ttgtaattga ataactcttt atttacaacc acaatattta
    13861 ctttattgat gttataatca gtcaagtatt gtttatataa catagattag tgttgtataa
    13921 aatgagaatt tgtaagcaat attaatgtaa aatatttgaa aaactttata taaaaatata
    13981 caatgttgct tatggaatta aactataaca aattaaagca taatttaagg agacaaaatt
    14041 ataatctgtc tccttaaata ttaaaactat attttaaaac attactaaat actatacaaa
    14101 tttcaaatat agtataaaat taattagact ttaacactat tagctccatc ttcttcccat
    14161 tttttaattt cttttaatct atctattata ggtaaatgct gagtacattc aacttcacat
    14221 tttccacaag atatacattc tttagctttt gccttactat tcattgtgta attccaatgt
    14281 cctaaaccat aaactaactt tgtcatttct tcatcactct ttttaaacat ctgcttttca
    14341 ttataaaaaa gcatataggc tggggtatta ataccttttg gacatacttt acaataacca
    14401 caacctgtac atatttcgtt catattctta tttaatctag tctcaatatc atgtatatcc
    14461 tcatctgaat aaattctatt ttcgtctgca attttacatg catcatctat atcttgtttt
    14521 ttattaaacc ctatcaaaga tatacttatt tgtgaaattc ctatgttgaa tcttaaagct
    14581 gattctatag tactttcgcc atcttttgat agaaaagaaa gttctttatt atactttgga
    14641 atagttccac cacttaatgg attcattgcc acaacaccat atccattatc aacagcatat
    14701 ttggcacctt ttagcctata tggaaagttt aatatattta ttcccatagt tacaccttca
    14761 aacttatttt cacttagaat atctataacc tcatctcctg gttgatgaga tgaaaatact
    14821 atatggtcta tcaatccttc ttctttacat ttcaataatc cttcatattg acctccaggt
    14881 ctcattgcta gttcgtaatg ttccatcttt ctaatattcc aaacatgata aaaatttatt
    14941 ttagatacgc ctaatcgttc tattgatttt tttacagcct ctatagcttt ttctgatgta
    15001 tcacatgctt ttggcttttc tttagttgat acataaaaat cggtcttacc ttcctttatc
    15061 atttgtctaa aggctagtcc aaatatatct tcacttctgt catcacaata ccctggcgct
    15121 gtatcaaagt aattaatacc tttttcatac gcatatttga ctaaatcagc attttcttga
    15181 ttactttttt ctaaatcaaa ccttaatcct ccatagccaa ctactgaaac cattttccct
    15241 gtctttccat attcaacgta tctcattgta aattcctcct tagatatatt aagacttaat
    15301 ttctttatag aaaatattat accataaata atttttataa attatttatg gtataatatt
    15361 ttttttataa attatatttt tttataactt gtattttata gctaagttaa aaactataaa
    15421 aaggttcaat atggactatt acttgagcat tttcattaat ttcttcttgt atttgtttct
    15481 caattttatg tgttaaatca tgagattgct ctacgcttat aaatgggtct accattacat
    15541 gcatgtcaat ataaatagaa cttttgctac ctctacttct gatattgtga acatccctta
    15601 cctcattaaa ttcaaacaca atttctttta tataatcctc atctacagcc actctatcga
    15661 ccaaaattcc aatagatggc ctaaatattc cataagccga ataaattatg aatgcagaaa
    15721 taataatagg aactatagat tctattatta ctggaaatcc taacttaaca ccaactaaag
    15781 taaccaatac acctagagac acaaatatat cacttcttgt atgcaatgaa tccgaaatta
    15841 aaacataact atttagttta gtcccaattc tatattcata catgcataca aaaatattta
    15901 taaaaagtgt aataattaaa gcaattaaac tttctatagt tatagcaggt acaactggat
    15961 tagctattct tagcactgca ctaagaatta tcttaattgc tataacaaac aacataccac
    16021 ttataaataa actggttata atttcaaact ttttatgtcc ataaggatga tttttatctt
    16081 ttggtttaga tgcaaagaaa atacctataa gccccactat attagatgct ccatctgaca
    16141 aagaatgaaa tccgtctgct gtcatactat agctttttat ttgattacca ataatgattt
    16201 ttaataatgc tactgcaaaa ttagcaaata aaattatcca caatacttgc ttcactttct
    16261 tatagttatc cataacaaat tccccctccc ttcgattcaa taaagaaagc tatctatcaa
    16321 tatcaatcac ccagataata aaatcgtata taagcacatt tactatattt atattcaaaa
    16381 ttggttgtac ttgttcattc tatttgaaac ttaattataa ataaaaatcg taggtatggt
    16441 tttggtatac ataaaaataa gagactgtct caaaataaag ataagcttct tttttattgt
    16501 tgaaatgata aaatatattt gatttcatat aaaaaagagt gcctcatgaa ctaaaaagtt
    16561 cattttgaga cactccctta aatttttgat ataaactatt aattttttat actaagcctt
    16621 ctttaactaa gaatgaatga gcaacttctt ctggtgattt accaagttca tccacttgat
    16681 agttaagttc tctcatagtt tcttcattta tttttcctga aagcatattc ataacttttt
    16741 ctaactcagg atatttcttc aaagtatctt ctcttactaa tggtgctgca taatatggta
    16801 caaagaaatt tttatcgtcc tctaatatct taagattaaa ctttttaata agaccatcag
    16861 ttaaaaatgc atctataacc tgagattcat tattatctaa agctgtatat cttaaacttc
    16921 cattcattgc ttttacatct ttgaatttta aaccataatc tctagaaagc cctacaagac
    16981 catcttctct attttcaaac tccaaagttg gtgagaatgt aaattcttta ccatatttag
    17041 tcaaatcaga aatagtattt attccatact tttcagcagt ttcaggcatc atagctaatg
    17101 tgtaagtatt attaaatcca agagggtcaa gtaaagttaa ctgattttct ttttccatag
    17161 tatcttttac aacattatat gcttcatcag catctttaat cggagcatgt ttcattacat
    17221 ttaccaaaag tgtacctgta tagtcaacat acatgtctaa ctcaccagat ttaattgcat
    17281 taaacgcaac agatgaacca cctagattta aattcttctt aactttaaga ttcgtatttt
    17341 tttctactaa ttcagcataa acattaccaa gtataagttg ttctgtataa tctttagaac
    17401 caatagttat tgtatctttt ttacttgaaa aactagaact aaaaacaacg aacaacattg
    17461 aaacaacaac cactacagat attactttaa gtgctatata atttttctta ggtgcttttg
    17521 gatttaatcc ttttggagta actgcaactt caattttact aaataaataa tcaactaaca
    17581 gtgcaattat acatgatggg attgcccctg ctaaaatcat attattattt acagtttgaa
    17641 cccctgaaaa tactaaatat cctaaaccac cagcacctat aaatgctgca agagtcatca
    17701 aaccaacagc tgtaactgca gatattctaa ctccacccat tattatagga agtgctaaag
    17761 ggaattgtat tttaaataat gtctgatttc ttgtaagacc aataccttta gctgattcta
    17821 atactactgg gtcaatactt gttataccta tatacgtatt ttttacaatt ggtagtaatg
    17881 aataaaccac taccataaat atggctggtt tacttcctat gccaagtata ggtacaagaa
    17941 gacccaaaag tgccatagac ggaactgctt ggactaagtt tacaaatcca agtacaaact
    18001 ttctaagaga tgagattctt gaaataatta ttccaagagg aacaccaact attatagcta
    18061 ttaaaataga tgtaacagtt agactcatat gttgtattaa aagctctata atcttatctt
    18121 tttgtaatag tataaagtta aaaaaattag ccaagaacac tcacctccat ttctaagaat
    18181 tgttcactta aaacagaaag taaactactt ctagtaataa gccctaccag tttattttca
    18241 tcagaaataa ccggaatata tccaaccgaa ttacgattca ttacatttag tatttctact
    18301 aaattatcac cttcatttac atgcaaaggc tcactcgaca taatatcagc aagtaatatt
    18361 gacttatcat caatatcttt catatctttt acagtaacaa taccttttaa tgtttttgct
    18421 ctatctataa ttagtaagct atcaacctta ctcgttctca taatttctat tccttgagtt
    18481 acagttctag tggaattaac agcaatagga ttttttatca taatatctct tgcttttata
    18541 tattctggat tatcccaaac tctatcttct ccgataaaat cttttacaaa gtcatttgca
    18601 ggctttctaa gtatattttc gggagtatca tattgtgcta ttcttccatc cttcataata
    18661 caaattttat cagctatctt taaagcctca tccatatcat gcgttacaaa tattatagtt
    18721 tttttcaatt catcttgaag agaaaataat tgttcttgta aagatgttct cgttattggg
    18781 tctaaagcac taaaaggctc atccatcaat attatttcag catcagtagc aatggctctt
    18841 gcaacaccaa ttctttgttg ctgtccacca ctaagttctg aaggatactt attcaaaaat
    18901 tcatcactat caagtcctac catctcaagt agttgcaacg ttcttttttc aatttcttca
    18961 acggattttt ccttttttag gcgtggaatt agctctatat tttcttttat tgtaagatga
    19021 gggaataggc ctgtgttctg tataacatat cctatttttc ttctaagctc tatttcattt
    19081 tcctgagaaa ttggtttgcc attaatatat atctcaccag atgtaggttt tattaatttg
    19141 tttataagct tcaaagtagt agtctttcca caaccacttg aaccaatcaa aactaccaat
    19201 gtacctgttt ctacaactag agaaatatca tctaatataa cattatttcc tatttttttt
    19261 gttacatttc ttatctctat cataatttat catccccttt ttcgaacaag caaccttctc
    19321 caatattata agttgttttt ataattatat catactattt tatttatgta aacaaagtac
    19381 gatttttagg tcactatttg tctgaatatt gctacaaata taaagtattt atatatagta
    19441 tataatgtca aaaaacaaaa agtataaaaa tattcataaa ataacactag cctcaattat
    19501 atagtattaa agctagtgtt atttcattta aacaaaactc acatttgaat actatccatg
    19561 tattcaaata atgtaatatc tttataagtt tcttttttat cacttaagtt tgatattgta
    19621 actcccaata gcctaatttg ttttccatta acctcaacat ttctcaacaa attatctaca
    19681 ccacttctta tatcattata ttcgtcaata tagtgttcta aactaaggct tctagttatc
    19741 tttgtaaagt cctcatattt aatttttaat gttaatgttt ttccaaactt ctcagagctt
    19801 tttaatctat gacatacttc ttcacaaagt tcatcaagaa tgttgcgtgt ttcttcttca
    19861 tcaatatcca aattatgact taatgtagtc tcagccccaa cagattttct aaccctattt
    19921 ggttccactg gtctatcgtc tattcctcta gcaaatttat ataattcata acctcttttt
    19981 ttgaatatat tttcaagttc aaataaattt aaacacctta aatcatatcc agtttttata
    20041 cctaaatttt taagagtatt tgaagtaact tttccaacac caaaaaattt attcacaggt
    20101 aatttatcta aaaagtcctg ggcattttct tcggttatta cagttaaccc atttggcttt
    20161 cttaagtctg atgcaatctt agcaagaaac ttattgtatg acacaccagc tgaagaagta
    20221 agaccaactt ctctaaatat atcttttttt atttgctttg ctatctcaat tgatgaatca
    20281 atattttttt tattttttgt tacatctaag taagcttcat ctaaagataa tggttcaact
    20341 aaatccgtgt atctataaaa tatatctctt atttgctctg acacactctt ataaacatca
    20401 aatctaggtc ttacaaaaac tgcatatgga cacctattgt aagctacagc tgatggcata
    20461 gctgaatgga taccaaattt tctagcttca taagaacacg ttgcaaccac acctcggctt
    20521 tgtggatttc caccgacaat aacaggtttt ccttttaatt ttttattatc tctttgttct
    20581 atagatgcat aaaaagcgtc catatctata tgaattattt ttctataatg tttcattatt
    20641 atcacctttt aaagtataaa tagattaatt ttatttatat tactttttaa ttataccaaa
    20701 cttatgtttc tttttggtat tttttcatta ttttctttat atattcatat tttccataaa
    20761 taaaaccatc tataatccat taacttcaat ataatttata aaaaatcctt aaaaacactt
    20821 gcaaaaacta tataaaagct ttacaatagg tattccaagg aactaaattt aaaattcctt
    20881 atggataaca gtatatatat ttaatttatg ggatgtttta aaaacaaaag actgtcttat
    20941 acaagacagc ctactgattt tattataatt gtaatggact gctcaaacta ttactttaaa
    21001 acagcccata tttttttata taattttaac tatagtaaag attttgtgaa ggatattctg
    21061 ggtcacaagt tacatctata ccaagctttc taaatgtttg ttcatcatct ctatttaata
    21121 tagtagtaga atgagcttga caccctttta ataatgctaa cttttccata gcaaactgtg
    21181 cagttggatt agttacagca caaatactaa gtgcagttaa cacctcttgg caactaagtg
    21241 aaacatttct actagctaaa gtctttgttt ttaagtttat gataggttct aatattacag
    21301 gtgatattaa gtgcatatca tcagatatat tggctaaatg tttaatggca tttaatacta
    21361 ctgctgctgt tccattcatt aaatcagaac ccttaccagt taatattgta ccatcttcta
    21421 attctaatgc aactacagga caagtatcat tcttgtcggc actttctttt aatttattac
    21481 tgtaatttct agcaggtaat acaacatttc tatcttctgg ctttaagtta agctcttcca
    21541 taatcatttt cattctatca taagcgcctt tatcaacttg tcccttttta tactcacagg
    21601 cagttttaaa gtatcttctt attatttctt ctatagaagc ttttcttatt acttcatcat
    21661 ctattattcc aaagccaact ctattaacac ccatatcagt tggagattgg aaaattgatt
    21721 cttttccagt tatcttttct attatttttt taagcactgg aaataattcc aaatctctat
    21781 tgtagtttac tgacatttca ccatacgttt caaggtggaa tgaatctatc atattcacat
    21841 cttttaaatc aactgtagct gcttcataag ctatattcaa aggatgtttt acaggtacat
    21901 tccaaactgg gaatgtctca aacttagaat atccaactac attacctctt ttattttcat
    21961 gatacaactg acttagacaa gtaccaagtt ttccactatt aggtcctggt gctgtgacta
    22021 ctactattgg ctttgtagtt tctatatatt catttgctcc atatccctca tcactaacta
    22081 tagtctcaac atctgacgga tatccctttg ttggataatg cttataaact ttaattcctc
    22141 tacgttctaa tttatttata aatacagttg tagcaggttg tccttcaaat ctagtaatta
    22201 ctacactatt tacatctagt tcataacctc ttaaatcatc tattaatctt aaaacttcca
    22261 tatcataagt gataccaaag tctcctctta ttttgtttct ttctatatct cctgcataga
    22321 cacaaattac aacttcaact ttttctttca tatgttgtaa tacttttatc tttgcatttt
    22381 catcaaatcc tggaagtact ctttttgcat gaaggtctcc catcaatttt cctccaaact
    22441 ctaaataaag tttgtcaaaa ttatttactc tttctaagat gtatttagac tgctcttcta
    22501 aatatttttt gtggtcaaat cctactttca tcttaacacc tcactaaatt aaatttcttg
    22561 ttgataacag tatatttata tatatttttt tagtaaaaca tcttataaaa aaatgttaat
    22621 actttttcac tcaaagtaat attatacaat taagattaat ttttttcaag atagttttat
    22681 ggtaaa
//
LOCUS       DAMJYN010000061        22386 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.062, whole genome shotgun sequence.
ACCESSION   DAMJYN010000061 DAMJYN010000000
VERSION     DAMJYN010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22386)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22386)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22386
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.062"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(432..1538)
                     /locus_tag="PC466_002558"
     CDS             complement(432..1538)
                     /locus_tag="PC466_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HDF2769925.1"
                     /translation="MLDKNRLINNFMDMVRIDSPSNQELEMSKWLVNYLKERNIDAII
                     DDAGEKYGGNTGNVIAYIKGEEGSRPLCLCAHMDQVQPCLGVKPILDGNVVRSDGTTT
                     LGADDKAGIAAILEALEHVTTEKIPHRDIYLCFTICEEAGMHGVKNFNPDNLPCKDMV
                     ILDSGGAIGSIAYKAPAQQSIKISFHGKKAHAGIEPEKGLNAILVASHAISNMHIGRI
                     DPLTTSNIGKIEGGGATNIVTDKVTLTAEIRSHIPETLEYELNHMEKCCKDAASKFNT
                     TYTFEHSMSYPSFELSRDSHVFKLSEEAIRQVGVVPNPMVIGGGSDANILANLGYNCA
                     ILSLGMYDVHTVNEYVNIDELYDTAKIVYHMIKL"
     gene            complement(1573..3114)
                     /locus_tag="PC466_002559"
     CDS             complement(1573..3114)
                     /locus_tag="PC466_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbgT family transporter"
                     /protein_id="HDF2769926.1"
                     /translation="MNDNVVKKKNFFDRTLNRIETVGNKLPDPVTIFLGLCVLLLILS
                     SLVGSMGISVVHPGTGETITAVNLLTVEQLQILLGNIVSNFQGFAPLGLVLVTMIGAG
                     VCDKTGLMTATIKASVSKIPETRVTLVVMTIGMLANIASDAGTILFPPLAALVYLGVG
                     RHPLIGLFSGYAAVCLGFAANIMISVNDILAASFTVPAAQMIDSGFQANATMNLFFMI
                     ASTFVLILLATWVTEKIVAPRFGKYEGNAELDVDGSLSDVEKKGLKKAGISILIYVAI
                     IVALSVIGKKPFLADPETGDLLSNNAPLMKGMVPIIALAFFIPGVVYGKTIGKIKKDK
                     DVVSIMASAMSDMGGYIILAFAASQFLQLFTNSNLGLILAVKGGEFLKSAGINGPLLL
                     IGFIILSCFINLFIGSASAKWAILAPIFVPMFMMVGYNPALTQMAYRIGDCITNPLSP
                     LFPYFPIILAFTRKYDKDAGMGTVIANMIPYSISFLIVWTILLILFMVFNIPLGPGIL
                     PSYSM"
     gene            complement(3476..4222)
                     /locus_tag="PC466_002560"
     CDS             complement(3476..4222)
                     /locus_tag="PC466_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF2769927.1"
                     /translation="MFNAGNRIINTWLYPIQDGFVLIDTGYENGFKHFKKRISKFNIK
                     IKDIRYIFLTHAHDDHVGFLNQILDESPNTKIVMHDKALEILYKGQNSFIGGCNSRTA
                     FLFCQIMKLFGKGEHSFSPLKQEFEKRCILVSDKNRKEIEKELNGKIIDTPGHTADSI
                     SLLIDDGVLFCGDSAMNGFPSTHKITIFAESKLEFIQSWKTIINTKPKMIYPGHGKPF
                     EYSKLEQNLIYVNKINLYPLHNSKDIHRFL"
     gene            complement(4434..5744)
                     /locus_tag="PC466_002561"
     CDS             complement(4434..5744)
                     /locus_tag="PC466_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2769928.1"
                     /translation="MNKEQLKSLVIKTIDENREKILKIGQGIYKNPEYGYKEFKTTEA
                     VSNFFEQELNLSVEKNIAVTGCKADANSSKKGPHISILGELDGISCKEHKDANEIGAS
                     HTCGHNIQIAGMLGAAVGLVKSGVLEHLDGKVSFMATPAEEFIELEYREQLKKEGKIT
                     YFGGKQELIKRGYFDDIDISMMFHASDLGEDKALVGPESNGFVGKKVKFIGKESHAGS
                     APHDGINALNAAMLAINNVNALRETFKESERVRFHPIITKGGDIVNVVPADVHMESYV
                     RARTINGMIDANERINKALMAGGMAVGADVEITEIPGYLPILRYKSLDNLFKNNLEDL
                     GLKGKVIDGGDFTGSFDFGDVSHIMPTLHPMIGGVKGALHTRDFEIVDEDLAYIIPAK
                     AMALTVVDLLFDNAKDAKDILDTFTPVMTKEEYLTFLEKHDKTL"
     gene            complement(5757..6227)
                     /locus_tag="PC466_002562"
     CDS             complement(5757..6227)
                     /locus_tag="PC466_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769929.1"
                     /translation="MFANLNLKKSSYQLLVMSVIGVIILIGQRISVGTSIVTALPGMV
                     MLILAAMAAMIIKDLFPKSIFPAFGFATIIGLLLSMPYSPTSEVFLTNTNNINFMAIT
                     TPLLAFAGISVGNKIEALKEMSWKIVIISLIVFTTIFFACASIAHIVLSIQGKI"
     gene            complement(6231..7082)
                     /locus_tag="PC466_002563"
     CDS             complement(6231..7082)
                     /locus_tag="PC466_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3100 domain-containing protein"
                     /protein_id="HDF2769930.1"
                     /translation="MEINKKHFIQVFLTCLILVVICEFIGQRTIAIGKASIVLFPMLY
                     AVIIGLIITPDLLGKKIKALKKVVGEKEINIAGEVVGIALVMLGIKYGTTVGPNIDKI
                     IQAGPAFIAQEFGHILAPIVALPLALMFGMKREAVGATASISREPSLGVISEKYGINS
                     PEGSGVLGTYLMGTVLGTIYFSVLGSISIYSGLHPYALGMACGVGSGSMMTAAAGSLS
                     TMVPPEMADTILAYAATSNMMSSITGIIFLVFVSLPFTNFMYKILEPKFSRNKKTKEI
                     KSTEGEC"
     gene            8007..8918
                     /locus_tag="PC466_002564"
     CDS             8007..8918
                     /locus_tag="PC466_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YafY family transcriptional regulator"
                     /protein_id="HDF2769931.1"
                     /translation="MKINRLTEIIVILLNKKLVTAKELADRFEVSTRTIYRDIETLSM
                     SGVPVYMTKGKGGGISLIEEYSIDKAILSKKDKESLIVALKTLQATKYPEINSVVNKI
                     GSIFGEQNFSNWIEIDFTEWGSNFNEDDKFTKIKEAILRRNTINFNYVNSLSSQTNRT
                     VEPLKLMYKSKTWYLYGFCKLKDDFRIFRISRIRNLSIKDEVFSRKIIEEVCLNDSKV
                     IKENTITLKLRFKEKMLFRVFDDFNKDLITKNEDDTYDVITEFPIGEWIYGYILSFGD
                     NVEVLEPKDVRDNVITRLRELSKIYSL"
     gene            9093..9590
                     /locus_tag="PC466_002565"
     CDS             9093..9590
                     /locus_tag="PC466_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HDF2769932.1"
                     /translation="MNYEIVEINEKIVIGISKETTNKDGQAVNAIGELWKKFMGKGIY
                     NAIKGKKNDKTIGLYTDYQGDFTSPYSFVACCEVNSNSDKEKNLEELNTNNTVGESII
                     SKVILAGKYAKFVIVGGQKEVGDFWFKFWQMDFDRTYISDFEEYQCNTFDTKKQEIHI
                     YIGIK"
     gene            10334..10696
                     /locus_tag="PC466_002566"
     CDS             10334..10696
                     /locus_tag="PC466_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HDF2769933.1"
                     /translation="MENKILIVDDAIFMRMIIKEALSKSGYNNLIEANDGEEACNIFK
                     YEKPDLMLLDITMPKKDGLEVLREIKKLDSSAKVVMCSAIGQENMIVEAIKLGALDFI
                     VKPFKTETLVKVVNNVLK"
     gene            10762..11379
                     /locus_tag="PC466_002567"
     CDS             10762..11379
                     /locus_tag="PC466_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheC"
                     /protein_id="HDF2769934.1"
                     /translation="MINYLELDDVHIDALREIGNIGSGNAITALASMINSNVEVLIPM
                     VKILEYNEATNLLGGPENKVVCILLDMKGDINGMFMFLLDESITQLMLSSLFNKEEAF
                     LDEIEAIEISAIKEIGNIMASSYVNAIASMLNMTISVSIPDICIDMVGAVLNVPMIRF
                     SDVGDKVLFIENKFKMSDNYFTSHILMIPEMSSLREILVRLGLEV"
     gene            11376..11861
                     /locus_tag="PC466_002568"
     CDS             11376..11861
                     /locus_tag="PC466_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheD"
                     /protein_id="HDF2769935.1"
                     /translation="MNREIVVNIADMKIAYRPNVLVTYALGSCVGVCLIDKVAGIGGM
                     LHVMLPYSKDAINIENKCKFADTGINELIKSMENIGANRIYIKAKIAGGAQMFLGSSN
                     SVIASIGHRNVEAVKKTLLGLNIPILAEDTGMNYGRTIRFYTETGELLVDSINKGKKK
                     L"
     gene            11904..12422
                     /locus_tag="PC466_002569"
     CDS             11904..12422
                     /locus_tag="PC466_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-binding chemotaxis protein CheW"
                     /protein_id="HDF2769936.1"
                     /translation="MRFPDDPYLDYGLIDEGIKYLKFKVDEQDFGVELEKVIEITGNQ
                     EIIFIPELPTYSKGIINLRGKIIPIIDMRLRLKKDELMTTNCMYIVVTEIKDLVVGFV
                     VDRVDDIVSLEKSKISPPPRVTIEYSDYFVSGVGELEGKIITLLDLEKLLTDKDEVLI
                     DELINGFDCTIM"
     gene            12558..13517
                     /locus_tag="PC466_002570"
     CDS             12558..13517
                     /locus_tag="PC466_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HDF2769937.1"
                     /translation="MKNKQQGTILVVDDSVLMCDLIDKTLTKDNFKVKKAFNAIEAKE
                     FIEEFIPDIILLDIILPDNSGFEFCKEVKSNTRTADIPIIFITSKNTDTDIVKGFGVG
                     AIDYMVKPFSMTELKARVIAHLEVKKSQDKLKKINNELESSLEKLNRLVVRDYLTGLY
                     NRRHIINQLMEQRRINKYSETSISLILGDIDDFKVINDTYGHEAGDFVLTVISSIIKK
                     NCRQIDTVSRWGGEEFLIMLTNTPIEGAKILSERIRKEIKEFDFNYKEHKIKCTITLG
                     VVEVNSNISLEENISLADKAMYEGKNLGKDCSVVSTMKGLKKI"
     gene            13543..15246
                     /locus_tag="PC466_002571"
     CDS             13543..15246
                     /locus_tag="PC466_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing protein"
                     /protein_id="HDF2769938.1"
                     /translation="MKREVKLSKLAIVLLIIIVLAVLAGIFSSISSYKAFEKVEKSIN
                     DMNNLRTQSQYIKDTTREISDVLRRYVFTGEKKNKDIYEKELYGKTRESALNKLEKIG
                     LTKSESNKILEAKEISDSLVPTEQSAIKAVESNDKSKAQSIIFGSDYINSQEKMDSLI
                     NEFQEDIVTRSNSKIVEVKKELQSLILRTIFILSLLIILTIIEYTVIKLKIVIPINRV
                     EKHFSRIASGDLRTSIDVEESKSEIGLLVSSVKKMQSMLLNYIDLIDSTLTSIAKGDL
                     RVEIDQEFIGDFKSIKISLESIINSFNGDFSEINLSAEQVASASEQVAAGAQALSQGA
                     TEQASSVEELASTINEISDGIKKCADSASLACEVSDQSASQVGFGSRCMDDMMTSMGE
                     ISEKSSEISKIIKTIDEIAFQTNILALNAAVEAARAGQYGRGFAVVADEVRSLAGKSA
                     KAAQNTAILIEEAIKTVENGVRIAKETANALDLVVNGVEKTTNYINGISSAVHSQEVA
                     ITQILSGIEQISIVVQMNSATAEESAAASEEMSAQAQILKELVEKFHLKESEVRESSW
                     V"
     gene            15503..17605
                     /locus_tag="PC466_002572"
     CDS             15503..17605
                     /locus_tag="PC466_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheA"
                     /protein_id="HDF2769939.1"
                     /translation="MRQMLDMFIFETSLLLEQLDEIMIQIEKEKVFTHNNINETFRIM
                     HTIKGSASMMGLDNISALAHSVEDLFYAIREGKIEVLDNDLLFDLVFQSLDFIRRDID
                     ELQSRGCISSDYSNFIEGIEEYVSTLELSSSMKSKDNANLESTDEKEAIDSNFEYKED
                     SDVVKIIFEQGCMMENVRAFMLVFELRDYCEFIDFYPKDVETNAESTEYIKSYGFYIQ
                     FVAKEDKAIVYKTIEDNLYVKEYINISKKEIEMKNTSNNDAVENKLKDNNKVSKSYQN
                     NYTEDEIQEDVLNEKTDMEKDSLSEENEHLPISKQSIMSVNLEKLDLLQNIVGEIVIM
                     ESMVVNSVNSTGVDIDNFNKATRQLHKLTDELQDIVMSMRMIQIAGVFQKMHRIVRDM
                     NKKLDKNVELITIGAETEVDKNVIDNLAEPFMHLIRNAMDHAIEPIEERIAKGKEEVG
                     KIVLSAENLGGEAVISISDDGRGIMRDKILAKAKEQGLLKHQINEYTDDEVNSLIMTP
                     GFSTKESITEFSGRGVGMDIVRKSIEKVGGSIEVKSKQDEGTTFTIKIPLTLSIVEGM
                     KFKVGDSLFTLPISSIRRTFKLTDLNQIITEGNKTELITIYGACIPIIRLHKIYNIQT
                     KVTNLMHGNMIIIENEHKAVCIFVDEIIGNQQVVVKPFPVYFNRFNIKNKGLSGCTIL
                     GDGSISLIIDADSIIEIY"
     gene            17618..18058
                     /locus_tag="PC466_002573"
     CDS             17618..18058
                     /locus_tag="PC466_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheW"
                     /protein_id="HDF2769940.1"
                     /translation="MAKDEIIKQVLTFYVNDVIYGIELENVIETIRFQSITYVPCLPT
                     YISGVINLRGRIIPVINMHIKYNLPKADYNERTCIIITKVDEYQVGIIVDKVVDVIHI
                     ENLNLLETTNSNNTNINKDIKEIAKVEDNSILILDIRKFLINSI"
     gene            18094..18897
                     /locus_tag="PC466_002574"
     CDS             18094..18897
                     /locus_tag="PC466_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-glutamate O-methyltransferase CheR"
                     /protein_id="HDF2769941.1"
                     /translation="MIKLTDEEFIVLVNHVKKEYGIDLSKKRALIEGRLYNTMIEKKL
                     SSFSQYMNLLFKDKTGNEAINLINRLSTNHTFFMREPQHFEFIQNSILPFWEENNKIR
                     NINIWSAGCSSGEEAYSIAMTLDDYFGYNKELWNIKIIATDISTNSLEKAKRGIYIES
                     NVNNVPELWKKKYFIDNKDGTFKICDKIRKSVIFKSFNLMNDFSYQHFDLIFCRNVMI
                     YFDLKTREELINKFYNATKKDSFLFVGHAEVINRSSTKYKYVKPAIYKR"
     gene            18937..19533
                     /locus_tag="PC466_002575"
     CDS             18937..19533
                     /locus_tag="PC466_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheB"
                     /protein_id="HDF2769942.1"
                     /translation="MERFNNMVIAIGASVGGTEAILEIIKDLPKSTPGIVVVQHMPAI
                     FTYMYAQRLDKQCIMNVREAKNNDRVEQGNVLIAPGGYQMKLCTDKQGYYVTCEKGER
                     ISGHCPSVDVLFDSVAEVAGKNSIGIILTGMGYDGANGLLKMKENGLFTIGQDENSCI
                     VYGMPMVAFDRGSVMLQLPLGEISNCLIRHINILKQKD"
     gene            19639..20502
                     /locus_tag="PC466_002576"
     CDS             19639..20502
                     /locus_tag="PC466_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 and DUF4163 domain-containing protein"
                     /protein_id="HDF2769943.1"
                     /translation="MKFFKVDTKAKVLRYVFVLTLTIMAVLAIKHDYKYNNLRKDASI
                     NLNSNKEAVTVMSNQSLPKGNTNSKQTLSVSTIGSKTIVKNDEYLESTINMPVITNSN
                     KIVERSTNDKIKNDIFEFYNKSYKEAKQYLKDNPDEKNKFVANVDFELKKNTDSALSI
                     KVRYYTYSGGAHGFYQDIAYNVDMRTGKFLELMDLFKDNTKYKEVIDEEIKRQIAELE
                     KKDEENIGIYNFKGIKENQNFYLQDENLVVYFDLYDITPYAAGIPEFSINKALISSML
                     KPEYVDLFDLK"
     gene            20569..21558
                     /locus_tag="PC466_002577"
     CDS             20569..21558
                     /locus_tag="PC466_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HDF2769944.1"
                     /translation="MLLLKKDDIKKVFTMRDAIEADKEAFRIYCEGKSVNPLRTNISV
                     PSQDASMLFMPGYVEELGCGGIKIVSVFPKNAQKGKPVIPATVLLLDGETGEVSAVLD
                     GTYVTQIRTGAASGAAIDVLAKKDSKIGALIGLGGQGEPQLEAMIEARNLDEVRVFSR
                     NRESREKFAEEMNLKLSKYNTKIVAVESSDEAIDNADVIVLATPSKQPVLNGNLVKKG
                     ALISAVGSYMPDMQELCPNCLTRASKIFFESTDAVLSESGDILIPLKEGKISKDDFSG
                     DLGNVINGTIPGREDDDEIIVFKTVGIGVQDVVTAKRIYDKAKENGIGIDWKW"
     gene            21650..22261
                     /locus_tag="PC466_002578"
     CDS             21650..22261
                     /locus_tag="PC466_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HDF2769945.1"
                     /translation="MKMVKKLILSTIMALVLVLTIGCSNAEEKVKSNFEANLAALEMY
                     KYDEKGISDALTEAEYKQIQTYNSKDKVSMIAQLTPLYGKENAEKIYETIVKLIQGVE
                     KTVTVESSSKDKITLKVVSKALDTSKVMSEANTLVKSYVTDEKNYDKKEKEVQDDMTK
                     MIIDLYNKKPTKEVTTMITYTKKDGKWQPPSNIQKLCEGIYTI"
BASE COUNT         8721 a         2628 c         3737 g         7300 t
ORIGIN      
        1 tataaaatac tagagcttgt tattaaaaat gctagaacaa attattataa aaatactaaa
       61 gcttgttatt aaaaatgcta gaacaaatta ttatataaaa tactagagct tgttattaaa
      121 aatactagaa caaattatta tgtaaaatac taaagcttgt tattaaaaat actagaacaa
      181 attattataa aaatactaga acttgttatt aaaaatgcta gaacaaatta ttatgaaaaa
      241 tattgaagct tattatgaaa aatgttagaa caaattacta tataaaatac caaagcttat
      301 tatgaaaaat gttaaaataa attattatat aagatactaa aacctatgta aaacaacttt
      361 aatatataac ttataaagtt gaagatacat aggtttttat ttttataatt taaagaggta
      421 tattatgata tttataattt aatcatatga taaactattt tggcagtatc atataattcg
      481 tctatattta catattcatt aactgtgtgt acatcataca tacctagact taatatagca
      541 caattatatc caagattagc taatatattt gcgtcacttc caccaccaat taccattgga
      601 tttggaacaa caccaacttg tcttattgct tcttcactta acttgaaaac gtgactatct
      661 ctactaagtt caaaactagg gtaagacata ctatgttcaa aggtataagt agtattaaat
      721 ttagatgcag catccttaca acatttttcc atatgattaa gctcatactc taaagtttca
      781 ggtatatgag acctaatttc agcagtcaat gtaaccttat cagttactat gtttgtagct
      841 ccaccacctt ctattttacc tatatttgaa gtagtcaatg gatctattct gcctatgtgc
      901 atattgctta ttgcatgaga ggctactaat atagcattta accctttttc aggttctata
      961 ccagcatgtg ctttctttcc atgaaaagag atttttatag attgttgagc aggagctttg
     1021 tatgctatcg aaccaatagc tccaccagaa tctaaaatca ccatatcttt acaaggcaag
     1081 ttgtcaggat taaagttttt gacaccatgc ataccagctt cctcacagat tgtaaaacaa
     1141 agataaatat ctctatgtgg tattttttct gtagtaacat gttctaaagc ttcaagtata
     1201 gcagctattc cagctttatc atctgcacca agtgtagtag ttccatcact tctaactaca
     1261 ttaccatcta gtattggttt tacacctaaa caaggttgaa cttggtccat gtgtgcacat
     1321 aaacaaagtg gtctacttcc ttcttcacct tttatatagg caatgacatt acctgtatta
     1381 ccaccatatt tttcacctgc atcatctata atggcatcta tatttctttc ttttaagtag
     1441 tttaccaacc acttagacat ttctaattct tgattagatg ggctatcaat tctaaccata
     1501 tccataaaat tatttataag tctattttta tctaacataa attatttctc cttttagaaa
     1561 gatttaaata aattacatgc tatatgaagg aagtattcca ggtcctagtg gaatattaaa
     1621 taccataaac aatattaata gtatagtcca cactattaag aatgatatag agtatggtat
     1681 catattagca attacagtac ccataccagc atctttatcg tattttcttg tgaatgctag
     1741 tataataggg aagtacggaa ataatgggct aagtggattt gttatacaat cacctatacg
     1801 ataagccatc tgagtaagtg ctggattgta tccaaccatc ataaacattg gtacaaatat
     1861 aggtgcaaga atagcccact ttgcagatgc actacctata aataaattta taaaacatga
     1921 taatataata aatcctatca acaataaagg tccatttatt cctgctgatt ttaaaaattc
     1981 tccgcccttt acagctagta tcagacctaa attactattt gtgaataatt gcaaaaattg
     2041 tgaagcagca aatgctagta ttatatatcc acccatatca ctcattgcac tagccattat
     2101 agagactaca tccttatcct tctttatttt acctatagtt tttccgtata caacaccagg
     2161 tatgaaaaat gctagtgcta ttataggtac catacctttc ataagaggag cattgtttga
     2221 tagtaaatct cctgtttctg ggtcagctaa gaatggtttt ttaccgatta cactaagagc
     2281 tactataata gctacatata ttaatatact tataccagct tttttaagcc ctttcttttc
     2341 tacatcacta agacttccat caacatctag ttctgcattt ccttcatatt taccaaatct
     2401 aggagctaca attttttctg ttacccatgt tgccaaaagt attagaacaa aagttgatgc
     2461 tatcataaaa aataagttca ttgttgcatt ggcttgaaat ccagaatcaa tcatttgagc
     2521 tgctggaact gtaaaacttg cagcaagtat atcattgaca cttatcataa tgtttgcggc
     2581 aaatcctaga cagactgctg catatccaga aaataaacct ataagtggat gtctaccaac
     2641 accaagatat acaagtgcag ctaatggtgg aaataatatt gtacctgcat ctgaagctat
     2701 attggcaagc atacctatag tcattacaac aagagttact cttgtttcag gaatcttgct
     2761 tactgatgct ttgattgttg ctgtcataag tcctgttttg tcacatacac cagcacctat
     2821 catagttact agaactagac ccaaaggagc aaacccttgg aaattgctaa ctatgtttcc
     2881 taaaagaatt tgaagctgtt ctacagtcaa taaatttact gcagttatag tttctccagt
     2941 accaggatga actactgata tccccataga accaactaga ctagatagta taagtaaaag
     3001 tacacataac cctaaaaata ttgtaactgg gtctggtagt ttattaccaa cagtttctat
     3061 tctgtttaat gtcctgtcaa aaaagttttt cttcttaact acgttatcat tcataatatc
     3121 ctccctaatg tttaaaaata taattaaaaa ataagtattg tggttgatct tacaatataa
     3181 attctgcttg tcgatttaag acgtgtccac aatatgtcct aaaaaaagta taaaataaac
     3241 tttttcctgt gtcaatgcag ttttctgaat tttctggttg agtggtgtta gttaaatatg
     3301 ctttaagtag attaatgacg aattatatct aatgtattta aatagcatat gcactttaaa
     3361 gttaatttta aaacaaaatt ttatgaaaag ctagtggaag attaagttat taaaataagt
     3421 agcgtagtaa agtgttagat tttttaatta atcaaagaaa tttactttgt attttctaca
     3481 aaaatctgtg aatatctttt gaattatgta gaggatataa atttatttta tttacataga
     3541 ttagattttg ttctaattta ctgtattcaa atggttttcc atgtccagga taaatcattt
     3601 taggttttgt attgatgatt gttttccaag attgaataaa ttctagtttg ctttctgcaa
     3661 atatggtaat tttgtgagta cttggaaatc cattcattgc agaatctcca caaaataaaa
     3721 caccatcatc aattagtagt gaaattgaat cagcagtatg tcctggtgta tctataattt
     3781 ttccatttag ttctttttca atttctttac gattcttgtc agacacaaga atacaccttt
     3841 tttcaaattc ttgtttaagt ggagaaaaac tatgctcacc ttttccaaat agtttcataa
     3901 tttggcaaaa gagaaaggca gtacggctgt tacaaccacc aataaaagag ttttgacctt
     3961 tatatagaat ttctaaagct ttatcatgca taacaatctt tgtattagga gattcgtcta
     4021 gaatctgatt tagaaaacca acatggtcat catgagcatg agttagaaat atgtatcgaa
     4081 tatctttgat ttttatgttg aatttagaaa ttcgtttttt gaaatgttta aaaccatttt
     4141 catatccagt atcaatcaag acaaagccat cttgaatagg gtacaaccat gtatttataa
     4201 ttcgatttcc tgcattaaac attttttcac caccttgaat tagaatataa atttatatta
     4261 attagaaaga atatagcata gttctactga tattttaacg tatctctaaa agttttaagg
     4321 aggataatat attttagttt aatctaaaag ctaaaagaaa agaagtatac tgttacaaaa
     4381 acaaagagtg gtataacttt tacagtagat accaccctat tataaaaata gacttataaa
     4441 gttttatcgt gtttttctag gaatgttaga tattcttctt tagtcataac tggagtaaag
     4501 gtatctaata tatctttagc atccttagca ttatcaaaaa gaaggtctac aactgtaagt
     4561 gccattgctt tagcaggaat tatgtaagct aaatcttcat caactatttc aaaatctctt
     4621 gtatgaagag ctccttttac accaccaatc atagggtgaa gagtaggcat tatatgagac
     4681 acatctccaa aatcaaaaga gcctgtaaaa tctccaccat caataacttt tccttttaga
     4741 cctaaatctt caagattgtt tttaaataaa ttatcaagac ttttgtatcg taatattgga
     4801 agatatccag gaatttcagt tatctcaaca tcagctccaa ctgccattcc accagccatc
     4861 aaagccttat ttattctttc attagcatca atcataccat ttatagttct agctctaaca
     4921 tatgattcca tatgaacatc agcaggaaca acatttacta tatctccacc ttttgtgatg
     4981 atagggtgga atctaactct ttcagactct ttaaaagttt ctctaagtgc attcacgttg
     5041 tttatagcaa gcattgctgc atttaaagca tttattccat catgtggagc agaaccagca
     5101 tgagattctt tacctataaa tttaaccttt tttccaacaa atccattact ctcaggacca
     5161 actagagcct tatcttctcc taaatcagaa gcatgaaaca tcatagatat gtctatatca
     5221 tcaaaataac ctctttttat taattcttgt tttccaccaa aataagttat ttttccttct
     5281 ttttttaatt gctctctgta ttccaactca ataaactctt cagcaggagt agccataaaa
     5341 gatactttac catctaaatg ttctaaaacg ccacttttta ctaaaccaac agcagcacct
     5401 aacattccag ctatttgaat attatgtcca caagtatgag aagcacctat ttcattagca
     5461 tctttatgtt ctttacatga tataccatcc aattctccaa gtatagatat atgaggacct
     5521 ttcttgctag aatttgcatc tgctttgcat cctgtaactg ctatattttt ttctacagat
     5581 aaatttaatt cttgctcaaa aaagtttgaa acagcttctg tagttttaaa ttctttatat
     5641 ccatattctg gatttttgta tattccttga cctattttta atattttttc tctattttca
     5701 tctatagttt ttattactag agattttaat tgttctttat tcataataaa ttcctcctat
     5761 attttacctt gaatacttaa aactatatga gctatactcg cacatgcaaa gaatatagtt
     5821 gtaaatacaa taagtgaaat tataactatt ttccatgaca tttcttttaa agcttctatt
     5881 ttgtttccaa cagaaattcc tgcaaaagct agtagtggag tagttatagc cataaagtta
     5941 atattattag tgttagttaa gaatacttca gatgttggac tatatggcat actaagtaaa
     6001 aggccgatta tagttgcaaa tccaaaagct ggaaagattg atttaggaaa taaatctttt
     6061 ataatcatag ctgccatagc agctaatatt agcatcacca taccaggaag agctgtaact
     6121 atagatgtac caacgctaat tctttgtcct ataagaatta taactccaat aacagacata
     6181 accaataatt gatatgaact tttctttaaa tttaaattag caaacattta ttagcactct
     6241 ccttctgtag atttaatttc tttagttttt ttatttctcg aaaatttagg ttctaaaatc
     6301 ttatacataa aattagtaaa tggtaaggat acaaaaacta agaatataat tcctgttata
     6361 ctagacatca tattgcttgt tgcagcatag gcaagtattg tatctgccat ttcaggtggt
     6421 accatggtag ataatgaacc agcagctgct gtcatcatac ttccactacc aacaccacag
     6481 gccattccca aagcatatgg gtgaagacca ctataaatag atattgaacc tagtacacta
     6541 aagtatatag taccaagaac tgttcccatt aaatatgtac caagtacacc actaccttct
     6601 ggtgagttta tcccatattt ttctgatata actcctaaag aaggttcacg acttatactt
     6661 gcagtagctc caacagcttc tcttttcatt ccaaacatta atgcaagagg taatgcaacg
     6721 attggtgcaa gtatatgacc aaattcttga gcgataaatg ctggtccagc ttgaattatt
     6781 ttgtcaatgt ttggtccaac tgtagtacca tattttatac caagcattac tagtgcaatt
     6841 ccaacaactt caccagcaat atttatttct ttttctccaa ccactttttt aagtgcttta
     6901 atttttttac ctaataaatc tggtgttatt ataagtccaa ttataactgc ataaagcata
     6961 gggaacagta ctatagaggc ttttccaata gctatagttc tttgccctat aaattcacat
     7021 attactacca agattaagca agttaaaaat acttgaataa aatgtttttt attaatttcc
     7081 atgatttcct ccccaaaaga ataaatattt tacttatctg aaatgagaaa atacgttttc
     7141 ttaagtataa tacgttttcc taaataaaat gaaaaaacta tttcaaataa gtttcagaaa
     7201 tgtcaataac atgtccttaa ttaaggataa aacaaaaatt taacattgtc aacgaaaaat
     7261 atctaaaata ttacatattt tgaatatatt gtaatatagc tttattatga aaaaattgtt
     7321 taaatattgt aggaataata gctaaaaagc tttaaaatta gtaatataaa attgaaaaat
     7381 aataatatag agttgagaaa tagtaaattg aaattttaaa ataaatgagt ggaagtagct
     7441 tagtaaagta tggaaatgaa tattacaata gaaaataaat aatatgtaaa gactttaaat
     7501 taattttaag tattaagtac aaatactaat ttttgatata gaaattgaat aaagtaaatg
     7561 ataataagca aatgaattaa gatgataata agtgaattga tatagaaata agtaaattaa
     7621 gtaagatgat aacaaatgaa atgataataa gtgaattgat atagcaataa gtaaattaag
     7681 taagacgata acaaatgaaa tgataataag tgaattgata tagcaataag taaattaagt
     7741 aagacgataa caaatgagat gataataagt gaattgatat agaaataagt aaattaagta
     7801 agatgataac aaatgagatg ataataagta aattgatata gtaataaata aattaagatg
     7861 ataatatcca aagtgagaaa gataatagaa agtaaataaa atcatgtaag aataatttag
     7921 ataagattct aagattttat ttatttaaaa attagtatga ttaatttaga ttaaataaat
     7981 ttaataattt tagtaggtgg taatgaatga aaataaatag attaacagaa ataatagtaa
     8041 ttctattaaa taaaaaatta gtaacagcta aagagttggc agataggttt gaagtttcta
     8101 caagaaccat atatagagat atagaaactc tgtctatgtc gggagtacca gtatatatga
     8161 cgaaaggcaa aggaggaggg atatctttaa tagaagaata ttctatagac aaggccatac
     8221 tgtcaaaaaa agataaagag agtttaatag ttgcactgaa aacattacag gcgactaagt
     8281 atccagaaat aaattcagta gtaaataaaa ttggctcaat atttggagag cagaattttt
     8341 caaactggat tgaaatagac tttactgaat ggggaagtaa ttttaatgaa gatgataaat
     8401 ttacaaaaat aaaagaagct attttaagac gtaatactat aaattttaat tatgtaaata
     8461 gtttgtcaag ccagacaaac agaactgtcg aaccactgaa gcttatgtat aagagtaaga
     8521 cttggtactt gtatggattt tgtaaactaa aagatgattt taggatattt agaattagta
     8581 ggataaggaa tttatctata aaggatgaag tattttcaag aaagataata gaagaagtat
     8641 gtttgaatga ttctaaagta attaaggaaa atactataac gttgaaattg aggtttaaag
     8701 aaaagatgct ttttagagta tttgatgatt ttaataagga tttaataact aaaaatgaag
     8761 atgatacata tgatgtaatt acagaatttc ctattggtga atggatttat ggatatattt
     8821 tatcgtttgg tgacaatgtt gaagtacttg aacctaaaga tgttagggat aatgtaataa
     8881 ctagactaag ggagttgtct aaaatttatt cattataata tgatgctaga ttaaagattt
     8941 tattaaatat ataatatctt gcatttagta tataatatct cactgagttt aattatatta
     9001 aaaatatgac ataaaggtgt cgtatattat aaattataat tgaattagtt caaaataaaa
     9061 tatattaata aaaacaaagt gaggtataaa gtatgaatta tgaaatagta gagataaatg
     9121 agaaaatagt tataggaata tcgaaggaga ctacaaataa agatggacaa gcggtaaatg
     9181 ctataggtga attgtggaaa aaatttatgg gcaaagggat atataatgct ataaagggta
     9241 aaaagaatga caagacaata ggtctatata cagattacca gggtgatttt acaagtccgt
     9301 atagctttgt tgcatgttgt gaagtaaata gtaattctga taaagagaag aatttagaag
     9361 aattaaacac taataatact gttggagaaa gtattattag taaagttata ctagcaggta
     9421 agtatgcaaa gtttgttata gtaggaggtc aaaaagaagt aggagatttt tggtttaagt
     9481 tttggcaaat ggattttgat aggacttata taagtgattt tgaagagtat caatgtaata
     9541 cttttgatac aaagaaacaa gaaattcata tttacatagg aataaagtag atttgttatt
     9601 actatattga atgaagtatt gagtatagta catttattat agatagtttt actatttata
     9661 actataagca gtaaatctgt aaaagattta ctgctttttt agtaattaat agtatcagta
     9721 tcactttgaa tcttcagaca tattcgtcat ttaatattgt ttattgataa atgatacttg
     9781 taaatataat gatttgttat ttaatttaaa atatgaaaaa aagtattata aacacattag
     9841 aatacttctg gatttatgag tatacaattt gaaaaatata aaaaataatg tataaagcta
     9901 aatctaattt aatcgataat acatatagag aaatataatt aagtaaataa acaactatct
     9961 attagatatt gagaaagtca aatcctatat gaatctacag aaatgatttt aatgaatctg
    10021 aaaaaatttt ttatacaaac ataaaaaagg tataaagttg ttttattata atttgattac
    10081 ttttgataac tttttatgtt ttatacaatt atatttttaa taactcgtca aaacgccaaa
    10141 catatattac aatagatata taagtttttt tgttgacaaa ttatgttaag agaattaagt
    10201 ataatatggc ataaataatt acttttattt atcaatgaaa tgtatttatt gtgtagcgaa
    10261 aaatagtcag atagtataga caataactga agataaaagc gtttattgtt gtacatatgg
    10321 aggagttagt tttatggaaa ataaaatttt gatagtagat gatgctattt ttatgagaat
    10381 gataattaaa gaagctctga gtaaaagtgg ctataataat ttaatagaag caaatgatgg
    10441 agaagaagcg tgtaatatat ttaaatatga aaagcctgat ttgatgttgc ttgatattac
    10501 aatgccaaaa aaagatggtt tagaggtgct aagagaaata aaaaagttgg attcaagtgc
    10561 taaggttgta atgtgctctg caataggaca agagaatatg attgtagaag ccataaaact
    10621 tggagcgtta gattttatag tgaagccctt caaaacagaa acattagtta aagttgtaaa
    10681 taatgtttta aaataaaagt gtaaatatac actgatacaa tgaaaagcaa ataaatgcaa
    10741 taataaaagg gaggggttta tattataaat tatttagaac ttgatgatgt tcatatagat
    10801 gctcttagag aaattggtaa tataggctct gggaatgcaa ttactgcact tgcatccatg
    10861 ataaatagca atgtagaagt attaatacct atggtcaaga tacttgaata taatgaagcg
    10921 acaaatttgc ttggtggtcc agaaaacaaa gtagtatgta ttttactcga tatgaaaggt
    10981 gatatcaatg gaatgtttat gtttttgttg gatgaatcaa taactcaact tatgctaagt
    11041 tctcttttta ataaagaaga agctttttta gatgagattg aggcaattga aatttcagca
    11101 attaaggaaa taggaaatat tatggcaagt tcatatgtaa atgctattgc atctatgtta
    11161 aacatgacta taagtgtttc aattccagat atatgtattg atatggttgg agctgttcta
    11221 aatgtgccta tgataagatt ttcagatgtt ggtgacaaag tcttatttat agaaaataaa
    11281 tttaaaatga gtgataatta ttttactagc cacattttga tgattccaga aatgagctca
    11341 cttagagaaa tactcgtgag gttgggatta gaagtatgaa tagagagata gtagtgaaca
    11401 ttgcagatat gaagatagcc tatagaccaa atgttttagt tacttatgca cttggctctt
    11461 gtgtaggagt atgtttgata gataaagtag ctggaattgg tggaatgtta cacgttatgt
    11521 tgccatatag taaagatgct attaacattg aaaataagtg taaatttgct gacacaggaa
    11581 taaatgagct cattaaatct atggagaata taggtgcaaa tagaatatat ataaaagcaa
    11641 aaattgctgg aggtgctcag atgtttttag gaagcagcaa ttcagtaatt gcaagtatag
    11701 gacataggaa tgttgaggca gtaaaaaaaa ctcttttagg attaaatatt ccaatattag
    11761 ctgaggacac aggtatgaat tatggtagaa caatacgttt ttacactgag acgggtgaat
    11821 tacttgtaga ttcaataaat aaaggtaaga agaaattata atatatattt catagaaagt
    11881 gtattttagg agggaggtat taaatgagat ttccagatga cccatattta gattatggac
    11941 taattgatga aggaattaag tatctaaagt ttaaagtaga tgagcaagat tttggggttg
    12001 aacttgaaaa ggtaatagaa attactggaa atcaagaaat tatatttatt ccagaactac
    12061 ctacatattc taaaggcata ataaatctaa gaggaaaaat cattccaata atagatatgc
    12121 gtttgagact taaaaaagat gaattaatga ctacaaattg catgtatata gtagtaactg
    12181 aaataaagga cttggtagtt ggatttgtgg ttgatagagt tgatgatata gtaagcttag
    12241 aaaaaagtaa aatatcacct ccaccaagag ttactataga atattcggat tattttgtaa
    12301 gtggcgttgg agaattagaa ggtaaaataa ttactttact agatttagag aaacttttga
    12361 cagataaaga tgaagtttta atagatgaat taatcaatgg gtttgattgc actatcatgt
    12421 aacataggga tgtagttgga gtgttattat aaaaagattg tgatgagaac atttaagaat
    12481 atagtggtat aattattaag tataaaaatt ttaaatcatt aaaatttgaa tatattatgt
    12541 ttaagagagg tttgtatatg aaaaataagc aacagggaac aattttagtc gttgatgata
    12601 gtgttctgat gtgtgactta atagataaaa cacttacaaa agataatttt aaggttaaaa
    12661 aagcatttaa tgcaatagag gcaaaagaat ttattgaaga atttatacca gacattattt
    12721 tgcttgatat aattttacca gataactctg gttttgagtt ttgtaaggaa gtaaaatcta
    12781 atactcgtac agcagatata cctataattt ttataacttc aaaaaataca gatacagaca
    12841 tagtaaaagg atttggtgta ggagcaattg actatatggt gaaacctttt agtatgacag
    12901 aattaaaagc tcgtgttata gctcatcttg aagtaaagaa atctcaagat aaattaaaaa
    12961 agataaataa tgaactggaa tcttctcttg aaaaattgaa tagactcgtt gtaagagatt
    13021 atcttacagg tctttacaat aggcgacata taattaatca gcttatggag caaagaagaa
    13081 ttaataaata tagtgaaaca tcaatatccc ttatccttgg tgatattgat gactttaagg
    13141 ttatcaatga tacttatggg catgaagcag gggatttcgt gttaacagta atatcaagta
    13201 taataaaaaa gaattgtaga caaattgata ctgtatcaag atggggtgga gaagagtttt
    13261 tgataatgct cacaaatact ccaatagaag gtgctaagat actttcagaa agaatccgta
    13321 aagagataaa ggagtttgat ttcaactata aagaacataa aataaagtgc actattacat
    13381 taggagtagt agaagtaaac tcaaatatat cattagaaga aaacatatcc ttagcagata
    13441 aagcaatgta tgagggtaaa aacttaggaa aagattgtag cgtagtgagt acaatgaaag
    13501 gattaaaaaa gatataaact tactttatga aggagtacag atatgaaaag agaagtaaag
    13561 ctttctaaat tagcaattgt attgctgatt attatagtat tggctgttct agcagggatt
    13621 ttttcttcta tttcatctta taaagcattt gaaaaagtag aaaaaagtat taatgatatg
    13681 aataatttga ggactcaaag tcagtatata aaagatacaa ctagagagat aagtgatgta
    13741 ttaagaagat atgtatttac aggagaaaaa aagaataaag atatttatga aaaagaatta
    13801 tacggaaaaa caagagaatc agctttaaac aaattagaaa aaattggtct tacaaagagc
    13861 gagtcaaata aaatcttaga agcaaaagaa atatcagatt ctttagtacc aacagaacaa
    13921 agtgcaataa aggcagtcga aagtaatgat aagagtaaag ctcaaagtat aatttttggt
    13981 agtgactata taaactccca agagaaaatg gattctttaa taaatgaatt tcaagaggat
    14041 atagttaccc gttcaaattc caaaattgta gaagtaaaaa aagaattaca aagtctaata
    14101 ttaagaacaa tatttatact ttccctttta ataatattga caataataga atatacagta
    14161 ataaaattaa agatagtgat tcctattaat agagtagaaa aacacttttc aagaattgca
    14221 tctggggact taagaacaag tatagacgtt gaagaaagta aatctgaaat aggactatta
    14281 gtgagttctg tcaaaaagat gcaaagtatg cttttaaatt acatagacct tatagacagt
    14341 acattaacta gtattgcaaa aggagattta agagtagaga tagaccaaga atttataggt
    14401 gattttaaat caattaaaat atctttagaa agtataataa actcttttaa tggtgatttt
    14461 tctgaaataa atttatcagc agaacaagtt gcaagtgctt cagaacaagt tgcagcaggt
    14521 gcacaagctc tttcacaggg tgctactgaa caagctagtt cagtagaaga attagcttcc
    14581 acgattaatg agatatcaga tggaattaag aagtgtgcag atagtgctag tcttgcatgt
    14641 gaggtatctg accaatctgc atcacaagtt ggttttggaa gtagatgtat ggatgatatg
    14701 atgacatcaa tgggtgaaat aagtgaaaaa tcgagtgaaa tatcaaaaat aatcaaaaca
    14761 atagatgaga tagcattcca aactaatatt ctcgcattaa atgcagctgt tgaagcagca
    14821 agagcaggtc aatatggtag aggatttgca gttgtagcag atgaagttag gtctttggct
    14881 ggtaaaagtg caaaagcagc tcaaaataca gctattctca tagaagaagc tattaaaaca
    14941 gtagaaaatg gtgtcagaat tgctaaagag actgcaaatg cattggactt ggtagtaaat
    15001 ggtgtagaaa aaactactaa ttatattaat ggtatttctt cggctgtaca tagtcaagaa
    15061 gtagcaatta cacagatttt atctggaata gagcaaattt ccatagtagt ccaaatgaac
    15121 tcagcaacag cagaggaaag tgcagcagcc tcagaagaga tgtctgctca agctcaaatt
    15181 ttaaaagaat tagtagaaaa atttcatcta aaggaaagtg aagtaagaga atcatcatgg
    15241 gtttaaatta tgaggtgaat attgaagtaa gagaattatc atgtatttaa attatgaggt
    15301 gaatattgaa gtaagagaat tatcatgtat ttaaattatg agatgtatat atattgaaat
    15361 aagagaatga ttgtgtattt aaattatgag gtacatatag tgagataaga gaatcatcaa
    15421 ggatttaaat tatgagatgc atatataata gaaaattatt tgtaggtcgt aggtgataaa
    15481 tgtgaattat attgaaccga gtatgagaca aatgttagat atgtttatat ttgagacaag
    15541 tttattactc gaacaattag atgaaattat gattcaaata gaaaaagaga aagtatttac
    15601 tcataacaac attaatgaaa cttttagaat aatgcatacg ataaaaggtt cagcatctat
    15661 gatggggtta gacaatatat ctgctttagc acatagtgta gaagacttgt tttatgctat
    15721 acgtgaaggt aaaatagaag ttttagacaa tgacctatta tttgatttag tctttcaatc
    15781 attagatttt ataagaagag atatagatga gctacaatca agaggttgta tatcttctga
    15841 ttactctaat tttattgaag gaattgaaga gtatgtgagt actttggaat tatcaagttc
    15901 tatgaaatca aaggataatg caaatttaga aagtacagac gaaaaagaag caatcgattc
    15961 aaattttgaa tacaaagaag actctgatgt agtaaaaata atctttgaac aaggttgcat
    16021 gatggaaaat gtgagagcgt tcatgcttgt atttgaactt agagattact gtgaatttat
    16081 agatttttat ccaaaagatg tagaaacaaa tgcagagtct acagaatata ttaaaagtta
    16141 tgggttttat atacaatttg tagctaaaga ggataaggca atagtttata aaactataga
    16201 agataatctc tatgtaaaag aatacataaa tattagtaaa aaagaaatag aaatgaaaaa
    16261 tacatcaaat aatgatgcag tagaaaataa attaaaagat aataataaag taagtaaaag
    16321 ttatcaaaat aactatacag aagatgagat acaagaagat gttttaaatg aaaaaactga
    16381 tatggaaaaa gatagtctaa gtgaagaaaa tgaacattta ccaataagta agcagagtat
    16441 tatgagtgta aatttagaaa aattggattt acttcaaaat atagttggag aaattgtaat
    16501 tatggaatca atggttgtaa atagcgtaaa ttctacaggt gttgatatag ataatttcaa
    16561 taaggcaaca agacaattac acaagcttac agatgaattg caagatatag taatgtctat
    16621 gcgtatgatt caaattgctg gtgtatttca aaaaatgcat agaattgtac gagatatgaa
    16681 taaaaaatta gataaaaatg tagagttaat aactatagga gcagagacag aggtagataa
    16741 gaatgtaatt gataatttag cagaaccttt tatgcacctt ataagaaatg ctatggacca
    16801 tgcaatagag cctattgagg agcgtatagc gaaaggtaaa gaagaagtgg gaaagatagt
    16861 tttatctgct gagaatctag gcggagaagc tgtgataagt atttcagatg atggtagagg
    16921 cattatgaga gataagattt tggcaaaagc taaggaacaa ggtcttctta aacatcaaat
    16981 taatgagtat actgatgacg aggtcaattc tttgattatg actccaggtt tttctacaaa
    17041 agaatctata actgaatttt ctggaagagg agtaggcatg gacattgttc gtaaaagtat
    17101 tgaaaaagtt ggaggttcaa ttgaagtaaa aagtaaacag gatgaaggga caacctttac
    17161 tataaaaata ccattaactc tttctatagt agagggtatg aagtttaaag ttggagattc
    17221 actatttact ttaccaatat catccataag aagaacattt aaacttacag acttaaatca
    17281 aataattaca gaaggaaata agacagagtt aattacaata tatggagcat gtattcccat
    17341 tataaggtta cataaaatat ataatattca aacaaaagta accaatctga tgcatggtaa
    17401 tatgataatt attgaaaatg agcataaagc agtatgcatt tttgttgatg aaataatagg
    17461 taatcagcaa gttgttgtga aaccatttcc agtttatttc aaccgattta atataaaaaa
    17521 taagggttta tcgggatgta caatacttgg ggatggaagt ataagtttaa ttatagatgc
    17581 agatagcatt atagaaatat attaggggat ttaaagtatg gctaaagatg aaattattaa
    17641 acaagtatta acattttatg taaatgatgt tatttatgga atagaattag aaaatgtgat
    17701 tgaaaccata agatttcaat caataacgta tgtaccatgt cttccaacat atataagtgg
    17761 agttattaat ttgagaggaa gaataatacc agttattaat atgcatataa agtacaatct
    17821 tcctaaagct gattataatg agagaacttg tataataatt acaaaggttg atgagtatca
    17881 agttggaatt attgtagata aagttgttga tgttattcat atagaaaatc taaatttact
    17941 agagacgact aattctaaca acactaatat taataaagat ataaaagaga ttgcgaaagt
    18001 tgaagataat tctatattaa ttttagatat tcgaaagttt ttgattaata gcatatagtt
    18061 agttctgata aattagcagg aggaagtttt tgcatgataa aactcacaga tgaagaattt
    18121 atagttcttg taaaccatgt aaaaaaagaa tatggtattg atttaagtaa aaaaagagcg
    18181 ttaattgaag gtcgcttata caatacaatg atagagaaaa aacttagttc ttttagtcaa
    18241 tatatgaatc tattatttaa agataagaca ggaaatgaag ctataaacct aataaataga
    18301 ttgagtacta accacacatt ttttatgaga gaacctcaac attttgagtt tatacagaat
    18361 agtatacttc ctttttggga agaaaataat aaaataagaa acataaatat atggagtgca
    18421 ggatgttcta gtggagaaga agcgtattca atagctatga ctttggatga ttattttgga
    18481 tataataaag agttgtggaa cattaaaatc atagccacag atatttcaac taactcactt
    18541 gaaaaagcta aaagaggtat atacatagaa tcaaatgtta acaatgttcc tgagttatgg
    18601 aagaagaagt attttataga caacaaggat ggtacattta aaatttgtga taagattaga
    18661 aaaagtgtaa tttttaagtc atttaattta atgaatgatt tctcatatca acattttgat
    18721 ttgatttttt gtagaaatgt tatgatttat tttgatttaa aaacaagaga agaacttata
    18781 aataaatttt ataatgctac caaaaaagat agttttttgt ttgtaggaca tgcagaagta
    18841 atcaacagaa gtagtactaa atacaaatat gtaaaacctg ctatatataa acgataaaaa
    18901 ggtatttttg atatatgatt ttttggaggc ggtaatgtgg aacgttttaa taatatggtt
    18961 attgctatag gcgcatctgt aggtggtaca gaagcaatac ttgaaattat aaaagaccta
    19021 ccaaaatcaa caccagggat tgttgtagtt caacatatgc cagctatatt tacttatatg
    19081 tatgcacaac ggcttgacaa gcagtgtatt atgaatgtaa gagaagctaa gaataatgat
    19141 agagtcgaac aaggaaatgt gttaattgca cctgggggtt accagatgaa attgtgtacg
    19201 gataaacaag gatattatgt aacttgtgaa aaaggagaaa gaataagtgg tcactgtcca
    19261 tcagtagacg ttttgtttga ttcagtagca gaagtagcag gtaaaaattc aataggaata
    19321 atacttacag gtatgggtta tgatggagca aatggacttt taaaaatgaa agaaaatggt
    19381 ttatttacaa ttggacagga tgaaaattct tgtatagtat atggaatgcc aatggtagct
    19441 tttgatagag gttctgttat gttacaatta cctcttggtg aaatttcaaa ctgtttgata
    19501 agacatatta atattttaaa acaaaaagat taatttttta taaataaaaa ttaatctttt
    19561 attaaattat atggataaaa aaccctagaa actccaaata taataagaga gatttatatt
    19621 taggaggaaa atgataatat gaaatttttt aaagtcgata caaaagctaa agttttaaga
    19681 tatgtatttg ttttaacatt gactataatg gctgttttgg caattaaaca tgactataaa
    19741 tataataatt taaggaaaga tgcttcaatt aatttaaata gtaataagga agcagtgact
    19801 gttatgagta accagtcatt accaaagggt aatacaaata gtaaacaaac tttatcagta
    19861 agtacaatag gaagtaaaac aatagtgaaa aatgatgagt atttagaaag tactataaac
    19921 atgcctgtaa taacaaattc aaataaaatt gttgaaaggt ctacaaatga taagataaaa
    19981 aatgacatat ttgaatttta taataaatca tataaagaag caaagcagta tcttaaggat
    20041 aatcctgacg agaaaaataa gtttgttgca aatgtagact ttgaacttaa aaagaatact
    20101 gattctgctc ttagtataaa agtgagatat tatacttata gtggtggagc acatggattt
    20161 tatcaagata tagcatataa tgtggatatg agaactggaa aatttttaga attaatggac
    20221 ttatttaagg ataatactaa atataaagaa gttatagatg aagaaattaa aagacaaata
    20281 gctgaacttg aaaaaaagga tgaagaaaat atcggaatat ataattttaa aggtataaaa
    20341 gagaatcaaa acttttactt gcaagatgag aatctagttg tatattttga tttatatgat
    20401 ataactccat atgcagcggg aataccagaa ttttcaataa ataaagcgtt gataagttct
    20461 atgctaaaac cagagtatgt agatttattt gatttgaaat agaagattaa attaaatgtt
    20521 atgctataat atttagcata gaaacttatt aaaattgggg gtataaaaat gctactttta
    20581 aaaaaagacg acataaaaaa agtatttaca atgagagatg caattgaagc tgataaggaa
    20641 gcttttagaa tttattgtga aggaaagagt gtaaatcctt tgagaaccaa tatatctgtt
    20701 ccaagtcaag atgctagtat gttatttatg ccaggatacg tagaagaatt aggctgtggg
    20761 ggaataaaaa ttgtatctgt atttcctaaa aatgctcaaa aaggcaaacc agtaattcca
    20821 gcaacagtac tattattaga tggagaaact ggagaagtta gtgcagtatt ggatggtact
    20881 tatgtaactc agattcgtac tggagcagcc tctggagcag ctatagatgt attggctaaa
    20941 aaagattcta agattggagc tttgataggt ctaggaggac aaggtgagcc acaacttgaa
    21001 gccatgatag aagctagaaa tttggatgag gtaagagttt ttagtagaaa cagggaaagt
    21061 agagaaaaat ttgcagaaga aatgaactta aaattaagta aatataatac taaaatagtt
    21121 gcagttgaat catctgatga agccatagat aacgcagatg tgatagtttt agctactcca
    21181 tcaaaacaac cagtacttaa tggaaactta gtgaaaaaag gagctttaat aagtgcagta
    21241 ggttcatata tgccagatat gcaagagttg tgcccaaact gtttaactag agcgtctaag
    21301 atattttttg aatcaacaga tgcagtttta tctgagtcag gagatatatt aattccatta
    21361 aaagaaggta agataagtaa agatgatttt agtggtgatt taggaaacgt tataaatgga
    21421 actattcctg gaagagaaga tgatgatgag ataattgtat ttaaaactgt tgggataggt
    21481 gtacaagatg tcgtaacagc aaaaagaata tacgataaag caaaagaaaa cggtattgga
    21541 atagactgga agtggtaaaa tattcaaaat aattctatag ttagacaaat ttatgttata
    21601 atgttgataa ataaattttt tattatttta attgagggag gatgtttgta tgaaaatggt
    21661 aaaaaagtta atattgtcta cgattatggc tctagtttta gttctaacta tagggtgttc
    21721 taatgcagaa gaaaaagtaa agtcgaattt tgaagctaat ttagctgcat tagaaatgta
    21781 taagtatgat gaaaaaggaa tttctgatgc attaacagaa gctgaatata aacagattca
    21841 aacttataac agcaaggaca aggtttcaat gattgctcaa ttgacacctc tttatggtaa
    21901 agaaaatgct gaaaagatat acgaaacaat tgttaaatta attcaaggtg ttgaaaagac
    21961 agtaacagtg gaatcttcta gtaaggataa gataactttg aaagttgtaa gtaaagcttt
    22021 agatactagt aaagtaatga gtgaagcgaa cactttagta aaatcttatg taactgatga
    22081 aaagaattac gataaaaaag aaaaagaagt tcaagatgat atgacaaaaa tgattataga
    22141 cctttacaat aagaaaccaa ctaaggaagt tacaactatg attacatata ctaaaaaaga
    22201 tggtaaatgg caaccaccta gtaatataca aaagttatgt gaaggaatat atacaattta
    22261 atttatttta aagacacaaa actatctttt aagcatataa taaaatgttt ggaagatagt
    22321 ttattttatt ttcaaagtat aaattatatt ttataaatga tttattttat aaataattta
    22381 tcttga
//
LOCUS       DAMJYN010000062        22236 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.063, whole genome shotgun sequence.
ACCESSION   DAMJYN010000062 DAMJYN010000000
VERSION     DAMJYN010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22236)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22236)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22236
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.063"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            145..1329
                     /locus_tag="PC466_002579"
     CDS             145..1329
                     /locus_tag="PC466_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769946.1"
                     /translation="MQKSVKKAKVTGSMLAIFGVASVLFSSHAGGGFATGNQETQYYV
                     QYGWTAPLMAILAMIILTATMREVIIMYNNNNCRNYKDLFCELWRPYPKLEIIWEIYY
                     YLMVLIAVSAVIAGAAAVFQSIGVNYFVAVFIIGVVLLVFTIFGAMLVSKAATAMTIA
                     ILVCTLTIFIVGIKAKVPEITEILSNRTSFTPGYIKPILNTFIYAGFQSVVIPTLAGC
                     SRPLLKNSKEATKAMIISFVMNAIALGLAVTMLMGWYREIIAAGQTTLPTLYVAGQSG
                     NHTIYIIYNVALFLCLMSTGVTTIFGLVNRFEDHKALSFLSSRMKRRVFTACAIMVVS
                     MLISLTGLSNIVKYGYGYCGYLGLFTIVIPFLTLGHYKNKKFAKENPEAKWPAELNEN
                     VN"
     gene            complement(1706..2815)
                     /locus_tag="PC466_002580"
     CDS             complement(1706..2815)
                     /locus_tag="PC466_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HDF2769947.1"
                     /translation="MDFKSLGISENTINILKKSGITTPTPIQKESIKLIKEGKDVIAE
                     AQTGTGKTLAFLLPIFENISLDINDIQVLILSPTRELAIQITEEAMKLKESKDVSILA
                     AYGGKDIGSQIKKLKGNIHMIIATPGRLLDHLNRKTIDLSKLKTFVLDEADQMLLMGF
                     KNEVEAILKETSNKKQTLCFSATINSQVKKLAYRYTKNPVVVSIQKEEITLNNIKQEV
                     VETTDRKKLDALCKVLDEDNPFMAIIFCRTKRRVDNLEEALAIRGYNCQKLHSDIAQS
                     KRERIMKSFRNLDIQYLIATDVASRGLDISGVSHIYNYDLPETPEDYIHRIGRTGRAG
                     EEGYTCAFIDPKNERMLSEIETAIESKISRRIIEL"
     gene            3278..4471
                     /gene="nifV"
                     /locus_tag="PC466_002581"
     CDS             3278..4471
                     /gene="nifV"
                     /locus_tag="PC466_002581"
                     /EC_number="2.3.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homocitrate synthase"
                     /protein_id="HDF2769948.1"
                     /translation="MCVISKDRAKEIKIVDTTLRDGEQTAGVVFANREKIMIAEMLSD
                     LGVDQIEVGIPTMGGDEKNVIKHICSRNLKSDIMAWNRAVIKDVEESISCGVDAVAIS
                     ISVSDIHIENKLRTSRGWVLENMAKTVEFAKKNGLYVSVNGEDASRADIDFLTEFINV
                     GKQAGADRFRYCDTVGVMNPFSIKNAIETLYERTNFDIEMHTHNDFGMATANALAGIA
                     AGANYVGVTVNGLGERAGNAALEEVLMALKCVYKCDLNNIDTRKFRGICEYVAQASGR
                     ILPTWKPVVGDNMFIHESGIHADGALKDPHNYEPFDPSEVNLERKIVIGKHSGRAAVI
                     NKLSEYEMYISPENATKLLNAIRATSIRLKRSLMDKEILQLYCDILAHEKGTTEEEAV
                     RGSYI"
     gene            4496..6421
                     /locus_tag="PC466_002582"
     CDS             4496..6421
                     /locus_tag="PC466_002582"
                     /EC_number="4.2.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aconitate hydratase"
                     /protein_id="HDF2769949.1"
                     /translation="MGDNIVYKIIKKHIVDGEAVAGSSIGIKIDQTLTQDSTGTMTYL
                     QLEAMGIDKVKTKRSVAFVDHNMLQQGFENADDHKYIQTVADKYGVYFSKPGNGICHQ
                     VFLERFSTPGDTLLGSDSHTPTAGGVGMMAIGAGGLDVALAMAGGAYYIKAPKVCKVN
                     LVGKLNNMVSSKDIILEVLRKQTVKGGVGKVYEYGGEGVKSLSVPQRATITNMGAELG
                     ATTSIFPSDEKTLEFFKSQGREDAWIELKPDADAVYDEEITINLDELKPLAAKPHSPD
                     NVDEVENIGKIKIDQVAIGSCTNSSYEDLMKVAQILKGNKVHKDVSLVIAPGSRQVME
                     MIARNGALADIISAGARILENSCGPCIGMGQSPGTDSVSLRTFNRNFYGRSGTLSAQV
                     YLVSPEVAAVSAIKGVLTDPREFDIKFTNLDVNEFLIDDSMIIKPADVGSNVEVVRGP
                     NIKPFPLNTELSQSIGGKVILKTEDNITTDHIMPSNAKLLPFRSNIPYLANYCFNTVD
                     TEFPQRAKDNNGGFIVGGDNYGQGSSREHAALAPLYLGVKGVIVKSFARIHKANLINS
                     GIIPMEFCDEKDYENISLLDNLEIPNILDNLGSGILEVKNTTKGTSFKVKVELSAKEV
                     DVLKAGGKLNYTKNQAN"
     gene            6443..7438
                     /locus_tag="PC466_002583"
     CDS             6443..7438
                     /locus_tag="PC466_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isocitrate/isopropylmalate dehydrogenase family
                     protein"
                     /protein_id="HDF2769950.1"
                     /translation="MYKVTLIPGDGIGPEVAKAMKKVVEATGAEIEWEEVNAGEAVIE
                     EYGTPLPEYIIDSIKKNKIAIKGPITTPVGKGFRSVNVTLRQALDLYVNLRPIKSFKG
                     IKSRYEDVDLVVVRENTEDLYAGIEHKIGDYAAESIKIITRSASERIVDFACNYVKDN
                     KRKKVTAIHKANIMKMSDGLFLDVFREVASKHGVEYDDLIVDAAAMNLVLNPENYDVM
                     VMPNLYGDILSDLGAGLVGGLGIIPSANIGKDCAIFEAVHGSAPQIAGQNKANPTALI
                     QSSVMMLRYLGEYENAQKIETALEKVFLEGSKLTVDLGGSASTTEFADEVCKYIV"
     gene            7765..8238
                     /locus_tag="PC466_002584"
     CDS             7765..8238
                     /locus_tag="PC466_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF2769951.1"
                     /translation="MVGSVEVCLIKTLDSNILREVGTLSRAVNSINDIKYKELKLQKG
                     QFTFLTRICENPGINLVELSNMLKVDKATTTKAIQKLIKAGYVDKKQDEFDKRGYNLT
                     PTDKSLEVYELIIEEENRSIEICFDNFTDEEKQVVTKLLEKMSKNVENEWFKVKR"
     gene            8272..8766
                     /locus_tag="PC466_002585"
     CDS             8272..8766
                     /locus_tag="PC466_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2769952.1"
                     /translation="MIRKANMNDLESIMKIIKSTVEEMKTYNNTQWDENYPLEKDFVS
                     DIKKQDLYIYEVDGEVAGFICLNYEEPEEYLGLNWSSNKKAMVIHRMAVNPNFRKTGI
                     ASKLVDFAEKLAVENNVSYLKSDTYSINSKMNLLLTKCGFIKIGEMSFLGKEKSFYCY
                     DKIL"
     gene            8863..9384
                     /locus_tag="PC466_002586"
     CDS             8863..9384
                     /locus_tag="PC466_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDF2769953.1"
                     /translation="MIGFLKKRRSIRKYKDVEVEKEKLDKILKAALLAPSSKGLRTWE
                     FIVVDDKEKLINLSQCRTKGGGFFLKNAPLAIVIIADKEKNDVWIEDASIAASYIQLQ
                     AHELGLGSCWIQVRNRMYDDNIEADKYIREELKVPSKYSVECIISIGYSDEEKKAYND
                     SDLDYKKVHFNNF"
     gene            9573..9884
                     /locus_tag="PC466_002587"
     CDS             9573..9884
                     /locus_tag="PC466_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HDF2769954.1"
                     /translation="MGIFKTKMDEDWKVNYIKEFNEMRDSYESKLQKKQFEVDSLKSE
                     LDRLRSYKNSLKPKEKQITDDDINNIKSLRRDGLSYKEISNQTSWSKATVSRVLNGLY
                     D"
     gene            9912..10598
                     /locus_tag="PC466_002588"
     CDS             9912..10598
                     /locus_tag="PC466_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDF2769955.1"
                     /translation="MKYSYKKCIIDSILLMFIIQILRMILNYVLLSQFEFTLENFNII
                     NLISFTLVGLSLILFLKDNSLYNKVRNRKITEAFEENKNNILIEKCKLILFVVVLSLA
                     IIVTYCTKGYVLFNVTMMTLSVLIVPIFEELFFREYIWNYLSNFIKSKSKIICITSIL
                     SGIYNIGYIDVIRNYVILYNNSSYTFEVIISKIMIGTVFGIVLGLVKYRFRDVGFCIL
                     LRSLFAIFIR"
     gene            10830..11714
                     /locus_tag="PC466_002589"
     CDS             10830..11714
                     /locus_tag="PC466_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="HDF2769956.1"
                     /translation="MKFVTFCSSNEEKIGVFNSETNSIYEINSLGLSKLYTDMNDFIE
                     NVSTGDLEKIKNNSFENAKCYKLEEVKLCSPIVRPKKDIICLGLNYKDHVNEIPDGVI
                     KNVVMPDYPIYFSKRADKIIGVDDKISLHGDLVEKLDYESELAVIIGKEGINISKEDA
                     YEYIFGYTIVNDISERALQDKHVQWFRGKSLDTHTSMGPCIVHKEEFEHPLKLDISSV
                     VNGEVRQNSNTEYFIFDIPTIINDLSRGMTLKPGDIISTGTPAGVAMGMNPQVYLKHG
                     DIVECKVEGIGVLKNIVD"
     gene            11813..12988
                     /locus_tag="PC466_002590"
     CDS             11813..12988
                     /locus_tag="PC466_002590"
                     /EC_number="2.1.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolecarboxamide
                     formyltransferase"
                     /protein_id="HDF2769957.1"
                     /translation="MARELELKYGCNPNQKPSKIYMKNGELPIEVLNGKPGYINFLDA
                     FNSWQLVKELKEATGLPAATSFKHVSPAGAAVGVPLSDTLKQIYFVDDLELSPLACAY
                     AMARGADRMSSYGDFIALSDVCDKETATIIAREVSDGIIAPGYTDEALEILKGKRKGN
                     YNIVKIDENYTPEPIETKDVYGITFEQGRNEILINEELLKDIPTANKIFTDSAKRDLI
                     IALITLKYTQSNSVCYAKDGQVIGVGAGQQSRIHCTRLAGNKADTWYLRQHPKVLNLK
                     FKKDIGRPDRDNTIDVYLSDDYMDVLADGIWQNFFEEKPEPLTGEGKRAWLKTLTGVA
                     LGSDAFFPFGDNIERAKRSGVSFIAQPGGSIRDDNVILTCNKYNIVMAFTKNRLFHH"
     gene            13116..13970
                     /locus_tag="PC466_002591"
     CDS             13116..13970
                     /locus_tag="PC466_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769958.1"
                     /translation="MALNIRNYSLLCNQGTAKFNEDVVGINPFGAWVLDGATGLNGKN
                     LVSNESDARWYVQWWNRYLYKNINKEESLKSIINTGIIEVKKEYELRLNGFKVEKLDL
                     PSSSIVVVKFHENKVEYFLLGDCALFIKNGDSKVIKDRSICKFDNTVFDEMSKLSNLE
                     EMAFDEIRTSVMDTIVSNRLKKNTKEGYWILDFDEEAVENSIYGYIEIKKDFQLMLTS
                     DGFTSACDRYNLIKEEELIRIAEKFGIGYIHNKVRDFEDNDYKAVKVPRFKIKDDSSC
                     LYLDIYND"
     gene            14014..15249
                     /locus_tag="PC466_002592"
     CDS             14014..15249
                     /locus_tag="PC466_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HDF2769959.1"
                     /translation="MKILHIITQKPNSTGSGIYLSGMIKGFEKIGHKQAVIAGIDVND
                     DVNCFPSEVSFYPVKYNCGELNFPVVGMSDSMPYESTRYKDLNIDMINRLKYQFKVNI
                     DKAMNDFKPELIICHHLYLLTAFVREIVKDIKVMSICHGTCLRQLNTIDLEKEYIIAN
                     IRKLDLIFALHENQKYDIIKTFGVSESKVVVIGSGYNDDIFYNKNYKIKDDKIKIVFA
                     GKICKSKGLIPFIKSISKLKYSKDLIEVNFAGTGSDIESYNEIVKLASKSPFKMNFLG
                     KLEQRDLAELFNRSQIFVLPSFYEGLPVVVLEALSCGTDVITTDILGVKEWIGSEINN
                     SGKIEYISLPFMEKEGIPKDEELYDFENNLYNAIDSKIQSLLNNSNEKTSVDMSKKTW
                     DGLAYRINEVILMDELCLV"
     gene            15350..16291
                     /locus_tag="PC466_002593"
     CDS             15350..16291
                     /locus_tag="PC466_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp25"
                     /protein_id="HDF2769960.1"
                     /translation="MRISKKVLALGISALLLSVSFPTSINALDKIENIQGVDKYETAG
                     LISDKQDFTTAVLINADSTMVDGIAASGLAGVNNAAILLTNKDDIPEATLQRLNRVTK
                     IYVIGGENSISKDVEKMLLMRRMQVIRIDGVDRVDTSYKIAGEIEKIKNSDKMFLVNG
                     FKDEADAVSVASVAYRDGAPIILTKDIPSAEEDTDLDPWFGVSPVPVYAIGGESTLSD
                     YIVSRYRATRIGGVDRYQTNKNVIEKFYNGAKEFYITSGDDLVYALVASPLAKNAPVV
                     LVSNKSDKSILSGASKVTAIGISDKSIIEQCLDAVKK"
     gene            complement(16520..16873)
                     /locus_tag="PC466_002594"
     CDS             complement(16520..16873)
                     /locus_tag="PC466_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HDF2769961.1"
                     /translation="MDRKRELKQLYKEMKFDTGVFIIKNDITKKIYLGKSNDIKSKFN
                     SLKFQLGAGSCMIKELNNEWKKYGEKAFTFEVLELIKHDDNKTEKDYLEELDILEMIW
                     LEKLKEDNTYEIYSI"
     gene            17169..18080
                     /locus_tag="PC466_002595"
     CDS             17169..18080
                     /locus_tag="PC466_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CGNR zinc finger domain-containing protein"
                     /protein_id="HDF2769962.1"
                     /translation="MNKKIELIGNFASDWIRYSDYEYKITEEDELYIVPTEDAVFTMY
                     NPFDVADDIIVDIIRIGQEALQDISKETKEMKLKKEVLEFVKKYGLLGLIYSSVYNRD
                     IVGEERVLMIEKNYITKENILSTDEYVNMFIPFASDEDVYFKKYRRGIDVSKREESPK
                     FFGKRPLILDLVFSKFYTEQLDWIVSFAKDMCKHFNQICVYKNTSNLLTESVTIMSGG
                     FNPQKIGFSISQLDKPIIAWEFDSLKTAIETIYAFAITSEPSSLNKCKYCGKIYIPTN
                     SKSQYCSPSCRNCSNVKKSRSRAKKDK"
     gene            18340..18774
                     /locus_tag="PC466_002596"
     CDS             18340..18774
                     /locus_tag="PC466_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769963.1"
                     /translation="MISPIILSSINQNLKEIERNELLETNIESGDYGLALSESDVKDI
                     INSRDNTLKGYGRIELDIKVTKQLIENIYTSQYTNVDNYLEAINDMQEIFYYLKNETD
                     DKICDDEIIEILGEFYEKFSGNMDNVRGEADEFAKKFKFGEV"
     gene            18797..20332
                     /locus_tag="PC466_002597"
     CDS             18797..20332
                     /locus_tag="PC466_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769964.1"
                     /translation="MLNNLSNININENNLIKNQYSISLLKECLNCKVIDEREVYNIQQ
                     EISLILMDLIKKYTNGQSTSVKTEVAEKLLISIWYAIDAYINKLGDIEKRVVELTAKN
                     VKKVYLGGIEILEEELVRLKDFYKLMMSRKLDTNSIAYNDTLMELSSFFKSYIVKFEA
                     QDVPVSIDYPLALDDMDVKGIYYVKNYIESIDIENRFCNLFKKKDREKLFYDYGVIYK
                     IDCDVILVNLFELIINNCIFSTILGNEVINLEISKYEYEFLEKQFKNMYNNITEDKVI
                     GSEESNIIELIEVDDSFNTEVDSNLDYNDFEEINREIRINKKITLLLMEAIEVLIKRL
                     SIEDEDVIRYIKKYEKIFIESVLSSIKSNTFKSMVTVSKNKNEHLEDYIVDDESKLDD
                     ESFREIFNEILDSTSIIEKIRIIKENINAKKDFIDILESECLFGEEYLMLFASLSELE
                     LAILGSVVFYEDIRMREINILEFMLNEKTETTLWKTEYIKFMKRQSEDKIYSIEEHMN
                     KIN"
     gene            20416..21783
                     /locus_tag="PC466_002598"
     CDS             20416..21783
                     /locus_tag="PC466_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2769965.1"
                     /translation="MKEYIINNVEEIREELIDLSKKIWENPELAFEEKYASSIQKEYL
                     KSKGFKIEEVENLPTGFIASFGEGKPVIGILGEYDALPELSQCVSAERKPLVEGKAGH
                     GCGHNLLGVAGVGAVVSIKKLIEENKFNGTIKYFGCPAEEEGGGKTVMCINGCFDDVD
                     CAFTWHPFDINAPWRGGSLANLSVKFKFKGITAHAAQAPHNGRSALDAVEIMNVGANY
                     LREHVIDSIRMHYVITNGGGRPNVVPGFAESWYFIRGKKARDAEHVLDRLIKVAQGAA
                     MMTETEMEYKVTDGIYDYIPNQCLTDLVYDNMVFVGCPKNTPEEEEFAKKLCDTLTRE
                     ERLGVATSLQNDKSIVESYIHKEIVDGDKDKGLAGSTDVGDVSYVIPVAQFAMAAWPV
                     GIASHTWQSCSSAGSNIGFSAMINSAKVLACSAYDVFMNTKIIDEAKIEFDKSLDGQK
                     FKPLV"
     gene            21818..22042
                     /locus_tag="PC466_002599"
     CDS             21818..22042
                     /locus_tag="PC466_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NifU family protein"
                     /protein_id="HDF2769966.1"
                     /translation="MREKVEKVLEEKIKPVLQRDGGDVELIDVNENGVVLVRLQGACS
                     GCPGATMTIKAIIENVLVSEVPGVTQVLGV"
BASE COUNT         8689 a         2225 c         4060 g         7262 t
ORIGIN      
        1 atatttaata caaaggtaga aataagttga aaatgtaaag tcattggaaa aatatagttg
       61 aatttaatga acaaaaatgt tattgtttta tcaatgaagt gttaaaataa aaactttcaa
      121 tatcatttta gggaggatga tttcatgcaa aaaagtgtaa agaaagcaaa agtaacggga
      181 tctatgttag ccatttttgg tgttgcaagc gttcttttta gttcacatgc aggaggagga
      241 tttgctacag ggaatcaaga aactcagtac tatgtgcagt atggatggac agcaccactt
      301 atggcaattt tagcaatgat tatacttact gctaccatga gagaagttat cataatgtat
      361 aataataaca attgtaggaa ttataaggat ttattttgtg agctttggag accatatcca
      421 aaacttgaaa taatatggga gatatattac tatctaatgg ttttaatagc tgtaagtgct
      481 gttatagcag gtgcagcagc agtatttcaa agtataggag taaattattt tgtagctgta
      541 tttattattg gagttgtact tcttgtcttt actatatttg gtgctatgct tgtatctaaa
      601 gcagctacag caatgacaat agctattcta gtatgtactc ttactatttt tattgttggt
      661 ataaaagcta aagtaccaga aataactgaa atattatcaa atagaacgag tttcacacct
      721 ggctatatca agccaatact taatactttt atttatgcag gttttcaatc ggttgttata
      781 cctacacttg caggatgttc aagaccactt cttaagaact caaaagaagc tactaaggca
      841 atgataattt catttgttat gaatgcaatt gcattaggac ttgctgtaac tatgctaatg
      901 ggatggtata gagaaattat tgctgctggg caaacaacac tccctactct ttatgttgca
      961 ggtcaatctg gaaatcatac tatatacata atttataatg ttgcattatt cctttgttta
     1021 atgtctacag gagtaactac tatatttggt cttgtaaata gatttgaaga ccataaagca
     1081 ctttctttcc tttcttcaag aatgaaaaga agggtattta cagcttgtgc aataatggta
     1141 gtgtcaatgc ttatatcact tacaggatta agtaatattg ttaaatatgg atatggatat
     1201 tgtggttatc ttggtctatt cactatagta attccattcc ttacactagg acattataag
     1261 aataagaagt ttgcaaagga aaatccagaa gctaaatggc cagcggaatt aaatgaaaat
     1321 gtaaattaga tgtagtagca aaaaatattg ctaaagagaa tactataaat aagaatacta
     1381 tagataatat atctgcatgt ttattaagat tatttgcaaa atctaatatt gaacaactat
     1441 aaacaagcaa tataaaacta agaataaaag ataaaaagag ggtgtctcaa aatggacttt
     1501 tagtttataa ggcactcttt tttatatgaa gtcaaatata ttttcattat tttgacaata
     1561 aaagagacta atcctacttt ggatagcctc ttttttcttt aatataaaat agtataacag
     1621 caaagtatag attgatacat gttttctgta gctttctata tattacagtg tttgtgtggc
     1681 attggtattt taagcaatct ataaattata attctataat tcttctacta attttagatt
     1741 ctatagccgt ctctatttca cttaacattc gttcattttt agggtcaata aaagcacatg
     1801 tatagccttc ttcaccagct ctaccagttc taccaatacg gtggatgtag tcttctggtg
     1861 tttctggtaa atcgtaatta tatatatgac ttactccaga tatatcaagg ccacgagaag
     1921 ctacatctgt agctattaag tattgtatat ctaaatttct aaatgatttc attattcttt
     1981 ctcgttttga ttgagcaata tcactatgaa gtttttgaca attatatcct cttatagcaa
     2041 gagcttcttc aagattgtca acccttctct tagtcctaca aaatattatt gccataaaag
     2101 gattatcttc atctagtacc ttacataagg catctaattt ttttctatct gtagtttcta
     2161 ctacttcttg ttttatatta ttaagagtga tttcttcttt ttgaatagaa actacaacag
     2221 gattttttgt gtatctataa gctaattttt ttacttgaga atttatagtt gcagaaaagc
     2281 atagtgtttg ctttttgttt gaagtctctt ttaaaatagc ttccacttcg tttttaaatc
     2341 ccataagcaa catttggtct gcttcatcta aaacaaaagt ctttaactta ctaaggtcta
     2401 ttgtttttct atttagatgg tctaaaagcc tacctggtgt agctataatc atatgaatat
     2461 ttccttttag tttctttatt tgagaaccaa tatcttttcc tccatatgct gcaagaatac
     2521 ttacatcttt agattcttta agtttcatag cttcttctgt tatttgaata gctagttctc
     2581 ttgtaggaga aagtataagt acttgtatat catttatatc taatgatata ttttcaaata
     2641 tcggaagtaa aaaagctagt gtttttcctg ttccagtttg agcttctgct attacatctt
     2701 ttccttcttt tattagttta atactttctt tttgtatagg tgtaggtgtt gttattcctg
     2761 atttttttag aatatttatt gtattttcac taatccctaa gcttttgaaa tccattgtta
     2821 tcttaccttt catgaaaaat tttctttttt attaaccaat taataatatc atatttgtaa
     2881 gtatttttag taaatttttt aattattatt tatatagctt aaaaatatat taagatactt
     2941 taaaatggaa tgtaacttaa cttaaatttt agtaggaatt ttataggttt atttttaaag
     3001 gttttttgaa aataaatcta tttaaaaatt aaattaaaat gcaagaaaaa cataataact
     3061 ttcattttta agaagttttc acaaaaaaga aaaaatatag tgcaataaat gatacaaagt
     3121 aatataatag attacaagat atgaaaagct aaaaaaataa attgcaaatg aaattaaaat
     3181 gaataaaaaa taaaaaaata atcataagtt agaggtatca atgaaaaata agacttaatg
     3241 tttttaaaat taaaagtata ctaagggggg cattaatatg tgcgttatat caaaagatag
     3301 agcaaaggaa ataaaaatag tagatactac tttaagagat ggagagcaaa cagctggggt
     3361 tgtatttgca aatagagaaa aaataatgat tgctgaaatg ttaagtgacc taggtgttga
     3421 ccaaattgaa gttggtatac ctactatggg tggagatgaa aaaaatgtaa taaagcacat
     3481 atgtagtaga aatttaaaat cagatataat ggcttggaat agagcagtaa taaaagatgt
     3541 tgaagaatct atttcttgtg gtgttgatgc agtagctata tcaatatcag tatctgacat
     3601 tcatatagaa aataaattga gaacttctag aggctgggtt ttagaaaata tggctaaaac
     3661 agttgaattt gcaaagaaaa atggattata tgtttcagta aatggagaag atgcttcaag
     3721 agcagatata gacttcttaa ctgaatttat aaatgttgga aaacaagcag gggcagatag
     3781 atttagatac tgtgatacag taggagttat gaatcctttt tctataaaga atgcaataga
     3841 aactctttat gaaagaacta attttgatat agaaatgcat acacataatg actttgggat
     3901 ggcaactgca aatgcacttg caggaatagc agcaggagca aattatgttg gtgttacagt
     3961 aaatggatta ggtgaaagag caggaaatgc agcattagaa gaagttttaa tggcacttaa
     4021 gtgtgtttat aaatgtgatt taaataatat agatactaga aaatttagag gaatatgtga
     4081 gtatgtagca caggcatcag gaagaatact tcctacatgg aaaccagtag ttggggataa
     4141 tatgtttata catgaatctg gtatacatgc agatggagct ttaaaagacc cgcataacta
     4201 tgaaccattt gacccaagtg aagtaaatct tgaaagaaaa atagtaatag gtaaacattc
     4261 aggaagagct gcagttataa ataagttgag tgaatatgaa atgtatattt ctccagaaaa
     4321 cgctaccaag ctattaaatg ctataagagc tacatctata agattaaaaa gaagtttaat
     4381 ggataaagaa attcttcaat tatattgtga tatactagca catgagaaag gcacaacaga
     4441 agaagaagca gttagaggtt catatattta agatataatt gtttaggagg aaaatatggg
     4501 agataatata gtttataaaa taattaaaaa acatatagta gatggagaag ctgttgctgg
     4561 aagttcaatt ggtataaaaa tagaccaaac tttaacacaa gattctactg gaacaatgac
     4621 atatcttcaa ctagaagcta tgggaataga taaagtaaag actaaaagaa gtgtggcatt
     4681 tgtagaccat aatatgttac aacaaggatt tgaaaatgca gacgaccata agtatataca
     4741 aacagtggca gataaatatg gagtttattt ctctaagcca ggaaatggta tttgtcatca
     4801 agtattttta gaaagatttt caacaccagg agatacactt ttaggttctg atagccacac
     4861 acctactgct ggaggtgtgg gcatgatggc tattggagct ggtggattag atgttgcttt
     4921 agccatggca ggaggagcat actatataaa agcaccaaaa gtctgtaagg tgaatctagt
     4981 tggaaaatta aataatatgg tatcatcaaa agatataata ttagaagtgt taagaaaaca
     5041 aactgtaaaa ggtggagtag gtaaagttta tgaatatggt ggagaaggtg tcaaaagcct
     5101 atctgttcca caaagagcta caataacaaa tatgggggct gaacttggag caactacttc
     5161 aatcttccca agtgatgaaa aaacactaga attttttaag agtcaaggaa gagaagacgc
     5221 atggatagag ttaaaaccag atgcagatgc agtttatgat gaagagatta ctataaactt
     5281 ggatgaatta aaaccattag ctgcaaaacc tcatagccca gacaatgtag atgaagttga
     5341 aaatataggc aagattaaaa tagaccaagt ggcaatagga agttgtacaa attcttctta
     5401 tgaagactta atgaaagtag cacaaatcct gaaaggaaat aaagtacata aggatgtgag
     5461 tttggtaata gcaccaggtt caagacaagt tatggagatg attgctagaa atggggcttt
     5521 ggcagatata ataagtgctg gagctagaat actagaaaat tcttgtggtc catgtattgg
     5581 tatgggtcaa tctccaggta ctgactctgt gtctttaaga actttcaata gaaatttcta
     5641 tggtagaagt gggactttgt cagcacaagt atatttagta agtccagaag tggcagcagt
     5701 aagtgcaatc aagggagtgc ttacagaccc aagagaattt gatattaaat ttacaaattt
     5761 agatgtaaat gaatttttga tagatgatag catgataatt aaacctgctg atgtaggaag
     5821 taatgtagaa gtagttagag gacctaatat aaaacctttc cctcttaata cagagctaag
     5881 tcagtctata ggtggaaaag ttatattaaa gacagaagat aatataacta ctgaccatat
     5941 aatgccatca aatgctaagt tacttccttt tagaagtaat ataccgtatc ttgcaaacta
     6001 ttgtttcaat actgtagata cagaatttcc tcagagagca aaagacaata atggtggatt
     6061 tatagttggt ggagataatt atggtcaagg ttcaagtaga gaacatgcag ctttagcacc
     6121 attatatcta ggtgttaaag gggtaatagt taagagcttt gcaagaatcc acaaggctaa
     6181 cttgataaat agtggtataa ttccaatgga gttttgtgat gagaaagatt atgaaaatat
     6241 atctctttta gataatctgg agataccaaa tattttagac aatctaggta gtggaatttt
     6301 agaagttaag aatacaacta aaggaacttc ttttaaggtc aaagtagaat tgtcagcaaa
     6361 agaagttgac gtattaaaag ctggtggaaa attaaactac actaaaaatc aagctaatta
     6421 atatgaaaag agggaatatt gaatgtataa agtgacactt ataccaggag atggaatagg
     6481 accagaagtt gcgaaagcta tgaaaaaggt agtagaagct actggagcag aaatagaatg
     6541 ggaagaagtt aatgcaggag aggcagttat tgaagagtat ggtactccac ttcctgaata
     6601 tattatagat agtataaaaa agaacaaaat agctataaaa ggcccaatta ctactcctgt
     6661 aggtaaagga tttaggagtg taaatgtaac tttaagacag gcattagatt tgtatgtcaa
     6721 tttaagacct attaaaagtt ttaaggggat aaaatcaaga tatgaagatg ttgatttagt
     6781 ggttgtaaga gaaaatacag aagatttata tgctggaata gaacataaaa taggtgatta
     6841 tgcagctgaa agtataaaga taataacaag aagtgcaagt gaaagaatcg ttgattttgc
     6901 atgtaactat gttaaagata ataagagaaa aaaagttaca gctatacata aggcaaatat
     6961 aatgaaaatg tctgatggat tgtttttaga tgtgtttaga gaagttgcat caaaacatgg
     7021 tgtagaatat gatgatttga ttgtagatgc agcagctatg aacttagttt taaatccaga
     7081 aaattatgat gtaatggtaa tgccaaatct ttatggagat atactatcag atttaggtgc
     7141 tgggcttgtt ggaggtttag gtataattcc aagcgcaaat attggtaaag attgtgcgat
     7201 atttgaagct gttcatggaa gtgctccaca aatagcaggt caaaataagg ctaatccaac
     7261 agcacttatt caatcatcag taatgatgct tagatactta ggtgaatatg aaaatgcaca
     7321 aaaaatagaa acagctttag aaaaagtatt tcttgaagga agtaaattga ctgtagattt
     7381 aggtggctca gcttctacta cagagtttgc ggatgaggtg tgtaagtata ttgtatagat
     7441 tttatttagg gaaaaagtga aatatagatt gaaggaaaga ggctttctca aaatagagat
     7501 aagccttttt ttattggaat gataaaatat atttgatttt atacaaaaga gagttcctca
     7561 taaacgaaaa agttaatttt gggatatcca ttttaatttt aaaattaatt gattaatacg
     7621 caaagaaaga ttaaacaaat ttattatttt taattgaact ttcaaccaaa atatggtaaa
     7681 atttaaaaaa gttgaacttt caactaaaaa taaatatatt gattatgtga aattctataa
     7741 aacagaaact atttgacttt agtcatggta ggttcagtgg aggtgtgttt gattaagact
     7801 ttagatagta atatattaag agaagtaggt actttatcta gagcagtaaa ttcaataaat
     7861 gatattaagt acaaggaatt aaagttacaa aaaggacaat ttacattttt gacaagaatc
     7921 tgtgaaaatc ctggtataaa tcttgtggaa ttatcaaata tgttaaaggt agacaaggct
     7981 acaacaacca aggctataca aaaactaata aaggcaggat atgtagataa aaagcaggat
     8041 gagtttgata aaagaggata taatttaact ccaactgata aatctttgga agtttatgag
     8101 ttgataattg aagaagagaa tagaagtata gagatatgtt ttgataattt tacagatgaa
     8161 gaaaaacaag tggtaactaa gttattagaa aaaatgagca aaaacgtaga aaatgaatgg
     8221 tttaaagtaa agagatagta aataaataca ttaacttaag gagatatttt tatgattaga
     8281 aaagcgaata tgaatgattt agaaagcatt atgaaaatta taaaatctac agtggaagaa
     8341 atgaagactt ataataatac acaatgggat gaaaactatc cattagaaaa agactttgtt
     8401 tcagatatta agaaacaaga tttatatatt tatgaagtgg atggagaagt agcaggattt
     8461 atatgtctta attatgaaga gccagaagaa tatttaggct taaattggtc atctaataaa
     8521 aaagcaatgg taatacatag aatggctgta aatccaaact ttagaaagac aggaatagca
     8581 tctaagttag ttgattttgc tgaaaaatta gctgtagaaa acaatgtatc atacttaaag
     8641 agcgatacat attcaataaa ctcaaaaatg aatttattac ttacaaagtg tggttttata
     8701 aaaatcggag aaatgagttt tttaggaaag gagaaatctt tctactgtta tgataaaata
     8761 ttataaagag catttataat acaaggggta aataatagat tttcagcatt agtaagggca
     8821 taatataacc cagtatatgc tattatgaaa gggatgattt atatgattgg atttctaaag
     8881 aaaagaagaa gtattagaaa atacaaggat gttgaagtag aaaaagaaaa attagataaa
     8941 atattaaaag ctgctctttt agctccatca tcaaaggggc ttagaacatg ggaatttata
     9001 gtggtagatg ataaagaaaa gctaattaat ttatctcaat gtagaactaa gggtggtgga
     9061 tttttcttaa aaaatgcacc tttagctatt gtaattattg cagataaaga aaaaaatgat
     9121 gtttggatag aggatgcaag tatagctgct tcatacatac aacttcaagc tcatgaacta
     9181 ggtttaggtt cttgttggat acaagtaaga aatagaatgt atgatgataa tatagaagct
     9241 gataagtaca ttagagaaga attaaaagta cctagcaagt acagtgtaga atgtataatt
     9301 tctataggat attctgatga agaaaagaaa gcatacaatg actctgattt agactataaa
     9361 aaggttcatt ttaacaactt ttagtatata atatgttgta ttaagacatt atattttttt
     9421 ctattgttaa tatatactta aaattgtaaa aatatatctg aattttacta acttatctag
     9481 gggttatgta caaggatttt aaagataaat atagaaatta atgtttataa tcgatacata
     9541 acttgagtaa caaaatttaa ggaggttaaa gtatgggtat atttaaaaca aaaatggatg
     9601 aggactggaa agtaaactac attaaagagt ttaatgaaat gagagattct tatgagagta
     9661 aacttcaaaa aaaacagttt gaggtagata gtttgaaatc agaattggat agactaagaa
     9721 gctataaaaa tagccttaag ccaaaagaaa aacaaattac tgatgatgat ataaataata
     9781 taaagagttt aagaagagat ggcttaagct ataaagaaat ttcaaatcaa acaagttgga
     9841 gcaaagcaac tgtaagtagg gtattaaatg gactttacga ttagcatata catggggtga
     9901 tttaaattgg gatgaagtat agttacaaaa aatgcataat agattctatt ttattgatgt
     9961 ttataattca aatattaagg atgattttga attatgtact tctaagtcaa tttgaattta
    10021 ctcttgaaaa ttttaatatt ataaacttaa tttcttttac attagttggt ttatcgttaa
    10081 ttttattttt aaaagataat tctttgtata acaaggttag aaatagaaaa atcacagaag
    10141 cttttgaaga aaataaaaac aatatactta ttgaaaagtg taagcttata ctttttgttg
    10201 tggttttatc tttagcaata attgtaactt attgtactaa gggatatgta ctttttaatg
    10261 taactatgat gactttgtct gtattgatag ttccaatatt tgaagagtta ttttttagag
    10321 aatatatatg gaactatcta agtaatttta taaagtcaaa gagtaaaatt atctgtataa
    10381 catctatact atctggaatt tataatatag gatacataga tgttataaga aattatgtaa
    10441 tattgtataa caattcaagc tacacctttg aagttattat ttcaaaaatt atgataggta
    10501 ctgtttttgg tattgtactt ggattagtta agtataggtt tagagatgta gggttttgta
    10561 tattattgag gagcttattt gctatattta ttaggtagat agtataatcg gtttataagg
    10621 ttgttttaaa tttaatttta aatcaacctt attttatttg tgttttataa aacacttata
    10681 tattaataac taataaattt aataaagatt atttgaatat ttttaaaata tataaatatg
    10741 tattgacata taaatattat gaattacaat ttatataaac taataaaaat taaataatat
    10801 taatcaactt attgaatgga ggaataaaaa tgaaatttgt gactttttgt agtagcaatg
    10861 aagaaaaaat aggtgtattt aattcagaaa caaatagtat atatgaaatt aatagtttag
    10921 gattaagtaa attatatact gatatgaatg attttattga aaacgtatct acaggagatt
    10981 tagaaaaaat aaaaaacaat tcatttgaaa acgcaaagtg ttataagtta gaagaagtta
    11041 aattatgttc cccaattgta agacctaaaa aagatattat atgtttaggt ctaaactata
    11101 aagaccatgt caatgaaatc ccagatggag ttataaaaaa cgtagttatg ccagattatc
    11161 caatttattt ttctaagaga gcagacaaaa taattggagt ggatgataag ataagcttac
    11221 atggagattt ggtagagaag ttggactatg aatcagaact tgcagtaatc ataggtaaag
    11281 aaggtataaa tatatcaaaa gaagatgctt atgaatatat atttggatat acaatagtaa
    11341 atgatataag tgaaagagca cttcaagata aacatgttca atggtttaga ggaaaaagct
    11401 tagacacaca tacatctatg ggaccttgta tagtacataa agaagaattt gaacatcctt
    11461 taaaattaga tataagtagt gtagtaaatg gagaagtaag acaaaattct aatacagagt
    11521 actttatatt tgatatacct actataataa atgatttatc aagaggaatg actctaaagc
    11581 caggagatat aatttcaact ggaactccag caggggttgc tatggggatg aatcctcaag
    11641 tatatttaaa gcatggcgat atagttgaat gtaaagtcga aggaatagga gttttaaaaa
    11701 atatagttga ttaatggata aatatgccat ataattttat tagtacaaat aatttaatta
    11761 atataggatt gatcaaactt atgattaatt tattatagag agggatgagt atatggcaag
    11821 agaactagaa ttaaagtatg gctgtaatcc aaatcaaaaa ccatcaaaga tttatatgaa
    11881 gaatggagaa cttcctatag aagtattaaa tggaaaacct ggatatataa attttttaga
    11941 tgcatttaat agttggcaac ttgtgaagga attaaaagaa gctacaggtc ttccagcagc
    12001 aacttcattt aaacatgtaa gtccagcagg agcagcagta ggggtacctt tatcagatac
    12061 tttaaagcaa atatattttg ttgatgattt agagctttct ccattagctt gtgcttatgc
    12121 aatggcaaga ggagcagata gaatgtcttc ttatggtgat tttatagcac tttcagatgt
    12181 atgtgataag gagactgcaa ctattatagc aagagaggtt tctgatggta taatagctcc
    12241 aggatataca gatgaagccc ttgaaatatt aaaaggaaaa cgtaaaggca actataatat
    12301 tgtaaaaata gatgaaaatt atactcctga gcctattgaa acaaaggatg tttatggaat
    12361 tacttttgaa caaggtagaa atgaaatatt aataaatgaa gaactattaa aagatattcc
    12421 aactgcgaat aaaattttta cagatagtgc aaaacgtgat ttaattatag ctcttattac
    12481 attaaaatat acacaatcaa attctgtttg ttatgctaaa gatggacaag taataggggt
    12541 aggtgcaggt caacaatcac gtattcattg tactagactt gcaggtaaca aagctgatac
    12601 ttggtatctt cgtcaacatc ctaaagtatt aaacttaaaa tttaaaaagg atataggtcg
    12661 tccagataga gataacacta ttgatgtata tctttctgat gattatatgg atgtgcttgc
    12721 tgatggcata tggcaaaact tttttgaaga aaaaccagag cctctaactg gagaaggaaa
    12781 aagagcatgg cttaaaactt taacaggagt agcacttggt tcagatgcat ttttcccatt
    12841 tggagataat atagaacgtg caaaaagaag tggggtaagt tttatagcac aaccaggtgg
    12901 ttctattcgt gatgataatg ttatattaac ttgtaataag tataacatag tcatggcatt
    12961 tactaaaaat agattattcc atcattaaaa tactgaaagt ataaagataa tatagattaa
    13021 gtaaaaatct acaacaagtt ttgttgtaga tttttttatt tgctgtataa ttttaaatag
    13081 aactttattt ttagatattc aatttggagg ttgatatggc tttaaatata agaaactata
    13141 gcctattatg taatcaagga acagctaaat ttaatgaaga tgtagtcggt ataaatccat
    13201 ttggggcatg ggttttagat ggtgctacag gacttaatgg aaaaaattta gtgtcaaatg
    13261 aaagtgacgc aaggtggtat gttcagtggt ggaataggta tttatataaa aatataaata
    13321 aagaagaatc attaaagagt attattaata ctggaataat agaagtaaaa aaagagtatg
    13381 aactaagatt aaatgggttt aaggttgaaa aattagattt accatctagt tctatagttg
    13441 ttgtaaaatt tcatgaaaat aaagtagagt attttttatt aggagattgt gctttgttta
    13501 ttaaaaatgg agattccaaa gttataaaag ataggagtat ttgtaaattt gataatactg
    13561 tatttgatga aatgagtaaa ctttctaact tggaagagat ggcatttgat gagattagaa
    13621 ctagtgttat ggatacaata gtaagcaata gattgaagaa aaatacgaaa gagggctatt
    13681 ggatattgga ttttgatgag gaagctgtgg aaaattctat atatggatac attgaaataa
    13741 aaaaagattt tcaattgatg ctaacgagtg atggttttac aagtgcatgt gatagatata
    13801 atctaataaa agaagaagaa ttgatacgta tagcagaaaa atttggtata ggatatatac
    13861 ataataaagt aagggatttt gaagataatg actataaagc ggttaaagtg ccaagattta
    13921 aaataaaaga tgattcatct tgtttatatt tagatatata taatgattag actgtataaa
    13981 actatttaat tttagaaagg aggcaagtga aaagtgaaaa ttcttcatat aataacacaa
    14041 aaaccaaata gtacaggtag tggtatatat ttgtctggta tgataaaagg gttcgaaaaa
    14101 atcggtcata agcaagctgt aattgcaggt atagatgtaa atgatgatgt aaattgtttt
    14161 ccaagtgaag taagttttta tccagtaaag tataattgtg gggagttaaa ttttcctgtt
    14221 gtaggtatga gtgattctat gccatatgaa agtacaagat ataaagattt aaatatagac
    14281 atgataaata gattgaaata tcaatttaaa gtaaatatag ataaggctat gaatgatttt
    14341 aaaccagaac ttataatatg tcatcatttg tacctcttaa ctgcatttgt tagggaaata
    14401 gtaaaagata taaaggttat gtctatttgt catggaactt gtttaagaca gttaaatacc
    14461 attgatttag agaaagaata cataatagca aatataagga aattagattt aatatttgct
    14521 cttcatgaaa atcagaaata tgatattata aagacttttg gagtaagtga aagtaaagta
    14581 gttgtaattg gtagtggtta taatgatgat atattttata ataaaaatta taaaataaag
    14641 gatgataaaa taaaaatagt atttgcaggt aagatatgta aatcaaaggg attgattcca
    14701 tttataaaat ctatatctaa attaaaatat agtaaagatt taatagaagt caattttgca
    14761 ggtactggaa gcgatatcga atcatataat gagatagtta aactggcaag taagtctcca
    14821 tttaaaatga atttcctagg aaagttagaa cagagagatt tagctgagct attcaacagg
    14881 tcacaaatat ttgtgttacc atcattttat gagggattac cagttgtagt tttagaagct
    14941 ttatcttgtg gcacagatgt aatcactact gatattcttg gtgttaaaga gtggattggt
    15001 agtgagatta ataattctgg aaagatagaa tatatttctc taccttttat ggagaaagaa
    15061 ggtattccaa aagatgaaga gttatatgat tttgaaaata atttgtataa tgcaatagat
    15121 tctaagatac aatctttatt gaataactca aatgagaaaa catctgtaga tatgtcaaaa
    15181 aaaacgtggg atggcttagc atatagaata aatgaagtta ttttaatgga tgaattgtgt
    15241 ttagtctaaa attatttaaa ttataaaaaa gtgtaactat ttttaaactt tttttaaatg
    15301 attttatatt atactaatac taaatatatt tgttttaggg aggtaattta tgaggattag
    15361 taaaaaggta ttggcgttag gtatttcagc attactgtta agtgttagtt ttccaacatc
    15421 aataaacgca ctagataaga ttgaaaatat tcaaggagta gataaatatg aaacagctgg
    15481 gcttatttca gataagcaag attttacaac agcagttctt atcaatgcag attctacaat
    15541 ggtagatggg attgctgcaa gtggtcttgc aggagtaaat aatgcagcta ttttattaac
    15601 taataaggat gatataccag aagcaacact tcaaagactg aatagagtta ctaagatata
    15661 tgtaataggt ggagaaaatt ctataagtaa agatgtagaa aaaatgttac ttatgagaag
    15721 aatgcaagtt ataagaattg atggtgtaga tagagtagat acaagttata aaattgcagg
    15781 tgaaatagaa aaaattaaaa acagtgataa gatgttttta gtaaatggat ttaaggatga
    15841 agctgatgca gtaagtgttg catctgttgc ttatagagat ggagctccta taatattgac
    15901 aaaagatata ccttcagcag aagaagacac agacttagac ccatggtttg gagtttctcc
    15961 tgttccagta tatgctattg gaggagagtc tacattaagt gattacatag tgagcagata
    16021 tagagcaact agaattggcg gtgttgatag atatcaaact aataaaaatg ttattgaaaa
    16081 gttctataat ggagcaaaag agttctatat aacaagtgga gacgatttag tttatgcttt
    16141 agttgcatca ccacttgcaa aaaatgctcc tgttgtttta gtttcaaata aaagtgataa
    16201 gagtatatta agtggagcta gtaaagtaac agcaataggt ataagtgata agagtattat
    16261 agagcaatgt ttggatgctg taaagaagta atggagtgtt attagtaaaa tgaatatata
    16321 cattgaaaat tagtagattg ttcattttat aatggtataa aatatatggg aagaggctat
    16381 caaatggaga taagcctctt ttttattgat aaaattatga aaatatactt tattttatat
    16441 aaaaaaagta tctcatgaac taaatgtcta ttttgatata ctatctcctt ttcttatatt
    16501 atatgtatta tatgattttt tatatggaat aaatttcata agtattatct tcctttaatt
    16561 tttctaacca aatcatctct aaaatatcta gttcttctaa atagtctttc tctgttttgt
    16621 tatcatcatg ttttataagt tctaaaactt caaatgtaaa tgctttttca ccatattttt
    16681 tccattcatt atttaattct tttatcatac atgagccagc accaagctga aatttgagag
    16741 agttaaattt gctttttatg tcattacttt ttccaaggta aatcttttta gtaatatcat
    16801 tttttattat gaatacacct gtgtcaaatt tcatttcttt gtataattgt tttaattcac
    16861 gttttctatc catgatttta gatacctctc tttataattg atatgtaata tgtaagttta
    16921 aaaatatatt acatatcaat tataaagaga ttaattttat atgtaaatag tttttataaa
    16981 tttaattatg aattagtcat caataaacaa gaaatttagc tgtagaaatc cattataaag
    17041 gctattataa attttaatat gctaaaaata taaaaagaat agttgacagt atagaaaata
    17101 tggaataaac taaaagtgta atagtaatac gaaattatat attacattga aaggtgtgaa
    17161 tgattattat gaataaaaaa atagaattaa tagggaattt tgcaagtgat tggattaggt
    17221 atagtgatta tgaatataaa attactgaag aagatgaatt atatatagtt ccaacagaag
    17281 atgctgtgtt taccatgtat aacccatttg atgtagcaga tgatataata gtagatataa
    17341 ttcgcatagg acaagaggca ttacaagata tatcaaaaga gacaaaagaa atgaaactaa
    17401 agaaagaagt acttgaattt gtaaaaaagt atggattatt gggtttaata tattcaagtg
    17461 tatataatag agatatagtt ggagaagaaa gagtactgat gattgaaaag aattatatta
    17521 caaaagagaa tatattgagt acagatgaat atgtaaacat gtttatacca tttgcaagtg
    17581 atgaagatgt gtattttaaa aaatatagaa ggggtataga tgtatcaaag agagaagaat
    17641 ctccaaagtt ttttggaaag agaccattga ttttagattt agtattttca aagttctaca
    17701 ctgaacaact agattggatt gtaagttttg ctaaagatat gtgtaagcat tttaatcaaa
    17761 tttgtgtata taaaaataca tctaatctat taactgaaag tgttactatt atgtctggag
    17821 ggtttaatcc tcaaaagata ggattttcta taagccaatt agataaacca attattgcat
    17881 gggagtttga ttctttgaaa acagctattg agactatcta tgcctttgca attacaagtg
    17941 aaccttcttc tttaaataaa tgcaagtact gtggtaaaat ttatattcct acaaattcta
    18001 aatctcaata ctgttcacct tcttgtagaa attgctcaaa tgtaaagaaa agtagaagta
    18061 gagccaaaaa agataaataa aattaataaa tatatcattg tttagatttt agtaaataac
    18121 tactgaatta aaagttgtta tagaaaatta tatatctaaa tgatggtatt tttttgttga
    18181 gaaaattgaa aagtttaatt gagatagtaa ttttgagttg acaaaaacca cttttaacac
    18241 tactattata agtggttggt aaaataatat acactaattt aaatatagca taaaaaacaa
    18301 aaaaagtcaa tgaaaaaaat aaaaaaggag aatttaaaaa tgatatcacc tattattttg
    18361 agttctataa atcagaattt aaaggaaata gaaagaaatg aactgcttga aactaatata
    18421 gaatctggag attatggtct agctctttct gaatctgatg taaaagatat aataaattcg
    18481 agagataata ctttaaaggg gtatggaaga atagaattag atataaaagt tacaaaacag
    18541 ttaatagaaa atatatatac atcacaatat acaaatgtgg acaattattt agaggctatt
    18601 aatgatatgc aagaaatttt ttattattta aaaaatgaaa ctgatgacaa gatatgtgat
    18661 gatgagatta tagaaatact gggtgaattt tatgaaaaat tttcaggcaa tatggacaat
    18721 gtaagaggag aagcagacga atttgcaaag aaatttaaat ttggagaagt ttaatatatg
    18781 ataggagaga ttttgtatgt taaataattt aagtaatatt aatataaacg aaaataattt
    18841 aataaagaac caatattcca tatctctact taaggaatgt ctaaattgta aagtgataga
    18901 tgaaagagaa gtatataata tacaacaaga aatatctcta atacttatgg atttgattaa
    18961 aaaatataca aatggtcaaa gcacatcagt aaaaacagaa gttgccgaaa aactgttgat
    19021 ttcaatatgg tatgctattg atgcatatat aaataagctt ggagatatag aaaaaagagt
    19081 tgtggagttg actgctaaga atgttaaaaa agtgtacctt ggaggcattg aaatattaga
    19141 ggaagagtta gttaggctga aagattttta taaactaatg atgagtagaa aattggatac
    19201 taattcaata gcatataatg ataccttgat ggagttatca agtttcttta aaagttatat
    19261 tgtaaaattt gaagctcagg acgttccagt aagtatagat tatccattgg cactagatga
    19321 tatggatgtt aagggtattt attatgtgaa gaattatatt gagagtatag atatagaaaa
    19381 tagattttgt aacctattta agaaaaaaga tagagaaaaa ttattttatg actatggggt
    19441 gatttataaa atagattgtg atgttatact tgtaaattta tttgaactta ttataaataa
    19501 ttgtattttt tctactattt taggaaatga agtgattaat ttagaaattt caaaatatga
    19561 gtatgaattt ttagaaaaac aatttaaaaa tatgtacaat aatattactg aagataaagt
    19621 tataggctct gaagaaagta atataattga attgattgaa gtagatgata gttttaacac
    19681 tgaagtagat agtaatttgg attataatga ttttgaagaa attaacagag aaattagaat
    19741 aaataaaaaa ataactttac tacttatgga agcaattgaa gtattaataa aaagattaag
    19801 catagaagat gaagatgtaa taagatatat taaaaaatat gaaaagatat ttattgaatc
    19861 tgtgctaagc tcaataaaaa gtaacacttt taaaagtatg gtaactgtga gtaaaaataa
    19921 aaatgaacac ttagaagact atattgttga tgatgaaagt aaattggatg atgaatcgtt
    19981 tagagagata ttcaatgaga tattagatag tacatctata attgaaaaaa taagaataat
    20041 aaaggaaaat atcaatgcta aaaaagactt tatcgatatt cttgaatctg aatgtttatt
    20101 tggagaagag tatttaatgt tgtttgcatc attaagtgaa ttagaattgg caatattggg
    20161 tagtgtagta ttttatgaag atattagaat gagagaaatt aatatattag aatttatgtt
    20221 aaatgagaaa actgaaacta ctttatggaa gacagagtac attaaattta tgaagaggca
    20281 aagtgaagat aagatatact ccatagaaga gcatatgaat aaaattaatt aacaaaaaat
    20341 tgtgaataaa tagaatgtta gtatataata taatctgtaa agcatatcaa aaatacatat
    20401 atttggagga aaattatgaa agagtatatc ataaataatg ttgaagaaat aagagaagaa
    20461 ttaattgatt tatctaagaa aatatgggaa aatccagaat tagcctttga agaaaagtat
    20521 gcaagtagca ttcaaaaaga atacctaaag tcaaaaggat ttaaaattga agaagtagaa
    20581 aatttaccta ctggatttat agcaagtttt ggagagggta aacctgtgat tggcatactt
    20641 ggagaatatg atgctttacc agagctatca caatgtgtga gtgcagaaag aaagccattg
    20701 gtagaaggaa aagctggaca tggatgtggg cataacctgt tgggtgtagc aggtgtagga
    20761 gcagttgttt ctataaaaaa attaatagaa gaaaataaat ttaatggaac aataaaatat
    20821 tttggttgtc ctgctgaaga agaaggtgga ggaaagacag ttatgtgtat aaatggctgt
    20881 tttgatgatg tagattgtgc atttacatgg catccttttg atataaatgc accttggaga
    20941 ggtggaagtc tggcaaactt atctgtaaaa tttaaattta aagggataac agcccatgca
    21001 gctcaagctc ctcataatgg tagaagcgca cttgatgctg ttgaaattat gaatgttgga
    21061 gctaattatt tgagagaaca tgttattgac tctataagaa tgcactatgt tataactaat
    21121 ggtggtggaa gacctaatgt agttcctgga tttgctgaaa gttggtactt tattagaggt
    21181 aaaaaagcaa gggatgcaga acatgttctt gatagattaa taaaagtagc tcaaggagca
    21241 gcaatgatga cagaaactga aatggagtat aaggttacag atggaatata tgactatata
    21301 ccaaaccaat gtttgactga tttagtttat gacaatatgg tttttgttgg ttgccctaaa
    21361 aatactcctg aagaagaaga atttgcaaaa aaattgtgtg atactcttac tagagaagaa
    21421 agattaggtg tagcaacatc attacaaaat gataaatcta ttgtagaaag ttatatacac
    21481 aaggaaatag ttgacggtga caaagataaa ggactagctg gttctactga tgttggagat
    21541 gtaagttatg taataccagt ggctcaattt gcaatggcag cttggcctgt tggaattgca
    21601 agtcatacat ggcagtcatg ttcatcagca ggttcaaata taggattttc tgctatgata
    21661 aattcagcta aagtactggc ttgtagtgct tatgatgtat ttatgaatac taaaattatt
    21721 gatgaagcaa aaattgaatt tgataaatca ttagatggac aaaaatttaa accattggta
    21781 taattttggt aataaaatat ttctgggggg aatagctatg agagaaaaag ttgaaaaagt
    21841 gcttgaggaa aagataaaac cagtattaca aagagatggt ggagatgtag agcttataga
    21901 tgtaaatgaa aatggtgtgg ttttagttag actacaaggg gcatgtagtg ggtgtccagg
    21961 agcgactatg acaatcaaag ctattattga aaatgttttg gtgagtgaag ttccaggagt
    22021 aactcaagta ttaggtgttt aatagttagc gtttattaaa tgtatgttat acataagtat
    22081 ttaataaaga agtaaaaaaa atagtgaagc aatatatatg aaaaagtatg ataaagataa
    22141 taaaacatta tagaaataat gaaatatttc atatgtatat gaagaaataa gaaaaaatag
    22201 tgaagcaata tatatatgaa aaagtatgat aaagat
//
LOCUS       DAMJYN010000063        22146 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.064, whole genome shotgun sequence.
ACCESSION   DAMJYN010000063 DAMJYN010000000
VERSION     DAMJYN010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22146)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22146)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22146
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.064"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            577..1884
                     /locus_tag="PC466_002600"
     CDS             577..1884
                     /locus_tag="PC466_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769967.1"
                     /translation="MKEIADAITSEYLSYGINEDISIYEGRFCIYLDKKYRCNGKIYY
                     KMTPPISISFKADIGCVEEIDNEDDNLVLDYDNAILEVHGYKIISITINTLSEFSVEG
                     YINDDCIKSKNSYVEYVDFNIINLDKIPGKLIKYNDKVYAGRIEFDINDYVVTIDKRY
                     DYRKELKSELKSKSGAIITHIGRIRRKDGRIFRTNNTINLLDRISTALSFMCGRYVGF
                     CLAKGYRSGNEVYRIWNENQISPFRYVPTWSDTLSNYHNMEKYISLMCKKLEDFYYGS
                     AIKSVVDWYIESLGSATMENNIISVQIALETLSYVILVEQSKILTDEAFDCNLASKNI
                     RLLLDTCKIPYGKHELNIFDNIIKNKFDDGVDLVIYLRNSIVHPSRKTHRAVLEVEDI
                     WNIISIGTRYIELVLLFILGYRGEYSNRLVERCYGEVEVVPWN"
     misc_binding    1970..2232
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            2358..3161
                     /locus_tag="PC466_002601"
     CDS             2358..3161
                     /locus_tag="PC466_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HDF2769968.1"
                     /translation="MKNILKKVGIFTIMLGLLGGVVGCSKPDNEKDKDASKESKKEVV
                     VGFDNTFVPMGFLDEKGDTVGFDVDLAKETFKRLGMEVKFQPIDWSMKETELNDSKTV
                     DVLWNGYSITDERKKIVSYTEPYLQNKQIIVTLSDSKINSKADLKDKEVGTQQGSTAL
                     DAVEKDKDFMNSLKGGAPVLYDTYDKALRDLEIGRTSAVVGDEVLIRYYMGQKGEDKY
                     KVLKDDFGLEDYVVATSKENPELCEKINKTLKEMKKDGTFDKIYDKWFK"
     gene            3199..3810
                     /locus_tag="PC466_002602"
     CDS             3199..3810
                     /locus_tag="PC466_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HDF2769969.1"
                     /translation="MLQGLEIVIAMFCITLIVSIPLGIGVAFLRLSKNKLVSGITQCY
                     ILIMRGTPLLLQMIVIFYGLPLLGIVFDRFTAGVVAFFLNYAAYFAEIFRGGIQSIDR
                     GQYEASKVLGFDKFTMYKRVIFPQVFKRILAPISNEVITLVKDTSLVYILGLNDILRI
                     SQIAMNREASLLPLFEAGAIYLIFVAILTKGFELLEKKYSYYR"
     gene            3842..4513
                     /locus_tag="PC466_002603"
     CDS             3842..4513
                     /locus_tag="PC466_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HDF2769970.1"
                     /translation="MLKIKNLNKSFKKNRVLKDISFELEEGQIGVLLGKSGAGKTTIL
                     RCINGLEEFDSGEIIIDNEVIKNKRDMAKIRGKIGMVFQNFNLFPHMTVLENIIESPV
                     NVFKVPRKEAEERARELLRLVDLEDKLNSYPFELSGGQQQRVAIARSCALMPKVLCFD
                     EPTSALDIDTIQRVVNIMNRLKDKGMTILIITHDVVFSNNVADKIISIKDGIVENVQI
                     KEKIV"
     gene            4812..5174
                     /locus_tag="PC466_002604"
     CDS             4812..5174
                     /locus_tag="PC466_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HDF2769971.1"
                     /translation="MIKLYGYTKCSTVKKAKNWLKENNLEFEDIDMVQNPPSKEELKS
                     IYKTSGYDIKKFFNTSGMKYRELGLKDIVKTESDDKLLEILVSDGMLIKRPLLLDGKN
                     VLLGFKEDVWKSTLLKED"
     gene            5610..6311
                     /locus_tag="PC466_002605"
     CDS             5610..6311
                     /locus_tag="PC466_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4253 domain-containing protein"
                     /protein_id="HDF2769972.1"
                     /translation="MSIEDLYDFECVPLNNEIDIDVLFEKMIEDGKEKEYTPIIVIDE
                     KVGLLRKNIDMITKEYGSLENYREYCLTKYNEIDVNQFFDFRKSEISELLKELIDLED
                     DFYDYKHFRPIINIDIFHEYNKVYIAKIPTIKPYEVFAYIPIGGFNDCPRDEEHIAIA
                     KYWYEKHGIFPIAIGCDTVQYSVKNLTKDGKKFDDLCIELVFYCEDIIIQGYETLKAL
                     KDVLKRSTIVLFWWD"
     gene            6582..7400
                     /gene="larE"
                     /locus_tag="PC466_002606"
     CDS             6582..7400
                     /gene="larE"
                     /locus_tag="PC466_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent sacrificial sulfur transferase
                     LarE"
                     /protein_id="HDF2769973.1"
                     /translation="MEVNFVKEKEKLDKLKKMLLELGSVVVAYSGGVDSNFLLKVAKD
                     TLGENVIAVTIHAMMHSSREIEEAKQYTQNFGVKHIILNIENFDLKEFKENGVDRCYH
                     CKKYIFSKIKEVAKEHNIKYIVDGTNMDDLGDYRPGLKALSELGVISPLKDSSLKKEE
                     IRSLSKILGLNTFNKPSFACLASRIPYGVEITDENLRIVEKSEEYLFNLGFSQFRVRM
                     HGEIARIEVGQEELGKFFENNNFNKVDTKLKIFGFKYVTLDMSGYKMGSMNLNV"
     gene            7455..8603
                     /locus_tag="PC466_002607"
     CDS             7455..8603
                     /locus_tag="PC466_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HDF2769974.1"
                     /translation="MKNYTLISPCFFGMEKMLAREITNLGYEIIKTEDGRITYKTDEF
                     GIAKSNMWLRCAERVHLKIAEFEAKSFDELFENTKRINWSRYIPYGAQFPISKASSIK
                     SKLYSTPDVQAIVKKAIVESLKKSYLEDGLLKEDKEKYPIFVFIHKDKVTISIDTTGD
                     ALHKRGYREKANKAPIRETLAAGLIYLTPWKAGRVLVDPMCGSGTILIEAAMIGINMA
                     PGLNREFISEKWRTLDKKIWWDVRKDAFNKIDNESKFKIYGYDIDEESIDIARENAEI
                     AGVDEYIEFNVGDATQFKSEDEFGFIITNPPYGERLEDKDSVKQLYKELGYAFRKLKN
                     WSYYLITSYEDFEYEFGQKADKKRKLYNGMLKTNFFQYPGPKPPRNNK"
     gene            8739..10127
                     /locus_tag="PC466_002608"
     CDS             8739..10127
                     /locus_tag="PC466_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769975.1"
                     /translation="MKVLKLITVVALMMLFVTGCNIKTESPEQLAKIPDYDDTKKVLY
                     DGIDQLLKPDSSMILPSNTKEVGKINKVDLNSDGIDELVVFEQKEDLSNNVSQVGFVT
                     LSYNGEKYVLGDHFLENGESIEYANFYDLDSDGYKEVILLVKSKDKTNMHIYKVVDNE
                     ITKIYDLDASWLQNKEDFNDMKVKIGYIDGDDKLDILMLHLNNKTNEMFASVANFDGK
                     MKIKDSVKFENVKNLSELYTTLGNVASSVGNSSAAIKGIVLDIPILKDNNYITQILYM
                     KDGKINKAFSDYDKTITKSYYIPVDDIDKDKIIEIPIVAGSTGNNKNTYSSKSSATIS
                     WYRWNGKEGADSSLIFTSQIYYNYKYNFKLFIPNNLFDKILVEQEFVGEKAVFKFYYF
                     DYSDRKNLFNIVVESKNKLEDRKNTGTQNSIVLQESDEYTFLLVVNNANEMDKLDMTI
                     DALKEYFSLIYG"
     gene            10156..10854
                     /locus_tag="PC466_002609"
     CDS             10156..10854
                     /locus_tag="PC466_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2769976.1"
                     /translation="MKEKILILEDEIGIRSFVSINLKREGYEIVEAGTGREAIEKMTT
                     ENDITIALLDVMLPDISGIEVCKFIRENFDQVGIIMLTAKAQEDDKIEGFISGADDYI
                     IKPFSIKELLVRVSALLRRVAKDDSSVKSSEIVSPPFILDIDKRKLFKNGKEIELTPT
                     EFSIVKYLISNAKQSLSRDQILDEVWGTNYLYDFKIVDVNIRRIRNKIEDDPSKPKYI
                     QTIWGYGYCFRKEE"
     gene            10857..12290
                     /locus_tag="PC466_002610"
     CDS             10857..12290
                     /locus_tag="PC466_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2769977.1"
                     /translation="MLHFEGLRKKVIKNYFIIIIIMVTLFEGLFMFYIQNYYYDSVKQ
                     LLESEIKYADEYNAITMETTSFEKKVKNIFDKQPLTKNSEFGISIIDKDKNIILDQYG
                     FKSKEKANYEDVNNALKDIKTKNLTPYTYRIPDTGEHVMSISLPLKVNNIIEGVVRYT
                     VSLDAIDNAILKQATWLILAGIFILIIAILISLKFAETLIKPLRELKKFANELAVGNY
                     NIKLEKMKIVDDEIGDLAQTFEHMAHEIDKSEKLKEEFISSVSHELRTPLTSIKGWSE
                     TLGYESITREELDLGLGIIQDETERLIKLVEELLDFSRLSSDRIKLHVDIVDVEGLIV
                     GVVNQLKVKAAEKDISLLFEFENEFIENIQGDKNRLRQVLINLIQNSFKFTSQGGYIK
                     VVASQDEEITTISVEDNGSGIEKQNLNKVLDKFFQEDYNKAGSGLGLAISNEIVKLHG
                     GRMKIESEKNVGTKITFNIKNKFAKQA"
     gene            12312..13049
                     /gene="truA"
                     /locus_tag="PC466_002611"
     CDS             12312..13049
                     /gene="truA"
                     /locus_tag="PC466_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011010156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HDF2769978.1"
                     /translation="MRNIKMIVAYDGSRYKGYQKLGDNNMTIQEKLENVLSKMTNETV
                     EIIGSGRTDMGAHARGQVVNFRTNCMDSLDKIQKYLYEYLPEDIVVKTVEEVDERFHS
                     RYNVKSKTYMYKIDNNKYHNPFIRKYATHVSKKLDLDRMRKASEYLVGEHDFTSFASS
                     KSKKKSNVREIYSINIKEDDNVIEIYVEGNGFLYNMVRIIVGALIDVGLKRRAPQDIK
                     YMLESKDRCQSSDTAPAKGLCLWKVTY"
     misc_binding    13160..13367
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            13620..14819
                     /locus_tag="PC466_002612"
     CDS             13620..14819
                     /locus_tag="PC466_002612"
                     /EC_number="6.3.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HDF2769979.1"
                     /translation="MKEKVVLAYSGGLDTSIIIPWLKENYEDIDVIAVCGNVGQEDKM
                     EDVYEKALQSGASKAYVDDISEEFVTETIFKAVKAEAKYEGKYLLGTSLARPIIAKKL
                     VEVAHKEGAKYICHGCTGKGNDQVRFEATIAALDPTIKVIAPWRIWDIKSREDAIDYA
                     EKHNIKVTATKAKIYSVDANLWHVSTEGGDIEHLENEHKKDVYKQCVDPEDACDVAEY
                     VEVYFEKGVPKKVNGEELSPVALIHKLNELGCKHGIGVIDIVENRLVGMKSRGIYETP
                     GGTILYEAHNILESATLDKDTLHFKQMVSYKYGELIYNGLWYCKLRESIDAFMEQTQD
                     NVTGTVKVKLYKGNIKPAGIFTENALYDEGISSFGNSELYDHKDAEGFINLFTLPLKI
                     RAMKAGK"
     gene            15066..16112
                     /locus_tag="PC466_002613"
     CDS             15066..16112
                     /locus_tag="PC466_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4872 domain-containing protein"
                     /protein_id="HDF2769980.1"
                     /translation="MRKIIEIKHHSHDYECMWNGIEDLYINKTGECLPNDFFFLLSGF
                     GSFCYMKTNKADLKRMVALGDGRTKQMYKFLAPIVGFEYKHHEFKKYEQALKKAKSEI
                     DGGYPVILGALDMYYLPYYKKLYHKEHIPFHYILMVGYDDERIYLYDCGRTELLHLSY
                     DKLRESMNCNSPGLSKENTICTIRMNTSKNKYNIAREAIAIKRDMFLNPSKGFLGYKG
                     FEKFIKELPQWNTELDKDDYDKILTNMVMFFGTVPTIPNAIKGIKEPDTVQFKGGFDK
                     MSRMLNSIGEEYKNDSFIQVADIFDKTAIIIEKISNIIIDYLTQTCDDTEQLPLLFSE
                     VLEHMKTGYLILDV"
     gene            16220..17383
                     /locus_tag="PC466_002614"
     CDS             16220..17383
                     /locus_tag="PC466_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF2769981.1"
                     /translation="MRTVKQVSDLTGISVRALHYYDEIGLLKPNKITDAGYRLYDDES
                     IKTLQQILFFKEIDIPLREVKEIMSSQYFDKVEALKNQKKLLILKRKRLDELIELINQ
                     TLRGEGNIDFKEFDMSEYFNVLEEFKREHRNKIIKIYGSVEKYNEYIERVKSNEEKIA
                     KMAIKQYGTIEKFAQAIKTNFSSDILNLGEKFDRYKNDCLKEKHPKLKELYRKLVEDL
                     SKNPSSTDLQEIAKEITDISKKDYEIFSMYTGDDNWYYMIQNYLVNPMWIEEVDKKYG
                     SGAGKFIGQVLKTYLRDRKPKINTLYEKLVEDLSRDCSSREVQSIVEEIDNEMKRSNE
                     FYKIDNGERYFDYMSELYLQDSNYIKVTDKNYGDGASKFIGEAFKIYFDNNNC"
     gene            complement(17472..17852)
                     /locus_tag="PC466_002615"
     CDS             complement(17472..17852)
                     /locus_tag="PC466_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4363 family protein"
                     /protein_id="HDF2769982.1"
                     /translation="MKSTTFVILWTILFVLFGFYVNNKLYDFTEGYKDNISVLEKSIE
                     NEDWEKAQKEADSISTSWNKEKNHWYKVLNHEYFDEIGLRFNILDKAIYTENKLKSLE
                     EVESIKTYLGNIIESVKFDVNYIF"
     gene            complement(17855..18514)
                     /locus_tag="PC466_002616"
     CDS             complement(17855..18514)
                     /locus_tag="PC466_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HDF2769983.1"
                     /translation="MTVVLIRSIILYITVLIALRVMGKGEIAEMNCFDLVITLLIAEV
                     ASVPMENNNIPIINGVAAISGLVIMQTLISFLSLKSRKLSSFLSGKPSVLIDKGKIVY
                     KELKKERISIDELLEQLRIQGYFNLKDVQYAILETDGNLSVVPASSYNSTPPRAFNHL
                     PIPLILDGRIINKNLDIAQKDTNWLMGILKSNHIETFKDVLICVLDENDKIFIQNKKG
                     D"
     gene            complement(18620..19594)
                     /locus_tag="PC466_002617"
     CDS             complement(18620..19594)
                     /locus_tag="PC466_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HDF2769984.1"
                     /translation="MKYKLFIDFEFNILDDNKNKPKEYNGAELISIGGVLVDNEFNTI
                     DNYYSLVKPKYNKILSNKCKNLTKLNQLDINNAPNLLYVMDDFYKWFCKFDDVTIYNW
                     GDFDITGLLTSFRVYKYTGKCLELFNMMIDIQPFISQHITYNNRILSKQISLLNMKKI
                     FSVEGDIKHNSLSDAVDLMNVCKCFFFNSPKNIDILEELYNKLPALKTPLYYIPYFED
                     ENFELKFDRTPEDIIIYLKQILTILNISKKEIYFKKRSVLVNNSKIINFKNLSSSFKL
                     IKLNEFEEYPDFILKLGDKKSFVESVIKINKSNRKSIKNLILKLSKKP"
     gene            complement(19634..19981)
                     /locus_tag="PC466_002618"
     CDS             complement(19634..19981)
                     /locus_tag="PC466_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769985.1"
                     /translation="MLNLKEIREEIIKKYIGDSLISELTEELKNILITDLQSNPFKSN
                     IELSIIPANIEIFKKIENILIDSKVNLKMGWERILINYILKDLFELNYEINKSCNEPL
                     MFRVIISIDSYDA"
     gene            complement(20199..21155)
                     /locus_tag="PC466_002619"
     CDS             complement(20199..21155)
                     /locus_tag="PC466_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HDF2769986.1"
                     /translation="MKKILITGALGQIGSELTIKLRNEYGEQNVIASSRRVKEGNPVC
                     ESGIFEILDVTDKNRFFEIAKKYDVDTIIHLASLLSAVAESKPLEAWNLNMNGLINGL
                     EIAKELDCKFFTPSSIAAFGENSPKNMTPQDTLQRPNTIYGVTKVSGELLCDYYHSKF
                     GVDTRGVRFPGLISYVTPPGGGTTDYAVDIYYEALKNKRYKSYIAEGTKMDMMYMPDA
                     LQSIVDLIQAPADKLIHRNAFNITAMSFSPEEIADSIKKYIPDFVIEYDVDPVRQSIA
                     DSWPNSLDSSSAVKEWNFKFSYDLDKMTKDMLEKLSEKGIGK"
     gene            21596..21964
                     /locus_tag="PC466_002620"
     CDS             21596..21964
                     /locus_tag="PC466_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C-GCAxxG-C-C family protein"
                     /protein_id="HDF2769987.1"
                     /translation="MTRPSIYHSQGYTCAEALIKSYNEEHNTDIPISIGSGMGVGMNV
                     GSVCGAVNAAVVIIGYLNGRNSNLDENIARKYSRELLNKVRNKYSSEICVSLKKNKVT
                     CEEIINFTYDALNDMLKNQK"
BASE COUNT         8783 a         2233 c         3653 g         7477 t
ORIGIN      
        1 ataaaacaac aatggtgcta atttatatgt ataaattaat tatgaaaaat ttatataagt
       61 aaaatatatt aacataaagg taaaattttg tatactaaaa gggaatattt acagtttaat
      121 ggcagtttta aaataataaa ttaaagctgt catttttatt taaaaatttt tagaaaaagt
      181 acaatagtgt taatgtgtga attagataag gtgtatataa taatttagat gatatgatat
      241 aaaatatgtt gtaaattaaa tgttttcttt gacaatatat acacaaggat gataatatct
      301 atatgaataa aagatagtgt gtaatttgat aatatgtaat tataacatta tgatataatt
      361 acaataaagt atgtaataat ctgtagaaat ttcaagctag ttatctaagt tttcggataa
      421 ctaaatctaa acggaataca taatgtatta aataaatgat gatactaaaa tgatactatt
      481 tttatagaaa tttattgagg tatataattg atgaaaataa tatattaaat tatataatat
      541 attgagtttt acataaaagc gaaggtggga ataaaaatga aagaaattgc tgatgctata
      601 acatcagagt atttaagcta tggtatcaat gaagatatta gtatctatga aggtagattt
      661 tgcatatatt tagataaaaa atatagatgt aatgggaaaa tttattataa aatgacacct
      721 ccaatatcta taagttttaa agcagacata ggttgtgttg aagagataga caatgaagat
      781 gacaatttag ttttggatta tgataatgct attcttgaag ttcatggata caaaattatt
      841 tctataacaa taaatacttt aagtgaattt agtgtagaag gttatatcaa tgatgactgc
      901 ataaaatcta agaactccta tgttgaatat gtagatttta atataataaa cttagataaa
      961 atacctggaa aactaattaa atacaatgat aaggtatacg caggtagaat tgaatttgat
     1021 ataaatgatt atgttgtaac tatagacaag cgatatgatt atagaaaaga attaaaatca
     1081 gaattaaagt ctaaatctgg agcaataata actcatatag gtaggattag aagaaaagat
     1141 ggtagaattt ttagaacaaa taatacaata aatcttttag atagaatatc aacagctttg
     1201 agttttatgt gtggaagata tgtagggttt tgtttggcca aagggtatag aagtggtaat
     1261 gaagtttata gaatatggaa tgaaaatcaa atatctcctt ttagatatgt accaacatgg
     1321 tcagatacac tttcaaatta tcataatatg gaaaaatata taagccttat gtgtaaaaag
     1381 ctagaagatt tttattatgg ttctgctata aagagtgttg ttgattggta catagaatct
     1441 cttggaagtg ctaccatgga aaacaatata atatctgtac aaattgcact tgaaactttg
     1501 tcatatgtaa ttctagtgga acaaagtaag atacttacag atgaagcatt tgactgtaat
     1561 ttggcatcta aaaatataag actcttactt gatacatgta agataccata tggtaaacat
     1621 gaattaaata tatttgataa tataataaaa aataaatttg atgatggagt ggatttagtt
     1681 atttatttaa gaaatagcat agttcatcca agtagaaaga ctcatagagc tgtgttagag
     1741 gttgaagata tttggaatat aatttcaata ggaacgagat atattgaact tgttttactc
     1801 tttattttag gttatagagg agaatattca aacagattag tagaaaggtg ttatggtgaa
     1861 gtggaagttg taccttggaa ctagattttt atatttattt taaaatatat attgacatat
     1921 attgccttat gctataaaat caatatcata ataataattc agaataacat taaatgctaa
     1981 gaaaagaaat agtaaaggta gttaatctta aacagagagt ttccgattgg tgagaggagc
     2041 aatagatttt actttgaaca catctttgag caggactctg aaagagtaga aatactttat
     2101 taggagattt ccggaatcct tgcacccgtt atagtgctag agtataataa ttttattgta
     2161 cttaaagagg ttagtgtcgt gaggcattaa tgaacagagg tggaaccacg agagttaact
     2221 cccgtcctct agcagaagct agaggcggga gttttttaat ataatttttt aagcgcgcag
     2281 agaattatat tgcaatagat acacttttta aaaaataatc aaaatatttt aaaaattaaa
     2341 aggcgaggga gaatattatg aaaaatatat taaaaaaagt aggaatattt acaattatgt
     2401 taggtttatt aggtggagtt gtaggttgtt caaaaccaga taatgaaaaa gataaggatg
     2461 cttcaaagga atctaaaaaa gaagtagttg tagggtttga taatacgttt gtaccaatgg
     2521 gatttttaga tgaaaaggga gatacagtag gatttgacgt agacttagct aaagaaacat
     2581 ttaaaagact tggaatggaa gttaagtttc agcctataga ttggtcaatg aaggaaactg
     2641 aattaaatga ttcaaaaact gtagatgtat tatggaatgg atattctata acagacgaaa
     2701 gaaagaaaat agtatcatat acagaaccat atttacaaaa taaacagata atagttactc
     2761 taagtgattc aaaaataaat tcaaaagctg atttaaaaga taaagaagtt ggaacacaac
     2821 aaggttcaac agcacttgat gcagtggaaa aggataaaga ttttatgaat agcttaaaag
     2881 gtggagcacc agttctttat gatacttatg ataaagcact tagagattta gagataggta
     2941 gaactagtgc agttgttggt gatgaagttt taattagata ttatatggga caaaagggtg
     3001 aagacaaata caaggtatta aaagacgatt ttggattaga agattatgtt gtagcaactt
     3061 ctaaagaaaa tccagaactt tgtgagaaaa taaataaaac attaaaagaa atgaaaaaag
     3121 atggaacttt tgacaaaatt tatgataagt ggtttaaata gaagataagt tagctgttaa
     3181 gaagggggca ctaaaggcat gttacaaggt ttagagatag ttatagcaat gttttgtata
     3241 acattgatag tatcaattcc attggggatt ggagttgcat ttttaagatt atcaaagaat
     3301 aaattagtaa gtggtattac acaatgttat atattgataa tgagaggtac acctttactt
     3361 ttgcaaatga tagtcatatt ttacggatta cctcttttag gaattgtatt tgacagattt
     3421 acagctggag tagtagcttt cttcttaaat tatgcagcat attttgcaga aatatttaga
     3481 ggtggaatac agtcaatcga tagaggacaa tatgaagctt caaaagtact aggatttgat
     3541 aaatttacta tgtataagag agtaatcttt ccacaagttt ttaaaagaat actagcacct
     3601 atttcaaatg aagtaatcac attagtaaaa gatacatctt tagtatatat attaggatta
     3661 aatgatattt taagaatatc tcaaatagca atgaacaggg aagcaagtct gttaccatta
     3721 tttgaggcag gagcgatata tcttatattt gtagctatac ttactaaggg atttgaatta
     3781 cttgaaaaaa aatattctta ttatagataa agttacaata ttataggagg aggtttttta
     3841 tatgttgaaa atcaaaaact taaataaatc atttaaaaaa aatagagtac ttaaagatat
     3901 ttcttttgag ttagaagaag gtcagattgg agttttactt ggtaagtctg gtgcaggaaa
     3961 gaccacaata ttaagatgta taaatggtct tgaagaattt gatagtggag agattataat
     4021 agataatgag gtaataaaaa ataagagaga tatggcaaaa atacgaggaa aaataggtat
     4081 ggtttttcaa aatttcaact tatttcctca tatgacagtc cttgaaaata taattgaatc
     4141 cccagttaat gtttttaaag ttcctagaaa agaggctgaa gagagggcta gagaactttt
     4201 aagattagtt gatttagaag ataaattaaa ttcttatcca tttgaattgt caggaggaca
     4261 gcaacagaga gttgctatag ctaggtcatg tgcattgatg ccaaaagtcc tttgttttga
     4321 tgaacctact tctgcacttg atattgatac tattcaaaga gtagtcaata taatgaatag
     4381 acttaaagac aaaggtatga caatattaat aattacacat gatgttgtct tctcaaataa
     4441 tgttgcagat aaaattataa gtataaaaga tggtatagta gaaaatgttc aaataaaaga
     4501 aaaaattgtt tagagtttta taaatataaa ctagggtaga attttataat ataaataaag
     4561 ggcaagtaaa atcaaatata ctatgccctt ttgttatctc aaaatttaat cttatatttt
     4621 atgtttaagt tacattataa tttataataa aaataaaagg actatttaaa tatataatgt
     4681 gaataaatgt ttaataattt gaaatatgat aattttttat gttgaaagct tataatgatt
     4741 atgatataaa ttggttatag tatacaattt atgggtataa caataaaaaa ttagaaagga
     4801 atttttataa aatgattaaa ttatatggat atacaaaatg ctctactgtt aaaaaagcta
     4861 aaaattggct taaggaaaat aatttagaat ttgaagatat agatatggtt caaaaccctc
     4921 ctagtaaaga ggagttaaaa tcaatttata agactagtgg atatgatata aagaaatttt
     4981 ttaatacaag tggtatgaaa tatagagaat tgggtcttaa agatattgta aaaactgaat
     5041 ctgatgataa acttttagaa atattggtaa gtgatggtat gcttattaaa agaccattac
     5101 ttttggatgg taaaaatgta ttattgggct ttaaagaaga tgtatggaaa agtactttgc
     5161 taaaagaaga ttaggaagag ataggtgtgt tgattaaaat tattaattaa tacacctata
     5221 aatttatgta ttaaatctaa tctttataaa tattaattag caaattcaaa tcaaaaaaat
     5281 tcatatcaac aaatatatta cttcttatta caaattatat catatgtttt atattaaaat
     5341 attataatat tacaacgaat tgttacaaaa ttacttatta ttaaccatga acatttgttt
     5401 tgtgctatca tatttatata agggaattgt cataaaaaat atcttgttca tacagtttta
     5461 tatagaaaaa agaaatgaat cttttcttta tataagtata ttttgtaaat tgcctctata
     5521 tttatagttt aaataatagt ggttttaaaa atctgacaac aaaaataaaa ctttcaaaaa
     5581 attaaatcta aaaagaatag gagataaata tgagtattga agatttatat gattttgaat
     5641 gtgttccttt gaacaatgag attgatattg atgttttatt tgaaaagatg atagaagatg
     5701 gaaaagaaaa agaatataca ccaattatag tcattgatga aaaagtaggg ctattaagaa
     5761 aaaatataga tatgattact aaagagtatg gttctcttga aaactataga gagtattgtt
     5821 taacaaaata taatgaaatt gatgtaaatc aattttttga ttttaggaag agtgagattt
     5881 cagaattatt aaaggagcta attgatttag aagatgattt ttatgattat aaacatttta
     5941 gaccaattat aaatatagat atatttcatg aatataacaa agtttacata gctaaaattc
     6001 caacaattaa accatatgaa gtatttgcat acatacctat tggaggattt aatgattgtc
     6061 ctagagatga agaacatata gctattgcaa aatattggta tgaaaagcat ggaatctttc
     6121 caatcgcaat tggatgtgat acagttcaat attctgtaaa aaatttaact aaagatggta
     6181 aaaaatttga tgacttatgt attgaattag tattttattg tgaggatatt attatacaag
     6241 ggtatgaaac cttaaaggct cttaaggatg tattaaaacg ctctacaata gtgctttttt
     6301 ggtgggattg atattctatc atttagatag tattaaattg ttagtcacca agaatccact
     6361 tactttagtt atggggagtg tgtcaaacta ggtttttata cacagtgtag catagtaata
     6421 tgtttaaatt acaaaggtta aaaaaatact ttaatatttt taatattata attaatagat
     6481 ttaaaggtaa ttataattta taaaataaat actttatatg ttataatcat taagaatgta
     6541 aaaaaataat atatagtttt atagttcata tttttccaga tatggaggta aattttgtga
     6601 aggaaaaaga aaaattagat aaattaaaaa aaatgttact tgaattaggc agtgttgtag
     6661 ttgcttattc tggtggagta gatagtaatt ttttgcttaa ggtcgcaaaa gatacattag
     6721 gtgaaaatgt tatagctgtg accattcatg caatgatgca ttcaagtagg gaaattgaag
     6781 aggctaaaca atatactcaa aattttggcg ttaaacatat catattaaat atagaaaact
     6841 ttgatttaaa agaatttaaa gaaaatggtg ttgatagatg ttatcattgt aaaaaatata
     6901 tattctctaa aataaaagag gtagcaaaag aacataatat aaagtacata gtagatggga
     6961 caaatatgga tgatttagga gactatagac ctgggcttaa ggcattgagt gaattaggag
     7021 tgattagtcc attaaaagat agtagtttaa aaaaagaaga aattaggtcg ctttcaaaaa
     7081 tattaggatt aaatactttt aataaaccat catttgcatg tcttgcaagt aggattcctt
     7141 atggagttga gataacagat gaaaatttaa gaatagtaga aaagagtgaa gaatatctat
     7201 tcaatttagg tttttctcaa tttagagtga gaatgcatgg agagatagct agaatagaag
     7261 ttgggcagga agaactaggt aaattttttg aaaataacaa ttttaataaa gttgatacta
     7321 aattaaaaat atttggcttt aaatatgtta cactagatat gtcaggatat aaaatgggaa
     7381 gtatgaattt aaatgtgtag attattttaa aaataaataa gttttatagt taatataagg
     7441 aaacaggagg ttttatgaaa aattatacat taatatcgcc atgttttttt ggaatggaaa
     7501 aaatgctggc tagagagatt actaatttag gatatgaaat aataaaaaca gaagatggaa
     7561 gaataacata taaaactgat gagtttggaa tagcaaagtc aaacatgtgg ttgagatgtg
     7621 ctgaaagagt acatcttaaa attgctgaat ttgaggcaaa aagctttgat gaattatttg
     7681 aaaatacaaa aagaataaac tggtctagat atatacctta tggagctcaa tttcctatat
     7741 caaaagcttc ctctataaaa tcaaaattat acagtacacc agatgtacaa gccatagtaa
     7801 aaaaggctat agtagaaagc ttaaagaaaa gttatttaga ggatggtttg cttaaagaag
     7861 ataaggagaa ataccctatt tttgtattta tacacaaaga taaagtaacc atttctatag
     7921 atacaacagg agatgctttg cataagagag gatatagaga aaaggcaaat aaagctccaa
     7981 taagagagac tttagctgct gggcttattt atttaactcc ctggaaagca ggtagagttt
     8041 tagtagaccc tatgtgtggt tctggtacta tattgattga agctgctatg attggtataa
     8101 atatggcacc tggcttaaat agagagttta tatcagaaaa gtggagaact cttgataaga
     8161 aaatatggtg ggatgtaaga aaagatgctt ttaataagat agataatgaa tctaaattta
     8221 agatttatgg atatgatata gatgaagaat ctatagatat agctagagaa aatgctgaaa
     8281 tagcaggtgt agatgaatat atagagttta atgtaggaga tgcaactcaa tttaaaagtg
     8341 aagatgagtt tggatttata atcactaatc ctccttacgg agaaagatta gaagataaag
     8401 acagtgttaa acagttgtat aaggagcttg gttatgcatt tagaaaatta aaaaattggt
     8461 cgtattattt gataacttct tatgaagact ttgaatatga gtttgggcaa aaagcagaca
     8521 aaaaaagaaa attgtataat ggtatgttaa aaactaactt tttccaatat ccgggtccta
     8581 agcctcctag aaataataaa taagttttac atgatttatt tgtaaaatat aaaattttat
     8641 taaaataagt aaaacattat gatgccttga aacgtctaat tattgtgagg agatttttgt
     8701 gaacaaattt aaagatttat aggattagga ggagttaaat gaaagtgtta aagcttatta
     8761 ctgtagtagc cctgatgatg ttatttgtta ctggatgtaa tataaaaact gaatctccag
     8821 aacaattagc gaagatacct gactatgatg atacaaaaaa agtattgtat gatggtattg
     8881 accagttact aaaaccagat tcatctatga tattgccttc taatacaaaa gaagtaggaa
     8941 aaataaataa ggtagattta aacagcgatg gaattgatga attagtagta tttgaacaaa
     9001 aagaagattt aagtaataat gtgagtcagg tagggtttgt aaccttgagt tacaatggag
     9061 aaaaatacgt acttggagac cattttttag aaaatggcga atcaatagaa tatgctaatt
     9121 tttatgattt ggactcagat ggatataagg aagttatctt attggttaaa tccaaagaca
     9181 aaacgaatat gcatatatat aaagtagtag ataatgaaat aacaaaaata tatgacttgg
     9241 atgcatcatg gcttcaaaat aaagaagatt ttaatgacat gaaagtaaaa attggatata
     9301 tagatggaga tgacaagtta gacatattga tgcttcattt gaataataag actaatgaaa
     9361 tgtttgcaag tgttgcaaat tttgatggga aaatgaaaat caaagattct gttaagtttg
     9421 aaaatgtaaa aaacttaagt gaattatata caacattagg taatgttgct tcatctgttg
     9481 gaaattcttc tgcagctata aaaggtattg tacttgatat tcctatattg aaagataata
     9541 actatattac gcagatactt tatatgaaag atgggaaaat taacaaagct tttagtgatt
     9601 atgataaaac tattactaaa tcttattata tacctgtaga tgatattgac aaagataaga
     9661 ttatagaaat acctatagtt gcaggcagta caggtaataa taaaaatact tatagttcta
     9721 aatcatctgc aactataagt tggtatagat ggaatggaaa agaaggtgct gactcaagtt
     9781 taatatttac aagtcagata tattataatt ataaatataa ttttaaatta tttattccaa
     9841 ataatttatt tgataaaata cttgttgaac aggaatttgt tggagaaaaa gcagtattta
     9901 aattttacta ttttgactat tcagatcgta agaatttatt taatatagta gtagagagta
     9961 aaaacaaact tgaagataga aaaaatacag gtactcaaaa ctctattgta cttcaagaga
    10021 gcgatgaata tactttctta ctagttgtaa acaatgcaaa tgaaatggat aagctagata
    10081 tgactataga cgcattaaaa gaatatttct cattaatata tggttaatat tatactcaat
    10141 tggaggtttt attttatgaa ggaaaagata cttatactag aagatgaaat tggtattaga
    10201 agttttgtta gtataaactt aaaaagagaa ggctatgaaa tagttgaggc aggtactgga
    10261 agagaagcta tagaaaaaat gacaacagaa aatgatatta caatagctct tttagatgtg
    10321 atgcttccag atataagtgg tatagaagta tgtaaattta taagggagaa ttttgaccaa
    10381 gtaggtataa taatgcttac tgctaaagct caagaggatg ataaaataga aggatttatt
    10441 tcaggagcag atgattacat cataaaacca tttagtataa aagagctttt agtcagggtt
    10501 tctgctcttc ttagaagagt agcaaaggat gattcaagtg ttaagtcgag tgaaatagtt
    10561 tctccaccat ttatacttga tatagacaag agaaaattat ttaaaaatgg aaaggaaatt
    10621 gagcttacac caactgaatt ttcaatagtg aaatatctaa tatcaaatgc taagcaatcg
    10681 ttaagtagag accagatatt agacgaagta tggggaacta actatttata tgattttaaa
    10741 atagtagatg taaatataag aaggataaga aataaaatag aagatgaccc atcaaagcca
    10801 aaatatatac aaactatttg gggttatgga tactgtttta gaaaggaaga ataatagtgt
    10861 tacattttga aggtctgaga aaaaaagtaa taaaaaacta ttttataata attattataa
    10921 tggttactct gtttgaagga ttgttcatgt tttacataca aaactactat tatgattctg
    10981 tcaaacaact acttgaatct gaaataaaat atgctgatga atataatgct attacaatgg
    11041 aaactacaag ttttgagaaa aaagtaaaaa atatatttga taaacaacca ttaactaaaa
    11101 attcagaatt tggaatttca ataatagata aagataaaaa tattatatta gaccaatatg
    11161 gttttaaaag taaagaaaaa gcaaactatg aagatgttaa caatgcatta aaagatataa
    11221 aaactaaaaa tttaacacct tatacttata gaataccaga tacaggggag catgttatga
    11281 gtatctcctt accacttaag gtaaataata taatagaagg tgttgttaga tatacagtat
    11341 cattagatgc tattgataat gcaatattaa agcaagctac atggcttata ttagcaggaa
    11401 tatttatact tattatagct atactaataa gtcttaaatt tgctgagact cttataaaac
    11461 cattacgaga gctaaagaaa tttgcaaatg aattggctgt aggaaattat aatataaaat
    11521 tagaaaagat gaagattgta gatgatgaga ttggtgattt agcacagaca tttgaacaca
    11581 tggcacatga gattgacaaa agtgaaaaat taaaagagga atttatatca tctgtatctc
    11641 atgaactaag gactcctctt acatctataa aggggtggag tgaaacctta ggttatgaaa
    11701 gtataacaag agaagaacta gacttaggtt taggcattat acaagatgaa acagaaagac
    11761 ttataaaact agttgaagaa ttattagact tttcaaggct ttcttcagac aggataaaac
    11821 ttcatgttga tatagttgat gttgaaggtt taattgtagg tgttgtaaat caacttaaag
    11881 ttaaagcagc tgaaaaagat atatcacttt tatttgaatt tgaaaatgaa tttatagaga
    11941 acattcaagg agataaaaat agattaagac aggttctcat aaatttaata caaaattcat
    12001 ttaaatttac gagtcaaggt ggttacataa aagttgtagc ttctcaagat gaagagataa
    12061 caaccatatc agtagaggat aatggttcag gtatagaaaa gcaaaattta aataaagtgt
    12121 tagataaatt tttccaagaa gattataata aggctggtag tggattagga ttagcaatta
    12181 gtaatgaaat tgtaaaactt catggtggaa gaatgaaaat agaaagtgaa aagaatgttg
    12241 gaacaaaaat aacttttaat ataaaaaata aatttgctaa acaagcataa attcttagaa
    12301 agaggattaa gatgagaaac ataaaaatga tagtagcata cgatggttca agatataaag
    12361 gatatcaaaa attaggtgac aataatatga ctattcaaga aaaacttgaa aatgttttaa
    12421 gtaaaatgac taatgaaaca gtggagataa tagggtctgg aagaactgat atgggagctc
    12481 atgcaagagg acaagtggta aattttagaa ctaattgtat ggattctttg gataaaattc
    12541 aaaaatattt atatgaatat ttaccagaag atatagttgt aaaaactgtt gaagaagttg
    12601 atgaaagatt tcattcaaga tacaatgtaa aatcaaagac ttatatgtat aaaattgaca
    12661 ataataagta tcacaatcct tttataagaa aatatgctac tcatgtaagt aaaaaattag
    12721 atttagatag aatgagaaaa gcaagtgagt atttagtagg agaacatgat tttactagtt
    12781 ttgcttcttc taaatctaag aaaaaatcaa atgtaagaga aatttattct ataaatataa
    12841 aagaagatga taatgttata gaaatatatg tagaaggaaa tggatttttg tacaacatgg
    12901 taaggataat agtaggtgct ttgatagatg ttggtctaaa aagaagagct ccacaagata
    12961 ttaagtatat gcttgaatca aaagatagat gtcaatcatc agatactgca ccagctaaag
    13021 gactatgtct ttggaaagta acatattagt caattatata aaactctctt taaaataaaa
    13081 ataaaataaa ttatatagtt gacataaatg gaaaaataaa ctattatata ttttataaga
    13141 gagatataaa actttatatt taaatcctgt gagaaagaga gtaacttcta tgtgttttat
    13201 agagagctga ggatggtgga agctcagcaa ataagtatta gtgaaaagaa ctttggagga
    13261 tactaattga atttagtatg ttagtaggta atctcgcctt aagagaaaga gtggataagt
    13321 ttatcttatc aattagagtg gtaacgcgga tatatttcgt ctcttggttt ttccaagagg
    13381 cgttttttaa tatatttaat tattagtgtt tatctggtat gttgaacatt tactaattga
    13441 ttagctaagt ttatcaataa gagtggtacc gcggatattt cgcctcttag tattttaaaa
    13501 tactaagggg tttttttagt attaaaatga ttttatgtga gtctaaattc tcagagtcat
    13561 tcaatattaa gaatttctat aaaataaaaa ttataattta agattgggag gaattaaaaa
    13621 tgaaggaaaa agtagtatta gcatattcag gaggacttga cacatcaatc ataatacctt
    13681 ggttaaagga aaattatgaa gatatagatg ttatagctgt ttgtggaaat gtaggtcagg
    13741 aagataaaat ggaagatgta tatgaaaaag ctttacaaag tggagcatca aaggcatatg
    13801 tggatgatat aagtgaagaa tttgtaactg aaactatatt taaagccgta aaagcagagg
    13861 ctaaatatga aggaaaatac ttattaggaa cttctttagc aagacctata atagctaaaa
    13921 aattagttga agttgctcat aaagaaggtg caaaatatat atgccatgga tgtacaggaa
    13981 aaggtaatga ccaagttaga tttgaagcta caattgcagc tcttgacccg actataaaag
    14041 ttattgcacc ttggagaatt tgggatataa aatcaagaga agatgctata gactatgctg
    14101 aaaaacataa tataaaggta acagcaacta aagctaaaat atattcagta gatgctaacc
    14161 tttggcatgt ttcaacagaa ggtggagata tagagcacct agaaaatgaa cataaaaaag
    14221 atgtttataa acaatgtgta gacccagaag atgcatgtga tgtagctgaa tatgtagaag
    14281 tttactttga aaaaggtgta cctaaaaaag taaatggcga agaattatct ccagttgcac
    14341 tgattcataa gttaaatgag ttgggttgta aacatggaat tggtgttata gatatagttg
    14401 agaatagact tgttggtatg aaatcaagag gtatatatga gactccagga ggaacaatcc
    14461 tttatgaagc acataatatt ttagaaagtg ctactttaga caaagataca ttacatttca
    14521 aacaaatggt atcttataaa tacggagaac ttatttacaa tggactatgg tattgtaaat
    14581 taagagaatc tatagatgca tttatggaac aaactcaaga taatgttaca ggaacagtaa
    14641 aagttaaact ttacaaagga aatataaaac ctgctggaat atttactgaa aatgctcttt
    14701 atgatgaagg aatatcttct tttggaaata gtgaacttta tgaccacaaa gatgcagaag
    14761 gatttattaa tttattcact ttaccattaa aaatcagagc tatgaaagct ggaaaataat
    14821 aaaataaatt atttaagagt gtataaaaac tatttttagg tttttatatg ctcttttttt
    14881 atttgaattt attaaattat acagtaaata gtataaaaaa atatattata gttccaaatg
    14941 acttaataat gtgaaaatat aagacctaaa atataaattt tataaataca atagttattg
    15001 actctctcat tgtaagaggg tttatactga atctaatgaa aatttatagt gaggagatag
    15061 attatatgag aaaaataatt gaaattaaac atcattcaca tgattatgag tgtatgtgga
    15121 atggtataga agatttatat ataaataaaa ccggtgaatg ccttccaaac gattttttct
    15181 ttttactgtc aggttttggt tcattttgtt atatgaaaac aaataaagct gatttgaaaa
    15241 gaatggtagc tttgggagat ggaaggacaa aacagatgta taaattttta gcaccaattg
    15301 ttggatttga atacaaacat catgagttta aaaagtatga gcaagcatta aagaaagcaa
    15361 aatctgaaat tgatggtgga tatccagtta ttttaggagc tttagatatg tattatctac
    15421 catattataa gaagctatat cataaagaac acattccttt tcattatata ttaatggtag
    15481 gatatgatga tgaaagaata tatctgtatg attgtggtag aacagaatta ttacatcttt
    15541 cttatgataa attacgtgaa agcatgaatt gcaattcccc tggattaagc aaagaaaata
    15601 ctatttgcac aataagaatg aatacttcaa agaataaata taacattgct agagaagcta
    15661 ttgctataaa gcgtgatatg tttttaaatc catctaaagg atttttggga tataaaggtt
    15721 ttgaaaagtt tattaaagag ttgccacagt ggaacactga attggataaa gatgattatg
    15781 ataagatttt gaccaatatg gttatgtttt ttggaacagt accaacaatt ccaaatgcaa
    15841 tcaaaggaat taaagaacca gatactgttc aatttaaagg tggatttgat aaaatgagta
    15901 gaatgctcaa cagtattggg gaggaataca aaaacgactc ttttatacaa gtagctgata
    15961 tttttgataa aactgctatt ataattgaga aaatatccaa tattataata gattatttaa
    16021 ctcaaacatg tgatgataca gaacaacttc cgttattgtt ctctgaggtc ttagagcata
    16081 tgaaaacagg atatttaatc ttggatgtat aaaaaatata ttgttgaccc taacattacg
    16141 taatagtgta atatgaaaat atagcttgaa tatattagta ggtattgatg gctgtaaaat
    16201 taaaatttga ggtgtggata tgagaacagt gaaacaagtt tctgatttaa ctggaataag
    16261 tgtgagggca ttacattatt atgatgagat aggtctttta aaaccaaata aaattacaga
    16321 tgcaggatat agactttatg atgatgaatc tattaaaact cttcaacaaa ttttattttt
    16381 taaggagatt gatattcctt taagagaggt taaggaaata atgtcaagcc aatattttga
    16441 taaggttgaa gctctaaaaa atcaaaaaaa attacttatt ttaaaacgaa agagactgga
    16501 tgaattgata gagcttataa atcaaactct aagaggagaa ggaaatattg attttaaaga
    16561 gtttgatatg agcgagtatt ttaatgtttt agaagaattt aaaagagaac ataggaataa
    16621 gataattaaa atttatggta gtgtagaaaa atacaatgaa tatatagaaa gagttaagtc
    16681 taatgaagag aaaattgcta aaatggctat aaaacaatat ggaactattg agaagtttgc
    16741 ccaagctata aaaacaaatt ttagcagtga tatattgaat ttaggagaaa aatttgatag
    16801 atataaaaat gattgtttaa aagaaaaaca tccaaaatta aaagaattat atagaaagct
    16861 tgtagaagat ttaagtaaga atccttcttc aacagacctt caagaaatag caaaagagat
    16921 aacagatata tctaaaaaag attatgaaat tttctctatg tatactggtg atgacaactg
    16981 gtattatatg attcaaaatt atctagtaaa tcctatgtgg atagaagaag tagataaaaa
    17041 gtatggaagt ggagcaggca agtttattgg acaagtacta aagacttatc taagagatag
    17101 aaaaccaaag ataaatacat tgtatgaaaa acttgtagaa gatttgagta gagattgttc
    17161 ttcaagggaa gttcaaagca ttgttgaaga aatagacaat gaaatgaaaa gaagtaatga
    17221 attttataaa atagacaatg gtgaaagata ctttgattat atgtcagagc tttatttaca
    17281 agattctaac tatataaaag taactgataa gaattatggt gatggtgcat ctaagtttat
    17341 tggagaagct tttaagattt attttgataa taataattgt tgaaaatttg gaagtaaaaa
    17401 atatgtaagt tttataaaag cacaaaaata aggatgtaga ttagctccat ctatatcctt
    17461 atttaaagtt attaaaatat atagtttaca tcaaacttaa cactttcaat aatatttccc
    17521 aaatatgttt ttatactttc aacttcttct aaagatttta atttattttc agtataaatt
    17581 gctttgtcca gaatattaaa ccttaatcct atttcatcaa agtactcatg atttaaaact
    17641 ttgtaccaat ggtttttttc tttattccaa ctcgtagata ttgaatcagc ttctttttga
    17701 gctttttccc aatcttcatt ttctatagat ttttctaaaa cagatatatt gtctttatat
    17761 ccttctgtaa aatcatatag tttattgtta acgtaaaatc caaataatac aaataagata
    17821 gtccatagta taacaaatgt tgtagatttc aatattaatc acccttttta ttttgaataa
    17881 atattttgtc attttcatct aaaacacaaa taagaacatc tttaaaagtt tctatgtgat
    17941 tagattttaa aatacccatt aaccagttag tatctttttg agctatgtct agatttttat
    18001 ttattattct accatccagt ataagtggga taggtaaatg attaaaagct cttggaggag
    18061 tactattgta gcttgatgct ggtacaacac ttagattacc atcagtctcc aaaatagcat
    18121 attgtacatc ttttaggttg aagtatcctt gaatcctaag ttgttctaat aattcatcta
    18181 tactaattct ttctttttta agctctttat atacaatttt tcctttatct attaatacag
    18241 aaggtttacc tgataaaaat gaacttaatt ttctgctttt taatgataag aatgaaataa
    18301 gagtctgcat gattacaaga ccagatattg ctgcaacacc atttatgatt ggtatattat
    18361 tattttccat tgggacagat gcaacttctg caattaatag tgttataact aaatcaaaac
    18421 agttcatttc agctatttca ccttttccca tgactctaag tgcaattagc actgttatgt
    18481 ataatataat acttcttatt aatactactg tcatatctat caattactcc tttaaaaaat
    18541 atttacactt agttagtata tcctatataa aaaatttaat tcaaagtata aaaaacctta
    18601 aataattgga ttcaactatt taaggttttt ttgataattt taatattaaa ttttttatgg
    18661 attttctgtt acttttattt attttaataa cagattcaac aaaactcttt ttatctccta
    18721 attttaagat aaaatcagga tattcttcaa attcattgag ttttattaat ttgaaagaag
    18781 aagatagatt tttaaagtta atgattttag agttattcac taatacactt ctttttttaa
    18841 aataaatttc ttttttactt atatttagta tagttaatat ttgtttaaga tatattatta
    18901 tatcttctgg agttctatca aatttgagtt caaaattttc atcttcaaag tagggaatat
    18961 aatataaagg tgttttgaga gcaggtaatt tattatataa ttcttcaaga atatcgatat
    19021 ttttagggga gttaaagaaa aagcatttac atacgttcat taaatccaca gcatctgaaa
    19081 gtgagttatg tttaatatct ccttctacag aaaaaatttt tttcatattc agtaaagata
    19141 tttgcttaga taagattcta ttattgtatg taatatgttg agatataaaa ggttgaatgt
    19201 caatcatcat attaaataac tctaagcatt tacctgtata tttatatact ctaaatgaag
    19261 ttagaaggcc agttatatca aaatcacccc aattatatat tgtaacatca tcaaatttac
    19321 aaaaccattt ataaaaatca tccataacat ataaaagatt aggagcatta ttgatatcta
    19381 gttggttcaa tttggttaaa tttttacatt tatttgaaag tattttattg tattttggct
    19441 taactaaaga gtaataatta tctattgtat taaattcgtt atcaactaaa actccaccaa
    19501 tagaaattaa ttccgcacca ttatattctt ttggtttatt tttattatca tctagtatat
    19561 taaattcaaa gtctataaat aacttgtatt tcataaatct aaagcacatc ctcaggtaaa
    19621 ttatttattg agcctaagca tcataagaat caatagatat aatgactcta aacatcaaag
    19681 gttcattaca acttttattt atttcataat ttaattcaaa taaatctttt aagatataat
    19741 ttataagtat tctttcccaa cccattttta aattaacttt agagtctatt aatatatttt
    19801 ctatcttttt aaatatttct atatttgctg gtattatact gagctcaata ttacttttaa
    19861 acgggttaga ctgtaaatct gttataagta tattttttaa ttcctctgta agttcagaaa
    19921 ttaaactatc acctatgtat ttttttatga tttcctctct aatttctttt aaatttagca
    19981 atattagtac ctgctactta catagtagct tttcctttcc ttttaatact attattcatt
    20041 tttgaatctt atttagatat attttaagat taaaagtctt tagctatata attttttacc
    20101 catttttaac ttatattaac atattacagg cttatatctc caccctgctt acattgagga
    20161 tggagtatat tgcctatttt gataaaaatg ataggttgtt atttgcctat tcctttttct
    20221 gataattttt ctaacatatc tttggtcatt ttatctaaat cataactaaa cttaaagttc
    20281 cattctttta ctgcactact actgtctaga gagttaggcc aagaatcagc tatactttgt
    20341 cttacagggt ctacatcata ttctatcaca aaatcaggaa tatatttttt tatagaatca
    20401 gctatttctt caggagaaaa gctcatagca gtaatattaa aagcatttct atggatgagt
    20461 ttatccgctg gagcttggat taaatccact attgattgaa gtgcatcagg catatacatc
    20521 atatccattt ttgtaccttc tgctatgtaa gatttatatc tcttattttt taatgcctca
    20581 taatatatat caactgcata atctgtagtt cctccaccag gaggcgtaac ataagaaata
    20641 agacctggaa atctaacacc tctagtgtct actccaaatt ttgagtgata ataatcacat
    20701 agtaattctc cagaaacttt agtcacacca tatatagtat taggtctttg taatgtatct
    20761 tgaggagtca tattttttgg agaattttca ccaaaagcag caattgaact aggtgtaaaa
    20821 aatttacaat ccaattcttt ggctatttca aggccattta ttaatccatt catatttaag
    20881 ttccaagctt ctaggggttt actttcagca actgcagaaa gtaaagatgc tagatgaatt
    20941 atagtatcta catcatattt ttttgcaatt tcaaaaaaac gattcttatc tgtaacatct
    21001 aatatctcaa atataccaga ttcacatact ggattacctt cttttactct ccttgaacta
    21061 gcgattacat tttgttctcc atactcattt ctaagcttta ttgttaattc tgaacctatt
    21121 tgtcctaatg cacctgttat aagtattttt ttcaatttta caacctccta agggtttaat
    21181 ttatgtagta ctacttattt ttattttagc aaatcttttg tttaaataca aagaattaaa
    21241 gataataata tacgacttaa ttgaatgaag tgcagtaaat tcctaaaaat ttaaagttga
    21301 gatataatgg tctattgtat aacaataaaa gactagatta aattattata tagattgtgt
    21361 gactaagtca cagaaagtat agttaattta atatataata aaagcatatc aagtaaagct
    21421 ttaaattaaa gtaactttat ataaaaagta atataaattg ataaaattat aaatttattt
    21481 atagtgaata taggttggat tttatagata caaaaatagt atatatgata tgtagaccat
    21541 tagcatgttt aaagtagcaa aacatataaa ataaaatttg aaaggaagta taaaaatgac
    21601 aagaccatca atatatcata gccaaggata cacttgtgca gaggcattaa taaagtctta
    21661 taatgaggaa cacaacacag atataccaat ctcaatagga agtggtatgg gggttggaat
    21721 gaatgttgga agtgtttgtg gagctgtaaa tgctgctgtt gttataatag ggtatttaaa
    21781 tgggcgaaat agtaatttag atgaaaatat agcaaggaag tattcaagag agctattgaa
    21841 taaagtaaga aataaataca gctcagaaat atgtgtatct cttaaaaaaa ataaagtaac
    21901 ttgtgaagaa ataataaatt tcacatatga tgctctaaat gatatgctaa aaaatcaaaa
    21961 ataattctaa gaaacaagta ttttacattc gatagaatac ttgttttttt atgatatttt
    22021 taataggtat tagtttatta taatttttaa atcaatttta ttatatttta attgaaataa
    22081 tctactttga aaattactaa ctgacaaaag aatatgatta tagtatagaa aaaatgtaaa
    22141 ttattt
//
LOCUS       DAMJYN010000064        21934 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.065, whole genome shotgun sequence.
ACCESSION   DAMJYN010000064 DAMJYN010000000
VERSION     DAMJYN010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21934)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21934)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21934
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.065"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(55..1326)
                     /gene="serS"
                     /locus_tag="PC466_002621"
     CDS             complement(55..1326)
                     /gene="serS"
                     /locus_tag="PC466_002621"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HDF2769988.1"
                     /translation="MLDIKRIRENLDCIKKAMERRGEKDFNLDEVVKLDDERRKILQE
                     VEVMKHKLNTASKNIPNLIKEGKDVENEKIKLKELSDKIKVIDQNLKEVEDKMEYLLM
                     RIPNVPHPEVPQGETDEDNVEVRTWGKTTTFDFESKAHWEIGTELGILDFETASKITG
                     SRFTLYKGLGARLERALLNFYLDTNTKVNGYTEVIPPFMANRNSFLGTGQLPKFEEDM
                     FKIEGLDYFMIPTSEVPLTNIHANEILKFEQLPINYTAYTPCFRSEAGSAGRDTRGLV
                     RQHQFNKVEMVKIVAPEESYNELEKLTNNAETMLQLLNLPYRVVKICTGDLGFTASFK
                     YDVEVWMPSYNRYVEISSCSNCEDFQARRAGIRFKRDKDSKAEYVHTLNGSGLAIGRS
                     VAAILENYQQEDGSVVVPEVLRPYMGVSVIK"
     gene            complement(2143..3747)
                     /locus_tag="PC466_002622"
     CDS             complement(2143..3747)
                     /locus_tag="PC466_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2769989.1"
                     /translation="MKEKIYYNGNIITMEDSICGDAILIKDKIIKKIGTKEEVFALKN
                     KDTEIIDLQGKTLMPSFIDSHSHLIAFATTLKLVPLEDATSFKDIVKKIQDFKESNNI
                     KKGDWIIGFSYDNNFLEENKHPDKSVLDSASSENPILISHASGHMGAANTLGLKQLGV
                     TNETRDPEGGHIGRVEGSEEPNGYLEENAFFNVASKIKQPSSNEIFNSIEKAQNIYLS
                     YGITTAQEGLMEENQFNILKAMANQNKLKMDVVGYVNLKKSKSVLDNNREFIKKYINR
                     FKVGGYKIFLDGSPQGKTAWLSRPYENSDDGYCGYPIYKDEEVEKFIDISLKEKMQLL
                     THCNGDAAADQLIDAFEKVLNLKEQSSENNIRPVMIHAQTVRADQIDDMKVINMIPSY
                     FVAHTYYWGDIHIKNLGEDRAFKISPLKTTIEKGLIYTLHQDTPVIAPNMLETVWCAV
                     NRITKKGIQIGENEKISPLDALKGVTINAAYQYFEEDKKGSIKEGKLANLIILDENPL
                     TIDPMKIKDIKVLQTIREGEVLYSLK"
     gene            4133..5059
                     /locus_tag="PC466_002623"
     CDS             4133..5059
                     /locus_tag="PC466_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="HDF2769990.1"
                     /translation="MSKENKNVRIAVVQASPVIMDLEKTVEKALGLIKEAGRKGANIV
                     VFPEAFIPAYPRGLSFGFVVGSRTMEGREDWKRYYDNSVPVPSATTDLLGKAAQEAGV
                     YLSMGITERDGNDINCTLYCTNLFFSPEGKLIGKHRKLKPTGTERCIWGEGDGSTLTV
                     VDTPYGKMGSLICWENYMPLARTVLYAKGVKLYIAPTADSREEWQATMKHIALEGRCF
                     VIGCNQYVEKNMYPTDLNYYKELDAEPEIMCPGGSCIVDPFGKYVAGPIFNKEEMLIA
                     DLDLEKIVLSRLDFDSEGHYSRPDVFELIVHE"
     gene            complement(5179..6177)
                     /locus_tag="PC466_002624"
     CDS             complement(5179..6177)
                     /locus_tag="PC466_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhdH/YhfP family quinone oxidoreductase"
                     /protein_id="HDF2769991.1"
                     /translation="MNKKFKSLYITEEEGNFRRNIVEREVDTLPEGEVLIKVKYSSLN
                     YKDALSANGNKGVTRKYPHTPGIDASGIVESSSCDDFKIGEEVLVTGYDLGMNTSGGF
                     SEYIRVPSSWVVKLPKNLSLKEAMDYGTAGFTAALSVYKFIDSVDKNMGDVLVTGGTG
                     GVAVIATKILIKLGYSVVVSTGKLEEQKEVLLNLGVKDVIHRSEVDDNSGRPLLRPRW
                     AGVIDTVGGNTLATAIKTTNYCGAVTTCGNAGGVDFTSSVYPFILKGITLYGIDSVDC
                     PMNLRLKIWDLLSNEWKLDDLDDMVNVVSLEELNDSIDSIMTGKHVGRTVVDLEKI"
     gene            6281..6718
                     /locus_tag="PC466_002625"
     CDS             6281..6718
                     /locus_tag="PC466_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF2769992.1"
                     /translation="MEDKYIVHFISKTKASMIKFIENKLSKNGLGELIPTHGNILTAL
                     YENNGILTMKEIAAKIGKDKSTVTVLVNKLINLGYLERQKCTNDKRITYIKLTKKALL
                     IEDTFNSISTQVKETAYHNITENEKQEFLRILKKINDNFKNAD"
     gene            6804..7391
                     /locus_tag="PC466_002626"
     CDS             6804..7391
                     /locus_tag="PC466_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rubrerythrin family protein"
                     /protein_id="HDF2769993.1"
                     /translation="MNLKDSKTKENLLRAFAGESQARNRYNISASVAKKEGLYIIESL
                     FNYTADQEKSHAKQFFSKLKEFAGENISISGAYPVDLYDKTAQHLKAAQHNELQEWDD
                     VYKNFGKTAREEGFESIAKLFENIAEIEKVHGDRFGRYATDLEEGTLFRRNEDIQWIC
                     THCGHIHIGKEAPKACPVCLHPQGYFLDFKNSLFE"
     gene            complement(7691..8311)
                     /locus_tag="PC466_002627"
     CDS             complement(7691..8311)
                     /locus_tag="PC466_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhbD family protein"
                     /protein_id="HDF2769994.1"
                     /translation="MEELISKKDLLSKTNISYGQLYRWKRKNIIPEEWFIKKSAFTGQ
                     ETFFPRDKILERIELILSMKEETSLDDIANMFMKKDINKEFDIDFILSKEVICNYTKE
                     IFQNLYKKEQSIGKKELLILSIIEKFLVKSIITFEELKLIVNIIEENFTSIYNESGKI
                     YLFRKFGVPFVVGCLDYKKVKFEKDVVKIIEIDLTKEINDISIKLS"
     gene            complement(8319..9086)
                     /locus_tag="PC466_002628"
     CDS             complement(8319..9086)
                     /locus_tag="PC466_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polymer-forming cytoskeletal protein"
                     /protein_id="HDF2769995.1"
                     /translation="MEKGSIKILGEGFISSGEYENIKIVGSSKSKGNVKSNEVKVLGD
                     AKFEGDINIKNFVVNGKTIIRGNLKAERVRVNGQLNIEGDAEIDDLVITAQQKVDGKL
                     KCNNVTIRGQLSVNENMYAQDIKIYGEMRNKSNIECEDIKVYGVIKCDGLLNGENIYV
                     YSGGGSYCKEIGATNIKIGRSKDAFSLIKIINIFSGKFKCNLIEGDTIELEDASIKDI
                     RGKSISLVDNCDVGNIEYSDNLSVSDNSTVKNSIKVG"
     gene            complement(9127..9948)
                     /locus_tag="PC466_002629"
     CDS             complement(9127..9948)
                     /locus_tag="PC466_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2769996.1"
                     /translation="MNEELSSLRFDGVGKCKGGIFDNVNISGTGKIEGSVKCSKFDSS
                     GSAKVFGTTECNEFFTSGLSKVEGNILASKVEISGLLRCTGNINSVEIDTSGIINVEG
                     SIKSDIIHGEGYLKANENIDCENINLSGILECNGFLNCEEVNISLNGTSNFNEVGASS
                     INIKKGHGDYCKKFRMLEKKHINFEKVSSNLISLGLLSIRKYTESKLFANIIEADEIS
                     LENSEVKVVRGKNIKIGKGCYVESLEYSESIEIDEDSIVGEIKNISEKIKLKKDK"
     gene            complement(10305..12215)
                     /gene="phnW"
                     /locus_tag="PC466_002630"
     CDS             complement(10305..12215)
                     /gene="phnW"
                     /locus_tag="PC466_002630"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HDF2769997.1"
                     /translation="MKKIYGEKIKAVVFDWAGTTVDYGCFAPLNVFIEIFKRRGIDVT
                     MEEARKPMGKLKIDHIREMCEMDRIKNLWSDKFGKVPTEDDVNELYAEFEPMLFETLE
                     EYTTPIPHVVETIEKLRKNGLKIGSTTGYTREMMNIVEPNAAKKGYSPDFLVTPSEVS
                     QGRPYPWMCYKNAEALGVSPMSSMVKVGDTISDVKEGVNAGMWSVAVIKGSSELGLTQ
                     EEVENMDKEELKAKMSIVSKKFKEAGAHFVIETMAELEDILIKIENETIKSDFVPEND
                     YILLTPGPLSTTKSVRASMLKDWCTWDVEYNNLVQDVRRRLVSLATQNTDKYTSVLMQ
                     GSGTFSVEAIIGSTISKDGKLLVIANGAYGKRMKDICNYLNIEFVDCTFKDIEAVDLN
                     VVENLLKENKDITHISMVHCETTTGRLNPIQEVGKLAKEYNKIYIVDAMSSFGGIEID
                     VEDFNIDFLVSSSNKCIQGVPGFGFIIANKEKLSKCKGIAKSLSLDVYAQWETMEKNN
                     GKWRFTSPTHVVRAFYQALLELEEEGSVEKRYARYKENQFTIASRLKSLGFDTLVNDN
                     AQSPVITTFLYPKNAKFEFMEFYTYLKDNGFVIYPGKLTDIDTFRIGSIGEVYPTDME
                     RLADVIEKFINR"
     gene            complement(12494..13279)
                     /locus_tag="PC466_002631"
     CDS             complement(12494..13279)
                     /locus_tag="PC466_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HDF2769998.1"
                     /translation="MSLNSIDRKKEILKLLDSKGKVNTKELVKRLEVSSETIRRYLEE
                     LENENKLKKVYGGAIKINYGVIEPEHIKRNNTNLDKKQSIAKYAAKFVNDNESIIIDE
                     GTTNLQIVDYIISVNNLKIITNSYPVLSKLISYENQGLFDGEVIFIGGKVNLKHQRTA
                     CPMSIDTMKNLYVDKAFISSEGILDSFGISSIDQNKALLSKEYIKNSKESFVLCDSSK
                     IGIASMYKIADLEELDFVICDVEPPNEWKDKLNEINITWIEAK"
     gene            complement(13496..13726)
                     /gene="dltC"
                     /locus_tag="PC466_002632"
     CDS             complement(13496..13726)
                     /gene="dltC"
                     /locus_tag="PC466_002632"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HDF2769999.1"
                     /translation="MQETVIEIFEDVLGTDEIREDLDLNLFETELLDSLAIIEVLLEI
                     ENRLGIELQPTDLERKDMSTVNNLVKFLETRK"
     gene            complement(13745..14893)
                     /gene="dltB"
                     /locus_tag="PC466_002633"
     CDS             complement(13745..14893)
                     /gene="dltB"
                     /locus_tag="PC466_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HDF2770000.1"
                     /translation="MIFSQYGDYFYLYILLLTSIPAVILGLMGKNIKYYGMLASLFMI
                     FLIVGIDVQLKYLVIFIILEVIIVKGYEYVRRKTKNKYIYWGFLFASMLPIIINKISP
                     VTSFGIIGFIGISYLNFRTIQMVIEIYDGAIKEVKISKMLYFMLFFPTLSSGPIDRSR
                     RFEQDLEKHISRKEYIEEYLLPGIKNIVMGVGYKFVIAFLINTYWVSRIPKDMSFINI
                     LSYMYAYSLYLFFDFAGYSLFAIGTGYIFGIQVPINFDKPFISKDMKEFWTRWHISLS
                     RWFGDYIFSRFVMSSMRKKRFKKRTTAAHVAQMITMITMGFWHGLTWYYVAYGVYQGL
                     ALVLTDIYQRKSKFYKKHKKDKWFERVQIFITFHIVCFGLLIFSGYLA"
     gene            complement(14893..16407)
                     /locus_tag="PC466_002634"
     CDS             complement(14893..16407)
                     /locus_tag="PC466_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase"
                     /protein_id="HDF2770001.1"
                     /translation="MKIIEGIKKYSNTDRTALMCNGDKLSYKDLNEYSDAISVFLKDV
                     YKEEDTPIVIYGNKENMIMACMIGALKSGRAYVPLDISFPIDRVFEVTKEIKPKVIFN
                     FSDERNFGDINVIDMDKLNDIINEYQGKSLDKENWVKDDENAYILFTSGSTGKPKGVQ
                     ISSNNLDSFSDWISPYLNIDGSEKVIMNQPAYSFDLSVTTIYPGLIHGATLFSISKDV
                     LADYKELFRQFSISDIAVWVSTPSFAGVCITEKEFNSKMLPNLESMIFIGEALSKNLT
                     KELMSRFPNTRIINGYGPTEATVGVSVNDMTQKAIDDEKSLPVGYPMSNCKIKILDED
                     GNELKENEKGEIIIIGPSVSKGYFNNKEKTDEVFFYDEIDGVKWRAYKTGDMGYLLDG
                     NIYYCGRKDFQIKLNGFRIEIEDIENNLRKVHNVKNAVVLPVYKDEKIAYLKGIVELN
                     EKNDLSNIKNGMIIKKELGKYIPSYMIPRNISIISEFPTNINGKIDRKKLMEEI"
     gene            complement(16528..17718)
                     /gene="dltD"
                     /locus_tag="PC466_002635"
     CDS             complement(16528..17718)
                     /gene="dltD"
                     /locus_tag="PC466_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HDF2770002.1"
                     /translation="MRKLIYFITPFIIGVVFLFGLDKFLDSKTDELLREKNLLPIMDD
                     TLSDIKDKGVTANNHFLREKDIMILGSSELSNSTKQHPKYYFNTNRSKNKVFAIGRAY
                     TQTLQDAAILGSMNPNIDNKKVVLLISMQWFMEKDGVTSHHYQSRFSPIQFYRFLDNP
                     KISKQNKIEYAKKSSKLLWGSDEYKAEALYAKLYEPKTFPEKAEKVLLEPYFQGRKYC
                     IALKEKGILYKRLIKLDKKRATKRKRPINWSYERKKAIEDAKKRVGKNPLNIDKYYYK
                     EHFKDGIEQYKGRDKDVNLLTSKEFENYKLMLNVCTDLGINPVVVLIPSMDKFYNLTG
                     ISEKERNQYYDKAQKIAESKGFEVLNLKDKGSDKYYLRDVMHLGTKGWVDVCERLFKI
                     FKEQ"
     gene            complement(18006..19025)
                     /locus_tag="PC466_002636"
     CDS             complement(18006..19025)
                     /locus_tag="PC466_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HDF2770003.1"
                     /translation="MMGKIRFGIVGTSNIANIFLRAASRVKDFELVAVYSRNLEKARE
                     FGTLHGASIFFDDLEQMAKSKDIDAVYIASPNALHSKQAITCLKHKKHVLCEKSLASN
                     LKEVKSMIKTAKDNNVLLMEAMRITCVPNFKAVKENLYKIGKIRRFFGSYCQYSSRYD
                     KYKNGIIENAFKKELSNGALMDIGVYCIHPMVNLFGAPKTVKAVSHILQTGVDGEGSA
                     VFQYDDMDAIIQYSKVADSYIPSEIQGEEGSIIIEKLNLFEKAIIKYRDGREEDISIP
                     KEKAEEKPREIEGMYYELVEFISLINNNKIESNINSHENSIIVMEIMDEIRRQSSIVY
                     PADSI"
     gene            complement(19201..19740)
                     /locus_tag="PC466_002637"
     CDS             complement(19201..19740)
                     /locus_tag="PC466_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative ABC transporter permease"
                     /protein_id="HDF2770004.1"
                     /translation="MDNVGSLLYFLFNFFLYGFIGWIIENLYSYYKQGHFQEDGFLNG
                     PFKPMYAIAMSIIIEVSRFIDPNNIFALLLLCLVVPTVVEYITGILMKVYFNKVYWDY
                     SDYKYNSRGIVCLKFSVYWTILTFIGVRYFQVYIVDSLYSLIIPYWPILVTILLVTLF
                     VDEILTIKFLRGNKDIVER"
     gene            complement(19841..20521)
                     /locus_tag="PC466_002638"
     CDS             complement(19841..20521)
                     /locus_tag="PC466_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HDF2770005.1"
                     /translation="MQKVEGIIFDMDGVLFDSERISLEFWMETFEKYGYTMTKEIYTS
                     VMGRNRKGIIEGLTDIYDSSVPIIDLYDEKTKNMIEFMERKGAPIKLGVNELISFLKE
                     NGYKMAVATSTKRERAVKRLAKANLKDYFDAIVCGDDVVNSKPNPEIFLKAAKKINVN
                     PQNCIVIEDSPMGVEAAYNGGIRCINVPDLKEPDEQIKSQSHKILENLLEVREYLKSL
                     NSKECHNL"
     gene            complement(20550..21839)
                     /locus_tag="PC466_002639"
     CDS             complement(20550..21839)
                     /locus_tag="PC466_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HDF2770006.1"
                     /translation="MRELLKVTLIVMLVLINAFFVACEFAMVKLRSSRIDTMITEGNN
                     NAKRCKIIKDNLNSYLSACQLGITLCSLALGWMGESTVKELILPIVSVFNLSESIIYT
                     ISISISFLIITMMEVVIGELVPKALALYNTEKIMLSTSFLLVGFYKLTYPIIYFFNLS
                     TDLFLKPFGYSQADEVDEPHTGDEIRLLVEESYKSGLIDESEQRLVDNIFEFEEKKIR
                     EIMVPRTDMVCIYESDSEEKILAILKEEGVTRYPVCRKNKDDILGFVHIRDLYNQKIN
                     ENKIELEEILRDIIYISENLTIDKALERIRKEKLQLAIVVDEYGGTSGVVTIEDILEE
                     IVGEIQDEFDKEETHIKKIGAGSYLVDGTESINYINKYFGLDIEHDGFDSIGGWISYM
                     LGSNIKVNQSVTFENYNFTILELDKLRVVKLIIKSVI"
BASE COUNT         7174 a         3790 c         2258 g         8712 t
ORIGIN      
        1 tattttttat tacttctata ttattgtatt gcttaaaaat acataattta actcttattt
       61 aataacagaa actcccatat atggtcttaa aacttcagga acaaccacag aaccatcttc
      121 ttgttgataa ttttctaata tagctgcaac acttcttcca atagctaacc cagagccatt
      181 taatgtgtgt acatattcag ctttagaatc tttatctctt ttaaatctta ttcctgctct
      241 tctagcttgg aaatcttcgc agtttgaaca agatgaaatc tcaacatacc tattgtaact
      301 tggcatccaa acttctacat catatttaaa agaagccgta aatcctaaat cacctgtaca
      361 tatctttact actctataag gcagattcaa taattgtagc atagtttccg cattgttagt
      421 aagcttttct aactcattgt aagattcttc tggtgcaact attttaacca tttctacttt
      481 gttaaactga tgctgtctta ctaaacctct tgtatctctt ccagcagaac cagcttctga
      541 cctaaaacat ggagtataag ctgtataatt tattggtaat tgttcaaatt taagtatttc
      601 attagcatgt atattagtta aaggaacttc tgatgttgga atcataaaat agtccagacc
      661 ttctatttta aacatatctt cttcaaactt aggtaactgt cctgtaccta aaaaactatt
      721 tctatttgcc ataaatggtg gaatgacttc tgtatatcca tttacttttg tattcgtgtc
      781 taagtaaaaa tttaataatg ctctctctaa tctagcaccc aatcctttgt aaagagtgaa
      841 tcttgaacca gttattttac tcgctgtttc aaaatcaagt atacctaatt ctgttccaat
      901 ttcccaatga gccttagatt caaaatcaaa ggtagtagtc tttccccaag ttcttacctc
      961 aacattatct tcatcagttt caccttgtgg tacttctgga tgtggtacat ttggtattct
     1021 cattaatagg tattccatct tatcttctac ttctttaaga ttttggtcta ttaccttaat
     1081 tttatcagat aactctttta gtttaatctt ttcattttct acatctttac cttcttttat
     1141 aagatttggt atatttttag atgctgtatt taatttatgt ttcataactt caacttcttg
     1201 aagaatcttt cttctttcat catctaactt aactacttca tcaaggttaa agtctttttc
     1261 gccccttctt tccattgctt tttttataca atctaaattt tctcttattc tttttatatc
     1321 aagcattttt tcctcctcag tacctaagat tggatttatc tcttaatctc aaataactta
     1381 gataatatac tttatgcttg aggttaagaa acctttttct ttatccgaac ctgttatttt
     1441 tattttattt atattttact cacttttttg tccattgtca aattatattt aattaaataa
     1501 atgaaattta attttaggag aatattgcta gatttaactt cattataatt atatctattt
     1561 tgctaatcaa ttatctattt tgactttttc tttatcaatc ttgtatagtt attaactttt
     1621 atataaattt ttttatatta taacatagtc ctatatatct attatttgga tagaattatt
     1681 ttttaaatta gaattatttt aatgaatgct tcaagtaata ggtatgaaat tgaatctttt
     1741 agaactgctt ataaaaaata ctcaaagaaa aatagtaatt ttctcagatt cacaatatat
     1801 tttatatgaa atgttataag gtaatctatt taataaattt aaatttgcta ttatagattt
     1861 agttccaaag tcttactgca aagtaatata catagttttt taataaacta ataagtgcaa
     1921 ttaataacta cttaattgtt taatatagta catagataac tttaataaat cgacagttat
     1981 ttaaaaaggt agaatcaata aaattatact tataaatctt caatacaata attaaaattt
     2041 aataaaaaat ataattgttg atttaactgt aatcttattt aattctacct aacttattat
     2101 ataaaactat tttttataga ttataaaata tctaactttc atctacttca aagaatacaa
     2161 tacttctcct tctcttatag tctgcaatac tttaatatct tttattttca tagggtcgat
     2221 tgtaagtggg ttttcatcta atattatcaa attagctaat ttaccttctt taattgaacc
     2281 ttttttatct tcttcaaaat attgatatgc tgcatttata gtaacaccct ttaaagcatc
     2341 taatgggctt atcttttcat tctctcctat ttgtatacct ttttttgtaa ttctatttac
     2401 agcacaccat actgtttcca gcatattagg tgctattact ggtgtatcct gatgaagagt
     2461 gtaaattaat cccttttcta tagttgtttt aagtgggcta atcttaaacg ctctatcttc
     2521 tccaaggttt ttgatatgaa tatcacccca ataatatgtg tgagctacaa agtatgaagg
     2581 tatcatattt attactttca tatcatcaat ctggtctgct cttactgttt gagcatgtat
     2641 cataactggt cttatattat tttcactact ttgctctttt aagtttaaaa ctttctcaaa
     2701 cgcatctatc aactggtctg ctgctgcatc tccattacaa tgagttaaga gttgcatctt
     2761 ttcttttagt gaaatatcta taaacttttc tacttcttca tctttgtata taggatatcc
     2821 acaataacca tcatctgaat tttcatatgg tctactcaac catgctgtct taccttgtgg
     2881 agaaccatct aagaaaatct tataacctcc tactttaaat ctatttatat atttttttat
     2941 aaactcccta ttattatcta atacagactt actttttttc aaatttacat atcctacaac
     3001 atccattttt aatttatttt gatttgccat tgcttttaaa atgttaaatt gattttcttc
     3061 cattaaacct tcttgagctg ttgtaatacc atagcttaga tatatgttct gtgctttttc
     3121 aattgaatta aaaatctcat ttgatgatgg ttgttttatt ttagatgcta cattaaaaaa
     3181 tgcattttct tctaaatatc catttggttc ttcactgcct tctactctac ctatatgtcc
     3241 accttctggg tcacgtgttt cattggtaac accaagctgt tttaacccca atgtatttgc
     3301 agctcccata tgaccagaag catgtgaaat tagtattgga ttttctgaag atgcactatc
     3361 gagtacactc ttatctggat gcttattttc ttctaaaaaa ttattatcat atgaaaatcc
     3421 aattatccag tctccttttt ttatattatt cgactctttg aaatcctgta ttttttttac
     3481 tatgtcttta aaactggttg catcttctaa aggaactagc tttagagtag tagcaaaagc
     3541 tatcaagtga ctatgtgaat ctataaaaga tggcatcaat gtcttacctt gtaaatctat
     3601 aatttctgta tctttatttt tcaaagcaaa tacttcttct tttgttccta tcttttttat
     3661 tattttatct tttataagaa tagcatctcc acatattgaa tcttccattg tgatgatatt
     3721 tccattgtaa taaatttttt ctttcataaa attctcctta cgttgtctac tttaataaat
     3781 ttttttcatt attttctgct taattatatt atcttcttta taaacttttt ctttagagtt
     3841 taatcatata aaagttttat ttttaattat tgtttgccaa gaagtaaata ctattcattg
     3901 taaataagac aaattaatag gctttatact aattgaaaaa atattataag ttgttaaatt
     3961 taaatatcta aactcaatta tatctgtaca attgtaattt tttaaatcat gatgtattat
     4021 tttaaatata cagttacatt attattcaca atataagtat cttagttctc aaataacatc
     4081 tcatgtaatc tattcaatgc aaaaaattta aatatttttt aggaggtttt ttatgagcaa
     4141 ggaaaataaa aatgtaagaa ttgctgttgt ccaggcgtca ccagtcataa tggatttaga
     4201 aaaaactgtt gaaaaagcat taggattaat taaagaagct ggtagaaaag gggcaaatat
     4261 cgtagttttc cctgaagcat tcatacctgc atatccaaga ggtctttcat ttggatttgt
     4321 tgttggaagt agaacaatgg aaggtagaga agattggaaa agatactatg ataattctgt
     4381 accagttcct agtgctacaa cagatttatt aggaaaagca gcacaagaag caggagtata
     4441 tctatcaatg ggtataacag aaagagatgg taatgatata aattgtaccc tttattgcac
     4501 aaacttattt ttctctccag aaggtaagct aattggtaaa cacagaaaac ttaaacctac
     4561 aggaacagaa agatgtattt ggggagaagg agatggaagt actcttacag tagttgatac
     4621 tccatatgga aaaatgggtt cgttgatttg ttgggaaaat tatatgccat tagctagaac
     4681 agttctttat gctaagggtg taaaacttta catagcccct actgcagatt caagagaaga
     4741 gtggcaagca actatgaagc atattgcttt agaaggaaga tgttttgtaa ttggatgcaa
     4801 tcaatatgtt gaaaaaaata tgtatccaac tgaccttaac tactataagg agctagatgc
     4861 agaaccagaa attatgtgtc caggaggaag ttgtatagtt gacccttttg gaaaatatgt
     4921 agcaggtcct attttcaata aagaagaaat gctaatagct gatttagacc tagaaaaaat
     4981 agtacttagt agactagatt ttgattcaga aggtcactat tcaagaccag atgtatttga
     5041 attaattgtt catgaataat ctttttacac aaacatctac ataaattttt ttacataaaa
     5101 aaatgagata ctcataagta aatttcaagt atctcatttt tgcttaaaac ctataatcct
     5161 aattataaat ttattcgcct atattttttc taaatcaact actgttcttc caacatgttt
     5221 tcctgtcatt atcgaatcta tactatcatt taactcttcc aatgatacta catttaccat
     5281 atcatctaaa tcatctaatt tccattcatt tgataataaa tcccatattt ttaatcttaa
     5341 gttcattggg caatccacag aatctatacc atataaagta attcccttta agataaatgg
     5401 atatactgaa cttgtaaaat caactcctcc tgcattacca caagttgtta ctgctccaca
     5461 ataattagtt gtctttattg ctgttgctag agtatttcct cctactgtat ctattactcc
     5521 agcccatctt ggtctaagca gaggtcttcc tgagttatca tccacttctg acctatgtat
     5581 aacatcttta acacctaagt ttagtaatac ttctttttgt tcttctaatt ttcctgttga
     5641 aactacaact gaataaccta atttaatcaa tattttagtt gcaattacag caactcctcc
     5701 agtaccacca gtgactaata catctcccat attcttgtct acagaatcta taaatttata
     5761 cacagataaa gctgctgtaa accctgctgt accataatcc attgcttctt ttagtgaaag
     5821 atttttagga agtttaacta cccaactaga aggaactctt atgtattctg aaaaaccacc
     5881 agaagtattc attcccaagt cataacctgt tactaaaact tcttctccaa ttttaaaatc
     5941 atcacaacta ctagattcta ctataccaga tgcatcaatt cctggtgtat gaggatactt
     6001 tctcgtaaca cccttattac catttgcaga aagtgcatcc ttgtaattta gagaagaata
     6061 ttttactttt attagaactt cgccttctgg caatgtatct acttctcttt caactatatt
     6121 tcttctaaaa tttccttctt cttctgtaat atatagtgat ttaaattttt tattcataaa
     6181 tttcctccca atacatttag ttttatgtta aactaattat agtttataaa tagttttatg
     6241 tcaaactaat ttaaatagat taaagattgg agaataattt atggaagata aatatattgt
     6301 acatttcata agtaaaacaa aggctagtat gattaaattc attgaaaata aactcagtaa
     6361 aaatggttta ggtgagttaa tacctactca tggaaatatt ttaactgcac tttatgaaaa
     6421 taatggaata cttacaatga aagaaattgc agctaaaata ggaaaagata aatccactgt
     6481 tacagtgttg gttaataaac ttataaacct aggatattta gaaagacaaa aatgtacaaa
     6541 tgacaaacgt atcacgtata taaagcttac aaaaaaggca ctgcttatag aagatacttt
     6601 taatagcatc tcaacacaag ttaaagagac agcataccat aatattacag aaaatgaaaa
     6661 acaagaattt cttagaattt taaaaaaaat taatgataat tttaaaaatg ctgactaaat
     6721 tgagcataat tatatctcct attggaataa taaataaaaa gaatcaaata ttgtaaaaat
     6781 ttattatgat agagaggtag aatatgaatt taaaagatag taaaactaaa gaaaatttat
     6841 taagagcttt tgcaggtgag agtcaagcta gaaatagata caatatttct gcatctgtag
     6901 caaaaaaaga aggattatat ataatagagt ctttatttaa ttacactgct gaccaagaaa
     6961 aatcacatgc aaaacaattc ttttctaaat taaaagaatt tgctggtgaa aatataagta
     7021 tatcaggagc ataccctgta gatttatatg acaagacagc acaacacctt aaagctgcac
     7081 aacataatga gcttcaagag tgggatgatg tatataaaaa ctttggaaaa acagcacgtg
     7141 aagaaggatt tgaatctata gctaagttat ttgaaaatat agctgaaata gaaaaagttc
     7201 atggtgatag atttggtaga tatgctactg atttagaaga aggtacttta ttcagaagaa
     7261 atgaagatat acaatggata tgtacacatt gtggccatat acatataggt aaagaagctc
     7321 caaaagcttg tcctgtatgt cttcatccac aaggatattt cttagatttt aaaaactcat
     7381 tatttgaata aactaaggca ataattctat ttaaacaatt tactatattt atatcaagta
     7441 tttttataaa tactgtatta tcttaataac aataaaatga accattgata ttactataag
     7501 tagaaaatgt agtttaaata caatttatag taattcatca tggttcattt tattatttac
     7561 taatccctat aacctactta aatctatctt taacttttac atactcacat aaaatcttat
     7621 ctttaaacta aatatttaaa taaagtgtat tttaagtaga ttattataat acattatata
     7681 agataataca ctatgataac tttatactta tatcatttat ttcttttgtc aagtcaatct
     7741 caataatctt aactacatct ttttcaaact ttactttttt ataatccaga catcctacta
     7801 cgaatggaac tccaaacttt ctaaacaaat aaatctttcc actttcattg tatattgatg
     7861 taaaattttc ttctattata ttcactatca attttaactc ttcaaaagtt attatagatt
     7921 taactaaaaa cttctctatt atgctcaata taagcagttc ttttttacct atgctttgct
     7981 cttttttata taaattttga aatatttctt tggtataatt acatataact tctttactga
     8041 gaataaaatc aatgtcaaat tccttattaa tatccttttt cataaacata tttgcaatat
     8101 catcaagaga agtctcttct ttcatagaca atattaactc tattctttct agtattttat
     8161 ctcttggaaa gaaagtctct tgacctgtaa aagctgattt ttttataaac cattcctctg
     8221 gtattatgtt ttttcttttc catctatata attgaccata agatatatta gttttgctca
     8281 ataaatcttt cttagatatt aattcttcca taacttttct agcccacctt tatactgttt
     8341 tttacagtag aattatctga aactgataaa ttatcactgt attcaatatt tccaacgtca
     8401 caattatcta ctagagatat gcttttgcct cgtatatctt ttattgatgc atcttctaat
     8461 tcaatagtat ctccctctat caaattacat ttaaactttc ctgaaaaaat attaatgatt
     8521 ttaattaatg aaaaagcatc tttgcttctt cctattttta tattagttgc ccctatctct
     8581 ttacaataag aacctcctcc tgaataaaca tatatatttt ctccatttaa aagaccatca
     8641 cattttatta ctccatatac ctttatatct tcacattcta tatttgattt atttctcatt
     8701 tcgccataga tttttatatc ttgtgcatac atattttcat ttacacttaa ttgtcctctt
     8761 attgtaacat tattacattt aagtttgcca tccactttct gttgagcagt tataactaag
     8821 tcatctattt ctgcatctcc ctctatatta agttgaccat tcactcttac acgctctgct
     8881 ttaagattgc ctcttataat agtttttccg ttaacaacaa aattttttat attgatgtca
     8941 ccttcaaatt ttgcatctcc aaggactttt acttcgttac ttttaacatt tccttttgat
     9001 ttagaacttc ccacgatttt tatattttca tactcaccac tacttataaa gccttctcca
     9061 agtattttta tagacccttt ttccatatta ttacctcatt ttaaatttta tttttaaacc
     9121 tatttattac ttatccttct ttaattttat tttttcactt atattcttta tttcaccaac
     9181 tattgaatct tcatcaatct ctatactttc actgtactcc aaactttcta cataacatcc
     9241 cttgcctatt ttaatatttt ttcctcttac aactttgact tcactatttt ctaagcttat
     9301 ttcatctgct tctataatat ttgcaaacaa tttactttct gtatactttc taattgataa
     9361 tagacctaaa cttattaaat ttgaagacac tttttcaaag ttgatatgct ttttttctag
     9421 catacgaaat tttttgcaat aatctccatg cccctttttt atatttatac tacttgctcc
     9481 aacttcatta aaattagaag ttccatttaa actaatatta acttcttcac aattcaaaaa
     9541 tccattacac tccaagattc cacttaaatt gatattttca caatctatat tctcatttgc
     9601 ttttaaatat ccttctccat gaataatatc cgattttata cttccttcta cattaataat
     9661 tccactagta tcaatttcaa cagaattaat atttcctgta catctaagaa gtcccgatat
     9721 ctcaactttt gatgccagta tgtttccttc tactttactt aaaccagatg taaaaaattc
     9781 attacattct gttgtcccaa aaacttttgc tgaaccagaa gaatcaaatt tactacattt
     9841 tacacttcct tctattttgc ctgttcctga tatattaaca ttatcaaaaa ttccaccttt
     9901 acattttcca acaccatcaa atcttagtga acttaattct tcattcataa tgatatcctt
     9961 tctttaccgt attttatctt taaacctaat ataacaaaac attgttacgt tgtcaagtct
    10021 gataataata cttaataaag caactatcat ttattttcta taaataggca taaaaataat
    10081 agggaaatgc tttatttaaa ctagaaatct aatttcttag attgtggttt aaataaaata
    10141 tatccctatt actcaatctt tatatattca ttgtataaac ttctaaaata taagtcttta
    10201 aattctactg tcaatacttt ttatacactg tttgtgctat catttcacac ctaaaggagt
    10261 aggctctccg cactattctg taacctaaaa gacactatct tcttctatct attgataaat
    10321 ttttctatta catcagctag tctctccata tcagttggat aaacttcacc tatgctacct
    10381 attctaaatg tatctatatc agtcaattta cctggataga taacaaatcc attatctttt
    10441 aaataagtat aaaattccat aaattcaaac tttgcatttt taggatataa gaaagttgtt
    10501 attacaggtg attgagcatt atcattcacc aaagtatcaa atcctaaaga ttttaatctt
    10561 gaagctattg taaactgatt ttctttatat ctagcatatc ttttttcaac agaaccttct
    10621 tcttccaatt ctaataaagc ttgataaaaa gctcttacaa catgtgtagg tgaagtaaat
    10681 ctccatttac cattattttt ctccatagtc tcccattgcg catacacatc aagagataat
    10741 gatttagcta tacctttaca tttagataat ttctctttat tagctattat aaaaccaaat
    10801 ccaggtactc cttgtataca tttgttagaa ctactaacta aaaaatctat attaaaatct
    10861 tcaacatcaa tctcaattcc cccaaaacta ctcatagcat caactatata aattttgtta
    10921 tattcttttg caagtttccc tacctcttgt ataggattta atctacctgt agtagtttca
    10981 cagtgaacca ttgatatatg tgttatatcc ttgttttctt ttaataaatt ttctactaca
    11041 tttaaatcca ctgcttctat atctttaaat gtgcagtcaa caaattctat gttaagataa
    11101 ttacatatat ctttcattct ctttccatat gctccatttg caattacaag aagtttacca
    11161 tcttttgaaa tagtacttcc tattatagct tctactgaaa aagtcccact tccttgcatt
    11221 aatacacttg tgtatttatc tgtattttgg gttgctagag atactaatct tcttctaaca
    11281 tcttgtacta ggttattata ttcaacatcc caagtacacc aatcttttaa catagatgct
    11341 cttactgatt tagtagtaga tagtggtcct ggtgtaagta atatgtaatc attttctggt
    11401 acaaaatctg atttaatagt ttcattctct atttttatta gtatatcttc taactcagcc
    11461 atagtttcta ttacaaaatg tgcacctgcc tctttaaatt tctttgaaac tatactcatc
    11521 ttagctttta attcttcctt atccatgttc tctacttctt cttgtgtaag ccctaactca
    11581 cttgaacctt ttattacagc aacactccac attcctgcat ttacgccttc ttttacatca
    11641 cttattgtat ctcctacttt taccatagaa ctcataggag acacccctaa agcttcagca
    11701 tttttatagc acatccaagg atacggtctt ccttgagata cttctgatgg tgttacaaga
    11761 aaatcgggtg agtatccttt ctttgctgca tttggttcaa ctatgttcat catctctctt
    11821 gtataacccg ttgtagaacc tatttttaat ccattttttc tcaacttttc aatagtttca
    11881 acaacatgag gaattggagt cgtatactct tctaatgtct caaataacat tggctcaaat
    11941 tcagcataaa gttcatttac atcatcttca gttggcactt taccaaactt atctgaccaa
    12001 agatttttta ttctatccat ttcacacatt tctcttatat ggtctatttt taattttccc
    12061 ataggttttc ttgcttcttc cattgttaca tctatacctc ttcttttaaa tatctctata
    12121 aatacattaa gaggtgcaaa acatccataa tctactgttg ttccagccca atcgaatact
    12181 actgctttta ttttttctcc atatatcttt ttcatattta tagcctccat agattcattt
    12241 tagaattttt gtgtttttaa ttgtttttac ttttaaagta taactttcat atgttaatta
    12301 tacatcatat ttaggttaaa tatatattaa atttctgttt ttagttgtat ttaattgttt
    12361 ttattttata tcatatttcc ataaaatcct aagttacaat ctaaaattta ctttctaatc
    12421 ttaatctatg aactgactat attttatgaa tttagttgta ttaagcatag ttgtattata
    12481 taaaactaag ggtttatttt gcttctatcc atgttatatt tatctcattt aacttatcct
    12541 tccattcatt cggaggttct acatcacaaa taacaaaatc taattcctct aaatctgcta
    12601 tcttatacat actagcaatt cctattttag aactatcaca taatacaaaa ctttcctttg
    12661 aattttttat atattctttt gacaacaatg ccttattttg gtctatacta ctaattccaa
    12721 aactatcaag tataccttca ctagatataa aagctttatc tacgtataag tttttcatag
    12781 tgtctattga cattggacat gctgtccttt ggtgttttaa atttactttt ccaccaataa
    12841 atataacttc tccatcaaac aaaccttgat tctcataaga aatcaatttt gatagaactg
    12901 gataagagtt tgtaataatt tttaaattgt ttacagatat tatataatct acaatctgca
    12961 aattggtagt accttcatct atgataattg actcattgtc atttacaaac ttagctgcgt
    13021 atttagcaat actttgtttt ttatctaggt tagtattgtt tctctttata tgttctggtt
    13081 caatcactcc ataatttatt tttatagcac caccatatac cttttttaat ttattttcat
    13141 tttctaattc ttccaaatat cttcttattg tttctgatga tacttctaat ctttttacta
    13201 attctttagt atttaccttc ccttttgaat ctaataattt aagtatttct ttttttctat
    13261 ctatcgaatt taaagacatt cattttcctc ctaaatataa tatatttttc tcctataata
    13321 ttacaatgat acctaagatt tatgaaatca tatttatgta ttaaattttt tacttaatta
    13381 aagttatttt caaaagactt tgtattatca ttaaaaaagt ccatcaaata ttagtatcag
    13441 atggactttg taaaatttta ttttataaat taatatttaa agtctaacta ctaatttatt
    13501 ttcttgtctc caagaatttt actaaattat ttacagtaga catatctttt ctctctaaat
    13561 cagttggttg aagctctatc cctaatctat tttcaatttc aagtaaaact tcaattatag
    13621 ctaatgagtc taaaagttcc gtctcaaata aattaaggtc taaatcttct cttatctcat
    13681 cagtccctaa tacatcttca aatatttcta taactgtttc ttgcataaat tttcctcctt
    13741 aaaattaagc taaataacct gagaatatca gcaatccaaa acacacaata tggaatgtaa
    13801 tgaaaatctg cactctctcg aaccatttat cttttttatg ttttttataa aatttagatt
    13861 ttcgctgata tatatcagtt aacacaagtg ccaatccttg gtatacacca taagcaacat
    13921 aataccaagt tagaccatgc caaaatccca ttgttatcat ggttatcatc tgagccacat
    13981 gagcagcagt agtccttttc ttaaatcttt tctttctcat tgatgacata acaaatctag
    14041 aaaaaatata atctccaaac catcttgaaa gacttatatg ccatcttgtc cagaactctt
    14101 tcatatcttt actgataaat ggcttgtcaa agtttatagg tacttgtatt ccaaatatgt
    14161 accctgtacc tatagcaaat aaactatatc ctgcaaaatc aaagaacagg tataaactat
    14221 atgcgtacat ataacttaaa atatttataa aactcatatc tttaggtatt cttgataccc
    14281 aatatgtatt tatcaaaaat gctataacaa acttataacc tactcccatg acaatatttt
    14341 ttattcctgg cagtaagtat tcttctatat actcttttct agagatgtgt ttttccaagt
    14401 cctgttcaaa tcttcttgac ctatcaatag gtccagaact taaagttgga aaaaataaca
    14461 taaaataaag catctttgaa attttaactt cttttatagc tccatcataa atttcaataa
    14521 ccatttgtat agttctgaaa tttaagtatg atattccaat aaatccaatt attccaaaag
    14581 aagtaactgg agatatttta tttattatta ttgggagcat tgatgcaaac aagaatcccc
    14641 aatatatgta tttattttta gtttttcttc ttacatattc atatccttta actattatta
    14701 cttcaagaat aataaatatt accaaatact ttagctggac atcaattcct actattaaga
    14761 atatcataaa caaacttgcc aacataccat aatactttat attcttgccc attagaccta
    14821 aaattactgc tggtattgat gttaataata atatataaag ataaaaataa tctccatact
    14881 gtgaaaaaat cattaaattt cctccataag tttctttctg tctattttac cattgatatt
    14941 tgttggaaac tcagagatta ttgaaatatt tcttggaatc atatatgaag gtatatactt
    15001 tccaagttcc ttttttatta tcatcccatt tttaatatta cttaaatcat tcttttcatt
    15061 taactcaaca atacctttta agtaagcaat tttttcgtcc ttatatactg gtaaaactac
    15121 tgcatttttt acattatgta cttttctcaa attattttct atatcttcta tttcaattct
    15181 aaatccattt aatttaatct gaaaatcttt tcttccacaa taatatatat ttccatctaa
    15241 aagatatccc atatctccag ttttataagc tctccacttt acaccatcta tttcatcata
    15301 gaaaaatact tcatcagtct tttctttatt attgaagtaa cctttagaaa ctgatggtcc
    15361 aattattata atttcaccct tttcattttc tttaagttca tttccatctt catcaagtat
    15421 ttttatttta caatttgaca tagggtatcc aactggaaga cttttttcat catctatagc
    15481 tttttgagtc atatcattta cacttacacc aacagtagcc tcggttggtc catatccatt
    15541 gataattctt gtgtttggaa atctactcat aagttcttta gtaagatttt ttgaaagtgc
    15601 ttctcctatg aatatcattg actcaaggtt aggaagcatt ttactattaa actctttttc
    15661 agttatacat actcctgcaa aagaaggagt tgacacccat acagctatat ctgagatact
    15721 aaattgtcta aatagttctt tatagtctgc taatacatct tttgatattg aaaataatgt
    15781 agctccatgg ataagaccag ggtatattgt tgtaactgaa aggtcaaaag aatatgctgg
    15841 ttggttcatt attacttttt cacttccatc tatgtttaga tatgggctta tccaatctga
    15901 aaagctatct aaattgtttg aacttatttg aacccctttt ggctttcctg tacttcctga
    15961 agtaaatagt atatatgcat tttcatcatc ttttacccag ttttctttat ctaatgattt
    16021 tccctgatat tcatttatta tatcatttaa tttatccata tcaattacat tgatatctcc
    16081 aaaatttctt tcatcactaa aattaaatat tacttttggt tttatctctt tagtgacttc
    16141 aaaaactcta tcaattggaa aactaatatc aagaggcaca tacgctctac ctgattttaa
    16201 agctcctatc atacatgcca ttatcatgtt ttctttattt ccataaatta ctataggagt
    16261 atcctcttct ttgtatacat cctttagaaa tactgatata gcatctgaat attcatttaa
    16321 atctttataa gaaagtttat ctccattaca cattagtgct gttctatctg tatttgaata
    16381 tttttttatt ccttcaataa ttttcatata agaatgctcc tttaaaatcc gttataaata
    16441 aatggcaatt ctttaaatgg agtaaatgtt agaactccta tcgccaatat tataaccata
    16501 gttaaacaaa tactagttaa caaatcttta ttgttcttta aatattttaa ataatctctc
    16561 acagacatct acccatcctt tcgtaccaag atgcattaca tcccttaaat aatacttatc
    16621 tgacccttta tctttaaggt ttagaacttc aaagcctttg ctttctgcta ttttttgtgc
    16681 tttatcgtag tactgatttc tttctttttc agaaatacca gtcaaattat agaatttatc
    16741 catacttggg attaatacaa caactggatt aatacctaag tcagtacata catttagcat
    16801 cagtttataa ttttcaaact ccttagatgt taataaattt acatctttgt ctcttccttt
    16861 gtattgctct ataccatctt taaaatgctc tttataatag tacttatcaa tatttagtgg
    16921 atttttacca actctttttt tagcatcttc aatggctttc tttctctcat atgaccaatt
    16981 tattggtctt tttctttttg ttgctctctt tttatctagc ttaattaatc gtttataaag
    17041 aatacccttt tctttaagag ctatacagta ctttcttcct tgaaaataag gctctaaaag
    17101 caccttttca gctttttcag gaaatgtctt aggttcatat agcttagcat ataatgcttc
    17161 tgctttatac tcatcacttc cccataatag cttacttgat ttttttgcat attcaatctt
    17221 attttgttta gatatttttg gattatctaa aaatcgataa aattgtattg gtgaaaatct
    17281 agactgataa tggtgacttg tgactccgtc tttttccata aaccattgca tagaaattaa
    17341 caagacaact ttcttattat caatattagg attcatactt cctaatattg cagcatcttg
    17401 taatgtctga gtataggctc tcccaattgc aaacacctta tttttactcc tatttgtatt
    17461 aaaatagtac tttggatgtt gttttgttga attactaagt tctgatgacc ccaaaatcat
    17521 aatatccttt tctcttaaaa aatgattatt tgctgtaacc cctttatctt ttatatcact
    17581 taaagtatca tccataattg gaagtagatt tttctccctc aaaagttcat cagttttaga
    17641 atcaagaaat ttgtctaacc caaataaaaa tactacgcct attataaaag gtgtaataaa
    17701 gtatatcaat tttctcatat tttctctcct ctaaaaatat tcaaatttat gttattatta
    17761 atcatattag ttttgatatg tatattcaac tacaaaattg taataaaatc gtcaaaactt
    17821 tttttgatac tgttacaaaa ttgtaaaaaa aaagaaaaaa acaccaaaaa taaatttctt
    17881 tttagcactt tttcatactt ataatttgac attttaacac ttggctaagt atacacctta
    17941 ccttaactta aaattaaatt tatttaagaa tatatattat aaattcttat attttctaat
    18001 ataagctata tactatcagc tggataaaca atactacttt gtcttcttat ctcatccata
    18061 atttccatta ctattattga attttcatga gaatttatat ttgattctat tttattgtta
    18121 tttataagac ttataaactc tacaagttca taatacattc cttctatttc tctaggcttt
    18181 tcctctgctt tttcttttgg aatagatata tcttcttctc ttccatctct gtatttaata
    18241 atagcttttt caaatagatt aagcttttca attattatac ttccctcttc tccttgtatt
    18301 tcagatggta tataagaatc agctacttta gaatactgaa ttattgcatc catatcatca
    18361 tattgaaata cagctgaacc ttctccatcc actccagttt gaagtatatg agaaactgcc
    18421 tttacagttt ttggagcacc aaataaattc accataggat gtatacaata cactcctata
    18481 tccattaaag ctccatttga caactctttt ttaaaggcat tttctataat tccattttta
    18541 tatttatcat atcttgaaga atactgacaa tagcttccaa aaaatcttct tattttccct
    18601 attttataca agttttcttt aactgcttta aagtttggaa cacatgtaat tctcatagct
    18661 tccataagca atacattatt atctttggct gtttttatca ttgatttgac ttcttttaaa
    18721 ttagatgcta acgacttttc acaaagcaca tgttttttgt gttttaaaca agtaatggct
    18781 tgctttgaat gtaatgcatt tggagaagct atatatacag catctatatc cttcgattta
    18841 gccatttgtt ctaaatcatc aaaaaaaata cttgctccat gtagagttcc aaattctcta
    18901 gctttttcta aatttctaga atatacagca accaattcaa aatctttaac cctagatgca
    18961 gctcttagaa atatatttgc tatattgctt gtcccaacaa taccaaatct tattttaccc
    19021 atcataaatc actccccatt ttctacactt tattttaatt ttaataaaaa actttacaac
    19081 ttatagatat attataaaat aattttatca aataaaaaag aaagctaatt ttaaatgatt
    19141 tcaccatttt aacatagctt tcttttaact acaatctaaa ttcaacttat atttttaaag
    19201 ttatctttct actatatctt tatttcccct caaaaatttt atagtaagaa tttcatccac
    19261 aaacaatgtt actaaaagta tagttacaag aattggccaa taaggtatta taagactata
    19321 taaactatca actatataca cttgaaaata tctaactcca ataaatgtca atatagtcca
    19381 atatacagaa aactttagac atactattcc tctactattg tacttataat ctgaataatc
    19441 ccaatagacc ttattaaaat atactttcat aagtattcct gtaatatatt ctactactgt
    19501 cggcactact agacataata aaagcaatgc aaatatatta ttggggtcaa taaatcttga
    19561 gacctctatt ataatcgaca ttgcaattgc atacattggt ttaaatggac catttaaaaa
    19621 tccatcttct tgaaaatgcc cttgtttata ataactatat aagttttcaa ttatccaacc
    19681 tataaaacca tacaagaaaa aattaaataa aaaatataat agagaaccta cattatccat
    19741 gaatattcct cctagctgtt tatacttatt ttttctcata ttcatggatt tattctaaat
    19801 caaagaaatt atatttaatt tatttaatta atactttata ttatagattg tgacattctt
    19861 tagagttcaa actttttagg tattctctaa cttccagtaa attttcaagt atcttatgtg
    19921 attgtgattt aatttgctca tctggctctt ttaaatctgg tacatttata catcttatcc
    19981 caccattgta tgcagcttca actcccatag gcgaatcctc tatgacaata caattttggg
    20041 gattaacatt tatcttttta gctgctttta agaatatctc agggtttggt ttagagttta
    20101 caacatcatc tccacaaact atagcatcaa agtaatcttt taaatttgcc ttagctaatc
    20161 tctttactgc tctttctctc tttgttgatg ttgcaacagc cattttgtat ccattttcct
    20221 ttaaaaaaga gattagttca ttgactccta atttgatagg agctcccttc ctctccataa
    20281 attcaatcat atttttagtt ttttcgtcat ataaatctat tattggtaca gaactatcgt
    20341 atatatctgt aagaccttct attattcctt tacgatttct tcccataact gatgtataaa
    20401 tttccttagt catagtatat ccatactttt caaacgtctc catccaaaat tcaagagaaa
    20461 ttctctctga gtcaaacaaa actccatcca tgtcaaaaat aattccttct actttttgca
    20521 tacaattcct ccaatatttt ttgatataat tatattacac tttttatgat taattttaca
    20581 accctcaatt tatccaattc taatattgta aaattgtaat tttcaaaagt tacgctttgg
    20641 tttactttaa tatttgaacc aagcatatag gatatccacc cacctatact gtcaaatcca
    20701 tcatgctcta tatcaagtcc aaaatactta ttaatatagt tgatagattc agttccatca
    20761 actaagtaag aacctgctcc tattttctta atatgagtct cttctttgtc aaattcatct
    20821 tgaatttctc caactatctc ttctagtata tcttctattg ttaccacacc agatgtacca
    20881 ccatattcat ccacaactat agcaagttga agtttttcct ttcttattct ctcaagagct
    20941 ttatctatag ttaaattttc agatatatat ataatatctc tcaatatttc ttctagttca
    21001 attttatttt catttatctt ttgattgtat aaatctctta tatgtacaaa acctaatata
    21061 tcatctttat tttttctgca tactggatat cttgtaacac cttcctcttt taaaatagct
    21121 aatatctttt cttcagaatc actttcatat atacatacca tatcagttct aggaaccatt
    21181 atctctctaa ttttcttttc ttcaaattca aaaatattat caactaatct ttgctctgat
    21241 tcatctataa gtccactttt ataactttct tctactaata gtcttatttc gtcacctgta
    21301 tggggttcat caacctcatc agcttgtgaa tatccaaatg gtttaagaaa taaatcagta
    21361 cttaagttga aaaaatatat tattggatat gttaacttat aaaatcctac taataaaaaa
    21421 gatgtactca acattatttt ttctgtatta taaagtgcta aagctttagg aaccaactct
    21481 cctattacaa cctccatcat tgttataatt aaaaaagaaa tggaaattga tatagtatat
    21541 ataatacttt cactaagatt aaatacactt actattggta aaattaactc tttaactgta
    21601 gattctccca tccaacctaa tgcaagtgaa caaagtgtta taccaagttg acatgcagaa
    21661 agataggaat ttaagttgtc ttttattatt ttacatcttt ttgcattatt attaccttca
    21721 gttatcatgg tatcaatcct agaactacga agttttacca tagcaaattc acaagctaca
    21781 aaaaaagcat ttatcaaaac aagcattact ataagtgtta cttttaataa ctcccgcata
    21841 aagtattggt tcttataatg taagaaatct ataagaactc aaagttcccc ccttatattt
    21901 ataaatttaa tttataatat atattctatc atat
//
LOCUS       DAMJYN010000065        21930 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.066, whole genome shotgun sequence.
ACCESSION   DAMJYN010000065 DAMJYN010000000
VERSION     DAMJYN010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21930)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21930)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21930
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.066"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            358..669
                     /gene="rpsJ"
                     /locus_tag="PC466_002640"
     CDS             358..669
                     /gene="rpsJ"
                     /locus_tag="PC466_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HDF2770007.1"
                     /translation="MAKNEKIRIRLKSYDHKLLDFSAGKIVETAKKAGSQVSGPVPLP
                     TEKQVVTILRAVHKYKDSREQFEIRTHKRLIDIANPTPKTVDSLMRLDLPAGVDIEIK
                     L"
     gene            761..1390
                     /gene="rplC"
                     /locus_tag="PC466_002641"
     CDS             761..1390
                     /gene="rplC"
                     /locus_tag="PC466_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HDF2770008.1"
                     /translation="MKGILGKKVGMTQIFTDKGVVIPVTAVEAGPMVVTQIKTVDKDG
                     YNAIQIGFEDAKEKALNKPKKGHLAAANVLKKHLKEFRVDSVEGYTVGQEIKADVFEA
                     GAKIDVTGISKGKGFQGPIKRHGQSRGPETHGSRYHRRPGSMGACSYPGRVFKNKKLA
                     GHMGSVKVTVQNLEVVKVDADKNLILVKGAIPGAKGSVVTIKEAIKVSK"
     gene            1420..2043
                     /gene="rplD"
                     /locus_tag="PC466_002642"
     CDS             1420..2043
                     /gene="rplD"
                     /locus_tag="PC466_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001127258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HDF2770009.1"
                     /translation="MPKLNVLNVSGQNVGEIELSDSIFGVEVNGHVLYEVVKNQLANK
                     RQGTQSAKTRAEVRGGGRKPWKQKGTGRARQGSTRSVQWVGGGVAFAPKPRSYKYTLP
                     KKVRRLAMKSALSSKVQNSEVIVLDALNMDAPKTKEFAQILNNINAAKKALVVIADKN
                     DNVIKSARNIEGVQTALVNTMNVYDILKYDSFIITTDAVKKVEEVYA"
     gene            2043..2333
                     /gene="rplW"
                     /locus_tag="PC466_002643"
     CDS             2043..2333
                     /gene="rplW"
                     /locus_tag="PC466_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HDF2770010.1"
                     /translation="MTNPHDVIIRPVVTEHSMAEMGEKKYTFVVAKDANKTEIKKAVE
                     KVFGVSVDKVNTLNYDGKVKRMGRTQGRTASFKKAVVKLTADSKEIEFFQGM"
     gene            2363..3193
                     /gene="rplB"
                     /locus_tag="PC466_002644"
     CDS             2363..3193
                     /gene="rplB"
                     /locus_tag="PC466_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HDF2770011.1"
                     /translation="MAIKKFRPTSPALRQMTVLVSDEITCNQPEKSLLVNLKKNAGRN
                     VHGRITVRHRGGGQKRKYRIIDFKRDKDGIPAKVATIEYDPNRTANIALLNYADGEKR
                     YILAPVGINVGDTILSGLGADIKPGNCLALKDMPVGTIIHNIELKPGKGAQLVRSAGV
                     SAQLMAKEGKNALLRLPSGEMRLVSINCKATIGQVGNIEHGNVVIGKAGRKRHMGIRP
                     TVRGSVMNPNDHPHGGGEGRSPIGRPSPVTPWGKPALGYKTRKKNKASNKLIVSRRTK
                     "
     gene            3228..3509
                     /gene="rpsS"
                     /locus_tag="PC466_002645"
     CDS             3228..3509
                     /gene="rpsS"
                     /locus_tag="PC466_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003454422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HDF2770012.1"
                     /translation="MSRSTKKGPFVHARLLKKIEAMNASGNKEVIKTWSRSSTVFPQM
                     VENTIAVHDGRKHVPVYITEDMVGHKLGEFVPTRTFKGHKDDEKSNKRK"
     gene            3541..3876
                     /gene="rplV"
                     /locus_tag="PC466_002646"
     CDS             3541..3876
                     /gene="rplV"
                     /locus_tag="PC466_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HDF2770013.1"
                     /translation="MEAKATAKYVRVSPRKAGQICDLVRGKNVDEALAILKFTPRGAA
                     SIIAKVVKSAKANAENNHEMDTEKLYIASIVANQGPTMKRFMPRAMGRATTIRKRTSH
                     IEVVVKEKK"
     gene            3899..4714
                     /gene="rpsC"
                     /locus_tag="PC466_002647"
     CDS             3899..4714
                     /gene="rpsC"
                     /locus_tag="PC466_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HDF2770014.1"
                     /translation="MGQKVNPHGLRVGVIKDWDSRWFATDKKEFGNLLLEDHNIRKFL
                     KKRLYSAGVAKIEIERSANKIKMDLHVAKPGVVIGRAGAGIEALKAELEKMTKKTIIV
                     NIVEVRSTDKNAQLVAENIALAIERRVAFRRAMKQAIQRAMKSGAKGIKVSASGRLGG
                     AEMARTEGYSEGNVPLQTLRADIDYGFAEADTTYGKIGIKVWICNGEVLPTRDGVNPR
                     EESRKSDRRDNKRDNRRNDRRGNDRRGNDNRGNYRGQRPQGGSRPQRTENKGN"
     gene            4750..5181
                     /gene="rplP"
                     /locus_tag="PC466_002648"
     CDS             4750..5181
                     /gene="rplP"
                     /locus_tag="PC466_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HDF2770015.1"
                     /translation="MLMPKRVKRRRVHRGSMAGQAHKGNKVTYGEFGLVALEASWITS
                     NQIEAARIAMTRYIKRGGKVWIKIFPHKPVTRKPAETRMGAGKGSPEYWVAVVKPGRV
                     MFELAGVSEDKAREAMRLAAHKLPIKCKFVKKEDLEVKGGE"
     gene            5183..5386
                     /gene="rpmC"
                     /locus_tag="PC466_002649"
     CDS             5183..5386
                     /gene="rpmC"
                     /locus_tag="PC466_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005810148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HDF2770016.1"
                     /translation="MKAKELRDLTSEELMNKLNDFKSELFSLRFQLATGQLENTARIK
                     FVKKDIAKVKTVLAERKLYETRA"
     gene            5410..5664
                     /gene="rpsQ"
                     /locus_tag="PC466_002650"
     CDS             5410..5664
                     /gene="rpsQ"
                     /locus_tag="PC466_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HDF2770017.1"
                     /translation="MERGRRKVRIGRVVSDKMDKTIVVAVEEFVRHPLYNKRVKRTKK
                     FKAHDEKNICNIGDRVKIMETRPLSKDKRFRLVEVVEKVK"
     gene            5690..6058
                     /gene="rplN"
                     /locus_tag="PC466_002651"
     CDS             5690..6058
                     /gene="rplN"
                     /locus_tag="PC466_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007885948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HDF2770018.1"
                     /translation="MIQQESRLRVADNSGAKELLCIRVLGGSKRRYGNIGDVIVATVK
                     SATPGGVVKKGKVVKAVIVRSKQGVRRNDGSYISFDENAAVIIKDDKTPVGTRIFGPV
                     ARELRDNEFMKIVSLAPEVL"
     gene            6082..6387
                     /gene="rplX"
                     /locus_tag="PC466_002652"
     CDS             6082..6387
                     /gene="rplX"
                     /locus_tag="PC466_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HDF2770019.1"
                     /translation="MRVKKGDTVVVIAGKDKGKKGSVLKVYPKTSKVLVEGVNVITKH
                     QKPSAMNQQGGIINKEAPIHISNVMPFDPETGKGVRVRYEVKDGNKVRVSAKSGKEL"
     gene            6417..6959
                     /gene="rplE"
                     /locus_tag="PC466_002653"
     CDS             6417..6959
                     /gene="rplE"
                     /locus_tag="PC466_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HDF2770020.1"
                     /translation="MASRLQEKYMKEVAPALMEKFGYKNVMEIPKLNKIVINMGIGDA
                     RENPKGLEKGVEELEMISGQKPVITKARKSVANFKLREGMPIGTKVTLRADKMFYFMD
                     KLVSVSLPRVRDFRGVNPNAFDGRGNYALGVKEQLIFPEIEYDKIDKVRGMDIIFVTT
                     AKTDEEARELLKLLGMPFSK"
     gene            6977..7162
                     /locus_tag="PC466_002654"
     CDS             6977..7162
                     /locus_tag="PC466_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HDF2770021.1"
                     /translation="MARKAMVVKQQRKQKYATREYTRCTICGRPHSVLKKFGICRICF
                     RELAYKGQIPGVRKASW"
     gene            7195..7593
                     /gene="rpsH"
                     /locus_tag="PC466_002655"
     CDS             7195..7593
                     /gene="rpsH"
                     /locus_tag="PC466_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012158382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HDF2770022.1"
                     /translation="MTMTDPIADMLTRIRNANVVKHETVDVPASNMKKELARILLEEG
                     FIRGYDVIEDGKQGIIRIQLKYGQEGERVITGLKKISKPGMRVYAANHEIPKVLNGLG
                     ISVISTSKGILTDKQARKENVGGEVICYVW"
     gene            7624..8166
                     /gene="rplF"
                     /locus_tag="PC466_002656"
     CDS             7624..8166
                     /gene="rplF"
                     /locus_tag="PC466_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HDF2770023.1"
                     /translation="MSRIGVKPIIIPAGVEVTIAEGNLVTVKGPKGTLTKQLSAELNI
                     KKEENTIMVERPTDNKKHRSLHGLTRTLLDNMVVGVNTGFEKKLELKGVGYRAQKQGK
                     KLVMNLGFSHPVEMEDPEGITVEAPNQTELIVKGIDKQLVGNYAAKIRAWRKPEPYKG
                     KGIKYVDEVIRRKEGKTGKK"
     gene            8202..8570
                     /gene="rplR"
                     /locus_tag="PC466_002657"
     CDS             8202..8570
                     /gene="rplR"
                     /locus_tag="PC466_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HDF2770024.1"
                     /translation="MLKKADKNANRLQRHKRVRRKISGTSQRPRLCVFRSANNIYAQI
                     IDDTKRVTLVAASSLEAEVKSAVNHTGNKEAAKKVGELVAKKAVEKGITEVVFDRGGY
                     LYHGRIQELAEGAREAGLKF"
     gene            8591..9100
                     /gene="rpsE"
                     /locus_tag="PC466_002658"
     CDS             8591..9100
                     /gene="rpsE"
                     /locus_tag="PC466_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011109776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HDF2770025.1"
                     /translation="MLRRKPIDAGQLDLQEKVVEVRRVTKVVKGGRNFRFAALVVVGD
                     ENGHVGIGAGKAMEVPDAIKKAVEDAKKNLIVVPIVGTTIPHEVRGHFGAGNILIMPA
                     VEGTGVIAGGPARAVLELAGLKDVRAKSLGSNNPRNMVNATIEGLNSLKTVEDIAKLR
                     GKKVEELLG"
     gene            9115..9300
                     /gene="rpmD"
                     /locus_tag="PC466_002659"
     CDS             9115..9300
                     /gene="rpmD"
                     /locus_tag="PC466_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HDF2770026.1"
                     /translation="MAKLQIKLVRSVIGTTPNQKKNVEALGLRKREQVVVKEDNAQTR
                     GMINKVSHLLEVTEIAE"
     gene            9333..9776
                     /gene="rplO"
                     /locus_tag="PC466_002660"
     CDS             9333..9776
                     /gene="rplO"
                     /locus_tag="PC466_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HDF2770027.1"
                     /translation="MKLHELKPAEGAVRAKRRLGRGTATGQGKTAGRGQKGQWSRSGG
                     GVRVGFEGGQMPLARRLPKRGFNNIFKKVYTEVNVEVLNRFENGTEITAELLKSTKTI
                     SKIGKDGIKILGEGNLEKALTVKAAKFTASAQEKIEKAGGKAELV"
     gene            9820..11088
                     /gene="secY"
                     /locus_tag="PC466_002661"
     CDS             9820..11088
                     /gene="secY"
                     /locus_tag="PC466_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HDF2770028.1"
                     /translation="MLSKLKQAWKIKAVRKKVMYTLMMIVIFRIGTTIPVPGIDTSII
                     QKMVGGNSLLSLYNMFTGGAFSNFSLFALGISPYITASIIIQLLTVGFESLAELQKSG
                     EEGKKKINKYTKYTALALAVVQALGITLGIVRSALISNSVFFITTVVITLVSASMLVM
                     WIGDKITEKGIGNGSSVIIFAGIISRIPTDVIKISQQVKSGEVAPWVIVILAVVILLT
                     VTGVTFIQEATRKIPVQYAKRVVGRKMYGGQSSHIPMKVNQSGVMPIIFASSLLAFPQ
                     TIAMFMGPNAQAFVQKYLSMATEQGFWTYRSIEILLIIFFSYFYTTVSFNTEDISKNM
                     KNNGGFIPGIRPGEPTMDYLNRILTRLTLAGATFLAIIAMVPALTTHYMKVNMSLAGT
                     SLLIVVGVALELKRQLESNLVMRSYQGFLK"
     gene            11105..11755
                     /locus_tag="PC466_002662"
     CDS             11105..11755
                     /locus_tag="PC466_002662"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HDF2770029.1"
                     /translation="MRIILLGPPGAGKGTQAAGIVEKYNIPHISTGDIFRKNIKEGTE
                     LGKKAKEYMDQGLLVPDELTVGLVTDRISQEDCKNGFMLDGFPRNVAQGEHLDIFLKN
                     AGISLDKVVNIEVDKSILVSRAVGRRICKSCGATYHVEFNPPKVEGVCDVCQGELYQR
                     ADDNEETVSKRIQVYLDETKPLVDYYSKQGIIADIKGDQAIDKVFEDIVAALGSGK"
     gene            11756..12502
                     /gene="map"
                     /locus_tag="PC466_002663"
     CDS             11756..12502
                     /gene="map"
                     /locus_tag="PC466_002663"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HDF2770030.1"
                     /translation="MIILKSKKEIELLREAGKIVADTHEVLRKAISPGISTLELDKIA
                     EENIRKYNAEPSFKGYGGFPGSICASINREVVHGIPGETILQEGDIVSLDIGAYYKGY
                     HGDSAKTHGVGMISEEDRKLIEVTRESFYEGIKFAKLGYRLSDISHAVQTHVEKHGFS
                     VVRDLVGHGVGANLHEDPQVPNYGLPGKGPRLREGMVIAIEPMVNAGRYHVKTLSDGW
                     TTVTIDGKKSAHYEHTIAITEHEPLILTKL"
     gene            12524..12793
                     /locus_tag="PC466_002664"
     CDS             12524..12793
                     /locus_tag="PC466_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KOW domain-containing protein"
                     /protein_id="HDF2770031.1"
                     /translation="MLSDNLSIGQVVKVSLGRDKGNLFFVVKIINNEYVLIADGKKRK
                     LDKPKLKKVKHLKKYDFINDEVRKRVVSGQEITDSFLRAELTKLN"
     gene            12831..13049
                     /gene="infA"
                     /locus_tag="PC466_002665"
     CDS             12831..13049
                     /gene="infA"
                     /locus_tag="PC466_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001029884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HDF2770032.1"
                     /translation="MAKKDVIELEGTVSEALPNAMFKVKLENGHEILCHISGKLRMNF
                     IRILEGDKVNVELSPYDLTRGRITWRKK"
     gene            13085..13198
                     /gene="rpmJ"
                     /locus_tag="PC466_002666"
     CDS             13085..13198
                     /gene="rpmJ"
                     /locus_tag="PC466_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HDF2770033.1"
                     /translation="MKVRPSVKPICEKCKVIKRKGKVMVICENPKHKQKQG"
     gene            13351..13722
                     /gene="rpsM"
                     /locus_tag="PC466_002667"
     CDS             13351..13722
                     /gene="rpsM"
                     /locus_tag="PC466_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005810116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HDF2770034.1"
                     /translation="MARIAGVDLPREKRAEIGLTYIYGIGKATANEILAKAEINPDTR
                     IKDLSEDQVNELRKVIDDDFLVEGDLRREIALNIKRLRDIKCYRGIRHAKGLPLRGQR
                     TKTNARTRKGPRKTVSRKKKK"
     gene            13758..14156
                     /gene="rpsK"
                     /locus_tag="PC466_002668"
     CDS             13758..14156
                     /gene="rpsK"
                     /locus_tag="PC466_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006440523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HDF2770035.1"
                     /translation="MAKPKKKVTRIRRRERKNIERGHAHIQSTFNNTIITLTDVHGNA
                     ISWASSGQLGFKGSRKSTPFASQMAAETAAKAAMEHGLKSVEVFVKGPGSGREAAIRA
                     LQATGLEVTMIKDVTPIPHNGCRPPKRRRV"
     gene            14188..14811
                     /gene="rpsD"
                     /locus_tag="PC466_002669"
     CDS             14188..14811
                     /gene="rpsD"
                     /locus_tag="PC466_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HDF2770036.1"
                     /translation="MARYTGASCRQCRREGMKLFLKGDRCYTDKCAIVKRNYAPGQHG
                     QGRKKVSNYGLQLREKQKVKRIYGVLETQFRNLYERAENMPGKAGENLLSLLERRLDN
                     VVYRMGLASSRKEARQLVTHGHFTLNGNKVDIPSLIVKVGDVIEVKEKSRSSAKFKNL
                     VEVNSRIAPKWLEANVEGMTAKVVGVPTREDIDLEIAEHLIIELYSK"
     gene            14889..15836
                     /locus_tag="PC466_002670"
     CDS             14889..15836
                     /locus_tag="PC466_002670"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HDF2770037.1"
                     /translation="MIEIEKPKVDIVELSEDYRYGKFVIEPLERGYGITIGNALRRIL
                     LSSLPGVAVNAIKIDGVLHEFSTIPGVKEDVTEIILTLKELSATIDGEGSRTLKIEAQ
                     GPCSITGADIICPPDVEILSKDLAIATLDDNAKLNMEIFVDKGRGYVSAEENKTENVP
                     IGVLPVDSIYTPVEKVSYHVENTRVGQKTDYDKLVLEVWTNGSINPQEGISLAAKVLV
                     EHLNLFIDLTEHVSSVEIMVEKEEDQKEKVLEMTIEELDLSVRSYNCLKRAGINTVEE
                     LANKSEDDMMKVRNLGKKSLEEVIQKLEELGLGLKPSEE"
     gene            15857..16198
                     /gene="rplQ"
                     /locus_tag="PC466_002671"
     CDS             15857..16198
                     /gene="rplQ"
                     /locus_tag="PC466_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003357477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HDF2770038.1"
                     /translation="MAKYRKLGRETAHRNLMLRNLVTCLLRSGRIETTVTRAKETRRM
                     AEKMITLAKRGDLHARRQVLAYVMDETVVNNLFTDLAPKYAERNGGYTRIIKIGPRKG
                     DAAEMAFIELV"
     gene            16318..17151
                     /locus_tag="PC466_002672"
     CDS             16318..17151
                     /locus_tag="PC466_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HDF2770039.1"
                     /translation="MDNIVKVNNISFEYITDEAKLKAIDNLSLDVKKGEFVAIIGHNG
                     SGKSTLSKNLNAILMPTEGNILIDDMDTKEEERLWDIRQTAGMVFQNPDNQIVATIVE
                     EDVAFGPENLGIEPKEIRRIVEESLKSVGMYDLRDRQPHLLSGGQKQRVAIAGIIAMR
                     PKCIIFDEATAMLDPSGRKEVMKTIKRLNKEENITVIHITHFMEEAVEADRVVVMEKG
                     KKILEGTPREVFSKIKMLKEIGLDVPCMTELSSLLIEEGINISSDILTVDEMVMELCQ
                     L"
     gene            17139..18005
                     /locus_tag="PC466_002673"
     CDS             17139..18005
                     /locus_tag="PC466_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HDF2770040.1"
                     /translation="MSIIVKNLTHIYNEGMPFASKALDDISFEIKDRDFVGLIGHTGS
                     GKSTLIQHLNGLLKPSSGEIFINDFNITDKNLNLTEIRKRVGVVFQYPEYQLFEETID
                     KDIAFGPSNLGLEESEIHNRVKASMEAVGLDYEGFKDKSPFELSGGQKRRVAIAGVIA
                     MNPEVLILDEPTAGLDPGGRDEIFNLIKDLHEKKNMTIILSSHSMDDMAKLAKTLIVM
                     NHGSVEFMGTPREVFKSNASKLKDIGLDIPQVLELALKLREKGFDISEDILTLEEAKQ
                     EILKVVRGRGLC"
     gene            17999..18802
                     /locus_tag="PC466_002674"
     CDS             17999..18802
                     /locus_tag="PC466_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HDF2770041.1"
                     /translation="MLKDITIGQYYPTSSAIHKLDPRIKLVATIVFMVSIFVVNKFWP
                     YIVVLLCLLAMIKLANIPVKYIVKGVKPLKWIILFTFLINIFFLPGDEIWSFGFLAIT
                     KQGLRQAIFMAIRLIFLVVGTSLLTLTTSPIELTDGIERLLNPFKKIGLPVHELAMMM
                     TIALRFIPTLLDETDKIMKAQMSRGADFESKNLINRAKNLVPLLVPLFVSAFRRADEL
                     AMAMEARCYRGGHNRTKMRESVISRRDYMACVFQVVYLGAIIATRFIAI"
     gene            18834..19565
                     /gene="truA"
                     /locus_tag="PC466_002675"
     CDS             18834..19565
                     /gene="truA"
                     /locus_tag="PC466_002675"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003514691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HDF2770042.1"
                     /translation="MRNIKIKIQYNGKNYCGWQKQPDSLGIQGTIERAIYDITKEETS
                     LIGSGRTDSGVHAIGQIANFKINSGISIESIPMALNAKLPKDISVIEACEVNDDFHSR
                     YSAKGKTYKYLVYNSKFRNPILSEISYQVKYELDFDKMCSEAKSLLGTHDFKGFMSSG
                     SSVKDTVRTIYDIDISKKDDLITFEISGNGFLYNMVRIIVGTLVDMGRGRINEPFLDI
                     IQSKTRSRCGHTAPAQGLFLKKVHY"
     gene            19685..20116
                     /gene="rplM"
                     /locus_tag="PC466_002676"
     CDS             19685..20116
                     /gene="rplM"
                     /locus_tag="PC466_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HDF2770043.1"
                     /translation="MKSYIAKPADVQRKWYLVDAEGKTLGRLATEIATVLRGKHKPTF
                     TPHVDGGDFVVVVNAEKIVLSGKKLDQKYYRYHTGYVGGLKEISYRDMMDKKPEEVIS
                     HAVSGMLPKNKLRSRMMTRLRVFAGAEHTHAAQNPEVLNFK"
     gene            20145..20537
                     /gene="rpsI"
                     /locus_tag="PC466_002677"
     CDS             20145..20537
                     /gene="rpsI"
                     /locus_tag="PC466_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003515879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HDF2770044.1"
                     /translation="MANVQYYGTGRRKSSVARVRLVAGEGNILVNGRALENYFNYETL
                     IRDVKQPLVLTGNENKYDVIVKVEGGGFTGQAGAIRHGISRALLKADLDLRPALKKEG
                     FLTRDARMKERKKYGLKAARRAPQFSKR"
     gene            20996..21748
                     /gene="cwlD"
                     /locus_tag="PC466_002678"
     CDS             20996..21748
                     /gene="cwlD"
                     /locus_tag="PC466_002678"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase CwlD"
                     /protein_id="HDF2770045.1"
                     /translation="MEYYSVFISIHIQGDVVRKYIKHIIFSFAMICLVVVSIFEIKNI
                     SEDVIKYMPVTNKTIILDAGHGGIDPGALNKDKSTSEKDINLAITLKLRELIESSGGL
                     VILTREDDSSLYKEENNKTTRQKYNENLKNRKEIISNSNANMFVSIHLNAFEQSKYYG
                     AQTFYPKDKQDSKELSKCIQEELKRVVDKTNNREVKPRDDIYLLKENNIPSVLIECGF
                     LSNEKECKLLTDETYQEKIAWAIYIGIQKYLS"
BASE COUNT         8807 a         2558 c         4501 g         6064 t
ORIGIN      
        1 atggatttaa tataaaaaaa agaggggggt aactcctctc ttttttgttt tttgttgaca
       61 agtagcgcta aagcatatat actaaactag tgccttgaga cagattaaca atcaagttta
      121 aggttatgat gttgtaatag aaaataaaat tgaaaaaaac agaaaaaaaa cttgaaaaaa
      181 tgtaacagat gatataaaat ataatagtgt gcttgagaga ttaagaaaat aataattaaa
      241 tcctagtgaa atacgaactg atatcgattt aaaagttaca acacacccgg agcagtgtat
      301 cggtattggt tgtacgcaac ttgaaaatta aacacgtgat aaaggaggga aaacaaaatg
      361 gctaagaatg aaaaaataag aataagatta aaatcatatg atcacaaatt attagatttt
      421 tcagcaggta aaatagttga aactgctaaa aaggctggat cacaagtttc aggacctgtg
      481 cctctaccaa cagaaaaaca agttgtaact atattaagag ctgtacataa gtacaaagac
      541 tctagagaac aatttgaaat aagaactcat aaaagactaa tcgacatagc taatccaaca
      601 cctaagacag ttgactcatt aatgagatta gacttaccag caggtgtaga tatagaaata
      661 aaattataag aacccctaag atattatcct atagatgatt atcttagaat gattactcta
      721 aaagatgtaa tccgctgtaa gaattatagg aggtgctaat atgaaaggaa tattaggcaa
      781 aaaagttggt atgactcaaa tattcactga taaaggtgta gttatacctg taacagctgt
      841 tgaagcaggg cctatggtcg ttactcaaat aaaaacagtt gataaagatg gatacaatgc
      901 tatacaaata ggttttgaag atgctaaaga aaaagcttta aacaaaccta aaaaaggaca
      961 tttagctgct gctaatgttt taaagaaaca tttaaaagaa tttagagtag attctgtaga
     1021 aggatacaca gtaggacaag aaataaaagc tgatgtattt gaagcaggtg caaaaataga
     1081 tgttactgga ataagtaaag gtaagggatt ccaaggtcca ataaaaagac atggacaaag
     1141 tagaggtcct gaaactcatg gttctagata ccacagaaga ccaggttcaa tgggagcttg
     1201 ttcttaccca ggtagagtat ttaaaaacaa aaaattagct ggacatatgg gaagcgtaaa
     1261 ggtaacagtt caaaacttag aggttgttaa agtagatgct gacaagaacc ttatattagt
     1321 taaaggagct ataccaggag ctaaaggttc agtagtaact ataaaagaag ctataaaggt
     1381 ttctaaataa tgactaacct agagaaagga ggaataacaa tgccaaaatt aaatgtacta
     1441 aatgttagtg gacaaaacgt tggagaaata gaattatcag attctatatt tggcgtagaa
     1501 gttaatggac atgttttata cgaagttgta aaaaatcaat tagcaaataa gagacaagga
     1561 actcaatctg ctaaaactag agcagaagtt agaggtggcg gaagaaaacc ttggaaacaa
     1621 aaaggaacag gtagagcaag acaaggttct acaagatctg tacaatgggt aggtggagga
     1681 gttgcttttg cacctaaacc aagaagctac aaatatacat tacctaagaa ggtaagaaga
     1741 ttagctatga agagtgcttt atcttcaaaa gttcaaaata gtgaagttat agtattagat
     1801 gcattaaaca tggatgctcc taagactaaa gaatttgctc aaatattaaa caatataaat
     1861 gctgctaaaa aagctttagt agttatagct gacaaaaacg ataacgtaat aaaatcagct
     1921 agaaatatag aaggtgttca aactgcatta gttaatacta tgaatgtata tgatatatta
     1981 aaatacgatt catttataat aactacagat gctgttaaaa aagtggagga ggtgtacgca
     2041 taatgactaa tccacatgat gtaataataa gaccagttgt aactgagcac agtatggctg
     2101 aaatgggtga aaaaaaatac acttttgttg tggctaaaga tgcgaacaaa actgaaataa
     2161 aaaaagcagt agaaaaagta ttcggagtta gtgttgataa agtaaatact ttaaactacg
     2221 atggaaaagt taaaagaatg ggtagaactc aaggaagaac agcaagcttt aagaaagcag
     2281 tagttaaatt aactgctgat agtaaagaaa tagaattctt ccaaggaatg tagtattata
     2341 acaaacgaag gagggaaaac agatggctat aaaaaagttt agaccaactt ctcctgcctt
     2401 aagacaaatg acagttttag tttctgatga aataacatgt aatcaaccag aaaaatctct
     2461 tttagttaac ttaaagaaaa atgctggtag aaacgtacat ggtagaataa ctgttcgtca
     2521 tagaggtgga ggacaaaaaa gaaaatatag aataatagat tttaaaagag ataaagatgg
     2581 tatacctgct aaggttgcta ctatagaata tgatccaaac agaactgcaa atatcgcatt
     2641 attaaactat gctgatggag aaaaaagata tatattagct ccagttggaa ttaacgttgg
     2701 agatactata ttatcaggat taggtgctga tataaaacca ggaaactgtt tagcattaaa
     2761 agatatgcca gttggtacta tcattcataa tatagaatta aagccaggaa aaggagctca
     2821 attagttaga tctgctggag tttctgcaca attaatggct aaagaaggaa aaaatgcttt
     2881 attaagatta ccatcaggtg agatgagatt agtaagcata aactgtaaag ctactatagg
     2941 tcaagttgga aatatagagc atggtaacgt agttatcggt aaagcaggta gaaaaagaca
     3001 tatgggaata agacctactg taagaggttc tgtaatgaac cctaatgacc atccacacgg
     3061 tggaggggaa ggtagatctc caataggtag accatctcct gttactccat ggggtaaacc
     3121 agctcttgga tacaaaacta gaaagaaaaa taaagcttca aataaactaa tagtatcaag
     3181 aagaactaag tagtaaattt atttttgctc ggaaaggagg aatataaatg tcaagatcaa
     3241 ctaaaaaagg gccttttgtc catgcaagac ttttaaagaa gatagaagct atgaatgcta
     3301 gtggaaataa agaagttata aaaacttggt caagatcttc aactgtattt ccacaaatgg
     3361 tagaaaacac tatagctgtt catgatggaa gaaaacatgt tccagtatat ataacagaag
     3421 atatggttgg acataaatta ggtgagttcg ttcctactag aactttcaaa ggacataagg
     3481 atgacgaaaa atctaataag agaaaataat taaattatga ctaagaaagg aggaataaca
     3541 atggaagcaa aagctactgc taaatacgta cgtgtatcac caagaaaagc aggccaaata
     3601 tgtgaccttg ttagaggaaa gaatgttgat gaagcattag caatattaaa gtttactcca
     3661 agaggagcag cttcaataat agctaaggtt gtaaaatcag ctaaagctaa cgcagaaaac
     3721 aatcacgaaa tggatactga aaaattatat atagcatcaa tagttgctaa tcaaggacca
     3781 acaatgaaga gattcatgcc tagagctatg ggtcgtgcaa ctacaataag aaaaagaact
     3841 tctcatatag aggttgttgt taaagaaaaa aaataattaa tagataggag ggaaagtaat
     3901 gggtcaaaag gttaatccac acggcttaag ggtcggtgtt ataaaagatt gggactcaag
     3961 atggttcgct actgataaaa aagagttcgg aaacttatta ttagaagacc ataatatacg
     4021 taaattctta aagaaaagat tatactcagc tggagttgct aagatagaaa tagaaagatc
     4081 agctaacaaa ataaaaatgg acttacacgt tgctaagcct ggtgtagtta taggaagagc
     4141 tggtgcagga atcgaagcat taaaagctga attagaaaaa atgacaaaga aaactataat
     4201 agttaatata gtagaagtaa gaagtacaga taaaaatgct caattagtag ctgaaaatat
     4261 agctttagct atagagagaa gggttgcttt cagaagagca atgaaacaag ctatacaaag
     4321 agcaatgaaa tctggtgcta aagggataaa agtttctgct tcaggaagat taggtggagc
     4381 tgaaatggct agaactgaag gttatagtga aggaaatgtg ccactacaaa ctttaagagc
     4441 agatatagat tatggtttcg ctgaagctga tacaacttat ggaaaaatcg gtataaaagt
     4501 ttggatatgt aatggtgaag ttttaccaac tagagacggt gtaaatccaa gagaagaaag
     4561 cagaaagagc gatagaagag acaacaagag agataataga agaaacgata gaagaggaaa
     4621 tgacagaaga ggaaatgata acagaggaaa ctacagagga caaagacctc aaggtggatc
     4681 aagacctcaa agaactgaaa acaaaggaaa ttaataatag ttaggttcaa ggaaggagga
     4741 aaaatactca tgttaatgcc aaaaagagta aagcgtcgta gagttcatag aggaagcatg
     4801 gctgggcaag ctcataaggg taataaagtt acttatggtg agtttggatt agtagcatta
     4861 gaagcttctt ggataacttc taatcaaata gaagctgcca gaatcgcgat gactagatat
     4921 ataaaaagag ggggaaaggt ttggataaaa atattccctc ataaaccagt aacaagaaaa
     4981 ccagcagaga ctcgtatggg tgcagggaaa ggttctccag aatattgggt agctgtagtt
     5041 aagccaggaa gagttatgtt tgaattagca ggtgtttctg aagataaagc aagagaagct
     5101 atgagacttg ctgcacataa attaccaatc aaatgtaaat ttgttaaaaa agaagattta
     5161 gaagtaaagg gtggtgaata ggatgaaagc taaagaatta agagatttaa caagcgaaga
     5221 gctaatgaac aaattaaacg acttcaaaag tgaattattt agcttaagat tccaattagc
     5281 tactggtcaa ttagaaaata cagctagaat aaagtttgtt aagaaggata tagcaaaagt
     5341 taaaactgtt cttgctgaaa gaaagttata cgaaactaga gcttaatttg gaaaggaggc
     5401 tttttaaaca tggaaagagg aagaagaaaa gttagaatag gccgtgttgt tagtgataag
     5461 atggataaaa caatagtagt agctgttgaa gaattcgtac gtcatccact atataataaa
     5521 cgtgttaaga gaactaagaa attcaaggct catgatgaaa agaatatatg taacatcgga
     5581 gatagagtta aaataatgga aactagacca ttatctaaag ataagagatt cagactagtt
     5641 gaagttgttg agaaagttaa gtagtttttg aagaaggagg gattacgata tgatacaaca
     5701 agaatcacgt ctaagagttg ctgataactc aggagctaaa gaacttttat gtatacgtgt
     5761 tctaggcgga agtaaaagaa gatatggtaa cataggcgac gttatagttg ctactgttaa
     5821 aagtgcaaca cctggtggag ttgtaaaaaa aggtaaggtt gttaaagctg ttatagtaag
     5881 aagcaaacaa ggcgtaagac gtaatgacgg aagctatata tcttttgatg aaaatgctgc
     5941 tgttataata aaggacgata aaactccagt aggaactcgt atattcgggc ctgttgctag
     6001 agagttaaga gacaatgaat tcatgaaaat agtttctctt gctccagaag tactataatt
     6061 aaggaggtgc aataggacat gatgcgtgtt aaaaaaggtg acactgttgt agttatagca
     6121 ggtaaagata aaggtaaaaa aggttcagtt ttaaaggtat atcctaaaac tagcaaagtg
     6181 ttagttgaag gtgtaaatgt aataactaaa catcaaaaac caagtgctat gaaccaacaa
     6241 ggtggaataa taaataaaga agccccaata cacatatcta atgtaatgcc atttgatcct
     6301 gaaacaggaa aaggcgttag agtaagatat gaagtaaaag atgggaacaa agtaagagta
     6361 tcagcaaaga gcggaaaaga attataataa atattgcttg aaaggaggga ccttaaatgg
     6421 cttctagatt acaagaaaaa tacatgaaag aagttgctcc tgctttaatg gagaaatttg
     6481 gatacaaaaa cgtaatggag atacctaagt taaataaaat agttattaac atgggtatag
     6541 gtgacgctag agaaaatcca aaaggattag aaaaaggcgt tgaagaatta gaaatgatat
     6601 caggacaaaa gcctgttata actaaagcta gaaaatctgt tgctaacttc aaattaagag
     6661 aaggaatgcc aataggaaca aaagttacat taagagctga caaaatgttc tactttatgg
     6721 acaaattagt ttcagtttct ttaccaagag ttagagattt tagaggagtt aaccctaatg
     6781 cttttgatgg tagaggaaat tatgctttag gagttaaaga acaattaata ttccctgaaa
     6841 tagaatatga taaaatagat aaagtaagag gaatggatat aatatttgtt actacagcaa
     6901 aaactgacga agaagctcgt gaattattaa aattattagg aatgccattt tctaagtaag
     6961 caaaggaggg attcccgtgg ctagaaaagc gatggttgtt aagcaacaaa gaaagcaaaa
     7021 gtacgctact agagaataca ctagatgtac tatatgcgga agaccgcatt cagttttgaa
     7081 aaaatttggt atatgccgta tatgctttag agaattagct tataaaggtc aaatacctgg
     7141 tgttagaaaa gcaagctggt agaagcttga ttagaatgga aggagggcaa caaaatgaca
     7201 atgacagatc caattgcaga tatgcttact cgtataagaa atgctaatgt tgttaagcat
     7261 gaaactgtag atgttccagc ttctaatatg aagaaagaat tagctagaat cttattagaa
     7321 gaaggtttca taagaggtta tgatgttata gaagatggaa aacaaggtat cataagaata
     7381 caattaaagt acggacaaga aggcgaaaga gttataacag gtcttaagaa aatatctaag
     7441 cctggaatga gagtttacgc tgctaaccat gagataccaa aagtattaaa cggattagga
     7501 atatcagtta tatctacttc aaaaggaata ttaactgaca agcaagctag aaaagaaaat
     7561 gttggtggag aagtaatctg ctacgtttgg taattaatat gaacaatgta aggaggtgcg
     7621 accatgtcaa gaataggtgt taagccaata ataataccag caggtgttga agttactata
     7681 gctgaaggaa atttagttac agtaaaaggt ccaaaaggaa ctttaactaa acaattaagt
     7741 gctgagttaa acataaaaaa agaagaaaat acaataatgg ttgaaagacc aactgataat
     7801 aaaaaacata gatctttaca cggactaact agaactttat tagataatat ggttgtaggt
     7861 gtaaatactg gtttcgaaaa gaaattagaa ttaaaaggtg ttggatatag agctcaaaaa
     7921 caaggaaaga aattagttat gaacttaggt ttctctcatc cagttgagat ggaagatcca
     7981 gaaggaataa ctgttgaagc tccaaaccaa acagagttaa tagtaaaagg tatagacaag
     8041 caattagtag ggaattatgc tgctaagata agagcttgga gaaagccaga gccatacaaa
     8101 ggtaaaggta taaaatacgt tgatgaagta atcagacgta aagaaggaaa aactggtaaa
     8161 aaataatacc aaaacttaaa cgctagaaag gagtgagcta ggtgttaaaa aaggctgata
     8221 aaaatgctaa tagacttcaa agacataaga gagttcgtag aaaaataagc ggtacttctc
     8281 aaagaccaag attatgtgta tttagaagtg ctaacaatat atatgctcaa ataatagatg
     8341 acacaaaaag agtaactcta gttgctgcat cttctttaga agcagaagtt aagagtgctg
     8401 tcaatcatac aggaaacaag gaagcagcta agaaagttgg agaattagtt gctaaaaaag
     8461 ctgttgaaaa aggaatcact gaagttgtat ttgacagagg tggatactta tatcatggaa
     8521 gaattcaaga attagctgaa ggtgctagag aagctggtct taagttctaa tacgaaggag
     8581 ggaaaaatac atgctacgtc gtaagccgat agatgcagga caacttgact tacaagaaaa
     8641 agttgttgaa gtaagacgtg ttactaaggt tgtaaaaggt ggtagaaatt tcagatttgc
     8701 agcattagta gttgttggag atgaaaacgg acacgttggt ataggtgctg ggaaagcaat
     8761 ggaagtacca gacgctataa aaaaagcagt tgaagatgct aagaaaaatc taatagtagt
     8821 gccaatagtt gggactacaa ttcctcacga agtacgcgga cactttggtg ctggaaatat
     8881 attaataatg cctgctgtag aaggtacagg agtaatagct gggggacctg ctagagccgt
     8941 acttgagcta gctggactaa aagacgttag agctaaatct ttagggtcta acaatccaag
     9001 aaatatggta aatgctacaa tagaaggact taattctcta aaaacagttg aagatatagc
     9061 taaacttaga ggtaaaaaag ttgaagaact tctagggtaa ggaggtagtg taaaatggct
     9121 aaattacaaa taaagttagt tagaagtgtt ataggaacta ctcctaacca aaaaaagaat
     9181 gttgaagcgt taggattaag aaaaagagaa caagttgttg taaaagaaga caatgctcaa
     9241 acaagaggta tgataaataa agtaagtcac ttattagaag taactgaaat agctgaataa
     9301 tttttataaa gtagtgcaag gaggtgcaat ccatgaagtt acatgagtta aaacctgctg
     9361 aaggtgcagt aagagctaag agaagattag gtagaggtac tgcaactgga caaggtaaaa
     9421 ctgcaggacg tggacaaaaa ggtcaatggt ctcgttctgg tggtggagta agagtaggat
     9481 ttgaaggtgg acaaatgcca ctagctagaa gacttcctaa gagaggtttc aataacatat
     9541 ttaagaaagt ttacacagaa gttaatgttg aagttttaaa cagatttgaa aatggaacag
     9601 aaataactgc agaattatta aaatctacta aaactataag caaaataggt aaagacggaa
     9661 ttaaaatctt aggtgaaggt aatttagaga aagctttaac tgttaaagct gctaaattta
     9721 cagcttcagc tcaagaaaaa atagaaaaag ctggtggaaa agcagagtta gtataataac
     9781 ctgctaatct cctagccagt acaggcgggg tgaattagcg tgctgtcaaa attaaaacaa
     9841 gcttggaaga ttaaagcagt aagaaaaaaa gtaatgtata cacttatgat gatcgtgata
     9901 ttcagaatag gtactactat accagttcca ggcatagaca ctagtattat acaaaagatg
     9961 gtaggcggca atagtctact ttctctgtat aatatgttta ctggtggagc atttagtaac
    10021 ttttcactat ttgctttagg tataagtcca tatatcactg catcaatcat aatacaactt
    10081 ctaacagtag gttttgaaag tttagcagaa cttcaaaaat ctggtgaaga aggaaagaaa
    10141 aaaatcaata agtacactaa atatacagca ctagctctag cagttgtaca agctttggga
    10201 attacattag gaattgtaag aagtgcttta atatcaaata gtgtgttttt tatcacaact
    10261 gttgtaataa cattagtttc agcaagtatg ttagtaatgt ggattgggga caaaattact
    10321 gaaaaaggaa tcggtaatgg tagttcagta ataatatttg caggtataat atcaagaata
    10381 cctacagatg ttattaaaat atcgcaacaa gttaaatctg gcgaagttgc accttgggtt
    10441 atagtgattc tagctgtagt tatattactt acagtaacag gagttacatt tatacaagaa
    10501 gcaactagaa agatacctgt acaatatgct aaaagagttg ttggaagaaa aatgtatgga
    10561 ggacaaagtt ctcatatacc aatgaaagtt aaccagtcag gagttatgcc tataattttt
    10621 gctagttcac ttttagcttt ccctcaaaca atagctatgt ttatgggtcc aaatgctcag
    10681 gcttttgttc aaaaatactt aagtatggca acagaacaag gattttggac atatagatca
    10741 attgagattc tacttataat tttcttctca tatttttata caactgtatc atttaataca
    10801 gaagacatat ctaaaaatat gaaaaataat ggtggattta taccaggtat aagaccaggt
    10861 gagcctacta tggattattt aaatagaatt ttaactagat taactttagc tggagctact
    10921 ttcttagcaa taattgctat ggtgccagct cttacaacac attatatgaa agtaaatatg
    10981 agtctagctg ggacttcatt gctaatcgtt gttggagttg ctttggagct taagagacag
    11041 ttagagtcaa acttagttat gagaagctat caaggtttct taaaataaaa tggagatgga
    11101 taatatgaga ataatattac ttggacctcc aggtgctggt aaaggtactc aggcggcagg
    11161 aatagtagaa aaatacaata tacctcatat atcaacagga gatatattca gaaagaatat
    11221 aaaagaggga acagaacttg gaaaaaaagc taaagaatac atggaccaag gtttattagt
    11281 accagatgag ttaactgtag gtttagttac tgatagaata tctcaagaag attgtaaaaa
    11341 tggatttatg ttagatggat ttccaagaaa tgtagcacaa ggagaacatt tagatatctt
    11401 cttaaaaaat gctggtatat cactagataa agttgtcaat attgaagttg ataagagtat
    11461 attagtgtct agagcagttg gtagaagaat atgtaagtct tgtggagcta cttaccatgt
    11521 tgagtttaat cctcctaaag tagaaggtgt atgtgatgta tgccaaggag aattatatca
    11581 aagagctgat gataatgaag aaactgtatc taagagaata caagtttatc tagatgaaac
    11641 taagccttta gtagattatt atagcaaaca aggtataata gcagatataa aaggtgatca
    11701 agcaatagat aaagtatttg aagatattgt cgcagcctta ggaagtggaa aataaatgat
    11761 tatcttgaaa tcaaaaaaag aaatagaact tttaagagaa gcaggtaaaa tagttgctga
    11821 cactcatgaa gttttaagaa aagctatttc tccgggaata tctactttag aattagataa
    11881 aatagctgaa gagaatataa gaaaatacaa tgcagagcct tcttttaaag gatatggagg
    11941 ttttccagga agtatatgtg cttctatcaa tagagaggta gtacatggta ttccaggaga
    12001 aactatatta caagaaggtg acattgtaag tttggatata ggagcctatt ataaaggata
    12061 tcatggtgat tctgcgaaaa ctcacggagt aggcatgata tctgaagaag ataggaaatt
    12121 gatagaagta actagagaaa gcttctatga aggaataaaa tttgctaaat taggatatag
    12181 actttcagat atctcacacg cagtacaaac acacgttgag aaacatggtt tctcggtagt
    12241 tagagattta gtgggtcatg gagttggagc aaatcttcat gaagacccac aagtacctaa
    12301 ttatggactc ccaggaaaag gaccaagact tagagaagga atggttattg ctatagagcc
    12361 aatggttaat gcaggtcgtt atcatgtaaa gactctatca gatgggtgga cgactgttac
    12421 aatagatgga aaaaaatcag ctcattatga gcatacgata gcaattactg aacatgaacc
    12481 tttgatattg acaaagttgt aatttaaaaa gtaggtgaaa aaagtgctat cagataattt
    12541 aagtataggt caagttgtta aagtttcatt aggacgagat aaaggaaatt tattctttgt
    12601 agtcaaaata attaataatg aatatgtatt aatagctgat ggaaaaaaga gaaaacttga
    12661 caaacctaag ttaaagaaag tgaagcactt aaaaaaatat gattttatta atgatgaagt
    12721 tagaaaaaga gtagtatctg gacaagagat tacagattct tttttaagag ctgaacttac
    12781 taagttaaat tagataattt aacttattga aatggagggc tggttagtta atggccaaaa
    12841 aagatgttat agaattagaa ggtacagttt cagaagcttt acctaatgct atgttcaaag
    12901 ttaaactaga aaatggacat gagatattat gccacatttc tggaaagcta agaatgaact
    12961 tcataagaat tcttgaaggt gacaaggtga atgttgaact ttctccatat gaccttacaa
    13021 gaggaagaat tacttggcgt aagaagtaga ctatattaat atttagtcta aggagggatt
    13081 aataatgaag gttagaccat cagtaaaacc aatatgtgaa aaatgtaaag taataaaaag
    13141 aaaaggaaaa gtaatggtta tctgtgaaaa tccaaagcat aagcaaaagc aaggataaga
    13201 aattattact agcattttgt taaattttat agtataatac tatattgtga tgttaacaaa
    13261 agaacgttaa aatcgttgaa caatctggcg taggattggc atatgatgtg aagttttaaa
    13321 cactaaaaac tatgtgtagg aggtgcgatc atggcaagaa tagctggggt agatttacct
    13381 agagaaaaaa gagcggagat aggcttaact tatatatatg gtataggtaa agcaactgct
    13441 aacgaaatat tagctaaggc tgagataaat ccagatacta gaataaaaga tttatcagaa
    13501 gatcaagtta atgagttaag aaaagttata gatgacgatt tcttagttga aggtgactta
    13561 agaagagaaa ttgctttaaa cataaagaga ttaagagata taaaatgtta tagaggaata
    13621 agacacgcta aaggtcttcc attaagagga caaagaacta agactaatgc tagaactaga
    13681 aaaggtccta gaaaaacagt atctcgtaaa aagaaaaaat aaataaataa taactagatg
    13741 aaggagggaa aaggaaaatg gctaaaccaa aaaagaaagt tacacgtatt agaagaagag
    13801 aacgtaaaaa tatagaacgt ggtcatgctc atatacaatc aactttcaat aatacaataa
    13861 taactttaac tgacgttcac ggaaatgcta tatcttgggc aagttctgga caattaggat
    13921 tcaaaggatc aagaaaatca actccatttg catctcaaat ggctgctgaa acagctgcaa
    13981 aagctgcgat ggaacacgga ctaaaaagtg ttgaggtatt cgtaaagggg ccaggttcag
    14041 gaagagaagc tgcaataaga gctttacaag caactggact agaagtaact atgataaaag
    14101 acgttactcc aatcccacat aacggatgca gaccaccaaa gagaagaaga gtgtaattaa
    14161 taagagtaca ataggaggtg tagataaatg gcaagatata caggtgcatc atgtagacaa
    14221 tgccgtagag agggaatgaa attattcctt aaaggtgata gatgttatac agacaaatgt
    14281 gctatagtaa aaagaaacta tgctccaggt caacatggcc aaggaagaaa gaaagtttct
    14341 aactatggat tacaattaag agaaaaacaa aaagttaaaa gaatatatgg agttttagag
    14401 actcaattta gaaatttata tgaacgtgct gaaaatatgc ctggtaaagc aggtgagaac
    14461 ttattaagtt tattagagag aagattagat aatgtagttt acagaatggg actagcatct
    14521 tctagaaaag aagctagaca attagtgact catggtcatt tcactttaaa tggaaataaa
    14581 gtagacatac cttcattaat agttaaggtt ggagatgtta tagaagttaa agagaaatca
    14641 agatcttctg caaaattcaa aaatttagta gaagttaact caagaatagc tcctaagtgg
    14701 ttagaagcta atgtagaagg aatgacagca aaagtagttg gtgttccaac aagagaagat
    14761 atagatcttg agatagcaga gcacttaatc atagaacttt actctaaata ataagcacac
    14821 ttttaaaaat tattttaaaa ttttgtttac cctcagtgga ttactgaatt ttaaggaggg
    14881 ttttgtccat gatagaaata gaaaagccaa aagtagatat agttgagctt agcgaagact
    14941 atagatatgg taagtttgtt atagagcctc tagaaagagg atatggaata actataggta
    15001 acgcattaag aagaatatta ttatcatcat taccaggtgt agcagtgaat gctataaaaa
    15061 tagatggagt tcttcatgaa ttttcaacaa tacctggtgt taaagaagat gttactgaga
    15121 taatattaac tttaaaagag ctttcagcaa ctatagatgg tgaaggaagt agaacactta
    15181 aaatagaagc tcaaggacca tgctctatca caggtgcaga tataatctgt cctccagatg
    15241 ttgaaatatt aagtaaagat ttagcaatag ctacattaga tgataatgct aaacttaata
    15301 tggagatatt tgtagataaa ggtagaggtt atgtttctgc tgaagaaaat aaaacagaga
    15361 atgttccaat aggtgtttta cctgtggatt caatatatac tcctgttgag aaggttagtt
    15421 atcatgtgga aaacacaaga gttggtcaaa aaacagatta tgataaatta gtactagaag
    15481 tttggactaa tggtagtata aatcctcaag agggaatatc attagctgca aaggtattag
    15541 ttgagcattt aaacttattt atagacttaa ctgaacatgt aagtagtgtt gaaatcatgg
    15601 tagaaaaaga agaagatcaa aaagaaaaag ttcttgaaat gactatagaa gaattagatt
    15661 tatcagttag atcatataac tgtttaaaga gagcgggaat taatacagtt gaagaattag
    15721 ctaataaatc tgaggatgat atgatgaagg ttagaaacct aggtaagaag tcattagaag
    15781 aggtaataca aaaactagaa gaacttggat tgggattaaa accaagtgaa gaatagcgag
    15841 caaaggaggg ataagaatgg ctaagtaccg taaattagga cgtgaaacag ctcacagaaa
    15901 ccttatgtta agaaacttag taacttgctt actaagaagt ggaagaatag aaactacagt
    15961 gactagagcg aaagaaactc gtagaatggc tgaaaagatg ataactcttg ctaagagagg
    16021 agatcttcat gctagaagac aagttttagc ttatgttatg gatgaaacag tagttaataa
    16081 cttattcaca gatttagctc caaaatatgc tgagagaaat ggtggataca ctagaataat
    16141 aaaaataggg ccaagaaaag gcgatgctgc tgaaatggct tttatagaat tagtatagta
    16201 aggaaaggat taggcttgat ggcttaatct tttttttatt tttttgacta aggtatgata
    16261 taataatgtg taaaatgatt tttataagtt attgcttact aaaaggagta tgagttaatg
    16321 gataatatag taaaggtaaa taatatttcg tttgagtata ttacagatga agcaaaactt
    16381 aaagcaatag ataatttaag cctagatgtt aaaaaaggag aatttgttgc gataatagga
    16441 cataatggtt ctggtaagtc tactttatct aaaaacttaa atgctattct tatgcctact
    16501 gaaggaaata ttcttattga tgatatggat actaaagaag aagaaagatt atgggatata
    16561 agacaaactg caggcatggt atttcaaaat ccagataatc aaatagttgc tactatagta
    16621 gaagaagacg ttgcatttgg acctgagaac ttaggtatag aaccaaaaga aataagacga
    16681 attgtagagg agtctttaaa aagtgtaggt atgtatgatt taagagatag acagcctcat
    16741 ttgttatcag gaggtcaaaa gcaaagagtt gcaatagcag gaattattgc tatgaggcct
    16801 aaatgtataa tatttgatga agcaacagca atgttagatc catctggaag aaaagaagtt
    16861 atgaaaacaa taaaaagact taataaggaa gaaaatataa ctgttataca tataacgcac
    16921 tttatggaag aagcagtaga agctgataga gttgtagtta tggaaaaagg aaagaaaatc
    16981 ttagagggaa ctcctagaga agtattcagt aaaataaaga tgttaaagga aatcggttta
    17041 gatgtacctt gtatgacaga gttatctagt ttattaatag aagaaggtat aaatattagt
    17101 agtgatatat taactgtgga tgagatggtg atggaattat gtcaattata gtaaagaatt
    17161 taacacatat atataatgaa gggatgcctt ttgcaagtaa ggcacttgat gatatttctt
    17221 ttgagattaa agatagagat tttgttggtc ttataggtca tacaggctca ggaaaatcta
    17281 cattaataca acatttaaat ggattactaa agccttcctc aggagaaata tttataaatg
    17341 attttaatat aacagataaa aacttgaatt taactgagat tagaaaaaga gtaggggttg
    17401 tatttcaata tccagaatac caattgtttg aagaaacgat tgataaagat atagcttttg
    17461 gaccctctaa tttaggctta gaggagtctg agatacataa cagggtaaaa gcatcaatgg
    17521 aagctgtagg acttgattat gagggattta aagacaaatc tccttttgaa ttatctgggg
    17581 gacaaaagcg tagagtagca attgctggag ttatagccat gaacccagaa gttctcatat
    17641 tggatgaacc aactgctggt cttgaccctg gtggaagaga tgaaattttt aacttaataa
    17701 aagacttaca tgaaaaaaag aatatgacta taatactatc atcacatagt atggatgata
    17761 tggcaaagtt agcaaaaact ttaattgtta tgaatcatgg tagcgtagaa tttatgggaa
    17821 ctcctagaga agtgtttaaa tcaaatgcta gtaaattaaa agatatagga ttagatattc
    17881 cacaagtttt agagcttgca ttgaaattga gagaaaaagg ctttgacatc agtgaggata
    17941 tattgacttt agaagaagca aaacaggaaa tattaaaagt tgtgagagga cgaggattat
    18001 gttaaaagat ataactatag ggcaatacta cccaacaagt tctgctattc ataaattaga
    18061 tccaaggata aagcttgtag cgacaattgt atttatggta tctatatttg tagtaaataa
    18121 attttggcct tatatagtag ttttattatg tttattagct atgataaaat tggctaatat
    18181 accagtcaaa tatattgtta agggtgttaa acctcttaaa tggattattt tgtttacatt
    18241 tcttataaat atttttttct taccaggtga tgaaatatgg tcatttggat ttttagctat
    18301 tacaaaacag ggtctaagac aagcaatttt tatggcaata agattaatat ttttagtagt
    18361 tggtacatca ttgcttactt taacaacttc accaatagaa ttaactgatg gaatagagag
    18421 attgttgaat ccatttaaga aaattggttt gccagttcat gaacttgcaa tgatgatgac
    18481 aattgcttta cgttttattc ctacattgtt agatgagaca gacaaaataa tgaaggctca
    18541 gatgtctaga ggtgcagatt ttgaaagtaa gaatcttata aatagagcaa agaatttagt
    18601 accacttttg gtacctttat ttgtaagtgc atttagaaga gctgatgaat tggctatggc
    18661 catggaggcc agatgttaca gaggtggaca taataggact aagatgagag agtctgttat
    18721 atcaagaagg gattatatgg catgtgtatt tcaggttgtt tatctgggag caattatagc
    18781 tactagattt atagcaattt aattaataag ttatagatat aatgaggtaa agtatgagaa
    18841 atataaaaat taaaatccaa tacaatggta agaattattg tggatggcaa aagcaacctg
    18901 attctttagg gatacaaggt acaattgaaa gggctatata tgatataaca aaagaagaaa
    18961 ccagtcttat agggtctggt agaactgatt caggagttca tgctattggt cagattgcaa
    19021 attttaaaat taattcaggt ataagtatag aaagtatacc aatggcacta aatgccaagt
    19081 tgccaaaaga catatcagtt atagaagcat gtgaagtaaa tgatgatttt cactccagat
    19141 acagtgcaaa aggtaaaaca tataaatatt tagtatataa tagcaagttt agaaatccaa
    19201 tacttagtga gatatcatat caagtaaaat atgaacttga ttttgataaa atgtgttcag
    19261 aagcaaaaag tttattagga acacatgatt ttaaaggttt tatgagttct ggttcatctg
    19321 taaaagatac agttagaacg atatatgata ttgatataag taaaaaagat gacttgatta
    19381 cttttgagat tagtggtaat ggttttttat ataacatggt gaggattatt gttggaacac
    19441 ttgttgatat gggtcgtggc agaattaacg aaccattttt agatataata caatcaaaaa
    19501 ctaggtcaag atgtggacat acagctccag cacaaggatt atttctcaaa aaagttcatt
    19561 attaacttga cacaccaggc tacatgtatt aaaatatatg agaatgtgtt aataagtcca
    19621 cttgccccgg acttgacata aacggtaaaa aaattttatg aaaagtagtt aaggagggac
    19681 agttatgaaa agttatatag ctaagccagc tgatgtacaa agaaaatggt acttagttga
    19741 tgctgaagga aaaacattag gtcgtttagc aacagaaatt gcgacagtat tgagaggtaa
    19801 acataaacca acatttactc ctcacgttga tggtggagat tttgttgttg tagtaaatgc
    19861 agaaaaaata gttttaagtg gtaagaaatt agatcaaaaa tattacagat accatactgg
    19921 ttatgtaggt ggattaaaag aaatatctta cagagatatg atggataaga aaccagaaga
    19981 agttatatca catgctgtaa gcggtatgtt acctaaaaat aaattaagaa gcagaatgat
    20041 gactagatta agagtatttg caggtgctga gcacactcat gcagctcaaa atccagaagt
    20101 tttaaacttt aaataagatt aataggtgaa aggaggagtt tataatggct aacgttcaat
    20161 attatggaac tggaagaaga aaaagttctg ttgctagagt aagactagtt gcaggtgaag
    20221 gaaatatatt agtaaatgga agagcattag aaaattattt taattatgag acattaataa
    20281 gagatgttaa acaaccatta gttttaactg gtaatgaaaa taaatatgat gttatagtaa
    20341 aagttgaagg tggaggattc actggacaag ctggagctat aagacatgga atatctagag
    20401 ctttattaaa agctgattta gatttaagac ctgctttaaa gaaagaaggt ttcttaacta
    20461 gagatgcaag aatgaaggaa agaaagaaat acggattaaa agcagcaaga agagctccac
    20521 aattctcaaa aagataatta cttatttttt tggaaaagca aaatccttta tttactgtta
    20581 ttcagaaagt attggtattt taaaaatgtt gggttaagtt aattattgat atataataaa
    20641 ataataagat atcttattag gatgtttttc attaagaaga acatcctttt tattttgact
    20701 atttaataaa aaacatatgc taataacatt taaattttat ttttataata ttgtaattta
    20761 aaagtttata taaggttata tattttaaga tattatttaa caatataaat tctgaatata
    20821 cgttatcaaa gtttataata taaactaagt ataatttatt gtatagtatt gaatgttaga
    20881 taaacatagt gaattaaata ggggcagaaa tataatatca ttacataata atatattaat
    20941 accaataaat aaagatatat caatattaaa aaaatttaaa tgtttgtact aatatatgga
    21001 atattatagt gtttttataa gtatacatat acagggtgat gttgtgagaa agtacataaa
    21061 acatataatt tttagttttg caatgatatg tctagtagta gtatccatat ttgaaattaa
    21121 aaatatttct gaagatgtta tcaagtatat gccagtaaca aacaaaacta taattttaga
    21181 tgctggtcat ggaggcattg atccaggtgc attaaataag gataagagta catctgaaaa
    21241 ggatattaac ctagcaataa cacttaagct tagagagctt atagaatcaa gtggtggcct
    21301 tgtaatatta actcgagaag atgacagtag cctttataaa gaagaaaata ataaaactac
    21361 aagacaaaaa tataatgaga atttgaaaaa tagaaaagaa ataatatcta attctaatgc
    21421 caatatgttt gtctctatac atcttaatgc atttgaacaa tcaaaatact atggagctca
    21481 aactttttat cctaaagaca aacaagacag taaagaatta tcgaagtgta ttcaagaaga
    21541 acttaaaaga gtagtagata agacaaacaa cagagaagtc aaaccaaggg atgatatata
    21601 tcttttgaaa gaaaataata ttccatcagt actgatagaa tgtggttttt tatcaaatga
    21661 aaaagagtgt aaactcttaa ctgatgaaac atatcaagaa aaaatagcat gggcaatcta
    21721 cataggaata caaaaatatt taagttgaaa taagtataaa aataggtcta aatatgtaaa
    21781 tagcttgtat taaagcagtt aaaatgcatt aatataggct atttttattt tgacaaaaaa
    21841 atatttaaaa taaaagttaa aaagttgttg acttagaata atatagatga tattatatat
    21901 gagtgcccaa aaggagcacc aaaataagac
//
LOCUS       DAMJYN010000066        21335 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.067, whole genome shotgun sequence.
ACCESSION   DAMJYN010000066 DAMJYN010000000
VERSION     DAMJYN010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21335)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21335)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21335
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.067"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            259..780
                     /locus_tag="PC466_002679"
     CDS             259..780
                     /locus_tag="PC466_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2770046.1"
                     /translation="MDIAKLILNPARLRILQYIRLHGSARTSDIVKYLNDIPRATVYH
                     HVKILEENNMIEVIKENRVRGTIEKVYALKEYTTSMEGETFVALSTAFYVGLMQEMNE
                     YFSRKEQDHKKDNVFFSSALLYMSDNEYENLLKSIADLLKPYIEQKPKSNLKLRKLSI
                     ISSPPVVDNDKTK"
     gene            814..1590
                     /locus_tag="PC466_002680"
     CDS             814..1590
                     /locus_tag="PC466_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF2770047.1"
                     /translation="MKFHEFGDKNKPHIMLIHGGGNAWWNYLRQAEVLSNNYHVILPT
                     LDGHGEEYETTYISTEDTADKLISYIDENCSGHLFALCGVSLGGQIVMELLSRKPNIT
                     KKAIIDGSICYPRPLMARFCIAGIRFFGGLLFSEKACRFQIAMMPKLLPENMQYPDEI
                     KAYYMTDMPHVRKETFYNMYRTYMMNYTLKENVKKTTAQVMYWYGEKEMKCVKKSAKM
                     FQSYVPSCEIYEAKGYNHGYLSLYLPNEWLEIAEPFFQKE"
     gene            1933..2886
                     /locus_tag="PC466_002681"
     CDS             1933..2886
                     /locus_tag="PC466_002681"
                     /EC_number="3.4.24.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GPR endopeptidase"
                     /protein_id="HDF2770048.1"
                     /translation="MINVRTDLALEASEMCEKSQEGSSIPGVKIETKELENCIVTKVE
                     VIDRQGAEIMNKDIGKYITLESNLMKFDDDESREEMISYLKEELVDIFGQDKNKKTLV
                     IGLGNRNITSDALGPKSVSKTLVTRHLFKNYNKDYDDDFTEVSALSPGVMGVTGIETS
                     EIVKSLVEKVKPDRVVAIDALASRKMERVNSTIQISTAGISPGGGVGNTRKSLTKETL
                     GVDVIAIGVPTVVDAATLTIDVLDMAIDNLIAQSEETESFYEMLKKLKEEEKYHLIKD
                     SLDPYDKNLIVTPKDIDDTIENLSIIISEGLNRSLHPGRLV"
     gene            2904..3923
                     /locus_tag="PC466_002682"
     CDS             2904..3923
                     /locus_tag="PC466_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein P"
                     /protein_id="HDF2770049.1"
                     /translation="MFKKCIKVVTLTFILACILPGKSLALNQDDFLKFLVNSSYPEAK
                     VEGNDTENKKNNKNKETSKENKEESKEENTKSKDASKVDNKKESEKEYIKLYVGKENV
                     PDIESKNSDTTETNTTSSSDYKDDLRVTKENPRILIYHTHGCETYSNSPDGNYHSRDK
                     KNSVMEVGSALTSALDSKGWGVVHTTKYHDYPSYNNSYASSLKTIQSILPKYNSVDIA
                     IDLHRDARDLTNPATKEKDHLKYTTMINGERVSKFFFVVGGKNTNRKQLRALAEDITA
                     FAEKKYPGLVSPIVEKDYARFNQFAVKNHMLVEIGNNATSVEESKATTKYLAEILDEY
                     FKQKN"
     gene            3954..4205
                     /locus_tag="PC466_002683"
     CDS             3954..4205
                     /locus_tag="PC466_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770050.1"
                     /translation="MSRLEKNIESKSKLRKYKYIMRILFLITMIIGTSVCVFIVDSNA
                     KSMLGMKQYDFPSIKFDITKFDFDIPNFDIHEIIKKFNK"
     gene            4487..6292
                     /gene="lepA"
                     /locus_tag="PC466_002684"
     CDS             4487..6292
                     /gene="lepA"
                     /locus_tag="PC466_002684"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HDF2770051.1"
                     /translation="MDNKQSRTRNFSIIAHIDHGKSTLADRLIQQTGLVSERDMKSQL
                     LDNMDLERERGITIKLQNIRLMYKAKDGNEYYLNLIDTPGHVDFNYEVSRSLAACEGA
                     LLVVDAAQGVEAQTLANVYLAIDQDLEILPIINKIDLPSARPEEVKNEIEDLIGLDSS
                     EAPLISAKTGLNIEDVLEDIVKNVPPPKGDNEAPLKALIFDSYYDAYKGVVAYVRVFE
                     GTVKKGMTIKMMNTNKKFEVTEVGVMAPGQTELSELSAGDVGYIAASIKDIRSCRVGD
                     TITDSNNPTEEPLPGYKKATPMVYCGIYPGEGEKYENVRDALEKLQVNDAALEYEAET
                     SAALGFGFRCGFLGLLHMEIMQERLEREFNLDIITTAPSVIYRVTKMDGEVVMIQNPA
                     NLPEPSEIKMIEEPIVKGDIIVPKDYVGVVMELCQERRGNMLNMEYIDERRVMLHYDL
                     PLNEVVYDFFDALKSRTRGYGSLDYEVKGYVASTLVKLDILINKEQVDALSFIVHETR
                     AFPRGKAMCEKLKGEIPRHQFAIPIQAAVGNKVIARETISALRKDVLAKCYGGDISRK
                     KKLLEKQKEGKKRMRQIGSVEVPQKAFMSVLKLDE"
     gene            6443..7780
                     /locus_tag="PC466_002685"
     CDS             6443..7780
                     /locus_tag="PC466_002685"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HDF2770052.1"
                     /translation="MINIEIPKKVDYIIKELETNGYEAYVVGGCVRDCLLERVPNDWD
                     ITTSARPEVVVELFEKTIPTGIQHGTVTVMIEHEPFEVTTYRIDGNYSDGRHPDSIEF
                     TNNIVKDLSRRDFTINSIAYNSKTGLVDPFNGYEDIQNKYIRCVGNPVDRFEEDALRM
                     LRAVRFSAQLNFKIAEGTKQSIHKKADLIKNVSIERIQTEFNKILVSDSSKLNLLKST
                     GLLKFIIPEICELEDVTQHNPYHIYDVQKHTLISTEVIEDELYLKLTMLFHDLGKKVT
                     KTTDKNGVDHFYTHSRESVKIAKKILRRLKYDNYTINKVLILIQYHDYRIEPKRKIIK
                     KLLNKLEDVELFEDLIKVNWADTLAKNPKYAKQKILNLIECEKEFKHIINQKECFNLK
                     DLAINGKDLISIGIKPGKDIGHILNKMLEIVINNPELNEKEILKEKALNIYTF"
     gene            8013..9326
                     /locus_tag="PC466_002686"
     CDS             8013..9326
                     /locus_tag="PC466_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDF2770053.1"
                     /translation="MHTQLQKTIGLSAALSTVVGMVIGSGVFFKPQAIYTTTNGAPGL
                     GIIAWLLGGFITITAGLTATEISAAIPKTGGMMIYIEEIYGEKLGFLTGWMQTVLFFP
                     GTSAALGVIFAQQASELLGMSPNNMANVLPIAIGVILFLALLNIIGSSLGGKVQTVAT
                     IGKMIPLILIIVFGFIKGQSSEVLNPFVGDGVNASNALGQVLIATLFAYDGWINVGAI
                     SGEMKSPEKDLPRAIVGGLSLVMAVYIIINIAYLWVVPASELATVTSPATLVATRLFG
                     NIGGKVITVGILISVFGTLNGYLLTGSRIPYTLAEMGTLPASKTLLKVNSGGSPVNSI
                     LLITVLACVYALSGQFNLLTDLTIFSIWVFYVLTFIGVMRLRRQKPDLHRPYKVPLYP
                     IIPIIAILGGLFVIINQILTSTIISLGGIFITLLGLPVYYYMKKR"
     gene            9498..10673
                     /locus_tag="PC466_002687"
     CDS             9498..10673
                     /locus_tag="PC466_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HDF2770054.1"
                     /translation="MLGLYVHIPFCVKKCKYCDFNSYKMDIDSKKRYIEDLKIEMKLY
                     SNKLYKDNKYKNKECCSLNKNDKITSIFVGGGTPSILTSDEIREVFISIKEMFDIDEN
                     AEITIECNPGTLTLEKLKTMKEIGINRLSIGLQAIQEKHLNFIGRIHTYEEFEKNYKD
                     ALSVGFKNINVDLMYSLPNQTLCDWKETLEKVVHLNPTHISAYSLILEEGTELYNMYE
                     SNKFELIDENVDIEMYEYTINYLKSKGYNQYEISNYSKEGYNCEHNILYWECEHYIGI
                     GAGASGYINENRYNNVESLEDYHLSLVKREKPIQENEILSEKDMIEEKIFMGLRMNKG
                     IKFEDFKKKFGIDFREKYNKQIEMLLARKLINQSFEGIQLTQKGREISNSVFIEFME"
     gene            10776..11795
                     /gene="hrcA"
                     /locus_tag="PC466_002688"
     CDS             10776..11795
                     /gene="hrcA"
                     /locus_tag="PC466_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcription repressor HrcA"
                     /protein_id="HDF2770055.1"
                     /translation="MELNERKLNILKAIVKDYIETAEAIGSRTISKRHDLGVSAATIR
                     NEMADLEELGYLIQPHTSAGRVPSEKGYKLYVNSLMSKSELDDNDKILIEQCMNHNIN
                     HIKELIHETSKLLSQLTNYTTVAVTKSLINQSVIKHIQLVAMNDNNILLIVVTDKGDL
                     KKANLTTNVYLDQSKLNLISDNLTRKLLGKSITDLDDNLIAFIKYEISEYSGLIDELL
                     NALNSNMKEEDFSLSLNGATNIFSYPEFNDVLKAKSFLNMLEKKETIADIIKSKGIQK
                     DNLNIIIGSDNDCELAQDCSIVTATYNVDRDLVGRISFIGPTRMDYARIYSIINYMSL
                     LINRK"
     gene            11825..12445
                     /gene="grpE"
                     /locus_tag="PC466_002689"
     CDS             11825..12445
                     /gene="grpE"
                     /locus_tag="PC466_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HDF2770056.1"
                     /translation="MDKKNEQQEVREENDTSINQESETQVELEEEVVNEECETSSEKT
                     DEKEVDDENVTDINSKLAEKKLQDELDELNDKYQRLQAEYANYRRRTQQEKETIGVFA
                     NEKIITELIPVIDSMERALDACEDKEDTMYKGISLVHKQLIDTLVKFGVEEIEAESKE
                     FDPNLHLAVMQESVDGVEANQIVMVLQKGYKLGTKVVRPSMVKVSC"
     gene            12537..14384
                     /gene="dnaK"
                     /locus_tag="PC466_002690"
     CDS             12537..14384
                     /gene="dnaK"
                     /locus_tag="PC466_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000034699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HDF2770057.1"
                     /translation="MGKIIGIDLGTTNSCVAVLEGGEAQIIANSEGMRTTPSVVAFTK
                     DGERIVGEPAKRQAVTNADKTITSIKTHMGTDYKVNIDGKSYTPQEISAIILQKLKSD
                     AESYLGQTVTEAVITVPAYFTDAQRQATKDAGRIAGLDVKRIINEPTAAALAYGMDKL
                     DQEKKILVFDLGGGTFDVSILEIGDGTFEVLATAGNNRLGGDDFDQIVIDYLADEFKK
                     AEGVDLRNDKMALQRLKEAAEKAKKELSSTMSSNINLPFITATAEGPKHLNIDLSRAK
                     FEELTRGLVEKTMEPTKTALQDAGLSTGDIDDVLLVGGSTRIPAVQEAVKKFIGKEPH
                     KGINPDECVAAGASIQAGVLAGDVKDLLLLDVTPLSLGIETMGNVMTKIIERNTTIPT
                     KKSQIFSTAADNQTAVDIHVLQGERSMAYDNTTLGRFQLTDIPPAQRGIPQIEVTFDI
                     DANGIVNVSAKDLGTGKEQKITITSNTNLSEAEIEQKIKEAEMNAEADKQKKEKIEAF
                     NQAESTIYQTEKTLNELGDKISSGEKEDIEKAIADLKAVKDNQDATAEELKKATDEVM
                     TKFQKVSQEMYQKAAQEQQAAQGAEQAQDNGPKDDNVVDADFKEVDEDK"
     gene            14595..15749
                     /gene="dnaJ"
                     /locus_tag="PC466_002691"
     CDS             14595..15749
                     /gene="dnaJ"
                     /locus_tag="PC466_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HDF2770058.1"
                     /translation="MSTKRDYYEVLGISKDAEAQEIKKAYRKLAMKYHPDRNPGDKEA
                     EEKFKEINEAYEVLSDDTKRKTYDQFGHDGLNGQGGFGGQGGFGGQGFGGFEDMFGDI
                     FGDMFGGSFGGGRARRRGPQRGADIRQSVTISFEEAAFGKKMSIKVNRSEECEECNGT
                     GAKPGTSKKTCSTCNGTGQVRTVQRTPFGNIASSRPCSACNGTGEVIESPCSKCHGTG
                     NTRKVKTIEVDIPAGIDDGQMIKLSGQGEVGEKGAPRGDLYIVVNVKSHPLFTRDGND
                     IYFEMPITFVQATLGDEIEVPTLDGKVKYSVPEGTQTGTVFRLKEKGIPRIRGNSRGD
                     QYVKVVVEIPKKLNDKQKELLREFAKECGSNVHEKKKTFGQKIEDMFKKK"
     gene            16715..17650
                     /locus_tag="PC466_002692"
     CDS             16715..17650
                     /locus_tag="PC466_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HDF2770059.1"
                     /translation="MYYIGVDIGGTGIQAGVVDNYGKIIFRSECKTVIEKGFEGILND
                     IKIMIYKLLEDNKLTMSDIKSIGFGVPGFINKEGLVTCVNLKWNKKAFNKELKRRFPD
                     AEIHGENDATVAALGEAKFGSMKGANVGVLYTLGTGVGGGIVINQKVFSGAHGLGSEI
                     GHQIIGENYFNCNCGNNGCVETFCSATAIIKYSQKLIEEGEKSRILDLAEGNLENVNA
                     KMVFDAYRENDLVAIKVINRFKDYLAKTFANTINSLDPEIISIGGGISKSSDIILDGI
                     EDLVRKFVLYKTEDIATITCATLGSDAGIIGAAFL"
     gene            17686..19059
                     /locus_tag="PC466_002693"
     CDS             17686..19059
                     /locus_tag="PC466_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2770060.1"
                     /translation="MGKTNARRTLFLIAIGSGTMLNPLNSSMISLALHSIQNDFHISF
                     TTVSWIVSAFYLASAIAQPVSGKIGDLIGRKVLFLSGLMLVILSASIVPLVQSFFILI
                     FIRVIQAIGTSTLYPSGVALIQNNIKERQSSALAVLTIFASTTAGLGPTLGGLLLDLG
                     GWHAIFLVNIPVVLVSICLGYFLFPKEVKEKKSIKETLKNVLSRLDIIGILLFSIAMI
                     FILLFLLSMKESFNLEQLVFGIILMCLFIWHELRTKLPFIDIKLFVSNPKLSKVYLQF
                     IILNFFNYILFFGLPSYFQDALHYSAKSTGLFMLFMSGIGIFISPLTGKWIDKSGTRF
                     PLVTSSIFMFISAVLLSVVFIHIPVIGKGIILSLAGISYGVGNVALQSSMFEESPRDS
                     IGTASGLFQTSRYLGSILATVLLGMVFEGNITSEQFQILGYVMVVLGTISFLLNFILK
                     KELRKVE"
     gene            complement(19247..20014)
                     /locus_tag="PC466_002694"
     CDS             complement(19247..20014)
                     /locus_tag="PC466_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2770061.1"
                     /translation="MEELKDFLERQLNKKINIYPYENQKLDASSHLVTFNNAIYVIDF
                     LDKNNLDNLKGNFYLIYQSHIDFEYLKNIFYNLFEDINIIQHNGFFIVNSKYNLDINV
                     TTQNIIETETYQSTYIFYLGELDSKADFYFRLQLCSDLLPHIIKDNAENKFLNLFDLI
                     RYKTLDLINEDNILNKLIDFNKIKSIDEELLYTGIKFINNDLNISKTSTSMFLHRNTL
                     VYRLEKINEILGFDLKNFENAMIFYLSVKSYFLYKKI"
     gene            complement(20044..21153)
                     /gene="ugpC"
                     /locus_tag="PC466_002695"
     CDS             complement(20044..21153)
                     /gene="ugpC"
                     /locus_tag="PC466_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003242648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HDF2770062.1"
                     /translation="MSEVILKNISKLYSNGFNAVKNINIDIKDKEFIVLVGPSGCGKS
                     TTLRMIAGLEEISEGELYIGDKLVNDIEPKDRDIAMVFQNYALYPHLSVYENMAFALK
                     LRKLPKDEIDKKVKEAAKILDLLPLLNKKPKTLSGGQRQRVALGRAIVRNPKVFLMDE
                     PLSNLDAKLRTAMRTEITKLHQQLGTTFIYVTHDQVEAMTMADRIVVMKDGVVQQIAT
                     PQDVYDYPANIFVAGFIGAPQMNFIDVILIEENDKIYAQNEHIKLKLNKEKHYDLIKD
                     NYINNEVVIGIRPEDIHVEDTFIKSNPDTCFKSRIEIKELMGAETYAHLKLGENTITI
                     RFDSKNRINVGDDLTLSVDNSRVHIFDKETTLAIR"
BASE COUNT         8348 a         2403 c         3752 g         6832 t
ORIGIN      
        1 ataaaaatat aaatttatat gcttaattaa gataattttt ccaataatca agataatttt
       61 tttcattagt atgtatgata gatgcatcaa acaatataac taatatgtta gaaggttata
      121 tgtaattaat ctcagtgttt atatagaata gcatttgtag catttattat agttgtaatt
      181 actacttata tcatagactt gaatagtcta aaaaaataga ctataatatt tttatagact
      241 aaagaaaggg ctgataagat ggacatagca aaactaattt taaatcctgc aaggcttcgt
      301 atcttacaat atattcgact tcatggcagt gctcgcacat ctgatattgt aaagtattta
      361 aatgatattc ctcgtgcaac agtttatcac catgtaaaaa ttttagaaga gaacaatatg
      421 attgaagtaa ttaaagaaaa tcgtgtgcgt ggtactattg aaaaggttta tgcactaaag
      481 gaatatacaa catctatgga aggagagacc ttcgttgcac tttctacagc attttatgta
      541 ggtctgatgc aggaaatgaa tgaatacttt agcagaaaag agcaagacca taaaaaggat
      601 aatgtatttt tctcttcagc attactatat atgagtgata atgaatatga aaatcttctt
      661 aaaagtatag ctgatttatt gaaaccatat atagaacaaa agcctaaatc aaatctaaaa
      721 cttagaaaac tttcaattat atcttctcca cctgtggttg ataatgataa aacaaaataa
      781 catgaatctt atttttataa aaggaggttg tatatgaaat ttcatgaatt tggagataaa
      841 aacaaaccac atattatgtt gattcatggg ggagggaatg cgtggtggaa ctatttgcga
      901 caagcagaag ttttgtctaa caactatcat gtgatacttc ctacattgga tggtcatgga
      961 gaagaatatg aaacaacata catttctaca gaggatacag cagataagtt gatatcatat
     1021 atagatgaaa attgcagtgg acatcttttc gctttgtgtg gggtatcact tggtggtcaa
     1081 attgtcatgg aacttttatc tcgaaaacct aatattacta aaaaagcaat tattgatggt
     1141 agtatttgct acccaagacc tcttatggca aggttttgta ttgctggtat tcgatttttt
     1201 ggaggacttt tgtttagtga gaaggcttgt cgctttcaaa ttgctatgat gccaaaattg
     1261 ttacctgaaa atatgcaata tccagatgaa ataaaagcgt attatatgac agatatgcca
     1321 catgtaagaa aagaaacatt ctataatatg tatcgtactt atatgatgaa ctatacactt
     1381 aaagagaatg ttaaaaaaac cacagcacaa gtaatgtact ggtatggaga aaaagaaatg
     1441 aagtgcgtta aaaaatctgc aaaaatgttt cagtcttatg taccctcttg tgagatttat
     1501 gaagctaagg gctataatca tgggtattta tcgctttatc ttccaaatga atggttggaa
     1561 attgcagaac catttttcca aaaggaataa aggtgttagg tgattattgt ataattattg
     1621 ctgttttttt atatagtaaa taaattaggt ataaatataa aaaagttatt ttagttaata
     1681 tattagtgaa agcttaatag gaaaattata aatagattaa aggtagcgcc tatataaata
     1741 gttgctacct ttttttgctt gtaaataaat gatagataag aaagtttact gacaaatcac
     1801 tgactaaacc caattttctt acattgaaag ccttaatttt acttgtttta aataaattta
     1861 caatttcttg ttataaaata ctaaattttg ttaacaatta taattagcat ttaatttata
     1921 ctggaggttt atatgattaa tgtaagaaca gatttagctt tagaagctag tgaaatgtgt
     1981 gaaaagtctc aagaaggaag tagtattcct ggtgtaaaaa tagaaactaa agaattagaa
     2041 aattgcattg taactaaagt tgaagtaata gacaggcaag gcgcagagat aatgaataaa
     2101 gatataggaa agtatataac tctggaaagt aatcttatga agtttgatga tgatgagtcg
     2161 agagaagaaa tgataagtta tttaaaagag gagttagtag atatatttgg ccaagacaaa
     2221 aataaaaaaa ccctggtaat tggtcttgga aatagaaata ttacttctga tgcgttagga
     2281 ccaaagagtg tatcaaaaac acttgtaact agacatcttt ttaaaaatta taataaagac
     2341 tatgatgatg atttcactga ggtatcagct ttaagcccag gagttatggg tgttactgga
     2401 atagaaacta gtgaaatagt aaagtcattg gttgaaaaag taaaaccaga tagagtagta
     2461 gcaatagacg cattggcttc aagaaaaatg gaaagagtaa actctactat acagatatca
     2521 acagcaggaa tatcacctgg tggaggtgtt ggcaatacta gaaaatctct aactaaagaa
     2581 actttaggcg tggatgttat tgcaataggc gttccaacgg tggttgatgc agcaactctt
     2641 acaatagatg tcttagatat ggcaatagac aatttaatag ctcaatcaga agaaacagaa
     2701 agtttttatg aaatgttgaa aaaacttaaa gaagaagaaa aatatcatct aataaaagat
     2761 tcgttagacc catatgacaa gaacttaata gtaacaccaa aggatataga tgatacaatc
     2821 gaaaatctat ctataataat aagtgaaggc ttaaataggt ctttacatcc aggtagattg
     2881 gtataaaata aggaggagca attatgttta aaaaatgcat taaagtagta accttgactt
     2941 ttatattagc atgcatttta ccaggaaaat cattagcttt gaatcaggat gattttttaa
     3001 agtttttagt aaattcatct tatccagaag ctaaagtcga aggaaatgat acagaaaata
     3061 aaaagaataa taaaaataaa gaaacaagca aagaaaataa ggaagaaagt aaagaagaaa
     3121 acactaaatc taaagatgca agtaaagttg ataataaaaa agagagtgaa aaagaatata
     3181 taaaacttta tgttggtaaa gaaaatgttc cagatattga gtcaaaaaat tcagacacaa
     3241 ctgaaactaa cacaacatct agttcagatt ataaggatga tttaagagta accaaagaaa
     3301 atccaagaat tttgatatat catactcatg gatgtgagac ttattcaaat tcacctgatg
     3361 gaaattatca ttcaagagat aagaaaaatt cagtaatgga agtaggaagt gcattaacta
     3421 gtgctttaga tagcaaagga tggggtgtag tccatactac taaataccat gactatccat
     3481 cttataataa ctcttatgca agtagcttaa aaacaataca aagtatatta cctaaatata
     3541 actcagtgga tatagcgata gacttacata gagatgctag ggatttaact aatccagcca
     3601 ctaaggaaaa agaccattta aaatatacaa ctatgataaa tggagagaga gtatcaaagt
     3661 tcttctttgt tgtaggaggt aaaaatacaa atagaaaaca acttagagct ttagcagaag
     3721 atataactgc ttttgctgag aaaaagtatc ctggtctagt atctccaata gtagaaaaag
     3781 actatgctag attcaatcag tttgcagtta agaatcatat gttagtagaa atagggaata
     3841 acgcaacaag tgtagaagaa tctaaggcta ctacaaagta tttagccgag attttagatg
     3901 aatattttaa acaaaaaaat tagagcttta agttataatt aggagcatgc taaatgagcc
     3961 gattagaaaa aaatatagaa agtaaaagta aactaagaaa atacaagtat attatgagaa
     4021 tcttattttt gattactatg attataggta catcagtttg tgtatttata gtagacagta
     4081 atgcaaaaag tatgctagga atgaaacaat atgattttcc aagtattaaa tttgatataa
     4141 caaaatttga ttttgacata ccaaattttg atatacatga aatcataaaa aaatttaata
     4201 agtagtaata agtgaataag gtttattgat taaaataagc cttattttag ttatatattt
     4261 ttaatgtata aaataaaaat tcattaactg tattttatag gatttacttt aagtttacga
     4321 tattatataa tatttagtgt tagacttgat aatccacata taatgtggat aattttgttt
     4381 agtgccaatt agtttatatt caaaaatttt aaatttggta tataaagagt ttttagataa
     4441 tgtaaaataa taactataag aataatcaag aggagggaat tttaaggtgg acaataaaca
     4501 aagtagaact agaaatttta gtataattgc acatatagac catggaaagt ctaccttagc
     4561 tgatagatta atacaacaaa ctgggcttgt tagtgaaaga gacatgaaaa gtcaattact
     4621 tgacaatatg gaccttgaaa gagaaagagg aatcactata aagcttcaaa acataagatt
     4681 aatgtataaa gcgaaggatg gaaatgaata ttatttaaat cttatagata cacctggaca
     4741 tgtagacttt aactatgagg tatcaagaag tttagctgca tgtgaaggag cactattagt
     4801 agttgatgca gctcaaggtg ttgaggcaca aactttagcc aatgtttatc ttgctataga
     4861 ccaagattta gaaatattac caataataaa taaaatagat ttaccaagtg caagaccaga
     4921 ggaagtaaaa aatgaaatag aagatttaat agggcttgat tcaagtgaag ctcctcttat
     4981 ttcagctaaa actggtttaa acatagaaga tgttttagaa gatattgtaa aaaatgttcc
     5041 tccacctaag ggagataatg aagctccatt aaaggcatta atattcgatt cttactatga
     5101 tgcttacaaa ggtgttgtag cttatgttag agtatttgaa ggaactgtta aaaagggtat
     5161 gacaataaaa atgatgaata ccaataaaaa gtttgaggta actgaagttg gtgttatggc
     5221 tccaggtcaa actgaactta gtgaattatc agcaggtgat gttggttata ttgctgctag
     5281 tataaaagat ataagaagtt gtcgtgttgg tgatacaata acagattcaa ataatcctac
     5341 agaagaacct ttaccaggat acaaaaaagc tactccaatg gtatattgtg gtatatatcc
     5401 aggagaagga gaaaagtatg agaatgttag agatgctctt gaaaagcttc aagtaaatga
     5461 tgctgcactt gaatatgaag ctgagacttc agcagcacta ggatttggtt ttagatgtgg
     5521 tttcttaggt cttttacata tggagataat gcaagaaaga cttgagagag aatttaacct
     5581 tgatataatt actacagctc catctgttat atatagagtt acaaaaatgg atggagaggt
     5641 tgtaatgata caaaatcctg caaacttacc agaaccatct gagataaaga tgatagaaga
     5701 gcctatagta aaaggagata taatagttcc taaagactat gtgggtgttg ttatggagct
     5761 ttgccaggaa agacgtggaa atatgttaaa tatggaatat atagatgaga gaagagtaat
     5821 gcttcactat gaccttcctc tcaatgaagt tgtttacgat ttctttgatg ctttaaaatc
     5881 gagaactaga ggttatggtt ctcttgatta tgaggttaaa ggttatgtag catctacact
     5941 tgtaaaactt gatatattaa tcaataaaga acaagtggat gcacttagtt ttattgtcca
     6001 tgagacacgt gctttcccta gaggaaaggc aatgtgtgag aaattaaaag gagaaattcc
     6061 aagacatcag tttgctatac ctatacaagc tgctgttggt aataaggtta ttgcaagaga
     6121 aacaataagc gctctaagaa aagatgttct tgctaaatgt tatggtgggg atatatctcg
     6181 taagaagaaa cttcttgaaa agcaaaaaga aggtaagaag cgtatgagac aaattggttc
     6241 tgttgaagtt cctcaaaaag catttatgtc tgtacttaaa ctagatgaat aaattcttat
     6301 aaatttagat aaatatattt aaaagctaga gtgattttag aattatttct aaattaatct
     6361 agcttttttg tggtatattt taagtaaact catagagaat ataagtaaga atatattaaa
     6421 gaagaataaa aaggtgatat ttatgattaa tatagaaatt cctaaaaaag tagactatat
     6481 aattaaagaa ttagaaacga atggttatga agcttatgta gttggaggat gcgttagaga
     6541 ttgtttatta gaaagagttc caaacgattg ggatataaca actagtgcta gaccagaagt
     6601 ggtagtagaa ttatttgaaa aaacaattcc aactggtata caacatggga ctgtaacagt
     6661 tatgattgaa catgaaccat ttgaagtgac aacttataga attgatggaa attatagtga
     6721 tggtagacat ccagattcaa tagaatttac aaataacata gttaaggact tgtcaagaag
     6781 agattttact atcaattcaa ttgcatacaa ttcaaagaca ggattagtcg acccatttaa
     6841 tggctatgaa gatatacaaa ataagtatat acgttgtgtt ggaaatccag tagatagatt
     6901 tgaagaagat gcacttagaa tgcttagggc agttagattt tcagcacaac ttaattttaa
     6961 aatagctgaa ggtactaagc aaagtattca taaaaaagca gatttgataa aaaatgtttc
     7021 tatcgaaaga atccagacag agtttaataa aatattagta tctgattcat ctaaattaaa
     7081 cttattaaaa tcaacaggtt tgttgaaatt tataattcct gaaatatgtg aattagaaga
     7141 tgttactcaa cacaatccat atcacatcta tgatgtacaa aaacatactt taatatctac
     7201 agaagtaatt gaagatgaac tgtatttaaa acttacaatg ttgtttcatg atttaggtaa
     7261 aaaagtaact aaaacaactg ataaaaatgg tgttgaccat ttttatactc atagtagaga
     7321 atctgtaaag attgcaaaga agattttgag aagacttaag tatgataatt atactattaa
     7381 taaagtttta atattaatac aatatcatga ttatagaata gaacctaaaa ggaagataat
     7441 taaaaagtta ttaaataaac ttgaagatgt tgaattattt gaagatttaa taaaagttaa
     7501 ttgggctgat acacttgcca aaaacccaaa gtatgcaaaa caaaagatat taaatcttat
     7561 tgagtgtgaa aaagaattta aacatataat aaatcaaaag gagtgcttta atcttaaaga
     7621 tttagctatt aatggaaaag atttgatatc tataggtata aaaccaggta aagatatagg
     7681 acatatttta aataagatgc ttgaaatagt cataaataat ccagaattaa atgaaaaaga
     7741 aatactaaaa gaaaaagcat taaatatata tacattttag attcaaatat aaaaaattta
     7801 attactttaa aaaattatag aagaaaatac ttatttagat aaaataaata atttttagag
     7861 aatattttag aagttacgat tgtatgattt ttaaacgcat agcatttact ctaggactat
     7921 agactaatat aaaaaaaaac tttgggaata ctaaaaccat aaatttataa aattaatatt
     7981 ttatatactg taaaacagtg aggagggaca gtatgcatac tcaactacaa aagactattg
     8041 gtctttcagc ggctctttct actgttgtag gtatggttat aggttcggga gtttttttta
     8101 agccacaagc aatatacact acaactaatg gagctccagg tctaggtatt atagcgtggc
     8161 ttttaggtgg ttttataaca ataactgctg ggcttacagc tacagaaatt tcagctgcta
     8221 taccaaaaac tggtggtatg atgatttata tcgaagaaat atatggagaa aagttaggct
     8281 ttttaactgg atggatgcaa actgtattat ttttcccagg tacatcagca gcattaggag
     8341 taatatttgc tcaacaagca tctgaacttt taggaatgag cccaaataat atggcaaatg
     8401 tacttcctat agcaattgga gttatactat ttttagcgtt attaaatata ataggttcat
     8461 ccttaggagg aaaagttcag acagtagcca ctattggaaa gatgatacct ttaattttaa
     8521 taatagtctt tggatttatt aaaggtcaaa gtagtgaagt attaaatcca tttgtaggag
     8581 atggtgtaaa tgcatcaaat gcacttggac aagtattaat agctactttg tttgcatatg
     8641 atggttggat aaatgttgga gctatatcag gagaaatgaa gtctccagag aaagatttac
     8701 caagagcaat agttggtggt ttatcattag ttatggcagt ttatattata ataaatatag
     8761 cttatctttg ggtagtacca gcaagtgaat tagcaacagt tacttcccca gctacattag
     8821 tagcaacaag attgtttgga aatataggtg gaaaagtaat aactgtgggt atattaatat
     8881 cagtatttgg gacattgaat ggatatttat taacaggttc aaggatacct tatacattag
     8941 ctgaaatggg aactttacca gcatctaaaa ctcttttaaa agtaaattct ggaggttctc
     9001 ctgtaaattc aatactactt ataactgtgt tagcctgtgt atatgcatta tctggtcaat
     9061 ttaatctttt gacagactta actatatttt caatatgggt attttatgta ttgactttta
     9121 taggtgttat gaggcttaga agacaaaagc cagatttaca cagaccatat aaagtccctt
     9181 tatatccaat aataccaatt atagctatac taggtggact gtttgtaata ataaatcaaa
     9241 tattgacttc aacaattata tctttaggtg gaatatttat aacactatta ggtttaccag
     9301 tttattatta tatgaaaaaa agataactac ttaatttaag ttagataaat ttgggtaaag
     9361 gtgaaaatta acttttatcc aaatttttta tactgttata caatataagc attatatatt
     9421 acttgatgtg ttattttgtt tgatttataa tttagtaatt gatgctttaa gataatttaa
     9481 gaaatgagga ataaaaaatg ctaggacttt atgtacatat tccattttgt gtgaaaaaat
     9541 gtaagtattg tgattttaat tcttataaaa tggacataga ttcaaaaaaa agatatatag
     9601 aagacttaaa aatagaaatg aaattatata gtaataaatt atataaagat aataaatata
     9661 aaaataaaga atgctgtagt ctaaataaaa atgacaaaat aacgagtata tttgtagggg
     9721 gaggtacacc tagtatacta acatctgatg aaataagaga agtatttata agtataaaag
     9781 aaatgtttga tatagatgag aatgcagaaa taactataga gtgtaatcct gggacattaa
     9841 cattagaaaa attaaaaact atgaaagaga ttggcataaa tagacttagt atagggctac
     9901 aggccattca agaaaagcat ttgaatttta taggaagaat acatacttat gaagaatttg
     9961 agaaaaacta taaagatgca ttaagtgtag gttttaaaaa tattaatgta gatttaatgt
    10021 acagtcttcc aaatcaaact ctatgtgact ggaaggaaac tcttgaaaaa gttgtacact
    10081 taaatccaac acatatatca gcgtattccc ttatactaga agaaggaact gaactatata
    10141 atatgtatga aagtaataaa tttgagctta tagatgaaaa tgtagatata gaaatgtatg
    10201 agtatacaat aaactactta aagtcaaaag gatataatca atatgaaata tcaaattact
    10261 caaaagaagg ctataattgt gagcataata ttttatattg ggaatgtgaa cattatatag
    10321 ggattggagc aggagcttct ggctatatta atgagaacag atacaataat gtagaatctt
    10381 tagaagatta tcatttaagt ttggtaaaaa gagaaaaacc aatacaagaa aatgaaattc
    10441 tttctgagaa agatatgata gaagaaaaga tatttatggg gcttagaatg aataaaggca
    10501 taaaatttga agattttaaa aaaaaatttg gaatagattt tagagagaag tataataagc
    10561 aaatagaaat gctattagct agaaagctta taaatcagag ctttgaaggt atacaattaa
    10621 ctcaaaaagg aagagaaata tctaatagtg tatttataga atttatggaa taatttttaa
    10681 ggtgttgaca aaataaattt ataatggtat ataatatata taatcttttt agcactcgaa
    10741 cttagtgagt gctaacagct aggaggtata ataatatgga attaaatgaa agaaaattaa
    10801 atatcctcaa agctatagtt aaagattata tagaaacagc tgaagctata ggttctagaa
    10861 caatatctaa aagacatgat ttaggtgtta gtgctgctac cataagaaat gaaatggctg
    10921 accttgaaga attagggtat ttaattcagc ctcatacttc tgcgggtaga gttccatctg
    10981 aaaaaggcta taagttatat gtaaactctc ttatgagtaa aagcgaattg gatgataatg
    11041 ataagattct tattgaacaa tgtatgaatc ataatataaa tcatataaaa gaattgattc
    11101 atgaaacctc taagctatta tcgcaactaa caaactatac aactgtagca gttactaaga
    11161 gtttaataaa tcaaagtgtt ataaagcaca tacagttggt tgctatgaat gacaataata
    11221 ttttacttat agttgtaaca gataaagggg acttaaaaaa agctaacctt acaactaatg
    11281 tatatttaga tcaatctaag ttaaatttga tttctgataa tcttacaagg aagcttttag
    11341 gtaaaagtat aacagatttg gatgataatc taattgcttt tattaaatac gaaataagtg
    11401 agtattctgg acttatagat gagcttttaa atgctttgaa ctcaaatatg aaagaagaag
    11461 atttttctct atcattaaat ggagctacta acatatttag ttatccagaa tttaatgatg
    11521 tattaaaagc aaagtcattt ttaaatatgt tggaaaaaaa ggaaacaata gctgacataa
    11581 ttaaatcaaa gggaatacaa aaagacaatc taaatataat aattggtagt gataatgatt
    11641 gtgaactggc acaggattgt agtatagtta cagcaactta taatgtagat agagacttgg
    11701 ttgggcgaat aagctttata ggccctacca gaatggatta tgctagaatt tactctataa
    11761 taaattatat gagtttatta attaatagaa agtaaagaaa ttttaaattg cgaggtgtaa
    11821 agtcttggat aaaaaaaatg agcaacagga agtaagagaa gaaaatgata cttctattaa
    11881 ccaagaatcg gaaactcaag tagagttaga agaggaagtt gttaatgaag aatgtgaaac
    11941 atcaagtgaa aaaactgatg aaaaagaagt tgatgatgaa aatgtaacag atataaattc
    12001 taagttagca gaaaaaaaat tgcaggatga gttggatgaa ttaaatgata aatatcaaag
    12061 acttcaagcc gaatatgcaa actacagaag aagaactcaa caagagaaag agacaatagg
    12121 cgtatttgca aatgaaaaaa taataactga gttgatacca gttatagata gtatggaaag
    12181 agccttagat gcatgtgaag ataaggaaga tactatgtat aagggtataa gccttgtaca
    12241 taaacaatta atagacactt tggtaaaatt tggagtagaa gaaatagaag cagaatctaa
    12301 ggaatttgac cctaatctac atctagcagt tatgcaagaa agtgtagatg gagttgaagc
    12361 aaatcaaata gtaatggtac ttcaaaaagg atataagcta ggaactaaag ttgtaagacc
    12421 ttcaatggtt aaagtttctt gctaagtata aattaaaggt taaattattt aacctaatat
    12481 aaaatattaa aataagtaaa acttaattat ataattactc gaggaggatt ttagtcatgg
    12541 gaaaaataat aggaatagat ttaggaacaa caaattcatg tgttgcagtg ttagaaggtg
    12601 gagaagcaca aataatagca aatagtgaag gtatgagaac tactccatca gtagtagcat
    12661 ttacaaaaga tggtgagaga atagttggag aacctgcaaa aagacaagca gttacaaatg
    12721 cagataaaac aataacttct ataaaaactc atatgggaac tgattataaa gtaaatatag
    12781 atggaaaatc atatactcca caagaaatat cagcaataat attacaaaaa ttaaaatcag
    12841 atgcagaaag ttacttagga caaacagtaa cagaagcagt tataacagta ccagcttact
    12901 ttacagatgc tcaaagacaa gcgactaaag atgctggtag aatagcaggg cttgatgtta
    12961 agagaataat aaatgagcca acagcagcag ctcttgctta tggtatggat aaattagacc
    13021 aagaaaagaa aatattagta tttgacttag gtggaggaac ttttgacgta tctatacttg
    13081 aaataggaga tggaactttt gaagttttag ctacagctgg taacaataga ttaggtggag
    13141 atgactttga ccaaatagta atagattatt tagcagatga atttaaaaaa gctgaaggtg
    13201 tagatttaag aaatgataaa atggctcttc aaagattaaa agaagcagca gaaaaggcta
    13261 agaaagaatt atcatcaaca atgagttcaa acataaactt acctttcata actgctacag
    13321 cagaaggacc aaaacactta aatatagatt tatcaagagc taaatttgaa gaattaacta
    13381 gaggtttagt tgaaaaaact atggaaccaa ctaagacagc tttacaagat gcaggacttt
    13441 ctacaggtga tatagatgat gtattattag taggtggttc tacaagaata ccagcagtac
    13501 aagaagctgt taagaagttt ataggaaaag aacctcataa aggtataaac ccagatgagt
    13561 gtgttgcagc aggtgcttct atacaagctg gagttttagc aggggatgtt aaagatttat
    13621 tattactaga tgttactcca ttatctcttg gtatagaaac tatgggtaat gtaatgacta
    13681 agataataga aagaaatact acaataccaa ctaagaagtc tcaaatattc tcaactgctg
    13741 ctgataacca aacagctgtt gatatacatg ttcttcaagg tgaaagaagt atggcttatg
    13801 acaatacaac tttaggaaga ttccaattaa cagatatacc accagcacaa agaggaatac
    13861 ctcaaataga agttactttt gatatagatg caaatggtat agttaatgtt tcagctaaag
    13921 atttaggtac aggaaaagag caaaaaataa ctataacatc aaacactaat ttatcagaag
    13981 cagaaataga gcaaaagata aaagaagcag aaatgaatgc agaagctgac aaacaaaaga
    14041 aagaaaaaat agaagcattc aatcaagctg aatctactat atatcaaact gaaaaaactt
    14101 taaatgaact tggagataaa ataagttcag gtgaaaaaga ggatatagaa aaagctatag
    14161 cagacttaaa agctgtaaaa gataatcaag atgctacagc agaagaactt aagaaagcta
    14221 cagatgaagt aatgactaag ttccaaaaag tatctcaaga aatgtaccaa aaagcagctc
    14281 aagaacaaca agcggcacaa ggtgcagaac aagcacaaga caatggacct aaagatgaca
    14341 atgtagtaga tgctgacttt aaagaagtag atgaagataa ataagctata taatatgtaa
    14401 cactaaatga taattggaac atatatgatt tgtgaaaatc atatagatgt taaagatata
    14461 tggacaatac acatcataaa gaatataata tatcatagat tatataactt aaagtagaat
    14521 ataagaatta atgatagctt gtagtttatt attctacaag ctatcgtttt gtaaaatgaa
    14581 ggtggtgtca atttttgagt acaaaaaggg attattatga agtcttaggt atcagtaaag
    14641 atgcagaagc tcaagagata aaaaaagctt atagaaaatt agcaatgaag taccatccag
    14701 atagaaatcc tggagataaa gaggcggaag aaaaatttaa agagataaat gaagcttatg
    14761 aagttctatc tgatgataca aagagaaaaa cttatgacca gtttggacat gatggattaa
    14821 atggtcaagg tggttttggt ggtcaaggag gatttggcgg tcaaggcttt ggtggttttg
    14881 aagatatgtt cggagatata tttggtgaca tgtttggagg aagcttcgga ggtggaagag
    14941 caagaagaag agggcctcaa cgtggtgcag atataagaca gagtgttact atatcttttg
    15001 aagaagctgc atttggtaaa aagatgtcta taaaagtaaa tagaagtgaa gagtgtgaag
    15061 aatgtaatgg aactggagca aaaccaggaa catcaaagaa aacttgttca acttgtaatg
    15121 gaactggcca agttagaact gttcaaagaa ctccatttgg taatatagca agttcaagac
    15181 catgtagtgc ctgtaatgga actggagaag tgattgaatc tccatgtagt aaatgtcatg
    15241 gaactggaaa tacaagaaaa gttaagacta tagaagtaga tatacctgct ggtatagatg
    15301 atggtcaaat gataaaactt tctggtcaag gtgaagtagg agaaaaaggt gctccaagag
    15361 gagacttata tattgtagtt aatgttaagt cacatccact atttactaga gatggaaatg
    15421 atatttattt tgaaatgcca attacatttg ttcaagcaac tttaggtgat gagatagaag
    15481 tacctacttt ggatggaaaa gttaaatata gtgtgccaga ggggacacaa actggaactg
    15541 tatttagact taaagagaaa ggaatcccta gaattagagg taattcaaga ggagaccaat
    15601 atgttaaggt tgtagttgaa attcctaaaa aattaaacga taagcaaaaa gaactattga
    15661 gagaatttgc gaaggagtgt gggtcgaacg tccacgaaaa gaagaaaacc ttcggacaaa
    15721 agatagaaga tatgtttaag aaaaagtagt taaagtagcc aatatataat catatttttg
    15781 aaatcttagt tatttataag attgtcaaag gagatattat gatttttata ttggctattt
    15841 ttgtataaaa aataaatgtg cataaaataa aactgaatat aaataatttt ctgaaaaata
    15901 cttgtcctaa aatatataat gtgctataat ataatcaaat aaaagaaagg ggtgattcca
    15961 gtgggaacgg atgtggcact gccaaatgat gaagaaaact ttattgtaat atacaaaata
    16021 aaattagata cttttagtgc tagattaagt actggaaaaa ctcatgagct gggataatta
    16081 ttgtaattac ctagactcaa acttttagta gtaaaatagt aatattatat agacaaggta
    16141 tctaattttt aaatcttttg tatgagttaa aatttttata aagggtatat ctgattagaa
    16201 tgtaattagg gaaacctagt tgtgaattac ttttagtata tacatgtgta aagaaatatg
    16261 tatatggtat tggttattgt gctagatgtg tatgtaaagg aatatgtgtc tagttgggta
    16321 tatgtaaaga aatatactta taatctatga aaaattttta gtataaattg ctaaaacatt
    16381 gagattgttt tttatagaaa gttagtttat accaactaaa aatgtgctta agatttgttt
    16441 gatgtttaat tataaataag gttgtagata aaaaaataag taaagacaaa ggtttaaaat
    16501 acttgcttta aatatagttt gttttgaaca cttgccaaat taaaataatt aataaaatag
    16561 acatcttctc atagtaaaat atactgtgag aggatgtttt tgctttgttc ataaactttt
    16621 atgaaaaatt tgcatagtgt cacattttaa tatactatat atataataaa atatagataa
    16681 aattaaatga ttcaaaagag aaaggtgaaa agagatgtat tatataggtg tagacatagg
    16741 aggaacaggt atacaagcag gagtagttga taactatggg aagataattt ttaggtcaga
    16801 gtgtaaaaca gtaattgaaa aaggctttga aggaatactt aatgacataa aaataatgat
    16861 ttataagttg ttggaagata ataaacttac tatgagtgac ataaaatcta ttggatttgg
    16921 tgttccaggt tttataaata aagaaggatt agtaacttgt gtaaatttaa aatggaataa
    16981 aaaagctttt aataaagagt taaaaagaag atttccagat gctgaaattc atggagaaaa
    17041 tgatgcaaca gtagcagcac ttggagaagc aaagtttgga agtatgaaag gtgctaatgt
    17101 tggagtatta tatactttag gaactggtgt aggtggagga atagtaatta atcaaaaagt
    17161 cttttctgga gcacatggat tgggttcaga aataggtcat caaattatag gagaaaacta
    17221 ttttaattgt aattgtggaa ataatggttg tgtagaaact ttttgttcag caactgcaat
    17281 tataaagtat tctcaaaaac tgatagaaga aggagaaaag agtaggattt tagatttggc
    17341 agagggaaat ttagaaaatg taaatgcaaa gatggtgttt gatgcatata gagaaaatga
    17401 tttagtggca attaaagtaa taaatagatt taaagattat ttagcaaaaa cttttgcaaa
    17461 cacaataaat tctttagacc cagaaattat atctatagga ggaggcattt ctaaatctag
    17521 cgatataata cttgatggaa tagaagattt ggtaagaaaa tttgtattat acaaaacaga
    17581 agatatagct acaattacat gtgcaacttt aggttcagac gcaggaatta taggagcagc
    17641 ttttttataa tgtaaatgaa ctgcttattg gaggcgtgat gatatatggg taaaacaaat
    17701 gctagaagaa cgcttttttt gatagcaata ggttcaggaa ctatgctgaa tcctcttaat
    17761 tcttctatga tttcacttgc tttacatagt atacaaaatg attttcatat tagttttaca
    17821 actgtatctt ggattgtttc agcattttac ctagctagtg ctattgcaca accagtttca
    17881 ggtaagatag gagatttaat aggtagaaag gtcttatttt tgagtggttt gatgcttgta
    17941 attttatcag catccatagt accacttgtt caatcattct ttatattgat ttttataaga
    18001 gtaattcaag caattggaac aagtacccta tatccatctg gagttgctct tatacaaaat
    18061 aatataaaag aaagacaatc ttctgcatta gcagttctaa ccatttttgc ttcaactaca
    18121 gcaggattag gtccgacact tggaggatta ttgttggact taggaggatg gcatgctata
    18181 tttcttgtaa atatacctgt tgttttggtt tctatatgct tagggtattt tttattccca
    18241 aaagaagtaa aagaaaagaa atctataaaa gaaactttaa aaaatgtttt gtcaagatta
    18301 gatattattg gcatacttct attttcaatt gcaatgattt ttatattact atttttgcta
    18361 tctatgaagg aatcttttaa cttagaacaa cttgtatttg gtataatact gatgtgtctt
    18421 tttatttggc atgaattgag aacaaaattg ccatttatag atattaagct ttttgtaagt
    18481 aatcctaaat tgtcaaaagt ttacttgcaa tttattatat taaatttctt taattatatt
    18541 ttgttttttg gtcttcctag ttattttcaa gatgccttac attatagtgc aaagtcgact
    18601 ggattattta tgctatttat gtctggtata ggtatattta tatctccatt aactggaaaa
    18661 tggatagata aatctggaac tagatttcct cttgttacat catcaatctt tatgtttatt
    18721 agtgcagtac ttctttcagt agtttttatc catatacctg taataggaaa gggtattata
    18781 ttatcattag caggtattag ttatggagtt ggtaatgtag ccctgcaatc ctctatgttt
    18841 gaagaaagtc ctcgtgacag tatagggaca gcttctggtc tgtttcaaac tagtcgttat
    18901 ttaggttcta ttttagcaac tgttttactt ggaatggtat ttgaaggaaa tataacatca
    18961 gaacaatttc agatattagg ttatgttatg gtggtcttag gtacaataag ttttttatta
    19021 aattttatat taaagaaaga attaagaaaa gtagaatagt ggatttatgg atttaataag
    19081 tctaataact gataagttta aaaatattgt ttgtaaaaca taactggttt gatatttatt
    19141 aattctaagt tttgaagcat agagtactcg ataagtatac aatattttga attaaaatta
    19201 agcagaaatt tgaactagtc tttcaaatct ctgcttaatt tagtagttaa atttttttat
    19261 agagaaaata agatttgaca cttagataaa aaatcattgc attttcaaaa ttctttaaat
    19321 caaacccaag tatctcatta atcttttcca atctatatac tagcgtgttt ctatgtaaaa
    19381 acatactagt agatgtctta gaaatattta aatcattatt tataaatttt attcctgtat
    19441 atagaagttc ttcgtcaata gatttaatct tattaaaatc tattaattta ttgagtatat
    19501 tatcctcatt aattaaatct aaagttttat atctaataag gtcaaacaaa tttaaaaact
    19561 tattttcagc attgtctttt ataatatgag gtagtaaatc agaacataac tgtaatctaa
    19621 aataaaaatc agctttacta tctaattcac caagataaaa aatataagta ctttgataag
    19681 tttcagtttc aattatattt tgtgtagtta cattaatatc taaattatat ttagaattta
    19741 ctataaaaaa accattgtgt tgtattatat ttatatcttc aaataaatta taaaaaatat
    19801 tttttaggta ttcaaagtct atatgagatt ggtaaattaa ataaaagttg ccttttaaat
    19861 tatcaagatt atttttatct agaaaatcaa taacataaat agcattattg aaagtaacta
    19921 aatggctact agcatctaac ttttggtttt catagggata gatatttatt tttttattaa
    19981 gctgtctttc taaaaaatct tttaactctt ccataaagtc tccttaaaaa taagattata
    20041 ttcttatctt atagctaaag tagtttcttt gtcaaatatg tgtactctac tattgtcaac
    20101 tgaaagtgtt aagtcatcac caacattaat tctgttttta ctgtcaaatc taattgttat
    20161 cgtattttcg cctagtttta agtgagcata agtttctgct cccataagtt cttttatttc
    20221 aattcttgat ttaaaacaag tatctggatt agatttaata aaagtatctt ctacatgaat
    20281 atcttctggt ctgataccta taacaacttc attattaata taattgtctt ttattaaatc
    20341 atagtgtttt tctttattca atttaagctt aatatgttca ttttgtgcat aaattttatc
    20401 attttcttct attaatatta catcaataaa attcatctgt ggtgctccaa taaatcctgc
    20461 aacaaatata ttagctggat aatcgtatac atcttgtgga gttgcaatct gctgaactac
    20521 tccatccttc attactacga ttctatcagc catagtcata gcttcaactt ggtcgtgtgt
    20581 tacatagata aatgtagttc caagctgttg gtgtagctta gttatctctg ttctcatagc
    20641 agttctaagt tttgcatcta agttggatag aggttcatcc attaagaata ccttaggatt
    20701 tctaactatt gcacgtccta aggcaaccct ttgtctttgt cctccagata atgttttagg
    20761 ttttttattt aaaagaggta gtaagtctaa tattttagca gcttctttaa cttttttgtc
    20821 tatttcatct ttaggcaatt ttctaagttt aagtgcaaat gccatgtttt cgtaaacaga
    20881 taagtgggga tataaagcat agttttgaaa aaccatagct atatctctat cttttggttc
    20941 tatatcattg acaagtttat ctccaatgta tagttctcct tcagagattt cttcaagacc
    21001 agcaatcatt ctaagtgtag tcgatttacc acaaccagat ggtcctacta aaacgataaa
    21061 ttctttatct ttaatgtcta tatttatatt ttttactgcg ttaaatccat ttgagtaaag
    21121 ttttgatata ttttttaaaa ttacttctga cataatattc tccttgatat ttaaatttta
    21181 atgatatagt atcaaatttt tttattatat taaatgtgta aaatgactaa atgtatttgt
    21241 ttaatatgta tatttaattt ttagcaaaga ataaaactaa cagtaaaata tatttaaaaa
    21301 attaaaaaac aaaattaaat ttattatcaa aaaat
//
LOCUS       DAMJYN010000067        20643 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.069, whole genome shotgun sequence.
ACCESSION   DAMJYN010000067 DAMJYN010000000
VERSION     DAMJYN010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20643)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20643)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20643
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.069"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            121..675
                     /gene="tcdR"
                     /locus_tag="PC466_002696"
     CDS             121..675
                     /gene="tcdR"
                     /locus_tag="PC466_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin sigma factor TcdR"
                     /protein_id="HDF2770063.1"
                     /translation="MQKSFYELIVLARNNSVDDLQEILFMFKPLVKKLSRVLHYEEGE
                     TDLIIFFIELIKNIKLSSFSEKSDAIIVKYIHKSLLNKTFELSRRYSKMKFNFVEFDE
                     NILNMKNNYQSKSVFEEDICFFEYILKELSGIQRKVIFYKYLKGYSDREISVKLKISR
                     QAVNKAKNRAFKKIKKDYENYFNL"
     gene            1006..8106
                     /gene="tcdB"
                     /locus_tag="PC466_002697"
                     /gene_synonym="toxB"
     CDS             1006..8106
                     /gene="tcdB"
                     /locus_tag="PC466_002697"
                     /gene_synonym="toxB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin TcdB"
                     /protein_id="HDF2770064.1"
                     /translation="MSLVNRKQLEKMANVRFRVQEDEYVAILDALEEYHNMSENTVVE
                     KYLKLKDINSLTDIYIDTYKKSGRNKALKKFKEYLVTEVLELKNNNLTPVEKNLHFVW
                     IGGQINDTAINYINQWKDVNSDYNVNVFYDSNAFLINTLKKTIVESATNDTLESFREN
                     LNDPRFDYNKFYRKRMEIIYDKQKNFINYYKTQREENPDLIIDDIVKIYLSNEYSKDI
                     DELNSYIEESLNKVTENSGNDVRNFEEFKGGESFKLYEQELVERWNLAAASDILRISA
                     LKEVGGVYLDVDMLPGIQPDLFESIEKPSSVTVDFWEMVKLEAIMKYKEYIPGYTSEH
                     FDMLDEEVQSSFESVLASKSDKSEIFSSLGDMEASPLEVKIAFNSKGIINQGLISVKD
                     SYCSNLIVKQIENRYKILNNSLNPAISEDNDFNTTTNAFIDSIMAEANADNGRFMMEL
                     GKYLRVGFFPDVKTTINLSGPEAYAAAYQDLLMFKEGSMNIHLIEADLRNFEISKTNI
                     SQSTEQEMASLWSFDDARAKAQFEEYKKNYFEGSLGEDDNLDFSQNTVVDKEYLLEKI
                     SSLARSSERGYIHYIVQLQGDKISYEAACNLFAKTPYDSVLFQKNIEDSEIAYYYNPG
                     DGEIQEIDKYKIPSIISDRPKIKLTFIGHGKDEFNTDIFAGLDVDSLSTEIETAIDLA
                     KEDISPKSIEINLLGCNMFSYSVNVEETYPGKLLLRVKDKVSELMPSISQDSIIVSAN
                     QYEVRINSEGRRELLDHSGEWINKEESIIKDISSKEYISFNPKENKIIVKSKNLPELS
                     TLLQEIRNNSNSSDIELEEKVMLAECEINVISNIDTQVVEGRIEEAKSLTSDSINYIK
                     NEFKLIESISDALYDLKQQNELEESHFISFEDILETDEGFSIRFIDKETGESIFVETE
                     KAIFSEYANHITEEISKIKGTIFDTVNGKLVKKVNLDATHEVNTLNAAFFIQSLIEYN
                     SSKESLSNLSVAMKVQVYAQLFSTGLNTITDAAKVVELVSTALDETIDLLPTLSEGLP
                     VIATIIDGVSLGAAIKELSETSDPLLRQEIEAKIGIMAVNLTAATTAIITSSLGIASG
                     FSILLVPLAGISAGIPSLVNNELILRDKATKVVDYFSHISLAESEGAFTSLDDKIMMP
                     QDDLVISEIDFNNNSITLGKCEIWRMEGGSGHTVTDDIDHFFSAPSITYREPHLSIYD
                     VLEVQKEELDLSKDLMVLPNAPNRVFAWETGWTPGLRSLENDGTKLLDRIRDNYEGEF
                     YWRYFAFIADALITTLKPRYEDTNIRINLDSNTRSFIVPVITTEYIREKLSYSFYGSG
                     GTYALSLSQYNMNINIELNENDTWVIDVDNVVRDVTIESDKIKKGDLIENILSKLSIE
                     DNKIILDNHEINFSGTLNGGNGFVSLTFSILEGINAVIEVDLLSKSYKVLISGELKTL
                     MANSNSVQQKIDYIGLNSELQKNIPYSFMDDKGKENGFINCSTKEGLFVSELSDVVLI
                     SKVYMDNSKPLFGYCSNDLKDVKVITKDDVIILTGYYLKDDIKISLSFTIQDENTIKL
                     NGVYLDENGVAEILKFMNKKGSTNTSDSLMSFLESMNIKSIFINSLQSNTKLILDTNF
                     IISGTTSIGQFEFICDKDNNIQPYFIKFNTLETKYTLYVGNRQNMIVEPNYDLDDSGD
                     ISSTVINFSQKYLYGIDSCVNKVIISPNIYTDEINITPIYEANNTYPEVIVLDTNYIS
                     EKINININDLSIRYVWSNDGSDFILMSTDEENKVSQVKIRFTNVFKGNTISDKISFNF
                     SDKQDVSINKVISTFTPSYYVEGLLNYDLGLISLYNEKFYINNFGMMVSGLVYINDSL
                     YYFKPPIKNLITGFTTIGDDKYYFNPDNGGAASVGETIIDGKNYYFSQNGVLQTGVFS
                     TEDGFKYFAPADTLDENLEGEAIDFTGKLTIDENVYYFGDNYRAAIEWQTLDDEVYYF
                     STDTGRAFKGLNQIGDDKFYFNSDGIMQKGFVNINDKTFYFDDSGVMKSGYTEIDGKY
                     FYFAENGEMQIGVFNTADGFKYFAHHDEDLGNEEGEALSYSGILNFNNKIYYFDDSFT
                     AVVGWKDLEDGSKYYFDEDTAEAYIGISIINDGKYYFNDSGIMQIGFVTINNEVFYFS
                     DSGIVESGMQNIDDNYFYIDENGLVQIGVFDTSDGYKYFAPANTVNDNIYGQAVEYSG
                     LVRVGEDVYYFGETYTIETGWIYDMENESDKYYFDPETKKAYKGINVIDDIKYYFDEN
                     GIMRTGLITFEDNHYYFNEDGIMQYGYLNIEDKTFYFSEDGIMQIGVFNTPDGFKYFA
                     HQNTLDENFEGESINYTGWLDLDEKRYYFTDEYIAATGSVIIDGEEYYFDPDTAQLVI
                     SE"
     gene            8228..8728
                     /gene="tcdE"
                     /locus_tag="PC466_002698"
     CDS             8228..8728
                     /gene="tcdE"
                     /locus_tag="PC466_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holin-like glycosylating toxin export protein
                     TcdE"
                     /protein_id="HDF2770065.1"
                     /translation="MHSSSPFYISNGNKIFFYINLGGVMNMTISFLSEHIFIKLVILT
                     ISFDTLLGCLSAIKSRKFNSSFGIDGGIRKVAMIACIFFLSVVDILTKFNFLFMLPQD
                     CINFLRLKHLGISEFFSILFILYESVSILKNMCLCGLPVPKRLKEKIAVLLDAMTDEM
                     NAKDEK"
     gene            8819..8968
                     /locus_tag="PC466_002699"
     CDS             8819..8968
                     /locus_tag="PC466_002699"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770066.1"
                     /translation="MKTREQMPRDTQVLNTYNFEASVHYYMDDKVVYQTLVHKDGAWS
                     VGKIY"
     gene            9057..9239
                     /locus_tag="PC466_002700"
     CDS             9057..9239
                     /locus_tag="PC466_002700"
                     /inference="COORDINATES: protein motif:HMM:NF022413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770067.1"
                     /translation="MRDEGQNDRENKYQTLINDLIDSLKVIGKIYKEIKTLKKYKICL
                     QITIRQSPYLIEESIN"
     gene            9456..17588
                     /gene="tcdA"
                     /locus_tag="PC466_002701"
                     /gene_synonym="toxA"
     CDS             9456..17588
                     /gene="tcdA"
                     /locus_tag="PC466_002701"
                     /gene_synonym="toxA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021394011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin TcdA"
                     /protein_id="HDF2770068.1"
                     /translation="MSLISKEELIKLAYSIRPRENEYKTILTNLDEYNKLTTNNNENK
                     YLQLKKLNESIDVFMNKYKNSSRNRALSNLKKDILKEVILIKNSNTSPVEKNLHFVWI
                     GGEVSDIALEYIKQWADINAEYNIKLWYDSEAFLVNTLKKAIVESSTTEALQLLEEEI
                     QNPQFDNMKFYKKRMEFIYDRQKRFINYYKSQINKPTVPTIDDIIKSHLVSEYNRDET
                     LLESYRTNSLRKINSNHGIDIRANSLFTEQELLNIYSQELLNRGNLAAASDIVRLLAL
                     KNFGGVYLDVDMLPGIHSDLFKTIPRPSSIGLDRWEMIKLEAIMKYKKYINNYTSENF
                     DKLDQQLKDNFKLIIESKSEKSEIFSKLENLNVSDLEIKIAFALGSVINQALISKQGS
                     YLTNLVIEQVKNRYQFLNQHLNPAIESDNNFTDTTKIFHDSLFNSATAENSMFLTKIA
                     PYLQVGFMPEARSTISLSGPGAYASAYYDFINLQENTIEKTLKASDLIEFKFPENNLS
                     QLTEQEINSLWSFDQASAKYQFEKYVRDYTGGSLSEDNGVDFNKNTALDKNYLLNNKI
                     PSNNVEEAGSKNYVHYIIQLQGDDISYEATCNLFSKNPKNSIIIQRNMNESAKSYFLS
                     DDGESILELNKYRIPERLKNKEKVKVTFIGHGKDEFNTSEFARLSVDSLSNEISSFLD
                     TIKLDISPKNVEVNLLGCNMFSYDFNVEETYPGKLLLSIMDKITSTLPDVNKDSITIG
                     ANQYEVRINSEGRKELLAHSGKWINKEEAIMSDLSSKEYIFFDSIDNKLKAKSKNIPG
                     LASISEDIKTLLLDASVSPDTKFILNNLKLNIESSIGDYIYYEKLEPVKNIIHNSIDD
                     LIDEFNLLENVSDELYELKKLNNLDEKYLISFEDISKNNSTYSVRFINKSNGESVYVE
                     TEKEIFSKYSEHITKEISTIKNSIITDVNGNLLDNIQLDHTSQVNTLNAAFFIQSLID
                     YSSNKDVLNDLSTSVKVQLYAQLFSTGLNTIYDSIQLVNLISNAVNDTINVLPTITEG
                     IPIVSTILDGINLGAAIKELLDEHDPLLKKELEAKVGVLAINMSLSIAATVASIVGIG
                     AEVTIFLLPIAGISAGIPSLVNNELILHDKATSVVNYFNHLSESKEYGPLKTEDDKIL
                     VPIDDLVISEIDFNNNSIKLGTCNILAMEGGSGHTVTGNIDHFFSSPYISSHIPSLSV
                     YSAIGIKTENLDFSKKIMMLPNAPSRVFWWETGAVPGLRSLENNGTKLLDSIRDLYPG
                     KFYWRFYAFFDYAITTLKPVYEDTNTKIKLDKDTRNFIMPTITTDEIRNKLSYSFDGA
                     GGTYSLLLSSYPISMNINLSKDDLWIFNIDNEVREISIENGTIKKGNLIEDVLSKIDI
                     NKNKLIIGNQTIDFSGDIDNKDRYIFLTCELDDKISLIIEINLVAKSYSLLLSGDKNY
                     LISNLSNTIEKINTLGLDSKNIAYNYTDESNNKYFGAISKTSQKSIIHYKKDSKNILE
                     FYNGSTLEFNSKDFIAEDINVFMKDDINTITGKYYVDNNTDKSIDFSISLVSKNQVKV
                     NGLYLNESVYSSYLDFVKNSDGHHNTSNFMNLFLNNISFWKLFGFENINFVIDKYFTL
                     VGKTNLGYVEFICDNNKNIDIYFGEWKTSSSKSTIFSGNGRNVVVEPIYNPDTGEDIS
                     TSLDFSYEPLYGIDRYINKVLIAPDLYTSLININTNYYSNEYYPEIIVLNPNTFHKKV
                     NINLDSSSFEYKWSTEGSDFILVRYLEESNKKILQKIRIKGILSNTQSFNKMSIDFKD
                     IKKLSLGYIMSNFKSFNSENELDRDHLGFKIIDNKTYYYDEDSKLVKGLININNSLFY
                     FDPIESNLVTGWQTINGKKYYFDINTGAASTSYKIINGKHFYFNNNGVMQLGVFKGPD
                     GFEYFAPANTQNNNIEGQAIVYQSKFLTLNGKKYYFDNDSKAVTGWRIINNEKYYFNP
                     NNAIAAVGLQVIDNNKYYFNPDTAIISKGWQTVNGSRYYFDTDTAIAFNGYKTIDGKH
                     FYFDSDCVVKIGVFSGSNGFEYFAPANTYNNNIEGQAIVYQSKFLTLNGKKYYFDNNS
                     KAVTGWQTIDSKKYYFNTNTAEAATGWQTIDGKKYYFNTNTAEAATGWQTIDGKKYYF
                     NTNTSIASTGYTIINGKYFYFNTDGIMQIGVFKVPNGFEYFAPANTHNNNIEGQAILY
                     QNKFLTLNGKKYYFGSDSKAITGWQTIDGKKYYFNPNNAIAATHLCTINNDKYYFSYD
                     GILQNGYITIERNNFYFDANNESKMVTGVFKGPNGFEYFAPANTHNNNIEGQAIVYQN
                     KFLTLNGKKYYFDNDSKAVTGWQTIDSKKYYFNLNTAVAVTGWQTIDGEKYYFNLNTA
                     EAATGWQTIDGKRYYFNTNTYIASTGYTIINGKHFYFNTDGIMQIGVFKGPDGFEYFA
                     PANTHNNNIEGQAILYQNKFLTLNGKKYYFGSDSKAVTGLRTIDGKKYYFNTNTAVAV
                     TGWQTINGKKYYFNTNTYIASTGYTIISGKHFYFNTDGIMQIGVFKGPDGFEYFAPAN
                     TDANNIEGQAIRYQNRFLYLHDNIYYFGNDSKAATGWATIDGNRYYFEPNTAMGANGY
                     KTIDNKNFYFRNGLPQIGVFKGPNGFEYFAPANTDANNIDGQAIRYQNRFLHLLGKIY
                     YFGNNSKAVTGWQTINSKVYYFMPDTAMAAAGGLFEIDGVIYFFGVDGVKAPGIYG"
     gene            complement(17923..18483)
                     /locus_tag="PC466_002702"
     CDS             complement(17923..18483)
                     /locus_tag="PC466_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin regulator"
                     /protein_id="HDF2770069.1"
                     /translation="MFFGNISSPACSEDHEEVISNQTSVIDSQKTEIETLNSKLSDAE
                     PWFKMKDDEKKAIEAENQRKAEEAKKAEEQRKKEEEEKKGYDTGITYDQLARTPDDYK
                     YKKVKFEGKVIQVIEDGDEVQIRLAVSGNYDKVVLCSYKKSITPSRVLEDDYITIRGI
                     SAGTITYESTMGGKITIPGIAVEKIN"
     gene            19020..19265
                     /locus_tag="PC466_002703"
     CDS             19020..19265
                     /locus_tag="PC466_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pathogenicity locus"
                     /protein_id="HDF2770070.1"
                     /translation="MGELQKIPGVGKATEKSLIMLGYTTIKSLKDANPAQMYEKECLM
                     RGQHIDRCQLYVYRCAVYFASTENPEPEKLKWWYWKD"
     gene            complement(19482..19751)
                     /locus_tag="PC466_002704"
     CDS             complement(19482..19751)
                     /locus_tag="PC466_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HDF2770071.1"
                     /translation="MFESRCGVCCDSCTKKEQVNCTGCPTMEKPFWGGECKVKTCCES
                     KELNHCGECDTFPCDMLLNKGKDQGFDPMVNIGQCRKWLEETVSN"
     gene            complement(19963..20265)
                     /locus_tag="PC466_002705"
     CDS             complement(19963..20265)
                     /locus_tag="PC466_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770072.1"
                     /translation="MKYSKGFKLIYSLVEYSKKFKVIYSVMKYSKGFKLIYSLVEYSK
                     RFKLIYDVMKYSKEFKLIYSLVEYSKRFKVIYSVMKYSKRFKAIYNAVKYIQGDLK"
BASE COUNT         8177 a         2360 c         3100 g         7006 t
ORIGIN      
        1 gtattttcat ataaaattta atttatttgc cgattatata attataatga ctgatttaat
       61 tccaatgttg tcaaaatttt taaataaatc atcattataa atataagaga ggatgatttt
      121 atgcaaaagt ctttttatga attaattgtt ttagcaagaa ataactcagt agatgatttg
      181 caagaaattt tatttatgtt taagccatta gtaaaaaaac ttagtagagt tttacattat
      241 gaagagggag aaacagattt aataatattt tttattgaat taataaaaaa tattaaatta
      301 agtagctttt cagaaaaaag cgatgctatt atagtcaaat atattcataa atcattactg
      361 aataagactt ttgagttgtc tagaagatat tctaaaatga agtttaattt tgtagaattt
      421 gatgaaaata tcttaaatat gaaaaataat tatcaaagta agtctgtttt tgaggaagat
      481 atttgttttt tcgaatatat tttgaaagaa ttatctggta ttcaaagaaa agttattttt
      541 tataaatatt taaaaggata ttctgataga gaaatatcag tgaaattaaa aatatctaga
      601 caagctgtta ataaggctaa aaatagagca tttaaaaaaa taaaaaaaga ctatgaaaat
      661 tattttaact tgtaattaat gaatttaaag aaatatttac aatagaaatc aaattttaga
      721 attaacttta ttgtaaaatc aataacttaa tctaagaata tcttaatttt tatattttat
      781 atagaacaaa gtttacatat ttatttcaga caacgtcttt attcaatcga agagcaaatt
      841 aatcaactga gtgtcttcaa tttaaaatgt taggaagtga atgtatatga aaacctaagt
      901 agatattagt atattttata aatagaaagg aggatatata aaagagtttt agcatttaga
      961 tgtaaaaata ttcaataaaa atattatagt aaaggagaaa attttatgag tttagttaat
     1021 agaaaacagt tagaaaaaat ggcaaatgta agatttcgtg ttcaggaaga tgaatatgta
     1081 gcaatattgg atgctttaga agaatatcat aatatgtcag agaatactgt agtcgaaaaa
     1141 tatttaaaat taaaagatat aaatagttta acagatattt atatagatac atataaaaag
     1201 tctggtagaa ataaagcctt aaaaaaattt aaggaatacc tagttacaga agtattagag
     1261 ctaaagaata ataatttaac tccagttgag aaaaatttac attttgtttg gattggaggt
     1321 caaataaatg acactgctat taattatata aatcaatgga aagatgtaaa tagtgattat
     1381 aatgttaatg ttttttatga tagtaatgca tttttgataa acacattgaa aaaaactata
     1441 gtagaatcag caacaaatga tacacttgaa tcatttagag aaaacttaaa tgaccctaga
     1501 tttgactata ataaatttta cagaaaacgt atggagataa tctatgataa gcagaaaaat
     1561 ttcataaatt actataaaac tcaaagagaa gaaaatcctg accttataat tgatgatatt
     1621 gtaaagatat atctttcaaa cgagtattca aaggatatag atgaacttaa ttcctatatt
     1681 gaagagtcat taaataaagt tacagaaaat agtgggaatg atgttagaaa ctttgaagaa
     1741 tttaaaggtg gagagtcatt caaattatat gaacaagagt tggtagaaag atggaatttg
     1801 gcagctgctt ctgacatatt aagaatatct gccttaaaag aagttggtgg tgtatattta
     1861 gatgttgata tgttaccagg aatacaacca gacctatttg agtctataga gaaacctagt
     1921 tcagtaacag tggatttttg ggaaatggta aaattagaag ctataatgaa atacaaagaa
     1981 tacataccag gatatacttc agagcatttt gatatgttgg atgaagaagt tcaaagtagt
     2041 tttgaatctg ttctagcttc taagtcagat aagtcagaaa tattctcatc acttggcgat
     2101 atggaggcat caccactaga agttaaaatt gcatttaata gtaaaggtat tataaatcaa
     2161 ggactaattt ctgtgaaaga ctcatattgt agcaatttaa tagtaaaaca aatcgagaac
     2221 agatataaga tattgaataa tagtttaaat ccagctatta gcgaggataa cgatttcaat
     2281 actacaacga atgcttttat tgatagtata atggctgaag ctaatgcaga taatggtaga
     2341 tttatgatgg aactaggaaa gtatttaaga gttggtttct tcccagatgt taaaactact
     2401 attaacttaa gtggccctga agcatatgcg gcagcttatc aagatttatt aatgtttaaa
     2461 gaaggtagta tgaatatcca tttgatagaa gctgacttaa gaaactttga aatctctaaa
     2521 actaatattt ctcaatcaac tgaacaagaa atggctagct tatggtcatt tgacgatgca
     2581 agagctaaag ctcaatttga agaatacaaa aaaaattact ttgaaggttc tcttggagaa
     2641 gatgacaatc ttgacttttc tcaaaataca gtagttgaca aggagtatct tttagaaaaa
     2701 atatcttcat tagcaagaag ttcagagaga ggatatatac actatattgt tcagttacaa
     2761 ggagataaaa ttagttatga agcagcatgt aacttatttg caaagactcc ttatgatagt
     2821 gtactgtttc agaaaaatat agaagattca gaaattgcat attattataa tcctggagat
     2881 ggtgaaatac aagaaataga caagtataaa attccaagta taatttctga tagacctaag
     2941 attaaattaa catttattgg tcatggtaaa gatgaattta atactgatat atttgcaggt
     3001 cttgatgtag attcattatc cacagaaata gaaacagcaa tagatttagc taaagaggat
     3061 atttctccta agtcaataga aataaactta ctgggatgta acatgtttag ctattctgta
     3121 aatgtagagg agacttatcc tgggaaatta ttacttagag ttaaagataa agtatcagaa
     3181 ttaatgccat ctataagtca agactctatt atagtaagtg caaatcaata tgaagttaga
     3241 ataaatagtg aaggaagaag agaattattg gatcattctg gtgaatggat aaataaagaa
     3301 gaaagtatta taaaggatat ttcatcaaaa gaatatatat catttaatcc taaagaaaat
     3361 aaaattatag taaaatctaa aaatttacct gaattatcta cattattaca agaaattaga
     3421 aacaattcta attcaagtga tattgaacta gaagaaaaag taatgttagc agaatgtgag
     3481 ataaatgtta tttcaaatat agatacacaa gtggtagaag gaaggattga agaagctaaa
     3541 agcttaactt ctgactctat taattatata aagaatgaat ttaaactaat agaatctatt
     3601 tctgatgcac tatacgattt aaaacaacag aatgaattag aagagtctca ttttatatct
     3661 tttgaggata tattggagac tgatgaaggc tttagtataa gatttattga taaagaaact
     3721 ggagaatcta tatttgtaga aactgaaaag gcaatattct ctgaatatgc taatcatata
     3781 actgaagaga tttctaagat aaaaggtact atatttgata ctgtaaatgg taagttagta
     3841 aaaaaagtaa atttagatgc tacacatgaa gtgaatactt taaatgctgc attttttata
     3901 caatcattaa tagaatataa tagttctaaa gaatctctta gtaatttaag tgtagcaatg
     3961 aaagttcaag tttatgctca attatttagt actggtttaa atactattac agatgcagcc
     4021 aaagttgttg aattagtatc aactgcatta gatgaaacta tagatttact tcctacatta
     4081 tctgaaggat tacctgtaat tgcaactatc atagatggtg taagtttagg tgcagcaatc
     4141 aaagagctaa gtgaaacaag tgacccatta ttaagacaag aaatagaagc taagataggt
     4201 ataatggcag taaatttaac agcagctaca actgcaatca ttacttcatc tttaggaata
     4261 gctagtggat ttagtatact tttagttcct ttagcaggaa tttcagcagg tataccaagt
     4321 ttagtaaaca atgagcttat cctaagagat aaagcaacaa aagttgtaga ttattttagt
     4381 catatatcat tagctgagtc tgaaggagca tttacttcat tagatgataa aataatgatg
     4441 ccacaagatg atttagtaat atctgagata gactttaata acaattcaat aactttaggt
     4501 aaatgtgaaa tctggagaat ggaaggtggc tcaggtcata ctgtaactga tgatatagat
     4561 cacttctttt cagcaccatc aataacatat agagagccac acttatctat atatgacgta
     4621 ttggaagtac aaaaagaaga acttgatttg tcaaaagatt taatggtatt acctaatgct
     4681 ccaaatagag tatttgcttg ggaaacagga tggacaccag gtttaagaag cttagaaaat
     4741 gatggcacaa aactgttaga ccgtataaga gataactatg aaggtgagtt ttattggaga
     4801 tattttgctt ttatagctga tgctttaata acaacattaa aaccaagata tgaagatact
     4861 aatataagaa taaatttaga tagtaatact agaagcttta tagtcccagt gataactaca
     4921 gaatatataa gagagaaatt atcatattct ttttatggtt ctggaggaac ttatgcatta
     4981 tctctttctc aatacaatat gaatataaac atagaattaa atgaaaatga tacttgggtt
     5041 atagatgtcg acaatgtcgt aagagatgtc actatagaat ctgataaaat taaaaaagga
     5101 gatttaatag agaatatttt atctaaatta agtattgaag acaataaaat tattttagat
     5161 aatcatgaaa ttaatttctc tggaacatta aatggaggta atggatttgt atctttaaca
     5221 ttctcaatct tagaaggaat aaatgcagtt atagaagttg atttattatc taaatcatat
     5281 aaagttctta tttctggtga actaaaaaca ttgatggcaa attcaaattc tgttcaacag
     5341 aaaatagatt atataggatt gaacagcgaa ttacaaaaaa atatacctta tagttttatg
     5401 gatgataaag gaaaagaaaa tggatttatt aattgttcta caaaagaagg tttatttgta
     5461 tctgaattat ctgatgtagt tcttataagt aaagtttata tggacaatag taaacctcta
     5521 tttggatatt gtagtaatga tttgaaagat gttaaagtca taactaaaga tgacgttatt
     5581 atattaacag gatattattt aaaagatgat ataaaaatct ctctttcttt tactatacaa
     5641 gatgaaaata ctataaaatt aaatggagta tatttagatg aaaatggagt agctgaaata
     5701 ttgaaattta tgaataaaaa aggtagtaca aatacttcag attctttaat gagcttttta
     5761 gaaagtatga atataaaaag tattttcata aattccttac aatctaatac taagcttata
     5821 ttagatacta attttataat aagtggtact acttctattg gtcaatttga gtttatttgt
     5881 gataaagata ataatataca accatatttc attaagttta atacactaga aactaaatat
     5941 actctatatg taggtaatag acaaaatatg atagtagaac caaattatga tttagatgat
     6001 tctggagata tatcttcaac tgtcattaat ttttctcaga aataccttta tggaatagac
     6061 agttgtgtta ataaagttat aatttcgcca aatatatata cagatgaaat aaacataaca
     6121 cctatatatg aagcaaataa tacttatcca gaagtgattg tattagatac aaattatata
     6181 agtgaaaaaa tcaatattaa tatcaatgat ttatctatac gatatgtatg gagtaatgat
     6241 ggaagtgatt ttattcttat gtcaactgat gaagagaaca aggtatcaca agttaaaata
     6301 agatttacta atgtttttaa aggtaatact atatcagata agatatcttt taattttagt
     6361 gataagcaag atgtatctat aaataaagtt atttcaacat ttacaccttc atattatgtg
     6421 gaaggattac ttaattatga tttaggtctg atttctttat acaatgagaa attttatatt
     6481 aataactttg gaatgatggt gtctggatta gtatatatta atgattcatt atattatttc
     6541 aagccaccaa taaagaactt gataactgga tttacaacta taggtgatga taaatactac
     6601 tttaatccag ataatggtgg agctgcttca gtcggagaaa caataattga tggcaaaaac
     6661 tactacttca gccaaaatgg agtgttacaa acaggtgtat ttagtacaga agatggattt
     6721 aaatattttg ctccagcaga tacacttgat gaaaatctag agggggaagc aattgatttt
     6781 actggcaaac taactattga tgaaaatgtt tattattttg gagataatta tagagcagct
     6841 atagaatggc aaacattaga tgatgaagtg tactatttta gtacagatac aggtagagct
     6901 tttaaagggc taaatcaaat aggtgatgat aaattctatt tcaactctga tggtattatg
     6961 caaaaaggat ttgttaatat aaatgataag acattctatt ttgatgattc tggtgtgatg
     7021 aagtcaggat atactgaaat agatggaaaa tatttttact ttgctgagaa tggagaaatg
     7081 caaataggag tatttaatac agcagatgga tttaaatatt ttgctcatca tgatgaagat
     7141 ttaggaaatg aagaaggtga agcactttca tattctggta tacttaattt taacaataag
     7201 atttattatt ttgatgattc atttacagca gtagttggat ggaaggattt agaagatggt
     7261 tcaaaatatt actttgatga agatacagca gaagcatata taggtatctc aataattaat
     7321 gatggtaaat attattttaa tgattctgga atcatgcaaa ttggatttgt cacaataaat
     7381 aatgaagtat tttatttctc tgattctgga atagtagaat ctggaatgca aaatatagat
     7441 gataattatt tctatataga cgaaaatggt ctagttcaaa ttggtgtatt tgacacttca
     7501 gatggatata aatactttgc accagctaat actgtaaatg ataatatcta tggacaagca
     7561 gttgaatata gtggtttagt tagagttggt gaagatgtat attattttgg agaaacatat
     7621 acaattgaga ctggttggat atatgatatg gaaaatgaaa gtgataaata ttatttcgat
     7681 ccagaaacta aaaaagcata taaaggtatt aatgtaattg atgatataaa atactatttt
     7741 gatgagaatg gaataatgag aacaggtctt ataacatttg aagataatca ttactatttt
     7801 aatgaagatg gtattatgca atatggttat ctaaatatag aagataagac gttctacttt
     7861 agtgaagatg gtattatgca gattggagta tttaatacac cagatggatt taaatatttt
     7921 gcacatcaaa atactttaga tgagaatttt gagggagaat caataaacta tactggttgg
     7981 ttagatttag atgaaaagag atattatttt acagatgaat atattgcagc aactggttca
     8041 gttattattg atggtgagga gtattatttt gatcctgata cagctcaatt agtgattagt
     8101 gaatagataa aaatacgtta aatatatcct cttatactta aatatataaa aataaacaaa
     8161 atgatacact acataaagtg ttctatctaa tatgaagatt taccaataaa aaggtgaact
     8221 atgatgaatg cacagtagtt caccttttta tatttctaat ggtaacaaaa tattttttta
     8281 tataaaccta ggaggcgtta tgaatatgac aatatctttt ttatcagagc atatatttat
     8341 aaagttagta attttaacta tatcatttga tacattatta ggatgtttaa gtgcaataaa
     8401 aagtcgtaaa tttaattcta gttttggaat agatggagga atcagaaaag tagcaatgat
     8461 agcatgtata ttttttttat cagtagttga cattcttaca aagtttaact ttttatttat
     8521 gttaccacaa gattgtatca attttttaag actaaaacat cttggaatat ctgaattttt
     8581 ctctatttta tttattttat atgaaagtgt aagcatatta aaaaatatgt gcttatgtgg
     8641 attaccagta cctaagagat taaaggaaaa aatagcagtt ttactagatg caatgacaga
     8701 tgaaatgaat gctaaggatg aaaagtaagt aatggtagat ataataaaaa tattaacaaa
     8761 taaaaagtgt tatccaaata agaatagctg aaagttatca taattcatga aactgataat
     8821 gaaaacgagg gagcagatgc caagagacac acaagtatta aatacatata atttcgaagc
     8881 aagtgttcat tactatatgg atgacaaggt agtatatcaa acattggttc acaaagatgg
     8941 tgcatggtca gttggtaaaa tctattaagc tacattagtt acagatatca caaactataa
     9001 tagttaaaca tagaaatatg tgtaaattgt gatggaaatt attcaaaaac acaaaaatac
     9061 gtgatgaagg acaaaatgat agagaaaata agtatcaaac cttaataaat gatttaattg
     9121 atagtttaaa agttatagga aaaatatata aagaaataaa aacattaaaa aaatataaga
     9181 tatgtttaca aattactatc agacaatctc cttatctaat agaagagtca attaactaat
     9241 tgagtatctt taaattgaaa tgttaggaag tgatttaaat atgaaaactt aaattataaa
     9301 aaatcaatat taatttatct ttaaaaaata gaaaggagtg tataagattt attttcaaag
     9361 tttaaaaaca agaaaatcaa tttaaatttc agaaggaata aatgtggtta tagaagtgga
     9421 tttattatca aaaataatag tactaggagg tttttatgtc tttaatatct aaagaagagt
     9481 taataaaact cgcatatagc attagaccaa gagaaaatga gtataaaact atactaacta
     9541 atttagacga atataataag ttaactacaa acaataatga aaataaatat ttacaattaa
     9601 aaaaactaaa tgaatcaatt gatgttttta tgaataaata taaaaattca agcagaaata
     9661 gagcactctc taatctaaaa aaagatatat taaaagaagt aattcttatt aaaaattcca
     9721 atacaagtcc tgtagaaaaa aatttacatt ttgtatggat aggtggagaa gtcagtgata
     9781 ttgctcttga atacataaaa caatgggctg atattaatgc agaatataat attaaactgt
     9841 ggtatgatag tgaagcattc ttagtcaata cactaaaaaa ggctatagtt gaatcttcta
     9901 ccactgaagc attacagcta ctagaggaag agattcaaaa tcctcaattt gataatatga
     9961 aattttacaa aaaaaggatg gaatttatat atgatagaca aaaaaggttt ataaattatt
    10021 ataaatctca aatcaataaa cctacagtac ctacaataga tgatattata aagtctcatc
    10081 tagtatctga atataataga gatgaaactt tattagaatc atatagaaca aattctttga
    10141 gaaaaataaa tagtaatcat gggatagata tcagggctaa tagtttgttt acagaacaag
    10201 agttattaaa tatttatagt caggagttgt taaatcgtgg gaatttagct gcagcatctg
    10261 acatagtaag attattagcc ctaaaaaatt ttggcggagt atatttagat gttgatatgc
    10321 ttccaggtat tcactctgat ttatttaaaa caatacctag acctagctct attggactag
    10381 accgttggga aatgataaaa ttagaggcta ttatgaagta taaaaaatat ataaataatt
    10441 atacatcaga aaactttgat aaacttgatc aacaattaaa agataatttt aaactcatta
    10501 tagaaagtaa aagtgaaaaa tctgagatat tttctaaatt agaaaattta aatgtatctg
    10561 atcttgaaat taaaatagct ttcgctttag gcagtgttat aaatcaagcc ttgatatcaa
    10621 aacaaggttc atatcttact aacctagtaa tagaacaagt aaaaaataga tatcaatttt
    10681 taaaccaaca ccttaaccca gccatagagt ctgacaataa cttcacagat actactaaga
    10741 tttttcatga ttcactattt aattcagcta ccgcagaaaa ctctatgttt ttaacaaaaa
    10801 tagcaccata cttacaagta ggttttatgc cagaagctcg ctccacaata agtttaagtg
    10861 gtccaggagc ttatgcatca gcttactatg atttcataaa tttacaagaa aatactatag
    10921 aaaaaacttt aaaagcatca gatttaatag aatttaaatt cccagaaaat aatctatctc
    10981 aattgacaga acaagaaata aatagtctat ggagctttga tcaagcaagt gcaaaatatc
    11041 aatttgagaa atatgtaaga gattatactg gtggatctct ttctgaagac aatggggtag
    11101 actttaataa aaatactgcc ctcgacaaaa actatttatt aaataataaa attccatcaa
    11161 acaatgtaga agaagctgga agtaaaaatt atgttcatta tatcatacag ttacaaggag
    11221 atgatataag ttatgaagca acatgcaatt tattttctaa aaatcctaaa aatagtatta
    11281 ttatacaacg aaatatgaat gaaagtgcaa aaagttactt tttaagtgat gatggagaat
    11341 ctattttaga attaaataaa tataggatac ctgaaagatt aaaaaataag gaaaaagtaa
    11401 aagtaacctt tattggacat ggtaaagatg aattcaacac aagcgaattt gctagattaa
    11461 gtgtagattc actttccaat gagataagtt catttttaga taccataaaa ttagatatat
    11521 cacctaaaaa tgtagaagta aacttgcttg gatgtaatat gtttagttat gattttaatg
    11581 ttgaagaaac ttatcctggt aagttactat taagtattat ggacaaaatt acttccactt
    11641 tacctgatgt aaataaagat tctattacta taggagcaaa tcaatatgaa gtaagaatta
    11701 atagtgaggg aagaaaagaa cttctagctc actcaggtaa atggataaat aaagaggaag
    11761 ctattatgag cgatttatct agtaaagaat acattttttt tgattccata gataataagc
    11821 taaaagcaaa gtccaagaat attccaggtt tagcgtcaat atcagaagat ataaaaacat
    11881 tattacttga tgcaagtgtt agtcctgata caaaatttat tttaaataat cttaagctta
    11941 atattgaatc ttctattggt gattacattt attatgaaaa attagaacct gttaaaaata
    12001 taatccacaa ttctatagat gatttaatag atgagttcaa tctacttgaa aatgtatctg
    12061 atgaattata tgaattaaaa aaattaaata atctagatga gaagtattta atatcttttg
    12121 aagatatctc aaaaaataat tcaacttatt ctgtaagatt tattaacaaa agtaatggtg
    12181 aatcagttta tgtagagaca gaaaaagaaa ttttttcaaa atatagcgaa catattacaa
    12241 aagaaataag tactataaag aatagtataa ttacagatgt taatggtaat ttattggata
    12301 atatacagtt agatcatact tctcaagtta atacattaaa cgcagcattc tttattcaat
    12361 cattaataga ttatagtagc aataaagatg tactgaatga tttaagtacc tcagttaagg
    12421 ttcaacttta tgctcaacta tttagtacag gtttaaatac tatatatgac tctatccaat
    12481 tagtaaattt aatatcaaat gcagtaaatg atactataaa tgtactacct acaataacag
    12541 aggggatacc tattgtatct actatattag acggaataaa cttaggtgca gcaattaagg
    12601 aattactaga cgaacatgac ccattactaa aaaaagaact agaagctaag gtgggtgttt
    12661 tagcaataaa tatgtcatta tctatagctg caacggtagc ttcaattgtt ggaataggtg
    12721 ctgaagttac tattttctta ttacctatag ctggtatatc tgcgggaata ccttcattag
    12781 ttaataatga attaatattg catgataagg caacttcagt ggtaaactat tttaatcatt
    12841 tgtctgaatc taaagaatat ggccctctta aaacagaaga tgataaaatt ttagttccta
    12901 ttgatgattt agtaatatca gaaatagatt ttaataataa ttcgataaaa ctaggaacat
    12961 gtaatatatt agcaatggag gggggatcag gacacacagt gactggtaat atagatcact
    13021 ttttctcatc tccatatata agctctcata ttccttcatt atcagtttat tctgcaatag
    13081 gtataaaaac agaaaatcta gatttttcaa aaaaaataat gatgttacca aatgctcctt
    13141 caagagtgtt ttggtgggaa actggagcag ttccaggttt aagatcattg gaaaataatg
    13201 ggactaaatt gcttgattca ataagagatt tatacccagg caaattttac tggagattct
    13261 atgccttttt cgattatgca ataactacat taaaaccagt gtatgaagac actaatacta
    13321 aaattaaact agataaagat actagaaact ttataatgcc aactataact actgacgaaa
    13381 ttagaaacaa attatcttat tcatttgatg gagcaggagg aacttactct ttattattat
    13441 cttcatatcc aatatcaatg aatataaatt tatctaaaga tgatttatgg atatttaata
    13501 ttgataatga agtaagagaa atatctatag aaaatggtac tattaaaaaa ggaaatttaa
    13561 tagaagatgt tttaagtaaa attgatataa ataaaaataa acttattata ggcaatcaaa
    13621 caatagattt ttcaggtgat atagataaca aagatagata tatattcttg acttgtgagt
    13681 tagatgataa aattagttta ataatagaaa taaatcttgt tgcaaaatct tatagtttgt
    13741 tattgtctgg ggataaaaat tatttgatat ccaatttatc taatactatt gagaaaatca
    13801 atactttagg cctagatagt aaaaatatag cttacaatta cactgatgaa tctaataata
    13861 aatattttgg agctatatct aaaacaagtc aaaaaagcat aatacattat aaaaaagaca
    13921 gtaaaaatat attagaattt tataatggca gtacattaga atttaacagt aaagacttta
    13981 ttgctgaaga tataaatgta tttatgaaag atgatattaa tactataaca ggaaaatact
    14041 atgttgataa taatactgat aaaagtatag atttctctat ttctttagtt agtaaaaatc
    14101 aagtaaaagt aaatggatta tatttaaatg aatccgtata ctcatcttac cttgattttg
    14161 tgaaaaattc agatggacac cataatactt ctaattttat gaatttattt ttgaacaata
    14221 taagtttctg gaaattgttt gggtttgaaa atataaattt tgtaatcgat aaatacttta
    14281 cccttgttgg taaaactaat cttggatatg tagaatttat ttgtgacaat aataaaaata
    14341 tagatatata ttttggtgaa tggaaaacat cgtcatctaa aagcactata tttagcggaa
    14401 atggtagaaa tgttgtagta gagcctatat ataatcctga tacgggtgaa gatatatcta
    14461 cttcactaga tttttcctat gaacctctct atggaataga tagatatatc aataaagtat
    14521 tgatagcacc tgatttatat acaagtttaa taaatattaa taccaattat tattcaaatg
    14581 agtactaccc tgagattata gttcttaacc caaatacatt ccacaaaaaa gtaaatataa
    14641 atttagatag ttcttctttt gagtataaat ggtctacaga aggaagtgac tttattttag
    14701 ttagatactt agaagaaagt aataaaaaaa tattacaaaa aataagaatc aaaggtatct
    14761 tatctaatac tcaatcattt aataaaatga gtatagattt taaagatatt aaaaaactat
    14821 cattaggata tataatgagt aattttaaat catttaattc tgaaaatgaa ttagatagag
    14881 atcatttagg atttaaaata atagataata aaacttatta ctatgatgaa gatagtaaat
    14941 tagttaaagg attaatcaat ataaataatt cattattcta ttttgatcct atagaatcta
    15001 acttagtaac tggatggcaa actatcaatg gtaaaaaata ttattttgat ataaatactg
    15061 gagcagcttc aactagttat aaaattatta atggtaaaca cttttatttt aataataatg
    15121 gtgtgatgca gttaggagta tttaaaggac ctgatggatt tgagtatttt gcacctgcca
    15181 atactcagaa taataacata gaaggtcagg ctatagttta tcaaagtaaa ttcttaactt
    15241 tgaatggcaa aaaatattat tttgataatg actcaaaagc agtcactgga tggaggatta
    15301 ttaacaatga gaaatattac tttaatccta ataatgctat tgctgcagtc ggattgcaag
    15361 taattgacaa taataagtat tatttcaatc ctgacactgc tatcatctca aaaggttggc
    15421 agactgttaa tggtagtaga tactactttg atactgatac cgctattgcc tttaatggtt
    15481 ataaaactat tgatggtaaa cacttttatt ttgatagtga ttgtgtagtg aaaataggtg
    15541 tgtttagtgg ctctaatgga tttgaatatt tcgcacctgc taatacttat aataataaca
    15601 tagaaggtca ggctatagtt tatcaaagta aattcttaac tttgaatggt aaaaaatatt
    15661 actttgataa taactcaaaa gcagttaccg gatggcaaac tattgatagt aaaaaatatt
    15721 actttaatac taacactgct gaagcagcta ctggatggca aactattgat ggtaaaaagt
    15781 attactttaa tactaacact gctgaagcag ctactggatg gcaaactatt gatggtaaaa
    15841 aatattactt taatactaac acttctatag cttcaactgg ttatacaatt attaatggta
    15901 aatattttta ttttaatact gatggtatta tgcagatagg agtgtttaaa gtacctaatg
    15961 gatttgaata ctttgcacct gctaatactc ataataataa catagaaggt caagctatac
    16021 tttaccaaaa taaattctta actttgaatg gtaaaaaata ttactttggt agtgactcaa
    16081 aagcaattac tggatggcaa accattgatg gtaaaaaata ttactttaat cctaataatg
    16141 ctattgctgc gactcatcta tgcactataa ataacgacaa gtattacttt agttatgatg
    16201 gaattcttca aaatggatat attactattg aaagaaataa tttctatttt gatgctaata
    16261 atgaatctaa aatggtaaca ggagtattta aaggacctaa tggatttgag tattttgcac
    16321 ctgctaatac tcataataat aacatagaag gtcaggctat agtttaccag aataaattct
    16381 taactttgaa tggcaaaaaa tattattttg ataatgactc aaaagcagtt actggatggc
    16441 aaactattga tagtaaaaaa tattacttta atcttaacac tgctgttgca gttactggat
    16501 ggcaaactat tgatggtgaa aaatattact ttaatcttaa cactgctgaa gcagctactg
    16561 gatggcaaac tattgatggt aaaagatact actttaatac taacacttat atagcttcaa
    16621 ctggttatac gattattaat ggtaaacatt tttattttaa tactgatggt attatgcaga
    16681 taggagtgtt taaaggacct gatggatttg aatactttgc acctgctaat actcataata
    16741 ataacataga aggtcaagct atactttacc aaaataaatt cttaactttg aatggtaaaa
    16801 aatattactt tggtagtgac tcaaaagcag ttaccggatt gcgaactatt gatggtaaaa
    16861 aatattactt taatactaac actgctgttg cagttactgg atggcaaact attaatggta
    16921 aaaaatacta ctttaatact aacacttata tagcttcaac tggttataca attattagtg
    16981 gtaaacattt ttattttaat actgatggta ttatgcagat aggagtgttt aaaggacctg
    17041 atggatttga atactttgca cctgctaata cggatgctaa caacatagaa ggtcaagcta
    17101 tacgttatca aaatagattc ctatatttac atgacaatat atattacttt ggcaatgatt
    17161 caaaagcggc tactggttgg gcaactattg atggtaatag atattacttc gagcctaata
    17221 cagctatggg tgcgaatggt tataaaacta ttgataataa aaatttttac tttagaaatg
    17281 gtttacctca gataggagtg tttaaaggac ctaatggatt tgaatacttt gcacctgcta
    17341 atacggatgc taacaatata gatggtcaag ctatacgtta tcaaaataga ttcctacatt
    17401 tacttggaaa aatatattac tttggtaata actcaaaagc agttactgga tggcaaacta
    17461 ttaatagtaa agtatattac tttatgcctg atactgctat ggctgcagct ggtggacttt
    17521 tcgagattga tggtgttata tatttctttg gtgttgatgg agtaaaagcc cctgggatat
    17581 atggctaaaa tatatgtttg acaaaaaatt attcctgtga tactcagaaa ttatttttat
    17641 ataataaata ttgagattta attaaaagtc atgtgttatt gtaatacatg acttttagtt
    17701 aaaatttttc tatcatttaa taatctatta ttcttgacta ttttataata aaattcatat
    17761 atggaaatat taatactaaa taattaatag ttgatagaaa atagataata tgctaaaagc
    17821 aaaaactaat ttagagcctt gtaactgttt atttgcaatt ataaaaacat ctttaaacat
    17881 attgactata atataaaata ttaactataa tacaaaacaa tattaattaa ttttctctac
    17941 agctatccct ggtatggtta tttttccacc catagttgat tcataagtta tagttccagc
    18001 acttatacct cttatagtta tgtaatcatc ctctaacact cttgaaggag ttattgattt
    18061 tttataacta catagtacga ccttatcata atttccagac acagctaatc ttatttgcac
    18121 ctcatcacca tcttcaataa cttgaataac cttaccttca aattttacct ttttgtactt
    18181 ataatcatca ggtgttctag ctaattggtc ataagtaata ccagtatcat atcctttctt
    18241 ctcttcttct tcttttttac gttgttcttc agccttttta gcttcttcag ctttacgttg
    18301 attttcagct tcaatagctt tcttttcgtc gtctttcatt ttgaaccatg gttcagcatc
    18361 agacaatttg ctatttaaag tttctatttc tgttttttga gaatctataa ctgatgtttg
    18421 attagaaatg acctcctcat ggtcttcaga acaagctggt gaggatatat tgccaaaaaa
    18481 cacaccaaaa taaatgccag tagagcaata tcctttgtgc tcttaaagaa tttaattatt
    18541 ttcttagagc ttccttttct ttcattacta aattcgttac cctcattttt tttagaaaac
    18601 ataatacaat ctccctttta ttagatatat tttattttaa aatttaaaaa cttaaaataa
    18661 ctagttgact aaaaattata tattcatatt ttcctaaaat atatttcccc taagcataat
    18721 tttacaaaat aaatcaagaa gattcaatat attttgaaaa atgaggtaaa aatgtcagat
    18781 tataatataa ttttcttgaa ggtgaatttt atatattaaa tgaaacataa agtattttat
    18841 ttgtataaaa ctatattatg atgtaattaa atgattcagt actttagagg tggtaaaata
    18901 tagatagatg aaagagcata aataaagtga tataataaaa aattaaatat taactataat
    18961 aaaaaaatat ctggtactaa gtataataca aaaataatat atcagaaaga aggtgaagta
    19021 tgggagaact acaaaaaatt ccaggggtag ggaaagcaac agaaaaatct ttaatcatgt
    19081 taggatatac aactattaaa tcacttaaag atgcaaaccc agcacaaatg tatgaaaagg
    19141 aatgtttaat gcgtggacag cacatagaca gatgtcagtt atatgtatac agatgtgcag
    19201 tatattttgc atcaactgaa aatccagaac cagaaaaatt aaagtggtgg tattggaaag
    19261 attaaaaaat caaaaaagtt agatataaaa aagagttgaa tatccgttta aataataaaa
    19321 actaatactc aactcttttt tagtcgtaaa ttttatgtaa atctatttgt atggctaaat
    19381 atacccatca ataaatgtat aaatatacca atcaataaat gactaaacat actacctaac
    19441 aaaggattaa ataaattact taacaaagca ttctaaaaca attaattaga aactgtttct
    19501 tcaagccatt ttctacattg cccaatattt accatagggt caaagccttg gtcttttccc
    19561 ttatttaaaa gcatatcaca agggaaagta tcacattcac cacaatgatt aagttcctta
    19621 ctttcacagc aagttttaac cttacattct ccaccccaaa atggtttttc catagttggg
    19681 caaccagtgc aatttacttg ttcttttttt gtacaactgt cacaacagac accacatctt
    19741 gattcaaaca tgttcaaaca tcctttccat tatttaaaaa tattataaaa tgattttaga
    19801 tgactacaaa agtgcaaata gttgatttta agtcatctaa atgttaaaca taaaattatt
    19861 aatactggta aatttataaa aactattcca aaaatatttt tgaatatttc aaaacacaat
    19921 aaattacttc aaatcccttt gaatattcca taacactata gattacttta aatccccttg
    19981 aatatatttc acagcattat agattgcttt aaatctcttt gaatatttca taacactata
    20041 gattacttta aatctctttg aatattctac aagactatag attagtttaa attcctttga
    20101 atatttcata acatcataaa ttagtttaaa tctctttgaa tattctacaa gactatagat
    20161 tagtttaaat ccctttgaat atttcataac actatagatt actttaaatt tctttgaata
    20221 ttctacaaga ctatagatta gtttaaatcc ctttgaatat ttcataacac catagattac
    20281 tttaaatccc tttgaatatt ctataacact ataaattact tttaactttt atataaccat
    20341 aaagttttta tctggcactt taaatggagt ttttatatca aatttgcctt ccatcgaata
    20401 accaaactta atttaattac acattccaag agtcaaatat tcattcaata tatttgataa
    20461 ttctatgtta tagccataat taaatataga ttattaaagt taaatattta tttaatgtat
    20521 tgaatgattt tttagctata tttaattaag tttcattata taatataaaa attgtttttg
    20581 cattaagttt taatataaca cataataatt ttaaataata acattattat atattttttt
    20641 att
//
LOCUS       DAMJYN010000068        19960 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.070, whole genome shotgun sequence.
ACCESSION   DAMJYN010000068 DAMJYN010000000
VERSION     DAMJYN010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 19960)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19960)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19960
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.070"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            169..1362
                     /locus_tag="PC466_002706"
     CDS             169..1362
                     /locus_tag="PC466_002706"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase"
                     /protein_id="HDF2770073.1"
                     /translation="MDTLKELFKIGSGPSSSHTMGPQRAAERFKNENPDAESFRAILY
                     GSLAATGKGHLTDYIIEKTIAPKKVEIVWEEDIIKDFHPNGMKFEALDKDKNVTAEWT
                     VYSVGGGTIAEEGQRNSKSNSIYHLDTMDEIVKWCKENNKTLVDFVLECEPKDIKDYI
                     KTIKDAMRKSIDDGLSTDEIIPGKLLLKRRASTFYNAYKKDKSFSTLVYAYALAASEQ
                     NASGNIIVTAPTCGSAGVIPGIFFAMQDFYNYDDEKIIEALLVAGIIGNIIKTNASIS
                     GAEVGCQGEVGAACSMAAAAVAYLKGGTIDHIEYAAEIALEHHLGMTCDPVYGYVQIP
                     CIERNAMAAQRAYDAANYALLTDGSHSVSLDQVVETMKETGIDMMDKYKETAKGGLAK
                     HFFSC"
     gene            1568..2686
                     /locus_tag="PC466_002707"
     CDS             1568..2686
                     /locus_tag="PC466_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HDF2770074.1"
                     /translation="MREASYLQEQLYKHRKSLNPIAEIGRKEYKTSKYIRDYLDKLGI
                     EYEVYLETGIVGVIEGKRPKKDIAFRADIDGLHSEEGVKHLCGHDGHATILLGLIEYL
                     NDNKEDLNDNIVFIFQPAEEGPGGAKALIDEGVLRKYNIDEIYGLHIYPELPEGYVGT
                     REGYFMAQIGDIDIEIVSKSGHGAMPQNGIDGIVIASNFVSSLQTIVSRNISPIDNAV
                     LTIGRIEGGARRNIIAENIKMEGTMRCFSPEVYEKMKLRVRELARGFELAYNCKVNIN
                     IIDDYIAVKNDKDLYQEFVEAIGSDTVVELEPLMISEDFSYYQKEVPGLFFMLGSRNE
                     EKGFVNGLHNINFNFDEKICVNALNVYSKLLKYKEAID"
     gene            2817..3062
                     /locus_tag="PC466_002708"
     CDS             2817..3062
                     /locus_tag="PC466_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small, acid-soluble spore protein, alpha/beta
                     type"
                     /protein_id="HDF2770075.1"
                     /translation="MKEKVQREKKITNGKNTKILTNDDIMKYEIASELGLMDKVGERG
                     WAGLTAKEAGRIGGMLTSRKKRLKKIVEEQNKKDESI"
     gene            3049..3795
                     /locus_tag="PC466_002709"
     CDS             3049..3795
                     /locus_tag="PC466_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HDF2770076.1"
                     /translation="MSQYSDFAFVYDELMNEVDYNGWVKYIEDIIDSEGVKVKNILEL
                     ACGTGNLTIPLTKKNYDIAGIDISDEMLSVAREKAEKEGVELVLLQQDISELDFEISD
                     LDCVLCACDGFNYITYDDDLENVFSKTYELLKKDGIFIFDISSFYKLANILGNNMYGE
                     NREDIAYMWQNYFDEEENLIEMELTFFIKDECGKFERFEEIHQQRAYTEDEIVDMLEK
                     SGFKDIKYYGDFTFDKPSEESQRIFFVCKK"
     gene            4080..4955
                     /gene="hslO"
                     /locus_tag="PC466_002710"
     CDS             4080..4955
                     /gene="hslO"
                     /locus_tag="PC466_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HDF2770077.1"
                     /translation="MRDYVLRATSGNGQVRAFVATTRNTVEEARRLHETTKVATAALG
                     RTLTATSIMGLMMKNDSDKLTVIIKGGGPIGTIIATSDSKGMVKGYVGNPQVEVEDYP
                     NGKLNVAAAVGTEGVVKVIKDLGLREPYNGTYPLVSGEIAEDFTYYFAVSEQTPSVVA
                     LGVLTKEDEVEFAGGFIVQLMPDAEEETIAKLEENVAKLPSITNMLKEGKSPDDILNI
                     VLDGLEPKILDTCEVGFMCECSKERVKTALVAIGKKSLAQIIEEDKKAEVGCQFCNKK
                     YMYSEEELLEILKEM"
     gene            5346..6146
                     /locus_tag="PC466_002711"
     CDS             5346..6146
                     /locus_tag="PC466_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HDF2770078.1"
                     /translation="MESKTKYIGISILILLMIFLIAKNFNGKLEIPIPESNSRKFKSA
                     AVFYPQHQDDEVLWGGSAIVDAIKQCGVDNVYVVLVSDGSGVNVFKANTKFRNLTRKQ
                     KEELRNNEFKSALRELGVKPQNVIILADIDKKEGTHYELMEKTILDFEHKFKGNVTHI
                     AHHYKYDDHIMHRKNGEVLKKLKREGKIKDDLYFVKPKYVKYIPRNERAIYKAMDFDD
                     YNKVKSACYEYKVVNSKRKMYGIGYISAHSYFEHLLNDPELTSVLSED"
     gene            6673..8913
                     /locus_tag="PC466_002712"
     CDS             6673..8913
                     /locus_tag="PC466_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HDF2770079.1"
                     /translation="MSNEFIILKGCKENNLNNISLKIPKRKITIFTGVSGSGKSSIVF
                     ETIAKESQRQLNERFSTFVRSFLPKYGEVKADCIENLSTPIIIDQSRLGGNSRSTLGT
                     ITDVNSFLRALYSRFGSEYIGNANMFSFNDIDGMCPHCHGLGKKLVPNMNQILDMNKS
                     LNEGAILLSGFGVGSWHWNIFAESGFFDINKRICDYSEVELEKFLHGKAEKIKIENAG
                     QTNMTYEGLMVKFNRLYLSRDGEISEATKKKLSKLLIEDRCPICDGRRLNEGVYRSLI
                     NGYNIADLTSMQIDELAEVIKSINEPEAQPLIKGIIEKLNSIIDIGLGYLTLDRETSS
                     LSGGESQRIKMVKYLNSNLVDLMYIFDEPSVGLHPKDVYKLNNLLKKLRDKGNTIIVV
                     EHDPDVIKIADHVVDVGPKAGKYGGKVVYEGSYKNLLTSGTLTGNALSKFLPIKESVR
                     EHSGYLEIKNCNKNNLKNVSIKIPKGVLTLVTGVAGAGKSTLIKDEFLKQNPSAVLID
                     QSPVSANSRSSLATYSGIMNNIRSIFSKTNGVNASLFSSNSEGACDNCKGSGIVEMNL
                     AFMESIKSTCNVCEGKKFKKEVLEYRFQRKNIIEVLEMSVLDAIEFFNLKQIKTKLQC
                     IEKMGIGYLTLGQTLDTLSGGECQRLKLASELNKESSVYILDEPTTGLHMADIENFIS
                     IIEEIVDNGNTVIIIEHNIDVIKRADWIIELGPEGGTKGGRVIFEGIPKQLCNNKISL
                     TAKYIV"
     gene            9327..10862
                     /locus_tag="PC466_002713"
     CDS             9327..10862
                     /locus_tag="PC466_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HDF2770080.1"
                     /translation="MINDILTLLSERSDFFIKLSIEHLMISIISIIIAIVLGGIIGII
                     VSEFHNSSKPILGTINFLYTIPSISMLGFLIPFSGIGNTTAVIALTIYALLPMVRNTY
                     TGITNVDKNILEAARGMGSTDFQILYKIKLPLALPVIMSGIRNMVIMTIALAGIASFI
                     GAGGLGVAIYRGITTNNTAMTISGSILIALLALIFDFILGLVEKFFQRKRKKKNRKKV
                     FAILGSLILIATIFTSYLFNPSKTQTIHIATKPMTEQYILGEMLDILIEKNTGLNVEI
                     TQGIGGGTSNIQPAMENGEFDIYPEYTGTGWNMVLKKNELYTESMFSKLQSEYKTKLK
                     MQWTGMYGFSNSYALAVRKEVADKYNLKNISDLKNVSSKLTFGAEYDFYEREDGYTPL
                     CNTYGLNFKDTVDLDIGLKYQAINEGKIDVMPIFTTDGQYSVSDVIVLKDDKNFYPSY
                     QCGNVVRLEVLEENPELSEVFKMVGDILTDKEMAKMNYDVENNNLEPREVACEFLNKK
                     GLL"
     gene            10878..11639
                     /locus_tag="PC466_002714"
     CDS             10878..11639
                     /locus_tag="PC466_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2770081.1"
                     /translation="MTPIIQFKNIKKQYNDKTIIDNLNLDIEKGEFLTVIGSSGSGKT
                     TLLKMINGLILPDGGNILINQTDIKNEDLIKLRRRIGYCVQGSVLFPHMTVEENISYV
                     PNLLSKKNKLEVKSAVNKWMEIVGLPNDMKVRYPSELSGGQQQRVGIARALASSPEIL
                     LMDEPFGAVDEITRKQLQKEIKEIHKKTGVTIIFITHDIYEALILGTKTLVLNHGVVQ
                     QYDTPENILNTPANQFVDQLLNIRKSIIDDDNLKE"
     gene            11977..12845
                     /locus_tag="PC466_002715"
                     /pseudo
     CDS             11977..12845
                     /locus_tag="PC466_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438778.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
     gene            13039..13290
                     /locus_tag="PC466_002716"
     CDS             13039..13290
                     /locus_tag="PC466_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3781 domain-containing protein"
                     /protein_id="HDF2770082.1"
                     /translation="MNVENELLKNLDRLHTTELGVVRIKKNLSLETNDVVNWCKTKIE
                     SPNAIINRKGKNWYISVYDCIITVNAHSYTIITAHKEKK"
     gene            13402..14181
                     /locus_tag="PC466_002717"
     CDS             13402..14181
                     /locus_tag="PC466_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDF2770083.1"
                     /translation="MNNTVKEKLAESLTSDTTDILPYLPYLLQDFWELGSSPEQMLQL
                     FRKHIPFNEDTKVLDLACGKGAVSVKLAKELNIHIKGIDLIPEFIDYARRKAIEYKVD
                     ALCDFEMNDANSSVKIEHDYDCVIFGAVGDILGNYKETISKLLPTIKSKGFILIDDAY
                     VVDKSTNEQLNFERVYPTYNEWCILFKELGLKLIECIPCLELENDVEEEMNWIITRAN
                     ELIKKYPSQKDMFEQYVISQKNEYTDLQQDLVGATWILQKE"
     gene            complement(14316..14966)
                     /locus_tag="PC466_002718"
     CDS             complement(14316..14966)
                     /locus_tag="PC466_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770084.1"
                     /translation="MNIVMINGSPKVNKNNSQYFLSELKQLIQNDNKVFTFKVDSTSK
                     YPDALNAILNCDRLIIAFPLYVDGIPSHLLHFLEKCEKFLKTQNKKPIPVYAIVNCGF
                     NEGEHNHLAIQMIDHWCKKINFTWVQGIGIGAGEMFGSLESVPLGKGPKKDLGIALKE
                     LSKNILSDNIHIDDSNKSTIFISPNFPRFLYKLMGNHQWNTQAKSNGLTKSDILKK"
     gene            complement(14963..15466)
                     /locus_tag="PC466_002719"
     CDS             complement(14963..15466)
                     /locus_tag="PC466_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HDF2770085.1"
                     /translation="MKLLIHDLTDKELEKLLPKLDDNIKILPNTKEIHKCIGRFGCWI
                     KTPSECVVKDYYSNMGKLINESDGIIIISRCCYGGFSPFVKNVLDKSINYILPYFVIK
                     DNMMRHKSRYDKQINLKAIFYGDCITEAEKETATKLVNGNAINFNIKEHSVCFYENIQ
                     DIRGESI"
     gene            complement(15515..16030)
                     /locus_tag="PC466_002720"
     CDS             complement(15515..16030)
                     /locus_tag="PC466_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HDF2770086.1"
                     /translation="MLEYIILGFLMEKELSGYDLKQIMSESTSYFFDASFGSIYPALK
                     RLETKGYIHYHEVIDGSKLKKLYSITNTGKEVFLEWLKKPINFSKTKQDHLVNIFFYK
                     YLPKEIIETNLKMLITEVELLLNKLSKQKIDVEENHCIDQYTYMYATMIYGVDYYNFV
                     INWCKDLLKNL"
     gene            16346..16837
                     /locus_tag="PC466_002721"
     CDS             16346..16837
                     /locus_tag="PC466_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF2770087.1"
                     /translation="MRTIDIKGENMRELLKWVSIINRYNTNYIDRKLADIGINNSQYF
                     YVLHICNNPGITQDTIFEKILVNPSNITRALANLEKEGFITREPGVKDKRTWHLYPTE
                     KSLECYDEILKITNGYVEELLSSFEKEEQELFMSMLKKVAFLAIDMNEEAKLEAKENG
                     RKI"
     gene            16821..18224
                     /locus_tag="PC466_002722"
     CDS             16821..18224
                     /locus_tag="PC466_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF2770088.1"
                     /translation="MEEKYKEPLEYEKVSKLLTKYAIPSIIAMLVSALYNIVDQIFIG
                     QGVGVLGNAATNVTFPLTTICTAIALLLGIGGASKCSLELGAKNSEKATKAAGNSICL
                     MAVFGISLFIVVSIFLTPLLKFFGSTSEILPYAHTYTKITSIGLPFLIMSTGMSKLIL
                     ADGRPKASMFCMLIGAVINTILNPLFIFVFNMGIAGSALATVIGQLISFGISVHYIKN
                     FQHIKLHKKSFKLDSIIYKHIFALGSSSCFNQLAMTVTQIVMNNTLAYYGARSVYGSE
                     IPLACVGIIIKVNMIFISIIIGISQGMQPIIGYNYGAEKYNRVKEAYKFAVGSATIIS
                     VIAFLCFQFFPRQITSIFGNGNETYFIFAEHYFRTFLFLTFINGVQIVSSTFFTSIGK
                     SVLGLFTSLTRQILFLIPLIVILPMFMGIDGVMFAGPIADAAAAMVCIYFAVHEMKSL
                     TIKQNNLMSNHNKIAEV"
     gene            complement(19166..19759)
                     /locus_tag="PC466_002723"
     CDS             complement(19166..19759)
                     /locus_tag="PC466_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDF2770089.1"
                     /translation="MISDSISKRRSIRKYKNQSISHETIEKIIEAGINAPSSKNRQPW
                     RFVVITEKEKESMLKAMSKGIQNEINDNGLLPGSRQHIAGANYTVEIMKQAPVTIFIL
                     NILGKSPLEKLSPEERFYEMANMQSIGAAIQNMSLTAVELGLGSLWICDVYFAYRELC
                     EWLNTDSQLVAAISLGYPDEEPSRRPRLQLSDVTEWR"
BASE COUNT         7639 a         2151 c         3531 g         6639 t
ORIGIN      
        1 ttttattctc aaaatatgca tattaattta ataaaatata ccaaaatgga aataaaaaat
       61 aaattttatg agaatttaat aactaataat taatatattt aggttataat aaatatgtgc
      121 gtaaaatcta acaataagca ataataccgt aaatttagga ggaataatat ggatacttta
      181 aaggaacttt ttaaaatagg aagtggacct tcaagttctc atactatggg accacaaaga
      241 gcagcagaga gatttaagaa tgaaaaccca gatgcagaaa gttttagagc aatattatat
      301 ggtagtttgg cagctacagg gaaaggtcac ttaactgact atataattga aaaaactata
      361 gcacctaaaa aagtcgaaat tgtttgggaa gaagatatta taaaagattt tcacccaaat
      421 gggatgaagt ttgaagcttt agataaagat aaaaatgtaa cagctgaatg gactgtatat
      481 tctgtaggtg gagggactat agcagaagaa ggtcaaagaa acagtaaaag caatagtata
      541 tatcacttag atactatgga tgagatagta aaatggtgca aagaaaataa taagactttg
      601 gtagattttg tgttggaatg tgaaccaaaa gacataaaag attatataaa aactataaaa
      661 gatgctatga gaaaatctat tgatgatgga ctaagtacag atgaaataat accaggcaag
      721 ttattattaa aaagaagagc aagtacattt tataatgcat ataaaaaaga taagagcttc
      781 tcaacacttg tatatgcata tgcactagca gcttcagagc aaaacgcttc tggtaatata
      841 atagttacag caccaacttg tggttctgct ggagtaatac caggaatatt ctttgcaatg
      901 caggatttct ataattatga tgacgaaaaa ataattgaag cactacttgt agctggaata
      961 ataggtaata taataaaaac taatgcttca atatctggag cagaggtagg gtgtcaaggt
     1021 gaagttggag cagcttgttc tatggcagca gcagcagtag catacttaaa aggtggaact
     1081 atagaccata ttgaatatgc ggcagaaata gcacttgaac atcatttagg aatgacttgt
     1141 gaccctgtat atggatatgt tcaaattcca tgtatagaaa gaaatgcaat ggcagctcaa
     1201 agagcttatg atgcagctaa ttatgcatta ttaactgatg gctcacattc tgtctcctta
     1261 gaccaagttg ttgaaacaat gaaagaaact ggtatagata tgatggataa gtacaaagaa
     1321 acagctaagg gtggacttgc taaacatttc ttctcttgct aaaaataaaa ttttccaata
     1381 ataattcctc tgttttgatt tatgaaacag gggaattatt attaatggtg aattatttaa
     1441 taatgcaaaa tatttttata ttcaatttag ctttttattt ttaattagta taacatgcta
     1501 tataatattt taattataaa gaaatataga aatatttttt aataaattag aaattggagg
     1561 agattacatg agagaggcat catatttaca agaacaactt tataaacata ggaagtcatt
     1621 aaatcctatt gcagagattg ggagaaaaga gtataagact tcaaaatata taagagatta
     1681 tcttgataaa ttaggaattg agtatgaagt ttatttagaa acaggtatag taggtgtaat
     1741 agaaggtaaa agacctaaaa aagatattgc ttttagagct gacatagatg gtcttcatag
     1801 tgaagaaggg gtaaaacatt tatgtggtca tgatggacat gctactatat tacttggatt
     1861 aattgagtat ttaaatgata ataaagaaga cttaaatgat aatatagtat ttatattcca
     1921 accagcagaa gaaggtcctg ggggagcaaa agctttaata gatgaaggag tgcttagaaa
     1981 atacaatatt gatgaaatat atgggcttca tatatatcca gagttaccag aaggttatgt
     2041 aggtacaaga gaaggctatt ttatggctca aataggagat atcgacatag aaatagtgtc
     2101 taaaagtgga catggggcta tgccacaaaa tggtattgat ggtatagtga tagcttcaaa
     2161 ctttgtaagc tcacttcaaa ctatagtgtc tagaaatata agcccaatag acaatgcagt
     2221 gttgactatt ggtagaattg aagggggagc tagaagaaat ataatagctg aaaatataaa
     2281 gatggaaggt actatgagat gtttcagccc agaagtgtat gagaaaatga agcttagagt
     2341 tagagaactt gctagagggt ttgaattggc ttataactgt aaggttaata taaatattat
     2401 agatgattat attgctgtta aaaatgacaa ggatttgtat caagagtttg tagaggctat
     2461 tggaagtgat actgttgtag agttagagcc acttatgata tcagaagatt tttcttatta
     2521 tcaaaaagaa gttccaggat tattttttat gttgggttca agaaacgaag aaaaaggatt
     2581 tgtaaatggt cttcataata taaactttaa ttttgatgaa aagatatgtg taaatgcatt
     2641 gaatgtttat tcaaaattat taaaatacaa agaagcaata gattaggaag ataaattata
     2701 aagattaaaa agcataaata cctaaattta aaaaaaatgt attaataaat accccttata
     2761 tatttgtata aatttatttt aattgacaaa aatacaaata agaaggggtg atttttttga
     2821 aagaaaaagt acaaagagaa aagaagataa ctaatggcaa gaatactaaa atattgacaa
     2881 atgatgatat aatgaaatat gagatagcct cagaactagg tcttatggat aaagttggtg
     2941 aacgtggatg ggcaggactt acagctaagg aagcaggaag aattggaggt atgcttacat
     3001 cacgcaaaaa gaggcttaaa aagattgtgg aggagcagaa taaaaaggat gagtcaatat
     3061 agtgattttg cgtttgtata tgatgaactt atgaatgaag ttgattataa tggttgggtt
     3121 aaatatatag aagatataat agatagtgaa ggtgtaaaag taaaaaatat attggaattg
     3181 gcatgtggca cgggtaatct tacaattcca ttgactaaaa aaaattacga tatagctggt
     3241 atagatatat ctgatgagat gcttagtgta gcaagagaaa aggcagaaaa agaaggagta
     3301 gaattagttt tacttcaaca agatatatca gagcttgatt ttgaaatatc tgatttggac
     3361 tgtgtgcttt gtgcttgtga tggatttaat tatataactt atgatgatga tttggaaaat
     3421 gtattttcaa agacatatga attattaaag aaagatggaa tattcatatt tgatataagt
     3481 tctttttata aattagccaa catattggga aataacatgt atggagaaaa tagagaagat
     3541 atagcgtata tgtggcaaaa ttactttgat gaagaagaga atctaattga aatggaactt
     3601 acattcttta ttaaagatga atgtggaaag tttgaaagat ttgaagagat acaccaacaa
     3661 agagcatata ctgaagatga gatagttgat atgcttgaaa aatctggatt taaggatata
     3721 aaatattatg gggattttac atttgacaaa cccagtgaag aaagtcaaag aatcttcttt
     3781 gtatgtaaaa aataagatat ttttgactat ataagataat tattaaaaat aaccatgata
     3841 taaaaatata gaaaatgcag ttttatagat taaaagtaaa gtgatgatac tttatgactt
     3901 ttattttcta ataattataa agttctatag ataaaaatta aaatataata actattgctt
     3961 agtaaaatta aaataaaatg ggttttgccc aaggttaata tagataagta cttatagatt
     4021 aaaattaagg tagtaatata ataaaaataa gacaattaac gggacatgga ggaatattaa
     4081 tgagagatta tgtactaaga gcgacatcag gaaatggtca agttagagca tttgtcgcaa
     4141 ctactagaaa tacagtagaa gaagctagaa gattacatga aactacaaaa gtagcaacag
     4201 cagcacttgg aagaacatta acagccacat ctataatggg attaatgatg aaaaatgata
     4261 gtgataaatt gactgtaata ataaaaggtg gaggtccaat tggaactatt atcgccacat
     4321 cagattctaa gggaatggta aaaggatatg taggaaatcc acaagtagag gttgaagact
     4381 atccaaatgg aaagttaaat gtagcagcag cagtaggtac agaaggtgtt gtaaaagtta
     4441 taaaagactt aggtcttaga gaaccatata atgggactta tccattggta agtggagaaa
     4501 ttgcagaaga ctttacttat tattttgctg tatcagagca gactccatca gtagtagctt
     4561 taggtgttct tacaaaagaa gatgaagtag agtttgctgg aggatttata gttcaattaa
     4621 tgccagatgc agaagaagag actattgcta agttagagga aaatgtagct aaattacctt
     4681 ctataactaa catgttaaaa gaaggaaaat caccagatga tatattaaat attgttttgg
     4741 atggtttgga acctaaaata cttgatacct gtgaagtagg gtttatgtgt gaatgttcaa
     4801 aagaaagagt aaaaactgct ttggttgcaa ttggtaaaaa atcattggct cagataatag
     4861 aagaagataa aaaagcagaa gttggttgcc agttctgtaa taagaagtat atgtatagtg
     4921 aagaagagtt gcttgaaatt ttaaaggaaa tgtaggctat aaaaatagtt gtattgatat
     4981 aagtaatgtt atagtgatat agtaaagtcg tattgatata gtaattaaag tataatttat
     5041 taataataga catatttata ttaaaaaata aatttaataa atttttaagc ttaataaatt
     5101 ttaagaatta agaagctttc tggctgtaat atttgcaatg ttgcagttag aaggcttttt
     5161 tattttatta tagttcgtgt caaagattgt atgaaacaat aaaatattgt aaaataattt
     5221 gtatatttag acctgattga cacaaaggtt tataagatat ttgagttgat tatacgaaat
     5281 tctatgaagt agtaaccctg tgactttaat catgggaggt tcagaagaag gagaaaattt
     5341 taaatatgga aagtaaaacg aagtacatag gaataagtat attaatatta ttgatgatat
     5401 ttttaattgc aaagaatttt aacggaaaac ttgaaatacc tattcctgag agtaatagta
     5461 gaaaatttaa atcagcagca gtgttttatc ctcaacatca agatgatgag gttttatggg
     5521 gaggaagtgc cattgtagat gctataaaac agtgtggtgt tgataatgta tatgtggtat
     5581 tagtatcaga tggttctgga gttaacgttt tcaaagctaa cacaaaattt agaaacttaa
     5641 ctaggaagca aaaggaagag cttagaaata atgagtttaa atcagctttg agagagcttg
     5701 gagtgaaacc tcaaaatgtg attatacttg cagatataga taaaaaggaa ggcacacatt
     5761 atgaattaat ggaaaagact atattggatt ttgaacataa gtttaaaggc aatgtgaccc
     5821 atatagccca tcactataag tatgatgacc atataatgca tagaaagaat ggggaagttt
     5881 taaagaaact taaacgtgaa ggtaagataa aagatgactt gtattttgtt aagccaaaat
     5941 atgtaaagta tataccaaga aatgaaagag ctatctataa agcaatggat tttgatgact
     6001 acaataaggt taagagtgct tgttatgaat ataaggttgt aaattcaaag cgtaaaatgt
     6061 atggtatagg atatatttcg gcacatagtt attttgaaca tcttctaaat gaccctgaac
     6121 ttacgtctgt attaagtgaa gattaatttc ttataagtag taagttatgt ttgataagtt
     6181 gattggaatt ttctatagtt ttgaaggtat tggaaattta gttttattta aagatttaaa
     6241 gatagaggtt tttaatgttt aaaattttaa agttaagttg aataattgta tagaattatt
     6301 tgtgaaagaa gaaacagtgt aaaacatagt atcttattta tggttttaaa atcataggca
     6361 agatactttt tttatgtaac taataccatt ttgaggttat taacttaaga attttatata
     6421 atttaacact catatataat gatgatattt aggtagaata gatgcaatta cgcttaaata
     6481 aaataactgt attttttata aaaatcaaac cctacactat actaccagat aaaatctaca
     6541 tgctataatt tgacctgtgt ttataaaaaa aggagtaatc taataaaata gtatttcact
     6601 tatgtataac taacaactat tattacgatt ttctctaaat aatttaaaga aaaataatgc
     6661 aggaggtaaa atatgagcaa tgaatttata attttaaaag gttgcaaaga gaataatttg
     6721 aacaatattt ccttaaaaat accaaaaaga aaaataacca tattcacagg ggtgtcgggt
     6781 tctggaaagt catctattgt atttgagaca attgcaaaag aatcacaacg ccaactaaat
     6841 gaaaggttta gtacatttgt aagaagtttt ttacctaagt atggagaggt taaagctgat
     6901 tgtatagaaa atctgtcaac accaattatc atagaccaaa gtagacttgg tggaaattca
     6961 aggtcaaccc taggtactat tacagatgta aattcctttt taagagcttt atattcaagg
     7021 tttggtagtg agtatatagg taatgctaat atgttttctt ttaatgatat tgatggtatg
     7081 tgcccacact gtcatgggct tggaaaaaag ctagttccta atatgaacca aattcttgat
     7141 atgaataaat cattaaatga aggtgctata ttgctttcag ggtttggagt gggttcttgg
     7201 cattggaata tattcgctga atcaggattt tttgatatta ataagaggat atgtgattat
     7261 tcagaagtag aattggaaaa gtttttgcat ggtaaagcag aaaagattaa gatagaaaat
     7321 gctggtcaaa ctaacatgac atatgaggga ttaatggtta aatttaatcg tctatactta
     7381 agtagagatg gagaaatatc tgaggctact aagaaaaaat tgagtaaact tcttatagaa
     7441 gatagatgtc ctatatgtga tggaagaaga cttaatgaag gagtatatag gtctttaatt
     7501 aatggttata atatagcaga tttaactagt atgcaaattg atgaattggc tgaagttatt
     7561 aaaagtataa atgagccaga agcacaacct ttaattaaag gaataataga aaagttaaac
     7621 agtatcatag atataggtct tggatattta acactggata gagagacatc ttctctatca
     7681 ggaggggaat ctcagcgtat aaagatggtt aagtatttaa atagtaatct tgttgattta
     7741 atgtatattt ttgatgaacc aagtgtagga cttcatccaa aagatgtgta taaattaaat
     7801 aatcttttaa aaaaattgcg tgataaaggg aatacaatta tagttgttga acatgaccca
     7861 gatgttatta agattgcaga ccatgttgta gatgtaggac caaaggcagg taagtatggt
     7921 ggaaaagttg tgtatgaagg cagttataaa aatctactta caagtggtac tttgacaggg
     7981 aatgctttaa gtaaatttct tcctattaaa gaaagtgtaa gagaacatag tggatattta
     8041 gaaattaaaa attgtaataa aaacaattta aaaaatgtat ctattaagat acctaaaggt
     8101 gtattgactc tagttactgg agtagcagga gcaggtaaaa gtacgttgat taaggatgaa
     8161 tttttaaagc aaaatcctag tgctgtactt atagaccaaa gccctgtttc agcaaattca
     8221 aggtcgagtt tggcaacata tagtggaatt atgaacaaca taagaagcat attttcaaaa
     8281 acaaatggcg taaatgcttc tttattcagt tcaaattcag aaggagcttg tgataactgt
     8341 aagggttctg gaatagtaga aatgaatctt gcttttatgg agagtataaa gagtacctgc
     8401 aatgtttgtg aaggtaaaaa atttaaaaaa gaagttttag aatataggtt tcaaaggaag
     8461 aatataattg aagttcttga aatgtctgtt ttagacgcaa ttgagttttt taatttaaaa
     8521 cagattaaaa cgaaattaca atgtattgaa aaaatgggta ttggatacct tactttagga
     8581 caaactcttg atactttgtc tggaggagag tgtcaaagat taaagcttgc tagtgaatta
     8641 aataaggaaa gttcagtgta tatattagat gaaccaacaa caggtcttca tatggctgat
     8701 attgagaatt ttataagtat aattgaagag attgtagata atggaaatac ggtcataata
     8761 attgaacaca atatagatgt aattaaaaga gctgattgga ttattgagct gggacctgaa
     8821 ggagggacaa aaggcgggag agtaatattt gaaggtatcc caaaacaatt atgtaacaat
     8881 aaaatatcat taacagcaaa atatatagta taataaataa aatataataa aattataatg
     8941 atattttaat aaatataatg ggtatataaa atgataatta aacttaacag taataaataa
     9001 tgtgagaaat attcaaattt aattaaataa agtgtcagaa atttgtttaa attttagtat
     9061 tttaacgatt ctgacctttt ttcttatttt tatggagagt atcgaagatg gagtctctaa
     9121 tagttacttt tttgtgtcta cttgcaagtt tgattaaaaa atggctatac acacttgtga
     9181 cttcagtcat gggaggttca gattataatc ttaatatata atttgtgaaa taatttgatg
     9241 acgatttgct gatgtataaa caataaagat taactacatt aaaatttaaa tcttgttaag
     9301 taaaacttat aaaaggagag agatggatga taaatgatat tctaacctta ttatctgaaa
     9361 gaagtgattt ttttataaag ctatccatag aacatttgat gatttctatt atttctataa
     9421 taattgcgat tgttttgggt ggtataattg gtattattgt aagtgaattt cataattctt
     9481 ctaaacctat attgggaact atcaattttc tatacaccat tccatctatt tctatgctag
     9541 gatttctgat accattttcc ggaattggaa atactactgc tgttattgca cttaccattt
     9601 atgcattatt gccaatggtt agaaatacat atactggaat tactaatgtg gataaaaata
     9661 ttcttgaagc agctagggga atgggcagta cagattttca gatattgtat aaaataaaac
     9721 ttccattagc cctacctgtt attatgtctg gtattagaaa tatggtgatt atgacaattg
     9781 cattagctgg tatcgcttca tttataggtg ctggaggcct aggtgtagcc atatatagag
     9841 gaatcacgac aaataacaca gcaatgacaa ttagtggaag tatacttatt gctctattag
     9901 ctttaatatt tgattttatt ttagggctgg tagaaaaatt ttttcaacga aaaagaaaaa
     9961 agaaaaatag gaaaaaagtt tttgccattc taggaagcct tattcttata gcaactatct
    10021 ttacgtctta tttatttaat ccttcaaaga ctcaaactat tcatattgct actaaaccta
    10081 tgactgaaca atatattctt ggtgagatgt tggatatttt aattgaaaaa aacacaggtc
    10141 taaacgtgga aattacacaa ggcataggag ggggaacatc taatatccag ccagctatgg
    10201 agaatggaga atttgacatt tatccagagt atacaggtac aggctggaat atggtactta
    10261 agaaaaatga attatatact gaaagtatgt ttagtaaact acagtcggaa tacaaaacta
    10321 aacttaaaat gcaatggact ggtatgtatg gtttttctaa tagctatgca ttagcagtta
    10381 gaaaagaagt tgcagataaa tataatttaa aaaatatatc agacttaaaa aatgtatctt
    10441 ctaaattgac atttggagct gaatatgact tttatgagag agaggatgga tatactccat
    10501 tgtgtaatac atatggactg aactttaaag atacagttga tttagatatt ggattaaaat
    10561 accaagctat caatgaaggt aagattgacg taatgcctat atttacaact gatggtcagt
    10621 atagtgtttc agatgttata gttctaaaag atgataaaaa tttctaccca tcttatcaat
    10681 gtggaaatgt tgttcgtttg gaagtattag aggaaaatcc agaactatca gaggtattta
    10741 agatggttgg agatattttg actgataaag aaatggctaa aatgaattat gacgtagaaa
    10801 acaacaattt agaacctaga gaagttgctt gtgagtttct gaataagaaa ggtcttttat
    10861 aaattggagg aaatataatg acacctatta tacaatttaa aaatattaaa aaacaatata
    10921 atgataaaac tataatagat aatcttaatt tagatataga aaaaggagag tttttgactg
    10981 taattggttc gtctggttct ggtaagacaa cactcttaaa aatgattaat ggtctgattt
    11041 tgccagatgg aggaaatatt ttgataaacc aaacagatat caaaaacgag gacttaatta
    11101 aattaagaag aagaatagga tattgtgtac aaggaagtgt tctttttcct catatgactg
    11161 ttgaagaaaa tatttcatat gtaccaaatc tcctaagtaa aaagaataaa ttagaagtaa
    11221 aaagtgctgt aaacaagtgg atggaaatag tgggattgcc aaatgatatg aaagtgcgtt
    11281 acccatcaga attgtcaggt ggtcagcaac aacgtgtagg gattgcaaga gctttagctt
    11341 cttctccaga aattttatta atggatgaac cttttggtgc agttgatgag attacacgaa
    11401 agcaattaca aaaagagata aaagaaattc ataaaaaaac aggagttacg attatcttta
    11461 ttacgcatga tatttatgaa gctttgattt tgggaacaaa gactttggta ttaaatcatg
    11521 gagttgttca acagtatgat actcctgaga atattttaaa tactcctgct aaccaatttg
    11581 tagaccagtt attgaatata agaaaatcta taatagatga tgataattta aaagaataaa
    11641 tttaaattta aaatcaaatt gttgtgataa aaactattga tttagagcta acttcaagtt
    11701 gtatacttga agtggaaaag ttagattaag gtatagaaga gaatttagca gttggctgta
    11761 gacgaggtaa ctgctgaagg tgctttcaat aaatggctag aacctgtatc tattgaagat
    11821 tataataaat tgaaataaga agctcaatat acagagtaga taggcacttc aaatagaagt
    11881 gtcttttgtg tgccataaaa taaatcaaaa tattagcaaa gaatgtgaaa aacaaaataa
    11941 aataatatgc tatctttaaa ataggagggg tgctatatgg ataacaattt gattaccatt
    12001 gaaaaaactt tagattatat agaaaaacat cttttagatg agatgttaga tttaaatgta
    12061 atttctaaag agataggcta ttcaaagtac catttacata gaatgtttac atcagttgtc
    12121 ggatttagta tacataatta tatacaaaga cgtagactaa ctgaagcagc aagaatgctc
    12181 atttttacag aaaaaccaat tattgaaatt gctttaatct cggggtatga cacacaacgt
    12241 tctttttcaa cagggtttaa aaaaatgttt aagcatagcc ctaagttttt tagaaaacat
    12301 caagattttt taccactaca attaaaattt gatattaata atagaaaaag gttacatgga
    12361 ggtatggttt tagatgttaa aaaagttaat tgtacagata taaatattgt tggctattct
    12421 ggtaaagtaa aaaaaggatt tcatgttatt ggaaaatgtt ggagggattt gcataaaaat
    12481 aaagagttga tagaaaacaa ggtagacttg gattttttaa ttggagttaa tgattatagt
    12541 aattttaaag aaattgaaaa taatcctaca tttacatata ttgcaggtgt tcaagtagct
    12601 acttttggta aattcctaat ggaatggaaa aattcgtatt accgaaaagt aattatattg
    12661 tttttacttt tattgggaaa aatgaggata gtatgcaaaa tgttgtagaa tatatctatc
    12721 aagaatggtt ccttaattca agttgccagt ttaatgaaaa taatttatat gattttgtaa
    12781 aatacggaga aaaaactgat aagaatggtt tgagtgaaat tcagttttgg gttccaatca
    12841 tttaaaagaa gggattatgt ataaagtagg tggatttata taggcaaagt tttataaaag
    12901 tatgtattta taaataattt atagtctgta ggaaagaaat agttttacta taagattatg
    12961 ataaaataca caatactatg ataaaatagt actaaataat agatttaatt ttgcaaagga
    13021 taaagtgttt taataaaaat gaatgtagaa aacgaattac ttaaaaacct agatagattg
    13081 catacaacag agttaggcgt tgtaagaatt aagaaaaatc tttctttgga gacaaatgat
    13141 gtagtgaact ggtgtaaaac taaaatagaa tctccaaatg ccattattaa tagaaaggga
    13201 aaaaactggt atataagtgt atatgattgt attataacag taaacgctca cagttataca
    13261 attattacag ctcataaaga aaagaaatga attgaaaaat acaaaggtca aaagcatttt
    13321 ccactgtttg tagtacctat gaagaagtat ataaaataat attacttttg aataataatt
    13381 taaattttgg aggttgaaaa aatgaataat actgtaaaag aaaaattggc agagtcacta
    13441 acttctgata ctactgatat tttaccttat ttgccttatt tattacaaga tttttgggaa
    13501 ttaggaagtt caccagaaca aatgttacaa ttatttagaa agcatatacc ttttaatgag
    13561 gatacaaaag ttttggattt agcttgtgga aaaggtgctg tatctgtgaa gcttgcaaaa
    13621 gagttgaata tacatatcaa aggtattgat ttgatacctg aatttattga ttatgcgaga
    13681 agaaaggcta ttgaatataa ggttgatgct ttgtgtgatt ttgaaatgaa tgatgctaat
    13741 agttctgtaa aaattgagca cgattatgat tgtgtgattt ttggagctgt aggggatatt
    13801 ttaggtaatt ataaagaaac tataagtaag ctattaccta caataaaaag taaggggttc
    13861 attttaattg atgatgcata tgtagtagat aaatctacaa atgaacagct taattttgag
    13921 agggtgtatc ccacttacaa tgagtggtgt atattgttca aagaattagg tctgaaacta
    13981 attgaatgta taccatgttt agaacttgaa aatgatgttg aagaggaaat gaactggatt
    14041 ataactcgtg caaatgagct aattaaaaaa tatccttctc aaaaagatat gtttgaacaa
    14101 tatgttatta gccaaaaaaa tgaatatact gatttacagc aggaccttgt tggagcaact
    14161 tggattttac aaaaagaata agataaatat tagactagat aatcaatgtt gtagtgaatt
    14221 atcccatgtc tagtgaatat aaataacata aaaaaccgtc aagatgaata gtttattcgt
    14281 gcttgacggt ttttagtatt tgttgaagta aaattttatt tctttagtat atcactttta
    14341 gtcaatccat ttgatttagc ttgagtattc cattgatgat tccccataag tttatatagg
    14401 aatctaggga agttaggtga aataaaaata gtacttttgt tggaatcatc tatatgtata
    14461 ttatcactaa gtatattttt tgaaagttct tttaatgcaa ttcctaaatc ttttttaggt
    14521 cctttaccca aaggtacgga ttctagtgaa ccaaacatct ccccagctcc aattccaata
    14581 ccttgaaccc atgtaaagtt gatttttttg caccaatgat ctatcatttg aattgccaaa
    14641 tgattatgtt caccttcatt gaatccacag ttaactattg catacactgg aataggtttt
    14701 ttattttgtg tttttaaaaa tttttcacat ttctctaaaa aatgaagtaa atgagatgga
    14761 ataccatcta cataaagagg aaatgctatt attaatctat cacaattaag tatggcatta
    14821 agagcgtcag gatacttaga tgtgctatct actttaaatg taaaaacttt attatcattt
    14881 tgaataagtt gttttaattc agataaaaaa tactgtgaat tatttttatt tacttttgga
    14941 ctaccattta tcattactat attcatatgg attcacctct tatatcctgt atattttcat
    15001 agaaacaaac agagtgttct tttatattga aatttatagc atttccattt actaatttcg
    15061 tagcagtttc tttttcagct tctgtaatac aatctccata gaatatagct tttaaattta
    15121 tctgtttatc atatctgctt ttatgacgca tcatattatc ttttattaca aagtatggaa
    15181 gaatataatt aatgctttta tcaagtacgt ttttgacaaa agggctaaac cctccgtaac
    15241 agcatctgct tattataata attccatcgg attcatttat aagtttaccc atgttgctgt
    15301 aataatcttt tacaacacat tcagaaggag ttttaatcca gcaaccaaaa cgaccaatac
    15361 atttgtggat ttcttttgtg tttggaagta tttttatatt gtcatcaagc ttgggtaata
    15421 acttttctaa ttctttgtca gttaaatcat gtattaaaag cttcataaag tccatctcct
    15481 tttattatgt atgtttattt ctaaaaatta tatcttatag atttttcagt aaatctttac
    15541 accaattaat aacaaaatta taatagtcaa ctccataaat cattgtggca tacatatatg
    15601 tatattggtc aatacaatga ttttcttcta catcaatttt ttgtttactt aatttattta
    15661 gaagtaattc tacttcagtt attaacattt ttaagtttgt ttcaattatt tctttgggta
    15721 gatacttgta aaagaatata ttaacaaggt ggtcttgctt tgttttagaa aaatttatag
    15781 gtttctttaa ccattcgaga aatacttctt taccagtatt agttatggaa tatagttttt
    15841 ttaatttgct accatctata acttcgtgat agtgtatata tccttttgtt tctaatcttt
    15901 taagtgcagg atagatactt ccaaagctgg cgtcaaaaaa gtacgaggta ctttctgaca
    15961 ttatttgttt taagtcgtat ccacttaatt ctttttccat taaaaatcct aaaataatgt
    16021 attctaacat attacctcct ggtatcaatc agatatatat cgattcgata tatttattat
    16081 tacagataat aaatattacg tcaagatgct ttttaaaata agctaaaaag aattaggaat
    16141 tattgataaa tatgcaaaaa aattaatata aaaggtaatt aaatatcaat gaagatttaa
    16201 aaatagttaa attaaagtaa gagtctaata tataaaattt atagtaactt tatggtttaa
    16261 atataaactt gtgtgctatt gacaaagtat aaaattagca gtaaaataat tgcatgagca
    16321 aatagattat tgcgaacgca aaaaaatgag gacaatagat attaaaggag agaatatgag
    16381 agagctatta aaatgggttt ccattataaa tagatacaat acaaattata ttgacaggaa
    16441 attggcggat attggaatca ataatagcca atatttttat gtattacaca tatgtaataa
    16501 tccaggtatt acacaggaca ctatatttga gaaaattctt gtgaatccta gtaatataac
    16561 gagagctttg gcaaatttag aaaaagaagg ctttataaca agagaaccag gtgtaaagga
    16621 taaaagaaca tggcatttat atcctacaga aaaatcttta gaatgttatg atgaaatact
    16681 aaaaataaca aatgggtatg ttgaggagtt gttgagttca tttgagaaag aagagcaaga
    16741 gttgtttatg tcaatgttaa agaaagttgc atttttagct attgatatga atgaagaagc
    16801 aaaattggag gcgaaggaaa atggaagaaa aatataagga gccattggaa tatgaaaagg
    16861 tttcaaagtt attaactaag tacgcaattc ctagtattat agcaatgtta gtaagtgctt
    16921 tatataacat tgttgaccaa atatttattg ggcaaggtgt tggtgtattg ggtaatgctg
    16981 ctacaaatgt cacttttcca ctaacaacaa tatgtactgc aattgcatta ttattaggaa
    17041 ttggaggagc gtctaagtgt tcattggaat taggtgctaa aaattcagaa aaagctacaa
    17101 aagcagcagg aaattctata tgcttgatgg ctgtttttgg aataagttta tttatagtag
    17161 tatcaatatt tttaacacca ctattaaaat tctttggctc tacatcagaa atactacctt
    17221 atgcacacac atatacaaaa attacatcaa ttggattacc atttcttata atgtccactg
    17281 gaatgagtaa attgatactt gcagatggga gaccaaaagc ttctatgttt tgtatgttaa
    17341 taggagcagt tattaataca attttgaatc cattattcat ttttgttttt aatatgggaa
    17401 ttgctgggtc tgctttagca actgttattg ggcaacttat atcttttgga ataagtgttc
    17461 attatataaa gaattttcaa catattaaat tacataagaa aagttttaaa ttagatagta
    17521 taatttataa acatatattt gcgctaggtt caagctcatg ttttaatcaa ttagcaatga
    17581 ctgtaacaca gatagttatg aataatacat tggcatatta tggggctagg tcagtttatg
    17641 gaagtgagat tccacttgct tgtgtcggta tcattattaa agtaaatatg atttttatat
    17701 ctataattat tggtatatca caaggtatgc aaccaattat agggtataat tatggggctg
    17761 aaaagtataa tcgtgtaaaa gaagcatata agtttgcagt gggaagtgca actattatat
    17821 ctgttattgc attcttatgt ttccaattct tcccaagaca aattacgtct atatttggta
    17881 acggaaatga gacttatttt atatttgcag aacattattt tagaactttc ttgttcttaa
    17941 catttataaa tggtgttcaa atagtatcat caactttctt tacatcaatt gggaaatcag
    18001 tgttgggact ttttacttct ttgactcgtc aaattttatt tttaattcca ttgatagtaa
    18061 ttttaccaat gtttatggga attgatggag taatgtttgc aggaccaata gcagatgcag
    18121 cagcggcaat ggtatgtata tactttgcag ttcatgaaat gaaatccttg actataaagc
    18181 aaaataattt gatgagtaac cataataaga ttgcagaggt ataagacaat atttaagaag
    18241 tatagaaaat taatttaaga aatataataa actaatttag gaagtgtaga aaattaattt
    18301 aaagaagtat aataaactaa tttaggaagt gtagaaaatt aatttaaaga agtataataa
    18361 actaatttag gaagtataga aaattaatct aaagaagtgt aataaactaa tttaggaagt
    18421 atagaaaatt aatttaaaga agtataatga actaatttag gaagtataga aaattaattt
    18481 aaagaagtat agaaaattaa tctaaagaag tgtaataaac taatttagga agtatagaaa
    18541 gctaatctaa agaagtataa taaactaatt taggaagtat agaaaattaa tctaaagaag
    18601 tataataaac taatttaaga aatatagaaa attaatttaa agaaatacaa tacattaatt
    18661 tttaagtaac attaaattaa tgtaagtaaa ataatgttca tatgaagatt taaaggtgca
    18721 ttttctgaag ctaagtatat gttatgtctc tatatccggt gaagtttaat agctcaagaa
    18781 aatgcactat ttatgatgat tattttgttt tatttccaat tttggaaata actattctaa
    18841 ttaaatctaa aattatacca taaataagaa aagaaagtat agatgctatg taccaataaa
    18901 tcgaaattga ccctgtaatt gttctacatg ggatttgcat gcctgaatcc ataaaaacaa
    18961 aaaaactatc aatggtagaa ataatagaca aaataggatt taatcctatt agaataatac
    19021 tttttgagtc ttgaccaatt tggtggatat aaatctcaaa taatgcaatt aaaaaaaaca
    19081 aaatgtaaaa gatttaataa tttttttcat caaaatacct cacctaatat aaattctgtt
    19141 tgcactattt gcttactata actatttatc tccattcagt cacatcactt aattgtaatc
    19201 taggtcttct tgatggttct tcgtcaggat aacctaaaga tattgctgcc actaattgac
    19261 tatctgtatt taaccattca cataattcac gatatgcaaa gtatacatca caaatccaaa
    19321 gactacctag acctaattcc acagctgtaa gcgacatatt ctgaattgca gctccaattg
    19381 attgcatgtt tgccatttca tagaatcgtt cttcagggga tagcttttct aaaggtgatt
    19441 tacctaatat atttaaaata aaaattgtta ctggagcttg tttcatgatt tcaactgtgt
    19501 aatttgcacc agcgatatgt tgacgacttc ctggaagaag cccattatca ttaatttcat
    19561 tttgaatacc tttgctcatg gctttaagca tagattcttt ttccttttca gtgatgacaa
    19621 caaaacgcca tggttgcctg tttttagatg aaggtgcatt tattccagct tcaattattt
    19681 tctctatagt ttcatgtgaa atgctttgat ttttatattt tctgatactt cgtctttttg
    19741 atatagaatc acttatcatt ttaagtaacc tccgtttatt ttttggaaaa atctatttat
    19801 tttctatttt taattatttt agcattaatc agaaaaaaag tcattgattt tagtatacaa
    19861 ttattaacga ttatattaag gattgtatca aaaagtatgt gattatacta agggattata
    19921 ttagacatta tatttaaaat tgtatgaaag gttgtattta
//
LOCUS       DAMJYN010000069        19339 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.071, whole genome shotgun sequence.
ACCESSION   DAMJYN010000069 DAMJYN010000000
VERSION     DAMJYN010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 19339)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19339)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19339
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.071"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(94..936)
                     /locus_tag="PC466_002724"
     CDS             complement(94..936)
                     /locus_tag="PC466_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDF2770090.1"
                     /translation="MIIQQIYNNNVVLVLDENIKKELILTGCGIGFQKKKGQEIDKSK
                     IERTFVIQDESFLDKISKLASQVDEKFFEISTEIIAYAEENLNTKLYEYIYVALTDHI
                     AFAIKRYHENITIKNDLLHEIKRIHKKEYEIGKWAVDYINKEFDVKFPVDEAGFIAMH
                     IVNSNYKGSSKESLLITKIVKDILNIIRYYYRVEFKEDDINYDRLLTHLKFFAKRLVK
                     KEKINDTNNEIIDIIKVKYEKDYDCAYKIKTHVEKNYDYYVSQDELLYLTLHIKRVIS
                     VLNL"
     gene            complement(1183..1677)
                     /locus_tag="PC466_002725"
     CDS             complement(1183..1677)
                     /locus_tag="PC466_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HDF2770091.1"
                     /translation="MSTLVTLLGLLVCTKISTVFSKKWSNIPLAIYQIVLGIILSILP
                     FKLSFSFNPEIFVICIIAPLLFSEGQNVSRKELLELRKPILLLAFGLVLITVFAGGIF
                     IHFLIPRMPLSVSLALAAVISSTDLVAVKSITQGLNFPKNMMSILEGESLLNDDDRII
                     NIME"
     gene            complement(1829..2800)
                     /locus_tag="PC466_002726"
     CDS             complement(1829..2800)
                     /locus_tag="PC466_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide ABC transporter ATP-binding protein"
                     /protein_id="HDF2770092.1"
                     /translation="MKKEESLLKVEGLKKYFEVKSGLFDKEIKCVKAVDGISFDLKKG
                     ETLAIVGESGCGKSTAGRTILRLIEKTEGKVEFNGVDIYKLEKEELRKLRPKMQMIFQ
                     DPYSSLNPRLNVEQIISEAVIEHNLVPKNEIKDNILNVVESCGLSKYHLNRKPDEFSG
                     GQRQRIGIARALALNPEFIVCDEPVSALDVSIQSQIINLLMDLQDKYKLSYLFISHDL
                     SVVNHIAHRVCVMYLGSIIEIATKGELYLHSQHPYTRALMSAVPVQDPTIKKNRIILK
                     GDIPSPTNPPSGCKFHTRCPYCKEICKKEIPVLKEISRNHFVACHLV"
     gene            complement(2801..3778)
                     /locus_tag="PC466_002727"
     CDS             complement(2801..3778)
                     /locus_tag="PC466_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2770093.1"
                     /translation="MSKALIEVKDLKVYFHTDKGIVKSVNEVSFNINEGETIGIVGES
                     GCGKSVTAMSLMKLLPTSKIEGGEIIFRGKDILKMNEDELMVIRGNEISMIFQEPMTS
                     LNPAFTVGSQIIEGIMIHQDLSKEEAKKKVIDMIKLVEIPRAEEIYNSYPHELSGGMR
                     QRIMIAMALSCNPKLLIADEPTTALDVTIQAQILDIMKNIKEKLNTSIMMITHDLGVV
                     AEMCDKVLVMYAGKIIEVAEVVELFKNPKHPYTIGLLKSKPVLGKNKDKRLYSIPGQV
                     PNPIGIPDSCYFSDRCEKVCDKCRTQIPPLIELNSGHSIACWLYKKEEI"
     gene            3997..5556
                     /locus_tag="PC466_002728"
     CDS             3997..5556
                     /locus_tag="PC466_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF2770094.1"
                     /translation="MKFKKLASLILVSSLMLTFTACASNDKDKSSGSKSGGTVVIPMA
                     SDPDIINGAFANVKEDSLASNIVYAPLYTYEKGNLVNYLAEKVDFKDSKELTIKLKSN
                     LKWHDGKPITAEDVLFTFNTVLDEKQNSPSRQYLLVGEKPVKVEKIDDLTVKITLPTA
                     SESFLYGISKISPIPKHVFEGESNIAKSEKNNNPVGSGAFKFKEWKKGESIVFEKNAD
                     YFGGEPKADSIALKIIPNEASQEAALNNGEISLMKTSAEGYEKAKSNSNLQTYTYSEE
                     RLNYIVFNQNISNMANKEVRQALSYALNRNEMIESAYGKEGSVPAKSILVPEADFYTE
                     EGVEGYDQDTNKAKDLLDKSGVKIDKLKIGYNTGRFGHKNYALVAQQELKKIGIEAEI
                     VPYESKAFFNILFSNSTECDMYVNGYAWGLEPNPYRGMFETGQYCNQTKYSNAEIDAL
                     WEKGFTELNKEKRKEIYKQIQQDISKDAPIYTIDYEQNLMAAQKNLKGIKDAKPSPAI
                     LFEDWSKLYVE"
     gene            5662..6621
                     /locus_tag="PC466_002729"
     CDS             5662..6621
                     /locus_tag="PC466_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2770095.1"
                     /translation="MLKLILNRVKVLIPMLILISILSFGLLELAPGDPADAYINPLMS
                     SQDIENIRVNMGLDKPVYIRYLNWLKNTLSGNLGISYINHMPVTEQIMEKMGNTFILM
                     GTSLIFSILVAIPLGIFLAVNKNSITSKVSSVFNYIGVSIPSFWIGMILISIFSVKLN
                     IFPSGGMHTIGNDSIGDLVKHLVLPVITLGLYNTAIFTNYVEASVNEQLKKQYVITAR
                     AKGLSEKVILFKHVLKNSLTSLVTILGMSIQKLVTGAFVTEVVFSWPGMGRLMIDSIF
                     SRDYTVIMAITMLSALFLILGNLVADILYLLIDPKIKSSKGGF"
     gene            6624..7436
                     /locus_tag="PC466_002730"
     CDS             6624..7436
                     /locus_tag="PC466_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2770096.1"
                     /translation="MFTSILKKLKKDKSFAFACITLSIIIILIIASFILNIDSNAIDT
                     TSKLQEPSLKHIFGTDELGRDYFSRALYGGRISLSVGILSMLISVVFGTAVGVISGYI
                     GGKLDQFLMRLVDMLMSIPSFLVLIVLNTYLTPKVSTIILIIGFLSWMEVSRIVRGET
                     LKIKENEYCLAAKATGIKTRNILLRHIVLNLKETIVVAGSLNIANAILTESALSFLGL
                     GIQLPLASWGNMLQDAQRHIFDKLYLAVFPGLLIFLTVISLTIISKKFSSNT"
     gene            complement(7651..8553)
                     /locus_tag="PC466_002731"
     CDS             complement(7651..8553)
                     /locus_tag="PC466_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDF2770097.1"
                     /translation="MDIKQLKYFVEIVKSGFNLSIASKTLHISQPALSQIIKNFEESE
                     DVYLFERYKGRLNGLTPAGERFYVNAEHIINEYKNMMEDLREDSVQFKGKVRIGIPPL
                     ILGIAFSDVVAQLVANNPDIEFDIVEKGAYDLNRMLILQELDYAVLLHPHKIDKSVVT
                     EHVLQEDELTAFLNINHPLAKKDKIDWNDLNEQLLAIFNPTFMIHHKLMQKFTDENVK
                     LKRYIMSGSWDFLLLSTTNSDFITILPSPVHDFFENSKIIEKPFNHPITWKVILCRPK
                     KERYSHVDQHVFKFIIDFFSKKNS"
     gene            8908..10086
                     /locus_tag="PC466_002732"
     CDS             8908..10086
                     /locus_tag="PC466_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000786547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HDF2770098.1"
                     /translation="MKDVVIVSAVRTPIGSFGGVFKNTSAVQLGTIAVKEAISRVGLN
                     LSEIDEVIIGNVLQTGLGQNVARQIAINSGIPNSVPSYTVNKLCGSGLKSVQLAAQSI
                     TSGENDVVIAGGTENMSQAPYIVPTARFGSKMGDITMVDSMLTDGLIDAFNQYHMGIT
                     AENIATKFEFTREMQDKLALESQNKAENAIKNNRFKEEIVPVDVLIRRGKIETIDKDE
                     YPKLGMTFEGLAKLKPAFKKDGTVTAGNASGINDGAAMLILMSQQKADELGIRPLAKI
                     KSYASAGVEPEVMGTGPIPATRKALKKAGLSINDIDLIEANEAFAAQALAVKNELQID
                     SSKLNVNGGAIALGHPIGASGARILVTLIYEMQKRKVETGLATLCIGGGQGISMVVSR
                     "
     gene            10095..10751
                     /locus_tag="PC466_002733"
     CDS             10095..10751
                     /locus_tag="PC466_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase subunit A"
                     /protein_id="HDF2770099.1"
                     /translation="MNKIVSIDEALSHVKDGDTIMVGGFMANGSPENLIDYLCSKNIK
                     DLTLICNDTGFIDKGVGKMVVNKQFKKIIASHVGLNKETGRQMNNNETDVELVPQGTL
                     AEQIRAAGYGLGGILTPTGIGTLVEEGKQKIVVDSKEYLLEKPIYADVALLFASKVDK
                     AGNLVYKGSMNNFNNLMASAAKITIVEADEIVEIGDIDPNEVNTPGIFVNYIVEGGNL
                     "
     gene            10751..11416
                     /locus_tag="PC466_002734"
     CDS             10751..11416
                     /locus_tag="PC466_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacid CoA-transferase subunit B"
                     /protein_id="HDF2770100.1"
                     /translation="MDKLEMQEYIANRVSKELKDGAVVNLGIGLPTKVANYIPDNVNV
                     ILQSENGFLGLGSAEDGNSSDETIVNAGGQPVTILPGGCFFDSATSFGIIRGGHVDIT
                     ILGALQVDKYGNIANYMIPGKMVPGMGGAMDLVTGAKKVIVAMEHTSKGSAKILNNCT
                     LPLTATNAVDLIVTEMGVMEVTSDGILLKEINPAFTLDDVISATEAPLILSDSLNGKI
                     SVV"
     gene            11521..12297
                     /locus_tag="PC466_002735"
     CDS             11521..12297
                     /locus_tag="PC466_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxybutyrate dehydrogenase"
                     /protein_id="HDF2770101.1"
                     /translation="MVKDKVVFVTGAASGIGKQIAESFLKNGAKVMFSDINQEALNNT
                     ITELQKKGYDCMSVKCDVTKEEEINHAIDKTVEKYGRLDILINNAGLQHVSMIEDFPT
                     DKFEFMIKIMLTAPFIATKKAFPIMKKQGFGRIINMASINGVIGFAGKAAYNSAKHGL
                     IGLTKVAALEAADSGITVNALCPGYVDTPLVRGQFNDLSKTRNIPLENVLEEVLYPLV
                     PQKRLLDVQEIADYAMFLASDNAKGITGQACLLDGGYTAQ"
     gene            12359..13693
                     /locus_tag="PC466_002736"
     CDS             12359..13693
                     /locus_tag="PC466_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HDF2770102.1"
                     /translation="MSIIAPIGIIIGIIAIIYFSVKEIHITIAAPIATLIVVLLNKMD
                     VVTSMLGADKNNYMGALGNYIMSYFAIFLLGSILAKFMEESGATVSIADFILNKVGSN
                     HPYRVLVAIFIVSFILTYGGISLFVVMFAVIPLARTLFKKLDISWNLIQIPLWLGIAT
                     ITMTIIPGTPAIQNVIPIQYLNTSLTAATIPSIVGSIGCATFGLVYMKYALNKSIRKG
                     ETYATYTSKLEEESLDRELPGFFASIFPLLALVIIAITGSTFGSEFMKKNVIYIALIV
                     AILLSAFLFHKFLSSKIQTLSIGASGSIGPIFATSSAVAFGAVIMAAPGFDVFSKLIM
                     SIPGSPLISLTVLTSTMSAITGSSSGALGIVMPNFADYYLSTGLNPELIHRVATIASN
                     ILTIVPQSGVFLTFLSLSKLTHKTGFKETFIVVAVGSLIAEIIVITLGLLMY"
     gene            14190..15116
                     /locus_tag="PC466_002737"
     CDS             14190..15116
                     /locus_tag="PC466_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein"
                     /protein_id="HDF2770103.1"
                     /translation="MMRRNIPTKLKTILALGVLTLATASSAVTASASSLENNVNISNK
                     SLVYSNTKYKFSAKPNCSVKPELKPDKDNSCKDKNHNDKNCNNTNKPEDNNNSDSTNK
                     PDNNKPESNKPEDNNNSGSTNKPDNNKPESNKPEDNNNSGSTDKPNNNKPESNKPEDN
                     NNSDSTNKPDDNNNSGSTSENFSAYQKEVVDLVNIERAKAGLNPLTLDSSISNVATKK
                     SQDMIDNNYFSHNSPTYGSPFDMLKKFGISYKTAGENIAMGQKTPKEVVNAWMNSEGH
                     RKNIMNPNFSKIGVGVAQKSGGSIYWTQIFVG"
     gene            complement(15508..19047)
                     /gene="nifJ"
                     /locus_tag="PC466_002738"
     CDS             complement(15508..19047)
                     /gene="nifJ"
                     /locus_tag="PC466_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HDF2770104.1"
                     /translation="MAKFMKTLDGNTAAAHVAYAFTDVAAIYPITPSSTMAEVVDEWA
                     SQGRKNIFGQTVNVVEMQSEAGASGTFHGSLQGGALTSTFTASQGLLLMIPNMYKVAG
                     ELLPGVFHVSARALASQALSIFGDHQDVMAARQTGCVLLASGSVQEVADIAPVAHLAA
                     IEGRLPFIHFFDGFRTSHEIQKVELLENEDYASLLNFEAVQAFRDNALSPNHPVARGT
                     AQNPDIYFQTREASNKYYQNIVGIVEKYMEKMSNLTGRKHSLFDYYGAEDAKYVLIAM
                     GSVTETIEETIDYLNAKGEKYGLVKVHLYRPFSMKHFLDAMPSTVERICVLDRTKEPG
                     STGEPLYLDVRDVFYGKENAPMIIGGRYGLGSKDTTPSDIKTVFDNLVSEQPKNGFTV
                     GIVDDVTNTSLTPSEPIKIASKGTIRCKFWGLGSDGTVGANKQAIKIIGDHTEKYAQA
                     YFDYDSKKSGGITMSHLRFGDTPIRATYLIDEADYIACHKQSYVYQYDLLKGLKKGGT
                     FVLNTIWDQAGLEEHLPAHMKQYIAKNDIKFYTVNAVKLGQEIGLGNRINMIMQSAFF
                     KLAEIIPEEDAVKYLKDSIVKAYGKKGEKIVNMNYAAVDAGINALVKVEVPASWENAV
                     DADKGEVKEPEFIKNILRPMTAQEGNNLPVSTFNGIEDGTFPCGTAAYEKRGIAVDVP
                     EWIIDNCIQCNQCSFICPHACIRPVLVTEEELANAPEGFEAKKALGKGLEGLKYRIQV
                     SPLDCTGCGNCADICPAKEKALVMKPIDTQLDTELDNWAFAVNPDEVAPKVDVMPANT
                     VKGSQFRQPLMEFSGACAGCGETAYIKVVTQLYGDRMMIANATGCSSIWGASAPSIPY
                     TCNHEGKGPSWANSLFEDNAEYGFGMYTAVKQIRNKIVDAMTELVSMDICEDAKAVFT
                     EWLDSRNDGEASKVASAKVVELLEKPACDCTDEKAKELVKAIKDRKDYLVKRSQWILG
                     GDGWAYDIGYGGLDHVLASGEDVNVLVFDTEVYSNTGGQASKATPAAAMAKFAASGKK
                     SRKKDLGMMAMTYGNVYVAQVAMGADKNQFIKAVLEAEKHDGPSLIIAYAPCINHGLK
                     EGMGRTVANEAQAVACGYWHLYRFNPEVKAEGKNPFTLDSKEPTASFKDFILAQVRYS
                     AIAKQFPEEADGLFAKAEADAKERYEGYKKLAE"
BASE COUNT         6731 a         3009 c         2736 g         6863 t
ORIGIN      
        1 ttaaaattat tattttatat taaattttaa ataatatatt aaaattaaac ataatatatt
       61 aaacctatac attctgtatt aaactactct ttattataaa ttcagtacag atataactct
      121 tttgatatgt aatgttaaat aaagtagttc atcttgactt acatagtaat cataattctt
      181 ttctacatga gtttttattt tatatgcaca atcataatcc ttttcatact ttactttaat
      241 tatatctata atttcattat ttgtatcatt gattttttct ttttttacta atcgttttgc
      301 aaagaatttt aaatgagtca aaagcctatc ataatttata tcatcttctt taaattcaac
      361 tctataataa tatcttataa tatttagtat gtcttttaca attttagtaa ttaacagtga
      421 ttcctttgaa cttcccttat agtttgaatt tactatatgc attgctataa aaccagcttc
      481 atctactgga aatttcacat caaattcttt atttatataa tctacagccc atttaccaat
      541 ctcatattct tttttatgta ttctttttat ctcatgtagt aaatcattct ttatagttat
      601 attttcatga tatcttttaa ttgcaaatgc aatatggtca gtaagtgcta cataaatata
      661 ttcataaagc ttagtattca aattctcctc tgcataagca attatttcag tactaatctc
      721 aaaaaatttc tcatcaacct ggcttgctag tttgctaatt ttatctaaaa agctttcatc
      781 ttgtattaca aaagttcttt caattttact tttatctatt tcttgacctt tctttttttg
      841 aaacccaatc ccacatcctg ttagtattaa ttcttttttt atattttcat ctaaaactaa
      901 tacaacatta ttattataaa tttgttgaat aatcataatc aatatctctc ccaaaataca
      961 atttccctta ttcataaaaa aatacctaaa ttaagataca attcacctgt ataccttaac
     1021 ctaggtattg cctgcttacc agtaacaatc cagcttgtta attcttatat attgtattca
     1081 atttatggtt ttattctatt ataaataaat atatatgtca agtaaattat tgaaaactat
     1141 ttcctatttt ttagtattat ttttaacatc aaaaatcaaa ttttattcca ttatatttat
     1201 gattctatca tcatcattta ataaagattc accttcaagt atactcatca tatttttagg
     1261 aaaatttaat ccttgtgtga ttgattttac tgctactaaa tcagttgaag atattactgc
     1321 tgccaaagca agtgaaacag ataatggcat cctaggaata agaaaatgta taaagattcc
     1381 acctgcaaac acggttatca aaactaaacc aaatgcaaga agcaaaattg gttttctaag
     1441 ctctagtaac tcttttcttg atacattttg tccttcactg aataataatg gagctatgat
     1501 acatattaca aatatttctg gattaaatga aaatgataat ttaaacggca aaatagacaa
     1561 tataatccct agtacaattt gatatattgc aagaggaata ttactccact ttttgctaaa
     1621 tacagttgaa atctttgtac aaaccaataa tcccaacaat gttactaaag ttgacataac
     1681 tacctctctt ttcaataata atattataaa ttaaacttat atatcaacta acttaatatt
     1741 aacaacatga aatcccatct taatcaaaaa aattttcagt ttattctatt attcttatta
     1801 tatacatcaa atttaatttt tgaaatatct atactagatg gcatgcaaca aaatgatttc
     1861 ttgatatttc ttttaaaact ggaatctctt ttttgcatat ttccttacaa taagggcatc
     1921 ttgtatgaaa cttacatcca cttggtggat ttgttggaga tggtatgtct ccttttaata
     1981 taattctatt tttcttaatt gtagggtctt gtactggtac tgcgctcata agtgctcttg
     2041 tatatggatg ttgagaatgt aagtaaagtt ctcctttagt tgcaatttct attatagaac
     2101 ctagatacat aacacaaact ctatgtgcaa tatgatttac tacactcaaa tcatgagata
     2161 taaataaata tgagagttta tatttatcct gtaaatccat aagtaaattt ataatttgag
     2221 attgaataga aacatctagt gcagaaacag gttcatcaca aactataaat tctggattta
     2281 atgctaatgc tcttgctata cctatcctct gtctttgacc tccagaaaac tcatctggtt
     2341 ttctatttaa atggtactta gaaagaccac aactttctac aacatttaat atattatctt
     2401 ttatttcatt ctttggcact aaattatgtt ctataactgc ctctgatatt atttgttcca
     2461 catttaatct tggatttaat gaactatatg ggtcttgaaa tatcatttgc attttgggtc
     2521 ttaactttct aagttcttcc ttctctaact tatatatatc tacaccatta aattcaactt
     2581 taccttcagt tttttcaatt aatctaagga tggttcttcc tgcagttgat tttccacatc
     2641 ccgattctcc aactatagcc aaagtttctc ctttttttaa atcaaaagaa attccatcta
     2701 ctgcctttac acatttaatt tccttatcaa ataatccaga tttaacttca aagtactttt
     2761 taagaccttc tacttttaat aaactctctt cttttttcaa ttatatctcc tcctttttat
     2821 ataaccaaca tgcaatacta tgaccactat tcaattctat taaaggaggt atctgagttc
     2881 tacatttatc acatactttt tcacatctat cactaaaata acatgaatct ggtattccaa
     2941 ttggatttgg tacttgtcct ggaatcgaat acaatctttt atctttgttt tttccaagaa
     3001 caggctttga ttttagaagt ccaatagtat aaggatgttt tggattttta aataattcaa
     3061 caacctctgc cacttctata attttaccag catacatcac taatactttg tcacacattt
     3121 ctgcaactac tcccaaatca tgtgtgatca tcattataga tgtgtttaat ttttctttta
     3181 tatttttcat tatatctaaa atctgagctt gaatagtaac atctaaagct gttgttggtt
     3241 catcagctat aagtaatttt ggattacatg ataaagccat agctatcatt attcgttgtc
     3301 tcataccacc tgataattca tgtggatatg aattatatat ttcttcagct cttggtattt
     3361 ctaccagttt tatcatatcg attacctttt tcttagcttc ttcctttgat aaatcttgat
     3421 gtatcataat accttcaatg atttgacttc caacagtgaa cgctgggttt aaagatgtca
     3481 ttggttcttg aaaaatcatt gatatctcat tccctcttat taccataagt tcatcttcat
     3541 tcatctttaa aatgtctttg cctcgaaaga ttatttctcc accttctatt tttgatgttg
     3601 gaagtaactt catcaaagac atggctgtta cagacttacc acatcctgat tctccaacta
     3661 ttccaatagt ttcaccttca tttatattaa aacttacttc atttacactc tttacaatcc
     3721 ctttatctgt atgaaaataa acttttaaat ctttaacctc aattagtgct ttactcatta
     3781 ttttctcctc tcagcaaaat tacttaaaat aacatacacc ttttgattgt attttataaa
     3841 aatttaaatt acaacatttt cttacatttt attatttttt tctattaatt ataataatat
     3901 aatagttaat ttctatatat attgatttaa taatgattac tattatacaa tgaaaaatat
     3961 gtgttaaata ttattttatg gaggttttat aagaatatga aatttaaaaa attggcatca
     4021 ttaatcttag tttcatcatt aatgcttaca tttacagcct gtgcttccaa tgataaagac
     4081 aagtctagtg gaagcaaatc tggtggaact gttgtaatac ctatggcaag tgacccagat
     4141 ataatcaatg gagcttttgc aaacgttaaa gaagactctc ttgcatcaaa tatagtttat
     4201 gctcctcttt atacttatga aaaagggaat ttagtaaatt atttagcaga aaaagtagat
     4261 tttaaagata gtaaggaatt aactataaaa ttaaaatcca atttaaaatg gcatgatgga
     4321 aaaccaataa ctgctgaaga tgtcttattt acatttaata cagttttaga cgaaaaacaa
     4381 aattcaccat caagacaata cttattggtg ggtgaaaaac cagttaaagt agaaaaaatt
     4441 gatgatttaa cagttaagat tactttacca actgcaagtg aatctttctt atatggtata
     4501 tctaaaattt ctccaatacc aaaacatgta tttgaaggag aatcaaatat agctaagtca
     4561 gaaaaaaata ataatccagt tggttctggt gcattcaagt ttaaggaatg gaaaaaaggt
     4621 gaaagcatag tatttgaaaa gaatgcagat tattttggtg gagaacctaa ggcagattct
     4681 atagcgctaa aaataattcc taatgaagca tctcaagaag cagctttaaa taatggcgaa
     4741 atttcactta tgaagacatc tgctgaagga tatgaaaagg caaaatcaaa ctcaaactta
     4801 caaacttata cttatagtga agaaagatta aactacattg tatttaacca aaatatatca
     4861 aacatggcta acaaagaagt aagacaagcc ttatcatatg ccttaaatag aaatgaaatg
     4921 atagaatcag catatggaaa agaaggttct gtacctgcta aatctatatt agttccagaa
     4981 gcagacttct atacagaaga aggtgttgaa ggatatgacc aagatacaaa taaggctaaa
     5041 gacttattgg ataaaagtgg tgttaaaatt gataaattaa aaataggtta taacacaggt
     5101 agatttgggc ataaaaacta tgccttagta gctcaacaag agttgaaaaa aattggtata
     5161 gaagctgaaa tagttcctta tgaaagtaag gcattcttta atatactatt tagtaatagc
     5221 actgaatgtg atatgtatgt aaatggttat gcttggggat tagaaccaaa cccatataga
     5281 ggtatgtttg aaactggtca atattgcaac caaactaaat attctaatgc tgaaatagat
     5341 gctttatggg aaaaaggatt tactgagtta aacaaggaaa aacgtaaaga aatatacaaa
     5401 caaatacaac aggatatatc taaggatgca cctatttaca ctatagatta tgaacaaaat
     5461 ttaatggcag ctcaaaaaaa tctaaaagga ataaaagatg ctaaaccatc tcctgcaata
     5521 ttatttgaag attggtctaa actgtatgta gaataattga tgtaaaattt tatattatta
     5581 attagaaaag gagatgtcta aaaataatat tgttttatta ttttaaaacg agacatctct
     5641 tttaattagg agaatttact tatgttaaaa ttaatattga atagagtaaa agttttaata
     5701 cctatgttaa tcttaatatc tatattatca tttggacttt tagaattagc tcctggtgac
     5761 ccagcagatg catatataaa tcctttaatg tcttcacagg atattgaaaa tataagggtt
     5821 aatatggggc ttgataaacc agtatatata agatatttaa actggttgaa aaacacttta
     5881 agtggaaact taggtatttc ttatataaac catatgcccg ttacagaaca aattatggaa
     5941 aaaatgggaa atacatttat tcttatgggt acttctttga tattttcaat attggtagct
     6001 atacctcttg gaatattttt agctgtaaat aaaaattcaa taactagtaa agtatcatct
     6061 gtttttaatt atataggtgt ttctatccct tctttttgga taggtatgat actcatttca
     6121 attttttcag ttaaacttaa cattttccca tcaggaggta tgcatactat tggaaatgat
     6181 agtattggag atttagtaaa acatttagtt ttgcctgtaa taactttagg tctatataat
     6241 actgctattt ttacaaatta tgtagaagct agtgtaaatg aacaattaaa aaaacaatat
     6301 gttattacag caagagcaaa aggattatca gaaaaagtca tactatttaa acatgtcttg
     6361 aaaaattcac tgacatcatt ggttacaatc ctaggcatga gtatacaaaa attagtcact
     6421 ggtgcatttg ttacagaagt agttttctct tggccaggta tgggaagatt aatgattgat
     6481 tcaatttttt caagagatta tactgtaatt atggcaataa ctatgttatc agcactattt
     6541 ttaattttag gtaatttagt tgctgatata ctatacttat taattgaccc taaaataaaa
     6601 tctagcaaag gaggattcta gttgtgttta caagtatctt aaaaaaatta aaaaaagata
     6661 aatcctttgc ttttgcatgt attactctta gcataataat catattaatt atagcttctt
     6721 ttatattaaa tatagactct aatgcaattg atactacttc taaacttcaa gaacctagct
     6781 taaagcatat ctttggtaca gacgaacttg gtagagatta cttctctaga gctctttatg
     6841 gtggaaggat ttcacttagt gttggtattt tatcaatgct tatctctgta gtatttggta
     6901 ctgctgtagg tgttattagt ggatatattg gaggtaagct agaccaattc ttgatgagat
     6961 tagtagatat gcttatgagt ataccaagtt tcttagtttt gattgtatta aatacttatc
     7021 taacacctaa agtttccact attatactaa ttattggatt cttaagttgg atggaagttt
     7081 caagaattgt acgtggcgaa acattaaaaa taaaggaaaa tgaatactgt ttagctgcta
     7141 aagctactgg tatcaagact agaaatatac tattaagaca tatagtttta aacttaaaag
     7201 agactattgt agtcgctggt tcgttaaata ttgctaatgc tatcttaact gaatccgctc
     7261 ttagtttttt aggtcttgga atccaattac ctcttgcatc atggggtaat atgcttcaag
     7321 atgctcaaag acatattttt gacaagttat atttagctgt atttccagga ttacttatat
     7381 ttttaacagt cataagtttg actataataa gcaaaaaatt ttctagtaat acttaacaaa
     7441 ttttatatag aaaataaaaa cagtgattat ctaaagatat acactgtttt tatttttcgt
     7501 ttaaaaaata catattttgt atattataac tttaaatact actctaccat gttatgtaaa
     7561 gcctattatt gctctcaaac atatagatga aaaactaata gtttattgta ataaaaattg
     7621 atttatttat ttgttatttt aataacattt ttaagagttc tttttactaa agaaatctat
     7681 aataaattta aatacatgtt ggtctacatg gctataacgt tcttttttag gtctacatag
     7741 tataactttc catgtaatag gatgattaaa aggcttttct ataattttgc tattttcaaa
     7801 aaaatcatga actggtgatg gtaaaattgt tataaaatca gaatttgtgg ttgatagcaa
     7861 caaaaaatcc catgaaccag acattatata tctttttaac ttaacatttt catcagtaaa
     7921 tttttgcatt agcttatgat gtatcataaa agtaggatta aatattgcaa gtaattgctc
     7981 attcaaatcg ttccaatcta tcttatcctt cttagcaagt ggatgattta tatttaaaaa
     8041 tgctgtaagt tcatcttctt gaagcacatg ttcagttact acacttttat caattttatg
     8101 tggatgtaac agtactgcat aatctagttc ctgcaagata agcattctat ttaagtcata
     8161 tgcacccttc tctactatat caaattctat atctggatta tttgcaacta actgtgcaac
     8221 tacatctgaa aatgctattc caagtataag tggaggtatt cctattctaa cttttccttt
     8281 aaattgaact gaatcttctc ttaaatcttc catcatattt ttgtattcat ttataatatg
     8341 ttctgcattt acataaaatc tttctcctgc tggtgttaac ccatttaacc tacctttata
     8401 cctttcaaat aaatatacat cttcactttc ttcaaaattt tttataattt gacttaatgc
     8461 tggttgagat atgtgaagtg tcttagatgc tattgataaa ttaaaaccag atttcactat
     8521 ttcaacaaaa tatttcaact gttttatatc cattttaaac ccccttcccc aaaagtataa
     8581 tttagattat attttttctt ctaatgatat tttataggaa aatcaacata atttcattaa
     8641 tattttaaca aaatattttt ctaaatctac tataaatttt tatcctataa atttttctta
     8701 tacactatat aaaaaattag acttagacaa aatgcttttt tcgccgtaat ctataattag
     8761 aaacaggaaa acctaaagca ttaggaataa aagtaattga aatacttaaa aacaagcttg
     8821 tattaaaaaa gtactttatt atagtgttcc ctaatttctt tattcagaaa atttttaatt
     8881 atcattcaag aaaggtaact attagatatg aaagatgtag taatcgtatc agcagtcaga
     8941 acacctatag gaagttttgg aggtgtattt aaaaatactt cagctgttca acttggaact
     9001 atcgctgtta aagaagcgat atcacgtgta ggacttaatt tatctgaaat agatgaagta
     9061 ataattggaa atgttcttca aacagggctt ggacagaatg ttgctaggca aattgctata
     9121 aattcaggta taccaaattc tgttccaagc tacacagtaa ataaattatg tggttcaggg
     9181 cttaaaagtg ttcagctagc tgcccaatca atcacatctg gtgaaaatga tgtggtaatt
     9241 gcaggtggta ctgaaaatat gagccaagct ccttatatcg ttccaactgc tcgctttggt
     9301 agtaaaatgg gtgacataac catggtagat agtatgctaa cagatggcct tattgatgct
     9361 ttcaatcagt atcatatggg aataactgca gaaaatattg caactaaatt tgaatttact
     9421 agagaaatgc aagataaatt ggcattagaa agtcaaaata aggctgagaa tgctataaaa
     9481 aacaaccgct ttaaagaaga aatcgttcca gtagatgttt taatacgtcg aggaaaaata
     9541 gaaactattg ataaagatga atatcctaaa ttaggcatga catttgaagg tttagctaaa
     9601 cttaaacctg cattcaaaaa agatggtact gtaacagctg gaaatgcctc aggtattaat
     9661 gatggtgcgg ctatgttaat actaatgagc caacaaaaag cagacgaact aggtattaga
     9721 ccacttgcta aaataaaatc ctatgcttca gctggtgttg aacctgaagt catgggtact
     9781 ggtccaatcc ctgcaactag aaaagcactg aaaaaagctg gacttagcat caatgatata
     9841 gacttaatag aagcaaacga agcgtttgct gcccaagcat tagctgttaa aaatgaactt
     9901 caaatagatt catcaaagtt aaatgttaat ggtggtgcaa tagcattagg acatccaata
     9961 ggagcaagtg gagctagaat acttgttacc ttaatttatg aaatgcaaaa acgtaaagtt
    10021 gaaactggac ttgcaacact ttgtattggt ggtggtcaag gaatatcaat ggtggtttca
    10081 cgataggagg aaatatgaat aaaatagtta gcattgatga agctctatct catgtaaaag
    10141 atggagatac aataatggtt ggtggattca tggccaatgg ttcaccagaa aatttaattg
    10201 attatttatg tagtaaaaat ataaaagatt tgacactaat ttgcaatgat actggcttta
    10261 ttgacaaagg agttggcaaa atggttgtaa ataagcaatt taaaaagata attgcttctc
    10321 atgtaggatt aaataaagaa actggaagac aaatgaacaa caatgaaaca gatgttgagt
    10381 tagttcctca gggaactctt gctgaacaaa tacgtgcagc tggttatggt ctaggaggta
    10441 tactcacacc gactggtatt ggtactcttg ttgaggaggg aaagcaaaaa attgttgtcg
    10501 atagcaaaga ataccttctt gaaaaaccaa tttatgcaga tgttgctctt ctatttgcat
    10561 caaaggtcga taaagcaggt aatctagttt ataaaggctc tatgaacaat tttaataatt
    10621 taatggcatc tgctgccaaa attacaatag ttgaagcaga tgaaatcgtt gaaattggtg
    10681 acattgaccc aaatgaagtt aatacaccag gtatttttgt gaattacatc gttgaaggag
    10741 gtaatttata atggataaat tagaaatgca agaatatatt gcaaatagag tatctaaaga
    10801 attaaaagac ggagccgttg taaaccttgg aataggtcta ccaaccaaag tagcaaatta
    10861 tattccggat aatgtaaacg ttatcttaca atctgaaaat ggctttttag gtttaggttc
    10921 agccgaagat ggaaattcaa gtgatgaaac tattgtaaat gcaggtggtc aaccagttac
    10981 tatacttcct ggaggatgtt tctttgatag tgctacttct tttggaataa tcagaggagg
    11041 tcatgttgat ataactattc ttggcgcact tcaggttgac aaatatggca atatagcaaa
    11101 ctatatgatt ccaggtaaga tggttccagg tatgggtgga gctatggacc tagtaactgg
    11161 agctaaaaaa gttattgtag caatggaaca tacttcaaaa ggttctgcaa aaatattaaa
    11221 taattgtact cttccactta ctgcaacaaa tgctgtagat ttgatagtta ctgaaatggg
    11281 agttatggaa gtaacatcag atggaatttt acttaaagaa ataaatccag ctttcacatt
    11341 agatgatgtt atttctgcta ctgaagctcc tttaatattg tcagattcat taaatggaaa
    11401 aatatctgtt gtttaaaata attaaaacta gaaaataaaa atctcttaga cgtattacat
    11461 ataaatttgt attgcttaaa atattaatat aaaaataaaa taaaattgga ggaaatgaaa
    11521 atggttaaag ataaagttgt attcgtaaca ggagctgcaa gtggaatagg taaacaaata
    11581 gctgaatcgt tcttaaaaaa tggtgctaaa gtaatgttct ctgatataaa tcaagaagct
    11641 ttaaataata ccataacaga gttacaaaaa aaaggttatg attgcatgag tgtaaagtgt
    11701 gatgtaacta aggaagaaga aattaaccac gctatagata aaactgttga aaagtatggc
    11761 agattagata tattaataaa caatgctgga cttcaacatg tttctatgat agaagatttc
    11821 ccaactgata aatttgaatt tatgataaaa ataatgctga cagcaccttt tatagctact
    11881 aaaaaagcat ttcctataat gaaaaaacaa ggctttggtc gtataataaa tatggcctca
    11941 atcaatggtg taataggatt tgctggaaag gctgcttata actcagcaaa acatggactt
    12001 attggactaa caaaagttgc tgctcttgaa gctgccgatt ctggtataac agttaatgct
    12061 ttatgccctg gatatgtaga tactccactt gtcagaggtc agtttaatga cctttcaaaa
    12121 actcgtaata taccattaga aaatgtctta gaggaagttt tgtacccact tgtaccacaa
    12181 aaacgcctat tagatgttca agaaattgcc gactatgcta tgttcctagc aagtgataat
    12241 gctaagggta ttacaggaca agcttgctta ctagatggag gatatactgc acaatagtta
    12301 ttatatttag ggcttgaaga aagtattctt caggtccttc tactaaggag ggatatttat
    12361 gagtattatc gcaccaattg gtataattat tggtatcata gctattatat atttttcagt
    12421 taaagaaatt catataacta tagctgctcc aatagcaact ttaatagttg ttctcttaaa
    12481 taaaatggat gttgtaacat caatgctagg tgctgacaaa aacaattata tgggtgcact
    12541 tggaaactat ataatgagtt attttgcaat attcttatta ggctcaatac ttgctaaatt
    12601 tatggaagaa agtggagcca ctgtatcaat agctgatttt attttaaata aagttggctc
    12661 taatcatcct tatagagttt tagttgctat atttatagta agttttatat taacgtatgg
    12721 tggtataagc ttatttgtag ttatgtttgc agtcattcca cttgcaagaa ctctatttaa
    12781 aaaacttgat atttcttgga accttattca gataccactt tggcttggta ttgcaacaat
    12841 tactatgact ataattcctg gaacaccagc cattcaaaat gttataccta ttcaatatct
    12901 aaatacgtct cttactgcag ctactatacc aagtattgta ggtagtatag gttgtgctac
    12961 gtttggactt gtctatatga aatatgctct aaacaaaagt attagaaaag gtgaaactta
    13021 cgcaacttac acttcaaaat tagaagaaga atctttagat agagaattac caggattttt
    13081 tgcaagtatt tttcctctat tagcactcgt aattatagct ataactggaa gtacttttgg
    13141 ttcagaattt atgaaaaaaa atgtaattta catagcttta atagttgcaa ttcttttatc
    13201 tgctttttta ttccataaat ttctatcatc taagatacag acattgagca taggtgctag
    13261 tggttctata ggtcctatat ttgctacatc ttctgcagtt gcatttggag cagtaataat
    13321 ggctgcacct ggttttgatg tatttagcaa acttataatg tcaataccag gtagtccact
    13381 tataagtctt actgttttga cttcaacaat gtcagcaata acagggtcct cttctggtgc
    13441 attaggaata gtaatgccaa actttgcaga ttattattta agtactggtc taaatccaga
    13501 attaattcac cgtgttgcta caatagcctc aaatatacta actatagttc cacaaagtgg
    13561 tgtttttctt acattcttaa gcttatctaa gttaacacat aaaactggat ttaaagaaac
    13621 tttcattgta gttgcagttg gttcactaat agcagaaatt attgtaatta cattaggatt
    13681 actaatgtat taatataaaa caaattaaaa ttcataatat gaaaggtggt gtctcaaagt
    13741 gaacttttta cttaatgaga cactcttttt gtatgaaatc aaatatattt taatcatttc
    13801 aacaataaaa aagaaccttt ctctattttg agacaaaccc tttttattcc ttaaagattt
    13861 aaacaattat aatttgttac taatacgaaa acatctattg aataaattta accaaataaa
    13921 aaaaaattta tcataactat aaatttacgt tatggaatta ttataaaaat attattttct
    13981 ctaagtaagt aattccatac tatacaggct tttaatacaa attttcaaac acactgaaat
    14041 atacctattt attccatata tatctttttt acatatcttt acagtaaaaa aagtcttaat
    14101 cttatgttag tatagattca cgggtacccc ctacactaaa ggttacaaat cagtaacatt
    14161 tttagaattt ttagattaag aggtgtttaa tgatgagaag aaatatacca acaaaattaa
    14221 aaactatatt agctttagga gtgttaactt tagcaacagc ttcaagtgct gttactgcaa
    14281 gtgcttcatc acttgaaaat aatgtaaata taagtaacaa aagtttagta tatagtaata
    14341 ctaaatacaa gttttctgca aaaccaaatt gttctgtaaa accagaactt aaacctgata
    14401 aagataactc ttgtaaggat aagaatcata atgacaagaa ttgcaacaac actaataaac
    14461 ctgaggacaa caataattca gactctacta ataagcctga taacaataaa ccagagtcta
    14521 ataaacctga ggacaacaat aattcaggct ctactaataa acctgataac aataaaccag
    14581 agtctaataa acctgaagac aacaataact caggctctac tgataaacct aataacaata
    14641 aaccagagtc taataaacct gaagacaaca ataattcaga ctctactaac aaacctgatg
    14701 ataataacaa ctcaggctct acaagtgaaa atttttcagc ttaccaaaaa gaagttgtcg
    14761 acttagtaaa tatagaaaga gctaaagctg gattaaatcc tcttactctt gattcttcta
    14821 tatcaaatgt tgctacaaaa aaatctcaag atatgattga taacaactat ttttcacaca
    14881 attctccaac ttatggttct ccatttgaca tgttgaaaaa atttggaata agctataaga
    14941 cagcaggtga aaatatagct atgggtcaaa aaactcctaa agaagttgta aacgcatgga
    15001 tgaattctga aggtcacaga aaaaatataa tgaatccaaa tttcagtaaa ataggtgttg
    15061 gagtagcaca aaaaagtggt ggttcaattt attggacaca aatctttgta ggataaaata
    15121 ctctttttcc atgcatatca aaagagtatc tctaagtgat aaaaaacaca aatgagatac
    15181 tcttttgtat ctattttaaa attatcaaat ccaaatatac atactataaa tattatttgt
    15241 tctcttaatt ttagtgtgta gaacaatata taaaaagtat tggcaagatg aaaatggaaa
    15301 acttaaaaag atatttaata ggtaaaaaca ggatcttaat atcttcataa aaaaaggctg
    15361 tctcaaaata gagataaggc ctttttcatt gttgaaatga ttaaaatata tttgatttca
    15421 tacaaaaaga gtgcctcatg aactaaaaag ctcactttga gacactctct tttatcaatt
    15481 ctatataagc attataatac tttaatatta ttcagctaat tttttgtatc cttcatatct
    15541 ttctttagca tcagcttcag ctttagcaaa taatccatca gcttcctctg ggaattgttt
    15601 agctatagca gaatatctta cttgtgcaag tatgaaatct ttgaagcttg cagttggttc
    15661 ttttgaatct aaagtgaatg ggtttttacc ttcagctttt acttctggat tgaatctgta
    15721 taaatgccag tatccgcaag caacagcttg tgcttcatta gccacagttc ttcccatacc
    15781 ttcttttaat ccatggttta tacatggagc ataagctatt attagagatg gcccatcatg
    15841 tttttcagct tctaaaacgg ctttgataaa ttgattttta tcagccccca tagcaacttg
    15901 agctacatat acgtttccat atgtcatagc catcattcct aaatctttct ttctagattt
    15961 tttacctgaa gcagcaaact tagccatagc agcagctgga gtagctttag aagcttgacc
    16021 tcctgtattt gaatatactt ctgtatcaaa tacaagtacg tttacatctt caccagatgc
    16081 aagaacatgg tctaatccac cgtaaccaat atcatatgcc caaccgtctc cacctagtat
    16141 ccattgagat ctcttaacta gataatcttt tctatctttt atagctttta ctaattcttt
    16201 agctttttca tctgtacaat cacaagctgg tttttctaat aattcaacaa ccttagcact
    16261 tgctacttta gaagcttctc catcatttct agaatctaac cactctgtaa atactgcttt
    16321 agcatcttca cagatatcca tagaaactaa ctctgtcata gcatctacta ttttatttct
    16381 tatttgctta acagctgtgt acataccaaa tccatattca gcattatcct cgaataaaga
    16441 atttgcccaa gatggacctt taccttcatg gttacaagta taaggaattg atggtgcaga
    16501 agctccccat atagaagaac atccagtagc attagctatc atcattctat ctccatataa
    16561 ttgtgtaact actttaatgt acgcagtttc tccacatcca gcacatgctc ctgaaaactc
    16621 cattaatggt tgtctaaatt gacttccttt aacagtattt gcaggcataa catcaacttt
    16681 tggagctact tcatcaggat ttactgcaaa tgcccaatta tctaactctg tatcaagttg
    16741 agtatctatt ggcttcataa ctaaagcttt ttctttagct ggacatatgt cagcacagtt
    16801 tccacatcct gtacagtcaa gtggactaac ttgaattcta tattttaatc cttctaatcc
    16861 tttacctaat gcttttttag cttcaaatcc ttctggagca ttagctaatt cttcttcagt
    16921 aactaatact ggtcttatac atgcatgagg acatataaaa gaacattggt tacattgaat
    16981 acagttatct attatccatt caggaacatc aacagctata ccacgttttt cataagctgc
    17041 agtaccacaa gggaatgttc catcttctat accattgaat gtacttactg gtaagttgtt
    17101 tccttcttgt gcagtcattg gtcttagtat attttttata aattctggtt ctttaacttc
    17161 tcctttatct gcatcaacag cattttccca agaagctgga acttcaactt taactaaagc
    17221 atttattcct gcatcaacag cagcatagtt catattaact attttttcac cttttttacc
    17281 ataagcttta actatagaat cttttaagta tttaacagca tcttcttctg gtattatttc
    17341 agctaattta aagaatgcag attgcattat catgtttatt ctgtttccaa gacctatttc
    17401 ttgtcctagt ttaacagcat taactgtata gaattttata tcatttttag ctatatattg
    17461 tttcatatga gctggtaaat gttcttcaag tcctgcttgg tcccatatag tgttaagtac
    17521 aaatgtacca ccttttttaa gaccttttaa taaatcatat tgataaacat atgattgttt
    17581 atgacaggca atataatcag cttcatctat taaataagta gctcttattg gagtatcacc
    17641 aaatcttaag tgagacatag ttataccacc agatttttta gagtcataat caaagtaagc
    17701 ttgagcatat ttttcagtat ggtcaccgat tattttgata gcttgtttat tagctccaac
    17761 agtaccgtca gaacctaatc cccagaactt acatcttata gttcctttag aagctatttt
    17821 tattggctca gatggagtta aagaagtatt agttacatca tcaactatac ctactgtaaa
    17881 tccattttta ggttgttctg aaactaagtt atcaaaaaca gtttttatat ctgaaggagt
    17941 agtatctttt gaacctaatc cgtatcttcc acctattatc ataggagcat tttcttttcc
    18001 atagaataca tcacgtacat ctaagtataa tggttcacca gttgaacctg gctctttagt
    18061 tctatcaagt acacatattc tttcaacagt agatggcata gcatctaaga aatgtttcat
    18121 tgagaatggt ctatataaat gaactttaac taaaccatat ttttctccct tagcatttaa
    18181 gtaatctata gtttcttcta ttgtttctgt tactgaaccc atagctatta atacgtattt
    18241 agcatcttct gctccatagt aatcaaataa actatgtttt ctacctgtta aattactcat
    18301 tttttccatg tatttttcaa ctatacctac tatattttga tagtatttat tagaagcttc
    18361 tctagtttgg aaatatatat ctgggttttg agcagtacca cgagcaactg gatgatttgg
    18421 agataaagca ttatctctaa atgcttgaac tgcttcaaag tttaataaac ttgcataatc
    18481 ttcattttct agtaattcaa ctttttggat ttcatgtgaa gttctgaatc catcaaagaa
    18541 atgtataaat ggtaatctac cttctattgc agctaaatgt gcaacaggtg ctatatcagc
    18601 tacttcttga actgaaccag aagctaataa tacacatcca gtttgtctag cagccataac
    18661 gtcttggtga tccccaaata ttgataacgc ttgagatgcc aaagcacgag cacttacatg
    18721 gaatactcct ggtaataact ctcctgcaac tttatacatg ttaggtatca ttaataataa
    18781 accttgagat gctgtaaaag tagaagttaa agctcctcct tgtaaagaac cgtggaatgt
    18841 tcctgatgca cctgcttctg actgcatttc aacaacatta actgtttgtc caaatatatt
    18901 ttttcttcct tgtgatgccc actcatcaac tacttcagcc atagttgaag atggtgtgat
    18961 tggatatata gctgctacat ctgtaaacgc ataggcaaca tgagctgcag ctgtatttcc
    19021 atcaagtgtt ttcataaact tagccataat atgtatcctc cttgatagct acaattgtac
    19081 ttgtttataa caagtctatt tttttatatt tacatataat ttacacaaca aaaatataaa
    19141 cacacatata gtcgcgcaaa tactctatct tctaatataa tactacagat tagataaaat
    19201 tcctttgaaa attgtaaatt aattacatat ttaagtagat tttttttaaa attaaatatg
    19261 ttaagttttt ttcataattt tgtatacaat atataataaa ttaagttaga cttttcaaac
    19321 ttttttatct atttgttta
//
LOCUS       DAMJYN010000070        18855 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.072, whole genome shotgun sequence.
ACCESSION   DAMJYN010000070 DAMJYN010000000
VERSION     DAMJYN010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18855)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18855)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18855
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.072"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(9..2033)
                     /locus_tag="PC466_002739"
     CDS             complement(9..2033)
                     /locus_tag="PC466_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2770105.1"
                     /translation="MDKKKLILITYDKLNSDHYKEELTNFFGDEIIIETQNILDGIKE
                     NLEGEVVLSLSPLTSNFLIKHFKEDIEIIHGTKALSKLGYEKMMKLPPGTKSLLMTTN
                     KTSAFEMATYLYKIGINHIDFVPTYPDCDEIYDLDTAITPGQIRFIPKYIKNIVDLGW
                     RKISLDTYMSLLVVLKLKNEKFIEKLYKLSKETLSHDFLNTSLDNISKLKTILYMTID
                     EIGDGLIFFNTFNKVTFVNKSLLNMLELDEKLIKSPSLMEYMPKSFLDKITKNLNIDN
                     MIIYIDEIDKKFILSKKPFYLYKNIEGCLITLKDVNNIEILEQKIRSDSVKRGYVAKY
                     KFNNIIGNSSIIKDCIKRAKKMALTDNPILITGETGTGKEAFTQSIHNHSNRKNKPFV
                     AINCASLPSELLESELFGYEDGSFTGAKKGGKKGLFELAHTGTIFLDEIGDMPHDLQV
                     KLLRVLQEKEIRKIGGTSIIPIDVRILAATNKDLEKLIIENKFRMDLFYRISMFTLDL
                     PPLRKRLEDIPLLLESFLKELPYKNIKLDKSLLEALNSYTWMGNIRELRNCVEYMAYM
                     GSNYLTINDLPQNISSKLNNNHMSSNMSIFNDLNQYDKNICISILKSLHMKPMGRTKL
                     MKFMEYNVTEYEVRNMLEYLTRNGYLISSKGRKGSSITEKGIKIIENNII"
     gene            2423..3091
                     /locus_tag="PC466_002740"
     CDS             2423..3091
                     /locus_tag="PC466_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770106.1"
                     /translation="MSKLESTTEKVEVKWYGYVALILGALFFSGIFKDAPGPLKVLDF
                     NNVLGSFGTLGTINDGVGTLASNFRGDGGTGPRDGWLYALTLIPSVMFALGVVRVIDH
                     LDGMKAAQKLLSPLLKPLLGLPGFAGLTLIASLQSTDAAASMTKELKDDGYIDEKQKA
                     VFCAFQFSGASAITNFFASGAALFPFIGDVPIFIPLALILIMKFVGANLLRLYLNKFD
                     KGEA"
     gene            3093..3578
                     /locus_tag="PC466_002741"
     CDS             3093..3578
                     /locus_tag="PC466_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjiG family protein"
                     /protein_id="HDF2770107.1"
                     /translation="MSEVAKKEVKVKKGNVIDAFIGGARNGFQISTNSMAPNVIFGFA
                     IISVFNLTGLLDVIGTIFTPVMSIFGLPGVAATAIMTIFISMGGASGVIAGLFTAGQI
                     SQAHVAILLPMLLLSGAQIQFMGRLLGTAELKTKYYPHMFVIATLNGCIAMLIMNYFV
                     V"
     gene            3639..4760
                     /locus_tag="PC466_002742"
     CDS             3639..4760
                     /locus_tag="PC466_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 peptidase aminoacylase family protein"
                     /protein_id="HDF2770108.1"
                     /translation="MGTNKDYIEYVHKVYDYLHTIPEKGFEEYKTSEFVLKELEKMGF
                     ENINKGVAGTGIIVTIDSKKEGPVFAIRADMDALEFIIDGEKKMIHACGHDGHTSMLL
                     TAAKLIKERNLVKRGKLKILFQPGEEKLYGALRVIDSGLLDDVEEMVGMHLRPGQDCR
                     LGKAIPAMYHCASCIMQFTIKGITCHGSKPHLGVNAVDAVCLAVNAINAIRVNPAIPN
                     SIKVTNISVKGETYNNIPDEAFMALDIRAESNDIIEELKEKAIHAVKTAVSSINAEAV
                     LISKDGVPAAEFDEELVNLAEETIKDVLGADASIGIFKNSGGEDFHYYTQKLKCKTTY
                     IGLGADATPGFHNPNVTFDTKALEYGVDIWCRLVEKRLG"
     gene            5041..6231
                     /locus_tag="PC466_002743"
     CDS             5041..6231
                     /locus_tag="PC466_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HDF2770109.1"
                     /translation="MSKYNFDRVIDRVGTDCVKWDFRTNCSTKAQKDGLPFWIADMDF
                     ECAEPIIEALRKKVEHKIFGYSSNDSDKYFNAVCDWYKRRFNWEINRKDIIFSPGVVP
                     AVAILVRILTNSNEGVIVQKPVYYPFEAKIKSNNRDIVNNPLIYENGTYRMDYDDLEE
                     KAKCSNNKVLILCSPHNPVGRVWREDELKKVVEICKKYDLWIIADEIHSDLVRKGFKH
                     TPLQSLCPEYKDKIITCIAPSKTFNLAGMQLSNIIVNNDELKKKYQEEVTAVGVATSP
                     NPFAIVATIAAYNESEDWLNELNDYLDNNIQFIDEYLKENLPKVKLVYPEGTYLAWLD
                     FTAYGLNEVELEDLMFKKANVLFDEGYIFGKEGIGFERINVACPQSLLKECMDRLKTI
                     FENL"
     misc_binding    6365..6620
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            6679..7680
                     /locus_tag="PC466_002744"
     CDS             6679..7680
                     /locus_tag="PC466_002744"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HDF2770110.1"
                     /translation="MSTIIPKDYKSSLNVIDTQIAIKKLKDFFEMRLSNELNLIRVSS
                     PLFVLPETGANDNLNGEKAVSFDIPFMNKNAEIVQSLAKWKRLALKKYGFEVGSGLYT
                     DMNAIRKNEELDNIHSLYVDQWDWELVIDKSSRNEKTLKDVVKRLYGVFKDTEIFVCS
                     MYEGIKEILPEEITFITSQELEDMYPELSPKEREDKIVKEKKAVFITQIGKTLISGEK
                     HDGRSPDYDDWELNGDILFYNPVLDSALELSSMGIRVDEESLDRQLKLAGCEERKEFD
                     YHKMLLNGELPYTIGGGIGQSRICMYFLQKAHIGEVQVGVWPQDMIQNCSSAGIELL"
     gene            7784..8173
                     /locus_tag="PC466_002745"
     CDS             7784..8173
                     /locus_tag="PC466_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1232 domain-containing protein"
                     /protein_id="HDF2770111.1"
                     /translation="MEFLKIIINIVLDILKKILVRFKNAKFGLVFVFDLLKLPDFMTD
                     KRINIVDKIKVISVLIFTISYFVSGVDIIPEMIAGAFGFIDDAIVLIWSIGIVNEEIN
                     KYRVIIKKDKHSNIIENVEFSIKDEEE"
     gene            8334..9542
                     /locus_tag="PC466_002746"
     CDS             8334..9542
                     /locus_tag="PC466_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dicarboxylate/amino acid:cation symporter"
                     /protein_id="HDF2770112.1"
                     /translation="MKKKIGLVPKLIIGIIVGILIGSYAPEIIVQILVTVSTLFSAFL
                     KFVIPFIIIGFVTAGIADLATGAGKLLGITTGIAYGSTLIAGLLSFAVSTLIFPNFID
                     ASVASQIGDPEAGMLAPIFTIPLEPMVDVTAAIVFAFVMGLGISALRNHGKGETLFNF
                     FQEFQGIVTKTLSTVIIPLLPLYIAGTFANITIAGEVWTILGVFWKVYLVVIPLHFVY
                     MACQFTAAGVFSGKNPVRMLKNQVPGYLTAIGTQSSAATIPVNVGCAEKNGVSKQIRE
                     FVVPLCATIHLSGSMISITGFTTAVLMMNGMPHGIGVLFPYIAMLGIAMVAAPGAPGG
                     AIMSALPFLPMVGIPSDGGLASLMIALYLTQDSFGTACNVSGDNAIAVVVDKINDGMS
                     KKGNKEEQSA"
     gene            complement(9629..10705)
                     /locus_tag="PC466_002747"
     CDS             complement(9629..10705)
                     /locus_tag="PC466_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003415975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HDF2770113.1"
                     /translation="MSTNHGANLYSLSSKYGFSKEEFMDFSSNINPFGTSSLAKQYIV
                     NNIDMVSMYPDPDYIDLKTSISNYCKCSIDNIVLGSGATELISSFIHTINPKQALLLS
                     PAYSEYEKELSKINCSIEKYFAKEEDNFHINLENLIKTINAKDYDLVVICNPSNPTGF
                     AFTKVEVREILKNTDSFLMIDETYVEFTDTDTYSCTQLVDDYSNLFVIRGTSKFFSTP
                     GIRLGYGLISNTNVKNEINKNLDLWNINIIASKMGEIMFSDLDFISNTISLMNTERDY
                     LLKELKNIKSLDIYNTKGNFILCKIKTKELTAKSLREQLLPQKIIIRDCCSFEGLDEY
                     FFRVCILKPNENKLLISSLKAIFK"
     gene            10934..11461
                     /gene="hpt"
                     /locus_tag="PC466_002748"
     CDS             10934..11461
                     /gene="hpt"
                     /locus_tag="PC466_002748"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HDF2770114.1"
                     /translation="MYKVTGKMLTEEQIKEKVYELGKKIEEDFKGEDLLVVGILKGAS
                     VFVSDLIRCIDLDVNIDFMSVTSYGNSTESSGTVKILKDLDVDIEGKNVLIVEDIIDS
                     GLTLSNLVAALKTRNPKSLKLCTLLDKPQRRKANIPVDYVGFVIEDKFIVGYGIDYAE
                     KYRNLPYIGIVEDVE"
     gene            11550..12482
                     /locus_tag="PC466_002749"
     CDS             11550..12482
                     /locus_tag="PC466_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HDF2770115.1"
                     /translation="MDIQLNILLFFQNLRNPILNFIFLVFTISTEAPLLILITTIIYW
                     CINKKCGQKILFAIIGNFVVNLGIKEFVKAPRPIGIKGLESLRVSTAGGYSFPSAHTQ
                     TATTFWVSIMTIFKKRYLHLIGAVMVLGVGLSRLYLAVHWPIDVIVGWMLGIFFTVIF
                     IKIFDYIDDNKNYILLVVLLIPFIIVAIFLNSPEYFEKFGIIVGFVFGYMVEDRFVKF
                     NTDNNNKKINFSNKNKGSKNIIFSRICRFLVGIVTIGMLYIGIKLFISMLIVTLNISD
                     STMSIIFMNFIKNTVVVFYGIAGAPALFKLLKLN"
     gene            12544..13770
                     /locus_tag="PC466_002750"
     CDS             12544..13770
                     /locus_tag="PC466_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDF2770116.1"
                     /translation="MKKVVIIGGGPAGMIAASTACEKGYDVTLIEKNHKLGKKLAITG
                     KGRCNITNACEIEELIENVPTNGKFLYSAFYTFTNDDVISMFNNLGVKTKTERGKRVF
                     PESDKAFDIVNALERQLKSKKVNILLNSKVEKIISKNNKIEKVILNDKKEIKCDSVVV
                     ATGGLSYPLTGSTGDGYKFAISQGHTIIDTKPSLIGIEVQESFTKDLEKLSLRNVEIR
                     VFNSKQKKVYSDFGELEFTRFGLDGPIIKSASCRMKDTRKENYTILLDLKPALDEEKL
                     DKRVQKDFQKYTNKKFEKALDDLLPKKLIPIIINLSEINANTVVHQISREQRKNLVHL
                     LKNLKFTVKRYRPIEEAIITSGGVKVNEINSSTMESKLVEGLFFAGEVIDIDAYTGGF
                     NLQIAFSTGYLAGFNC"
     gene            13854..14075
                     /locus_tag="PC466_002751"
     CDS             13854..14075
                     /locus_tag="PC466_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000002841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta-type small acid-soluble spore
                     protein"
                     /protein_id="HDF2770117.1"
                     /translation="MASNNNNNRTVVPGAKEALNQMKLEIANELGMSNYQQVDKGNLT
                     ARENGYVGGYMTKKLVEMAEQQMAGKSNR"
     gene            14264..14434
                     /locus_tag="PC466_002752"
     CDS             14264..14434
                     /locus_tag="PC466_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770118.1"
                     /translation="MSSVNFEDLKNKFINSDLDEKIRIYTTTEGLSVEQFKELLKYYP
                     IQHLSKLEKALG"
     gene            complement(14527..14988)
                     /locus_tag="PC466_002753"
     CDS             complement(14527..14988)
                     /locus_tag="PC466_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770119.1"
                     /translation="MQIEQLDLETRNKIYCYTKKILRKYQKGITSGKLTADKFADNIL
                     SQHFISSILNEKIVNETNFKISYRNYIETLINIQNENLSNLRKKSTKTAKCFNISQIT
                     QLKNLLSNTGYNLLIPYKYLTARDIEGIVTLINTGSIELGNERIYNYISKA"
     gene            15171..15638
                     /locus_tag="PC466_002754"
     CDS             15171..15638
                     /locus_tag="PC466_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770120.1"
                     /translation="MKMLNGIIKLFYSEIVKTKINNLDSSGYSLRDECKEIRNITLKI
                     DSVFFKLLKLAFGSILLMIAFNLNMILGIGVFLIGVVYILYKRNMEEQVKEHINNVKN
                     NIDISKITFMDEKGRTGLNALITLLLIGLLTGFNWILVASFVVVFVFTIKNVC"
     gene            15681..17444
                     /locus_tag="PC466_002755"
     CDS             15681..17444
                     /locus_tag="PC466_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpoIIE family protein phosphatase"
                     /protein_id="HDF2770121.1"
                     /translation="MTNGSYKMKNLVEISAMVTESTDFFNIKDDIIEKMLEVVHPTKA
                     CVNLFYKNDSKYAYLVCSQTLEYVPQIFPINSLKGAKIDFDTYPEYIHEAVNEKKIIY
                     VENVFEDSRAEGERDLAKAEGYIGRIVFPFIINNVVVGFMTCFLKEDDYITEQDIDFI
                     SSVASLLSLSIEITNKNNNVQILIDKLRGSISAINEATKKLYLNKSIDGFLENLSKQA
                     CNITNSKEALIIINSHHNKDTIVSCYNVEQKKKTNLYPMIDMFLKKESLGGYLNNLKP
                     CSKKGINLESYIYYKLQDKNETIGCIVCANSKNYTSDDLNILSILSKQVSVGMQLYEH
                     NEKEVKHKVLENELNILNKQQQLIMDKGKMDCNDEKELYFYHKPARVVGGDFYYATKV
                     DDEHIVYIVADVMGHGMVSNYVVAMIKGAFKVLCNQYNTPREIMTNLNRMLYDEFDKM
                     GVFTTCLIGIIDTKENMITVSNAGHYSPVVVKKDGTIENNLNCKKGIPIGIMKDATYE
                     NNTLSMEDYAMVCMYTDGILEIKNSSKEEYGINRLENFLKENFRLNQQLIVENLKLDL
                     KNFSSKDNYDDDILIVMLKDR"
     gene            17452..18060
                     /locus_tag="PC466_002756"
     CDS             17452..18060
                     /locus_tag="PC466_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HDF2770122.1"
                     /translation="MDSNDKKGLKSTEIIIINGSPRINKNCSFIANKVKAMLEECGLS
                     CKIFNIYNMDIEYCTACGFCEKTGYCKFNDDMKPLYKMFDDSKGTIVISPVHFDSISA
                     KLKTVVDRTQAIYASKYVLNKPSIDRNKKRIGMYIAVGGSKSYDSQFKGGQIVMDFFF
                     KSINTKLLHNIYLNNTDDVSYIDNQEFKDIIYKNLKIYIDSI"
     gene            18132..18701
                     /locus_tag="PC466_002757"
     CDS             18132..18701
                     /locus_tag="PC466_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate propanoyltransferase"
                     /protein_id="HDF2770123.1"
                     /translation="MKLPIALSNKHVHLSQADIDVLFGAGHELTKFKPLSQPGQYACE
                     EKVDLVGPKGTLKGVRVLGPARAHTQVEISLADGFPLGVKAPIKESGDIAGTPGVKLV
                     GPAGEVEMKEGVIVASRHIHMSNEDAAKFGVTDKQIVKVKTSGPRALVFENVLVRASD
                     SFNLEMHVDMEEGNAAGVKNGDLVELIVD"
BASE COUNT         7216 a         1992 c         3195 g         6452 t
ORIGIN      
        1 ctataggttt aaattatatt attttctatt atttttatgc ctttctcagt tattgatgag
       61 ccttttcttc ctttactaga aattaagtat ccattgcgtg tcaaatattc tagcatattt
      121 cttacttcgt attctgtgac attatattcc ataaatttca ttaactttgt cctccccatt
      181 ggtttcatgt gcaatgattt taggatagaa atgcatatgt ttttgtcata ttggtttaaa
      241 tcattgaata tagacatatt acttgacata tgattattat ttaattttga agatatgttt
      301 tgaggtaaat catttattgt aagataattg gaacccatgt aagccatata ttcaacacaa
      361 tttctcagtt ctctaatatt ccccatccaa gtgtatgaat ttaaagcttc taaaagactc
      421 ttatcgagtt ttatgttttt atagggaagt tcttttaaaa atgattctaa aagaagaggt
      481 atatcttcta atctctttct aagaggaggt aaatctaaag tgaacatact tatcctataa
      541 aataaatcca tcctaaattt attttctata attaattttt ctaaatcttt atttgtggca
      601 gctaatattc tcacatcaat tggaataata cttgtaccac caatttttct aatttctttt
      661 tcttgtaaga ctcttaaaag tttaacctgt aaatcatgtg gcatatctcc tatctcatct
      721 aaaaatatag tgccagtatg agctaattcg aataatcctt tttttccacc tttttttgct
      781 ccagtaaaag aaccatcttc atatccaaat agttcacttt caagtaattc acttggtaat
      841 gaagcacaat ttattgctac aaaaggttta ttttttctat ttgaatgatt gtgtattgac
      901 tgagtaaagg cttctttacc tgttcctgtt tcacctgtta ttaatatagg attatctgta
      961 agagccattt tttttgccct tttaatacaa tcttttataa tagaactatt tccaataata
     1021 ttattaaatt tatatttagc tacataacct cttttgacag aatcacttct tattttttgt
     1081 tctaatattt ctatattgtt tacatctttt aatgtaatta agcaaccctc tatattttta
     1141 taaagataaa atggtttttt agaaagtatg aattttttat ctatttcgtc tatgtatata
     1201 atcatattat cgatatttaa gttctttgta attttatcta agaaactctt tggcatatat
     1261 tccattaagg aaggtgattt tataagtttt tcatctagtt ccaacatatt aagtaaagac
     1321 ttatttacaa aagtaacctt gttaaaggtg ttgaaaaata ttagaccatc acctatttca
     1381 tcaatggtca tgtaaagtat agtttttaat ttagatatat tatctaatga cgtatttaag
     1441 aaatcatgac ttagtgtctc cttggacaat ttgtatagtt tttctataaa tttctcattt
     1501 tttagtttta atactactaa taatgacata tatgtatcta atgagatttt tctccaacct
     1561 aaatcaacaa tattttttat gtattttggt ataaatctaa tctgacctgg tgttatagct
     1621 gtatctaaat catatatttc atcacaatct ggatatgtcg gtacaaaatc tatatgattt
     1681 ataccaattt tatatagata agtagccatc tcaaatgctg aagttttatt ggttgtcata
     1741 agtaacgatt ttgtacctgg aggtagtttc atcatttttt catatccaag ttttgaaagt
     1801 gctttcgttc catgaataat ttcaatatct tccttaaaat gttttattaa aaaattacta
     1861 gttaaaggtg atagagaaag cactacctct ccctctaaat tttcttttat tccatcaagt
     1921 atattttgtg tttctatgat tatttcgtct ccaaaaaagt ttgttaattc ttctttgtag
     1981 tggtcactat ttaatttatc atatgttata aggattaact tctttttatc cattttattt
     2041 ctcctaacaa aatagtattt atttttaaag tatttaaagt ataaggtaag ttatattata
     2101 caacaaatag tagtataaat ttatatattt gattaaataa taggtttttt taggatttta
     2161 tcctataaaa acctatttta aaattatttt tgcaagataa ggaaaatagc tttttatatt
     2221 gtaatgtata ttttaaatag ttaataaaaa aatattatat ttttaaactt gaaaagtaag
     2281 taattataag ctatttaatc gctggaataa atttacaata aaaaaataaa tacaaaggct
     2341 ttatcattaa ggtattggca taagttttgc ttattaaaca agtatactaa taaaattcat
     2401 ttaaacagga gggagaattt atatgagtaa attagaatca acaacagaaa aagttgaggt
     2461 aaaatggtat gggtatgtag cattaatatt gggagcatta tttttttcag gaatatttaa
     2521 agatgcacca ggaccattaa aagtattgga ttttaacaat gtattaggtt cttttggaac
     2581 attgggaaca attaatgatg gtgtaggtac attagcttca aactttagag gtgatggagg
     2641 tactggccct cgagatggat ggctatatgc attgacatta ataccatcag ttatgtttgc
     2701 acttggagta gttagagtta tagaccactt agatggaatg aaggcagctc aaaagcttct
     2761 tagtccacta ttaaagccat tattagggtt acctggattt gcaggactaa ctttgatagc
     2821 tagtttacag tctacagatg cagctgcatc tatgactaaa gaacttaaag atgatgggta
     2881 tatagatgaa aaacaaaaag ctgtattttg tgcatttcaa ttttcaggtg cgtctgcaat
     2941 tacgaatttc tttgcttctg gagcagcact atttccattt ataggagatg taccaatatt
     3001 tataccactt gctttaatat taattatgaa gtttgttggg gcgaacttac ttagattata
     3061 tttaaataaa tttgacaagg gggaagctta acatgagtga ggtagcaaaa aaagaagtaa
     3121 aagttaaaaa aggaaatgtg atagatgcgt ttattggagg agctagaaat ggattccaaa
     3181 taagtacaaa ttcaatggct ccaaatgtca tcttcggttt tgctataatt tctgtgttca
     3241 atttaacagg tcttttggat gtaataggga caatatttac acctgtaatg agtatctttg
     3301 gacttccagg tgttgcagca acagctataa tgacaatatt tatatcaatg ggaggagcat
     3361 ctggagtaat cgcaggttta tttacagcag gtcaaataag tcaagcacat gttgcaattc
     3421 tattgccaat gttattgctt tcaggagcgc agatacaatt tatggggaga cttttgggaa
     3481 cagctgagtt aaaaactaaa tattatccac atatgtttgt tatagcaact ttaaatggtt
     3541 gtattgcaat gcttataatg aattatttcg tagtataggt aattataata aaaatttaat
     3601 ataaatggaa agtttaaatt ttaaggagga gctagattat gggaactaac aaagattata
     3661 ttgagtatgt acataaagtg tatgattatc tacacactat accagaaaaa ggatttgaag
     3721 aatataagac atcagagttt gttttaaaag agcttgaaaa aatggggttt gaaaatatta
     3781 ataaaggagt tgcaggaact ggtattatag taactataga ttctaaaaaa gaaggaccag
     3841 tatttgctat aagagcagat atggatgcat tggaatttat catagatgga gaaaagaaaa
     3901 tgatacatgc ttgtggtcat gatggtcata cttctatgct tttaacagct gcaaagttaa
     3961 taaaagagag aaatttagta aaaagaggta agttaaaaat actttttcaa ccaggtgaag
     4021 aaaaattata tggagcatta agagtaattg attctggttt gttggatgat gtagaagaaa
     4081 tggtagggat gcatttaaga cctggacaag attgtaggtt gggaaaggcg atacctgcaa
     4141 tgtaccattg tgctagctgt ataatgcaat ttacgattaa aggtatcact tgtcatggtt
     4201 ctaaaccaca tttaggagta aatgcagtag atgctgtctg tttagcagtg aatgcaataa
     4261 atgcaataag agtaaatcca gctataccaa attctataaa agtaacaaat atatcagtta
     4321 agggagaaac ttataataat ataccagatg aagcatttat ggctttagat ataagggcag
     4381 aaagtaatga tataatagaa gaattaaaag aaaaagcaat acatgctgta aaaactgctg
     4441 taagttctat aaatgcagaa gctgtactaa tttccaaaga tggagtacca gcagcagaat
     4501 ttgatgaaga acttgtaaac ttggctgaag aaactataaa agatgtattg ggagctgatg
     4561 catctatagg tatatttaaa aattctggtg gagaagattt ccattattat acacaaaaac
     4621 taaaatgtaa aactacatat attggattag gagctgatgc tacaccagga tttcataatc
     4681 caaatgtaac atttgatacg aaagctttag aatatggtgt agatatatgg tgtagattgg
     4741 ttgaaaagag attgggataa tatccaaact aataattcta catttaaaat tataattata
     4801 gaagttatag aaaaagattg cttatgttaa ttagaaaata attaatatga gcaatcttat
     4861 tttgatataa tgaaactgat tttggaatat tgaaaaaata tgatggaaaa gtaattatat
     4921 tttaaatcta ttggacaaaa aagtgatatt attataatat taagaattgt aaaataatac
     4981 caaagtgcat ctagtaatgg acttaacaat tataaaaatt ttattcttag gagggaaaaa
     5041 atgagtaagt ataattttga cagagtaata gatagagtag gaacagattg tgtaaaatgg
     5101 gattttagaa ctaattgttc aacaaaagca caaaaagatg gtttgccttt ttggattgct
     5161 gatatggatt ttgaatgtgc agaaccaata atagaagcat tacgtaaaaa agttgaacat
     5221 aaaatatttg gatatagttc aaatgatagt gataaatact ttaatgcagt ttgtgattgg
     5281 tataaaagga gatttaactg ggaaataaat agaaaagata ttatttttag tcctggtgtt
     5341 gtacctgctg ttgctatttt agtaagaata ttaactaatt ctaatgaagg tgtaatagtc
     5401 caaaaaccag tgtattaccc atttgaagct aagataaaga gcaataatag ggacattgta
     5461 aacaatcctc taatatatga gaatggtact tataggatgg attatgatga tttagaagaa
     5521 aaagctaagt gtagcaacaa taaagtactg atactttgta gtcctcacaa ccctgttgga
     5581 agagtttgga gagaagatga attaaagaag gttgtagaaa tatgtaaaaa atatgaccta
     5641 tggataatag ctgatgagat acattctgat ttagttagaa aaggatttaa acatactcct
     5701 ttacagtcat tatgcccaga gtacaaggat aaaataatta catgtatagc tccaagtaaa
     5761 acatttaatc tggcaggaat gcagttgtct aatataatag tgaataatga tgaactaaaa
     5821 aagaaatatc aagaagaggt tacagctgtt ggagttgcaa cttcaccaaa tccctttgct
     5881 attgtagcta caatagcagc atataatgaa agtgaagact ggcttaatga attaaatgat
     5941 tacttagata ataatataca atttattgat gaatacttaa aagaaaacct accaaaagta
     6001 aaacttgttt atccagaagg aacatatcta gcatggttag attttactgc ttatggatta
     6061 aatgaagtag aacttgagga tttaatgttt aaaaaagcta atgtattatt tgatgaaggt
     6121 tatatatttg gaaaagaagg aataggattt gaaagaataa atgtagcttg tccacagtct
     6181 ttattaaaag aatgtatgga cagattaaag actatatttg aaaatttata aagtataggt
     6241 aaaaatttat aaagtgttta aaaataaaaa aataataaac ttgacaaatt ttaactaatc
     6301 acttatcata ctattatgaa taaatagaaa acataagaga gctaaatttt attgaattaa
     6361 actcttaaag actttgaaag gaagagtagt tatagaatgt aattaaagcg agttggtgat
     6421 ggtgtgagac caatatgaag tctataatga agaacatcct ggagttgcta accgaaattt
     6481 taaaagagta ggcttagtcg gaaccaaacc gttatcatat tggggtgtat cgagtaatat
     6541 ctgtacattg tgagctgggt ttgaatttat ttcaaactaa tcagggtggt accgcggaaa
     6601 agcaaccttt cgtccctttt atatagggat gaagggtttt tttaatggaa aaatatataa
     6661 atatagggag tgaatgatat gagcacaata ataccaaagg attataaaag tagtttgaac
     6721 gtaattgata cacaaatagc tataaaaaaa ttaaaagatt tttttgaaat gagactaagt
     6781 aatgaattaa atcttataag agtttcttct ccgttatttg tattgccaga aacaggtgca
     6841 aatgataatt taaatggaga aaaggctgta agctttgata taccatttat gaataaaaat
     6901 gcagaaattg ttcaatcact tgcaaaatgg aaaagattag cccttaaaaa atatgggttt
     6961 gaagttggta gtggtttata tacagatatg aatgcaataa gaaaaaatga agaattagac
     7021 aatatacatt ctctttatgt agaccaatgg gattgggaat tggttataga taaaagtagt
     7081 agaaatgaaa agactctaaa agatgttgta aaaagattgt atggagtatt taaagatact
     7141 gaaatttttg tatgtagtat gtatgaaggt ataaaagaaa tattaccaga agaaataact
     7201 tttataacat cacaagagtt agaagatatg tatccagaat tatcaccgaa ggaaagagaa
     7261 gataaaattg taaaagagaa gaaagcagta tttataactc aaataggaaa aacattaata
     7321 tcaggagaaa aacatgatgg aagaagccct gattatgatg attgggaatt gaatggggat
     7381 atattatttt acaatcctgt tttagattca gcattagaat tatcttcaat gggaattaga
     7441 gttgatgaag aatctcttga tagacaattg aaacttgctg gatgtgaaga gagaaaagag
     7501 tttgactatc ataagatgct tttaaatggc gaacttccgt atacaattgg tggaggaatt
     7561 ggtcagtcaa gaatatgtat gtatttctta caaaaagctc atataggaga agtacaagtt
     7621 ggagtatggc cacaggatat gattcaaaat tgtagtagtg caggaattga attattataa
     7681 tttaaatata aactaattga taaaatttat atctaatatg ttcatcaaat taattatatc
     7741 ggttataatg tagaataacc tataattata agaggtgata aatatggagt ttttaaaaat
     7801 aatcattaat atagttttag atattttaaa aaaaattttg gtcagattta aaaatgctaa
     7861 atttggtttg gtttttgtat ttgatttact taaactacct gattttatga cagataaaag
     7921 aatcaatata gttgataaaa taaaggtaat ttctgtatta atttttacta tatcctactt
     7981 tgtatctggg gttgatataa ttccagagat gattgcaggg gcatttggtt ttatagatga
     8041 tgctatagtt ttaatttgga gtataggtat agtgaatgaa gaaattaata agtatagagt
     8101 tattataaaa aaagataaac attcaaatat aattgaaaat gtagaatttt ctataaaaga
     8161 tgaagaagaa taacaattta tatatgttat tctttttttt attaacaaaa aatggttaaa
     8221 ttgttgacgg agaggtaaaa ctctattatc ataataagtg gatatccaat atttaactaa
     8281 gtattcaatg tgcaagaatg cttaatttaa aaaagttatg gagggtaaat attatgaaga
     8341 aaaaaatagg tttagtgccc aaactaatca tcggtatcat agtcggtatt ttaatcggaa
     8401 gttatgcacc agaaataata gtacaaatat tagtaacagt tagtacctta ttctcagcat
     8461 tcctaaaatt tgttatacca tttataatta taggttttgt aacagcaggt atagctgatt
     8521 tagcaacagg tgcaggaaag ttattgggga taactacggg aatagcatat ggttctacct
     8581 taatagcagg attattatca tttgcagtat ctacattaat cttcccaaat tttattgatg
     8641 caagtgttgc aagtcaaatt ggagacccag aggcaggaat gttagctcca atattcacaa
     8701 ttccattaga gcctatggta gatgtaacag ctgcaatcgt atttgcattt gtaatgggac
     8761 ttggaatatc agctttaaga aatcatggaa aaggagagac tttatttaat ttcttccaag
     8821 aatttcaagg aatcgtaacg aaaacgttgt caacagtgat tataccttta ttacctttat
     8881 acatagcagg aacttttgca aatataacta tagcagggga agtatggaca atattagggg
     8941 tattctggaa agtatactta gtagtaatac ctttacattt tgtatatatg gcatgtcaat
     9001 tcacagcagc aggtgtattt tcaggaaaaa atccagtaag aatgttaaaa aatcaagtac
     9061 ctggatattt aacagctata ggaactcaat cttcagcagc aactatacca gttaatgttg
     9121 gttgtgcaga aaaaaatgga gtaagtaagc aaataagaga atttgttgta cctctttgtg
     9181 caacaataca tttatcaggt agtatgatat caataacagg atttacaact gcagttttaa
     9241 tgatgaatgg tatgccacat ggaataggtg tattattccc ttatattgca atgttaggta
     9301 tagcaatggt tgcagcacca ggagcaccag gtggggctat aatgagtgca cttcctttcc
     9361 taccaatggt tggaatacca tcagatggtg ggcttgcaag tttaatgata gctttatact
     9421 taactcaaga cagttttggt acagcatgta atgtatcagg agataatgca atagcagtag
     9481 tagtagataa aataaatgat ggaatgagta aaaaaggaaa caaagaagag caaagtgctt
     9541 agttttttaa taatcaaaaa tgagttatct caaatagaga tagctcattt tttatggtat
     9601 aaaaaaatta taaaataaag ggattttttt atttaaaaat tgctttaaga gatgatatta
     9661 ataatttatt ttcattaggt tttaatatac atactctaaa gaaatactca tctagacctt
     9721 caaatgaaca acaatctctt attattattt tttgtggaag cagttgttct cgaagcgatt
     9781 tagcagttaa ttcctttgtt ttgattttac acaatatgaa attaccttta gtattgtata
     9841 tatctaagct ttttatattc ttaagctctt taagcaggta atctctttca gtgttcatta
     9901 aggaaatagt atttgatata aaatctaaat cactaaacat gatttccccc attttagaag
     9961 ctattatgtt tatattccat aaatctagat ttttatttat ttcatttttg acattagtgt
    10021 tagatataag accatatcca agccttattc caggcgttga aaaaaatttt gatgtacctc
    10081 ttataacgaa taaattagaa taatcatcaa ctaattgagt acaagagtat gtatctgtat
    10141 cagtaaactc tacataagtc tcatcaatca ttaaaaatga gtctgtattt tttaaaattt
    10201 ctctcacttc tactttagta aatgcaaatc cagttggatt actaggatta cagattacta
    10261 ccaaatcata atctttagca ttgatagttt ttataagatt ttctaaattt atatgaaaat
    10321 tatcttcttc ttttgcaaag tatttttcta tagaacaatt aattttagat aactcttttt
    10381 catactctga ataggctgga gagagtaaaa gagcctgttt aggattaatt gtatgtataa
    10441 atgatgaaat tagttctgta gctccactgc caagtactat attatctata gaacatttgc
    10501 agtaattgga tatagaagtt tttaagtcta tgtaatcagg gtcaggatac atagatacca
    10561 tatctatatt gtttacaatg tattgtttgg ctaaacttga tgtaccaaaa ggatttatat
    10621 ttgagctaaa atccataaat tcttcctttg aaaagccata cttactagat aaactatata
    10681 aattagctcc atgatttgtg ctcataaaag tacctccaaa aataaaatta tataatcgat
    10741 aaaaataact gattaatata tgtacatata gattataata caaaggaatc gttattccaa
    10801 atttttaatg gaaaaagcaa aaaagtatgg ataagctgtt aatttaggtc taaaaatgat
    10861 gaaaaagatt ttaattgata ttttggtatg ctataatata taagttaata gaaggaaagc
    10921 gggaggatac aaaatgtaca aagttacagg aaaaatgttg acagaagaac aaataaaaga
    10981 aaaagtttat gaattaggaa aaaagataga agaagacttt aaaggcgaag atttactagt
    11041 ggtaggtata cttaaaggag ctagtgtatt tgtttcagat ttaataagat gtatagattt
    11101 ggatgtaaat atagatttta tgagtgttac aagttatgga aactcaacag agtcttctgg
    11161 aacagttaaa atattaaaag atttagatgt agatattgaa ggaaagaatg tgttgattgt
    11221 agaggatata atagattctg gtttaacatt aagtaatcta gttgcagctt taaaaactag
    11281 aaatccaaaa tctttaaaac tatgtactct acttgacaaa cctcagagaa gaaaagctaa
    11341 tatacctgta gactatgttg gatttgttat agaagacaaa tttattgttg gttatggaat
    11401 agactatgct gaaaagtata gaaatttacc ttatataggt atagttgagg atgtagaata
    11461 gatttaaatg tgaatcaaaa gcactaattt ctaagggagt tagtgctttt tagttaatta
    11521 tataaaattt tagtaaagga gacatctata tggatattca gttaaatata ttattatttt
    11581 tccaaaattt aagaaatcca attttgaact ttatatttct tgtctttaca ataagcacag
    11641 aagcaccgtt attaatatta attacaacaa ttatatactg gtgtataaat aaaaaatgtg
    11701 gacagaaaat actgtttgct ataattggaa attttgttgt aaatttaggc atcaaagagt
    11761 ttgtaaaagc tcccagacca ataggaataa aaggtcttga atcattgaga gtttctactg
    11821 ctggtggtta ttcttttcca agtgctcata ctcaaactgc aacaacattt tgggttagta
    11881 ttatgactat atttaaaaag agatatcttc atttaatagg tgcagttatg gttttaggag
    11941 taggattgtc taggctgtat ttagctgttc attggccaat agatgtgata gtgggttgga
    12001 tgttaggaat attttttaca gttatattta taaaaatatt tgactatatt gatgataata
    12061 aaaattatat tttacttgta gttttactta taccatttat aatagtagct atatttctaa
    12121 atagccctga atattttgaa aaatttggta taatagtagg atttgtattt ggatatatgg
    12181 ttgaggatag atttgttaaa tttaatacag ataataataa caaaaaaata aattttagca
    12241 ataaaaataa ggggagtaaa aatataattt tttcaagaat atgtaggttt ttggttggga
    12301 tagtaacaat aggaatgtta tatattggca ttaagttgtt tatttcaatg ttaatagtca
    12361 ctttaaatat aagtgactct actatgagta taatttttat gaattttatt aagaatacag
    12421 tagttgtttt ttatggaata gcaggagctc cagcattatt taaactttta aaattaaatt
    12481 gattttaagg tatagagtca atagtttaaa ttaaaaaaat taagggtaga aaagagtgat
    12541 tatttgaaga aggtagtaat aataggtggt ggaccagcag ggatgatagc cgcatcaact
    12601 gcatgtgaga aaggctatga tgtaacatta attgagaaaa atcataaatt aggaaaaaaa
    12661 cttgcaataa caggaaaagg tagatgtaat attactaacg cttgtgaaat agaggaatta
    12721 atagaaaatg tacctacaaa tggaaaattt ctttatagtg ctttttatac ttttacaaat
    12781 gatgatgtaa taagtatgtt taataatctt ggagtaaaga ctaaaacaga aagaggaaaa
    12841 agggtttttc cagagagtga taaagccttt gatattgtaa atgctcttga aagacaactt
    12901 aaaagtaaga aagtaaatat attattaaat tcaaaagtag aaaaaataat atctaaaaat
    12961 aataaaattg agaaagtaat tttaaacgat aaaaaagaaa ttaagtgtga ttcagttgta
    13021 gtagcaactg gtggattaag ttatccactt actggttcta ctggtgatgg atataaattt
    13081 gcaatttcac aggggcacac aattatagat acaaaaccat ctttaattgg tatagaagta
    13141 caagaaagtt ttacaaaaga tttagaaaaa ttatcattga gaaatgttga aataagggtg
    13201 tttaatagca aacaaaagaa agtttatagt gattttggag aacttgaatt tactagattt
    13261 ggtttagatg gacctataat caagtctgca agttgtagaa tgaaagatac aaggaaagaa
    13321 aattacacta tattattaga tttaaaacct gcattagatg aggaaaaact ggataaaaga
    13381 gttcaaaaag attttcagaa gtatacaaat aaaaaatttg aaaaagcatt agatgattta
    13441 cttccaaaaa aactaatacc tataataata aacttaagtg aaattaatgc aaatacggtt
    13501 gttcaccaaa tttctagaga gcagagaaaa aacttagtcc atttattaaa aaatttaaag
    13561 tttacagtaa agagatacag acctattgaa gaagctataa taacttctgg tggtgtaaaa
    13621 gtaaacgaaa taaattcaag cacaatggaa tcaaaattag tagaaggttt attttttgct
    13681 ggagaagtaa tagatataga tgcatataca ggtggattca atttgcaaat agctttttct
    13741 actggatatt tggcaggttt taattgctaa aaattacctg aattaaaaat gtttaaaatc
    13801 acataatatt atcagcaaca caaaataaat taaacagaag gaaggtaatc aacatggcaa
    13861 gtaacaataa caacaacaga acagtagtac caggagcaaa agaggcttta aaccaaatga
    13921 aattagaaat agctaatgaa cttggtatga gtaattatca acaagttgat aaaggaaacc
    13981 ttactgcaag agaaaatggt tatgtaggtg gatacatgac taaaaaatta gttgaaatgg
    14041 ctgaacaaca aatggctgga aaaagcaaca gatagttata aataattatt tataactatt
    14101 ggctattagt ttagctagag ctatctcaaa tatagaaagt aatttctaaa ttgagatagc
    14161 ttttttttat taaattatta aatagatata tttttatgta ataaatttta tgtatttgga
    14221 taaaataata caaatgaata tgttacataa ggagtgatgt aaaatgagta gtgtaaattt
    14281 tgaggattta aaaaacaaat ttattaatag tgacttagat gaaaaaataa gaatatatac
    14341 aacaacagaa ggtttatcag tagaacaatt taaagagcta ctaaaatatt atccaataca
    14401 acatttatct aaactagaaa aagcacttgg atagcagtat ttagtccaaa attaaaaagg
    14461 caatttattt aatattaaaa atatttttta ttaaataaat tgccttttta taataggttt
    14521 aaattattat gcttttgata tataattata gattctctca tttccaagtt caatagaccc
    14581 agtattaata agagtaacga ttccttctat atctctagca gttaagtatt tatatggaat
    14641 taataaatta taaccagtat tacttagtaa gttttttaat tgggttattt gagagatatt
    14701 gaaacatttt gcagttttag tagatttttt tcttaagtta gataaatttt cattttgaat
    14761 atttattaaa gtttctatat agtttctata agatatctta aaatttgtct cattgactat
    14821 tttttcatta agtatactac tgataaaatg ttgagacaat atattatctg caaatttatc
    14881 tgctgttaat tttccagatg ttatgccttt ttgatatttt ctaagaattt ttttagtata
    14941 gcagtatatt ttatttctcg tttctaaatc gagttgttct atttgcacaa aaccacttcc
    15001 ttctaattat aaaaatattt attaaaaatc tatacttaac taataaagct tcaataattt
    15061 atttacagta aatactaaat cataaaatat ttgttatttt ttattattac caagtataaa
    15121 aaatattata attgtaaaac ttacaaatat atgtaaaata tttaggagtg atgaaaatgt
    15181 taaatgggat aataaagctt ttttattctg aaattgtaaa aacaaagatt aataacctag
    15241 actcaagtgg atattcttta agagatgaat gtaaagaaat cagaaatata actctaaaga
    15301 tagatagcgt attttttaag cttttaaagt tggcttttgg ttcaatactg cttatgatag
    15361 cttttaattt aaacatgatt ctaggtatag gagtgttttt aattggtgta gtttatatac
    15421 tatataaaag aaatatggaa gaacaagtaa aagagcatat aaataatgtg aaaaataata
    15481 tcgacatctc taaaataact tttatggatg aaaaagggag aacaggtcta aatgcattga
    15541 ttacattact tcttatagga ttattgacag gatttaactg gatattagtt gctagttttg
    15601 tcgttgtttt tgtttttact ataaagaatg tatgttaaaa tactaataaa tagtttaata
    15661 tataggggga gaaattgagt atgactaatg gcagttataa aatgaagaat ttagtggaga
    15721 tatccgctat ggtgacggaa tctacagatt tttttaatat aaaagatgac ataatagaaa
    15781 aaatgttaga agttgttcac cctacaaagg catgtgtaaa tctattttat aaaaatgatt
    15841 ctaaatatgc ctacttagta tgttcgcaaa ccttagaata tgtacctcaa atttttccaa
    15901 taaatagtct taaaggtgca aaaattgatt ttgacacata tccagagtat atacatgagg
    15961 ctgtaaatga aaaaaagata atatatgtgg aaaatgtatt tgaagattct agagcagaag
    16021 gtgaacgaga tttagcaaaa gctgaaggtt atattgggag aatagttttt ccttttataa
    16081 taaataatgt agttgttgga tttatgactt gttttttaaa agaggatgat tatataacag
    16141 aacaagatat agattttata tcatctgttg catcactctt aagtttatca atagaaataa
    16201 ctaataaaaa taataatgta caaattttaa ttgataaact aagaggctca ataagtgcca
    16261 taaatgaagc tactaaaaaa ctatacctta ataagagtat tgatggcttt ttggaaaatt
    16321 taagtaaaca agcgtgtaat attactaata gtaaagaagc tttaataatt ataaatagtc
    16381 atcataataa ggatactata gttagttgtt ataatgttga gcaaaaaaag aaaacaaatt
    16441 tatatcctat gattgatatg tttttaaaga aagagtcatt agggggatac ctaaataatt
    16501 taaaaccatg ctcaaaaaag ggcataaatt tggaaagtta tatatattac aaacttcagg
    16561 ataaaaatga gactatagga tgtatagttt gtgcaaatag taaaaactat actagtgatg
    16621 atttaaatat tcttagtata ttgtccaaac aagtttctgt tgggatgcaa ttatatgaac
    16681 ataatgaaaa ggaagtaaaa cacaaagttc ttgaaaatga gttgaacata ttaaataaac
    16741 aacaacagct tattatggat aaaggtaaaa tggattgtaa tgatgagaaa gaactttatt
    16801 tttaccataa accagcaagg gtagtaggtg gagattttta ttatgctaca aaagtggatg
    16861 acgaacatat agtttatatt gttgctgatg taatgggaca tggaatggta tcaaattatg
    16921 ttgttgcaat gataaaaggt gcttttaaag tattatgcaa tcaatacaat acaccaagag
    16981 aaataatgac aaatttaaat aggatgttat atgatgaatt tgacaagatg ggagtattta
    17041 caacttgttt gataggtatt atagatacta aagaaaatat gattactgtg tctaatgcag
    17101 gtcactatag tcctgtagtt gtaaagaaag atggcacaat agaaaataat ttaaattgta
    17161 aaaagggcat acctattgga ataatgaaag atgctactta tgaaaataat actctttcaa
    17221 tggaagatta tgcaatggta tgtatgtaca ctgatggaat tttagagata aaaaattcat
    17281 caaaagaaga gtatggtata aacagattag aaaactttct aaaagaaaat tttagattaa
    17341 atcaacagtt aatagtagaa aatctaaaat tggatttaaa gaatttctca tcaaaagata
    17401 attatgatga tgatatttta atagttatgt taaaggatag gtagattgat tatggattca
    17461 aacgataaaa aaggacttaa aagtacagag attataataa taaatggaag tccaagaatt
    17521 aataaaaatt gcagttttat agcaaataaa gtaaaagcta tgctagaaga gtgtgggtta
    17581 agttgtaaaa tatttaatat ctacaatatg gatattgaat attgcacagc atgtggattt
    17641 tgtgaaaaaa cagggtattg caagtttaat gatgatatga agccattata taaaatgttt
    17701 gatgattcaa aaggaactat agtaataagt cctgtacatt ttgattcaat atcagctaaa
    17761 ttaaagactg ttgttgatag aactcaagct atatatgcaa gtaaatatgt attaaataaa
    17821 ccttcaattg atagaaataa gaaacggata ggaatgtata ttgcagtggg ggggagtaaa
    17881 tcatatgatt cacagtttaa aggtggacag attgttatgg attttttctt taagagtata
    17941 aatactaaac ttttacacaa tatatattta aacaatacag atgatgtatc ttatatagat
    18001 aatcaagaat ttaaagatat aatatataaa aatttaaaga tatatattga ttcaatataa
    18061 tttgattttg taggtaatat tatgtataat tgtattgcaa taatttaaat aattaaaagg
    18121 agggaatttc aatgaaatta ccaatagcat tatctaataa acatgttcat ttgagtcaag
    18181 ctgatataga cgtattattt ggggcgggtc atgagttaac taaatttaaa ccattatctc
    18241 aaccagggca atatgcctgt gaagaaaaag tggatttagt aggaccaaaa ggaactttaa
    18301 agggagttag agtactagga ccagctagag ctcatactca agttgaaata tctttagcag
    18361 atggtttccc attaggagta aaagcaccaa taaaagaatc tggtgatata gctggaactc
    18421 caggtgttaa attagtagga cctgctggag aagttgaaat gaaagaagga gttatagttg
    18481 cttctagaca tatacatatg agcaatgaag atgctgctaa atttggtgta actgataagc
    18541 aaatagtaaa agttaaaaca tctggaccaa gagcattagt atttgaaaat gtattagtaa
    18601 gagctagtga tagctttaat ctagaaatgc atgttgatat ggaagaggga aatgcagcag
    18661 gcgttaaaaa tggagattta gtagaattaa tagttgatta atattataaa tagactttat
    18721 gctagtagat attttatttg ctagcatatt tttaaatgta ataaatttct ataggataaa
    18781 tttaatcgat tagattaatt tataaaataa aggggtatta taaaaaatgt aataaaaact
    18841 tacaaaaata tgatg
//
LOCUS       DAMJYN010000071        18608 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.074, whole genome shotgun sequence.
ACCESSION   DAMJYN010000071 DAMJYN010000000
VERSION     DAMJYN010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18608)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18608)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18608
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.074"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            134..1051
                     /locus_tag="PC466_002758"
     CDS             134..1051
                     /locus_tag="PC466_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing protein"
                     /protein_id="HDF2770124.1"
                     /translation="MMILIQSRGKMKCKELSEELEVSERQIKSYKMYLEQAGIFINST
                     PGIYGGYEIDKCNSISLIKLLDSEVSILDMINSQLEYNNDIYKNEFNNIVEKIKAVLN
                     TGEKSDTYMDYFTVQAQRNCDYKSEKNKCNEIIRAYTTKHKFWIEYYSLNSGNSERIV
                     HPYGLFNYKSDTYMVAFCEKRFKFIDFKLCRIKDYKVLEEKYNVDKSFSWDEYSKNSI
                     GIYKGEEINVVIKISHPFSIIIKEKVWVNNQQIIEYDDKSIMFKAKMRGYEEIKSWIL
                     SMGAYVEVVEPDRLRNDILSEIEKMKKIY"
     gene            1129..1866
                     /gene="cas6"
                     /locus_tag="PC466_002759"
     CDS             1129..1866
                     /gene="cas6"
                     /locus_tag="PC466_002759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endoribonuclease Cas6"
                     /protein_id="HDF2770125.1"
                     /translation="MKMKIEFSTGCIPISYNSLFMSIIKEAIRKSNEDYYKNMYYYKE
                     KNNKKTKNFTFSVYIKKYSIEGDNFIIEDKVILNISTPDLELGFHIYNGLMTSKKCLY
                     KAYELTRIRIDLSREKKVTEERVLFNALSPICVKSKEGKFLEITDDRYIEELNYITNE
                     VVKNYRGNGLKRKLEFENIGLKKIVVKESLREFKKITGKEYQYINGYKGKFILKGDID
                     DLNLIYNLGIGFRRAQGFGDVDILEWR"
     gene            1872..3749
                     /gene="cas8a1"
                     /locus_tag="PC466_002760"
     CDS             1872..3749
                     /gene="cas8a1"
                     /locus_tag="PC466_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated protein Cas8b1/Cst1"
                     /protein_id="HDF2770126.1"
                     /translation="MKLRVYRGDWFFNMGIVGFLNIIKKADKQAEIFIMEDYIEFDSL
                     FLENFHEYYFNYFMDEYDVSKRIKKNIDYSINFIKSKPDRIKDGIKKIKDSVKQQNDK
                     IKKFDEEKFNLIKEKLDSMSKIKSYDEFDSLEALVDETIDIFKIKSINDRLTANLYKY
                     VVQDNYFGQVSFFNVAKAKLDLDGLKQIMFNDYLRQIIYFGELADLLEENDYDKLKNY
                     LNDRLNSIAKDINEKKVSKSSINTIEKIMKEINKNFIKKNKSIEDIKEYMDSLEVCEM
                     CGLYKGILDEYSESNFAPLGVSTNNARNMFWNQAYVPSICDICKLILFCTPAGATYTR
                     KNYLINEENEFYLFVNMDTSINELFERNNSLKAQKSEYSDSKDENPFNQLIKSIVEEN
                     TLKSEWQLRNILFVEFKASIDSKKCKINYFNIPTYLAKFFTDKYANKKIQSIYDYKLK
                     SNVLDLLLKNRDLKHLTNNILRNKVKNDMESNNKSNISGIDCFRVVQLRALINSYKKG
                     VYKMDSKNLEKNDEKLRIIYYLGCDIHDYFVNKNSKNKIDGVSYKLLNSVKVGNKSDF
                     MDTIIRVFMSAEKQIPAFILDIEIEKDLDFESIGHAFISGLISGKYEGKDKLPNEKEE
                     K"
     gene            3751..4665
                     /gene="cas7i"
                     /locus_tag="PC466_002761"
     CDS             3751..4665
                     /gene="cas7i"
                     /locus_tag="PC466_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated protein
                     Cas7/Cst2/DevR"
                     /protein_id="HDF2770127.1"
                     /translation="MKRGLTFTVIAQAQSLNYGEGIGNISELKKLSRDDGNIYTFASR
                     QCLRYDIVRLAAELFNWNLQVVDKEKGTIQFKDNISIRESEEMDLFGYMKTNKKDEKD
                     KKGGSLTREATVRLSNAISLEPYRSDMDFLNNKGLADRIGEHPNLANIEQHLSYYTYT
                     VTIDLSKIGKDGDIELDNKEKCRRVVEFLEIIKVLNRNIRGRQENLSPLFVVGGVYEI
                     ANPFFLGRIKLKGDKNGFKINKQAIEEVIQGTFLGKDLKEFTYVGMVDGVFINKEEFK
                     GLFEDNFLSVDKFFGQLVKEVKEYYGVN"
     gene            4667..5368
                     /gene="cas5b"
                     /locus_tag="PC466_002762"
     CDS             4667..5368
                     /gene="cas5b"
                     /locus_tag="PC466_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated protein Cas5"
                     /protein_id="HDF2770128.1"
                     /translation="MKVLKLDLFQETACYKKPFAMKITETYPLPPYSTINGLIHKILN
                     ATEYIPFNISVQGTYESIFNNYQTTYFYKKDSITSMPMNSHMLLNVNLIIHIGGDFDL
                     LEEIYDSLLNYDEHLSLGRKEDLVRINDIRFVEVNKFEVDEDIQLDDYENYKLSECNI
                     RMPIYIPKTSLQDTDIDGISYRLNNYYDNNAVEDKKRVWNKVDSYYVEDGNTISIGDI
                     LLDNEGDLLYFNNIN"
     gene            5379..7700
                     /locus_tag="PC466_002763"
     CDS             5379..7700
                     /locus_tag="PC466_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated helicase/endonuclease Cas3"
                     /protein_id="HDF2770129.1"
                     /translation="MLYAKSNPVETLREHTDELLKQMNVLRESYGKNINSLDFLEEEI
                     FWQLLDFVIEFHDIGKAFSPFQELIKSRMDTKINEPKIVTHLENNVGHNYLSPAFIDY
                     SYIDRKKNKELRAVLNQVIVYHHERDIFIDKDFKNLIQKILDEDLINKVYELQREFKV
                     RYPIKTEKLSKVYLQSVEKRIDKNHKYYNLYIMLKGILHRLDHSASAHEVVECNNVIN
                     IGEQTENYLMKEFGSLREAQSFAKSNRNKNIILIASTGMGKTETALIWIDKDKAFFTL
                     PLRVSINALFDRAKNIIGVGEANDTFLGLLHSTAIDYLEESNQENSSEIVDLAKLLSC
                     KLTFSTIDQIFKFPFLYRGYEKVYSTLAYSKVVIDEIQAYSPEIAAVLVKGIEMIHKI
                     GGRFMIMTATMPTIYIDELKKRGVMNSNLADLTCNTEKIRHCVSIVENSIDENLGKII
                     QSGMNKKVLVIVNTVKSAVEKYELIEEIVKPKGIDVNLNLLHSMYIQEDRAKLEKYIK
                     EFADSDSNGIWITTQLVEASLDIDFDELHTENSTLDSLFQRFGRCYRSREYEENSPNI
                     FIYTEKATGIGSIYDKDIVEKGLELLKTFINGKECVKMKEKYKVEMVKILYSKESLEG
                     TAFEKRFTSALNILDTITPYSLGSKDAQNILRNIEGYTVIPEDIYNKIEETLIKDYEE
                     LGQELINAYSNDDRQLINKIKSKRKKARREIIKKTVNLPIYKAKQNVIDIQVKGLEDL
                     KILLYKYDIHENKHTKQIFGKGVLISNEIDQFI"
     gene            7715..8266
                     /gene="cas4"
                     /locus_tag="PC466_002764"
     CDS             7715..8266
                     /gene="cas4"
                     /locus_tag="PC466_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated protein Cas4"
                     /protein_id="HDF2770130.1"
                     /translation="MWLKFTKEGDFVPIDLEVLKVQGVKINYYYVCKRKLWLFSKGIT
                     MEQNSSRVLSGKIVHEDSYKRMKNKEMLIDDILKLDIIKDEYVKEVKISSKMKEADEM
                     QLYYYLYYLKNSMGIEKKGTINYVKEKKQEELILTEEKEKIIENTLININEINMQLSP
                     PKIEKKHYCTKCAYYEFCFVKEE"
     gene            8269..9249
                     /gene="cas1b"
                     /locus_tag="PC466_002765"
     CDS             8269..9249
                     /gene="cas1b"
                     /locus_tag="PC466_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated endonuclease Cas1"
                     /protein_id="HDF2770131.1"
                     /translation="MYKDYYIISNGNIKRKENTIYYYNLEGEKKILPVEQVDDIHIYG
                     EVDLNTKLINYISKYGVMLHFYNYYGYYSGTYYPRKKNVSGFSLVCQSACYLDKNERL
                     YLAKSFVESASYHILRNMRYYKVDESLIDTIKDELNDLNDVKEISELMGKEGRIRKTY
                     YKSFNQILKDDFEFYKREKRPPKDPVNTLMSFGNSIMYTNVLSEIYKTQLDPTISFLH
                     EPSTKRFSLSLDIAEIFKPIIVDTIIFSLINNKRINKNDFEYQDKICYLSEKGKKKFL
                     QEFENKMQTTIKHRNLNRKVSYRMFIRLECYKLIKHFINDERYKVLKVWW"
     gene            9252..9518
                     /gene="cas2"
                     /locus_tag="PC466_002766"
     CDS             9252..9518
                     /gene="cas2"
                     /locus_tag="PC466_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endonuclease Cas2"
                     /protein_id="HDF2770132.1"
                     /translation="MFVIVTYDIVEARSLNRIRRILRKYLTWTQNSVFEGNITDGKLH
                     KCISEIENIIDNSEDSIYVYEIKNPNSIKKKCYGIDKYSDEMFI"
     repeat_region   9702..11319
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=9702..9730
                     /rpt_unit_seq="gttttatattaactaagtggtatgtaaat"
     gene            11509..11937
                     /locus_tag="PC466_002767"
     CDS             11509..11937
                     /locus_tag="PC466_002767"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HDF2770133.1"
                     /translation="MIKKLNNKDINKIMEIWEKSTIKAHDFISKEYWQNNYNTVKNEY
                     IPISDTFVYDDGDEIKGFISIIDKSFIGALFIEPKYQNLGIGGKLLDYATKKYKSLSL
                     AVYKDNKKAVVFYNKKGFNIVKEQVNEDSGFKEYIMEYSK"
     gene            complement(12393..13172)
                     /locus_tag="PC466_002768"
     CDS             complement(12393..13172)
                     /locus_tag="PC466_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770134.1"
                     /translation="MKVNENNINNIDEELDELSRKVYLESPDFWISISDKIIDKVFDE
                     MLLFFAVKYNYFNIVCFAIENNYLDLNMPSKNKKYTNIMEHLLDTSKQNEDKKIYNYL
                     LSLNKGNNLDERPILDELNCNISSDTFEKKDIYLPKYLCPSCNSNIFDTGYKVSNDIT
                     YKFSSKEAEPIEMSSEVSSIRCCNCDELLEDITLNKLYNLCKIQNCNNCGSNLTKVGI
                     IAKKKMNFDENTEKFKDVSTSYCCGNCDSEINLSQREHFKI"
     gene            13496..14041
                     /locus_tag="PC466_002769"
     CDS             13496..14041
                     /locus_tag="PC466_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HDF2770135.1"
                     /translation="MKNTKVNIQDLTKMSICVALLCISSYIYIPLPFTPAGVTAQTIM
                     INLIALILTPRQAFSTVGVYIMIGLIGIPVFGGGTSGIGKLLSPTGGFYFGFLFAALI
                     ISLLKGRNNDIKRYILITIFVGMPIIYFMGTVFMCYFNQMTVEAALFAAVVPFLIGDT
                     IKSVIASFLGTKLNNVLRRNL"
     gene            14073..15209
                     /locus_tag="PC466_002770"
     CDS             14073..15209
                     /locus_tag="PC466_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiolase family protein"
                     /protein_id="HDF2770136.1"
                     /translation="MKEVFILGGLRSHIGLKNGIFQFVQPELLGASVLKDLIKKYEID
                     KIDEIICGNAVGTGGNIARLMTLTAGVSNEVPAFTVDMQCASAMMSIDIAFSKVKSGQ
                     CNLIIAGGFESSSLQPMRTYHKNDKRYNTNNPNYTVAQFSPDDNSQNSMLEGAERVAE
                     LYQIERADLDFWVKESHKRAKEAREEKILEDIISPINNSTYDEGIRDKMSQRLLDRMP
                     PILGKETITNAANSCLINDGASFIIICSKKYLEHVKKKPKTKIINTCTIGTDATLSPT
                     SAIQAMDKLLEIESLNYLDVSAVEFNEAFAVIDVLFQRKYPELIERYNIFGGALAYGH
                     PYGASGAIITLHLLKALEKTKGRYGICSIAAAGGLGSALLLERV"
     gene            15213..16604
                     /locus_tag="PC466_002771"
     CDS             15213..16604
                     /locus_tag="PC466_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HDF2770137.1"
                     /translation="MNYYELLRIKKERHKNKNFLIIDGEKYTYENILSYSEQLGKQIS
                     LGENISILIYSKNIMFQLISFFAINYSKNIPIICHYNLSKKVLDDILLKNNISIIISD
                     ESMDVIDLYDDNNNEVAKKVNFSIFNPKFNLYMYQYKNLINYLDKSICMGALSSGSTS
                     VPKVLYRTYESWAGFFPIQNGIFNISGESILFVNGTLSFTGNLNSIMSVLYEGGSIVI
                     SSGLNCKSWIRTIKQYNVTNIYLIPTKLQLLVKHLKEPVLKVVSIFTGSQLLFEYTAR
                     NLKKYMPKSEIILYYGASELNYITYLCYDELIEKPLSVGRPFPGIDIYIRGGKIFVNT
                     EYAVYNATKPYSVNDIGYYDNDGYLIFEGRSDDIVNIGGFKVSSAKIENEVKKIPQIE
                     DAIVLPYSDTIRGNQIVLFVITIDKITKKDLLIKMKDNLMKNEIPKKIIFLNSFPYTS
                     SEKIDRLALLKML"
     gene            16680..17555
                     /gene="dpsA"
                     /locus_tag="PC466_002772"
     CDS             16680..17555
                     /gene="dpsA"
                     /locus_tag="PC466_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipicolinate synthase subunit DpsA"
                     /protein_id="HDF2770138.1"
                     /translation="MSNQYDITVIGGDLRQVYMVKKLINKGYSVVTYGISNEIINGIV
                     GKSTSLAEALSKSSIILCPIPFTKNQVNIENTDDCLDATIDNLLINLSPNQILFGGNI
                     PTKVCKFCEQHSIQIYDFMKMNDVAILNAVATAEGAIAEAIKRSIINIHQSNCLVLGY
                     GRCAQILAKKLYALDANVCVGARNNDARSTANAFGYSSISLSQLDEKLLQFDYIFNTI
                     PECILTKERLEKVSQEVTIIDIASSPGGVDYSVVKEVGINATLCLGLPGKYSPKTSGE
                     ILVNAIENIINERRD"
     gene            17558..18148
                     /locus_tag="PC466_002773"
     CDS             17558..18148
                     /locus_tag="PC466_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipicolinate synthase subunit B"
                     /protein_id="HDF2770139.1"
                     /translation="MRLEGLTIGVGFTGSFCTYDKIFIELENLVKEGANVHTIFSDVS
                     QNIDCRFGNSEEFMKKAYELTGNKPIVTIEEAEPFGPKGIADIIIIAPCTGNTAAKLA
                     NGITDSPVLMAAKGHLRNDKPLVISISTNDALSFNFKNIGILLNSKNIYFVPFGQDNC
                     KAKPNSMIAHTELIIPTIELALENKQLQPVIKSPHQ"
     gene            complement(18356..18556)
                     /locus_tag="PC466_002774"
     CDS             complement(18356..18556)
                     /locus_tag="PC466_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770140.1"
                     /translation="MKKLKTISIFSLIISVILTIGGIGIVTYYVDNLFIRGLSVFVLI
                     MSSSFVSTTVRLIFEESKRYKF"
BASE COUNT         7593 a         1805 c         3017 g         6193 t
ORIGIN      
        1 aattataaaa aaattctact tatataaaat ataaagaggt tatatgtaca tatgtgtaga
       61 aataaataat aaaaatatca attaatgtta ttaggggggg ttactcatta gtaaattagc
      121 taatacactt agaatgatga tattaattca aagcagaggc aaaatgaaat gcaaagaatt
      181 atcagaagag ttggaagtaa gtgaaaggca aataaaaagt tacaagatgt atttagagca
      241 agctggtata tttataaatt caacacctgg gatttatggt ggttatgaaa tagataaatg
      301 taatagcata tcattaatta aattattaga tagtgaagtt tcaattctag atatgataaa
      361 ttcacagtta gagtataata atgatattta caaaaatgaa tttaataata ttgtagaaaa
      421 aataaaagca gtattaaata caggagaaaa aagcgataca tatatggatt attttacagt
      481 tcaagcacaa cgtaattgtg attataagtc tgaaaaaaat aagtgtaatg aaataattag
      541 agcatatacc acaaaacaca aattttggat agaatattat tcattaaatt caggaaatag
      601 tgaaagaatt gttcatccat atggtttatt taattataaa tcagatactt atatggtagc
      661 tttttgtgaa aaaagattta agtttataga ctttaaatta tgtagaatta aagattataa
      721 ggttttagaa gaaaaatata atgtagataa aagttttagt tgggatgaat atagtaaaaa
      781 tagtatagga atttataaag gagaagaaat taatgttgtt ataaaaatta gtcatccatt
      841 ttcaataatt ataaaggaaa aagtttgggt taataatcaa caaatcatag aatatgatga
      901 taaatctata atgtttaaag ctaaaatgag aggttatgag gagataaaaa gttggatttt
      961 aagtatggga gcttatgttg aggttgtaga accagataga cttagaaatg atatattgtc
     1021 agagattgaa aaaatgaaaa aaatttactg attttttcaa ataatttata cttggaccaa
     1081 tatacttcac ggtctagtgt taatatatta attgagagag gtgatattat gaaaatgaaa
     1141 attgaattta gtacaggttg tataccaata tcttataatt cgctctttat gagtattata
     1201 aaagaagcaa taagaaaatc taatgaagat tactataaaa acatgtacta ttataaagaa
     1261 aagaataata aaaaaactaa aaattttaca ttttcggttt atataaaaaa gtatagtatt
     1321 gaaggtgaca attttattat agaagataaa gtaatattaa atataagtac tccagattta
     1381 gaattgggtt ttcatatata caatgggtta atgacttcta aaaaatgttt atataaagcc
     1441 tatgaactta caagaattag aatcgattta tcaagagaaa agaaggtaac agaagaaagg
     1501 gtactattta atgcattgtc tccaatctgt gtaaagtcta aagaaggaaa attcttggag
     1561 ataactgatg atagatacat agaagaacta aactatataa ctaatgaagt ggttaaaaat
     1621 tataggggaa atggattaaa aagaaagtta gaatttgaaa atataggtct caaaaagata
     1681 gtagttaaag agagcttaag agaatttaaa aaaataacag gtaaagagta tcaatatatt
     1741 aatggttaca aaggtaaatt tatattgaaa ggtgatattg atgatttaaa tcttatctac
     1801 aatctaggaa ttggttttag acgtgctcag ggatttggag atgtagatat tttagaatgg
     1861 aggtgagata aatgaagtta agagtttata gaggagattg gttttttaat atgggtatag
     1921 ttggattttt aaatataata aagaaagcag ataaacaagc tgaaatattt attatggaag
     1981 attatatcga atttgatagc ttatttcttg aaaactttca tgagtattat tttaattact
     2041 ttatggatga atatgatgta tcaaaaagaa ttaaaaaaaa tattgattac agtataaatt
     2101 ttattaaatc taagcctgat agaatcaaag atggaattaa gaaaattaaa gatagtgtga
     2161 aacaacaaaa tgataagatt aaaaaatttg atgaagaaaa atttaacctg ataaaagaga
     2221 agctagatag catgtctaag ataaaaagtt atgatgaatt tgacagttta gaagctttag
     2281 tagatgagac tatagatata tttaaaataa aatcaataaa tgacaggctt acagcaaatc
     2341 tttataaata tgtagttcaa gataattatt ttggacaagt tagttttttt aatgttgcta
     2401 aggcgaaatt agatttagat ggattaaaac agataatgtt taatgattat ttaagacaaa
     2461 ttatatattt tggagagtta gcagatttat tagaagagaa tgactatgat aagttgaaaa
     2521 actatttaaa tgatagatta aatagtatag ctaaggatat aaatgaaaaa aaagttagta
     2581 agtctagtat aaatactata gaaaaaatta tgaaggaaat aaataaaaac tttataaaga
     2641 aaaataaaag catagaagat ataaaagagt atatggatag tttagaagta tgtgaaatgt
     2701 gtggtttata taagggaata ttagatgaat actcagaaag taattttgct ccacttggag
     2761 taagcaccaa taatgctagg aatatgtttt ggaatcaggc gtatgtacca tcaatatgtg
     2821 atatttgtaa gctaatattg ttctgtactc cagcaggggc tacttataca agaaagaatt
     2881 atttaattaa tgaagaaaat gagttttatt tatttgttaa catggatact tctataaatg
     2941 agctttttga aagaaataat agtttaaaag ctcaaaaaag tgaatattca gattccaaag
     3001 atgaaaatcc ttttaatcag cttataaaaa gtatagtaga agaaaataca ttaaaaagtg
     3061 aatggcaact tcgtaatata ctttttgtgg aatttaaagc aagtatagat tctaaaaaat
     3121 gtaaaataaa ttattttaat attccaactt atttagcaaa attttttaca gacaagtatg
     3181 caaataaaaa aatacaaagt atctatgatt acaagcttaa atcaaatgta ctagatttac
     3241 tcttgaaaaa tagggacttg aagcatctaa ctaataacat tttaagaaat aaagttaaaa
     3301 atgatatgga aagcaacaac aaatcaaata tatcaggaat agattgtttt agagtagtcc
     3361 aattaagagc attaataaat agctacaaaa agggggtata taaaatggat agtaaaaatt
     3421 tggagaagaa tgatgaaaag ctgagaataa tttattattt aggttgtgat atacatgact
     3481 attttgttaa taaaaattct aaaaataaaa tagatggagt aagctataaa cttttaaatt
     3541 cagttaaagt cggaaataaa agtgatttta tggatacaat tataagagtt tttatgtcag
     3601 ctgaaaaaca gattccagca tttattttag atatagaaat tgaaaaagat ttagactttg
     3661 aatctatagg tcatgctttt atatctggat taatttctgg aaaatatgaa ggaaaagaca
     3721 aactaccaaa cgaaaaggag gaaaaataag atgaaaagag ggttaacatt tacagtaata
     3781 gcacaggctc aaagtttaaa ctatggggaa gggataggta atatatcaga attaaaaaaa
     3841 ttaagtagag atgatggaaa tatatataca tttgcatctc gccagtgttt aagatatgac
     3901 atagtacgat tagcagcaga attgtttaat tggaatttac aggttgtcga taaagaaaaa
     3961 ggtactattc aatttaaaga caatataagt ataagagaat cagaagaaat ggatttattt
     4021 ggatatatga aaacaaataa aaaagatgag aaagataaaa aaggaggttc tttgactaga
     4081 gaagctactg taagattaag taatgcaatt tcccttgagc catatagaag tgacatggac
     4141 tttttaaata ataaaggatt agcagataga ataggagaac atcctaatct tgctaacata
     4201 gagcaacatt taagttatta tacatataca gtgactatag atttatctaa aataggtaag
     4261 gatggagata tagaacttga taataaagag aaatgtagaa gagtagtaga atttttagaa
     4321 ataataaaag tattgaatag aaatattaga ggtagacaag aaaatttatc tcctctattt
     4381 gtagtaggag gagtatatga aatagcaaat ccatttttct tgggtagaat taaattaaaa
     4441 ggagataaaa atggatttaa aataaataag caagctatag aagaagtaat tcaaggtact
     4501 tttttaggaa aagatttaaa agaatttacc tatgttggaa tggtagatgg ggtatttata
     4561 aataaagaag aatttaaggg attgtttgaa gataattttt taagtgtaga taaatttttt
     4621 ggacaactag ttaaagaagt aaaggaatat tatggggtga attaatatga aggttttgaa
     4681 attagattta tttcaagaaa ctgcatgcta taaaaaacca tttgctatga agattacaga
     4741 gacatatcca ctgcctccat attctacaat aaatggatta attcacaaaa tattaaatgc
     4801 tacagaatat ataccattta atataagtgt acagggaaca tatgaaagta tatttaataa
     4861 ttaccagaca acatattttt ataaaaaaga tagtattaca tctatgccaa tgaatagtca
     4921 tatgctattg aatgtaaatt tgataattca tataggtggg gattttgatt tattggaaga
     4981 aatatatgat agtttattaa attatgacga gcacttatca ttaggtagaa aagaagattt
     5041 agtaagaatt aatgatatta gatttgtaga agtcaataaa tttgaagtag atgaggatat
     5101 acaattagat gattatgaaa attataagtt atcagaatgt aatataagaa tgcctatata
     5161 tataccaaaa acaagtttac aagatacaga tatagatggt ataagttaca gactcaataa
     5221 ttactatgat aataatgctg tggaagataa aaaaagggtt tggaataagg tagatagtta
     5281 ttatgttgag gatggaaata ctatatcaat tggagatata ttattagata atgaaggaga
     5341 tttattatat tttaataata taaattagga gggagagtat gttatatgct aaatctaatc
     5401 cagtggaaac acttagagaa catactgatg aacttttaaa acaaatgaat gtattaagag
     5461 aaagttatgg aaaaaatata aatagcttag attttctaga ggaagagata ttttggcaat
     5521 tacttgactt tgttatagaa tttcatgata ttggaaaagc attttcaccg tttcaagagt
     5581 taataaaaag cagaatggat actaaaataa atgaacctaa aatagtaact catttagaaa
     5641 ataatgtagg ccataattat ctttctcctg catttattga ttatagttat atagacagga
     5701 aaaaaaataa agaacttaga gcagtattaa atcaagttat tgtatatcat catgaaagag
     5761 atatctttat agataaagat tttaaaaatt taatacaaaa aatattagat gaagatttaa
     5821 taaataaagt ttatgaacta cagcgtgaat ttaaagttag atatccaata aaaacagaaa
     5881 aattgagtaa agtatatcta caaagtgtag aaaaaagaat agataaaaat cacaagtact
     5941 ataatttata tattatgtta aaaggaatac tacatagact agaccatagt gcttctgctc
     6001 atgaagttgt ggaatgcaat aatgttataa atataggaga acagacagaa aattatttaa
     6061 tgaaagagtt tggtagtttg agagaggctc aatcatttgc taaatctaat agaaataaga
     6121 atataatact gattgcatct acaggaatgg gaaaaacaga aactgctttg atttggatag
     6181 ataaggataa agcatttttt acactaccat taagagtaag tataaatgca ttatttgata
     6241 gggctaaaaa tataattgga gtaggagaag caaatgatac attcttaggt ctgttacatt
     6301 caacagcaat agattattta gaagaaagta atcaggaaaa ttcaagtgag attgtagatt
     6361 tagcaaagtt attatcttgt aaactgacat tttccacaat agaccaaata tttaaatttc
     6421 cttttttgta tagaggctat gaaaaagtgt actcaacatt agcatattca aaagtagtaa
     6481 tagatgagat acaagcatat tcaccagaaa tagcagctgt attggtaaaa ggtatagaaa
     6541 tgatacataa gataggtggc agatttatga taatgacagc tactatgcca accatatata
     6601 tagatgaatt aaaaaaaaga ggtgtaatga atagtaactt agctgacttg acatgtaaca
     6661 cagaaaaaat aagacattgt gtgtctattg tagaaaattc aatagatgaa aacttaggta
     6721 aaataataca aagtggaatg aataaaaaag ttcttgtaat agtaaataca gttaaaagtg
     6781 ctgtagaaaa atatgagtta atagaagaaa tagttaaacc aaaaggaata gatgtcaact
     6841 taaatctttt acattctatg tatatacaag aagatagagc aaaattagaa aaatatataa
     6901 aagaatttgc agatagtgat agtaatggta tttggattac tacacaatta gtggaagcat
     6961 cccttgatat tgattttgat gagcttcata cagaaaattc aacacttgac agtctatttc
     7021 aacgatttgg tagatgttat agaagtcgtg agtatgaaga aaatagccca aatatattta
     7081 tatatacaga aaaagctaca ggaataggta gtatttatga taaggatatt gtagaaaaag
     7141 gacttgagct actgaaaact tttataaatg gaaaagaatg tgtgaagatg aaagaaaaat
     7201 ataaggtaga aatggttaag atactatact ctaaagaaag tctagaaggt acagcttttg
     7261 aaaagagatt taccagtgct ttaaatattt tagatactat aacgccatat agtttaggtt
     7321 ctaaagatgc acaaaatata cttagaaata ttgaaggata tacagtaatt ccagaggata
     7381 tatataataa aattgaagaa actttaatca aagattatga agagttggga caagagctta
     7441 taaatgcata tagtaatgat gatagacaat tgataaataa aataaagtct aagagaaaaa
     7501 aagcaagaag agagataatt aaaaaaactg taaatttacc aatatataaa gctaaacaaa
     7561 atgtaattga catacaggtg aaaggtcttg aagatttaaa aatactttta tataaatatg
     7621 atatacacga aaataagcat acaaaacaga tatttggtaa aggtgtgctt ataagtaatg
     7681 aaatagacca atttatttga tttttatatt aacaatgtgg ctaaaattta ctaaagaagg
     7741 tgattttgtg ccaatagatt tagaagtatt aaaagttcaa ggcgtaaaaa taaattatta
     7801 ttatgtatgt aaaagaaaac tatggctatt ttctaaagga ataactatgg aacaaaatag
     7861 tagtagagta ttgtctggaa agatagtaca tgaagattca tataaaagaa tgaaaaataa
     7921 agaaatgttg attgatgata tcttgaagct agatataata aaggacgagt atgtaaaaga
     7981 agtaaaaata agttcaaaga tgaaagaagc agatgaaatg cagttatact attacttata
     8041 ctatttaaag aatagtatgg gtatagagaa aaaaggaact ataaattatg ttaaggaaaa
     8101 gaaacaagaa gaattgatat tgacagaaga aaaagaaaaa attattgaaa acacacttat
     8161 aaatataaat gaaataaata tgcagttatc tcctcccaaa attgagaaaa aacattattg
     8221 tacaaaatgt gcttattatg aattttgttt tgtgaaggag gagtaacaat gtataaagac
     8281 tattatatta taagtaatgg aaatataaaa aggaaagaaa atacgattta ctattacaat
     8341 ttagaaggtg agaaaaaaat attaccagta gaacaagttg atgatattca tatatatgga
     8401 gaagtagatt taaacacaaa acttataaat tacataagta aatatggggt gatgcttcat
     8461 ttctacaatt actatggata ttattcaggt acatattatc caaggaagaa aaatgtatca
     8521 ggattcagtt tagtatgtca atcagcctgc tatttagata aaaatgaaag attatactta
     8581 gcaaaatcct ttgtggaaag tgcatcatac catattttaa gaaatatgag atattacaaa
     8641 gttgatgaaa gtttaattga tactataaag gatgaactaa atgatttgaa tgatgtcaaa
     8701 gaaatatcag aacttatggg taaagaaggc agaataagaa aaacatacta taaatcattt
     8761 aatcaaatat taaaagatga ttttgaattt tataaaagag aaaaaagacc tcccaaagac
     8821 ccagtaaata ctcttatgtc ttttggaaat agcataatgt atacgaatgt tttaagtgag
     8881 atatataaga cacaacttga ccctacaata agctttttac atgaaccatc aacaaagaga
     8941 ttttctttaa gtttagatat tgcagaaatt tttaagccaa ttatagttga cacaataatt
     9001 tttagcctga ttaataataa aagaattaat aagaatgatt ttgaatatca agacaaaatt
     9061 tgttatttaa gtgaaaaagg aaagaagaaa tttttgcaag aatttgaaaa taagatgcag
     9121 acaactataa aacatagaaa tctaaataga aaagtttcat atagaatgtt tataaggtta
     9181 gagtgttata aattaattaa acattttata aatgatgaaa ggtacaaagt tttaaaggtg
     9241 tggtggtaag tatgtttgtt attgttactt atgatattgt tgaagcaagg tcgttaaata
     9301 gaattagaag gatacttaga aaatatttga cttggacgca aaattctgtt tttgaaggca
     9361 atattactga tggaaagtta cataaatgta tttctgaaat agaaaatatt attgataata
     9421 gcgaggattc aatctatgtt tatgagataa aaaatcctaa ttcaattaaa aagaaatgtt
     9481 atgggattga taagtattct gatgaaatgt ttatataggt ttgcagtgag cgatatttat
     9541 gctaaaatag gtgttaacag ttggaatata agggattgaa ggtgtatgat aactgttatc
     9601 aattgcacta ctgctcgctc actgcaaatt ttgatgtttt tattgaatta taattgcttg
     9661 attgaagtat tttcaatgta ttcaattata cctattttgg ggttttatat taactaagtg
     9721 gtatgtaaat aagcaactat agtagaagca aaagcgacaa caactaaagg ttttatatta
     9781 actaagtggt atgtaaattt ggttaactta agtgctatga aaggaattaa tgaagtttta
     9841 tattaactaa gtggtatgta aatttaaagg tgcaagtctt aatacttgtt acatgagttg
     9901 ttttatatta actaagtggt atgtaaataa caaagaacca tttgaatcac gaaaactaaa
     9961 aaacagtttt atattaacta agtggtatgt aaatttatta accttatcag aaacctgacc
    10021 atcccaatta tagttttata ttaactaagt ggtatgtaaa ttccatttgt ctaatgcttc
    10081 taactctttt tttatacgtt ttatattaac taagtggtat gtaaattcca aaatgggctt
    10141 ggagttaaga gttgtataag aaacgtttta tattaactaa gtggtatgta aattaattac
    10201 acactccctt ttaacgaaca tattttagat tgttttatat taactaagtg gtatgtaaat
    10261 agactcgaca tagaatcggt tactaaatcc gagggtttca ggttttatat taactaagtg
    10321 gtatgtaaat actaaacctt tttgtttact tttatttctc attttacgtt ttatattaac
    10381 taagtggtat gtaaatccgg atttttctgc ttcgactgtt gttattgaga cttgttttat
    10441 attaactaag tggtatgtaa atagtaattc catgcaatct tttatattgc tttttaacct
    10501 gttttatatt aactaagtgg tatgtaaata gatatacaag gtgaaagtgt tgaaatttca
    10561 atcttgtttt atattaacta agtggtatgt aaatattctt agatgttata atttgtgttg
    10621 catttaaatc gttttatatt aactaagtgg tatgtaaata caatattatt gttcatttca
    10681 tttaataatt ctagtagttt tatattaact aagtggtatg taaatttgtt tataccttta
    10741 atctttaaaa ttaaatataa aagttttata ttaactaagt ggtatgtaaa tcattgtata
    10801 ctaagcttga tatagtgcaa aatgaaacgt tttatattaa ctaagtggta tgtaaatact
    10861 aattgggtta aacaaatgga tataactaaa ttagttttat attaactaag tggtatgtaa
    10921 atccaaccct tcgcacgaat ccgtgcgacg aaatataaag ttttatatta actaagtggt
    10981 atgtaaattg taaaaatatt gcttagcata ttgatatcac taactgtttt atattaacta
    11041 agtggtatgt aaatacaaga ggtttttcag caatatatgt acttctataa tgttttatat
    11101 taactaagtg gtatgtaaat tcatcaatat taattttggg aatatcaaca ttttttgcgt
    11161 tttatattaa ctaagtggta tgtaaatgcg ataagagatt cgagtctttt tactgggctt
    11221 aatcgtttta tattaactaa gtggtatgta aataggataa agaaaagact cacacaagac
    11281 acagtgtcag gttttatatc aactaagtgg tagataagta gaatattagc aatatcaacg
    11341 agtatttaga aacttatttt atattaataa agcagtatat aaaattgtag aataaacaat
    11401 agcatatact aaaacatcca ccttatatta actaaatcat atctaaataa aatgcactta
    11461 cctataaaca ttataaaatc aatacaaaaa tgaggtgaaa caaaatttat gataaagaaa
    11521 ttaaacaata aagacataaa taaaatcatg gaaatatggg aaaaaagtac aatcaaagca
    11581 catgacttta taagtaaaga atactggcaa aataactaca atactgttaa aaacgaatat
    11641 atacctatat cagatacatt tgtatatgat gatggagatg aaataaaagg atttataagc
    11701 ataatagata aaagctttat aggagcttta tttatagaac ccaaatacca aaatctaggt
    11761 atcggaggta aacttttaga ttatgcaact aaaaaatata aaagtctaag tttagcagta
    11821 tataaagata ataaaaaagc agttgtgttt tataataaaa aaggttttaa tatagtaaaa
    11881 gaacaagtaa atgaagattc aggatttaaa gagtacataa tggaatatag taaataatat
    11941 gattacattc tattaaaaga ataattaatt tattttctat ttgattttta taagagtaat
    12001 ttttaaaata gactatatga agataaagat atttattata gatgtaagtt aatcagaatt
    12061 gatatagcta caaaagagga aaataaaatt gtatggtgta tttcagattt aacaaattta
    12121 ctatttaaag ataataagtt tgatataata ttaaagatac tttcacctat aaactatagg
    12181 gtatttgaaa gaattttgaa taattatgga atgctaataa aggtttgtta aaatttaata
    12241 attattagat tatagaaaat tgccatgaaa ttagttcagc aagaactagt ttcatagcaa
    12301 ttttaattct tataagtgta tttattttta cagatttaaa aaacttatac agtatctaat
    12361 aatgtaatct tattacttta gcctataaat atttaaatct taaaatgttc tctttgagat
    12421 aagtttattt cagagtcaca atttccacaa cagtaagatg ttgagacatc tttaaatttt
    12481 tcagtattct catcaaagtt catttttttc tttgcaataa ttcctacctt agttaaatta
    12541 gaaccacaat tattacagtt ttgaatttta cataggttat atagtttatt aagtgtaata
    12601 tcttctaata attcatcaca attacaacat ctgatagaag aaacttcact agacatttca
    12661 ataggttcag cttctttaga agaaaattta tatgttatgt catttgatac tttataacct
    12721 gtatcaaata tattagaatt acaacttgga cataagtact ttggaagata tatatctttt
    12781 ttttcaaaag tatcactact aatattacag tttaattcat ctaaaattgg tctttcatct
    12841 aggttattac ctttatttaa gcttagaaga taattataaa tttttttatc ttcattctgt
    12901 tttgatgtat ctaacaaatg ctccattata ttagtgtatt ttttgttttt tgaaggcatg
    12961 tttaaatcca gataattgtt ttcaatagca aagcatacta tattgaaata gttatattta
    13021 actgcaaaaa ataataacat ttcatcaaat actttatcta ttattttgtc agaaatactt
    13081 atccaaaaat ctggtgactc taagtaaact ttcctactaa gttcatctaa ctcttcatct
    13141 atattattta tattattttc attaactttc atatcatcac ttccttttaa atatcttgtg
    13201 tataaactat ttgttactat tttttatata aaataaaatc ttatataaaa atatatcata
    13261 ttataattta caagtatagt ctaaatagag ctgtttttaa gcaaagtttt ataaatgact
    13321 attaaaatat aaagtaacag tataaagttt acttataaat taaacgtaaa cctaaatact
    13381 tgtaatggtt gacaaaaaaa cgtctttatt ttatactaaa acaaagcttt aatagaggct
    13441 ttgtatatgt acatataaac taaatgaaat aagacatatg aagggaatta taaaaatgaa
    13501 aaatactaaa gtaaatattc aagatttaac taaaatgtca atatgtgtag cattattgtg
    13561 tatatcatct tacatatata taccattgcc atttactcca gcaggagtaa cagcacaaac
    13621 aataatgata aatttgatag ctttgatttt aacaccaaga caagcattta gtacagttgg
    13681 tgtatatata atgataggtt taattgggat tccagtattt ggtggaggta catctggtat
    13741 tggaaagttg ttaagcccaa caggtggttt ttattttggg tttttgtttg cagcactaat
    13801 tattagttta ttaaaaggac gaaataatga tattaagaga tatatactaa taacaatttt
    13861 tgttggaatg cctattatat attttatggg aacagtattt atgtgctatt ttaatcaaat
    13921 gacagtagaa gcagcacttt ttgcagcagt agtaccattt ttaattggag atacaataaa
    13981 gtcggttatt gcatcttttt taggcactaa actgaacaat gtactcagaa gaaatctatg
    14041 ataaatctat aatataagga agggtgtaat gtatgaagga agtttttata ttaggaggat
    14101 tgagaagtca tataggtcta aaaaatggaa tttttcaatt tgttcaacct gaattactag
    14161 gagcaagtgt tttaaaagat ttaattaaaa agtatgaaat tgacaaaatt gatgagatta
    14221 tatgtggaaa tgcagttggg acaggaggga atatagccag attaatgact ttaacagcag
    14281 gagtgtcaaa tgaagtacct gcttttactg tggatatgca gtgtgcttct gctatgatga
    14341 gtatagacat agctttttca aaggttaaat ctggtcagtg taatttaatt attgcaggtg
    14401 gttttgaaag tagttctcta caaccaatgc gcacatatca taagaatgat aagcgatata
    14461 atacaaataa tccaaattat acagttgctc aattttctcc tgatgataat agtcaaaata
    14521 gtatgctcga aggggcggaa agagtagcag agttatatca aattgagaga gcagacttgg
    14581 atttttgggt aaaggaaagt cataaaagag caaaagaagc aagagaagaa aaaatacttg
    14641 aggatattat atctcctata aataatagta cctatgatga aggtatacgt gataagatga
    14701 gtcaaaggtt attagatagg atgccaccaa ttttaggaaa agaaactatt acaaatgcag
    14761 caaattcatg tcttattaat gatggagctt catttattat aatatgttct aagaagtatt
    14821 tagaacatgt aaaaaagaag cctaaaacaa aaattattaa tacatgcaca ataggaacag
    14881 atgcaacctt aagtccaaca tcagcgatac aagcaatgga taaactttta gagatagaaa
    14941 gccttaatta tttagatgta tctgctgttg aatttaatga agcatttgca gttatagatg
    15001 tgttgtttca aagaaagtat ccagagttaa tagagagata taatatattt ggtggagctt
    15061 tagcgtatgg acatccatat ggtgcttcag gtgcaattat tacattacat cttttaaaag
    15121 cattagaaaa aactaagggt agatatggaa tttgctctat agctgcagct ggtggtctag
    15181 gttcagcttt actgcttgaa agggtgtaga ttatgaacta ttatgaactt ttaagaataa
    15241 aaaaagagag gcataaaaat aaaaattttt taattataga tggagaaaaa tatacttatg
    15301 aaaatatatt aagttatagt gagcaactag gaaaacaaat ttctttaggt gaaaatatct
    15361 caattttaat atattctaaa aatataatgt ttcagttgat tagttttttt gctattaatt
    15421 attcaaaaaa tattcctatt atttgtcatt ataatctttc taaaaaagta ttagatgata
    15481 ttttattaaa aaataatatt tcaatcatta tatctgatga atctatggac gttattgatt
    15541 tatatgatga taacaataat gaagtagcaa aaaaagttaa tttttctatt tttaatccta
    15601 aatttaatct atatatgtat caatataaga accttataaa ttatttagat aaaagtattt
    15661 gtatgggagc tttatcttca ggttctacaa gtgttccaaa ggtattatat agaacatatg
    15721 agagttgggc tggatttttt cctatacaaa atggtatttt taatatctct ggggaatcaa
    15781 tcttgtttgt taatggaaca cttagtttta cagggaatct aaattctata atgtcagtat
    15841 tatatgaagg aggtagtatt gtaataagtt caggtcttaa ttgtaaatca tggataagga
    15901 caataaaaca atataatgta actaacatat accttatacc tacaaaactt caacttttgg
    15961 ttaaacactt aaaagaacca gtactcaaag tagtaagtat ttttacaggg tctcaattat
    16021 tatttgaata tactgcaaga aatctaaaaa aatatatgcc aaagtctgaa attattttat
    16081 actatggggc aagtgaatta aattatatta catatttatg ctatgatgaa ctaattgaaa
    16141 aacctctaag tgtaggcaga ccatttccag gaatagatat atatattaga ggaggaaaaa
    16201 tttttgtgaa tacagaatat gcagtatata atgcaaccaa accttattct gtcaatgata
    16261 ttggatatta tgataatgat ggatacttaa tatttgaagg aagaagtgat gacattgtaa
    16321 atattggagg atttaaagtt agttctgcta agattgaaaa tgaagttaaa aaaattcctc
    16381 aaattgaaga tgcaattgta ttgccgtact cagacactat aagaggaaat caaattgtat
    16441 tatttgtaat aactatagac aaaattacga agaaagattt gttgattaaa atgaaagata
    16501 atctaatgaa aaatgaaatc ccaaagaaaa ttatcttttt aaattcattt ccatatacct
    16561 cttctgaaaa gatagataga ttagcattat taaaaatgtt ataagtataa tatttagtaa
    16621 ttttagtgaa ccaatgtatt gataaaaaca tattgtatat agtaaaggag gcttacaata
    16681 tgtcaaatca atacgatata actgttattg ggggagacct gcgacaagtg tacatggtaa
    16741 aaaaactaat taataaaggg tattctgtag tcacttatgg gatatcaaat gaaattataa
    16801 atggaatcgt tggaaaatca acttcactag ctgaagcact atccaaaagt tccattattt
    16861 tatgtccaat tccatttaca aagaatcaag ttaatattga aaatacggat gattgtcttg
    16921 atgctactat tgataacttg ctaattaatt tatctcctaa tcaaatatta tttggaggta
    16981 acataccaac taaagtttgt aaattttgcg agcaacactc tattcagatt tatgatttta
    17041 tgaaaatgaa tgatgttgct attttaaatg cagttgctac agctgaaggg gctatagcag
    17101 aagctattaa aagaagtata atcaatatac atcaaagtaa ctgtttagta ttaggttatg
    17161 gaagatgtgc acaaatactt gcaaaaaaat tatacgcttt ggatgcaaat gtatgcgttg
    17221 gtgcaagaaa taatgatgca agaagtacgg ctaatgcatt tggatattcc agtatttctt
    17281 taagtcaact tgatgaaaaa cttttacaat ttgattatat ttttaacacc ataccagagt
    17341 gtattttaac gaaagaaaga ttagaaaaag tatcacaaga agtaactatt atagatatag
    17401 cttcttctcc tggaggagta gattattctg ttgttaaaga agtagggatt aatgcgactc
    17461 tttgccttgg gcttcctggt aaatattcac caaagacatc tggtgagatt cttgttaacg
    17521 ctatagaaaa tattataaat gaaagaaggg attagaaatg agacttgaag gacttacaat
    17581 tggagtagga tttactggtt cgttttgtac ttatgataaa atatttatag agttagagaa
    17641 tttggttaaa gaaggagcta atgtacacac tatattttca gatgtatcac aaaatatcga
    17701 ttgtagattt ggaaattctg aagagtttat gaaaaaagca tatgaactta caggaaataa
    17761 acctatagtt acgattgaag aggcagaacc atttggacct aaagggattg ctgatattat
    17821 aataatagct ccttgtactg gaaatactgc tgcaaaatta gcaaatggta ttacagattc
    17881 accagtatta atggcagcaa aaggtcatct tcgtaatgat aaaccactag taatatcaat
    17941 atcaacgaat gatgctctaa gctttaattt caaaaatatt ggtattctcc ttaattctaa
    18001 aaatatatat tttgtacctt ttggtcaaga taattgcaaa gcaaagccta attctatgat
    18061 tgcacatact gagctaataa ttccaactat agaacttgct ctagagaaca aacagctaca
    18121 gcctgttata aaaagtccac atcaatagaa ttggttctta taatattatg tattagatac
    18181 aatactagca aagaggctgt ctcaaaatag agagaagcct ctttttcatt gttgaaatga
    18241 tgaaaatata tttaatttca tacaaaaaaa tgcatcatga actaaaaagt ctattttgag
    18301 ctaatctccg taatttttgg tatattaaaa ttatttactt aatccaattt ttaaattaga
    18361 atttatatcg ttttgactct tcaaatatca atctaactgt tgttgataca aaagaagagg
    18421 acataattaa aacaaatact gatagtcctc taataaacaa attatctaca taataagtta
    18481 ctattccaat acctccaatc gttaaaatta cacttataat caaagaaaaa atgctaattg
    18541 tttttaattt tttcatgctt atcctccttc ttataaactt caaatttatc tatataatat
    18601 taaatata
//
LOCUS       DAMJYN010000072        18509 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.075, whole genome shotgun sequence.
ACCESSION   DAMJYN010000072 DAMJYN010000000
VERSION     DAMJYN010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18509)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18509)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18509
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.075"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            69..224
                     /locus_tag="PC466_002775"
     CDS             69..224
                     /locus_tag="PC466_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770141.1"
                     /translation="MKGILKELTAKLYSFFYFMFWGFYFSAGYFFYKNICTSFLVRPY
                     FSDFEHK"
     gene            354..1367
                     /gene="aroF"
                     /locus_tag="PC466_002776"
     CDS             354..1367
                     /gene="aroF"
                     /locus_tag="PC466_002776"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003452924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HDF2770142.1"
                     /translation="MIVVLKMGADKNEVKKLIEAIGREGVEVNPIDGTELTVLGLVGD
                     TSKIDAKRIEANKIVEKVMHVVEPFKKANRKFHPEPSIINVNGMEIGSKKIAMIAGPC
                     SVETEDQIVSIAKDVKKSGAGFLRGGAFKPRTSPYAFQGLKYDGLDLLKKAKEKTGLP
                     IVTEIMSTQDIDIFEENVDVIQVGARNMQNFDLLKELGKTNKTILLKRGLSATIEEWL
                     MSAEYIMAGGNENVVLCERGIRTFETYTRNTLDLSAILAVKKLSHLPVIVDPSHAAGK
                     SWMVDSLSKAAIAVGADGLIIEVHNDPAHALCDGKQSIKPNEYDELISELKTIASAVG
                     REI"
     gene            1389..2453
                     /locus_tag="PC466_002777"
     CDS             1389..2453
                     /locus_tag="PC466_002777"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HDF2770143.1"
                     /translation="MEEKLLVNLKENSYNIFIKKNILKNIGEEIKKIYFGNKIFIVTD
                     ENIAKLYLDKVKNNLSESGFEIKSLILKSGEETKSFNTLPKIYDSLLDFKLTRKDLII
                     TLGGGVIGDLGGFAAATFLRGISFIQIPTSLLAQVDSSVGGKVGVDLERGKNLVGSFY
                     QPKAVFIDPNVLLSLPEKFYRDGMAEVIKYGCIKDKTFFNKLLSLKNREEVMQHIEYI
                     IHKCCFIKKTVVEADEKDFGDRMLLNFGHTLGHAIEKYYNFTGYTHGEAVAIGMYKIT
                     LESEKIGITKKGTSELIKSILMNYNLPYEIELRDNKSIVDAISLDKKNLGDTLKIILL
                     KDIGESIIYNTTSKFFQEVR"
     gene            2453..3766
                     /gene="aroA"
                     /locus_tag="PC466_002778"
     CDS             2453..3766
                     /gene="aroA"
                     /locus_tag="PC466_002778"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HDF2770144.1"
                     /translation="MGSLKIYPSKLSGDVKIPPSKSMAHRAVICSSLSNGKSRISNID
                     FSDDIIATIRAMTSLGAIIEKKEDILEISGIFSKEGILNRENQLNQPKLTIDCNESGS
                     TLRFLVPISLAFDGVKRFIGRGNLGKRPLDTYYEIFDRQNIKYSYKENQLDLIISGKL
                     KPDEFRVKGNISSQFITGLLFILPTLESDSKIIITTELESKGYLDLTLSTIKDFGVEI
                     INNNYKEFIIKGNQTYKARDYKVEGDYSQGAFYLSADAIGEDISILDLKEDSLQGDSE
                     VVEILSRMGMEILREGNKIKGITNGLNSTLIDASQCPDIIPVLSVVASLSIGRTTIIN
                     AGRLRIKECDRLHAINVELSKLGANIEEKEDSLIIEGVSKLNGGVEVWSHKDHRIAMT
                     LAIASCRCDKPIILKDFECVSKSYPHFFKDFKMLGGRIDEWNMGK"
     gene            3744..4823
                     /gene="aroC"
                     /locus_tag="PC466_002779"
     CDS             3744..4823
                     /gene="aroC"
                     /locus_tag="PC466_002779"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HDF2770145.1"
                     /translation="MSGIWGNNLKVSIFGESHGNAIGINIDGLPSGIELDLDKIDKEM
                     KRRAPGKNSISTSRNESDIPEILSGYFNGRTTGTPLCAIIRNSDTRSKDYGELKNLMR
                     PGHADFTGNVRYSGFNDYRGGGHFSGRITAPLVFCGAICKQILSQKGIEIGAHIKKIK
                     NIEDMSFDYVNISKQQLSNLQTLELPLLDLSKEEAMKNTIIDAKNQRDSVGGIIECAV
                     VGINVGLGNPFFDSVESTLSHLLFSVPAVKGVEFGLGFELADMYGSQSNDEMYYEGNQ
                     VKSKTNNNGGIIGGITTGMPIIFKVAIKPTPSISRQQNTVNIKDKKDDILYIKGRHDP
                     CIVQRAIPVIEAVTAIGIFDLMKGR"
     gene            4826..6022
                     /gene="pheA"
                     /locus_tag="PC466_002780"
     CDS             4826..6022
                     /gene="pheA"
                     /locus_tag="PC466_002780"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HDF2770146.1"
                     /translation="MEDLTRYRNEIDNIDKEIIQLFEKRMNTVLEIARHKMKNNTTIL
                     QKDREEKVLSRAIDNLDNKAYSQETVQFFNSIMEISRGLQKRLIDNDGEQKIEFSLDS
                     SNKKFDLSNVNKYKSLKDELNKKNILVGFPGKSGSFTEEALNKFFNKTISKKQFKEFE
                     DVFIALKNKEINYGIIPIENSSTGAISETYDLLRKYGFYIVGEECIKIDQNLIGIKDT
                     KLEDIKEIYSHPQGIGQCSEFLKQNSTWKLIPFNNTATSAELVRKLQDKTKAAIASKK
                     AASIYELEIISPCINDIANNYTRFVVISNQIHIEEESNKMSVVFSVEHEAGKLYKVLG
                     YFAENNINMTKIESRPMKNASWRYFFYIDFECSIYNSKVYDLLELIEHNTAYFKFMGV
                     YKNKTE"
     gene            6069..6878
                     /gene="aroE"
                     /locus_tag="PC466_002781"
     CDS             6069..6878
                     /gene="aroE"
                     /locus_tag="PC466_002781"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HDF2770147.1"
                     /translation="MNFFGLVGEKLSHSVSPQIHKRIFEILNIESAYKNFEIPKEDIS
                     KLDGAIKLLGIQGVNVTVPYKERIMKYLDFISPEAKRIGAVNTILLRENMLYGYNTDY
                     FGLDSMFKMANIDVQGKVAVILGTGGASKAALTYFIDSGIEKLYVSTRKKDDKKLLNS
                     KAILIDYEELKHIKGDIILNATPVGMYPNVGISPVSKSIIQNFDILIDLIYNPGETEF
                     LRIGNSMGKKTCDGLYMLVGQAIKSQEIWQDTKIDNSILDVIYNELKLEFL"
     gene            6890..7423
                     /locus_tag="PC466_002782"
     CDS             6890..7423
                     /locus_tag="PC466_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HDF2770148.1"
                     /translation="MINKTKEKLILIGMPGSGKTTIGKLLAKEYNCSFCDMDDYIIQI
                     SQKSIAELFSEGEDIFRNYETQACRELSISDKTVISTGGGVIKKDVNMEILKETGIII
                     FIDRPIQKILEDININSRPLLKNGKDRLYNLYNERINLYKKFSDIEILNDKSLNNAVY
                     NITNAVSENFKFDFKEK"
     gene            7444..8283
                     /locus_tag="PC466_002783"
     CDS             7444..8283
                     /locus_tag="PC466_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HDF2770149.1"
                     /translation="MNIVIVGLGVIGGSFAKALKKAGYENVFGVDVDLETLKKAEKAK
                     IIKKGCTTGKELFKKADLIILSIYPRLVVDFLNNNKNFFKKGTIITDTTGIKETLIND
                     VLQIIPDDIDFIFGHPMAGREKKGIDFASEQVFNGANYIITPTGRNNIKNLELVENLI
                     LEIGFKRVKKLTSQKHDEIIAFTSQLPHVMAVALINSDEEGRDTGKFIGDSYRDLTRI
                     ANMNEDLWSELFLGNRDNLLKVIENFESEVNLVKEAIFNNDKNKLIEYFKKSSIRREA
                     LEK"
     gene            8551..10032
                     /locus_tag="PC466_002784"
     CDS             8551..10032
                     /locus_tag="PC466_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDF2770150.1"
                     /translation="MKKNRLIIKNISIAFIVLFFFSVFTFFYIGNISRVLEYETNDIM
                     TVTITGWIILSFLFLCIIIYILYSKAKSQKTIEKVAYTDFVTGYSNWRKFELDVTNLL
                     KKTSQNNKYAMVIFDIDKFKAINDIYGHKKGNLILKDIADTLNELTNINETFARVSAD
                     NFNILLTYNKKEDIINIIKKIIANNELVNLSFGIYEIKDKDLSVSVYSDRASLAKSSI
                     KNNSDVNFAFFNDKLREKLLLEDKIEKEMEYALESGQFVMYLQPKYNIKLDKFCGSEA
                     LVRWQYTEKEVIYPGDFIPIFEKNGFIRKIDMYILEQACKEIRSLFDKGISPLPISVN
                     FSRVDFLKKDFIENIVNICDRYKIPYSLIEIEITESSMFGDTDTLFNVSRNLQDIGFI
                     VAMDDFGSGYSSVNMLKNIPLNVIKLDRGFFVDDKDVDKSQIVIKSIVSLIKQLGIRV
                     VAEGIETRSQIEMLKKANCDIVQGYYFSKPLPIKEFEKLVYKI"
     gene            10065..13502
                     /locus_tag="PC466_002785"
     CDS             10065..13502
                     /locus_tag="PC466_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing protein"
                     /protein_id="HDF2770151.1"
                     /translation="MIRAKSLKNVLSIVLIFLFTIISFSDFAFKTNVQEEENSKINLR
                     EISLQSSNAIKIKLDSSLSFIKSVANMVSYFNTIDNSKIVPLLANISKESDFQRISIV
                     SPDGISHTSDGKIINVSKYQYFKKAIKGESNISEVVKSPIDGKDTFVIATPIFNKNNK
                     IIGVLYGSYYNDKLAEFIDITSFNSEGYIDIFESSGQFVLKSSHTNKLIKSSSNIYDI
                     FKKASFDDGYSYKKIYEDTKNNKSGFTSYEYKGENRYATYTPIGVNDWYVISVIPQYT
                     VRRNIDKINQLAFSLIFKVFLLFIMLIIYIIYKNNKSQKDILKANKEISSITNSIPGG
                     VQKCTLGETCNINFLSDGFIELFGYTREEIKTLFNNDFYSLIHKDDVERIKKEISKQL
                     YKNKTIELEYRIITKNGNTVWVLDKGELITEPDGKEYFCCVTVDITRTKQLEQEMEQK
                     NLELEMISENILGGIIITEFNDDFTIKYTNSGYLSMIGYTREQLENELKYKACNLVFY
                     EDRKKALESIQHQLNTKGIAVYQHRIRRRDGNIIWVSIKGRLIIDDDGIEKGIWILND
                     ITDLKNAEQKLKINEERFRIALKQTSNTIFEYDIKTKSLLNTSKELDKYNIYKITKNV
                     PYSLVESGVIHKDFSDDFINMYENVINGAKKASCVVKMKLPDENYIWNKVTLTTIFDE
                     DGNPVRAIGIQEDISKQKEAEIRYNQEGKYHSAILSEAMITYEINVSKDTFIKGNESW
                     QKPFGIKPDNNYSEMVKTISNSIIHKDNKEVFLNTFLCKNLLSAYNKNITEIKLEYRR
                     MNQENKMIWVICTMHLIKDSITNDIKALAYVKDIDKQKNEEIKLKLKAERDTLTGLYN
                     KGTTENLINDFLNSDEASLGMHAFLIVDIDNFKSVNDNLGHVFGDKVLFEVSKHLKPI
                     FRKDDIVGRIGGDEFIVFLKNIQSFENTKKKAEKICDIFRNSYTENKKTYKISGTVGI
                     SFVPEHGTVFEELYKKADIALYYAKSKGKDKYALYNNCIYQNELENNISDNNIKLANK
                     CEKSKPVLKEILDSIDNYIYIVNPNTYELLFVNNKVSRLDLEIKLGETCYKSLLKSER
                     PCNNCPLNGLEENKHSKFKIETNTFGKNISIASWINCIDGEYNCLIECIDSSLYKNK"
     gene            13520..14266
                     /locus_tag="PC466_002786"
     CDS             13520..14266
                     /locus_tag="PC466_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HDF2770152.1"
                     /translation="MLNSITLILGIIFTIYYFYLKIVFGGISFSEIFLVVGIVLIIYQ
                     IFKKKIKEKKVFYRVLKIIISIFLIVFVVTESLIIFYPKNSLESKSDYLLILGASVKK
                     TTPSTTLKGRLDTALKYLKINDNCYVVVSGGKGSGEKITEAKAMKDYLIKNSIDKNRI
                     IEEDKSTNTYENFKYSKLKIEEHSQRKLSDLKVKIVTTDFHVLRSKILAYRNGYKNTS
                     FYASKSKLSFVPTYYTREFFALWKTIIFDR"
     gene            complement(14215..14535)
                     /locus_tag="PC466_002787"
     CDS             complement(14215..14535)
                     /locus_tag="PC466_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HDF2770153.1"
                     /translation="MEKIMNFLKENSTFYFATVEDNKPRVRSFGFIMDYEGKLYFGIV
                     KYKTSYKQLLVNPNVEISTTSKVGKWIRIKGIEKTRYEFISSLFIYYLSKMIVFHNAK
                     NSLV"
     gene            15326..>18509
                     /locus_tag="PC466_002788"
     CDS             15326..>18509
                     /locus_tag="PC466_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF11 domain-containing protein"
                     /protein_id="HDF2770154.1"
                     /translation="MATVSGQIVFDRNRSATIDSGDSGIANIPVVLQDIATGVRLVVL
                     TDASGNYVFTNVPNGNYRIVEAFGTTGGVPTPGNFATAIVGPVPIAEMPPISSVTNPP
                     IGSTNLDGTTPNTLLITVAGSDIINQNILNGPVIYTPIENILDSCVSVSNINLITDAD
                     NGTFGFFPPGTPSNTGPEIEPYPNVTPDFTYVVPDPTKFTPLDGEYTVQNIMTNAMSN
                     VIGAWWRIADHTTGNETGRMMVVNGFNPGAVFFKSTVQVTPNTNYLFSTWILNLFKVT
                     GYPPPQLGVRIFDQNNNILYQATLGAQIPVNTNAPEWKEVGTVINSQNNNQLTVEFFS
                     EGESAIGNDYAIDDVSLREIAVPTFTPIKTSNTETANVGDIITYTVTLDNTCDSPLTN
                     VFFRDLIPNGLEFIPGTVTVDGVSVPGVDPNTGFPLPDIGGGIGVEVTFDVVVESIPN
                     PNPTNNIATIDYSYTPVEGGIPNDFSVDSNPVPVEVISADVEVTKLSEPTIVNPGEEL
                     IYTIKVVNNGPFPSENVVLTDDVPASIINPEYSLDGGVTFQPWTGSLNIGTLEVGETR
                     VIIIRGIVNPSTVGIITNTAVVSSTTADPNLNNNTSTIETEVNLLADILVMKTAEPNS
                     AVPGTLLRYTIQVENLGPANAENVILNDDIPASIINPEYSLDGGASFQPWNGSLNIGT
                     LNSGISLTVLIQGTVSLNSSEYIVNTATVSSTTPDPDLSNNISTIITPVNPQAGISII
                     KVADEDVAVPGEEFVYTIEIFNEGPSNATNVVLTDDIPDVILNPEYSLDGGATFQPWN
                     GSLNIGTVAPGQLIRIIIKGLVSSTATGDITNTAEVSADVPEPVTDSSTVTTPIVPSA
                     DIEVIKTSNMDTAVPGETFSYTITVINLGPSAAQSIVLTDDIPDVILNPEYSLDGGVT
                     FQPWNGNLSIGTLDAGEIRSIIIRGTVSQTAVGTIINTATISSPTPDPNPDNNTSTDE
                     TDISPLADISVIKGNEPVAIPGGRFIYGIEIANAGPSFAENVTLTDNIPASILNPEYS
                     IDNGVTFQPWNGSLNIGTLDAGEIRNIIIRG"
BASE COUNT         7554 a         2028 c         3076 g         5851 t
ORIGIN      
        1 attatatttt ctttgttata attattaaac aagaagaata ataaattata aaaatggagg
       61 ataatactat gaaaggaata ttaaaagaac taacagcaaa actttatagc tttttttact
      121 ttatgttctg gggcttttat tttagcgctg gctatttctt ttacaaaaat atatgtactt
      181 cctttctggt gaggccttat tttagtgatt ttgagcataa gtaaatttta taaaaatgat
      241 tattttatat atttatataa gatttagtgc ttgatagatt attttagaga actcattagt
      301 gagttctctt ttttatttta aatataaaat tataatattg ggaggtagta aaaatgatag
      361 tagtattaaa aatgggagca gataaaaatg aagttaaaaa attaattgag gctattggga
      421 gagaaggagt agaagttaat cccatagatg gaacagaatt aactgtttta ggtttagttg
      481 gagatactag taaaatagat gccaaaagaa tagaagcaaa taagatagtt gaaaaagtta
      541 tgcatgtagt agagcctttt aaaaaggcca atagaaaatt tcatccagaa ccttcaatca
      601 taaatgttaa tggaatggaa attggttcaa agaaaattgc tatgatagct gggccttgtt
      661 ctgttgaaac agaagaccaa atagtatcta tagctaaaga tgtgaaaaaa tcaggtgcag
      721 gatttttgag aggtggagca ttcaaaccaa gaacatcacc atacgctttc caaggattga
      781 aatatgatgg attggattta ttaaaaaaag caaaagaaaa aacagggctt cctatagtta
      841 cagaaataat gtcaacacaa gatatagata tatttgaaga aaatgtagat gtaattcaag
      901 ttggagctag aaacatgcag aactttgatt tattaaaaga attaggtaaa acaaataaaa
      961 caatactttt aaaaagagga ttatctgcta caattgaaga gtggctaatg tcagcagagt
     1021 atataatggc tggaggaaat gaaaatgtag ttctttgtga aagaggtata agaacttttg
     1081 aaacatatac tagaaatact ttggatttaa gtgcaatttt agctgtgaag aaacttagtc
     1141 atttaccagt tatagttgac ccaagtcatg cagcaggtaa atcatggatg gttgactctt
     1201 tatctaaggc agcaattgca gttggagcag atggtctaat aatagaagtt cataatgacc
     1261 cagcacatgc actttgtgat ggaaaacaat cgattaagcc aaatgaatat gatgaattga
     1321 taagtgaatt aaagactatc gcatcagcag ttggtagaga aatataatct ataaaaggat
     1381 ggttaaacgt ggaagaaaaa ctattagtaa atttaaaaga aaatagctac aatatattta
     1441 ttaaaaaaaa tatactaaag aatataggag aagaaataaa aaaaatatat tttggaaata
     1501 agatttttat tgtaactgat gaaaatatag caaaattata cttggataaa gtaaaaaata
     1561 atttaagtga atctggattt gaaattaaat ctttaatatt aaaatctggt gaagaaacaa
     1621 aatcatttaa tactcttcct aaaatatacg atagtttact tgactttaag ttaactagaa
     1681 aagatttgat tattacttta ggaggagggg taataggtga tttaggtgga tttgcagcag
     1741 caactttttt aagaggtata agttttattc aaattccaac atctttatta gcacaagttg
     1801 atagttctgt aggtggaaaa gttggagttg accttgagag aggcaaaaat ttagtgggaa
     1861 gcttttacca accaaaagct gtgtttatcg acccaaatgt attattatca cttccagaaa
     1921 aattctatag agatggaatg gcagaagtta taaaatatgg atgtataaaa gacaaaactt
     1981 ttttcaataa acttttaagt ttaaaaaata gagaagaagt aatgcaacat atagaataca
     2041 ttatacataa atgttgcttt attaaaaaaa ctgtagttga agctgatgaa aaagactttg
     2101 gagatagaat gcttctaaac tttggccata cattaggtca tgctattgag aaatactaca
     2161 attttacggg ttatacccat ggagaagctg ttgccatagg aatgtataag ataactttag
     2221 aaagtgaaaa gataggaatt acaaaaaaag gtacatcaga acttataaaa tcaattttaa
     2281 tgaattataa tttgccttat gagattgaat taagagataa taaatctata gtagatgcta
     2341 tatctcttga taaaaaaaat ctaggtgata cattaaaaat aatactttta aaagatattg
     2401 gagagagtat tatatataat actacttcta aattttttca ggaggtaaga taatgggaag
     2461 tctaaaaata tatccaagta aattatctgg agatgtaaaa ataccaccat caaaaagtat
     2521 ggcacatagg gcagttattt gttcatctct aagcaatgga aaaagtagaa tttctaatat
     2581 agatttttct gatgatataa tagctactat aagagcaatg acatcattag gagctattat
     2641 agaaaagaaa gaagatattt tagaaatttc gggaattttt tctaaagaag gtattttaaa
     2701 tagagagaat cagttgaatc aacctaaatt gacaatagat tgtaatgaat caggctctac
     2761 attaagattt ttagtaccta tatctttagc atttgatggt gtaaaaaggt ttataggtag
     2821 aggtaatctt ggaaaaagac cacttgatac ttattatgag atatttgaca gacagaatat
     2881 aaaatatagt tacaaagaaa atcagttaga tttgattata tcaggtaagc ttaaaccaga
     2941 tgaatttaga gtaaaaggaa atataagttc tcagtttatc acaggtctat tgtttatatt
     3001 gcctacacta gagagtgatt caaagataat aattactact gagctagaat ctaaaggata
     3061 tttagattta actctttcaa cgataaaaga ttttggggta gaaattataa acaataacta
     3121 taaagaattt attataaaag gaaatcaaac gtataaagcg agagattata aagtagaagg
     3181 agattattct caaggagcat tttatttatc agcagatgct ataggagaag atattagcat
     3241 attagacctt aaagaagatt ctcttcaagg ggatagtgaa gtagttgaaa ttttatctag
     3301 gatgggaatg gaaatattaa gagaaggcaa caaaataaaa ggaataacaa atggtttaaa
     3361 tagtactttg atagatgcat ctcaatgccc agatataata cctgtattat ctgtagtagc
     3421 atccttaagt atagggagga ctacaataat taatgctggt aggcttagaa ttaaagaatg
     3481 tgatagactt catgcaataa atgttgagtt aagtaaactt ggagcaaata tagaggagaa
     3541 agaggatagt ttgataatcg aaggagtaag caagttaaat ggtggagtag aggtgtggag
     3601 tcacaaagac catagaattg ctatgacact tgcaattgct tcttgtagat gtgataaacc
     3661 aataatatta aaagattttg agtgtgtatc aaaatcttat ccacattttt ttaaagattt
     3721 taagatgtta ggaggtcgaa ttgatgagtg gaatatgggg aaataattta aaagtatcaa
     3781 tttttggaga atctcatgga aatgctatag gtataaatat agatggtctt ccttcgggga
     3841 ttgaacttga ccttgataag attgataaag aaatgaagag aagagcacct ggaaaaaatt
     3901 ctatatctac ttcaagaaat gaaagtgata taccagaaat tctaagtgga tattttaatg
     3961 gaagaactac aggaacgcca ttatgtgcaa tcataagaaa tagtgatact cgttcaaaag
     4021 attatggaga gcttaaaaat ttaatgagac caggacatgc agatttcaca ggtaatgtga
     4081 gatattctgg atttaatgac tatagagggg gaggtcattt ttcaggtagg ataacagctc
     4141 cattagtatt ttgtggggct atatgtaaac aaattttatc acaaaaagga atagagatag
     4201 gagcacacat aaaaaaaatt aaaaatatag aagatatgag ttttgattat gtaaatattt
     4261 caaaacaaca gttatcaaat ttgcaaactt tggaactacc tttacttgat ttatcaaagg
     4321 aagaagccat gaaaaatacg attatagatg caaaaaatca aagagattca gttggtggta
     4381 taattgagtg tgcagtagta ggtattaatg tagggcttgg aaatccattt tttgactctg
     4441 ttgaatctac tttatcacat ttattgtttt ctgttcctgc cgtaaaaggt gtagagtttg
     4501 gtttaggttt tgaacttgca gatatgtatg gctctcaaag taatgatgaa atgtattatg
     4561 aaggaaatca agttaagagc aaaacaaata acaatggagg gattatagga gggattacta
     4621 ctggaatgcc aataattttc aaagtggcaa ttaagccaac tccttcaatt agcagacaac
     4681 aaaacacagt taatataaaa gataaaaagg acgatatttt atatattaaa ggcagacatg
     4741 acccttgtat agttcaaagg gctatacctg taatagaagc agtaacagcc attggaattt
     4801 ttgatttgat gaaaggacga taataatgga ggatttaacg agatatagaa atgagattga
     4861 caatatagat aaagagatta ttcaattatt tgaaaagaga atgaatacag ttcttgaaat
     4921 tgccagacat aaaatgaaaa ataacactac tatacttcaa aaagatagag aagaaaaagt
     4981 actaagtaga gccatagata atttagataa taaagcatac tcacaagaaa cggtacagtt
     5041 ttttaattct ataatggaaa ttagtagagg attacaaaaa agattgatag ataatgatgg
     5101 tgagcagaaa atcgagttta gtttagattc atcaaataag aaatttgatt tgtcaaatgt
     5161 aaataaatat aagtctttaa aagatgaatt aaataaaaaa aatatcctag taggatttcc
     5221 aggaaaatca ggttcattta cagaagaagc actaaataaa ttcttcaaca aaacaatatc
     5281 aaaaaaacaa tttaaagaat ttgaagatgt tttcatagca cttaaaaata aagaaataaa
     5341 ctatggaata atccccatag aaaattcatc tacaggagct atctctgaaa cttatgacct
     5401 tttgagaaag tacggttttt atatagttgg agaagaatgt ataaaaatag accaaaattt
     5461 aatagggata aaagacacaa aacttgaaga tataaaagaa atatattctc atccacaagg
     5521 tataggacaa tgtagtgaat ttttaaaaca aaatagtaca tggaaattga taccatttaa
     5581 taacacagca acaagtgcag aacttgtaag aaaacttcaa gataaaacaa aagcagcaat
     5641 tgcaagcaaa aaagctgcaa gtatttatga attagaaata ataagtcctt gtataaatga
     5701 tattgcaaac aactatacaa gatttgtagt aatcagtaat caaatacaca ttgaagaaga
     5761 atcaaacaaa atgagtgtag tattttctgt tgaacatgaa gcaggaaaac tttataaagt
     5821 acttggatac tttgctgaaa ataatataaa tatgacaaaa atagagtcaa gacctatgaa
     5881 aaatgcctca tggagatatt tcttttatat agattttgag tgttctatat acaattctaa
     5941 agtgtacgac ttattagaat tgatagaaca taatacagca tattttaaat ttatgggagt
     6001 atataaaaat aaaactgaat agataatata aatttttatt taatttataa ttattaggag
     6061 gtgtaagtat gaattttttc ggtctagtag gtgaaaaact ctctcacagt gtttcacctc
     6121 aaatccacaa gagaatattc gagatattga atattgaaag tgcttataaa aactttgaaa
     6181 ttccaaaaga agatatatct aagctagacg gtgctataaa attattagga atacaaggag
     6241 taaatgttac tgtaccatat aaggagcgta ttatgaaata tcttgatttt atatcaccag
     6301 aggcaaaacg tataggagca gttaatacaa ttttactcag agaaaatatg ttatatggtt
     6361 acaatacaga ttactttggt cttgatagta tgtttaaaat ggctaatatt gatgttcaag
     6421 gaaaagtagc agttatatta ggaactggag gtgcttctaa agctgctctt acatatttta
     6481 ttgattctgg tatagaaaag ctttatgttt caactagaaa aaaggatgat aaaaaattat
     6541 taaatagtaa agctatatta atagattatg aagaacttaa acatataaaa ggagatataa
     6601 tattaaatgc tacaccagta ggtatgtacc ctaatgtagg aatttcacca gtgtcaaaat
     6661 ctattataca aaattttgat atattaatag atttaattta caatcctgga gaaacagagt
     6721 ttttaagaat tggtaatagt atgggtaaaa aaacttgtga tggattatat atgctggtag
     6781 ggcaagcaat aaaatctcag gaaatttggc aagatactaa aatagataat agtattttag
     6841 atgttatata taatgaacta aaattagaat ttttgtaagg gagattgtca tgataaataa
     6901 aacaaaagaa aaattgatat taataggtat gccaggtagt ggaaaaacta caattggtaa
     6961 acttttggcc aaagaatata attgtagttt ctgtgatatg gatgattata taattcaaat
     7021 atctcaaaaa agtatagcag agttgttttc agaaggagaa gatatcttta ggaactatga
     7081 gactcaagca tgtagagaac tttctataag tgataaaaca gtgatatcta caggtggagg
     7141 tgtaataaaa aaggatgtta atatggaaat actaaaagaa acaggtataa taatttttat
     7201 tgatagacct atacaaaaga ttttggaaga tataaatatt aattcaagac cattattaaa
     7261 aaacggaaaa gatagattgt ataatcttta taatgagaga ataaatcttt ataaaaaatt
     7321 ttcagatata gagattttaa atgataaatc attaaataat gctgtatata atattacaaa
     7381 tgcagtcagt gaaaatttta aatttgactt taaagaaaaa taatctaggg ggaaataaaa
     7441 ataatgaata ttgttattgt aggactagga gttataggag gctcttttgc taaagcatta
     7501 aaaaaagctg gatatgaaaa tgtatttgga gtagatgtag atttagaaac tttaaaaaaa
     7561 gcagaaaaag caaaaatcat aaaaaaagga tgtactacag gtaaagagtt atttaaaaaa
     7621 gctgatttaa ttatactatc tatatatcct agattagttg tagattttct aaataataat
     7681 aaaaactttt ttaaaaaagg gactataatt actgatacta caggaataaa agaaacactt
     7741 atcaatgatg tgttgcaaat tattccagat gatatagatt ttatatttgg acatccaatg
     7801 gcaggtaggg aaaaaaaggg tattgatttt gcaagtgaac aagtttttaa tggcgcaaat
     7861 tatataatta ctccaactgg cagaaacaac ataaaaaatt tagagttagt tgaaaattta
     7921 attttagaga ttggatttaa aagagtaaaa aagttaactt cacaaaaaca tgatgagatt
     7981 atagctttta cttctcagtt acctcatgtt atggcagttg ctcttataaa tagtgatgaa
     8041 gaaggtagag atacaggtaa atttattgga gatagttata gagatttaac tagaattgca
     8101 aatatgaatg aagacttatg gagtgaactt tttttaggaa atagagataa tttactaaaa
     8161 gttatagaaa actttgaatc agaagtaaat ttagtaaaag aagctatatt taacaatgat
     8221 aaaaataaat tgatagagta ttttaaaaaa tcatcaataa gaagagaagc tttagaaaaa
     8281 taaatattaa tatttaagct atatatagat gggtataaat gtaagcgata gtgtatttaa
     8341 ttgtattaat aaatatggat tcaatataat taaatatgct attgatatat ttgtaccctt
     8401 aactattgtt atcttttaaa tgataatgat atttatttaa atgctcttta ttaacaattt
     8461 ataaaactta attgtaaaaa atacttatta atagtaaaat aaagtgaatc aattatatta
     8521 taattgctaa agagagtgag gtgtagctat ttgaaaaaaa atagattaat aataaagaat
     8581 atatcaatag catttatagt actattcttt tttagtgtat ttacattctt ttatataggt
     8641 aatattagta gagtattaga atatgaaaca aatgacataa tgacagttac aattactgga
     8701 tggattatac tttcattttt atttttatgt attataattt acatattata ttcaaaagca
     8761 aagagtcaaa aaactataga aaaagtagca tatacggatt ttgtaacagg ttattccaac
     8821 tggagaaagt ttgaattaga tgttacaaat ttattaaaga aaacatcaca aaataataaa
     8881 tatgcaatgg tcatattcga tattgataaa tttaaagcaa ttaatgatat atatggacat
     8941 aaaaagggca atttaatatt aaaagatatt gcagatactt taaatgaatt gactaatatc
     9001 aatgaaactt ttgctcgtgt aagtgctgat aattttaata tattattaac atataacaaa
     9061 aaagaggata taataaatat tattaaaaaa attatagcaa ataatgaact tgtaaactta
     9121 tcttttggaa tttatgaaat caaagataag gatttatctg taagtgtata tagtgataga
     9181 gcttcacttg caaaatcatc aataaaaaat aatagtgatg taaattttgc attttttaat
     9241 gataaattaa gagagaaatt attacttgaa gataagatag aaaaagaaat ggaatatgct
     9301 cttgaaagtg ggcaattcgt aatgtattta caaccaaaat ataatattaa attagataaa
     9361 ttttgtggaa gtgaagccct agtcagatgg caatatacag aaaaagaagt catatatcca
     9421 ggtgatttta ttcctatatt tgaaaaaaat ggatttatta gaaaaattga tatgtacata
     9481 ttagaacaag cttgtaaaga aatccggtct ttatttgata aaggaatttc acctttacct
     9541 atatctgtaa acttctcaag agttgatttt ttaaaaaaag attttattga aaacatagta
     9601 aatatatgtg atagatataa aataccatat agtttaatag aaattgaaat tactgaatct
     9661 agtatgtttg gagatactga tactctattt aatgttagta gaaacctaca ggatattggt
     9721 tttatagttg caatggatga ttttggctcg ggatattctt ctgtaaatat gcttaaaaat
     9781 ataccattaa atgtaataaa attagataga ggattttttg ttgatgataa agatgttgat
     9841 aagagtcaaa ttgttataaa aagcatagtt tctctcatta agcaattagg aataagggtt
     9901 gttgctgaag gaattgaaac aagaagtcaa atagaaatgt taaaaaaagc aaattgtgat
     9961 attgttcaag gatattattt ttcaaaacca ttaccaatta aagaatttga aaaattagtc
    10021 tataaaatat agtcagcgag tcttaaatgg gaggtggtga ttaagtgata agagcaaaat
    10081 cgttaaaaaa tgtactgagt attgttttaa tatttttatt tacaataatt tctttttctg
    10141 attttgcatt taaaactaat gtccaggaag aagaaaatag taaaattaat ttaagggaaa
    10201 tatccctaca aagttccaat gctataaaaa taaaattaga tagttctcta tcctttatta
    10261 aaagtgtggc aaatatggtt tcttatttta atactataga taactcaaaa atagttccat
    10321 tattagctaa catatcaaaa gaatctgact ttcaaagaat ctctattgta tctcctgatg
    10381 gaataagtca taccagcgat ggcaaaatta tcaatgtgtc aaaatatcag tattttaaga
    10441 aagctattaa aggagaaagc aatatatctg aagttgtgaa atctccaatt gatggaaaag
    10501 atacttttgt tatagctact cctatattta ataagaataa caaaataatt ggtgttttat
    10561 acggttctta ctacaatgat aaattagctg aatttataga tataacaagt tttaatagtg
    10621 aagggtacat agatatattt gaatctagtg gtcaatttgt tttaaaatct tcacatacaa
    10681 acaaactgat taagtcaagt agtaacatat atgatatatt taaaaaagct tcttttgatg
    10741 atggttatag ctataaaaaa atatatgaag atacaaaaaa taacaagagt ggctttacct
    10801 catatgaata caaaggagaa aatcgttatg ctacttatac acccattggt gtaaatgact
    10861 ggtatgtaat ttctgtgata ccacaatata ctgtaagaag aaacattgat aaaataaatc
    10921 aattagcatt ttctcttatt ttcaaagtat tcttattgtt tattatgctt ataatatata
    10981 ttatttataa aaacaataaa tctcagaaag atatactaaa agctaacaaa gaaatctcat
    11041 ctattacaaa tagcattcct ggaggagtac aaaagtgtac cctgggtgaa acatgcaata
    11101 ttaatttttt aagtgatgga tttatagagt tgtttggtta tacaagagaa gaaataaaaa
    11161 cattgtttaa taatgatttt tatagtttaa tacataaaga tgatgttgaa agaataaaaa
    11221 aagaaatttc taaacaactt tacaaaaata aaactattga attagaatat aggattataa
    11281 caaaaaatgg taatacagta tgggttttag ataaaggaga acttataaca gaacctgatg
    11341 gaaaagaata tttttgttgt gtaactgtag atattactag aacaaaacaa ttagaacaag
    11401 agatggaaca aaaaaatcta gaacttgaaa tgatatcaga aaatatttta ggtggtataa
    11461 ttataacaga atttaatgat gattttacta taaaatacac taactctggt tatctttcaa
    11521 tgattggata tacacgtgaa caattagaaa atgaacttaa atacaaagct tgtaatcttg
    11581 ttttttatga agatagaaag aaggctcttg aaagtataca acatcaatta aacacaaaag
    11641 gaatagctgt atatcaacat agaataagaa gaagagatgg taatattatc tgggtttcta
    11701 taaaaggaag gcttattatt gatgatgatg gtattgaaaa aggtatttgg attctaaatg
    11761 acataacaga tttaaaaaat gcagaacaaa aacttaaaat aaatgaagaa agatttagaa
    11821 ttgcattaaa gcaaacatca aatactatat ttgagtatga tataaaaaca aagtcacttt
    11881 taaatactag taaagagctt gataaatata atatttataa aattactaaa aacgttccat
    11941 attctctagt agaatcagga gttattcata aagattttag tgatgatttt ataaacatgt
    12001 atgaaaatgt aataaatgga gcaaaaaaag caagttgtgt agttaagatg aaacttccag
    12061 atgaaaatta tatatggaat aaagttacct tgactactat ttttgatgaa gatggtaatc
    12121 ctgtaagagc aattggtata caggaagata taagcaaaca aaaggaagca gagataagat
    12181 ataatcaaga aggtaagtat cattcagcta tattgtcgga agcaatgata acctatgaaa
    12241 taaatgtatc aaaagatact tttatcaaag gaaatgaaag ttggcaaaaa ccatttggaa
    12301 ttaagcctga caataattat tctgaaatgg taaaaactat atcaaacagt attattcaca
    12361 aagacaataa agaggtgttt ttaaatacat ttttgtgtaa aaatttatta tctgcatata
    12421 acaaaaatat aactgaaata aaattagaat atcgaagaat gaatcaagaa aataaaatga
    12481 tttgggtcat ttgcacaatg cacttaataa aagattctat tacgaatgat ataaaagcac
    12541 ttgcttatgt taaagatatt gacaagcaaa aaaatgaaga aattaaatta aaattaaaag
    12601 ctgaaagaga tactcttaca ggattatata ataaaggtac tacagaaaat ttgattaatg
    12661 atttcttgaa ctctgacgaa gcaagcttag gaatgcatgc atttttaatt gttgatatag
    12721 ataattttaa atctgtaaat gataatttag gacatgtatt tggagataaa gtattatttg
    12781 aagtttctaa acacctaaaa cctatattta gaaaagatga tatagtaggt cgaattggtg
    12841 gagatgaatt tatagtattc ttaaaaaata ttcagtcttt tgagaatacc aaaaagaaag
    12901 cagaaaaaat atgcgatata tttagaaatt cttatacgga aaataaaaag acatataaaa
    12961 tatctggaac agttggaatt tcatttgtac cagaacatgg aactgtattt gaagaacttt
    13021 ataaaaaagc agacatagca ctttattatg caaagagcaa aggaaaagat aagtatgcac
    13081 tttataataa ttgtatctac caaaatgaac ttgaaaataa tataagtgat aataatataa
    13141 aattagcaaa taaatgtgag aaatccaaac cagtacttaa agaaattctt gattctattg
    13201 ataattatat ttatatagtg aatccaaata cttatgaact tctttttgtc aataataagg
    13261 tgtctcgttt ggatttagag ataaaattag gagaaacctg ttataaatca ctattaaaat
    13321 ctgagagacc atgtaataat tgccctctta acggattaga agaaaataag cattcaaaat
    13381 tcaaaataga gacaaataca tttggtaaaa atatcagtat agcaagttgg attaattgca
    13441 tagatggaga atacaactgt cttatagagt gtatagattc ttctttatac aaaaataaat
    13501 aaaaaaggac tatgaagata tgttaaatag tataactttg atacttggta taatatttac
    13561 aatttactat ttttatctca aaatagtttt tggaggaatt tcatttagtg agattttctt
    13621 agttgtagga attgtactaa ttatctatca aatatttaag aaaaaaatta aagaaaagaa
    13681 ggttttttat agggtgttaa aaataataat cagcattttt ttaatagtat ttgtagttac
    13741 tgagagttta attatttttt atcctaaaaa tagtttagaa tcaaaaagtg attatctctt
    13801 aattttagga gcttctgtaa aaaagactac accaagtaca accctgaagg gtaggttaga
    13861 cactgcattg aaatacctaa aaattaatga taattgttat gtggtagtat ctggtggtaa
    13921 aggaagtgga gaaaaaataa ctgaggcaaa agctatgaaa gattatctta taaaaaatag
    13981 tatagataaa aataggataa tagaagagga taaatccacg aatacttatg agaattttaa
    14041 atattcaaaa ttgaagatag aagaacatag tcaaagaaaa ctaagtgatt taaaagtaaa
    14101 aatagtaaca acagattttc atgttctcag aagtaaaata ttagcatata gaaatggata
    14161 taaaaatacg tctttttatg ctagtaaatc aaaactttca tttgtaccaa cttactatac
    14221 aagagaattt tttgcattat ggaaaacaat catttttgat agataataaa taaaaagact
    14281 agatataaac tcatatctag tcttttctat tcccttaatt ctaatccatt ttccaacttt
    14341 acttgttgta gaaatttcaa cattgggatt tacaagtaat tgcttataag aagttttata
    14401 ttttacgatt ccaaaatata attttccttc ataatccatt ataaatccga atgatcttac
    14461 tcttggttta ttatcttcaa ctgtagcaaa atagaatgtt gagttttctt ttaaaaaatt
    14521 cattattttt tccatgatta aatcctcttt gtatcttata ctaatataat gaatataaat
    14581 aaaatattta taatactaat ataaattgat ataaaaacaa ttacaatatt atattgatta
    14641 ttcaaaatta tatataaaat tcagaaaaac atttcagttt acataataaa aataaagtaa
    14701 actaaaatta ttgattttag attaaagtgc cagattaagt atttaagtag attttaagct
    14761 tgatttgatt agaaaggtac aaactatcac cgaaaaaaat taaacccatt taaaaagcaa
    14821 tataaaagct tgttattttc gagaaaaata gaccctctaa actcaattag ataaaaataa
    14881 aatacaaaaa attatatctc tgaatatctc aagtaattaa gtttaaattt tacgatattt
    14941 tgtttgatga tttataatat aaaagcatat tcttaatctt ctcaaattaa aaagagtaaa
    15001 aaataacaaa aaaatcactg acatttcact gacaaattgt aattttgtta ttataaatac
    15061 attgaaaata cttgattatt gaaaaatggc ataaaataat accttttatg ccatttacta
    15121 ttgtttgata gtttttaact tatgacataa gatatttttt aacatataca ataaaatata
    15181 aaaaaattga tattgcaaat aaaaaaaata catattagat gttatagaaa aaaagcgcac
    15241 ttataggctt aaaatgtcac ataaaagagt ttcaaagaat aatatattat gaacacaaat
    15301 tttgtaatca caaaggagtg ataatatggc aacagtatca ggacaaatag tttttgatag
    15361 aaatagaagt gctaccattg attctgggga ctcaggaata gccaatatac cagttgtatt
    15421 acaagatata gcaactggag ttagacttgt ggttctcaca gatgcatcag gaaattatgt
    15481 ttttactaat gttccaaatg gtaactatag aattgtagaa gcttttggaa ctacaggagg
    15541 agtaccaaca ccagggaatt ttgcaacagc gatagtaggt ccagttccaa ttgcagaaat
    15601 gccacctatt agttctgtga caaatcctcc tattggttca acaaacttag atggtacaac
    15661 acctaacaca ctattaataa cagtagcagg ttcagatata ataaatcaaa atatattaaa
    15721 tgggcctgtg atttatacac ctatagagaa tatattggat tcttgcgtgt ctgtatctaa
    15781 tataaacctt attacagatg cagataacgg aacattcggt ttttttccac caggtacacc
    15841 aagtaataca ggacctgaaa tagaacctta cccaaatgtg acgccagatt ttacgtatgt
    15901 tgtaccagac ccaactaagt ttacaccttt agatggagaa tatacagtac aaaatattat
    15961 gacaaatgca atgagtaatg ttataggagc ttggtggcgt attgctgacc atactacagg
    16021 aaatgaaaca ggaagaatga tggtggtaaa tggttttaat cctggagctg tattttttaa
    16081 atcaacagta caagttacac ctaacactaa ttatttattt agcacttgga ttttaaacct
    16141 ttttaaggta acaggatatc caccaccaca gctaggtgta agaatatttg accaaaataa
    16201 taatatacta tatcaagcaa cattaggagc tcaaattcca gttaatacaa acgcaccaga
    16261 atggaaagaa gtaggtactg tgattaattc tcaaaataat aatcaactta cagtagaatt
    16321 ttttagtgaa ggagaaagcg ccattggaaa tgactatgct atagatgatg tttctttaag
    16381 agaaatagct gttccaacct ttactccaat aaaaacaagt aacacagaaa ctgctaatgt
    16441 aggtgatata atcacatata cagttacatt agataatact tgtgatagcc ctttaactaa
    16501 tgtatttttt agggatttaa ttccaaatgg tttagagttt atacctggaa ctgtaacggt
    16561 tgatggagta tctgtaccag gagtagaccc taatacaggt tttccacttc cagatattgg
    16621 aggaggaata ggggttgaag taacttttga tgttgtggtt gaaagtattc ctaacccaaa
    16681 tcctactaat aatatagcta ctatagatta ctcctataca cctgtagaag gcggtatacc
    16741 aaatgatttt tcagtagatt ctaatccagt tcctgttgaa gtaatctcag cagatgttga
    16801 agttacaaaa ttatctgaac ctactatagt gaatccagga gaggaattaa tatacactat
    16861 aaaagtagta aataatggac cattcccatc tgagaatgtg gttttaacag atgatgtacc
    16921 agcttctatt ataaatccag agtattcatt agatggagga gtaacttttc aaccatggac
    16981 tggaagttta aatataggga cattagaagt aggagagaca agagttatta taattagggg
    17041 tattgtaaat ccatcaacag taggaattat aacaaataca gctgtagtat cttcaactac
    17101 agcagaccca aaccttaata ataatacatc tacaatagag acagaagtga atttattagc
    17161 agatatttta gtaatgaaaa cagcagaacc taattcagct gttccaggta ctttattgag
    17221 atatactatt caagtagaaa acttaggacc agcaaatgct gaaaatgtaa tattaaatga
    17281 tgatattcca gcctctatta taaatccaga atattcattg gatggaggag caagttttca
    17341 accatggaat ggaagtctta atataggaac tttaaactct ggaatttcat taacagtttt
    17401 aattcaagga acagttagtt taaattcttc agaatatata gtaaatacag caacagtttc
    17461 ttcaactaca cctgacccag atttaagcaa caatatatct accattatta caccagttaa
    17521 cccacaagca ggtatttcta ttataaaagt agctgacgag gatgtagctg ttccaggaga
    17581 agaatttgta tatacaattg aaatttttaa tgaaggacca tctaatgcta cgaatgtagt
    17641 tttaacagat gatataccag atgttatttt aaatccagaa tattcattgg atggaggagc
    17701 aactttccaa ccatggaatg gaagtcttaa tataggtaca gttgcaccag ggcaattaat
    17761 aagaattatc ataaagggat tagtaagttc aactgctaca ggagatatta ctaatacagc
    17821 agaagtaagt gcagatgtac cagaaccagt tacggattca tcaacagtga caactcctat
    17881 agttccatca gcagatatag aagtaataaa aactagcaat atggatacag cagttccagg
    17941 agaaactttt agttatacta taacagttat aaatttagga ccatctgctg cacaaagtat
    18001 cgttttgaca gatgatatac cagatgttat tttaaatcca gagtattcat tggatggagg
    18061 agtaactttc caaccatgga atggaaatct tagtataggc actttggatg ctggagaaat
    18121 aagaagtatt ataataagag gaacagtgag ccagacagca gtaggtacaa ttataaatac
    18181 agcaacaata agttcaccta cacctgaccc aaatccagat aataatactt caacagatga
    18241 aacagatata agtccattag cagatatttc tgtgataaaa ggcaacgaac cagttgctat
    18301 accaggggga agatttattt atggaattga aattgcaaat gcaggaccat cttttgcaga
    18361 gaacgtaact ttaacagata atataccagc ttctatttta aatccagagt actcaataga
    18421 taatggagtg actttccaac catggaatgg aagccttaat ataggtactt tagatgctgg
    18481 agagataaga aatatcataa taaggggaa
//
LOCUS       DAMJYN010000073        18377 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.076, whole genome shotgun sequence.
ACCESSION   DAMJYN010000073 DAMJYN010000000
VERSION     DAMJYN010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18377)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18377)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18377
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.076"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            <1..846
                     /locus_tag="PC466_002789"
     CDS             <1..846
                     /locus_tag="PC466_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDF2770155.1"
                     /translation="YINFRNSYINLYNCIENSGEIDSYLIDGQSFEENLIKDIIENLK
                     IKNNSDIETYKQSLKELDDYIAKWVHEIKIPISSLSIITDRLSSIEDSLDIKNQVAKI
                     NFLVNSILYSSRSNTMFEDVFINKFNLEKLVKMSIKNNSFLLIKNNVEVSLNELENDV
                     YTDSKCMSYVLDQIINNAIKYSKEVGKIEFNSKKLENGVVLSIKDFGIGINEEDISRV
                     FDKGFTGKNGRNQLYKSTGMGMYFVKKMIDSLGHEIEVCSKIGSYTIFNIYFYDISDY
                     LSLDS"
     gene            1276..2436
                     /locus_tag="PC466_002790"
     CDS             1276..2436
                     /locus_tag="PC466_002790"
                     /EC_number="2.7.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anhydro-N-acetylmuramic acid kinase"
                     /protein_id="HDF2770156.1"
                     /translation="MITMYSVGLMSGTSLDGVDAVLAEISGNGRNTKVKQIEFITLEI
                     PKDIKDEIRKCCIEEESSVDLICSLNFKLGYLFSKAVKSVCHKANFHIANLDFIASHG
                     QTIFHIPRSYNNFVSSTLQIGEPAIIAYETNTKVISNFRVMDIAAGGEGAPLVPYSEF
                     LLYSDKNKNLALQNIGGIGNITIIPKSCNIDDVFAFDTGPGNMIIDGVCQRLFNRKYD
                     KNGYFASKGKINEEMLKDLMSHKYLSQAPPKSTGREVFGQVYLDNMLNKYKHVDKYDL
                     IATVTMFTAKAIYYNYKNFILPKVNVDTLLIGGGGVHNLTLIGYIKELLLEVEVLTQD
                     EYGYSSDAKEALAFVILGNETLNNSFSNVISATGAKNKVILGNITPKPFGGK"
     gene            2438..2827
                     /locus_tag="PC466_002791"
     CDS             2438..2827
                     /locus_tag="PC466_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770157.1"
                     /translation="MSNNKKKKRKKNNNYKNAKSNKNTKKEMEKNQRTDYNIPTISFK
                     SGLILIVSSLVSTVVFPLLLSIFGIDNRFGVVIGNSLITSFAVAYTRYFVETKRGFSL
                     GFFRLYILFVLSFAIIGYFWIYKGIHI"
     gene            3088..3396
                     /locus_tag="PC466_002792"
     CDS             3088..3396
                     /locus_tag="PC466_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2770158.1"
                     /translation="MRVLFVCSSGMSSAIAVNALQKEGAKNGIDIDVLAVGTQEFENE
                     VKNGWDIAMVAPQVRHRFDYLKAFADEASVPCALIQAQAYSPLGGPKLLKQVQELLSK
                     "
     gene            3485..4831
                     /locus_tag="PC466_002793"
     CDS             3485..4831
                     /locus_tag="PC466_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF2770159.1"
                     /translation="MLDKFTEFLDSKLSTSMARLAEQRHLRAVRDGIVASLPLIIVGS
                     FFLILAFPPLPDSWGVTQYLKENAVTILLPYRMTFFIISVYSTFGIGYSLAKSYKLDG
                     LTGGLLATATFLLTIVPTAIEGLTPDLLKIVEKSPELLAWYNSIPQGWQMPMANLGGG
                     SMFVAIVTSIIGVEIYRFTDKSKFKITMPEAVPASVTRSFEALTPAALIIILMAIVTY
                     FLGFDWHGFIAKLVTPLVSATDTLPSVIILIFLITFFWSFGIHGVSIIGSLARPLWIQ
                     LLDANTASYAAGQAVPGIAAEPFFQWFIWIGGSGATIGLALLLAFRAKSAYGKSLGKA
                     TVIPAIFNINEPIIFGAPIVLNPILIIPFVVAPIVMATVSWFAMSANLVSRVVVTAPW
                     TLPGPVGAYLATGGDWRASVLNLLCIAISIIIYYPFVKMYDKRLLHEEKVEEQEAY"
     gene            5064..6161
                     /locus_tag="PC466_002794"
     CDS             5064..6161
                     /locus_tag="PC466_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HDF2770160.1"
                     /translation="MGRLGISIYPEKTTSKEIYDYIDKAAENGFTRIFSCLLSVKDTK
                     ENIIKKFKSINEYAKFKGFEVILDVNPRVFGELEISYKDLTFFKKTKADGIRLDMGFT
                     GSEKALMTFNPQNLKIEINMSNNTNYIDTIMDYQPNKENLTGCHNFYPHRYSGLNLEH
                     FIKCTERFNKYGLRTAVFVTSQNETTFGPWPVTDGLPTIEMHRNLPIDIQVKHIIAMN
                     NINDIIISNCYPTYEELKVLGSMRKDMVTFDVAIEENIREVEKKILFEEIHFNRGDIS
                     DSLIRSTQSRVKYKGYKFELFNTPKIIKRGDIVIESSEYGHYAGELQIALTDMKNSGK
                     SNVVGYIRKEELFILDYIKPWQKFDFKPSTK"
     gene            6260..7174
                     /gene="murQ"
                     /locus_tag="PC466_002795"
     CDS             6260..7174
                     /gene="murQ"
                     /locus_tag="PC466_002795"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HDF2770161.1"
                     /translation="MLIKTLENLVTEGRNKNTLQIDKEDTLGIIELINNEDKTVAYAV
                     EEQKESIAKAVNIIVDRMKQGGRLFYIGAGTSGRIGILDATECPPTYGVDFELVQAII
                     AGGNQAIFKAIEGAEDDKELGKQDIIDRGVTSKDVICGIAASGRTPYVIGAMEYAKEL
                     GCAVLSITMNPNSEMSKKADLPINIIVGAEVIMGSTRMKSGTAQKMVCNMLTTASMVK
                     MGKVYSNLMVDVKTSNEKLVERAKRIIMIATNVKYDVAEKFLEEADNRVKLAIFMIKS
                     GLDKDSAKSILDRQEGYISEALKSIEKL"
     gene            7284..8204
                     /locus_tag="PC466_002796"
     CDS             7284..8204
                     /locus_tag="PC466_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA reductase"
                     /protein_id="HDF2770162.1"
                     /translation="MYFLGVDGGGTKTTFTLVDEELNIVGTITKGTCHYNQIGFDNLT
                     KLLITGLEEVCKDAKINVEEITYAFVGLAGYGKIKEVLYALEVATKNAYSHINYTLGN
                     DVEIALAGSLNGEKGINIIAGTGSIAQALDKDGNLHRCGGWGYVLGDEGSAYYIGMAT
                     LKMFTMQSDGRCSKTKLYDLIKRHLNIENDYDIIKYVNDGIQGDRIEIAKFATICLKA
                     VIEGDNTASKIFDDAAYELSRLIIGLEHHFEQGTKIKVSYSGGVFKSGDLILEPLKKY
                     LNKTRFGIVRPVLTPDLGACLLAKKKYYSK"
     gene            8221..9072
                     /locus_tag="PC466_002797"
     CDS             8221..9072
                     /locus_tag="PC466_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDF2770163.1"
                     /translation="MSCILKLKQIFEDLTEVDKKIADYILNNTEAISKLSVSELASNS
                     KTSTASIVRFSRKMGYSGFGDLKIEIAKDLMGKENEYTYVDENYDCNIDSVINKITNK
                     NIETINQTRLLNEKDIIKEAVEQIIKAKNVYIFGVGGSALVALDLQMKLLRINKQAFT
                     SLDSHTQLMVSSNVDKEDIAIAISYSGESKEVIKSIENAKLKGCKVICITKYSDNHLS
                     KISDLKLVVPNIEKRLREGAISSRIAMLTLIDIIYISIIQENLNEAEQKLQETKRILD
                     YLNINNA"
     gene            9684..10715
                     /locus_tag="PC466_002798"
     CDS             9684..10715
                     /locus_tag="PC466_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="HDF2770164.1"
                     /translation="MKKIRKLATKLLITTIVLVSGMSMTVYGMTAKEVTAKTPKSYVT
                     GTNSVYGPKLSQAQLNSVAQATADFMNNKITKNMTTDAKILVAYNHIKNNTTYVDWNA
                     VEGANTAYTLVTKKGACSGMARSMKALCDAMGIESYYVHSTSNDHQWNLIRFGDGRLY
                     HVDIDANKSAGKDIIYKSLSHPLPFDKTAYPTVGAVAQTQKPALPGKHTMLPHQDGAK
                     VVGKFGDIKDKHVMYEGVRCVVINSSVNTVTFLGSKSNLDPSNLTIAVIGFMNTPYGM
                     FALAPEGEPVEYPFKYDKPFSLDFSGKNRSGAELAKYCKKNDVTIKIEITDEKANIGL
                     GQIMYIRYE"
     gene            complement(10831..11805)
                     /locus_tag="PC466_002799"
     CDS             complement(10831..11805)
                     /locus_tag="PC466_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770165.1"
                     /translation="MNNINSLKVIKLSLGCSLAIFIAWLLKLEYSMVAGVIVLLTVKD
                     TKRETLKGSIGKIYGFLLCTIFSYLCFNILGYNLTSFSIFIFIIIPLCFLLNIQDVIA
                     MCVVIASHYYLQGETSIKWILNEAGIFAVGTGIGVLINMYIPTNIHKIHEVQKKLQEE
                     VSIVLIDIADIIVNPKKENGYSRDLYKLNSLIDSSISETYDNINNTLLSDTRFFLEHM
                     DIIKSQRDILENLYSYVSQLNSTPPQAHILSAFIHKIGYTEFEAETGNLLLEELKRLM
                     LSMKNHPLPVDRTEFENRAILFLCLTELKQFLVNRKHAQMLRDNNFYK"
     gene            12261..13142
                     /locus_tag="PC466_002800"
     CDS             12261..13142
                     /locus_tag="PC466_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline iminopeptidase-family hydrolase"
                     /protein_id="HDF2770166.1"
                     /translation="MKITEGYMPFKGFKTYYRIVGENTEGKKPLVLLHGGPGSTHNYF
                     EVLDKIAESGRQVIMYDQIGCGNSFVEGHPELFNADTWIEELIELRKHLGLDEIHLLG
                     QSWGGMQAIWYAIEYKPKGIKSYILSSTLSSAKLWEKEQKRRISYMSEVDQKALLDAV
                     NTGDYSNKEYNDALERFMEMYCAGEVTEDSPECLRRPKKSGSEAYIVGWGQNEFSPTG
                     TLSGYEFTDRLHEIKEPCLVTSGAIDLCSPYIAKTMYDRIPNSKWELFEYSRHMPFVE
                     ENEKYIKVLTEWLNAND"
     gene            13524..14327
                     /locus_tag="PC466_002801"
     CDS             13524..14327
                     /locus_tag="PC466_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770167.1"
                     /translation="MEKLRVIEMIKNNPNIIATIDNPTDEMKLLAIKENGLVLEYINN
                     PTREMQELAIDNNIRAIKFIDNPTEDMMIKAVNEGWSILDYIKNPTDKVIEMAINQAG
                     WAIKYAKNPSEELQLLAVRKNYDSIKFIKQPYESVQEEAVRISYDALRYIDSPSYNAE
                     LIAIKNNEAAISFITDLDKNKMLEFLKVNILVIKYILKKVSKDELESVLKEVLSKEDV
                     EEKYIRDFLNCSVIDRNSESIPIDKIMFIYKYGSKTAKKIAVDEKLKIM"
     gene            14339..15469
                     /locus_tag="PC466_002802"
     CDS             14339..15469
                     /locus_tag="PC466_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF2770168.1"
                     /translation="MNFIDTLKSVDLILSTGEVPLIVGESGIGKTALANKLAKENDWS
                     LIVIDGNLLKEGEIGGLPTIESYVGVNSNGYKTEKKTTVYAVHNKLREIDEEISKSKT
                     VLLFIDEINRCEHTVQQELMNLILNREINGYKLHDDVKILAAMNPSSKYGSDFDYQVV
                     DMDAAQENRFVWLNMESDHTQWIKWAIDEGIERKVIEFISTFPEYLHKINEDDVRATP
                     RSYERVSKIYKVYKEKNNSIPRAVFLNVVKGNVGKVIAEEFISFIESNSEPLISYEDV
                     FLRESIDEPIVERVKNESHTRLYLSAMNILKDLELNIKNDKYESNHYINRFIEFLKMY
                     PVDLMIGIMKDIRNSYIEVYKKAIENEGFVKSYFESYSLIRG"
     gene            15473..16882
                     /locus_tag="PC466_002803"
     CDS             15473..16882
                     /locus_tag="PC466_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770169.1"
                     /translation="MENYFDKQAKELYNKASEIINTHSMLKANRANEKFDMDIPQDFK
                     YEFFSLVDKVNLSLMEEEDNFYGYFLFQMSREIRFDISSPTGVNFKGAKYVIYFNPII
                     FLTLDIKQMETTIKHEIHHILSMHLMRAKELKGKYSTLAINMAMDIVVNKFLNNLPPY
                     ATTLEWVNLKYSLKLEPYEPFEYYVEKIQTELDLMEVDEDGEEDDSDKYGDVEIDYSP
                     ERTHDIWDESNEIDKNTLREFTEKFINSSQKGKVPAYLESMISSLKNSKGELPWNLYL
                     NRIMGTVENNKKKTITRRNRRQPNRLDLRGELRSHKAEIAVALDVSGSISDEEFKQAI
                     KEVLSIVKNYNHEITIIECDNEIRRVYKVRTEKDIKDRIRIGGGTRFSPVFEYANNKK
                     INLLVYFTDGKGENKLQVIPRGYKILWVISGRGDKISLKEPYGAVKKLTKVKTNDEIL
                     EINDVRNDGYSMNSQAPIL"
     gene            17093..17602
                     /locus_tag="PC466_002804"
     CDS             17093..17602
                     /locus_tag="PC466_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CarD family transcriptional regulator"
                     /protein_id="HDF2770170.1"
                     /translation="MVMFLFKIDDYIMYGMTGVCKVMDITNERFTNGIKKEYYVLSPI
                     YSNNTVIKIPVDNEKVPMRKLLSKINVLSLINDIPNMDTSWIDNEKLRSEQFKKILRG
                     GKCEELIKLVRSIDNNREYVKSIGKKTHQADDNIMKEAERLLSEEFATILDISPNEVS
                     SYISSHIPQ"
BASE COUNT         7338 a         1882 c         3221 g         5936 t
ORIGIN      
        1 tatataaatt ttagaaatag ttatataaat ttatataatt gtatagaaaa tagtggtgaa
       61 atagacagtt atttaattga tggacaatct tttgaagaaa atctaataaa agatattata
      121 gaaaacttaa aaataaaaaa taatagtgac atagagactt ataaacaatc attaaaagaa
      181 ttagatgatt acatagctaa atgggttcat gaaataaaaa ttccaatatc ttctttaagt
      241 ataattacag ataggttaag tagcatagaa gatagtttgg atattaagaa tcaggttgca
      301 aagataaatt ttttagtaaa ctctattttg tatagtagta gaagcaacac tatgtttgaa
      361 gatgtattta taaataaatt taatttagaa aaattggtaa aaatgtctat aaaaaataat
      421 tcatttttgc ttataaaaaa taatgtagaa gttagtttga atgaattaga aaatgatgtt
      481 tacacagatt ctaaatgcat gtcatatgtt ttagaccaaa ttattaataa tgctataaag
      541 tattcaaagg aagttggtaa gattgaattt aattcaaaaa agttagaaaa tggagtggta
      601 ttatctataa aagattttgg tataggtata aatgaggaag atatatctag ggtttttgac
      661 aagggattta cggggaaaaa tggaagaaat caattgtata agtctactgg aatggggatg
      721 tattttgtaa agaaaatgat agatagttta gggcatgaga ttgaggtatg ttcgaaaatt
      781 ggttcatata caatttttaa tatctacttt tatgatatat cggattattt aagcctagat
      841 agttaggtta ttagactata aaatctatca tcatatacaa atcgacatat acaataagaa
      901 taaatttagt tcttgaaaat agtgaagatt taattagtgc cttaaatgat gttctatcta
      961 tattataaaa taataattat tatatatgaa aaacatatca gataggtacc tggtatgttt
     1021 tttatttgta gtaactattt taatatggtt tttggagaga gaatatgttt tgtttgtgaa
     1081 aaaaaattac atgcattaca ttgacactga aaataaatta atgtaagatt tagctaaggt
     1141 aaaaaacgtg tataagatta actcgattaa tttcgtaaga gtaaattatc gcaattaaag
     1201 atgaaataag attaattcta aaattattaa acttaatacc ttgatttggg gaggaataac
     1261 tataaactta aaaggatgat aactatgtat agtgtaggtt taatgtcagg aacttcctta
     1321 gatggagttg atgcagtact agctgaaatt agtgggaatg gtagaaatac taaagttaag
     1381 caaatagaat ttataactct agaaattcct aaagatataa aagacgaaat aagaaagtgc
     1441 tgtatagaag aggaatcgag tgttgattta atctgtagct taaattttaa gcttggatat
     1501 ttatttagta aagctgtaaa atcagtgtgt cataaagcaa actttcatat agcaaatttg
     1561 gattttatcg catctcatgg tcaaacaatc tttcatatac caagaagtta taataatttt
     1621 gtatcttcaa cgcttcaaat aggtgaacca gcaattatag catatgaaac aaatacaaag
     1681 gtaatatcta attttagagt aatggatata gcagcaggtg gagaaggtgc tccattagta
     1741 ccatatagtg aatttttatt atatagtgat aaaaataaaa atttagcact tcaaaatatt
     1801 ggtggaatag gaaatattac tataatacct aaatcatgta acatagatga tgtatttgca
     1861 tttgatacag gaccaggaaa tatgataata gatggagtat gtcaaagatt atttaataga
     1921 aagtatgata aaaatggata ctttgcatca aaaggtaaaa ttaatgaaga aatgttaaaa
     1981 gatttgatga gtcataagta tcttagtcaa gcgccaccta aaagcactgg aagagaggta
     2041 tttggacaag tctatttgga taacatgctt aacaaatata aacatgtaga taaatatgat
     2101 ttgatagcaa cagtaactat gtttacggca aaagctatat attataatta taaaaacttc
     2161 atacttccaa aggttaatgt agatacttta ttaattggag gtggaggagt tcataatcta
     2221 actttaatag gatatataaa agagttatta ttagaggttg aagtattaac tcaagatgaa
     2281 tatgggtatt cttctgatgc aaaggaggct ttggcatttg taatcttggg caatgaaaca
     2341 ttaaataatt ctttttctaa tgtaatatct gcaacagggg ctaaaaataa agttatttta
     2401 gggaatataa cacctaaacc ttttggaggt aaatgacatg tctaataata aaaaaaagaa
     2461 aagaaagaaa aataataatt ataaaaatgc aaaaagtaat aaaaatacta agaaagaaat
     2521 ggagaaaaat caaagaacag attataatat tccaactata agttttaaaa gtggattaat
     2581 actaatagtt tcatctctag taagtactgt agtttttcct ttgttattat ctatatttgg
     2641 aatagataat agatttggag ttgttatagg aaattcatta attacatctt ttgcagttgc
     2701 atatacaaga tactttgttg aaactaagag aggtttttct ttgggatttt ttagactgta
     2761 tattttattt gttttatcat ttgcaataat aggttacttc tggatatata aaggaataca
     2821 tatttaaaaa agtattgaga ctattttatg ttaataaaag atagtctttt ttctttttta
     2881 agaaaagata tgagtatttt aagtagtgtg taattttaga caaaagaatg attagataaa
     2941 taaagcaatt aaagcaagat ataaatgcat gaaataaaat tacaattaaa aatgtaaaat
     3001 atgaaaaaat atatacaaac gtattcctgt aatcaaaaat acatgctata atgattgaaa
     3061 agaaataaaa aaacaggggg aatcaatatg agagtattat ttgtttgttc atcagggatg
     3121 tcaagtgcta tagcagttaa tgcattacaa aaagaaggag caaaaaatgg aatagatata
     3181 gatgttttgg ctgttggtac tcaagagttt gagaatgaag ttaaaaatgg atgggatatt
     3241 gctatggtag ctccacaagt cagacataga tttgactatt taaaagcttt tgctgatgag
     3301 gctagtgtac catgtgcatt aatacaagca caagcttata gtccattagg aggaccaaag
     3361 ttattaaaac aagttcaaga gttgttgagt aaatagtagt tgcagtgttg ttaggttaga
     3421 agaaagttaa ttttataaaa attttaatga taataaaaat aaatattaat taaggagaga
     3481 aaagatgcta gataaattta cagaattttt agacagtaaa ttatcaactt ctatggccag
     3541 attggcagaa caacgtcact taagagctgt aagagatgga atcgtagctt cattaccact
     3601 tataatagtt gggtcatttt tcttgatatt agcatttcct ccattaccag attcatgggg
     3661 ggtaactcag tatctaaagg aaaatgcagt tacaatatta ctaccatata gaatgacatt
     3721 ttttattata tcagtatatt ctacatttgg cataggttat agtttggcaa agtcatataa
     3781 gttagatgga ttgacaggag gtttattagc tacagctaca ttccttttga caatagttcc
     3841 tactgcaata gagggtctta cccctgattt attaaagata gttgaaaaga gtccagaact
     3901 tttagcttgg tataattcaa ttcctcaagg atggcaaatg ccaatggcta atcttggtgg
     3961 aggttcaatg tttgttgcta ttgtaacatc tataataggt gttgagattt atagatttac
     4021 tgacaaatct aaattcaaga taaccatgcc agaagcagtt ccagcatcag tcacaaggtc
     4081 ttttgaagct ctgacaccag ccgcattaat aataatttta atggctattg ttacttattt
     4141 cctagggttt gattggcatg gcttcatagc taaattagta actccattag tttcagccac
     4201 tgacacatta ccatcagtaa ttatactaat atttttaata acgttttttt ggtcatttgg
     4261 aatacatggt gtatcaataa taggttcatt ggcaagacct ttatggatac aattattaga
     4321 tgctaataca gcttcatatg ctgcgggtca agcagttcca ggtattgctg ctgaaccctt
     4381 ttttcaatgg tttatatgga ttggaggttc tggagctaca ataggcttag ctttacttct
     4441 tgcatttaga gcaaaatcag cttatggaaa gtctttagga aaagcaactg taataccagc
     4501 aatattcaat ataaatgaac caataatatt tggagcacca atagtattaa acccaatatt
     4561 aataatacca tttgttgtgg caccaatagt aatggcaaca gtttcatggt ttgctatgag
     4621 tgctaattta gtatccagag tagtagttac tgctccttgg acattaccag gaccagtagg
     4681 ggcatattta gccactggtg gagattggag agcttcagtt cttaacttat tatgtatagc
     4741 tatatcaata ataatttact atccatttgt caagatgtac gataagagat tgcttcatga
     4801 agaaaaagtt gaagagcaag aagcttatta attagaaact atattggaaa ttaaaaacta
     4861 tattagatta gtataaattt caaagtataa cagttatgaa ataagtaacg aagatatttt
     4921 gttgattgtt tataaaaaaa gaaaaggtaa acttttcttt ttttataaat atatatgaaa
     4981 ctttttttca ccaaattttt aaaaaagttt cgtgtaattc gaaataaatt taaacacata
     5041 taggatataa ggagatgaca cagatgggaa gattaggaat atcaatttat ccagaaaaaa
     5101 caacatctaa ggaaatatat gattatatag ataaagctgc tgaaaatgga tttacacgta
     5161 tattttcatg tttattatca gttaaagata ctaaagaaaa tataattaaa aaatttaaaa
     5221 gtataaatga atacgctaag tttaaaggtt ttgaggtaat acttgatgta aatcccagag
     5281 tatttggtga attagaaata agctacaaag atttgacttt ttttaaaaag acgaaggcag
     5341 acggaataag gcttgatatg ggatttacag gttctgaaaa ggccttaatg acttttaatc
     5401 ctcaaaatct taaaatagaa atcaatatga gtaataatac taattatata gatacaataa
     5461 tggactacca accaaataaa gaaaatttga caggatgtca taacttttat ccacatagat
     5521 atagtggatt aaatttagaa cactttataa aatgtacaga aagatttaat aagtatggat
     5581 taagaacagc agtttttgta acaagtcaaa atgaaaccac atttggacca tggcctgtaa
     5641 ctgatgggct tccaacaatt gagatgcaca gaaatctacc tatagatatt caagtaaagc
     5701 atataatagc tatgaataat ataaatgata taataatatc aaattgttat ccaacatatg
     5761 aggagctaaa ggtattaggt tctatgagaa aagatatggt tacatttgat gtagcaatag
     5821 aggaaaatat acgagaagtt gagaagaaga tactctttga agaaatacat tttaatagag
     5881 gggatatatc tgacagtctg ataaggtcta ctcaatctcg tgttaaatat aaaggataca
     5941 aatttgaact atttaatact cctaaaataa taaaaagagg agatatagta attgaaagta
     6001 gtgaatatgg tcattatgca ggggagttac aaatagcctt gactgatatg aaaaacagtg
     6061 gtaaatcgaa tgtagtagga tatataagaa aagaagaatt atttatatta gattatatta
     6121 aaccatggca aaagtttgat tttaaaccct caacaaaata atttattatg aaaatattaa
     6181 tttattataa aaatataatt atgaaagttg gagttaaaat gtgtttaaaa atttaatatt
     6241 aagaaaatga ggaaatgata tgttaataaa aactttagaa aatttagtta cagaaggtag
     6301 aaataagaat acattgcaaa tagataaaga agatacatta ggcataatag aattaataaa
     6361 taacgaagat aaaactgtag cctatgctgt tgaagaacaa aaggagagta tagcaaaagc
     6421 tgttaatata atagtagata gaatgaagca gggaggtaga ttattctata taggagcagg
     6481 taccagtggg aggataggaa tactagatgc cacagaatgt cctccaactt acggagtgga
     6541 ttttgagctt gttcaagcta taatagctgg tggaaatcaa gcaatattta aagcaataga
     6601 aggtgctgaa gatgataaag aacttggaaa gcaagatata atagatagag gagttacatc
     6661 taaggatgtt atatgtggta tagctgcatc aggaaggact ccttatgtta taggtgcaat
     6721 ggagtatgct aaggaattgg ggtgtgcagt actatcaata actatgaatc cgaatagtga
     6781 aatgagtaaa aaagcggatt taccaataaa cattatagta ggggcagaag taataatggg
     6841 ttcaactaga atgaaaagtg gtacagctca aaaaatggta tgtaatatgt taacaacagc
     6901 ttctatggtt aagatgggaa aagtatactc aaacttgatg gtagatgtta agacatcaaa
     6961 tgaaaagttg gttgaaagag caaaaagaat aataatgata gctacaaatg taaaatatga
     7021 cgttgcagaa aaattcttag aagaagcaga taatagagtt aaattggcta tatttatgat
     7081 aaaaagtggt ttagataagg atagtgcaaa gagtatccta gatagacaag aaggttatat
     7141 aagtgaagct ttaaaatcaa tagaaaaatt gtaaaataaa taatagtact gataaccttt
     7201 caatattaaa aaaacagcat tggaaggtta tttttagata ttaagtattg aaagaattat
     7261 taaagatatt gtaggaggat agtatgtatt ttttaggtgt agatggtgga ggaacgaaaa
     7321 caacatttac attagtagat gaagaattaa atatagtagg aaccataacc aaaggaactt
     7381 gtcattataa tcaaatagga tttgataatc taacgaaatt attaataact gggttggaag
     7441 aagtttgtaa agatgctaag ataaatgtag aagaaataac gtatgcattt gttggacttg
     7501 ctggatatgg aaaaataaaa gaagtattgt atgcattaga agtagcaaca aaaaatgcat
     7561 atagtcatat aaattatact ctaggtaatg atgtagaaat agcattagca ggttctttaa
     7621 atggggaaaa aggtataaat ataattgcag gtactggttc aatagcacag gctttagata
     7681 aagatgggaa tcttcacaga tgtggaggat ggggctatgt attaggagat gaaggttcag
     7741 cgtattatat aggaatggct accttaaaaa tgttcacaat gcagtctgat ggaaggtgtt
     7801 caaagacaaa attatatgat ttaataaaaa gacatcttaa tatagagaat gattatgaca
     7861 taataaaata tgtaaatgat ggaatacaag gagatagaat agaaatagca aagtttgcta
     7921 cgatatgttt aaaagcagtt attgaaggtg ataatactgc tagtaaaata tttgatgatg
     7981 cagcttatga attaagtagg cttataatag gattagagca tcattttgaa caaggtacaa
     8041 agataaaggt atcttattca ggtggagtgt ttaagtcagg agatttaata ttagagccac
     8101 ttaaaaaata tttgaataaa acgagatttg gtatagtgag accagtgttg actccagatt
     8161 taggagcatg tttacttgct aagaagaaat attatagtaa ataggtagag gtggtagagt
     8221 atgagttgca ttttaaaatt aaaacagata tttgaagatt taacggaagt agataaaaaa
     8281 atagctgatt acatacttaa taatacagag gctataagta agctttctgt atcagaattg
     8341 gcgtcaaact caaaaacaag tacagcaagt atagttaggt tttctagaaa aatgggatat
     8401 tcgggttttg gggatttaaa aattgagata gctaaagatt tgatgggcaa agaaaatgaa
     8461 tacacatatg tagatgaaaa ctatgattgt aatatagata gtgttataaa caaaattaca
     8521 aacaaaaaca tagagactat caaccaaaca aggttgttga atgaaaaaga tataataaaa
     8581 gaagcagttg aacagataat aaaggctaaa aatgtatata tatttggagt aggtggttcg
     8641 gctttagttg cactagattt acagatgaaa cttttaagga taaataaaca ggcatttacc
     8701 tctttagata gtcatacaca acttatggta tcttcaaatg tagataaaga agatatagct
     8761 atagcaatat cttactctgg agaatcaaaa gaagtaataa agtctataga aaatgcaaaa
     8821 ttaaaaggat gtaaggtcat ttgtataact aaatatagtg acaatcatct tagtaagatt
     8881 agtgatttaa agctagtagt accaaatata gaaaaaaggc ttagagaagg agctatttct
     8941 tcaagaatag caatgcttac gttgatagat ataatatata tttctataat tcaagaaaac
     9001 ttaaatgagg cagaacagaa actacaagaa acaaaaagga tacttgatta tttaaatatt
     9061 aataatgctt aaaactaggt tatatatcaa ctaaacaaat aagttagact ataagcgtaa
     9121 gtcaataaga aatagataaa tatctaaaat attgacttac ttaataataa tatatagcat
     9181 ttttataata caaatgagtt gtcttaaaat tgattttttt taatcaaatt ttaagttcaa
     9241 ctcctttttt atatttttat agatatatcc tatattttcc cagaaaacgt attgaatata
     9301 caaattataa gaagtataat gttgttggga gagaatgtat gaaatgtata caaagttgat
     9361 tttaactgta ttattgataa ttctctttac tcttaccatt attaatgatt gaagacaatg
     9421 gtatttatta taggtcaaag attccgaata tattaatcat catcattttc tcaaactaac
     9481 agcaaacacc ctgatttgcg agttgtattg tatacaaatt atctagaaaa tatctattag
     9541 attttccatg aaatttaaat atttcacgaa cgtataaatg aagaaacata catattgaca
     9601 atccaccttt ttaaatccca aatgaacttt attaatggta gagaatagga agtaacaata
     9661 ttttataaag gagaatacta agtatgaaga aaattaggaa gttagctacc aagttattga
     9721 ttacaacaat tgttttagtc tcaggtatga gtatgacagt ttatggtatg acagccaaag
     9781 aggtaacagc aaaaacacca aaaagctatg tcactggaac caatagcgta tatggtccaa
     9841 agctgtcaca agcccaacta aactcagtag cacaagcaac agcagatttt atgaacaata
     9901 aaattacaaa gaacatgact acagacgcta agattttagt tgcctataat cacattaaaa
     9961 ataacacaac atatgttgac tggaatgcag tagaaggagc gaatactgcc tatacattgg
    10021 ttactaaaaa aggtgcatgt tcaggaatgg ctaggagcat gaaagctttg tgtgacgcta
    10081 tgggaattga atcttattat gtacacagca catcaaatga ccaccagtgg aatcttatac
    10141 gttttggtga tgggcgtttg tatcatgtag atattgatgc taataaatca gcaggaaagg
    10201 atatcatata caagagtctt agccacccat taccatttga taagacagca tatccaacag
    10261 ttggagcagt agcacaaacg caaaaaccag cactacctgg gaagcacact atgttaccac
    10321 atcaagacgg ggcaaaggtt gttggaaaat ttggagatat aaaggataaa catgtaatgt
    10381 atgaaggtgt tagatgtgtt gtaattaatt catcagtgaa tacagttaca tttctaggta
    10441 gtaaatcaaa tttagaccca tcaaatctta caattgctgt aataggattt atgaacacac
    10501 catatgggat gtttgcatta gcaccagaag gtgaacctgt tgaatatcct tttaaatatg
    10561 ataagccatt ttctttagat tttagtggta aaaatcgttc tggtgcagaa ttagcaaagt
    10621 actgtaaaaa aaatgatgtg actattaaaa tagaaatcac tgatgaaaaa gctaatattg
    10681 gacttggtca aataatgtat attcgatatg aataatgatt taatcatgac agtagaataa
    10741 gttataaaca tcgcgccctc ttactagggg cgcatttaat attatatctg atattttgta
    10801 gtcaggtcaa ctgctggatt tctcaccttt ttatttataa aaattattat ctctaagcat
    10861 ctgagcatgt ttacgattaa ctaaaaattg ttttaactca gtcaagcata ggaataaaat
    10921 agctctgttt tcaaactctg ttctgtcaac aggtagagga tggtttttca tactaagcat
    10981 taatctcttc aattcttcaa gaagaagatt gcctgtttca gcttcaaatt cagtataacc
    11041 tattttatgt atgaaagcag atagaatgtg agcttgtggt ggtgtagaat ttagttgaga
    11101 tacataacta tacaaatttt ctaagatatc ccgttggctt tttataatat ccatatgttc
    11161 taagaagaat ctagtatcac ttaataaagt attattaata ttatcgtaag tttcagaaat
    11221 actgctgtca ataagtgaat ttaatttata taaatctcta ctatatccat tttctttttt
    11281 aggatttaca ataatatctg caatgtctat aagtacaata ctcacttctt cctgtaactt
    11341 tttttgaact tcatggattt tatgtatatt tgttggaata tacatattta ttaagacacc
    11401 tattccagtt cctactgcaa atattccagc ttcatttaaa atccatttga tagaagtttc
    11461 tccttgaagg tagtaatggg atgctatgac tacacacata gcaataacat cttgaatatt
    11521 taacaaaaaa caaagtggta taattataaa tataaatatt gaaaatgaag tcaaattata
    11581 tcctaaaata ttaaaacata aatatgaaaa aatagtacat aaaagaaaac cataaatctt
    11641 tccaatggag cctttaagag tttctctttt agtgtccttt actgtaagta gtactataac
    11701 tccagcaacc attgaatatt ctaattttaa tagccaagca atgaatatag caagagaaca
    11761 tccaagagat aattttatta ctttaagtga attaatatta ttcaaatgca aacctcctgt
    11821 aaatcaatat aataaaattc taacataaaa ctaatattgc ttgaaaggta agtaactata
    11881 cttaattatt ttattgccct atttgtttag atacaatcaa tataatttta ttttatgaaa
    11941 attttttgta aaattttaaa tttagagact aacatgagac cacaaagagg aagtttatta
    12001 taagaagaaa acttaaaatt gattttaaat agcaaatgaa aataatcaaa tatgtatata
    12061 ctattattaa aaaataaaat tatatagtta atataatttt ataattggtt tagtatagag
    12121 atttttaact tttatgttat actatttata aaagtaggta taaagattaa aagacataat
    12181 taaatacgta tgagaggttt taaatagtat tgttaatgaa cttgattatt gtttataatt
    12241 acaaattgga ggagataaat atgaaaatta ctgaaggata tatgcctttt aaaggtttta
    12301 aaacgtatta ccgtatagta ggagaaaata cggaagggaa gaagccatta gtattacttc
    12361 atggaggtcc aggttctaca cacaactatt ttgaggtatt ggataagata gctgaaagtg
    12421 gtagacaagt aataatgtat gaccaaattg gttgtggaaa ttcctttgta gaagggcatc
    12481 ctgagttatt taatgcagat acttggatag aggagcttat tgaactaaga aaacatctag
    12541 gacttgatga aattcatctg ttaggtcaat cttggggagg tatgcaggct atttggtatg
    12601 ctattgaata taaaccaaaa ggtattaagt cttacatcct ttcatctact ctttcttctg
    12661 caaaactttg ggagaaagaa caaaaaagaa gaatatcata tatgagtgag gttgaccaaa
    12721 aagcattgct tgatgcagta aatactggag attactctaa taaagaatat aatgatgcat
    12781 tagaaagatt tatggaaatg tattgtgcag gtgaagtgac agaagattct ccagagtgcc
    12841 tgagaagacc taaaaaatca ggttctgaag catatattgt aggatgggga caaaatgaat
    12901 tttctcctac aggaactctt tctggatatg aatttacaga tagattacat gaaataaaag
    12961 agccttgtct agtaactagt ggagcaatag atttatgttc gccatatatt gcaaagacta
    13021 tgtatgatag aatacctaat agtaagtggg agttatttga gtattcaaga catatgccat
    13081 tcgttgaaga aaatgagaaa tatataaaag tcttaactga gtggttgaat gcgaacgatt
    13141 aaaaactata taaatttata taaagaaatg agtgtctcaa aatgaacttt ttagttcatt
    13201 aggcactctt tttgcatgaa atcaaatata ttttcattat ttgaacgata aaatgaggct
    13261 tatatctatt ttgggaaagt aattttttat tactagcgtt agattctaat ctaattgtat
    13321 acttattgaa ataatagaaa tatattggtg tttataactt aattttattg ttttttagaa
    13381 atttttttat atattggtat aattattctg tttaaatttg attaaaaagt atattaatta
    13441 taataagaaa caattatata aataggaata gattattata attaatatag atataaaaat
    13501 aattatagaa agaaaggcac attatggaaa aattgagagt tattgaaatg ataaaaaata
    13561 atcccaatat tatagctaca atagataatc caactgatga aatgaaattg ttagctatta
    13621 aagaaaatgg gcttgtacta gaatatataa ataatccaac cagagagatg caagaactag
    13681 caatagataa taatattaga gcaattaaat ttatagataa tccaacagaa gatatgatga
    13741 taaaagcagt aaatgaggga tggagtatac tggattatat caaaaaccca actgataaag
    13801 ttattgaaat ggctataaat caagcaggat gggcaattaa atatgctaaa aatccaagtg
    13861 aagaattaca actgttagca gtaagaaaaa attatgattc gataaagttt ataaaacaac
    13921 cttatgaaag tgtacaagag gaggcagtaa gaataagtta tgatgccttg agatatatag
    13981 attcacctag ttataatgca gaacttatag ctataaaaaa taatgaagca gctattagct
    14041 ttataactga tttagataaa aataaaatgt tggaattttt aaaagtgaat attttagtga
    14101 ttaagtacat tctgaaaaaa gtatctaaag atgaattaga gagtgtatta aaagaagtat
    14161 tatccaaaga agatgttgag gaaaagtata ttagagattt tttgaattgt agtgttatag
    14221 atagaaatag cgaaagtata ccaatagata aaattatgtt tatttataaa tatggaagta
    14281 agacagcaaa aaaaatagct gtagatgaga aattaaagat tatgtaggag agagaaaaat
    14341 gaattttata gacacattaa aaagcgttga cttaatatta tccactggag aagtaccttt
    14401 aatagtaggt gaaagtggaa taggaaaaac agctttagca aataagcttg ccaaagaaaa
    14461 tgattggagt ttaattgtta ttgatggaaa cttacttaaa gagggtgaaa taggtggtct
    14521 tccaactata gaatcttatg taggagttaa ttctaatgga tataagactg aaaagaaaac
    14581 aacagtgtat gctgttcata acaaattaag agaaattgat gaagagatat ctaaaagtaa
    14641 gacagttctt ttatttatag atgagataaa tcgttgtgag catacagtac agcaagaact
    14701 tatgaattta attttaaata gagaaattaa tggatataaa ctgcatgatg atgtaaagat
    14761 tttagcagca atgaatccat caagtaaata tggttcagat tttgattatc aagtggtaga
    14821 tatggatgca gcccaagaaa ataggtttgt ttggttaaat atggagagtg accatacaca
    14881 atggataaaa tgggcaatag atgagggtat tgaaagaaaa gttatcgagt ttatttccac
    14941 ttttccagaa tatctgcata aaataaatga agatgatgta agagctactc ctagaagtta
    15001 tgagagagta tctaaaattt ataaagttta taaagaaaaa aataattcta ttcctagagc
    15061 agtattttta aatgttgtaa agggtaatgt aggtaaagtt attgcagaag aatttataag
    15121 ttttattgaa tcaaactctg aaccattaat atcctatgaa gatgtttttt taagagaatc
    15181 tattgatgag cccattgtag aaagagtaaa aaatgagagt catacaagac tttatctatc
    15241 agctatgaac attctaaaag acttagaatt aaatattaag aatgataaat atgaatcaaa
    15301 ccactatatt aatagattta ttgaattttt aaaaatgtat cctgtagatt taatgatagg
    15361 tattatgaag gatattagaa acagttatat tgaagtatat aaaaaagcca tagaaaatga
    15421 aggttttgta aaatcatatt ttgaatctta tagcttaata aggggataat gtatggaaaa
    15481 ttattttgat aaacaagcaa aagagcttta taataaagca agtgaaatta taaatactca
    15541 ttctatgcta aaggcaaatc gtgctaatga gaaatttgat atggatatac cacaagattt
    15601 taagtatgag ttttttagtc ttgtagataa agtgaattta agtcttatgg aagaagaaga
    15661 taatttttat ggatattttt tgtttcagat gtcaagagaa ataagatttg atataagtag
    15721 tcctacaggc gtgaatttta agggagctaa atatgttata tattttaatc caataatctt
    15781 tttaacgctt gacataaagc aaatggagac tacaattaaa catgaaattc atcatatatt
    15841 atctatgcat ttgatgagag caaaggagtt aaaaggaaag tatagtacat tggcaattaa
    15901 tatggcaatg gatatagtag taaataaatt tctaaacaat ttaccaccat atgcaactac
    15961 cttagagtgg gtaaatttaa aatattcctt aaaacttgaa ccatatgaac cttttgaata
    16021 ttatgtagaa aagattcaga ctgaattaga tttgatggaa gtggatgaag atggtgagga
    16081 agatgatagt gataaatatg gagatgtaga aattgattat agccccgaaa gaactcatga
    16141 tatatgggat gaatccaatg agatagataa aaataccctt agagaattta ctgaaaaatt
    16201 tattaacagt tctcaaaaag gtaaagttcc tgcttattta gaaagtatga tatcatcact
    16261 taaaaatagt aagggtgaat tgccatggaa tttatatctt aatagaataa tgggaacagt
    16321 tgaaaataat aaaaagaaga ctataacaag aagaaataga agacaaccaa atcgtttaga
    16381 tttgagggga gaacttagaa gtcataaggc agaaatagca gttgcacttg atgtaagtgg
    16441 aagtattagt gatgaagaat ttaaacaagc tattaaagaa gttcttagta tagtgaaaaa
    16501 ctataatcat gaaattacaa ttatagaatg tgataatgaa attagacgtg tatataaagt
    16561 gagaactgaa aaagatataa aagatagaat taggataggt ggaggtacta gattttctcc
    16621 agtctttgag tatgctaata ataaaaagat taatttgtta gtctacttta ctgatggtaa
    16681 aggtgaaaat aaactacaag taatacctag agggtataaa attttatggg ttatttctgg
    16741 aagaggagat aaaatttcat taaaagaacc ttatggagca gttaaaaaac ttactaaggt
    16801 taaaacaaat gatgaaatat tagaaataaa tgatgtaaga aatgatgggt actcaatgaa
    16861 tagccaagca ccaattttat aggtattcac aggagataag ctgtattaat ttattttgat
    16921 atgcttgtta taaaaatcta aaaaatacat taatcaatgg ttaatgtatt ttttaatttt
    16981 aataatataa gttttactta catttaagtc ttaaaatgtg ttaaaatata atatatagca
    17041 gatagttttg gcaagatgga tttagttgtc aaaactattt tttttattaa ggatggtgat
    17101 gtttttgttt aagattgatg attatataat gtatggtatg acaggagtct gcaaagtcat
    17161 ggatataaca aatgaacgat ttacaaatgg aataaaaaaa gagtattatg tattgagtcc
    17221 tatttattct aataatacag taataaaaat tcctgtagat aatgaaaaag taccaatgag
    17281 aaagttactt tctaaaatta atgtgctttc attaataaat gatattccta atatggatac
    17341 atcatggata gataatgaaa aattaagaag tgagcaattt aaaaaaatac tcagaggtgg
    17401 taaatgtgaa gagttaataa aattagtaag aagtatagat aataacagag agtatgtaaa
    17461 atctattggt aaaaaaacac atcaagcaga tgataatata atgaaagaag cagaaaggtt
    17521 attaagtgaa gaatttgcaa ctattttaga tatttctcct aatgaagtta gttcatatat
    17581 ttcaagtcat atacctcaat aaagtgtttt agtatccttt atttaatcta ttttaagtat
    17641 tatttatgta tgctggtttt ggtaaaataa aatatataat taaattatat aaaaaattaa
    17701 gaatgattgt attgaagaat tacagaatag tgcggagagc ccactccttt aggtgtgaga
    17761 tggatatcac ttaaagattt aaattgttat tgtagatgtt tttaatataa agcaagatta
    17821 ataagtgtat tgtaagcttt aagtgaaatt gatactataa tgagttactt agattttaaa
    17881 atatataata ttataaaaaa tccttttagg ttttgaatga ataagatgga tactatgttg
    17941 aatagaatcc atcttattta agttttattt atgttgttta tttgtaagca ttatttttgt
    18001 acatgaaaac acagtgtaaa aatatgctta gaattatgaa gttttattaa aaatatattc
    18061 gacaaaataa gactaaaaat attcttaaac ttataactaa gataaatatt gtatatttat
    18121 agtgtagcct gaaaaattgt ggatgtacga aatttattta gtattttatt gaaacaaagt
    18181 agaagaagta ctatagttta tctttgaata gattgttatt ttttagtgaa aaagttatta
    18241 ggttaataca taaatataat agcttataaa tagtttaagc atgttaaaaa agtagttatt
    18301 agagatatat agttacattg cttataagat acttaaaatg atagcattca cttatattta
    18361 gaaaattaag ataaaaa
//
LOCUS       DAMJYN010000074        18234 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.077, whole genome shotgun sequence.
ACCESSION   DAMJYN010000074 DAMJYN010000000
VERSION     DAMJYN010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18234)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18234)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18234
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.077"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(247..1344)
                     /locus_tag="PC466_002805"
     CDS             complement(247..1344)
                     /locus_tag="PC466_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--glyoxylate aminotransferase family
                     protein"
                     /protein_id="HDF2770171.1"
                     /translation="MKKTYLFSPGPVMVTDKVRNSLLHYDICHRGNEFMDLFKDTQQK
                     INKLYNATSNYYSLIVSGSGTSVNECVLSSIFDKEDAVLLVSNGVFGERLEEILFTYN
                     VKTYKPNFEWAEYPDLDILEKYIIENSDIKVIAMVFHETSSGMINPVPELGKLAKKYN
                     KIFFVDAISASAGEYIDVEEFNIDIITGVGGKALGAFPGSAYLCAKESILQNIKENQC
                     KNVYLNLYKHYKVAKSSSQTPNTPNVTLIFALNEALTEFLEDDSKIERYKECSAILRN
                     GMEELGLTFLLPDKYMSNTVTSVFLPKEINVNEFILGLERESGYVVYPGKGKFLDANI
                     FQVANMGEIYPEDCYKFLDILKSKLEIKKVI"
     gene            1637..3163
                     /gene="glpK"
                     /locus_tag="PC466_002806"
     CDS             1637..3163
                     /gene="glpK"
                     /locus_tag="PC466_002806"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HDF2770172.1"
                     /translation="MKYVLAIDQGTTGTRAVLINEKSEFVFSDYMEHTQIYPQSGYVE
                     HDPIEIWNNTKTVSNNVLQQAFESGINESDIKGIGIDNQGETVMLWDKNTGKPLYNAI
                     VWQCRRTYDYVENLKNIPGLENKIIDKTGLIIDPYFSGTKIKWVIDNVKGVKEKIKNG
                     EVLAGTLDSWLIWKMTGGKSFLTDVSTAARTMLFNIRDMDWDRELLDIIGVPRSILAD
                     IMPTSGDFGTTDKEAFCGVSIKITASMVDQPAALFGNGCFEPGMVKNTYGTGCFLYMN
                     IGEELNIAGNGILTTVAWKIGDKVTYAYDGGVYIAGAAIQWLRDGIGVIKNYSETDDM
                     ANSISSTGGVYFVPAFAGIAAPYWDQYARGTMVGITGSTKKEHIVRATLESVALQVKD
                     VVDSMNLASGKEIKMLRVDGGITKNNFTMQFQSDILDIPIEIAENPETTVLGVGYMAG
                     LSCGVWNSIDEIRSEFTISKKYIPNMTKQKREEILLGWNQAVKRAMNWENDTKKVCAN
                     "
     gene            3204..4319
                     /locus_tag="PC466_002807"
     CDS             3204..4319
                     /locus_tag="PC466_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization protein EutH"
                     /protein_id="HDF2770173.1"
                     /translation="MPFDKIILYIMAVGVLLGALDRIIGNKFGLGEQFEEGFNSMGPL
                     ALGMVGIVCLAPVISDVLGPIIIPIFNLCGADPSMFATILANDMGGYPLAMELAHNKE
                     AGMLAGLVVSSMLGCTLVFSIPVGLGLIEYEDRPFFAKGLLIGLITIPFGGIIGGLIA
                     GFNLSMVIINMIPVIILAVILAVGLKFNSTLMINGSLVFGKFISILITIGLGAAAFQE
                     ITGIVLIKGMTPIREGIQVIGSIAIVLLGTFPILHLLVKVLNKPLTIVGGKLGMDATS
                     AAGLVFTLANSIPVYKMMKDMSPKGKVVNTAWLVCATAALGDHLGFTAGVVPEMITPV
                     VIGKLVGGVLAIALAILMTKDLTLEEEQSIKMKKDAV"
     gene            complement(4600..5364)
                     /locus_tag="PC466_002808"
     CDS             complement(4600..5364)
                     /locus_tag="PC466_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HDF2770174.1"
                     /translation="MLPQERYEKILSILKSDNIIKINDIVQMFDISIETARRDLAHME
                     SIGLLKRVYGGAIPVIASSVELNYVKRKKINSNDKKQIAIKCSEFINTNDTIFMDTGT
                     TVLEVSKNLKDKKNLTVITNSILVANELMNTNIKVYVLGGYLRETEGSFSGPLTLSAI
                     EQFNVDKAILGAGGITLENGISDYHLEEALVRKKMIERSRKSIVVVEPPKFGINSFAS
                     VAPIEHIDTIITSASIDHNIIIEFSQKGIPLVIADN"
     gene            5623..5713
                     /locus_tag="PC466_002809"
     tRNA            5623..5713
                     /locus_tag="PC466_002809"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:5657..5659,aa:Ser,seq:gct)
     gene            5801..6589
                     /locus_tag="PC466_002810"
     CDS             5801..6589
                     /locus_tag="PC466_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor protein"
                     /protein_id="HDF2770175.1"
                     /translation="MTTLIFFIVGIASLVVAFVIDGGHIGVLFVFSSALVVFGGTIGA
                     VGASTPFPVFKKSIKIMLLAFKNKKPNNIENIIYFKEIATKARKEGLLSVDKEISEND
                     ELDPFIRKGLELMVDGVDAVTIRNILESQIQITSKRHKEGIAIFDSAGGYAPTLGIIG
                     TVMGLVHILGNLSSNPDALGPQISVAFLATLYGVGSANLIWLPIASKLKAINQQEISE
                     RLLVIEAILSILEGDNSNLMTEKLKIFLNSKELIELEEIGGRAE"
     gene            6610..7350
                     /locus_tag="PC466_002811"
     CDS             6610..7350
                     /locus_tag="PC466_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HDF2770176.1"
                     /translation="MLYDEDEKEENNERWLLTYSDLITLLMIFFVIMYSMSNVDAEKY
                     KQLSQSLNSAFGGSSGVIEGGNSKIEPVVEPGSNDLDSLQNAKFKKVGEEIQKYLNEN
                     GMANSVSLRVQDRGLVISLKDTILFDTGKAVVKDNSRDKIIQIGKMLNEMNSYMRVEG
                     HTDNMSIKNSEFKSNWDLSVMRATNVVQLLIDNAGIAPDKLSAVGYGEFRPIAENSSE
                     EGRSKNRRVDIVLVDSKYDNVENVSKDK"
     gene            7528..7902
                     /locus_tag="PC466_002812"
     CDS             7528..7902
                     /locus_tag="PC466_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770177.1"
                     /translation="MGNKNKNTKYKDKTRERYNKKVENLNKEKLNKDNKQSKKVDKID
                     DIINKSSIVLCVLLVVFSLLYLFKLVQLNIIMILLVITVAIQQGLVSFGAFRNKNYVK
                     ALFSIFVIVCFLIAFKYVVNPV"
     gene            7994..9454
                     /locus_tag="PC466_002813"
     CDS             7994..9454
                     /locus_tag="PC466_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HDF2770178.1"
                     /translation="MNRCKFAKLIITSMIVLLLTGCSLKKEDNYKLDPENPTSIQIWH
                     YYNGQQKMAFDKLVKEFNDTIGAEKGIIVEAFSQGNVVDLSEKVLDSANKKVGSEDVP
                     NIFAAYSDTAYEMDKLGLLVDMDKYISKEELNEYIDEYVEEGRINSKDEFKLFPIAKS
                     TEILMLNKTDWDKFAKATNSNINDIKTIEGLVETSKKYYEWTDSLTKEPNDGKAFFGR
                     DALANYIIIGSKQLGVEIFSVKDGKVTLNIEEKVMKKLWDNFYVPYINGYFASYGKFR
                     SDDAKTGDILALVGSSSGAAYFPDRVMLNDNESYNIETSVFQAPRFKGEGKYAVQQGA
                     GMAVTKSTKEEEYASVEFLKWFTDKEPNIKFSIASGYLPVKKKTNDLNVIKEVMKKDN
                     LSLSDKVEGSIASSIEQINSCNLYTNKAFDGGTKARQILEYSMLDKAKEDSNKINELV
                     KSGTSKKDAVAQFNNDKNFETWFESFKAELENAIKK"
     gene            9507..12383
                     /locus_tag="PC466_002814"
     CDS             9507..12383
                     /locus_tag="PC466_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDF2770179.1"
                     /translation="MENNLRKNNSIMKKMIFPLIIVMLIQTSLFCATILWGGTIKKLN
                     DNSFDILNERVINRKNYIQNEMLQRWSNTSETEATINSSVKKILNEKNALIEDVGNNE
                     EINKDIIKSISNDLIYLLRKNSVTGAFIILNDKNINDKPIDSKGEISRTGLYIRDLDP
                     KFNPNDNSDLLIERGSSDIARSFGISMDSYWEPKFSFKSENEQEGDDFFYKPFRAAID
                     NPNVSSSNLGYWGSKFLLTNAGDRLMTYTVPLIYEDGTVYGVLGIDLSVNYLRELLPY
                     SEINGNKKGNYILGVDRNNDMAFENVISNGYSLKEKFWDGLHSNLEQKESYKNIYKIK
                     NKDNECGNGNIYASVQYLDLYNSNTPFENERWALLGIIEEKSLLSFSKRIEKLVIISI
                     AISLLIGLIGIYIASRLFTKPIVLLANKVRNSNPSKPVNLDKINISEIDELSSAIELL
                     SANVADSSSKLSQIIEMVDMPIGAFELYKNAENVFCTKDKKLKWIRMNIFEDELKVLG
                     VVVDVTKEFIEKRKIEYERDFDILTNLLNRRAFHSQIQEKFKNKDELKIAAFIMWDLD
                     NLKYINDTYGHDAGDEYIRCAADILKKFISWNGIVSRLSGDEFYVFIYGYESKDSIRD
                     IINSVKKQMNNTLLKLHDGTEFKIRASAGISWYPDDSTNYDELMRYADFAMYQIKNTI
                     KGEVSEFDINIYNKDSFLLSNREELNKLIDGQLVEYAFQPIVDCKGKVFAYEALMRPK
                     IKTFSSPIDVIRLARSQSKLYQIERITWFKALKSFKKYKEKFGDCKLFLNSIPNNNLS
                     KVDFEEIEDLYGEYLNRVVLEITENDKINEDFIEKKKAYIDHWNIEIALDDFGTGYNG
                     DAVLLYIMPDYVKIDMSIVRGIDKDENRQKILKNLISYSNERNIKVISEGVETKGEME
                     TLINLGVDYMQGYYISKPSFIPEDISDKIKKELKICHENRNDVV"
     gene            12460..14526
                     /locus_tag="PC466_002815"
     CDS             12460..14526
                     /locus_tag="PC466_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HDF2770180.1"
                     /translation="MVELIITTNIDIRKLNENQLEAVEHIDGPCMILAGPGSGKTRVI
                     TYRIANMVVNKNIAPTRILAISFTKASSIEMKNRALNLSDDIRLNKVTYGTFHSVFFK
                     ILRYFERYNLDSIFDEKSKRMTIKAILKSLNIENADDDENIGQVINEISYVKNELMDK
                     NEFNSEVLTKDEFLKVYNLYEEQKSKVNKIDFDDMLIRTYYLLLNNKSALEMVRNVYK
                     YILIDEFQDINKVQFEVLKLICSPLNNIFAVGDEDQSIYGFRGARPDFLLEFEQYFNN
                     TKKIILDINYRSKSEIVYTANRLIDKNKNRYEKVIKCSQGDGGSVTYISPHDSEEEAL
                     YIAKEIIDEIQKDYVEYSDFAVIYRTNIQSRALVDVFMDMRIPFVVKDSVITIYDHWA
                     SQDILAYLRIGINPKSNKDWLRIINKPFRYISKDSINMVKDEKDFITALINKCNLHPK
                     QVKTINDLEIDLSYLNTLNPKNAISYIRTSLDYDRYVLDYCSNRKIKTNGLVEILNEL
                     ESSATNFNTVTEFLEHIDRVKTELTENNKNKQTEGVIFTTMHSAKGLEFRNVYIIGVN
                     EGTIPHEKSYDICKEEKKEEQLEEERRLMYVAITRAEEKLCISSTLNKYGKKVDKSLF
                     INDIKSPTKKEIDSIGVGDKVYHKKFHEGEIIKKDGIMFTIKFKDRERILDLKTCLLK
                     NIIYTI"
     misc_binding    15118..15328
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            15554..16369
                     /locus_tag="PC466_002816"
     CDS             15554..16369
                     /locus_tag="PC466_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HDF2770181.1"
                     /translation="MKVFKKLLSLGLVLGLTLSLVGCSGGGEKTKLEQIKDNGKLVVG
                     TSAEFPPFEFHKVVDGKDSIKGFDIMLAEEFAKELGVKVEIKDMSFDGLIGALNADQV
                     DIVLAGMSPTPEREKSVDFSELYYLSRNAVIVKDADIDKVKTEDDLKKLRVGVQAGSI
                     QEEYVVNTLKMTTTKSLKAIPDLITELKNGNIDAVVTNEAVSLINVKKYDGIKMANTE
                     VGKDVTEGMAAAIKKSDNNKDFIELLNKKIKELQDGKKIEEFLNEASTEAASN"
     gene            16397..17074
                     /locus_tag="PC466_002817"
     CDS             16397..17074
                     /locus_tag="PC466_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HDF2770182.1"
                     /translation="MSLDFSFLSRFGTSFLEGTGVTVSISLVALCFGFIIGIIICMAK
                     ISKSKVLRAISSIYIEVLRGTPLLVQIYIVWFGLPQLGIRFPMLFGIPSEFIASAFAL
                     SVNSGAYVAEILRSGIQSVDNGQMEASRSLGLNYWSTMRYIIIPQAIKNILPSLANEF
                     ITLVKESSIISVIGVVEIMRTADIVKNAAFRALEPLIVAAAIYFVITFTLSRLVGLLE
                     KKLSVSN"
     gene            17133..17855
                     /locus_tag="PC466_002818"
     CDS             17133..17855
                     /locus_tag="PC466_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004398740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HDF2770183.1"
                     /translation="MITIKNLSKSFGDLNVLKNIDLEIAKGEIMVIVGPSGSGKSTLL
                     RCMNLLEIPTGGEIIFEGKNLVDKKTNIDEVRQNIGMVFQNFNLFPHKTILDNITLAP
                     IKLKKMTKEEAEKKAEILLSRVGLLDKKDSYPSQLSGGQKQRIAIARALAMEPDMMLF
                     DEPTSALDPEMVNEVLDVIKELAKEGMTMAIVTHEMGFAKEVADRVIFIDGGSILEDN
                     TPEEVFGNPKHERTKAFLAKVL"
BASE COUNT         7178 a         1929 c         3242 g         5885 t
ORIGIN      
        1 tgaataaaaa acgattgcgt caaaaataaa aaacaattaa atgtaagaat aattatgtca
       61 aaaatataaa ataaattaaa agaaaaagat tatactgaag gaaaaagatt tgaaataggg
      121 gtgaacttta catattatag ttcaccctta tacaaaaata taaaatataa tttattatag
      181 gaaaatttaa aaaaatcagt ctatttaatt tatactgatg tattgtagga ttttacaaac
      241 aaactgttat ataacttttt ttatctccaa ttttgatttt aagatatcta agaatttata
      301 acaatcttct ggatatattt ctcccatatt tgcaacttgg aatatgttag catctaggaa
      361 tttgcctttt cctggataga caacatagcc actttccctt tctaggccta atataaactc
      421 atttacattg atttctttag gtagaaatac agatgttact gtattagaca tatacttatc
      481 tggaagtaaa aatgttagcc ccaattcttc catgccattc cttaaaatag cagaacattc
      541 tttgtatctt tctattttac tgtcatcttc caaaaactca gttaaagctt cattaagggc
      601 aaatattaaa gtaacattag gtgtatttgg tgtttgagaa gatgatttag caactttata
      661 gtgtttataa agattaagat atacattctt acattgattt tctttaatat tttgtaaaat
      721 actctcttta gcacaaaggt atgcagaacc tggaaatgct ccaagagctt taccaccaac
      781 acctgttatt atatctatat taaactcttc tacatcaata tattcacctg ctgaggcact
      841 tattgcatct acaaaaaata ttttgttata cttcttagca agttttccta gttcagggac
      901 tggatttatc attcctgaac tagtttcatg gaacaccata gcaattactt ttatatcaga
      961 attttcaatt atatattttt ctaaaatgtc caggtctggg tattctgccc attcaaaatt
     1021 aggcttatat gtttttacat tataagtaaa taatatttct tctagccttt ctccaaaaac
     1081 accattacta actagcagaa ctgcatcttc tttgtcaaag atagaagata gtacacattc
     1141 atttacagat gttccagagc cagatacaat taatgagtag taattagaag ttgcattata
     1201 tagtttattg attttttgtt gtgtatcttt gaataaatcc ataaactcgt ttcctctatg
     1261 gcatatatca tagtgaagaa gtgaatttct gactttatct gtaaccatta ctggtccagg
     1321 actgaataga tatgtttttt tcattgtaaa gcctccttaa aaagttaaat ttaaattttc
     1381 gaatgactga ctatgtgtaa atattaaaat attgtgtgtt attttaacta gattatagaa
     1441 taaaataatg aatattgcaa taatatttca ataaaaatac ttttttaatc accataatta
     1501 aaaataacaa aaaatattgt aatgaatatt gcataaatcc acatgatgat ataaaatata
     1561 aataacttga atagattata tattcaaaaa ataaaaaaga atttattaat tctgaaaata
     1621 aagggggaca ttttaagtga aatatgtatt agcaattgac caaggaacaa caggaacaag
     1681 agcagtattg ataaacgaaa aatcagagtt tgtttttagc gattatatgg aacatactca
     1741 aatatatcca caatctggat atgttgaaca tgaccctata gaaatttgga ataatacaaa
     1801 aactgtgagt aataatgtat tacaacaggc ttttgaaagt ggaatcaatg aaagtgatat
     1861 aaaaggaatt ggtatagata atcaaggtga aacagtaatg ttatgggata aaaatacagg
     1921 taaaccactt tacaatgcta tcgtatggca gtgtaggaga acttatgatt atgtggaaaa
     1981 tttaaagaat ataccaggtt tagaaaataa gataatagat aagactgggt taattataga
     2041 cccatatttc tcaggtacaa aaattaaatg ggtaatagat aatgtaaaag gtgtaaaaga
     2101 aaaaattaaa aatggagaag tacttgcagg aacattggat agttggttaa tatggaaaat
     2161 gacaggagga aaatcttttt taactgatgt atctacagca gcaagaacaa tgctttttaa
     2221 tataagagat atggattggg atagagagtt gcttgacatt ataggagtgc ctagaagtat
     2281 tttagcagat ataatgccta ctagtggtga ttttggaact acagataagg aggcattttg
     2341 tggggtttct ataaaaatta ctgcttcaat ggtagaccaa ccagcagctt tatttggcaa
     2401 tggatgtttt gaaccaggaa tggttaaaaa tacttatggt acaggatgtt tcttatatat
     2461 gaatataggt gaggagttaa atatagcagg taatggtatt ttgacaacag ttgcttggaa
     2521 gataggagat aaagttacat atgcttatga tggtggagtg tatatagcag gtgctgcaat
     2581 acaatggctt agagatggaa ttggagttat aaaaaattat tcagaaactg atgacatggc
     2641 aaattccata tcaagtactg gaggggtata ttttgtacca gcatttgcag gtatagcagc
     2701 accttattgg gaccaatatg ctagaggcac aatggttggg ataacaggaa gtactaaaaa
     2761 agaacatata gtaagggcta ctcttgagtc tgttgcactt caagtcaagg atgttgttga
     2821 ttccatgaat ttggcttcag ggaaagaaat aaaaatgttg agagtagatg gtggaattac
     2881 taaaaataac tttacaatgc aatttcaatc tgacatatta gatataccaa ttgaaattgc
     2941 agaaaatcct gaaacgacag tacttggtgt agggtatatg gcagggcttt cctgtggtgt
     3001 ttggaacagt attgatgaaa ttagaagtga atttacaata agcaaaaaat atattccaaa
     3061 tatgactaag caaaaaagag aagaaatatt acttggatgg aatcaagcag taaaaagagc
     3121 tatgaattgg gaaaacgata ccaaaaaggt gtgtgctaat taagttacaa tagagtattt
     3181 tacatgtata ggaggaatta aaaatgccct ttgataaaat tatattatac ataatggctg
     3241 tgggagtgct tttaggagcg ttagatagaa taattggaaa taaatttgga cttggagagc
     3301 agtttgaaga agggtttaat tcaatgggtc cattggcttt aggaatggtt ggtatagttt
     3361 gtttagctcc agtaatttca gatgtactag gtcctataat aataccaata ttcaatctct
     3421 gtggagctga cccatctatg tttgcaacta ttttagcgaa tgatatggga gggtatccat
     3481 tggctatgga acttgcacac aataaagagg caggaatgct tgcaggatta gtcgtgtcat
     3541 ccatgcttgg atgtacatta gtattttcaa ttccagtagg actaggtctt atagaatatg
     3601 aagacagacc attctttgca aaagggttac tgataggctt gataacaata ccttttggag
     3661 gtattatagg aggattaata gcaggattta acttatcaat ggtaattata aatatgatac
     3721 cagtgataat attggcagta atattggcag taggtttaaa atttaattct acacttatga
     3781 taaatgggtc attagttttt ggaaaattta tatctatatt gataacgata ggtttgggag
     3841 cagcagcatt tcaagaaata acaggtatag tacttataaa aggcatgaca cctataagag
     3901 aaggtattca agtaattgga agtattgcaa tagtgttatt aggtactttt ccaatattac
     3961 atttattagt taaagttctt aataaaccac ttacaatagt gggtggaaaa ttaggtatgg
     4021 atgccactag tgcagcagga ttagttttta ctttagccaa tagtattcca gtatataaaa
     4081 tgatgaaaga tatgagtcca aaggggaaag tagtaaatac tgcttggctg gtttgtgcta
     4141 cagcagcttt gggggaccat ttaggattta cagcaggagt agttccagag atgattacac
     4201 ctgttgtaat tggaaaattg gttggaggag tattggcaat tgcacttgct atacttatga
     4261 caaaagattt aactttggaa gaagaacaaa gtattaaaat gaagaaagat gcagtgtaga
     4321 ataaacaata cttaagtcaa atttaagtta ttttaaagta ggagtttaaa taactaaaaa
     4381 taaattaaaa agacagacaa ttaaaaaata atcgaataac caaaactgat aaattaaata
     4441 aaatggcaat caaataacta aaaatgataa gctaactgaa agtagttaca taattaaaat
     4501 ataaagtata gtttagacat aagtggagct aaataaataa ttatttggct ccttaatttt
     4561 aatttattac atcaaggaac taaaaatcaa tcatacaagc taattatcag ctatgactaa
     4621 aggtattcct ttttgagaaa actctattat tatattatgg tctatactag cagaggtaat
     4681 aatagtatct atgtgttcta taggagctac tgatgcaaat gaatttatac caaacttagg
     4741 aggttcgaca actactatag attttctaga cctttcaatc attttttttc taaccagtgc
     4801 ttcttctaag tgatagtcag agattccatt ttcaagagtg atacctccag cacctaaaat
     4861 agctttatca acattaaatt gttcaatagc tgagagtgta agtggaccag aaaaagaacc
     4921 ttcagtttct ctaagatagc caccaagcac atatactttt atattagtat tcataagttc
     4981 atttgcaact aaaattgagt tggttattac agttagattc tttttatctt tcaaattttt
     5041 tgaaacttca agtacagtag ttccagtatc cataaaaata gtatcatttg tatttataaa
     5101 ctcactacat ttaatagcaa tctgtttttt atcgtttgag tttatttttt ttcttttaac
     5161 atagttaagt tctacgctac ttgctataac tggtatagca ccaccataaa ctctttttaa
     5221 aagaccgata ctttccatat gggctaaatc tcttcgtgca gtttctattg atatatcaaa
     5281 catttgaact atgtcattta ttttaattat attatctgat ttgagaatac ttaaaatctt
     5341 ctcgtatctt tcctgtggta acataaaata tcctccttgg actagtatta ttttagtttt
     5401 ggcataactt acaattaagt cagagtttag gtatatttgt taatgtatgt atatttatca
     5461 aataatatta taagtgttat gcaagataat tttaccatat ttaaaactta catttaagca
     5521 aaaaagtaaa aatagatgtt taataattca aaataactca aattttataa aacaattgac
     5581 taaaatatga ttttattata taatttacta gtatagagat atggagaagt actcaagtgg
     5641 ctcaagagga tcccctgcta agggattagg ctgggtaacc ggtgcgaggg ttcgaatccc
     5701 tccttctccg ccaattgtta aaggctattt ttattaaaga tagtcttttt ataatgtcat
     5761 aaatgattag atatgtataa ttaaagaaag gagggaatag atgacaactt taattttttt
     5821 catagtgggg atagcatctt tggtagttgc ttttgttatt gatgggggac atattggagt
     5881 attatttgta ttttcatcag cacttgttgt gtttggtgga actataggcg ctgttggagc
     5941 ttcgactcca ttccctgtgt ttaaaaagtc tataaagata atgttattag cttttaaaaa
     6001 taaaaagcct aataacatag aaaatataat ctatttcaaa gaaattgcaa caaaggctag
     6061 gaaagagggg cttcttagtg ttgacaaaga aataagtgag aatgatgaat tagacccttt
     6121 tattagaaaa gggcttgaac ttatggtaga tggggtggat gcagttacta taagaaatat
     6181 attggaatca cagatacaga taacatcaaa acgacataaa gaaggaatag caatttttga
     6241 ttcagcaggt ggatatgcac ctacactggg gataataggt acagttatgg gattagtaca
     6301 tattttaggt aatctttcaa gtaatccaga tgcattagga cctcaaattt ctgttgcatt
     6361 tttggctact ttgtatggtg ttggttctgc caatttaata tggttaccaa tagcatcaaa
     6421 acttaaggct ataaatcaac aggaaataag tgaaagactt ttggtgatag aagcaatatt
     6481 atccatactt gagggtgata attctaattt aatgacagaa aaattaaaaa tatttttaaa
     6541 ttcaaaagaa ctaattgaac ttgaagaaat tggtggtaga gctgaataat ataaaaggat
     6601 ggaatgttta tgttgtatga tgaagatgaa aaagaagaaa acaatgagcg atggctttta
     6661 acttattcag acctcataac attacttatg attttctttg taataatgta ttctatgagt
     6721 aatgttgatg cggagaaata taaacaatta tctcaatctc taaattctgc ttttggtggt
     6781 tcttctggag ttattgaagg tggtaatagc aaaatagaac cagtagttga accaggaagt
     6841 aatgatttag atagtttaca aaatgctaag tttaaaaaag ttggtgaaga aatccagaag
     6901 tatttaaatg aaaatggtat ggctaattca gtatcattaa gagttcaaga tagaggatta
     6961 gtaataagcc ttaaagatac aatactattt gatacaggaa aagcagttgt aaaggataat
     7021 tctagagata agattattca aataggtaag atgttaaatg aaatgaatag ttacatgaga
     7081 gtagaaggtc atacagacaa tatgtctata aaaaattcag agtttaagtc aaattgggat
     7141 ttatcagtta tgagagcaac caatgttgtt caacttctta ttgacaatgc aggtatagca
     7201 ccagataaat tatctgctgt aggatatggt gagtttagac caatagcaga aaattcatct
     7261 gaagaaggta ggtcaaaaaa tagaagagtt gatatagttt tagttgatag taaatatgat
     7321 aatgtagaaa atgtttcaaa ggataaatag ttaaattagc tgtctcaata cagaattaat
     7381 tctaaaggag atggcttttt tatgcgaaaa ttaaaaatag atacatagta agttaccttt
     7441 ttgtaggaat atatggtatc ttaaatatat aatatttaaa taatatataa gctcaattaa
     7501 aaaaatttta tagaggatgg gaaataaatg gggaataaaa ataaaaatac gaaatataaa
     7561 gataaaacaa gagaaagata taataaaaaa gttgagaatt taaataaaga aaaattaaat
     7621 aaagataata aacagtctaa gaaggtagat aagattgatg atattattaa taaatctagt
     7681 attgtattat gtgtacttct agtggtgttt tcattacttt acttatttaa attggttcaa
     7741 cttaatataa taatgatact tttagtaatt acagtagcta ttcaacaagg attggtgtca
     7801 tttggtgcat ttagaaataa aaattatgta aaagctttat tttctatatt tgtaatagta
     7861 tgtttcttaa ttgcttttaa atatgttgta aatcctgttt aaatatatca ataaacgttc
     7921 tataattaat ataaatagtg aagttacagt tttaatgcta ttataaattt tataatttga
     7981 aggagtagat tttatgaata ggtgtaagtt tgcaaaatta attatcacat caatgattgt
     8041 tttattactt acaggatgta gtttaaaaaa ggaagataat tataagttag acccagaaaa
     8101 tccgacatca atacaaattt ggcattatta taatggacag caaaaaatgg cttttgataa
     8161 gcttgttaag gaatttaatg acactatagg tgctgaaaaa ggaattattg ttgaagcgtt
     8221 tagtcaaggt aatgtagttg atttatcaga gaaagtttta gattctgcaa ataaaaaagt
     8281 tggctctgaa gatgtgccaa atatatttgc agcatactca gatactgcat atgaaatgga
     8341 taaattaggg ttactagtag atatggataa gtacataagt aaagaagaat taaatgaata
     8401 catagacgaa tatgtagaag aaggcagaat aaattctaag gatgagttta aacttttccc
     8461 aattgcaaaa tcaactgaaa ttttgatgtt aaataaaact gattgggata aatttgcaaa
     8521 agctacaaat tcaaatataa atgatataaa aacaattgaa ggattagtag agacatcaaa
     8581 aaaatattat gaatggacag atagtttaac gaaagagcct aatgatggta aagcattttt
     8641 tgggagagat gctttagcaa attatattat tataggaagt aaacaactag gagtagaaat
     8701 tttttctgtt aaagatggta aagttacact aaatattgaa gaaaaagtta tgaaaaagct
     8761 atgggataat ttctatgtac catatataaa tggatatttt gcttcttatg gtaagtttcg
     8821 ttctgatgat gcaaaaacag gtgatatatt agctcttgta ggctctagtt caggagcagc
     8881 atactttcca gatagagtaa tgctaaatga taatgagagt tataatattg aaacatctgt
     8941 ttttcaagca ccacgtttta aaggagaagg aaaatatgct gtacaacaag gtgcaggaat
     9001 ggctgtaaca aaatctacta aagaagaaga atatgcatca gtagaatttt taaaatggtt
     9061 tacagataaa gagcctaata taaaattctc tattgcttct ggatatttac cagtaaagaa
     9121 aaaaacgaat gatttgaatg ttataaaaga agttatgaag aaagataatt tgagtttatc
     9181 tgataaagtt gaaggttcaa tagcctcatc tattgaacaa attaacagtt gtaatttata
     9241 cactaataaa gcatttgatg gtggaactaa agctagacaa atacttgaat attcaatgct
     9301 tgataaagct aaagaagatt caaataaaat aaatgaattg gtaaaaagtg gaacttctaa
     9361 gaaggatgcg gtagcacaat ttaataatga taagaatttt gaaacttggt ttgaaagttt
     9421 taaggctgag cttgaaaatg ctataaaaaa atagatgaat tggcagttag tgtgtagaca
     9481 agcacaaagg tataggtgga ataagtatgg aaaacaatct aagaaaaaac aattcaataa
     9541 tgaaaaagat gatatttccc ctaattattg ttatgctaat tcaaacaagt ttattttgtg
     9601 ccacaatttt atggggagga actattaaga aattaaatga taattcgttt gacatcttaa
     9661 atgaaagagt aattaatcgt aaaaattata tacaaaatga aatgttacaa agatggtcaa
     9721 atacaagtga aacggaagct acaattaatt cctctgtaaa aaaaatatta aatgaaaaaa
     9781 atgccttaat tgaggatgta ggcaacaatg aagaaattaa caaagatatt ataaaaagca
     9841 tatcaaatga tttaatatat cttttgagaa aaaactctgt tacaggagct tttataattc
     9901 taaatgacaa aaatattaac gataagccaa tagatagtaa aggtgaaata agtaggactg
     9961 gattgtatat aagggattta gaccctaagt ttaatccaaa tgataattct gatttgttaa
    10021 ttgagagagg ttcatcagat atagcaagaa gttttggaat atctatggac agttattggg
    10081 aacctaaatt ttcatttaaa agtgaaaatg agcaagaggg agatgatttt ttttataaac
    10141 catttagagc tgcaattgat aatccaaacg tatcaagttc taatttggga tactggggaa
    10201 gtaagttttt attgacaaat gcaggtgata ggcttatgac atatacagtt ccccttattt
    10261 atgaagatgg aactgtatat ggagtacttg gaatagattt aagtgtaaat tatttaagag
    10321 aattacttcc atactcagag ataaatggaa ataaaaaagg taattatatt ttaggtgtag
    10381 atagaaataa tgatatggcc tttgaaaatg taatttcaaa tggatactca ttaaaagaaa
    10441 aattttggga tggtttacat tctaatttag agcagaagga atcgtataaa aatatatata
    10501 agattaaaaa taaagataat gaatgtggta atggcaacat ttatgctagt gtacaatact
    10561 tagatttata taactccaat actccatttg aaaatgaacg ttgggctctt ttgggtatta
    10621 ttgaagaaaa aagtcttttg tcattttcaa aaaggataga gaaattagtt ataatatcta
    10681 tagcaatttc tttattaata ggtctaatag gtatttacat tgcatcaaga ttatttacaa
    10741 aaccaattgt tcttttagcc aacaaagtta gaaacagtaa tccatcaaaa ccagtaaatc
    10801 ttgataagat aaatatatct gaaatagatg aattatcttc agctatagag ttactcagtg
    10861 caaatgttgc agattcttca tcaaaattat cacagattat tgaaatggta gatatgccaa
    10921 tcggggcttt tgagttatac aaaaacgcag agaatgtttt ttgtacaaaa gataaaaaac
    10981 ttaagtggat aagaatgaat atctttgaag atgagctaaa ggttcttggt gttgttgttg
    11041 atgtcacaaa agaatttatt gagaaaagga agatagaata tgaaagagat tttgatattt
    11101 taacgaatct tttaaatagg agagcttttc attcacagat acaagaaaaa tttaagaata
    11161 aagatgaact taagatagca gcatttatta tgtgggattt agataatcta aaatatatta
    11221 atgatacata tggacatgat gctggtgatg aatatattag gtgtgctgca gacatactta
    11281 agaagtttat atcatggaat ggtatagtat ctagactttc aggtgatgag ttttatgtat
    11341 ttatatatgg atatgaaagt aaagatagta taagagatat tattaattct gttaagaaac
    11401 agatgaataa taccttatta aaacttcatg atggaacaga atttaaaata agggcatcag
    11461 caggaatttc ctggtaccct gatgattcaa ccaactatga tgaattaatg agatacgcag
    11521 attttgctat gtatcaaatt aaaaatacaa tcaaggggga agttagtgaa tttgatatta
    11581 atatatataa taaggattca ttcttattga gtaatagaga agaattaaac aagttaattg
    11641 atggtcaatt agttgagtat gcatttcagc ctattgtaga ttgtaaaggt aaagtatttg
    11701 catatgaggc acttatgaga cctaaaataa aaacttttag ttcaccaata gatgtaatta
    11761 gattagctcg ttcacagtct aaattatatc aaattgagcg tattacatgg tttaaagcac
    11821 ttaaatcatt taaaaaatac aaagaaaaat ttggcgattg caaactgttc ttaaattcta
    11881 ttcctaataa taatttatca aaagtagatt ttgaggaaat tgaagattta tatggtgaat
    11941 atttaaatag agtagtatta gaaataacag agaatgataa gattaatgaa gattttattg
    12001 agaaaaagaa agcatatata gaccattgga atatagaaat tgctttagat gactttggga
    12061 caggttacaa cggagatgct gtactattat atataatgcc agactatgta aagattgata
    12121 tgtctattgt aagaggtatt gataaagatg aaaacagaca gaaaatatta aaaaatctta
    12181 tctcatattc taacgaaaga aatattaaag tgatatcaga aggtgtagaa acaaaaggtg
    12241 aaatggaaac actgattaat cttggagtag attatatgca gggttactat attagtaaac
    12301 catcatttat acctgaagat ataagtgaca aaattaaaaa agagctcaag atatgtcatg
    12361 aaaataggaa tgatgtggtt taatagagga aaaattaaat ttatttttat gaacttttag
    12421 tttataatta aaaagaaaat aatataatta taaattaagg tggtggagct aataatcaca
    12481 acaaacatag atataagaaa gttaaatgaa aatcaattag aagcagttga acatatagat
    12541 gggccttgca tgatacttgc agggcctggt tcaggtaaga ccagagtaat tacatataga
    12601 atagccaata tggttgtaaa caaaaatata gcaccaacaa gaatcttggc aataagtttt
    12661 accaaggcat cttcaataga aatgaaaaat agagctttga atttaagtga tgatataaga
    12721 cttaataagg taacctatgg tacttttcac tctgtatttt ttaaaattct aagatacttt
    12781 gaaagataca atttagacag tatatttgat gaaaagtcaa agcgaatgac aatcaaggca
    12841 atcctaaaaa gtttaaatat agagaatgct gatgatgatg agaatatagg acaagttata
    12901 aatgaaatct cctatgtaaa aaatgaactt atggataaaa atgaatttaa ttcagaagta
    12961 ttaacaaaag atgagttttt aaaagtatac aacttatacg aagaacaaaa atctaaagtt
    13021 aacaaaatag attttgatga tatgcttata agaacttatt atttactttt gaacaataag
    13081 tctgcactag aaatggttag aaatgtgtat aaatatatat tgatagatga atttcaagat
    13141 ataaataaag tacagtttga agttttaaag ttaatttgta gcccattaaa caatatattt
    13201 gcagttggag atgaagacca aagtatatat ggatttagag gtgctagacc agattttttg
    13261 cttgaatttg aacaatactt taataatact aaaaaaataa tattagatat aaattatagg
    13321 tctaaaagtg agatagtgta tactgcaaat agacttatcg acaaaaataa aaatagatat
    13381 gaaaaagtca ttaagtgtag tcagggggat ggaggaagtg ttacctacat ttctccacat
    13441 gattcagagg aagaagcctt atatattgcc aaggaaataa ttgacgaaat acaaaaagat
    13501 tatgtagagt attcagattt tgcagtaatt tatagaacaa atatacagtc aagagcatta
    13561 gtagatgtat ttatggatat gaggattcca tttgtagtaa aagactcagt aattacaata
    13621 tatgaccatt gggcaagtca agatatacta gcttatttaa gaataggtat taatccaaaa
    13681 tcaaataaag attggttgag aattataaac aagcctttta gatatatatc caaagacagt
    13741 ataaatatgg ttaaggatga aaaagacttt ataacagcat taataaataa gtgtaatctt
    13801 catcctaaac aagttaaaac aataaatgat ttggaaatag atttaagtta tttaaatact
    13861 ttaaatccta aaaatgcaat atcttatatt agaactagtc ttgattatga tagatacgtt
    13921 ttagattatt gtagcaacag aaagataaaa actaatggac ttgtagagat attaaatgaa
    13981 cttgagagtt cagcaactaa ttttaatact gttacagagt ttttagagca tattgataga
    14041 gtaaagactg agttaacgga aaataacaag aataagcaga ctgagggtgt catatttaca
    14101 actatgcata gtgcaaaagg attagaattt agaaatgttt atattatagg tgtaaatgaa
    14161 ggaacaatac ctcatgaaaa atcatatgat atttgtaagg aagagaaaaa agaagaacaa
    14221 ttagaagaag aaagaagact tatgtatgtt gctattacaa gagctgaaga aaagttatgt
    14281 ataagctcta ctttaaataa gtatggtaag aaagttgata aatcattatt tattaatgat
    14341 ataaaatctc caacgaaaaa agaaattgac agtattggtg taggggataa ggtataccat
    14401 aaaaaatttc atgaaggaga aataattaaa aaagatggaa ttatgtttac aataaagttt
    14461 aaagatagag agcgaatctt ggatttgaaa acttgtttat tgaagaatat aatttatact
    14521 atttaattta gaatctaaat ttagatagaa atataatgta ttatttatta tgtgcaagac
    14581 aaatagatat gtgtaaaatg tattatttaa cttattagaa aaagaaataa ggatttaata
    14641 tattatttat agttgtttag aaaaagcaac aatgtggaaa atattattta gtattattaa
    14701 agaaaagcaa caatgtgaaa gatattattt agtgtaattt aagaaaaagc aacaatgtga
    14761 aagatattat ttagtattat taaagaaaga gcaacagtgt gaaagatact atttagtatt
    14821 attaaagaaa aagcaacagt gtgaaagata ttatttagtg taatttaaga aaagcaacaa
    14881 tgtgaaagat attatttagt attgtttaag aaaaagcaac aatgtgaaag atattattta
    14941 gtattattta agaaatagct aaaaatatga aatatactat ttataattac aaaaataata
    15001 tcaataaata taaacagtag tatttagata atttacaagt aaaaattatt aaaaaaataa
    15061 aaaacttatt gacaaaaata ttataaggaa gtacaattgt attaacaatt taaggaaaca
    15121 aatccaatga tagagaaagt agcatatatg gatttacagc gagttagggg ttggtgtaag
    15181 cctagcaatg aagtctatgt gaagagagct ctggaggaga ttatcagaaa ctttagtatg
    15241 ataattggtt tacccgcctt aagggattga gaggataagt acttacttat caaaaagagt
    15301 ggtaacgcgg atataattcg tctcttagct gtaaagctaa gggacttttt tgatttaaaa
    15361 ataaaaatat ccatacagct taaatgctaa cagtcacaaa ttttgaaagt aatataagta
    15421 tttatcaata agagtggtaa cgcggtaaag tcgtctctta gtcattaaag actgagagac
    15481 tttttttgta actcgaaaca tttaagtatt aaaatctgag ggaaattata attaaaagag
    15541 aggggtagtt aaaatgaaag tatttaaaaa attattaagt ttaggattag tattaggatt
    15601 gacattatcg ctagtaggat gtagtggtgg aggagaaaaa acaaagttag aacaaataaa
    15661 agacaatgga aaattagttg ttggtactag tgcagaattt cctccatttg aatttcataa
    15721 ggtagtagat ggaaaagatt caataaaagg attcgatata atgttggctg aagaatttgc
    15781 aaaagagctt ggtgtaaagg ttgaaattaa ggatatgtca tttgatggat taataggtgc
    15841 tttaaatgca gaccaagttg atattgttct tgcaggtatg tctccaacac cagagagaga
    15901 aaagagtgtt gatttttcag aattatatta tttaagtaga aatgcagtta tagttaaaga
    15961 tgcagatata gacaaagtaa aaactgaaga tgatttaaag aaacttagag ttggagttca
    16021 agcaggaagt atccaagaag aatatgtagt taacacttta aaaatgacaa ctacaaaatc
    16081 tttaaaagca atacctgatt taattacaga attaaaaaat ggaaacatag atgcagttgt
    16141 tactaatgaa gcagtttctt taataaatgt taaaaaatat gatggaataa aaatggcaaa
    16201 tactgaagtt ggtaaagatg taacagaagg tatggcagca gcaatcaaaa aatctgacaa
    16261 taacaaagat tttatagaat tattaaacaa aaagataaaa gaattacaag atggtaagaa
    16321 gatagaagaa tttttaaatg aagcatctac tgaagctgct tcaaattagt aagaaagtta
    16381 tgtgggagat gaaattatga gtttagattt tagtttttta agtagatttg ggacttcttt
    16441 tttggaagga acaggtgtga cagtatcaat ttctcttgtg gcattatgct ttggatttat
    16501 aataggtata attatctgta tggcaaaaat atcaaagagc aaagtattaa gagcaatatc
    16561 atcaatctat attgaggttt taagagggac accattatta gtacagatat atatagtatg
    16621 gtttggttta cctcaattag gaataagatt ccctatgttg tttggtatac caagtgaatt
    16681 tatagctagt gcatttgcat tatcagtaaa ctctggtgca tacgtggcag agatacttag
    16741 atcaggtata caatcagttg ataatggaca aatggaagca agtagatcat taggattaaa
    16801 ttattggtca actatgagat atataataat acctcaagct ataaaaaata tattaccttc
    16861 attagcaaat gagtttatta cacttgtaaa agaatcttca ataatatctg taataggagt
    16921 tgttgagata atgcgtactg ctgatatagt aaaaaatgca gcatttagag cattagagcc
    16981 attaatagta gcagcagcaa tttactttgt tataacattt actctatcaa gattagttgg
    17041 attattagaa aagaaactat ctgtgtctaa ctagatgaga gcatgtttag catttaggga
    17101 aaacatagaa tagtaaaaag gaaagtgata atatgattac aataaaaaat ttaagtaaat
    17161 cttttggaga tttaaatgta ttaaaaaata tagacttaga aatcgctaaa ggcgaaataa
    17221 tggttatagt aggtccaagt ggttctggta aaagtacact tcttagatgt atgaatttac
    17281 tagaaatacc tacaggtgga gaaataatat ttgaaggaaa aaatttggtc gataaaaaaa
    17341 ctaatattga tgaggttaga caaaatatag gtatggtgtt tcaaaacttt aatttattcc
    17401 cacataagac tattttagat aatataacat tagcaccaat taaattaaaa aagatgacta
    17461 aggaagaagc agaaaaaaaa gcagaaattt tgttgagtag agttggtctt ttagataaaa
    17521 aagattcata tccatcacaa ttatctggag gacaaaagca aagaatagca atagctagag
    17581 cacttgctat ggaaccagat atgatgttgt ttgatgagcc aacatctgct cttgacccag
    17641 aaatggtaaa cgaagttttg gatgttataa aagaacttgc taaagaaggt atgacaatgg
    17701 caattgtaac tcatgagatg ggatttgcta aggaagttgc agatagagtt atttttatag
    17761 atggaggaag tatacttgaa gataatactc cagaagaagt tttcggaaat ccaaaacatg
    17821 aaagaacaaa agcattttta gcaaaagtgc tataatatat aaaaaggatg ttattgatat
    17881 tagaaattca atacatcctt ttttagtgat ggttaatatt aattttaaaa ttaaagttat
    17941 attaatatta actttatttt tacgattttt tgcagaaaaa aaaagagctc ggggtaagct
    18001 ctttttttcc accgaattaa tttccgttac taatccgatt tttaataaat ataaaatata
    18061 tccttatgaa agggtattgg gaatagatat attaactaac tagggttacc agggggataa
    18121 ccttaattta ttataacaaa atgcgacaca aaaatcaata ttttttttga aataaattat
    18181 aaaagttatt tttataacaa gtaagcttat aaatttaact tttatagtaa aaat
//
LOCUS       DAMJYN010000075        17732 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.078, whole genome shotgun sequence.
ACCESSION   DAMJYN010000075 DAMJYN010000000
VERSION     DAMJYN010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17732)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17732)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17732
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.078"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(<1..108)
                     /locus_tag="PC466_002819"
     CDS             complement(<1..108)
                     /locus_tag="PC466_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HDF2770184.1"
                     /translation="MKSLVLYSSLTGNTKKIAYAIYDEIQEEKDIKDVNE"
     gene            complement(196..1290)
                     /locus_tag="PC466_002820"
     CDS             complement(196..1290)
                     /locus_tag="PC466_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH:flavin oxidoreductase"
                     /protein_id="HDF2770185.1"
                     /translation="MYCNLLKPIKIGNLELKNRVSFAPTSMGLKLEEKIKKFSDIAKS
                     GVALITLGDVSIRPSFHKVAISLSDEDGVIKYKKIVDEIHNSGAKVSAQLFCSDYDVN
                     LIKDTMKMGITSHDEIKKIMNDGVKDYITNMPKEEIKNIINLFKVTALNAKKAGFDMI
                     QIHGDRLVGSFSSSIFNNRNDEYGGTCDNRSRFASEIISSIRDEVKDIPIDYKFAIRQ
                     ENPHYGNAGVLLSEVEYFVKKFESLGVNSFHVTLANHSKLEDTIPTNNHPYFKDEGCF
                     LYLADEVKKHTNLPVCGVGKLSSPDFIESIISNNRVDMVSMSRQLLADSNWLQKVKDG
                     RVDEIKKCCYCNKKCADALQTRSQFGCILD"
     gene            complement(1292..1738)
                     /locus_tag="PC466_002821"
     CDS             complement(1292..1738)
                     /locus_tag="PC466_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HDF2770186.1"
                     /translation="MDFKNLQYESLSYIICNLQKNFKLYCEKCLKPYKLTNGLYFYLI
                     YINKNRNCSLNDVSTEFEVDKAHTTRTISRLEQDGYIEKIQNPNDSRAFQLRVTDKGE
                     EVLGDIKNIFSKWDNHIKKEFSDTEYKELVKNLHVVKDIKTAVEEG"
     gene            2044..3234
                     /locus_tag="PC466_002822"
     CDS             2044..3234
                     /locus_tag="PC466_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HDF2770187.1"
                     /translation="MISNKMQTLVANSSVIRAMFEEGKKLSDIYGEENVFDFSIGNPS
                     VEPPETIKAVINDILNEESPNLVHGYMNNSGYEDVRDAIAEHINKKDGLNLTRENLIM
                     TCGAAGGLNIILKTLLNPGDEVIAFAPYFGEYKNYTENYDGKLIEVPTNIETFEPDLD
                     ALKNAITPKTRALIINTPNNPTGVIYSEELLKNLGELLDSKQKEFNTSIYLISDEPYR
                     EIIYDGAKVPCVLKYYRNSFIGYSYSKSLSLPGERIGYIVANGQMDDFDDVMSSLNVA
                     NRILGFVNAPSLFQRVIARSLDAEVDVNIYKKNFDLLYNSLIDMGYSCVKPNGTFYLF
                     PKAPIEDDKKFCNDAKQFNLLLVPGSSFGCPGHFRVSYCVSYDKVKSSLPAFEKLAKL
                     YNLK"
     gene            3404..4366
                     /locus_tag="PC466_002823"
     CDS             3404..4366
                     /locus_tag="PC466_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HDF2770188.1"
                     /translation="MKKGYVYIILTTLFFSSMEISLKTVTNDFNPLQITLSRFFVGGL
                     VLLPFAVKRLRALSLSITKSDLKYFAFLGFMCVVVSMSLYQLAVLNTKASVVAVLFSC
                     NPVFVMLLAYLILKEKIYRHNVISLILEVLGIIVIINPLHTKLTLSGIFLTLSSAIIF
                     SMYTVFGKRKTLKFGGIVVTCFSFIFGSLEMLILVLLTKINFIADILNKNKLHIFANI
                     PIFSGYTLHNMPIMIYVFVFVTGVGYALYFMAMEATSTSLTSLVFFFKPVLSPILALL
                     ILKEIIPINMVIGILLIVIGSIISIIPTIITQMHNKHVEALYKE"
     gene            complement(4484..5146)
                     /gene="zmp1"
                     /locus_tag="PC466_002824"
     CDS             complement(4484..5146)
                     /gene="zmp1"
                     /locus_tag="PC466_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease Zmp1"
                     /protein_id="HDF2770189.1"
                     /translation="MRPSKKLLIAIISIFLISSVPVSAHAYSTTIQQNKDTLSQIVVF
                     PTGNYNKNEANAMVNRLANIDGKYLNVLKQDNLKIKLLSGKLTDEKEYAYLKGVVPKG
                     WEGTGKTWDDVPGLGGSTVALRIGFSNKGKGHDAINLELHETAHAIDHIVLNDISKSA
                     QFKQIFAKEGRSLGNVNYLGVYPEEFFAEAFAYYYLNQDTNSKLKSACPQTYSFLQNL
                     AK"
     regulatory      complement(5246..5331)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            complement(5517..8471)
                     /locus_tag="PC466_002825"
     CDS             complement(5517..8471)
                     /locus_tag="PC466_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021362860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SrtB-anchored collagen-binding adhesin"
                     /protein_id="HDF2770190.1"
                     /translation="MKKGNKKALLISLIMILSMVVSTIYPTVSYASELGENSQIQSGS
                     TNSSTGEEKESDNKKPEQTPEKDKATDNKKPEQTPEEDNSTDNKKPEQTSEEDKSTDN
                     KKPEQTPEGEKPIDNKKPEQTPEGEKSIDNKKPEQIPEEDKSTDNKKSEQALEDEKPL
                     DNKNTEKTPEEDNLLEDENLLKVLEEELNEDYGFVVKINNNTIETESMKKISFNLTYT
                     PTSKGIQAGDSITFKVPDVFNKVNLDYTSECFDKTESNGEYTLTFRELPNGQSVMQGK
                     IGLEAYVKKVDEDTNAKIHIETTGKIESGSGDIDVEIKPGDKTDVPDAKGTLKKLVEG
                     RKSTTVFMPVKNKDINYSIQVNEKQEELKDIILYDELPEGLTLINGSVSVVTSDGKEV
                     SDFNIEQSKNSISVNFGNIDKSYTVKYKARISDKNAKHGNKYKNVARIESDGKKIQED
                     DATVSIFDRGDNYLLTKGHSGATNITQVGQVINYQISINDDKSPISNVVITDNIPEGM
                     RLTTSGEDGHDFRVVEVPMNGSWTPWSKEKIANNISYKVEEKRNESGQVDKVITGFTI
                     NLSKEEVESKFFIAYTLKVISIEDSYINRAVLDANNSEIDKNDEINFKKNSGLISAKK
                     EVDKKVLNSSDNQIVKYKINMSTYGVYDAGQVNLLDEVNPSLKISNIKYSDNLELKKE
                     AGDGKNTIRLVNKYEFKQIKEGEPVQSWVTFDADFTNVKVGETIQNVAQINGSSPPGV
                     ETTKQGYAFEAKKVDALDKNVLSGAKFNLEDAFGNIVVKDLVSDEDGVIQSSVKKPGI
                     YYLVEVMAPSGYEKLKDKIKVEIGNKDIGRIVDIGNIENIRQENPPVNPPVPPNTDEP
                     IVNPPVPPSTDKPRKPSNPSDTEDTIVINPPVPPSEDIINPPIPEILNPPVPPSEEVI
                     ETPVKQIVPIPEVVKPSVSEEKNNKAKDDTLVNPPVPPKTGDSTTIIGEILLVIGAIV
                     GLVVLRRNKNTN"
     regulatory      complement(8584..8669)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            complement(8795..9973)
                     /locus_tag="PC466_002826"
     CDS             complement(8795..9973)
                     /locus_tag="PC466_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HDF2770191.1"
                     /translation="MFSKILVKTFIRDSENVQNTDVRNKYGYVAGVVGILSNLLLFVI
                     KVFIGMFTSSIAIMADAFNNLSDMASSAITMIGFKLASKPADKEHPFGHGRIEYLSAL
                     IVAFMVMLVGLQFVKSSIERIVNPIPVKFEVIPLILLIVSIMIKIWLSRFNKFVGNKI
                     DSSALKAVSLDALGDVFTSSCVVISFIVARFTNFPIDGYVGIVVSLVILYAGFSLVKD
                     TINPLLGEAPDEEMVNSIIELLLSYKYIIGTHDLIIHNYGVGRCIASIHAEIPSNIDI
                     MEIHEIIDTAEREISEKLDIYLVIHMDPICLEDKEVMSAKKELEEILKKNSLVKSMHD
                     FRIVGKGSKKNLIFDIVVNPSEFSKDMSEDDLKEDITKLVKEINPEYNCVIVVDKDFI
                     "
     gene            10345..10530
                     /locus_tag="PC466_002827"
     CDS             10345..10530
                     /locus_tag="PC466_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HDF2770192.1"
                     /translation="MFFISDIYTKSPIKFDTPLQKEVYKILQKLDIDFERVDTDEAIT
                     MEDCVQINKKLNMKMVI"
     gene            complement(10595..13369)
                     /locus_tag="PC466_002828"
     CDS             complement(10595..13369)
                     /locus_tag="PC466_002828"
                     /EC_number="7.2.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-translocating P-type ATPase, PMCA-type"
                     /protein_id="HDF2770193.1"
                     /translation="MRYYNKPTKEVLKYLKTNPEIGLDDNEVEERKLRYGLNEFTIKE
                     GRTFWDELGESLTEPMILILIGAAVISSFVGELHDALGILGAIFIGISIGIITEGKSK
                     KAAQALSKLTENIEVKVLRNGKIIKISKNDLVPGDIVYIETGDMIPADGRLIQSINLK
                     LREDMLTGESDDVAKNADAVLDMEVVYSKTEIIEQDAIPAKQVNMVFGGTLVAYGRGI
                     MVVTHTGDKTEMGKIAQNLSNEDQQTPLQIKLGKLGAKIAGISGVIATLLCMFMIIQM
                     QRKGMLILDTSSILSFLQSLEPAKNAYMVCIALIVATVPEGLPTMINITLAITMQKMA
                     KINALVTKKEACETIGSVSVICSDKTGTLTQNKMMVEVAYVDGKYISGGEYQSNSYFE
                     QNCIVNSTADIEKEDNSFKYIGSATECALLLYHNDKNYNEMRKQTYLISQIPFSSEEK
                     KMSTLIRQEDSDILLSKGAPEVLLKKCSYVQQGKNIVPITPKVEKSILDEIKKLQIKS
                     MRTLGFAYKKMSNSKTEVAMTSEGELNLIGNSRSYMKEDNLVFSGFVGIVDPLREGVK
                     DSIDKAFNAGVDVKMLTGDNINTATAIGNELGLLNDGKKAVEATYIDVLTDKELREEI
                     KGISIVARSKPDTKMRIVSALQKSGEVVAVTGDGINDAPALSQADVGIAMGISGTEVS
                     KNAADIILTDDSFSTIVEGIKWGRGIYENFQRFIQFQLTVNIVAFIIAIISQLTGKDM
                     PFTTIQLLWVNIIMDGPPALALGLEPVRDYVLKRKPINRHSGIIARSMFVNIIINAIL
                     IITIVFTQSAFNILGATSEEQGTVIFSLFAFSALFNALNCREFGLNSTIPNFFKNKLA
                     LQIIVVTGIIQIIFTQVFQSFFNSVSLDFDMWIKIILFASTILLSNEFVKLILRTMKN
                     SRSMNSNSKN"
     gene            complement(13541..14797)
                     /locus_tag="PC466_002829"
     CDS             complement(13541..14797)
                     /locus_tag="PC466_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HDF2770194.1"
                     /translation="MLKTTKISDPELYKIVADELVRQEHNIEMIASESTAPTEVLELS
                     GCVFTNKTEEGYPGARFQAGSEEADKLETLAIKRAKEVFGAEHVNVQPYSGSTANYCV
                     YSSILKPNDTVLSMRLDQGGHLTHGSAVNFLHDIYKYEFYGVDPNTGRIDYDALEAKA
                     KECRPKLIIAGASSYPRLIDYERISKVAKEVGAYFMVDMAHVAGLVAAKVIPSPVPYA
                     DFVSSSTTKTFCGPRSGIVLCKAEHAKKLDKGVFPGTLGSIHLNTVAAKAFSLLYLST
                     DKFKKIMEQVVVNAQTLASELISHGFSIVSGGTDNHIVMVDLRSKNLTGKQFEKALEY
                     VGITVNKNVIPDDPQSPFVTSGVRIGLTSISQRGLKEKEVIQIAGIMNKVAENIDNKE
                     VLDECKAEAQELISKFPLYPEGYFED"
     gene            complement(14869..16371)
                     /locus_tag="PC466_002830"
     CDS             complement(14869..16371)
                     /locus_tag="PC466_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbgT family transporter"
                     /protein_id="HDF2770195.1"
                     /translation="MRALNVVERAGNKLPDPVTIFLLLCIIVVILSAVISNLGVEEIH
                     PSTKEVVKVVNLLEKEQIQSYLGSIVTNFQSFAPLGLVLVTMLGAGVAEKSGFMEVLM
                     KKGISKVPQKLVTVAIVFAGMLSHTAADVGFIILPPLAALVFLGIGRHPLVGMFAAFA
                     GVAGGFAANVMLSTTDVLLAGFTIPAAQMMDPSYQGNPAMNLYFAFISAIVLTFAGAF
                     VTEKFIAPRFTKYNDSTNDKDIQELSELENKGIKYALLSLLVVVVVIVALCIGDNAFM
                     KDPETGSILSSNAPLMKGIVPIITIIFLTPGLVYGKVSKKIKSDKDLVSMMGSSMSDM
                     GGYIVLAFIASQFINLFNLSNLGTILSITGAKLLAESGIPSYGLIIGFILLSGFINLF
                     VGSASAKWAILAPIFVPMFMLLDFNPALTQIAYRIGDASTNPISPLFPYFPVILAFAR
                     RYDKDIGIGTVISNMIPYSVVFTLIEIIILLLFMGIGIPLGPGGGISYVL"
     gene            complement(16462..17652)
                     /locus_tag="PC466_002831"
     CDS             complement(16462..17652)
                     /locus_tag="PC466_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2770196.1"
                     /translation="MHELILISEKYKEDILDFFTDIHMHPELSFKEFRTTKAIKDLLV
                     SLDIEILDLGMETGVVGLLKGKYDGPTVALRGDIDALPIYEEVDIEYKSRYDGIMHAC
                     GHDIHTSCLVGCAYVLSHIRDSLHGNVKFIFQPAEEVNKGAKMLVERGVMENPKVDAI
                     FGLHNHPDIPCGKIGVKLGGLMAAVDTIKIEVNGFGGHGGIPNRTIDPIVASSAIIMG
                     IQTIVSRNISPLESAVISIGTINGGTANNVISEKVDMTGTCRSFSNEVRKKISENLEN
                     IVCEIARGYQATAKLDYLFDLPAVINSKEMYTIACKSVCDLYSEDAIVDPIPSTGGED
                     FSIFMEKAPGFFYWLGVGNKEQDCIYQWHNPKFKADKNSILVGTNVLCQSVINYMDKL
                     KNKI"
BASE COUNT         5578 a         3076 c         2107 g         6971 t
ORIGIN      
        1 ttcatttaca tctttaatgt ctttttcttc ttgaatttca tcatatatag cataagcaat
       61 ctttttagta tttccagtta aacttgaata taaaactaaa cttttcatga tgtctcctcc
      121 tctttatcta aatacttatc taaatcacca aaaatatatt aaccttaaca aattatttat
      181 ttttataaag atattctaat ctagtataca tccaaactga gagcgtgttt gtaaagcatc
      241 tgcacacttc ttattacaat aacagcactt tttaatctca tctactcttc catcttttac
      301 tttctgtaac caattactat ctgctagtaa ttgtcttgac atagaaacca tatctactct
      361 attatttgaa ataatacttt ctataaaatc tgggctagac aattttccaa ccccacatac
      421 tggaagattt gtgtgtttct ttacttcatc agctaaatat aaaaaacagc cttcatcttt
      481 aaagtaagga tgattattgg ttggtatagt atcttctaat tttgaatgat ttgcaagtgt
      541 tacatgaaaa ctgtttacac ctagggattc aaatttttta acaaaatact caacttccga
      601 aagtaaaact cctgcatttc cataatgagg attttcttgt cttattgcaa atttatagtc
      661 tattggaatg tccttaactt catctcggat actactaatt atttcgcttg caaatctact
      721 tctattatca cacgttccac catattcatc atttctatta ttaaatatac ttgatgaaaa
      781 acttcctaca agcctatcac catgaatttg aatcatgtca aaacctgctt tttttgcatt
      841 caatgctgtt actttaaata aatttataat atttttaatt tcttctttgg gcatatttgt
      901 tatgtaatct tttactccgt cattcattat tttttttatc tcatcatgtg aagtaattcc
      961 catcttcata gtatctttaa ttaaattaac atcataatct gaacaaaata gttgtgctga
     1021 tacctttgca ccagaattgt gtatttcatc tacaattttc ttgtatttaa tgactccatc
     1081 ttcatccgat aggcttatag ctaccttatg aaaactaggt ctaatagata catctcctag
     1141 agtaatcaga gctactcctg acttagcaat atcagaaaac tttttaattt tttcttccaa
     1201 tttaagaccc atgcttgtag gtgcaaaaga tactctattt tttaattcca aatttccaat
     1261 tttaattggt tttaataaat tacaatacat cctatccttc ctccacagct gtttttatat
     1321 cctttaccac atgtaaattc tttaccagtt ctttatattc tgtatctgag aactcttttt
     1381 ttatgtggtt atcccacttt gaaaatatgt tttttatatc ccctaatact tcctcaccct
     1441 tatctgttac tctcaactga aaagctctac tatcattagg gttttggatt ttttctatgt
     1501 atccatcttg ttctaaccta gatatagttc ttgttgtatg agctttatca acttcaaatt
     1561 ctgtagaaac atcattcaaa gaacaattcc tatttttatt aatataaatt aaatagaaat
     1621 atagaccatt cgtaagttta tatggtttta aacatttttc acaataaagt ttaaagtttt
     1681 tttgcaagtt acaaataata tatgacaaac tttcatactg taaattttta aaatccatct
     1741 taaatttccc ttctataatt ataatatgtt tgactatatc aactatatta tattaaacaa
     1801 ttaatatagt caagaatatt ttattctcta aatctatgtt ttattaattc tttaaaaaac
     1861 tattatataa aataatcatg ataaaattag aaattggaat ttttaatatg cactgtacat
     1921 aaatatattt tatataaaag tttatatttt caaacaagta atttttcgaa aattgtctaa
     1981 attcagtaaa aatatggtaa tatatacata agcaatataa atctataaaa aggagtgtta
     2041 catatgatat ctaataaaat gcaaacttta gttgcaaata gttctgttat aagagctatg
     2101 tttgaagaag gaaagaaact ttctgatatt tatggtgagg aaaatgtttt tgattttagt
     2161 ataggaaatc caagtgttga acctccagag actattaaag cagttataaa tgatatttta
     2221 aatgaagaat ctccaaattt agttcatgga tatatgaaca actcaggata tgaggatgta
     2281 agagatgcta ttgctgaaca tataaataaa aaagatggat taaatcttac aagagaaaat
     2341 ttaattatga cttgtggtgc tgctggtggt ctaaatatta ttttaaaaac tcttttaaat
     2401 cctggtgatg aagttattgc ttttgcaccg tattttggtg agtataaaaa ttatacagaa
     2461 aactatgatg gaaaattaat agaagttcct acaaatatag agacttttga accagattta
     2521 gatgctctaa aaaatgctat tactccaaaa acaagagctt taataataaa cactccaaat
     2581 aatcctactg gtgtcatata ttctgaagaa ttattaaaaa atcttggaga attattggat
     2641 tcaaaacaaa aagaatttaa tacaagcata tatctaattt ctgatgagcc atatagagaa
     2701 ataatttatg atggtgccaa agttccttgt gtactaaaat actatagaaa ttcatttata
     2761 gggtactctt atagtaaatc attatctcta cctggtgaac gtataggata tattgttgct
     2821 aatgggcaaa tggatgattt tgatgatgtt atgtcttcat taaatgttgc aaatagaata
     2881 cttggatttg taaatgctcc ttctcttttt caaagggtta ttgcaagaag tttagatgca
     2941 gaagttgatg taaatattta taaaaagaat tttgaccttc tatataatag tttaatcgat
     3001 atgggatatt cttgtgttaa acctaatggt acattctatt tgttcccaaa agctccaatt
     3061 gaagatgata aaaaattctg caatgatgca aaacaattta atttattatt agtaccaggt
     3121 tcttcttttg gttgtccagg tcattttaga gtatcatatt gtgtatctta tgataaagtt
     3181 aaaagttctt taccagcatt tgaaaaatta gccaaattat ataatttaaa ataactaaat
     3241 caaagtaatt caaataatta actaccttag tatagaatac ttacattcta tattaaggta
     3301 gtttataatt ttatgtacta tattttatac ataccatatt attccaatat gcttgaatat
     3361 tcttatctat agtactaata taaattacaa ggaggtgttt gacttgaaaa aaggttatgt
     3421 ttatataata ctgactacct tattttttag ttcaatggaa attagtctaa aaactgtcac
     3481 taatgacttt aatcccttac aaataacttt atcaagattt tttgttggcg gtttagtctt
     3541 actacctttt gctgtaaaaa gattaagagc tcttagtctt tctattacaa aatcagactt
     3601 aaaatacttt gcatttttag gttttatgtg tgtagtagta agtatgtcat tgtatcaact
     3661 ggctgttcta aacacaaagg catctgtagt tgctgttttg ttcagttgta atccagtctt
     3721 tgtaatgctt ttagcttact taattttgaa ggaaaaaata tataggcaca atgtaatttc
     3781 acttatatta gaagttcttg gaattatagt tataataaat ccattgcata caaaactaac
     3841 tcttagtgga atattcttaa cattatcttc tgctattatt ttttcaatgt atactgtatt
     3901 tggtaaaaga aaaaccttaa aatttggtgg aatagttgta acttgcttta gctttatatt
     3961 tggtagtttg gaaatgttga tattggtttt actcactaaa attaatttta tcgcagatat
     4021 attaaataaa aataaacttc atatatttgc aaatatccct atttttagtg gatatacctt
     4081 acacaatatg cccattatga tttatgtatt cgtatttgtt acaggtgttg gttatgcact
     4141 ttactttatg gcaatggaag ctacatctac tagtcttaca tctttagtat tcttctttaa
     4201 accagtacta tctccaatac tagcattatt aatacttaaa gaaattatcc ctataaacat
     4261 ggttatagga attttattga tagtaattgg ttcaataatt tctattatac ctacgataat
     4321 tactcaaatg cataataaac acgttgaagc cttgtataag gagtagtaat tgataatcta
     4381 tcaagttata cataagacaa aatttattag atttaaacgc aatataaaag agatgctatt
     4441 ataatagcat ctcttttata tttattttaa atttattaaa gctctattta gctaggtttt
     4501 gcaaaaagct ataagtttgt ggacaagctg attttaactt actatttgta tcttgattta
     4561 aatagtaata tgcaaatgct tctgcaaaaa attcttctgg atatacacct aagtagttta
     4621 cattacctaa agaacgacct tctttagcaa atatttgttt gaattgtgct gatttagata
     4681 tatcatttaa tactatatgg tctattgcat gtgctgtttc atgtaattct aaatttattg
     4741 catcatgccc tttacctttg ttactaaatc ctattctaag agctactgta cttccaccta
     4801 agcctggaac atcatcccaa gtttttccag taccttccca tcccttagga actacacctt
     4861 ttaaataagc atattctttt tcatctgtta actttccact taataatttt atttttaagt
     4921 tatcttgctt taatacattt aaatactttc catctatatt agctaatcta tttaccatag
     4981 cattagcttc gtttttattg taatttccag ttggaaaaac tactatttga ctaagtgtgt
     5041 ctttattttg ttgtatagta gtactatatg catgtgcact tactggaact gaacttatta
     5101 agaatattga tattatagct attaataatt ttttacttgg tctcatatta ttccctcctt
     5161 tgagttaggc cgggagtaat aaatttcaaa ataaaaaaga tacccaagag tatctttgta
     5221 tatacaaaaa gaaattttta ctcttttcgg caactggctg gcatggttta ctaaacttta
     5281 gcccctatag ctttgcgtga ctaggtttcc ctagttttgc ctcatttaat tttatatcta
     5341 tattatagct tatatctttt taattgtcta tatccctttg gaactttttt ctaaaaagtt
     5401 attatttttt tacataaatc ttcaaaaaaa aatatcttct aacaatattt tcattattaa
     5461 atattgtttt agaagatatt ttttaatata acttatattt tttataatgt tagggtctaa
     5521 tttgtatttt tatttcttct taatacgaca agtcctacaa tagctcctat aactaaaagt
     5581 atttctccaa taattgtagt actatcccct gtttttggtg gtactggtgg atttaccaaa
     5641 gtatcatctt tagctttatt atttttttct tctgacactg atggctttac cacttctggt
     5701 attggaacaa tctgtttaac aggagtttct atcacctctt ctgatggtgg tactggtgga
     5761 ttcaatatct ctggtattgg aggatttatt atatcttctg acggtggtac tggtggattt
     5821 ataactatag tatcctctgt atcagatgga tttgatggtt tccttggttt atctgtgctt
     5881 ggtggcactg gtggatttac tattggttca tctgtatttg gcggtacagg tggatttact
     5941 ggtggatttt cttgtcttat gttttctata tttccgatat ctactattct accaatatct
     6001 ttattaccaa tttcaacctt aattttatcc ttcagttttt catatccact tggagccatc
     6061 acttctacta aataatatat tcctggtttt tttacactag attgaattac accatcttca
     6121 tcactaacta aatccttaac tactatattt ccaaatgcat cttctaaatt gaacttagca
     6181 cctgaaagta catttttatc taaagcatcc acttttttag cttcaaaagc ataaccttgc
     6241 ttagtagtct ctactcccgg aggacttgaa ccattaatct gagccacatt ttgtatagtc
     6301 tccccaactt ttacatttgt gaagtctgca tcaaatgtaa cccagctttg cacaggttcc
     6361 ccttctttta tctgtttaaa ttcgtattta tttactaatc ttattgtatt ttttccatct
     6421 ccagcttctt ttttaagttc aagattatca gaatatttta tattagatat ttttagagat
     6481 gggtttactt catccaaaag atttacttgt cctgcatcat aaaccccata agttgacata
     6541 ttgattttgt atttaacaat ctggttatca ctactattta aaaccttttt atcaacttct
     6601 ttttttgcgc ttattaatcc agaatttttc ttaaagttta tctcatcatt tttatcaatt
     6661 tcactattat ttgcatcaag gacagctcta tttatataac tatcttcaat actaattacc
     6721 tttaatgtat aagctataaa aaactttgat tctacttctt ctttactgag attaattgta
     6781 aatccagtta taactttatc tacttgccca ctttcatttc ttttttcttc tactttatat
     6841 gaaatattat tggcaatttt ttctttactc caaggagtcc agctcccatt cattggaact
     6901 tctacaactc taaaatcatg cccatcctct cctgaagtag tcaatctcat accttctggt
     6961 atattatctg ttataacaac attacttatt ggtgatttat catcatttat tgaaatctga
     7021 tagtttatta cttgaccaac ttgagtaata tttgttgctc ctgaatgtcc tttagtaaga
     7081 agataattat ctcctctatc aaatatactt acagtagcat catcttcttg tatcttctta
     7141 ccatcagatt caatcctagc tacattctta tatttattac catgttttgc atttttgtca
     7201 ctgattctag ccttatactt aacagtatac gatttatcta tatttccaaa attaactgaa
     7261 atagaatttt tactctgttc aatattaaaa tcactaactt cttttccatc acttgttact
     7321 acacttacag aaccatttat caatgtcaat ccttcaggaa gctcatcata caaaataata
     7381 tcttttaact cttcctgctt ttcatttact tgtatactgt aatttatatc tttattttta
     7441 actggcataa atacagtagt tgattttctt ccttcaacaa gctttttaag tgttccttta
     7501 gcatctggaa catccgtttt atctccaggt tttatttcta catctatatc tccacttcca
     7561 ctttctattt ttccagtggt ttcaatatgt atttttgcat tagtatcttc atcaaccttt
     7621 ttaacatatg cttccaaacc tattttacct tgcattacac tttggccatt aggtaattct
     7681 ctaaatgtaa gtgtatactc tccattactt tctgttttat caaagcattc acttgtataa
     7741 tctaaattaa ctttattgaa tacatctggc accttaaaag ttattgaatc tcctgcttgt
     7801 attccttttg atgttggagt ataagttaaa ttaaatgata tttttttcat tgattccgtt
     7861 tctattgtat tgttattaat ttttacaaca aatccatagt cttcattaag ttcttcttct
     7921 aaaactttca ataaattttc atcttctaat agattatctt cctctggagt tttttctgta
     7981 tttttattgt ctagtggttt ttcatcttct aaagcttgtt ctgacttttt attatctgtt
     8041 gacttatctt cttctggtat ttgctctggc tttttattat ctattgactt ttctccttct
     8101 ggagtttgct ctggcttttt attatctatt ggcttttctc cttctggagt ttgctctggc
     8161 tttttattat ctgttgactt atcttcttct gaagtctgtt ctggtttttt attatctgtt
     8221 gaattatctt cctctggggt ctgttctggt tttttattat ctgttgcctt atctttctct
     8281 ggagtctgtt ctggtttttt attgtcgctt tccttctcct ctccagttga tgaattagtt
     8341 gaaccacttt gaatctgact attctctcct aattctgaag cataagatac agttggatat
     8401 attgtagaca ccaccatact taaaatcata attaaactaa ttaataatgc ctttttattt
     8461 cctttcttca tataaatttt ccccctctag gttatctata gtttataatc ttccattaat
     8521 atcgtatata aattaatttt tactaaaaaa ttatataaaa aaagctatga aaataaataa
     8581 atttatattc atagccggtt gcaccactga ctcagtatat ccataaggtg cccaataata
     8641 gaatatactt caacatctct ataatatttc ataaaaacaa ttaaaattgc tttatttata
     8701 ttaaaaatac aattatatac ttctattata ttatgcctct atactattgt ctatcttttt
     8761 tacatttttt accttttatg agattaatta ataattaaat aaaatcctta tctacaacaa
     8821 ttacacaatt atattcagga tttatctcct taactaattt tgttatatct tcttttaagt
     8881 catcctctga catgtctttg gaaaattcgg aaggattaac tactatatca aatattaaat
     8941 tcttcttgct tccttttcca actattctaa aatcatgcat agattttaca agactatttt
     9001 tcttaagtat ttcttcaagt tcttttttgg ctgacataac ttctttatct tcaagacata
     9061 ttgggtccat gtgaattact agatatatat ctaatttttc agatatttct ctctctgcag
     9121 tatctataat ttcatgtatt tccattatat ctatgttgga tggaatttct gcatgtatag
     9181 atgcaataca tctaccaact ccatagttat gaataattaa atcatgtgta cctattatat
     9241 atttataaga taacaatagc tctataatag aatttaccat ttcttcatcc ggtgcttctc
     9301 ctaaaagagg atttatagta tcttttacaa gagagaaacc agcataaagt atcactaatg
     9361 atactacgat accaacatat ccatctatag gaaaattagt aaatctagct acaataaatg
     9421 atataactac acaacttgaa gtaaatacat ctcctaaagc atcaagtgaa actgctttta
     9481 aggctgaaga atcaatttta tttcccacaa atttattaaa acgactcaac cagattttaa
     9541 tcattataga tacaattaaa agtataagtg gtattacttc aaattttaca ggaattggat
     9601 ttactatcct ttctatagat gactttacaa attgaagtcc aaccaacatc accataaatg
     9661 ctactattaa tgctgataaa tactctattc ttccatgacc aaaaggatgt tctttgtcag
     9721 ctggcttact tgctaattta aaacctatca tagttattgc tgaagatgcc atatcagaaa
     9781 gattattaaa tgcatcagcc attatagcta tactagatgt gaacattcct atgaatacct
     9841 ttatcacaaa taaaagtaaa ttggacaata tacctactac accagctaca taaccatact
     9901 tatttctaac atctgtattt tgaacgtttt cgctatctct gataaatgtt ttgactagga
     9961 ttttggaaaa catgaaactt acctccctgc cctttatttt attaacaaat tttataatct
    10021 atatctttat ttatgataac ataatttata tataaaattc ttaaaaatca ctctacttca
    10081 gtaaaatatt attctatata tctatttaga tacaaatttt atatttcgta aagtttttat
    10141 ggcttagtgt ctgtttaata gattctatat aagtttttac aaagattatt tattatgata
    10201 atatcatttt tcccaagtat tacttagaat atgatttttt tgttttgtct ttacatattt
    10261 taaatttata ctatatttat gtttttataa ccttatgata cactataact ataagatttt
    10321 aaacggaaag gaatgaaata aatcatgttt tttatcagtg atatttacac aaaatcacct
    10381 attaaatttg atactccatt gcaaaaagag gtatacaaaa tattacaaaa gttagatatt
    10441 gactttgaac gtgttgacac agatgaagca attacaatgg aagattgtgt tcagattaat
    10501 aaaaaattaa atatgaaaat ggtaatataa aacaacatta aacaaacaaa aaccgcaaag
    10561 ttacaatata tagtactttg cggtttcata agaattaatt tttactatta gagttcatac
    10621 ttctactatt tttcattgtt ctaagtatta gctttacaaa ttcatttgac aataatatag
    10681 tggatgcaaa tagtattatt tttatccaca tatcaaagtc caaagaaaca gaattaaaga
    10741 aactctggaa cacttgtgta aatattattt gaattatccc tgtaactact attatttgca
    10801 atgccagttt atttttaaag aaatttggta ttgtactatt taaaccaaat tctctacaat
    10861 ttaatgcatt aaaaagggca ctgaacgcaa ataaagaaaa tataacagta ccttgttctt
    10921 ctgatgtagc tcccaatata ttaaaagctg attgagtaaa tacaattgta attataagaa
    10981 tagcatttat aataatattt acaaacatag acctagctat tattccagaa tgtctattta
    11041 ttggttttct tttcaataca taatctctaa caggttctaa tcctaatgct agggctggag
    11101 gaccatccat tattatattt acccataata attgtattgt agtaaatggc atatccttac
    11161 cagtaagttg agatattata gcaattataa atgctactat atttacagta agctgaaact
    11221 gtataaatct ttgaaagttc tcatatatac ctcttcccca ttttattccc tctactatag
    11281 tactaaagct atcatcagtc aatattatat ctgctgcatt tttagatact tctgttcctg
    11341 aaatacccat tgcaattcca acatctgctt gactaagagc tggggcatca tttataccat
    11401 cacctgttac agctacaact tcgccacttt tttgaagcgc tgaaactatt ctcatttttg
    11461 tatctggttt acttcttgca acaatagata ttcctttaat ttcttctctc agttctttat
    11521 ctgtcaatac atctatatat gttgcttcaa ctgccttttt cccatcattt aataatccta
    11581 attcatttcc aatagccgtt gctgtattta tattatctcc tgtaagcatt tttacatcta
    11641 ctcctgcatt aaatgcttta tcaatggaat ctttgacccc ttctctcaat gggtccacta
    11701 ttcctacaaa tccactaaaa actaaattat cttccttcat ataacttctt gaatttccta
    11761 ttaaattcaa ttcaccttct gaagtcattg caacttctgt tttagaatta ctcatttttt
    11821 tataagcaaa tcctaatgtt ctcatagatt taatttgtaa cttcttaatc tcatctaaaa
    11881 tacttttttc tacttttgga gttattggaa caatattttt tccttgttgt acataagaac
    11941 atttttttaa taatacttct ggagcacctt ttgaaagtaa tatatctgaa tcctcttgac
    12001 gaattaatgt tgacatcttc ttttcttctg aactaaatgg tatttgtgat atcaaatacg
    12061 tttgttttct catttcatta tagttcttat cattatgata taaaagtaat gcacactctg
    12121 ttgcacttcc tatatattta aatgaattat cttctttttc tatatctgca gttgaattta
    12181 ctatacagtt ttgttcaaaa tagctgttac tttgatactc tcctccactt atatatttac
    12241 catcaacata tgctacctct accatcattt tgttttgtgt taaagtccct gttttgtcgg
    12301 aacatattac agaaacagaa cctatagttt cacaggcttc tttctttgtt actaatgcat
    12361 ttatctttgc catcttttgc attgttatag ctaaggtaat atttatcata gttggcaaac
    12421 cttctggaac agttgcaact attaatgcaa tacaaaccat atatgcattt ttagcaggtt
    12481 ctaatgattg taagaaagat aatatactgc ttgtatctaa aattaacata ccttttctct
    12541 gcatctgtat aatcataaac atacacaata aagtagctat tacgcctgat attcctgcta
    12601 ttttagcacc caacttccct aatttaattt gaagtggagt ttgctggtct tcatttgata
    12661 aattctgtgc tatcttaccc atctctgtct tatcaccagt atgagtgaca accattatgc
    12721 ccctaccata tgctacaaga gtccctccaa ataccatatt gacttgcttt gcaggtattg
    12781 catcctgttc gattatttct gttttagaat aaactacttc catatctaat acagcatcag
    12841 cattcttagc tacatcatca gattctcctg ttagcatatc ttctctaagt ttcaaattta
    12901 tagactgtat aagtcttcca tctgctggta tcatatctcc agtttctata tatacaatat
    12961 ctcctggtac taaatcattt tttgatattt taattatctt tccatttcta agtactttta
    13021 cttctatatt ttctgttaat tttgacaggg cctgagctgc ttttttagat tttccttcag
    13081 ttattatgcc tatagaaatt ccaataaaaa tagcccctaa aatacctaat gcatcatgta
    13141 attctcccac aaaagaactt attactgctg ctcctatgag aattaatatc ataggttctg
    13201 tcaaactttc tcccaactcg tcccaaaatg ttctaccttc ttttatagta aattcattta
    13261 atccatatct aagcttcctt tcttctactt cattatcatc aagtccaatt tctggatttg
    13321 tttttaagta ttttaatact tctttggtag gtttattata atacctcata actttatccc
    13381 ccttgttaat tatctataag gaattatatg cttatgatag cttgtatatt acttttcaaa
    13441 aaaaataagg tgttgattaa tcaacacctt atagtggtta tatattatta aattttatgt
    13501 tacaggcttt ataaattgtg agctatacaa atcaaaatat ttaatcttca aaataccctt
    13561 ctggatataa tgggaactta gatataagtt cttgtgcctc tgctttacat tcatctaata
    13621 cttctttatt atcaatattt tctgctacct tattcattat tcctgctatc tgtataactt
    13681 ctttttcttt cagacctctt tgagatattg atgtaagacc tatacgaaca ccactagtta
    13741 caaatggtga ttgtgggtcg tcaggtataa catttttatt aactgttatt cctacatatt
    13801 caagagcttt ttcaaattgt tttcctgtaa gattcttact tcttaagtca accattacta
    13861 tatgattatc agtacctcca cttacaatac taaaaccatg tgaaatcagt tcagaagcta
    13921 gagtctgagc atttactaca acttgctcca ttatcttttt aaatttatct gtacttaaat
    13981 ataatagtga aaaggctttt gctgcaactg tattaagatg tatagaccct aatgttcctg
    14041 gaaaaacacc tttatcgagt ttctttgcat gttctgcttt acaaagtaca ataccacttc
    14101 ttggtccaca gaaagtcttt gtcgtagatg aagaaacaaa atctgcataa ggtacaggac
    14161 taggtattac tttcgctgcg actaatcctg caacatgtgc catatctacc ataaagtaag
    14221 ctcctacttc ttttgcaacc tttgatattc tttcataatc tattaatctt ggatatgaac
    14281 ttgcccctgc aattataagt tttggtctac attcttttgc ctttgcttca agagcatcat
    14341 aatctatacg tccagtattt gggtctaccc cataaaattc atatttataa atgtcatgta
    14401 aaaaattaac tgcgctacca tgtgtcaagt gtccaccttg gtcaagacgc atacttaaaa
    14461 cagtgtcatt tggttttaat attgatgaat atacacaata gttagctgta gaacctgaat
    14521 acggttgtac gtttacatgt tctgctccaa atacttcttt tgcacgtttt attgctaggg
    14581 tttcaagttt atctgcttct tcagaacctg cttgaaaacg agcccctgga tagccttctt
    14641 ctgttttatt tgtaaataca catccactta attcaagtac ttctgttggt gctgtacttt
    14701 cagaagctat catctcaata ttgtgttctt gtctaaccaa ctcatcagct acaatcttgt
    14761 ataactctgg gtctgaaatt tttgttgttt ttaacataat aatcctcctc ttaattaaag
    14821 aatatatttt attagtttaa tcttcattga taaatttatt ataatggtct ataaaacgta
    14881 agatattcct ccaccaggtc ctaatggtat gccaataccc atgaatagta acaatattat
    14941 tatttctatt aatgtaaata ccactgagta tggaatcata ttcgatatga cagtacctat
    15001 acctatatct ttatcatatc ttctggcaaa ggccaatata actggaaaat acggaaaaag
    15061 tggacttatt ggatttgttg aagcatctcc aatacgataa gctatttgag ttaatgctgg
    15121 attaaagtct agtagcataa acatgggaac aaatataggt gctaaaatcg cccattttgc
    15181 agaagcactt cctacaaata aattgataaa tccagatagc aatataaatc ctattatcaa
    15241 tccatagcta ggtatccccg actctgctag taattttgct cctgttattg ataaaattgt
    15301 tcctaagtta ctaagattaa ataaattaat aaactgggat gctataaatg ctaggactat
    15361 atatccaccc atatcactca tactactacc catcatagat actaaatctt tgtcactttt
    15421 tatcttctta cttacttttc catacactaa tcctggagtt aaaaatataa tagtgattat
    15481 aggaactata cctttcatta aaggtgcatt actagatagt atagaaccag tctctggatc
    15541 tttcataaat gcattgtcac ctatacataa ggcaactatc actactacta caactaacaa
    15601 tgataataaa gcgtatttta tacccttatt ttcaagttca ctcaattcct gtatatcctt
    15661 atcatttgtt gaatcattat attttgtaaa acgaggagct ataaattttt cagttacaaa
    15721 tgctcctgca aaagttaaaa ctatcgctga tataaaagca aaataaagat tcattgctgg
    15781 attgccttgg taagatgggt ccatcatttg agctgctggt attgtaaatc cagctaacaa
    15841 tacatctgta gtactaagca taacatttgc tgcaaatccc cctgcaacac ctgcaaaagc
    15901 tgcaaacata cctacaagag gatgtcttcc aattcctaaa aacacaagtg ctgcaagtgg
    15961 tggtaatatt ataaatccta catctgctgc tgtatgtgat aacatacctg caaatacgat
    16021 tgctacagtt acaagttttt gtggaacttt acttataccc tttttcatta acacttccat
    16081 aaatccagat ttctcagcaa cacctgctcc aagcattgta accagtacta atcctaaagg
    16141 agcaaatgac tggaagtttg taactatgct acctaaatat gattgaatct gctctttctc
    16201 tagtagattt actaccttta caacttcttt tgtagaagga tgtatttctt ctactcctaa
    16261 attagatata actgctgaca atattacaac aattatacat agtaataaaa atatggttac
    16321 tgggtctgga agtttatttc ctgctctctc tacaacattt agtgccctca tcaataatcc
    16381 actatctttg tttttttcct gtgaattaat tttcctcaaa ctaatacccc ctcataaact
    16441 ttatctccag aatgctctat cttaaatttt attttttaat ttatccatat aatttataac
    16501 agactgacat agtacatttg tacctaccaa tatagaattt ttatcagctt taaatttagg
    16561 attatgccac tgatatatac aatcttgttc tttattgcct acccctaacc agtaaaaaaa
    16621 tcctggggcc ttttccataa atatagaaaa atcttctcct cctgtagaag gtattggatc
    16681 aactatagca tcttctgaat acaaatcaca cacagactta caagctattg tgtacatctc
    16741 tttactattt ataacagctg gtaaatcaaa taaataatct agctttgcag ttgcttgata
    16801 tccacgagct atctcacaaa ctatattttc taaattttct gatattttct ttcgtacttc
    16861 attactaaag cttctacatg tacctgtcat atctaccttt tctgaaatta cattatttgc
    16921 agtccctcca tttatagtac ctattgatat aacagctgat tctaatggac ttatgtttct
    16981 gcttactatg gtttgaatac ccattataat tgcacttgat gctactatag ggtctattgt
    17041 tctgtttggt atacctccgt gacctccaaa tccatttact tctatcttaa tagtgtctac
    17101 tgctgccatt aacccaccta acttaacacc tatttttcca caaggtatat ctggatgatt
    17161 atgaagtcca aatatagcat caacttttgg attttccatt actcctcgtt ccactagcat
    17221 cttcgcacct ttattgactt cttcggctgg ttgaaatata aactttacat ttccatgaag
    17281 actatctcta atatgagaca atacatatgc acatcctaca aggcaagatg tgtgtatatc
    17341 atgcccacat gcatgcatta taccatcata tctggattta tactcaatat caacctcttc
    17401 atatattggc aatgcatcaa tatctcctct cagtgctact gtgggaccat catacttccc
    17461 ttttaataat ccaacaactc ctgtttccat tcctaaatct aatatttcta tgtctaaact
    17521 tactaataaa tcttttatag cttttgtagt cctaaattct ttaaaactta attcggggtg
    17581 catatgaata tctgtaaaaa aatctaaaat atcttcttta tacttttctg agattaaaat
    17641 aagttcatgc atactaacac ctctccaaaa ttttattttt ttatttttta taatttaact
    17701 acaaattata taagttaata atctttataa ag
//
LOCUS       DAMJYN010000076        17629 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.079, whole genome shotgun sequence.
ACCESSION   DAMJYN010000076 DAMJYN010000000
VERSION     DAMJYN010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17629)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17629)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17629
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.079"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            354..536
                     /locus_tag="PC466_002832"
     CDS             354..536
                     /locus_tag="PC466_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770197.1"
                     /translation="MFKDKIDECVHIMTAYIASLKEYYSFIETQIGDFIKKYGEDVVE
                     LCLHRVMILLCECGLA"
     gene            complement(824..1026)
                     /locus_tag="PC466_002833"
                     /pseudo
     CDS             complement(824..1026)
                     /locus_tag="PC466_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003381593.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
     gene            1368..2282
                     /locus_tag="PC466_002834"
     CDS             1368..2282
                     /locus_tag="PC466_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2935 domain-containing protein"
                     /protein_id="HDF2770198.1"
                     /translation="MIDNQKYVILSLELHLFFSRIMKEHALFLEAGFTNKNYNLAMEA
                     DHYKKQFEDLLSYTVSASNGIIRPDILYSEELVTTLTSVAEQKTEEFTGIEINKDITT
                     RELNLQSGVNPQVGQDLVNYVAQLNSDAIRLLDGLINFKERVLDGVLSCTIFTSNYPL
                     LLEHIIHEANLYRSYVVDLENKIDIESKNAKEIELFWDHIMMEHALFMRGLLDPSEGE
                     LINTSNDFAIKFNELIEKTNEMTDSNIKNITEETLNETVEFKDFKEAGASGIEQCKIK
                     SIILPLLADHVLREANHYIRILESYKNM"
     gene            2672..3319
                     /locus_tag="PC466_002835"
     CDS             2672..3319
                     /locus_tag="PC466_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate utilization protein"
                     /protein_id="HDF2770199.1"
                     /translation="MIRQTPLEKRYDKLGPHIVTAFKKRYFDAYYCKTRNEALQQILD
                     LIPQNHVVSWGGSETLKEMGVQTAVREKGFKVIDRDLAKTPEERTEIMRQALLCDTFL
                     MSSNAISEDGQLFNIDGNGNRVAAMIFGPKNVIVVAGMNKIVKNIDDAIQRTRTIASP
                     AVVQRFQDVNTPCYINGSCIDCTSPESICAYMVTTRISRPAKKIKVILVGENLGL"
     gene            complement(3486..4055)
                     /locus_tag="PC466_002836"
     CDS             complement(3486..4055)
                     /locus_tag="PC466_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770200.1"
                     /translation="MKKFILCIIMFAISVLVLAGCTNDNKIKNEVDSMFNSIKTQDAD
                     TVDKYFPKSGLGNLIYEDKEGFKMYSKNMTWEISDIKNNKDKVTVDLKINNTDMVSIL
                     KKNPPKLGEMMPNPTMKDIDSAKKKEFNITLELVKSGDNYVCKVNQESAMKLLNVITG
                     GGIDYLADYNKDYYKQLDEEQKNYENKNS"
     gene            complement(4060..4959)
                     /locus_tag="PC466_002837"
     CDS             complement(4060..4959)
                     /locus_tag="PC466_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDF2770201.1"
                     /translation="MKLLSKVNNNIRLIIQVAFTALTNGYVNGFLEGTIYGGESKKLC
                     VPGLNCYSCPGALGACPIGSLQAVLSSREYKFSFYVVGFLMAFGAFFGRFVCGWLCPF
                     GLVQDLLHKVPFPVKIKKVYGDKYLKYLKYIVLIMFVIILPVAIVNVAGGGNPWFCKW
                     ICPSGTLLGGIPLILGNENLRESIGFLFSWKLSILLLILLMSIITYRPFCKYICPLGA
                     IYGFFNPISIYRFKIDKDKCTNCTACQTKCKLDIPIYKDVNSPDCIRCGECIKVCPQN
                     AITTTFSKDKKENNICAKKYRGI"
     gene            complement(4970..5119)
                     /locus_tag="PC466_002838"
     CDS             complement(4970..5119)
                     /locus_tag="PC466_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770202.1"
                     /translation="MSNFIKDNKKGISIIAISIIFIALGTYRGETNTVLTKAIMICLE
                     CIGIG"
     gene            complement(5112..5696)
                     /locus_tag="PC466_002839"
     CDS             complement(5112..5696)
                     /locus_tag="PC466_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HDF2770203.1"
                     /translation="MKKFFMVVLGCIFVLGVISGCSKKESKPVEKNKSNSEWFSNLDT
                     EDVDGNKVTKEIFSNKELTLINVWTTWCGPCVGEMPELEALSKEYESNNSNVAIKGLV
                     VEVDKTDMRTGLSNEEKNLVKNIMKKSDATYQQLTVSEELKKTDFKRVMEFPTTYFVD
                     KKGNFVGEKVVGANSKEEWKKIIDERLKMVKANE"
     gene            6117..7442
                     /gene="cdeA"
                     /locus_tag="PC466_002840"
     CDS             6117..7442
                     /gene="cdeA"
                     /locus_tag="PC466_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MATE transporter CdeA"
                     /protein_id="HDF2770204.1"
                     /translation="MENLFTRKFTTFEFLKFVSPAIISMIFISLYTIIDGIFVSTLVG
                     SDALASINIVLPIINLVCGFGIMMATGGGAIVSIRMGENRQDEANSTFSFIVLFSLIV
                     GISFTVISYFFIKEISILLGATDKLLPYCITYGKVMILCTPFYILKFIFNYFARTDGN
                     SKFSLFLSVIGGVTNIILDYVFIKYFGMGLLGAAVATAIGIILTCVLGIIYFLSNKST
                     LKLRKPKTDFRLIRDTMINGSSEMVTELSTGITTFLFNVVALKLAGENGLAALTIVLY
                     AHFLMTSVYLGFAAGVSPLISYNFGAENSDKLKETFKHSLKFIFVSSLLVFIIALVFA
                     PFIVRVFVSPDNTVFKLALQGLKIFAFAFLFVGINIFASGFFTAFHNGKISAIISFSR
                     AFVFIIIGIIILPPMLNMTGLWLTVPFAEVITIFISILFIKKYKGRYKY"
     gene            complement(7537..8331)
                     /locus_tag="PC466_002841"
     CDS             complement(7537..8331)
                     /locus_tag="PC466_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2770205.1"
                     /translation="MNELKPYIKFFNKNTKLYIIIFMIVGIVMNILPVFILKIFGEAS
                     KTNLSTIVNPILTYITILLFVYGVNIANKDFSGALSIRADRKSCIKAIVIDLIILSFV
                     ISILGIVLIFLSKLFIEIITGYSIELSVLLKRDMIWTSISALIDPSTSSMPLTYLNYF
                     VQICINEICIGFIGVLLGAFTYRVRKVTSITILIGLPILMVIYIVNFATKNMHKMLLY
                     LEKIIYSFQNPFILFGTKVGIIVICIIFIILLLRKAPIKEYANDLL"
     gene            complement(8332..9207)
                     /locus_tag="PC466_002842"
     CDS             complement(8332..9207)
                     /locus_tag="PC466_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2770206.1"
                     /translation="MRSSIKIENLSHSFKKQNIFNNMSLNFEKNKIYGLLGKNGAGKT
                     TLLNIMVNQLIQNEGEIEILGKNPKEDIKVLEEVCIVREKEFYSPDFKVGQIFEFSSS
                     FYKSYDKGLEEELCKYFDLNTKKKYKQLSRGMKTILSNIIGICSNSAITIFDEPTIGL
                     DAVNRQEFYNIILDSYIKNPRTIIISTHLIDEIDDLLEHVIILNEGKIIIDEEIDVIK
                     QKAHYITGNKEELEKLECIKNIKPKKAFGNAVAYFYYGDFSENDEKILKNSNIDVGYI
                     GLQDMFVNMTKKEEL"
     gene            complement(9211..9579)
                     /locus_tag="PC466_002843"
     CDS             complement(9211..9579)
                     /locus_tag="PC466_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2770207.1"
                     /translation="MKLVLNNEEPIFIQIARAIEDEILSNGIKEEEQVPSTTELSKLY
                     KINPATVLKGINILVDKNILYKKRGIGMFVSDGAKTIIKEARKENFKHNFVKNLLQEA
                     NKLEINREELVDIIINFKED"
     gene            complement(9762..10421)
                     /gene="deoC"
                     /locus_tag="PC466_002844"
     CDS             complement(9762..10421)
                     /gene="deoC"
                     /locus_tag="PC466_002844"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HDF2770208.1"
                     /translation="MKHILKTVDHTILKATTTWEDIKILCDEAVDMSVASVCIPPSYV
                     KRASEYLKGKIKICTVIGFPLGYQTTATKVFEAKDAIENGADEVDMVVNISDIKNKDY
                     DNIGKEIKEIKKAIGDKVLKVIIETCYLDEDEKIKMCEIVTMSGSDFIKTSTGMGTGG
                     ATLEDIKLMKEHVGKNVKIKAAGGVKSISDAEKFIEAGAERLGTSSICKILKNEDTTD
                     Y"
     gene            complement(10457..12001)
                     /gene="murJ"
                     /locus_tag="PC466_002845"
     CDS             complement(10457..12001)
                     /gene="murJ"
                     /locus_tag="PC466_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein biosynthesis integral membrane protein
                     MurJ"
                     /protein_id="HDF2770209.1"
                     /translation="MSKVAKATFYLMIVTIISKILGMGRELVLSSIYGTGLYTESYLT
                     AMNIPNIIFAAIGTAIVTTFIPMYQDISSKQGEKQALKFLNNVLNIIVGICIVVAILG
                     VIFSKQLVSIFAIGFEGERFLLTVKFTKILITGIIFIGITSVMSAFLQIKENFIVVGF
                     GSIPYNIVIIISIMLSTVFGPYILPIGAVVAMVVQLLFYMFFVKKTNYKYLYYLNFKD
                     DSLIKLLALLSPVFIGVAVNQVNSLVDTTLASTLVKGSIPALTYSDRLNGFVTGTFTA
                     SIVSVMYPMLSKLSAENNQKKFTSSVKSSINMIIISMIPISVASIFFATPVVRIIFER
                     GAFDARATQMTATALIFYAVGMTAFGLRDILGKVFYSLQDTKTPMVNGIISVGVNIVL
                     DLVLIKPMAHGGLALATSSSSIACILLLFLNLKRKVGYFGQDKIIKATLKSVVASLIM
                     GVLSYFTYKFIFGILGVGTFNEFVSLAISVIVGGGIYTLLMTIFKVEEVDMILNIAKR
                     KLHLKK"
     gene            complement(12475..13359)
                     /locus_tag="PC466_002846"
     CDS             complement(12475..13359)
                     /locus_tag="PC466_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDF2770210.1"
                     /translation="MDTKKENNYENYICVGSSNVSNAMKMYLKEIEEYKMLSAGEEVE
                     LAKEIINSSSVAKEKFINSNYRLVVSIAKRYKRDSIDMLDLIQAGNIGLIKAVEKYDY
                     KKGYKFSTYATWWIKQSITRYIDDCENTIRIPIHLHQRINFVKKKKQELLNVLLREPT
                     IDEIADACGLEVDKVLELLRRDKNVVSLDTPLKEDEDSSLVEFIPSDADFKDVVIHEV
                     EQHNLKEKIEELLTGLGEQEQQVLRMRFGIDDDDPKTLEQIGKVFGVTRERIRQIEAK
                     AIRKLRHPSKLKQLKHFY"
     gene            complement(13650..14126)
                     /locus_tag="PC466_002847"
     CDS             complement(13650..14126)
                     /locus_tag="PC466_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction enzyme HsdR N-terminal
                     domain-containing protein"
                     /protein_id="HDF2770211.1"
                     /translation="MSKELVKDRVIKYLIEDLLVPQDMIDTNVELAEFEEGAEGVLDI
                     VVNVKDEEDYYAPVMIVQCLDEDVELEGEVLQKQIEFLEEVDNITMSGRLVLTNGDAM
                     MYADWRGEEYDTEAALPTYDIMVKEFHEMEQQAKDLEEHHHHDKNCGCGCNHHHEN"
     gene            14393..15568
                     /locus_tag="PC466_002848"
     CDS             14393..15568
                     /locus_tag="PC466_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HDF2770212.1"
                     /translation="MKFKKQISSIVVSTMLVLGSMNLSYADGTNVVTLGANLSESQKQ
                     QMLNYFGVKKDQVLVLDVTNAEERQYLQGVATEGQLGKVTISCSYVEPTKKGNGINVK
                     TANLTWVTSSMIASTLTTAGLEDANVIAAAPYPVSGTGALTGIMKAFEDASGKKLDET
                     KKEIASEELVVTGDLGDDIGQEKATGVMNDIKTEIVKNGTKDTNQIANTINNVVNNYN
                     ITITPEQKEQIKGVMKKIADQNYDYNSMKNTLDNVSDNVNEQLKKLGESVKGSGILDT
                     IGGWFSGIGDWFSGLFSGGDKKDLGILNNTNDESLGSDAVINSTEGVQINPQNNTNSN
                     NDSDTNSSKNDTSSNNENNDSSQTNENNTTNNSENQSNNNDSVGFFEKIKNWLSGLF"
     gene            complement(15649..16452)
                     /gene="proC"
                     /locus_tag="PC466_002849"
     CDS             complement(15649..16452)
                     /gene="proC"
                     /locus_tag="PC466_002849"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HDF2770213.1"
                     /translation="MKKIGFIGAGNMASAMIGGIVNSKLVEPNMVIASAYSQGTLDRI
                     DANFGINTTKDSKEVTRTSDIVIVAVKPDIYDDILEEIKDFIDDNKIIVTIAAGKSIK
                     DIESIIGEDKKIVRTMPNTPALVNEAMSSLSINKNINNEDLEAVTEVFNSFGNTEVVP
                     EYLIEAVIGASGSAPAYVFLFIEAIADAAVIAGMPRPQAYKFASQAVMGSAKMVLETG
                     KHPGELKDMVCSPGGTTIEAVKVLEEEGFRASVIKAICACIEKSKKMSE"
     gene            complement(16492..17076)
                     /locus_tag="PC466_002850"
     CDS             complement(16492..17076)
                     /locus_tag="PC466_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2770214.1"
                     /translation="MNKDIGAKIKQLRTQKQMTLKDMSEKTNLSIGFLSQLERGLTSV
                     ATDSLGKIASVLDVELTYFFMKPKEHKRAVLRSYEKEVFDVENSTFIHYHLSSSLKEK
                     TMLPRLIEILPSKSSEEICCYVHEGEEFVYVLEGTLTVFLGDEQIEMYPGDTIHYNSE
                     KNNHNWVNYTNKVVKILVVSIPNPFEKSDAVKEA"
BASE COUNT         6105 a         2775 c         1966 g         6783 t
ORIGIN      
        1 tacctaaaaa ataataaatt gcttagaaaa taatagatta caataactaa aattttaaaa
       61 ttaaattcct taaaagtatg attaattata attatataag tatattctta ttacacttat
      121 attaatttat attaaatatc tactaactca aatattcata attaaacttt aaactggata
      181 aattttcttt taagaatgaa agtttatcca gttttgcgat tataataacc agttttacat
      241 atccacttgt aaaatatatc taagcaatat atcatactat atagatttat gagtgaaata
      301 atatctgcta tttactgaat atttttattt ttcgtttttt agggggatta gttgtgttta
      361 aagataagat tgatgaatgt gttcatataa tgactgcata tattgctagt ttaaaagaat
      421 actattcatt catagaaact caaattggtg attttattaa aaaatatgga gaagatgttg
      481 tagagttatg tctccataga gtgatgattc tactatgcga atgtggtttg gcataaaatt
      541 aaatttatta aaatgggtaa gaagaatcct atataatatt cttcttaccc attttaatat
      601 atcaatttca tagcttatcg tttaaaatat tttacctcca ttactagaca actttacatt
      661 ctctttttaa ttctagtata tttaaatcat tttagttgct ccttatttat tcttattact
      721 tgttttattt tataaataaa ataattcttt ttaataatgt tttttgttga tattcctatc
      781 acacatccaa ttatttatca ttgtcttgaa attgtttgca tacttaattt aatccaattg
      841 aaacacccca gcatagaatc ccctgtaaaa tagaagttgg attaaatcct aacatccata
      901 cagaaaatac tactccaagc acaagcaata taatggaata tatttatcac ttaatttttt
      961 atacttttta aatcccatac ctaaaacatt aagtgcagct attagaatta ataattgttg
     1021 tggtataaaa ttatgattgc ttcatattta ttcatttttt gctataaaag ttcttgtttc
     1081 acaaaaaata tttgttttgt atcaaaataa tacttataaa ttacataatt ctcataaaaa
     1141 tttctagtat tacttgtgct cttaataaat aatagccaac aagtacctta aatcattata
     1201 tctatatcta ataagaaaca cagtaagata attttttcgc ccataactta ataaaaactg
     1261 ttgatattag tagcaattga atttagttaa tttatttata atatacataa atttaaatat
     1321 tacgaataaa gtattataaa taggatactt tctaaaggga ggaaattatg atagataatc
     1381 aaaaatatgt tattttatca ctagaattac atttattttt ttcaagaatt atgaaagagc
     1441 atgctctttt tttagaagca ggattcacaa ataaaaatta taatcttgct atggaagctg
     1501 accactataa aaagcaattt gaagatttat tatcatacac tgttagtgct agtaatggta
     1561 taattagacc tgatatatta tattcagaag agcttgtaac tactctcaca tcagttgcag
     1621 aacaaaaaac agaagagttt acagggatag aaataaacaa agacatcact acaagagaat
     1681 taaatctaca aagtggtgta aacccacaag ttggtcaaga cttagtgaac tatgtagctc
     1741 aacttaactc tgatgcaata agattacttg atgggcttat taattttaaa gaaagagtct
     1801 tagatggtgt actatcatgt actatattta catcaaacta ccctctactt cttgaacata
     1861 taatacatga agcaaattta tatcgttctt atgtagttga ccttgaaaat aaaatagata
     1921 ttgagtcaaa aaacgctaaa gaaatagaat tattctggga ccatattatg atggaacatg
     1981 ctctgtttat gagaggatta ctagacccct cagaaggtga actaataaat acttcaaatg
     2041 attttgctat aaaatttaat gaattaattg aaaaaacaaa cgaaatgact gattctaata
     2101 tcaagaacat tacagaagaa actctaaatg aaactgttga gtttaaagat tttaaagaag
     2161 caggagcatc aggaatagaa cagtgtaaga taaaatctat aatattacca cttttagcag
     2221 accatgtttt aagagaggca aatcattata ttagaatatt ggagagttat aaaaacatgt
     2281 aattaaaaat tacttttaaa ataatctttg catatttaga taaaataaag gtacagttaa
     2341 ctgtaccttt attttttata aacttataaa atttaaacaa gttattcata aaataaaata
     2401 atcatcatct ataacccaca actttatttt atattaaata aaaagtatta gtgattatgt
     2461 tttataagta tttctttatt cagttatttg ttaaaaacta atagtaaatc ttatactaat
     2521 cgcatattta tgttataact atattgtaac tattttcgta atcttaggaa aagattactt
     2581 ataaaattaa ccttatacaa taatatatcg tataatctta attagcataa tagttacaat
     2641 attaaaattt aaatatggga gtgattttag tatgataaga caaacaccat tagagaaacg
     2701 atatgacaag ctaggtcctc atattgtaac agcattcaaa aaacgttatt ttgatgctta
     2761 ttactgtaaa actagaaatg aagctttgca acaaatttta gatttaattc ctcaaaatca
     2821 tgtagtatca tggggaggat ctgaaacact taaagaaatg ggcgtacaaa ctgctgttag
     2881 agagaaagga tttaaagtta ttgatagaga tttagcaaaa actccagaag aaagaactga
     2941 aattatgcgt caagcacttc tatgcgatac ttttttgatg agtagcaatg caattagtga
     3001 agatggacaa ctctttaata ttgatggaaa tggcaatcgt gtagctgcaa tgatatttgg
     3061 tccaaaaaat gttatagttg tagctggtat gaataaaatt gtaaaaaaca ttgatgatgc
     3121 aatacaaaga actagaacaa ttgcatctcc agcagttgtt cagcgttttc aagatgtcaa
     3181 tacaccatgc tatattaatg gaagttgtat agattgcaca agtcctgaaa gcatttgtgc
     3241 atacatggtt actacaagaa tcagtcgtcc agcaaaaaaa ataaaggtaa tattggtagg
     3301 agaaaatctt ggtctataaa atatacatac atgtaaatag ctctataaat aataaaatca
     3361 tatgaaataa cttatttcta aaagtggtag aataaaagct tctacaagac tttcattcta
     3421 ccacttttat attcttttaa tttgtgtttc tatattatta attgctccaa ttttcatata
     3481 tattactaac tatttttatt ttcataattt ttttgttctt catcaagctg tttataataa
     3541 tctttattat agtcagctag ataatctata ccacctcctg taatcacatt taataatttc
     3601 attgcagatt cttgattaac tttacaaaca taattatcac cagatttaac aagctctaat
     3661 gtaatattaa attctttttt ctttgcagaa tcaatatctt tcatagttgg atttggcatc
     3721 atttctccta gtttaggagg attctttttt aaaatagaaa ccatatcagt attgttaatt
     3781 tttaaatcta cagtcacttt atccttatta ttctttatat ctgaaatttc ccaagtcata
     3841 tttttagaat acattttaaa tccttcttta tcttcgtata taagattacc taaccctgat
     3901 tttgggaaat acttatcaac agtatctgca tcttgtgttt ttattgaatt aaacatacta
     3961 tccacttcat tttttatctt attatcatta gtacaaccag ctaacaccag tactgatatt
     4021 gcaaacatta taatacatag aataaatttc ttcattaaat tatatccccc tatacttttt
     4081 tgcacaaata ttattctctt ttttatcttt tgaaaaagtt gtagtaattg cattttgtgg
     4141 acaaactttt atacattcac cacacctaat acagtctgga ctatttacat ctttatatat
     4201 tggtatatca agcttacatt ttgtttgaca tgctgtacaa tttgtacatt tatctttatc
     4261 aattttaaat ctatatattg aaataggatt aaaaaaacca tagattgctc ctaaagggca
     4321 tatatacttg caaaatggcc tataagtaat gattgacatc aataatatca atagcaaaat
     4381 acttaacttc cagctaaata aaaatcctat tgattctctt aaattctcat ttcctaaaat
     4441 aagtggtatt cctcccaaaa gtgttcctga agggcaaatc catttacaaa accaaggatt
     4501 tccaccccct gctacattta caatagcaac tggcaaaata attacaaaca ttattaagac
     4561 tatatacttt agatatttta gatatttatc accataaact ttttttatct ttactggaaa
     4621 gggtacttta tgtagtaaat cttgtacaag tccaaaggga caaagccaac cacaaacaaa
     4681 tctgccaaaa aaagcaccaa atgccattaa aaaaccaaca acataaaatg agaatttata
     4741 ctctctgctt gataaaactg cttgtaatga acctattgga catgctccaa gtgcacctgg
     4801 acatgaataa caattcaatc caggtacaca taatttttta ctttctcctc catatatagt
     4861 tccttctaaa aatccattta catatccatt tgttaatgct gtaaatgcaa cttgaataat
     4921 aagtcttata ttattattta ccttagataa taacttcatt cctcttctcc taaccaatac
     4981 caatacactc aagacaaatc ataattgctt tagttaatac tgtatttgtt tctccacgat
     5041 atgtacctaa tgcaataaat ataatactaa ttgcaataat agaaatgcct tttttattat
     5101 ctttaataaa gttactcatt ggcttttacc atttttagtc tttcatctat aatttttttc
     5161 cactcttcct tactatttgc acctacaacc ttctcaccca caaagtttcc tttcttgtct
     5221 acaaaataag ttgttggaaa ctccataact cttttaaaat cagttttttt aagttcttca
     5281 gatacagtca attgttggta agttgcatct gactttttca taatgttttt aactaaattt
     5341 ttctcttcat ttgaaagacc agttctcata tcagttttat caacttctac aactaatccc
     5401 tttatagcta cattggaatt attactctca tattcttttg ataatgcttc aagctctggc
     5461 atttcaccca cacatggtcc acaccaagta gtccagacat taataagagt aagttcttta
     5521 tttgaaaata tctcttttgt taccttattt ccatcaacat cctccgtatc taaattacta
     5581 aaccattcac tattactctt gtttttttct actggcttag attctttttt gctacatcca
     5641 gaaatcacac ctaaaacaaa aatacatcct aaaactacca taaaaaactt tttcatatct
     5701 cacactccta gaatttatat agtatataaa atggctgctt gaaataaaaa taacttctct
     5761 tctatattaa aacattatat ttaataaata agaactaatt taaaataagt tgtataaaag
     5821 atatatagtt aaaatctatt tcttttcaga caaaatctta tatatatata ataacttata
     5881 aagcttaaga ttatatacat atatttctaa aaattttctt aagaaacagt tattccttac
     5941 taatgcaata tacctatttt tactaatata agtttattaa ttagcattat actaatttat
     6001 cttaatatga ttttttgttg attttaagct gtttatcgta taaataaaat ttttcttgac
     6061 atatagttac tatatagctt attatagata gagagtaata aaaggaggta aaatttatgg
     6121 aaaatttatt tacaagaaaa ttcactactt ttgaatttct aaaatttgtt tctcctgcaa
     6181 ttatatccat gatatttata tctttgtaca caataataga tggcatcttt gtatcaacat
     6241 tagttggttc cgatgctctt gctagtataa atattgtact acctataatt aaccttgttt
     6301 gtggatttgg aataatgatg gcaacgggtg gaggtgctat cgtttctata cgtatgggtg
     6361 aaaatagaca ggatgaagcc aactctacat tttcttttat agttttgttt tcattgattg
     6421 ttgggatttc attcacagta atctcatatt tctttatcaa agaaatatct attttgcttg
     6481 gtgcaacaga taagttatta ccatattgta taacttatgg taaagttatg attttatgta
     6541 caccatttta tattttaaaa tttatattta actactttgc aagaactgat ggaaattcta
     6601 aatttagttt atttctatca gtcattggtg gtgtaacaaa tataatattg gattatgtat
     6661 ttattaaata ttttggaatg ggtcttttag gagctgcagt tgcaactgct ataggtatta
     6721 ttttaacttg tgttttaggt attatttact tcttatctaa taaatctaca ctcaaattaa
     6781 gaaaaccaaa aaccgatttt agacttataa gagatactat gataaacggt tcttctgaaa
     6841 tggttacaga attatctaca ggaattacaa cattcttatt taatgtagta gctttaaaat
     6901 tagcaggaga aaatggactt gctgctctta ctatagtatt gtatgctcat tttttaatga
     6961 catcagtcta tctaggattc gctgctggag tgtctccatt aataagctat aattttggtg
     7021 ctgaaaacag tgataaatta aaagaaacat ttaaacattc tctaaaattt atatttgttt
     7081 cttctctttt agtgtttatt attgctttag tatttgcacc atttattgtt agggtttttg
     7141 taagtccaga taacacagta tttaaactag ccttacaagg attaaaaata tttgcatttg
     7201 cttttttgtt tgttggtata aatatatttg catcaggatt ttttacagca tttcacaatg
     7261 gaaaaatttc agctattata tcttttagtc gtgcctttgt ttttataatc ataggaatca
     7321 taattcttcc tcctatgtta aacatgactg gattatggct tacagttcca tttgctgagg
     7381 ttataaccat atttatatct attctattta taaaaaaata taaaggtaga tataagtatt
     7441 aaaaattaat gcttaaaatc aacatttatt aaaactaata aacctgcttt aaaatacaaa
     7501 tttacaaatt tgatttttaa gcaggtttta ttttagttat aataagtcat ttgcatactc
     7561 tttaattggt gcttttctaa gtaataaaat tataaatatt atgcaaataa ctataattcc
     7621 tacctttgtt ccaaataaaa taaaaggatt ctgaaatgaa taaataattt tttctaaata
     7681 caatagcatt ttatgcatat ttttagttgc aaaattaact atataaatta ccattaatat
     7741 cggtaatcct atcaatatag taatactagt aacttttcta actctatatg taaaagctcc
     7801 aagtaatact cctataaaac ctatacatat ttcatttata catatttgta caaaataatt
     7861 taaataagtt agtggcatac ttgatgttga aggatctatc agtgctgata tagatgtcca
     7921 aatcatatct ctctttagta aaactgatag ttctatactg taacctgtta taatttctat
     7981 aaataacttc gataaaaaaa tcaaaactat acctaaaata gaaatcacaa agcttaaaat
     8041 aattaaatct atgacaatag cttttataca actttttcga tctgctctta tacttaaagc
     8101 tcctgaaaag tctttatttg ctatatttac tccatacaca aatagcagta tagttatata
     8161 tgttaaaata ggattcacaa tcgtggataa attagtttta gatgcttctc caaaaatctt
     8221 gaggataaac actggcaaaa tattcataac aattcccaca atcataaata taattatata
     8281 caatttagta tttttattaa aaaattttat atatggcttt aattcattca attacaattc
     8341 ctccttctta gtcatgttaa caaacatatc ttgtagccct atgtatccta catcaatatt
     8401 tgaattttta agtatttttt catcattttc actaaaatca ccatagtaaa aataagcaac
     8461 tgcatttcca aatgcctttt taggttttat attttttata cattctaatt tttctaactc
     8521 ttctttattt ccagtaatat aatgagcttt ttgttttatg acatcaattt cttcatctat
     8581 aataattttt ccctcattta atattattac atgctccagt aaatcatcta tttcatcaat
     8641 caaatgagtt gatattatta ttgtccttgg attttttata taactatcta aaattatgtt
     8701 ataaaactct tgtctattta ctgcatccaa accaattgtt ggctcatcaa atatggtgat
     8761 agctgaatta gaacaaatac ctattatatt tgaaagtata gttttcatac ctcttgacag
     8821 ttgtttatac ttttttttag tatttaaatc aaaatatttg cataattctt cttctaagcc
     8881 tttatcataa cttttataaa aactagaaga aaattcaaat atctgaccta ctttaaaatc
     8941 tggactataa aattcttttt ccctgacgat acaaacttct tccaaaactt ttatatcttc
     9001 ttttgggttc tttcctaata tttctatctc accttcattt tgaattaact gatttaccat
     9061 tatatttaat aatgttgttt ttccagctcc attcttacct aataaaccat atatcttatt
     9121 tttttcaaag tttagagaca tattattaaa aatattttgc ttcttaaaac tgtgagataa
     9181 attttctatc ttaatagaac tcctcatata ttaatcctcc ttgaaattaa ttataatatc
     9241 aaccaattct tctctattta tttctaattt gttagcttct tgaagtaggt tttttacaaa
     9301 attatgttta aaattttctt ttctagcttc ttttataata gtttttgcac catctgatac
     9361 aaacatccct atccccctct tcttatataa aatattttta tcaaccaata tatttatacc
     9421 ttttaatact gtagctggat taattttata aagctttgaa agctctgttg ttgatggaac
     9481 ctgttcttct tcttttattc catttgatag tatctcatct tcaattgctc gtgctatctg
     9541 aataaatata ggttcttcat tatttaatac taatttcata ggttcctcct ttctccatta
     9601 gttagttact caactaatta actatataac ttataatatc ttgaaaaata ttttctgtca
     9661 atactaaata aaaaacagag ggaaaattcc ctctgttttt tgttctttat atttataatt
     9721 aaattttgat ttttgtaatc ctatcccata agttaaaaac tttaataatc tgttgtatct
     9781 tcatttttta atattttaca tattgagcta gttcctaacc tttctgctcc tgcctctata
     9841 aatttttctg catcagaaat tgatttaact ccccctgcag cttttatttt tacatttttt
     9901 ccaacatgct ctttcataag ctttatgtct tctaaagtag ctccacctgt tcccattcca
     9961 gtagatgttt ttataaaatc tgaacctgac attgttacta tttcacacat ttttattttt
    10021 tcatcttcat ctaaataaca tgtctctata atgactttta atactttatc tcctatagct
    10081 ttttttattt cttttatttc ttttcctata ttatcataat ctttattttt tatatctgaa
    10141 atgtttacaa ccatatcaac ttcatctgct ccattttcaa tagcatcttt tgcttcaaat
    10201 acttttgtag cagtagtttg atatcccaaa gggaacccta tcactgtaca tatctttatt
    10261 ttacctttta gatattctga tgctcttttc acatatgatg gtggtatgca aactgatgct
    10321 acactcatat ctacagcttc atcacataaa attttaatat cttcccatgt agttgtagct
    10381 tttaaaatag tatggtctac tgtttttaat atatgtttca taaaatcctc ctaaatttat
    10441 aattaatata attagattac ttttttaaat gcaattttct ctttgcaata ttcagtatca
    10501 tatcaacctc ttcaacttta aaaatagtca ttagtagtgt ataaattcca cctccaacta
    10561 taactgaaat agctagtgat acaaactcat taaatgttcc tactcccaaa attccaaata
    10621 taaatttata cgtaaagtat gataaaacac ccataattaa agatgcaact accgatttca
    10681 aagttgcttt tattatttta tcttgtccaa aatatccaac ttttctcttt aggttcaaga
    10741 agagtaacaa tatacatgca attgatgatg aactagttgc aagagcaaga ccaccatgag
    10801 ccattggttt tattaaaact aagtccaata ctatatttac ccctacagat ataatcccat
    10861 ttaccatagg tgtttttgtg tcttgtaatg aataaaaaac ctttcccaaa atatctctta
    10921 atccaaatgc agtcatacca actgcataaa aaattaaggc agttgctgtc atttgggttg
    10981 ccctcgcatc aaaagcacct ctttcaaaaa tgattctaac aacaggagtt gcaaaaaaaa
    11041 tagaagcaac tgaaatagga atcatagaaa ttattatcat atttatacta gatttaactg
    11101 aactagtaaa cttcttttga ttattttctg cacttaactt agataacata ggatacataa
    11161 cagatactat tgaagctgta aatgtccctg taacaaaacc atttaatcta tctgaataag
    11221 taagtgctgg aatgcttcct ttaactaatg ttgaggctaa agttgtatct accaatgagt
    11281 tcacttgatt aacagcaaca cctataaata ctggtgaaag taatgctagt aatttaataa
    11341 ggctatcatc tttaaagttt aagtagtata agtatttgta gttcgttttt ttaacaaaaa
    11401 acatgtaaaa gagcagttga actaccatag caaccacagc accaattgga agtatgtatg
    11461 gtccaaatac ggtacttaac attattgaaa taattattac tatattatag ggtatactcc
    11521 caaatccaac tacaataaag ttctctttaa tttgcagaaa tgctgacata acactcgtaa
    11581 tacctatgaa tattattcct gttatcaata ttttagtaaa ttttacggta agtaaaaacc
    11641 tctctccttc aaatcctata gcaaatatac ttacaagttg ctttgagaaa ataactccta
    11701 atatagctac aactatgcat ataccaacta ttatatttaa aacattgttt aaaaacttta
    11761 gtgcttgctt ttcaccttgt ttactactta tatcttgata cattggaata aaagtagtaa
    11821 ctatagcagt acctattgct gcaaatataa tatttggtat attcatagct gttaaataac
    11881 tctctgtata taagcctgta ccataaattg atgataatac taattctcta cccattccaa
    11941 gaatcttaga gattatagta actatcatca aataaaaagt tgctttagct accttgctca
    12001 ttttatcact ccacttctaa catacctctt tttaatcaag taaaatttgg ctcattagat
    12061 ataattctat caactaattt gccttgctta gccctatcaa aatataatta acacctattt
    12121 cttaatatat cacaaactac attattcttc atattttttt atttctccaa taagttttac
    12181 atctttccta tataaattgt atagcttcaa ttatattcaa agaaatggag ttgctacccg
    12241 ataactttaa aagtaaaaaa cagattttat tatcttttta aactatattc taacatattt
    12301 tgtccatatt gagaaatttt actaaactat tatgtacttt attaaataaa taaaataaca
    12361 gcacacctat aaaatacaag tgtgctgttc ataaacagat tttataaaaa aataattcct
    12421 aagtagagat taacatgctt tctcatactc tcatatataa tgtgtctaaa aatattaata
    12481 aaaatgcttt aattgtttta acttacttgg atgtcttaat tttcttattg ctttagcttc
    12541 tatctgtctt attcgttctc tggtaactcc aaataccttt ccaatctgtt ctagtgtttt
    12601 agggtcatca tcatcaattc caaatctcat tcttaaaact tgctgttctt gctcaccaag
    12661 acctgtaagt agttcttcta tcttttcttt taaattatgc tgttcaactt cgtgtattac
    12721 aacatcttta aaatcagcat ctgatggtat aaattcaact aaactactat cctcatcttc
    12781 ttttaatgga gtatccaaag atacaacatt tttatctctt cttaataatt ccaacacttt
    12841 gtcaacttct aagccacatg catctgcaat ctcatctata gttggctctc ttaataatac
    12901 atttaaaagt tcttgtttct ttttctttac aaaatttatt ctctgatgaa gatgtatagg
    12961 tatcctaata gtattttcgc aatcgtcgat atatcttgtt atactttgtt ttatccacca
    13021 agttgcataa gtgctaaatt tgtatccttt tttataatcg tacttttcta cagcttttat
    13081 aagtcctata tttcctgctt gaattaaatc caacatatca atactatctc ttttatatct
    13141 ctttgctatg ctcactacca acctataatt tgaatttata aatttttctt ttgctactga
    13201 agatgagttg attatttcct tagccagctc tacctcttct cctgctgaca acattttgta
    13261 ttcctctatt tcctttaaat acattttcat cgcatttgat acatttgatg aacccacaca
    13321 aatataattt tcataattat tttctttttt agtatccata atcaaacccc ttctattcat
    13381 agaatttgct aaaacaaaaa taaataattt aaacctacat aatctacaat tacataatat
    13441 cccattcttt aaatgaattg ttttgtatat tatgtataca aatttataaa aactatacct
    13501 ataatattat tctacttcta accgcaatat cctccttata tatataattt attttattat
    13561 atgttgttat attcttagtt ttttgaatga tatatgtcta aaaaaagact gtttactaaa
    13621 cagtcttttt ttatatatat gctcaatatt taattttcat gatgatgatt acatccacat
    13681 ccacaatttt tatcatggtg atgatgttct tctaaatctt ttgcctgttg ttccatttca
    13741 tgaaactctt ttaccattat atcataagtt ggaagagctg cctcagtatc gtattcttcc
    13801 cctctccaat cagcgtacat catagcatcc ccattagtta aaaccaatct acctgacata
    13861 gttatattat ccacttcttc taaaaattct atttgttttt gtaaaacttc tccttctaac
    13921 tctacatctt catctaaaca ttgcactatc attacaggtg cataataatc ttcttcatct
    13981 ttaacattta caacaatatc taaaactcct tctgcacctt cttcaaattc tgccaactca
    14041 acatttgtat caatcatatc ttgagggact aataaatctt ctattaaata ttttattact
    14101 ctatctttta ctaattcttt tgacatttat ttttctcctt ccgattctat aacattatca
    14161 taatcatttc tatattatag tatactacat taattgtttt ttcaatctct tacaaaaatt
    14221 atttttttat tatcttcctt atattccctt ttttattaca aagttgtaat cgcattgatt
    14281 taaaaaatag tttatattta gtataataga aatgtagcac atatttttat tcaatatatt
    14341 aataaaaaaa tagattgaaa atgtaatgta tgttaaatct aggaggaata ttatgaagtt
    14401 taaaaaacaa attagttcta ttgttgtgtc tactatgctt gtacttggga gtatgaacct
    14461 ttcttatgca gatggtacaa atgtagttac acttggagct aacttatcag agtctcaaaa
    14521 gcagcaaatg cttaattact ttggagtaaa aaaagaccaa gtcttagttt tagatgtaac
    14581 aaatgcagaa gaaagacagt atttacaagg tgttgcaaca gagggtcaac ttggaaaagt
    14641 tactatctct tgctcatacg ttgaacctac taaaaaagga aatggaatta atgttaaaac
    14701 agcaaactta acttgggtaa ctagttcaat gattgcttca acccttacaa cagctggtct
    14761 tgaagatgca aatgttattg ctgctgctcc atatcctgta agtggtactg gagcattgac
    14821 aggaatcatg aaagcatttg aggatgcttc aggaaagaaa cttgatgaaa ctaagaaaga
    14881 aattgcttct gaagaattgg tagttacagg tgacttagga gatgatatag ggcaagaaaa
    14941 agcaacaggt gtaatgaatg atataaaaac agaaattgta aagaatggta caaaagatac
    15001 caatcaaata gcaaatacaa taaataatgt tgtaaataat tacaatatta ctattacacc
    15061 agaacaaaaa gaacaaatta aaggtgtaat gaaaaaaata gctgaccaaa attatgatta
    15121 caatagcatg aaaaatacac tagataatgt atcagataat gtaaatgaac aattaaagaa
    15181 attaggtgaa agtgttaagg gttctggtat actagatact attggtggat ggtttagtgg
    15241 aataggagac tggttctctg gtttattctc aggcggagat aaaaaagatt tgggaatctt
    15301 aaataacact aatgatgagt ctcttggctc tgatgctgta ataaattcta cagaaggtgt
    15361 tcaaataaat ccacaaaata atactaattc taacaatgat agtgatacaa atagctcaaa
    15421 aaatgatact tcaagtaata atgaaaataa cgatagttct caaacaaatg aaaacaacac
    15481 aacaaataat tcagaaaatc aatcaaataa taatgactca gttggtttct ttgaaaaaat
    15541 aaaaaattgg ctttcaggct tattttagaa attaaacaaa taaaaagaat tgcctaaaat
    15601 ggaaattttc tataaaaggc aattctcttt atttacaata aatttttatt actcactcat
    15661 ttttttagat ttttctatac atgcacatat tgcttttatc acagaagctc taaaaccttc
    15721 ttcttcaagt actttaactg cttctatagt agttccacca ggtgaacata ccatatcttt
    15781 taattcacca ggatgttttc ctgtctcaag taccattttt gcagaaccca taacagcctg
    15841 tgatgcaaac ttatatgctt gtggtcttgg cattcctgca attactgctg catctgctat
    15901 agcttctata aataaaaata catatgctgg tgcagaacca cttgcaccaa ttacagcttc
    15961 tataagatac tctggtacta cctcagtatt tccaaaagaa ttaaatactt ctgtaactgc
    16021 ttctaagtct tcattgttta tatttttatt tatagaaaga gaagacatgg cttcatttac
    16081 aagagctgga gtatttggca tagttctaac tattttttta tcttctccta taattgactc
    16141 tatatccttt atagattttc ctgctgctat tgtaactata attttattgt catctataaa
    16201 gtcttttatc tcttccaaaa tatcatcata tatatctggt ttaacagcta caattactat
    16261 atcagaggtt ctagttactt ccttcgagtc ttttgtagta tttattccaa aatttgcatc
    16321 tattctatcg agagttcctt gactatatgc tgatgctata accatattag gttcaactaa
    16381 ttttgaattt actattcccc ctatcatagc gcttgccata tttcctgcac ctatgaatcc
    16441 aatttttttc actttagtac ctccttattg actaatagta atcgttaaaa tttaagcttc
    16501 tttaactgca tcagactttt caaatggatt tggtatactt actaccaaaa ttttcactac
    16561 cttattagta tagttgaccc aattatgatt gttcttttca ctattatagt gtattgtgtc
    16621 tcctggatac atttctattt gttcatctcc caaaaacact gtaagagtac cctctaatac
    16681 atacacaaat tcctcacctt catgtacgta acaacaaatt tcctcactac tcttacttgg
    16741 aagaatttca attaatcttg gtagcattgt tttttccttt aaactagatg ataaatgata
    16801 atgtataaat gttgagtttt ctacatcaaa tacttctttt tcataacttc ttaatacagc
    16861 tcttttatgc tcttttggct tcataaaaaa gtaagttaat tctacatcta gtacacttgc
    16921 tatttttcct aaggaatctg ttgccacact tgttaatcct ctttcaagtt gtgataaaaa
    16981 accaattgac aagtttgttt tttcactcat atccttcagc gtcatttgct tttgagttct
    17041 gagttgcttt atttttgctc ctatgtcctt attcaaaacc atcaccccta aataatttta
    17101 attttttcat aatataaata caaaaatata aatataggta ctgaacctat ctttatttca
    17161 tttaaaaaaa atttttataa gtattactat aatttatcaa tctttttttg tctacatttt
    17221 tacgattatt tacgatttat ttttcacata tgtatattta atcttgccaa ctaaagatac
    17281 attttttata agcatttact ctttatataa taaaacttaa gttgttcatg tagtcttctt
    17341 ctggtttaat tattaaaatt tcaaattata ttattatttc tacacattat tacatccttt
    17401 agtacaatta taacataatt ttacaattta atgatatcta ttcaatgtct ttttttactc
    17461 tacaacatat tttattttag agtttaatac tatatatatt ttttatatac agccttgtca
    17521 ttttttagat tgtcaagagt tattgaagta ttttatgtag atttatattt tattttctaa
    17581 tttctcattt aacaagaatt gcttatgata aaaaataata tcatctcaa
//
LOCUS       DAMJYN010000077        17551 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.080, whole genome shotgun sequence.
ACCESSION   DAMJYN010000077 DAMJYN010000000
VERSION     DAMJYN010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17551)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17551)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17551
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.080"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            112..858
                     /locus_tag="PC466_002851"
     CDS             112..858
                     /locus_tag="PC466_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HDF2770215.1"
                     /translation="MKIENLSIDDIKRGYIFNDDLNCYSCIKCTKTYEVGEIYKIGNR
                     FFEASKAIELHMELEHSDYLEQLLNSDSKYNTLTENQKQLFQLFISDLPDKEIAKQVG
                     VSTSTIRHQKFIFREKAKQAKLYLALYESVFEDKSNKSSTIIPIHEHARMVDERYVVT
                     EEERKHILDTSFESMNPLKLKVFSSKEKKKVVILSKILEQFERGKKYSEKEVNQILES
                     IYDDFATIRRYLIEYGFMSRNKECTKYWLT"
     gene            920..1594
                     /locus_tag="PC466_002852"
     CDS             920..1594
                     /locus_tag="PC466_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDF2770216.1"
                     /translation="MNDELKSILYNKGVDIVRFVDISEFPINQTQGFSKAILFCIGLS
                     KKFITDIYNNLPTDSDEFLEKEEKVEELADWISKYIQNKGYRAYSQSEKNNLEHGYFE
                     KAYINPEMQSGISPLPHKTIANISGIGFMGKNNLFVTEEYGCAFSMCTVLTDAPISVE
                     RYPLIDSKCLNCNVCVENCPAKAIHGNEWTLPGKRESIIDVSKCFCALRCMMSCPWSL
                     RYANQK"
     gene            1962..3308
                     /locus_tag="PC466_002853"
     CDS             1962..3308
                     /locus_tag="PC466_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 55 protein"
                     /protein_id="HDF2770217.1"
                     /translation="MEIETKTPDWINVLELNSKIDITWKYDVSNMIQDIVSDKSLEGS
                     IIYFPKGNYLFEKGIKISQQITLQGDSYYGGDNQVSNLDKKQSIVGTTNFITRGVSNI
                     SIITLEGTSQCIKNINFYYDSHDIEKIPPKNVSAITEYGETQGLFHFEHLFISGFSGI
                     GIEIPYYSTGNDIIVSSCGLGMRLGEKSMLSSSKIYECKNGMEITTGVSLNNVRIEEI
                     REIGINNKGFGFNLIMNLMVDQCGYCGFMFEKMCYSQITARITKCGQYYKSVDYNTYE
                     NMEDRKEEAYSIFYGDILENCNIVLMNSNIDTLENDSLDEHKIYVIKANETNKVMLTC
                     YAEADELIQCAKGNLLLENGENTYKFYNGEICSVGGVQISDIDEKDLIKIIENTLYID
                     DKGKYLMVPRLKKNTVIYSVLDSIEEINKLHGGIWEQIDVKVLAGESMYYYKKIKD"
     gene            3335..4735
                     /locus_tag="PC466_002854"
     CDS             3335..4735
                     /locus_tag="PC466_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 55 protein"
                     /protein_id="HDF2770218.1"
                     /translation="MEESIIIKDISGWINVLDYGICNDETKDVSSKLQEIIDAAPEDS
                     IIYFPKGKYLFESGVKIKKRLTLCGDSYILANVPKNTAGVTQFTFKGKKNPKSENIAI
                     ITAKSVRHCIKSICFYSDSCDRDMTSNHEPPTDGKPRFHHNVIINYRNISAIVCEDKQ
                     GEPGHYENLFFSGFSGIALDMPNNSTANDITVFTSGLGISTGENSTIANSKVWGCVDG
                     MIISTGTFINGMRVEEIKKVGIKNIGRGLNFITNITIDQCGYCGVWFDSISNVQISGN
                     ITRCGQYYYDVSYDNYLMLDNRVKEAYSLFYGNLLESSNIVLSNTNKDNWEDFKEDKH
                     KVYLVEALETKNVLLTCNIDATDWIVKSEKGNLTYNNMRQTVIFYDGKLSSINGIGIS
                     DEDYGDKVKIKKGNIYINSKDKVIKMHKPEVGDIMSTIIKDENILSAHYGGTWGKIGE
                     KIEFGITVHYYKLIEK"
     gene            4945..6381
                     /locus_tag="PC466_002855"
     CDS             4945..6381
                     /locus_tag="PC466_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 55 protein"
                     /protein_id="HDF2770219.1"
                     /translation="MEGRTGIKDGRWINVVERGIKNDGSYNIGPDLQDIIDEIETDFC
                     VLYFPKGKYLFTSGVKINKEIVLQGDSNSPTETTQFITRGVENMSIITLTGKKQCIKN
                     INFYSDSCEIQVNEEPPTKGNPKYHYEMIINKNEKNVEMNNVSAILYDNSKNMIKGLG
                     HYENIYISGFSGTGIRIPYYSIVNDITVSSCGLGIDTGIDTIISNSRISKCQNGMRIR
                     TGTSINNVRIEKIQKVGLISSQVKDYEGYGSYKINNITIDQCGYCGFLFDSVKGSYFS
                     GIIRRCGQYYYNTDYDTYLSIKDRVEEAYSLFYGNYFTECNIDLVSDNKDNWDDGLEY
                     KHKVYVFKTLQIPKLTLRCNIDAYDYIVKSVHGGGNLMLKNNFNNYIFIDSSSPEVIN
                     GINFNYQKNGNLLRLNNGKLSYKNGKEETAIFRPNYGLIVASTDSECEQIETSYGGKW
                     EKLGSEVIGKETVYYYKHHEPDKTNQIK"
     gene            6725..7669
                     /locus_tag="PC466_002856"
     CDS             6725..7669
                     /locus_tag="PC466_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1848 domain-containing protein"
                     /protein_id="HDF2770220.1"
                     /translation="MIVSVSRRTDIPAFYSKWFFNRLKEGFVYVINPMNPKQVSKIEL
                     NPHTVDCFVFWTKDVTPMLYDLNKLKDYKYYFHYTITSYGKEVETCILDKRKVIDSFK
                     ELSRKIGKERVILRYDPIFLSEKYTVDYHIKAFASLCNQLDGFTEKCIISFIDLYKKT
                     KFNTKALHIKPIEITEIETLSKEISKIAHKHGIILEMCSEEYNLSKFGIGKSKCIDDR
                     LISKIIGCEVEVKKDSTQRDICGCVKSVDIGQYNTCRHYCLYCYANFNYAKVEENCRL
                     YKEDNKLLIDTLRDDAKISIRDMKTIKVDKNKQISIFD"
     gene            7838..8770
                     /locus_tag="PC466_002857"
     CDS             7838..8770
                     /locus_tag="PC466_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HDF2770221.1"
                     /translation="MNLLKKYPIPIASLILSIFTLGNLLQSYSESLRNVIGFIGFILY
                     AIYIVKIILLRKGVKEQLENPLISSTFPTITMATMIFATYIKPLSLELSIMIWSIGIV
                     GHLVLIVLFSKKFLVKFSIKTVFPSWYIVYVGIVAASVTAPAFNQLLIGKIAFWIGFV
                     SYIVLIPVILKRVWIIKEMPEPSLPSIAILAAPGSLLLSGYINSFSDKNNVVLYLLFI
                     LSIVFYIIVLGYLPKLLRLPFYPSFAAFTFPMAISAMGMKLMNGYLTKSGHFISWISY
                     ASKLEEIIATVIILYVLVLFIIYLSKSETTSKAK"
     gene            8875..9342
                     /locus_tag="PC466_002858"
     CDS             8875..9342
                     /locus_tag="PC466_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C_GCAxxG_C_C family protein"
                     /protein_id="HDF2770222.1"
                     /translation="MKTKEEYLKEVRNISEEYFRKGEFFCSEAVLQTINDALGQPLSP
                     EITKLASGFPIGLGKAQCLCGAISGGEMALGIVYGRVHGETMNPKMFEHAKGLHDYIK
                     KEYGATCCRAITKKWDGDNFMSPERKEHCIKITGQVTEWVADKLIEDEKLNIK"
     gene            complement(9586..10440)
                     /locus_tag="PC466_002859"
     CDS             complement(9586..10440)
                     /locus_tag="PC466_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009912760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HDF2770223.1"
                     /translation="MLTIIIALLPVMGWGLMPIVANLKKSSPHEQLLGTSISAFIFST
                     IITLVIHPEITFFSFCISMISGIFWSLGQLMQFKAIQIASVSKVMPISNGSQLTFTTL
                     LAVILFNEWTSSKMLLIGSLSILCIILGILLTNYQTKKSTDKNMLKCVGVVLLSSLFL
                     SLYVVTNQIFLIEGYRIILPQSVGMLITSSIIVKYFSKEIVYRENVLFNLITGILWSI
                     ANLGMFITTNTLGVTISFSISQSCVIVATLGGIIFFKEKKNKKEWLAIFIGIILIMSG
                     VFMLSIIK"
     gene            10606..12570
                     /locus_tag="PC466_002860"
     CDS             10606..12570
                     /locus_tag="PC466_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDF2770224.1"
                     /translation="MLTDMIQNREIKIIKFLLKEGHTTVKAIADDLDVSEKTVSKSLK
                     EVEAVLKKIGLSLIRKPKIGVYIDGDLKKILPYLDNKGSQIPTTREERVIYIYSVLLK
                     SNDYITIQQLSDELYISRGTIERDLSEVEKLLKNEGISIYKKPSKGIKLNISERDKRQ
                     LTAKFIHKFWSRNWYIKQEQESFYQAFEKIQADVNGIFSEDDLSIIIDILRNFSRERK
                     FEFSDYEFQSLVIHLAIAVERIRKGEYIEESLYIGNIENNQMSNTNYLAKQLEEKFSI
                     LLPKSEIGYINLHLVAADQHRDTNELKNTSTNPCETSTNNISNLREIIKNTLYETAYD
                     KDLIDGLTSHVHSSINRLKYGLSIKNPYVNTIKQNFSLSFEQALDLKKVIEFIYDIRI
                     NDDECAYIALHFEAFRERMKELPQNIRVILVCSTGLGSSRLLSARIKKYFPMIKIEKV
                     LSVQELVSSKIDADLVISTIYLELETIPTIVVSPILNESDIRTLERNIQNVSCCTSKK
                     YKSFRNLIFEENILLNIEASNYEDAIKYITDNLIKKGFVKEGIAKSAIERENLSYTSF
                     QSIATPHANPSYIKKSNISVATLKNPITWGNEKVEVIFFISLENDKNLELDEIYEVFY
                     DFIDNKKNINDILSATSTKEVYDLLLEESI"
     gene            12570..13031
                     /locus_tag="PC466_002861"
     CDS             12570..13031
                     /locus_tag="PC466_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2770225.1"
                     /translation="MKISDVLKKEQIVFNLDTNTKEETIKKLSSIFVENGIVDNEEEY
                     VKSVLEREEHSTTGIGNGIAIPHGKSDAVKKSSIIFAKTKHKIEWDALDEKPVDSIFL
                     LAISNIDKDSNHLVLLSKLATKLMDDDNVDALKLANSEQEIINIFSEEGEM"
     gene            13034..13354
                     /locus_tag="PC466_002862"
     CDS             13034..13354
                     /locus_tag="PC466_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HDF2770226.1"
                     /translation="MKRKIIAVTACATGVAHTYMAAQALKKASKKMGHLIKVETQGAT
                     GIDNELTTKDAQIAEVVIFAVDTKVRNAERFEGKEILEVPVNAPIKDAEKVINDALKL
                     IDTK"
     gene            13370..14470
                     /locus_tag="PC466_002863"
     CDS             13370..14470
                     /locus_tag="PC466_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HDF2770227.1"
                     /translation="MLKKIVSELKKHVLTGISYMIPLVIAGAMIMAISRVGGSFYNIP
                     DIWDAKYAESASSIVRLLHDLDGFGGTALGLMFPVIAAFIGFSIADKLAIVPGLVGGM
                     IAKDIGAGFLGALAVGLIAGYTCLFIKNHVKLPKSAASIVPIFIVPVFGTLITVVLIN
                     YVIGIPFATLNTGLENWLNGLSGTNQILMAAIIGAMMAVDLGGPVNKAALTTSLALLT
                     SGIYAPNTAAMVGIVIPPLGLGLATILAKQKYNKQLREAGKSSLIMGLIGVSEGAIPF
                     AVESPLKVIPSCVIGTAIASAMAVGLGSVNATPISGFYGWFTVENWPMYVLSIAVGTV
                     IVAGLVIVLRGNPVIEDDEFEDDDFDEAEWES"
     gene            14590..17190
                     /locus_tag="PC466_002864"
     CDS             14590..17190
                     /locus_tag="PC466_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HDF2770228.1"
                     /translation="MIKAHIVNHTHWDREWYFTSGDALVLSEQLFTDVIDELERNPDV
                     SFVLDGQLSILDDYVQLHKEKIEIIKKLIKEDRLHIGPWFTQTDAFFARGESILRNLM
                     IGIFESKKYGKYMKIGYLPDTFGFNAQMPILLKHVGLDNIFFWRGIHLGKHVQSPYFK
                     WKSLNGESYIYAVNMPHGYGTGMLLEPSLKYVNGRLDPAIDFIKSYTDVDEVLIPSGN
                     DQLNIIGDFKNKIKAINDIGKYSYITSSYQEFLKYIKSIESLESYRGEFREPVLARIH
                     KSIGSSRMDIKLACDKLENKLIKRIEPLLVIAKKSKIEISNQLLINTWKKLLEGQAHD
                     SLAGCVTDTVTDYILHRIREANEICDSIENTIVKKISEGLKLSKNDILVFNTEAKRFN
                     GYKEIQVVSDSKNIYFKDNLDATIIEETYVKPRENVLEETPAGNVFIEESGYYILKVR
                     INVQLPALGYKVVSFESSDKEMVSLDKSNDTFISNDNYKIIYEDGSLNLQLKDGTYIS
                     NFLILKDSGNAGDTYDFSPLKNDEDIKLSFDRVYTEKTLGYEKLVVKGTTLLPLTLED
                     RKNKYLNGKLNVKVSIVLSKENPLMDVKLCVDNTIYNHRLRVHIKTDIKDNKNIASLP
                     FGYITRENGVLDNWEDIYSEMPIDLEPLESNITLTNQNRSCTVFTRGIKEYQHIEDEI
                     ALTLLATTDELGKPDLLYRPGRASGDTTKKGHIRIKTDKAQMLKKLEFSFAIYMDSKS
                     FDELEIANLTHNYLRECVNYQLQDYNFFLYRIDNKIQKSIVNKTVSRELEIISLPEKY
                     LISACYPSYYSKDKFIIRVENPSSNRMILDEQIFKNRNGKIVNAIEDVEEEQVYEIAP
                     FDVISILLDL"
BASE COUNT         6999 a         1795 c         3020 g         5737 t
ORIGIN      
        1 attaataaat aattagaatt gataaacaaa aaataaaaat gttgattata ttaataaact
       61 ttaatataat atatttatga aaaatgtaaa ttgtgaaatg gaggtagtaa catgaaaatt
      121 gaaaatcttt ctattgatga tattaaacga ggctatatat ttaatgatga tttaaattgt
      181 tatagttgca ttaaatgtac aaaaacatat gaggtaggag aaatatataa aataggtaat
      241 agattctttg aagcttcaaa agctattgaa cttcatatgg aattagaaca tagtgattat
      301 ttagagcaat tgcttaatag tgattcaaag tacaacacat tgactgaaaa tcaaaaacaa
      361 ttatttcaat tatttattag tgatttacca gataaggaga tagcaaaaca ggttggagta
      421 tccacatcta ctatacgcca tcaaaaattt attttcagag aaaaagcaaa acaggctaag
      481 ctctatttag cactatatga atctgtattt gaagataaat ctaataaaag tagtactata
      541 ataccaatcc atgaacatgc tcgaatggta gatgaaagat atgtagtaac tgaagaagag
      601 agaaaacaca ttttggatac atcatttgaa agtatgaatc ctttaaaatt aaaagtattt
      661 tcttcaaaag aaaagaaaaa ggtcgtaatt ttatctaaga ttttggaaca atttgaacgt
      721 gggaagaaat attcagaaaa ggaagttaat cagattttag aatctatata tgatgatttt
      781 gcaacaatta gaagatattt aattgagtat ggctttatga gtagaaataa agaatgtaca
      841 aagtattggt taacataatt aaaataataa attttactaa tgtgtaatgt tatttttatc
      901 taggggggag gagttaaata tgaatgatga attaaaatct attttataca ataaaggtgt
      961 agacattgtt cgctttgttg atatatctga atttccaata aatcaaacac aaggtttttc
     1021 taaagcaatt ttattttgta tagggttatc aaaaaaattt attacagata tatacaataa
     1081 cttacctaca gatagtgatg agtttttgga aaaagaggag aaagtagaag aattagctga
     1141 ctggatttca aaatatattc aaaataaagg atatagagcg tattctcaat cggagaaaaa
     1201 caatctagaa catggatatt ttgaaaaagc ctatattaat ccagaaatgc aatcagggat
     1261 tagtccttta ccacataaga caatagcaaa tattagtggc attggattta tgggaaaaaa
     1321 taatttgttt gtaacagagg aatacggatg tgcttttagc atgtgtacag tacttacaga
     1381 tgctccaatt tctgttgaaa gatatccttt gattgattca aaatgtttaa attgtaatgt
     1441 ttgtgtagag aactgtcctg caaaagctat acatggaaat gaatggactt tacctggaaa
     1501 aagagaatct attattgatg tttcaaagtg tttttgtgca ttgaggtgta tgatgagttg
     1561 cccatggtca ttaagatatg caaatcaaaa ataactttac tagagaaggt attaaattga
     1621 atattataaa atttttaaaa tgtaagatta tataagattt ctcaaaataa aaatttgtat
     1681 agaacactca gaaatgagtg tttttctatt gggattaaat tatattgata caaagcttaa
     1741 ctattttaat cattatataa aatttgtatt aaaaaattaa gaataacttg ctaatagtaa
     1801 aaatataatg agattataat tgatttataa tataactgta atgatgttgt aaaatgaaaa
     1861 ttgtcatctc aaaattccca aaaagagtaa aagtcacttc ggttatagtc aaaaaatttt
     1921 ttctgtgaaa agaatttaga tttaaaaggg aggaattaat catggaaatt gaaactaaaa
     1981 ctccagattg gattaatgta ctagaattaa acagtaaaat agatattact tggaaatatg
     2041 atgtaagtaa tatgatacaa gatattgtct ctgataagtc actagaaggt tccattatat
     2101 attttccaaa aggtaattac ttatttgaga aaggtattaa aattagtcaa caaataacac
     2161 ttcaaggaga ttcttattat ggaggagata atcaagtatc aaatttagat aaaaaacaat
     2221 caatcgtagg aacaaccaat tttataaccc gaggagtttc taatataagt attattacat
     2281 tggaaggaac aagtcaatgt atcaaaaata ttaattttta ttatgatagt catgatatag
     2341 agaaaatacc acctaaaaat gtatctgcta ttacagaata tggagaaaca caaggactat
     2401 ttcactttga acacctgttt atttctggat tttcaggaat agggattgaa attccatact
     2461 attcaactgg caatgatatc attgttagtt catgtggtct tggtatgagg cttggagaga
     2521 agtcaatgct ttctagtagc aagatttatg aatgtaaaaa tggaatggag attactactg
     2581 gtgttagctt aaataatgtg agaatagaag aaataagaga aataggtatt aataataaag
     2641 gatttggttt taacctgatt atgaatctta tggtcgacca atgtggatat tgtggattta
     2701 tgtttgaaaa aatgtgttat agccagataa ctgccagaat tactaaatgc ggtcagtatt
     2761 ataaaagtgt tgattataat acttatgaga atatggaaga tagaaaagaa gaagcttatt
     2821 ccatttttta tggagatatt ttagaaaatt gcaatattgt attgatgaat agtaatattg
     2881 ataccttaga aaatgattca cttgatgaac ataagatata tgtaatcaag gcaaatgaaa
     2941 caaacaaagt aatgttaaca tgttatgctg aagcagatga gcttatacag tgcgcaaagg
     3001 gcaacttgtt gctagaaaat ggtgaaaata cttataaatt ttataatggt gagatttgtt
     3061 ctgtaggagg tgttcaaatt tctgatatag atgaaaaaga tttaatcaaa ataatcgaga
     3121 acactctgta tatagatgat aaaggtaagt acttaatggt tcctagatta aaaaagaata
     3181 ctgtaatata ttcagtacta gattctatag aagaaataaa taaattacat ggtggaatat
     3241 gggaacagat tgatgtaaaa gtattagctg gggaatctat gtactattat aaaaagataa
     3301 aagattaaat tatcaaacta ggaggtagtg attaatggaa gagtctataa taattaaaga
     3361 tataagtggc tggattaatg tacttgatta tgggatttgt aatgatgaaa caaaagatgt
     3421 aagttccaag ttgcaagaga ttatagatgc tgcaccagaa gattctatta tatattttcc
     3481 aaaaggaaaa tacttatttg aaagtggtgt taagattaag aaacgattaa ccttatgtgg
     3541 agattcttat attttggcga atgttcctaa aaacactgct ggagtaacac aatttacttt
     3601 taaaggaaag aaaaatccta aaagtgaaaa tatagcaatt ataacagcaa aaagtgtaag
     3661 acactgtatt aagagcattt gcttttattc agatagttgt gatagagata tgacatctaa
     3721 tcatgaacct ccaacagatg gaaaacctag atttcatcat aatgtaatta taaattatag
     3781 aaatatatcg gctattgtat gtgaagataa acagggagaa ccaggtcatt atgaaaactt
     3841 gttttttagt ggtttttctg gaattgcact tgatatgcct aataattcta cagcaaatga
     3901 tattacagtt tttacatccg gacttggaat tagtacaggg gaaaattcaa cgattgctaa
     3961 cagtaaggtt tggggctgtg ttgatggaat gataatttct actggaactt ttataaatgg
     4021 tatgagggta gaagaaataa aaaaagttgg aattaaaaat attggtagag gtttaaattt
     4081 tattacaaat atcacaattg accaatgtgg atattgtgga gtttggtttg attctatatc
     4141 caatgttcag atatcaggaa atatcacaag gtgcggacag tactattatg atgtaagcta
     4201 tgataattat ttaatgttgg ataatagagt taaagaagca tattctttat tctatggtaa
     4261 tttattggag tcaagtaata tagttttgtc aaataccaat aaagataatt gggaagattt
     4321 caaagaggat aagcataagg tgtatcttgt agaagcactt gaaaccaaga atgtactatt
     4381 aacatgcaat atagatgcta ctgactggat tgttaagtca gaaaaaggaa atttaacgta
     4441 caataatatg cgacaaactg ttatatttta cgatggaaaa ctaagtagta tcaatggaat
     4501 tggtatatct gatgaagatt atggggataa agtcaagata aaaaaaggaa atatatatat
     4561 aaatagtaag gataaggtta ttaagatgca taaaccagag gtaggtgaca ttatgtcaac
     4621 aattattaaa gatgaaaata tactttccgc tcattatggg ggaacatggg ggaaaattgg
     4681 tgaaaaaata gagtttggaa taactgtaca ctattataaa ttgatagaga aataagtaaa
     4741 tacgtagtat ttgaatagat gtattttatt ggagagctag gactatagtt ttaatgtaaa
     4801 tggtttggta atagcatgga ttgaataata taaaaataat ataaaaaatt aatttgatta
     4861 tgtaaaattc tatgaagtag taaacctgtg actttagtca tggtaggttc aaattaagta
     4921 aatgggaaag gaatatataa tattatggaa ggaagaactg ggattaaaga tggaagatgg
     4981 attaatgtag tagaaagagg tattaaaaat gatggttcgt acaacatagg tcctgattta
     5041 caggatatta ttgatgaaat agaaacagat ttctgtgtct tatattttcc aaaaggaaaa
     5101 tacttattta caagtggtgt taaaattaat aaagaaattg tattacaagg tgattctaat
     5161 tcacctacag agactacaca atttataact cgtggagtag aaaatatgag tattattaca
     5221 ttgacaggga agaaacaatg tattaaaaat ataaatttct attctgatag ttgtgagata
     5281 caggtaaatg aagaaccacc gacaaaaggt aatcctaaat atcattatga gatgattatt
     5341 aataagaatg aaaaaaatgt tgagatgaat aatgtatcag caattctgta tgataatagt
     5401 aagaatatga ttaaaggtct aggtcattat gaaaatattt atataagtgg tttttcgggt
     5461 acaggaatta ggataccata ttactcaatt gtaaatgata ttacagtttc atcttgtggg
     5521 ttgggtattg atacaggaat agacacaatt atttctaata gtagaatatc taagtgtcaa
     5581 aatggaatga ggattagaac tggaactagc ataaataatg taagaattga aaaaatacag
     5641 aaagttggtc ttataagtag tcaagttaag gattatgagg gatatggaag ttataaaatt
     5701 aataatatta cgattgacca atgtgggtat tgtggttttt tatttgactc agtgaaaggt
     5761 agttattttt ctggtattat aagaagatgt gggcagtatt attataatac agattatgac
     5821 acatatttaa gtattaaaga tagagtagaa gaagcatatt ctttatttta tggaaattat
     5881 tttacagaat gtaatattga tttagttagt gataataagg ataactggga tgatggctta
     5941 gaatataaac ataaagttta tgtatttaaa acccttcaaa taccaaaatt aacattgaga
     6001 tgcaatatag atgcctatga ttatatcgtt aaatcggtac atggaggagg taatttaatg
     6061 ttaaaaaata actttaacaa ttatatattt attgattcat ctagtccaga agttattaat
     6121 ggaattaatt ttaattatca aaagaatgga aacctgttaa ggttaaataa tggtaaatta
     6181 agttataaaa atggaaagga agaaacagct atattcagac ctaattatgg tcttattgta
     6241 gcatcaacag attcagaatg tgaacaaata gagactagct atggaggaaa atgggagaag
     6301 cttggttctg aagtaattgg aaaagaaacg gtatattatt ataaacatca tgaaccagat
     6361 aaaacaaacc aaataaaata aaatttgtat tatataatga tataaagttt taatatatag
     6421 tgtttacctt taatgtaata ttggtatatt tgtatagtat taaatttgtt aaaaagtaaa
     6481 attgtagggt gcttgaaaat agcacctttt ttagtttcat tataaaatta gttttgaaag
     6541 tttaggaata atgtatattt atttttaaag aattataacc ttattaagga tattttaaat
     6601 gctagaaatg aatcagtaaa tcatactgga attatcttaa atgttttgat taaattaagt
     6661 atttagagct ataattatat taaaaatata ttaggacata attatattac tatggaggtt
     6721 aaatatgata gtaagtgtga gtagaagaac tgatatacct gctttctata gtaagtggtt
     6781 ttttaacaga cttaaagaag gttttgttta tgtaattaat ccaatgaatc caaaacaggt
     6841 tagtaagata gagttaaatc cacatactgt tgattgtttt gtattttgga caaaggatgt
     6901 aactccaatg ttatatgatt taaataaatt aaaagactat aaatattatt ttcactatac
     6961 tataacatca tatggaaaag aagtagagac atgtatttta gataaaagaa aggtaataga
     7021 ttcatttaag gaattgtcta gaaaaatagg caaagaaaga gtaattttaa gatacgaccc
     7081 gattttctta agtgaaaagt acacagtaga ttatcatatc aaagcatttg cgagtttatg
     7141 taatcagctt gatggattta cagaaaaatg tataataagt tttatcgatt tatataagaa
     7201 aacaaaattt aatactaaag cattacatat aaagccaata gaaattacag aaatagaaac
     7261 attatcaaaa gaaatttcta agattgctca taagcatggg ataatacttg aaatgtgttc
     7321 tgaagaatat aatttaagta aatttgggat tggaaaaagt aagtgtattg atgatagatt
     7381 aatatcaaaa attataggat gtgaagtaga ggtaaaaaaa gatagtacac aaagagatat
     7441 ttgtggatgt gttaaaagtg tcgatatagg acaatacaat acttgcagac attattgtct
     7501 gtattgttat gctaacttta attatgcaaa agtagaagaa aactgtaggc tttataaaga
     7561 agataataaa ttactcatag atactttaag agatgatgca aaaataagca ttagagatat
     7621 gaagactatt aaagtagata agaataaaca aattagtata tttgattaaa ataaatatac
     7681 taattacctt aatatatcaa gaatatagat acttttgata acaaaattaa acttaataga
     7741 tattttctat ataagaaaga tggtcataat atgtcaattt gaccatcttt ttgatataat
     7801 taaaacacaa ataatttagt aacaaaggag gcagaacttg aatttattaa aaaaatatcc
     7861 tatacctatt gcaagtttga ttttgtcaat ttttacttta ggtaacttat tacaatctta
     7921 tagtgaatca ttacgtaatg taattggatt tataggattt attttgtatg caatttatat
     7981 agtcaaaata atattactta gaaagggtgt taaagagcaa ttagagaacc ctttaatatc
     8041 aagtacattt ccaactataa caatggcaac aatgatattt gctacatata taaaaccatt
     8101 atctttagaa ttaagtatta tgatttggag cataggaatt gtgggtcatc ttgtgttaat
     8161 agttttattt agtaagaagt tcttagttaa attctcaata aaaacggtat ttccatcttg
     8221 gtatatagta tatgttggga tagttgcagc tagtgttacg gcaccagcat ttaatcaact
     8281 tttgattggc aaaattgctt tttggatagg atttgtatct tatatagttc ttataccagt
     8341 aattttaaag agagtatgga taatcaagga aatgcctgaa ccatctttac caagtatagc
     8401 tatattagct gcaccagggt cactattatt gtctggatat attaattctt tttcagataa
     8461 aaataatgta gtattatact tgttattcat attatcaatt gtattttata ttatagtttt
     8521 gggatactta ccgaaattat taagattgcc tttttatccg agttttgctg catttacatt
     8581 ccctatggca ataagtgcaa tgggtatgaa actaatgaat ggttatttaa ctaaatcagg
     8641 tcattttata agttggattt catatgcttc taagttagaa gagataattg ctacagtgat
     8701 tattttatat gttttagttt tatttattat atatcttagt aaatctgaaa ctacatctaa
     8761 agctaaataa gaattattaa atatgtgtat ttaataggaa tattgatata aatatatgaa
     8821 gataagataa accatagaaa cttaatttag cttaatttta ttggaggaaa acaaatgaaa
     8881 acaaaagaag aatatttaaa agaagttaga aacatatcag aagaatactt tagaaaagga
     8941 gagttttttt gctctgaagc agttcttcag acaataaatg atgctttagg ccaaccttta
     9001 agtccagaga taactaaatt agcatcagga tttccgatag gacttggaaa agctcaatgc
     9061 ctttgtggag cgatatctgg aggagagatg gctttaggta tagtatatgg aagagtacat
     9121 ggagaaacta tgaatccaaa gatgtttgag catgctaaag gtttgcatga ttatattaaa
     9181 aaagagtatg gtgcaacatg ttgtagagct attacaaaga aatgggatgg tgataacttt
     9241 atgtctcccg aaagaaaaga gcactgtatt aaaataacag gtcaagttac agagtgggtt
     9301 gcagataagc ttatagaaga tgaaaaactt aatatcaaat agtgtaatat tagttggtga
     9361 atttataaag ttaaatttac ttatagtata agatacttga tattctcgta ttgatagaaa
     9421 aatttatagc atatgtattt aatgaaatat acttatattt agagtgtggt ttaatttcat
     9481 aaatacatat gctattattt taagtatata agcaaattta tttaaataaa tagaaacagt
     9541 taatttatat gtacaaaact atatatgatt agtgtaaata aatacctatt ttataatact
     9601 caacataaag acaccagaca tgattagtat tataccaata aaaatagcaa gccattcttt
     9661 tttgttcttc ttttctttaa aaaatataat ccctcctaaa gtggctacta tcacacaact
     9721 ctgagagata gaaaaactta ttgtaactcc caatgtatta gtcgttatga acatacctaa
     9781 atttgctatt gaccacaata taccagtaat taaattgaat aaaacatttt ccctatatac
     9841 aatctcttta gaaaaatact tgacaataat agatgaagtt atcaacatac caacagattg
     9901 aggtaatata attctatatc cttcaattaa aaatatttga ttagttacaa catataatga
     9961 taaaaataga gatgataata atacaactcc aacacatttt aacatatttt tatctgtaga
    10021 ttttttagtt tgataattag tgagaagtat accaagtatt atacataata ttgataaaga
    10081 accaatcagt aacattttag aactggtcca ttcattaaac aagattacag ctaataatgt
    10141 cgtaaaagtt aattgtgaac catttgaaat tggcattact ttagatacac tagcaatttg
    10201 aattgcttta aactgcatta attgtcccaa actccagaat atgccagaaa tcatacttat
    10261 acaaaatgaa aaaaatgtaa tttcaggatg tataaccaga gttattatag tggaaaatat
    10321 aaacgcactt atggatgtac ctaaaagctg ttcatgagga gaacttttct ttagatttgc
    10381 aactatgggc atcaatcccc atcccattac aggaagtaaa gcaataatta ttgtcagcat
    10441 taaactattt cctttcatat taaatttaga cagcttttaa tttatcatct aaaattaaag
    10501 tgttcaatac ataaaaatta ccgtatttaa tcaggaaata ttagtagttt tttagaaaaa
    10561 cattttccat taaaataaag ataaagggaa ggagtaaaat tgaaaatgtt aactgatatg
    10621 attcaaaatc gtgaaattaa aataataaag tttttattaa aagaaggtca tacaactgta
    10681 aaagcaatag cagatgattt agatgtttca gaaaaaacag tttcaaaatc tcttaaagaa
    10741 gtagaagcag tgcttaaaaa gataggtctt tctttaataa gaaaacctaa gataggtgtt
    10801 tatattgatg gagatttaaa aaaaatactt ccttacctag ataataaagg aagtcaaatt
    10861 cctacaacca gagaggagag agttatctat atatattcag tacttttaaa gagtaatgat
    10921 tatattacta tacaacaact ttctgatgaa ctatatataa gtcgtggaac tattgaaagg
    10981 gatttatcag aagttgaaaa actgctaaaa aacgaaggga tttccatata taagaaacct
    11041 agtaagggaa taaagttaaa tataagtgaa agagataaaa gacaacttac tgctaagttt
    11101 atacataaat tttggagtag aaactggtat attaagcaag agcaagaaag cttttatcaa
    11161 gcatttgaaa agatacaggc agatgtaaat ggtatttttt cggaagatga tttatcaata
    11221 attattgata ttcttaggaa tttcagcaga gaaagaaaat ttgagttctc tgattatgaa
    11281 tttcagtcat tagttattca tttggcaata gctgtagaga gaattagaaa aggcgaatat
    11341 atagaagaaa gtttgtatat tggtaatata gaaaataatc aaatgtcaaa taccaattat
    11401 ttagcaaaac aattagaaga aaaattttca atattattac caaaatctga aattggatat
    11461 ataaatttac atttagtagc ggctgaccaa catagagata ctaatgaact aaaaaatact
    11521 tcaactaatc cttgtgaaac aagtacaaat aatatatcaa atcttcggga aattataaaa
    11581 aatacattgt atgagacagc ttatgacaag gatttaattg atggattgac ttcacatgta
    11641 cattcatcaa taaatagact gaaatatgga cttagtatta aaaacccata tgtaaataca
    11701 atcaaacaaa acttttcttt atcatttgag caagctttag atttaaagaa agtaattgaa
    11761 tttatatatg atattagaat aaatgatgat gaatgtgctt atatagcatt acattttgaa
    11821 gcttttagag aaagaatgaa agaacttcca caaaatatta gagtaattct agtatgcagt
    11881 acaggattag gttcatctag gttattgtct gcaagaataa aaaaatactt tccaatgata
    11941 aagattgaaa aagtactttc cgtacaagaa ttagtatcca gtaaaattga tgcagattta
    12001 gtaataagta ctatttattt agagttagaa acaattccaa ccatagtagt tagccctatt
    12061 ttaaatgaaa gtgatataag aaccttggaa agaaatatac aaaatgtttc atgttgtact
    12121 tctaagaagt ataaatcttt cagaaaccta atctttgaag aaaatatatt gttaaatatt
    12181 gaagcttcaa actatgaaga tgcaattaag tatataacag ataacctaat aaaaaaaggt
    12241 tttgtaaaag aaggtatagc taaaagtgca attgagagag aaaatttatc ttacacgtct
    12301 tttcagtcaa tagctacacc tcatgctaat cctagttata ttaaaaaatc taatatatct
    12361 gttgcaacgt taaaaaatcc tattacatgg ggaaatgaaa aggtggaagt tattttcttt
    12421 atttcattag aaaatgacaa aaacctagag cttgatgaaa tatatgaagt tttttatgac
    12481 tttattgaca ataaaaaaaa tataaatgac atattaagtg caacttccac aaaggaagtg
    12541 tacgatttgc tattggagga gagtatatag tgaaaatatc agatgtattg aaaaaagagc
    12601 aaattgtttt taatcttgat acaaatacaa aggaagaaac aataaaaaaa ttaagtagta
    12661 tatttgttga aaatgggatt gtggacaatg aagaagaata tgttaagtct gttttggaaa
    12721 gagaagaaca ttcaactaca ggtattggta atggtattgc tattcctcat ggaaaaagtg
    12781 atgctgtcaa aaaatcttct ataatatttg caaagactaa gcataagatt gagtgggatg
    12841 ctttagatga aaaaccagta gatagtattt tcttattggc tataagcaat attgataagg
    12901 atagcaatca tcttgtacta ttatctaaat tagcaactaa acttatggat gatgacaatg
    12961 tagatgcact aaaattagcc aattcagaac aagaaataat caatatattt agtgaagaag
    13021 gagagatgta gaaatgaaaa gaaaaattat agcagttaca gcatgtgcaa caggagttgc
    13081 acatacatat atggcagctc aagcgttaaa gaaagcttca aaaaagatgg gtcaccttat
    13141 aaaagttgaa acacaaggag ctacaggaat cgataatgag ttaactacaa aggatgcaca
    13201 aattgcagaa gtagtaatat ttgcagtaga tactaaagtc agaaatgctg aacgttttga
    13261 gggaaaagaa atactagaag taccagttaa tgcacctata aaggatgcag agaaagtaat
    13321 aaatgatgca ttaaagttaa ttgacactaa ataaatggag ggaaatgtaa tgttgaaaaa
    13381 gatagtctct gagttaaaaa agcatgtctt aactggaatc tcatatatga ttccattagt
    13441 aattgcaggt gctatgataa tggcaatatc tcgtgtaggt ggttctttct ataatatacc
    13501 agatatatgg gatgctaaat acgcagaaag tgctagtagt attgttagat tattacatga
    13561 tctagatgga tttggaggta ctgcattagg attaatgttt cctgtaattg ctgcatttat
    13621 aggattttct atagctgata aattagctat tgtaccaggt cttgttggag gtatgattgc
    13681 taaagatata ggtgcaggat ttttaggagc tttggcagtt ggtcttatag caggatatac
    13741 atgtttgttt attaaaaatc atgttaaatt accaaaatca gcagcttcaa tagtaccaat
    13801 atttatagta ccagtatttg gaacattaat cactgttgta ttaatcaatt atgtgatagg
    13861 tatacctttt gccacattaa atactggatt agaaaattgg ttaaatggat tatctggtac
    13921 aaatcagata ttaatggcag ctattatagg ggctatgatg gcagttgact taggtggacc
    13981 agttaataaa gcagctttaa caacatcact tgcattatta acaagtggaa tttatgcacc
    14041 taatactgct gcaatggtag gaatagttat accaccacta ggattgggac ttgctactat
    14101 actagcaaaa caaaaatata ataaacagtt acgtgaagct gggaaatcat ctcttataat
    14161 gggtttaatt ggagtaagtg aaggagcaat tccttttgcg gtagaatctc cattaaaagt
    14221 aataccttca tgtgtaattg gaacagcaat tgcttcagct atggcagttg gtttaggttc
    14281 agtaaatgca actccaatta gtggatttta tggatggttt acagtagaga attggccaat
    14341 gtatgtgtta tcaatagcag ttggaacagt aattgtagct ggattagtta tagtattgcg
    14401 tggaaatcca gtgattgagg atgatgaatt tgaagatgat gattttgatg aagcagagtg
    14461 ggaatcttaa aatttaataa ctatttaaga cgtgttataa gctatattca atatgaatct
    14521 tatactaaat aaagtgttaa atattcagtt tagacttaaa tataaaagat aaagaacaga
    14581 ggagaataaa tgataaaagc acatattgtt aatcatacac actgggatag agaatggtat
    14641 tttacttctg gagatgcatt agtacttagt gaacaactat ttacagatgt aattgatgaa
    14701 ttagaacgta atccagatgt aagttttgta cttgatggac aactttctat tttggatgat
    14761 tatgtacaat tacacaaaga aaaaatagaa atcattaaaa agttaataaa agaagataga
    14821 ctacatattg gaccatggtt tactcaaact gatgcattct ttgctagagg agagtctatt
    14881 ttaagaaact taatgattgg aatttttgaa agtaaaaagt atggtaagta tatgaaaatt
    14941 gggtatttgc cagatacatt tggatttaat gcacagatgc ctatactatt aaagcatgta
    15001 ggtcttgata atatattctt ttggagaggt atacatcttg gtaaacatgt tcaatcacca
    15061 tattttaagt ggaaaagctt aaatggagaa agttatatat atgcagtaaa tatgccacat
    15121 ggatatggaa ctggtatgct tttagagcct tcattaaagt atgttaatgg acgcttagac
    15181 ccagctattg attttattaa atcatatact gatgtagatg aggtgttaat accttctggg
    15241 aatgaccagt taaatataat aggtgatttc aaaaataaaa ttaaagcgat taatgatatc
    15301 ggaaagtatt catatataac gagttcatat caagagtttt taaaatatat aaagtccata
    15361 gaatcactag aaagctatag aggtgaattt agagaacctg tattagcaag aatacataaa
    15421 tcaattggtt ctagtagaat ggatataaaa ttagcatgtg ataaactaga aaacaagctg
    15481 attaaaagaa tagagccatt attagtaatt gctaaaaaga gtaaaattga aataagcaat
    15541 cagttactta taaatacatg gaaaaaactt ttggaaggac aagcacacga tagtctagct
    15601 ggatgtgtaa ctgatactgt aacagattat attcttcacc gtataagaga agcaaatgaa
    15661 atatgtgaca gtattgaaaa tactattgta aaaaagattt cagaagggct taaattatct
    15721 aaaaatgata ttttagtatt taatacagaa gctaagcgtt ttaatggata taaagagata
    15781 caagttgtaa gtgatagtaa aaatatttat tttaaagata atttagatgc tactataatt
    15841 gaagaaactt atgtaaaacc gagagaaaat gtattagaag aaacacctgc tggcaacgta
    15901 tttattgaag aatcaggata ttatatatta aaagtaagaa taaatgtaca gcttcctgca
    15961 cttggttata aagttgttag ttttgaatca agtgataaag aaatggtatc acttgataaa
    16021 tctaatgaca cttttatatc taatgataat tataagataa tctatgaaga tggaagctta
    16081 aatttacaac ttaaagatgg aacttacata tcaaactttt taatattaaa agatagtggt
    16141 aatgcaggcg atacctatga cttttctcca ttaaaaaatg acgaggatat aaaactttca
    16201 tttgatagag tgtatacaga aaaaacttta ggatatgaaa agttggtggt taaaggtact
    16261 actttactac cacttacatt agaagataga aaaaacaaat atcttaatgg gaaattaaat
    16321 gtaaaagtaa gtattgtctt atccaaagaa aatccattga tggatgtaaa actttgtgtt
    16381 gataacacga tatataatca tagactacgt gttcatataa aaactgatat aaaagataat
    16441 aaaaacatag catcattgcc atttggatat ataacaagag aaaatggagt tttagacaac
    16501 tgggaagata tttacagtga aatgcctata gatttagaac ctttggaaag taatattact
    16561 ctaacaaacc aaaatagaag ctgtactgta tttactagag gaataaaaga gtatcaacat
    16621 attgaagatg aaattgcatt gaccttactt gctactacag atgaactagg aaagcctgat
    16681 ttattatata gaccaggacg tgcttctggt gatacaacta aaaaaggtca tataagaatt
    16741 aaaacagata aagctcaaat gcttaagaaa ttagaatttt catttgcaat atatatggat
    16801 tctaaatcat ttgatgaatt ggaaattgcg aatttaaccc acaattatct aagggaatgt
    16861 gtaaattatc aattacagga ttacaatttc tttttatatc gtatagataa taagattcaa
    16921 aaatcaattg tcaataaaac tgtaagtaga gaattagaaa taatatcttt accagaaaaa
    16981 tatcttatat cagcatgtta tccttcttat tacagtaaag ataaatttat aataagagtg
    17041 gaaaatccaa gtagtaatag aatgatattg gatgagcaaa tatttaaaaa tagaaatggg
    17101 aaaattgtaa atgcaataga agatgtagaa gaagaacagg tatatgaaat agcacctttt
    17161 gacgttattt caatattatt ggatttataa gtgtaaaagt aagtttattg tttaaagtct
    17221 gacagatatt aatctgccag actttttaat ttgtataaat ttgggtaaat attaatgaat
    17281 agttttagta tttaaatatg aatttagtat ttaatataga atttattgaa gtagaataat
    17341 tagtttaaca ggataagcag tttaaataaa gaattattat attagagtga ttttatatat
    17401 aatttaaaat aataaaatgt taataaaatg agttaaagat tgtatattaa tagggttgat
    17461 gtagttacaa aaaagttacc aattgttatg tatttacaaa actgatatat taattacata
    17521 aaatctaaaa tagtttgtaa taggagtata t
//
LOCUS       DAMJYN010000078        17138 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.081, whole genome shotgun sequence.
ACCESSION   DAMJYN010000078 DAMJYN010000000
VERSION     DAMJYN010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17138)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17138)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17138
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.081"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(214..738)
                     /locus_tag="PC466_002865"
     CDS             complement(214..738)
                     /locus_tag="PC466_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HDF2770229.1"
                     /translation="MENKNPIVTIEMENGKEIKIELYPNIAPNTVKNFVSLVNEGYYN
                     GIIFHRVIPGFMIQGGCPNGTGMGGPGHSIKGEFSGNGFTNNLKHERGVISMARTMAP
                     NSAGSQFFIMHKNSPHLDGQYAGFGRVIEGMDTVDEIASVRTDSADKPQTPQIMKSVT
                     VETFGIDYSDVEKN"
     gene            complement(803..1555)
                     /locus_tag="PC466_002866"
     CDS             complement(803..1555)
                     /locus_tag="PC466_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HDF2770230.1"
                     /translation="MKLGLCLEGGGAKGAYQAGVVKALYDGGINKFYSISGTSIGAIN
                     GYYLYTGNVDNLEKMWTNIKDIQNGNVKIVNNTVDNSPAIDNLRELDDSNIEEMNFYV
                     NYVEVDNKVVSEKIVDISKMPRNEAIISISYSGLLPSNPNATLGFKEQFVKDVQEGIY
                     DGFKLDGGLIRSALIEPLIGDNVDKIILISTKYNYELPEDIKKVYDEDKIIVVRPNTQ
                     FAPKDTLNFDDEFCKTIYQEGYEIGKNILDRL"
     gene            complement(1586..2884)
                     /locus_tag="PC466_002867"
     CDS             complement(1586..2884)
                     /locus_tag="PC466_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M18 family aminopeptidase"
                     /protein_id="HDF2770231.1"
                     /translation="MDSINFAKNLIDFIYDSPSSFHAVESTKEILDKNGFEELVLNQR
                     WNLRVGGKYYVTKNLSAIVAFVVNSEDIERDGFRIIGSHSDSPTFSIKPNAEIEAEKS
                     YLKLNTECYGGAILSTWLDRPLGIAGRVVLKGDSILKPNERLIDFKKPICIIPNLAIH
                     LNRSINDGHSYNKQKDMLPLVGMLNDTLEKDNFLIKQIASNLDVNMEDIIDFDLFLYE
                     FEKGSLIGANDEFISIGRQDNLAMVHASLNALVNTKGQQGVNVMAVFDNEEVGSSTKQ
                     GADSNMLLNILERICISMGKDREGFFESIYSSFMISSDLAHAIHPNIPEKHDPTNKPI
                     MGKGPVIKINASQAYTSDGYSIAIYKNICREVNVEYQEFVNRSDERGGSTIGPISSTH
                     IDIPSVDVGSPILAMHSIRELGNVEDHYSIYKTFSKFFEI"
     gene            complement(2901..5165)
                     /locus_tag="PC466_002868"
     CDS             complement(2901..5165)
                     /locus_tag="PC466_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3553 domain-containing protein"
                     /protein_id="HDF2770232.1"
                     /translation="MNLDTLNPAQREAVEKTEGPVLILAGAGSGKTKVLTTRIAYLIE
                     DKGVQAPNILAITFTNKAANEMRERVEQNIGPETKDMWISTFHSCCVRILRKDINKIG
                     YNRSFVIYDSADQVTLVKDCLKELNLSDKVFEPKAVISAISGAKDKLYTPKQFKDINM
                     ADNRMVKIADIYALYQDRLKRNSALDFDDLILKTVELFKANDEVLAYYRSRFRYIMVD
                     EYQDTSKAQYELIKLLAREHQNICVVGDDDQSIYGWRGADIRNILEFEKDYDNVHVVK
                     LEQNYRSTQVILDAANKVISNNIERKRKKLWSEKKEGELIKIQLTGSEIEEADFIADS
                     IAQIARKENRPYKDFAVLYRANAQARPVEDALNRSQIPYNIYGGTKFYERKEIKDLLA
                     YLRVIQNPQDDISIKRIINVPRRGIGLRTIEKIEDRANLKQESIYSVLIDIETNSDIS
                     TKARASISGFVDIIGTLRTIKEVYPVSKLIEKVLDTTGYMDELVEIRNKNEKDLTGKG
                     EEAQDRIDNLREFISIALEFESSNDDTYENKDLETFLTSIALTSESNDEEDNDRVSLM
                     TIHTSKGLEFPVVFLTGMEEGLFPISRAIKSMSDSQIEEERRLCYVGITRAKEELYMS
                     LTEKRTLYGKTNVAIASRFMEELPEECIERLYKVKKELSYSKASYNMLDKYTKKYMST
                     ISKSKVADKVNATIKDSNKETNPDDIKLGSKVHHPKFGVGTVVSIIGTDVTIAFDQQG
                     IKKINKEYTTLNIL"
     gene            complement(5420..6238)
                     /locus_tag="PC466_002869"
     CDS             complement(5420..6238)
                     /locus_tag="PC466_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HDF2770233.1"
                     /translation="MFKINNLTYQYEKNTNALLNINMDFSKGNVIGIIGSNGSGKSTL
                     FMNLMGILKPTSGEILFKEEKLKYDKRSLYNLRKNVGIVFQDPEKQIFYSKVYDDIAF
                     AMRNIGIDEKIIKERINKALVAVNGIDFIDRPVHFLSYGQKKRVAIASVIAMENEIIL
                     LDEPTAGLDPVSTRSIVDIIKGLNKDNIKIVISSHDMNLMYEICDYIYVLDKGILIDE
                     GKAENVFVNENNIIQAGLESPWLVKVHRNMNLPLFKKEEDLYKYWKERELNTNK"
     gene            complement(6231..6929)
                     /gene="cbiQ"
                     /locus_tag="PC466_002870"
     CDS             complement(6231..6929)
                     /gene="cbiQ"
                     /locus_tag="PC466_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ECF transporter T component CbiQ"
                     /protein_id="HDF2770234.1"
                     /translation="MLIIDKYAYTNRLSKVNPNKKVAIGVIFLIASMVIKNIFVLSGI
                     MILMSILVVCVAGIDLKNYLKLLRIPMYFLFLSIGITLVNISFNKADLLYSFEIFSFN
                     VGISKASIDMSIHVLFRAMSCLTCVYFCILTTPFNQLIFFFKKMHLPDTFVELSMLIY
                     RFIFIFLEEFSEIYKSQELRFGYINLKTSYKSLGILGSMLYKRLMTRYDDMCISLDIK
                     LYDGKFHIVGDNDV"
     gene            complement(6932..7216)
                     /locus_tag="PC466_002871"
     CDS             complement(6932..7216)
                     /locus_tag="PC466_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     substrate-binding protein"
                     /protein_id="HDF2770235.1"
                     /translation="MSAKTKTKTNILLLLLVVALIIFPLLVNSGAEYGGADGQAESEI
                     TKINPDYEPWFSSPYEPPSGEIESLLFSAQAALGAGVIGYILGVQKGKRS"
     gene            complement(7206..7958)
                     /locus_tag="PC466_002872"
     CDS             complement(7206..7958)
                     /locus_tag="PC466_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006440549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter permease"
                     /protein_id="HDF2770236.1"
                     /translation="MKQNIKLGVIAALMLIVLTPVTSNAMHIMEGYLPVKWSIAWGVI
                     FIPFFLVGLKSIGKIVKQDPKKKVLLALCGAFVFVLSALKIPSVTGSCSHPTGVGLGA
                     IMFGPSVMFVLGTIVLIFQALLLAHGGITTLGANAFSMAIIGPIISFLIFKALKKKDG
                     NNAMPVFLAAAIGDLATYTVTSIQLALAFPDPSGGVMASAIKFLGIFFMTQIPIAIAE
                     GILTVIVYNLITENGEKSILENNDKGVKANEC"
     regulatory      complement(8147..8339)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            complement(8471..10243)
                     /locus_tag="PC466_002873"
     CDS             complement(8471..10243)
                     /locus_tag="PC466_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitric oxide reductase activation-like protein"
                     /protein_id="HDF2770237.1"
                     /translation="MKWIYDDYEFENRANNLSWTIAGDYNESIDISEKDYSSKEIGLY
                     FAIIAGARRKYVDWDIVKKYLTNRIRKGYNKDIILGLIQVILNTIVEEKVIKDRPGIE
                     DIRRNAYKDIVSRFTKIHNDNIMDKIKYTFVLYNMDKHPALDSMTRRIVNDIRNIDTN
                     QDMMEILKALDVIYLTYFEYILNGEENSLIDENNVESVEVNFDTFADFMYEELYSDEE
                     ENIIESDIDSISSSMLVEGVGDFDDSKCSNSADRVIYVDEDTANKIYSKIEHYYGKTY
                     LSKGEIKKIETQNCRNVHEGCRIHFTDGVLRSECNNVFQLKYVTRQKENNLGKFREHA
                     RMYRQQIKRLKESLSRILIEENAKSRVYSDCGTILANRAWRVGRSNNNKIFYKDIENE
                     KGKYVIDILLDASGSQSRNQGNVAIQAYIIANALTEVGIPNRVMGFSSFLDYTILKRF
                     KDYDDSIKNSENIFEYFCAGNNRDGLAIKSICSGLINRDEENKILIVLSDGRPNDVKI
                     GKSSERTLRGEKAYRGIVGLRDTANEVRKARKQNILVLGVFTGKESELEAERLIYGND
                     FIYSRDITRFSDVVSMYLKKIIRN"
     gene            complement(10257..11186)
                     /locus_tag="PC466_002874"
     CDS             complement(10257..11186)
                     /locus_tag="PC466_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF2770238.1"
                     /translation="MDIIDNLRVQGVDEKLIEDVLYFRNYYGLEKDLEYRVTKSKTYF
                     YGKDILSMCIAAILEEENILLSGPKATGKNLLADNLGEIFNRPQWNTSFHINTDSSTL
                     IGTDTFIDNEVKLRRGSVYECAINGGFGVFDEINMAKNDAIVVVHSALDYRRIIDVPG
                     YERVNLHPATRFIGTMNYEYAGTKELNEALVSRFMVIDIPPIEEDKLMMILKNEFSDA
                     DEEKLIHFAGIFLDLQLKSQNGEISSKAIDLRGLMASLKTIRRGLKPTLAINMGLTGK
                     TFDVYEKEMVGDVIKTRIPNKWESIDVFPISHI"
     gene            11415..11603
                     /locus_tag="PC466_002875"
     CDS             11415..11603
                     /locus_tag="PC466_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2770239.1"
                     /translation="MEYMSCPEVAKKWGISERRVQKLCEESRIPGVSKLGYMWLIPKN
                     AEKPVDGRAKRRKEVQYE"
     gene            11596..12297
                     /locus_tag="PC466_002876"
     CDS             11596..12297
                     /locus_tag="PC466_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2770240.1"
                     /translation="MNSVLIIDDDKELCALMKKCVEQENLSAITAHCGAEGLHLLDKN
                     RHTLSLVILDIMMPDIDGFQVLKKIRETSNIPVIMLTAKNDEDDKVSGLRLGADDYLT
                     KPFSINELMARVNSLIRRYTMLNPAFITDTDCIIINGMIIDKTNRIVSINNIPVQLTS
                     KEFDLLAFLASNKGRVFTKKQIYTQVWEEEYAFDDSNIMSFISKLRKKIEPDPNHPFY
                     ILTVRGVGYRFNKEA"
     gene            12299..13222
                     /locus_tag="PC466_002877"
     CDS             12299..13222
                     /locus_tag="PC466_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2770241.1"
                     /translation="MNTSVYLLLILALSLIIIAYLVSVLLRVRIQLTLIKDALEDIKN
                     GNLNRRILTDENDITKQICYDINEIAINSQFQLIQQKQSEQAYKQLMTSLSHDVKTPL
                     ASLVGYLEAVESKIVVGEEKDEYIHVASNKAHYLKNFVENLFEWVKLDSKEQVFHFDI
                     FDLNELSRNIISDWIPVLESSHFEYEFDIPEIEYFLRIDANAYTRIINNLLQNIITHS
                     SGNKMTLRIFENKEQAQIIITDNGKGISSDNLPHIFERLYQCDHSRASKGNGLGLAIA
                     KELINAHKGNITANSTPGMGTEFTILLPKAL"
     gene            13379..14302
                     /locus_tag="PC466_002878"
     CDS             13379..14302
                     /locus_tag="PC466_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019639192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2770242.1"
                     /translation="MNDFVIETKQLTKIYGNQTVVDKVNLHVKKGRIYGLLGRNGAGK
                     TTIMKMILGLTSITYGEVDVFGENIKGCEKRVYPRIGAIIETPGFYPNLTGTENLEIF
                     AKLRGTAAPNSVKRALEIVGLPYKNKKLFSKYSLGMKQRLGIANAILHDPELLVLDEP
                     TNGLDPIGIAEMRKFIRDLSVEHGKTILISSHILSEISLLADDIGIIDHGVLLEESSM
                     SELEKKNSKYILLQVSDIPKTSLILERQFNTKDYSVQDDHTLRLYNTTLDMGEINKAL
                     VMQNVTVISSQLCNDTLEDYFKKITGGEGIA"
     gene            14295..15032
                     /locus_tag="PC466_002879"
     CDS             14295..15032
                     /locus_tag="PC466_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2770243.1"
                     /translation="MLKLIQTEFLKLRRRKLIWLMLLSALIMPFFALLYFNYFGKTGV
                     EPTKFYKWSAFGYTLWIILPVVLGIFCTMLIHEENQYDMLKQLWIVPISKMGYFFSKF
                     FVVLIYSICFMLITAVASVLFSVLSGYVVFSWASILYLLKKCLEIGVITAFVMLPILA
                     IATSQKGYILPICITLVYAFSGFVIMTINMYLHPLSSMGVIIMRNKDIPGLIFSQEIN
                     VPLAFLCICIWSIVSVLFASIALGRRK"
     gene            15043..15816
                     /locus_tag="PC466_002880"
     CDS             15043..15816
                     /locus_tag="PC466_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2770244.1"
                     /translation="MWKLLWAECQKIRRSKIVWITFFASIMIAVIVFAGGQDVYNDPD
                     LHYGLKSVYDGSRYIDNAGWYMDAVQPWSTFFVLPAVIALLGSYIICREEEEDTIKSL
                     RLIPINETKLTIAKMIITFIFSILLYLLLFTITFLTESVLHFSDLSTKLVLSCMKEYF
                     LDGIGVFFAISPIIALVSRMKKGYWLALVFTEVYSIAGLFAGMSNVLQTFFPIAAIFN
                     ISGYYITTGEKIMGSIISLLLCACLSAFILKGLKHNEKN"
     gene            complement(16357..16965)
                     /locus_tag="PC466_002881"
     CDS             complement(16357..16965)
                     /locus_tag="PC466_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HDF2770245.1"
                     /translation="MSVINSFILQYGLISVFVLIMIEYACFPLPSEVVLPLCGAIAAR
                     NHFGFLTILILSIIAGILGSIFCYTVGNWGGKSIINKIIEICPKAKKGIFASQDYFNK
                     YSSISVCVCRLIPLCRTYISFIAGIAGQNIITFVISSIVGITIWNTSLISIGYIFSES
                     WVRIMSHYNDYKFLVLIIPISIIFIGFVIKSFIHKKHHKIRL"
BASE COUNT         5524 a         2979 c         2150 g         6485 t
ORIGIN      
        1 aaataaatat ataaacaatc ataataaaat ttttttaata aaactttatt ttttagttaa
       61 aatcatacaa tatatagctt tccacaatac aaataaatta aaaagtgaaa tgtatttgtc
      121 taaaaacata ataacatttc actttatcct catttttaag taatatatat ttttaatttt
      181 tatttataac tcaatctagt ttttatataa gttttagttt ttttctacat ctgagtaatc
      241 tattccaaaa gtttctacag taacagactt cataatttgt ggagtttgtg gcttatcagc
      301 tgaatctgtt ctaactgatg ctatttcatc aactgtatcc ataccttcta tcactctacc
      361 aaaacctgca tactgaccat ctaagtgtgg tgagttttta tgcattatga aaaattgaga
      421 accagctgaa ttaggtgcca tagttctagc cattgatatg actcctcttt catgttttaa
      481 attgttagta aatccattac cactaaattc accttttatt gagtgacctg ggccacccat
      541 tcctgtacca tttgggcatc ctccttgtat cataaatcct ggtattactc tatgaaatat
      601 tattccattg taatatcctt catttactaa tgatacaaag tttttaactg tatttggagc
      661 tatatttgga tataactcaa ttttgatttc ttttccattt tccatttcta tagttactat
      721 aggattttta ttttccataa tttattacct tccttttcat tagttaaatt acataattac
      781 atttattata ttatactcta aattaaagtc tatcaagtat attttttcct atttcgtatc
      841 cttcttgata aatagtttta caaaactcat catcaaagtt aagcgtatct ttaggagcaa
      901 attgagtatt aggtctaact actattattt tatcttcatc atatactttt ttaatatcct
      961 ctggcaactc ataattatat tttgtggata ttaaaataat tttatccaca ttatccccaa
     1021 ttaatggttc aattaatgca ctcctaatta aacctccatc taatttgaaa ccatcataaa
     1081 ttccttcttg cacatctttc acaaattgtt ctttaaatcc aagagttgcg tttggatttg
     1141 atggtaacaa cccactgtat gaaatgctga taatggcttc attacgaggc atttttgata
     1201 tgtcaacaat cttttctgat actactttat tatcaacttc aacataatta acataaaagt
     1261 tcatttcttc tatattacta tcatctagtt cccttaggtt gtctatagca ggagaattat
     1321 ccacagtatt atttactatt tttacatttc cattctggat atcttttata tttgtccaca
     1381 ttttctccaa gttatcaaca ttccctgtgt acaaataata tccatttatt gctcctattg
     1441 atgtccctga aatcgaataa aatttattta ttcctccatc atacaaggct ttaactactc
     1501 ctgcttgata agcccctttt gctcctccac cttctaaaca taatcctaat ttcatagtct
     1561 catctccaaa ttgtttatct tatatttata tttcaaaaaa cttactaaat gttttatata
     1621 tactatagtg gtcctcaaca tttcctaatt ctcttataga gtgcattgct aaaattggac
     1681 ttcccacatc cacagatggt atatctatat gagtagaaga tattggacct atagtacttc
     1741 ctcctctttc atctgaccta ttaacaaatt cttgatactc aacattaact tctctacata
     1801 tatttttata aatagctata gaatatccat cactagtata tgcctgacta gcatttatct
     1861 ttataactgg accttttccc attattggtt tattagttgg gtcatgcttt tctggaatgt
     1921 ttggatgaat agcatgagct aaatctgatg atatcataaa agatgaataa atagactcaa
     1981 agaatccctc tctatcctta cccattgata tgcaaattct ctccaatata tttaacaaca
     2041 tgtttgaatc tgcaccttgt ttagtagagc taccaacttc ttcattgtca aatacagcca
     2101 ttacatttac accttgttga cctttagtat taacaagagc attcaaacta gcatgtacca
     2161 ttgcaagatt atcttgtctc ccaatagata taaattcatc attagcccct attaaacttc
     2221 ctttttcaaa ttcatataaa aataaatcaa aatctataat atcttccata tttacatcta
     2281 agttagatgc tatttgcttt ataagaaaat tatctttttc taatgtatca tttaacatcc
     2341 caactaaagg taacatatct ttttgcttat tatatgaatg accatcattt atacttctat
     2401 ttaaatgtat tgctagattt ggtattatac aaattggctt tttaaagtct ataagccttt
     2461 catttggttt taatatacta tcacctttta aaactactct accagctatc ccaagaggtc
     2521 tatccaacca tgtacttaat attgctcctc catagcattc tgtatttaac ttcaaataag
     2581 atttttcagc ttctatttct gcatttggtt taatactaaa tgtaggagaa tctgaatgag
     2641 agcctattat tctaaatcca tctctttcta tatcttctga atttactaca aaagctacta
     2701 tagctgatag attcttagta acataatact ttccaccaac tcttagattc catctttgat
     2761 tcaaaactaa ttcttcaaat ccatttttat ctaagatttc cttagtactc tcgactgcat
     2821 gaaaagacga cggactatca tatatgaagt ctattaagtt tttagcaaag tttatactat
     2881 ccattcctca tttacctcca ttataaaata tttagtgttg tatattcttt atttattttt
     2941 ttaattccct gttggtcaaa agctatagta acatctgtac caattataga aaccactgtc
     3001 ccaaccccaa atttaggatg atgtacctta gaaccaagtt ttatatcatc tggattagtt
     3061 tctttattag aatcttttat tgtagcatta actttatctg caactttaga tttgcttata
     3121 gtactcatat actttttagt atatttatct aacatattat aacttgcttt agaatagctt
     3181 agttcttttt ttactttgta caatctttct atacattctt ctggcagttc ttccataaat
     3241 cttgaagcta ttgcaacatt tgttttacca tataatgttc tcttctctgt caatgacata
     3301 tatagctctt ctttagctct agttatacca acataacaaa gtcttctctc ttcttctatt
     3361 tgtgaatcac tcatagattt tatagctctt gatataggaa ataacccttc ttccatacct
     3421 gttaaaaaca caacagggaa ctctaaacct ttggatgtat gaattgtcat aagcgaaacc
     3481 ctatcattgt cttcttcatc atttgattca gatgtaagtg ctatacttgt taggaatgtc
     3541 tctaagtctt tattttcata agtatcatca ttactacttt caaactccaa agctatagaa
     3601 ataaattctc tcaaattatc aattctgtct tgagcttctt cacctttgcc tgttaaatct
     3661 ttttcatttt tatttcttat ctctacaagc tcgtccatat atcctgtagt atccaagact
     3721 ttttctataa gtttgctaac aggataaact tcttttatag ttctaagagt ccctataata
     3781 tcaacaaatc cacttatact tgcccttgcc ttagtagata tatctgaatt tgtttctata
     3841 tcaattaata ctgagtatat actttcctgt tttaagttag ctctatcttc aattttttct
     3901 atagttctaa gccctatacc tcttctagga acatttataa tcctttttat agatatatca
     3961 tcttgtggat tttgaataac tcttaaatac gccaacaaat cctttatttc ttttctctcg
     4021 tagaattttg taccaccata tatattgtat ggaatttgac ttctatttaa agcgtcctct
     4081 acaggtcttg cctgtgcatt tgctctataa agtactgcaa aatccttata aggtctattt
     4141 tcttttctag ctatttgtgc aattgaatca gcaatgaaat cagcctcttc tatttcgcta
     4201 ccagttaatt gtatctttat aagttctcct tctttttttt cactccaaag cttttttctt
     4261 tttctttcta tattattaga tataacttta ttagctgcat ctaatatcac ttgtgtagac
     4321 ctataatttt gttctaactt tacaacatgt acattgtcat aatctttctc aaattcaagt
     4381 atgtttctta tatctgcgcc tctccatcca taaatacttt ggtcatcatc tccaacaaca
     4441 caaatatttt gatgttctct tgctaataat tttatcaatt catattgagc tttacttgta
     4501 tcttggtact catctaccat tatgtatcta aatctacttc tgtaatatgc taatacttca
     4561 tcattagcct tgaaaagttc tacagtttta agtattaaat catcaaagtc aagtgcacta
     4621 tttcttttta aacggtcttg atataacgca taaatatctg caatcttaac cattctatta
     4681 tctgccatgt tgatatcttt aaactgcttt ggagtataaa gtttgtcttt tgctcctgaa
     4741 attgcactta taactgcttt tggttcaaac actttatcac ttaaatttaa ttcttttaga
     4801 cagtctttaa ccaatgtaac ttggtctgct gaatcataaa ttacaaaact tctattgtaa
     4861 ccaatcttat ttatatcttt tcttagtata cgaacacagc aagaatggaa tgtacttatc
     4921 cacatatcct tagtttcagg acctatattt tgttcaactc tctctctcat ttcatttgca
     4981 gctttgtttg taaatgttat agctaatata tttggtgctt gtacaccttt atcttctata
     5041 agatatgcta ttcttgttgt taatacctta gttttacctg aaccagcacc agccagtata
     5101 agtactggac cttcagtctt ttctactgct tctctttgag caggatttaa tgtatctaaa
     5161 ttcatatttc tcctcctgtt aacagccata aatatatttt aatctaaaat atgaattact
     5221 tcaaattata attatgtatt atattaatag attatttcca atatattaca attaaataac
     5281 atttttccat ataatttatt taattgttta ataaaaaaaa taaccttatg atttggggaa
     5341 tcataaggca cctttaaggg gtctaggtta agggttatta tatataaatc tattttttta
     5401 aaataggttt agggcttaat tatttatttg tattaagttc tctttccttc caatacttat
     5461 acaaatcttc ttctttctta aataagggta aattcatatt tctatgtact tttactaacc
     5521 atggggattc taggccagct tgtataatgt tattttcatt tacaaataca ttttctgcct
     5581 ttccttcatc aattaaaatc cccttatcca atacatatat ataatcgcat atttcataca
     5641 ttaaattcat atcatgactg gatattacta tttttatatt atctttattc aatcccttta
     5701 ttatatctac aatagaccta gtacttactg ggtctaaacc agctgtaggc tcatcaagca
     5761 atataatttc attttccatt gctataactg atgctatcgc tacccttttt ttctgaccat
     5821 aacttaaaaa atgtactggt ctatctataa aatctattcc attaacagct actagagctt
     5881 tgtttattct ctctttaatt attttttcat ctataccaat atttctcatt gcaaaggcta
     5941 tatcatcata tacttttgaa taaaaaattt gtttttctgg gtcttggaac acaataccta
     6001 cattttttct aaggttgtat aaacttctct tatcatattt taacttttct tctttaaaaa
     6061 gaatttctcc agatgtaggc tttaatatac ccattaaatt cataaataat gttgattttc
     6121 ctgaaccatt tgaacctatt atacctataa catttccctt tgaaaaatcc atattaatat
     6181 ttaatagtgc attggtattc ttttcatatt gataagttaa attatttatt ttaaacatca
     6241 ttatccccta ctatgtgaaa tttaccatca tacaatttta tgtctaatga tatacacata
     6301 tcatcatacc ttgtcataag tcttttgtac agcatactgc caagaattcc taatgattta
     6361 tatgaagttt ttaaatttat gtacccaaat cttagttctt gtgacttata tatttctgaa
     6421 aattcttcta aaaatatgaa tataaaccta tatattaaca ttgatagctc aacaaaagta
     6481 tcaggcaaat gcattttttt aaagaagaat attaattgat taaaaggtgt tgtaagtata
     6541 caaaagtata cacaagtcaa acaagacata gctctaaata acacatgaat agacatgtca
     6601 atagatgctt ttgatattcc tacattgaaa ctaaaaattt caaaactata taataagtct
     6661 gccttattaa aagatatatt tacaagagtt attcctatac taagaaataa aaagtacatt
     6721 ggtattctga gtaattttaa ataattcttt aaatctattc cagctacaca aacaactaga
     6781 atactcatta aaatcataat tccacttaaa acaaatatat tttttattac catagaagca
     6841 atcagaaaga ttactcctat ggctactttt ttatttggat ttactttact taatctattt
     6901 gtatatgcat atttatcaat tataagcata attaacttct ctttcctttt tgaacaccta
     6961 atatgtaccc tattacacca gcacctaacg ctgcttgtgc agagaataat aaactttcta
     7021 tttctccact tggtggctca tatgggctac taaaccatgg ttcataatct ggatttatct
     7081 tagtaatttc actctcagct tgaccatctg ctcctccata ttcagctccc gaattaacaa
     7141 gtaatgggaa tatgataaga gctactacta ataaaagtag taatatatta gttttcgtct
     7201 ttgttttagc actcattagc tttaactcct ttatcattat tttctagtat gcttttttct
     7261 ccattttctg taattaaatt atatacaatt acagtaagaa taccctctgc tattgctatt
     7321 ggtatttgag tcataaagaa aattcctaaa aacttaattg ctgaagccat cactccacct
     7381 gatgggtctg ggaaagccag tgctaactgt atcgaagtta ctgtatatgt agccaaatct
     7441 cctattgctg ctgcaagaaa tactggcatt gcattatttc cgtctttttt ctttaatgct
     7501 ttaaatatta agaatgatat aattggtcct ataatagcca ttgaaaaagc attagctcct
     7561 aaagtagtta ttcctccatg tgccaatagt aatgcttgga atattagaac tatagttcca
     7621 agaacaaaca ttacacttgg tccaaacatt attgctccaa gacctactcc agtaggatgt
     7681 gaacaacttc ctgttactga aggtatcttt agtgctgaca atacaaatac aaatgctcca
     7741 cacagcgcta ataatacttt ctttttaggg tcttgcttta ctatttttcc tattgatttt
     7801 agtcctacta aaaaaaatgg tataaatata actccccatg ctatagacca ttttactggt
     7861 aagtatcctt ccattatgtg cattgcattc gatgtaactg gagttaaaac gattaacata
     7921 agtgcagcta taacccctaa tttgatattt tgtttcattt tactatcccc tctctccctt
     7981 tctaataatt aaaatataaa taatatatgt ctgatttatt ttaaaaataa aaataaaaaa
     8041 gcctaactcg atggctaggc ttctaatttt cgataatcca aatacaaaca cataaaatga
     8101 acatatctgt ataattatta taagaaactt tctccatccc cgaagaaatt actttaatat
     8161 tttaggcagg tctcctgact tagcttcttc ctactcctct tccttcccat gagatataaa
     8221 aaatatcatc atagtggcta acaaaagttt cgtctgcatc acagtagcgg gggctgtaaa
     8281 ggaatttaac ctttttccct attaatcttg cttaaagaac ctataatatt atatatttaa
     8341 tttttaaatt attcttaaat cattttctat ataaatcatt gtataccttt tctgtgaaaa
     8401 tttctacatt ttttataaat tttattcatt tttatatttt tatgtatata aattcttttt
     8461 tgtaagttta ttaatttcta attatcttct ttaaatacat tgaaactaca tcagaaaatc
     8521 tagttatatc tcttgaatat ataaaatcat ttccatatat taatctttca gcttcaagtt
     8581 ctgattcttt tcctgtaaat actcctagta ctaatatatt ttgctttcta gcttttctca
     8641 cttcattggc tgtatctctc aaaccaacta tacccctata agccttttct cctcttaatg
     8701 ttctctcact actttttcct atctttacat catttggtct tccatcgctg agaactatca
     8761 ggattttatt ttcttcatct ctatttatta gaccactaca tatagatttt attgccaaac
     8821 catctctatt attaccagca caaaaatatt caaatatatt ttcactattt tttatactat
     8881 catcataatc tttaaatctt tttaatattg tatagtctaa aaaactagaa aatcccatca
     8941 ctctatttgg tatgccaact tctgttagag catttgcaat tatgtaagct tgaattgcca
     9001 catttccctg atttctactt tgagagccac ttgcatccaa taatatatca ataacgtatt
     9061 tccctttttc attttctata tctttataaa atattttatt attattactt ctaccaactc
     9121 tccaagctct atttgctaat atagtaccac aatcagaata tactctactt ttagcatttt
     9181 cttctattaa aattcttgac agactttctt ttaatctctt tatttgctgt ctatacattc
     9241 tagcatgttc tctaaatttt cctaaattat tttctttttg tcttgttaca tattttagtt
     9301 gaaatacatt attacactca cttctaagaa ctccatctgt aaagtgtatt ctacaacctt
     9361 catgaacatt tctacaattt tgtgtctcaa tttttttaat ttcaccttta ctcaaataag
     9421 tttttccata ataatgttct atttttgaat atatcttatt tgcagtgtct tcatcaacat
     9481 atataactcg gtctgctgaa ttgctacatt tagaatcatc aaaatcccct acaccttcta
     9541 caagcatgga tgaagatatt gaatctatat cactttcaat aatattttct tcttcatcac
     9601 tataaagttc ttcatacatg aaatcagcaa atgtatcaaa atttacttct acactttcta
     9661 cattattttc atcaataaga ctattttctt ctccatttaa tatgtattcg aaataagtta
     9721 aatatataac atctaatgct tttaaaatct ccatcatatc ttgattggta tctatatttc
     9781 ttatatcatt aactattctt ctagtcatac tatctaatgc tgggtgcttg tccatattat
     9841 aaagtacaaa tgtgtattta attttatcca taatattatc attgtgtatt ttggtaaaac
     9901 gtgaaacaat atctttataa gcatttcttc ttatgtcttc tatccctggc ctatctttaa
     9961 tgaccttttc ttcaactatt gtatttaata taacttgaat tagacccagt ataatatctt
    10021 tgttgtatcc ttttcttatt ctatttgtaa gatatttttt aactatatcc caatctacat
    10081 actttcttct agcacctgca attattgcaa aatatagacc tatttctttt gaagagtaat
    10141 ctttttctga tatatctata ctttcattgt aatcaccagc tattgtccat gataagttat
    10201 tagctctatt ttcaaattca taatcatcat atatccattt cataatctca cctatattaa
    10261 atatgactta ttggaaatac atctatactc tcccatttat taggtattct agttttaatt
    10321 acatctccaa ccatttcttt ctcatataca tcaaaagtct ttcctgtaag tcccatatta
    10381 attgcaagag ttggttttaa tcctcttctt atagtcttaa gagatgccat aagaccacgt
    10441 aaatcaatag ctttactaga tatctctcca ttttgagact tcaattgtaa atctaaaaat
    10501 attcctgcaa agtgtattaa tttttcttca tcagcatctg aaaattcatt ttttaaaatc
    10561 atcattaact tatcttcttc tataggagga atatctatta ccataaatct agataccagt
    10621 gcttcattaa gttcttttgt tcctgcatat tcataattca tagtcccaat aaatcttgtt
    10681 gctggatgta gattgactct ctcataccca ggtacatcaa ttattcttct atagtctaaa
    10741 gctgaatgta ccacaactat agcatcattt tttgccatat taatttcatc aaatactcca
    10801 aaacctccat taatagcaca ctcataaact gagcctcttc taagtttaac ttcattgtct
    10861 ataaatgtat ctgtacctat aagtgttgaa ctgtctgtat ttatatgaaa tgatgtattc
    10921 cactgaggtc tattaaatat ttcccctaga ttatcagcaa gtaaattttt tcccgttgcc
    10981 tttggtcccg ataataatat attttcttct tctaaaatag ctgctataca catagacaag
    11041 atatctttac cataaaaata agttttagac tttgttactc tgtattctaa atctttttct
    11101 aaaccataat aatttctaaa atacagtaca tcttcaataa gtttttcatc taccccttgc
    11161 acccttagat tatctattat atccatattt ttaccccttt tatataaata gtatttgttt
    11221 catttcttat caccatttta gcataaaagg atataagcta aaattgattt tttaatctcc
    11281 cccattttaa gtaaaaccat gcaccatttt atcactacaa aattaagagt actacttact
    11341 gatatttctt gattttgttc gtctatacgt atataatata tgctgataaa ttatgaggaa
    11401 aggatgattg aaatatggaa tatatgtctt gcccagaagt agcaaaaaaa tggggcattt
    11461 ctgaaagaag agtacaaaaa ctatgtgaag aaagtcgcat accaggagtt tcaaaactcg
    11521 ggtatatgtg gctgatacca aagaacgcag aaaagcctgt tgatggtaga gcgaaaagaa
    11581 gaaaggaagt acaatatgaa tagcgttttg attatagatg atgacaaaga actttgtgct
    11641 cttatgaaaa aatgtgttga gcaagaaaat ttatctgcta ttactgcaca ttgtggtgca
    11701 gaaggtctac atttgctcga taaaaataga cacacactct ctcttgtaat tttagacata
    11761 atgatgccag atatagacgg ttttcaagtt ctgaaaaaaa ttagagaaac aagtaatatt
    11821 ccagtaatta tgcttactgc taaaaatgac gaggatgata aagtttccgg actacgttta
    11881 ggtgctgacg attacctaac aaaaccgttc agcataaacg aacttatggc tcgtgtcaat
    11941 tctcttattc gtcggtatac tatgttaaac cctgctttta taacagacac agattgcata
    12001 ataataaatg gcatgattat tgacaagaca aaccgaattg tttctatcaa taatattcct
    12061 gttcaactta caagcaaaga atttgattta cttgcttttc tggcttctaa taagggacgg
    12121 gtatttacca aaaaacagat ttatacacaa gtatgggaag aagaatatgc ttttgacgat
    12181 agtaacatca tgtctttcat cagtaaattg agaaaaaaga ttgaaccaga ccccaaccat
    12241 ccattttata ttttgacagt tcgtggtgtc ggttatcgtt ttaataagga ggcttaacat
    12301 gaatacaagt gtctatctac ttttgatatt ggctcttagc ctgattatta tagcgtacct
    12361 tgtttctgtc ctgctacgtg tccgaataca acttacactt ataaaagatg ctttagagga
    12421 tataaaaaat ggaaacctta atcgccgtat tttaacagat gaaaacgaca ttacaaaaca
    12481 aatttgctat gatattaacg aaatagcaat caatagccaa tttcaactta ttcagcaaaa
    12541 acaatcagaa caagcctaca aacagctaat gacaagtctc tcccatgatg taaaaactcc
    12601 acttgcttct ttggtcggtt atttggaagc agtagaaagt aaaattgttg taggagagga
    12661 aaaagacgag tatatccatg ttgcgtctaa taaggctcat tacttaaaga attttgtaga
    12721 aaatctattt gaatgggtaa aattggattc taaggaacaa gtttttcatt ttgatatttt
    12781 tgacttgaat gaattatccc gtaatattat atctgattgg atacctgttt tagaaagcag
    12841 tcattttgaa tatgaatttg atataccaga aatagagtac ttcttacgta tagacgcaaa
    12901 tgcatatacc cgtatcatta ataacctatt acaaaatatt attacccata gtagtggcaa
    12961 caaaatgaca ttgagaattt ttgaaaacaa agagcaagct caaattataa taacagataa
    13021 tgggaaaggt atatcttcag acaatctccc acatattttt gaaaggttgt accaatgcga
    13081 ccattcacga gcttcaaagg gaaatggttt aggcttggcg attgcaaagg aacttattaa
    13141 cgctcataag ggaaatatta ccgccaacag cactcccggt atgggaacag aatttacaat
    13201 attgcttcct aaagccctgt aaaagtacga ggctttctta ctctaaaaca agataaaagc
    13261 aagattatgg caaggttttg gcaaggttca tgttttataa ttctaattgt agttgatttt
    13321 gacgttgtat caactatctt ttgtagaaac aaatttatta aaagtgagga aattatatat
    13381 gaatgatttt gtgattgaaa caaagcaact tacaaaaatt tatgggaatc aaacagtagt
    13441 tgacaaagtc aatctccatg taaaaaaagg ccgaatatat ggtctgttag gacgcaacgg
    13501 agctgggaaa accacaatta tgaaaatgat tttaggattg acttcaatca cgtatggcga
    13561 ggtagatgta tttggagaga atattaaggg atgtgaaaaa cgagtatatc cccgtatcgg
    13621 tgcaattatc gaaacgccag gattttatcc taatctgaca ggaacggaga acttggagat
    13681 ttttgcaaaa cttcgtggta cagccgcccc taattctgta aaaagagcat tggagattgt
    13741 aggcttacct tataaaaata aaaagctgtt tagtaaatat tcacttggca tgaaacagcg
    13801 acttggtatt gccaacgcta tcctgcatga cccggaactg ttagttttag atgagccaac
    13861 caatggactt gaccctattg gtattgcgga gatgagaaag tttattaggg acttgagcgt
    13921 tgagcatgga aagacaattc ttatctccag tcatattctt tcagaaatct cattgttggc
    13981 tgatgatatt ggaattatcg accacggtgt tcttttggaa gaaagtagta tgagtgaact
    14041 agaaaagaaa aacagtaaat atatcctgct acaagtttca gatattccaa agacatcact
    14101 tattttagag cgtcaattta acacgaagga ttattccgtt caagatgacc acactttacg
    14161 cctttataac actactctgg atatgggtga aatcaataaa gcacttgtaa tgcagaatgt
    14221 aactgttatt agttctcaac tttgtaatga tactttagag gactacttta aaaaaatcac
    14281 aggaggagag ggcattgctt aaacttattc aaacagaatt tcttaaactg cgtcgtagga
    14341 aacttatttg gctgatgttg ttgtctgctc tcattatgcc gtttttcgca ctactatact
    14401 tcaattattt tggtaaaaca ggtgttgagc caacaaagtt ttataaatgg tctgcatttg
    14461 gttatacact ttggattatt ttgcccgttg ttttgggtat attttgcacc atgcttatac
    14521 acgaagaaaa ccagtatgat atgctcaaac agctttggat tgtacctatt agtaaaatgg
    14581 gatacttttt tagtaaattt ttcgttgttt tgatttactc tatttgtttt atgctgatta
    14641 cagccgttgc ttctgtgtta tttagtgtac tttctggata tgtcgtattt agctgggcaa
    14701 gcattttata tttgttgaaa aaatgtttag aaattggtgt aatcactgct tttgtaatgt
    14761 tgccgatttt ggcaatcgct acatctcaaa aaggatacat tctcccaatt tgtatcacat
    14821 tggtatatgc cttttccggt tttgttataa tgacaataaa tatgtattta cacccattat
    14881 ccagtatggg agttattatc atgagaaata aagacattcc aggtcttata ttttcacagg
    14941 aaattaatgt cccattagca tttctttgta tttgtatttg gagtattgta tcagtattgt
    15001 ttgcaagcat tgcactagga agaagaaagt gaggtgtaga taatgtggaa attactttgg
    15061 gctgaatgtc aaaaaattcg tcgttcaaaa attgtttgga ttacattttt tgcatccatt
    15121 atgatagcag tcatagtttt tgcaggaggg caggatgtat ataatgaccc agatttacat
    15181 tatggcttaa agagcgttta tgacggttca cggtatatag acaatgcagg ttggtatatg
    15241 gacgcggtac aaccttggtc aacttttttt gttcttcctg ctgtcattgc cctattagga
    15301 agctatatta tttgtcgtga agaagaggag gacactatta aatccctgcg tcttattccc
    15361 ataaatgaaa caaaattaac catagcaaaa atgattatta cttttatatt cagtatactt
    15421 ctttatttgt tactctttac tataacattt ttgactgaat ccgttttaca tttttccgat
    15481 ttatcgacaa aactggtttt aagttgcatg aaagagtatt ttcttgatgg cataggtgta
    15541 ttctttgcaa tttctcccat tattgccttg gtatcgcgca tgaaaaaagg atattggctt
    15601 gcattagtat tcacagaagt ttattctatt gctggactat ttgcgggtat gtcaaatgtc
    15661 ttacaaacct tttttcctat tgcagcaata tttaatattt ctggatacta tataactact
    15721 ggagaaaaaa ttatggggag tatcataagt ttattacttt gtgcctgcct ttctgcattt
    15781 atactgaaag ggctaaaaca caatgaaaaa aattgaaata ggtatatcaa aatgaaaaag
    15841 ataaaaaaac tgattattct aattgtattc ttgtttcttt ttggcatgtt acactgttat
    15901 actgaatgga aattcaacaa tgacccacct aaaggggtaa tagaaagaat aaatgagtgg
    15961 actgataaga ttggactgga ttagtaactt atgttaatta tagtgaatgt aatattagca
    16021 agttattgtt tcgtatttta atactataac tttaaatatt tggttttaat cttccgaacg
    16081 aatataaaaa aactgtcaca gaggcaacat atttttgaat atttataaag tggtagtttt
    16141 gattttcaaa gctgccgcct tttcttctat ataagcaaac ttatcctcaa caaagtgtaa
    16201 aacatggtac attttaagaa aaaagtacca cagacacaag caataaaaga aacgccgaga
    16261 acctacaaaa acgtagtgct tatgcagatt tacgacgcct tctattttct caaccgtctt
    16321 aatgaccttg tacaaaagaa atttttctaa tattttttat aatcttatct tgtgatgttt
    16381 tttatgtata aatgacttaa taacaaatcc aataaaaatt atggatattg gtataattag
    16441 aacgaggaat ttataatcat tataatgtga cattattctt acccaactct cagaaaaaat
    16501 atatcctata ctgattaatg aagtattcca tatggttatt cccacgatag atgatattac
    16561 aaaagttata atattttgac ctgctatacc tgctataaaa gatatgtatg ttctacataa
    16621 agggattaat ctacatacac aaacagaaat agaagagtat ttattaaaat aatcttgaga
    16681 tgcaaatatt cctttctttg cctttggaca tatctctatt attttattta tgatagattt
    16741 acctccccaa tttcccactg tataacaaaa tatcgaacca agtatacctg caattatact
    16801 taaaattaaa attgtcagaa atccaaaatg atttcttgca gcaattgctc cacataaagg
    16861 taaaacaact tcgctaggta atggaaaaca agcatactca atcataatta atacaaatac
    16921 agagattaat ccatattgta aaataaaact attgattaca gacacttact tatctatctc
    16981 ctttcttatt taaaggtttt aagggtacat attctaagga ttctcaccct atatttaaag
    17041 aatcaatctc tttaaactat tatatgtatt tacacaaagc atttataaca tactttaaaa
    17101 atagtacctt aaaataagaa acttaataaa taaaaaaa
//
LOCUS       DAMJYN010000079        17067 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.082, whole genome shotgun sequence.
ACCESSION   DAMJYN010000079 DAMJYN010000000
VERSION     DAMJYN010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17067)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17067)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17067
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.082"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(100..786)
                     /locus_tag="PC466_002882"
     CDS             complement(100..786)
                     /locus_tag="PC466_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HDF2770246.1"
                     /translation="MFGVIANSLAIAGGCIVGLIIKGGLPQRVSDTIMNGIALCVLYI
                     GISGALEGKNTLVTIISVAVGALIGELIDIDKWVNKLGAFLQSKFSKGNKKDSIAEGF
                     ISSSLLFCIGAMAVVGSLESGLTGSHDTLFVKSVIDGIASIIFTASLGIGVMFSAISV
                     FLYEGIICVGASFLNGFLSDPVVTEMTAAGSLLIIGLGLNVLKLTNIKVANLLPAIFI
                     PILFGVFGII"
     gene            complement(835..1368)
                     /locus_tag="PC466_002883"
     CDS             complement(835..1368)
                     /locus_tag="PC466_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HDF2770247.1"
                     /translation="MSDLNNKKEQDENESSMNETKIYDILDKLNVEYDVVEHEAVYTA
                     EQLVILDGITKGCQCKNLFLRNAKGNKYYLIVVKGEKQVDLNSLKDKIGSSRLSFASP
                     ERLYNVLKLLPGSVNPFSLINDTERKVELYIDKDVIKEDYLNFHPNINTKTVNISRKG
                     FEEFLEYLKYPIQSIDA"
     gene            complement(1412..2044)
                     /locus_tag="PC466_002884"
     CDS             complement(1412..2044)
                     /locus_tag="PC466_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclase family protein"
                     /protein_id="HDF2770248.1"
                     /translation="MKVFDLTHVTHNDMPVYAEPNRPDIKKVAIIEENGYQETLISVF
                     SHNGTHMDSPRHMYTKGETLDKLDIENFVGKAYVLELEKGNENIELEYLKKYEDEIKN
                     SDFIIFKSGWSKFWDKKQYYVGYPTLTKEAANYIANTNIKGIGIDMLSVDRYNTSVFE
                     VHHILFEKGKIIIENLTNLENVPEKFLFIAAPFKYNDADGAPVRAIAIVE"
     gene            complement(2134..3213)
                     /locus_tag="PC466_002885"
     CDS             complement(2134..3213)
                     /locus_tag="PC466_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HDF2770249.1"
                     /translation="MKIAIFLGAGASAAENLPIQNELFSEYFKKLNPTNYNTKMNREL
                     YIFFKQMFNIDIVKDNIDNANFPTFEEVLGLLDLAEQRKEAFRNFGLENLNNRSDSIR
                     FLRQYLILLMAEAIHNTPRTDNKYHKLLVENLLENDLLLDTTFISANYDIHIDNTVTG
                     LRDKNDLPIMLDYGVEFTNFKEELNWRKPKEPLIKLYKIHGSLNWLYCPICNSVTLTP
                     HEGGVMKLIENSSETKCLECGELTEPIIVPPTYFKNMSNIFLSNVWNETEKTLRDTDL
                     LIFCGYSFPEADMHIKYMLKRVQTNRKKPPLKIMVFNNHSQKQRITLKKEEGRYKRFL
                     GEDVIFTDNSFQDFSVNPLRFIKNI"
     gene            complement(3346..4692)
                     /gene="pepV"
                     /locus_tag="PC466_002886"
     CDS             complement(3346..4692)
                     /gene="pepV"
                     /locus_tag="PC466_002886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HDF2770250.1"
                     /translation="MKEQIKEKVNSLQDEMISSIQESVKIPSVISEATENCPFGENVD
                     KALRGILDLCKSLGFKTVYKDGYYGYAEIGQGEKMIGILGHVDVVPEGDLESWNYPPF
                     EAVLEDGKLYGRGTQDDKGPTISAIYAVKALMDLNVDFNKRIRFIFGADEENLWRCIN
                     KYKENNEEIPNYGFTPDSRFPITNAEKGLLQVHLTCDSKSDIELSVGKALNAVPGKAI
                     YIGKYSDKLKKELDKLNFEYTVEGNKICIIGKSVHSAASDTGINAVARLCIALNNIGI
                     DSNIIKFLAEVIGEDANGNNIIPNCKDDVSGKLTVNIGRVTIDNEKEFAGIDVRIPVT
                     YKKDDFVKELKKMTDKYNLNYEEYDFLDSIYVPEDTLLVKTLRKVYEEETGLDGTPLS
                     SGGATYARALDNCVAFGAIFPGKPETEHQANEYLIVEDIIKATQIYALSIYELLKI"
     gene            complement(4761..6041)
                     /locus_tag="PC466_002887"
     CDS             complement(4761..6041)
                     /locus_tag="PC466_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine gamma-lyase family protein"
                     /protein_id="HDF2770251.1"
                     /translation="MLNETKELLKDYYGIDDDTFKLSQEIMEEIKDKFEEIKEIREYN
                     QYKVLKAMQESKLSDMHFNWTTGYGYNDIGREKIEEIYSKVFNTEDALVRPIIVNGTH
                     ALTLCIQGIVRPGDEILSVTGRPYDTLEGVIGIREEKGSLKEYGVTYDDVDFLEDGNL
                     DLEGIKNKINDRTKLVMIQRSKGYSWRKSLSISDIKEAIEVIKSVKPEAIVMVDNCYG
                     EFLDTKEPTDVGADVMAGSLIKNPGGGLALTGGYIAGRKDLIELISYRMTSPGIGKEC
                     GLTFGTTRNVLQGFFLAPYIVSQAVMGAIFCSRAFEKLGYDVLPKYDDLRSDIIQCIR
                     LNNADEVISFCEGIQEAAPVDSYVKPVPWDMPGYESEVIMAAGAFIQGSSIELSADAP
                     IRPPYNVYFQGGLTFDHSKMGTLKAIEFIKKLKK"
     gene            complement(6168..6428)
                     /gene="hfq"
                     /locus_tag="PC466_002888"
     CDS             complement(6168..6428)
                     /gene="hfq"
                     /locus_tag="PC466_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA chaperone Hfq"
                     /protein_id="HDF2770252.1"
                     /translation="MKNTVLNLQDLFLNNARKERIPVTIYLVNGVQVKGLVKGFDSYI
                     ILIEGDNRQQNMIYKHAVSTIQPGKYINLTNQNQNNNNNNNR"
     gene            complement(6542..7477)
                     /gene="miaA"
                     /locus_tag="PC466_002889"
     CDS             complement(6542..7477)
                     /gene="miaA"
                     /locus_tag="PC466_002889"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HDF2770253.1"
                     /translation="MKKIPLIILTGPTAVGKTDLSIKLAKDIDAEIISADSMQIYEYM
                     DIGSAKVTEEEMQGVKHYLIDEVKPDYPFSVSEFQQRAKKYIHEINEKGKCVLVTGGT
                     GLYLNSLIYNMDFAQSDANNELREELQKQLAEKGIDYMHNKLKELDEESANRIHKNNT
                     KRVIRALEVCLSGKKMNDFSSDLKFNEEYQPIIIVLNRDREHLYQRINMRVDIMIKNG
                     LVEEVKKLLSMGFKKDMISMQGIGYKEILKYLDGEYTYEEAIEIIKRDSRRYAKRQIT
                     WFKRYKTARWFDLDQYENIDELKNEIILYIKDSIK"
     gene            complement(7515..9482)
                     /gene="mutL"
                     /locus_tag="PC466_002890"
     CDS             complement(7515..9482)
                     /gene="mutL"
                     /locus_tag="PC466_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HDF2770254.1"
                     /translation="MKNIINILDDLTINKIAAGEVVERPSSVVKELIENSIDAGANKI
                     SIDIIDGGKSLIKITDNGIGIPSSEVEKSFLRHATSKIKKIDDLYDLYSLGFRGEALA
                     SISAVSKLEMTTKTKDEIIGTKIYVEGGKIISKEPIGSTNGTTIIIKDIFFNTPARQK
                     FLKSTHAETINISDLINKLAIGNPNIQFKYTNNNKQMLNTPGDGKLVNTIRSIYGKEI
                     TENIIDVEFKCNHFKMNGYIGNNNIYRSNKNLQHIYINKRFVKSKIIIDAITESYKSI
                     IPIGKHAVCFLNIEVDPSCIDVNIHPNKLEIKFEKEQEVYIELRDFLKVKLIHSNLIG
                     KYATYSDKKTQPRIAINSREKSTDYKLRNNDLLESTPKNSNITKDKDEVIEVVTLSSE
                     KPINEFQSVSEVLNASVEDDVKNINYLSEDSANDNIQEEFQVDGIKNEGNYYLGDSIK
                     DSEEEYLCSSKRKFSLYGYSVIGVVFNTYIILSKDDSMYLLDQHAAHERILYERYMEK
                     FYRQDINMQILLDPVVIEVSNVDMLQIENNLELFMKFGFELEIFGNNHIMVRCVPTIF
                     GVPETEKFILQIIDNIEEITSNYDLKGERFASMACRSAIKANDKIYDIEIKSLLEQLE
                     KCENPFTCPHGRPIMVEISKTEIEKMFKRIM"
     gene            complement(9493..12336)
                     /gene="mutS"
                     /locus_tag="PC466_002891"
     CDS             complement(9493..12336)
                     /gene="mutS"
                     /locus_tag="PC466_002891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HDF2770255.1"
                     /translation="MQIDMNKLTPMMKQYLEVKNRYKDCILFFRLGDFYEMFFEDALV
                     ASKALEIALTGKACGLEERAPMCGVPFHSANSYISKLVENGYKVAIGEQMEDPSTAKG
                     IVRREVIRVITPGTVLDGNLLENKKNNYLLSLYKDGTNIGLTYVDISTGETNATCLNE
                     DKVIEEIAKIHPTEIIINDLDFIEKLRDIATVSNIYINESFSDNYLDINILKEYFPDV
                     YLQKLKFDDKGLIKSSLSILLNYIYNTQKQITSNINNINIYNSSEYMVLDMFTRTNLE
                     LTQTIRGNKKKGSLLHVLDKTSTAMGGRLLRKYVEEPLINKSKIENRLDVIEEIKDDF
                     ILREDLNDILKNIYDIERICGKIAFERVTPKELIHLKNSIEKLPNLKDTINLSNAKIL
                     KEYVSEMDKLDDIYNLIDEAILEEPTITIKDGNIIKSDFSDELKELREISKNGAFLVK
                     EIENREREKTGVKSLKIGFNKVFGYYIEITKANFKQAKLDETYIRKQTLSNAERYITP
                     ELKEIEEKILHAEEKIKSLEYEIFVEIRDTIYKNIDRIQKVAKTIANIDVFVSLATVA
                     HINNYVKPAINENNKLDIRNGRHPVVENIVGEENFVPNDTYLNRGENIINIITGPNMS
                     GKSTYMRQTAIIALMAHIGSFVPAESADIPILDRIFTRVGASDDLSQGQSTFMVEMNE
                     VSLILKNATERSLVILDEIGRGTSTYDGISLAWSIVEYIQKNIRCKTLFATHYHELTD
                     LEEEFKEVKNYSIAVKEDGEGIIFLRKIIPQGADKSYGIYVAKLAKLPDEVIERAKYI
                     LKDLEKNHVYNSVAINGDKENNNIINSNLDEELVKVNQSNFKNKYESLKIEHELIVKD
                     YKHIKKDYDKLNSKFKALNDEVALMKQNDDKEKINQEDSVKEVALTQISFDSVNRDIL
                     SEEILNLDILNMTPLDAINSLYNLQRKAKEIKS"
     gene            complement(12499..13233)
                     /locus_tag="PC466_002892"
     CDS             complement(12499..13233)
                     /locus_tag="PC466_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2770256.1"
                     /translation="MLTQMNFYHNKKVKVSIENVSKTYKDIEVLKDISIDVYEGEFVS
                     ILGPSGCGKSTIFNIITKLTDYDSGKVNINGKYSYMYQKDLLLPYKTIIDNVSLPLIL
                     KKEKKSKARSMVKPYFEVFGLSGYEDKYPSELSGGMRQRANFLRTFINSNDIMLLDEP
                     FGALDSLTKTSMQKWLLDVKKKVNSTILLITHDIDEAIMLSNRIYVISKKPSIVKKEF
                     VIDSRKLNEDNLENIIKLKKEIISLL"
     gene            complement(13202..14215)
                     /locus_tag="PC466_002893"
     CDS             complement(13202..14215)
                     /locus_tag="PC466_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF2770257.1"
                     /translation="MNFKKLGILGLVSVFTLATITGCSSNNNKDKNNDKDTSSKKVTM
                     VLDWTPNTNHTGLFVALDKGYYKEEGLDVEIVQPPESGAETLVATGKADFGISYQEQV
                     TYAKTSEDPLPIKAVATVIQHNTSGFASPKEKNITTAKDFEGKTYGGWGSPSEEAVFK
                     AVMKKNGADFNKLKIVNTGQDDFFAAMKTVDFAWIFEGWDAVKADLIGYDLNFIPVKD
                     LDERLDYYTPLIISNETVLKDNPELAKKFLKATTKGYEYAIKNPEESAKILVKHAPEV
                     DEKLALKSQEYLASKYKDDAPRWGEMKDSVWNNYTSFLKEYKLIDKDMKASDAYTNEF
                     LPQ"
     gene            complement(14237..15007)
                     /locus_tag="PC466_002894"
     CDS             complement(14237..15007)
                     /locus_tag="PC466_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2770258.1"
                     /translation="MKNLEIIDKVKDSIYPIATFLFILILWQSMVGVLEVPQYILPTP
                     VDIINVFFKDYQNLSMHAVVTIGEAILGFIVAIIISLVIGILMDFVSIIKKCLYPIML
                     VTQMIPTIIIAPLFMIWFGFGTMPKVLMVMLTCFFPILISFVDGIENIDKDYLNLFKT
                     MDSNKVNTFIHLKFPMAMDKFFSGLKISATYAVMAATVAEWLGGTKGLGVYMLRSKSA
                     YALDKVFASTILVVIFSLMFVGIVQAVKKVVIRHRLID"
     gene            complement(14982..15272)
                     /locus_tag="PC466_002895"
     CDS             complement(14982..15272)
                     /locus_tag="PC466_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MTH1187 family thiamine-binding protein"
                     /protein_id="HDF2770259.1"
                     /translation="MVIADIAVMPLRPYKGEEEMYKVVDACIAEIEKSGLKCEIGAMS
                     TTVEGDFDEVFELLKKVHKIPFNLGCERVITVARVDEKAGGLTIDEKLRNHR"
     regulatory      complement(15403..15502)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     regulatory      16122..16211
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            16264..16440
                     /locus_tag="PC466_002896"
     CDS             16264..16440
                     /locus_tag="PC466_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770260.1"
                     /translation="MFMDKMDRCTHILTAYICSSRDYCNFIDTQLNDFILEYGENVVE
                     SCLHQVMVLVSRYN"
     gene            complement(16555..16911)
                     /locus_tag="PC466_002897"
     CDS             complement(16555..16911)
                     /locus_tag="PC466_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2770261.1"
                     /translation="MDIDNNFEEFPNIEERQKDFNCSIGFTMTVIGSKWRAIILWHIL
                     KQEPIRYSQLKKDVVHISHKILSQELKYLERDGLIKRISYPTIPPKVEYLSTKRGKSL
                     ESILLELCNWGKQYMR"
BASE COUNT         5386 a         2928 c         1800 g         6953 t
ORIGIN      
        1 aatttgatga taaaagctat tttccttcta aataaaaaat ttgtctaaag tttctaaaaa
       61 atttagacaa atcttaggtt attattcttt aaattatttt taaattattc caaatacacc
      121 aaataatatt ggtataaata tagctggtaa caaattagct acttttatat tcgttaattt
      181 aagtacattt agaccaagtc ctataattaa taaacttcca gctgctgtca tttctgtgac
      241 tacaggatca cttaaaaatc catttaaaaa tgatgctccc acacatataa taccttcata
      301 caaaaataca gatattgcag aaaacattac acctatacct aaagaagcag taaatataat
      361 tgaagctatt ccatctataa cagattttac aaataaagta tcatgacttc ctgtaagacc
      421 actttctaat gaaccaacta ctgccatggc tcctatacag aataataaac tagatgatat
      481 aaaaccctct gctatagaat cttttttatt tcctttagaa aatttacttt gtaaaaaagc
      541 acccaactta tttacccatt tgtcaatatc tattaattct cctatcagag cacctacagc
      601 tacggatatt attgtcacta atgtgttttt tccttctagt gctcctgata taccaatgta
      661 caatacacat aaggcaattc cattcattat agtatcactt actctttgag gtaatcctcc
      721 ttttattata agacctacta tacatccacc tgcaattgct agactatttg ctattactcc
      781 aaacattttt tctcccctcg attagctaat tgaaatttat cctattatta aaacctaagc
      841 atctatactt tgtattggat attttaaata ttccaaaaat tcttcaaaac cttttctaga
      901 tatatttaca gttttagtat ttatgttagg atgaaaattt aagtaatctt ctttaattac
      961 atctttatct atgtaaagct caacttttct ttctgtatca tttattaatg aaaaaggatt
     1021 tacacttcca ggaagaagtt taagtacatt gtatagtctt tcaggtgaag caaacgataa
     1081 tctagaactt cctatcttat ctttaagtga gtttaaatca acttgttttt ctcctttaac
     1141 tacaataaga taatacttat ttcctttggc atttcttaaa aataaatttt tacattgaca
     1201 cccctttgtt attccatcta aaatgactaa ttgctctgct gtatatacag cttcatgctc
     1261 tactacatca tattcaacat ttaatttatc caaaatatca tatattttag tttcattcat
     1321 gctagattca ttttcatctt gttctttttt attatttaaa tcactcatac ttttctcctt
     1381 aaacacttca tcataatatc attgtgaggt attattctac tatagctatt gctcttactg
     1441 gagctccatc agcatcatta tacttaaatg gtgctgctat aaatagaaat ttttctggaa
     1501 cattttctaa atttgtaaga ttttctatga ttatttttcc tttttcaaat aaaatatgat
     1561 gcacttcaaa tactgatgtg ttatatctat ccactgatag catatctatt cctatgcctt
     1621 ttatattagt attagctata tagtttgcag cttcttttgt taatgtagga taacctacat
     1681 agtactgctt tttatcccaa aattttgacc aacctgattt aaatattata aaatcactat
     1741 tttttatttc atcttcatat ttttttagat attctaattc tatattctca tttccctttt
     1801 caagttccaa tacataagct ttcccaacaa aattttctat atccaactta tctagggtct
     1861 cacctttagt atacatatgt cttggtgaat ccatatgagt tccattgtga gaaaatacac
     1921 taattaatgt ttcttgataa ccattttctt caataatagc tactttcttg atatctggtc
     1981 tattaggctc tgcatataca ggcatgtcat tatgtgtcac atgagttaaa tcaaaaacct
     2041 tcatctttat atacccccta tgtttttatt ttctattata tacctaaatt cattttattt
     2101 ctatcagatt ttattccatt atataccata ctactatata ttttttataa acctcaaggg
     2161 atttaccgaa aaatcttgga aagaattatc agtaaatata acatcttcac ccaaaaaacg
     2221 tttatacctt ccttcttctt tctttaaagt aattctctgt ttttgtgaat gattattaaa
     2281 aaccattatc ttaagaggag gtttttttct attagtctgc actcttttta acatgtattt
     2341 tatgtgcata tcagcttcag gaaatgaata tccacaaaat attaaaaggt cagtatctct
     2401 taaagttttt tctgtttcat tccaaacatt acttaaaaat atgtttgaca tattcttaaa
     2461 atatgttggt ggcactataa taggttctgt taactcacca cactctaaac attttgtctc
     2521 tgaactattt tcaataagct tcatgacacc accttcatgt ggtgtaagag ttacactatt
     2581 acaaatgggg caataaagcc aattcaatga cccatgtatc ttatataatt tgattaatgg
     2641 ttcttttggt tttctccaat ttaactcctc tttaaaattt gtaaactcca caccataatc
     2701 aagcataatt ggcaaatcat tcttatctct taatccagta actgtattgt ctatatgtat
     2761 atcataattt gcactaataa aagtagtatc aagaagcaaa tcattttcca aaagattttc
     2821 aactaaaagt ttatgatatt tattatctgt tctaggtgta ttatgaattg cttcagccat
     2881 tagcagtatt aaatattgtc ttaaaaaacg tatactatca cttctgttat ttagattttc
     2941 tagtccaaaa tttctaaatg cttcttttct ttgttctgct aagtctaaaa gacctaaaac
     3001 ttcttcaaag gtaggaaaat ttgcattatc tatattatct tttactatat caatattgaa
     3061 catctgttta aagaaaatat acaattctct attcattttg gtattataat ttgtgggatt
     3121 tagtttttta aaatattcgc taaaaagttc attttgaata ggtagattct ctgctgctga
     3181 agctcctgct cctaaaaata ttgctatttt catatagttc ctcctaatat aaatattact
     3241 cctattttta tatccattaa atatccatat catttatttt atgatacaac aataaagctg
     3301 tcttttacta gaaaaaatcc tattacaaga cagccttata ttatattaaa tctttaataa
     3361 ttcgtaaata gaaagagcat atatttgagt agcttttata atatcctcta ctattaagta
     3421 ttcattagct tggtgttctg tttctggttt tcctggaaaa atagctccaa atgcaacaca
     3481 attatctaaa gctcttgcgt atgttgctcc tccagatgaa agtggtgttc catcaagacc
     3541 agtttcttct tcatatactt ttctaagtgt cttaacaaga agagtatctt ctggaacata
     3601 gattgaatcc aagaaatcat attcttcata atttaaattg tatttatctg tcattttctt
     3661 taactctttt acaaaatcat cctttttgta tgttactgga atccttacat ctattcctgc
     3721 aaattctttt tcgttatcaa tagttactct acctatattt actgttagtt tacctgatac
     3781 atcatccttg caattaggaa ttatattgtt tccattagca tcttcaccaa taacttctgc
     3841 taaaaactta attatattag aatctatacc tatattatta agagctatac aaagtctagc
     3901 cactgcattt ataccagtat cacttgctgc tgaatggaca ctttttccaa ttatacagat
     3961 tttattacct tcaacagtat actcaaaatt taatttatca agttcttttt ttaatttatc
     4021 agagtatttt ccaatataga ttgctttacc tggaactgca tttaaagcct ttccaactga
     4081 caactctata tcacttttgc tatcacaagt caaatgaact tgtaaaagac ctttctctgc
     4141 atttgttatt gggaatctag aatctggagt aaatccatag tttggtattt cttcattatt
     4201 ttctttatat ttatttatac atctccaaag attttcttca tcagccccaa aaatgaatct
     4261 tatcctctta ttaaagtcta catttaaatc cataagagct ttcactgcat aaattgctga
     4321 tattgtaggt cctttatcat cttgtgttcc tcttccatac aatttaccat cttctaaaac
     4381 agcttcaaat ggagggtaat tccagctttc taaatcacct tctggaacca catcaacgtg
     4441 accaagtata cctatcattt tttcaccttg tcctatttct gcatatccat aatatccatc
     4501 tttgtatact gtcttaaatc ctaaagattt acataagtct aatatacctc ttaaagcttt
     4561 atctacattt tcaccaaatg ggcaattttc agttgcttca gatataacac taggtatttt
     4621 tacactttct tgtattgaag aaatcatttc atcttgtaga gaatttactt tttctttaat
     4681 ttgctctttc atattatcac ccttcaattt tcatcataat atactaataa atattttgac
     4741 ctttttaaaa aaaaatatgc ttattttttc agttttttta taaattcaat cgcttttaaa
     4801 gtccccattt ttgaatggtc aaatgtaagt ccaccttgaa aataaacatt ataaggaggt
     4861 cttattggag catctgcact taattctata gaagaacctt gtataaatgc tcctgctgcc
     4921 attatgactt cactttcgta tccaggcatg tcccaaggaa caggttttac ataagaatcg
     4981 actggtgcag cttcttgtat accttcacaa aaacttatta cttcatcagc attattaagt
     5041 ctaatacatt gaataatatc acttcttaag tcatcatatt ttggtaatac atcatatcct
     5101 aatttttcaa aagctcttga gcaaaagata gctcccatta cagcctgaga tactatataa
     5161 ggcgccaaga aaaaaccctg aagtacattt ctagttgttc caaaagtaag accacattct
     5221 tttcctattc caggagaagt cattctataa gatataagct caatcaaatc ttttctacca
     5281 gctatatatc cacctgtcaa tgcaagccca ccaccaggat tttttattaa agagccagcc
     5341 ataacatctg ctccaacatc agtaggctct ttggtatcta aaaactcacc ataacaatta
     5401 tcaaccatta ctatagcttc tggtttaaca gactttatta cttctatagc ttcttttata
     5461 tcactaattg aaagtgattt tctccaagaa tatccttttg acctttgtat cataacgagt
     5521 ttagttctat catttatttt gtttttaatt ccttctaaat ctaagtttcc atcctctaaa
     5581 aaatctacat catcatatgt aacaccatac tctttcaatg aacctttttc ttctcttatg
     5641 cctataactc cctctaaagt atcatatggt ctaccagtaa cagataaaat ttcatctcct
     5701 ggtctaacta taccttgtat acataaagta agtgcatgtg taccatttac aattattggt
     5761 cttacaagag catcttctgt attaaatact ttagaataaa tttcctctat tttttcacga
     5821 ccaatatcat tatatccata tcctgtagtc cagttaaagt gcatatcact tagtttagat
     5881 tcttgcatag cttttaaaac tttatattga ttatattctc ttatttcttt tatttcttca
     5941 aacttatctt ttatttcttc cattatttct tgcgatagtt taaaagtatc atcatctatt
     6001 ccatagtagt cttttaataa ttcttttgtc tcattaagca ttttatcacc tgtctcttta
     6061 ttattttatt taaacatgta aaggagacta ttttactaaa acaaataaat tatagtttat
     6121 aagttagtat aagtctcctc tcaatcatct taaattaaat taattatcta tctgttgtta
     6181 ttattattgt tgttttggtt ttgatttgtt agattaatat actttccagg ttgtatagtt
     6241 gatacagcat gtttataaat catgttttgt tgtctattat ccccttctat taatattata
     6301 taactatcaa acccctttac aagcccttta acttgcactc cattaactaa atatatagta
     6361 acaggtatcc tttctttcct tgcattattt aaaaacaaat cttgtaaatt taaaactgta
     6421 tttttcatta gatttgtacc ctcccaagat taaattgaac ttctaaaata ttcctacctt
     6481 atattctata taagttatga caaattttca atattaagtt gtatacttaa aaatttatat
     6541 attattttat agaatcttta atatataaga ttatttcatt ttttaattcg tctatatttt
     6601 catattggtc taaatcaaac catcttgctg ttttatatct tttaaaccat gttatctgac
     6661 gttttgcata ccttctagaa tctcttttaa ttatttcaat agcttcttcg tatgtatatt
     6721 ctccatccag atacttcaat atctctttat aacctatacc ttgcattgat atcatatctt
     6781 ttttaaatcc catacttaaa agttttttta cctcttcaac caatccattt ttaatcataa
     6841 tatcaactct catatttatt ctttgataca aatgttctct atctctattt agaactatta
     6901 ttattggttg atattcttca ttaaatttta aatcacttga aaaatcattc attttcttac
     6961 cacttagaca aacttcaaga gctcttatga cccttttagt attgttttta tggattctat
     7021 tagcagattc ttcatcaagt tcttttaact tattatgcat gtaatctatt cccttttcag
     7081 caagctgttt ttgaagttct tctcttaatt cattattggc atcagattgt gcaaaatcca
     7141 tattatatat taaagagttt aaataaagtc ctgtgcctcc agttactaaa acacattttc
     7201 ccttttcatt tatttcatgt atatattttt ttgctctttg ttgaaactct gaaactgaaa
     7261 atggatagtc aggcttaact tcatctataa ggtaatgctt cactccttgc atttcttcct
     7321 ctgtaacttt tgcacttcca atatccatat attcatatat ttgcatagaa tcagctgaaa
     7381 ttatctctgc atctatatct tttgctaatt ttattgacaa atctgttttt ccaacagcag
     7441 ttggacctgt aagtattata agtggtattt ttttcataac attcctttcc atatatttta
     7501 aatatccaaa tattttacat aattctttta aacatttttt ctatttctgt cttagatatt
     7561 tcgaccatta taggtcttcc atgagggcat gtaaatggat tctcacactt ttctagctgt
     7621 tccaataaac tttttatttc aatatcgtat attttatcat ttgcttttat agcagaccta
     7681 catgccatag atgcaaatct ctctcctttt aaatcataat tacttgtaat ttcttctata
     7741 ttatcaatta tttgaagtat aaatttctca gtttcaggta ctccaaatat agtaggaaca
     7801 catcttacca ttatatgatt attgccaaaa atttctagtt caaaaccaaa tttcataaat
     7861 aactccaagt tattttcaat ttgaagcata tctacatttg atacttcaat aaccactggg
     7921 tctaaaagta tttgcatatt gatatcttgt ctatagaact tctccatata tctttcatat
     7981 agtattcttt catgtgcagc atgttggtcc aacaaataca tagaatcgtc tttgctcaaa
     8041 attatataag tattaaatac aactccaatt acagaatatc catataagga aaacttgcgt
     8101 tttgaactac acaagtattc ttcttcactg tccttaatac tatctcctaa gtaataattt
     8161 ccttcatttt taattccatc aacttgaaac tcttcttgta tattatcatt tgcactatct
     8221 tcacttagat aattaatgtt ttttacatca tcttctacac ttgcatttag gacttcactt
     8281 actgattgaa attcatttat tggtttttca cttgataaag tcacaacttc aatgacttca
     8341 tccttatctt tagtaatatt actattttta ggagtagatt ctaataaatc attatttctt
     8401 aatttataat ctgtactttt ttctctactg ttaatagcga ttctaggttg tgttttttta
     8461 tcactataag tagcatattt tccaataaga tttgagtgta ttaatttaac ctttaaaaaa
     8521 tctctaagtt ctatatacac ttcttgttct ttttcaaatt taatttcaag tttattgggg
     8581 tgtatattta catctataca tgatgggtct acttctatat ttaagaagca cactgcatgt
     8641 ttacctattg gaattataga cttataactt tctgttattg catctatgat tattttactt
     8701 tttacaaatc ttttatttat atagatatgt tgtaagtttt tatttgaacg gtatatattg
     8761 ttattaccta tatatccatt cattttaaag tgattgcact taaactctac atctattata
     8821 ttttccgtta tttcttttcc atatatactt ctaatagtgt ttacaagttt tccatcccct
     8881 ggagtattta acatctgttt attgttattt gtatatttaa attgaatgtt tggattacct
     8941 attgcaagtt tatttatcaa atcacttatg tttatagttt ctgcatgagt agattttaaa
     9001 aatttctgtc ttgctggtgt attaaagaaa atatctttta taatgatggt agttccatta
     9061 gtagaaccta ttggttcttt tgatattatt tttccgcctt caacatatat tttagttcct
     9121 attatttcat ctttagtttt agtcgtcatt tctaattttg atacagctga aatagatgcc
     9181 aatgcttctc ctctaaaacc aagagagtat aaatcataca aatcatcaat ttttttaatt
     9241 ttactagtag catgtctcaa aaatgatttt tcaacttcac ttgaaggtat tcctattcca
     9301 ttatctgtaa tcttaattag actttttcct ccatcaatta tatctatgga aattttattt
     9361 gcacctgcat caatggagtt ttcaataagt tcttttacta cagaagaagg tctttctaca
     9421 acttcacctg ctgctatctt atttatagtc aaatcatcta ggatgttaat tatatttttc
     9481 atttttacac ctctaagatt ttatttcttt tgcttttctt tgaagattat aaagagagtt
     9541 tatagcatct aatggagtca tatttaaaat atccagattt aaaatttctt ctgatagtat
     9601 atctctattt acactatcaa aagagatttg agttaaggct acttctttta cagaatcttc
     9661 ttgattaatt ttctctttat catcattttg cttcattaaa gcaacttcat catttaatgc
     9721 tttaaattta gaatttaatt tatcataatc cttttttata tgtttgtagt cttttactat
     9781 aagttcatgt tctattttta gagattcata tttattctta aaattacttt gatttacctt
     9841 aactaattct tcgtccaaat tactattaat tatattattg ttttctttat ctccatttat
     9901 tgcaacactg ttgtaaacat gatttttttc caagtcttta agtatatatt ttgctctttc
     9961 tatgacttcg tctggtaatt tagctaattt agcaacatat attccataac tcttgtctgc
    10021 tccctgagga attatttttc ttaaaaatat tattccttcc ccatcttctt tgactgctat
    10081 tgaataattt ttaacctctt taaactcttc ttctaaatca gtaagttcat gataatgtgt
    10141 tgcaaataat gtcttacatc taatattttt ttgaatatat tccactattg accatgctaa
    10201 acttatccca tcataggtac tagttccacg acctatttca tctaatataa ctaaacttct
    10261 ctctgttgca ttttttaata taagggatac ttcattcatc tctaccataa aagtagattg
    10321 accttgagat aaatcgtcac tagctccaac tcttgtaaat attctatcta atattggaat
    10381 atcagcagac tctgctggta caaatgagcc tatatgtgcc ataagagcta ttatagcagt
    10441 ttgtctcata tatgttgatt tacctgacat attaggacca gttattatgt taataatgtt
    10501 ttctccacga tttaaataag tatcatttgg aacgaaattc tcctctccta ctatattttc
    10561 gacaacagga tgtctaccat ttcttatatc aagtttatta ttttcattta ttgctggttt
    10621 tacatagtta tttatatgtg caactgttgc aagggacaca aaaacatcta tattagctat
    10681 agtcttagcc actttttgta ttctatctat gtttttatat attgtatctc ttatctctac
    10741 aaatatctcg tattctaaag atttaatctt ttcctctgca tgtagtatct tttcttctat
    10801 ttcctttaat tctggagtta tatatctttc tgcattacta agtgtttgct ttcttatata
    10861 tgtctcatct agctttgcct gtttaaagtt ggcttttgtt atttctatat aatatccaaa
    10921 aactttatta aatcctattt ttaatgattt aactcctgtt ttttctcttt ccctgttttc
    10981 tatttccttt acaagaaagg ctccattctt agaaatctct cttagttcct taagttcatc
    11041 actaaaatct gatttaatta tgtttccatc ttttatggtt atcgtaggtt cttctagaat
    11101 agcttcatct attaaattgt atatatcatc taatttatcc atttctgaaa catactcttt
    11161 taggattttt gcatttgata aatttatagt atcttttaaa ttaggtaact tttctatcga
    11221 attttttaag tgaattaact cttttggtgt tactctctca aatgctatct ttccacatat
    11281 tctttctata tcgtatatat ttttaagtat atcatttagg tcttctctta atataaagtc
    11341 atcttttatt tcttctatta catctaatct attttcaatt ttagatttat ttatcaaagg
    11401 ttcttctaca tattttctta aaagtctacc tcccattgct gtagaagttt tatcaagtac
    11461 atgtaataat gaaccttttt tcttattccc tcttatagtt tgagtaagtt ctaaattagt
    11521 tctagtaaac atatctaaaa ccatatattc tgatgaattg tatatattta tattattaat
    11581 gttagatgtt atttgttttt gagtattgta tatataattc agaagaattg ataagcttga
    11641 ctttattaga cctttatcat caaactttag tttttgtaga taaacatctg gaaaatattc
    11701 ttttaatata tttatatcca aatagttatc actaaaactt tcatttatgt atatattact
    11761 tacagtagct atatctctaa gcttttctat aaagtctaaa tcatttataa ttatttcagt
    11821 tggatggatt tttgcaattt cttcaattac cttatcttca tttaaacatg ttgcattagt
    11881 ttctcctgta cttatatcaa cataagttag acctatatta gtaccatcct tatacaaaga
    11941 taataaataa ttattctttt tattttcaag taaatttcca tctaaaactg taccaggagt
    12001 gatgactctt ataacctctc ttctaacaat tccttttgct gtagatgggt cttccatttg
    12061 ttcacctatt gctactttat atccattttc aactaatttt gatatatatg aattggctga
    12121 gtggaaagga acaccacaca taggagcacg ttcttctaaa ccacaagctt ttcctgtcaa
    12181 tgctatttca agagcttttg aagctactaa tgcatcttca aaaaacattt cataaaaatc
    12241 tccaagtcta aaaaacagta tacagtcttt atatctattt tttacttcaa gatactgttt
    12301 catcatagga gttaatttat tcatatctat ttgcattatc aaacctcctt cttttctaat
    12361 taaatattat atcatagtag atgattatta ttaacacaat atataaaatt ttgacatata
    12421 actaaaaaca atccaaaatg tatactcaca ttttggattg ctaagtttaa tgcttattaa
    12481 ataaaaatat atatattttt acaataaaga tattatttct tttttaagtt taatgatatt
    12541 ttcaaggtta tcttcattta actttctact atctataaca aattctttct ttactattga
    12601 tggttttttt gaaataacat aaattctgtt tgatagcatt atagcttcgt caatatcatg
    12661 agttataaga agtattgttg aatttacttt tttcttaaca tctaaaagcc atttttgcat
    12721 ggatgtttta gttaatgaat caagtgcccc aaaaggctca tctaaaagca ttatgtcatt
    12781 agaatttata aaagttctca agaagttagc tctctgtctc attcctccag aaagttctga
    12841 aggatattta tcttcatatc cgcttaatcc aaacacctca aaataaggtt ttaccattga
    12901 cctagcttta ctcttttttt ctttttttaa aattagtggt agtgacacat tatctattat
    12961 agttttatat ggcaagagta aatctttttg atacatataa ctatatttac catttatatt
    13021 cactttgcca ctatcataat ctgtaagttt agttataata ttaaaaatag tactttttcc
    13081 acatccactt ggccctaata tagaaacaaa ctcaccttca taaacatcaa tacttatatc
    13141 ttttaaaact tcaatatctt tataagtttt tgatacattt tctatagata cttttacttt
    13201 tttattgtgg taaaaattca tttgtgtaag catcacttgc cttcatatcc ttatctatta
    13261 atttatattc ttttaagaat gatgtatagt tgttccatac actatctttc atttctcccc
    13321 atcgtggtgc atcatctttg tacttgcttg ctaaatattc ttgactcttt aaagctagtt
    13381 tttcatctac ttcaggtgca tgttttacta aaatttttgc tgattcttct ggatttttta
    13441 ttgcatattc ataacctttt gttgtagctt ttaagaattt tttagcaagc tctggattat
    13501 ctttaagcac agtttcatta gaaattataa gtggtgtata ataatccaat ctctcatcta
    13561 aatcttttac tggtataaag tttaagtcat atccaattaa atcagcttta actgcatccc
    13621 aaccttcaaa tatccatgca aaatctacag ttttcatagc tgcaaagaaa tcatcttgac
    13681 cagtattaac tatctttaac ttattaaaat cagctccatt tttcttcata actgctttaa
    13741 aaacagcttc ttctgatgga gagccccaac caccataagt ttttccttca aaatctttag
    13801 ctgttgttat attcttttct tttggtgatg caaacccaga agtattatgt tgtataacag
    13861 ttgctacagc ttttattgga agtggatctt cactagtctt tgcataagta acttgttctt
    13921 gatagcttat accaaagtca gcttttcctg ttgctactaa agtttctgct ccactttcag
    13981 gtggttgtac tatttcaaca tccaaacctt cttctttata gtaaccctta tcaagtgcta
    14041 caaataatcc agtatgattt gtatttggtg tccaatcaag caccatagtt acttttttag
    14101 aagaagtatc tttatcattg tttttgtctt tattgttatt tgaagaacat ccagttattg
    14161 ttgccaatgt aaaaacactt actaaaccta atattcctaa ctttttaaaa ttcataattg
    14221 cctccctcaa atacctttaa tcaattaatc tatgtcttat aacaactttt tttacagcct
    14281 gtacaattcc tacaaacatt aaactaaata taactactaa tatagtagat gcaaatactt
    14341 tatcaagtgc atatgcactt tttgacctaa gcatataaac accaagtcct ttcgttccac
    14401 ctagccattc tgcaacagtt gctgccatta cagcatacgt tgcagatatt ttaagtccag
    14461 aaaaaaattt atccattgcc ataggaaatt taaggtgaat gaatgtatta actttatttg
    14521 agtccatagt cttaaataaa tttaaataat ctttatcaat attctcaatg ccatctacaa
    14581 aacttattaa tataggaaaa aaacaagtaa gcattaccat caatactttt ggcattgttc
    14641 caaatccaaa ccatatcata aaaagtggtg ctataattat tgtaggtatc atctgtgtaa
    14701 ccaacataat aggataaaga cattttttta ttattgatac aaaatccatc aatattccaa
    14761 ttaccaatga tattataatt gcgactataa aaccaagtat tgcttctcct atagtaacca
    14821 cagcatgcat ggataaattt tgataatctt taaaaaacac attaattata tctactggtg
    14881 tgggtagtat atactgagga acttctaaaa ctcctaccat agattgccaa agaataagta
    14941 taaacaaaaa tgttgctatt ggatatatac tatctttgac tttatctatg atttctaagt
    15001 ttttcatcta tagtcagacc tccagctttt tcatctactc tagctactgt tatgactctt
    15061 tcacatccaa gattaaaagg gattttatgt acctttttta ataattcaaa aacttcatca
    15121 aaatcacctt caacagtagt gctcattgct cctatttcac atttaagacc acttttttca
    15181 atttcagcaa tacaagcatc tactacttta tacatttctt cttcaccttt gtaaggtctt
    15241 agtggcatta ctgctatgtc tgcgattacc atttaaatca ctcctttaaa aataattaat
    15301 acctactagg tatattttgt tttttattaa aaaattttat tactaaaaag atattatatt
    15361 taaataaaag aaaagtctta tccaaaatag gataagactt atttttatct taactggtct
    15421 ccctacactg gcattatcca aacaggttca aagggtcgag ataaaatctc ctctcagcac
    15481 attagctccc cgaaatatat tatatctttt ctacttgatt atactacact tatcatattt
    15541 taacaaattt tttatttata ttagatattt tatccgttca aaaatatcta atatacattg
    15601 tacattatta caccaaataa attatcttaa aatggtaatt tatcaacatc ttccaaaact
    15661 agattaactg aattttctag tttttatttt gctatttcaa gcatatttgg atgtatatca
    15721 attccataca aatattgttc taaatttctg ttttcactaa tctaatttgc aatcgttaca
    15781 gattacagat tagaaatagc ttttagactc tacttatctt tatctacaaa aaatccttca
    15841 ataaattcag taataatatt cagtaatcta aaaataaacc tctatctgga tttttaagat
    15901 acaagccttt taggaagtat cttttgtgat aatataaaaa ttactcgtca ttatcatcaa
    15961 aatcctcagc aaccaacatt ttagataaga atcaaactct ataatataat tattttatcc
    16021 aatttatttt tgagaaataa aatatttttt taatttttaa attttttaat atgcaccttg
    16081 aaaaaagaaa cgttttccta tattatggta atagtagaat aaaactaaat aggcaaaact
    16141 agagaaattt agtgacgcaa agctataggg actaagactt atgaaatgag ttatgtcagc
    16201 cagttgccaa agagatattt tctttttgtt tttatgaatg ttttttaggg ggatatatga
    16261 tatatgttta tggataaaat ggatagatgt acacatatac taactgcata tatatgcagt
    16321 tcacgcgatt actgcaattt tatagataca caattaaatg attttatact agaatatgga
    16381 gagaatgtgg tagaatcttg tttgcatcaa gtgatggtat tggtaagcag atataattaa
    16441 agaaatttta ttttctagaa aacccttttt agttttatct acgttttata attcattaaa
    16501 gaactaatca aaataagctt cattatatat ttttcatgaa gtaaacagtt gagtttatct
    16561 catatactgt ttaccccaat tacataattc taataatata gattccaatg atttaccacg
    16621 tttagtagac aaatattcaa cttttggagg aatagtcgga taagaaattc tcttaataag
    16681 tccatctctt tcaagatact ttaattcttg tgacagtatc ttatgactta tatgaacaac
    16741 atcttttttt aattgactgt aacgtattgg ctcttgtttt aaaatatgcc ataaaataat
    16801 tgccctccat ttacttccta tcacagtcat ggtaaaacca attgaacaat taaaatcttt
    16861 ttgtctttct tcaatatttg gaaattcttc aaaattatta tctatatcca tctcaatcct
    16921 ctctttcaaa atagtaagta tctaactaaa aagtgcattc ttgtttagcg tactaattcg
    16981 taatataatc ttgattaaaa aatagctacg cacactcgtg actttagtca tgagttagta
    17041 gctaaaatag tcaacatata gggaaac
//
LOCUS       DAMJYN010000080        16443 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.084, whole genome shotgun sequence.
ACCESSION   DAMJYN010000080 DAMJYN010000000
VERSION     DAMJYN010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16443)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16443)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16443
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.084"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(91..1377)
                     /locus_tag="PC466_002898"
     CDS             complement(91..1377)
                     /locus_tag="PC466_002898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDF2770262.1"
                     /translation="MIVGIIGPSDSGFKIKDDLKQIDSDLKTKIYVREKVVDTIEVIS
                     KCEDECDAIIFTGCAVYEFIKSKYEISKPHSFVPRSGTSIMKAFWAIKSANIKLDKFS
                     IDVVDRYVVEDALKEFDIKATSVFCNPFSLEVGESELVEWHIKLFEENKTDIMLTGFG
                     AVYNELKERGYPVFRLQATIQLIKESYDKVKSEYALSKARFSQIAVEILSLIDYKEKI
                     DNYYSDMIKKSDMDKLVVNYVRSIQGSLFLLGRNDYVVFVHKGVADNEYNYDKLFNLK
                     REIKDMGFSLSIGIGTGVTAYQAENNAHKALRHSIDSKEIGIYLVDEDENIRGPLASE
                     NELNYSLMLSDEKVIEISKKTGMSCESVAKIIAISENRKSKIYDSKELAEYLNVSERS
                     ARRILNKIVNAGLGRICAKETSIGGGRPKNITEILF"
     gene            complement(1500..4598)
                     /locus_tag="PC466_002899"
     CDS             complement(1500..4598)
                     /locus_tag="PC466_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HDF2770263.1"
                     /translation="MDVINLIDELDEIVYVSSLDTYELLYINEIGKKAMGINDISHVK
                     CYKALQGKDSPCEFCTNSILKEDEYYIWENTNTRTNRHFILKDKLIKWEGKHARLEIA
                     LDITEKEDISKSIAEKLEIKELLVGCIKHLITESNFSDAVNLVLTNIGKFHKADRAYV
                     FEVSEDRKKVTNTYEWCNEGVDEQKQALTNLDINELKNWFLLFEQKGFVIIDDIENIK
                     EEQPIEYEILKPQKIESLMTSSLKQDDKVVGFIGVDNPHKAVGDTSLLTSLSYFLLTE
                     MKKRKVENKLNYMSYYDFLTGAYNRNKYIKYIDNFQKGKFKSIGVVFVDINGLKDIND
                     NFGHANGDSAIVSACVIIKKYFHSYNVYRIGGDEFIVLCEDISKQLFEELVSWLSEEF
                     KDEMIYSVAVGSIWSDDNIDIHKLIKVADERMYQDKKRYYNKNKLRNNEMEVISDLAD
                     STNNILFKHKELVDKVYFDDLMIKGYSKAYEKLAYNTYDIILSICIDTNLITPIYQSE
                     SNIFSFPIKENLEKTFSYIKKHLIHPDDIILFDDNHLLKSLDSLNNSKQDDLELNFEY
                     RRLGIDKKYYWALIYMLKISSKNKLGEKQTHILVAIKNIDYLMQLHKNQKDILTGLYN
                     YESFCEQTSLMLKRYPDKSYAIIMMDIDKFKVINDIYGVRGGDKALIYVAELIQKNIG
                     SNGICCRMYADVFCIFYESYSDRDVHKLIYKIKNSLNRKKFEYMLVPCFGVYKILDNN
                     IPITNACEMAGYAHKKVKKQSINNYIFYDDTIRNDALEEKQMEREMEYALENGQFHVY
                     LQPKYNLNANKIVGAEALVRWVHPEKGIIPPIKFISLFEKNGFIIRLDMYVWEQVCSL
                     IRKWIDLGEEPVPISVNVSRLHLHNPHFKEIVLSLINKYSIPKSFLELELTESLFIKN
                     IKLFTKIIADLRMDGIVLNMDDFGSAYSSLNMLKNINIDTLKIDCGFFNEEGITDREK
                     IVLRHTIAMAKDLDMDVVAEGVETKEQAEFLVSLDCVVIQGYYYCKPIPSADFEKLLY
                     QK"
     gene            5322..5474
                     /locus_tag="PC466_002900"
     CDS             5322..5474
                     /locus_tag="PC466_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770264.1"
                     /translation="MKIFSFLLFVVGICFCIAGFMGHYPAFAGATLSFFATTMIAVRQ
                     VKTKKK"
     gene            complement(5766..6470)
                     /locus_tag="PC466_002901"
     CDS             complement(5766..6470)
                     /locus_tag="PC466_002901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2770265.1"
                     /translation="MEIKPLVLIVEDDKPICKFIKVSLETQNYRCVETDNGGTAISLI
                     HSLDPDLIILDLGLPDIDGIEVIGRVRACAKTNKIIVVSAREHERDKVEALDGGADDY
                     LTKPFSVTELLARVRVALRNKAQQDNINNDAPKSFEVKNLKIDYENHIVSINGEEIHL
                     TPIEYKIIELMSKYSGRVLTHKFIIDKVWGNYYESENQSLRVFMASIRRKIEKNPAQP
                     EYILTEVGVGYRMADE"
     gene            complement(6461..8068)
                     /locus_tag="PC466_002902"
     CDS             complement(6461..8068)
                     /locus_tag="PC466_002902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4118 domain-containing protein"
                     /protein_id="HDF2770266.1"
                     /translation="MKKERLQHEDLKEYDYDEDGYLSKKIIIKDFIKTILVMTIATGI
                     SVVFEKVGFNESNIILVYILGVLFATSITYGYFFGILSSVIGVLSFNFFFTHPLYTFL
                     AYRKDYPMTFCIMLMAAIITSTLTSRIKREVRLSHKREKMIRLLYENNKTLLKAKNKN
                     QIIEFCGSNLVNILNRTVIVTIADENNNLGKPSIYICNNDGSENIFHSVLEKEAIKEA
                     FRTGNPVGIGTKYCKNSSAYYFPIKGQESNVLGVIGVACFKIDIITENEKILLEAVST
                     QVALAIDRENLFEKNKKANLEAERERLRGNLLRSISHDLRTPLTSILGSSSTILENDD
                     VIDKETRVELLKNIYEDTSWLTHSVENILSMTRIDEGKLDIEKRPEVVDEIIAESILR
                     VKKFANSRDIKTNIPDEIIIVHVDVLLIEQVLVNLIDNAIRHTPKNSKIELTVKKESN
                     QVLFEVADNGKGIPNEDIGNIFNRFYTKNKSRNLERRGIGLGLEICKSIVEAHGGEIV
                     AFNNPSGGATFRFSIPMYDEEGKDKWK"
     gene            complement(8322..9500)
                     /locus_tag="PC466_002903"
     CDS             complement(8322..9500)
                     /locus_tag="PC466_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770267.1"
                     /translation="MEKLSDKRRVKAVSMETFVFIVLLAVGFGYVGSIMGAGMMFKVI
                     MSTAHALLLDTVFLIMAMAVLAGALSALLSEFGVISLVNKIFKGLMRPIWGLPGASIA
                     GVVATYLSDNPAIIPFAKDKTFTQYFKKYQVPALCNLGTAFGMGLIVTTFMIAQGKEY
                     VLPAIIGNVGAIIGSIISVRIMLTFTKKYYNYDPKNDTEKQINDKGAKLEEFREIRDG
                     NVFQRTLDAILEGGKLGVEMGMAIIPGVLVVCTLVMLLTFGPSTDPATGQAVYTGAAY
                     EGIKLLPAIGDKISFIIEPLFGFTSPEAIAFPVTALGAVGAAISLVPEFIKSGAITPN
                     DIAVFTAMGMCWSGYLSTHIGMMDALDARPLAGKAILSHTIGGLCAGICAHFIFMLVG
                     "
     gene            complement(9726..10220)
                     /locus_tag="PC466_002904"
     CDS             complement(9726..10220)
                     /locus_tag="PC466_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HDF2770268.1"
                     /translation="MHLFIEVIAAFFTALSFGVLFNMKGKNLILAGIGGSIAWFSYKF
                     LLNMGVTENLCFFIATVCFAIYCELCARIYMTPATTLSVCCLIILVPGYGIYNTMYSV
                     LTNNYIKAVEYGVSTLSCASSIALGLVFITTVFRKVNLYGVLTKIKENEKYKKSINKI
                     KQQK"
     gene            complement(10221..10982)
                     /locus_tag="PC466_002905"
     CDS             complement(10221..10982)
                     /locus_tag="PC466_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HDF2770269.1"
                     /translation="MDIDRILNFSSNAGKAMLQSGGETYRVEETIARICQSFGIDHVD
                     VFATPTAVMASVFVDGKLHSAIKRISSRRVDLNLVHEVNSLSRAISINNLDIELCEKI
                     LDEISEDNYYSDLITIFFAGIAAATFSILFGGNVEEFIAAFTVGILTKFVIMYLSKSS
                     LNDFFVNAIGAVIIASCSILILKLGFIKTLDHLIAGAIMLLVPGLALTNALRDLLDGQ
                     LISGLAKLAEVFFVGVSIAVGMFLVLGLYFKLGGI"
     gene            11705..14539
                     /locus_tag="PC466_002906"
     CDS             11705..14539
                     /locus_tag="PC466_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2770270.1"
                     /translation="MLRKDKVLLSLHKLCENMTLKDLQSDKTGFTTIEIANHSSLDRS
                     NTSKELNNLYNEKKVLKISGKPILFLHVSIIENLIGRTLNSDEFSINNCNELLKSSKN
                     DSEDIFSTLLGHDSSLKLPIEKAKSAILYPPKGLNTLLIGPTGVGKSTFAETMYKYAV
                     ESKIFSSESKFVVFNCAEYAENANLLLSNLFGYVKGSFTGANKDKFGIVAQADGGILF
                     LDEIHRLPPEGQEMLFLLMDKGIYRRLGESDIVHKANVFIVCATTEDIHSSLLGTFLR
                     RIPVTINLPALQDRSLKERLSLIKYFFIIESKYTNATIKVHKDVIKSLLLYDCFGNIG
                     QLKSDIQLMSARAFLNYKTGLKDNIEIDLSLVPDYIYIGLLKLNENRSNLNKLSELDY
                     MLFYEFNGNNLEVEYTKELSKYNIDTSNNGFKYSTEIPYLENDIRSMFINYMEKYSTK
                     LLSISSVTHSDYTSNEIFKVINPKIYYAVEHSLKEAEKISRNKYTKQTYIALSMHISA
                     LIENINQDTYNPKYNLYNDKIFLDKDLNISKIVLSIIENDLQTSLPKDEVKFISMFLN
                     SMYLEPNNQSESIGVIILAHGNSTASSMCDVANSLLGTNHCNAIDMPLDVKVSTILDK
                     TIELVKECDEGKGVLLLTDMGSLIAFGELISEKTKIKTRSIEMVSTPIVLEAVRKSTL
                     PEMTLDELANSLSSLNPYIGRAAIDSTEINYPEKSREYVIITTCITGYGSAMKVADFI
                     NSSLKNIRKYNINLVPHNIESFKMYKNKFSNTKILAVVGSVDFNVANTPFIHIEELLN
                     GYGLDMLNKIIEGTFNANSITNIKETNLSYNSLIINFMTQNLELLDSVKLFNYVNSSL
                     FTIIELIDENLKSKFKLGYILHCSFMIERCFKNTTFPYNNITELISKNHELYSLIREA
                     FKPTEAYFNILIPDEEIAYIIDMINEYLNK"
     gene            14582..15826
                     /locus_tag="PC466_002907"
     CDS             14582..15826
                     /locus_tag="PC466_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HDF2770271.1"
                     /translation="MEDEILKGKIKQLTILALIFIFITPVFAFADTPPVPNSSRAALL
                     IDQETKRILFEKNIDEKMPLASLSKMMTFLLAIEAVDKNQVKETDMVKIDKSTASVGG
                     STCKLKDGDEISLGELMQGLMLVSGNDAAIAIAKHIGKTEKNFVNMMNKKAEEIGMID
                     TYYFNPNGLPIYTDPEHKEPPIENMSTAHDIVTLGKYMYDHYENQVTRITTMQVYNDT
                     KKDFTHYNTNPLLVSVPGVDGIKTGYTDNAGYCLAFSMMVPKDAKNERNHRLIGVVLG
                     DGNKKNRISSSATLLKYGKDNFHSKKIAHKGDIIETPCVDGIDDFKITVKVDKDLYGV
                     VSDNENINPKVVFKNMNYPIHKGDIVGVAKYYNDSGKFVGSVDVKSESNIGCIPLKDK
                     IKIKVAKINKKLEIKNSVCFKV"
     gene            complement(16267..>16443)
                     /locus_tag="PC466_002908"
     CDS             complement(16267..>16443)
                     /locus_tag="PC466_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FIVAR domain-containing protein"
                     /protein_id="HDF2770272.1"
                     /translation="TYKTAIDEAQAILDKADATQKEIDDAVTALNTATATFEAGKVPT
                     TIALMLSRILGFMK"
BASE COUNT         5730 a         2727 c         1880 g         6106 t
ORIGIN      
        1 tttttttcat gataagcttt aatactttat atagtaattt gttgtagaat tttataaaat
       61 ataatgattt atacagtttt ataaaatatc ttaaaacagt atttcagtaa tattttttgg
      121 tcttcctcca ccaatactag tctcttttgc acatattcga cctaaacctg catttactat
      181 tttatttaat atacgtcttg cacttctttc acttacattt agatactctg ctaactcttt
      241 tgaatcataa atcttacttt ttctattctc acttatagca ataatttttg caactgactc
      301 acaactcatt ccagtctttt tagatatttc tattaccttt tcatcagata gcatcaaaga
      361 ataatttaat tcattttcgg aagctaaagg tcctcttata ttttcatctt catctaccaa
      421 atatatacca atttcttttg aatctatgga gtgtcttaat gctttatgtg cattattttc
      481 agcctgatac gcagttactc cagtaccaat tcctatacta agagaaaagc ccatgtcttt
      541 tatctctctc tttagattga atagcttatc ataattatac tcattatcag ctaccccttt
      601 atgaacaaat acaacataat catttcttcc aagtaaaaat aaggaacctt gaatgcttct
      661 tacatagttt actacaagct tatccatatc tgattttttt atcatgtcag aataatagtt
      721 atctatcttc tctttataat ctattagact caatatttcg acagcaattt gagaaaatct
      781 tgccttgctt agagcatatt cactctttac cttatcataa ctttctttga ttaattgtat
      841 agtagcttgt aaacgaaata caggatagcc tctttctttt aattcattat atactgcacc
      901 aaaaccagtt aacattatat ccgtcttatt ttcttcaaat aattttatat gccattctac
      961 aagttcagac tctcctactt ccaaagaaaa tggattacaa aatacactcg ttgctttaat
     1021 atcaaattct ttaagtgcat cttccacaac atatctatca actacatcta tactgaattt
     1081 atctaatttt atatttgcac tttttattgc ccaaaatgcc ttcattatac tcgtcccact
     1141 tctcggtaca aatgaatgtg gcttacttat ctcatactta gattttataa attcataaac
     1201 tgcacatcct gtaaatataa tagcatcaca ttcatcttca catttagaaa taacttctat
     1261 tgtatctact actttttctc ttacatatat tttagtcttt aaatcactgt ctatctgttt
     1321 taaatcatcc tttatcttaa acccagagtc tgaaggacct ataataccca ctatcataaa
     1381 cttcgctcct aatccataaa tattatactt tttaaaaatt atatcctcac tattttctac
     1441 ttctatttaa ttatgttgaa ctactccatc ctacctacat ttagagtggg ataattagct
     1501 tatttttgat aaagtaactt ctcaaaatca gcacttggaa taggcttaca ataataataa
     1561 ccttgaatta ccacacaatc taaactcact aaaaattcag cttgttcttt tgtctctaca
     1621 ccttctgcca ctacatccat atctaaatct tttgccatgg ctatagtgtg ccttaaaact
     1681 attttttctc tgtctgtgat tccttcctca ttaaagaagc cacaatctat cttcaatgta
     1741 tcaatattaa tattttttaa catatttaat gaagaatatg ctgaaccaaa gtcatccata
     1801 tttaaaacaa taccatccat tctaaggtcg gctattatct tagtaaataa ttttatattt
     1861 ttaataaata aactttctgt aagctccaat tctaaaaaag attttggtat actatattta
     1921 tttattaaac ttaaaacaat ttctttaaaa tgtggattat gcaaatgtaa tcttgataca
     1981 tttacagaga taggaactgg ctcttcacct aaatctatcc attttctaat caaagaacat
     2041 acttgttccc acacatacat gtctaatctg ataataaacc cattcttctc aaatagtgaa
     2101 ataaatttaa ttggaggtat tatacctttt tctggatgaa cccatctaac caatgcttcc
     2161 gcaccaacaa ttttatttgc attaagatta tacttaggtt gtagatatac atggaattgc
     2221 ccattttcaa gtgcgtattc catttccctt tccatctgtt tttcttcaag tgcatcattt
     2281 cttatagtat catcataaaa tatatagtta ttgatacttt gtttctttac ttttttgtga
     2341 gcatatcctg ccatttcaca cgcatttgta attggaatat tattatccaa aattttataa
     2401 accccaaaac atggtactaa catatattca aatttttttc tatttaagct atttttaatc
     2461 ttataaatta atttatgaac atctctatca gagtaactct cataaaaaat acaaaataca
     2521 tctgcataca tacgacaaca tataccatta gaaccaatgt ttttttgaat caattctgca
     2581 acatatatta aagccttatc tcctcctcta actccataaa tgtcattaat taccttgaac
     2641 ttatctatat ccatcattat aattgcatag ctcttgtcag gatatctttt aagcattaaa
     2701 cttgtttgtt cacaaaaact ttcataattg tatagtcctg ttaatatatc cttttggttt
     2761 ttatgtagtt gcataagata atctatattt tttatagcaa ctaaaatatg tgtttgtttc
     2821 tcacctaact tatttttact actaatcttt aacatataaa ttaatgccca atagtacttt
     2881 ttatctattc ctaaacgtct atactcaaaa tttagttcta aatcgtcttg cttgctgtta
     2941 ttaagactat caagagattt tagaaggtgg ttatcatcaa ataatattat atcatcagga
     3001 tgaattaaat gtttttttat gtatgaaaaa gttttttcaa gattttcctt tataggaaaa
     3061 ctaaaaatat tgctctctga ttgataaatt ggagtaatta aattagtatc gatgcaaata
     3121 gataaaatta tatcatatgt attataagct aatttttcat aagccttaga ataccctttt
     3181 atcattaaat catcaaaata aaccttatca actaactctt tatgtttaaa taaaatatta
     3241 ttcgtcgaat cagctaagtc actaattact tccatttcat tatttctaag tttgttctta
     3301 ttataatacc tcttcttatc ttggtacatt ctctcatcag caactttaat tagcttatgt
     3361 atatcaatat tatcgtcact ccaaatactg cccactgcta cactatatat catctcatcc
     3421 ttaaattctt cacttaacca actcactaat tcttcaaata gttgttttga tatatcttca
     3481 cataatacaa taaactcatc tcctccaata cggtaaacat tataagaatg aaagtatttt
     3541 tttattatta cacatgctga cacaatagca gagtcgccat tagcatgtcc aaagttatca
     3601 ttaatatctt ttaacccatt tatatctaca aatacaactc ctatggattt aaattttcct
     3661 ttttgaaaat tatctatata cttaatatat ttgtttctat tatatgcacc agtcaagaag
     3721 tcatagtagc tcatataatt taatttattt tctacttttc tttttttcat ctcagttaat
     3781 aaaaaataag atagggatgt caaaagagag gtatctccaa cagccttatg tggattatca
     3841 actccaataa accctactac tttatcatct tgttttagtg aagatgtcat taaactttca
     3901 attttttgag gttttaaaat ttcatattct attggctgtt cttcttttat attttctata
     3961 tcatcaatta ttacaaaacc cttttgttcg aataataaaa accaattctt taattcatta
     4021 atatcaagat ttgttagtgc ctgtttttgt tcatcaacac cttcattgca ccattcatat
     4081 gtattagtta ctttttttct atcttctgat acttcaaaaa catatgctct atcagcttta
     4141 tgaaatttac caatattggt taatacaaga tttacagcat cagaaaaatt agattctgtt
     4201 ataagatgtt taatacatcc aactaataac tcctttatct ctaatttttc tgctattgac
     4261 ttacttatat cttccttttc tgtaatatca agagctattt ctaatcgtgc atgtttgccc
     4321 tcccatttaa ttaacttgtc ctttaatata aaatgtctat ttgttcgagt attcgtattt
     4381 tcccatatgt aatattcatc ttcttttaaa atagagtttg tacaaaattc gcagggagaa
     4441 tctttcccct gtaatgcttt ataacatttt acatgggata tatcattaat tcccattgcc
     4501 tttttcccaa tttcattaat atataaaagt tcatatgtat ctaaagaaga aacatataca
     4561 atttcatcca actcatctat taaatttatt acatccattt atatatatct ccttttattc
     4621 attttccaga ttgaattttt aaagctttta aaattttgct atatatttgg caatgatatt
     4681 atacttcttt atgttttaaa atagtacctt aataaagttc tattttttag taaatagaat
     4741 tattattgtg tcaatcgtac aatagagttt tgtaatacct aatttaatat atttataatt
     4801 aactatctta ttatgtgttt acaattaatt ctcatataaa tgacaaatct ccacctcaat
     4861 taagtattcc aatcatatat gaagataata cttcattcat ttaaaaatat aaaactatta
     4921 tatattaaaa tttcttcaat aataaattat ctagattgtt actttgatat attatataat
     4981 atcacaaagg ctgatataaa aagacaaaaa gggtaatttt tttatatcaa aaaaaatgtt
     5041 aaattgatat tatccatata taaattgata ttatccatat agatgctata tttaacaatt
     5101 ctacttactt cccttacact tattagcata tagttattaa gagtttgttg caaaacaaca
     5161 cttagcacac tttaaaaagt gtggtctaat aagtaatcaa cgaagaagac ataataaagc
     5221 ataaaatatg atatactttt cctgtcatca aaactgatga ttttactatt aatatctgct
     5281 aaaatatgct taataaatta aattttagtg ggagaatagt tatgaaaata tttagtttct
     5341 tgttgtttgt agtgggaata tgtttttgta ttgctggatt tatgggacat tacccagcat
     5401 ttgctggtgc aacattgagt ttttttgcaa ctacaatgat agctgtaaga caagtcaaaa
     5461 ctaagaaaaa atgaaatagg caaatcctaa ctttacaagt taatattaca taagtaatta
     5521 gtctaaaatt ggatactttt tctattacag aaatacatca tccactttgt attctcttaa
     5581 aaaaataaaa tagctatgta aattcaagat tagatagatt aactctctat ccatttcatt
     5641 gtaaaatata catagctatt tgtattcgat ttaaaatact tagattttct tacataacaa
     5701 ataatttcta tctgattatt actcatattc atttagtaat cactcagcaa ctaatcattt
     5761 agtatctatt catccgccat acggtaacct accccaacct cagtcaaaat atattctggc
     5821 tgagcaggat tcttttcaat tttccttctt atacttgcca taaaaactct aagcgactga
     5881 ttttcacttt catagtaatt tccccaaact ttatctatta taaacttatg agttaagact
     5941 cttcctgaat acttagacat caactcaata atcttatatt cgattggagt taaatgtatt
     6001 tcttcaccat taattgacac aatatgattt tcataatcta tctttaggtt tttaacttca
     6061 aaagactttg gagcatcatt atttatatta tcctgttgag ctttatttct aagagccaca
     6121 cgtactctag ccaaaagctc tgttacacta aaaggtttag ttaaataatc gtctgctcct
     6181 ccatctaaag cttccacctt atccctctca tgctctctcg ctgaaacaac aattatttta
     6241 ttagtctttg cacatgccct aactcgtcct attacctcaa tcccatcaat atctggtagt
     6301 cctaaatcca aaattatcaa atctgggtca agagaatgta taagtgatat agctgttcct
     6361 ccattatctg tctctacaca cctataattt tgagtttcaa gagatacttt tataaattta
     6421 caaattggct tatcatcttc tacaattaga actaatggct ttatttccac ttgtctttcc
     6481 cctcctcatc atacataggt atgctaaatc taaatgtagc tcctccagaa ggattattaa
     6541 atgcgacaat ttctccacca tgagcttcta ctatagattt acatatctcc aatccaagac
     6601 caatacctct tctttcaaga tttctagact tattcttagt ataaaaccta ttaaaaatat
     6661 taccgatatc ttcatttggt attccttttc cattatctgc aacttcaaat agcacttgat
     6721 ttgactcttt ttttacagtt agttctatct tagaattttt aggtgtatgc cttatagcat
     6781 tatcaattaa atttactaac acttgttcta ttaataatac atccacatga acgattatta
     6841 tctcatctgg aatattggtt tttatgtctc tactattggc aaactttttg actcttaata
     6901 tagattcagc tattatttca tcaacaactt ctggtcgttt ttcaatatcc aatttccctt
     6961 catctattct agtcatacta agtatattct caacagaatg agttagccaa ctcgtatctt
     7021 catatatatt tttcaataat tctactctag tttctttatc tatcacatca tcattttcaa
     7081 gtattgttga agacgaaccc aatatacttg taagtggagt tcttaaatca tgagaaattg
     7141 acctaagcaa atttcctctt aatctctctc tctctgcctc aagatttgct tttttatttt
     7201 tctcaaataa attttctcta tcaattgcca acgcaacctg tgttgaaact gcttctaata
     7261 gtatcttttc attttctgta ataatatcta tcttaaaaca cgcaacacct ataacaccaa
     7321 gaacatttga ttcttgacct tttataggga aataatatgc actgctgttt ttgcaatatt
     7381 ttgtcccaat tccaactggg ttacctgtcc taaaagcttc ttttatagct tctttttcta
     7441 atactgaatg gaatatattc tcacttccat cattgttaca aatataaata cttggcttac
     7501 ctagattatt attctcatct gcaatagtca ctattacagt tctatttaat atatttacta
     7561 aattagaccc acaaaattca ataatttgat ttttattttt tgctttaagc aacgttttgt
     7621 tattctcata gagcaatctt atcatttttt ctctcttatg agaaagtctc acttctcttt
     7681 ttatcctaga agttaaagta cttgttataa ttgctgccat tagcataata caaaaagtca
     7741 taggataatc ttttctataa gctaaaaaag tatataatgg atgcgtaaag aaaaaattaa
     7801 atgatagcac tcctattact gaagaaagta ttccaaaaaa atatccatag gttatacttg
     7861 tagcaaatag tacacctaat atgtatacta gtataatatt agattcatta aaacctacct
     7921 tttcaaaaac tactgatatt ccagtagcaa ttgtcataac caatatagtt tttatgaagt
     7981 ccttaataat tatcttttta ctgagatagc catcttcatc ataatcatac tcttttaagt
     8041 cttcatgttg tagtcgttcc tttttcattt actacaattc ctccttattg ttactgttta
     8101 aattggctct attttatata atacaatttt atcataataa attcaatcaa tacatttaat
     8161 taatgtactt aaattactaa aaggtgctgt cttaaaatga aaataaatct ctatttcaaa
     8221 acagcaccta tatatttaaa ttactaattt agtttttaca tacttaaatc aatagtttta
     8281 ttcaatttta taaattataa tacttcaatt atggaacatt tctatccaac aagcataaat
     8341 ataaagtggg cacatatacc tgcacacaaa ccacctatgg tatgcgaaag tatcgcttta
     8401 ccagccaatg gtcttgcatc taaagcatcc atcataccta tgtgtgtact taaatatcca
     8461 ctccaacaca tacccattgc tgtgaatact gctatatcat taggagttat agcgcctgat
     8521 tttataaact ctggtactaa agatattgct gctccaacag ctcctaatgc agttacaggg
     8581 aatgctattg cctctggtga tgtgaatcca aataatggtt ctattatgaa gctaatctta
     8641 tcaccaatag caggtaataa ttttatacct tcatatgcag ctcctgtgta aacagcttga
     8701 cctgtagcag ggtctgtaga tggtccaaaa gttaataaca taactaatgt acaaactact
     8761 aaaactcctg gtattatagc catacccatt tcaacaccta gcttaccacc ttcaagtata
     8821 gcatccaatg ttctttggaa tacattacca tctcttattt ctctaaactc ttcaagtttt
     8881 gcacctttat catttatttg cttttcagta tcatttttag ggtcataatt ataatacttt
     8941 ttagtaaaag tcaacataat tctaacacta ataatactac ctattattgc cccaacatta
     9001 cctattatag ctggtagtac atattcttta ccttgagcta tcataaaagt tgttacaata
     9061 agtcccatac caaaggctgt tcctaaatta cataaagcag gtacttgata cttcttaaaa
     9121 tattgtgtaa atgttttgtc tttagcaaat ggtataatag ctggattatc agataaatat
     9181 gttgcaacta ctcctgctat actagcacca ggtaagcccc atataggtct cataagaccc
     9241 ttaaatatct tattaactaa agatattact ccaaactctg aaagcaacgc actaagtgca
     9301 cctgcaagaa ctgccatagc cattattaaa aatactgtgt ctaataaaag cgcatgtgct
     9361 gtactcatta ttactttaaa catcattcct gcacccatga tgcttcctac atatccaaat
     9421 cctaccgcca atagtacaat aaatacgaag gtttccatac ttactgcctt gactcttctc
     9481 ttatccgaca gcttttccat cttgaaatct tccccctttt aattttaaat taaggttcct
     9541 aacattggta caaatttttt ggtacaaact gagttctaaa acttacactc gtaatgcaag
     9601 ttgtcagttt tttgaaataa aaaaaaatta cgtttataga ataagaatat cctctttaat
     9661 ttggatactc ttattctatt ttatgttatt atattatcat ccttttgttt aaaagtcaat
     9721 tttttctatt tttgttgttt aattttattt atactctttt tatatttttc attttctttt
     9781 atctttgtaa gcactccata taagttgact tttctaaata cagtagttat aaataccaat
     9841 cctaatgcaa ttgaacttgc acatgataat gtactcaccc catattctac agcttttata
     9901 taattattgg tcaaaacaga atacatagta ttatatattc cataaccagg tactaatatt
     9961 attaaacaac aaacacttaa tgtagttgct ggagtcatat aaattcttgc acataactca
    10021 caatatatcg caaaacaaac tgtagctata aaaaaacata agttttctgt tactcccata
    10081 tttaaaagaa atttatatga aaaccaagct atacttccac ctattcctgc tagtattaag
    10141 ttttttcctt tcatattaaa tagcactcca aagcttaagg cagtaaaaaa agctgctatt
    10201 acttctataa acaaatgcac ttatatcccc cctaacttga agtataatcc aagtaccaag
    10261 aacattccta ctgctataga tacacctaca aaaaatactt ctgctaattt tgcaagacca
    10321 gaaatcaact gtccatctaa caaatctctt aatgcattag tcaaagcaag cccgggaact
    10381 aagagcatta ttgctcctgc tattaaatgg tctaacgtct ttataaatcc gagctttaaa
    10441 attaaaattg aacaagaagc tataataact gctccaattg catttacaaa aaagtcatta
    10501 agtgaagatt tacttaaata cataataaca aacttagtca gaatcccaac agtaaatgca
    10561 gctataaatt cttccacatt tcctccaaat aatatcgaaa aagttgctgc tgcaatacct
    10621 gcaaaaaata ttgttattaa atccgagtaa tagttatctt cacttatttc atctaaaatt
    10681 ttctcacata attcaatatc taaattattt atacttattg ctcttgataa tgagttaact
    10741 tcatgaacca agtttaggtc tactcttctt gagcttattc ttttaattgc tgaatgtaat
    10801 ttcccatcta caaatacaga tgccattaca gctgttggag ttgcaaatac atctacgtgg
    10861 tctattccaa aagattgaca tattctagct atcgtttctt caactctata ggtttctcct
    10921 ccactttgca acatagcttt acctgcattt gaggaaaagt ttaaaattct atctatatcc
    10981 acaaaacata tctcccattc ttttatagta ttattcatat tttaatacaa gatattattt
    11041 atttaaacta ttttaaataa ttcatatcca atatttacat tttatgaaaa aacttgtttt
    11101 ttatgcttgt caaaatcaaa ttttaagctt gtttacacca taaaatggct gaattaatat
    11161 ttgacaaaca ctttcaacca tttatataac cttctaaatt gtataacttt ttactacaaa
    11221 taaaattata tctcttttaa ttctttctct tgagtattta agcttatagc aacttcatat
    11281 ttatatatgt acaatataaa acattatttt tatgatacaa aatataattt gtaaacgtat
    11341 atatgtatta actgtgtata tataaattat tcttaacctt atcagttttt tcatatatct
    11401 tcatctatat cgaccatata ttaattacat tgaccatata ctaataaatg atattacata
    11461 gactgaagta tattaaaaaa cttaaattta gttatttaac aacataatac tctaatttaa
    11521 tctataaaaa tccataccta atataatgca actcttattt taacaccatc tattacacaa
    11581 aacaacatat taaaaagtaa aatacaaaat atccactata aaccttattt taatactgaa
    11641 tatatattat aatatattta atgtagctta aatatagttt aaacataaag aaaggaaatg
    11701 gtatatgcta agaaaagata aagttctatt atctctacat aaattatgtg aaaatatgac
    11761 tttaaaagac cttcaatcag ataaaacagg attcactaca atagaaattg ctaaccattc
    11821 atctcttgat agaagtaata ccagtaaaga attaaataac ctatataatg aaaaaaaagt
    11881 tctgaaaata tctggtaagc caattttatt tctacatgtt agtattatag aaaatttaat
    11941 tggccgtact ttgaacagtg atgaattttc tataaataat tgtaatgagc tacttaaatc
    12001 aagtaaaaat gactcagaag atattttttc aacattactt ggacatgatt ctagtcttaa
    12061 actacctata gaaaaagcta aatctgctat actctatcct ccaaaaggtc ttaatacgtt
    12121 actcatagga cctactggtg ttggaaaaag tacatttgcc gaaacaatgt acaaatatgc
    12181 tgtagaaagt aaaatctttt cttctgaaag caaattcgta gtatttaact gtgctgaata
    12241 tgcagaaaat gctaacttat tattaagtaa tttatttggt tatgtcaaag gttcttttac
    12301 tggtgctaat aaggataaat tcggcatagt tgcacaggct gatggaggca tattattctt
    12361 agatgaaata cacagattac caccagaagg tcaagagatg ctttttcttt tgatggacaa
    12421 aggcatatac agacgattag gagaatctga cattgtgcac aaagctaatg tctttattgt
    12481 gtgtgccaca acagaagata tacattcttc tctgcttggg acttttttaa gaagaatccc
    12541 tgttacaatc aacctacctg ctttacagga taggtcttta aaagaaagat tatctcttat
    12601 taaatacttc tttattatag aatcaaaata caccaatgca actataaaag ttcacaaaga
    12661 tgtaattaaa tcattactcc tttatgattg ttttggtaat ataggtcagc ttaaatctga
    12721 catacaactt atgagtgcaa gagccttttt aaattacaaa actggactta aggataatat
    12781 agaaatagat ttatcccttg ttcctgatta catctatatt ggtcttttaa aattgaatga
    12841 aaatcgtagt aatctaaata aattatcaga acttgattat atgctttttt atgaatttaa
    12901 tggtaataac ttagaagttg aatatacaaa agaactatct aaatacaata tagatacatc
    12961 aaacaatgga tttaaatact ctacagagat tccttatctg gaaaatgata taaggagtat
    13021 gtttataaat tacatggaaa agtactctac aaaattactt tcgatatctt cagtaactca
    13081 ttctgattat acaagtaatg aaatttttaa agtaatcaat ccaaagattt actatgctgt
    13141 tgaacattct ttaaaagagg ccgaaaaaat atcgagaaac aaatacacaa aacaaactta
    13201 tattgctctt tcaatgcata taagtgcact tatagaaaat ataaatcaag acacctataa
    13261 tcctaagtac aatttatata atgataaaat tttcttagat aaagatttaa atatatctaa
    13321 aatagtttta agtataattg aaaatgactt acaaacatct ttacctaaag atgaagtaaa
    13381 atttatatcc atgtttctaa atagcatgta tcttgaacca aacaatcaat ctgaaagtat
    13441 aggagtcata atacttgctc atggaaattc aacagcaagc agtatgtgtg atgtagcaaa
    13501 ttcattgctt ggtacaaacc attgtaatgc aattgacatg cctcttgatg taaaagtaag
    13561 taccatactt gataaaacta tagagttggt aaaagaatgt gacgaaggta agggtgtact
    13621 tcttttaaca gatatgggct ctcttatagc ttttggagaa cttatttcag aaaaaacaaa
    13681 aatcaaaact cgctcaattg aaatggtatc tactccaata gttttagaag cagtaagaaa
    13741 aagtacatta ccagaaatga ctttggatga attagctaat tccttaagct ctttaaatcc
    13801 atatattgga cgagcagcaa tcgattcaac agaaataaac tatcctgaaa agtcaagaga
    13861 gtatgtaata ataactactt gtataacagg atatggttca gctatgaaag tagcagactt
    13921 tataaattct tcacttaaaa atattcgtaa atacaatatt aatttagttc ctcataatat
    13981 agaaagtttt aaaatgtata agaataaatt tagtaatact aaaattctgg cagttgttgg
    14041 aagtgtagat tttaatgtag ccaacacccc ttttatacac atagaggaat tactaaatgg
    14101 atatggccta gatatgctaa acaaaataat agaaggtaca ttcaatgcca atagtattac
    14161 aaatataaaa gaaacaaatc tatcatacaa cagtttaata ataaacttta tgacccaaaa
    14221 cttagaactt ttggactctg ttaaattatt caactatgtc aattcttcct tatttacaat
    14281 aatagaatta atagatgaaa acttaaagag caaatttaag ctaggatata tactacattg
    14341 ctcttttatg atagaaagat gttttaaaaa tacaactttt ccatataata acattactga
    14401 attaattagt aaaaatcatg aactatatag tttaatacgt gaagccttta agccaacaga
    14461 agcttatttt aatattttga taccagacga agaaattgct tatataatag acatgattaa
    14521 tgagtatcta aataaataaa atttatagca cttattttgt gcatattaat taatatatga
    14581 aatggaggac gagattttga aaggaaaaat aaaacagtta acaatacttg cattaatttt
    14641 tatatttata actcctgtat ttgcatttgc agatactcca ccagtaccaa attcttcaag
    14701 agcagcacta cttatagacc aggaaactaa aagaatatta tttgaaaaaa acattgatga
    14761 aaaaatgcca ttagcgagtt taagtaaaat gatgaccttt ttattggcaa tagaagcagt
    14821 tgataagaat caagtaaaag agactgatat ggtgaaaata gacaagtcta cagcttcagt
    14881 aggaggttct acttgtaaac ttaaagatgg tgatgaaata tctctaggag agcttatgca
    14941 gggtctaatg ctagtatctg gaaatgatgc tgctatagcc atagctaaac atattggtaa
    15001 gactgaaaag aattttgtaa atatgatgaa caagaaagca gaagaaatag gaatgattga
    15061 tacgtattat tttaatccaa atgggcttcc tatatatact gacccagaac ataaagaacc
    15121 tcctattgaa aatatgtcaa ctgctcacga tatagttaca cttggaaagt atatgtatga
    15181 ccattatgaa aatcaagtta caagaataac cactatgcaa gtatataatg atactaaaaa
    15241 ggattttaca cattataaca caaatcccct acttgtttca gtacctggtg ttgatggaat
    15301 aaagacaggc tatacagata atgctggata ttgccttgca ttttctatga tggtacctaa
    15361 agatgctaaa aacgaaagaa atcatagatt gataggtgtt gtacttggtg atggtaacaa
    15421 gaaaaataga atttcttctt ccgctacttt attgaaatat ggtaaagata atttccattc
    15481 taaaaagata gcacataagg gtgatattat agagactcct tgtgttgatg gtattgatga
    15541 ttttaagata acagttaagg ttgataaaga tttgtatggt gttgtttcag ataacgaaaa
    15601 tatcaatcct aaggtagtgt ttaaaaatat gaattatcct atccataagg gagatattgt
    15661 tggtgttgca aagtattata atgactctgg taaatttgtt ggaagtgttg atgtaaaaag
    15721 tgaaagtaat ataggatgta ttcctttgaa ggataagatt aagattaagg ttgctaagat
    15781 aaataaaaaa cttgagatta aaaattctgt ttgttttaaa gtatagtaaa gcatactatt
    15841 aaaagagtat attaaattta taaatactcc actttgtgga gtttttttgt tttttacaaa
    15901 aaattaaaat agtggcaaca attgaggatg tgagggagag ttgccactat tttgtatagg
    15961 gtattatatt atgtttttaa gctagtttta ctatcttcta tgtttatata ataactcttg
    16021 tgtgtgaatt taattgataa ttaatatgaa aattatgtga agttttgata ttaggttata
    16081 ctttgaactt tatctaacat tttaaatttt atatctctaa attatctaaa attactatat
    16141 caattaactt tacatgataa aaaggctgtg tataaattta tttttaaaaa ttttactcac
    16201 agccttaaat taaattttct atttaaagta tatataaatt ttattaaata atttgctttt
    16261 tatttcttat ttcataaatc ctagtattct tgataacatt aatgcaattg tagtaggtac
    16321 tttccctgct tcaaatgtag ctgttgctgt gtttaatgct gttactgcat catctatttc
    16381 tttttgtgtt gcatctgctt tatctaatat tgcttgtgct tcatctattg ctgttttata
    16441 tgt
//
LOCUS       DAMJYN010000081        16223 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.085, whole genome shotgun sequence.
ACCESSION   DAMJYN010000081 DAMJYN010000000
VERSION     DAMJYN010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16223)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16223)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16223
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.085"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            40..282
                     /locus_tag="PC466_002909"
     CDS             40..282
                     /locus_tag="PC466_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HDF2770273.1"
                     /translation="MQNSMKQEPCDFSHGRFRFKTSDNRVLIPVVIFLGSIVTALCDL
                     ISRVILSPVELPISTITSLLGAPIVVMLLVKRKDRA"
     gene            285..1481
                     /locus_tag="PC466_002910"
     CDS             285..1481
                     /locus_tag="PC466_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2770274.1"
                     /translation="MLKTNNLSVGYNNKVVISNINVEVKNGEILCLLGSNGAGKTTLL
                     RSLSKLISPIKGEIYLNGVNINCISRKALSKKMALVLTNRLLGDLMTVQDIVNIGRYP
                     YTGFFGSLSKKDLIMVDEALESVDALHLKKRYFDELSDGEKQKVLVARALVQEPEIII
                     LDEPTTHLDIKHRLELINILKKLSKEKSISVILSLHEIDIALKSCDKVALIKNNKVIA
                     YGQPEDVVDEDIINSLYELDDKNFNSLLGSVEISNKSKNEVFIIGGGGKATPIYRAFT
                     KKGIGLYSGIIHENDIDYEIGRTMGIKMFTENPFEPISDESFDLAIRNLNDSKIIIDT
                     GFSVGETNKRNIDIIKEALKLDKKVYSFRNRDESKKYYDSLDSKIEHIDKVSQIINSA
                     DINNLL"
     gene            complement(1601..2326)
                     /locus_tag="PC466_002911"
     CDS             complement(1601..2326)
                     /locus_tag="PC466_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HDF2770275.1"
                     /translation="MKTISKQELEKTLEKHYLWLKNNNAGEKADLKELRLENMDLRGY
                     CLSNIDFSWSDLINLNLEKADLENSIFNNSYLSDCSLKNSILKNADLSGANFRFCDLS
                     NSDIRGANLENSNLEHATLNGVISDESTPFFKLYCPETGAFIGYKKCFNFRMVQLLIP
                     SDAKRVSATSNACRCDKAKVLSITSIDGKESFKSARAYADENFIYRVGETIVAEDFNE
                     NRWKESTTGIHFFLTREEAIGYL"
     gene            2804..4903
                     /gene="nrdE"
                     /locus_tag="PC466_002912"
     CDS             2804..4903
                     /gene="nrdE"
                     /locus_tag="PC466_002912"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HDF2770276.1"
                     /translation="MNWIELNNQVIIKNEQGKYQLEKDKEALSSYIEEFIQPKLRKFN
                     NLEERLKYLIDEGYYLKEVINQYSIDVIKNIYDMIDKHKFEFQSYMSANKFYQNYALK
                     SNDGKEILETYNDKVLIVALTLGNGDKDLALNLADKIVKQEFQPATPTFLNAGRKRAG
                     EMVSCFLLSVEDSTEGISYAISSSNHLSKIGGGVALNLSKLRASGESIKDIEGAAGGV
                     VGVAKMLEQSFSYFNQMGARQGSGAVYLTVFHPDFELLMDTKKINADEKIRLATLSLG
                     AIIPDKFMELAEKNEVAYAFYPHTVYKKYGVSLDEIEMDEWYDKLVNDSDIRKKEINP
                     RQMLTKIAQMQQESGYPYVVYIDTANREHTLKDVGIIKMSNLCCEIFQYQTPSEIEGY
                     GGKNEWGQDISCNLGSLNIANVMDNKTIESTVETAIRALSFVADSTDIKPVPTVSNSN
                     SKSHSIGLGAMNLHGYLVRENILYTSDDAIDFSNVFFAMVRYYSIKASMKIAIERNQT
                     FEGFDKSEYVKGRNSKVLSKYYEQSYLPKSEKVRALFEGIYIPTKEDWTKLLDEVKEK
                     GIYNAYLMAVAPTQSISYVQNATSSIMPITEPVEVRTYGDSTTIYPMPFLTNDNMLYY
                     QSAYRMDMRKVIDLVATVQNHVDQGISTTLFVTDEKTTRDIARHYIYAYKKGLKSLYY
                     TRTKMTRDTHECLVCSV"
     gene            4916..5887
                     /gene="nrdF"
                     /locus_tag="PC466_002913"
     CDS             4916..5887
                     /gene="nrdF"
                     /locus_tag="PC466_002913"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HDF2770277.1"
                     /translation="MTFNLHKIHNAVNWNREEDGFTQAFWEQNVKQFWLPEEISVSKD
                     IKVWNELSNKEKELYKKVLGGLTLLDTKQGNNGIPSMMSLTENLQRKAVLSFMGTMEE
                     IHAKSYSSIFMTLLSNLEIDELFEWIETEPTLQRKADLVLAQYENTTNQEGLYLSMVT
                     SVFLESFLFYSGFFYPLYLSGQGKMVASGEIISLILRDESLHGKYIGLLAQEIYDSFD
                     KMDKKMLEEKMYSILYSLMENEIEYTNVIYRESGLEKEVVNFLKYNANRALENLGFEK
                     LYTVDAINPIVLNGLSTETKTHDFFSTKGNGYQKGVYEELEDEDFII"
     gene            5963..6589
                     /locus_tag="PC466_002914"
     CDS             5963..6589
                     /locus_tag="PC466_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HDF2770278.1"
                     /translation="MKYEWRKRDKELYLPKKNPVIIEIPEQKFIMLKGSGDPNSKEFI
                     EAIGVLYSLAYAIKTMPKKGIVPEGYFDYTVFPLEGIWDKGEKSKGLDVLIKEDLIYT
                     IMIRQPDFVTQDLLDKATDIVKKKKPHNLLEKVRFGSINEGLCVQMLHIGSYDNEPES
                     FDIMNEFCKKNKLIRKSYTHREIYISDARKVSPESLKTVLRFEVEREV"
     gene            6984..7613
                     /locus_tag="PC466_002915"
     CDS             6984..7613
                     /locus_tag="PC466_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770279.1"
                     /translation="MNKYLLINPVAERMYGEKFHLIKANLIKKGYIIAECEPQLEYVK
                     KQYKEYTKKTENTMLDCRCPESISLLKRNNLINNFEVPMIEPILVRTCRVLYDKYIKS
                     KDDMLVVTCPCTQLRDFASEKFKDKGNAMFYTWKEFAEQEGVKSLGKIDESPIPLGYF
                     KDTFEKVLEVSSEDEILSEIQKIRNGFEDKYDIVEMFYCKDGCNNGDGL"
     gene            7614..8396
                     /locus_tag="PC466_002916"
     CDS             7614..8396
                     /locus_tag="PC466_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2770280.1"
                     /translation="MVNKFNNKFLRLVKSVLIFFIILLLWKITNYLGIWSDYILPSPE
                     KVYSTFLNMISDGSIFINVYASMKRVLIGFAINTAIGVPLGIFFGIYSGVYEYFKSLI
                     NFLRNTPPLALIPMLILWFGIGEESKIIIIVLASFFPIFTSTLKGIKNCDSKLIEVGR
                     VFEFSKLQIIFKIIIPNAILDIAVGLKLALGYSFRAIIGAELVAASSGLGYLISDGKE
                     MSRTDVVIVGIIVIGLLGIITDYIFSIIVKKVSKGKMVEAYE"
     gene            8389..9267
                     /locus_tag="PC466_002917"
     CDS             8389..9267
                     /locus_tag="PC466_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2770281.1"
                     /translation="MNNLVCDSGYIIRNLYKSYKVDNEEHVVLSDISLNIDRNHITVI
                     LGESGCGKTTLLRAIASLEGINSGEIRFINDNKEYRPNVGFVFQESRLMPWLNVSENI
                     AFHNQRKNTILNKVLRKFKHNKRIIGKIINDNFRSLETNDNLNKSNKYNRKSNIDVEK
                     YLKMMNLQKFKNSYPNELSGGMAQRVSIARALSFNPDMLLMDEPFSALDYFTRIDMQN
                     EVIKIHKSTNKGVIFVTHDIDEALKIGKKIVVFTDERKIKEFNIEDGYNRDLTSEYYI
                     KLKKDILMTMKSNKDI"
     gene            9300..10259
                     /locus_tag="PC466_002918"
     CDS             9300..10259
                     /locus_tag="PC466_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NrtA/SsuA/CpmA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HDF2770282.1"
                     /translation="MKLKKLLIGITILTLATASLAGCAKKNNGEKLSEINLTYVKSPL
                     NVPSIIQKQDDLFGKEFKKDNIKVNFHEITTGPEQTQALAAGEIDFLHALGGTSALIA
                     ASNGVELKILNTYSRSPKGFMILTNNNSIKSAADLVGKKVAGPKGTILHQVLISALDK
                     EGLSMDDVEFVNMGIPEASAALSDGSVDVALIAGPAALKAMKSGSKLVANGEGLVDGI
                     IVTAVSTDFAEKHPEIVERFMKVEKETLEYVNNNFDEAMEKVAKEVDLSLEETKELYA
                     WYDFSLDITDKDISSLEDTQDFLIKNKLQEKKVNIKELIYNAK"
     gene            10573..11265
                     /locus_tag="PC466_002919"
     CDS             10573..11265
                     /locus_tag="PC466_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011987369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2770283.1"
                     /translation="MSYKVYIVEDDISISTLLKDYIEKYGFEVIVEENFDDIMITFES
                     FKPHLVLLDVNLPKFDGFYWCRCIRQQSNLPIIFISARDGNVDQIRALESGADDYITK
                     PFYYDVVMAKIKSHIRRVYGEYSPKIDERIVELDGLKFYPERLELELNGENLIITKKE
                     GILIECLIKRYPKVVSRDYLLEKIWDDIEFVEENTLNVNVSRIRKRFEELGIDNAVQT
                     VRGLGYKLNKNW"
     gene            11275..12279
                     /locus_tag="PC466_002920"
     CDS             11275..12279
                     /locus_tag="PC466_002920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2770284.1"
                     /translation="MKLFLKDYKGYIFIYYIGIVMTIIYCNLMKFISFGESLYILLFS
                     SFILLCFLIYKYYKNREVYNLFEKGIHSLEESFLYLGSSFLGRNISVILKQQHKLYQS
                     MIQEHKKIHSEHLTFINQWIHQMKTPISVISLQLQDYEGEEVTENIRKEIDRLNKGLD
                     MAMHFARADNFQKDFIVEKAKLNEIVSSIVNEEKRLFIKSGMIPKIQVDKFTYVYTDV
                     KWMKFIIGQLITNGVKYSKDYSNYLTIKSEENNKYVILSIIDEGIGIVSKDLKRVFDP
                     FFTGENGRKFGESTGMGLYLVKKVCDDLGHKVSIKSEVGKGTEVSIYFNKDVNSLIKM
                     "
     gene            12527..13378
                     /locus_tag="PC466_002921"
     CDS             12527..13378
                     /locus_tag="PC466_002921"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HDF2770285.1"
                     /translation="MSLDVIFILKSVIIAIVEGFTEFIPVSSTGHMILVGNLIDFKGQ
                     FAEMFEVVIQLGAILAVVVLYWKKIKDSVIEFFKFIFTGGKEGKIGFRFGMNVIIGCI
                     PFAIIGVLFYDNIKSLFNLQSVIIGFIVGGILLLVVETLFRKKNHSTDNIDKITPIQA
                     LKVGTLQVLSAWPGMSRSASTIMGGWIAGLNSPTAAEFSFFLAVPAMVASSGKDLFEF
                     DYSIMTPTLWIALVVGFIVAFIVSIIVMEKFVNFLKKKPMRVFAVYRIIMGVVLAVLA
                     FTNIISV"
     gene            13482..14228
                     /locus_tag="PC466_002922"
     CDS             13482..14228
                     /locus_tag="PC466_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001637630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2770286.1"
                     /translation="MKILTVNNLSKVYGKKIIFNALNDINFSIEDGEFVGIMGPSGSG
                     KTTLLNMISTIDKPTTGTMELKGKNPLLLRGEELALFRRRELGFVFQDFNLLDTLTIG
                     ENIVLPLTLDKVSVKEQDERLNEVSTILGIKDLLGKRTFEVSGGQAQRTAIARALINN
                     PSILLADEPTGNLDSKSSKVVMELFQKINKENKVTTMMVTHDPLAASYCSRILFIKDG
                     SIYNEIYKGSSREQFYQEIMDVLTLLGGDN"
     gene            14228..16144
                     /locus_tag="PC466_002923"
     CDS             14228..16144
                     /locus_tag="PC466_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2770287.1"
                     /translation="MNIKQFAINNISRNIKAYLGYLASIVISSSLLFSFIMFTSHPDL
                     DVSQFPDYLKEGLKMSKIIAYLFLFFFVFYSVSVFLKSRYKEFGILYITGISKRQVMK
                     LIFIENMIINIVSSVIGIIIGLIFAKIFLVVMSTFLELSPLKFYIPFNAILSTLIYFM
                     ILAVLTSIFTYFIVKENQVLKLLKGTKTPKPEPKTSLMLAILSICLFIIAYYNAITST
                     DQYTTYLRLVPVTSLTIVATYLFFSQFSVFFMKKLKLNKRFYRKNTNMLWISNLIYKV
                     KDNARIFFLITITSAVAFTAIGTVYSFWKDVERQINLIYPNTIYYSTMTLHNDPKKPD
                     SKEKDKERMMFIENNLKKENVDYTRTNGEFKTVFPKKSDFNVRIMKESKYLEITETIG
                     VKPISFEDNECISLLSSSLPGNNNVKENIIVGNRGLKVAKQVEECVMPAYYKNMYVVK
                     DNFYDSIESKFIVDRFTAFEVEDSSKTIEICREFENKFNNESGMQPYLFFSKELMIGT
                     GKLIYSTFIFLAIFIGLIFFVTTSSFLYNKFYMDCQVDKKKYEQLNKLGMTYNEIKKA
                     STIEIGIVFLFPYVVAVIHSIFALTALKNSFDIEVASSAVLVMGSLFLVQIVYFLIVR
                     NNYLKEIRLNLVNF"
BASE COUNT         6348 a         1621 c         2839 g         5415 t
ORIGIN      
        1 ggggatggcc tgtggagaat tagtaagaca tattttagta tgcaaaattc tatgaagcag
       61 gaaccctgtg actttagtca tgggaggttc agatttaaaa catcagataa tagagttttg
      121 ataccagtag taatattttt aggcagtata gttacagctc tttgtgattt aatatcaaga
      181 gtaattttat caccagtaga attaccaata agcacgataa catctttatt aggagctcca
      241 attgtagtaa tgttattggt gaaaaggaag gatagggctt agacatgttg aaaactaata
      301 atttaagtgt aggatacaat aacaaggtag ttataagtaa tataaatgta gaagtaaaaa
      361 atggagaaat actatgtctt ttgggaagta atggagctgg aaaaactacc ctattaaggt
      421 ccttatctaa acttatatca ccaataaaag gtgaaatata tttgaatggt gtaaacataa
      481 attgtatatc aagaaaagca ttatcaaaaa aaatggcttt agtacttaca aatagattat
      541 taggtgattt aatgactgta caagatatag tcaatatagg aaggtatcca tatacaggat
      601 tttttgggag tctatctaag aaagatttaa taatggtaga tgaagcattg gagtctgtag
      661 atgccttaca tttaaagaaa agatattttg atgaactaag tgatggagaa aaacaaaagg
      721 tgttggttgc aagagctctt gttcaagaac cagaaataat tatattagat gagcctacaa
      781 ctcacttgga tataaaacat agattggagc tcataaacat actgaaaaaa ttaagtaaag
      841 aaaagtcaat atcagtaata ctttcattgc atgaaataga catagcatta aaaagttgtg
      901 ataaagttgc tcttataaaa aataataaag tcatagctta tggtcagcct gaagatgtag
      961 tagatgagga tattataaat tcgctttatg aattggatga taaaaacttt aatagtcttt
     1021 taggttcagt agaaattagt aataaatcta aaaatgaagt ttttataatt ggtggtgggg
     1081 gtaaagcaac accaatttat agagctttta ctaaaaaagg tataggtctg tattctggaa
     1141 taatacatga aaatgatatt gattatgaaa ttggtagaac tatggggata aagatgttta
     1201 cagaaaatcc atttgagccg ataagtgatg agagtttcga tttggctatt agaaatttaa
     1261 atgattccaa gattataata gatacaggat ttagtgtagg agagacaaat aagaggaata
     1321 tagatattat aaaagaggct ttaaaactgg ataaaaaagt ttattctttt agaaatagag
     1381 atgagagtaa gaagtattat gacagtttgg atagtaagat agaacatata gataaagttt
     1441 ctcaaataat caatagtgca gatataaata atttattata atttatgaaa taaaatgtac
     1501 ttatgtgcta tagaaaaaag agtatagatt ataatttttt tgaaattaca atctatactc
     1561 ttttgttatt ttgtttatat atttataaaa ctttagcatt ttatagataa ccaatagctt
     1621 cctctctagt taaaaaaaag tgaatccctg tagtcgattc tttccatcta ttttcattaa
     1681 aatcttcagc tacaatcgtt tctcctactc tatatataaa attttcatca gcatatgcac
     1741 gagcactttt aaaagattct ttaccatcta tactagtaat tgacagtact tttgccttat
     1801 cacatctaca agcatttgat gtagcagaca ctctttttgc gtcgctgggt attaataatt
     1861 gtaccattct gaaattaaaa cattttttat agcctataaa tgctcctgtt tcaggacaat
     1921 acaatttaaa aaaaggggta ctttcatctg atattactcc atttaaagta gcatgttcta
     1981 aattggaatt ttctaaatta gctcctctaa tatctgagtt agataagtca caaaatctaa
     2041 aatttgcacc acttaagtct gcatttttta atatagaatt ttttaatgaa caatccgaaa
     2101 gataagaatt attaaaaata gagttttcta aatctgcttt ttctaaattt aaattgataa
     2161 ggtcagacca cgaaaagtca atattactta agcagtatcc tcttaagtcc atattttcta
     2221 atcttaattc ttttaaatct gccttttctc cagcattatt gtttttaagc cataaataat
     2281 gtttctcaag tgttttttct aattcttgtt tagaaatagt tttcattaaa atcaccttca
     2341 taaatttatt tttatatatg tagtagcaaa atagtcatat atttaattat ataacaataa
     2401 ataaaaaact tctaaataat atataaaata tcatcttgaa agtacttttt tcaatatatc
     2461 agaatatatt tttaagctat ttagagataa tttaaatttt taaacaggac ataataagct
     2521 tgtatttttt tatatttgag ttgataaaaa tttctttaaa taaaaataat gtcaattata
     2581 aagtaataaa agtttagata taaaaaaatt tgtgtatata ctatatgtag tatataatag
     2641 ataaagcact gactatatgt agtgcttttg tttttgaaaa atacttattg catttctata
     2701 attatagatt aattttggga tttcaactga taagtaccaa aagaaataat aagcaaatta
     2761 agtgaaatta tggcacaaga ttatgttaaa aggacggtaa ataatgaatt ggatagagct
     2821 taacaatcaa gtgataatta aaaatgaaca aggtaagtac caattggaaa aggataagga
     2881 agccttaagt agttacatag aagaatttat acaaccaaag ttgagaaaat ttaataacct
     2941 agaagaaaga ttgaagtatt taatagatga aggttattat ttaaaagaag taataaatca
     3001 gtatagcata gatgttatta aaaatatata tgatatgatt gataaacata agtttgaatt
     3061 tcaatcatat atgagtgcaa ataagtttta tcaaaattat gcattaaaga gcaatgatgg
     3121 aaaggaaata ttagaaacat ataatgataa agtgttaatt gtagctttga cactaggaaa
     3181 tggcgataaa gatttagctt taaacttggc agataaaata gtaaaacaag aatttcaacc
     3241 agctacacct acttttttaa atgctggaag aaagagggct ggagaaatgg tatcatgttt
     3301 tttactatct gtagaagata gtacagaagg tatatcatat gctatatctt catcaaatca
     3361 cttatcaaag attggtggag gagttgcact aaatttatct aaacttagag catctggcga
     3421 atctatcaaa gatatagaag gtgcagctgg aggtgttgtt ggagtagcta aaatgttaga
     3481 acaatcattt agttacttta atcaaatggg agctagacaa ggttctggtg cggtgtacct
     3541 tactgtattc catcctgatt ttgaattgtt gatggatact aaaaagataa atgcagatga
     3601 aaaaataaga cttgctacat tatcattagg agctataata ccagataaat ttatggagtt
     3661 ggcagaaaaa aatgaagtag catatgcatt ttatcctcat actgtgtata agaaatatgg
     3721 agtttctctt gatgagatag aaatggatga gtggtatgat aaattggtta atgatagtga
     3781 tataagaaaa aaagaaataa atcctaggca gatgttgaca aaaatagcac aaatgcaaca
     3841 agaaagtgga tatccatatg tagtgtacat agatacagct aatagagaac atacattaaa
     3901 agatgttgga attattaaaa tgtctaactt atgttgtgag atatttcaat atcaaacacc
     3961 ttcagaaata gaggggtatg gaggaaaaaa tgaatgggga caagatataa gttgtaacct
     4021 aggttcttta aacatagcca atgtaatgga taataaaact atagaaagta cagttgaaac
     4081 agcaataaga gcactgtcat ttgtagcaga tagcacagat ataaaaccag tgccaacggt
     4141 aagcaatagt aacagcaagt ctcattctat aggattagga gctatgaatt tacatggata
     4201 cttagtaaga gaaaatattt tatatacttc agatgatgct atagattttt ctaatgtatt
     4261 ttttgcaatg gttagatact attcaattaa agcttctatg aaaatagcca tagaaagaaa
     4321 tcaaactttt gaaggatttg ataaatcaga atatgttaag ggaagaaata gcaaggtttt
     4381 atcaaaatac tatgaacaat cttatctacc taagtcagaa aaggtaagag cattatttga
     4441 agggatttat ataccaacaa aagaagattg gacaaaatta ttggatgaag taaaagaaaa
     4501 agggatatat aatgcatatt taatggcagt agcaccaact caaagcatta gttatgttca
     4561 aaatgctaca tcaagtataa tgccaattac tgagccagta gaagtaagaa catatggaga
     4621 ctctactaca atatatccaa tgccattttt aacaaatgat aatatgttgt attatcaatc
     4681 agcatacagg atggatatga gaaaggtcat agatttagtg gcaacagttc aaaaccatgt
     4741 tgaccaaggt atatcaacaa cactgtttgt tacagatgaa aagacaacta gagatatagc
     4801 tagacattac atatatgcct ataaaaaagg tttgaaaagt ttatattaca caagaacaaa
     4861 gatgacaaga gatactcatg agtgtctagt gtgttcagta tagggagaga aatatatgac
     4921 atttaattta cataaaatac ataatgcagt taactggaat agagaagaag atggatttac
     4981 acaagctttt tgggaacaaa atgtaaaaca attttggctt cctgaagaaa tatctgtttc
     5041 taaagacata aaggtatgga atgaactaag taataaagaa aaggaattat ataaaaaagt
     5101 attgggtggt ttaacattac tggatacaaa acaggggaat aatggaatac catctatgat
     5161 gagtttaaca gaaaacctac aaagaaaagc tgtcttgtct tttatgggga ctatggaaga
     5221 aatacatgca aaaagttatt cttctatatt tatgactcta ctttctaatt tagaaataga
     5281 tgaattattt gaatggatag aaacagaacc aacattacaa agaaaggctg atttagtttt
     5341 agctcaatac gaaaatacta caaatcaaga gggattatac ctatcaatgg ttacaagtgt
     5401 atttttagag agtttcttgt tttattcagg attcttttat ccattgtatc tatctggtca
     5461 aggaaagatg gtagctagtg gagaaataat atcgcttatt cttagagatg agtctttaca
     5521 tggtaagtat ataggattgc tagcacaaga aatatacgat tcatttgata aaatggataa
     5581 gaagatgtta gaagagaaga tgtattctat actttatagc cttatggaga atgagataga
     5641 gtatacaaat gttatataca gagaaagtgg gcttgaaaaa gaggttgtga actttttaaa
     5701 atacaatgcg aatagagctt tagaaaatct agggtttgag aagctatata ctgtagatgc
     5761 tataaatcca attgtattaa atggtcttag cactgaaacc aaaacacatg atttcttttc
     5821 aactaagggt aatggatacc aaaaaggagt gtatgaggaa ttagaggatg aagattttat
     5881 aatataattt ataattatga cacactgttg tcacttttag cgtgataata tcaatgtata
     5941 aaatatatat ggaggtattt ttatgaaata tgaatggaga aaaagagata aagagttata
     6001 tttacctaaa aagaatcctg taataattga aataccagaa cagaaattta tcatgttaaa
     6061 agggagtgga gacccaaatt ctaaagaatt tattgaagca ataggagtac tttattcttt
     6121 ggcatatgca ataaaaacca tgcctaaaaa aggaattgta ccagaagggt attttgacta
     6181 tacggttttt cctttagaag gtatatggga taagggagaa aaaagtaaag gcttagatgt
     6241 acttattaaa gaagatttaa tttacactat aatgatacgt cagccagatt ttgttacaca
     6301 agacctgttg gataaagcta ctgatatagt aaagaagaag aaacctcata atcttcttga
     6361 aaaagttagg tttgggtcta ttaatgaagg gctatgtgtt caaatgcttc atataggttc
     6421 atatgataat gaaccagaaa gttttgacat tatgaacgaa ttttgcaaaa aaaataaact
     6481 tataagaaaa tcttacacac atcgtgaaat ttatataagt gatgctagaa aagtatcgcc
     6541 tgaatcattg aagacggttt tacgttttga agtagaaagg gaagtataaa tattttgaat
     6601 aatttataag agttataaaa agtgaagtct gttgagactt cattttttga tgcaatttta
     6661 aaattaaatt tgatgtttca taatatttta aaaactttct acttttatta gtgtgaataa
     6721 ctgttgctat taaataataa tactaattat ataagtatta ttatataata tttatagatt
     6781 attatataaa tagattatta gtaagatgta tgcattatta attaaaataa attacatata
     6841 ctatttaata tttcatttaa aatattaaaa aatgtagata aaaattgttt tattaaggaa
     6901 aaattaatat attgacaaaa tttaagtgct catttaaact attaattgat aataatattc
     6961 aatattaaat aataggaggc gttatgaata aatatcttct aataaatcca gtggcagaaa
     7021 gaatgtatgg agaaaagttt caccttatta aagcaaattt gataaaaaag gggtacataa
     7081 tagcagaatg tgaaccacag ttagaatatg taaaaaagca gtacaaagag tatacaaaaa
     7141 agactgaaaa tacaatgttg gattgtagat gtccagaaag tataagtctt ttaaaaagaa
     7201 ataatttgat aaataatttt gaagtaccta tgatagaacc aatattagta aggacttgta
     7261 gggttttata cgataaatat ataaaaagta aagatgatat gttggtagta acctgtccat
     7321 gtacacaatt aagagacttt gcaagtgaaa agtttaagga taagggtaat gctatgtttt
     7381 atacatggaa agagtttgct gaacaagaag gtgtaaaatc acttggaaaa atagatgaat
     7441 caccaattcc attaggatat ttcaaagata cttttgaaaa agttcttgaa gtatcaagtg
     7501 aagacgaaat attaagtgaa atacaaaaaa taagaaatgg ctttgaagat aagtatgaca
     7561 tagtagaaat gttttattgt aaagatggtt gtaataatgg agatggtttg taaatggtca
     7621 ataaatttaa taataagttt ttaaggctag taaagagtgt tctgatattt tttataattc
     7681 ttttattatg gaaaattaca aattatcttg gtatttggag tgattatata ttaccatcac
     7741 ccgaaaaggt atatagtaca tttttaaata tgataagtga tggttcaata tttattaatg
     7801 tatatgcaag tatgaaaaga gttttgatag gttttgcaat aaatactgct ataggtgtgc
     7861 ctttagggat attctttgga atttatagtg gagtatacga atactttaaa tctctaataa
     7921 attttttaag gaatacacct ccccttgctt taataccaat gcttatatta tggtttggta
     7981 taggagagga atcaaaaatt ataattatag ttttagcatc ctttttccca atctttacaa
     8041 gcacattgaa agggattaaa aattgtgact caaaactgat tgaagtgggt agagtatttg
     8101 agttttcaaa gcttcagata atatttaaaa taataatacc aaatgccatt cttgatattg
     8161 ctgttgggtt aaagttagct cttggatata gctttagagc aattattggg gcagaacttg
     8221 tagcagcttc atctggtctt ggatacttga tatctgatgg aaaagaaatg tctagaacag
     8281 atgttgttat tgtaggtata atcgtaattg gacttttagg aataattaca gattacatat
     8341 tttcgattat tgtgaagaag gtaagtaagg gaaagatggt ggaagcatat gaataattta
     8401 gtatgtgact ctggatatat aattagaaat ttatataaaa gttataaagt tgacaatgaa
     8461 gaacatgtag ttcttagtga tatctcttta aacatagata gaaaccatat aacagtaatt
     8521 ttaggtgaaa gtggttgtgg aaagactacc ttgcttagag caattgcatc acttgaaggt
     8581 ataaatagtg gtgagattag gtttattaat gataataaag agtatagacc taatgttggt
     8641 tttgtttttc aggagagcag attaatgcct tggttaaacg taagtgaaaa tatagctttt
     8701 cataatcaaa gaaaaaatac tattttaaac aaggtgctta gaaaatttaa acacaataaa
     8761 agaattattg gtaaaattat aaatgataat tttagaagct tagaaacaaa tgataatttg
     8821 aacaaatcaa ataaatataa taggaaaagt aatattgatg tagaaaaata tcttaagatg
     8881 atgaacttgc agaaatttaa aaactcttat ccaaatgaat tgtcaggagg tatggcacag
     8941 agagtaagca tagctagagc tctttctttc aatccagata tgttgcttat ggacgagcct
     9001 ttttcggcat tagattattt tacaaggatt gatatgcaaa atgaagttat aaaaatacat
     9061 aagtcaacta ataaaggcgt aatatttgta actcatgata ttgatgaagc gttaaagata
     9121 ggcaaaaaaa tagttgtttt cacagacgaa agaaaaataa aagaatttaa tatagaagat
     9181 ggttataata gagatttaac ttcagagtac tatattaaat taaaaaaaga tattttaatg
     9241 acaatgaaat caaataaaga catttaaaga aattaataat attttaagga gtagagtaaa
     9301 tgaaattaaa aaagctattg ataggtataa cgatattaac acttgcaaca gcatctttag
     9361 ctggatgtgc taaaaaaaat aatggagaaa aactttcaga aataaattta acttatgtaa
     9421 aatcaccatt aaatgttcct tctataattc agaaacagga tgatttattt ggaaaggaat
     9481 ttaaaaagga taatataaaa gttaactttc acgaaattac tacaggtcca gagcaaacac
     9541 aggctttagc tgctggagaa atagacttct tacatgcact aggtggtacg tcagctttaa
     9601 tagctgcatc taatggagta gagttaaaga tattaaacac ttatagcagg tcaccaaaag
     9661 gatttatgat tttgactaat aataattcaa taaaatcagc agcagattta gtaggtaaga
     9721 aggtggcagg tccaaaaggg actatattac atcaggtatt gatttcagca cttgataaag
     9781 aaggattaag tatggatgat gtggaatttg ttaatatggg tattccagaa gcatcagcag
     9841 ctctttctga tggtagcgta gatgttgcat tgattgctgg tccagcagct cttaaagcta
     9901 tgaagtcagg tagtaaactt gtagcaaatg gtgaaggttt agtagatggt ataatagtaa
     9961 ctgctgttag cacagacttt gcagagaaac acccagaaat agttgaaaga tttatgaagg
    10021 ttgaaaagga aactttagaa tatgtaaata ataattttga tgaagctatg gaaaaagtag
    10081 ctaaagaagt tgatttaagt cttgaagaaa ctaaagaatt atatgcttgg tatgatttta
    10141 gtttagatat aacagataaa gatatatctt cgcttgaaga tacacaagac ttcttaataa
    10201 aaaataagtt acaagagaaa aaagtgaata taaaagaatt aatctataat gctaagtaga
    10261 aactatgcta aaataatact aagtaagaaa tataataaaa gtttaagtta ccttattaag
    10321 gtaacttttt ctattttgaa ttagtaattt caatttattt tagaatgatt agttgataat
    10381 aatgattaat taatcataaa aagatacttt tttatagagt tttattaaga tgtctaataa
    10441 tatggttata cttatgaagt cagtaattgt gaagttaata atatgattaa atttatatat
    10501 tgtaaaaaga ttataatata ttaaaattgg actgttatat gatgagtaaa taggtatatt
    10561 aggaggaatt atatgagtta taaagtatat attgtggaag atgatatatc aataagtaca
    10621 ttacttaaag attatattga gaaatatgga tttgaagtga ttgttgaaga gaactttgat
    10681 gatataatga ttacatttga aagttttaag ccacacttag ttctattaga tgtaaattta
    10741 cctaaatttg atggtttcta ctggtgtaga tgtattagac aacagtcgaa tttacctata
    10801 atttttatat cagctagaga tggcaatgta gaccaaatta gagctttaga aagtggagca
    10861 gatgattata taacaaaacc tttttactat gatgtagtaa tggcaaaaat aaagagtcat
    10921 ataagaaggg tatatggtga atattcacct aaaatagacg aaagaatagt ggagctagat
    10981 ggattaaagt tttatccaga aaggttagaa ctagaattaa atggtgaaaa tctaattata
    11041 actaaaaaag aaggtatact gattgaatgt cttatcaaga gatacccaaa agtagtaagt
    11101 agagattatc ttttagaaaa gatatgggat gatattgagt ttgtagaaga aaatacttta
    11161 aatgtaaatg ttagcaggat aaggaaaaga tttgaggaat taggtataga taatgctgtt
    11221 cagactgtcc gagggttagg atataaatta aataagaatt ggtaaggaga aagtatgaag
    11281 ttatttttaa aagattataa aggttatatt tttatatatt atataggcat agttatgaca
    11341 attatttact gtaatcttat gaagtttatt agttttggag agagtttata tattctttta
    11401 tttagttctt ttatattgtt atgtttttta atatataagt attataaaaa tagagaagta
    11461 tataatctgt ttgaaaaagg aatacattct ttggaggagt catttttgta tttaggaagc
    11521 tcattcttgg ggagaaatat atcagttatt ttaaaacaac aacataaatt gtatcaatca
    11581 atgatacaag agcataaaaa gatacatagt gaacatttaa ctttcatcaa ccaatggatt
    11641 catcagatga aaacaccaat atcagttata agccttcagc ttcaagatta tgagggagaa
    11701 gaagtaactg aaaatataag aaaagaaata gatagattaa ataaagggtt agatatggct
    11761 atgcattttg caagggcaga taattttcag aaagacttta tagttgaaaa agccaaatta
    11821 aatgaaattg tatctagtat tgtaaatgaa gaaaaaaggt tatttataaa aagtggaatg
    11881 attcctaaga ttcaagtaga caaatttact tatgtttata cagatgtaaa atggatgaaa
    11941 tttataatag gtcaattaat tacaaatgga gtgaaatatt ctaaagatta tagtaactac
    12001 ctaactataa aatctgaaga aaataataaa tatgtaattt taagtataat agatgaagga
    12061 attggaattg tttctaaaga tttaaaaagg gtatttgacc cattttttac aggagaaaat
    12121 ggtcgtaagt ttggagaatc tacaggtatg ggtctttatc tagtaaaaaa ggtatgtgat
    12181 gatttaggtc ataaagtaag tataaaatca gaagtaggaa aaggtacaga agtttcaatc
    12241 tactttaata aagatgtaaa tagtttgata aagatgtaaa ttatctgtta caatagggtt
    12301 tttagttaat tgtacttttt tattatacaa tttattaaat gaaatattca tagttaaata
    12361 atcaaaattt aagagagttt atttgcaaac cttacataga tgtaaggttt gtgtaatgtt
    12421 tgcagatagt taaattttct aatctaaatt acaattaata taagaaataa catgagagaa
    12481 ataacataaa aaaagaaatt ttgtaaaaaa ggaaggatgt ttattgatga gtttagatgt
    12541 tatttttata ttgaaatcag tcataatagc tatagtagag gggtttacag aatttattcc
    12601 agtttcatct acaggtcata tgattttggt tggtaattta atagatttta aggggcaatt
    12661 tgctgaaatg tttgaggttg taatacaact tggggctata ttagcagtag tagtacttta
    12721 ttggaaaaag ataaaagata gcgttataga attttttaaa tttatattta ctggcggaaa
    12781 agaaggaaag attggtttta gatttggaat gaatgtaatt ataggttgta taccatttgc
    12841 gattatagga gttctatttt atgataatat aaaatcattg tttaatttac aatctgtaat
    12901 tataggattt atagtgggtg ggattttatt attagtagta gaaactttgt ttagaaaaaa
    12961 gaatcattca acagataata tagataaaat tactccaata caagctttaa aggttgggac
    13021 attacaagtt ttgtctgcat ggccaggtat gtcaaggagt gcatctacta ttatgggtgg
    13081 atggatagca ggacttaatt ctcctacagc agctgagttt tctttctttt tagcagtacc
    13141 agctatggtg gcttcttcag gaaaagattt atttgaattt gattattcaa taatgacacc
    13201 aacattgtgg attgctttgg tagttgggtt tatagtagct tttattgtat caataatagt
    13261 tatggaaaaa ttcgtgaatt ttttaaagaa aaaaccaatg agagtgtttg ctgtatacag
    13321 aataatcatg ggtgtagtac ttgcagtatt agcttttact aacataatta gtgtatagaa
    13381 aaaatagatt tattatctat aaaaattaaa ctaagataaa ttataattaa caattatata
    13441 tatgttattt caaaaattaa attaggaagg atagttaaat aatgaaaatt ttaactgtaa
    13501 ataatttaag taaagtatat ggtaaaaaaa taattttcaa cgcattaaat gacataaatt
    13561 ttagtataga agatggagaa tttgtaggaa ttatgggtcc atctggtagt ggaaaaacta
    13621 ctcttttaaa tatgatttct actattgaca agccaactac aggaactatg gaattaaagg
    13681 gaaagaatcc tttattgtta agaggtgagg aacttgcatt atttagaaga agagagttag
    13741 gttttgtatt tcaggatttt aatttattgg atacattaac tataggagaa aatatagtat
    13801 tgccattgac attagataag gtcagtgtaa aagagcaaga tgagagattg aatgaagtat
    13861 ctacaatatt aggtataaaa gatttattag gaaaaagaac ttttgaagta tcaggtggtc
    13921 aagctcagag gactgctatt gctagagcat tgattaacaa tccatcaata cttttagcag
    13981 atgaaccaac aggtaattta gattcaaagt catcaaaggt tgtaatggag ctatttcaaa
    14041 agataaataa agaaaataaa gttactacta tgatggtaac tcatgaccca ttagcagcga
    14101 gctactgtag tagaatctta ttcataaaag atgggtctat atataatgaa atatataagg
    14161 gtagtagtag agagcagttt tatcaagaga taatggatgt acttacatta ttgggaggcg
    14221 ataactaatg aatataaaac agtttgctat taacaatatt tcaagaaata ttaaagcgta
    14281 tttaggatac ttagcaagta ttgttatatc atcttcactg ctattttctt ttattatgtt
    14341 tacaagtcat ccagatttag atgtatctca atttcctgat tatttaaaag aaggtctcaa
    14401 gatgagtaag ataattgcat atctattctt attcttcttt gtgttttatt cagttagtgt
    14461 gtttcttaaa agtagatata aagaatttgg aatactttat attacaggta tatcaaaacg
    14521 ccaagtaatg aaattaatct ttatagaaaa tatgataata aatatagtat cttctgtaat
    14581 tggaataata ataggcttaa tctttgcaaa gatattttta gtggttatgt ctactttttt
    14641 agaattatcg ccattaaaat tctatatacc atttaatgcg atattgtcta ctttaatcta
    14701 ttttatgatt ttagctgtat taacatcaat atttacttat tttatagtta aagaaaatca
    14761 ggtgttgaag ttacttaaag gtacaaaaac tccaaaacca gagcctaaaa catcactaat
    14821 gcttgctata ttaagtattt gtttgtttat aatagcgtat tataatgcta ttacctcaac
    14881 cgaccaatat acaacatatc tgcgcttagt tccagttaca tcccttacta tagtagcaac
    14941 ttacttgttc ttttctcaat ttagtgtatt ttttatgaag aagctaaaac taaacaagag
    15001 attttataga aaaaatacaa atatgctttg gatttcgaac ttgatttata aggtaaagga
    15061 taatgctaga atatttttct tgataactat aacttctgca gtagcattta ctgctatagg
    15121 tacagtttat tccttttgga aagatgtaga gcgtcaaatt aatttaatat atcctaacac
    15181 aatatattat tcaacaatga cattgcataa tgaccctaaa aagcctgata gcaaagaaaa
    15241 agacaaggaa agaatgatgt ttatagaaaa taatctaaaa aaagagaatg tagactatac
    15301 aaggactaat ggtgaattta aaactgtatt tcccaagaaa agtgatttta atgtcagaat
    15361 tatgaaagaa tctaagtact tagaaattac agaaactata ggggttaagc ctataagttt
    15421 tgaagataat gaatgcatat cattattatc atcaagttta ccaggaaata ataacgtcaa
    15481 agaaaatatt attgtaggga atagaggttt aaaggtggca aaacaagtgg aagaatgtgt
    15541 tatgccagca tattacaaaa atatgtatgt ggtaaaggat aatttttatg atagtataga
    15601 atcaaaattt atagtggata gatttactgc atttgaagta gaggattcaa gtaaaactat
    15661 agagatatgc agagaatttg aaaataaatt taataatgag tcagggatgc aaccatattt
    15721 gtttttctct aaagaattaa tgataggaac tgggaaatta atatattcta catttatatt
    15781 tttagcaata tttataggtt taattttctt tgttactaca agtagttttt tatataataa
    15841 attttatatg gattgccaag ttgataagaa aaagtatgag caattaaata aattggggat
    15901 gacatataat gagattaaaa aagcttcaac aattgagatt ggaatagtat ttttgtttcc
    15961 ttatgtagtg gctgttatac attcaatatt tgcccttact gcactgaaaa attcttttga
    16021 tatagaagta gcatcatcag ctgttttggt aatgggaagc ttgttcttgg ttcaaatagt
    16081 ttatttttta attgtaagaa ataattattt aaaagagata aggttaaatt tagtcaattt
    16141 ttagttacta ttattaaatg ataataaaaa gggtttaaaa ttaattaata ttactggaat
    16201 tatagatgtt tattttttca gta
//
LOCUS       DAMJYN010000082        15959 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.086, whole genome shotgun sequence.
ACCESSION   DAMJYN010000082 DAMJYN010000000
VERSION     DAMJYN010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15959)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15959)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15959
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.086"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            235..384
                     /gene="rpmG"
                     /locus_tag="PC466_002924"
     CDS             235..384
                     /gene="rpmG"
                     /locus_tag="PC466_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004402360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HDF2770288.1"
                     /translation="MRVKVTLACTECKQRNYNTTKNKKNNPDRIELQKYCRFCKKHTT
                     HKETK"
     gene            410..631
                     /gene="secE"
                     /locus_tag="PC466_002925"
     CDS             410..631
                     /gene="secE"
                     /locus_tag="PC466_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HDF2770289.1"
                     /translation="MAAQKNDGAKTKKRFSLFGYLKETKQELKRVTWPTKKELFKNTS
                     IVLTVVISCTILVWGIDTILSGALALLLK"
     gene            651..1193
                     /gene="nusG"
                     /locus_tag="PC466_002926"
     CDS             651..1193
                     /gene="nusG"
                     /locus_tag="PC466_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination factor
                     NusG"
                     /protein_id="HDF2770290.1"
                     /translation="MSELQEASWYVVHTYSGHENKVKATIEKAVKTRGMEDCIRQVVV
                     PTEEVVETTKTGKEKTRQRKVYPSYVLVKMIITDESWYVVRNTKGVTGFVGPGSKPVP
                     LSEDEVKAMGIDTTDPKVVNSDVDFEIGDTVKVSQGPFSGQIGNIEEIDLENREVKVC
                     INAFGKRTLFVIELEGIEKI"
     gene            1229..1654
                     /gene="rplK"
                     /locus_tag="PC466_002927"
     CDS             1229..1654
                     /gene="rplK"
                     /locus_tag="PC466_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012158357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HDF2770291.1"
                     /translation="MAKKVIGQIKLQIPAGKATPAPPVGPALGQHGVNIMGFTKEFNA
                     KTADQAGMIIPVVITVYQDRSFSFITKTPPAAVLIKKALNLKSGSGEPNKKKVAKMTS
                     AQVREIAELKMPDLNAASVEAAMSMIAGTARSMGVVIED"
     gene            1724..2422
                     /gene="rplA"
                     /locus_tag="PC466_002928"
     CDS             1724..2422
                     /gene="rplA"
                     /locus_tag="PC466_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HDF2770292.1"
                     /translation="MAKKGKRYAGALQKVDRTKFYDASEALTLVSDIAGAKFDETVEA
                     HIKLGVDSRHADQQVRGAVVLPHGTGKTKRVLVFAKGEKAKEAEQAGADFVGAEELVQ
                     KIQGENWFDFDIVVATPDMMGVVGRLGRVLGPKGLMPNPKSGTVTFDVAKAIDEIKAG
                     KVEYRLDKTNIIHVPVGKVSFGGEKLTENFTALMDAIIKAKPAAAKGQYLRSITVASS
                     MGPGVKINPARTAE"
     misc_feature    2474..2602
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            2645..3151
                     /locus_tag="PC466_002929"
     CDS             2645..3151
                     /locus_tag="PC466_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HDF2770293.1"
                     /translation="MRKAIEIKSEVVSEIVEKLQKSSAAVVVDYKGLTVEEVTELRKQ
                     MREAGVDYKVYKNTLVRRAAKEVGIEQFNDELLVGTNAIAFGYDDPVAPARILKGFMD
                     SHPKMKLKMGIVEGAFYDESKIVEMANIPSREVLIAKLLGSLKAPVSNFAYLIDAIAK
                     KAEGQEEA"
     gene            3209..3574
                     /gene="rplL"
                     /locus_tag="PC466_002930"
     CDS             3209..3574
                     /gene="rplL"
                     /locus_tag="PC466_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000159736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HDF2770294.1"
                     /translation="MTIEQILEAIENMKVLELNELVKAAEEKFGVSASAPVMVAGAAA
                     GGPAAEEKTEFDVVLTDVGSSKVGVIKAVREITGLGLKEAKEVVDNAPKTVKEGASKE
                     EADQIKEKLEAAGAKVEVK"
     gene            3966..4754
                     /locus_tag="PC466_002931"
     CDS             3966..4754
                     /locus_tag="PC466_002931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDF2770295.1"
                     /translation="MEKLQGKIAVVTAATKGIGLASAEILAKNGATVYLAARSEELAN
                     EVINKISAEGGCAKFVYFNAREEETFTSMIEEVVKKEGKIDILVNNFGSTNPSLDKDL
                     VTGDTDNFFDTVNTNLKSVYLPCKAAIPHMIKNGKGSIVNISSIGSVLPDLSRIAYCV
                     SKAAINSLTQNIATQYAKDNVRCNAVLPGLIATKAALDNMSPEFIKEFLKHVPLNRIG
                     EPDDIAKAVLFYASDDSSFITGDLLEVAGGFGLPTPQFADNILG"
     gene            5225..8941
                     /locus_tag="PC466_002932"
     CDS             5225..8941
                     /locus_tag="PC466_002932"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HDF2770296.1"
                     /translation="MPHPVTIGKRTRMSFSKIKEIADVPNLIEIQVDSYEWFLKEGLK
                     EVFDDISPIEDYTGNLILEFVDYSLDDKPKYDIEECKERDATYCAPLKVKVRLINKET
                     GEIKEQEVFMGDFPLMTERGTFVINGAERVIVSQLVRSPGVYYAEERDKTGKRLISST
                     VIPNRGAWLEYETDSNDVISVRVDRTRKQPVTVLLRALGIGTDAEIIDLLGEDERLSA
                     TLEKDNTKTVEEGLVEIYKKLRPGEPPTVESASSLLNALFFDPKRYDLAKVGRYKFNK
                     KLALCYRIMNKISAEDIINPETGEVFVKAGEKISYDLAKAIQNAGINVVNLLMDDDKK
                     VRVIGNNFVDIKSHIDFDIDDLNIKEKVHYPTLKEILDGYSDEEEIKEAIKSRIKELI
                     PKHILLDDIIASISYEFNIFYNIGNIDDIDHLGNRRIRSVGELLQNQVRIGLSRMERV
                     IKERMTVQDMEAITPQALVNIRPVSAAIKEFFGSSQLSQFMDQTNPLSELTHKRRLSA
                     LGPGGLSRERAGFEVRDVHHSHYGRMCPIETPEGPNIGLINSLGTYAKINEFGFIESP
                     YRKFDKETSTVTDEIHYLTADEEDLFVRAQANEPLTEDGKFVNHRVVCRTVNGAVEMV
                     PESRVDYMDISPKQVVSVATAMIPFLENDDANRALMGANMQRQAVPLVRREAPIIGTG
                     IEYRAAKDSGAVVVARNSGIAERVTADEIIIKREDGNRDRYNLLKFKRSNSGTCINQT
                     PIINKGDQIIKGDVIADGPATDLGEVALGRNCLIAFMTWEGYNYEDAILINERLVKED
                     RLSTIHIEEYECEARDTKLGPEEITRDIPNVGDSAIKNLDDRGIIRIGAEVDSGDILV
                     GKVTPKGETELTAEERLLRAIFGEKAREVRDTSLKVPHGESGIIVDVKVFTRENGDDL
                     SPGVNELVRCYIAKKRKIKVGDKMAGRHGNKGVISRVLPEEDMPFMENGTPLDIILNP
                     QGIPSRMNIGQVLEVHLGLAAKTLGWYVATSVFDGANEYDIMDALEEAGYPRDGKLTL
                     YDGRTGQSFDNRITVGYMYYLKLHHLVDEKLHARSTGPYSLVTQQPLGGKAQFGGQRF
                     GEMEVWALEAYGAAHILQEILTVKSDDVVGRVRTYEAIVKGENIPEPGIPESFKVLIK
                     ELQSLCLDVKVLTDEDQEIEVRESVDEDDTIGEFELDVVNHMGEVEESNIIEEIEDDF
                     VEATEDEDIENLEEFTEDDLFEEEIDFESDDFDM"
     gene            8983..12468
                     /gene="rpoC"
                     /locus_tag="PC466_002933"
     CDS             8983..12468
                     /gene="rpoC"
                     /locus_tag="PC466_002933"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HDF2770297.1"
                     /translation="MFELNNFESIKIALASPEKIRQWSRGEVKKPETINYRTLKPEKD
                     GLFCERIFGPQKDWECHCGKYRRVRYKGVVCDRCGVEVTKSKVRRERMGHIELAAPMS
                     HIWYFKGIPSRMGLLLDMSPRSLEKILYFASYVVVDPGETGLNEKQLLTEKEYRTALE
                     KYGYTFTVGMGAEAVKTLLQNIDLEQQSKDLRAELKDSTGQKKVRTIRRLEVVEAFKK
                     SGNKPEWMILDAIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRLLELGA
                     PDIIVRNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSDMLKGKQGRFRQNLLGK
                     RVDYSGRSVIVVGPELKFYQCGLPKKMALELFKPFVMDKLVKEGYAHNIKSAKSIVEK
                     VKPEVWDVLEDVIKSHPVLLNRAPTLHRLGIQAFEPILVEGKAIKLHPLVCTAYNADF
                     DGDQMAVHVPLSVEAQAEARFLMLSVNNILAPKDGSPITTPSQDMVLGCYYLTIEAQD
                     GAKGTGMVFKDFNELLLAYYNKSVHLHALVKLKVTLEDGRSSLVESTVGRFIFNENIP
                     QDLGFVDRKENPFALEVDFLADKKSLGKIIDKCFRKHGNTETAELLDYIKALGFKYST
                     LGGITVAVDDMSVPEEKKVFIAEAEAKVDKYEKAYRRGLISDEERYEKVIETWTETTD
                     KVTDALMGGLDRLNNIYIMAHSGARGSKNQIRQLAGMRGLMANASGKTVEIPVKSNFR
                     EGLSVLEYFTSSHGARKGLADTAIRTAESGYLTRRLVDVSQDVIVREIDCGTEDTTEI
                     YAIKEGNEVIEEIYDRIVGRYTIDPILNPETGEVLVEADSMIQEDEAETIVALGIEKI
                     RIRTVLNCKTNHGVCSKCYGRNLATGKEVNIGEAVGIIAAQSIGEPGTQLTMRTFHTG
                     GVAGADITQGLPRVEELFEARKPKGLAVITEVSGRVEIDETGKRKEVNVIPEEGETQT
                     YVIPYGSRLKVKQGQMLEAGDPLTQGFINPHDIVRVNGVKGVQEYIVKEVQRVYRLQG
                     VDVNDKHIEVIVRQMLSKVKVEDPGDTDLLPGGYEDVLTFNECNKDAIDKGLRPAVAK
                     RVLLGITKASLATDSFLSAASFQETTRVLTEAAIKGKEDHLIGLKENVILGKLIPAGT
                     GMKKYRNIAVEKIED"
     gene            12757..13179
                     /gene="rpsL"
                     /locus_tag="PC466_002934"
     CDS             12757..13179
                     /gene="rpsL"
                     /locus_tag="PC466_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HDF2770298.1"
                     /translation="MPTINQLVRKSRKALEKKSTAPALQKGYNSLNKKVTDASAPQKR
                     GVCTSVKTVTPKKPNSALRKVARVRLTNGIEVSAYIPGEGHNLQEHSVVLIRGGRVKD
                     LPGVRYHILRGTLDTAGVDKRRQSRSKYGAKRPKEAKK"
     gene            13302..13772
                     /gene="rpsG"
                     /locus_tag="PC466_002935"
     CDS             13302..13772
                     /gene="rpsG"
                     /locus_tag="PC466_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001137493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HDF2770299.1"
                     /translation="MPRKGNIPKREVLPDPMYGSKVVTKLINNLMVDGKKGKSQRIVY
                     DAFAIVAEKTGEEALEVFNKAMDNIMPVLEVKARRVGGANYQVPIEVRPERRQTLGLR
                     WLVKYTRARGEKGMVEKLAKEIMDAANNTGASVKKKEDTHKMAEANKAFAHYRW"
     gene            13821..15887
                     /gene="fusA"
                     /locus_tag="PC466_002936"
     CDS             13821..15887
                     /gene="fusA"
                     /locus_tag="PC466_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HDF2770300.1"
                     /translation="MARKFPLEKTRNIGIMAHIDAGKTTTTERILFYTGQTHKIGETH
                     EGASQMDWMEQEKERGITITSAATTASWKDHRINIIDTPGHVDFTVEVERSLRVLDGS
                     VAVFCAKGGVEPQSENVWRQAETYGVPRIAFINKMDILGADFYNVISMMKSRLNSNAV
                     PMQLPIGKEDSFIGIIDLLKMDAVIYKDDLGVEMEETDIPEDMKELAAEWREKLVESV
                     AETDEELMMKYLEGEELTIDELKVAIRKATIACEMNPVFCGTAYRNKGVQLVIDAVLD
                     YLPAPTDIPAIKGILADGEEAERHSSDEEPFSALAFKIMTDPFVGKLAFFRVYSGTLE
                     SGSYVLNATKNKRERIGRILQMHANTREEITKVYAGDIAAAVGLKDTTTGDTLCDPAN
                     PIILESMEFPEPVISVAIEPSSKAAQEKMGIALQKLAEEDPTFTVKTDQETGQTIISG
                     MGELHLEIIVDRLLREFKVEAKVGAPQVAYRETITQPVDVEYKYSKQSGGRGQYGHVK
                     IRVAPQEPGEGYKFTNKTVGGSVPKEYVGPVDMGIQGAMQSGIVAGYPVVDVAVELYD
                     GSYHEVDSSEMAFKMAGSMAFKDAMKKGNAVLLEPYFKVEVVTPEDYMGDVMGDLNSR
                     RGLIQGMEARSGAQVINAFVPLSEMFGYSTDLRSSTQGRATYTMIFDHYEQVPASVAK
                     KIAEGK"
BASE COUNT         6246 a         1985 c         3249 g         4479 t
ORIGIN      
        1 atggattaaa aggaataaca aaaagagggg ttaggctcct ctttttttaa catagaaata
       61 caaaaacatt gacacagcat aggattttgt gataacttat acaaggtaat gattatagga
      121 agttaataat atcttgaata ctgtagattt ttaataaata catattttaa agatattata
      181 ttcacatata ttaacaatat atattattgt attacaaagt tggaggtgta tcagatgaga
      241 gttaaagtaa ctttagcatg tacagagtgt aagcaaagaa actacaacac tactaagaat
      301 aagaaaaata atccagacag aatagaatta caaaaatatt gtagattctg taaaaagcat
      361 acaactcata aagaaacaaa atagtttttt ataaggatgt gagtatggaa tggctgccca
      421 aaaaaatgac ggtgcaaaaa ctaaaaaaag gtttagttta tttggatatt taaaagaaac
      481 taagcaagaa ttaaaaagag ttacatggcc gacaaaaaag gaactgttta aaaacacaag
      541 tatagtttta actgtagtta tttcatgcac tatattagta tggggtatag acactatatt
      601 atctggtgca ctagcgttat tactaaaata gacgaaaaga ggtaagttaa atgtcagaat
      661 tacaagaagc aagttggtat gtagttcata cctattcggg acatgaaaat aaagttaaag
      721 ctacaattga gaaagcagtt aaaacaagag gtatggaaga ctgcataaga caagtagttg
      781 ttccaacaga agaggtagtg gaaactacta aaactggaaa agaaaaaact agacaacgta
      841 aagtttatcc aagttatgtc ttggttaaaa tgataataac tgatgaatct tggtatgtag
      901 taagaaatac taagggagtt acaggtttcg ttggacctgg ttcaaaacca gtaccattaa
      961 gtgaagatga agtcaaagct atggggatag atacaacaga ccctaaagta gtaaatagcg
     1021 atgttgattt tgaaatagga gacacagtaa aagtatctca aggaccattt agtggacaaa
     1081 taggtaacat agaagaaatt gacttagaaa atagagaagt caaagtatgc ataaatgcat
     1141 ttggtaaaag gactctattt gtaatagagc ttgaaggtat agaaaaaatc taatactata
     1201 tagaaaaatc tgaggaggtg cgctcaaaat ggctaaaaaa gttataggtc aaataaaatt
     1261 acaaatacct gcaggaaagg ctactccagc gccaccagtt ggaccagcat taggacaaca
     1321 tggtgttaat ataatgggat tcacaaaaga atttaatgct aaaactgcag atcaagctgg
     1381 aatgataata ccagttgtta taactgtata tcaagataga tcattcagtt ttataacaaa
     1441 aactccacca gctgcagttt taattaaaaa agcattaaac ttaaaatcag gttctggaga
     1501 accaaacaaa aagaaagttg ctaaaatgac ttcagctcaa gtaagagaaa tagctgagtt
     1561 aaaaatgcct gacttaaatg ctgcatcagt agaagctgct atgagtatga tagctggtac
     1621 tgctagaagc atgggtgttg taatcgaaga ctaattaaaa gatacacttt ttttataaag
     1681 tgggaggcga gaagccgaaa ttaaccacaa ggaggaaaat aaaatggcta aaaaaggtaa
     1741 aagatatgca ggtgcattac aaaaagtaga tagaactaaa ttttatgatg catcagaagc
     1801 attaacatta gtttcagata tagctggagc taaatttgat gagacagtag aagcacacat
     1861 taaattaggt gttgactcaa gacatgctga ccaacaagta agaggtgcag ttgtattacc
     1921 tcatggaact ggtaaaacaa aaagagtttt agtttttgct aaaggtgaaa aagctaaaga
     1981 agctgaacaa gctggtgctg actttgtagg agctgaagaa ttagttcaaa aaatacaagg
     2041 tgaaaactgg tttgactttg atatagtagt tgctactcca gatatgatgg gtgtagtagg
     2101 tagattaggt agagtattag gacctaaagg tttaatgcca aaccctaaat caggaacagt
     2161 tacatttgat gtagctaaag ctatagatga aataaaagct ggtaaagttg aatacagatt
     2221 agacaaaact aacataatac acgttccagt aggaaaagta tcatttggtg gagaaaaatt
     2281 aactgaaaac tttactgcat taatggatgc tataataaaa gctaaaccag ctgctgctaa
     2341 aggacaatat ttaagaagta taacagtagc ttcttcaatg ggacctggag ttaaaataaa
     2401 cccagcaaga acagctgaat aataaaactg ttgacacagg ttgacaaaaa tgttattata
     2461 tcacttgtca atgtaaaaaa gaatagattt gccgtagata gtgggtgcga aagcttaata
     2521 tcccgccgag gttttagata aattgagatt actaaagctt ttgatgtcta cttttggcaa
     2581 caaaagcttt ttataatgtt gcggtaaata ttaagcctat ttggtgaagg aggtgcacat
     2641 ctatatgaga aaagctatag aaattaaatc agaagttgtt tctgagatag ttgaaaagtt
     2701 acaaaaatct tctgctgctg ttgttgtaga ttacaaagga ttaacagttg aagaagtaac
     2761 tgagttaaga aaacaaatga gagaagctgg tgtagattac aaagtataca aaaatacttt
     2821 agttagaaga gcagctaaag aagttggtat agagcaattt aatgatgaat tattagttgg
     2881 aactaatgcc atagcatttg gatatgatga tccagttgct ccagctagaa tattaaaagg
     2941 attcatggat tctcatccaa aaatgaaatt aaagatgggt attgtggaag gtgcattcta
     3001 tgatgaatct aagattgttg aaatggctaa cataccatca agagaagttc ttatcgctaa
     3061 attacttggt agcttaaaag ctccagtatc aaacttcgca tacttaatag atgcaatagc
     3121 gaaaaaggca gaaggtcaag aagaagctta attgcttaac taaaaaatta taaatattaa
     3181 tttgaaataa aattcggagg tgctaaaaat gacaatagaa caaatattag aagctataga
     3241 aaatatgaaa gttttagaat taaatgaatt agttaaagct gctgaagaaa aattcggtgt
     3301 atcagcttca gctccagtaa tggtagctgg tgcagctgct ggtggaccag ctgctgaaga
     3361 aaaaactgag tttgatgtag tattaactga cgttggttct tcaaaagttg gagttataaa
     3421 agcagttaga gaaataacag gattaggatt aaaagaagct aaagaagtag ttgacaatgc
     3481 tcctaagaca gttaaagaag gagcttctaa agaagaagct gatcaaataa aagagaaatt
     3541 agaagctgct ggagctaaag tagaagttaa gtagtttctt taaaaagata cccattgggt
     3601 atcttttttt atttataaaa aactataaag aaagtatttg gaattataaa gaaagtgttt
     3661 ttataaaata aaaaaaattt atataatagt actaaattaa gggtatcata tatggtgtaa
     3721 tggtatttta atttaacatt attatcaaat taaaatataa acaattgttg taatgtctgt
     3781 atataaagta tataattaaa ctaaaatgta aaattttaca ttttagttta aaaaaataca
     3841 cgagtgtttt ataaataaaa tgtaataaat aattaattaa caaatataaa ttttaaaata
     3901 agttagatat ttagaaaaat cgaaatttgt aggatttaaa ggacatattc aaggaggagt
     3961 taataatgga aaaattacaa ggaaaaattg cagtagttac tgcagcaaca aaaggtattg
     4021 gattagcatc agcagagata ttagcaaaaa atggagcaac tgtgtactta gcagctcgtt
     4081 cagaagaatt agctaatgaa gttataaata aaataagtgc agaaggtggt tgtgctaagt
     4141 ttgtttactt taatgctcgt gaagaagaga cctttacctc aatgatagaa gaggtagtta
     4201 aaaaagaagg taagatagat atacttgtaa acaattttgg ttcaacaaac ccttctcttg
     4261 acaaagacct tgtaactggg gatacagata atttctttga cacagtaaat actaatttaa
     4321 aaagtgtgta tttaccatgt aaagcagcaa ttcctcatat gataaagaat ggaaaaggaa
     4381 gtatagtaaa tatatcaagt ataggttcag tattacctga tttatctaga atagcttact
     4441 gtgtatcaaa agcagcaatc aactcattaa ctcaaaacat agctacacaa tatgctaaag
     4501 acaatgttag atgtaatgct gtacttccag ggcttattgc aactaaagca gcattagaca
     4561 atatgtctcc agagttcata aaagaatttt taaagcatgt tcctttaaat cgtatagggg
     4621 aaccagatga tatagcaaaa gctgttctat tctatgctag tgatgactca tcatttataa
     4681 caggggattt acttgaagtt gcaggaggat ttggtttacc tactccacaa tttgcagata
     4741 atatattagg ataattaaat tactaatatg caatgaaagc ttatgcatta gttatagtag
     4801 aaatgatatt tttataaagg ccatagatat aatttatatt ggaaaggttt gaggttcaaa
     4861 attccaagtt aaatttattt atggtcttta ttttgtatat tttaataaat tgtatatatt
     4921 tgtataaatg taattattta caatcatttt aatatggaat tataattaaa taggggggat
     4981 ggtacttgta taaaattttt tatagaaaat tagacctata aatgaaaaat atggatttta
     5041 tattggaaaa ttgtacataa tacataatat atgcttaaaa taatttacaa aaaatcaaaa
     5101 ataatgcata gtttacatat aagataaaaa atatattgaa aaatacttga cattatgcta
     5161 aaattattag atgcgttaga atgaactatt gttttatttt taattattga gaggtgaaaa
     5221 gtgaatgcca catcctgtca cgataggtaa aagaactaga atgagctttt ctaaaattaa
     5281 ggaaatagct gatgtgccaa atcttataga aattcaagta gattcctatg agtggttttt
     5341 aaaagaaggt ttaaaagaag tgtttgatga tatttcacca atagaagatt atactggtaa
     5401 tcttatattg gaatttgtcg actattctct agatgataaa ccaaagtacg atatagaaga
     5461 gtgtaaagag agagatgcta catattgtgc acctctaaag gttaaggtaa gacttataaa
     5521 taaagaaaca ggtgagataa aagaacaaga agtgtttatg ggtgacttcc ctttaatgac
     5581 agaaagagga actttcgtta taaatggagc agaaagagtt atagtaagtc aattagttag
     5641 atctcctggt gtttactatg cggaagaaag agataaaaca ggtaagagat tgatttcatc
     5701 tactgtaatt cctaatagag gagcatggtt agaatatgaa acagattcta atgatgtaat
     5761 atctgtaaga gttgatagaa caagaaaaca accagttaca gttttactta gagctttagg
     5821 aataggaaca gatgcagaga taattgacct tttaggagaa gatgagagat tatctgctac
     5881 attagaaaaa gataatacta agacagtaga agaaggtctt gtagagatat acaaaaaatt
     5941 aagaccaggt gaacctccta ctgtagaaag tgcatcatct ttattaaatg ctttattctt
     6001 tgacccaaaa agatatgacc tagcaaaagt tggtagatat aaattcaata agaaacttgc
     6061 tttatgttat agaataatga ataaaatttc agcagaagac ataataaatc cagaaactgg
     6121 agaagtattt gtaaaagctg gagaaaaaat aagctatgat ttggctaaag ccatacaaaa
     6181 tgcaggtata aatgtagtaa atctactaat ggatgatgat aaaaaagtta gagttatagg
     6241 aaataatttt gtggatatta agtctcacat tgattttgac atagatgatt taaacataaa
     6301 agaaaaagta cattatccaa ctttaaaaga aattttagat ggatatagtg atgaagaaga
     6361 aataaaagag gctataaaat caagaattaa agaacttata ccaaaacata tattattaga
     6421 tgatataata gcttcaataa gttatgagtt caatatattc tataatatag gaaatattga
     6481 tgatatagat cacctaggaa acagaagaat aagatctgta ggtgaattgt tacaaaatca
     6541 agttagaatt ggtctttcaa gaatggaaag agttataaaa gaaagaatga cggttcaaga
     6601 tatggaagct ataacgcctc aagcgttagt taacataaga ccagtttcag ctgcaataaa
     6661 agaatttttt ggtagttctc agttatctca gttcatggat caaacaaatc ctctatctga
     6721 gttaacgcat aagagaagat tatcagccct tgggcctgga ggtctttcaa gagaaagagc
     6781 tggattcgaa gtgcgtgacg ttcaccattc acactatggt agaatgtgtc caatagagac
     6841 tccagaggga ccaaatatcg gtcttataaa ctctctagga acttatgcaa aaataaatga
     6901 atttggattt atagaatcac catatagaaa atttgataaa gaaacatcaa cagttactga
     6961 tgaaatacat tatttaactg ctgacgaaga agatttattc gtaagagctc aggcaaatga
     7021 gccattaaca gaagatggta aattcgtaaa ccatagagtt gtttgtagaa ctgtaaatgg
     7081 tgctgttgaa atggttcctg aaagtagagt agattacatg gatatatctc ctaagcaggt
     7141 tgtatctgtt gccactgcta tgataccttt cttagaaaat gatgatgcca accgtgccct
     7201 tatgggagcg aacatgcagc gtcaggcagt gcctctagtt agaagagaag caccaattat
     7261 aggaactggt atagaataca gagcagcaaa agactctgga gcagttgttg ttgctagaaa
     7321 ttctggtata gcagaaagag taacagcaga tgaaataatt ataaaaagag aagatggaaa
     7381 cagagataga tataatctac ttaagtttaa acgttcaaac tcaggtactt gtataaatca
     7441 aacacctata ataaataagg gtgaccagat aataaaaggt gatgttatag cagatggtcc
     7501 agcaactgat ttaggagaag ttgcacttgg aagaaactgt cttatagcat tcatgacttg
     7561 ggaaggttat aactacgagg atgctatatt aataaatgaa agattagtta aagaagatag
     7621 attatcaaca attcatatag aagaatatga atgtgaagct agagatacaa aactagggcc
     7681 agaggaaata actagagata tacctaatgt tggagatagt gcaatcaaaa acttagatga
     7741 tagaggtata ataagaatag gtgcagaagt agactcaggt gatatattag ttggtaaggt
     7801 aactccaaaa ggagaaactg aacttactgc tgaggaaaga ttacttcgtg cgatattcgg
     7861 agaaaaagcc agggaagtta gagatacttc acttaaagta cctcatggtg aatctggtat
     7921 aatagttgat gtaaaagtat ttactagaga aaatggagat gatttatctc caggagtaaa
     7981 tgaattagta agatgttata tagctaaaaa gagaaagata aaagttggag ataagatggc
     8041 tggtcgtcat ggtaataaag gggttatctc gagagtatta cctgaagaag atatgccatt
     8101 catggaaaat ggaacgccat tagatataat acttaaccca caaggtatac catcacgtat
     8161 gaacatcggt caggttctag aagttcattt aggacttgct gctaagacat taggatggta
     8221 tgtagcaaca tcagtattcg atggtgctaa tgagtatgac ataatggatg ctcttgaaga
     8281 agctggatat cctagagatg gtaaattaac tttatatgat ggtagaacag gtcaatcttt
     8341 tgacaataga ataactgttg gatatatgta ttacttgaaa ctacatcact tagtagatga
     8401 aaaactacat gcaagaagta ctggaccata ctcattagtt actcaacagc cactaggtgg
     8461 taaagcacaa tttggtggac aaagatttgg agagatggag gtttgggctc tagaagcata
     8521 tggagcggct cacatacttc aagagatact tactgttaag tctgatgatg ttgtaggtcg
     8581 tgttagaact tatgaagcta tagttaaagg tgaaaacata cctgagccag gaatcccaga
     8641 atcatttaag gttcttataa aggaacttca aagtttatgc ttagatgtaa aagtattgac
     8701 agatgaagac caagaaatag aagtaagaga atctgtagat gaagatgata cgataggtga
     8761 atttgagcta gacgttgtaa atcacatggg agaagttgaa gaaagtaata taatagaaga
     8821 aattgaagat gattttgtgg aagccacaga agatgaggat atagagaatt tagaagaatt
     8881 cactgaagat gatttatttg aagaagaaat agattttgaa agtgatgact ttgatatgta
     8941 aatttaatta atgtaaatct caaatagaag ggagagaact ccttgtttga attaaacaat
     9001 ttcgagtcga taaaaatagc attggcttct ccagaaaaaa taagacaatg gtctagagga
     9061 gaagttaaaa agccagaaac tataaattac cgtactttaa agccagaaaa agatggtctt
     9121 ttctgtgaaa ggatatttgg accacaaaaa gactgggagt gtcattgtgg taaatataga
     9181 agagttagat ataaaggtgt agtttgtgat agatgtggag tagaagtaac taaatcaaaa
     9241 gtaagaagag agagaatggg acatatagag ctagctgctc ctatgtctca catctggtac
     9301 ttcaaaggta taccaagtag aatgggactt ttacttgata tgtcaccaag atcgttagaa
     9361 aaaatactat atttcgcctc atatgtagta gttgatccag gtgaaactgg attgaatgaa
     9421 aaacagttac ttacagaaaa agaatacaga actgctcttg aaaagtatgg atatactttt
     9481 actgtgggta tgggtgctga agctgtaaaa acattactac aaaatataga tttagaacaa
     9541 caaagtaaag acttaagagc ggaattaaaa gatagtacag gacaaaagaa agtaagaaca
     9601 attagaagat tagaagttgt agaagcattt aaaaaatctg gaaataaacc agaatggatg
     9661 attttagatg caataccagt aataccgcca gatttaagac caatggtaca acttgatggt
     9721 ggaagatttg caacttcaga cctaaatgat ttatacagaa gagttataaa tagaaataat
     9781 agacttaaaa gactattaga gcttggagct ccagatataa ttgtaagaaa tgaaaaaaga
     9841 atgcttcaag aagctgttga tgcattgata gataatggta gaagaggtag acctgtaaca
     9901 ggacctggaa atagaccact taaatcttta tcagatatgt taaaaggtaa gcaaggtcgt
     9961 ttccgtcaaa acttacttgg taagcgtgtt gactactcag gacgttctgt tatagttgtt
    10021 ggaccagaac ttaaatttta tcaatgtgga cttccaaaga agatggcatt agaattattc
    10081 aagccatttg ttatggataa attagttaaa gaaggttatg cacataatat aaaaagtgcg
    10141 aaatctatag tagaaaaagt taagccagaa gtttgggatg ttttagaaga tgttataaaa
    10201 agtcatccag ttcttcttaa ccgtgcaccg actctacata gattaggtat acaagcattt
    10261 gaaccaatct tagttgaagg taaggctata aaactacatc ctcttgtatg tacagcttat
    10321 aatgcagact ttgatggtga ccaaatggca gtccatgtac ctttatcagt agaagcacaa
    10381 gcagaagcaa gattcttaat gctttctgta aataatatac ttgctcctaa agatggttca
    10441 cctataacta ctccatctca ggatatggtt ttaggttgct attatctaac aatagaagcc
    10501 caagatggag ctaaaggaac aggtatggta tttaaagact ttaatgaact attacttgct
    10561 tattacaata aatcagttca tctacatgca ttagtgaaac tgaaggtaac acttgaagat
    10621 ggaagaagtt cattggttga aagtactgtt ggtagattta tatttaatga aaatatacct
    10681 caagacttag gttttgtaga tagaaaagaa aatccatttg cacttgaagt tgatttctta
    10741 gcagataaaa aatctcttgg taaaataata gataaatgct ttagaaaaca cggaaataca
    10801 gaaacagctg aattactaga ttatataaaa gctctaggat ttaaatattc tacattaggt
    10861 ggtataacag ttgctgttga tgatatgagt gtcccagaag aaaagaaagt atttatagct
    10921 gaggcagaag ctaaagttga taagtatgaa aaagcataca gaagaggtct aatctctgat
    10981 gaagaaagat atgaaaaagt tatagagaca tggacagaaa caactgataa agttactgat
    11041 gctcttatgg gtggactaga tagattaaat aatatatata taatggcaca ttcaggagcc
    11101 agaggttcta aaaaccaaat tagacagctg gcaggtatgc gtggtcttat ggcaaatgca
    11161 tctggtaaaa cagtcgagat accagttaaa tctaatttcc gtgaaggttt atcagtacta
    11221 gaatacttta catcttcaca tggtgccaga aaaggtcttg ccgatacagc tatacgtaca
    11281 gctgaatctg gatatttaac aagaagactt gttgatgtaa gtcaagatgt tattgtaagg
    11341 gaaatagatt gtggaacaga agatactaca gagatttatg ctataaaaga aggaaatgaa
    11401 gttatagaag agatatatga tagaattgta ggaagatata ctatagaccc tatattaaat
    11461 cctgaaactg gagaagttct agttgaggct gattcaatga tacaagaaga tgaagcagaa
    11521 actatagtag ctttagggat tgaaaaaatt aggataagaa cagttcttaa ctgtaaaact
    11581 aatcatggag tttgttctaa gtgttatggt agaaacttgg caacaggaaa agaagttaat
    11641 ataggtgaag cagttggtat aatagcagct caatctatcg gtgagccggg tactcagctt
    11701 acaatgcgta cattccatac tggaggagtt gcaggagctg atataactca aggtctacca
    11761 agggttgaag aattatttga agctagaaaa ccaaaaggat tagctgtaat aactgaagta
    11821 tctggtagag ttgaaattga tgaaacagga aagagaaaag aagtaaatgt aataccagaa
    11881 gaaggcgaga ctcaaacata tgtaattcca tatggttcta gattaaaagt taagcaaggt
    11941 caaatgctag aggctggaga ccctctaaca caaggattta taaatcctca tgatatagta
    12001 agagtaaatg gtgttaaggg agttcaagaa tatatagtta aagaagttca aagagtgtat
    12061 agacttcaag gggttgatgt taatgataag catatagaag ttatagtaag acaaatgcta
    12121 tctaaagtaa aagttgaaga cccaggagat acagatttat tgccaggtgg atatgaagat
    12181 gtattaacat tcaatgaatg taataaagat gctatagata aaggtctaag accagcagtt
    12241 gctaaaagag ttttacttgg tataactaaa gcatctcttg caactgattc attcttatca
    12301 gcagcttctt tccaagaaac aacaagagta ttaacagagg cagcaataaa aggtaaagaa
    12361 gaccacttaa taggacttaa agaaaatgtt atattaggta agttaatacc agcaggaaca
    12421 ggaatgaaga aatatagaaa tatagctgtt gaaaaaattg aagattaata gcatatagag
    12481 taaagaaatc ttgacaacca ttatttgtgg tgttaaaata gtaaagtgtg ttgtttaaaa
    12541 gtacactaag ggcttgaaca agttcttagt gacttttaga tggcaataaa tgagaactaa
    12601 aaagcatcaa gctagaaaag tgctaatatc acatatttat gtgttataga cattaaattg
    12661 taagtaacga atgttacaat cagtcagtat gaatattcat attgatgtag ttggcggtca
    12721 ctgataagat cgaaaatttg gaaggaggtg cagatgatgc caacaattaa ccaattagtt
    12781 cgtaaaagta gaaaagcgct agagaagaaa tctactgctc cagcattaca aaaaggttac
    12841 aactctttaa ataagaaagt aactgacgct agtgccccac aaaaaagagg ggtttgtact
    12901 tcagtaaaaa cagttactcc taagaagcct aactcagctt taagaaaagt tgccagagtt
    12961 agattaacta atggtataga agtttctgct tatataccag gagaaggaca caacttacaa
    13021 gagcatagtg ttgttcttat aagaggagga agagtaaaag accttccagg ggttagatac
    13081 catatactaa gaggtactct agatacagca ggtgttgata agagaagaca atcaagatct
    13141 aaatacggtg cgaagagacc taaagaagct aaaaaataaa acaattaatg attgattata
    13201 gttcggtgct ttaaatatat atatatttac ggcatcacgg cattaaatga tttatgtcga
    13261 gtacctatga tttaagttaa ataattaagg agggaagcga aatgccaaga aaaggtaata
    13321 ttccaaaaag agaagtttta ccagatccta tgtatgggag taaggtagtt actaaattaa
    13381 taaataatct aatggtagac ggaaaaaaag gaaagtctca aagaatagtt tatgatgctt
    13441 tcgcaattgt tgctgaaaag acaggagaag aagctttaga agtatttaat aaagcaatgg
    13501 ataatataat gcctgtttta gaagtaaaag caagaagagt tggtggggca aattaccaag
    13561 tgccaatcga agttagacct gaaagaagac aaacattagg tttaagatgg ctagtaaaat
    13621 atactagagc tcgtggagaa aaaggaatgg ttgaaaagct agctaaagag ataatggacg
    13681 cagctaacaa cactggagct tcagttaaga aaaaagaaga tactcataaa atggcagaag
    13741 ctaataaagc atttgctcat tacagatggt aggatatata gatatcttat aaattcaagg
    13801 atatcataag gaggataacc atggctagaa agtttccttt ggaaaaaact aggaatatag
    13861 gaatcatggc tcatatagat gcaggaaaga ctactactac agaaagaatc ctgttttata
    13921 ctgggcaaac tcataaaata ggagaaactc atgaaggagc ttctcaaatg gactggatgg
    13981 agcaagaaaa ggaaagaggt ataacaataa cttctgccgc tactactgct tcatggaaag
    14041 accatagaat aaacataata gatactcctg gacacgtgga cttcacagtt gaggttgaaa
    14101 gatctctaag agttcttgat ggttcagttg ctgtattctg tgcaaaaggt ggggttgagc
    14161 ctcaatctga aaatgtatgg agacaagctg aaacttatgg agtacctaga atagctttta
    14221 taaacaaaat ggatatatta ggtgcagatt tctacaatgt tataagcatg atgaaatcta
    14281 gattaaattc taatgcagtt cctatgcaat taccaatagg taaagaagat tcatttatag
    14341 gtataataga cttattaaaa atggatgctg ttatatacaa agacgaccta ggggttgaaa
    14401 tggaagaaac agatatacca gaagatatga aagaattagc tgctgagtgg agagaaaaat
    14461 tagttgaatc agtagctgaa actgatgaag aattaatgat gaaatacctt gaaggtgaag
    14521 aacttactat agatgaatta aaagttgcta taagaaaagc tactatagct tgtgaaatga
    14581 acccagtttt ctgtggtaca gcttatagaa acaaaggtgt tcagttagta atagatgcag
    14641 ttttagatta cttaccagca ccaactgata taccagctat aaaaggtata ttagcagatg
    14701 gagaagaagc tgaaagacat tcttctgatg aagagccatt ctctgcatta gcattcaaaa
    14761 taatgactga cccattcgtt ggaaaactag cgttcttcag agtttattct ggaacattag
    14821 aatcaggttc ttatgtttta aatgcaacta agaataagag agaaagaatt ggtcgtatat
    14881 tacaaatgca tgctaataca agagaagaaa taactaaagt gtatgctgga gatatagcag
    14941 cagcagtagg attaaaagat actactactg gagacacatt atgtgaccct gctaatccaa
    15001 taatacttga atctatggaa ttccctgagc cagttatatc tgttgctata gaaccaagtt
    15061 ctaaagcagc tcaagaaaaa atgggtatag ctcttcaaaa attagctgaa gaagacccaa
    15121 ctttcacagt taagactgac caagaaacag gacaaactat aatatctggt atgggtgaat
    15181 tacacttaga gataatagta gatagattat taagagaatt taaagtagaa gctaaagttg
    15241 gtgcaccaca agttgcatat agagagacta taactcaacc agttgatgtt gaatacaagt
    15301 actctaagca atcaggtggt agaggacaat acggtcacgt taagattaga gttgctcctc
    15361 aagagccagg tgaaggatac aagttcacaa acaaaactgt tggtggatca gtaccaaaag
    15421 aatatgttgg tccagttgac atgggtatac aaggagctat gcaatctggt atagttgctg
    15481 gatatccagt tgtagacgtt gctgttgagt tatatgatgg ttcttaccat gaggttgact
    15541 cttctgagat ggcgtttaag atggctggtt caatggcatt caaagatgct atgaagaaag
    15601 gtaatgcagt tcttttagag ccttacttca aagtagaagt tgttactcca gaagattaca
    15661 tgggagatgt tatgggtgac ttaaactcaa gaagaggatt aatccaaggt atggaagcta
    15721 gaagtggtgc acaagttata aatgcattcg ttccactttc agaaatgttt ggatactcaa
    15781 cagacctaag atcttcaact caaggtcgtg caacttacac aatgatattc gatcactatg
    15841 agcaagttcc agcttcagtt gctaagaaaa tagctgaagg aaaataattt aaaaataatt
    15901 aataatataa atataaaaaa taatcagcta gatgagatat atctcatcta gcacaagat
//
LOCUS       DAMJYN010000083        15486 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.087, whole genome shotgun sequence.
ACCESSION   DAMJYN010000083 DAMJYN010000000
VERSION     DAMJYN010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15486)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15486)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15486
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.087"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            210..1538
                     /locus_tag="PC466_002937"
     CDS             210..1538
                     /locus_tag="PC466_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDF2770301.1"
                     /translation="MGSNELKKTLGVSAALSTVVGSVIGAGVFFKPQAVYTLTGGAPG
                     LGILAWLIAGIITITAGLTAAEVSVAIPKTGGMMVYIKEIYGDKLGFLTGWMQIVLFY
                     PGMMAALGVIFGEQASALIGSPSLLLPIAIGIIVIVAGLNMLGSKTGGVIQTVSTICK
                     LIPLILIMVVGFIKGGGNNPILTPMVGEGLSLGSVLGQVLIAILFAFDGWMNVGTLAG
                     EMKNPGKDLPKAIIGGLSVVMAVYFIINLAYLWVLPANELANYASPASAVAEVIFGSM
                     GGKIISVGILISVFGALNGFLLTGSRVAYTLATDKTLPKYGIFSKLNSAQVPANAIAL
                     VSVIASIYALSGQFNLLTDLAVFATWIFYVLTFIGVMKLRKTHPNIPREYKVPLYPIV
                     PIIAIASGIFVVVNQLCFAGMKTTMISIGGLVITAIGLPVYAYMTRGIKR"
     gene            2293..3126
                     /locus_tag="PC466_002938"
     CDS             2293..3126
                     /locus_tag="PC466_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase"
                     /protein_id="HDF2770302.1"
                     /translation="MRNKKKKINRKKLYLLLSAIVVCLAFIVVGVRVSSLNMKENEIS
                     RNAKLSSSTITDIVSNTSIEVSKGPSKSSGKIAYITIDDGPSKFTDEMIKTLNKYNVK
                     ATFFMIDGNMKEYPQQVKNIIKNGNTAGFHSVSHDIHKLYVTSTSAKEEFDTNDQTFY
                     KITGKHSKVIRIPYGSKPYTPQASYQALVDAGYKIWDWDLDTEDWRSNSSQIVQNVKN
                     HIKNRKGEDKDQLVVLMHEKKQSAEALDSVLKFLSDEGYEFAPVDQNQIPKNYWLRNL
                     E"
     gene            3219..4151
                     /locus_tag="PC466_002939"
     CDS             3219..4151
                     /locus_tag="PC466_002939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HDF2770303.1"
                     /translation="MVGILSLMMVGCNKSLAKVNDVEITKEQYKKTKAVLSATNNYIN
                     GQSLDELEKTLDKKGRNKLENVIISFMVDNELLYQEAKDKGLTPSKSEVDSKYQELED
                     KMNLNTSYKEKMDKAGVDKEYLKQEISRDLAIDKNKKAFEDRINISDNDMEAYYTSHK
                     KDFNVEEVSASQILISTLDKNKKEVSKDKKEALKKKADNILTKIKNGESFESLAKKYS
                     DDKATGKNGGQLGYFTKDDKNAEFTKEVFKLKKNEVSNVFETSYGYHIVKVTDKRERQ
                     KSFNECQSLIRESILNEKYIEHIKKLNEDAKIDR"
     gene            4203..4685
                     /locus_tag="PC466_002940"
     CDS             4203..4685
                     /locus_tag="PC466_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDF2770304.1"
                     /translation="MFKSLKRTKVEKYIIDNKDSFYRIAYSYTKNEEDALDVVQEAMY
                     KALYSVENIKEVNYIKTWFYKILVRTSIDFIRKNRKYNNMTDIDLIDETGEYDKYTDL
                     DLRRALEELPIEYKSIIILRFFEDLKIEEVAIILDENVNTVKTRLYTALKKLKLKIEE
                     "
     gene            4697..5566
                     /locus_tag="PC466_002941"
     CDS             4697..5566
                     /locus_tag="PC466_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HDF2770305.1"
                     /translation="MTSKERLNKLKDEYHKIPIPKKLDTIINHEKIENIYREKNKKVN
                     RLRFKVAIAFACIFTVLVNISPVFADNFSKIPVIGVIVEVITIKNYSLKSENYEAEID
                     IPKIRGLKDKNLEQRLNSSFMEDGKRLYHQFQERMEKIQSSKNKGYKSLSLSYSVKNN
                     SKKFLSIEMTKNEIEASSYVSKAHYTIDKKRQIVLTLPMLFKDDKYIKVISDNIKEQM
                     REQMKKDSTKSYFIDQKKDLPVEDFKTINKYQDFYFNKNEDLVICFDEYEVAPGYMGA
                     VEFVIPYKVIKDL"
     gene            5609..6364
                     /locus_tag="PC466_002942"
     CDS             5609..6364
                     /locus_tag="PC466_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HDF2770306.1"
                     /translation="MTTYKKLKKSIFKISIFSICLLVSLVDINPIFAGSSSNETSNSD
                     TIKVLNAKSLNFKQGNYEVNVSIPKIKGLKDKTLENKLNNEFLQDGKKIYSEFQNKMK
                     KENNKGHRYLNVIHNVKNNSKDFLSIEMTKEEIEDSSSITKKHYTVDKNRGILLNLPI
                     FFKDSRYIRAISDNIKEQMRNQIKKDDTKSYFIDQDKDFPVKDFESINKYQDFYFNKN
                     GNLVISFEEYEVVPGYMGAVEFVIPNKVIKRLR"
     gene            6406..7227
                     /locus_tag="PC466_002943"
     CDS             6406..7227
                     /locus_tag="PC466_002943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XdhC family protein"
                     /protein_id="HDF2770307.1"
                     /translation="MNIYEQAIRLIENNEDFAFATITSHSGSTPRETGAMMIVKNDST
                     IFGSVGGGSVEAECIKHAINVIKNRESMLYKFTLNKSDVAKLGMICGGTGEIQIDFID
                     SKLKSNIEKFNKRLKENTSKAYIFGAGHISRDVAVILSLLEFRTVVIDDREEFANYER
                     FPESEVVVLDSFENIPDFPTDENSYIIILTRGHLYDSSALEWALKRETGYIGMIGSRT
                     KIGLTYEKLMKKGFKKEELSKVHAPIGIKLNAQTPAEIAVCIAAELINCRANKEK"
     gene            7232..7993
                     /locus_tag="PC466_002944"
     CDS             7232..7993
                     /locus_tag="PC466_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M48 family metallopeptidase"
                     /protein_id="HDF2770308.1"
                     /translation="MNTGSKDIDTLNVNFRGIEIKAVLVYKNRKNISIKIDPFGKIIV
                     MSPPKISKKIIKDIIIEKGDWILKKSEKYKGREEVYKQRMFITGEKFLYLGEEYHLVI
                     KELLKDSVKKSNCRITINEYQIVVQTNDTSTDFIKKSLKSWYKMESERTVLERIDFLK
                     LNCEIMKQLVPASVKVKEQNKRWGSCTAQKNIYINSKISMARLDVIDYVIIHEFSHLV
                     HMNHSKKFYDLVKSIMPDYKDKENWLKINGYKIII"
     misc_binding    8154..8411
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            8524..8763
                     /locus_tag="PC466_002945"
     CDS             8524..8763
                     /locus_tag="PC466_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HDF2770309.1"
                     /translation="MENTVYAKLNQGIDSFLRVAMTLRRREVDIQSISMTVDNMNNSG
                     IKLIVNEEKTSLDSVLNHMKKLHDIREITVERMRH"
     gene            9033..10028
                     /gene="ilvC"
                     /locus_tag="PC466_002946"
     CDS             9033..10028
                     /gene="ilvC"
                     /locus_tag="PC466_002946"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HDF2770310.1"
                     /translation="MKMARMYYEKDVDLEVLKNKKVAVLGYGSQGHAHAQNLRDNGVH
                     VVIGLYDGSKSAQKAKEDGFEVKSVAEATKESDLTMMLMPDEKQKKVYEESVKDNLKE
                     GQTLAFAHGFNIHYNQVQPPEFVDVVMVAPKGPGHLVRNVFTKGSGVPALFAVYQDYT
                     KKATETVLAYAKGIGATRAGVLETTFKEETETDLFGEQSVLCGGISELIKLGYKTLVD
                     AGYQKEVAYFECLHEMKLIVDLIYEGGFERMRYSISDTAEYGDYVSGKRVITDAAKQG
                     MQNVLEDIQNGKFAKAWIKENEEGRENFLKTREEEYNTEIAEVGRNLRSMMSFLK"
     gene            10081..11769
                     /gene="ilvB"
                     /locus_tag="PC466_002947"
     CDS             10081..11769
                     /gene="ilvB"
                     /locus_tag="PC466_002947"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biosynthetic-type acetolactate synthase large
                     subunit"
                     /protein_id="HDF2770311.1"
                     /translation="MNGAKVILECLKKEGIDTIFGYPGGAVIPLYDALYDYSDDFKHI
                     RTSHEQGLVHAADGYARSTNTVGVCFTTSGPGATNAITGIATAFMDSSPMVVISGQVP
                     TSLLGKDSFQEIDITGATLSMTKHNYLVRNTKELVPTIKEAFRVANSGRKGPVLVDVP
                     KDLFLAEMDFSGEDYDLCQIDDYMDYKSDFDLDDETNIKLLNEAIDIIKESKKPVIYA
                     GGGVKSSDSEEILEKFATKIDTPVLNTLMGLGNIDRKNELSLGMVGMHGSRESNLALS
                     NSDLVIAIGARFSDRVISKSSEFAKNAKIIHIDIDPSEISKNIESNVSLVGDVKLVLS
                     LLIERVESKNNSNWKEEIKTFRKSEGVQTYEFHPQNILKKINEKYETLKKPTVVVTDV
                     GQHQMWSAKYWNFKGNKSFITSAGLGTMGFGLGAAIGTKAGNVDKNVVLVTGDGSFRM
                     NCNELATVANYNVPMLILLLNNRTLGMVRQWQKLFSNQRYSQTDINENVDYVKLVNAY
                     NIDGYKVSNMEELGKVLDVIDFNKPVFLQCDIDKDYDVYPIVAPNDALENLICN"
     gene            complement(12127..13257)
                     /locus_tag="PC466_002948"
     CDS             complement(12127..13257)
                     /locus_tag="PC466_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDF2770312.1"
                     /translation="MKGGVRKRSNKWYYYFDLGIVEGKRKKVERVGGNTKKEAEKALR
                     EALNEYENSGIVFEESNISLSDYLDFWYKEYVLLNCKYNTQESYRINIEKHIKPKLGA
                     YKVKALTPAILQNFINKKYKEDYSQNTLQVLKAILHRSLKSAVHPYKHIRENPMQYVS
                     IPKTKSKTETNKVKTITLEEFNQILNIFPQDSFQRIVLLIGFHTGMRRGEIIALKWDN
                     IDLDNKTITVKHTLIKKPNGMFELGQPKTESSCRTIFTGDTLIKALKEHKLYQKKMKL
                     KYGEFYFDSDWVCTKENGQQVNTHTLDTIVRQIRVALNNDFHFHSLRHAHATLLLENG
                     ANIKDIQNRLGHSQLSTTMDTYSHVTDKMKNETVDIFEKITN"
     gene            complement(13336..14043)
                     /locus_tag="PC466_002949"
     CDS             complement(13336..14043)
                     /locus_tag="PC466_002949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIRAN domain-containing protein"
                     /protein_id="HDF2770313.1"
                     /translation="MSIKNGKDFLYVIWKDPKSRRQFIIGKLAKNGLYEFSYEYEIDE
                     AIKAGFNALISFDDISKTYYSEDLFSPFASRLPDKKRKDINKILDKYDMSEYDTYELL
                     KRSGARLPIDTLEFVDPIPLDIDKNIIRYFYIAGVRHYAGCEGHECDNSIELESNEAL
                     VLELEPENKFDPHAIKVFDKKENHIGYIPRYYSGELTSIINRGLKYNCIIKFVNKENN
                     CDECIKVKLEILFDEYN"
     gene            complement(14056..14925)
                     /locus_tag="PC466_002950"
     CDS             complement(14056..14925)
                     /locus_tag="PC466_002950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HipA domain-containing protein"
                     /protein_id="HDF2770314.1"
                     /translation="MIKNFDEWKEYDGFSYGSGRSEKIWLINEKTKDIGLFKFPKTKE
                     TGEYWAEKLACEIASLLKIPCANVEIGTYNKRIGSMSYLINKNDEKLIEGVWLINKYY
                     PCYNTDKLYDYKNNEYYSLKMIFKSIEEYNIKNDFLKMLIFDYLIGNRDRHQNNWALL
                     ESQNKITLSPLYDNGSSLCCYVNIENIDSFFTDHQRFEALINTRSRSRIRIDGKNKKE
                     PTHLEVLKYLNSNYYEQTIDFVEKIINLMNEVNINTLIDNYSENIISPKLKKLLKIYL
                     KEKVLRIKNIYNL"
BASE COUNT         6003 a         1689 c         2514 g         5280 t
ORIGIN      
        1 acgtttattt ataaatatta ttatatttgg atttttggtt tttataattt ttttatattt
       61 aaacataact aaaagtaaaa gattacgaaa gctaagtaga gtttatttta ttttaataaa
      121 taaaaaagct atttttctat atattggcat aatatatgct tatttaacta tgaaattaaa
      181 attaaatagg attaatgagg aggaaaagaa tgggaagtaa tgaactgaaa aagactcttg
      241 gcgtatcagc agcattatca actgttgttg gttctgttat aggagcgggc gtatttttta
      301 aaccacaagc agtctataca ttaactggag gagctccagg tcttggtata ttggcatggt
      361 taatagctgg aatcataact ataacagctg gtcttacagc tgcagaagta tcagttgcga
      421 taccaaaaac tggtggaatg atggtatata taaaagaaat ttatggagac aaattaggtt
      481 ttttaactgg atggatgcaa attgtattat tttatccagg gatgatggca gcattaggtg
      541 ttatatttgg agaacaagca tcagcactaa ttggtagccc atcactttta cttccaatag
      601 caattggaat tatagtaata gttgcagggc ttaatatgtt aggttcaaaa actggaggag
      661 tcatacaaac tgtctctaca atttgtaagt taataccact tattttaata atggttgttg
      721 gatttattaa aggtggtgga aataatccaa tacttacacc tatggttggt gaaggattaa
      781 gcctgggtag tgtactaggt caagttttaa ttgctatatt atttgctttt gatggatgga
      841 tgaatgttgg tactttagct ggagaaatga agaatcctgg aaaagacctt ccaaaagcta
      901 taataggtgg attgtcagtt gttatggctg tttattttat aataaattta gcgtatcttt
      961 gggtattacc agctaatgaa ttagcaaatt atgcttctcc tgcatcagca gttgctgaag
     1021 ttatatttgg ttcaatgggt ggaaaaataa tatctgtagg tatattaatt tcagtgtttg
     1081 gagcattaaa tggattttta ctaactggtt caagggtggc atatacttta gctacagata
     1141 agactttacc aaagtatggt atattttcta aattaaattc tgctcaagtt ccagcaaatg
     1201 caatagcatt agtatctgtt attgcatcta tatatgcttt gtcaggtcaa tttaatttat
     1261 taactgactt agctgtattt gctacttgga tattctatgt attaactttt ataggggtta
     1321 tgaaacttag aaagactcat ccaaatatac caagagagta taaagttcca ttatatccta
     1381 ttgttcctat aatagctata gcaagtggta tatttgttgt agttaatcaa ttgtgttttg
     1441 cagggatgaa aactactatg atatctatag gaggtcttgt aataacagct ataggcttac
     1501 cagtgtatgc ttatatgact agaggaataa aaagataaac caagtagttt acaaatgctt
     1561 tataattaaa ataaaagaga ctgtctcaaa atagagataa gtctcttttt tattgttaaa
     1621 agggtaaaga gatgttttat tttataaaaa aagagtgttc tatgaactaa aaagtttatt
     1681 ttaaggtatt cactttattt ttagtttttg aattataaaa ttaaacatct aaaaaattat
     1741 ttgctttaag atactttatt ttaaagtgtt tttttttcaa actaagtgat atctatataa
     1801 caaatattat acataggttt tatgaaaatt aaatctttct gttatataaa atagaatatt
     1861 gtattatata gaaaatatta cctgatcaat atcgtgattt ataaataaga ttagaaaatt
     1921 ttatttgata acaaaaatta gacaatatga atatataatg tatgtattaa aaatgtggca
     1981 aatagttgtt ttggtattta ttatttgttt aatatttcta atttataaaa aaaaaattat
     2041 aaattttaaa aattataaat gacattttaa ctagaattaa ttgtaaaaaa cactatataa
     2101 tactcaattt tcaacattct atacaattat acagaaatta tacagcataa taatcaccga
     2161 aataacaaat tttaaaaatt aagcaaaact ttttgtcgaa gttcaacgtc tatatatatg
     2221 tagtgtaaat ttttgggata aaatactaca aaaatataaa tgtaaaaata tagtaatatt
     2281 ggaggtcgaa cgatgagaaa taaaaagaaa aaaataaata gaaagaagtt gtatttgctt
     2341 ttaagtgcta ttgtagtgtg tctggctttt atagtagttg gtgttcgcgt cagctcttta
     2401 aatatgaagg aaaatgaaat tagtagaaat gcaaaactgt caagttctac tattacagat
     2461 atagtatcta atacatcaat agaagttagt aaagggccaa gtaaaagttc tggaaaaata
     2521 gcatacataa ctatagatga tggcccatct aaatttactg acgagatgat aaaaacttta
     2581 aataaataca atgttaaagc aacttttttt atgatagatg ggaatatgaa ggaatatcca
     2641 cagcaagtta aaaatataat taaaaatggg aacacagcag gttttcatag tgtatcacat
     2701 gatattcaca agctttatgt tactagtaca tcagcaaaag aggaatttga tacaaatgat
     2761 caaacttttt ataagataac tggtaaacat tcaaaagtaa taagaatacc ttatggaagc
     2821 aaaccatata caccacaagc ctcttatcag gctttagttg atgctggata taaaatttgg
     2881 gactgggact tagatacaga agattggaga tctaattctt ctcaaattgt acaaaatgta
     2941 aaaaatcata ttaagaatag aaaaggtgaa gataaagacc aacttgtagt tttaatgcat
     3001 gagaaaaaac agagtgcaga agctttagat tcagttttaa aattcttatc agatgaaggt
     3061 tatgaatttg cgccagtaga tcaaaaccaa ataccaaaaa attattggtt acgtaattta
     3121 gagtagttaa aatataagaa tattgattga tatttttaga aattgagaat aaaaatgagt
     3181 gaggtgtagg tatattgaat aaaaaacttt atataggaat ggtcggaata ttgtctttga
     3241 tgatggttgg ttgtaataaa agtttagcaa aagtaaatga tgtggaaatc acaaaagaac
     3301 agtacaaaaa aacaaaagca gttttatctg ctactaataa ttatataaat gggcagtctt
     3361 tagatgaatt agaaaaaact ttggataaaa aaggtagaaa taaattagaa aatgttataa
     3421 tatcgtttat ggtggataat gaacttttat atcaagaggc taaggataaa ggactaactc
     3481 caagtaaaag tgaagtagac tcaaaatatc aagaactaga agataagatg aatttgaata
     3541 caagctataa ggaaaaaatg gacaaagcag gtgttgataa agaatattta aaacaagaaa
     3601 tatctagaga tttagcaata gataaaaata aaaaggcctt tgaagataga ataaacataa
     3661 gtgataatga tatggaagcc tactatacaa gtcataaaaa agattttaat gtagaagaag
     3721 taagtgcttc tcagatactt atatcgactt tagataaaaa taaaaaagaa gtaagcaaag
     3781 ataaaaaaga agctttgaag aagaaggcag ataatatatt gactaaaatc aaaaatggag
     3841 aaagttttga aagtttagct aaaaaatatt cggatgataa agcaactgga aaaaatggag
     3901 gacagctagg atattttaca aaggatgata aaaatgctga gtttacaaag gaagtgttca
     3961 aattaaagaa aaatgaagtt tcaaatgtgt ttgaaactag ttatggatat catatagtca
     4021 aagttactga taaaagagaa agacaaaaaa gttttaatga gtgtcagagt ttaataagag
     4081 aatctatttt aaatgaaaag tatattgagc atataaaaaa actgaatgaa gatgctaaaa
     4141 tagacagata gaatttctaa cagctcaatc ctagcctgta atcggaggga gattttacag
     4201 gaatgtttaa gagtttaaag agaacgaaag ttgagaaata cattatcgat aataaagact
     4261 ctttttatag aatagcatat agttatacga agaatgaaga agatgcctta gatgtggttc
     4321 aagaagccat gtataaggca ctatactcag tggaaaatat taaagaagta aattatataa
     4381 agacatggtt ttataaaatt ttagttagaa cgagtataga ttttattaga aaaaaccgta
     4441 aatataataa tatgacagat attgacctta tagatgagac tggagagtat gataaatata
     4501 ctgatttgga tttaagaaga gctttggaag aattacctat tgaatacaaa tctattataa
     4561 tattaagatt ttttgaagat ttaaagattg aagaagtagc aataatattg gatgaaaatg
     4621 tgaatactgt taaaactagg ttatatactg ctttaaaaaa actaaaatta aaaattgaag
     4681 agtagggata aaaagaatga caagcaaaga aaggttaaat aagttaaaag atgagtatca
     4741 taaaattcca atacccaaga aattagatac tataataaat catgaaaaaa tagaaaacat
     4801 atatcgagag aaaaataaaa aagtaaatag attaagattt aaagttgcaa tagcctttgc
     4861 atgtatattt acagtattag taaatataag tcctgtattt gcagacaatt tttctaagat
     4921 acctgtaatt ggagtaatag tagaagtaat aactataaaa aattatagtt taaaaagtga
     4981 aaattatgaa gctgagattg atattcctaa aatacgaggt ttaaaagata aaaacttaga
     5041 acaaagatta aacagtagtt ttatggaaga tggaaaaagg ctttatcatc aattccaaga
     5101 gagaatggag aagatacaat catcaaagaa taaaggatat aaatctttaa gtttgagtta
     5161 tagtgtaaaa aataattcta aaaaatttct atcaatagag atgacaaaaa atgagataga
     5221 ggcttcatca tatgtgagta aggcacatta tactattgat aaaaaaagac aaatagtttt
     5281 gactttgcca atgcttttta aagatgataa gtatataaaa gttataagtg ataatataaa
     5341 agaacaaatg agagaacaaa tgaaaaagga tagtacaaaa tcctatttta tagatcaaaa
     5401 aaaagacttg cctgttgaag attttaaaac aattaataag tatcaggatt tttattttaa
     5461 taaaaatgaa gaccttgtaa tttgttttga tgaatatgaa gtagcacctg gttatatggg
     5521 tgcagttgag tttgtaatac catataaagt aataaaagat ttgtaaattg aatagtagtt
     5581 tatatataca tattttaaga aggacaatat gactacatat aaaaagctta aaaaatctat
     5641 atttaaaatt tctatatttt caatatgctt attagtctca ttagtagata taaaccctat
     5701 atttgcaggt agttcctcta atgagacttc aaatagtgat acgataaagg tgttaaatgc
     5761 taagagtctc aactttaaac aaggcaatta tgaagtgaat gtgagtattc ctaaaataaa
     5821 aggtttaaaa gataaaactt tagagaataa attaaacaat gagtttttgc aagatgggaa
     5881 aaaaatttac agtgaatttc aaaataaaat gaaaaaggaa aataataagg gtcatagata
     5941 cctaaatgta atccataatg tcaaaaataa ttctaaggac tttttatcaa tagaaatgac
     6001 aaaagaagag atagaagatt cctcgtctat aactaagaag cattacactg ttgataaaaa
     6061 tagaggaata ctattaaatt taccaatatt ttttaaagat agtagatata ttagagctat
     6121 aagtgataat ataaaagagc agatgagaaa tcaaattaag aaagatgata caaaatctta
     6181 ttttatagac caagataaag acttcccagt gaaagatttt gaatctataa ataagtatca
     6241 agatttttat tttaataaaa atggaaatct tgtgattagt tttgaagaat atgaagtagt
     6301 acctggttat atgggagcag tagaatttgt gataccaaat aaagtaataa aaagactaag
     6361 atagatatat agaagatttt tagatagact ggtaaggaga attatatgaa tatatatgaa
     6421 caagcaataa gattaataga aaataatgaa gatttcgcat ttgctacaat aacgtctcat
     6481 tcaggttcaa caccacgtga aactggagca atgatgattg tgaaaaatga ttctactata
     6541 tttggttcag taggaggagg tagtgtagaa gcagaatgta taaaacatgc aattaatgtt
     6601 ataaaaaata gagaatcaat gttgtataaa tttactctaa acaaatctga tgtggcaaaa
     6661 ctaggaatga tatgtggagg tactggagaa atacaaatag attttataga tagtaaatta
     6721 aaaagtaata tagaaaaatt caataagaga ctaaaggaaa atacaagtaa agcatatata
     6781 tttggtgcag gtcatatttc aagagatgtt gctgtgatac tatctctttt agaatttaga
     6841 acagtagtaa tagatgatag agaagaattt gctaattatg aaaggttccc agaatcagaa
     6901 gtagtagttt tagattcttt tgaaaatata ccagattttc caactgacga aaatagctat
     6961 ataattattt taacaagagg tcatctatat gattcaagtg ctttagaatg ggctcttaaa
     7021 agagaaactg gttatatagg tatgattgga agtagaacaa aaattggatt gacgtacgaa
     7081 aaactcatga aaaaaggttt taagaaggaa gaattatcaa aagtacatgc accaataggc
     7141 ataaaattga atgctcaaac accagctgaa atagctgtat gtatagctgc tgaacttata
     7201 aattgtagag ctaataagga aaaataaact aatgaacaca gggagtaaag atattgatac
     7261 tttaaatgtt aattttagag ggattgaaat aaaagcagtt ttagtatata aaaatagaaa
     7321 aaatatttct ataaaaatag atccatttgg caaaataatt gtaatgagtc ctcctaaaat
     7381 atccaaaaaa ataataaaag atataattat tgaaaaagga gactggatac ttaaaaagtc
     7441 agaaaaatat aaaggaagag aagaagtata caaacaaaga atgtttataa ctggcgaaaa
     7501 atttctttat ttaggtgaag agtaccatct agttataaaa gaactgttga aagattctgt
     7561 caaaaaaagt aactgtagaa taactattaa cgaatatcaa atagttgttc agacaaatga
     7621 tacaagtaca gattttatta aaaaatcttt aaaatcttgg tataagatgg aaagtgaaag
     7681 aacagtatta gagagaatag attttcttaa attaaattgt gaaataatga agcaattagt
     7741 tccagcaagt gttaaggtaa aagaacaaaa taagagatgg ggaagttgta cagctcaaaa
     7801 aaatatttat ataaactcaa aaatatctat ggcaagatta gatgtaattg attatgtaat
     7861 aatacatgag tttagccatt tagtacatat gaatcactct aaaaaattct atgatttagt
     7921 aaaatccatt atgcccgatt ataaagataa agaaaattgg ctaaaaataa atggatataa
     7981 aataataatc tgaaaacgat tattccaaaa tacaggcgta aagtataaaa gaagtattat
     8041 tgtgaaaaaa ataaataatc tgaaaatttt aaaaaaagtc attgacattg taaatgatag
     8101 ggaatataat ctatattaac aacaaaacag aattaaaata taaaattaaa aaattaaaag
     8161 caatgacaga gacaacaata ctaatagtgt tatccacaga gaaccaatgt tgctgagaat
     8221 tggtgttaac agtagtataa tgatcactct ggagcttttg tactgaatat ttttagtaag
     8281 tacaaacgta tgtcaacgtt acatgactaa ggttaaggta attaattacc cgacctgaaa
     8341 aaagaggggt agatgtattt tttatatcta caaataaggt ggtaccgcgg aatataactt
     8401 tcgtccttat aagtaatatt tatattgctt ataaagatga aagttttttt attttaagcg
     8461 atataaataa atttaatcca tataaaatta ataaaaaaat aataaaaata aggagggatt
     8521 tttatggaaa atactgtata tgctaaatta aaccaaggaa tagattcttt tttaagagtg
     8581 gctatgactc taagaagaag agaggttgat atacaatcaa taagtatgac tgtagataat
     8641 atgaataatt caggtataaa attaatagta aatgaagaaa agacatcttt agattctgtc
     8701 ttaaaccata tgaaaaaact acatgatata agagagataa ctgttgaaag aatgagacat
     8761 taattaaata tattttataa agctaaagat aaatattaaa taagaaaaat cttagattaa
     8821 aatataagtg tcattgaatt tatcagttta tcacagttaa taaatttatt agtttgttgt
     8881 agctaataaa aactgaaaat tctaaaatta taattgtaag attatataaa tttagaattt
     8941 aaatctgttg aataatatta aaacaatgat aatgagtatg aatttctaat aaaaataaat
     9001 atcataaaaa taagaaaaag tattgggagg aaatgaaaat ggcaagaatg tattatgaaa
     9061 aagatgtgga tttagaggtt ttaaaaaata aaaaggttgc agttttaggt tatggaagtc
     9121 aaggacatgc acatgcacaa aatcttagag ataacggtgt acatgtagtg ataggtcttt
     9181 atgacggaag taaatcagca caaaaagcaa aagaagatgg atttgaagtt aagagtgtag
     9241 cagaagctac aaaagaaagt gatttgacaa tgatgttaat gcctgatgaa aaacaaaaga
     9301 aagtttatga agagagtgta aaggataact taaaagaagg tcagacatta gcttttgctc
     9361 atggattcaa tatacattat aatcaagtac aaccaccaga atttgttgat gttgtaatgg
     9421 tagctcctaa aggacctggt cacttagtta gaaatgtatt tacaaaggga agtggagttc
     9481 ctgcactatt tgcagtatat caagactaca ctaaaaaagc tacagagaca gttttagcat
     9541 atgcaaaagg gataggagca acaagagcag gtgttttaga aactactttt aaagaagaaa
     9601 cagaaacaga tttatttgga gaacaatcag tactttgtgg tggaataagt gaacttataa
     9661 aattgggata taaaacgctt gtagatgcag gttatcaaaa agaagtagca tactttgaat
     9721 gtttacatga aatgaaacta atagtcgacc ttatatatga aggtggattt gaaagaatga
     9781 gatatagtat aagtgacaca gcagaatatg gagattatgt atctggtaaa agggtaataa
     9841 ctgatgctgc aaaacaaggt atgcaaaatg ttttagagga tatacaaaat ggaaaatttg
     9901 caaaagcgtg gattaaagaa aatgaagaag gacgtgaaaa cttcctaaaa actagagaag
     9961 aagaatataa tacagaaatt gccgaagttg gtagaaatct aagaagtatg atgtcattct
    10021 taaaataaat atatattaaa tggattagtt tgagggaaag agtggtgtat agtagtgcgt
    10081 atgaatggag caaaggtaat tttagaatgt ttaaagaaag agggaattga cacaatattt
    10141 ggatatcctg gtggagccgt gatacctctt tatgatgctc tatacgatta ttcagatgat
    10201 tttaaacata taaggacatc ccatgaacaa ggtttagttc atgctgcaga tgggtacgca
    10261 agaagtacta atacagtagg agtttgtttt acaacatctg gtccaggagc aacaaatgcc
    10321 ataactggaa tagcaacagc ttttatggat tcttcaccta tggttgtaat ttcagggcag
    10381 gtgccaacta gtttattagg aaaagattct tttcaagaaa ttgacataac tggagcaaca
    10441 ttatctatga caaaacataa ttatttagtt agaaacacta aagaattagt tcctacaata
    10501 aaagaagctt ttagagttgc aaattcaggt agaaaaggac ctgtacttgt agatgttcca
    10561 aaagatttat ttttagcaga aatggatttt agtggtgagg actatgattt atgtcaaata
    10621 gatgattata tggattataa gagtgatttt gatctagatg atgaaactaa tattaagctt
    10681 ttaaatgaag caatagatat cataaaagaa tctaaaaagc ctgtaatata tgcaggtgga
    10741 ggtgttaaat cttcagacag tgaggaaatt cttgaaaaat ttgcaactaa gatagataca
    10801 cccgtactaa atacacttat ggggcttgga aatatagata gaaagaatga actatctctt
    10861 ggaatggttg gaatgcatgg aagtagagaa agtaatttag cactttctaa ttcagattta
    10921 gtaatagcga taggtgcgag atttagtgat agagtgataa gtaaaagttc tgaatttgct
    10981 aaaaatgcaa aaataataca catagacata gacccatctg aaataagtaa aaatatagaa
    11041 tctaatgtat ctttggttgg agatgtaaag ctagtcctta gtttattaat tgaaagggtt
    11101 gaaagtaaga ataatagcaa ttggaaagaa gagataaaga catttagaaa gagtgagggt
    11161 gtacaaacat atgaatttca tccacaaaat atacttaaaa aaataaatga aaaatatgaa
    11221 acattaaaga aacccactgt ggtagtaact gatgtcggtc aacatcaaat gtggtctgct
    11281 aaatactgga attttaaagg taataaaagt tttataacat cagcagggtt aggaactatg
    11341 ggatttggtt taggtgcagc tattggaact aaagctggta atgtagataa aaatgtggtt
    11401 ttagtaactg gtgatggaag ttttagaatg aactgtaatg aactagctac agttgcaaat
    11461 tataatgtac ctatgcttat tttactactc aataatagaa cattaggaat ggtaagacaa
    11521 tggcagaagt tattttccaa tcaaagatac tctcaaactg atattaatga aaatgtggat
    11581 tatgttaaac tcgtaaatgc atataatatt gatggatata aggtatccaa tatggaagaa
    11641 ttaggaaagg ttctagatgt gatagatttt aataaacctg tatttttaca atgtgatata
    11701 gataaggatt atgatgttta tcctattgta gcacctaatg atgcattgga aaatttgata
    11761 tgtaactaaa acttatactg aatattgata aaatttttta ttaaattttt attggtattc
    11821 agtttttgtt tagagataga ttggcatttt ttatttttgc aaataaatca atgaatatat
    11881 aattaagaac ttattaaatt ttaattatac aatttagaat agtattacaa cttaagtaaa
    11941 tattaagttt tattcgttag atttattatt aataccttat attagttatg gttgttatat
    12001 actctaaagc cttgaaatta caagcgtata gctgactata taaatttgat aattttagct
    12061 tttaaaatag ataaattaga ttttgccacc catttgccac cgtattatat ttttgggtgg
    12121 caaactctaa tttgtaattt tttcaaatat atctacagtt tcatttttca ttttatcagt
    12181 tacatgtgaa taggtatcca ttgtagttga taattggcta tgacccaaac ggttttgtat
    12241 gtctttaatg ttagcaccat tttctaataa tagagtagca tgtgcatgtc ttaaagaatg
    12301 aaaatggaag tcattgttta aagctactcg aatttgtctt actatagtgt ctaaagtgtg
    12361 agtattcact tgttgaccat tttctttggt acatacccaa tcactatcaa agtaaaattc
    12421 tccgtatttt aatttcattt tcttttgata taatttatgt tcttttaatg cctttattaa
    12481 agtgtcacct gtaaatatag ttctgcaaga gctttctgtt tttggttgcc ctaattcaaa
    12541 cattccattt ggttttttaa tcaaagtatg ctttactgtg atagttttat tatcaaggtc
    12601 tatattatcc cattttagtg caataatttc acctcttcgc ataccagtat gaaatccaat
    12661 tagtaaaact atacgttgaa atgaatcttg aggaaatata tttagtattt gattaaattc
    12721 ttctaatgta atagttttaa ctttattagt ttctgtttta gatttagttt ttggtatgct
    12781 tacatattgc atagggtttt ctcgtatgtg tttgtaagga tggactgctg attttaatga
    12841 cctatgtaat atggctttta atacttgtaa tgtattttga gaataatcct ctttgtactt
    12901 tttatttatg aagttttgta gtattgcagg agttaaagct tttactttgt aagctcctag
    12961 ttttggcttt atatgttttt ctatgtttat tcggtagctt tcttgagtgt tgtatttaca
    13021 gttgagtaaa acatattctt tgtaccaaaa gtctaggtag tctgataagc tgatgttact
    13081 ttcttcaaag actatgccag agttttcata ttcatttagt gcttctctta gtgctttttc
    13141 tgcttctttt tttgtattgc caccaactct ttctactttt tttctttttc cttctactat
    13201 gcctaggtca aagtagtaat accatttgtt gcttcttttt cttactccac ctttcataat
    13261 agtatccctc ccttttagaa tgtatgtttg tttggtgttt atataaaaaa tgtctcctat
    13321 atttacaaga agacattaat tatattcgtc aaataatatt tctaatttaa cttttataca
    13381 ttcatcacaa ttattttctt tgttaacaaa tttaataatg caattatact ttaatcctct
    13441 atttattata cttgttaatt ctccactata atatctagga atgtaaccta tatgattctc
    13501 ttttttatca aataccttga ttgcatgagg atcaaattta ttttctggtt ctaactctag
    13561 aactagagct tcatttgatt ctaattctat tgaattatca cattcatgtc cttcacaccc
    13621 agcataatgt cttactcctg caatataaaa atatctaatt atatttttat caatgtccaa
    13681 aggaattgga tctacaaatt ctagtgtatc tataggtaat cttgcaccac ttctttttaa
    13741 aagttcatat gtatcatact cagacatatc atacttatcc aaaattttat tgatgtcctt
    13801 tcttttttta tcaggtaatc tacttgcaaa tgggctaaat aaatcttcac tataatatgt
    13861 tttactaata tcatcaaatg atattaaagc attaaaacct gctttaatag cttcatcaat
    13921 ttcatattca taagaaaatt catacaatcc atttttagct aactttccaa ttataaattg
    13981 tcttctactt tttggatctt tccaaataac atataaaaaa tcttttccat ttttaattga
    14041 cattttatcc ctctttcaca aattatatat attttttatt cttaacactt tttcttttag
    14101 atatattttt agcaattttt ttaactttgg gcttataata ttttctgaat agttatctat
    14161 taatgtattt atgtttactt cattcataag atttattatc ttttctacaa aatctatagt
    14221 ttgttcataa taatttgaat ttaaatattt tagcacttct aagtgtgttg gttctttttt
    14281 attttttcca tctatcctta ttcttgatct tgaacgtgta tttataagag cttcaaatct
    14341 ttgatgatca gtgaagaaag aatctatgtt ctcaatatta acataacaac ataatgatga
    14401 tccgttatca tatagaggac taagagtaat tttattttga ctttctagta gagcccaatt
    14461 attttgatgc ctatctctat ttccaatcaa gtaatcaaaa attaacattt ttagaaaatc
    14521 attttttatg ttatattctt ctatagattt aaaaatcatt ttcaatgaat agtattcatt
    14581 atttttataa tcatataact tatctgtatt ataacaagga taatatttgt ttattaacca
    14641 cacgccttca atcaatttct catcattttt attgattaaa taactcattg aaccaattct
    14701 tttattatat gtacctatct caacattagc acaaggaatc tttaacaaac tagctatttc
    14761 acaggctaat ttttctgccc aatattctcc agtttctttt gttttaggga atttaaacaa
    14821 gcctatatct ttagtttttt cattaattag ccagattttc tcgcttcttc cactaccata
    14881 agaaaaacca tcatactctt tccattcatc aaaattttta atcacgaaaa taatcctctc
    14941 aaacaagtat tttatattct tattgtatca tttgattcta aatttgcaag aattttatta
    15001 tccataataa gcttaactta aaataaaaat tttttctaga ttttatttat tccactttta
    15061 acttcaagct ttattacata tggaatatgt gtttactcat caaaattact actgtgtata
    15121 atggttttac tttataaata cttaatttta gttttctata tttatttggt aatttttttg
    15181 agtgttgtta agtaagaaat attttttgta ccaaaaggta agctgatatt gctttattca
    15241 gatactatgc ctaggtcaaa gtagtaatac catttgttgc ttctttttct tactccacct
    15301 ttcataatag tatctctccc ttttagaatg tatgtatgtt tggtgtttat ataaaagagc
    15361 agattaactg ctctttatat acttttgtta tgtacaatat tatcttaatt ttgtttatct
    15421 ggtttttact taattatttt cttaatattc ttacaatttt ttagctttta tgtgtagttt
    15481 attata
//
LOCUS       DAMJYN010000084        15486 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.088, whole genome shotgun sequence.
ACCESSION   DAMJYN010000084 DAMJYN010000000
VERSION     DAMJYN010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15486)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15486)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15486
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.088"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            55..390
                     /locus_tag="PC466_002951"
     CDS             55..390
                     /locus_tag="PC466_002951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2770315.1"
                     /translation="MYNIDDMIYNCPVEALSNILGKKWVAIIIWKIQEDKKRFGELQR
                     AIPDCSKKMLVQQLDFLIEQGIIVNQKKLVNNVVESTYFLSESGLRLLPVMEKMIMWS
                     NKNLNCDKY"
     gene            527..1804
                     /locus_tag="PC466_002952"
     CDS             527..1804
                     /locus_tag="PC466_002952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HDF2770316.1"
                     /translation="MQNVNLFLVFIEGIVSFFSPCILPILPIYLSILSNSSVENLKEG
                     KTSFIGSSLFKNTIFFALGISTTFFILGSSVKVLSMFFNENKDLIMFIGGIIIIIMGL
                     FYMGIIKSSILNREKRFNVKFKEMKAITAFILGFTFSFGWTPCIGPILASVLVMVSSS
                     SNHLSANLLIAVYTIGFILPFIITAMFYSKLFKTIDKIKSNMEIIKKIGGIILIVSGI
                     LMMVNGFGSISKHFNTSQNSKIESKQEENKRENSTDKEENSDGNNSQKDSNNDNNDNG
                     SNDEDRIKSIDFTLTDQYGKTHKLSDYEGKVVFLNFWATWCPPCKEEMPYIEQLYKDY
                     NKNNDDVVILGVASPNLGREGSREHVVNFLKDQGYTFPVVLDEDGALAYQYGINAFPT
                     TFIIDKEGYVTQYIPGAMDKATMASFIENQRNK"
     gene            1925..3313
                     /locus_tag="PC466_002953"
     CDS             1925..3313
                     /locus_tag="PC466_002953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDF2770317.1"
                     /translation="MKKTFDAIIIGFGKGGKTLAGDLANRGLKVALIEKSNKMYGGTC
                     VNVACIPTKSLENSANSVKTKNINSWDEVQAEYEKAIDKKETLITKLREANYNKLNSN
                     ENVTIFTGMGTFIDEKTVQVKTENEIYELVADNIFINTGSRPFIPNIKGIENKNIVYD
                     SESLMNLRVLPKKMTIIGAGFIGLEFAGIYSSFGAEVTILNSNNGILPNEDVEDSEEI
                     IKLLAKRNVKIVNNANIKEIKEVSESAIVEYEVDGKSKELTSNMILVATGRKANTEGL
                     GLENAGIELNERGFIKVSETLKTNKEHIWAIGDINGGPQFTYISLDDYRIVINQLFGD
                     KTRTTNDRKNIPNSIFISPAFSRVGLNVKQAKEKGYEVLVAKMPVEAIPRAKQIGKAD
                     GFIKIVIDKKSNKILGASMICENSSEIIHLIQLAVDLEVEYTYLRDRVYAHPTMTEAL
                     NDILSPNMIKEV"
     gene            3684..4397
                     /locus_tag="PC466_002954"
     CDS             3684..4397
                     /locus_tag="PC466_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017208807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF434 domain-containing protein"
                     /protein_id="HDF2770318.1"
                     /translation="MNKISKRGFDDSDKRWFSSKELTRLIKAKEEIEWLLNRDYKIDP
                     VVTFVGDRYQFSIRQRDALKRAVCTDEKNIIRQSKRLFLDKIKEDTVNIDGFNLIISI
                     EVALSGGTLVIGSDGNIRDLAGLRGTYKIIDKTEEALNLIGKFFNKYNAQNLKFYLDA
                     PVSNSGNLKYRILEHAKTWGIETEVELVKNADVVLEKLDRVVSSDAVIVDKCISYFNV
                     ARGIIEEYIKECNIINLNK"
     gene            4515..5384
                     /locus_tag="PC466_002955"
     CDS             4515..5384
                     /locus_tag="PC466_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HDF2770319.1"
                     /translation="MRGWICVKLTKLNIKKYRAPIYKYALANVNLRSAKSTNSSIITV
                     IPQGAKMEVLDEEDDWIKVMYNSQEGYVYKDLVSVSEYAWSNLNLREDKSITSNIITV
                     IPEKSRVEVLQVDGDWSKIVYDDKIGYVFNYFLSTDGNKPNELDYKYFYTDMIKFVNE
                     NNIKSTSDYLIVTDLRNKYTYIFKKDNGGWGQLYKWQCTIGKPETPTITGIFYISGRK
                     PSFGTDEYSVKYATRIKGGYYYHSVLYDSTGSYIIDGRLGEALSHGCIRLSTENAKWI
                     YDNIPDTTTVIIH"
     gene            complement(5539..6684)
                     /locus_tag="PC466_002956"
     CDS             complement(5539..6684)
                     /locus_tag="PC466_002956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HDF2770320.1"
                     /translation="MSTYYVPPINLLGKGCLNEAKDSIKSLGTKKAFVVSDKFLVSNG
                     TVKKVTDILSQIDVDFVVYDEVKQNPTVTNVDKGLKILKSENCDFVITIGGGSPQDCG
                     KAISILATNGGDIRDYEGINKTSKKCLPIVAITTTAGTSAEVTINYVITDEDRHVKMI
                     MVDTNSLATMTVNDPELMISKPSNLTAATGMDALTHAVEAVVANGAYDVTDSTALYAI
                     KQIFKYLPRAVKNGNDIEAREQMCYACFLNGIAFSNAGLGNVHAMAHQLGGLYDLPHG
                     VCNAMLLPIVEEENAKSAPAKFRPIAEVIGMDVNNKSDKECVDFVIDKIKALSEEVGI
                     PKSLKDVGVDNPNFELLAENSMKDACAGANPVFFDKEKIIELFMKIS"
     gene            complement(7017..7793)
                     /locus_tag="PC466_002957"
     CDS             complement(7017..7793)
                     /locus_tag="PC466_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HDF2770321.1"
                     /translation="MTSDNHRPTARILDILEALAESENGYTLTEIADVINAPKSSIFP
                     IVHTLNARKYITIDKNTSKYSIGIRSYTLGSSFFEKRTIFNYIIDEMTNIVNSCSETC
                     QLGILDNNEVLYIGKVDSPEPIRLISYVGKKIPANCTGLGKALLCDFDKEKLISLYPD
                     GLKGFTEKSITDFDVLYDQLLEVQRTQIASECEESMEHLKCLAVPIRKNGCIRAAVSV
                     TLPLFRANDEKIELIKKLLLNAQKNIQSMMEERNEDIVIN"
     gene            8375..9349
                     /locus_tag="PC466_002958"
     CDS             8375..9349
                     /locus_tag="PC466_002958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-3-deoxygluconate permease"
                     /protein_id="HDF2770322.1"
                     /translation="MIMDFIKKIPAGMMIVPMFIAAFINTFCPDIVQIGSFTTAVFSS
                     VGSATIIGVQLVCLGTQLQFREMPKVLKRGGILLGSKFAIGALIGILIGKLFGMDGVL
                     GLTTLAVISAVTNSNGSIYLSLMTSYGDETDCATMSLLTLNDGPFFTLIALGTSGLAN
                     VPLLSLLAAIVPILVGMIIGNFDKKMKEFLEPGCNLLVPFVGFALGSSINLASILKGG
                     LSGVLLGLISVFVGGIFIVFCDKFIGKRPGYAGWAVATTAGNAIAVPAAVALVDPSWQ
                     PYVATATTQVAAAVVVTAILVPLITSWWAKKYGCPKFPKQNEDGTITA"
     gene            9447..9752
                     /locus_tag="PC466_002959"
     CDS             9447..9752
                     /locus_tag="PC466_002959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HDF2770323.1"
                     /translation="MINAVIIDEKDNVAVAIEAIAKGNEISFKLKDKTVKTITALDNI
                     TIYHKLAIKDMAQGDKVTKYGEHIGEANQEIKSGQHVHIHNVRSVREDLDKQVMTNI"
     gene            9908..11068
                     /locus_tag="PC466_002960"
     CDS             9908..11068
                     /locus_tag="PC466_002960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HDF2770324.1"
                     /translation="MKFYGYKRPDGRVGIRNHILILPTSVCASDTTRIIASQVQGAVT
                     FNNQNGCSQVHSDQQLTMDVMAGYAANPNVYGVIVVSLGCENCQNDLVVDAIKERTNK
                     PIKTLVIQEEHGTLKTIEKAVRYAREMAQEASLLRKEEFPISELILGTECGGSDPTSG
                     LAANPLIGELSDKLVDLGATSILSETTEFIGAEHILARRAVNEEVKEKILHIVHRYEN
                     SLKLVGEEVREGNPSPGNIAGGLTSLEEKSLGCIHKGGHRQISEVYDYAKQIDKKGLV
                     IMDTPGNDASSVAGMVAGGAQIVVFSTGRGTPSGNPIAPVIKITGNKITFANMEDNMD
                     FDASPVIYGPQTMEELTDDLLNMVVDVANGKQSKAESLGYTEMAIARVCNYV"
     gene            11118..12020
                     /locus_tag="PC466_002961"
     CDS             11118..12020
                     /locus_tag="PC466_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="HDF2770325.1"
                     /translation="MKFVSFTEGENECKRTGVFSKDELFIIDVNSLNLSRNFKDLNEL
                     IQNVSSEDIIKLKTIINESIFYNYDVFKRERCTVHVPIEKPIHDILCVGVNYKDHLEE
                     TQTHFDDSFEEPQKTVYFTKRVTKAIGPEDEIDGHFEINNQLDYEVELGVVIGKTGVN
                     IRKEEVEDYIFGYTVINDISARKLQKEHVQWFRGKGLDTFTSLGPCILHKSAVPFPIK
                     LKVCSRVNGEERQSSNTGLFISDVSDIVSELSKGMTLEAGDIIATGTPSGVGMGFSPP
                     RYMSSGDVVECEIESIGILKNYIK"
     gene            12100..12993
                     /locus_tag="PC466_002962"
     CDS             12100..12993
                     /locus_tag="PC466_002962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HDF2770326.1"
                     /translation="MKAEFLTPVVTIFDEEGNLDKEGNKKVYDHLIDGGVDGLVIMGS
                     TGEFFNMSMDMQKELIDLVTSHVNKRVKVFIGTSRMCINESIELSNYAHNSGADGVMI
                     ISPYYFSLDDDSIELFYSEIAKNTEAEIYLYNYPDRTGYDLSPELTLRLARKHKNIVG
                     YKDTVTLMGHTRDLINTMKIEFPEFKVYSGYDENFIHNLMSGGAGCIGGLSNLIPEVC
                     SKWAEAYNNRDMEKVIEIQKYINKAMDFYLITNPFIPAMKKAMNIRGLQISDYMTAPF
                     VKPNEKQVCEIKKLMNKLNIC"
     regulatory      13046..13227
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            13455..14585
                     /locus_tag="PC466_002963"
     CDS             13455..14585
                     /locus_tag="PC466_002963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF2770327.1"
                     /translation="MKFKSNVLKQFFLIAMVIFMVGGLIGCSKSDKENKQASTGKKLE
                     LKYASGFSVEDLEDGIKKVTDGDNRELILIPKKIKIPEKYKNANIVRTPVDNVLIAST
                     TQACSLRTIDELDSIKAVTTEEQYWTIKEIKDLMKDGKIHYVGSNLAPDYEKIVDLNP
                     DLTIVSSGLSEADTKFIDKLKELGLNYVVDNEYKEQNPFGRMEWTSLIAAFYDKEDMA
                     TSELNKTVQKVEEVSKKIKNKAKPKVVWASVYEGSAYIAPKDSYVDNMIKMAGGINAC
                     ASIDSNEGRVSIEQLHEVAKDADIFVYSSSSDYAPNLDSIKSSAPVLADLDVVKNGNL
                     WVFAPDYYQSVDKTDELIVDLVEMFHPGTTGEKIKHYINYDK"
     gene            14657..>15486
                     /locus_tag="PC466_002964"
     CDS             14657..>15486
                     /locus_tag="PC466_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HDF2770328.1"
                     /translation="MDFINKMRIRNTTIFIVLIISMILTFLVCVAFGSVKIEFKEVID
                     VVLRGMDNTEHYKIIYNIRIPRVLATMVGGACLAVSGILLQIFFKNPIVEPYILGVSS
                     GSTLSVALMILGGYTLGFESVNSMSIFVAAFIGALIVMSIVILFANKVKNITTLLIIG
                     IMTGYVCSGITNVLQSFANSDKLKEFTMWSMGSFSGFTWEKVEILIIVGILGLLMTVF
                     IIKPLNAFLLGEEYAKSIGINIRFFRVLIVFISSILAAIVSAFAGPIGFIGLAVPQIS
                     "
BASE COUNT         5954 a         1719 c         2735 g         5078 t
ORIGIN      
        1 atattgctat aaaagtttgt ttaataaatt aaataaagaa aagaggagaa taaaatgtac
       61 aacatagatg atatgatata taattgtcca gtagaagctt tatcaaatat tttaggtaaa
      121 aaatgggtgg ctataattat atggaaaata caagaagata agaaacgatt tggagagcta
      181 caaagagcta taccagactg tagtaagaaa atgttagttc aacaactaga ttttttaatt
      241 gaacagggga ttatagtcaa ccaaaaaaag ttggttaata atgttgtaga gtcaacatat
      301 tttttaagtg aatcaggatt acgattgctt cctgtcatgg aaaaaatgat tatgtggagc
      361 aataaaaatt taaattgtga taaatactaa aatttactct gtaagtaatg aaaatttaat
      421 taagctatga gtagaaaaat gtattaaaat tacataattt tttagttaga ttttaattta
      481 gaaatgggat tgtaatattg gaaataaaat aaggaggaat tttaatttgc aaaatgtaaa
      541 tttattttta gtatttatag aaggtatagt atcattcttt tcaccatgta tactgccaat
      601 tttgcctatt tatttgagta tattgtcaaa tagtagtgta gaaaatctaa aagaaggaaa
      661 gacgagtttt ataggaagtt ctttatttaa aaatactata ttttttgctc ttggaatctc
      721 aacaacattc tttatattgg gttcatcagt aaaagtattg agtatgtttt ttaatgaaaa
      781 taaagattta ataatgttta ttggtgggat tataattatt atcatgggat tattttacat
      841 gggaataatt aaatcttcaa tattgaatag agaaaaaaga tttaatgtta agtttaaaga
      901 aatgaaagca ataacagctt ttatattagg ttttacgttt agttttggat ggacaccttg
      961 tattggtcca atattggcat ctgtattagt catggtttca agttcaagta atcatcttag
     1021 tgccaatctt ttaatagcag tatatactat tggttttatt ttgccattta taattacagc
     1081 tatgttttac agtaaactat ttaaaactat agataagata aaatctaaca tggaaattat
     1141 taaaaaaata ggtgggatta tacttatagt atcaggaata ttaatgatgg taaatggatt
     1201 tggaagtata agcaaacact ttaatacgtc acaaaatagc aaaattgaaa gcaagcaaga
     1261 agaaaataag cgagaaaatt ctactgataa agaagaaaat tctgatggta ataatagtca
     1321 aaaagactct aataatgaca ataatgataa cgggtctaat gatgaagata gaataaagtc
     1381 tattgatttt actttaacag accagtatgg taaaacacat aaattaagtg attatgaagg
     1441 caaagttgta ttcttaaatt tctgggctac atggtgtcct ccatgtaaag aagaaatgcc
     1501 ttatatagaa caactgtata aagactataa taaaaacaat gatgatgtag taattttagg
     1561 agtagcttca cctaatttag gtagagaagg ttcaagggaa catgtagtta acttcttaaa
     1621 agaccaaggt tatacattcc ctgttgtact tgatgaagat ggagcattag catatcaata
     1681 tggaattaat gcttttccaa ctacatttat aattgacaag gaaggatatg taactcagta
     1741 tattccagga gctatggata aggcaactat ggcatcattt attgaaaatc agagaaataa
     1801 ataaaagtat ttaagtatat gtttatgaat caatttaagg ttacaaaaaa gtgcctaatt
     1861 gtaccaccta aataatcttg ttatagtaaa agtataaaca atacaagaaa gggttgaatt
     1921 ttatatgaaa aaaacatttg atgctataat aataggattt ggaaaaggtg gaaaaacatt
     1981 agcaggagat ttggcaaaca ggggattaaa agtagcttta atagaaaagt caaacaagat
     2041 gtatggtggg acatgtgtaa atgtggcatg tataccaaca aaaagcttag aaaattcagc
     2101 aaacagcgta aaaacaaaga atataaattc ttgggatgaa gtacaagctg aatatgagaa
     2161 agctatagat aaaaaagaaa ctttaattac aaaactcaga gaagctaact ataataaatt
     2221 aaattcaaat gagaatgtaa ctatattcac aggaatggga actttcattg atgaaaaaac
     2281 agttcaagtt aaaactgaaa atgaaattta tgagttagta gcagataata tatttattaa
     2341 tactggttca agaccattta tacctaatat taagggaatt gaaaataaga atatagtata
     2401 tgatagtgag tctcttatga atctaagagt tttacctaaa aaaatgacaa ttataggagc
     2461 tggatttata ggtttagagt ttgctggtat ttatagttca tttggagcag aagttacaat
     2521 attaaactct aataatggca ttttaccaaa tgaagatgtt gaggattcag aagaaataat
     2581 aaaattactt gcaaagagaa atgtaaaaat tgttaataat gcaaatataa aagagattaa
     2641 agaagtttct gaatcagcaa tagtagaata tgaagtagat ggtaaatcta aagaattaac
     2701 aagtaatatg atacttgtag ctacaggaag aaaagcaaac actgaagggc tagggctaga
     2761 aaatgcaggt atagaattaa atgaaagagg atttattaaa gtctcagaaa ctcttaagac
     2821 taataaagag catatatggg ctataggaga tataaatgga ggtccacaat ttacttatat
     2881 atcattggat gattatcgca tagttattaa tcagttattt ggagataaga ctagaacaac
     2941 taatgataga aagaatatcc caaattctat atttataagt ccagcatttt caagagttgg
     3001 tcttaatgtt aaacaagcta aagaaaaggg atatgaagta ttagtggcaa agatgccagt
     3061 agaagcaatt ccaagagcta aacagattgg caaggcagat gggtttataa aaatagtgat
     3121 agataaaaaa tccaataaga tacttggagc tagtatgata tgtgaaaatt caagtgagat
     3181 tatccatctt attcaattag ctgtagattt agaagtagag tatacatatt taagagaccg
     3241 tgtttatgca catccaacta tgacagaagc tcttaatgat attctatctc ctaatatgat
     3301 aaaagaagta taacataagt ttaatatata aacctaaaat tatcattata agtagatttt
     3361 agaaagaggc tatctcaaaa aatagagata agtctctttt ttacttttta aatgataaaa
     3421 atatatttga ttttataaaa gaagattatc ttatgaacta aaaagtttat tttaaaacac
     3481 tacctattta tgttataaac ttataaatat aatatagaat ctattattct gtattattaa
     3541 gtgaggttaa gcgttataat taattataaa tattgaataa tctaaatgga taagataatg
     3601 gtattaaaaa ttatcttaaa aggtgaaata atctgtattt aatgtagtac agttatatct
     3661 ttaaagcaag gtggtgaaat gatataaata agatatctaa aagagggttt gatgatagtg
     3721 ataaaagatg gttttcaagt aaagaattaa caagacttat aaaggctaaa gaagaaatag
     3781 aatggttatt aaatagggat tacaaaatag acccagtcgt tacttttgtt ggtgatagat
     3841 atcagttttc tataagacaa agagatgcat taaaaagagc agtctgtact gatgaaaaaa
     3901 atattataag acaatcaaaa aggctttttc tagataaaat caaagaagat accgtaaata
     3961 tagatggctt taatttgata atatccatag aggtagcatt atctggtggt actctagtaa
     4021 taggaagtga tggaaatata agagatttag caggtcttag gggaacctat aagattatag
     4081 ataaaacaga agaagctttg aatctgatag gtaaattttt taataaatac aatgcacaga
     4141 atcttaaatt ttatttagat gctccagttt ctaattcagg aaatttaaag tataggatat
     4201 tagagcatgc caaaacttgg ggaattgaaa ctgaagtaga attagtaaaa aatgcagatg
     4261 ttgtattgga aaaattagat agagtagtta gtagtgatgc agtcatagtt gacaagtgta
     4321 taagttattt taatgtggct agaggtataa ttgaagagta tattaaagaa tgtaatatca
     4381 taaatttaaa taaatagata aatagaggtg agaatatata agtatatgta gcaatattat
     4441 tagtaataca agtaaagttt gaaaatagga gaacgaatac atatcgaatt tcataaaatg
     4501 ttgtaaaaag acatatgaga ggatggatat gtgtgaaatt aactaaacta aatattaaaa
     4561 aatatagagc acctatatat aaatatgctt tagcaaatgt aaatttgagg tctgctaaat
     4621 ctactaattc aagtatcata acagtaatac ctcagggagc taaaatggaa gtattggatg
     4681 aagaagatga ctggattaag gtgatgtaca attctcaaga aggatatgtg tataaggatt
     4741 tggtatcagt aagcgaatat gcttggagta acttaaactt aagagaagat aaatctataa
     4801 cttccaatat aattacagta attcctgaaa aatctagggt tgaagtcctt caagtagatg
     4861 gagattggag taagattgta tatgatgata aaataggata tgtttttaat tattttttat
     4921 caactgatgg gaataaacca aatgaattag attataagta tttttatact gacatgatta
     4981 aatttgttaa cgaaaataat attaaaagta ctagcgatta tctaattgta acagacctta
     5041 gaaataaata tacttatatt tttaagaaag ataatggagg ctgggggcaa ctttacaagt
     5101 ggcaatgtac tataggcaag cctgagactc caactataac aggtatattt tatataagtg
     5161 gaagaaaacc ttcttttgga acggatgagt attcagttaa gtatgctact agaattaaag
     5221 gtggatatta ctatcattct gtgctatatg attcaacagg aagttatata atagatggca
     5281 gacttggtga agctcttagt catggatgta taagattaag tacggaaaat gcaaagtgga
     5341 tatatgataa tataccagat acaacaacag ttataattca ttaagaaaaa ttttgagttt
     5401 ttattgggat aatgattctc aaattaatag gattatatat taacttcttc ataaagagta
     5461 ctatttaaaa agtgtaataa gagagtgcta ttaacaaaac aaagatattt tgaggcactc
     5521 tcttataaat atacataatt aagatatttt cataaacaat tctataatct tctccttatc
     5581 aaagaaaaca ggattagcac cagcacaagc atctttcata gagttttctg caagcaattc
     5641 aaaattagga ttatcaacac ctacatcttt taaagatttt gggattccaa cctcttcaga
     5701 aagagctttt atcttatcta ttacaaagtc aacacactct ttatctgatt tattatttac
     5761 atccattcca ataacttcag ctattggtcg gaatttggca ggggctgatt tagcattttc
     5821 ctcctcaact attggaagta gcatggcatt acatactcca tgaggtaaat catataaacc
     5881 tcctaattga tgagccatag catgtacatt tccaagacct gcattactaa aggcaattcc
     5941 atttaaaaaa caagcataac acatttgttc tctagcttct atgtcattac catttttaac
     6001 agctcttgga aggtatttaa atatctgctt tatagcatat aaggcagttg aatctgtaac
     6061 atcataagca ccattagcta ctacagcttc tacagcatga gttagtgcat ccataccagt
     6121 tgctgctgtt aaattagatg gtttgctaat cattaattct gggtcattta ctgtcattgt
     6181 agctagtgag ttggtatcaa ccattatcat ctttacatgt ctgtcttcat cagttataac
     6241 atagtttatt gtaacttcag cagatgtacc agcagtagta gttatagcta cgataggaag
     6301 acatttttta gaagttttgt tgataccttc atagtctcta atatctcctc cattagtagc
     6361 taatatagag atagctttac cacagtcttg tggagaacct cctcctatag ttataacgaa
     6421 gtcacaattt tctgatttta atattttaag tcctttatcc acattagtta cggttggatt
     6481 ttgtttaact tcatcataaa caacaaagtc tacatctatc tgagataaaa tatctgttac
     6541 tttttttaca gtaccatttg aaactagaaa tttatcacta acaacaaatg cttttttagt
     6601 tcctaatgat ttaattgaat ctttagcttc attaagacat cctttcccaa gtaaatttat
     6661 tggtggtaca taataagtgc tcataactaa aatctccttt tattttcatt gatttttatg
     6721 taaaaatata tatctaacaa ttttcactaa tttactcata atatatcgta tcttagattg
     6781 agatagggtt actggttctt atataagaac ttaattcgta attacgatta tgattagaat
     6841 ttaacatagt atttttatca tgtcaataaa aatataaaaa atattataaa aaaaacaaag
     6901 ttactgtagt taaatcagca actttgtttt tatagtataa atcaaataaa tacattagtt
     6961 taaaacaaaa tttttaatta ttatgttttg atatcttcca tatacagaat attaatctaa
     7021 tttattacaa tgtcttcatt acgttcttcc atcattgatt gaatattttt ctgagcattt
     7081 aagagtaatt tttttatcag ttctattttt tcgtcattag ctctaaataa aggcagtgtt
     7141 acactaacag cagctcttat acatccattt tttcttattg gtacggcaag acattttagg
     7201 tgttccattg attcttcaca ctctgaagct atttgtgttc tttgaacttc aagaagctgg
     7261 tcgtataaaa catcaaaatc tgtaattgat ttttctgtaa aaccttttag accatctgga
     7321 tataagctta ttagtttttc cttgtcaaaa tcacataaaa gagcttttcc aagacctgta
     7381 caattagcag gtattttttt tccaacataa gaaataagtc taattggttc tggagaatct
     7441 acttttccaa tataaagaac ttcattattg tcaagtatac caagctgaca agtttcagaa
     7501 caggaattaa ctatattagt catttcgtca attatatagt taaaaatagt tcttttttca
     7561 aaaaatgaag accctaatgt gtaagaacgt atccctatag aatatttgga tgtgttttta
     7621 tcaatagtaa tgtattttct agcattaagt gtatgaacta taggaaagat gctacttttt
     7681 ggagcattga taacatctgc tatttctgta agagtatatc cattttcgga ttctgctaat
     7741 gcttctaaaa tatctaatat cctagctgtt gggcgatgat tatctgaagt cataaatttc
     7801 cccctctttt tattaattta aagtattaga atatgttgat tttagcacac tatacgatat
     7861 tttacaatgt agaaaataaa tatgtaaatt tatatataaa taagctcttg atttagatac
     7921 agatagatat ttttttagac tgtacattaa ggaataacta atttccaaaa tatacctaaa
     7981 gaaagtaagt gatatttagt tatataattt aagtaaatat atgcaatagt tatttttata
     8041 tgtaaatatc aaaatattat gaatttatat tttatctatt ttttacactg tataaaaact
     8101 ttatagtttt gaatactata taattttaaa tacgctgtat ttttgcatat aaggaagtca
     8161 tttgataata tacaaggtat tatcagaaag tttgaaaaaa atttgacaaa aatttatttt
     8221 ttttattgac tcataaatag gaaaatgcta tcattaattc aaagattcgt aattaaaaac
     8281 ttagttctta aatacgaacc gaaacggccg ttagaattaa agctaaaaac ttaataagag
     8341 taattaaata tcatgtttta ggaggattaa ctttatgata atggatttta ttaaaaaaat
     8401 tcctgcaggt atgatgatag tgccaatgtt tatagcagct ttcattaata ccttttgccc
     8461 agatattgta caaataggtt cgtttacgac agcagtattt tcaagtgttg ggtctgcaac
     8521 tataattggg gttcaactgg tatgcttggg aactcagctt caatttagag aaatgccaaa
     8581 agttttaaag agaggtggta tacttcttgg ttctaaattt gctataggtg ctttgatagg
     8641 tatacttata ggaaagctat ttggaatgga tggtgtcctt ggtcttacaa cattggctgt
     8701 tataagtgca gttacaaata gtaatggtag tatatatctt tcattgatga cttcatatgg
     8761 agatgaaaca gattgtgcaa ctatgagttt acttacttta aatgatggac cattttttac
     8821 attaatagct cttgggactt caggtcttgc aaatgtgcca ttgttgtcat tattagctgc
     8881 aatagtgcca atacttgttg gtatgataat aggaaatttt gacaaaaaaa tgaaagagtt
     8941 tttagagcca gggtgtaatt tactcgtacc ttttgtaggg tttgcacttg gtagtagcat
     9001 aaatcttgca agtatactaa aaggaggttt atcaggagta ttacttggat taatatctgt
     9061 atttgtagga ggtatattta tagtattctg tgataaattt ataggaaaac gtccaggata
     9121 tgcaggatgg gctgtagcta caaccgctgg aaatgcaatt gctgtacctg ctgctgttgc
     9181 attagttgac ccatcatggc aaccatatgt tgcaacagct acaacacaag tggcagccgc
     9241 agtagttgtc actgcaatat tagtacctct tataactagt tggtgggcta agaagtatgg
     9301 atgtcctaag ttcccaaaac aaaatgagga tggtacaata acagcttaat ttatattaca
     9361 gtgagttgtt ggtaaaataa taaattcttt aattagattt taggatatta ataaaattat
     9421 attatttata aaggagagca agaataatga taaatgcagt gataattgat gaaaaagata
     9481 atgttgcagt agctattgaa gcaatagcta aaggtaatga aattagtttt aaattaaaag
     9541 acaaaacagt aaaaacgatt acagcactag ataatataac tatttatcat aaattggcta
     9601 taaaagatat ggcccaaggt gataaagtta ctaaatatgg tgaacatata ggagaagcaa
     9661 atcaggaaat aaaaagtggt caacatgtac atattcataa tgttagaagt gttagagagg
     9721 atttggataa acaagttatg actaatatat aaaataatat ttatagagtt ataaaagttg
     9781 tattcattgc ttttagtgtc aaatagtttt taaataggat tttagctgtt tgattagtga
     9841 gtgtaataaa aattataata tataaaaatt ataaaaagta tatagactat tttaggagga
     9901 aatcagtatg aaattttatg gatataaaag accagatgga agagttggta taagaaacca
     9961 catattaata ttgcctacga gtgtgtgtgc atcagataca actagaataa tagcatcaca
    10021 agttcaaggg gcagttacct ttaataatca gaatggatgt tcacaagtac attcagacca
    10081 acaattaact atggatgtta tggctggtta tgcagcaaat ccaaatgtat atggtgtaat
    10141 agttgtatct ttgggatgcg aaaattgcca aaatgatttg gtagttgatg caataaaaga
    10201 gagaacaaat aagccaataa aaactcttgt aatacaagaa gaacatggaa ctttaaaaac
    10261 tatagaaaaa gctgttcgtt atgctagaga aatggcacaa gaagcttctt tgcttagaaa
    10321 agaagaattt ccaatatctg aacttatact aggaactgaa tgtggtgggt ctgacccaac
    10381 aagtggatta gcagcaaatc cattaatagg tgaattaagt gataaacttg tcgatttagg
    10441 agcaacatca attttaagtg aaactactga atttataggt gcagagcata tactagctag
    10501 gagagcagta aatgaagaag taaaagaaaa aatattacat atagtacata gatatgaaaa
    10561 ttcattaaaa ttggttggag aagaagttag agaaggtaat ccatctcctg gaaatatagc
    10621 tggtggttta acaagtttag aagaaaaatc acttggttgt atacataaag gaggtcatag
    10681 acaaataagt gaagtatatg attatgccaa acaaattgat aagaaaggtc ttgttataat
    10741 ggatacccct ggaaatgatg cttcatctgt tgctggtatg gtagcaggag gagcacaaat
    10801 agtggtattt agtacaggaa gaggaacacc atcaggaaat ccaatagcac cagtaataaa
    10861 aataactgga aataaaataa cttttgcaaa tatggaagat aatatggatt ttgatgctag
    10921 tccagttatc tatggtccac aaacaatgga agaattaaca gatgatttgt taaatatggt
    10981 tgtagatgta gcaaatggaa aacaatcaaa agcagagtcc cttggatata ctgaaatggc
    11041 aatagctaga gtatgcaact atgtataatc tttaagtaag aaaataaata catagaattt
    11101 taataaaggg tgagattatg aagtttgtaa gttttactga aggagaaaat gaatgtaaaa
    11161 gaactggagt tttttctaaa gatgaattat ttattataga tgttaactct ttaaatctca
    11221 gtagaaattt taaggattta aatgaattaa ttcaaaatgt atctagtgaa gatattatta
    11281 agttgaaaac tattataaat gaaagtatat tctataatta tgatgttttt aaaagagaga
    11341 gatgtactgt acatgttcct atagaaaaac caatacatga tatcttatgt gtgggagtga
    11401 actataaaga ccatcttgaa gaaactcaaa ctcactttga tgatagtttt gaagagccac
    11461 aaaaaacggt ttattttaca aaacgtgtga caaaggcaat aggtccagaa gatgagatag
    11521 atggtcattt tgagataaat aatcaactag actatgaagt tgaacttgga gtagtaatag
    11581 gtaaaacagg tgttaatatt agaaaagaag aggtagaaga ttatatcttt ggttacactg
    11641 ttataaatga tatttctgct agaaagttgc aaaaagaaca tgttcaatgg tttagaggaa
    11701 aaggattaga tacatttacc tctttaggtc catgtatttt acataaaagt gcagttcctt
    11761 ttcccataaa acttaaagta tgtagtaggg taaatggtga agaaagacaa agttctaata
    11821 caggattatt catatcagat gtttcagaca tagtttcaga actttcaaaa ggtatgactt
    11881 tagaggctgg agacattata gctactggaa caccttctgg agtagggatg ggattttcac
    11941 ctcctcgata tatgagtagt ggagatgtag ttgaatgtga gattgagagt attggaattt
    12001 taaaaaatta cattaagtaa atgttttaat ataattaata ttaaagctaa atctgatgta
    12061 ttaatgaaca tattaaaata aattttagga gtttaaatta tgaaagcaga atttttgaca
    12121 ccagttgtta caatatttga tgaagaagga aatttagata aagaaggtaa taaaaaagtg
    12181 tacgaccatc ttatagatgg aggtgtagat ggactagtca taatgggaag tactggagag
    12241 ttctttaata tgtctatgga tatgcaaaaa gaacttatag atttagtaac tagtcatgta
    12301 aataagagag taaaagtgtt tataggtaca agtcgtatgt gtataaatga atctatagaa
    12361 ctttcaaact atgcacataa tagtggagca gatggcgtta tgataataag cccttattat
    12421 ttctctcttg atgatgatag tattgagtta ttttatagtg aaatagctaa gaatacagag
    12481 gctgaaatat atttatacaa ttatccagat agaactggtt atgatttaag tccagaactt
    12541 acattaagac ttgcaagaaa acataaaaac atagttggat ataaggatac agtaactttg
    12601 atgggacata ccagagattt aataaatact atgaaaatag agttcccaga atttaaggtt
    12661 tatagtggtt atgatgaaaa ctttatacat aatctaatgt ctgggggagc aggttgtata
    12721 gggggattat caaatttaat tccagaagtt tgctccaaat gggctgaagc ttacaataat
    12781 agagatatgg agaaggttat agaaattcaa aaatatatta ataaagcaat ggatttttac
    12841 ttaataacca atccatttat accagcaatg aaaaaagcta tgaatatcag agggttacaa
    12901 ataagtgatt atatgactgc tccatttgta aaaccaaatg aaaaacaagt atgtgaaatt
    12961 aaaaaattga tgaataaatt aaatatatgt taaatcaacc ttgcaaagag gtcaacaata
    13021 aattacaatt atcttaataa aaattaaatt aaaataatac tagggtacta tattagttta
    13081 atagggaaag tgatgaaaat tcactacagc ccccgctact gtatacggat acgaaatcaa
    13141 aatccactga aatttataaa aattttggga agggtgatgg aggaaaagcc gtgagtcagg
    13201 agacctgccc agtattatat aagttcaatt tagggtggag attgtaattt ataataaaat
    13261 gaagtatcaa ttcgtttttg taaagttgat atatgaactt ctccttatta aattaggaga
    13321 agttttttat tttattaaaa ggttatactt attaaagatg actttaggat aactttaata
    13381 agtatacttt aaaaagcata tattattaaa gttttttagc cactcataaa aaataagata
    13441 ttggagtgaa agagatgaaa tttaaatcaa atgttttaaa gcagtttttt ttaattgcta
    13501 tggtaatttt tatggtagga ggtcttatag ggtgtagtaa aagtgacaaa gagaataaac
    13561 aagctagtac tggtaagaaa ttagaattaa aatatgctag tggatttagt gttgaagatt
    13621 tagaagatgg aattaaaaaa gtaactgatg gagataatcg agaactgatt ttaatcccaa
    13681 agaagattaa aattcctgaa aaatataaaa atgctaatat agttagaacg cctgtggaca
    13741 atgtattaat agcatctaca acacaggctt gttctctgag aacaatagat gaactagata
    13801 gtataaaagc cgtaacaaca gaagagcagt actggactat taaagaaatt aaagatttaa
    13861 tgaaagatgg aaaaatacat tacgttggtt caaatttagc accagattat gaaaaaatag
    13921 tagacttaaa tcctgactta actatagtga gtagtggttt atcagaggct gatacaaaat
    13981 ttattgacaa attaaaagaa ttagggctta attatgttgt agacaatgag tataaagagc
    14041 aaaatccatt tggaagaatg gagtggacaa gtttaatagc tgcattttat gataaagaag
    14101 atatggctac tagtgaacta aataaaactg tacaaaaggt agaagaagta agtaaaaaaa
    14161 taaaaaacaa agctaaacct aaagttgtat gggcatctgt atatgaagga agtgcttata
    14221 tagctcctaa agattcatat gtggataata tgataaaaat ggctggtgga ataaatgcat
    14281 gtgcttcaat agattcaaat gaagggcgag taagtattga acaattgcat gaagttgcaa
    14341 aagatgcaga tatatttgta tactcatcaa gttcagatta tgcaccaaat ttagattcta
    14401 taaaatctag tgcacctgta ttggctgatt tggatgttgt aaaaaacgga aacctatggg
    14461 tgtttgctcc agattattat caatcagtag ataagacgga cgaattaata gtagatttag
    14521 ttgagatgtt ccacccaggt actacaggtg aaaaaatcaa acattatata aattatgata
    14581 aatagtacag agaggacaca aaaagatagg ttttatagat tttagttaat ataactttgc
    14641 taagaggagt atacaaatgg attttatcaa taaaatgaga ataaggaata cgacaatatt
    14701 tatagtatta attataagta tgatacttac ttttttagtg tgtgtagcat ttggctctgt
    14761 aaaaattgaa tttaaagaag taatagatgt tgtattaaga ggtatggata atacagaaca
    14821 ttataaaata atatacaata taagaatccc tagagtactt gcaaccatgg taggtggagc
    14881 atgcctagca gtatcaggta ttttattaca gatatttttt aaaaacccaa tagttgaacc
    14941 gtatatatta ggagtatctt caggttctac tttatcagta gctctcatga ttttgggagg
    15001 atacacattg ggatttgaga gtgtaaattc aatgagtata tttgtagcag cttttatagg
    15061 agctttaatt gtaatgtcta tagtcatttt atttgcaaat aaggtaaaga atataacaac
    15121 tcttttaata ataggaatta tgaccggata tgtatgtagt ggtataacaa atgtgttaca
    15181 atcatttgca aatagtgata aattaaaaga atttactatg tggtctatgg gaagtttttc
    15241 tggatttaca tgggaaaagg tagaaatact tataatagtt ggtatattag gtcttttgat
    15301 gactgtattc ataataaaac ctttaaatgc ttttttatta ggagaagagt atgcaaaaag
    15361 tattggcata aatataagat tttttagagt tttgatagtg tttatatcta gtatattagc
    15421 agcaatagta tcagcatttg caggacctat agggtttatt ggacttgcag tgccacaaat
    15481 ttcaaa
//
LOCUS       DAMJYN010000085        15467 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.089, whole genome shotgun sequence.
ACCESSION   DAMJYN010000085 DAMJYN010000000
VERSION     DAMJYN010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15467)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15467)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15467
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.089"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            93..1484
                     /locus_tag="PC466_002965"
     CDS             93..1484
                     /locus_tag="PC466_002965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HDF2770329.1"
                     /translation="MSSTESVSKKSGHPKSFWLICMTILWERFSYYGLTALLVLFFTA
                     SVAQGGLGLSTQEATSMFGLFTGLIYLTPLVGGWLADKVLGQQKCISIGALLIAIGDF
                     VLFASSTSIAMVWVGLSIIILGNGFFKSSCSNIVGDIYPKTDVSRKDAAYSLFYMAVN
                     VGAFIAPIICGLLSDNVFAVRGASGDIVSYGYKMAFLICGIGMMLGMIIFTLLAPKLL
                     NEVGKYPVTKGNKGEKIEYGPLTKLEKNRIIAMVILFLFVVLFWTAYYQTQSSFMIYV
                     RDNVNRTLFGFEMPVAWLTSLNAILCVALCPVLATLWVKLSHTKRGDFSIPVKMGLGM
                     IIMGVGFIVMVFATLANGPDGMVKASILFIVLTYIFTTVGELFLSPIGLAMFNKLAPA
                     KYATLSMGAWYLTSFFASLLSGKIAGFTATLGFLQIFGGIATVLIIFGLILLGIRNVL
                     TRLMAMDLLTKEK"
     gene            1737..3530
                     /locus_tag="PC466_002966"
     CDS             1737..3530
                     /locus_tag="PC466_002966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HDF2770330.1"
                     /translation="MNIKDRLSGLRKFMEEKNIDAYMIPSSDNHQSEYVGDYFKSREF
                     ISGFNGSAGTVIVTKDEAGLWTDGRYFIQAESQLEGSTIKLFKMGQEGCPTTDEYLYK
                     NIPEGGTLGFDGRVISAREGATLAEKLSKKGIKIEYQYDLIDGIWPDRPALSDSKAFL
                     LDVKYCGESFSSKLARLREKMSEKGTSTHVITTLDDIAWLFNIRGGDVKYNPVVLSYA
                     VITLKEVYLFVDESKLNEEILDELAKENVQIKPYNDVYEFVKNIDKTEKVLLDGTKLS
                     YTIYNNIPCEVEKVDEFNPVMFFKAQKNEVELENIRNSHVKDGVAFTKFMYWLKKNVG
                     KMEITEISATQKLEDLRREQEGFFEPSFNTIAAYKEHAAMMHYSATPESNYKLEAEGL
                     FLVDSGGQYYDGTTDITRTTVLGPISDELKLHFTSVARGMINLSKAKFLHGCRGYNLD
                     ILSRSCMWNMGIDYQCGTGHGIGFVLNVHEAPNGFRWRVVPERFDSAVLEEGMVTTNE
                     PGIYIEGSHGIRTENEIVVRKAEKNFYGQFMEFEVVTLAPIDLDGIVPELMNKDEKDY
                     LNWYHKLVYDKISPFLTDEEREWLKVYTRAI"
     gene            complement(3611..4993)
                     /locus_tag="PC466_002967"
     CDS             complement(3611..4993)
                     /locus_tag="PC466_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HDF2770331.1"
                     /translation="MSVLKTQEKLKQPRDLYFCCSIFTFVGLAYYGMKLVLLLFLAEQ
                     VSKGGLGLTPAESASMLASFLAWTYFSPVIGGWVSDRFLGPKNCIILGMLMVSIGYFL
                     GYIANSKMDINIMIFLSGLGIGFYKGNLHTMVGNLYTNDDPRKDGAFSITYMATNLGT
                     LFGPLICGLVANEWFAMKSGLSISMYGYRYVFLFSSITVLIGLFFFIFGNRKFYKPLN
                     NDPSNGRESIRKSLEYKKMLASRPLTLIEKKRIIVILVLAFFTVFFWIAYNQASMSIA
                     LYTKEHINLTVGNFQIPTSWIDSYNGLLCVILGPISALVWVKLSQTKKGDLSVPKKMS
                     LGFILLAIAFLFMIVAVIQTGTDPNSIHKASVFWVVGFLTFQSIGEICFSPVGYGMVN
                     KLSPEKYISFLMGVWFLGKFAANKLSGYTQAIIDQLGMLQVFIVIPSFLLIFGIILLI
                     MNKKLVELSN"
     gene            5251..5598
                     /locus_tag="PC466_002968"
     CDS             5251..5598
                     /locus_tag="PC466_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HDF2770332.1"
                     /translation="MIRKKSELQVEVKENLNGGIGKVKLENIIQNEELKGKGRLFKRV
                     ALPVGSSIGVHDHTTDFEVYYILKGKGKVFDNGEFVEVNEGDVVYTADGEKHSIENIG
                     EEDLEFVALVLYM"
     gene            5616..6650
                     /locus_tag="PC466_002969"
     CDS             5616..6650
                     /locus_tag="PC466_002969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770333.1"
                     /translation="MTGKIEEIKDKINRFCNSNLNQEYKDISFKILQNLLDNNKEIIH
                     SSRADIWSSAILNIVLEQNLLYNKKHPLHITKKEFSKQIGVSLNTINNKSSLIKDVCS
                     IDFLNQDTIAISNVEFWVKETNSKSKSVDLDLEKKKILYKRYIKLSQDANSDIESIRY
                     MEEAVNIGKSMITKEDKELGFWKGLSTRAYMIALESLARKLESINNLKESKKVLEYLI
                     EINPSDEQGIRYKLLNVLIRLNDRTSINKLFELYKEEKSATWMYSKALYYFKNKSMFL
                     ANDSIKVARSKNKYVGLYLLDWRNAFGREFVTEEEKAEAVYYYDENIVVWNEVKGSMD
                     WLLKKMLEFS"
     gene            complement(6699..7748)
                     /locus_tag="PC466_002970"
     CDS             complement(6699..7748)
                     /locus_tag="PC466_002970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF2770334.1"
                     /translation="MEINYKKRNFKSFAKRKNIEISVQRYLIDALSYMALGLFSSLLI
                     GTIFNTLGDNFNISLFTEVISPLAKQVTGPAIAVAIAYGLQAPPLVLFSCALVGACGN
                     ELGGPVGAFVATLFAVEVGKLVSKETKIDILVTPAVTILIGVLVAELIGPAVSAFMTS
                     FGNIIMQATTMQPIIMGALVSALVGIALTLPISSAAICMMLSLGGLAGGAATVGCCCQ
                     MVGFAVMSFRENRVGGLVAQGLGTSMLQVPNIIKNWKIWIPPTVASILLGPLSTTIFK
                     MENIPIGSGMGTCGLVGQFGTVTAMQSAGKGGISMWVGILLLNFILPAIVTLLISEFM
                     RKKGLIKPEDLKLDV"
     gene            8023..9558
                     /locus_tag="PC466_002971"
     CDS             8023..9558
                     /locus_tag="PC466_002971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770335.1"
                     /translation="MIFVKNKKYRKIAIIISIPILLVAQYYLFKFGILRPMVKGVEIE
                     IVDGEYVKDIDKYVVKLNETVTLSTGEYIKVPSYAKNPNIWFNVLDNSGTLKIDGNKM
                     TALKVGYSSVGIMKNSRVLKKATIKVVDPEVESLDMEINGDLKHVGDSATIESTIEVD
                     YDKFKKSYKPVYKSSNENILKIKGNKVSAVGVGKATIYAKCGNKEIERTFRIQARVAE
                     INMDDIKIEVDQNEKLKPDIITSPPGLEPPKIYYELVDSKLPVERAISLSSNGNVVGL
                     REGKDRVRITCGDKSKVITVTVVKETITNDYIQNLVGSHKIVNNKVIIKLEWDYMKDV
                     FDYDIYLKDKLSGESFKKIKSITINESDLGKSNKVYATIEVDMKGNQNIDFDIYVIGK
                     KDSDTTKPSNVINITNGNGNSNNDNNIKDMRVENISANVDRDNNVIRVNWSSISHKDC
                     TYSIYVKNNTNGDGEFNLYQSDIQGNEHTISIPEGDLNLDIYVVANYNGNSSQNSDVI
                     NVR"
     gene            complement(9744..10430)
                     /locus_tag="PC466_002972"
     CDS             complement(9744..10430)
                     /locus_tag="PC466_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate/glutamate racemase family protein"
                     /protein_id="HDF2770336.1"
                     /translation="MKTIGLIGGMSWESTITYYQVINTVIKERLGGLHSSKCILYSVD
                     FQEIEECQSSGNWEKSAKILADAAIKLQEAGADFIVICTNTMHKVSDKIQESIHIPLL
                     HIADVTATVLREKEIKKVALLGTKYTMEQDFYKNVIINNGIEVLIPNEEDRIIVNDTI
                     FNELCLGIISESSKKAFLSIIDKLGKQGAEGVILGCTEIGLLIKQNDTSIPLFDTTVI
                     HAIEAALSSI"
     gene            10555..11937
                     /locus_tag="PC466_002973"
     CDS             10555..11937
                     /locus_tag="PC466_002973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HDF2770337.1"
                     /translation="MPINSFENYPMTWKPKLDNRKPPIYKTLAMLLEEDIKRGNLNPG
                     DKLPPQRELADFLDLNLSTITRAFKLCEEKGLICAKVGKGTFISSDVNVSNTLLYQTE
                     SKDIIELGTVHPPYEQNTYIIDFIKNVLKQPEMDRFLQYMSPSGTYMQKKSIAKWIER
                     NNVYTSEENILLSTGGQNAICATLLGLFKAGDRIATDSLSFSGIKSIAKMIGIQLVPI
                     PQENNEISIEYLESYCKNENIKGIYLIPDYHNPTTHTMSDLSRKKIAKIAKQYNIIII
                     EDAINSIFRDGIQTPIFSLASDNTIYIFSTSKFLCAGLRVAFVVAPKRYIENLENALY
                     NMNLMVSPFTAEIVHRLLYSPIIDKIIEEKRDAIIERNEVADKVLSDYNLIGDKNCSF
                     RWLLLPDELDGKSFEISAKNLGVQVYCAERFSVGNSTVPKAVRICVTAPKDVEELEKG
                     LNIIKSLLKS"
     gene            12339..13607
                     /gene="eam"
                     /locus_tag="PC466_002974"
     CDS             12339..13607
                     /gene="eam"
                     /locus_tag="PC466_002974"
                     /EC_number="5.4.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 2,3-aminomutase"
                     /protein_id="HDF2770338.1"
                     /translation="MNEQTRISLERAAELKSKIDDYIQARKTINRGLEKEEEINKRKQ
                     KILSILNGTEEDWNNYKWQLSNRITDVDTLSKIITLTKKEKEYIKEVGTQFRWAISPY
                     YLSLIDPEDICDPIKLLSIPTHIELEDEQEDLDPMGEEYTNPAGCITRRYPDRLIINV
                     TNECAMYCRHCQRRRNIGQQDSHKSKAIIQESIDYIRENEEIRDVLVTGGDALTLKDD
                     YLEWILSQLKEIPHVDYVRLGTRTLVTMPQRITDEFCNMLKKYHPVYINTHFNHPMEI
                     TKESKEACEKLANAGVPLGNQAVLLNGINNDKFVMRCLNQELLKIRVKPYYIFQSKHV
                     KGTKHFNTSVDDGLEIMEYLRGYTSGMAIPTYIVNAPKGGGKTPLLPQYLVSKGTDYV
                     MLRTWEGKVIKMEDEPAVDIKKLIKEQAQD"
     gene            complement(13700..14056)
                     /locus_tag="PC466_002975"
     CDS             complement(13700..14056)
                     /locus_tag="PC466_002975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770339.1"
                     /translation="MKKALISLLVLSCLLLTAPVNESSYADSQKNVPVSQNTKLTQEQ
                     AKELLVKYNNEVDYIYQGNASDFEALKAKNLNGYVFLPDADGDIGYFVNENTSEIYYF
                     HPSGYLELVNQQQNNK"
     gene            complement(14207..15301)
                     /locus_tag="PC466_002976"
     CDS             complement(14207..15301)
                     /locus_tag="PC466_002976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HDF2770340.1"
                     /translation="MQDKKIYLNIVLTVVVSYILIKVIDNYKYFFGVISLLMSLLTPF
                     IIAFVLAYIFNPLVKFLESKLNFKRIYSLLLTYGVLIVILISFILFTVPSIVNSLADL
                     VAQIPTYIDKTEQFLFDLGKSLQSVDPNTLKEYGDKIMSVMPKFSNLLIGSLGGIFST
                     TFSVGKFIVQFLLGFIICFYILLEKEKFLLFTKKVVYISLGKKYGDFIIELCQSLNLN
                     IGKYFTGKILDSFIVGVLSGIGLYFLKSEYALLFGTLMGVMNMVPYFGPVIGMAPVVI
                     INLFSNPTIALTSLIYLIIIQQVEVTFIEPKIVGGQLGLSPFFTILAVTVGGGFFGIP
                     GMILSAPVMGVIKIYFCEFVNRRHDKIQME"
BASE COUNT         5987 a         1914 c         2490 g         5076 t
ORIGIN      
        1 catagaaaag atgatattat aagtatgtgc taaaatggtt aaagcaatat taatattaaa
       61 ttcaactata aaacaaaagg gggcgttttt ttatgtcaag tacagaaagc gtatctaaaa
      121 aaagtggtca tccgaagagt ttttggctta tttgcatgac aattttgtgg gaaagattta
      181 gttattatgg tttaacagct ttattggtat tattttttac agcaagtgta gctcaaggtg
      241 gtttaggtct ttctactcaa gaagcaacat ccatgtttgg cttatttaca ggtcttatat
      301 atcttacacc attagtcggt ggctggttag cagataaagt tttaggtcaa caaaaatgta
      361 tttctatagg tgcactttta atagcaatag gagatttcgt actatttgct tcatctacat
      421 ctattgccat ggtttgggta ggtctatcaa taattatttt aggaaatggt ttttttaaat
      481 caagttgttc aaatatagtt ggggatatat atcctaaaac tgatgtgtca agaaaagatg
      541 cagcatacag tttattctat atggcagtaa atgtaggagc atttatagct ccaataatat
      601 gtggattgct ttctgataat gtatttgcag taagaggagc aagtggagat atagtatctt
      661 atggatataa gatggcattt ttaatttgtg gtataggcat gatgttaggt atgattatat
      721 ttacacttct tgcaccaaaa ttattaaatg aagtcggaaa atatcctgtg actaaaggta
      781 ataaaggtga aaaaattgag tatggaccac ttactaagtt ggagaaaaat aggataatag
      841 caatggttat tttattttta tttgtggtct tattctggac agcatactat caaacacaaa
      901 gttcttttat gatttatgta agggataatg taaatagaac tctatttgga tttgaaatgc
      961 cagtagcatg gcttacatca ctaaatgcta tattatgtgt ggctttatgc ccagtattag
     1021 ctaccctatg ggttaaatta tctcatacca aaagaggtga tttctctatt ccagttaaaa
     1081 tgggattagg aatgataata atgggtgttg ggtttatagt tatggtattt gctacattag
     1141 ctaatggtcc agatggaatg gtaaaggcta gtatattgtt tatagtattg acttatatat
     1201 ttacaacagt aggtgaatta ttcttatctc ctataggact tgcaatgttc aataaattag
     1261 ctccagctaa gtatgctaca ttatctatgg gagcctggta tctaacaagt ttttttgcaa
     1321 gtttattatc aggaaagatt gctggtttta cagccacact tggtttttta cagatatttg
     1381 gaggaatagc aacagtttta ataatatttg gtttaatatt attgggaata agaaatgtat
     1441 taacaagatt aatggctatg gatttactaa caaaagaaaa ataattcatg acgaattatt
     1501 gtaaatagat gaattacttc aaataaagga agttacattt aaatataaaa ttaaatgtaa
     1561 tttcctcttt gattatgaaa aaaagcttta cacaaataga tattataatt aaaattataa
     1621 ttgtgataat tagagtgtat aagatttata taaattatac aaaaaatatt tatgtaataa
     1681 actttacata cttatatatt tagttattca aactattatt tcgaggaggt cttgttgtga
     1741 atataaaaga tagattaagt ggattaagaa aatttatgga agaaaaaaat atagatgcct
     1801 atatgattcc atcttctgat aatcaccaaa gtgaatatgt aggagattac ttcaaatcaa
     1861 gagaatttat atcagggttt aatggttcag cagggacggt tattgtgact aaagacgaag
     1921 ctgggttatg gaccgatgga agatatttta tacaggcaga atctcaatta gaaggaagta
     1981 caataaaatt attcaaaatg ggacaagaag gttgcccaac tacagatgaa tatttatata
     2041 aaaatattcc tgaaggagga actttaggat ttgatggtag agttatatct gctagagaag
     2101 gagctacatt agctgaaaaa ttatctaaaa aaggtataaa gatagaatat cagtatgatt
     2161 taatagatgg tatatggcca gatagacctg ctttatcaga tagtaaagca tttttattag
     2221 atgttaaata ttgtggagaa agttttagct caaaattagc tagattaaga gaaaaaatga
     2281 gtgaaaaagg tacttctact catgtaataa ctactcttga tgatatagca tggttattca
     2341 atataagagg tggagatgtt aaatataatc cagttgtact ttcttatgca gtaataactt
     2401 taaaagaagt ttatttattt gttgatgaaa gtaagttaaa tgaagaaata ttagatgaac
     2461 tagctaagga aaatgttcaa ataaagccat ataatgatgt gtatgaattt gtaaaaaata
     2521 tagacaaaac tgaaaaagtt ttattagatg gaactaagct tagttataca atttacaata
     2581 atataccttg tgaagttgag aaagttgatg agttcaatcc agtaatgttt tttaaagctc
     2641 aaaaaaatga ggtagaatta gaaaatataa gaaattcaca tgtaaaagat ggtgtggctt
     2701 tcactaaatt tatgtactgg ttaaagaaaa atgtaggtaa gatggaaatc actgaaataa
     2761 gtgctactca aaaattagag gacttaagaa gagagcaaga aggtttcttt gagccaagtt
     2821 tcaatacaat tgctgcatat aaagagcatg ctgcaatgat gcactatagt gcaactccag
     2881 agtcaaatta taaattagag gcagaaggat tatttttagt agattcaggt ggacaatatt
     2941 atgatggaac tactgatata actaggacta cagttttagg acctataagt gatgaattaa
     3001 aactacactt tacttctgta gcaagaggaa tgataaatct ttctaaggct aagttcttgc
     3061 atggttgtag aggatataac ttagacatac tatctagaag ttgcatgtgg aatatgggaa
     3121 ttgattatca atgtggaact ggacatggta taggatttgt gctaaatgtt cacgaagctc
     3181 caaatggatt tagatggaga gtagtacctg aaagatttga tagtgcagtt cttgaagaag
     3241 gaatggtaac tactaatgaa ccaggtatat atatagaagg ttctcatggt ataagaacag
     3301 agaatgaaat tgtagttaga aaagctgaaa agaatttcta tggtcaattt atggaatttg
     3361 aagttgttac gttagctcct attgacttag atggtatagt accagaatta atgaataagg
     3421 atgaaaaaga ttatttaaac tggtatcata agttagttta tgataaaata tcacctttct
     3481 taactgatga agaaagagaa tggttaaaag tttacactag agctatatag tttgtactag
     3541 atacaataaa aatcgaggta ttataatgcc tcgatttttt attgtatatt ttattaactt
     3601 taaaaaattt ttaatttgat aattctacta attttttatt cattataagt agtataattc
     3661 caaatatcaa taaaaatgat ggtatcacta tgaagacttg taacatacca agttggtcta
     3721 taatagcttg cgtatagcca gataatttat ttgctgcaaa tttgcctaaa aaccaaacac
     3781 ccattaggaa tgaaatatac ttttcaggcg aaagtttatt taccatacca tacccgactg
     3841 gagaaaagca aatttctcct atactttgga atgttaaaaa tccaactacc caaaatacac
     3901 ttgctttgtg aattgaatta gggtctgttc ctgtttgtat aactgctact atcataaaca
     3961 aaaatgctat agctaatagt ataaaaccta agctcatttt ttttggcaca cttaaatcgc
     4021 cttttttagt ttgagataat tttacccata ctaaagcaga gataggtcca agaataacac
     4081 aaaggagacc attgtatgaa tctatccatg aagtaggaat ttgaaaattg ccaacagtaa
     4141 gatttatgtg ttcctttgta tagagtgcaa tagacataga ggcttggtta tatgctatcc
     4201 aaaaaaatac tgtgaaaaaa gctaacacca atattactat tattcttttt ttctcaatca
     4261 aagttaaagg tcttgaagcg agcattttct tatattctag tgattttctt atagactctc
     4321 tcccgttact agggtcatta ttcaaaggtt tataaaactt tctgtttcca aatataaaga
     4381 agaataaacc tattagaacc gtaattgatg aaaataaaaa tacatatcta tatccataca
     4441 tacttataga taatccgctt ttcatagcaa accattcatt agcaactaaa ccgcatatta
     4501 aagggccaaa taaagtacct agattagtag ccatatacgt aatagagaaa gctccatctt
     4561 ttcttgggtc atcattggta tataagtttc caaccatagt atgtaagttt cctttataaa
     4621 aacctattcc taatccagat aaaaatatca tgatgtttat atccatctta ctatttgcta
     4681 tgtatcctag aaaataacca attgaaacca ttagcattcc aagtataata cagtttttgg
     4741 gacctaaaaa tctatcactg acccatccac caataactgg agagaaataa gtccatgcta
     4801 aaaaagatgc aagcattgat gcggattctg ctggtgttaa ccctaaacca cctttggaga
     4861 cttgttcagc taaaaacaat aataatacca atttcatacc atagtatgca agtcctacaa
     4921 aggtaaatat tgaacagcag aaatataaat ctctaggttg tttaagtttt tcttgcgttt
     4981 ttaaaactga catatgtcga gaacctccag ataaatagtt taacaaaatt ttaccatact
     5041 atatgagtat atgttttttt catatagacg tcaacttgta agataattta attaagtcga
     5101 aatatatgta aaaatagtat catttttgtg tattcagtaa tattttttta tgataatata
     5161 tgttattatt atattaaaat acaaacatat ttatggaaag gatatgccaa tttagtagtt
     5221 agattgattg tttggcaggt gggatgagct atgataagaa agaaatctga attacaagta
     5281 gaagtaaaag aaaatttaaa tggtggtata ggaaaggtta agcttgaaaa cataatacaa
     5341 aatgaagagc ttaaaggaaa aggaagacta tttaaaagag tagctttacc agtaggaagt
     5401 tcaattggtg tgcatgacca tacaacagat tttgaagtat attatatact aaagggaaaa
     5461 ggtaaagtat ttgataatgg ggaatttgta gaagtaaatg agggtgatgt agtgtataca
     5521 gctgatggcg aaaaacattc tatagaaaat ataggagaag aagatcttga gtttgtagca
     5581 ctagttttat atatgtaaaa tatggaggag gagtcatgac aggcaagata gaagaaatta
     5641 aggacaagat aaatagattt tgcaactcca atttaaatca agaatacaaa gatataagct
     5701 ttaaaatttt gcaaaacctt ttagataata ataaagagat aattcattct tctagagctg
     5761 atatatggtc ttcagctata ctaaatatag ttttagaaca aaatctttta tacaataaga
     5821 agcatccact acatataaca aaaaaagagt tttcaaaaca aataggtgtt tctttaaata
     5881 ctataaataa taaatcgtct ttaataaaag atgtttgtag tattgacttt ttaaatcaag
     5941 atactatagc tatttctaat gtagaatttt gggtaaaaga gaccaattcc aaatcaaagt
     6001 ctgtagattt agatttagaa aagaaaaaaa tactatataa aagatatatt aagctatcac
     6061 aagatgcgaa tagtgatatt gaatcaatta gatatatgga ggaagctgta aatataggta
     6121 aaagtatgat tactaaagaa gataaagaac ttggattttg gaaaggttta tctaccagag
     6181 cctatatgat agcacttgaa tcccttgcta gaaagttaga aagtattaat aatctaaagg
     6241 agtccaaaaa agtattagaa tatttaatag aaattaatcc tagtgatgag cagggaataa
     6301 gatacaaatt attaaatgta ttaattagat taaatgatag aacttcaata aataaattat
     6361 ttgaacttta taaagaagaa aaatctgcta catggatgta cagtaaagct ctttattact
     6421 ttaaaaataa aagtatgttt ttggcaaatg attctattaa ggttgctaga agtaaaaata
     6481 agtacgttgg attatatttg ttagattggc gaaatgcttt tggtagagaa tttgttacag
     6541 aggaagaaaa ggcagaagct gtctattact atgatgaaaa catagtggtt tggaatgaag
     6601 ttaaaggttc tatggattgg ctattaaaaa aaatgttgga attttcataa aaaaaactac
     6661 tccttacttt tatataagta aaaggagtag tttttaattt atacatctag ttttaaatct
     6721 tcaggtttta ttagaccttt ttttctcata aattctgaaa tcaacaaagt tacaatagca
     6781 ggaagtataa aattaagtaa aagtatacca acccacatag atatacctcc ttttccagca
     6841 ctttgcatag cagttactgt tccaaattgt ccaaccaatc cacaagtacc cataccagaa
     6901 ccaataggaa tattctccat tttgaatatt gttgtagata atggtccaag taatattgaa
     6961 gctacagtag gtggtatcca aattttccaa ttttttatta tattaggtac ttgcaacata
     7021 gatgtcccaa gaccttgtgc cacaaggcca ccaactctat tttctctaaa gctcataaca
     7081 gcaaagccta ccatttggca acaacaacct acagttgctg caccaccagc aagaccacct
     7141 aaacttaaca tcatacaaat agctgcacta cttataggta atgtaagagc tattccaaca
     7201 agtgcagaga ctaaagctcc cattattata ggttgcatag ttgtagcttg cattattata
     7261 tttccaaatg aagtcataaa agcagaaaca gctggaccaa taagttcagc tacaagtact
     7321 ccaattagta ttgtcacagc aggtgtaacc aatatatcta tttttgtttc ttttgaaact
     7381 aattttccaa cctctacagc aaaaagtgta gcgacaaatg ctccaacagg tcctcctaat
     7441 tcattaccac aagctccaac aagtgcacaa gaaaatagta caagtggagg tgcttgaagt
     7501 ccatacgcaa tagccactgc tatagctgga ccagtaacct gtttagcaag agggcttata
     7561 acttcagtaa aaagagaaat attgaaatta tctcctaatg tattgaaaat tgttccaatt
     7621 aaaagggacg aaaaaagacc aagtgccata taacttagtg cgtcaataag atacctttga
     7681 acagaaattt caatattttt tcttttagca aatgatttga aatttctttt tttataattg
     7741 atttccaatt taaaatcctc ctcatataat ataagtataa tttcttttta attaattata
     7801 taacttttca gctgacaaga caaatgttat ttcactaaaa ttagactatt gtaatagtaa
     7861 gaaattaaca ttaattttag ttttaaattt taaatttatg gtttataatt agtataggga
     7921 tattctgaaa tataataatt ttccagttta tcccaatatt taacttaggt agattgctta
     7981 caaaacaaat gattatatat taggctaaaa ggaagtggat agatgatatt tgtaaaaaat
     8041 aagaaataca gaaaaattgc cataattata tctattccta tattgcttgt tgcgcagtac
     8101 taccttttta aatttggaat acttagacca atggtaaagg gagtagaaat tgaaattgta
     8161 gatggggaat atgttaaaga tatagataaa tatgtagtaa aattaaatga aacagttact
     8221 ttgtctacag gtgaatatat taaggttcct tcgtatgcta aaaatccaaa tatttggttt
     8281 aatgtattgg ataactcagg gactttaaaa atagatggaa ataaaatgac agcattaaag
     8341 gttgggtatt cttctgtggg tatcatgaaa aattcaagag tattaaaaaa ggctactata
     8401 aaagtagtag acccagaggt agaatcacta gatatggaga ttaatgggga tttaaaacat
     8461 gttggtgata gtgctactat agaaagtaca atagaagttg attatgataa gtttaaaaaa
     8521 tcatataagc cagtttataa gagtagcaat gaaaatattt taaaaatcaa aggaaataaa
     8581 gtaagtgcag ttggagttgg taaagctaca atatatgcta agtgtggaaa taaagaaatt
     8641 gagagaacat ttaggattca agctagagtt gctgaaataa atatggatga tataaaaata
     8701 gaagttgacc aaaatgaaaa attgaaacca gatataataa cttctccacc tggtttagaa
     8761 ccaccaaaaa tatattatga gttagtagat tcaaaattac ctgtagaaag agcaataagt
     8821 ttaagtagta atggaaatgt tgtaggtctt agagaaggta aagatagggt gagaataact
     8881 tgtggagata aatctaaagt aataacagta acagtagtca aagaaactat aacgaatgac
     8941 tatatacaaa acttggttgg ttcacataaa atagtaaaca ataaagttat tattaaactt
     9001 gaatgggatt atatgaaaga tgtctttgat tatgatatat atcttaaaga taagttgtca
     9061 ggagaatcat ttaagaaaat taaatctata actataaatg aaagtgattt aggtaagtct
     9121 aacaaggtat atgcaactat agaagtagat atgaagggta atcaaaatat agattttgat
     9181 atttatgtca tagggaaaaa ggattcagat acaactaagc caagtaatgt aataaatatt
     9241 actaatggaa atggaaattc aaataatgat aataatatta aagatatgag ggtagaaaat
     9301 atatcagcta atgttgatag agataataat gtcattagag ttaactggag tagtatatct
     9361 cataaggact gtacttacag tatatatgta aaaaataata ctaatggaga tggagaattt
     9421 aatctatatc aaagtgatat acagggaaat gagcatacta taagtattcc tgaaggagat
     9481 ttaaatctag atatttatgt tgttgcaaat tataatggaa atagctctca aaatagtgat
     9541 gttataaatg taagatagat ttgtatacaa attgaaagtg ttgagtttat ttaaatatta
     9601 aattaagaaa aaggatagta tagggtaatt atactatcct ttttttgtta caatatatag
     9661 gtttaaaatc tctagtaata taaattataa aaagtcttat ttacacaaat ctatagatat
     9721 tttttttatt aatcaatatt gtcttaaatt gaacttagtg cggcttctat tgcatgtatt
     9781 actgtcgtat caaatagtgg aatagaagtg tcattttgtt taattaaaag acctatttct
     9841 gtacatccta atataacacc ctctgcacct tgtttgccaa gcttatctat aatagataag
     9901 aaagcttttt ttgaagattc agatataatt cctaagcaaa gttcgttaaa tattgtgtca
     9961 tttactatta tacggtcttc ttcatttgga attaagactt caattccatt attaataatt
    10021 acatttttat aaaaatcttg ttccattgta tatttagtac ctaataaggc cacttttttt
    10081 atttcttttt cccttaatac tgtagcagtt acatctgcta tgtgaagtaa tggaatatgt
    10141 atactttctt gtattttatc tgatacctta tgcatagtat tagtacagat aacaataaaa
    10201 tctgcccctg cctcttgtaa tttaattgca gcatcagcta aaattttggc gcttttttcc
    10261 caatttccac tagattggca ttcttcaatt tcttgaaaat ctacactgta aagtatacat
    10321 ttagaagagt gtagtccacc taatctttct tttattactg tattaataac ttgataatat
    10381 gtaatggtac tttcccaact cataccacca attaagccta tagtcttcat attatacctc
    10441 tcttatttat ttattttgaa atagctattt acaaatacaa gtatagcatc taaaatagaa
    10501 gcatacaata ataaaattgt atggagtaca attataatta agaggagtaa ttatatgcca
    10561 ataaattctt ttgaaaacta tcctatgaca tggaaaccaa aattagataa ccgaaaacca
    10621 ccaatatata aaactttagc aatgttatta gaagaagata ttaaaagagg aaatttaaat
    10681 cctggagata aactgcctcc acaacgggaa ttagcagatt ttctagattt aaacttaagt
    10741 acaataacac gagcatttaa actttgcgaa gaaaagggac taatatgtgc aaaagtggga
    10801 aagggaacat tcatttcttc tgatgtaaat gtaagtaata cattattata tcaaacggaa
    10861 tcaaaagaca taattgaatt agggacagtt catcctccat atgagcaaaa tacatatatt
    10921 attgacttta ttaaaaatgt actaaaacaa ccagaaatgg ataggttttt acaatacatg
    10981 tctccatctg gcacatatat gcaaaaaaag tcaattgcaa aatggataga aagaaataat
    11041 gtatacacca gtgaagaaaa tatattatta tctacaggag ggcaaaatgc tatatgtgca
    11101 actttactag gattatttaa agctggtgat agaattgcta cagattcttt aagtttttct
    11161 ggaattaagt caatagctaa aatgataggt attcaattag tcccaattcc tcaagaaaat
    11221 aatgaaatat cgattgaata tcttgaaagt tattgtaaaa atgaaaatat aaaaggcata
    11281 tatcttatac cagattatca taatccaacg acacatacta tgtctgattt atctcgtaaa
    11341 aagatagcca agatagcaaa gcaatataat ataataatta ttgaagatgc tataaatagc
    11401 atttttagag acggtataca aactcccata ttttctttag ctagtgataa tactatatat
    11461 atttttagta catctaaatt tttatgtgct ggtcttagag tagcatttgt agttgctcca
    11521 aaacgatata tagaaaattt agaaaatgca ctatataata tgaatctaat ggtttctcca
    11581 tttacagcag aaatagtaca tcgtttatta tattctccta ttatagataa aattatagaa
    11641 gagaaaagag atgcaattat agaaagaaat gaagttgctg ataaagtttt gtcagattat
    11701 aatttgattg gtgataagaa ttgcagtttt cgttggttac ttcttcctga tgaattggat
    11761 ggaaaatcat ttgaaatttc tgcaaaaaat ctaggagttc aagtatattg tgctgaacga
    11821 ttttcagtag gaaactctac agttccaaaa gcagttcgta tttgtgtaac agctccaaaa
    11881 gatgtagaag aattagaaaa agggcttaat ataataaagt cacttcttaa gagttaaatt
    11941 tattttacta ttatttaatt aaataaataa aaaggcggag aaatttatta taataaacct
    12001 ccgcttttat tatttaatga aatactttac tttttattaa aaaatttaat tttaataatc
    12061 ttgaaaatat aatcgtttta tggtaaaata attcttaaaa atagaaaaaa ttaatcattt
    12121 gttaaaaaaa atgcataatt tattgtaatt tattgacgaa ggttgaaaaa tattcataaa
    12181 tgtgcgaaat aacagaaaaa atgcaaaaat taattcaatt tcatttgtta taaaatctat
    12241 atggcaaaat taaatctgcc tatcagaatg atataaacac atcagaaagg aggacgctat
    12301 caaataatac aagtagttaa ctttgatagc aaaaaattat gaatgaacaa actagaatat
    12361 ccttagagag agctgctgaa ttaaaatcaa aaattgatga ttatattcag gctagaaaaa
    12421 cgattaacag aggtcttgaa aaagaagaag agataaataa acgaaaacag aaaatattaa
    12481 gtatcttaaa tggaactgaa gaggattgga ataactacaa atggcaatta tcaaatagaa
    12541 taacagatgt agatacttta tcaaaaatta taactctaac taaaaaagaa aaagaatata
    12601 taaaagaggt tggtactcaa tttagatggg caatatctcc atattatttg agtcttatag
    12661 acccagaaga tatatgtgac ccaataaaat tactgtctat accaacacat atagagttgg
    12721 aagatgagca agaagatttg gacccaatgg gagaagagta tacaaaccca gcaggatgta
    12781 taactagaag atacccagat agattaataa taaatgtaac aaatgagtgt gctatgtatt
    12841 gtagacactg tcagagaaga agaaatattg gacaacaaga ttctcataag tcaaaagcta
    12901 ttatccaaga atctatagac tatatcagag aaaatgaaga aataagagat gtactagtaa
    12961 ctggtggaga tgctcttaca ttaaaagatg attatttaga gtggattctt agccaactta
    13021 aagagatacc acatgttgat tatgttagat taggtactag gactcttgtt acaatgccac
    13081 aaagaattac agatgaattt tgcaatatgc taaaaaaata tcaccctgta tatataaata
    13141 ctcattttaa tcatccaatg gaaataacta aggaatctaa agaagcttgt gaaaagttag
    13201 caaatgcagg agttccatta ggaaatcagg cagtattatt aaatggaata aataatgata
    13261 aatttgtaat gagatgttta aatcaagaat tactaaaaat aagagtaaaa ccttattata
    13321 tattccaaag taaacatgta aagggaacaa aacatttcaa tacatcagta gatgatggtc
    13381 ttgaaatcat ggagtattta agaggatata catcaggaat ggctatacca acatatatag
    13441 taaatgcgcc aaaaggagga ggaaagactc ctttgcttcc gcaatacctt gtatcaaaag
    13501 gaacagatta cgttatgctt agaacatggg aaggaaaagt tataaaaatg gaagatgaac
    13561 ctgctgtaga tataaagaaa cttataaaag agcaagcaca ggattaaaaa agtatttaaa
    13621 gtttataaaa agaaacaact ttaaaataaa aagaaaatgg atgtcaaatt tatatcaatt
    13681 tgcatccatt ttttattagt tatttattat tttgttgttg attaactaat tcaagatatc
    13741 cacttgggtg gaagtaatat atctcagaag tattttcatt tacaaagtaa ccaatatcac
    13801 catctgcatc tggtaaaaat acataaccat taagattttt agcttttaat gcttcaaaat
    13861 cactagcatt tccttgatat atgtaatcaa cttcattgtt gtattttact aaaagttctt
    13921 tagcttgttc ttgagtcaat ttagtatttt ggcttacagg aacattcttt tgagaatctg
    13981 cataagaaga ttcatttact ggtgcagtta ataacaaaca agataaaact aataaagata
    14041 taagtgcttt tttcatacta aaaccctctt tcatgtttaa ttatataaga ttcattactt
    14101 aataatattg tatgtttcct ataattaaat attaccatta aagagaataa tattacagtt
    14161 acacagctgt aacttttgat tacaaaatcg taattaaatt gtatttttat tccatttgta
    14221 ttttatcatg tctacgattt acaaactcac agaagtatat ctttataacg cccatcacag
    14281 gagcagatag aatcatacca ggtataccaa agaatcctcc accaacagta actgctagga
    14341 ttgtaaagaa tgggctaaga cctagttgtc cacctacgat ttttggctct ataaatgtaa
    14401 cttcaacttg ttgaattatt attaagtaaa ttaaagaagt taaagcaatt gttggattgg
    14461 agaataaatt aattattaca actggtgcca tacctattac tggaccaaaa tatggaacca
    14521 tattcatgac acccataagt gtaccaaata atagtgcata ttcagatttt aaaaagtaaa
    14581 gaccaattcc agaaagtact ccaactataa aagaatctaa aatcttacct gtaaagtatt
    14641 taccaatatt taaatttaag ctttgacata gttctattat aaagtctcca tattttttac
    14701 ctagggaaat ataaactact ttttttgtaa acagtaagaa tttttctttt tctaataata
    14761 tatagaaaca aattataaaa cctaaaagaa attgtactat aaattttcca actgaaaatg
    14821 tagtgctaaa tatcccacca agtgaaccaa taagcaagtt actaaattta ggcattacac
    14881 tcataatttt gtcaccatac tcttttaatg tattagggtc aactgattgt aaactcttac
    14941 ctaagtcgaa taagaactgc tctgttttat ctatgtatgt aggaatttga gcaactaaat
    15001 cagctaaact atttactatg gatggaactg taaataatat aaaggaaatt agtataacta
    15061 tgagtacacc ataagtaaga agtaacgaat atattctctt aaaatttaat ttactttcta
    15121 agaactttac tagtgggttg aatatatatg ctaatacaaa tgctattata aatggtgtta
    15181 gtagtgacat taataaactt atcactccaa aaaaatattt gtaattatca ataactttaa
    15241 tcaagatata tgaaacaact acagtgagta caatatttag ataaattttt ttatcttgca
    15301 aaataacaca acctttctta tatttattaa atttagatat acttaaatct aagttaaagt
    15361 taatatttat agcttattat acaataaaaa gcagtattaa tatagtatga ttaatatgaa
    15421 attataaata cgttaaaact ttatgcttat agctaaaata ataaaaa
//
LOCUS       DAMJYN010000086        15149 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.090, whole genome shotgun sequence.
ACCESSION   DAMJYN010000086 DAMJYN010000000
VERSION     DAMJYN010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15149)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15149)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15149
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.090"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            <1..391
                     /locus_tag="PC466_002977"
     CDS             <1..391
                     /locus_tag="PC466_002977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDF2770341.1"
                     /translation="AKDLKKVYAAITEEVALSELSLLEEKWGNQYAIALRSWRSNWNE
                     LATYFKYPQEIRTLIYTTNSMESYNRLLRKVTKSKSIFPSDDSLHKSLYLATMDISER
                     WTQKIRNWTQILAHLSIYFEERILTLN"
     gene            868..1479
                     /locus_tag="PC466_002978"
     CDS             868..1479
                     /locus_tag="PC466_002978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770342.1"
                     /translation="MNIKRINLLLSTVMAAVIISLPLAVTANAMEKTESDNNVKIELS
                     DKEVEELHNYWPEDKIFSDEKIDEILIKTGQFTQKELDKINQEVDDSAKKVNQNSRVK
                     YINGYNKYRTFTKNGKNYLYIYVSGKTLKKIKAGTDLASTFGGFLPKIWVELDVVAIG
                     KIITINMDGINTNYGIVLSYIEDKWNFQGATYTYRYDHWFYQT"
     gene            1507..1689
                     /locus_tag="PC466_002979"
     CDS             1507..1689
                     /locus_tag="PC466_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770343.1"
                     /translation="MKKRLYKVFLKTIPNLIIVILSLALSFYTNTFDIDLKILLLIPL
                     AYVLLFIYYYIKTKKD"
     gene            1929..2471
                     /locus_tag="PC466_002980"
     CDS             1929..2471
                     /locus_tag="PC466_002980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDF2770344.1"
                     /translation="MLIYLAILELEEDKIKFEKVYEKYRQIMFYVANKILKDDHLSED
                     AVHNAFLRIIKNIDKIDEVDSPRTKAFIVIIVERIAIDFYRKRKREKVSDIEEEYKNR
                     EINFSIEDKVCESNLAIALAKLNESYFQVLSLKFQYGFSNKEIANALNLGEENVYKRI
                     QRARKKLKEILEEMEVGNIE"
     gene            2503..3165
                     /locus_tag="PC466_002981"
     CDS             2503..3165
                     /locus_tag="PC466_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4367 domain-containing protein"
                     /protein_id="HDF2770345.1"
                     /translation="MLRESIPIATKIIIDDLLSDDELNHVFSKGFERKMKKLIKQQKR
                     SSLTNKIIFYSKQTAIVFLIVLASLLTITMSSEALRSRFFRLVIRVYEDLTSFVFSTN
                     GEDNLSLKNKEPEYIPKGFKEVDRVDDFVITYRNDENIEIQYVTDKISSNSIILDTEN
                     AKVKDIFVNGHKAKYIVKGTFLQLFWNDNNFIYLLNVDYQNSGESEFYEDILIKIAKS
                     IK"
     gene            3355..3672
                     /locus_tag="PC466_002982"
     CDS             3355..3672
                     /locus_tag="PC466_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770346.1"
                     /translation="MKSDLYLCKSNKLYRDNEVLEKFMEDLSFLIDDYKFSLETISIL
                     CKINIEKLTNFYAGKGYILYEEMSLIESVLAPFLSAIDIAKHNYDVVIKSRESDKPLI
                     FEN"
     gene            3694..4137
                     /locus_tag="PC466_002983"
     CDS             3694..4137
                     /locus_tag="PC466_002983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770347.1"
                     /translation="MKRLFALLLTLSLVILPSTLVFANEKAENDSIYAEAPLVFQSNE
                     KAYTHGSGGTAYIGYMSSKHLNWRITSSKGIVILFSGTVEIRNSKNMLVASYPISGGG
                     SSTISGQIDVKYLKKGDYKAILKGTSTTGGGVLVVKSGLVQMFTI"
     gene            4355..4798
                     /locus_tag="PC466_002984"
     CDS             4355..4798
                     /locus_tag="PC466_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770348.1"
                     /translation="MNLRKTVISGMCALVCSSAVAIPAFADEYQDKNIEQYSAVNYID
                     DTMVKMSYIKSGTCNLSISGSTAKVTCFVRGASNVTSTSIIARLQKSNDNGKTWSTIQ
                     TWNASGNISCSLSKSKTIGKGYYRVHSTIKANSESKNIISSTKKY"
     gene            complement(4929..5349)
                     /locus_tag="PC466_002985"
                     /pseudo
     CDS             complement(4929..5349)
                     /locus_tag="PC466_002985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894307.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
     gene            complement(5327..6604)
                     /locus_tag="PC466_002986"
                     /pseudo
     CDS             complement(5327..6604)
                     /locus_tag="PC466_002986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899679.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
     gene            complement(6627..7169)
                     /locus_tag="PC466_002987"
     CDS             complement(6627..7169)
                     /locus_tag="PC466_002987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770349.1"
                     /translation="MLLCDPASAGGSKHDYSAFLVGSESENGLLCGRLAELAKINART
                     DFDKYILHMIYLLKVYPDITHVYIEKNTFNGTAANQLELKIKNDDVLYYRDIEIINEH
                     QKKNKDDKISTLIPVLNKGQMIFAEEDKAFIQQILNFTGQKYSLHDDAPDISAEFINR
                     IFNIKVNESITLLDRRNLGL"
     gene            complement(7209..7427)
                     /locus_tag="PC466_002988"
     CDS             complement(7209..7427)
                     /locus_tag="PC466_002988"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770350.1"
                     /translation="MLFDFKNTNHLEDAKEFYWENEKEIKFPILWPSFWNCLDMALSY
                     YENPTSFKQEVQNDVNSIGEKWFKTIRT"
     gene            complement(7623..8366)
                     /locus_tag="PC466_002989"
     CDS             complement(7623..8366)
                     /locus_tag="PC466_002989"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770351.1"
                     /translation="MDNLERNIQLIFSYMAKTFIRNGATIREAEKEANEIIKTNSSNL
                     WGVNGLAYQLGKINLEFFCMYFIQDTYLPKEDNVAAPIAKVHHELWEDIQESIIGDGS
                     QQLGRIYPRGTGKSAFGDLATTVWSHCYKHKTYTLICSDIGSTAEKFVKDIKNALLEN
                     EYIKKAFGVLLNDNDRKYICNSTQLELTNKTFIEAISSSSPMRGKKYNNNRPDLIILD
                     DYQSEENVRTEDAREKKFKKFSDDVKYAA"
     gene            complement(8666..9223)
                     /locus_tag="PC466_002990"
     CDS             complement(8666..9223)
                     /locus_tag="PC466_002990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDF2770352.1"
                     /translation="MVVGYMRVSTAEQNEDRQLVTMKKHNVEKMYQEKISAKDTKRSK
                     LNAMLDFVREGDTIIVHDFSRLARSTKDLLEIVELLEKKHVKLISDKENLDTSTPTGK
                     LMLTMLGAIYEFERTNMLERQREGISIAKEQGKYKGRKEVKIDNFGSYYDRYKTRELN
                     KTQLAKELGVSRPTLDRLIKSHESN"
     gene            complement(9418..9606)
                     /locus_tag="PC466_002991"
     CDS             complement(9418..9606)
                     /locus_tag="PC466_002991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770353.1"
                     /translation="MNNKKKSFLISGTINVILLIIVFALFSYNIIENSTRNMIITVIL
                     IFIFEIIKIKILEKYYNL"
     gene            complement(9617..10192)
                     /locus_tag="PC466_002992"
     CDS             complement(9617..10192)
                     /locus_tag="PC466_002992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770354.1"
                     /translation="MLKKKIISFLMAGIFVLSSGYNLVYASTFEENEYKQELVNENEF
                     TIINSNENEMIVDKKGNNTYVSTKVTPGSWKNVKYLGQKSRKLSSPYTRERIIQTIQW
                     GLGYLSGGSSFLLGLAESIYREKVYDITKYGGVYTKTYYRRQITDIRNSHANVPVPYR
                     YEYVTYFYSSSNFKKVVYTERVGDGIKLANN"
     gene            complement(10525..11664)
                     /locus_tag="PC466_002993"
     CDS             complement(10525..11664)
                     /locus_tag="PC466_002993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HDF2770355.1"
                     /translation="MVIKLTIEEYKNKYSTGDKIILSLKSFDNKELYYHETDNILNSK
                     DEIDRLTSSKIFKIIEDKNDLALESYYSSVIEGAFSTRKIAKSIIRGKMKPSNKSEYM
                     IYNNHRALEYGLDNLDKLYSHKFIYNLHHILGENCLDSEEYEYRTEKVYVCDSKGEII
                     HTGLDPLKIYNFMDELIIFMENSKVNDLVKSTIIHFYFVYVHPFSDGNGRTSRALSYL
                     YLINKGYDTFKEFSISYIISKNRTKYYKAILDVENKGYNLTVFIEFMLKSIIQSINEM
                     RDMHDRKSLESILKEELFENDITLSATEEHILKYICSKDNYSMTLENYIKKNKGRYLK
                     AGIKEIELVDQLMEVFNNLEEIEILSREKDVYKVNEKYLNMLEIS"
     gene            12001..13254
                     /locus_tag="PC466_002994"
     CDS             12001..13254
                     /locus_tag="PC466_002994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase domain-containing protein"
                     /protein_id="HDF2770356.1"
                     /translation="MLNKKNISSIIMTMILSLSTTVFVFADENTNVKGQDVTKYNEEM
                     VSKNLEDLSIEQLIDIRDKAIDKNLEGLRKFGEDSVKERKDSILNFEFGLVAFVNKNY
                     SNLTEKEKLIRQINIVEYENSINDIMDPSGDFFKVTNQSYQINEFVLKNGKNYKEWSY
                     EYVEFLIEHLEDLCNFVDFDAKYVIEMVDPSIKPDLSDNQKKSLNNELIKMYSSNTLS
                     TNIKDEIENWENNLNINEKNSNEPLPRVSPSSYRQQALAYAKKHGYTNGYYGSTNRKN
                     NAPSPYYNFQKDGYGDCANFVSQCLHEAGVTFWTNNNPWYYYSTSNRSPSWAGAREFK
                     IHWMNRIAYQTLTVSNSLSFLRPATPVSILNSSGVATHTLISTDKHSNGYNFSYAAHS
                     DEGARTNLLKKLEGKKISYYKVYWE"
     gene            13588..14319
                     /locus_tag="PC466_002995"
     CDS             13588..14319
                     /locus_tag="PC466_002995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770357.1"
                     /translation="MLNKKNVSLIVLVIVLSLFTAIFVFNNRNTNDKSKEIAKNNEEI
                     VPKNLEALSIEQLTKIRDKAIDKNLEGLREFGEDSVKQRKDSILNFEFGLVAFVNKNY
                     SNLTEKEKLIRQINIVNYENSINDIMDPSGSFFELANQSYEINEFMLKNKKNYKEWSY
                     EYIEFLIDHLDELCKFVDFDIKDVIDIIDPTIKTDLSEEQKKSLNDKLKKVSSSDTLS
                     EDIKKEIKNWENNLNSLNMNKNNSN"
     gene            14561..>15149
                     /locus_tag="PC466_002996"
     CDS             14561..>15149
                     /locus_tag="PC466_002996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HDF2770358.1"
                     /translation="MFNKNEILKKLIEEYDVKTTTDIQDMLKDLFASTIHQMLEAELD
                     DHLGYDRYGNKNKNTKNSRNGYRNKNVKSDFGEITLNIPRDRNGDFEPKVISNYKNDI
                     SGIENQVIGMYSKGMSTRDISSHLKSIYGIDISHSLVAKITDRVLPLAHEWQNRPLDM
                     VYPIVFMDAIHYKVRSEGRIINKAAYIAIGVNLEGI"
BASE COUNT         5629 a         1915 c         1942 g         5663 t
ORIGIN      
        1 tgcaaaagat ttaaagaaag tatatgctgc aattacagag gaagtagcat taagtgagct
       61 atcgctctta gaggaaaaat ggggtaatca atatgcgata gcattaagaa gttggcgaag
      121 taattggaat gagctagcaa catactttaa atatcctcaa gagataagaa cattgatata
      181 tactacaaat tcaatggaaa gttacaatag attattaaga aaagttacta aatcgaagtc
      241 tatttttcct tcagatgatt ctttgcacaa atcattatac ttagcaacta tggatatttc
      301 tgaaagatgg actcaaaaga ttagaaattg gactcaaatc ttagctcatt taagtattta
      361 ttttgaagaa agaattttaa ctctaaatta ataaagaaat atttcaaaaa aattaagaaa
      421 ttttcttaaa gggataataa tttttacaaa aatggaaaaa atatcaaaat aaggctatga
      481 tttttaaagc catagcctta ccaataaatg tttaattatc actaaaaaaa taaattttta
      541 ttcaaagaat acacataaat atttccagac tcacttattg tataagttat attctatttt
      601 gtatgaagtc aattaaaaac tgaactatat taaaattaat tttataaata acaaatataa
      661 ataattacaa aaccttaact gcgttaagtt tgaaatataa taatattaaa aacacttctc
      721 tcaaatcaag tatcttttgt tatattttca taagttttaa aaatataaat tttttaaaac
      781 ttgtgtccaa aaaacaaaat taaatatgtt atatatgtaa agggttaatt ttaaaacctt
      841 aaatttatta tagttagggg gatttaaatg aatatcaaaa gaattaatct ccttttatca
      901 acagtgatgg cagctgtgat aatatcttta ccacttgctg ttacagcaaa tgcaatggaa
      961 aaaacagaat cagataataa tgtgaaaata gagttgtctg acaaagaagt agaggaatta
     1021 cataattact ggcctgagga taaaattttt tcagatgaaa agattgatga gatcttaatt
     1081 aaaacaggtc aatttactca aaaggaattg gataaaatca atcaagaagt ggacgattct
     1141 gctaagaaag taaatcaaaa ttctcgtgtg aaatatataa atgggtataa caaatacaga
     1201 acttttacta aaaatggtaa aaactattta tatatttatg taagtggaaa gacattaaag
     1261 aaaataaaag ctggaacaga tcttgcatct acttttggag gttttttacc aaaaatttgg
     1321 gtagagcttg atgtagtggc aattggaaag ataataacaa ttaacatgga tggtataaat
     1381 actaattatg ggattgtttt atcatatata gaggataagt ggaattttca gggtgcaaca
     1441 tatacttata gatatgatca ttggttctat caaacttaaa agacatgctt ttttaggagg
     1501 aataatatga aaaaaaggct ttataaggtt tttttaaaaa caattccaaa cctgataatt
     1561 gtgatattat cacttgcatt atcattttat actaatacat ttgatattga tttaaaaata
     1621 ttgcttttaa tacctttagc atatgtactt ttgtttatat actattacat caaaacaaaa
     1681 aaagattaat ttttatggaa ttagatatat acgaaaataa ttaatttaaa aatttaactt
     1741 tgagaatcat ttgtagagtt aaggccctta taatcccgaa aatggatttg aagggccttt
     1801 ttactagata tctttaaaaa gcttgttaag catagttata ttctatttaa gtagagttaa
     1861 ttatatattt atgttataat tgaactttaa aatattaatt cagaattttt atattggagg
     1921 aattctaaat gttaatttat ctagctatac ttgaactcga agaagataaa ataaagtttg
     1981 aaaaggtata tgaaaagtat agacaaataa tgttttatgt agccaataaa atattaaagg
     2041 atgatcattt atcagaagat gcagtacata atgctttttt aagaataatt aaaaatatag
     2101 ataaaattga tgaggtagac agtccaagaa cgaaggcttt tatcgttata atagtagaaa
     2161 ggattgctat agacttttac agaaagagaa aaagagaaaa ggtatctgat attgaagaag
     2221 agtataaaaa cagggagata aatttttcta tagaagataa agtatgtgaa agtaatttag
     2281 ctatagcact tgcaaaactt aatgaaagtt actttcaagt gctttcctta aagttccagt
     2341 atggtttttc aaataaagaa atagcaaatg cattaaattt aggggaggaa aatgtatata
     2401 agagaattca gcgtgctaga aaaaaattaa aagaaatatt agaagaaatg gaggttggaa
     2461 atattgagta ataaaaaaga tgattttgat attacggatg atatgcttag agaaagtatc
     2521 ccaatagcga caaaaattat tattgatgac cttctttcag atgatgaatt aaatcatgtt
     2581 ttttcaaaag gttttgagcg aaaaatgaaa aaactcatta agcaacaaaa aagaagtagt
     2641 cttacaaata aaatcatttt ttattcaaaa caaacagcta ttgtattttt aatagtttta
     2701 gctagtttac ttactattac tatgagtagt gaggcattgc gttcacgttt ctttagatta
     2761 gtaataagag tatatgaaga cttaacttca tttgtttttt caactaatgg agaagataat
     2821 cttagtttaa aaaataaaga acctgagtat ataccaaaag gatttaaaga agttgataga
     2881 gttgatgatt ttgttattac atatagaaat gatgaaaata ttgagataca atatgtaaca
     2941 gataaaatta gttcaaattc tattatatta gatacagaaa atgcaaaagt taaagatata
     3001 tttgtaaatg ggcataaagc aaaatatata gtaaaaggaa ctttcttaca gttattttgg
     3061 aatgacaaca actttatata tttattaaat gtagattatc aaaatagtgg agaatctgaa
     3121 ttttatgaag atattttgat aaaaatagcg aaaagtataa aataattttt ttaagtgtcc
     3181 aagggtagcc tcttcattcg ttatacaagt atatatgaaa atgtgaggtg atttttatgg
     3241 ttttaaaatc tacatttacc tgagcgttaa aaatattgtt ataggaaaaa ttaatacatt
     3301 atagttataa catgcttgca ataggaataa aactttaaaa ttgaggtgta aaaaatgaaa
     3361 tcagatttat atttatgtaa aagtaataaa ttgtatagag acaacgaagt tctagaaaaa
     3421 tttatggaag atttaagttt tcttatagac gattataaat tctcgttaga aacaatatct
     3481 attctatgca aaataaatat tgagaaatta actaatttct atgcaggaaa aggatatata
     3541 ctgtatgaag aaatgtctct tattgaaagt gtacttgcac cttttttaag tgcaattgat
     3601 attgctaaac ataattatga tgttgtcatt aaatcgaggg aaagcgataa acctttgata
     3661 ttcgaaaatt aatttaaaac tgggggaata cacatgaaaa gattatttgc gttattactt
     3721 actttaagtt tagttatatt accatcaact ttagtatttg ctaatgaaaa agctgaaaat
     3781 gattcaattt atgctgaggc gccattagtg tttcaaagta atgaaaaagc atatacacat
     3841 ggtagtggag gaactgcata tataggttat atgtcaagta aacatcttaa ttggaggata
     3901 acatcttcaa aaggaatagt tatactattt tcaggaactg ttgagattag aaattcaaaa
     3961 aatatgcttg tagcatcata tccaataagt ggtggaggat cttcaactat atctggacaa
     4021 atagatgtta aatatcttaa aaaaggggat tataaagcta tattgaaagg tacaagtaca
     4081 acaggaggcg gagtcttagt agtaaaatct ggtctagttc agatgtttac aatttaatat
     4141 tataagtaaa ataaaaatca tgaatttatt gggggatagt cacaatacat attatttaca
     4201 gatattcata actattatag ttaaagacat tctattataa agaaaatgta taatttaaaa
     4261 ttataataaa aaaaattatc attagtgtcc aaaaatcact tcttcattcg ttatataagt
     4321 tatataaata gaaaacaaat gaagaggtga ttttatgaat cttagaaaaa cagttataag
     4381 tggtatgtgt gctttagtat gttcatcagc agttgcaata cctgcatttg ctgatgaata
     4441 tcaagataag aatattgaac aatattcagc agtaaactat atagatgata ctatggtgaa
     4501 aatgtcttat attaagtctg gtacttgcaa tttaagtatt tcaggaagta cagctaaagt
     4561 aacatgcttt gttagaggag catcaaatgt tacaagcaca tcaattattg ctagattaca
     4621 gaaaagcaat gataatggga aaacatggtc aacaatccaa acatggaatg cttcaggaaa
     4681 tatttcatgt tctctttcta agtcaaaaac tataggaaaa ggatattaca gagttcattc
     4741 cacaataaaa gctaactctg aaagtaaaaa tataataagt agtacaaaga aatattaaaa
     4801 atagatattg tatttatgag ttgtagtaaa caagaataat agttttttaa aagcaaatat
     4861 aattaatttt aaatagagtg ccaatataaa ataggtgtat aatatttata cttttttata
     4921 ttggcactct attttataaa ataagttatt atagaaaatg aaacataatt tatatataaa
     4981 ttttctgttt gacctggtat ataatctttt atatcacata tcagtatttt cccatcatta
     5041 taaccccaac caatcacagt tgcaggtatc atatcagctt ctccatcata aatgattgta
     5101 tgtttataca tgatttttcc ctcgctatta tctatagttt tattcaaaat accttctgct
     5161 attaatttag caactatgtc tttaatagtc tgtatctgct ttactgtcta caaaacatac
     5221 ttcaattaat atcgctggag cttttgtatg actaagccaa tacaattccc ttacgtccga
     5281 ttttgcacct ctattttcag cagatttata tatatcttca gtcaatttag ttataatctt
     5341 ttgattcatc taataaaatc tctccctctg aaactatttc ctgttctttt ttagcctttt
     5401 ccatttctgc atgaggatta tcaataaaac ttggttgaga taatccggtt tcagtagata
     5461 atttatctcc aagttgactt aatatatttg ctacaactaa atcattatgt ggtatcttag
     5521 gggtaaattt agccttaata tctttataat catagtcaaa accatatttt ttattaagcc
     5581 aaatgcacaa taatttgtac ctattaaata aagtatctgc aatactatca ttattctggc
     5641 tacaaatcca ttctgtactg attaatcttg ctacaactgc taaacttgat gtattacttt
     5701 gcattttttc attgtgattt atatgagatg taattttata tatgttttct tttattgaag
     5761 atagtgtatt ttgaacaaat gtatcattca tgtctttaat aagccattct atttttccat
     5821 ctccattaac ttgaagtatt ccaagttctt tcatccttgg caaatcatct tctttaatat
     5881 tacattcaga gaaggttaaa taagcatttc taaaatcact aatttcatta cttatatcac
     5941 ttaaattagt ttcataagca tcttgtaatc cttttatatc attgaatatt gtattttttc
     6001 ctagttcttc acttctttta caaattgata ttggaacatt accattaaat atattattta
     6061 ctgtaggttt ttctatctct ttaaaatttg aatcaaaatg atatatgtat tctttatcat
     6121 atacatctat ataaatatca tctttaaaat cttttttaaa ttctctaaaa aaatagatgg
     6181 tctctccatc ttcattttca taatggcagc catctgttgg ttttattatt cttactttca
     6241 tttcattgtt ttttacatag taaagttcat agcaaaatcc aaataatagt gtatatctca
     6301 ataaatctga atcgtgcttt ttactccaat ggcaagtata gtattctaaa tcatttataa
     6361 tcttctcatc acctaatcta cttgtatagg tgattttatt tgcaagagaa taagcgacct
     6421 cttcattaat aaactttttt aagaaattag tgtttatctt attattagac ctcttggtaa
     6481 ccattttata gttactaata gcatctgttt cacctttata atacttatac atagtgttgt
     6541 attcttgctt ttttaaactc tagtcttcat atatttctct taataaactt aaatctattt
     6601 ccatttaatg catcacctcc atacaatcaa agacctaaat ttcttctatc taatagtgta
     6661 atactttcat ttactttaat attaaaaatc ctatttataa attctgctga tatatctggt
     6721 gcatcatcat gtagagagta cttttgtcct gtaaaattaa ggatttgctg tataaatgcc
     6781 ttatcctctt ctgcaaaaat catttgacct ttatttaaaa caggtattaa agtagagatt
     6841 ttatcatctt tatttttctt ttggtgctca ttaatgattt ctatatctct gtagtaaaga
     6901 acatcatcat tttttatttt aagttctaat tgattagcag ctgtaccatt aaatgtattt
     6961 ttttctatat aaacatgtgt tatatctgga tacactttta ataaataaat catatgcaat
     7021 atatatttat caaaatcagt tctagcattt attttggcta gttctgccaa tctgccacat
     7081 agtaaaccat tttctgattc acttccaaca agaaaagcac tatagtcatg tttagaacca
     7141 cctgcagatg ctgggtcaca taataacatt gtctttttga atgtatgagt ttctatacat
     7201 tctctagatt aagttctgat tgttttaaac catttctcac ctattgaatt tacatcattt
     7261 tgtacctctt gtttaaaaga tgttgggttt tcgtaataac ttaaagccat gtctaaacaa
     7321 ttccaaaaac ttggccataa tataggaaat ttaatttctt tttcattttc ccagtaaaat
     7381 tctttagcat cttcaagatg atttgtgttt ttgaaatcaa ataacaactc tttgaaatta
     7441 agccataaac cagaattaaa taattcatct acattatcaa ctaaaactcc tttttcacat
     7501 ttaaatttcc aagttggtaa attctttagc ctactataga aacattcttt atgttgtaag
     7561 gttcctaatg ctataaaagt tgttcctctt tttataatct taccatttct tattactggt
     7621 ttttaagcag catattttac atcatcagaa aattttttaa attttttctc tctagcatct
     7681 tctgttctaa cattttcttc tgactgataa tcatcaagta tgataagatc tggacgatta
     7741 ttattgtatt tttttcctct cattggtgat gaagatgata ttgcttcaat aaaggtttta
     7801 ttagttaatt ctaattgagt actattgcaa atatattttc tatcattatc atttaagaga
     7861 actccaaatg cttttttaat atactcattt tcaagtaatg cattttttat atcttttacg
     7921 aatttttctg ctgtagagcc tatatcagag caaattaaag tatatgtctt atgtttataa
     7981 caatgtgacc atacagttgt tgctaaatct ccaaatgcac ttttacctgt tcctcttgga
     8041 taaattcttc ctaattgctg tgaaccatct ccaattatag actcttgtat atcttcccat
     8101 aactcatgat gaactttagc tataggagca gcaacattat cttcttttgg taaatatgtg
     8161 tcttgtataa aatacataca gaaaaattct aaatttattt ttccaagctg ataagctagg
     8221 ccattaactc cccaaagatt gcttgaatta gtttttataa tctcatttgc ttctttttca
     8281 gcttctctta tagttgctcc atttcttata aaggtctttg ccatataact aaatattaat
     8341 tgtatatttc tttctaaatt atccactcgt atttacttcc tcttaattct tctatttttt
     8401 taggttcagt gagtaataca attaataaaa taaacaatgc aaattttttt ctaataaaat
     8461 caccctcttt gaaatatgtc tctggttttt aatttttgct agaaaatttc tagaactcat
     8521 tttctataaa taatactttt ttgaaataga aggatacccc ctatactgaa aaacagttat
     8581 ttataattat tttaaacata attaaagggc ataattctat gaatttgccc cactaaaatt
     8641 aacttaagca tatatattgc tcttcttagt tactctcatg gctctttatt aatctatcta
     8701 atgttggtct acttactccc aattctttag ccaattgagt cttattaagt tctctagttt
     8761 tatatctatc ataataacta ccaaagttgt ctatcttaac ttctttacgt cctttatatt
     8821 taccctgttc tttagctata gagatacctt ctcgttgtct ttctaacatg tttgttctct
     8881 caaattcata tattgcgcca agcattgtaa gcataagttt tcctgtaggt gtacttgtat
     8941 ctaaattttc tttatcacta attaacttta catgtttctt ttctaagagc tcaactattt
     9001 ctaataagtc tttagtactt ctagcaagtc tactaaagtc atgtacaatt attgtatctc
     9061 cttctcttac aaaatctaac attgcgttta gttttgatct tttagtatct ttggcactta
     9121 ttttctcctg atacattttt tctacattat gctttttcat tgtaactaat tgtctatctt
     9181 cattttgttc tgctgttgaa actctcatat aacctactac catctttgat acctccacct
     9241 atgtttactc tataaataat attatagcat aaatgtaaaa ctagagttaa agatttgcca
     9301 tgctttttgt aaattaattg gagttttgat tttattttta catcagaata gatagtttgt
     9361 aatgtaaatt tgtaccagca tactttacaa tatgctctta ggaaagatat ttcttgttta
     9421 tagattataa tatttctcta gtatctttat ttttataatt tcaaaaataa aaattaaaat
     9481 tacagttatt atcatatttc gtgtactatt ttctataata ttataactaa acaatgcaaa
     9541 aacaatgatt aataaaatta cgtttatagt gccagaaatc aagaatgatt ttttcttatt
     9601 attcatatat ttcctcctag ttatttgcta gttttatacc atctcctact ctttcagtat
     9661 atacaacttt tttaaagtta gatgagctat aaaaatatgt aacatattca tatctgtatg
     9721 gaacaggaac attagcatga ctgtttctaa tatcagttat ttgtctccta tagtatgttt
     9781 ttgtatatac gcctccatat ttagtaatgt catatacttt ttctctataa atactctcag
     9841 ctaaacctaa taaaaaagat gaccctccag aaagataacc taatccccat tgaatagttt
     9901 gtataattct ttctcttgta taaggagaac ttaatttgcg tgatttttga cctagatatt
     9961 taacattttt ccaactacca ggtgtaactt ttgttgaaac ataagtgtta ttgccttttt
    10021 tatccacaat catttcattt tcattgctat taataatagt aaattcgttt tcattaacaa
    10081 gttcttgttt atattcattt tcttcaaaag tagatgcata aaccaaatta tatccactag
    10141 ataaaacaaa tattcctgcc attaaaaaac ttattatttt tttctttaac ataatatttt
    10201 actaccttta cttaaatatt tattctataa acactgtcat ataacctgtt agttatatta
    10261 aaaataatct ttttatataa cttcacaatc aaaccttgtc ttatttcata atagttttat
    10321 ttaatatcat ataatttaga cctccttata agattattta tatatataac gaataataaa
    10381 agtaattttg gacaaaataa aaatcttttt attttaagaa tgaaaaattt aaccctctaa
    10441 gaaaactcaa ttaagagcga ttcatagagg gcttattatt atattatata actttatata
    10501 ctttttattt ttatatgctt caatttaact tatttcaagc atattcaagt acttctcatt
    10561 aactttatat acatcctttt ctctagataa aatctctatt tcttcaagat tattaaacac
    10621 ttccatcaac tggtcaacta attcgatttc ttttattcca gcctttaagt atctaccttt
    10681 attctttttg atatagttct ctaatgtcat agaataatta tctttactac agatatattt
    10741 taatatatgt tcttctgttg ctgatagagt tatatcattt tcaaataatt cctcttttaa
    10801 tatactctct aaagacttcc tatcatgcat atcacgcatt tcattgatag attgtattat
    10861 agactttagc atgaactcta taaatacagt taaattatat cctttattct ctacatctag
    10921 tatagcctta taatacttag ttctgttttt agatattata tatgatattg aaaactcttt
    10981 aaaagtatca tatcctttat taattaaata tagatatgat aaggctcttg atgttcttcc
    11041 attaccatca ctaaaaggat gaacatatac aaagtagaaa tgaattattg tactctttac
    11101 taaatcattt actttactat tttccataaa aattattaat tcatccataa aattatatat
    11161 tttcaaagga tcaagtcctg tatgtataat ctcacctttt gaatcacata catatacttt
    11221 ttcagttcta tattcatatt cttctgaatc taaacagttt tcacccaata tatgatgtaa
    11281 attatatata aatttgtgac tatataattt atctaaatta tctaatccat attctaaggc
    11341 tctatgatta ttgtaaatca tatactcact tttattactt ggtttcatct ttcctctaat
    11401 tatagatttt gcaatctttc tagttgaaaa ggcaccttct attacactag aataataaga
    11461 ctctaaggct aaatcatttt tatcttctat tattttaaat atcttgcttg atgttaatct
    11521 atctatttca tcttttgaat ttaatatgtt atcagtttca tgatagtata gttctttatt
    11581 atcaaaactc tttaaggaaa gtataatttt atctccagta gagtatttat ttttgtattc
    11641 ttctattgtc agtttaatca ccaccttagt ttatctttat ctattaatat taacaaaaag
    11701 tattagtttt tacactattt ttgattgttt attttatata ttatgattct actcttgata
    11761 attaaatctt acttaaaaat taattcttga taattaataa aaaaatttat atataagtgt
    11821 ctaaaaaacg attctttatt cgttatatat ataaataata ctagaaaggg aggattatat
    11881 tatgatattt agtaaacgct cttttagaaa aaaacggtga taaacttgtt ttaaatttta
    11941 gtagaatatg atttttgttt tggcaagtat taatacatat attaaagagg gaggtttaat
    12001 atgttaaata aaaaaaatat aagttcaatt attatgacaa tgattttaag cttatcaact
    12061 actgtatttg ttttcgctga tgaaaatact aatgtgaaag gacaagatgt aaccaaatat
    12121 aatgaagaaa tggtctctaa aaacttagaa gatttaagta tagaacaatt aatagatatt
    12181 agagataaag ctattgataa aaatttagaa ggtcttagaa aatttggaga agattcagtg
    12241 aaagaacgta aagattcaat tttaaacttt gaatttggat tagtagcttt tgttaacaaa
    12301 aattatagta acttaacaga aaaagagaaa ttaataagac aaatcaatat tgttgagtat
    12361 gaaaattcta taaatgatat aatggatcct tcaggcgatt ttttcaaagt aacaaaccaa
    12421 agttatcaga ttaatgaatt tgtattaaaa aatggaaaaa actataaaga gtggtcgtat
    12481 gaatatgtag agtttttgat tgagcattta gaggatttat gtaattttgt agattttgat
    12541 gcaaaatatg taatagaaat ggttgatcct tcaataaaac cagatctttc agataatcaa
    12601 aagaaatctc taaataatga attaataaaa atgtattcaa gtaatactct aagtacaaat
    12661 ataaaagatg aaatagaaaa ctgggaaaat aatttaaata ttaatgagaa aaattcaaat
    12721 gaacctttac caagagtaag cccttctagt tatagacaac aagcattagc ttatgctaaa
    12781 aaacatggct atactaatgg ttattatggt agtacaaata gaaaaaataa tgcaccttct
    12841 ccatattata attttcaaaa agatggatat ggagattgtg ctaactttgt ttcacaatgc
    12901 ttacatgaag ctggagtaac attctggacg aataataatc catggtatta ttattctact
    12961 agtaatagat caccttcttg ggctggagca agagaattta aaatacattg gatgaatcga
    13021 attgcatatc aaacacttac tgtatcaaac tctttaagtt ttttaagacc agcaacacct
    13081 gtaagtatat taaatagtag tggagtagca actcatacac taatatctac agataagcat
    13141 tcaaatggat ataatttttc atatgctgca cattcagatg aaggtgcaag aacaaatttg
    13201 ttaaaaaaac ttgaaggaaa gaaaatttct tattacaaag tttattggga ataaataaaa
    13261 atttatactt ttaattaaat gaaaattgaa aagaataaat atctatttca agatccaata
    13321 agtatttagt tgaagcagct attaaatttt attacataat cataaaaaag agactagtgg
    13381 aatttagtct cttttttatg atttaaaaat ttaataaaag aattatataa atttgtctaa
    13441 aaattagttt atcattcgtt ataattatat aaactatatc aaaaaagtgt tctattgtat
    13501 tctttagaat aatcagtaat aaaggttatt ctaataaact gagttatttt ttcacaaata
    13561 aaatacttat taaaaaggag atttgatatg ttaaacaaaa aaaatgtaag tttaattgtt
    13621 ttagtaatag ttttaagttt attcactgct atatttgttt tcaataatag aaatacaaat
    13681 gataaatcaa aagaaattgc taaaaataat gaagaaatag tgcctaaaaa cttagaagct
    13741 ttaagtatag aacaattaac aaaaattaga gataaggcta ttgataaaaa tttagaaggt
    13801 cttagagaat ttggagaaga ttcagtaaaa cagcgtaaag attcaatttt aaattttgaa
    13861 tttggattag ttgcttttgt taacaaaaat tatagtaact taacagaaaa agagaaatta
    13921 ataagacaaa ttaatattgt taactatgaa aactctataa atgacataat ggatccttca
    13981 ggttcattct ttgaattagc aaatcaaagt tatgaaatta atgagttcat gttaaaaaac
    14041 aaaaaaaatt ataaagaatg gtcatatgaa tatatagaat tcttaattga tcatttagat
    14101 gaattatgca aatttgttga ttttgatata aaagatgtaa tagatattat tgatcctaca
    14161 ataaaaacag atctttcaga agaacaaaag aaatctttga atgataaatt aaagaaagtg
    14221 tcttcaagtg atactttaag tgaagacatt aagaaggaga taaaaaattg ggaaaacaat
    14281 ttgaatagtt taaatatgaa taaaaataat tctaattaac tgatagtgta aaatgtacat
    14341 aattataaat aaaataggga tgtcttaaaa ttgattattt tctaatctaa atattttagg
    14401 cctatctaaa aacataagat tatggtctaa aatttgaaat tttagaccat gctttatctt
    14461 tacaataaat gggtctttaa aataaagtgt gtattcttct aaaaagtggt gataattaaa
    14521 atattaaata tcactatata aaggaaggtg cacacttttt atgtttaaca aaaacgaaat
    14581 attaaaaaaa cttattgaag aatatgatgt taaaacaact acagatattc aagatatgct
    14641 aaaagattta tttgcgagta caattcatca aatgttagaa gcggagcttg acgaccattt
    14701 aggttatgat agatatggca ataagaataa aaatactaaa aactctagaa atggatatag
    14761 aaataaaaat gttaaatcag attttggaga aataacttta aatattccaa gagaccgaaa
    14821 tggagatttt gaaccaaagg taattagtaa ttataaaaat gatatatcag gaatagagaa
    14881 ccaagtgatt ggaatgtact caaaaggcat gtctactcga gatatatcaa gccaccttaa
    14941 gagtatttac ggaattgata tatctcattc tctagtagct aaaattactg atagagttct
    15001 acctttagct catgaatggc aaaacagacc tcttgatatg gtttatccaa ttgtatttat
    15061 ggatgctata cattataaag ttagaagtga aggtagaata ataaacaaag ctgcatatat
    15121 agccataggt gttaacttag aaggtataa
//
LOCUS       DAMJYN010000087        14888 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.091, whole genome shotgun sequence.
ACCESSION   DAMJYN010000087 DAMJYN010000000
VERSION     DAMJYN010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14888)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14888)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14888
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.091"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(109..645)
                     /locus_tag="PC466_002997"
     CDS             complement(109..645)
                     /locus_tag="PC466_002997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB-like nuclease domain-containing protein"
                     /protein_id="HDF2770359.1"
                     /translation="MEYKSPVYGIIAVPIEKIESNDYNPNAVAPPEMQLLYKSIKEDG
                     YTMPIVCYYNEEKDKYIIVDGFHRYRVMLENKDIYDRENGLLPVSVIDKSLDERMAST
                     IRHNRARGSHNVDLMSKIITELCEIGKSDEWISKHLGMEVDEILRLKQITGLAYLFKD
                     KEFGNAWIPFGSDIEEEN"
     gene            complement(663..1976)
                     /locus_tag="PC466_002998"
     CDS             complement(663..1976)
                     /locus_tag="PC466_002998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3440 domain-containing protein"
                     /protein_id="HDF2770360.1"
                     /translation="MDKRYLESDVFEAFQERLSYLFNEFDYIYVSFSGGKDSGLLLNL
                     VLDYKRKNNISSKIGVFHQDFEAQYSLTTEYVEKVFEENIEDIEPYWVCLPMATRTAV
                     GNYEMYWYPWDDEKEELWVREMPVKEYIINQKNNPFTYYKYKMRQESLAKQFGRWIRD
                     IHEGAKVVCLLGTRAAESLQRYCSIVNKQHGYKGKCWITKEFKNVWTASPIYDWEIED
                     IWLAHYKFDYDYNKIYDLFYKAGVAPRKMRVASPFNDSAKESLNLYRILDPDVWVKLV
                     ARVQGVNFTSIYGKTKAMGYRSVKLPYGHTWKSFTYFLLDTLPENIRNSYIKKFSTSI
                     EFWQNTGGGLSEIVIRELLRKGYKIELNGVSNHTKDKKSRVIFLDDIPDDTDDIKFTK
                     DIPSWKRMCYCILKNDHMCRFMGFGPTKEQRIRTEYIKKKYEKIH"
     gene            2312..2752
                     /locus_tag="PC466_002999"
     CDS             2312..2752
                     /locus_tag="PC466_002999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3788 domain-containing protein"
                     /protein_id="HDF2770361.1"
                     /translation="MYERMLDKSNKPCLSQIIEYIGKDGYARLCKLETYLETQYNLSR
                     ELRFPFGNNYGWGYKYSHKSFHLFYAFFEKGAFTVLIQIGDKQVPAVEKTLVSLTPKA
                     KELWVTRYTCGNNGGWIKYRILEDADLLDIIQYIRAKKSPPKQN"
     gene            complement(2937..3125)
                     /locus_tag="PC466_003000"
     CDS             complement(2937..3125)
                     /locus_tag="PC466_003000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770362.1"
                     /translation="MNKNNNLVIICMFIGMILGMAIGCAIGISKGNVGITMCYGLIFG
                     MIIGICIGTVIKNSNKKE"
     gene            4186..4581
                     /locus_tag="PC466_003001"
     CDS             4186..4581
                     /locus_tag="PC466_003001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770363.1"
                     /translation="MNILKMKKTGIFLGGVLFGTVGVKILSSDCVKKTCTRATAGALK
                     VKDSVLETTTKIQENVEDILAEAKEINEQEDLSTSKVNVVQDTLKCEQEVLKTETIKT
                     VEDTNSNNIKCEEIKDNVIEEKNNTCTTE"
     gene            4624..6723
                     /locus_tag="PC466_003002"
     CDS             4624..6723
                     /locus_tag="PC466_003002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HDF2770364.1"
                     /translation="MNFYIKHEIRGRIRFDLQLGKLNNKQSDTLLYYLTSINGITKAK
                     VYDRTGDAVIYYTGEREYIIREITKFSFNNSKIENLVPEHTSRELNNYYRDKLANKLL
                     VKSISKIFFPKSLRFFLIGLHSIKYFKKGLSSLLNKKIEISVLDATAIGISIFRKDIN
                     TAGSVMFLLGIGELLEEWTRKKSIDDLAQSMSLNIEKVWLKKDATEILVPISEIKEGD
                     LVSVTMGNMIPLDGVIVSGEAMVNQASLTGESLAVNKKEGSYIYAGTGIEQGNIVMCV
                     KEKAGTTRFQKIVTMIEESEKLKSSVESKFEHLADTLVPYSFLGSILTYAITRNPIKS
                     LSILMVDFSCALKLSIPISVLSAMRECNNHSIAVKGGKFLEGVACADTIVFDKTGTLT
                     KAQPTVSDIITFQNYNKKDMLRLAACLEEHFPHSIANAVVYEAEKQGLSHKEMHTEVE
                     YIIAHGISTKVDDKKVVIGSKHFVFEDEKCTIPDGEEDKYNNLSDEYSHLFMAISGKL
                     SAVICINDPLRKEAKYVISNLREYGIKKIVMMTGDSEKTAKSIASKVGVDEYYSEVLP
                     EDKANFVKSEKLKGRKVIMIGDGINDSPAISESDVGIAMSEGAEIAREISDITISADN
                     LNNLIVLKQISNKLMKRVDLSSKFIIGFNLGLILLGVSGFVRPSTSAFLHNASTVGIS
                     LNSMTNLLENTNTYNYY"
     gene            complement(6948..12158)
                     /locus_tag="PC466_003003"
     CDS             complement(6948..12158)
                     /locus_tag="PC466_003003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosome-binding GTPase"
                     /protein_id="HDF2770365.1"
                     /translation="MANKLYSEIVNLLEEGRDELRKYDLKEKSILLFLGASGVGKSTC
                     INYLKGCVMEEKTDEETGQIYITAKDSAVEIGNGVYSKTLCPEVVDIANRNFSLCDCP
                     GFFDNRGAEYMIAGAMLVRETISTSSKVKGMVVILDYQSLLDSRHTLLIETGKNLKDM
                     LGDYAKYKENFFFLINKIPKTLIGNVTEEKIRNILEKAKEDLDSQEKDYDGCKELVYL
                     LNVALSDGVSIKLCNPLDRQPEKLLDEMKNLPETFEKTDLGLMLTASCKIEIQKAVDV
                     TYKDLEKLLVPYIESVKKGMEDSISILSSINSLKDKKTQLDKMYTDLCSRTNNMKELM
                     EFVQELSYGDGVQKVNILEETRLLLELNSYCSETHIVGLSELLKSLLKNTLEDTLKDI
                     KYWIAEEEYREEEAKKLEDAEYRIEKIQSCTYIKSYEKENVLSIYIPIPKVNLSDLTK
                     IISGYQLNILSSIYMYGDCELKIDCNMEKEVFSGKNIVLLTEKLCIPEGIYSINVSGK
                     DAEKLVGEGSIYDGMNGRNGNNAGTSGDILLSFKEIEKRGELKLYVDGGRGGNGQDGK
                     RGDTGITGEAGENAKIGSKKESKEFAKVKGTKYYVVKAEKGKQGGTGGTGGNGGNAGL
                     GSKSGQVYLLGKASLLKGAISKKDGNHGLAGKGGSGGAGGAGGLGGIRGIYEETIRYI
                     GTSAPIDDSDRNYYYFDRYVFNHASNENQVADDGEKLNALYEKHKDWTISKREDSGLV
                     GAEGKDGRSGDALKEKELLKQEYSLSIDTFFYEFFERFGFSGIKGYRNLRLLCAVGIL
                     EADILELSHIYEIFHAVEKIEMQLNREILQKYYSFEKKNKAVLSLDDMNIKKEFYKEA
                     KEIYEYLINKLMQSDRIESFIGEKKNFSEWSMILFALEQKTAFYVQMIEESEIGGNRV
                     TDIRSLTDYLDKTLRELEQGKKDELKEGYFNTYKESILTQIESGNQQIEVLKDELENK
                     MLSVNAKMNLLIQEIIKMKEEEQEDIEELKKKQAKLEEQMKTQLILSGIQSALSLLTA
                     FSGVGQACLGAFDSAKSLKENLSAKEEEYQWTNRMVDFSDFKLDSDGMRFVLGEQLSE
                     DRKNALDKMTYNLAGVDEERRTKFDQIKEIIVKSIDDDNYAEKADDIQRAKEGLSESE
                     YKEIYTKIQKKEIGMLEANYNNKQQKDKLAALEKSKQAIERQQKTSKIKNALSIGSSA
                     CSLINTAISGVNNCLNVKSSFESKIEVVKEAIKDKENNIKKLDELNTQMVEFKDKTLK
                     ESVIPFVEKFDSTVKNQDIFENEISKLKMKEVLTELSTKFGSLKMENSEEISIIFKKV
                     QDMMETQIIITDKIDKKKDNLAMGELIYQMSGSGNQMNEYQKKLIHQIELNQVRYLCQ
                     VEAAAFQLWTFPFGSNIVNILNRCHVGITEDENEVINQAKEQNRQIREFLDQDAYQWQ
                     KTDNHILKVALTGSLDGKSRVGFENTYSLYDCNEEEVKKLLTGDEISFEVPLNKNFDA
                     IKYVTMYANIPNLRRNILEDSLKVKVHIHLYDSGYFSLYDDKKDVYYQYVFPQNYIDI
                     THGLDVKYNDSDSINSIWSSVEDKGIEKFKNAGLNSGRSPYSMAKISLKAHFNKKLSY
                     DSLTNEQKKKLESYFDKPSKYAWSESIDILKSLGYIDLKGILSKSWYEIKKDIDSDGE
                     IMKHFSILQVDLLERIIYEQTSILKENIPNLTIELVGCGIYVESEFNYLKQNDLKCYE
                     ERLVENTIIC"
     gene            complement(12173..14296)
                     /locus_tag="PC466_003004"
     CDS             complement(12173..14296)
                     /locus_tag="PC466_003004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF2770366.1"
                     /translation="MQNSVKQEPCDFSHGRFRPEADILDSRLTKVLDLFQQLNMCLHK
                     DNFRGSITFFISKSFLGRTEKQIYNVIKRKYEQLCENLDSNIEEKAWLFEELLKDNGK
                     NIHLCKPLESDEREGLLKQVLELDEVKDKTSAFQYPISADARLVLDTLIKEIQNNIVS
                     SLEDYVKAYTEDFISIIGSITMIQEIAKYDEVVKVFKNWLESTTTLTIERFINVLAKQ
                     SGLFLQDSCMELQNKIKGNLDIIDALSKYTEHGTGEILLPSVHMEFIIEKASKKIMEQ
                     NFIIIRKNLEKVLVSYEVQKQVFTLPNREKLMEVANKKDYVYSVSDFNSILTNVTVTQ
                     NEELEDSITRLSAYGEEGNEIIREFIGKYILNPFIVKTININDKKGIEIRALIPNLVI
                     SSVLEYFKNRKVDDNVSTFMFFAKDTIYMDDNLGMDFASEKNIILACNNLDVGSNVKI
                     NVSGKSGELVDSSMYGKNGEDGRDAGNIYLYIKEEIRNYRLTLIANGGNGSKGIDGKN
                     GETGDSGSNGADAGYTSSFHGQMFKGYFAKGTSGKKGDKGGAGGNAGRGGNAGNKGNI
                     YFISDSEEQKNRIINHCDITVKDGEAGPNGRPGSGGYGGSGGYHGYNTLSFSPSGIDK
                     TVYYTGYFTSWDYKLDSIIKYHIEFSGGSWNEGKTGPAREYAEYGDRGDDGGFNAPNT
                     KLSTAVSKVEENLIKEKYQGYCSEI"
     gene            complement(14361..>14888)
                     /locus_tag="PC466_003005"
     CDS             complement(14361..>14888)
                     /locus_tag="PC466_003005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDF2770367.1"
                     /translation="DFIENPKYLKKSLNKLAKLQRELSRKTIGSLNRNKARLKVARLQ
                     EHIANQRNDFLQKLSTKLIKENDIICIEDLQVKNMIKNRKLSRLISDVSWSEFIRQLK
                     YKANWHGRQIVKVGKFFASSQICNKCGYKNEEVKDLSIREWICPSCNETHDRDINASI
                     NILKEGLRLITIQNK"
BASE COUNT         4872 a         2707 c         1664 g         5645 t
ORIGIN      
        1 tttcctactc ttttttctgt gcttatatat aatattaaag ctctttattt tcaatatata
       61 ttttaaattt tctcttttta atatatcttt ttcttttaat aaatctcttt aattttcttc
      121 ttctatatca gagccaaagg gaatccatgc attaccaaac tctttatctt taaataaata
      181 agctaatcca gttatttgct tcaatctaag aatttcatca acttccatac ccaggtgctt
      241 tgatatccat tcatcagatt ttccaatttc acaaagttca gttataattt tactcattaa
      301 atccacatta tgagaacctc ttgcacgatt gtgtcgaata gtacttgcca ttctttcatc
      361 aagagattta tcaattactg aaacaggaag aagtccgttt tctctatcat atatatcctt
      421 attttcaagc attactctat atctatgaaa accatctaca ataatatact tatccttttc
      481 ctcattataa taacagacaa ttggcattgt atacccatct tcttttatac ttttatacaa
      541 caactgcatt tctggtgggg ctactgcatt tggattatag tcgttagatt ctatcttttc
      601 gattggcact gcgatgattc catatacagg acttttatat tccatagcat cttaactcct
      661 atctaatgaa ttttttcata tttcttctta atatattccg ttctaattct ctgttctttt
      721 gtaggaccaa atcccataaa tctacacata tggtcatttt ttaaaataca ataacacatt
      781 cttttccaac ttggtatatc tttggtaaat ttaatatcat ccgtatcatc aggtatatca
      841 tccaaaaata tgactctact ctttttatct tttgtatgat ttgaaactcc atttaattct
      901 attttataac cttttctcaa caattcacgt ataactattt ctgacaaacc accacctgta
      961 ttctgccaaa actcaataga tgttgaaaat tttttaatat agctattcct tatattttca
     1021 ggtaaggtat caagcaaaaa atatgtgaaa cttttccatg tgtgtccata tggcaattta
     1081 acactacgat atcccatagc ttttgttttt ccataaatag aagtaaaatt aactccttgt
     1141 actctagcaa ccaatttcac ccatacatct gggtccaata ttctgtataa atttaaactc
     1201 tcttttgctg aatcattaaa aggtgatgcc actctcattt ttcttggagc tactccagct
     1261 ttatagaata agtcataaat tttattatag tcataatcaa atttatagtg ggctaaccat
     1321 atatcttcta tttcccaatc atatatagga gatgccgtcc agacattttt aaattcctta
     1381 gttatccagc actttccttt atatccatgc tgtttattca caatagaaca ataacgttgt
     1441 agagattctg ctgctcgtgt tcctaataag caaacaactt ttgcaccttc atgtatatct
     1501 ctaatccatc taccaaattg ctttgccaaa ctttcttgtc tcattttata cttataataa
     1561 gtaaaaggat tatttttttg atttattatg tattctttga ctggcatttc tcttacccat
     1621 aattcttctt tctcatcatc ccatggatac caatacattt cataatttcc tacagcagtt
     1681 cttgtagcca ttggtaaaca cacccaatat ggttcaatat cttcaatatt ctcttcaaat
     1741 actttttcaa catattcagt agtcaaacta tattgagcct caaaatcttg atgaaatact
     1801 cctattttgg aacttatatt attctttctc ttataatcca aaactaaatt tagcagtaag
     1861 ccactatctt ttcctccact aaaagataca tagatataat caaattcatt aaaaagataa
     1921 gaaagtcttt cttgaaaagc ttcaaataca tcggattcta aatatctctt atccatttga
     1981 attatcccct ttcaattaga agtttataaa accttacaat acaatattat tatgcttttt
     2041 tagcagtaat cagcataaat tatacattat ttaaatacac aaatccaact aaacacatat
     2101 aattataatg taattatact tttgtattat aaactatatt ttatcattat tttacatttt
     2161 tttccaatat atataaatat catatttttc tattagctaa aaataattac tttatatttt
     2221 tacatgttag tataataaga cataaaaact tgacatactg ttgtcataat tactttgcta
     2281 taattaaaag taaaaatgga ggtaaattat aatgtatgaa cgtatgcttg ataaaagcaa
     2341 taaaccctgt ttgtctcaaa taatagaata tataggtaaa gatggatatg cacgattgtg
     2401 taagttggaa acttacttgg aaactcaata taatttatca agagaacttc gatttccttt
     2461 tggaaacaat tatggttggg gttacaaata tagccataaa tcttttcatt tattttatgc
     2521 tttttttgaa aaaggtgcat ttactgttct gattcagata ggtgacaagc aagttccagc
     2581 agtagaaaaa acgttggtat ctttgacacc aaaagctaaa gaactctggg tcactcgtta
     2641 tacttgtggc aataatggag gttggattaa gtatcgtatt ttagaagatg cagacttact
     2701 tgatattatt caatatataa gagcaaaaaa atctccacct aaacaaaatt aacttttatt
     2761 ttttgtgatt taaatatagt gtatataaat tccattcttt ccatattaaa aaaataatat
     2821 aaaaaatatc tattagtata tcttatttag tatgtcttat tctacttttt acagataatt
     2881 aaaaagtttt atcataaata aatcataact aaacatccta gtaaatcaaa attcatttat
     2941 tcttttttat tagaattttt gataacagtc cctatacata tgccaattat cattccaaaa
     3001 attagaccat aacacattgt gatacccaca tttcctttag aaatacctat agcacaacct
     3061 atagccattc caagtatcat gcctataaac atacatataa taactaaatt gttgttttta
     3121 ttcatagttt ttctccattc aatatatttt aaattgccta gctcgccttc ttagcttaaa
     3181 acaaagaaat ataaattaac tttctttcat tctaatatct gcttgtataa atgtcaaaca
     3241 acacatttct tgtcataacc tcctcttttt gaagtaagta caatctccca gacacaataa
     3301 tatcaatttc ctaaaaccat ttaagtaact tttatattta cataatattt acaatcataa
     3361 actatattgt tattcattta tacatcataa acactccctc ctaatcatta ttatacttaa
     3421 aataatgttc atttataata atatatctaa cgcactttaa ttgaaaaaac taaaactttg
     3481 cctttcattc ccatatataa ataagtatac tttttgatgc tctattacaa atcaactaaa
     3541 ttaattgata taaattatca ttttctgttg aaaataccat ttacacatgc tatacttaat
     3601 tgcataaatg gtaataaatg tcatatgatt ttacaaatct attaataaca attattactt
     3661 ttactgtatt ttaaagtttt tggactaaat atcaagaact ttctaaaata caaagtacaa
     3721 aaaatttata taagttataa atttatatga actagataag ctcaaacaat atgttatgta
     3781 taaactgtgt agtattcggt tataaattta tataaattat ataagctata taaagtatta
     3841 cctcaactat ataagctaga tatataaatt acatacataa gctagatata taaattgcat
     3901 atataagcta tataagaatt atttcaacta tataaactac atatataaat tacatacata
     3961 agctagatat ataaactaga tatataaact gcatatataa gctatataaa aattatttca
     4021 actatataaa ctacacatgt aaaattcatg taaatttact aatataaatc aaataaaatt
     4081 actaaactct ctaaactaat tttgtaaaac atactctatt tttaacattt gttaccttat
     4141 acataagtat aaacaaaatc taactaaatg aaaggataat gtaaaatgaa tattttaaaa
     4201 atgaaaaaaa caggaatatt tttaggagga gtactttttg gtactgtagg tgttaagata
     4261 ctttcaagtg actgtgtaaa aaaaacttgc actcgtgcaa cagcaggagc attgaaagtt
     4321 aaagattctg ttcttgaaac aactacgaaa attcaagaaa atgtagaaga tattttagct
     4381 gaagcaaaag aaatcaacga gcaagaagac ttatctacat ctaaggtaaa cgttgtacaa
     4441 gatactctta aatgcgaaca agaagttctt aaaactgaaa ctataaaaac tgtagaagat
     4501 actaattcta ataacattaa atgtgaagaa atcaaagata acgtaattga agaaaaaaat
     4561 aatacttgta caacagaata aatttaatga ttattatgat taataatatc aggaggaagt
     4621 aaattgaatt tttatataaa acacgaaata agaggtcgta tacgctttga cttacaactt
     4681 ggcaaattaa acaacaagca gtccgatact ctcttatatt atttaacttc tataaatggt
     4741 attaccaaag caaaagttta cgatagaact ggtgatgcag tcatttatta cactggtgaa
     4801 agagaataca taataagaga aatcactaaa ttcagtttta acaatagcaa aatagaaaac
     4861 ctagttcctg aacataccag cagggaatta aacaattatt atagagacaa attagcaaat
     4921 aaactgctag tcaaaagtat ctccaaaata ttttttccaa agtccttaag atttttttta
     4981 attggacttc attctataaa atattttaaa aaaggtctct cttccctact aaataaaaaa
     5041 atagaaattt ctgttttaga tgccactgct ataggtattt ctatttttag aaaagatatc
     5101 aatacggctg gttcagttat gtttcttctt ggtatcggtg agttattaga agaatggact
     5161 agaaaaaaat ctatagacga cttggctcaa agtatgtcac taaacattga aaaagtatgg
     5221 ttaaaaaaag atgccactga aatactagtt ccaatttcag agataaagga aggagattta
     5281 gtcagtgtaa ctatgggaaa tatgattcca ttggatggag ttatagtatc aggagaagca
     5341 atggtcaatc aggcatcact tacaggtgaa tcccttgcag ttaacaaaaa agaaggctct
     5401 tacatatatg ctggaactgg aatagagcaa ggcaatattg ttatgtgcgt caaggaaaaa
     5461 gctggtacta ctagattcca gaaaatagta actatgattg aagaatctga aaaactaaaa
     5521 tcttctgtag agagtaaatt tgaacatcta gcagatacat tagttccata cagcttttta
     5581 ggaagtatat taacctatgc aattactaga aaccctataa aatcactctc tatattgatg
     5641 gtagatttct cttgtgcatt aaaactctct atccctattt cagtactatc agccatgaga
     5701 gaatgtaaca atcacagcat tgctgtaaaa ggtggaaaat tccttgaagg tgttgcatgt
     5761 gcagatacta ttgtatttga taagacaggc acattaacaa aagctcaacc aactgtttca
     5821 gatataatta cattccaaaa ttataataag aaggatatgt taagacttgc agcttgctta
     5881 gaagaacact tcccacactc catagcaaat gcagtagttt atgaagctga aaaacaaggg
     5941 cttagtcaca aagaaatgca tacagaggta gaatatatta ttgctcatgg catttcaaca
     6001 aaggtcgatg ataaaaaggt tgtaataggt agcaaacatt ttgtatttga agatgagaag
     6061 tgtactatcc cagacggtga ggaggataag tacaacaatc tatcagatga gtattctcac
     6121 ctatttatgg caatatcggg taaattatca gcagttattt gcataaatga ccctttacga
     6181 aaagaagcaa aatatgtaat ttcaaattta agagaatatg gaataaaaaa gattgtgatg
     6241 atgactggag atagcgaaaa aacagctaaa tctatagcaa gtaaagttgg tgttgatgaa
     6301 tattattcag aagtcttacc agaagacaaa gccaattttg ttaaaagtga aaaactaaaa
     6361 ggtcgcaaag taattatgat tggtgatgga atcaatgatt ctcctgctat ttcagaatca
     6421 gatgtcggaa ttgcaatgag tgaaggtgct gaaatagcaa gagagatttc agatattacc
     6481 atatcagcag ataatttgaa taatttaatc gttttaaagc agattagtaa taagcttatg
     6541 aaaagagttg atttaagttc taagtttatt atcggcttta atttaggtct gattttactt
     6601 ggcgtaagtg gatttgttag accaagtaca tctgcctttt tacacaacgc atctactgtt
     6661 ggaataagtt taaacagtat gacaaattta ttggaaaaca ccaatactta taactactat
     6721 taatccccat tatataaaac atatgtatat aaaaaattta taattcatct tttaaaaaga
     6781 aactgtctta aaaggagctt ttttctaatc aaaattatat aaaacatatt ttacaaattt
     6841 taaactcaac ttatttctat tttttacaaa aaggagatga ttcaaatttt cattttgaaa
     6901 catccccttt tgtaaatttc tttaaaactt atatattaat tatattttca acaaataatt
     6961 gtattttcaa ccaatctttc ttcatagcat tttaaatcat tttgctttag ataattaaat
     7021 tcagactcta cataaatacc acagcctacc aattcaattg tcaaattagg tatattttcc
     7081 tttagtatac tagtctgctc ataaataatt ctttccaata aatcaacttg taatatagaa
     7141 aaatgcttca taatctcccc atcactatct atatctttct tgatttcata ccaactcttt
     7201 gacaaaattc ccttcaaatc aatataccct agactcttca atatatctat actctcgctc
     7261 catgcatact tactaggttt atcaaagtat gattctagtt tcttcttctg ctcatttgta
     7321 agtgaatcat aagaaagctt cttattaaaa tgtgccttca aagaaatctt agccatagaa
     7381 tatggacttc taccagagtt taatcctgca tttttgaact tttcaattcc tttatcttct
     7441 actgaagacc atattgagtt tattgaatct gaatcattgt atttaacatc aagaccatgt
     7501 gtaatatcta tatagttttg tggaaataca tattgataat agacatcttt tttatcatca
     7561 tatagggaga agtatccact atcatataaa tgaatatgca cctttacttt taaactatcc
     7621 tctaaaatat ttcgtctaag gttcgggata tttgcataca tggttacata ttttatggca
     7681 tcaaagtttt tatttaatgg aacttcaaaa ctaatttcat ctcctgtcaa aagctttttc
     7741 acttcttctt cattacaatc atatagagaa tatgtatttt caaatcccac acgtgatttc
     7801 ccatctaaac tgcctgttaa tgctaccttc aaaatatggt tatccgtttt ttgccattgg
     7861 taagcatctt ggtcaagaaa ctctctaatc tgtctatttt gctctttcgc ctgatttata
     7921 acctcgtttt catcttctgt aatacctaca tggcatctat ttaagatatt tactatattg
     7981 cttccaaatg gaaacgtcca tagttgaaaa gctgctgcct caacctgaca caaatatcta
     8041 acctgattta attcaatttg atggataagt tttttctgat attcattcat ctgattacca
     8101 ctacctgaca tttgataaat caattctccc attgcaagat tatctttttt cttatcaatc
     8161 ttatcagtaa tgataatttg agtttccatc atatcctgta cttttttaaa tattatagaa
     8221 atctcctctg aattttccat ttttaagctt ccaaactttg tgcttaattc agttaaaact
     8281 tccttcatct ttaatttact tatctcattt tcaaaaatat cttgattttt aactgtacta
     8341 tcgaattttt ctacaaatgg tataacagat tctttcaaag ttttatcttt aaattccacc
     8401 atttgagtat tcaattcatc taatttctta atattatttt ctttatcttt aattgcctct
     8461 ttaactacct ctattttact ctcaaaacta gattttacat taagacaatt attaacacca
     8521 ctaatcgcag tatttataag agaacaagca gaacttccaa tactcaatgc atttttaatt
     8581 ttagatgtct tttgctgtct ttcaatagct tgtttacttt tctctagtgc agctaactta
     8641 tctttttgct gtttattatt gtaatttgcc tccaacatac ctatttcttt tttctggatt
     8701 tttgtgtaaa tttccttata ctcgctttca cttaacccct cttttgctct ttgaatatcg
     8761 tcagcttttt ctgcatagtt atcatcatct atagacttaa ctataatctc cttaatttgg
     8821 tcaaatttag ttcttctttc ttcatcaaca cctgccaaat tataagtcat tttatctaaa
     8881 gcattttttc tatcttcact tagctgttct ccaagtacaa atctcatacc atcagaatcc
     8941 aatttaaaat ctgaaaaatc aaccatcctg ttagtccatt ggtattcctc ttctttagct
     9001 gaaagatttt ccttcaaaga ttttgcactg tcaaatgccc ctagacaagc ttgaccaaca
     9061 ccactaaatg cagtcagtaa actcaatgcg ctttgtattc cagaaagaat taactgtgtt
     9121 ttcatttgtt cctcaagttt tgcctgtttc ttttttagtt cctctatgtc ttcttgctcc
     9181 tcttctttca tctttataat ttcttgaatc aacaggttca tctttgcatt aacagaaagc
     9241 attttattct caagttcatc ttttaaaact tctatttgtt gatttccaga ttcaatttga
     9301 gttaggatac tttccttata agtattgaaa tatccttctt ttaactcatc tttctttcct
     9361 tgttccaatt ctcttaaggt cttgtccaga taatctgtca aagaacgaat atctgtaaca
     9421 cgatttcctc caatttcact ttcttcaatc atctgcacat agaatgctgt tttttgttca
     9481 agtgcaaata aaatcatact ccattcgcta aaattcttct tttctcctat aaaagattct
     9541 attctatcag actgcatcaa tttatttata aggtattcat agatttcctt tgcctcctta
     9601 taaaattctt tctttatatt catatcatcc agagaaagca ctgctttatt tttcttctca
     9661 aaactatagt acttctgaag tatttctcta tttaattgca tctctatttt ctcaactgca
     9721 tgaaaaattt cataaatatg tgaaagttct aaaatatcag cttctaaaat tcccactgca
     9781 cacaacagtc taagatttct ataaccttta attccagaaa aaccaaatct ctcgaaaaat
     9841 tcatagaaga aggtatctat tgacaaagaa tactcctgct ttaacaattc cttttctttt
     9901 aatgcatctc cagagcgacc gtcttttccc tctgctccga ctaaacctga atcttcacgt
     9961 ttgctaattg tccagtcctt atgtttttca taaagagcat ttaatttctc tccatcatct
    10021 gctacttggt tctcatttga agcatgatta aacacatatc tatcaaaata atagtaattt
    10081 ctatcactgt catctattgg agcagaggta cctatatatc ttattgtttc ttcatatata
    10141 cctctaattc caccaagacc tcctgcacca ccagctcctc cagagcctcc ttttcctgct
    10201 agaccatgat ttccatcttt tttacttata gcacctttta ataaagaagc ttttccaagg
    10261 agataaacct gtccagactt gctcccaaga cctgcatttc caccattacc tcctgtgcct
    10321 ccagttccac cttgttttcc tttttctgct tttaccacat agtattttgt acctttaacc
    10381 ttagcaaatt cttttgactc ttttttagaa cctattttag cattttcccc agcttctcca
    10441 gttatccctg tatctcctct ttttccatct tgtccatttc caccacgtcc accatctacg
    10501 taaagtttaa gttctcctct tttttctatt tctttaaaag ataataaaat atcacctgaa
    10561 gtacctgcat tattgccatt tcttccattc attccgtcgt aaatagaacc ttctccaacc
    10621 aatttttctg catccttacc agatacgttg attgaataaa tcccttctgg tatacataat
    10681 ttttctgtaa gtagtacaat attcttacct gagaagactt ctttctccat attacagtca
    10741 attttcaact cacaatctcc atacatatat atagatgaca aaatattaag ttgataacca
    10801 gatattattt tagtcaaatc cgataaattc actttaggta taggaatata tatagaaagt
    10861 acattttctt tctcatatga ttttatatat gtacaacttt gaatcttctc tatcctatac
    10921 tctgcatctt caagcttttt ggcttcttct tccctatatt cttcttctgc tatccaatat
    10981 ttgatatctt ttaatgtatc ttctaaagta ttttttagca atgattttaa caactcactt
    11041 agaccaacaa tatgagtctc actacagtag ctatttaact ctaaaagaag acgtgtttct
    11101 tctaatatat tcactttctg tacgccatca ccatatgaaa gttcttgtac aaactccata
    11161 agctctttca tattattagt cctactacat aaatctgtat acatcttatc taattgagtc
    11221 tttttatcct ttagactatt tatagaagat agaatggaaa tagaatcttc catacctttt
    11281 ttgacacttt ctatataagg aactaaaagt ttttctaggt ctttataggt tacatcaacg
    11341 gctttttgta tttctatttt acaagaagca gtaagcatca atcccaaatc tgttttttca
    11401 aatgtttcag gtagattttt catttcatcc aacaactttt ctggctgtct atctagtgga
    11461 ttacataatt taatagatac accatctgat aatgctacat ttaataagta cactaattcc
    11521 ttacaaccgt cgtaatcttt ctcttgacta tctaggtctt cttttgcttt ttccaatata
    11581 ttccttattt tttcttctgt tacattaccg attagtgttt taggtatttt attgataaga
    11641 aagaagaaat tttctttata ctttgcataa tcaccaagca tatctttcaa atttttgcct
    11701 gtttctatca ataatgtatg tctagagtcc agtaaggatt gatagtctaa aataactacc
    11761 atccctttca cctttgaaga tgtagaaata gtttccctta caagcatagc accagcaatc
    11821 atatactctg ctccacggtt atcaaaaaaa cctgggcaat cacataatga aaaatttcta
    11881 tttgcaatat ctacaacttc tggacataaa gtcttagaat atacaccatt tccaatttcg
    11941 acagctgaat cttttgcagt tatatatatt tgtccagtct cttcatccgt tttttcttcc
    12001 atcacgcaac cttttaaata atttatacaa gtactctttc caacgcctga agcacctaag
    12061 aataacaaaa ttgacttttc ttttaagtca tattttctaa gctcgtctct tccttcttcc
    12121 aaaaggttta cgatttcact ataaagttta tttgccatac atccatccct ttctatattt
    12181 cggaacaata gccttgatat ttttctttaa taagattctc ttctaccttt gaaacagctg
    12241 ttgataactt agtatttgga gcattaaatc ctccgtcgtc tcctctatct ccatattcag
    12301 cgtattctct tgctggtcct gttttgcctt cattccaact tccgccacta aattctatat
    12361 gatatttaat tatactatct aacttataat cccaacttgt aaaatatcct gtatagtaaa
    12421 cagtcttatc tataccactt ggagaaaatg aaagtgtatt atatccgtga tagccaccac
    12481 ttcctccata tccacctgaa cctggtctac catttggacc tgcttctcca tctttcactg
    12541 ttatatcaca atgattaatt attctatttt tttgttcctc tgagtctgaa atgaagtaaa
    12601 tattaccttt attaccagca tttccacctc ttccggcatt tccaccagct ccacctttgt
    12661 cacctttttt accacttgta ccttttgcaa aatacccttt aaacatctgt ccatggaaac
    12721 tacttgtata tcctgcatca gctccattac ttccagaatc tcctgtttca ccatttttac
    12781 catctattcc tttagaacca tttcctccat ttgcaatcag tgttaaacga taatttctaa
    12841 tttcttcttt aatatataag taaatattac ctgcatctct accatcttca ccatttttcc
    12901 catacataga actatctaca agttctccgc tctttccact tacattaatt tttacattac
    12961 tacctacatc aagattgtta caagcaagaa taatattttt ctctgatgca aagtccattc
    13021 caaggttatc atccatataa atagtatctt tggcaaagaa cataaatgta gaaacattgt
    13081 catctacttt tctatttttg aaatattcca atacactact aattactaag tttggaatta
    13141 atgctcttat ttcaatacct ttcttatcat taatattaat tgtttttact ataaatggat
    13201 ttaaaatgta tttaccaata aattctctaa ttatctcatt accttcttct ccatatgcac
    13261 ttaatcttgt tatactgtct tctaactctt cattttgtgt aactgtaaca tttgtcaaaa
    13321 ttgaattaaa atcacttaca ctatatacat aatccttttt atttgcaact tccattaatt
    13381 tttctctatt tggtaatgta aatacctgtt tttgtacttc ataagaaact aaaacttttt
    13441 ctaaattctt tcttattata atgaagtttt gttccattat cttcttactt gccttttcta
    13501 taataaattc catatgtaca gaaggtaata aaatttcccc agttccatgt tctgtatatt
    13561 tacttaaagc atcaattata tctaagtttc cttttatctt attttgtaat tccatgcaac
    13621 tatcttgtaa gaataagcca ctttgtttgg ctaatacgtt gataaatctc tctatagtaa
    13681 gagttgttgt actttccaac cagtttttaa atacttttac aacctcatca tattttgcta
    13741 tttcttgaat cattgttata cttccaataa tactgataaa atcttctgta tacgccttaa
    13801 cataatcttc taggctagat acgatattgt tttgaatttc ttttatcaac gtatctaaaa
    13861 ctaatcttgc atctgcacta attggatatt ggaatgctga tgtcttatct ttaacttcat
    13921 ctaattctag tacttgcttt aataagcctt ccctctcgtc tgattcaagt ggcttacaaa
    13981 gatgaatatt tttaccatta tcttttagca attcttcaaa taaccaagct ttttcctcta
    14041 tattactatc taaattttca cataattgtt catattttct ttttataaca ttatatattt
    14101 gtttttctgt tcttcctaag aaactttttg aaatgaaaaa agttatactg cccctaaaat
    14161 tgtctttatg aagacacata tttaactgtt gaaacaggtc tagtactttt gtaagtctag
    14221 aatctaatat atctgcttct ggtctgaacc tcccatgact aaagtcacag ggttcctgct
    14281 tcacagaatt ttgcatacta aaatatgtct tactaattct ccacaggcca tccccgtagt
    14341 tcctacggtt cttacataag ttatttattt tgaattgtta ttagtcttaa tccttctttt
    14401 aatatattta tacttgcatt tatatctcta tcgtgagttt cattacagct aggacaaatc
    14461 cattctctta tacttaagtc cttcacttcc tcgtttttat acccacattt attgcatatt
    14521 tgtgaacttg caaagaattt acctaccttt acaatttgtc taccatgcca attagccttg
    14581 tattttaatt gacgaataaa ttctgaccat gatacatcag aaattaagcg agatagttta
    14641 cgatttttaa tcatattctt tacttgtaaa tcttctatgc aaataatatc attctctttt
    14701 attaatttag tagatagttt ttgtagaaaa tcatttcttt gattggctat atgttcttga
    14761 agtcttgcaa cttttaatct tgctttattt ctatttaaac taccgattgt ttttctcgat
    14821 aattctcttt gtaatttagc aagtttgttt aatgacttct taagatactt aggattttct
    14881 ataaagtc
//
LOCUS       DAMJYN010000088        14786 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.092, whole genome shotgun sequence.
ACCESSION   DAMJYN010000088 DAMJYN010000000
VERSION     DAMJYN010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14786)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14786)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14786
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.092"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            825..2495
                     /locus_tag="PC466_003006"
     CDS             825..2495
                     /locus_tag="PC466_003006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF and EAL domain-containing protein"
                     /protein_id="HDF2770368.1"
                     /translation="MREESNSLSLDHIEIFFELLSQSTEDYIFFWDINRNKFKISSAI
                     FDEFNLSKEIESDLVNCWSKIVYPDDVQIWKDDIQELLHGKKGEHNLEYRLINKYEEI
                     VWISCRGKVYVSDDPKTIFLVGRIKNIGEKNKFDSITGTWNREQFEHRMNYLIKEKIY
                     KNGAMFIMDIDNFKNINEKYGHSYGDKVLRAIATEVLEYLPKDVRLYRLDGDEFAFFY
                     PMCTKETIEKIYEKIQMYTNTQHEIESNKYYCTVTAGVAMYPEDGDNYLDLFKHADIA
                     LDIAKISGKNRIKFFSQELYENKLKVISMQQKLRECVENNFNDFELFFQPQVNAVTKE
                     VIGAEVLLRWHSSTYGEVSPVEFIPILEQSNLIIPVGKWIIKEAVKQCKEWHKINPDF
                     KISVNVSYIQLKEDFFRDFIVECLVEYQLRPEFLILELTENCWIPDINLLNDKFISLK
                     GIGVYIAIDDFGTGYSSLNYLKELSVNIIKIERSFVKNITYNSYEYTFLEYIIKLAHI
                     INLKVCVEGIESYEEYDIVKSLGVDIIQGFLFGRPVSASEFYKFQLSK"
     gene            complement(2617..3351)
                     /gene="pflA"
                     /locus_tag="PC466_003007"
     CDS             complement(2617..3351)
                     /gene="pflA"
                     /locus_tag="PC466_003007"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HDF2770369.1"
                     /translation="MIKGKIHSIETFGTVDGPGIRYILFFQGCPLRCKYCHNRDTWDI
                     KSGKEYTVDEIITDALKYTSFMKFSGGGITASGGESTLQPEFLSELFKKAKENDIHTC
                     LDTSGFVDIETIDPVLDNTDLVLLDLKHMVEEKSIDLTGVGMDKALKLARHLESRNIP
                     VWIRHVLVPGITDDIDNLEKLGQFVATLKNVERFELLPYHSMGIHKWESLGIDYELKD
                     VPDATKEDVQKASEIISKFGVKVYNS"
     gene            complement(3511..5742)
                     /gene="pflB"
                     /locus_tag="PC466_003008"
     CDS             complement(3511..5742)
                     /gene="pflB"
                     /locus_tag="PC466_003008"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HDF2770370.1"
                     /translation="MNAWQGFKTGRWTKEINVREFIQLNYSPYEGNDSFLAGATENTK
                     KLWDEAMVLFKKERENGGTLDVDTKTVSGIAAYAPGYLDKELETIVGLQTDAPLKRAV
                     MPYGGIKMVENSCEAFGYELDPEIKDIFTKYRKTHNQGVFDVYTPEMRAARKSGIITG
                     LPDAYGRGRIIGDYRRVALYGVDALIEDKNEQKKSLEVSCMDEEVIRLREEITEQISA
                     LNELKKMAESYGFDISKPATNSKEAVQWLYFGYLGAVKDQNGAAMSLGRTSTFLDIYF
                     ERDLKAGIVTEEELQEYMDHFVMKLRMVKFLRTPDYNNLFSGDPTWVTECIGGMGIDG
                     RTLVTKNSFRMLNTLYTLGPSPEPNLTVLWSTKLPQGFKDFCSKVSIDTSSVQYENDD
                     LMRAYWGDDYGIACCVSAMRIGKQMQFFGARVNLAKTLLYAINGGVDEKSGVQVGPRF
                     EPITSEYLDYDEVMSKFEPFTDWLATLYVNTLNVIHYMHDKYSYEALEMALHDRDIFR
                     TMACGMAGLSVCADSLSAIKHAKVKTIRNEQGIAVDFEIEGDYPKYGNNDDRVDSIAV
                     ELVESFMNKIRKNKTYRNSYPTQSILTITSNVVYGKKTGNTPDGRRAGAPFAPGANPM
                     HGRDTNGALASLSSVAKLPYEHAQDGISNTFSIVPAALGKDMTERINNLSAMMDGYFS
                     QNAHHLNVNVFDRATLEDAMEHPEEYPQLTIRVSGYAVNFIKLTKEQQLDVINRTFHG
                     KMA"
     gene            6035..7096
                     /locus_tag="PC466_003009"
     CDS             6035..7096
                     /locus_tag="PC466_003009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium/sodium antiporter"
                     /protein_id="HDF2770371.1"
                     /translation="MEKRKSIHLHKLNIYLIGGGDRLFITVVLFLVGFLLITKGADIF
                     INCTVEIGRKTNISEIILGATIVSFATTLPEFTVSLLASIDGHTTMSLGNAVGSIICN
                     TGLALGLVVFISPFNVDKKMFFSKSLLLIVSVIVLILLSLDGVITRGDSLLLIIILIF
                     YMVNNYRSVVGKSDTKNRNIKNNTIKDISTKKGKNYRGFSVLEIVKILLLFATGLIMM
                     IIGSQILIESGVIIASFLNIPQGIVSLTIIALGTSLPEIVSSITAIRKNHHEISVGNI
                     LGANILNIVSVIAVSAIPNNIPILSQNRQLDIPFMILLLLIVIIPTLKSNRLSRIQGI
                     LMLFTYFLYISILYFMYII"
     gene            7187..8800
                     /locus_tag="PC466_003010"
     CDS             7187..8800
                     /locus_tag="PC466_003010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HDF2770372.1"
                     /translation="MNITKFEDLPISEGIKKAIAEMGFEEPSPIQAQSIPAILSGKDV
                     IGQAQTGTGKTAAFSIPILETIDPNNRSLQAVVLCPTRELAIQVSTEIRKLAKYSHGI
                     KTLPIYGGQPIDRQIKSLKSGVQVVIGTPGRTIDHINRKTLKMDNVKMIILDEADEML
                     DMGFREDIEMILSKIPEERQTTFFSATMPRGILELTKRYQKDPEHIKVVRKELTVSNT
                     KQYYIETRSSNKLEVLCRLVDVYDPKLSVVFCNTKRKADELVGDLQARGYFADALHGD
                     LKQTQRDIVMDKFRNGTIDILVATDVAARGIDVDDVECVFNYDLPQDEEYYVHRIGRT
                     GRAGREGMSFTFVFGKEMRKMKDIERYTKSKLIKHNIPTITDVEEKKVGTFFAQVKQT
                     IEEGHLTKQLQWLEGFCNDEDYAMVDIAAALVKLSLGEEMKEEIIEEKPRRERGDRKG
                     GTGAKDGMIRLFINIGRNQRVQAKDIVGAIAGEVGIPGKVVGTIDIYDKYTFVEIPKK
                     DAKTVIEKMKDIKIKGNKINIEKANKKKK"
     gene            9075..11060
                     /locus_tag="PC466_003011"
     CDS             9075..11060
                     /locus_tag="PC466_003011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HDF2770373.1"
                     /translation="MSMTYMDPRVFLILEMVLEEDTNTLEQFSNVLGVSTRTIRNYIN
                     QINRELKGGIAKIVKNEKGTYSIRIEDESKLIEIVNFNRGKLSNFINLNSPDERINYV
                     LDILTMTNNPITIDDLAEEICIGRTTLIKDLKKADRILAEYDLELKRKPNIGMILVGE
                     EMDIRLLILDRLYENYIDVLENVNQINLVKDYDIECLRDELKKLFKKEELYITEQVLR
                     DVERYIIMSVLRNLNGYKFEKIDKRFEVIRCSDEYTLGLKLKALLEKIFNIVLNEKET
                     IFLTMPLIGRKAPSTKLALSSIKINDSVKEVVDEVTSFLLETSGIDFKEDKKLIENLE
                     YHLYFALNRMRFNIRVKNPLLQEIKERYTFPYSVAKIAAMIIEEKFDLKICDHEIGYI
                     ALHFGSYFEKNSRKVLNVNRVAVVCGTGLGTAQLIRIKIGKILGESVEVNTFSDIEAK
                     ANLDLLKYYDLVFTTVDFKTDLDVPIFRVNALFNEESIKKEIENAILLKNSINLKSIK
                     KIEKNIPFIGKLIEEDKFFILNKSTFMENLEDMLEKLVHKGIIDIEFKKKVLKREKKS
                     STALDNYIALPHSVNTNGENLYLSFGILEKPVVWDTKEIRIIILMIIPDKNVDSTDLI
                     IKSYEEVLEVGRDKKMIEELAKVKSFDEFYKIITKRR"
     gene            11065..11499
                     /locus_tag="PC466_003012"
     CDS             11065..11499
                     /locus_tag="PC466_003012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator GutM"
                     /protein_id="HDF2770374.1"
                     /translation="MDPVIFIIASLITVYLLNIFLGYLQLKDFNKNYIELKRKGRVAI
                     GRKKGRISSGTIVLILINDDGVIVETRKMQGVTVLARVKSFEGLVGKSLEYIEKSDLT
                     VYNKLLKKAILDAVKQYITFEKNKCEDTNNLSTDEECRMEVV"
     gene            11528..12088
                     /gene="srlA"
                     /locus_tag="PC466_003013"
     CDS             11528..12088
                     /gene="srlA"
                     /locus_tag="PC466_003013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418408.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HDF2770375.1"
                     /translation="MTQFFQVLASGADSFMNLFRAGGQQFVGFVTDIVPLLVALLVTM
                     NAIINFIGTDRVERLAKKCSANIFTRYLILPVLGTFVFANPMTLSLGRFLPEKFKPSY
                     FAAASFSCHTMNGLFPHINPGELFIYLGIANGITTLGFSTADLAVRYLLVGIVANFIK
                     GVVTDYTTKFVEKQQGIALNSDIKIG"
     gene            12152..12520
                     /locus_tag="PC466_003014"
     CDS             12152..12520
                     /locus_tag="PC466_003014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sorbose transporter subunit IIB"
                     /protein_id="HDF2770376.1"
                     /translation="MAFNKVKIVKGSGGWGGPLIIEPTEKKNKVVYVTGGAKPETAVK
                     IAELTGCELIDGFSQGVKDDEIACVIINCGGTLRCGIYPQKKIPTINIMKTGKSGPLA
                     MFIKEDIYVSGVKPTNVEQL"
     gene            12545..13111
                     /locus_tag="PC466_003015"
     CDS             12545..13111
                     /locus_tag="PC466_003015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003374365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HDF2770377.1"
                     /translation="MAYDTKKKISEQSQGIVAKIGIALGNVTSTLFQAGRDTIDTLIH
                     TILPFMAFVAVLIGIINQSGIGNWVANLLTPLIGNVGGLVVLSIICSFPLLSPFLGPG
                     AVIAQIVGVLVGTEIGKGNIPPSLALPALFAINSQAACDFIPVGLGLAEAEPDTVQVG
                     VPSVLYSRFLTGAPTVLLAWLASFGLYK"
     gene            13152..13517
                     /locus_tag="PC466_003016"
     CDS             13152..13517
                     /locus_tag="PC466_003016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HDF2770378.1"
                     /translation="MELIYSTQINKIGDNANEFLQHNMFVTFKDNAPQELENYCYIHS
                     ENNLVKEILTNDVLSINNVDYKITSVGELVNQNLSELGHITFKFTGEKDGAIGGTLYL
                     EEKEIAPIGVGTILKIIRK"
     gene            13618..14391
                     /gene="srlD"
                     /locus_tag="PC466_003017"
     CDS             13618..14391
                     /gene="srlD"
                     /locus_tag="PC466_003017"
                     /EC_number="1.1.1.140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sorbitol-6-phosphate dehydrogenase"
                     /protein_id="HDF2770379.1"
                     /translation="MRKVALVVGGGRSLGEYLSKHLAKVGYDVAIADLNEDNAKKVAE
                     EIETEFGCKSVGYGCNAIDERQVISTVKAIENDFDRIDLLVYNAGVAVSKKITDFGYK
                     DFKFIVDVNLNGYFLFAREVSKVMIAKGIEGRIIQINSKSGRVGSKHNSGYSAGKFAG
                     VGLTQSLALDLAEHKITVNALMLGNLLDSDMFESLIPQYAVKLGIPESEVKQVYIDKV
                     PLKRGCRFIDVANMLTFYASKEAEYCTGQSINITGGQVM"
BASE COUNT         5676 a         1752 c         2480 g         4878 t
ORIGIN      
        1 aattaaaata aaaaatatta ttttatattt ataaacattg acattctaat tctgtagtgt
       61 aatcgtattt tttattaatt cttataaaat caatgaaaat aaggatatcc attttaaagt
      121 acataaattt aaaaatccag aaaaatatac ttaaattatg taagcaaaag aggggttgaa
      181 tcggctgaaa atgtaatact agtaaatagt acatcaatcc tagataccct gtaagcaact
      241 ctattttcat gtactaaaaa tgtacctatt ttattaactg aaaagaataa attaaatgta
      301 agtacataat aagagataaa aaattaaaag caaaaaatat ttatataaat aaatataaaa
      361 aatgatataa tccctattaa aaaatttata gatgatgaag aaatatcaaa atcttatatt
      421 ataggaagag gcacttcttt gccaaaatat atagaaaagc aataccaaat ccaaagagaa
      481 taggctgaga aaaaataaaa caaattcaag agtaatagaa aagctttata gaataaagaa
      541 ctgagaactc tttatataat aaaaaatgga cttttaagag aaaatgattt aataaatgat
      601 ttaacatggt gttttagcag gtgaaaataa atcaccagta atgattgtag aaaaattact
      661 ttatgaatct caaaaaaact tagttaagag taagagattt gataagataa ctaaagttgg
      721 ggaaatgtgt ttgatgagat aaaaaaatta gtaaaatagt ataatctaaa taagaatatt
      781 ttgttgatta aactacacta atagtaatat tgtaggggga aaagatgaga gaagaatcga
      841 actctttaag tttagaccat atagaaattt tctttgaact tttatctcaa agtacagaag
      901 attatatatt tttttgggat ataaatagga ataaatttaa aatttcttca gcaatttttg
      961 atgaatttaa cttaagtaaa gagatagaat ctgatttagt caattgttgg agtaaaattg
     1021 tttatccgga tgatgttcaa atatggaaag atgatataca agaattacta catggaaaaa
     1081 aaggtgagca caatttagaa tataggttga ttaataaata tgaagaaata gtatggattt
     1141 cttgtagagg taaagtttat gtgtcggatg acccaaaaac tatatttcta gtcgggagaa
     1201 taaagaatat tggtgaaaaa aataaatttg attctatcac aggaacgtgg aatagagaac
     1261 aatttgaaca tagaatgaat tatcttataa aagagaaaat ttataaaaat ggtgctatgt
     1321 ttatcatgga tattgataat tttaaaaata taaatgaaaa atatggacat tcttatggtg
     1381 acaaagtatt gcgtgcaatt gctactgaag tattagaata tcttccaaaa gatgtaagat
     1441 tgtataggtt agatggagat gaatttgcat ttttttaccc tatgtgtact aaagaaacta
     1501 tagagaaaat atatgaaaag atacagatgt atacaaatac tcagcatgaa attgaatcaa
     1561 ataagtacta ttgcacagtg actgcaggag ttgctatgta tccagaagat ggagataatt
     1621 atttagattt atttaaacat gctgatattg cattggatat agcaaaaatt agtggtaaaa
     1681 atagaattaa gtttttttca caagagctct atgaaaataa actaaaggta atttcaatgc
     1741 aacaaaaact aagagagtgc gttgaaaata attttaatga ctttgagctg ttttttcaac
     1801 cccaggtaaa tgctgttaca aaagaggtaa taggggcaga ggtactttta agatggcatt
     1861 cgagtactta tggagaagta tctcctgttg aatttatacc aatactagaa cagagtaatt
     1921 taattatacc agttgggaag tggattataa aagaagctgt aaaacagtgt aaagaatggc
     1981 ataaaataaa tccagacttt aaaatatctg taaatgtatc gtatattcag ttaaaagaag
     2041 atttttttag agattttata gtagaatgtt tagtagagta tcaattaaga cctgaatttt
     2101 taattttgga attaacagag aattgttgga taccagatat aaatttacta aatgataaat
     2161 ttattagttt aaagggtata ggagtatata ttgcaataga tgactttggt acagggtatt
     2221 catctttaaa ttaccttaaa gaactgtctg ttaatataat aaaaattgaa agaagttttg
     2281 ttaagaatat tacatataat agttatgaat atacttttct tgaatatatt attaaattag
     2341 ctcatattat aaatttaaaa gtttgtgttg agggaataga gtcttatgaa gagtatgata
     2401 tagtaaaaag cttaggtgta gatattattc agggtttttt atttggaaga cctgtaagtg
     2461 cctctgaatt ttataaattt caactatcaa agtgatgtac ataaaatgag atatatagta
     2521 tataaaaata gggcaaagtg gaagttttga agtttattaa aaatttacac tttaccctat
     2581 tttgttatgt cttctataaa ggattaatat actacactaa ctattatata ctttcactcc
     2641 aaatttagag attatttcac tagctttttg gacatcttcc ttagtggcat caggaacatc
     2701 ttttagttca taatcgatac ctaaactttc ccatttgtgt attcccatag aatggtatgg
     2761 tagcaattca aatctttcta catttttcaa tgtagctaca aattgaccta gtttttctaa
     2821 attatctata tcatcagtaa tgccaggaac taaaacatgt cttatccata caggaatatt
     2881 tcttgattct aagtgtctag caagttttaa tgccttatcc ataccaacac cagtcaaatc
     2941 aatagatttt tcctcaacca tatgttttaa atcaagtaaa accaaatcag tattatctaa
     3001 aactgggtct atagtttcta tatctacgaa tccagatgta tccaagcaag tgtgtatatc
     3061 attttctttt gcttttttaa ataattcact taaaaattct ggttgaagag tggattcacc
     3121 accagaggca gttatacctc caccagaaaa cttcataaaa gaagtatact taagagcatc
     3181 cgttattatt tcatcaactg tgtattcttt tcctgattta atatcccatg tatccctgtt
     3241 atgacagtat ttgcatctaa gaggacaccc ctgaaaaaat aatatatatc ttattcctgg
     3301 tccatctaca gtaccaaacg tttctataga atgtatcttt cccttaatca tagagttcac
     3361 ctcacaatat attttaataa ccttatcaat agttataata tttgtctaaa aaaggccatc
     3421 ttataccaga aataattcaa atataagata gccttttatt tttatttttt acacagtagt
     3481 aatcttagtt aaagtataaa aatttaaaga ctaagccatt ttaccgtgga atgttctgtt
     3541 tataacatct aattgttgct ctttagttaa ttttatgaag ttaactgcat atccagatac
     3601 tcttatagtt aattgtggat attcttctgg atgttccata gcatcttcta aagtagctct
     3661 atcaaataca tttacattta agtgatgagc attttgagag aagtatccat ccatcattgc
     3721 agaaagattg tttattcttt cagtcatatc ttttcctaaa gcagcaggta ctatagagaa
     3781 agtattagat ataccatctt gagcatgttc atatggtaat ttagcaactg aagataatga
     3841 agctaaagca ccattagtat ctctaccatg cattgggtta gcaccaggag caaatggagc
     3901 accagctctt ctaccatctg gtgtattacc agttttctta ccataaacaa catttgaagt
     3961 tattgtaagt atagattgag ttggataaga atttctataa gttttatttt ttcttatttt
     4021 attcataaag ctttcaacta actctacagc tatactatca actctatcat cattgtttcc
     4081 gtattttgga taatctcctt ctatttcaaa atcaacagct attccttgtt catttctaat
     4141 agttttaacc ttagcatgtt ttatagcaga taatgagtct gcacaaactg ataacccagc
     4201 cataccacaa gccatagttc taaatatatc tctatcatgt aatgccattt ctaatgcttc
     4261 ataagaatat ttatcatgca tataatgtat tacatttaaa gtatttacat ataatgttgc
     4321 taaccaatca gtgaatggtt caaatttact cataacttca tcataatcta agtactcaga
     4381 agttataggt tcaaatcttg gtccaacttg aacaccagat ttctcatcta caccaccatt
     4441 tatagcgtat aataaagttt tagctaagtt aactctagct ccaaagaact gcatttgttt
     4501 accaattctc attgcagata cacaacaagc tataccatag tcatctcccc agtatgctct
     4561 cattaaatca tcattttcat actgtactga acttgtatct atagatactt tagaacagaa
     4621 atctttgaat ccttgaggta atttagttga ccatagaact gttaagtttg gctctggaga
     4681 aggtcctaat gtatatagag tatttaacat tctaaatgag tttttagtaa ctaatgttct
     4741 accatctatt cccatacctc ctatacactc agttacccaa gttgggtctc cagagaatag
     4801 gttattgtaa tcaggagttc ttaggaactt aaccattctt aatttcataa caaaatggtc
     4861 catatactct tgtaattctt cttctgttac gattccagct tttaaatctc tttcaaagta
     4921 tatatctaag aaagtagatg ttctacctaa agacattgca gcaccatttt ggtctttaac
     4981 agcacctaaa taaccaaagt ataaccattg tacagcttct tttgagttag ttgctggttt
     5041 tgatatatca aatccataag attcagccat ttttttaagt tcatttaaag ctgatatttg
     5101 ctcagttatt tcttctctta atctgataac ttcctcatcc atgcaagaaa cttctaatga
     5161 tttcttttgc tcatttttat cttctattaa agcatcaaca ccgtatagag caactcttct
     5221 gtagtcacca attattctac ctctaccata agcatctgga agacctgtta ttataccaga
     5281 ttttctagca gctctcattt ctggagtata aacatcaaaa actccttggt tgtgtgtttt
     5341 tctgtattta gtaaatatat cttttatttc tgggtctaat tcatatccaa aagcttcgca
     5401 tgaattttca accatcttta taccaccata tggcatgaca gctcttttta aaggggcatc
     5461 cgtttgtaac ccaactattg tttctaattc tttatctaaa tatcctggag catatgcagc
     5521 tattccagaa acagtttttg tatcaacatc taaagtacca ccattttctc tttctttttt
     5581 aaataggacc attgcttcgt cccataattt tttagtattt tcagtggcac cagctaagaa
     5641 agagtcattt ccctcatatg gagaatagtt taattgtata aactctctaa catttatttc
     5701 tttagtccat cttcctgttt taaatccttg ccatgcattc attaagtatt tcctccttag
     5761 atttaaatga taaataatac tattaaaatt attttttata tacttaattt attttatata
     5821 tttttttaaa aatatatttt ctaatataat aatatcatat tattcgtatc ctgtatacat
     5881 aaaaaataaa aaattgtcgc tttaaagtat aaaacagatt atatgttaat aatgtggtga
     5941 aattataccc atatataaat aaaataaaac aaataaatag ctaattaggg agaaaatatt
     6001 ttttattttt tgtttaggat aaataaattt tattatggaa aaaagaaaaa gcatacatct
     6061 tcacaaattg aatatttatt taataggggg aggtgataga ttgtttatca cagtggtatt
     6121 atttttagta ggtttcctat taattactaa aggcgcagat atctttataa attgcactgt
     6181 agagataggt agaaaaacga atatatcaga aattatactt ggagctacta tagttagttt
     6241 tgcaacaaca ttacctgaat ttacagtgtc tctacttgct tctattgatg gtcatactac
     6301 tatgagttta ggaaatgcag ttggttctat aatatgtaat acaggattag cattagggtt
     6361 ggttgttttt ataagtccat ttaatgtaga taaaaaaatg tttttttcta agtctttact
     6421 attaatagta tccgttatag ttttaatttt attgagttta gatggagtta taacaagagg
     6481 tgattcatta ttacttataa taatattaat cttttatatg gttaataatt atagaagtgt
     6541 cgttggaaaa tctgatacta aaaatagaaa tattaaaaat aacactatta aagacatatc
     6601 tactaaaaaa gggaaaaatt atagaggttt ttccgtatta gaaattgtaa aaatactatt
     6661 actttttgct acaggattga taatgatgat aataggttca caaatcctta tagagagtgg
     6721 agtaataata gctagttttt taaatatacc tcagggtata gtaagtttaa ctataatagc
     6781 acttggaact tctctgccag agatagtttc gtcgattact gctataagaa aaaatcatca
     6841 tgaaatatca gtaggaaata ttttgggtgc aaacatattg aatatagtat cagtaatagc
     6901 tgtatcagca ataccaaata acataccaat actatctcaa aatagacaat tggatatacc
     6961 attcatgata ttattattat taatagtaat aataccaaca cttaaatcta atagacttag
     7021 tagaatacaa ggtatattga tgttattcac atattttctg tacatatcaa ttttgtattt
     7081 catgtatatt atttaactat actgtttaaa atattaattg cagaatatcc taaaaaagta
     7141 tataatggat aggttaagat taattgataa cggagaggaa taatatatga atataacaaa
     7201 gtttgaagat ttaccaataa gtgagggaat aaaaaaagct atagctgaaa tggggtttga
     7261 agaaccatct cctatacaag cacagtctat acctgcgatt ttgtcaggta aagacgttat
     7321 aggacaagct caaactggta cgggaaaaac agctgctttt agtatcccta tactagaaac
     7381 aatagaccca aataatagaa gtttacaagc tgtagtgctt tgtccaacaa gagaactggc
     7441 aatacaagta tcaacagaaa taagaaagtt agctaagtat tcgcacggaa taaagacatt
     7501 acctatatat ggtggccagc caatagatag acaaataaaa tctctaaaga gtggtgtgca
     7561 agttgtaata ggtacaccag gacgtacaat agaccatatc aatcgtaaaa cattaaagat
     7621 ggataatgta aaaatgatta tattagatga agcagatgaa atgctagata tgggatttag
     7681 agaagatata gaaatgattt taagtaagat tccagaagaa agacaaacaa ctttcttttc
     7741 agctactatg ccaagaggaa ttttggaatt aactaagaga tatcaaaaag acccagagca
     7801 tataaaagtt gttagaaaag aacttacagt ttcaaataca aagcaatact atatagaaac
     7861 taggtcatca aataaattag aagtattatg tagattagta gatgtatatg accctaaact
     7921 atctgttgtt ttctgtaata ctaagagaaa agcagatgaa ttggtaggag atttacaagc
     7981 aagaggatat tttgcagatg cattacatgg tgacttaaaa cagactcaaa gagatatagt
     8041 aatggataag tttagaaatg gtacaataga tatacttgtt gctactgatg ttgcagctag
     8101 aggtatagat gttgatgatg ttgaatgtgt attcaactat gacttaccac aagatgaaga
     8161 gtattacgtt catagaattg gtagaactgg tcgtgctggt agagaaggta tgtcatttac
     8221 ttttgtattt ggaaaagaaa tgagaaagat gaaagatata gaaagatata ctaaatctaa
     8281 actaataaag cataatatac caacaataac tgatgttgaa gagaaaaaag taggtacttt
     8341 ctttgcacaa gttaaacaaa ctatagaaga aggtcactta actaaacaat tacaatggtt
     8401 agaaggtttc tgtaatgatg aagattatgc aatggttgat atagctgctg cacttgtaaa
     8461 actatctcta ggtgaagaaa tgaaagaaga aataatagaa gaaaaaccta gaagagagcg
     8521 tggagataga aaaggtggta ctggagctaa agatggtatg attagattat ttatcaatat
     8581 tggtagaaat caaagagtac aagcaaaaga tatagttggt gctatagctg gagaagttgg
     8641 aataccaggt aaagtagtag gtactataga tatatatgat aagtatactt ttgttgaaat
     8701 acctaaaaaa gatgcaaaaa cagtaattga aaagatgaaa gatattaaga taaaaggtaa
     8761 taagattaat atagaaaaag caaataagaa gaaaaaataa cgtatagtat acaaaactat
     8821 aattagaaaa tatataaaat aatatattgg atatttaaaa agcctgatgt gttttcaaaa
     8881 cagatagtag ataatctgta agagttaaca gcataaggct tttcttgttt tatatgatat
     8941 tatgattttc cagatcgttg tgaaaaatgt atattagttc ctttttttca aatctgattt
     9001 gaaaaagaga atattaatta tctatatagt ttagattata ataaaaaatg taagataaca
     9061 aaggggagaa aaagatgtca atgacttata tggaccctag ggtttttttg attttagaaa
     9121 tggtgttaga agaagacaca aatactctag aacaattttc aaatgttttg ggtgttagta
     9181 ctaggactat cagaaactat ataaaccaga ttaatcgaga attaaaaggt ggtattgcta
     9241 aaatagttaa aaatgaaaaa ggtacatata gtataagaat tgaggatgaa agtaaattaa
     9301 ttgagattgt aaattttaat agaggaaagc tatcaaattt tataaattta aattcacctg
     9361 atgaaagaat aaattatgtt cttgatattt taactatgac caacaatcca attaccatag
     9421 atgatttggc tgaagagata tgtataggaa gaacaacatt aataaaggat ttaaaaaaag
     9481 cagacagaat tttagctgaa tatgatttag aattaaaaag gaagccaaat ataggtatga
     9541 ttttagttgg tgaagaaatg gatataagat tattaatcct tgatagattg tatgaaaatt
     9601 atattgatgt cttggaaaac gttaatcaga taaatttagt taaagattat gatattgaat
     9661 gtcttagaga tgaattaaaa aagttgttta aaaaagaaga actctacata acagaacagg
     9721 tcttgagaga tgttgaaaga tatataatca tgtctgtctt aagaaatcta aatgggtaca
     9781 aatttgaaaa gatagataag agatttgaag tgataagatg ttcagatgaa tatactttag
     9841 gattaaagct caaagcttta ttggaaaaga tatttaatat agttttaaat gaaaaagaaa
     9901 ccatattttt gacaatgcca ttaataggta gaaaagctcc tagtacaaaa ttagcactta
     9961 gcagtataaa gataaatgat agcgtaaagg aagttgtaga tgaagtaact agttttttat
    10021 tagagacctc agggattgat tttaaagaag ataaaaagct tatagaaaat ttggaatatc
    10081 acttgtattt tgcacttaat agaatgagat tcaacataag ggtaaaaaat cctcttttac
    10141 aagaaataaa ggaaagatat acatttccat atagtgttgc aaagatagct gcaatgataa
    10201 ttgaggaaaa gtttgacttg aaaatatgtg accacgaaat aggatatata gcattacatt
    10261 ttggaagtta ttttgaaaaa aattcaagaa aagttctaaa tgtaaatagg gtagctgttg
    10321 tttgtggaac aggtcttggg actgcacaac ttattagaat aaagatagga aaaatacttg
    10381 gagaaagtgt agaagtaaat actttttctg atatagaagc taaagctaat ttagatttat
    10441 taaagtatta tgatttagta tttacaacag tagatttcaa aacagactta gatgttccaa
    10501 tttttagagt aaatgcgtta tttaatgaag aaagtataaa gaaagagata gaaaatgcaa
    10561 tacttttgaa aaatagtata aatcttaagt ctataaaaaa gattgaaaaa aatatccctt
    10621 ttataggtaa attaattgaa gaggataagt tctttatatt gaataagagt acgtttatgg
    10681 aaaatttaga agatatgtta gaaaaattag ttcataaagg aattattgat atagagttca
    10741 aaaaaaaggt attaaaaaga gaaaagaaat cttcaacagc attagataat tatatagcat
    10801 tgcctcactc agttaatact aatggggaaa atctttatct gtcatttgga atattagaaa
    10861 aaccagtggt ttgggataca aaggaaatta gaataataat attgatgata attccagata
    10921 agaatgtaga tagtacagac ctgataataa aaagttatga agaagtactt gaagtaggga
    10981 gagataaaaa aatgatagaa gaacttgcta aagtaaaatc atttgatgaa ttttataaaa
    11041 taattaccaa gaggaggtaa taatatggac ccagtaattt ttattatagc atcacttatt
    11101 acagtgtatt tattaaatat ttttcttgga tacttacagc ttaaagattt taataaaaat
    11161 tatattgaac taaaaagaaa aggaagagtg gcaataggca gaaaaaaagg aagaatttca
    11221 tcaggtacaa ttgtgttgat acttataaat gatgatggtg tgattgtcga aactagaaaa
    11281 atgcaaggtg ttacagtatt ggcaagagta aagtcatttg aaggtttggt aggaaagagc
    11341 ttagagtaca tagaaaaatc agatttaact gtttacaata aactacttaa aaaagcaata
    11401 ctagatgcag tcaaacagta cataacattt gagaaaaata aatgtgaaga tacaaataat
    11461 ctgagtactg atgaagagtg taggatggaa gtagtttaaa aaaatatatt tataaggagg
    11521 agttaatatg acgcaatttt ttcaagtatt agcaagtggt gcagatagtt ttatgaattt
    11581 atttagggca ggtgggcaac aatttgtagg ttttgtaaca gatatagtac cacttttagt
    11641 agcattatta gttacaatga atgcaattat caactttatt ggtacagata gagtcgagag
    11701 acttgcaaaa aaatgttctg caaatatatt tactagatat ttgatattac cagtccttgg
    11761 tacatttgta tttgcaaacc caatgacact atcactagga agattcttgc cagaaaagtt
    11821 taaacctagt tactttgcag cagcaagctt ttcatgccat acaatgaatg gattattccc
    11881 acatatcaat ccaggtgaac tatttatata tctaggaatt gcaaatggta taacaacttt
    11941 gggattctca acagcagatt tagcagttag atatttgtta gtgggtatag ttgcaaactt
    12001 tattaaaggt gtagttactg actatacaac aaaatttgta gagaaacaac aaggaatagc
    12061 attaaattca gatataaaga ttggataatt actttaaggt ataaataaat ttttcaaata
    12121 aaaagatagt gtatagagga ggataaatta tatggcattt aacaaagtta aaatagtaaa
    12181 aggttctgga ggatggggtg gaccattgat aatagaacca acagaaaaga agaataaggt
    12241 agtatatgtg actgggggag caaagccaga aactgcagta aaaatagctg aacttacagg
    12301 atgtgagtta atagatggat tttcacaggg tgttaaagat gatgaaatcg catgtgtaat
    12361 aataaattgt ggtggaacat tgagatgtgg tatatatcct caaaagaaaa taccgactat
    12421 aaatataatg aaaacaggaa aaagtggacc attagcaatg tttataaaag aagatatata
    12481 tgtttcaggg gtaaaaccaa caaatgtaga gcagttataa ttgaggtagt aggagggaag
    12541 aaatatggct tatgatacta aaaagaagat aagtgagcag agtcaaggaa ttgttgcaaa
    12601 aataggtata gcactaggaa atgtgacaag tactcttttt caagctggta gggatactat
    12661 agatacatta atacatacta tactgccttt tatggctttc gttgcagtcc taataggtat
    12721 aataaatcaa tcaggtatag gaaattgggt agccaattta cttactccat taatcggaaa
    12781 tgttggaggt ttagttgtct tatcaataat atgttcattt ccgttgttgt ctccgtttct
    12841 tggaccagga gctgttatag ctcagatagt gggggtattg gttggtacag aaataggaaa
    12901 aggaaatatt ccaccaagtt tagcattacc agcattgttt gcaataaact cacaagcagc
    12961 ttgtgacttt ataccagtag gtcttggtct tgcagaagct gaacctgata cagttcaagt
    13021 aggagttccg tcagttttat attctagatt tttaacaggt gcaccaactg ttctattagc
    13081 atggttagca agctttgggt tatataaata gaagaatact ttataaataa ttagagagag
    13141 gttcagttga tatggaatta atatacagta ctcaaataaa taaaatagga gataatgcaa
    13201 atgaattttt acaacataat atgtttgtaa ctttcaaaga taatgctcct caagagttag
    13261 aaaattactg ttatatacat tctgaaaata atttagtaaa agaaatactt acgaatgatg
    13321 tgttatcaat aaataatgtt gattacaaaa ttacttctgt tggtgagtta gtaaaccaaa
    13381 atctttcaga attaggtcat ataacattta agtttacagg tgaaaaagat ggagcaattg
    13441 gagggacctt atatcttgaa gaaaaagaaa tagcacctat tggcgtaggt actatactaa
    13501 aaataattag aaaataaaat ttaaaacgaa tctaatcata ttataagtaa attatagata
    13561 aaagtcaatt taactaatca agttaacttt taatgtgata aaaaagggga aatgaaaatg
    13621 agaaaagtgg ctttagttgt tggaggagga agaagtttag gtgaatattt atctaaacat
    13681 ttagctaaag taggttatga tgttgctatt gcagatttaa atgaagacaa cgcaaaaaaa
    13741 gtagctgaag aaatagaaac tgaatttggt tgtaaatctg taggatatgg ttgtaatgcc
    13801 atagatgaaa gacaggttat aagcactgtt aaagctattg aaaatgattt tgatagaata
    13861 gatttattag tgtacaatgc aggagtggct gtaagtaaaa aaataactga ttttggatac
    13921 aaagatttta aatttattgt agacgtaaat ttaaatgggt actttctatt tgcaagagaa
    13981 gtatctaaag tcatgatagc aaaaggtatt gagggtagaa tcatacagat aaattcaaaa
    14041 tcaggtagag tgggaagcaa gcataattca ggatattcag caggtaaatt tgctggagta
    14101 ggacttactc aaagtttagc gctagatttg gcagaacata agataactgt aaatgcactg
    14161 atgctcggta atttacttga ttctgatatg tttgaaagtt taattcctca atatgcagta
    14221 aaattgggaa tacctgaatc agaagtcaag caagtttata tagataaagt acctttaaaa
    14281 agagggtgta gatttataga tgttgcaaat atgcttacat tttatgcttc aaaggaagct
    14341 gaatactgta ctggtcaatc tataaatatt actggtggac aagttatgta aggtttttat
    14401 ggagtgtctc aagatgaact ctttagttca tgaggcactt tttttgtata aaattaaata
    14461 tattttcatc atttaaacaa tgaaaaagag gtttatcttt attttgagat agcctcattt
    14521 ttgtaattaa gaaacatagt gtttaagtaa acatataaga ttgttagttt tttaaaagag
    14581 aattttttaa taatattata tttatgaagt atttttaaac ttaatttgat taaaaaatag
    14641 ctacgcacac ttgtgacttt agtcatgagt tagtagctaa attagtcagc atatagggaa
    14701 acttatatgt agagatagga tagaacctat ccaatactac ttgaattgct aaaaacccct
    14761 aaagctaacc aaactaaaac ataagg
//
LOCUS       DAMJYN010000089        14526 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.093, whole genome shotgun sequence.
ACCESSION   DAMJYN010000089 DAMJYN010000000
VERSION     DAMJYN010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14526)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14526)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14526
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.093"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(<1..1018)
                     /locus_tag="PC466_003018"
     CDS             complement(<1..1018)
                     /locus_tag="PC466_003018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HDF2770380.1"
                     /translation="MKRVYIDFEMNMPNSKSKRAVFNSDIIAIGAVMYDEKTKNIDKF
                     KSLIRPVSNEELYPHIQELTHISSEELKSAPSYEEVMRKFKKWLGIFSDIKGIYTFGN
                     LDLTCFNNTDMRSAKKNNHPRFVNNIRDLFVDIKEKYINCGMRCMNYISLKNLLEFVN
                     LEFSGDAHDPLNDAYNLFILDEAITNNVDIQNLLIIRDIIRPPFNDINSNLDNCFNKF
                     KESLYKKEGNYNIVDFSVEIIKTVRMYLLTIIDVNIQNLEIMKDINKKMDTIDKLKDI
                     EEGYFYLLEDVYLDMKDVLEDLMLYRMNEDEYKYEIKNIIKMFDEDLDNEKIYINKCN
                     NLNVV"
     gene            complement(1066..1926)
                     /locus_tag="PC466_003019"
     CDS             complement(1066..1926)
                     /locus_tag="PC466_003019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiocytidine(32) synthetase TtcA"
                     /protein_id="HDF2770381.1"
                     /translation="MSELSGKGCEIIVPFEERLPVRDIEKSIIKKYRKNLWSKFMKSI
                     RDYKLVEEGDKIAVAISGGKDSILMAKMFQELKKHGQVNFDVEFIAMDPGYHANIRQL
                     LIDNCEYLNIPIHLFDSRIFEIADEIAKDYPCYMCARMRRGALYSKAEELGCNKLALG
                     HHYDDVIETTMLNLLCAGNFKTMLPKLNSTNFEGIKIIRPLYYIREEHIIRFIQNSGI
                     WPLNCACMVAAKKTGNKRYEIKDLIKSLESNFKNVEKSIFKAAENVNLDSVLGWQKDG
                     EKHSFLENFE"
     gene            2205..2414
                     /locus_tag="PC466_003020"
     CDS             2205..2414
                     /locus_tag="PC466_003020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat associated protein CotJA"
                     /protein_id="HDF2770382.1"
                     /translation="MENKTRDIKKNCGPSLARPYINNQIFTEMYCLSDALKFGTIFPE
                     LNLLESEMYNKELYAKPKKYRGGRR"
     gene            2414..2680
                     /locus_tag="PC466_003021"
     CDS             2414..2680
                     /locus_tag="PC466_003021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat protein CotJB"
                     /protein_id="HDF2770383.1"
                     /translation="MKDSSRAELMRKVQETSFACVDMNLYLDNHPDDKNAINTYNSLC
                     NQFAQARYAYENKYGPLTNFGYAPSRCPWQWADQPWPWDREFNY"
     gene            2709..3281
                     /locus_tag="PC466_003022"
     CDS             2709..3281
                     /locus_tag="PC466_003022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000265278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HDF2770384.1"
                     /translation="MWIYQKTIQHPVNIKTCDPRMAKFLITQFGGPNGELAASLRYLS
                     QRYTMPTGNMRALLTDIGTEELAHVELICTMVYQLTSDASPEELKAAGLGSNYAQNGY
                     GIYPTDSNGVPFDVRPIAVMSNPVTDLHEDMAAEQKALATYYQLINLTDDVDVIDVLK
                     FLGQREIIHYQRFGEALMDAYELEESQKMF"
     gene            complement(3515..4705)
                     /locus_tag="PC466_003023"
     CDS             complement(3515..4705)
                     /locus_tag="PC466_003023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HDF2770385.1"
                     /translation="MNFNQKRIAASIMATAIIMPTMGNLAYANESEVESVSIESRTIT
                     GNAVNFRKGPGTNHESMGKLYKGDKVEYVGKEGSWVKVKYNGNTGYVHGNYVAINSLG
                     SSNESSDTSVKSTKVVTAKGLNFRTGPSTSSSKISTLGYGTEVGYISESNGWSKISSN
                     GRVGYVSSKYLGTSVNDSTNENVENSSNDLVKGTKVVTAKSLNVRTGPGTSHSKIATL
                     SYGTEVGSISESGGWTKVSYGNQTGYVSSQYLAEKGSVDTSIPSYSTNSPSQGADSVI
                     SFAKTLLGKPYVWGAEGPNSFDCSGFTQYVMKKSAGVSIPRVSRDQSKYGTYVNRGDL
                     RSGDLVFFDTQGSNNGSVSHVGIYIGNGDMIHASSGSSKKVTISNINSSYYSSRYVNA
                     RRVL"
     gene            complement(4965..5396)
                     /gene="dut"
                     /locus_tag="PC466_003024"
     CDS             complement(4965..5396)
                     /gene="dut"
                     /locus_tag="PC466_003024"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HDF2770386.1"
                     /translation="MYNLKVKKLNDDAIIPNFAHKGDAGMDLYSIEEVVIPPGETKLI
                     KTGICIELPTMTEAQVRPRSGLALKHSVTVLNTPGTIDEGYRGELKIILINHGKNDFK
                     VEKHMKIAQMIVKPIYDINIEEVKELSDSERGKGGFGSTGF"
     gene            5509..7737
                     /locus_tag="PC466_003025"
     CDS             5509..7737
                     /locus_tag="PC466_003025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IA DNA topoisomerase"
                     /protein_id="HDF2770387.1"
                     /translation="MKLVLAEKPSVAKTIASFLGAKTRQDGYFEGNDYIITYAVGHLV
                     SLYDMKDYDKDKYSGSWKMNNFPFVPEDKFKFKIDSSKTKQFNTVKKLLNRKDVEYVI
                     NATDNDREGELIAFLIFLLAKNKKPVKRILVNEWTPEDITRGIKNLKDEYEMRNLQAA
                     GYTRLITDWLIGINFTSVATLKYGNGKLLNIGRVILPTVKLVYDRDMEILNFVPKTYY
                     EIEGHFKAEAGEYKGKYVKGKESKFDTLEDANKIIASITSETGKILDKKVTMSKEYAP
                     KLFSLTSLQGYITSKYSNFTSDKVLNVCQSLYEGNGKGGYITYPRTDSIFLEESLASK
                     ASQTLDKLKVGLEYENKIKFSKTKRVFDSSKVDSHSAIIPTYIIPKSLSKDEQLVYDA
                     IKDRFVANFMPPAEYENTEIKTEVDNCTFLTKGKVLKSKGYLEVYNKEEKNDLLPLVN
                     KDDVVDVLEIKPLTKQTTPPKPYTEDTLLKAMKNCGKNVPEEDTTVLSGYSIGTSATR
                     ADVLKKISQVGYVKKKGKSYSITDLGKNLVEIFPVKDLFDVDYTGKLEKSLSDIQKGK
                     YTRKEYLTNIISFIYQNVNIIKQDASKNINTEAYTFDSKTKKFTKTKEKKQKKDVTNT
                     EKEVAISKDSNNKKEVKNGDENQSLGKCPICQGDVLEFDKGFACKNHKECKFVIWKND
                     KYLSLYKKKVNKTMVKNILKKGETKVKSLTAKNGNKFDATLKYDKNPDTGYFNWKIEF
                     DN"
     gene            complement(7848..8333)
                     /locus_tag="PC466_003026"
     CDS             complement(7848..8333)
                     /locus_tag="PC466_003026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF2770388.1"
                     /translation="MDNNNILKIADSFLDFLFVLENNIFKESDLLKKFQNNSDIMKAY
                     FEECPMAPSHAKVILYLMTSNSSSISQIASNLGILKSNMTPIIDRLVEHGLVNKFPDP
                     KDRRILRVELTDKAFKLFDAVKAILKESLVKKLSNLSEEELTLLDEHTLKLSEIVKKL
                     G"
     gene            8585..9808
                     /locus_tag="PC466_003027"
     CDS             8585..9808
                     /locus_tag="PC466_003027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HDF2770389.1"
                     /translation="MKRYLIVFLMCSSLFLVGCGKTKESEPEKPIAVSVQKAVGGEIE
                     NTNSFSGTTKVKDETAVTAQTVGTVQEVYVKLGQNVRKGDELLSISSPELENSVKQSK
                     ASLDLAKASYSSATGGSLEAQVNQAKTALDNAKIQYEESQRNYDNNKILYEQEVISLD
                     QFKKIEFSLEQTKQQLDSAQRAYDTATSKSIPQAKALAKKQLDQAQVSYNLAMSNLDK
                     LTLTSPVDGTITAKNFDSKEMITQSQPAFIISNPNILEVDLNVAESDIGKFKKDGNVD
                     VIIEDQRILGKIDYVPSVVDPQTSLYPVKVLVNNANNKFKAGMSAQVNLSIEKENGAV
                     TVPKKAIFEENGKKYVYIATKDNIAKKHLVQTGIVTEDKIEIKSGVSDKDTVIIGGIS
                     LISDGTKIFPVEKEK"
     gene            9812..12946
                     /locus_tag="PC466_003028"
     CDS             9812..12946
                     /locus_tag="PC466_003028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter permease subunit"
                     /protein_id="HDF2770390.1"
                     /translation="MNLTQTSVKRPLTIIMVFLVLIVFGGIGYKKMSINLMPDIEIPV
                     VMVMTTWTGAGPQDVDEQVSQKVDESLSAVSNVKSTISSSQESVSMVVAQFEFGTNLD
                     EIMNDVRSKVDALQTSLPDDAAKPTVLKLDMNAQAIGQLVISGGNENSSQALRKYAED
                     VIQPKIESIDGVTSADLKGGEKAQVNVIADPAVLSNYGVSLSTIKGVLSSSNKTFPYG
                     SITQGEDKIVLRAIDKLESLDDIKQIQIPVKGGNTVRLDNLCSVDYGYADKDSIYRYN
                     GKDSLVIDISKQQDANTVKVMQSAYKYVDELNKENPQFKIKIANDTSSYISESINSVM
                     SNLLISAVIAFIVIFAFLKSVRASLVVAVAIPISIIGAIAILYFTGESLNLITASSLV
                     ISVGMVVDNATVVIENIFKYRKSGRLSLDDCAIEGTRTVTNAILASTLTTIAIFLPIM
                     FTEGIAKITFGALGKTLIASLAFSFIGAITLVPSVFAKLSRGKNSQKMQEKDSPIFDK
                     VSEAYKKLLSVCLRHQRLVVISSLLIFVASLFGMGFIGMDFMPAADKGELSISIELPK
                     GLSLESNDYYVSMTEKKVSDIPEIKTLITTLTSDSNNSKASIAIELESQKNRKRTTDE
                     IEKEIIDRVATVPDCKINVSQNSSVMGGAGGADFTLEMKGPDLDVLKILGKEAEKEFS
                     SIKGFRNVETSLTDTTQEAQFTIDKHKAQEYGVNTAEIAGMLRTAINGDSVTTATIDD
                     YKVDVNLKFKADTIDSLEDIKQLKVNSATGKEVPLGAFSDIKMADGLQSISRTDGDFS
                     VNITATLDNLDAGTATKLALEKTNKMVIPKDYSIGVGGETEMMNESMASLGFSMVIAI
                     ALVYMVMVAQFESFSKPFIIMFCVPFAFVGVVLSLLVSGQSLSTVGMLGIILLIGIVV
                     NNGIVLIDYIEQLRKTNRNNDLIGLVSIGCAARLRPVLMTTATTILGMLPTALSLGEG
                     GETMQPLAIVIMGGLTVSTLITLVLIPTIYLIFDKWENKFSDKMPKIFGKITDKIGSI
                     KRKIIKKPKLKAKV"
     gene            12980..14278
                     /locus_tag="PC466_003029"
     CDS             12980..14278
                     /locus_tag="PC466_003029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TolC family protein"
                     /protein_id="HDF2770391.1"
                     /translation="MSKIVAIGCGVGIITANLIPVYADNNTSSINNVDNSILSDSNKR
                     TSEKEILTAREAVSAALKNSEKLKMKSEEIKMLKEKLEVQDEFDSFTGSDNSFPYDQI
                     GLLKNQSEQAKGFMEDQIANDITNKFNDLVSRENELDKIKNNLEIKTKEIKDMKLKKD
                     LGLVTSLETESAELELQTLQNTQKAKLQELKNNQDYFKLLTNIDLNNYQLDKEYRFES
                     FRVGGSVDSYMEGKVNEYLKYDQLILERTEESFNDKDENKADLPDRPNLTRPVAPTKP
                     EQGNLTDDEYKVLMDKYEKDYKRYEKEVEAYNLERQTYAAGLTTYANYLQQKFNTENG
                     LVTLEDSKKALKKGLIDSYAQLLALEDTIQITKKQLDLSEKQLKNTKLRYDLGLITLT
                     DYKKQVVSNQDAKNSYDTLIVNYNSLKNGIEKPWILNTGK"
BASE COUNT         5362 a         2123 c         2133 g         4908 t
ORIGIN      
        1 taacaacatt taagttatta catttattta tatatatttt ttcattatct aagtcttcat
       61 caaacatttt tattatattt tttatctcat acttgtactc atcttcattc attctataaa
      121 gcattaaatc ttctaataca tctttcatgt cgaggtacac atcttctaat aaataaaaat
      181 agccttcctc tatatctttc aatttatcta tagtatccat ttttttattt atatctttca
      241 taatttctaa attttgtata tttacatcta tgattgttaa taagtacatt ctcacagttt
      301 ttattatttc aacagaaaaa tctacaatat tataatttcc ttctttttta tataatgact
      361 ccttaaattt gttaaaacaa ttatctaaat tagaatttat atcgttaaat ggtggtctta
      421 ttatgtcacg tattattaaa agattttgta tatctacatt atttgtgatt gcctcatcca
      481 aaataaataa attatatgca tcatttaatg ggtcatgggc atctccacta aactctaagt
      541 taacaaattc aagtaaattt ttcaatgata tatagttcat acatctcata ccacaattta
      601 tatatttttc ttttatatct acaaataaat ctctaatatt atttacaaac cttggatggt
      661 tatttttttt agcacttctc atatctgtgt tattgaaaca tgtcaaatcc aaattaccaa
      721 aagtatatat tcctttaata tcagaaaata tgccaagcca ttttttaaat tttctcatga
      781 cctcttcata acttggtgca ctcttcaatt cttcagaaga tatatgtgtt aattcttgta
      841 tatgaggata taactcctca ttacttactg gtcttattaa agatttaaat ttatcaatat
      901 tttttgtttt ttcatcatac ataactgctc cgattgcaat tatatcagaa ttaaatactg
      961 ctctttttga tttagaattt ggcatattca tttcaaaatc tatatatact cttttcaata
     1021 taaacaccct ttccaattgt ttatagtgat tctttttaac tatttttatt caaaattttc
     1081 taagaaagaa tgtttctccc catctttttg ccaaccaagt actgaatcaa gatttacatt
     1141 ttctgctgcc ttaaatatag atttttctac atttttaaaa tttgattcta agctctttat
     1201 taagtctttt atctcatatc ttttattacc tgttttttta gcagcaacca tacatgcaca
     1261 atttaatggc catataccac tattttgaat aaatcttata atatgttctt ctcttatata
     1321 ataaagtggt cttataattt ttataccttc aaaattagta gaattaagtt taggaagcat
     1381 tgttttaaaa tttccagcac acaataagtt aagcattgtt gtctctatta catcatcata
     1441 atgatgacct aatgcaagtt tgttacaccc taattcttct gcctttgaat ataatgctcc
     1501 tctcctcatt cttgcacaca tatagcatgg ataatctttt gctatttcat ctgctatctc
     1561 aaatattctt gaatcaaata aatgtattgg tatatttaga tactcacaat tatctataag
     1621 taattgtctt atatttgcat ggtatccagg gtccatagca ataaattcaa catcaaaatt
     1681 aacttgtcca tgttttttta actcttgaaa cattttagcc ataagaatac tgtcttttcc
     1741 accagaaatc gctacagcta tcttatcccc ttcttcaacc aatttataat ctcttattga
     1801 cttcataaac ttagaccata aattttttct atatttcttt attatacttt tttctatatc
     1861 tcttactgga agtctttcct caaaaggaac tataatttca cagccttttc ctgatagttc
     1921 actcatctaa tcacctcgta tatttatgta tatttatgtt aataatattt tacaaaaaag
     1981 tctaccttca tccacaaaat actataattt ttactttaat tttactaaat aatttatagt
     2041 ttacaataac acataaactt ataataacat aaataacctc tttcttttat tatctttttt
     2101 atttttctca tttaatattt tattattagt aacgattttt aaatgattga atattataca
     2161 ctagatagag ttacctatct atttacaaca aggaggtttt catcttggaa aataagacta
     2221 gagatatcaa aaaaaattgt ggtccatctt tggctagacc atacattaat aatcaaattt
     2281 tcacagaaat gtactgcctt tctgatgcat taaaatttgg aactatattt ccagaactaa
     2341 acttactaga gtctgaaatg tacaacaaag aattatatgc taagccaaaa aaatatagag
     2401 gaggtagaag ataatgaaag actcatctag agctgaactt atgagaaaag ttcaggaaac
     2461 atcttttgca tgtgttgata tgaacttata tttagacaat caccctgatg ataaaaatgc
     2521 tatcaacact tataattcat tatgtaatca atttgcgcaa gctagatatg cttacgaaaa
     2581 taaatacggt cctttaacta actttgggta tgctccaagt agatgccctt ggcaatgggc
     2641 tgaccaacct tggccttggg acagagaatt taattattag acatcaagta ttggaggatt
     2701 gaaaattcat gtggatatat cagaaaacta tacaacaccc agttaatata aaaacttgtg
     2761 accctagaat ggctaaattt cttataactc aatttggtgg gccaaatgga gaacttgctg
     2821 catctttaag atatttaagc caaagatata caatgcctac tggtaatatg cgtgcacttt
     2881 taacagatat tggtacagaa gagctagctc acgttgagct tatatgtact atggtttatc
     2941 aattaacttc tgatgcaagc ccagaagagt taaaagctgc aggtcttggt tcaaactatg
     3001 ctcaaaatgg atatggaatt tatccaacag attcaaatgg tgttccattt gatgtaagac
     3061 ctatagcagt tatgtcaaat cccgtaaccg acttacatga ggatatggca gctgaacaaa
     3121 aagcacttgc aacttattat caacttataa acctaacaga tgacgttgat gttatagatg
     3181 tattaaaatt cttaggtcaa agagaaataa ttcactatca aagatttggt gaagctttaa
     3241 tggatgctta cgagttagaa gaatctcaaa aaatgttcta aaatttttat ttgtataact
     3301 attattattt gataatttat aatttactgt tgtgttaaaa tttataaaaa atataaatat
     3361 aatttatttt ctataaacag agaaaataaa taaaaagcag gtatcaatca aatagtaaca
     3421 tgtattatac tatacattac tatcaatatt gtacctgctt tcatattata agcaataaag
     3481 aaaaatctat ttattaggtt ttataataaa acaattataa aactcttctt gcatttacat
     3541 atctacttga atagtagcta ctatttatat tagatattgt tacttttttt gatgaacctg
     3601 aagatgcatg tatcatatct ccatttccta tgtatattcc aacatgactt acagaaccat
     3661 tatttgaacc ttgtgtatca aagaatacta aatctccact tctaaggtct cctctattta
     3721 catatgttcc atacttactt tggtctctag atactcttgg tatactaact cctgcagatt
     3781 ttttcataac gtactgtgtg aatccagaac agtcaaaact atttggacct tctgctcccc
     3841 atacatatgg ttttccaagt agtgtctttg caaaacttat tacactatca gctccttgac
     3901 ttggagaatt agtcgaataa gatggaattg aagtatcaac agaacctttt tcagcaaggt
     3961 attgacttga cacatatcca gtttgattgc cataacttac ttttgtccat cctccacttt
     4021 cagaaatact tccaacctca gtaccataac ttaatgtagc tattttagaa tgacttgtac
     4081 ctggtcctgt tctaacgttc aatgactttg ctgttacaac ctttgtaccc tttacaaggt
     4141 catttgaact gttttcaaca ttttcatttg tagagtcatt tacactagtt cctaaatatt
     4201 tacttgaaac ataacctact ctaccattag aacttatttt tgaccatcca tttgactcag
     4261 atatgtatcc gacttcagtc ccatatccta gtgttgatat tttagaacta cttgtacttg
     4321 gtcctgttct aaaatttaat ccttttgctg ttacaacttt tgtcgactta actgaagtat
     4381 cactactttc attgctactt ccaaggctat ttattgctac ataatttcca tgcacataac
     4441 ctgtgtttcc attatattta acttttaccc aagaaccttc ttttcctacg tactcaactt
     4501 tatcaccttt gtaaagtttc cccattgatt catggtttgt acctggtcct tttctaaaat
     4561 ttaccgcatt ccctgttatt gttctgcttt ctatactcac actctctact tcagactcat
     4621 tagcatatgc taaattcccc atagtaggca ttattatcgc agttgccatt atactggctg
     4681 ctattctctt ttgattaaaa ttcataactt tccactcatc tcctcttttc tactatcttt
     4741 atttcacttc aaaatataaa agaaataatt gacactatta aaatatcaat tatttctttt
     4801 atattaatat tattacaaat ttgtaactat ttgtctatag taatatttgc ttaccataaa
     4861 ttaccatgta taaattttaa tcttcaatag cctgtaattt agtaatatag ccatctttta
     4921 ccttttttaa aaatggctat attttttaac ttttttgtaa ctttttaaaa tccagttgag
     4981 ccaaacccac cttttcctct ttcggagtca cttaattctt ttacttcttc tatgttaata
     5041 tcatagatag gttttactat catttgagca attttcatat gcttttcaac cttaaaatca
     5101 tttttcccat gatttattaa tataatttta agctctcctc tgtatccttc gtcaatagtt
     5161 cctggtgtat ttaatacagt aacagaatgc tttaaggcaa gcccacttct aggtcttacc
     5221 tgcgcttctg tcatagtagg aagctctata catatcccag ttttgataag tttagtctct
     5281 ccaggaggta ttacaacctc ttctatagaa tacaaatcca taccagcatc acctttgtga
     5341 gcaaaattag gtattatagc atcatcattt aattttttta cttttaaatt gtacatctta
     5401 tatctccttt caactttcta taaatattat aacttaaatt tcgacctctt gaagtttttt
     5461 atttttttgt ggtaatataa ttattagtgt tttaaaggag gattttttat gaaacttgta
     5521 cttgctgaga aaccatctgt ggcaaaaact atagcatcat ttttaggtgc aaagaccaga
     5581 caagatggtt actttgaagg aaatgattat ataattactt atgcagttgg acacttagta
     5641 tcattatatg atatgaagga ttatgataaa gataaatact ctggctcttg gaaaatgaac
     5701 aatttcccat ttgttcctga ggataagttt aaatttaaga ttgatagttc taaaactaaa
     5761 caattcaaca ctgtaaaaaa gcttttgaat agaaaagatg tagaatatgt aataaatgcc
     5821 actgacaatg accgagaagg agaacttata gcatttttaa tatttttact ggcaaaaaat
     5881 aaaaaaccag taaaaagaat cttggtaaat gaatggacac cagaagatat tacaagaggt
     5941 ataaaaaacc taaaagatga atatgaaatg agaaatcttc aagctgctgg atatactagg
     6001 cttattactg actggttgat tggaataaat ttcacttctg ttgctacatt gaaatatgga
     6061 aatgggaaac tattaaacat aggtagggta attcttccaa cagttaaatt agtctatgat
     6121 agagatatgg aaatactaaa ctttgttcct aaaacttatt atgaaataga aggacatttt
     6181 aaagctgaag ctggtgaata taaaggtaaa tatgttaagg gtaaagaaag taaatttgat
     6241 acacttgaag atgcaaataa aattatagct tcaattacat ctgaaactgg taaaatacta
     6301 gataaaaaag ttactatgtc aaaggaatat gcaccaaaac tttttagttt gacatcactt
     6361 caaggatata taacttctaa gtattccaat tttacatctg ataaggtttt aaatgtctgt
     6421 caatctctct atgagggtaa tggtaagggt ggatacataa cttaccctag aactgattcc
     6481 attttcttag aagaaagttt ggcttcaaaa gcttctcaaa ctttagataa attaaaggtt
     6541 ggtcttgaat atgaaaataa aattaaattt tctaaaacta aaagagtttt tgattcttct
     6601 aaagtagact cccatagtgc tataattcca acttatataa ttccaaaaag tttatctaag
     6661 gatgaacaat tagtttatga tgccataaaa gatagatttg tagcaaactt tatgcctcct
     6721 gctgaatatg agaatacaga aattaagact gaagtagata attgtacttt cttaacaaaa
     6781 ggtaaagtgc ttaaatcaaa aggatacctt gaggtatata ataaggaaga aaaaaacgat
     6841 ttacttccac ttgtaaataa agatgatgtt gtagatgtgt tagaaataaa accattaact
     6901 aagcaaacta ctccacctaa accatatact gaggacaccc ttttaaaggc tatgaaaaat
     6961 tgtggtaaaa atgtgcctga agaagataca acagtgctat ctggatattc gattggaaca
     7021 tcagccacac gtgctgatgt gttaaagaag ataagtcaag tgggctatgt aaagaaaaaa
     7081 gggaaatctt attctataac agaccttggg aaaaatttag ttgaaatttt tcctgttaaa
     7141 gacttatttg atgtagatta tactggaaaa cttgaaaaaa gtttaagcga tattcaaaaa
     7201 ggaaagtata caagaaaaga atatcttact aatatcatta gttttatata tcaaaatgtc
     7261 aatattataa aacaagatgc ttcaaaaaat ataaacacag aagcatatac tttcgattca
     7321 aaaactaaaa aatttactaa aacaaaagaa aaaaaacaga aaaaagatgt aactaatact
     7381 gaaaaagaag ttgctatatc aaaagattct aataacaaaa aagaagttaa aaatggtgat
     7441 gaaaatcaat ctcttggcaa atgccccatt tgtcaaggtg atgtactaga atttgacaaa
     7501 ggctttgctt gtaaaaatca taaagaatgt aaatttgtta tttggaaaaa tgataagtat
     7561 ttaagtcttt ataaaaagaa agttaacaaa acaatggtca aaaatatttt aaaaaaaggt
     7621 gaaactaaag taaaatcttt aactgctaaa aacggtaata aatttgatgc tacattaaaa
     7681 tatgataaaa atccagatac cggctatttc aattggaaaa tagagtttga caactaaata
     7741 ttcataagaa aagaaatagc agtagtataa taatctatat tatattactg ctatttcttt
     7801 tcttatgaag ttttaacttt tttaatagtg acttttacaa tcacactcta acctaatttc
     7861 tttactattt ctgataactt taatgtatgt tcatctaata aagttagttc ctcttcagaa
     7921 agattagata atttttttac tagagattct ttgagaatag cttttactgc atcaaataat
     7981 ttaaatgctt tatctgttaa ttcaacccta agaatccttc tatcttttgg gtcaggaaat
     8041 ttattgacta aaccatgttc cactaatctg tcaataatcg gagtcatatt tgattttaaa
     8101 attcctaaat tagaagctat ttgagaaatt gatgatgaat ttgatgtcat aagataaaga
     8161 attaccttag catgtgatgg agccattgga cattcttcaa aataagcttt cattatatca
     8221 gagttatttt gaaacttttt taacaaatcg ctttctttaa atatattatt ttcaagcaca
     8281 aataaaaaat ctaaaaaaga gtccgctatt ttaagtatat tgttgttatc catatttgta
     8341 acatcccttc aatagataat ataataaaac attgttgttt aatatagtat aaattataaa
     8401 ctattaataa atttaaaaca agaaaaagtt attgactcat aataattata aatttataat
     8461 caaattagag aattataaat tgccaataaa gggaagtttt ttaattagtc taaaactaaa
     8521 cttaaattat aagacacttt aaattctaca acaagctagt gtgcaatata taataggagg
     8581 agatatgaaa agatatttaa tagttttctt aatgtgtagt tcactgtttt tagttggatg
     8641 tggaaaaaca aaagaatctg aacctgagaa accaatagca gtttctgttc aaaaagcagt
     8701 aggtggagaa attgaaaaca caaattcttt ctcaggaact acaaaagtta aagatgaaac
     8761 agctgttact gcacagactg ttggcacagt tcaagaagtg tatgtaaaac ttgggcaaaa
     8821 tgtaagaaaa ggagatgaat tattgagtat aagcagtcca gagctagaaa atagtgtaaa
     8881 gcaaagtaaa gcctcactag atttagcaaa agcaagttat tcaagtgcca ctggtggttc
     8941 attagaggca caagtaaatc aggcaaaaac agctcttgac aatgcaaaga ttcaatatga
     9001 ggagtctcaa agaaattatg acaataataa gattctttat gaacaggaag tcattagttt
     9061 agaccaattt aaaaaaatag agttttcttt agagcaaaca aaacaacagt tagattctgc
     9121 tcaaagagca tacgatacag caacttcaaa aagtatacct caagctaaag cacttgctaa
     9181 aaaacagctt gaccaagctc aagtatcata taatttagca atgagtaatt tagacaaatt
     9241 aacattaaca tctccagtag atggtacaat aacagctaaa aactttgatt caaaggaaat
     9301 gataacacaa tcacaaccag cttttattat ttctaatcct aatatactag aagttgattt
     9361 aaatgtagca gaatcagata taggtaaatt taagaaagat ggaaatgtag atgttataat
     9421 tgaagaccaa aggattttag gaaaaataga ttatgtacct tcagtagttg accctcagac
     9481 atctttatat cctgttaaag tacttgtaaa taatgcaaac aacaaattta aggcaggtat
     9541 gtctgcacaa gtaaacttaa gtattgaaaa agaaaatggt gctgttacag tgcctaaaaa
     9601 agcaatattt gaagaaaatg gtaaaaaata tgtatacata gcaacaaaag acaatatagc
     9661 aaagaaacac ttggttcaaa ctggaattgt aacagaggat aaaatagaaa ttaaaagtgg
     9721 tgtaagtgat aaagatacag tgattattgg aggaataagt cttatttctg acggaactaa
     9781 gatatttcct gtagaaaagg agaagtagac tatgaattta acacagactt ccgttaaacg
     9841 tcctctcaca atcataatgg tctttttagt attaatagtt tttggtggta ttggatataa
     9901 aaaaatgtca ataaatctaa tgcctgatat agaaatacca gttgtaatgg tcatgactac
     9961 ttggacaggt gctggtcctc aagacgttga tgaacaagtt agtcaaaaag ttgatgaaag
    10021 tttatctgcc gtttcaaatg taaaatctac tatatcaagt tcacaagaaa gtgtttctat
    10081 ggtagttgct cagtttgaat ttggaactaa tttggatgaa ataatgaatg atgttaggtc
    10141 taaagttgat gcattacaga ccagcctccc agatgatgca gcaaaaccaa cagttttaaa
    10201 gctggatatg aatgcacagg ctataggtca acttgtcata tctggaggaa atgaaaatag
    10261 ttcacaagcc ttaagaaaat acgctgaaga tgtaattcag cctaaaatag aatccataga
    10321 tggtgttact tcagcagacc ttaaaggtgg agaaaaagca caggttaatg taatagctga
    10381 cccagctgtt ctttcaaatt atggagttag tttatccact ataaaaggtg tcttatcctc
    10441 tagtaataaa acattccctt atggttcaat tactcaaggt gaggataaaa tagttttaag
    10501 agcaattgat aaattagaat ccctagatga tataaaacag attcaaattc ctgtaaaagg
    10561 aggaaataca gttagattag ataatctttg tagtgtagat tatggatatg cagacaaaga
    10621 tagtatttat agatacaatg gaaaagacag tttggtaata gatatttcta aacaacaaga
    10681 tgccaacact gtaaaagtta tgcagagtgc atacaaatac gtagatgaat tgaataagga
    10741 aaatcctcaa tttaaaatta aaattgctaa tgatacaagt tcatacataa gtgaatcaat
    10801 aaacagtgta atgagcaact tgcttataag tgctgttatc gcatttattg taatatttgc
    10861 tttcctaaaa agtgtaagag cttcactagt tgttgcagtt gcaataccaa tttctataat
    10921 aggtgctata gcaattctct actttactgg tgaaagttta aatcttatta ctgcaagttc
    10981 attggtaatt tcagttggta tggttgttga taatgctaca gttgtaattg aaaatatatt
    11041 taaatatagg aaaagtggca gattgagtct tgatgattgt gctattgagg gaacaagaac
    11101 tgtaacaaat gcaatacttg catcaacatt gaccacgata gcaatattct tacctatcat
    11161 gtttacagaa ggtatagcta aaataacttt tggggcatta ggtaaaacac taatagcttc
    11221 actagcattc tcctttatag gtgcaattac actcgttcct agtgtatttg caaaattaag
    11281 cagaggaaaa aatagtcaaa agatgcaaga aaaagatagt cctatatttg ataaggtaag
    11341 tgaagcatat aaaaaattat taagtgtatg tttaagacat caacgcttag ttgtaatatc
    11401 aagtttactt atttttgtag cttccttatt tggaatggga tttataggta tggactttat
    11461 gcctgcagca gacaagggtg aattatctat ttctatagaa cttccaaaag gtcttagcct
    11521 agaatccaat gattactatg tatctatgac tgagaaaaaa gtctcagata ttccagaaat
    11581 taaaacttta ataacaactt tgacatcaga ttcaaataat agtaaagcaa gtatagcaat
    11641 tgaattagaa tctcaaaaaa atagaaaaag aactactgat gaaatagaaa aagagataat
    11701 tgatagagtg gctactgtac cagattgtaa aataaatgta agtcaaaaca gtagtgttat
    11761 gggtggagct ggaggagcag acttcacatt agaaatgaaa ggtcctgatt tagatgtatt
    11821 aaaaatactg ggaaaagaag ctgaaaaaga atttagctct ataaaaggat ttagaaatgt
    11881 tgaaacttct cttacagata caacacaaga agctcaattt actatagata aacataaggc
    11941 tcaagaatat ggtgtaaata ctgctgaaat tgcaggcatg ttacgtacag caataaatgg
    12001 tgactccgta accactgcta ctattgatga ttacaaagtg gatgtaaacc taaaatttaa
    12061 agcagatact attgatagct tagaagatat aaagcaacta aaagtaaact ctgcaactgg
    12121 aaaagaagtt cctcttggtg ctttttcaga tataaaaatg gcagatggtc tacaatctat
    12181 atctaggact gatggagatt tttctgtaaa tataactgct acacttgaca atttagatgc
    12241 tggtactgct acaaaactag cactagaaaa aacgaataaa atggtaattc ctaaagatta
    12301 ctctataggt gttggtggtg aaacagaaat gatgaatgaa tctatggcaa gtcttggatt
    12361 ttcaatggtc atagctatag cattagttta tatggtaatg gtagctcagt ttgaatcatt
    12421 tagtaaacca tttataatca tgttctgtgt tccatttgca ttcgttggag ttgtgctttc
    12481 gcttctagtt agtggtcaaa gtttaagtac tgtcggtatg ctaggtataa tcttacttat
    12541 cggtattgtt gttaataatg gtatagttct tattgactac atagagcaac ttagaaaaac
    12601 aaatcgtaac aatgatttaa ttggtttggt ttcaattggt tgtgcagcaa gattaagacc
    12661 agtcttaatg actacagcaa caacaatttt aggtatgttg ccaacagcac tatctcttgg
    12721 tgaaggtgga gaaactatgc aaccactagc catagttata atgggtggtc taactgtatc
    12781 tacacttata actttggtgc ttatacctac tatatactta atatttgata aatgggaaaa
    12841 taagttttca gacaaaatgc ctaaaatatt tggtaagata acagataaaa taggaagtat
    12901 aaaacgtaaa ataataaaga aaccaaaatt gaaagctaaa gtttaaatag aatggagggt
    12961 gattgtattg aataaaaaaa tgagcaaaat agttgcaatt ggctgtggtg ttggtataat
    13021 aactgccaat ttaatcccag tttacgcaga taataatact tcttctataa acaacgttga
    13081 taattctatt ttaagtgact caaataaaag aacatctgaa aaggaaattt tgactgctag
    13141 agaagctgtt agtgctgcac ttaaaaatag tgaaaaatta aaaatgaaat cagaagaaat
    13201 aaaaatgtta aaagaaaagt tagaagtaca agatgagttt gatagtttta ctggaagtga
    13261 caactcgttt ccatacgacc aaattggact tcttaaaaat caaagtgaac aggctaaagg
    13321 ctttatggag gaccaaatag caaatgatat tactaataaa tttaacgatt tagtttcaag
    13381 agaaaatgag ctagataaga taaaaaacaa tcttgaaata aaaactaaag aaattaaaga
    13441 tatgaaatta aaaaaagatt tagggttagt aacatcttta gaaactgaat cagctgaact
    13501 tgaacttcaa acactacaaa atactcaaaa agctaaactt caagaactaa aaaacaatca
    13561 agactatttt aagttattga ctaatataga tttaaataat tatcaattgg ataaagaata
    13621 tagatttgaa tcttttagag taggtggctc agttgattca tatatggaag gtaaggttaa
    13681 tgaatattta aaatacgacc aattgatttt agaacgtaca gaagaaagct ttaatgataa
    13741 agatgagaac aaagcagatt taccagatag acctaatctt acaagaccag ttgctcctac
    13801 aaaaccagag caaggtaacc taactgatga tgaatacaag gttcttatgg ataagtatga
    13861 aaaagactac aagagatatg aaaaagaagt tgaagcatac aatcttgaaa gacagactta
    13921 tgctgctggc cttactactt atgcaaatta tcttcaacaa aaatttaata ccgaaaatgg
    13981 tctagtaaca ttagaagaca gtaaaaaagc tcttaaaaaa gggttaattg atagctatgc
    14041 tcaattactt gctttagaag atacaattca gattactaaa aaacaacttg atttatcaga
    14101 aaaacaatta aaaaatacta aattaagata tgatttagga ttaattactc taactgatta
    14161 taaaaaacaa gtggtaagta atcaagatgc taaaaatagc tatgacactc ttattgtgaa
    14221 ttataactca ctaaaaaatg gtatagaaaa accttggata cttaatactg gaaaataatt
    14281 ctggtaaata gaaagattac tttaacatac gtttgattaa aaaatagtta tgcacactcg
    14341 tggctttagt catggaagat tcagaaggca aataatagaa atagattagt aaaaatatat
    14401 ttacttataa aactgtatac ttttatagag gctatctcaa aattggatat gtccctgtca
    14461 agtagacaga cttaaaaaag gctatcttta tgcggaatga gttcgatatt caatcgaact
    14521 cattcc
//
LOCUS       DAMJYN010000090        14224 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.094, whole genome shotgun sequence.
ACCESSION   DAMJYN010000090 DAMJYN010000000
VERSION     DAMJYN010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14224)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14224)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14224
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.094"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(41..997)
                     /locus_tag="PC466_003030"
     CDS             complement(41..997)
                     /locus_tag="PC466_003030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CorA family divalent cation transporter"
                     /protein_id="HDF2770392.1"
                     /translation="MYILNLNTRETIEDFRDKFYVAENSYLILSAPKNLKLLKETLDI
                     DEITFNDCLKFDEITKLDLFDNYDFLSLNTFELRDGEAVIEEVNMYLSDNFILVVVNE
                     EHFLFEFVKNIILKNSQLEKNPVINLFKINYLILREVIKNGFESLEKVEELILQIEDE
                     MMDNINKNHVSRISDVRGLTRIIVKNTRPLLYIGDRIVKENIRYLKYSNVKKYNLENF
                     QGIDFGIDKLYNFALSTRELADKLLDIYSSRVGEKTNNLITKLTLLTAISAPLTIITG
                     IYGMNFRYMPELNWIYGYPATLFFMLCIIFIGIIIFKIKKLL"
     gene            complement(1336..2034)
                     /locus_tag="PC466_003031"
     CDS             complement(1336..2034)
                     /locus_tag="PC466_003031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2770393.1"
                     /translation="MSKKLILLVEDDKTIRKFISTALLTQDYDVKEAITGKEGISIAV
                     SYSPDVVLLDLGLEDMDGIEVIKAIRQFSNIPIIVVSAREQDRDKVEVFDAGADDYLT
                     KPFSIVELLARVRVAFRHSQVEAQQKDDVKSTFEVDKLLIDFDKRKVIVDDVEVHLTP
                     IEYNILSLLAKHHGKVLTHNFIIKEIWGSVIGNETKSLRVFMATLRRKIEKQPANPRY
                     IITEVGVGYRLNDE"
     gene            complement(2068..4770)
                     /locus_tag="PC466_003032"
     CDS             complement(2068..4770)
                     /locus_tag="PC466_003032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase KdpD"
                     /protein_id="HDF2770394.1"
                     /translation="MDRPNPDILLEKIKNEEEKLSRGQLKIFFGYAAGVGKTYSMLES
                     AQNLKKVGVDVVVGYIEPHTRPETLALLDGLEILPVKEIEYKSIKLKEFDLDAALARK
                     PEVILVDEFAHSNVAGLRHTKRWQDIEELLLAGINVYTTVNVQHLESLNDIVEVITNV
                     SVKETIPDKFLDTNTQLELIDVEPDVLLERFNEGKIYKKEQATRAKNNFFIKDNLVAL
                     REIALRKTAERVNKEVQMTRLSKGDVTVIPTSDTLLACISPSPSSAKVIRTASRISDS
                     TFAKWIALYVETPNTARLPFDEQKQLQNNLKLAKKLGGEIIVLHGENIIEQILRIAKL
                     RNVTKIVIGRNHSSNKRFSKRFKKDIVDKLIDEVDYIDIHIIPYKFASDVKYKPKKDK
                     SSIKSKFKISKVDFIKLIFITLMISILAYAVQSMGFIRENILLIYMLGVVLVSMWTKG
                     YSTGIISSVFNIVLLNYFFTAPLYTLSIADSNYIVTLVVFSIVGIITSTLTSKIQHEA
                     ETAAKREENTKMIYQIIKGFLRLSSKDDIVNKGIELLSLSLSRDVICYLNVDKHNKSK
                     LYKKNTNNKDKNDLDSEDEKAVASWVLSNSTVAGNDTDTLPGSKGYYIPIVGMNLTLG
                     VVGISCIDSKLDTEDISLIETIIAQMAIALDREILSEAKENTNLEIERERLRSNLLRA
                     VSHDLRTPLAGISGAVSTIIKNKGTIGQDIIDELLSGVYEDTQWLIRLVENLLSMTKI
                     DEGKLEVKKHSELVEEIISEALQKIKKRIENALIDINIPEQILFVPMDAKLIEQVLIN
                     LIDNSLKYSKEDCKIEINVYEKDDYVWFEVSDNGPGISKELKKHIFDRFFTGEEGAKD
                     SRKGVGLGLSICKSIIQAHKGEIMVENNKDKGSTFKFSLPKENE"
     gene            complement(4948..6765)
                     /gene="ftsH"
                     /locus_tag="PC466_003033"
     CDS             complement(4948..6765)
                     /gene="ftsH"
                     /locus_tag="PC466_003033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HDF2770395.1"
                     /translation="MDEHKPQKRSALYYYTVIIIVVMFLNALIFPSLMDKKMVEIDYG
                     KFLTMLDTGKVKSVEIENNRIAINPSSSKDKNIYITGRMDDPELVDRLKNAKVEFTKV
                     IPKENSPLLSILLTWIIPIGILMLFGNLMMKSMQKRMGGNAMQFGKSNAKMYVSAQSG
                     KRFNDVAGQDEAKEALTEIVDFLHNPEKYKKIGAQMPKGALLVGPPGTGKTLLAKAVA
                     GEANVPFFSISGSEFVEMFVGMGASRIRDLFKQAKEKAPCIVFIDEIDTIGKKRDNGS
                     GLGGNDEREQTLNQLLSEMDGFDGGIGVVILAATNRPDSLDKALLRPGRFDRRIPVEL
                     PDLGGREAILKVHAQNVNVSSDIDYNAIARSTSGASGAELANIVNEAALLAVKSGRDI
                     VEQQDFDESVETVIAGYQRKGAVISDKEKKIIAYHEIGHALVAAMQKHSAPVHKITII
                     PRTSGALGYTMQVAEDESVLMSKEEAIDKITTFTGGRAAEEVIFNTCTSGASNDIEQA
                     TKIARAMVTRLGMSEEFDMVALETVSNQYLGGDTSLACSSDTAAKIDEEVFKIVKACH
                     KNAIEILENNIDKLHELANYLLEKETITGDEFMEILNLN"
     gene            complement(6796..7239)
                     /locus_tag="PC466_003034"
     CDS             complement(6796..7239)
                     /locus_tag="PC466_003034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF2770396.1"
                     /translation="MDEMSFKKELLELTRDINMKFTTLLSDFYQPLGITAVQALILSE
                     LCEHGEKKISDLGKNLNMTNSNVSVICQRLEKNGFLNRIRDIEDQRIVKVKVTNKSLD
                     IQEHISSSIFDSYFENMTSEKLQDMEDIIEGLEKLNKLLTYIDCK"
     gene            complement(7730..8620)
                     /gene="metA"
                     /locus_tag="PC466_003035"
     CDS             complement(7730..8620)
                     /gene="metA"
                     /locus_tag="PC466_003035"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HDF2770397.1"
                     /translation="MALILPKGLPVINKLLDEGIDVIYKEDFKKELKYEENIDTKIAI
                     LNLMPIKIDTELDLLRRIDKTGFNVSVEFIKISTRESKRSCNEYVKEFYKTFDEAKGE
                     YFDGFIITGAPVEQMEFEEVDYWNELEEIMDYSKRKTKSTLYICWAAQASLYKYYNVK
                     KLPLSQKCFGVFKHKVDKDSKIVDGFENEFFAPHSRHTTVNIEALKENKELSIVSHSK
                     EAGPYIITNSRDVFVMGHSEYDKYTLDKEYKRDINKGDKISIPQNYYINDDPSEEPTV
                     KWKKHSELLFRNWIKNYLIQ"
     gene            complement(8650..9915)
                     /locus_tag="PC466_003036"
     CDS             complement(8650..9915)
                     /locus_tag="PC466_003036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
                     /protein_id="HDF2770398.1"
                     /translation="MYNKETICVQGNYKPGNGEPRVLPLYQSTTFKYSSIDQLAELFD
                     LKVDGHIYSRISNPTIQAFEEKISLLEGGVSSVAVSSGQSANMLAVLNICKSGDSILC
                     SSKVYGGTFNLLGPSLKKFGIDLISFDLDSSEDEIVELAKENTKVVFAETLANPTLEV
                     IDFEKIANVAKRINVPFIVDNSLASPVLCNPLKYGANIVTHSTTKYLDGHASSVGGII
                     VDGGNFNWDNGKFPELVEPDPTYHGISYTQKFGNAAYATKARVQLLRDYGNCLSPFNA
                     YLTNLNVETLHLRMERHSENALKIARFLEKHENVDWINYPGLEDNKYYENAKKYLSRG
                     CSGVLSFGVRGGLENAKKFVEKLQIASLVTHVSDVRTCVIHPASTTHRQLTEEQLIAS
                     GVLPSLIRLSVGIENVEDLIADLNQALNF"
     regulatory      complement(10025..10127)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            complement(10181..12838)
                     /locus_tag="PC466_003037"
     CDS             complement(10181..12838)
                     /locus_tag="PC466_003037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HDF2770399.1"
                     /translation="MENHKQMPWHSRATHEILESLDSSEEGLTDTEAEKRLKENGLNE
                     LRKKPPRTTLQMLWSQITDAMVMILIGAAILSLIFGEFTEAFVILIIVTVNAVIGIVQ
                     EKKAESSLEALKNMNSPTARVMRDGEENVIPASNLVVGDIVFLEDGAMVPADLRLIET
                     SSLKIQEASLTGESVPSEKDADTILPKECVLGDRSNMAYTSSIVTYGRGVGVVVATGM
                     DTEVGNIAHLLDSQDDFDTPIKRKLNTVGKTLSVIGIIVCVVIFAIGAFYQRPLLPMF
                     MIAISLAISIIPEGLPATATIVMALGVQRMAKRNALIRKLPAVETLGGATVICCDKTG
                     TLTLNKMTVTHIAVNGDFESGKVTSIDTASEKHPLVYKEIVYAGALCNDACINPDKTD
                     EILGDPTEGALIFMAKKFGIDQEALEEEYPRVFEQPFDSDRKCMTTVHNIDEKIIAYT
                     KGAVDEILDLCTKILTSKGERNITEVDKKNIHELCLNMSKDALRVLGFAKREISSIPK
                     EDSENIEYDLTFIGMVGMIDPPRTEVIDAVSTCKEAGIRTIMITGDHKVTATTIAHEL
                     GIWSEENTVISGDELDNFSDDELDEAVKNTTVFARVSPFDKLRIIQSLKRIGEVPAMT
                     GDGVNDSPALKSADIGIAMGISGTDVAKDSSDMILMDDSFTTIAYAIKEGRRVYRNIQ
                     KVIQFLLVGNIAEILTLFVAILLNWDTPLLAVHILWVNLATATLPALALGVDPPSRNI
                     MKHQPVKSTTLFEKNLIQRVVTQGIFVAIMTILAYKIGLNIENHSVGQTMAFCVLAFS
                     QMLRAFSQRSNTDSMFNRNNGKNPFLLISFLTSAFLIAVILFVPVFRNAFNLTVLNNL
                     EWLITIVLAIMSVIQVEVGKIIKRKKRKK"
     gene            complement(12966..13709)
                     /gene="yaaA"
                     /locus_tag="PC466_003038"
     CDS             complement(12966..13709)
                     /gene="yaaA"
                     /locus_tag="PC466_003038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HDF2770400.1"
                     /translation="MIIMLSPAKNMKNIEVFDRDLSLPCFIDNTKEIVENIKTFGIED
                     FKNKMKINEKLAVLNKNRFESIKFDRLGNPAILTYDGIQYKNIEAENFTRKDEEFANS
                     CIRIISGLYGVVKPYDSIYEYRLEMQTKLRVGEFKNLYEYWGNRIYKELIKEKTAIIN
                     LSSNEYSKSIEKFIKDSDTYITCTFKVNKNGILKVESTQAKKARGMMTKYIVKNRIRD
                     IEELKKFNLEGYKYKENLSNNSEYIFVKE"
     gene            complement(13719..14183)
                     /gene="bcp"
                     /locus_tag="PC466_003039"
     CDS             complement(13719..14183)
                     /gene="bcp"
                     /locus_tag="PC466_003039"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002586316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-dependent thiol peroxidase"
                     /protein_id="HDF2770401.1"
                     /translation="MLSIGTKAPEFTLEDKDGNKVSMSDFKGKKVVVYFYPKDNTPGC
                     TRQACAFRNAYDGFKKEDIQVIGISKDSIKSHQKFAEKHELPFILLSDPDLVAIKAFD
                     VWKEKKMYGKTALGVVRATYIIDENGIIEKVFEKAKPDTNAQEILEYLEKQE"
BASE COUNT         4454 a         2556 c         1603 g         5611 t
ORIGIN      
        1 tgatgtattt ttataaaatc aattaaacat catctgtaat ttacaataat ttttttattt
       61 taaatattat aattccaata aaaattatac atagcataaa aaataaagtt gctggatatc
      121 cataaatcca gtttaattct ggcatatatc taaagttcat tccatatata ccagttataa
      181 ttgtaagtgg tgctgatatg gctgttaaca aggttaattt tgtaattaag ttatttgttt
      241 tctcacctac tctggaagaa taaatatcta ataatttatc tgctaactct cgtgttgaca
      301 atgcgaaatt gtataatttg tcaattccaa aatctatacc ttgaaaattt tctaaattat
      361 atttttttac atttgaatat tttaaatatc ttatattttc cttaactatt ctatccccaa
      421 tatacaaaag aggtctagta ttcttaacta taattcttgt taatcctctt acatcactta
      481 ttctagatac atgattctta ttaatgttgt ccatcatttc atcttctatt tgaagaatta
      541 actcttcaac tttttccaaa gactcaaaac cattttttat aacttctcta agaatcaagt
      601 agtttatctt aaatagatta ataactggat ttttttcaag ttgagagttc ttcaaaataa
      661 tattttttac aaattcaaat aaaaagtgtt cttcattcac tacaaccaat ataaaattat
      721 ctgataaata catatttact tcttctataa cagcttctcc atctcttagt tcaaatgtat
      781 ttaggcttaa aaaatcgtaa ttatcaaata aatcaagttt ggttatttca tcaaatttaa
      841 gacaatcatt aaaagttatt tcatctatat ccaaagtttc cttaagcaat tttaaatttt
      901 ttggagcact taatataaga taagaatttt ctgctacata aaatttatct ctaaaatctt
      961 caatagtctc tcttgtattt aaattcagta tatacataca tctactccta aatttcaatt
     1021 tacattctaa aaatttttta taatccttac tgtaattatt ttacactatt ttaacaatta
     1081 ttatttaata tttacattaa atttattata aggtaagtgt taaatacatt tattatttaa
     1141 ccaaagtttt tattacagat tacactatat acttatttta aaacatattt catattattg
     1201 atactaaaaa gctaaaaaat aaaatgcatg tgctaaactg acaacaagca catacacttc
     1261 attcttattt taactaaact atataatttt aatatatatt aataagcaca taatctaata
     1321 attaatatat tacaactatt catcatttaa tctgtatcct acaccaactt ctgtaattat
     1381 atatcttggg tttgcaggtt gtttttctat ttttcgtctt aatgttgcca taaagaccct
     1441 taaagactta gtctcattcc ctataacact accccatatt tcttttatta taaaattatg
     1501 agtaagcact tttccatgat gctttgcaag taatgaaaga atattatatt caataggtgt
     1561 caaatggact tcaacatcat caacaataac ttttctttta tcaaaatcaa tcaataattt
     1621 atctacttca aacgtagatt taacatcatc tttttgttga gcttctactt gtgaatgtct
     1681 aaatgcgact cttactcttg ctaataactc tactatggag aatggttttg ttaagtaatc
     1741 atctgcccct gcatcaaata cttctacctt atctctatct tgctctctag ctgaaactac
     1801 aattattggt atatttgaaa attgtctgat agcttttatt acctctattc catccatatc
     1861 ttctaagcct aaatctaaaa gaacaacatc tggagaatat gagacagcaa tagatatacc
     1921 ttcttttcca gttatagcct ccttgacatc ataatcctgt gttaaaagtg cagtagatat
     1981 aaattttctt attgtcttat catcctctac taacaatata agttttttac tcatttcttc
     2041 ctccaaaact aattttaaaa tttaaaacta ttcattttcc ttaggcaaac taaacttaaa
     2101 agttgaaccc ttatctttat tgttttctac cataatttca cctttatgag cttgaattat
     2161 agatttacaa attgataatc caagtccaac accctttctg gaatctttag ctccttcttc
     2221 tccagtaaaa aatctgtcaa agatatgctt tttaagttcc tttgatatac caggaccatt
     2281 atcagatact tcaaaccaaa cataatcatc tttctcgtat acatttatct ctatcttaca
     2341 atcttccttt gaatatttca aagaattatc tattaaatta attaaaactt gttctattaa
     2401 ttttgcatcc ataggaacaa ataatatctg ttctggtata ttaatatcta taagtgcatt
     2461 ttcaattctt ttttttattt tttgtaacgc ttctgatata atttcctcaa ccagttcaga
     2521 atgtttttta acttccaatt tcccttcatc tatcttggtc atactaagta aattttcaac
     2581 aagtcttatt aaccactgag tatcttcata tacaccacta agtaattcat ctattatatc
     2641 ttgacctata gtacccttgt tttttataat tgtacttact gcaccagata ttcctgctag
     2701 tggagttcta aggtcatgcg aaactgctct taaaagatta cttcttaatc tttccctttc
     2761 aatctcaaga ttggtatttt ctttagcttc tgacaagatt tctctatcaa gcgctattgc
     2821 catttgagca attattgttt caattaagct tatatcttct gtatccaatt ttgaatcaat
     2881 acatgatatt cctactactc ctaaagttaa attcattcct acaattggta tatagtatcc
     2941 ctttgaacca ggaagtgtat ccgtgtcatt tcctgccact gttgaattgg ataaaaccca
     3001 acttgcaaca gctttttcat cttcactatc caaatcattt ttatccttat tattagtatt
     3061 ttttttgtaa agttttgatt tattatgctt atctacattt aaataacaaa ttacatctct
     3121 acttaagcta agagacaaaa gttctatacc tttgtttact atatcatctt tacttgataa
     3181 tcttaaaaat cccttaatta tttgatatat catttttgta ttttcttctc ttttagcagc
     3241 agtttctgct tcatgctgta tcttagacgt aagagtgcta gttattatac ctactattga
     3301 gaatacaacc agtgttacta tatagtttga atctgctata gataatgtat ataatggtgc
     3361 tgtaaaaaaa taatttaaaa gaactatatt aaatacagaa cttattatac ctgtactata
     3421 ccctttagtc cacatagaaa ctaaaactac acccaacata tatattaaca atatattttc
     3481 tcttataaat cccatgcttt gtactgcata tgctaaaata cttatcatca aagtaataaa
     3541 tataagtttt ataaaatcaa ctttgctaat tttaaattta gattttattg atgatttatc
     3601 ctttttaggt ttgtatttaa catctgaggc aaatttatat ggaattatat gtatatctat
     3661 ataatcaact tcatcaatta atttgtcaac tatatctttt ttaaatcttt tactaaatct
     3721 tttattactt gaatgatttc tacctattac aatttttgtt acatttctca gttttgcaat
     3781 tctaagtatt tgctctatta tattttcacc atgtaaaaca attatttctc cacctaattt
     3841 cttagctaat tttaggttat tttgtagttg tttttgttca tcaaatggaa gtcttgctgt
     3901 gtttggagtt tcaacatata aagctatcca ttttgcaaat gtactgtctg atattctgga
     3961 tgcagttcta ataacttttg ctgaagatgg agatggactt atacatgcaa gaagtgtatc
     4021 tgatgtaggt attacagtta catcaccctt tgatagtctg gtcatttgaa cttctttatt
     4081 aactctctct gctgtttttc taagtgcgat ttctctaagt gcaaccaggt tatcttttat
     4141 aaaaaaatta ttttttgctc tagtagcttg ttctttctta tatatcttac cttcattgaa
     4201 cctttcaaga agtacatcag gttcaacatc tataagttct aactgtgtat ttgtatccaa
     4261 aaacttatct ggtatagtct ctttaactga tacgtttgta attacctcaa caatgtcatt
     4321 tagactttct aaatgttgta catttacagt agtgtagaca tttatgcctg ctaacagcaa
     4381 ttcttctata tcttgccatc tttttgtatg ccttaaccca gcaacattag aatgggcaaa
     4441 ttcatctact aatataactt ctggttttct tgctaaagca gcatctaaat caaattcttt
     4501 tagttttata gatttatatt ctatctcctt tacaggaaga atttccaagc catcaagtag
     4561 agccaatgtt tctggtctag tgtgtggttc aatatatcca actactacat ctacacccac
     4621 tttttttaaa ttttgtgcag attccaacat agagtaggtt tttcctactc cagctgcata
     4681 accaaagaat atttttaatt gacctctact tagtttttct tcttcatttt taattttttc
     4741 taatagaata tcaggattag gtctatccat taaaaaacct ccttacacca ttcattacta
     4801 ttataatatc aattccgata taaaattgta gttaagatgt atttttaatg attaagatta
     4861 tgtaaagatt taaatatgaa tttaaaaaat ttagttgtaa aataaaaatg cctaacaata
     4921 ggcattttta tcttgtgtat aatcatttta gtttaagtta agtatttcca taaactcatc
     4981 acctgtaata gtttcttttt ctaataaata attagcaagt tcatgcaatt tatcaatatt
     5041 attttctaag atttcaattg catttttgtg acaagccttt actattttaa atacctcttc
     5101 atctatttta gcagcagtgt cggaagaaca agcaagagaa gtatctcctc ctaaatattg
     5161 attgcttaca gtttcaagag cgaccatatc aaactcttca ctcataccaa ggcgagtaac
     5221 catagctctt gcaattttag tagcttgttc tatatcattt gatgctcctg atgtacaagt
     5281 gttaaagata acctcttcag cagcacgacc acctgtaaaa gtagttattt tatcaattgc
     5341 ttcttcttta gacataagta cactctcatc ttcagcaact tgcatagtat atcccaatgc
     5401 tcctgaagtt ctaggtatta tagtaatctt atggacaggt gcagaatgtt tttgcatagc
     5461 agcaacaagt gcatgaccta tttcatgata tgctataatt ttcttttcct tatctgaaat
     5521 tacagctcct ttacgttgat acccagcaat tacagtttca acagattcat caaaatcctg
     5581 ttgttctact atatctctgc cagacttaac tgctaaaagt gctgcttcgt ttacaatatt
     5641 tgcaagttct gcacctgatg ctcctgatgt agaccttgca attgcattat aatctatatc
     5701 tgagcttaca tttacatttt gagcatgtac ctttaatata gcttcacgtc ctccaaggtc
     5761 tggaagttca actggtatac gtctatcaaa tcttcctgga cgaagtaatg ctttgtcaag
     5821 actgtcaggt ctatttgtag cagcaagtat tactactcca attccaccat caaaaccatc
     5881 catctcactt aacaactgat ttaaagtttg ttcacgttca tcatttccac ctaatccact
     5941 tccattatca cgctttttac caatagtatc aatctcatct ataaacacta tacatggagc
     6001 tttttctttt gcttgtttaa ataaatcacg aatcctagaa gctcccattc ctacaaacat
     6061 ctcaacaaac tcagaaccag atattgagaa aaatggtaca tttgcttcac ctgctacagc
     6121 ttttgcaagg agtgtttttc ctgtacctgg aggtcctact aaaagtgctc ctttaggcat
     6181 ttgtgctcct atctttttat acttttctgg attgtgtaag aaatctacta tttcagttaa
     6241 agcttctttt gcctcatctt gaccagctac atcattaaat ctttttccac tttgagcaga
     6301 tacatacatt ttggcgttgc tttttccaaa ttgcatagca ttaccaccca ttcgcttttg
     6361 catagacttc atcattaagt taccaaatag cataagaata cctataggta ttatccatgt
     6421 aagtaaaata cttaaaagag gtgaattttc cttaggaata accttagtaa attctacttt
     6481 tgcatttttt agtctatcta ccaattctgg gtcatccatt ctaccagtta tgtatatatt
     6541 cttatccttg ctactagatg gatttattgc tattctatta ttttctatct caacagattt
     6601 aacctttcct gtatccaaca ttgtgagaaa ctttccatag tcaatctcaa ccattttttt
     6661 atccattaaa cttggaaata ttaaagcatt taaaaacatt actactatta ttataactgt
     6721 ataataatag agtgctgacc ttttttgggg tttatgttca tccataattt tattctcctt
     6781 taaattattt ttatgttatt tgcaatcaat gtaagttaaa agtttattta atttctctaa
     6841 accttctatt atatcttcca tatcttgcaa tttttcactg gtcatatttt caaaataact
     6901 atcaaaaata ctacttgaaa tatgttcttg tatatccaat gatttatttg taacttttac
     6961 ttttacaatt cgttggtctt ctatatctct tatgcgattt aaaaagccat ttttttcaag
     7021 cctttgacag attactgata cattactatt tgtcatgttt aagttcttcc ctaaatcgct
     7081 tatttttttc tctccatgtt cacataactc agataaaatc aaagcttgca ctgctgtaat
     7141 accaagtggc tgataaaaat cacttaataa agttgtaaat ttcatattta tatctctagt
     7201 caactctagt agctctttct taaaactcat ctcatccata caaacgctcc ctacgaaaat
     7261 actttatttc aaatttaggc tgaagtgcat actgtaaata aatacttaat actataatgt
     7321 ttaatgtatt aaatattata gtattaagta tttattgtca attacaatat tgtaacttca
     7381 attggaattt tgttatctta ttgatattta attttataca ggatattttt aataaaattt
     7441 aataaaaaat cgatatatat attttacact gatttctccc tttttaatct cttttaaaag
     7501 ttaaaataca aatttattga tactataaag gtttagtctc ccattatcgc accatatata
     7561 aaattaaaac cacctctatc tacatacacc taaagtgatt ttcttaaaat ataaaactac
     7621 tattataagg ttaaatttaa aaaaaataag gtataaagta tcattaagat taactttata
     7681 cctataaatt tctatatttt tttagttaac atttatatac tcttaaaatt tattgtatca
     7741 aatagttttt tatccaattt ctaaacaaca attctgaatg ttttttccat tttacagttg
     7801 gctcttctga agggtcatca ttaatatagt aattttgagg tatagatatt ttatctcctt
     7861 tatttatatc cctcttatat tctttatcaa gagtgtattt gtcatactcg ctatgaccca
     7921 ttacgaacac atctcttgaa tttgtaatta tatagggacc agcttcttta gaatgactca
     7981 caatgctcaa ctctttattc tctttcaaag cttcaatatt tacagtagta tgtcttgaat
     8041 gtggagcaaa aaattcattt tcaaatccat ctactatttt actatcttta tctaccttat
     8101 gcttaaatac tccaaaacat ttttgactta gtggaagttt ttttacattg tagtatttgt
     8161 aaagacttgc ttgagctgcc caacatatat ataatgtaga tttagttttt ctcttagaat
     8221 aatccataat ttcttctagt tcattccaat aatcaacttc ttcaaactcc atttgttcaa
     8281 ctggagctcc tgttattata aagccatcaa aatactctcc tttggcttca tcaaatgttt
     8341 tataaaattc tttaacatat tcattacaac ttcttttact ttctcttgtt gaaattttaa
     8401 taaattcaac agacacgttg aatcctgttt tatctatcct tcttagtaaa tctaattctg
     8461 tatctatctt tataggcatt agatttagta tagctatttt agtgtctatg ttttcttcat
     8521 actttaattc ctttttaaaa tcttctttat aaattacatc tattccttca tctaataatt
     8581 tattaataac aggtaatccc tttggtagta ttaaagccat atcttttcac ttctctttct
     8641 cttagaatat tagaaattta aagcttgatt taaatcagct attaaatcct ctacattttc
     8701 tattccaaca gataatctta ttagtgaagg caatactcca gatgcaatta attgttcttc
     8761 tgttaattgt ctatgagtag ttgaagctgg atgtataaca caagttctta catctgaaac
     8821 atgtgtaacc aaagatgcta tctgtaattt ttccacaaat tttttggcat tttctaaccc
     8881 acctcttact ccaaatgata aaacaccact acatcctctt gataaatact ttttggcatt
     8941 ctcataatac ttgttatctt caagtcctgg gtaattaatc caatctacat tttcatgttt
     9001 ttctaaaaat ctagctattt taagtgcatt ttcactatgt ctctccattc taagatgtag
     9061 tgtttcaaca tttaaattag taagatacgc attgaatggg cttaaacaat ttccatagtc
     9121 tctaagcaac tgaactcttg ctttagttgc atatgcggca tttccaaatt tttgagtata
     9181 gcttattcca tgatatgttg ggtctggctc aactaattct ggaaattttc cattatccca
     9241 gttaaagttt ccaccatcca ctataattcc tccaacactt gaagcatgcc catctaaata
     9301 ttttgtggta gaatgagtaa ctatatttgc tccatacttt aaagggttac aaagcactgg
     9361 agatgctaat gaattatcaa caataaatgg aacattaatt ctcttagcta catttgctat
     9421 tttttcaaaa tctatgactt caagagtcgg atttgcaagt gtttctgcaa atacaacctt
     9481 agtattttcc tttgcaagtt ctactatctc atcttcactt gaatctaagt caaacgatat
     9541 taaatctata ccaaattttt taagactagg tcctagtaaa ttgaatgttc ctccatatac
     9601 ttttgaagaa caaagtatac tatctcctga tttacatata tttaaaactg ccaacatatt
     9661 tgcagattgc cctgatgata cagctacaga agatactcca ccctctagta aacttatttt
     9721 ttcttcaaaa gcttgaatag taggattgct tattcttgaa tatatatgtc catcaacttt
     9781 taaatcaaat aattcagcaa gttggtctat actgctatat ttaaaagttg tactttgata
     9841 taaaggtaat actcttggtt ctccattacc tggtttataa tttccttgca cacatattgt
     9901 ttctttatta tacattcttg tatccccctt agattttagt aaaaaaaatt aaactattta
     9961 tcagatgaga gttaaaataa ataaagcctg agtatataac tcaggctctg tataagctta
    10021 attatactca tctctcagct ttcgccgcag gatttagcac caatgtatat aaatatactg
    10081 gttgccgggt ttcatagggc cagtccctcc acctctctgg ataagattta tttaattttt
    10141 ctatgtttta tatcttatat atttttccta attttgtcaa ctattttttt cttttttttc
    10201 ttttaataat tttcccaacc tctacttgaa ttacagacat tatggctaaa acaatcgtta
    10261 taagccactc taagttattt aaaactgtta agttaaaagc atttctaaaa acaggtacaa
    10321 acagtattac tgctattaaa aatgcagaag ttaaaaatga gattaaaaga aatggatttt
    10381 taccattatt tctattaaac attgaatctg tatttgaacg ctgactaaat gctcgtaaca
    10441 tctgtgaaaa tgctaataca caaaatgcca ttgtttgacc tacagaatga ttttctatat
    10501 taagaccaat tttatatgct aaaatagtca ttattgccac aaatatacct tgggtaacaa
    10561 ctctttgtat aagatttttt tcaaacaaag tggttgattt cactggctgg tgcttcatta
    10621 tatttctgct tggtgggtca actccaagag caagggctgg aagcgtagca gttgcaaggt
    10681 ttacccatag aatatgaaca gcaagaagcg gagtatccca atttaataat attgctacaa
    10741 acaacgtaag tatctctgct atattaccaa caagcaaaaa ttgtataact ttttgtatgt
    10801 ttctatatac acgtctacct tcttttattg cataagcaat tgttgtaaaa ctatcgtcca
    10861 ttaaaatcat gtcagaagaa tcttttgcaa catctgtacc acttataccc atggctatac
    10921 caatatcagc agactttaag gcaggagagt catttacacc atccccagtc attgctggta
    10981 cttctccaat tctttttaga gattgtataa ttctaagttt atcaaacggg gacacacgag
    11041 caaatactgt agtattttta acagcttcat ctagttcatc atcactaaaa ttatcaagtt
    11101 catcaccaga tatcacagta ttttcttcac tccatattcc taactcatga gcgattgttg
    11161 tggcagtaac tttatggtca cctgttatca ttatggttct tatacctgct tctttacaag
    11221 tacttactgc atcaattacc tcagttcttg gtgggtcaat cataccaacc atacctataa
    11281 atgtcaaatc atattctata ttttcactat cttcttttgg tatagatgaa atctcacgct
    11341 tagcaaaacc aagtacacgc aatgcatctt tagacatgtt aagacataat tcgtgtatat
    11401 tctttttatc cacttcggta atgtttcttt caccttttga agttaatatt ttagtacata
    11461 ggtcgagaat ttcgtctact gctcctttag tataagcaat aatcttttca tctatattat
    11521 gaacagttgt catacatttt ctatctgaat caaaaggctg ttcaaataca cgtggatatt
    11581 cttcttcaag agcttcttga tctattccaa attttttggc cataaaaatt aatgcgccct
    11641 ctgttgggtc acctaatatt tcatctgttt tatctggatt aatacatgca tcattacaaa
    11701 gtgcaccagc ataaacaatc tctttataca ctaatggatg tttttcagat gcagtatcta
    11761 ttgatgtcac ttttccagat tcaaaatctc cattgacagc aatatgtgta acagtcattt
    11821 tatttaaggt taatgtacca gttttatcac aacatattac tgtagctcct cctaatgttt
    11881 caacagcagg taattttcta attaaagcat ttcttttagc catacgctgt acgcctaaag
    11941 ccattacaat agtagctgtt gcaggtaatc cctctggaat aattgatatg gcaagggaaa
    12001 ttgcaatcat aaacattggc aagagaggtc tctgataaaa tgcacctatt gcaaatataa
    12061 caacgcatac aataatacct atgacactta atgtctttcc aacagtatta agtttacgtt
    12121 ttataggagt atcaaaatca tcttgtgaat ctaaaagatg tgctatgtta cccacttctg
    12181 tatccatacc agttgctact acaacaccta cacctctacc atatgtgact attgaagatg
    12241 tatacgccat attgctacgg tctcctaata cacattcttt aggtaagatt gtatctgcat
    12301 ctttttctga tggaacagat tctcctgtta aagaagcctc ttgaattttt aaacttgatg
    12361 tttctattaa acgaaggtct gctggaacca tagctccatc ttctaaaaaa acaatatctc
    12421 ctactacaag attacttgct ggaataacat tttcttcacc atcacgcata acacgagctg
    12481 taggtgagtt catatttttt aatgcttcta atgatgattc tgcttttttc tcttgaacaa
    12541 ttccaataac tgcatttact gttacaatta ttagtattac aaaagcttct gtaaattcgc
    12601 caaatatcaa agataatatt gctgctccta ttagtatcat aaccatagca tctgtaattt
    12661 gactccaaag catttgtaaa gttgttctag gtggtttttt tctaagttca tttaagccat
    12721 tctctttaag ccgtttttcc gcctcggtat cggtgagccc ctcctctgat gaatctagac
    12781 tttctaaaat ttcatgcgtt gctcttgaat gccaaggcat ctgtttgtga ttttccattt
    12841 tggaagacca ctcctttctt tttttaattt aagaataatt atattttaaa atcaagttca
    12901 attcaataca cactaagtat attttaccta aatttaacaa tgccatttaa tatttaacaa
    12961 aacttctact cttttacaaa tatgtattca ctattgttag ataagttttc tttatactta
    13021 taaccttcta aattaaactt tttcagttct tcaatatctc ttatcctatt ttttacaatg
    13081 tattttgtca tcatacctct agctttcttt gcttgtgtag attccacttt caatatgcca
    13141 tttttattta ctttaaaagt acatgtaata tatgtatcac tatctttaat aaatttttct
    13201 atggacttgc tgtattcatt tgatgaaaga ttaatgatag ctgttttttc tttgattagt
    13261 tctttatata tacgatttcc ccaatattcg tataaattct taaactcacc tactcgtaat
    13321 tttgtctgca tttctaatct atattcatat atactatcat atggttttac aacaccatac
    13381 aatccactta tgattcgaat acagctattt gcaaactctt catctttcct tgtaaaattt
    13441 tctgcttcta tatttttata ttgtattcca tcataagtta agattgcagg gtttcctaat
    13501 ctatcaaatt taatgctttc aaatctattt ttatttaata cagctaattt ttcattaatt
    13561 ttcattttat ttttaaaatc ttctatacca aatgtcttta tattttccac tatttctttt
    13621 gtgttatcta taaaacaagg caaactcaaa tctctatcaa atacttctat attcttcata
    13681 tttttagctg gtgataacat tataatcata aattcttatt actcctgttt ttccaaatat
    13741 tcaagaatct cttgtgcatt tgtgtctggt tttgcttttt caaagacttt ttcaataatt
    13801 ccattttcat ctataatata tgtcgcacgt acaactccca atgcagtttt tccatacatt
    13861 tttttctctt tccatacatc aaaagctttt atagcaacta agtcagggtc agaaagtaaa
    13921 ataaaaggaa gttcatgctt ttctgcaaat ttttgatgtg attttatact atctttactt
    13981 atcccaataa cttgtatatc ttccttttta aatccatcat atgcatttct aaaagcacaa
    14041 gcttgacgtg tacatcctgg tgtattatct ttaggataaa aatatactac tacttttttg
    14101 cctttaaaat ctgacatact taccttattt ccatctttat cttctagtgt aaattctggt
    14161 gcttttgttc ctatactcaa cataaatatc tctccttttg tttttattaa taattttata
    14221 ctat
//
LOCUS       DAMJYN010000091        14045 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.095, whole genome shotgun sequence.
ACCESSION   DAMJYN010000091 DAMJYN010000000
VERSION     DAMJYN010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14045)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14045)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14045
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.095"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            434..1327
                     /locus_tag="PC466_003040"
     CDS             434..1327
                     /locus_tag="PC466_003040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfide/dihydroorotate dehydrogenase-like
                     FAD/NAD-binding protein"
                     /protein_id="HDF2770402.1"
                     /translation="MSNKIVSKRQLTDSIYLMEIEAPRVAKSSQPGQFIIIKNDEKGE
                     RIPLTIADYDREKGTVTIVFQTVGASTKKLAMFEENDFVMDFVGPLGQASEFIHEDIE
                     ELRNKKILFVAGGVGSAPVYPQVKWFKEHGLDVDVIIGARTKELIILEDDMKKVAKNV
                     YVSTDDGTYGFNGRVTDLLKDLVDNQGKKYDQAIVIGPMIMMKFMCQLTKELNIPTIV
                     SLNTIMIDGTGMCGGCRVSVGNETKFACVDGPEFDGHLVDFDQAMRRQSMYKTQEGRA
                     ILKLEEGDSHHHSNCGCGGNK"
     gene            1327..2721
                     /gene="gltA"
                     /locus_tag="PC466_003041"
     CDS             1327..2721
                     /gene="gltA"
                     /locus_tag="PC466_003041"
                     /EC_number="1.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent glutamate synthase"
                     /protein_id="HDF2770403.1"
                     /translation="MDAKKVKVPVREQEPAVRATNFDEVCLGYNKEEAMAEANRCLAC
                     KKPKCVGGCPVGIDIPGFITKIKEDDIEGAAKVIAKSSSLPAVCGRVCPQESQCEGVC
                     ILGIKSDAVSIGKLERFVADWSKENDINLSDTEPKKNQKVAVIGSGPAGLACAGDLAK
                     KGYDVTIFEAMHEPGGVLTYGIPEFRLPKQAVVQPEIDNIRKLGVKIETNVIVGKTIT
                     VDELIEDEGFEAIFIGSGAGLPMFMNIPGENANGVFSANEFLTRVNLMKAYRDDYDTP
                     ISSGKKVAVVGGGNVAMDAARTALRLGSESYIVYRRSEKELPARAEEVHHAKEEGIIF
                     NTLTNPKEILVDENGYVKGMVCIRMELGEPDDSGRRRPIEIEGSEFVLDVDTVIMSLG
                     TSPNPLISSTTKSLNINKKRCLITDENGQTSKEGVFAGGDAVTGAATVISAMGAGKTA
                     AASIDEYLKTKVNA"
     gene            3087..5306
                     /locus_tag="PC466_003042"
     CDS             3087..5306
                     /locus_tag="PC466_003042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDF2770404.1"
                     /translation="MKKREKVFDGLVFKHILILLILLVLIDLTSTIIYASNSMEITSR
                     NMIEASKRELENYLEVNISLLKALSQDDRFSNGETSLIEKGKLLRPYQKEYNLFMIGI
                     TDTKGNASSTYRENVNSIKDKPSFEKAIKTKQVVVSDIEVSNVTGDKVFIIYVPIVKN
                     NEMIGTIFASFYFQDVNNLISRSNFDDSIKFLMIDKDYTIISHPNKKYVNDKSKMLDL
                     EGNIIGTTKSEILKNINKKCQGDFLSWDNWRLYNVKYTNIKWTNWTLVSKCNIFKNFK
                     NLIVNFMIKLYFYIVIFMILWKLSNAKLIEQLKKLAYYDSLSGIKNKEKFRKDSMYIL
                     KNYYQDNFYLVQLDVNKFKYINEMFGYAEGNKILIHISQVLNNNTNKYEICARMDNDH
                     FILLIACNTEDELLNRLSKINKEICNLNTTNSSKYKIVMSSGIYKITKKDDIKKIDLL
                     IDRANIAAKSKKEKYEHSYSFFNEDTRNRLYKEKRLEDNMNKALEKGEFIVYYQPKYS
                     LDDVNEIEGAEALIRWNSPEFGFISPIDFVPLFEKNGFIVNIDMFVFEEVCKTLNKWI
                     NKGYTPVPISVNMSRVHLYRDNFIENITDLISKYNISPEFIELELTESVVFDNLNILI
                     DIMKKIKEIGFLISMDDFGSGYSSLNLLKDLSFDILKLDRGFLIETTDTKRGKIIISK
                     IVEMAKAIDIKVICEGVETYEQVEFLKEIGCDKVQGYLFAKPMVLDEFEKHLNFKFD"
     gene            5453..6199
                     /locus_tag="PC466_003043"
     CDS             5453..6199
                     /locus_tag="PC466_003043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2770405.1"
                     /translation="MNILSIRNISKTYCGNIPFKALDKVSLNIEKGEFVSVMGPSGSG
                     KSTLLNIISTVDRQSEGEVVLDGYDVSKLKGEKLAEFRRKQLGFVFQDFNLIDTLTVG
                     ENIMLPLTLEGASIKDMNIQTKSISKFLGIDKILDRKTYEISGGQAQRCAIARAIINK
                     PTILLADEPTGNLDSKSTDDVLKLFTRINKEQNVTTLMVTHEVYSASYSDRVIFIKDG
                     CIYTEIKKSESSNSFYSDILAVLSQIGGVR"
     gene            6199..8079
                     /locus_tag="PC466_003044"
     CDS             6199..8079
                     /locus_tag="PC466_003044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2770406.1"
                     /translation="MDFRKFAYNNIVRNFRAYLAYFLSSVFSIMIFFVFAVSMFHPII
                     TKSGMQSGSTAFMALMTSELTILGFSLLFILYSLGNFLKYRLKDFGVLMIIGMSNRQL
                     KKLILIENLIIGFLAVMLGILLGLSISKLFLLYLSKLFYMNLTEIYFPVKAILLTIVS
                     FMILFLITGPMSLKLLRKKSILELLVGTKKPKKEIKSSRLFGIIGVICLILGYAMILF
                     GNKLKINGGMYTTALLITLGIFLFFSQFTILILKYLKNKEKFYKNKVNMLLISNLIYK
                     LKDNTRLLFLITILLSATLVAFTTTSTLVSSQGEASKNNFPMVYSYFSEHNNEKEYEE
                     LQQIREAIKGYDYKELSFPVLKYNREVLLSVKNYNKLSKELGLDKISSKLEKYEGIII
                     PSSNSQEHINSLKQLKNYSIKNLNIEVKKSKNKIIFPTGLFSKVVVISDDLYDEVKGE
                     FSKINFHGFDYKNWQSSAKITENLKEKHFNLDREYNRSYFLTLPDMYLVELQQSKILQ
                     FMGVFIGVILFIAVFSFLYFRLYTDEIEDNVKYKKLSKIGLSFKNMNKIVSIEIGTLF
                     FIPYFIAIINSIISLLFLNQVLNNSFRLENLGILLLISSIYSLYFYLLKKIYTRKVWF
                     FD"
     gene            8198..9589
                     /locus_tag="PC466_003045"
     CDS             8198..9589
                     /locus_tag="PC466_003045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF2770407.1"
                     /translation="MENQQLLGTERISKLLLKYSIPAIIGMLVNSLYNVVDRIFIGNI
                     PGVGPLAITGLGVTMPIMTIILAFGMLIGIGTTTTISIKLGQGKVEEARKLIGNAMTL
                     SVITGIIIMILGILFANKILTLFGASENTLIYAKSYINIILLGTVVNLLSFSLNHSIR
                     ADGSPKISAGIMIVGCLTNIVLDWILIFGFNLGIQGAAIATVTSQALTAILTIGYYIS
                     GKSNLRFSKSNLKLDKKLIKAVFAIGMSPFAMQLAASLVQVISNIALKTHGGDLAIGA
                     MATISSIAMVFLMPIFGINQGAQPIIGFNYGAEKYDRVKKAYLGSLVVATIILCMGMV
                     VVMLFPEAIIGIFNKDPELMNISVNGLRIYLLMLPIVGLSVTGTNFIQSIGKAKMAML
                     LSLLRQVILLIPAVLILPTFLGLQGVWTAQPVSDFIATVITGIVVFRELKRYTPKTEK
                     LNENERLNEITTE"
     gene            9696..10736
                     /locus_tag="PC466_003046"
     CDS             9696..10736
                     /locus_tag="PC466_003046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HDF2770408.1"
                     /translation="MEFTKKSKLKNMYVNMNVARMLSKINEYKGRQLLYKKQPKEILE
                     NLEKKSLVDCSESTYIGNQRDSSNFNLEKLISNEVTPRSREELSIVEYRDVVKTINSA
                     YESIPISSQTILELHGYLYKFSSTRGGSYKSDNDFIEHNLKPSEFISIDSSVNKVEKA
                     VEEICEAYNTLIEEDEIDILILISAFVLDFILIHPFKEGNIKMARVLILLLLNKNGYE
                     VGRYISLGKIFDDSSYEYYSNLNYLKASIGSEKADMNAWIEYFLETILTAYEKLDDSL
                     NISDKKRQTKTSRIEKIINSTLGYFTKEDIRDLCPDIPEPTINRVFNNLRKQDKIEVV
                     ARGRSAKWKKKY"
     gene            11225..11878
                     /locus_tag="PC466_003047"
     CDS             11225..11878
                     /locus_tag="PC466_003047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HDF2770409.1"
                     /translation="MKKKLLYINVNSKPEDLSSSKTVARKFINKFMEKNKDFEVEEID
                     LYKEHIPRLEYQYFEKRNSIVSEENAKNLDDKDRKELTKIRNLCDQFVSASVYVIAAP
                     MWSLSFPAPLKEYIDCIIQDGKTISFEGNDKPQGILNDIDRSMVYIQSSGGHIPWVLK
                     PVMNKGLNYVESIMKFIGIKKFDELLVDGTGTSEEERQAAIEKASEKIHGIIDGMKF"
     gene            11954..12163
                     /locus_tag="PC466_003048"
     CDS             11954..12163
                     /locus_tag="PC466_003048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770410.1"
                     /translation="MREEKSNEKYDCYWCNQENNFCVEIKDNIVMIDDGTGTLKQAVF
                     IGYKQIQINLNCSHCQNLNRIKLNL"
     gene            complement(12303..12869)
                     /locus_tag="PC466_003049"
     CDS             complement(12303..12869)
                     /locus_tag="PC466_003049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HDF2770411.1"
                     /translation="MMNNELNTIILETLNNADITSNDIPSIDLYMDQIISLIDNKLSP
                     NKRFESDKILTKTMINNYSKEGLIKPVKGKKYTKEQILQMIIIYSMKNTLTIQEIKRI
                     LHGVYEKDNFSEKDLVSCYEKFMLIKENQRKNIPDFIESNFENISINPENKDDLLIAL
                     LSLTSMADQLKNISEKLVDRYFPDITKK"
     gene            13030..13683
                     /locus_tag="PC466_003050"
     CDS             13030..13683
                     /locus_tag="PC466_003050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HDF2770412.1"
                     /translation="MYQFFLKGRDPISSLTHFIGACLSLLATIILVFQSVTLQETSLL
                     MIVSVSVFGLSLIALYSASSYYHFLKGTPEQELFFRKVDHAMIYVLIAGSYTPICLNF
                     MEKKEGIIFVTAIWIVAFIGIIIKIFWMDAPRWLSTSIYLLMGWAIVFDINAFNSIPK
                     DCLRLLIMEGVSYSIGAIIYIIKKPNISPEFGFHEIFHIFIMIGSLFHFLAVLLYVL"
     gene            complement(13841..14017)
                     /locus_tag="PC466_003051"
     CDS             complement(13841..14017)
                     /locus_tag="PC466_003051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770413.1"
                     /translation="MYKYDDYVNLTNDLDLPVEIRNKCVRIVSVSENLEDIIIVHKFK
                     LYVVNEKYIKGIME"
BASE COUNT         5509 a         1387 c         2368 g         4781 t
ORIGIN      
        1 tataatatga aagctggtat tgcaatagat taaagcctta tacacgttta gtttttaaag
       61 aaattagtgt tattatgaaa acctaagtta atttattaaa taaataattg aataaaaaaa
      121 ttttattatg tatttataaa atttttgtta caaatttggc ataatatagt atactttaag
      181 tgtgtattag gttaaatcta taacaaatta gacgtatgat atagacttag tgtttattgg
      241 catttacaag aaatttgtta atatcaacta tttgtagttt gggcagttat aattactata
      301 ggggggatgt ccaatacaaa acaatcaacc aagaactaat attatattat aaagagttat
      361 agttttgtgt gtttatgttt ttaattaaat ttaaagtggg aaaaatatat ttgttagaat
      421 ggagaatagc gagatgagta ataaaatagt tagtaagaga caattaacag atagtattta
      481 tttaatggaa atagaggcac ctagagttgc aaaatcttct caaccaggtc aatttataat
      541 aattaaaaat gatgaaaagg gagagaggat tcctcttaca atagctgact atgatagaga
      601 aaaaggaaca gtaactattg tattccaaac agttggtgct tcaactaaaa agttagcaat
      661 gtttgaagaa aacgattttg taatggattt tgtagggcca ttaggacaag caagtgaatt
      721 tatacatgaa gatatagaag aattaagaaa taaaaagata ttatttgtag ctggtggagt
      781 tggttctgct ccagtttatc cacaagttaa atggtttaaa gagcatggat tagatgtaga
      841 tgtaataatt ggtgcaagaa ctaaagaatt aattatatta gaagatgata tgaaaaaagt
      901 agctaaaaat gtatatgtat caacagatga tggtacatat ggatttaatg gaagagttac
      961 agacctatta aaagatttag ttgataatca aggtaaaaaa tatgaccaag caatagtaat
     1021 tggaccaatg ataatgatga aatttatgtg ccaattaact aaagaactaa atatacctac
     1081 tatagtaagt ttaaatacaa taatgataga tggaacaggt atgtgtggtg gttgtagagt
     1141 tagtgttgga aatgaaacta agtttgcatg tgtagatggt cctgaatttg atggtcattt
     1201 agttgatttt gatcaagcaa tgagaagaca gtctatgtac aagactcaag agggaagagc
     1261 tattctaaaa cttgaagaag gcgatagtca tcatcatagt aattgtggat gtggaggtaa
     1321 caaataatgg atgctaaaaa agtaaaagta ccagttagag aacaagaacc tgctgtgaga
     1381 gcaacaaatt ttgatgaagt atgcttaggg tataataaag aagaagctat ggcagaagct
     1441 aatagatgtt tagcttgtaa aaaaccaaaa tgtgtgggtg gatgtccagt aggaatcgac
     1501 ataccagggt ttataacaaa aattaaagaa gatgatatag aaggtgctgc taaagtaata
     1561 gctaagagca gttcattacc agctgtttgt ggtagagtat gcccacaaga aagtcaatgt
     1621 gaaggtgtat gtatacttgg aataaaatca gatgctgtat caataggtaa attagaaaga
     1681 tttgtagcag attggtcaaa agaaaatgac ataaatttat ctgatacaga gcctaagaaa
     1741 aatcaaaaag tagcagtaat aggaagtggt ccagcaggtc tagcttgtgc tggtgattta
     1801 gctaaaaaag gctatgatgt aacaatcttt gaagcaatgc atgagccagg tggagtttta
     1861 acttacggaa tacctgagtt tagacttcca aaacaagctg ttgttcaacc tgaaatagac
     1921 aatataagaa aattaggtgt aaaaatagaa actaatgtaa ttgttggtaa aacaattaca
     1981 gtagatgaac ttatagaaga tgaaggattt gaagctatat tcataggttc aggagctggt
     2041 cttccaatgt ttatgaatat accaggggaa aatgcaaatg gagtgttttc tgcaaatgag
     2101 tttttaacta gagtaaactt aatgaaggct tatagagatg actatgatac acctattagt
     2161 tctggtaaaa aagttgctgt agtaggtggt ggaaatgttg ctatggacgc tgctagaact
     2221 gcattaagat taggttcaga atcatatata gtttatagaa gaagtgaaaa agagcttcca
     2281 gcaagagctg aagaagttca tcatgcaaaa gaagaaggca ttatatttaa tacattaaca
     2341 aatcctaagg aaattttagt agatgaaaat ggatatgtta aaggtatggt ttgtataaga
     2401 atggaattag gagagccaga tgattctgga agaagaagac ctatagaaat agaaggttct
     2461 gaatttgtac ttgatgtaga cacagttata atgtcacttg gaacaagccc aaatccacta
     2521 atatcttcta caacaaagag tcttaatata aataagaaga gatgcttaat aacagatgaa
     2581 aatggtcaga cttctaaaga gggtgtattt gcaggtggag atgctgttac tggagcagca
     2641 acagtaatat ctgcaatggg tgctggtaaa acagcagcag catcaataga tgaatattta
     2701 aaaacaaaag ttaatgctta atttgtaaat taaagagagg gtgtctcaaa atgaactttt
     2761 tagttcatga ggcacttttt ttgtacaaaa tcaaatatgt tttaatcatt tcaacaatga
     2821 aaatttcatt cctgtagaaa gtctaacttt taagtcttag tacaatctct attttgatgt
     2881 aggcactttt ttagatggtt taataattta tcagttatta ttgtaatatt tgatactaag
     2941 taacataact ttgtctaact atgataaaat agttatacaa taaaggtctt gtaaggagtg
     3001 aataatgtgt ggctaataaa atcagatttg tcaaatctaa cattaaataa tagaaaaata
     3061 aattgtgtaa ttaatggtat tttaatatga aaaaaagaga aaaagtattt gatgggctag
     3121 tttttaagca tatattaatc ttattaatac tattagtttt gattgattta acaagtacca
     3181 tcatatatgc aagtaactct atggaaatta cttctagaaa tatgattgag gcatcaaaaa
     3241 gagaacttga aaactattta gaagtaaaca tatctttatt aaaagctctt agtcaagatg
     3301 atagattttc taatggtgaa acatcactaa ttgaaaaggg aaaattatta aggccatatc
     3361 aaaaggaata taatcttttt atgattggta taacagatac aaaaggaaat gcttcaagta
     3421 catataggga aaatgttaac tcaataaaag ataagcctag ttttgagaaa gcaattaaaa
     3481 caaagcaagt agtagtttca gatattgaag tcagtaatgt aacaggtgac aaagtattta
     3541 tcatatatgt accaattgta aaaaataatg agatgattgg gaccattttt gcttcttttt
     3601 attttcaaga tgtaaataat ttaataagta gaagcaattt tgatgattct attaaatttc
     3661 taatgataga taaagattat actattattt ctcatccaaa caaaaaatat gtaaatgata
     3721 aaagtaagat gcttgattta gaagggaata ttataggaac cactaaaagt gaaatcttaa
     3781 aaaatataaa taaaaaatgt caaggtgatt ttttatcttg ggataattgg agattatata
     3841 atgtaaaata tacgaacata aagtggacta attggacttt agtatcaaaa tgtaatatat
     3901 ttaagaactt taaaaatcta atagttaatt ttatgataaa gttgtatttt tatatagtaa
     3961 tatttatgat attgtggaaa ttaagtaatg ctaaattaat agaacaactt aaaaaattgg
     4021 cttattatga ttctttaagt ggaataaaaa ataaagaaaa gtttagaaaa gattctatgt
     4081 atattttaaa gaattattat caagataatt tttacttagt acaattggat gtcaataaat
     4141 ttaaatatat aaatgagatg tttggatatg ctgaagggaa taagatatta attcatatat
     4201 cacaggtttt aaataataat acaaataaat atgaaatttg tgctaggatg gataatgacc
     4261 attttatatt gttgattgct tgtaatactg aagatgaact tttaaataga ttatctaaaa
     4321 taaataaaga aatttgtaac ttaaatacta ctaactcatc taagtataaa attgttatgt
     4381 caagcggaat atataagatt actaaaaagg atgatattaa aaagattgac ctgttaattg
     4441 atagagcaaa tattgcagca aaaagtaaaa aggaaaaata tgaacattca tattcgtttt
     4501 ttaatgaaga tacaagaaat cgattgtaca aggaaaaacg attggaagat aatatgaata
     4561 aagctttaga aaaaggtgaa tttatagtat attatcaacc taagtatagt ttagatgatg
     4621 taaatgaaat tgaaggagca gaagccttga taagatggaa tagtccagaa tttgggttta
     4681 tttcacctat agattttgta cctttatttg aaaagaatgg ttttattgta aatattgata
     4741 tgttcgtgtt tgaagaagta tgcaaaacat taaacaagtg gataaataaa gggtatactc
     4801 ctgtaccaat ctctgtaaat atgtctagag ttcatttata tagggataat tttatagaaa
     4861 atataactga tttgataagt aaatacaata tatctcctga gtttattgaa cttgaactaa
     4921 cagaaagtgt tgtgtttgat aatttaaata tattgattga tataatgaaa aagattaaag
     4981 agataggatt ccttatatca atggatgatt ttggttcggg atattcatct ttaaatctgt
     5041 taaaagacct ttcttttgat attttaaaat tagatagagg atttttaatc gaaacaacag
     5101 atacaaaacg tggaaaaatt attatttcta agattgtgga aatggcaaaa gcgattgata
     5161 ttaaagtaat ctgtgagggc gtagaaactt atgaacaagt agagttcttg aaagagatag
     5221 gttgtgataa ggttcaagga tacttatttg ctaaacctat ggtattagat gaatttgaaa
     5281 aacacttaaa ctttaaattt gattaatcat taataattat tagactataa tataccctaa
     5341 caacttactt acaaatatgt aagttaattg ttagggtatt tttatggtta aagtagtata
     5401 ttcacgatat tatggtattg tagtaaaaat aaaaaattat ggagaatata aaatgaacat
     5461 attgagtatt agaaatatat caaaaacata ttgcggaaat attccattta aagcattaga
     5521 taaggttagt ctaaatatag aaaagggaga atttgtgtct gttatgggac catctggaag
     5581 tggtaaatct actcttttaa atataatatc tacagttgat agacagagtg aaggtgaggt
     5641 tgtattagat ggatatgatg taagtaaatt gaaaggagaa aaacttgctg aatttagaag
     5701 gaaacaactt ggttttgtat ttcaggattt taatttgatt gacactttaa ctgttggcga
     5761 aaatattatg ttgccactta cactagaggg ggcaagtatc aaagatatga atatacaaac
     5821 taaaagtata tctaaatttt taggaataga taaaatttta gatagaaaaa cctatgaaat
     5881 ttcaggaggt caagctcaaa ggtgtgctat tgctagagct attataaata aacctaccat
     5941 acttcttgca gatgagccaa ctggaaatct tgattcaaaa tctactgatg atgttttgaa
     6001 attatttact aggataaaca aagaacaaaa tgtaacaaca cttatggtaa ctcatgaagt
     6061 atatagtgca agttattcag atagagtaat ttttataaaa gatggttgta tatatacaga
     6121 aataaaaaaa tctgaaagca gtaattcttt ctattctgat atactagctg ttttgtctca
     6181 aataggaggt gtaagatagt ggattttaga aagtttgctt ataataatat agttagaaat
     6241 ttcagggcat atttagcata ttttttaagt tctgtttttt ctataatgat attttttgtt
     6301 tttgcagtgt ctatgttcca tccgattata acaaaatctg gaatgcagag tggttctact
     6361 gcatttatgg ctcttatgac ttcagaatta acaatattag gttttagtct actttttata
     6421 ttgtactctt taggaaattt cttgaaatat agattgaaag attttggagt attgatgata
     6481 attggaatga gcaacagaca actgaaaaaa ttgatattaa ttgaaaattt gataatagga
     6541 tttttagcag tgatgttagg aatattactt ggtttatcaa tttcaaaatt gtttttattg
     6601 tatttaagca aactgtttta tatgaattta actgaaattt attttccagt aaaagcaata
     6661 ctattgacta ttgtatcatt tatgatttta tttttgataa caggaccaat gagcttaaaa
     6721 ttattgagaa aaaagagtat tttagagctt ttagtaggta caaaaaagcc taaaaaagag
     6781 ataaaatctt caaggctatt tggaataatt ggtgtaatat gtcttatatt aggatatgct
     6841 atgatactat ttggcaataa gttaaaaata aatggaggta tgtatacaac agcactatta
     6901 attactttgg ggatattttt atttttttct caatttacta ttttgatatt aaagtattta
     6961 aaaaataaag aaaaatttta taagaacaaa gtaaatatgt tacttataag taatttgata
     7021 tataaattaa aggataatac acgattgtta tttttaataa caatactttt atcggctact
     7081 ttagtagcat ttacaacaac ttcaacactt gtaagttctc aaggagaagc ttctaaaaat
     7141 aatttcccaa tggtttactc atatttttca gagcataata atgaaaaaga atatgaagaa
     7201 ctacaacaaa ttagagaagc aatcaaagga tatgattata aggagttaag ttttcctgta
     7261 cttaaatata atagggaagt cttactaagt gtaaagaatt ataacaaatt atcaaaggaa
     7321 ttgggattag ataaaattag ttcaaagtta gaaaaatatg aagggattat aattcctagt
     7381 agcaattcac aagaacatat aaattcttta aaacaattaa aaaattatag tataaaaaat
     7441 ttaaatatag aagtaaaaaa atcaaaaaat aaaataattt ttcctacagg actgtttagt
     7501 aaagttgtag ttataagtga tgacttatac gatgaagtaa aaggtgaatt ttcaaaaatt
     7561 aattttcatg gatttgatta taaaaactgg caaagcagtg caaagataac tgaaaattta
     7621 aaagaaaaac attttaattt ggatagagaa tataacaggt catatttttt aacattacca
     7681 gatatgtatt tagtagagtt acaacaaagt aaaattcttc aatttatggg tgtttttata
     7741 ggagtgatat tatttatagc agtttttagt tttttatact tcagattata tacagacgag
     7801 atagaagata atgtaaagta caaaaaacta tcaaaaatag gtctatcttt taaaaatatg
     7861 aataagattg ttagtataga gataggtaca ttgtttttta taccgtattt tatagcaatt
     7921 ataaatagca taatttcttt actgttttta aatcaagtat taaataatag ttttaggtta
     7981 gaaaatttgg gtatattact actgatatca tctatatatt cactttattt ttacttatta
     8041 aaaaaaattt atactagaaa agtttggttt tttgattaaa gtggtatata atagatatat
     8101 aaattaatat ttaaaaagta gttaatatta ggggagggca tttgcacctc ccttgtaata
     8161 tgtggaaaat tgaatattag aagaaggagg agacttgatg gaaaatcaac aattattagg
     8221 aacagaacga attagtaaat tactactaaa atattctata ccagctataa taggtatgtt
     8281 ggtaaatagt ttatataatg tagtagatag aatttttatt ggaaatatac caggggttgg
     8341 accacttgca ataacaggtc ttggtgtaac aatgccaata atgacaataa tacttgcatt
     8401 tgggatgttg ataggtatag gaactactac taccatatca ataaaacttg ggcaaggtaa
     8461 agtagaagag gcaagaaaac ttataggaaa tgcaatgacg ttatctgtaa taacaggaat
     8521 tatcataatg atacttggaa tattatttgc aaataaaata cttacattgt ttggagcaag
     8581 tgaaaatact ttaatatatg caaaatcata tataaatatt atattattag gtacagtagt
     8641 aaatcttctt tccttttctt taaaccactc aataagagct gatggtagtc ctaaaatttc
     8701 agcaggaata atgatagtag gatgtttaac taatatagtt ttagactgga tattaatatt
     8761 tggattcaat ttgggaatac aaggagctgc aattgctaca gtaacttctc aggctcttac
     8821 agctatttta actatagggt attatataag tggaaaatca aacttacgat tcagtaaatc
     8881 taatctaaaa ttagataaaa agctaataaa agcagtgttt gcaataggta tgtcgccatt
     8941 tgcgatgcaa cttgcagcaa gtttagttca agtaatatca aatattgcac ttaaaactca
     9001 tggtggagat ttagctatag gggctatggc tactatttct tccattgcaa tggtattttt
     9061 gatgcctatc tttggaataa atcaaggagc gcaacctatt ataggtttca attatggagc
     9121 tgaaaaatat gatagggtta aaaaagcata tttaggttca ttagtagtag ctactataat
     9181 tttatgtatg ggtatggtag tagttatgct tttcccagaa gctattatag gtatatttaa
     9241 taaagaccct gaacttatga atatatctgt taatggatta agaatatact tacttatgtt
     9301 gccaattgta ggcttatcag ttacaggaac aaactttata caatctatag gaaaagcaaa
     9361 aatggctatg ttattgagcc ttttaagaca agtaatttta ttgataccag cagtattaat
     9421 tcttcctaca ttcttaggtt tacagggtgt atggacagct caaccagtgt ctgattttat
     9481 agctacagta attacaggta tagttgtatt tagagaatta aaaagatata ctcctaaaac
     9541 tgaaaaatta aatgaaaatg aaagactaaa tgagataact actgagtaaa aatataaatt
     9601 cagataattg agcaagaaat tgcaaaaaat acgattatat gataaaataa aaccgctgtc
     9661 aaggataaga gaaattctaa ttatggagtg attttatgga atttacaaag aaaagcaaat
     9721 taaaaaatat gtatgtaaac atgaatgtag ctagaatgtt gtctaagata aatgagtata
     9781 agggtaggca actgctttac aaaaaacaac caaaagaaat tttagaaaac ctagaaaaaa
     9841 aatctttagt agattgttct gaatctacat acattggaaa tcaaagagat agtagtaatt
     9901 ttaatctaga aaagttgata agtaatgaag ttacacctag aagtagagag gaattgagta
     9961 ttgttgaata cagagatgtg gtaaaaacta ttaacagtgc ttatgagagt attcccatca
    10021 gttcacaaac gattcttgag cttcatgggt acttatataa attttcatct actagaggag
    10081 gaagttataa gtcagataat gattttattg aacacaattt aaaacctagc gaatttataa
    10141 gtattgattc aagtgtcaat aaagttgaaa aagctgtaga agaaatatgt gaagcttata
    10201 atacattgat agaggaagat gaaattgata tattaatatt aatttctgca tttgtgttag
    10261 atttcatatt gatacatcca ttcaaagaag gtaatataaa aatggcgaga gtacttatcc
    10321 tattgttact aaataaaaat gggtatgaag ttggaagata tataagttta ggaaagatat
    10381 ttgatgatag ttcatatgaa tattatagta atttaaatta tttgaaagcc tcaataggta
    10441 gtgaaaaagc agatatgaat gcatggattg agtatttttt agagacgata ttaactgcat
    10501 atgagaagct ggatgatagt ttaaatatat ctgataagaa aagacaaaca aaaactagta
    10561 gaatagaaaa aataataaat tctacccttg gatattttac aaaagaagat ataagagatt
    10621 tatgtcctga cattccagaa cctactataa atagagtttt taataatcta agaaaacaag
    10681 ataagataga agttgttgca agaggaagaa gtgcaaaatg gaagaaaaaa tattaaaaaa
    10741 tgtttaaata actaaaatgg tatagtgttt tacactatac catttttaat gtcattagca
    10801 tgagcaataa tttaacaact taagcaatat caattttatt tattgattat ttttgaactg
    10861 aaaaatgggg ttatatggta tactacaata ataattaatt ttggatgaga atatataacg
    10921 ttacagaata tcttaggagt atatgtataa aaaatataat aaaagtgtga ggtttagtaa
    10981 ttaacaaatt atgtggcttc acactttttt ataaaataaa aatacttagc agaagaatat
    11041 tttagttgat atgtttataa gatagtactt gtttgggtaa aagtataaat agtaaaaaag
    11101 tagaagtaat gtgtataaaa acataagtta cattctgtaa taatagttat tttataattc
    11161 aacaaaagaa tagaatgggt atatttgtga aataataata taaaataatc ttaggagtga
    11221 tcttatgaag aaaaaattat tatatataaa tgtaaattca aaacctgaag acttatcttc
    11281 aagtaaaact gtagcaagaa aatttataaa taaatttatg gaaaaaaaca aagattttga
    11341 ggttgaagag atagaccttt ataaagaaca tataccgaga cttgagtatc agtactttga
    11401 aaaaagaaat agcatagtta gtgaagaaaa tgctaaaaat ttagacgata aggatagaaa
    11461 agagcttaca aagattagaa atctttgtga ccaatttgtg agtgcaagtg tttatgtaat
    11521 agcagcacct atgtggagtt tatcttttcc agcaccactt aaagagtata tagattgtat
    11581 aattcaagat ggaaaaacta tatcttttga aggcaatgat aaaccacaag gaattttaaa
    11641 tgatattgat agaagtatgg tatatataca atcttctggt ggacacatac catgggtctt
    11701 gaagccagtt atgaataaag ggttaaatta tgtggaaagt attatgaaat ttataggaat
    11761 taaaaaattt gatgaattgt tagtagatgg aactggaact agtgaagaag aaagacaagc
    11821 tgcaatagaa aaagcatctg aaaaaataca tggtataata gatggtatga aattttaatt
    11881 ataatatttt attaaaaata taaaggaaaa acctctttta atgtagaaac ttatattgaa
    11941 ggaggcgaga atcatgcgag aagaaaaaag taatgaaaag tatgattgtt attggtgtaa
    12001 tcaagaaaat aatttctgtg tagaaataaa agataatata gtaatgatag atgatggcac
    12061 tggtacgtta aaacaagccg ttttcatagg gtataaacaa atccaaatta atttaaattg
    12121 ttcacattgt caaaacttaa atagaataaa attaaatttg tagaatttta aaatggaaat
    12181 tattgaagga attaaaaata gaaagtgtta atatttagac tgaaaattat attttataca
    12241 ataaaagttt atttaaataa cattgtattt taatatttat tttcagtctt actttattaa
    12301 aattattttt tggttatgtc tggaaaatat ctgtctacta atttttctga aatatttttt
    12361 aattggtcag ccattgaagt cagacttaat aaggctatca ataaatcatc tttattttct
    12421 ggatttatac taatattttc aaaattagac tctataaagt ccggtatatt ctttctttga
    12481 ttttctttta ttaacatgaa tttttcgtaa catgaaacta aatctttttc actgaaatta
    12541 tccttttcat acacaccatg taagattctt ttaatttctt gtattgtaag tgtatttttc
    12601 atagaataaa taattatcat ctgtaaaatt tgttctttag tatacttttt tcccttaact
    12661 ggtttgatta atccctcttt gctgtaatta tttatcatgg ttttagtaag aattttatca
    12721 ctttcaaatc ttttattagg agaaagttta ttgtcaatta gagaaataat ttgatccata
    12781 tataagtcaa tagagggaat atcgtttgaa gttatatctg cattatttag tgtttctagt
    12841 attatagtat taagttcatt attcatcata tgttacctcc ataatatata taatacacta
    12901 aattagaaag taaaacaata ttaagacttg taaaaaaaac ataaagtggt ataattaaat
    12961 atataatata gtaatgaaaa ctatatttat gaatctgatt tttaaaatac ataattgtag
    13021 gaggacgaaa tgtatcaatt ttttttaaag ggtagagacc caataagcag tttaactcat
    13081 tttataggtg cttgtttatc tcttttagca actataattt tagtttttca atctgttaca
    13141 ttacaggaaa cttctctctt gatgatagta tctgtatcgg tatttggact ttcactaatt
    13201 gctttatata gtgcaagttc gtattatcat tttttaaagg ggacaccaga acaagaattg
    13261 ttttttagaa aagtagacca tgcaatgatt tatgtattga ttgctggctc ttatacacca
    13321 atatgtctga attttatgga aaaaaaagaa ggcataatat ttgttacagc aatatggata
    13381 gttgcattta ttggcataat aataaaaata ttttggatgg atgcacctag atggttatct
    13441 accagtatat atttacttat ggggtgggca attgtttttg atataaatgc attcaattca
    13501 attcctaagg attgccttag actattaatt atggaaggtg tatcttactc tataggtgca
    13561 attatttata taattaaaaa gcctaatata agtcctgagt ttggatttca tgaaatattt
    13621 catattttta ttatgatagg ttctttattt cactttttag cagttttatt gtatgtttta
    13681 tagttttaaa agatttgatt aattgatact aaaattctac aatgaataaa atggaactgc
    13741 cttatataga ttatatcttc gacaataaga cagttcctta ttataaatat taaattctac
    13801 ttataataaa attttgataa aaatagtcca ttcaaaatgc ctattccata attcctttaa
    13861 tgtacttttc atttacgaca tatagtttga atttatgtac tataattata tcctctaaat
    13921 tctctgaaac actaacaatt ctgacacatt tgtttctaat ttctacaggt aaatctaaat
    13981 catttgttaa attcacatag tcatcatatt tatacataaa atcatccctt tacattaaga
    14041 tatac
//
LOCUS       DAMJYN010000092        13767 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.096, whole genome shotgun sequence.
ACCESSION   DAMJYN010000092 DAMJYN010000000
VERSION     DAMJYN010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13767)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13767)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13767
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.096"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            587..2017
                     /locus_tag="PC466_003052"
     CDS             587..2017
                     /locus_tag="PC466_003052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2770414.1"
                     /translation="MSSQESKPKGNLISNFRDDMRDPKKRAIYTYSSSINLAYNFIGY
                     FVSTVTNIFLTDVAKLGVIMAGGMQIIQSFIKIAVAPITGTVFDKQPFKKGKYYPWLR
                     YAPAALALTYGIFFIVPLMKISPALLLPLMTALLLIASCAQQVVFTIIYAIYPVVAKT
                     PRDRVIGSTTTNIFKEVGKFLVGFSYPLLLVLFADVLGGEGMGYLGTYLFFAAGCLLV
                     FWFSSTEIIKSGAEEEVLQKEEKPKIKASEMAKALFTNVPLMMAFCLEFLICIRSIGL
                     GPLAPYYFKYVIEDERGLAVFLSIMPLVSVAFMFFAPVFIKICREQKLASIISFSICA
                     LCHLLVAWTPWGKTTLGVTMLLAIGGGFSNVVSIINLNFFAGSCDYGHWKSGKDLPGL
                     SMSLYPVAIQVGVLLATTIRTVLMNSMGYQADMVVTEAVKSGFINMISYSMAIPLIIA
                     VVIAILYPVSDKKLNQIREELNQRNA"
     gene            2120..3223
                     /locus_tag="PC466_003053"
     CDS             2120..3223
                     /locus_tag="PC466_003053"
                     /EC_number="2.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate transaminase"
                     /protein_id="HDF2770415.1"
                     /translation="MIEKLLRNTVKELHQYVPGEPIEKVKEKYGVKEIIKLASNENPL
                     GPSPKAIEAMIEMLKQGQLYPEPEANELRRKLAEKLDLKPENFIVANGADNVITLIGE
                     AFINRGDEVIYCNPTFPSYRTATIKNEGIPVEVPLTEDYKYDLQGILDKITDKTKLIC
                     VCNPNNPTGTIVDDKELEEFLKKVPENIITILDEAYIEFLTVPNYVDGLKYVRENYNV
                     IVTRTFSKIYGLAGLRVGYGIAKDEIIRTLFTVKEPFSANRVAISGATAALDDEEFIK
                     ETYELNRVGMTYFKEEFTKMGFDVVDSQSNFLYVDMKTDIPKLFEDLKKRGFVIRPSA
                     THARVSIGTMEENKKFVAVLKEILNIKGEPSIG"
     gene            3238..3474
                     /locus_tag="PC466_003054"
     CDS             3238..3474
                     /locus_tag="PC466_003054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDF2770416.1"
                     /translation="MKRGVDMNLKINAERCKSCEYCVISCKKGALKISSKINKEGYAH
                     VEVDESKCILCGICYQVCPDNVFEIIKEKACQEA"
     gene            3491..4540
                     /gene="vorB"
                     /locus_tag="PC466_003055"
     CDS             3491..4540
                     /gene="vorB"
                     /locus_tag="PC466_003055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate dehydrogenase subunit
                     VorB"
                     /protein_id="HDF2770417.1"
                     /translation="MKKMWKGNHAIAEAALRGGCEFYAGYPITPQTEVMEFLSHRMSE
                     LGRTFIQSENEMAAIYMVYGAYASGMRSMTSSSGPGISLKQEGISYLCANHYPCVIVN
                     VQRWGPGLGSLDSAQTDYLRDTRGGGNGDYHLIVYAPNSIQETVDLMYNSFDVAEKYR
                     VPVEILTEAALGQMMEPVEFPEFKKREGDLGWTYDGSNRDHAKVADNQKPTFCMEKRM
                     RITENEQQWEDYQVEDAEYVFVAFGIPSRTTMNAVRRLREQGEKVGIIRPITVWPFPY
                     KAFEKVSKDVKGFISVESTDTGQLVEDVALASKKVCKENVPVYGLFSGNHIPKTLQVM
                     DTYSKIKSGEIKEVF"
     gene            4542..5282
                     /locus_tag="PC466_003056"
     CDS             4542..5282
                     /locus_tag="PC466_003056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate oxidoreductase"
                     /protein_id="HDF2770418.1"
                     /translation="MATEKLTPSVVSIPNKFCPGCGHGIVNRIIAEVIEEHGYEKNHV
                     LTLGVGCVCNMNFSWNGDKMQTAHGRASSTAIGVKVALPDTLVMTYQGDGDAYVIGLS
                     ETLNTAYRNHNVTVFVINNNNFAMTGGQMSWTTMPGQVTTTSVNGRDIKTTGSPLKVP
                     EMVANFFDVAYVARGSVHSPKEIINLKKYIKNAIEAQLNGEGYSLVEILAPCPTNWGV
                     SLEKSIKWMEEEIVPYYALGEFKQRDGE"
     gene            5285..5824
                     /locus_tag="PC466_003057"
     CDS             5285..5824
                     /locus_tag="PC466_003057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase family
                     protein"
                     /protein_id="HDF2770419.1"
                     /translation="MEKELVFAGFGGQGVLTLGLIVAESALELGKQVTWMPAYGPTMR
                     GGKAYSVVKFSDESIGGPDMEEIDVLVAMNKPSLDYINLVKEGGTVVINTSAIDENVT
                     LREDISVVKINCQELAQKVNNPKAANIVVLGALIAKTGLLEKELALKTMCDFFEEKGK
                     GKFNVQNEAAFMEGYNNAI"
     gene            5948..8047
                     /locus_tag="PC466_003058"
     CDS             5948..8047
                     /locus_tag="PC466_003058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate--CoA ligase family protein"
                     /protein_id="HDF2770420.1"
                     /translation="MSLEKLIRPKSIAIVGVTDKLGFGRSAALSIVKSKETDRVYYVN
                     PKREELFGRKCYKMIQEVPEVVDCVVVCTPRNVVPSVLKDSGELGTKAAVVYASGFAE
                     EGTEEGTDLENQLIEISNTYDMKILGPNCMGLLNCIDKVNLWAGGSKWALDTKKPGIG
                     IVGQSGFITAEIVSSDYFNISYGFSTGNGNIVTLEDAVDFLVDDDYASVIAIYLEGLK
                     NPQKFIDALKRAAQKRKPVIILKSGRSEKGAISAASHTGNLAGSSKAFESIFEKYGVI
                     SVENLEQFMCLAQAFSVLDGNLPANSNFAAINFSGGENTICADLAEENGVELAEISSE
                     TKEEMKKYLPGFATPKNPLDATTALFHEKDMIVGLLHTFEKDDSVGFTMVGANIRDEE
                     NEMHETLCKAVSEAREQGLKKPVFAVPTLEGNRYLDYRTRLEDNQVPIMSSVGTTFTC
                     FNKMAKFIDYDYSKRTLEFKAVKKRESNNVVALSELDSKIEMKKYGVPVPGQGNTKSI
                     DELDEILKYIKYPVVLKINSSEILHKSDVGGVKIGIKNRDEAVDAYNEILTNVKKAKP
                     DANIDGILVQEMVESGIEIIIGITNDDQFGPMLLVGLGGVFVEVFKDTTLYPLPINHD
                     EAIMMLKKLKSFKLLNGYRGSEPCDIDALADMMVKLGKYAYENKDEVKEIDLNPVFVY
                     PKGKGVCAVDALIVKYK"
     gene            complement(8314..8829)
                     /locus_tag="PC466_003059"
     CDS             complement(8314..8829)
                     /locus_tag="PC466_003059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferritin"
                     /protein_id="HDF2770421.1"
                     /translation="MISAKMEKLLNEQINHELYSAYLYLSMSSYLEAEGLKGFSNWFY
                     VQYKEETDHAMFFYKYLHNVGGKVQLDAIPMPDSDFTSAMDILERTLAHEKKVTALIN
                     NLAAVANSESDFRTSQFLLWFISEQAEEETNCEDNIKRVKLAGEGGLFFVDQEFANRT
                     YAAPTNPPVTI"
     gene            complement(8921..10132)
                     /locus_tag="PC466_003060"
     CDS             complement(8921..10132)
                     /locus_tag="PC466_003060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HDF2770422.1"
                     /translation="MSNKQGSNIKDVKIKNKLIILKLLSTNTPMSRVDLAKSTGLTKM
                     TLSNLVTELINENMIREIESSTLNAHSSGRKPILLDISNISPCICGILIRRNICKVII
                     SDLKGNIVKQLSETYPKCLSNDVLKDIIKRMFTKIMKINKRDIIGIGISSIGPVDDIN
                     GTILNPPDFGNVSNLNIVDFIKEMSDFPIFLINDANSGALAEKMYGLGKNISNYIYLH
                     IMNGIGAGLVLENKLHTGNLGQSGEIGHTSINFSGPLCSCGNNGCLDYYTSVSNLIKR
                     IESLSHIYPNSPLINCKDFSLVKLIDEANNKDSLAMFLLDEFCTYVSYALVNTLTLID
                     CSSIIIGYDFNIPGTFIENTLLKKLTASASFSKYKKISVRHSNFGANAPLIGSIAIVS
                     YNFFNGSINFY"
     gene            10808..12250
                     /locus_tag="PC466_003061"
     CDS             10808..12250
                     /locus_tag="PC466_003061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HDF2770423.1"
                     /translation="MRTIRRVLALGLTLAIFLINVPNVDALTSDTIKGNNIYETAGLI
                     ADKKSYDTAIMVNMDNSIADGLSASGLAGAVDAPILLAQKNKIPNETKQRLKNVKKIY
                     IIGKELSISKSVETELKNTGAQVTRLGGDDRIKTSYSVAKEVNGIKKVDEVILTNAYK
                     GEADTISAAPVSVRDIAPIVLTDGKSVPFSTSNVKTYAVGGSISMSTSLVNKTNAKRL
                     GGSDRYDTNKKVIKEFYPDASEFYLSDGYDLVNALTGSTIAKENPIVLVSESSDKSIL
                     AGADKITRLGSISDSVYNKCVSAAQNNGDSSTKGESPMKNETSILGQPTASLEACLKW
                     AKSKKANDLFIELIPILYDTAVQEGVNPVLAVAQSAKETGFCNFGGVLDASFKNPCGL
                     KTSVGGSDTDKNAHSRFDTWEEGILAQIQHLCLYAGQDGYPLSNPVDPRHEKSLFGKA
                     KTVESLSNNWAGGQYGQDLVRMMGEIEATK"
     gene            12292..12645
                     /locus_tag="PC466_003062"
     CDS             12292..12645
                     /locus_tag="PC466_003062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770424.1"
                     /translation="MKKSNIFSIIFPTIIMVLMFLTFATDIFNIPDIQSKSIFVVGMV
                     LIFPISFLIQGIICVLNKTNWILSLIVSLVTYIVLMYIFLNDSAYIYVLLYTAFYMIG
                     HITAKLYYKIKTFKN"
     gene            12836..13657
                     /locus_tag="PC466_003063"
     CDS             12836..13657
                     /locus_tag="PC466_003063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase HisJ family protein"
                     /protein_id="HDF2770425.1"
                     /translation="MNLIDNHIHTNFSSDGKDSMEDTIKKAISIGVRYLTFTDHLEHD
                     EDRGFCINYNDYVPVFNKFKEKYKKDIELLLGVEVGYRKHLKNEIEEIINSNPFDFVL
                     CSTHTIDNVPVPSKAYFKGLSKEDAYYKYFNSILETNREFGDYNIYGHLDYISRYGIY
                     SDNRVIYNDFKDVIDEVLKSIINNGSGIELNTSGYRYGLNAIHPNEDILKRYKELGGF
                     IVTVGSDSHRVEDICKDFDVAYDMLKYLDFKYVSLFKERETYFVNIKKVKSNNIA"
BASE COUNT         5260 a         1599 c         2456 g         4452 t
ORIGIN      
        1 tagtacgata tttgttttat tggttttaga ttaatatagc tataataatt tatgatatta
       61 gatggaaatt acgtaaaaat agaaaattga aaattctgaa atttttgcat attgatattt
      121 atctcataga ttcttttttg taattgtaac acgcttttat ttttaaatca atagtacatg
      181 tataaaaata aaaggaatct aaataagaaa aagatatttt taatatctgg atgtagtata
      241 gaaatatctt gaataaatta ttcttgaata aaattataaa aatttaaaat cactagaaat
      301 atgataaaat aatttaaaat acgcatttca atgacatttc aagacaagaa aataataaaa
      361 aacaaatcta aattaagcct aaatagcttt ttagttaatt ttagtagtaa aaaataaaac
      421 ttaaaaagtg tttgacaatt atgaatttta agaatataat taaattaaaa ttatacacat
      481 ataaaaatat actcctgaat caagaatgag atatttaaga ttcaaaatat atattattat
      541 acgtgaataa tgaaaagtaa gaaaatttta taagggaggg gtagatgtga gtagtcaaga
      601 aagcaaacca aaaggaaatc ttatatcaaa ttttagagat gatatgagag accctaagaa
      661 aagagcaata tacacatatt caagttctat aaacttagcg tacaatttta taggttactt
      721 tgtatcaact gttacaaata tttttttaac tgatgtggca aaacttggtg taattatggc
      781 aggtggtatg caaattatac aatctttcat aaaaattgct gtagctccta taacaggtac
      841 agtatttgac aaacaaccat tcaaaaaagg aaagtattat ccatggctta gatatgcacc
      901 agcagcgtta gcattaacat atggaatatt tttcatagtt ccattaatga aaataagtcc
      961 agcattactt ttacctttga tgacagcttt attattaata gcatcttgtg ctcagcaagt
     1021 agttttcact ataatttatg ctatttaccc tgtagttgct aagacaccta gagaccgagt
     1081 tataggctca actactacta atatatttaa agaagttggt aaattcttag taggtttttc
     1141 atatccgtta ttattagttt tatttgcaga tgtattaggt ggagaaggaa tgggttattt
     1201 aggtacctac ttattctttg cagcaggatg ccttttagta ttttggtttt cttcaacaga
     1261 gataataaaa tctggagcag aagaagaagt tcttcaaaaa gaagagaagc caaagattaa
     1321 agcaagtgaa atggcaaaag ctctattcac taatgtacca cttatgatgg cattttgttt
     1381 agaatttctt atatgtataa gatctatagg attaggacct ttggctccat attattttaa
     1441 atatgtaata gaagatgaac gtggattagc agtattttta tcaatcatgc ctttggtaag
     1501 tgtagcattc atgtttttcg caccagtgtt tataaaaatc tgtagagagc aaaaactagc
     1561 ttcaataatt tctttttcta tatgtgcact atgccactta ttggttgcat ggactccttg
     1621 ggggaaaact actttaggag taactatgtt gctggcaatt ggtggaggtt tttcaaatgt
     1681 agtatcaata ataaatctta atttctttgc cggttcttgt gattatgggc attggaaatc
     1741 aggaaaagac ttacctggct taagtatgtc actatatcca gttgcaatac aagtaggagt
     1801 attacttgca actactataa gaacagtttt aatgaactca atgggatatc aagctgatat
     1861 ggtagtcaca gaagcagtta aatcaggttt tataaatatg atttcttatt ctatggcaat
     1921 acctttaata atagctgttg ttatagcaat actatatcca gtaagtgaca agaaattaaa
     1981 ccaaataaga gaagagttaa atcaaagaaa tgcttagtta aaagaaagtt aagtagatgg
     2041 ttaatttaag ctattaaagt aagtagacgc aatagcgttt atataaatca aaatacatat
     2101 acagaggggg cttttaaaaa tgatagaaaa attattgaga aataccgtaa aagaattaca
     2161 tcaatatgtt ccaggtgaac caatagaaaa agttaaggaa aaatatggtg taaaagaaat
     2221 aataaaatta gcttcaaatg aaaatcctct aggaccatca ccaaaagcaa tagaagctat
     2281 gattgaaatg ctaaaacaag gtcaacttta tccagagcca gaagctaacg aacttagaag
     2341 aaaattagct gaaaagctag atttaaaacc agaaaatttt attgttgcta atggtgcgga
     2401 taacgttatc actctaatag gtgaggcttt tataaataga ggagatgaag ttatatattg
     2461 taacccaaca tttccatcat atagaactgc aactataaaa aatgaaggga taccagtaga
     2521 agtgccttta acagaagatt ataagtatga tttacaaggt atattagata agattacaga
     2581 taaaacaaaa ttaatatgtg tatgtaaccc taataatcca acaggaacaa ttgtggatga
     2641 taaagagtta gaagaatttt taaagaaagt ccctgaaaat attataacta tattggatga
     2701 agcatatata gaatttttaa cagttcctaa ttatgtggat ggacttaagt atgtaaggga
     2761 aaattataac gttatagtaa caagaacttt ctctaaaata tatggtcttg cagggcttag
     2821 agtaggatat ggtattgcta aagatgagat aataagaact ttatttacag taaaagagcc
     2881 tttctctgca aatcgtgttg ctataagtgg agcaacagca gcacttgatg atgaagagtt
     2941 tataaaagaa acatatgaat taaatagagt tggaatgact tactttaaag aagagtttac
     3001 aaaaatgggg tttgatgttg tagattcaca atcaaatttc ctttatgtag atatgaaaac
     3061 agatatacct aagttatttg aagacttgaa aaaaagaggg tttgtaataa gaccaagtgc
     3121 tacacatgca cgtgtaagta ttggaactat ggaagaaaat aagaaatttg tagcagtttt
     3181 aaaggaaata ttaaatatta aaggagagcc aagtattgga taatagatag aaatattatg
     3241 aaacggggtg tagatatgaa cttaaaaata aacgcagaga gatgtaaaag ttgtgaatac
     3301 tgcgttatat cttgtaaaaa aggagcatta aaaatatcaa gtaagataaa taaagaaggt
     3361 tatgctcatg tagaagttga tgagagtaaa tgcatacttt gtggaatttg ctatcaggtg
     3421 tgtccagata atgtttttga aataattaaa gaaaaagcat gtcaagaggc ttagaaggag
     3481 ttgggataat atgaaaaaga tgtggaaggg gaaccacgcc attgcagaag cagccctaag
     3541 aggaggttgt gaattttatg caggatatcc aattacacca caaacagagg taatggaatt
     3601 tttatcacat agaatgtctg aacttggaag aacttttata cagtccgaaa atgagatggc
     3661 tgctatatat atggtatatg gagcatatgc aagtggaatg aggtctatga cgagttcttc
     3721 aggaccagga atatctttaa aacaagaagg gatttcttac ttatgtgcaa atcattaccc
     3781 ttgtgtaatc gtaaatgtac agagatgggg gcctggtctt ggctcattgg actcagcaca
     3841 gacagactat ctaagagata ctagaggggg aggaaatgga gattatcatt tgatagttta
     3901 tgcaccaaac agtattcaag agactgtaga tttgatgtat aactcatttg atgtagcgga
     3961 aaaatacaga gtgcctgtcg aaattttgac agaagcagct ttaggtcaaa tgatggaacc
     4021 agtagaattt ccagaattta agaagagaga aggagattta ggttggactt atgatggaag
     4081 taatagagac catgcaaagg ttgcagataa ccaaaagcca actttttgta tggagaaacg
     4141 tatgagaata actgaaaatg aacaacaatg ggaagattat caagtagaag atgcagaata
     4201 tgtgtttgta gcgttcggta taccatcaag aacaactatg aatgctgtta gaagacttag
     4261 agaacaaggt gaaaaagttg gaataataag accaataaca gtatggcctt tcccatataa
     4321 agcatttgaa aaggtaagta aagatgtaaa aggatttatc tcagtagaat caacagacac
     4381 aggtcaatta gtagaagatg ttgctttagc ctcaaagaaa gtatgtaaag aaaatgtacc
     4441 tgtgtatggt ttatttagtg gaaatcatat accaaaaaca ttgcaagtaa tggacactta
     4501 tagcaaaata aaatctggcg aaatcaagga ggtgttctaa tatggctaca gaaaaattaa
     4561 cacctagcgt tgtttcaata ccaaacaagt tttgcccagg ttgtggtcat ggaatagtaa
     4621 atcgtataat agcagaggta atagaagaac atggatatga aaaaaatcat gtattaacat
     4681 taggagttgg ttgtgtctgc aatatgaatt ttagctggaa tggtgataag atgcaaactg
     4741 cacatggtag agcttcatct acagctatag gagttaaagt agcacttcca gatacattag
     4801 taatgactta ccaaggtgat ggagatgctt atgttatagg tctttctgaa actttaaata
     4861 cagcatatag aaatcataat gtgactgtat ttgtaataaa caataataat tttgcaatga
     4921 ctggtggaca aatgtcatgg accactatgc cgggtcaagt cacaacaaca agtgtaaatg
     4981 gaagagatat aaagactact ggtagtccac tgaaagttcc tgagatggtg gcaaacttct
     5041 ttgatgtagc atatgtagca agaggttcag ttcatagccc aaaggaaata attaatctaa
     5101 aaaaatatat aaaaaatgca atagaagctc aattaaatgg agagggatat tccttagttg
     5161 aaatattagc accttgccca actaactggg gtgtatcact agagaaatct atcaaatgga
     5221 tggaagaaga aatagtgcca tattatgctc ttggcgaatt taagcaaagg gatggtgaat
     5281 agttatggaa aaagagctag tatttgcagg gtttggtggt caaggagttt taactcttgg
     5341 tctgattgta gctgagtcag cacttgaatt ggggaaacaa gtaacttgga tgcctgcata
     5401 tggtccaact atgagaggtg gaaaagccta tagtgtagta aagttttctg atgagagtat
     5461 aggtgggcct gatatggaag aaatagatgt tttagtagca atgaataaac catctttaga
     5521 ttatataaat ttagttaaag aaggtggaac agtagttatt aatacatctg caatagatga
     5581 gaatgtaaca ttaagagaag atataagtgt agttaaaata aattgtcagg aattagctca
     5641 aaaagtaaac aatccaaaag cagcaaatat agtagtactt ggagcattaa ttgctaaaac
     5701 tgggttactt gaaaaagaat tagctttaaa aactatgtgt gatttctttg aggaaaaagg
     5761 aaaaggaaag tttaatgttc aaaatgaagc agcattcatg gaaggctata ataacgccat
     5821 ttgataaatt acccttatct taagtgattt atctcaagat ttaataatct ttagtgccaa
     5881 gagaaacttc atcttgagat aaaattcact taaaatcaca actataaaca tataggagcg
     5941 tgaatttatg agtttggaaa aacttattag accaaaaagt attgctatag taggagtgac
     6001 tgataaactt ggttttggaa gaagtgcagc acttagtata gtaaaaagta aggaaacaga
     6061 tagagtatat tatgttaatc ccaaaagaga agaattgttt gggagaaaat gttataagat
     6121 gatacaagaa gttccagaag tagtagactg tgtagtagta tgtacgccta gaaatgtagt
     6181 tccatctgta ttaaaagatt ctggagagtt aggaacaaag gcagcagtgg tatatgctag
     6241 tggatttgca gaggaaggta cagaggaagg tacagattta gaaaatcaac ttatagaaat
     6301 atcaaataca tacgatatga aaatattggg tccaaactgc atggggttgc taaattgtat
     6361 agataaggtt aatctatggg caggaggttc taaatgggct ttagatacta aaaaacctgg
     6421 tataggaatt gtaggtcaaa gtggatttat aactgctgaa attgtttcaa gtgattattt
     6481 taatatatct tatggttttt caacaggaaa tggaaatata gttacactag aagatgcagt
     6541 agatttcctt gtagatgatg attatgcatc agtaatagca atttaccttg aaggtttaaa
     6601 aaatcctcaa aaatttatag atgctttaaa aagggcagca caaaaaagaa agccagtaat
     6661 aatattgaaa tcaggaaggt cagaaaaagg tgctatttct gctgcctctc atacaggaaa
     6721 tttagctggt tcgagtaaag cttttgaaag tatttttgaa aaatatggag taatttctgt
     6781 ggaaaattta gaacagttta tgtgtttagc acaagctttt agtgttttag atggtaattt
     6841 acctgcaaat tctaattttg cagcaataaa cttctcagga ggagaaaata ctatttgtgc
     6901 agatttagca gaagaaaatg gtgtagaact tgcagaaata tcttctgaaa ctaaagaaga
     6961 aatgaaaaaa tatcttccag gatttgcaac acctaaaaat ccactagatg ctacaacagc
     7021 attattccat gaaaaggata tgatagtagg tttattacat acctttgaaa aggatgatag
     7081 tgttggattt actatggtag gtgcaaatat aagagatgaa gaaaatgaaa tgcatgaaac
     7141 cctttgtaaa gctgtaagtg aagctagaga acaaggattg aaaaaacctg tgtttgcagt
     7201 tcctacactt gaaggaaata gatatttaga ttataggact agattagaag ataatcaagt
     7261 gcctataatg tcatcagttg gaactacatt tacttgtttt aataaaatgg ctaagtttat
     7321 agattatgat tattcaaaaa gaactttaga atttaaagct gttaagaaaa gagagtcaaa
     7381 taatgtagta gcattatcag aattagatag taagattgag atgaaaaaat atggagtacc
     7441 agttccagga caaggtaata caaaaagtat tgatgaatta gatgaaatct taaaatatat
     7501 taagtatcct gttgttttaa aaataaattc ttctgaaata ttgcacaaat ctgatgttgg
     7561 aggagttaaa ataggaatta agaatagaga tgaggcagta gatgcatata atgagatttt
     7621 aactaatgta aaaaaagcaa aaccagatgc taatattgat ggtatattag ttcaagaaat
     7681 ggtagaaagt ggtatagaaa ttattattgg tataactaat gatgaccaat ttggaccaat
     7741 gttattagtc ggtttaggag gagtatttgt agaggtattt aaagatacta cattatatcc
     7801 attacctata aatcatgatg aagctattat gatgcttaaa aaactaaaat catttaagct
     7861 tttaaatggc tatagaggaa gtgagccttg tgatattgat gctcttgcag atatgatggt
     7921 caaattagga aaatatgctt atgaaaataa ggatgaagtc aaggaaatag acttaaatcc
     7981 agtgtttgta tatcctaaag gaaaaggcgt atgtgcagta gatgccttaa tagttaaata
     8041 taaatagttt ataagttttg gtattcaacc ataattaaag caccgactga aaatcacatt
     8101 ttgtaagtta gatagtgtga ttttcagtca ccccaaattt aatttaaaaa tattttaaaa
     8161 tgaaagtata gttttgagtt taattgtgaa atagcactgt ataaacaata aaatactacg
     8221 tataaaacga ataataaaag gtgttttaat gataagaatc aatcttgatt ttcattaaaa
     8281 caccttcttt attatattaa aaatttttaa acgttatatt gtcacaggtg ggtttgttgg
     8341 agctgcatat gtacgattag caaattcttg gtcaacaaag aatagaccac cctctccagc
     8401 aagtttaaca cgttttatat tgtcttcaca atttgtttct tcttctgctt gttcagatat
     8461 aaaccaaagt aagaattgag aagttctaaa gtctgattca gagtttgcta cagctgctaa
     8521 gttgtttatt aaagctgtaa cctttttttc atgagctaac gtacgctcaa gaatatccat
     8581 tgcagaagta aagtctgaat ctggcattgg gatagcatca agctgaacct ttcctcctac
     8641 attatgtaag tatttgtaaa aaaacatagc gtggtctgtc tcttctttat attgaacata
     8701 aaaccaatta gaaaatcctt taagtccttc tgcttcaagg taagaagaca tagaaagata
     8761 aagatacgca gaatataatt catggttaat ctgctcatta agtaattttt ccattttagc
     8821 tgaaatcatt tttatacctc caaattttaa atgctcttat aaaatataat aatattaaat
     8881 ggaaaaatat tcaataaaag tgtttaaata ttttacatat ttaataaaaa tttatactac
     8941 cattaaaaaa attataactt acaatggcta tagagccaat taatggtgca tttgctccaa
     9001 aatttgaatg ccttacactt atttttttat atttagaaaa acttgctgaa gcagtcaatt
     9061 tttttaataa tgtattttct ataaatgtac caggtatatt aaagtcatag cctattatta
     9121 tagaactaca atcaatcaat gtaagtgtat taactaatgc atatgatacg tatgtacaaa
     9181 attcatcaag caaaaacatg gcaagactat ctttattatt tgcctcatct attaacttga
     9241 ctaaagaaaa atctttacag ttaattaatg gggagttagg ataaatatgg ctcaatgatt
     9301 caattctttt aattagatta ctgacacttg tataataatc taaacatcca ttgttaccac
     9361 aactgcacaa tggtccacta aaattaattg atgtatgtcc tatttctcca ctttgtccta
     9421 ggttgccagt atgaagttta ttttctagaa ctagaccagc tccaatacca ttcattatgt
     9481 gtaggtatat ataatttgat atatttttac ctaaaccata cattttttct gctaatgcac
     9541 ccgaattagc atcatttatc aaaaatattg gaaaatcaga catttctttt ataaaatcta
     9601 ctatatttag gtttgataca tttccaaagt ctgggggatt tagtatggta ccatttatat
     9661 catctactgg acctattgaa gaaataccaa ttccaattat atctctcttg ttgattttca
     9721 ttattttagt aaacattctt tttattatat cttttaaaac atcatttgat agacatttag
     9781 ggtaagtttc agaaagttgt tttacaatat taccttttaa atctgaaata attaccttac
     9841 atatatttct tcttattagg attccacaaa tacaaggcga tatattagaa atatctaata
     9901 aaataggttt acgacctgat gaatgtgcat ttaaagttga tgactctatt tccctaatca
     9961 tattttcatt aataagttca gtaactagat ttgataaagt cattttagta agtcctgtag
    10021 acttagctaa atcaactctg gacataggtg tatttgtaga aagtaatttc aatattatta
    10081 acttattttt aatttttaca tctttgatgt tagaaccttg tttgttactc atcataaatc
    10141 tccttaaata aagttaagtg ttttatttat tttcaagtat actatcacct tataatagag
    10201 taacattttt ttacttgaaa atatcattaa ttagaatata tcacattata tatcataaaa
    10261 catataaaaa aatgttagaa ttaaattaaa agtgaaaagt agattgatat ataaatagta
    10321 aatacttaat taaaaaaaga taatgatagc aataattatt gttaccaaga atctactact
    10381 tcaagtgtta ccttaggtat ttaagttgat agtggtttgc acgtaataaa cttgatgtaa
    10441 tatatattct taataatatc gataaaagat ttacttaaaa ataatataga ttatgtaaac
    10501 atataatcta tttattgtat acaataaaat ttcattttgt aaaacagtga attaaatatg
    10561 taatatagat atcgattttt attacaaatt gttactaaat ataggtacat tagaacaaaa
    10621 atctagtaaa ttgtaactaa aatgtaaatt tttcctttaa tctatacaat attatggaaa
    10681 ctttttgtaa tttatgatat aataacaaat atataattat taaattataa taaatgacta
    10741 tagcgtagat gtaatactat gttatagtca tttttgaatt aaacttgata tatcaagggg
    10801 gaagaatatg agaacaatta gaagagtttt agcattaggt ttaacattag ctatatttct
    10861 aataaatgta cctaatgtag atgcattaac atcagataca attaaaggta acaatatata
    10921 tgagacggct ggattaatag cagataaaaa gagttatgat acagcaatta tggtaaatat
    10981 ggataattct atagcagatg gtctttcagc aagtggtctt gcaggtgctg ttgatgctcc
    11041 aattttgctt gcacaaaaaa ataagatacc aaatgaaaca aaacaaagat taaaaaatgt
    11101 taaaaagata tacataatag gtaaagaatt atcaataagt aagtcagtag aaactgaact
    11161 aaaaaacaca ggggcacagg taactagatt gggtggagat gacagaataa agactagtta
    11221 tagtgttgct aaagaggtaa atggtatcaa aaaagttgat gaagtgatat taactaatgc
    11281 atataaagga gaagcagata caataagtgc tgcacccgta tcagtaagag atatagctcc
    11341 tatagtactt acagatggaa agagtgtgcc tttttcaaca agcaatgtaa aaacatatgc
    11401 agtaggtggg agtatatcaa tgagcactag tttagttaat aaaactaatg ctaaaagact
    11461 tggtggttca gatagatatg atacaaataa gaaagttata aaagagtttt atccagatgc
    11521 atcagaattt tatttgagtg atggatatga tttagtaaat gcacttacag gttctacaat
    11581 tgctaaggaa aatccaattg tattggtgtc agaaagtagt gataagtcta tattagcagg
    11641 agcagataag attactagat taggttcaat aagtgacagt gtgtataata agtgtgtttc
    11701 tgctgcacaa aataatggcg attcgtctac aaaaggtgag tcacctatga aaaatgagac
    11761 aagcatatta ggtcagccaa cagctagttt agaagcgtgc ttaaaatggg caaaatctaa
    11821 aaaagctaat gatttattta tagagttaat accaatatta tatgatactg ctgttcagga
    11881 aggtgttaat cctgttttgg cagtagctca atctgcaaaa gaaactggtt tttgtaattt
    11941 tggtggagta ttagatgcat catttaagaa tccttgtgga cttaaaactt ctgtaggtgg
    12001 ttctgatact gataagaatg cccattcaag atttgatact tgggaagaag gaatattagc
    12061 tcaaattcaa catttatgct tatatgcagg acaagatggt tacccacttt caaatccagt
    12121 agaccctaga catgaaaaat ctttatttgg taaggctaaa acagttgaaa gtttatctaa
    12181 taattgggct ggaggtcaat atggacaaga tttagtaaga atgatgggag aaattgaggc
    12241 aacaaaataa ttgaagatta tcaaatatcc aataaataag gattgattat tatgaaaaag
    12301 agtaatattt ttagtatcat atttcctaca atcataatgg tgctaatgtt tttaactttt
    12361 gctacagata tatttaatat tccagatatt caatctaaaa gtatttttgt tgtgggaatg
    12421 gttttgattt ttccaatttc ttttttaata caagggataa tttgtgtatt aaataagact
    12481 aattggattt tatctcttat tgtgtcttta gtaacttata tagtattaat gtatatattt
    12541 ttaaatgatt ctgcatatat atatgtttta ctttatacag ctttttatat gattggacat
    12601 ataacagcta aactctatta caaaattaag acttttaaaa attaaattga agtatataaa
    12661 agtaacatta agagaagtat ccttaatgat tttctaaaat cagaaatagg tgcttctctt
    12721 ttttgtaaaa ataaaagtat gtaaataaaa tttaaccatt ataattttct tttaacaaat
    12781 gtatacaata aacttgttgt ataattaaga tagataaaat aaagggaggg ataatatgaa
    12841 tttaatagat aatcatattc atactaattt ttcaagtgat ggaaaggatt ccatggaaga
    12901 tacaataaaa aaagctataa gtattggtgt tagatatttg acttttacag accatttaga
    12961 acatgatgaa gatagaggat tttgcataaa ttataatgac tatgttccag tatttaataa
    13021 gtttaaagaa aaatataaaa aggatataga gttattacta ggtgttgaag taggttacag
    13081 aaaacatcta aaaaatgaaa tagaagaaat aataaattct aatccttttg attttgtatt
    13141 gtgctcaact catacaattg acaatgtacc tgttccatca aaggcgtatt ttaaaggtct
    13201 tagcaaagaa gatgcgtatt ataaatattt taatagcata cttgaaacta atcgtgaatt
    13261 tggagattac aatatatatg gtcatttgga ttatatatct aggtatggaa tatattcaga
    13321 taatagagtt atatacaatg actttaaaga tgttattgat gaggtcttaa agtcaataat
    13381 caataatggg agtggtatag agctaaatac ttctggttat agatatggat taaatgctat
    13441 acatccaaat gaagatattc taaaaagata taaagaactt ggaggattta tagttactgt
    13501 aggttctgat tctcataggg tagaagatat atgtaaagat tttgatgtgg cctatgatat
    13561 gcttaagtat cttgacttta aatatgtatc tttatttaaa gaaagagaaa cttattttgt
    13621 aaatataaaa aaagttaaat ctaacaatat agcttagagt atgttttgaa gtaaattaat
    13681 ggatagttaa aaagttaata gttataatat tgtatcctct agaaaaatac tagaggtttt
    13741 tattttgcta aaataactaa atagaat
//
LOCUS       DAMJYN010000093        13245 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.097, whole genome shotgun sequence.
ACCESSION   DAMJYN010000093 DAMJYN010000000
VERSION     DAMJYN010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13245)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13245)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13245
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.097"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(215..679)
                     /locus_tag="PC466_003064"
     CDS             complement(215..679)
                     /locus_tag="PC466_003064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4624 family lipoprotein"
                     /protein_id="HDF2770426.1"
                     /translation="MKKLVIILISIISVVSLTACKKSNESKYNNLNNKESGQTTIEMD
                     LDKNYDTSDPFVNARLFCVSNDIDVLDTEISFKMDGDSGIVEIKDNKTDETLWSNTWH
                     GSVDNDTFAISLSNIQKEKEYAICFTGIKINHAVVKVTFESNLVKEKEKPSK"
     gene            complement(1003..1611)
                     /locus_tag="PC466_003065"
     CDS             complement(1003..1611)
                     /locus_tag="PC466_003065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HDF2770427.1"
                     /translation="MKKTIIKNVNPMIENKFIGLFEIEYKNKLDEDKVWMVASRKSSE
                     QLKNIYLKNEEDSVDAVVIVGLHKSSKKLILIRQFRVPINGYIYELPAGLVDEGESID
                     ISVERELREETGLTLLEIKKNKSIDKVYLSPGMSDESVAFVYCICDGDITDEFLEPDE
                     EIEALLISQEDAKEILQSNHKIDTKAFLILQMFVSLGAKLFE"
     gene            complement(1693..2394)
                     /locus_tag="PC466_003066"
     CDS             complement(1693..2394)
                     /locus_tag="PC466_003066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770428.1"
                     /translation="MKFIVEKEVFDKLENVCFGVVVAKGIDNTKEIERISNLLDISID
                     RVEDYFKDKKVKESEEIIPYREAFRSLGMNPNKFMSSIEAMTTRVAKNKKLPHINPIV
                     DLGNSISLKYLLPMGAHDMDFRNDDVYVRFSKKGDKFVPFGETDVELMEEGELIYSVG
                     DMVKTRRWIWRQGEEGKITNSSKNIFFPIDGFTDANLDKVMSAREELAKLLKEIFNCE
                     IKVGFVDKDNPEMEI"
     gene            2621..2887
                     /locus_tag="PC466_003067"
     CDS             2621..2887
                     /locus_tag="PC466_003067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HDF2770429.1"
                     /translation="MKNFILIYFIVINSIAFFSMYIDKKRAIRNEWRIKEATLMSIAV
                     IGGSIGSMIGMYSFRHKTKHIKFTFGIPFILFLQFLLVYFYILK"
     gene            complement(2990..3409)
                     /locus_tag="PC466_003068"
     CDS             complement(2990..3409)
                     /locus_tag="PC466_003068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjdF family protein"
                     /protein_id="HDF2770430.1"
                     /translation="MDKISGKLTVLFEEPFWVGIFERQDGKKYEACRVVFGAEPKEVE
                     VYEFILERFFSLDFGSIKLEKNVTKDNIGYKRMQRKVKKEQEKETIGTKAQNALKLQY
                     EERKQDRKNLAKNRKEEEKERIFNLKQEKRKAKHKGH"
     gene            complement(3676..4458)
                     /locus_tag="PC466_003069"
                     /pseudo
     CDS             complement(3676..4458)
                     /locus_tag="PC466_003069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430254.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
     gene            complement(4523..5284)
                     /locus_tag="PC466_003070"
     CDS             complement(4523..5284)
                     /locus_tag="PC466_003070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896901.1"
                     /note="N-terminal region resembles flavodoxins. C-terminal
                     ferrodoxin region binds two 4Fe-4S clusters; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EFR1 family ferrodoxin"
                     /protein_id="HDF2770431.1"
                     /translation="MIGIYFSGTGNSRYCVEKFLQEYDITANSYSIEDNELLQHINNH
                     ENIIFSYPVQYSNVPKILKDFIINHSTLWNGKRVFIIATMALFSGDGSGVLARILKKY
                     GAITVGGLHVKMPDSIGDEKVLKHSLEYNKKLVIKAEKKVTKAAKKLKHGSPPKEGLG
                     FLSHIVGLFGQRLYFINKTNMYTDKLKINTEECIVCGKCVNLCPMKNLVIKNCMIVAN
                     GQCTMCYRCVNNCAKKAITLLGKKVVEQSNIKKYM"
     gene            complement(6333..7145)
                     /locus_tag="PC466_003071"
     CDS             complement(6333..7145)
                     /locus_tag="PC466_003071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDF2770432.1"
                     /translation="MYLERPELYKQSEINFWDDEYISKQLLKAHLDTNFEGASRNFNF
                     IEDSVNWIVTVANPVNYPNLLDLGCGPGLYAEKFAQKGYKVTGIDFSKRSINYAQNRN
                     KETNLNINYLFQSYLNMNYNDEFDLATLIYCDYGALSTENRRLLMEKIYDSLKPGGKL
                     ILDVFTINKYNNFEEIKYWEINEDGGFWSNEKYMCLQDNCKYNDYNTLEQTLVITEKD
                     ENVFYVWNHYFSKESFLLEVENIGFKSVEFFSNVKGEAYSDDSMTMGLVLQK"
     gene            complement(7515..8417)
                     /locus_tag="PC466_003072"
     CDS             complement(7515..8417)
                     /locus_tag="PC466_003072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HDF2770433.1"
                     /translation="MYNKIKYIPINCEIACNKLKRSMPYKWDLNIYRGCEHGCKYCYA
                     IYSHKYINSNNYFEEIYVKTNIVEKLERQLKSSKWKKEVINIGGVTDSYQPIEADYKI
                     MPEILNLLIKYKTPAIISTKSDLILRDYDLIDKLSRITYINVASTITTVNEDTQRLIE
                     PNGVDSMRRFKMLKEFRKTNASVGLHIMPIIPYITDDFDNINSLFRHAKECNVHYVLP
                     GTLYLRGITRGVFFDFVKKEFPELFDKLSILYSAGSLNREYKNQLYKMVNELRYKYSL
                     SSSYSKIMKEKLKNSGDGQISFFD"
     gene            complement(8467..8928)
                     /locus_tag="PC466_003073"
     CDS             complement(8467..8928)
                     /locus_tag="PC466_003073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine dimer DNA glycosylase/endonuclease V"
                     /protein_id="HDF2770434.1"
                     /translation="MRLWHKDLIDVLPKNQLVSQWRELLAIKGSIDKKGTPNHLLVNK
                     VLNYSIDEFKFYTKIVHDEMLKRNYKPNELKYTSILKWKNRNFANDISNEHSLNLENL
                     YDDWHNKMYLKQCLYNLEEKATCGGIPINEWNILLCKYSKDYELWSGNIMF"
     gene            complement(8980..9435)
                     /gene="def"
                     /locus_tag="PC466_003074"
     CDS             complement(8980..9435)
                     /gene="def"
                     /locus_tag="PC466_003074"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HDF2770435.1"
                     /translation="MAIRKIRTFDDEILRKKSKYVENVDNKIREILNDMAETMYNTPN
                     GGGLAACQVGVLKRLVVIDLGEGLIKLVNPEIIKQEGEQIVVEGCLSFPEVWGKLKRP
                     KKVTVQALNEYGEKIEIKGSGFMAKCLCHEIDHLNGIVFTDKIIEHVKL"
     gene            complement(9407..9670)
                     /locus_tag="PC466_003075"
     CDS             complement(9407..9670)
                     /locus_tag="PC466_003075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2770436.1"
                     /translation="MKNKIKILREKLGLTQEQLGRLVGTSRQAINAIETGKNEPSIWL
                     AYDISRIFNEPIESVFLFEESERKSRAQISRGEYYGYKKDKNI"
     gene            complement(9767..10483)
                     /locus_tag="PC466_003076"
     CDS             complement(9767..10483)
                     /locus_tag="PC466_003076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2770437.1"
                     /translation="MIKIINAFKQEFEQIKRDAMLFIVCVSPILCGVFIKFGIPLIQN
                     ISLNKFYYQLNLEPYFLMFDLLLAFITPFMFFFASTMVILGEIDDSISRYLIVTPLGK
                     TGYLISRFGIPGTLAFIISMILLIFFSLTKISFLLNLSISLLVLLQGVIISILVISLS
                     SNKLEGMVITKFSGVFMMGILAPFFILNKAQYILFFLPTFWISKAFKEDNYIYMFISI
                     VISLIWILLLFKKFSKKIVK"
     gene            complement(10480..11157)
                     /locus_tag="PC466_003077"
     CDS             complement(10480..11157)
                     /locus_tag="PC466_003077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2770438.1"
                     /translation="MRLKNLILGDIKFQFKYGFYFLYLFLSIIYICIINVFPTFMREK
                     IAIIMIYSDPAAMGLFFMGAIVLLEKSQRVLNSLAVSPVKVSEYILSKVISLGVISSI
                     VAMFIAITLNLDNIIISTIGTFFSSIIFSLLGLILASKASSLNQFIVLSIPIEIICFI
                     PPILNVLLDTKSYANLYPFNICISLISGDKNFIMINILISIIIIIYFITYYFICSSWK
                     KVGGVKL"
     gene            complement(11154..11999)
                     /locus_tag="PC466_003078"
     CDS             complement(11154..11999)
                     /locus_tag="PC466_003078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2770439.1"
                     /translation="MIKVDDLSFSYTDRNFLQNINFEVEKGEILGFLGPSGAGKSTLQ
                     KILIGMITNYGGSVIVNGVESKRHSNKFYENIGVDFEFPSLYEKLTAIENLKYFGSLY
                     SKKLLSIDELLKSVGLENEANKRVSEYSKGMKSRLNFIKALLHNPDILFLDEPTSGLD
                     PSNSKVMKDIILSEKSKGKTIILTTHNMLDATELCDRVAFIVNGKISALDTPHNLIMS
                     KGAIKVRYTYFDNGEKTSECFLNNTANDKNLNMLIKKNKLLSIHSSEPTLNDIFIEIT
                     GRNLQ"
     gene            complement(12113..12703)
                     /locus_tag="PC466_003079"
     CDS             complement(12113..12703)
                     /locus_tag="PC466_003079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2770440.1"
                     /translation="MPKSYSDKEREYIIKRLKEEARLCMEQYGIRKTTVDELVKRVKI
                     PKGTFYLFFQSKELLFFEVLRDIHDSIQKEILYEINRVDESITCEQLTDIFMKFYRMV
                     DSTSILNLMINGEFEILVRKLPDSIIEEHFRHDDFEIGEIISCIPNAKNKDIESFSGA
                     FRVVFLTMLYKREVGSNCFEDALRLMINGLVIQLME"
     gene            12992..13225
                     /locus_tag="PC466_003080"
     CDS             12992..13225
                     /locus_tag="PC466_003080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HDF2770441.1"
                     /translation="MATTTKNRFYDYVQENLNKYVEVHSYFSSCPLYGEIIEADSLSI
                     TLCSRYIDESNPTLNETYTLYLPLSSIISIRTL"
BASE COUNT         4526 a         2160 c         1230 g         5329 t
ORIGIN      
        1 tggaaatata cttaattgaa aacttaaatt tatttccttg tgttatcaag atttcatgct
       61 taccatttcc aatatcatgc tcaccaactt ttgatgtgca taaactattt caagtaaaaa
      121 tgcacaacct atcctttttg ataggaaaaa gcagtcaatc ataaatatca actgctttta
      181 tgtactgaat atcaagttat agacaagctg gaatttattt tgagggtttt tctttctcct
      241 taactaaatt gctttcaaaa gtaaccttta caactgcatg atttatttta attccggtaa
      301 agcatatagc atactctttc tctttttgta tattagaaag agaaattgcg aatgtatcat
      361 tatcaacgct tccatgccat gtattactcc ataaagtttc atctgtttta ttgtccttta
      421 tttccacaat accactatct ccatccattt taaaagaaat ctctgtgtct aaaacatcta
      481 tatcattaga cacacaaaac aaacgtgcat taacaaatgg gtctgaagta tcataatttt
      541 tatctaagtc catttcaatg gttgtttgtc ctgattcttt gttgtttaaa ttattatatt
      601 tactttcatt gcttttttta caagctgtca agctaaccac actaatgata ctaattaaaa
      661 taataactaa ttttttcata gaatttatct cctttacaat ttctaatttt taaccctaca
      721 aactataata ttaaactaat ctactatttt acatcaaatt tttcaatcat tcagccttta
      781 ccttttctca ttttaattgc aaatatgcta aataattttg gaattttaat tattgtagta
      841 tcttaaattg gtttataaca tattatgaaa atttaagagt caagtaactt atttaaaaat
      901 acacaaaatt atactttatt gtataaaaaa agagattata atttatacaa gtaaaataaa
      961 ctttattatt ttactcttct atataacctc ttttctatat atctattcaa ataatttagc
     1021 tcctaaactc acaaacattt gtaaaatcaa aaatgctttt gtgtctatct tatgattact
     1081 ttgtaaaatc tcttttgcat cttcttgcga aattaaaagc gcttcaatct cttcatctgg
     1141 ttctaaaaat tcatctgtta tatcaccatc acatatacaa taaacaaagg caacagattc
     1201 atcactcatt ccaggagata aataaacttt atcaatactt ttattttttt taatttctaa
     1261 aagagtaagt cctgtttctt ctctaagttc tctttcaaca gaaatatcta tagactctcc
     1321 ttcatcaaca agacctgctg gtaactcgta tatatatcca ttaataggta ctctaaattg
     1381 tcttattaaa attaattttt tactactttt atgaagccca actattacaa ctgcatctac
     1441 actatcttct tcattcttca aataaatatt ttttaattgc tcactacttt ttcttgatgc
     1501 taccatccaa accttatctt catctaattt gtttttatac tctatttcaa aaagtcctat
     1561 aaacttattt tcaatcattg gatttacatt ctttattata gtttttttca aatttactac
     1621 gacctttctt ttttaatacc tttttaacat cattaagtaa atataatatc ttaacaagta
     1681 ttcaacaact tattatattt ccatttcagg attatcttta tctacaaaac ctactttgat
     1741 ttcacaatta aatatttcct ttaacaattt tgctaattct tctcttgcac tcattacctt
     1801 atctaaatta gcatcagtaa aaccatctat aggaaaaaat atattttttg agctattagt
     1861 aatttttcct tcctctcctt gtctccatat ccatcttcta gtttttacca tgtctccaac
     1921 tgaataaatt aattctcctt cttccattaa ttcaacatca gtttctccaa atggtacaaa
     1981 tttatcccct tttttagaaa atctaacata tacatcatca tttctaaaat ccatatcatg
     2041 agcacccatt ggaagtaaat attttaaaga aatagagttt cctaaatcta caataggatt
     2101 tatatgagga agtttcttat tcttagcaac ccttgttgtc attgcttcta tcgaactcat
     2161 aaatttattt gggttcatgc ctagacttct aaatgcctct ctatatggta taatttcttc
     2221 tgattccttt acttttttat ctttgaagta atcttctact ctatctatac ttatatctaa
     2281 aaggttgctt attctttcta tttctttagt attatctatt ccttttgcaa ctactacacc
     2341 aaagcataca ttttctaatt tatcaaaaac ttctttttct actataaatt tcattttgct
     2401 ttatcctcct gttattttac attattttct aaatagattt tatcactttg tgtcttataa
     2461 atataccccc tatttgctaa ttgtttaatt tttttaaatt ttccaattaa tattatattt
     2521 attcttatca gatattttat atgtactaat tacaaattta actttccaaa acaaatatct
     2581 tgttttataa tgtataatat atttttatgg aggcaagact gtgaaaaatt ttattctaat
     2641 atattttata gtgattaatt ctattgcttt cttttcaatg tacatagata agaaaagagc
     2701 aattagaaac gaatggagaa taaaagaagc tactcttatg tctatagcag taattggagg
     2761 tagtataggt tctatgattg gaatgtattc ttttagacat aaaactaaac acattaaatt
     2821 tacatttggt ataccattta tactattttt acaattttta ttagtatatt tttatatttt
     2881 aaagtaattg aaatataaaa ccttattctt ttcaataaat taaggtgtat aaaattaaaa
     2941 actttataca cctttttcta gcaattatta aaaagatatt taattaaaat taatgaccct
     3001 tatgtttagc ttttctcttt tcttgtttca aattaaatat tctttctttt tcttcttctt
     3061 ttctattttt agctaggttt tttctatcct gttttctttc ttcatattga agcttaagag
     3121 cattttgagc cttagtccct atagtttctt tttcttgttc cttttttact tttctctgca
     3181 ttcttttgta tccaatgttg tctttggtca catttttttc taatttaatg ctaccaaaat
     3241 ctaatgagaa aaatctttca agtataaatt catacacttc tacttcttta ggttctgctc
     3301 caaaaactac cctacatgct tcatattttt taccatcttg tctttcaaat atacctaccc
     3361 aaaatggttc ttcaaataag actgttaatt ttccactaat tttgtccatc gctagttcct
     3421 ccttaaatta ctttctaaag aacggacaac caaggaggca ggttactgac agctattgct
     3481 gcgtctggac taccaaccag actgtgtttt tatctttata gattaaatat tatctttttt
     3541 aatcatgctt gtcaatctta gtatcaacat ctatcatatt gatttaagtg aaatcaagct
     3601 ttttaactct actttattat tgttaacact aagaaaatta attatttttc ataataaatt
     3661 agttattata cttatttaaa tatcaatctt tattgttccc tgcataaaca agactgcttc
     3721 accagaaatt tttacagtat tatccttcaa cacttcacac tgaattatac caccacgatt
     3781 agaaagttga gcagctacca ttttgtgttt tcccaacttt tcagaccagt atggaataaa
     3841 attacaatgt gatgaaccag taacagggtc ttctgaatct aattctggac aaaaatatct
     3901 tgatacaaaa tctgtattac ttccttgtgg tgtgattatt atacctaacc agtctgtcaa
     3961 tttacgcaat tgtgcgtaat taggtttata atttataact tcttgttcac tgtttagcaa
     4021 taagattaaa tctcttgaag aatagacagc acttggtaca cagcctatca aattagcttg
     4081 ttatggtgat aactctattt caataggcat tatttctgga aatatcattt catatagatt
     4141 tccatttcgt gtaacttcaa gctttccact ttgagtaaag aaatctatcc tttttacatt
     4201 aacatcaata aaatttgata ttacataagc tgctgctaaa gttgcatgac cacataaatc
     4261 aatttctgct ttaggagtaa accatcgtaa ttcataattt cctttacctt taactacaaa
     4321 tgctgtttct ggtaaattgt tttcttctgc tattttctgc attaactcta aaggtattat
     4381 tctgtcaaga acacaaactc cagcaggatt tcctttaaat agtttagttg caaatgaatc
     4441 aactatgtag tattccatta tttgacctct ctttccaaca taaaatatac atcaatttac
     4501 attcaataaa actttaaatt tcttacatat attttttaat attgctctgc tcaacaactt
     4561 ttttacctaa caatgtaatt gctttttttg cacaattatt tacacaacga taacacattg
     4621 tacattgccc atttgcaaca atcatacaat ttttaattac tagattcttc attggacata
     4681 aattaacaca tttaccacat acaatacatt cctcagtatt aatttttagt ttatctgtat
     4741 acatatttgt tttattgata aaatacaatc gttgtccaaa taaccctaca atatgactca
     4801 aaaaacctaa cccttctttt ggtggtgacc catgtttcag ttttttagca gctttagtta
     4861 ctttcttttc tgcttttatt acaagctttt tattatactc taaagaatgt tttaatacct
     4921 tttcatctcc tatactatct ggcatcttca catgtaatcc accaacagtt atagcaccgt
     4981 atttttttaa tattctagct aacacaccag agccatctcc actaaataga gccatagttg
     5041 caataataaa aacacgttta ccattccaca aagttgaatg atttattata aaatctttca
     5101 atatttttgg cacattacta tattgcacag gataactaaa aataatattc tcatgattat
     5161 tgatgtgctg taaaagttca ttatcttcaa tagaataaga atttgctgtt atatcatatt
     5221 cttgtaaaaa tttttctaca cagtatcttg aatttcctgt tccactaaaa tatattccta
     5281 tcatagtact tctcctaata gctaagatta tatagctcta ttcttaaaat tctgactttt
     5341 tatattatct aaattaagta gtttatttaa ataatataaa cttaattcaa caagttacct
     5401 actgaacctc ccatgactaa agtcataggg ttcctgcttg atagaatttt acataatcaa
     5461 tttactaaat acttgtctaa ttcttttttt atcattttaa atatacattt taataatatt
     5521 agtaagctat acttccttaa gcatatattt tccctaaagt aaaactattg atgattattc
     5581 cattatataa cctaattata aatttagtaa gttcatcaca tactataccc ttaattctca
     5641 attataaagt tccctaaaaa atatttgaaa atttaactat gaaaagattt cctattgcct
     5701 aatatgtata agtaaggagt actatatagt actccttata ttgtactctt ataacattga
     5761 taccttaata ttattttaat cttaatcatt attgatttga tttaaaatta taaataggtt
     5821 ccaatatttt aattatgtca actatatctc ttatagtttt aataatctca tcaattggtt
     5881 tatgtgcttg ttgcacttta tcaatagtat taattaaatc catttacaca tctagcacct
     5941 gtatggcaat ttagcattat ccttatctta tactttgttg taaattcttg attacataat
     6001 tctattatct aacttatagc tgtgcaatct acattatctg taaatatctt tgctttatat
     6061 attttccctg aacctctaac attaatataa cagccttttt gctatacact tttaactata
     6121 tacttaattt taataacatt acttgtttat aaaaatatac tatagataaa tttcacataa
     6181 aaataataat tcaagtattg atttttatat aagaaaattt gtaatgtact aaaaataaca
     6241 taaaagtttc catttttcaa tatgtaagct tttcttatgt tattttattg ttaaaggttt
     6301 caagttttta tttattcatt ttaaaaaaat tattattttt gtaaaactaa tcccatagtc
     6361 atactatcgt cagaatatgc ttcaccctta acattactaa aaaactcaac agacttaaat
     6421 ccaatatttt caacttctaa taagaaactt tcttttgaaa aatagtgatt ccaaacataa
     6481 aatacatttt catctttttc ggttattaca agagtttgtt ctaatgtatt ataatcattg
     6541 tatttacaat tatcttgtag acacatatat ttttcattac tccaaaatcc tccatcttca
     6601 tttatttccc aatatttaat ttcctcaaaa ttattgtatt tatttattgt aaatacatct
     6661 aatattaatt ttcctccagg ttttaaacta tcataaattt tttccattaa taaccttcta
     6721 ttttcagttg acaaagctcc ataatcacaa taaattaaag tagccaaatc aaattcatca
     6781 ttatagttca tatttaaata actttgaaac aagtaattta tgtttaaatt agtctcctta
     6841 tttctatttt gtgcatagtt aatagaacgt tttgagaaat caattccagt taccttataa
     6901 cctttttgtg caaatttctc tgcatataaa cctggaccac aacctaaatc aagtaaatta
     6961 ggataattaa ctggatttgc aactgtaact atccaattta cagaatcctc gataaagtta
     7021 aaatttctac ttgctccttc aaaattagtg tctaaatgtg cttttaataa ttgttttgaa
     7081 atatactcat catcccaaaa attaatttca ctttgtttat aaagctctgg tctttctaaa
     7141 tacatacata atttgtttaa caaaacatac cactccttaa aatttatttt taaaataaaa
     7201 aaaccacaga gtttactctg tggtttaact tcaaaaagat gagtttaaat aagagtaaaa
     7261 tagaaccaaa tatttttaag cacaacaata aaactatagc tttactttgt ttgcttatta
     7321 aatttgattt tattcactct tttccagcaa tacttatatc aacgatttta tgatatcaaa
     7381 tatcaccgaa caacatcatc ctttcatatt tttattttat gaatcaatta tatatttaaa
     7441 ttttatattt gtcaataaat tttaatttta ataaatttta atcatcatag taaaaaaaaa
     7501 ttttttatat aaaactaatc aaaaaaagat atctgtccat ctcctgagtt ttttaacttt
     7561 tccttcatta ttttagagta actgcttgat agagaatatt tatatctaag ttcattaacc
     7621 attttataca attgattttt atactcccta ttaagtgaac ctgcactata tagtattgat
     7681 aatttatcaa ataattcagg aaactctttt ttaacaaagt caaaaaaaac acctctagtt
     7741 atacccctta agtataaagt cccaggtaaa acataatgta cattacattc ttttgcatgt
     7801 ctaaatagcg aatttatatt atcaaaatca tctgtaatat atggtataat tggcataata
     7861 tgtagaccaa ctgatgcgtt agtttttcta aattctttta acattttaaa tcgtctcatt
     7921 gaatccacac catttggctc aataagcctt tgtgtatctt catttactgt ggtaattgta
     7981 gatgctacat tgatatatgt aatcctagat agcttatcaa ttaaatcgta atctcttaaa
     8041 attaaatctg actttgtaga aataatagct ggtgtcttgt attttatcag caggtttaat
     8101 atttctggca taattttata gtcagcttct attggttgat aactatctgt aactcctcct
     8161 atattgatta cttctttctt ccatttactg cttttaagtt gtctctcaag tttttctact
     8221 atatttgttt ttacataaat ctcttcaaaa taattattgg agttaatgta cttatgagag
     8281 taaatagcat aacaatattt acatccatgc tcacatccac gataaatatt taaatcccat
     8341 ttatatggca tactcctttt taatttatta caagctattt cacaatttat tggaatatat
     8401 tttattttat tatacaaata atcacctctt tatatacaat aatactataa tgttaatcta
     8461 tagtaattaa aacatgatat ttccagacca caattcataa tctttactat atttacaaag
     8521 taatatattc cattcattta ttggtattcc tccacatgtt gctttttctt ctaaattata
     8581 taagcattgc tttaaataca ttttattatg ccaatcatca tataaatttt ctaaatttaa
     8641 actatgttca ttagatatat catttgcaaa atttctattt ttccatttta atatacttgt
     8701 atatttaagt tcattaggtt tataatttct ttttaacatt tcatcatgta caatttttgt
     8761 ataaaattta aattcatcta tactataatt caatacttta ttcactaata gatggtttgg
     8821 agtacctttt ttatctatag aaccttttat agcaagtagc tctctccatt gacttactaa
     8881 ttgattttta ggtaatacat caattaaatc cttatgccat aatctcataa tttaactcct
     8941 tactataaaa tattttataa attcaataac caatctatct tacaatttta catgttcaat
     9001 aattttatct gtaaaaacta taccatttaa atggtctatc tcatgacaaa gacattttgc
     9061 cataaaacct gaacctttaa tttctatttt ctcaccgtat tcgtttagag cttgcactgt
     9121 aacttttttt ggtcttttta atttacccca tacttctgga aaacttaaac atccttcaac
     9181 aacaatttgt tccccttctt gtttaataat ttcaggatta acaagcttaa taagtccttc
     9241 tcctaaatct ataacaacta atcgctttaa tactcctact tggcatgcag ctaatcctcc
     9301 tccatttgga gtattgtaca tggtctctgc catgtcattt aatatttctc ttatcttatt
     9361 atctacgttt tctacatact tactcttttt tcttaaaatt tcatcatcaa atgttcttat
     9421 ctttcttata gccataatat tctcccctac ttatctgtgc tcttgatttt ctttcacttt
     9481 cttcaaataa aaatacactt tcaattggtt cattaaaaat tcttgaaata tcatatgcca
     9541 accatattga aggttcattt ttaccagttt ctatagcatt tatagcctgt ctagatgttc
     9601 caactaatct tcctagttgt tcttgtgtca atcctaattt ttctcttaat atctttattt
     9661 tatttttcat atttgctcca ttcatgtaag gttaacttta catcttaaat gtaacatttt
     9721 tcaacattac tgtcaagtca accttacatt tatatattaa attttcttat ttaactattt
     9781 ttttactaaa ctttttaaat aataataaaa tccatattaa tgatataaca attgaaataa
     9841 acatatagat ataattatct tccttaaatg ccttcgatat ccaaaaagtt ggtaagaaga
     9901 acagaatata ttgtgcttta tttaaaataa aaaatggtgc taaaataccc atcataaaaa
     9961 cacctgagaa tttcgtaatt accattcctt ctagtttatt tgatgataaa gaaatcacta
    10021 gtattgatat aataactcct tgtaataaaa ctaataaaga aattgataag tttaacaaga
    10081 aagaaatttt agttagagaa aaaaagataa gtagaatcat actaataata aatgctaagg
    10141 tacctggtat tccaaatcgt gaaataagat aaccagtttt accaagcgga gttactatta
    10201 aatatcttga aatgctgtca tcaatttctc ccaatatgac cattgtagaa gcaaaaaaga
    10261 acataaaagg tgtaataaaa gctaaaagta aatcaaacat caagaaatac ggctctaaat
    10321 ttaattgata ataaaacttg ttaagtgata tattctgtat taatggtatt ccaaatttta
    10381 taaatactcc acataatatt ggagaaacac atactataaa aagcatagca tctctcttaa
    10441 tttgttcaaa ctcttgttta aacgcattta taatctttat catagtttta ctccacctac
    10501 ctttttccaa ctgctacaaa taaaataata agttataaaa taaattatta ttataattga
    10561 tattaaaata ttaatcatta taaaattttt atctccacta ataagagaaa tacatatatt
    10621 aaaagggtac aaatttgcat atgattttgt gtcaagaagt acattgagta ttggtggaat
    10681 aaagcatata atctcaatag gaatacttaa aacaataaac tgattcaaac tagatgcttt
    10741 acttgcaagt atcaatccaa gcaaagaaaa tataatagaa gaaaaaaagg tacctatagt
    10801 tgatattata atattatcta aatttaatgt aatagcaata aacatagcta caatactaga
    10861 tattactcct aatgaaatta cctttgataa aatatactca gatactttta ctggagatac
    10921 agctaaggaa tttaaaaccc tttgactttt ctcaagaagt acaatagctc ccataaaaaa
    10981 caatcccatt gctgctgggt cagaataaat cataattata gctatttttt ctctcataaa
    11041 agttggaaat acattgataa tacaaatata tataatactt aaaaaaagat ataaaaaata
    11101 aaaaccatac ttaaattgaa actttatatc tcctaaaata agatttttta gcctcattgt
    11161 aaattcctcc ctgttatctc aataaaaata tcatttaatg ttggttcact actatgtatt
    11221 gataaaagtt tatttttctt aataagcata ttcaaatttt tatcattagc agtattgttc
    11281 agaaaacatt cagaagtttt ttctccatta tcaaagtaag tatatctaac tttaatagct
    11341 ccttttgaca taataagatt atgtggtgta tctaaagcag atattttacc atttacaatg
    11401 aacgctactc tgtcacaaag ctccgttgca tctaacatgt tatgagttgt taaaataata
    11461 gttttacctt tagatttttc tgataaaatt atatctttca taaccttgct atttgacggg
    11521 tcaagaccac ttgttggttc atctaaaaat aaaatatctg gattatgtaa taaagctttt
    11581 ataaaattta atcgagattt catacctttt gaatactcag ataccctttt atttgcttca
    11641 ttttctagtc ctactgattt taataactca tcaatagata gtagtttttt agaatataga
    11701 gacccaaaat attttaaatt ttctattgca gtcaactttt catataaact aggaaattca
    11761 aaatcaactc ctatattttc ataaaattta tttgagtgtc ttttactctc tactccattt
    11821 acaatgacac ttcctccata attagttatc attccaatta gaatcttttg taatgtagat
    11881 tttcctgcac ctgatggtcc taaaaatcct agtatttccc ctttttctac ttcaaagtta
    11941 atattttgta aaaaatttct atctgtataa ctaaatgata aatcatcaac tttaatcatt
    12001 caatatcacc ctttcaaatt tttgactatt ttgactatat ggtcaataaa atataatttt
    12061 tttgtttgtt aataattttt aataaaagtt attagcaaac aaaatttaaa ttctattcca
    12121 taagttgtat aactaatccg tttatcatta atcttaaagc atcttcaaaa caattacttc
    12181 caacctcgcg cttatatagc atggtaagaa aaactactct aaatgctcca ctaaagcttt
    12241 ctatgtcttt attttttgca tttggtatgc aagatataat ctctccaatt tcaaagtcat
    12301 catgtctaaa gtgttcttca attatagaat ctggtaactt tctcaccaat atctcaaatt
    12361 ctccatttat catgagattt aaaattgaag tactatcaac catcctatag aatttcataa
    12421 atatatctgt caattgttca catgtaatac tttcatctac tctatttatc tcatataaga
    12481 tttctttttg tatagagtca tgtatatctc tcaatacctc aaaaaagagc aattcttttg
    12541 attgaaaaaa tagataaaaa gttccttttg gtatttttac ccgttttaca agctcatcaa
    12601 cagtagtttt tctaatacca tattgctcca tacacaatct tgcttcttct ttaagtcttt
    12661 ttattatata ctctctttct ttatcagaat acgatttagg catctttttc ctccagtttg
    12721 actaaaataa tttatatagt caatataata ctttttctat ctaatgtcaa tagtattatt
    12781 agtatattta aaaataagct taaaaacttt cgaaaattct gaattttata tagcattttt
    12841 tattatctag tgttataatt aagatataaa taatatatta ttctaatttt catatctatt
    12901 tgcttatttt ttaacttagt ttctaataga agtactcata tttatctttt taaaagtttc
    12961 aactttaata aaaaataaag gagttgattt tatggctact actacaaaaa accgttttta
    13021 cgattatgtt caagaaaact taaataaata tgttgaagta cattcttact ttagcagttg
    13081 tcctctatat ggtgaaatta tagaagcaga tagcttatca attacacttt gctcaagata
    13141 tatagatgaa tctaatccaa ctttaaatga aacttacaca ttatatttac cattaagttc
    13201 aataatatct attagaacac tataaaaagt taattaaata tgggt
//
LOCUS       DAMJYN010000094        13022 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.098, whole genome shotgun sequence.
ACCESSION   DAMJYN010000094 DAMJYN010000000
VERSION     DAMJYN010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13022)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13022)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13022
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.098"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            165..1316
                     /locus_tag="PC466_003081"
     CDS             165..1316
                     /locus_tag="PC466_003081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004452985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2770442.1"
                     /translation="MELRPRSAKLEEFDKVIELINYVFRISRNHKPTMMEEFPLLLSK
                     NNIENMIIISEDDKVVSDVNYLIQDVSIQGNRLKVAAIGGVCTHPDYEKRGYSSKILD
                     KVEEKMFYDGVDIVIISGTRSLYSRRNCSLVKSFYKYTIKPEDVKIAYEIVEFDETNF
                     EKDDDLDKMLELYNQNSTRFIRTRDEFQKLLHAATIAWGPIGYKKVFIKENNNIIGYL
                     IIRTIKKEDSTVGEVAEIGLNSVNVENILKYVANKFGLEYLNYKVHVKNLKDQLKCNG
                     TESLDYQQGTMKIINFTKLCDSLRSYFSQYVDFELLKYMEFKQVENKYIIKYKEEELV
                     IENLDKLNKLFFEKNEEQYNEFKHLKNIYEFATKAFPVDFPWTANLNYQ"
     gene            1434..2072
                     /locus_tag="PC466_003082"
     CDS             1434..2072
                     /locus_tag="PC466_003082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423639.1"
                     /note="Presence of a B(12) (cobalamin)-binding domain
                     implies dependence on cobalamin itself, in one of its
                     several forms, or in some unusual lineages, dependence on
                     a cobalamin-like analog; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin-dependent protein"
                     /protein_id="HDF2770443.1"
                     /translation="MDILDDIAECILNMGVDNIENLVKIAIDKNIDVEDIYEYGLNKG
                     MIGALDKFENKEYYLSEVIVCTDALNKGINLLKGTGKVKKKSKGVILMSVVEGDTHEI
                     GKNIVKVMVEATGYKVIDLGVNRKSEDIIEEAIKNNVDIIGLSSMMTTTMENMKSVID
                     ELNMIEIDKRPKVIIGGGPVSMEFAEEIGADGYSSNAPKAVKLINKLIGGEV"
     gene            2073..3095
                     /locus_tag="PC466_003083"
     CDS             2073..3095
                     /locus_tag="PC466_003083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase"
                     /protein_id="HDF2770444.1"
                     /translation="MFSDMTLLQYINSEDRGFFLPDMGTNGLFLINKKAYEVYDSVDL
                     QLELAKTMDKYFESDFIYSFCDGITFCETLGLETLRPDYDFPSVLTHTITDRDKLRKL
                     DVPDPYTSGRMPLNIESLSVISKSIKKPLYESIQGPFTLAGQLAGATQLLRCIITDKK
                     FVEELLEFTTELVRRYAVAANKAGAKYISIAEPTSVTLSKDRFDEYIVKNLNKIYNEL
                     DCWKGMHICGDTRELLDNMLSCNIDAVSLDQILDYEEIAPMIPRDIVLIGNLDPIKLL
                     GRSKPDKIRRETLKLLKKMRGYDNFLCDFGCNCLNTTPVENLQAAIKAGRINYKELDR
                     IDIDEL"
     gene            3085..3705
                     /locus_tag="PC466_003084"
     CDS             3085..3705
                     /locus_tag="PC466_003084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770445.1"
                     /translation="MNYNSNKNKYLLKDINLEDIFIDKNIVLKFLGYGNRKAPDTISE
                     IVEREIRNINDILDIKIYISEVDINKTPKECKKAFAVLYTIGDKIDIKMNDYMENCNM
                     MAGIALDKIGIVCLDYINEKIKMYLKGKYDSLKISHEIYPGDKDFEVERQKDIYNYVK
                     NKYNSIEIEINDYHQLSPIKSVAMLILMGDEENLESRCSKCPRKCF"
     gene            complement(3829..4515)
                     /locus_tag="PC466_003085"
     CDS             complement(3829..4515)
                     /locus_tag="PC466_003085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HDF2770446.1"
                     /translation="MKTYKFIFFDADDTLFDFKKSESHAFKKLLSEFDLEFNFENYIE
                     SYRNISDKLWLDLEKNIITLNELKLLRFELFANKISLDVDSETLSKMYLNFLGECTFL
                     IPGAIDILQYLKKKYTIVIITNGISAVQKKRLENSKIKGYIDGMVVSEELKISKPNPE
                     IFKYALKKFNCHDKSSALMIGNSLTSDVLGGINSGIDTCWLNSNNSINYTNHIPTYEI
                     NTLIELKKLL"
     gene            complement(4529..5074)
                     /locus_tag="PC466_003086"
     CDS             complement(4529..5074)
                     /locus_tag="PC466_003086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2770447.1"
                     /translation="MNDLNLGEKIAEVRKKQNLSIRDLAKLADVTPSLLSQIERGLAN
                     PSVNSLKSIASSLNVPLFTFFVSEVDKKNLIVRHDNRKKVILPGSKEVIYEILIPDSS
                     GNLEFAIMDLAPNTSSCIDRITHNGDEIAYVLEGEVKLFMDDDEFTLSKGDSVKVPLG
                     TKHKWQNDSNSESKVIFAVIL"
     gene            5302..6549
                     /locus_tag="PC466_003087"
     CDS             5302..6549
                     /locus_tag="PC466_003087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HDF2770448.1"
                     /translation="MQITTFGAIFGLLIAIILIIKKFQAVYSLMLGAFIGGLVGGANI
                     TQTVDFMANGAMNISPSILRALASGVLAGSLIKTGAVDKISEQIVKIFGEKRALFSIA
                     ISTMVLAGVGVNLDVSIITVAPIGLYIGRKLNYSKLSILLAMLGGGKAGNIISPNPNT
                     IAVADNFSVNLSSVMMANIIPAIIGVVITVILASILINKGNKVQSYEILEQREDLPSL
                     FKSLCGPIIAIFLLFLGNVSPIVIDPMIALPIGGIVTLIVTGNLNNSREYLAFGLSKM
                     QGVCILLLGTGTIAGIIQMSELQQSTIGALQFLNMPQFLLAPVSGILMSLATASSTAG
                     ATIASSTFHDAIINGGLSPISGASIVNAGSSVFEQLPHGSLFHTSSGSINMDIGERFK
                     LIPYEALIGIVMTIISTSIQLVL"
     gene            6636..8630
                     /locus_tag="PC466_003088"
     CDS             6636..8630
                     /locus_tag="PC466_003088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HDF2770449.1"
                     /translation="MNKKKIVIIGIIYSFLVVFSLTNMYVNMEYNLNVFEYIKKSLPF
                     TEEEKKWLEKHKNLIYSSDQSSPPLRYKGKEDGQYKGIIVDLINSLSIQIGRDFYFKP
                     NNWWKESFVNSIDDSIKFFDLIPSKERANKFIFTDPIYTLSANILKDKKSQDINSYMD
                     LKGKTVAIPEGDYSINFLKQKIQDINILLTPDIKTGVNHLMSGKVDAVVGDEPVLRYY
                     INNYGLSNKYSVLSNPIYTKKAVLAVPKQYEELVSILNKGIFKLQKNGVYKDLKKKWY
                     STYNEVDDILYERGIVPSIYLFIGIILISIYVFYSYTYLLKIEIKRKTEQVIENKKTL
                     EATFNSITDIIMLVDENNNIVESNKVLYDFMGEMSYKIADLISMIKGVIKNTFSENTN
                     KTSEIEIYNKILKINTFPVEYKKNNTEYIVVLIKDITNEKIVEAKLLRENKMISIGQL
                     ASGVAHEIRNPLGIIRNNCYLLKDNVTMEEVNDCVKSIESNVDRASNIITNLLNFARI
                     SDDNLEHINIRNFIENIVKLQYKMLQLKNVEIKIDCEHNLVCYINGESLKHVFINLIS
                     NSIDAIHQDGKIIIYCYEKNHCLFIDFKDNGEGIKEDALKDIFNPFYTTKPIGEGTGL
                     GLYITYNEIKKNNGDISVESKLGVGTCFHIKIPLNKEVTI"
     gene            8630..9952
                     /locus_tag="PC466_003089"
     CDS             8630..9952
                     /locus_tag="PC466_003089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent Fis family transcriptional
                     regulator"
                     /protein_id="HDF2770450.1"
                     /translation="MKILLVDDELEYGVVMKKILQKKGYLVDIALSGEEAINIIKKDK
                     NYDLVLSDVMMKNMDGVQLLDRIKSINRDIEVILVTGYGSIENAVDAMKRGALSYFIK
                     SNPIENLLEEVEKVKASKISVSVQKNNFEFTLESKNRDFNNIIKIAKKAACKDVNILI
                     LGESGVGKDILARYIHSISPRKNEIFVPVNCCSFSENLLESELFGHEKGSFTGAVDSR
                     KGRFELSNKGTLFLDEIGDIPLNVQVKLLRTLEDKSIERIGSNKSIKVDFRLICAMNK
                     EPKVEISNGNIREDFFYRISTITITIPPLRKRREDLTTLIEFFLNKYQIEHDKKIHSI
                     DKEVKDFLLNYNYPGNIRELKNIINRLVVLSEEGNLSKDNLNLISNNVYIDDKISIRP
                     LREIRKEFECEYIEKVLSLCGNNISNTAKKLEISRRQLTNKISEYNIK"
     gene            10231..11517
                     /locus_tag="PC466_003090"
     CDS             10231..11517
                     /locus_tag="PC466_003090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006807454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase component B
                     subunit"
                     /protein_id="HDF2770451.1"
                     /translation="MKLELGNIFIKNVEFGEKTEVKDGVLYISSEEIEKIVLEDERIV
                     SVNVELARPGESIRIAPVKDVIEPRVKIGDESKIFPGIINKVKTVGSGRTHVLLGACV
                     VTCGNIVGFQEGVIDMSGPTAKYTPFSKTNNICIVIKAKDGIDTHDYEEAARIAGLKI
                     GAYVGEAGREVEPDEVIVYETKPLLKQVKEYPDLPTVAYVHMLQSQGLLHDTYYYGVD
                     AKQIVPTFMYPTEIMDGAIISGNCVAPCDKVTTFHHLNNPVIHDLYKRHGKDLNFIGV
                     ILTNENVFLVDKERSSDMVAKLIEFLGVDGVLVTEEGYGNPDTDLMMNCRKCSEVGAN
                     VVLITDEFPGKDGKSQSIADATKEADAVVSCGQGNLVVHFPAMEKIIGTLDYVEMMIG
                     GYKGCLNEDGSMDAELQIIIASTIANGYNHLTARYY"
     gene            11603..12910
                     /gene="grdB"
                     /locus_tag="PC466_003091"
     CDS             11603..12910
                     /gene="grdB"
                     /locus_tag="PC466_003091"
                     /EC_number="1.21.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012158817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:12650..12652,aa:Sec)
                     /transl_table=11
                     /product="glycine reductase complex selenoprotein B"
                     /protein_id="HDF2770452.1"
                     /translation="MSKIRVVHYINNFFAGIGGEEKADIPPEKRAGVVGPGIAFQSQF
                     NDDAEIISTVICGDTYFGENIESATQELLKMIKEESPDLFIAGPAFNAGRYGVACGTI
                     CKAVEEELNIPVVTGMYKENPGVDMFKLDLHIVSTGNSAASLRKVVPIMTKLGLKLVR
                     GEEIGPPEEEGYIMRGIRKNFFHELRGSERAIDMLVKKMKGESFETEYPMPEFDRVTP
                     MKPVKDLSKIKLALVTSGGIVPIDNPDKIESSSATKYGIYDLTDMDSMSNKEFTTIHG
                     GYDRAYVLENPNLVVPLDVVRELEKEGVIGELVDYFITTTGTGTSVGNSKRFGEEFSK
                     KLLEDDVDAVILTSTUGTCTRCGATMVKEIERAGIAVVHICTVVPISLTIGANRIVPA
                     VGIPYPLGNPMLGEEESKKIRKNIVLKALNALTEDIEEQTVFE"
BASE COUNT         5227 a         1301 c         2304 g         4190 t
ORIGIN      
        1 tttataagtt taactataaa ttaggtttat attttataaa aatttgttaa aaaaaacaat
       61 taaaaattgt aaagaaaaaa gatataatta gaactgtagt aataaatgtt ttattataga
      121 taatagagtt ttaagtatct taaataatat ttggaggaat atgaatggaa ttaagaccaa
      181 gaagtgcaaa attagaagaa tttgataaag taatagaatt aataaactat gtatttagaa
      241 tatcaagaaa tcataagcca actatgatgg aagaatttcc tcttttacta agtaaaaata
      301 atatagaaaa tatgattata atatcagaag atgataaagt ggtttctgat gtaaactatc
      361 taattcaaga tgtatctatt caaggaaata gattgaaggt tgcagctata ggtggagtat
      421 gtactcatcc agattatgaa aagagaggct attcatctaa gatattggat aaagtagaag
      481 aaaaaatgtt ttatgatggt gtagatattg taattatatc aggaacaaga agtctataca
      541 gtagaagaaa ttgtagtttg gtaaagagtt tttataaata tacaataaaa cctgaagatg
      601 taaaaatagc atatgaaata gttgaatttg atgaaactaa ttttgaaaaa gatgatgatt
      661 tagataaaat gcttgaacta tataatcaaa atagtactag atttataaga acgagagatg
      721 agtttcaaaa actattgcat gcagcaacta ttgcctgggg accaattggt tacaagaagg
      781 tatttataaa ggaaaataat aatataatag gatatttgat aataagaaca ataaaaaaag
      841 aagattctac tgtaggagaa gttgctgaaa tagggttaaa ctctgtaaat gttgaaaata
      901 tattgaaata tgttgcaaat aaatttggat tagaatattt aaattataaa gtacatgtga
      961 aaaatcttaa agaccagttg aaatgtaatg ggacagaatc tttggactat caacaaggaa
     1021 ctatgaaaat aataaatttt actaagttgt gtgatagttt aagaagttat tttagtcaat
     1081 atgtagattt tgaattacta aaatacatgg aatttaaaca agttgaaaat aaatatatta
     1141 ttaaatacaa agaagaagaa cttgtaatag aaaatttgga taagcttaat aaactgtttt
     1201 ttgaaaaaaa tgaggaacag tataatgaat ttaaacatct aaaaaatata tatgaatttg
     1261 ctacaaaggc atttcctgta gattttccat ggactgcaaa tttaaattat caatagtttt
     1321 agatgatatt aaataaaatt gattgatacc tagagttagt ccttgttaaa taagagaaat
     1381 tattggatat tgaaaaagca attttgtaag taattagaaa ggatgagtat tatatggaca
     1441 tacttgatga tatagcagaa tgtatattaa atatgggtgt agataatata gagaatttag
     1501 taaaaattgc tatagataaa aatattgatg tggaagatat ttatgaatat ggtttaaaca
     1561 aaggtatgat aggagcttta gataagtttg agaataagga atactatctt tcagaagtta
     1621 tagtatgcac agatgcatta aataaaggta ttaatctttt gaagggaact ggaaaagtaa
     1681 agaaaaaatc aaagggagta attctgatgt ctgtagtaga aggagatact catgagatag
     1741 gaaaaaatat tgtaaaagta atggtagaag ccactggata taaggttatt gacttaggtg
     1801 taaatagaaa aagtgaagat ataatagaag aagctataaa aaacaatgta gatataatag
     1861 gcttatcttc aatgatgaca actacaatgg aaaatatgaa atcggttata gacgagctta
     1921 atatgattga gatagataaa agaccaaaag taataattgg tggaggacct gtaagtatgg
     1981 agtttgcaga agaaatagga gcagatggat acagttcaaa tgctccaaaa gcagttaaat
     2041 taataaacaa acttatagga ggtgaagttt aaatgttttc agatatgact ttacttcagt
     2101 atataaatag tgaagataga ggtttttttc tgcctgatat gggtacaaat ggattgttct
     2161 taataaataa aaaggcatat gaagtatatg atagtgtaga tttgcaatta gaattagcaa
     2221 agactatgga caagtatttt gaatcagatt ttatatactc attctgtgat gggattacat
     2281 tttgtgaaac tctgggttta gagacattaa gaccagatta tgattttcca agtgtattga
     2341 cacatactat aactgacaga gataaattaa gaaaattaga tgttccagac ccttatacga
     2401 gtggacgtat gccactcaat atagagagct tatcagttat atcaaaaagt attaaaaaac
     2461 cactatatga atcgatacaa ggtccattta cacttgcagg tcaattagct ggagctactc
     2521 aacttttaag atgtataata actgataaaa aatttgtaga agaattgttg gaatttacaa
     2581 ctgaattggt aagaagatat gctgtagctg caaataaagc aggagcaaaa tatatttcaa
     2641 tagcagagcc aacgtcagta accctaagta aagatagatt tgatgaatat atagtaaaaa
     2701 atttaaataa aatctacaat gaacttgatt gttggaaagg tatgcatata tgtggagaca
     2761 ccagagaatt attagataat atgctaagtt gtaatataga tgcagtaagt ttagaccaaa
     2821 ttttagacta tgaagaaatt gctccaatga ttcctagaga tatagtgttg attggtaatt
     2881 tagacccaat aaaacttctt ggacgttcta agccagataa gattagaaga gagacactaa
     2941 aattgttaaa gaagatgaga ggatatgata actttttatg tgattttggc tgtaactgct
     3001 taaataccac tccagtagaa aatttacaag cagctataaa agcaggaaga attaattata
     3061 aagaattaga taggattgat attgatgaat tataatagta ataaaaataa atatctttta
     3121 aaggatataa atttagagga tatttttata gataagaata ttgtgctaaa gtttttgggg
     3181 tatggaaata gaaaagctcc agatacaatt agtgaaatcg ttgaaagaga aataagaaat
     3241 ataaatgata ttttagatat caagatatat ataagtgaag ttgatattaa taaaacacct
     3301 aaagaatgta aaaaagcatt tgctgtacta tatacaatag gggataaaat tgatattaag
     3361 atgaatgact atatggaaaa ttgcaatatg atggcaggga tagcattgga taaaataggt
     3421 atagtatgtt tagattatat taatgagaaa ataaaaatgt atttaaaagg aaagtatgat
     3481 agtcttaaaa tatcgcatga aatatatcca ggagataaag attttgaagt agagagacaa
     3541 aaggatattt ataactatgt aaaaaataaa tataatagta tagaaataga aatcaatgat
     3601 tatcatcaac tatcccccat aaaaagtgtt gcaatgctta ttttaatggg agatgaagaa
     3661 aatttagaat caagatgtag caaatgtcct agaaaatgct tttaactagt tttcaagact
     3721 aagatttgtt ttgtgtatga attgcaataa tttttttggt cattttatgt ataaactaaa
     3781 aaaattattg caaagtaata ttctatttaa tttgaacaga cttacaaact atagtagttt
     3841 ctttaattca ataagtgtat ttatttcata agttggtata tgattagtat aatttatact
     3901 gttattggaa tttaaccaac aagtatctat tcctgaattt attccaccta agacatcaga
     3961 ggttaagcta ttcccaatca ttaaggcaga agatttatca tgacaattaa actttttgag
     4021 agcgtattta aatatttcag gatttggttt tgatattttc aactcttcag atacaaccat
     4081 tccatcaata tatcctttta tttttgaatt ttcaagtctt ttcttttgaa ctgcagaaat
     4141 tccatttgtt attataacaa tagtatactt ttttttaaga tattgtaata tatcgattgc
     4201 acctggaatt aaaaatgtac attcacctaa aaaatttaag tacattttgc taagagtttc
     4261 agaatcaaca tccaaagata ttttatttgc aaaaagttca aatctaagta atttaagttc
     4321 attcaaagtt ataatatttt tttcaaggtc gagccaaagc ttatcactta tatttctata
     4381 tgactctata taattctcaa aattaaattc taaatcaaac tcagatagaa gttttttaaa
     4441 agcatgtgat tcacttttct taaaatcaaa taaagtatca tctgcatcaa aaaatataaa
     4501 tttatatgtc ttcatggttt ttactccttt acaagatgac tgcaaaaatt actttacttt
     4561 cactatttga gtcattttgc catttatgct ttgttcctaa aggaactttt acactatctc
     4621 ctttggacaa agtaaattca tcatcatcca taaaaagttt aacttctccc tccaaaacat
     4681 atgcaatttc atctccatta tgagtaatcc tatcaataca agaagaagta tttggagcta
     4741 aatccataat tgcaaattct aaattaccac tagagtctgg aattaaaatc tcatatataa
     4801 cttctttgct tccaggtaaa ataacttttt ttctattatc atgtcttact atcaagtttt
     4861 ttttatctac ttcagataca aaaaatgtaa ataaaggaac gtttagagaa gaggctatag
     4921 attttaatga atttacagat ggattagcaa gacctcgttc tatttggctc aataatgatg
     4981 gtgtaacatc agctagtttt gctaaatctc gaatacttaa gttttgtttt tttcgaactt
     5041 cagctatttt ttcccctaaa tttaaatcat tcatataaat atcctctctt tttaatttaa
     5101 aaaatattaa cttaaaataa tcaagtaaaa tgattatgta gtatgaaatt attataacat
     5161 atagaattag gttttgaaaa aactatgttc aatataatta aataaattaa aatataattg
     5221 acaaagtgga tacagaatac ttaaaatata tttaaataaa attaagcaaa agatagttaa
     5281 tttatgatag gaggggacat tatgcaaata acgacttttg gagctatatt tggtttatta
     5341 atagcaatta ttttaattat aaaaaaattt caagctgtat atagtttaat gttaggagca
     5401 tttattggag gattagttgg aggagcaaat ataacacaaa ctgtagattt tatggcaaat
     5461 ggagctatga atatatcacc atcaattctt agagctttgg catcaggtgt attagctgga
     5521 agtttaataa aaacaggagc agtagataaa atatcagaac agattgtaaa aatatttggt
     5581 gaaaagaggg ctttattttc gattgccatt tcaactatgg tacttgctgg agtaggcgta
     5641 aatttggatg tatctataat aactgtagca cctataggat tatatatagg tagaaaatta
     5701 aattattcta aattgtcaat actattagct atgttgggag ggggtaaagc aggtaatata
     5761 atatcaccaa atccaaatac tatagcagta gcagataatt tttctgtcaa tctctctagt
     5821 gttatgatgg caaatataat tccagcaatt attggagttg ttattacagt tattttagca
     5881 agtatattaa taaataaagg aaataaagta caatcatatg aaattttaga gcaaagagaa
     5941 gatttaccaa gtttatttaa atcattatgt ggtccaatta tagctatatt tctattgttt
     6001 ttaggaaatg tatctcctat agttatagac ccaatgatag cccttccaat aggaggaatc
     6061 gtaactctaa ttgtcacagg aaacttgaac aattcaagag aatatttagc ttttggatta
     6121 tctaagatgc aaggggtatg catattatta cttggaacag ggactatcgc aggaattata
     6181 cagatgtctg aattacaaca gagtacaata ggtgctttac aatttttaaa tatgccacaa
     6241 tttttattgg caccagtttc gggtatactt atgtcattag caacagcatc atcaacagct
     6301 ggtgctacta tagcatcatc tacttttcat gatgctataa taaatggtgg gctatcaccg
     6361 atttcaggtg catcaatagt aaatgctggg tctagtgtat tcgagcaatt accacatggc
     6421 tcactatttc atactagttc aggtagtata aacatggata taggtgaaag atttaagtta
     6481 attccatatg aagcattgat aggaatagta atgactataa tttcaacatc tattcaatta
     6541 gttttataat aaatataaat atttaatgaa aaaagtagga ttttgttatt aaatattgaa
     6601 tttattatag taaaaaagaa gattggagtt ttaaagtgaa taaaaaaaag attgttatta
     6661 tagggattat ttattcattt ttagtagtat tttcacttac aaatatgtat gtaaatatgg
     6721 agtataattt aaatgtattt gaatatatta agaagtcact tccatttaca gaagaagaaa
     6781 aaaagtggtt agaaaaacac aagaatttga tttacagctc tgaccaaagt tcacctcctt
     6841 tgagatataa gggtaaggaa gatggacagt ataagggaat tattgttgat ttaataaatt
     6901 ctctgtcaat tcaaattggt agagattttt attttaaacc aaataattgg tggaaagaat
     6961 ctttcgtaaa ttcaatagat gatagtataa agttttttga cttgattcca tcaaaagaaa
     7021 gggcaaataa atttatattt actgacccaa tatacacttt gagtgcaaat atattgaaag
     7081 ataaaaagtc ccaagatata aatagttaca tggatttaaa ggggaaaaca gtagcaattc
     7141 cagaaggtga ttattctata aattttttaa agcaaaaaat tcaagatata aacattttat
     7201 tgactccaga tataaagact ggagtcaacc atttaatgtc tggaaaagta gacgcagttg
     7261 ttggtgatga accagtattg cgatactata taaataatta tggactttca aataaataca
     7321 gtgttttaag taatcctata tatactaaaa aagcagttct tgctgtacct aaacaatatg
     7381 aagagctggt tagtatttta aataaaggca tttttaaact tcagaaaaat ggagtgtata
     7441 aagatttaaa gaaaaaatgg tattctacgt ataatgaagt tgatgatata ttgtatgagc
     7501 gaggaattgt gcctagtatt tatcttttta taggtataat tttaatatca atttatgttt
     7561 tttatagcta tacatatttg ttaaagatag aaatcaaaag gaaaacagaa caggtaatag
     7621 aaaataaaaa aactttagag gcaactttta atagtattac agatataata atgcttgtag
     7681 atgaaaataa caatatagta gaatcgaaca aagtactata tgactttatg ggtgaaatga
     7741 gttataagat agcagatttg attagcatga taaaaggtgt tattaaaaat accttctctg
     7801 aaaatactaa taaaactagt gaaatagaaa tatacaataa aattttaaag ataaacactt
     7861 ttcctgtaga gtataaaaaa aataatactg agtatatagt agttcttatt aaagatataa
     7921 ctaatgaaaa aatagtagag gcgaaattac ttagagaaaa caaaatgata tctataggac
     7981 aattagcttc tggggtagca catgagataa gaaatccttt gggtataata agaaataatt
     8041 gctatctatt aaaagataac gttacaatgg aagaagtgaa tgattgtgtt aaatcaatag
     8101 aaagtaatgt agatagggca agtaatataa taaccaactt gttaaatttc gcaagaatat
     8161 cagatgataa tttagaacat ataaatataa gaaattttat tgaaaatata gtgaaacttc
     8221 aatataaaat gttacagtta aagaatgttg aaataaaaat tgactgtgaa cataatttag
     8281 tatgctatat aaatggagaa tcgttaaaac atgtatttat aaatttaatt tctaattcaa
     8341 tagatgcaat acatcaagat ggaaaaatta ttatatactg ttatgaaaaa aatcattgtt
     8401 tatttataga ttttaaagat aatggtgaag gaataaaaga agatgcccta aaggacatat
     8461 ttaatccctt ctatacaaca aaaccaattg gtgagggaac tggtttaggt ttatatatta
     8521 cttataatga gattaaaaag aataatggag atataagtgt tgaaagtaaa ttgggggttg
     8581 gaacttgttt tcatataaaa attccattaa ataaagaggt gactatataa tgaaaatact
     8641 attagttgat gatgagctag aatatggagt ggtaatgaaa aaaattctac aaaagaaggg
     8701 ctatcttgta gatatagcac taagtggtga agaagctata aatataatta aaaaagataa
     8761 aaattatgat ttggttttat ctgatgttat gatgaaaaat atggatggag tacagctatt
     8821 agatagaatt aaatctatta atagagatat agaggttata ttagttacag gatatggaag
     8881 tattgaaaat gcagttgatg ctatgaaaag aggagcttta tcttatttta taaaaagtaa
     8941 tcccattgaa aatttattag aagaagttga aaaggtaaag gcaagtaaaa tatctgtttc
     9001 tgtacaaaaa aataattttg aatttacttt ggaatctaaa aatagagatt ttaataatat
     9061 cataaaaata gcaaaaaaag ctgcttgtaa agatgttaat atattaatct tgggggaatc
     9121 tggtgtagga aaagatatat tagctagata tatacatagt ataagtccaa gaaagaatga
     9181 gatatttgta cctgtaaatt gttgttcttt ttcagaaaat ctattggagt ctgagttgtt
     9241 tggtcatgaa aaaggttctt ttacaggagc agtagatagt agaaaaggta gatttgaact
     9301 ttcgaataaa ggaactctat ttttggatga aataggagat atacctctaa atgttcaggt
     9361 aaaacttttg aggacacttg aggacaaatc tatagagagg ataggaagta ataaatctat
     9421 taaagttgac tttaggttaa tttgtgctat gaataaagaa ccaaaagtgg aaatatcaaa
     9481 tggaaatata agagaagatt ttttttatag aataagtaca ataacaataa ctataccacc
     9541 actaagaaag agaagagaag acttaactac tcttatagaa tttttcttaa ataagtacca
     9601 aattgaacat gataaaaaga tacactcgat tgataaggaa gtaaaggatt ttttattaaa
     9661 ttacaattat ccaggaaata taagagaatt aaaaaatata ataaatagac ttgtagtttt
     9721 aagtgaagaa ggcaatttat caaaagacaa tttaaattta atatcaaata atgtatacat
     9781 agatgataaa ataagtatta gacctttaag agaaataaga aaagagtttg aatgtgagta
     9841 tattgaaaaa gttttatctt tgtgtggaaa taatatttca aatacagcta aaaaattgga
     9901 gattagtaga agacagttaa ccaataaaat atcagagtat aatattaagt gagaaaaaaa
     9961 cttctcatta agtgagaaaa aaatttctca aactgtatta aaagataaag agaaaaaatc
    10021 tgtttatctt tttttattat aattttaaaa attaatattt acaataatta ttggtaaatt
    10081 caatactggt gtaaattaaa aatgaaaatt tctatgacat taatacatag aatatatatt
    10141 ttaaataatt ggcatagaaa atgctttata tattaataaa cgtaataaat atttttaatt
    10201 gcgattaaat atattaaggg ggattttcat atgaagctag agctagggaa tatatttata
    10261 aaaaatgttg aatttggaga aaagacagaa gtaaaagatg gagtactata tattagtagc
    10321 gaagaaatag aaaagatagt attagaagat gaaaggattg taagtgtaaa tgttgaactt
    10381 gcaagacctg gcgaatcaat aagaatagct ccagttaaag atgtaataga gcctagagtt
    10441 aaaattggag atgaaagcaa aatatttcct ggaattataa ataaagtgaa gactgtagga
    10501 agtggaagaa cccatgtact tttaggagct tgtgttgtaa cttgtggaaa tatagttgga
    10561 tttcaagaag gcgtaattga tatgagtggt cctactgcta aatatacacc tttttcaaaa
    10621 acaaataata tatgtattgt tataaaagca aaggatggta tagatactca tgattatgaa
    10681 gaagcagcta gaattgcagg attaaaaata ggtgcatatg taggtgaggc aggaagagaa
    10741 gttgagccag atgaagtcat tgtatatgag acaaagccat tattaaaaca agtaaaagaa
    10801 tatccagacc tgccaacagt agcatatgtt cacatgttac aatcacaagg acttttacat
    10861 gacacttatt actatggggt ggatgctaaa cagatagtgc ctacatttat gtatccaact
    10921 gaaataatgg atggagctat aatatctgga aactgtgtag caccatgtga taaggttaca
    10981 acattccatc atttaaataa tccagttata catgacttat ataaaagaca tggaaaagat
    11041 ttaaacttta taggagttat tttgactaat gagaacgtat tcttagtcga taaagagaga
    11101 agctctgata tggtagctaa attaatagaa tttttaggag ttgatggagt tctagtgaca
    11161 gaagaaggtt atgggaatcc agatactgac ctaatgatga attgtagaaa atgtagtgaa
    11221 gttggagcaa atgtagtttt gataacggat gaatttcctg gaaaagatgg caagagtcaa
    11281 tctatagcag acgctactaa ggaagcagat gcagttgttt cttgtggtca aggaaatcta
    11341 gtggttcatt tcccagcaat ggaaaaaatt ataggaactt tagattatgt tgaaatgatg
    11401 ataggtgggt ataaaggatg cttaaatgaa gacggaagca tggatgcaga gctacaaatt
    11461 ataatagcat caactatagc aaatggctat aatcatttga cagcaagata ttattaaata
    11521 agtatttgaa tataaagttc tgttgatgta atcgttggtc taattgatgt aataactata
    11581 aagtgatttg gaggattaag agatgagtaa aatcagagtg gttcattata taaacaattt
    11641 ctttgctggt ataggtggag aggaaaaagc agatattccg ccagaaaaaa gggctggtgt
    11701 agtaggacct ggaatagcat ttcagagtca atttaatgat gatgcagaga taatctcaac
    11761 tgtaatttgt ggagatacgt attttggtga aaatattgag agtgcaactc aagaactttt
    11821 aaaaatgata aaagaagaaa gccccgattt atttattgca ggcccagcat ttaatgcagg
    11881 tagatatgga gtagcttgtg ggactatttg taaggcagtt gaagaagagt taaatattcc
    11941 tgtagttaca ggaatgtata aagaaaatcc aggtgtagat atgtttaaat tagatttgca
    12001 tatagtgtct acaggaaatt cagcagcaag tcttagaaag gtagttccaa taatgacgaa
    12061 actaggtctt aaattggtta gaggtgagga aataggacct cctgaagagg aaggatatat
    12121 aatgagagga ataagaaaaa atttcttcca tgaacttaga gggtctgaaa gagcaattga
    12181 tatgttggtt aaaaagatga aaggggaaag ctttgaaact gagtatccaa tgcctgaatt
    12241 tgatagagtt acacctatga aacctgttaa agatttatct aagataaaac ttgccctagt
    12301 aacttctgga gggatagttc caattgataa tccagacaaa attgaatctt caagtgctac
    12361 taaatatgga atttacgatt taacagatat ggattctatg tcaaataaag aatttacaac
    12421 tatacatggg gggtatgaca gagcatatgt ccttgaaaat ccaaatttag ttgtaccatt
    12481 agatgtagtt agagagcttg aaaaagaagg tgtaattgga gaattagtag attattttat
    12541 aactactaca ggaacaggaa cgagtgttgg caattctaag agatttggag aagagttttc
    12601 taagaaattg ttagaagatg atgtagatgc tgtaatttta acttctacat gaggtacttg
    12661 tactcgttgt ggagcaacga tggtaaaaga gattgagaga gctggtatag cagttgttca
    12721 tatatgtaca gtagtaccaa tatcacttac aataggagct aatagaattg ttccagcagt
    12781 agggatacca tatccacttg gaaatcctat gttaggagaa gaggaaagta aaaaaattag
    12841 aaagaatata gttttaaaag ctttaaatgc actaacagag gatatagaag aacaaacagt
    12901 atttgaataa taaaaatata atatagaaat aaaaaaagat atcataaaat agtttttgaa
    12961 aattatttta tgatatcttt ttgctatgga tggaatgaag aaagcaatta agtaataaaa
    13021 at
//
LOCUS       DAMJYN010000095        12987 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.099, whole genome shotgun sequence.
ACCESSION   DAMJYN010000095 DAMJYN010000000
VERSION     DAMJYN010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12987)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12987)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12987
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.099"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(<1..1183)
                     /locus_tag="PC466_003092"
     CDS             complement(<1..1183)
                     /locus_tag="PC466_003092"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000469013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HDF2770453.1"
                     /translation="MFNTIEEAIEDIKNGKMVIVVDDESRENEGDLLMAAEMATPESI
                     NFMATYGRGLICLPATEKKFKSLNIPLMVRENTDTFQTAFTVTIDGADTLTGISAYER
                     AETVKLFCDENSTSKDFKTPGHIFPLIAKTGGVLVRDGHTEASVDLARLAGFKEIGLI
                     CEIMKDDGTMARVDDLMIFKEKHNLKIITIKDLIEYRKINETTIEKVSSAFLPTKYGN
                     FEIIGYRDTYSNEEHIALTYGNINIENTLVRLHSECLTGDVFHSLKCDCGLQLESSMK
                     KIVENGSGVLIYMKQEGRGIGLLNKIKAYKLQEEGYDTVEANLMLGFEEDMRDFYMAA
                     QILKNLNIKSINLLSNNPDKINQLEKYGIKIENRIPINEEINDFNKLYLKTKKDKMGH
                     LL"
     gene            complement(1206..1871)
                     /locus_tag="PC466_003093"
     CDS             complement(1206..1871)
                     /locus_tag="PC466_003093"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HDF2770454.1"
                     /translation="MFTGIVEEVGILRKITANGKSGKVTILSNKILDGTNLGDSIAVN
                     GVCLTVSNLGKNEFTADVMMETIRSTNLGLLNANDKVNLERAMSLSSRFGGHIVTGHV
                     DGKGTICKFEKDENAVLVSIRPDKKLLSSMILKGSVAIDGVSLTISYLDDEIFKVSII
                     PHTKINTILLTKNVGDFVNLESDVIGKYVNNFMANNYKELNSNSSNHKSNIDKDFLFK
                     NGF"
     gene            complement(1905..3008)
                     /gene="ribD"
                     /locus_tag="PC466_003094"
     CDS             complement(1905..3008)
                     /gene="ribD"
                     /locus_tag="PC466_003094"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HDF2770455.1"
                     /translation="MNQKEKDIYYMKKAIELAKNGEGFVNPNPLVGCVIVKDSNIIGK
                     GYHEKFGSNHAEVNAINSAKQSLKDSTLYVNLEPCSHYGKTPPCVDKIIQNKIKRVVI
                     STLDPNPLVCGNGVKKLKDNNIDVTVGILEDEARDLNEAFFYHIKNKRPLCIVKSAVS
                     LDGKIATKSLESKWISNESSRYLTHKYRNKYQSIMVGINTVLNDNPLLTCRLNQEKVS
                     HPTRIVIDTHLKLPLNSNLVKDKTSKTIVFTCCKESIKLSMLKENNVETIISPSKNNL
                     VDLEFVMYKLGELNIDSVLVEGGATLNDSLFRNKLVDKVKLFLSPKIIGGKDAPTFVS
                     GEGINHLSDSTQLTINNVTLIDGDILIESDVLN"
     regulatory      complement(3140..3261)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            3450..5933
                     /gene="recQ"
                     /locus_tag="PC466_003095"
     CDS             3450..5933
                     /gene="recQ"
                     /locus_tag="PC466_003095"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HDF2770456.1"
                     /translation="MNKKLLEILSKYYGYTSFRKGQESIINSILSEKDVLAIMPTGGG
                     KSICYQIPALILDGMTIVISPLISLMKDQVDALKTMGISAAFINSSLSSKEFNEILNN
                     IRKNNYKILYIAPERLDAQEFIELINNNNVSQVAIDEAHCVSQWGHDFRLSYRRISDF
                     IKNLPKRPIVTAFTATASEEVRTDIINLLCLENPDYYITGFDRENLSINIVKSSSKNK
                     YILDYIQNHKNESGIIYVATRKEVENIYNGLSKRNISVSKYHAGLSKNERSKNQEDFI
                     NDNVDIMVATNAFGMGIDKPNIRWVIHYNMPQSIENYYQEIGRAGRDGEKSECVLLFS
                     PGDVHIQKYLIDIGVENPERKLFQHKKLQYMIDLVYSNSCYRKTILSYFGENYIDNCN
                     NCSNCLVEGEIVDKTIDAQKVISCVARMKRSYGVTTIVDVLRGSKNKKILQLGLNTLS
                     TYNIMRDYSSEDLKNFVNTLVSHGFLDLVETLGNGNRGSFPTIRLNEMSMKVLKGEVK
                     VEFKEIVMTKSLEVEDELYNALRELRHSIASEERIAPYMVFGDGTLRAMSSSYPINKE
                     EMLDISGVGEIKYQKYGRDFEAVIKEYVEKNNINKKIDEKNVDLKNVNSDFLEVNTDK
                     VLYEKLLVIREEYATKEKLPAYMILANKALKEISGRYPLDEEQLKDISGIGGVKFEKY
                     GANILAEVNKYVKENNINVIWEKKGKRKLILDGESRKNNEIALDLLNQGKDIQSISQE
                     IEVSLSTIIGYVHDYVKDGHSISFELGLENFYNEDKKKMILEVCEKVGYDNLNNIKRK
                     LPDSIKYENIRAVMLDSYLENLKNNIIAE"
     regulatory      6021..6132
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            6274..7575
                     /gene="thiC"
                     /locus_tag="PC466_003096"
     CDS             6274..7575
                     /gene="thiC"
                     /locus_tag="PC466_003096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomethylpyrimidine synthase ThiC"
                     /protein_id="HDF2770457.1"
                     /translation="MNYTTQMDAARKGIITKEMEIVSQKEQVDVNELRELIANGQVVI
                     PANKNHKSLSAEGVGKNLRTKINVNLGISRDCKDIEKELEKVRVAIDMKAEAIMDLSN
                     YGKTREFREKVVEMSPAMIGSVPMYDAVGYLEKELKDITEEEFLNVIRQHAIDGVDFI
                     TIHAGLTRSVCQKIKNHERLTHIVSRGGSLLFAWMELNNKENPIYTNFDKILDICEEY
                     DVTLSLGDACRPGCIKDSTDGVQIQELVVLGELTKRAWERNVQVMIEGPGHMAIDEIE
                     ANVVLEKRLCHGAPFYVLGPLVTDIAPGYDHITSAIGGALACAKGVDFLCYVTPAEHL
                     RLPNLDDMKEGIIAAKIAAHAGDIAKNVKGAREWDNKMSKARADLDWCEMFRLAIDPE
                     KAKRYRDESTPTHEDSCTMCGKMCSMRTVKKILNNEELNLI"
     gene            7629..7823
                     /gene="thiS"
                     /locus_tag="PC466_003097"
     CDS             7629..7823
                     /gene="thiS"
                     /locus_tag="PC466_003097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfur carrier protein ThiS"
                     /protein_id="HDF2770458.1"
                     /translation="MKVNGKEIEFEKDLTVIDLLNKYNLKSDRVVVEVNLEIIEESNY
                     NTYVLKDEDIVELISFIGGG"
     gene            7816..8619
                     /gene="thiF"
                     /locus_tag="PC466_003098"
     CDS             7816..8619
                     /gene="thiF"
                     /locus_tag="PC466_003098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine biosynthesis protein ThiF"
                     /protein_id="HDF2770459.1"
                     /translation="MVKIKIFVNELLTDVEENTTAYKVRDSYNNKCDVLVLNGYPIKT
                     DMPLCENDKLTLIQKGVKPSLDELESLLIARHTPNIHNKLKKGKVAILGLGGLGSNIA
                     ISLARIGVGELLLIDYDVVEPSNLNRQQYFIDDIGKLKTDAMIENIKKINPFIKLNKR
                     DIFLNKNNMDTIKDSDLIIEAFDDASCKAQVCNYVLINLKDKYLIASSGMAGYYDSNI
                     ITTKKIKDRFYICGDFVNEAKFGEGLMAPRVAICANHMANLATQILIDM"
     gene            8682..9452
                     /locus_tag="PC466_003099"
     CDS             8682..9452
                     /locus_tag="PC466_003099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018592874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiazole synthase"
                     /protein_id="HDF2770460.1"
                     /translation="MDKLVLGGHEFNSRLLVGTGKYGSNNILPEVIKESGSEIITMAL
                     RRVDLDNKQENILTYIPKEMTILPNTSGATNAEEAVRIARISRKMGCGDFIKIEVISD
                     TRYLLPDNEETIKATKILADEGFIVLPYMTPDLYAGRRLIEANAAAVMPLGAPIGSNR
                     GLQMKEMIRIMIDELDIPIIVDAGIGKPSQAMEAMEMGADAVLVNTAIASAGDPVQMA
                     RAFKLAVEGGREAYIAKTGNVSEFANASSPLTGFLGNL"
     gene            9469..10572
                     /gene="thiH"
                     /locus_tag="PC466_003100"
     CDS             9469..10572
                     /gene="thiH"
                     /locus_tag="PC466_003100"
                     /EC_number="4.1.99.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-iminoacetate synthase ThiH"
                     /protein_id="HDF2770461.1"
                     /translation="MSFYDVIEKYRDFDFDGYLNNVTDNDVLRSLSKDKLEDFDILNL
                     LSKTAVKHLEDMAQKAHKLSVQYFGKTVCLYTPMYIANYCVNQCVYCSYNIKSGIKRK
                     KLTMDEIREEGEAISKEGFKHLLVLTGESSFHSSVEYIGEAIEILREKFPSIGIEVYP
                     MEVEEYKYIVDKGVEGLTVYQETYDEEIYKRVHIKGPKSNYEFRLDAPERGAKAGMRT
                     LSIGALLGLNDFRKETFFTILHGKYLKTKYPHIELSYSTPRMRPFKGCFEELVDISDT
                     DLVQAMVCMRLFDPHAAINISTRENLEMRSHIIPLGVTKLSAGVSTDVGGHSQDEHDT
                     AQFKINDESTVKDVEKMLNSIGYQHVFKDWERF"
     gene            10573..11262
                     /locus_tag="PC466_003101"
     CDS             10573..11262
                     /locus_tag="PC466_003101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HDF2770462.1"
                     /translation="MYLITNRKLCSEERYLEVIKESILSGVENIIIREKDLEYQELRK
                     LYMKIKTKINCIDFQEQISDESLKTNINQKECRNKFKVNFIINSNIEFFEKVDCQGIH
                     LPFKLFLNLIENKYNFNENKILGLSLHKVEEVDYLEKLIRNQNIKIDYITLSHIYETK
                     CKEGLNPKGIELLKEAKKITDIKIIALGGILPSNVKETLKYCDDFAIMSTIMRSKDIK
                     KTISNYNEKLN"
     gene            11450..12844
                     /gene="yfcC"
                     /locus_tag="PC466_003102"
     CDS             11450..12844
                     /gene="yfcC"
                     /locus_tag="PC466_003102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HDF2770463.1"
                     /translation="MTDSKKKRFIIPHTFTIIFLLIVLMAILTWIVPSGEFSREDVEG
                     RMVVVPGTYQSVESNPQGFADVFKAPIEGFIDSAEVVGFVLIVGGAFGIVNRTGAIEA
                     GIASVISKFKGKELLIIPISMILFGLGGTTFGMAEETLPFYMIFVPLMTSLGYDSLTA
                     IAIVFIGAAAGAAASTINPFSVGIAQALAQLAPGSGVTYRVVIFIAYILISIAFVMYY
                     AKKVKENPESSIVYEIDKNNKSILNQTSTEIKEFTFKEVSVLAIFGIGMAIMIWGVLS
                     QGWYIPEISMCFAAIGVLSGLVGRLSQIEISESFIDGAKDLASAALAIALARGIVIIA
                     QNGFIIDTILNSAAAFLGGLPKVIFVYLSFFLEAALAFLIPSSSGLASLTVPVLAPLG
                     DLVNISAQVIVTAYQFGVGLTNFITPTSGVLMGALAVAHIPFSKWVRFIMPILLILTA
                     VSLVFLTIGIYIGF"
BASE COUNT         4876 a         1556 c         2215 g         4340 t
ORIGIN      
        1 ctaaaagatg tcccatttta tcttttttag tttttaaata tagcttatta aagtcattaa
       61 tttcttcatt aatagggatt ctattttcga tttttattcc atatttctct aattgattta
      121 ttttatccgg gttattactt aaaagattta tactttttat gtttaaattt tttaatattt
      181 gagcagccat atagaaatct ctcatatctt cttcaaatcc aagcattaaa tttgcttcaa
      241 cagtatcgta accttcttct tgaagtttat aagccttaat tttatttaaa aggccaatac
      301 ctctaccttc ttgcttcata taaattaaaa ctccacttcc attttccaca attttcttca
      361 tagaagattc tagctgtaat ccacaatcac attttagaga gtggaacaca tctcctgtta
      421 aacattcaga atgaagtcta actagagtat tttctatatt tatatttcca taagtaaggg
      481 caatgtgttc ttcatttgaa taagtatctc tatatcctat gatttcaaaa tttccatatt
      541 ttgttggaag gaaagcacta gatacttttt ctatagtagt ttcatttatt ttgcggtatt
      601 ctataaggtc ttttatagtg atgattttta aattatgctt ttctttgaaa atcattaaat
      661 catcaactct tgccattgta ccatcatctt tcattatttc acagataaga ccaatctctt
      721 taaaacctgc aagtctagca aggtctactg aggcttctgt atgtccatcc ctgacaagaa
      781 ctccaccagt ttttgctatt aaaggaaata tgtgaccagg cgttttgaaa tctttacttg
      841 tagaattttc atcacagaac aattttacag tttcagctct ttcatatgca gatataccag
      901 ttagagtatc tgctccatct atagtaacag taaaggctgt ttgaaatgta tctgtatttt
      961 ctctaaccat aagaggtata ttaagacttt taaatttttt ttcagtggca ggtagacaaa
     1021 ttagacctct accatatgta gccataaaat ttattgattc aggagtagcc atttcagctg
     1081 ccatcaataa atctccttca ttctctctac tttcatcatc aactacgatt accattttcc
     1141 cattttttat atcttcaata gcttcttcaa tagtattaaa catgtaattc actcctttat
     1201 tatttttaaa aaccattttt aaataaaaaa tctttatcta tatttgattt atggttacta
     1261 ctattagaat ttaattcctt gtagttatta gccataaaat tattaacata ctttccaatt
     1321 acatcgcttt ctaaattaac aaaatctcca acattctttg tcaagagaat agtgttaatt
     1381 ttagtatgag gtataataga aaccttaaat atttcatcat ctaaatatga tatagttaaa
     1441 cttacaccat caatagcaac agaacctttg agtatcattg aagataaaag ttttttatca
     1501 ggtcgtatac ttactaaaac tgcattttca tctttttcaa atttgcagat agttccttta
     1561 ccatcaacat gacctgttac tatatgacca ccaaatcttg aagaaagact catagctctt
     1621 tcaagattta ccttatcatt tgcatttaat aaacctaaat ttgtggaacg aattgtctcc
     1681 atcataacat cggctgtaaa ttcatttttt ccgaggtttg aaacagttag acaaactcca
     1741 tttacggcta tactatctcc aagatttgtg ccatctaata ttttatttga tagtatggtt
     1801 acttttccac tcttaccatt agcagtaatt tttctaagta ttccaacttc ttctactatg
     1861 ccagtaaaca tcctaacctc ctatatgaat gtattaacaa aaatttaatt taaaacatct
     1921 gattctataa gaatatcgcc atctatcaaa gttacattat tgattgttaa ctgtgttgaa
     1981 tctgacaaat gatttattcc ttctccagaa acgaatgtag gtgcatcttt accacctata
     2041 atcttgggtg atagaaataa tttgacttta tcaactaact tatttctaaa gagactgtca
     2101 ttgagagtag caccaccttc aactagaaca gaatcaatgt ttaactctcc taatttatac
     2161 attacaaatt ccaaatctac taagttgttt tttgaaggag aaattattgt ttcaacatta
     2221 ttttctttta acatagataa ttttatactt tctttgcaac atgtgaaaac tatagtttta
     2281 ctggttttat ctttaaccaa attactatta agtggcaact ttaggtgtgt atctattact
     2341 attcttgtag gatgagacac tttttcttga ttgagcctgc aagttagtaa aggattatcg
     2401 ttcaaaactg tatttatgcc aaccattata ctttggtatt tatttctgta tttatgagtt
     2461 agataccttg atgattcatt agatatccat tttgattcta gtgattttgt agcaatttta
     2521 ccatctagac ttactgctga ttttacaata caaagaggtc ttttgttttt tatatgataa
     2581 aaaaatgcct catttaaatc tcttgcttca tcttctaata ttcccacagt aacatcaata
     2641 ttgttatctt ttaatttttt tactccatta ccacaaacaa gtggatttgg gtctaatgta
     2701 gatattacaa ctctcttaat cttattttgt ataattttat ctacacaagg aggcgttttc
     2761 ccataatgag aacatggttc taagtttaca taaagagtag agtcttttag actttgttta
     2821 gcactgttta tagcatttac ttcagcatga ttagagccaa atttctcatg atatcctttg
     2881 cctattatat tactatcttt aacaattaca cacccaacta atggatttgg atttacaaag
     2941 ccttctccat ttttagccaa ttcaatagct tttttcatat aataaatatc tttttctttt
     3001 tgattcacaa tatgtacacc tcctgtttaa ttggataatt tttaaacaaa aaaccctgag
     3061 aattaactca gggtttagaa taatctacaa taaatgttta ataaaagtag aagaaaattg
     3121 ctctacaaaa acactcatta aatatcttct tccatccaga ctttactgtc ggctttggaa
     3181 tttaaccaaa tcaaccaagt tttaccttgg ctcgcgggct ataccgccga ttgggaattt
     3241 caccctaccc cgaagattaa gtattaaatt tatatttaga atgtatcata aattatttta
     3301 ctttgcaaac tattttttta aaaaatatat gttaatatat aatatagaat gtctataaac
     3361 tttgaaatac cacgattgtg aatataaaaa taaaaatttg aacataatca ggaaagaagt
     3421 ctaattaatt taaattagga gagtaatata tgaataaaaa acttttagaa atactatcaa
     3481 aatactatgg atatacaagt tttagaaaag gtcaggaatc tataataaat tctatcttaa
     3541 gcgaaaaaga tgtgttagct attatgccaa caggaggggg gaaatcaata tgttatcaaa
     3601 ttccagcttt gattttagat ggaatgacaa tagtaatttc tccacttata tcacttatga
     3661 aagaccaagt agatgcctta aagactatgg gaattagtgc tgcttttata aatagttcat
     3721 taagcagcaa agaatttaat gaaatattaa ataatattag aaaaaataat tataaaatac
     3781 tctatattgc tccagagaga ttagatgcac aagagtttat tgagctaata aataataaca
     3841 atgtaagtca agttgcgata gatgaagcac attgtgtatc tcaatggggg catgatttta
     3901 ggttgagtta tagaaggatt tctgatttta taaaaaattt gcctaaaaga cctatagtta
     3961 cagcatttac tgcaacagct tcagaagagg taagaactga tataataaat ttactgtgtt
     4021 tagaaaatcc agattattat ataactggat ttgatagaga gaatttatca ataaatatag
     4081 taaaatcatc tagtaaaaat aagtatattt tagattatat tcaaaatcat aaaaatgagt
     4141 ctggaattat atatgttgca actagaaagg aagttgaaaa tatatataat ggtttatcta
     4201 agagaaatat atctgtatca aaatatcatg caggtttatc taaaaatgaa agaagtaaaa
     4261 atcaagaaga ttttataaat gataatgtgg atataatggt agcaacaaat gcatttggaa
     4321 tgggtattga taaacctaat ataagatggg ttatacatta caatatgcct caaagtatag
     4381 aaaactacta tcaagaaata ggtagagctg gtagggatgg agaaaaaagt gagtgtgtac
     4441 ttttattttc tccaggagat gtacatatac aaaaatattt aattgatatt ggagttgaaa
     4501 atcctgaaag aaaattattt cagcataaga agcttcaata catgattgac ttagtttaca
     4561 gtaattcatg ctatagaaag acaatattga gttattttgg agaaaattat atagacaatt
     4621 gcaataattg tagcaattgt ttagtagagg gtgaaatagt agataaaact atagatgcac
     4681 aaaaagtcat ttcatgtgta gctagaatga aaagaagtta tggtgttact actattgtag
     4741 atgtacttag aggttctaag aataaaaaga ttttacagct tggattaaat actttgtcta
     4801 catataacat tatgagagat tattctagtg aagacttaaa gaattttgta aatacattgg
     4861 tttctcatgg ttttttagat ttagttgaga ctctaggcaa tggaaataga ggtagttttc
     4921 ctactataag attaaatgag atgtctatga aagttttaaa aggtgaagtg aaagtagagt
     4981 ttaaagaaat tgttatgaca aaatcattgg aagtagagga tgagttatat aatgctttaa
     5041 gagaacttag acattcaatt gcaagtgaag aaaggatagc tccatatatg gtatttggag
     5101 atggtacact tagagccatg tctagtagtt atccaattaa taaagaagaa atgctagata
     5161 tctctggagt aggagaaatt aaatatcaaa aatatggtag agattttgaa gcagtaatta
     5221 aagaatatgt cgaaaaaaat aatataaata aaaaaataga tgaaaaaaat gtcgatttaa
     5281 agaacgttaa tagtgatttc ttagaggtta atacagataa agttttatat gaaaaactgt
     5341 tagtcattag agaagaatat gcaacaaagg aaaaattacc tgcatatatg attttagcca
     5401 ataaggcttt gaaagaaata agtggaagat atccacttga tgaagaacaa ttaaaagata
     5461 tttctggcat aggtggagta aaatttgaaa aatatggagc taatattttg gcagaggtta
     5521 ataaatatgt aaaagaaaat aatattaatg ttatttggga gaaaaagggc aaaaggaagt
     5581 taatattaga tggagaaagt agaaaaaata atgaaatagc attagatttg ctaaatcaag
     5641 gaaaagatat acaaagtatc agtcaagaaa tagaagtttc attgtcaacc attattggat
     5701 atgtgcatga ctatgtaaag gatggacata gtatatcatt tgaattagga ctagaaaatt
     5761 tttataatga agataaaaag aagatgattt tagaagtttg cgaaaaagtt ggctatgata
     5821 atttaaataa cataaaaaga aaacttccag attcaataaa gtatgaaaat ataagagctg
     5881 tgatgcttga ctcttatctt gaaaacttaa aaaataatat tatagcagag taatttttaa
     5941 cttaataaaa ataaaatttg tattattgtg ttgaactaat aattttgctg tgttatactg
     6001 aatttgtaaa aataatgaaa aattagagct aggggcgcta gaattggcta gctgagagat
     6061 aaagccgtaa cttacaaacc ctaataacct gatcaagata atgcttgcga agggaagctt
     6121 tttaatataa ttttattata taaataggca aattattcaa tgttaggaga aatttgtcta
     6181 agtgtatata cgattataag agtgctttcc aaacgaggaa aagcactttt tttattttca
     6241 aaaactataa ctttaatctt ggaggattgt aatatgaact atacaacaca aatggatgct
     6301 gctagaaaag gcataataac taaagaaatg gaaatcgttt ctcaaaaaga acaggtagat
     6361 gtaaatgaat taagagaatt aatagcaaat ggacaagttg ttataccagc taataaaaat
     6421 cataaatctt taagtgcaga aggtgtaggt aaaaatttaa gaacaaaaat aaatgtaaat
     6481 ctaggaattt caagagattg taaggatata gaaaaagaac ttgaaaaagt tagagtagca
     6541 atagacatga aagctgaagc tataatggat ttaagtaatt atggcaaaac tagagaattt
     6601 agagaaaagg ttgttgaaat gtcacctgca atgataggtt cagtacctat gtatgatgca
     6661 gtaggatatt tggaaaaaga attaaaagat ataacagaag aagagttttt aaatgtaata
     6721 agacaacatg ctattgatgg agtagacttt attactatac atgcaggtct tacaagaagt
     6781 gtttgccaaa aaataaaaaa tcatgagaga ttgactcata tagtatctcg tggaggttct
     6841 ttattgtttg catggatgga attaaataat aaggaaaatc ctatttatac taattttgat
     6901 aaaatattgg atatatgtga agaatatgat gttacattga gtttaggaga tgcttgtaga
     6961 ccaggttgta taaaagattc tactgatggt gttcaaattc aagaacttgt agtattaggt
     7021 gaacttacta aaagagcatg ggaaagaaat gtacaagtaa tgatagaagg tcctggacac
     7081 atggctattg atgaaataga agcaaatgta gtattagaaa agagattatg ccatggagca
     7141 cctttttatg ttcttggacc attggttaca gatatagcac caggttatga ccatataaca
     7201 agtgcaatag gaggagcttt agcatgtgct aaaggagtag attttttatg ttatgtaact
     7261 ccagcagaac atttaagatt gcctaattta gatgatatga aagagggtat aatagctgca
     7321 aagatagctg ctcatgcagg agatatagct aaaaatgtta aaggtgctcg tgaatgggat
     7381 aataagatga gtaaagctag agctgattta gactggtgtg agatgtttag acttgcaata
     7441 gaccctgaaa aagctaagag atacagagat gaatcaactc ctactcatga ggatagttgt
     7501 actatgtgtg gaaaaatgtg ctcaatgaga acagttaaga aaatattaaa caatgaggaa
     7561 cttaatctaa tataattttt ggctagtatg actggaataa aaagaagctg aaaagaggag
     7621 gtgatttagt gaaggttaat gggaaggaaa ttgaatttga aaaagatttg actgttatag
     7681 atttattaaa taaatataat ttaaaaagtg atagagttgt agttgaagtg aatttagaga
     7741 taattgaaga atctaactac aatacatatg tattaaaaga cgaggacatt gtagagctta
     7801 ttagctttat tggaggtggt taaaataaaa atatttgtaa atgaattatt aacagatgtt
     7861 gaggaaaata caactgctta taaagttaga gatagctata acaataaatg tgatgtattg
     7921 gtgttaaatg gatatccaat taaaacagat atgccccttt gtgaaaatga taaattaaca
     7981 cttatacaaa aaggagttaa gccatcactt gatgaattgg aaagcttgtt gattgctaga
     8041 catactccaa atatacataa taaattaaaa aaagggaaag ttgctatatt gggattgggg
     8101 ggacttggtt ccaatatagc tatctcttta gctagaatag gagtgggaga acttttactt
     8161 atagattatg atgttgtaga accatctaat ttaaatagac aacagtattt tatagatgat
     8221 ataggaaaac taaaaactga tgccatgata gaaaatataa aaaaaataaa tccatttata
     8281 aaattaaata aacgagatat ttttttaaac aagaacaata tggatactat taaggattca
     8341 gatttaataa ttgaggcctt tgatgatgct tcatgtaaag cacaggtatg taattatgta
     8401 ttaataaatt taaaagataa atatttaata gcatcatctg gtatggcagg ttactatgat
     8461 tcaaatataa taactactaa gaagataaaa gacaggtttt atatatgtgg ggattttgtg
     8521 aatgaagcta aatttggtga agggcttatg gctccaaggg ttgccatctg cgcaaatcat
     8581 atggcaaatt tggcaacgca aatacttata gatatgtaaa tattaaaatt agatataaaa
     8641 aagattgaat attaaaaaaa tttaacgtgg agggaaataa tatggataaa ttggtacttg
     8701 gtggacatga atttaatagc agattattgg ttggaacagg taaatatggt tcaaataata
     8761 tattgcctga ggtaataaaa gaaagtggaa gtgaaataat aacaatggca cttagaagag
     8821 tggatttaga caataaacaa gaaaacatat taacgtatat tccaaaagag atgacaatac
     8881 ttccaaatac atcaggagct actaatgcag aagaagctgt aagaatagct agaatatcta
     8941 gaaaaatggg atgtggagat tttataaaaa tagaagtaat atcagatact agatatttac
     9001 ttcctgataa tgaagaaact ataaaagcta caaagatact tgctgatgag gggtttatag
     9061 ttcttccata tatgacacca gacctttatg ctggaagaag acttatagaa gctaatgcag
     9121 ccgcagttat gccacttgga gctccaattg gttcaaatag aggtcttcaa atgaaagaaa
     9181 tgataagaat aatgatagat gagttggata taccaataat agtagatgca ggtattggaa
     9241 aaccatctca agctatggag gctatggaaa tgggagctga tgcagtactt gtcaacactg
     9301 ctatagcttc agcaggagac cctgtacaaa tggctagagc atttaaatta gctgtagaag
     9361 gtggaagaga agcatatatt gcaaaaacag gaaatgtgtc agaatttgca aatgcatctt
     9421 ctcctttaac aggtttttta ggcaatttat agaaagtggt gattggtgat gagtttttat
     9481 gatgtaatag aaaaatatag ggattttgat tttgatggat atttaaataa tgttactgat
     9541 aatgatgttt taagaagttt atcaaaagac aagcttgaag attttgatat attaaatttg
     9601 ctttctaaaa ctgcagtaaa acatttagaa gatatggcac aaaaagcaca taaattaagt
     9661 gttcaatact ttggtaaaac agtatgttta tatacaccaa tgtatatagc aaattattgt
     9721 gttaatcaat gtgtttattg tagctataat ataaagagtg gaataaaaag aaaaaaatta
     9781 actatggatg aaattagaga agagggagaa gcaatttcaa aagaaggttt caaacatcta
     9841 cttgttttga ctggagaaag tagttttcac tcaagtgtag aatatatagg tgaggctata
     9901 gaaatattaa gagagaaatt tccctctata ggtatagaag tttatccaat ggaagtagaa
     9961 gaatataagt acattgtaga taaaggtgtt gaaggattaa cagtatatca agaaacttat
    10021 gacgaggaaa tatataagag agtacatata aaaggcccaa aatcaaatta tgaatttaga
    10081 ctagatgctc ctgaaagagg ggcaaaagca ggtatgagga ctttatcaat aggtgcactt
    10141 ttaggtctaa atgattttag aaaagaaact ttttttacaa tattgcatgg gaaatactta
    10201 aaaacgaaat atcctcatat tgagctttca tattcaacac caagaatgag accttttaaa
    10261 gggtgttttg aggaattggt agatataagt gatactgatt tagttcaagc tatggtatgt
    10321 atgagattat ttgaccctca tgcagctata aatatatcca ctagagaaaa tttagaaatg
    10381 agaagtcata taataccttt aggagtaact aaattgagcg caggtgtatc tactgatgta
    10441 ggaggtcatt ctcaagatga acatgatact gctcaattta agataaatga tgaaagtact
    10501 gttaaagatg tggagaaaat gctaaactca attggttatc agcatgtgtt taaagattgg
    10561 gaaagatttt aaatgtatct gataacaaac agaaaattat gtagtgagga acgatattta
    10621 gaagttatta aagagtctat attgagtggt gtagaaaata taataataag agaaaaggat
    10681 ttggaatatc aagagctaag aaaattatat atgaaaataa aaactaaaat caattgtata
    10741 gattttcaag agcaaatatc agatgaaagt ttgaaaacta atataaatca aaaagagtgt
    10801 agaaataaat tcaaggttaa ttttataata aatagtaaca ttgaattttt tgaaaaagtg
    10861 gattgtcaag gtatccatct tccttttaaa ttattcttga atttaattga aaataagtat
    10921 aattttaatg aaaataaaat actaggatta tctttacata aagtagagga agtagattat
    10981 ttagaaaaat taataagaaa tcaaaatata aaaatagatt acataacatt atcacatata
    11041 tatgaaacta aatgtaaaga aggattaaat ccaaaaggaa ttgagctttt aaaagaagct
    11101 aaaaagatta ctgatattaa aataattgca cttgggggaa ttttaccatc taatgtcaaa
    11161 gaaacattaa aatactgcga tgattttgct ataatgtcaa ctataatgag gtctaaagat
    11221 attaaaaaaa ccatatcaaa ttataatgaa aagttgaatt agtaaatata gtatattgaa
    11281 tttttaactt aaataaaaat aaaaaagtta tcttttaaat tttaaaaggt agctttttta
    11341 ttttatatct ttgctaataa aaaattgtaa aaagggaaaa ctttagtcag agagattaaa
    11401 caatatccta gaaagattta aaatttagta aagtatggag gacattataa tgactgacag
    11461 taaaaagaaa cgatttatta taccacacac ttttacaata atatttttac taatagtctt
    11521 gatggcaata ttgacttgga tagtaccaag tggtgaattt agtagagaag atgtagaagg
    11581 tagaatggta gttgtaccag ggacttatca aagtgtagaa agtaatcctc aaggatttgc
    11641 agatgttttt aaagcaccaa tagaaggctt tatagattca gctgaagttg taggttttgt
    11701 tttaatagtt ggaggtgctt ttggtattgt aaataggact ggagctatag aagcaggaat
    11761 agcttcggtt atctctaagt ttaagggaaa agaacttctt ataattccaa tatcaatgat
    11821 tttatttgga cttggaggta caacatttgg gatggcagaa gagacattac cattttatat
    11881 gatatttgtt ccactcatga catccttggg atatgattct ctaacagcaa tagcaattgt
    11941 atttatagga gcagcagcag gagccgccgc ttcaacaata aatccatttt cagttggtat
    12001 tgcacaggca ctagctcaac ttgctcctgg ttcaggagta acttacagag tagttatttt
    12061 tatagcatat atactaataa gtatagcatt tgttatgtac tatgctaaga aggtaaagga
    12121 aaatcctgaa agttcaatag tatatgaaat agataaaaat aataaatcaa tacttaatca
    12181 aacttcaaca gaaataaaag aatttacttt taaagaagta tctgttcttg ctatatttgg
    12241 aatagggatg gcaataatga tttggggtgt tttaagtcaa ggatggtaca ttccagaaat
    12301 atcaatgtgt tttgctgcaa taggtgtgct ttctggattg gttggtagat tatctcaaat
    12361 tgaaatctca gaaagtttta tagatggagc aaaagattta gcatctgcag ctcttgctat
    12421 agctttggct cgtggaatcg taataattgc tcaaaatgga tttataatag atactatatt
    12481 aaattccgca gcagcctttc taggtgggct tccaaaggtt atatttgtat atttatcatt
    12541 tttcttggaa gctgcattgg catttttaat tccatcatct tcaggtcttg cttcacttac
    12601 agtacctgta cttgctcctc ttggtgattt ggttaatata tcggctcaag tgatagtaac
    12661 cgcttatcaa tttggtgtgg gtcttacaaa ctttataact ccaacttcag gagtactgat
    12721 gggagcactt gcagtagccc atattccatt ttcaaaatgg gtaagattta taatgcctat
    12781 cttgttgatt ttgacagctg tatctctagt ctttttaaca ataggtattt atatagggtt
    12841 ttaattaagt gtagttttat ttaagatatt tagtaatggt ataaaatgat aatatgtttt
    12901 caataaattg ccactaattt aattagtggt aatttatttt ttgtatttaa aaataaatgt
    12961 atttacttgt attttgaatt aatatct
//
LOCUS       DAMJYN010000096        12930 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.100, whole genome shotgun sequence.
ACCESSION   DAMJYN010000096 DAMJYN010000000
VERSION     DAMJYN010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12930)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12930)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12930
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.100"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            176..364
                     /locus_tag="PC466_003103"
     CDS             176..364
                     /locus_tag="PC466_003103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HDF2770464.1"
                     /translation="MAKVCSVCDKGKVSGNQVSHSNKHNKRTWSANLRSVRAIIDGAP
                     KRVKVCTRCLRSGKIERA"
     gene            complement(524..676)
                     /locus_tag="PC466_003104"
     CDS             complement(524..676)
                     /locus_tag="PC466_003104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate translocator"
                     /protein_id="HDF2770465.1"
                     /translation="MRNNKSKVLLGILCLATGMAVILSMLLPGWIWSALTALILIGCG
                     ALLFFC"
     gene            complement(774..1250)
                     /locus_tag="PC466_003105"
     CDS             complement(774..1250)
                     /locus_tag="PC466_003105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HDF2770466.1"
                     /translation="MNLKRSNEKREEYRRMYSDKESFLSLIQNFTSVSIAKELTLKNI
                     ELETSFICEYKGKEVDIIYKVFSKSGKVSHYIVLEFQTEMDTEIVPRLKSYREQIWKS
                     FIMKKSLEEIEDKNFKLPKVIPVVLYSGPERLSRKKGILDIVESISEFSNNSSMKN"
     gene            1469..2230
                     /locus_tag="PC466_003106"
     CDS             1469..2230
                     /locus_tag="PC466_003106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF2770467.1"
                     /translation="MEYTVQKLSKLAGISTRTLRYYDEIGLLKPLKINSSGYRIYGQN
                     EVNKLQQILFYRELGINLENIKNIINSPNFDSLSALKEHHNKLLAKRKQIDLLIENVT
                     KTIALKEGKYTMTDIEKFEGFKEKMIDENEKNYGTEIREKYGKDIIDTSNKKLKNMSK
                     QDYENWQNLNIEIISKLKKAFKTGDASSELAQEVAKLHHKWLSYTWNTYSKEAHSSLA
                     QMYVYDERFTSYYDREQPGLAKFLRDAIVIYTRDK"
     gene            complement(2490..4418)
                     /locus_tag="PC466_003107"
     CDS             complement(2490..4418)
                     /locus_tag="PC466_003107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDF2770468.1"
                     /translation="MHKRLLTLFKLLNESDDKITCKTLSNHLKVSERTIRNDITSING
                     TLEKNGAIIKIKKGEGYYIDILNLALYQQYLALISDDIMDSSEIPDSPIERNQYILKY
                     ILYNNTYIKLEDLANSLYVSKFTILNDIKRIKPILSKYNLILVSKPYYGVKVEGKEID
                     IRRCISNNMINRNFENYIIGITDREIELFNNVDLIELQRVVLSEINKFNINFLDFNLK
                     NFIIHLAITISRILDGYCLDNVLDVVLTDFQSNTTVENIFNYIESKYTIIISKADRVY
                     LYNHFITKSSLLDNVSNRVDTKIIEYVEEILEVINNQYTFDLRNDSVLFDDLVLHFKS
                     ILNSKSYNLNKVNPLINTIKSNYPLAFEITLNAIEKVFKNSIYSLTEDEIGYVSLHIG
                     AGIERFFQNNIKCKNVVLVCGSGYGSSRLLEVQLNKVFHDKINILQCLSFNQFLASEL
                     SDVDIIISTIPLNHDSIPIVLVDLKLLKKDIENISKSITNNSHIYSNLLDNFFDKNLF
                     IVNPKIKDKDELIKLMCNKLTQSEIVFPSFAESVFYRESLSSTNIDDFLAIPHPMELS
                     SIRTKICISILNEPIYWSEDSTVKLIMMLAINKDDYIKINSIYDILLKIIHDNDIRDS
                     ISNCNDFDNFLSIIKSIV"
     gene            4652..5104
                     /locus_tag="PC466_003108"
     CDS             4652..5104
                     /locus_tag="PC466_003108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2770469.1"
                     /translation="MVLQEKYIFIDKDLKSKEEVLNFIADSAYILGIATNKEALLKDL
                     LKRENEFPTGIKDGFAIPHTKSVNVKEASILYIKTTNELEWKTLDDSKVRYVFSLLAP
                     HKNEGNIHLKTLSKLATCLMEDDFTSEVKNASDASHLVKYITNKMKEE"
     gene            5107..5415
                     /locus_tag="PC466_003109"
     CDS             5107..5415
                     /locus_tag="PC466_003109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HDF2770470.1"
                     /translation="MKIVAITSCIAGLAHTPMAAKALEQAASKMGHEIKVEQQGAMGR
                     VNTITKEEAQDADFILIASDQTISGMERFDGKKVIKVKIGIALKKPEAVLTKCIEAIS
                     "
     gene            5529..6635
                     /locus_tag="PC466_003110"
     CDS             5529..6635
                     /locus_tag="PC466_003110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HDF2770471.1"
                     /translation="MSKKNKSLLSELKGHLMTGISYMLPLVIGSSLVVAIPKLTALAM
                     GITSLDAYKNVSGFYHILYLMEQVGWTGIGLLNTVLAGFIAFSIGEKPAMGAGFIGGL
                     IASNTNAGFLGAVIAGFFAGYVCKFLKKKIKISGSASGMMPLIIMPLITVGLTGFLMS
                     VVLAGPLGNINTSLNAWVAEMCQNGTNSVVLALILGAMIGFDLGGPVNKAAWMAGNAL
                     LLEGIYLPAILVNCAIVIPPLGYGLATFIRKSKFSNALAETGKGNIVMGIIGITEGAI
                     PFTLTNPLKLVPVNMIGCALGVGLSALLGVHAIMPPVGGLYGFISIGSGWAYLVGAIF
                     GALVIAILSTTLVDFNEDETTENTEFDEIELDIM"
     gene            6710..9388
                     /gene="mngB"
                     /locus_tag="PC466_003111"
     CDS             6710..9388
                     /gene="mngB"
                     /locus_tag="PC466_003111"
                     /EC_number="3.2.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosylglycerate hydrolase"
                     /protein_id="HDF2770472.1"
                     /translation="MKKTKVHVVPHSHWDREWYFTTSRSKIYLMKDFQDILDILEEKE
                     DFKYFTMDAQASLLDDYLKWRPQDEYRIRDLVQRRRLVIGPWYTQTDQLVISGESIIR
                     NLYYGIDRCNEFGEPMRVGYVPDSFGQSAQMPQIYRGFGIDSSLFWRGVSDDMVDTTE
                     FIWKGSDGSKVLAVQIPFGYYYGGNIPEDDSDLKEYLKDIIGKLKVKASTNNVYFPNG
                     FDQAPIRKNLPDILKKANEIDNENEYEISNIENYIDSVKNERNEFTELKGEFLNAKHM
                     RIHKSIFSSRSDLKIMNNKLENYITNVLEPLLTLSYSLGNEYPHLVIKDIWKLMFENA
                     AHDSIGSCNSDTANEDVYTRYKQARDLSINLLDLHMRLISTQIKNNNEEITLTVFNGF
                     PEVRNEVVEFDTYIPGQDFVIKNKNGEILNYIIKEKEDITNYILTQTIRLNPSKKIYI
                     PKTVYRAKIALSVKDIPPMGYTQLVFELDTKNKCEIETSNCKEIENKYYKITANKNGS
                     LEILDKESSKTYKNQAVIEDNGDDGDSYNYSPPRKDIYVSSLDSVSSVEVLKSNIQEE
                     MILKYSLTIPASLEERSIGKVSVKMPVTMKITLEPKEQIIKFNVNIKNNQALSHRVRV
                     LFNTEIASKFSIADQQFGIIQRPTVLEKDLALWKRDNYSWQEKPITIEPMQSFVTLED
                     GQRGIALITGCVREYQIVGDNLDTIALTLFRSFGYMGRENLLYRPGRASGEKIIATPD
                     AQLLKELNFDFGLYIYNNKFDEANVANTAKRFLTPIQIYEYADFLNGRLLFAFNDEKQ
                     IYENEFSLMNVNNSNFTVSAIKKEEKGDGIVVRIFNGMKNEDAKGSLNINKNVNDAYS
                     AMLDEIYDNNSKLKVNTKTVEVNSLSHCKVQTIVIK"
     gene            complement(9705..12038)
                     /locus_tag="PC466_003112"
     CDS             complement(9705..12038)
                     /locus_tag="PC466_003112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDF2770473.1"
                     /translation="MDTKLKKFKDKYIVTIIVFILMLSASLGMISQYSTIQAGAKGGA
                     KNPFEQESFVDSIYKGSYVLYHNMKEEQEGKMIQPSKLFINEETMNYIKNVSKEKDTY
                     DGSETYYTDDSINADFNENFENWEHFIKASGKNLKYYLVDKESNFEFFNDNKELGVLD
                     TTKNDASKENSDENQSKNTEMNDEERQKQITDIKENYRFYVVMNFDKDGKVNIVDSYG
                     VNQKVINQMLLSKAREDLMDTSLGGNSISYKLSPIKNITLVYAVPKVISKGDSVEYGY
                     GNTYFDDGIISYISNVENNSYYKISGMILKIILAIVVIVALAFPYRKSKELLGFDTLL
                     RIPLEILFIALAIIQGLVDLYPTVIISNTLSGNYVEYLINNDISAKMASILVSLMNLT
                     YWFVIFSIIFVFIILLKHILNVGIREYFTKHTVTGMFFVWLKKAGKTVINQIRTINLK
                     EKPNKTIVTILGINLLIIVIMCSMWFFGIILALIYSVVLFKILSDYSKKTIYEYNQLL
                     DVTKKISDGNLDVNMEKDLGFFNPIKDELGNIQTGFKKAVDEEVKSQKMKTELISNVS
                     HDLKTPLTSIITYIDLLKDESITDENRKLYIDTLDRKSQRLQHLIEDLFEVSKANSGD
                     VYLNIVNVDIVSLMKQTLLELDDKLADSSLIVKNNFSNEKIILPLDSQRTFRVFENLI
                     INISKYAMPNSRVYIDILETDNKVNIMLKNMSASEIDFSVDDIMERFVRGDKSRNTEG
                     SGLGLAIAKSFIELQGGKMNISVDGDLFKVTITFNKN"
     gene            complement(12013..12729)
                     /locus_tag="PC466_003113"
     CDS             complement(12013..12729)
                     /locus_tag="PC466_003113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2770474.1"
                     /translation="MNSYNILVVEDEKEIADAIEIYLLNQGYNVFKGYNGLEGLKVIE
                     NQEIHLAIVDIMMPKMDGITLTMRLRENYNFPVIMLSAKSEEVDKIMGLNIGADDYVT
                     KPFKPLELLARVNSQLRRYTKYLNMVGNKEQKVESDDSVFAIGGLELNENTKEVNIDG
                     KYIKTTPIEFKILSLLMRNAGRVFSADEIYERVWNENAINTDTVMVHVRNIREKIEID
                     PKNPKYLKVVWGVGYKIEKI"
BASE COUNT         4832 a         1794 c         1663 g         4641 t
ORIGIN      
        1 tttccaaata tatttacttt atataaaatt atatatataa ttttatatga taataagaaa
       61 ttcttcaata tgtgtaaggc aaatatatat ttctattgca aatttttgtt atttatgata
      121 atataaatat gtttttagtc tttaaatagt tatcatttta aggaggtgtg cgtagatggc
      181 aaaagtatgt agcgtatgtg ataaaggtaa ggtttctgga aaccaagtat cacactcaaa
      241 taaacataat aaaagaacat ggtcagctaa cttaagaagc gtaagagcga ttatagatgg
      301 agctcctaag agagtaaaag tttgtactag atgtttacgt tctggtaaaa ttgaaagagc
      361 ttagtaacca cgtttaaaag cctacttccg taagtaggct ttttaattta atcattttta
      421 ctctttctca taaattttag gattatactt gaaatccatt ttggtaattt tattgttact
      481 actttcatca atactcaccc cacactttat agttaaaact attttaacaa aaaaataata
      541 atgctccaca tccaataagt attaatgcgg taagtgctga ccaaatccag ccaggaagca
      601 acattgacag aattacagcc attcctgttg ctagacaaag tattcctagc aataccttag
      661 acttgttatt tctcatggaa cacctccaca tagaacctgt atctataaat attttcatat
      721 tcaagtttat gcgacagttt tccattttag accaataaac acattatgta attttaattt
      781 ttcatactag aattattact gaactccgat atagattcta caatatccaa aattcctttt
      841 tttctactta acctttcagg tccactatat aaaaccactg gtataacttt aggaagttta
      901 aaatttttat cttctatttc ttcaaggctt tttttcataa taaaactttt ccaaatttgt
      961 tctctatacg atttcaatct tgggacaatt tcagtatcca tttctgtttg aaattctaac
     1021 actatataat gtgatacttt gccactttta gaaaatacct tataaattat atcaacttct
     1081 tttcctttat attcacatat aaaagatgtt tctaactcta tatttttaag agttaattct
     1141 tttgctattg agacacttgt aaaattttga atcaaactta aaaaactttc tttatctgaa
     1201 tacattcttc tgtactcttc tcgtttttca ttgcttcttt ttaaattcat acagttcctc
     1261 ctaggctata gaccttctat attttagtaa agatagtcta taaattttat tttttaattt
     1321 tcattagtga gtattgacag ttgtgtgtaa aatatccagt aaagatattt ttttatattt
     1381 ttattaaaag atataaattt ttatatttta atatattgac atttacgttg cgtaaaagtg
     1441 tatatttaat ttataggagg tattacttat ggaatataca gttcaaaaat taagtaaact
     1501 agctggtata agtactagaa cacttagata ttatgatgaa ataggtcttc ttaagccact
     1561 taaaataaat tcttcaggtt atcgtatata tggtcaaaat gaagttaata aacttcaaca
     1621 aatacttttt tatagagaat taggaattaa cttagaaaat ataaaaaaca ttataaattc
     1681 accaaacttc gatagtttaa gtgcgttaaa agaacaccat aataaattac tagccaaaag
     1741 aaagcaaatt gatttactaa tagaaaatgt aactaaaact atagctctga aggagggaaa
     1801 atacactatg acagatatag aaaaatttga aggttttaaa gaaaagatga ttgatgaaaa
     1861 tgaaaaaaat tatggaactg aaattagaga gaaatatggt aaagatatta tagatacatc
     1921 aaataaaaag cttaaaaata tgtctaagca agattatgaa aattggcaaa acctaaatat
     1981 cgaaataatt agtaaactta aaaaagcttt taaaactggt gatgcctcta gtgaactggc
     2041 tcaggaagtt gcaaaattac atcataaatg gttgagttac acttggaaca catactctaa
     2101 agaagctcat tcctctctag cacagatgta tgtatatgat gaacgtttta catcatatta
     2161 tgatagagaa caacctggat tagctaagtt tttaagggat gctatagtaa tatatacaag
     2221 agataaataa tataaaataa taaaggtggt gtctcaaaat gaacttttta gttcatgaga
     2281 cactcttttt tgtatgaaat caaatatatt tttatcattt tatcaatgaa aaacaagttt
     2341 ctctctctat tttgagacag aatctttatt gtataataat tataatcaat acaaaataat
     2401 aacaaattat acaaaactta cttatactat ttatgctaaa aacaaaaaat attttattaa
     2461 agtttttaaa acttatgtaa tataaaaatc tatactatag acttgattat ggaaagaaaa
     2521 ttatcaaaat cattacaatt agatatacta tctctaatat cattgtcatg aattatcttt
     2581 aaaaggatat cataaatgga gtttattttt atataatcat ctttatttat agctaacatc
     2641 atgattaatt taacagtaga atcttcactc caatatattg gttcattcaa tatggaaata
     2701 caaatcttag ttcttataga gcttaattcc ataggatgag gtatagctaa aaaatcatct
     2761 atattggtag aagataaact ttctctgtaa aatacagatt cagcaaatga tggaaataca
     2821 atttcacttt gagttaattt gttgcacatc aactttataa gctcatcttt atctttgatt
     2881 ttaggattaa caataaataa atttttatca aagaaattgt ccaaaagatt actataaata
     2941 tgggaattat tagtgattga cttagatata ttctctatat ctttttttaa tagttttaaa
     3001 tccactaata caataggaat actatcatga tttaaaggaa ttgtcgatat tattatatct
     3061 acatctgaca attcactagc taaaaattga ttaaatgata gacattgaag tatatttatt
     3121 ttatcatgaa aaactttgtt taattgaacc tctaataacc tacttgaacc ataccctgaa
     3181 ccacatacta atactacgtt tttacactta atattatttt gaaaaaatct ctctattcca
     3241 gcacctatat gcagggatac atatccaatt tcatcttctg ttaaagagta aatactattt
     3301 ttaaaaactt tttctatagc atttaaagtt atttcaaatg ctaaaggata attactcttt
     3361 attgtattta taaggggatt caccttattt aaattataag atttagaatt gagaattgat
     3421 ttaaagtgca gtactaaatc atcaaataat acactatcat ttctaaggtc aaaagtatat
     3481 tgattgttga ttacttctaa aatttcttca acatactcta taattttagt atccacccta
     3541 ttggaaacgt tatccaaaag agaactttta gttataaaat gattatatag ataaactctg
     3601 tctgcctttg aaataattat agtatattta ctctcaatat aattaaatat attttcaaca
     3661 gttgtattcg attgaaaatc tgttaaaaca acatctaaaa cattatctaa gcagtaacca
     3721 tcaagtattc tacttatagt aatagctaaa tggataataa agttttttag attaaaatct
     3781 agaaaattta tattaaattt attaatttca cttaacacta ccctttgaag ctctattaaa
     3841 tctacattat taaataattc tatttctcta tctgtaattc caattatata gttttcaaaa
     3901 ttcctattta tcatattatt agaaatacat cttcgaatat ctatttcctt cccttcaact
     3961 ttaactccat aatatggctt agaaactaat attaaattat actttgacaa aataggcttt
     4021 attcttttta tgtcatttag tattgtaaat ttactcacat acaagctatt agctaaatct
     4081 tctagtttta tatatgtatt gttatagaga atatatttta aaatatattg atttctttct
     4141 ataggagaat ctggtatttc acttgaatcc ataatatcat cagatattaa tgctagatac
     4201 tgttggtata atgctaaatt aagaatatct atataatatc cttctccttt ttttatttta
     4261 ataatagcac catttttctc taaagttcca tttatagaag taatatcatt tcttatagtt
     4321 ctctcactca cttttaaatg attacttaaa gttttacaag taattttatc atcactttca
     4381 tttaataatt taaacaacgt gagcaatctc ttgtgcataa atatcccccc ttatagaatt
     4441 tcttctaaat tatactattt acactcatat aatacaatta ctctaataaa attgtattat
     4501 aataatttct ttccacttct atatggaaat tagttattat cataatataa atttccatgt
     4561 cgaagtggaa attagttata tttaatttaa ttaggataat gattacaata taaatataag
     4621 ttaagacatt acgaatggag tggaaaaata tatggtacta caagaaaaat atatatttat
     4681 agataaagac ttaaaaagca aagaagaagt attaaatttt attgcagata gtgcttatat
     4741 actaggtatt gcaactaata aagaggctct tttaaaagac cttctaaaaa gagaaaatga
     4801 atttccaaca ggaataaaag atggatttgc gatacctcat acaaaaagtg taaatgtaaa
     4861 ggaagcttcc atactctata ttaaaacaac taacgagtta gagtggaaaa ctttagatga
     4921 tagtaaggtt agatatgtat ttagtttgtt agccccacat aaaaatgaag gaaatataca
     4981 tttaaaaact ctatctaaat tagccacatg tttaatggag gatgatttta caagtgaagt
     5041 taaaaatgct agtgatgcaa gtcatttagt aaaatatata actaataaaa tgaaggagga
     5101 ataattatga aaatagtagc aataacatca tgtatagcag gattagcaca cacacctatg
     5161 gcagcaaaag ctttagaaca agctgcatca aaaatgggtc atgaaatcaa agtagaacaa
     5221 caaggtgcta tgggacgagt aaatactata acaaaagaag aagcacaaga tgcggacttt
     5281 atacttatag catctgacca aactatatct ggaatggaaa gatttgatgg taaaaaagtg
     5341 ataaaagtca aaataggtat agcgttaaaa aaaccagaag ctgtcttaac aaagtgtata
     5401 gaagctattt cttaataaaa aaatctcact ctaatataga atgagaaaaa taaaaaatta
     5461 aaaaattgtc taatgtaatt ataacatatt atcaaaaaat ataacaaact tatataggag
     5521 gattaaaaat gagtaaaaaa aataaatctc ttttaagtga acttaaggga cacttaatga
     5581 caggtatctc atatatgttg ccacttgtaa taggctcatc tttagttgta gctatcccaa
     5641 agcttacagc tttagcaatg ggtataacaa gtttagatgc ttataaaaat gtatctggtt
     5701 tttatcatat tctttactta atggaacaag ttggttggac tggcataggt ctattaaata
     5761 cggtattagc aggatttata gcattttcaa taggtgagaa accagctatg ggtgcaggtt
     5821 ttattggtgg gctcatagca agtaatacta atgcaggatt cttaggagca gtaatagcag
     5881 gtttctttgc tgggtatgtt tgtaagtttt taaagaaaaa aattaaaata tctgggtcag
     5941 catcaggaat gatgccactt ataataatgc cacttataac agttggatta actggttttt
     6001 taatgagtgt tgtattagca ggacctttag gaaacataaa tacttcatta aatgcttggg
     6061 tagctgaaat gtgtcaaaat ggaacaaatt cggtggtatt ggctttaatt ttaggcgcaa
     6121 tgataggatt cgatttaggt ggaccagtaa ataaagcagc ttggatggca ggaaatgcat
     6181 tattgttaga gggaatctat ctaccagcga tattggtaaa ctgcgcaata gttatacctc
     6241 cactaggata tggtttagct acattcataa gaaaatcaaa attttccaat gcattagctg
     6301 aaacaggaaa aggcaatata gttatgggta taattggaat aacagaaggt gcaattcctt
     6361 tcactttaac aaatccatta aaattagttc ctgttaatat gataggatgc gctttgggtg
     6421 taggattatc agctttgtta ggtgtacatg ctataatgcc tccagttggt ggattatatg
     6481 gatttatatc aataggttct ggatgggctt acttagtagg tgcaatattt ggagctttag
     6541 taatagcaat attatcaaca actttagtag acttcaatga agatgaaact acggaaaata
     6601 cagaatttga tgaaatagag ttagatataa tgtaaattaa aaacttaatt ttagataatt
     6661 gagaattgag tgtactctca attctcaatt aaattttggg aggattttta tgaaaaagac
     6721 aaaagtacat gtagttccac acagtcattg ggatagagaa tggtatttta caacatcaag
     6781 gtcaaaaata tatttaatga aagattttca agatatatta gacatattgg aagaaaaaga
     6841 ggactttaaa tactttacta tggatgcaca agcttctctc ttagatgatt atttaaaatg
     6901 gagacctcag gatgaatata gaataagaga tttagttcaa agaagaagat tagttattgg
     6961 accttggtat actcaaacag accaattggt tatatcagga gaatctataa ttagaaacct
     7021 ttactatgga atagatagat gcaatgaatt tggtgaacct atgagggttg gatatgtacc
     7081 agattctttt gggcaatcag ctcaaatgcc acaaatatac agaggttttg gaatagatag
     7141 ttcattattt tggcgtggag tttctgatga tatggtagat acaacagagt ttatatggaa
     7201 aggttctgat ggttcaaaag tattagcagt tcaaatacca tttggttatt actatggagg
     7261 taatatacca gaagatgatt cagatttaaa agaatattta aaagatataa ttggaaaact
     7321 taaggttaaa gcttctacta ataacgtata ttttccaaat ggatttgacc aagcaccaat
     7381 aagaaaaaac cttcctgata tattaaaaaa agctaatgaa atagataatg aaaatgaata
     7441 cgaaataagt aatatagaaa actatataga ttcagtaaaa aatgaaagaa atgaatttac
     7501 agagcttaaa ggtgaatttt taaatgctaa acatatgaga atacacaaat ccatattctc
     7561 ctcaaggtca gaccttaaaa taatgaataa caaattagaa aattatatca caaatgtact
     7621 tgaaccatta ttaacattaa gttattcact tggaaatgaa taccctcatc tagttataaa
     7681 agatatatgg aaacttatgt ttgaaaatgc agctcatgac agcataggtt cttgtaatag
     7741 tgacacagca aatgaggatg tatacacaag atacaaacaa gccagagatt tgagtataaa
     7801 tttattagat ttgcatatga gacttataag tactcaaatc aaaaataata atgaagaaat
     7861 aacattaaca gtattcaatg gattcccaga agtcagaaat gaagttgtag aatttgacac
     7921 ttatattcca ggtcaagatt ttgtgataaa gaataaaaat ggagaaattc ttaattatat
     7981 aataaaagaa aaagaagata ttacaaatta tatattaact caaacaataa gattaaaccc
     8041 aagtaaaaaa atatatatac ccaaaactgt atatagagca aaaattgcac tttcagtaaa
     8101 agatatacca ccaatgggat atactcaact agtttttgaa ttggatacta aaaataaatg
     8161 tgaaatagaa acaagtaatt gcaaagaaat agaaaacaaa tattacaaaa taacagccaa
     8221 taaaaatggt tcattagaaa tattagataa agaatctagt aagacttata aaaaccaagc
     8281 tgtaattgaa gacaatggag atgatggaga ttcatacaac tattctcctc caagaaaaga
     8341 tatttatgtt tcatctttag attctgtatc ttcagtagaa gtgctaaaat caaatattca
     8401 agaagaaatg atacttaaat attcattgac cataccagct tcactggaag aaaggtctat
     8461 aggtaaagtt tctgtgaaaa tgccagtaac aatgaaaatt accttagaac ctaaagaaca
     8521 aataattaag tttaatgtta atataaaaaa taaccaagca ctatctcata gagtaagagt
     8581 tttatttaat acagaaatag catctaagtt ttctatagca gatcaacaat ttggaataat
     8641 acaaagacca acagtattag aaaaagacct tgcattatgg aaaagagaca attactcatg
     8701 gcaagaaaaa cctataacta tcgaaccaat gcaaagtttt gttactttag aggatggaca
     8761 aagaggaata gcattaataa ctggttgtgt aagagaatat caaatagttg gtgataattt
     8821 agatacaata gcattaacac tattcaggtc atttggatat atgggaagag aaaatttact
     8881 ttatagacca ggaagagctt ctggagaaaa aataatagca acaccagatg cacaattact
     8941 taaagagtta aactttgact ttggtcttta catatataac aataaatttg atgaagcaaa
     9001 tgtagctaat acagctaaga gattcttaac acctatacaa atatatgaat atgctgattt
     9061 tttaaatggt agacttctat ttgcattcaa tgacgaaaaa caaatatatg aaaatgaatt
     9121 tagtttgatg aatgtaaata attcaaattt cacagtaagt gcaataaaga aagaagaaaa
     9181 aggagatgga attgtagtta gaatcttcaa tggtatgaaa aatgaggatg ctaagggaag
     9241 tcttaacatc aataaaaatg tcaatgatgc ttatagtgca atgctcgacg aaatctatga
     9301 taataatagc aagcttaaag taaatactaa aactgtagag gtaaattctt tatcacattg
     9361 taaagtacaa acaatagtaa ttaaataata taaaatagct tatacaagat ttcaaaataa
     9421 attgctagta ctatgttaat agtaaaccca gatattatgc tatttataag ctctgtaaca
     9481 ctaaataaca ttttgtaaaa taaaaaggtg aaccttgtat attaggattc acctttttta
     9541 aataaatcaa cattctgttt taaaataaca tttataagct gttttgaaat aatacttaca
     9601 aattatttta aaacaatacc tataaatttt tatttaaaga atacacataa atatttccag
     9661 actcttttat tctatagact ttataattat taaagaagtc taatctaatt tttgttaaaa
     9721 gtaattgtaa ctttaaataa atcaccatcc acacttatat tcatcttacc accctgtaat
     9781 tctataaaac tttttgctat tgctaaacca agaccagaac cttctgtgtt acgtgattta
     9841 tctcctctta caaatctctc cattatatca tctacactaa aatcaatctc agatgcagac
     9901 atatttttaa gcataatatt tactttatta tctgtttcta aaatatcaat atacactctt
     9961 gaatttggca ttgcatattt gcttatattt attataagat tttcaaatac tctaaatgta
    10021 cgctgactat ctaatggtaa tattattttt tcattagaaa agttattctt tactattaga
    10081 gatgaatctg caagtttgtc atctaattct aaaagtgtct gcttcattag agatacaata
    10141 tccacattta ctatattcaa ataaacatct ccactatttg ccttgcttac ttcaaacaaa
    10201 tcttctatta gatgttgcaa tctttgtgac tttctgtcta atgtatcaat atacaactta
    10261 cgattttcat ctgttatact ttcatctttt aataaatcta tataagtgat tatagatgtt
    10321 agaggtgttt ttaagtcatg tgatacattt gatataagct ctgttttcat cttttgactc
    10381 ttaacctctt cgtcaacagc ttttttaaat ccagtttgaa tatttcctaa ttcgtctttt
    10441 ataggattaa aaaatcctaa atctttttcc atatttacat ctaagtttcc atctgaaatt
    10501 ttctttgtaa catctaaaag ttgattatat tcatatattg tctttttaga gtaatctgac
    10561 agtatcttaa ataatactac tgaatatatt aatgcgagta ttattccaaa gaaccacata
    10621 ctacacatta taactataat caataaattt attcccaaaa ttgtaactat agttttattt
    10681 ggcttttctt ttagatttat tgttctaatt tgattaataa ctgtttttcc tgcttttttt
    10741 aaccatacaa aaaacattcc tgtcacagta tgttttgtaa aatactctct tattccaaca
    10801 tttaaaatat gttttaaaag tattataaat acaaatatta ttgagaatat tacaaaccaa
    10861 taagttaaat tcattaaact taccaatatg ctagccattt tagcacttat gtcattgttt
    10921 ataaggtact ctacataatt cccactcaag gtattactta ttataacagt aggatataaa
    10981 tctacaagcc cctgtataat agcaagagca ataaagagta tctctaacgg tattcttaat
    11041 aatgtatcaa atcctagcaa ctctttagat tttctatatg ggaatgctaa agctacaata
    11101 acaactatag ctaatataat ttttaaaatc attccagaaa tcttataata agaattattt
    11161 tctacattgc ttatatatga aattatacca tcatcaaaat aagtatttcc ataaccatac
    11221 tctacactat cacctttact tattacttta ggtacagcat atactaatgt tatatttttt
    11281 attggagata acttatatga aattgaattt cctcctaaac ttgtatccat taaatcttct
    11341 cttgctttag ataacaacat ttgattaata actttttgat ttactccata agaatccaca
    11401 atatttactt ttccatcttt atcaaaattc attacaacgt agaatctata gttttccttt
    11461 atatctgtaa tctgcttttg tctttcctca tcattcattt ctgtattttt tgactgattt
    11521 tcatcagaat tttcttttga agcatcattc tttgttgtat caagtactcc taattcttta
    11581 ttatcattaa aaaattcaaa attgctttct ttatcaacta aatagtactt taaattcttt
    11641 cctgacgctt taatgaaatg ctcccaattt tcaaagtttt cattaaaatc tgcattaata
    11701 ctatcatctg tataataagt ttctgaacca tcataagtat ctttttcttt acttacattt
    11761 tttatatagt tcatagtttc ttcattgata aatagctttg atggttgtat catcttacct
    11821 tcttgttctt ccttcatatt atgatataaa acataacttc ctttatatat actatctaca
    11881 aagctttcct gttcaaatgg attctttgct ccacctttag cacctgcttg tatagtagaa
    11941 tattgactaa tcatacctaa tgatgctgat aacataagta taaaaactat aatagtaact
    12001 atatatttat ctttaaattt tttcaatttt gtatccaaca ccccacacca cctttaaata
    12061 tttaggattt tttgggtcaa tttctatctt ttcccttata ttcctcacat gtaccataac
    12121 tgtatctgta tttatagcat tttcattcca aactctttca tatatttcat cagcagaaaa
    12181 aactcttcct gcatttctca taagtaaact tagtatttta aattctatag gagttgtttt
    12241 tatatatttt ccatcaatat taacttcttt tgtattttca tttaattcta atccgcctat
    12301 tgcaaacaca ctatcatcac tttctacctt ttgctcttta tttccaacca tgtttagata
    12361 cttagtgtac cttctaagtt gtgaattaac tctagccaat agttctaatg gcttaaaagg
    12421 ttttgttaca taatcgtctg ctcctatatt aagccccatt attttgtcaa cttcttctga
    12481 ttttgcagat agcattatta ctggaaaatt atagttttct ctaagcctca ttgtaagtgt
    12541 tataccatcc attttaggca tcattatatc aactatagct aaatgtattt cttggttttc
    12601 tataacctta agaccttcta atccattgta tcccttaaaa acattatatc cttgatttaa
    12661 tagatatatc tctatagcat ctgcgatctc cttttcatct tctaccacca aaatattata
    12721 tgaattcatt ttaatctcct ttatattaat ttataaattt tctttacata tatgattata
    12781 caatatgata gaagtttttc catttatata tatatttata tcttttgttc tggttatttg
    12841 tatttaatgt ccatcttaga aacctccttc tagtttaaac ttaatatttt ttcattttgt
    12901 tttatatact taatattaaa attaaaaact
//
LOCUS       DAMJYN010000097        12917 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.101, whole genome shotgun sequence.
ACCESSION   DAMJYN010000097 DAMJYN010000000
VERSION     DAMJYN010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12917)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12917)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12917
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.101"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            163..2022
                     /locus_tag="PC466_003114"
     CDS             163..2022
                     /locus_tag="PC466_003114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDF2770475.1"
                     /translation="MKRFLRRIILVLFILLIFISFISIKLIHNVGDYGKLINYVGIVC
                     GASQRLTKLEMNHQPNDELIEYIDEILQELITGHGDYGLVITDCNEYNEDLLLLEKKW
                     EDLNIEIKKVRMKEQNNQLLSISEEFFSLANDTVFKIENFSKEKSNYLMTLIIIISII
                     GILACIILILQYSKKMVRLEKLNVDLKNIAYKDELTGVNTIEKFKLDANQNICINKDK
                     KFAVFYIDFENFKYINDIFGYDYGDMILKRYANLMMNDIGKYEIFAREIADRFVALRC
                     YVDKEDLVVRQRDVDNELINITNEIKNKHSITVVSGICCIEDVNEKLSIDGLINRANF
                     AQKTVKNKPGTNYAFYNDSIRKKMIEENTIKSRIHEAIEKREFIVYLQPKVNLHSQKI
                     NCAEALVRWLTPDKGIISPAIFIPVLEKNFFIALVDKYVFEEVCKWIRKRLDENKPFV
                     QISVNVSRIQFYNTKFVETYSNIQNKYRIPKNTIEIEFTESVAFENQKHLLEIIHDLH
                     ENGFTCSLDDFGKGYSSLSVLKDLPFDVLKLDSMFFKASLDKDKEKIVIKNIVHMLKE
                     LNITTVAEGIECKEQVEFLRDIGCDLVQGFVFYKPMPILEFEEILDKEFVYNS"
     gene            complement(2314..2913)
                     /locus_tag="PC466_003115"
     CDS             complement(2314..2913)
                     /locus_tag="PC466_003115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HDF2770476.1"
                     /translation="MAIELKKGQKINLTKKENSDLGEILVNLNWNQKVQKKGFFGSLR
                     SSNIDLDLGCLFEMKNGVKGAVQALGNAFGSLDNPPFAQLDGDDRTGSNTQGENLRIN
                     GNKIKDIKRILIYAFIYEGVANWSEADGIVTIKQKQDSDLVVKLDEHKNGYNMCSIAL
                     IENVNDETFSVEKVVKYFKGHREMDTEFHWGLKWVAGRK"
     gene            complement(3016..3813)
                     /locus_tag="PC466_003116"
     CDS             complement(3016..3813)
                     /locus_tag="PC466_003116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HDF2770477.1"
                     /translation="MKFKKLLCLLLCLVLTLAVVGCSKAKDDKKIVVGATLVPGGELL
                     EELKPLIKEKGYTLEVKNFDDYILPNEALNNGEIDANLFQHEPYLKEAVKAKGYKIMA
                     GKKLYVCPAILYSYKIKSVDEFKKGDTIAISNNPSSCSKNLRYLESIGLLTLPKGDGL
                     VSPKDIIENPKGIQFKELDIAQIPSSLPDVTAAFIDTTYAVPAGLDAKKNGIYTAPIN
                     DEYANLLAFRTEDKDSEKIKVLQDVLTSDKARSLIEEKYKGIVIPTF"
     regulatory      complement(3926..4031)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            complement(4123..5109)
                     /locus_tag="PC466_003117"
     CDS             complement(4123..5109)
                     /locus_tag="PC466_003117"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HDF2770478.1"
                     /translation="MLLIYNEKTNPYFNLAMEEYLLKNFDEDLFILWRNEPSIIVGKN
                     QNTLSEINLEYIKEYSIPVVRRQSGGGAVFHDLGNINFTFIACNNNNFSDFRRFTQPI
                     IDLLKTLDVNAEFSGRNDLLIDGKKFSGNAQYNYKNKVMHHGTLLFSSEINDLSKALK
                     VKPIKFEGKGIKSVKSRVTNISEHLHSKMDILEFKDAIMDYLSKTNTDNTNYCLNEHD
                     IKQIEKLTKSKYETWDWNFGNSPKYTLSNELKYSGGNVEFNLNVDKGIITSIKFFGDF
                     FGKCDVAFVENKLIGIRHEENALRNTLDSIEINDYFLGADTDILVSGILGVK"
     gene            5593..7323
                     /locus_tag="PC466_003118"
     CDS             5593..7323
                     /locus_tag="PC466_003118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC family protein"
                     /protein_id="HDF2770479.1"
                     /translation="MRNKKINIIFLTTIMFIMSTVMVFAEEDIDTIALANAEKFGILT
                     LIPPLVAIILAFITKNVIISLLIGILSGSFIIKASGINVFATFIQAFLDLVDRALVSL
                     ADPWNAGIILQVLAIGGVINLVAKMGGAKAIAEALAKRAKSAKGTQLITWFLGLLVFF
                     DDYANSLIVGPMMRPVADKMKISREKLAFIIDATAAPVAGLAIISTWIGLEVGLIHDA
                     FESISIDVDAFGIFLNTIPFRFYNILILAFIVISALLLKEFGPMRKAEIKSRSRKISI
                     DLDEGVEELDDLAPKNGVKLSVWNAIIPIGTLIIVALASFYYSGYTSIMGGDDKALIQ
                     LFTNSPYSFEAIKEAFSASDASRALFQSALVASLVAIIMAVVKKIFTISEAIDVWIDG
                     MKSLVITGVILILAWSLSSVIKELGTAKFLIHLLSGSLPPFLLPSLIFGLGAIISFAT
                     GTAYGTMGILMPLAIPLAYSLNPDMSYVIVSTSAVLTGAIFGDHCSPISDTTILSSMG
                     AGCNHIDHVNTQMPYAIFTAVITIVFGYIPAGLGLPIYIVLPVAIAAIFVGIQIIGKK
                     VDEAEIELVE"
     gene            7433..7513
                     /locus_tag="PC466_003119"
     tRNA            7433..7513
                     /locus_tag="PC466_003119"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:7467..7469,aa:Leu,seq:tag)
     regulatory      8410..8514
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            8724..11198
                     /gene="gcvPA"
                     /locus_tag="PC466_003120"
     CDS             8724..11198
                     /gene="gcvPA"
                     /locus_tag="PC466_003120"
                     /EC_number="1.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminomethyl-transferring glycine dehydrogenase
                     subunit GcvPA"
                     /protein_id="HDF2770480.1"
                     /translation="MNELKRVSLYNIHKELGAKLVEFAGWEMPLEYEGINKEHEKVRK
                     SAGIFDVSHMGEVQIKGAESEKFIQNLVTNDISTLKINDIIYTPMCYENGGVVDDLLI
                     YKFGEEDYLLVINAGNIDKDVAWIIKQSEGYNVDIKNISSEVSQLAIQGPKAEEILQK
                     ITDIDLNSIKFYKSIPSTKVCGCPCLVSRTGYTGEDGFEIYCKNKYVEIIWNEVLKVG
                     GEDICPAGLGCRDTLRFEAALPLYGHEINEHISPIEGGLSIFVKTNKESFIGKSILSK
                     EKESGAKRKLVGFEMQGKGMPRNGYDIRIGDKTVGFVTTGCASPTTGKILGMGIIDSE
                     YAKVGNEIGIAIRKKVVPAVIVKKPFYKKQYKKDNIILNKENKFSYIPATSEDKSKML
                     KVVGLNSVDELFSDIPEEVKLKRDLNLEIGKSELEVSKIVKRLSEENLSLEDLTCFLG
                     AGAYDHYIPSIIKHITSRSEFYTAYTPYQAEISQGTLQVVFEFQSMIAEITGMEIANA
                     SMYDGATAAIEACIMAMNQTRKSKIVVSKTIHHETLSVLRTYLQYKDCEIVEIDFCNE
                     YGTTDIEKLKASVDKDTACVLIQTPNFFGIIEEMEEIEKITHENKAMLIMSVDPISLG
                     VLKTPGEIGADIVVGEAQSLGNPLNFGGPYVGFLASKSKYTRKMPGRIVGQSLDVEGK
                     IAYVLTLQTREQHVRREKATSNICSNQALNALVASIYMATMGKEGFKEVGMQSMKKAH
                     YTYNKLVQTGKYKPIFKGKFFKEFAVQGNLNIETINDKLLEENILGGYNLEYNYPELK
                     NSTLLCVTEKRSKEEIDKLVGIMEGL"
     gene            11198..12655
                     /gene="gcvPB"
                     /locus_tag="PC466_003121"
     CDS             11198..12655
                     /gene="gcvPB"
                     /locus_tag="PC466_003121"
                     /EC_number="1.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminomethyl-transferring glycine dehydrogenase
                     subunit GcvPB"
                     /protein_id="HDF2770481.1"
                     /translation="MKEYNSLLIDISKKGRKAYSLPKLDIDDIKIEDMIDQDMARQSE
                     LNLPEVGELELVRHYTLLSNKNFGVDTGFYPLGSCTMKYNPKINEDMAALPNFTGMHP
                     YQSSDTAQGSLSLMYDLSRRLAEITGMDEVTLQPSAGSHGEFTGLMIIKAYHENRGDH
                     KRTKVIIPDSAHGTNPASAAMANFDVIQIASDKNGAVDINALKEVLNDEVAALMLTNP
                     STLGLFEKNIKEIATLVHEAGGLLYYDGANMNAIMGITRPGDMGFDVVHLNLHKTFST
                     PHGGGGPGAGPVGVKKELVPFLPIPLIERKEDKYVLNYDREKSIGKIKNFYGNFGVLV
                     RAYTYILTMGRDGLKEASEMAVLNANYIKESIKDDYILPIDTLCKHEFVLGGLPRGEA
                     NIKTIDIAKRLLDYGYHPPTMYFPLIINEALMIEPTESESIETLDSFIEAMKSVAKEA
                     KEEPELLKTAPHNTLVKRVDDARAVKKPILTWSQR"
BASE COUNT         4842 a         1537 c         2138 g         4400 t
ORIGIN      
        1 ttttgtatat ataaaggact ctaaagatga actatataaa acaaggttta tatattctaa
       61 tagtatagaa aattttattg taaacgcatg tatattatta gaaaaaatag tttgaaggta
      121 ttcaataaac ataaaaaaca atatagggga taaaggtgtt ttatgaagag atttttgagg
      181 agaattatct tagttttatt tattttgttg atttttataa gttttatttc tattaaatta
      241 attcataatg ttggagatta tggaaaattg attaattatg ttgggattgt ttgtggagct
      301 agccaacgtc taactaaact agagatgaat catcaaccaa atgatgaatt aatagaatat
      361 attgatgaaa tcctacagga gttgattaca gggcatggag attatggttt agtaatcact
      421 gattgtaatg aatacaatga ggacttactt ttattagaaa aaaagtggga agatttaaat
      481 attgaaatta aaaaagtaag aatgaaagaa cagaataacc agttattaag tataagtgaa
      541 gagttttttt ctcttgcaaa tgatacagtg tttaaaatag aaaacttttc taaagaaaaa
      601 agtaattact taatgacttt aataataatt atatctatta taggtatatt agcatgtatc
      661 atattgattt tacaatatag taaaaaaatg gttagactgg aaaaattaaa tgtagattta
      721 aaaaatattg catataaaga tgaactaaca ggagtaaata ctatagaaaa atttaaattg
      781 gatgcaaatc aaaatatttg tataaataag gataagaaat ttgctgtatt ctatattgat
      841 tttgaaaact ttaaatacat taatgatata tttggatatg attatggtga catgatactg
      901 aaaagatatg ctaatcttat gatgaatgac atagggaaat atgaaatatt tgcaagagaa
      961 attgcagata gatttgttgc gttaagatgc tatgtagata aggaagattt agtagtaaga
     1021 caacgagatg tagacaatga actaattaat ataacaaatg aaattaaaaa taaacatagt
     1081 attactgttg tcagtggaat ttgttgcatt gaagatgtaa atgaaaaatt aagtatagat
     1141 ggtttaataa atagagcaaa ttttgcacaa aaaactgtta agaataaacc aggtactaat
     1201 tatgcttttt ataatgacag tattcgtaaa aaaatgattg aagaaaatac tatcaagagt
     1261 agaatacatg aagctattga aaaaagagaa tttatagttt atttacagcc taaagttaat
     1321 ttacatagtc aaaaaataaa ttgtgcagaa gctttagttc gttggcttac tccggataaa
     1381 ggtattatat ctccagcaat atttattcca gtacttgaga agaatttttt tattgcctta
     1441 gtagataagt atgtttttga ggaggtttgt aaatggatta gaaagaggtt agatgaaaat
     1501 aaaccttttg ttcagatatc agttaatgtt tcaagaatac aattttataa cactaaattt
     1561 gtagaaactt attccaatat acaaaataaa tacaggatac ctaaaaatac tatagaaatt
     1621 gaatttacag agagtgttgc ttttgagaat caaaaacatc ttttggaaat tatacatgat
     1681 ttgcatgaaa atggatttac ttgttcttta gatgattttg gaaaaggtta ttcgtcttta
     1741 agtgttttaa aagatttacc atttgatgtt ttaaagcttg actctatgtt tttcaaggct
     1801 agtttagata aagataaaga gaaaatagta ataaaaaata ttgtacatat gttaaaagag
     1861 cttaatatca caactgttgc tgagggcatt gaatgcaagg aacaagttga atttcttagg
     1921 gatattgggt gtgatttagt tcagggattt gtattttata aaccaatgcc aatattagaa
     1981 tttgaagaaa tattggataa agagtttgtt tataatagct aaaatgtact ttataaaata
     2041 tgaactaatt aagtaaaatt attttgtact gaataaattt ttactttatt tacagaatag
     2101 tgattattta cagaaaaggg cgaaaagtgt attcctttaa gtatgggatg gatagcacaa
     2161 ataggggaga aaaaatattg gccatataag aatgcataat aatataaata tttgaaaggt
     2221 cagcattata taaaaattaa aaagaaaata aataattttt ctataaaaaa gagactatga
     2281 gaaaagttac tcatagtctc ctaaataatg tatttatttt cttcctgcaa cccattttaa
     2341 gccccaatga aattcagtat ccatttctct atgacctttg aagtatttaa ctactttttc
     2401 aacactgaat gtctcatcat ttacattttc tatcaatgct attgaacaca tattatagcc
     2461 atttttatgt tcatcaagtt tgacaactaa gtctgaatct tgtttttgtt tgattgttac
     2521 aattccatca gcttcagacc agttagctac accttcgtat ataaaagcat aaataagtat
     2581 tctttttata tcttttattt tattaccatt tattcttaaa ttttctcctt gtgtattact
     2641 tcctgttctg tcatctccat ctaattgagc aaaaggtgga ttgtctaaac taccaaaagc
     2701 atttcctaat gcttgaacag caccttttac accatttttc atctcaaata ggcaacccaa
     2761 atctaaatct atattactgc ttcttaaaga gccaaaaaaa cccttttttt gtactttttg
     2821 attccaattt aaattaacta agatttcacc taaatcgcta ttttcctttt ttgtaaggtt
     2881 tattttttgt ccctttttta attctatagc catagtaatc ttcctccaca aacatagatt
     2941 tatttaaatg gtagcactta ataagtcaat attcaacaag attagaataa taatattaaa
     3001 actatactaa atatactaaa aagtaggaat cacaatacct ttgtattttt cttcaattaa
     3061 gcttcttgct ttatctgatg taagaacatc ttgtagaact ttaatctttt cactgtcttt
     3121 atcttcagtt ctaaatgcta aaagatttgc atactcgtca tttataggag ctgtataaat
     3181 tccgtttttc ttggcatcaa gaccagcagg tacagcataa gtagtatcta taaatgcagc
     3241 agtaacatct ggaagagaag atggaatttg agcaatatct aactctttga attgtattcc
     3301 ctttggattt tctattatgt ccttaggact aactaatcca tcccctttag gtaacgttaa
     3361 aagtccaata ctttcaaggt atctaaggtt cttagagcaa gaagatgggt tattgcttat
     3421 tgcaattgta tctccttttt taaattcatc aacagatttt atcttataag agtaaagtat
     3481 tgctgggcat acatatagtt ttttaccagc cattattttg taacctttgg ccttaacagc
     3541 ttcttttaga taaggttcat gttgaaatag atttgcatca atttcaccat tatttaaagc
     3601 ttcgtttgga agtatgtaat catcaaagtt tttaacttct aaagtatatc ctttttcttt
     3661 aataagtggt tttaattctt ctaataactc tcctcctgga actaaagtag caccaacaac
     3721 aattttttta tcatctttag ctttagaaca tccaaccaca gctaaagtta gtactagaca
     3781 taataacaaa cataataatt ttttgaattt catataaatt ccctcctgaa tataattgat
     3841 tagttaaaaa taaaatacca ttctttatca cactgcaaaa taaaaataag cctgagttta
     3901 aactcaggct ttaaaagcta atttagactc atctttcagt ataatactgc aggatttagc
     3961 accaatgtat ataaaaatat actggttgct gggtttcata gggccagtcc cttcaccact
     4021 ctggataaga agtatcaatt tttaattatg ttataaatat tatcatgatt ttttacgtct
     4081 gtaaacataa ttttataaat attttaaaat ctttaatgta ttttatttaa cacctaaaat
     4141 tccagaaact agaatatcag tatcagcacc taagaaatag tcatttattt caatagaatc
     4201 cagagtattt ctcaaagcat tttcttcatg ccttatacca ataagtttat tttctacaaa
     4261 tgcaacatca cattttccaa aaaaatctcc aaaaaatttt atactagtta ttatgccttt
     4321 atcaacattt aaattaaact caacatttcc accagaatat tttaattcat ttgaaagagt
     4381 atattttggt gaattaccaa aattccaatc ccaagtttcg tattttgatt tagtaagctt
     4441 ttctatttgt tttatatcat gctcattcaa acaataatta gtattatcag tatttgtttt
     4501 agaaagataa tccattatag catctttaaa ttctaatatg tccatttttg aatgtaaatg
     4561 ttcacttata ttggttacac gagattttac agattttatt ccttttcctt caaattttat
     4621 aggtttaacc tttaatgctt ttgagaggtc atttatttca gatgaaaata aaagagtacc
     4681 atgatgcatt actttgtttt tgtagttgta ttgagcattt ccagaaaatt tcttgccatc
     4741 tataagaagg tcatttcttc cagaaaattc ggcattgaca tctagtgttt taagtaaatc
     4801 tattatgggc tgagtgaatc ttctgaaatc actaaaatta ttattgttac aagctataaa
     4861 tgtaaaattt atatttccca aatcatgaaa tacagctcca ccaccagact gtctcctaac
     4921 gacaggtata gaatattctt ttatatattc taaatttatt tcagaaagtg tgttttggtt
     4981 ttttccaaca attatagaag gttcattcct ccataaaata aataagtctt catcaaaatt
     5041 ttttagaaga tattcttcca ttgctaaatt aaaataaggg tttgtttttt cattataaat
     5101 taataacatt aaagtagttc ctccatagaa ttgataaaat ttttattatg aatacaatta
     5161 attttataat tcgacaataa tataaaaact cctttaaatt agaaatttta aaaactacct
     5221 tgcaaagttt aaataaataa tatatactca aaatatgttt aataaaagtg aatagaaggg
     5281 tagaggcgca ataatctatc agtactaata aggagttaag cacagagagt tattaggaaa
     5341 ggagatattg ccgaagtttt ataatcgatg ctttaagatt atattgctgg gggtacatag
     5401 aaaatatgta caactgtcac aggtttattt gtggtgagct atcatttaag gaattatatt
     5461 atatttattt ttactattgt tgatatattg taatgtttaa gccttgagtg tttaccactc
     5521 aaggcttttt tagttttatt gtaacataat accctgtaca gttcacaaaa ttaaaaggag
     5581 agggagattt atatgaggaa caaaaaaatt aatattattt ttctgacgac aatcatgttc
     5641 ataatgtcaa cagtaatggt ttttgcagaa gaagatatag acactattgc actagctaat
     5701 gcagaaaaat ttgggatttt aactttaata ccaccattag ttgctataat acttgcattt
     5761 ataactaaaa acgtaataat ttctttactt ataggtattc tttctggtag ttttataatt
     5821 aaagctagtg gtattaatgt ttttgcgaca tttatacagg catttttaga tttagtagat
     5881 agagctttag tatctttagc agacccttgg aatgcaggga taatactaca ggttttggca
     5941 attggaggag taataaatct tgttgctaaa atgggaggag ctaaagctat agctgaagca
     6001 cttgctaaaa gagcaaagtc agcaaaaggg acacagctta taacatggtt tttggggctt
     6061 ttagtattct ttgatgatta tgccaattca ctaatagtag gtcctatgat gagacctgtt
     6121 gcagataaaa tgaaaatatc aagagaaaag ctagcattta taatagatgc cacagcagca
     6181 ccagttgctg gtttagctat aatatctaca tggataggtc ttgaggttgg tttaatacat
     6241 gatgcttttg aaagtataag tatagatgta gatgcatttg gtatattttt aaatacaata
     6301 ccatttagat tttacaatat attaatatta gctttcattg taatatcagc attattatta
     6361 aaagaatttg gtccaatgag aaaagctgag ataaaatcta gaagtagaaa aattagtata
     6421 gaccttgatg aaggcgtaga agagttggat gatttagctc caaaaaatgg agtaaaattg
     6481 agtgtatgga atgctataat cccaatagga acattgataa tagttgcatt agcatcattt
     6541 tattatagtg gatatacatc tataatggga ggagacgata aggctctgat acaactattt
     6601 acaaattctc catattcttt tgaagcaata aaagaagcat ttagtgcatc tgatgcatct
     6661 agagcattat ttcagtctgc acttgttgca agtttagttg ctattataat ggctgtagta
     6721 aaaaagattt ttacaatatc agaagcaatt gatgtttgga tagatggaat gaaaagttta
     6781 gtaatcactg gtgtaatatt aatacttgca tggtcattaa gttcagtaat aaaagagtta
     6841 ggtacagcta agtttttaat acacctatta tcaggttcac taccaccatt cttattacca
     6901 agtttaatat ttggtttagg agcaataata tcttttgcta ctggaacagc ttatggaaca
     6961 atgggtatac ttatgccact tgcaattcca ttagcatact cattaaatcc tgatatgtct
     7021 tatgtaatag taagtactag tgcagtttta acaggtgcaa tatttggaga ccattgttct
     7081 ccaatttcag atacaacaat actttcttca atgggagctg gctgtaatca tatagaccat
     7141 gttaacactc aaatgccata tgctatattt acagcagtaa tcactattgt atttgggtat
     7201 ataccagctg gacttggatt gccaatatat atagtattac cagtggcaat agctgctata
     7261 tttgtaggta ttcaaataat tggtaagaaa gttgatgaag cggaaataga acttgtagaa
     7321 taaagatata aataagtttc accttttatt atcactattt tgttagtttt tagataattt
     7381 taaaaagtta ttgaaaataa tggcgaaata tagtaaaata aaagagtgat aagcggatgt
     7441 ggcggaattg gcagacgcac tagacttagg atctagcgcc attggcgtgg gggttcgact
     7501 cccttcatcc gcactttaca gtacttaatt gtactgaaaa aaactggggt tgctggcttt
     7561 cggagtgggc tatcccgttt ttattttttt gtatatataa tagattggca ctttagtata
     7621 aggtgctttt tttataggca aaaacagtac atttatttct gttttattat cattcatcta
     7681 ttagaatata ctttatttaa gaatgtgtta ataagcagtg ttcacattct tgataaaatg
     7741 tggaataata tgcctaccaa taagcatttg gtgtataagt aagagtattt atatagttga
     7801 ttgtgaaatg agtacaacaa ttctgtacag tataattggc attataattg tagcattgaa
     7861 tttaaagttt gcacagtcgc tgattggaaa atttacaaag tggatgtcaa acatataaat
     7921 tttagtttat tggacagttc aaggaatcag aaattggaat tttatagtat taatatttta
     7981 tagtattaat ataatgtata aaattttata gcaatgtatt tcataagtat aaagtgacta
     8041 gaattttaag aaatatacaa attctataaa aactaaataa tttcaagtat attttaaaaa
     8101 tcttattttt cacaagttta aaattgtaaa cgatttcatc aagtctatga atatactttt
     8161 aacatgttat agtaaatctc aatataaatt tacatttggt tctttgtgtg ttattttaat
     8221 aataaattaa gtgaaaatgt tattttacat taatatataa tatctttgca taagagtgaa
     8281 taatataaaa gagaaagaat tgataataaa aacttaacaa aaaaattaat acataaaaaa
     8341 aaataaatat aatgtgttga catttaattg aaatattcat acaataaaat tgaaaataaa
     8401 tatttccaaa tgagattagc gagagagtcc tttatacgaa aaggcgccga agaagaaatt
     8461 taagaaatgc caatttttag agaagctttc aggcaaaaat atcgctaatt gatgggactc
     8521 tggagagact taagttaaga tactataagt caccgaagaa gcaaaataat attaaattat
     8581 taaatctttc aggtatacaa acagggatat ataggctagg attattttcc atgctgatat
     8641 atcttttttt tatgaaaaag tacaggaaat aatatcaaag ttacttaaat acagtaggtc
     8701 taattttcta gggagggtta tatatgaatg aattgaaaag agtatctttg tacaatatac
     8761 acaaagagct tggagcaaaa cttgttgaat ttgctggctg ggaaatgcct ttagaatatg
     8821 agggtataaa taaagagcat gagaaggtta gaaaaagtgc aggtatattt gatgtatctc
     8881 atatgggaga ggtacagata aagggagcag agtcagaaaa atttatacaa aacctagtta
     8941 caaatgatat aagcacatta aagataaatg acattatata tacacctatg tgttatgaaa
     9001 atggtggagt agttgatgat ttattaatat ataaatttgg tgaagaagat tatttattag
     9061 taataaatgc aggtaatata gataaagatg tagcatggat aataaaacaa agtgaaggat
     9121 acaatgtaga tataaaaaat atatctagtg aagtgagtca attagcaatt caaggaccta
     9181 aagcagaaga aattcttcaa aaaatcacag atatagactt aaactcaata aaattttata
     9241 agtcaattcc atcaacaaaa gtatgtggtt gtccttgttt agtttcaaga acaggatata
     9301 ctggggaaga tgggtttgag atatactgta aaaataaata tgtagaaata atttggaatg
     9361 aagttctaaa ggttggagga gaagatatat gtccagctgg tctaggttgt agggatactt
     9421 tgagatttga agcagctcta cctctatatg gtcatgaaat aaatgaacac atatctccaa
     9481 ttgaaggtgg tttatctata tttgtgaaaa caaataaaga atcatttatt ggtaaatcaa
     9541 ttttatcaaa agaaaaagaa agtggagcta aaagaaagtt agtaggattt gaaatgcaag
     9601 gtaaaggaat gcctagaaat ggatatgata taaggattgg tgataaaaca gttggatttg
     9661 taacaacagg atgtgcatct ccaacgacag gaaaaatttt aggtatggga attatagatt
     9721 ctgaatatgc aaaagtagga aatgaaatag gtatagcaat cagaaaaaaa gttgttcctg
     9781 ctgtgatagt taagaaacct ttttataaaa aacaatataa aaaagataat attatattaa
     9841 acaaagaaaa taaattttca tatatacctg ctacaagtga agataaatca aaaatgttaa
     9901 aagtagttgg attaaattcg gttgatgaat tattttcaga tataccagaa gaagtaaaat
     9961 taaaaagaga tttaaatttg gaaattggaa aatctgaatt agaggtaagc aaaatagtaa
    10021 aaagattgtc agaagaaaac ttaagtttag aagacttgac ttgttttctt ggtgctggtg
    10081 catatgacca ttatatacca tcaattataa aacatataac ttcaagatct gaattttata
    10141 cagcatacac tccatatcaa gctgaaataa gtcagggaac tttacaagta gtttttgaat
    10201 ttcaatctat gattgcagaa attacaggta tggaaattgc aaatgcatca atgtatgatg
    10261 gagcaactgc tgcaatagaa gcatgtataa tggcaatgaa tcagactaga aaaagtaaaa
    10321 tagtagtgtc aaaaactatt catcatgaaa ctttgtcagt attaagaact tacttacaat
    10381 ataaagattg tgagatagta gaaattgact tttgtaatga atatgggact acagatatag
    10441 aaaaattaaa agcttctgta gacaaggata cagcatgtgt tcttatacaa actcctaatt
    10501 tctttggaat tattgaagaa atggaagaaa tagaaaagat aactcatgaa aataaggcta
    10561 tgttaattat gagtgtagac ccaatatcat taggagtttt aaaaacacca ggtgagatag
    10621 gtgcagatat tgttgttgga gaagctcaat cacttggaaa ccctcttaat tttggaggtc
    10681 cttatgtagg atttttagct agcaaatcta aatatactag aaaaatgcca ggaagaatag
    10741 ttgggcaaag tttagatgta gaaggtaaaa ttgcatatgt attaacttta caaactagag
    10801 aacagcatgt aagaagagaa aaagcaactt ctaatatatg ttcaaatcaa gctttaaatg
    10861 ctcttgtagc ttcaatatat atggctacta tgggtaaaga aggatttaaa gaggttggta
    10921 tgcagtctat gaaaaaagca cattatactt acaataagct tgtacaaact ggaaaatata
    10981 agccaatatt taaaggtaag tttttcaaag aatttgctgt acaaggaaat cttaatatag
    11041 aaactataaa tgataagctc ttagaagaaa atatattagg tggttataat ttagaataca
    11101 attatccaga attaaaaaat tcaactttgc tttgtgtgac tgagaaaaga agcaaagagg
    11161 aaatagataa gttagttgga ataatggagg gattataatg aaagaataca atagtttgtt
    11221 gatagatata tctaaaaaag gtaggaaagc atactcactt ccaaagttag atatagatga
    11281 tataaaaata gaagatatga ttgaccaaga tatggcaaga caaagtgagt tgaatttgcc
    11341 agaagttggt gaattagaat tagttagaca ttatacatta ttatcaaata aaaactttgg
    11401 agttgataca ggtttttatc ctttgggttc ttgtactatg aaatataatc ctaaaataaa
    11461 tgaagatatg gcagcacttc caaactttac tggaatgcat ccataccaat cttcggatac
    11521 agctcaaggt tctctttctt tgatgtatga tttatcaaga agacttgcag aaattacagg
    11581 tatggatgaa gttacactac agccttcagc aggttctcat ggtgagttta cagggcttat
    11641 gattataaaa gcatatcatg aaaatagagg tgaccataag agaactaaag tgataattcc
    11701 agattctgca catggaacaa atccagcaag tgcagctatg gcaaactttg atgtgattca
    11761 aatagcatct gataaaaatg gagctgtaga cataaatgca ttaaaagagg ttttgaatga
    11821 tgaagtagca gctcttatgc ttactaatcc aagtactctt ggtttatttg aaaaaaatat
    11881 aaaagaaata gctactcttg tacatgaagc aggaggactt ttgtactatg atggtgcaaa
    11941 catgaatgct attatgggga taacaagacc tggagatatg gggtttgatg tggttcatct
    12001 taatcttcat aagacttttt caactcctca tggaggtgga ggtccaggag ctggtcctgt
    12061 tggagttaaa aaagaattag tacctttttt accaatacca ttaattgaaa gaaaagaaga
    12121 taagtatgta ctaaattatg atagagaaaa atctattggg aaaattaaaa atttctatgg
    12181 taattttgga gttcttgtaa gagcttacac atatatacta actatgggaa gggatggact
    12241 taaagaggct agtgaaatgg cagttttaaa tgctaattat ataaaggaaa gtataaaaga
    12301 tgattatatt ttgccaatag ataccttgtg taagcatgag tttgtattag gtggattgcc
    12361 aagaggagag gccaatataa aaactatcga tattgcaaaa agactactag attatggata
    12421 ccatcctcca acaatgtact ttcctcttat tataaatgag gcacttatga tagaacctac
    12481 agaaagtgag agtatagaga cattagatag ttttatagaa gctatgaaaa gtgttgctaa
    12541 agaggcaaag gaagaaccag aactattgaa aactgctcca cataatactt tggtcaaaag
    12601 agtagatgat gcaagggcag taaagaaacc tatactaaca tggtcacaaa gataaataat
    12661 taaaaagtag agatttaaag tataaagaga attaaatttg taagaaaaag ctatctaact
    12721 taatccagtt tagatagctt ttttgtatat tagtatgtat ggtattttct atataaagtt
    12781 ttaaattata ttagtgctta tatagaatat tgatatgatg attatgtata gatattaata
    12841 agaattgttg aatttatctt gccttaactt tatttactct tttatcttaa gaaaaactta
    12901 actaaaatat agcgaaa
//
LOCUS       DAMJYN010000098        12327 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.102, whole genome shotgun sequence.
ACCESSION   DAMJYN010000098 DAMJYN010000000
VERSION     DAMJYN010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12327)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12327)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12327
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.102"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            228..1157
                     /gene="glsA"
                     /locus_tag="PC466_003122"
     CDS             228..1157
                     /gene="glsA"
                     /locus_tag="PC466_003122"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HDF2770482.1"
                     /translation="MNTLDETLLKEIISSNKKYTNYGQVASYIPELKNARRNDLGICI
                     IDSENNLYSAGNCSTKFTIQSISKPIVLAMALMDNDWEDVFSNVGMEPSGDPFNSIMK
                     LEINDTKKPCNPMINAGAIVTTSLINGSCLEEKEERMLSFFRKLAKNDNIGINYDVYK
                     SEKMTGDRNRAMAYLLKSDGFIRGNVEDVLDLYFKQCSIEIDSVDLARIGINLANYGV
                     DIENGEHLMSEMVSRIVKTFMMTCGMYDASGEFAIKVGIPAKSGVGGGIMASVPGRMG
                     IGVYGPALDKKGNSVAGVKVLEELSNKLKLNIF"
     gene            1255..1818
                     /locus_tag="PC466_003123"
     CDS             1255..1818
                     /locus_tag="PC466_003123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2770483.1"
                     /translation="MKEVLVLRDLECIKAIAHPRRIDILKAFDKSPLSAKQLSQLLEE
                     PHAKINYHIKMLYKVGILELVEEKIKSGIVEKYYYPSAKNVVIGNRILNFSLDNGEEK
                     EELYISKFENMSEVFYKAAEEDVLENENIVDYHDISLTHDELVELSDTMKSKIDEILN
                     KRQHNVEGSKYDIAMVIVPTLEEECPS"
     gene            2306..3142
                     /locus_tag="PC466_003124"
     CDS             2306..3142
                     /locus_tag="PC466_003124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HDF2770484.1"
                     /translation="MIKLGTHLSIAKGFANAAETAVYIGANTFQFFSRNPRGGNAKEF
                     DEKDIIKFQEIRKENNFAPLLAHAPYTMNLGGTKDDVYEFATRVIDEDIRRMDSLGIE
                     YMCFHPGSHIGGGVDFGIDRIVKGLNNAIKGDENITILLETMSGKGTEIGFKFEQLKS
                     IIDKIEHKEKIGVCLDTCHIFSAGYDIVNDLDGVLEEFDKVIGIERLKTVHLNDSMMP
                     FGDKKDRHAPIGEGKIGLKALIDFMEHPSLKHLPFFLETPFDDEGHKRELKMIKEILS
                     SK"
     gene            3394..4389
                     /locus_tag="PC466_003125"
     CDS             3394..4389
                     /locus_tag="PC466_003125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HDF2770485.1"
                     /translation="MRNLGNTNMKIKRVGFGGIPIQRITQDDTNLVINELEKQGINFI
                     DSARGYTISEEAIGIAIEGKRNKFFLATKSMSRDYDSMKRDVEISLNNFKTDFIDLYQ
                     FHNVKEEEYDNLFKDKMAYSALLEAKEQGKIKHIGITSHNLNTIEKAIEDGKFDTIQF
                     PYNIVEGQADEVFKKAHEKGIGIIVMKPLAGGALDNATLAIKYILSKDYIDVVIPGME
                     SVEQVRQNVAVLENLVLDEKDNKEIEEIRNSLGKKFCRRCEYCMPCAVGINIPLSFLC
                     EGYYTRYGLKEWAKEKYEVMDVKPTECIDCGLCESRCPYELPIREMLKTVVEKLG"
     gene            complement(4646..5050)
                     /locus_tag="PC466_003126"
     CDS             complement(4646..5050)
                     /locus_tag="PC466_003126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HDF2770486.1"
                     /translation="MIKITIPGRPISKSNFKLHNINGQAWMPSKGKYSKYLAYENMIA
                     GFINQQYQGETVEENLITVLKLFFPNKRMGDLHNYPKSICDGIEKSGIIKNDKQLKPV
                     FLFDFIDKDNPRVEIELYPVSKYDISYNIFEK"
     gene            6050..6964
                     /gene="queG"
                     /locus_tag="PC466_003127"
     CDS             6050..6964
                     /gene="queG"
                     /locus_tag="PC466_003127"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HDF2770487.1"
                     /translation="MDNKELKAFCNLIGLNCVGVAGVDKYDNLEKILKDRQQKGYLTG
                     MEEPIIENRINPRHIMKDANSIIVCAFPYHINRQEKNKNSNLSKYCHGKDYHIVVKDF
                     LQQICDYISKTVTDFKYKLFVDNGPLVDRYLAYLSGIGYFGINNNIITDEYGSYVFIG
                     YIVNNYKFEEDKPLEKSCFKCGKCVKYCPGNAILGNYDMNPKKCLSYITQKKGDLSEK
                     EKVVLKNGKKVFGCDICQEVCPHNVEMPTTHILEFKENIIDYLDYDEIQNISNKEFKR
                     RYGDRAFSWRGRNIIKRNMEIILDKYDD"
     gene            7070..9307
                     /locus_tag="PC466_003128"
     CDS             7070..9307
                     /locus_tag="PC466_003128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF2770488.1"
                     /translation="MKYNNTSEINPLDYILGQERAVEAMELGLKINNPAYNIYIAGEP
                     GTGKSTYALKVLNEYASKKNTHKDWCYIYNFENPREPIIVELEKGFGRELKKDMEKLI
                     ESLLEDFKNAFESENFEIEKNRLLDEYEIEKDMLLKQIKKYGEEKGFKLKQSKMGIVF
                     IPLKEEEDESDKSDEEFYKAKRELENMAIQVVYKIRNLEEIAEKAVLELEEEIAKLVV
                     EPHIKRLCEKYENYDKIQTYLENIKKDIIEYMYLFYLDEEELKDKYDKEHFIKYKINL
                     FVDNESSKNKESAPVVVEINPSPANLFGKAEYDYANGNIKTDFTKLLSGAFHRANGGY
                     LVLYADQLLKYTMSWEILKKTLQTKKVILETQTAIKPENMPLDVKLVLIGSHYIYDIL
                     YRYDEDFEKYFKVFVDFDSEMDKNEDNEEGIARFIAYQCDKNNLRHFTKSAVEEVIKF
                     STRLSGDLEKLSTKFNKIMEVVIEGSAYAEFRNSEYTEQCDVKKAISEKRKRINRVET
                     HMDESIENGFTLIETEGRKVGVINGLSVLSTGEYSFGRASRITATTSPGSKGIVNIER
                     EVNMSGSIHNKGVLILGGYLSENFAQDLLLSLNAYVCFEQNYGGIDGDSASSAELYVL
                     LSSLSGVSIKQNIAVTGSINQKGDIQVVGGISEKIEGFYSICKTKGLNGEQGVIIPRK
                     NQRNLVLSDEVNDAVRDGKFKIYTVERVEEAIEILTDVKFEEIKKLVKEKLISFSKIQ
                     TVSKE"
     gene            9504..10556
                     /gene="nth"
                     /locus_tag="PC466_003129"
     CDS             9504..10556
                     /gene="nth"
                     /locus_tag="PC466_003129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HDF2770489.1"
                     /translation="MKNVNLKEINEKDVIVEEDINLKGMDKKDVIEKEEVNKKSIDKK
                     DIIEKEEIDKKNVKKVEVQKEIDKMISKKDEIIDEKDIENFRYIEEDKKSIKVSKKST
                     KKGETEKKTKKSSSNKATQKQSKEVKSKSKIKSESANKKDVNKILDELEKLYPDAKCE
                     LNYGTAFELLIATILSAQCTDVRVNKVTSELFKKYNTARDFANLSIEEISKEIKSCGL
                     YKSKSQKIKDTSEQLCELYDGEVPDSLEKLIKLPGVGRKTAGVVLSNAFNHPAIAVDT
                     HVFRVSNRIGIVDEPNPQKTEFALMEAIPKERWSHSHHVLIFHGRRMCKARNPECASC
                     PIKEDCNYYKELNETK"
     gene            10750..11220
                     /gene="trmL"
                     /locus_tag="PC466_003130"
     CDS             10750..11220
                     /gene="trmL"
                     /locus_tag="PC466_003130"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HDF2770490.1"
                     /translation="MSLNIVLVEPEIPQNTGNIIRTCAATGSTLHLVKPLGFSLDDKH
                     LKRCGLDYWDIADIQYYDSFEELQEKYPNSKYFFSTTKAKQSHSDVKYEENCFIVFGK
                     ETKGLPEPLLKANMDTCIRVPMLDVEKARSLNLSNSVAIVVYEALRQIGYPNMR"
     gene            11256..12104
                     /locus_tag="PC466_003131"
     CDS             11256..12104
                     /locus_tag="PC466_003131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HDF2770491.1"
                     /translation="MKNLKIICDSLSDVPKDLLDKYDIDIVSLTVILEEREYKDRIDI
                     SGDEFYKRLREENVYPKTSQATYAQFKEIFEKYTNEDREILYIAGSATATGTYQSAVM
                     AKNDVDGKIYTYDSNLLCMGTGLLVIKAGELASEGKSVDEILPVLDELKEKAFVIFSV
                     DTLEYLQKGGRISSTKAAIGSILNIKPILEIRDGLVSQISQVRGKKNVISKMMELIKS
                     NCGDDLSDQIVYIGYSDDFKEKEQLSKVMQDELRPKEIRFFQIGVCIGAHAGPGVTGI
                     ICLKNK"
BASE COUNT         5058 a         1128 c         2293 g         3848 t
ORIGIN      
        1 gttaggttag aaatttttga cgttataaga atttaaatta ctggattatt agattactaa
       61 attactagat tattaaatta ttaagctatt taaactgttt aaattgtttg aaaaatgaat
      121 tgattcttgt agaaaatagt tttaaagtat aatttttttt aacactgttt tattatagta
      181 caaacttgtg ctaaaataga atatataaca taatataaga ggtgcatatg aatacgttag
      241 atgagacatt attaaaagaa attataagtt ctaataagaa gtatactaat tatgggcaag
      301 tcgctagtta cataccagaa ttaaaaaacg ctagaagaaa tgatttagga atttgtatca
      361 tagatagcga aaataatctt tatagtgctg gaaactgtag cacaaagttt actatacaaa
      421 gtatttcaaa accaattgtg cttgctatgg cacttatgga taatgattgg gaagacgttt
      481 tttcaaacgt tggaatggag ccaagtgggg acccatttaa ttcaataatg aaacttgaaa
      541 ttaatgacac aaaaaaaccc tgtaatccaa tgataaatgc aggggctata gtaactactt
      601 cccttataaa tgggagttgt ttagaagaaa aagaagaaag aatgcttagt ttctttagaa
      661 agttagcaaa aaatgataat ataggaataa actatgatgt ctataagtct gaaaaaatga
      721 ctggagatag aaacagagct atggcttact tattgaaaag tgatggattt atcagaggga
      781 atgtagaaga tgttctagac ctttatttta aacaatgctc aattgagata gattctgtag
      841 atttagcgag aattggaata aatcttgcaa attatggagt agatatagaa aatggtgagc
      901 atttaatgag tgaaatggtt tctaggattg tcaagacatt tatgatgact tgtggaatgt
      961 atgatgcttc tggggaattt gctattaaag ttggcattcc tgcaaaatct ggagttgggg
     1021 gtggtataat ggcttctgtg ccgggacgca tggggattgg tgtttatgga cctgcgcttg
     1081 acaaaaaagg taacagcgtc gcaggagtta aagttttaga ggagttgtca aataaactca
     1141 aattaaatat tttttaaaat attaagaaag gatttttttg acaacaacat ataatttaat
     1201 atataattaa attgtaaaga aatatgaatt aaataaattt tttaggaggg gtcaatgaaa
     1261 gaggtattgg tattacgaga tttggagtgc ataaaggcta ttgcgcatcc acgtagaata
     1321 gatattctaa aagcatttga caaatcgcca ttgtcagcaa aacaattatc tcaattattg
     1381 gaagaacctc atgcaaaaat aaactaccat ataaaaatgt tatacaaagt tggtatttta
     1441 gaattagttg aggaaaaaat aaagtcgggg attgtggaaa agtactatta tccaagtgca
     1501 aaaaatgtgg ttatagggaa taggatactt aatttttctt tagacaatgg ggaagaaaaa
     1561 gaagaattgt acatatcaaa atttgaaaat atgagtgaag ttttttataa ggcagcagag
     1621 gaagatgttt tagaaaatga aaatatagtt gattatcatg atatttctct tactcatgat
     1681 gaattagttg aacttagtga cactatgaag tcaaagatag atgaaatttt aaataaaaga
     1741 caacacaatg ttgaaggttc taagtatgat atagctatgg ttatagttcc tactcttgag
     1801 gaggaatgtc ctagttagag aattaattat ggattaatta aagatataat attagagatt
     1861 gaacatcaaa atttacttaa taatcaaaaa atagtttttg gtatgggtaa aacaatgatt
     1921 tttaatctct atttttttgt tttcttatac ctattgtatt tgtaaataat atgtatagtg
     1981 taagatgtat acactatctg agaagtgctt agataatata caaagtatgt aagattataa
     2041 tatttgaaat tgattaaaat gggtataatt aaagtgtaaa tattaaaatt aaaaattaat
     2101 ataaattaaa tcaatgctag aaatatgtta aaagaggaat gagattagtt gggatagaac
     2161 atcccttaga gcttatgaat ttttagtgaa aaagtactat caaataggaa tctccatctt
     2221 catatgttgg ctaaatatag ttaaggtgga gtagttcaaa attaaaattg agtacaagtc
     2281 gtagtacaaa taaaaggaga ttaatatgat taaattagga acacatcttt caatagcaaa
     2341 aggatttgct aatgcggctg agacagctgt atatattggt gcaaatacat ttcaattttt
     2401 tagtagaaat ccaagaggag gaaatgctaa agaatttgat gaaaaagata taattaaatt
     2461 tcaagaaatt agaaaagaaa ataattttgc accactgctt gcacatgcac catatactat
     2521 gaatctgggt ggtacaaagg atgatgtata cgaatttgca acaagggtga tagatgagga
     2581 tataagaagg atggactcat taggaattga atacatgtgt tttcatcctg gaagtcatat
     2641 aggtggtggt gtagattttg gtatagatag aatagtaaaa ggattgaaca atgccataaa
     2701 gggtgatgaa aatataacta tacttcttga aactatgtcg ggaaagggaa ctgaaatagg
     2761 ttttaaattt gagcaattaa aaagtataat agacaaaatt gagcataaag aaaaaatagg
     2821 tgtgtgtctt gatacatgtc atattttttc agccggttat gatatagtga atgatttaga
     2881 tggggttttg gaagaatttg ataaggttat aggcatagaa agattgaaaa ctgtccatct
     2941 aaatgatagt atgatgccat ttggagacaa aaaagacaga catgctccta taggggaagg
     3001 aaagatagga ttaaaagcat taattgattt tatggaacat cctagtctaa aacatttacc
     3061 atttttctta gaaactcctt ttgatgatga aggtcacaag agagagctta aaatgataaa
     3121 agaaatacta tctagtaaat aaacctttat taaaaatatg tgaaatactc cgccctcaac
     3181 ataattaagg tggagataca atcatgaaat gtgataattt aaattaatgg ataggaataa
     3241 caaaaattgt atacaaatta actgggtata aagtatgatt atattatgaa tagtatgtaa
     3301 atatattgca aagattctca taatttgttg tataattaaa ggtaacatat ttatattata
     3361 taaaaaatta ttaaaagtta ggtggggaaa gatatgagaa atttaggcaa tactaacatg
     3421 aaaataaaga gagttggctt tgggggcatt ccaatacaaa gaattactca agatgatact
     3481 aacttagtta taaatgagtt agaaaaacaa ggaataaact ttattgacag tgcaagaggg
     3541 tatacaataa gtgaggaagc aatcggaatt gccattgaag gaaaaagaaa taaatttttc
     3601 ttagctacta aaagtatgtc cagagattat gattcaatga agagagatgt tgaaataagt
     3661 ttaaataatt ttaaaactga ttttatagat ttatatcaat tccataatgt taaagaagag
     3721 gagtatgata atctttttaa agataaaatg gcttatagtg cccttttaga ggcaaaggag
     3781 caaggtaaga taaaacatat tggtataact agtcacaatt taaatactat agaaaaagct
     3841 atagaagatg gaaaatttga cactatacaa ttcccttaca atatagttga aggacaagca
     3901 gatgaagtgt ttaaaaaagc tcatgaaaaa ggaattggga taatagtaat gaaaccttta
     3961 gctggaggtg ctttagacaa tgcaacactg gctattaaat atatactatc taaagattac
     4021 atagatgtag ttataccagg tatggagagt gttgaacagg ttagacaaaa tgtcgctgta
     4081 cttgaaaatc ttgttctaga tgaaaaagat aataaggaaa ttgaagaaat aagaaattct
     4141 ttaggtaaaa aattctgtag aagatgtgaa tattgtatgc cttgtgctgt aggaataaat
     4201 ataccattga gttttttatg tgaaggttat tatactagat atggattaaa agagtgggct
     4261 aaagaaaaat atgaggttat ggatgttaaa cctactgagt gtattgactg tgggctttgc
     4321 gagagtagat gtccatatga acttcctata agagaaatgc ttaagactgt tgttgaaaag
     4381 ctaggataga ttttatttat tgaaatcggt gtattaaatt tactccgatt tctttttatt
     4441 agatgtggtc ttatatacaa atattaaatt tacatagtta tagctattat ataaatttaa
     4501 tatttgttta atacttatta aatatttgct taatgctttt taaaaacatt tgtttgagta
     4561 tagacataac acaattatta ttgttgtatt agtatagttt caaatactgg agtatcaata
     4621 taatgtcgaa taacacataa aatctttatt tttcaaaaat attataggat atatcgtatt
     4681 tagatactgg ataaagttca atttcaaccc tagggttatc tttatctata aaatcaaata
     4741 aaaatactgg cttaagttgt ttatcatttt ttattattcc acttttttca ataccatcac
     4801 aaatactttt tggataatta tgtaaatccc ccattctctt atttggaaag aataatttca
     4861 agactgttat tagattttct tcaacagttt ccccttgata ctgttggttt ataaaacctg
     4921 caatcatgtt ttcgtatgca agatacttag aatattttcc ctttgaaggc atccatgctt
     4981 gaccatttat gttatgaagc ttaaaattag atttactaat aggtctacct ggaattgtta
     5041 ttttaatcaa atttttcacc atccttatac agtatttatt ataatctgta tatgatttaa
     5101 aagcaaattg ttatttaaag tgtttttaca gggcttgttt gtaaaatttt ccactttaga
     5161 tgtagtaata taagataagt attttgctta caaattttaa aatttgatat atgatggaca
     5221 tattcatatt agactattat aagaccttca taatattaat aagtataggt ttagtaaaga
     5281 gagtaaaaag aaatccatat aagccaagta aagacttaat aaatggcaat gtaaatggga
     5341 tattaattat aagaaaaaat caatcttttt gcattaacta taggaagaat gtcaaaatat
     5401 aactaatgat atttgaagtt ttagagttta tattaaaagg taagaaggtt aagtgggtaa
     5461 aaaaggttga atagattaaa aaggctaagt atctaaaaga gttaagtagg taaaaaagtt
     5521 aaataagtaa atgaaaaaag ctaagtatct aaatgagtta gtagataaaa aaattaaata
     5581 gataaaaaga ttaagtatct aaaagcgtta gtagataaaa aaattaaata gataaaaaga
     5641 ttaagtatct aaaagcgtta gtagataaaa aaattaaata aataaaaaag actaagtatt
     5701 caaaagagtt agtaggtaaa ataattaaat agataaaaag actaagtatt taaaggagtt
     5761 aagcagataa aaaagttaaa taagtaaatg aaaaagacga agtatctaaa agagttagta
     5821 aataaaaaag ttaaataagt aaataaaaaa gatgaagtat ctaaaagagt tagtaggtaa
     5881 aaaactaaat aggtaaaaag acgaagtatc taaaagagtt agtaggtaaa aaagttaaat
     5941 aaataaaaaa gacgaagtat ttaaaagagt tagtagctag aaaaggttaa aaagactaaa
     6001 aaaattaaat aaatttaaaa agtcaattag attaaaaagg aataatttta tggataataa
     6061 ggaattaaaa gcattttgta atttaatagg attaaactgt gtaggagtag caggggtaga
     6121 taagtatgat aatttagaaa agatacttaa ggacagacaa caaaaaggtt atttaactgg
     6181 tatggaagaa ccaataattg agaacagaat taacccaaga catataatga aggatgctaa
     6241 ctctataata gtctgtgcat ttccatatca tataaataga caagaaaaga ataaaaattc
     6301 aaatttatca aaatattgtc atggaaagga ttatcacatt gtagtaaagg actttttaca
     6361 acaaatttgt gattatattt ctaaaacagt aacagatttt aaatacaagt tatttgttga
     6421 taatggacca ttagttgaca ggtatttagc ttatttatca ggaataggat attttggaat
     6481 aaataataat atcataactg atgaatatgg ttcttacgta tttatagggt atatagtaaa
     6541 taattataaa tttgaagaag ataaaccact agaaaaaagt tgttttaaat gtggtaagtg
     6601 tgtaaaatat tgtccgggaa atgctatatt gggaaattat gatatgaacc ccaaaaaatg
     6661 tttatcatat ataactcaaa aaaaaggaga tttgtcagag aaagaaaaag ttgttttaaa
     6721 gaatggcaaa aaggtatttg gatgcgatat ttgtcaagaa gtatgtccac ataatgttga
     6781 aatgccaaca actcatattt tggaatttaa agaaaatata atagattatt tggattatga
     6841 tgagatacaa aatatttcaa ataaagaatt taaaaggaga tatggagata gagcttttag
     6901 ctggagaggg agaaatataa taaagagaaa tatggaaata attttagata agtatgatga
     6961 ctaataataa gagtctgttt catatacttt aatgtgtatt tactttaaca cttgttgtgt
     7021 aaaagtcata ttatatcatt aaagttaaat atggggaggt gggggaatat tgaaatataa
     7081 taatacatct gaaataaatc cactagatta tatattgggt caagaaagag ctgtagaagc
     7141 tatggaatta gggttgaaaa taaataatcc agcgtacaac atatatatag ctggtgaacc
     7201 tggaactggt aaaagtactt atgccttaaa ggttttaaat gaatatgcat ccaaaaaaaa
     7261 tacacataaa gattggtgtt atatatataa ttttgaaaac cctagagagc ctattatagt
     7321 tgaattagaa aaggggtttg gaagagaact taagaaagat atggagaaat taattgaaag
     7381 tcttttagaa gattttaaaa atgcgtttga aagtgaaaat tttgaaatag aaaaaaatag
     7441 acttctagat gaatatgaaa tagaaaaaga tatgcttttg aagcaaatta agaaatatgg
     7501 ggaagaaaaa ggatttaaat taaaacagag taaaatggga atagttttta tccctttgaa
     7561 agaagaggaa gatgaaagtg ataagtctga tgaagagttt tacaaagcta aaagagaact
     7621 agaaaatatg gcgatacagg tcgtatataa aattagaaac ttagaagaaa tagctgaaaa
     7681 agcagtgtta gagcttgaag aagagatagc taaacttgta gtagaacctc atatcaagag
     7741 attgtgtgaa aaatatgaaa attatgataa gattcaaact tatctggaaa atataaagaa
     7801 agatataata gaatatatgt atttgttcta tttagatgaa gaggagttaa aagataagta
     7861 tgataaagag cattttatta aatacaaaat taacctattt gtagacaatg aaagctcaaa
     7921 gaataaagaa tcagcacctg ttgtagtaga gataaaccca agtccagcaa atctatttgg
     7981 aaaggcagag tatgattatg caaatggaaa tataaagact gatttcacaa aactattatc
     8041 aggagcattt catagggcta atggtggtta tttagtactt tatgcagacc aattactaaa
     8101 atatacaatg tcttgggaaa ttcttaaaaa gactttgcag actaaaaaag taatattgga
     8161 aacacaaaca gcaattaaac cagaaaatat gccattggat gttaaattag tactgattgg
     8221 aagccactat atatatgata ttttatatag atatgatgaa gattttgaaa aatattttaa
     8281 agtatttgta gactttgata gtgaaatgga taaaaatgaa gataatgaag aaggaatagc
     8341 aagatttata gcataccaat gtgataagaa taatttaagg cattttacta aatcagcagt
     8401 tgaagaggtt attaaattta gcactagatt atctggtgat ttagaaaaac tatcaactaa
     8461 gtttaataaa ataatggaag ttgtaataga aggaagtgct tatgcagagt ttagaaattc
     8521 ggagtataca gagcagtgtg atgttaaaaa agcaataagt gaaaagagaa aaagaatcaa
     8581 tagagtggaa acacatatgg atgaatcaat tgaaaatgga tttactctaa tagaaacaga
     8641 gggaagaaaa gtaggagtga taaatggtct gtcagtctta agtacaggag aatactcttt
     8701 tggtagagct tcaaggatta cagcgaccac tagcccagga agtaaaggca tagtaaatat
     8761 agaaagagaa gtaaatatga gtggctctat acataacaaa ggagtgctta tattaggtgg
     8821 ctatctttct gagaattttg cacaggattt actattgtca ctaaacgcat atgtttgttt
     8881 tgaacaaaat tatggtggaa tagatggaga tagtgcatct tctgcagaat tatatgtact
     8941 attatcatct cttagtggag tatcaattaa acaaaatatt gctgttacag gttctataaa
     9001 tcaaaagggt gatatacaag tagttggtgg tataagtgaa aagatagaag gattttattc
     9061 tatatgtaaa actaaagggt taaatggtga gcaaggcgtc ataattccta gaaaaaatca
     9121 aagaaatctc gttttatcag atgaagttaa tgatgcagtg cgagatggaa aatttaagat
     9181 atatactgtt gaaagagtag aagaggctat agagatattg acagatgtta aatttgaaga
     9241 aataaagaaa ttggtaaaag aaaaattaat atctttcagc aagatacaaa ctgtgtcaaa
     9301 agaataagtt tattatagaa tttaatgggt atttatgtat aataaaaagc aagaacttta
     9361 ataggttttt gctttttttg taaatatata taaattaaat tcttattttg tatgttttat
     9421 atattgatgt ttattttttg ttgatatgac taaactattt ataaatagtg ttttataaat
     9481 tggtatttta aagggggata attatgaaaa atgtaaatct aaaagagata aatgaaaaag
     9541 atgtaattgt ggaagaagat ataaatctaa aaggaatgga taagaaagat gtaattgaga
     9601 aggaagaagt aaataaaaaa agtatagata agaaagatat aattgagaaa gaagagatag
     9661 ataaaaaaaa tgtaaagaag gttgaggttc aaaaagaaat agataaaatg attagtaaaa
     9721 aagatgagat aattgatgag aaagatatag agaattttag gtatattgaa gaagataaaa
     9781 aaagtatcaa agtaagtaaa aaaagtacta aaaaaggtga aacggagaaa aaaacaaaga
     9841 aaagtagttc taataaggct acacaaaaac aaagcaaaga agttaaaagt aagtctaaaa
     9901 ttaaaagtga atcagccaat aaaaaagatg taaataagat tttagatgag ttggaaaaat
     9961 tgtacccaga tgctaaatgt gagttaaatt atgggacagc ctttgaactt ttaatagcaa
    10021 ctattttatc agcacaatgt actgatgtaa gagtgaataa agttacttca gagttgttta
    10081 aaaagtacaa cacagctaga gactttgcta atttgagcat tgaagaaatt agtaaagaga
    10141 taaagagttg tggtctttac aaaagcaagt ctcaaaaaat aaaggataca tctgaacagc
    10201 tatgtgaatt atatgatggt gaagtacctg atagcttaga aaagcttata aaattacctg
    10261 gtgttggaag aaaaacggca ggggttgtac ttagtaacgc ttttaatcat ccagcaatag
    10321 ctgtagatac tcatgtattt agagttagca atagaatagg aatagtggac gagccaaatc
    10381 ctcaaaaaac agaatttgca cttatggaag ctataccaaa agaaagatgg tcacactcac
    10441 atcatgtatt aatttttcat ggaagaagaa tgtgtaaagc tagaaatcca gaatgtgcaa
    10501 gttgcccaat aaaagaagat tgtaattatt ataaagaact taatgaaacg aaataacttt
    10561 tagaaagtaa gttgtacaag agggattttc tgatataata atacttgtga aaatgttaga
    10621 taaaaaacta ttatatacat gaaataaaaa ttattattaa cattatttta tataatagta
    10681 taatattatt gttattctgt ttataaaata aaatttgata aataaaagcg atacttaggg
    10741 aggattaaaa tgtcattaaa tatagtatta gtagaaccag aaatacctca aaatacagga
    10801 aatataataa gaacctgtgc agcaacaggt tcaactttac atttagtaaa accactgggt
    10861 ttttcattgg atgataaaca cctaaaaaga tgtgggcttg actattggga tatagctgat
    10921 atacaatatt acgatagctt tgaagaatta caagaaaagt atccaaatag taaatacttt
    10981 ttttctacaa caaaggctaa acagtcacat tcagatgtga aatatgaaga aaattgtttt
    11041 atagtatttg ggaaagaaac aaagggatta ccagaacctt tgttgaaagc aaatatggat
    11101 acttgtatta gagtgcctat gttggatgtt gaaaaggcta ggtcattaaa tttatcaaat
    11161 tcagttgcta ttgtagtgta cgaggcttta agacaaatag gatacccaaa tatgaggtag
    11221 tttcaacaag cctaaatgag aaaggagcat acttaatgaa aaatctaaag ataatctgtg
    11281 acagtttatc ggacgtgcca aaagatttgt tagataaata tgatatagat atagtttcat
    11341 taacagttat actggaggaa agagaataca aggatagaat tgatatatct ggagatgaat
    11401 tttataaaag gcttagagaa gaaaatgtat atccaaaaac ttctcaagct acttatgccc
    11461 aatttaagga aatttttgag aaatatacaa atgaggatag agagatactt tatatagcag
    11521 ggtctgccac agctacaggg acgtatcaaa gtgctgtaat ggcaaagaat gatgtggatg
    11581 gtaaaatata tacatatgac tctaacttgc tttgtatggg aactggttta cttgtaataa
    11641 aagcaggaga acttgcaagt gaaggaaagt ctgttgatga aatattacct gttttggatg
    11701 aattaaaaga gaaggctttt gttatatttt cagtagatac attggaatat ttacaaaagg
    11761 gaggtagaat atcatctact aaggcagcaa taggaagtat attaaatata aaaccgattc
    11821 ttgaaataag agatggacta gtttcgcaaa tatctcaagt aagaggaaag aagaatgtaa
    11881 tttctaagat gatggaattg ataaaatcaa attgtgggga tgatttatca gaccaaattg
    11941 tgtatatagg atatagtgat gattttaagg aaaaagaaca attatctaag gttatgcaag
    12001 atgaattaag acctaaagaa attagatttt tccaaattgg tgtgtgtata ggtgcgcatg
    12061 ctggtcctgg tgtcactggt atcatatgct taaaaaataa ataatatatt tttggatgac
    12121 attatttatt tttttattaa attaggatag aatattaatt attgagatgt taaattggat
    12181 ttattttgga tgaaattaag tgttgatata ttagatttag tttgtaggga agtgtgtaaa
    12241 tagataagaa tctattgcac acttttttat agtaagattt attaaaaaaa tttcaaaatg
    12301 tacttgtaaa ttgtatataa aaaaatt
//
LOCUS       DAMJYN010000099        12166 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.103, whole genome shotgun sequence.
ACCESSION   DAMJYN010000099 DAMJYN010000000
VERSION     DAMJYN010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12166)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12166)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12166
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.103"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            373..2466
                     /locus_tag="PC466_003132"
     CDS             373..2466
                     /locus_tag="PC466_003132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDF2770492.1"
                     /translation="MNKRNFEVILNQLQINIYVTNIHTNEIIFMNKKMKEEYNILDPE
                     GKVCWQVLYPEQNSTCSFCKVLELLKNDKKGVLIKWYEKCNKLNRVFENYDSLITWQD
                     GTVVHMHQSIDIANSTILNKPIKINEFNEISNTKEGKGVFNFSRDNFDYNSTLLYDAL
                     IRGTDEYIYICNMKTGVFRYSPSQVELFDLPGEIVENPLIYWKKIVHPEDWNRFYKSN
                     TEIGKNQMDYHTVEFRAKNRSGEYIWLRCRGQLMRDEFGEPSIFAGIMTQLGKQNKID
                     SLTQLLNYHEFMSVFEDKISNPMIEKLCIVLLNIDDFKNVNEMYDRDFGDNIIKTLAQ
                     SIQSILPDNAELYKLDGDEMGILVDNVEENEILTLYNQIQNMIIHLQLWRKYGLNITI
                     SAGCVIYPKHGDTVKELYKCASYSLQYAKEHGKNRLVFFSQEILKNKMYSLEMMRDLK
                     ASINDDFRGFSLRFQPQVDTQSHKIIGVEVLLRWTNDKCKAISPLEFIPILEENDMIN
                     IVGAWVLRMALRTFRKWIDYYPFFKVSVNVSAVQILEDTFIEDIVKIIDDENFPYQNL
                     VLELTESHTVQNMSILQFKFKALQDLGIYIAMDDFGTGYSSLEVLKFSPIDIVKIDRV
                     FVKDILKSKFDATFIHFIVAICHDVGIKVCLEGVETQEEYDLVKQIKPDYIQGYLFGK
                     PQTATEIFDLLKLDN"
     repeat_region   3127..3420
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=3127..3155
                     /rpt_unit_seq="gttttatattaactatatggaatgtaaat"
     gene            complement(3588..3872)
                     /locus_tag="PC466_003133"
     CDS             complement(3588..3872)
                     /locus_tag="PC466_003133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770493.1"
                     /translation="MLVRVKIVIGATIRYLIKHKVNYCNKKSLDKLELKYGNIDREKA
                     VKLEIFYQYLIELEYIEMSLLIRRLDTAITSLALVSIITIASYYLIRKNV"
     gene            4079..4897
                     /locus_tag="PC466_003134"
     CDS             4079..4897
                     /locus_tag="PC466_003134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF2770494.1"
                     /translation="MEKQYFTTGEFAKLCGISKQTLIFYDKIGIFSPEYKDKNNYRYY
                     SVYQYDTLDILQSLREIGMSLEEIKEYIQNRTPQLCVKMLKEEEKKIREKIKKLRKIS
                     SKMQNRINITVEGISKMNSEEIYISKKFEEYLVLSSDLSNMSNSDFMMELIDFTNYCK
                     SKNLYQGYELGVIVSNENIKNGDYLSISSFYLKIDKKIKDKKLYVKPEGMYACIKHIG
                     KYEDSYKSYEKLKKYIYENEYKIIGNSYEESILDFFCESNEDNYMTEISIQVSR"
     gene            complement(5030..7150)
                     /gene="feoB"
                     /locus_tag="PC466_003135"
     CDS             complement(5030..7150)
                     /gene="feoB"
                     /locus_tag="PC466_003135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HDF2770495.1"
                     /translation="MGLTHNSTKMSSLKDMFDIDNKEDQFVIALAGNPNTGKSTVFNH
                     LTGLRQHTGNWPGKTVATARGNFKYKNTEYALIDLPGTYSLFALSQEEIVARDFICFG
                     NPDAVIVVCDATCLERNLNLVFQVMELTDKVILCINLIDEARKKGITIDKKLLEDSLG
                     IPVILTAARNGSGMDELLDTLNDVSFDKYKLNNKPVRYNENIENVVKSIQPELDNIIP
                     GINSRWLGLRLIDGDESIFESMSNYIDKDSIDAINEVKKKIPDNINKQKIRDEFTKIN
                     YDYAKKLSDECCSNVAKKSTDREEKVDKILTSKIFGLPIMLLLLGTILWITIEGANYP
                     STLLSNLLLGFEPSISGILNSINCPSWLNDMLVLGLYRTLAWVISVMLPPMAIFFPLF
                     TLLEDFGYLPRVAFNLDHLFKKACAHGKQCLTMCMGFGCNAAGVIGCRIIDSPRERLI
                     AILTNNFVPCNGRFPTLIAISTIFFSSVITNSFVSSVATALCITLLIILGVIITLLVS
                     YTLSKTLLKGVPSTFTLELPPYRVPQIGRTLYTSIIDRTIFVLGRAVMVAIPAGVITW
                     IFANIYIGDLSILSHVANFLDPLAKLIGLDGFILLAFILGFPANEIVVPILLMAYLAT
                     GSMIELDSFSALGQVLREHGWTYLTALNVMLFSLLHWPCATTLLTIKKETGSLKWTAL
                     GFLMPTILAFVVCFLTTTVYNLFI"
     gene            complement(7176..7403)
                     /locus_tag="PC466_003136"
     CDS             complement(7176..7403)
                     /locus_tag="PC466_003136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HDF2770496.1"
                     /translation="MKNLNDIQVKKTVKVEDILSSGNLRERMLALGLTRGAVIDVVRK
                     GPKNNLTVYKIRGSKIALRQEESSLILVSDI"
     gene            complement(7730..8170)
                     /locus_tag="PC466_003137"
     CDS             complement(7730..8170)
                     /locus_tag="PC466_003137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2770497.1"
                     /translation="MFKIKHFNDLSLDEFYEIAKSRYEVFACEQKIFSLNDYDDIDKS
                     SYHIFLKENGLICAYARIIPKEYSSYNDVSIGRVLVLSSHRRKGLAKQMMDCAIDFIK
                     INLHENNITLSAQTYIKNLYLSCGFKEISEVYDEAGIEHIKMRL"
     gene            8322..9311
                     /locus_tag="PC466_003138"
     CDS             8322..9311
                     /locus_tag="PC466_003138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2232 domain-containing protein"
                     /protein_id="HDF2770498.1"
                     /translation="MIYGGSVLNTTKKLTEAALLSSLFIVVTIIAVSTGFGYAIYLDF
                     IVPVFFCIICLKCDLKYTILSGITSLLIISLVLGNLGTAIWASQSVLLGIMCGYLINK
                     PTMVMDDLVYGSVFGVIVMVFIDIYASTLIGYSFMKEFQGYSKWIYFNGYTNFIYYLM
                     IALFPFGMVFCIYLLSLILGNKLHILDSNSLKKFLIFKNFRSLNQFLCCSKKAFYICV
                     SYLAIFEVLKLLNVKVDSVYLKTIFISITYISVYFIIRDSCMSLQNFIIAKFRKLLYA
                     RILFLIIILLLFFIFDVTVISLIIINAFLNKKINIRLSQSNIVNKQINLLIEK"
     misc_binding    9463..9715
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            9787..10995
                     /locus_tag="PC466_003139"
     CDS             9787..10995
                     /locus_tag="PC466_003139"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HDF2770499.1"
                     /translation="MKSIDEQMRIIMKGVDDLIDEKELREKLIKSEKEGKPMIVKLGL
                     DPSAPDIHLGHTVVLRKMKQLQDLGHQIVIIIGDFTGKIGDPTGKSKARKALTTEQVL
                     ANAKTYEEQIFKVLDKEKTIVRFNSEWLAKLNFEDVIKLAATITVARMLEREDFKKRY
                     EGQMPISVHEFFYPLMQAYDSIALEADIELGGTDQRFNLLMGRSLQREFGMESQIVIM
                     MPLIEGLDGKEKMSKSLGNYIGIDEEAGIMYQKSMEIPDELIIKYYNLVTDVHPDEVN
                     KIESQLKEGSVNPRDIKMNLAREIVTLYHGEESAKEAEERFKSVFQKGQIPEDIQTIQ
                     VKEDGFDLIEVLVSNEIVKSKSEVRRLASQGGVKVNGEKVEDLSTIVKESELVVQIGK
                     KKFVKIELVK"
     gene            complement(11056..11937)
                     /locus_tag="PC466_003140"
     CDS             complement(11056..11937)
                     /locus_tag="PC466_003140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase"
                     /protein_id="HDF2770500.1"
                     /translation="MVKKRKKKTVTLTILVVIVIGIFSMAWADMSRKKEMKETQERLK
                     AERLEKERIEKEKNEPIIGAKKEAVKEYGYDAKIVWDKLNKYDYSNNGEKIVFLTFDD
                     GPSTTNTPQVLDILKRHGVRGTFFIKGDSLERKGANEILKRTFDEGNAIAHHSYTHDY
                     KKLYPGRSLNLDTFVNELNKTDEAMKKVLGKNFSSNVVRCPGGYMSWKNMEPLGNYLK
                     EKNMASIDWNALNADAEGKKKNAQELFEHAKKSSEGKEMVVLLMHDTYGKQETVNALD
                     QIITYFKDNGYQFKILI"
BASE COUNT         4628 a         1448 c         1770 g         4320 t
ORIGIN      
        1 agaaaaatta tgatgttttt agaaattaat gctttttaac ttcaatagta tcaataatac
       61 tgatttttta taaaaattta aaacaataat aaaatatata atttattttt gtggacaatt
      121 tgtcaagatt agtaccaagt taaaatttaa tataagagag agatgtatta tgtaatatta
      181 atttttttta aattggtaat actatattgc tgtatttttt tttatcaatt ataatttaaa
      241 atatgaaata ataaactttc taattaaatt aaggtattta gtgtgtatgt ataagttata
      301 agtaaatctt ctaaaaagaa taattttaac agtgttgtta taaagagcag taactatgga
      361 ggagataagt atatgaacaa acgtaatttt gaagttatat taaatcaact acagattaat
      421 atatatgtta caaatattca tactaatgaa attattttta tgaacaagaa aatgaaagaa
      481 gaatataata ttttagatcc agaaggaaaa gtttgctggc aagtattata tcctgagcaa
      541 aattctactt gtagtttttg taaagtttta gaactattaa agaatgataa aaaaggagta
      601 ttaataaagt ggtatgaaaa atgtaataag ttaaatcgtg tttttgaaaa ttatgatagt
      661 ttaattacat ggcaagatgg cacagttgtt catatgcatc aatcaataga tattgcaaac
      721 tcaacaatct taaataaacc aattaagatt aatgaattta atgaaatatc aaatactaaa
      781 gaaggaaaag gagtttttaa tttttcaaga gacaattttg attataattc tacattgctt
      841 tatgatgctt tgattagagg tacagatgaa tatatataca tttgtaatat gaaaacaggc
      901 gtatttcgat attcaccatc acaagttgaa ttatttgact taccaggaga aattgttgaa
      961 aatccgctta tttactggaa aaaaattgta catccagaag actggaatcg tttttataag
     1021 tcaaacactg aaataggtaa aaaccagatg gattatcata cagtggaatt tagggctaaa
     1081 aatcgtagtg gagaatatat atggttaaga tgtagaggac aactaatgcg tgatgaattt
     1141 ggagaaccaa gtatttttgc aggaataatg acgcaattag gtaaacaaaa taagattgat
     1201 tcattgacac agttactgaa ttatcatgaa tttatgagtg tatttgaaga taaaatttca
     1261 aatcctatga ttgaaaaatt atgcatagta ttattaaata ttgacgattt taaaaatgtt
     1321 aatgagatgt atgataggga ttttggagat aatataataa aaacactagc acagtctata
     1381 caatctattt taccagataa tgctgaactt tataaacttg atggggacga aatgggtatt
     1441 cttgttgata atgttgaaga aaatgaaatt ctaactctat ataatcaaat acagaatatg
     1501 attatacacc ttcaactatg gagaaaatat ggattaaata taacaatttc tgctggttgt
     1561 gtaatatatc caaaacatgg agatacagta aaagaacttt ataaatgcgc tagttactct
     1621 ttacaatatg cgaaagagca tggtaaaaac aggcttgttt ttttctccca agaaatatta
     1681 aaaaataaaa tgtattcatt agaaatgatg cgggatttaa aggcatcaat taatgatgat
     1741 tttaggggat ttagtcttcg attccagcca caagtagata cacaaagtca taaaataata
     1801 ggtgtagaag ttcttttaag gtggactaat gacaaatgca aagcaatttc tcctttggaa
     1861 tttattccaa tattagaaga aaatgatatg ataaatattg taggggcttg ggtgcttcga
     1921 atggcattac gtacttttag gaaatggatt gattactatc ctttttttaa agtgagtgta
     1981 aacgtttcag ctgttcaaat attagaagac acatttattg aagatatagt aaaaattata
     2041 gatgatgaaa attttcctta tcaaaatctt gttttagaat tgacagaaag tcatacagta
     2101 caaaatatga gtattttaca gtttaaattt aaggctttac aagatttagg aatttatatt
     2161 gctatggatg attttggtac tggatactcg tctctagaag ttttaaaatt ttctccaata
     2221 gatatagtga aaattgatag agtatttgtt aaagatatat taaagagtaa gtttgatgct
     2281 acatttatac attttattgt tgcaatttgt catgatgtag gaataaaagt atgtttagaa
     2341 ggtgtagaaa cacaagaaga gtatgattta gttaaacaaa taaagccaga ttacatacaa
     2401 ggatatttat ttggaaaacc gcagacagca acagaaatct ttgacctttt aaagctagat
     2461 aattaattct aatttatcaa taatatcact gaaaagcttt aaaatcaaaa atacattaaa
     2521 ttattatatt gaagatatat caattataaa ttgcaatata agaaaatagc atttcaaggg
     2581 atgttaaatt aggagtagta tatgattaaa gtattttaaa aagggataac tataataaaa
     2641 atagatatct atttttagat taaaaataat atatcataaa taaaataata agaggtagat
     2701 acagttttaa gggaatacaa aagtttttaa ttaaactatg cttgttcaga tagatattta
     2761 tttaagaaaa aagactatta aaagcaatat acaagaatga tatattagat tgattaaaca
     2821 agcataaata ttatgtaaaa aactttaagt tatagaattt aaatccaatg tagatagatt
     2881 acgttttttc ttgcttttat tatggtataa attggtatca atattcaaaa gtaatatatt
     2941 tatgatataa taaaattata gaaattttgc agtgagctat atttgtgata aaatttggcg
     3001 taacagttga aatataaggt gttgagagtg catgataagc gttatcaatt gcactattgc
     3061 tcgttcactg caaatttagg agagttgtat acgtgtaagt gttgaaaata ctaagtttat
     3121 tttggggttt tatattaact atatggaatg taaatctcgg agaatttcct aatgtggatt
     3181 taataggaag tgttttatat taactatatg gaatgtaaat tttagcaaat ttttcgtaaa
     3241 agtcactatt ttcaatggtt ttatattaac tatatggaat gtaaatacat ataaaacttt
     3301 catcttctgt taattcatta aaacgtttta tattaactat atggaatgta aatccatctt
     3361 ttgttgtttt acataaattt atattactta cgttttatac taactatacg gaatataaat
     3421 ttttataatt ttcttttaat gtgttatctt atgattatct agttatatta gcatacaaaa
     3481 atataataaa attacactat attataaaaa ccaaaaggta gtatagaaat cctattacct
     3541 ttttattatt aattttatca gtgttttatt ataaatagct tacataatta cacatttttt
     3601 ctgattaaat aatatgatgc tattgttata atagatacta atgctaatga tgttattgca
     3661 gtatctaatc ttcttattaa taaactcatt tctatatatt caagttctat taaatattga
     3721 taaaatattt ctagtttaac agctttttct ctatctatat ttccatactt taactctaat
     3781 ttatctaaag attttttatt acaataatta actttatgtt taattaaata tcttattgta
     3841 gcacctatta caattttcac tctaacaagc ataaatataa tattccatcc aaaagttaag
     3901 aggggatatc ttttttatga gaggaatgga taaaatattt ataactgaca tctaactgat
     3961 atttaagctt taaaatcaaa accatattga ttttctaaaa taataactac ttgatttagt
     4021 aaataataaa gaatatagta actatataga caacaaaaag aaaaggagtg tataaccctt
     4081 ggaaaaacag tattttacaa caggtgaatt tgctaaattg tgtggtatat ctaagcagac
     4141 attaattttc tatgacaaaa taggtatttt ttctcctgaa tataaagata aaaataatta
     4201 tagatattac tcagtttatc aatatgatac acttgatata ttacaatcat taagagaaat
     4261 aggaatgagt ttagaggaaa taaaagagta tatacaaaat agaactcccc agctttgtgt
     4321 gaaaatgctt aaagaagaag aaaaaaagat aagagaaaaa ataaaaaaac taagaaagat
     4381 aagctctaag atgcaaaata gaataaatat aacagttgaa ggaatttcta aaatgaatag
     4441 tgaagaaatt tatatatcca aaaagtttga agaatattta gttctatcaa gcgatttgag
     4501 taatatgagt aatagtgatt ttatgatgga attaatagat ttcaccaatt attgtaaatc
     4561 gaaaaatttg tatcaaggat atgagttggg agtaatagta agtaatgaaa atataaaaaa
     4621 tggggactat ttaagtatat caagttttta tttgaagata gataaaaaaa taaaggataa
     4681 aaagctatat gtaaagccag aaggaatgta tgcttgcata aaacatattg gaaaatatga
     4741 ggattcatat aaatcttacg aaaaattgaa aaaatatata tatgaaaatg aatataaaat
     4801 tattggaaat tcgtatgagg agagtatact tgactttttt tgtgaaagta atgaagataa
     4861 ttatatgact gaaatttcaa ttcaagtatc cagataagaa ttaaaataga gatatattca
     4921 aatgttaagt aattttactt atcattgaat atatctctat gctttataat aaagtatata
     4981 aatttttaaa tagtttctct aatatatgtc taatgtcagt taatactaat tatataaata
     5041 aattgtaaac tgtagttgtt aaaaaacaaa caacaaaagc aagtatagta ggcattaaga
     5101 atcctaaggc agtccatttt aaactaccag tttctttttt tattgttaaa agtgttgttg
     5161 cacaaggcca atgcagtaaa ctgaacagca taacatttaa agctgtcaaa taagtccatc
     5221 catgttctct aagaacttga cctaaagcac taaagctatc taattctatc atagaaccag
     5281 ttgctaggta agccattaaa agtataggta caactatctc atttgctggg aatccaagaa
     5341 taaaagcaag taatataaaa ccatcaagac caattaattt agctaaaggg tctaaaaagt
     5401 ttgcaacatg tgataatatg cttaaatctc ctatatatat atttgcaaat atccaagtta
     5461 tgacaccagc aggtatggct accattacag cccttcctaa aacaaatatt gttctatcta
     5521 ttatagaggt atataaagtt cttcctattt gaggaactct ataaggagga agttctaatg
     5581 taaatgtaga cggaactcct tttaatagcg tcttagaaag agtataagaa accaacaatg
     5641 ttattataac acctagaatt atcagtaaag ttatgcaaag tgcagttgct acgcttgata
     5701 cgaaagagtt ggttataact gagctaaaaa atattgtaga tatagctatc aaagtaggaa
     5761 aacgaccatt acaaggaaca aagttgtttg taagtatagc tataagtctt tcccttggag
     5821 agtcaattat cctacaacca ataactccag ctgcattaca tccaaatccc atacacatag
     5881 tcaaacactg ttttccatgt gcacaagctt ttttaaatag gtggtctaag ttaaatgcaa
     5941 ctcttggcaa atatccaaaa tcctcaagta gggtaaataa tggaaaaaat attgccatag
     6001 gaggtagcat tacagagatt acccatgcta atgttctgta taatcctaaa accaacatat
     6061 catttaacca tgatggacaa ttaatactat ttaatatacc cgaaatactt ggctcaaatc
     6121 cgagtaataa attagataat aaagtggatg gatagttagc cccttctata gtaatccaca
     6181 atatagtacc taataataag agcattattg gaagcccaaa tattttagat gttaatattt
     6241 tatctacttt ttcttctcta tcagttgatt ttttagcaac attagaacaa cactcatcac
     6301 tcagtttttt agcataatca tagttgattt tagtaaactc atctcttatt ttctgtttat
     6361 ttatattgtc tggaatcttt ttctttactt cattaatagc atctatagaa tctttgtcta
     6421 tataattact catagattca aatatacttt catcgccatc aataagtcta agtcccaacc
     6481 atctagaatt tatacctggt ataatattat ccaattctgg ttgaattgat tttaccacat
     6541 tctctatatt ttcattgtat ctaacaggtt tattatttaa tttgtatttg tcaaaagata
     6601 catcatttaa agtatccaat agttcatcca taccagagcc atttcttgca gcagttaaaa
     6661 taactggaat accaagagaa tcctctaaaa gttttttatc aatagtaatg cctttttttc
     6721 tagcttcatc tattaaatta atacacaaaa taactttatc tgtaagttcc atcacttgaa
     6781 atactaaatt taaatttctt tcaagacatg tagcatcaca tactactatt actgcatctg
     6841 gattaccaaa acatataaaa tcacgagcta caatttcttc ttgtgataag gcaaataaag
     6901 aatatgttcc tggtaaatct attaatgcat attcggtatt tttatattta aaattaccac
     6961 gagctgtagc tacagttttt cctggccagt ttccagtatg ctgtctaagc cctgtaagat
     7021 gattaaatac agtactttta cctgtatttg gattgccagc caatgcaatt acaaactggt
     7081 cttccttatt gtctatatca aacatatctt ttaaagaact cattttagtt gagttatgtg
     7141 tcaaccccat attaatatcc tcctgctaga aatttttaaa tgtcagaaac taatattaag
     7201 ctactttctt cttgtcgtag agctatctta ctacctctga ttttatagac agttaaatta
     7261 ttttttggac cttttctaac tacatctata acagctcctc tagtaagacc aagcgctaac
     7321 attctttctc ttaaattacc actagataat atatcttcaa ctttgacagt ttttttcact
     7381 tgaatatcgt taaggttttt catagtagca cctccatgct tgaaatttag cctgggctaa
     7441 tcttcttatt ctaaactatg cattatatta ttaccttgtt acttttacaa aaaaaagata
     7501 ggcaagatgc ctatcataca aagttgggta taattcttac ttttggggaa agtagaatat
     7561 agaataaaaa ttaacacttt gaatccatat aattattgaa ttttgataat aaaaaagtca
     7621 gaaagcaaaa gcctcctgac tctatgtaag gtattttcaa atacctaaat atcaattcaa
     7681 tatttaattt atacttaaat tatatattaa caatattagc ttgtcaacac tataatctca
     7741 ttttaatatg ttcaatacct gcttcgtcgt atacttctga gatttcttta aaaccacaag
     7801 ataagtaaag gttctttata taagtttgtg ctgataaggt tatattattt tcgtgtaagt
     7861 taatttttat aaaatctata gcacaatcca tcatttgttt tgctaatcct tttcttctat
     7921 gactagaaag aactaaaact ctaccaatgg aaacatcatt ataagagctg tattctttag
     7981 gaattattct agcataagca caaatcaatc cattttcttt taaaaatatg tgataagagc
     8041 ttttatctat atcatcataa tcgtttaatg aaaatatctt ctgttcacaa gcaaatacct
     8101 catatcttga ttttgctatt tcataaaatt catctaaact caaatcatta aagtgtttaa
     8161 ttttaaacat agtaattacc tcctagcatc ttaaaaaact gaatattaag atacattata
     8221 ccatttttaa cataaatacc tttattaaaa tttatattta ttaaaaatat ttttaaaaag
     8281 tgatatacta tattaaaaac aaaactttag ttagaaaatt tatgatttat ggaggcagtg
     8341 ttttgaatac tactaaaaaa ttaactgaag cagctttatt gtcatcttta ttcatagtag
     8401 taacaattat agctgtgagt actggatttg gatatgctat ttacttagat tttatagtgc
     8461 cagtattttt ttgtataatc tgcttgaaat gtgatttaaa gtataccatt ttatctggaa
     8521 ttacttcact tttaataatt tctctggtac ttggaaatct aggaactgct atttgggcaa
     8581 gtcagagtgt attacttggt ataatgtgtg gctatctaat aaataagcct acaatggtta
     8641 tggatgattt agtatatggt tcagtatttg gggttattgt aatggttttc attgatatat
     8701 atgcttcaac attaataggt tatagtttta tgaaagaatt tcaaggatat agcaaatgga
     8761 tttattttaa tgggtataca aattttattt attatttaat gatagcattg tttccttttg
     8821 gtatggtgtt ttgcatatat ttattaagtt taattttagg gaataaattg catattttag
     8881 attctaattc tttaaaaaaa tttttaatat ttaagaattt tagaagttta aaccaatttt
     8941 tatgttgctc aaaaaaagct ttttacatat gtgtttctta tctagccatt tttgaagttc
     9001 taaaactgtt gaatgttaaa gttgattctg tttatttaaa aacaatcttt atatcaataa
     9061 cctatataag tgtctatttt atcattagag actcatgtat gtcactacaa aactttataa
     9121 tagctaagtt tagaaaatta ttatatgcta gaattttatt tttgataata attttattgc
     9181 tgttttttat atttgatgta acagttatta gtttaataat tataaacgca tttttaaata
     9241 agaaaataaa tataagattg agtcagagta atatagtcaa taaacaaata aatcttttga
     9301 ttgaaaaata aactttgggt attggtaaaa aatataaaaa agtagtataa tgtaaaaaaa
     9361 catgtatata ataataaaaa aggttgacaa aatataaaaa taataatata ttatgagtaa
     9421 gttaagaaaa atttcttgta attgatgaaa taatctgaat atataaatgc tatgaagaga
     9481 agaagtaggg ctagatttta tttaacagag agttccagtt tggtgaaatg gaataaattg
     9541 atttagtttg aatacatctc agagcactat ctctgaaaga taacaaccat taagagatat
     9601 cggattagta cacgttatag tacacgagta tatgtaattg tactctaaga gattaatatc
     9661 gtgagatatt gatgaactaa ggtggtaaca cgtaagcaat gctttcgtcc ttttaagagg
     9721 atgaaagctt tttttattat aaaaaaaaaa ttatagatta tataaatatt ttaggaggaa
     9781 tgaaaaatga aatcgataga cgagcaaatg cgaataatta tgaaaggtgt agatgattta
     9841 atagatgaga aagagttaag ggaaaagctt attaaatcag aaaaagaagg aaagcctatg
     9901 atagtaaaat tgggtctaga cccaagtgct ccagatatac atttagggca tacagtagtt
     9961 cttagaaaga tgaaacaatt acaagattta ggtcatcaaa tagtaataat aattggagat
    10021 tttacaggaa aaattggaga cccaactgga aaatctaaag ctagaaaagc tttaacaaca
    10081 gagcaagttc ttgcaaatgc aaaaacttat gaagaacaaa ttttcaaagt tttagataaa
    10141 gaaaaaacta ttgtaagatt taatagcgag tggttagcca agttaaattt tgaagatgta
    10201 ataaaattag cagcaactat tactgttgcg agaatgttag aaagagaaga ttttaaaaag
    10261 agatatgaag gacaaatgcc aatatcagta catgagttct tctacccatt aatgcaagca
    10321 tatgactcta tagcattaga agctgatata gaacttggtg gaactgacca aagattcaat
    10381 ttactaatgg gaagatcatt acaaagagaa tttggtatgg agtctcaaat agtaataatg
    10441 atgcctttaa tagaaggatt agatggtaaa gaaaaaatga gtaagagttt aggtaactat
    10501 attggaatag atgaagaagc gggaataatg taccaaaaat ctatggaaat tcctgatgaa
    10561 cttataatta aatactacaa tttagtgaca gatgttcatc ctgatgaagt taataaaata
    10621 gaatctcagt tgaaagaggg ttcagtaaat ccaagagata taaagatgaa cttagcaaga
    10681 gaaatagtaa cattatacca tggagaagaa tctgctaaag aagctgaaga aagatttaaa
    10741 tctgtattcc aaaaaggtca aatacctgaa gatatacaaa caattcaagt taaggaagat
    10801 ggatttgact taatcgaagt actagtttct aatgagattg ttaagagtaa gagtgaagtt
    10861 agaagattag cttctcaagg tggagtaaag gtaaatggtg aaaaagtaga ggatttaagc
    10921 actattgtaa aagagagtga attagttgtt caaataggaa agaaaaaatt tgtaaaaatc
    10981 gagctagtaa aatagagtaa agtaaaagca agtctattga gtataaaatg tacattcaat
    11041 aaacttgctt ttttattata ttaaaatttt aaattgataa ccattgtctt taaaatatgt
    11101 tataatttgg tccaatgcat ttactgtttc ttgttttcca taagtatcat gcattaaaag
    11161 aacaaccatt tctttgcctt cagaagattt ctttgcatgt tcaaataatt cttgtgcatt
    11221 tttcttttta ccttctgcat cagcatttaa agcgttccaa tcaattgatg ccatgttttt
    11281 ctcttttaag tagtttccta gaggttccat atttttccat gacatatacc cgcctgggca
    11341 tctaactaca tttgaggaaa aattctttcc taagactttt ttcatagctt catcagtttt
    11401 gttaagttca tttacgaatg tatcgagatt taggcttctg ccaggatata gttttttata
    11461 gtcatgggta taagagtgat gggctattgc atttccttcg tcaaatgttc tttttaaaat
    11521 ttcattagct ccttttcttt caagagaatc acccttaata aagaaagttc ctctaacacc
    11581 atgtcttttc aagatatcta gaacttgtgg agtattagta gtagatggtc catcatcaaa
    11641 tgtaagaaag actatctttt ctccattgtt tgaatagtcg tatttgttaa gtttgtccca
    11701 aactattttt gcgtcatatc catattcttt tacagcttct ttttttgcac caataatagg
    11761 ttcatttttt tctttttcaa ttctttcttt ttctaatctt tcagctttaa gtctttcttg
    11821 agtttctttc atttcttttt ttctagacat gtccgcccat gccatagaaa aaataccaat
    11881 aactattaca acaagtatag taagtgtaac agttttcttt tttctttttt ttaccataat
    11941 tacagcattc ccccttttgt cgaattgtat caaaaatata ttataattat atcgaagaaa
    12001 gtagaaaaag taaaccgaca aagttgtaac taagataact aaagtgtaac ttatatgaca
    12061 ttatttgcat aatattaaag tatcatatat attaaaaata tctataaaaa aatttagtat
    12121 aggtaaaaaa atataaaaaa tataaaaatt tattaaaaag gtgttt
//
LOCUS       DAMJYN010000100        11995 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.104, whole genome shotgun sequence.
ACCESSION   DAMJYN010000100 DAMJYN010000000
VERSION     DAMJYN010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11995)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11995)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11995
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.104"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            130..1329
                     /locus_tag="PC466_003141"
     CDS             130..1329
                     /locus_tag="PC466_003141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanyl-tRNA editing protein AlaX-L"
                     /protein_id="HDF2770501.1"
                     /translation="MEKLYYTNQYIRDFTAEIIEIKEVENKYHVLLDKTAFFPGGGGQ
                     FGDLGKIENDDVINVYEDGKNIYHVLDKKPIKIHKVKCSIDWDRREDGMHQHFGQHVL
                     SGCFFKTFNANTTGFHLGNEYSTVDIEGNLEENKIREIELFANEIIRQNIQVETLLPT
                     KKELKKIWLRRDLPNTDEEIRVIKIGDLDTNACCGVHPKSTGELRMIKIKKWEKHKSS
                     TRIEFLAGKRAVDEVLKRDIYLTKICRYLSCSEEDAINGIVNLNSKVEEALIKKRRLE
                     EVVSTYQVKEMIEKANKVGNISVIKKIYDDEDLKYVNKIANKIAEYENSIALLAVKFN
                     DKINLVFACSKNLKDINMGVLLKDAISLIDGKGGGSKVLAQGGGKNNGNLEATLDYAF
                     MKIEKTL"
     gene            1381..1884
                     /locus_tag="PC466_003142"
     CDS             1381..1884
                     /locus_tag="PC466_003142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2770502.1"
                     /translation="MEQQKDYIELYENEELIEIREARMDDLDTIAKFNYNLAKETEGK
                     ELDMDVLTKGVKALLLDERKGKYHVYTVFDKVVAQIMYTYEWSDWRNGNFLWIQSVYV
                     DKEYRRKGIFNYLFNYIKNICDKDENIVGMRLYVEKENINAKATYESLNMYECDYNMY
                     EYEVIHS"
     gene            1991..2308
                     /locus_tag="PC466_003143"
     CDS             1991..2308
                     /locus_tag="PC466_003143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770503.1"
                     /translation="MGVLKGMFYVFLFLDLVSIFCFFFNKGKIASNKIVFNAIGVLTF
                     VLCFMLFSYYPNNNLIGKFIASLFFIFGVAGVMLKEKNFLYARLLLTVVIVFSTLRLF
                     VIQ"
     gene            2466..3425
                     /locus_tag="PC466_003144"
     CDS             2466..3425
                     /locus_tag="PC466_003144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HDF2770504.1"
                     /translation="MIESKKSEKLLLSIIYIIFLVYILMIIRIILFRDVPIYAIFKGT
                     FRNVNLIPFYTIYQFIVDSNLDFMKATVNIIENIGIFIPMGIFLPIVCKNLNKKTIII
                     VIILVSLAFELTQYIFALGSSDIDDVILNSLGGIIGINIYINMNKLFPNDIKRFKAII
                     ATSLVLGVLGLGVISKNYHNLLTFKFRPDRKISKILIEENREIIKDINKDTVDIVGTF
                     ESFKKGIITIKAGSNNKVKRPENLIDSDGNIRIYLNENTKLVSYIITKESKMDIVKYE
                     EFDVKNLDLLRRYDTINVWIDKENQPKDKHGIMASKLLIGLYE"
     gene            3540..4325
                     /locus_tag="PC466_003145"
     CDS             3540..4325
                     /locus_tag="PC466_003145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative ABC transporter permease"
                     /protein_id="HDF2770505.1"
                     /translation="MEIIKYILYFFIYSFLGWTVESIGCSIASKRIINRGFLNGPICP
                     VYGFGAVIVISLLGRFNNVVIVFLLGMILTTILEYFTGFILETLFHAKWWDYSDRKFN
                     IKGRVCLKNAIYFGVMSVLIIRFIHPFIKYFVSIIPYRILISMAIITTLWTILDLIVT
                     IITLKKLDIKLNLLDDIITDLNDINVKLDKFDRGEIQALFKTINNDGLEVREKINKIN
                     SKLDRIESNIILQKRVIKAFPHIKHKKQQEQLEHFKKIINEKR"
     gene            4617..5936
                     /locus_tag="PC466_003146"
     CDS             4617..5936
                     /locus_tag="PC466_003146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class III-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HDF2770506.1"
                     /translation="MSEITSQMISTEEKKYVAKTQKIPYYPVAFKSGDGAMLYDYEGN
                     EYVDFLASAGSANVGHGNKEISQAVKEQMDDITQYTLAYFHSDPPVKLAEKLVEIAPG
                     DNDKKVLYSATGSACIDAAIKLARGYTGRTKIISMCESYHGSTYGAISISALSTNMRR
                     KMGPLLPEVYHFHYPDKNRTAKECLDEIEYAFAHYLPAEEVAAIFIEPIAGDAGIIVP
                     PVEWVQGLSKICKENGILLVSDEIQQGMGRTGKWFGIENFGVEADLIVLGKSVGGGLP
                     LGAVVGRTEIMQSLDAPAHLFTLAGNTTVCVAALKSIEIIEKENLLQKSIEMGDYIKA
                     GFEKLKEKYDIIGEIRGIGLSIGVDIVKGKGSNEKHPDATAKICYRCIQTGLIMIFLG
                     QSTLRVQPPLVITKEQVDKAMSIIDSAIDDYLNGRIGDEVYEVTQGW"
     gene            complement(6011..6439)
                     /locus_tag="PC466_003147"
     CDS             complement(6011..6439)
                     /locus_tag="PC466_003147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770507.1"
                     /translation="MKDNNNTNKTIQFGEKKASLENNIQKNKNIKLDNTHKVIPYPKN
                     RKKDDKKKGNKKKNTNTSKVNKNNYGHSFFNNKYKYKRKPYVIALYTVILILLAILII
                     TKLTDSTNKGNYSRNTVSDTHKNDIRNIVFNESNNFLICG"
     gene            complement(6530..7906)
                     /gene="hydG"
                     /locus_tag="PC466_003148"
     CDS             complement(6530..7906)
                     /gene="hydG"
                     /locus_tag="PC466_003148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[FeFe] hydrogenase H-cluster radical SAM
                     maturase HydG"
                     /protein_id="HDF2770508.1"
                     /translation="MFINHELINSLLEDAKNSTSDDIEKVLDKADRREKLSYKDIATL
                     LEVEDKKQLDRLFSIAGQIKNEIYGNRVVLFAPLYVSNYCVNECVYCGFSKCNKFKRK
                     KLTMEEIKEEVKILEKMGHKRLALEAGEDPKNCDINYILDCLDAIYSTYNENGNIRRV
                     NVNIAATSVDEYKLLKEKGIGTYILFQETYHKPTFIKMHGQSIKNDYYYHLTAFDRAM
                     EAGVDDVGAGVLFGLSDPKFEVLGLMMHNEHLEEKFGVGFHTISFPRLKKAEGMSLED
                     FPHLVSDDMFKKIVAITRLAVPFTGIIMSTRETAEMRNELLKYGVSQISAGSLTGVGG
                     YKAYEDGDNTEQFEVGDHRSPVEVLKELITDGYIPSYCTACYRKGRTGDRFMSLAKSR
                     QIHNVCTPNALTTLNEFLIDYGDEELKIMGKKLIAEEIGKIEREDIRNIVSNNMTALE
                     RGERDLYL"
     gene            complement(7907..8992)
                     /gene="hydE"
                     /locus_tag="PC466_003149"
     CDS             complement(7907..8992)
                     /gene="hydE"
                     /locus_tag="PC466_003149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[FeFe] hydrogenase H-cluster radical SAM
                     maturase HydE"
                     /protein_id="HDF2770509.1"
                     /translation="MTKNKIKYFIDKLYSINSLSFDELLYLIENIDNEEYNFEQNLRN
                     YLYKQASDMRNKHYGNRVYLRGLIELTNYCKNNCYYCGIQSSNKNIIRYRLSPDEILE
                     CCDIGYKIGYRTFVLQGGEDAYFTDDKICEIVSSIKNKYEDCAITLSLGEKSYDSYKK
                     YFLCGADRYLLRHETATDSHYKKLHPPNIELRTRKECLKNLKEIGYQVGAGFMVESPF
                     QNNKDLVRDLLYLKELNPHMVGIGPFIPHHDTIFKDYKHGDLEKTLLMLSITRLLLPK
                     VLLPATTALASINPSGRNAGLLAGCNVIMPNLSPQEFRKQYSLYDNKAFTGQEACEYH
                     QSLEENIKSLGLEVDYSRGDNIEWRRL"
     gene            complement(9028..10236)
                     /gene="hydF"
                     /locus_tag="PC466_003150"
     CDS             complement(9028..10236)
                     /gene="hydF"
                     /locus_tag="PC466_003150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[FeFe] hydrogenase H-cluster maturation GTPase
                     HydF"
                     /protein_id="HDF2770510.1"
                     /translation="MSLNSTPQSVRVHIGLFGKRNAGKSSIINAITNQSAAIVSDIAG
                     TTTDPVFRPMEILPIGPCVLIDTAGLDDVGELGELRIGKSLDVLEKTDIALLVVDCQI
                     GISQEDLSLIEKFNDKNIPHILILNKIDTIKNQSEILNLTKNKVKCPVVSVSSTDKIG
                     IENLKNEIIKVLPKDSTEFKLVSDLIEPNDLVVLVVPIDKAAPKGRLILPQQQVIRDI
                     LDNGAISIVTKEDSLKETLSNLGKKPKLVITDSQVFPQVNKDTPKDIPLTSFSILFAR
                     QKGDLKELINGAYALENLKDGDKILMAEGCTHHRQTDDIGTVKIPNMIRKKTGKNITF
                     EFSSGVSFTEDINKYALVVHCGACMMNRAGMLSRIEKAKSFNVPIVNYGILIAYVKGI
                     LERSLELFNY"
     gene            complement(10251..10502)
                     /locus_tag="PC466_003151"
     CDS             complement(10251..10502)
                     /locus_tag="PC466_003151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003361768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-only hydrogenase system regulator"
                     /protein_id="HDF2770511.1"
                     /translation="MKKVAVISAILEEPKECQFKFNEVVSGFKGIIKGRMGIPCEEEG
                     VSIVCIAVVGEMDTINSLTGKLGNIPHVSVKTSISKKEV"
     gene            complement(10883..11923)
                     /locus_tag="PC466_003152"
     CDS             complement(10883..11923)
                     /locus_tag="PC466_003152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HDF2770512.1"
                     /translation="MNLNLTNTINLMKKYLDIPSPAGYTENAVLEIKKDFENLGLDTI
                     LTKKGALIATLPGEDDSNQITISAHMDTLGAIVKEISSDGTLKYHKVGGGCWAAIEGE
                     NCTVITRKGKKIRGSVVFKYASTHIYGQTKAATERNEETMIIRLDEKVFTKQDVLDLG
                     ISVGDFVCLDHRFEATESGFIKSRYIDNKSAVAMVLEICRYFKENNLTPKHTTNFYIS
                     NYEEIGHGVSKCLPEKTKEFVAIDIAPTGPSQTSSEHGVTIVAKDNLSLYDFNLRNKL
                     VDVAEDNNLDYAVDVFTFYGSDASEAIRWGEDVQIACVGPGTNNSHHYERTHIEAIEN
                     TLKLLINYMLKE"
BASE COUNT         4395 a         1495 c         1818 g         4287 t
ORIGIN      
        1 aatatagtag aagatgttag taaataatag gatgagttct attttaatac aattaaatta
       61 agcttagctt gaaatttgta tttaaaaagt aaagtagtct ataattaaga aaatggagat
      121 agaattataa tggaaaagtt atattataca aatcagtata taagagattt tacagcagaa
      181 ataattgaaa taaaagaagt agaaaataag tatcatgttt tattagataa gacagctttt
      241 tttcctggtg gaggaggtca gtttggagac ctgggaaaaa tagagaatga tgatgtaata
      301 aatgtgtatg aagatggaaa aaatatatac catgtattag ataaaaaacc tataaagata
      361 cataaggtaa agtgtagtat tgattgggat agaagagaag atggaatgca tcaacatttt
      421 ggacaacatg tattatctgg atgttttttt aaaactttta atgcaaatac gacaggtttt
      481 catttaggaa atgagtatag tacagtagat atagaaggta atttagaaga gaacaaaatt
      541 agagagatag agttgtttgc caatgaaatt attcgccaaa atatacaagt agagacatta
      601 cttccaacga aaaaagaact aaaaaagatt tggttaagac gtgatttgcc aaatactgat
      661 gaagagataa gagtaataaa aataggtgat ttagatacga atgcatgttg tggagtgcat
      721 ccaaaatcaa ctggtgaatt gagaatgata aaaataaaga aatgggaaaa acataagtca
      781 agtacaagaa tagagtttct agcaggtaaa agggcagtgg atgaagtatt gaagagggat
      841 atatatttga ctaaaatatg tagatattta agctgtagtg aggaagatgc tataaatggt
      901 attgtaaatc taaatagtaa agtggaagag gctttaatta aaaaaagaag gcttgaagaa
      961 gtagtatcta catatcaggt caaagaaatg attgaaaaag caaataaggt tggcaatatt
     1021 tcggtcatta aaaaaattta tgatgatgaa gatttgaaat atgtaaataa gatagcaaat
     1081 aaaattgcag aatatgaaaa tagtattgca ttattagctg ttaaatttaa tgataaaata
     1141 aatttagttt ttgcatgttc taaaaattta aaagatatta atatgggagt tttattaaag
     1201 gatgcaataa gtcttataga tggcaagggt ggtggaagta aagtattagc tcaaggagga
     1261 ggtaagaata atggaaattt agaggctaca cttgattatg catttatgaa gatagaaaaa
     1321 actctataaa tatattatat aaaaaacctt agtagataaa atagatatgg aggaataagt
     1381 atggagcaac aaaaggacta catagagtta tatgaaaatg aagaactaat agagataaga
     1441 gaagcacgta tggatgattt ggatacaata gcaaaattta attataattt ggctaaagaa
     1501 actgaaggaa aagaacttga tatggatgtt ttaactaaag gtgtaaaagc attgttatta
     1561 gatgagagaa aaggaaaata tcatgtatat acagtatttg ataaagttgt tgcacagatt
     1621 atgtatacat atgagtggag tgattggaga aatggaaatt tcctttggat tcagagtgta
     1681 tatgtagata aggaatatag aagaaaaggt atctttaatt atttatttaa ttatataaaa
     1741 aatatatgtg ataaagatga aaatatagtt ggaatgagat tatatgtaga aaaagaaaac
     1801 ataaatgcaa aagcaacata tgagtcttta aatatgtatg agtgtgatta taatatgtat
     1861 gaatacgaag taatacattc gtaatataaa tttgtaatac tgttatactg atgttataaa
     1921 gtattgatta tattgacgat tatatgaaat aaactggata ttataattag aatttttagg
     1981 gggtataaaa atgggcgttt taaaaggaat gttttatgta tttttatttt tagatttagt
     2041 gtcaatattc tgtttctttt tcaataaagg aaaaatagca tctaataaaa ttgtgtttaa
     2101 tgcaatagga gtacttacat ttgtactttg ttttatgctt tttagttatt atcctaataa
     2161 taatcttatt ggaaaattta ttgcttctct attttttata tttggagttg caggagttat
     2221 gttgaaagaa aaaaattttt tatatgctag acttctttta actgtagtta tagttttttc
     2281 tacattaaga ttgttcgtta ttcaataaaa tgtatttgta tgaaaattta ttaaagtcta
     2341 cacatttaag tgtaggcttt tttgattttt tgtttgaaaa ttaaggaaat tttaaggaaa
     2401 ttttaaaatc gtcttaaata tttattgata tacttaaaat attaatagcg aaaggagact
     2461 tatcagtgat agaaagtaaa aagtcagaaa aattgttact gtcaattata tacataatat
     2521 ttttggtata tattttaatg attataagaa taattttatt tagagatgta ccaatttacg
     2581 ctattttcaa gggaacgttt aggaatgtaa atttaattcc attttataca atatatcaat
     2641 ttatagtaga tagtaatctt gactttatga aagctactgt aaatattata gaaaatatag
     2701 gtatatttat tcctatggga atttttttac ctatagtatg taaaaatcta aataaaaaaa
     2761 ctataattat agtaattata cttgttagcc tagcatttga attaacacaa tatatttttg
     2821 ctcttggaag tagtgatata gatgatgtta ttttaaattc attaggtgga ataattggaa
     2881 ttaatattta cataaacatg aataaattat ttcctaatga tattaaaaga tttaaggcta
     2941 taatagctac tagtttagtt ttaggagttt taggattagg agttatttct aaaaattatc
     3001 ataacttact aacttttaaa tttagacctg atagaaaaat atcaaaaata ttaattgaag
     3061 aaaataggga aataattaaa gatataaata aagatacagt agatatagtt gggacatttg
     3121 agagctttaa aaaaggaata ataactatta aagcaggttc taataacaaa gtaaagagac
     3181 cagagaattt aattgattct gatggaaata taagaattta tttaaatgaa aatacaaaat
     3241 tagtatctta tataattacc aaagaatcaa aaatggatat agttaaatat gaggaatttg
     3301 atgtgaagaa tttagattta ttaaggagat atgatactat taatgtttgg attgataaag
     3361 aaaatcagcc aaaggataaa catggtatta tggctagtaa attattaatt ggattgtatg
     3421 aataaaatat taaacaagaa taaaagaata acaaatataa aaaacgaaaa aactatttct
     3481 ataattattt ttacgttgtg cataaaataa gaacattagt gaaggagtag agataaatta
     3541 tggagataat aaaatatatc ttgtactttt ttatatattc atttttagga tggacagtag
     3601 aaagtatagg atgttctata gcaagcaaaa gaataatcaa cagaggtttt ttaaatggtc
     3661 caatatgccc tgtttatggt tttggagcag taattgtgat atcactatta ggaagattta
     3721 ataatgtagt aatagtattt ctattaggaa tgattttaac tacgatacta gaatatttta
     3781 caggatttat tttagaaacc ttatttcatg ctaaatggtg ggattattct gacagaaaat
     3841 tcaatataaa gggtagagta tgtttaaaaa atgcaatata ctttggtgta atgtctgttt
     3901 taataataag atttatacat ccatttataa aatattttgt aagtataatt ccatatagaa
     3961 tattaatttc aatggctata attacaacac tttggactat acttgatttg attgttacta
     4021 ttataacact taaaaaatta gatataaagt taaacttact agacgatata attacagacc
     4081 ttaatgatat aaatgtgaaa ttggataaat ttgatagagg agaaatacaa gctttattta
     4141 aaacaataaa taacgacgga ttagaagtta gagaaaaaat aaacaaaata aatagtaagt
     4201 tggaccgtat agagtctaat attattttac aaaaaagagt tataaaagca tttccacata
     4261 taaaacataa aaaacaacaa gagcaactag aacattttaa aaaaattatt aatgagaaaa
     4321 ggtaattata caatttaatg aagacgaata gaataatggt atttataaga ttattttcag
     4381 aggactctat aaaaatagaa tagagtcctt tattttttga aaaataatgt ttatttgata
     4441 aaaataaaat atattgtttc taaataacaa atattttgaa aattataaaa acatatattg
     4501 acaatttgtg tcaaaaatac taacattaag tatataaaga attttatatg agaatatctt
     4561 tataaatcgc aataatttta gaacataaat ttatttaaag aggggatgat ttgccaatga
     4621 gcgagataac tagtcaaatg ataagtacag aagaaaaaaa atatgttgct aaaactcaaa
     4681 agatacctta ttatccagta gcatttaaat caggtgatgg tgcaatgcta tatgattatg
     4741 aaggtaatga atatgtagat tttttagcaa gtgcaggctc tgcaaatgta ggtcatggta
     4801 ataaggaaat ctcacaagca gttaaagaac aaatggatga tataacacaa tatacacttg
     4861 catatttcca tagtgatcct cctgtaaaat tagctgagaa gcttgtggaa atagcccctg
     4921 gagataatga taaaaaagta ctatacagtg caactggttc tgcttgtata gatgctgcta
     4981 taaaattagc aagagggtat actggaagaa caaagataat atctatgtgt gaatcttatc
     5041 atggaagtac ttatggagct atatctatat ctgctttaag tacaaatatg agaagaaaaa
     5101 tgggtccatt gttaccagaa gtttatcact tccattatcc tgataaaaat agaacagcta
     5161 aagaatgttt agatgagata gaatatgctt ttgcacacta tctaccagca gaagaggtag
     5221 ctgcaatatt tatagagcca attgcaggag atgcaggaat aatagtgcct ccagtagagt
     5281 gggtacaagg tttaagtaaa atatgtaaag aaaatggaat attacttgta agtgatgaaa
     5341 tacaacaagg tatgggaaga acaggtaagt ggtttggtat agaaaatttt ggtgttgaag
     5401 cagaccttat agttcttgga aaatctgttg gaggtggatt acctttagga gcagttgttg
     5461 gaagaacaga aataatgcaa agtcttgatg caccagcaca tttatttact ttagctggaa
     5521 atacaacagt gtgtgtcgct gctttaaaat ctatagagat aattgaaaaa gaaaacttac
     5581 ttcaaaagag tatagaaatg ggagattata ttaaagcagg atttgaaaaa ctaaaagaaa
     5641 aatacgatat aattggagaa ataagaggaa tagggttatc tataggagtt gatatagtta
     5701 aaggaaaagg ttctaatgaa aaacatccag atgctacagc taagatatgt tatagatgta
     5761 tacaaactgg attaataatg atattcttag gacaatctac tttaagagta caaccacctc
     5821 tagtaataac taaggagcaa gtagataaag caatgagcat catagattct gcaatagatg
     5881 attatttaaa tggtagaatt ggtgatgaag tatatgaagt aactcaaggt tggtaaaata
     5941 aatattaaat gaaaaaaaga gttatctcaa ttttagaaag taatttctga aatgagataa
     6001 ctcttttaag ttacccacaa ataagaaaat tgtttgattc attaaagact atatttcgga
     6061 tgtcgttttt gtgagtatca gagacagtat tacgagaata attaccttta ttcgtactat
     6121 ctgttaattt agttataatt aagatagcta aaagaataag aattactgtg tataaagcaa
     6181 taacatatgg ttttctttta tatttgtatt tgttattgaa aaaagaatgg ccataattat
     6241 ttttatttac tttagatgta tttgtattct ttttcttgtt acctttcttt ttatcatcct
     6301 tttttctatt tttagggtaa ggaatgactt tgtgtgtatt atcaagtttg atatttttat
     6361 ttttttgaat attgttttcc aggctagcct ttttttctcc aaattgaata gttttattgg
     6421 tattgttgtt atctttcaat gttaatctcc ctcccttaaa ctttcccttt agataatatt
     6481 actactaacc tatggaatat acaataaata atatataagt aataaaattt tataggtata
     6541 aatctctttc tccacgctct aaggcagtca tattgttaga tactatgttt cttatatctt
     6601 ctctttctat cttacctatt tcttctgcga taagtttttt acccataatt ttaagttctt
     6661 catctccata atcgattaaa aattcattta atgtagtaag agcatttggc gtacatacat
     6721 tatggatttg tcgactttta gctaagctca tgaatctatc gccagttcta cctttacgat
     6781 aacaagctgt acaataacta ggtatatatc catcagtaat cagttcttta agcacctcaa
     6841 cagggcttct atggtctcca acttcgaatt gttctgtatt gtcaccatct tcatatgctt
     6901 tatatcctcc aacacctgtt agagaacctg cactaatttg tgatacacca tattttagta
     6961 actcatttct catttcagca gtttctctag tggacattat gattccagta aaaggaacag
     7021 ccaatctagt tatagctact atttttttga acatatcgtc agaaactaag tgaggaaaat
     7081 cttctaagct cataccttca gcttttttca atctagggaa agatatagta tggaaaccta
     7141 caccaaattt ttcctctaag tgttcgttgt gcatcataag tcctagaact tcaaatttag
     7201 ggtcagataa accaaataaa actcctgcac caacatcatc aacaccagct tccatagctc
     7261 tatcaaaagc tgttaaatgg taataatagt cattttttat agattgacca tgcattttta
     7321 taaatgttgg tttgtgataa gtttcttgga ataatatata agttcctatt cctttttctt
     7381 ttagtaattt atactcatct acacttgtag ctgctatgtt aacgtttacc cttcttatat
     7441 ttccgttttc attatatgtt gaataaattg catctaagca atctaagatg taatttatat
     7501 cacaattttt agggtcttca ccagcttcta gagcaagtct tttatgaccc attttttcta
     7561 atattttaac ctcttccttt atctcttcca tggtaagttt ttttctttta aatttgttgc
     7621 atttactaaa accgcaataa acacattcat ttacacagta gtttgataca taaagagggg
     7681 caaataaaac cactctatta ccatatattt cattttttat ttgcccagct atactaaata
     7741 atctatctag ttgtttttta tcttctactt caagaagtgt agctatatct ttataactaa
     7801 gtttttccct tctatcagcc ttatcaagta ccttttcaat atcatcagaa gttgaatttt
     7861 ttgcatcttc taataaagaa ttaataagtt catggtttat gaacatttac aaacgcctcc
     7921 attcaatatt atcaccgcga gaatagtcaa cttcaagtcc taatgacttg atgttttctt
     7981 ctaaactttg gtgatattca caagcttctt gaccagtaaa ggctttgtta tcgtaaagag
     8041 aatattgttt tctaaattct tgaggagaaa ggtttggcat aattacattg caaccagcta
     8101 aaagacctgc atttctacca ctagggttta tagatgccaa ggctgttgta gcgggtaata
     8161 aaacttttgg aagtagaagt cttgtaattg aaagcataag taatgtcttc tctaaatctc
     8221 catgtttata atccttaaaa attgtatcat ggtgtggaat aaaaggtcct attccaacca
     8281 tatgaggatt taactctttt aggtataata aatcacgaac aaggtctttg ttgttctgaa
     8341 atggtgattc aaccataaat ccagcaccta cctgataacc aatttcttta aggtttttta
     8401 ggcattcttt tctagttcta agctcaatgt ttggcggatg taatttttta taatgactgt
     8461 ctgtagcagt ttcatgtctt aaaagatatc tatctgcacc acataaaaag tattttttat
     8521 acgaatcata actcttttct cctagtgaca gagttatggc acaatcctca tatttatttt
     8581 ttatacttga aacaatttca catattttat catcagtaaa atatgcatct tcaccacctt
     8641 gcaaaacgaa tgttctgtat cctattttat aacctatatc acaacattca agtatttcat
     8701 caggtgaaag tctgtatctt atgatatttt tattagaaga ttgtattcca caatagtagc
     8761 aattattttt acaatagttt gtaagctcta taagtcctct caagtagact ctatttccat
     8821 aatgtttatt tctcatgtcg ctagcttgtt tataaagata gtttcttaaa ttttgttcga
     8881 agttatattc ctcattgtcg atattttcta ttaaatatag tagttcatca aaacttaatg
     8941 aattaatgct gtaaagttta tctataaagt atttaatctt atttttagtc atattcaaat
     9001 atgtaattat taagtatagt taaattttta ataattgaaa agttcaagtg atctttccaa
     9061 aatacctttt acatatgcta ttaagatacc atagtttaca ataggtacat tgaaagattt
     9121 tgccttttct attctagata acattccagc tctattcatc atacaagctc cacagtgaac
     9181 tacaagggca tatttattta tatcttcagt gaaggatact ccagaactaa attcaaaagt
     9241 aatatttttg ccagttttct ttctaatcat attaggaatt tttactgttc caatatcatc
     9301 agtttgtcta tgatgggtac atccttcagc catcaagatt ttatcaccat cttttaaatt
     9361 ttctaaagca taagctccat taatcaattc tttaaggtct cccttttgtc tagcaaacaa
     9421 tatagaaaaa gatgtaagag gaatatcttt tggtgtatct ttatttactt gtggaaatac
     9481 ttgagagtca gtaataacaa gttttggttt tttgcctaaa ttagatagag tttcttttaa
     9541 actatcttct tttgtaacta tagaaattgc accattatcc aaaatatctc ttataacttg
     9601 ctgttgagga agtataagtc taccttttgg agctgcttta tctattggaa caactaaaac
     9661 aactaaatca tttggttcaa ttaaatctga taccaatttg aactcagtgc tatccttagg
     9721 caaaactttt attatttcat tttttaaatt ttcaattcca attttatctg ttgatgagac
     9781 agaaacaact ggacatttaa ctttattttt agttaagttt aaaatttctg attgattctt
     9841 aatagtatca attttgttga gaattagaat atgagggata ttcttatcat taaacttttc
     9901 aattagtgac aaatcttctt gtgatatacc aatttggcaa tccactacta gtaaagctat
     9961 atctgtcttt tctaaaacat ctagtgattt acctattcta agttcaccaa gttcaccaac
    10021 atcatcaaga ccagcagtat ctataagaac acaaggtcct ataggaagga tttccattgg
    10081 tctaaatact gggtctgtag tagttccagc aatatctgag actattgcag cactttgatt
    10141 tgttatagca tttattatgc tagatttacc tgcatttctt ttaccaaaga gacctatatg
    10201 tactcttacc gattgtggag tagaatttag actcatttgt actcaccacc ttaaacttct
    10261 ttttttgata tactagtttt tacagataca tgaggtatgt tgcccaattt accagtcaaa
    10321 ctattaatag tatccatttc gccaacaact gctatacata cgattgagac accttcttct
    10381 tcgcaaggaa tgcccattct tcctttaata atacctttaa aacctgatac aacctcattg
    10441 aatttaaatt gacattcttt tggctcttcc aaaatagcac ttataactgc aacctttttc
    10501 ataaatatcc tcctaactca gaaaatatgt cttaaacaaa tccaaaatca aaaaactttt
    10561 ctttgtaaag aaaagtttct acaaaagaaa agttattaat tacacaagta taatgtgcta
    10621 tattaaacta tttccttaca gattagataa ctcttttctg gtagggttag cttgtaaaaa
    10681 tttaatttaa caacaagtaa ctgaagaaaa tttttataca atttatataa attataataa
    10741 aaattaacta aagaaaattg aagttactta tataatagta gtaaattgaa attaagtcta
    10801 tagaaaaacc aatttttgta taaaaataaa aattaaagtt aattatttgt taagaattga
    10861 ctttggtaaa atatataatt aattattctt taagcatata atttataagt aattttagtg
    10921 tattttcaat agcttctata tgtgttcttt cataatggtg actattgttt gttccaggac
    10981 caacacatgc tatttgaaca tcttctcccc aacgaatagc ttctgaagca tctgaaccat
    11041 agaaagtaaa tacatcgaca gcgtagtcta aattattgtc ttctgcaaca tcgacaagct
    11101 tgtttcttaa attaaaatca tataatgata aattatcttt tgcaactata gttacaccat
    11161 gttcactaga tgtttgactt ggtccagtag gtgctatatc tattgctaca aattcttttg
    11221 ttttttcagg taaacattta gaaacaccat gtccaatttc ttcataatta cttatataaa
    11281 agttagtagt atgcttaggc gttaaattgt tttctttaaa atatctacat atttcaagaa
    11341 ccattgctac agctgattta ttatctatat atctagattt tataaaacca gattctgtag
    11401 cctcaaatct atggtctagg catacaaaat ccccaacact tattcctaaa tctaatacat
    11461 cttgctttgt aaatactttt tcatcaagtc taataatcat tgtttcttca tttctttcag
    11521 tggcagcttt tgtttgacca tatatatgag tagaagcata cttaaataca acacttcctc
    11581 tgattttttt accttttcta gttataacag tgcagttttc tccctctata gctgcccaac
    11641 atccaccacc aactttatgg tatttaagag taccatcaga tgatatttct tttactatag
    11701 ctccaagtgt atccatatgt gcagatattg ttatttgatt tgaatcatct tcaccaggaa
    11761 gagtagctat aagtgcacct ttttttgtaa gaatagtgtc aagacctaaa ttttcaaaat
    11821 cttttttgat ttctaaaact gcattttcag tatatccagc tgggcttgga atgtccaaat
    11881 attttttcat taaatttata gtattagtta aatttaaatt catattgttt cctcctaaat
    11941 aaatatattt atacaaatta taacataaat acaaatgttc tgaaaactaa aatta
//
LOCUS       DAMJYN010000101        11498 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.105, whole genome shotgun sequence.
ACCESSION   DAMJYN010000101 DAMJYN010000000
VERSION     DAMJYN010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11498)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11498)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11498
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.105"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(72..497)
                     /locus_tag="PC466_003153"
                     /pseudo
     CDS             complement(72..497)
                     /locus_tag="PC466_003153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902013.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosome-binding GTPase"
     gene            complement(970..1257)
                     /locus_tag="PC466_003154"
     CDS             complement(970..1257)
                     /locus_tag="PC466_003154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770513.1"
                     /translation="MRLNVTKQNTIEVENSRKEDVYFVIVDNVFFERQGDVFNSITNN
                     NLNNYDVKILPTDNVFLELKITSTKDLEPVFIVVEDRQYNHGSIMFKPVLV"
     gene            complement(1277..1552)
                     /locus_tag="PC466_003155"
     CDS             complement(1277..1552)
                     /locus_tag="PC466_003155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770514.1"
                     /translation="MSLFVGGWSKFRAVEEEDLKVFNEAIGMLKGVDYEPLIVATQVV
                     AGTNFKFICNATSVTNPPHDYLAEIIVFKPLPCDEHNATITSINIIK"
     gene            1740..2559
                     /locus_tag="PC466_003156"
                     /pseudo
     CDS             1740..2559
                     /locus_tag="PC466_003156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418025.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
     gene            complement(2818..5385)
                     /locus_tag="PC466_003157"
     CDS             complement(2818..5385)
                     /locus_tag="PC466_003157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002602373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate, phosphate dikinase"
                     /protein_id="HDF2770515.1"
                     /translation="MIYYVLPLEHKQATIEIVGGKGMSLSKLLTAGIPVPDGFHVTTA
                     SYQIFVETNHIQSRINKLLDGIDSNNTNQLEDVSKKIGELFHNGEMPQEVSDAIKTAY
                     AGLGNISVAVRSSATAEDLPDASFAGQQETYLNIQGEDKVIDAVKRCWASLWTARAIA
                     YRVKNNIKHEIVALAVVVQKLAFSDSSGIMFTLNPINGRRSEMIINAAWGLGEAVVSS
                     LVTPDTIVVDKDSERIISYEVANKEIMTVRTSEGTEETMVPERLRKKYALTRNQVMQL
                     IQLGKKIEKYYQMPMDVEWALEKDKLYIVQARPITVLPPEWVLPEQDVVYTKGSLAEH
                     LPNPVTPLFATLGLEIVNRASELLWIDMFGKSAKKLLPKNGAYTVINGYVYLSAKSKP
                     LLIAIKSLSPRSLRRTLMNSVARWETARKGYEDAIKQWEEKPLHTMNAHQIMDGIQTI
                     FYAACIYFTRIQLTLPAASISETLFTKLFQGAVRRAGITDTSVFLLGFDTIALQSEKE
                     LWGLSEWVKQNNSINLYLQNSPAIKIAEDFMSSVMPVGVSQEVWIEWKNRINKYFKEF
                     GRTAYEFDFAYSTPQETLTPTFESVKTFVEGKGESPFLRQTTFEKRRKHAEEEILQHI
                     GGLRKKLFFKLLHWAQETSPMRENAIYLMGMGHPLIRCMFQEISERFIRGGAISHLDD
                     IYWLTKSELEVLIEQLDKNKSLSDMNGIIPVRKAELKKYMGYVSPSKLPEKNKKTISQ
                     APQKQKDGKIVLTGIGTSTGVVTAPACVLNSPADFESFQPGSVLVAVTTTPAWTPLFS
                     SASAIVTDIGGPLSHSSIVAREYGIPAVMATHIATRTIKSGQMITVDGLAGTVTFDE"
     gene            complement(5388..5993)
                     /locus_tag="PC466_003158"
     CDS             complement(5388..5993)
                     /locus_tag="PC466_003158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002591427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2770516.1"
                     /translation="MPKGIVLTPEQQAERREKIVAVALSLMAENGFQKTSMREIAVLA
                     NMGKSSLYDFFKTKDEIVVYAVEKEIEKTIQQVHRIIDGEPSPQQCLRKIMLNHLRFP
                     EQYRTVLMWLNTESDYLEEEYRKRLKDARYAYQDIIKSVIDNGVTTGIFRKTDTALVT
                     RLLINSMLSISYTSRPSDSSEKMLDETMNIFLHGIMNDGGE"
     gene            complement(6367..7827)
                     /locus_tag="PC466_003159"
     CDS             complement(6367..7827)
                     /locus_tag="PC466_003159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HDF2770517.1"
                     /translation="MFNELKTKENVYKNLINGKWVESNSRKPIEIYSPIDNSLVGKVQ
                     SMTKHEVDEVIKNTKESIKVWAEMPVYKRANIFHKAADLLLENIDEIANILVLEIAKD
                     IKSARAEVERTADFLRYTADVGKNMEGEAISGDNFPGGTRNKMSYVSRVPLGTVLAIS
                     PFNYPVNLSMSKIAPALIGGNAVVLKPATQGAISALHVVEIMRKAGIPDGVLNTITGR
                     GSEIGDYVVTHKGINFINFTGSTEVGQHISKISGMVPLLLELGGKDAAIVLEDADLDF
                     AAKNIVSGAYSYSGQRCTAVKRILVQESVADKLVGKIKPLVEKLTIGNPMDEVVITPL
                     IDNKATDFVQGLVDDALHKGAKLITGNVRKNNLFYPTLLDNVNVDMKIAWEEPFGPVL
                     PIIRVKDINQAIEIANQSEYGLQSSVFTSDIDRAFYIADKLEVGTVQINNKTERGPDH
                     FPFLGVKASGMGTQGVKYSIEAMTRPKAVVVNVREL"
     gene            8158..8736
                     /locus_tag="PC466_003160"
     CDS             8158..8736
                     /locus_tag="PC466_003160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2770518.1"
                     /translation="MAKSFTEIEKDNIRKRLISECEINWSKYGYKKTNIDELCSKSGI
                     AKGSFYTFFDSKEKLFFEVLNGIQNRLISSVDEILSNMPPKEGFAKSLKMLYRLYDKN
                     PFLYSPNNPDFISLINKLPQDMFLQLESNNIQSFYDLIKRHNLKLKIEKEKAFGVCNS
                     LLSSLLVKENIEYNYIEVFDFMVDNLVEHILE"
     gene            9028..10278
                     /locus_tag="PC466_003161"
     CDS             9028..10278
                     /locus_tag="PC466_003161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2770519.1"
                     /translation="MVKSSNTFNKNFNLMILGQIISLFGASILKFALSLYILDITGKA
                     EIFATILAVSSIPIIVFSPIGGAIADIFNRRNLMVIFDFSSSLTVLILAVFLFNNNGS
                     ILLVGIIMTILSVISTMYQPTVQSSTPLLVDNEHLMNANGIVAGVASLTNIAGPVLGG
                     VLYGVIGINAIIVISCVSFFLSAIMEIFIQIPFIKQEQNSNIIKTIFTDIKDGIVHIC
                     KENRFILKILFLAIAINLFLSSMLIVGIPYIVKITMGASNFLYGLAEGAISFSSLVAA
                     VSIGIFSKHLKITNLHISFIICAVMFIPMAVSVYPFILNTGFPVPFLIFIVSSMLIFF
                     TTTLISIYVITVTQLKTPNELLGKVMSILFAGTAIAMPLGQVMYGKLFDLLSDRVYII
                     ILGVGFITLLIAFVSKITLRNENL"
     gene            10439..11008
                     /locus_tag="PC466_003162"
     CDS             10439..11008
                     /locus_tag="PC466_003162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HDF2770520.1"
                     /translation="MSYMPTLEQAWEILRKYNKEEFHIRHAQIVSGVMRYYAKEYDPE
                     RVDFWEIVGLLHDLDFEMYPDEHCVKQRELMTELDLDKSIIDSTISHGYGLTGSDVKP
                     EQFMEKVLFAVDELTGLIGAVAIMRPSKSVSDLELKSVKKKFKDKSFAAGCSRDVIRS
                     GAEMLGWELDKLIQTTIEAMRSLIPEMAI"
BASE COUNT         3802 a         1994 c         1588 g         4114 t
ORIGIN      
        1 gtttccctat atgctgacta ttttagctac taactcatga ctaaattcac gagtgtgcgt
       61 agctattttt taatcaatac aattactgca catatagatg cagaattttt aaatacttca
      121 cctaatgaaa ctgctgcact aatatcatgg gctactcccc tattgtcgct aaaacctgca
      181 gtatcacata attttgcatc cattccttct attggttttc tcatatttac aatgtttggg
      241 tataaagttt gagaaacagc tcctgaacca atctctgcca cagggtctaa gcaatcaata
      301 tatgatatac cagtatcttc atcttctact tccatcatta cacatcctgc aagatagtta
      361 attgcagtac ttttgccaca tcctgtccca ccaagaatta gaattaaatt ttgattttca
      421 gccttattta ttgctacttt tccttcattt aataagagtg ttatttcttc taaaagttga
      481 ttgttatttt ctggcattta ttttccccct tggttatata ttttatttaa ataaagttta
      541 atcccttaag tagattacaa agtttttaga ctatatttaa atttgttttt tatttttaat
      601 aaatttgcat tttcactcaa taattattct tctttgttta ttaaaataac tgtgttgtat
      661 aatataattt ttaccaacac agttatttta tttaatgcgc ttattttatt gtattttatg
      721 taatacagtt gtttttttat attatatgtc cactattttc ctatggttat tacatataga
      781 tttttaatta tatttgtacc attaatttaa acattcctat actactgctt aagttttaca
      841 cctataccag cttgaatatt ttatttttat ttgcttaaat agttcaacta tactggttta
      901 ataggtttcc tttagtttaa atagttcacc tatacctact tgaatagttc acttttattt
      961 gcttaaattc tataccaata ctggcttaaa cattatacta ccatgattgt attgtctatc
     1021 ttcaactaca ataaaaacag gttctaaatc tttagtagat gttattttta attctaaaaa
     1081 aacattatca gttggtaata tttttacatc ataattattt aaattattat tcgtgatact
     1141 attaaataca tcaccttgac gttcaaaaaa aacattatca actattacaa aataaacatc
     1201 ttcttttcta ctattttcaa cctctatagt attttgttta gttacattta gtctcatctt
     1261 ccacctccta ttaatattac ttaattatat taatacttgt aattgttgca ttatgttcat
     1321 cacaaggaag aggtttaaaa acaattatct ctgctaaata atcatgtgga ggatttgtaa
     1381 ctgaagtagc attgcaaata aatttaaaat ttgttcctgc tacaacttga gtagcaacaa
     1441 taagtggttc ataatcaacc ccttttagca ttcctatagc ttcattaaat acttttaaat
     1501 cttcttcttc gacagcccta aattttgacc atccaccaac aaaaagactc atataaaaac
     1561 ctcctttata tatatattta tttatatgat agtaccaatt ttcttaatat tcaatatatt
     1621 acgtctaact ggtcaataaa aatgcataac tggataaaaa gacttataaa atagcttaac
     1681 tttacatata ataagattat tctaaaatat gagacatatc ttgctttgaa tatattctat
     1741 acaacaattt tccaggcctc attgccaagt ttaaggtaac tgactttgga ttccaacttc
     1801 ttgatgctaa taaaaaatat tttgatatgt tcaaagataa tgtaaatttt ctattagatg
     1861 atataaattt agaaggttat cttaacaatg tgtataaata tcataatgat tttaaatctg
     1921 ggagatgcgt ttgtttttct atttctccac aaactattaa tggagatatt tttcacatgc
     1981 aagttgtagc tgaatgtata gattgggaag atgataagcc tatatatctt ttaatatatt
     2041 cagatgtaac gacattggta aaacaatatg tctcattatc atttttcatc caagaatttt
     2101 atcaagaaat atgataaaat agctaaaaaa tatgatattc cttctcacct tatagaaatt
     2161 gagattacag aaacaattgt atttgaagat gtcaaagtat ttagtgaaat aataaatgaa
     2221 attcataaaa atgactttaa atgctctatt gatgattttg gaagtggcta ttcttcaatc
     2281 aatatgctta agggtattta tgttgataca ttaaaattag atagagcatt ttttcaatca
     2341 gaagatttag attctcaacg tgaaagaaat ataattgtat ctataatcga actagctaaa
     2401 aagttaaaaa tgaccactgt agctgagaga atagagacca gttttcaaaa agatttcttg
     2461 caagaaataa actgtgatat gttacaagga tacgtgttct ctagaccttt gcaaataaaa
     2521 gactttgaaa aacttatgtt tcaaaactcc tccaattaac aatataaaat tgcttattat
     2581 aagtgtatta ttgtatcaac aaataaagga attgtctcaa aattgatttt ttctaatcaa
     2641 atttttattt tgagacattc tcattttttt gcataagaaa atacccacca agctacggtt
     2701 tttcttaccg ctgttcggtg ggtattagta gtattatgaa atctgaaaac tttaagtatt
     2761 actacttccg ctaacgcaat cacaaaggtc gaaagcttca aagcgaaaat aggcttttta
     2821 ctcatcaaac gtcaccgtac ctgccaaccc gtccaccgtt atcatttgtc cgctcttaat
     2881 agttcgtgtg gcaatgtgtg tagccataac ggctgggatg ccatattcac gtgcgacaat
     2941 gcttgaatgg ctaagaggac caccaatgtc cgttacaatc gcacttgcag atgaaaataa
     3001 tggtgtccat gctggagttg tggtaactgc aaccaaaaca cttccaggtt gaaagctttc
     3061 aaaatctgct ggactattca gtacacaagc tggagccgtc acaacaccag tactggtacc
     3121 aatgcccgtc aacacaattt tcccatcttt ctgcttctgt ggtgcttgtg atatagtttt
     3181 tttgtttttc tctggcaact tggacggtga cacataaccc atgtattttt taagttcagc
     3241 ttttcgaaca ggtattatcc cgttcatatc agatagagac ttgtttttat ccaactgctc
     3301 tataagtacc tccaattccg attttgtgag ccaataaata tcatctaaat gtgaaatagc
     3361 tcctcctcgt atgaatcgtt ctgagatttc ctgaaacata caacgaatca gaggatgtcc
     3421 cattcccatc aaataaatag cattttcacg cataggagag gtttcctgtg cccaatggag
     3481 caacttaaaa aatagttttt tacgcaatcc acctatgtgt tgtaaaatct cttcttctgc
     3541 atgttttcta cgcttttcaa acgtggtctg gcgtaaaaaa ggactttccc cttttccttc
     3601 cacaaatgtt tttacggatt caaaagttgg tgtaagtgtt tcctgcggtg tggaatacgc
     3661 aaaatcaaac tcataagcgg tacgaccaaa ctctttaaag tacttattga ttcgattttt
     3721 ccattctatc catacttcct gtgaaactcc aacaggcata actgaagaca tgaaatcttc
     3781 tgctatcttt attgcaggac tgttttgcag ataaaggttg atgctgttat tttgctttac
     3841 ccattctgaa agaccccaca actccttttc cgattgcaga gcaatcgtat caaacccaag
     3901 caggaaaacg gaagtatccg ttataccagc acgtcgaact gctccttgaa ataattttgt
     3961 aaataatgtt tcactgatag aagcagcagg caatgtaagc tgaatccttg tgaaataaat
     4021 acatgcggca taaaatattg tctgaatacc atccataatt tgatgggcgt tcatcgtatg
     4081 caggggcttt tcttcccatt gtttaatagc atcctcatat ccttttcgtg ccgtttccca
     4141 gcgtgcaacg ctgttcataa gtgtcctacg taaagagcgt ggggaaaggg atttgatagc
     4201 aatcaaaagt ggctttgatt tagcagaaag ataaacatat ccattaataa ccgtatatgc
     4261 gccgtttttt ggtaataatt ttttcgcact tttaccaaac atatctatcc ataaaagctc
     4321 cgatgcacgg tttacgattt caagaccaag cgtggcgaac aaaggtgtaa caggatttgg
     4381 caagtgttct gccaaacttc cctttgtgta tacaacatcc tgttctggca atacccattc
     4441 cggtggcaga acagtaattg gacgagcttg aacaatgtac aatttatctt tttccagtgc
     4501 ccactctaca tccataggca tttgataata cttctcaatt ttctttccaa gctgtatcag
     4561 ttgcattacc tgattacgag taagagcata tttttttctc aacctttcag gaaccatggt
     4621 ttcttctgtt ccttctgaag tacgaaccgt cataatctct ttatttgcca cttcatacga
     4681 tataattcgt tcggagtcct tatccactac gattgtatcg ggtgtaacta agctagaaac
     4741 caccgcttca ccaagccccc atgcagcgtt aataatcatt tcgctacgtc taccattgat
     4801 tgggtttaac gtaaacataa taccagatga atcggaaaat gcaagctttt gtactacaac
     4861 agcaagtgcg acaatctcgt gctttatatt attcttcaca cgataagcaa tagcacgagc
     4921 tgtccataag gaagcccagc atctctttac agcgtcaata actttatctt caccttgtat
     4981 gttaagataa gtttcctgct gacctgcaaa agaagcgtca ggtaaatctt cagcagtcgc
     5041 agacgaacga acagccaccg atatgttccc taatccggca taagctgttt taattgcgtc
     5101 cgacacttcc tgtggcattt ctccattatg gaaaagctcc cctattttct tagatacatc
     5161 ttcaagttgg ttggtattat tggaatcaat accatctagc agtttattaa ttcgagactg
     5221 aatatggttc gtctcaacaa aaatctggta tgaagcagtc gtaacatgaa aaccgtctgg
     5281 cacagggatg cctgctgtca atagttttga taaagacatc ccttttccac caacaatttc
     5341 aatggttgct tgtttatgtt ccagtggcaa gacataataa atcataatca ttcacctcca
     5401 tcattcataa ttccgtgcag aaatatattc attgtttcat ccaacatttt ttccgaacta
     5461 tccgatggtc gtgacgtgta gctgattgat aacatggagt taattaacaa acgtgtcaca
     5521 agagcggtat ccgttttgcg aaagatgcct gtggtcacac cattatcaat taccgatttt
     5581 ataatatctt gatatgcata acgagcatct ttaagtctct ttcgatactc ttcttctaaa
     5641 taatcagatt ctgtatttaa ccacatcagt acagttctat actgctctgg aaatctaaga
     5701 tgattaagca tgatttttct aaggcactgt tgtggtgaag gttcaccatc aataatccta
     5761 tgaacttgtt ggatagtttt ttctatttct ttctcaactg catatacaac aatctcgtct
     5821 ttcgttttga aaaaatcgta tagacttgac tttcccatgt tggctaaaac tgcaatttct
     5881 ctcattgatg ttttttggaa tccattttca gccatgagac tcaaagcaac agcaactatt
     5941 ttttctcggc gttctgcttg ttgttcaggt gtaagcacaa ttccttttgg catagggcga
     6001 tacctccttt tagcgaccaa tggtcgtttc ttttttattt atcatacagc gaccatcggt
     6061 cacttgtcaa ggttaatttt tttcattgta tatggtactc gagataaaaa tgttcatttt
     6121 agaaattgct ctatttaagt agaaataggc ttcatcatta gaaaacaaga ctataaattt
     6181 gagatattta tcatgttcaa atttcatcaa tatcaaagtt taagatatta ataaaaaaag
     6241 aattactaag aaataacata taaagattca aaaaaggagt tgaacttaaa attcaattac
     6301 aaaaaatcaa atttaagaca actcctttat tctttatctc tactattctt tatctctatt
     6361 tatttattac aactccctaa catttaccac tactgcctta ggtctagtca tagcctcgat
     6421 tgaatactta acaccttgag ttcccatacc agatgccttt acacctaaaa atgggaagtg
     6481 gtctggacct ctttcagtct tattatttat ttgaacagta ccaacttcaa gtttatcagc
     6541 tatataaaat gccctatcaa tatcacttgt aaatactgat gattgaagcc catactctga
     6601 ttgattagca atttcaattg cttgatttat atctttaact cttataattg gaagtactgg
     6661 accaaatggt tcttcccaag caattttcat atcaacattt acattatcta acaatgttgg
     6721 atagaataaa ttattttttc taacattacc tgttattaac tttgctcctt tatgtaatgc
     6781 atcatcaacc aacccttgaa caaaatcagt tgctttatta tctataagag gagtgataac
     6841 tacttcatcc attggatttc caattgtcaa cttctctacc aatggcttta tttttccgac
     6901 taatttatcc gccacactct cttgtactaa aattctcttt actgccgtac atctttgtcc
     6961 tgaatatgaa tacgctccag atactatatt cttagctgca aaatctaagt ctgcatcttc
     7021 taatactata gccgcatctt ttccaccaag ctccaataat agtggtacca ttccagatat
     7081 tttagatata tgctgaccaa cttcagtact accagtaaag ttaataaaat taattccttt
     7141 atgcgttaca acataatccc ctatctcact acccctacct gtaatagtat taagtactcc
     7201 atctggtatc ccagcttttc tcatgatttc taccacatga agtgcgctaa tagccccttg
     7261 tgtagcaggt tttaatacaa ctgcatttcc accaataagc gctggagcaa tctttgacat
     7321 tgataaattt acaggataat taaaaggaga tatagctaaa acagtaccta atggaaccct
     7381 tgaaacataa gacatcttat ttcttgttcc accagggaaa ttatctccac taatggcttc
     7441 accctccata ttttttccca catcagctgt gtatcttaaa aaatctgctg ttctctcaac
     7501 ttctgccctt gcagatttta tgtctttggc tatttcaagt accagtatat tagctatctc
     7561 atctatattt tctaacaata aatcagcagc cttatgaaat atattggctc tcttgtatac
     7621 aggcatttca gcccatactt ttatactctc ttttgtgttt tttataacct catctacctc
     7681 atgttttgtc atagattgta ctttcccaac aagagaatta tctattggtg agtaaatttc
     7741 tattggcttt ctcgaattag attctaccca ttttccattt attaaatttt tatatacatt
     7801 ttcttttgtt ttaagttcat taaacatatt tttattcctc tctctgatat aactttgtgt
     7861 atttaaatta tagccattta ttcgttatgt aaacatttct ttttttcata aacgtttacc
     7921 tataaaaaaa attttaagtt aacgtttttc tagattcttc tattttaata acatactcgc
     7981 tccaaatcta tataggtcac actttaatat caatatacca atataccaat ataccaatat
     8041 aaatattata aacataaatc acttgacaaa tttataagta gacaatatta tatatctatg
     8101 acttaaaata tttttaaagt catagatagc atatgcagat agaaaggatt gataaaaatg
     8161 gctaaaagtt ttacagaaat agaaaaagac aatataagaa aaagactaat ttcagaatgt
     8221 gaaatcaact ggtctaaata tggatacaaa aaaactaaca ttgatgaact ttgttcaaaa
     8281 tcaggaatcg caaagggttc tttctataca ttttttgatt caaaagaaaa gttatttttt
     8341 gaagtactaa atggaatcca aaacagactt atatcatcag tagatgaaat tttaagtaac
     8401 atgcctccaa aagaaggctt tgcaaaatcc ttaaaaatgt tatatcgatt atatgataaa
     8461 aatccatttt tatattcacc aaataatcct gatttcatca gcctaataaa taaactacct
     8521 caagatatgt ttttacaact tgagtccaat aacatacaaa gtttttacga cttaattaag
     8581 agacacaatc tcaagttgaa gatagaaaaa gaaaaagcct ttggtgtttg taattctcta
     8641 ctatcaagtc tattggtaaa agaaaatatt gaatataact atattgaagt atttgatttt
     8701 atggtagata atcttgtaga acacatactt gaataacaat ttaaaataat ttttctaaat
     8761 atttctttat actaaagagg attaatatga ttgaattaat gaaaaaaata aacaatatca
     8821 tttacaaaat aaatgataaa ctaaatatac acacaaaact tatagacccc agagttaact
     8881 cattccactc tactctaagc catctataat agttcgtata tttctaataa tattagatat
     8941 taaagtaaga aaaaaattcc ttataataat tgctattata tcaattatta taaatatttt
     9001 aataatctta gataggtagg tatatatatg gtaaaatcct caaacacttt taataaaaac
     9061 ttcaacttga tgatattagg tcaaataatc tcattgtttg gtgcatcaat acttaaattt
     9121 gctttatctt tatacatact tgatataact ggtaaagcag aaatatttgc tactatacta
     9181 gcagtatctt caatcccaat tatagtattc tcccctattg gtggagctat tgcggatata
     9241 ttcaacagaa gaaacttaat ggttattttt gatttttcaa gcagtcttac agtactaatc
     9301 ttagcagtat tcttattcaa caataatggt tcaatattac ttgtaggaat tattatgacc
     9361 atattatcag ttataagcac aatgtatcaa ccaactgttc agtcaagtac acccctttta
     9421 gttgataatg agcatttaat gaatgcaaat ggtattgtag ctggagttgc atctcttaca
     9481 aatattgcag gacctgtatt aggaggtgtc ttgtatggtg tgattggaat taatgcaatt
     9541 atagttataa gttgtgtaag tttctttcta tctgcaatta tggagatatt tatacagatt
     9601 ccttttatca aacaagagca aaacagcaac attataaaaa ctatatttac tgatataaag
     9661 gatggtattg ttcatatatg taaagaaaat agatttatac taaaaatact ttttttagct
     9721 atagcaataa acttattttt aagctctatg ttaatagttg gtatccccta tatagtaaaa
     9781 atcactatgg gagctagtaa cttcttatat ggtctagcag aaggagcaat ttcttttagt
     9841 tcactggtag ctgctgttag tattggtatt ttctcaaaac atctaaaaat cactaatttg
     9901 cacatttcct ttattatatg tgcagttatg ttcataccaa tggcggtttc agtatatcca
     9961 tttatattaa acacaggatt tccagttcca tttttaatct ttatagtatc atctatgcta
    10021 atatttttta caacgactct tatctcaata tatgttataa cagtcacaca attaaaaact
    10081 ccaaatgaac tcttaggaaa agtaatgtca attctttttg caggaacagc aattgcaatg
    10141 cctcttggtc aggttatgta tggtaaactt tttgatttat tatcagatag agtgtacatc
    10201 attatactag gagttggatt tattacacta cttatagcat ttgtatcaaa gataacattg
    10261 aggaacgaaa atctttagat acaaagaatt tagatataaa gatttaattt tcactaattt
    10321 ctgaatttaa atgcaaaatt gcgtatcagt atgttgacgt tttagaaatt gattgatata
    10381 atcaatggaa aataaacttt ataaaaattc aaaatattca gctagaggag tgataaaaat
    10441 gagttacatg ccaactttag aacaagcatg ggaaatatta agaaaataca ataaggaaga
    10501 atttcatata agacatgctc aaattgtatc tggagttatg agatactatg caaaggagta
    10561 cgaccctgag agagtagact tttgggaaat agttggactt ttacatgatt tagattttga
    10621 aatgtatcct gatgaacatt gtgttaaaca aagagaatta atgacagagc ttgatttaga
    10681 taaatcaata atcgattcta caataagtca tggatatgga ttaactggtt cagatgttaa
    10741 accagagcaa tttatggaga aagtattatt tgctgtggat gaacttactg gtttaattgg
    10801 tgctgttgca ataatgcgtc cttcaaagag cgtttctgat ttagaattaa aatctgttaa
    10861 gaagaaattt aaagataaat catttgctgc tggctgttct cgagacgtta taagaagtgg
    10921 tgcagaaatg cttggatggg aacttgataa gcttatccaa acaactatag aagctatgag
    10981 aagcttgatt ccagagatgg caatatagct cctcatacat ataccataga agttacatct
    11041 ttaaagagca tttctctttt tgatgcaact tctttttata ttttgtagaa taaaaagttt
    11101 aatattttaa actcactata taatctataa taaatactat aaataatata atgtataata
    11161 gtcataaact ttctaacctt aaaagtttct aatactcaat aaacaattct aatatacaag
    11221 tggcattata tgatttaatt atatatcttc aatttatata ttaaaataaa tatatatatt
    11281 aaattcttat acaccaaatt tttacattaa acttctatgc accacattta tacatattaa
    11341 attcttatat attaaatttc tatgcatcac ttttatacat attaaattcc tatatattaa
    11401 acttttatgc gtcactttta tacatattaa attcctatat attaaacttt tatgcatcac
    11461 ttttatacat attaaattct tatatattaa acttttat
//
LOCUS       DAMJYN010000102        11440 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.106, whole genome shotgun sequence.
ACCESSION   DAMJYN010000102 DAMJYN010000000
VERSION     DAMJYN010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11440)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11440)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11440
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.106"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            9..350
                     /locus_tag="PC466_003163"
     CDS             9..350
                     /locus_tag="PC466_003163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2770521.1"
                     /translation="MSNNKICDVICVHEEKVNYALRFLKEEKTQRLINILLKISDENK
                     LKIILALIKEKELCVCDLSITLGLSIASTSHHLRALYKRDVLNFYKDGKMAYYYIKDI
                     EMKSLLIKCMT"
     gene            complement(370..771)
                     /gene="arsC"
                     /locus_tag="PC466_003164"
     CDS             complement(370..771)
                     /gene="arsC"
                     /locus_tag="PC466_003164"
                     /EC_number="1.20.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011461622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase (thioredoxin)"
                     /protein_id="HDF2770522.1"
                     /translation="MNKKTIYFICTGNSCRSQMAEGWGKKILGEDWNVYSAGIETHGV
                     NPKAIEAMKEVDIDISNHTSDLIDSDILEQSDLVVTLCSDADDNCPILPPNVKKEHWG
                     FDDPAGKEWPEFQRVRDEIGKRIQAFKETLV"
     gene            complement(789..2078)
                     /gene="arsB"
                     /locus_tag="PC466_003165"
     CDS             complement(789..2078)
                     /gene="arsB"
                     /locus_tag="PC466_003165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020375637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenite efflux transporter membrane subunit
                     ArsB"
                     /protein_id="HDF2770523.1"
                     /translation="MTILAIIIFLLTLIFVIWQPKGLDIGITALIGAVVAIVTGVVSF
                     SNVLEVTGIVWNATLTFVSVILISLILDEIGFFEWSAIHMVKASNGNGLKMFVFIMLL
                     GTIVSAFFANDGAALILTPIVLAMVRNLGFNKKVIFPFIIASGFIADTTSLPLIVSNL
                     VNIVSADYFDIGFIEYFSRMIIPNIFSLIASILVLWLYFRKSIPNTFDTENLTDPKNA
                     IKDPKLFKISWIVLAILLVGYLVSEFIQIPVSIIAGIIAIIFLLLARKSKSVHTKQVI
                     KGAPWNIVLFSIGMYLVVFGLKNVGITTILADVLSNISSHGLFSSVMGMGFISAFLSS
                     IMNNMPTVLIDAIAIGQSNVVGTIKEGMVYANVIGSDLGPKITPIGSLATLLWLHVLT
                     QKGVKISWGTYFKTGIIITIPVLFITLLGLYLTLIIF"
     gene            complement(2078..2392)
                     /gene="arsR"
                     /locus_tag="PC466_003166"
     CDS             complement(2078..2392)
                     /gene="arsR"
                     /locus_tag="PC466_003166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="As(III)-sensing metalloregulatory
                     transcriptional repressor ArsR"
                     /protein_id="HDF2770524.1"
                     /translation="MSYKELSAIFKVLSDPSRLEILDLLSCGELCACDLLEHFQFSQP
                     TLSHHMKLLVDNKLVTTRKDGNKHWYQLNHAILDDIIQNLNIINTSNQRCVCKNVKSG
                     DC"
     gene            2597..2797
                     /locus_tag="PC466_003167"
     CDS             2597..2797
                     /locus_tag="PC466_003167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002473361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770525.1"
                     /translation="MRINHAGTLSVDYFVSYLNLIMRSREVSLKEAISYMKNEFFKGE
                     PEMYGKITETHFNQAIQELKQK"
     gene            2830..3150
                     /locus_tag="PC466_003168"
     CDS             2830..3150
                     /locus_tag="PC466_003168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002449352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HDF2770526.1"
                     /translation="MEIIKSSPNRSEEEKLDFYEQMFNALADKIRLKILQSIRQSDSK
                     SLCVCDLEELLALKQSKLSYHLKKLVDANILIAEKHGTWNYYKINEQQIQVVLNEDTC
                     CKIL"
     gene            3240..4124
                     /locus_tag="PC466_003169"
     CDS             3240..4124
                     /locus_tag="PC466_003169"
                     /inference="COORDINATES: protein motif:HMM:NF015715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HDF2770527.1"
                     /translation="MIDSIMEFIKTFLMLFFELLLLFIVVSFIVSLIQQVVSEEKIKK
                     LLSKPNKAVNYILGMVFGAVTPFCSCSTIPILAGLLNSKVPFGPAMSFLIASPLMNPL
                     MIFMLWALLGWKVAIVYFVVLAIFSILTGLVFSKMNLAESYKGVNVKGDGFFANKTGS
                     RFKQALNDAWAFLYPMLPYLFIGVFIGAFIYGFIPEEFITKYASGDGFISVFIASVIG
                     IPMYIRPETMLPIAKALVSKGMSLGTVVALIIGGAGASIPEVVLLSKLFKKKFVISFI
                     IAILIVAIATGLIVNIII"
     gene            4138..4275
                     /locus_tag="PC466_003170"
     CDS             4138..4275
                     /locus_tag="PC466_003170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016898846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770528.1"
                     /translation="MGIKDALKKIKPQEQSCCSVEIEEKNEKKEKDEKEQEDNNNCCN
                     K"
     gene            complement(4409..4588)
                     /locus_tag="PC466_003171"
     CDS             complement(4409..4588)
                     /locus_tag="PC466_003171"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770529.1"
                     /translation="MSNIIKTIGKGIGKGVGAAAGLGILGSYFKRTFTIKGPLGKEIT
                     RIIENHFSEPVEIKA"
     gene            complement(4768..4863)
                     /locus_tag="PC466_003172"
     CDS             complement(4768..4863)
                     /locus_tag="PC466_003172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001801861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HDF2770530.1"
                     /translation="MILIFVHIIAPVISGCAIAFFTHWLSKCNKK"
     gene            complement(5190..6056)
                     /locus_tag="PC466_003173"
     CDS             complement(5190..6056)
                     /locus_tag="PC466_003173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002440631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HDF2770531.1"
                     /translation="MSGETVVYKNDLNLVPLRKFTSIEINLFFAMCNKLKEQDTYTLH
                     LTFDELKELSNYNPKTRNISRFVKDLDDVYKKMLELTIKYEDDDIIERFVLFNHYRIH
                     KKEQYLEISTSPNLKHILNSITNNFTKFELEEMTTLKSTYSKNMFRILKQFKHTGYLK
                     MKINDFRERLDIPTSYRMTDINKNVLKPIINELSYIFKALKIHKVRAKKGRKIEYLEF
                     IFEPENRIYNKKYAKSKNTVGSKQYISREKTPQWLEERSYEKTPISEEHDPELEKERE
                     AFLKQLQIDWDE"
     gene            complement(6932..7264)
                     /locus_tag="PC466_003174"
     CDS             complement(6932..7264)
                     /locus_tag="PC466_003174"
                     /inference="COORDINATES: protein motif:HMM:NF014505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HDF2770532.1"
                     /translation="MVNLYDVIKLDFNPVIGTEKGNYRPCLVISDTEFNKVSGFAWVI
                     PITKRYDERYPTDVLVKTKNQHINGFIDCTQIKSVDIHARPYRYLDISTTEKVIEVND
                     RLKSLLNL"
     gene            complement(7258..7506)
                     /locus_tag="PC466_003175"
     CDS             complement(7258..7506)
                     /locus_tag="PC466_003175"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770533.1"
                     /translation="MKTTYAKIYKIGNGQAISLKKNILQQVGLKVGDDIEVKVKSGQI
                     VLTKPNSFKEKWRDFVESGGKYDHNKYDWGQSVGRELW"
     gene            complement(9485..9706)
                     /locus_tag="PC466_003176"
     CDS             complement(9485..9706)
                     /locus_tag="PC466_003176"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDF2770534.1"
                     /translation="MATLPKEVRQKLESNIHIYKVNSKNIYYTDEFKLKIVEEYNHGK
                     EPEDIFRDAGIDVNILSQYRNEKHIEGRL"
     gene            9878..10684
                     /locus_tag="PC466_003177"
     CDS             9878..10684
                     /locus_tag="PC466_003177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019236258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HDF2770535.1"
                     /translation="MEIITFAAVKGGVGKTTLSYNFSAYLADLGYKVLMIDFDHQCNL
                     SQILGIYDQKNTVLSIFEKIDALHIEEKVKIHHINNNIDLISGFLRLDEYEKHMSTTD
                     GKDMQLYMWLDDYYEEYNIGQYDYIIIDTHPDFSTSTRNAIVVSHKVISPNKPSGFSD
                     DSNANISYRINKLKKDLIDFRTRESYVTAKLFFVGNMVKHNTKSSINFKKSIENQENY
                     ITYFPDKELITRSVLEKKPIVSFKQEPTIYLKEKSFFQQFINSCKAIKDA"
     gene            10793..11050
                     /locus_tag="PC466_003178"
     CDS             10793..11050
                     /locus_tag="PC466_003178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002467476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HDF2770536.1"
                     /translation="MAFNKKIDSNNQENNIEKALENAVSPNTSYKKIEIKKDKIKEKK
                     KRYQFMLQPSVRKKLDELVEENNYSSSSEFLNEIIKQLYVN"
BASE COUNT         4095 a         1655 c         1628 g         4062 t
ORIGIN      
        1 gacttaatat gagtaacaat aaaatttgtg acgtcatttg tgttcatgag gaaaaagtga
       61 attatgcttt aagattttta aaagaagaaa aaactcaacg gcttatcaat atattattaa
      121 agataagtga tgagaataag ctgaaaatta tattagctct aattaaagag aaagaattat
      181 gtgtttgtga cttatctata acattaggtt tgagtatagc ttcaacatca catcatttga
      241 gagccctgta taaaagagac gtgctgaatt tttacaagga tgggaaaatg gcatactatt
      301 atatcaaaga tatagaaatg aaatcattat taataaaatg tatgacttaa atataaagaa
      361 acgctcacat taaacgagcg tttctttgaa tgcttgtatt ctttttccaa tttcatctct
      421 aacacgttga aattctggcc attcttttcc tgctggatca tcaaagcccc agtgttcttt
      481 tttaacatta ggtggtaata tagggcaatt atcgtctgca tcactacata atgttacgac
      541 caaatctgac tgttctaaga tatcactatc aatcaaatct gatgtatggt ttgagatatc
      601 aatatccact tctttcatag cttctattgc tttaggatta acaccatgag tttcaatacc
      661 agcagaatag acattccaat cttcacccaa tattttcttt ccccaacctt cagccatttg
      721 gctacgacaa gagtttcctg tacatataaa ataaattgtt ttcttattca taattacatc
      781 ctcttttctt aaaatatgat tagtgtaagg tataaaccta agagtgttat aaataggact
      841 ggaatagtaa tgataattcc agttttaaag tatgttcccc atgaaatctt cacacctttt
      901 tgtgttaaga catgtaacca caataatgtt gctaaagaac caattggcgt aattttaggt
      961 cctaaatcag aaccaattac attcgcataa accatacctt ctttaatagt acctactaca
     1021 ttagattgtc cgatagcaat agcgtctatt aaaaccgtag gcatattatt cataattgat
     1081 gataaaaatg ctgatataaa gcccatgccc ataacactgc tgaataatcc atgacttgaa
     1141 atattggata atacatcagc taaaattgtt gtgattccta cgttttttaa accaaatacg
     1201 actaagtaca taccaataga aaatagaacg atgttccatg gtgcgccttt aatcacttgt
     1261 tttgtatgaa ctgatttaga tttacgagct aacagtaaaa agataatagc aataatacca
     1321 gcaatgattg atacaggaat ttgaataaac tcactaacaa gatatcccac tagtaatatt
     1381 gctaatacaa tccatgaaat cttaaataat ttaggatctt taattgcatt tttaggatct
     1441 gtaagatttt ctgtatcgaa cgtgttaggt atagattttc tgaaatataa ccataaaacg
     1501 agaatactag caatcagaga gaatatatta ggaataatca ttcgactaaa atattcaata
     1561 aatccaatat cgaagtaatc tgcagaaacg atattaacta agttacttac aattagaggt
     1621 agtgatgtag tatcagcaat aaaaccactg gcaataataa aagggaaaat cactttttta
     1681 ttaaatccta gatttcttac catcgctaat acaatgggcg ttaagattaa agctgcacca
     1741 tcatttgcga aaaatgctga tacaattgtc ccgagtagca ttataaaaac aaacattttt
     1801 aatccattac cgtttgaagc cttgaccata tgtatcgcag accattcaaa aaatccaatc
     1861 tcatctaata ttaatgaaat aagaataaca gatacaaatg ttaatgtagc attccaaaca
     1921 atacctgtta cttctaatac attggaaaaa cttacgactc ccgtaacgat agcaacaaca
     1981 gctccaatta aagctgtaat accaatatct aaaccttttg gttgccatat cacaaagatt
     2041 aaagttaaca agaagattat aattgctaaa atggtcatca acagtcacct gatttcacat
     2101 ttttacatac acatctttga ttagatgtat taatgatgtt caagttttga ataatatcat
     2161 ctaaaatagc atgattaagt tgataccaat gtttgttgcc gtcttttcgt gttgtaacta
     2221 atttgttatc tactaataac ttcatatgat gacttagtgt aggttgtgag aattgaaaat
     2281 gttctaataa gtcacaagcg catagctcac cacaagaaag taaatctaat atttctaacc
     2341 tgcttggatc tgataaaact ttgaatattg ctgataattc tttataagac ataaatatac
     2401 ctccttttca ttacatagat taacatctat atagctttat gtctatgtag ttttttgact
     2461 aattttagta ttagattaga atgcgtccta aataactagt tttattatct tgcaaaagtt
     2521 gaaataataa tttatattta atacatcaaa aaaaattgat atatcatttt agtattttat
     2581 aaaggagttc gattttatga gaataaatca tgcaggtaca ttatctgttg attattttgt
     2641 tagctactta aatttaatta tgagatcaag agaagtttct ttaaaagaag ctatatcata
     2701 tatgaaaaat gagttcttta aaggagaacc tgaaatgtat ggtaaaataa cagaaactca
     2761 ttttaatcaa gcaatacaag aactcaaaca aaaatagaaa tatctatata taagagaggt
     2821 gattatttaa tggaaattat taagtccagt cctaatagaa gtgaggaaga aaaattagac
     2881 ttttatgaac agatgtttaa tgcactagct gataaaatca ggcttaaaat tctacaatca
     2941 atacgtcaaa gcgattcaaa atctttatgt gtttgtgatc tagaagaatt attagcgtta
     3001 aaacaatcta aactttccta tcatttaaaa aaattagtag atgcaaatat tcttattgct
     3061 gaaaagcatg gcacatggaa ttattataaa attaatgagc aacaaataca ggtggtttta
     3121 aatgaagata cttgctgtaa gatactttaa gtatcttctt tataacatat aattaatcaa
     3181 ttttttttga ttaatacatc aagaaaagtt gattaaatga attcggaggc attatactaa
     3241 tgatagattc aattatggaa ttcataaaaa catttctgat gttatttttt gaattattat
     3301 tactatttat agtagtgagt tttatagtaa gtctgattca acaagttgtt tcagaagaaa
     3361 aaattaaaaa gcttttgagc aaacctaata aagctgtcaa ttacatatta ggtatggtgt
     3421 ttggtgctgt tacaccattt tgttcttgtt caactattcc aatacttgca ggtctattaa
     3481 attccaaagt tccttttggt ccggctatga gttttttgat tgcttcacca ttaatgaacc
     3541 cattaatgat atttatgtta tgggctttat taggatggaa agtagccatt gtttattttg
     3601 tagtactagc aattttcagt attttaacag gtttagtatt ttcaaaaatg aatttagctg
     3661 aaagttataa aggggtcaat gttaaaggtg atggcttttt tgctaataaa acaggatctc
     3721 gttttaaaca agcattaaac gatgcatggg catttttata cccaatgtta ccttatctat
     3781 ttattggtgt atttattggt gcctttatat atggattcat acctgaagaa tttataacta
     3841 agtatgcaag tggtgatggt tttatatcgg tgtttattgc ttctgttatc ggtatcccta
     3901 tgtatatcag accagaaaca atgttaccta tagccaaagc attagtatca aaaggtatgt
     3961 cgctaggaac agtagttgca ttaataattg gtggtgctgg cgcaagtatt ccagaggtcg
     4021 tattgctatc taagctattc aagaaaaaat ttgtaatatc attcattatt gcaattttaa
     4081 ttgtagccat tgctacaggt ttgattgtga atatcattat ttaaaggagg tgaaataatg
     4141 ggtattaaag acgcattaaa aaaaataaaa cctcaagaac agtcatgttg ttcggtagaa
     4201 attgaggaaa agaacgaaaa aaaagaaaaa gatgaaaaag agcaagaaga taataacaat
     4261 tgctgtaaca agtaatataa gggcctggaa tttatatcta ggcccttata ttaatctatt
     4321 ttgctacgct tttctatatt tattctacaa taattaaaaa aggacacatt ttgaaatcaa
     4381 tgtgtctttg aaaatggtta cctctatatt atgctttgat ttctacaggt tcactaaagt
     4441 gattttctat aattcttgtt atttctttac ctagtggtcc ttttattgtg aaagttcttt
     4501 tgaaataaga acctaaaata cctagacctg ctgctgcacc gacacctttt ccaatgcctt
     4561 tgcctatcgt ttttatgatg ttactcatga accaattaag agtatttaga tatcatctct
     4621 tcttaatcac tattatttct taaattttgc atttctttac ttaccagtgt tataattttg
     4681 gtaacgaaaa taagtattca cttatacacc aatcccctca ctattgcgag tagtgcgggg
     4741 atttttgttg gtgtggctat atgtcaccta ttttttattg catttactta gccaatgagt
     4801 aaaaaacgca atggcacagc cactgatgac tggcgctatg atgtgaacga aaataagtat
     4861 cactttatac acctcctctc tgcgtctgaa ttgacgcctg agagataggc aacctttata
     4921 ttataccatc tgtaatggat gagttacaga taacttccga taagccatct tatttatata
     4981 aaacctatat tatcatcgtg gtcaaaatgg gtggacttgc tatttatctt aaattctttt
     5041 tcatttttta aattttattc gataactttg atagaaatag gaagattgat tttgcctctt
     5101 ttacttttac cattgactaa tcatagatag cccataaaag cgccacacct ttaacacatt
     5161 gtatagctct acagtagcta tcataaatgt tactcatccc aatcaatttg tagttgcttt
     5221 aagaaagctt cacgctcttt ctcaagttca ggatcatgtt cctctgagat aggtgttttt
     5281 tcataagaac gttcttctaa ccattgtggt gttttttctc tactaatata ttgttttgaa
     5341 cccactgtat ttttactttt agcgtacttt ttattataga tacgattttc aggttcgaat
     5401 ataaattcta ggtattctat tttgcgtccc ttttttgctc taactttatg tatctttaat
     5461 gctttaaaaa tataactgag ttcgttaata ataggtttta atacattctt attaatatcg
     5521 gtcattctat acgatgttgg aatatctaat cgctctctaa aatcatttat tttcattttt
     5581 aaataacctg tatgtttaaa ctgcttaagt attctaaaca tgtttttaga atacgttgat
     5641 ttaagcgttg tcatttcttc tagttcaaat tttgtaaaat tattcgtaat tgaattaagt
     5701 atatgcttta gattaggaga tgttgaaatc tctaaatatt gttccttttt atgaattcta
     5761 taatgattaa acaacacaaa gcgctctatg atatcgtcat cttcatactt aattgttaat
     5821 tccaacattt ttttatatac atcatccaaa tctttcacaa atctactaat attacgtgtt
     5881 ttaggattat aattacttaa ttcttttaat tcatcaaaag tcagatgtaa cgtgtaggtg
     5941 tcttgttctt ttaacttatt gcacatcgca aaaaacaaat taatttctat gcttgtaaat
     6001 tttcttaatg ggacgaggtt tagatcgttt ttatatacaa ctgtttcacc agacatttta
     6061 ttatcactcc atcattaact acatcatata aaggagtact aaaaaaatga atactccttt
     6121 ataccaattg aatataagca taaaacactt ttatagcggc gtcaatgaat aaaaggagtg
     6181 attatattta aactactccc tttatgtggc aaaaacactc cttttatgtg gcaaaactac
     6241 tccttttatg tggcaaaact actcctttta tgtggcaaaa ctactccctc taataccttg
     6301 aatccattgt ctctctaggt ataaaacaat ccctaaaaag gttttaaaaa tatttataaa
     6361 aatatattaa aaagggcgac gtttataaga cagtagtcac gatgaaaaaa gatttgtaaa
     6421 taccatgtta catacattta tacttatact gttatttata tgtgtatcat cacatcacta
     6481 ttgtacaatt taaagtacgt tataatgatt gaagctttat gtaaaatagg tatattaatg
     6541 attttaaaat tattttcgct tcacagaaat tgattaaaac gttaaagcaa accaaaacat
     6601 gaaggtagta cagtttggat taataaaaaa catcaactcg aagtatagac gtatctccta
     6661 agcatacatc tatagaaaaa tataagtctt atgattatat tggtggattt gaaagtttat
     6721 tcatgaaaat agaaagggaa taactttcta atgttggact agtccacatt tatgcattca
     6781 tcttaataaa tacataaatg aagcaattat tattgccctc gtacctataa acgagggctt
     6841 atttttttga cttcgaatca ttagagaatc taaagcacaa aaatgatgat cccttcatca
     6901 ataatgatta gaggacttat catttttaat ttcatagatt taataaactt ttcaatctat
     6961 catttacttc tattaccttt tcagttgtcg atatatcaag atatcgatat ggacgagcat
     7021 gtatatcaac agatttaatt tgtgtgcagt cgataaaacc atttatatgt tgatttttag
     7081 tcttcactaa tacatctgtt gggtatcgct catcgtatct ttttgtaata ggaataaccc
     7141 aagcaaaacc ggaaacctta ttaaattcag tatcacttat gactaaacaa ggacgatagt
     7201 ttcctttttc agtaccaatg actggattaa aatctaattt aattacatca tatagattta
     7261 ccataattca cgtccaactg attgacccca atcatacttg ttatgatcat atttgccacc
     7321 gctttcaaca aaatctctcc atttttcttt aaaagaattg ggtttggtta aaacaatttg
     7381 tcctgatttg acttttactt ctatatcatc gccaactttt aatcctactt gctgtaatat
     7441 atttttcttt aagctaattg cttgtccatt tccgatttta tatattttcg catatgttgt
     7501 tttcataaaa tacgcctccg ttagtattta catgtcttta cataagttat agcatgttta
     7561 cattgattta ccattatctt atcctgcttc aaattcaata tacgacacaa tgcatcagtg
     7621 ttcattgtta aactctccgt aattttttga ttttgttcta actctaattg aaatcaatat
     7681 aatttttcgg tactatctaa cgttaatttg ttcagttggc gttcgccact tcgtaaacgt
     7741 tgaatacttg atgccgtcac acctgttttt tgatgaatat aatacgcaga taaatcgcta
     7801 tttaggagtt tttcaattgt ttcgataatt atattaaatg agtgaaacgt ttagaaaata
     7861 ctaaaagtaa aagattatga ataaggctaa ggcgataaca gaaacaccta tcatatagtt
     7921 acagaatatt ttgattttga ttcgattaat ttttgtcatt tttatcacct cattttatag
     7981 ttgaggtaag ggaggagaat atccctcgat tacctaatga atataactta atattagctt
     8041 gaatgtcagt tggcatgcag taaaggagac agtgcttttt ttattgattt tgaacataaa
     8101 aaagatgacc atcgcaacag tcatctaaag tacactcttc agatatgcac cgcaatttga
     8161 tatttatcat aacatgcaat tcatacttaa cggacttata tggacggctg agagggttta
     8221 aaattcaaat tcatattgtt ttttctgccg tcgacaattt tatatatttc aaaccgtgat
     8281 tcgatgtttc tgatgtcctc agccacatat ttgaatatct tttcattgat atctttcact
     8341 gtatacgttt aacaaatgtt aaatatcagt atgaacgcgg tcactaaatt caaaaagaat
     8401 taataaaaga gggacttatt gattttactt caaaaatgga taaacaacgt ctttacatct
     8461 atatgtctaa aatcaaggat caccaattct attattataa taaagaaaag aaatccaaca
     8521 aatacacata tgaccgtttc atagatgtat tgaacatcaa atcaaagcat acactaaaac
     8581 atattaatac cctagtgaaa cacaagctat taatcgtgag caatgtagga actacaattt
     8641 aagatataaa tgttgaacaa aatgagtcaa agaatgtaga tattaaatta cacaataata
     8701 agaataatcc atctgattca cacaatatgc atttagtaac actataaaca taatcaactc
     8761 tagggaacaa attattgcct tgaagatttg aagagtgaaa ttgaagaaat cttaatccgt
     8821 gtaaatcgaa aatagaaaat acacaacaaa acgattacca aagtatatac ttatctattt
     8881 ataagtatca aaggagcatt tactcaaaga tacgaagaag attataacag aggtgttatt
     8941 acaaaaagtc caaaaatggc tttatttgga gatccacaga atattgtgac tgtgctaatt
     9001 aaatctatga ttaatagata atacaagttt tatataagac cctgagttgc agaaataaaa
     9061 tgatttatct aagttaataa tttttaattg aaatatagat gcacacaaac atacacatca
     9121 atatattggt gtgtatgttt gtgtgctgtc cgtcttactt tatttaaagg gaaaccgtat
     9181 atattattac tgaaactaag taataacaaa atataaaggc ttatattttg tttactgttc
     9241 taattattcc ttcttttgtt agatcaataa tagactgata tttttcttta gtaagatcta
     9301 gtttgcttat ttcaattttt tctaattctt caattatgtg ctttccttga gacagtattt
     9361 tagagtatat agctatttca gatggttctt tttgtggttt aaaggcggat gcatcttcat
     9421 ttaattcttt ttctaaagta gttgaaatat catcagtaat attaatttgc tgactattcc
     9481 atttctataa tctgccctct atgtgttttt cattacgata ttgtgaaaga atatttacat
     9541 ctattccagc atccctaaat atatcttcgg gttctttacc atgattatat tcttctacaa
     9601 ttttaagttt gaattcatct gtataatata tgtttttact atttacttta taaatatgaa
     9661 tattagactc caatttttgt ctaacctctt tgggtaaagt tgccattttt ttctcctctt
     9721 ctttcttttt tatttcatta ctataaattg gttaaagtta aaatccaaaa tatatattta
     9781 tatcatgaat aaagagaagc ggaatttcga tatatactca tacatatgtg tatacatgtg
     9841 tgtatgttta tgttaaggtg gaaaaggagg tgtctaaatg gaaataataa cattcgcagc
     9901 cgttaaaggt ggagtaggaa aaacaacatt atcctataat ttttccgcat atttagctga
     9961 cttggggtac aaagtattaa tgatagattt tgatcatcaa tgcaatttat ctcaaatatt
    10021 aggaatttat gatcaaaaaa atactgtttt atctatattc gaaaaaatag atgcactaca
    10081 tattgaagaa aaagttaaga tacaccatat taataacaat atagatctta tcagtggatt
    10141 tttgcgttta gatgagtatg agaagcatat gagtacgaca gatggaaaag acatgcaatt
    10201 atatatgtgg ctggatgatt actatgaaga atataatatt ggtcaatatg actatattat
    10261 tattgataca catcctgatt tcagtacatc aacaagaaat gcaattgttg taagccataa
    10321 agtaatttct cctaataagc caagtggatt tagtgatgat tcgaatgcaa acatttcata
    10381 tcgtattaat aaattaaaga aggatttaat tgactttagg acacgagaaa gttatgtaac
    10441 agctaaactt tttttcgttg gaaatatggt caaacataat actaaatcat caatcaattt
    10501 taaaaaaagc attgaaaatc aagaaaatta tataacttat tttcctgata aggaattaat
    10561 tacacgcagt gttttagaaa aaaagccaat tgtatcattt aaacaagaac ctacaatata
    10621 cttaaaggaa aaaagttttt ttcagcaatt tataaatagt tgtaaagcta ttaaagatgc
    10681 ttgattagta caaagtaaaa agagtacttt aacttttact cacataagca taagtatata
    10741 taccaacatg tgtatgttta tgcacataat tcattatgaa aggcgtttta aaatggcgtt
    10801 taataaaaaa attgatagta acaatcaaga aaataatata gaaaaagctt tagaaaatgc
    10861 agtatcacct aatacatcat ataaaaaaat agagattaaa aaggataaaa ttaaagaaaa
    10921 gaaaaagaga tatcaattta tgttacagcc ttcagttaga aaaaaactag atgagttagt
    10981 tgaagaaaat aattattcat catcttcaga atttttaaac gagattataa aacaattata
    11041 tgtaaactag ttttacatat tatatttcag ataaatgaag ggaaagttaa gaaaacccta
    11101 ttaacaaaga atttgatttg ttaatagggt ttatttttgt gtttactcaa aaataaactt
    11161 gtaagtatat atataaataa gaacatcaat aaacttgtaa gtacttaata ttgaaatagc
    11221 aacttatatt attaagaaac acaatttaat gtcagtaaat aaaagaagat tgttaccaga
    11281 aaaaatagag atataaacat aacaaaatgc aaacgtgact ttgaataagg tagtaaagat
    11341 gatataccta ttaaagaaaa aaatgaaaca tttaacaact atgtacttta tgtcattatg
    11401 aaatgatatt tttgagatca ataaagagat attggataaa
//
LOCUS       DAMJYN010000103        11358 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.107, whole genome shotgun sequence.
ACCESSION   DAMJYN010000103 DAMJYN010000000
VERSION     DAMJYN010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11358)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11358)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11358
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.107"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            257..958
                     /locus_tag="PC466_003179"
     CDS             257..958
                     /locus_tag="PC466_003179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5058 family protein"
                     /protein_id="HDF2770537.1"
                     /translation="MKFQEMINSPGLWIVSSFLVIISVVQAIVFMKSALKEASNLGIE
                     RKGIKAAIRSASVTAIGPSLSPVITLLSLVAVIGAPTTWMRLCDVGAARTELGVISLT
                     SNLSGVEVGSAAFGAEAFSYALWGMALNNLGWLLVVFILGHRMRGIVEKMNVKYNPTW
                     VKKLLAGATVGLFAYLLSNQIKTFEIPKLTPAVISAIVMLVLTTLFKKNQRLQELSLG
                     IAMLIGMFGTQIVLS"
     gene            984..1640
                     /locus_tag="PC466_003180"
     CDS             984..1640
                     /locus_tag="PC466_003180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770538.1"
                     /translation="MYDKKMIKIGRISIGLAIIANFIPAIYVGLRFGQMPMLSVIFQI
                     WGLVATTYGVSWIVQPIAYYPTLGAPGSYIGWLAGSVGDIRMPAASMAQKIAGVEAGT
                     HEGEVVGTIGTCCSIFVSASMITIFTIVGYKVIPLLPEFITDSFNYILPALFGAIYVD
                     IARKDIRAGGCTIAVALAIMYFGEKIGIPGGLLTLFIVLGGILITRVFFVIDSNKTKE
                     "
     gene            1847..3487
                     /locus_tag="PC466_003181"
     CDS             1847..3487
                     /locus_tag="PC466_003181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacylase"
                     /protein_id="HDF2770539.1"
                     /translation="MFDVKIANGIIIDGTGNSRYKGDVGIVGDKIMAIGDLSQKEAKE
                     TIDATGKFVSPGFIDFHTHSDLSLVYDKYTRSRIHTGVTTDVIANCGIGVAPIREEKK
                     QELIDYLGTRIIGTIPIKLNLHWNTMQEYFDYLTENSPAVNVVAYVAQGPVRINEMGF
                     SKEPATLEQLKNMKLEVRKAMEAGCVALSSGLVYLPGAYTKKEEMAELCKELIPYNGY
                     YISHIRDEGDEEMEALDEAIYIAKTAGVPLHISHLKVMGHKNFGTIDKVFKKLDEAEA
                     DGLEVTFDCYPYTAGMTSLGALLPPWAFEGGVENMVKRLEVQENRDRIIKELEEGIPG
                     WQCFYQLAGGWDGVVLASVMTEANKYVEGKTLMEVAKINGENPFDTFFRLLIEEKSKI
                     QVVVHTQGQEDTDKVVCHPKSCIGSDSMDLSTEGLLSLGKPHPRAFGTFGRIFSYYVR
                     EKGMLTFEEAVKKITYLSAKRLGIYKERGLLKENYFADIVVFDPDTIEDKATYSNPKQ
                     YTVGVEYVLVNGKIALAGGKQTDVCAGRVIKNPLSIAK"
     gene            3846..5168
                     /locus_tag="PC466_003182"
     CDS             3846..5168
                     /locus_tag="PC466_003182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770540.1"
                     /translation="MKILYVGPGMVIDKILAVSKKNFPNIEADFLRYDRYIEVPDLLE
                     KYRGRVDAVLFTGKSPFKFFEKRQKDFVLSDYIPRHETTLYRVLLEITYLLKFDISRL
                     SIDTYDKAMLKRLYKEIGVEFKDEHMFFAEQKYLEEDYIKFVLEFHKYNYQNNDICCC
                     ITGLEEAYHAMKKENIPVVLALPSEDVMVQSIKNIQMRYIAKKNNENQIVVLAIKLNM
                     PSEYSLMKEDEYAYLSQRIKILDKLYHFNSRIDGVLVEQSRSEFMIFTTKKILELETK
                     KYRDIYLLDMIREVSVINTYIGIGYGKTANEAKFNAYESIKMAQSQKNDAAYVVFENG
                     EIMGPLKPNPAVKEKNSFDERFYQIATETGLSANTVYKVFNKIINSGKTEFTSKELAI
                     ICGVSIRTMDRIILRLCDSGYCEVVSEQLMSKYGRPSRILRFKPFLLF"
     gene            5365..6372
                     /locus_tag="PC466_003183"
     CDS             5365..6372
                     /locus_tag="PC466_003183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HDF2770541.1"
                     /translation="MGKYQDSKKVVRNYFEALENATGDEVENVLKQHMKSDYNWKGVY
                     PFREQEGTENVADVFWKPLKKSLSNMQRRQDIFIAGTNEIDNSEWVMSMGHFMGLFDK
                     DWLGIKHTRKMISLRYAEFNCVQDGKIAKTGLFVDIIGFMIQAGVNPLPPQTGSYFVY
                     PGPIDHNGLLFEDADEVEGVKTLALVNKMVDDLSELNESGTMGCPPEILKKSWAKDMI
                     WYGPGGIGASYTIPRYQEQHQLPFRNNLKGKTFNGHVCRFAEGNFACFFGWPNLTNVP
                     CGGFLGLPGGEVKADMQVVDVYYRKGDKLQENWVLIDIPYWLKQQGLDILERTKSIFN
                     A"
     gene            6410..7807
                     /locus_tag="PC466_003184"
     CDS             6410..7807
                     /locus_tag="PC466_003184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ester cyclase"
                     /protein_id="HDF2770542.1"
                     /translation="MASTNKNNVTSKEEEKEVSTSGLESCTVKENKAKMNQTNFSNIN
                     ENQTNENKTNTYKGNIDKINTNKSDINKVNIDTVDTDKLNTNTLTEKNKKVIFKGEDN
                     MSSTKIYYGDSLEVTPVGVMDYNDFSKQTKREQEIPGFDSKYRDFVDYIMKITHNIWE
                     EKGIGVIYDTYHNNVTMHCGSSNLVGIKDVISNTLQTLHAFPDRRLIGQNVIWSNFGA
                     DGFLSSHRVLSTATNLGDSNFGPATGRKINFRTVIDCATTNNRIHEEWLVRDNLWIVT
                     QLGLNPQEVAKSMAKASESKVLSLQSTYGICESMDGQFMPTKYQAKDDSVGEMMLEMT
                     SRIYNYKYINEVKKYYHDNAVVHFICDKDLNGYDEIQGMIVSLLASIPNGSYEVERVT
                     CNQREKNEGYDVSIRWRLRGINEGIGFFGQPSGKHIEVMGINHYHILQGKVKEEWITF
                     DGMDVLKQMYMGVEE"
     gene            7952..9217
                     /locus_tag="PC466_003185"
     CDS             7952..9217
                     /locus_tag="PC466_003185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2770543.1"
                     /translation="MKTTVEIENDIILGKDYSNLKRGIAFFSIALIYFFYCYNFMVGT
                     FIKPTMIYALADGGFGFSLKQTEEIFAVMSFGTIPGTFIFGVISTKIGKKRTLISVAL
                     LIGLTTFIPMLSPTDIMLWKIARLCTGVVLGGVFGTAMPLVADMFPSKYRGKLAAILT
                     ALFSLAMIFGGKVYGVLGDANWQILMYTAIIPPIVGAILAIFFVPDDLEYTKELVKKG
                     KETGEKISYISMYKGKYLWIGLGTILLSGANFTAYSAFSNNATTYLVTGIGMSAAVAG
                     SIYSLQGIGQLVGYLFWGSIADKFGRKIPFIGMALAAVFVFIYTKLGGDNTTTFYMIS
                     VLLGVAVGYSGAWGAYYTELFPSKYRSLSSGMSFNGGRIISTFAIPAIAGTASGTLGM
                     MTIFYISIAVFVAGAIVWLFLPETLNNKK"
     gene            9259..10298
                     /locus_tag="PC466_003186"
                     /pseudo
     CDS             9259..10298
                     /locus_tag="PC466_003186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432878.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
     gene            10333..11355
                     /locus_tag="PC466_003187"
     CDS             10333..11355
                     /locus_tag="PC466_003187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDF2770544.1"
                     /translation="MNQKKVHYNKSATSKDVARLAGVSQSSVSRAFGSANGKGVKPEV
                     RERIFRVANEIGYVPNLVARGMISGKTNVIGLIVGDSLGPFYNRIINLFVEKIQEIGK
                     QCLVFKVPRQQSIDSIISKVIQFQVEAVIITASAMNKVMAETCEENNIPVILFNRFIP
                     GIKISTVYVDPIEGGGMVAEYLLKKGHKNIGYIQFTRETSEEMEKKIGFYSKLRQSGI
                     HNLKEESANYDYDSGYEAGKRMLALSNPPTAIFCTSDLIAIGVMDAARFEYKLRVPED
                     LSVIGYDDIQMASWKSYNLTTIRQPLDLLIEKTINILKSLLNEENPESVVEMLKPELI
                     ERGSTL"
BASE COUNT         4092 a         1296 c         2282 g         3688 t
ORIGIN      
        1 aatgtcaaag taataaaata ccttataagt taattacagg ttaaaaaaat aatatgtgaa
       61 ttttctgata tttactaatt atcaataaag tatttaagta ttaatgtttt tagtgagact
      121 ttaagacaga taatctccta ttaaagatac tatatcttag ataaaataaa ttaaaacaat
      181 ataaaaacat aacaagatta cagaaagaaa gctcataata aaacactaaa aaatttattt
      241 taaggaggaa taaagtatga agtttcaaga aatgattaat agcccaggtc tttggattgt
      301 ttctagtttt ttagtaatta tttcagttgt tcaagcaatc gtatttatga aatcagcact
      361 taaagaggct tcaaatcttg gtattgaaag aaaaggaatt aaagcagcaa ttcgctcagc
      421 tagtgttaca gcaattggac cctctctatc tcctgttatt acattattat cactggtagc
      481 tgtgattggt gctcctacga cttggatgag gctttgtgat gtaggagctg ccagaacaga
      541 acttggagta atatctctta catcaaattt atctggagta gaagtaggta gtgctgcatt
      601 tggagcagaa gctttttcgt atgcactatg gggaatggct ttaaataact taggttggtt
      661 gcttgttgta tttattttgg gtcatagaat gcgtggaatt gttgaaaaaa tgaatgtgaa
      721 atataatcct acttgggtta aaaaactact tgcaggggct acagttggat tatttgctta
      781 ccttctttca aatcaaataa aaacattcga aataccaaaa cttacaccag cagttatttc
      841 agctatagtt atgctagtat tgacgacttt atttaaaaag aatcaacgat tacaagaatt
      901 atccttaggt attgccatgt tgattggtat gtttggcaca cagattgtac tatcatgatt
      961 aaaacagata agaggtgata attatgtatg ataaaaagat gataaaaata gggagaattt
     1021 ctataggtct tgcaattatt gcaaatttta ttcctgcaat ctatgtaggt cttcgctttg
     1081 gtcagatgcc aatgctttct gttatattcc aaatttgggg attagttgct acaacttatg
     1141 gagtgagttg gattgttcaa cctatagctt attatccaac actaggagct ccaggttctt
     1201 atataggttg gcttgcaggt tctgttggag atatacgtat gcctgcagca tcaatggcac
     1261 agaaaattgc aggtgtagaa gcaggaactc atgagggtga agttgtagga acaattggta
     1321 catgttgttc aatctttgta tcagcttcta tgattactat ttttaccatt gtaggctata
     1381 aagtaattcc tttgttacct gaatttatta ctgattcatt taattatata cttccagcat
     1441 tgtttggggc aatttacgtt gatattgcgc gtaaagatat tcgagctggt ggatgtacga
     1501 ttgctgtagc attagctatt atgtactttg gtgaaaaaat tggtatacca ggtggattgt
     1561 tgacattgtt tattgtgtta ggtgggatac ttattacaag ggttttcttt gtaattgata
     1621 gcaataaaac gaaagaatag gattgtttac taggaagaaa gactagaatt atttgctgag
     1681 aaaaagaata ggattgttta ctaggaggaa agactagaat tatttgctga gaaaaagaat
     1741 aggattgttt actaggagga aagactagaa ttatttgttg agaaaaaaga ataggattgt
     1801 ttattaagaa atatgaatat aaataagtct tgaaaggaga agaagaatgt ttgatgttaa
     1861 aattgccaat ggaataatca ttgatggtac aggaaattca agatataaag gtgatgtagg
     1921 gattgtagga gacaaaatca tggctattgg agatctaagt caaaaagagg ctaaagagac
     1981 tatagacgca actggaaaat ttgtatcacc tggttttata gatttccaca ctcattctga
     2041 tttatctctt gtgtatgaca aatacacaag aagccgtatc catacaggtg taacaacaga
     2101 cgttattgca aactgtggta taggagttgc tccgataaga gaagagaaga agcaggagtt
     2161 aattgactat cttggaacga ggataattgg tacaattcca ataaaattga accttcactg
     2221 gaatacaatg caggaatact ttgattactt aactgaaaat tctccagcag taaatgttgt
     2281 agcttatgta gcacaaggac ctgtacgtat caatgaaatg ggattttcaa aggagccagc
     2341 tactttagag caacttaaaa atatgaagtt ggaagttaga aaggctatgg aagctggatg
     2401 tgtagctctt tcgtcaggat tagtttattt accaggagca tatacaaaga aagaagaaat
     2461 ggctgaatta tgtaaggaat tgataccata caatggatac tatatatctc atattagaga
     2521 tgagggtgat gaagaaatgg aagctcttga tgaagcaatt tatatagcta agacggcagg
     2581 agttcctcta catatttctc atttaaaagt catgggtcat aagaattttg gaactattga
     2641 taaggtattt aaaaagctag atgaagctga ggcagatggc ttggaagtta cttttgattg
     2701 ttacccatat acagctggaa tgacatcttt gggtgcactt ttacctcctt gggcttttga
     2761 aggtggtgta gaaaacatgg taaaacgatt agaagtgcaa gaaaataggg acagaattat
     2821 aaaagagcta gaggaaggga ttcctggatg gcaatgtttc taccagttag caggtggttg
     2881 ggacggtgtt gtactagcct ctgtaatgac tgaagcaaat aaatatgtag agggtaaaac
     2941 tttaatggag gtagctaaaa tcaatggtga aaatccattt gatacgttct ttaggctttt
     3001 gattgaagaa aaaagtaaaa ttcaagtagt tgttcataca caaggtcaag aggatacaga
     3061 taaggtcgtt tgccatccaa agtcatgtat aggttctgat agtatggacc tttctacaga
     3121 aggcttactt tctcttggaa agcctcatcc ccgtgcattt ggtacttttg gacgaatttt
     3181 ctcttactat gttagagaaa aaggtatgtt gacttttgag gaagcagtta aaaagataac
     3241 ttatctttca gcaaaacgct taggaattta taaagaaagg ggtctactta aggaaaatta
     3301 ttttgctgac attgtggtat ttgacccaga tacaatagaa gataaagcga cttatagtaa
     3361 tcctaaacag tatacagtgg gagtggaata tgtattggta aatggtaaaa ttgcattggc
     3421 aggaggaaag caaactgatg tatgtgctgg acgtgtaatt aaaaatcctc ttagcatagc
     3481 aaaatagaat acattaagaa cttttataaa aatagtcttt ctttgaatat taaggaaggc
     3541 tatttttgtt aaattaataa agattactct acttgtgttt tctagagaat ttaactttaa
     3601 gtagaaaaaa caatatatta attgtaaaat gtaattaata ttaatggata agatttaaat
     3661 acaaaaactt aaatacaaaa atgttttaac agatagtcat aattaaaaaa cttaaagtaa
     3721 ctttttatat aagatataat tgattatgca aaattttatg aagcagcaac cttgttactt
     3781 taagtcaagg gaggttcaga aagtgtctta agagataata gtatctttag gaaaggagaa
     3841 acgaaatgaa aatactttat gtaggaccag gcatggtaat cgacaaaata ctagcagtaa
     3901 gtaaaaagaa ttttcccaat attgaagcag attttcttag atatgataga tatattgaag
     3961 tacctgattt attggaaaaa tatagaggta gagtagatgc agttcttttt acaggtaaat
     4021 cgccatttaa attttttgaa aaaagacaaa aagattttgt gttgtctgat tatattccta
     4081 gacatgaaac aacattatac agagtattgc ttgaaattac atatttgctt aaattcgata
     4141 ttagtagact tagtatagat acttatgata aagctatgct gaagagattg tataaagaaa
     4201 ttggagttga atttaaggat gaacatatgt tttttgcaga gcaaaagtat ttagaagagg
     4261 actacataaa gtttgtgctt gaatttcata aatataatta tcaaaataat gacatatgtt
     4321 gttgtattac aggtcttgaa gaagcatatc atgcaatgaa aaaagagaat attccagtag
     4381 ttttagcctt gccttctgag gatgtaatgg tacaaagtat aaaaaacatt cagatgcgtt
     4441 atattgcaaa gaaaaacaat gagaatcaga ttgttgttct tgctatcaaa cttaatatgc
     4501 cttcagaata ttcactgatg aaggaagatg agtacgctta tctttcacaa aggattaaga
     4561 ttcttgataa actataccat ttcaatagcc gtatagatgg tgttttggta gagcagagta
     4621 gaagcgaatt tatgattttt acaactaaaa aaatacttga gttagaaaca aagaagtaca
     4681 gagatattta tttgttggat atgattcgtg aagtttcagt tataaacact tatataggaa
     4741 ttggttatgg aaaaacagca aatgaagcta aatttaacgc ttatgagagt attaagatgg
     4801 ctcaaagtca aaaaaatgat gcagcatatg tagtttttga aaatggagaa attatgggac
     4861 cactaaagcc aaatcctgct gtcaaagaga aaaatagctt tgatgaacga ttttatcaaa
     4921 ttgctacaga gacagggcta agtgctaata ctgtatataa agtgttcaat aaaataataa
     4981 atagtggaaa aactgaattt acatcaaagg aattagctat tatatgtggt gtaagtatta
     5041 gaactatgga caggattata cttagattgt gtgattctgg ttattgtgag gtagtgagtg
     5101 aacagcttat gagcaagtat ggtagaccca gtagaatatt acgttttaaa ccttttctgt
     5161 tgttttaaat agatataagt taaaaattaa atttttatga taacattttc tttacaattt
     5221 tttagatata tgttaatatt tagaaaaatg catatgtatt cataaaataa actcaaaata
     5281 gctaaaaaat cattaaaaag gaaatcgtat gcataaaatg agaaagttaa tttataactt
     5341 aaataaatct gggaggagat aattatggga aaatatcagg attcaaaaaa agttgtaaga
     5401 aattattttg aagcattaga aaatgctact ggggatgagg ttgaaaatgt cttaaagcaa
     5461 catatgaaat cagattataa ctggaaaggt gtgtatccat ttcgtgaaca agaaggcact
     5521 gaaaatgtag cagatgtatt ttggaagcct ttaaaaaaat cattgagtaa tatgcaaaga
     5581 cgacaagata ttttcattgc aggaacaaat gagattgaca atagtgaatg ggtaatgagt
     5641 atggggcatt ttatgggact ttttgataag gattggcttg gcattaaaca tactcgtaaa
     5701 atgattagtt taagatatgc agaatttaac tgtgttcaag atggtaaaat tgctaaaact
     5761 ggattatttg tagatataat tgggtttatg attcaagcag gagttaatcc attgccacca
     5821 caaacaggtt catattttgt atatccaggg ccaattgacc ataatggatt actttttgaa
     5881 gatgcagatg aagttgaagg agtaaaaact ttagcattag taaataaaat ggtagatgat
     5941 ttatctgaat taaatgaaag tggtactatg ggatgcccac cagaaatact taaaaaatct
     6001 tgggctaaag atatgatttg gtatggtcca ggtggaattg gtgcttctta tactatacct
     6061 agatatcaag agcaacacca gctaccattt agaaataatt taaaaggaaa gactttcaat
     6121 gggcatgtat gtagatttgc agaaggtaat tttgcttgtt tctttggatg gcctaatctg
     6181 actaatgtac catgtggagg ttttttagga ttaccaggtg gagaggttaa agcagatatg
     6241 caagttgttg atgtttatta tcgtaagggc gataaacttc aagaaaactg ggtgttaatt
     6301 gatattcctt attggttgaa acaacaaggg cttgatattc ttgagagaac taaaagtatt
     6361 tttaatgctt agttatgcat acgtattcta aaacaaaggg ggatataaag tggcatctac
     6421 caacaaaaat aatgtaacaa gtaaagagga agaaaaagaa gtttctacaa gtgggcttga
     6481 atcatgtacg gttaaagaaa acaaagctaa aatgaatcaa actaatttta gtaatataaa
     6541 tgaaaatcaa acaaatgaga ataaaacgaa cacatataaa ggaaatatag ataaaataaa
     6601 cacaaataaa tccgacataa ataaagttaa catagataca gtggatacag ataaattaaa
     6661 tacaaatact cttactgaaa aaaataaaaa agttatattt aagggggaag ataatatgtc
     6721 atctacaaaa atttactatg gagattcatt agaagtaacg cctgttggag taatggatta
     6781 caatgatttt tcaaaacaga caaaaaggga acaggaaata cctggatttg attctaagta
     6841 tagagatttt gtagattata ttatgaagat tacacataat atctgggaag aaaaaggtat
     6901 aggtgttatt tatgatacat atcacaataa tgttacaatg cattgtggct cttcaaattt
     6961 agttggtatt aaagatgtta tttccaatac tcttcaaaca ttacatgcgt ttcctgatag
     7021 aagattaatt ggtcaaaatg taatatggtc taactttggt gctgatggtt ttttatcttc
     7081 tcaccgtgtt ttgtctacag caactaactt aggtgatagt aattttggac cagcaacagg
     7141 tagaaaaata aactttagaa ctgtaattga ttgtgccaca actaacaata gaatccacga
     7201 agaatggttg gttagagata atttatggat tgttactcaa ttaggattaa accctcagga
     7261 agtagcaaag agtatggcaa aggcaagtga atctaaagtg cttagcttac aatcaactta
     7321 tggtatctgt gaatctatgg atggtcaatt tatgccaact aagtatcaag caaaagatga
     7381 ttctgttggc gaaatgatgc ttgaaatgac aagccgtatt tataattata aatatataaa
     7441 tgaagttaaa aaatactatc atgataatgc agtagtacat tttatatgtg ataaagattt
     7501 aaatggttat gatgagattc aaggaatgat tgtaagttta cttgcatcaa ttccaaatgg
     7561 aagttatgaa gtggaaagag taacttgtaa tcaaagagaa aaaaatgaag gttatgatgt
     7621 atctataaga tggagattac gtggaataaa tgaaggtata ggattttttg gacagccttc
     7681 tggaaagcat atagaagtaa tgggaatcaa tcattatcat atacttcaag gtaaagtaaa
     7741 ggaagagtgg ataacttttg atggtatgga tgtattaaaa caaatgtata tgggagtaga
     7801 agaataaagc tgtttagagt ataaataatt ttgaaatgta tatagggaag tattgcttta
     7861 taaaatttaa gtggggaatg tatatgaaaa atagatgttt aaacttttag caaaaattat
     7921 gactaaattt aaaaggggga attataaaaa tatgaaaaca acggttgaaa tagaaaatga
     7981 tatcatatta ggaaaagact attcaaacct aaaaagagga attgcatttt tttcaattgc
     8041 tttaatatac tttttttatt gctacaattt tatggtgggt acttttatta aaccaacaat
     8101 gatttatgct ttagcagatg ggggatttgg cttttcatta aaacaaacag aagaaatatt
     8161 tgcagttatg tcttttggta caattccagg tacatttatt tttggggtga tttctacaaa
     8221 aattgggaag aagaggactt taattagcgt tgctttactg attggattga caacatttat
     8281 accaatgtta tctcctacag atattatgtt atggaaaata gcacgtttgt gtacaggagt
     8341 agtgttggga ggcgtatttg gaacagctat gcctttagtt gcagatatgt ttccaagtaa
     8401 atatcgtggt aagttagctg ctatattaac tgctttattt tcattagcaa tgatttttgg
     8461 tgggaaagta tatggcgttt taggtgatgc aaattggcaa atattgatgt atactgcgat
     8521 tataccacct atagttggag ctatcttagc aatcttcttt gtgccagatg atttggagta
     8581 tacaaaggaa ttagttaaaa agggaaaaga aactggtgaa aagattagct atataagtat
     8641 gtataaggga aaatacttat ggattggatt gggaacgatt cttttatcag gtgcaaattt
     8701 tacagcatat tcagcatttt caaataatgc aactacatac ctagtgacag gaataggaat
     8761 gtcagcagca gtggctgggt ctatatatag tttacaagga attggtcaat tagtaggata
     8821 tttattctgg ggttcaattg cagataaatt tggaagaaaa atacctttta taggtatggc
     8881 attagcagca gtatttgttt ttatatatac aaaattaggt ggagataata caacaacatt
     8941 ctatatgata tcagtattac taggtgttgc tgttggatat tctggagcat ggggagcata
     9001 ctacacagag ttgtttccaa gtaaatatcg ttcgttgtca tctggtatgt catttaatgg
     9061 aggaaggatt atatctacgt ttgcaatacc tgctatagct ggtacagctt ctggtacttt
     9121 aggtatgatg actatctttt acatatcaat cgcagtcttt gtagcaggtg ctattgtatg
     9181 gttattctta ccagagacgt taaataataa aaaataaaat actaggaatt tattttgtta
     9241 cttagaaagg ggtggcttat gatttcatca attgatgtat gtattataat aggatatttg
     9301 ctattaatgt tagttattgg ttattattca ggaaaagata ataaaaatca agaagattat
     9361 ttcttggcag gtaggtcaat gccatggatt ccaattgctt tatcagttgc agctactatg
     9421 attagtgcaa atggctttat aggtggtcct ggatgggcat atgtagatgg aatgtatcca
     9481 gtaatgtaaa atgtgcaaaa aattcttttg tagttagtgc atttgttatg aatttagttt
     9541 actactttat gctattggta ggagtaattt tatttgtttt ttatggggga aggacatttg
     9601 aaacttcaaa tgaaataatg attactttta ttttaaatga acttccagta ggagccattg
     9661 gaattattat tgcaggtgtg tttgcagcag caatgtctag tatcgactct atattaaaca
     9721 gtatgacaac tgtttttacg aaggatattt atgagtttta tttcaaaaaa gacaacaaag
     9781 aatcatcatt aaaagttaca atgattataa ctgtagttat aggagttgtt atgacaggtt
     9841 ttattattat gggatttgga ggaagcatca aatcaattct tgaccttgtt ggtaactata
     9901 tctcatactt tgctggacca gctacaggtg catttgtact agcaatgttt acatataaag
     9961 ctaatgataa aggagtatct attggtttta ttgtagggtt agttttagga ttttttattt
    10021 ctaataaata taatgtgagt tggttgtgga atccagcaat aggtgctaca ataacattga
    10081 tatttggata tatttttagt gtcattttaa agaaaaatca taaagtagat gatattaaaa
    10141 aatacactgc atttggtatg agaaatcacc ttatttctca aggaatggat aaagtagatg
    10201 gagtatctat agtgccattt tctttaggta aacaagaact aattgtatta gcttttttta
    10261 ttatccaata tattatatta tttttgatac aattttaaga agaaatacta gatatttaag
    10321 gagaaatact aaatgaatca aaagaaagtt cattataata aatcggctac atcaaaagat
    10381 gtcgcaagat tggcaggagt atctcaatca tctgtttcaa gagcatttgg tagtgcaaat
    10441 ggaaagggcg taaaacctga agtaagagaa agaatttttc gtgtagcaaa cgaaataggg
    10501 tatgttccta atttggtagc acggggaatg attagtggaa aaactaatgt tataggtttg
    10561 atagttggtg atagtctagg tccattttac aatagaatta tcaatttatt tgtagaaaaa
    10621 attcaagaga taggtaaaca gtgtctcgtt tttaaagttc ctagacaaca aagtatagat
    10681 agtataattt caaaagtaat tcagtttcaa gtagaagctg tgattattac agcttcggcc
    10741 atgaataagg tgatggctga gacttgtgaa gaaaacaata ttcctgtgat tctttttaat
    10801 cgttttatac ctggtataaa aataagtaca gtctatgtag acccaattga aggtgggggc
    10861 atggttgctg aatatctgct taagaaaggt cataagaata taggatatat tcaatttacg
    10921 agagaaacaa gtgaagaaat ggaaaagaaa attggatttt attctaagtt aagacaaagt
    10981 gggattcata accttaaaga agaatctgca aactatgatt atgattctgg atatgaagca
    11041 ggtaagagaa tgttagcatt atcaaatcct ccaacagcaa ttttttgcac aagtgacttg
    11101 atagctattg gtgtaatgga tgctgcaagg tttgagtaca agttgagggt gccagaggat
    11161 ttatcagtga taggatatga tgatattcaa atggcttcat ggaagagtta taatttaacg
    11221 acgattagac aaccactaga tttgttgatt gaaaaaacaa ttaacatact taagtcctta
    11281 ttaaatgaag aaaatccaga gtcagtcgtt gaaatgttaa aacctgaatt gattgaaaga
    11341 ggttctacac tttaagtg
//
LOCUS       DAMJYN010000104        10865 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.109, whole genome shotgun sequence.
ACCESSION   DAMJYN010000104 DAMJYN010000000
VERSION     DAMJYN010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10865)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10865)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10865
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.109"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            512..1372
                     /locus_tag="PC466_003188"
     CDS             512..1372
                     /locus_tag="PC466_003188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDF2770545.1"
                     /translation="MKIIQILNNNVALVKRGKNEIIVFVKGIGFKKRVGQVINENEIE
                     RTYILDSYDMLEHFSYLLQNSDSNNIVLINEIIEYGEKALNIKSSDYLSLTLLDHLEF
                     LLKRCEKNQFIKSPLVWNVKRFYPKHFEIGMHALKLIGDSKGINLPDDEAVSIALHFV
                     NMEVNKESHDSTIVELRTLADIVSIIKYHFNVELDETSTNYMRFTTHLQYFIQRIMSD
                     EASIDEDNSIDLYKQVSQLYPKSFGSVQKIRKYIKSQFNVDISISEETYLMLHINRVT
                     QRLEAKSDEI"
     gene            1362..3233
                     /locus_tag="PC466_003189"
     CDS             1362..3233
                     /locus_tag="PC466_003189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF2770546.1"
                     /translation="MKYKDLNENIIKLIGGKENIKSVAHCVTRLRLTLNDRSIAQTEE
                     IKKLKGVIDVVSNDVAYQIIIGTHVVDVYNEFMSMIGLSSSESSIKSERKKGIRGIKG
                     IFNSIFVVVSETMTSVIEVLLAAGILASILALLNMSGILQSDSPTYQILDTLRSATFH
                     FLPVLIAIASAKRLNVNPYIAVVLAVTLLSSSIDGVEGLSLFGINLQATTYANSFIPI
                     LLGVWAMGIIIEGLKKILPKALHYFLVPVLSLIITLSVTLTVFGPIGMWIGDGLNYAC
                     MFLIDTLGNWSVVALYAALQPLLIVFGAANFTMPISLNSVTTLGYDPIFMGAATISDI
                     AVCGAMFGYFLKTRNKEQKQLFGTVSFSALMGVTEPSVFGVFMKYRRPFVAVMIGGGI
                     GGLIAGLAQVKTYGMVWGLAALPTYLVGGEASNFTFMIISVVVSFVAATAASYLLGIP
                     SDEKEEVKGDNEKELELIINENNSRTISIGNVAKGQVIALGEVNDKAFSSGALGKGVG
                     VIPSESKSTVISPVDGTITIVFPTKHAYGIVTDEGLEILIHIGIDTVNLDGKFFESLV
                     TQNQRVKKGDALAVFESDKIIEEGFDSTIITVVTNTSDYLDVISSNDESEELLTVIV"
     gene            3253..4707
                     /locus_tag="PC466_003190"
     CDS             3253..4707
                     /locus_tag="PC466_003190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HDF2770547.1"
                     /translation="MNIKDTFFWGGSIAAHQCEGSWDSDNKGPAIMDFVTKGSYETPR
                     VITDKIEEKLDYPSHNGIDFYNRYKEDIALFKEMGFSALRISIDWSRIFPNGDDENPN
                     ELGIKYYEGLIDTLIENNIEPIVTLYHFELPMNLVHKYGSWNNRKLMDLYLKYSETVI
                     RRFDDKVKYWITFNEMNHIDPQTEHSDIFTYMIAGIKYSEIENKVQTLANVGYNMTLA
                     GVKVAKLAREINPNNKVGCVFGLNPIYPYNCNPSNVLNAFLDNDRDYYQIDAMCNGKF
                     PQYKLKEYEKNNITIEVTDEDKKAFKEGKLDFIGLNYYFSSVSTPKENLSGDKSLFGG
                     IQNPYLEQSKWGWAIDPIGLRFTLNYIYRKYQLPILITENGLGAYDKIEEDGTINDDY
                     RIEYLSKHLSQMKSAIEEDNVECFGYLMWGPIDLVSATTGQMSKRYGFIYVDLDDEGK
                     GSFKRYKKKSFDWYKEVIKSNGEVLDFSTDIVVG"
     gene            5731..6939
                     /locus_tag="PC466_003191"
     CDS             5731..6939
                     /locus_tag="PC466_003191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770548.1"
                     /translation="MENFWNPLTCFTVCVMIYAFSEFLSKKTKGAISTLLFVCIIFLL
                     GFWTNVLPKDITGASGILAAMSNFGIALLITNLGTLINLEDLCHEWKTVVIALVGIVG
                     IGVGCLTVGSMLFGREYALIAAPPIAGSTVAGIIVTTVAEAANRPELAAFVILVLSFQ
                     KFFGIPITTYCINKELKFKRDNGDFLKDESKSNFRLPSMRIFKEDLGKKSSTLVYLAK
                     LSFVAMIGNFVGLATLIPGFTPANYYLNPNIACLLVGLIFTRIGFLEKGILDKSQSNG
                     IIMFGCMLMLPGGLAKVTPTALFGMIVPTIGILVVGSVFIILFTAIVGKLLGYSPRMS
                     AAIGVTCMLAYPATQIISNEGIDAMEGTEEEKQRATDYLLPKMIIGGFVTVTIASVAF
                     ASIIGPIIFG"
     gene            6970..8349
                     /locus_tag="PC466_003192"
     CDS             6970..8349
                     /locus_tag="PC466_003192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2770549.1"
                     /translation="MIGSISINEIDKKRFKLDDLSKKIWENPEKAFKEFKACENTANF
                     LRSEGFDVEVGVGGLATAIRASFGSGKPVIGFMGEFDALPGLNQKVSTKQEAFELSAY
                     GHGCGHNLLCTAHVGAVVGLKREMLENNLSGTIVFYACPGEEQLTGKGFMARGGAFEG
                     LDLAINFHPNKISEATIGTSTAVNSVKFHFKGKTAHAGSDPQNGRSALDAVELTNVGA
                     NYLREHVTSDVRIHYTITDGGVAPNIVPDKASVWYYTRALSREAVESTYERLVKVAKG
                     AAMMTETEVEVEFLGGCYNTLNNHVLANLVSECMNEIKQEPWTREELDFAAELDRQSP
                     QQYKAMISKYNLPEGTHLYYGGGNVTNFNSYGSTDIGDVMHIVPTAYFFTGCTNLGAP
                     GHSWQFTSCAGSSIGEKGMIYASKIMAMFGAKILNNPEIAKKAKEEFDKSMNGKTYKC
                     PIPDDIPTP"
     gene            8455..9645
                     /locus_tag="PC466_003193"
     CDS             8455..9645
                     /locus_tag="PC466_003193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2770550.1"
                     /translation="MKNFFKEAQSIEGEIIRWRRYLHENPEIGCNLPKTVTFVTSTLE
                     KMGYSPKLTSNNGIVAVLDSENGGKTLLLRADMDALPIMEETDLPFKSKNKDASHSCG
                     HDNHTAMLLGAAKILMDNKHLLKGRVKFVFEPDEESTRGAKSMIDDGILENPQVDAAM
                     AFHSMVGKFLNTGQVAYSRGPAMASADIFEITVEGKATHGASPEFGVDPINIMSHIQI
                     ALNTILSREKPQKEPVVLTIGMFNAGNVPNAIPNKASMSGTLRTFDQFVREKLKNRII
                     EISTGIAKSFGGNAKVEFKMGTPAVINDLDVGDEIVSYVKEIIGNENVIDFPSAMGSE
                     DFSEILLRVPGVFLWIGMGSISQGYNFGMHNPKAIFNEEGLVYGSALFAHCAVKWLEN
                     NFSR"
     gene            complement(9773..10837)
                     /locus_tag="PC466_003194"
     CDS             complement(9773..10837)
                     /locus_tag="PC466_003194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770551.1"
                     /translation="MFLKLIFKYNTLDFSRAYFDLTDWADNPKDISYYLSNGTFGDLM
                     DSIDENASKMSLSDIAKLEKKIAKKHINLWNEGKIDFSTTRFSSIVPMLQNAGVNFHF
                     IYPDIDLLKNTFNNLIKDIHLHRMKGNQPSVIYITVKDTNYDDSTLDQVYKILNSIKK
                     DKLTDFIIEKNSNSFKIFTKCETIKSLTKNFTACYIKESIENSTNIKVCVGYGIGNDI
                     KQAMSSAISANKESKINPLNYSFLVNENYETIGPLLCDKLLTVSNKVTPHINTIAKSS
                     KLSTLTIQKIISVTEILQRDEVTPKELSSCLNVTVRTANRFLSSLLKSGNATILYEKQ
                     NSTKGRPERVYKLFISENKY"
BASE COUNT         4058 a         1209 c         1961 g         3637 t
ORIGIN      
        1 ttaaataaaa ctaaatttaa gtatttatat attagtatat cttaatagca tttaaataaa
       61 actaaatttg aagctttacc tattaatata tcttaatagt gattaaataa aactaaactt
      121 aagaatttat ttattaacat acagttcatt atatttaaaa tcattactat gataattcat
      181 aatagtaaaa tagataatgg ttcagacaat attgtaaata ttagtgacag taaaatagta
      241 tcaatttagt atataaactt tgccagataa tcgcataaca gagcttgtag ttatagaata
      301 aaaaaatatc taggaaaccg ttgacagatt tatatggata gtataacata tagaatatga
      361 aattaaacaa aaaagaattt taattatggc gacgtagtca taattttgag tatgttactg
      421 attagcaggc agaactcaag tatatatgtg aaaaatagag ggatactcta tacatatatg
      481 cttgagttct ttttattgaa aggaggaata tatgaaaata attcagattt taaataataa
      541 tgtagcctta gtaaaaagag gtaaaaatga aattattgta tttgttaaag gaattggctt
      601 taaaaaaaga gtgggacaag taataaatga aaatgaaata gagagaacat atatactaga
      661 ttcatacgat atgctagaac actttagtta tctactacaa aactcagact ccaataatat
      721 agttcttatt aatgaaataa ttgaatatgg tgagaaagct ttaaatataa agtcaagtga
      781 ttatctaagc ttaaccttac tagaccattt agagttttta cttaaaagat gtgaaaagaa
      841 tcaatttata aaaagtcctt tggtatggaa tgttaaaaga ttttatccaa agcattttga
      901 aattggaatg catgcactaa aattaattgg tgatagtaag ggaattaatc ttcctgatga
      961 tgaggcagta tcaatagcac ttcattttgt aaatatggag gtaaataaag agtctcatga
     1021 tagtacaatt gtagagttga gaactttagc agatatagtt tctataataa aatatcattt
     1081 taatgtagag ctagatgaaa cttcaacaaa ttatatgaga tttactactc atctacagta
     1141 ctttatccaa agaattatgt cagatgaagc ttcaatagat gaagataatt ctatagattt
     1201 atataaacaa gtaagtcaac tttatccaaa gtcatttgga agtgttcaaa agataagaaa
     1261 atatataaaa tcacaattta atgtcgatat atctataagt gaagaaactt atttaatgtt
     1321 gcatataaat agggtgactc aaagactgga ggcaaaatca gatgaaatat aaagatttaa
     1381 atgaaaatat aataaaactt atagggggaa aagaaaatat aaagtcggta gcgcattgtg
     1441 ttactcgttt aagacttact ttaaatgata gaagtatcgc tcaaacagaa gaaattaaaa
     1501 aattaaaagg agtaattgat gtagtttcta atgatgttgc ttatcaaatt ataataggta
     1561 ctcatgttgt agatgtatat aacgagttta tgtctatgat aggtttaagt tcaagtgaat
     1621 caagtataaa aagtgaaaga aaaaagggaa ttagaggtat caaaggtata tttaattcca
     1681 tctttgtggt agtctcagag actatgactt cagtaattga agtactactt gcagctggta
     1741 tactcgcaag tatattagca cttttaaata tgtctggcat acttcagagt gatagcccta
     1801 catatcaaat attagataca ttaagaagtg ctacatttca cttcttacca gtattaattg
     1861 caatagcatc agcaaaaaga cttaatgtaa atccctatat agcagtagtg ttagcagtta
     1921 cgttattatc gtcatcaata gatggtgtag aaggattaag tttatttggt ataaatttac
     1981 aggctacaac ttatgcaaac agttttattc caatactttt aggagtatgg gcaatgggaa
     2041 ttataattga aggtttgaaa aaaatattac ctaaagcact acactatttt ttagttccag
     2101 tgttatcttt aataataacc ctatcagtta cattaactgt atttggacct attggtatgt
     2161 ggattggtga tggattaaac tatgcatgta tgtttttaat tgatacattg ggtaattgga
     2221 gtgttgttgc actgtatgca gctttacaac cactcttaat agtttttggt gcagcaaact
     2281 ttactatgcc tatatcttta aattctgtga caacattggg gtatgaccca atttttatgg
     2341 gcgctgcaac aatatctgat attgcagttt gtggtgcaat gtttggatat ttcttaaaaa
     2401 ctaggaataa agaacaaaaa caattatttg ggacagtaag ttttagtgca cttatgggag
     2461 ttacagagcc ttcagtgttt ggtgtgttta tgaaatatag aagaccattt gtagcagtaa
     2521 tgataggtgg aggtataggt ggtttaatag caggtttagc tcaagttaaa acatatggaa
     2581 tggtttgggg attagctgca ttaccaacat atcttgttgg aggagaggca tctaacttta
     2641 catttatgat aataagtgta gtagtatcat ttgtagcagc aacagcagct tcctatttac
     2701 taggaatacc ttcagatgaa aaagaagaag ttaagggtga taatgaaaaa gaattagaac
     2761 taataatcaa cgagaacaat tcaagaacta ttagtattgg aaatgttgca aaaggtcagg
     2821 taattgcact tggggaagtt aatgacaaag cattttcctc tggagcatta ggtaaagggg
     2881 ttggagttat acctagtgaa tcaaaatcaa ctgttatatc tcctgtagat ggaactataa
     2941 ctatagtatt tccaactaaa catgcatatg gtatagtgac tgatgaagga ttagaaatat
     3001 taattcatat tggtatagat actgtaaact tagatggaaa attctttgaa agtcttgtaa
     3061 cacaaaatca aagggttaaa aaaggagatg ctttagcagt atttgaatct gataaaatta
     3121 tagaggaagg ctttgattct actataataa ctgtagttac aaatactagc gattatttag
     3181 atgtaatctc atcaaatgat gaatcagaag aattattaac tgtaatagta taaattttag
     3241 gagggaaaat tcatgaatat taaagataca tttttctggg gaggaagtat tgcagcccat
     3301 caatgtgaag gttcatggga tagtgataac aaaggacctg caattatgga ttttgtaact
     3361 aagggctctt atgaaacgcc aagagtaatt actgataaaa tagaagaaaa attggattat
     3421 ccatctcata atggaataga tttttataat agatataaag aagatatagc tttatttaaa
     3481 gaaatgggat ttagtgcatt aagaatatct atagattggt caagaatttt tccaaatgga
     3541 gatgatgaaa atcctaatga attagggatt aaatactatg aaggtctgat agatacatta
     3601 atagaaaata atatagaacc tattgtaaca ctatatcatt ttgaattacc tatgaattta
     3661 gtacataaat atggttcatg gaataacaga aaacttatgg atttgtattt aaagtacagt
     3721 gagactgtaa taagaaggtt tgatgataaa gtaaagtact ggattacatt taatgagatg
     3781 aaccatattg accctcaaac agagcactcg gatattttta cttatatgat agcaggtatt
     3841 aagtatagtg aaatagaaaa taaggttcaa acattggcaa atgtagggta taatatgact
     3901 ttggcgggtg taaaggttgc aaagttggct agagaaatca atcccaacaa taaagttgga
     3961 tgtgtatttg gactaaatcc aatttatcca tacaattgta atcctagtaa tgtgttaaat
     4021 gcatttttag ataatgatcg tgattattat caaattgatg caatgtgcaa tgggaagttt
     4081 ccccaatata aattaaaaga atatgaaaaa aataatataa ctattgaagt gactgatgaa
     4141 gacaaaaaag catttaaaga aggtaagtta gattttatag gtcttaatta ttatttttca
     4201 agtgtatcta ctccaaaaga aaatttatca ggtgataaat ctttatttgg tgggattcaa
     4261 aatccatatt tggaacaaag taagtgggga tgggcaatag accctatagg tttaagattt
     4321 accttgaact atatttacag aaagtatcaa ttacctatct taattacaga aaatggttta
     4381 ggggcatatg ataaaatcga agaagatgga actataaatg atgattatag aattgaatat
     4441 ttaagtaagc atctatctca aatgaagtct gcaattgaag aggataatgt tgaatgtttt
     4501 ggatatttga tgtggggacc aattgattta gtcagtgcaa ctacaggtca gatgagtaag
     4561 agatatggat ttatatatgt tgacttagat gatgaaggca aaggaagttt taagagatat
     4621 aagaaaaaat catttgattg gtacaaagaa gtaataaaat ctaatggaga agttttagat
     4681 ttttctacgg atatagtagt agggtagtaa taagataaat agaagttagg aactaatgtt
     4741 aattagtgtc tagtaaagca tttaaaatag agtatagggt ctttaaagta aagtgtgtat
     4801 tcttattaaa agtaatggca actaaaatta ctataaaaag gagaatacac attttttatg
     4861 tttatactta agtaaatatt tagacatatt catagtataa tttactcatt atataaaaat
     4921 agtatgattt actcactata taactttata aattttctag aaaaatgtca gaatatattg
     4981 acaaaaaaaa gatttgaaat tataatctat attgagaata gtttgacaat ataaaaacaa
     5041 gtatttttac aaatagtgaa attattttta ttgtcaattt aagaataatt taggactact
     5101 ataaagatga aggtatagat gtcattatat gataaatcat acttgtatag aaagaatttt
     5161 aaagtatgct tatcattgat ttaatataat aaataatttt tgtttctagt aatagttcat
     5221 aggaataaga tatctaaatt cgcttagaaa tagtctaatt tacaaaggag gggatgcact
     5281 agtagataaa atttttatat aaagaagact taaagtggag tatattctga taatattggt
     5341 ttaatggtta tattattatt tcgttttaga tattttaaga ataatttaag acgtttgtaa
     5401 aaatgtattc tatatctaat atttaaataa atataagtct tccaacatgt atactaagat
     5461 agaaagtagt tgaagtacaa ttctaacttg taaaattatg tagaaagtaa aaatcaaaaa
     5521 gaaatctagt aagttgataa ttatagttaa tatttagaga gttaactcta gttatattta
     5581 tttagatatt ttaggaataa tttaagacgt atataatatc atcaaaaaat atcaagctat
     5641 accatatgta gttaagaata actgcataat atacatttta taattattgt tttattgata
     5701 aaaaattatt atatttagga ggaaacaaca atggaaaatt tttggaatcc acttacttgc
     5761 tttactgtat gtgtaatgat ttatgctttt agtgagtttt tatctaagaa aacaaaaggt
     5821 gcaatttcaa cattgttatt tgtatgtatt atatttttac taggattttg gacaaatgtt
     5881 ttaccaaaag acattacagg agcatcaggg atattagctg caatgagcaa ctttggtata
     5941 gctttattaa taactaactt aggaacactt ataaatcttg aagacttatg tcatgaatgg
     6001 aaaacggttg taattgcatt agtaggtatt gtaggaatag gggttggctg tttaacagtg
     6061 ggtagtatgt tatttggtag agagtatgct ttaatagcag cacctccaat agcaggttct
     6121 actgttgccg gtattatcgt aacaactgtt gcagaagctg caaatagacc tgaacttgct
     6181 gcatttgtaa ttctagtatt atcatttcaa aagttctttg gcattccgat aactacatat
     6241 tgtataaata aagaattaaa atttaaaaga gataacgggg attttttgaa agatgagtca
     6301 aaaagtaatt ttagacttcc aagtatgaga atttttaaag aagatttagg taaaaaatca
     6361 tctactctag tgtatcttgc aaagctttca tttgttgcta tgattggtaa ttttgtagga
     6421 ttggctactt taataccagg atttacccct gcaaactatt atttaaatcc taatatagca
     6481 tgtttgttag tagggttgat ttttacacga ataggttttt tagaaaaagg aattttagat
     6541 aaatctcaat ctaatggaat tataatgttt ggttgtatgt tgatgttacc tggaggactt
     6601 gctaaggtaa ctccaacagc attgtttggg atgattgttc caactatagg aatacttgtt
     6661 gtaggttctg tatttataat attatttact gcaattgtag gaaaactatt gggatattct
     6721 ccaagaatgt cagctgcaat tggtgtaact tgtatgctag cttatcctgc aacacagata
     6781 atttccaacg aaggtattga tgctatggaa ggaactgaag aagaaaaaca aagggcaaca
     6841 gattatttat taccaaagat gattatagga ggatttgtta ctgtaaccat tgcatcagtg
     6901 gcatttgcta gtataatagg tccaattata tttggttgat agtaaatata cttataggag
     6961 gaataagaaa tgataggaag tatatctata aatgagatag ataaaaaaag attcaaactt
     7021 gatgatttaa gtaagaaaat atgggaaaac ccagaaaaag catttaaaga atttaaagca
     7081 tgtgaaaata cagcaaactt tctaagaagt gaaggatttg atgtggaagt aggtgtagga
     7141 ggtttagcca cggctattag agctagtttt ggttcaggta aaccagttat aggttttatg
     7201 ggagaatttg atgcattacc tggtttaaat caaaaagttt caacaaagca agaagcattt
     7261 gaattgagtg catatggtca tggatgtggg cataatttat tatgtacagc acatgtaggg
     7321 gcagtagtag gacttaaaag agagatgcta gaaaataact taagtgggac tatagtattt
     7381 tatgcatgtc caggagaaga acaattaaca ggtaaaggat ttatggctag aggtggagca
     7441 tttgaagggt tagacttagc tataaatttt catccaaata aaattagtga agctacaatt
     7501 ggtacttcaa cagctgttaa ctctgtaaaa tttcacttta agggaaagac tgcacatgca
     7561 ggctcagacc ctcaaaatgg aagaagtgca ctagatgctg tggaacttac taatgtggga
     7621 gctaattatt tgagagaaca tgttacttct gatgtaagga ttcattatac aattacagat
     7681 ggaggagtag cacccaacat agttcctgat aaagcatcag tatggtatta tacaagagct
     7741 ttaagtagag aagctgtaga aagtacatat gaaagacttg taaaggtagc aaaaggagct
     7801 gcaatgatga ctgaaactga agttgaagta gagtttttag gaggttgtta taatacttta
     7861 aataatcatg ttttagcaaa tcttgtatca gaatgtatga atgagattaa acaagagcct
     7921 tggactcgag aggaattgga ttttgcagct gaattagata gacaaagccc acaacaatat
     7981 aaggctatga taagtaaata taatttgcca gaaggaactc atctatatta tggtggagga
     8041 aatgttacaa actttaatag ttatggttct actgatattg gagatgtaat gcatatagtt
     8101 ccgacagcat acttttttac agggtgtacg aatctaggtg caccaggtca tagctggcag
     8161 tttacatctt gtgcaggaag ttctatagga gaaaaaggta tgatatatgc atcaaaaatc
     8221 atggctatgt ttggagccaa aatattaaat aatccagaga tagctaaaaa ggcaaaagaa
     8281 gagtttgata aatctatgaa tggtaaaaca tataaatgtc ctattccaga tgatattcca
     8341 actccttaaa aagacatgaa gtttaatata taaaattata atttttatat cagcatcatt
     8401 tcattactaa aagaaagtga gattttgctg actatctgat taggaggaag gaatatgaaa
     8461 aattttttta aagaagcgca gtcaatagaa ggggaaatta ttagatggag aagatattta
     8521 catgaaaatc ccgaaattgg ttgcaatcta ccgaaaacag taacctttgt taccagtact
     8581 ttagaaaaaa tgggatattc tccgaaattg acgtctaata atggaatagt agctgtttta
     8641 gacagtgaaa atggtggaaa gaccttatta ttaagggcag atatggatgc acttcctatt
     8701 atggaggaga cggatttacc ttttaaaagt aagaataaag atgcatctca tagttgtgga
     8761 cacgataatc acacagcaat gctcttagga gcagctaaaa tacttatgga taataagcac
     8821 ttacttaaag gtagagtaaa gtttgtattt gaaccagatg aagagagtac cagaggtgca
     8881 aaatcaatga ttgatgatgg tatattagaa aatcctcagg tcgatgcagc tatggcattt
     8941 cacagtatgg tgggtaaatt tcttaacaca ggtcaagtag cttattcacg tggtccagct
     9001 atggcatctg cggatatatt tgaaataaca gtagaaggaa aagcaactca tggagcaagc
     9061 cctgaatttg gagtggaccc aataaacata atgtcgcata tacaaatagc attaaacact
     9121 atactttcaa gagaaaaacc tcagaaagag cctgtagttt taactattgg tatgtttaat
     9181 gcaggaaacg taccaaatgc tataccaaat aaagcatcta tgtcaggaac tttaagaaca
     9241 tttgaccaat ttgttagaga aaaattaaaa aatagaatta ttgaaatatc tacaggaata
     9301 gctaaatcat ttggaggaaa tgctaaagtg gaatttaaaa tggggactcc cgcagttata
     9361 aatgatttgg atgtaggaga tgagattgta tcttatgtta aagaaattat aggaaatgag
     9421 aatgtaatag actttccatc tgcaatgggt tcagaagatt tttcagagat tttactaagg
     9481 gttccaggag tatttttatg gattggaatg ggaagtatta gtcagggata taattttggt
     9541 atgcataatc ctaaagcaat ttttaatgaa gagggattag tttatggttc agctttattt
     9601 gctcattgtg cagtaaaatg gttagaaaat aattttagta gataataaca taaaatatta
     9661 ttaaatatca taaaaggtat atcttaaaaa gatgcaaaga tatacctttt agaaagtcat
     9721 atataatttt acttaatatt agatgataaa atatttttat gcattttgga ttttaatatt
     9781 tattttctga tataaataat ttgtataccc tttcaggtct accttttgtt gagttttgtt
     9841 tttcatataa tatagtagcg tttccagact ttaagagact acttagaaat ctattagcag
     9901 ttctaactgt tacatttaaa catgaagata attccttagg agtaacttca tctctttgta
     9961 gaatttcagt aacagatata atcttttgaa tagtaagagt agacaattta gaacttttgg
    10021 caattgtatt tatatgtgga gttactttat ttgaaacagt aagtaactta tcacacagta
    10081 aaggtcctat tgtctcataa ttttcgttga ctaagaaact gtaatttaaa ggatttattt
    10141 tagattcctt attagcactt atggcactag acatagcttg ctttatatca ttaccaattc
    10201 catatccaac acatacttta atatttgtac tattttcaat agattctttt atataacatg
    10261 cagtaaaatt tttagttaat gatttaatcg tttcacattt agtgaaaatt ttaaaagaat
    10321 tactattttt ttcaattata aaatcggtta atttatcttt tttaatacta tttaatattt
    10381 tataaacttg gtctagagta gagtcatcat aatttgtatc tttaactgtt atatatatta
    10441 cacttggttg atttcccttc attctatgta aatgaatatc ttttattaag ttattaaaag
    10501 tattttttaa taaatctata tcagggtata tgaaatgaaa gtttactcct gcattttgta
    10561 acataggaac aatactacta aaacgagtag tagaaaaatc gattttccct tcattccata
    10621 gattaatatg tttttttgca atcttttttt caagttttgc tatgtcagat aaactcattt
    10681 tagatgcatt ttcatcaata ctatccatta agtctccaaa tgtgccattt gataaataat
    10741 atgatatatc ttttggatta tctgcccagt ctgttaagtc aaagtatgct ctagaaaaat
    10801 ctaatgtatt atatttaaag ataagcttta gaaacatatc atagtaactt tgtaagtcag
    10861 tacca
//
LOCUS       DAMJYN010000105        10765 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.110, whole genome shotgun sequence.
ACCESSION   DAMJYN010000105 DAMJYN010000000
VERSION     DAMJYN010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10765)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10765)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10765
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.110"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            296..754
                     /locus_tag="PC466_003195"
     CDS             296..754
                     /locus_tag="PC466_003195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2770552.1"
                     /translation="MEFINFVSDKVIDLKMDCKTKEDFFKEIHNKVFDLGFVKEEFGE
                     KILARENVFPTGLNLGDYGVAIPHTDAEYIKEQFISVCTFNEPVVFSSMEDQDEKVPV
                     NLAFILGLNQPHSQLSVLTELMGIMQNKELVDKLMSSTDKEEVLRTLKSL"
     gene            815..1090
                     /locus_tag="PC466_003196"
     CDS             815..1090
                     /locus_tag="PC466_003196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2770553.1"
                     /translation="MKKILVACGAGIATSTVVCDKVERLVKENNIQAEVIQCKIAECA
                     TKQEGADLIVSTTILPTTYNIPAIKATAYITGVNTAALDKKILDALK"
     gene            1149..2423
                     /locus_tag="PC466_003197"
     CDS             1149..2423
                     /locus_tag="PC466_003197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012951111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HDF2770554.1"
                     /translation="MDKLLAVVQYILNMGPTVILPITIVVLGMIFRIKFTKALKSGLT
                     IGIGFVGINLVVNLLTSTLGPAAQGMVERFGLNLTVIDVGWPTTASATWASPVAPILI
                     PVCLLVNLLLLYFNKTKILNVDIWNYWHFIVAGAVGYIVTGSYVWAIFCAILMELLVL
                     FIAEKTAKNVQEFYDLEGIALPTGSTASFAPLGYLVGKFVEKIPGINKIQADPDSIQK
                     RFGIFGEPMMMGIILGIILGALAGYDVAGIFNVGISMGAVMLLMPRMVRILMEGLIPI
                     SESIRDFLQAKYGDRELYIGLDAAVATGHPAVISTALILVPITLFLAVILPGNKVLPF
                     GDLATIPFYMAFIVCFRKGNIVQSVITGTIVIAISLYMATNFADVHTQLLQQANMMPE
                     GTTMVTSIDTGGNLLKWGILKLSQLVSSFGIF"
     gene            2553..3605
                     /locus_tag="PC466_003198"
     CDS             2553..3605
                     /locus_tag="PC466_003198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HDF2770555.1"
                     /translation="MKAAVLHGTNDMRFEDIEIKPCESDEVKIKVMAAGICGSDPPRV
                     LKHWKYPVPAIPGHEFSGVIAEVGKDVKNVKVGDRVVAIPFIPCNECEYCKRGLFSLC
                     DDHGMLGAKSFGAFAEYVNIKATNVLPIGDMDFEDAAMIEPLAVAMHGVLNIGVQVGD
                     AVAVMGSGTMGQLVIQGLKIAGAGTIIAVDISDNKLRESKELGADIIINAKDIDPVEK
                     IKELTGGKGVDIALECAGSKITQEQCLLITKKKSKIGFLGIAYSDITLSEEAFENIFR
                     KELELKGFWNSYSAPFPGQEWTKGINLVNEGKIKLKEMVSHRFSLEDTYKAFEMIRDR
                     KEEFNKILILPQGVEK"
     gene            3605..4636
                     /locus_tag="PC466_003199"
     CDS             3605..4636
                     /locus_tag="PC466_003199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012986518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding dehydrogenase"
                     /protein_id="HDF2770556.1"
                     /translation="MKAVVKTKPGYDNVEVLEVEEPKATGDKVKIKVEYSGICGSDIH
                     SFKGEYANIKAPVTLGHEFSGIVVEVGEDVKDIKVGDRVTSETTFATCEKCIYCETKD
                     YNLCPTRKGIGTQVNGSFAEYVLSREESIHVLPENVSLLSAALTEPLACCVHAALEKT
                     TIESSDTVLIIGPGPIGLLLAQVVKSQGATVIMSGVTKDKERLEIAKNLGVDRTVNVM
                     EESLADVVNEMTDGNGVNKGFDCSGFMPAVNEALRLLRKKGTFVQVGIFAKKLNEMDQ
                     EAIIQRELQYIGSRSQKPSSWITALDLMASGKVNTEALVTRTVGLDEFKEGITALMNG
                     EEIKVAVKS"
     gene            4728..5540
                     /locus_tag="PC466_003200"
     CDS             4728..5540
                     /locus_tag="PC466_003200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HDF2770557.1"
                     /translation="MSTLRDHSNNIRKNIIKMVAEAKSGHPGGSLSIADMLTVLYFDK
                     MNVCAENPKMADRDRFVLSKGHAAPALYATLAEKGFFPEEELITLRKFGSKLQGHPDM
                     KKVAGIDMSTGSLGQGLSAANGMALAGKLDNKDYTVYTILGDGEIQEGQIWEAAMTAS
                     HYKLDNLIAFVDLNGLQIDGSNEEVMNVNPVDDKFKSFGWNVIVINGHSFEEIGNAVD
                     EAKKVTGKPTVIIAKTVKGKGVSFMENNAAWHGTAPNAEQAEQALKDLEGGL"
     gene            5543..6463
                     /locus_tag="PC466_003201"
     CDS             5543..6463
                     /locus_tag="PC466_003201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HDF2770558.1"
                     /translation="MGIATREAYGQVLKELAENKDIVVLDADLGKATKSISFKEVAPD
                     RFFDMGIAEGDMIGTAAGLATCGKIPFASTFAIFAAGRGYEQIRNSVAYPNLNVKIAA
                     THAGVTVGEDGGSHQAIEDISLMRGIPNMVVLNPADALEARQAILASIDYNGPVYIRL
                     GRAATPDVNSENYKFEIGKGTVLREGSDITVIATGIMVAKALEAAEELAKEGINVEVV
                     NISTIKPLDEALIKETAKKTGKVVTAEEHSIIGGLGSAVCEALAETKDVVVRRIGVKD
                     VFGQSGTPADLLKHYGLTTEDIVKNIKELL"
     gene            6638..7084
                     /gene="rpiB"
                     /locus_tag="PC466_003202"
     CDS             6638..7084
                     /gene="rpiB"
                     /locus_tag="PC466_003202"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose 5-phosphate isomerase B"
                     /protein_id="HDF2770559.1"
                     /translation="MKISIGCDHGGYELKEYIKENLINKGIEVEDVGTNSKESVDFPI
                     YAKKVSQNVQSKKSDLGILCCGTGIGMSIAANKFKGIRAAVVSDCFSAKATREHNNTN
                     VLCLGERVIGKGLAMRIVEEWLNSSYNGERHARRLQMIDDIEKENL"
     gene            7123..7788
                     /locus_tag="PC466_003203"
     CDS             7123..7788
                     /locus_tag="PC466_003203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HDF2770560.1"
                     /translation="MSIICASIMCADQMKLKEELEALEEAGVKLLHCDVMDGIFVKNL
                     AMGPELLKSISENTTIPLDIHLATETPDKYIDMMSYIKPKYISFHVESSTNVKADIQK
                     LRNYGIGPVLAISPQTSVDKIEEYISLVEGILVMTVNPGFAGQKFNLSVLDKLDKLTE
                     ILKDYDNPPFIEVDGNINKDTIKLMNGKKVDIYVVGTSALFNDKPPISYKDKIEELKE
                     SIK"
     gene            7898..9400
                     /locus_tag="PC466_003204"
     CDS             7898..9400
                     /locus_tag="PC466_003204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HDF2770561.1"
                     /translation="MGDLYKLQNGTDIRGIAYENDSKEVNLTVEEVKKIAKAFHIWLK
                     EKTKKDKVTVAIGTDSRITGSQFRSTVIETLTNDDCNVIDCEIATTPAMFMTTIMDGY
                     NSDGAIMITASHLPYYYNGLKFFTESGGLEKTNIKEMLDIAVKNDSVDYEEVNKKGEV
                     IVKNLIEDYSNLLIDKIRKGVNSSKNYEKPFSGLKILVDAGNGAGGFFAEKVLHILGA
                     DTTGSQFLNPDGMFPNHIPNPENKEAMESICKAVLDNNSNLGIIFDTDVDRAAIVGKN
                     GKPINKNALIAVISSIVLEEHPKTAIVTDSITSEGLAKFINELQGRHHRFKRGYKNVI
                     NEAIRLNSEGEECHLAIETSGHAALKENYFLDDGAYLIAKILIKVAKLSLEGKTIEEL
                     IENLEEAQEEKEVRIGINKEDFRPYAEDILKDLDSHVKSIDGWSVAPNNFEGIRVNCD
                     ESNGDGWFLLRISLHEPLLALNIESNKIGGAEQIYSKLKLFLEKYDLKGL"
     gene            complement(9712..>10765)
                     /locus_tag="PC466_003205"
     CDS             complement(9712..>10765)
                     /locus_tag="PC466_003205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDF2770562.1"
                     /translation="SNLLSMYNKKTINKKLAIVFLISIVVQAIIQYLVLIFFMYIYYS
                     EAIAIVILFTLVNTVFHFYIYNFLSVKFNYINNISKNIKNIENGNLKYKLEVIGDDEI
                     STLAKSINNITGGLETAVDANIKNERMKAELITNVSHDLKTPLTSILSYVDMLKNNDF
                     DRETINDYINILDKKSQRLKLLIDDIFEASKLSSGDVEFNITKTDIRELLIQSIVEFE
                     DKIQNSSLDFIIETPEYAVFTMIDGKKTWRVFENLICNILKYSMPNTRVYIDMFIKEE
                     NIILTFKNISNDKLNLKPEELIERFRRGDISRKTDGSGLGLSIAQNIIELENAHMEII
                     IDADLFKVMLTFRRVN"
BASE COUNT         4299 a         1225 c         1973 g         3268 t
ORIGIN      
        1 gttgttaaac ataaaaaacc atttgtaaaa aacaaaaaaa tcatttctct aacaaaaaaa
       61 accacaaaaa atataaaaaa gtatggctag ttaagtgatt aacaagtaaa aattaaaata
      121 aaaatcaaaa aaaatttatc aatgaaagtc agctaaaatc ctggaagaga gcattatttt
      181 cgggaaaaca ttttcttttg tttcacaaaa aaagccactt tttggcacgc aacatgcttt
      241 atataaagtc aagaaaaact aaggtataag acaaaggcaa ttaggaggtg taaatatgga
      301 gtttataaat tttgtaagtg ataaagttat agaccttaaa atggattgta aaacgaaaga
      361 agatttcttt aaagaaatac ataataaagt ttttgattta ggctttgtaa aagaagaatt
      421 tggagaaaaa atattagcaa gagaaaatgt atttccaaca ggtttaaatt taggtgatta
      481 tggagtagca ataccacata cagatgcaga atatattaaa gagcaattta tatcagtctg
      541 tacttttaat gaaccagtag tatttagttc tatggaagac caagatgaaa aagtacctgt
      601 aaatttggct ttcatattag gacttaatca accacacagt caattatctg tattaacaga
      661 attaatggga attatgcaaa ataaagagtt agttgataag ttgatgagtt ctactgataa
      721 agaagaagtt ttaaggacac taaagtcttt ataaaaataa aaaagtacta aaaataaaaa
      781 atataaaaat aaaaattatt aggaggaaat aaaaatgaaa aaaatattag tagcatgtgg
      841 agcaggaata gcaacatcaa cagtagtttg tgacaaggta gagagattag ttaaggaaaa
      901 taatatacaa gcagaagtta tacaatgcaa aatagctgaa tgtgcaacaa agcaagaagg
      961 agcagattta atagtatcaa caactatact accaacaact tataatatac cagcaataaa
     1021 agcaacagca tatataactg gagtaaatac agcagcatta gataaaaaaa tattagatgc
     1081 tttaaaataa tcctatcata gatacattga aataatattt tataaaacag aaaaaggagg
     1141 atttataaat ggataaatta ttagcagtag tacaatacat tttaaatatg ggaccgacag
     1201 taatactacc aataacaatt gtagtactag gaatgatatt tagaattaag tttacaaaag
     1261 ctttaaagtc aggtcttaca attggtatag gatttgtggg tataaactta gttgtaaacc
     1321 tattaacatc aacactaggg ccagcggctc aaggaatggt tgaaagattc ggacttaatt
     1381 taacagtaat agatgttggt tggccaacaa cagcatcagc aacatgggct tcaccagttg
     1441 caccaatatt aataccagtt tgtttattag taaacttact attattatac ttcaataaaa
     1501 caaagatatt aaacgttgat atatggaatt attggcactt tatagtagca ggtgcagttg
     1561 gatatatagt aacaggaagt tatgtttggg ctatattctg tgcaatacta atggagttat
     1621 tagtactgtt tattgcagaa aagacagcaa aaaatgttca ggagttttat gatttagaag
     1681 gtatagcatt accaactggt tcaacagctt catttgctcc acttggatat ttagtaggta
     1741 aatttgttga aaaaatacca ggaataaata aaatacaagc agacccagac tctatacaaa
     1801 aaagatttgg tatatttgga gaaccaatga tgatggggat tatactaggt ataatacttg
     1861 gagcacttgc gggatatgat gtagcaggaa tattcaatgt aggtatatca atgggtgcag
     1921 taatgttact tatgcctaga atggttagaa tattaatgga aggtttaatt ccaatttcag
     1981 aatcaataag agatttctta caagcaaaat atggagacag agaactttat ataggtctgg
     2041 atgcagcagt agcaacggga catccagcag ttatatcaac agctcttata cttgttccta
     2101 taacgttgtt cttagcagtt atactaccag gaaacaaagt tttaccattt ggagacttag
     2161 cgacaatacc attttatatg gcatttatag tgtgctttag aaaaggtaat atagttcaat
     2221 cagttataac aggaacaata gtaatagcta tatcacttta tatggctaca aactttgcag
     2281 atgttcatac acaattatta caacaagcaa atatgatgcc agaaggaaca acaatggtta
     2341 caagtataga tacaggtgga aacttgctaa aatggggaat attgaaatta tctcaattag
     2401 tttcttcatt tggaatattc taatatgtag ttaatagaga ttactctttt ttagtaaagt
     2461 atgcgaaaat ttaacattta gcagctacta aaaaagagta atatttttta taaattttta
     2521 aaaatacaaa atacaagagg aggagattta tcgtgaaagc agcagtatta catggcacaa
     2581 atgatatgag atttgaagat atagaaataa aaccatgtga aagtgatgaa gtaaaaataa
     2641 aagttatggc agcaggaata tgtgggtcag atcctccaag agtattaaaa cattggaaat
     2701 atccagttcc agctatacca ggacatgagt tttctggagt aattgctgaa gttggtaagg
     2761 atgtaaaaaa tgtaaaagtt ggagatagag tagttgcaat tccttttata ccttgtaatg
     2821 aatgtgaata ttgtaaaaga ggattatttt cattgtgtga tgaccatgga atgttaggag
     2881 ctaaaagttt tggagctttt gcagagtatg taaatataaa agctacaaat gtacttccaa
     2941 taggagatat ggactttgaa gatgctgcaa tgatagagcc actagcagtt gctatgcatg
     3001 gagtacttaa tataggtgtt caagttggag acgctgtagc cgtaatgggt agtggaacaa
     3061 tggggcagtt ggtaatacaa ggacttaaaa tagcaggagc aggaacaatt atagcagttg
     3121 atatatctga taataaatta agagaatcaa aggaattagg ggctgatata ataatcaatg
     3181 ctaaagatat tgacccagta gaaaaaataa aagaacttac tggtggaaaa ggcgttgaca
     3241 tagctcttga atgtgcaggt tcaaaaataa ctcaagaaca atgtttactt ataactaaaa
     3301 agaaaagtaa gataggattt ttagggatag catattcaga tataacttta tcagaagaag
     3361 catttgaaaa tatatttaga aaagaactag aattaaaagg tttttggaac tcttattctg
     3421 caccatttcc aggacaagaa tggactaagg gaatcaatct agttaatgaa ggaaagataa
     3481 aattaaaaga aatggtatct catagattct cacttgaaga tacttacaaa gcatttgaaa
     3541 tgataagaga tagaaaagaa gaatttaaca aaatattaat tttaccacaa ggggttgaaa
     3601 aataatgaaa gcagtagtta aaactaaacc aggctatgat aatgtagaag ttttagaagt
     3661 agaagaacca aaagctacag gagacaaggt taaaataaaa gtagaatata gtggtatatg
     3721 tggttcagat atacattcat ttaaaggtga atatgcaaat ataaaagccc cagtaacatt
     3781 aggtcatgaa ttttctggaa ttgttgtaga agtaggagaa gatgttaaag atataaaagt
     3841 aggagataga gttacatcag aaactacttt tgcaacttgt gagaaatgta tatattgtga
     3901 aactaaagat tataacttat gcccaactag aaaaggtatt ggtactcaag taaatggaag
     3961 ttttgctgag tatgtactat caagagaaga aagcatacat gtacttcctg aaaatgtatc
     4021 tttattatca gcagccctta cagagccact agcttgttgt gttcatgcag ctcttgaaaa
     4081 gactactata gaaagttctg atacagtttt aataatagga ccagggccaa ttggtttatt
     4141 attagctcaa gttgttaaat ctcaaggtgc tacagttata atgtctggtg ttacaaaaga
     4201 taaggaaaga ttagaaatag ctaaaaatct tggagtagat agaactgtaa atgtaatgga
     4261 agaaagtttg gcagatgtag tgaatgaaat gactgatgga aatggagtaa acaaaggatt
     4321 tgattgttct gggtttatgc cagcagttaa cgaagcctta agactgctta gaaaaaaagg
     4381 tactttcgta caagttggaa tctttgctaa aaaattaaat gaaatggacc aagaagcaat
     4441 aatccaaaga gagttacaat atataggaag tagatctcaa aagccaagtt cttggattac
     4501 agcattagat ttaatggcaa gtgggaaagt aaatacagaa gctttagtta ctagaactgt
     4561 tggtttagac gaatttaaag aaggtattac agctttaatg aacggggaag aaataaaagt
     4621 agcagtaaaa tcttaaaaaa acatttgtat tattttaaaa aaaattgtaa aatctactgt
     4681 aggataaaaa aatgtaaggt cttaaaaaat aacaggagga agaaagtatg agcactctta
     4741 gagatcattc taataatatt agaaaaaaca taataaaaat ggttgcagaa gctaaaagcg
     4801 gacatccagg tggttcatta tcaatagctg atatgttgac agtattatat tttgataaga
     4861 tgaacgtatg tgcagaaaat ccaaaaatgg ctgatagaga tagatttgtt ctatcaaaag
     4921 gtcatgcagc accagcttta tatgctacat tagcagaaaa aggatttttc ccagaagaag
     4981 aattaataac actaagaaaa tttggttcta agttacaagg tcacccagac atgaaaaaag
     5041 tagcaggaat cgatatgtct actggttctc ttggtcaagg gctatctgca gcaaatggta
     5101 tggcacttgc aggaaaatta gataacaaag actatacagt atatactata ttaggtgatg
     5161 gagaaatcca agaaggtcaa atatgggaag ctgcaatgac agcatcacat tacaaattag
     5221 ataatttaat tgcatttgtt gacttaaatg gattacaaat agatggttct aatgaagaag
     5281 taatgaatgt aaatccagta gatgacaaat tcaaatcttt tggatggaat gtaatagtaa
     5341 taaatggaca ttcttttgaa gaaataggaa atgcagttga tgaagctaaa aaagttacag
     5401 gaaaaccaac tgtaataata gctaaaacag taaaaggtaa aggtgtttca tttatggaaa
     5461 ataatgctgc atggcatgga acagctccaa atgcagaaca agcagagcaa gcattgaaag
     5521 atttagaagg aggtctatag gaatgggaat agcaactaga gaagcttacg gacaagtgtt
     5581 aaaagaactt gcagaaaata aagatatagt agtattagat gcagatttag gaaaagctac
     5641 aaaaagtata tcatttaaag aagttgcccc agatagattt tttgacatgg ggatagcaga
     5701 aggtgacatg attggtacag cagcaggtct tgctacttgt ggaaaaatac cttttgcgag
     5761 tacttttgca atatttgcag caggaagagg ctatgagcaa ataagaaact ctgtagcata
     5821 tccaaattta aatgtaaaaa tagcagctac tcatgcaggt gtaacagtag gtgaagatgg
     5881 tggtagccat caagctatag aggatatatc tctaatgaga ggtataccaa atatggttgt
     5941 attaaatcca gcagatgctt tagaagcaag acaagctatt cttgcatcta ttgattataa
     6001 tggacctgtt tatataagat taggtagagc tgcaactcct gatgtaaaca gtgaaaatta
     6061 taaatttgaa ataggaaaag gaactgtttt aagagaaggt tctgacataa cagtaatagc
     6121 tacaggaata atggtagcaa aagccttaga agcagcagaa gaacttgcta aagaaggtat
     6181 aaatgtagaa gttgttaata tatctacaat aaaaccatta gatgaagcat taataaaaga
     6241 aactgctaag aaaactggaa aagtagttac agcagaggag cacagtataa taggtggttt
     6301 aggttcagct gtatgtgaag ctttagcaga aactaaagat gtagtagtta gaagaattgg
     6361 tgttaaagat gtatttggtc aatcaggtac accagctgat ttattaaaac actatggttt
     6421 aactacagaa gatatagtaa aaaatataaa agagttgtta tagatataaa tatatctaaa
     6481 taacaaattg atttgacata agtcaattaa agctgtctta aaaatagaaa gaaatttcta
     6541 caatgggaca gctttatttt tacaatactt tatttttatg ataattataa aatagtctga
     6601 aagtaatcaa aaaaattata aaaagaggtg ctatttaatg aaaatatcta ttggatgtga
     6661 ccatggtggt tatgaattaa aggaatatat aaaggaaaat ttaataaata aaggtataga
     6721 agttgaagat gtgggtacaa attcaaaaga aagtgtagat tttccaatat atgcaaaaaa
     6781 ggtaagtcaa aatgttcaaa gtaaaaaatc tgatttaggc atactttgtt gtggaacagg
     6841 aataggcatg tctattgcag caaataagtt taaaggaatc agagcagctg ttgtttctga
     6901 ctgtttttca gctaaggcaa ctagagaaca caataataca aatgtacttt gtttaggaga
     6961 aagagttatt gggaaaggat tagcaatgag aattgttgaa gaatggttaa attcaagtta
     7021 taatggagaa agacatgcaa gaagattaca aatgattgat gatatagaaa aagaaaattt
     7081 ataaatatat ataatatata atttataaca agggggagcg ttatgtctat tatttgtgct
     7141 tcaataatgt gtgcagacca aatgaagtta aaagaggaat tagaagctct tgaagaagca
     7201 ggtgtaaaat tacttcattg tgatgttatg gatggaatat ttgttaaaaa cttggctatg
     7261 ggaccagagt tattaaaatc aataagtgaa aatacaacaa tacctttaga catacactta
     7321 gccacagaaa ctccagataa atatattgat atgatgtctt atataaagcc aaaatatatt
     7381 tcttttcatg tagaatcaag tacaaatgta aaagctgata tacaaaagtt aagaaattat
     7441 ggtatagggc cagtgttagc aataagccct caaacaagtg tggataaaat agaagaatat
     7501 ataagtttag ttgagggtat cttagtaatg acagtaaatc cagggtttgc aggtcaaaag
     7561 tttaatcttt ctgtattgga taagttggat aaacttacag agatactaaa agattatgat
     7621 aatcctccat ttatagaggt tgatggaaat ataaataagg atactattaa acttatgaat
     7681 ggtaaaaaag tagatatata tgttgttggt acttcagctt tatttaatga taagcctcca
     7741 atttcatata aagataaaat agaagaacta aaagaaagta taaagtaacc atgtaataaa
     7801 attataatat gtttctgttt aatagtaaaa atttaggtgg aaacaagaaa ttttataata
     7861 tttaataaaa attttggttg agtaaggaga attttttatg ggagacctat ataaactaca
     7921 aaatggtact gatattagag gaatagcgta tgaaaatgat tctaaagaag ttaacctaac
     7981 tgtagaagaa gtaaaaaaaa tagctaaagc gtttcatatt tggctaaaag aaaagactaa
     8041 gaaagataaa gtaactgttg ccataggaac tgattctagg ataacaggaa gccaatttag
     8101 aagtactgtt attgaaactt taactaatga tgattgtaat gtaattgatt gtgagattgc
     8161 tacaactcca gctatgttta tgacaactat tatggatgga tacaattctg atggggcgat
     8221 tatgattaca gcaagtcact taccttatta ctataatggt ttaaagtttt tcacagaaag
     8281 tggaggttta gaaaaaacta atataaaaga gatgttggat atagctgtta aaaatgatag
     8341 tgtagactat gaggaagtaa ataaaaaagg tgaagttata gtaaaaaatt taatagaaga
     8401 ttattctaat ttattgatag ataaaattag aaaaggtgta aattcaagta aaaattatga
     8461 aaagcctttt tctgggctta agatattggt tgatgcagga aatggagctg gtggattctt
     8521 tgctgaaaaa gttttacaca tactgggagc agatacgaca ggcagtcagt ttttgaaccc
     8581 agatggtatg ttcccaaatc atatacctaa tcccgaaaac aaagaagcaa tggaaagcat
     8641 atgtaaagct gtgttggata ataatagcaa cctaggaata atctttgata cagatgtaga
     8701 cagagctgct attgtaggta aaaatggcaa accaataaat aaaaatgctc ttatagctgt
     8761 tatatcatca atagtattag aagaacatcc aaaaacagct atagtaacag attcgattac
     8821 ttctgaagga cttgctaaat ttataaatga attacaagga agacatcata gatttaaaag
     8881 aggatataaa aatgtaataa atgaagctat aagattgaat agtgaaggtg aagagtgcca
     8941 tttagctata gaaacgtctg gacatgctgc tttaaaagaa aattatttct tagatgatgg
     9001 ggcatattta atagctaaaa ttttaataaa agtagcaaag ctatccttgg aaggaaagac
     9061 tatagaagaa ttgatagaaa accttgaaga agctcaagaa gagaaagaag ttagaatagg
     9121 cattaacaaa gaagatttta gaccatatgc agaggatata ttaaaagatt tagattctca
     9181 tgttaagagt attgatggat ggtctgtagc accaaataat tttgaaggaa taagagttaa
     9241 ttgtgatgaa tcaaatggag atggatggtt tttacttaga atatcactac atgaaccatt
     9301 actagcttta aatattgaat caaataaaat tggtggagca gaacaaattt attctaagtt
     9361 aaaacttttc ttagaaaaat atgatttaaa aggtctttag ggtaaataga aagaatatat
     9421 ttatattaaa gaacaaatgt aaatttgtac ctaagattac aaatattaca aaattgtaat
     9481 cttaggtaac agagatgtaa ctgattatgg aaacactatg tgatattata gatacagaga
     9541 gatgaaatat gtgatgaatt atagagaaat ataatttaaa atgtattaat atcacaccaa
     9601 aaaggtataa tcaaaaaata tgtaaatata aaccccaaca tttagaaaaa gacctctaag
     9661 gaggtttttt tcttgtttaa ataacttaaa atatattttt atattaatat atcaattaac
     9721 tcttctaaaa gtaagcatta ccttaaataa atcagcatct ataattattt ccatgtgtgc
     9781 attttctaat tcaattatat tttgagcaat tgataaacca agaccagagc catctgtttt
     9841 tctagatata tcaccccttc taaatctttc tattaactct tctggcttta gatttagttt
     9901 atcatttgaa atatttttaa acgttaatat tatattttct tcctttataa acatatctat
     9961 atagacccta gtgttaggca tagagtattt tagtatattg caaattagat tctcaaaaac
    10021 tctccaagtt tttttaccat ctatcatggt aaaaacagca tattcaggtg tttctattat
    10081 aaaatctaaa ctgctatttt gaattttgtc ttcaaactct acaatacttt gaattaaaag
    10141 ttctcttata tcggtttttg ttatattaaa ttctacatct ccactactta gcttagatgc
    10201 ttcaaatatg tcatctatta ataattttaa tctttgtgat tttttatcta aaatatttat
    10261 atagtcattt atagtctctc tgtcaaagtc attatttttt aacatatcaa catagcttaa
    10321 tatagatgta agtggagttt ttaagtcatg agatacgttt gtgataagct ctgccttcat
    10381 cctttcattt tttatattag catctacagc agtttcaaga ccacctgtta tattatttat
    10441 acttttggct aaagtagata tttcatcatc tcctataact tctaatttat actttaaatt
    10501 gccattttct atatttttta tattttttga tatgttattt atgtaattaa acttaacaga
    10561 taaaaagttg tatatataaa aatgaaaaac tgtgtttaca agtgtaaata aaattactat
    10621 agctattgcc tcagaataat atatatacat aaagaatatc aaaacaagat attggataat
    10681 agcttgtaca actatagata ttaaaaatac tatagctaat tttttattta tagttttttt
    10741 attatacata ctaagtaagt ttgaa
//
LOCUS       DAMJYN010000106        10673 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.111, whole genome shotgun sequence.
ACCESSION   DAMJYN010000106 DAMJYN010000000
VERSION     DAMJYN010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10673)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10673)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10673
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.111"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(3..647)
                     /locus_tag="PC466_003206"
     CDS             complement(3..647)
                     /locus_tag="PC466_003206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2770563.1"
                     /translation="MEQHSKVGNFGDLLKVLLDEKELSMGELSKKSGIDKSTISRIAN
                     NKQRPNINHLEKMAIHLNINLEELLKASGYEFRNSNNQIFNADSDFSNFDDILGFANL
                     INDKNFNGNIEKELSKCKLYVQTDEGKKLLFDNFNKKIDSIEKQGQFTDRLRQMYADF
                     CTDGLTIKKYLLIGSMLLYFVISTDVIPDFVFPIGFMDDLVALNIVTKLLKNDK"
     gene            832..1455
                     /gene="ytaF"
                     /locus_tag="PC466_003207"
     CDS             832..1455
                     /gene="ytaF"
                     /locus_tag="PC466_003207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation membrane protein YtaF"
                     /protein_id="HDF2770564.1"
                     /translation="MIESILLVTSLCIDAFVTSFGYGVNKVKVPLYSNIIISVVCSAI
                     LAISLFAGTIVRDFLPQNITMLICFFILFLLGSARLIESFFKSYFKKKSIHSKNYNFN
                     MLDLELNFNVSIEPDVLDTSKSKVLKSAEAFTLALALSLDGLAIGFGSGLVGVNYIQV
                     ILFSLISNIIAVLLGCLLGNMFVKNVNLNLSWLSGLILLVIGFMKIC"
     gene            complement(1518..3428)
                     /locus_tag="PC466_003208"
     CDS             complement(1518..3428)
                     /locus_tag="PC466_003208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HDF2770565.1"
                     /translation="MNSNTFERLQLNEVKDLIKIHCVSSLGKNLIDKLTPSGNIGVVR
                     RKLAENKEARKIIENSNHIPLEGLFNAGSTIDKIEKGMIIEPVELVNIEDFLRGCRKM
                     KAFMLEKEFYSPTLSSYALNITECKSIEDEINYCIKSNKVDSNASKELKKIRRNIEIT
                     EGKIKDRLNKFITSTVNKKYIQEFIISKRNDRYVIPIKSSYKNEVNGTILDTSSKGNT
                     VFIEPISVSNLSTELTMLKADETIEEYKILSYLTELIFEKISQIKLNIEILSEYDMVF
                     AKAKYSQKIKGITPKINNNGYIKIIKGKHPLLTGDAVPLDFEIGKNYRSLIITGPNAG
                     GKTVTLKTVGLLTLMVQCGFDISAKEGSEFSVFEKVFVDIGDNQSIENALSTFSSHIK
                     NIAEIMSLSNNSTLVLFDEIGSGTEPNEGAGLAISLLEEFYKMGCITIASTHYGEIKK
                     FATLHPEFENAGMMFDKETLEPLYKLTIGKSEDSNALFISKKMGIKNRVLDRAKEYVI
                     DRNYNLDLVKRSKLQSNIEDKNSSEVILSYTDYNVGDKVKLLDEDDFGIVYKPMDKFN
                     NVEVLFNDNFISVNIKRLQLSIKASELYPEGYDLDVLFTSFKERKLEKDIQRGSKKAL
                     KKIQKEIRENRK"
     gene            complement(3965..5032)
                     /locus_tag="PC466_003209"
     CDS             complement(3965..5032)
                     /locus_tag="PC466_003209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA ligase RtcB family protein"
                     /protein_id="HDF2770566.1"
                     /translation="MSNIKIIASNKCWIEDIARKQLEDISKLNGILRVVGLPDLHTGK
                     IPVGLAVETKNIIYPHIIGNDIGCGMTLFKTGVLKKKFKKDKWIKSLSKIKDLSDIEI
                     KNTYKEECPILNLGTIGSGNHFVEIQCISEIYNKEQFEQLKFSSDDIMMLVHCGSRNY
                     GEDILKKFYDKDGLEVESEKAIDYIKKHDNALMWAERNREAISKKIMQSIGTSEDVET
                     IFSINHNFIEKREDKFIHRKGAVSSERGAVIIPGSRGSLSYIVMPTENTEISLYSLSH
                     GAGRKWSRSVCKSRLKSKYSKDTIKQTKFKSQIICNDVNLLFQEAPEAYKNIEQIIES
                     LIEYELIQVVATMKPLITYKG"
     gene            complement(5278..6273)
                     /locus_tag="PC466_003210"
     CDS             complement(5278..6273)
                     /locus_tag="PC466_003210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase"
                     /protein_id="HDF2770567.1"
                     /translation="MYEEVTWLNFIGNRYEVVNSDDVLEINKIYKARDVFYRRNVLIK
                     VIKHNNYICEDFVSNLIDESTALDEINSPYILKIIDVGIHCTEETTLYYVVSEDFNGI
                     GLDELILGNYLHLEAIVNIMIQVLKALEMIHRNHSYHGSLKSSSIIVDTEYNIKICDF
                     GITKANNGVNTRSYGNRRYLCPHQLCINYTDKESDFFATGLILFESIFKKLPFGESNS
                     EEKMLQSIDKGLDWNSIKAINGNTELINVIKRLLGRNNKYTRANDIIIDLSKVMYEKA
                     YIEVEDEKEEEQKQDKVIQVKKEYKSKMRKKLHKKLVVAGLAIVMISMIIISSII"
     gene            complement(6532..7791)
                     /locus_tag="PC466_003211"
     CDS             complement(6532..7791)
                     /locus_tag="PC466_003211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanW family protein"
                     /protein_id="HDF2770568.1"
                     /translation="MGRRTTRVSRLGKEKKRSVLIVLAALVLIMGGFTYFFNSKFLYN
                     GKIAKNVYIEGVNVSDMTKAEALKAITDKYTPEDLNLTYDGKKYTISPKDIDLKYDTE
                     DVVKDAYESTKKGSYFQNLKKYIDIRVNKANMKIKAEYDEAKLSSKVSSIADSINVKM
                     KNASISVGSGGLSYTDSVVGREFDLAANKESIYNMIKNKEHKTLELKVNLQKPDITTE
                     QVKTVNSVIGQYSTTYSQAVEGRSYNVGLSARKTSDVLLMPGEEFSYNKLTGPSNKAN
                     GYKDAPVIVYGKLEQSAGGGVCQTSSTVYNAALLSGMEITQVTNHSSASTYVPKGRDA
                     TVSDGGLNLKFKNPYKHPVYIKNYAGGGSVSSVIYGNSGDKPNISIEVKQTGQNKYST
                     YRIFKDSSGKVIKKEHISNSSYKELKK"
     gene            complement(8030..8659)
                     /locus_tag="PC466_003212"
     CDS             complement(8030..8659)
                     /locus_tag="PC466_003212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HDF2770569.1"
                     /translation="MKIVTYNIHKGMDSNNRLTLTKMGLYLKQLDCDVICLQEVLYPQ
                     FLALKAVLNMDGVFATNVKKVNMIYGICTFTTSKMLNSNHFFLTSKKEQRGALCITID
                     AYGRIINVINTHLGLDRQERAKQLDEIIDYRNRLVGIVILCGDFNEKNVFLSMFNDMA
                     ISLNKSYLPTFEKSNSRIDYIFVNKNTELKGYTVEKIYLSDHYPVIGYI"
     gene            complement(8852..9013)
                     /locus_tag="PC466_003213"
     CDS             complement(8852..9013)
                     /locus_tag="PC466_003213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770570.1"
                     /translation="MIIPSRRIQDITLTNLKNGEVTLIELDEIYKKMGFLFVVSEGKL
                     KKIKKENHH"
     gene            complement(9356..10516)
                     /locus_tag="PC466_003214"
     CDS             complement(9356..10516)
                     /locus_tag="PC466_003214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF819 family protein"
                     /protein_id="HDF2770571.1"
                     /translation="MIETGFVYCSFLVVFVGVIFFMVDKLKWKVFDVINPMLLIYLGS
                     AILGSFGLFAQNEDVGTYQNIITVNFLPLMLVFLLIQCDLRKILKMGPKMLLSFFCAT
                     FTFMLGFVIAFIIFKNSMGADSWKILGAASGSWIGGSSNMIAAANALGVAEEGLSYAI
                     LMGSIGYTVWMSVCLMSVKFGPKFNKWTKCDTSFIDEVTSKLEKENKDNTAPTFVELM
                     ILLSVGFGVASFAQIVSKILPTSGILNETMWVVLVASTVSILLGMTKISKLKGSTLVG
                     NVFMYLLLAATGSKANFFGLSEAPVYIMFGLVVVLVHAISFIGLAKLFKLDLFTCEVG
                     SIANIGGVTTAPMIAGVHNPVLIPVGVLMGLLGNIIGTYCALVVTQILHMLA"
BASE COUNT         3498 a         1749 c         1054 g         4372 t
ORIGIN      
        1 acttacttat catttttaag taattttgta actatattta atgctactaa atcatccata
       61 aatcctattg ggaacacgaa gtctggaatc acatctgttg atataacaaa gtaaagtagc
      121 atacttccaa tcaataaata tttctttatt gtaagtccat ctgtacaaaa atcagcatac
      181 atttgtctta atctatctgt aaattgacct tgtttttcaa tagaatctat ttttttatta
      241 aaattatcaa aaagtaattt tttaccttca tctgtttgga catataactt acacttactt
      301 aactcttttt caatatttcc attaaagttc ttatcattga ttaaatttgc aaatccaaga
      361 atatcatcaa agttactaaa atcactatct gcattaaata tttgattatt gctgtttcta
      421 aattcatatc ctgaagcttt caacagttct tctaggttaa tatttaaatg tattgccatc
      481 ttttctaaat gatttatatt tggcctttgt ttattattag ctatacgaga tatagtagat
      541 ttatcaattc cacttttttt acttagttct cccattgata attctttttc atctaataaa
      601 actttcaaca aatcaccgaa attcccaacc ttactatgtt gttccattat tttcacctgc
      661 tttattatga ttggttttat attatatgat atgattcttt tgttatttag gtgttgtatg
      721 atgttgaaat tttatcaaca atttattgga ttatctgtaa caatttatcc atttttacaa
      781 tactataact aatataagta caaaatttaa gagaaaggat gttaatctac tgtgattgaa
      841 tcaattttat tagttacttc tctttgtata gatgcctttg tgacaagctt tggatatgga
      901 gtaaataaag ttaaagttcc cttatattca aatataatta tcagcgtagt ttgttcagct
      961 attttagcaa tatcgctttt tgcaggtaca atagttagag attttttacc tcaaaatata
     1021 acaatgttaa tatgtttctt tattttattt ttattaggaa gtgctagact aattgaaagt
     1081 ttttttaaat cttattttaa gaaaaaatct atacactcaa agaattataa ttttaatatg
     1141 ttagaccttg aattaaattt taatgtaagt atcgaacctg atgtcttaga tacaagtaaa
     1201 tctaaagtgc ttaaatctgc tgaagcattt acacttgcac ttgctttaag tttagatgga
     1261 ttagctatcg gttttggtag tggccttgta ggtgtgaatt atatacaagt tattctattt
     1321 tctttaatat caaatataat tgcagtatta cttggttgtt tactaggaaa tatgtttgtt
     1381 aaaaacgtaa atttaaactt atcttggtta agtggtttaa tcttgttagt cattggattt
     1441 atgaagatat gttaataaga aagcaatcta aagataaact tttctcttta gattgctttc
     1501 ttttgtgctt tttatattta ttttctattc tctctaattt ctttctgaat ctttttaaga
     1561 gctttttttg aacctctttg aatatctttt tctaattttc tttctttaaa actagtaaat
     1621 aatacatcta aatcataccc ttctggatac aattctgatg cttttatgct aagttgtaat
     1681 ctttttatat ttactgaaat aaaattatca ttaaacaata cttctacatt attaaacttg
     1741 tccataggct tatatacaat tccaaaatca tcttcatcta gtaattttac cttatcccct
     1801 acattataat ctgtatagct taaaatgact tcagaactat ttttatcttc aatattagat
     1861 tgtagcttac ttcttttaac taaatctaaa ttgtagtttc tatcaattac atattcttta
     1921 gctctatcta aaactctatt ttttattccc atttttttag aaataaaaag agcattacta
     1981 tcttcagatt ttccaatagt taacttatac aatggttcta acgtttcttt atcaaacatc
     2041 ataccagcat tttcaaattc tggatgtaat gtagcaaact tttttatctc tccataatga
     2101 gttgatgcta tagttataca tcccattttg taaaactctt ctaataatga tattgctaaa
     2161 ccagctcctt cattaggttc agttccactt cctatttcat caaacagaac aagagtagaa
     2221 ttatttgata aactcataat ctctgcaata ttttttatat gtgatgaaaa agtacttaag
     2281 gcattttcaa tactttgatt atcccctata tctacaaaaa ctttttcaaa tacactaaat
     2341 tcactacctt cttttgcaga aatatcaaat ccacattgaa ccattaaagt tagtaaacca
     2401 acagtcttaa gggttacagt ttttcctcct gcattaggac ctgttattat aagacttcta
     2461 taatttttgc ctatttcaaa atctaaaggt actgcatctc ctgttagaag tggatgttta
     2521 cctttaatta tttttatata gccattatta tttatttttg gagtaattcc ttttattttt
     2581 tgactatact tagcttttgc aaataccata tcgtattctg aaagtatctc tatatttaat
     2641 tttatctgac ttatcttctc aaatataagt tctgttaaat aagataatat tttgtattct
     2701 tcaatagttt catcagcttt tagcatagtt aactctgtac ttaaatttga aacactaata
     2761 ggttcaataa atacagtatt tccttttgat gatgtatcta atatagtacc attaacttca
     2821 tttttataag aagatttaat tggtattaca tatctatcat ttcttttact tattataaac
     2881 tcttgtatat actttttatt tacagttgat gttataaatt tatttaatct atcttttatc
     2941 tttccttctg taatttctat atttcgtctt atctttttta attctttact agcattagaa
     3001 tcaactttat tagattttat acagtaattt atctcatctt ctatactttt acattctgtt
     3061 atatttaaag cataagaact taatgtaggt gaataaaatt ctttttctaa cataaaagct
     3121 ttcatcttcc tacaacctct taaaaaatct tcaatattta caagttcaac aggttctatt
     3181 atcattcctt tttcaatttt atctattgta gaacctgcat taaacaatcc ttcaagtggt
     3241 atgtgattac tattttcaat tatctttcta gcttctttat tttctgctaa tttccttctt
     3301 actactccaa tattcccact aggagttaat ttatctatta aattttttcc tagcgaactt
     3361 acacaatgta tttttattaa gtctttaact tcatttagtt gcaatctttc aaatgtatta
     3421 ctattcatta ttttttctcc tttatttata agtcatcgtc ttttaaatca ccctatcatt
     3481 tactttgata atagttattt tgcgaacaac ttaataaata aggagttatt atatatcaaa
     3541 ctccttattt attaagaagt ttaactccgg actcattaat gttagtattt tttttcataa
     3601 aacacttctc cttttctatt cttatttaaa cacttatacc agtgcttcta atattattcc
     3661 ataaattata tatttatgtc aataaaaata atgttattaa tgtttttgta cagtgaaaat
     3721 ttttatagtg aaaataagct tatactttca tttatatttt ggaattactt atattgtcat
     3781 caattcatgt atgtgtagtt tccaatacaa tctaactttg taatcattat atatcaaaga
     3841 atttagctct ataaattatc gtctctataa aataaaaaaa tagctaataa taataaaaca
     3901 cttttaaatg ttccataaaa ttagctattt ataatataat tttaatcttt tttaacttta
     3961 aaaattatcc tttataagta atcaatggct tcatagttgc cactacttga ataagttcat
     4021 attctatcaa actttcaata atctgctcta tattcttata tgcctctgga gcttcttgaa
     4081 ataataaatt tacatcatta catataatct gacttttaaa tttagtttgt tttatagtat
     4141 ctttactata cttactttta aggcgcgatt tacaaactga acgagaccat tttctacctg
     4201 ctccatgtga tagagaatat aaagatatct ctgtattttc agtaggcata actatatatg
     4261 atagactgcc tcttgaacct ggtataatca cagctcctct ttcacttgaa acagcacctt
     4321 ttctatgtat aaatttatct tcccttttct ctataaagtt atgatttata gagaatattg
     4381 tttcaacatc ttcagatgta cctattgact gcataatttt tttactgata gcttcacgat
     4441 tacgctctgc ccacattaaa gcattatcat gttttttaat ataatctatt gctttctcac
     4501 tttcaacttc aagtccatct ttatcataaa atttttttaa aatatcttct ccataatttc
     4561 ttgacccaca gtgaactaac atcataatat catcagatga aaattttaat tgttcaaatt
     4621 gttctttatt ataaatttca cttatacatt gaatttctac aaaatgattt ccactcccta
     4681 tagttcctaa atttaaaatt ggacattctt ctttatatgt gttttttatt tctatatcgg
     4741 acaaatcttt aatcttacta agtgacttaa tccatttgtc ttttttaaat ttctttttta
     4801 gaaccccagt tttaaataaa gtcattccgc atcctatatc atttccaatt atatgtggat
     4861 aaataatatt tttagtctca actgctaaac ctacaggtat tttacctgta tgtaagtcag
     4921 gtaatcctac tactcttaaa attccattta actttgaaat atcttctagt tgtttccttg
     4981 ctatatcttc aatccaacat ttattacttg ctattatttt tatattgctc ataatttgct
     5041 cctttttaat attctcctgc ctttaaaaag tagcaaaaag ctgtgacctt tagccacagc
     5101 ttttttattc taaactgtaa aagcaggtgg ctatttgtta aaatactcct agacgtttaa
     5161 tacctcatta ttttttgtta acataataac cacttccttt cataatttaa gactacacta
     5221 aaatttctat gtatatcatt tatagacatt gattttaaaa tacttaatat acaattttta
     5281 tattatggaa ctaataataa tcattgaaat catgactata gctagaccgg caacaacaag
     5341 ttttttatgt aatttttttc tcattttact tttatattct tttttaactt gtataacttt
     5401 gtcttgtttc tgttcttctt ctttctcatc ttcaacttct atatatgctt tttcatacat
     5461 tactttactt aaatcaataa taatatcatt ggctctagta tacttattat ttcttccaag
     5521 aagccttttt ataacattta taagttctgt atttccatta attgctttta tactattcca
     5581 atctaatccc ttatcaatag attgtagcat tttttcttct gaatttgatt ctccaaaagg
     5641 caatttttta aatatagatt caaatagaat aagacctgtt gcaaaaaaat cactttcttt
     5701 atcagtataa tttatacata gttgatgtgg gcataaatat ctcctgtttc catagcttct
     5761 tgtattaacc ccattatttg cttttgtaat tccaaaatca caaattttta tattgtattc
     5821 tgtatctact attatactac tcgattttaa actaccatga tatgaatgat tcctatgtat
     5881 catttctaaa gcttttaaaa cttgtatcat tatgtttaca attgcttcta aatgaagata
     5941 attacctaga attaattcat ctagtccgat accattaaag tcttcactta caacataata
     6001 taatgttgtt tcttctgtac agtgaatccc aacatctatt atttttagta tataaggaga
     6061 gtttatctca tctaaagcag tactttcatc aattaaattt gaaacaaaat cttcacaaat
     6121 ataattattg tgctttataa cttttattaa cacatttctc ctgtaaaaaa catctctagc
     6181 tttatagatt ttgttaattt ctaaaacgtc atcagaattt actacctcat atctattgcc
     6241 tataaaattc aaccatgtca cctcctcata cattttatat aactaaatct atttacaatt
     6301 ataccaatat ataggaatat tttctatata ttaatgattg taatattaaa acaagaacta
     6361 atagtgttaa tttttacaaa aaaggctgtc tcaaaataga gatacgcttc ttttgtattg
     6421 ttgaaatgat gaaaatatat ttgatttcac ataaaaagag tgtctcataa actaaaaagt
     6481 tcattttgag acactccctt ttatattaca aatatttctc taaaaaatta tctatttttt
     6541 taattcttta taagaactat ttgatatatg ttcttttttt atgacctttc cacttgaatc
     6601 tttaaatatt cgatatgtag aatatttatt ctgaccagtt tgttttacct ctatagatat
     6661 atttggtttg tcaccagaat taccatagat tactgatgat acacttcctc cacctgcata
     6721 atttttaata tatacaggat gcttatatgg atttttaaac tttaagttta atcctccatc
     6781 gctcacagta gcatctcttc ctttaggcac ataagtagat gcagatgaat gatttgtaac
     6841 ttgagttatc tccatacccg aaagaagagc cgcattataa actgttgaag atgtttgaca
     6901 aacacctcct cctgctgatt gttctagctt accataaact ataacaggtg catctttgta
     6961 accatttgct ttattactag gtcctgtaag tttattgtat gaaaattctt cacctggcat
     7021 taataataca tcactagttt ttcttgctga taatcctaca ttatatgacc taccctctac
     7081 agcttgtgaa taagtagttg aatattgacc tataacagaa tttacagttt ttacttgttc
     7141 agttgttata tctggttttt gaagatttac tttaagttct aaagttttat gctctttatt
     7201 ttttatcata ttatatatag actctttatt tgctgccaaa tcaaattctc tacctacaac
     7261 agagtctgta taacttagtc caccacttcc aacactaata gaagcatttt tcatcttaac
     7321 atttatacta tctgctattg aagacacttt ggaactaagt tttgcctcat catattcagc
     7381 ttttatcttc atatttgcct tattcactct tatatcaata tattttttta agttttgaaa
     7441 ataggaccct ttttttgtac tttcataagc atcttttaca acatcttctg tatcatattt
     7501 taaatcaata tcttttggtg atattgtata ttttttccca tcataagtaa gatttaagtc
     7561 ttctggagta tacttatctg ttatagcttt taatgcctct gctttagtca tatcagatac
     7621 atttactcct tctatatata catttttagc gattttccca ttgtacagaa atttactgtt
     7681 aaaaaaataa gtaaatccac ccattattag aactaaagct gccaatacaa ttaaaacact
     7741 tcgttttttt tctttaccta atcttgaaac tcttgttgtt cttctgccca taacttcacc
     7801 tcattttgac actagcttaa atttgcataa tagagttccc atttcaaaac taccttagat
     7861 tatatttgaa tagcttttgt taaacaagga atttaatcaa atgtaacttt attgtaaatt
     7921 tatgtcttat aattagtttt atttttgata ttttttatta tatttctttt actatttctt
     7981 aacaaaaaat tgtttatttt ataacaacta atttcattta tattgaaatt taaatgtaac
     8041 ctattacagg ataatggtct gacaggtaaa ttttttctac tgtgtatcct tttaattcag
     8101 tatttttatt aacaaaaatg taatctattc tagagtttga tttttcaaat gttggtaagt
     8161 aagacttgtt tagtgaaata gccatatcat taaacatact taaaaagaca tttttctcat
     8221 taaaatcacc acataaaata actatcccca ctaatctgtt cctatagtct attatttcgt
     8281 ctaattgttt tgctctctcc tgcctatcaa gtcccaagtg agtatttatt acatttataa
     8341 ttcttccata tgcatctata gttatacaaa gagctccccg ttgttctttt ttgctagtta
     8401 agaaaaaatg attactgttt aacattttag atgttgtaaa tgtacaaata ccatatatca
     8461 tatttacttt ttttacattt gtagcaaaga caccatccat atttaaaaca gcttttaaag
     8521 ctaaaaattg aggatataat acttcttgca aacaaattac atcacaatcc aattgtttta
     8581 aatataaccc cattttagtt agagttaatc tattatttga atccatacct ttatgaatat
     8641 tgtaggttac tattttcata ataatatcac ctcttatgca atataatact tactaaaatt
     8701 taaacttatt tacttttcac ttaagaccat tatttatctt ataaaattga gtacttataa
     8761 actttatcac aaaaaaacct aacttaagta tttatattct acataagtta ggttttataa
     8821 actattataa tatttattat ttcattcatt tctaatgatg attctccttt tttatctttt
     8881 tcaatttgcc ttcactaaca acaaataaaa atcccatctt cttgtatatt tcatccaatt
     8941 caattaaagt tacttcacca ttttttaaat ttgttaatgt tatatcttgt attcttcttg
     9001 atggaattat cataagttat caacactcct ttaaattctt tttaatcttt atatttaaat
     9061 atatttatgc attctgatat atattcataa attattaaaa taaattcaaa aaacacccgt
     9121 tctgcaaaca ttcgttctgt atatttatta tacatcatac agacgttcga ttcaatataa
     9181 aaattaaata tatctcgttt ttagtaaatt ttacaatatt atacactaaa tatgtcaaaa
     9241 catcttcttg aaatagatta tcttgtcaaa caaaaaaaac catttcagta aaagcttctg
     9301 cttaaattga aatgactttt cttatttaaa ttattaattt tataccatat ttttattaag
     9361 ctaacatatg taatatttga gttaccacaa gagcacaata agtccctata atatttccta
     9421 gaagccccat aagtacacct actggtatta atacaggatt gtgaacccca gcaatcattg
     9481 gagctgtagt tactcctcct atattagcta tacttcctac ttcacaagta aataaatcaa
     9541 gtttaaatag tttagcaagc cctataaatg aaatagcatg tacaaggact actaccaatc
     9601 caaacattat gtaaacaggt gcttctgaca atccaaagaa atttgcttta ctacctgtag
     9661 ctgcaaggag taaatacata aacacatttc ctaccagtgt actcccttta agctttgata
     9721 tttttgtcat acccaataat attgatactg tagatgcaac aagtactacc cacatagttt
     9781 cattaagtat acctgaagtt ggaagtatct tggatacaat ttgtgcaaaa gacgcaactc
     9841 caaacccaac agaaagtaaa atcataagtt ctacaaacgt aggtgccgta ttatctttat
     9901 tttctttttc aagttttgat gtaacctcat ctataaaact tgtatcgcac tttgtccatt
     9961 tgttaaattt aggtccaaat ttcacagaca ttagacaaac agacatccat actgtatatc
    10021 ctatagaacc cataagtatt gcataactaa gtccttcttc tgcaactcct agagcattag
    10081 ctgctgcaat catatttgat gagccaccta tccatgaacc agatgctgcc ccaagaattt
    10141 tccatgaatc tgcacccatt gaatttttaa aaattatgaa tgctataaca aatccaagca
    10201 taaatgtaaa tgtagcacag aaaaatgata ataacatttt aggccccatc tttaatattt
    10261 ttcttaaatc acattgaatt aacaagaaca ctaacattaa tggaaggaag ttcactgtta
    10321 ttatgttttg atacgttcca acatcttcat tctgtgcaaa taaaccaaat gatccaagta
    10381 tagctgaacc taagtatatt aaaagcattg gattaataac atcaaatacc ttccatttca
    10441 atttatcaac cataaaaaaa attacaccta cgaatacaac caagaaacta caatatacaa
    10501 atccagtctc aatcacatta tacacaccct ttcttttcct aattaatttg atttttatga
    10561 tttctaagta aagacttttt cagataatag acaattaaaa taaatacttt tatctatatc
    10621 atgctaatta aatacatata tacctaacta ttgacatata ttaataaaga ttt
//
LOCUS       DAMJYN010000107        10332 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.112, whole genome shotgun sequence.
ACCESSION   DAMJYN010000107 DAMJYN010000000
VERSION     DAMJYN010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10332)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10332)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10332
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.112"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            180..959
                     /locus_tag="PC466_003215"
     CDS             180..959
                     /locus_tag="PC466_003215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HDF2770572.1"
                     /translation="MNYKKIAIITGANSGFGKEFLKLLINEEEITEIWAVARNKARLN
                     QLVDEFGSKVKVFSKDLSKIEEVKEIGTFLSKENVCIKYLINNAGFAKFCSYNDLSID
                     ESINMIDLNISAVVVLGLICIPYMQKGSHIMNISSQASFQPLPYQNIYSSTKAFIRNY
                     TRALNVELKSKGINAIAVCPGWMSTNLFKRGIVVAEKGTKNFPGIVSPDVVAKKALKD
                     AKKNKDISVYGINTKSSHLLAKLLPQKMMMKVWLMQQHIKE"
     gene            complement(1269..2090)
                     /locus_tag="PC466_003216"
     CDS             complement(1269..2090)
                     /locus_tag="PC466_003216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002572585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallohydrolase"
                     /protein_id="HDF2770573.1"
                     /translation="MKLKIVGSGGMSIIPSSFCKCKICEEARQKGGRYERLGPSLYID
                     DIKMLIDTPEDITVACNRQKISEVKHISISHHDPDHVKGIRIVEKIGCDFITGENNPI
                     GFYALPEVIEDINRTNLDCLKYYGDVINCISINETSHVKINNFDIDLINNNPDRNITF
                     YVIKENEKKVIYACCNPKPFTHSDMYFDADVLIISLVSDDGILNDGTKLEDTPFKDEI
                     FTLDEIVEIKNYYRIKKIIITHIDEMWGKSYGYYSELEKKLDNIYFAYDGMEIIV"
     gene            complement(2815..3633)
                     /locus_tag="PC466_003217"
     CDS             complement(2815..3633)
                     /locus_tag="PC466_003217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF2770574.1"
                     /translation="MFKIGDFSKLSKISIRMLRHYDEIGLLTPSHTNNTNGYRYYSAD
                     QLSTTNRIHALKDMGFGLYSIKEILTEYNDKESLIKYLNIHHSQVKEQLEDTQKKLLK
                     IETTIKRIGGNDIMKNYDVTIKNFAPKYMMTLRRVIPTYQDEGMLWHQAFLETKDQNV
                     QIEPPKYSKAVFYDTGYKEDSVDVEVQVAVSGKYKDTEHVKFKTVPSVTAATAIVNGN
                     FNQVADACEAIGNWISDNNYDVDGPMFNIYHVSPGNDSNPDNWVTEVCFPVKKK"
     gene            3801..4382
                     /locus_tag="PC466_003218"
     CDS             3801..4382
                     /locus_tag="PC466_003218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2770575.1"
                     /translation="MKSNDKDARERIIEVTLNLLNEVDDIEEITVRKIAERANVGVGL
                     INYHFKTKDNLLSTAIGDVMSNIIAELYDDSVYTLRPIEDLKNLLKKLCDTGLHYEKV
                     LPFVLNQCITNGDMQAELDIVPMLRKIFGNKKDEMSLRIIALQIILPIQISALSTESF
                     QLYSGINIKNKYERDKFIDILIENIIGEDVDVR"
     gene            4379..4573
                     /locus_tag="PC466_003219"
     CDS             4379..4573
                     /locus_tag="PC466_003219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770576.1"
                     /translation="MKIITIGSSLITVLLFLSTMVCGFWIKNNKVTDASSIKFHMNSA
                     IFTGIFLLISTILLIIYIKK"
     gene            complement(4737..6479)
                     /locus_tag="PC466_003220"
     CDS             complement(4737..6479)
                     /locus_tag="PC466_003220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M3"
                     /protein_id="HDF2770577.1"
                     /translation="MVKSKKKIFVFLILIAVFIIFASYIRNYTNDTKKDSVRGTIPFE
                     KMEYKRPNIQSICENINKCNDKLLTAKTAKEQLNLFNEVDKIYQDFYSTLTIAKIRNN
                     IDSSDEFYSKEYKYLMSKSVDVDMSYKDFQDRFVTSKFSKELEKELGKDTFNYLKNIG
                     KLNSKEVEDLLKKEQDLVVKYEDLLAKSTVSIDGIEVDFEEALSRPNLSPEEYVKIYS
                     DYLKKYNPIFGNIFLELIQTRTEIASKQGFKNYIDYAYMNLNKDYSQEEAKKFRQDVK
                     DYIVPLYREISSKPSDSSIYIKVYKNRSFRKFDKVLEDISPKLKESFDYMKKYDLYDY
                     SSGKNKSPGGYTTYINKYKAPFLFNTWDNSFLGVTSFAHEFGHFYNYYNSINLNNKMQ
                     PSIDVCEVHSTSLEILFYKYFDDFFGKQSEAIKKEHLSIVLNTIIDACLYDEFQEIIY
                     KNPYMSLNDINKLFFDLEEEYGVSNNILREKNAPFWILVSHNFQVPFYYLSYGLASDV
                     SLQIWQLSQEDYRKAVDVYMDFLNQNTDAGFKDVVEKVNLQLPFQDGNLEEISSTLYD
                     YFGIDNPLELKNAS"
     gene            6908..8284
                     /locus_tag="PC466_003221"
     CDS             6908..8284
                     /locus_tag="PC466_003221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk family potassium uptake protein"
                     /protein_id="HDF2770578.1"
                     /translation="MKTIVRRLILYADGMRPTQIMVSGFAAIIVIGALLLTLPIASQS
                     GESIGLLNALFTATSAVCVTGLVMVDTATYWSLFGQIVIITLIQIGGLGFMTVATMFS
                     LMARKKIQLRERLLIQESLNQADLSGLVRLTRFVLIITITIEGIGALVLSTVFIPQFG
                     LSKGIWYSVFHAISAFCNAGFDLMGSVSGPFTSLNSYVNNFTVSMTVCALIVLGGLGF
                     PVVLDIVRKRRFSKLNVHSKVVLFSTATLIFVGALFIFLIEFNQKATMADLPLKGKVL
                     SAIFQSVTARTAGFNTLDLATLRESSVFVMIILMFIGASPASTGGGIKTTTLAVLIIT
                     VRSFLSGKSDIEAFERRLAPSTIKKSLGIFVISISAVIFGTLIISITQPNFTLVQSAF
                     EVTSALATVGSSLAGTPNLNALGKIIIIIFMFMGRVGSLTLFMAILSGGRRKSQPIRY
                     AEGKIMVG"
     gene            8595..9266
                     /locus_tag="PC466_003222"
     CDS             8595..9266
                     /locus_tag="PC466_003222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HDF2770579.1"
                     /translation="MKQYIVIGCGRFGSSVASTMHLLGHQVMAIDKNEDSVQSISDKV
                     THSLIVDVTDEQALRSLGLGNFDVAVVAIGSDIRASIMATLIAKEMGVELIICKAKDE
                     LQAKVLYKIGADRVVFPERDMGVRVAHNLVSDNILDHIELDPEYSIVEIVTPNSWVGK
                     TLIELELRARYEITVLAIKTGKNINVTPSPDEELTAGSILVIIGQNTSITAITSGNKG
                     IIRRR"
     gene            9457..10254
                     /locus_tag="PC466_003223"
     CDS             9457..10254
                     /locus_tag="PC466_003223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HDF2770580.1"
                     /translation="MITNINSKDNEKLKYTRALLKSKNRNKESKFIIEGYRIVMLALE
                     CMANLDYVFINEEFENKKEHVKLLEDLDKKNTKIYKTTNKNFKELVDTENTQGIIGVV
                     SFKKKKLSESINKKDKFVLILDRIQDPGNMGTIIRTADSAGVDAIIALKGCVDIYNPK
                     VIRSTMGSIFDMNIIDASQDETVDMLKSLDFNIVSSYLNTENFYDKIDYGSKVALVIG
                     NEANGINEELVSKSDILVKIPIYGKAESLNAAISSAILMYEIKKYLI"
BASE COUNT         3822 a         1247 c         1574 g         3689 t
ORIGIN      
        1 taatcaatac tgattctata atattaacac tattttttat gctatataac aattattgaa
       61 aatgatataa atataatatc tcaaatgata tgaatataac atctgaatag agggtgtttt
      121 atttgtaaaa aataagttta cagtttgagc gtataaactt atggtaaagg agaataatta
      181 tgaattataa gaagattgca attataacgg gtgctaatag tggttttggt aaagagtttc
      241 taaagttatt aataaatgaa gaagaaataa cagaaatatg ggcagttgca agaaacaagg
      301 cgagattaaa tcaattagta gatgaatttg gaagtaaggt aaaagttttt tcaaaagatt
      361 tatcaaaaat agaagaagta aaagaaattg gtacattttt aagtaaagaa aatgtatgta
      421 taaaatacct tataaacaat gctggttttg caaaattctg ttcatacaat gatttaagta
      481 tagatgaatc tattaatatg attgatttaa atattagtgc tgttgtagta ttgggactta
      541 tatgtattcc atatatgcaa aagggaagcc atattatgaa tatttcttca caagcatcat
      601 tccagccatt gccatatcaa aatatttata gttcaactaa agcgtttata agaaattata
      661 caagagcatt aaatgttgaa cttaagagta aagggataaa tgcaattgct gtatgtccag
      721 gttggatgag tacaaatcta tttaagagag gtatagttgt agctgaaaaa gggacaaaaa
      781 atttcccagg catagtgtct ccagacgttg ttgccaaaaa agcattgaag gatgcaaaga
      841 aaaataagga tatttctgtg tatggtataa atacaaaatc cagtcattta ttagcaaaac
      901 tattgccaca aaaaatgatg atgaaggttt ggttaatgca acaacatatt aaggaataag
      961 agtttcggta attaagtatc agttggagat tcaatctatt atatattata agaagttttg
     1021 ttgagcaaat aataattgtg acaaaacggc ttatctagtg ccgataagcc gtctataatg
     1081 tataaaaaat atatttttga ttttacttta tttagatatt gaagtattaa aatatgtagg
     1141 acttgaaatt ttataaagat aaatactatg atattttgta aaaactgaga tatgttgata
     1201 ttacatagtt taactatact gttaaattga agttttctta ttttgcatta tgcttattac
     1261 ttaatgattt agactataat ttccatacca tcatatgcaa aataaatgtt atcaagtttc
     1321 ttttctaatt cactgtaata accatatgat tttccccaca tttcgtcaat atgtgtaatg
     1381 ataatctttt taattctata atagttttta atttcaacaa tctcatctaa agtaaatatt
     1441 tcatctttaa atggtgtgtc ttcaagtttt gtaccatcat ttaatatacc atcatcagaa
     1501 actagactta ttattaaaac atcagcatca aagtacatat cactatgagt aaatggcttg
     1561 ggattacagc aggcatatat gacttttttt tcattctctt tgataacata gaaggttata
     1621 ttcctgtctg ggttattgtt aatcaaatca atatcaaaat tatttatctt tacatgcgaa
     1681 gtttcattaa tagaaatgca atttataaca tcaccataat atttaagaca atcgagattc
     1741 gttcggttta tatcttcaat tacttcagga agagcataaa agccaattgg attattttct
     1801 cctgtgataa agtcacatcc tattttttcg acaattctaa tacccttaac atggtctggg
     1861 tcatggtgag aaattgaaat atgttttact tccgatattt tttgtctgtt acaagctact
     1921 gtaatatctt caggtgtgtc tatcagcatt tttatatcat caatatataa acttggtcct
     1981 aatcgttcat atcttccgcc tttttgcctg gcttcttcac atattttgca tttacaaaat
     2041 gaacttggaa taattgacat accgccacta ccaacaattt ttaatttcaa agttattaca
     2101 ccaccttcta aaaatattag attatataaa taatctacaa tcacaactga ttaacaaaat
     2161 tatgagttaa taaattatat cacatgtaaa tatgaaagaa tagtatgaaa tttttataag
     2221 attatattaa atatttctca atgaaattga ctttgtatat gagccgaatg actttattca
     2281 atatagataa gacatttttc ttgtaataag atatgattat tctataaggt tcatgtaatt
     2341 ttgatataaa atattgatta ataacatata tgttattggt gaacatattt ctatagaatg
     2401 gaatatataa ttttttatat ttatcattgt attattatac aaagaaagtt aaaaagagta
     2461 gagtacaaag gaattatttg tactttactc tttgttttgt taaaaactaa tttatattag
     2521 tgattcaaat atttaactag agtataaggg ttgtatataa tcttataagt aatttatctg
     2581 acaaattaag ataatatcct aatcaaattc tagtcattcg aacataacat cacaagtgat
     2641 ttatctgaca aattaagata atatcctaat taaattgtag atatttatac ataacactaa
     2701 aagtaatttg tttaacaaat taagataata tcctaattaa attgtaggta tttatacata
     2761 atactaaaag taatttgttt aacaaattaa aatattatcc aattaatata aaaattactt
     2821 ctttttaact gggaagcata cctctgttac ccaattatca ggattactat cgttgccagg
     2881 acttacatga taaatattaa acataggacc atccacatca tagttattat ctgatatcca
     2941 attaccaata gcctcacaag cgtctgcaac ttgattgaaa tttccattaa caattgcagt
     3001 tgcagcagtc acacttggaa cagtcttaaa tttaacatgt tcagtatctt tatactttcc
     3061 agatacagca acttgtactt caacatctac agaatcttct ttatatccag tatcataaaa
     3121 gactgcttta gaatactttg ggggttcaat ttgaacattc tggtcttttg tctctaaaaa
     3181 tgcttgatgc cataacattc cttcgtcttg ataagttggt ataacccttc taagtgtcat
     3241 catatatttt ggtgcaaaat tctttatagt tacatcataa tttttcataa tatcatttcc
     3301 tccaattctt ttaatagtgg tttctatttt taatagtttt ttctgtgtat cttctaattg
     3361 ttcttttact tgagaatggt ggatatttag atattttata agactttctt tatcgttata
     3421 ttctgtcaaa atttctttta tagaatacaa gccaaagccc atatctttta gtgcatggat
     3481 tctatttgta gtagaaagtt ggtctgcact atagtatcta tatccattag tgttattcgt
     3541 atgagaagga gttaaaagtc ctatttcatc ataatgacgt aacatacgaa tactaatttt
     3601 acttagcttt gaaaaatcgc ctatcttaaa catgtttttg tctcctttat aaaggtactt
     3661 ttagcttaat attaatataa accatatcat aatgttagag tcaactaaaa ttataattaa
     3721 attatattga catatgatga aaaaaatatt atactgaaca tgttcagaac ctaaaatgtt
     3781 aattattttg gaggtctatt atgaaaagta atgataaaga tgctagagaa cgtataattg
     3841 aagttacatt gaatctttta aatgaagtag atgatattga ggagattaca gttagaaaaa
     3901 ttgctgagcg tgcaaatgtt ggagttggtt taataaatta tcattttaaa acaaaggata
     3961 atttgttgag tactgccata ggagatgtga tgtcaaatat aatagcagag ctatatgacg
     4021 atagtgtata tactctaaga cctattgaag atttgaaaaa tttattaaaa aaattgtgtg
     4081 atactggatt acattatgaa aaagtgcttc cttttgtgtt gaatcaatgt ataaccaatg
     4141 gagatatgca agcagaactt gatattgtcc ctatgcttcg taaaattttt ggaaataaaa
     4201 aagatgaaat gagtctaaga atcattgccc tgcaaattat tttaccaata cagatttctg
     4261 ctttatctac agaatcattt cagttataca gtggtataaa tataaagaat aaatatgagc
     4321 gagataaatt cattgatatt ttaatagaaa atattattgg agaggatgtt gatgtaagat
     4381 gaaaattata actattggtt caagtcttat cactgtttta ctttttcttt caactatggt
     4441 ttgtgggttc tggattaaga ataataaggt aacagatgca agttctatta agttccatat
     4501 gaatagtgct atttttacag ggatattttt attgatttcc acaatccttt taattatata
     4561 tataaaaaaa taataatatt attaataaat aaagtatcag aaattataaa gacaagagtc
     4621 ttaaaaattt ctgatacttt accacataat tttattaaac attaattgtg tgtgaaaaaa
     4681 tatcacttat ttcaatctaa tactaaatct taagagtgag tataaagtat tagaaattaa
     4741 gaagcatttt ttagttcaag tggattatct ataccaaaat aatcatataa agtagagctt
     4801 atttcctcta aatttccatc ttggaaaggt aattgtaaat ttaccttttc taccacatct
     4861 ttaaatccag catcagtatt ttgatttaaa aaatccatat atacatcaac agcttttctg
     4921 taatcttctt gtgataattg ccatatctga agtgatacat cagatgcaag accataactc
     4981 aagtaataaa aaggaacttg gaagttatga gatacaagta tccaaaaagg agcatttttt
     5041 tctctaagta tattattgga aactccatat tcttcctcta aatcaaaaaa caatttattg
     5101 atatcattta gactcatata tggattcttg tatataattt cttgaaattc atcataaaga
     5161 caagcatcaa taatagtatt taaaacaatc gataagtgtt ctttttttat agcttcagat
     5221 tgtttaccaa aaaaatcatc aaaatattta taaaatagaa tttctaaaga tgttgaatga
     5281 acttcacata catctatact tggttgcatc ttattattta agttaatact gttgtagtaa
     5341 ttataaaaat gaccaaactc atgagcaaaa ctagtaacac ctaaaaaaga attgtcccat
     5401 gtattaaaca agaaaggtgc tttatattta tttatataag tagtatatcc tccaggcgat
     5461 ttgttttttc cagaagaata atcgtacaag tcatattttt tcatatagtc gaagctctct
     5521 tttagttttg gagatatatc ttcaagtact ttatcaaact tcctaaatga gcgattttta
     5581 tatactttaa tataaataga agaatcagat ggtttagatg aaatctctct atataatgga
     5641 actatgtaat cttttacatc ttgtctaaat tttttagctt cttcttgaga atagtctttg
     5701 tttaggttca tataggcata atctatataa ttcttaaatc cttgcttact tgctatttca
     5761 gttcttgtct gtataagttc taagaatatg ttaccaaata taggattgta tttttttaag
     5821 taatctgaat aaattttcac atattcttca gggctaagat ttggtcttga caaggcttct
     5881 tcaaagtcta cctctatacc atctattgat actgtagatt tagctaataa gtcttcatat
     5941 tttacaacta ggtcttgctc ttttttaagt aaatcttcaa cttctttaga attaagtttt
     6001 ccaatgttct ttagataatt aaatgtatcc tttccaagtt ctttttctaa ttctttagag
     6061 aatttagaag ttacaaatct atcttgaaag tctttgtatg acatgtcaac atctactgat
     6121 ttactcataa gatacttata ttccttagag taaaattcgt ctgatgaatc tatgttattt
     6181 ctaatttttg ctatagtaag tgtactgtaa aaatcctgat aaattttatc aacttcatta
     6241 aataaattta attgttcctt agctgtttta gctgttaaaa gtttgtcgtt acacttgtta
     6301 atgttttcgc aaattgactg tatattagga cgcttatatt ccattttttc aaaaggaata
     6361 gttcctctaa cagaatcttt ttttgtatca ttagtataat ttcttatgta tgatgcaaat
     6421 ataataaaaa ctgcaattaa aattagaaaa acaaatattt tcttcttgga tttaaccata
     6481 aaaatcctcc aatcatggat atagttatta attattttac tatattaaat ataaaaaatg
     6541 catgttaaga aaatttaaca taaagatata gataagatta taaataatat aaaaaattta
     6601 acttcaaaaa agtatatgaa atttatactg gtaaaatgat aaataaattt taagtacaaa
     6661 atagtaaaag ctatgatagt tttagaccca ttatatgtaa aaaatataga tgtttttggt
     6721 gcaatttaaa ttaaaagata tatataaaaa tttaaaatat tccaaacaga aattataaaa
     6781 attactatca ttgtctttat gcaatattta tactataata gaataataat ttagaggaaa
     6841 gctctaaaaa taaacaaatt aagggtctta acagtagtga ttttatgtta aggaggtata
     6901 aagaaagttg aaaacaatag ttagaagact tattctctac gcagatggaa tgcgtcctac
     6961 tcaaataatg gtatctgggt ttgctgcgat tattgtaatc ggagcattgt tgttaacact
     7021 cccgatagcg tcgcagagtg gagagagtat aggcttatta aatgctctat ttacggctac
     7081 ttcagcggtt tgtgttactg gtctagttat ggtagataca gcaacttatt ggagtttatt
     7141 tggacagata gttataataa cattgataca aattggtggt cttggattta tgaccgtagc
     7201 cacaatgttt tcacttatgg cacgaaaaaa aatacaacta agagaaagat tattaataca
     7261 agagtcatta aatcaagctg atttatcggg acttgtaaga cttacaagat ttgtattaat
     7321 aataaccata acaatagagg gaataggtgc actggtttta tcaactgtct ttattccaca
     7381 atttggtttg tctaaaggga tatggtatag tgtatttcac gcaatatcag cgttttgtaa
     7441 tgccggattt gacttgatgg gcagtgtaag tggcccattt acatcgttaa attcttatgt
     7501 aaacaacttt acagtatcaa tgactgtttg cgcacttata gtgcttggag ggctaggatt
     7561 ccctgttgta cttgatattg taagaaaaag aagattttca aaattaaatg tgcattctaa
     7621 ggttgtattg ttttcaactg ctacacttat ttttgtgggt gcattattta tttttcttat
     7681 agaatttaat caaaaagcta ctatggcgga cttgccttta aagggaaaag tactatcagc
     7741 aatatttcaa tcagtaacag caagaactgc tggttttaat acacttgatt tagctacttt
     7801 acgagaaagt agtgtatttg taatgataat tttgatgttt attggagcat cacctgcatc
     7861 aactggtggg ggtataaaaa caacaacact agctgtttta atcattacag ttagaagttt
     7921 tctatcagga aaatcagata tagaagcttt tgaaagaaga ttagctccat caactataaa
     7981 aaaatctctt ggtatatttg taatcagtat atcagcagtt atttttggaa cattgattat
     8041 ttcaataact cagcctaatt ttacattagt tcaatcagct tttgaggtta catcagcact
     8101 tgctacagtt ggttcaagtt tagctggaac tccaaattta aatgctttag gtaagattat
     8161 aataataatc tttatgttta tgggtagagt tggttctctt actttattta tggctatact
     8221 ttctggtggt agaagaaaga gtcaaccaat cagatatgca gaaggtaaaa ttatggttgg
     8281 ttaagttacc aaggagtaat ataaatttat aatggattta gagtagcact gtaaatctgt
     8341 tgataaaata aatgagccta gatgtaatta tatgaagaaa taaaatcaac taataaacaa
     8401 aattaattaa tgaaataaaa aaacagggaa ataaaataca aataaaaagg taaatcaaaa
     8461 ttaaattaat ctgtgtatat aaaattatat attgtgtata agttttgtat gtgtaaagta
     8521 tataagtttt gtatgtgtaa acaattaatt taagagatat tatataaatt gtgtattagg
     8581 gaggaagttt cgagatgaag caatatatag tcattgggtg tgggagattt ggaagttcag
     8641 ttgcgtctac tatgcatctt ttaggacatc aagtaatggc aatagacaaa aatgaagatt
     8701 cagttcaaag tatatctgac aaggtaaccc attcacttat agtggatgtt actgatgagc
     8761 aagcgttaag gtcattaggt ttaggtaact ttgatgtagc agtagttgca ataggttctg
     8821 atataagggc atctataatg gcgactctta tagccaaaga aatgggtgta gagttgataa
     8881 tatgtaaggc aaaggatgaa ttacaagcta aagtgcttta taaaattggc gcagatagag
     8941 ttgtatttcc agaaagagat atgggagtaa gagttgcaca caatttagtt tcggataata
     9001 tattagacca tattgaactt gacccagagt attcaattgt tgaaatcgta actccaaata
     9061 gttgggttgg caagacactt atagagcttg aattaagagc tagatatgag ataactgtac
     9121 ttgctataaa aacaggtaaa aatataaatg ttacaccttc tccagatgag gaacttacag
     9181 ccggaagtat cctagttata atcggtcaaa atactagtat aacagcgata acatctggaa
     9241 ataaggggat aattagaaga agataattta ctatttaata tatatttaat tgcaatgaaa
     9301 gtaaagagta tcatataatt atgaatagtt atatgatact atttttattt aatcgaaggt
     9361 agtatttatt tgtaagatta gataaagaga agttaaatta aaagtaagga ggctgtgcta
     9421 atataaaaat ttataagtta ttagcattta gataaaatga ttacaaatat aaacagtaag
     9481 gataatgaaa agttaaagta tacaagagca ctattaaaat caaagaatag gaataaagag
     9541 tcaaagttca taatagaagg atacagaata gtaatgcttg cacttgaatg tatggcaaac
     9601 cttgattatg tatttatcaa tgaagaattt gaaaataaga aagaacatgt aaaactatta
     9661 gaagatttgg ataaaaaaaa cacaaagata tacaagacta ctaataaaaa ctttaaagaa
     9721 ttagtggata cagaaaatac tcaaggaata ataggtgtag tttcatttaa gaaaaaaaaa
     9781 ttaagtgaaa gtataaataa aaaagataaa tttgtattga ttttagatag aatacaagac
     9841 ccaggaaata tggggactat aataaggact gctgattctg ctggagtaga tgccataata
     9901 gcactaaagg gatgtgtcga tatatacaac ccaaaagtaa ttaggtctac tatgggttct
     9961 atttttgata tgaatataat tgatgcttca caagatgaaa ctgtggacat gcttaaatca
    10021 ttggatttta atatagtttc aagttactta aatacagaaa atttttatga caaaatagat
    10081 tatggttcaa aagtagcatt ggtgatagga aacgaagcaa atggaataaa tgaagaactt
    10141 gtatcaaagt ctgatatttt ggttaagata cctatatatg gtaaagccga gtcgttaaat
    10201 gctgcgataa gctctgctat actgatgtat gaaataaaaa aatacttaat ttaatgtatt
    10261 gtaataaata taatgtcatg ttataatctt gaattaaata gtagagtatc aaaaatagtc
    10321 aatatatatt aa
//
LOCUS       DAMJYN010000108        10171 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.113, whole genome shotgun sequence.
ACCESSION   DAMJYN010000108 DAMJYN010000000
VERSION     DAMJYN010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10171)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10171)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10171
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.113"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(77..265)
                     /locus_tag="PC466_003224"
     CDS             complement(77..265)
                     /locus_tag="PC466_003224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770581.1"
                     /translation="MNYHTKEELMEVLRVASSRIINCEKVQKKFSEETSHHTRFKNII
                     EAMYISKSLIMDEISKRD"
     gene            600..1568
                     /locus_tag="PC466_003225"
     CDS             600..1568
                     /locus_tag="PC466_003225"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HDF2770582.1"
                     /translation="MAIKPRKISIVGSGHVGSHCGFSLITQGVCDELFMIDIDESKSK
                     AQALDLADAVSYLPHKVHIEKGTFSDCKDSDIVVISVADSSEGPLRRQNTTRLDLLRP
                     TIGMIKSIVKPIVDSGFDGIFVVISNPVDVVTNYIWEKSGFPKNKVIGTGTALDSTKL
                     RRILSEETGIAQQSIQAYSMGEHGDSQMVPWSHVSIGGKPILDMIKDNPNTYSNLDLP
                     SIVEKNKKTGISIINGKDCTEFGIGTALVEIVKAILHNEKKVLPVSTLLEGQYNERNV
                     FAGVPCVIGKDGIEEIIEINMTEYEQNEFNKSCSVLRECIALSKTL"
     gene            complement(1685..2815)
                     /locus_tag="PC466_003226"
     CDS             complement(1685..2815)
                     /locus_tag="PC466_003226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2770583.1"
                     /translation="MNLKDFNGKRLKSARIFRAKTIEQLSKETKINKKDLKAFEENKY
                     VPNIENTLKLSNILNFPKEYFYKNENINIVVEDSHFNPQSKLPRVEEISYREKIIIIH
                     KIYSFMENYIKFPKENLPNRKVMSDINISDIESLAYKTREFWDLNSTPIVNMVSLLES
                     KGIIISGMNVDRKGATIFTQKQRISKESKYLISLGNDKKSASIRNYTLACELGYIISS
                     ELRIPSKQFSEDEYACAFLLPKESFLKDLTHPEDLDYYVELKKKWIVPISAMIFRAYN
                     LEKINYKKYNYLMNEMDKKGWLIEEPLDKMKGSSPTYLKRAVELLIENKIMSVNSIVS
                     SLEEFGINLYPEDLELLMGLKKGLLSQEVNKKSKVIKFDGKK"
     gene            complement(2968..3921)
                     /gene="msrA"
                     /locus_tag="PC466_003227"
     CDS             complement(2968..3921)
                     /gene="msrA"
                     /locus_tag="PC466_003227"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HDF2770584.1"
                     /translation="MIKLATFAGGCFWCMVKPFDKYDGVIKVVSGYTGGHVENPTYQE
                     VCSGTTGHLEAIQITYDDDIISYDELLNIFWKQINPTDDGGQFGDRGTQYKTAIFYHD
                     EEQKNIALESREHLENSKIFDSKIVTDIIPATKFYEAEENHQDYYKKRPLNYNMYYKG
                     SGRYNFVKSHWDGNNINREELKKTLTPIQFEVTQNDMTEVPFENEYYDNNKEGIYVDI
                     VSGEVLFSSKDKFDSGCGWPSFSKPVIDKSIIERSDFSQGMYRIEVRSAKGNSHLGHV
                     FDDGPKELGGLRYCINSASLKFIPRENMEVLGYGEYLKLFE"
     gene            complement(4045..4950)
                     /locus_tag="PC466_003228"
     CDS             complement(4045..4950)
                     /locus_tag="PC466_003228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HDF2770585.1"
                     /translation="MKSSNFNILAFDGGGLKGALSISILERIVKEYPNLLNNINMFGG
                     TSTGSLIALGLAYGVSPKEIKELYSIENSKYIFNKSYAEILRPKYENKNLKEVLLSIF
                     PEELELKDLNKLVMIPSFYIGNEENAWKPVFYNNMPNSFTKTSKVVDVAMASSAAPVF
                     FPTYNRHVDGGIIATDPSLACIIHAIDSGFKLKNTRLFSIGTGYVYNSIKADTTEWGA
                     IDWIINKEPDLPIISITLEGNSQMSQLFSQKLLGDNYYRLNPKMEKDVAMDDCDALEY
                     LMSLGENCDIKDAFGWIKKKSFYRN"
     gene            complement(5314..6906)
                     /gene="hcp"
                     /locus_tag="PC466_003229"
                     /gene_synonym="priS"
     CDS             complement(5314..6906)
                     /gene="hcp"
                     /locus_tag="PC466_003229"
                     /gene_synonym="priS"
                     /EC_number="1.7.99.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxylamine reductase"
                     /protein_id="HDF2770586.1"
                     /translation="MEKMFCFQCEQTAGGKGCTINGVCGKKGGTANLQDELTGVLIGL
                     SRATIGNKNRPTSETDKIMIEGLFTTITNVSFDDEAIKRQIEKTEVEKSKLVPRCSDC
                     STTCNRNDNYDMKDLWNDNEDIRSLKSLILFGLRGMAAYAYHAMVLGYTDKDVNEFFY
                     EGLIAVGGDLSIDELLGLVMKTGEINLKCMELLDRANTETYGTPEPTQVSMKIEKGPF
                     IVVTGHDLYDLHKLLEQTKDKGINIYTHGELLPAHAYPKLKEYKHLKGNFGTAWQNQQ
                     KEFDNIPAPILFTTNCLMPVKDSYRDRVFTTEVVAYPGMVHIDEDKDFSSVIEKALEL
                     GGYREDVHMTGINGGDTLTTGFARGTVSSVQDKVVDAVKSGAIRHFLLVGGCDGAKLG
                     RNYYTEFVKQAPKDTVILTLACGKYRFNDLDLGDIGGLPRLMDMGQCNDAYSAIKVAV
                     SLANAFECGVNDLPLSMVLSWYEQKAVCILLTLLHLGIKNIYIGPSLPAFLSKNVLDI
                     LVDKFALTPISTPEEDMKKILG"
     gene            complement(6966..7691)
                     /locus_tag="PC466_003230"
     CDS             complement(6966..7691)
                     /locus_tag="PC466_003230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDF2770587.1"
                     /translation="MMRKIIKIDEGKCNGCGLCVEACHEEAIGMVNGKAKLLRDDYCD
                     GLGDCLPTCPTNAISFEYREAAEYDEAAVKANMEAKKAQKKTLACGCPGSQSKSINRE
                     VSNSTSISNDIVEIKGSQLNQWPVQIKLVPTNASYLKNASLLIAADCTAYAYGNFHNK
                     FMKNKVTLIGCPKLDEVDYAEKLTEILKENDIKNIVVTRMEVPCCGGIVNAVKTALQN
                     SGKMIPWQIVTISVDGKIVDGEI"
     gene            7832..8560
                     /locus_tag="PC466_003231"
     CDS             7832..8560
                     /locus_tag="PC466_003231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HDF2770588.1"
                     /translation="MKTNYRLHMQQGSDYLKKFLEKHIDLLKKIPLFEGIKSDELEEM
                     LECLGVVDKTYPKDSIIFSVGSEVTSIGIMLKGSAHIIKEDIEGNRNIVAELLPGDLF
                     GEVFACTRLHKSNVTVTTTSSCEVLFIKFKSVTGICSSACVFHNRLVENMLQLIAEKN
                     ILLHNKIELLSRKTTREKLLMYFSKQIEQTGSHQFTIPFSRNEMADFLCVDRSSMSRE
                     LGKMRDEGLLSFNKNKFEIFYFQK"
     gene            complement(8724..9995)
                     /locus_tag="PC466_003232"
                     /pseudo
     CDS             complement(8724..9995)
                     /locus_tag="PC466_003232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017416360.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="dicarboxylate/amino acid:cation symporter"
BASE COUNT         3385 a         1724 c         1169 g         3893 t
ORIGIN      
        1 tttataacaa gtatgcttac ttattttctt atataataaa atgtatatta aaacatatta
       61 aattgcaaaa taagcttcaa tctcttttac taatttcatc cattattaat gattttgaaa
      121 tatacattgc ttctataata ttcttaaaac gtgtatgatg agatgtctcc tcagaaaatt
      181 tcttctgtac tttttcacaa ttaataatcc ttgaagatgc tactctcagt acttccatca
      241 actcttcttt tgtatgataa ttcataacac atttactcct ttgtttttta atttagagaa
      301 acagtatacc tcaatttaat atcattatca actgatatca ttattattta tatatatctt
      361 ttaacactta aatattctaa ctatcagtga cattacatat tttaataatt attaatatac
      421 atataatact ttaacattca ttaatagaga gtatattaac attgcttttt taaaaatttt
      481 agtataaaat catattaaat aaattttctg aaataataaa atattaaaat atccaaaaac
      541 agcttttgat aacatctata attttcaatg tatcgttatt ttagggggag tgatttaaaa
      601 tggcaataaa gccaagaaaa atatctattg taggttcagg gcatgttggt tctcattgtg
      661 gatttagttt aataactcaa ggagtttgtg atgaactctt tatgattgat atagatgaat
      721 ctaaatcaaa agctcaagct ttagatttag ctgatgcagt ttcatatcta ccacataaag
      781 tacatataga aaaaggaact ttttctgact gtaaagattc tgacatagta gtgataagtg
      841 ttgcagactc ttcagaaggg cctttacgta gacaaaacac aactagatta gatttactaa
      901 gaccaactat tggaatgata aaatctatag taaaacccat agttgattct ggctttgatg
      961 gtatatttgt agtcatatct aatcctgttg atgtagttac aaattatatt tgggaaaaat
     1021 ctggctttcc taaaaataaa gtcattggaa ctggaacagc tttagattca acaaaactta
     1081 gaaggatttt atctgaagaa actggaatcg ctcaacaatc aattcaagct tattctatgg
     1141 gtgaacatgg agattctcaa atggttcctt ggtctcatgt ttcaattggt ggtaaaccaa
     1201 tcttggacat gataaaagac aacccaaata cttatagcaa tttagactta ccatcaatag
     1261 ttgaaaaaaa taaaaaaaca gggataagta taataaatgg taaagattgt acagaatttg
     1321 gtataggtac tgctttagta gaaattgtaa aagctatact acacaatgag aaaaaagttc
     1381 ttccagtttc tacattacta gaaggtcaat ataacgaaag aaatgtattt gcaggtgttc
     1441 catgtgttat aggaaaagat ggtattgaag aaattattga aatcaatatg actgaatatg
     1501 agcaaaacga atttaataaa tcttgctctg ttttaagaga atgtattgca ctttcaaaaa
     1561 cactttagat tcaatattct ttcttacact aaaagcaggt aaatgactta ttgaaaagac
     1621 ttttaactaa gttaatgttt aaatcattta tacctgcttt taattttaat actaaaatat
     1681 aaacctattt tttaccatca aattttataa ctttactttt tttatttacc tcttgagata
     1741 acaatccttt tttcaatccc atcaataatt ctaagtcttc tggataaaga tttattccaa
     1801 attcctctaa acttgatact atactattta cactcattat tttattttct atcaataatt
     1861 caactgctct ttttaaatac gttgggcttg aacctttcat tttgtctagt ggttcttcta
     1921 tcaaccagcc ttttttatcc atttcattca taagataatt gtattttttg taatttatct
     1981 tttctagatt atatgctcta aaaatcatag cagatatagg tacaatccat tttttcttta
     2041 gttctacata ataatctaaa tcttctggat gagtcaaatc ttttaaaaaa ctctcttttg
     2101 gcaataaaaa tgcacaggca tactcatctt ctgaaaattg cttacttggt attcttaatt
     2161 cacttgatat tatatatcca agctcacatg ccaaagtata atttctaatt gatgctgact
     2221 ttttgtcatt acccagagat attagatatt tagattcttt actaattctc tgtttttgag
     2281 taaagatagt tgcccctttt ctatctacat tcatacctga tattataatc cctttagatt
     2341 ctaacaaact taccatattt actattggag tactatttaa atcccaaaac tctctagtct
     2401 tatatgcaag agattctata tcacttatat taatatctga cattactttt ctatttggca
     2461 agttttcttt tggaaactta atataattct ccataaatga atatatttta tgtattataa
     2521 ttattttttc tctataagaa atctcttcta ctctaggtag tttagattga gggttaaaat
     2581 ggctatcctc tacaacgata tttatatttt catttttata aaaatactct tttggaaaat
     2641 ttaatatatt agataatttt aatgtatttt ctatatttgg tacatactta ttttcctcaa
     2701 aagcttttaa atctttttta tttattttag tttctttaga caactgttct atcgtctttg
     2761 ctctaaaaat tctagctgat tttaatctct ttccattaaa gtcttttaaa ttcatttgtt
     2821 ttctctcttt caaaattaaa ttcttaatct attggtataa ataagattac aattaataat
     2881 ttatcatatt attgacaaaa aaacaaaagg tgaaaatatt tttttatatt ttcacctttt
     2941 agataagttt ataataaata ttcctaatta ctcaaaaagt tttaaatatt ctccatatcc
     3001 taaaacttcc atattttctc ttggtataaa tttaagagaa gcagaattta tacaatatct
     3061 taaacctcca agttcttttg gaccatcatc aaatacatga cctaaatgag aatttccttt
     3121 agcacttctt acttcaattc tgtacatacc ttgtgagaaa tcacttctct caatgataga
     3181 tttatctata actggctttg aaaaacttgg ccacccacat ccagaatcaa atttatcttt
     3241 tgaagaaaat aacacttctc cacttacaat atcaacataa attccctctt tgttattatc
     3301 ataatattca ttttcaaaag gtacttctgt catatcattt tgagtgactt caaattgtat
     3361 aggagttaaa gtctttttta actcttccct atttatattg tttccatccc aatgactttt
     3421 tacaaaatta tatcttccag accctttata atacatattg tagtttaatg gtcttttttt
     3481 ataataatcc tgatgatttt cttctgcttc gtagaattta gttgctggaa ttatatcagt
     3541 cactatttta ctatcaaata ttttactatt ttccagatgt tctcttgact ctaaagctat
     3601 atttttttgt tcttcatcat gataaaatat agcagtctta tattgagttc ccctatcacc
     3661 aaattgtcca ccatcatctg taggattaat ctgtttccag aagatattta gaagttcatc
     3721 ataacttatt atatcatcat catatgttat ttgaattgct tctaaatgac cagtagttcc
     3781 tgaacatacc tcttgatatg tagggttttc aacatgacca cctgtatatc cagaaactac
     3841 tttaataact ccatcatact tatcgaaagg ttttaccata caccaaaaac atccacctgc
     3901 aaaagtagca agttttatca ttttcatcac tccttaaata aattatactt tatttattcc
     3961 ctaagaagta acttaataat ctgcatttta ttatttttac ctactcaatg aaatcatgtg
     4021 caaaaataca attgcaaatt gaatctaatt tctataaaag ctctttttct ttatccatcc
     4081 aaaagcatct tttatatcac aattttctcc taaagacatt agatattcta atgcatcaca
     4141 atcatccata gctacatctt tttccatctt aggatttaat ctatagtaat tatctccaag
     4201 aagtttttga gaaaataact gactcatttg agaatttcct tctaaggtaa tagatataat
     4261 tggtaaatcg ggttctttat taattatcca gtcaatagct ccccattcag tagtatctgc
     4321 ctttatacta ttatatacat atccagtccc tattgaaaaa agtcttgtat tcttaagttt
     4381 aaatccactg tcaatggcat gaattataca cgctaaactt gggtcagttg ctattattcc
     4441 tccatcaaca tgacgattat atgttggaaa aaatactgga gcagcactac ttgccattgc
     4501 tacatctaca actttgctag tctttgtaaa agaatttggc atattgttat aaaacactgg
     4561 tttccatgca ttttcctcat ttcctatata aaaacttggt atcattacta atttatttaa
     4621 atcttttaat tctagttcct ctggaaatat acttaataaa acttctttta agtttttgtt
     4681 ttcatacttt ggtctgagta tttctgcata acttttatta aaaatatact tagaattttc
     4741 aattgagtaa agttctttta tctctttagg gcttacacca tacgcaagtc ctagtgcaat
     4801 tagactccct gtagatgtcc ctccaaacat atttatattg tttaatagat ttggatactc
     4861 ttttactatc ctctcaagta tggatatact caatgcccct tttaatccac caccatcaaa
     4921 tgccaatata ttaaaattag aacttttcat atacatatac ccccacataa aacaccttat
     4981 attttaatca aaataatttc actatagtat atatatttta tgcaagttac atattacaat
     5041 gttcctcttt taatatttaa gttacattca aacctttagt acttaaaata aaatatataa
     5101 gatattatat atctaagtat tataaattta atacaaaaat tcttaaaaga atatactgaa
     5161 agcaggttta tttttcaatt attacaaaaa ataaataaag ggtcgtctca aaattgattt
     5221 tttaatcaaa ttttaagttt aaccccttat cttaattgtg acatacttaa aaatatttta
     5281 actataaata tctttaagta tagatatatt tatttatcct aaaatcttct tcatatcttc
     5341 ttcaggagta gatataggtg tcaatgcaaa tttatcaacc aatatatcta atacattctt
     5401 agataagaat gctggcaaag aaggccctat atagatattt ttgataccta aatgaagtag
     5461 tgtaagaagt atacaaacag ctttctgctc ataccatgac agtaccatgc taagaggcaa
     5521 atcatttact ccacattcaa aagcatttgc caatgaaact gccactttaa ttgcactata
     5581 agcatcatta cattgtccca tatccattaa acgaggtaag ccacctatat ccccaaggtc
     5641 taaatcatta aatctatatt ttccacatgc aagtgtcaat ataacagtat ctttaggagc
     5701 ttgttttaca aattcagtgt aataatttct tccaagtttt gcaccatcac aacctccaac
     5761 caataaaaag tgtcttatag ctccactctt tacagcatct actactttat cttgtacaga
     5821 tgaaactgta cctcttgcaa aaccagtagt taatgtatct cctccattaa taccagtcat
     5881 atgaacatct tctctatatc ctccaagttc aagagctttt tctattacac tagaaaaatc
     5941 tttatcttca tcaatatgaa ccatacctgg ataagcaact acttctgtag taaatactct
     6001 atctctataa ctatctttaa caggcattaa acagtttgtt gtaaataata ttggagcagg
     6061 aatattatca aattcttttt gttggttttg ccatgctgta ccaaaattac cttttagatg
     6121 tttatattct tttagttttg gatatgcatg tgctggtaat aactcaccat gagtatatat
     6181 atttataccc ttatctttcg tttgttctaa taatttgtgt aaatcataaa ggtcatgtcc
     6241 tgtaactaca ataaatggcc ctttctcgat tttcatagat acctgagtcg gttctggtgt
     6301 tccataagtt tcagtatttg ctctatcaag caattccata cattttaagt ttatttctcc
     6361 agttttcata actagaccta aaagttcgtc aatagacaag tctcctccaa ctgctattaa
     6421 tccttcatag aaaaattcat ttacgtcttt gtctgtataa ccaagtacca ttgcatgata
     6481 tgcataggca gccatgcctc ttaatccaaa taagattaat gattttaatg aacgtatatc
     6541 ctcattatca ttccataaat ccttcatatc atagttatca tttctattac aagttgttga
     6601 acaatctgaa catctaggta caagtttact tttttctacc tcagtttttt caatttgtct
     6661 ttttatagct tcatcatcaa aacttacatt cgttatagta gtgaatagcc cctctatcat
     6721 aattttatct gtttcacttg ttggtctatt cttatttcca atagttgctc ttgaaagacc
     6781 aatcaacact cctgtaagct cgtcttgcaa gttagctgta cccccctttt taccacaaac
     6841 accatttata gtacaacctt tacctcctgc tgtttgttca cattgaaaac aaaacatttt
     6901 ttccattttt tattcctccc tttttattta ttaaaattta ttatattttt ctatgattca
     6961 cttaattaaa tttctccatc tacaattttt ccatctacag atatagtaac tatttgccat
     7021 ggtatcattt ttccactatt ttgtagagct gtcttaacag catttactat accaccacag
     7081 caaggaactt ccatacgtgt tactactata tttttaatat cattttcttt taaaatctct
     7141 gtcagttttt cagcatagtc aacttcatca agtttagggc atccgattaa tgtaacctta
     7201 tttttcataa atttattatg aaaatttcca tatgcatacg ctgtacagtc tgctgctatt
     7261 aaaagacttg cattctttaa atatgatgca ttagttggta ctaattttat ttgtactggc
     7321 cattgattaa gttgagaacc ttttatctct actatatcat tgcttataga tgtactattt
     7381 gaaacctctc tatttattga cttagactga gaacctggac atccacatgc taaagttttc
     7441 ttttgtgctt tctttgcttc catatttgct tttactgcag cttcatcata ttctgctgct
     7501 tctctatact caaatgaaat cgcatttgtt ggacaagttg gcagacaatc tcccagccca
     7561 tcacaatagt catctcttaa aagttttgct tttccattta ccattcctat agcttcttca
     7621 tgacaagctt caacacatag tccacaacca ttacactttc cctcatcaat tttaattatt
     7681 tttctcatca tttatatcac ctcataaaat ttttttaatt taaagtattg atttcttata
     7741 tatttatttt taatacctat atttctttat ttcaaatttc ttgtagtagg atttttatat
     7801 ccccttgctt ttataaactt agtatagtac aatgaaaaca aattatcggt tgcatatgca
     7861 acaaggaagt gattatttga aaaaattttt agaaaagcat atagacctac ttaaaaaaat
     7921 tcctctattt gaaggaatta aaagtgatga gcttgaagaa atgttggaat gtttaggtgt
     7981 tgtagataag acttacccaa aagatagtat aatattctct gttggaagtg aagttacttc
     8041 tattggaatt atgcttaaag gaagtgctca tataataaag gaagatatcg aagggaatag
     8101 gaatattgta gctgaactct tgcctggaga tttatttgga gaggtattcg catgtactag
     8161 actacataaa agtaatgtta cagtaaccac aacatcttct tgcgaagttt tatttataaa
     8221 gtttaaaagt gtaactggta tttgttcatc tgcatgtgta tttcataata ggcttgttga
     8281 aaatatgcta caattaatag ctgaaaaaaa cattttactt cacaataaaa tagaattact
     8341 ttctcgtaaa acaactcgcg agaaattgct tatgtatttt tcaaaacaga tagaacaaac
     8401 aggtagccac cagtttacaa ttcccttttc aagaaatgaa atggctgatt ttttatgtgt
     8461 tgacagaagt tctatgtcaa gagagcttgg caagatgcga gatgaaggct tgttatcttt
     8521 taataaaaat aaatttgaaa tcttttactt tcaaaaataa actagatatt taaacatatt
     8581 tatttcaata tatactatat tagttaattc aaattataaa tatcatattt gaatcttaaa
     8641 tttatatttt tacttaaaaa gttaatagat atctaattta ttaaaattaa gatacctatt
     8701 aactttatta attaagtgta caattagctt attttctttg tagtaattgc tgttttatct
     8761 ataagccaat cttttccttc tactaatctt gaaactaaca ttgatgatac tgtatttcca
     8821 gttgtattta atatagtatt aggaatatca gttatagtag ttataactgt taacaatgga
     8881 attgcctcca ctggaaaacc gaagatgcta accacgagca tctcaccaat aagtcagcca
     8941 cctgctacag gagccataaa tactccaaca acaaatacag ttataaataa ttgacctatc
     9001 gttgctggat ttgccattcc actgcctaaa atacctgata aaaatgccac ttttattatt
     9061 actgctaaaa ctgacccatc tttatgtata tttattccaa gaggtataac tgtttctgat
     9121 atatcatcag gaactcctat atttttacta gcttctaaat ttgatggtat acatgctgaa
     9181 cttgaagaag tagctagtgc cgttgctatt ggttttatag catttctcca gaattgtcta
     9241 aacccttgtt ttcctgcaga taaaaaagca tacagactgt aaaataataa gaaatacatg
     9301 gctgctgtta gtgaataaat tacaaacacc cttacatatc cttgaattat tttgcttcca
     9361 agttccccaa ttattgtagc tgtataacag cctagcccta taggagcata aagcatgact
     9421 atacttacta cttttaatat tgcttccgtt ccttctgata aaaactttct tattgtattt
     9481 cccctatctc ccatcatagc tattgctgtt ccaactaaaa ctgcaaatat aactaattgt
     9541 agtaaattgc tactggaaaa taaatctcca aaatttttaa ctgtaatact tgatactact
     9601 tggtctaata acgttccttt tgattctaaa gtttctgcat cttgagccac cattaaactt
     9661 tttacacttg atacatctaa tcctttagac ggattaaata ataatgcaga tgtaatacct
     9721 aaaaatgcaa ttacaagtgt tgttcccata aatactatag ctgtactctt cattattttt
     9781 ccaaaacgtt ccatattttt tatactagca acacctgaag aaacactaag aaaaactaat
     9841 ggtactacta tcattaatag agcatttatg aataaatctc caaatggttt tagtattgaa
     9901 gcttttggac caagtactaa tcctactatc acccctatta tagtacatgc taaaagtata
     9961 attgatgact tataattttt taaaaagtcc ctcatttata ttttcctttc taatgtttta
    10021 tattataaat taccctaaat cctaaaaaaa ttaaagtaaa ttatctaatg cgcattaata
    10081 atttttgtaa ttttccccaa cagctacttt agcaaatact ggaatatatg tcaatttcta
    10141 tagttttttt gtatctttaa tattttatta a
//
LOCUS       DAMJYN010000109        10131 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.114, whole genome shotgun sequence.
ACCESSION   DAMJYN010000109 DAMJYN010000000
VERSION     DAMJYN010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10131)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10131)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10131
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.114"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(100..1980)
                     /locus_tag="PC466_003233"
     CDS             complement(100..1980)
                     /locus_tag="PC466_003233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp10"
                     /protein_id="HDF2770589.1"
                     /translation="MSKRKSFIRTIAVSTMAVAVTGSVTCAYAAPVLQGTKTYEKVNT
                     IDISVDSVENIVYSFQASIKVQGEVEVVDNEQKEKITWSDNIKSQIKSGNANATCRVE
                     YNKSSNTTTLDIYVTSNEDLLDGNRLNIGRISVKKSGSNSNADYKVLGKGTSDKPALK
                     IVTYNNKTVDYENINSDEGLIFTLINESEVKPIGGTGSSKNDPEKYKVEKSEALEYLL
                     NNIRINYSIVSKETQESGSNVILKLGLAQKITKGRKATINKYVEVTLPKSLEYIVENE
                     LSKPDELPPDNGNGGNNGGGSNSGGSSSGGSSGGGSSSNSTSNVTVKKLKGADRFETA
                     TKISQSGWTKSDTVVIVNGEDKSMVDGLTATPLASVKNSPILLSSNEKLPQKTVEELK
                     RLNPSKVIVIGGNNSMPNSVVEAIKAVNSKISVQRIGGDTRYQTSINIAKEIDKTNNV
                     SKLYIGAGNGEADSLSIASLAGKEKTPIVLTQKDGVDNEAVQFIKSNKVSNIYFIGGI
                     EKISNKAIEQVGKIANKDISNNRVAGQTRQETNAKVIDKFYSQSKLDGVVVANQDKLI
                     DALAVGPLAAKNNSPVILATNTLDKSQESSLKGKNSSKLFEVGGGIASSVVDKIKSLI
                     EK"
     gene            complement(2190..8153)
                     /locus_tag="PC466_003234"
     CDS             complement(2190..8153)
                     /locus_tag="PC466_003234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin type III domain-containing protein"
                     /protein_id="HDF2770590.1"
                     /translation="MKKAISCVLAVSMCSAPLNVFAEPILEGKLRAVEKSVTEKLRGN
                     LEVDLNFSLPIKNSESESMTNMQLRLKDDSNNSGIIKLGEKDSGTVNIGTDNIEYTIK
                     KLSASRSEIKNKDENVSYYNIVFNNLPVGKYNIEVSGAGFKNKEIKDIDISSYSQRVL
                     LSNRASVDNKNKPLNYELFLMGDVNGDGKVDKSDYNKVLENIDSNKREFDLNRDGKVD
                     IVDLDYVQKNLGQSEDAKSLESIVSTNPIVDTSKVELKGNSDVDINGNVENLFSGENN
                     GVTISSKNDEISEEKPAVMDIALSEALNMEVINIKAPEGTAPAKGIVEVTDEDGNVQQ
                     IPYENKEYMKNLKDKEQQEEVNNEQEEVNQEEVNNKDENKNQTDNNSNNKDENNDKQQ
                     ENSDKQEVNSNTNQDKNNDKENSSMDKPNSDEDTPKEGDNISKDDNSTTSTYSRAALE
                     TYTDVQNSDIVINLGKQVAVKKITIKITATTANDRNLAEISKVEFLNNVYKEIPKPEM
                     NIPKINKISTSTAVGNEKVSFYWNNEVNVSAYELILDKIDSKGKVLSTKKLQTSKNTI
                     EVRDIEAYGLYRVSIQSLNGDWSSGYKDATPENLDGVPENVDSNYKPIQFSPDSILEF
                     QVVPDTKPEPPEGINVKGKFKSLDVSWKNHKQAKDFDLYYKEKGSNGSWIKYNDKLIR
                     GTSLKIEGLKDNTTYEVRMTATNHLGTSGMSKTYIGTTESIDAPTTPNYRLINTPKEN
                     GGFGIPTNHIVDVVYPAGYDKSEYSDKNPFDKFNVVDGDFTTHWTFPTYNAAEGTNRG
                     PIITFDKSYTMDTFMATPRFDVSDKTINDFEIRYWDENGQLHNLGDVPFETKTDPVNN
                     NKYVMVRLKEPITATKIQVSVCSSYSYKSNISELKFYEYDSIEDDVRNLFMDDLQVEL
                     KEDVTQEKITELKDRLNTPDKASGEYHPYKTVIDRELKLAQDLYNDRATLTDVTTVNQ
                     EINKSGKYKDKNGQYTVNSNNLGMQNDWQALGVAARAGDEITVYVGSKSGKTPKLIYT
                     QYYGESGAYKSGEINLKTGKNVIQLSKLHSLDIECGGSLYIRYPEDTPSGGDIKVRVA
                     GATKIPHLNLNGTINDKSPAGVSESKKKIKAYIEELAKYKDAVKGEPYYPGTNIGNSY
                     EYSEKTGVLNTTDIESDKVTLNVPATAVYQGISKGNADLNTQVDRLYNSMLAWEQIMD
                     LVYSERGVFKTQDLDGNGTVDDNEFNLTKNDMAPKSRMNIKYQRMFIGAFMYASGLHV
                     GVEYGSVPGLMNGVPFQIDDSGKATGGNLFGWGIGHEIGHVTDIGKMTYSETSNNVLA
                     LLAQTFDDKTHSRLEGSTMDKIYEHVTSNSLGIPSNVFERLGMLWQLHLAYDDDFTGS
                     MLKNNSDADLSNDTFYAKISRKYRALSSSDPINSLPKDQMLVAMASSVVEKDLRDYFK
                     AWGVEITPELNSIMDSKNYEKESRKIQYVNDEARRKILNENIASMAKDTKVSASFSDG
                     IQSGSLVKSNKISIDLDVDKDKDKILGYEIIRSDGNYLDGENGTQVKYRTVGFVDAKG
                     NSKAKFTDSISPLNNRAFTYKVVAYDYHLNPTEEFEVGTVKLSDEGKINKSAWSFITN
                     TVSDGDVRTENDSHGPLQNPEIDNIKDNDVSTTYKGKIISKAEWNKDPQKDPDINVEE
                     NPYIIVDMKETLPIVGLKYTKPEAETRKFSLKGLFNFRKNTSTTYNPLTNYKIQVSND
                     KKNWEDVSQGTFEYGQDLVGGGKDQDNEARVTFNKDDKLWTYQARYVKLISNNKSNIE
                     VAELDIIGPPGDNIEIGTMNNADQTRTNGIGKLAEDYVYQSDDPSTSEDETGKIPAGS
                     IIITGEYSGNPAFNLPLLIDKNNKTISGEALLFAEVPEKGELGEISKGTWVYYMPKEN
                     FDSLSDKVKAELYRYNDLQGDTPVGQRFVSDTMYVPVGAKNYDELKTISLTDSNSKAR
                     KATRNAIDVSNKKVITVSNKVKGNIVRDK"
     regulatory      complement(8277..8362)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            complement(8534..9937)
                     /locus_tag="PC466_003235"
     CDS             complement(8534..9937)
                     /locus_tag="PC466_003235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp9"
                     /protein_id="HDF2770591.1"
                     /translation="MKNSKKILAIGLTLFLVMVNTPMVNALTSVEQIKGNDRYETAAK
                     IADKQNYNTAILINSDNSLADGLSASGLAGALNAPILMTKQNQIPNTTMERLNKAKTV
                     YIIGSESTISKNVENQLLSKKKVVQRIFGENRFDTSIKIAEKIKEIKPIDKVIIANGF
                     TGEADAISASPVAARDGVPIILIDGNSVGFDTTGLKSYALGSSEIISDELVKSTNSIR
                     LGGTDRFETNKIVIQEFYKNSKEFYLSKGLQLTDALVASTIAKNAPVVLVENGSNKSI
                     LSGADKLTVLGGINQNVIKQCINQASPNQQGLYYNPNDRAFKERIKGKVYALTKQYRK
                     DNGVRALSVASRLEGLANDWSNLMANKKTLSHTINGKNSYSTFLKYLDWSEIKPGYIA
                     VQGENIIKYKISDKPVYTNRDADDIGNFIFNEWKTNPEEGTNMLHKGYEIMGFGIAIT
                     GDKNLYATHEFYGRYKE"
BASE COUNT         2782 a         1880 c         1152 g         4317 t
ORIGIN      
        1 atattattaa attgttaaga taatgaaaat aaaataagaa tgcatctaaa tatataactt
       61 tatatctaaa tacattctta ttttcgattt acttaatatt tatttttcaa ttaaactctt
      121 aatcttatct actacagatg aggctattcc tccacctact tcaaacaact ttgatgaatt
      181 tttacctttt aatgatgatt cttgtgattt atctaacgta tttgtagcaa gtataactgg
      241 tgaattgttt ttagctgcta atggtccaac tgctaaagca tctataagtt tatcttgatt
      301 tgcaactaca actccatcta gtttagattg agagtagaat ttatctatta ctttggcatt
      361 cgtctcttgt ctagtttgac ctgccaccct attgtttgat atatctttgt ttgctatttt
      421 tccaacttgt tcaatagcct tgttagatat tttttctatt ccaccaataa agtatatatt
      481 tgacacctta tttgatttaa taaattgtac agcttcatta tctacaccat ctttttgtgt
      541 aagtactatt ggagtttttt ctttaccggc cagtgatgct attgataatg aatctgcttc
      601 tccatttcct gcccctatat acaatttgct tacattattc gtcttatcta tttcttttgc
      661 tatattaata gaagtttgat atcttgtatc tccacctatt ctctgtactg atatttttga
      721 atttacagct ttgatagctt caacaactga atttggcatt gagttgtttc cacctatcac
      781 aattactttt gatggattta gccttttcaa ttcttctaca gttttttgag gaagcttttc
      841 atttgatgat aaaagaatcg gtgagttttt tacactagca agtggtgtag ctgtaagccc
      901 atccaccatg cttttatctt ctccatttac tattacaact gtatctgatt ttgtccaacc
      961 actttgagat attttggtag ctgtctcaaa tctatcagca ccttttaatt ttttgactgt
     1021 gacattagat gtagaattac ttgaacttcc tcctccagaa cttccaccac tagacgagcc
     1081 gcctgaatta cttccaccac cattatttcc accattgcca ttatctggtg gtaattcatc
     1141 cggttttgat aattcatttt caactatgta ttctaaactt tttggaagtg taacttcaac
     1201 atatttattt attgtagctt ttcttccctt agttattttt tgtgctaatc caagttttaa
     1261 tattacattt gaaccacttt cttgtgtttc tttactaaca atagaatagt ttatcctaat
     1321 attgtttaat aaatattcaa gtgcttcact tttctctacc ttatacttct cagggtcatt
     1381 tttactagaa ccagttccac caattggttt tacttcactc tcattaataa gggtaaatat
     1441 taatccttca tcagagttta tattttcata atccactgtt ttgttgttat atgttacaat
     1501 ttttaaagct ggtttatcgc ttgttccttt tcctaaaact ttatagtcag catttgagtt
     1561 actgccagat ttttttacag atattcttcc tatattcaat ctatttccgt ctagtaaatc
     1621 ttcatttgat gtaacatata tatctaatgt agttgtatta cttgatttgt tgtattctac
     1681 tctacaagta gcatttgcat ttccactttt tatctgagat tttatattat cagaccaagt
     1741 aatcttttct ttctgctcat tatctactac ttcaacctca ccttgtactt ttatactggc
     1801 ttgaaatgaa tatactatgt tttctactga gtccacagat atatctatag tatttacttt
     1861 ctcatacgtt tttgttcctt gtaaaactgg agctgcatat gcacatgtaa cactaccagt
     1921 tacagctact gccatagttg atactgctat agttcttata aaagattttc ttttactcat
     1981 taacacccgt ccttatctat cattaactaa gtggataaat ttacttatcc acctagcttt
     2041 tatatttaat ttataaatta ccctaaactt atagttacat ttatatactt tgcttttaat
     2101 atctactatt ttaaaactat tctagtacct aatcatatta gatatacaat gttagtatta
     2161 gtatttttac gtttttagag ttccacctac tatttatctc taacaatatt accctttact
     2221 ttattgctta cagttataac cttcttatta ctgacatcaa tagcatttct tgtagctttt
     2281 ctagctttac tattactatc agtaagactt attgtcttta actcatcata attcttagct
     2341 cctacaggta catacattgt atcacttaca aatctttgac ctactggcgt atctccttga
     2401 aggtcattgt atctatatag ttcagcctta accttatcac ttaaagaatc aaagttttct
     2461 tttggcatat agtaaaccca tgtaccttta ctgatttcac ctaattcacc tttttctgga
     2521 acttctgcaa ataaaagtgc ttctccagat atagtcttat tgtttttatc tataagtagt
     2581 ggtaaattaa atgctggatt tccactgtat tcacctgtaa taattattga acctgctgga
     2641 atcttacctg tttcatcttc acttgtgcta gggtcatcac tttgatatac ataatcttct
     2701 gctaactttc caattccatt agtacgagtt tggtctgcat tattcattgt gccaatttct
     2761 atattatcac ctggaggtcc tattatatct aattctgcaa cttctatatt agacttattg
     2821 tttgagatta gttttacata tctagcttgg tatgtccaaa gtttatcatc tttattaaat
     2881 gtaactctag cttcattatc ttggtctttt cctccaccaa ctaaatcttg tccatattca
     2941 aaagttcctt gacttacatc ttcccagttc tttttatcat tacttacttg tatcttgtaa
     3001 ttagttaaag gattgtatgt tgtgctagta ttctttctaa agttaaataa tccttttaat
     3061 gagaacttcc tagtttctgc ctctggtttt gtatatttta gtcctactat aggtaatgtt
     3121 tctttcatgt ctactattat atatggattt tcttctacat ttatatcagg gtctttttga
     3181 gggtctttgt tccactctgc tttacttatt atctttcctt tatatgtagt acttacatca
     3241 ttatctttta tattatcaat ttcaggattt tgtaatggtc catgtgagtc attttcagtt
     3301 ctaacatcac cgtcagaaac agtatttgtt atgaatgacc atgctgattt atttattttc
     3361 ccttcatctg ataattttac agtgccaact tcaaattctt ctgttggatt taggtgataa
     3421 tcatatgcaa ctaccttata tgtaaatgct ctgttattaa gaggagatat actatcagta
     3481 aatttggcct tactatttcc ttttgcatcc acaaatccaa ctgttctgta ttttacctgt
     3541 gttccatttt caccatctaa ataatttcca tcacttctta ttatttcgta tcctagtatc
     3601 ttatctttat ccttatctac atctaggtct atagatattt tattagattt aactagagaa
     3661 ccactttgta ttccatcaga aaaactagca cttactttag tatcttttgc catactagct
     3721 atattttcat ttaaaatctt tcttctagct tcgtcattta catattgtat ctttcttgat
     3781 tctttttcat agttcttact atccattata ctgtttaatt ctggtgtaat ttctactccc
     3841 catgccttaa agtaatctct taaatctttt tcaacaacac ttgatgccat tgctactagc
     3901 atttggtctt ttggtaaact attaattggg tcactacttg aaagtgctct gtattttctt
     3961 gaaatctttg catagaatgt atcattactt aaatcagcat ctgagttatt ctttaacatt
     4021 gaacccgtaa aatcatcatc ataagctaga tgtaattgcc ataacattcc aagcctttca
     4081 aatacattgc ttggtatacc taagctattt gaagttacat gctcatatat cttatccatt
     4141 gttgaacctt caagtcttga atgtgtctta tcatcaaagg tctgagcaag taaagcaagt
     4201 acattgttac tagtttcgct atatgtcatc tttccaatat ctgtaacatg tcctatttca
     4261 tgacctattc cccatccaaa taagtttcct cctgtagctt ttccactatc atctatttgg
     4321 aaaggtactc cattcataag ccctggaact gaaccatatt ctactcctac atgtaatcca
     4381 gaagcataca taaatgctcc aataaacatt ctttggtatt ttatgttcat acgagatttt
     4441 ggagccatat catttttagt taagttaaat tcattatcat ctacagttcc attaccatct
     4501 aaatcttgtg ttttaaatac tcctctttct gagtaaacta aatccattat ttgttcccat
     4561 gcaagcatac tattatataa tctatctact tgtgtattta aatcagcatt tccttttgat
     4621 attccttgat atacagctgt tgcaggaaca tttaatgtta ctttatcact ttcaatatct
     4681 gtagtgttta acacaccagt tttttctgaa tattcatatg aattaccaat atttgttcct
     4741 ggataatatg gttctccttt tacagcatct ttatatttag ctaattcttc tatatatgct
     4801 tttatctttt tcttagattc agaaactccc gcaggactct tatcatttat tgttccattt
     4861 agattaagat gtggtatctt agtagctcct gctacacgta cttttatatc tcctccactt
     4921 ggagtatctt cagggtatct tatgtataaa cttcctccac attctatatc taaactatga
     4981 agtttgctta attgaattac attttttcca gttttaagat ttatttctcc actcttatat
     5041 gcaccagatt ctccatagta ctgtgtatat atcaacttag gagtttttcc acttttactt
     5101 ccaacatata ctgttatttc atctcctgct ctagcagcta ctcctaatgc ctgccagtca
     5161 ttttgcatgc ctaagttatt ggaatttaca gtatactgtc cgtttttatc tttatatttt
     5221 cctgatttat ttatttcttg atttacagta gttacatcag taagtgtggc tctatcatta
     5281 tataagtctt gagctaattt taattctcta tcaataactg tcttatatgg atgatattct
     5341 ccactagctt tatctggagt atttaatcta tcttttaatt cagttatttt ttcttgagtt
     5401 acatcttctt ttaattcaac ttgtaggtca tccataaata gatttcttac atcatcttct
     5461 atactgtcat actcataaaa cttaagttct gatatattag acttatatga ataagatgaa
     5521 caaacactta cttgtatctt agtagcagtt attggttctt ttaatctaac cattacatac
     5581 ttattattat ttacagggtc tgtctttgtt tcaaaaggaa catcccccag attgtgtaat
     5641 tgaccatttt catcccaata tcgtatctca aagtcattta ttgtcttatc agaaacatca
     5701 aaacgaggtg tagccataaa agtatccata gtataagatt tatcaaaagt tattattggt
     5761 cctctattcg ttccctcagc tgcattatat gttgggaatg tccaatgtgt tgtgaagtct
     5821 ccatctacta cattgaattt atcaaatgga tttttatcac tatattcact tttgtcatat
     5881 cctgctggat aaacaacatc tacaatgtga tttgttggta ttccaaatcc accattctcc
     5941 ttaggagtat taattaatct atagttaggt gttgttggtg catctatgct ttcagttgta
     6001 cctatatatg ttttagacat tccactagtt cccaagtggt tagtagctgt cattctaact
     6061 tcatatgttg tgttatcctt aagaccttct atttttaaac ttgtcccacg aataagctta
     6121 tcattgtatt ttatccaaga cccattagag cctttttctt tatagtacaa gtcaaagtct
     6181 ttagcttgtt tatgattttt ccagcttaca tcaagagatt taaatttacc tttaacattt
     6241 ataccttctg gtggttctgg ttttgtgtct ggaacaactt gaaattctaa tatgctatct
     6301 gggctaaatt gtataggttt atagtttgag tctacatttt ctggtactcc atctaagttt
     6361 tctggcgttg catctttata accactagac caatctccat ttaaagattg tatgctaacc
     6421 ctatatagtc catatgcttc tatatctcta acttctattg tatttttact agtttgtaat
     6481 tttttagtag ataatacttt tcccttacta tcaattttat ctagtataag ttcgtatgct
     6541 gatacattta cttcattatt ccaataaaaa gatacttttt catttccaac agcagtgcta
     6601 gtcgatattt tatttatttt aggtatgttc atctctggct ttggtatttc tttatataca
     6661 ttgtttaaaa attcaacttt tgatatttct gcaagatttc tatcgtttgc tgttgtagct
     6721 gttattttta tagttatctt ttttactgct acttgtttac caagatttat tactatatcg
     6781 ctattttgaa catctgtata tgtttctaat gctgccctac tatatgtaga tgttgtagag
     6841 ttatcatctt tactgatatt atccccttct tttggagtat cttcatctga attaggttta
     6901 tccattgatg aattttcttt atcattattt ttatcttgat tggtattaga gtttacttct
     6961 tgtttatcgc tattttcctg ttgtttatca ttattttcat ctttattatt tgaattatta
     7021 tcagtctgat ttttattttc atctttatta tttacttctt cttgatttac ttcttcttgt
     7081 tcgttattta cttcctcttg ttgctcctta tcttttaagt ttttcatata ttctttattt
     7141 tcataaggaa tctgttgaac attaccatct tcgtcagtaa cctcaactat tccttttgct
     7201 ggagcagtac cttctggagc ttttatattg atgacttcca tattaagtgc ttctgataaa
     7261 gctatatcca ttactgctgg tttttcctca gatatttcat cattttttga agatattgta
     7321 actccattat tttctccact aaataaattt tctacattac cattaatatc tacatcacta
     7381 tttcctttta attcaacctt acttgtatct actataggat tggtagatac tatactttct
     7441 aggctttttg catcttcact ttgtcctaaa tttttctgta cataatctaa gtcaacaata
     7501 tctacctttc catctctatt taaatcaaat tctcttttat ttgaatctat attctctaaa
     7561 accttattat aatcactctt atctacttta ccgtctccat ttacatcacc cattaagaat
     7621 aattcataat ttaaaggttt atttttatta tctacacttg ctctattgct taataagact
     7681 ctttgtgaat aacttgatat atcaatgtct ttaatttctt tgttcttaaa tccagctcca
     7741 gagacttcta tattgtattt tccaacaggt aaattattaa atacaatatt ataatatgat
     7801 acattctcat ctttattttt tatttcactt ctacttgcag ataatttttt tatagtatat
     7861 tctatattat ctgtcccaat atttactgtt cctgaatctt tttctccaag ctttattatt
     7921 ccactattgt tactatcatc ttttaatcgt aactgcatat tagtcatact ttctgactcg
     7981 ctatttttta ttggcagtga aaaatttaaa tctacttcaa gattccccct taacttttct
     8041 gtaactgatt tttcaactgc ccttagcttc ccctctaata taggttctgc aaaaacattt
     8101 agtggtgcac tacacataga tactgctagt acacaagata ttgccttttt catgaaacaa
     8161 caatcctccc ttaataaatc tctaattttt catgaattta aatactataa gtttcagaca
     8221 ataaaaaaag acactcaaag agaatcttaa ttataaaata aaaagacttt actcttttta
     8281 gcaactggct gatatggctt taaaagcttt aatccctata gttttgcgtc attagatttc
     8341 cctaattttg ccatttaatt ttcactactt tcttacccat tttatactat atttaaactt
     8401 tttaatacaa tttttttaca ttaaattata aaaaaataac atttatatta ataaattaat
     8461 ataaatgtta ttttccatta taatttaatt atttatatag cttccttaca agcataattt
     8521 tgtgtatatt ttcttattct ttatatcttc cataaaattc atgtgtagca tatagattct
     8581 tatctcctgt tatagctata ccaaatccca ttatttcata ccctttatgc aacatattag
     8641 ttccttcttc tggatttgtc ttccactcat taaaaataaa gtttcctata tcatctgcat
     8701 ctctatttgt atatacaggt ttatctgaaa ttttatattt aattatattt tcaccttgaa
     8761 ctgctatata tccaggttta atctcactcc aatctaagta tttcaaaaaa gtagaatatg
     8821 aattttttcc atttatcgta tgagataaag tcttcttatt tgccattaaa ttagaccaat
     8881 catttgctag accctctaat ctgcttgcta cagataacgc tcttactcca ttatcttttc
     8941 tatactgctt tgtaagagca tatactttac cctttattct ctctttaaat gctctatcat
     9001 ttggattgta atataaccct tgttgatttg gtgaagcttg atttatacat tgcttgataa
     9061 cattctgatt tatgcctcct agtacagtca atttgtctgc accacttaaa atactcttgt
     9121 tactgccatt ttcaactaaa actacaggag cattttttgc tattgtagag gcgaccaaag
     9181 cgtctgttaa ttgcaagcct ttacttagat aaaattcttt actattttta taaaactctt
     9241 gtataactat cttattagtt tcaaatctat ctgtgccacc caatctaata gaatttgtgc
     9301 tcttaactaa ttcgtcgctg attatttcac tagaaccaag cgcataactc tttaagcctg
     9361 tcgtgtcaaa tcccacacta tttccatcta taagtattat aggtactcca tctctagcag
     9421 ctactggtga tgcacttatc gcatctgctt ctcctgtaaa tccattggct ataattactt
     9481 tatctattgg cttaatttct ttgatttttt cagctatttt tatacttgta tcaaatctat
     9541 tttcaccaaa tattctttgt acaaccttct ttttggataa taactgattc tcaacatttt
     9601 tacttattgt tgattctgag cctattatat acacagtctt tgctttgttt aatctttcca
     9661 tagttgtgtt tggaatctga ttttgctttg tcattaaaat aggcgcattt aaggctccag
     9721 ctaaaccact tgcacttaga ccatctgcta agctattatc tgagttgatt agtattgctg
     9781 tattgtagtt ttgcttatct gctatttttg ctgctgtctc atatctgtca ttccctttta
     9841 tttgctcaac tgatgtcaac gcatttacca taggagtatt taccattact aaaaatagtg
     9901 taagtcctat agctaatatc tttttactat tcttcatatt attttctacc cccaatgtac
     9961 ttttcatatt ttttattagt actcatactt atttttaatc aaaagttaca attttgttac
    10021 catattttat atatgatacc atagttatcc atacaactca aacaatatac ctaaagtttt
    10081 tattctctat aaattcaaaa cattataatt tattttattt aattaagtta t
//
LOCUS       DAMJYN010000110         9795 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.115, whole genome shotgun sequence.
ACCESSION   DAMJYN010000110 DAMJYN010000000
VERSION     DAMJYN010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9795)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9795)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9795
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.115"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            80..1951
                     /locus_tag="PC466_003236"
     CDS             80..1951
                     /locus_tag="PC466_003236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp2"
                     /protein_id="HDF2770592.1"
                     /translation="MNKKNLSVIMAAAMISTSVAPVFAAETTQVKKETITKKEATELV
                     SKVRDLMSQKYTGGSQVGQPIYEIKVGETLSKLKIITNIDELEKLVNALGENKELIVT
                     ITDKGHITNSANEVVAEATEKYENSADLSAEANSITEKAKTETNGIYKVADVKASYDS
                     AKDKLVITLRDKTDTVTSKTIEIGIGDEKIDLTANPVDSTGTNLDPSTEGFRVNKIVK
                     LGVAGAKNIDDVQLAEITIKNSDLNTVSPQDLYDGYRLTVKGNMVANGTSKSISDISS
                     KDSETGKYKFTIKYTDASGKAIELTVESTNEKDLKDAKAALEGNSKVKLIAGDDRYAT
                     AVAIAKQTKYTDNIVIVNSNKLVDGLAATPLAQSKKAPILLASDNEIPKVTLDYIKDI
                     IKKSPSAKIYIVGGESAVSNTAKKQLESVTKNVERLAGDDRHMTSVAVAKAMGSFKDA
                     FVVGAKGEADAMSIAAKAAELKAPIIVNGWNDLSADAIKLMDGKEIGIVGGSNNVSSQ
                     IENQLADVDKDRKVQRVEGETRHDTNAKVIETYYGKLDKLYIAKDGYGNNGMLVDALA
                     AGPLAAGKGPILLAKADITDSQRNALSKKLNLGAEVTQIGNGVELTVIQKIAKILGW"
     gene            2058..2765
                     /locus_tag="PC466_003237"
     CDS             2058..2765
                     /locus_tag="PC466_003237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HDF2770593.1"
                     /translation="MVDATLFFTPHQDDETLSMGSAIIEHVEKSDTHVILCTDGSKSI
                     IRKVLDDGGSCSYHIKDVHKYSLSESEFSKDRDEEFKDSCEAMGVKESNIHIEDNRAH
                     DGELSKEKAREIILKYLEEYPDAKVKTVTPFKASGIHEDHRALGEAALELYKEGKIKD
                     LRFYVEPYDYKDFKKVNPNVEVWKVLPSQEEKLLSAMNAYKKWNPESGHYAIGYHSVK
                     SHFDELAINKIQYVHAP"
     gene            2798..4633
                     /locus_tag="PC466_003238"
     CDS             2798..4633
                     /locus_tag="PC466_003238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HDF2770594.1"
                     /translation="MKISKKIVSLLTMTFLTVTLYGNTSNASTKDTLTGSGRWETAIK
                     ISQAGWKKSENAVLVNDNSIADALSATPFAKAKDAPILLTQSNKLDSRTKAELKRLGV
                     KNVYLIGGSIALSSEIEKQLNAENISFERISGNSRYDTSLKLAEKLDREKSISKIVVV
                     NGEKGLADAVSVGAIAAQENMPIILSDSENGTEVADNFIDSKDIEKSYVIGGTYSISN
                     SVERSLPNATRIAGSSRSETNAKIIEEFYKDTDIKNIYVTKDGTRSKHDLIDSLAVGV
                     LASKNGSPILLAGNKLDSSQKDVLNTKIIDKVIQIGGLGNENVVEDVIDMQEETKYTV
                     ETIDELNVAIKKSDANDIIRFKPEKDKNITNSFKIETNKAITIEFDGIYKQSITIDMP
                     NGDIKNFGDIDNDLVINNIKNETLVNEGSIQGIDVYDENGCKIENEDSGEIWLITILK
                     NSKDVYILNRGEITKISNNSSSVTIKNSGNINTISGSEEPSISGKKPITNDTDKDEDK
                     KARGLYPKVESCIPALKDYVRITISTKPESSKYKIYYRVVDEKPSAKYVGEKISTKGW
                     SMVTISNQSFIERAKDGSYIEAVEIDTSNNEVSRWGKSSITDDGI"
     gene            complement(4681..5076)
                     /locus_tag="PC466_003239"
     CDS             complement(4681..5076)
                     /locus_tag="PC466_003239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HDF2770595.1"
                     /translation="MILKKHRETILYLFFGAFTTLVNIVSYLFFTRVILFNFMVANAL
                     AWILAVLFAYVTNKFFVFESKRIEIRFVFKEFLSFVSFRLLSGVVEMLIMYVMIDLLF
                     VNDVIVKIFTNIVVIVLNYLFSKMIIFKK"
     gene            5303..7714
                     /locus_tag="PC466_003240"
     CDS             5303..7714
                     /locus_tag="PC466_003240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding cysteine protease Cwp84"
                     /protein_id="HDF2770596.1"
                     /translation="MRKYKSKKLSKLLALLTVCFLIVSTIPVSAENHKTLDGVETAEY
                     SESYLQYLEDVKNGDTAKYNGVIPFPHEMEGTTLRNKGRSSLPSAYKSSVAYNPMDLG
                     LTTPAKNQGSLNTCWSFSGMSTLEAYLKLKGYGTYDLSEEHLRWWATGGKYGWNLDDM
                     SGSSNVTAIGYLTAWAGPKLEKDIPYNLKSEAQGATKPSNMDTAPTQFNVTDVVRLNK
                     DKETVKNAIMQYGSVTSGYAHYSTYFNKDETAYNCTNKRAPLNHAVAIVGWDDNYSKD
                     NFASDVKPESNGAWLVKSSWGEFNSMKGFFWISYEDKTLLTDTDNYAMKSVSKPDSDK
                     KMYQLEYAGLSKIMSNKVTAANVFDFSRDSEKLDSVMFETDSVGAKYEVYYAPVVNGV
                     PQNNSMTKLASGTVSYSGYINVPTNSYSLPKGKGAIVVVIDNTANPNREKSTLAYETD
                     IDGYYLYEAKANLGESYILQNNKFEDINTYSEFSPCNFVIKAITKTSSGQATSGESLT
                     GADRYETAVKVSQKGWTSSQNAVLVNGDAIVDALTATPFTAAIDSPILLTGKDNLDSK
                     TKAELQRLGTKKVYLIGGENSLSKNVQTQLSNMGISVERISGSDRYKTSISLAQKLNS
                     IKSVSQVAVANGVNGLADAISIGAAAADNNMPIILTNEKSELQGADEFLNSSKITKSY
                     IIGGTATLSSNLESKLSNPTRLAGSNRNETNAKIIDKFYPSSDLKYAFVVKDGSKSQG
                     DLIDGLAVGALGAKTDSPVVLVGNKLDESQKNVLKSKKIETPIRVGGNGNESAFNELN
                     TLLGK"
     gene            8011..9588
                     /locus_tag="PC466_003241"
     CDS             8011..9588
                     /locus_tag="PC466_003241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp5"
                     /protein_id="HDF2770597.1"
                     /translation="MKAPKTILTILTIALTLSSISIIPSYALTEEKLIGNGRYETAVK
                     ISQKAYSSSSNVVLVNDNSLADALSATPFAKAKGAPILLTESDKLDDRTEKEIKRLGA
                     KDIYLIGGTAVLNKDIENKLKGNGLNVERINGKDRYETSLILANKLKDIKDIKEVAVV
                     NGEKGLSDAVSVGAPAAQNKMPIILSSPKDGVEAFDKFIRDEKVIKAYVIGGTNSVSR
                     AVEKSLPNAERVSGKDRNETNAKVIEKFYTDTNLSNLYVTKDGSKNENQLIDSLAVGV
                     LAAKNESPVVLVGNKLNTKQRDILSTKKLNTITQVGGNGNEEAFDEIKSLQEKTVFEA
                     KTVEELTDMINIASPNDIINFKPKENTVNEAFRMVTNKPITVNIKGDCSKTLTVDMPN
                     GEVNNYATLVNVIVRNIGEGGFNNHDTITILSVRDKNGRVIENTRNSDIDTLMILASA
                     NDTKLINDGYIGKLIDNSSNSDITNNGTIDKKVNQVENLEAKVDSIEKAIDSISQKVN
                     KIQDILDKIGFLKKFLS"
BASE COUNT         4075 a         1135 c         1756 g         2829 t
ORIGIN      
        1 aaataatatc aaatatatat tataattggt aaataaggaa aaaataataa aaatttgaat
       61 tttttagggg gaaaatacca tgaataaaaa aaatctttct gtaattatgg ctgctgcaat
      121 gataagtaca tcagtagctc cagtttttgc tgcagaaact acacaggtaa aaaaagaaac
      181 aataactaag aaagaagcta cagaactagt ttcgaaagtt agagatttaa tgtctcaaaa
      241 gtatactggt ggttctcaag ttggacaacc aatatatgaa ataaaagttg gcgagacttt
      301 atcaaaatta aaaataataa ctaatataga tgaattagag aaattagtaa atgctttggg
      361 agaaaataaa gaacttattg taactataac agataaaggg catataacaa atagtgcaaa
      421 tgaagtagtt gcagaagcaa ctgaaaaata tgaaaattca gcagaccttt ccgctgaggc
      481 taattctata acagaaaaag ctaaaactga aactaatgga atttataaag ttgcagatgt
      541 aaaagcttca tatgatagtg ctaaagataa gttagttata actttaagag ataaaacaga
      601 cacagtaact tctaaaacta tagagatagg tattggtgat gaaaaaattg atttaacagc
      661 aaatccagtt gattcaacgg gaacaaactt agacccttct acagaaggat ttagagtaaa
      721 taaaatcgtt aaactaggtg tagcaggagc taaaaatatt gatgatgtcc aattagctga
      781 aataactata aaaaatagtg acctaaatac agtttcacca caagatttat atgatggata
      841 tagattaact gttaaaggta atatggtagc aaatggaaca tcaaagtcaa ttagtgatat
      901 ttcatcaaaa gattcagaaa caggaaagta taaatttact attaagtata ctgatgcatc
      961 tggaaaagca atagagctta ctgtagaaag tactaatgaa aaagatttaa aagatgccaa
     1021 agctgcatta gaaggtaatt caaaggttaa attgatagct ggagatgata gatatgcaac
     1081 tgcagtggct atagcaaaac aaacaaaata tactgacaat atagttatag ttaattcaaa
     1141 taaactagtt gatggattag cagctacacc acttgctcaa tctaaaaaag cacctatatt
     1201 attagcatcc gataatgaaa taccaaaagt aactttagat tatataaaag atataattaa
     1261 gaaaagccca tcagctaaaa tatatatagt aggtggagaa tcagcagtat caaatacagc
     1321 taaaaagcaa ttagaatcag taactaagaa tgttgaaaga ctagctggag atgatagaca
     1381 tatgacttct gtagcagtag caaaagctat ggggtctttt aaagatgcat ttgtagtagg
     1441 tgcgaaaggg gaggctgatg ctatgagtat agctgccaaa gctgctgaac ttaaggctcc
     1501 tataatagta aatggctgga atgatctttc agcagacgct atcaaattga tggatggaaa
     1561 agagattggt atagttggtg gttctaacaa tgtatctagt caaattgaaa atcaacttgc
     1621 tgatgttgat aaagatagaa aagttcaaag agttgaagga gaaacaagac acgatactaa
     1681 tgctaaggtt atagaaacat attatggaaa attagataaa ctatatatag caaaagatgg
     1741 atatggaaat aatggtatgc tagtagatgc attggcagca ggacctctag cagcaggtaa
     1801 aggtccaata cttctagcta aagctgatat aacagactca caaaggaatg cacttagtaa
     1861 aaaattaaat cttggtgcag aagtaactca aataggtaat ggagttgaat tgacagtaat
     1921 acaaaagata gctaaaatac taggttggta ataacttata ctgtggagaa gattccttaa
     1981 ttaatacagg aatctttttc tataattatg ctatttattg taaattataa cattttataa
     2041 agtaggagga tgtagtagtg gtagatgcaa ctttattttt tacaccacat caagatgatg
     2101 aaaccttaag tatgggaagt gctataattg aacatgttga aaaaagtgat acacatgtca
     2161 tattatgcac agatggtagt aaatctataa taagaaaagt tttggatgat ggagggtcat
     2221 gttcttatca tattaaagat gttcataaat actctttatc agaaagtgaa ttttcaaaag
     2281 atagagatga agaatttaag gatagctgtg aagcaatggg tgtaaaagaa agtaatatac
     2341 atatagaaga taatagagca catgatggtg agttaagtaa agaaaaggca agggaaataa
     2401 tacttaagta cttagaagaa tatccagatg caaaagtaaa aactgttact ccgtttaaag
     2461 ctagtggaat acatgaagac catagggcat taggagaagc tgcactagag ttatataaag
     2521 aaggcaaaat aaaagattta agattttatg tagaaccata cgactataag gattttaaaa
     2581 aagttaatcc aaatgtagag gtatggaagg tattacctag tcaagaggag aagttattaa
     2641 gtgcaatgaa tgcatataaa aaatggaatc ctgaaagtgg acattatgct ataggatatc
     2701 attcagtaaa atctcatttt gatgagctag ctataaataa aatacagtat gtacatgctc
     2761 cataaaatat tatgaaagaa ttaggaggta agaattaatg aaaatatcaa aaaagatagt
     2821 gtctttgtta actatgacat ttttaactgt tacattatat ggaaatacat ctaatgcatc
     2881 tacaaaagat acattaacag gttctggaag atgggaaaca gcaataaaaa taagtcaagc
     2941 aggatggaaa aagtctgaaa acgctgtgct agtaaatgat aattcaatag cagatgcttt
     3001 atcagctact ccatttgcta aagcaaaaga tgcaccaata ttattaactc aaagtaataa
     3061 attggatagt agaacaaaag cagaattaaa aagacttggt gtgaaaaatg tatatttaat
     3121 aggtggttca attgcattaa gttcagagat tgaaaagcag ttaaatgcag aaaatataag
     3181 ttttgaaaga atatctggaa atagtagata tgatacttct ttaaaattag ctgaaaagct
     3241 agatagggaa aaatctatat ctaaaatagt agtagtaaat ggagaaaagg gtcttgctga
     3301 tgcagtgagt gttggagcta tagctgctca agaaaacatg ccaataatac tttctgattc
     3361 agagaatgga actgaagtag ctgataattt tatagatagt aaagatatag aaaaatcgta
     3421 tgtaataggt ggtacatatt ctatttctaa ttctgtagaa agaagtttac caaatgcaac
     3481 aagaatagca ggtagtagta gaagtgagac aaatgcaaaa attatagaag aattttacaa
     3541 agatactgat ataaaaaata tttatgtaac aaaggatggt acaaggagta agcatgattt
     3601 aatagattct ttagctgtgg gtgtattagc ttctaaaaat ggttctccaa tacttttagc
     3661 aggaaataag ctagatagtt ctcaaaaaga tgtgttaaac actaaaatta tagataaagt
     3721 tattcaaatt ggcggattgg gtaatgaaaa tgttgtagaa gatgtaatag atatgcaaga
     3781 agaaactaag tatactgttg aaactattga tgaacttaat gttgctataa aaaaatcaga
     3841 tgcaaatgac atcataagat ttaagccaga aaaagataaa aatataacta attcttttaa
     3901 aatagaaaca aataaagcta taactattga atttgatggt atatataaac aatcaataac
     3961 tatagatatg ccaaatggag atataaaaaa ctttggggac atagataatg atctagtaat
     4021 aaataatata aaaaatgaga ctttagttaa cgaaggaagt atacaaggga tagatgttta
     4081 tgatgagaat ggatgtaaaa tagagaatga ggattctgga gaaatatggc ttataacgat
     4141 acttaaaaat tcaaaagatg tatatatttt gaatcgtgga gaaataacta aaatatctaa
     4201 taattcttct agtgtaacaa taaaaaattc aggtaatatt aatactataa gtggaagtga
     4261 agaaccatca ataagtggta aaaaacctat aactaatgat acagataaag atgaagataa
     4321 aaaggcacgt ggtttatatc ctaaagtaga atcttgtata cctgctttaa aagattatgt
     4381 aagaataact atatcaacaa aaccagagag ttcaaagtat aaaatttatt atagagtagt
     4441 tgatgaaaaa ccatctgcga aatatgttgg agaaaaaatt agtactaaag gttggagtat
     4501 ggttacaata tcaaatcaat cttttattga aagagccaaa gatggatcat atatagaagc
     4561 agtagaaata gatacctcaa ataatgaagt ttcacgatgg ggaaaatcta gcattacaga
     4621 tgatggaatt tagacattaa acttattcat tttgcagatt actatttagt aatctgctat
     4681 ttatttttta aaaattatca tcttgctaaa caagtaattt aaaactataa caactatatt
     4741 agtaaatatt tttacaataa catcatttac aaaaagcaaa tcaatcatta catacataat
     4801 taacatttca acgacaccag aaagtagcct aaaactaaca aaagacaaaa attctttaaa
     4861 tacgaacctt atttcaattc ttttactttc aaatacaaaa aacttattag taacataagc
     4921 aaataaaaca gcaagtatcc atgccaaagc atttgcaacc ataaaattaa ataaaataac
     4981 tctagtaaaa aataaatacg aaactatatt tacaagagta gtaaatgctc caaaaaataa
     5041 atataatatt gtctctctat gcttttttaa aatcaaatat aatcctccta atctaattta
     5101 atataaatat acttaaagat actaacaaac attagtatag cacatctatt aataaatcaa
     5161 tatatcttaa aatattataa aaataaaact ataatattct ataattaata tgtactcata
     5221 atccatattt tatcaaaata aaatatgacc ttaatttaga aatctgatat aataaaaatt
     5281 aaatacatat aagggggtaa acatgagaaa gtacaaatca aaaaaattgt caaagctact
     5341 ggcattgttg acagtttgct ttttaatagt gtcaacaata cctgtctcag cagaaaacca
     5401 taaaactcta gatggagtag aaactgcaga gtattctgaa agttatcttc aatacctaga
     5461 agatgtcaaa aatggagaca cagcaaaata taatggagta ataccttttc cacatgaaat
     5521 ggaaggtaca acacttcgaa ataagggcag aagtagtctt ccatcagcat ataaatcaag
     5581 tgtagcatac aacccaatgg atcttggtct tactacacca gcaaaaaatc aaggaagtct
     5641 taatacatgc tggtcttttt caggtatgtc aactttagaa gcatatctta aattaaaggg
     5701 atatggaacg tatgacttat cagaagaaca tttaagatgg tgggcaactg gtggaaaata
     5761 tggatggaac ttagatgata tgtcaggtag ttcaaatgta acagccatag gatatctgac
     5821 agcatgggca ggtcctaagt tagaaaaaga tataccatat aatcttaaat ctgaggcaca
     5881 aggtgcaact aaaccttcaa atatggatac tgcacctact caatttaatg taacagatgt
     5941 tgttcgtctt aataaagata aggaaactgt aaaaaatgct ataatgcaat atggttcagt
     6001 gacatcaggt tatgcacatt attcgacata ttttaataaa gatgaaacag catataactg
     6061 tacaaataag agggctccat taaatcacgc tgtagcgata gtaggatggg atgataatta
     6121 ttcaaaagat aactttgcat ctgatgtaaa accagaatca aatggagcat ggttagtaaa
     6181 aagcagttgg ggagaattta attctatgaa aggattcttc tggatttctt atgaagataa
     6241 aactctacta acagatacag ataactatgc aatgaaatca gtatcgaaac cagatagtga
     6301 taaaaaaatg taccaacttg aatatgctgg tcttagtaag ataatgtcaa ataaagtaac
     6361 agcagcaaat gtatttgatt ttagcagaga ttctgaaaaa cttgactctg ttatgtttga
     6421 aacagactct gtaggagcaa aatatgaagt atattatgca ccagtagtaa atggagttcc
     6481 tcaaaacaac tcaatgacaa aacttgcaag tggaacagta tcatattctg gatacataaa
     6541 tgtacctact aattcttaca gcttaccaaa aggtaaagga gcaatagtag tagttataga
     6601 caacacagca aatcctaata gagaaaaatc aactttagca tatgaaactg atatagatgg
     6661 atactatcta tatgaggcta aagcaaactt aggtgaaagc tacatacttc aaaacaataa
     6721 gtttgaagat ataaatacat atagtgaatt ttctccttgt aactttgtta taaaagctat
     6781 aacaaaaaca tcttctggac aagctacttc aggagaatct ttaactggag cagatagata
     6841 tgaaacggca gttaaagtta gtcaaaaagg atggacttct tcacaaaatg cagtattagt
     6901 aaatggagac gcaatagtgg atgctttaac agctacacca tttacagcag caatcgactc
     6961 tccaattctt ttaacaggaa aagataactt agattcaaaa actaaggcag agttacaaag
     7021 attaggaact aaaaaagttt atctaatagg tggagaaaat tctttaagca agaatgtaca
     7081 aactcaactt agtaatatgg gtatatcagt agaaagaatt tcaggtagtg atagatacaa
     7141 gactagtata tctctagctc aaaagttaaa tagtataaaa tctgtttcac aagttgcagt
     7201 ggcaaatggt gtaaatggac ttgcagatgc aataagtatt ggtgcagcag ctgctgataa
     7261 caatatgcca ataatactta ctaatgaaaa gagtgagttg caaggtgctg atgagttttt
     7321 aaattcatca aaaataacta agtcttatat aattggtggt acagctactt tatcatcaaa
     7381 tttagaaagt aagctttcaa atccaacaag acttgcagga agtaatagaa atgaaactaa
     7441 tgctaagata atagataaat tctaccctag ctcagatttg aaatatgctt ttgttgttaa
     7501 agatggttca aagagtcaag gagacttgat agatggacta gcagtaggag cattaggtgc
     7561 taaaactgat tcaccagtag ttctagttgg aaataagtta gatgaaagtc aaaaaaatgt
     7621 acttaagtct aagaaaatag aaactcctat tagagttggt ggaaatggaa atgaaagtgc
     7681 ttttaatgaa ctaaatactc ttttaggaaa atagtgaatg gaaagatagt aaggatatac
     7741 attttattat taaaaaatat tcaatagaag tttataaata taaaataaca aaaaggggtg
     7801 tctcaaaatg aactttttag ttcatgaggc actctttttt gttgttttat atttttatca
     7861 tttaaataat gaaaaatagg cttgtctata tttttagata gttttcttat tattgatgaa
     7921 aaatgtaata attttaaact gtaaaatagt gtaaagttat tttataatat aaatatagta
     7981 agattttaaa caaaataagg gggaataata atgaaagcac caaaaactat tttaacaata
     8041 ctgacaatag cgcttacttt aagtagcatt tctataatac catcatatgc acttacagag
     8101 gaaaaattaa taggtaatgg tagatatgaa actgctgtaa agataagtca aaaggcatac
     8161 agttctagtt ctaatgtagt gttagttaat gacaattcat tagctgatgc actttcagct
     8221 acaccatttg caaaggctaa aggagcacca atacttttga cagaaagtga taagctagat
     8281 gataggactg aaaaagagat aaaacgtcta ggagctaaag atatttattt gataggaggt
     8341 actgctgtac ttaataaaga tatagagaac aagttaaaag gtaatggact taatgtagaa
     8401 agaattaatg gtaaggatag atatgaaact tcactgattt tggctaataa gcttaaggat
     8461 ataaaagata ttaaggaagt tgctgtagta aatggtgaaa aaggattaag tgatgctgtt
     8521 agtgttggag caccagcagc tcaaaataag atgcctataa ttttgtctag tcctaaggac
     8581 ggagtagaag catttgataa atttataaga gatgagaaag ttataaaagc atacgtaatt
     8641 ggaggaacaa attctgtttc aagagctgta gaaaagagcc ttcctaatgc agaaagagtg
     8701 agtggaaaag atagaaatga gactaatgcc aaagttatag aaaagtttta tactgataca
     8761 aatttaagta atttatatgt aactaaggat ggtagtaaaa atgagaatca actaatagac
     8821 tcgttagctg ttggagtatt ggctgcaaaa aatgagtctc ctgttgtttt ggttggtaat
     8881 aaattaaaca cgaaacaaag ggatatactt agtactaaaa aattaaatac tataacacag
     8941 gtaggtggaa atggaaatga agaagctttt gatgaaatta agagtttaca agaaaaaact
     9001 gtgtttgaag caaaaactgt tgaggaatta actgatatga taaatatagc aagtcctaat
     9061 gatattataa actttaaacc aaaagagaat actgtaaatg aagcttttag aatggtaaca
     9121 aataaaccaa taactgtgaa tataaagggt gattgttcaa agactcttac agtagatatg
     9181 cctaatggtg aagtgaataa ctatgctact ttggtaaatg ttatagttag aaatattgga
     9241 gaaggtggat ttaataacca tgatacaatc actatattgt cagttcgtga caaaaatggt
     9301 agagttatag aaaatactag aaattcagat atagatacgt tgatgatatt agcttctgct
     9361 aatgatacaa aattgattaa tgatggatat ataggaaagc ttatagataa ttcatctaat
     9421 agtgatataa ctaataatgg tactatagat aaaaaagtta atcaagttga gaatttagag
     9481 gctaaagtag attcaattga aaaagctata gattctataa gtcaaaaagt caataaaata
     9541 caagatatac tagataagat tggatttcta aagaaatttc ttagttaaga atatgtatat
     9601 ttaagtgaag tgtgtgttgt aattgttcta aagttatata gttaaacagg tttatataca
     9661 aacagactta tagataaata tgtagtttag tatatatttg aataagcttt ggggaggtaa
     9721 catggggatt ggaattgaat gtaacaaaaa aataaataaa agtattgaca aaactagaat
     9781 aaagaaaaat aatct
//
LOCUS       DAMJYN010000111         9726 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.116, whole genome shotgun sequence.
ACCESSION   DAMJYN010000111 DAMJYN010000000
VERSION     DAMJYN010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9726)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9726)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9726
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.116"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            90..764
                     /locus_tag="PC466_003242"
     CDS             90..764
                     /locus_tag="PC466_003242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2770598.1"
                     /translation="MFKIMVVEDDVSLKNIIAKCLTKWGHDVHQIENLENIIEEFKNY
                     NPELVLLDINLPFYDGFHWCNEIRKISKVPIIFISSRNSNMDVIMGVNLGADDYIQKP
                     FSVDVLVAKVNALLRRTYNFVDNNSNQIIHNGVTLDLSTATINYEDNTIELTKNEIKI
                     LHELMKYKGQIVSRNKLMKKLWDNDWFVDDNTLTVNVNRIRSKLNEIGLEDFIETKRG
                     LGYIIS"
     gene            788..1792
                     /locus_tag="PC466_003243"
     CDS             788..1792
                     /locus_tag="PC466_003243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2770599.1"
                     /translation="MSFKDFLKDKLGFLVYNFTFLIFTVSVIIFSPVDVFLTDTILYI
                     LVVNVVFLFLYLFISYIKKNKFLDKIKNDTFKINMNDIELARCKNEEKIYLNIIKNHQ
                     YQCNNIINNNIEKFEENKEILNMWVHDVKIPIAIIKLILEQNENLINEKISDDIDSEI
                     FRIENSVEKILYLSRLEDFHKDFLIQEVNIEKIIRNIIKKYSKYFISKKIILDLNNLN
                     FKVLSDEKWLYFIFEQLLSNSLKYSSLGDNISIYCKRTKNYLQLRVEDTGCGIKKEDL
                     NRIFNKGFTGNNGRNNSKSTGLGLYLVKELCDKLGHKIDVDSEYNQYTKFTITFKCDL
                     "
     gene            1904..3133
                     /locus_tag="PC466_003244"
     CDS             1904..3133
                     /locus_tag="PC466_003244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HDF2770600.1"
                     /translation="MSFLKKFKNKRFRNNSFKSNNFRNSSFGSSGFKSKNKGFKNNPF
                     KNKRFKIYAGIAVIILLILGVLAYVDSKNTELQANENFIETYTIPENEKIFINGMVVP
                     KQTKDFNISGDYELSDVNVTNGQKVNQGDLLFTAKNPTIIAEIDSLKSQLSQYKKQKI
                     SLSDIAENKDAIASINAQITALNSQIASLDKKAYDRVTAPFDGTVYLNDQTGNPDQPV
                     SFMTIQGLEFYMKGQASEQDLPKMKIDQMVNILVFSTDQKLTGRISFISDKPSTPNTE
                     MGAQQNTLSYYDINIAFDNQEGLVNGFHLQASLEVANSSFKIPASCVLKDNKHSYVFK
                     DLDGILKKQIVDVASQNDDFAVVRGGLEQGDIIIKHPTKEMKEGDPVQGDGVTAGSNN
                     GDTTPNKKVEEVTMDVN"
     gene            3141..3815
                     /locus_tag="PC466_003245"
     CDS             3141..3815
                     /locus_tag="PC466_003245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2770601.1"
                     /translation="MLIKLENIQKYYKVGKDELHVLKSLNLEIESGEFVMIMGKSGSG
                     KTTLLNILGFLDVFDEGRYIFDGTDVTNLSENERSVFRNINIGFVFQQFNLIETLNVY
                     QNVELPLIYNKALKKSNREEIVKDKLSSVGLLDKLKQKPLQLSGGQQQRVAIARCLVN
                     DPQIIFADEPTGALDSETSREIMELLTRLNKQGKTIIMVTHDQDLTKYATKVIRLKDG
                     VFTSEV"
     gene            3818..5050
                     /locus_tag="PC466_003246"
     CDS             3818..5050
                     /locus_tag="PC466_003246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2770602.1"
                     /translation="MSLLKNSLANLKGHKLRVFVALLWIIIGITSVILVSSIGNGFQK
                     EIKKSVNNVNPNKTTISFESADNTGLTDDMSIFLKPFNAKDLEELSFVEGVERIAPSR
                     DGFNLDSVYSSQASFDKKTTYVDVGPVKKDSKINLICGRDFSLDDEKRKVILLTLQST
                     SEIFENPEDALGHGININGTIFEIIGVLDDSQQNQAGGFFGGYQDMQFTTSLVPKKAF
                     DTLMSQNSYSNEIYQLDLVSSKGYNVNEVANNVIAKLYEMHPGINGSYTTPDPTEQTA
                     YLESINSNVNKYVSIITVVAMFVGGIGVMNIMYVSVMERQREIGIRRAIGAKPRSILF
                     QFLVEAVFITVCGGILGTIVGFAATNYVSKYIGFEAIPSLNSLFYAIVATILTGVVFG
                     LIPAFKASKLDPIKAIYK"
     gene            complement(5336..6601)
                     /locus_tag="PC466_003247"
     CDS             complement(5336..6601)
                     /locus_tag="PC466_003247"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HDF2770603.1"
                     /translation="MILIKNGRVIDPKSQRDENIDLIIKENKIYKIGKFDESDEYEKI
                     IDASGNVVAPGLVDVHVHFRDPGFTYKEDIESGAKSAARGGFTTVICMANTNPIVDNE
                     DTFNYVKEKSKNACINVLQAAAITKGFEGKELVDMEALKKAGVPGFTDDGLPLMDSNL
                     IMEAMIKAKELDVPLSFHEEDPSLVGNPGVNAGKVASELGLKGASSVAEDVMVARDCM
                     LALKTGAKVDIQHISSGVSVDMVRFAKYLGANVVAEASPHHFTLTEEDVLEFGTNAKM
                     NPPLRSKWDRDKIIEGLNDGTIEIIATDHAPHSKEEKDREFIKAPSGIIGLETSLALG
                     ITNLVHKNHLSMMQLIEKMSINPAKLYNLNIGFIEEGAVADIVIFNPEEEWTVESFVS
                     KADNSPFKGKSLYGKVNYTICNGEIVYNA"
     gene            complement(6654..7802)
                     /locus_tag="PC466_003248"
     CDS             complement(6654..7802)
                     /locus_tag="PC466_003248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF362 domain-containing protein"
                     /protein_id="HDF2770604.1"
                     /translation="MKSVSVRSCKTYNYEEVKLSIEKNLEDIGGIDKFVKKGSKVLIK
                     PNLLMKKKPEEATTTHPMVVKVVCEKLLELNCDITIADSPGGPYNQNSLKSIYKASGI
                     EEVANELGIKLNYDVSDVKIHSKKAHVLKYMDIIKPIVDSDYIINLCKLKTHIMATFT
                     GGTKNLYGCIAGLKKAEIHYRFPTEELFCENVLLDICDYIKPTLTIMDGIVGMEGDGP
                     SAGTTREIGVLLASQNPYAIDVVACKIISLLPNRVATIRGAIKRGYIQEDFSDIEILG
                     EDIKDLIIKNYKIPNVSKDLRLFSVKLPKFLNEPISKLITPKPVVRFQDCIKCGKCKE
                     ACPASTIEIGTKGAIIDLSKCIRCYCCHELCPKKAIDVKRNFVFKYVK"
     gene            complement(7893..8438)
                     /locus_tag="PC466_003249"
     CDS             complement(7893..8438)
                     /locus_tag="PC466_003249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH peroxidase"
                     /protein_id="HDF2770605.1"
                     /translation="MKKFVCTVCGYIHEGDAAPAQCPVCKVGADKFEEMKGEMVWADE
                     HRIGVAQGVDAEIIEGLRANFTGECTEVGMYLAMSRQADREGYPEVAEAYKRIAFEEA
                     EHAAKFAELLGEVVVADTKENLRVRVDAEYGATDGKLKLAKRAKELGLDAIHDTVHEM
                     CKDEARHGKAFLGLLNRHFGK"
     gene            complement(8661..9605)
                     /locus_tag="PC466_003250"
     CDS             complement(8661..9605)
                     /locus_tag="PC466_003250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HDF2770606.1"
                     /translation="MQKNKKEGALLKKYFGEIGLIFIAIIWGSGFVATQFALDGGLTP
                     LQIITLRFFLAAIIMNLLFFKQIRANMGKKLLKAGGILGIFLFLAFTVQTIGLMYTTP
                     SKNAFITAANVVIVPFIGFILYRRKLDKIGIISSLVALIGIGILSLEADFSINFGDFL
                     TLICSFGFAFHIFFTSEFAKDNNPMALTAIQFTVAFLMSVVVQTFAGQLKMEAELSGY
                     MGTMYLAVFSTTIGFLFQTICQKRVDGTRTAIILSTEAVFGTIFSIIILKELITAKLI
                     IGSILIFVAIITAETKLSFLKSKKVKLKDSEESSLESI"
BASE COUNT         3461 a         1496 c         1307 g         3462 t
ORIGIN      
        1 attattttag gtaataaggt agaaatattt taatttatca agtagaatat agttatgtta
       61 atataactat tttgaattag gaggtaagaa tgtttaaaat aatggtagtt gaagatgacg
      121 tctcattgaa aaatatcata gcaaagtgtc ttactaaatg gggacatgat gttcatcaaa
      181 tagaaaatct tgaaaatata atagaagagt tcaaaaacta taacccagaa ttagttttat
      241 tggacataaa ccttccattt tatgatggtt ttcattggtg taatgaaata agaaaaattt
      301 caaaagttcc tataattttt atttcttcaa gaaattctaa tatggatgta ataatgggtg
      361 taaatttagg tgcagatgat tatatacaaa aacctttttc tgtagatgtc ttagtagcta
      421 aagttaatgc ccttttaaga agaacttata attttgttga taataactca aatcagatta
      481 ttcacaatgg tgttacttta gatttatcaa ctgcaacaat aaactatgaa gataatacta
      541 ttgagctaac aaaaaatgaa atcaaaattc ttcatgagct tatgaaatat aaggggcaga
      601 tagtaagtag gaataaactc atgaaaaaat tatgggataa tgattggttt gtagatgata
      661 atacattaac tgtcaatgta aatagaatac gctcaaaatt aaatgaaatt ggtttagaag
      721 attttataga aacaaaaaga ggattgggtt atataatcag ttaaaacaat tctaagtagg
      781 tgaatttatg agctttaaag attttctcaa ggataaacta ggttttttag tatacaattt
      841 tactttctta atttttacag tatcagttat tatattttct cctgtagatg tttttctgac
      901 tgatactatt ttatatatat tagttgtaaa tgttgtgttt ttatttttat atctatttat
      961 tagctacatc aagaagaaca aatttttaga taagataaaa aatgatacat tcaaaattaa
     1021 tatgaatgat atagaattag ctagatgtaa aaatgaagaa aaaatatact tgaacattat
     1081 taaaaatcat caatatcaat gtaataacat aataaataat aatatcgaga aatttgaaga
     1141 aaacaaagag attttaaata tgtgggtaca cgatgtaaag atacctatag ctataataaa
     1201 actcattctt gaacaaaatg aaaatttaat taatgaaaaa atttcagatg acatagatag
     1261 tgaaatattt agaattgaaa actccgttga aaaaatttta tatttatcaa gactcgaaga
     1321 ttttcataag gattttttaa ttcaagaggt aaatattgaa aaaatcatta gaaatattat
     1381 aaaaaaatac tcaaaatatt ttatttcaaa aaaaattatt ttagacttaa ataatttgaa
     1441 ttttaaggtt ttatctgatg aaaaatggct atacttcata ttcgagcaat tattgagtaa
     1501 ttccctaaaa tactcctcat taggagataa tatatctatc tattgcaaaa gaaccaaaaa
     1561 ttatttacaa ttaagagtgg aagatactgg ttgtggtata aaaaaggaag atttaaatcg
     1621 aatattcaat aagggattta caggtaataa tggaagaaac aattctaaat ctacaggtct
     1681 tgggctttat ttagtaaaag aactttgtga taagcttggt cataaaattg atgtagattc
     1741 agagtacaac caatatacaa aatttactat tacattcaaa tgtgatttat agtatcttat
     1801 tattgatagt ttattttcat taacttatat tcaacttctt atagtaattc tatatgtaca
     1861 tcccagtata taattaagta gtttttataa aaaggaggaa gacatgtctt ttctaaaaaa
     1921 atttaaaaat aaaagattta gaaataacag ttttaaaagt aacaacttta gaaatagcag
     1981 ttttggaagt agtggcttca agtctaaaaa taaaggtttt aaaaacaatc cctttaaaaa
     2041 taagagattc aaaatatatg caggaatagc agtaatcata cttttaattc taggagttct
     2101 tgcttatgtt gattcgaaaa acactgaatt acaagctaat gaaaatttta tcgaaacata
     2161 tactattcct gaaaatgaaa aaatatttat aaatgggatg gttgttccta agcaaactaa
     2221 ggacttcaat atatctggag attatgagtt aagtgatgtt aatgttacaa atggtcaaaa
     2281 agtaaatcaa ggagaccttc tttttactgc taaaaatcca actataatag cagaaataga
     2341 tagtttaaaa tcacaactta gtcaatacaa aaaacaaaaa atatcacttt ctgatattgc
     2401 tgaaaataaa gatgctattg cttctataaa tgcacagata actgctttaa actctcagat
     2461 agcttctctg gataaaaaag cttatgacag agttactgct ccttttgatg gcacagtata
     2521 cttgaatgac caaactggaa atccagacca accagtttca tttatgacta ttcaaggtct
     2581 agagttttat atgaaaggac aagcaagtga acaagattta cctaaaatga agattgacca
     2641 aatggtcaat atactagttt tttcaactga ccaaaagctt actggtagaa taagttttat
     2701 atctgataaa ccatctactc caaatactga aatgggagct cagcagaata cactatctta
     2761 ttatgatata aacatagcat ttgataatca agaaggatta gtaaatggat tccatcttca
     2821 agcatcactt gaagtagcta attcaagctt taaaatacca gcatcttgtg tacttaaaga
     2881 caacaaacac tcatatgtat ttaaggattt agatggtata ttgaaaaagc aaattgtaga
     2941 tgtagcaagt caaaatgatg attttgctgt agttagaggc ggtcttgaac aaggcgatat
     3001 aataataaaa caccctacta aagaaatgaa agaaggagac ccagttcaag gcgatggcgt
     3061 aactgctggt tctaataatg gagatactac tccaaacaaa aaagtagaag aagttactat
     3121 ggatgtgaat taatttacat atgttaatta aattagaaaa tattcaaaaa tattacaaag
     3181 tagggaaaga tgaattacat gttttaaaat ccttaaattt agaaattgaa tctggagaat
     3241 ttgtcatgat aatgggtaag tctggtagtg gtaaaactac tttacttaat atcttaggtt
     3301 ttctagatgt atttgatgaa ggaagatata tatttgatgg aacagatgta actaatttga
     3361 gtgaaaatga acgttctgtt tttagaaata ttaatattgg atttgttttc caacaattta
     3421 atttaataga aactctaaat gtatatcaaa atgtagagtt gcctctaatt tacaataaag
     3481 cactaaaaaa atctaataga gaagaaattg ttaaagataa attaagttct gttgggcttt
     3541 tggacaagct taagcagaaa ccacttcaat tatctggtgg tcaacaacag cgtgtagcca
     3601 ttgcacgttg cctagtaaat gaccctcaga taatctttgc tgatgaaccg actggggcat
     3661 tagatagtga aactagcaga gaaattatgg agcttttaac aaggctcaac aaacaaggta
     3721 agactataat aatggttaca catgatcaag atttaactaa gtatgcaact aaggttatac
     3781 gacttaaaga tggtgtgttt acttcggagg tgtaatcatg agtttattaa aaaattcttt
     3841 ggccaattta aaaggtcaca agcttcgtgt atttgtagct ttactctgga ttataatagg
     3901 aataacttca gtaatacttg ttagttctat aggtaatgga tttcaaaaag aaattaagaa
     3961 atctgtaaac aatgtaaacc ctaataaaac tactatttcg tttgaatcag ccgataacac
     4021 aggtcttact gatgatatga gtattttttt aaaacccttt aatgcaaaag atttagaaga
     4081 attatcattt gttgaaggag tagaaagaat agctccttca agagatgggt ttaaccttga
     4141 ttcagtttac tcttcacaag catcttttga taaaaaaact acgtatgttg atgttggacc
     4201 agtaaaaaaa gattctaaaa taaatttaat ttgtggtaga gatttttctt tagatgatga
     4261 aaaaagaaaa gtaattttac ttacattaca aagtacaagt gaaatttttg aaaatccaga
     4321 agatgcctta ggtcatggta tcaacataaa tggaactata tttgaaataa taggggtatt
     4381 agatgattct cagcaaaacc aagctggagg attctttgga ggttaccaag atatgcaatt
     4441 tactacttcc ctagtaccta aaaaggcttt tgacacttta atgagtcaaa attcttattc
     4501 aaatgaaatt taccagttag acttagtttc ttctaaaggc tataatgtaa atgaagttgc
     4561 aaacaatgtt atagctaaat tatatgagat gcaccctggt atcaatggtt cttatactac
     4621 accagaccca actgaacaga cagcttatct tgaaagcatt aattccaatg taaacaaata
     4681 tgtatctata ataactgtag ttgcaatgtt tgttggtggt attggtgtaa tgaatataat
     4741 gtatgtatct gttatggaaa gacaaagaga aattggtata agacgtgcta ttggagcaaa
     4801 acctaggtct atattatttc aatttttagt tgaagctgtt tttataacag tatgtggtgg
     4861 aattttagga actatagttg gatttgctgc tactaactat gtttctaaat atataggttt
     4921 tgaagctata cctagcttaa atagcttatt ttatgcaatt gtagctacta tattgactgg
     4981 agttgtattt ggtctgattc cagcctttaa agcttctaaa ctagacccta taaaggcaat
     5041 ttataagtag aaattgtata aagattttcg atttttagat tagtttatat aaaacatact
     5101 taaatatata acgcactatt atatatgata gattaggaac ttaatctttc caaatataat
     5161 agtgcgttct ttcataaaaa ggattctctt ccttactata tctaaattac caagatgtta
     5221 tgttctaatt gttcaaacta atacttccaa ttttgattaa tcaatctcat tctgctgata
     5281 tacaatcttt tactttcaat cattgtacac tccgccttaa aaaaataatc ttaaattagg
     5341 cgttatatac aatctcccca ttacatattg tataattaac ctttccatat aaagatttac
     5401 ctttaaacgg tgaattatca gctttagaaa caaagctttc aactgtccat tcttcttctg
     5461 gattgaatat aacaatgtct gctacagccc cttcttctat aaatccaata tttaaattgt
     5521 acaactttgc aggatttata gacatttttt ctattaactg catcatacta agatgatttt
     5581 tatgcaccaa atttgttatt ccaagagcta aagaagtttc aagcccaata attccacttg
     5641 gagcttttat aaactctcta tctttttctt ctttactatg aggtgcatgg tccgttgcta
     5701 ttatttcaat agtaccatca tttaatccct ctataatctt atctctgtcc catttacttc
     5761 ttagaggtgg attcattttt gcatttgttc caaactccaa tacatcttcc tcagtcaatg
     5821 taaagtgatg tggtgaagct tctgcaacta catttgcacc taagtatttt gcaaacctaa
     5881 ccatatcaac agatacacct gaacttatat gttgtatatc aactttagca ccagtcttta
     5941 gtgccaacat acaatctctg gctaccataa catcttctgc tacacttgat gcacctttta
     6001 atcctagttc tgaagctacc tttcctgcat ttacacctgg atttccaact aaagaagggt
     6061 cttcttcatg aaaactaagt ggtacatcca actcttttgc cttaatcatt gcctccataa
     6121 ttagattgct atccattaaa ggtaatccat catcagtaaa ccctggtaca ccagcttttt
     6181 taagagcttc catatcaact aactctttac cttcaaaacc tttagttata gctgctgctt
     6241 gtaaaacatt tatacatgca ttttttgact tttctttaac ataattaaaa gtatcttcat
     6301 tatctacaat aggattagta tttgccatac atataacagt tgtaaatcca cctctagcag
     6361 cagatttagc tccactttct atatcttctt tatatgtaaa cccagggtct ctaaagtgta
     6421 catgtacatc cactaaacct ggagcaacta cattaccact agcatctatt attttttcat
     6481 attcatcact ttcatcaaac ttgcctattt tataaatttt attttctttt ataattaagt
     6541 caatattctc atctctttga cttttagggt ctattactct accattttta attaaaatca
     6601 tattatttct cctttatatt tttaatttat atagactcat ataatattat acattatttt
     6661 acatacttaa atacaaaatt acgtttgaca tcaatagcct ttttaggaca aagttcatgg
     6721 caacagtaac atcttataca tttacttaag tctataatag cacctttagt ccctatctct
     6781 atagtggatg caggacaagc ttccttgcat tttccacatt ttatgcaatc ttgaaatctt
     6841 accacaggct ttggtgttat aagctttgaa ataggttcat ttaaaaattt tggtagcttt
     6901 acggaaaaca atcttaaatc cttacttaca tttggaatct tgtaattttt tataattaaa
     6961 tcttttatat cttcacctaa aatttcaata tctgaaaaat cttcttgtat atagcctctc
     7021 ttaatagcac ctctaattgt agcaactcta tttggaagta aacttataat cttacatgca
     7081 acaacatcta tagcatatgg attttgtgat gctaataaaa ctcctatttc tcgagtagta
     7141 ccagctgaag gtccatcacc ttccatacct actataccat ccataattgt caatgttggt
     7201 tttatataat cacaaatatc taaaagtaca ttttcgcaaa acaactcttc tgtaggaaat
     7261 ctataatgta tctctgcttt tttcaatcct gctatgcatc catataagtt ttttgtacca
     7321 ccagtaaagg ttgccattat atgagtcttt aatttacaaa gatttattat ataatctgaa
     7381 tctactattg gtttaataat atccatatat tttagaacat gtgctttttt actatgtatc
     7441 ttaacatctg aaacatcata atttaactta atgcccagtt catttgctac ttcttcaatt
     7501 ccagatgcct tataaatgct cttaagagaa ttttgattat atggaccacc agggctatct
     7561 gctattgtaa tatcacaatt taactctaaa agtttttcac atacaacttt tacaaccata
     7621 ggatgtgtag ttgtagcttc ttcaggcttt tttttcatta ataaatttgg ttttataagt
     7681 actttgcttc cttttttaac aaacttatct ataccaccaa tatcctctaa atttttttca
     7741 atagataact ttacttcttc ataattgtaa gttttacaac tcctaacaga taccgacttc
     7801 atattatctc catccttcta tcacaacagt ttatttgtat aatttaaaaa aggagaaacc
     7861 aaagtttctc cttttaatct atgttttaat tattattttc caaaatgtct gtttaataat
     7921 cctaagaatg ctttaccatg tctagcttcg tctttacaca tttcatgtac tgtatcatgt
     7981 atagcatcta atcctaattc tttagctctc ttagctaatt ttaattttcc atcagttgca
     8041 ccatactcag catcaactct aactcttaag ttttcttttg tatctgcaac tacaacttct
     8101 ccaagaagtt ctgcaaattt agcagcatgt tcagcctctt caaaagctat tctcttatat
     8161 gcttcagcta cttctggata accttctcta tcagcttgtc tactcattgc taaatacatt
     8221 cctacttctg tacactcacc agtaaagtta gctcttaatc cttcgattat ttctgcatct
     8281 acaccttgag ctactcctat tctatgttca tcagcccaaa ccatttcgcc tttcatttct
     8341 tcaaatttat cagctccaac tttacatact ggacattgtg ctggtgcagc atctccttca
     8401 tgtatatatc cacatactgt acaaacaaat tttttcataa ttaatttcct cccaatttta
     8461 tataattaaa tttttatttt taagtttaat aacttgctac aagaatatat ataccccaga
     8521 ctttatagct taaacactaa aaataaaatt tatttcctaa ttaattttat cactttgaaa
     8581 caccagtatc aaccaagttt tgatgtcaaa tttctacata atacataact tatttgatta
     8641 attaggaaat agttgtcata ttaaatactt tctaatgaag actcctctga atctttaagt
     8701 ttcacttttt tgctctttaa aaaagataat ttagtttctg cagttatgat tgcaacaaat
     8761 atcaagatac taccaataat caattttgct gtaataagtt cctttagaat tattatagaa
     8821 aatattgtac caaatacagc ctctgtggat aatattatag ctgttctagt tccatcaact
     8881 cttttttgac atatagtctg aaataaaaat ccaattgtag tactaaatac agctagatac
     8941 atagttccca tataaccaga taattcagct tccatcttta attgacctgc aaatgtttga
     9001 actacaacag acattaaaaa cgctactgta aattgaatag ctgtcaatgc cattgggttg
     9061 ttatcttttg caaactcact tgtaaagaat atatgaaatg caaatccgaa tgaacatata
     9121 agtgttagaa aatctccaaa attaatagag aaatcagctt ctaaagaaag tatcccaatt
     9181 cctataagag ctaccaaact acttattatt cctattttat caagttttct tctataaagt
     9241 ataaatccta tgaacggaac tattacaaca ttagctgctg ttataaatgc atttttagat
     9301 ggtgtagtgt acataagtcc aatagtttgt actgtgaatg ctagaaataa aaatattcct
     9361 aaaatccctc ctgcttttaa taatttttta cccatattgg cacgaatctg tttaaaaaac
     9421 agtaaattca taattatagc tgccaagaaa aatcttaaag ttatgatttg tagaggtgta
     9481 agcccaccgt ctaatgcaaa ttgggttgct acaaagccac ttccccatat aattgctata
     9541 aatattagtc ctatttctcc aaagtatttt ttcaataaag ccccctcctt tttatttttt
     9601 tgcaaaatta taaaccccct aaacagcaag agagtttttc tataagcatt actataaatt
     9661 aatatagtaa attttttcag tattttaaat ctaaatttac atacattttg agctcaaatt
     9721 tatatc
//
LOCUS       DAMJYN010000112         9614 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.117, whole genome shotgun sequence.
ACCESSION   DAMJYN010000112 DAMJYN010000000
VERSION     DAMJYN010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9614)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9614)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9614
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.117"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            128..1531
                     /locus_tag="PC466_003251"
     CDS             128..1531
                     /locus_tag="PC466_003251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDF2770607.1"
                     /translation="MEKKKIGLWSLVFMNVSALYGIRWIAKSTASSFGLGLGAIPMWL
                     LFSFIYFVPGALICAELASTYQKGDGGLYDWVKEAFGEKYGFLVSWLNWTAKIFWYSS
                     FLTFLAVNVSYTIGNPALADNKMFVLILSLIIFWALSLIATKGISFTKIFTNTGALGS
                     TIPSAILIIFSFVAVFMLKKHDIASTYTIASMTPKLNMDAFVAISAIMFGLAGAETAA
                     NFITEIDKPEKNFPKAILISAGIVASLYVLGSIAITMIIPPDQITASKGVLDALSAVC
                     TSLGIGSWLVQLIAFGIAFSVLGAIVLYIASPIKMLFGSVKKGIFPDSLVEVNEHKIP
                     SKAVILQAIIVTIILLVTTLMPSVDAIYNVLVTMTALTALFPYVLLYASYIKLRKERP
                     DEIRPYTMAKSTSTCLGLAKMVLVVTVVGILLSAAPVMPTFAENVIYEIEMIGGGLLV
                     ILSGLWLWNRYEKKTAK"
     misc_binding    1622..1862
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            1905..2603
                     /locus_tag="PC466_003252"
     CDS             1905..2603
                     /locus_tag="PC466_003252"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HDF2770608.1"
                     /translation="MNVIGIIGAMDEEVSILVDLMDIRETIKKASLEFYKGILKGKNV
                     VLVKCGIGKVNSALCAQILISEFKVDAIVNTGVAGALNEKLDVNDIVISTDAIQYDVD
                     TTAFGDPKGVIPRMKTSVFKADERLIDAAYKSSVEEVKTHKVLKGRVVTGDKFINSKE
                     LKEELVNDFGGYCGEMEGGAIAHVCYLNNTPFVIIRAMSDKADGSADVTYDVFVHDAA
                     NNSKDIVLNMLKSI"
     gene            2626..3627
                     /gene="trpS"
                     /locus_tag="PC466_003253"
     CDS             2626..3627
                     /gene="trpS"
                     /locus_tag="PC466_003253"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HDF2770609.1"
                     /translation="MSEKKVIFSGAQPSGKMTLGNYLGAIKNWTELQDNYDCYYSIVD
                     LHAITVPQDPKVLRANAIELLAQYIACGLDPEKNTIFIQSHVKEHVELMWVLNTMTYM
                     GELSRMTQFKDKSQKSEANLNAGLFTYPVLMAADILLYQTDLVPVGDDQKQHLELARD
                     LANRFNNRFSPTFVVPEGYYPKGGARVMSLQEPTKKMSKSDSNENAFILLADDSDSIK
                     RKIKRSVTDSLGVVKYNDEQPGIKNLIDIYSNLSKKSVEEIVNMYEGKGYGIFKEDVA
                     EVVSEALRPIREKYVDLLNNKDYLEKIYSMGAEKAEKQARKTLRKVYKKVGFIERRY"
     gene            complement(4279..6909)
                     /gene="cdtB"
                     /locus_tag="PC466_003254"
     CDS             complement(4279..6909)
                     /gene="cdtB"
                     /locus_tag="PC466_003254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094607992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylating binary toxin binding subunit
                     CdtB"
                     /protein_id="HDF2770610.1"
                     /translation="MKIQMRNKKVLSFLTLTAIVSQALVYPVYAQTSTSNHSNKKKEI
                     VNEDILPNNGLMGYYFTDEHFKDLKLMAPIKDGNLKFEEKKVDKLLDKDKSDVKSIRW
                     TGRIIPSKDGEYTLSTDRDDVLMQVNTESTISNTLKVNMKKGKEYKVRIELQDKNLGS
                     IDNLSSPNLYWELDGMKKIIPEENLFLRDYSNIEKDDPFIPNNNFFDPKLMSDWEDED
                     LDTDNDNIPDSYERNGYTIKDLIAVKWEDSFAEQGYKKYVSNYLESNTAGDPYTDYEK
                     ASGSFDKAIKTEARDPLVAAYPIVGVGMEKLIISTNEHASTDQGKTVSRATTNSKTES
                     NTAGVSVNVGYQNGFTANVTTNYSHTTDNSTAVQDSNGESWNTGLSINKGESAYINAN
                     VRYYNTGTAPMYKVTPTTNLVLDGDTLSTIKAQENQIGNNLSPGDTYPKKGLSPLALN
                     TMDQFSSRLIPINYDQLKKLDAGKQIKLETTQVSGNFGTKNSSGQIVTEGNSWSDYIS
                     QIDSISASIILDTENESYERRVTAKNLQDPEDKTPELTIGEAIEKAFGATKKDGLLYF
                     NDIPIDESCVELIFDDNTANKIKDSLKTLSDKKIYNVKLERGMNILIKTPTYFTNFDD
                     YNNYPSTWSNVNTTNQDGLQGSANKLNGETKIKIPMSELKPYKRYVFSGYSKDPLTSN
                     SIIVKIKAKEEKTDYLVPEQGYTKFSYEFETTEKDSSNIEITLIGSGTTYLDNLSITE
                     LNSTPEILDEPEVKIPTDQEIMDAHKIYFADLNFNPSTGNTYINGMYFAPTQTNKEAL
                     DYIQKYRVEATLQYSGFKDIGTKDKEMRNYLGDPNQPKTNYVNLRSYFTGGENIMTYK
                     KLRIYAITPDDRELLVLSVD"
     gene            complement(6962..8353)
                     /gene="cdtA"
                     /locus_tag="PC466_003255"
     CDS             complement(6962..8353)
                     /gene="cdtA"
                     /locus_tag="PC466_003255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylating binary toxin enzymatic subunit
                     CdtA"
                     /protein_id="HDF2770611.1"
                     /translation="MKKFRKHKRISNCISILLILYLTLGGLLPNNIYAQDLQSYSEKV
                     CNTTYKAPIERPEDFLKDKEKAKEWERKEAERIEQKLERSEKEALESYKKDSVEISKY
                     SQTRNYFYDYQIEANSREKEYKELRNAISKNKIDKPMYVYYFESPEKFAFNKVIRTEN
                     QNEISLEKFNEFKETIQNKLFKQDGFKDISLYEPGKGDEKPTPLLMHLKLPRNTGMLP
                     YTNTNNVSTLIEQGYSIKIDKIVRIVIDGKHYIKAEASVVSSLDFKDDVSKGDSWGKA
                     NYNDWSNKLTPNELADVNDYMRGGYTAINNYLISNGPVNNPNPELDSKITNIENALKR
                     EPIPTNLTVYRRSGPQEFGLTLTSPEYDFNKLENIDAFKSKWEGQALSYPNFISTSIG
                     SVNMSAFAKRKIVLRITIPKGSPGAYLSAIPGYAGEYEVLLNHGSKFKINKIDSYKDG
                     TITKLIVDATLIP"
     gene            complement(8743..9489)
                     /gene="cdtR"
                     /locus_tag="PC466_003256"
     CDS             complement(8743..9489)
                     /gene="cdtR"
                     /locus_tag="PC466_003256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family response regulator CdtR"
                     /protein_id="HDF2770612.1"
                     /translation="MDILIFDNDVCFGIKLKEKINNILIKEGFDNDVIRLYYNANLLL
                     KELTEKNKVKIYFIVVDAKYKISNELCDGLWIAQKIRESDYISPIIFLTNHIEMILGI
                     FDYRLEVMDFILKHDMEIAESKIKACIKIAHKRYVKEKNYRSNFFTIYSDSSLWKISF
                     DEVIYFETSAIPHKIKLVTTSRIFEFYKSLRSLSDLDACFIRVHKSFVVNKYHIVSLD
                     LKKNNIKMSNGHICRISNTYRNILKNIIKT"
BASE COUNT         3306 a         1269 c         1389 g         3650 t
ORIGIN      
        1 ttattattaa aactgttttt gaatatgcaa atattttgaa aaatatcagt ttaataataa
       61 tgaatctatt ttattaattt tgaaattaaa tttaaaataa ttaatagaga ggggaaatga
      121 aattaggatg gaaaagaaaa aaataggcct atggagtttg gtatttatga atgtatcagc
      181 tttatatggt ataagatgga tagctaagtc tacagcatca agctttggtt taggattagg
      241 tgcaatacct atgtggttat tattctcatt tatatacttt gtaccaggag ctttaatttg
      301 cgctgaatta gcttctacat atcaaaaggg tgatggaggt ctttacgatt gggttaagga
      361 agcctttgga gaaaagtatg gatttttagt ttcttggtta aactggacag ctaaaatatt
      421 ttggtattct tcatttttaa ctttcttagc agtaaatgtt tcttatacaa taggaaatcc
      481 agctcttgct gataataaga tgtttgtact tatattatct ttaataatat tctgggcatt
      541 atctcttata gcaactaaag gaataagttt tacaaaaata tttactaata caggtgcatt
      601 aggttcaaca ataccaagtg ctatacttat aatattttca tttgtagcag tatttatgtt
      661 gaaaaaacat gatatagctt ctacatatac aatagcttca atgactccaa aacttaatat
      721 ggatgcattt gttgctatat cagctataat gtttggttta gcaggagcag agactgctgc
      781 taacttcata acagaaatag ataagcctga aaagaacttc cctaaggcaa tattaatatc
      841 agctggaata gtagcttcat tatatgtatt aggttcaatt gcaataacaa tgataatacc
      901 accagaccaa attactgctt ctaaaggtgt attagatgca ctttctgctg tttgtacgtc
      961 tttaggaatt ggttcttggt tggttcaatt aatagctttt ggtatagctt tctcagtatt
     1021 aggagcaata gttctttata tagcatcacc aataaaaatg ttatttggta gtgttaaaaa
     1081 aggaatattt ccagatagtt tggtagaggt aaatgaacac aagatacctt ctaaagcagt
     1141 tatacttcaa gcaataatag ttactataat actattggtg actacattaa tgccttctgt
     1201 tgatgctata tacaatgttc ttgtaactat gacagcatta actgcattat tcccatatgt
     1261 attattatat gcttcttata ttaaactaag aaaagagaga ccagatgaaa ttagacctta
     1321 tactatggca aaatcaacaa gtacttgcct aggtttagca aaaatggttt tagttgtaac
     1381 tgtagttggt atattattat ctgcagcacc agttatgccg acatttgctg aaaatgttat
     1441 atatgagata gagatgattg gtggaggtct tctagttata ttatctggtc tatggttatg
     1501 gaatagatat gaaaagaaaa cagctaaata aaatgtattt taaaaatttc ttttggatat
     1561 tataatatat agttgacaat ttatagtgta aggaatatta taaaataaag aaattaataa
     1621 attaaatcct gagataagaa atagtaaata aatatatttt tgcacagaga attaaggatg
     1681 ctgagaactt aataaaaagt atttattgaa tgggtctttg aggagtaaaa tgaaatgtaa
     1741 tttaagatta cagagtattt gatatcgtgt atgcacgtta tagcatatat taagatatat
     1801 atattcagtt ttgagtgtat ataaatttag gtggtaccac ggaaaatata tccgtcctat
     1861 tgatttagga cggatttttt aatatagaaa atttaggagg aaaaatgaac gtaataggaa
     1921 ttataggtgc aatggatgaa gaagttagta ttttagttga tttaatggat attagagaga
     1981 ctataaaaaa agctagctta gaattttata agggaatttt gaaaggtaag aatgtagtgt
     2041 tagtaaagtg tggtataggt aaggttaact ctgctctttg tgcccagata ctaataagcg
     2101 aatttaaggt tgatgctatt gttaatacag gtgttgcagg agctttaaat gaaaaacttg
     2161 atgttaatga tatagtaata tcaactgatg ctatacagta tgatgtagat actacagcat
     2221 ttggagaccc taagggagtt ataccaagaa tgaagacttc tgtatttaaa gcagatgaaa
     2281 gacttataga tgctgcttac aaatcttctg tggaagaagt aaagactcat aaagtattaa
     2341 aaggaagagt agttacagga gataaattta taaattctaa agaattaaaa gaagaattag
     2401 taaatgattt tggtggatat tgtggagaaa tggaaggtgg agctatagct catgtatgct
     2461 atttaaataa tactccattc gtaataataa gagcaatgtc tgataaggca gatggaagtg
     2521 ctgatgttac ttatgatgta tttgtacatg atgctgccaa taactctaaa gacatagttt
     2581 taaatatgtt aaaatcaata taaatatata aggaggtaca aaaaaatgag tgaaaaaaaa
     2641 gttatattta gtggagcaca gccatcaggc aaaatgactt taggaaatta tttaggagct
     2701 ataaaaaact ggactgaact tcaagataat tatgattgct attatagtat agttgattta
     2761 catgcaataa cagtacctca ggaccctaaa gttttaagag cgaatgctat agaattactt
     2821 gctcaatata tagcttgtgg attagaccca gaaaaaaata ctatatttat acaatcacat
     2881 gtcaaagagc atgttgaact tatgtgggta ttgaatacta tgacttatat gggtgaatta
     2941 agtagaatga ctcaattcaa agataaatca caaaagagtg aagcaaatct aaatgcaggt
     3001 ttattcacat atccagttct tatggccgct gacatattgt tgtatcaaac tgacctagtt
     3061 ccagttggag atgaccaaaa acaacattta gaattagctc gtgatttagc aaataggttt
     3121 aataatagat tttcacctac ttttgtagtt ccagaaggat actacccaaa aggtggagca
     3181 agagtgatga gtttgcaaga gccaactaaa aaaatgagta aatccgattc aaatgaaaat
     3241 gcatttatac tattagcaga tgattcagat tctataaaga gaaagataaa aagaagtgtt
     3301 actgattctt taggtgttgt aaaatacaat gatgaacaac caggtattaa aaatctaatt
     3361 gatatatatt ctaatttaag taaaaagagt gtagaagaga ttgtaaacat gtatgaagga
     3421 aagggttatg gcatatttaa agaagatgtg gctgaagtag tatcagaagc tttaagacct
     3481 ataagagaaa aatatgttga ccttcttaat aataaagatt atttagaaaa aatatatagt
     3541 atgggagcag aaaaagccga aaaacaagct agaaaaactc ttagaaaagt ttataaaaaa
     3601 gttggattta tagagagaag atactaatta ttagctatct ttacttgata aataaatttt
     3661 aaagttatta aaaaggtata tgatatgaaa gagagagtct caaagtgaac ttttgttcat
     3721 gagacactct tttttgtatg aaataaaata tattttaatc acttcaacaa tgaaaaagag
     3781 gattatctct attttgagac agcatctttt gataataaaa aaagatgagc ttttgctcat
     3841 ctcaaagggg ttagattatt cttactttgg ggaaagtaga ataaaggtaa aagttaactg
     3901 atgtcaactt tgtctttttt gcatatcact actgagcata aaaaaatcag aaaaccatag
     3961 ccttctgaaa caacttctaa catacattgt attttatacc caatatgtaa tttatgagtt
     4021 aattttaact cttataatgg aaattgtcaa taatatatca aaaaaatatt ttttaaattt
     4081 atataattaa atgaatttat gtttatatat aggtgatatg atacagataa ttatctttat
     4141 aatacaatat agttctaaaa aagaatatgt tagaagaaga gaatatttaa ataaaaaata
     4201 ccttataaag ttaatttttt agtactttat aaggtaaata tatattgtat tgtggggaca
     4261 aatttaaatc atttgatact aatcaacact aagaactaat aactctctat cgtctggagt
     4321 aattgcatat attcttaatt tcttgtatgt cataatattt tctccacctg taaaataact
     4381 cctaagatta acataattag ttttaggctg atttggatct cctaaataat tacgcatttc
     4441 tttatcttta gttccaatat ctttaaatcc agaatattgt aaagtagctt caactctata
     4501 tttttggata taatcgagag cttctttatt agtttgtgtt ggtgcaaaat acataccatt
     4561 tatataagta tttcctgtac ttggattaaa atttaaatct gcaaaatata ttttatgtgc
     4621 atccattatt tcttggtcag ttggaatttt aacttctggt tcatcaagta tttcaggagt
     4681 actatttagc tctgtaatag ataagttatc taagtatgtt gtaccactac caattaatgt
     4741 tatctctata ttagaagaat ctttttcagt agtttcaaat tcataactaa attttgtata
     4801 tccttgttct ggtaccaaat aatccgtttt ctcttctttt gcttttatct ttacaattat
     4861 tgaattagat gttaaaggat cctttgaata tccactaaaa acataacgtt tataaggttt
     4921 tagctcagac atagggattt taatcttcgt ctcaccattt aatttatttg ctgagccttg
     4981 taaaccatct tgattcgtag tattgacatt actccatgta ctagggtaat tattataatc
     5041 atcaaaatta gtaaagtaag ttggtgtttt tataagtata ttcattcctc tttcaagttt
     5101 aacattatat atctttttat cagacaaagt ttttaaacta tctttaatct tattggctgt
     5161 attatcatca aatatgagtt caacacaact ttcatctatt ggtatatcat taaaatataa
     5221 caaaccatct tttttagtag cgccaaaagc tttttcaatt gcttctccaa ttgtaagttc
     5281 aggtgtttta tcttctggat cctgtaaatt tttagcagta actcttcttt cgtaagattc
     5341 attctctgta tctaatataa tagatgcaga aatactgtca atttgactta tatagtctga
     5401 ccaactattt ccttctgtta ctatttgtcc agaactattt tttgtaccaa aatttccact
     5461 tacttgtgtt gtttctaatt taatttgctt tccagcatct aattttttta attgatcata
     5521 atttatagga atcagtctag agctaaattg atccattgtg ttaagagcta gaggtgaaag
     5581 cccttttttg ggataagtat ctccaggaga tagattattg ccaatttgat tttcttgtgc
     5641 tttgatagtt gataatgtat ctccatctaa cactaaattt gttgttggtg tcactttgta
     5701 cataggtgca gtacctgtgt tgtaatatct aacatttgca tttatatatg cagattctcc
     5761 tttgtttata cttaatccag tattccatga ttctccatta ctatcttgaa cagcagttga
     5821 attatctgtt gtatgggaat aatttgtagt tacattagct gtgaatccat tttgatatcc
     5881 tacattaaca gacacaccag ctgtattaga ttcagtttta ctgttagtag tagctctgga
     5941 aacagtttta ccttgatcag tagaggcatg ttcatttgta gatataatta atttttccat
     6001 acctactcca acaattggat atgctgcaac taacggatct cttgcttcag tctttatagc
     6061 cttgtcaaaa gaacctgaag ctttttcata atctgtatat ggatctccag cagtatttga
     6121 ctctaaataa tttgatacat atttcttata gccttgttct gcaaaactat cttcccactt
     6181 aactgcaatt aagtccttaa tagtatatcc atttcgttca tatgaatctg gtatattatc
     6241 attatctgta tccaaatctt cgtcttccca atcagacatc aactttgggt caaagaaatt
     6301 gttatttggg ataaatggat catctttttc tatattagaa taatctctta agaataaatt
     6361 ttcttctggt ataattttct tcataccatc taattcccaa taaagattag gtgatgataa
     6421 attatctatt gaacctaaat ttttatcttg tagctctatt ctaactttat attctttacc
     6481 ctttttcata ttaactttaa gtgtatttga tatagtactc tcagtattta cttgcattaa
     6541 gacatcatct ctatcagttg ataatgtata ttcaccatcc ttagaaggaa ttattcttcc
     6601 tgtccatcgt atagatttta catctgattt gtctttatcc agaagtttat ctactttctt
     6661 ttcttcaaat tttaaattac catcttttat gggtgccatt aattttaaat ctttaaagtg
     6721 ctcatctgtg aaataatatc ccattaatcc attgtttggg agtatatctt catttacaat
     6781 ttcttttttc ttattagaat gattacttgt actagtttga gcatatacag gatatactag
     6841 tgcttgacta actatagctg taagtgttaa aaaacttaat acctttttat tcctcatttg
     6901 tattttcatt gtttctcctc cttaaatttg aaaaatatta aattatttat gtgaaaaaat
     6961 attaaggtat caatgttgca tcaacaatta attttgttat agtaccatct ttgtaagaat
     7021 caattttatt gattttaaat ttgcttccat gatttaaaag cacttcatat tcacctgcat
     7081 aacctggaat agctgataga taagctccag gagaaccttt aggtatagtt atacgtagta
     7141 ctatttttct tttagcaaat gcactcatat tcacactacc aatactagta ctaataaagt
     7201 ttggataaga cagtgcttgt ccttcccatt ttgatttaaa agcatctata ttttctagtt
     7261 tgttaaaatc atattcaggg gaagtaagag ttaaaccaaa ttcttgagga ccagatcttc
     7321 tatatacagt taaattagtt ggaataggtt cacgttttaa tgcattttca atgtttgtga
     7381 ttttagaatc taattctggg ttaggattat ttactggacc atttgatatt aaataattat
     7441 taattgcagt atatcctcca cgcatataat catttacatc agcaagttca ttaggtgtta
     7501 atttattact ccaatcatta taatttgctt taccccaaga atccccctta cttacatcat
     7561 ctttaaaatc aagactactt acaacagatg cttctgcttt aatatagtgc ttcccatcta
     7621 taactatacg aacaatttta tctattttta tactatatcc ttgctctatt aatgtactta
     7681 cattgttagt atttgtatat ggtaacatac cagtatttct aggtaatttt aagtgcataa
     7741 gtaatggtgt aggtttttca tcaccttttc caggttcata taaagaaata tctttaaatc
     7801 catcttgctt aaataatttg ttttgtatag tttctttaaa ctcattaaat ttttctaatg
     7861 aaatttcgtt ttgattttct gttcttatta ctttattaaa tgcaaatttt tctggagatt
     7921 caaaataata gacatacata ggtttatcta ttttattttt tgatatagca tttcgaagtt
     7981 ctttatattc tttttctcga gaatttgctt ctatttgata atcataaaaa taatttcttg
     8041 tctgagaata tttacttatt tctacagaat cttttttata tgattctaat gcttcttttt
     8101 cagatctttc aagtttttgc tctattcttt ctgcttcttt tctttcccat tctttagcct
     8161 tttctttatc tttaagaaaa tcttctggtc tttctatagg agccttgtaa gtagtattgc
     8221 aaactttttc actatagctt tgtaagtctt gtgcataaat gttattaggt aacaaaccac
     8281 ctaaagttag atataatatc aacaatatag atatacaatt actaatcctt ttatgtttcc
     8341 taaatttttt catttattct ccctcccaat attagtttaa ttaactcttg aactttaatt
     8401 tatttagatt atataatcta aataagaatt ttttatataa atttcataaa atatgtaact
     8461 atatatcata aaaatatgta tttatatgat atgtcagtac aaaataacaa ctgaatattt
     8521 taaagagact atttcatact tttatgattt aatgagctat cttgttgaat cataatctag
     8581 gaacaatggt tgcaatgtct aatagaaatt gtatatgata tagtcattat gtgttttttc
     8641 acaaaacgat tattatatag aggattctta ggaactactt tttttgtata aaaaaagaga
     8701 tggttcaaat tcttatcttg agacatctct tttttctatt tattatgttt taataatgtt
     8761 ctttaaaata tttctatatg tattagatat acgacatata tggccattac tcattttaat
     8821 attatttttc tttaggtcga gagaaacaat atgatattta ttaactacaa aagatttatg
     8881 tacacgaata aagcatgcat ctaaatctga taaagacctt aaacttttat agaattcaaa
     8941 tattcttgaa gtagtcacta attttatttt atgtggaata gcgcttgttt caaaatatat
     9001 aacttcatca aatgaaattt tccatagtga ggaatctgag tagatagtaa aaaaattaga
     9061 gcgataattt ttttctttaa cgtatctttt atgagcaatt ttaatacaag cttttatttt
     9121 actttcagca atttccatat catgttttaa tataaagtcc ataacttcta acctataatc
     9181 gaagatccct aaaatcattt ctatatgatt tgtaagaaat atgattggac taatataatc
     9241 tgattctcta attttttgtg ctatccataa tccatcacat aattcattac ttatcttgta
     9301 ttttgcatct acaactataa aatatatttt tactttattt ttttcagtaa gttcttttaa
     9361 taacaaattt gcattataat ataatcttat aacatcgtta tcaaaacctt cttttattaa
     9421 aatattattt attttttctt ttagttttat tccaaaacaa acatcattat caaaaattaa
     9481 tatatccact aaataccctc ctataaaaaa ttcaaaagta aaaaaactaa aagtatttta
     9541 taaaaaatac gtaaaataac actaggagat aaataaaatt aaggatagtt agaattaagg
     9601 tatatttatg cttg
//
LOCUS       DAMJYN010000113         9558 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.118, whole genome shotgun sequence.
ACCESSION   DAMJYN010000113 DAMJYN010000000
VERSION     DAMJYN010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9558)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9558)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9558
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.118"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(138..791)
                     /locus_tag="PC466_003257"
     CDS             complement(138..791)
                     /locus_tag="PC466_003257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2770613.1"
                     /translation="MKVDPLTTQVYDYISKKIQNGEYEANQRITESEICKSIGVSRTP
                     AREALTRLAGENLLEKIPNKGFVVKEFQEKEKLDTYSVIGVLDALAGSSALQNLTESD
                     LVKMEELTEMMAVSIKYKNYNSYLKLSNEFHDIYITKSDNQVLVNLLNSLRYNFMSKS
                     YTSDNEDELYKMLTYSNNQHIEVVKFMRENDLENVERVLREHWKTIPIAEMKKEKLL"
     gene            complement(1036..2901)
                     /locus_tag="PC466_003258"
     CDS             complement(1036..2901)
                     /locus_tag="PC466_003258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase C-terminal domain-containing
                     protein"
                     /protein_id="HDF2770614.1"
                     /translation="MQSVIEYNSWDKNFKAPFGALKFDEELTICVKVNEGYNIKSISL
                     EINREEEMRTITLNEELDNDKLGKCFCGKIEKFDGTGVYFYYFKVDVEMDGQIKTLFY
                     GKNRDNGYSCEYNYSDINKYQITVYKDFKVPTWYKEGILYHIFVDRFNNGNRSGKVDN
                     PKKNSFIYGNWEDIPMYIKDSQGDVIRWDFHGGNLRGIINKLGYLKKLGVSILYLSPI
                     FEASSNHKYDTGDYKKIDPMFGDEDTFKELIDKAKEKGISIVLDGVFSHTGADSKYFN
                     MYGNYNSLGAYQSKESPYYSWYMFEEFPQKYKSWWDVKTLPNINELEHSYMDYIIYDN
                     DSVINKWVNMGIKGWRLDVADELPTKFIRELKKELKKADDDSILIGEVWEDASNKISY
                     GQRRSYLLGEELDSVMGYPFRNNMFSFLKGEINSYELCNRYMQIKENYPKESFRSNLN
                     LIGTHDVTRAKTELNDDVDLVKLAVAIQMTFEGVPYIYYGDEAGLCGGVDPDNRRTYP
                     WKNEDEDMLNFYRDVIKIRNKNKLLSSGNTEFIYTNNDSVFSFIRVDENNDRMLILVN
                     RSENVESISLCIESSFIEEIPIKYSLKNANSTIQIENNELKVDLDSKSFRIFRVN"
     gene            complement(2906..5326)
                     /locus_tag="PC466_003259"
     CDS             complement(2906..5326)
                     /locus_tag="PC466_003259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan phosphorylase"
                     /protein_id="HDF2770615.1"
                     /translation="MVTISKKKFKQKFEVKMYSLYAQSIKEATDEQLLNVLCSLLKDE
                     IAKKWVATKLDKKKEVYYFSLEFLIGRQLKSNLLNLNIEEEVREGLSELGINLDDLIE
                     AEVDPALGNGGLGRLAACFLDSMASLNISGQGYGIRYKYGLFEQKFVNGYQVEVPDNW
                     LTEGRYAWETVRPNEATMVKFGGEVELIKEGSHLKVIHKNYLPVMAMPYDIPIIGYQN
                     QCINTLRLFKSEIPKRDFGELTSNALNYSGSYEEALKHKYYTEEISQVLYPDDSNYAG
                     KLLRLKQEYFFVSAGIQDIIRKYKKNKLNIDNLFDKVAIHINDTHPTLCIPELMRILL
                     DEENLSWDEAWEITKKTVSYTNHTIMSEAMEKWPVSMMKELLPRIYMIIEEINRRYVE
                     ELNNKGYEQDRIKRMSIIDCDNINMANLCIVTSHSVNGVAKLHTHILETEVLKDFYQD
                     EPNKFNNKTNGIAHRRWLISSNPQLSNLITDLIGDSWKKDTLQLKNIEKFKNDSSVLQ
                     RLDDIKYNNKANLAKFIKDKYDLNVDPSSIFDVQVKRLHAYKRQLLNIFNVLHMYHEL
                     LDNPNLNLDPRTFIFGAKAAPGYYLAKCIIKFINSVASTINNDVRVKDKLKVVFLENY
                     GVSLAEIIIPAANVSEQISTTTKEASGTSNMKFMMNGAITLATLDGANVEICEQVGKE
                     NMFLFGLSAEQVLNYNKYGGYSSLDLYHSNMDIKRVVDDLINGFIPNLGEEGRSIYNS
                     LTTYNDEYFVLRDFENYGQAQADINRLYRDKEKWNKMSLVNIANSGFFSSDRTISEYA
                     KDIWFKRV"
     gene            complement(5340..6782)
                     /gene="glgA"
                     /locus_tag="PC466_003260"
     CDS             complement(5340..6782)
                     /gene="glgA"
                     /locus_tag="PC466_003260"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011053260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HDF2770616.1"
                     /translation="MKVFYVTAECWPFAKTGGLGDVSYALPKELKKEGVDVRVIMPKY
                     STIPSYLKDQLKEIAVFSVRVGWRNQYCGLLEMELDGVKFYFIDNEFYFRREDERKSI
                     YGYGDDAERYTFFTDAVLEAISRIDFYPDVIHINDWHTGMLPLILKERYATLEGYKNI
                     KTMYTIHNLQYQGVFDKHVLYDILDLPQKYFDNRDIEYYGSINFMKAGINFADKIITV
                     SPTYANEIQTSFYGEQLDGLLRKESGKLKGILNGIDYDLNDPAKDKDIFVHYDVDSID
                     KKVENKLRLQDILGLKKDSSIPLIGIVSRLVSQKGFDLIAYMMPELMREDLQIVVLGT
                     GEHQYQSMFNYYDSNFSDKVSARITFNASLAQQIYAASDMFLMPSLFEPCGIGQMLAM
                     RYGSLPIVRETGGLRDTVTPYNKFTGEGNGFSFKNYNAHEMFFCLKNAIKVFKDKEKW
                     IKLVENAMKTDNSWKKSAKEYIETYRDICD"
     gene            complement(6811..7941)
                     /gene="glgD"
                     /locus_tag="PC466_003261"
     CDS             complement(6811..7941)
                     /gene="glgD"
                     /locus_tag="PC466_003261"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HDF2770617.1"
                     /translation="MRNECLGIINLNKKGDPAINKLNYGRPIASTPIAGRYRIIDFAL
                     SNMINSGITKVGIFAKEKYRSLTDHIGSGKDWDLSRKKGGLSIFSPENTKYRNTYSHR
                     EGDIYTILANLDYIEKSEEEYILIAPSYMLCNLNYSQALEYHKKSHNDITIIYKNVNN
                     ANKDFAGNLTLNLDSNNRVINVGNNLGKFPRANICMETYIMKREDFVECIYNIVNKGS
                     YCYLEEFIIEEAENMKIGAYEYTGYLKCVNSVESYFEMSKDLLNLEVADELLYSERKI
                     FTKEKNESPTIYTDSAKVENSFIASGCLIEGTVKDSIIFRKVNVEKGTVIENSIVMQN
                     CVIKSNAKLYNAILDKNTSVSNGKELRGDEKYPLVVEKNTNI"
     gene            complement(7943..9103)
                     /locus_tag="PC466_003262"
     CDS             complement(7943..9103)
                     /locus_tag="PC466_003262"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HDF2770618.1"
                     /translation="MKKEMLAMILAGGQGSRLGVFTKRIAKPAVSFGGKYRIIDFVLS
                     NCSNSGIDTVGVLTQYRPLILNSHIGMGSHWDLDRINGGVYVLQPFMNEKEGNWYNGT
                     AHAIYQNMDFVDTYNPEYVLILSGDHIYKMDYSKMLKFHKEKRSKATIAVIEVPWDEA
                     SRFGIMNTNEDSSIYEFEEKPSEPKSNLASMGVYIFDWKMLRNYFKEAEKNPEINYDD
                     FGKNLIPKMLEDNVGMYAYPFKGYWRDVGTIQSLWDANMDIIKSPETLDLADPKWKIY
                     TNTMAMPPQYIGKNANVHRSMIADGCRILGEVGNSVLSHGVVVGKGSKVIDSVIMPNV
                     VIGENVTIEKAMIGECATINDNVQIKNVNNEINVVSEYENIEPRCVLIEGGL"
BASE COUNT         3037 a         1739 c          925 g         3857 t
ORIGIN      
        1 tatatgttaa tttaaatata ttattctatc gtagtgcctt agagttttta tttgtattta
       61 aagttaaatt tattcttgtt tttcctttaa tatttaatag taaaataaca aaattataaa
      121 aaaaataaag agaaacttta taaaagcttc tcttttttca tctctgctat aggtatcgtt
      181 ttccaatgtt ctctcaaaac tctttcaaca ttttctaaat cattctccct cataaatttt
      241 actacttcaa tatgttgatt attgctgtat gtcaacattt tatataactc atcttcatta
      301 tcactagtat atgactttga cataaaatta tatcttaaag agttcaatag atttactaac
      361 acctgattat ctgatttagt tatgtatata tcgtgaaatt cattacttaa ttttaaatag
      421 ctattgtaat ttttatactt tatagagacc gccatcattt ctgttaattc ttccattttt
      481 actaggtctg attcagttaa attttgtaat gctgaagaac cggctaacgc atccaatact
      541 ccaattacgg aataggtgtc taatttctcc ttttcctgaa attcttttac tacaaatccc
      601 ttattaggta ttttttctag taaattttca cctgctaacc tagttaatgc ttctctagct
      661 ggtgttctac taactccgat agatttacaa atctcagatt cagtaattct ctgattagct
      721 tcatactctc cattttggat tttctttgat atatagtcat atacttgagt tgtaagtgga
      781 tctaccttca taagacgttc ctccatatta agattataaa agttaaatct ccctacaact
      841 ttggtagaga gttcagtttt atcttactaa tttatataat atcacaatta tgatattttt
      901 tatacttctt tgtaatattt tgaaacacta aaattcttat gataatttat acaaaaaaag
      961 tagaaaaagt tttgataaaa caaaactctt tctacattca ccttattttc tatttatttt
     1021 tctaaaaaaa gatatttaat ttactctaaa aattctaaat gatttagagt ctaaatctac
     1081 tttcaactca ttattttcaa tttgtatagt actatttgca tttttaagac tatactttat
     1141 aggtatttcc tcaataaaac tactctctat acataatgat atactttcca cattttcact
     1201 tctatttact aaaattaaca ttctatcatt attttcatca actctaataa aagaaaatac
     1261 agaatcatta ttagtatata taaattctgt atttccagaa cttaaaagtt tattcttatt
     1321 tctaattttt ataacatctc tataaaaatt aagcatatct tcgtcttcat ttttccatgg
     1381 ataagttctt ctattatctg ggtcaacacc tccacaaaga cctgcttcat ctccataata
     1441 tatatatggt actccttcaa atgtcatctg tatagctaca gcaagcttca ctaaatctac
     1501 atcatcattt aattccgttt tagctcttgt aacatcatgt gttccaatta aatttaaatt
     1561 agacctaaat gattcttttg gataattttc tttaatctgc atatatctat tacaaagttc
     1621 atatgaatta atttctcctt ttaagaaaga aaacatgtta tttctaaaag gataacccat
     1681 aacagaatct aattcttcac ctaataaata acttcttctc tgaccatagc taatcttatt
     1741 tgatgcatct tcccatactt cacctataag aattgagtca tcatctgcct tttttaattc
     1801 cttttttaac tctcttataa acttagttgg taattcgtct gcaacatcta gtctccagcc
     1861 cttaataccc atatttaccc atttatttat aacgctatca ttgtcatata ttatataatc
     1921 catatagcta tgttctaatt catttatatt tggcaatgtc ttaacatccc accaactttt
     1981 atacttttga ggaaattctt caaacatata ccatgaataa tatggagatt ctttagattg
     2041 atatgcccct aaactattat agtttccata catattaaaa tatttactat ctgctccagt
     2101 atgactaaaa actccatcta atactattga tatacctttt tcttttgctt tatcaataag
     2161 ttctttaaat gtatcttcat ccccaaacat tgggtcaatt tttttatagt cacctgtgtc
     2221 atatttatga ttactagaag cttcaaatat agggcttaga tatagtatac ttacacctaa
     2281 tttttttaaa tatccaagtt tattgattat ccctcttaaa tttccaccat ggaaatccca
     2341 tcttataaca tccccttgac tatcctttat gtacataggt atatcttccc aatttccata
     2401 tatgaaacta ttttttttag gattatcaac cttaccacta cgatttccat tattgaatct
     2461 atctacaaat atatgataaa gtattccttc tttgtaccat gttggtactt taaaatcttt
     2521 gtaaacagtg atttgatatt tattaatatc actataatta tattcacaag aatatccatt
     2581 atctctgttt tttccataaa ataaagtctt tatctgacca tccatttcaa catcaacttt
     2641 aaagtaataa aaataaacac ctgtaccatc aaacttttca atcttaccac aaaagcactt
     2701 tccaagttta tcattatcta attcttcatt taaagttatt gttctcattt cttcttctct
     2761 atttatttct agggaaatag acttgatatt gtatccctca tttactttaa cacaaatggt
     2821 caattcctca tcaaatttta aagctccaaa cggagcctta aaatttttat cccaagagtt
     2881 atattctatt acactttgca tttaatcaca cccttttaaa ccaaatgtct tttgcatact
     2941 cagaaattgt tctatcagaa gaaaaaaatc cagagttagc tatattaact aaagacattt
     3001 tattccattt ttctttatct ctatataacc tgtttatatc tgcttgagct tgaccataat
     3061 tttcaaaatc tctcaataca aaatactcat cattgtaagt agtgagtgaa ttataaatac
     3121 ttcttccttc ttcgccaaga ttaggaataa atccatttat taaatcatct accacccttt
     3181 ttatatccat attagaatga tataagtcaa gtgaagaata tccaccatat ttattataat
     3241 ttagtacttg ttctgcacta agtccaaata aaaacatatt ttctttacca acctgttcac
     3301 atatctctac atttgcgccg tcaagtgtag ccaaagttat agcaccattc atcataaact
     3361 tcatattact tgttccagat gcttccttag ttgtagttga aatttgctca ctaacatttg
     3421 ctgctggtat tattatttct gctaatgata ctccataatt ctctaaaaat actactttta
     3481 acttgtcctt tactctaaca tcattattta tagtacttgc aacagaattt ataaatttaa
     3541 ttatacattt agccaaataa tatcctggtg ctgcttttgc accaaatata aaagttcttg
     3601 ggtcaagatt caaattagga ttatcaagta attcatgata catatgaagt acattaaata
     3661 tattcagtaa ctgtctttta tacgcatgca atctcttaac ttgaacatca aatatcgaac
     3721 ttgggtctac atttaaatcg tatttatctt ttataaactt tgctagattt gctttattat
     3781 tgtattttat atcatcaagt ctttgtaaaa cagaggaatc atttttaaat ttttcaatat
     3841 tttttaattg taaggtatcc ttcttccatg aatcaccaat taaatctgta attaaattgc
     3901 taagttgagg atttgaactt ataagccatc gcctatgtgc aattccatta gtcttattat
     3961 taaatttatt tggttcatct tgatagaaat cttttaatac ctctgtttca agaatatgag
     4021 tatgaagctt agcaactcca tttacactat gacttgtgac aatacataag tttgccatat
     4081 tgatattgtc acagtctatt atactcattc tttttattct atcctgctca tatcctttat
     4141 tatttaattc ctctacatat cttctattta tttcttctat tatcatataa attcttggta
     4201 atagttcttt catcatactt acaggccatt tttccattgc ttctgacatt atagtatgat
     4261 tagtatagga cactgttttt ttagttattt cccatgcttc atcccaagat aaattttctt
     4321 catcaagcaa aattctcata agttctggta tgcataaggt aggatgtgta tcatttatat
     4381 gaattgctac cttatcgaat aaattatcaa tatttaattt gttcttttta tattttctta
     4441 ttatatcttg tatccctgca cttacaaaaa agtattcttg tttcaacctc aacaacttac
     4501 ctgcatagtt tgaatcatca ggatataata cctgtgatat ttcctcagta taatacttat
     4561 gttttaaagc ctcttcatag ctaccagaat aatttagagc atttgaggta agttcaccaa
     4621 aatctctctt tggtatttca ctcttaaaca atcttaaagt atttatacat tggttttggt
     4681 atccgattat tggtatatca taaggcattg ccattacagg aaggtagttt ttatgaatta
     4741 cttttaaatg actaccttcc ttgattaatt ctacctcacc accaaacttc accattgttg
     4801 cttcatttgg tcttacagtt tcccatgcat atcgtccttc tgtaagccag ttatcaggca
     4861 cttctacctg ataaccattt acaaattttt gttcaaacag accatattta taccttattc
     4921 catatccttg accacttatg ttcaaagatg ccatagaatc taaaaagcaa gctgctaatc
     4981 taccaagtcc accatttcct aaggctgggt ctacttcagc ttcaattaaa tcatccaagt
     5041 tgattcctaa ttcagataaa ccttctctaa cttcttcttc aatatttaaa tttaataaat
     5101 tagattttaa ctgtctccct attaaaaatt ctaaactaaa ataataaact tcttttttct
     5161 tatctaactt tgtagcaacc catttttttg ctatctcatc tttcaataga ctacataata
     5221 catttaacaa ttgttcatca gtagcttcct tgatagattg tgcatataag ctatacattt
     5281 ttacttcaaa tttttgcttg aatttctttt tgcttattgt taccaaaaaa accactcctt
     5341 taatcacata tgtctctata tgtttctata tactccttag ctgatttttt ccaactatta
     5401 tctgttttca ttgcattttc aactaattta atccattttt ctttgtcctt aaatactttg
     5461 attgcatttt tcaaacagaa aaacatctca tgagcattgt aatttttaaa actaaatcca
     5521 ttgccttctc cagtaaattt attataaggt gttactgtat ctctaagccc tccagtctct
     5581 ctaactattg gtaaagaacc atatctcata gctaacattt gacctatacc acaaggctca
     5641 aataatgatg gcattaagaa catatcactt gcagcatata tctgttgagc caatgatgca
     5701 ttaaaagtaa ttctagctga tactttatct gaaaaattag aatcgtaata gttgaacatt
     5761 gattgatatt gatgttctcc agttcctaaa acgacaatct gtaaatcttc tctcataagt
     5821 tctggcatca tgtatgctat taaatcaaat cctttttgag aaactaatct cgaaactata
     5881 cctatcaacg gaatagatga atctttttta agtcccaata tatcttgtaa tctcaattta
     5941 ttttctactt ttttgtcaat tgagtctaca tcataatgaa caaatatatc tttatctttt
     6001 gcagggtcgt ttaaatcata atctatacca tttaatatac cttttaattt tcctgactct
     6061 tttctaagta atccatctaa ttgttcacca taaaaagatg tttgtatttc atttgcataa
     6121 gtaggactaa cagttataat tttatctgca aaatttatac cagctttcat aaaatttatt
     6181 gagccataat actctatatc tctattatca aagtattttt gtggtaagtc caatatatca
     6241 tataaaacat gcttatcaaa tacaccttga tattggagat tatgtatagt atacatagtt
     6301 tttatatttt tatacccctc aagggttgca tatctttctt ttagaattaa tggtaacatc
     6361 cctgtatgcc aatcatttat atgtattaca tctggataaa aatcaattct acttatagct
     6421 tctaaaactg catctgtaaa gaaagtatat ctttctgcat catctccata tccatagata
     6481 ctctttcttt catcttctct tctaaaataa aattcattat ctataaagta aaattttaca
     6541 ccatccaatt ccatttctaa aagaccacag tattgatttc tccatccaac acgtacacta
     6601 aacacagcta tttcttttag ttgatctttt aaataacttg gtatagttga atatttgggc
     6661 attattaccc ttacatctac accttctttt tttaattctt taggcaatgc ataagaaaca
     6721 tctcctaatc ctccagtttt tgcaaagggc caacactctg ctgttacata aaaaaccttc
     6781 attagtcatt cccccttcta aaaaatttat ttatatattt gtattctttt ccactacaag
     6841 aggatatttt tcatctcctc ttaattcttt cccatttgat acactcgtat ttttatctaa
     6901 tattgcatta tatagttttg catttgactt tattacacaa ttttgcatta ctattgagtt
     6961 ctctataact gttccttttt caacatttac ctttctaaat atgatactat cttttacagt
     7021 accttctatt aaacaaccag atgctataaa gctattttct actttagcac tatctgtata
     7081 aattgtaggt gattcattct tttcttttgt aaatatcttt ctttcagagt ataataattc
     7141 atctgcaact tctaaattta ataaatcttt gctcatttca aaatatgatt caacagaatt
     7201 tacacatttt agatatcctg tatattcata agctcctatt ttcatatttt ctgcttcttc
     7261 aataataaat tcttctaaat aacaataact gcctttattt acaatgttat atatacattc
     7321 aacaaaatct tcacgcttca taatatatgt ctccatacat atgtttgctc tagggaattt
     7381 gcctaaatta tttcctacat ttattaccct attgttacta tctaaattta gtgttaagtt
     7441 accagcaaaa tctttatttg cattatttac atttttatat attatagtta tatcattatg
     7501 agatttttta tggtattcca atgcttgaga ataatttaaa ttgcatagca tatagcttgg
     7561 agctattaaa atatattctt cttcactctt ttctatataa tctagattag ctaagatagt
     7621 atatatatca ccttctctat gtgagtaagt atttctatac ttagtgtttt ctggactaaa
     7681 aattgatagg ccaccttttt ttctacttaa atcccaatct ttaccactac ctatatggtc
     7741 tgtcaatgat ctgtattttt cttttgcgaa tattccaact ttagtgattc ctgaatttat
     7801 catattagat aaagcaaagt ctattattct atatcttcca gctattggtg tagatgctat
     7861 tggtcttcca tagttaagtt tgtttattgc tgggtctcct tttttgttta aatttattat
     7921 ccctaaacat tcatttctca tcttaaagac ctccttctat taatacgcat ctaggttcga
     7981 tattttcata ctcagaaact acatttattt cattatttac attctttatc tgaacattat
     8041 catttatagt tgcacactca cctatcatag ctttttctat agttacattt tcacctatta
     8101 caacatttgg cattattact gaatcaatta ctttacttcc tttaccaaca acaactccat
     8161 gtgataatac agagttgcct acttcaccta aaattctaca accatcagct atcattgatc
     8221 tatgaacatt tgcattttta cctatatatt gtggaggcat tgccatagta tttgtatata
     8281 tcttccattt agggtctgct aaatcaagtg tttctggaga ttttattata tccatattag
     8341 catcccatag actttgtata gttcctacat ctctccagta tcctttaaat ggataagcat
     8401 acattccaac attatcttct aacattttag gtattaaatt ttttccaaaa tcatcataat
     8461 ttatttctgg atttttttct gcttccttaa aataatttct caacattttc caatcaaata
     8521 tgtatactcc catagatgcc aaattgctct taggttcact tggtttttct tcaaattcat
     8581 agatacttga atcttcattt gtattcatta tcccaaatct tgaagcttca tcccaaggaa
     8641 cttcaatcac tgctattgta gctttagagc gtttttcctt atgaaatttt aacattttgc
     8701 tataatccat cttgtatata tggtcaccag ataatatcaa tacatattct ggattatagg
     8761 tatctacaaa gtccatattt tgatatatcg catgtgctgt accattatac caatttcctt
     8821 ctttttcatt cataaatggt tgtaaaacat agacaccacc atttattctg tccaaatccc
     8881 aatgacttcc catgcctata tgtgaattta atatcaacgg tctatattga gttaaaacac
     8941 ctacagtatc aataccagag tttgaacaat tacttaacac aaaatctata attctatact
     9001 tacctccaaa tgatacagct ggtttggcaa ttctttttgt aaaaacacct aatcttgaac
     9061 cttgccctcc tgccaaaatc atagctaaca tctctttttt catttaatga cactcccctc
     9121 atctagtaat taatatttat aattgcattt ttacttttat aaactttatc agtcaataaa
     9181 tgccgtgtat aaatgttgct taaataatac cttaataaaa ataaaataat atcaactata
     9241 caattgatat aatgtatacc ccataatgaa cttaccgacg tatacattat tttccataag
     9301 cactatagta tttattaata ttcaattatc ggttaaaaaa taatacaaat tttattttat
     9361 aaatataaaa acatttttta taaatccctt gtgtcatata aacatgctta ttttttaatt
     9421 tgttaaattc gtaatagcaa aatataatct aatatttgtt aaataattat ccaaagaaaa
     9481 tcaagtaatt attaatcaac tttatttttt aattgatact tctttgtcta taatttaaac
     9541 aaaaggatat aaactttt
//
LOCUS       DAMJYN010000114         9525 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.119, whole genome shotgun sequence.
ACCESSION   DAMJYN010000114 DAMJYN010000000
VERSION     DAMJYN010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9525)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9525)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9525
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.119"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            496..1701
                     /locus_tag="PC466_003263"
     CDS             496..1701
                     /locus_tag="PC466_003263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HDF2770619.1"
                     /translation="MSKKVLIMSASTGGGHNRAALAIKEELTSKTLDGEPIECEIIDS
                     LKLVNNTMDKIISRGYEKSAIYTPKAYGSVYRLSETNLLSKNEFKDNLLITFMAKKFK
                     KLIRSEKPDLIIGTHPFPMIALSTLKKNFNLHNNESNAYTEHFYKHYTNTINVPPLIS
                     VLTDYTTHSTWIQNEIDYYIVGHEYVKELLVFDGVGPSKIRTFGIPVEKSFLSHRDKD
                     IVLSELNLSPDKLTVLLMGGSFGAGNIKETLDELLDTDRDFQILVITGKNESLKEKIE
                     KKLMSRYHDKNVCVLGYTDKMNDILASIDVLVSKPGGLTTTEALLKDVPMIVPYYIPG
                     QEEENLDFLSNCGAALRTTKKYNLSILLKVLIDDPSRLEMLKRNVKSIRKSNSAQNIA
                     NLILNIISG"
     gene            complement(1772..1993)
                     /locus_tag="PC466_003264"
     CDS             complement(1772..1993)
                     /locus_tag="PC466_003264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770620.1"
                     /translation="MKPIMNLEEHNAMKEKRVKKMKSKDKPKYDDFEDISFSNKKKTK
                     KNVRNKNAEFRNNYKNYQYDYEEDFYEPI"
     gene            complement(2134..2733)
                     /gene="recR"
                     /locus_tag="PC466_003265"
     CDS             complement(2134..2733)
                     /gene="recR"
                     /locus_tag="PC466_003265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012634696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HDF2770621.1"
                     /translation="MQVYTGPITRLIEEFSKLPGVGRKTAQRLAFHIINMNTNDVEAL
                     SKAIIDAKREIRYCSICCNITDTDPCSMCSNKSRDSSVICVVEDPRDVAAMERTREFK
                     GQYHVLNGVISPMDGIGPDMLKIKELIQRLGNQEVKEIIMATNPTIEGEATAMYIARL
                     VKPMGIKVTRIAHGLPVGGDLEYADEVTISKALEGRREI"
     gene            complement(2746..3096)
                     /locus_tag="PC466_003266"
     CDS             complement(2746..3096)
                     /locus_tag="PC466_003266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HDF2770622.1"
                     /translation="MAKKGFGGGMMPGGGNMNNLLKQAQKMQENMQKAQQELESKEVE
                     ASVGGGAVTVKVNGKKEVIDITIKPEVVDPDDIEMLQDLVLSAVNQALRNIDDIQASQ
                     MSKVTGGMNIPGLF"
     gene            complement(3155..4792)
                     /gene="dnaX"
                     /locus_tag="PC466_003267"
     CDS             complement(3155..4792)
                     /gene="dnaX"
                     /locus_tag="PC466_003267"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HDF2770623.1"
                     /translation="MHKALYRAYRPQKFEDVIGQDHIIKTLKNQIYSDNIGHAYLFCG
                     TRGTGKTSTAKIFSRAVNCLNKINEEPCNECEICESVLKDNTMDVVEIDAASNNSVDD
                     IRELRESVKYSPANAKYKVYIIDEVHMLSQGAFNALLKTLEEPPSYVIFILATTEPHK
                     IPATILSRCQRYDFKRVTVKDMTLRMKKICEDEGIDIDDKALNLIARNSQGALRDALS
                     ILDQCMSFGESKIDYKDVVELMGSVNIEQLFELSQCIVEQDTKKSLEILNEFVLWGKD
                     IRNLINDLIDHFRNLMVCKVSSELDEIISLPEETIEQLKIQSKNIDINDLIRILNILS
                     ITQDDIKSSSNPRVLVEITIMKIAQPMFDESKEALIKRVENLEKMIELGNFKSEKIGN
                     NKEKEYEVDREIDVKQENVVYEDVKNEDVILIESSWKNILKQIKKDKKMPIYALLSEV
                     KSFNVYSNMLYVIFDDKFDFAKTRLSSQDTINYLEKTIRDVLNRSFNVKIVLTSEVKD
                     INLEVKEKKDIGEEILKNIVSEEILEIKYSIDENESK"
     gene            complement(4869..5133)
                     /gene="ffs"
                     /locus_tag="PC466_003268"
     ncRNA           complement(4869..5133)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="PC466_003268"
                     /product="signal recognition particle sRNA large type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01854"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF01854"
     gene            complement(5171..5262)
                     /locus_tag="PC466_003269"
     tRNA            complement(5171..5262)
                     /locus_tag="PC466_003269"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5226..5228),aa:Ser,seq:gga)
     gene            complement(5263..5718)
                     /locus_tag="PC466_003270"
     CDS             complement(5263..5718)
                     /locus_tag="PC466_003270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HDF2770624.1"
                     /translation="MESSFYMKEALKEAYKAYNKKETPIGAIIVKDNQIIARAHNLTE
                     TLKDSTAHAEILAIKQASEKLGGWRLTDCDLYVTMEPCIMCSGAIVNSRIKKLIIGTR
                     HVKNSYIEKQHEFKLDYFNNNNVKVAFDVLQEECSIILQEFFKALRKRD"
     gene            complement(6038..7309)
                     /gene="serS"
                     /locus_tag="PC466_003271"
     CDS             complement(6038..7309)
                     /gene="serS"
                     /locus_tag="PC466_003271"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HDF2770625.1"
                     /translation="MLDIKRIRENLDDIKKAMERRGEREFDLDAVVELDNKRREILQE
                     VEVMKNELNVNSKKIPQLIKEGKDVTEEKTRLKELSDKIKGIDEKVKEVEAKMEYTLM
                     RIPNVPHPEVPQGETDEDNVQIRTWGEPTKFDFEYKAHWDIGTGLGILDFERAGKITG
                     SRFTLYRGLGARLERSLMNFFLNTHTAKHGYTEVLPPFMANRNSFIGTGQLPKFEEDM
                     FKIEGLEYFLIPTAEVPVTNIHANEILDVAELPIKYCAYTPCFRSEAGSAGRDTRGLV
                     RQHQFNKVELVKFVKPEDSYNELESLTHDAETMLQMLGLPYRVVKICTGDLGFTAAFK
                     YDLEVWMPSYNRYVEISSCSNFEDFQARRAGIRFKRDKKSKAEYVHTLNGSGLAIGRC
                     LAAILENYQQADGSVVVPEELRPYMGVDVIK"
     misc_binding    complement(7434..7640)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(7767..8648)
                     /locus_tag="PC466_003272"
     CDS             complement(7767..8648)
                     /locus_tag="PC466_003272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HDF2770626.1"
                     /translation="MNFLSLAKAASTNSNITKRTLENMLNNFSDNIPNIIYAIIVFVI
                     GIYISKIVRKMVSRFLIKYGMSKGVNNFIVYGIYISMLSIISLISLGVIGIQTTSVVA
                     VLGAAGFSIGLAFKEILSNLGSGMIILFFKPFNIGDYIQGSGVEGTVSDIQIFSTVLK
                     TPDNKTIIIPNFQLTSNNIINYTHQNKRRIDFSYNISYDSDIDVVKSILNEIFINEKR
                     ILDDPKPIIGLNSIGNNTMQIVARPWVKTDDYWDVYFDVMEKVKNKFDENNIKVPFVP
                     SSLLFNNMSNSNTMDKR"
     gene            complement(8660..9169)
                     /locus_tag="PC466_003273"
     CDS             complement(8660..9169)
                     /locus_tag="PC466_003273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HDF2770627.1"
                     /translation="MNSDERRSKLIDILKESKCPVKGGMLAEILNVSRQVIVQDIALI
                     RARGFEIIATPQGYIIYNQPYFTKQIKCKNHRNSKEIYDELKIIVDLGGIVKDVIVNH
                     PTYGQITAELNIHSKMDIDNFMKKVETNEFKQLSVLTECSHIHTIETLKEETIEVITK
                     ELEDRGILS"
     gene            complement(9296..9412)
                     /gene="rrf"
                     /locus_tag="PC466_003274"
     rRNA            complement(9296..9412)
                     /gene="rrf"
                     /locus_tag="PC466_003274"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         3036 a         1667 c         1026 g         3796 t
ORIGIN      
        1 ctcagatact attgttatca aaatatctgg ctttatggtt tgtttcttaa tataaattaa
       61 cctactgttt aattttcaat gttcgtgttt atttcttttt ccttttttca aggacaagta
      121 atactatatc atctttatct attctagtca atataatttt ttactttttt taaatttttt
      181 atttatcatg tattctttat atttaatttt taaaacttaa tgctaagtaa acctatttat
      241 ttcataaaac taatatatat tctatgctct attttccttt ttattctata tttaaatttt
      301 ttatttacaa gaatattttt aatataacat atttgataaa attaatttac atttctttca
      361 cttgtaattt ttgcaatctt gtattagatt aatattaaaa ataatttatc aataacctta
      421 ttcacaaaga cagtttttat atatcaaaat ataatacaat ataaatacta tgctacattt
      481 taggaggatt ttattatgag caaaaaagta ttaataatgt ctgcttccac tggtggtggg
      541 cataataggg ctgctctagc tattaaagaa gaacttactt ccaaaacact tgatggagag
      601 ccaattgaat gtgaaataat agatagtttg aaattagtta ataatacaat ggataaaata
      661 atttcaagag gatacgaaaa atctgctata tatactccca aagcctatgg aagtgtatat
      721 agattatctg aaacaaatct tttgtcaaaa aatgaattta aagataatct actaataaca
      781 ttcatggcta aaaaatttaa aaagcttatt agaagcgaaa aaccagactt gattatagga
      841 acacatcctt ttccaatgat tgctctaagc acattgaaaa aaaactttaa tttacataat
      901 aatgaatcaa atgcttacac agagcatttt tataaacatt atacaaatac cattaatgtt
      961 cctccgctta tttctgtatt aaccgattat actactcatt ctacatggat acaaaatgaa
     1021 attgattact atattgttgg tcatgaatat gtaaaagaat tattggtgtt tgatggagtt
     1081 ggaccgagta aaattagaac atttggaatc cctgttgaaa aatcttttct ctctcacaga
     1141 gataaagata ttgttctttc tgagttgaat ttatctcctg ataaattaac tgttttactt
     1201 atggggggta gctttggggc tggaaatata aaagagacac ttgatgaatt actggatact
     1261 gatagagatt ttcaaatact tgtaattact ggtaagaatg aaagcctaaa agaaaaaatc
     1321 gaaaaaaaac ttatgtctcg ttatcatgat aaaaatgtat gtgttcttgg atacactgat
     1381 aagatgaatg atattttagc ttctatagat gtattagtaa gcaaacctgg tggacttact
     1441 acaactgagg ctcttttaaa agatgtacct atgatagttc cttattatat accaggtcag
     1501 gaagaagaga atcttgattt cttatctaat tgtggtgcag cacttagaac tacaaaaaaa
     1561 tataacttgt caatattact aaaagttcta atagatgacc ctagcagatt agaaatgcta
     1621 aaaagaaatg ttaaatcaat aagaaagtca aattcagccc aaaatatagc taatttaatt
     1681 ttaaatataa tttctggttg ataaaataaa taaaatccct atagtatata tattatctat
     1741 tagggatttt ttattttcta attatttaat attaaattgg ttcataaaag tcttcttcat
     1801 aatcatactg ataattttta taattatttc taaattcagc atttttattt cgtacatttt
     1861 ttttagtttt tttcttatta gaaaaactta tatcctcaaa atcatcatat ttaggtttat
     1921 cttttgattt cattttttta actctttttt ctttcattgc attatgttct tctaagttca
     1981 taattggttt catgttgcac ccctatcaaa atttttaaat gatttataca acaaattata
     2041 caatacagaa gaaatttatt caataaatct aaatcaaaat taatttgaat ttaactcaaa
     2101 aaactacaaa aatcgaggta ttaacctcga tttttatatt tctcttctgc cttctagtgc
     2161 ttttgatatt gtgacctcat ctgcatactc taaatcgcct ccaacaggaa gaccatgagc
     2221 tatccgagtg actttgattc ccattggttt tactaaccta gcaatataca tggctgtcgc
     2281 ttcaccttca atagtaggat ttgttgccat tattatttct ttgacttcct gattgccaag
     2341 tctttggata agttccttta tttttaacat atctggtcca attccatcca ttggagaaat
     2401 tactccattt aatacatgat actgtccttt aaactctctc gttctctcca tagctgctac
     2461 atctcttgga tcttccacaa cacatataac acttgaatct ctacttttat ttgaacacat
     2521 gctacatggg tctgtatctg ttatattaca acaaattgag caatatctta tttctctttt
     2581 tgcatctata atcgctttag ataaagcttc cacatcatta gtattcatat taataatatg
     2641 aaaagccaat ctttgagcag tctttcttcc tactccagga agctttgaaa attcctctat
     2701 aagtctcgtt atgggacctg tataaacttg cataaatacc acctactaga ataacccagg
     2761 tatattcata cctccagtta ccttactcat ttgacttgct tgtatatcat caatatttct
     2821 caatgcttga tttactgcac ttaaaactaa atcttgtagc atttctatat catctggatc
     2881 aactacttct ggcttgatag ttatatctat aacttctttt ttaccattaa cttttacagt
     2941 aactgctcct ccaccaactg aagcttctac ttctttactt tctaactctt gttgagcttt
     3001 ttgcatattt tcttgcattt tttgagcctg ctttaacaag ttgttcatat ttccaccacc
     3061 aggcatcatt ccgcctccaa aacctttttt agccataaac actattcctc ctaaacttat
     3121 tttcatttta ttattatatc ataatagtat tttattattt actctcattt tcatcaatac
     3181 tatattttat ttctaatatc tcttcactca ctatgttctt taatatctcc tcaccaatgt
     3241 cctttttctc tttaacttca agatttatat ctttaacttc tgatgtcagt actattttta
     3301 cattaaaact tctatttaaa acatctctta ttgttttttc taaataattt attgtatctt
     3361 gagagctcag tctagttttt gcaaaatcaa atttatcatc aaatataaca tacaacatat
     3421 tagaatatac attaaaactt tttacttcac ttaagagtgc gtatattggc atttttttat
     3481 cttttttaat ttgtttaagt atattcttcc aagatgactc tataagtata acgtcctcat
     3541 tttttacatc ttcataaact acattttctt gttttacatc tatttctcta tcgacctcat
     3601 actctttttc tttattattc ccaatttttt cagacttaaa gttccccagt tcaatcattt
     3661 tttctaagtt ctcaactctt tttataagag cttctttact ttcatcaaac attggttgag
     3721 caattttcat tatggttatt tccactaaaa cccttggatt tgaagatgac tttatatcat
     3781 cctgagttat tgataatata tttaaaatcc ttattaaatc atttatatct atatttttag
     3841 actgaatttt aagttgttct atagtttctt ctggtaatga aattatttca tccaattctg
     3901 atgaaacctt acataccatt aaatttctaa aatgatcaat taagtcattt ataagatttc
     3961 ttatatcttt gccccataag acaaattcat ttaatatctc aagagacttt ttagtgtcct
     4021 gctctacaat acattgagac aattcaaata attgttctat atttacgctt cccattaatt
     4081 caacaacatc tttataatct atcttacttt ctccaaaaga catacattgg tctaatatac
     4141 taagtgcatc tctaagagct ccttgagaat ttctagctat taaattaaga gctttatcat
     4201 ctatatcaat tccttcatct tcacaaatct ttttcattct aagggtcata tctttaactg
     4261 taactctttt aaaatcgtat ctttggcatc ttgataaaat ggttgcaggt attttgtgag
     4321 gctctgtagt tgctaatata aaaattacat atgatggagg ttcctctaag gtctttaata
     4381 atgcattaaa agctccttga gacaacatat gaacttcatc tattatatat actttatatt
     4441 tagcattggc tggagaatat ttcacacttt ctctaagctc tcttatatca tctacactat
     4501 tatttgaagc tgcatctatt tctacaacat ccattgtatt atcttttaat acagattcac
     4561 atatctcaca ctcattacac ggttcttcat ttattttatt caaacagttt actgctcttg
     4621 aaaaaatctt tgcagtagat gttttaccag tacctcttgt tccacaaaac aaataagcat
     4681 gtcctatatt atcactatat atttgatttt ttaaagtctt aataatatga tcttgaccaa
     4741 taacatcttc aaatttttgt ggtctatatg ctctatataa tgctttatgc atctttttac
     4801 ctctctttag caaaattaat aaaaaaatcc ctcattatct aagggattag tcttttatat
     4861 attaaatgct gtacaccatc tatcgactta attccatagg cgttaccaaa acagttagct
     4921 caacttaggc acccccacgg cacacaaaag tgatcactta ccgctgcttc cttccggatc
     4981 tgacggggtt catgagcttt cattgcgcag gacctaagca tcaacaccac ttatttaggg
     5041 cggccctaca gaaaataagc ctttagatgg aattcaatcc tgctatagcg gattgcaggt
     5101 tacagggcac cgctacctcc ccatctagta cagcaaaatt acaaccatat ttaattactt
     5161 tcattgtttc tggcggagag agtgggattt gaacccacga tacagtttta cccatatact
     5221 cgctttccag gcgagcgcct tcgaccactc gaccatctct ccttaatctc tttttctcaa
     5281 tgccttaaaa aattcttgca atatgatcga gcattcttct tgcaaaacat caaaagctac
     5341 ttttacatta ttattattaa aataatctaa tttaaactca tgctgttttt ctatatatga
     5401 attttttaca tgtcttgtcc ctattataag cttttttatt ctagaattaa ctattgcgcc
     5461 actacacatt atgcaaggtt ccattgtaac atataaatca caatcagtca acctccaacc
     5521 acctaatttt tctgatgctt gttttatcgc taaaatttct gcatgtgccg tagagtcttt
     5581 taacgtttct gtaaggttat gagctctagc tattatttga ttatctttaa ctataatagc
     5641 acctattggt gtttcttttt tattatatgc tttatatgct tcttttaatg cttctttcat
     5701 ataaaatgaa ctttccataa ttcctcccaa aacttataac aaacttatct tatcataatt
     5761 cattttataa ttcaacttaa ttttattttg tttatttaat tattactata tatagcgata
     5821 ttttttttaa ttagttctaa aataattttt agatattcat acaagagtgt tttataaaaa
     5881 tatttagtgt tttatgatga aaattctgct gtgtaaatta acataaaaaa actatgaaat
     5941 taatatttat aataatttca tagttttttt atttattgtt tactcataat atattctctt
     6001 catcaaagca tactctacat atacaattaa tataaattta ttttataaca tcaacaccca
     6061 tataaggtct taattcttct ggaactacta cagaaccatc tgcctgctga taattttcta
     6121 atatagcagc caaacatctt cctatcgcta atccagaacc atttaatgta tgaacatatt
     6181 ctgcttttga ttttttatct cttttaaatc ttattcctgc tcttcttgct tggaaatctt
     6241 caaaatttga acaagaagat atttctacat atctattgta acttggcatc caaacttcta
     6301 aatcatattt aaatgcagct gtaaatccca aatctcctgt acatattttt acaactctat
     6361 atggaagacc taacatttgt aacatagttt cagcatcatg agttaatgat tctaattcat
     6421 tataagaatc ttctggttta acaaatttaa ctaattcaac tttattaaat tgatgttgtc
     6481 taactaaacc tcttgtatct cttcctgctg aacctgcttc agatctaaaa caaggagtat
     6541 atgcacagta tttaattgga agctctgcaa catctaatat ttcattagca tgtatattag
     6601 taacaggaac ttcagctgtt ggtattaaga aatactctaa tccttctatt ttaaacatat
     6661 cttcttcaaa tttaggaagt tgaccagtcc ctataaaact atttctattg gccataaatg
     6721 gaggtaagac ttctgtatag ccatgcttag ctgtatgagt atttaaaaag aaattcatta
     6781 aagatctttc taatctagct cctaatcccc tatataaagt aaaccttgac ccagttattt
     6841 tccctgctct ttcaaaatct aaaataccta gacctgtccc tatatcccaa tgcgctttat
     6901 actcaaaatc aaatttagta ggttctcccc aagttcttat ttgaacattg tcttcatctg
     6961 tttcaccttg tggtacctct ggatgaggaa catttggtat tctcattaat gtatattcca
     7021 tttttgcttc tacttctttt actttctcat caataccttt tatcttatct gataactctt
     7081 tcaatcttgt cttttcttct gttacatctt ttccttcttt tattaattga ggtatttttt
     7141 tagaatttac atttaactca tttttcataa cttcaacttc ttgaagtatt tctcttcttt
     7201 tattatctag ttccactaca gcatcaaggt caaattctct ttcacctctt ctttccatag
     7261 cttttttgat atcatctaga ttttctctta ttcttttaat atctaacata ttaattcctc
     7321 ctaataattt tgataatata aattataatt ccaattaatt tacaagtatt ctagctgtaa
     7381 acttttaatt taaacaaatt tgaaaaataa aaaaagacct ccgtttaccc tataaaaggg
     7441 acgaaaatct tttatccgcg ttgccaccct aattgattat actaaaacgt ataatcctct
     7501 cagacctata acgtaggtaa accgtctagc tttaactaga agctctagag tagattcaaa
     7561 aaccattgta atgagttctc accatccact cattctctga atacaatctg ttttttacta
     7621 ttttccttca ccgcttttta actaattgtt ttatttgata atcattatat tatatatatt
     7681 aacatctttc aatactatta ttcaaatttt tttagaattt tctttaattt tttatattaa
     7741 attcactttt ttacttaatt gaaattctat cttttatcca ttgtatttga attgctcata
     7801 ttattaaata ataacgagga aggaacaaat ggaactttta tattattttc gtcaaattta
     7861 tttttgactt tttccattac atcaaagtaa acatcccagt aatcatcagt tttaacccat
     7921 ggtctagcaa ctatttgcat agtgttgttt cctatagagt ttaaacctat aattggtttt
     7981 gggtcatcca atatcctttt ttcatttata aaaatttcat tcaatatgga cttaactaca
     8041 tcaatatcac tatcatatga aatattatat gaaaaatcta tccttctttt attttgatgt
     8101 gtgtaattaa ttatattgtt acttgtcaat tgaaagtttg gtataattat ggttttatta
     8161 tctggggttt taagaacagt actaaatatt tgtatatcag aaactgtgcc ttctacacct
     8221 gagccttgaa tataatcacc tatattaaat ggcttaaaaa ataaaataat catacctgaa
     8281 cctaaatttg ataatatttc tttaaatgct aaacctatac taaatccagc agctcctaat
     8341 acagctacaa ctgatgtagt ttgtatccct ataacaccca agcttatcaa tgatataata
     8401 gataacatag atatgtatat tccatataca atgaaattat ttacaccttt actcattcca
     8461 tatttgatta aaaaccttga aaccatcttt cttactatct tagatatata gatacctatt
     8521 acaaatacga ttattgcata tataatattt ggtatattat cactaaagtt attaagcata
     8581 ttttctaaag ttcttttagt tatattacta tttgttgaag cagccttagc taatgataaa
     8641 aaattcattt aactcctcct tatgataata ttcctctgtc ctctaattct tttgttataa
     8701 cttctatagt ctcttctttt aatgtctcaa ttgtatgaat atgactacat tcagttagaa
     8761 ctgataactg tttaaattca tttgtctcaa ccttcttcat aaaattatct atatccattt
     8821 tagagtgaat attaagctct gcagttatct gaccatatgt tggatgattt acgatgacat
     8881 ccttaacaat tccacctaaa tctacaataa tctttaattc atcataaatt tctttagaat
     8941 tcctgtgatt cttacatttt atttgctttg taaaatatgg ttgattatat attatatatc
     9001 cttgaggtgt agctattatt tcaaatcctc tagctcttat aagggctata tcttgtacta
     9061 ttacttgcct acttacattt aatatctcag ctagcattcc accttttaca gggcacttag
     9121 attcttttaa aatatctatt aatttgcttc ttctttcatc agaattcata ttacaccttc
     9181 tttctaaatc aaaaacttta cctatactat ataattctat attttatctt attataaatc
     9241 aatattgatt ttatattcta tttaatatta aactttattg caaataaaaa agattacgtg
     9301 gctacgtcct actctcccag gcagtttccc accaagtacc atcagcgcta gagagcttaa
     9361 cttctgtgtt cggaatggga acaggtgtat cctctctgct attgtaacca cataatcttt
     9421 atgcttaata tttctattaa gtttttagaa tctagtaata ctagtttctt tagagttaac
     9481 actctaaaaa ctacatatat attttattga atggacatca aataa
//
LOCUS       DAMJYN010000115         9448 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.120, whole genome shotgun sequence.
ACCESSION   DAMJYN010000115 DAMJYN010000000
VERSION     DAMJYN010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9448)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9448)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9448
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.120"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(384..1787)
                     /locus_tag="PC466_003275"
     CDS             complement(384..1787)
                     /locus_tag="PC466_003275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF2770628.1"
                     /translation="MKMLNNFFKKINNPAPVFAQTKMERDNQTDDSLSTKPKTTFRDV
                     AGLDEVKEELFEIVDFMKSPQKYQKMGAKIPKGVLFYGPPGTGKTLLASAVAGETNSS
                     FFNVTGSEFVEKYVGVGAKRVRTLFEKARKEAPSIIFIDEIDAVGAKRHLESNNEKDQ
                     TLNQLLVEMDGFNKDSNVLIIGATNRLDLLDEALLRPGRFDRHIHIGAPNYHTRFEIL
                     KVHTDDKPIDKSVNLELLAKKTHGFNGAHLSNIANEAAIFAVRDDSECITSEHFDKAL
                     ERVIAGLESKNSALVEKEKKIVAYHEAGHALVSDIVGICPIQKISIVPRGQALGYVLQ
                     LPDEDRYIYTKDELIGKIKILLAGKASEELIFNHKSTGAKDDLKKVTEIANQMVCEYG
                     MSNLGFMTIDGNDKTFLCDKVQKEANRIVEICYKETLEMLKDNLEDLHSVSKFLFEKE
                     TMTHEELKDLIGKEAVN"
     gene            2664..3173
                     /locus_tag="PC466_003276"
     CDS             2664..3173
                     /locus_tag="PC466_003276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009528606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HDF2770629.1"
                     /translation="MSKELAINEQIKDKEIRVLSPTGEQLGVMPTKEAQAMANSKNLD
                     LVQISPNANPPVCKIMDYGKFRYEQARKEKEAKKKQKTIVVKEVRLRPGIEQNDLNTK
                     ANNAIKFLKKGDKVKVELRFRGRELGHKDIGKEVMLKFLDIIKEFGEPTKAPAFEGNN
                     MVVIIDPKK"
     gene            3201..3395
                     /gene="rpmI"
                     /locus_tag="PC466_003277"
     CDS             3201..3395
                     /gene="rpmI"
                     /locus_tag="PC466_003277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011721840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HDF2770630.1"
                     /translation="MPKMKTHRGAAKRLKKTGTGKLKRAKAFKKHILTKKSAKTKMNL
                     RKSTLVSDGDAKRIAQLLPY"
     gene            3451..3807
                     /gene="rplT"
                     /locus_tag="PC466_003278"
     CDS             3451..3807
                     /gene="rplT"
                     /locus_tag="PC466_003278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HDF2770631.1"
                     /translation="MARVKKAMNARKKHKKILKLAKGFRGSRSKLYRPANTFVMKALK
                     NAYIGRKLKKRDFRKLWIQRINAAARMNGISYSRLMNGLKLSGIEVNRKMLSEMAIQD
                     PEGFAKLAEVAKAKLA"
     gene            4117..4662
                     /locus_tag="PC466_003279"
     CDS             4117..4662
                     /locus_tag="PC466_003279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770632.1"
                     /translation="MNEKLMDCFVNPIKCKLLLEVFSNNRTTAKQLGEKFQDISKATL
                     YRYLNKMLKDDIIKVVEENKIRGTVEKVYAMKLDIADDVNKIIDENSGEEYAQLFTQY
                     MMGFLREFYEYAERKEKDILKEGSGFSVCPVYASIDEIVEVSKKIASILEPLRNNSHE
                     EGRRMHSIGVIITPPKEDEGK"
     gene            4649..4822
                     /locus_tag="PC466_003280"
     CDS             4649..4822
                     /locus_tag="PC466_003280"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770633.1"
                     /translation="MKGNKSDLHEVEPIYTENRFMIYICIQSKVSLHGLYFIVPFHPM
                     TWSGTMKFFNFSY"
     gene            5098..7023
                     /locus_tag="PC466_003281"
     CDS             5098..7023
                     /locus_tag="PC466_003281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HDF2770634.1"
                     /translation="MKIKFVIMPLVIFLIVLFVGCQSTKDTEVKAKDTEIKILGTGDL
                     HSILTDSMVSYVNEEREKNKNLLMVDAGDFYGTQSREMWEWSSGKKLINIKRNGRAEY
                     DDIIKSSKDEVPIVKDMAKLKYDAVVLGDNEFISNDKQSLDKLVSDFKNNNMPLVSAN
                     IYEQSGENYVQPYVMKNIKTDEGNVKVGILGLTIKEVGETLGLEDFEKDKKARELGEQ
                     ADYKGKLYANDLVEDAKKWIKVMEKESPDIIVAVVHSGEEPKTDRNPGNRIKELATTV
                     DGIDAIVAGHTHEKIDEHKYKNKSGDEVIVTQPGWHGDRVSEINFKLNKENGKWDIKE
                     KSSKLKIIDKEVSIVATADLHSHFSDKLTVDLVNERSNPIEPVVVDAGDFLDPQTDEM
                     TQWYKEWKSIRDNNSDKTISRCPMVMDMNQGMYDAVVLGNHEFVSEKDEFWSDERLLD
                     AVIEDFEQVAISVLSANIYRQSGKNYVKPYIIKDVETSEGNVKVGILGLTIKEVGKGL
                     KNVNLQEQFQYKDKLYANDLVEDAKKWVKVMKKKKPDIIVAVVHSGEEPKNPKHPGNR
                     IKELATTVDGIDAIVASHTHEKIDEHEYKNKSGEKVIVTQPGEHGKYYSKITFKVNKE
                     KGSWIINDKFSKTIEVE"
     gene            7424..9328
                     /locus_tag="PC466_003282"
     CDS             7424..9328
                     /locus_tag="PC466_003282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HDF2770635.1"
                     /translation="MKIKFIIVASIIFLIVLLVGCQSTKDTEINVLATSDLHSIIPDN
                     LISYVEEERKYDENLLMVDAGDFFDMQSGEMNKWFTGQKLVRFKDGIPEYKKIAEPRE
                     GEVPLAKKMAKLKYDAVTFGNHEFVSNDKQSLDKLVSDFKNNNIPLVSANVYEQSGEN
                     YVKPYVMKNINTDKGTVKVGILGLTIKEVGERSRFKSFKQDKKARELGEQPQYKGKLY
                     ANDLVEDANKWVKVMEKKEKPDIIVAIVHSGEEPKNPKNPGNRIKELATTVEGIDAIV
                     AGHTHEKIEQHTYKNNSGEEVIVTQPGAHGNSISKINFKLDKKNDKWFIKDKYSELKV
                     FGKEVNIITTSGLNPKFSDEMAVNLFNERDRDVQPIFIDTGDFLNTNTKEMTKWAKEW
                     QYNENKGIYKKINEWPIVYLGYDAVVLGSHEFTEDKETFEGKKSTLDYIIENFEEMKI
                     PVLSANIYDESGENYVKPYIIHNVETREGNIKVGVLGLTTTDKDEEDLSSSSLSKDSK
                     TSKIPEETGKLYTNNLVKDASEWVKVMQKESPDVIVAVVHSDNNSTLKNPSSEVKKLA
                     MSVDGIDAIVVGHTKNKVEEHIYKNKSGDEVIVTQSGEDCYSKISLELRKENGKWNII
                     NKYSKAIKMK"
BASE COUNT         3779 a         1049 c         1642 g         2978 t
ORIGIN      
        1 aagtgataga tacctaatta agttgtagat atctgataag aaatttttaa gttttcaatc
       61 gttctaaatt gtgagtataa aaatctacta aatttagtta tgtaaaatat aaattataag
      121 tgtagaaact aggctactag cttttatacc acttcaaaca ttactggaag tagttaagtt
      181 tacagcagtt tagttttatg tagatataat attctgtaaa tagacaaaat taaaatatgt
      241 aattaaaata tgtaagtgtc tcaaaatgaa atttttaatt tatgaggcac ttttttgtat
      301 aaaatcaaat atatttttat aactttaaca ataaaaagag gcttatctct attttgagac
      361 agcctcaaat ttttaaaact atattagttt acagcttctt ttcctatcaa atcttttaac
      421 tcttcatgag tcatagtttc tttttcaaat aagaatttag aaacagaatg taaatcttca
      481 agattatcct ttaacatctc taaagtctct ttataacaaa tttcaactat acgatttgct
      541 tccttttgaa ccttatcaca taagaaagtc ttatcatttc catcaatagt cataaatcct
      601 aagttactca taccatattc acaaaccatt tggttagcta tttcagtgac tttctttaag
      661 tcgtcctttg caccagtaga tttatgatta aatattaatt cttctgaagc ctttccagca
      721 agtaatattt ttatttttcc aatcaactca tccttagtat aaatatatct atcttcatca
      781 ggtaattgaa gaacataacc taatgcttgt cctctaggaa ctatagatat tttttgtata
      841 ggacaaattc ctactatatc acttacaaga gcatgtccag cttcatgata tgctactatt
      901 tttttctctt tttcaaccaa tgcagagttt ttagattcta gccctgcaat aactctttca
      961 agtgccttgt caaaatgttc tgatgtaata cactcactgt catctctaac tgcaaatata
     1021 gctgcttcat ttgctatatt tgaaagatga gccccattga aaccatgagt ttttttagct
     1081 aaaagttcta gatttacaga tttgtctata ggtttgtcat ctgtatgtac ctttagaatt
     1141 tcaaatctag tgtgatagtt tggtgcacct atatgaatgt gtctgtcaaa tcttcctggt
     1201 ctaagtaaag cttcatctaa taagtcaagt ctattggtag cacctattat taatacattg
     1261 gaatctttat taaatccatc catttcaact aaaagttggt ttagtgtttg gtctttttcg
     1321 ttgttacttt caagatgtct ctttgctcct acagcatcta tttcgtctat aaatattata
     1381 cttggagctt cttttctagc tttttcaaat agagttctaa ctctttttgc tcccacacct
     1441 acatattttt caacgaactc tgaaccagta acattgaaaa atgatgagtt tgtttcacca
     1501 gctacagcag atgcaagtag ggttttacct gttcctggag gaccataaaa taatactcct
     1561 ttaggtattt ttgcacccat tttttgatat ttttgtggtg acttcataaa atcgactatt
     1621 tcaaatagtt cttcttttac ttcgtctaat ccagcaacgt ctctaaatgt agtctttggt
     1681 tttgtagaaa gtgaatcatc tgtttgatta tctctttcca tttttgtctg tgcaaagaca
     1741 ggagctggat tgttgatttt cttaaaaaag ttgtttagca ttttcatatt cacacctcag
     1801 gtaattaatt attgttaatc aattttatat tttccatatt tactattttt tattatttat
     1861 ttttcatgga aaaaatatac atgttatcta aataaaaata aatttgtaag atgtatgaaa
     1921 aaatgaattt atgtatatag agatttctac ttatgtattg aataaagtat tacaaattat
     1981 aaattatgta ttgattatat attgagtaaa gtattataaa gcatgtattg attaagtatt
     2041 tattaagtat tgaataaaat attacaaatt tagttgaaat gaaaatgata aaaaatgttg
     2101 tgctatattt tacaaatcat ataaatagag aaattgttgt agcacaaagt aataggtagt
     2161 atattagaat ataatatagg atttgttgtg tagtatagta gcatattaga atataatata
     2221 ggatttgtta tgtagtatag tagcatatta gaatataata taggatttgt tatgtatata
     2281 gtagcatatt agaatataat gtaggatttg ttatgtagaa tatatagagt catgtagaat
     2341 ataaatatat aaaaggattt tgggtataaa tttaaaaatt aatagcaaaa tgagtagtat
     2401 agacatataa ttagtagtag gaagtaatta aatttttcct aaacaaaaaa aatagttgca
     2461 aataatttga ttaagtgata tagtaaataa ggtaagaata aaacaaagaa gaagtccgct
     2521 tctcacctta cgccggaggt tagtaaggta aatataagtt aaagcttaat tttaatttaa
     2581 gtttgtttaa atttggtaac ttatattgcg gatgattacg tcatccgctt tttattttat
     2641 aaaaattttg gaggtgtcct acaattagca aagaattagc aatcaatgaa caaataaaag
     2701 ataaggaaat aagagtcctt tcaccaacag gtgaacaact tggagtaatg cctactaaag
     2761 aagctcaagc aatggctaat agcaaaaact tagatttggt tcaaatctcg ccgaatgcga
     2821 atccaccagt atgtaagata atggattatg gaaagtttag atatgagcaa gcgagaaaag
     2881 agaaagaagc taagaaaaaa caaaaaacta tagttgtaaa agaagtaaga cttagaccag
     2941 gtattgaaca aaatgattta aatacgaaag ctaataatgc tataaagttc cttaaaaaag
     3001 gggataaagt caaagttgaa cttagattta gaggaagaga attaggacat aaagacatag
     3061 gtaaagaagt tatgcttaag tttttagata taataaaaga gtttggagaa ccaacaaaag
     3121 cccctgcatt tgagggtaat aatatggttg taattataga tccaaaaaaa tagatgatta
     3181 actgagagga ggaatttgtc atgcctaaaa tgaaaactca tagaggtgca gcaaagagat
     3241 taaagaaaac aggaactgga aagttaaaga gagctaaagc ttttaaaaaa catatattaa
     3301 ctaaaaaatc tgcaaaaact aaaatgaact taagaaaatc aactttagta agtgatggag
     3361 atgccaagag aatagcacaa ttattaccat actaagatac agattgtaaa taataactat
     3421 agaagaggga tataaaagga ggtcataacg atggcaagag ttaaaaaagc tatgaacgct
     3481 cgtaaaaagc ataagaaaat attaaaactt gcaaaaggat tcagaggatc tagaagcaaa
     3541 ttatatagac cagcaaatac attcgtaatg aaagcattaa aaaatgctta tataggaaga
     3601 aagttaaaga agagagactt cagaaaactt tggatacaaa gaataaatgc agctgctaga
     3661 atgaatggaa tatcttattc aagattaatg aatggattaa aattatctgg tattgaagtt
     3721 aacagaaaaa tgttatctga aatggctata caagacccag aaggatttgc aaaattagca
     3781 gaagttgcta aagcaaaatt agcttagtat tgaatcatga gatgtaaagt ctttgagtta
     3841 tataaataat tcaaggactt ttttattttt tgaaaaatac ttattagtgt catgtacaac
     3901 caattttata atgataaata aaataagcaa tacaatagaa ttttatgaga tttattataa
     3961 gaattgttac aattatttat catagctata aaaagtcata gtaaaaatga tattgatgta
     4021 tgtttatata tgtataaagc tttcaatcaa tcttgaatta atattatcaa catgataata
     4081 ttatcttatt aataatataa ataaggggga gataatatga atgagaaact aatggattgt
     4141 tttgtaaacc caattaaatg caagttattg cttgaagttt tttcaaataa tcgaactaca
     4201 gctaaacaat taggagaaaa atttcaagat atatcaaagg caacacttta tcgttacctt
     4261 aataaaatgt tgaaagatga tattataaaa gtggttgaag aaaataaaat aaggggaact
     4321 gttgaaaaag tatatgctat gaagttagat atagctgatg atgtgaacaa aattatagat
     4381 gagaactctg gagaagaata tgctcaactg tttactcaat atatgatggg atttttaaga
     4441 gaattttatg aatacgctga aagaaaggaa aaggatatcc taaaagaggg ttcaggattt
     4501 tctgtctgtc cagtatatgc tagtattgat gaaatagttg aagtgagtaa aaaaattgct
     4561 agtatactag aacctctaag aaataactcg cacgaagaag gcagaagaat gcattctata
     4621 ggagtgataa tcactccacc taaagaggat gaagggaaat aaatctgatt tacatgaggt
     4681 agagccaatt tacacggaaa atcgttttat gatttacata tgtatccaga gcaaagtatc
     4741 tctgcatgga ttgtacttca ttgtaccatt tcatccaatg acttggagtg gaacaatgaa
     4801 gttttttaat ttttcatatt aatgcctaaa gaaatgaact ttagaccaca tatgcaatta
     4861 ggctacatta tacaattaga ccagatatac agaataaaaa ttagtatttt tatagcagat
     4921 aaattgactg ttattcttct taaaaatcat ctattagtta ttgttagcat attgaaagaa
     4981 attatagtaa tccattgaat aaatgaatat tgcccataat catataaact gctatagttt
     5041 aaaataaagc aggacgttaa attttatagt aatcttaaaa tttaagaggg ggattttatg
     5101 aaaataaaat ttgttattat gccattggtg atatttttaa tagtattatt tgtggggtgt
     5161 caaagtacaa aagatacaga agttaaagca aaagatacag aaattaaaat attaggtaca
     5221 ggtgatttgc attcaatttt gacagactct atggtttcat atgtaaatga ggaaagggaa
     5281 aagaataaaa atctgcttat ggtagatgcg ggagatttct atggtacaca aagtagagaa
     5341 atgtgggaat ggtcttctgg aaaaaagtta attaatatta aaagaaatgg tagagcagag
     5401 tatgatgaca taattaaaag tagtaaagat gaagtaccta tagttaaaga tatggcaaag
     5461 ttgaaatatg atgctgtagt tttgggagat aatgaattta tttcaaatga taagcaaagt
     5521 cttgataaac tagtttctga ttttaaaaat aataatatgc cattggtatc agcaaatata
     5581 tatgaacaat ctggagaaaa ttatgtacaa ccatatgtaa tgaaaaatat taagacagat
     5641 gagggcaatg taaaagttgg aatactaggt cttactataa aagaagtagg ggaaaccctt
     5701 ggtcttgagg attttgaaaa ggataaaaaa gctagagagc ttggagaaca agctgattac
     5761 aaaggaaaat tatatgcaaa tgatttagta gaagatgcaa agaaatggat aaaagttatg
     5821 gaaaaagaaa gtccagacat aatagttgca gttgtacact caggggaaga acctaaaaca
     5881 gatagaaatc caggaaatag aataaaagag ttagcaacta cagtggatgg aatagatgca
     5941 attgtagctg gtcatactca tgaaaaaata gatgaacaca aatataaaaa taaatctgga
     6001 gatgaagtaa ttgttacaca accaggttgg catggagata gagtatcaga gattaatttc
     6061 aaattaaata aagagaatgg aaagtgggac ataaaggaaa agtctagtaa attaaaaata
     6121 attgataaag aagtaagtat agttgctact gcagatttac attcacattt ctctgataaa
     6181 ttaacagttg accttgttaa tgaacgtagt aacccaattg aacctgttgt agtagatgca
     6241 ggcgacttct tagaccctca aacagatgaa atgactcaat ggtataaaga gtggaaaagt
     6301 ataagagata ataatagtga taaaacgatt agtagatgcc caatggtcat ggatatgaat
     6361 cagggaatgt atgatgcagt agtacttgga aatcatgaat ttgtatctga aaaagatgaa
     6421 ttttggtcag atgaacgcct tttagatgct gttatagagg attttgaaca ggtggcaatt
     6481 tctgtgttat cagcaaatat atataggcaa tctggtaaaa attatgttaa accatatatt
     6541 ataaaagatg tggagacgag tgaaggtaat gtaaaagtag gaatattggg acttactata
     6601 aaagaagtag gtaaaggtct taaaaatgta aacttacaag agcaatttca atataaggat
     6661 aaattgtatg caaatgattt agtggaagat gcaaagaaat gggtaaaagt tatgaaaaag
     6721 aaaaaaccag atataatagt tgcagttgta cattcaggag aagaaccaaa aaatccaaaa
     6781 cacccaggaa atagaataaa agagctagca actacagtag atggtattga tgcaattgtt
     6841 gctagtcata ctcatgaaaa aatagatgag catgaatata aaaataagtc tggagaaaaa
     6901 gttatagtga cacaaccagg tgagcatggt aaatattatt ctaaaattac ctttaaagta
     6961 aataaagaaa agggttcgtg gattattaat gataaattca gtaaaacaat tgaggttgaa
     7021 taactttata aaatttatag ataaagtaaa ttatctgata ttgacatgat atataagata
     7081 aagtttctaa tattagtata atgcataatg tgaaatattt taataataag agaataaaca
     7141 agacaaataa aaatatttta acatgtaaga tatagtatga actattatac taatgcttac
     7201 tttataattt gaacatgtta gaataagtct tatttgaaaa ttttagtgta ttagagtaag
     7261 tattatttta ccagtaaaaa atattgagaa ctatatgtag atttgcttaa aaaggaattt
     7321 acatatagtt cttttcgtat aataaatagt acaatcttat atggtaaaga taaagtgtga
     7381 tattaaattt tattatcatc caaaatctaa ggaggagtct cttatgaaaa taaaatttat
     7441 tatagtagca tcaataatat ttttaatagt attacttgtg gggtgtcaaa gtactaaaga
     7501 cacagaaatc aatgtactcg ccacaagtga tttacattca attattccag ataatttaat
     7561 ttcctatgta gaagaggaga gaaaatatga tgagaatcta cttatggtag atgcaggaga
     7621 tttttttgac atgcaaagtg gtgagatgaa taagtggttt actggtcaaa aattagtaag
     7681 atttaaagat gggataccag agtacaaaaa aatagctgaa ccacgtgaag gagaagttcc
     7741 attggctaaa aaaatggcaa agctgaagta tgatgcagtt acatttggga atcatgaatt
     7801 tgtatctaat gacaagcaga gccttgataa attggtttct gattttaaaa ataacaatat
     7861 accattagta tcagcaaacg tatatgaaca atctggagaa aactacgtaa agccatatgt
     7921 aatgaaaaat ataaatactg acaagggaac tgtaaaggtt ggtatacttg gtctgactat
     7981 aaaagaagta ggggaacgtt caaggtttaa aagttttaaa caagataaaa aggctagaga
     8041 acttggggaa caacctcaat acaaagggaa attatatgca aatgatttag tagaagatgc
     8101 aaataagtgg gtaaaggtta tggaaaaaaa agaaaagcca gatataatag ttgccattgt
     8161 acattcaggt gaagagccaa aaaatcctaa aaatccagga aatagaataa aagaactagc
     8221 aacaactgta gagggaatag atgctattgt agcaggtcat acacatgaaa aaatagaaca
     8281 gcatacatat aaaaataatt ctggtgaaga agtaatagta acacagcctg gagctcatgg
     8341 taatagtata tcaaagatta attttaagtt ggataagaag aatgataagt ggtttataaa
     8401 agacaaatat agtgaattaa aggtttttgg aaaggaagta aatataatta caacttctgg
     8461 tctgaatcca aaattttcag atgaaatggc agttaatttg tttaatgaaa gagatagaga
     8521 tgttcaacct atctttatag atactggaga ttttttaaat actaatacaa aagaaatgac
     8581 taagtgggct aaagagtggc aatacaatga aaataaaggc atctataaaa aaataaatga
     8641 atggccaatt gtatatcttg gttatgatgc tgtagtactt ggtagccatg aatttacaga
     8701 ggataaagag acttttgagg gaaaaaaatc tacattggat tatattatag aaaactttga
     8761 agaaatgaag ataccagtat tatcagctaa tatatatgat gaatctggag aaaattatgt
     8821 aaaaccttat ataattcata atgtagaaac tagggaagga aatataaagg ttggagtatt
     8881 aggtcttact actactgata aggatgaaga agacttaagt agctcaagct taagcaaaga
     8941 ctcaaagact tcgaaaattc ctgaagaaac aggaaagtta tatactaata atctagtaaa
     9001 agatgcaagc gaatgggtaa aagttatgca aaaggaaagt cctgatgtga ttgttgcagt
     9061 tgtacattca gataataata gtactctaaa aaatccaagt agtgaagtca aaaaacttgc
     9121 aatgtcagta gatggaatag atgctattgt tgtaggtcat acgaaaaata aggtagaaga
     9181 acatatttac aaaaataagt ctggagatga ggttatagta acacaatctg gagaagattg
     9241 ttattcaaaa ataagtcttg aactaagaaa agaaaatggc aagtggaata tcataaacaa
     9301 atatagtaaa gcaataaaaa tgaagtgaat ttattgatat ataaaccatt attaacactg
     9361 atttttataa tataataaat actgattcta caatataatt aacactactt ttttaaatat
     9421 aataaatact gattctacaa tattatta
//
LOCUS       DAMJYN010000116         9129 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.121, whole genome shotgun sequence.
ACCESSION   DAMJYN010000116 DAMJYN010000000
VERSION     DAMJYN010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9129)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9129)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9129
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.121"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            314..970
                     /locus_tag="PC466_003283"
     CDS             314..970
                     /locus_tag="PC466_003283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770636.1"
                     /translation="MKKGDFIWSGVLICIIAVLAIPSSREVFMEATGAHPYIGGFLKF
                     AVLATMGDLLGARILYKDWKIPVGVFYRAIVWGIIGVVTTYGMSIYSSGVGQAQVDGM
                     LPFEGIAFANALFKSATMNILMSPTVFLFHKVMDCFIDKKYEVGKGIKVKLKDVVNIV
                     DWNAYLGFSVLKTIPFFWIPCHTIVFLFPAEYRVIASAFASIALGLILALANKSKVAV
                     "
     gene            complement(1440..2711)
                     /gene="sleC"
                     /locus_tag="PC466_003284"
     CDS             complement(1440..2711)
                     /gene="sleC"
                     /locus_tag="PC466_003284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore cortex-lytic protein SleC"
                     /protein_id="HDF2770637.1"
                     /translation="MQDGFLTVSIIDATNNRPIQNAVVNIYSMSNGSQSSSTLYQNLR
                     SNESGQVTGLVLPAPDVDYSLQPSDVRPYSQYIVEAIADGYETVVIEGTQLLATIVAR
                     QGVPMSPRTRSKRSFSRQSELIFDIGEHTLYGTYPPKIPESNLKPLPPPTGFVVLDNP
                     VVPEFIVVHDGLPEDSSAPNYWIPFKEYIKNIASSEIYSTWPEQTIYANVIAIISFTL
                     NRVFTEWYRNKGYNFTITSTTAYDHKFINNRNLFEPINVVVDAIFNTFIKRPPTSRQP
                     LLAQYCDGQKSQCPDQMTQWGSKDLGDQGYDYESILRYFYGDEIVFERAPIVSGVPVS
                     FPGTTLQVGSSGQYVRTIQNQLNAISNSYPAVPKVIEDGIYGADTENAVKIFQGIFGL
                     PQSGVVDFKTWYEISRVYVATTRIASLNPLI"
     gene            2956..3672
                     /locus_tag="PC466_003285"
     CDS             2956..3672
                     /locus_tag="PC466_003285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HDF2770638.1"
                     /translation="MKLDLFLLAIVPILIGMFWIRSKDRYCREPLIHLIKFFLIGAFL
                     SVIIILLENLLMKFNVFEGYSELIYVSFVVAGLVEEGVKALILIPALIKEKHFTEKLD
                     GIIYSVFLALGFATIENMVYIFSESRNLALQVGINRAVISIPAHVMFAITMGYYISKY
                     KFEGNKNKRREYLFMAVLIPILLHGVFDFILMIEYRWAIILLIVYVIILWKINLDKLE
                     KYMNHSKKVFFGNLRKKKKK"
     gene            3751..5061
                     /locus_tag="PC466_003286"
     CDS             3751..5061
                     /locus_tag="PC466_003286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmB/NOP family class I SAM-dependent RNA
                     methyltransferase"
                     /protein_id="HDF2770639.1"
                     /translation="MTELPKEFLEDIEEILKDEYDDFIKSYEESKTTGLRINTLKIDK
                     KKLFDLELFDLNQIPWAEEGFYYDDKIDRPGRNPLHEAGAYYLQEPSAMSVIPKADIK
                     EGEKVLDMCAAPGGKSTYILSKLNDTGLLVSNEINASRIKALGENLERFGARNCIITN
                     TDSNSLRKTFNGYFDKVIIDAPCSGQGMFRKDEVAISDWSYAKVVECQSIQKEIIRDG
                     YKMLKKDGILIYSTCTFSREENEHVINEFISEYPHAELIEMERLWPHKIKGEGHFVAK
                     IKKLEEEECNVKELKIKNLDKEIKDYREFEKKFLKVDFYSNKKNKFYLRGENLYLLPE
                     IYPDTKKLKVLRYGLHLGVLKKNRFEPSHALSHYLKVEDVKNVENFSVQSESILKYLK
                     GDVVNSNDSRGWVLVSVEGIPLGWGKESSGVIKNHYPKGLRKVF"
     gene            5161..5697
                     /gene="lepB"
                     /locus_tag="PC466_003287"
     CDS             5161..5697
                     /gene="lepB"
                     /locus_tag="PC466_003287"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HDF2770640.1"
                     /translation="MGEAVKKEVVEWIKVIVIALVLAFAITRFIVPTIVKGESMYPTL
                     VERDYLIVNRIAYKVGEPKYKDIIVFKTDLTEENGKKKDLVKRVIGVPGDHVKIQDSK
                     VYVNDKLLDETSYIHNNRTDGDIDIVVPEGKLFAMGDNREKSLDSRYDEVGLVDEHTI
                     LGKVLVRLYPFSKIGTID"
     gene            5863..6399
                     /gene="lepB"
                     /locus_tag="PC466_003288"
     CDS             5863..6399
                     /gene="lepB"
                     /locus_tag="PC466_003288"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HDF2770641.1"
                     /translation="MNETIKEEIVEWIKIIITALFFAFIITRFIKPTLVNGESMYPTL
                     KSHDYLVANRMTYKLSEPKCGDIMIFKTDLLQENGRKKELVKRVIGVPGDHLKIKDSK
                     VYINGKLLNEVSYIHDNYTEGDIDMVIPKGKVFAMGDNREVSLDSRYKEVGLVDEENI
                     KGKVILRVFPFTDIGIFE"
     gene            6409..7164
                     /locus_tag="PC466_003289"
     CDS             6409..7164
                     /locus_tag="PC466_003289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM barrel protein"
                     /protein_id="HDF2770642.1"
                     /translation="MAVGIASLLFNIEEALNICESIKQITHLEIGIDNISECSELCKY
                     KERISKLGLSIGIHLPMELNTCENIEYIRNSWINFIEKIEFELKGFDIRYFNLHLGYV
                     MTNRVRKNRDKYLGNSVDFLDKLNTNSYVCIENTYSKGGDFSNIGNISYDFEYIFKRI
                     KNSKICFCYDTGHCLIDEDAYVKNLKDKIRLIHLSDNDGINDTHVGIGRGILSEEGIK
                     EVLTLDAEYLVLEINYEDIEDTISKLNNIVREG"
     gene            7238..8905
                     /locus_tag="PC466_003290"
     CDS             7238..8905
                     /locus_tag="PC466_003290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside kinase"
                     /protein_id="HDF2770643.1"
                     /translation="MKKINLKIEGKDKEYSLEENSPGIRLGDIAKEFCDEHKGYITLA
                     VVDNKLKELNCRVKKDCEINFLDTTNEDGERVYFRVMSFIFVMACREIFWDSRVTIEH
                     SLSDGLYCEVHIDRKLKEADVENIKNKMKEIVNNDYVIEKIEVTRNEAISIFENNEMY
                     EKAELLKYKEYDSAKVYKCRNYIDHFYGYMLPSTGYIKSFDIKLYNGGVIILGPSEED
                     KTLPMKFVPQPKLSSVYYEAEEWSRLMGIDKVVSLNKIIENNEYGDIIRTFEALHEKK
                     LSQIADMIKDGNKRVILIAAPSSSGKTSFAHRLSIHLRVNNLNPISISLDDYFIDRKH
                     TPLDEYGNYDFESIYAIDLEKFNLDLKKLLAGEEIDDIRFNFKEGKREYTGKKIKIDS
                     NQPIILEGIHGLNPILTSSIPDEDKFKIYISALTQINLDDHNRIPTADLRMIRRIVRD
                     YNFRGYSADNTILQWASVRRGEKKNIFPYQEEADAIFNSACVYELAVLKRFAKPLLEE
                     IKEDNPAHIEATRLLKFLQYFVELDDTSDIPGISILREFIGGSKIVD"
BASE COUNT         3423 a          944 c         1706 g         3056 t
ORIGIN      
        1 aaaaaataga taattaaagg gttagggtga aagagtaatc gtaaaataaa tatatggatg
       61 atggtagata agaatatcag aaaaaaatag ataattaaag ggttagggtg aaagagtaat
      121 cgtaaaataa atatatagat aatggtggat agagtagtaa gaaaataaat agataaaggg
      181 atagaataaa tttaaatatg gaaaatgaat atctaataat aagtgattaa taaataattg
      241 tagatagatt gtaaattaaa taaatcttta atagaaagga gaactattta tatattaaat
      301 agtatttata aatatgaaaa aaggcgattt tatatggagt ggagttctta tttgtattat
      361 tgctgtctta gcaataccaa gtagtagaga agtatttatg gaagcaacag gtgcacatcc
      421 atatattggg ggttttttaa agtttgctgt attagctaca atgggagatt tacttggtgc
      481 tagaattttg tataaggatt ggaaaatacc agtaggagta ttttatagag caatagtttg
      541 gggaataata ggtgtagtta ccacatatgg aatgtcaatc tactcatcag gtgtaggtca
      601 agcacaagtg gatggtatgc ttccatttga gggaatagct tttgcaaatg ctctatttaa
      661 gagtgcaact atgaatatac taatgtcacc aactgtattt ttattccata aggttatgga
      721 ctgttttata gataaaaaat atgaggttgg aaaggggatt aaggtaaaac ttaaagatgt
      781 ggtaaatatt gtggactgga atgcttacct tggttttagt gttttaaaaa ctataccatt
      841 tttctggata ccatgtcata caattgtatt cttattccct gctgagtata gagtaattgc
      901 ttctgcattt gcatctatag ctttaggtct aatattggct ttagctaata agtctaaagt
      961 tgcagtttag gttcactgat gaagataata gtattattta aattatgaat aactttttaa
     1021 attaatatta tttatattta taataaataa taatttagat aagaaggaat attctaagtg
     1081 atagatagtg ttttaaataa taaggagtaa tattctaagt gagaagtagc attttaaata
     1141 ataagtgaga ttttaaataa aaagtaagct tttcgttaga atagcatttt attaaactta
     1201 aaaataaata taatatttta aagaaatcta agttgctaag cactgttttt aagaagctta
     1261 aaatccccca tttaaagttt taagattcta aaaaaacaag ttataactaa aaaatggctg
     1321 ttaagactac aatacttata agtaaaaata cttatggtat atattagttc ataacagcca
     1381 tttttatttt aaattaataa ttttattcaa taatttgagt ttatgttcta aatcaagctt
     1441 taaattaaag gatttaaaga agctattcta gttgtagcta cataaactct ggatatttca
     1501 taccatgttt taaaatctac tactccgctt tgaggtaaac caaagattcc ttggaatatc
     1561 ttaacagcgt tttctgtatc tgctccatag ataccatctt ctataacttt tggtacagct
     1621 ggataagaat tagatatagc atttaactga ttttgtatgg ttctaacata ctgcccagaa
     1681 gaaccaactt gtagtgtagt accagggaat gacactggta caccacttac tataggtgct
     1741 ctttcaaata ctatctcatc tccatagaaa tatcttagga tactctcata gtcatatcct
     1801 tggtcaccta agtctttact gccccattga gtcatttggt caggacattg agatttttgt
     1861 ccatcacaat attgtgctaa tagtggctgt cttgatgtag gaggtctttt tataaaagta
     1921 ttaaaaatag catctacaac tacgttaatt ggttcaaata agtttctatt atttataaac
     1981 ttatggtcgt atgctgttgt tgaagttatt gtaaagttat atcctttatt tctataccat
     2041 tcagtaaaga ctctatttaa agtaaatgat attatagcta ttacatttgc atagattgtc
     2101 tgttcaggcc aagttgaata tatttcagat gacgctatgt ttttaatgta ctctttaaat
     2161 ggaatccaat agtttggagc tgatgaatct tctggcaaac catcatgaac tactataaat
     2221 tcaggcacta cagggttatc taatacaacg aaaccagtag gaggtggtaa tggttttaag
     2281 ttactttctg gaatcttagg aggataagta ccatatagag tatgttctcc tatgtcaaaa
     2341 atcaactcac tttgtcttga gaaagaacgc ttacttcttg ttctaggaga catgggaact
     2401 ccttgtcttg ctacaattgt agctaacaac tgcgttcctt ctatgacaac tgtctcatat
     2461 ccatctgcta tggcttccac tatatactgg ctataaggtc taacatcaga tggctgtaga
     2521 gagtaatcta catctggtgc tggtaatact aaaccagtca cttgaccaga ttcattactt
     2581 cttaggtttt ggtataaagt tgatgagctt tggctaccat tagacattga atatatgttt
     2641 actactgcat tttgaatagg tctattgtta gtagcatcaa ttatgcttac tgttaagaaa
     2701 ccatcttgca tcaaatcacc ctttctttaa atgaatttag ttcccttata tttcaagata
     2761 tgaatatagc ttgaaatttg ttaaataata tagatataaa tttaaatttt tttgagtatt
     2821 tgagtatatt tgtatttaaa taatttaaaa taatttaatg tatattttag tatgtattta
     2881 aaacacaaat aagctaaaaa taagtagatg atataaatca taaataaatc aaaaattttg
     2941 aaaggaaaat aatctatgaa gctagattta tttttattag caatagttcc tatattgata
     3001 gggatgtttt ggataaggtc taaagataga tattgtagag aacccctaat ccatctaatt
     3061 aaattttttt taataggtgc ttttctaagt gttataatta tacttttaga aaatttactg
     3121 atgaagttta atgtatttga agggtattca gaactaatat atgtatcatt tgtagttgca
     3181 ggacttgtgg aagaaggtgt aaaagctctg atactgattc ctgccctaat taaagaaaaa
     3241 cactttactg aaaagttaga tggtattatt tactctgtat ttttagcttt aggatttgca
     3301 acaattgaaa atatggttta tattttttct gaaagtagaa atctagcact gcaagttggt
     3361 attaataggg cagttatctc tataccagct catgtaatgt ttgcaattac tatgggctac
     3421 tatatttcta agtataaatt tgagggaaat aaaaataaaa gacgtgagta tttgtttatg
     3481 gcagtgttaa ttccaatttt attacatgga gtttttgatt tcatattgat gatagaatat
     3541 agatgggcta ttatattact tatagtttat gtaataattt tgtggaagat aaatcttgat
     3601 aaacttgaga aatatatgaa tcactctaaa aaagtgtttt tcggtaatct taggaaaaag
     3661 aagaagaaat aaaatttaaa ggaaagacat aaataattaa agtataataa atgacacaca
     3721 agtaaagcag attgaagggg gattatagat ttgacagaat taccaaagga atttttagaa
     3781 gatattgaag aaatactaaa agatgaatat gatgatttta taaaaagtta tgaggaaagt
     3841 aagactactg ggcttagaat aaatacttta aaaattgaca agaaaaaatt atttgatttg
     3901 gagttgtttg atttgaatca aataccatgg gcagaagaag gtttttatta tgatgataaa
     3961 attgacagac ctggtagaaa tccactgcat gaggctggag catactattt gcaagagcct
     4021 tctgcaatga gtgtaatacc aaaggcagat attaaagagg gtgaaaaagt tctcgatatg
     4081 tgtgctgctc ctggtggaaa atctacatat atactatcta agctaaacga tacaggttta
     4141 ttggtttcta atgaaattaa tgctagtaga attaaggctc taggggaaaa tttagagcga
     4201 tttggagcga gaaattgtat tataacaaac accgattcta atagcttaag aaagacgttt
     4261 aatgggtatt ttgataaggt tattatagat gcaccttgtt ctgggcaagg tatgtttagg
     4321 aaggatgagg ttgccatatc agattggagt tatgcaaagg tagtagaatg tcaatccatc
     4381 caaaaagaga ttatcagaga tggatataaa atgttaaaga aggatggcat tttaatttac
     4441 tcaacttgta ctttttcaag ggaggaaaat gagcatgtta taaatgagtt tatcagtgaa
     4501 tatccacatg cagaacttat tgaaatggaa agattatggc ctcataagat aaagggagaa
     4561 ggtcattttg ttgccaaaat aaaaaaatta gaagaagaag aatgtaatgt caaagaatta
     4621 aaaataaaaa atttagataa agaaataaag gattataggg agtttgaaaa gaaattttta
     4681 aaggttgatt tttatagtaa taaaaaaaat aaattttatt taagaggaga aaatttgtac
     4741 ctacttcctg aaatatatcc agatacgaaa aaactaaaag tattgagata cggtttgcat
     4801 ttaggggttt taaagaagaa tagatttgag ccttctcatg cactatctca ttacttaaaa
     4861 gttgaagatg taaaaaatgt tgaaaacttc agtgtacaga gtgaatcaat tcttaaatat
     4921 ttaaaagggg atgttgtgaa ttctaatgat agtagaggat gggttttggt ttcggttgaa
     4981 ggaatacctt taggttgggg aaaagaatct tctggtgtaa ttaagaatca ttatcctaaa
     5041 ggtcttagaa aagtatttta aactattaga aaaaagaagt ataatattta tattgtaggt
     5101 ttatggtaga ttattttgct gtagattgac ttaatattta acacagagga gacgatttta
     5161 gtgggtgaag cagttaaaaa agaagttgta gaatggataa aagtgattgt catagctctt
     5221 gttttggcat ttgcaataac tcgttttata gtgccaacaa tagtcaaagg agaatcaatg
     5281 tatcctacat tagttgaacg tgattatttg atagttaaca gaattgcgta caaggtagga
     5341 gagccaaaat acaaagatat aatagtattt aaaaccgact taacagagga aaatggaaag
     5401 aaaaaagatt tagtaaaaag agttatcggg gttcctggtg accatgtaaa aatacaagac
     5461 tccaaggtat atgtaaatga taagttgtta gatgagactt cctatataca taataatcgt
     5521 actgatggag atattgatat cgtagttcca gaaggaaaat tatttgcaat gggagataat
     5581 agagaaaaaa gtttagatag tagatacgat gaggttggat tggtcgacga gcataccatt
     5641 ttaggaaagg ttctagtcag attgtatcca ttttctaaga taggaactat tgactaaaca
     5701 tataaaattt ggagcaatcg ctgattagct gaaatcacca gaccatacac aatagttgtc
     5761 tatataaaaa agacaacacc ttatttagta gacttatcta aaagatagtg tttaagagac
     5821 attatcaata aagataatat aactataaag gagaatttgt gaatgaatga aactattaaa
     5881 gaagagattg tagagtggat aaaaataatt attactgcac ttttttttgc atttattata
     5941 actcgtttta taaaaccaac actagtaaat ggagaatcaa tgtacccgac acttaaatca
     6001 catgattatt tggtagcaaa taggatgaca tataagttat cagaaccaaa atgtggagat
     6061 ataatgatat ttaagactga tttattacaa gagaatggaa ggaaaaaaga gcttgtaaaa
     6121 agggttatag gtgttcctgg tgaccatcta aaaattaagg attctaaggt ttatataaat
     6181 ggtaagttat taaatgaagt ttcatatata catgataatt atactgaagg cgatattgat
     6241 atggtgattc ctaagggaaa agtatttgcg atgggagaca atagagaagt tagtttagac
     6301 agtagatata aagaagtggg attggtagat gaagaaaata ttaaaggaaa agttatttta
     6361 agagtatttc cttttacaga tataggtatt tttgagtagg tgatttgtat ggcagttggt
     6421 atagcgtcct tattgtttaa tattgaggag gctttaaaca tttgtgagag tataaagcaa
     6481 ataactcatt tagagattgg aattgacaat atatctgaat gtagcgagtt atgtaaatat
     6541 aaagagagaa tttctaagtt aggattatct atagggatac acttgcctat ggaattaaat
     6601 acttgcgaaa acatagagta tatacgaaat tcatggataa attttattga gaagatagaa
     6661 tttgaactaa aaggatttga tataaggtat tttaaccttc atttgggata tgttatgaca
     6721 aatagagtta gaaagaatag agacaaatat ttaggaaata gtgtggattt tttagataaa
     6781 ttaaatacaa attcatatgt atgtatagag aatacttatt caaaaggtgg ggatttttca
     6841 aatattggaa atatatctta tgattttgaa tatatattta agaggattaa aaattctaag
     6901 atttgttttt gttacgatac tggacactgt ttaattgatg aggatgctta tgtaaagaac
     6961 ttaaaggata aaataagact gatacactta agtgataatg atggtatcaa tgatacacat
     7021 gttggtatag gaagaggaat tttatctgaa gaggggatta aagaggtctt aacattagat
     7081 gcagaatatt tagtattaga aataaattac gaagacattg aagatactat aagtaaattg
     7141 aataatattg taagagaggg ttaaatacct ctctttatct tgttgatatg cctcattaac
     7201 taaaatttat attcatcaaa aggaaggaga tgttgaagtg aaaaaaataa acttaaaaat
     7261 agaaggaaaa gataaggaat attcattaga agaaaattcc cctggaatca gattgggaga
     7321 tatagcgaaa gaattttgtg atgagcataa gggttatata acacttgcag ttgtagacaa
     7381 taaactaaaa gagctaaatt gtagagttaa gaaggattgt gagataaatt ttttagacac
     7441 tactaatgaa gatggagaga gagtttactt tagagtcatg tcatttatat ttgtaatggc
     7501 ttgtagagaa atcttttggg atagcagagt tacaatagaa cattcactat cagatgggct
     7561 atattgtgaa gttcatatag atagaaagct taaagaagca gatgttgaaa atataaaaaa
     7621 caagatgaaa gagatagtaa acaacgatta tgttatagaa aaaattgaag ttacaagaaa
     7681 tgaagctatt tctatatttg aaaataatga aatgtatgaa aaggcagagc ttttgaaata
     7741 caaagagtat gatagtgcta aagtatataa gtgtagaaac tatatagacc atttttatgg
     7801 ttatatgttg ccatcaactg gttatataaa atcatttgat attaagcttt ataatggagg
     7861 cgttataatt ttagggccta gtgaagaaga taagactctt cctatgaagt ttgtacctca
     7921 acctaagcta tcaagtgtat attatgaagc agaagaatgg tcaagactta tgggaattga
     7981 caaggtagta tctcttaaca aaataataga aaacaatgaa tatggagata taataaggac
     8041 attcgaagca ttgcatgaaa agaagttatc ccaaatagcg gatatgataa aggatggcaa
     8101 taagagagta attttaatag cagctccatc ttcatctgga aaaacaagtt ttgctcacag
     8161 attatcaata catcttagag taaataattt aaatcctatt tcaatttctt tagatgatta
     8221 ttttatagat agaaaacata ctcctttaga tgaatatgga aattatgatt ttgaatcaat
     8281 ttatgcaata gatttagaga agtttaactt agacttaaag aaacttttag ctggtgaaga
     8341 aattgatgat ataagattca attttaaaga aggtaagaga gaatacactg gtaaaaaaat
     8401 aaagatagat tcaaatcagc caattatatt agaaggtata catgggctaa atcctatttt
     8461 aacatcatct ataccagatg aagataaatt taagatatac ataagtgccc ttactcaaat
     8521 aaatttggat gaccataatc gaatccctac tgctgatttg agaatgataa gaagaattgt
     8581 tagagactat aattttagag gatatagtgc tgataatact attttacaat gggcatcagt
     8641 tagaagagga gaaaagaaga atatattccc gtaccaagag gaggcagatg ctatatttaa
     8701 ctctgcttgt gtatatgaat tagcagtttt aaaacgattt gcgaaacctt tgttggaaga
     8761 gataaaggaa gataatcctg cacatattga agctactaga ttactaaagt ttttgcagta
     8821 ttttgttgaa ttggacgata cttctgacat accaggtatt tcaattctta gggaatttat
     8881 tggaggaagt aaaatagttg attaatatgt gtattataga ttgttttatg aagattaaat
     8941 ggcatagcaa gtagtgtgat tggtttatgt taagtatatt aagtgtaaag tggagaatta
     9001 aattgataca gattttaaag tttgagttga tatataaaaa ggcttgtttt atacttttgt
     9061 atgaagcaag ctttttattt taaattttac ttttttgttt aatattttgt tagtttatgt
     9121 gataatttt
//
LOCUS       DAMJYN010000117         9091 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.122, whole genome shotgun sequence.
ACCESSION   DAMJYN010000117 DAMJYN010000000
VERSION     DAMJYN010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9091)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9091)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9091
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.122"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            26..286
                     /locus_tag="PC466_003291"
     CDS             26..286
                     /locus_tag="PC466_003291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770644.1"
                     /translation="MFKTVFEDKEYVLLCKNYSKSDGVKAIFIYLISMLLLFFQGYLY
                     TTNLSSTILTNSQMILSILILLIGLGFVLLSKEKLNTIGITM"
     gene            305..733
                     /locus_tag="PC466_003292"
     CDS             305..733
                     /locus_tag="PC466_003292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDF2770645.1"
                     /translation="MYGVIGATVLVIFVILTAGIMQGKKVDFQLPTVFMIVTFIVSAI
                     SEEIVFRGYIQTRLTGLIKNSVLSSCINAFLFLSTHYPVKWISSGDFSFAILSGFYVI
                     CLILLNFSCDLVYRKTNCLWGAWLLHILYNIGTGVLIFTT"
     gene            853..1461
                     /locus_tag="PC466_003293"
     CDS             853..1461
                     /locus_tag="PC466_003293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dienelactone hydrolase family protein"
                     /protein_id="HDF2770646.1"
                     /translation="MVDNLIKYIHKSNIAIVVLHEIYGVNNFIKDVCQKYYKGGYDVF
                     CPELLGEKRVFSYLKAQEAYDFFINNVKFDIYKKVEKLINGLKSEYKHVFVVGYSIGA
                     TIAWRCSENSLCDGIICCYGSRIRDYMDVIPTCPILLVFAKYDSFDVDYVSSQLSRRQ
                     NIQIEILDANHGFIDTYSKNYSNAQTEVFNIKEKNFLSKCLG"
     gene            1985..2197
                     /locus_tag="PC466_003294"
     CDS             1985..2197
                     /locus_tag="PC466_003294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HDF2770647.1"
                     /translation="MMPLILSNTGEEVVIKKISGSDKTRTFLNSIGFVVGTNVKIVSK
                     IDGNLIIDVKDTRVALDKKMASRIII"
     gene            2210..2431
                     /locus_tag="PC466_003295"
     CDS             2210..2431
                     /locus_tag="PC466_003295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HDF2770648.1"
                     /translation="MNRLKDIKCGETVKVKKLEGEGATRRRIMDMGITRGVNIFIRKV
                     APLGDPIEVTVRDYELSIRKSDAEKIIVE"
     gene            2531..4687
                     /gene="feoB"
                     /locus_tag="PC466_003296"
     CDS             2531..4687
                     /gene="feoB"
                     /locus_tag="PC466_003296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HDF2770649.1"
                     /translation="MSIKIGLIGNPNCGKTTMFNGLTGSSQYVGNWPGVTVEKKGGKL
                     KGNKDVEIVDLPGIYSLSPYTLEEVVTRNFMLDDKPDAVINIVDASNIERNLYLTTQV
                     LELGIPTIIALNMMDIVNKNGDKINIKELSEVIGCPVVEVTAVKGQGIMEAAEKAVEL
                     ASSNNKLNFKLPFVDESKDAIEKIEKIIEEKTPYIDVETRWLAIKLFERDENVIQKLD
                     ISKTILNSIEEITRNCEDELDDDSESIITANRYEFISSIISSIIKKNRKGKETVSDKI
                     DKIVTNRILALPIFALIMWGVYYIAVSSLGTIATDWTNDVLFGEIIQGNVSNFLASLN
                     VAEWLQGLVVDGLIGGVGAVLGFVPQIMLLFLLLSILEDCGYMSRVAFIMDRIFRKFG
                     LSGKSFIPMLISSGCGVPGVMSTRTIENDRDRKMTIMLTTFIPCGAKIPIIALFAGAL
                     FGGASWVAPSMYFLGIAMIIICGIILKKTSLFAGEPSPFVMELPQYHVPSAKGVLIHM
                     WDRGKAFIIKAGTIIFVACGVIWFLQSFNWSLQMVDAGDSILASLGNIVAPIFAPLGF
                     GNWQSSVATVTGLVAKENVVGTFGVLFGISDATEQDPTLLASVASMFTVASAFAFMAF
                     NMLCAPCFAAIGAIKREMGSWKWTWITLGFQTLTAYIIALLINQVGSLVLGTGGSIAG
                     AIISIFIAVAVVFVVLTYSNKNMKKEKMGKLSYMKN"
     gene            4713..4865
                     /locus_tag="PC466_003297"
     CDS             4713..4865
                     /locus_tag="PC466_003297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HDF2770650.1"
                     /translation="MATFIIAAIVVVLMALAVMYMVKNSKKNGSSCGCGCSGCSSSKS
                     CHSAKR"
     gene            5045..5755
                     /locus_tag="PC466_003298"
     CDS             5045..5755
                     /locus_tag="PC466_003298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AIM24 family protein"
                     /protein_id="HDF2770651.1"
                     /translation="MFKFDVTNELMCIARGSGKFFAKKGAMVAFKGNFNFEKLLLGPS
                     NGGGLGRALLGHVQRSLTGEQMPIMVVEGEGEIYLAQNAYHVDVISIDPGDSIYVESE
                     NLLAFSEQLNYSVKLIGSGVISQKGLFTTHLVNKTGQNQDVAIITDGNPLILEGPCCV
                     DPDALVAWTGREPYPKVSKLSWKTFIGQTSGESYHMEFVEPGQIVIIQPSERLSGLKT
                     DSTPSDRMSSGGLRLGID"
     gene            5840..6610
                     /locus_tag="PC466_003299"
     CDS             5840..6610
                     /locus_tag="PC466_003299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2770652.1"
                     /translation="MFEKIHKRFKGYYIFLIILILWKIVCVLGIWSSYILPPPEIVLD
                     TFIKMIYDGSIFLNVYASVRRILIGFLISSLMAIPLGVVFGVNKKMYEYFKPLFEFMR
                     STPPLALVPMLILWFGIGEESKIIIIILASFFPIFLNTLKGIKNCDNKLIEVGKSFNL
                     SKKRIFYKIIIPNSMLDIVVGLSLGLGYSFRAIIGAELIAASSGLGYLISDGKDMSRT
                     DVVLVGIFVIGFLGILSDYLFSKIITKFSKGKQVDLNG"
     gene            6603..7334
                     /locus_tag="PC466_003300"
     CDS             6603..7334
                     /locus_tag="PC466_003300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2770653.1"
                     /translation="MVRSGFLLENIYKKYLVDNKEHLVLDNISLNISSEEITVILGES
                     GCGKTTLLRILAGLENATSGNIYFFNNDKKCTPKVGMVFQESRLMPWLNVSENILLHT
                     EKDNRNKVDLDKYLKMMKLEKFKNSYPNELSGGMAHRVSIARALSFNPDILLMDEPFA
                     ALDYFTRRKMQKEVVNIHKNTKKGVVFVTHNIEEAMEIAKKIIVFSKNKRIKQFSVED
                     EYNRDLTKNYYINLKKEILRELGEF"
     gene            7368..8327
                     /locus_tag="PC466_003301"
     CDS             7368..8327
                     /locus_tag="PC466_003301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NrtA/SsuA/CpmA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HDF2770654.1"
                     /translation="MTSLIMVLVGTVGCSTTNDKKDEPAKKEASLPKEINLTYVKSPL
                     NVPSILEKKDDLFGKEFKKDNIKVNFHELTTGPEQTQALAAGELDFLHALGGTSAIIA
                     ASNGVGLKITNIYSRSPKGYMLITNNDNIKSIKDLKGKKIVGPKGTILHQLLIAALAK
                     EGYTIDDVEYVNMDIPSAASALESKSADVAMLAGPVALKTINSGAKMIVNGEGLVSGI
                     IVTAVSDDFAEKYPELVKRFMKVHEETLKYMNENKDEVMDVVSKEVGLSLDETKEMYS
                     WYDFSSKITDKDIKELEDTQEFLMSNGMQQKKINIKDMLYNQN"
     gene            complement(8425..9021)
                     /locus_tag="PC466_003302"
     CDS             complement(8425..9021)
                     /locus_tag="PC466_003302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3793 family protein"
                     /protein_id="HDF2770655.1"
                     /translation="MSCCNSQFCCKNKIESSYIKWLLEVLGPVFLGSKPAEIINISFT
                     DVNREEKINDIYKYLYKCKKIDFIVIDKEKKGLKILFVNKKALSEKLKCKKTVNFLKF
                     LGYKQNTNVNAYLEHLVNKLKSDVFPDEIGIFLGYPLKDVIGFMGYSNYEVSMIKYWK
                     VYGDTKQSEDTYSKFLLHRKKMRKLLDYISVDKIVSCF"
BASE COUNT         3390 a          963 c         1655 g         3083 t
ORIGIN      
        1 atttaattag aaaggagtat ttatagtgtt taaaactgta tttgaagata aagaatatgt
       61 tttattatgt aagaattatt ctaaaagtga tggagtaaaa gcaatattta tttatttgat
      121 atctatgtta ctattgtttt tccaaggtta tttgtataca acaaatttaa gttcaacaat
      181 tttaactaac tcacaaatga tattgtcaat cttgatttta cttatagggc tgggatttgt
      241 actactttcg aaggaaaaac taaatacgat tgggattaca atgtgaaatt taaataaaag
      301 tcttttgtat ggagttattg gtgctactgt actcgtaatt ttcgttattt taacagctgg
      361 aattatgcaa ggaaaaaaag ttgattttca attacctact gtttttatga ttgttacatt
      421 tattgtttct gctatttcag aagaaattgt ttttagaggg tatattcaaa caaggttaac
      481 tggattaata aaaaatagtg tactttcatc ttgtattaat gcttttcttt ttctatctac
      541 acattaccct gtaaaatgga tttcaagtgg agatttttca tttgcaattc tatctggatt
      601 ttatgtgata tgccttatat tacttaactt ttcatgtgat ttagtatatc gaaaaactaa
      661 ctgtctgtgg ggggcatggc tactgcatat cttgtataac attggcacag gagtgctgat
      721 ttttactact tagtcaattt tactttgcag aaagtttatc gtaagaaacg gattatttta
      781 taagtcaaat tttagagcta gtaaattgac atacttaaaa taatttaaac tagatgtaaa
      841 aaatatcgac aggtggtgga caatctgatt aagtatatac ataaaagtaa tatagctatt
      901 gttgtactgc atgaaattta tggagttaat aattttataa aagatgtttg tcaaaagtat
      961 tataaaggtg ggtatgatgt gttttgtcca gaactcttag gagaaaaaag agttttttca
     1021 tacttaaaag ctcaagaagc atatgatttt tttataaata atgttaagtt tgatatttat
     1081 aaaaaagtag aaaaacttat aaatggttta aaatcggagt ataaacatgt atttgtagtt
     1141 gggtatagta taggtgcaac tattgcatgg agatgtagtg aaaactcttt gtgtgatggt
     1201 ataatttgtt gttatggctc ccgaattaga gattatatgg atgtaattcc aacatgtcct
     1261 attttgctag tgtttgcaaa atacgattca ttcgatgttg attatgtttc ttctcaactt
     1321 tctagaaggc aaaatattca aattgaaatt ttagacgcaa atcatggttt tattgataca
     1381 tactcaaaaa actattctaa tgctcaaaca gaagttttta atattaaaga aaaaaacttt
     1441 ctatctaaat gtttaggcta atatgtttta ttataaaata tagaaaattt aatcaatttg
     1501 aaaaacataa tgacactact aatgttaaaa aatattagta gtgtcattat attttttgag
     1561 atagagatag tcagtagaat catagaatta attatgtttt tatgattgta ttagattaat
     1621 atttaaatta cattgaaaag aaaaaaatca ttactataga ataatatctt tatcaaaaga
     1681 acattcttat gcagaatatg gttatgagta tctaagagaa atctcaaaat atataggata
     1741 gcagtatgaa tttttataga ttttattaat acaataaatc aaatgagaaa aaaaatcaaa
     1801 agaatacaat aatcacttgc aaaaaatatg ctattgtgat agacttaaat caaaattagg
     1861 aattgtaaga ataaggaaaa agataagtaa ttattttaac gagtcaaaat ttaagaaatt
     1921 gtgatttata tataagatag aggttgtttg taaatttaaa ttggttgaag aggaggaata
     1981 ttatatgatg ccattgatat tatcaaatac aggtgaagaa gtagttataa agaaaatttc
     2041 gggaagtgat aagacgagga cttttttaaa tagtataggt tttgtagtag gtacaaatgt
     2101 taaaatagtt tctaagatag atggtaactt aataatagac gtaaaagata ctagagttgc
     2161 attagataaa aaaatggcaa gtagaataat aatataggga ggtaatgaca tgaacagact
     2221 gaaggatatt aagtgtggag agactgtaaa agtcaaaaag ttagaaggag aaggagctac
     2281 acgaagacgt ataatggata tggggattac aagaggtgtt aatatattta taagaaaagt
     2341 agctcctctt ggtgatccaa ttgaggtaac agtcagagat tatgaactat caattcgtaa
     2401 gtcagatgca gaaaaaatta ttgtggaata ataaagatta attagagtag ggttaatgta
     2461 attatataat gagaatgatt ttctgtatca caaacagtga tgtatttaaa taataatgga
     2521 gggaatggaa atgtcaataa aaataggtct cataggaaat cctaactgtg gtaagacaac
     2581 aatgttcaat gggcttacag gctcgtcgca atatgttggt aactggccag gagtaacagt
     2641 tgaaaaaaaa ggtggaaaat taaaaggaaa taaagatgtg gaaatagtag atttaccagg
     2701 tatttattct ttatctccat atacattaga agaagtagtt acacgtaatt ttatgctaga
     2761 tgataagccg gatgcagtaa taaatattgt agacgcatca aatatagaga gaaatttata
     2821 tcttacaact caagttttag agctaggtat accgaccatt atagctctta atatgatgga
     2881 tattgtaaat aagaatggtg ataagataaa tattaaagaa ctatctgaag ttataggttg
     2941 cccagtggta gaagtaacag cagttaaagg tcaaggaatt atggaggctg ctgaaaaggc
     3001 agttgaactt gcaagtagta acaataaatt aaatttcaaa ttaccttttg ttgatgaaag
     3061 taaggacgca atagaaaaaa ttgaaaaaat aatagaagaa aagactccat atatagatgt
     3121 agaaacacgc tggttagcta taaagctatt tgagagagat gaaaatgtta tacaaaaact
     3181 tgatatttct aaaacaatat tgaatagtat tgaagaaata actagaaatt gtgaagatga
     3241 attggatgat gatagtgaaa gtataataac agccaatcgt tatgaattta ttagttcaat
     3301 aatttcaagt ataataaaga agaatcgaaa aggtaaggaa actgtatcag ataagataga
     3361 taagattgta acaaatcgta tactagcatt acctattttt gcacttataa tgtggggagt
     3421 ttactatata gcagtaagtt cattgggtac tatagcaact gattggacaa atgatgtact
     3481 gtttggagaa attattcaag gcaatgtaag taattttcta gcttctttaa atgtagcaga
     3541 gtggttacaa ggacttgtag ttgatggtct aattggtgga gttggagcag tactaggatt
     3601 tgtaccacaa atcatgcttt tattcttatt attgtcaata ttagaagatt gtgggtatat
     3661 gtcacgtgta gcttttataa tggatagaat tttccgtaag tttggtcttt caggaaaatc
     3721 atttatacca atgcttataa gttcaggttg tggagttcca ggagttatgt caactcgtac
     3781 tatagagaat gatagagata gaaaaatgac tattatgtta actacattca ttccatgtgg
     3841 agctaagatt ccaataatag cattatttgc aggggcatta tttggaggtg cttcatgggt
     3901 agctccatca atgtatttct taggtattgc aatgataatc atttgtggaa ttatattaaa
     3961 gaaaactagt ttatttgcag gagaaccatc tccatttgtt atggaattac ctcaatatca
     4021 tgttccaagt gcaaaaggtg ttttaataca tatgtgggat agaggaaaag catttataat
     4081 caaagcagga acaattatat ttgttgcttg tggagtaatc tggttcttac aatcatttaa
     4141 ttggtcatta caaatggtag atgctggaga tagtatatta gctagcttag gaaatatagt
     4201 tgcaccaata tttgctcctc ttggatttgg aaattggcaa tcatcagtag caacagttac
     4261 aggtctagta gctaaggaaa atgtagttgg aacatttgga gttttatttg gtatatcaga
     4321 tgcaacagag caagacccaa cacttcttgc ttcagttgca agtatgttta cagtagctag
     4381 tgcgtttgca tttatggcat ttaatatgct ttgtgcacct tgttttgcag ctattggagc
     4441 cataaaaaga gaaatgggtt catggaaatg gacatggatt acattaggat tccaaacttt
     4501 aacagcgtat ataattgctc ttcttataaa tcaagttgga agtttagttt taggtactgg
     4561 aggaagtatt gctggggcaa taatatctat atttatagca gtagcagtag tctttgtagt
     4621 tttaacttat tcaaataaaa atatgaaaaa agaaaaaatg ggtaaattaa gttatatgaa
     4681 aaattaattc atataaataa ggagtgatga atatggctac atttattata gcagctattg
     4741 tagtagtatt aatggcacta gctgtaatgt atatggttaa aaattcaaaa aagaatggta
     4801 gcagttgtgg atgtggttgt tctggatgct caagtagtaa gagttgtcat agcgctaaga
     4861 gataaatagg ataagagcct gataaaaagt taaattgctt tattatcagg ttcttatttt
     4921 ttatataaat aacaaatttc atatttgaag taggttagac tatgctgtaa ttttactgta
     4981 taattatata taaatatatg attaggaggg attattgcta aattaagcaa tataagtgaa
     5041 tattatgttt aaatttgatg ttacaaacga gcttatgtgt atagcaaggg gaagtggtaa
     5101 attttttgca aaaaaaggtg ctatggtagc ctttaaagga aattttaatt ttgaaaaatt
     5161 gctgttaggt ccaagtaatg gcggtggatt gggaagagca ttattaggtc atgttcagag
     5221 gtcattgaca ggagaacaaa tgccaataat ggtggttgaa ggtgaaggtg aaatttacct
     5281 agctcaaaat gcttaccatg tagatgtaat atcaattgac ccaggtgatt ccatttatgt
     5341 tgagagtgaa aacttattgg cattttctga acaattaaat tacagtgtaa aattgattgg
     5401 ttcaggggta atatctcaaa aaggtctttt tactacacat ttagtaaata aaacaggtca
     5461 aaatcaagat gttgctataa taacagatgg taatcctcta attcttgaag gaccttgttg
     5521 tgttgaccca gatgcattag tagcttggac tggaagagaa ccatatccta aagtatcaaa
     5581 actatcatgg aagactttta ttggtcagac ttcaggagaa tcttatcata tggaatttgt
     5641 tgaacctgga caaatagtca ttatacaacc atctgaaaga ttgtctggct taaaaacaga
     5701 ttctacacct tctgatagaa tgagttcagg tggattaaga cttggcatag attaaatctt
     5761 atgatatagc ttaattatta tttaagatat taaaaaataa aaagggtagc agggatagat
     5821 atgttaaaag gagttttata tgtttgagaa aattcataaa aggtttaaag gatattatat
     5881 ttttttaata attttaattt tatggaagat agtatgtgtt ttgggtatat ggagtagcta
     5941 tattctgcct cctcctgaaa tagtcttaga tacttttata aaaatgatat atgacggttc
     6001 tattttctta aatgtttatg ccagtgtaag aaggatatta ataggttttt taataagttc
     6061 attgatggct ataccacttg gagttgtatt tggagtaaat aaaaaaatgt atgaatattt
     6121 caaaccacta tttgaattta tgcgaagtac acctccacta gctttggtgc caatgcttat
     6181 tttatggttt ggtataggtg aagaatctaa aattataatt attattttgg catccttttt
     6241 tccaatattt ttaaatacat tgaaaggtat aaaaaattgt gacaataaat taatagaagt
     6301 aggtaaatct tttaatttat ctaaaaagag aattttttat aaaataataa tccctaattc
     6361 tatgctggat attgttgttg gacttagttt agggcttggg tatagtttta gggctataat
     6421 tggagcagag cttattgcag cttcttcagg actaggatat ttgatttctg atggaaaaga
     6481 tatgtctaga actgatgttg tattggtagg aatttttgtt attggatttt taggtatact
     6541 ttcagattat ctattttcaa agataataac aaaatttagc aaagggaagc aggttgattt
     6601 aaatggttag aagtggattt ttgctagaga atatatataa gaaatattta gttgataata
     6661 aagagcattt agttcttgat aatatatctt taaatatatc tagtgaagag ataactgtta
     6721 tattaggtga aagtggatgt gggaaaacaa cgctacttag aattttagca gggcttgaaa
     6781 atgctactag tggaaacata tattttttta ataatgataa aaagtgtact ccaaaagtag
     6841 gaatggtatt tcaagaaagt agacttatgc catggctgaa tgtaagtgaa aatatacttt
     6901 tacatactga aaaagataat agaaataaag ttgatttaga caagtattta aaaatgatga
     6961 agcttgaaaa gtttaaaaac tcatatccaa atgaattatc aggaggaatg gctcacagag
     7021 taagtatagc aagagcactt tccttcaatc ccgatatttt gctgatggac gaaccatttg
     7081 cagcgctaga ttacttcaca agaagaaaaa tgcaaaaaga agttgtaaat atccataaaa
     7141 atactaaaaa aggtgtagta tttgtaactc acaatattga agaagctatg gaaatagcaa
     7201 agaaaataat tgtttttagt aaaaataaaa ggattaaaca atttagtgtc gaagatgaat
     7261 ataatagaga tttaactaaa aactattata taaacttgaa aaaagaaata ttaagggaat
     7321 tgggggagtt ttaattgatt aaaagaaaca aaaagatttt agcagtaatg acatctttaa
     7381 taatggtgtt ggttgggact gtaggatgtt caacaacaaa tgataagaaa gatgaacctg
     7441 caaaaaaaga ggctagttta cctaaggaaa taaatttaac ttatgtaaaa tcaccactta
     7501 atgttcctag tatattagaa aaaaaggatg atttatttgg aaaggaattt aaaaaggaca
     7561 atataaaagt caacttccat gaattgacaa caggaccaga gcaaactcaa gcattagcag
     7621 caggtgagct agacttttta catgcattag gaggaacgtc tgcaataata gctgcatcaa
     7681 atggtgttgg tcttaaaatt acgaatattt atagccgttc accaaaagga tatatgctta
     7741 taactaataa tgataatatt aaatctataa aagacttaaa aggtaaaaaa attgtaggtc
     7801 caaaagggac tatacttcat caactgttga ttgctgcact tgctaaagaa ggctatacta
     7861 tagatgatgt tgaatatgta aatatggata ttcctagtgc tgcttctgca ttagaaagta
     7921 aaagtgctga tgtagcaatg cttgcaggtc cagtggcatt gaaaacgata aattcaggtg
     7981 ccaaaatgat tgtaaatgga gaaggattag taagtggaat aatagttact gctgtaagtg
     8041 atgactttgc tgaaaaatat cctgaattag taaaaagatt tatgaaggtt catgaagaaa
     8101 ctttaaaata tatgaatgaa aacaaggatg aagtgatgga tgttgtatct aaagaagttg
     8161 gtttatcttt agatgaaaca aaagaaatgt attcttggta tgactttagt tctaaaataa
     8221 cggacaagga tataaaagaa ttagaagata cacaggaatt tttgatgtct aatggaatgc
     8281 aacaaaagaa aataaatatt aaagatatgt tgtacaatca aaattagaat actttaaaat
     8341 attaaagtgg aaaatacacc cttatttatt atggaaactg tatggtaaaa gagggtgtat
     8401 ttttattatt atacaaaaat acaattaaaa acaacttact attttatcta cacttatgta
     8461 gtctagtaat tttctcattt tcttacggtg aagtaaaaac tttgaatatg tgtcctcgga
     8521 ttgttttgtg tcaccataaa ctttccaata tttaatcata gaaacttcat aattactata
     8581 tcccataaat ccaatcacat ctttaagagg atatcctaaa aaaataccta tttcatcagg
     8641 aaaaacatca ctcttaagtt tatttactaa atgctctaaa taagcattaa cattcgtatt
     8701 ttgtttgtat cctaaaaact ttaaaaagtt tactgttttt ttacatttta atttttctga
     8761 taatgctttt ttatttacaa ataagatttt taatcccttt ttttctttat caataactat
     8821 aaaatctatt ttcttacatt tatatagata tttataaata tcattaattt tttcctctct
     8881 atttacatca gtaaacgaaa tatttattat ttcagcaggt ttagagccta aaaagactgg
     8941 acctaaaacc tctaaaagcc attttatata tgatgattca attttatttt tacaacaaaa
     9001 ttgtgaatta caacaagaca taaaagataa cctccttcaa atgaaaatta atatcaagta
     9061 attagattat actatgaatg ataatcaata t
//
LOCUS       DAMJYN010000118         9012 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.123, whole genome shotgun sequence.
ACCESSION   DAMJYN010000118 DAMJYN010000000
VERSION     DAMJYN010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9012)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9012)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9012
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.123"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(424..1320)
                     /locus_tag="PC466_003303"
     CDS             complement(424..1320)
                     /locus_tag="PC466_003303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDF2770656.1"
                     /translation="MKDKNTYFNRKGQENFIDIFLKDDIKKGANFKRHWHEHLQIYYF
                     IDGIAYLECGLDNFKVVPGNIVIANSNELHYLESLSDNLKFYSIRIEPTFLFSNQVDL
                     LQTKYLAPLALNHIVFNNLIQNDFLILKCITTILDEYHNKEVGYELSIKANIYQLIVL
                     LLRSHIDKIYSEDEFIKRKYSLEKFECIFDLIEEKYMDKITLKELASRVNLSAHHFCR
                     TFKQITGKTTIDFINGIRLDKAIYYLKETDLNMTEIAMRCGFDSINYFSRLFKRNYNI
                     SPTKYRNEHREVSNVILKEDMK"
     gene            1462..2889
                     /locus_tag="PC466_003304"
     CDS             1462..2889
                     /locus_tag="PC466_003304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2770657.1"
                     /translation="MTNSFKKDDNRKKITVLFVVIAMTFMATLDSSIINVALPVLASK
                     LNVSLASIEWVIASYSIIICSTLLFFGRLGDIIGKSRVFQVGTILFTSASLLCGLSNS
                     LTLLIVCRFIQGIGASAYMANNHGIITELFPKESRGKALGILVTAVAIGNMVGPSVGG
                     FILSIFDWNVIFFINIPIGLIVIFLNTKFLPNSKKSSENMDKTGAILQFLGTTLFFSA
                     LISAQQTGLLNPYILIALLLSIIFIILFLILEKKHPQPLLDLEIFRNFKFSLNLICAL
                     TSFICIASSSILIPFYLQSTMKLPPIQAGLFMILSPLILAIFSPIFGNISDKIKSEKI
                     ILIGLLVMSFGFFLMSRLKESSALILFVIYISIISIGQAIFQPANNALIMSSCSRSKL
                     GVVGSINSLVRNLGQVIGITISTTLLYNFMSIKAGYRVNDYVINNDKIFVFGMRNVYI
                     IVTLVCLIGAILIGFYLFKYNKNEQ"
     gene            complement(3086..5680)
                     /gene="clpB"
                     /locus_tag="PC466_003305"
     CDS             complement(3086..5680)
                     /gene="clpB"
                     /locus_tag="PC466_003305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HDF2770658.1"
                     /translation="MDVEKMTLRVQKSLNEAYNEAVKNHNQQVDVIHLFSALINQEDG
                     LIPNIIEKMNISIDSLRNTVNFEIDKLPKVYGEGADSQGVSATRKINEVLIKAESISK
                     EFKDSYISVEHVMLAMMETESKSAVGKILKQYNINKNDFLNILSQVRGSQRVETQDPE
                     GTYDALARYGTNLVDLAKKNKLDPVIGRDEEIRRIIRILSRRTKNNPVLIGEPGVGKT
                     AIVEGLAERIVRGDVPEGLKDKIVFSLDMGALIAGAKYRGEFEERLKAVLKEVQSSDG
                     KIILFIDEIHTIVGAGKTEGSMDAGNLIKPMLARGELNCIGATTFDEYRKYIEKDKAL
                     ERRFQPVIAEEPTVEDTISILRGLKERFEIHHGVRIHDNAIVAAAKLSHRYIQDRFLP
                     DKAIDLIDEAGAMIRSEIDSLPTELDVVRRKLFTLETEREALLKENDDKSKSRLDDIQ
                     KEIAELKSKNDEMTAKYEKEKSQILDIKNLKAQLDEAKGKAEKYEREYDFNKAAEVKY
                     GEIPKLEEQIKQYEENMNDGSENSLLKEEVTEEEISSIVSKWTGIPVTKLVEGEREKL
                     LKLEDELHKRVIGQDEAVTAVSNAVIRARAGLKDERKPIGSFIFLGPTGVGKTELAKT
                     LARNLFDSDDNIIRIDMSEYMEKHAVSRLVGPPPGYVGYEEGGQLTEAVRRAPYSVIL
                     FDEIEKAHEDVFNMFLQILDDGRLTDNKGKTVDFKNTLIIMTSNIGSNYLLEAGGNIT
                     ETTNNLVMNEMKHRFKPEFLNRVDDIIMFKPLDQENIKKIIDIFMKDLKNRLKEKDIT
                     IEVTNSAKDVMVREGYDPVYGARPLKRYIGNTLETIIAKKLIAGDVYNGCTIVIDGKD
                     ENIEVLVK"
     gene            complement(5717..6313)
                     /locus_tag="PC466_003306"
     CDS             complement(5717..6313)
                     /locus_tag="PC466_003306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770659.1"
                     /translation="MSLKLDRNVLQWFDYVFENEKTSLRHYNFNCTLKEISSTSLNKV
                     AFILEKNNSKYWKLYFEIPAEVTLKLKQNIHPLFREYIYEQISLYNNNQIYNFVNSNI
                     LKVFNNIAIYQYNILENLYTIDFKKSFIDKCQYLLIGEKRLIDEDLYLIAKSKEVFDF
                     FNSDGTFNLTLSFDIQKNENLLDSLLELRKSIIINERI"
     gene            complement(6330..6734)
                     /locus_tag="PC466_003307"
     CDS             complement(6330..6734)
                     /locus_tag="PC466_003307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication/maintenance protein RepL"
                     /protein_id="HDF2770660.1"
                     /translation="MDKTLKKDLNQEYTESKSLVMNKSKYMNICFKNYIKVVEGMYTK
                     RDLIPLKLINSMDKNNKIRKTLYELSCEFEYPKTSLSSLFTELKKMDFLQRVKNGEYM
                     INPHIAYKGSRADKESLLAEYNQIKRPNKVSK"
     gene            7101..7475
                     /locus_tag="PC466_003308"
     CDS             7101..7475
                     /locus_tag="PC466_003308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2770661.1"
                     /translation="MNIVISNSSGKPIYEQITTQIKSMIISGELPEGSALPSMRLLAK
                     ELRISVITTKRAYSDLERDGFIETVTGKGSFVSSKNMDFVKEEQFRLIEEYLQKAVDT
                     AKSSDITYDELKDILFLLYKGE"
     gene            7472..8335
                     /locus_tag="PC466_003309"
     CDS             7472..8335
                     /locus_tag="PC466_003309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2770662.1"
                     /translation="MISMDAITIKNLNKTYKDFSLQDISFSVPKGSVMGFVGENGAGK
                     TTTLKAILNLISYDSGNIEIFGLDSKKNEKEIKEQIGVVFEGSNFHENLNTDHVSKIM
                     SKIYKNWNDTLFKDYLKKLRVPDNKLIKEFSKGNKMKLSIAVALSHKPKLLILDEATS
                     SLDPIVREEILDIFLDFIQDEEHSIILSSHITSDLDKIADYITFIHKGKIVFSENKDE
                     LIDTMGVLKCKPSDFDNLSREDYSYYRKSQFGYEVLLKDKHRFISRNPNCIVDNTSIE
                     EIMLFYVRGDK"
     gene            8335..8973
                     /locus_tag="PC466_003310"
     CDS             8335..8973
                     /locus_tag="PC466_003310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 transporter permease"
                     /protein_id="HDF2770663.1"
                     /translation="MKGLILKDLLNLKGNVKFILLFIIMFGFMSSLGDGNVNNFIGVI
                     IVLCTTMIVSTFSYDDLNKWDSYVLTMPINRNDIVLSKYLTMLIFSFIGVLVSLIVSV
                     TIGYFKNTLILNETLLINALILSISVCFGSLILPLIYKFGTERARLLMILCFLVPTLA
                     LLVFKSILENISSPISIEIILNTLVYSLPFVAILLFVISYFISSKIYSKKEV"
BASE COUNT         3017 a         1320 c         1038 g         3637 t
ORIGIN      
        1 tatatttttc aggatgattt ttattataaa attttttata aatatataat ttttttatat
       61 ttatttgact ttcttttaat tctttaggat ggatttaaat tttctataaa aatcatacta
      121 ttttagctgt ttacttgctt atttgatagt tttatttctt tgattaaata tctttcagaa
      181 tctaagccag atgtctcaaa aaaactgatt tataatataa tcattttttc tgctattctt
      241 atttttccaa ttttagtttc atattaaaat atacttttca tagacactac attctttcat
      301 actcattttc acatttaact atacaagtag tcttactcat ttatgtacta tactttatta
      361 atatttatta agaaaaactc aaagatttaa aaatatatat tttctataaa gtatatttat
      421 gaattatttc atatcttctt ttaaaataac attactaact tctctatgtt catttctata
      481 cttagttgga gatatattat aattcctttt aaataagcga ctaaaataat ttatgctatc
      541 aaagccacat ctcatagcaa tttctgtcat atttaaatct gtttccttta aataatatat
      601 agctttatca agcctgattc catttataaa atcgattgta gtcttacctg ttatttgctt
      661 aaatgttcta caaaagtgat gtgcactcaa gttcacacga ctagcaagtt cttttaatgt
      721 aattttatcc atatattttt cttctatcaa gtcaaagata cattcaaatt tttctaaaga
      781 atactttctt tttataaatt catcttcaga atatatttta tcaatatgac ttcttaataa
      841 gagtactatt aattgataga tattagcttt tatagataac tcatatccaa cttctttatt
      901 gtgatattca tcaagtatag ttgtaataca ttttaaaatc agaaaatcat tttgaattaa
      961 attattaaat acaatatgat ttaaagccaa tggtgctaag tacttagttt gtaacaaatc
     1021 aacttgatta ctaaaaagga atgtgggctc aatacgaata ctatagaatt ttaaattatc
     1081 tgataagctt tctaaataat gtaattcatt actgtttgct attacaatat ttccaggcac
     1141 taccttaaaa ttatccaatc cacattcaag atatgctata ccatcaataa aataatatat
     1201 ttgtagatgc tcatgccaat gtcttttaaa gtttgctcct tttttaatgt catcctttaa
     1261 aaaaatatct ataaagtttt cttgaccttt cctattaaaa tatgtatttt tatccttcat
     1321 tattcccccc tcatcaaaat agtgctaatt ataagcaata tagttattgt attcattatt
     1381 tcatatcgct attatataaa atgtaactat cattgtaaac attaacataa tgccagtcat
     1441 tataataagg aggtaataaa aatgacaaac tcttttaaaa aagatgataa tagaaaaaaa
     1501 atcacagttt tatttgtagt cattgccatg acttttatgg caacattaga ttcgagtatt
     1561 ataaatgttg ctctcccagt tcttgcaagc aaactaaatg tatctctagc atctattgaa
     1621 tgggtaatag caagttactc aattattatt tgttcaacac tattattttt tggaagactt
     1681 ggagatatta ttggtaaatc aagagtattc caagtaggta ctattctctt tacatcagct
     1741 tcattactat gtggattaag taattcttta actttactta tagtttgccg ctttattcaa
     1801 ggaataggcg cttctgccta catggcaaac aatcatggaa ttatcacaga actatttcca
     1861 aaagaaagca gaggaaaagc cctagggatt ctagttactg cagttgctat tggaaatatg
     1921 gttggaccat ctgtgggagg atttattttg tcaatatttg attggaatgt tatatttttt
     1981 ataaatattc caatcggtct tattgtaatc tttttaaata caaaatttct tcctaatagt
     2041 aaaaaatctt cagaaaatat ggataaaact ggtgctatac ttcaattttt aggaacaaca
     2101 ttatttttta gtgctctaat tagtgctcaa caaacaggat tactaaatcc atatatatta
     2161 attgcactat tattatcaat tatttttatt atattatttt tgatattaga aaaaaaacat
     2221 cctcaaccgc ttcttgatct tgaaattttt agaaatttta aattttcatt gaatttaatt
     2281 tgtgctctta catcattcat ttgtattgca tcatcaagta ttttaattcc attttactta
     2341 caaagtacta tgaaacttcc ccctattcaa gcaggtttat ttatgatact atcacctttg
     2401 attttagcca ttttttcacc tatatttggg aatatatcag ataaaatcaa gtcagaaaaa
     2461 attattttaa ttggtcttct cgttatgagt tttggattct ttctaatgtc aagattgaaa
     2521 gaaagttctg cccttatttt atttgtaatt tatatatcga taatatcaat aggacaagct
     2581 atatttcaac ctgctaacaa tgctttgata atgtcaagct gttctagaag taagctagga
     2641 gttgtaggaa gcataaattc ccttgtaaga aatttaggac aagttatagg tattactatt
     2701 tctacaacac ttttatataa ttttatgagt attaaagctg gatatagggt caatgattat
     2761 gtgattaata atgataaaat atttgtattt ggaatgagaa atgtttatat tattgttaca
     2821 cttgtttgct taataggtgc aatattaatt ggcttttatt tatttaaata taataaaaat
     2881 gaacagtagt tttttataat tatattcaaa ttatgattat attataagaa acttactaaa
     2941 atacttcctt tgagttaaat ttaatttgga catattgact taaaaatgtt ttattaattt
     3001 gataaaatat ttcttttcct atagtttata aataaaaatc agctgagcaa aatatttagt
     3061 atattatgct caactgattc ttttattatt taactaaaac ttcaatattt tcatcttttc
     3121 catctataac tatagtacat ccattataca catctccagc aataagtttc tttgcaatta
     3181 tagtttctaa tgtatttcct atatatctct taagaggtct tgctccatat acagggtcat
     3241 atccttctct caccataaca tcttttgctg aatttgtaac ttcaatagta atatcttttt
     3301 cttttaatct attttttaaa tctttcataa atatatctat aattttcttg atattttctt
     3361 ggtctaaagg cttaaacatt ataatatcat ctactctgtt taaaaactca ggtttaaatc
     3421 tatgcttcat ttcattcatt actaaattgt tagtagtctc tgttatattt cctcctgctt
     3481 ctaatagata attacttcct atattagaag tcattattat aagagtattt ttaaagtcta
     3541 ctgtcttacc tttattatca gtaagtctac catcatctaa tatctgtaag aacatgttaa
     3601 atacatcctc atgtgctttt tctatctcat caaatagtat tacagaataa ggagcacgtc
     3661 taactgcttc tgtaagttga ccaccctctt catatcccac gtaccctgga ggaggtccaa
     3721 ctagtcttga tacagcatgt ttttccatgt attcagacat atctattctt attatattat
     3781 cgtcactatc gaataaattt ctagcaagag tttttgcaag ttcagtttta ccaacacctg
     3841 tagggcctaa gaaaataaat gaaccaattg gttttctttc atcttttaat cctgctcttg
     3901 cacgtattac tgcatttgaa actgctgtaa ctgcttcatc ttgtccaata actcttttat
     3961 gaagttcatc ttctagttta agtaattttt ctctttctcc ttcaactagt ttagttactg
     4021 gtatacctgt ccactttgat acaatgctag atatttcttc ttcagtaact tcttctttta
     4081 aaagagaatt ttcagaacca tcattcatat tttcttcgta ctgctttatt tgttcttcta
     4141 acttaggtat ttcaccatat ttaacctctg ctgctttgtt gaaatcatat tctctttcat
     4201 acttttcagc tttaccttta gcttcgtcta attgagcctt taagttttta atatctaata
     4261 tttgactctt ttctttttca tattttgctg tcatttcatc atttttagat tttaactctg
     4321 ctatttcttt ttgaatatca tccaatcttg atttgctttt atcatcattt tctttaagta
     4381 atgcttctct ttcagtttct aatgtaaata actttcttct aacaacatct aattctgttg
     4441 gcaatgaatc tatttcacta cgaatcatag ctccagcttc atcaattaaa tcaattgctt
     4501 tatctggtaa aaatctatct tgtatatatc tatgagaaag ttttgctgct gctacaatag
     4561 cattatcatg tattcttact ccatgatgta tctcaaatct ttcttttaaa cctctaagta
     4621 tagatattgt gtcttcaaca gtaggttctt ctgcaattac aggctgaaaa cgtctttcaa
     4681 gagccttatc tttttctata tactttctat attcatcaaa agtagttgca ccaatacagt
     4741 tcaattcacc tcttgcaagc ataggtttaa taagattacc tgcatccatt gaaccttctg
     4801 ttttaccagc tccaacgata gtatgaatct catctataaa cagtataatc tttccatcag
     4861 aactttgaac ttcttttaaa actgccttta atctttcttc aaattcacct ctatattttg
     4921 caccagcaat taaagctccc atatcaagtg agaatacaat cttatctttt aaaccttctg
     4981 ggacatctcc tcttactatt ctctctgcta acccttctac aattgcagtt ttacctacac
     5041 ctggctcacc aatcaataca ggattatttt ttgttcttct tgataaaatt cttataatcc
     5101 ttcttatttc ttcatctctc ccaattacag ggtctaattt atttttcttg gctaaatcta
     5161 ctaagtttgt tccatatcta gcaagtgcat catatgtgcc ttctgggtct tgtgtttcta
     5221 ctctttgact acctctcact tgtgataaaa tatttaaaaa gtcattctta tttatattat
     5281 attgttttaa tattttacca acagctgatt ttgattctgt ttccatcatt gcaagcataa
     5341 catgctctac acttatatat gaatctttaa attctttaga aatactctct gcctttataa
     5401 gcacctcatt tatttttcta gtagctgata ctccttgtga gtcagcacct tctccatata
     5461 cttttggaag cttatcaatt tcaaagttta cagtatttct caaagaatca attgatatat
     5521 tcattttttc gattatattt ggtatcaatc catcctcttg attaataagt gctgagaaaa
     5581 gatgaattac atctacttgt tggttatgat tttttactgc ttcgttataa gcctcattta
     5641 aacttttttg aactcttaaa gtcatttttt ctacgtccat ataaatccct ccattttaat
     5701 attatatcca aataaattaa attctctcat ttataattat tgattttcta agctctaaaa
     5761 gactatcaag taaattctcg tttttttgta tatcgaaact caatgttaaa ttaaatgttc
     5821 catctgaatt aaaaaaatcg aatacttctt ttgattttgc tattaaatac aagtcttcat
     5881 ctataagtct tttttcacct attaataaat actgacattt atctataaaa ctctttttaa
     5941 aatcaatagt gtatagattt tctaaaatat tatattgata aatagcaata ttattaaaca
     6001 cttttaatat gtttgaattt acaaaattgt aaatttgatt attgttatac agtgatattt
     6061 gttcgtatat atattcccta aataaaggat gaatgttttg cttaagtttt aaagtaactt
     6121 cagctggtat ttcaaaataa agcttccagt acttagagtt atttttttct aaaataaaag
     6181 ctactttgtt caaactggta gaactaatct cctttagtgt acaattaaaa ttatagtgtc
     6241 tcaaactagt tttttcattc tcaaatacat agtcaaacca ctgtagaaca tttctatcaa
     6301 gttttaaact catataaaaa ccttcttcct tatttactaa ccttattagg tctttttatc
     6361 tgattatatt ctgctaataa actttcttta tcagctctac tacctttata tgctatatgt
     6421 ggatttatca tatactcacc atttttcact ctttgtaaaa aatccatttt tttcaactcc
     6481 gtaaacaatg aagataaaga agtttttgga tattcaaatt cacaagataa ttcatataat
     6541 gtttttctaa tcttattatt tttatccata gagtttatta attttaatgg aattaaatcc
     6601 ctcttagtat acattccttc tactacttta atataattct taaaacaaat attcatatac
     6661 ttacttttat tcataactaa acttttgctc tctgtatatt cctgatttaa atcctttttt
     6721 aatgtcttat ccaaattaaa tatctcttct cactctcctt atctctaatt gataatataa
     6781 atatattaca aaaaaatatg tatgtcaaaa ctgaaaatgc aaaaagttta ccttataagt
     6841 aaacttttgt ttagctataa gctaaacttt attatttttt taatttagta tttccaattt
     6901 attggcagga tttttgaata atatttataa attttttaaa aaaatttaaa tctatttaat
     6961 atggcagcct ttcataaaat acattacatt tattaaatgt ataatattgg taattagttt
     7021 tttctaaaat cagttgacat attatatata tatttatata atgtgtatat actatatata
     7081 caatttaagg aggtgactta ttgaatatag ttattagtaa ttcgagtggg aagccaatat
     7141 atgaacagat tactacacaa attaaaagta tgattataag cggagagtta ccagaaggct
     7201 cagctcttcc aagtatgaga ctattggcaa aggaacttag aataagtgta attactacaa
     7261 aacgagcata tagcgattta gaacgagacg gatttattga gacagttact ggtaaaggca
     7321 gttttgtatc tagtaaaaac atggattttg tcaaagaaga acaatttcgt ttaattgaag
     7381 aatacctaca aaaagcagtt gatacagcaa aaagtagtga tattacatat gacgaattaa
     7441 aagatatttt atttttatta tataaaggag aatgataagt atggatgcaa taactataaa
     7501 aaatttaaat aaaacttata aagattttag cctacaagat atatcttttt cagtaccaaa
     7561 agggagtgta atgggatttg taggtgaaaa tggtgcagga aaaacaacta cattaaaagc
     7621 aattttaaat ttaatatctt atgatagtgg aaatatagaa atatttggtc ttgatagtaa
     7681 aaaaaatgaa aaagaaatta aagagcaaat tggggttgta tttgagggaa gcaactttca
     7741 tgaaaattta aacactgacc atgtttcaaa aatcatgagt aaaatctata aaaattggaa
     7801 tgacacatta tttaaagact acttaaaaaa attgagagta ccagacaata aattaattaa
     7861 ggagttttca aaggggaata agatgaaact tagtattgct gtagccttat ctcataaacc
     7921 aaaattatta atactagatg aggcaactag ttcacttgac cctatcgttc gtgaagaaat
     7981 actagatata tttttagatt ttatacaaga tgaagaacac tctattatct tatcttcaca
     8041 tattacaagt gatttagata agatagcaga ctatattaca tttatacata aaggaaaaat
     8101 tgtatttagt gaaaataagg atgaattaat tgatactatg ggagttttaa aatgtaaacc
     8161 tagtgatttt gataaccttt caagagagga ttattcatat tatcgtaaaa gccaatttgg
     8221 atatgaagta cttcttaaag ataaacatag atttatatca agaaatccaa attgtattgt
     8281 tgataatacg tctatagaag aaattatgtt attttatgtg agaggtgata aataatgaaa
     8341 ggtttaattt taaaagattt acttaatttg aaaggaaatg taaagtttat acttttattc
     8401 atcattatgt ttgggtttat gtcttcttta ggagatggaa atgttaataa ctttataggt
     8461 gttattatag ttttatgtac tacaatgatt gtttcaacat tttcatatga tgatttaaat
     8521 aaatgggata gttatgtact tacaatgcct attaatcgca atgatattgt attaagtaaa
     8581 tatttaacta tgttaatatt tagctttata ggtgttcttg tttcacttat tgttagtgta
     8641 actattggtt attttaaaaa tacacttata ttaaatgaaa cactacttat taatgcacta
     8701 atcttatcaa tttcagtatg ttttggtagc cttattctac cacttattta taaatttggt
     8761 acagaaagag ctcgtttatt aatgatttta tgctttttag ttccaacact agctttatta
     8821 gtttttaaaa gtattttaga aaatattagt tcacctattt ctatagaaat tatacttaat
     8881 acactagtat attctcttcc atttgttgct attttactat ttgtgatttc atattttata
     8941 tcatcaaaaa tctatagtaa aaaagaagta taaaatatac tatacatgtc tctgtattta
     9001 agtattttaa at
//
LOCUS       DAMJYN010000119         8979 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.124, whole genome shotgun sequence.
ACCESSION   DAMJYN010000119 DAMJYN010000000
VERSION     DAMJYN010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8979)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8979)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8979
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.124"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            30..1034
                     /locus_tag="PC466_003311"
     CDS             30..1034
                     /locus_tag="PC466_003311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HDF2770664.1"
                     /translation="MRFKRILILMLTVAMIAGMLVGCANNPSNNPSSSKDNKSDISDK
                     SNSKKSVSMILDIEGTNNEAMNNAALLALNNAQKKLNIDTNKVESDDSSTFSNSIDIL
                     CNDNYDLIIAVGARFAKPLEMVAKKYPKQQFAIIDYEYDKQPSNITSISYEDNKSGYL
                     AGLIAGKMTESDKVGFIGGIKSSSRDKFESGFREGVKFSNSSIKDISVEYADVFKDSK
                     SVESIAKKMMDNGVDIIFSTTEDDSKAVIDAVRAKNKKVIATNKDQHELAPENVISSI
                     VKDFENPTYNLIQSFVKGNYKGGKVIENTVKSGSTGLAQNSSQNIPPDVLEYVNKNNK
                     "
     gene            1159..2271
                     /locus_tag="PC466_003312"
     CDS             1159..2271
                     /locus_tag="PC466_003312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HDF2770665.1"
                     /translation="MKIKRILMACFVVVFTIFILAICNFDFGFDKVNKNNSNIDSAKS
                     KQSESKSVPTSAEKDKLNSKSKNEEDDTEDDSYVRKTIGVLLDTENLNNESYNNNVLS
                     ALKRADEDFDVRIKLEKPKTSKSFKESIEKLHKYEPDLIIAVGARFAEPIKEAATKYP
                     KQQFAIVDYTYKVQPANVISVSFQDNVTGYLAGLIAGKMTDTGKVGFIGGVEGSSRDK
                     YESGFRKGLKTSNKDAELLVKYSNIFENPESARTIAKEMRDSDRDVVFSATEDDSKRA
                     IQVARENGGKVIAINKDQYDMAPDNVISSIIKDVEQPVYELIKNVAKDGFKGSKVMEF
                     KIKDGELGLTSKSSRNIPPDVLEYIKKEYNKVKDTY"
     gene            2694..3455
                     /locus_tag="PC466_003313"
     CDS             2694..3455
                     /locus_tag="PC466_003313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770666.1"
                     /translation="MEFTREPFILDDDLCLALVDKRISYLMENELKLRNIEIIKTIEC
                     KELYESIKYHPDICICNLGKGDIIVAPNVYNQYKELLSRYKFNIIKGEANLLNRYPYD
                     IPYNIAIVGDYAIHNFKYTDKAILDYIENNKLKKINIEQGYSKCSICIVDRTSIITSD
                     KGIWKSMKNTEIECLLIEKGHINLFEMNYGFIGGCTGLISKDKLAFCGDVKKHPDYER
                     IKSFVESKNKEIVTLSCENLLDIGSIVPLMTRKER"
     gene            3458..4276
                     /locus_tag="PC466_003314"
     CDS             3458..4276
                     /locus_tag="PC466_003314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sporulation protein YtxC"
                     /protein_id="HDF2770667.1"
                     /translation="MVEKDNISSMKFLRNNNVNDRLIYTNDIVEVVIDSAKQEVLNKK
                     ILNGTKAEQRALNIDEISTEITSMIISIMKEKLLKEYILKCYGRTYPEDKNNIYIYSL
                     NIFAKKEIFMRETVFTRVRNYIEENDFINVEGFIRFRMREFMKYISAIGDIAVEEYLI
                     KKDQDEFIRVLKYFIDTQEEKIDLLKVHIMEDNTFVLYDKNGNKIDSIDDEEIINMVI
                     RENLNYEDFLISTLLTLCPKKIEILDLLNNNCSKEIIDTVEAIFENKVSIIMEN"
     gene            4456..5058
                     /locus_tag="PC466_003315"
     CDS             4456..5058
                     /locus_tag="PC466_003315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF445 family protein"
                     /protein_id="HDF2770668.1"
                     /translation="MDNLIRILILAVIGGFIGYVTNVVAIRLIFRPIEPIKIPILNIE
                     IVGLIPKRRAEIAANVGEIIQEEFLSMDEILANIITDEDKEEVVRYIKARVKIIIHEK
                     VSFIPSGIKNMIQDYLGEIIESEVKQSIDELSKNIINKANERIDIQKMVEDKINELDL
                     YELEEIIIRIAKKELKHIEFLGLVLGFLIGIAQGLITMFI"
     misc_binding    5568..5806
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            5870..7789
                     /gene="thrS"
                     /locus_tag="PC466_003316"
     CDS             5870..7789
                     /gene="thrS"
                     /locus_tag="PC466_003316"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HDF2770669.1"
                     /translation="MIKVALKDGSIKEFENAISVMDVAKSISEGLARNVVAASVNGEV
                     VGLDHIIDTDCDLNLFKFEDKEGKEVFRHTSAHILAQAIKRLYPEAKLAIGPSIENGF
                     YYDIDLDHRLVPEDLEKIEAEMKKIAKEDLKIERFELPRNEALELMKEQGEDYKVELI
                     SDLPESEIISFYKQGDFTDLCRGPHLPSTKKVKAVKLQSVAGAYWRGDENNKMLQRIY
                     GTSFEKNKDLEEYLHLLEEAKKRDHRKLGKELGLFMIPEEGPGFPMFLPKGMELKNEL
                     LKFWREIHRKAGYIEIESPIILNRKLWETSGHWYHYKENMYTVKIDDEDYAIKPMNCP
                     GGLIYYNSQLHSYRDFPMRVAELGRVHRHELSGALQGLMRVRAFTQDDSHIFMLPEQI
                     KDEIKGVANLIDGIYKTFGFEYNLELSTRPENSMGSDEEWEAAENGLREALEELGLPY
                     TINEGDGAFYGPKIDFHLKDCLGRTWQCGTIQLDMQLPRQFDNTYIGQDGEKHRPVMI
                     HRVAFGSIERFIGILIEHYAGKFPVWLSPTQVKILPISDKFMDYANEVKKELFDKGIR
                     VELDDRAEKIGFKIREAQLEKVPYMLIVGEKEVADNNVSVRSRDKGEIGSIKLDEFIA
                     SISKEIESRESIIQD"
     gene            8557..>8979
                     /locus_tag="PC466_003317"
     CDS             8557..>8979
                     /locus_tag="PC466_003317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770670.1"
                     /translation="MIEKVEEKSKIIKTSKEYKRTIIEEKDKEWTKKLNDILSRSSFC
                     NDELDKIKALIPKEILTNENVGEVVTEDGYAKPEYDEVFKSLFTLNNEYDLLVNFIND
                     ILKDAPYANRNIKPFTQIKRIIRVETDPTINYIGEKRPR"
BASE COUNT         3636 a          878 c         1620 g         2845 t
ORIGIN      
        1 tatcgtaaat gtatgaggag tgaaatttaa tgcgtttcaa aagaatattg atattgatgt
       61 taactgtagc aatgatagct ggaatgttgg ttgggtgtgc taataaccca agcaataatc
      121 ctagctctag caaagataat aaaagtgata taagcgataa aagtaattca aaaaaatctg
      181 tatcaatgat actagatatt gaaggaacaa ataatgaagc tatgaataat gcagctttat
      241 tagcattaaa caatgctcaa aagaaactta atatagatac aaacaaagtg gaatcagatg
      301 attcctcaac tttttctaat agtatagata ttttatgtaa tgacaattac gatttaatta
      361 tagctgtagg agctagattt gcaaaaccat tggagatggt agccaagaaa tatccaaagc
      421 aacaatttgc aattatagac tatgagtatg acaagcaacc ttctaatata acttcaattt
      481 cttatgaaga taataaatct ggatacctag ctggattaat tgctggaaaa atgactgaaa
      541 gcgataaggt tggttttata ggaggaataa agagttctag tagggataaa tttgaatcag
      601 gttttagaga gggtgttaaa ttttctaata gtagtataaa ggatatttca gttgagtatg
      661 cagatgtttt taaagatagc aaatcagtag aatctatagc taaaaaaatg atggataatg
      721 gagtggatat tattttttct actactgaag atgattcaaa agctgtaata gatgcagtaa
      781 gggcaaaaaa taaaaaagtt atagcaacga ataaagacca acatgagtta gctccagaaa
      841 atgttataag ttctattgta aaagattttg agaatcctac ttataatctg atacaaagtt
      901 ttgtaaaagg aaattataaa ggcggaaaag ttatagaaaa cacagttaag tctggaagta
      961 ctgggcttgc ccaaaatagt tctcaaaata ttcctccaga tgtgttagaa tatgttaata
     1021 agaacaataa ataatctact ataatatcca agaatactta tgactttagt tatgaggtga
     1081 attggatgtt ataatagaca tatatagaaa gacgtatgca gaggtaggca gacctatcta
     1141 aatcagggag tgaattttgt gaaaataaaa aggatattga tggcttgctt tgtagtagtt
     1201 tttacaattt ttatattagc tatatgtaac tttgattttg gatttgataa agtaaataag
     1261 aataattcta atatagatag tgctaaatcg aaacagagtg agtctaaaag tgtaccaact
     1321 tcagcagaaa aggataaatt aaatagtaaa agtaagaatg aagaagatga cacagaagat
     1381 gattcatatg taagaaaaac tattggagta ttgttagata ccgaaaactt aaataacgaa
     1441 tcatataata ataatgtact atcagcctta aaaagggctg atgaagattt tgatgttagg
     1501 ataaaacttg aaaaaccaaa gacttctaaa agttttaaag agagtataga aaaactacat
     1561 aagtatgaac cagatttgat aatagcagtt ggagctagat ttgcagagcc aattaaagaa
     1621 gctgctacta aatatcccaa acagcaattt gcaatagttg actatactta taaagttcag
     1681 ccagctaatg taatttctgt atcatttcaa gataatgtta ctggatattt agcagggctt
     1741 attgcaggta aaatgactga tactgggaaa gtcggtttta taggcggagt tgagggttct
     1801 agtagagata agtatgaatc tggatttaga aaggggctta aaacttcaaa taaagatgct
     1861 gagttactag ttaagtattc aaatatattt gaaaaccctg aatcagctag aactattgca
     1921 aaggaaatga gagattctga tagagatgtt gtattttcag ctacagaaga tgatagtaaa
     1981 agagctattc aggtagcaag agaaaatggt ggtaaagtta tagctattaa taaagaccaa
     2041 tacgatatgg ctccagataa tgtaataagt tcaattataa aagatgtaga acaacctgtc
     2101 tatgaactga taaagaacgt tgcaaaagat ggttttaagg gaagtaaagt aatggaattt
     2161 aaaataaaag atggagaact tggcttgact tcaaagagca gtagaaatat accaccagat
     2221 gttttggaat acataaaaaa agagtataac aaagtgaaag atacatatta attattgatg
     2281 tagaagatta taaaaatata ctgtttaagt ttagattagc aataaaaaga tatatttatt
     2341 aaatttgtgc taactgtaca aaatatattg attaagttta gattggtgat aaaaagatat
     2401 atttattaaa tttagtctaa ctgtacaaaa tatattgatt gagtttagat tagcaataaa
     2461 aagatatatt tattaaattt gtgctaactg tacggaatat actgcttaag tttagattag
     2521 tgataaaaag atatatttat taaatttgaa ccaactgtac aaagctatac taattaagct
     2581 tagattaact atataaaatt ataacaataa gtgtgtgggc agaaaaattc tgctacacac
     2641 tttatttata ttcatataaa aaaattatca aaaaaaagaa aaaggagtaa aaaatggaat
     2701 ttacaagaga accatttata ctagatgacg atttgtgtct agctttggtg gacaaaagaa
     2761 ttagttatct aatggaaaat gaattaaaat taagaaatat agagataata aaaacaatag
     2821 aatgtaaaga attatatgaa agcataaaat atcacccgga tatatgtatt tgtaatttag
     2881 gaaaaggaga tataattgtt gcgccgaatg tatataatca atacaaagag ttattaagta
     2941 gatataaatt taatataatt aagggagaag ctaatttatt aaatagatac ccttatgata
     3001 taccttacaa tattgcgata gttggtgact atgctataca caattttaag tatactgaca
     3061 aagcaatatt agattatatt gaaaataata aacttaaaaa gataaatata gagcagggct
     3121 attctaaatg ctcaatctgt atagtagata gaacgtctat aataacatca gataaaggta
     3181 tttggaaaag tatgaagaat acagaaatag agtgtttatt gatagaaaaa ggtcacataa
     3241 atttatttga gatgaattat ggatttatag gtggatgtac agggttgatt tctaaggata
     3301 aactagcttt ttgtggagat gttaaaaaac atcctgacta tgaacgtata aaaagttttg
     3361 tagaaagtaa aaacaaggag atagttacac ttagctgtga aaatttacta gatataggtt
     3421 ctatagttcc tctcatgaca agaaaggagc gataactttg gttgagaagg ataatatttc
     3481 ttccatgaaa tttttgagga ataataatgt aaacgataga ttaatatata cgaatgacat
     3541 tgtagaagta gtgatagatt ctgcaaagca agaagtgtta aataaaaaaa tacttaatgg
     3601 tactaaagct gaacaaagag ctttaaatat tgatgagata tcaacggaaa taactagtat
     3661 gataataagt ataatgaaag agaaactttt gaaagaatac attctaaaat gctatgggcg
     3721 tacatatcct gaagataaaa ataatatata catatattca ctgaacatat ttgctaaaaa
     3781 agagattttt atgagagaaa cagtatttac tagggtgaga aattatatag aagaaaatga
     3841 ttttataaat gtagaaggtt ttattagatt tagaatgaga gaatttatga aatatatttc
     3901 tgctataggt gatattgcag ttgaggagta tttaataaag aaagaccaag atgaatttat
     3961 aagagtttta aaatacttta tagatactca agaagaaaag attgatttgc ttaaagttca
     4021 tataatggaa gataatacat ttgttttata cgataaaaat ggaaataaga tagacagtat
     4081 agatgatgaa gaaattataa atatggtaat aagagaaaat ttaaattatg aggacttttt
     4141 aataagtacc ttattaactc tatgtcccaa aaaaatagaa atattggatt tgttaaataa
     4201 taattgctca aaggaaatta tagatactgt agaagcaatt tttgaaaata aagttagtat
     4261 aattatggaa aactagaatc taagcatata aaagctagcc atataaaatt aaaaaaattc
     4321 tttttaaatc gacacaaaag acttataatt gtatataaag ctatagtata actagagtta
     4381 ttaagtataa agaatatcta cttgattaat gcaatatagc tggcaaatat acaattgata
     4441 aggagtaatt ttataatgga taatttaatt aggatactga tattagctgt tattggtgga
     4501 tttataggtt atgttacgaa tgtagttgct ataagactga tatttagacc aatagagcct
     4561 attaaaatac ctattttaaa tatagaaata gtaggtctta taccaaagag aagagcagaa
     4621 atagcagcaa atgtaggaga aataattcaa gaagaatttc tttctatgga cgaaatactt
     4681 gcaaatatca ttactgacga agataaggaa gaagttgtaa gatacataaa agcaagggta
     4741 aaaattataa tacatgagaa agtttcattt atcccgagtg gtataaaaaa catgatacaa
     4801 gattatctag gagagataat tgagtctgaa gttaagcaaa gtatagatga attgagtaaa
     4861 aatataataa ataaagcaaa tgaacgtata gatatacaaa aaatggtcga agataagatt
     4921 aatgaactag atttatatga attggaagag ataataataa gaatagctaa gaaagaatta
     4981 aaacatatag agtttttggg gcttgtctta gggtttttaa taggtatagc tcaagggtta
     5041 attactatgt ttatttaaat atatgagaag tagcatttat ttaagtacta attatattta
     5101 cctatttgag tgaattactt attaatagta tttagatatt aattgtattt acctatttga
     5161 gtgaattact tattaatagc atttagatat taattgtatt tatttatttg attgtgttac
     5221 ttattaatag tatttaagta tttactgtac tacttattaa ctatattaag tattgattgt
     5281 atttaagtat acaaaaccta aaaagagtac aaaaattaga agttagtttt aataaaaatt
     5341 agttttagta tttatctagt catatctatc atgcatgtgg atacgtttta aaaattttaa
     5401 atttatgaaa atattataat atcactataa atcaagagat taatttaata taaaaatata
     5461 agaatattgg tttacagctg attgagatga aaaataatgg gtaattaata tattacatta
     5521 atgttgattg atgtataact atctgttata atgaaaatat attaaaaatc atagtgttga
     5581 agaggaagag tagagtagaa accattctca gagaatttgg gtctatggct gagagcccat
     5641 gtaataggtc tatttgaaaa ctaccttgga gctgagctta ttagcagtat ttgtatttgt
     5701 actatacgtg aaagtgctcg ggtgacgacc ttatagtcat caagagggtt gtatatactt
     5761 gtatacgcca acttgggtgg aaccgcgaat taatatcgtc ccaaacatat ttggggcgat
     5821 tttttattac aaaaaatcta aaaattattt caataaggag gaaaaaacaa tgattaaagt
     5881 tgctttaaaa gatggctcaa taaaagaatt tgaaaatgct atttctgtta tggatgtagc
     5941 taaatccatt agtgaaggat tagctagaaa tgtggtagca gcgtctgtga acggagaggt
     6001 tgtaggtctg gaccacatta tagatactga ttgtgacttg aatttattta agtttgaaga
     6061 taaagaaggt aaggaagttt ttagacatac atcagcacat atattagctc aagctataaa
     6121 aagactttac ccagaagcaa agcttgctat aggaccaagt atagaaaatg gattctacta
     6181 tgatatagat ttagaccata gattagttcc agaggaccta gagaaaatag aagctgaaat
     6241 gaaaaaaata gctaaagaag atttaaaaat agaaagattt gaacttccta gaaatgaagc
     6301 tttagagctt atgaaagaac aaggagaaga ctataaggta gaacttatat ctgatttacc
     6361 tgaaagtgaa ataatatctt tctacaagca aggtgatttt actgatttat gtagaggacc
     6421 acatttacca tctactaaaa aggtaaaagc tgttaaatta caaagtgtag caggtgcata
     6481 ttggcgtggt gacgaaaata ataagatgct tcaaagaata tatggaactt cttttgagaa
     6541 aaacaaagac ttagaagagt acttacattt actagaagaa gctaaaaaga gagaccacag
     6601 aaaattaggt aaagaattag gattatttat gatacctgaa gaaggtccag gattccctat
     6661 gtttttacca aaaggtatgg aacttaaaaa tgaattatta aaattctgga gagaaataca
     6721 cagaaaagct ggatatattg agatagaatc tccaatcata ttaaatagaa aattatggga
     6781 gacttcagga cactggtatc attacaaaga aaatatgtat acagttaaaa tagatgatga
     6841 ggattatgct ataaaaccta tgaactgtcc tggtggatta atttactata actctcaact
     6901 acattcatat agagatttcc caatgagagt tgcagagctt ggtagagttc atagacatga
     6961 gttatctggt gcattacaag gattaatgag agttagagca tttactcaag acgattcaca
     7021 tatattcatg ttaccagagc aaattaagga cgaaataaaa ggagtagcta acttaataga
     7081 tggtatctac aaaacttttg gatttgaata taatttagaa ttatctacaa gaccagagaa
     7141 ctctatggga agcgacgaag agtgggaagc agcagaaaat ggattaagag aagctttaga
     7201 agagttaggt ctaccatata ctattaatga gggtgatgga gcattctatg gtcctaagat
     7261 agacttccat ctaaaagatt gtttaggaag aacttggcaa tgtggtacta tccaattaga
     7321 tatgcaactt ccaagacaat ttgataatac ttatattggt caagatggtg aaaagcatag
     7381 accagttatg attcataggg ttgcttttgg tagtatagaa agatttatag gtatattaat
     7441 agagcattat gctggtaaat tcccagtttg gttatctcca actcaagtta agatacttcc
     7501 tatatctgat aaatttatgg attatgcaaa tgaagttaag aaagagttat ttgataaggg
     7561 tataagagtt gaattagatg atagagctga aaaaattgga tttaagataa gagaagctca
     7621 gcttgaaaaa gtgccataca tgttaatagt aggtgaaaaa gaagtagctg ataataatgt
     7681 ttctgttaga tcaagagata aaggtgaaat aggtagtatt aaattagatg aatttatagc
     7741 tagtatttca aaagaaattg aatcaagaga aagtattatt caagactaat atataatata
     7801 ttagtagcta agatattgtt atataagata agtttaatca atatgttgat atgttgatac
     7861 atagtgatta aatttatgaa aagatgagta taattagagg tacagttaat catattttta
     7921 tgattaatgt acctctagtt ttttgtatgg tagatttatt aataaatata tcatagaagt
     7981 gttttgaaca tggaaatatt tatgtgcatt ctttaaataa aagtttattt tttgaatgat
     8041 aattaagtgc ttgttggtaa ggttatggct gtaaaaatca taactttatt tttatatttg
     8101 ttccattttc ataaaaatta ttatcccttt aagaaaattt cttaatcctc ttgaaatatt
     8161 tcctttttag tctaaagtta aatttctttc ttcaaaatga atatttaaat gaactaaaat
     8221 ttaagtacat tttctaatct tatgagtcta tttttcatag ataattgccc tataatagaa
     8281 gaatctatgt tggggctatg tggtgacaat aacagcattg tcagtgatta attaatgctt
     8341 tataaatgat taattagtgt tttatgttat ttttggactt accctctata catagattaa
     8401 tttatttaac tttagatata gagagaatgt caagtacata cacagacatt agagtttaag
     8461 aaagtgttta tggagcaaga acttttaaaa gaagtagtga cttagtttaa tttcaagaaa
     8521 tgataaatac aaaagaggaa aaagagaggt gttgaaatga tagaaaaagt agaagaaaaa
     8581 tctaagatta ttaaaacatc aaaagaatat aagcgaacta taattgaaga aaaagataaa
     8641 gaatggacca aaaaattaaa tgatatactt agtagaagta gtttttgtaa tgatgaatta
     8701 gataaaatca aggcgttaat tccaaaagag attttgacta atgaaaatgt tggagaagtt
     8761 gtgactgaag atggatatgc taagcccgag tatgatgagg tatttaaatc attgttcact
     8821 ttaaataatg aatatgattt acttgtaaat tttataaatg atattctaaa agatgctcca
     8881 tatgctaaca ggaatatcaa accgttcact caaataaaga gaataattag agttgaaact
     8941 gatccaacaa ttaattacat tggagagaaa agacctaga
//
LOCUS       DAMJYN010000120         8919 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.125, whole genome shotgun sequence.
ACCESSION   DAMJYN010000120 DAMJYN010000000
VERSION     DAMJYN010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8919)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8919)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8919
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.125"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            77..418
                     /locus_tag="PC466_003318"
     CDS             77..418
                     /locus_tag="PC466_003318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family transcriptional regulator"
                     /protein_id="HDF2770671.1"
                     /translation="MKEENFINVEYEDKRFSINSKEVLYIEKQEYEVKIYTESGNYEV
                     GENAPCIRKLLKEENFFKCSNSYIVNLDKCEFYLSNNCIFVNNNFIRILGSERKKKLK
                     KKLEKLYDYED"
     gene            569..982
                     /locus_tag="PC466_003319"
     CDS             569..982
                     /locus_tag="PC466_003319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1653 domain-containing protein"
                     /protein_id="HDF2770672.1"
                     /translation="MIELKNNLGISERKLKYPCIYKHFKGKYYATMGLSKAIDDIENI
                     CEIYGKENLIQNRNKYKLVIRHTEREEDIYVYRDLDGNLYHKKEEDTNDLVLYKTLYD
                     DTGIFARPLDMFLEKVDTDKYVNSIQEYRFEEVYK"
     gene            1184..1825
                     /locus_tag="PC466_003320"
     CDS             1184..1825
                     /locus_tag="PC466_003320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HDF2770673.1"
                     /translation="MGNTFYIVRHGQTDWNILGKTQGHGNSDLTPQGIEQAKELSEDI
                     GKYSIDYIFSSDLGRAMQTAQILGDKLNIEVQKTEALREMGFGVWEGLLIKEIQKDYS
                     DIYATWRNEPHLVNIPEGETLKIIKERVDAFIKELNEKYDNKNIILVTHSITLRVMLL
                     SFLESGMENIYRIKQDNTALNIVEFKDYGPVIVKMNDTSHIKNHVKINNSALE"
     gene            1849..3102
                     /locus_tag="PC466_003321"
     CDS             1849..3102
                     /locus_tag="PC466_003321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDF2770674.1"
                     /translation="MSKVIVVGGGASGMMAALSASKNNNEVILVERNGELGRKLRATG
                     GGRCNFTNNREIEDFFDKVVSNKKFLYSSFYTFTNKDLISYFESRNLEYKIEKENDHK
                     VYTKNDKSIEVIEVLNKDLLNHNVKIMYNKKVIDIITEEIALKDDSNKDKSKYLIKGI
                     ILDNGDKILGDKVIISTGGVSYSKTGSDGSMYKILKKHGHTLNKLYPALVPLTIEEKW
                     IKDLQGISMKNVEISCKIKKRKISKSGDMLFAHFGITGPCVLIMSSYINKIIEKEKVE
                     LNIDFLPNLSTDEISSIIRAFPNKNVLNNLKQILPQNFLREIFSLLSLVDKKASDLSK
                     ADEIRIIEYIKNMKLTCNGTTGINTGMVTSGGISVKEINSSTMESKLVKNLFFTGEVI
                     DIDAETGGYNLQIAFSTGYLAGISV"
     gene            3148..3798
                     /locus_tag="PC466_003322"
     CDS             3148..3798
                     /locus_tag="PC466_003322"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HDF2770675.1"
                     /translation="MGNLVIAVDGPAGAGKSTIAKIVAKKLNINYIDTGAMYRAVTYK
                     CLKSGVDVNNEKEVIQIAENSDIDFKDNNIYLDKEVINEEIRTIEVSNNVSNVAKIKE
                     VRQLMVEVQRKIGMKSSVILDGRDIGSYVFPDADYKFFLVATPEERGNRRYKELCNKG
                     YNTTLEEVIEDIIRRDEIDSNREFAPLVKANDALEIDTTGKTIEEVVEEVVSKINL"
     gene            3849..4445
                     /locus_tag="PC466_003323"
     CDS             3849..4445
                     /locus_tag="PC466_003323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HDF2770676.1"
                     /translation="MNFYRFVINIFKGFSKIFFKYEVIGAENIPDRGNIVIASNHKSN
                     LDPIFLAAAIENREIAAIAKKELFKVKPLGFILKKLHVMPINREKPDVSTIKTILRSV
                     RDGYVLGIFPEGTRIKGDSFGKAKAGLSVFTIKSKSKVVPVSIISKYKLFSKVIVYIG
                     EPISFEEHFKEKLSNDDHERISQEILEVIKQNYFKYSK"
     gene            4458..5297
                     /locus_tag="PC466_003324"
     CDS             4458..5297
                     /locus_tag="PC466_003324"
                     /EC_number="1.17.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-3-methylbut-2-enyl diphosphate
                     reductase"
                     /protein_id="HDF2770677.1"
                     /translation="MNIKIAKNAGFCFGVKRAMKMAWDEVEKNDSGIYALGPLIHNKQ
                     AVAKYEEKGLKTVNEIDTIPNHENMIIRSHGVPENIYKEAKDKKLKIVDTTCPFVKKI
                     HTVVSEYHNKGYEIIVIGDMKHPEVIGINGWCENSAIIIKTLEQMENMEFNNSKKYCL
                     VAQTTINPELYISIVNKLSDKLEEIVFNDTICSATKTRQESAKELAKEVDCMIVIGGK
                     HSSNTQKLVKVCEDLVPTFAIETKDELDVNTLKKYKNLGITAGASTPNWIIEEVVTFL
                     ENL"
     gene            5542..6696
                     /locus_tag="PC466_003325"
     CDS             5542..6696
                     /locus_tag="PC466_003325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenic efflux protein"
                     /protein_id="HDF2770678.1"
                     /translation="MEMLISASEEAFLHVGSMIGFFILLFGYINYKTSGNFTNIISKN
                     RKFQPLIGALIGAIPGCGGSLAIMPLYINGKLSFGAIIASLIASMGDAAFVLISSNIK
                     MYFFVTIVSTITGIITGQLVDYFKLEEKLGLKNRRKSDKYDISKNNPKENKEQHNHDE
                     IILDTLAKSHGNTNRLAFIITHGKGYKFYIGIIVIGFIFMSLAHSGLNLPIIEKLHSL
                     EEVIAVIGILFSIIYMWCFKKVFKNSNQKEEENKKISLREMLIHSVGEISFVITWIFI
                     AYLIYDLIILILGGDEYLVKLVLSTGVISVFIGAGLGLIPGCGIQIVLMSFYLKGTIP
                     LGAVIANSISQDGDALFPLLAMDKKSSLWAMIITTIPAILVGMIVYAFLG"
     gene            7002..8699
                     /gene="ade"
                     /locus_tag="PC466_003326"
     CDS             7002..8699
                     /gene="ade"
                     /locus_tag="PC466_003326"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HDF2770679.1"
                     /translation="MGNLKRQCDVSSGREKADIVLKNGTIINVFTEELITGDVAIVGD
                     TIVGIGDYKGNVEIDCSNKYISPGFIDAHMHIESTMVMPIELSKKLLKSGTTTIIADP
                     HELVNVKGASAIDFLLESTKDIPLNVYIMVPSSVPATSFETNGVGKFSAKDMESYVNN
                     PRILGLGEVMCFNDVINSENEILDKLELFKNKVVDGHAPNINGKSLQTYVCAGIENDH
                     ECITFDEVYEKLRAGLKILIREGSAAKNLKSIVSGMLKHNLPIEEFMFCTDDKHLDDI
                     EKQGHIRWNIKCAIDLGMEPVRAIKVATYNSAKAYGLRKIGAIGAGYKADIVVLNDLD
                     KMEVDSVYKDGNLVNEEMFSNYNYEIKDKELLNTVKFKYINKEKIQLKVSEKNYVMEI
                     VPYQILTNKVYESLPCADGYFVPNKEYSKLCVVERHRMTGNVAIASLKGFGIKNGAIA
                     TTVAHDSHNIIVAGDNDDDILVAINYLKEIQGGYVIVSNGKVLAHLSLQVAGLISTFT
                     AEEVQEITDNMLEIARKMGVPEYVDPFITLSFMALPVVPQIRLTDLGLFDVEEFKFI"
BASE COUNT         3646 a          860 c         1582 g         2831 t
ORIGIN      
        1 ttacatatat ttccgataga ttatattgat aaaaaacact aaaattaaat taataaaagt
       61 acttggaggg atggaaatga aagaggaaaa ttttattaat gttgaatacg aggataaacg
      121 tttttcaatt aatagtaaag aagttttgta catagaaaag caagagtatg aagtaaagat
      181 ttatactgaa agtggtaatt atgaagttgg agaaaatgct ccttgtataa gaaaactatt
      241 gaaagaagaa aattttttca aatgcagtaa tagttatatt gtaaatctag acaagtgtga
      301 attttatctc agcaataatt gtatttttgt gaataataat tttataagaa ttttaggttc
      361 agaaagaaaa aagaaattaa aaaagaaatt agaaaaatta tatgattatg aagattaata
      421 ttgggaggct gtattttata cagcctcttt atttattgat tgtattatta ataaatttta
      481 aattatgata aaatataaaa caagtaactt atttcagaat aaaatacttt ttaaaagaaa
      541 gggacgagat atgggagatt ataataaaat gattgaatta aagaataact taggtatcag
      601 tgaaagaaag ttaaaatatc cttgtatcta taaacatttt aaagggaaat attatgctac
      661 aatgggtctt agcaaggcta ttgatgatat agaaaacata tgtgaaatat atggtaaaga
      721 aaatttaatc caaaacagaa ataaatataa attagttatt agacatactg aaagagaaga
      781 agatatctat gtttataggg atttagatgg aaacctttat cataaaaaag aagaagatac
      841 taatgattta gttttataca agaccttata tgatgataca ggaatatttg caagaccttt
      901 ggatatgttt ttagaaaaag tagatacaga taagtatgtc aattcaattc aagaatacag
      961 atttgaagaa gtatataaat aatataagag aaatatgttt ataaatttag aaaaattctt
     1021 taacagtaca ataatttgca gaaatacaaa tgagatttat tgtaaataat atgttagatt
     1081 agattataaa atagaaacaa agtaaagtat tatatgatat aattaagttt tgagaagtga
     1141 taatttatat ttaataaaaa ataggcatat attaggagga catatgggaa atacttttta
     1201 tatagtaaga catggacaaa cggattggaa tatattggga aaaacacaag gtcatggtaa
     1261 ttctgacctt acgcctcaag gtatagaaca ggcaaaagaa ctttctgaag atattggcaa
     1321 gtattcaatt gattatattt ttagtagcga ccttgggaga gcaatgcaaa cagctcaaat
     1381 tttaggagat aagctcaata ttgaagttca aaaaactgag gcacttagag aaatgggatt
     1441 cggagtttgg gaaggccttt taataaaaga aattcaaaaa gattattcag atatatatgc
     1501 aacatggaga aatgaaccac acttagtaaa tataccagaa ggcgaaactc ttaagattat
     1561 aaaggaaaga gtagatgctt ttataaagga actaaatgaa aaatatgata ataaaaatat
     1621 aattcttgtt acacattcaa ttacattgag ggttatgttg ttgtcatttt tagaatcagg
     1681 tatggaaaat atatatagaa ttaagcaaga taatactgct ttaaatatag tagaatttaa
     1741 agattatgga cctgttatag taaaaatgaa tgatacaagt catataaaaa atcatgtaaa
     1801 gataaataat tctgcactgg agtaggaatc aattataagg agaaatttat gagtaaagtt
     1861 atagtagttg gtggaggagc ttctggaatg atggcagctt tgtcagcttc aaaaaacaat
     1921 aatgaagtaa tattagttga gagaaatgga gaattaggaa gaaaacttag ggcaactggt
     1981 ggcggtagat gcaattttac caataataga gagatagaag atttttttga taaagttgtc
     2041 agtaataaaa aatttctcta tagtagtttc tatacattta caaataaaga ccttatttcg
     2101 tattttgaaa gtagaaattt ggaatataag attgaaaaag aaaatgacca caaagtatac
     2161 actaaaaatg ataaatctat agaagtaata gaagtattaa ataaagattt actcaatcac
     2221 aatgtaaaga taatgtataa taagaaagtt atagatatta taactgaaga aattgctcta
     2281 aaagatgatt ctaataagga caagtcaaag tatctaataa aagggattat tttagataat
     2341 ggagataaga tactaggaga caaggttatt atatcaactg gaggagtgag ttattcaaag
     2401 acgggttcag atggttcaat gtataagatt cttaaaaagc atggacatac attaaacaaa
     2461 ctatatcctg ctttagttcc acttacaata gaggaaaaat ggattaaaga tttacaagga
     2521 atatccatga agaatgtgga aatatcttgt aagattaaga aaaggaaaat atcaaaatct
     2581 ggagacatgc tatttgccca ttttgggata acaggacctt gtgttcttat aatgtcttct
     2641 tatattaaca agattattga aaaggaaaag gtagaattaa atatagattt cttaccaaat
     2701 ttaagtactg atgaaatctc tagtataatc agagcatttc caaataaaaa tgttctaaat
     2761 aatcttaagc aaatactacc tcaaaatttc ttaagagaga ttttttctct attatcttta
     2821 gttgataaaa aggcaagtga tttgtctaag gcagatgaaa ttagaattat tgagtatata
     2881 aaaaatatga agctaacttg taatgggact acaggtataa acactggtat ggttacttct
     2941 ggtggtattt cagttaaaga aattaattct tctactatgg aatctaaatt agttaagaac
     3001 ttatttttta caggtgaagt aattgatata gatgcagaaa ctggtggata taatttacaa
     3061 atagcatttt caactggata tcttgcgggt ataagtgtat aaatataatt ttttaataat
     3121 taaatatgaa taaatagagg tgtatatatg ggtaatttag ttatagctgt agatggtcca
     3181 gcaggagctg gaaaaagtac aatagccaag atagtagcaa aaaagctaaa tataaattat
     3241 atagatacag gtgctatgta cagagcagtt acttataagt gtttaaaaag tggtgttgat
     3301 gtcaataatg aaaaagaagt tattcaaata gctgaaaatt cggatataga ttttaaagat
     3361 aacaatatat atttggacaa agaagttata aatgaagaaa taagaacaat agaagtaagc
     3421 aataatgttt ctaatgtagc aaaaataaaa gaagtaagac agttgatggt tgaagttcaa
     3481 cgaaaaatag gaatgaaaag ttcagtaata ctagatggta gagatatagg ttcatatgtt
     3541 ttcccagatg cagattacaa attcttttta gtagctactc cagaagaaag aggaaataga
     3601 cgctataaag aactttgtaa taaaggatat aatactactt tagaagaagt aattgaggat
     3661 ataataagac gagatgaaat tgattcaaat agagaatttg caccattggt aaaagctaat
     3721 gatgcactag aaatagatac tacaggaaaa actatagaag aagttgtaga agaagttgta
     3781 tctaaaataa atctttagtt ttttatgcat cataatgaaa ataaatgtag tgttgaaggg
     3841 agataaacgt gaatttttat agatttgtaa taaatatttt taagggtttt tctaaaatat
     3901 tttttaaata tgaagttata ggtgcagaga atattccaga tagaggaaat atagtaatag
     3961 catcaaatca taaatcgaat cttgacccta tattcttggc tgctgccata gaaaataggg
     4021 aaatagctgc aattgcaaag aaagaattgt ttaaagtaaa gccattggga tttatattaa
     4081 aaaaattgca tgttatgcct ataaatagag aaaaaccaga tgtatctaca ataaaaacta
     4141 ttttaaggtc agttagagat ggttatgtat taggaatatt tccagagggt actagaataa
     4201 aaggagattc ttttggtaag gctaaggcag gtctttctgt atttacaata aaaagtaaat
     4261 ctaaagttgt tccagtatca ataatatcta aatataaact ttttagtaaa gtaattgtat
     4321 atattggaga accaatatca tttgaagaac attttaagga aaaattgagt aatgatgacc
     4381 atgaaaggat atcacaagag attttagaag tgataaaaca aaattacttt aaatattcaa
     4441 aataaggggg taaagttatg aacataaaaa tagcaaaaaa tgctggcttt tgttttggag
     4501 taaaaagagc aatgaaaatg gcatgggatg aagttgaaaa aaatgattct ggcatatatg
     4561 ctttaggtcc tcttattcat aacaagcaag cagtagcaaa atatgaagaa aaaggtctta
     4621 agactgtgaa tgaaattgat acaataccaa atcatgaaaa tatgataata aggtctcatg
     4681 gagttcctga aaatatatat aaggaagcca aagataaaaa attaaaaatt gtggatacta
     4741 catgtccatt tgtaaagaaa atacatacag tagtaagtga atatcataat aaaggctatg
     4801 aaataatagt tattggagat atgaagcatc cagaagttat aggtataaat ggatggtgtg
     4861 aaaattcagc tataataata aagaccttag aacaaatgga aaatatggaa tttaataact
     4921 ccaaaaaata ttgtcttgtt gcacagacta caataaatcc agagttgtat ataagtatag
     4981 ttaataaact atcagataaa ttagaagaaa tagtatttaa tgatacaatt tgttcagcta
     5041 caaaaacaag acaagaatca gctaaagagt tagctaaaga agttgattgt atgatagtta
     5101 taggaggtaa acacagttca aatactcaaa agttagtaaa ggtttgtgaa gacttagtac
     5161 caacttttgc aatagagact aaagatgaat tggatgtaaa tacgcttaaa aaatataaaa
     5221 atttgggtat tacagcaggg gcatctacac ctaattggat aatagaagaa gttgtaacat
     5281 tccttgaaaa tttataattt gataggtaat aaaaataggt ggacattgtt ataatttatc
     5341 ataatatcca cctttgattt catattacat gtggtaaata gataacctaa tatcaaaaag
     5401 tgtgtatctt aagatgaaaa actaagagta taagatgcgc actttttaat attaaaaatt
     5461 caaaagaaat attgatattg attatcaata gaaaatagaa tataatataa ttgttgcaaa
     5521 attagtctag gaggtaaatt aatggaaatg ttgatatccg cttctgaaga ggcgttttta
     5581 catgtaggtt ctatgattgg attttttatt ttgttatttg gatatattaa ttataaaact
     5641 agtggaaatt ttactaatat catatcaaaa aacagaaaat ttcaaccctt aataggtgct
     5701 ttaattggag ctataccagg ttgtggcgga agtctggcaa taatgccatt gtatataaat
     5761 ggaaaattaa gctttggagc aataattgca agtttaatag ctagtatggg agatgcagca
     5821 tttgtactta tttcatcaaa tattaaaatg tatttttttg tcactatagt tagtacaatt
     5881 acaggaataa taacgggaca attagtggat tactttaaac tagaagaaaa attagggtta
     5941 aaaaaccgta gaaaatcaga taaatatgat ataagtaaaa ataaccctaa agaaaataaa
     6001 gaacaacata atcatgatga aataatttta gacactctag ctaaatctca tggaaataca
     6061 aatagacttg catttataat aacacatgga aagggatata aattttatat aggaattata
     6121 gtaatcggtt ttatatttat gtcacttgct cactctggac ttaatcttcc tataattgag
     6181 aagttacatt cattggaaga agtaatagca gtgattggaa tattattttc aataatttat
     6241 atgtggtgtt ttaaaaaggt atttaaaaat tctaatcaaa aagaggaaga aaataaaaag
     6301 atttctttgc gagaaatgct tatccattct gttggagaaa tatcatttgt aattacatgg
     6361 atttttattg catatcttat ttacgatttg ataatattaa ttttaggtgg agatgaatac
     6421 ttagttaaac tagtattatc aacaggtgta ataagtgtat ttataggtgc aggtcttgga
     6481 cttattccag gttgtgggat acaaattgtg cttatgtcat tttatttgaa gggaactata
     6541 ccacttggtg cagtgatagc caactctatt tctcaagatg gagatgcact tttcccactt
     6601 ttagcaatgg ataaaaaatc ttctttatgg gctatgatta ttactactat accagcaata
     6661 cttgtaggta tgatagttta tgcattttta ggttaaatat aattacgaat aaagaagtat
     6721 taaaaaaata ataaagcaca taaatttatt tataagaata gtgaagatta aatataaaaa
     6781 taaaaaattc aatatgaatt aaattattgc ttaaatatta atgagaacat gggagataat
     6841 attattcctc atgttctctc tatttaatta aaggaattat ggaacaaatt tcaagtgata
     6901 ctttctatca aaactcatat ataatatata ttaataaatt aaactataat acgtaataca
     6961 gccagtatat tgatataaaa aacttaggag gagttgtaaa aatgggtaat ttaaaaagac
     7021 agtgtgatgt ttcaagtgga agagaaaaag ctgacattgt actaaaaaat gggacaatca
     7081 taaatgtatt tacagaagag ttaataacag gagatgtagc aatagtagga gacactatcg
     7141 ttggcattgg cgattacaag ggcaatgtag aaattgattg tagcaataaa tatatatcac
     7201 ctggctttat tgatgcacat atgcatattg aatctacaat ggtaatgcca attgaattat
     7261 cgaaaaaatt attaaaatca ggtacgacaa ctatcatagc cgacccacat gagttggtca
     7321 atgtaaaagg agctagtgca atagattttt tattagaatc gacaaaagat ataccactta
     7381 atgtatatat tatggtgcct tcatccgtac ctgcaacaag ttttgaaact aatggagttg
     7441 gtaaatttag tgcaaaagac atggagagtt atgtaaataa tcctagaatt ttaggtttag
     7501 gagaggtaat gtgttttaat gatgttataa attctgaaaa tgaaatcttg gataaactag
     7561 agctttttaa aaataaagtt gtagatggac atgcacctaa tataaatggt aaatcacttc
     7621 agacatatgt atgtgcagga atagaaaatg accatgaatg tataactttt gatgaagtat
     7681 atgaaaaatt gagagcagga ttaaaaattt taataagaga aggaagcgca gcaaaaaatt
     7741 taaagtctat agtaagtggt atgctaaagc ataacttgcc aattgaagaa tttatgtttt
     7801 gcacagatga taagcactta gatgatatag aaaaacaagg tcacataaga tggaatataa
     7861 aatgtgcgat tgatttaggt atggaacctg ttagggctat aaaagttgca acttataatt
     7921 ctgcaaaagc atatgggtta aggaaaattg gagcaatagg tgcgggttat aaggcagata
     7981 ttgttgtatt gaatgattta gacaaaatgg aagtggatag tgtatataaa gatggtaatt
     8041 tggtaaacga agagatgttt tctaattaca attatgagat taaagataaa gaattgctta
     8101 atacagtcaa gtttaagtat attaataaag aaaaaataca gttaaaagta agtgaaaaaa
     8161 attatgtaat ggagattgta ccttatcaaa ttttgacaaa taaggtatat gaatctttac
     8221 catgtgcaga tggatatttt gttccaaata aagagtattc aaaactttgt gttgttgaga
     8281 gacatagaat gactggaaat gtagcaattg cttcactaaa aggatttggc ataaaaaatg
     8341 gagcaattgc tactactgtg gcccatgatt ctcataatat tatagttgca ggggataatg
     8401 atgatgatat tctagtagct ataaattact taaaggaaat acaaggtggt tatgtaattg
     8461 tatcaaatgg aaaagttctt gcacacctaa gtcttcaagt agctggatta attagtactt
     8521 ttacagctga agaagtacaa gaaattactg ataatatgtt ggagatagca agaaaaatgg
     8581 gagttccaga gtatgtagac ccttttatta cactttcttt tatggcactt ccagttgttc
     8641 cacaaataag acttacagat ttaggtctat ttgatgttga ggaatttaaa tttatataga
     8701 taatataaaa gtaataataa atgaggcttt ctcaaaatag ggataagtct ctttttattg
     8761 ttgaaatgat gaaaatatat ttgatttcat acaaaaaaga gcatctaatg aactaaaaat
     8821 tttattttta gatatcctta ttttaattaa tctatcattt aaccttgttt taagcataga
     8881 tatcttaata aaactatttt cagtctattt tagaatata
//
LOCUS       DAMJYN010000121         8872 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.126, whole genome shotgun sequence.
ACCESSION   DAMJYN010000121 DAMJYN010000000
VERSION     DAMJYN010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8872)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8872)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8872
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.126"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            100..1701
                     /locus_tag="PC466_003327"
     CDS             100..1701
                     /locus_tag="PC466_003327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp11"
                     /protein_id="HDF2770680.1"
                     /translation="MKMNKKILSLGLAVSLILVNFKSVNASSVVEKIYGKDRYETAAK
                     IADRQTYETVILVNTEKSLADGLSASGLSGATKAPILFTQQNKIPADTNRCLKNIKKA
                     YIIGTEDTISKSVEKELDSKNIEVKRIGGEDRLKTSYLIAKEIATIKKVDKVLLTNAY
                     SGEADAMSVSSVATRDGAPIILTDGKSVPFDVKNIQSYCIGSEEIMSNPLVKNTNSVR
                     IEGTDRFETNKNVIDYFFNSADGFYVSDGYQLVDAIAAAPLTKNSPMVLVNDGSDKTV
                     LEGAKNITSVGEINEKVIQQCINASKSNGQPPTITVGSTEIYKGEKFDTGKLNIVAKD
                     NTGKVLPIEVDGFIDTNRVGTYILTLKATDEWGKSTGKRVEIKVLDDKSYDYNSPEFK
                     KMVSTEMYNLINSYRKEKGKEPLVVSSRLEGMANAWSKYMMDKKVFAHYIDGKNAPQV
                     FSEFGMRSEENIAYIYIDSKNVQTTQDAKNLAKAIFEVWKKSPEYNANMLSDEFYSTG
                     FGLYILSDGQVHATQEFLNGNEGSL"
     gene            1920..3509
                     /locus_tag="PC466_003328"
     CDS             1920..3509
                     /locus_tag="PC466_003328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp12"
                     /protein_id="HDF2770681.1"
                     /translation="MKVNKRVLSIGLTISLIMAGAPNINALSSIEKIQGKDRYETAAK
                     IAQKQTYENVVLVNTDNTLADGLSASGLAGTVKAPILLSQRNSIPSDTEKMLKDVKKV
                     YIIGTEDSIGKSVENELKQKGIEVKRIGGNDRIETSYLIAKEIASIKPIDKVFITNGY
                     TGEADAMSASSVASRDGSPIILTNGKNVPFEKKEGVQCYALGSEEIISNDLVKKTNAV
                     RLAGEDRFETNKKVIKHFYSSAKEFYLSKGYQLVDAVAGSSIAKNAPIVLVDGNSDKS
                     VLRSADKITALGGIDEKTLEQCLSASSLDASAPTITVGNLNIYQGDKFDISKLNIVAK
                     DSNGNDLTPELIGNIDTDKVGKYKVTIKATDIGGKTTSISVEVNVLEYKTNDMNSSEF
                     KRMVSSEMYSLVNSYRKEKGKEPLQVSKNLEGLSNSWSKYMADKGQFSHVINGKKSVE
                     VFTGYGLRSEENIAFVPLVTKSTYTTKDAREVANVIFTVWKKSDKYNENMLNSDFVYT
                     GFGLYILPNGEVYATQEFLNK"
     gene            3735..6011
                     /gene="slpA"
                     /locus_tag="PC466_003329"
     CDS             3735..6011
                     /gene="slpA"
                     /locus_tag="PC466_003329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-layer protein SlpA"
                     /protein_id="HDF2770682.1"
                     /translation="MNKKNIAIAMSGLTVLASAAPVFAAEDMSKVETGDQGYTVVQSK
                     YKKAVEQLQKGLLDGSITEIKIFFEGTLASTIKVGAELSAEDASKLLFTQVDNKLDNL
                     GDGDYVDFLISSPAEGDKVTTSKLVALKNLTGGTSAIKVATSSIIGEVENAGTPGAKN
                     TAPSSAAVMSMSDVFDTAFTDSTETAVKLTIKDAMKTKKFGLVDGTTYSTGLQFADGK
                     TEKIVKLGDSDTINLAKELIITPASANDQAATIEFAKPTTQSGSPVITKLRILNAKEE
                     TIDIDASSSKTAQDLAKKYVFNKTDLNTLYRVLNGDEADTNRLVEEVSGKYQVVLYPE
                     GKRVTTKSAAKASIADENSPVKLTLKSDKKKDLKDYVDDLRTYNNGYSNAIEVAGEDR
                     IETAIALSQKYYNSDDENAIFRDSVDNVVLVGGNAIVDGLVASPLASEKKAPLLLTSK
                     DKLDSSVKAEIKRVMNIKSTTGINTSKKVYLAGGVNSISKEVENELKDMGLKVTRLAG
                     DDRYETSLKIADEVGLDNDKAFVVGGTGLADAMSIAPVASQLRNANGKMDLADGDATP
                     IVVVDGKAKTINDDVKDFLDDSQVDIIGGENSVSKDVENAIDDATGKSPDRYSGDDRQ
                     ATNAKVIKESSYYQDNLNNDKKVVNFFVAKDGSTKEDQLVDALAAAPVAANFGVTLNS
                     DGKPVDKDGKVLTGSDNDKNKLVSPAPIVLATDSLSSDQSVSISKVLDKDNGENLVQV
                     GKGIATSVINKLKDLLSM"
     gene            6247..8592
                     /gene="secA"
                     /locus_tag="PC466_003330"
     CDS             6247..8592
                     /gene="secA"
                     /locus_tag="PC466_003330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HDF2770683.1"
                     /translation="MSVLDAILDKADEQEIKKLNLIVDKIESLEKDMEIKENEQLKEM
                     TNTFRLRLDKGESLDDILPEAFAVVREVSKRVLGMRQYKVQLIGGIVIHQGKIAEMKT
                     GEGKTLVEVAPVYLNALTGKGVHVITVNDYLAERDKELMRPVYEFLGLTVGVILSNQD
                     PSIRKEQYKCDITYGTNSEFGFDYLRDNMVPDLSHKVQRELNFAIVDEIDSILIDEAR
                     TPLIIAGDGDEDLKLYELANNFVKTVKEEDFEMDRKDKTIALTASGISKAESFFGITN
                     LTDIKNIELYHHINQALRGHKLMEKDVDYVISNGEVMIVDEFTGRVMDGRRYTDGLHQ
                     AIEAKEGVEIKNESKTMATVTYQNFFRLYEKLSGMTGTAKTEEGEFESIYKLNVVQIP
                     TNRPVIRADLHDKVFKTEEEKYSAVVEEIIRIHKTRQPILVGTVSVEKSEKLSKMLKK
                     QGIKHQVLNAKQHDKEAEVISKAGKLDAITIATNMAGRGTDISLGAGDKEEEEKVKNL
                     GGLYVIGTERHESRRIDNQLRGRSGRQGDPGTSRFFVSLEDDVIKLYGGKTIEKLMKR
                     TSSKENTAIESKALTRAIERAQKGVEGKNFEIRKNVLKYDDTINEQRKVIYNERNKVL
                     NDEDIKEDIQKMVKDIIQEAGETYLIGRKRDYYGYFKHLYSTFMPADTLLIPGVDKKS
                     VQEIIDSTYEISKRVYDLKKMMIGIDKVAELEKTVLLKVVDQYWIDHIDAMEQLRQYI
                     GLKSYAQKDPFKEYALEGYDMFEALNKNIREATVQYLYKFN"
BASE COUNT         3657 a          934 c         1707 g         2574 t
ORIGIN      
        1 ttcatatcat atatactcta taatatatgg aaaataaaga gaaaataaat agaaaataat
       61 cacaatataa atataaaata taaaaatcat cagggggata tgaaaatgaa caaaaaaata
      121 ttatcattag gtctagcagt atcattaatc ttagtaaact tcaaaagtgt aaatgcatca
      181 tcagtagtag aaaaaatata cggtaaagat agatatgaaa cagcagcaaa gatagctgat
      241 agacagactt atgaaacagt aattttagta aatacagaaa aatcacttgc agatggatta
      301 agtgcaagtg gattatcggg agctacaaaa gctccaatac tatttacaca acaaaataag
      361 ataccagcag acacaaatag atgtctaaaa aatatcaaaa aagcatatat aataggtaca
      421 gaagatacta taagtaaatc agtagaaaaa gaactagatt ctaaaaatat agaagtcaaa
      481 agaattggtg gagaagatag actaaaaaca agctatttaa tagctaaaga aatagcaact
      541 ataaaaaaag tggataaagt actattaact aacgcatata gtggagaagc agacgcaatg
      601 agtgtatcat cagtagctac tagagatgga gctccaatca tacttacaga tggaaagagt
      661 gtgccttttg atgtaaaaaa tattcaatca tattgtatag gttcagagga gataatgagt
      721 aaccctctag ttaaaaatac aaactcagta agaatagaag gaactgaccg atttgaaact
      781 aacaaaaatg taatagacta cttttttaat agtgcagatg gattctatgt atcagatgga
      841 taccaattag tagatgcaat agcagctgca ccacttacta aaaactctcc aatggtacta
      901 gtaaatgatg gaagcgataa aactgtatta gaaggagcta agaatataac ttctgtaggt
      961 gaaataaatg agaaggtaat acaacagtgt ataaatgctt caaagtcaaa tggacaacca
     1021 ccaacaatta cagttggaag tacagagata tataagggtg aaaagtttga cactggcaag
     1081 ttaaacatag tggctaaaga taacactggg aaggtattac caatagaagt tgatgggttt
     1141 atagatacaa atagagtagg tacatacata ttgacattaa aagctacaga cgaatgggga
     1201 aaaagtacag gaaaaagagt agaaataaaa gtgttggatg ataaatccta tgattacaac
     1261 agcccagaat ttaaaaaaat ggtatctact gaaatgtata acttaatcaa ttcctataga
     1321 aaagaaaaag gcaaagagcc tttggtagta tctagtaggc tagaaggtat ggcaaatgca
     1381 tggtctaagt atatgatgga taaaaaagta tttgcacatt atatagatgg aaaaaatgct
     1441 ccacaagtat tttctgagtt tggaatgaga agtgaggaaa atatagcata tatttatata
     1501 gattctaaga acgttcaaac gacacaagat gcaaaaaact tggcaaaggc tatatttgaa
     1561 gtgtggaaga agtctccaga gtacaatgca aacatgctta gtgatgagtt ctatagtact
     1621 ggatttgggc tttatatatt atctgatggt caagtgcatg ctactcagga gtttttaaat
     1681 ggcaatgaag gtagtttgta aaaaattcca taaatcttgt ttttttgtta atttactgat
     1741 attataaaat gaaaatcaca tctaaagtac tttttgtaat ctgttttgtt attgctttac
     1801 aggctatggt attttaggtg ttttttgttt tagtagttta tagattttga gggaatcact
     1861 actgaggatg taatttatga ttagctgaat tatataaaaa aattagtagg aggagttcga
     1921 tgaaggtaaa taagagagta ttatcaatag gattgacaat atcattaata atggcaggag
     1981 caccaaatat caatgcactt tcgagcatag aaaagataca agggaaagat agatatgaga
     2041 cagctgccaa aattgcacag aaacaaacat atgaaaatgt agtattagta aatacagata
     2101 atacactagc tgatggatta agtgcaagtg gattagcagg aacagttaaa gcacctatat
     2161 tattatcaca aagaaacagt ataccatcag acacagaaaa aatgttaaaa gatgtaaaga
     2221 aggtttatat aataggaact gaagattcaa taggaaaatc agttgaaaat gaattaaagc
     2281 aaaaaggaat agaagttaaa agaataggtg gtaatgatag aattgaaaca agttatctta
     2341 tagcaaaaga aatagcttca ataaaaccta tagataaggt ttttataact aatggttata
     2401 caggtgaagc agatgctatg agtgcgtcat cagtagcatc aagagatgga tcacctataa
     2461 ttttaactaa tggtaaaaat gttccatttg agaaaaaaga aggtgtgcaa tgttatgctc
     2521 ttggttcaga ggagataata agtaatgatt tagttaaaaa aactaatgca gttagattag
     2581 ctggagaaga tagatttgag actaataaaa aagttataaa acatttttat agttcggcaa
     2641 aagaatttta tctttctaaa ggttatcaat tagtagatgc agttgctggt tcttctatag
     2701 caaaaaatgc acctattgta ttagttgacg gaaatagtga taagtctgta cttagaagtg
     2761 ctgataagat tacagcacta ggaggaatag atgaaaagac actagaacaa tgtttaagtg
     2821 catcatcact ggatgcaagt gcaccaacaa taactgttgg aaatttaaat atttatcaag
     2881 gtgataagtt tgatataagt aaactgaata tcgtagcaaa ggatagcaat ggtaacgatt
     2941 tgacaccaga gcttatagga aatattgata ctgataaggt gggtaaatac aaagttacta
     3001 taaaagctac tgatattggt ggaaagacta catcaataag tgtagaagta aatgtacttg
     3061 aatataagac taatgatatg aatagtagtg agtttaaaag aatggtttct agtgaaatgt
     3121 atagtttggt aaattcatat agaaaagaaa aaggtaaaga gccattacaa gtttctaaaa
     3181 acttagaagg actttctaat tcctggtcta agtacatggc agataaaggt cagttttcac
     3241 atgtaataaa tggtaagaaa tctgttgaag tatttactgg atatggcttg agaagtgaag
     3301 aaaatatagc ttttgtacca cttgttacaa aaagtactta tacaacaaag gatgctagag
     3361 aagtagcaaa tgtaatattt acagtttgga aaaagtcaga taaatataat gaaaatatgt
     3421 taaatagtga ttttgtatat actgggtttg gattatatat attgcctaat ggagaagtgt
     3481 atgctacaca agaattttta aataagtaat ttaaataagt aaaatcaaat tttttaagtt
     3541 attaaatatt ggagtttaag ggtataaaaa ctcatatgct tgggaaaaat aataatttca
     3601 aaaaaatgac ttgcaaaaag aataaaaatg gattattata gagatgtgag aaatattagg
     3661 aatatatgga tgattattct atgtacataa tgaagagatg taattttaat ataatgttgg
     3721 gaggaattta agaaatgaat aagaagaata tagcaatagc tatgtcagga ttaacagtat
     3781 tagcttctgc agcacctgtg tttgcagcag aagatatgtc gaaagttgag actggtgatc
     3841 aaggatatac agtagtacag agcaagtata agaaagcagt tgaacaatta caaaaagggt
     3901 tattagatgg aagtataaca gagattaaaa ttttctttga gggaacttta gcatctacta
     3961 taaaagtagg agctgagctt agtgcagaag atgcaagtaa attattgttt acacaagtag
     4021 ataataaatt agacaattta ggtgatgggg attatgtaga tttcttaata agctctccag
     4081 cagagggaga taaagtaact acaagtaaac ttgttgcatt aaaaaattta acaggtggaa
     4141 ctagtgcaat aaaagtagct acaagtagta ttattggtga agtcgaaaat gctggtactc
     4201 cgggagcaaa aaatacagct ccaagtagtg ctgcagttat gtctatgtca gatgtatttg
     4261 atacagcttt tacagattca actgaaactg ctgtgaaact tactataaaa gatgctatga
     4321 aaactaaaaa gtttggttta gttgatggaa ctacttattc aacaggtctt caatttgcag
     4381 atggaaaaac agaaaaaatt gttaaattag gagatagtga tactataaat ttagccaaag
     4441 aattaataat aacacctgca agtgcaaatg atcaagctgc gactattgag tttgctaaac
     4501 caacaacaca atctggaagc ccagtaataa ctaaacttag aatattgaat gcaaaagaag
     4561 agacaataga tattgatgct agttctagta aaacagcaca agatttagct aaaaaatatg
     4621 tatttaataa aacagattta aatactcttt acagagtatt aaatggggat gaagcagata
     4681 ctaatagatt agtagaagaa gttagtggaa aatatcaagt ggttctttat ccagaaggaa
     4741 aaagagttac aactaagagt gctgcaaagg cttcaattgc tgatgaaaat tcaccagtta
     4801 aattaactct taagtcagat aagaagaaag acttaaaaga ttatgtggat gatttaagaa
     4861 catataataa tggatattca aatgctatag aagtagcagg agaagataga atagaaactg
     4921 caatagcatt aagtcaaaaa tattataact ctgatgatga aaatgctata tttagagatt
     4981 cagttgataa tgtagtattg gttggaggaa atgcaatagt tgatggactt gtagcttctc
     5041 ctttagcttc tgaaaagaaa gctcctttat tattaacttc aaaagataaa ttagattcaa
     5101 gcgtaaaagc tgaaataaag agagttatga atataaagag tacaacaggt ataaatactt
     5161 caaagaaagt ttatttagct ggtggagtta attctatatc taaagaagta gaaaatgaat
     5221 taaaagatat gggacttaaa gttacaagat tagcaggaga tgatagatat gaaacttctc
     5281 taaaaatagc tgatgaagta ggtcttgata atgataaagc atttgtagtt ggaggaacag
     5341 gattagcaga tgccatgagt atagctccag ttgcatctca attaagaaat gctaatggta
     5401 aaatggattt agctgatggt gatgctacac caatagtagt tgtagatgga aaagctaaaa
     5461 ctataaatga tgatgtaaaa gatttcttag atgattcaca agttgatata ataggtggag
     5521 aaaacagtgt atctaaagat gttgaaaatg caatagatga tgctacaggt aaatctccag
     5581 atagatatag tggagatgat agacaagcaa ctaatgcaaa agttataaaa gaatcttctt
     5641 attatcaaga taacttaaat aatgataaaa aagtagttaa tttctttgta gctaaagatg
     5701 gttctactaa agaagatcaa ttagttgatg ctttagcagc agctccagtt gcagcaaact
     5761 ttggtgtaac tcttaattct gatggtaagc cagtagataa agatggtaaa gtattaactg
     5821 gttctgataa tgataaaaat aaattagtat ctccagcacc tatagtatta gctactgatt
     5881 ctttatcttc agatcaaagt gtatctataa gtaaagttct tgataaagat aatggagaaa
     5941 acttagttca agttggtaaa ggtatagcta cttcagttat aaataaatta aaagatttat
     6001 taagtatgta atataaatat aataatataa aaaggcttct tatatgagaa gtctttttat
     6061 attatgtttt cgaatacaaa aaaagagact aaatttagtc tcttttttat gtgagaaata
     6121 cttaaatata taaagatgta atttatttaa gtatgattat tatactatac aataaaataa
     6181 ttgtctacta ttctataatt ttaaggtata ataataattg tatgataaaa gaggaggtca
     6241 aaaaatatgt cagttttaga tgcaatctta gataaagcgg atgaacaaga aattaaaaaa
     6301 ttaaatttaa tagtagataa aatagaatct ttagaaaaag atatggaaat caaagagaat
     6361 gaacaattaa aagaaatgac aaatactttt agacttagat tagacaaagg tgaaagtttg
     6421 gatgatatac ttccagaagc atttgctgtt gttagagagg tctcaaaaag agttttagga
     6481 atgcgtcaat ataaagttca gttaattgga ggtatagtaa ttcatcaagg aaagatagct
     6541 gagatgaaga ctggtgaggg gaaaacttta gttgaggtag ctccagtata tctaaatgct
     6601 ttaacaggaa aaggtgtaca tgtaattaca gtaaatgatt atttggcaga acgtgataaa
     6661 gaacttatgc gtccagtata tgaattttta ggattgactg taggtgtaat tttatctaac
     6721 caagacccaa gtataagaaa agaacaatat aaatgtgata taacttatgg aacaaatagt
     6781 gaatttggat ttgactattt aagagataat atggtgccag atttgtctca taaagtacaa
     6841 agggaactaa actttgccat agtagatgag atagactcaa tattaataga tgaagctaga
     6901 actccactta ttattgcagg agatggtgat gaagatttaa aactttatga gttagcaaat
     6961 aactttgtaa aaactgttaa agaagaagac tttgagatgg atagaaaaga taaaactata
     7021 gcattaacag caagtggtat aagcaaagct gagtcatttt ttggtataac aaaccttact
     7081 gatataaaga atatagaatt atatcatcat ataaatcaag ctttaagagg tcataagctt
     7141 atggaaaaag atgttgacta tgttatctca aatggagaag taatgatagt tgacgaattt
     7201 acaggaagag taatggatgg tagaagatat acagatggac ttcaccaagc tatagaagcc
     7261 aaagaaggtg ttgagataaa gaatgaatct aaaactatgg ctactgtgac ttatcaaaat
     7321 ttcttcagac tatatgaaaa actttctggt atgactggta ctgcaaagac agaagaaggg
     7381 gaatttgagt caatctataa attaaatgtt gtccaaatac caactaatag accagttatt
     7441 agagctgatt tgcatgataa ggtatttaaa acagaagaag aaaagtatag tgctgttgta
     7501 gaagaaataa taaggataca taagactaga cagccaatac tcgtgggaac agtttctgtt
     7561 gaaaaatctg agaagttatc taaaatgctt aagaagcaag gtattaagca tcaagtctta
     7621 aatgctaaac aacatgataa agaggcagag gtaatttcta aagctggtaa attagatgct
     7681 ataacgattg ctacaaatat ggcaggtaga ggtacggata tttctctagg tgcaggagat
     7741 aaagaagaag aagaaaaagt taaaaattta ggtggtcttt atgttatagg aacagaaaga
     7801 cacgaatcaa gaagaattga caatcagctt agagggcgtt ctggtcgtca aggagaccca
     7861 ggtacatcaa gattttttgt aagtcttgaa gatgatgtaa taaagcttta tggtggaaaa
     7921 actatagaga aacttatgaa gagaacaagt tcaaaggaaa atacggctat tgaaagtaaa
     7981 gcacttacaa gggctataga aagagcacaa aaaggtgtag aaggtaagaa ttttgaaata
     8041 agaaaaaatg ttcttaaata tgatgatact attaatgagc aaagaaaggt tatatataat
     8101 gaaagaaata aagtgttaaa tgatgaagat ataaaagaag atattcaaaa aatggttaaa
     8161 gacatcatac aagaagcagg agaaacttat ttaattggaa gaaaaagaga ttattatgga
     8221 tattttaaac atttatatag tacatttatg cctgcagata cattactaat acccggtgta
     8281 gataaaaaaa gtgtccaaga gataattgat agcacatatg aaatttcaaa aagggtttat
     8341 gacttgaaaa agatgatgat tggtattgat aaagttgcgg agttagaaaa aacagtactt
     8401 ttaaaagtgg ttgatcaata ctggatagat catatagatg ctatggaaca gttaagacag
     8461 tatataggtc ttaaatctta tgctcaaaaa gatccgttta aagaatatgc tttagaagga
     8521 tatgatatgt ttgaagcttt aaataaaaat ataagggaag caacagtaca atacttatat
     8581 aaatttaact aaaaaagttc atgtaatttt tattaaatga aaaataaaat attttgattc
     8641 tttatattgt aattacaatt aaataattaa ggaatacaaa tgaaaaagaa gctgaaaatc
     8701 agcttctttt tctgtgtgag aaatacggaa aaaagagatg cttgaaattt ctttcttcca
     8761 tttaatatta tactataaag aagatgaaaa gtctattagt tataaactgg attattaaaa
     8821 aaaattacaa ttttgttact tttttgtata cataaatatt aaaaaaataa aa
//
LOCUS       DAMJYN010000122         8777 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.127, whole genome shotgun sequence.
ACCESSION   DAMJYN010000122 DAMJYN010000000
VERSION     DAMJYN010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8777)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8777)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8777
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.127"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            283..1299
                     /gene="gap"
                     /locus_tag="PC466_003331"
     CDS             283..1299
                     /gene="gap"
                     /locus_tag="PC466_003331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011948756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HDF2770684.1"
                     /translation="MKIKVGMNGFGRIGRAVLRIAQEELGDNIEIVAINARATTESLA
                     HLFTYDSCYGTFRGEVEAKDEDTLVVNSKEIKILRYSDPEELPWKELGVDIVIESTGL
                     FTQREKAEKHIKAGAKKVIITAPGKNEDITIVIGVNEKEYDNQKHNIISNASCTTNCL
                     APFAKVLDEKFGIVKGLMTTVHSYTNDQRILDKSHKDLRRARAAAESIIPTTTGAAKA
                     VSRVLPQLEGKLNGFSLRVPTPTVSLVDLVCELKENVTSEQVNSVLKDAAEGELKGVL
                     GYCDKPLVSIDYKGDSRSSIIDALSTMVIEDNMVKVVSWYDNEWGYSSRTVDLVKYVA
                     EKLK"
     gene            1694..2863
                     /locus_tag="PC466_003332"
     CDS             1694..2863
                     /locus_tag="PC466_003332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770685.1"
                     /translation="MEKLTDRRQVKAVSMETFIFLILLVVGFGYVGSIMGAGMMFKVI
                     MSTAHALLLETVFLIMAMAVLAGALSALLSEFGVIALINKIFAVFMKPLYGLPGASIA
                     GAITTYLSDNPAIIPFAKDKTFTQYFKQYQVPALCNLGTAFGMGLILTTFMISQGTEY
                     VLPALIGNLGAIIGSVISVRIMLTFTKKFYKYNPEEDKATGTLEKKDEFREIREGNVF
                     QRALDAILEGGKMGVDMGMAIIPGVLVVCTLVMLLTFGPSTDPVTGQEVYTGAAYEGI
                     KLLPVIGDKLGFILEPLFGFTSPEAIAFPITSLGAVGAAMSLVPEFIKSGAITPNDIA
                     VFTAMGMCWSGYLSTHIGMMDALNARQLAGKAILSHTIGGLCAGAAAHFIFTLVG"
     gene            3244..7497
                     /locus_tag="PC466_003333"
     CDS             3244..7497
                     /locus_tag="PC466_003333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyacyl-CoA dehydratase"
                     /protein_id="HDF2770686.1"
                     /translation="MDELFHIGIDVGSTTVKVVVLNNSNNIVHKEYRRHYSDVKKSVK
                     EVLNGIYEKLGDINTTIIITGSGGIGISKKLGVKFVQEVISSTKSIEYFHPETDVVIE
                     LGGEDAKITYLSGGIDQRMNGICAGGTGAFIDQMASLLKTDASGLNELAKGYNVIYPI
                     ASRCGVFAKTDIQPLINDGANQTDIAMSIFNAVVVQTVSVLSCGRKIEGNVAFLGGPL
                     YFLSELREAFKRVLDLKDENIIFPENAQLYIAIGAGLLSVDEDNIQLKSLIEKLDSIK
                     NIEDGEVNLLEPLFKDKNEYEEFSRRHEKEKISYVDINSIKSNCYLGIDAGSTTTKAA
                     LIDEDGRLVYSYYNSNEGNPLKTTIKVINEVYDILPKNIKILSSTVTGYGEGLIKKAL
                     KIDNGEIETIAHYKAAKFFNKDVDFILDIGGQDMKCLKIKDGVIDNIILNEACSSGCG
                     SFLETFASSLSMTIEEFAHEGIYSQNPVDLGSRCTVFMNSRVKQAQKEGASVGDISAG
                     LSYSVIKNALFKVIKIRDLNEIGNNIVVQGGTFYNDLVLRSFEKLIGKNVIRPNISGI
                     MGAFGSALIAKEKYESGYKTSLLSKEELNNIKLEASVTRCKGCSNHCLLTINKFSDNE
                     IFISGNRCEKGEAIYGDKKIGLEKKKPINLFKYKYNRIFRYKPLEKEEAKNGEIGIPR
                     VLNMYEDYPFWFTFFNAMGFRVVLSDRSSKQLYETGITSIASETVCYPGKLVHGHIEN
                     LIAKGIKNIFYPSVTNENKEDSNADNYYNCPVVISYSEVIKNNVENIRNKNINYINPF
                     ISLNDKEKLKKRLYDELSRHFSDIKITKEEVNHAVDKATDEQNLFKMEIQAAGERALK
                     EIKERNMKGIVLCGRPYHIDPEINHGMPELINSLDMAVLTEDSICHLANVQRPLRVVD
                     QWVYHSRLYKAASFVRDKNYLELVQLNSFGCGLDAVTTDQVQEILNEKSKIYTIIKID
                     EGNNLGAAKIRMRSLKAAMFERESKNIDVKNIKVNRIQYAKNNQITNKHTILAPQMSP
                     IHFQFLEKAVNLSGYNIEILKDTDSSVIEEGLRYVNNDACYPAIIVVGQLITALKSGK
                     YDLNNTSVTITQTGGGCRATNYIGFLRKAIYDAGFKDVPVIALSVNGIEDSGIMDNIS
                     LKLINRLFMSVVYGDLLMKVLYRVRPYEKVTGSANALYEKWVDICKSSLVKAKISVFT
                     RNIKDIVKEFDNLEILDIKKPKVGLVGEILVKFHPIANNNLVDILEREGAEAVVPDLT
                     NFFLSCAFNTIYKHTHLEGSRKSRMIGEAFIYITGIYQRVYKKALDKSERFYAPANIK
                     NVAKSTEPVVSLGNQTGEGWLLTGEMVELLNEGVENIICMQPFGCLPNHIIGKGSIKE
                     LKRLYKNANIIPIDYDPSASEVNQLNRIKLMLSKAFKNI"
     gene            7646..8140
                     /locus_tag="PC466_003334"
     CDS             7646..8140
                     /locus_tag="PC466_003334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HDF2770687.1"
                     /translation="MSLVYDVYKSKLGNLYILSEDGFIVSVYIGDEKFNNLKNECIKK
                     GIDIKISKEDLKEAISQIDDYFNGKRKVFNLNIRIEGTEFQKSVYREMLKIPYGETLC
                     YSDIARNINNPKSVRAIGQASKSNKIPIIIPCHRVVGKKNIGGYMGNHSDLKEILLNL
                     ERQS"
     gene            8256..8633
                     /locus_tag="PC466_003335"
     CDS             8256..8633
                     /locus_tag="PC466_003335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="monooxygenase"
                     /protein_id="HDF2770688.1"
                     /translation="MCDKVIASKYHEKGFNCAESVIKAYNEEFNTDIPVCLGSGLGSG
                     CGVASLCGAVNASNIIIGYVKGRNHEDESTKAKVYAKDLTTTVRKEYGSELCIDLKKD
                     LVACREIMDFAYDSLKETLKKEL"
BASE COUNT         3551 a          913 c         1599 g         2714 t
ORIGIN      
        1 gatatattat ttttaaaaat aagtatagtt taaaaattca aaaaaaagat ggcaaaatat
       61 gtcccaaggg acattgagta aaataaatga tttcagctta tttacactaa aaagtacata
      121 ctaaatgagg ggtgaaataa agaaaaatga tatactaatt gtcttttgat aataaaaaaa
      181 catggaattt gattatttaa tcaagaaaaa gtattgaaca aatgatttat ttagtgtaca
      241 ataatcatgt aaaaacatag taatggaggg agacatttca taatgaaaat taaggtagga
      301 atgaacggat ttggaagaat aggaagagct gtattaagaa tagctcaaga agaattagga
      361 gataatatag aaattgtagc cataaatgca agagcaacaa cagaatcttt ggcacattta
      421 tttacatatg attcatgcta tggaactttt agaggtgaag tagaggcaaa ggatgaagac
      481 actctagtag taaactctaa agagataaaa atattaagat atagtgaccc agaagaatta
      541 ccatggaaag aactgggggt tgatatagta atagaatcaa caggattatt tacacaaaga
      601 gaaaaggcag aaaaacatat taaagcagga gcaaaaaaag taattataac agctccagga
      661 aaaaatgaag atataactat agttatcgga gttaatgaga aagaatatga taatcaaaag
      721 cacaatataa tttcaaatgc atcttgtact acaaattgtc tagctccttt tgctaaagta
      781 ttggacgaaa aatttggtat agtaaaaggg ttaatgacta cagtacattc atatactaac
      841 gatcaaagaa tattagataa aagccataaa gatttgagaa gagcaagagc agcggctgaa
      901 tctataatac ctaccactac aggagcagca aaagctgtgt caagagtact accacaatta
      961 gaaggaaaat taaatggttt ttcacttaga gtaccaacac caacagtttc acttgttgat
     1021 ttagtgtgcg aacttaaaga aaacgttaca tctgagcaag ttaactctgt gttaaaagat
     1081 gctgctgaag gagaattaaa aggtgtttta ggatattgtg acaagccact tgtttctata
     1141 gattataaag gagattcaag atcatctatt atagacgctc tatccacaat ggttatagaa
     1201 gacaatatgg ttaaggtagt ttcttggtat gataatgaat ggggatattc ttcaagaact
     1261 gttgacttag taaaatatgt agctgaaaaa ttaaaataat atatatttct taaagcaaat
     1321 tttaaaaaaa ttttttgaaa aaattatata aaactaaaaa aaaagattat gaaaaatatt
     1381 gaaggaaaaa ttttttcata atcttttttc tttcatgcaa aaagatacaa gttacaactt
     1441 atatttgcat attaggtcgt tagagaagta tatatatatt tagtaaggaa tcatactttt
     1501 tataaaatga aagataagat gtcgaaaact tgcataaatc tgaaaaattt ttattattaa
     1561 aatactgatt ttcattttaa aaatgataaa aaaatgacaa ataaagttgc aaatagtaat
     1621 acttataagt ataattaaaa aagagaaaag gttttgttaa actttataac aaaaaaagaa
     1681 gggatgattc aaaatggaga agttaacaga caggagacag gttaaggcag taagcatgga
     1741 aaccttcatt ttcctaatat tactagtagt tggttttggg tatgttggta gtattatggg
     1801 agcaggaatg atgttcaaag taataatgag tacagcacat gctttactat tggagacagt
     1861 tttcttaatt atggctatgg cagttcttgc aggcgcatta agcgcactac tttcagagtt
     1921 tggagtaata gcgttaatta ataaaatttt cgctgtattt atgaagcctt tatatggact
     1981 acctggtgct agtatagcag gagctataac aacttattta tcagataatc cagctattat
     2041 accttttgct aaagataaaa cattcacaca gtattttaaa caataccaag ttccagcatt
     2101 atgtaactta ggaacagcct ttggtatggg acttatctta acaacattta tgatttctca
     2161 aggtacagaa tatgtacttc cagcattaat tggtaattta ggtgcaatta taggtagcgt
     2221 cataagtgtt agaataatgt tgacatttac taagaagttt tataaataca atccggaaga
     2281 agataaagca acaggaacat tagagaaaaa ggatgaattt agagaaatca gagaaggaaa
     2341 tgtatttcaa agagctttag atgcaattct tgaaggtggt aaaatggggg tagatatggg
     2401 aatggctata attcctggag tcctagtagt atgtacattg gtgatgttat taacttttgg
     2461 accatctaca gaccctgtta caggtcaaga agtttataca ggagctgcat atgaaggaat
     2521 aaaattactt ccagttattg gagataaact tggatttata ttagaaccat tatttggatt
     2581 tacatcacca gaggcaatag cattccctat aacttcattg ggagctgttg gtgcagcaat
     2641 gtctctagtt ccagagttta taaagtcagg agctataact cctaatgata tagcagtatt
     2701 tacagctatg ggtatgtgtt ggagtggata tttaagtaca catattggta tgatggatgc
     2761 attaaatgct agacagttgg caggtaaagc tattctttct catacaatag gtggtttatg
     2821 tgcaggagca gcagctcact ttatatttac actcgtagga taaacgtaat cagctaagat
     2881 aaaaaataat atacaaaaaa atggttgttg atatgtaata agaatttaca tatcaacaac
     2941 catttttttc tgactaaaga taatttataa tacataaaca ttaagtggat attagactta
     3001 agttatattt atgtaaaaag taacaaaaat ctgtagaaat ttatgacaaa atttagtaca
     3061 ctaactatat gttcttattt aaaatttaag gttagaatta ggaattacct agtagagtaa
     3121 gctttgatta ataaaagaat cataaaataa aaatattagt cataaagatt ataaataact
     3181 tacttaaaat aaagccatag aacttacaaa aattaaaaaa gcatataaat atggaggggt
     3241 acaatggatg aattatttca tataggaatt gatgtaggtt ctacaacggt gaaggttgtg
     3301 gtacttaata atagtaataa tatagttcat aaagaatata gaagacatta ttctgatgta
     3361 aaaaaatcag ttaaagaagt actaaatggt atatatgaaa aattgggaga tataaatact
     3421 accattataa taactggttc aggtggaatt ggaatatcaa aaaaattagg tgtaaaattt
     3481 gttcaggaag ttatatctag tacaaaatca atagagtatt ttcatcctga aactgatgtt
     3541 gtcatagaac ttgggggtga agatgcaaag ataacatatc taagtggagg aatagaccaa
     3601 agaatgaatg gaatatgtgc aggtggcact ggagcattca tagaccaaat ggcatcactt
     3661 ttaaagacag atgccagtgg attaaatgaa cttgctaaag ggtataatgt tatatatcct
     3721 atagcttcaa gatgtggtgt ttttgctaaa acagatattc aacctcttat aaatgatgga
     3781 gccaatcaga ctgatatagc aatgagtatt ttcaatgcag ttgtcgtaca aactgtgagt
     3841 gtcctttctt gtggaagaaa aatagaagga aatgttgcgt ttttgggtgg tccattgtac
     3901 tttttatctg aacttagaga agcatttaaa agagtattgg atttaaaaga tgaaaacata
     3961 atcttcccag aaaatgcaca actttatatt gctattggag caggattatt atcagtagat
     4021 gaagataata tacaactaaa atctctaata gaaaaattgg atagtataaa gaatattgaa
     4081 gatggagaag taaatttatt agaaccttta tttaaagata aaaatgagta tgaagaattt
     4141 tcaagaagac atgaaaaaga aaaaataagt tatgtggaca taaattcaat aaaaagcaat
     4201 tgttatttag gaattgatgc aggctcaact acaactaaag cagcacttat tgatgaggat
     4261 ggaagacttg tatattctta ttataatagc aatgaaggaa atccattaaa aacaaccatt
     4321 aaagttataa atgaagtata tgatatatta ccaaaaaata ttaaaatatt gagttcaact
     4381 gtaactggat atggagaagg tcttattaaa aaagctctta aaatcgataa cggagagata
     4441 gagactatag cacattacaa agctgctaaa tttttcaata aagatgtaga ttttatactt
     4501 gatattggtg gtcaagatat gaagtgccta aaaataaaag atggagtaat tgataatata
     4561 atattaaatg aggcttgttc atcaggttgt ggctcatttt tagagacatt tgcaagttct
     4621 ttatctatga caatagaaga atttgcacat gaaggtattt attctcaaaa tcctgtagat
     4681 ttaggttcaa gatgtactgt atttatgaat tctagagtaa aacaagctca aaaagaaggt
     4741 gcaagtgttg gagatatatc agcagggcta tcttattcag taataaaaaa tgctttattt
     4801 aaagtaataa agattagaga tttaaatgag attggtaata atattgttgt acaaggtgga
     4861 accttttata atgatttggt gcttagaagc tttgaaaaac taattggaaa aaatgtaatt
     4921 agacctaata tttcaggaat tatgggagct tttggttcag cacttatagc taaagaaaaa
     4981 tatgaaagtg gatacaaaac atccttgtta tctaaggaag agttgaataa tatcaagcta
     5041 gaagcaagtg taactagatg taaaggttgt tcaaatcatt gtcttcttac aataaataaa
     5101 ttttctgata atgaaatttt tatttcaggt aatagatgtg agaagggtga agctatttat
     5161 ggtgataaaa aaataggatt agaaaagaaa aaaccaataa atttatttaa gtacaaatac
     5221 aatagaattt ttagatacaa accattggaa aaagaagaag caaaaaatgg ggaaataggg
     5281 ataccaagag tattaaatat gtatgaagat tatccatttt ggtttacttt tttcaatgct
     5341 atgggcttta gagttgtact ttcagatagg tcatcaaaac agttatatga aactggtata
     5401 actagtattg catctgaaac agtttgttat ccaggaaaat tagttcatgg acatatagaa
     5461 aatttaattg caaaaggtat aaaaaatata ttttatccaa gtgtaacaaa tgaaaataaa
     5521 gaggattcaa atgcagataa ttattataat tgtcctgttg taatatcata ttctgaagta
     5581 ataaaaaaca atgtagagaa tataagaaat aagaacataa attatataaa tccatttata
     5641 agtctaaatg ataaggaaaa attgaagaaa agactatatg atgaattatc aagacatttt
     5701 tctgatataa aaataactaa agaagaagtt aatcatgcag ttgataaagc tactgatgaa
     5761 cagaatttat ttaaaatgga gatacaagca gcaggtgaaa gagcacttaa agaaataaaa
     5821 gaaagaaata tgaaggggat tgtgttatgt ggaagaccat atcatataga cccagaaata
     5881 aatcatggaa tgccagagct tataaattca ttagatatgg cagtgcttac tgaagactct
     5941 atatgtcatt tagccaatgt acaaagacca cttagagttg tagaccaatg ggtatatcat
     6001 tcaagattgt ataaagcagc tagttttgta agagataaaa actatttgga acttgttcaa
     6061 cttaattcat ttggctgtgg attagatgca gtaactacag accaggttca agaaatactt
     6121 aatgaaaaat cgaagatata tactattata aagattgacg aaggcaacaa tttaggagca
     6181 gctaagataa ggatgaggtc cttaaaagca gctatgtttg agagagaaag caaaaatata
     6241 gatgtaaaaa atataaaggt aaacaggata cagtatgcta aaaataatca gataacgaac
     6301 aaacatacta tattagcacc acaaatgtct ccaatacatt tccaattcct tgaaaaagct
     6361 gttaacttaa gtggttataa tatagaaatt ctaaaagata ctgatagtag tgtaattgaa
     6421 gaagggttaa gatatgtaaa taatgatgca tgttatccag ctataatagt tgtaggtcag
     6481 ctaataacag cattaaaatc tggcaaatat gatttaaata atacttctgt tactataact
     6541 cagactggtg gaggttgtag agctacaaat tatattggat tcttaagaaa ggctatatat
     6601 gatgctggat ttaaagatgt tcctgtcatt gcacttagtg taaatggaat agaagatagt
     6661 ggtataatgg ataatatatc actaaaatta atcaatagac tctttatgtc tgttgtttat
     6721 ggtgatttgc tgatgaaagt actatataga gtaagaccat atgaaaaagt tactggaagt
     6781 gcaaatgctc tatatgaaaa atgggttgat atatgcaaat cttctcttgt taaagcaaaa
     6841 atttctgtat ttactagaaa tataaaagat atagtaaaag aatttgataa tttagagata
     6901 ctagatatca aaaaaccaaa agtaggtttg gttggagaaa tattggtgaa attccatcca
     6961 attgcaaata ataatttagt agatatatta gagcgagaag gtgctgaagc agtcgtgcca
     7021 gaccttacaa atttcttctt aagttgtgcc tttaatacta tatacaaaca cactcattta
     7081 gaaggaagta gaaagagtag aatgatagga gaagcattta tatacataac tggaatatat
     7141 caaagagtat ataaaaaagc acttgataag agtgagagat tttatgctcc agccaatata
     7201 aaaaatgttg ctaaaagtac agaaccagta gtgtcattag gtaatcaaac tggagaaggt
     7261 tggcttttaa caggtgagat ggttgaatta ttaaatgaag gtgtagaaaa cattatttgt
     7321 atgcaacctt ttggatgttt acctaatcac ataattggta agggttctat aaaagaatta
     7381 aagaggttgt ataaaaatgc aaatataata cctattgatt atgacccttc tgcaagtgag
     7441 gtaaatcaac ttaacaggat aaaacttatg ctttctaagg cttttaaaaa tatataagat
     7501 ttatattttg atatgttaaa agttaatgaa tttaaaaata tactctatat taagtatcta
     7561 taaaaaagag ttatcctatt ttttagggta actctttatt agttaaaaaa ttatatgtat
     7621 actgatatta aaggggggaa gtaatatgag tttagtatat gatgtttata aatcaaaatt
     7681 aggaaatttg tacatattaa gtgaagatgg ttttatagtt agtgtataca taggagatga
     7741 aaaatttaat aatttaaaaa atgaatgtat taaaaaagga attgatataa agataagtaa
     7801 ggaagattta aaggaagcaa taagccagat agatgattac tttaatggaa aaagaaaagt
     7861 ctttaattta aatattcgta ttgaagggac tgaatttcaa aaatcagttt atagggaaat
     7921 gttaaaaata ccttatggag aaacattgtg ttattcagat atagcaagaa atataaacaa
     7981 tccaaaatca gtaagagcaa taggacaagc aagtaaaagt aataaaattc caataataat
     8041 accttgtcat agagtagttg gcaaaaaaaa tattggtgga tatatgggga atcattctga
     8101 tttgaaagag atactattaa atttagaaag acagagttaa cttagaaaga aatgttttta
     8161 ttgttaatat ttgatataat aatagtaaaa agaagtattt tttacaaaaa caatgaagaa
     8221 tttattttaa tttacaaaaa tgagggggaa ttttaatgtg tgataaagtt atagcatcaa
     8281 aatatcatga gaagggattt aattgtgcag aatcagttat aaaagcatat aatgaggaat
     8341 ttaatacaga tataccagtt tgtttaggaa gtggactggg ttcagggtgt ggggttgcta
     8401 gtttatgtgg tgcagtaaat gcatcaaata taataattgg atacgtaaaa ggcagaaacc
     8461 acgaagatga aagtactaaa gctaaagtat atgctaaaga tttaactaca acagtaagaa
     8521 aagagtatgg ttcagagtta tgtatagacc taaaaaaaga tttagttgct tgtagagaaa
     8581 taatggattt cgcatatgat agtctaaagg aaactttaaa aaaagaatta taagaaaata
     8641 agctatcaag tataaattat ttgatagctt atttttatag tcgatactaa ataaatcaaa
     8701 tatattttag aattattatt tgtaaataaa cagcaaataa ttttaggatt tttatttaat
     8761 atagttttta tttatat
//
LOCUS       DAMJYN010000123         8731 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.128, whole genome shotgun sequence.
ACCESSION   DAMJYN010000123 DAMJYN010000000
VERSION     DAMJYN010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8731)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8731)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8731
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.128"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            24..788
                     /locus_tag="PC466_003336"
     CDS             24..788
                     /locus_tag="PC466_003336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YoaP domain-containing protein"
                     /protein_id="HDF2770689.1"
                     /translation="MQIIDININNIDSRHICCSISEKKGENCVFSKKAWMKNNFDKGL
                     AFKRFDVRGKAFIEYIPAENAWCPITADNYIFINCFWISGKFKGQGYSNLLLQECVDD
                     AKSKGKYGLVVLSSSKKMPFLSDAKYLKYKGFCLADTSEPNYELLYFPFTDNAPIPCF
                     KNCVKKRKLNENGIVLYYSNQCPHTEKYAPILKKIANSRGIDVNLIKFETAKEAQNAP
                     APFTTYSLFFNGEFVTNEILSEKKIEKFLDTNIKKI"
     misc_binding    1011..1224
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            1478..2512
                     /locus_tag="PC466_003337"
     CDS             1478..2512
                     /locus_tag="PC466_003337"
                     /EC_number="1.2.1.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyl-gamma-glutamyl-phosphate reductase"
                     /protein_id="HDF2770690.1"
                     /translation="MNKIKVGIIGATGYVGAELIRLLMNHDKVEVTAIGSNSYVGKNI
                     VDIYPSIGYKNNMICIENEKVIDMCDVVFTALPHGVSEKFVIKAIKSKKKVIDLGADF
                     RIKDEEVYSKWYGVSFIDKILHKKAVYGLSEIYKEDIKDADIIANPGCYPTSISLPLM
                     PLLSSKLIKNNNIIIDSKSGLTGAGRELSISSHFTEVNENITAYKIGKHRHTPEIEQN
                     LSESCKEKVSVVFTPNLIPVNRGILSTIYCTKEDNISINDIHRKLTDYYEFKEFIEVL
                     PLDKVASLKNVRFSNKCVISLHENGDTLIICSAIDNMIKGAAGQAIQNMNIIFGIEEN
                     TGLKNIAPSF"
     gene            2554..3771
                     /gene="argJ"
                     /locus_tag="PC466_003338"
     CDS             2554..3771
                     /gene="argJ"
                     /locus_tag="PC466_003338"
                     /EC_number="2.3.1.1"
                     /EC_number="2.3.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate
                     N-acetyltransferase/amino-acid acetyltransferase ArgJ"
                     /protein_id="HDF2770691.1"
                     /translation="MEIIKGGVTVSEGFFASGIHCGLRKNKEKRDLALVYSDVLCDAA
                     AVVTQNKVKGNPVYVTQEHIKNGKAQAIIVNSANANTFNGKEGLINAYKMAKFTSDKL
                     NIKENDVLVASTGVIGKPLNINLIEENMDELVNNLSKQGHIGAREAIMTTDIIKKEIA
                     VAIMYGDKKITIGGMAKGSGMIHPNMATTLGFITTDANIDGVLLKEALKIAVDKSFNR
                     VSVDGDTSTNDMVMILANGKAKNDRINKKDEHYQVFLSALTYVCIELAKLVAKDGEGC
                     TKLIECYINGALSEEHAVKLAKTVISSSLVKTAVFGADANWGRILCALGYAGEEIDME
                     KVDIIFESMKGYIEVCKNGNGLDFNEEKAKKILEDDEISILVDLNMGNARGNAWGCDL
                     SYDYVRINGSYRN"
     gene            3786..4646
                     /gene="argB"
                     /locus_tag="PC466_003339"
     CDS             3786..4646
                     /gene="argB"
                     /locus_tag="PC466_003339"
                     /EC_number="2.7.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylglutamate kinase"
                     /protein_id="HDF2770692.1"
                     /translation="MINIEKANTLIEALPYIEKHQGKTIVVKYGGSAMKKDGLKESVM
                     EDLVLMSYVGINIVLVHGGGAEINKMLAKVDIESKFVNGLRYTDEETMEIVKMVLAGK
                     VNKDLVNKIHTKGGKAVGLCGMDNNMILCDPYKNYELGFVGEIKKVNVELIESCLKSG
                     YISVIATIGVGDDGETYNINGDTAASAIAKELNADKLILLTDVPGLLREPDEEKSLIT
                     EVILEDVDKLFEEGIITGGMIPKIEGCVDALNNGVNRVHILDGRVPHSIITELFTDSG
                     IGTLIRKENE"
     gene            4676..5863
                     /locus_tag="PC466_003340"
     CDS             4676..5863
                     /locus_tag="PC466_003340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate aminotransferase family protein"
                     /protein_id="HDF2770693.1"
                     /translation="MNNNNTISKWNEYFIDTYNQPNFVIDYGEGSCFFDTNGNKYIDF
                     TSGYGVSSLGYSNSNLKNALKEQVDKLLHTSNLYFNEPVLYSGEKIINSSGMAKVYFC
                     NSGTEANETAFKIARKYSSDKYGNGRGTIISLKDSFHGRTMMSLMATGMDKYHKYFYP
                     LPEGFKYIERNNIEDLKNNLDSTVCAIILEAIQGEGGVNVLEKDYVLEIVKICQEKDI
                     VVIFDEVQCGIGRTGKLFGYEYFDVKPDIVTVAKGLGAGIPVGGVLVNKKLSKVLGKG
                     DQGTTFGGNLLAMVAASVVLDEISKDGFYNEVLEKGNYIRKSIESFNNKVVLKTKGIG
                     LMIGIETNIESSIIEEKARKKGLLILTAGKNVLRFLPPLTISYKEIDEALEILKDILL
                     EIN"
     gene            5972..6994
                     /gene="argF"
                     /locus_tag="PC466_003341"
     CDS             5972..6994
                     /gene="argF"
                     /locus_tag="PC466_003341"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HDF2770694.1"
                     /translation="MNNISLKGKSFLTLKDFTKEEIRYLLTLSSYLKTKKKVGIKGDL
                     LQGKNIALLFEKTSTRTRCSFEVAAHDEGAYVTYLGPNDCHMGKKESVSDTAKVLGRF
                     YDGIEFRGFKQETVESLAKYSGVPVWNGLTDEYHPTQILADFLTVIENVDKDLNKVKF
                     VYVGDARNNMGNSLMIGCAKMGIHFVALAPKELWPNEELVKEMKEIAKKSKGDIMLTE
                     NIDDVKGADVIYTDVWVSMGEEEQYEARINQLKDYQVNMDMIKKTENENVIFLHCLPA
                     FHDLETKVAQKIYEKFGLSELEVTNEVFNSKYSKVFEEAENRMHTIKAVMVSTMTDVN
                     MNNNLI"
     gene            7121..7738
                     /locus_tag="PC466_003342"
     CDS             7121..7738
                     /locus_tag="PC466_003342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4878 domain-containing protein"
                     /protein_id="HDF2770695.1"
                     /translation="MKKIILALTTFLLAISLTACSSAKPEDTIDSFFNSAKKFDFEGM
                     NKVMENNDEKYKDILKELDTKDPNAQYVLDYLKQNASKITYTIKDSEVKGDKATIKVE
                     CKFIDSTPLLQEIVAEAFTKMIGMSFSGQDLTDEKTTEMLVSIMKEKQKSVKETYVTK
                     TVEFECSKKDNKWIISSVNDAVADVLLSNLVTAGQEFSNSMNTLE"
     gene            complement(7958..8656)
                     /locus_tag="PC466_003343"
     CDS             complement(7958..8656)
                     /locus_tag="PC466_003343"
                     /EC_number="5.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid racemase"
                     /protein_id="HDF2770696.1"
                     /translation="MNEKLIGILAGMGPRSTAPFVDLIIDECQSQYGAKYDDEFPKMM
                     IYSLPTPFYIDRPINHELMKETIIDGLQKLESTGVNFIAMPCNSAHIYFKELKESINI
                     PILNIVEETVKKLPTISQKVTLFSTSSTFESTIYQNGIIHNGHEFIFKDEWQIKLNNL
                     IQNIKMDKENPHNIDIWNKLIEDVKNESIENIVIACTDLNVVLEKSYPSINIVDSSKC
                     LAESVVNKYLKLVK"
BASE COUNT         3506 a          861 c         1572 g         2792 t
ORIGIN      
        1 tgtaattaga aaaggagata agtatgcaga ttatagatat aaatataaat aatattgaca
       61 gtagacatat atgctgttca atttctgaaa aaaaaggaga aaattgtgtt ttttctaaaa
      121 aagcttggat gaaaaataat tttgataaag gtctagcctt taaacgattt gatgtaagag
      181 gtaaagcttt tatagaatat attccagcag aaaatgcatg gtgtcctatt actgcggaca
      241 attatatatt tattaactgt ttttggatat ctggaaaatt taagggtcaa ggatattcta
      301 atctattgct acaagagtgt gttgatgatg caaaatcaaa aggtaaatat ggattagttg
      361 tgctttcgtc tagtaaaaaa atgccttttt tatctgatgc taaatatcta aaatataagg
      421 gcttttgttt agcagataca tcagaaccaa attatgagct attatatttt ccctttactg
      481 ataatgctcc tattccatgt tttaagaatt gtgtaaaaaa aagaaaatta aatgagaacg
      541 gtatagtttt atattacagt aatcagtgtc cacatacaga aaaatatgct cctattttga
      601 aaaaaattgc aaattctaga ggtattgatg taaatcttat aaaattcgaa acagcaaaag
      661 aagcacaaaa tgctcctgca ccatttacta catacagtct tttttttaat ggtgaatttg
      721 taaccaacga gatactttct gagaaaaaga ttgagaaatt tttagatacc aacattaaaa
      781 aaatttaact aaaaatagat gtaaatattg tattttgaga ttacattatt ttataatcca
      841 atatattttg gaaatttctt aagttgatga atgataatat aaagattata actcaattta
      901 gatacaaaat gctggaaatt aaccatatag aaaatatttc caaaaattta aaaattatat
      961 tgacaaagtt aaaaaaataa actatcatat aaaacaataa gaaaataaat tgaaatcctg
     1021 tgaaaaagag agtagcataa agctagttga tagagagctg ggaatggtgg aagcctagta
     1081 acgaatttta ttgtgaatag agctttggag gagattacca gaagtaatag tatggtaatt
     1141 ggtgaatctc gccttaagag attagagtgg gtaagattat cttatcaatt agagtggtaa
     1201 cgcgggtgta tattcgtctc ttggtctttg accaagaggc ttttttaatt ttaaatgtac
     1261 attttgtaga tactttttaa tttgagtttt aatgattatt gtaattttac caatgagagt
     1321 ggtaccgcgg aaaatcgcct cttagtattt ataatgctaa ggggtttttt gttttaatta
     1381 gaatatttta atctacatat tatcaaatga ttatcatata gtaaagtgga aagatagaat
     1441 tttaatacta tttgaatata aaaatggagg gaacaaaatg aataaaataa aagttggtat
     1501 tattggcgca actggatatg tcggggcaga gttgattaga ttattaatga atcatgataa
     1561 agtcgaagtg acagcaatag gttcaaattc gtatgttgga aaaaatatag ttgatatata
     1621 tccaagtata ggatataaaa ataacatgat atgtatagaa aatgaaaaag ttatagatat
     1681 gtgtgatgtt gtgtttacag cccttccaca tggagttagt gaaaagtttg taataaaagc
     1741 aattaaatcg aaaaagaaag ttatagattt aggtgctgac tttagaataa aagatgaaga
     1801 agtatatagt aaatggtatg gagtatcttt tatagataaa atcttacata aaaaagctgt
     1861 atatggatta agtgaaatat acaaagaaga tataaaagat gcagatataa ttgcaaatcc
     1921 tggatgttat ccaactagta tttctttacc attgatgcca ttactaagtt ctaaattgat
     1981 aaaaaataat aatataataa ttgattctaa atcaggtctt acaggtgctg gtagagaatt
     2041 atcgattagt agtcacttta cggaggttaa tgaaaatatc actgcatata aaatagggaa
     2101 acacagacat actccagaaa tagaacaaaa tttaagtgaa tcctgcaaag aaaaagtaag
     2161 tgtagttttt acaccaaact taataccagt aaatagggga atcttatcaa ctatatattg
     2221 tacaaaagaa gataatattt ctataaatga tatacataga aaattaactg attattatga
     2281 atttaaagaa tttatagaag ttctcccatt agataaggta gcttctttaa agaatgttag
     2341 gttctcaaat aaatgtgtca tatcattaca tgaaaatgga gatacattga taatctgttc
     2401 agctatagat aatatgatta agggagcagc aggtcaagct atacaaaaca tgaatataat
     2461 atttggtatt gaagaaaata caggtttaaa aaatattgca ccatcatttt agtaatgaaa
     2521 aaatactaaa ctcatataat taggaggata aatatggaga ttataaaggg tggagttaca
     2581 gtttcagaag gattttttgc ttcagggatt cactgtggct tgagaaaaaa taaagaaaaa
     2641 agagatttag ctttggttta ttcagatgtt ttatgtgatg cagcagcagt agtaactcaa
     2701 aataaagtaa agggcaatcc tgtttatgtt acacaggaac acattaaaaa tggaaaagca
     2761 caagctatca tagtaaatag tgctaatgct aataccttta atggaaaaga aggacttata
     2821 aatgcttata aaatggctaa attcactagt gataaattaa atattaaaga aaatgatgtt
     2881 ttggttgcat ctacaggtgt cataggaaag ccattaaata taaatttaat agaagaaaat
     2941 atggatgaat tagtgaataa tctaagtaaa caaggtcata ttggagcaag agaagctatt
     3001 atgacaactg atattataaa aaaagaaata gcagtagcaa taatgtatgg agataaaaaa
     3061 ataactattg gaggtatggc aaaaggttct ggcatgatac atcctaatat ggcaacaacg
     3121 ttaggattta taactacaga tgcaaatatt gatggagttt tgctaaaaga agctttgaaa
     3181 attgctgttg ataaaagttt taatagagtt agtgtagatg gagatacaag tactaatgat
     3241 atggtgatga ttctagcaaa tggaaaagca aaaaatgata gaataaacaa aaaagatgaa
     3301 cattatcaag tatttttgag tgcacttaca tatgtctgta tagaacttgc taaacttgtt
     3361 gcaaaagatg gagaaggatg tacaaaacta attgaatgtt atataaatgg agcattaagt
     3421 gaagaacatg cagtaaaatt agcaaaaaca gttatatctt cttcattagt aaagacagct
     3481 gtatttggag ctgacgcaaa ttggggtaga atactgtgtg ctttaggtta tgcaggtgaa
     3541 gaaatagata tggaaaaagt tgatattatt tttgagagta tgaaaggata tattgaagta
     3601 tgtaaaaatg gaaatggatt agattttaat gaggaaaaag caaaaaaaat ccttgaagat
     3661 gacgaaataa gtatattagt agatttaaat atgggcaatg ccagaggaaa tgcatgggga
     3721 tgtgatttaa gctatgatta tgtaagaata aatggaagtt atagaaatta ggaggatata
     3781 ctttaatgat taatatagaa aaagcaaata cacttataga agctttacca tatatagaaa
     3841 aacatcaggg aaagactatt gtagttaagt atggtggaag tgcaatgaaa aaagatggtc
     3901 taaaagaatc tgttatggaa gaccttgtat taatgagtta tgttggaatc aatatagttt
     3961 tagtacatgg tggaggggca gaaatcaata agatgctagc aaaagtggat atagaaagta
     4021 aatttgtaaa tggtcttaga tatacagatg aagagaccat ggaaattgta aaaatggtac
     4081 ttgctggaaa ggttaataaa gacctagtaa ataaaataca tacaaaaggt ggaaaagcag
     4141 tagggctttg tggaatggat aataatatga ttttatgtga cccatataaa aattatgaac
     4201 ttggatttgt aggagaaatc aaaaaagtaa atgttgagct tatagaatct tgtctaaagt
     4261 caggttatat ttcagtaatt gcaactatag gtgttggaga tgatggagag acttataata
     4321 taaatggtga cacagcagct tctgctatag ctaaagagtt aaatgcagat aaattgatac
     4381 ttcttacaga tgtccctggt ttgttaagag agccagatga agaaaaatca ttaataacag
     4441 aagttatatt agaggatgtt gataaattat ttgaagaagg tataattact ggaggtatga
     4501 tacctaaaat agagggatgc gtagatgcct taaataacgg agtaaatagg gtacatattt
     4561 tggatggaag agttccacat tctataataa cagagctatt tactgatagt ggaataggta
     4621 cattaataag aaaagaaaat gaataaaatt ataagtttaa gaggggagaa taagaatgaa
     4681 taacaacaat acaatttcaa aatggaatga atattttata gatacatata accaacccaa
     4741 ttttgtcata gattatggtg aaggaagttg tttttttgat actaatggca ataaatacat
     4801 agattttaca agtggatatg gagtatcttc tcttgggtat agtaatagta atttaaagaa
     4861 tgctctaaaa gagcaagtag ataaattatt acatacttca aatttatatt ttaatgagcc
     4921 agtgttgtat tcaggagaga aaataattaa ttcaagtgga atggctaaag tatatttttg
     4981 taattctgga acagaagcaa atgaaacagc attcaaaata gcaagaaagt atagtagtga
     5041 caaatatggt aatggtagag gaactatcat aagtttaaaa gactcttttc atggtagaac
     5101 aatgatgtct ttaatggcaa ctggtatgga caaataccat aagtattttt atcctcttcc
     5161 cgaaggtttt aaatatatag aaagaaataa tattgaagat ttaaaaaata atcttgattc
     5221 cacagtttgt gcaataattc ttgaagcgat tcaaggcgaa ggtggagtta atgttcttga
     5281 aaaagattat gttttggaaa tagtaaaaat atgtcaagaa aaggatattg tagtgatttt
     5341 tgatgaagtc caatgcggta taggaagaac tggtaaactt tttggctatg aatattttga
     5401 tgtaaaacca gatatagtta ccgtagcaaa agggttggga gcaggaatac cagtaggagg
     5461 agtattggta aataaaaaac tttcaaaagt actaggaaaa ggagaccaag gtacaacttt
     5521 tggaggtaat ttattagcta tggtggcagc ttcagttgta ttagatgaga tatctaaaga
     5581 tggtttttat aatgaagtat tagaaaaagg aaattatata agaaaatcta ttgaaagttt
     5641 taataataaa gttgtattaa agacaaaagg tattggtcta atgataggaa ttgaaactaa
     5701 tattgaatct agtattatag aagagaaagc tagaaaaaaa ggattgctta ttttgactgc
     5761 tggaaaaaat gtattgagat ttttaccacc attaacaatc agttataagg aaatagatga
     5821 ggctcttgaa atcctaaaag atatattact agagattaac taaatattca aaaaatagtt
     5881 aattaaagat aaaaattaga agtaaataaa aaagtaaagt gctaacaagt ttaattgaat
     5941 ttaagaagtt tataagaagg ggcgaattaa tatgaataat ataagtttaa aaggtaagag
     6001 ttttttgaca ttaaaggatt ttacaaaaga agagattaga tatttattaa ctttatcaag
     6061 ttatttaaaa actaagaaaa aagttggcat aaaaggcgat ttgctacaag gaaaaaatat
     6121 agctttatta tttgagaaaa catcaacaag aactagatgt tcatttgaag tagcagctca
     6181 tgatgaagga gcatatgtaa cttatctagg tccaaatgat tgtcatatgg gtaaaaaaga
     6241 gtctgtatca gatacagcaa aagttctagg aagattctat gatggaatag aatttagagg
     6301 ctttaaacaa gaaacagttg aaagtctagc aaaatattct ggtgtacctg tttggaatgg
     6361 acttacagat gaatatcatc caacacaaat actggcagat tttttaacag taattgaaaa
     6421 tgtagataaa gatttgaata aagttaaatt tgtatatgtt ggtgatgcta gaaataatat
     6481 gggaaactca ctgatgatag gatgtgctaa aatgggaata catttcgtag cactagcacc
     6541 taaggaactt tggccaaatg aagaattggt taaggaaatg aaggaaatag ccaagaaatc
     6601 caaaggagat ataatgttga ctgaaaatat tgatgatgtt aaaggtgcag atgttatata
     6661 tacagatgta tgggtttcta tgggagaaga ggagcaatat gaagcaagaa taaatcaact
     6721 taaagattat caagtaaata tggatatgat aaagaaaact gaaaatgaaa atgttatatt
     6781 tttacactgt cttccagcat ttcatgattt agaaactaag gttgctcaga agatttatga
     6841 aaagttcgga ttatcagaat tagaggttac aaacgaggta tttaattcaa aatattcaaa
     6901 ggtatttgaa gaagctgaaa atagaatgca tacaataaaa gctgttatgg tttctactat
     6961 gactgatgta aatatgaaca ataatttaat atagatatgt tttaatatag actttacttt
     7021 aatgaaaatt tataaaatat tttaaatata ttattcaaaa actctcatta tatgttaaaa
     7081 taacttatgt atcaacaaat taagagggag gatttgagat atgaaaaaaa tcatattagc
     7141 tttaacaact tttttattag caatatcttt aacagcatgt tcaagtgcaa aaccagaaga
     7201 tacaattgat agttttttta acagtgcgaa aaagtttgac tttgaaggca tgaataaggt
     7261 aatggaaaat aatgacgaaa aatataagga tatattaaag gaattagata caaaagaccc
     7321 aaatgcccaa tatgttttag attatctaaa acagaatgca tctaaaatca cgtatacaat
     7381 aaaagacagc gaggttaaag gtgataaggc tacaatcaaa gtagaatgta aatttataga
     7441 ttcaacacca ttacttcaag aaatagtagc tgaggcattt acaaagatga ttggtatgag
     7501 tttttcagga caagacttaa ctgatgagaa aacaactgaa atgttagtat caattatgaa
     7561 agaaaaacaa aaaagcgtta aagagactta tgttacaaaa actgtagagt ttgaatgttc
     7621 taaaaaggat aataaatgga taataagttc agtaaatgat gcagtagctg atgtattgtt
     7681 atctaatctt gttacagcag gacaagaatt ttctaactct atgaatacac ttgaataata
     7741 ttgtttaggt gtagtaaagt aataaatata tgattatttt tataaataaa catataaata
     7801 tttatgaagg ataccatttt tggtatcctt tttattaata taatgaaata catggttaat
     7861 ttctatattg tcaagaaact atgatatatg ttataagtct atactattta aaataaactt
     7921 ataacatata ttttttataa tatagtgcat gaaaaattta tttaactaat tttagatatt
     7981 tattgacaac tgattcagcc aagcattttg atgaatcaac aatatttatt gaaggatatg
     8041 atttttctaa aactacattt aaatcagtac aagcaattac tatattttct atagattcat
     8101 ttttaacatc ttcgataagt ttattccaaa tatcaatatt gtgtggattt tctttatcca
     8161 tttttatatt ttgaataaga ttgtttaatt ttatttgcca ttcatcttta aatataaatt
     8221 catgtccatt atgtattata ccattctggt aaattgtaga ctcaaaagtt gaactagtcg
     8281 aaaaaagagt tactttttgt gagatagtag gtaatttttt aactgtttct tctacaatat
     8341 ttaatattgg tatattaata gactctttta attctttaaa gtatatatgt gctgaattgc
     8401 atggcattgc aataaaattt acaccagttg attcaagctt ttgtaatcca tcaattatag
     8461 tttctttcat aagttcatga tttattggac ggtcaatata aaatggggta ggtaatgaat
     8521 atatcatcat ctttggaaat tcatcatcat attttgctcc atattgagat tgacactcat
     8581 caataattaa atcaacaaaa ggggctgttg accttggacc cattccagcc aaaataccaa
     8641 ttaatttttc attcataaaa attatctcct ttatatataa atatatttat gtataaaata
     8701 aaaatctata aaagcataaa attatatttt a
//
LOCUS       DAMJYN010000124         8667 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.129, whole genome shotgun sequence.
ACCESSION   DAMJYN010000124 DAMJYN010000000
VERSION     DAMJYN010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8667)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8667)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8667
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.129"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(119..451)
                     /locus_tag="PC466_003344"
     CDS             complement(119..451)
                     /locus_tag="PC466_003344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HDF2770697.1"
                     /translation="MNTREMKEYRGFYNKKLSETDEFFRVFGSLDDKTYSEGAISKKN
                     KELMGLAISILSRCDECICYHIEGCINSGASKDEIIEAIKIGVIGGGSITYPNARFAI
                     KILEEFNI"
     gene            complement(695..1336)
                     /locus_tag="PC466_003345"
     CDS             complement(695..1336)
                     /locus_tag="PC466_003345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HDF2770698.1"
                     /translation="MKKAINKQFILSTLICFIPFIVSIYFYNRLPNEVAIHFDNYGNP
                     DNYAPKVIAAFGVPLLMLCIHLYTWFRLENEPKKANFSNVIQNLSKWGVAILSVILQI
                     LMVLYSTGVSLESNFYTGLILGIIVILFGNYLPKCKQNYSVGIILPWTLDDEDNWNKT
                     HHLAGWIWLIGGILLIINAFINIPFYNIFVIFVIVILPFIYSYLMYKISGKNN"
     gene            complement(1317..1610)
                     /locus_tag="PC466_003346"
     CDS             complement(1317..1610)
                     /locus_tag="PC466_003346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HDF2770699.1"
                     /translation="MGFPETFKALSDPIRREILVMLRENKMSAGEISEKFNMTNATIS
                     YHLSQLKKAGLIFETKYKNFIFYEINISVFEEVMLWFSQFMEKGEKDNEKSDK"
     gene            2004..2063
                     /locus_tag="PC466_003347"
     CDS             2004..2063
                     /locus_tag="PC466_003347"
                     /inference="COORDINATES: protein motif:HMM:NF024729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770700.1"
                     /translation="MIEYIYYYNNKRIKKINLA"
     gene            complement(2579..3247)
                     /locus_tag="PC466_003348"
     CDS             complement(2579..3247)
                     /locus_tag="PC466_003348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TSUP family transporter"
                     /protein_id="HDF2770701.1"
                     /translation="MPVLMAIGVPVHLAIGTNKFAASAGCISSAYRYAKSGKINNDLL
                     KKLVPFTIIGSVLGVRCVLSISEEILNVLVVVMILIVAIYTFISKNLGQEDNFEAVNK
                     KNLRLGMLMALIMGFYDGFFGPGTGTFLTFGFIKIYGYDFLHASANTKILNLTSNITS
                     LLLFMINGQVDYKIAIVFALVMIMGAYVGAKVAIKKGSKMIKPIFLVMALFMVVKLVY
                     QTLV"
     gene            complement(3192..3332)
                     /locus_tag="PC466_003349"
     CDS             complement(3192..3332)
                     /locus_tag="PC466_003349"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770702.1"
                     /translation="MFSVIFLCIGGFLAAFVDSIAGGGGTYKHACSYGNWSASTSCHW
                     YK"
     gene            complement(3391..5046)
                     /locus_tag="PC466_003350"
     CDS             complement(3391..5046)
                     /locus_tag="PC466_003350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2770703.1"
                     /translation="MVDFIESNNEVQKFDWGEVMWIHEPSKTQFNRLSAGIVRFFPGN
                     CQEKHFHLSEEQLLYVIQGEGIQMIDGKKVNIKETSIVYCPPYSEHEIINTGKIDLVI
                     LITYVPHKFSSLRQIPIVFSENNIQELVNVNIIENLANQISNILKLRISVYDLKYKGI
                     FETKKENKFCDICKNIKPCTKKLVKSINNDNFEKVYHCEYGVSSLEIPIVLEENIVGY
                     IECGNFIVYKSIDIDKNLSELSSSSGIDIKYINKIYNEFPLNPKSRLYVLKENLLMMS
                     EFIQEIAKRNFFENQLSIKDEEILKSRKENIRLEEALKKANSRLLEEEYIINPIDMFN
                     NSSKEYPFELELYIEKEIKNMNLEGVYNLIDTNKLRYNDVRDTIQEMIFVLSRTVLRD
                     LEDLKLISYLRNKYNKKISLVDSDEDLWNVLFEFSKECIDKNRAFWRKDKGNLIENIN
                     EYIKKYYKENINLNSISDVFFISPNYLSSIFNERNKVSITEYINLLRIEESKKYLLDR
                     SMSISDICKKVGFNNSSYFSQIFKKFNSITPNEYRKNMLDNKY"
     gene            complement(5275..5643)
                     /locus_tag="PC466_003351"
     CDS             complement(5275..5643)
                     /locus_tag="PC466_003351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF2770704.1"
                     /translation="MKYSITDVSKITKISSSAIRFYEEKGLLLPINRKPSGVRYFSEE
                     DVERLIFIKELKNTGLSIKDIHECFHFCDMGDGTIDKRIQLFQQHKQNIKNKIHELES
                     CMDKIDEKIYYLKEKKMCKK"
     gene            5792..6586
                     /locus_tag="PC466_003352"
     CDS             5792..6586
                     /locus_tag="PC466_003352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase"
                     /protein_id="HDF2770705.1"
                     /translation="MEKYATMIKEKLNEGKVLCGVAVSLSDSVVSELIGISGYDFIWI
                     EGEHSALDRKDIQQHMIAAHAGGAASLVRLVNSDPDLVKPIMDMGTDIICFPFINTVE
                     DAQKAVAACTYPPNGIRGYNPQRASYYGNMNYFDYVKNANNETLKMMLIEQKAGYDNL
                     EEIVKVEGIDIIALGPGDLSLDMGFSGYMNRIEIKDMISHAAEICKKYKMPFIIFPTI
                     EKKSIEEWVNIGANMLCFAQDTTFITYVINQLLSFYNEIVPIQKQH"
     gene            complement(6739..7167)
                     /locus_tag="PC466_003353"
     CDS             complement(6739..7167)
                     /locus_tag="PC466_003353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HDF2770706.1"
                     /translation="MSKIYIVYWSGTGNTEKMANFVAEGVKLKGKTPEVLDVSLLKPS
                     DLKEEDKFALGCPSMGAEQLEEGYMEPFVSELESMVSGKQIGLFGSYGWGNCEWMRDW
                     EERMQNAGATIIGGEGITAMEDPNEEAKDECIELGKTLAE"
     gene            complement(7643..8581)
                     /locus_tag="PC466_003354"
     CDS             complement(7643..8581)
                     /locus_tag="PC466_003354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family peptidase"
                     /protein_id="HDF2770707.1"
                     /translation="MNKRMKLIPYEINENLRGAKNKFPYGIKQMNARGMWDEGYTGKN
                     IVVGIIDTGCDISHPLLKGKIIGGANFSDDSNGNKNIYEDFNGHGTHVAGIIAASNYN
                     NEVMGVAPDCKLLIAKALNKDGTGTYQSIINAINFAVNNKVDIISMSLGGNKDDKNLK
                     NAVMQAVKNNISVVCAAGNNGDGDSSTSEYSYPASYAEVIEVGAINENYLVEKFSNSN
                     TTIDLVAPGRNIISTYMDNKLAIMSGTSMSAPYVSGSLALIKEWAREEFERDLDEAEL
                     YAQLIKCTRALGIPRTEQGNGYLYLNLYKYKNNSKR"
BASE COUNT         3008 a         1414 c          839 g         3406 t
ORIGIN      
        1 tatatttata tatgcaattc taaaaactta ataagaagtg aacttagaaa ataaagctta
       61 atttcaaaga cttaaataga atattattat tagtctaaat aaactacgtg tatcaaaatt
      121 atatattaaa ttcttctaaa atttttattg caaatcttgc gtttggatat gtaatagacc
      181 cgccaccaat tacacctatt tttatagctt ctataatttc atctttactt gctccagaat
      241 taatacaacc ctcaatatga taacaaatac actcatcaca tcggcttaaa attgaaatag
      301 ctagtcccat taattcctta ttttttttac ttatagcccc ttctgaataa gtcttatcat
      361 caagacttcc aaatactcta aaaaactcat ctgtttcact taatttttta ttgtaaaatc
      421 ccctatattc tttcatttct ctagtattca tcttctacct cctatgtttt tcttataaga
      481 gtatcacact gtacttatat tttcaatatt aaatacaaat tttcatttta tgttcattag
      541 cctaatttat attatttttt gaaatctcaa taagttatca tataagtaag attttttcag
      601 aactaaaata gaaatcttag taatttcttt attatctatc tcagttctga aatatattat
      661 tcttatccaa acattattat agtgattaat tatattagtt atttttacct gaaattttat
      721 acatcaaata agaatatata aatggtagta ttacaattac aaagattaca aagatattat
      781 aaaaaggaat attaataaat gcattaataa ttaataatat tccaccaata agccaaatcc
      841 atccagctaa atggtgtgtc ttattccaat tatcttcatc atcaagagtc catggcaaaa
      901 ttattcctac tgagtaattt tgtttacatt taggaagata gtttccaaat aaaataacta
      961 ttattcctaa aattaatcct gtataaaaat tagactccaa actaactcct gttgaatata
     1021 aaaccatcag tatttgtaga attactgaaa gtatagcaac tccccatttt gataaatttt
     1081 gtataacatt tgaaaaatta gcttttttag gctcattctc aagtctaaac catgtataca
     1141 aatggataca tagcattaac aatggtacac caaaagctgc tataaccttt ggagcataat
     1201 tatctggatt tccataatta tcaaaatgaa ttgcaacttc atttggtaat ctattataaa
     1261 aatatattga tacaataaat ggtataaaac atattaaagt agataaaata aattgtttat
     1321 ttatcgcttt tttcattatc tttttctccc ttctccataa attgtgaaaa ccaaagcata
     1381 acctcttcga aaactgaaat atttatttcg tagaaaataa agttcttata ctttgtttca
     1441 aatatgagtc ctgccttttt tagttgagat agatgataag aaattgtagc attcgtcata
     1501 ttaaattttt cactaatttc tcctgctgac attttattct ccctcaacat aaccaatatt
     1561 tctcttctta tagggtctga aagagctttg aatgtttctg gaaaccccaa caccatcacc
     1621 tcgctattta gaatttcatc taaatagaat ataacataac atccatttta tttcaataac
     1681 tatttagaaa aatttctaaa tagttatttc caaatattta ttgaaaattt tcatattaag
     1741 attctcaatt tacttaagtc gcttttatat aatcttattt tatctaattt ttttaattta
     1801 acaaaagtgt attgcaccac aattgttaaa gcaaaaacct aatgactgat atacttatat
     1861 atattacata tacttttaat ttcaaattaa aagtagctaa atccaattta aaaagtagtt
     1921 aagtcctatt taaatagaaa agaatgaaat aagaaatata ctgtataaaa atgcataaaa
     1981 acctctacta attagataca actataatag aatatattta ttattataat aacaaaagaa
     2041 ttaaaaaaat taatttagca taaccttgtt aaatatagat ttgaatatga atttaaagtt
     2101 atgtaaaatt aaaaatacag gaatgaaaat tccattcctg tataaaatct aacttttgag
     2161 tctcaataca atcttatttt gagacaatct tttttgtttt atattttctt atatttaaaa
     2221 tataacgcat atcttatgca acatattcat atttttcttt atattctttc atcgcatcat
     2281 tccaagcgtc ttgtactgtt acacctcttt tattagcaat tttttgtgcc agttcaatta
     2341 tcttcatagc tcttcttgat atgttcataa acattcctcc tacaaattac catatatttc
     2401 atatatataa atcaaggtta tatttttatg atatataatc cttctattgt aatattacaa
     2461 tttatatgtg tattatatat gaactatatt agaagataat tagaattttt ataaagctat
     2521 atgattagat taaatataaa agctttacaa ttacttataa atttaaaaag tctataaact
     2581 aaactaatgt ttgatatacc aattttacga ccataaataa tgccattact aaaaatattg
     2641 gttttatcat ctttgaacct ttctttatag caactttagc acctacataa gctcccatta
     2701 tcatcactaa tgcaaacact atagcaattt tataatctac ttgaccattt atcatgaata
     2761 ataacaatga agttatatta cttgttaagt ttaatatttt tgtatttgca gaagcatgta
     2821 aaaaatcata tccatatatt tttataaatc caaaagtcaa aaaagttcct gtacctggac
     2881 caaaaaaacc atcataaaaa cccattataa gagccataag catccctagt cttaaatttt
     2941 tcttattaac agcttcaaaa ttatcttctt gacctaaatt tttagaaata aaggtgtaaa
     3001 tagccactat taaaatcata accacaacca aaacatttaa tatctcttca cttattgata
     3061 atacacatct cacacctaga acactaccaa taatagtaaa tggtactaat ttttttaaaa
     3121 gatcgttatt aatttttcca gactttgcat atctataggc actacttata catcctgctg
     3181 atgctgcaaa tttatttgta ccaatggcaa gatgtactgg cactccaatt gccataagaa
     3241 caggcatgct tataagtccc tcctcctcct gctatagaat ctacaaaagc agctaaaaac
     3301 ccccctatac ataaaaaaat aactgaaaac ataaaattcc tccatcattc tctttcaatt
     3361 tttcttacaa tatatattat ataatcttat ttaatactta ttatccagca tattctttct
     3421 atattcattt ggagttatac tattaaactt cttaaatatt tgtgaaaaat aactactgtt
     3481 attaaaacct actttcttac aaatatcact aatactcatg cttctatcta acagatattt
     3541 tttagattct tctatcctaa gaagatttat atactcagtt attgaaactt tatttctttc
     3601 attaaaaata gaactcaaat aatttggact tataaaaaaa acatctgata tactattcaa
     3661 atttatattt tctttataat atttttttat atattcgttt atattttcaa ttagatttcc
     3721 tttatctttt ctccaaaatg ctctattctt atcaatacac tctttggaaa attcaaataa
     3781 tacattccat aaatcttcat cactgtctac aagtgatatt tttttattat atttatttct
     3841 taaataagat ataagtttta aatcctctaa atctctaagc actgttctag acaatacaaa
     3901 tatcatttcc tgaatagtat ctctaacatc attatatctt aatttgtttg tatctattag
     3961 attataaaca ccttctaaat tcatattttt aatttctttt tcaatataaa gttctaattc
     4021 aaagggatat tcttttgaag aattattgaa catatctatc ggattaataa tatactcttc
     4081 ttctaataat ctactatttg cttttttaag tgcctcttca agtcttatat tttcttttct
     4141 actctttaat atctcctcat cttttatact aagttgattt tcaaaaaaat tcctcttagc
     4201 tatttcctga ataaattcag acatcattaa taaattttct tttaatacat ataatctact
     4261 tttaggattt aatggaaatt cattgtaaat tttgtttatg tattttatat caataccaga
     4321 actacttgat aattcagata aatttttatc tatatcaata gacttatata ctataaaatt
     4381 accacattct atatatccaa ctatattttc ttctaatact ataggtatct ctaaactgga
     4441 aacaccatac tcacaatggt acactttttc aaagttatca ttatttatgc ttttaacaag
     4501 ttttttagta cacggtttta tatttttaca aatatcgcaa aatttatttt ctttcttagt
     4561 ctcaaatatt cctttatact ttaagtcata tacagatatt ctaagcttca atatattaga
     4621 tatttgattt gcaagatttt caattatgtt tacattaact aactcttgta tattgttttc
     4681 agaaaatact ataggtattt gtctcaaact cgaaaattta tgaggaacat aagtaattaa
     4741 tattactaaa tcaattttac cagtgtttat aatttcatgt tctgaatatg gtgggcaata
     4801 aactatagat gtttccttta tattgacctt tttaccatca atcatttgta ttccttctcc
     4861 ctgaatcaca tataaaagct gttcttcact taaatgaaaa tgcttttctt ggcagtttcc
     4921 cggaaaaaat cttacaattc cagcactaag tctattgaat tgtgtttttg atggttcgtg
     4981 tatccacata acctctcccc aatcaaattt ttgtacttca ttatttgact caataaaatc
     5041 caccataaac tcacctcgta gtttttatct aaatattttt ttattccttt aaatatctcc
     5101 ttataatata cattatcata attttctttt ttattgtata gataaatagt tatatagaac
     5161 attgtccaat tcttcctaaa aatatagtgt aaaaaatctt tcctcaaatg tttccaattg
     5221 aatttactct ttatattaga aaaatcaaaa aattatttct ttattctata aggattattt
     5281 tttacacatc tttttttctt ttaagtaata tattttctca tctattttat ccatacaact
     5341 ttctagttca tgtattttat ttttaatgtt ttgcttatgt tgttgaaata attggattct
     5401 tttatctatt gtaccatctc ccatatcaca aaaatgaaag cattcatgga tatctttaat
     5461 agataaacca gtatttttta attctttgat aaatattaga cgctctacat cttcttcaga
     5521 gaaatagcga acaccacttg gttttctatt gataggaagt aataaacctt tttcttcata
     5581 aaatcgaata gcagatgaag aaatttttgt tatttttgat acatcagtta tagaatattt
     5641 cataatctct acctccctaa attttatatg aataagaata ttataaaaat accttataca
     5701 gtagtcaaca aaaaagtatt gacttcaagt taggttgaag ttgtactctt tgaagtgtaa
     5761 aagaaaactt acaaaagaaa ggatgatata aatggaaaaa tatgcaacta tgattaaaga
     5821 aaagctaaat gaaggaaagg tcttatgtgg agtagctgtt tcactgtctg attcagttgt
     5881 aagtgagtta atcggtatat ctggatatga ttttatttgg attgaaggag aacatagtgc
     5941 tttagaccgt aaagacattc agcaacatat gatagctgcc catgctggtg gtgctgcttc
     6001 tttggtacga ttagtaaaca gtgaccctga ccttgttaag cccataatgg atatgggaac
     6061 agatattatt tgtttcccat ttattaatac agtagaagat gcacaaaaag ccgtagcagc
     6121 ttgtacttat cctccaaacg gtataagagg atataatcct caaagagcct cttattatgg
     6181 gaatatgaat tattttgact atgtcaaaaa cgcaaacaat gaaacattaa aaatgatgtt
     6241 aattgaacag aaagcaggtt atgataatct tgaagaaata gtaaaagtcg agggtattga
     6301 tattatagca ttaggccctg gtgacttatc tttagacatg ggtttttccg gatatatgaa
     6361 tagaattgaa ataaaagata tgatttctca tgctgctgaa atatgcaaaa aatataagat
     6421 gccctttatt atttttccta caatagaaaa gaaaagtatt gaagaatggg ttaatattgg
     6481 agcaaatatg ctttgttttg cacaagatac tacctttatc acttatgtta tcaatcaatt
     6541 attatctttt tataatgaga ttgtaccaat tcaaaaacaa cattaaatta taaatctaat
     6601 tttatattaa aagagactaa tattttatct atctctatta aggatatttt cttatgtatc
     6661 ataatattag tctctcttat tattatatac tgctatcatc attagttgct atttatacta
     6721 tttttataat atacaaattt attcagctaa cgttttgcct aattctatac actcatcttt
     6781 tgcttcttca tttgggtctt ccattgctgt aattccttct ccaccaataa ttgtagcacc
     6841 agcattttgc atacgttctt cccagtctct catccattca caatttcccc atccatatga
     6901 accaaataat ccaatctgtt tacctgatac catagattct aattctgaaa caaatggctc
     6961 catatacccc tcttctagtt gctctgctcc catagatggg caacctaatg caaatttatc
     7021 ttcttctttt aaatcacttg gtttcagtaa gctcacatct aaaacttctg gtgtcttacc
     7081 ttttaacttc acaccttcag ccacaaaatt tgccattttt tcagtatttc ctgttccact
     7141 ccaataaaca atatatattt tactcatttt tacctcctgt agtatttttt aattaatcaa
     7201 tagttagtta tagctaacta acatctaaaa aacaaaagat ttctttatct gaaatctctt
     7261 tatttttcta aatatagaat atcacaattg attttgaaat tcaatattta ttgataatat
     7321 ttatcattta tattttatat tcattttata atatcaaaac actgtatcgt atttctaatc
     7381 tttcatagaa aaatttctaa cttatagtac ttttgcatct cttataaatc ttttatatgt
     7441 ataagtacat agaaaaacac accttttcca gatgtgctat ctataatatc gtatatttat
     7501 ttttcaattc taactagcta atatgtttat aaattttatc acttaatacc tttatacatt
     7561 gatgtaaaat cttacaccta agtaattttt attatttgtc tcgactctat ataatatagc
     7621 tattttatca tcaaatcaaa aattatcttt tgctattatt cttgtattta taaagattta
     7681 aatataagta tccatttcct tgttccgttc taggtattcc aagcgctctc gtacatttta
     7741 ttaattgtgc atacagttca gcttcatcta aatctctttc aaactcctct cttgcccatt
     7801 ctttaattag tgctaatgag cctgatacgt atggtgcact catactagta ccactcataa
     7861 tagcaagttt attatccata taagtcgata taatatttct tcctggagcc accaaatcta
     7921 ttgtagtatt tgaattacta aacttttcaa ccaaatagtt ttcatttatt gcacctactt
     7981 ctattacctc agcataactg gctggataac tatactcact tgtactagaa tcaccatctc
     8041 cattattacc tgctgcacac actacagaaa tattattttt tactgcttgc atgacagcat
     8101 tttttaaatt cttatcatct ttgtttcccc caagagacat agatataata tcaaccttgt
     8161 tatttacagc aaagttaata gcattaatta tactttgata tgttccggta ccatctttat
     8221 ttaatgcttt tgctattaat aatttacaat ctggagctac tcccataact tcattattat
     8281 agttagatgc agctataata cccgccacat gagttccatg gccattaaaa tcctcatata
     8341 tatttttatt tccattactg tcatcactaa aatttgcacc accaattatt tttcctttta
     8401 aaagaggatg agatatatca caacctgtat ctattatacc aactacaata tttttaccag
     8461 tataaccttc atcccacatt cccctagcat tcatttgttt tattccatat gggaatttat
     8521 tttttgcacc tcttagattt tcatttattt catacggaat tagtttcatt cttttattca
     8581 tcatatatcc tcctaaaaat tttattgctt ataaaaatca tgaattttat tttataatag
     8641 gtttataaat caaattaaaa cctatat
//
LOCUS       DAMJYN010000125         8542 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.130, whole genome shotgun sequence.
ACCESSION   DAMJYN010000125 DAMJYN010000000
VERSION     DAMJYN010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8542)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8542)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8542
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.130"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(23..247)
                     /locus_tag="PC466_003355"
     CDS             complement(23..247)
                     /locus_tag="PC466_003355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HDF2770708.1"
                     /translation="MTVYNLKLGQKGIIDNIAGNEKLMKRLLALGLIDGTEVEVKKIA
                     PLNDPIVIRFRGFDLAIRKSDAKNINLKNN"
     gene            complement(344..1597)
                     /locus_tag="PC466_003356"
     CDS             complement(344..1597)
                     /locus_tag="PC466_003356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:glutamate symporter"
                     /protein_id="HDF2770709.1"
                     /translation="MITLSFDIVQTLTLSIFFFLIGNLLKNKVNFLNNFCIPAPVIGG
                     LLFCFLNLFFKYFNIADISISGNLMPNFITFFFTTIGLEISINLIKKGGSVLFRYWIL
                     CGVLAFCQNILAITISKIIKLEPLLGLMCGNVSMEGGHGYSAAFGLTIENLGIEGAVG
                     VGLSAATIGLIMGGILGCPVAKFLINKYKLKPSSNIGLSIPRYNRNLKRFGSKFFRNK
                     NRIKNNNFSETITPSVFLEQVLLIFICINTGEIISRCFYITFNILLPSVVTCMFSAVI
                     FRNLNDKINILELNFKLIDFLKELSLGIFLTLSLMNIDLFELSTLLPPILLIVTFQVI
                     FIILFSIFICFRVLGKDFDSAIIISGLIGHGIGATPNALANMSSLTQKYGDSPKAFLV
                     VPLVSGFLLDAISIPCILFFINILT"
     gene            1857..2846
                     /locus_tag="PC466_003357"
     CDS             1857..2846
                     /locus_tag="PC466_003357"
                     /EC_number="3.5.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HDF2770710.1"
                     /translation="MFENLPKIDLHCHLDGSVRVETMLDIAIKEKIDLPSNNMDEIKK
                     LAKVSFNCTSLDEYLEKFDLPLKVMQSKENLKRITFELLEDASRENVKYIEIRFAPLL
                     HTQKGMSVKNIIEGIIEGIREAESIYDIKGNLILGCMRTMTSKEALLVIEEGKSFVNK
                     GVVAVDLCGPEKEGFCKEYKDVFKLAREYGYKVTIHAGEAASGENVLDAINILKADRI
                     GHGVKIKDHKKAYNLVKDKKILLELCPTSNVQTKTVDSYEVHPFYTFYKDNLHVSINT
                     DNRTVSDINLSSELNVIFDTFKLGLEDYKIIYRNAVEASFADKETKEYLNSLI"
     gene            2918..3658
                     /locus_tag="PC466_003358"
     CDS             2918..3658
                     /locus_tag="PC466_003358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EcsC family protein"
                     /protein_id="HDF2770711.1"
                     /translation="MKDYEDVVYIKLVKKELEEWKKNILKKPSIFDKASKGIQNKFNG
                     VLPDKYHEIITSSIKVMTKTVLFGYKYATKPPLRNMSLEEREKLVLEKAKTYKTTAMI
                     EGAGTGAGGILLGLSDFPLLLGIKVKFLYDVASIYGYDVKDYRERIYILNILQLAFSS
                     QQHINKTFKLMNNWDEYVNSLPEDINDFDWRTFQQEYRDYLDLAKFLQLMPGIGAFVG
                     FYVNGKLIDKLCETAVSAYRLRIRELKL"
     gene            3858..5009
                     /locus_tag="PC466_003359"
     CDS             3858..5009
                     /locus_tag="PC466_003359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyacyl-CoA dehydratase"
                     /protein_id="HDF2770712.1"
                     /translation="MTNLPKQFDSFNEARQKGFINAKELKESGKKMVGVFCTFTPVEI
                     PMAAGATVVGVCGVSEEPIPDAERVLPRNLCPLIKSSYGHAITDTCPYFYFSDLLIGE
                     TTCDGKKKMYEELAKVKPTYVMHLPNTSKGEFAYKLWKDEMIRLKEEVEKSLGVTITE
                     EDIRTAIKDKNEERELLKEFYALGKLEPSALTGLELHNVLYQAGFKFDRAELKHSLRK
                     VIDDMKERYEKGECPVQKDKPRILITGSPIGGISEKIVKTLEDAGASVVAYELCGAIR
                     SNDLLVDEEIEDVYDALTQKYINIGCSCMMNNDNRIELLDRIIDEYNVDAVIDVVLQA
                     CHTFNIESYRIREFVTKEKNKPFMSLETDYSKSDTEQLRTRFEAFVEML"
     gene            5034..5789
                     /locus_tag="PC466_003360"
     CDS             5034..5789
                     /locus_tag="PC466_003360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyglutaryl-CoA dehydratase"
                     /protein_id="HDF2770713.1"
                     /translation="MFSIGVDSGSVATKGVLFDGEKIIKKIIIPTGWSPKNTSKQVYE
                     LLSSEIDKKDIKKVVGTGYGRGVMDFADKKVTEITCHTRGIYFLNKNIRTILDVGGQD
                     SKVINLDRDGNVFNFIMNDKCAAGTGRFLEITSNLLGSDIESIDTLAKGYEPVNISSM
                     CTVFAESEIVSLLAQNISTGEVAAGILKSIANKSTSMLARGEVIDEVAFTGGLAKSKE
                     LVKMIEEILGKKIFIAEDTQIIGALGAAVIGFR"
     gene            5981..8368
                     /locus_tag="PC466_003361"
     CDS             5981..8368
                     /locus_tag="PC466_003361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding cysteine protease Cwp13"
                     /protein_id="HDF2770714.1"
                     /translation="MKKFTSKKVARFVALFLISILVMSTIPVSADNSNTLNQIKKAEY
                     SDTYKQYLNDAKNGRTEKYNGIIPNPYQLEGTQIQSKGRTAPTSYDPRKLGLMTSVKN
                     QEDLGICWDFAAMATLESFLKLNNYGDYDLSEEHLRWWASDGEYGWSVNDMDGALNYE
                     AMGYLTSWSGPKLEKDIPYNGRVSKAQGAKKPTNMNTAPTVFNVTDAVCVSNDINSTK
                     NAILQYGAVTSGYYEDIKYQSDDQNSYYCPTKSFNTNHAISIVGWDDNYSKDNFNANI
                     RPSKNGAWLIKNSWGDYNSEGGYFWISYEDKTLMSDIDNFSIKGGKKPNDDEKMYQHD
                     YASIVPLISKKITAANVFDFNRGDETLKSVMFLTESIGAKYEVSYAPVVNGIPQENNM
                     KKLKEGTAQYSGYITVPIDSFNIPEGKGAIVVSIEGKNGESTIGSESNVPGYDTFKAK
                     ANLGESYIIDNTGKFFDINRDSNFYPCNFTIKAVTEKSSGESIPNESLIGSDRYETAI
                     KVSQNGFNSSENVVLVNGSSIVDALAATPFTSAINSPILLTQKEALNSKTKAEIQRLG
                     AKKVYLIGGENSISKEIEQQLKSLNISIERISGSDRYKTSLLLAQKLNGIKNVSQIAV
                     VNGVKGLADAISVGAAAAENNIPIILANEKSELQGADEFLNSLNIEKSYIIGGTASLS
                     NNLESKLKNPTRLSGSSRDETNSKIIDNFYKKDTLKNAFVVKNGIKNQNDLIDGLAVG
                     PLGAKTGSPVILVGDKLADSQKEVLKNKTLEKVTQVGGGANKNAFKELVKLKSAK"
BASE COUNT         3420 a          956 c         1460 g         2706 t
ORIGIN      
        1 taaaatctct ttttattata tattaattat tttttaaatt tatatttttt gcatcagatt
       61 ttctaatagc taagtcaaac cctctaaatc taatcactat agggtcatta agaggagcta
      121 tctttttcac ttcaacttca gtgccatcta ttagtcctaa ggctagaagt ctcttcataa
      181 gtttttcatt tccagctata ttgtctataa ttcccttttg tccaagtttt aagttgtaaa
      241 cagtcattat taacacctcc taatgaaaat cattatcaaa ctttatattt ataatatata
      301 acaaaaagag taaattgtca atatataaca aaaaataaac atactaagtt agtatgttta
      361 taaaaaatag tatacatggg atactaatag catctagcaa aaaaccactt actaatggta
      421 caaccaaaaa ggcttttgga gaatcaccat atttttgtgt caaagaactc atatttgcca
      481 aagcgttcgg agtagctcct attccatgtc caatcaaacc acttattatg atggcagaat
      541 caaaatcttt tccaagtact ctaaagcaaa taaatattga aaataggatt ataaagatta
      601 cttgaaaagt tactattaag agaataggag gtaataatgt agataattca aataaatcta
      661 tattcataag tgataaagtt aaaaaaattc ccaatgaaag ttcttttaaa aaatctataa
      721 gtttaaaatt taattctaat atatttatct tatcatttaa atttctaaaa ataacagctg
      781 aaaacataca agttacaaca gagggtaata gtatattaaa cgttatatag aagcatctac
      841 ttataatttc tcctgtattt atacaaataa atatgagaag aacctgttcc aaaaatacag
      901 atggtgttat tgtttcggag aagttattat tttttatcct attcttattt ctaaaaaatt
      961 tacttccaaa tctctttaga tttctattat atctaggaat cgacaagcct atatttgatg
     1021 atggttttaa tttatattta tttattagaa atttagctac aggacatccc aatataccac
     1081 ccataataag tcctattgtt gcagcagata atccaacccc aactgctcct tctataccga
     1141 gattttctat tgtaagtcca aatgcagcag aataaccatg accaccttcc atagatacat
     1201 ttccacacat aagccctaaa agaggttcaa gttttataat ctttgatatt gtaatagcta
     1261 atatattttg acaaaatgcc aatactccac acaaaatcca atatctaaat aatacactac
     1321 cacctttctt tataagattt atgcttattt caagtcctat agttgtaaaa aagaaggtta
     1381 taaaatttgg cattaaattt ccacttatag atatatctgc tatattaaaa tatttaaaaa
     1441 ataaatttag aaaacaaaat aatagacctc ctattactgg tgcaggtata cagaaattat
     1501 ttaaaaagtt aactttattc ttcaataaat taccaattaa aaagaagaat atagatagtg
     1561 tcaaggtttg cactatatca aaacttaagg taatcaaaat aagtcctcct ttgtaattca
     1621 aagttttaat tatataactt aaattcttat gtattgaaat tttattatca aatgtatatt
     1681 aataaatgta tattaaaaag aatcagtata tataattaga tagtcataaa ttaaattaaa
     1741 atattttaat gagatgtgac ttttttagaa tgaaaaaccg tagtatattg atataataga
     1801 aataagactt aaaaatctgt tgatagtatt atttataagt acagtaggag gataaaatgt
     1861 ttgaaaattt acctaagata gatttacatt gccacttaga tggaagtgtt agagtagaaa
     1921 ccatgcttga tatagctatt aaagagaaaa tagatttacc ttcaaataat atggatgaaa
     1981 taaaaaaatt agcaaaggtt tcttttaatt gtacttcact agatgaatat ttagaaaaat
     2041 ttgatttacc cttaaaagta atgcaatcta aggaaaattt aaaaagaatt acttttgaac
     2101 ttttggaaga tgcaagtaga gaaaatgtaa aatatattga aattagattt gcaccattac
     2161 ttcacaccca aaaaggtatg agtgttaaaa atataattga gggtataatt gaaggaatta
     2221 gagaagctga aagtatttat gatataaaag gcaatttaat attaggttgt atgagaacaa
     2281 tgacctcaaa agaggcatta ttagtaattg aagaagggaa atcatttgta aataaaggtg
     2341 ttgtagcagt agacttgtgt ggtccagaga aagagggatt ttgtaaggaa tataaagatg
     2401 tttttaaatt agcaagagaa tatggatata aagttacaat acatgcagga gaagctgcaa
     2461 gtggagaaaa tgtattggat gctataaata ttttaaaggc ggataggatt ggtcatgggg
     2521 taaaaattaa agaccataaa aaggcgtata atttagttaa agataaaaaa atattgcttg
     2581 aattatgtcc aactagtaat gtacaaacta agacagtaga ttcttatgag gtacatccat
     2641 tttatacttt ttataaagat aatttacatg taagtataaa tactgataat agaactgtat
     2701 cagatataaa tttaagttca gaactaaatg ttatatttga tacttttaaa ctaggattag
     2761 aagactataa aattatttat agaaatgcag tagaagctag ttttgcagat aaagaaacta
     2821 aagagtattt gaatagttta atttaataga taaaaatatt taaactttaa attaagctat
     2881 taaattgaca aaaatacatt gtattaggag aaaaaatgtg aaagattatg aagatgttgt
     2941 ttatattaaa ctagtcaaaa aagaacttga agaatggaag aaaaatatat taaagaaacc
     3001 ttctatattt gacaaagcat caaagggtat acagaataaa tttaatggag tattgccaga
     3061 taaatatcat gaaataatta cttcttctat aaaagtaatg acaaaaaccg tactgtttgg
     3121 atataaatat gctacaaagc caccacttag aaatatgtca ttagaagaaa gagaaaaatt
     3181 agttttagaa aaagctaaaa cttacaagac cacagcaatg attgaagggg caggaacagg
     3241 ggcaggagga atcctcttag gtttatctga ttttcctttg cttttaggta ttaaagtgaa
     3301 atttttatat gatgtagctt caatatatgg atatgatgtt aaagattata gagaaaggat
     3361 ttatatatta aacatattac agttggcttt ttctagtcaa cagcatataa acaaaacttt
     3421 taaattgatg aataactggg atgaatatgt aaatagtcta ccagaagaca tcaatgattt
     3481 tgattggaga acatttcaac aagagtatag agattattta gatttagcta agtttttaca
     3541 actaatgcct ggaataggag catttgtagg attttatgtg aatggaaaat taattgataa
     3601 attatgtgaa actgctgtgt ctgcttatag attgaggatt cgagagctta agttataaga
     3661 gaaattataa cataaaaaat tagttataca atatatctat atgtatctaa ttttgcattg
     3721 ataaaaacaa ttatggataa aaggtaaagc atgatagaat ctaatgtaga ggtttgtatt
     3781 ttaatggaaa aatttagttt ttattgctta agatacaaat tgaattacga agagaagtaa
     3841 ttgggaggaa tattttcatg acaaatttgc caaaacaatt tgatagcttc aatgaagcta
     3901 gacaaaaggg atttataaat gcaaaggaac ttaaggaaag tgggaaaaag atggttggag
     3961 ttttctgtac atttactcca gttgaaattc caatggcagc tggagcaact gtagtaggtg
     4021 tatgcggtgt tagtgaagag ccaatacctg atgcagaaag ggtgcttcca agaaatcttt
     4081 gtcctttaat taaatcaagc tatggacatg caataacaga cacctgtcct tatttctatt
     4141 tttctgattt gttgatagga gaaaccactt gtgatggtaa gaaaaaaatg tatgaagaac
     4201 ttgcaaaagt taagccaaca tatgtaatgc atttgccaaa tacttcaaaa ggagaatttg
     4261 cctataaact ttggaaagat gaaatgataa gattaaaaga agaggttgag aaatctttag
     4321 gtgtaactat aactgaagaa gatataagaa ctgctataaa agataaaaat gaagaaagag
     4381 aacttttaaa agagttttat gcacttggta aattagaacc atctgcactt acaggccttg
     4441 agttacataa tgttttatat caagcaggtt ttaaatttga ccgtgcagaa cttaaacatt
     4501 ctttaagaaa agttatagat gatatgaaag aaagatatga aaaaggtgaa tgtcctgttc
     4561 aaaaagataa gccaagaata ttgataacag gttctcctat tggtggaata agcgaaaaaa
     4621 tagttaaaac tttagaagat gcaggggcat cagtcgttgc atatgaactt tgtggagcta
     4681 ttagatcaaa cgatttattg gttgatgaag aaatagaaga tgtatatgat gctttaacac
     4741 aaaaatatat aaatataggt tgttcttgta tgatgaataa tgacaatcgt attgaattat
     4801 tagatagaat aatagatgaa tataatgtag atgctgtaat agatgtagtt ttacaagcat
     4861 gtcatacatt taatatagaa agttatagaa taagagaatt tgttacaaaa gaaaaaaata
     4921 agccatttat gtctcttgaa actgattatt caaaatcaga tactgaacaa ttaagaacta
     4981 gatttgaagc gtttgtagag atgttgtagg aataaataaa agtaggagga actatgttta
     5041 gtataggagt tgactcaggg tcagtggcaa caaagggtgt gctatttgat ggtgaaaaaa
     5101 ttattaagaa aataattata ccaactggat ggagccctaa aaatacatct aaacaggtct
     5161 atgagttgct aagtagtgaa attgacaaaa aagatataaa aaaggtggta ggtacaggtt
     5221 atggaagggg agtaatggat tttgctgata agaaagtaac agaaataact tgtcatacta
     5281 gaggtattta ctttttaaac aagaacataa ggactatttt agatgtaggt ggtcaagata
     5341 gtaaagttat aaatttagat agagatggaa atgtatttaa ctttataatg aatgataagt
     5401 gtgctgcagg aactggtcga tttttagaga ttacttctaa ccttttagga agcgatattg
     5461 aaagtataga tacattagct aaaggatatg aaccagttaa tatatctagt atgtgtacag
     5521 tttttgctga gtctgaaatt gtaagtcttc tagctcaaaa catttctact ggagaggtag
     5581 cagcagggat acttaaatct attgcaaata aatccacctc aatgttagca agaggtgagg
     5641 taatagatga agttgcattt actggagggc ttgcaaaaag taaagaacta gtaaaaatga
     5701 tagaagaaat actgggtaaa aaaattttta ttgcagaaga tactcaaata ataggagctt
     5761 taggagctgc tgtaatagga tttagataaa aacatataaa aagaaaatga aaagctgaat
     5821 ttatcataaa taagttcagt tttttatttt attttgttta tttataaagg aaaactttgg
     5881 tataattgat ttaaatgatt gtatatttgt aaatacttga tatttagtca tatataacat
     5941 tagaatttta aaaattagct caaaataagg gggagaaagc gtgaaaaaat ttacttcaaa
     6001 aaaagtagca aggtttgttg cactgttttt aatatctatt ttagtaatgt caacaattcc
     6061 tgtgtcagct gacaatagca atacattgaa tcagataaaa aaagcagaat acagtgatac
     6121 ttataaacaa tatctaaatg atgctaaaaa tggacgtaca gaaaaatata atggaattat
     6181 accaaatcca tatcagttag aaggtactca aattcaaagt aaaggaagaa cagctccaac
     6241 atcttatgac cctagaaaat taggtcttat gacatcagta aaaaatcaag aggatttagg
     6301 aatatgctgg gattttgctg caatggcaac cttggaaagt ttcttgaagt taaataatta
     6361 tggagactac gatttatcag aagaacactt aagatggtgg gcttcagatg gtgaatatgg
     6421 atggtctgta aatgatatgg atggtgcttt aaattatgaa gctatgggat atttaacatc
     6481 ttggtcaggt cctaaattag aaaaagatat cccatacaat ggtagagtat ctaaagcaca
     6541 aggagcaaaa aaaccaacta atatgaatac agcacctact gtttttaatg tgacagatgc
     6601 tgtgtgtgta agtaatgaca taaattctac aaaaaatgct atattacagt atggagcagt
     6661 aacatctggt tattatgaag atattaaata tcaaagtgat gaccaaaatt catattattg
     6721 tccaacaaaa agttttaata caaatcatgc tatttcaatt gtgggttggg atgataacta
     6781 ttctaaagat aattttaatg caaatattag accatcaaaa aatggtgctt ggttaataaa
     6841 aaatagctgg ggagattata attctgaggg tggatatttc tggatatctt atgaagacaa
     6901 gacacttatg tctgatatag ataatttttc aatcaaaggt ggtaaaaaac caaatgatga
     6961 tgagaagatg tatcaacatg actatgcaag tattgtacct ttaatttcaa aaaagataac
     7021 agctgcaaat gtatttgatt tcaatagagg cgatgaaact ctaaaatctg taatgttctt
     7081 aactgaaagt ataggagcta agtatgaagt atcttatgct ccagtagtaa atggtatacc
     7141 tcaagaaaac aatatgaaaa aattaaaaga aggtactgcc caatattcag gatacataac
     7201 agttccaatt gattctttta atataccaga aggaaagggt gcaattgtag tcagtataga
     7261 ggggaaaaat ggagagtcaa ctataggttc tgagtcaaat gtaccaggat atgatacatt
     7321 taaagcaaaa gctaatttag gtgaaagtta tatcatagat aatactggaa aattctttga
     7381 tataaataga gatagtaact tctatccgtg taattttact ataaaagctg ttacagaaaa
     7441 gtcttctggt gagagtatcc cgaatgagtc tttaattggt agtgatagat atgaaactgc
     7501 tatcaaagtt agtcaaaatg gtttcaattc ttcagaaaat gtagttttag taaatggcag
     7561 ttcaatagta gatgcattgg cagcaactcc ttttacatct gctataaatt caccaatatt
     7621 attgacacaa aaagaagctt taaattcaaa aactaaagct gagatacaga gattaggtgc
     7681 taagaaagta tacctaatag gcggagaaaa ttctataagt aaagaaattg aacaacaatt
     7741 aaaaagctta aatatatcga tagagagaat atcaggaagt gatagataca agacaagttt
     7801 attattagct caaaagttaa atggtataaa aaatgtatct caaatagcag ttgtaaatgg
     7861 agtgaaagga ttagctgatg caattagtgt aggtgctgct gcagcagaaa ataacatacc
     7921 aatcatactt gcaaatgaaa agagcgaatt gcaaggagct gatgaatttc taaattcatt
     7981 aaatatagag aaatcttata ttattggagg aacagcatcc ctatcaaaca atctagaaag
     8041 taagttaaaa aatccaacta gattatctgg tagtagtaga gacgaaacta attcaaagat
     8101 aatagataat ttttataaaa aagatacttt aaaaaatgca tttgtagtta aaaatggaat
     8161 caagaatcaa aatgatttaa tagatggatt ggcagttggt cctttaggag caaaaactgg
     8221 gtcaccagta attttagttg gtgataaatt agctgatagc caaaaagaag ttcttaaaaa
     8281 taagacttta gaaaaagtaa ctcaagttgg tggaggagca aataaaaatg catttaaaga
     8341 gttagtaaaa ttaaaaagtg ctaaatagag tacttaagta ttaacatata ttagtgtgta
     8401 ttagtaactt atcttaataa aagctgaaaa taattacttt aaattattga taaataagat
     8461 aatcaatgat tgtaaagttt tgttttcagc tttaaattta tgtagtataa gtttaaaaac
     8521 ataaaaaagg gttactatat at
//
LOCUS       DAMJYN010000126         8508 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.131, whole genome shotgun sequence.
ACCESSION   DAMJYN010000126 DAMJYN010000000
VERSION     DAMJYN010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8508)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8508)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8508
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.131"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            237..1223
                     /locus_tag="PC466_003362"
     CDS             237..1223
                     /locus_tag="PC466_003362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDF2770715.1"
                     /translation="MKKITINDIANLAGVSKSTVSRYLNNKDISDSTKEKIKTIIDEY
                     GYEPNAFAQSLRAKKTYFIGIITPCLDSFVKSKIMMAIDEELKELKYTSLIINTNRKI
                     RSEIDSISKLASLKVDGIILIGTEITKEHKNEIEKLDIPMVVVGQKVDGINSIVNDDY
                     GAGYKMGQYIANKGYKNIVYLGVDESDISVGLNRKNGVLNGLKDKGYDAKVFYTDFDQ
                     ETSIQRSGEMLESENPDIIICATDNIAIATMKEINKRGKNIPQDISVAGFGGYDVLSI
                     ISPKLTTIKFENKNAGKVAANTIVNLIQERKEPLLKEIKFELIEGESTINKN"
     gene            1446..1529
                     /locus_tag="PC466_003363"
                     /pseudo
     CDS             1446..1529
                     /locus_tag="PC466_003363"
                     /inference="COORDINATES: protein motif:HMM:NF012587.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIB"
     gene            1560..3041
                     /locus_tag="PC466_003364"
     CDS             1560..3041
                     /locus_tag="PC466_003364"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HDF2770716.1"
                     /translation="MYKEPKYRTILESIKEELNKLRNISLNDKYKPLFHIHPQHGLLN
                     DPNGLAYYNGKYHVFYQWYPYDATHGMKHWAYVSSDDFVNWNREDVALIPIESYESHG
                     AYSGNAIEVDGKLHMYYTGNIKYSAEDRYAYQNLAIMNKDGKITKYENNPIVSEIPKG
                     YTGHVRDPKVFKRKDKYFMLLGAQTSDKKGVIIVYESKNSIDWNFKGELNVKNIDEDF
                     GYMWECPDYINIDEKDILIFSPQGVEPKGFDYQNIYNVVYAIGNMDLDNLTFEIDTMK
                     ELEKGFDFYAPQTFIKDSQIILFAWAGMGEVLYPTDKNKWAHCLTVPRKLNIKNNKLL
                     QMPVDELIKLRYDETSGQNTIKNNINIIENDENVYELNINIKNIDSNKFGLELFSSQD
                     EGVKLEFNKLGNIVTLDRSNFKKVFGVEYGTNRKEYINIDENTNIKVLADRSVLEIFI
                     NDGEVVFTSRIFAKENSNQIRVYSDKIVEYEYTKFKLKQGIEL"
     gene            3067..4038
                     /locus_tag="PC466_003365"
     CDS             3067..4038
                     /locus_tag="PC466_003365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate kinase"
                     /protein_id="HDF2770717.1"
                     /translation="MKKVISIGEALIDFIPNQNGCKLKNVSEFRRVAGGAPANVSVVV
                     AKLGGKSSFISKLGKDAFGDYIIDVLNEVNVNTDYVLRTSKANTGLAFVSLKEDGNRD
                     FSFYRNPSADMLLEADEVKKEWFNNCHILHFCSVDLIDSPMKLAHKKAIEYALESNSI
                     ISFDPNIRLPLWDSEQSCKKAISEFLPFAHIVKISDEELEFMTGENDIEKSLHKLFVG
                     NVELVLYTKGKDGVDAYTKKVKGMCKGVKVNAIDTTGAGDSYIGSFLYTLLYKQITLN
                     DIKEMKQETLNEYLEFSNYYAARSTTIKGAISSYATKEEITEFIKNL"
     gene            complement(4294..4896)
                     /locus_tag="PC466_003366"
     CDS             complement(4294..4896)
                     /locus_tag="PC466_003366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HDF2770718.1"
                     /translation="MEICILMGSPKKKGNTAAILKPFIEELENYNSNIEVIWLYDCKI
                     EPCIACKKCQDNLFDFGCYCKDDVQKIFKKILMCDLIVFATPIYSWYCTSPMKALLDR
                     LVYGMNKYYGNEKGPALWAGKPVALITTCGYRPEKGADIWENGMKRYCKHSQLKYIGM
                     LVERDLGKPNFMNKEKEKHSRQFAKQIYYILDNSIEVDNC"
     gene            5177..6388
                     /locus_tag="PC466_003367"
     CDS             5177..6388
                     /locus_tag="PC466_003367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal-dependent decarboxylase"
                     /protein_id="HDF2770719.1"
                     /translation="MYSNEDYKFIEENAPCYIYDETNIIEKCKELKNNILGFDFLYSI
                     KTNPYNKIVKSIAEQGFGADASSTNEVMISSECGVSKYDIYYSSPGKTEIDIETVLDK
                     CIIIADSITEIELINKISKKHNQKVKIGIRINPDFTMDDDSAKSSKFGIDIEDMSSVF
                     KMLSMCDYVSVVGIHIHIKSQVLDFEKLGHYYEKCFFIALNLNKSKYINIEFINFGSG
                     LGVAYDNLRENPLNLKELSKLTQKIVFTNSNTLKSRLLIESGRFIVCKSGNYYVKIVD
                     IKVSRGKKYLIVKNGLNGFMRPIISNLIENITCGVELEGQEPLYTSNHAFSLSVLNNL
                     KEEEYVNVVGNLCTSLDVIANNVKLKKANIGDLISISNAGSYSYSLSPLLFSSYEFPK
                     QYYKRKDGYIE"
     gene            6456..6653
                     /locus_tag="PC466_003368"
     CDS             6456..6653
                     /locus_tag="PC466_003368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug transporter"
                     /protein_id="HDF2770720.1"
                     /translation="MELWKRNLFVCWIGMFFSSIGMSQIAPILPLYIKQLGVTDVSLI
                     QQYSGIIFGCTFVVAAFFSPI"
     gene            6687..7658
                     /locus_tag="PC466_003369"
     CDS             6687..7658
                     /locus_tag="PC466_003369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2770721.1"
                     /translation="MLLRASIGMGIVIFTMAFVQNVYQLLGLRILQGVFTGYATACTT
                     LIATQTDKNHSGWALGTLATASTTGSLIGPTVGGYIESILGLKSTFIITGGLLFVSFI
                     ISILFVVDNFKPKEIKESISIPKEQLNILPNKFLIASIFVTTFITQLALYSIEPIVTI
                     YISQLTNFASNVALIAGLTFSASGLANLLAAQKLGKMSDKIGPQKVLLISLLWAGIIF
                     IPQAFVKTAWQLMLLRFLLGLSVAGLNPSVNSLLKKIAPEEYVGKIFGYNASAQYIGC
                     SSGAFLGGQISAHLGIRTVFFSTSLLLFMNALWMYKFTGLFIKDKTK"
     gene            7845..8222
                     /locus_tag="PC466_003370"
     CDS             7845..8222
                     /locus_tag="PC466_003370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF2770722.1"
                     /translation="MTISKIPQAELKVMKFIWEKNDTVTSKETIEAMERKYGWKQTTT
                     LTLLSRLVKKHFLSAEKIDRYTHYTIVVGHKEYLSVETKDFLSNIHDNSLQSLISALH
                     DDEVVDKDMLDLFESHFKNLEEE"
BASE COUNT         3456 a          879 c         1359 g         2814 t
ORIGIN      
        1 ttatattata aataaattag agtatttatc aattcatagt agataaaatt gaaattaaat
       61 ataacaacaa aaaatgaaaa ttacaattaa tttaatgtta aagactcaat tatttggatg
      121 tggaatggat agtacaagta gtatataaaa agtattgact ggacaaataa ctatatttta
      181 ttttaaatat ataatataat gtaataaaat atatcaaatg tagaaggtga taacctatga
      241 aaaaaataac aataaatgat attgctaact tggcaggagt atctaaaagt actgtatcaa
      301 gatatctaaa taataaagat atcagtgatt ctactaaaga gaaaataaag acaataatag
      361 atgaatatgg atatgagccg aatgcatttg ctcaaagttt gagagctaaa aaaacatact
      421 ttattggtat tataacaccg tgtttagatt cttttgtaaa atctaaaatt atgatggcaa
      481 tagatgaaga actcaaagaa ttaaaatata catcactaat tattaatact aatagaaaaa
      541 taaggtcaga aatagatagt atatcaaagt tagctagtct aaaagttgat ggaataatac
      601 taattggtac cgaaataact aaagaacata agaatgaaat tgaaaagtta gatataccaa
      661 tggttgtagt tggacaaaaa gttgatggta tcaatagcat agtgaatgat gattatggag
      721 caggatataa aatgggtcaa tatattgcta ataaaggtta caaaaacatt gtatatttag
      781 gtgttgatga aagtgatata tcagttggtt taaatagaaa aaatggagta cttaatgggt
      841 taaaagataa agggtatgat gcaaaagtat tttatactga ctttgaccaa gaaacgtcta
      901 tacaaagaag tggagaaatg ctagaaagtg aaaatccaga tataataata tgtgcaactg
      961 ataatatagc aatagcaaca atgaaagaaa tcaataagag aggtaaaaat ataccacaag
     1021 atatatctgt agctggattt gggggatatg atgtattgtc tattataagc cctaaactta
     1081 caacaataaa gtttgaaaat aaaaatgcag gtaaagtagc agcaaatacg atagtgaact
     1141 taatacaaga aagaaaagaa ccactattaa aggagattaa atttgaatta atagaaggtg
     1201 aaagtacaat aaataaaaat taagatacac attacatata ttagtaatgt gtattttttt
     1261 actaaaaaaa ctataattct aaaaattagg aaaacttttt tgaaagaaat attgcatctg
     1321 aaataaattt atgctaatct ttaattaaac cggtttcgaa accggtttaa ttaaaccgaa
     1381 agaatagcac aatgagtgca aaaataactg attgtaacaa agtatcaaag taattattag
     1441 agtacatagg aaataaacaa aatataaaag gtgtagcaca ttgtgtaaca agattaagaa
     1501 ttgttttaga tagtaataat aaagcaaata taaaattaca aaagaaaagg aataaaaata
     1561 tgtacaaaga gcctaaatat agaaccatat tagaatcgat aaaagaagaa ttaaataaat
     1621 taagaaatat atctttaaat gataaatata aaccactatt tcatatacat ccacaacatg
     1681 gactacttaa tgatccaaat ggattagcat attataatgg taagtaccat gtattttatc
     1741 aatggtatcc atatgatgca actcatggaa tgaagcattg ggcttatgta agttctgatg
     1801 attttgtaaa ctggaataga gaagatgtag cattaatacc aatcgaaagt tatgaatctc
     1861 atggagcata ttcaggtaat gcgatagagg tagatggaaa attgcatatg tattatacag
     1921 ggaatataaa atatagtgca gaagatagat atgcatatca aaacttagct ataatgaaca
     1981 aggatggtaa aataactaaa tatgaaaata atccaatagt aagtgaaata ccaaaaggat
     2041 atacaggaca tgtaagagac ccaaaagtat ttaaaagaaa ggataaatac tttatgttac
     2101 ttggagcaca aacaagtgat aaaaaaggag ttataatagt atatgaatct aaaaactcta
     2161 tagattggaa ttttaaagga gaattaaatg taaaaaatat agatgaagat tttggttaca
     2221 tgtgggaatg tccagattat attaatatag atgaaaaaga tatattaata ttttcgccac
     2281 aaggagtaga acctaaagga tttgattatc aaaatatata taatgtagta tatgctattg
     2341 gtaatatgga tttagataat ttaacatttg aaatagatac aatgaaagaa ctggaaaaag
     2401 gatttgattt ctatgctcca caaacattta taaaggactc acaaataata ctatttgcat
     2461 gggctggaat gggagaagtt ttatacccta cagataaaaa caaatgggca cattgtctaa
     2521 ctgttccaag aaaattaaat ataaaaaata acaagctatt gcaaatgcct gtagatgaat
     2581 taattaaatt aagatatgat gaaacaagtg ggcaaaatac tataaagaat aatatcaata
     2641 ttatagaaaa tgatgaaaat gtatatgagc ttaatattaa tataaaaaat attgacagca
     2701 ataaatttgg gctggaatta ttttcatcac aagatgaagg tgtaaaatta gaatttaaca
     2761 aattaggaaa cattgtaact ttagacagaa gcaactttaa aaaagttttc ggtgttgaat
     2821 atggaacaaa tagaaaagaa tatataaata ttgatgaaaa tactaatatc aaagtactag
     2881 cggatagaag tgttttagaa atttttataa atgatggaga agtagtattt actagtagaa
     2941 tatttgctaa agaaaattct aatcaaataa gggtttatag tgataaaata gtagagtatg
     3001 agtatactaa atttaaatta aagcaaggta ttgaattata aaaacacatt ataaggggta
     3061 gaaaagatga aaaaagtaat tagtatagga gaagctttaa tagactttat acctaatcaa
     3121 aatggttgta aattaaaaaa tgtatcagaa tttagaagag tagcaggagg agctccagca
     3181 aatgttagtg ttgttgtagc aaagcttgga ggaaaatcaa gttttatatc taagttagga
     3241 aaagatgcat ttggtgatta tataatagat gtattaaatg aagtaaatgt aaatactgat
     3301 tatgtattga gaacaagtaa agcaaataca ggacttgctt ttgtatcatt aaaagaagat
     3361 ggtaatcgtg atttctcatt ttatagaaat ccaagtgcag atatgctttt agaagctgat
     3421 gaggttaaaa aagagtggtt taataattgt catatcttac atttttgttc agtagattta
     3481 atagatagtc caatgaaatt agcacataaa aaagcaatag aatacgcact tgaaagtaat
     3541 agtataataa gttttgaccc taatataaga ttacctttat gggatagtga gcaatcttgt
     3601 aaaaaggcaa tatcagaatt tttacctttt gctcatattg ttaagatatc tgatgaagaa
     3661 ttagaattta tgacaggaga aaatgatata gaaaaatcat tacataaact ctttgtgggg
     3721 aatgttgaac tagtattata tacaaaagga aaagatggag tagatgcata cactaaaaaa
     3781 gtaaaaggta tgtgtaaagg ggttaaagta aatgcaatag atacaaccgg agcaggagat
     3841 tcttatatag gttcattttt atacacctta ttgtataaac aaataacatt gaatgatata
     3901 aaagaaatga aacaagaaac gttaaatgag tatttagaat tttctaatta ttatgcagct
     3961 cgtagtacaa ctattaaagg tgcgataagt tcatatgcaa caaaggaaga gataactgaa
     4021 tttataaaaa atttatagta ggaatgagta ataggttttg aaggaagtaa catgtaaaga
     4081 gtttttaagg atgtttacta tgaaaataat taacatataa aaagcaataa agaggctgtc
     4141 tcaaaataga tataagcctc tttatcattg ttgaaatgat aaaaaatatt ttaattattg
     4201 ttacttttta gaagaatata tatcttattt taaataagca aattatgtaa gatttattta
     4261 tattatcaat actttacttg gagtattatg tctttagcag ttatctactt caattgaatt
     4321 atctaaaata taataaattt gttttgcaaa ttgacgagaa tgtttttctt tttctttatt
     4381 cataaaatta ggtttaccta aatcacgttc aacaagcatt cctatatatt ttaactgtga
     4441 atgcttacag tagcgcttca taccattttc ccaaatatca gcaccctttt caggtctata
     4501 tccacatgtt gtaataagtg ctactggttt tcctgcccat agagcggggc ctttctcatt
     4561 accatagtac ttattcattc catacaccaa tctgtcaagt agtgctttca ttggagaagt
     4621 gcagtaccaa gaataaattg gagtagcaaa aacaattaaa tcacacataa gaattttctt
     4681 gaaaattttc tgaacatcat ctttacaata acatccaaaa tcaaataagt tatcctgaca
     4741 ttttttacaa gcaatacatg gctctatttt acaatcatat aaccatatta cttcaatatt
     4801 tgaattataa ttttctaatt cctcaataaa aggttttaaa atagcagcag tattaccttt
     4861 tttcttagga cttcccataa gaatgcatat ttccatattg atacctccac agtattttaa
     4921 aatagttttt agtgcttaat atagttttag gatactatga gaatacgtta acaacaatac
     4981 actttgtata tttttaataa aattgaaaca aattgtttta tcaataaaag ttggaatgta
     5041 tctataatta aaaatatttt aggtatgttt ttacatatat gtgtgtagtt aactatggta
     5101 atttattgta aaattatctt ataggattat aattgcttaa tttatgatta tatttaaaat
     5161 cttggaggta aaaaatatgt actcaaatga agactataaa tttatagaag aaaatgcacc
     5221 atgttatata tatgatgaga ctaatataat tgaaaaatgt aaggaattga aaaataatat
     5281 tttaggtttt gattttttat attctataaa aacaaatcca tataacaaaa ttgtaaaaag
     5341 cattgcagag caaggttttg gagcagatgc ttcttcaact aatgaagtta tgatttcatc
     5401 agaatgtgga gtttctaaat atgatattta ttattcatca ccaggcaaaa cagagattga
     5461 tatagaaact gttttagata aatgcataat tattgcagat agtattacag aaatagaact
     5521 tataaataag atatctaaaa agcataatca gaaagttaaa ataggaataa gaataaatcc
     5581 tgattttact atggatgatg atagtgctaa atcaagcaaa tttggtatag atatagaaga
     5641 tatgagcagt gtttttaaga tgttaagtat gtgtgattat gtatctgtag ttgggattca
     5701 tatacatatt aaatctcagg tattggattt tgaaaagtta ggacattatt atgaaaaatg
     5761 tttttttata gctttaaatt taaataaaag taagtatatt aatattgaat ttataaattt
     5821 tggtagtgga cttggagtag cttatgataa tcttagagaa aatccactta atcttaaaga
     5881 gctttcaaaa ttaactcaaa agattgtttt tactaattca aacacactga aatcaagact
     5941 tcttattgaa tcaggacgtt tcatagtttg taaatcaggt aattattatg ttaaaattgt
     6001 agatattaaa gtatcaagag ggaaaaaata tcttattgta aaaaatggac ttaatggatt
     6061 tatgagacct attatttcta atttaattga aaatattact tgtggagtag aattagaagg
     6121 tcaagagcca ttatatacat caaatcatgc cttttctctt tcagtattaa ataatttaaa
     6181 agaagaagag tatgtaaatg ttgttgggaa tctctgtaca tcattagatg taattgcaaa
     6241 taatgttaaa ttgaaaaaag caaatatagg agatttgatt tcaattagta atgctggaag
     6301 ttactcctat tctttatcac cactattatt ttcgagttat gaatttccta aacaatatta
     6361 taaaagaaaa gatggatata ttgagtaaac aataggataa attaataaac ttagtattat
     6421 tgaaaaaatt taaaatgcag ggggtgtaat tctatatgga attgtggaaa agaaatttat
     6481 ttgtatgttg gataggtatg ttttttagtt ctatagggat gagccaaata gcacctatac
     6541 ttccattata tattaaacag ttgggggtaa ctgatgttag tttaatacaa cagtattcag
     6601 gtataatttt tggatgtacc tttgtagtag cagcattctt ttcgccaatt tgagggaaag
     6661 ctgctgataa atatggaaga aaatcaatgc ttttacgtgc aagtattggg atgggaatag
     6721 ttatatttac catggcgttt gttcaaaatg tttatcagtt attaggatta agaatacttc
     6781 aaggagtttt tacgggttat gctactgcat gtactactct tattgcaaca cagacagata
     6841 aaaatcattc aggatgggct ttgggtactc ttgcaactgc atcaactact ggctcattaa
     6901 ttggtccaac agtaggagga tatatagaat caatcttggg tcttaaaagt acatttatta
     6961 taacaggagg attgttgttt gtatcattta tcatctctat tttatttgta gtagataatt
     7021 ttaaacctaa agaaataaaa gaatcaattt ctatacctaa agaacaatta aatatattgc
     7081 caaataaatt tttaattgca tctatttttg taaccacatt cattactcaa ctagctttat
     7141 actctataga accaattgta accatatata tatcacaact tacaaatttt gcatcaaatg
     7201 tagctttaat agctggattg acattttctg catcaggatt agcaaattta ttagcagctc
     7261 aaaaacttgg aaaaatgtca gataaaatag gtcctcaaaa agtattgtta atttcacttt
     7321 tatgggctgg gattatattt ataccacaag cttttgtaaa aactgcatgg caactgatgt
     7381 tgttgagatt tttattaggg ttgtcagttg cagggcttaa tccttctgtt aacagcttgc
     7441 ttaaaaaaat tgcaccagaa gaatatgtgg gaaaaatatt tggatataat gcatctgccc
     7501 agtatatagg ttgttcatca ggagcatttt tagggggaca aatatcagca catttaggta
     7561 ttagaacagt atttttttca acaagtttat tgttgtttat gaatgcactt tggatgtata
     7621 aatttactgg attgtttatt aaagataaga ctaaataatc atactattta catttctaat
     7681 tttatgatgt aaaataaata ttttttatgt aatttatcat agaattatat aaaaaataac
     7741 tctatggtaa aaattggaaa atattattat cgacaaaatc tttgacttaa aaactatatt
     7801 gcgatagtat taatttaata aaagtttgag aggggcgtaa ggttatgaca atttcaaaaa
     7861 taccacaagc agaattaaaa gttatgaagt ttatttggga aaaaaatgat acagtaacat
     7921 caaaagaaac tattgaagct atggaacgaa aatatggttg gaaacaaaca actacattga
     7981 cacttttatc aagacttgtt aaaaaacatt ttttaagtgc agaaaaaata gatagataca
     8041 ctcattatac aatagttgtt ggacataagg agtatttaag tgttgagaca aaagattttt
     8101 taagcaatat acacgacaat tctttacaga gtttaatttc agcactacat gatgatgaag
     8161 ttgttgataa agatatgttg gatttatttg aaagtcattt taaaaattta gaagaagagt
     8221 aattatatca ggataaaact ctaagaattt aattaatcta tggctgaaaa ccataaatgg
     8281 tattatttaa tcagctactc actattcata aagtaatatt aaataggttc tctaattagt
     8341 aaaataccta aaataattgg aatagggagt atcaagttaa atgataccac ttatttaaat
     8401 aagaaatgat ttttaaaatt taaaataatt ttataacttg tcaatattca ttaatctaaa
     8461 gtattatttc tatttaacca tatcaaaata tattttacta tttttaat
//
LOCUS       DAMJYN010000127         8503 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.132, whole genome shotgun sequence.
ACCESSION   DAMJYN010000127 DAMJYN010000000
VERSION     DAMJYN010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8503)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8503)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8503
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.132"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            26..2203
                     /locus_tag="PC466_003371"
     CDS             26..2203
                     /locus_tag="PC466_003371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HDF2770723.1"
                     /translation="MYNKYNNLYLLLGKENVNMDSYRQLKAKIPCKETGIEIKRTLCD
                     ICSPGVHCGIDAYVKDGKVIKIEGTKEHPMNKGLLCTKGLCNREYIYREDRIKTPLKR
                     IGKRGEGKFKPISWDEAYREIAEKLNRVKSEYGAKHVAFFTGYGKWYRPFLQRFASSF
                     GSPNYGTESSSCSTSAQMAGNVATGRNFTMQDMENAKTYLGWGFNPYYSKFLNSVNLI
                     KLKEKGLKFIIVDPRITPTTQKLADLHLRIKPGTDGALALGMANLFIQKDLIDREYIE
                     KHVHGFNEYKEYVKLFDLDTVSRITGVSKDNIVKAVEMLSQGPFCINESAAPIVHHQN
                     GFQNYRAMMSLSAITGNYDRIGGNIPKQDYFAGKIGGFQTLEKEFVKEVLPKNINERI
                     GGERFPLWNEMVTQFQAMDLPRQIEEKTPYEIRALFCHGINARMFPNSGRLFKALHSV
                     DFFVNIDLFMTDTSKYADILLPACTSFEREECKSYPGGYITYTKKVIDKLYDSKSDVE
                     ILSDLANVMNIDDDLLKAGYEASIRHMFKKTCVDVDKLKESDLPLKCKDFKPYIVGSY
                     TREGYDTSTSRFELKSTIIEKYKDFGLDALPTYRGFNDNIDNEYTHLLTSGARISNAL
                     HSRLHDIKLSRILKNEASCDISSLDAKELGVISGDYIKITTKIGSLDVKVNVTDRVLY
                     KNIHMYHGYRESDINSIIDDNFDPYSGFPAYRSCKCKIEKMNR"
     gene            2217..2639
                     /locus_tag="PC466_003372"
     CDS             2217..2639
                     /locus_tag="PC466_003372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDF2770724.1"
                     /translation="MKSLFKFNKELCTACGACLLACIDQNDNNIDNGELFRHVFTIEE
                     GENIEYFSLACIHCNEPKCLGACPKNCFKKEEGFVVLDNQNCIGCKLCEKACEYGALI
                     YGNDGKANKCNGCIERYKCGMDSPCVMVCPTGALKFNK"
     gene            3046..3849
                     /locus_tag="PC466_003373"
     CDS             3046..3849
                     /locus_tag="PC466_003373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HDF2770725.1"
                     /translation="MKKLKLIIMLALVLALLITGCSSGNNKNKEEQKTIRVATSGTYY
                     PFAFKDKDKLKGFEVDFWDEFAKRTNCKVEWVLTDFSGLFGLLEADKADVVSAQLTAT
                     PEREKKYAFSDAYNYSGTNIIVREDDTSIKSIDDLVGKKVGVGTGAVANEILKEKYPN
                     DEIKIVNYSSATLKGNYQDLEMGRLDAVVAQDVEALIAIKEQKLNLKMVEPPIQFGAC
                     SFAIQKNEKGEKWTKEINEVIEEMHKDGTLTKISEAWLGKDITKEPINE"
     gene            3842..4510
                     /locus_tag="PC466_003374"
     CDS             3842..4510
                     /locus_tag="PC466_003374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HDF2770726.1"
                     /translation="MSNFNFEFCLSIFPFLIKALGITILISIVAFFLSILLGVILAFF
                     TQTKSKVLQYITRVYVSFFRGTPLLIQIFFFYFGFPMIFSFMKDCSPYLAIVICLGVN
                     SSAYMTEIIRASIESVDKGQQEACYAFGLSKYQSMVKIILPQAATSAVPPIVSCTLDI
                     IKGSSLGLTIGIQDLMGVAQVEAASSFKYFEIYMITILIYWAVSIILSNIQSKVEKRI
                     GKAY"
     gene            4746..5408
                     /locus_tag="PC466_003375"
     CDS             4746..5408
                     /locus_tag="PC466_003375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HDF2770727.1"
                     /translation="MIFNMKYFLELFPIIMKSFNVTVILAISSLVFSLIIGTIVALSS
                     YYKVKVLNQICKVYVSIFRGTPLMPQLFFLYFGLAYMNDFVKNMDPVFATSIVLSLNM
                     GAYMSETIRASILSIDKGQIEAAYVMGLTNLQTMKRIVIPQAVRVALPSLFNNFIDLI
                     KGSSVAFVVGVNDIMGAAKSQGALSFKFFEVYGAVMVIYWCIITPLGWGQKKLEKKIS
                     NY"
     gene            5468..6265
                     /locus_tag="PC466_003376"
     CDS             5468..6265
                     /locus_tag="PC466_003376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HDF2770728.1"
                     /translation="MVKRNIIKCLVAVLSLTFVVAGCSKKEEVKDEKVITVASSNSAD
                     PYSYVDNGEHKGFEVDMWKEIGKRSGYKIKMEPTGFSSIFGMLDSGKVDVAANFFGMS
                     KERLEKYDASIPYGSDSVCIAVKDGNNEINKLEDLKGKVVAVSEGSQGQQVAASVNKD
                     NLFEEKVYGDGTNGLQDLDLGRVSAWIDAELTVVGDAKKANMKVRVLDEKLSVTNIAY
                     FFKKNDEKSKTIKEDVNKAIEEMLSDGTVKKISEKWFGMDVSADIQK"
     gene            6398..7573
                     /locus_tag="PC466_003377"
     CDS             6398..7573
                     /locus_tag="PC466_003377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2770729.1"
                     /translation="MIETKIKSIALKNREKIIKIRRQIHSNPELAFKEFKTSKLIKEE
                     LNKLKIEYIDVAGTGVLATIKGKNNGGKTILLRADMDALPIKEENDLEFKSINDNMHA
                     CGHDAHVSWLLGTAMILNDIKEELNGNVKLLFQPGEEKGGSDIVIKENVLEGVDALAT
                     GHCWPTIESGKIGIARNCAMAATNTFEITIIGKGGHGAEPHNCIDPIAVGNAVYSSIQ
                     QIVSRKIDPVVPVVVSVCSFNSGVSKNIIPDVCTLQGTIRAISKEQVIEVSKILENIV
                     RNVCRAYGADCKFEKSTGGDAVINDKNMIELGRESACKILGVENVEIIDFPAMTGEDF
                     AIYMKEKPGLFMYIGVGNKEKNINYRLHSNKFNIDEKCLSIASSLFSQLAVDYLCQL"
     gene            7682..8431
                     /locus_tag="PC466_003378"
     CDS             7682..8431
                     /locus_tag="PC466_003378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HDF2770730.1"
                     /translation="MIKVENLHKSFKGTEVLKGINLEINQSEVVAILGPSGTGKSTLL
                     RCLNYLVEPTKGKIMIGDVKVDVEKATKKDIANLRKHTSMVFQNYNLFKNKTALENVM
                     EALIVVHKKSNKEAREISLKLIDKVGMLDRKDFYPSKLSGGQQQRIGIARAMAVNPNV
                     ILFDEPTSALDPELVGEVLSVIKSLAKEGITMLIVTHEINFAKEVADKIIFMDNGVIA
                     EEGTPDEIFNNPKNERTAKFLNIVRKEEVFS"
BASE COUNT         3372 a          863 c         1584 g         2684 t
ORIGIN      
        1 aaagtatgat atttgaataa aaagaatgta taataagtat aataatttgt atttattatt
       61 gggaaaggaa aatgttaata tggatagtta tagacaactt aaagctaaaa taccctgtaa
      121 ggaaacaggt atagaaataa agaggacttt atgtgatatt tgttctccag gagtacattg
      181 tggaattgat gcatatgtta aagatggtaa agtaataaaa atagaaggta caaaagaaca
      241 tccaatgaat aaagggttgt tatgtaccaa aggtctttgc aatagagaat atatatatag
      301 agaagataga ataaaaacac ctctaaaaag aattggaaaa agaggtgaag gaaaatttaa
      361 accaatatca tgggatgaag cttatagaga aatagcagaa aaattaaata gagtaaaatc
      421 tgagtatgga gcaaagcatg tagctttttt tacgggttat ggaaagtggt atagaccttt
      481 tttgcaaagg tttgcatctt catttggttc acctaattat ggtacagaat ctagttcatg
      541 ttcaacatca gcacagatgg ctggaaatgt tgctactgga agaaacttta caatgcaaga
      601 tatggagaat gcaaaaactt atttagggtg gggatttaat ccatactact ctaaattttt
      661 aaatagtgtg aatctaataa aattaaaaga aaaaggtcta aaatttataa ttgtagaccc
      721 tagaataaca ccgacaactc aaaaactagc agatttacat ttaagaatta aacctggaac
      781 tgatggagct ttagctcttg gaatggcgaa tctatttata caaaaggatt taatagatag
      841 agaatacata gaaaagcatg tacatggatt taatgaatat aaagaatatg taaaattatt
      901 tgatttagat actgtaagta gaattacagg agtttctaaa gataatatag taaaagctgt
      961 tgagatgttg tcacaaggtc cattttgtat aaatgaaagt gcagctccaa tagttcatca
     1021 tcaaaatgga tttcaaaact atagagcaat gatgtcttta tctgctataa caggtaatta
     1081 tgatagaata ggtggaaaca taccaaaaca agattacttt gctggtaaga taggtggatt
     1141 ccaaacacta gaaaaagagt ttgtaaaaga agttctacct aaaaatataa atgaaagaat
     1201 tggtggagaa agatttcctc tatggaatga aatggtaact caatttcaag ctatggattt
     1261 acctaggcaa atagaagaaa agacaccata tgaaataaga gctttgtttt gtcatgggat
     1321 aaatgctaga atgtttccta attcagggag actttttaaa gcgttgcata gtgtagattt
     1381 ttttgtgaat atagatttat ttatgacaga tacatcaaaa tatgcagata tacttttacc
     1441 tgcgtgtaca tcatttgaga gagaagaatg taagagttac ccaggagggt atattacata
     1501 taccaaaaaa gttattgata aattatacga ttcaaaatca gatgtagaaa tactttcaga
     1561 tttagcaaat gttatgaata tagatgatga tttattaaaa gcaggttatg aagcaagtat
     1621 aagacatatg tttaaaaaga cgtgtgtaga tgtagataaa cttaaagaaa gtgatttacc
     1681 attaaaatgt aaagatttta agccatatat agtaggctca tatacaagag aggggtatga
     1741 tactagcact tctaggtttg aattaaaatc tacaattatt gaaaaatata aagattttgg
     1801 actggatgca ctaccaacat atagaggatt taatgataat atagataatg aatatactca
     1861 tttattgaca tcaggagcaa gaatttcaaa tgcactacat tcaagacttc atgacatcaa
     1921 actttcaaga atattaaaaa atgaagctag ttgtgatatt tccagcttgg atgcaaaaga
     1981 attgggtgtt atcagtggag attatataaa aataactact aagataggaa gtttggatgt
     2041 aaaagtcaat gttactgata gagtcttata taagaatata catatgtatc atggatatag
     2101 agaatctgat ataaatagta ttattgatga taattttgac ccttatagtg gattccctgc
     2161 gtatagaagt tgcaagtgta agattgaaaa aatgaataga taaatggaga gatataatga
     2221 aaagtttatt taaatttaat aaagaattat gtacagcatg tggagcatgt ttgcttgcat
     2281 gtatagacca aaatgataat aatatagaca atggtgaact ttttagacat gtatttacaa
     2341 tagaggaagg tgaaaatata gaatattttt cattagcatg tatccattgt aatgagccaa
     2401 aatgtttagg tgcatgtcct aaaaattgtt ttaaaaaaga agaaggattc gttgtattag
     2461 acaatcaaaa ctgtataggg tgtaaacttt gtgaaaaagc ttgtgaatat ggagccttaa
     2521 tttatggaaa tgatggtaag gcaaataagt gtaatggttg tattgagaga tataagtgtg
     2581 gtatggattc accttgtgta atggtatgtc ctacaggagc attaaaattt aataaataaa
     2641 ttaaatatag agagtgactt atacttggta taagatattt ttacaaaaag ctatattgag
     2701 tttgttataa taaaaactca atatagcttt tttatggata tagttggata ctataatgtg
     2761 atttttagta atagtttttt gctattggac aaagactgta aaacatatta aacttatgtt
     2821 gttcaaagtc gaagtataat ataataacta gaaaattgat ttatagtgtt ataaaagcaa
     2881 atttagtaag gtataaaata agaggcaatc ttttactaca gtatcaatat ttgggagtta
     2941 tgttatggca gagccattaa acaattataa tggtacaagt gattcaacct ttgaaaatgt
     3001 attatataaa aaattaaaat aagattaaaa aggagagaat aaattatgaa aaaacttaaa
     3061 ttaattatta tgcttgcctt ggtattagca cttttaatta caggatgttc atcaggaaat
     3121 aataaaaata aagaagaaca aaaaactata agagttgcaa catcaggaac atattaccct
     3181 tttgctttta aagataaaga taaacttaaa ggatttgaag tagatttttg ggatgaattt
     3241 gctaaacgaa ctaattgtaa agttgaatgg gtattaactg attttagtgg attatttgga
     3301 ttattagaag ctgataaagc agatgttgta tctgctcaac ttactgcaac acctgaaaga
     3361 gagaaaaaat atgctttttc agatgcttat aattatagtg gaacaaacat tattgttaga
     3421 gaagatgata ctagtataaa atcaatagat gatttagttg gcaagaaagt aggtgtgggt
     3481 actggagcag tagcaaatga aatactaaaa gaaaagtacc caaatgatga aataaaaata
     3541 gtaaattatt caagtgcaac tcttaaaggg aattatcaag atctagaaat gggaagatta
     3601 gatgcagtag ttgcgcagga tgttgaggct ttaatagcta taaaagaaca aaaattaaat
     3661 cttaaaatgg tagaacctcc aattcaattc ggagcctgtt cttttgcgat tcaaaaaaat
     3721 gaaaaaggtg aaaaatggac aaaagaaatt aacgaagtaa ttgaagagat gcataaagat
     3781 gggactttga ctaaaatatc tgaagcctgg ctaggaaaag acattactaa ggagcctatt
     3841 aatgagtaat tttaattttg aattttgtct aagtatattt ccatttttga ttaaagcatt
     3901 gggaataaca atactaatat ctattgttgc atttttttta tcaatattat taggtgtaat
     3961 acttgccttt ttcacacaga caaaatcaaa agttttgcaa tacataacaa gagtgtatgt
     4021 ttcattcttt agaggaacac cacttttaat tcaaatattt ttcttttact ttggatttcc
     4081 aatgatattt tcttttatga aagattgttc accttattta gcaatagtaa tttgtttagg
     4141 tgtaaattca tctgcatata tgactgaaat tatacgagca tctattgaga gtgttgataa
     4201 aggacaacag gaagcatgtt atgcttttgg gttaagtaaa tatcagtcaa tggttaaaat
     4261 aattctacct caagcagcta catctgcagt acctcctatt gtaagctgta cactggacat
     4321 aattaaaggt tcttctttag gtctaactat aggaatacaa gatttaatgg gagtagctca
     4381 agtagaggct gcttcaagtt ttaaatattt tgagatatat atgataacga tattaattta
     4441 ctgggcagta tctataatat tgagtaatat acaaagcaaa gttgaaaaaa gaataggaaa
     4501 ggcatattag atttcaatat ttaaaaatgg gatgatgtag atatattatt acttgtaaat
     4561 aaatttttaa ttttagaaaa ataaacttag taatctaaat tattgagaaa atatagtatc
     4621 aaaatggact gtataatcaa gttaaaaaat agtttttcta ttgaaaaaat aaataaaatt
     4681 ctattgtaat ttaatattcg acaaagtttt ataaaaaaca acattaagct agggggactt
     4741 attttatgat ttttaatatg aaatattttt tagaattatt tccaataata atgaaatcgt
     4801 tcaatgtaac tgtaattttg gcaataagtt cattagtatt ttcattaatt ataggtacaa
     4861 tagtagcatt atcatcttat tacaaagtga aagtattgaa tcaaatatgt aaagtatatg
     4921 tatctatctt tagaggtacg cctcttatgc cacagttatt ctttttatat tttggactag
     4981 cgtatatgaa cgattttgtt aaaaatatgg acccagtatt tgcaacatct atagtactta
     5041 gtttaaatat gggagcttat atgtccgaaa cgataagggc atctatactt tcaattgata
     5101 aaggtcagat agaagcagca tatgtaatgg gattaacaaa tttacaaaca atgaaaagga
     5161 tagtgatacc acaggccgta agagttgcac tgccatcatt attcaataat tttatagatt
     5221 taattaaagg gtcttctgta gcttttgttg ttggagtaaa tgatataatg ggtgctgcca
     5281 aatcacaagg agcgttgagt tttaagttct ttgaagtgta tggagcagtt atggtaattt
     5341 actggtgcat aataactcct ttagggtggg ggcaaaaaaa attagaaaag aaaataagca
     5401 attattaagt tattaagaaa atacataaaa gtatttttat ataaaaaatg gtgtgaggag
     5461 aagagatatg gtaaaaagaa atattataaa atgtttagtg gcagttttat cgttaacatt
     5521 tgtagttgct ggttgttcaa aaaaagagga agtaaaggat gaaaaagtta taactgtagc
     5581 ttcatctaat tcagctgacc catattctta tgttgataat ggtgagcata agggttttga
     5641 agttgatatg tggaaagaga ttggtaaaag aagtggatat aagataaaaa tggaaccaac
     5701 aggttttagt tctatatttg ggatgttaga ttctggtaaa gttgatgtgg cagccaattt
     5761 ctttggaatg tctaaagaaa gattagaaaa atacgatgct tctatacctt atggttctga
     5821 ttctgtatgt atagctgtaa aagatggaaa caacgaaatt aataaacttg aagatttaaa
     5881 aggaaaagtt gtagcagttt cagaaggttc tcaagggcaa caggttgcag ctagtgttaa
     5941 taaagataat ttgtttgaag aaaaggttta tggtgatgga actaatggtc ttcaagattt
     6001 agatttagga agagttagcg catggattga tgcagaactt actgttgtag gagacgctaa
     6061 aaaagctaat atgaaggtaa gagtattaga tgaaaaatta tcagttacta atatagcata
     6121 cttctttaag aaaaatgatg aaaaatctaa aactataaaa gaagatgtaa ataaagcaat
     6181 agaagaaatg ctttcagatg gaacagtgaa aaaaatatct gaaaaatggt ttggaatgga
     6241 tgtaagtgct gatatacaaa aataaatact ttaaaattaa aatataaaac tgtgataact
     6301 atagataagt atactaaatt tatctatagt tatctgtgta ttacaatgta tttagattag
     6361 tctttataaa ttaaaatgag ttatggaggt cttgcaaatg attgaaacta aaataaaatc
     6421 cattgcacta aaaaatagag aaaaaatcat aaaaataaga cgacagatac acagtaatcc
     6481 agagttagca tttaaagaat ttaaaacatc caaacttata aaagaagagt taaataaact
     6541 taaaatagaa tacatagatg ttgctggtac aggagtatta gctactataa aaggaaaaaa
     6601 taatggtggg aaaactatat tgcttagagc ggatatggat gcccttccaa tcaaagagga
     6661 aaatgattta gaatttaaat caataaatga taatatgcat gcttgtgggc atgatgccca
     6721 tgtttcatgg ttgttaggaa cagcaatgat tttaaatgac ataaaagaag aattgaatgg
     6781 aaatgtaaaa ttactatttc aacctggcga agaaaaaggt ggttctgata ttgtaattaa
     6841 agaaaatgta cttgaaggtg tggatgcatt agcaactggt cattgttggc caactattga
     6901 atcaggaaaa attggaatcg ctagaaattg tgctatggca gcgactaata cttttgaaat
     6961 aacaataatt ggcaagggcg ggcatggagc agagcctcat aattgtatag acccaattgc
     7021 agttggaaat gcagtatatt catccattca acagatagtt tcaagaaaaa ttgacccagt
     7081 tgtacctgta gtagtgtctg tttgttcttt taattctggt gtttctaaaa atataatacc
     7141 agatgtatgc acacttcaag ggactattag agcgataagc aaggaacaag taattgaagt
     7201 aagtaaaatt ctagaaaata tagtaagaaa tgtatgtaga gcatacggag cagattgcaa
     7261 atttgaaaag agtacaggag gagatgctgt tataaatgac aaaaacatga tagagctagg
     7321 aagagaaagt gcttgcaaaa tacttggagt tgaaaatgtt gaaataattg attttcctgc
     7381 aatgacaggt gaggattttg ctatttatat gaaagaaaaa cctggtttat ttatgtatat
     7441 aggtgtagga aataaagaaa aaaatataaa ctacagattg catagtaaca agtttaatat
     7501 agatgaaaaa tgtcttagta tagcatcttc attattctca caacttgcag tagattattt
     7561 atgtcaacta tagagtacat tcataaaaat atatttagcc tatttttaaa tttaatgcta
     7621 gtatattaat tttgatgtag aacatattat ttattatatt tatttaaaaa ggtggataac
     7681 aatgataaaa gtagaaaatt tacataaaag ttttaaaggg acagaagttc ttaaaggtat
     7741 aaatttagag ataaatcaaa gtgaagtagt agctatactt ggaccatctg gaacaggtaa
     7801 atctacgtta cttagatgtt taaattattt agttgagcct acaaaaggaa agataatgat
     7861 tggtgatgta aaagtagatg tagaaaaagc aacaaaaaaa gatatagcca atttaagaaa
     7921 acatacatct atggtatttc aaaattataa cttatttaaa aataaaacag cattagaaaa
     7981 tgtaatggag gcattgatag tagtacataa aaagagtaat aaagaagcta gagaaatatc
     8041 tttaaaatta atagataaag taggtatgtt ggataggaaa gatttttatc catcaaaatt
     8101 gtctgggggg cagcaacaaa ggataggtat agcaagagcg atggcagtaa atccaaatgt
     8161 aatattattt gatgagccaa catctgcact tgacccagaa cttgttggag aagttttaag
     8221 cgttataaaa tcgcttgcga aagaaggaat aacaatgctt attgtaactc acgaaataaa
     8281 ttttgcaaaa gaagttgctg ataaaattat atttatggat aatggtgtaa tagctgaaga
     8341 aggaactcct gatgaaatat ttaataatcc taaaaatgaa agaactgcaa aatttttaaa
     8401 tatcgttagg aaagaagaag tatttagtta aaagtgtata aattaagtat tagaagatat
     8461 gtaagatact cccattaaat ttataagtta gataataaat tta
//
LOCUS       DAMJYN010000128         7995 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.134, whole genome shotgun sequence.
ACCESSION   DAMJYN010000128 DAMJYN010000000
VERSION     DAMJYN010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7995)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7995)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7995
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.134"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            56..517
                     /locus_tag="PC466_003379"
     CDS             56..517
                     /locus_tag="PC466_003379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF2770731.1"
                     /translation="MNSNSEEKLNDVFLQLMRIYFIRTHFYFDKLGLYHGQPQILFSL
                     KMKDGQSQKELADKRKVKASTTTVMIKRMEKAGLVERKQDEKDQRVSRIFLTDKGLEI
                     CNKVEEFNKELEREFFLGFSEEEKIVLRRLLMQVRDNLKAGCHKHEDEKYF"
     gene            585..2831
                     /locus_tag="PC466_003380"
     CDS             585..2831
                     /locus_tag="PC466_003380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011009877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2770732.1"
                     /translation="MFKLIKYLKKSALSIVIIVCLLVIQAVCDLSLPEYTSNIVNVGI
                     QQGGVENSVPSVIRESELNKITLFMDKSSKDKVLDNYTLLNKKDYVKYKDKYPGLKDE
                     SLYELNTKDKDTIDDLNVIFGKAILIVSGLEGDSKEVKAMKAQLMSKLPPQATQSGDV
                     DIFKLLSAMPKEQLDTLTKEMSKGFESMPESMITQSSVSYVRSEYEKIGIDTEKTQNN
                     YILFTGAKMLGIAMISMVATITVGFLAARVAASVGRNLRSGVFRKVMSFSNTEMNEFS
                     TASLITRSTNDIQQIQMLMVMLLRIVFYAPIMAIGGVIKVLNTNTSMAWIIAVAVVAI
                     LSLIVVLFSVVMPKFKLVQKLVDKLNLVSREIITGIPVIRAFSTEKHEEERFDKANKN
                     LTKTNLFVNRVMTCMMPAMMLIMNLITVLIVWRGAYSVDSGAMQVGDMMAFIQYTMQI
                     IMSFLMISMVSIMLPRASVSATRIDEVLVSDISIKDPEKSEAQEFKEDKKGLVEFKNV
                     SFMYPDAEEPILTNISFTAKPGETTAFIGSTGSGKSTLINLIPRFFDVTEGEILLGGV
                     NIKNVSQHDLREKIGYVPQKGVLFSGTIESNLKYGRKDATDEEMRTAAEIAQATEFID
                     SKPEAFKTEISQGGTNVSGGQKQRLSIARAIAKNPEVYIFDDSFSALDLKTDAALRKA
                     LKSKTAESTVLIVAQRISTILNAEQIIVLNEGEIVGIGTHKELLKNCEVYEQIALSQL
                     SKEELANE"
     gene            2824..4656
                     /locus_tag="PC466_003381"
     CDS             2824..4656
                     /locus_tag="PC466_003381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2770733.1"
                     /translation="MSRMGRGPMGKSMEAGQKANDFKGTMRKLIAYLSKFKISIILVI
                     VFAIGSASFSIVGPKILGKATTKIFEGLVSKVSGGNVGIDFNAIGKILTFLLFLYLIS
                     ALFSFIQGFIMSGISQKVSYNLRKEISAKLDRLPMKYFDTKTHGEILSRITNDIDTLN
                     QSLNQSMTQLITSVTTMIGVLIMMLSISGIMTLVAVLILPISMFVISRIIKKSQKYFR
                     YQQEYLGNVNGQVEETYSGQTIVKAFNREDEVIEEFDKLNDSLYNSAWKSQFLSGIMQ
                     PLMMFIGNLGYVMVSILGGWLAIKKTIEVGDIQSFIQYVRNFTQPMTQIAQVANLLQS
                     TAAASERVFEFLEEEEEVQIVENAVSIDGLEGKIDFENVNFGYNPNKTIINDFSVNVK
                     PGQKVAIVGPTGAGKTTIVKLLMRFYDVNSGSILIDGHNIKDFNRSELREMFGMVLQD
                     TWLFSGSIMENIRYGKLNATDEEVIEAAKSAHVHRFIKTLPDGYKMKLNEEASNVSQG
                     QKQLLTIARAILADPKILILDEATSSVDTRTEVLIQKAMDNLMEGRTSFVIAHRLSTI
                     RDADMILVMNEGDIVEQGNHEELLKKGGFYANLYNSQFEEDEAM"
     gene            5375..6652
                     /gene="hflX"
                     /locus_tag="PC466_003382"
     CDS             5375..6652
                     /gene="hflX"
                     /locus_tag="PC466_003382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HDF2770734.1"
                     /translation="MDMTKKGITVGLNINNKSEDFNELMIELENLCSACDIDVVGSIT
                     QNAKQVNRAFYIGTGKVEEILNLIKKENIEIVIFYNELSTSQLKNLEEKLNCEIIDRT
                     ALILDIFAQRAKTREAKLQVEVASLKYMLPRLIGSNENLGRQSGGVGTKNRGSGEKKL
                     ELDRRRIEEKITSLNRELYDLKFQRETQRSMRRKSNLPNVALVGYTNAGKSSIMNKLV
                     DIFKNSEEKKVFEKNMLFATLETSVRNIVLANNKEFLLSDTVGFVSNLPHDLVKAFRS
                     TLEEACEADVLLHVIDISNPSYKSHIKVTEDTLKQIGADGIPMIHVYNKIDLIDVEVL
                     DRILDSIDKEGIFVSVKKDINIDKMIKCICDSIFKDCVRCKFLIPYDKGHVVSYFNEN
                     TSIINTEYREDGAILDVECSNIEYNKYKKYALE"
     gene            6885..7382
                     /locus_tag="PC466_003383"
     CDS             6885..7382
                     /locus_tag="PC466_003383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF2770735.1"
                     /translation="MDAESLMKKYMVDDDSRKQAIFASIFVMQNKLQTTCDKLDPELT
                     MKQWLLLAIADSVDETLTLTKLGELMGCSRQNVKKLAIALEKKGFIQIEQNEKDSRAI
                     CLVTKDRVQEYSKKVRGMQEKVLQLLFEDFTEKEVEQLFFGIMKLSIGIENVKNYVEN
                     NDVGE"
     gene            7432..7956
                     /locus_tag="PC466_003384"
     CDS             7432..7956
                     /locus_tag="PC466_003384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HDF2770736.1"
                     /translation="MKSVVVIYKSKYGSTKKYAKWLSELLSCDIFETKNINIEKVMKY
                     DTIILGGGLYACNIAGISFLKKNYKDLQKKNLVVFGVGAAPYDDEVIKKLREVNFKDE
                     LNKVPCFYCRGAWDETKMSFIDYTLCSFFKKSIAKKERQGLKPAEAPLLSGEAFDWCN
                     KENLTPILNYIRKL"
BASE COUNT         3167 a          825 c         1459 g         2544 t
ORIGIN      
        1 tatagtaaaa taatgcttag ccgactaagt aatataaaaa ataaggaggg caagtatgaa
       61 tagcaattct gaagaaaaat taaatgatgt tttcttgcaa ttaatgcgaa tatattttat
      121 aagaactcat ttttattttg ataaattagg cttatatcat ggtcaacccc aaatactttt
      181 ttctttaaag atgaaagatg ggcaaagtca aaaagaatta gcagataaaa ggaaagtaaa
      241 agcatctaca actacagtta tgataaagag gatggaaaaa gctggacttg tggaaagaaa
      301 acaagatgaa aaggaccaaa gagtatctag gatttttttg acagacaaag gtttagaaat
      361 atgtaataaa gttgaagaat ttaacaagga attggaaaga gagttttttt taggatttag
      421 tgaagaagaa aaaatagtac ttagaagact tctaatgcaa gtacgagata atttaaaagc
      481 aggatgtcat aagcatgaag atgaaaaata tttttaaagt ttaaaataat gtttttcaat
      541 ttaatgttat tagactaatt aatattacag aagggaagaa atgtatgttt aaattaatta
      601 aatatttaaa gaaatcggca ttatcaatag taataatagt ctgtctattg gtaattcaag
      661 cggtatgtga cctttcttta ccagaataca catccaatat agtaaatgta ggtatacaac
      721 aaggtggagt agaaaactct gttccatctg tgattagaga gagtgaatta aataaaatta
      781 ctttatttat ggataaaagt agtaaggata aagtactaga taattatact ttgctgaata
      841 aaaaggatta tgttaagtat aaagataagt acccaggtct aaaagatgaa tctctttatg
      901 agttaaatac taaagacaaa gacactatag atgatttaaa tgttattttt ggtaaagcta
      961 ttttaatagt atcagggctt gagggcgata gtaaagaggt aaaagctatg aaagctcagt
     1021 taatgagtaa acttccacca caagctactc aaagtggaga tgttgatata tttaaattgt
     1081 tatcagcaat gccaaaggaa cagttagata cattgactaa agagatgagc aaaggctttg
     1141 aaagtatgcc agagagtatg ataacacaaa gctctgtttc atatgtaagg tcagaatatg
     1201 agaaaatagg tattgataca gaaaaaactc aaaataatta tatattattt actggtgcta
     1261 aaatgcttgg tatagcaatg attagtatgg tagctacaat aacagtagga tttttagcag
     1321 caagagtagc agcaagtgta ggtagaaatt taagaagtgg agtatttaga aaagttatgt
     1381 cattttcaaa tactgaaatg aatgaatttt ctacagcttc attaattact cgtagtacaa
     1441 atgatattca acagatacaa atgttgatgg ttatgttgct tagaatagta ttctatgcac
     1501 ctataatggc tataggtgga gtgataaagg ttttaaacac aaatacttca atggcctgga
     1561 ttatagcagt agcagtagtt gctatcttat cattaattgt agtgttattc tcagtggtta
     1621 tgcctaagtt taaactggtt caaaagcttg ttgataagtt aaacttagta agccgtgaaa
     1681 taattactgg tattccagtt atcagagctt ttagtactga aaaacatgaa gaagaaagat
     1741 ttgataaagc aaataaaaat ttaactaaaa caaatctttt tgtaaataga gttatgacat
     1801 gtatgatgcc tgctatgatg cttataatga accttatcac agttcttata gtttggagag
     1861 gtgcatacag tgttgattct ggagcaatgc aagttggaga tatgatggca tttatacaat
     1921 atacaatgca aataataatg tcattcttaa tgatatcaat ggtatctatt atgcttccaa
     1981 gagcatccgt ttcagctaca cgtatagatg aagtattagt gtcagatata agcataaaag
     2041 acccagaaaa atcagaggca caagagttta aggaagataa aaagggtctt gttgaattta
     2101 aaaatgtttc gttcatgtat ccagacgcag aagaacctat attaacaaat atatctttta
     2161 cagcaaagcc aggagaaaca actgccttta taggaagtac tggtagtggt aagtcaactc
     2221 ttataaattt aattcctcgt ttctttgatg ttactgaagg agaaatatta cttggtggag
     2281 ttaatataaa aaatgtttct caacatgatt taagggaaaa aattggatat gtacctcaaa
     2341 agggagtatt gttttctggt actatagaat ccaacttaaa atatggtaga aaagacgcaa
     2401 cagatgaaga aatgagaaca gcagctgaaa tagctcaagc tacagaattt atagattcta
     2461 aaccagaagc ttttaaaact gaaatttctc aaggtggaac aaatgtatct ggaggtcaaa
     2521 aacaaagact ttctattgca agagcaatag caaaaaatcc agaagtttat atatttgatg
     2581 atagtttttc agcacttgac ttaaaaactg atgcagctct tcgtaaggct ttaaaatcaa
     2641 aaactgctga aagtacagtt ctaatagttg cacaaagaat tagtactatc ttaaatgcag
     2701 aacagataat tgttttaaat gagggagaaa tagttggaat aggaacacat aaagagcttc
     2761 taaaaaattg cgaagtttat gagcaaatag ctttatcaca actttcaaag gaggagctag
     2821 ctaatgagta gaatgggaag aggtcctatg ggaaaatcta tggaagcagg acaaaaagca
     2881 aatgacttta aagggactat gcgaaaacta attgcatatt tatctaaatt taaaatatca
     2941 ataattttag taattgtatt tgctattggt agtgcatcgt tttctatagt aggtccaaaa
     3001 attttaggaa aggcaactac aaagatattt gaagggttag tgagtaaagt ttctggagga
     3061 aacgtaggta tagattttaa tgcaattgga aaaatcttaa cctttttact tttcctttat
     3121 ttgataagtg cactgttctc ttttatacaa ggatttataa tgagtggaat ttctcaaaaa
     3181 gtatcctata atttaagaaa agagatttca gcaaaattgg atagattacc aatgaagtat
     3241 tttgatacta agacgcatgg tgaaatatta tcgagaatta cgaatgatat agatacttta
     3301 aatcaaagtt taaatcaaag tatgacacag cttataacat cagtaacaac tatgataggt
     3361 gttttgataa tgatgttatc tataagtgga attatgacat tagtggcagt tttaatatta
     3421 ccaatatcaa tgtttgtaat ttcaagaata ataaagaaat cacaaaaata ctttagatat
     3481 caacaagaat atttaggaaa tgtaaatggt caagttgagg aaacttatag tggccaaaca
     3541 atagtgaaag catttaatcg tgaagatgaa gtaattgaag agtttgataa actaaatgat
     3601 agcctgtata attcagcgtg gaaatctcaa tttttatcag gtataatgca accacttatg
     3661 atgtttattg gaaacttggg atatgtaatg gtatcaatct taggaggttg gcttgcaatt
     3721 aagaaaacaa ttgaggttgg tgacatacag tcatttatac aatatgtaag aaactttaca
     3781 cagccaatga ctcagattgc acaggttgcc aatttattgc aatcaacagc agcagcttct
     3841 gaaagagtat ttgagttttt agaagaggaa gaagaagtcc aaattgttga aaatgcagtt
     3901 tcaatagatg gtttagaagg taaaattgat tttgaaaatg tcaactttgg atataaccca
     3961 aacaagacta taataaatga tttctcagta aatgttaaac ctggtcaaaa agttgctatt
     4021 gttggaccta caggagcagg taaaactaca atagttaaac tgttaatgag attttatgat
     4081 gttaatagcg gttcaatact gattgatggt cataatatta aagattttaa tcgtagtgag
     4141 cttagagaaa tgtttggtat ggttcttcaa gatacatggt tatttagtgg ttcaattatg
     4201 gaaaatataa gatatggtaa gttgaatgct acagatgaag aagttataga ggctgctaaa
     4261 tctgcacatg ttcatagatt tattaagacg ttaccagatg gatataagat gaaattaaat
     4321 gaagaagcaa gtaatgtttc tcaaggtcaa aaacaattat tgactatagc tcgtgctatt
     4381 ttagctgatc ctaaaatttt aatattagat gaagctacaa gttctgtcga tactagaaca
     4441 gaagtattga ttcaaaaagc tatggataat cttatggaag gtagaacaag ttttgttata
     4501 gcccacagat tatcaactat acgtgatgct gatatgattc ttgtaatgaa tgaaggagat
     4561 atagttgaac aaggaaatca tgaggaactt ctaaagaaag gcggattcta tgccaatctt
     4621 tacaattctc aatttgaaga agatgaagca atgtaacaaa aaactatctt agcatagaca
     4681 tgtaattaat aagataaaat aaatgagggt gccttaaaat gaacttttta attcataagg
     4741 cactcttttg tgtatgaaat aaagtgtatt tttatcattt taacaatgaa aaagaggatt
     4801 atctatattt tgagatagcc acataatttt atgtctttac aaagtgttta ttttattata
     4861 atatgtagta aggaaaatgt tggaggtgat tatcaaaatg tatatttaat tttattcttt
     4921 aaattttatt ataaatagaa tttaatttta atagttgatg attatattga agtatatgtt
     4981 tttattactt ttattaatca tgcaaataac tacttaaatt taagaatagg gttaaatata
     5041 aaatgataat tacatataag ttaattaaac taatgtattt ttaatatata tttagaattt
     5101 taatccttct tatgatataa gtagcttgtt ttgtattact tagatttgta aggagttttt
     5161 ttattgaaaa aactgcataa tatatttggg aggaggtgta agaaagtgat tttttatata
     5221 agattgagaa aataatgcac gattatggtt attataatag taaataagaa gtgtcattta
     5281 aggataagat aaaaagcaaa attcttgatg aatttaatta tagagccata atctcgtgct
     5341 atagattaaa taaaaaatag cagataagga gaatatggat atgacgaaaa aaggaataac
     5401 agtaggatta aacataaata ataaatctga ggactttaat gaactaatga ttgaacttga
     5461 aaacttatgt tcagcatgtg atattgatgt tgtagggagt ataactcaaa atgcaaagca
     5521 ggttaataga gcattttaca ttgggacagg taaagttgag gaaatattaa acttaataaa
     5581 gaaagaaaac atagagatag ttatatttta caatgaactt tctacatcac aactaaaaaa
     5641 tcttgaagaa aagcttaatt gtgaaattat agatagaacg gcattgatac ttgatatatt
     5701 tgcacaaagg gcaaaaacta gagaagctaa acttcaagta gaagtagcaa gtttaaaata
     5761 tatgttacca agacttatag gttcaaatga aaatttagga cgtcaaagtg gtggagttgg
     5821 tactaaaaat agaggttctg gtgagaaaaa attagaactt gaccgtagaa gaatagaaga
     5881 aaagataaca tctttaaata gggagttgta tgatttaaaa ttccaaagag aaactcaaag
     5941 aagtatgaga agaaaatcaa atcttccaaa tgtagctcta gtcgggtata caaatgctgg
     6001 taaatcttca ataatgaata aactagtaga tatatttaaa aactctgaag aaaagaaagt
     6061 gtttgagaaa aacatgttat ttgctacact tgaaacttct gtcagaaata tagttcttgc
     6121 aaataacaaa gaatttttat tatctgatac tgttggtttt gtaagtaatc taccacatga
     6181 cttagtaaaa gcatttaggt caacattaga agaagcatgt gaggcagacg tactgttaca
     6241 tgttattgat atttcaaatc caagctataa aagtcatatt aaagtgacag aagatacttt
     6301 aaaacaaata ggtgcagatg gtatacctat gatacatgtg tataataaaa ttgatttaat
     6361 agatgtagaa gtattggata gaattttaga tagtatcgat aaagaaggta tatttgtttc
     6421 agttaaaaaa gatataaata tagataaaat gataaaatgt atttgtgata gcatatttaa
     6481 agattgtgta agatgtaagt tcttaattcc atatgataaa ggtcatgtag tttcttattt
     6541 taacgaaaat acgagcatta taaatacaga atacagagaa gatggagcta ttttagatgt
     6601 agaatgtagc aatatagaat ataataagta taaaaagtat gctttagagt aaattttgaa
     6661 aaacttatta tagcctaaaa tatatttaat ttataattta ttataaattg attgtaaata
     6721 tgattttatg aaacggtata gccataatgc tatgccgttt tgccatttat aataaaaata
     6781 aatttattga cacaatagta actaattact ataatataaa gtaactagtt actatttaaa
     6841 attatcaaaa aattaaaatc taagataaag agaagtgtat aataatggat gcagaaagtt
     6901 taatgaaaaa atatatggta gatgatgata gtagaaaaca agctatattt gcaagtatat
     6961 ttgtaatgca aaataaactt caaactacat gtgataaatt agacccagaa ttaacaatga
     7021 aacaatggtt acttttagct attgcggact ctgtagatga aactcttaca ttaaccaaac
     7081 ttggagaatt aatggggtgc tcaagacaaa atgtaaaaaa actagctatt gctttagaaa
     7141 agaaaggttt tatacaaatt gagcaaaatg aaaaagattc aagagctatc tgtcttgtga
     7201 caaaagatag agtgcaagag tattctaaaa aagtaagagg tatgcaggaa aaagtattac
     7261 agcttttatt tgaagatttt acagagaaag aagtggaaca gttatttttt ggaattatga
     7321 aattaagtat aggaattgaa aatgtgaaaa attatgtaga aaataatgac gttggagaat
     7381 aagcaagtat caaatcaact ttgtatgaca tcagagaggg gggtaattta tatgaaaagt
     7441 gtagtagtga tttataagag taagtatggt tcaacaaaaa aatatgctaa atggctttca
     7501 gaattattgt cttgtgatat ttttgaaact aagaatatta atatagaaaa ggttatgaag
     7561 tatgatacga ttattttagg aggaggtctt tatgcttgta atatagcggg aatttctttc
     7621 ttaaaaaaaa attataaaga tttgcagaaa aaaaatttag tagtatttgg cgtaggagct
     7681 gctccatatg atgatgaagt aataaagaaa ttaagagaag taaactttaa ggatgaatta
     7741 aacaaagttc cttgctttta ttgtcgtggg gcatgggatg agacaaaaat gtcttttata
     7801 gattatactc tttgtagttt ttttaaaaaa tctatagcta aaaaagaacg tcaaggtctt
     7861 aaaccagcag aagcaccttt attgtctgga gaagcctttg attggtgtaa taaagaaaat
     7921 ttaactccaa tacttaatta tataagaaaa ctttaagagg tatatattta taattattta
     7981 ttatctaaag ttaga
//
LOCUS       DAMJYN010000129         7881 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.135, whole genome shotgun sequence.
ACCESSION   DAMJYN010000129 DAMJYN010000000
VERSION     DAMJYN010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7881)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7881)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7881
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.135"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     misc_binding    109..320
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            483..1772
                     /locus_tag="PC466_003385"
     CDS             483..1772
                     /locus_tag="PC466_003385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosine permease"
                     /protein_id="HDF2770737.1"
                     /translation="MEEEKINYALEQIPENQKRGWVAMFSVLVAIGVDLSSVILGAEL
                     AQSMPMKQAILSVIVGSFFSAILYTTCSLVGSSTSLSTSMITKYVFGEAGAKIFSLVI
                     GVSLLGWFGVQVGFFAQNAQIIIKDIFNLDVSMQILSLIGGLLMMSTAIYGYKAMEKL
                     SVYSVPFLLVLMMLTIFLAFRANGISVDDNMKSTMTFAGGVSLSMSIIIVGAIVSPDI
                     SRWAKSRRDCALSSFLGIQFGNAFMIIVSIVLVKCMGTSDIMRIFITLGIAIPGIIVL
                     TLAQWTTNTSNVYSASLSIALVLKKAPEKVLTIVLGIIATLLAVFGIYEGFIGFLNLL
                     GIVIAPVGGVYTAEYYIVKQELKGFDKGVLYKPIVKRSIVSWIIGILITYLSTYGFIT
                     LTTIAPLDGFIAGFVVQSIIGKVLCSTKNKQEIDKAV"
     gene            1826..2905
                     /locus_tag="PC466_003386"
     CDS             1826..2905
                     /locus_tag="PC466_003386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF917 domain-containing protein"
                     /protein_id="HDF2770738.1"
                     /translation="MRFLTEESVDKIAVGAAVLGTGGGGDPYVGKLVAKQAIKKYGPV
                     KVISLDELDDDALVVPVSGMGSPVITIEKLLSEVELTTPLEIMEKLLNRKVDVIIPIE
                     IGGINSLMPIAVAAKKGLPILDADSMGRAFPEAQMVTFYLEGYEASPAVMSDEKGNSA
                     ILYPVDGIWSERLARTLTVEMGGSSSISDYNLSGAQVKKAAIGNTLTIAETIGGFLLE
                     NKSDSKGAVENILKELCGYKLFEGKVIDIKRELKGGFTRGHAFFAGINEYDGEYSILF
                     QNENLIAKKGDTPLCITPDLIAVLDLETGFPITTERIKYGSRVMVVAFPCNEKWRTEK
                     GIETVGPGYFGYDVEYKTVEELQGK"
     gene            2926..4470
                     /locus_tag="PC466_003387"
     CDS             2926..4470
                     /locus_tag="PC466_003387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020246462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HDF2770739.1"
                     /translation="MYRVGIDVGGTNTDACILDGELKVIHSVKVATTKDVETGVYNAL
                     KKVIDESKIDHSLIKYAMLGTTHCTNAIVERKRLNNVAMIRIGKPATTAILPFIDWPE
                     DLREKIELDSILVSGGYEFDGRKINELCKDEVVEFCNRIKGKVESVAISGVFAPVNKQ
                     QEEEVAKWVREILGDIPISLSNEIGNIGILERENGAILNSALSQVGKAVSLGFEKALK
                     DLGIDAQIYFSQNDGTLMNLEYTMKYPIFTIGCGITNSIRGASFLSKVKNAIVLDVGG
                     TTSDLGVLYNGFPRESSIPVTIGGVHTNFRMPDVLTIGLAGGTCVKGEKDNIKIGPES
                     VGYRITEDAIIFGGDTLTLSDVVTKLDMAFEDRKSNVENLDKEYCNEVYKKVILKLED
                     AVDQMKTSQDDVELVLTGGGSIIVPEKLKGISNVIRPPHYTAANAIGAALGQISGDVE
                     KVYSLDKMSREDAIEDAKKEAVNKALKAGAKEDTIEVLNIEDVPLAYLPGNALLIKVK
                     VVGDLI"
     gene            complement(4633..5175)
                     /locus_tag="PC466_003388"
     CDS             complement(4633..5175)
                     /locus_tag="PC466_003388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HDF2770740.1"
                     /translation="MKSYIALLRGINISGKNKIIMSELKASFVELGYSEVSTYLNSGN
                     VVFLSDVDDNKVISNTIRLMIKKQFELEIPVFIISQEELKDILNNAPNWWGDNNKEIY
                     DNLIFMFPDLSYDEFYDEVGNPKEEYEKVYHYKNAIFWSFSRKDYKKTNWWSKTASSN
                     VSDKITIRTANTVRKIVGMR"
     gene            complement(5323..5607)
                     /locus_tag="PC466_003389"
     CDS             complement(5323..5607)
                     /locus_tag="PC466_003389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDF2770741.1"
                     /translation="MAKNTKQTTVHIDETLLKEVKRIGINENKSISQIINESIIDYIL
                     VYRENEDKEKNEHDKNLNETINEFKKEEEKRMQAKSAARAIAEAKKRVLY"
     gene            complement(5670..6434)
                     /locus_tag="PC466_003390"
     CDS             complement(5670..6434)
                     /locus_tag="PC466_003390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HDF2770742.1"
                     /translation="MNNYLKFATYQLIGFTSSIPSLIKIKKNPDKFSLKEKFEFMQKQ
                     AKKSLDIVNIELNIIGKETLPKEPLLFVVNHSSMLDSFILTASVERPIGCVIADEPVW
                     RNIPIFKEWAKLLRCVYVNRKNNREGIKSIAQASQNILTGQSMAVFPEGDLTWIKEPN
                     SLVSEFRSGALKIAYKAKCPIVPLVIKNSKDTYEGYQPIGKINSVPVEVEFLEPIYDH
                     IENPRLKSSVLGENIKNKMINTIENFRKSNKTFKEF"
     gene            complement(6716..6982)
                     /locus_tag="PC466_003391"
     CDS             complement(6716..6982)
                     /locus_tag="PC466_003391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HDF2770743.1"
                     /translation="MIESRCGILCYECGYKEKVNCKGCTDIEKPFWGEQCPVKSCCED
                     KNLIHCGLCDTFPCEMLNQFAYDKEQGDDGKRISQCKKWAVLAL"
     gene            complement(7025..7834)
                     /locus_tag="PC466_003392"
     CDS             complement(7025..7834)
                     /locus_tag="PC466_003392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2770744.1"
                     /translation="MNKIINNILNTCKQYTYILPHKLLRQYIAHYTISIPDTSIKEKL
                     TLIPDASGCMIFKFDKKGIESAFWGATTKTTIVKNDIENVLFRVFVEFRPGGVYYLTG
                     LSQRESTDLKISLEDFNTLFSLEVNSIFERTSTIKELVEQLDMLFLSYLLKSNIVDMT
                     IPILENARKQNSIMSVKNISQISCYSERHLNRIFNNSLGMSVKSYLRLLRINLVLQEV
                     QNNKRPFATLAQDIGYYDQSHFINDFKSICGVNPTTYIKNLSDFYNEKYKF"
BASE COUNT         2743 a         1001 c         1288 g         2849 t
ORIGIN      
        1 gaaaatttac atataaaact aaaaaatgta agtaattgac tttttaagtt gacaaaatat
       61 tgcatatata ttatgatata aatcataaat taactacaaa tcaatattat atattcgtag
      121 aagaagaaag tagcataaag gaattttaca gagagttaga tttggctgag aactaatatt
      181 ggaatttatg tgaaaaggac tttggagaat actattgtaa ttatgttaga atagtggttt
      241 aattcgcctt aagaaaatga gtgagtaaaa ttaattttta ctaataagag tggtaacacg
      301 gatttatatt cgtctcttgg atttttccaa gaggcgtttt ttattataaa cttatttcag
      361 aaaatttaaa actatatatt aaatgaaaat tataaaaata tgatagttaa taaatttata
      421 aattagaaaa ttgtaaaata tgctaaggtc agtagtttta cgatttaaat ggagggatga
      481 aaatggaaga agaaaaaatt aactatgctc tggaacagat tccagagaat caaaaacgtg
      541 gttgggtagc tatgttttca gttttagtag caataggtgt ggatttatca tctgttattt
      601 taggcgctga gttggcacag agtatgccaa tgaaacaagc aatattgtca gtaattgttg
      661 gttcattttt ttctgcaatt ttgtatacta catgctcttt ggttggttca tctacaagtt
      721 tatctacatc tatgataaca aagtatgtat ttggagaagc tggagcaaaa atattttctc
      781 tagttatagg ggtttctcta ttaggttggt ttggagttca agtaggtttc tttgcacaaa
      841 atgcacagat aataataaaa gatatattta atttagatgt cagtatgcag attttaagcc
      901 taataggtgg tctcttgatg atgagtactg caatttatgg atataaggcc atggagaagt
      961 tgagtgtgta ttcagtacca tttttattag ttcttatgat gctaactata ttcttagctt
     1021 ttagagcaaa tggaatttca gttgatgata atatgaaatc tactatgaca tttgcaggtg
     1081 gagtttctct gtcaatgagt ataataatag ttggtgcaat tgtatctcct gatataagtc
     1141 gttgggctaa aagtagaaga gactgtgctc tttcaagctt tttgggaata caatttggaa
     1201 atgcttttat gataatagtt tcgatagtat tagtaaaatg tatgggaact tcagatatta
     1261 tgagaatttt tattacatta ggaattgcta taccaggtat aatagtactt acattagcac
     1321 aatggactac aaatacaagt aatgtatatt cagcatcatt aagtatagct cttgtactta
     1381 agaaggctcc tgagaaagta ttaactatag tccttggtat tatagcaaca ttattggctg
     1441 tatttggaat atatgaaggt tttataggat ttttaaattt acttggaatt gtaattgcac
     1501 ctgttggtgg tgtatataca gcagaatatt acatagtaaa gcaagaactt aaaggctttg
     1561 ataaaggagt attatataaa ccaatagtta aacgttcaat agtgtcttgg ataattggta
     1621 tattaataac ttacctttca acatatggat ttataactct tactactata gcacctttag
     1681 atggttttat agcagggttt gtagtacaat ctattattgg aaaagtgctt tgttcaacaa
     1741 aaaataagca agaaatagac aaagcagtat aaagaaattt gtttataaag tataaaataa
     1801 attagaaata tgaggagaaa gtaacatgag atttttaaca gaagaaagtg tagataaaat
     1861 agcagttggt gcagcagtgc ttggaactgg aggtggaggt gacccatatg taggtaaatt
     1921 ggttgcaaaa caagccatta aaaagtatgg tcctgtaaaa gtaataagtt tagatgaact
     1981 tgatgatgat gctttggtag ttccagtatc tggtatgggt tctcctgtaa ttacaataga
     2041 aaaattactt tcagaagtag agttaactac ccctttagaa ataatggaga aattattaaa
     2101 tagaaaagtg gatgttataa ttcctataga aataggaggg ataaactcac ttatgcctat
     2161 agcagttgct gctaaaaaag gacttcctat cttagatgca gattctatgg gtagagcttt
     2221 ccctgaagct caaatggtaa ctttttatct tgaaggatat gaggcatctc ctgccgtaat
     2281 gtctgatgaa aaaggtaatt ctgccatcct ttatcctgtg gatggaattt ggtcagaaag
     2341 attagctaga actttaactg tagaaatggg aggaagttct tctattagtg actataattt
     2401 aagtggagct caagttaaaa aagctgctat aggtaatact cttacaatag ctgaaactat
     2461 aggagggttt ttacttgaaa ataaatctga ttcaaaaggt gctgttgaga atatactaaa
     2521 agaattgtgt ggatacaagt tatttgaagg aaaagtaatt gatattaaga gagagttgaa
     2581 aggtggattt actagaggac atgccttttt tgctgggatt aatgagtatg atggagagta
     2641 ttctatatta ttccaaaatg agaatttaat tgccaaaaaa ggtgatacac cactttgtat
     2701 tacaccagat ttaatagcag tattagattt agaaactgga tttccaataa ctacagagag
     2761 aataaaatat ggctctcgtg ttatggtagt agcttttcct tgtaatgaaa agtggagaac
     2821 agaaaaagga attgagacag ttggacctgg atactttgga tatgatgtgg aatataaaac
     2881 agtagaagaa ttacaaggaa aataaaagtt taggaggaaa ttttgatgta tcgtgtagga
     2941 attgacgttg gaggaacaaa tacagatgct tgtatactgg atggggaatt aaaagtaatt
     3001 cattcagtta aggtggcaac tacaaaagat gttgaaactg gtgtttacaa tgccttaaaa
     3061 aaagttatag atgaaagtaa gattgaccat tcattaataa aatatgctat gcttggtaca
     3121 actcattgta caaatgctat tgtagaaaga aaaagactta ataatgtagc tatgataaga
     3181 ataggaaagc cggccactac tgccattctt ccatttatag attggccaga agacttaaga
     3241 gaaaaaatag aattagattc aatattggta tctggtggat atgagtttga tggtagaaag
     3301 ataaatgaac tttgtaaaga tgaagttgta gagttttgca atagaataaa aggcaaagtg
     3361 gaaagtgttg caataagtgg agtatttgct ccagtaaata aacaacaaga agaagaagtt
     3421 gcaaaatggg ttagagaaat tttaggggat attcctatat ctttatcaaa tgaaataggt
     3481 aatataggta tattagaaag agaaaatgga gctattttaa attctgcatt gtctcaagta
     3541 ggtaaagctg tatctttagg atttgaaaaa gcacttaaag acttaggtat agatgctcaa
     3601 atatatttca gtcaaaatga tggaacatta atgaatttag agtatacaat gaaataccca
     3661 atttttacaa ttggatgtgg aataacaaat tctataagag gagcttcctt cttatcaaaa
     3721 gtaaaaaatg caatagtatt agatgttggt ggaactacaa gcgacttggg tgtactatat
     3781 aatggattcc ctagagaatc atctattcca gttacaattg gaggagtaca tacaaacttt
     3841 agaatgccag atgttttaac tattggtctt gctggtggta catgtgtaaa aggcgaaaaa
     3901 gataatataa agataggtcc tgaaagtgtg ggatatagaa taactgaaga tgcaataata
     3961 tttggtggag acactctaac tttatcagat gttgttacaa aattagatat ggcgtttgaa
     4021 gatagaaaaa gcaatgttga aaacttagat aaagagtatt gtaatgaggt atataagaag
     4081 gttattttaa aattagaaga tgctgtagac caaatgaaga ctagtcaaga tgatgttgaa
     4141 ttggttttaa ctggtggagg aagtataatt gttcctgaaa aactaaaagg cataagcaat
     4201 gttataagac ctcctcatta tactgctgca aatgctattg gtgcagcttt aggacaaata
     4261 agtggagatg tagaaaaagt atacagttta gataaaatgt cgagagaaga tgccatagaa
     4321 gatgcaaaaa aagaggctgt aaataaagct ctaaaagctg gtgctaaaga agatactata
     4381 gaagtattaa atatagaaga tgttccactt gcataccttc ctggtaatgc acttcttata
     4441 aaagtaaaag ttgttggtga tttaatttaa agaataaata taagtatttc cagaattata
     4501 taaatatttc tggactcatt tttaaactta ttttatcaat aaaaacagca taacttttga
     4561 ctatattctt ataagtttcc gaacagccga tatataccta ttttttgagg tttatcggct
     4621 gtttgttatc ttttatcgca ttccaactat ttttcttacc gtatttgctg tacgaattgt
     4681 aatcttatca cttacatttg aactggcagt ctttgaccac caatttgtct ttttataatc
     4741 tttacgacta aaagaccaaa agatagcatt tttataatga tatacttttt catactcttc
     4801 tttaggattt ccaacctcat cataaaactc gtcataagat aagtcaggaa acataaaaat
     4861 aagattatca tatatttctt tgttgttatc tccccaccaa ttaggagcat tatttagtat
     4921 atcttttaac tcctcttgtg aaataataaa aactggtatt tccaattcaa actgtttttt
     4981 tatcattaat cttattgtat ttgagataac cttgttgtca tctacatcac ttaaaaagac
     5041 aacattacca ctattaaggt atgtagaaac ttctgaataa ccaagttcta caaagcttgc
     5101 ttttaattca gacataatta tcttgttctt accacttata ttgatacctc ttaataatgc
     5161 gatataactt ttcatataat aagttcacct ctaaacattc acatttttct atgtagtaca
     5221 aactggaatt tgcatctttt ataattcttt caaaacttct tcatatgtaa tttttttaat
     5281 ataaaaaaat cggtgcttaa tttgtaccga tttttatttt tcttagtaaa gaactcgttt
     5341 ttttgcttct gctatagctc tagcagcact ttttgcttgc attctttttt cttcttcttt
     5401 tttaaattca tttattgttt catttagatt cttatcatgt tcattttttt ctttatcttc
     5461 gttttctctg tatactaata tataatctat tattgattcg tttattatct gagatatact
     5521 tttattttca ttaattccta ttctcttaac ttccttaagt agagtctcat caatatgaac
     5581 cgttgtttgc tttgtatttt ttgccacctt aatcacctct taaaaaaaat tctaacatta
     5641 aaattttttt tagtcaataa attttaatat taaaattctt taaatgtttt atttgatttt
     5701 ctaaaatttt ctattgtatt tatcatctta ttttttatat tttcacctag tacagaagac
     5761 tttagtctag gattttctat atggtcataa attggttcta aaaattcgac ttcgacagga
     5821 acagagttaa ttttaccaat aggttggtat ccttcataag tatcttttga attttttatt
     5881 acgagtggaa caatagggca ttttgcttta tatgctatct ttaaagctcc acttctaaac
     5941 tccgaaacca atgaatttgg ttctttaatc catgttaaat ctccttctgg aaacactgcc
     6001 atactttgac ctgtaagtat attttgagag gcttgggcta tactctttat accctcacga
     6061 ttgttttttc tgtttacata tacacatctt agtaattttg cccattcttt aaatataggt
     6121 atatttctcc aaactggttc atctgcaatt acacatccaa ttggtctttc tacacttgct
     6181 gttagtatga agctgtcaag catactagaa tgatttacaa caaatagaag tggttctttt
     6241 ggcagtgttt ccttaccaat tatattaagc tctatgttca ctatatctaa agatttttta
     6301 gcttgttttt gcataaattc aaatttttcc tttaagctaa atttatcagg attcttttta
     6361 attttaataa ggctaggtat agaagatgta aaacctataa gttgatatgt agcaaatttt
     6421 aagtaattat tcataaaatt atctccttaa aataaaatta tttattactg taaagatttt
     6481 aacataaaat aaaatttaag tctattttaa ttcaattttg taacatatat tttaaataga
     6541 cagagattga gattttatat ttctaatttt agtaatcaga ttttatcaat aaattactat
     6601 tctattaatt taattaaata acctttaaat ttaattataa aaactgttgc agaaatttct
     6661 acaacagttt aaaaaattta ccttacaaaa acttatttta taacaagaga gtatattata
     6721 aggctagtac agcccatttt ttgcactgag aaattctttt gccatcatca ccttgttctt
     6781 tgtcatatgc aaattgatta agcatttcac atggaaatgt atcacataga ccacaatgta
     6841 taaggttttt atcttcacaa caagatttta caggacattg ttcaccccaa aatggtttct
     6901 caatatctgt acaaccttta caattgactt tttccttgta tccacattca taacataaaa
     6961 ttccacatct tgattctatc attttaagtc actccttaaa tataaatttt attatgattg
     7021 tatatcaaaa tttatacttt tcattgtaaa aatcggacaa attttttata taggttgttg
     7081 gattaacacc acaaatagat ttaaaatcat ttataaaatg agattggtcg taataaccaa
     7141 tatcttgtgc taaagttgca aatggtcttt tattgttttg tacttcttgt aatacaaggt
     7201 ttatacgaag taatctaagg tatgatttaa cactcatccc aagagaatta ttaaaaattc
     7261 tatttaaatg tcgttcacta taacaactaa tttgtgaaat gtttttaaca gacataatag
     7321 agttctgttt tctagcattt tcaagaattg gtatagtcat atctactata tttgatttca
     7381 ataagtatga taagaataac atatctaatt gttctactaa ttcctttata gtacttgttc
     7441 tttcaaaaat ggaattaacc tctaagctaa ataatgtgtt aaaatcttca agtgaaattt
     7501 ttaaatctgt agattctctt tgagaaagac ctgtcaaata atatactcca cctgggcgaa
     7561 actcaacgaa tactctaaaa agtacatttt ctatatcatt ttttacaata gtagtttttg
     7621 ttgtggctcc ccagaatgcg ctttctatac cttttttgtc aaatttaaat atcatacatc
     7681 cactagcatc aggtattaat gtaagctttt ctttaatact tgtatctgga atagatattg
     7741 tatagtgtgc tatatactgt cttaacaatt tatgtggcaa aatatatgta tactgtttgc
     7801 aggtatttaa aatgttattg attattttat tcataagtat atcctcctga tatataaaaa
     7861 ataagtatac taatttattt t
//
LOCUS       DAMJYN010000130         7794 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.136, whole genome shotgun sequence.
ACCESSION   DAMJYN010000130 DAMJYN010000000
VERSION     DAMJYN010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7794)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7794)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7794
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.136"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(187..942)
                     /locus_tag="PC466_003393"
     CDS             complement(187..942)
                     /locus_tag="PC466_003393"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HDF2770745.1"
                     /translation="MLKVIINGYNGTMGRVLAECVKKDNELELVCGVARSADEKGHHS
                     DTKLYKTMTDVTEKTDVIIDFSHHETLEPILSYALKNNTPVVLATTGYDENDLNKIEE
                     ASKNIPILLSSNTSLGVNILIKLVKDASKMLEGFDIEIIEKHHNRKEDAPSGTATMIA
                     NAIREVLPESENTHGRYGRDCKRKPNEIGIHSIRGGNIISDHDVIFAGDNEVLTLSHH
                     SQSDEVFANGSIVAAKFLIGKQSGLYKMSDILG"
     gene            1383..2372
                     /locus_tag="PC466_003394"
     CDS             1383..2372
                     /locus_tag="PC466_003394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HDF2770746.1"
                     /translation="MLKEEKTYQEKDAKVFNGVAALIMIVLFLVVSIGIMVFGIVKLD
                     SGFTGIGSLMLILGLVFIVVDFILFFGLKMINPKEAIVLVLFGNYYGTIKKEGYYWVN
                     PFCSAINPAVSRINVSKSSSDEKVDISTNSRGKKVSLKTMTLNNEKQKVNDLLGNPII
                     IGVVVIWKVINATKAVFNVDNYNTFLSIQCDSTIRNVSRLYPYDVSEDGDEKSLRGSS
                     QEIADRLKDELQSRVDIAGIEVCEVRITHLSYAPEIAAAMLQRQQAEAIIAARKKIVE
                     GAVSMVEMALTNLSENNVVTLDEERKAAMVSNLLVVLCGNKDAQPVVNSSSIY"
     gene            complement(2643..3359)
                     /gene="dapD"
                     /locus_tag="PC466_003395"
     CDS             complement(2643..3359)
                     /gene="dapD"
                     /locus_tag="PC466_003395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HDF2770747.1"
                     /translation="MVNLNDAYEIARYIKEVKKKTPVKVYVNTNSLHFQSTDKFKVFG
                     SNGSYIFVGDYEDIMEVLDKHGNDITDTHVEYDRRNSAIPLKNTLNEHARIEPGAIIR
                     DMVTIEKNAVVMMGAVINIGAVIGEGSMVDMNAVIGARGTLGKNVHLGAGAVVAGVLE
                     PPSATPVIVEDDVLIGANAVILEGVRIGKGAVVAAGAVVTTDVEAGAVVAGSPAKVIK
                     MKDEKTADKTKLMEDLRNLD"
     gene            complement(3583..4332)
                     /locus_tag="PC466_003396"
     CDS             complement(3583..4332)
                     /locus_tag="PC466_003396"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HDF2770748.1"
                     /translation="MLKVIATGYDGKMGKILADTIREDNELELVCVAARGLDSYEGDL
                     KIYEDMSTIVEEADVVIDFSHHSNLDNILSYVLKTKTPLVIATTGYNDNEMNKIREAA
                     KVIPVFQSYNMSLGVNVLVKLVKDAAKLLEGFDIEIIEKHHNRKVDAPSGTAVMIANA
                     IKEVLPNVENNYGRYGRSAKRQPNEVGIHAIRGGNIVGEHDALFAGDNEVLTISHQAQ
                     SRGIFASGSIAAAKYLVKQKPGFYNMDSMLG"
     gene            complement(4399..5286)
                     /locus_tag="PC466_003397"
     CDS             complement(4399..5286)
                     /locus_tag="PC466_003397"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HDF2770749.1"
                     /translation="MIFKGSAVALVTPFTKDNKVDFDKLGELVEYQIANGTDAIVSCG
                     TTGEANTMTDEEQLATIKYVVEKVNKRVPVIAGSGSNDTMHSVNLSQEAEKLGVDALL
                     IITPYYNKANKAGLKRHFETIANSVKLPIILYNVPGRTCVNISPSLIVELAKIDNIVA
                     VKEASGDLGQVAEIASLVPDDFAIYSGNDDTILPLLSLGGQGVISVLANVCPQETHDL
                     VAKFFEGDIEGSRKLQLGMDALIAALFIEVNPIPVKTAMNLLGFNVGDLRLPLAEMDP
                     ANLEVLKKELVNFGLKVNA"
     gene            complement(5403..6404)
                     /locus_tag="PC466_003398"
     CDS             complement(5403..6404)
                     /locus_tag="PC466_003398"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HDF2770750.1"
                     /translation="MKKVNVAIVGATGMVGRTFLKVLEERNFPIENLFLFSSSKSAGS
                     KVMFCGKEYIVEELKETSFTDRGIQIALFSAGGSISEKYAPIAASNGILVVDNSSQWR
                     MNPDVPLVVPEVNPEAIKNHKGIIANPNCSTIQAMVPLKALDDKYKIKRVVYSTYQAV
                     SGSGVKGVEDLEKGMNGNPTGFYPHQISYNCLPHIDSFTENGYTKEEMKMVNETMKIL
                     DNYDLKITATTVRVPVKNGHSESINVEFNNPFELDDLVKTLEEAPGVVVVDNPAKNEY
                     PTAVEFDDRDEVFVGRIRRDFSVDNGVNLWVVADNIRKGAATNAIQIAEMALSYDLV"
     gene            complement(6829..7710)
                     /locus_tag="PC466_003399"
     CDS             complement(6829..7710)
                     /locus_tag="PC466_003399"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HDF2770751.1"
                     /translation="MLFKGSAVALVTPFTEDNNVNFEKLGELIEYHIENGTDALVVCG
                     TTGEATTMSESEIFAVIKYTVEKVNKRIPVIAGTGSNNTMLSVHMSQEAEKLGVDGLL
                     IITPYYNKTNEKGLKLHFETIANSVKLPIILYNVPGRTKVNIKPSVVAELAKIDNIVA
                     VKEASGDLAQVAEIAKLVPKDFAIYSGNDDTILPLLSLGGSGVISVLANICPKETHDL
                     VTKFFEGDIEGSKKLQLDMDALIAALFIEVNPVPVKTAMNILGFNVGDLRLPLAEMEE
                     TNLNVLKQELTNFGFKF"
BASE COUNT         2654 a         1278 c         1014 g         2848 t
ORIGIN      
        1 gactataaaa taataaacaa tataattcca tataccaata aataagataa tctttaagaa
       61 aaatgattat atttaaaagg taagcataaa atttataaac ttttagaata gaaatctcaa
      121 tcaattagat attcaaattg atgaatatga atacctaaat agattgagat ttattatgta
      181 caaaacttat cctagtatat ctgacatttt ataaagtcca gattgcttac caattaaaaa
      241 tttagctgca actatagaac cgtttgcaaa tacttcatca gattgagaat gatggcttaa
      301 tgtaagaact tcattatcac ctgcaaatat gacatcatgg tcgctgatta tattgccacc
      361 tcttatagag tgtattccaa tttcatttgg ttttctttta caatctctac catatctacc
      421 atgtgtattt tcactttcag gcaagacttc tctaattgca ttagctatca tagtagcagt
      481 tccactaggg gcgtcttctt ttctattgtg atgtttttct atgatttcaa tatcaaaacc
      541 ttctaacatc tttgaagcat ccttaactaa ttttattaat atattcactc caagagatgt
      601 atttgatgat aataatatag gaatgttttt tgatgcttct tctattttat ttaagtcatt
      661 ttcatcatat ccagtagtag ctaatactac aggtgtatta ttttttagag catatgacaa
      721 tattggctct aaagtctcat gatgtgaaaa gtctattatg acatcagttt tttcagttac
      781 atcagtcatt gttttgtaaa gctttgtatc actatgatga cctttttcat cagcagacct
      841 agctacacca caaaccaact ctaattcatt atcttttttt acacattctg ctaaaactct
      901 tcccattgtt ccattatagc cattaattat aactttcaat ataaattcct cctatgaaat
      961 taataaaaat ttgttatatt tctataagtt tattttatca ctaatattat ttatataaaa
     1021 taatattagt gataataagc ttacaattta tcttacatta aaaaaattta agtggatttt
     1081 tcaaaatata gataaacttc tttttcattg tataaatgat aaaaatatat ttgacttcat
     1141 atcaaaaaga gtgccccatg aactaaaaag ttaattttga gataccatat tcatatatca
     1201 tatgatttat ttggaaatca atattaatac attaaaataa ctaaatacat gtatgcataa
     1261 agatgtataa aaaatatata aacatatagt attaatttta aattcaacaa tttaattgtt
     1321 aaaagtgtta ttattaaatt agaaatatct taacttaata tactgagatg ggagtgatag
     1381 atatgttaaa agaagaaaaa acttatcaag agaaagacgc aaaagtattc aatggagtgg
     1441 cagctttgat aatgattgta ttatttttag tagtttcaat aggtatcatg gtttttggga
     1501 tagtaaaact tgatagtgga tttactggaa taggttcact tatgttaatt ttgggacttg
     1561 tatttatagt agtagatttt atcctatttt ttgggctaaa aatgattaat cctaaagaag
     1621 ctatagttct agttttgttt ggtaactatt atggaactat aaaaaaagaa gggtactatt
     1681 gggtgaatcc attttgttca gcaataaacc cagcagtatc aagaattaat gtatcgaaat
     1741 cttcatctga tgaaaaggta gatatatcaa ctaattcaag gggcaaaaaa gtatctttaa
     1801 aaacaatgac tcttaataat gaaaagcaga aagtcaatga tttattggga aatccaatta
     1861 taataggagt ggttgtaatt tggaaggtta taaatgcaac aaaggcagta tttaatgtgg
     1921 ataattataa tacattctta tctattcagt gtgattctac tattcgtaat gtttcaagac
     1981 tttatccata tgatgtatct gaagatggag atgaaaaatc tcttcgtggt agtagtcagg
     2041 aaatagcaga tagattaaaa gatgaattac aatcaagggt tgacattgca ggaattgaag
     2101 tgtgtgaagt gagaattact catctttctt atgcaccaga gattgcagca gcaatgttac
     2161 aacgtcaaca agcagaggct ataatagcag cacgtaaaaa gattgttgag ggggctgtaa
     2221 gtatggtaga gatggcattg actaatttaa gtgaaaataa tgttgtgact ttggacgaag
     2281 aacgtaaagc agctatggta agtaatctgt tagttgtgct ttgtggcaat aaagatgcac
     2341 aaccagtagt aaacagcagt tctatttatt aaattataaa aagtttaata gtttattaca
     2401 ttgatatatt gaaaaattga aggaaataaa aatacttgtc atcaagaaat aaaaatgata
     2461 taagaatgaa taagagaatt gtaaaaaaat aaaatgatta taaataaaag ataaaaatat
     2521 tataaaaaag agggtgcctc tgatgaatta aattcataca gagacacctt tttaattaat
     2581 tttttaaatt agtatattat tgtttaatta atctttctaa ttaataatat agtactattt
     2641 aattagtcta aatttctaag gtcttccata agcttagttt tgtcagccgt tttttcatct
     2701 ttcattttta taactttagc aggagaacca gcaacaacgg caccagcttc tacatcagta
     2761 gttacaacag caccagctgc aacaacagca cctttaccga ttctaacacc ttcaagaata
     2821 actgcattag ctcctattaa aacatcatct tcaactataa caggagtagc agaaggtggc
     2881 tctaaaacac cagcaacaac agcaccagca cctaagtgaa catttttacc aagagttcct
     2941 ctagctccaa taacagcatt catatctacc atagaacctt caccaataac agctcctata
     3001 tttataacag ctcccatcat tacaacagca tttttttcta tagtaaccat gtctcttatt
     3061 attgcacctg gctcaattct tgcatgttca tttaaagtat tttttagagg aatagcagaa
     3121 tttcttctat catattctac atgagtatct gttatatcat tcccatgttt atctaatact
     3181 tccattatat cctcatagtc acctacaaat atataagaac cattacttcc aaatacctta
     3241 aatttatcag ttgattggaa gtgtaaagag ttagtattta catatacctt aacaggtgtt
     3301 ttctttttaa cttcttttat ataccttgct atttcataag catcgtttaa atttaccatt
     3361 tgttaattct ccttgtattt cattatattt cttttattat atacttattt gtcaatttta
     3421 gtatatactt acttcttatt atttatattt tattttagtt agtttttatt gtatagacat
     3481 agtattaaat aaatttatta tatatgtttg atttgtattg cgtattatta tatctatatt
     3541 gcatatgttt aatttatatt gtgtattatt atatttatac tattatccca acatgctgtc
     3601 catattataa aatcctggtt tttgcttaac taagtatttg gcagcagcta tagaaccact
     3661 tgcaaagata ccacgagatt gagcttgatg gcttattgta agaacctcat tgtctccagc
     3721 aaatagagca tcatgttcgc caacaatatt tccacctctt atagcatgaa taccaacttc
     3781 atttggttgt ctttttgcac tacgaccata tctaccataa ttattttcaa cgtttggcaa
     3841 aacctctttt atagcgttag caatcataac agctgtgcca cttggggcat ctacttttct
     3901 gttgtgatgt ttttctatta tttctatatc aaatccttct agtaatttag ctgcatcttt
     3961 aaccaatttt actaatacat ttacaccaag agacatatta tatgattgga atacaggaat
     4021 aactttagcc gcttcacgta ttttgttcat ttcgttatca ttatatccag tagtagcaat
     4081 tactaaaggt gttttagtct ttaaaacgta agataagata ttatctaaat tagagtgatg
     4141 agaaaaatct ataactacat cagcttcctc aactatagta ctcatatctt cataaatttt
     4201 aaggtcgcct tcatagctat ccagacctct agctgcaaca caaaccaatt ctaattcatt
     4261 atcttctctt atagtatcgg ctaaaatctt acccattttt ccatcataac cagttgctat
     4321 aacttttaac ataatttcct cctatgatta agggctaact tttgaccaaa cttacttttt
     4381 accatgcatt aatctttact atgcattaac ttttagtcca aagttaacta attctttctt
     4441 taacacttct aaatttgctg ggtccatttc tgctagaggt aatcttaaat ctccaacatt
     4501 gaatcccaat aaattcattg cagtcttaac tggtatagga tttacttcta taaataaagc
     4561 tgcgattaga gcatccatac caagttgtaa ttttctagaa ccttcaatat cgccttcaaa
     4621 gaatttagct accaaatcgt gagtttcttg agggcaaaca ttagcaagta ctgatataac
     4681 tccttgacct cctaaagata ataaaggaag tatagtatca tcattaccag agtagatagc
     4741 aaagtcatct ggaactaaac tagctatttc tgcaacttgt cctaggtctc cactagcttc
     4801 ttttacagca actatgttat caattttagc aagttcaact ataaggctag gacttatatt
     4861 tacacaagtt cttccaggga cattgtaaag tataattgga agtttaacac tgttagctat
     4921 tgtttcaaaa tgacgcttaa gtccagcttt attagcttta ttgtaataag gtgttattat
     4981 taatagagca tctactccta atttttcagc ttcttgactt aagttaactg agtgcatagt
     5041 atcattagaa ccacttccag ctataacagg aactctttta ttaacttttt caacaacata
     5101 cttaatagta gcaagttgtt cttcatcagt catagtatta gcttcaccag tagtaccaca
     5161 agatactata gcatcagtac cattagctat ttggtattca actaattcac ctaatttgtc
     5221 aaaatcaact ttgttatcct ttgtaaatgg tgtaactaga gcaacagcag aacctttaaa
     5281 tatcatataa aatcaatccc ctctttttta tttttgtgtt ttatattaca gttacttcta
     5341 atgcttgttt ttgagttact attaatattt tacaaaatta tatatttata caagtttgta
     5401 tattatacta aatcgtatga taaagccatt tcagctattt gaattgcgtt agttgcagca
     5461 ccttttctta tattgtcagc aacaacccaa agatttacac cattatcaac actaaaatct
     5521 cttcttattc ttccaacaaa tacttcatct ctatcatcaa attctacagc agttggatat
     5581 tcgtttttag caggattatc aactactaca acacctggag cttcttcaag tgtttttact
     5641 aaatcatcta actcaaatgg attgttaaac tcaacattta tagattcact atgaccattt
     5701 tttactggaa ctcttacagt agttgcagtt atttttaaat catagttatc aagtattttc
     5761 atagtttcat ttaccatttt catttcttct ttagtgtatc cattttcagt gaatgaatct
     5821 atatgaggaa gacagttgta agagatttga tgagggtaga atccagtagg attaccgttc
     5881 attcctttct ctaaatcttc aacaccttta acaccagaac cagatacagc ttggtaagta
     5941 gagtaaacaa ctctcttaat tttgtattta tcatcaagag ctttaagggg aaccatagct
     6001 tgtatagtag agcagttagg attagctatt atacccttat gattttttat ggcttctgga
     6061 ttaacctcag gaactactaa aggcacatct ggattcattc tccattgact agagttatct
     6121 actactaaga ttccatttga agcagctatt ggagcatact tttcactaat acttccacca
     6181 gcagagaata atgctatttg tatgcctcta tcagtaaatg aagtttcctt taattcttct
     6241 actatatatt ctttaccaca aaacattact ttagaaccag ctgatttaga agaagagaat
     6301 aaaaatagat tttctattgg aaaatttctt tcttctaata cttttaaaaa tgttctacct
     6361 accattccag tagcaccaac tattgctaca tttacttttt tcatataaat tcaccccaat
     6421 tttaaattat taaaacatta ttttatttta gttatacaag taagatatgt taatattttt
     6481 atatatccaa aaactttaat attatattaa caactttaat tatatacaaa aaacgtacaa
     6541 aggtatactt tgtacgtcta atttatcact caaagtaaac cctgtagctc atcacctaca
     6601 aaaataagtg acagtattac acatgttatg tgcaatccca gaaaatatta ttgcaagaaa
     6661 tattttcttc ggctgtaaat cctttttcca atcattaaca cctgccagct actattggat
     6721 actcttagtt acagctacct ctaccctagg ttaataggat attaaaattt gattattcta
     6781 ataataatac atatttaaga aaaaatcaac ttatttatat aaatattgct aaaacttaaa
     6841 tccaaaattt gtcaattctt gttttaacac attaagatta gtttcttcca tttcagctag
     6901 aggaagtctt aaatcaccaa cattaaaacc taaaatgttc atggcagttt taacaggaac
     6961 tggatttact tctataaata aagcagcaat taaagcatcc atatcaagtt gtaatttttt
     7021 tgagccttca atatcacctt caaagaattt agttactaaa tcatgtgttt ctttaggaca
     7081 tatgttagca agtacagaga taacaccact tccacctaat gataatagtg gtagtatagt
     7141 atcatcatta ccggagtata tagcaaagtc tttaggtact aatttagcta tttctgcaac
     7201 ttgagctaag tctccacttg cttccttcac agcaactata ttatctattt tagcaagttc
     7261 ggccacaaca gatggcttta tattcacttt agttcttcct ggtacgttgt ataaaataat
     7321 tggcaactta acgctatttg ctattgtttc aaagtgaagt ttaagacctt tctcattagt
     7381 cttattatag taaggagtta ttattaaaag accatccacc cctaattttt cagcttcttg
     7441 actcatatga acagacaaca tagtattgtt tgaaccagta cctgctataa caggtattct
     7501 cttattaact ttttcaactg tatattttat tacagcaaaa atttcagatt cactcatagt
     7561 agtcgcctca cctgttgttc cacaaacaac tagtgcatct gtgccattct caatgtgata
     7621 ttcgattaat tcacctaatt tttcaaagtt gacattatta tcctctgtaa atggggtaac
     7681 taaagcaaca gcagaacctt taaataacat ataatcaaat ctcctttttt atctaaattt
     7741 aattttttaa gtacaataat aattatagta caaattaatt aattttaata ggta
//
LOCUS       DAMJYN010000131         7743 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.137, whole genome shotgun sequence.
ACCESSION   DAMJYN010000131 DAMJYN010000000
VERSION     DAMJYN010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7743)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7743)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7743
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.137"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(234..2513)
                     /locus_tag="PC466_003400"
     CDS             complement(234..2513)
                     /locus_tag="PC466_003400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDF2770752.1"
                     /translation="MLSDAKNNRYGLSIIAVISILVITISCLIYGSRLNKTLGEETNQ
                     YLSEIANQSVNVLKKQINGDIKLLESISIFIEGEESFEVDNILSILKRQAINSSFKRM
                     GVILPNGTAYTTDGYIEDFSKRDYFLKSMQGEVVITEKLKDVIEDDKNTNSNINVYSV
                     PIYKDNEVKGVIFATHSTKLYEKILSVPTFNGKGYSYIARSNGNIVLNPSSKNANSTK
                     ENLFSYIGRSDSISKSSINNMKSNIKNFKSGSLSYSMFGKGYYLSYAPIGINDWYLFS
                     EVPKTAISEKSYAIIKLTLSACVVLIIIFTALTIYILFIHKKSKEKLEEFAFKDNVTG
                     IGNSNKFNLEGGKFLSSHEKKNLVLIYFDIDKFKLVNDRFGYEEGDRVLKEIAEIIKN
                     IFKEQSVFSRISNDNFAIIFEKKNNRESIIEICELIRKKLSMIKTSLGVELNLIPSIG
                     VYFVEEGETNISTCLDKAMIAKTTVKRKYLKVYEIYAENLKETLIEERDIEQEMHDAL
                     KNEQFKVYLQPKVDLSTTKIVGAEALVRWQHPKKGLISPGVFIPIFEKNGFITELDMF
                     VFAQVCKNFKRWENENFPTFPISINLSRVHLENPGFISELERITKEYEIEPNLIEIEL
                     TESAIFDNTKILFKIMQTLKSVGFKISMDDFGSGYSSLNMLKDMPIDVLKLDRQFFIT
                     VGNAKKSQIVVSSIVQMAKQLDIKVVSEGVETVEQAEFLRFIGCDMAQGFLFARPMPI
                     EEYEKLILDRYSLNRKETN"
     gene            complement(2784..4238)
                     /locus_tag="PC466_003401"
     CDS             complement(2784..4238)
                     /locus_tag="PC466_003401"
                     /EC_number="6.3.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HDF2770753.1"
                     /translation="MKLNDIIQGLDIINVKGELNIDINNVQYNSRKVTKGTLFICIKG
                     FVSDGHKYIKDAIEKGASAFLVEEDVEIKGCTFIKVKDTRKDMAKVADNFYNHPSQKF
                     NVIGVTGTNGKTSITTILNEILTLNKNKVGLIGTIKIFDGEKDIVSNSTTPESIDLQY
                     HFNNMLDNGCDYCAMEVSSHSLALNRVDETDFKLGIFTNLTPDHLDFHKDLEDYRKAK
                     EKLFFKTTMANIINIDDEGGKKIYENIKGINVPCYTYGVDTKADFMARDIKSDSDGVS
                     YRLITPSYEEVIFIPVPGMFTVYNTLAVIAACYVLGIPKPIYKEGLRLSNGVSGRFET
                     VPNDKGISVIVDYAHTPDALENVLKTTQQFAEGKIISVFGCGGDRDTEKRPLMGAIGQ
                     KYSDLCIITSDNPRTEEPEAIIKDILEGIDKKKENYHVVVDREQAIAEAISMAKKDDV
                     VIITGKGHETYQIIGKVKHHFDDKEVANECLSKM"
     gene            4402..5271
                     /locus_tag="PC466_003402"
     CDS             4402..5271
                     /locus_tag="PC466_003402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDF2770754.1"
                     /translation="MDNKIGYLNDNFKIFNIRDKKDIQFEYHNHDFNKIIIFINGNVT
                     YFVDGIPYKLKPWDILFISNNEIHKPVIDSNVFYERIAIWISPEFMKKNSDATSDLEK
                     CFKIATENKCNRLRLNIHDIESIKSFIEQINISESNTEFGNEILRNALFIQLMIFLNR
                     IFLKNENMESTEDVFYDETIKKVLNYINSNIDDKLSIDSISSEFFISKYYLMRKFKSH
                     TGTSIHNYIVQKRLILAKSLITNGYLMSEVCNKCGFNDYSSFVRAFKKNYGVSPKNYI
                     NNKNPLDITLLDE"
     gene            complement(5485..7557)
                     /locus_tag="PC466_003403"
     CDS             complement(5485..7557)
                     /locus_tag="PC466_003403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDF2770755.1"
                     /translation="MKKVFGVLQKVGKSLMLPVALLPAAGILLGVSNALAGDALLSHF
                     PALANPTFQLIISIMESSGQIIFNNLPLIFAVGVAVGLTEGEGVAALAAIVGFLILNT
                     SMGVMAGVTEDMVDNSMYASIVGIPTIQTGVFGGIIIGIVAAYLYKKFYKIELPQYLG
                     FFAGKRFVPIVTSLVAIAIGIILSFIWPPIQEGLLSFSKNVIEANQTLAAFMEGSLER
                     LLIPFGLHHVFHNPFWYQFGEYVNKAGELVMGDQKIFFAQLKDGVNFTAGTFMTGAFP
                     FMMFGLPAAALAMVHEAKPEKKKFVAGIMASAALTSFLTGITEPIEFAFLFVAPVLFA
                     IHCLFSGLSYAIMQLLGVKIGFTFSGGLIDFLLFGVLPNRTPWYLAILVGIGFAVLYY
                     SVFRFMIRKFNLKTPGREDESETNAEVIEMSKNELASEILIALGNKDNLKSLDACITR
                     LRLVVNDINKVDKEKLKLLGAAGVMVIGNNVQAIFGPKSDSIKSDIKDIIEGKTKVES
                     TVTKNVDKNKVKKNMEVANMENALVEKIDSLTNGEILDIEEVPDSVFSSKLMGDGFAI
                     KSSDGLIYSPVDGTIGVIFPTKHAIIIKSKKSGVEILIHLGIETVNLEGNGFEVFVNV
                     GDEVKAGEKLVKMDLEYIEKNCLSTISPVVFTNLEQNQKLSIKKGITTAKEENRVSIL
                     RYDIEKIG"
BASE COUNT         2631 a         1286 c          819 g         3007 t
ORIGIN      
        1 attactatta ttactatcta aagtattttg ctataatccc atatactctt acctcaaaaa
       61 cattcaaatg gaaaaaatac tacatattaa taaactttgc ccaataattc ctaaaataat
      121 atcctaacaa tgatttatgt ttttataata gtatattttt acataaaaaa gtgaacattg
      181 attaacaaag ttcacttttt tataaatttt tatgttataa ttcacaattt tatttaattt
      241 gtttcttttc tatttaaact atatctatct aatattaatt tttcatattc ttctattggc
      301 attggtctag caaataaaaa tccttgggcc atatcacaac ctataaacct taaaaactct
      361 gcttgctcta cagtttcaac accttctgaa acaactttta tatcaagttg ctttgccatt
      421 tgaacaatac ttgaaactac aatttgactc ttttttgcat ttcccactgt tataaagaat
      481 tgcctatcta atttcaatac atcaattggc atatctttaa gcatatttaa agaagaataa
      541 ccagaaccaa aatcatccat agaaatttta aatccaacag atttcaaagt ttgcattatt
      601 ttaaataata tttttgtatt gtcaaatatt gcactttctg tcaattcaat ctcaattaaa
      661 tttggttcaa tttcatattc ttttgttatt ctttcaagct cagaaataaa acctggattc
      721 tcaagatgta ctcttgataa gtttattgat ataggaaatg tggggaaatt ttcattttcc
      781 caacgtttaa aatttttaca aacttgggca aatacaaaca tatccaattc tgttataaaa
      841 ccatttttct caaaaatagg aataaataca cctggactta ttagaccttt tttgggatgt
      901 tgccaacgta caagcgcttc agcacctaca attttagtag ttgataaatc aaccttaggc
      961 tgtaaataaa ctttaaattg ttcatttttt aaagcatcat gcatttcttg ttcaatatca
     1021 cgttcttcta tgagagtttc ttttaaattt tcagcataaa tctcataaac ttttaaatat
     1081 tttcttttta ctgtagtttt tgcaatcata gctttgtcaa gacaggtaga aatatttgtt
     1141 tctccctctt caacaaaata tacacctatg gatggaatta aattgagttc tactcccaaa
     1201 cttgttttta tcattgacaa ttttttacgt ataagttcac atatttctat aattgactct
     1261 ctattatttt tcttttcaaa tattatagca aaattgtcat ttgaaattct tgaaaataca
     1321 gattgctctt taaatatatt cttaattatc tctgctattt cctttaatac tctatctcct
     1381 tcttcatacc caaacctatc atttactagc ttaaacttat ctatatcaaa ataaattaaa
     1441 actagattct ttttctcatg agaggataaa aattttcctc cttcaagatt aaatttattt
     1501 gaattgccaa tacctgtaac gttatcttta aaagcaaatt cttccaattt ttccttactc
     1561 tttttatgta taaatagtat ataaattgtt aatgccgtaa agattataat caacactaca
     1621 catgctgata atgtaagttt tataatagcg tatgatttct cagatatagc agttttagga
     1681 acttcagaaa aaagatacca atcattgatt cctattgggg cataacttaa ataatatcct
     1741 tttccaaaca tactataact taatgaacct gatttaaagt tttttatatt tgacttcata
     1801 ttattgatac tagattttga tattgaatca cttctgccaa tgtaagaaaa taaattttct
     1861 ttagtagagt tggcgttttt gctgcttgga tttaaaacaa tattaccatt acttctagct
     1921 atataagaat atccttttcc attaaatgta ggtacagaaa gtattttttc atacaacttc
     1981 gtactatgtg tggcaaatat aactccttta acctcattat ctttataaat tggcacagaa
     2041 tatacattaa tattactatt ggtattttta tcatcttcta ttacatcttt taatttttct
     2101 gttataacca cttctccttg cattgatttt aagaaataat ctcttttaga gaagtcttct
     2161 atataaccat ctgtagtgta tgctgtacca tttggtaaaa taactcccat tcttttaaat
     2221 gaactattaa tagcttgtct ttttagtata gaaaggatat tatctacttc aaaagactct
     2281 tctccctcaa taaatattga aattgactct agtaacttta tatctccatt aatttgtttt
     2341 tttaacacat tgacgctttg atttgctatt tctgaaagat attgattcgt ttcttcacct
     2401 aatgtcttat tcaaccttga accataaatc aaacaggaaa ttgtaattac taagatactt
     2461 atgacagcaa ttatggacaa accataccta ttattttttg catcacttaa cattatgctt
     2521 cctgcctttc tcgaatctat gtatgtataa tcattatctt atgacaatta ttgtaaacat
     2581 tttataataa tacttatttt tccatattta ctgtaattat acaaaattat aaactttatt
     2641 acaacaataa attaattaat atagatatta gggtttatat tattgcatta tctattttac
     2701 aatcatttac atataaaaaa atgtaatatc aaagtgaaac ttgatattac atttttgttc
     2761 ttgtattttg tttaattttt atgctacatt ttacttaaac actcatttgc aacttcttta
     2821 tcatcaaaat gatgcttaac tttacctata atttgataag tttcatgtcc cttacctgtt
     2881 ataattacaa catcatcctt ttttgccata cttatagctt ctgctatagc ttgttctcta
     2941 tcaacaacaa catggtaatt ttcttttttc ttgtcaattc cttcaagtat atcttttatt
     3001 attgcctctg gttcttcagt tcttggatta tcagaagtta taatacataa atcagaatat
     3061 ttttgtccaa ttgctcccat caaaggtctc ttttcagtat ctctatctcc accacatcca
     3121 aacacagaaa ttatttttcc ttctgcaaat tgttgagttg tctttagtac attttcaagt
     3181 gcatcaggag tatgagcata gtctacaatt acacttatac ctttatcatt tggaactgtt
     3241 tcaaaccttc ctgatactcc attagaaagt ctaagacctt ctttatatat tggtttaggt
     3301 atgccaagta catagcaagc agctataact gctaaagtat tatatactgt aaacattcct
     3361 ggaactggta taaatattac ttcttcatat gaaggtgtta ttaatctata agatactcca
     3421 tccgaatctg attttatatc tctagccata aaatcagcct tagtatcaac accataagtg
     3481 taacaaggta catttatacc ttttatattt tcatatatct tttttccacc ttcatcatct
     3541 atgtttatta tatttgccat agtagtctta aaaaataatt tttcttttgc ttttctataa
     3601 tcctctaaat ctttatgaaa atctaaatgg tctggtgtta aatttgtaaa tatgcctagt
     3661 ttaaagtctg tttcatcaac tctatttaat gccaatgaat gtgatgaaac ttccatcgca
     3721 cagtagtcac atccattatc caacatatta ttaaaatgat attgtaaatc tatactttct
     3781 ggagttgttg aattggaaac aatgtctttt tctccgtcaa aaatttttat agttcctata
     3841 agtccaactt tattcttatt taaagttaat atctcattta gtatagtagt tatactagtt
     3901 tttccattag tacctgtaac tcctataacg ttaaatttct gagatggatg attataaaaa
     3961 ttatcagcta cttttgccat atcttttctt gtatctttta cctttataaa tgtacatcct
     4021 tttatttcta catcttcttc aacaagaaat gcacttgctc ccttttctat ggcatctttt
     4081 atatacttat gaccatctga cacaaatcct tttatacata taaataatgt accttttgta
     4141 acctttcttg aattatattg tacattatta atatctatat ttaattcacc cttgacattg
     4201 attatatcca acccctgtat aatatcattt aatttcataa atgctttcct ccctttaaac
     4261 tctttctgct aaaattacac tacatataat attatattaa gaatttttta ctatgtgaat
     4321 ggttaaaaat gcttgaaata ttgcaaaaaa tgctctataa ttttctataa tataactgag
     4381 gaaaggtctt ctataaaaac tatggataat aaaatcgggt acttaaacga taactttaaa
     4441 atatttaata ttagagataa aaaagatata caatttgaat accataatca tgattttaat
     4501 aagataatta tatttataaa tggaaatgta acttattttg ttgatggtat tccctataaa
     4561 ctaaagcctt gggatatact ctttatcagc aataatgaaa tccataaacc agttatagat
     4621 tcaaatgtct tttatgagag aattgcaata tggattagcc cagaatttat gaaaaaaaat
     4681 agtgatgcta ctagtgactt agaaaaatgt tttaaaatag ctacggagaa taaatgcaat
     4741 agattgcgtt taaatataca tgatattgaa tctattaaga gttttattga gcaaataaat
     4801 atttccgaat ccaatactga atttggaaat gaaatattga gaaatgcatt atttatacaa
     4861 cttatgatat tcttaaacag aattttccta aaaaatgaaa atatggaatc aacagaagac
     4921 gttttttatg atgaaactat taagaaagta ttaaactata taaattcaaa tatagatgat
     4981 aagctttcaa tagatagcat atcgtctgaa ttttttataa gtaagtatta tcttatgaga
     5041 aaatttaaat ctcatactgg aacgtctata cacaattata tagttcaaaa aagattaatt
     5101 ttagcaaagt cactaataac caatggttac cttatgagtg aagtttgtaa taaatgtgga
     5161 ttcaacgatt attctagttt tgtaagggca tttaaaaaaa actacggtgt atctcctaaa
     5221 aattatataa acaataaaaa tcctttagat attactcttt tagatgaata gataatttat
     5281 gtaaatttta ttttaataaa aacttgaagt attagtgtat ttatcttact aatacctcaa
     5341 gttttttaat gttttaaaat atatcaaaat ataatgatat atatttctat tacttaaaat
     5401 atatattaaa taaattgcat gttaactgaa cctatttata tatttattaa atctcacata
     5461 acttttagtt atactatcat atagctatcc tattttttca atatcatatc ttaatatact
     5521 tactctgttc tcctcttttg ctgtagttat tcctttttta atgcttaatt tctgattttg
     5581 ttctaaattc gtaaatacta caggacttat tgttgataga caattttttt caatatattc
     5641 taagtccatt ttaactaatt tttctcctgc ttttacttca tctcctacat tcacaaatac
     5701 ttcaaatcca tttccttcta aatttacagt ttctatccct aaatgtataa gtatttctac
     5761 tccacttttt ttggatttta ttattattgc atgcttagtt ggaaatataa ctccaatagt
     5821 tccatcaact ggtgaataaa tcaatccatc actagattta attgcaaatc catcccccat
     5881 cagtttactt gaaaatacag aatctggcac ttcttctata tctaatatct ctccatttgt
     5941 taatgaatca atcttttcta ctaaagcatt ttccatattg gcaacttcca tatttttttt
     6001 cactttattt ttatcaacat ttttagtaac agtactttca acctttgttt ttccctctat
     6061 tatatctttt atatcagact ttattgaatc cgattttggt ccaaatatag cttgaacatt
     6121 gttgccaata accataacac ctgctgctcc aagtaatttc aatttttctt tatctacttt
     6181 atttatatca tttacaacca atctaagtct tgttatacac gcatctaggc tctttaagtt
     6241 gtctttattt cctaaagcaa ttaaaatctc tgatgctaat tcattcttag acatttcaat
     6301 gacttcagcg ttagtttctg actcatcttc tcttcctggt gtctttaaat taaattttct
     6361 tatcataaat ctaaatacac tatagtataa tactgcaaaa ccaataccta ccaagatagc
     6421 caagtaccat ggagttctat taggaagaac accaaataat aagaaatcta ttaatcctcc
     6481 tgaaaatgtg aatccaattt taactcctaa taattgcata attgcgtatg ataaacctga
     6541 aaataaacaa tgtattgcaa ataatactgg tgcaacaaat aaaaacgcaa actctattgg
     6601 ctcggttatt cctgttaaaa aagaggttaa tgctgctgat gccattatac ctgctacaaa
     6661 ttttttcttt tctggctttg cttcatgcac catagcaaga gctgctgctg gaagaccaaa
     6721 catcataaat ggaaatgcac ctgtcataaa agtacctgct gtgaaattta ctccatcttt
     6781 aagttgagca aagaatatct tttggtcacc cattacaagc tcaccagctt tatttacata
     6841 ttctccaaat tgataccaaa atggattatg gaaaacatga tgcaaaccaa atggtattaa
     6901 tagtctttcc aaagaacctt ccataaatgc tgctagtgtt tgatttgctt ctataacatt
     6961 ttttgagaaa ctaagtaatc cctcttgtat tggaggccaa ataaaagaca atataattcc
     7021 tattgctata gcaactaatg aagtaacgat tggtacaaat cttttacctg caaaaaaacc
     7081 tagatactga ggtaattcaa ttttataaaa ctttttataa agataagcag ccactatccc
     7141 tataataata ccaccaaata cccctgtttg aattgttggt attccaacaa tacttgcata
     7201 catagaattg tctaccatat cttctgtaac acccgccata acacccatag atgtattgag
     7261 aattaaaaaa cctactatgg ctgccaatgc tgcaacacct tctccttcag ttaaaccaac
     7321 agctacccca actgcaaata taagtggtaa gttattaaat ataatttgac ctgaactttc
     7381 cattatactt attataagtt gaaatgtagg attcgccaaa gctggaaaat gagacaacaa
     7441 tgcgtctcct gctaaagcat tactcacgcc aagtaatata cctgctgcag gaagtaatgc
     7501 aactggtagc attagagatt ttcctacttt ttgtaaaaca ccaaatactt ttttcattta
     7561 cttttctctc cttattattt tatatttttt taaataaaaa agacttaagt ttataaaaag
     7621 ttacattagt atacttaatt ctaaaattaa acttatgtta atataaataa acctatatta
     7681 acctaatttc agaattaaaa ataaactatt ataatttttt tataaacata agtcttgcct
     7741 gca
//
LOCUS       DAMJYN010000132         7703 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.138, whole genome shotgun sequence.
ACCESSION   DAMJYN010000132 DAMJYN010000000
VERSION     DAMJYN010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7703)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7703)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7703
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.138"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            107..2335
                     /locus_tag="PC466_003404"
     CDS             107..2335
                     /locus_tag="PC466_003404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HDF2770756.1"
                     /translation="MRHLKKTNSLKEILNWNNIKNLRPSKGLKNILEIFKSDLKDIRG
                     NYAVLVIVLGLAFLPSLYAWFNIKASWDPYGSTANMLVAVTNEDKGNEIAGQKINVGD
                     QLIEQLKDNKSLGWQFVDEKTALEGVKKGTYYASLKIPKNFTKDLTSLITDDVKKGEI
                     IYTVNEKINAVAPKITDKGASTIQLQVNQTIVKTVSEIVLGISNGVGAGIEHSLPKLT
                     KVENSLIDLQKRFDHINKTVDLASDATSKLSDTVKDIKSDLPTIKKTLNDTKLLSSDL
                     KKFLEDTNDNLDELSPLIKSDLNLMVDLSSSASSLTLNLIDAVNSGSEDVPKLIDNLS
                     EKLSNLQSLNDTLVDFLTKLNQLTSNNRLDDVIDNLEDSSNKIDSSISTLNDIKNKVI
                     SGQQPSISALNNVLSLSNGIGRINLNILNNFDSKISKPINSIFANSIKVANDIITVLD
                     KAEAKLPKVEEILTTSLKLSGNAQESISLIRERLPLAKGMLDDLIDTLSKISNGEDMK
                     KLVSLLESDILTKSNFLKEPVEVKTEKLYPIENYGSAMTPFYSVLSTWVGILLISALL
                     STSVHGNYKPYEIYFGRGLTFLSIALVQGFIIGTGDILLLGVTAKHPILLIVLLMFTS
                     MVFNFIVYSLVSVFGNVGKAIAIVLLVVQIGSSGGTFPIQVTPTFFQRINPIMPFTYA
                     IGATREAVGGIYAPNLTKDILVLLLFMILSICLNVLLKGPINRVIKPFNDKFGDSNLT
                     GH"
     gene            complement(2573..2872)
                     /locus_tag="PC466_003405"
     CDS             complement(2573..2872)
                     /locus_tag="PC466_003405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HDF2770757.1"
                     /translation="MYKNINKKQLKEMMKNEKDVLLLDVRTKDEFKEYKIENAINISL
                     QDLINNIDEIYDYKDKKVVVYCRSGHRSVTACNLLAEEGFEHLYNLNSGIIDYMS"
     gene            3079..6120
                     /locus_tag="PC466_003406"
     CDS             3079..6120
                     /locus_tag="PC466_003406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp20"
                     /protein_id="HDF2770758.1"
                     /translation="MFKQRISKLLSSTLVLSMLFTAAPNITFADNTKDNSEKYQSSDI
                     ELHDYSKNAESYTKTKALAKEKIQTLLSKYGAVSAQYALIDNGKIEISGNGGVYSKQD
                     NKNLNKDNMYSIASISKMFTTTAVMKLVDDGKLNLDTPVVKYIPEFKMADDRYKEITP
                     RMLLNHSSGLMGSSFKNTILLADNDSYGHDNFLKELQKQRLKAKPGAFSVYCNDGFTL
                     AEILVERVSGMSFTNFLDKYINNPLNLQNTKTTENSFDSSKLAKAYVPYWEDAVPQDN
                     LNAIGAGGLYSSAENLCTFAQTFMKNSNGILSPASVKAMENKEYLNGLWPEGEDSILG
                     YGLGWDCVNTYPFNQYNLKALTKGGDSLLFHSNLIVLPDENMAVAVLSSGGSSQLNEI
                     IGQEILLSALKEKGKIKEIKPDKTFSKPQQVKMPSSLKENSGLYASSNMIKVDVNDNG
                     TLTVSSPYIENGPEDKYVYIGQDRFVSEKGNSCLKFVKEKNNITYLNMSSYDDVPGLG
                     QTASLYYVAQKVDDNNISNSVKEVWKKRSGKGYYLVDEKYTSQSYMFGSVKASFSLSD
                     ETPGYIVNTKIMDENNSNAFIEIPGVIGRDLSDIKLHKENGTEYLSFGTLTYVSEDSI
                     TNLPAEKSFTCELESNGYAKWYKIGDDIANKKIEVNLPQNSAFAVYDDKGVPVNYSLV
                     TKNNRVRLPKGGVIVFLGSPNARFEVTYQDEVNASALTGTDRYETSIKISQAGWENAE
                     NAVLINDSAIADALAATPFAYKKNAPILLTGSSQINEKTLAELKRLKVKNVYVVGGEA
                     SINEKSLDTIKSNNISVSRISGSDRYQTSMNIAKELNNISNISKISVVNGEKGLADAV
                     SIGAVSAQNDMPIILTNENSNITEINNLFKNKKIDKSYVIGGEYTVSKNIESKLQNPQ
                     RISGNTRNETNAKVIKEFYKDSKIDNLYVAKNGMNKQDDLIDGLSVGVLAGKTKSPVM
                     LVGNSLDYNQKELFKTMRFKSVTQIGGNGNENSFKQIKEIA"
     gene            complement(6281..7555)
                     /locus_tag="PC466_003407"
     CDS             complement(6281..7555)
                     /locus_tag="PC466_003407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HDF2770759.1"
                     /translation="MITISHITAKNMYKSLEERINKFPQGAPPSDTLYKILNVLYTEQ
                     EAKLVAQLPIKPFRVKTAAKIWSVSESEAYRVLDKLASKALILDIEDNKGKKYIMPPP
                     MAGFFEFAMMRTRHDIDQKLLAELYYQYMNVEEDFIKDLFYSTETKLGRVYVQEEVLT
                     NDNEVSILDYERATHIIDESTHIGISMCYCRHRMQHVGKACDAPMDICMTFDNVANSL
                     INNKFARRVDKIECKELLHQAYEHNLVQCGENVRKGVTFICNCCGCCCEAMVAAKRFG
                     NLHPVQTTSFIPNINHENCVKCGKCITACPIDAISKVKEDGKEYIKIDEDRCLGCGVC
                     VRNCHKNSIMLLKRDEKIITPANSVHRAVLMAIEKGQLQNLIFDNNALASHRAMGAIL
                     SAILKLEPAKKILASKQLKSVYLDKLLSMNDK"
BASE COUNT         2851 a         1075 c         1104 g         2673 t
ORIGIN      
        1 tattaaaatt aagacaaaat tttaacttta ctatttgtgt aaaaagtaat ataatttaaa
       61 attgattata aatctaactt ttttctttat caaaatattt taggaggtga gacatttgaa
      121 aaaaactaat agtttaaaag aaattttaaa ctggaataat atcaagaatt taagaccttc
      181 aaagggttta aaaaatatat tagaaatttt taaaagtgac ctaaaagata tacgtggcaa
      241 ttatgccgta cttgtaatag ttttaggtct tgctttttta ccatctctgt atgcttggtt
      301 caatataaag gcatcttggg acccttatgg aagcactgct aatatgcttg tagcagtaac
      361 aaatgaagat aaaggaaatg aaatagcagg acaaaagatt aatgtaggag accaattaat
      421 tgaacaactc aaagataaca agagtttagg ttggcagttt gtagatgaaa aaactgctct
      481 tgaaggtgtt aaaaaaggta cttattatgc atcacttaag attccaaaaa attttacaaa
      541 agatttgaca tctttaatta cagatgatgt taaaaaaggc gaaattatct atactgttaa
      601 tgaaaaaata aatgcagttg caccaaagat tacagataaa ggtgcttcta caatacaact
      661 acaggttaat cagactatag taaaaacagt tagtgaaatc gttcttggta tatcaaacgg
      721 agttggtgca ggaattgaac acagtcttcc aaaattgaca aaagttgaaa attcccttat
      781 tgaccttcaa aagagatttg accatataaa taagactgtg gatttagctt ctgatgctac
      841 ttcaaaatta tctgatacag ttaaagatat taaatctgat ttacctacaa ttaaaaagac
      901 tctgaatgat acaaaactat tatcaagtga cttaaaaaaa ttcttagagg atacaaatga
      961 taatttagac gaactttctc ctcttattaa gtctgactta aatttaatgg ttgacctttc
     1021 atcttctgct tcttctctta cattaaattt aattgatgca gtaaatagtg gcagtgaaga
     1081 tgtacctaag ttgatagata atttatcaga aaaactttct aatttgcaat ctttaaacga
     1141 tactttggtg gactttttaa ctaaattaaa ccaacttaca tcaaataata gattggatga
     1201 tgtaatagat aatcttgaag actctagcaa taaaatagat tcatctatat caacattaaa
     1261 tgatattaaa aacaaagtta tatctggaca acaaccatct ataagtgctt tgaataatgt
     1321 tttaagtcta tcaaatggta ttggaagaat taatttaaat attttaaata attttgactc
     1381 aaaaatatca aaacctataa atagtatatt tgcaaacagt ataaaagtag caaatgatat
     1441 aattactgtt ttagataagg cagaagcaaa acttccaaag gttgaagaaa tacttactac
     1501 ttctctaaaa ctttcaggaa atgcacagga aagtatatca ttgataagag aaagacttcc
     1561 tttagcaaaa ggaatgttgg atgatttgat tgatacttta agcaaaatta gtaatggtga
     1621 agatatgaaa aaattagtca gcttgcttga aagtgatata ttgacaaagt ctaatttctt
     1681 aaaagaacct gttgaggtga aaacagagaa attatatcca attgaaaatt atggttctgc
     1741 aatgacacca ttttatagtg ttctttctac atgggttggt atattactta tttcagcact
     1801 attgtctaca tctgtacatg gaaactataa accttatgaa atttactttg gaagaggtct
     1861 tactttttta agtatagctc ttgtccaagg ttttataata ggaactggag atatattatt
     1921 gttaggagta acagcaaaac atccaatttt attgatagtt ctgcttatgt ttactagtat
     1981 ggtatttaac tttatagtgt attctttagt ttctgtattt ggaaatgtag gaaaagcaat
     2041 tgcaatagta ctattagtcg ttcagattgg ttcttctggt ggtacattcc ctatacaagt
     2101 tacacctaca ttcttccaaa gaataaaccc tataatgcca tttacctatg caataggtgc
     2161 tacaagggaa gcagttggtg gtatatatgc tccaaatcta actaaagata tactagttct
     2221 attactattt atgattctgt ctatttgttt aaacgtactt ctaaaaggac ctataaatag
     2281 agttataaaa ccatttaatg ataaatttgg cgatagtaat ttaactggtc attaaaaaat
     2341 taattctgtc tttaaatata tttttttaat aatattctaa gttcatatta aaaggtagta
     2401 gctaaaaagc tactaccttt ttccaactta aaaactaata tttactacaa aaactgtcat
     2461 agaaaaaagc gaaaaaattc gttctttcct aaatttatct tataaatatt tagatatatt
     2521 cctacttaat aaacagagct atacatagta tttaatgtat aacttacctt atttaactca
     2581 tataatcaat tattcctgaa tttaaattat ataaatgctc aaaaccttct tcagctaaca
     2641 aattacatgc agtaacactt ctatgaccac ttctgcaata aactactact ttcttatctt
     2701 tataatcgta aatttcatct atattattga ttaaatcttg taaagatata tttatagcat
     2761 tttctatttt atattcctta aattcatctt tagttcttac atctaataat aaaacatcct
     2821 tttcattttt catcatttct ttaagttgct tcttatttat attcttatac atatgtctaa
     2881 aattcctcca ttttatttat atattaccta taccctttat tctttataca acaacaaata
     2941 ttatttttat atttttctct gttatataaa aagctatact tataaaagct ttttttattg
     3001 ataataatct gttgattaaa ataattaaga atgttatgct aattataaat tattaaaaag
     3061 ggaaagaggt aatgtaatat gtttaagcaa aggatctcta aattattatc tagtacatta
     3121 gtattgagta tgttatttac tgctgctcca aatattactt ttgctgataa tacaaaagat
     3181 aattccgaaa aatatcaaag ttctgatata gaattacatg attatagtaa aaacgcggaa
     3241 tcttacacaa aaactaaagc tcttgctaaa gagaaaatcc aaactttgct atcaaagtat
     3301 ggtgctgtaa gtgctcaata tgctttgatt gataatggca aaattgagat ttctggtaat
     3361 ggtggagttt acagcaaaca ggataacaaa aacttaaata aggataatat gtatagtatc
     3421 gcatctatca gtaaaatgtt tactacaaca gctgttatga agttggttga tgatggaaaa
     3481 ttaaatttag atactcctgt tgtaaagtat atacctgaat ttaaaatggc tgatgataga
     3541 tacaaggaaa tcactccaag aatgttatta aatcattcat cagggttgat gggaagtagt
     3601 tttaaaaaca ctattttatt agcagacaat gattcttatg gtcatgataa tttcttaaaa
     3661 gaattacaaa aacaaagatt aaaagctaaa ccaggagctt tttccgttta ttgtaatgat
     3721 ggatttactt tagctgaaat tttagtagaa agagtatctg gtatgtcatt tactaatttt
     3781 cttgataaat acataaataa tccacttaac ttacaaaata caaaaactac agaaaatagt
     3841 tttgatagtt caaaactagc aaaagcatat gtaccttatt gggaagatgc agttccacaa
     3901 gataacctta atgctatagg tgcaggtggt ttatattcaa gtgcagaaaa tctatgtaca
     3961 tttgcacaaa catttatgaa aaattcaaat ggtattcttt ctcctgcttc agtaaaagct
     4021 atggaaaaca aagaatattt aaatggtcta tggcctgaag gagaagattc tatacttgga
     4081 tatggtttag ggtgggattg tgtcaacact tatccattta atcagtataa tttaaaagct
     4141 cttacaaaag gtggagactc tttattattc cacagtaatc ttatagttct tccagatgaa
     4201 aatatggcag ttgcagttct ttcttctggt ggaagtagtc aacttaacga aataattgga
     4261 caagaaatct tactatctgc attaaaagaa aaaggtaaaa ttaaagaaat aaaacctgat
     4321 aaaacattta gtaagccaca acaagttaaa atgcctagct ctctaaaaga aaatagtggt
     4381 ctttatgctt cttcaaatat gataaaagta gatgttaatg ataatggtac tttaacagta
     4441 tcttctcctt atatagaaaa tggacctgaa gataaatacg tatacatagg tcaagataga
     4501 tttgtatctg aaaagggtaa cagttgttta aaatttgtaa aagaaaaaaa taatatcaca
     4561 tatttaaata tgagctctta tgatgatgtc cctggattag gtcagacagc aagtttatac
     4621 tatgtagctc aaaaagtaga tgacaacaat atatcaaata gtgtcaaaga agtgtggaaa
     4681 aaaagaagtg gcaaaggtta ctatctagtg gatgaaaaat atacttctca aagctatatg
     4741 tttggctctg taaaagcaag ttttagtctt tctgatgaaa ctccaggtta tatagttaac
     4801 actaaaataa tggatgagaa taactcaaat gcttttatag aaatacctgg tgtaataggt
     4861 cgtgatttat ccgacattaa acttcataaa gaaaatggta cagagtattt atcttttgga
     4921 acactaacgt atgttagtga agattctata actaatttgc cagcagaaaa atcttttact
     4981 tgtgaactag aatccaatgg ttatgcaaaa tggtataaga ttggtgacga tatcgcaaat
     5041 aaaaaaatag aagttaatct tcctcaaaat tcagcttttg ctgtttatga tgataaaggt
     5101 gttcctgtaa actattcttt agttacaaag aacaatagag ttagattgcc aaaaggaggc
     5161 gtaattgttt tcttaggaag tccaaatgct agatttgagg ttacatatca agatgaagta
     5221 aatgcaagtg cacttacagg aactgataga tatgaaactt ctattaagat aagtcaagca
     5281 ggttgggaaa atgctgaaaa tgcagtttta ataaacgatt cagcaattgc agatgctttg
     5341 gccgcaacac catttgcata caagaaaaac gctcctatat tattgactgg aagctctcaa
     5401 ataaatgaaa aaactttggc tgaattaaag agattaaaag ttaaaaatgt atatgtagtt
     5461 ggtggagagg cttctataaa tgaaaaatct ttagatacta taaaatcaaa caatatctct
     5521 gtatctagaa tttcaggaag tgatagatat caaacttcta tgaacattgc taaagaattg
     5581 aacaatatta gcaatatatc aaagatttca gtagttaatg gcgaaaaagg attagccgat
     5641 gcagtaagca ttggagctgt atcagctcaa aatgatatgc ctataatact tactaatgaa
     5701 aatagtaata taactgaaat aaataactta tttaaaaaca aaaagattga taaatcttat
     5761 gtaatcggtg gagaatatac agtttctaaa aatatagaaa gtaaacttca aaatccacag
     5821 agaatatcag gtaacactag aaatgaaact aatgcaaaag taataaaaga attttacaag
     5881 gattctaaga tagacaattt atatgttgct aaaaatggaa tgaataaaca agatgattta
     5941 atagacggat tatctgttgg agttttggct ggaaaaacta aatctcctgt aatgctagta
     6001 ggaaactcac tagattataa tcaaaaagaa ctatttaaaa ctatgagatt taaatctgta
     6061 acacaaattg gtggaaatgg aaatgaaaac tcatttaagc aaataaaaga aatagcttaa
     6121 cataactaaa aaaggctgta ttcaagtaat attaattgaa tatagccttt ttttatttaa
     6181 gttataagtt ttatatgtgt aaaaattaaa tttaaatatt aaatgataag tttattaaga
     6241 tatagataag tctaaaactt tgcctttttt aagttagttt ctatttatca ttcatactta
     6301 acaatttatc taaatatact gactttaatt gtttactggc taaaatcttt ttagctggtt
     6361 caagctttaa tatagctgac agtatagctc ccatagctct atgactagcc agagcattat
     6421 tatcaaaaat taaattttgt aactgccctt tttcaattgc catgagaact gctctatgta
     6481 ctgaatttgc tggagttatt attttttcat ctctctttaa taacataatg ctatttttat
     6541 ggcaatttct aacacaaact ccacaaccta aacatctatc ctcatcaatt tttatatatt
     6601 ctttaccatc ttccttaacc ttgcttatcg catctattgg acatgcagtt atacatttac
     6661 cacactttac acaattttca tggtttatat ttggtataaa acttgttgtc tgtactggat
     6721 gaagatttcc aaatctttta gctgctacca ttgcttcaca gcaacatcca cagcaattac
     6781 atataaacgt aacccctttc ctaacatttt ctccacattg aactaagtta tgttcatatg
     6841 cttgatgaag tagttcttta cattctattt tatccacacg tcttgcaaat ttattattta
     6901 ttaaagaatt tgctacattg tcaaacgtca tacatatatc catgggagca tcacaagctt
     6961 ttccaacatg ttgcattcta tgtctacagt aacacatact tatacctata tgagttgatt
     7021 catcaattat atgagtagcc ctttcataat ctaaaatact aacctcatta tcattagtta
     7081 aaacttcctc ttgaacgtat actcttccaa gcttcgtttc tgttgaataa aataaatctt
     7141 tgataaaatc ttcttctaca ttcatatatt gatagtaaag ttctgccaaa agtttttggt
     7201 ctatatcgtg tctcgttctc atcatggcaa actcaaaaaa accagccatt ggaggaggca
     7261 ttatatattt cttcccttta ttatcttcta tatctagtat cagagcctta ctagcaagtt
     7321 tatccaatac tctatatgct tcactttcac ttacactcca aattttagct gctgttttta
     7381 ctctgaaagg ctttattgga agctgagcaa ctaacttcgc ctcttgttct gtatatagta
     7441 catttagtat tttgtataat gtatcagatg gtggagcacc ttgtggaaac ttgtttattc
     7501 tttcctctaa acttttatac atattcttcg cagttatatg agaaatagta atcaccttct
     7561 ttttcttttg ttttcaaata aaatcaaata ttctttctta ttatatattc tcttacttta
     7621 tataatacca attctttcta aatagttaaa tacctctagt aatttattat tagatttctt
     7681 atataaataa aaaatcattt aag
//
LOCUS       DAMJYN010000133         7696 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.139, whole genome shotgun sequence.
ACCESSION   DAMJYN010000133 DAMJYN010000000
VERSION     DAMJYN010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7696)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7696)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7696
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.139"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            59..1117
                     /locus_tag="PC466_003408"
     CDS             59..1117
                     /locus_tag="PC466_003408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium channel family protein"
                     /protein_id="HDF2770760.1"
                     /translation="MNCKWISKIDERKKCHREADSSGYCIFHKENKSDEEIQLMMDTI
                     HKEEISEFNGFVFENEFNAEEILTYNYKILDFSESIFKQKANFKKYIFKKNIIFNYTE
                     FRDKVLFNGCIFLENCDFNRTIFSKNYINDRIFEKVKFKGPDLVVNKVENFPRMDGII
                     FSMCTKFVLKNVEYGKSEYEHGKINYRIARNQATKIGEYEMIGFYYYKERIYSSKIMK
                     RSNYPTFSDYLVEKFFDQIARYTTGYGEKPWNILLVIIAIISVFALLYLFVGIESSNS
                     TLVALDINNIGDYSLSEIFKMYMDLWYFSMATFSTVGYGDMVATSLIGKALAGIEVFF
                     GVTIGAIWASVIIKRMIR"
     gene            1221..2405
                     /locus_tag="PC466_003409"
     CDS             1221..2405
                     /locus_tag="PC466_003409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HDF2770761.1"
                     /translation="MKNALKKIISLAMILVFIIPNYSYADGKSVDKYSKTSILIDQET
                     GRVLYSKEPDMKVPLASLSKMMTFLLAIEAIENKEVKETDKVKIDKSIASVKGSSYKL
                     KDGEEVPLIELMRGLMIVSGNDAAIAIAKHICKTKEAFVDRMNKKAKEIGMSNTHFLN
                     PNGLPIYDLSNPKKPAKENISTAKDIAILGKYMFDHYEKQVTAITDMETYTNSDRSFE
                     KSNTNALLRIIPEVDGIKTGYTGNAGYCLSFSMVVNKNEKNEKKRRVIGVVLGTNHKN
                     KRTSASLALLKYGKENFNMKKVIDKDSFIGKKYIKGMKELEVTLKAKDELYTILKDDE
                     SIKSEVKIKNIEYPVKKGDTMGVIKYYTSSGDLLGSVDIVSNNSIDNVSLKTKLKMKF
                     AN"
     gene            2612..3325
                     /gene="rpsB"
                     /locus_tag="PC466_003410"
     CDS             2612..3325
                     /gene="rpsB"
                     /locus_tag="PC466_003410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HDF2770762.1"
                     /translation="MSVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIYIIDLQ
                     KTVKKVEEAYKFTKEVAETGKPILFVGTKKQAQDAIKDEAERCGMYFVNERWLGGMLT
                     NHKTIKTRINKLRELEKMEEEGVFNVLPKKEVIKLRAEKEKLEKYLGGIKDMPELPGA
                     MFVVDPRKENIAIQEAHRLGIPVVGIVDTNCDPEQLDFAIPGNDDAIRAVKLITGAMA
                     TAVIEGRQGAEEEVAEDQE"
     gene            3404..4315
                     /locus_tag="PC466_003411"
     CDS             3404..4315
                     /locus_tag="PC466_003411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HDF2770763.1"
                     /translation="MANITAQMVKELRESTGAGMMDCKKALQEAEGNMEKAVDLLREK
                     GLSKAAKKAGRVAAEGLVAIEMNDDNTVASMVEVNSETDFVAKNEDFKVFVKDAACMA
                     LATDKEDIASLLGETHKEGITLQEVLNNRVAKIGEKLDFRRFAKVVTNGQVAGYIHGG
                     GKIGVLVEMETEARDAKVLELGKDVAMQVAAMNPKYVSRDEVDAEYIAHETEVLTQQA
                     LNEGKPANIVEKMVKGRLEKELKEVCLLEQTFVKNPDITVKQLVADVAKAVGSDIKVV
                     KVVRFEVGEGIQKREENFAEEVAKQLK"
     gene            4400..5104
                     /locus_tag="PC466_003412"
     CDS             4400..5104
                     /locus_tag="PC466_003412"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HDF2770764.1"
                     /translation="MDKPMYKRVLLKLSGEALAGERGFGINNDVVNDIAIAIKKIQEI
                     GVEVAVVVGGGNFWRGRTSEGMDRTTADYIGMLATVMNAMALQDALENIDVATRVQTA
                     IDMRQIAEPYIRRRAVRHLEKERVVIFGAGTGNPYFTTDTTAALRAAEMEAEVILLAK
                     NVDAVYDKDPKVHADAKKFTELSYMEVIQKELKVMDSTATSLCMDNKIPIKVFELTTE
                     NIIRAVKGENIGTTVK"
     gene            5130..5687
                     /gene="frr"
                     /locus_tag="PC466_003413"
     CDS             5130..5687
                     /gene="frr"
                     /locus_tag="PC466_003413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HDF2770765.1"
                     /translation="MKLEIHKQLEEKMNGTIDALKFEFGTIRAGRANAQMLDKIRVDY
                     YGTPTPINQIGAISVPEPRILMISPWDKSAMHEIEKAIANSDLGLNPSNDGEVIRLSV
                     PALTEERRKELAKKASKAAEEFKVRIRNERRDANEKIKKMEKGGELTEDELKKAQDEV
                     QKMTDKFIKEIDTLLSKKEKDIMEV"
     gene            5690..5893
                     /locus_tag="PC466_003414"
     CDS             5690..5893
                     /locus_tag="PC466_003414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770766.1"
                     /translation="MKKYYNLLGLHVDEVKQYFDEQNINYTVKSIEGKKDKEKLVVPR
                     VIKISEIGDSVELIITYFSDSLV"
     gene            5922..6656
                     /locus_tag="PC466_003415"
     CDS             5922..6656
                     /locus_tag="PC466_003415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HDF2770767.1"
                     /translation="MNNNIIYDIDLNNIPTHIAIIMDGNGRWAKARFLPRTAGHKAGV
                     ETIRDIVKECSKLGVKHLTLYAFSTENWKRPKLEVDTLMNLLSTYLRNEIAELHQNNV
                     KVTAIGDISALPKTCIRELNSAKELTKNNTGVNLNLALNYGSRADIKNALIDIVKNCE
                     SGKIDINNIDEDIIKNYLSTKSIPDPDLVIRTSGEQRLSNFLLWEVAYSEFYFTDIHW
                     PDFKKEELQKAIYVYQRRDRRFGGLK"
     gene            6669..7448
                     /locus_tag="PC466_003416"
     CDS             6669..7448
                     /locus_tag="PC466_003416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HDF2770768.1"
                     /translation="MLTRIIASLALVPLFLFVVYGGIPLYIAETAIVYIALHEFYKAF
                     KIKDVHPIFIIGYLFSIYLAVKNIFNLPLEYTYAVIFILFLASIIYMLMGKNNVIDVS
                     ITFLGVFYIGVFLDFIIITINGFEKGSIYVWLIFVISFMTDIFAYFSGYLLGKHKLIP
                     KVSPKKTIEGAIGGIIGSTLCCILFGYLFGIDLLQLAIIGSIGSVIAQLGDLFASSIK
                     RYVGIKDYGKIIPGHGGILDRFDSVILVAPFVYSAIKFFIR"
BASE COUNT         3166 a          790 c         1462 g         2278 t
ORIGIN      
        1 taatatccaa actaatacaa aatagtaata attgttttgt actggaggat atatatttat
       61 gaattgtaaa tggatatcta agatagatga gagaaaaaaa tgtcatagag aagcagattc
      121 ttctggatat tgtatctttc ataaagaaaa taagtctgat gaagagatac agttgatgat
      181 ggatactatt cataaagaag agataagtga atttaatgga tttgtttttg aaaatgaatt
      241 taatgcggaa gaaatattaa cttacaatta taaaatactg gatttttctg aatccatatt
      301 taaacaaaaa gcaaatttta aaaaatatat ttttaaaaag aatattattt ttaactatac
      361 agaatttaga gataaagttt tatttaatgg ttgtatattc ttagaaaact gtgattttaa
      421 tagaaccata tttagtaaaa actatataaa tgaccgtata tttgaaaaag tgaaatttaa
      481 aggacctgat ttggtagtta ataaagtaga aaattttcca cgaatggatg gaataatttt
      541 tagcatgtgt acaaaatttg tgttaaagaa tgttgaatat ggaaaaagtg agtatgagca
      601 tggcaagata aattatagaa tagctagaaa tcaagcaaca aaaattggag aatatgagat
      661 gataggattt tactattata aggaaagaat ttatagtagt aaaataatga aacgttctaa
      721 ttatcctact ttcagtgatt atttagttga aaaatttttt gaccaaatag cacgttacac
      781 aacaggttat ggagaaaagc catggaatat attattagtg attatagcaa taataagtgt
      841 ttttgcttta ttatacttat ttgtaggcat agaaagttca aatagcacac ttgtagcttt
      901 agatataaac aatataggtg attactcact aagtgagatt ttcaaaatgt atatggattt
      961 atggtatttt agcatggcta catttagtac agtaggatat ggagatatgg ttgctacaag
     1021 tttgattggg aaagcattgg caggtataga agtatttttt ggagttacaa taggagcaat
     1081 ttgggcatct gtgattatta aaagaatgat aaggtaatat ttgtgtaaat atggataggt
     1141 attaattact agatataaat tggaccaaat agggaaaatt taaatataaa tatacttaat
     1201 aatccaagaa ggtgaaaaat ttgaaaaatg cactaaaaaa aattatatca ttagccatga
     1261 ttctagtttt tataatacca aattattcat atgcagatgg taaatctgta gacaagtatt
     1321 caaaaacatc tatacttata gaccaagaaa caggtagagt tttatatagt aaagaacctg
     1381 atatgaaggt accattagct agtttaagta agatgatgac ttttttactt gcaatagaag
     1441 ctattgaaaa taaagaagta aaagaaactg ataaggtaaa aatagacaaa tctattgcat
     1501 cagtaaaagg gtcaagttat aaacttaaag atggtgaaga agtgccactt atagagctta
     1561 tgagaggtct tatgattgta tcaggaaatg atgcggcaat tgctatagca aaacatattt
     1621 gtaaaacgaa agaagcattt gtagatagaa tgaataaaaa agcaaaagaa ataggaatga
     1681 gtaatacaca ttttctaaat ccaaatggtc ttccaatata cgatttaagc aaccccaaaa
     1741 aaccagcaaa agaaaatatc tctactgcaa aagatatagc tattcttgga aaatacatgt
     1801 ttgaccatta tgaaaaacaa gtaacagcta taactgatat ggagacatat acaaattcag
     1861 atagaagttt tgaaaaaagc aatacaaatg cattattaag aattatacca gaagtagatg
     1921 gtataaaaac tggatatact ggcaatgctg gatattgctt atcattttct atggttgtaa
     1981 ataaaaatga gaaaaatgag aaaaaacgta gagtaatagg ggttgtatta ggtactaacc
     2041 ataaaaataa aagaacctct gcttcattag ctctactgaa atatggaaaa gaaaatttca
     2101 atatgaaaaa agtaattgat aaagatagct ttattggtaa gaaatatata aaaggaatga
     2161 aagagttaga ggttacatta aaagcaaaag atgaacttta tacaatatta aaagatgatg
     2221 aaagtataaa atcagaagtt aagattaaaa atatagagta ccctgttaaa aaaggtgata
     2281 ctatgggtgt tataaaatat tatactagtt caggtgactt acttggaagt gtagatatag
     2341 taagtaataa tagtatagat aacgtatcat taaaaacaaa attaaaaatg aaatttgcaa
     2401 attaaattca aaaaatggta taaaatacac aaaaaaatat aaaaatagaa aatatggaaa
     2461 aaatattgtt atttcttcgc ctctgtgata tactactaga ggtgaaaaaa taaaataaat
     2521 cacacacagc attgggatcc ttaaaaggtg cctattacat ggttttttag ggagaagatc
     2581 aagctggagg tataaaacca ggaggtaaga tatgtcagta atatcaatga aacaattatt
     2641 agaagcaggt gttcactttg gtcaccaaac aagaagatgg aaccctaaaa tggctaagta
     2701 tatattcaca gagagaaatg gaatatatat aatcgactta caaaaaacag ttaaaaaagt
     2761 tgaagaagct tacaagttca ctaaagaagt agctgaaaca ggaaagccaa tcttattcgt
     2821 aggaactaaa aaacaagctc aagatgcgat aaaagatgaa gctgaaagat gtggaatgta
     2881 ctttgttaat gaaagatggt taggtggaat gttaacaaac cacaaaacta taaaaacaag
     2941 aataaataaa ttaagagaat tagaaaaaat ggaagaagaa ggcgtattta atgttcttcc
     3001 taaaaaagaa gttataaaat taagagctga aaaagaaaaa ctagaaaaat acttaggtgg
     3061 aataaaagac atgcctgaat taccaggtgc aatgttcgta gttgacccaa gaaaagaaaa
     3121 catagctatt caagaagctc atagattagg tataccagta gttggtatag ttgatactaa
     3181 ctgtgaccca gaacaattag actttgctat accaggaaat gatgacgcta taagagccgt
     3241 aaaattaata actggtgcta tggcaacagc tgtaattgaa ggtagacaag gtgctgagga
     3301 agaagtagct gaagaccaag aataataatt tgacaattaa atggtaaggg tcgcccttac
     3361 catttataat atggaataga ataagtagga ggaaacttaa aaaatggcta atataactgc
     3421 tcaaatggta aaagagttaa gagaaagtac aggcgcagga atgatggact gcaagaaagc
     3481 tttacaagaa gctgaaggaa acatggaaaa agcagtagat ttattaagag aaaaaggatt
     3541 atcaaaagct gctaaaaaag ctggtagagt tgctgctgaa ggtctagttg caatagaaat
     3601 gaatgatgat aatacagttg cttctatggt agaagttaac tcagagacag atttcgttgc
     3661 taaaaacgaa gacttcaaag tgttcgttaa agatgctgct tgtatggcat tagctactga
     3721 taaagaagat atagcttctt tattaggtga aactcataaa gagggaataa ctttacaaga
     3781 agttttaaat aatagagttg caaaaatagg tgagaaatta gactttagaa gatttgctaa
     3841 agttgtaact aatggacaag ttgctggata cattcacggt ggtggaaaaa taggtgttct
     3901 tgttgaaatg gaaacagaag ctagagatgc taaagtttta gaattaggta aagatgtagc
     3961 tatgcaagtt gctgctatga atcctaagta tgtttcaaga gatgaagtag atgctgaata
     4021 catagcacat gaaacagaag tattaactca acaagcttta aatgaaggaa aaccagctaa
     4081 tatagttgaa aaaatggtta aaggaagatt agaaaaagaa ttaaaagagg tttgtttatt
     4141 agagcaaact ttcgttaaaa atccagatat aactgttaaa caattagttg ctgatgttgc
     4201 taaggcagta ggttctgata taaaagttgt taaagttgtg agattcgaag ttggtgaagg
     4261 tatacaaaag agagaagaaa actttgcaga agaagttgct aagcaactta agtaataacc
     4321 aaagagagaa cacgcaggtg ttctcttttt taaaaaatag aaaaaattgg atatgaagga
     4381 ttgaaatagg aggtttctga tggataaacc aatgtacaaa agggtattgt taaaattaag
     4441 tggagaagca ttagcaggag aaagaggttt tggtataaat aatgatgtag ttaatgatat
     4501 tgctattgct ataaaaaaaa tacaagaaat aggtgttgaa gtagctgtag tagtaggtgg
     4561 aggaaacttc tggagaggca gaaccagtga aggaatggat agaactactg ctgactatat
     4621 aggaatgtta gctacagtta tgaatgcaat ggcgctacag gatgcactag aaaatataga
     4681 tgttgctaca agagttcaaa ctgctataga catgagacaa attgcagaac catatataag
     4741 aagaagagca gttagacact tagaaaagga aagagttgtt atatttggtg caggaacagg
     4801 aaacccttac tttacaacag atacaactgc tgctttacgt gctgctgaga tggaagcaga
     4861 agttatattg ctagctaaaa atgttgatgc agtatatgac aaggatccaa aagtacatgc
     4921 agatgctaag aaatttacag aattaagtta catggaagtt atacagaaag aattaaaagt
     4981 aatggattct acagctacat ctttatgtat ggataataaa attccaataa aggtatttga
     5041 gcttacaaca gagaatataa taagagcagt aaaaggcgaa aatataggaa ctactgtaaa
     5101 ataatgaaga atgaaggagg agtaaaatta tgaaactgga aatacataag caattagaag
     5161 agaaaatgaa tgggacaatt gatgctttaa agtttgaatt tggaactata agagcaggaa
     5221 gagctaatgc acaaatgcta gacaaaataa gagttgatta ttatggaact ccaactccaa
     5281 taaatcaaat aggtgctata tctgtaccag aaccaagaat attaatgata tctccttggg
     5341 ataaatctgc tatgcatgaa atagaaaaag cgatagctaa ctcagactta ggattaaatc
     5401 catcaaacga tggtgaggtt ataagacttt ctgtacctgc tttaacagaa gaaagaagaa
     5461 aagaattagc taaaaaagct agtaaagctg cagaagaatt taaagttaga ataagaaatg
     5521 aaagaagaga cgccaatgag aaaattaaaa agatggaaaa aggcggagaa ttaactgaag
     5581 atgaattaaa aaaagcacaa gatgaagttc aaaaaatgac tgataaattt ataaaagaaa
     5641 tagatacatt attatctaaa aaagaaaagg acataatgga ggtataatat tgaaaaaata
     5701 ttataacctt ttaggtcttc atgtagatga ggtaaaacaa tattttgatg agcaaaatat
     5761 aaattatacc gtaaaatcta ttgaaggtaa aaaggataaa gaaaaacttg tagttcctag
     5821 agttataaaa atatctgaga taggtgatag tgtagaactg ataatcacat acttttctga
     5881 ctccttagtt taaggagtca gaacaatatt ggaggcaaaa tatgaataac aacattatat
     5941 atgatataga cttaaataac atacctactc atattgctat tataatggat ggaaatggaa
     6001 gatgggcaaa agctagattt cttccaagaa ctgcaggaca taaggctgga gtagaaacta
     6061 taagagatat agtaaaagaa tgctcaaaat taggtgttaa gcacttaaca ttatatgcat
     6121 tttcaacaga aaactggaaa agaccgaaac ttgaagttga cacacttatg aacttattat
     6181 ctacatactt aagaaatgaa atagctgaac ttcaccaaaa caatgtaaaa gtaactgcta
     6241 taggagatat aagtgcttta ccaaaaactt gtataagaga attaaactca gctaaggaac
     6301 tgacaaaaaa caatacagga gttaacttaa atttagcatt aaactacgga agtagagcag
     6361 atataaaaaa tgctcttata gatatagtaa aaaattgtga aagtggtaaa atagatataa
     6421 acaatattga tgaagatatt ataaaaaact atttaagcac aaagtctata ccagatccag
     6481 acttggtaat aagaacaagt ggtgaacaaa gattgagtaa ctttttactt tgggaagttg
     6541 cttattctga gttttacttt actgatatac attggcctga ttttaaaaaa gaagaactac
     6601 agaaggctat atacgtatat caaagaaggg atagaagatt tggaggactt aagtaaggag
     6661 attattttat gcttacaaga attattgctt cactagctct ggttccatta tttctatttg
     6721 ttgtatatgg aggtattcct ctatatatag ctgagacagc aatagtttat attgcattgc
     6781 atgagtttta taaggcattt aaaataaaag atgtacatcc aatattcatt ataggatatt
     6841 tattttctat ttatttagct gtaaaaaata tttttaattt accattagaa tatacttatg
     6901 cagtaatttt tattttattt ttagcaagta taatttatat gttgatgggc aaaaacaatg
     6961 ttatagatgt ttcgattacg tttttaggag ttttttatat aggagtattt ttagatttta
     7021 taattataac tataaatgga tttgaaaaag gtagtatata tgtatggctt atatttgtga
     7081 tatcttttat gacagatata tttgcatatt ttagtggtta tttacttgga aaacataagc
     7141 taattcctaa agttagtcct aaaaagacta tagaaggagc tattggagga ataataggaa
     7201 gtacactttg ttgtatttta tttggatatt tatttggcat tgatttgctt caattagcga
     7261 taataggaag tataggaagt gtaatagctc aattaggaga tttatttgca tcttctataa
     7321 agagatatgt agggataaag gattatggaa agataatacc tggtcatggg ggtatattag
     7381 atagatttga tagtgttata ttagttgcac cttttgtata tagtgcgatt aaatttttta
     7441 ttagataaag attggttgga tttaaaagag caatctataa ttgctagtaa tgaaaatagc
     7501 tatgtaactt ttaaatgcag agatattctg cagttattag ttacatggct attttcattg
     7561 ttcaaaaatt tagaagacct tggggaattt tataagaata agtattactt tataatagta
     7621 tactatattt gtagtgagta tattttttat actataacta tcattaaaaa atattttttt
     7681 gtttaataat ttcgat
//
LOCUS       DAMJYN010000134         7517 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.140, whole genome shotgun sequence.
ACCESSION   DAMJYN010000134 DAMJYN010000000
VERSION     DAMJYN010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7517)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7517)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7517
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.140"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            137..1114
                     /locus_tag="PC466_003417"
     CDS             137..1114
                     /locus_tag="PC466_003417"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HDF2770769.1"
                     /translation="MRDKIIEIILNNKSEFISGEELSKQLGVSRAAIWKHMKALKEEG
                     YNIESVNKKGYRLAENPTDLLSPQNIYYKLDTEFIGKNIEHLDTIDSTNEHAKRIAIN
                     SVDGTVILSEHQDMGKGRLGRRWDSKTHEGIWMSIILKPDMEPFKAPFITLIAGASVT
                     KALNNLGANTLIKWPNDVILNGKKICGILTELSAEIERTNYVVLGIGINVKIMDFEQE
                     IADKATSLYKEGYMLSRVDIVRNVLTEFEKLYLDYTVNNSKEKTLKICRDYSAIIDKN
                     IYVLKGDNRELVKCLDINEEGNLLVQRSDGSIKEIISGEVSIRGEKGYV"
     gene            1107..2075
                     /locus_tag="PC466_003418"
     CDS             1107..2075
                     /locus_tag="PC466_003418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P1 family peptidase"
                     /protein_id="HDF2770770.1"
                     /translation="MYNNILDIEGLKVGQVEDRNGLTGCTVVICEEGATCGVDVRGSA
                     PGTRETDLLDPVNMVQKVHAVVLAGGSAYGLESTCGVSRYLEEKGIGFDVGVGKVPIV
                     VGAVLFDLGVGSFKCRPDLKMGYRACEVANTDILNQGNYGAGCGATVGKIRGQEYAMK
                     GGIGSYSIKLDNGLIVSALIAVNALGDVYENGKVIAGALNDKKTETIDTYKLMKQGES
                     KGGFSVDNTTIGIIATNAKLTKAGCKKISQMGHDGYAKSIFPIHTPHDGDTIFTISTG
                     EIEADITLVGSLAVEVVEKSIINAVKKADSVENIMAYKDIVKKREI"
     gene            2259..2849
                     /locus_tag="PC466_003419"
     CDS             2259..2849
                     /locus_tag="PC466_003419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HDF2770771.1"
                     /translation="MMNTSASVRKVNVRKMTIIGVLSAISIMLSMTPLGFIPVGPTKA
                     TIMHIPVIIGAIMEGPIVGAAIGFIFGISSLLNAITNPTVTSFVFINPLVSILPRVMI
                     GVLAYYVYQLIIKATNKVYISGLITGAIGSLLNTAGVLGMIYVLYADKYLHAMGKSGS
                     AGKVIMALAAANGVPEAIVGALVVAAVATVLKKSKK"
     gene            2868..3638
                     /locus_tag="PC466_003420"
     CDS             2868..3638
                     /locus_tag="PC466_003420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III pantothenate kinase"
                     /protein_id="HDF2770772.1"
                     /translation="MLLVFDVGNTNMVLGIYKGDKLVNYWRIKTDREKTSDEYGILIS
                     NLFDYDNVNISDIDDVIISSVVPNVMHSLENFCIKYCKKQPLIVGPGIKTGLNIKYDN
                     PKQVGADRIVNAVAGIEKYGAPSILVDFGTATTFCAISEKGEYLGGTIAPGIKISSEA
                     LFQSASKLPRVELAKPGMTICKSTVSAMQSGIIYGYVGLVDKIISMMKKELNCDDVKV
                     IATGGLAKLIASETKSIDYVDGFLTLEGLRIIYEKNQE"
     gene            3775..4743
                     /gene="dusB"
                     /locus_tag="PC466_003421"
     CDS             3775..4743
                     /gene="dusB"
                     /locus_tag="PC466_003421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HDF2770773.1"
                     /translation="MKIGNLELKNKVFLSPMAGVTDLPFRLICKEQGCGLLYTEMING
                     KALCYDDENTKKMLKIEEEEHPVAVQIFGSEPEFMGRAAEIMNDYSNEILDINMGCPA
                     PKVVKNGDGSALMKNPKLAEEVLRAVVKNSKKPVTLKIRKGWDDNSVNAVEIAKIAED
                     CGISALAIHGRTREQFYTGKADWDIIAEIKKNLSIPVIGNGDVFTIEDSINMLDKTGC
                     DAIMIGRGAQGNPWIFKRINHYMNTGEILPEPTLNEKISTAIKHLKLAVEEHGEYVAV
                     REMRKHIAWYLKGLRNSAKLRDEINKIEDYQEVVSKLEYYMEDSLT"
     gene            4852..5331
                     /gene="greA"
                     /locus_tag="PC466_003422"
     CDS             4852..5331
                     /gene="greA"
                     /locus_tag="PC466_003422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003514606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HDF2770774.1"
                     /translation="MEENKEFLLTQEGYDKLEEELENLKVVKRKEVAERIKVAISFGD
                     LSENAEYDEAKKEQAQVEERILKLENMVRKAVIIDESKIDLNVVTIGSIVKVKDLEFD
                     EEVEYTIVGSTEADPYDGKISNESPVGKALLGRAAKEVVEVQVPDGVAKFEILEIRR"
     gene            5346..6875
                     /gene="lysS"
                     /locus_tag="PC466_003423"
     CDS             5346..6875
                     /gene="lysS"
                     /locus_tag="PC466_003423"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HDF2770775.1"
                     /translation="MKNNQQSNEEAQIQEDLSEVLQVRRDKLKKLQESGRDPFKESRY
                     DRTHYSMDIKDNFDSLEGKTTKIAGRIMSKRIQGKAGFIDIQDQEGRIQSYVRLDAIG
                     EEEYSVFSTYDIGDIVGIEGEIFKTKKGEISVKAKSVVLLCKSLQVLPEKYHGLKDQE
                     LRYRQRYVDLIVNPEVKNAFLIRTKALKALRAYLDDRGFLEVETPILNTIAGGANARP
                     FITNHNTLHIPMYLRIANELYLKRLIVGGFDKVYEMGRMFRNEGMDLKHNPEYTAIEL
                     YQAYADYTDMMEITENVIAHMAEVATGSMIVNYQGTEINFTPPWKRMSMEDCVKEYSG
                     VDFSTINTDEEALEVAREKGIEIKPGMRRGEVINAFFEEFGEDKLIQPTFITHHPVEV
                     SPLSKRNVEDPRRTDRFEAFANKWELANAFSELNDPIDQKGRFIDQLRKRELGDDEAF
                     EMDEDFLKALEVGLPPTGGLGIGIDRVIMLLTNSPSIRDVLLFPTMKPIDNNPNKEEE
                     N"
     gene            7184..7378
                     /locus_tag="PC466_003424"
     CDS             7184..7378
                     /locus_tag="PC466_003424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770776.1"
                     /translation="MFQVINFLCLFCVGFLVLDVMIYFCKDAMDIFEGTTNVNKVKSI
                     NIWADRVRANSYSYENKIAK"
BASE COUNT         3009 a          756 c         1512 g         2240 t
ORIGIN      
        1 atataaaata taaaacaacc attataataa ttaaaaagga aatttaaaat taatagtatt
       61 aaaagtatat taataatgta taattattta ttagaagaaa ataagtcatg aaattatgtc
      121 atattagagg tgaaatatgc gagataaaat aatagagatt atattaaata ataaatctga
      181 atttatttca ggagaagaat tatcaaaaca attaggggtg tcacgtgcag ctatatggaa
      241 acatatgaaa gccttaaaag aagagggata taatatagaa tctgtaaata aaaaagggta
      301 tcgattagcg gaaaatccaa ctgatttatt aagcccacag aatatttact ataaattaga
      361 tacagagttt attggaaaaa atattgaaca tcttgacact atagattcaa caaatgaaca
      421 tgctaaaagg atagctataa atagtgtaga tgggactgtg attttaagtg aacatcaaga
      481 tatggggaaa ggacgattgg gaagaagatg ggattcaaaa actcatgaag gaatctggat
      541 gagtattata ttaaaaccag atatggaacc attcaaagct ccatttataa ctttaatagc
      601 aggagcaagt gtaacgaaag ctttaaacaa tctaggagca aatacattaa taaaatggcc
      661 aaatgatgtt attttaaatg gaaaaaaaat atgtggtata ttaacagagt tatctgctga
      721 aattgaaaga acaaattatg ttgttcttgg aattggaata aatgttaaaa taatggattt
      781 tgaacaagaa atagctgaca aagccacatc attgtataaa gaagggtata tgttatccag
      841 agtagatatt gttaggaatg tattgactga atttgaaaaa ttatatttag attatactgt
      901 aaataattcc aaagaaaaaa ccttaaaaat atgtagagat tattctgcaa ttatagataa
      961 aaatatatat gtattaaaag gagataatag agaactagtg aaatgtttag acataaatga
     1021 agagggaaat ttattagttc aaagaagtga tggaagtata aaagaaatta tttcaggtga
     1081 agtttctata agaggagaaa aaggatatgt ataataatat tttggatata gaaggcttaa
     1141 aggttgggca ggttgaggat agaaatggtc ttactgggtg cacagtagta atatgtgaag
     1201 aaggagctac ttgcggtgtt gatgtaaggg gttctgctcc agggactaga gaaaccgatt
     1261 tattagaccc tgtaaatatg gttcaaaaag ttcatgcagt agttttggct ggaggttctg
     1321 catatggtct tgaatccact tgtggtgtaa gtagatactt agaagaaaaa ggaattggct
     1381 ttgatgtagg tgtaggtaaa gtgcctatag ttgtaggagc agttttattt gatttaggag
     1441 tagggagctt taaatgtaga ccagatttaa agatgggtta tagagcttgt gaagttgcaa
     1501 atactgatat tttaaatcaa ggaaattatg gagcaggttg tggagccact gttggaaaaa
     1561 taagaggtca ggaatatgct atgaaaggcg gaataggtag ctattctata aaattagata
     1621 atggtctaat tgtatctgca ttaattgctg taaatgctct tggagatgtt tatgaaaatg
     1681 gtaaggttat agctggtgct ttaaatgata aaaagacaga aacaattgat acatataaat
     1741 taatgaaaca aggtgaaagt aaaggtggat ttagtgtaga taatactaca attgggataa
     1801 ttgcaacaaa tgctaagtta accaaagctg gatgtaaaaa gatatctcaa atgggacatg
     1861 atggatatgc taagtctatt tttcctatcc atacacctca tgatggagat acaatattca
     1921 caatatcaac aggagaaata gaagcagata taacattagt aggttcattg gctgtagagg
     1981 ttgtggaaaa aagtataata aatgcagtaa aaaaagcgga tagtgtagaa aatataatgg
     2041 catataaaga tatagtaaaa aaacgagaaa tatgatgaaa ttagcatatt tttcttgtca
     2101 aattgttgac aatggcaact catcttgata aaattattct tgttagagcg ggcatcctac
     2161 aatggtagct tgactcatag ttataagaaa aaaacgaaaa aaattaaaaa attaagtagt
     2221 ccggcatctt aatgagctgg aacggaggtg tattttttat gatgaacaca agtgcatcag
     2281 taagaaaagt aaatgtaaga aagatgacta taataggagt actatcagct atttctatta
     2341 tgctatctat gactccattg ggatttattc cagttggacc tacaaaagca actataatgc
     2401 acataccagt tattattgga gctattatgg aaggaccaat agttggggca gcaataggat
     2461 ttatatttgg gatatcaagt ctcttaaatg ctataacaaa cccaacagta acatcttttg
     2521 tttttataaa tccattagtt tcaatattac caagagttat gataggtgta ttagcttatt
     2581 atgtatatca gttaataatt aaggctacaa ataaggtata catatcaggt ttaattacag
     2641 gggcaatagg ttctctgtta aatacagctg gagttttagg aatgatatat gtcttatatg
     2701 ctgacaagta tcttcatgca atgggtaaaa gtggttcagc aggaaaagta ataatggctc
     2761 ttgccgcagc aaatggggtg ccagaagcaa tagtaggggc tttagtagta gctgctgttg
     2821 ccactgtact taagaaaagc aaaaaataga aagaaggtta atgacatatg cttctagtat
     2881 ttgatgttgg aaatactaat atggttttag gtatatataa aggtgacaaa ttagttaatt
     2941 actggagaat taaaacagat agggaaaaaa cgtctgatga atatggaatc ctgataagta
     3001 acctatttga ttatgataat gtgaatataa gtgatattga tgatgttata atatcatctg
     3061 tagttccaaa tgtcatgcat tctcttgaaa acttttgtat aaagtactgt aaaaaacagc
     3121 cattaatagt aggtccaggc ataaaaacag gtctaaatat aaaatatgat aatccaaaac
     3181 aagttggggc agatagaata gttaatgctg tagcagggat agaaaagtat ggagcaccaa
     3241 gtatacttgt tgattttgga acagcaacta cattttgtgc tatctctgaa aaaggtgaat
     3301 atttgggtgg aacaatagca ccaggaataa aaatatctag tgaggcgtta tttcaaagtg
     3361 cgtctaaatt acctagagta gaattagcta agccaggtat gactatttgt aagagtactg
     3421 tatcagccat gcaatctgga ataatttatg gatatgttgg tttagttgac aaaataataa
     3481 gtatgatgaa gaaagaattg aattgtgatg atgttaaggt tatagctaca ggtggattag
     3541 ctaaactgat tgcttcagag acgaaaagta tagattatgt agatggtttt ttaacactag
     3601 aaggattgag aataatatat gaaaaaaacc aagaataatt aatatacagg gaattgggtt
     3661 atatatccaa ttcccttttt atgatagatt tctagctata tgtggtatat tataatgagg
     3721 aaataagaat ttaaagttaa atcacaaaat aaaggcaaaa ataggagaaa aacaatgaaa
     3781 ataggaaatt tagaattgaa aaataaagtt tttctatcac ctatggcagg tgtaacagac
     3841 cttccattta gattaatttg taaagaacag ggatgtgggc ttttatatac agaaatgata
     3901 aatggtaagg cactttgcta tgatgatgaa aatactaaaa aaatgcttaa gatagaagag
     3961 gaagaacatc ctgtagcagt tcagatattc ggttcagaac cagagtttat gggaagagca
     4021 gcagagataa tgaatgatta ttcaaatgag attctcgata taaatatggg gtgtccagct
     4081 ccaaaagtag ttaaaaatgg agatggttca gcacttatga aaaatcctaa gcttgcagaa
     4141 gaggtattga gggcagtagt gaagaactca aaaaagccag tgactttaaa gattcgaaaa
     4201 ggctgggatg ataatagtgt aaatgctgtt gaaatagcaa agatagcaga ggattgtgga
     4261 ataagcgctt tagcaataca tggaagaact agagaacagt tttatacagg caaagcagac
     4321 tgggatataa ttgcagagat taagaaaaat ttgagtatac ctgttatagg aaatggtgat
     4381 gtatttacaa tagaagattc aataaatatg ttagacaaaa ctggttgtga tgctataatg
     4441 ataggtaggg gtgctcaagg taacccttgg atatttaaaa gaataaacca ttatatgaat
     4501 acaggcgaga ttttgccaga gccaactctt aacgaaaaaa taagtactgc cattaagcat
     4561 ttaaaacttg cagtagaaga acatggagag tatgtagctg taagggaaat gagaaaacac
     4621 atcgcttggt atttaaaagg acttagaaac tctgcaaaat taagggatga aattaacaaa
     4681 atagaagact atcaagaagt tgtgtcgaaa ttggagtact atatggaaga ctccttgaca
     4741 taaaaataat agtgacttat aatatagcgc ataaattaaa aaaagattat aaaattttta
     4801 aaatataatt aggaaaattc ctaagaaatt tgtgaaggag ttgtatttat aatggaagaa
     4861 aataaagagt ttttattgac acaagaggga tatgataaat tagaagaaga attagaaaac
     4921 ttaaaggttg taaagagaaa agaagttgca gagagaataa aagttgctat atcttttggt
     4981 gatttatctg aaaatgctga gtatgatgaa gctaaaaagg aacaagcaca agttgaagaa
     5041 agaattttaa aattagaaaa tatggttaga aaagctgtta tcatagatga aagcaaaata
     5101 gaccttaatg ttgttacaat aggatcaata gttaaagtta aggatttaga atttgatgaa
     5161 gaggttgaat atactatagt tggttcgaca gaagcagacc catatgatgg taaaatatca
     5221 aacgaatctc ctgtagggaa agcactttta ggtagagctg cgaaagaagt tgtggaagtg
     5281 caagttcctg atggagttgc taagtttgaa atattagaaa taagaagata atttggagga
     5341 aaaaaatgaa aaataatcaa caaagcaatg aagaagcgca aattcaagaa gaccttagtg
     5401 aagtacttca agtaagaaga gataaactaa aaaaattaca agagtcaggt agagatcctt
     5461 ttaaagaaag tagatatgat agaactcatt attctatgga tataaaagat aactttgatt
     5521 ctcttgaagg taaaactaca aaaatagcag gacgtataat gagcaagaga atacaaggga
     5581 aagctggctt tatagatatt caagaccaag agggaagaat ccaatcttat gtaagactag
     5641 atgctatagg agaggaagaa tatagtgtat tttcaacata tgatattgga gatatagttg
     5701 gaattgaagg agaaatcttt aaaactaaaa aaggtgaaat atctgtaaag gctaaatctg
     5761 tagtattact atgtaaatct ttacaagttt taccagaaaa atatcatgga ttaaaagacc
     5821 aagaactaag atatagacaa agatatgttg acttaatagt aaatccagaa gtaaaaaatg
     5881 cttttttaat tagaacaaaa gcattaaaag cattaagagc atacttagat gatagaggat
     5941 ttttagaagt tgagactcca atattaaata ctatagcagg tggggcaaat gctagaccat
     6001 ttataactaa tcataatact ttacatatac caatgtattt aagaatagca aatgaattgt
     6061 atttaaaaag acttattgtt ggtggatttg ataaagttta tgaaatggga agaatgttta
     6121 gaaatgaagg tatggattta aaacataatc ctgaatatac tgcaatagaa ttatatcaag
     6181 catatgcaga ctatactgat atgatggaaa taacagaaaa tgttattgca catatggctg
     6241 aagttgctac aggaagtatg atagttaact atcaaggaac agaaataaac tttacaccac
     6301 cttggaaaag aatgagtatg gaagattgtg ttaaagaata ttctggtgta gatttttcta
     6361 ctataaatac agatgaagag gcactagaag ttgctagaga aaaaggtata gagataaaac
     6421 ctggaatgag aagaggagaa gtaataaatg ctttctttga agaatttgga gaagataaat
     6481 taatccaacc aacatttata actcatcatc cagttgaagt atctccatta tctaagagaa
     6541 atgttgaaga cccaagaaga actgatagat ttgaggcatt tgctaataag tgggagttag
     6601 ctaatgcatt ttctgaactt aatgacccta ttgaccaaaa aggaagattt atagaccaat
     6661 tgagaaaaag agaattaggt gatgatgaag cttttgaaat ggatgaagat ttcttaaaag
     6721 cattagaggt aggtctacct cctacaggag gactaggaat aggtatagat agagtaatta
     6781 tgttattaac taactctcca tctataagag atgtattatt attcccgact atgaaaccta
     6841 ttgataacaa tccaaataaa gaagaagaaa actaagaaat attagcattc tactaagttt
     6901 taaataaagt ttagctatta aattagcaat aaatagctaa attttgttta aaatgtcagt
     6961 gtagaatgct ttttatatgc ttcaaagatt cttttagata tttaatttat aaattaccaa
     7021 caaacgttag aaattgatat tagtttttgt tgattgagac tttatattta gaaaatatga
     7081 ttgaaagtaa tttattatga aaatatttag aataatttat gagaaggtaa aaagaataat
     7141 ttatgagaat actatatata aaaaattatt gggggaatgt ctgatgtttc aagtaattaa
     7201 ttttttatgt ttattttgtg ttggattttt ggttcttgat gttatgatat atttttgtaa
     7261 ggatgcaatg gatatttttg agggtacaac taatgttaat aaagttaaga gtataaatat
     7321 ttgggcagat agagtgagag ctaattcata ttcttatgaa aataaaattg caaaataggt
     7381 aaaattatat atgcatgtat tgtttgtaat atcaagggtt atatctatta gttttaatta
     7441 tatttattaa aaaaaccaaa agttataacc ttttttaaaa taaaaaacaa aaaaagtatt
     7501 gacgaaatat ttttaag
//
LOCUS       DAMJYN010000135         7458 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.141, whole genome shotgun sequence.
ACCESSION   DAMJYN010000135 DAMJYN010000000
VERSION     DAMJYN010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7458)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7458)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7458
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.141"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            479..1171
                     /locus_tag="PC466_003425"
     CDS             479..1171
                     /locus_tag="PC466_003425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2770777.1"
                     /translation="MYNILVVDDDKEIVDSIEIYLKSEGFKIYKAYDGMKALEIITEN
                     DIHLILMDIMMPKLDGIKATVKIREERNIPIILISAKSEDTDKIIGLNIGADDYITKP
                     FNLLELIARVKSNLRRYVTLGNYEDTCKEILKSGALELNTLTKEVKIDGENIKMTPIE
                     YKIIELLLENKGRVFSIDEIYEKVWNEESFNSENTVAVHIRRIREKIEINPKEPRFLK
                     VVWGVGYKIEKF"
     gene            1367..3427
                     /locus_tag="PC466_003426"
     CDS             1367..3427
                     /locus_tag="PC466_003426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HDF2770778.1"
                     /translation="MEKYRALKLVSLIIISISFPLTILLATIGLAEPKYNIQKTSTKS
                     GIFNISNDFYDSNIFDEGTVESLLSNFKISVDSQLTSEEKSKLQTKSKSIDLSSNDSE
                     YDKIMINKQASEEYLSYLKNIKVYVINTYTGVFYTNTSYGNLDDFKQKTKSYCNIEII
                     NNVGKSSYIKTINGEKFELNNLSMELNGVDEAFEAYVSFPEEPTIEDGIVYTNFQIFK
                     QATEKVRLFFVACLSLAIVCLLSIILYSRIKGEVLKRNNVFLLIYSKIPMEFNVILVF
                     ISIAILTMYALAVSYHIDVIVLVSLSLLIVSNNIFFINVQLSYLENKMCIFKTSIIVR
                     VILWLIKTVREVSNAIKKVSLARKVIVIVIISLALIMVISTRSIGMGLLFSICIFLGF
                     TIYITKRLSYLSYVIEGTERIKKGELDYKIKITGNDNFTSLAENINNIGEGLDRAIEE
                     QVKSERMKSDLITNVSHDLKTPLTSIINYVDLIKKEESIQPEYINDYIKVLESKSKRL
                     KLLIEDLFEASRVSSGNIELQISKIDLVQLLRQSIGELEEKLSKNNLYLKLNVPNDKV
                     YIWADGRRMYRVFENLLSNIAKYSLEETRVYIDVYDYGENVKVTMKNISSYELNFDPS
                     EIMERFKRADESRNTEGSGLGLAIARDLVALQGGKFYIEIDGDLFKANLEFQKYEEEI
                     TNME"
     gene            complement(3633..3956)
                     /locus_tag="PC466_003427"
     CDS             complement(3633..3956)
                     /locus_tag="PC466_003427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HDF2770779.1"
                     /translation="MNNNYIFFIIIGMYIVTYLPRVLPMLIFSKKEMPDFLKKIMKFI
                     PVAILTSLTAKDVFFNGDSLYLSIANPKIISFMIVLLVAYKFKSIGISIITGVISIYL
                     FGIIL"
     gene            complement(3949..4650)
                     /locus_tag="PC466_003428"
     CDS             complement(3949..4650)
                     /locus_tag="PC466_003428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HDF2770780.1"
                     /translation="MERTQQLKESFIASIPIFLGYIPIGIVGGILLQKSGLSPFQIAL
                     MVTLVFGGSSQFIAASMISTGASVTSIVLTTFIVNLRHFLMSSNLNMYIKNKSPKFIL
                     PFCHTITDETFAVNYEKFTAGNWSDRNAIYLNFFCLISSVLANFIGAFLGESISIDSS
                     ISGFILTSMFIALIVSQIKNKIYIVVFISSIIISVILYALFKSNLVIIVASILASLIG
                     FFIEESYCKKEESYE"
     gene            complement(4928..6313)
                     /locus_tag="PC466_003429"
     CDS             complement(4928..6313)
                     /locus_tag="PC466_003429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HDF2770781.1"
                     /translation="MPINSFENYPMNWKPKRPSKGQILYKALAEQLEQDINNGFLLPG
                     TKLPPQRELADFLDVNVSTISRAFKICEKKGLISGVTGSGTFVSYDTRSNLFLMSSNN
                     KITFIEMGTMNPDFTLEEMNTLFKHIIKEIDFKTIFQYGQRDGAKWQKEAIAKLIYKA
                     GLETTSDSLLPASGGQNAIVAILAGLFQHGDRIGVDPLTYPGIKTAAKMLGIQLIPIK
                     QEDNEISEEGLLYACKNENIKGLYIIPDYQNPTTHIMSQNGRKMIANIASKYNLIVIE
                     DAIHSLLNETHLNPVASYLPNQTIYITSLSKIIAPSLRLAYISTPKQYREALSSALYN
                     INLSQSYFLTEIAYRMITSGEADKLINARRKSARRRNKIINQYLSGYNLLGNEECIFR
                     WLILPDGIMAEKFEIQALKEGVQVYASERFAVGKEKPISAIRIAVCATESTEELKAGL
                     SVLKRLLEEKK"
     gene            complement(6421..>7458)
                     /locus_tag="PC466_003430"
     CDS             complement(6421..>7458)
                     /locus_tag="PC466_003430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HDF2770782.1"
                     /translation="YKHNLDNYIPYDQGITLDIFMYIWILGIIAISFYYLRTNFKFYN
                     YIENFKKEILEIDITSILDEQAKELSINKKLQIYKVKGIYSPAIIGLTRCKIIIPEKK
                     YNNKELRFIFKHELIHYKRKDNLFKLLISIICIIHWFNPILYLLKKYFHELCELSCDE
                     IVIDKCTTSEIKEYAYIILNTIKYQKTLKYSSFVSQFLNKKNIILKKRLNSMFNQDKK
                     KINLGLKFLLTFIIIGSIFSINSNFKQNEDVEYTIAKINYNKNGETYGTHIIDSNGNS
                     IEPELIQTIGRGKKVGYVKKRDLYDCDNQPKTPEEAVLYTRKRNFNIFKKTIPLYDKE
                     GIKIIGRFEIN"
BASE COUNT         2874 a          845 c         1047 g         2692 t
ORIGIN      
        1 atagaatatg tacagtatat agtagataga atgtataaaa atagaattta aataagtagc
       61 tattattgca gtgaaataaa tgtttctaag tatatttggg tggaagaatg gtggaagaaa
      121 attagtgaaa tgtaattctt ccaccattct tccaccccaa aaataaaaac tgttcaataa
      181 gaattaatat acattaattc agctgaatcc aatcaaaata cttaaataaa agtaatctga
      241 aaataacata attcaaatca atttattcaa ataaatctca atttatctta aatcttaaga
      301 aatatttaag aattaggata atattttctt aagatttata ttttattata tagttataag
      361 ggaaagttac aaaaatgtaa gccaaagtaa tataacaatt tagtcattgt tgagaaagta
      421 agtgaaagat attgtataat atagataagt attattatac aatagaggaa gtgaaaatat
      481 gtacaatata ttagtagtag acgatgataa agaaattgtt gattcaatag aaatatatct
      541 taaatcagaa ggatttaaaa tatataaagc atatgatgga atgaaagctt tggaaataat
      601 aacagagaat gacattcatc taatactaat ggatataatg atgcctaaat tagatggaat
      661 caaagcaact gtaaaaatac gagaagaaag aaatattcca ataattttaa tttcagcaaa
      721 aagtgaagat acagataaaa taataggatt aaatattgga gctgatgatt atataacaaa
      781 gccatttaat ctattagagc ttatagctag ggttaaatca aacttaagac gatatgtaac
      841 tttaggtaat tatgaagata catgtaaaga aattttaaaa agtggagctt tggagttaaa
      901 tacactaaca aaagaagtta aaattgatgg tgaaaacata aaaatgaccc caattgagta
      961 taaaataatt gaacttcttt tagaaaataa aggacgagtt ttctcaatag atgagatata
     1021 cgaaaaagta tggaatgagg aaagttttaa ttcagaaaat acagtagcag tacatatcag
     1081 acgaataaga gaaaagattg aaataaatcc aaaagaacca agatttttaa aggtggtgtg
     1141 gggagttggt tataagattg aaaaatttta gtggaaaaat tataaaagaa aagagtttaa
     1201 tatttaattg cattttgatt ttagtcattt ttacatttac acaaatgtta ggaattttaa
     1261 tatgttttaa ttttttctct gagagtttaa tttactctat ggggattatg cttttcttaa
     1321 actttatttt atataaaata ctgacaatgt agatgaggtg ggcaacttgg aaaaatatag
     1381 agcattaaaa ttagtttcat taatcataat atctatctca tttccattaa ctatattgtt
     1441 ggctacaata ggacttgctg agcctaaata caatatacaa aaaacttcta caaagagtgg
     1501 gatttttaat atatctaatg atttttatga tagtaatata tttgatgaag gaacagtgga
     1561 aagcttatta tctaatttta agatatctgt ggatagtcag ttaactagtg aagaaaaaag
     1621 taaactccaa acaaaaagta aaagtataga tttaagtagt aatgattctg agtatgataa
     1681 aatcatgatt aataaacaag cttctgaaga atatttaagt tatctaaaaa atataaaagt
     1741 gtatgttatt aatacatata caggagtatt ttatacaaat acatcatatg gtaatttaga
     1801 tgattttaaa caaaaaacta agagctattg taatatagag ataataaata atgtaggaaa
     1861 gagctcgtat attaaaacaa taaatggaga aaaatttgaa ctgaataatc tgagtatgga
     1921 actaaatgga gtagatgaag cctttgaggc atatgtctct tttccagaag agccaactat
     1981 agaagatgga atagtataca ctaattttca aatatttaaa caagctacag aaaaagtaag
     2041 attatttttt gtagcttgtt taagtttagc aattgtgtgt ttattatcta tcattttata
     2101 tagcagaata aaaggtgaag ttttaaaaag aaataatgta tttttactaa tatacagtaa
     2161 gatacctatg gaatttaatg taatactagt atttatttca attgcaattt taactatgta
     2221 tgctcttgct gtatcttatc atattgatgt aattgtatta gtttctttat ctttactgat
     2281 agtatcaaat aatatatttt ttataaatgt gcaattgagt tatttagaaa ataaaatgtg
     2341 tatatttaag acaagtatta tagtaagagt gattttatgg ttaataaaaa ctgtaaggga
     2401 ggtcagtaac gctataaaga aagtatcttt agcaaggaaa gttattgtta tagtgataat
     2461 atctttagct ttaatcatgg taattagcac tcgaagtata ggtatgggat tactgttttc
     2521 tatatgtatt tttttaggat ttacaatata tataactaaa agactttcat atcttagtta
     2581 cgtaatagaa ggtacagaaa gaataaaaaa gggagaatta gattataaga taaaaattac
     2641 tgggaatgat aattttacgt ctttagctga aaatataaat aatattggag aaggtcttga
     2701 tagagctata gaagagcaag taaaaagtga aagaatgaag tctgatctta taacaaatgt
     2761 atctcatgat ttgaaaactc cacttacttc tataataaat tatgtagatt taattaaaaa
     2821 agaagaatca atacaaccag agtatataaa tgattatata aaggtacttg agtcaaagtc
     2881 aaaaagacta aaattattga tagaagattt atttgaagcg agtagagtaa gtagtggcaa
     2941 tatagaatta caaattagca agattgattt agtgcaacta ttaagacaaa gcataggtga
     3001 acttgaagaa aaattatcta aaaataattt atatttaaaa ttaaatgttc caaatgataa
     3061 ggtgtatata tgggcagatg gaagaagaat gtatagagta tttgaaaatc ttttatctaa
     3121 tatagcaaaa tattccttag aagaaactag agtctatatt gatgtatatg actatggtga
     3181 aaatgtaaag gtaactatga aaaatatatc ttcttatgaa ttaaattttg acccaagtga
     3241 gattatggaa agatttaaaa gagctgatga atcaaggaat actgaaggaa gtggattagg
     3301 gcttgctatt gcaagagatt tagtagcttt acaaggtgga aaattttata tagaaataga
     3361 tggagattta tttaaagcaa atttagagtt tcaaaaatat gaagaagaaa taacaaatat
     3421 ggaatgagat agtatttaag tatatatatt ttttttactg tcgaaagctt ttattataat
     3481 atattagaat atttacagta gagaatgaag agtaaaaaca gagtaacttt aagtcactct
     3541 gttttttatt taaaatcaat aatataacaa cttaaattaa aattgtacac atagttttaa
     3601 aataacttat acaataaaac attatccaaa tatcacaaga taattccaaa taaatatata
     3661 gatatcactc ctgtaataat agaaatacca atagatttaa acttatatgc aacaagaagt
     3721 acaatcataa aagatataat tttagggtta gctatagata aatatagact atctccatta
     3781 aaaaatacat ctttagcagt taaggaagta agtattgcta caggtataaa tttcatgatt
     3841 tttttcaaaa aatcaggcat ctcttttttt gaaaaaatta acataggaag cactcttggt
     3901 agatatgtaa caatgtacat tccaattata ataaaaaata tataattatt attcataaga
     3961 ttcctccttt ttacagtaag attcttctat aaagaaacca attaaagatg ctaaaattga
     4021 tgcaactatt attactaaat tgcttttgaa taatgcatat aaaataacag aaataatgat
     4081 tgatgatata aatactacaa tataaatctt attttttatt tgagaaacta ttaaagctat
     4141 aaacatagaa gtcaatatga agccagaaat agaactgtct atagatatac tttctcctaa
     4201 aaatgctcca ataaaattag ctaaaactga tgaaattaag cagaagaaat taagataaat
     4261 agcatttcta tcagaccaat ttccagcagt aaatttttca taattaactg caaaagtttc
     4321 atctgttata gtatgacaaa atggcaatat aaattttgga cttttatttt ttatgtacat
     4381 gttcaaatta gaactcatta gaaaatgtct taagttaact ataaatgtag tcaaaacaat
     4441 agatgttaca cttgcaccag tagaaatcat tgaagctgca atgaattgag aacttcctcc
     4501 aaatactaaa gttaccatta gtgctatttg aaaaggtgaa agaccagatt tttgtaatag
     4561 tattcctcct actataccta taggtatata acctaagaat ataggaattg aagcaataaa
     4621 gctttctttt aattgttgag ttctttccac aataaatcac tccttttgta ttaaatgtat
     4681 taaagtatta gtaaaacaga aaaatagatt aattgtataa ttgcaattat aattaaaaat
     4741 aaatttggat taatatataa aatactatac aacaaataaa taatcttaaa cggttattaa
     4801 attttatcta tttgttatta tgatgtaata atacatatta atctctataa gttaattact
     4861 atctggtgta attttatttt aacaacaaaa aaaaatacac acaattaaaa tattgtgtgc
     4921 aatacaatta ttttttctct tctaatagtc tttttaatac gctcagacca gctttaagtt
     4981 cttctgtgct ttctgtagca catacagcta ttcttattgc agaaattggt ttttcttttc
     5041 caacagcaaa acgttcagaa gcatagacct gtacaccttc tttaagtgct tgtatctcaa
     5101 atttttctgc cattattcca tcaggtagaa tcaaccatct aaatatacat tcttcatttc
     5161 ccaaaagatt atatccagat aaatattgat taataatctt gtttcttctt cttgcagatt
     5221 tacggcgtgc attaattaat ttatcggctt cacctgatgt aatcatgcga taagcaattt
     5281 ctgttaaaaa ataagattga gatagattaa tgttgtataa tgcgcttgat aatgcctctc
     5341 gatactgttt aggtgtagag atatatgcta gccgtaaact aggtgcaata atttttgata
     5401 aactcgtaat ataaattgtt tgattgggca gataggaagc cactggattt aaatgtgttt
     5461 cattaagtaa actatgaata gcatcctcaa taacaattaa attgtattta gatgcaatat
     5521 ttgcaatcat ttttcgtcca ttttgtgaca ttatatgtgt agttggattt tgataatctg
     5581 gtattatgta tagaccttta atattttcat ttttacaagc atataatagt ccttcttcac
     5641 taatctcatt atcttcttgt ttaattggaa ttagttgaat cccaagcatt ttagctgctg
     5701 tctttattcc aggataagtt aatgggtcta cacctattct atctccatgt tgaaacaaac
     5761 cagctaaaat agcaacaatt gcattttgtc caccacttgc aggaagtaag ctatctgatg
     5821 tagtttcaag cccagcttta taaattaatt tggcaatagc ttctttttgc catttagcac
     5881 catctctttg tccatattgg aatatagttt taaaatctat ttccttaatt atatgtttaa
     5941 acaaagtatt catttcttct agtgtgaaat ctggattcat tgtgcccatt tcaataaatg
     6001 taattttatt attactggac atcaagaata gatttgaacg cgtatcataa gatacaaaag
     6061 ttccacttcc tgtaactcca cttattagac cttttttttc acaaatttta aaagctctag
     6121 agatagtact cacattaaca tctaagaaat ctgccaattc acgttggggt ggtaatttag
     6181 tacctggtaa taaaaatcca ttgttgatat cttgttctag ttgttctgca agcgccttat
     6241 ataatatttg cccttttgaa ggtctctttg gtttccagtt cataggataa ttttcaaaag
     6301 aattaattgg cataagtttt cacctcacat tattaatttg attttttctt tatctaaaac
     6361 aataaattct aaagatacaa ataaaaactg ataggaaata attctatcag tttttgtctt
     6421 ttaattgatt tcaaatcttc ctataatttt tataccttct ttatcataaa gagggattgt
     6481 ttttttaaat atattaaaat ttctttttct tgtatataaa acagcttctt ctggtgtctt
     6541 tggttgatta tcacaatcgt acaaatctct tttttttacg tagccgactt ttttacctct
     6601 acctattgtt tgtataagtt ctggttcaat ggaatttcca tttgagtcta ttatatgtgt
     6661 accataggtt tctccatttt tattataatt aatcttagca atagtatatt ctacatcttc
     6721 attttgttta aaattggagt tgatagaaaa tattgaccct attattataa aggttaataa
     6781 aaacttaaga cctaaattaa ttttcttttt atcttgatta aacatagaat ttaacctctt
     6841 ttttaaaata atattttttt tatttagaaa ctgagatacg aatgatgaat acttcaaagt
     6901 tttttgatac tttattgtat ttaatattat atatgcatac tctttaattt cactcgtggt
     6961 acatttgtca atcacaattt catcacaaga taattcacat aattcatgaa aatatttttt
     7021 taataagtat aaaattggat tgaaccaatg tatgatacat attatactaa ttagaagctt
     7081 aaataagtta tcttttcttt tataatgaat taattcatgt ttaaagataa atcttaactc
     7141 tttattattg tacttttttt ctggaattat tattttacag cgtgttaaac ctataatggc
     7201 aggggaataa atacctttaa ccttatatat ctgaagtttt ttatttatac ttagttcttt
     7261 tgcttgttca tctaagatac tagtaatatc tatttctaaa atttcttttt taaaattttc
     7321 tatgtaatta taaaatttaa aatttgttct taaatagtaa aaagagattg ctataattcc
     7381 taatatccag atgtacataa atatatctaa agtaatgccc tggtcatatg gtatataatt
     7441 atcgagatta tgtttata
//
LOCUS       DAMJYN010000136         7334 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.142, whole genome shotgun sequence.
ACCESSION   DAMJYN010000136 DAMJYN010000000
VERSION     DAMJYN010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7334)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7334)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7334
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.142"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            153..1046
                     /locus_tag="PC466_003431"
     CDS             153..1046
                     /locus_tag="PC466_003431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDF2770783.1"
                     /translation="MQLYNTPFNTNKHLIYFFTSTLVLNWIFSLTPALLGITNTILGE
                     IIFYLAYTSPAIVGLFFISTIYPQSAKQDFIYRYLSFKEIRIKWILLTILFFALTFIT
                     SLIIGNYFNVKTSDIDWIHIAVFRPSKIAYMLLASFILSILSQEAGWRGYAIDKLLVR
                     FGFIGSSIILGLVCGIWYLGSYFTPNQIPYNLAQYSLFDAFLFIPNIVLLNFIINFVY
                     INTSRSILSAGLVHMMYYFFNIQLLLHYPIKLCVIAQYVQIIFGLIFLVYMISSNKFK
                     QKVNSEIEQIKSDDFEFELDW"
     gene            1224..2048
                     /locus_tag="PC466_003432"
     CDS             1224..2048
                     /locus_tag="PC466_003432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF2770784.1"
                     /translation="MFKIGEVSKLTQISIRMLRYYDELGILKPAEIDKYTGHRLYSVE
                     QISILQRIVLLRDSKFSVAEIANIVHNWNDEFVIKELNRKKNEIQKEIKHEQQRINKI
                     DKFIEAINCDKDEIHYNVVFKKIPSYKIISLREVVPDYQSEGILWEKLSKFIKEEHIE
                     VSRQPNNNIAFYHDEEVKDNGVDIEVGMVVKKIGKNKSGFIYRETEEIDMMACTMVYG
                     PYENIAGAYESFCYWLDKNSDYQISGINRQIGHKGEHNEINPENYLTEIQIPLIKV"
     gene            2147..2755
                     /locus_tag="PC466_003433"
     CDS             2147..2755
                     /locus_tag="PC466_003433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2770785.1"
                     /translation="MEKLLRGKIMKADSTKEQLINATIQLLSSHRDVSSITAREIVAK
                     ANVNLAMINYYFKSKEELINISIKKFLKRHMDEYKATHDTKNLAPKQQLREILIAFFD
                     FIGEHSQFIKISVPYILIQEEIVYPFEILPLIKAHYENQNNKKTEAEYRTIAYQITSF
                     IQLLFLRSNAFFKYSGIDILNVEQRNGLIDFQLDLLLVDITK"
     gene            2859..3035
                     /locus_tag="PC466_003434"
     CDS             2859..3035
                     /locus_tag="PC466_003434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770786.1"
                     /translation="MFFTFIGVISAILLLCTIICGLWIKLNNRNNDSNSHFTFSILSI
                     AFSLLIVVAFLVRN"
     gene            4331..5083
                     /locus_tag="PC466_003435"
     CDS             4331..5083
                     /locus_tag="PC466_003435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2770787.1"
                     /translation="MLKVNQLCKSYKTGNKTYPVLKNISFEINKGEFVAIMGSSGSGK
                     TTLLNCISCFIPIDNGEIILGNNNIRNLKEKELSEVRNQQLGFVFQDFMLFDGLSVFE
                     NICVPQIIKGSQVLQMENRAINLCELFGIEHIRKKYPAEISGGEKQRTAVARALMNNP
                     DLILADEPTGNLDSKSCRTVIESFLKAKQELDATILMVTHDSFAASFCDRVIVLKDGI
                     IYKEVVKSNSRHKFLDELLEVLKEMGGAQDDN"
     gene            5073..7184
                     /locus_tag="PC466_003436"
     CDS             5073..7184
                     /locus_tag="PC466_003436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2770788.1"
                     /translation="MTINKLYSKLRAYNWKNYTTLFFCIILSVVLVTSYALIYFSPTI
                     QNILPTGGDSRKQATMIFSVAILGCAVFTTYASSLFLKFKSKEIGIFMALGTDKKKLK
                     KLLFSEILLISIVCCFLGLILSIPVSFGIWKIFQLVIIDTREMTYHFGTQGFIYGFIF
                     SVFVTLCIFILSVKFINRTNIIDILNDQRISEPIQDVKDWYGILGIIFIILGIFLGYI
                     VPSLTINKLNYRLPSVWSFTYLLSLIGIYMIMTYIVVHAKRGKHPEKYYKNIISTSMM
                     RFMGRQTVKNMCVISFLIAGALFAVFYVPNMVAGIYDTLKNNPIDYTFTYNQRDKQVS
                     KKDIEQLADKHNIKIQNYMEIPSIELIVDGVESIYHKDGTIERVYMKKSSYDMFFNSK
                     DFSKLIDKPITIKNGEYLAVVNKGNENQDYKYTKFISSPVTEKEIPFRYAGKIIFNGS
                     FFQNRSMNAYVLNDEDYKSFTKDLSIKNYNNSILFNVDKDTYAFANDLKKEIIKRTSK
                     EMGMFSGYDEYVKKRYESTGRKYFMDEEYPSGEGHLKLDPNNNQLYLNWKYYPNFKIL
                     QSQDMIKNMAVFLMLFIYVAIICFTAVGIIAYTRGVTIAINHKQVFMDLNRLGANNDY
                     IKFCIRNQLKKVFSYPLIAGSFLIYLFNFMIMLNNDGRIVNSEVNALLINLGFIGICG
                     VYMYLIYLLTYKKFKKIIGIL"
BASE COUNT         2728 a          962 c          970 g         2674 t
ORIGIN      
        1 tatttagtgt aaaaataatt aatcaaaata taaaaaatag gatattatta taggcaataa
       61 ctaacatcaa acgataactt aatacatata aaaataaata aacaattaat aaaaattaaa
      121 acttcattat aaaacggaag gatagtgaaa aaatgcaact atataacacc ccctttaata
      181 caaacaaaca cttaatctat ttctttacat ctacgctagt attgaactgg atattcagtc
      241 ttacacctgc gttgctcgga attacaaata caatacttgg agaaatcatt ttttatcttg
      301 catatacatc accagctatt gtaggtctat tttttatttc tacaatctat ccacaaagtg
      361 caaaacaaga ttttatttat agatacctaa gctttaaaga aattagaata aaatggatac
      421 tattaacaat attatttttt gctttaactt ttattacttc gttaataatc ggaaattact
      481 ttaatgtaaa aacttctgat atagattgga tacacatagc agtgtttaga ccttctaaaa
      541 tagcttatat gctattagca agttttatat tgagtatact tagtcaagaa gctggatgga
      601 gaggatacgc cattgacaaa ttattagtta gatttggatt tataggctct tcaattattt
      661 tagggcttgt ttgtggaatc tggtatctag ggtcgtattt tacacctaat caaataccat
      721 ataatttggc acaatactcc ctatttgatg cttttttatt tataccaaac attgtacttt
      781 taaactttat aattaatttt gtatatatca atacaagtag aagcatttta tcagctgggt
      841 tagttcatat gatgtactat tttttcaaca ttcaattact tctacactac cctattaaat
      901 tatgtgtaat agctcaatat gtacaaataa tatttggttt aatatttctt gtatatatga
      961 tttcttctaa taaatttaaa cagaaggtaa attctgaaat tgaacagata aagtcggatg
     1021 attttgaatt tgagttagac tggtaatttt aatatgaatt ataaattaag ataatctatg
     1081 atttgatacg attactactt aaatataatt tactctctat aatttattgc aacatctgga
     1141 aaataattgt atttccacaa tcgcttgaag tatataaaaa caaaatatat actaattata
     1201 agtgaaaagg aggtcatatt ttcatgttta aaataggaga ggtttcaaaa ctaacacaaa
     1261 tttctattcg tatgttgcgt tattatgatg aacttggtat tttaaagcct gcagaaatag
     1321 acaaatatac aggtcataga ttatactcag ttgaacagat ttcaatatta caaagaattg
     1381 tattattgag agattcaaaa tttagcgttg cagaaatagc aaatatcgta cataattgga
     1441 atgatgaatt tgtaattaaa gaattgaata gaaaaaagaa tgaaatacaa aaggaaataa
     1501 agcacgaaca acaaagaata aataaaattg ataaatttat agaagctata aactgtgata
     1561 aagatgaaat tcattacaat gttgtcttta aaaagattcc aagttataaa atcatatcac
     1621 ttagagaggt agtcccagac taccaatctg aaggtatact ctgggaaaag ttatctaaat
     1681 ttattaaaga agaacatata gaagtatcac gtcaacccaa caataatata gctttttacc
     1741 atgatgaaga agtcaaagat aatggtgtag atattgaagt tggaatggtt gtaaagaaga
     1801 ttggaaagaa caaatctgga tttatatatc gtgagacaga agaaattgat atgatggcat
     1861 gtactatggt ttatggtcca tatgaaaata tagctggtgc atatgaatcg ttctgttatt
     1921 ggttagataa aaatagtgat tatcaaatat caggtataaa tagacaaatc ggtcataagg
     1981 gtgagcataa tgaaataaat cctgaaaatt atcttacaga aattcaaatc ccccttataa
     2041 aagtctaatc gattagtact taaatactta agtactaatc acccattgac atcccaaaat
     2101 tttcatgata gtatctaaac gtgtattaaa catgtttaat ttttttatgg agaaactttt
     2161 aaggggaaaa attatgaaag cagattcaac aaaggaacaa ttaattaatg ccacaatcca
     2221 gttactatct tcacatagag atgtttcaag cattacggct agagaaattg tagctaaagc
     2281 aaatgtcaat ttagctatga ttaattatta ttttaaatct aaagaggagt taattaatat
     2341 ttctattaaa aaatttttaa agcgtcatat ggatgaatat aaggctacac atgatactaa
     2401 aaatttagca cctaaacagc aattaaggga aatactaatt gcattttttg attttatagg
     2461 tgaacatagc caatttataa agatttctgt accctatata ttgatacaag aagaaattgt
     2521 ttatccattt gagatactac ctttaattaa ggctcactat gaaaatcaga ataacaaaaa
     2581 aactgaagct gaatacagaa ctattgcgta tcaaataact tcatttattc agttgctttt
     2641 tcttcgttct aatgcttttt tcaagtatag tggtattgat attcttaatg ttgaacagag
     2701 aaatggttta atagattttc aattagattt attattggta gatattacaa aataatacta
     2761 tattaatttt ttatgtacat ttttttattt tatggtaacg tttgaaaata ttctcattga
     2821 ctaaaaatac ttgcattaaa taagggggag gaattttaat gttttttaca tttataggag
     2881 taatatcagc aattttattg ttgtgtacaa ttatatgtgg tttatggata aaacttaata
     2941 atcgtaataa tgactctaat tctcacttta ctttttcaat actttcaatt gctttttcac
     3001 tgttaattgt ggtggccttt ttagtaagaa attaatgtct ttgttatgct ggggtttatt
     3061 attatagatt tttattattg catgattttt actatattat agtattttta ttatattaca
     3121 gggtcttatt tattatagtg ttttgttatt acagcatttt attatattac agagtcctat
     3181 ttattatagg atttttatta tattgtaaaa tcttatttat tataggattt tgttatatta
     3241 cagactttta ttatattaca atctcttatt tattgcagtg ttttgttatt acagtatttc
     3301 tattatattg caaactctta tttattatgg tgttttgtta ttgcaacatt tctattatat
     3361 tataaagtct tatttattac agttctttgt tatactacag acttttatta ttacagcatt
     3421 tctattacaa tctcttattt attacagttc tttgctatac tacagacctt tattattgca
     3481 acatttctat tacattgcaa agtcttattt attacagttc tttattatac tacagacttt
     3541 tattattaca acatttctat tatattacaa tctcttattt attacagttc tttattatac
     3601 tacagacttt tattattaca gcatttctat tacattgcaa agtcttattt attacagttc
     3661 tttattatac tacaaacctt tattattaca acattttatt attttaacgt ctttactata
     3721 atatagtaat attttaatat ctcaaaatca tatcaatcac ttttcagcat agtctaaaat
     3781 acttccactt tctaaaatta tctatcatac ctatactaat aatacttttt aaccttttta
     3841 ttatacattt caattgtttt taacgaccta tttatttcca aaactccaat atattttctc
     3901 aattacattg tgttaataac ccctaaatcc tttcaaatta tttacaatac attccattaa
     3961 ataatcttac tgctctataa ttcttttttt ctttttaacc ctactataca ttatttacat
     4021 catttttttc aatacaacat tcgttattct ataacctttt tacttttact atataccttt
     4081 tttctaacta caccttcaat gttccacatc atattacttt agcacaacaa ttaataccta
     4141 aaaataaccc tctaaatcct ccaataatat aatcaattta actataataa taacctctca
     4201 cactatccaa acaatatatt ttcaaacatt acaaaaaaac atccaactat tacaatattg
     4261 ctcatatccc tcctcccctt tcaaatgcta tcattgactt acaagataaa tgaaagtgag
     4321 gatgatatat atgcttaaag taaaccaatt atgtaaatca tataaaacag gcaataaaac
     4381 atatcctgta ttaaaaaata tttcttttga aatcaacaaa ggagagtttg tcgcaatcat
     4441 gggttcatca ggaagtggaa aaactactct tttaaattgt atttcatgtt ttatcccaat
     4501 tgataatggg gaaataattc ttggaaataa taatataaga aatttaaaag aaaaggaact
     4561 ttcagaagtt agaaaccaac aactaggatt tgtattccaa gatttcatgc tatttgatgg
     4621 tcttagtgtc tttgaaaata tatgtgttcc acaaattatc aaaggtagtc aagtcttaca
     4681 aatggaaaac cgtgcaatta atctatgcga gctatttggt attgaacata tcagaaaaaa
     4741 ataccctgcc gaaatatctg gtggagaaaa acagcgtaca gcagtagcaa gagcactcat
     4801 gaacaaccca gatttaatat tagcagatga accaactggt aaccttgata gtaagtcttg
     4861 tcgtacagtc attgaatcat ttttaaaagc aaagcaagaa ttagatgcta ctatactcat
     4921 ggttacacac gatagctttg cagcaagctt ctgcgaccga gttattgtgc ttaaagatgg
     4981 aataatttat aaagaagttg taaaatcaaa ttcaagacat aaattcctag atgaattact
     5041 agaagtttta aaagaaatgg gaggcgctca agatgacaat taataaatta tacagcaaac
     5101 ttcgagccta taattggaag aactatacaa ctttattctt ttgtataata ctttctgtgg
     5161 tattagtaac ttcatatgct ctaatttatt ttagcccaac aatacaaaac atacttccaa
     5221 ctggtggaga tagcagaaaa caggctacaa tgatattctc agttgctata ttaggatgcg
     5281 ctgtctttac tacatacgct tcttccctct ttttaaaatt taaaagcaag gaaattggta
     5341 ttttcatggc tctaggaaca gataagaaga aattaaaaaa acttctattt tcagagatat
     5401 tgttaatttc aatagtatgc tgttttttag gtcttatatt aagtattcct gtatcttttg
     5461 gtatatggaa aatatttcaa ttagtgatta ttgataccag agaaatgaca tatcattttg
     5521 gaactcaagg attcatatat ggatttatat ttagtgtatt tgtgacatta tgcatattta
     5581 tactttctgt aaaatttatt aatcgtacaa atataattga tatattaaat gaccagagaa
     5641 tatctgaacc aatacaggat gtaaaggact ggtatggtat attaggtata atttttatta
     5701 tactaggtat ttttctagga tatatcgtac cttcactaac tataaacaaa ttaaattata
     5761 gactaccatc tgtatggagc tttacttatc tactctctct tattggaata tatatgatta
     5821 tgacatacat agttgtacat gctaaaagag gaaaacatcc agaaaaatac tataaaaaca
     5881 tcatatcaac tagcatgatg agatttatgg gaagacaaac agtaaaaaac atgtgtgtta
     5941 tttcattttt gattgcagga gcattatttg ctgtattcta tgttcctaat atggttgcag
     6001 gtatctatga tactcttaaa aataacccta tagattatac ttttacctac aatcaaagag
     6061 ataaacaggt atcaaaaaaa gatattgaac aattagcaga taaacacaat ataaaaattc
     6121 aaaactatat ggaaattcct tctatagaat taattgttga tggtgtagaa tcaatatatc
     6181 ataaagatgg aactatcgaa agggtatata tgaaaaaaag ctcctatgat atgttcttta
     6241 attctaaaga tttttccaag ctaattgaca aaccaataac tataaaaaat ggtgaatatc
     6301 ttgctgttgt aaataaagga aatgaaaatc aagattataa atataccaaa tttatatcaa
     6361 gcccagtcac agaaaaagaa atccccttta gatatgctgg aaaaataata tttaatggtt
     6421 ctttttttca aaatagaagt atgaacgcct atgtccttaa tgatgaggat tataaatcat
     6481 ttactaaaga tttatccata aaaaattaca ataattctat actatttaat gtagataaag
     6541 atacctatgc ttttgccaat gacttaaaga aagaaattat aaaaagaaca tctaaggaaa
     6601 tgggcatgtt cagtggttat gatgaatacg taaaaaaacg ttatgaatca actggaagaa
     6661 aatattttat ggatgaagaa tatccaagtg gtgaaggtca tttaaaacta gacccaaaca
     6721 acaatcagtt gtatcttaat tggaaatact atcctaactt taaaatttta caaagccaag
     6781 atatgataaa aaacatggca gtcttcttaa tgttattcat atatgtggca atcatatgtt
     6841 ttacagcagt aggaatcatt gcatatacaa ggggtgttac tatagctata aatcacaagc
     6901 aggtctttat ggatttaaat cgattaggag caaacaatga ttatataaag ttctgtatta
     6961 gaaatcaatt aaagaaagta ttttcatacc ctcttattgc aggaagtttt ttaatttatc
     7021 tgtttaattt tatgattatg ttaaataatg atggtagaat cgtcaatagt gaggtcaatg
     7081 ctcttttgat aaacttaggt tttataggga tttgtggagt ttatatgtac cttatatatc
     7141 tattaactta taagaaattc aaaaaaatta ttggtatttt ataataagga aggttgttag
     7201 atttttaaag taataaaatc attacttttt ataataagaa aagcattagc attttaaatt
     7261 aaaaaaggtt attagatttt tatgatatga aaagtcattg tatttttata gtaagataat
     7321 tatttgcttt ttat
//
LOCUS       DAMJYN010000137         7133 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.143, whole genome shotgun sequence.
ACCESSION   DAMJYN010000137 DAMJYN010000000
VERSION     DAMJYN010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7133)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7133)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7133
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.143"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            153..3332
                     /locus_tag="PC466_003437"
     CDS             153..3332
                     /locus_tag="PC466_003437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HDF2770789.1"
                     /translation="MKIDMIYKLIRRNTEPSRWSRGVKYYTNQLVDYIDIDIDDLQNN
                     LLTFRGGVNSEDNYSFYFNSITIDIKHFKIIENDCSCADCQSKGKSIFICKHIVAIVI
                     KSLKQIKNKRDVPPILIDILGADKDKLSNTNSKTSLDLSKQLLSLLDNTKRERVNLDV
                     LINVDSNKAIAEFKIGIDKMYILKNITEFAYSKLNGYELDFGKKFTYNPNIHYFADED
                     EKLVDIIEEYGTNLSYNFSSSHSKKFMEINASSLKQFLNAIKYKDFTLIFSKEEYHPK
                     ILNDTLPVRFDFKNIEDKIVLYSKDSLPVPLTKKNDVLLYDGNIYLLSHKKAHDYSKI
                     YQILSKTKELKFDKEDSKDVLGLLVPRLKSISQEVHLDDNIKNNITKDFKSEFYFDMI
                     DGNICCDVKYIYDDEDKKFVLPNIQKETTIENKLTSSQFTKENNHYVFKGTDYDLFTF
                     LDLQLESLKEFGDIYYSEKFKLKKIYNASSIQASINQTNQNYLEFNFNISDINPKEYK
                     DILKAFQEKRTFYKLKDGNFIDLSERETKDFFELVENLDIMDKSKNNKIYKNKALYIN
                     DVIRSKNLKFIDGKKELDSICEKFRNFDSINLEIPANLNANLRDYQINGLNWFKVLDY
                     YKFGGILADEMGLGKTIQTIAFLLSLSNKKSLIVTPTSLIYNWKNEFEKFAPDIKVLL
                     IHGNKRDREKCFMELENFDVILTTYGTLRNDLEKYSEIKFDYCILDEAQNIKNPVALV
                     TESVKSINAENKFALTGTPMENNLLELWSIFDFIMPGYLYSKAKFQELFINKEDNVKN
                     LKKLIKPFILRRSKKQVMKELPDKIEKNFFVELNKEQKKIYSVYSKDIQDKMKDKNLK
                     KDKIVIFSYLTKLRQLCLDPSIVVKDYNKKSSKIETCLEILRDSINENHKILLFSQFT
                     SVLKNISKELDKYKIKYHYIDGKTNAKERLELVDEFNNSMDKKVFLISLKAGGTGLNL
                     TSADMVIHFDPWWNPSVENQASDRAHRFGQKNSVQVIKLIAKGTIEEKIIKLQESKKE
                     LINQFINGELSNEGVLKSLSDEEIIDLFN"
     gene            complement(3513..3596)
                     /locus_tag="PC466_003438"
                     /pseudo
     CDS             complement(3513..3596)
                     /locus_tag="PC466_003438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009005413.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
     gene            complement(3617..4381)
                     /locus_tag="PC466_003439"
     CDS             complement(3617..4381)
                     /locus_tag="PC466_003439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF2770790.1"
                     /translation="MAYFNYNDKQCYYNEIGDGTPLLFLHGNTASSKMFNDIIDFYKD
                     EYKVILIDFVGHGKSQMVDKFSADLWFDEAMQVICFLEAMNYKKVNIIGSSGGALVAL
                     NVALERPDLVNKVIADSFEGEVPLESFVQNVKIEREASKQDDGAKAFYIYNQGENWEK
                     VVDNDTEAIFEHYKTIGKFFHKPLETMQPEVLLTGSREDEFVSLISSDFFENTFSLLL
                     EKIKNGKMYLFDKGGHPAILSNGLDFSNVAKKFLEE"
     gene            complement(4618..6111)
                     /locus_tag="PC466_003440"
     CDS             complement(4618..6111)
                     /locus_tag="PC466_003440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HDF2770791.1"
                     /translation="MKYTFEKFKLNEKILKSLKSLGYNIPSRVQREVIPKLLKGQNLV
                     VRSKTGSGKTVSFAIPLCENINVDCNNIQALIVVPTRELALQVKDEISDIGRLKKVRC
                     SAIFGKQSIKDQIAELKQRVHIVVATPGRILDHINKGSIKLENVKYLVIDEADKMFNK
                     GFVEQMEKILLNLPKEKIVSLFSATIDEEIKYICEKYMLDYSVINIEENESDTNQKTR
                     QIDDKIIKANGREKYILLKELIYSENPKSVIIFCNTKEKVSKLYNKMSKEGFLIRELH
                     ADLSQERRIFVIKDFKNQKFNILVSSDVASRGIHIDDISLVINYDVPQDKENYIHRIG
                     RTGRKGNSGKAITIVTEKDEKYIENIETYIGYKVNELKDIEKSRITHGKILFEEYSKG
                     ILKKVSKRKKVDKNSYKSKDIKLNIESEVVKLYLNAGKKKKIRVLDIVGAFSNIKGIT
                     NDDIGVIEVQDLCSYVDILNYKGDLILKKYKEIPIKKKMVKVKRDIR"
     gene            complement(6436..6978)
                     /locus_tag="PC466_003441"
     CDS             complement(6436..6978)
                     /locus_tag="PC466_003441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDF2770792.1"
                     /translation="MKICITVGHSILKGGKSTGVNGIVDEYNYNKKLAPMLAEMLISQ
                     GNTVDVIICPERHFMSEREEFFYRVPKVNSGKYDLLVELHLNKADGTQCGTEVLYYGT
                     EGLEYAKRVSNRLGELFENRGAKKRENLYILRNTNPVAIQIESFFCDNVNDCNKANES
                     GYDYIARLITEGILNKDINM"
BASE COUNT         2633 a         1001 c          795 g         2704 t
ORIGIN      
        1 aattcaataa aaatctaata gtaaattgtt atttacacat atattgtaat agataaaagc
       61 tattcatatc tgccttaatt ttagtcttaa atttagagtg taaattgaat gcatttagat
      121 tataatatat acagtgaggt aaggtgaata atatgaaaat agatatgata tataaactaa
      181 taagaagaaa tacagaacca tcaagatggt caagaggtgt aaaatattat actaatcaat
      241 tagttgatta tatagacata gatattgatg acctacaaaa taacctgttg acatttcgtg
      301 gtggagtcaa ttctgaagat aattatagct tttattttaa ttcaataact atagatataa
      361 agcactttaa gataattgaa aatgattgta gttgcgctga ctgtcaatca aagggcaaaa
      421 gtatttttat atgtaagcat atagttgcta ttgtgataaa aagcttaaaa caaataaaaa
      481 ataaaagaga tgttcctcct attctaatag atatattagg tgcagataag gataagcttt
      541 ctaatacaaa ttctaaaaca agcttagatt taagcaagca attactttct ttgttagaca
      601 atactaaaag agaaagggtt aatttagatg tattgataaa tgtggattca aataaagcaa
      661 ttgctgaatt taaaatagga attgataaaa tgtacatttt aaaaaacatt actgaatttg
      721 catattcaaa acttaatgga tatgaattag attttgggaa gaaatttact tacaacccca
      781 acattcatta ttttgctgat gaagatgaga agttagtaga tattatagaa gaatatggga
      841 caaatctttc atacaacttt tcttcatcac attcaaaaaa atttatggag ataaatgcaa
      901 gctctttaaa acaattttta aatgctatta agtacaagga ttttaccctt attttttcta
      961 aagaggaata tcatccaaag atattaaatg atactctacc tgtaaggttt gattttaaaa
     1021 atatagaaga taaaatagtc ttatattcta aagattcact acctgttcca cttactaaaa
     1081 aaaatgatgt acttttatat gatggcaata tctatttatt atcacataaa aaagctcatg
     1141 attattcaaa aatatatcaa atattatcaa agactaaaga gttaaaattt gataaagagg
     1201 attctaagga tgttttagga ttgctagttc ctagattaaa atctatatct caagaagttc
     1261 atttagatga taacataaaa aataatataa caaaagattt taaatctgag ttctactttg
     1321 atatgattga tggcaacata tgttgtgatg taaagtatat atatgatgat gaggataaaa
     1381 aatttgtgct ccccaacata caaaaggaaa ctactattga aaataaactt acttcttcac
     1441 aatttacaaa ggaaaataat cattatgtgt ttaaaggaac tgactatgac ctatttacat
     1501 ttttagattt acaattagaa tctctaaagg aatttggaga tatatattat tctgagaagt
     1561 ttaaattgaa aaaaatatat aacgcttcat caattcaagc ttcaatcaat cagactaacc
     1621 agaattacct agaatttaat tttaatatat ctgatataaa tccaaaagag tacaaggata
     1681 ttttgaaagc ttttcaagaa aaacgtactt tttataaact taaagatgga aactttatag
     1741 atttatcaga aagagaaaca aaagattttt ttgaattagt tgaaaatcta gatataatgg
     1801 ataaatcaaa aaataataaa atttataaaa ataaagctct atatataaat gatgtaatac
     1861 gtagtaaaaa tttaaagttt atagatggta aaaaagaact agacagtata tgtgaaaaat
     1921 ttagaaattt tgatagcata aatttagaaa ttcccgcaaa tttaaatgca aaccttcgtg
     1981 attatcaaat aaatggcctc aattggttta aagttttaga ttattataaa tttggtggta
     2041 tattagctga tgaaatgggt cttggtaaaa caatacagac tattgcattt ttattatcat
     2101 tatctaataa aaaaagtctt attgttacac cgacatcact catttataat tggaaaaatg
     2161 aatttgaaaa gtttgctcca gatataaaag ttttattgat acatgggaat aaaagagata
     2221 gagaaaaatg ttttatggaa ttagaaaatt ttgatgtaat acttacaaca tatggtactc
     2281 ttagaaatga tttagaaaaa tatagtgaaa taaagtttga ttattgtata ttagatgaag
     2341 ctcaaaatat aaaaaatcca gtagctttag taactgagtc tgtaaaaagt ataaatgcag
     2401 aaaataaatt tgcactcact ggtacaccta tggaaaataa tctactagaa ttatggtcta
     2461 tatttgattt tataatgcct ggctatctat atagtaaagc aaagtttcag gaattgttta
     2521 taaataaaga ggataatgtt aaaaacctga aaaaattaat aaaacctttt attcttagaa
     2581 gaagtaaaaa acaagttatg aaagaacttc cagataagat tgaaaaaaac ttttttgttg
     2641 aattgaataa agagcagaaa aagatatata gtgtatattc aaaagatata caagataaaa
     2701 tgaaagataa aaatctaaag aaagataaaa tagttatatt ttcttattta actaaactaa
     2761 gacaactttg tttagaccca agtatagtag taaaagatta caataaaaaa agttcaaaaa
     2821 ttgaaacatg tttagaaata cttagggata gtataaacga aaaccacaaa atattattgt
     2881 tttcacaatt tacttctgtg cttaagaaca taagtaagga acttgataag tataaaatta
     2941 aataccatta tatagatggt aaaactaatg ccaaagaaag acttgaactt gtagatgagt
     3001 tcaataatag tatggataaa aaagtttttt taatatcttt aaaagcaggc ggaactggtt
     3061 taaatcttac atctgctgac atggtaattc actttgaccc atggtggaat ccatcagtag
     3121 aaaatcaagc tagtgataga gctcatagat ttggtcaaaa aaattcagta caagttataa
     3181 aattgattgc taaagggact atagaagaaa aaataataaa attacaagaa agtaaaaaag
     3241 agcttataaa tcaatttata aatggagaac tttctaatga aggtgtatta aaaagtctat
     3301 ctgatgaaga gataatagac ttatttaact aaattattta atcctacagc ttaactatat
     3361 aaatttattc taacatttat atagttaagc tacaatatct gaataaataa aatttcatat
     3421 tgttatttaa tcccaacttt acaatctaat gatatctctt tctatacata ttgcatatac
     3481 aaatgtaata acttgactat tagaatattt tgttttaaca atcctatttc atcataataa
     3541 tgaagtatat gtacactcac ttttgtaagt tttgcaatcc attttacagt tttcattatt
     3601 gtaaattttg gttaaattat tcctctaaaa atttctttgc tacatttgaa aaatctaatc
     3661 cattcgataa aattgcagga tgaccacctt tatcaaacaa atacatttta ccatttttaa
     3721 tcttttcaag aagtaatgaa aaagtatttt caaaaaaatc actagatatt agagatacaa
     3781 actcatcttc tctacttcct gttaaaagca cctctggttg catagtttct agaggcttat
     3841 gaaaaaattt tcctatagtt ttataatgtt caaaaatagc ttctgtatca ttatctacaa
     3901 ctttttccca gttttctcct tgattataaa tataaaaagc ttttgcacca tcatcttgct
     3961 ttgatgcctc acgctctatt ttaacatttt gtacaaatga ctctaaagga acttctcctt
     4021 caaaactatc tgcaattacc ttattcacta aatcaggtct ctcaagtgca acatttaatg
     4081 caacaagagc tcctccacta ctaccaatta tgtttacttt tttatagttc attgcttcta
     4141 aaaaacatat cacttgcata gcctcatcaa accataagtc agcagaaaat ttatcgacca
     4201 tttgagattt tccatgacct acaaaatcaa ttaatattac tttatattca tctttataaa
     4261 aatcgattat atcattaaac attttggaag aggctgtatt tccatgtaaa aaaagtaatg
     4321 gtgtaccatc cccaatttca ttatagtagc actgtttgtc gttatagtta aaatatgcca
     4381 tatattacct cctttaatat ccctataggt atatatttat tacttatatt taaaatgact
     4441 attgtcataa acatttaaaa atagtatagc ttagaatgta gataaagtca acattccttt
     4501 ccttaacaac ttctattgtt ttttgaaact tcatttcgat aacagaataa ttcataaata
     4561 ttgatactct tacttaaata tatgatttca tcatcagaga gagcagtaat aactaaatta
     4621 tcgtatatct cttttcactt taaccatttt tttctttata ggtatctcct tatatttttt
     4681 taatatcaaa tctcccttat aatttaatat atctacatat gaacataaat cttgaacttc
     4741 aattacacct atatcatcat tagttatacc ttttatatta ctaaatgcac caactatatc
     4801 taaaactctt attttcttct tcttaccagc atttaaatat aatttaacaa cttcactttc
     4861 tatatttagt tttatatctt tacttttgta agaattttta tcaacttttt ttctctttga
     4921 tacttttttt aggattcctt ttgaatattc ttcaaacaaa attttgccat gtgtaattct
     4981 acttttttct atatctttta attcatttac tttatatcct atatacgttt ctatattctc
     5041 tatatatttt tcatcctttt cagttactat agtaattgcc tttccactat ttccttttct
     5101 cccagttcta cctattctat gtatatagtt ttctttatct tgtggcacat cataatttat
     5161 tactaaagaa atatcatcaa tatgtattcc tctggacgct acatcactac taactaatat
     5221 attaaatttt tggtttttaa aatccttaat tacaaaaatt cttctttctt gtgataaatc
     5281 tgcatgtaac tctcttatta aaaaaccctc tttactcatc ttattatata atttagatac
     5341 tttctctttg gtattacaaa atattatcac actctttgga ttttcgctgt atattaattc
     5401 ttttaaaagg atgtacttct ctcttccatt tgccttgatt attttgtcat ctatttgtct
     5461 tgttttttga ttagtatcgc tctcattttc ttctatattt ataacactgt aatctagcat
     5521 atatttttca catatatatt ttatctcttc atctattgta gctgaaaaaa gacttactat
     5581 tttctcctta ggtaaattta ataatatttt ttccatttgt tcaacaaaac ctttattaaa
     5641 cattttatct gcctcatcta ttactaaata ctttacattt tccaacttaa tagaaccttt
     5701 atttatatgg tcaagtattc tgcctggagt agctacaaca atatgaaccc tttgtttcaa
     5761 ttcagctatt tggtctttta tagattgttt gccaaatata gcactacatc tcaccttctt
     5821 tagtctccct atatctgata tctcatcttt tacttgcaag gctaattctc ttgttggaac
     5881 cactataaga gcttgaatat tattgcaatc tacatttata ttctcgcata aaggtattgc
     5941 aaaacttact gtctttccac ttcctgtttt tgacctaact actaagtttt gaccttttaa
     6001 taattttgga ataacttctc tttgtactct agaaggtata ttatatccta aactcttcaa
     6061 tgacttaagt atcttttcat ttaacttaaa tttttcaaat gtatatttca tatattacca
     6121 ccttattata tttatcttat ctatatattt ttctacatta tattattata atacaaggtt
     6181 ctactatttt tatattattt attagactga agataaaaat atatactcta taaacctata
     6241 gtttagtagc aaatcaatta aatttttata tttaaatacc tccttaaata tactgataaa
     6301 tcaatattta ggaggtatct cttgtcaata atcaaactaa tctatatttt gaaagtttaa
     6361 attatactaa tacattgtat ttttatttat atctaatatt aaaaggtatt aatcaatacc
     6421 taaatcacca taatctcaca tatttatatc tttattcaat ataccttctg taatcaatcg
     6481 tgctatataa tcataacctg attcatttgc tttgttacaa tcattcacat tatcacagaa
     6541 aaaactttca atctgtattg caactggatt tgtatttctc aatatatata aattttctct
     6601 ttttttagct cctctatttt caaataattc tccaagtcta ttagatactc ttttagcata
     6661 ttctaatcct tcagtgccat agtaaagcac ttctgtacca cattgtgttc catcagcttt
     6721 atttaaatgt agctctacta ataaatcgta tttaccactg tttacttttg gaactctata
     6781 gaaaaattct tctctttctg acataaagtg cctttctgga caaattatta catctactgt
     6841 attaccttga cttataagca tctcagctaa cataggagct aattttttat tataattgta
     6901 ttcatcaact ataccattta cacctgtact tttaccacct tttagtatac tatgacctac
     6961 tgttatgcat attttcattt acttttttca ccttctttta agccaatttt tatataatag
     7021 taatataatt ttaaagttat tactaataat aatatattaa ttgaagaagg taaaagttct
     7081 ccgtgattat cattttttta acatatttgt cttattttat cataagtcta tat
//
LOCUS       DAMJYN010000138         6752 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.144, whole genome shotgun sequence.
ACCESSION   DAMJYN010000138 DAMJYN010000000
VERSION     DAMJYN010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6752)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6752)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6752
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.144"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(32..1717)
                     /locus_tag="PC466_003442"
     CDS             complement(32..1717)
                     /locus_tag="PC466_003442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2770793.1"
                     /translation="MKYLIEIAKKERLLVFIYLALGIGIELLNSFSANYYQSLIDRFN
                     NSTINFHIIFIYGTVLVTLCLLRYIDEYPGRRLEHSFFLDLKLKALEKMSKIDYLEYQ
                     MLGTGKLIQKIENGANAGRNIFFNFLLAVVRKIIPSILFSMVFIYRIDKKVMFTILIG
                     YFIVFIITNLLIKALYQIKEHILINEEKMNHFLVRGFVEMVVFRVNKRFEYEICQSKF
                     AKKEIIDSRVKMTLIHEAFFTIFSLIVTFIKMLIIVYSWKTKTISIGSIIALITLLDN
                     AYTPIAIFNVLYIQFKLDKAAYKRYTDILELNNDGQLLAGKEVNLMYGNIEFNEISFL
                     YNNKREIFNKLSLSIKSGEKVAIVGESGSGKSTLIKLLIGLLKPSEGTIFIDDYNLLE
                     MNLNSYYNYVTYVSQDSPIFDGTLRENIVFGKTIKSNDIIEVLEKVGLKNLYLKLEAG
                     LDTKLGEKGTTLSGGEKQRLALARLWFSDAKIIILDEATSALDNITEEKVMLNVMEFL
                     KDKTTIMIAHRFNSIKNVENIIVLKEGSIIGSGSFKKLLDGNLYFRELYYTMS"
     gene            complement(2640..3221)
                     /locus_tag="PC466_003443"
     CDS             complement(2640..3221)
                     /locus_tag="PC466_003443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDF2770794.1"
                     /translation="MNNKKHWYDYLWIFSSIYLVLGFVNIIFAWIGLICFFVPLAISI
                     VKGNKAYCNKYCGRGQLFNLLGNKLKLSRNRDIPKFIRSKWFRYGFLTFFMVMFANML
                     FSTYLVFEGSRNFKEVVTLLWTIKMPWQWAYHGTLVSPWVVQFAFGFYSVMLTSTVLG
                     LITMILFKPRSWCVYCPMGTMTQMICKAKSKSV"
     gene            complement(3214..3444)
                     /locus_tag="PC466_003444"
     CDS             complement(3214..3444)
                     /locus_tag="PC466_003444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDF2770795.1"
                     /translation="MSNKKKKYANILANECVACGSCIKACPRSAISVPCGISAKINRD
                     LCVGCGICEKICPASVIEIITILKEEEGKCHE"
     gene            complement(4769..5044)
                     /locus_tag="PC466_003445"
     CDS             complement(4769..5044)
                     /locus_tag="PC466_003445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDF2770796.1"
                     /translation="MLELTKIIELLEEHKIEVSIPKELHKYSLLEYLELCQQSGGTYF
                     YIKTLEGALKEARNELMIKLFNGKNYMELARMFEMSVINVRHIVRKK"
     gene            complement(5120..6421)
                     /locus_tag="PC466_003446"
     CDS             complement(5120..6421)
                     /locus_tag="PC466_003446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF2770797.1"
                     /translation="MGKSKDVEIEKSILGTILLDNKLSYKLDELNENMFMNDICLEIF
                     KIMKELKKENIVIDVATVKSKIDRKSLAIKTSDVTNLITWGQNFGLDGHIKILKENLA
                     RRSINQNCQNLLHSLNLGENIDTCIYKFESNIKEILDKDTYENDDVNSIAGKVLDFLE
                     NKKDIGFKFGIKLLDTTIGGLFKGELTTIAAKSGVGKTALALQIMLNSFKQGKKTLFI
                     SREMTSEQVFMRNICRVTGVSTRNMKSKEIDENDWKLIVNAIGDLSENNLIYINDKID
                     TISAIRKRIRQVKPDLLIVDYVQLLTSQKSMDKREREVATFSRELKNMTLDFNIPVIQ
                     LSQLNDEMKDSRPYGDRPMRDSKAIYHDSNNVVYIHQLKGSDYEEAVRDIGESEEAVR
                     ASEYRGIKMVDLIVAKCRDGQTRHKHFCYFGDKLHFQELNY"
BASE COUNT         2319 a         1235 c          550 g         2648 t
ORIGIN      
        1 agaaaaatat tttcttatac ttacataata attatgacat tgtatagtat aattctctaa
       61 aatataaatt accatctaat agttttttaa agctaccact acctattata ctcccctctt
      121 taagaacaat tatattttca acattcttaa ttgagttaaa tctgtgagca atcataatag
      181 ttgttttatc tttcaaaaat tccataacat ttagcataac tttttcctct gtaatattgt
      241 ctaaagctga tgtagcttca tctaatataa ttatcttagc atctgaaaac caaagccttg
      301 ctaatgctag cctctgcttt tctccacctg ataatgtagt tcctttttca cctaatttag
      361 tatctaaacc agcttctaat tttaagtata aattttttaa acctactttt tctaagactt
      421 caataatatc attacttttt atagtttttc caaatacaat attctcacgt aaagttccat
      481 caaatatagg tgaatcctgt gacacatatg taacataatt atagtaacta tttagattca
      541 tctcaagtag attataatca tctataaata tagttccttc gctgggcttt aataatccaa
      601 ttaatagttt aattaaagtt gatttaccag aaccactctc tccaacaata gctacttttt
      661 ctccactttt aatacttaaa ctaagtttat taaatatctc tcgcttatta ttatacaaga
      721 agctaatctc attaaattca atatttccat acattaaatt aacttcttta cctgctaaca
      781 gttgaccatc attattaagt tccaaaatat ctgtatagcg tttatatgct gctttatcta
      841 gtttaaattg aatatacaat acattaaaaa tagctatagg agtatatgca ttatctagta
      901 aagttatcaa tgcaattata gaacctatac ttattgtttt agttttccaa ctataaacta
      961 ttattaacat ttttatgaac gtcactatta atgaaaaaat cgtgaagaaa gcttcatgaa
     1021 tcagtgtcat tttaacccta gaatcaataa tttctttttt cgcaaatttt gactgacaaa
     1081 tttcatactc aaatcttttg tttacccgaa atacaaccat ttctacaaat ccacgaacta
     1141 aaaaatgatt catcttctct tcattaatta atatatgctc tttgatttga tatagagctt
     1201 ttattagtaa attagtaata ataaaaacta taaaatatcc aattaatatg gtaaacataa
     1261 cttttttatc aattctataa ataaaaacca tactaaataa aattgatgga attatttttc
     1321 taacaacggc taataaaaaa ttaaaaaata tatttctgcc agcattagct ccattttcaa
     1381 ttttttgaat taattttcca gtgcctaaca tctgatattc taagtaatct attttactca
     1441 ttttttctaa agcctttaat ttcaaatcta aaaaaaaact atgttctagt cttctacctg
     1501 gatattcatc aatatatctt aaaagacata aagtaactaa tacagttcca tagataaaaa
     1561 ttatgtgaaa atttatagta ctgttattaa atctatctat taggctctga taataattag
     1621 cactaaaact atttaaaagt tctattccta tacctagtgc taaatatata aaaactaata
     1681 acctctcttt ttttgctatt tctattaaat atttcataac tgtacaccta tccttattta
     1741 ttttacttta ttaacttaaa ataattttat agataaaatg tttctttatt tgtttaaatt
     1801 tagtgtgatt attaatcatt tcaagttaac aaaacctaaa gtttttagca gtacagttct
     1861 atttgttagc aaattattat tttactcagt acattatgct aacatataat ctaactgtac
     1921 tgagtaaata tctcgtttca tcatataaaa tctccttttt atagtttaat atatatagtt
     1981 aaatttacta tataatctga atatttattt ttctatcacc tttaccagaa ataaaatcaa
     2041 ttatttattg tataagcaaa acttcataat attttcaaca tataattatt atacagaact
     2101 cctaagttaa tttaaagtta gaatttattt ttataagaaa tgtcattgac ctacctttaa
     2161 taaaacagcc accatttttt tatgtattaa catataatat atagtaatga aaacatatta
     2221 attaaaaaat attgtataaa ttagtttatc tgtaacaaat ccagtttatg tttcaacaag
     2281 cacgtaagac ttcttgaaat ttaatctgct tcctttaaat atctattact tgttttaagc
     2341 ataagtttac aatcttctat aacatttatc atttcttcag atttctctga cgtacttaaa
     2401 atacaagttg ttacattgtt tttctattta attagtaatg tatcatgtaa aaaagaagca
     2461 taaatgagtt tactttatac aaacttcatt tatgctccac tcatatacct atcatagcta
     2521 atagaaacta ttactcatct tgaatctatt tcatatttag atatttatat ctttcttatt
     2581 ttcttaaatc aactctagct ttaaacatta aaccccttaa atcttcacaa aatctcttcc
     2641 tatacagact tactctttgc cttacatatc atctgagtca tagtacccat agggcaataa
     2701 acacaccatg aacgaggttt aaacaatatc atagtaatca aaccaagaac agttgatgta
     2761 agcataacac tataaaaacc aaatgcaaac tgtaccaccc aaggtgaaac taaagttcca
     2821 tgatacgccc attgccaagg catttttata gtccacaaca aagtcactac ttctttaaaa
     2881 tttctacttc cttcaaacac taaataagtt gaaaaaagca tattggcaaa cattaccata
     2941 aaaaatgtca aaaacccata tctaaaccac ttacttctaa taaatttagg aatatctcta
     3001 tttcttgaca gcttcaattt atttccaagc aaattaaaca gttgccctct tccacaatac
     3061 ttattacagt aagctttatt tcccttaaca atagaaatag ctagtggaac aaagaaacaa
     3121 attagcccaa tccaagcgaa aataatattt acaaatccca ataccaaata tattgaagaa
     3181 aaaatccata aatagtcata ccaatgtttt ttattattca tgacacttac cttcttcctc
     3241 ttttaatatt gttataatct caattacaga tgctggacat atcttttcac aaatcccaca
     3301 tccaacacat aaatctctat taatttttgc actaatgcca catggaactg agatagcact
     3361 tcttggacat gcttttatac agctaccaca agcaacgcac tcatttgcta aaatatttgc
     3421 atacttcttt tttttattag acataataac ctccctatat tattaatcta taagaattat
     3481 atcaagatac ttacttttta tctgtgactt aatcacataa aacctcaata ttaaaaatca
     3541 cactctaaat acaaaggagt ttcaaataaa aaacgatatg aagtcattaa gtttagcttc
     3601 atatcgcctt ttcttttgtg tatctatata aatatttatt atctaatatt taatatatct
     3661 ataatatttt cttatacagc tctataattt tacacctaat catattctat tagtaacagg
     3721 ttaataccca tctaaaacta taactttatt cacaatctta ttctattagc cacaagttaa
     3781 actcatattg aagtttatct ttagttacac tcttactcta ttaatcacaa gttaagccca
     3841 tattgaagtt tatctctatt tacactctta ctctattaat cacaagttaa gctcatattg
     3901 aagtttatct ctatttacac tcttactcta ttaaccacaa gttaaactca tattgaagtt
     3961 tatctctatt tacactctta ctctattaat cacaagttaa gctcatattg aagtttatct
     4021 ctatttacat tcttactcta ttaaccacaa gttaaaccca tattgaagtt tatctctatt
     4081 tacactctta ctctattaac cacaagttaa gcccatattg aagtttatct ctatttacat
     4141 tcttactcta tcaatcatag gttaagctca tattgaagtt tatctttagt tgcaccttac
     4201 tctattaatc acaagttaaa cccatattga agtttatctt tagttacacc ttactctatt
     4261 aaccacaagt taaacccaca ttgaagttta tctctattta cactcttact ctattaatca
     4321 caggttaaac ctattataat cttaacttta ttcacaattt tattctatta gccacaggtt
     4381 aaatctatta taatcttaac tttattcaca tattacatca ttaatcgcat atcaagattt
     4441 tataataagc tttaactaaa cacacgattt taccttattc gtatagttta atctattaaa
     4501 ttattatata atcttaagca aacatacaac tctacactat taattatagc ccctcctttt
     4561 aaatactcat aatcttatac acaaccttac cttattaatc acacatttaa ctcatatata
     4621 tcatcaattt tattcacaaa atcatgctgt taatcacact tatactcctc tataatctta
     4681 aacttataca caaattagcc acaattttat ttcaactata ataacttcta tttcagaagt
     4741 atatcacact tgtattctcc aaaaatatct atttttttct aacaatatgc ctgacattaa
     4801 taacactcat ttcaaacatc ctcgctaatt ccatataatt tttcccatta aacaatttaa
     4861 tcataagctc atttctagcc tcttttaatg ccccttccag tgttttaata taaaaatatg
     4921 ttcccccact ttgttgacac aattcaaggt attccaataa actatactta tgtaactcct
     4981 ttggaatact tacttctatc ttgtgttctt caagtaattc tataattttc gttaattcca
     5041 acatattttc acctcatatt ttataatcta tttgctattt cctgactttt aataagcttg
     5101 ttattactac tttattgacc taataattta gttcttgaaa atgtaactta tccccaaagt
     5161 aacaaaaatg cttatgccta gtctgtccat ctctacactt cgcaactatt aaatcaacca
     5221 tcttaattcc cctgtattct gatgctctaa ctgcctcctc actttctcca atatctctca
     5281 ctgcttcttc ataatcactc ccctttaatt gatgtatata aaccacattg ttgctatcgt
     5341 ggtagatggc tttgctatcc ctcataggtc tatctccata aggtcttgaa tctttcattt
     5401 catcatttaa ctgacttaat tggattacag gtatattaaa atctaaagtc atatttttaa
     5461 gttctctcga aaaagtagct acctcccttt ctctcttatc catgcttttc tgagatgtaa
     5521 ggagttgcac ataatccact attaataaat ctggctttac ctgccttatc ctctttctaa
     5581 ttgcactaat tgtatctatc ttatcattaa tataaattaa gttattttcg cttaaatcac
     5641 ctatagcatt tacaataagt ttccaatcat tttcatctat ttctttagat ttcatattcc
     5701 ttgtacttac accagttact ctgcatatat ttctcataaa tacttgctca ctggtcattt
     5761 ctctacttat aaataaagtt tttttacctt gcttaaatga atttaacatt atttgaagtg
     5821 ccaaagcagt tttcccaacc cccgatttag ctgctattgt ggttagctct cctttaaaaa
     5881 gacctcctat agtagtatca agtaatttta taccaaattt aaatccaata tcttttttgt
     5941 tttctaaaaa atcaagcacc ttccctgcta tactatttac atcatcattt tcataagtat
     6001 ccttgtccaa aatctccttt atattacttt caaatttgta aatacaagta tcgatatttt
     6061 ctccaaggtt taggctgtgt aaaaggtttt ggcagttttg atttatgctt cttctagcta
     6121 aattttcttt taaaatttta atatgaccat caagaccaaa attctgaccc caagtaatta
     6181 gattagtcac atcactcgtt tttattgcta gagattttct atctatcttt gatttcacag
     6241 tggccacatc aatcactatg ttttcttttt taagttcttt cataatttta aatatctcaa
     6301 gacatatatc attcataaac atgttttcat ttaattcatc tagcttatag cttaatttat
     6361 tgtctaaaag aattgtgcct aaaatagact tctctatttc aacatctttt gatttaccca
     6421 tataaattaa tctctctttc cttataagtt tttatatttt gatttttaaa tacattatca
     6481 attataaata cattatttgt tatgactcac tatttgttat gactatatta ttcgtcatga
     6541 tatactacaa attattaata tactatttat tctgatacat ataatttact acataatagc
     6601 aatatcttat ttgatataac ttactaccaa ttattaatac attgttcaat ataattcatt
     6661 actcgatagt aatatcttat ttgatataac ttactgccaa ttattgatat atcgttcaat
     6721 ataattcact acctgatagt aatatcttac tt
//
LOCUS       DAMJYN010000139         6744 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.145, whole genome shotgun sequence.
ACCESSION   DAMJYN010000139 DAMJYN010000000
VERSION     DAMJYN010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6744)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6744)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6744
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.145"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(64..672)
                     /locus_tag="PC466_003447"
     CDS             complement(64..672)
                     /locus_tag="PC466_003447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HDF2770798.1"
                     /translation="MEKDFFRKNGIDLAKSILGKYLIRKYENKVIVTKIIETEAYMGV
                     NDKGAHVYGNKKTDRTKPLYLDGGHIYVYLIYGMYNCLNLSANIENVPECVLIRGVEP
                     ITSLDEISMNRYNKAYTELSKYQVKNITNGPGKLCKALKIDRSLNSKSIMGEELYISD
                     FYYDDKGKKVFSKDELDIKTSKRINIDYAEEAKDFLWRFYIE"
     gene            complement(781..3519)
                     /locus_tag="PC466_003448"
     CDS             complement(781..3519)
                     /locus_tag="PC466_003448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing sensor histidine kinase"
                     /protein_id="HDF2770799.1"
                     /translation="MESKGTLSKNKVYILANGLFLVIALLNINLYTVSINMYRIILLW
                     IFGYSIVYISSFKTDEFINILKVGCLVLVFVSILGVVNLKIQKFQIVLLNLSIINMST
                     FIYLTISKVKKLRISPILIFYSAFVILDYFIRNIFSDINWNMIIILINICISMFNLLY
                     LLNKLDSNIEHYKLIKDLTYFVFFTTIICFVAISKINIVDSDRLIGVIYLLLCNHTYY
                     VYVYSLNNRVVYPYYELDSINKKLSKKSEQLGKINLAIEKDMIIQRTLKNYIDQRKEL
                     LRQALDTIPNVWIVTDYDFNISYTNNKFKDEFSKDMNNYYKILTFIKEDEKVAEKLKK
                     FDNDISIIDKLVELNDKIYLLSLSNNKDESNYLISLNDITNEIKIDEEIRNINKDYEN
                     IILNIPSPILVRSAEGGIKKNKVISINKKYEKSFKCVSSDLVDMTLEQYFETFNIDFF
                     DNRKFKRLNLTQEKKAEIVSYNDTANCIVNFVMSDSEGEEHVEEVRVGDYWSDNKLFK
                     LLTFRDITKEINILRTVNEQKIIYEKLLDVIPEAIFLEDLSTSRVLYTNRAFRELFGI
                     SSDVLGVTTQKYRNILVKKYINNLNIGEREKSIHIVNENNHIKEVKMISRTLYFGQKR
                     SRVRIIKDLSVQRESERLKKALIKQRQYDQMKMEFYANISHELKTPLNNIYSSVQLIE
                     NLYKKGKIIDFQDILKEHIKITKQNMFRLLRLIDNIINISQVKSDIYKIKAVNFDIID
                     ITERIVTSISSYAKSKGIDLIFDTDEETVMVGLDPESIERIILNILSNAIKFTLEGGE
                     ILVGIYKKDETVEIIIKDTGVGIDKEKLNDIFNRFKQIENSGISNEFGSGIGLCLTKS
                     LIEIQNGKIYIDSKVGEGTNVKVIFPIKEVVEEVYDNSNYNDNIEKFEIEFFDIYK"
     gene            complement(3667..4458)
                     /locus_tag="PC466_003449"
     CDS             complement(3667..4458)
                     /locus_tag="PC466_003449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011987989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HDF2770800.1"
                     /translation="MKLKKLLSVALVSAIAISAVGCSNKEDKKILVGASSNPHAKILE
                     VAKPLLKEKGYDLEVKIFDDYVLPNTALDEGSLDANFFQHIPFLEETVKEKGYKLTYT
                     SKVHIEPMGFYSEKVKSLDELKDGAVIAVPNDATNGARALKLLAKNKLIEVKDGELIT
                     KKDITKNPKNIVIKEMNAEQLPTVLKDVDGAVINSNYALTANLNPTKDAIVIESSDSP
                     YVNIIACRENNKDSDKIKALSEAMNSKEVKKFIQDEYKGSIVPAF"
     gene            complement(4494..5150)
                     /locus_tag="PC466_003450"
     CDS             complement(4494..5150)
                     /locus_tag="PC466_003450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2770801.1"
                     /translation="MNSLIDFLTTLFPNALLQTLYMVIVPTIVATILGFILAIILVVT
                     KPDGLKPNSTINSALGFIVNIFRSFPFMILIVAMIPITRLIVGTSIGETAAIVPITIG
                     AAPFIARIIESSLNEVDKGLIEAAKSFGATKRQIVFKVMIKEAMPSIVSGITLSIISI
                     LGYTAMAGAVGAGGLGNIALIYGYQRFDTAVMVYTVIALIILVQIIQGVGNLAYKKLK
                     "
     gene            complement(5143..6108)
                     /locus_tag="PC466_003451"
     CDS             complement(5143..6108)
                     /locus_tag="PC466_003451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HDF2770802.1"
                     /translation="MISIKNVNKYYGKIQVLKDVSIEIESGEIFGIIGHSGAGKSTLL
                     RCINGLEEYQEGSVLVSDKEVKSLNEKQMRDLRKELGMIFQHFSLLERKTVFDNVALP
                     LECFGYSKAEIKKRVLELLEVVGISEKKNDKPRNLSGGQKQRVAIARALALNPQVLLC
                     DEATSALDPNTTKSILSLLEDINKKLGITIIVVTHQMEVIKQICGRVAIMENGEVLEV
                     GDTEEIFLRNTKGLRKLIGEESIILPKGTNIKILFPKDISNEAIITTMARELNIDVSI
                     IFGKLEQFKDDILGSLIINISDKSGEHVKQYLTSKGIRWEEMINE"
     regulatory      complement(6214..6320)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
BASE COUNT         2148 a         1142 c          616 g         2838 t
ORIGIN      
        1 aaaaataaga tacataccta taaaatacct tcctatagat acatatctta cctatataaa
       61 aacttattct atataaaaac gccataaaaa atcttttgct tcttctgcat aatctatatt
      121 tatacgttta ctagttttta tatctaactc atctttacta aatacttttt ttcctttatc
      181 atcataataa aaatcactta tatataattc ttcacccatt atactcttac tatttagact
      241 tctatctatt tttaaagctt tgcaaagttt tcctggtccg ttagtaatat tttttacttg
      301 atatttactc aactcagtgt aagctttgtt gtatctattc atagatatct catctaaaga
      361 agttataggc tctacccctc ttattaatac acactctggc acattttcta tatttgcaga
      421 taaatttaag caattataca taccataaat taaataaaca tatatatgtc caccatctaa
      481 atataatggc ttagttctat ctgtcttttt attgccatat acatgtgctc ctttatcatt
      541 tacacccatg tatgcttctg tctctatgat tttggtaaca attactttat tttcatattt
      601 ccttattaga tatttaccta atattgattt ggctaaatca attccatttt ttctaaaaaa
      661 atccttttcc aaaatttcac ctcataaaat ttatttaaaa cgcatcaaat acaactaaag
      721 taataaataa aattaactct tattaatgtg atatatataa acaataaatt tagccattta
      781 ttatttatat atatcaaaaa attctatctc aaacttttca atattatcat tgtaatttga
      841 attatcatat acttcttcaa caacctcttt aattgggaat ataactttta cattagttcc
      901 ttctcctacc ttactatcta tgtaaatctt cccattttga atttcaatca atgattttgt
      961 aaggcataaa cctataccac ttccaaattc atttgatata ccactgtttt caatttgttt
     1021 aaatcgatta aatatatcat ttaatttttc tttgtctatg cccactccag tatcttttat
     1081 aattatctct actgtttcgt cttttttata tatacctaca aggatttctc ctccttctaa
     1141 agtaaatttt atagcatttg ataatatatt tagtattatt ctttctatag attctgggtc
     1201 aagccctacc ataacagttt cttcatccgt atcaaaaatt aaatctattc ctttagactt
     1261 agcataacta ctaatagatg taactattct ttctgttatg tcaataatat caaaattaac
     1321 tgctttaatc ttatatatgt ctgacttaac ttgagaaata tttattatat tatctattaa
     1381 tctcaataat ctaaacatat tttgtttagt tatttttata tgttctttta gtatatcctg
     1441 aaaatcaatt atttttcctt ttttataaag gttttcaata agttgaactg aactatatat
     1501 attatttaaa ggtgtcttaa gttcatgaga tatattagca taaaactcca tcttcatttg
     1561 gtcatactgt ctttgtttta ttaatgcttt tttaagtctt tcagactctc tttgcacact
     1621 taaatcttta ataattctca ctctacttct tttctgtcca aagtataatg ttcttgatat
     1681 catttttact tctttaatgt gattattttc atttactata tggatactct tctctctttc
     1741 tcctatattt aaattgttta tgtatttttt tactaatata tttctatatt tttgtgttgt
     1801 aactcctaat acatcactag aaattccgaa caactctcta aaggctctat ttgtatatag
     1861 tactcttgat gtacttaaat cctcaagaaa aatagcctct ggtataacat caagtaattt
     1921 ttcatatatt attttttgtt catttactgt tctaagaata tttatctctt tagttatatc
     1981 tctaaatgta agcaatttaa agagtttatt atctgaccaa tagtctccaa ctctaacttc
     2041 ttcaacatgt tcttcacctt ctgagtcaga catcacaaaa ttaactatac agtttgctgt
     2101 gtcattgtaa cttactattt cagctttctt ttcttgtgtt agatttaatc ttttaaattt
     2161 cctattgtca aagaaatcta tgttaaaagt ttcaaaatat tgttctaatg tcatatcgac
     2221 taaatcactt gaaacacatt taaaactctt ttcatatttt ttatttatac ttattacctt
     2281 attcttcttt atgccacctt cagcacttct tacaagtata ggagatggaa tatttagtat
     2341 aatgttttca tagtctttat ttatatttct tatttcttca tctattttga tttcatttgt
     2401 aatatcattt aaacttatta agtaattgct ttcatcttta ttattactta aacttaacaa
     2461 ataaatttta tcatttaact ctaccagttt atcaattata cttatatcgt tatcaaattt
     2521 cttcaatttt tcagcaactt tttcatcttc ctttataaaa gttaatattt tataataatt
     2581 attcatatcc tttgaaaatt catctttaaa tttattattt gtgtaactta tattaaaatc
     2641 atagtctgtt actatccata catttggtat tgtatccaga gcttgtctaa gtaattcttt
     2701 tctctggtct atgtagtttt ttaatgttct ttgtataatc atatcctttt ctattgctaa
     2761 atttatcttt cctaattgct ctgacttttt acttaatttt ttattgattg aatcaagttc
     2821 ataatatgga tacactactc tattattaag actgtataca tatacataat aagtatggtt
     2881 acataatagt aaatatatta ctcctattaa tctatctgaa tctactatat taatcttaga
     2941 aattgctaca aaacatataa tagttgtaaa aaaaacaaaa tatgttaaat cttttattaa
     3001 cttatagtgc tcaatgttac tatcaagttt attcaacaaa tatagtaaat taaacataga
     3061 tatacaaata ttaattaata taataatcat attccagtta atatcactaa aaatatttct
     3121 tataaagtaa tctaatatca caaaagcact ataaaaaatt agtattgggc ttattcttag
     3181 tttttttact ttagaaatgg ttaagtatat aaaagtagac atattaatta tgcttaagtt
     3241 aagcaataca atttggaatt tttgaatttt taaatttact actcctaaaa tacttacaaa
     3301 aactaataca agacacccta ctttcaatat atttataaat tcatctgttt taaagctact
     3361 tatataaact atagaatatc caaatatcca aagtaaaatt attctataca tatttataga
     3421 aactgtatac aaatttatat ttaaaagtgc aataaccaaa aataacccat tagctagtat
     3481 atagacctta ttcttactta aagttccttt agattccata ttccccacca cttcttcatt
     3541 tttatatagt tttacctata aatatgttac cacaattctt ccaaaaaatt tgtcactttc
     3601 tagttataaa aaaaaatgag taaatatttt taattttact cattttgtag attttgtata
     3661 ttcagtttaa aaagctggaa ctatacttcc tttatattca tcttgtataa attttttaac
     3721 ttctttacta ttcatagcct ctgataaagc cttaatctta tcactatctt tattattttc
     3781 tctacaagct attatattta catatggaga atcacttgat tctattacta ttgcatcctt
     3841 agtaggattt aagttagctg ttaaagcata attagaattt attactgctc cgtcaacatc
     3901 ttttaatact gttggtaatt gctctgcatt catttctttt attactatat ttttaggatt
     3961 tttagttata tcttttttag ttataagctc tccatctttt acttctatca atttattttt
     4021 tgctaataat ttaagtgctc tagctccatt agttgcatca tttggcacag ctataacagc
     4081 tccatctttt aattcatcta atgacttaac tttttctgaa tagaatccca ttggctctat
     4141 atgaacttta gatgtataag taagtttata tcctttctcc ttcacagttt cctctaaaaa
     4201 tggaatatgt tgaaagaagt tagcatccaa agacccttca tctaaagctg tatttggaag
     4261 tacataatca tcaaatattt ttacttctaa atcatatcct ttttctttta acaaaggttt
     4321 tgcaacttcc aatatctttg catgtggatt tgatgaagct cctactagta tttttttatc
     4381 ctctttgttt gaacaaccta ctgctgatat tgctattgct gacaccaatg ctactgataa
     4441 taatttcttt aatttcattt ttactccccc tctttaaaat gtttataatt aatttatttt
     4501 agtttcttat aagccagatt tcctactccc tggattatct gaactaatat tataagtgct
     4561 attacagtat ataccattac tgctgtatca aatctttgat atccataaat aagtgctata
     4621 ttacctaatc ctccagctcc tactgcacct gccatagctg tataaccaag tatagatatt
     4681 attgataatg taattccaga tactattgaa ggcatagctt cctttatcat aactttaaat
     4741 actatttgtc tttttgtagc tccaaaagat tttgctgctt ctatcaatcc tttatcaact
     4801 tcatttaatg agctttctat aattctagcg ataaacggtg ctgccccaat agttattggc
     4861 actattgcag cagtttcccc tatacttgtt ccaacgatta atctagttat tggaatcatt
     4921 gcaactataa gtatcataaa tgggaaactt ctaaatatat ttactataaa tcctaatgca
     4981 ctatttattg tgctatttgg ttttaatcca tctggttttg taactactaa tatgattgct
     5041 aatataaatc ctaatattgt tgccactata gttggtacta taaccatata caaagtttgt
     5101 aacaatgcat ttggaaatag tgttgttaaa aagtcaatta aactattcat ttatcatttc
     5161 ctcccatctt atgcccttac tagttagata ttgttttacg tgctctccac ttttatctga
     5221 aatgtttata ataagtgaac ctaaaatatc atctttaaat tgttctaatt tcccaaatat
     5281 tatagacaca tctatattta gttctcttgc catagtcgta ataatagctt cattagaaat
     5341 atctttaggg aatagtatct ttatatttgt tccttttggc aatattatac tttcttcacc
     5401 tattaatttt ctaagtcctt tagtatttct taagaatatt tcttctgtat ctcctacctc
     5461 taatacttct ccattttcca ttattgctac tcttccacaa atctgcttta taacttccat
     5521 ttgatgagtt acaactatta ttgttattcc caatttttta tttatatctt caagcaatga
     5581 aagaattgac tttgtagtat ttgggtctaa tgctgaagtt gcttcatcac aaagaagtac
     5641 ttgtgggttt agtgctaaag ctctagcaat tgcaaccctt tgtttttgtc cgccacttag
     5701 atttctgggt ttatcatttt tcttttcaga tattccaact acttctaata actctaaaac
     5761 tcttttttta atttctgcct ttgagtatcc aaaacattct aatggcaatg ctacattatc
     5821 aaatacagtt tttctttcaa gcaatgaaaa gtgttgaaaa atcattccta actcttttct
     5881 taaatctctc atttgctttt cattcaatga ctttacttct ttatcagaaa caagtacact
     5941 gccttcttgg tattcttcta atccgtttat acatctcagt agtgttgatt tccctgcacc
     6001 actatgacct attattccaa aaatttctcc agattctatt tcaatactta catctttaag
     6061 cacttgaatc tttccataat acttattaac attttttatg ctaatcataa aatttcctcc
     6121 catatattct gctcagtttt tatgtttatc ctctcttatg tattacaaca aaataaaagc
     6181 ccgagtataa actcaggctt agaaagctat ttatactcat ctatcaacta tattagttgc
     6241 aggatttagc accaatgtat ataaaatata ctggttgccg ggtttcaaag ggccagtccc
     6301 tccaccactc ttgataagac gttatttaat tcaattctat tatcatttgt tgctatgtta
     6361 tatatgatat attcattaat agtatttgtc aataaattta tttaaatttt ttatttttta
     6421 ttatcgttaa ttaactattt ttaattagtt ttctagctcc taacacttta tattttaatg
     6481 tctatataac tatagaacat cattataaga aataaattaa ataacatcaa tctatctaaa
     6541 tcatctgtaa agtaaattaa gaaaattaac attttatcca aactctatcc tactattaaa
     6601 taaaataatt taaatacaat gatgattata tagctctaat actttagact ttctgaacct
     6661 cccatgacta aagtcacagg gttcctgctt catagaattt tgcatactaa aatatgtctt
     6721 actaattctc cacaggctat cccc
//
LOCUS       DAMJYN010000140         6718 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.146, whole genome shotgun sequence.
ACCESSION   DAMJYN010000140 DAMJYN010000000
VERSION     DAMJYN010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6718)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6718)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6718
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.146"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            357..1631
                     /locus_tag="PC466_003452"
     CDS             357..1631
                     /locus_tag="PC466_003452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HDF2770803.1"
                     /translation="MQFMDVSKYIEGANLKVKTKNGETVKRIYFNNSATPLVLKNVVD
                     NLNCEIPWLTYINAPGIISEKNTLKYENVRSTILKLIDGDEEKDSAIYVKNATEGINF
                     LAKFFKDENPDKFIITTAMEHMANYLPFKVNFPTKVVGITEKGELDLCQLENILKNYA
                     GNVSLVTVTGASNVTGITTPIYEIARIAHKYGAKILVDIVQVIQHKPFSMMPHECDEH
                     IDFVVFSAHKCYSPLNGGALVGPKKFFEKFNPVLYGSGSTKFVNDNKILYANVPQRFE
                     AGYPEYFGTLAMGKALNTLNKIGLNRISKYERELFLYAKEEMSKIPNIIIYGDKSNNV
                     IIPNISFNISNMYYKDVAKYLVDNFGIETGAGVVGADIYVQKLLGISPKEAYVRFMRE
                     NPVGLVRISLGMYNTFDEVDSFIHAIKTLAFK"
     gene            complement(1838..2155)
                     /gene="trxA"
                     /locus_tag="PC466_003453"
     CDS             complement(1838..2155)
                     /gene="trxA"
                     /locus_tag="PC466_003453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HDF2770804.1"
                     /translation="MVKIINNNEFINEVENKDGLVVVDFFATWCGPCKMLSPIYEALG
                     NEMVEKANFLKVDIDQSIELAQKFEVSTVPTMLIFKDGKPVDRLIGFMPKENLKNKIE
                     SYM"
     gene            2422..3174
                     /locus_tag="PC466_003454"
     CDS             2422..3174
                     /locus_tag="PC466_003454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrmB family transcriptional regulator"
                     /protein_id="HDF2770805.1"
                     /translation="MDNIINELQNIGFTKYESQIYISLLKESPLTGYEISKLSGVPQS
                     KVYENITKLLNNNIIINVGTDPIKYIPINPNELLKNKKKEFDNSMDNLKNSLQILNKN
                     KSVEYVLNIKGDKNILKKALEMIKNAKQEIIISCPYEEILELKKELLIAYKKNINIEI
                     LLLENKSLKGLDNIHTHGGNKTTLENKMLYKGIILIVDNDEILTGNLSEGSEAISIWT
                     KNSNILYIGVQYIKHEIYISEQIKGGYKNEQN"
     gene            3161..4042
                     /locus_tag="PC466_003455"
     CDS             3161..4042
                     /locus_tag="PC466_003455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HDF2770806.1"
                     /translation="MNKIKIKQVDAFTTIPFGGNPAGVVTDASNISDEIKQNVAKEMN
                     LSETAFVSESNVADFKVQFFTPGLEVDLCGHATIGTFHALLEEGRLNTNKSIFYQETK
                     AGVLSVELKEINNENIFMMEQNTPEFENLDNYRKELAQMIGVHEDRLLEYPIIKVNTG
                     LWWLVFGLKSLDDLKNISPDLNKIKKFSGDNNIIGITPFCIETIDKKCDYHLRSIAPY
                     VGVTEDPVCGTGNACVSSYIVHHNILDKTSFIGEQGNFINRPGKVYVNITRENNDITS
                     VKIGGSAYTVLSGEIMY"
     gene            complement(4268..5623)
                     /locus_tag="PC466_003456"
     CDS             complement(4268..5623)
                     /locus_tag="PC466_003456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HDF2770807.1"
                     /translation="MSSTVKKKGKFPMGFYICSTTFSFERAAYYASKYLIYIFLTTAI
                     VHGGLGIDKGQAAIMQANLVAFTYLAPIIGGYISDRWIGARYTIPIGMLIMGVGYYLG
                     SIATTVSMVNAMIILVSIGTAFFKGNVSAVNGQLFDSQEELDTAFSVQYSFVNIGSFI
                     GTIAVGILYLKTFAKNGVLGFSQCFFIAAVLCVIGAIWFIYGWRFLGNAGKRPFKEGV
                     VAEKVEEKDKSPLTSMDKKRIWAIILISFFSVIFWVFWYLTYLAVYDYGAAFVNMNVG
                     GFDVPLAWFDSLNSLVCIVLGPVLGALWFKLASRPQGDMSLFKKTGLGLIFLGLAFLM
                     LVGAEFSRGVGAPETAKASILWIIMFGILLSLGEMLFSPLGNSFVSKYAPKKLLGVLM
                     GVWTFATFIAGKGYGYIYAFTLKFDMIKVYTIIPVILFVAAILLFLSDKTLSRLVEDD
                     K"
BASE COUNT         2590 a          953 c          836 g         2339 t
ORIGIN      
        1 tctaatcaat ttctttacta tttttacaac tttattagtc atattcataa ttatttctaa
       61 ttagtgttta acattttatg taaaatttat aaaaaaatgt atataaatta aaataagtga
      121 ctatactaaa aatatgatac ggataaacaa taagttcaac ctatctcccc caaaatcaag
      181 tgagctacag tttcccccaa ctgtagctca ttttcgtgta atttaataaa catctcaaca
      241 agaattaatt aacaaaaccc cttataaaaa cataacatat attaaacaag ctcttgatta
      301 aaacttgagc ttttttaata aaaaacagaa tagtttatta gataaggggt ttttttatgc
      361 aattcatgga tgtatctaaa tacattgaag gtgcaaacct taaagttaaa actaaaaatg
      421 gtgaaactgt taaaagaata tattttaaca actctgccac tccattagtt ttaaaaaacg
      481 tagtggataa cttaaactgt gagattcctt ggcttactta tattaatgct ccaggaataa
      541 tctcagaaaa aaatacttta aaatatgaaa atgtacgctc tactatcctc aaacttattg
      601 atggagacga agaaaaggat tctgctattt atgtcaaaaa tgctacagaa ggaataaact
      661 tcttagcaaa attttttaaa gatgaaaatc cagataaatt tattattacc acagcaatgg
      721 agcatatggc taattaccta ccttttaaag ttaattttcc tacaaaagtt gttggaatta
      781 cagaaaaagg agaacttgat ttatgtcaat tagagaatat acttaaaaat tatgctggta
      841 atgtatctct cgttacagtt acaggagcta gtaatgtcac aggtataacc actcctatat
      901 atgaaatagc aagaatagct cataagtatg gtgcaaagat attggtggat attgtgcaag
      961 taattcagca taaacctttt tcaatgatgc cacatgaatg tgatgagcat atagattttg
     1021 ttgtttttag tgctcataaa tgttattctc cactaaatgg aggagctctg gtaggaccta
     1081 aaaaattctt tgaaaaattt aatcctgtac tatatggctc aggttctacc aaatttgtaa
     1141 atgataacaa aatactatat gcaaacgtac cccaacgttt tgaagcagga tacccagagt
     1201 attttggaac tcttgcaatg ggaaaagcac tgaacacttt aaataaaatt ggtctaaaca
     1261 gaatttcaaa atacgaaaga gaattatttt tatatgctaa agaagaaatg agtaaaatac
     1321 ctaatataat aatatatgga gataaatcaa ataatgtaat tatcccaaat atatctttta
     1381 atataagtaa tatgtattac aaagatgtag caaaatattt agttgataac tttggaatag
     1441 aaactggagc tggagtagta ggtgcagata tttatgtaca aaaattatta ggtataagtc
     1501 caaaagaagc atacgtcaga tttatgaggg aaaatcctgt aggtcttgtt aggataagct
     1561 taggaatgta caatactttt gatgaggtgg atagctttat acatgctatt aaaactttgg
     1621 cttttaaata agctttttct attctttttt atcaataaat agagagtagt tttgttttca
     1681 caaaaaaaca aattatatca acagtcaatt tcattagcaa ttagacactc atttgtaact
     1741 atacaaacta ttttacacta tacaaataaa aaactcatta caatgagttt ttttgtttat
     1801 atatgatatt tattttaatt acttcaattt actttaatta catatatgat tcaattttgt
     1861 tttttaaatt ctccttaggc ataaaaccta ttaatctatc tacaggtttt ccatccttaa
     1921 atattagcat agttggtact gtagatactt caaatttctg agctaattct atactttggt
     1981 ctatatccac cttcaagaag tttgcttttt caaccatctc atttcctaaa gcttcatata
     2041 ttggtgatag catcttacaa ggtccacacc aagtcgcaaa gaaatctaca actactaaac
     2101 catctttatt ttctacttca tttataaatt cattattatt tattattttt accataatat
     2161 acatctcctt tattatcttc ttgatactaa tatactacgc cctatataac agttcaatta
     2221 ggcacttttt tgtaaccgcc tatttttaat agatttaata ttatgataaa tagatttata
     2281 agattaaata tttataagac taaatatttc tgatatattt tatttttttc ttaatatagt
     2341 tgacattttc tcccttaaat tataaaatca aattaataac tacataggta gttactaatc
     2401 ttttatcaaa ggagtttcta tatggataat ataattaatg aattacaaaa tataggattt
     2461 actaaatacg aatctcaaat atacatatca ttattaaagg aaagcccttt aacaggatat
     2521 gaaataagta aattatcagg tgtaccacaa tcaaaagtct atgaaaatat aacaaagcta
     2581 ttaaacaata atataattat caatgttgga actgacccta ttaagtacat acccataaac
     2641 cctaatgaat tattaaaaaa taagaaaaaa gaatttgata attctatgga taatctaaag
     2701 aatagcttac agatattaaa taaaaataaa agtgtagaat acgttttaaa cataaaagga
     2761 gataaaaata tattaaaaaa agcattagaa atgataaaaa atgcaaaaca agaaattata
     2821 atttcttgcc cttatgaaga aattcttgaa ttaaaaaaag aactcctaat tgcttacaaa
     2881 aaaaatatta atattgaaat actactttta gaaaacaaaa gtctgaaagg tcttgataat
     2941 attcatactc atggaggtaa taaaactaca cttgaaaata aaatgcttta caaaggaatt
     3001 attttgattg tagataatga tgaaatattg acaggaaact tatcagaagg cagtgaggcc
     3061 atttcaattt ggacaaaaaa ctctaacatt ttatatattg gagttcaata cataaaacat
     3121 gaaatttata tttcagaaca aataaaagga ggttataaaa atgaacaaaa ttaagattaa
     3181 acaagttgat gcttttacaa ctataccttt tggtggaaat cctgctggtg tcgttactga
     3241 tgcctctaac atttctgatg aaattaagca gaatgtggct aaagaaatga atttatcaga
     3301 aactgcattt gtttcagagt caaatgttgc agattttaag gtacaatttt tcacaccagg
     3361 tttagaagtt gatttatgtg gtcatgcaac aataggtact ttccatgcac ttttggaaga
     3421 aggaaggctt aatactaata agagtatatt ttatcaagaa acaaaagctg gtgtattatc
     3481 tgtagagctt aaggaaataa ataatgaaaa tatatttatg atggaacaga atacacctga
     3541 atttgaaaat ttagataatt acagaaaaga acttgcacaa atgataggtg tgcatgaaga
     3601 tagacttctt gaatatccta ttataaaggt aaatactgga ctttggtggc ttgtatttgg
     3661 tctaaaatct ttagatgatt taaaaaatat ctctccagat ttaaataaaa tcaaaaaatt
     3721 tagtggtgat aataatataa ttggtataac tccattttgt atagaaacta tagataaaaa
     3781 gtgtgactac catttaagat ctatagcacc atatgttgga gttacagaag accctgtatg
     3841 tggaactggg aacgcttgcg tatcatctta tatagtacat cacaatattt tagataaaac
     3901 tagttttatt ggtgagcaag gtaactttat aaacagacct ggaaaggtat atgtaaatat
     3961 aactagagaa aacaatgaca taacttctgt aaaaattgga ggaagtgctt atactgtttt
     4021 aagtggtgaa attatgtatt aatcccatac ctaataaaaa caaataaaaa tactagctaa
     4081 ctaaagctag tatttttatt tgttattttt atttaataat cacactctaa caaatattat
     4141 aattatatat atcataatat tgtatttaga agtaaaattt tatttttatt attaattagt
     4201 tataaatcaa tctaatacaa cataattaca gtagattaat ctataaaaca taataattac
     4261 ttactgatta tttatcatcc tcaacaagtc tacttaatgt cttatcagat aagaataata
     4321 atatcgctgc aacaaatagt attactggaa ttatagtata tactttaatc atatcaaatt
     4381 taagagtaaa tgcatatata tatccatatc ctttaccagc tataaaagta gcaaatgtcc
     4441 atactcccat aagaacacct agaagcttct taggtgcata cttacttaca aaagagttac
     4501 caagtggtga gaataacatt tcaccaagac ttaaaagaat accaaacatg attatccata
     4561 gtatactagc tttagcagtt tcaggagctc caactcctct tgaaaattct gcaccaacaa
     4621 gcattaagaa tgcaagacct aagaatatta atccaagacc tgtcttttta aataaactca
     4681 tatctccttg tggtctacta gcaagtttaa accataatgc tccaagaact ggtcctaata
     4741 ctatacatac aagtgaattt aatgagtcaa accaagcaag aggaacatca aatcctccaa
     4801 cattcatgtt tacaaatgct gcaccataat cataaactgc aagataagtt agataccaga
     4861 atacccagaa aattacagag aagaatgata taagtataat agcccaaatt ctcttcttat
     4921 ccatgcttgt aagaggagac ttatcttttt cttcaacttt ttcagcaact acaccttctt
     4981 taaaaggtct ctttcctgca tttccaagga atctccatcc atatatgaac catattgcac
     5041 ctattacaca aagtacagct gctataaaga aacattgaga aaatccaagt acaccatttt
     5101 ttgcaaatgt tttaaggtaa agaataccaa ctgctatagt accaataaaa gaacctatat
     5161 taacaaaaga atattgtact gaaaatgctg tatcaagttc ttcttgacta tcaaaaagct
     5221 gtccatttac cgcagatacg ttacctttaa agaatgcagt accaatcgaa actaagatta
     5281 tcattgcatt taccatagaa actgtagttg caatagaacc aagatagtaa cctaccccca
     5341 tgataagcat acctataggt atagtatatc tagctcctat ccatctatct gatatatatc
     5401 ccccaattat aggtgcaagg tatgtgaatg caacaaggtt ggcttgcatt atagcagctt
     5461 gtcctttatc tattccaaga ccaccatgaa ctatagctgt tgtaaggaat atatatatta
     5521 agtactttga agcataatat gctgctcttt caaatgagaa agttgttgag cagatataaa
     5581 atcccatagg aaatttaccc ttctttttta ctgttgagct cataatttta aatcctttct
     5641 taattgtatt tttatttttt acgttttgtc caaattcttt cttttatgaa agatataata
     5701 ttattatttt gtaaaacaat ttgtaattat tattaagata attgcgcatt tatttgtaga
     5761 gtacatattc tcatggaata aaattaatac acttcttaat cataaattta aattatataa
     5821 attcactatt ttcagatata gttataaatt aatatattct catctaatac catgaaaaaa
     5881 ccttcgccat atgcaattct tattttttac gtgatagtat tttacaaact aaaatccccc
     5941 ttttgtagca acttctgtaa ttacatttta gtgctttttt aaaggagtct cgaataaagc
     6001 aacatatatt ttgttcaaat aatgttttta tttacttttt aaatttatat attacttcac
     6061 tcaaccaatt ctcaacttaa ataaataaac tactatctat tcacagatta gacctatttc
     6121 ttacacatta gtttataata aacactgtga atctaaacat aaaaactgtt attttaaagt
     6181 aattacccat atattcgctt tgatactatt tattgaggtt atactcttta tttataatat
     6241 attatttata aaatacctca aaatatatta ttaataaaat acctcaaact gaaaactttt
     6301 tcacgaatat ttatttttca cctccccttt tttattttac catgtaaatc gtaccataaa
     6361 tatgcactta tatgcaagaa aaaaatctat taatcgacag taaataatta gaaaaattta
     6421 aattatattt gttaagtgta ttatataaaa tatttcctat gaaaatataa attaaattaa
     6481 tgttcagaat agtttttaga tatgaaatct tgattttttt attactttac ttatttgctc
     6541 aaatatattt ttgtatgcag tatataataa tcaaattata cacttcttat aactgcgttg
     6601 atttgaaaat aatattaata gttaatagaa gaaaaaattt aaattaattt ttaaaaaatc
     6661 tattaagtta attgaatact tttttatgta tttaattaat tttataaatt caattatt
//
LOCUS       DAMJYN010000141         6601 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.147, whole genome shotgun sequence.
ACCESSION   DAMJYN010000141 DAMJYN010000000
VERSION     DAMJYN010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6601)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6601)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6601
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.147"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            9..911
                     /locus_tag="PC466_003457"
     CDS             9..911
                     /locus_tag="PC466_003457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HDF2770808.1"
                     /translation="MLPQDYYGLIVILGVILGVMGAFYNWFTLYVQSLYKKIPKIATF
                     GKLLIPFIMAGILGIVMPDVLGSGHNLVEELTSHEYIFGMVVLIFVIRFIFSAVSFGS
                     GAPGGIFFPLLVLGAFIGGIFGMVGVKVFGMNPDYVNNFVLLAMAGYFTAIVRAPLTG
                     IILIFEMTGSVSQMLSLSVISIVAYIVATLMKSKPIYESLLERLLEKNGEPVHKERGE
                     KILDQFSVMFGSPVANKAIQDVQWPENCLLVAIQRGGEEIIPRGKTILRPSDVIVTMT
                     DERDSGAVYDKMENLCKEHTSHIF"
     gene            1520..2533
                     /locus_tag="PC466_003458"
     CDS             1520..2533
                     /locus_tag="PC466_003458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HDF2770809.1"
                     /translation="MVSSFLNDIFRTILVSCIFIVILLVFRITLFKTFSKKFNYYIWL
                     IVIIKLSLPFMNYTFIFNESKYNGNINKISLGNFNSISIVYSTVLVSVWIAITIFYLV
                     YTLLKYIKLKNMINDLSYDVEDDKIKNLYENLLKELKINKKIRLKYSYEVESPVFFNS
                     CVILPPCDYTLKELNWIFRHELMHFKSKDLYIKYLVIFLKCVYWFNPFVYIMEKFIDL
                     DCEFYCDERVLKNCTIEEKQDYALTIISAMRKGSNSSNKFVAGLHKESDIKKRVFSMF
                     NEKYRNGILIAVILCLLSSITYFEIDLITTKSIFYPLSKQTPIENRTNSKPTYQINVY
                     IDN"
     gene            2889..3458
                     /locus_tag="PC466_003459"
     CDS             2889..3458
                     /locus_tag="PC466_003459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrpB family protein"
                     /protein_id="HDF2770810.1"
                     /translation="MKKKLEDMTLEELWNLFPIFLTTHKECWKNWFKEEQYRLTGILP
                     MQKIVRISHIGSTSVSTIYAKSIVDILIEIIPDYNMKDIKDLIESNGYICMSESSSRL
                     SLNKGYTVDGFEERVFHLHIRYVGDNDELFFRDYLIDHPDVAKEYEKLKLDLWKKYEH
                     NRDAYTDSKLDFVREFTEKAKVLYSNRYN"
     gene            complement(3795..5132)
                     /locus_tag="PC466_003460"
     CDS             complement(3795..5132)
                     /locus_tag="PC466_003460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HDF2770811.1"
                     /translation="MDTYSLISTSINFILILINIFIAFFLYKLTSYFIDFRNHWIFKI
                     ILILGYSIISQMIIWLSDPVNILFTLFGYFILLIICSKSKLIPIISVVMILYPIIIGL
                     NFLFINNPIYEELIHSKEYILILSIVQIISALIKLLFWFLIHIFLKNRLVNIKQYLSN
                     KIWIFIDMVCISSFLSILIAIILPPTNLIPMGSNKNIILGNLPYGTYLIILSAILANI
                     GVILLLQPLIENVKMKIEKQANHLKEKYYNLLENQQIQIRKMRHDMNNHFQMIESYLE
                     IEDIAGAKKYFNQLKIGIGTLSGKQFCKNQALNSILNLRHTSLEENGVDVHFNIDIDN
                     HLGIEPIDLCTIFSNSLDNAIEASLKIPDLSNRKVVLKARCEKEYFSYLLTNNKVNPI
                     NRKQELFISDKKDSNSHGYGIENIREIVNKYNGKLDISYTENEFSLFLYIRLF"
     gene            complement(5572..6282)
                     /locus_tag="PC466_003461"
     CDS             complement(5572..6282)
                     /locus_tag="PC466_003461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2770812.1"
                     /translation="MTSICICDDEKQQRNMLNKIITREMDLWGYPYQIKEYSNGESLV
                     YNLEHENYYIDIIFLDIELEKSNGVDIAKTIRKHSKDTIIIFVTGFSDYVFHGYDVGA
                     LNYILKPYKTEKICKVLKEALKKLEQWKENFITVHIGTNLCKINTKDILYFKSELRKL
                     TVVTFDKTLEYYGKLNDMETVLPSNFIRTHQRYIVNLNHVDSITQTYAKVQNEKIPIS
                     RKKYQEVVGKFTRYMLEP"
BASE COUNT         2444 a          693 c         1000 g         2464 t
ORIGIN      
        1 ttggaaatgt gttgccacaa gattattatg gattaatagt gattttaggt gttattcttg
       61 gagttatggg ggcattttac aactggttta ctctatatgt gcagtcttta tacaagaaga
      121 ttcctaaaat tgctaccttt ggaaaactgt tgattccatt tataatggct ggtattcttg
      181 ggattgttat gcctgatgtt ctggggagtg gacacaattt agttgaagaa cttacaagtc
      241 atgaatatat ttttggaatg gttgttttga tttttgttat acgttttata ttttcggctg
      301 ttagttttgg gtcaggtgca ccagggggaa tattttttcc attgcttgtt ttaggagcat
      361 ttataggtgg aatatttggt atggtaggtg ttaaagtttt tggaatgaat cccgattatg
      421 taaataactt tgtgcttttg gctatggcag gatattttac agctattgtg cgtgcccctt
      481 tgactggtat catattaatt tttgaaatga caggttctgt tagtcaaatg ctttcactat
      541 cagtaatttc aattgtggca tatattgtgg ctacacttat gaagtctaaa cctatttatg
      601 aaagtcttct tgagaggtta cttgaaaaaa atggagaacc tgtacataaa gagaggggcg
      661 aaaagatact agaccagttc tctgttatgt ttggctctcc tgttgcgaac aaggcaattc
      721 aggatgtaca gtggcctgaa aattgtcttt tggtagcaat tcaaagaggt ggagaagaaa
      781 ttattcctag aggtaagaca attcttagac caagtgatgt aattgtgact atgacagatg
      841 agagagatag tggtgctgtg tatgataaga tggaaaattt gtgtaaagaa catacgtcac
      901 atatttttta gggataatga tgaatgttta ataatgatag aatatttaat gaagatttga
      961 ttaaaaaatt ggtaatttga aagagagtta aggaattaat agaaaatgaa aatgtgatat
     1021 cttagatgta aaagagtttg aagaaaataa ttgtatatat ttgttaatga gattatatgg
     1081 actaatggta tatttatact gtgctaaaag ttgcactatt gtatgaggaa tgggaataaa
     1141 gggtttgaaa aaataggtag aagatttttc agatattctt attgggatat tttaattaat
     1201 atattttaat tgcgatattt tgggaagaat agaatttatt tataaatgaa aataattaaa
     1261 aggggttaag gttgtattag ccccttttgc ttatagagtt tggaaatggt atcttgatag
     1321 cagttgtttt atgcttatta tattttatta catattttaa aattaacctt atcactccta
     1381 aatcattatt ctatcaactt ttaaaacact ttcaagacaa tcacctattg aaaacaaagt
     1441 taattaaaaa cctacatatc agtttagtat tcgtgtagat gattatataa atataaaagt
     1501 ataagaaagg tgagtatctg tggttagttc atttttaaat gatatcttta gaacaatttt
     1561 agtaagttgt atttttatag ttattttatt agtctttaga ataactttat ttaagacttt
     1621 cagtaaaaaa tttaattact atatatggct tattgtgatt attaagctat cattaccatt
     1681 tatgaattat acttttatat ttaatgagtc aaaatataat ggtaatatta ataagataag
     1741 tttaggcaat tttaatagta tttctattgt atatagtact gttttagtct ctgtttggat
     1801 tgctattacg atattttatt tagtttatac tttattgaaa tatattaagc ttaaaaatat
     1861 gataaatgat ttgtcttatg atgttgagga tgataagata aaaaatcttt atgaaaattt
     1921 attaaaagag cttaagataa ataaaaaaat acggcttaaa tattcatatg aagttgaaag
     1981 tccagtattt tttaattcgt gtgtcatttt accaccatgt gattatacat taaaagagtt
     2041 aaactggata tttaggcatg agttgatgca ttttaagagt aaagaccttt acattaagta
     2101 tttggtgata tttttaaaat gtgtttattg gtttaatcct tttgtgtata taatggagaa
     2161 gtttatagat ttggattgtg aattttattg tgatgaaaga gttttgaaga attgtacgat
     2221 agaagagaag caggattatg cattgacaat aattagtgca atgagaaaag gttcaaatag
     2281 ttcaaataaa tttgtggctg gattacataa ggagtcagat attaaaaaaa gagtgtttag
     2341 tatgtttaat gaaaagtaca gaaatggtat tttgatagca gttattttat gtttattatc
     2401 ttctattaca tattttgaaa ttgatttaat tactactaaa tcaatatttt atccactttc
     2461 aaaacaaaca cctattgaaa atagaactaa ttcaaaacct acatatcaga ttaatgttta
     2521 tatagataat taaaaaatac aaagtttaac aagagattaa tataaataat tttaataagt
     2581 atctttcaca tatgttaaat ttactttaat tatattaaag ccaatgaatt attctttaga
     2641 agctccaatg ccagtaaata caggtaaaga aaaatctttt actacaattg taaattaaaa
     2701 aatattctaa tatttaaaga aatgcaaaag tgtaagaagg gtaaaaatct gttataatac
     2761 attaaaaact aaatttagaa aaatttacat aattagaaaa atgatttgat aaaaaataaa
     2821 gttaaatatt aactaagtaa atttgaaaaa gaaaaaatat aaagtacaaa tttaaaagga
     2881 ggtaactaat gaaaaagaag ttggaagata tgactttaga ggagttatgg aacttgtttc
     2941 ctatattttt gactactcac aaagaatgtt ggaaaaattg gtttaaagaa gaacaatata
     3001 gactaactgg aatattgcca atgcaaaaaa ttgttagaat aagtcatatt ggaagtactt
     3061 ctgtgagtac gatttatgcc aagtccattg ttgacatact gattgagata attcctgatt
     3121 ataatatgaa agatattaaa gatttgattg agtcgaatgg atatatttgt atgtctgaga
     3181 gcagtagtag gctttcactt aataaagggt atacagtaga tgggtttgaa gaacgcgttt
     3241 ttcatttgca tataaggtat gtaggtgata atgatgagtt gttttttaga gattacttaa
     3301 ttgaccaccc agatgttgca aaggagtatg aaaaacttaa gttggacctt tggaagaagt
     3361 atgagcataa tcgtgatgct tatacagata gtaaactaga ttttgttagg gagtttactg
     3421 aaaaggcaaa ggtgttgtat tctaatagat ataattagaa ataggtacaa ttagatattt
     3481 atcttatata tcgtattata ttttttaaga aagtaattaa tagaaaaagg ggttgtttca
     3541 aaatggagag ataaatccct ttttcattgt tgaaatgata aaaatatatt tgatttcatg
     3601 taaaaaagag tgcctcatca actaaaaagt ttattttgag acacacacat ttttattaag
     3661 gtaaataaaa atatcacatt tgattaaatt ttaagttaat gaatatatgt gtaaatattt
     3721 aattataagt tattataatt ttacatagta taaaacaatc taatttgtat tatataagat
     3781 aatctaattt tagactaaaa taatctaata taaagaaata gagaaaattc attctcagta
     3841 taagagatat ccaattttcc attgtactta ttaacaattt ctctaatatt ctcaatacca
     3901 tatccgtgag aattactatc ttttttatct gaaataaata gttcttgttt tctattgata
     3961 ggatttacct tgttgtttgt caataaatag ctaaaatact ccttctcaca acgtgccttt
     4021 aataccactt ttctatttga caaatcagga attttcaaag atgcttctat agcgttatct
     4081 aaagaatttg aaaaaatagt acataaatct ataggttcta tacccaagtg attgtctata
     4141 tctatattaa agtgcacatc aacaccattt tcttccaaac ttgtatgacg aagatttaaa
     4201 attgagttaa gagcttggtt tttgcaaaat tgtttgccac taagagtacc tatacctatt
     4261 tttaactgat taaaatactt tttagctcca gcaatatctt caatttctaa atacgattca
     4321 atcatttgaa agtgattatt catatcatgt cgcattttgc gtatttgaat ttgttgattt
     4381 tctagtaagt tatagtattt ttcttttagg tgatttgctt gtttttctat cttcatcttt
     4441 acattttcaa tcaatggctg taaaagaagt atcacaccga tatttgccag aattgctgac
     4501 aagatgatta gataagtgcc ataaggtaag ttgcctaaga taatattctt attactaccc
     4561 atagggatta aattagtagg tggcagaata atagcaatta atattgataa aaatgaagat
     4621 atacatacca tatcaataaa aatccatatt ttatttgata agtattgttt tatattgacc
     4681 aatctattct ttaggaaaat atgtattaaa aaccaaaata ataatttaat tagagcagaa
     4741 attatctgga ctattgaaag tattaaaata tattcttttg agtgtataag ttcctcatat
     4801 atagggttgt ttataaaaag aaaattaagc ccaattataa taggataaag tatcatgaca
     4861 actgatatta taggaattaa tttgcttttg ctacatatta taagtagtat aaaatatccg
     4921 aatagtgtaa acaaaatatt tacggggtcg gaaagccata ttatcatttg actaataata
     4981 gagtagccca aaatcaatat gattttgaaa atccaatgat tcctaaagtc tataaaatag
     5041 gaagtcaact tataaagaaa aaaggctatg aaaatattga ttaatattag aataaaattt
     5101 atgcttgtag agattaaaga ataagtgtcc atttaatata cctttctatt aattaagatt
     5161 ctggaaacta agttttaaaa aattaaatct taaaaattaa aattctggaa attagatttc
     5221 aaagaattga ttttgaaaaa taaaattcta gaaattaagc ttcaaaaaat tgagttttga
     5281 aagattgaaa ttttaaaaat taagtttcaa aaaattaaat ttgaaacaaa actctaaaaa
     5341 ctaagcttca aaaaattaaa ttttgaaaga ttgaaattct agaaactaag ctttaaaaaa
     5401 ttaagtttca aaaaaactct aaaaactaag cttcaaaaaa ttaaattttg aaagattgaa
     5461 attctagaaa ttaagcttca aaaaattaaa tttgaaaaaa caaaactcta aaaactgagc
     5521 tttaaaaaat taagtttcaa aaataaaatt ctagagattg aacttcaaaa attaaggttc
     5581 taacatatac cttgtaaatt ttcctacaac ctcttgatat tttttacggc ttataggaat
     5641 tttttcattc tgaactttgg cataagtttg agttatacta tctacatggt ttagattgac
     5701 aatatacctt tgatgcgtac gtataaaatt agagggaaga acagtttcca tatcatttaa
     5761 ttttccgtag tattctaatg ttttatcaaa ggtaactaca gttaattttc ttagctcgct
     5821 tttaaagtag aggatatctt ttgtattaat tttacaaaga ttagttccaa tatgaactgt
     5881 aataaagttt tctttccatt gttctaattt ttttagtgct tcttttaata ctttacatat
     5941 tttttcagtt ttataaggtt ttaagatgta gttcaaagct cctacatcat acccatgaaa
     6001 tacatagtca gaaaaacctg tgacaaagat gattatagta tcttttgaat gttttcgtat
     6061 agtttttgct atgtcaacgc cattactttt ttcaagttca atatctaaaa aaataatatc
     6121 tatgtaataa ttttcgtgtt ctagattgta tactagactt tctccatttg aatattcttt
     6181 tatttggtag gggtagcccc acaaatccat ttctcttgta atgattttat tcagcatgtt
     6241 tctttgttgt ttttcatcat cacaaataca aatcgaagtc aattttttat ctcctttcaa
     6301 gttttatatt tatatagtta agtatataat atattttgct acctagatat ataaaatgaa
     6361 ataacaatta tatccagata gcaaaataaa attttttata ttagtatact tacacttaaa
     6421 actattctat taaacttatt ctgaagtgct aatgattttc ttattaaaaa atctaataac
     6481 ctttcttatt ataaaatacc aatgctttta ttattataaa aatgtaatga cttttcatat
     6541 tataaaaagc aaatgattat cttactataa aaatacaatg acttttaata ctataaaaag
     6601 c
//
LOCUS       DAMJYN010000142         6577 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.148, whole genome shotgun sequence.
ACCESSION   DAMJYN010000142 DAMJYN010000000
VERSION     DAMJYN010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6577)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6577)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6577
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.148"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(<1..656)
                     /locus_tag="PC466_003462"
     CDS             complement(<1..656)
                     /locus_tag="PC466_003462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016440163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HDF2770813.1"
                     /translation="MKKDTSHIIKRAEHFQVILIGEGLMVGAVAGLIVLLYRILLGQA
                     GTWLSQILKFVEGSTIKIIAWFAVLAVLAWIVSKLVDWEPMISGSGIPQLEGEMTGKI
                     KQVWWRVLPTKFIGGFLSLMGGLALGREGPSIQLGAMAGKGISRALDRGKTEEKFLLT
                     CGASAGLSAAFHAPLAGVMFSLEEVHKNFSVSVLISVMTASLTADYISANFLGMESVF
                     "
     gene            complement(843..1352)
                     /locus_tag="PC466_003463"
     CDS             complement(843..1352)
                     /locus_tag="PC466_003463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrpB family protein"
                     /protein_id="HDF2770814.1"
                     /translation="MIGLKCGMVKLLEHQMIWDKSAKDVIILLKSIWDKTAIDIQHIG
                     STSIPSISAKPIIDIVVGVASLEEAKLYLERLEQCGIVFRGQDVPKQLLFAMGDFEKN
                     TRTHHIHVVEWNSVAWNNYINFRDYLNTFTDKAKLYDSHKQKLALQFEDNRKIYTQRK
                     QELINILLE"
     gene            complement(1427..1840)
                     /locus_tag="PC466_003464"
     CDS             complement(1427..1840)
                     /locus_tag="PC466_003464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003507530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HDF2770815.1"
                     /translation="MKMPKESIDTIMFAPCGMNCMVCYKHCYHKKPCAGCLNSDTGKP
                     EHCRKCKIKDCVCQKGLFYCFECFNFPCKLIKNLEKSYNKRYQASLMENSKFVQQYGL
                     EKFMQKQKERYTCSKCGGIISIHDRECSECQEKVK"
     gene            2277..2936
                     /locus_tag="PC466_003465"
     CDS             2277..2936
                     /locus_tag="PC466_003465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid stabilization protein"
                     /protein_id="HDF2770816.1"
                     /translation="MDEKILELLQEIQGNISNMQGSISGIEGTVNGMQGNINYMQGNI
                     NYMQGTISDMQGTISDMQGSINGIEGTISDMQGSINGIEGTISDMQSNINDIEGTISD
                     MQGSISSMDGTINSMQDSITDMQGEIKEVNSRLDNMEPDIKDLKTGQVETSSRLDTIQ
                     SDVTEIKSDVKINRNTLDTVIKHTSSLVEDTSDIKNDLNNIEIVTSKNWNDIAKLKSV
                     K"
     gene            complement(3543..3722)
                     /locus_tag="PC466_003466"
     CDS             complement(3543..3722)
                     /locus_tag="PC466_003466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDF2770817.1"
                     /translation="MLQTGKQGADKKYLDNMFFVKGYVEELLFLDNSYDIVFSCIVFH
                     HCTNVQNIFCIFWKW"
     gene            complement(3947..4480)
                     /locus_tag="PC466_003467"
     CDS             complement(3947..4480)
                     /locus_tag="PC466_003467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HDF2770818.1"
                     /translation="MQYISYYHSPIGNILLASDNVGLTGLWFENQKYYAYNLDQEHQE
                     KELPIFEQTKKWLDIYFSGEEPNFTPSLHMVGTPFQTTVWKILQQIPYGKTITYGEIA
                     HKVAQQKGISKMSAQAIGGAVGHNGISIIVPCHRVVGTNGSLTGYAGGIDRKIKLLSL
                     EKVSVQHYFIPKKGSAL"
     gene            complement(5298..5870)
                     /locus_tag="PC466_003468"
     CDS             complement(5298..5870)
                     /locus_tag="PC466_003468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HDF2770819.1"
                     /translation="MWIYQKTLEHPVNIRQADPRMAKYIMTQLGGPNGELAAATRYLQ
                     QRYTMPTGKSRALLTDIGTEEMAHVEIISSVLYQLIGSCTPEELKAAGLGSNYANFGH
                     GLQPVDSNGVNFTTSYINVFGDSVTDLHEDMAAEQKALATYYQLINLTDDPDLKDILR
                     FLGEREVVHYQRFGEALMDVYEFTECKHQF"
     gene            complement(5932..6195)
                     /locus_tag="PC466_003469"
     CDS             complement(5932..6195)
                     /locus_tag="PC466_003469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat protein CotJB"
                     /protein_id="HDF2770820.1"
                     /translation="MSLNRRELLERISEYQFACIELNLYLDNNPRDKKALDLYNRYCD
                     KFTQAVCDYESKYGALTNFGYESSEYPWSWISEPWPWDKSFYK"
     gene            complement(6195..6416)
                     /locus_tag="PC466_003470"
     CDS             complement(6195..6416)
                     /locus_tag="PC466_003470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat associated protein CotJA"
                     /protein_id="HDF2770821.1"
                     /translation="MGYLKEDKQDYCCEFARPYINRQIYDDTYNPKTALKRGTLFPEL
                     DLIESNNYNDWLYSNPKNRVRAKKGGNMY"
BASE COUNT         2302 a         1132 c          812 g         2331 t
ORIGIN      
        1 tggaatacag actccattcc taggaaattg gctgaaatat agtctgctgt caaagatgct
       61 gtcatcacag aaattaaaac agatactgaa aagtttttat ggacttcttc aagtgaaaac
      121 ataacacctg ccagtggtgc atgaaaggct gctgataatc cagcacttgc cccacaggtt
      181 aacaggaatt tttcctctgt cttccctcgg tcaagagctc tagaaatacc tttacctgcc
      241 atagcaccaa gctgaatgga aggaccttcc cttcccaaag caagaccacc cataagtgat
      301 aagaatcctc caataaattt tgtgggcaac actcgccacc atacttgttt tattttccct
      361 gtcatttccc cctcaagctg agggatacca cttccagaaa tcattggctc ccagtccacc
      421 aactttgata caatccacgc aagtactgca agtactgcaa accaagctat tatttttatt
      481 gtagaacctt ctacaaattt taaaatttgg ctaagccaag taccagcctg ccctaaaagt
      541 atcctgtata aaagcacaat caaaccagcc acagccccaa ccataagtcc ttcaccaatc
      601 aaaattacct gaaagtgctc tgcccgtttg ataatatgag atgtatcctt tttcatactg
      661 ttcctccttc atccaataat tctacacaat ctgaacctcc aatgactaaa gtcatgagtg
      721 tgtacagata ttttttaatc aacaaaaata gatttttatt tactaaatat aagaaaataa
      781 ttgttcaatt tctcaataaa tgtaaattta ttcttttagg tatttattct ccacagtcgt
      841 gcttattcca gcaaaatatt tattagttct tgctttctct gtgtatagat tttacgattg
      901 tcctcaaact gtaatgctaa tttttgttta tgactatcat agagttttgc tttgtctgta
      961 aaagtattta gataatctcg aaaattgata taattattcc atgcgacact attccattca
     1021 acaacatgaa tatggtgagt acgagtattt ttctcaaaat ctcccatagc aaaaagtaat
     1081 tgttttggta catcctgacc tcgaaaaacg attccacatt gctctaacct ttcgaggtat
     1141 aatttagctt cctctaaaga agcaacacct acaacaatat caataatagg ctttgcgcta
     1201 atactgggaa tagaagtgct tccaatgtgt tgaatatcaa tggcagtctt atcccatata
     1261 cttttcaata atataatgac atcttttgca cttttatccc atatcatctg atgttccaat
     1321 aatttaacca taccacattt taaacctatc actatatacc acctcaatat aatccacctt
     1381 tatatatata ttacaatttt ttctatcttg ataaacagtg atctagctat ttcacttttt
     1441 cttgacactc gctacattcc ctatcatgaa tagatataat tcctccacat ttagaacaag
     1501 tatatctctc cttctgcttt tgcataaact tctctaaacc gtactgctga acaaatttac
     1561 tattttccat aaggcttgct tgatatctct tgttataact tttttcaaga ttttttatga
     1621 gtttacaagg aaaattgaaa cattcaaaac aataaaacaa ccctttttga cagacacaat
     1681 cctttatttt acacttacgg cagtgttctg gctttcctgt atcgctgttc aaacaaccag
     1741 cacatggctt tttgtgataa caatgcttat agcaaaccat acaattcatt ccacaaggag
     1801 caaacataat cgtatcaata ctctcttttg gcattttcat aacattttac tcctttcaaa
     1861 aatccaattt gtcgaattgt tatatattca tattgtaaca taaaaaatag ctaaaaaatt
     1921 catgcacttt cattgccaat aaattttcaa ggaaatatga aagtttaaaa ctaagaataa
     1981 aaagaaataa aaaggaagct actaatcaaa atattcaaac acaagtaatc aattatgata
     2041 ttaccagcag ttttaaatac aaatataacc acatatgcct caaaaacact tattatagta
     2101 tcttagacac ttagacaata cacaagattc attaataaaa aagttctcaa tatagatata
     2161 tttaaccatg ttttgaatag cagataatta tatgattaaa aattaaatat gacatagcgt
     2221 ttgtggaata taacacctaa attatgttat aataataaaa caggagtgtg atagtgatgg
     2281 atgaaaaaat attagaatta ttacaggaaa tacaaggtaa tattagtaat atgcaaggta
     2341 gtatcagtgg tatcgaaggt actgttaatg gcatgcaggg taatattaac tatatgcagg
     2401 gtaatattaa ctatatgcaa ggtactatta gcgatatgca aggtactatt agcgatatgc
     2461 aaggcagtat caatggtatc gaaggcacta ttagcgatat gcaaggcagt atcaatggta
     2521 tcgaaggcac tattagcgat atgcaaagca atatcaatga tatcgaaggt actattagcg
     2581 atatgcaagg cagtatcagt agtatggatg gcactattaa tagtatgcaa gacagtatta
     2641 ctgatatgca aggtgaaatt aaagaagtca atagtagatt agacaatatg gaacctgata
     2701 ttaaagactt aaaaactgga caagttgaaa ctagtagtag acttgataca attcagagtg
     2761 atgttacaga aattaagtca gatgtaaaaa ttaacagaaa tacattagat acagtgatta
     2821 aacatacctc ttcattagta gaagatacat cagatattaa aaatgattta aacaatatag
     2881 agatagtcac atctaagaat tggaatgata ttgctaaatt aaaatcagtt aaataatata
     2941 ccatagtaaa aaatacctga aaatttcaca tacttcttta aagttatacc aaattttata
     3001 cagaaatact gattatccga caacacactt tacttataaa taatttatta aaaaatactc
     3061 attttatcct aaaattaaca cgactaaatg agtcttgata taataataaa aaataaggga
     3121 gattgaacac taaaaagttg tgtatctccc ttatattcta taatatagtt atataatttt
     3181 tcagcctaaa ataaaagtcc atctttgatt aaaacatatc cccttatcac ttataaaagg
     3241 ataaaatctt gttttcattt ttccatttat atcttcttgc ttaagagtaa taattttttc
     3301 ttttgatact ttaagtgttt ggttaaattt aaccaatcga ctaagttttg ttcaacatct
     3361 atttttcata ttttccaata cttaatctat tttttataaa taattctttt atttctaact
     3421 cacttacatt ttttacataa aacgaagcat ataaatttca accttatctt gtatggttct
     3481 taatacttaa tgagtagctt aagtatcaat cattataaat tttcccctta tatttaacac
     3541 tcttaccatt tccaaaatat acaaaatata ttttgaacat ttgtacaatg atgaaataca
     3601 atacatgaaa atacaatatc ataactgtta tctaaaaata gaagttcttc aacataacct
     3661 ttcacaaaga acatattatc taagtatttt ttgtctgctc cttgttttcc tgtttgtagc
     3721 atataaatta ctgcatctaa acatataact actcacacga aaaaagaaaa taaacttcca
     3781 aaatacaagc tctaaaacta cctctaaagt tatataatgt ttactaggaa taaggttgta
     3841 taacatatag tttaaagaat agttttttaa aattgcaagt tattgctttc aaaattagat
     3901 gtttatatat caaataaatg attaagaatt tctaaattta atggctttat aatgcactcc
     3961 ctttctttgg gataaaataa tgttgcacag atactttttc taaagataac aattttattt
     4021 ttctatcaat tccaccagca taccctgtca aactcccatt tgttcctaca acacgatgac
     4081 atggaacaat aatagagatt ccattatgcc ctactgcacc accgattgct tgtgctgaca
     4141 ttttagatat tcctttttgt tgagcaactt tatgtgcaat ttctccataa gtgattgttt
     4201 taccatatgg tatttgttgt aaaattttcc acactgtagt ctggaaagga gtacctacca
     4261 tatggagtga tggtgtaaaa ttgggctctt ctcccgaaaa ataaatatct agccatttct
     4321 ttgtctgctc gaaaattggc aattcttttt cttgatgttc ttggtcaaga ttataagcat
     4381 aatacttttg attctcaaac caaagaccag ttaacccaac attatctgat gctaaaagaa
     4441 tatttccaat tggactatgg taatagctaa tatattgcat acaattcctc cttatattct
     4501 gaaaacttca ctcaaatcat tagacacttc ttttctatct gccattatgt aaaaacatac
     4561 taatataatt tccttctgac tacactttcg ttataatatc tatcctcata tcatattagt
     4621 tttatattta cctgaatctg ttcatccttt ttttcctttc cctttgatgg atataaaatt
     4681 catacattta agcttcctac tgtattaact tttatagaag tgtatattat aattttatca
     4741 ctaaatagac aaaaaaatat cgatataaca tcaagaaata ttttactgag tttcgcttat
     4801 taaaagcaac tgaatttcta aagggtacag atgagctaat aagtgatatt gatataaaag
     4861 ttgtttttca ttaagtaatc tattttagta aatgttttaa agaaaaaacg ggatattctc
     4921 caaaagtgta cagaaatata aaaaaagaga tatgattttt tatttctttt gattatccaa
     4981 agagtaaata aaaaatattg taaaaaactt actaacaacg gcaatgcttt gaactatggt
     5041 aatactttga acttttgatt ggactttttt tgctaaaata atatatttaa atagcaaagt
     5101 aatctgttta atcaataaaa aataagagat aaaagaaatc aactaaaacc tttacctctt
     5161 attttgatag tttatcagag ctaatattta cactcttttt atttttgata cttcattaaa
     5221 aatgatgctt attctctttt catttttaat acttcattaa aattgatgct tactctctat
     5281 tcacttttaa tacttaatta gaactgatgc ttacactctg taaactcata aacatccatt
     5341 aatgcttcac caaatctttg atagtgaact acttccctct cacccaaaaa tctcaatata
     5401 tctttcaaat cagggtcatc agttaaattt attaattgat agtacgtagc caatgctttt
     5461 tgttcagcag ccatatcctc atgtaaatca gttaccgaat cgccaaagac attaatataa
     5521 cttgtagtaa agtttactcc attagaatct actggttgaa gaccatgtcc aaaattagca
     5581 taattactac caagtccagc agccttaagc tcttccggag tacaactgcc tattaattga
     5641 tataacactg aagaaattat ctcaacatgg gccatttcct ctgtacctat atcagttaaa
     5701 agtgcgcgag attttccagt tggcatagta tatctttgtt gaagatatct agttgcagct
     5761 gccaactcac cattaggtcc tcccaactga gtcatgatat attttgccat tctagggtct
     5821 gcttgtctta tgttaactgg atgttccagt gttttttgat aaatccacat attatcttac
     5881 tcctccttaa tatatattta ataataattc taattttaaa acttaataat tttatttata
     5941 aaatgatttg tcccatggcc aaggttcaga tatccatgac caaggatatt cacttgattc
     6001 atatccaaaa ttagttaatg ctccatattt agattcataa tcacacacag cttgtgtaaa
     6061 tttatcgcag tatctattgt ataaatcaag agctttctta tcccttggat tgttatctaa
     6121 atataaattt aattctatac aggcaaattg atattctgaa attctctcta aaagttctct
     6181 tctatttaat gacattagta catgttaccc ccttttttag ctctaactct atttttagga
     6241 tttgaatata gccaatcatt atagttattt gactctatta aatctaattc aggaaataaa
     6301 gtacctcttt ttaatgctgt ttttggattg tatgtgtcat cataaatttg acgattgatg
     6361 tatggtctag caaattcaca acaatagtct tgtttatcct cttttaaata tcccattaat
     6421 tatcctcctt aatttttaga attttaaaat agcattattt ttaaaaattg tatacttgtt
     6481 ctatattata gtcagtagtt ttaataggtc tttaataaga ttaaataatt aaataagtat
     6541 ctttttttgt tcttatttta cctataaaaa ttttcct
//
LOCUS       DAMJYN010000143         6391 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.149, whole genome shotgun sequence.
ACCESSION   DAMJYN010000143 DAMJYN010000000
VERSION     DAMJYN010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6391)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6391)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6391
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.149"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            295..1239
                     /locus_tag="PC466_003471"
     CDS             295..1239
                     /locus_tag="PC466_003471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase regulatory
                     subunit"
                     /protein_id="HDF2770822.1"
                     /translation="MKFLRIEDEVIYSKKRYKLKREIDKLFLDEEYFQIEPQLFEEYD
                     EFTTINNKIPEESMVKVVNGKVMVLRADITTSIIKSLVPRWEDGLKLKLFYNSSIYKN
                     KNTVGIKEIRQIGCEYLGEASVEADREVVKLALKILEKYNNNFILEVGSSKYIHGLLE
                     ELNLNKNCENQIKNLLYTKNTHELKVYIEELKIKREVKELLSNILSLQGNLYNVIEKS
                     NKFYCNNKMKQALEELKQVNNLIEECNFLDKARFDLSMITMLDYYEGIMFRGYYPNSY
                     KEILSGGRYDSLTKEYGKEIPAIGFTLSVDELMKYVYK"
     gene            1261..1887
                     /locus_tag="PC466_003472"
     CDS             1261..1887
                     /locus_tag="PC466_003472"
                     /EC_number="2.4.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase"
                     /protein_id="HDF2770823.1"
                     /translation="MDYLTIALAKGRIEGESFKKFKKMGLGDSIDTDTRKLIFKDEEN
                     KIIYIHVKPSDVVTYVEKGVADLGIAGKDTILENETDVYEIYDLGFGKCKFAVAGLKG
                     DSIYREDEYLKVATKYPNIAKKYFKEKGQKIEIIKLNGSVELAPIVGLSDVIVDIVET
                     GNTLKANGLEILEDICNISARIISNRASYRFKYEQIQNIIRLFEELDN"
     gene            1921..2970
                     /gene="hisC"
                     /locus_tag="PC466_003473"
     CDS             1921..2970
                     /gene="hisC"
                     /locus_tag="PC466_003473"
                     /EC_number="2.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate transaminase"
                     /protein_id="HDF2770824.1"
                     /translation="MREKESIRELRGYEPNHVNCKVKLDANEGSKRLFKYLIKEISDS
                     DIDLNLYPEDSYSDLKESIIDYINISGVNKKNLLVGNGSSEIIDLIIHTFVDKDEVIL
                     SFSPSFSMYSIYSQINGSKFIGVESDENLVINIDNVIEKVKENNPKIVIVCNPNNPTG
                     TILKREEIIKLLDSTNSLVVLDEAYMDFGEESMLSDVFKYDNLIVLRTLSKAFGLAGI
                     RTGYMLSNSSLINSVEKVRPPYNLNSLSDFIATRALRNKDVVKAYIKEVKEEREVLYE
                     EMIGMGIKAYKSQANFILFYSEIENLSQKLIDRGVLIRKFGGKLENYYRVTIGDKEEN
                     SMFVGAIRDILKKEK"
     gene            2973..3551
                     /gene="hisB"
                     /locus_tag="PC466_003474"
     CDS             2973..3551
                     /gene="hisB"
                     /locus_tag="PC466_003474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazoleglycerol-phosphate dehydratase HisB"
                     /protein_id="HDF2770825.1"
                     /translation="MRIWKVERNTFETQILVELNIDGSGKAEIDTGIGFLDHMLTLMS
                     FHGKFDLKVICKGDTYVDDHHSVEDIGIAIGEAFKNALGDKKGIRRYSNIYIPMDESL
                     SMVAIDISNRPYLVFNAKFDTQMIGSMSTQCFKEFFRAFVNESRVTLHINLLYGENDH
                     HKIESIFKAFARALKEGSEIVSNEIASSKGVL"
     gene            3553..4158
                     /gene="hisH"
                     /locus_tag="PC466_003475"
     CDS             3553..4158
                     /gene="hisH"
                     /locus_tag="PC466_003475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisH"
                     /protein_id="HDF2770826.1"
                     /translation="MNIIVDYGLGNIDSVSRGFRKAGIETKISSDIDEIKQADSLILP
                     GVGAFRDSISALDKLGLIPIIKEHVSKGKFMIGICLGMQLLYEKSYEYGEYEGLGLIK
                     GSIDKLDITLKVPHMGWNNLKFNKANDDILKYINEDDYVYFVHSYYANSSNEELVAFS
                     EYEKKIPAIVRKGNVYGIQFHPEKSGEVGLNILRAYGEMIK"
     gene            4155..4877
                     /gene="hisA"
                     /locus_tag="PC466_003476"
     CDS             4155..4877
                     /gene="hisA"
                     /locus_tag="PC466_003476"
                     /EC_number="5.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-(5-phosphoribosyl)-5-[(5-
                     phosphoribosylamino)methylideneamino]imidazole-4-
                     carboxamide isomerase"
                     /protein_id="HDF2770827.1"
                     /translation="MIIFPAIDIKDNKCVRLTQGEFDKVNVYYDNPLEVAYKWKNEGA
                     EYIHIVDLNGARSEFGINTKIIEDIANNIDIPIQVGGGVRDKGKVKSLINAGVTRVIL
                     GSIAIENLNLVEELVNEYKEKIVVSIDAKDGKVAVRGWEVVSDVDSLTLCKQLEKIGV
                     QTIVYTDISKDGMLQGPNFDIYERIAKETSLNVIASGGVTSIEDVKRLKAMNLYGAII
                     GKALYDKKIDFKEAQQLCLLGE"
     gene            4859..5617
                     /gene="hisF"
                     /locus_tag="PC466_003477"
     CDS             4859..5617
                     /gene="hisF"
                     /locus_tag="PC466_003477"
                     /EC_number="4.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000880088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisF"
                     /protein_id="HDF2770828.1"
                     /translation="MLTRRIIPCLDVRNGRVVKGKKFKDIVDVDSPEVLGKFYSDCGA
                     DELVFYDITASNEERKTSLEFVTKVAENINIPFCVGGGVNKLEDFTDILRKGADKVSI
                     NSSAVKNPELIREASLKFGAQCVVLSIDAKKNEEGSWSVYVKGGREKTNLDAIEWAVK
                     GVELGAGEIVVNSMDEDGMKNGYDIELLSKITSLVNVPVIASGGAGKKEDFYEAVNKS
                     NVDGILAASVFHFGEIKINDLKKYLKNMGVEVRL"
     gene            5645..6313
                     /locus_tag="PC466_003478"
     CDS             5645..6313
                     /locus_tag="PC466_003478"
                     /EC_number="3.5.4.19"
                     /EC_number="3.6.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphoribosyl-AMP
                     cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE"
                     /protein_id="HDF2770829.1"
                     /translation="MDNKCNNVYSDEVEEFIRSIKFDDKGLVPVVVQEVVSKDVLMLA
                     YMNKDAIKKTLKDKVACYFSRSRQKLWVKGETSGNTQKVVKMSYDCDVDTILLFVEQT
                     GVACHTGNYSCFYRDLFDDSSKMEPEVQTNILKELYDLINERKNNPVEGSYTNYLFEK
                     GIDKILKKVGEESSEVIIASKNTDKSELIYEISDLVYHTLVLMIEKGVEIDEIKKELL
                     KRRK"
BASE COUNT         2605 a          540 c         1264 g         1982 t
ORIGIN      
        1 ctgtaaattt agaatattaa taaaaattat ttgggaggaa attatcatgg tgagattaaa
       61 tatagtaaaa ttaaatacaa aattaaatca tcaccatcat catagattaa agggattgta
      121 atatgaaatt aattcataga cacaagccct gtttttagtg taattggtct tgtatctatg
      181 atgggaagta attttaggag aaaattatag ccatataggt ataaagccta tatggctttt
      241 ttattgtttt aaatttgcaa atataagagt aaatttaatg aagagggtga gaatgtgaaa
      301 tttttgagga ttgaagatga agttatttat tctaaaaaaa gatataaatt aaaaagggaa
      361 atagataaac tttttttgga tgaagaatat tttcaaatag aaccacaatt atttgaagaa
      421 tatgatgaat ttacaactat aaataataaa attccagaag aatctatggt aaaggttgta
      481 aatggaaaag taatggtact tagagctgat ataactacaa gtataataaa aagccttgta
      541 ccaagatggg aagatggttt aaagcttaag cttttttata attcatcaat atataaaaat
      601 aaaaatacag ttggaataaa agagataaga caaataggtt gcgagtatct aggagaagcc
      661 tctgtagaag cagatagaga agtagtgaaa ttagctctta agatacttga aaaatacaat
      721 aataatttta ttttagaggt tgggagtagc aagtatattc atggtttgtt agaagaatta
      781 aatttaaata agaattgtga aaatcaaatt aaaaatttac tatatacgaa gaacactcat
      841 gaattaaaag tatatattga agaactgaaa attaagcgtg aagtaaaaga gctattatca
      901 aatattttaa gcttgcaagg gaatttatac aacgttattg aaaaatcaaa caagttctat
      961 tgtaataata agatgaagca agctcttgaa gaattaaagc aagtaaataa tttaattgag
     1021 gaatgtaatt ttttagataa ggctagattt gatttatcaa tgattactat gcttgactat
     1081 tatgaaggaa ttatgtttag aggatactac ccaaactcat ataaagaaat tcttagtggt
     1141 ggaagatatg attctttaac taaagagtat ggaaaagaaa ttccagccat tggatttaca
     1201 ctaagtgttg atgagttaat gaagtatgta tataagtaaa gtttagaagg agggattgct
     1261 ttggattatt tgactatagc actagcaaaa ggacgaattg aaggggaatc atttaaaaaa
     1321 tttaaaaaaa tgggtctagg agatagtata gacacagata cgagaaaact aatttttaaa
     1381 gatgaagaaa ataaaattat atatatacat gtaaagccat cagatgtagt tacatatgtt
     1441 gaaaaaggag tcgctgacct tggtatagca ggtaaagata ctattttaga gaatgagaca
     1501 gatgtatatg aaatatatga tttaggtttt ggaaaatgta aatttgctgt agcaggatta
     1561 aagggagata gcatatatag agaagatgaa tatctaaaag tggcaacaaa gtatcccaat
     1621 atagcaaaaa agtattttaa agagaaaggt caaaaaattg aaataataaa attaaatggt
     1681 tctgtagaac tagctccaat agtagggttg tcagatgtaa ttgtagatat agttgagact
     1741 ggcaatacac ttaaagcaaa tggtcttgaa atattagaag acatatgtaa tataagtgct
     1801 agaattatat caaatagagc tagctataga tttaaatatg aacaaattca gaatataatt
     1861 cgtttatttg aagaacttga taattaaaat ataattgaac tttataagga gggatttaag
     1921 ttgagagaaa aagaaagtat aagagagtta aggggatatg aaccaaatca cgtaaactgt
     1981 aaagtaaaac ttgatgcaaa tgaaggaagt aagaggttgt ttaaatacct tattaaagaa
     2041 atttcagata gtgatataga tttaaattta tatcctgaag attcttatag tgatttgaaa
     2101 gaatctataa tagattacat aaatatttct ggagtaaata agaaaaatct tctagtagga
     2161 aacggttcaa gtgaaataat tgatttaata atacatactt ttgtagataa agatgaagta
     2221 atattgagtt tctctccaag ttttagtatg tattctatat atagtcagat aaatgggtct
     2281 aaatttatag gtgttgaaag tgatgaaaat ttagttataa atatagataa tgtgattgaa
     2341 aaagtaaagg agaataatcc taaaatagta attgtatgta atcctaataa tccaactgga
     2401 acaatattaa agagggaaga gataataaag cttttagatt caactaatag tctagtggtt
     2461 ttagatgaag catatatgga ttttggagaa gaaagcatgt taagtgatgt ttttaagtat
     2521 gataatctaa tagttcttag aactttatca aaggcatttg gattggctgg aataagaaca
     2581 ggatatatgt tatctaatag tagtttaata aattctgttg agaaagtaag acctccatat
     2641 aatttaaatt cattatcaga ctttattgct acaagagcac ttagaaataa agatgtggta
     2701 aaggcttata taaaggaagt aaaagaggaa agagaagttt tatatgaaga aatgattggt
     2761 atgggaatta aagcatacaa atcacaagca aattttatat tattttattc tgaaatcgaa
     2821 aatttatcac aaaaacttat tgatagagga gttttaataa gaaaatttgg tggaaagtta
     2881 gaaaattatt acagagttac aattggtgat aaagaagaaa attctatgtt tgttggagct
     2941 ataagagata ttttgaaaaa ggagaaatag gtatgagaat ttggaaggta gaaagaaata
     3001 cttttgaaac acagatttta gtagaattaa atattgatgg ttctggtaaa gctgaaatag
     3061 atactggaat aggattttta gaccatatgc ttaccttaat gtcatttcat ggcaagttcg
     3121 atttaaaagt gatttgtaag ggtgatacat atgtagatga ccaccatagt gtagaagata
     3181 taggtatagc tataggtgaa gcatttaaaa atgcactagg tgacaaaaaa ggaatacgaa
     3241 gatattctaa tatctatata cctatggatg aatctctatc aatggtagca atagatataa
     3301 gtaatagacc ttatcttgta tttaatgcta aatttgatac ccaaatgatt ggtagtatga
     3361 gtactcaatg ctttaaagaa ttttttagag cttttgtaaa tgaatcgaga gtaacattac
     3421 atatcaatct cttatatggg gaaaatgacc atcataagat agaaagtatt tttaaagcat
     3481 ttgcaagagc tttaaaagag ggtagtgaaa tagtttctaa tgagatagca tcttcaaagg
     3541 gggttttgta gaatgaatat aatagtagac tatggtcttg gaaatataga ttctgtgtct
     3601 aggggtttta gaaaagctgg aatagaaact aaaatttcta gtgatataga tgaaataaaa
     3661 caggcagatt cacttatact tccaggtgtt ggagctttta gagattctat aagtgcctta
     3721 gataaactag gattgatacc aataataaag gagcatgttt ctaagggtaa atttatgata
     3781 ggtatatgtc taggaatgca attactttat gaaaaaagtt atgagtatgg agaatatgaa
     3841 ggattaggac ttataaaagg aagtattgat aaactggata taactttaaa agtgccacat
     3901 atgggatgga ataatctaaa atttaataag gcaaatgatg atatacttaa atatataaac
     3961 gaagatgatt atgtatactt cgttcactca tattatgcaa attcatcaaa tgaagaacta
     4021 gttgcatttt cagaatatga aaagaaaatc cctgctattg ttagaaaagg caatgtatat
     4081 ggtatacaat ttcatcctga aaaaagtgga gaagtagggt taaatatatt aagagcatat
     4141 ggggagatga taaaatgata atatttccag caatagatat aaaagataat aagtgtgtaa
     4201 gactcacaca aggagaattt gacaaagtaa atgtatatta tgataatcca ttagaagtag
     4261 catataaatg gaaaaatgaa ggagcagaat atatacatat agtagattta aatggtgcta
     4321 gaagtgaatt tggtataaat acaaaaataa ttgaggatat agcaaacaat atagatatac
     4381 ctattcaagt tggtggtgga gttagagata agggaaaagt caaaagttta ataaatgctg
     4441 gtgttactag agtaatatta ggtagtatag cgattgaaaa tttgaatttg gttgaagaat
     4501 tggtcaatga atataaagag aaaattgtag tttctataga cgctaaagat ggaaaagtag
     4561 cagttagggg atgggaagtt gtaagcgatg tagactcatt aacattatgt aaacaacttg
     4621 aaaagatagg tgtacaaact attgtttata cagatatatc aaaagatggg atgttgcaag
     4681 ggccaaattt tgacatatat gaaagaatag caaaggaaac gtcattaaat gttattgctt
     4741 ctggaggcgt aacttctata gaagacgtaa aaagactaaa agctatgaac ttatatggtg
     4801 caataatagg taaagcgctt tatgataaaa agatagactt taaggaggca caacaattat
     4861 gcttactagg agaataatac cttgtctaga tgtgagaaat ggaagagttg taaagggaaa
     4921 aaaatttaaa gatatagtag atgttgatag tccagaagta cttggaaaat tttatagtga
     4981 ttgtggtgca gatgaacttg tattctatga tataactgca tcaaatgaag agagaaagac
     5041 atctttagaa tttgtgacaa aagttgcaga aaatataaat ataccatttt gtgttggtgg
     5101 aggagtaaat aaattagaag atttcactga tattttaaga aaaggtgctg ataaggtttc
     5161 tataaattca tcagcagtca aaaatcctga attaataagg gaagcttcat taaaatttgg
     5221 agcacaatgt gttgttttat cgatagatgc aaagaaaaat gaagagggtt catggagcgt
     5281 atacgtaaaa ggtggaagag aaaaaactaa tctggatgca attgaatggg ctgttaaagg
     5341 tgtagaactt ggagcaggag aaattgttgt aaatagtatg gacgaagatg gaatgaaaaa
     5401 tggatatgat atagaattat tatcaaagat aacttcttta gtaaatgtac ctgtcatagc
     5461 atctggaggc gctggaaaaa aggaagattt ttatgaggca gttaataaat ctaatgtaga
     5521 tggaatttta gcagcatctg tttttcattt tggcgagata aaaataaacg atttaaagaa
     5581 atatttaaaa aacatgggtg tagaagtaag attataagtt aaatactaaa aggagattag
     5641 aaatatggat aataagtgta acaatgtata cagtgatgaa gtagaggaat ttataagaag
     5701 tataaagttt gatgataaag ggttagtccc tgttgttgtt caagaggtag ttagtaaaga
     5761 tgtactgatg ttagcatata tgaataaaga tgctataaag aaaaccttaa aagataaagt
     5821 agcttgctat tttagtagaa gtagacaaaa actttgggtt aaaggtgaga catctggtaa
     5881 tactcaaaaa gtagttaaga tgtcttatga ttgtgatgta gatactatac tactttttgt
     5941 tgaacaaact ggtgtagctt gtcatacagg caattattct tgtttttaca gagacttgtt
     6001 tgatgatagt tcaaaaatgg agcctgaagt acaaacaaat atattgaaag aattatatga
     6061 tttaatcaat gaaagaaaaa ataatccagt tgaaggttct tatactaatt atctttttga
     6121 aaaaggaata gataagattc ttaaaaaagt aggtgaagag agtagtgagg taattatagc
     6181 atcaaaaaat accgataaaa gtgaacttat ttacgaaatt agcgatttag tgtatcatac
     6241 attggtttta atgatagaaa aaggtgttga aattgatgaa ataaaaaaag aattacttaa
     6301 aagaagaaaa tagaatagga tagattaatg gtaataagaa aatataccgc ttttaataaa
     6361 aagtggtata ttttttattt tatattttcg a
//
LOCUS       DAMJYN010000144         6286 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.150, whole genome shotgun sequence.
ACCESSION   DAMJYN010000144 DAMJYN010000000
VERSION     DAMJYN010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6286)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6286)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6286
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.150"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(143..358)
                     /locus_tag="PC466_003479"
     CDS             complement(143..358)
                     /locus_tag="PC466_003479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770830.1"
                     /translation="MHINQTGFISNGLGIKQQQKKEPTSNSFSYNAPSSWKPVGRDSV
                     QYNCGFELIATLVREGSSWAFNFIVQP"
     gene            complement(541..885)
                     /locus_tag="PC466_003480"
     CDS             complement(541..885)
                     /locus_tag="PC466_003480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770831.1"
                     /translation="MNYRLKKSVTTILSLLIMTILLPTNASASKVEDSSMKVMYSEKQ
                     VTDMDKLYDMAKNGITDVKSSNEKGIIKNARTGESIYVDSISTTQLLEVKQSKNLTSK
                     IYSKTVFLILIQ"
     gene            1012..1395
                     /locus_tag="PC466_003481"
     CDS             1012..1395
                     /locus_tag="PC466_003481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770832.1"
                     /translation="MRKKFFIGILIVLIISVIAILNIKNDKNVFIGESENWKAKFVTT
                     EGHSKLEIKYKNSKDVVEQKFNYSYQFIDGEDAVVVVKNEILEAGQEKAIKIQRPGLY
                     SNRESSYKLIISWNGNEETINLKKK"
     gene            complement(2604..2855)
                     /locus_tag="PC466_003482"
     CDS             complement(2604..2855)
                     /locus_tag="PC466_003482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770833.1"
                     /translation="MSSYFITRGDVMKILQQFKPYKYDKEKNIEYDEKIIANQNTEVY
                     IVYPRISDEENRRRWEEFNEVAKEVAINIAMKKVETVES"
     gene            complement(3101..3256)
                     /locus_tag="PC466_003483"
     CDS             complement(3101..3256)
                     /locus_tag="PC466_003483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="regulator"
                     /protein_id="HDF2770834.1"
                     /translation="MALDVKIEVKIIKDVVILNIIHWKKETSLLTVKIARGQGDLSYV
                     KYFTNES"
     repeat_region   4473..5430
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=4473..4501
                     /rpt_unit_seq="ctttacataccacttagttaatataaaac"
BASE COUNT         2245 a          884 c          640 g         2517 t
ORIGIN      
        1 catatattaa gaaatattaa tagtaaataa gcaattgtta ctataacgta ggaattatct
       61 ttaaaaacac aaattaattt acattctcta attttaaagt atatgtatat ctttgatttt
      121 aataaaattc acttaaaata ttttaaggtt gaacaatgaa attgaatgcc caagaacttc
      181 cttctcttac taatgttgca attaattcaa acccacaatt gtattgaact gaatctctac
      241 ctactggttt ccaactagaa ggtgcattat atgagaaaga atttgatgtt ggctctttct
      301 tttgttgctg cttaattcct agcccattag aaataaatcc agtttgattt atatgcaccc
      361 ttctatttgt tacacgaatc tggccgtctg caatagacca gtttccagaa actttactaa
      421 cggaaatata ttgaaatgct ccatctcctt ttgatattgt atatgtaact gtaccagatg
      481 cttttacacc accagtttta tcccatccat cttctgatat acttgctttt ctaagaggct
      541 ttattgtatt agtatcaaaa aaactgtctt agaatatatc tttgatgtta aatttttaga
      601 ttgtttaact tctaataatt gagttgttga tatagaatca acgtatatgg actctcctgt
      661 tcttgcattt ttgattatac ctttttcatt ggaactttta acatcagtaa ttccattttt
      721 agccatatcg tataatttgt ccatgtctgt tacttgtttc tctgaataca ttactttcat
      781 agatgaatct tctaccttac tagcacttgc atttgttggt aatagtattg tcattatgag
      841 taaagataaa atagttgtta cagatttttt taacctataa ttcatattaa tccttacttt
      901 ttatttgtta taacagacat tctattgtaa tagaatataa atccacaata tttttaaaat
      961 tagtattgaa taactattct catgttataa ttattcaaag gagggattga tatgaggaaa
     1021 aaatttttta taggtattct tatagtttta ataatctctg tgatagctat acttaatata
     1081 aaaaatgata aaaatgtctt tattggagaa tcagaaaatt ggaaagctaa atttgtaact
     1141 actgaaggac actcaaaatt agaaataaaa tataaaaata gtaaagatgt agttgaacaa
     1201 aaatttaatt attcctatca atttatagat ggtgaagatg cagttgtagt tgtaaaaaat
     1261 gaaattttag aagcaggtca agaaaaagca ataaaaatac aaagaccagg tctttattca
     1321 aatagagaat ctagttacaa gctaattata tcttggaatg gaaatgagga aactataaac
     1381 ttgaaaaaga aataaccata ttatcaattt ttaaaaaatt attattcaaa ttcttataaa
     1441 aagagtgttt agaaaaatga aacactcttt tttgtataag tttttgaaaa ctataaatga
     1501 aatatatcaa aatcgttcga aaaattactg aaataaactc ttaaatatat tataaattaa
     1561 ggtatattat acatgaattt attgggagtt tatgagtttt aaaattggaa accaaacaat
     1621 aagggctaaa aatactttaa ggaaaatata taaagttcta taaattatca aaaatatttc
     1681 gcaaaaattg ataattatta caaataaatt gataatacta ataatattag aaatatcgaa
     1741 attgaacaaa ctaggattaa agctcaatta gaaaaatcca ctaatcctga gaatgctttg
     1801 ttattctcat ttattactgt tgttttttca ttatttgcta atttattttt cagttcatta
     1861 aatgttaaat ataactctat aaatttaatt ttacagttaa tatgtattat agttcttata
     1921 tttatatata ttaatacatt tttatatcgc ctcttcaatt tgagccccat cattatataa
     1981 aattaaccta cttgatatct taatttaata tatgtacact attcatatct taatagtcaa
     2041 tattattcat ttttaatagc tctttttaga tgtcagaatt attatatttt gaaatttatt
     2101 aaatttttgc attaaaaaaa ctagaaatta atttaagtct tgaattactt ataactttct
     2161 acgtatctac ctttatattc ttactctgat tttatatcta atattaactc ttcatcaaag
     2221 ctattaaata tacctctaat tgagtcaatt atttcactta cttcaccttt aatttttata
     2281 ttaacttcaa ccatttcaaa tctcatcttt ttatcttata atttctataa gtttttttat
     2341 ttattgtgtt gcttactttg accagcactt ttttatttaa tagtctaaat gatatttttt
     2401 accagtttta atatccttaa atactatatt tactaaaaac ttataatttc ttttaataca
     2461 ttcttattac taataacaat actcaacaat tttatcgcct tttttcaaat atgatttaac
     2521 ttttttattc ctaattattt aaaaatagtt gtccaatttt cttctatgag aaagtgctaa
     2581 gtattagcaa cttctctatt ctcttaactt tctactgtct caactttctt catagctata
     2641 ttaatagcta cttctttagc tacttcattg aactcttccc atcttctcct attttcttca
     2701 tcagatatac gtggatatac tatataaact tctgtgtttt gattagctat aattttttca
     2761 tcatattcta tatttttttc tttatcatat ttgtatggtt taaattgttg tagtattttc
     2821 ataacatcac cccttgttat aaaatatgaa ctcataaact tgtcttatac ttatttaatt
     2881 gttacaattt ttacttaaaa tcactttata ttctatattt taaagctaaa tcctttacaa
     2941 aagtaacata ttcttctata agtttcttat cctcttatat agtatctagt ttgtttaact
     3001 tatctctttt aaacttacat acgccttctt ctgccattcg tcttttatta attgttaaca
     3061 ttgtttcaag agacacacca aaactcttgt taagaagctc ttagctctca ttagtaaaat
     3121 attttacata acttaaatca ccttgacctc tagcaatttt aactgttaat agacttgttt
     3181 cttttttcca atgtattata tttaatataa caacatcttt tattatttta acttctattt
     3241 ttacatctaa tgccatatta ttgctttatt aatttgtatc cttaaatctt aaattttcta
     3301 ttaatacatc ttctatacag cttagtttct ctcgcttaat cttgaaatat attttctcta
     3361 aattgtcaaa ttgttcccaa gttttatcaa tatctaatat tttgcagtgt ctatttgcac
     3421 atctttcgat ccaaaggtat aattgactag aatgttttga aatcaactga ctattagtag
     3481 gttagttctt aaattctttc aaatactcga attgtaataa aacataattt acattctctt
     3541 tatttctatt gaagttagtt tatatattgt ttacatcatt ttcatatata tctgctagtt
     3601 gctatgcatt taaaattctc ttattatttc tttatattac ttgtaaatta ttcatcctca
     3661 tcatcctctt aattaaattt ctatcttaga aatttaattt gtaaaaaaat tttctatatc
     3721 ataatcaagt atcttagata gtttataggt aacatatcaa ctctaattga atattacccc
     3781 ttcctgtact taaaataagt tgatgcattt ttaaaaccta actcttttgc aacactttgt
     3841 aagtataaat tttatgtatg tcttcttttt tataaaatca tagtgtatct ttttcatata
     3901 ttcaccttaa ttgctatatt tcaataacaa tatttccaaa acagaaattt ttcgaggtaa
     3961 ttatgtatag atgtaaatca aagaattaaa tatactaggg aaaatatgaa tagttctcaa
     4021 aaagaattgc ttgaaaaaac aaatataaat acaagtgtta tgaatagaat ctggtgaaag
     4081 accaacaaga gacgatgggt taataatatt tgctaaaatt tttggtttat atactgatta
     4141 tgttcttggt ttatcagata cagaaaaact aaatattggc aattaaaact gaattgattg
     4201 tattatatgt gtgatgaata taaatataga attttttgag aagcttgaaa tagcttagaa
     4261 aaaataagag attcactcaa gaataagtta ctaaagatta aaaaataaca aaagtatcta
     4321 ctaaaggata tgaaaatggt ttaagagagt taagtctgga aatatttatg tgtattcttt
     4381 aaataaaaat ttatttttta aatgataatt aaatttttac tgatatggct atgcttttaa
     4441 aagtcataac cttattttga tattagatct gtctttacat accacttagt taatataaaa
     4501 ctaaatatag cttgtaactc ctttgatgca cttaaaagct ttacatacca cttagttaat
     4561 ataaaacgaa tttagctata gaagcatcaa attgtggcac agcactttac ataccactta
     4621 gttaatataa aacctttaaa gacaaaacgt cgtataatta aatcatagca actttacata
     4681 ccacttagtt aatataaaac cttataattc tttaagtact agactgagca atttaatctt
     4741 tacataccac ttagttaata taaaaccatc ccattcagca acaacagtcg ctaaatcttc
     4801 tgcctttaca taccacttag ttaatataaa acttttagta tattttttag gtctgccctc
     4861 tttaaaactc tttacatacc acttagttaa tataaaacac gaggttatag ttaattttgt
     4921 cgtgggagtt tataacttta cataccactt agttaatata aaacaattta tatatatata
     4981 tatatatatt aaagtcagac ccctttacat accacttagt taatataaaa cttgttgttc
     5041 agcattagca atcatatcat ctattccttt ctttacatac cacttagtta atataaaacc
     5101 tgtaccatca gagacagtca ttaaaagatt tataaacttt acataccact tagttaatat
     5161 aaaacttata aattgtctct gtacccattt tattcaatgt cgtactttac ataccactta
     5221 gttaatataa aaccatgaaa aaatgggtaa ttcaaactct tttattttct ttacatacca
     5281 cttagttaat ataaaacgtt ggagaaaata atccttctta tgatttgcca agcggcttta
     5341 cataccactt agttaatata aaaccagcgg atgaattatt tatgttaatt ggagatggag
     5401 actttacata ccacttagtt aatataaaac cccaaaataa attgagtatt tccaacactt
     5461 acatctatac aattctctca aatttgcagt gaaccatgag tagtgcaaat gataacattt
     5521 atcacatacc ctcaatgcct tatatttcaa ctgttaggcc ctattttatc aaaaatatcg
     5581 ctcactgcaa aactatttat aattttataa tattatgaat atattatttt taaatatctg
     5641 taccaatttg tagtataata aaatcaagaa aataatttac tcctataaag agtgattatt
     5701 tttaagtgaa aatattattt ttttaaatca tccttattgg cgtttgggag atttttattt
     5761 tatcataaat ataaactgat ataacaccag ctgacatgct tgctgctttc gattattatt
     5821 cttgctacaa ttattataac atataaaact tacttatttt taccaaatat tttatacaaa
     5881 caataaatat taacttatga aatatctact catttacaga tatttcataa gttaatagct
     5941 ctataataaa atttttatca ttgtttataa aaaattttac tttgcatttt tttataaaca
     6001 acagttttat ttataatgtt ttgtggtata ataaaagcaa gaagaactac aatctatttt
     6061 gcgttagagt ggagttcatc ataaacagag tttatttttt ggatttaaat ataaatttaa
     6121 attcaactcg taagtcactc tttgtgctga actataccca ctgttttata cagttaaaac
     6181 atgtaaaagt ggttataaag tactagtgtc aatcattagt acttttttta ttatattcat
     6241 ataattaata gctatatttt aaagtttact atctaaaaaa tagcac
//
LOCUS       DAMJYN010000145         6238 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.151, whole genome shotgun sequence.
ACCESSION   DAMJYN010000145 DAMJYN010000000
VERSION     DAMJYN010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6238)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6238)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6238
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.151"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            187..1209
                     /locus_tag="PC466_003484"
     CDS             187..1209
                     /locus_tag="PC466_003484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDF2770835.1"
                     /translation="MKNLLEIQKKLIPQAIELMERRYSILRQISLSEPIGRRTLSNVL
                     EISERIIRSETEFLKEQGLIDVAVSGMTITKEGSDLLDKLKDIMSDIMGLSKLQDRVR
                     EKLGIKRVILVPGSCDENGSLLKDVTRYGCEYFLGILKDGDIVSITGGSTMLEFSNVI
                     KTDKRYPNSTIVPARGSMGTDVEMQSNNIVASISKKLHSNCKLLHIPDELDESAMKTL
                     SQVPEIKTTLEYIKRTDILVFSIGRADVMAKRRKLPEDKVDEILSKNAVGEAFGYYFN
                     KDGEIVYKLNTVGIDLETVKQVKETIAIFAGTEKVEALLAISNMHKNMVLVTDEESAY
                     KILSLL"
     gene            1269..2276
                     /gene="gap"
                     /locus_tag="PC466_003485"
     CDS             1269..2276
                     /gene="gap"
                     /locus_tag="PC466_003485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HDF2770836.1"
                     /translation="MVKVAINGFGRIGRLALRKMMEQQDKFEVVAINDLTDAKMLAHL
                     FKYDTAQGRFNGEIEVKEGAFVVNGKEIKVTAERNPADLPWAELGVDIVLECTGFFTS
                     KDKAEAHIQAGAKKVVISAPATGDLKTIVFNTNSDILDGSETVISGASCTTNCLAPMA
                     KVLNDKYGIEKGLMTTIHAYTNDQNTLDGPHPKGDLRRARAAAGNIVPNTTGAAKAIG
                     LVIPSLKGKLDGAAQRVPVVTGSITELVCTLGKNVTVEEINAAMKEASNESFGYTEEM
                     LVSSDIIGISYGSLFDATQTKVMEVDGKQLVKVVSWYDNEMSYTSQLIRTLGYFAQLA
                     K"
     gene            2498..3700
                     /locus_tag="PC466_003486"
     CDS             2498..3700
                     /locus_tag="PC466_003486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HDF2770837.1"
                     /translation="MSMLNKKTIEDIDVCGKKVLVRCDFNVPLQDGVITDENRLNGAL
                     PTIQYLISKGAKVILCSHLGKPKGEAKPELSLAPVAKRLSEMLGKEVVFAADDNVVGE
                     NAKKATEKMENGDVVLLENTRYRKEETKNEENFSKELASLAEIFVNDAFGTAHRAHCS
                     TVGAGEFLQERVCGYLIQKELKFLGEAVANPVRPFTAILGGAKVSDKLAVINELLEKV
                     DNLIIGGGMAYTFLKAQGYEVGTSLLEIDKVEYAKEMMEKANNKGVNLLLPVDVVMAD
                     HFAPDATPIVTEDANVKEDYMGLDMGPKTIANFVKTIKESKTVVWNGPMGVFEFENFA
                     NGTLSVARAMAELTDATTVIGGGDSAAAVNQLGFGDKMTHVSTGGGASLEFLEGKELP
                     GIAALDNK"
     gene            3726..4469
                     /locus_tag="PC466_003487"
     CDS             3726..4469
                     /locus_tag="PC466_003487"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HDF2770838.1"
                     /translation="MRKPIIAGNWKMHKTIKEALEFVNEVKDKVNSDKVEAVICAPFT
                     LLKDLKEATKGTNIKIGAQNMHFEEKGAFTGEVSPLMLKEIDMDYVVIGHSERRQYFN
                     ETDETVNKKVLKALEVGIDPILCVGETLEQREAGKTKDVCKVQVEKALENVLKDDLSK
                     VVVAYEPIWAIGTGKTATAEDANDVISYIREVIKGLYGELANEVRIQYGGSVKPSNVA
                     EIMGQSDIDGALVGGASLASNDYLDLVNF"
     gene            4478..6010
                     /locus_tag="PC466_003488"
     CDS             4478..6010
                     /locus_tag="PC466_003488"
                     /EC_number="5.4.2.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003228330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-independent
                     phosphoglycerate mutase"
                     /protein_id="HDF2770839.1"
                     /translation="MMKKPVALIIMDGFGYNKDVKGNAIAESKTPNLDRIKKEYPNTL
                     INASGLDVGLPDGQMGNSEVGHTNIGAGRIVYQDLTRITKSIKDGDFFANKVLCEAMD
                     NAKENSLHVMGLLSDGGVHSHIDHLKAIIKMAKDKGVQKVYVHAFTDGRDTDPQSALE
                     YAKEVQASMDEIGVGEFATVSGRYYAMDRDKRWERVELAYNAMVRGIGEKANSIEEAI
                     QNSYDDGKNDEFIMPTVIMKDDKPVGSIKENDSIIFFNFRPDRARQITRALVCEEFDG
                     FKREDIKNFFVCLTEYDITIENVHIAFGPQSLANTLGEYLAKNGKTQLRAAETEKYAH
                     VTFFFNGGVEEPNKGEERLLIPSPKVATYDLKPEMSAYELTDKALDKLGEDKFDFIVL
                     NFANPDMVGHTGSIEAAIKAVETVDTCVGKLIDKIVELGGSAIITADHGNAEYMLDPE
                     TGKTVTAHSINPVPFIVVGQEYESAKLLDGGRLSDIAPTVLDMMKLEKPEEMTGHSLI
                     SK"
BASE COUNT         2490 a          726 c         1255 g         1767 t
ORIGIN      
        1 taaaaagaaa aaatactgtg atttgaaaat ggtggagaaa tattttataa aataaaaaaa
       61 taaaaaagtt tttgaaaaac tattgaaatc tatacgcaaa tcctataaaa taaaaatatc
      121 ttgtgggact taaataaaca ctagggacaa aaaaagtccc gaaaggaaag caataaggag
      181 tatgttatga agaacttatt agaaattcaa aagaaattga ttccacaggc aattgaactt
      241 atggaaagaa gatactctat tttaagacaa atatctttaa gtgaaccaat aggtaggaga
      301 acattatcaa atgtattaga gattagtgaa agaataatca ggtcagaaac tgagttttta
      361 aaagaacaag gacttataga cgtagctgta tctgggatga ctatcactaa agaaggttct
      421 gatttgttag ataaacttaa ggacatcatg agtgacatca tgggattgtc taagttacaa
      481 gatagagtca gagaaaagct tggaataaaa agggtaatac tagttcctgg aagctgtgat
      541 gaaaatggaa gtttactaaa agatgtaact agatatggat gcgagtattt cttaggcatt
      601 ttaaaagatg gagatatcgt ttcaataaca ggaggaagca ctatgttgga gttttcaaac
      661 gttattaaaa ctgataagag atatccaaac tctacaatag ttccagctag aggaagtatg
      721 ggaactgatg tagagatgca atctaacaat atagttgctt caataagtaa gaaattacat
      781 tctaattgca aacttttaca tataccagat gagttggatg aaagtgcaat gaaaactctt
      841 agccaagtgc cagagattaa gacaactttg gagtatatta aaagaacaga cattttagtt
      901 tttagtatag gtagagcaga tgtcatggca aagagaagaa aacttccaga agacaaggtt
      961 gatgagatat tatctaaaaa tgcagttgga gaagcatttg gatattattt caacaaagat
     1021 ggagaaatag tttacaaact gaacactgtt ggaattgatt tagaaacagt taaacaagta
     1081 aaagaaacta ttgcaatctt tgcagggact gaaaaagtag aagccttatt agctatatca
     1141 aatatgcata aaaacatggt tcttgtaaca gatgaagaaa gtgcttataa gatattgtca
     1201 ttattataaa agtcaagacc tagcacagag ctagaaaaca tacatttact ttataggagg
     1261 tagcgaaaat ggttaaagta gctataaatg gatttggaag aataggaaga ttagcattaa
     1321 gaaaaatgat ggagcaacaa gataagttcg aagttgttgc aataaacgac ttaacagacg
     1381 ctaaaatgtt agctcattta tttaaatatg atacagctca aggaagattt aacggagaaa
     1441 tagaagttaa agaaggtgct tttgtagtaa acggaaaaga aataaaagta acagcagaaa
     1501 gaaatcctgc tgacctacca tgggctgaat taggagtaga tatagtatta gaatgtacag
     1561 gattctttac atctaaagat aaagctgaag ctcatataca agcaggggct aagaaagttg
     1621 ttatatctgc accagctact ggagatttaa aaacaatagt attcaacaca aacagtgaca
     1681 tattagatgg ttctgaaaca gttatatcag gagcttcttg tactactaac tgtttagctc
     1741 caatggctaa agtattaaat gataaatacg gtatagaaaa aggattaatg actactatac
     1801 atgcatacac taatgaccaa aatactttag atggtcctca tccaaaaggt gatttaagaa
     1861 gagctagagc tgctgctgga aacatagttc caaacactac aggagctgca aaagcaatag
     1921 gcttagtaat accttcatta aaaggaaaat tagatggggc agcacaaaga gtaccagttg
     1981 taactggttc aataactgaa ttagtttgta cattaggaaa aaatgttaca gttgaagaaa
     2041 taaatgcagc tatgaaagaa gcttcaaacg aatctttcgg atatactgaa gaaatgttag
     2101 tatcttctga cataatcgga ataagctacg gttcattatt tgacgctact caaacaaaag
     2161 ttatggaagt agatggaaaa caattagtta aagttgtttc ttggtatgat aatgaaatgt
     2221 cttatacttc tcaattaata agaactttag gatactttgc acaattagca aaatagtcag
     2281 ttttgagaaa atagaaaagt agattgacaa agtccgagtt tgtagtttaa tactacggac
     2341 tcaggacttt ttttaagaaa aaatatataa aatacaccta aataatgtta catactatat
     2401 ataaaaatat gataatatga tatatttaat agggtaaaag tatgtactat attatacttg
     2461 gcaataaaaa attactttat taaaaggaga gatatttatg tcaatgctta acaaaaaaac
     2521 tatagaagat attgatgtgt gcggaaaaaa agtattagta agatgtgact ttaatgtgcc
     2581 attacaagat ggtgtaatta ctgatgaaaa tagattgaac ggagctttac caactattca
     2641 atatttaatt tctaaagggg caaaagttat attatgctct cacttaggaa agccaaaagg
     2701 agaagctaaa ccagaattat ctttagcacc agtagcaaag agattatctg agatgttagg
     2761 aaaagaagtt gtatttgcag cagacgataa tgttgtagga gaaaatgcaa agaaagcaac
     2821 tgaaaaaatg gaaaacggag atgtagtatt attagaaaat actagatata gaaaagaaga
     2881 aactaaaaac gaagagaatt tctctaaaga actagcatca cttgctgaaa tatttgtaaa
     2941 tgatgcattt ggaactgctc atagagcaca ttgctcaaca gttggtgcag gcgagttttt
     3001 acaagagaga gtttgtggat acttaattca aaaagaatta aaattcttag gagaagctgt
     3061 tgcaaaccct gtaagaccat ttacagctat acttggagga gctaaagttt ctgataaatt
     3121 agctgttata aacgaattat tagaaaaagt tgataatcta ataataggtg gaggaatggc
     3181 ttatacattc ttaaaagctc agggttatga agtaggaact tctttacttg aaatagataa
     3241 agttgaatat gctaaagaaa tgatggaaaa agctaataat aagggtgtta acttattatt
     3301 accagtagac gttgttatgg cagaccactt tgcaccagat gctactccaa tagtaacaga
     3361 agatgctaat gtaaaagaag attacatggg actagatatg ggacctaaga ctatagcaaa
     3421 ctttgtaaaa actataaaag aatcaaaaac tgtagtatgg aatgggccaa tgggagtatt
     3481 tgaatttgaa aactttgcaa atggtacatt atcagtagct agagctatgg cagagttgac
     3541 tgatgcaact actgtaattg gcggtggaga tagtgcagca gcagttaatc aattaggatt
     3601 tggtgacaag atgactcacg tatcaacagg tggaggagca tcactagaat ttttagaagg
     3661 taaagaatta ccaggtattg cagcattaga taataaataa actaatatat agaggagatt
     3721 gtaaaatgag aaaacctata attgcaggaa actggaaaat gcataaaaca ataaaagaag
     3781 ctttagaatt tgtaaatgaa gttaaagata aagtaaattc tgataaagta gaagctgtta
     3841 tatgtgcacc atttacttta ttaaaggatt taaaagaagc tactaagggt acaaatataa
     3901 agataggtgc tcaaaatatg cactttgaag aaaaaggagc atttacagga gaagtttcac
     3961 ctcttatgtt aaaagaaata gatatggact atgttgtaat aggacattca gaaagaagac
     4021 aatacttcaa tgaaactgat gaaactgtaa acaagaaagt tttaaaagca ttagaagtag
     4081 gaatagaccc aatattatgt gttggagaaa ctttagaaca aagagaagct ggaaaaacta
     4141 aagatgtttg taaagttcaa gttgaaaaag ctttagaaaa tgttcttaaa gatgatttat
     4201 caaaagtagt tgttgcatat gagccaatct gggctattgg aactggtaaa actgcaactg
     4261 ctgaagatgc taatgacgtt atatcttata taagagaagt tataaaagga ttatatggag
     4321 aattagctaa tgaagttaga atacaatacg gtggaagtgt taaaccttca aatgtagccg
     4381 aaataatggg tcaaagtgat atagatggag ctttagtagg tggagctagt ttagctagta
     4441 atgattacct agaccttgtt aatttctaag gagtgaaatg atgaaaaaac cagttgcttt
     4501 aattattatg gacgggtttg gatacaataa ggatgttaag ggaaatgcaa ttgctgagtc
     4561 caaaactcct aatttagata gaataaaaaa agagtatcca aacacattga taaatgctag
     4621 tggtcttgat gttggtctac ctgatggtca aatgggaaat tcagaagttg gacacactaa
     4681 cataggtgca ggtagaatag tatatcaaga tttaactaga ataacaaaat ctataaaaga
     4741 tggtgacttt tttgctaata aagttttatg tgaagcaatg gataatgcaa aagaaaattc
     4801 tcttcatgta atgggacttt tgtctgatgg aggagtacat tcacatatag accatcttaa
     4861 ggctataatc aaaatggcaa aagataaagg cgtacaaaag gtgtatgttc acgcatttac
     4921 tgatggtaga gatactgacc ctcaaagtgc attagaatat gccaaagaag tacaagctag
     4981 tatggatgaa attggagtag gtgaatttgc tacagtttct ggtagatact acgctatgga
     5041 tagagataag agatgggaaa gagtagaact tgcatacaat gccatggtta gaggtattgg
     5101 tgaaaaagca aattctattg aggaagctat tcaaaactct tatgatgatg gaaaaaatga
     5161 tgagtttata atgccaacag ttattatgaa agatgataaa ccagttggaa gtataaagga
     5221 aaatgattca attatattct tcaactttag accagataga gctagacaaa taactagagc
     5281 tttagtttgt gaagagtttg atggatttaa aagagaagat attaaaaact tctttgtatg
     5341 cttaacagag tacgatataa ctatagagaa tgtgcatata gcatttggac ctcaatcttt
     5401 agccaacact ttaggtgagt atctagctaa aaatggaaaa actcaactta gagctgctga
     5461 aactgaaaag tatgcacatg taactttctt cttcaatggt ggagtagaag agccaaataa
     5521 aggtgaagaa agactattga taccttctcc aaaggttgca acttatgatt taaaaccaga
     5581 aatgtcagca tatgaattga cagataaagc tttagataaa ttaggagaag ataagtttga
     5641 ctttatagta ttaaactttg caaatcctga tatggtaggt cacacaggaa gtatagaagc
     5701 ggctataaag gctgttgaaa ctgtagatac ttgtgtagga aaattgatag ataaaatagt
     5761 agagttaggt ggaagtgcaa taataactgc tgaccacgga aatgctgaat atatgttaga
     5821 cccggaaaca ggaaaaactg taacggctca ctctattaat ccagtaccat ttattgtagt
     5881 tggtcaagaa tatgaaagtg caaaattatt ggatggagga agattatctg atatagcacc
     5941 gactgtttta gatatgatga agttagaaaa gccagaagaa atgactggtc attcacttat
     6001 ttcaaaatag tcgattctga taagtagaga ataatatata aactacaata taaatttaaa
     6061 aataatgcag tttaggttta ttttgtaaag tttagacttt atgacataag atttagattt
     6121 tgtaagttct ggatattgta aggtgtagat gaaggtatat tttataaaat ttacaagata
     6181 gacaatttat aaaataaaaa attataatat agataataat gtaaataatg atataaat
//
LOCUS       DAMJYN010000146         6209 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.152, whole genome shotgun sequence.
ACCESSION   DAMJYN010000146 DAMJYN010000000
VERSION     DAMJYN010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6209)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6209)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6209
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.152"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            333..1700
                     /locus_tag="PC466_003489"
     CDS             333..1700
                     /locus_tag="PC466_003489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase"
                     /protein_id="HDF2770840.1"
                     /translation="MGLKEFDFIEESIDMLRTMSPTLETISDEIEEYFENILDEKNQE
                     YINVTSRIKSESSLREKIIRNRYLKKYGEASNLIHNVSDLIGLRIECRFIEDENKIYR
                     LLRRYFNKTDDKINYYNKENKNIKLKLSERQPNKQKNGFEIYKIDGVFAYLDREVKFE
                     LQIKSLVNVFWSEIEHKIIYKNNTYLLADKFIKDMMDSIKNNLTMIDNQLLSIYKNFH
                     SGKSFNMKVSKKEIEKLFAKLVYDAFSEKMNKSIGFVVDFKKPCETILNYSFNKQDIS
                     DEVLGNFMLDEFARLNEIVNKDIDFNEQIEFEREPTFDDKFCKDLGNHFRSRLNTEFP
                     WNLFFRILFEIEPYNNTKDFENFVEFIKENVLLEENREQLLCQFEEDSKLIIEDIYDC
                     IFNSISEIDSVEILYNYNLEKINFTSSEIINCICREYECYGEYLEEKEKLMNTFKEKI
                     IQIFE"
     gene            1725..2333
                     /locus_tag="PC466_003490"
     CDS             1725..2333
                     /locus_tag="PC466_003490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor guanylyltransferase"
                     /protein_id="HDF2770841.1"
                     /translation="MRHFSNIYELSKIILEEAICIEKTGVILAGGKNSRMGRDKAFLE
                     LHDKLFIEIAIEAFKNFDELIIISNNEELYSKYDIKVYNDIVKDVGPIGGIYTALEYA
                     KYDIVTIACDMPYLNNQIVERIANKMNDKSVISVTNGKLQPLCSGYKKSIINKVSLCI
                     RENDLKLRSFIDKIDKSYIYFDEEDLFLNVNTVDEYEKLTKV"
     gene            2381..2752
                     /locus_tag="PC466_003491"
     CDS             2381..2752
                     /locus_tag="PC466_003491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HDF2770842.1"
                     /translation="MNLLKCDSWAVILNNSDKESKAYKILDELKRNMYKVVAIDEEKK
                     PIEGIDVYECLKDVPHNIDVVAIIDKQSKMDVILEEVELLDIQNMWFEKGSFSEMMIK
                     KTKDLKLNIEYNLSLYDELTR"
     gene            2931..3269
                     /locus_tag="PC466_003492"
     CDS             2931..3269
                     /locus_tag="PC466_003492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HDF2770843.1"
                     /translation="MLIVTTEKVEGKKISKVLGLVRGSTIRAKHVGKDIGASFKNLVG
                     GELTGYNEMLTEARQIAIGRMVEDAEAKGANAVIAFRLSSASVMQGAAEMLAYGTAVV
                     LEDDNSILEK"
     gene            3736..4239
                     /locus_tag="PC466_003493"
     CDS             3736..4239
                     /locus_tag="PC466_003493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MogA/MoaB family molybdenum cofactor
                     biosynthesis protein"
                     /protein_id="HDF2770844.1"
                     /translation="MFNVAIITLSDKGYEGKREDITGKKLTEFVENTGAYKVTEYVLI
                     KDDKEMLKENIIRLCNSNKIDLILTNGGTGFSKRDITPEATKEVLEKEIPGLSEYMRM
                     KSTEITKKAILSRGVSGIRNNSIIINLPGSPKGAVENLSFIIDVLDHGIEVLRGEATE
                     CATKKSE"
     gene            4286..5245
                     /gene="moaA"
                     /locus_tag="PC466_003494"
     CDS             4286..5245
                     /gene="moaA"
                     /locus_tag="PC466_003494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP 3',8-cyclase MoaA"
                     /protein_id="HDF2770845.1"
                     /translation="MIDKYGRKIDYLRISLTDKCNLRCVYCMPPDVKFDKNYINENLS
                     FEDYKFIIKAMAEQGITKIRFTGGEPLLYPKLNELIKFTKEECGINNIGMTTNAIGLS
                     DRIFELEKCGLNKVNISLDSLKEYKYKSVTRGGNLKDVLKSIESCLNLGIKVKLNCVA
                     ISGFNDDELKDFMFLTVKSPIDVRFIELMPLGEANRVYKKGYFNVKEMIEKIYGLYKV
                     KNDEKSTAEYYMFKGAKGRIGIITPLSCSFCNTCNRIRLTSSGAIKLCLHSKEEIDIK
                     PFLHKPLLFRESMKDIIKQKPEKHHLIENKCSDTNRRMYEIGG"
     gene            5249..5719
                     /gene="moaC"
                     /locus_tag="PC466_003495"
     CDS             5249..5719
                     /gene="moaC"
                     /locus_tag="PC466_003495"
                     /EC_number="4.6.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic pyranopterin monophosphate synthase MoaC"
                     /protein_id="HDF2770846.1"
                     /translation="MLTHINEKGYAKMVDISEKDDTKRTAVATATITLSKEALEKVKN
                     GQIKKGDVLSVAQVAGIMGAKNTSSNIPMCHQIKLVGCDLEFDVDDYMSAIKIYATCK
                     SLGKTGVEMEALNACSLAALTIYDMCKAVDKKMVISNIHLVEKTGGKSGDFKFE"
     gene            5755..6186
                     /locus_tag="PC466_003496"
     CDS             5755..6186
                     /locus_tag="PC466_003496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MOSC domain-containing protein"
                     /protein_id="HDF2770847.1"
                     /translation="MAKVVSINISEKKGVIKVPVPCAELKINHGIVGDAHAGNWHRQI
                     SLLGKESIDKMKMKGFDQLKYGDFAENVTTEGIEVFSLPVGTKLRIGQCEVEVTQIGK
                     KCHNGCEIKKLTGDCVMPREGIFVKVLKEGIINVNDSIDVI"
BASE COUNT         2617 a          506 c         1127 g         1959 t
ORIGIN      
        1 gcattgattt atcgtttttt atatttcata taacaatgca aaaaataatt tttatatagt
       61 aaatgacaaa agtttacaat aaatgtatat tttcttactc attccttaaa attactcatt
      121 tagtttaata actctcattt catatgtaaa gttggtaaaa aaattaaaat taaaagtaaa
      181 aaactaaata aattaatgtt aatttgaaat atatatgaag gtttttggag aatacttact
      241 tatgatagga aaaaatgtta aaataatagt gtaatcaaat ataaaggact gaaataatta
      301 acagttatta aatattagga gtgtaaaaat ttatgggatt aaaagaattt gattttattg
      361 aagagtctat tgatatgttg aggacaatgt caccaacatt agaaactata tcagatgaaa
      421 tagaagagta ttttgaaaat atcttggatg aaaagaatca agaatatata aatgtaacct
      481 ctagaataaa atcagaatca agtttaagag aaaagataat tagaaataga tatttaaaaa
      541 aatatggaga agcaagtaat cttattcata atgtttctga cttaataggc ctaagaattg
      601 agtgtagatt tattgaggat gaaaacaaaa tatatagact tttgagaaga tattttaata
      661 aaacagatga caaaataaac tattataata aagagaataa gaatattaaa ttaaaactat
      721 ctgagaggca acccaataag caaaaaaatg gatttgaaat atataaaata gatggagttt
      781 ttgcgtattt agatagagaa gtaaaatttg aacttcaaat taaatctctt gtaaatgtgt
      841 tttggagtga aatagaacat aaaataattt ataaaaataa tacatattta cttgctgata
      901 aatttataaa ggatatgatg gactctataa agaataatct tactatgata gataatcagc
      961 ttttaagtat ttataaaaac tttcattcag ggaagtcttt taatatgaaa gtaagtaaaa
     1021 aagaaattga aaaattattt gcgaaactag tctatgacgc tttttctgaa aagatgaata
     1081 aaagtatagg ttttgttgta gattttaaaa aaccatgtga aactatattg aactattctt
     1141 ttaataaaca agatataagt gatgaagttt taggtaattt tatgcttgat gagtttgcaa
     1201 gattaaatga aattgtaaac aaggatatag attttaatga gcaaatagaa tttgaaagag
     1261 aaccaacatt tgatgataag ttttgtaaag acctaggaaa tcattttaga agtagattaa
     1321 acacagaatt tccatggaac ctatttttta gaatattatt tgaaatagag ccatataaca
     1381 ataccaaaga ctttgaaaac tttgtagagt ttataaaaga aaatgtgcta ctagaagaaa
     1441 atagggagca attattatgc caatttgaag aagatagcaa gcttataatt gaagatatat
     1501 atgattgtat atttaatagt ataagtgaga ttgatagtgt tgaaatttta tataactata
     1561 atcttgaaaa aataaacttt acatcaagtg aaatcataaa ttgtatatgt agagaatatg
     1621 agtgttatgg tgaatactta gaagaaaaag aaaagcttat gaatacattt aaagaaaaga
     1681 ttattcaaat ctttgagtaa taggtcaatg ctgaagtggc gctaatgcgc catttttcaa
     1741 atatatatga attaagtaaa attattttgg aggaggcgat ttgtatagag aaaacaggtg
     1801 taattttggc agggggaaaa aattctagaa tgggtagaga taaagccttt ttagagttac
     1861 atgataagct ttttattgaa attgcaatag aagcatttaa aaactttgat gagttgataa
     1921 taatatctaa taatgaagaa ttatattcta aatacgatat taaagtttat aatgatatag
     1981 taaaagatgt tggtccaatt ggaggaatat atactgctct tgaatatgca aagtatgata
     2041 tagttacaat tgcatgtgat atgccatatc taaataatca aatagtcgaa agaatagcta
     2101 ataaaatgaa tgataaaagt gtgatttcag tgacaaatgg aaagttacaa ccattgtgtt
     2161 ctggatataa aaagagtata ataaataaag tatctttatg tataagggaa aatgatttaa
     2221 agctcagaag ctttatagat aaaatagata aaagttatat atactttgat gaagaagatt
     2281 tatttttaaa tgtaaacact gttgatgagt atgaaaaatt aactaaagtt taattagcta
     2341 tggttgtaaa atagagtagg atttatatgg aggagagttt atgaatttac ttaaatgcga
     2401 ttcttgggca gtaatattaa ataatagcga taaagaaagt aaagcatata aaatattaga
     2461 tgaacttaaa aggaatatgt acaaagttgt tgctatagat gaagagaaaa aacctattga
     2521 aggaatagat gtgtatgaat gtttaaaaga tgttccacac aatattgatg ttgtagctat
     2581 tattgataaa caatctaaga tggatgtgat tttagaagaa gtagagcttt tggatataca
     2641 aaatatgtgg tttgaaaaag gaagctttag tgaaatgatg attaaaaaga ctaaagattt
     2701 aaaattaaat atagaatata atttaagttt atatgatgag ttgactagat aaaattatat
     2761 ttcttaataa taaaaatata attagttaat aaaacatatt attttatagt atagattggt
     2821 taataaaagt acagattggt taatgaaaca ttaaattaca atatttgtta aaagaattgt
     2881 gagttacatg atataatgta ttaaatagga tactaaggag ttgatatatt atgttaatag
     2941 taactacaga aaaagtagaa ggtaaaaaga tatcaaaggt tttaggatta gtgagaggaa
     3001 gtacaataag agcaaaacat gttggaaaag atataggagc aagttttaag aatcttgttg
     3061 gaggagaact tactggatat aatgaaatgc tcactgaagc aagacaaatt gccataggta
     3121 gaatggttga agatgcagaa gctaaaggtg caaacgcagt aatagcattt agactgtctt
     3181 cagcttcagt tatgcaaggg gcagcagaaa tgcttgctta tggaacagca gttgttttag
     3241 aagatgataa tagtattctt gaaaaataaa atataaatag ttaaaaagag gcatctttta
     3301 aaaattttat ggatgccttt ttttatttga aaaaactaat ttgagaagaa attttaacta
     3361 ttatgacaat aaaattaggg tgatattata taaataagta aaattatatt atataatgta
     3421 tggtatagac tttaaaaatt ttatttgtag agaaaaatat ggacaatgtt ataataatta
     3481 tagaaattaa aagtacttac attcattatg tatgtgacat gtataattag ttttatattt
     3541 aatacagttt tgaagtaata tcttcatttt gagaacgttg gaataataaa aaatgtatgt
     3601 attataggtg atataaataa aaaataaata taatatgtta tattgctgat agaaaagaga
     3661 ataaaagaaa ataggtttta ttaaaagaga tttttattta taggacttaa tcaatgtata
     3721 gaggggtgag aacatatgtt taatgttgca attataacac ttagtgataa aggatatgaa
     3781 ggaaaaagag aagatataac aggaaaaaag ttaactgaat ttgttgaaaa tacaggagct
     3841 tataaagtta ctgagtatgt acttataaaa gatgataagg aaatgctaaa ggaaaatatt
     3901 ataagacttt gtaatagtaa taaaatagat ttaattctta caaatggagg tactggtttt
     3961 tcaaaaagag atataacccc agaagcaact aaggaagtgt tggaaaaaga aataccaggt
     4021 ctgagcgaat atatgagaat gaaatccaca gaaattacta aaaaggccat actaagtagg
     4081 ggtgtgagtg gaataagaaa taattctata ataataaatt tacctggaag tcctaaaggt
     4141 gcagttgaaa atctaagttt tataattgat gttttagacc atggcataga agttttaaga
     4201 ggagaagcta cagaatgtgc cactaaaaaa agtgaatagt atataatcta gatagataaa
     4261 aaatagacaa agaggtagat aaagtatgat tgataagtat ggaagaaaaa tagactacct
     4321 tcgtatttca cttacagata agtgtaattt aaggtgtgtc tattgtatgc caccagatgt
     4381 aaaatttgat aaaaattata taaatgaaaa tctaagcttt gaagactaca agtttattat
     4441 aaaggctatg gctgaacaag gtataacaaa aattagattt actggaggag aacctctttt
     4501 atatcctaaa ttaaatgagc ttataaaatt tacaaaagaa gaatgtggaa taaataacat
     4561 aggaatgact actaatgcta ttgggctttc tgatagaatt tttgagcttg aaaaatgtgg
     4621 cttaaataaa gttaatataa gtttagattc tttgaaggaa tataagtata aatccgtaac
     4681 aagaggagga aacttaaaag atgtcttaaa atcgattgaa tcttgtttaa acttaggtat
     4741 aaaagtaaag ttaaattgcg ttgctataag tgggtttaat gatgatgagc ttaaagattt
     4801 tatgttttta acagttaaat caccaattga tgtaagattt atagagctta tgccattagg
     4861 tgaggctaat agagtttata agaagggtta ttttaatgta aaagaaatga ttgaaaaaat
     4921 atatggttta tataaagtca aaaatgatga aaaaagtaca gcagaatatt atatgtttaa
     4981 aggagctaaa ggaagaatag gaattataac tccattaagc tgttcatttt gtaacacttg
     5041 taatcgtatt agacttactt ctagtggtgc aataaaatta tgtctacatt caaaagaaga
     5101 aatagatata aaaccatttt tacataaacc attgttattt agagaatcta tgaaagatat
     5161 aataaaacaa aaaccagaaa aacatcattt aatagaaaat aaatgtagtg atacaaatag
     5221 gcgtatgtat gaaattggag gataagtaat gttaacacat ataaatgaaa aagggtatgc
     5281 caagatggtg gacataagtg aaaaagatga tactaaaaga acggccgtag ctacagctac
     5341 aattactctt agtaaggaag cattagaaaa agtaaaaaat ggtcagataa aaaaaggaga
     5401 cgtattgtct gtagctcaag ttgcaggtat aatgggagct aaaaatacat cttcaaacat
     5461 accaatgtgc catcagatta aattagttgg atgtgattta gaatttgatg tagatgatta
     5521 tatgtctgct attaagatat acgcaacctg taaatctctt gggaaaactg gagtagaaat
     5581 ggaagcttta aatgcatgtt ctttagcagc acttacaatt tatgatatgt gtaaagcagt
     5641 tgataaaaaa atggttataa gtaatatcca tcttgtggag aagactggtg gaaaatcagg
     5701 agattttaag ttcgagtaaa ttaataatat attgggttaa aatttggagg aaatatggcg
     5761 aaggtagtgt caataaatat aagtgagaaa aagggtgtaa ttaaagttcc tgtaccatgt
     5821 gcagagctaa aaataaatca tgggatagtt ggagatgcac atgcaggaaa ctggcatcgt
     5881 cagataagct tacttggaaa agaaagcata gataaaatga aaatgaaagg ctttgaccaa
     5941 ttaaaatatg gagattttgc tgaaaatgta actacagaag ggatagaagt tttttccctg
     6001 cctgttggta caaagttaag aatagggcaa tgtgaagttg aagtaactca aatagggaaa
     6061 aaatgtcaca atggatgtga aattaagaaa ttgacaggtg actgtgtgat gccacgagaa
     6121 ggaatttttg taaaggttct aaaagaagga attataaatg tgaatgattc aatagatgta
     6181 atctaatgaa gtcactatta aaatataat
//
LOCUS       DAMJYN010000147         6162 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.153, whole genome shotgun sequence.
ACCESSION   DAMJYN010000147 DAMJYN010000000
VERSION     DAMJYN010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6162)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6162)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6162
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.153"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            31..744
                     /locus_tag="PC466_003497"
     CDS             31..744
                     /locus_tag="PC466_003497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2770848.1"
                     /translation="MINIIICEGKKSERVILNDYINTFFYNYNFEYNIKEFENGGDLL
                     KKYPNNVDIIFMDIDLNDENGFNVSKEIKKFDESVRIIFVSSSNKYIKKGYEIGVYRY
                     LEKPLKYSLFKEAISSYLKECYKNEAILSIKCKCKIYFIKVDDILYLEVLKNDLTIHT
                     EKGIYTFKNSMKEIESNLEEHNFFRCHKSYLINLMKVNMLDIENNIVFINQNSIIVSR
                     YKIKLLREKLNSCLVDVII"
     gene            1017..2789
                     /locus_tag="PC466_003498"
     CDS             1017..2789
                     /locus_tag="PC466_003498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2770849.1"
                     /translation="MENGKFQFFKGVRNCFNMIYLHDKRYLFISMFMAIFQGIVPSIS
                     LLVSQNIINNMQTFSKSVKEILVLLIMYLIINIIPSIFQSFYGYYRIKFNKNFEKHIE
                     TMMLEKSLTLSLKDFEDDNTYDMINRAQSQKGFNITILSENLISIIRESVSTLSLIVV
                     LSQFQLWLIIVVIVIPVLKSLYSIKLGKEQYDVSVNRTWKERKAWYIDYLLSKGYAYK
                     EIMVFRIGSKLINHYKKLKEDIISQDMNIAKKNFIATLLCTVLDSIVSAGIIGFIIIQ
                     GILKKILIGDATTYIQAVQSIKDNVESIFSLFSSVIQDLFYTDLLFKFLDYNCKEDSI
                     EHIKIFEKIGDINKIELINISYKYNHSSEYSLKNINLTLNKNDPIAILGKNGSGKTTL
                     LKILLGFYDDYEGDILINGKNLKDIEKDEYIRKVSCMFQDYIKYEATLKENVAMGDVY
                     KSNLEEKVKSKLKETKLKPSIYEEDGLETILGTWFGKKQLSMGEWQKVAISRTLMKDA
                     DMYIFDEPDSSLDSEAGNELLSLYKKTFENKIGIFITHHIQHAKKITNNIVVLENGKL
                     LESGRHDELMDKKGVYFNLFCNCK"
     gene            2811..4232
                     /gene="ccpM"
                     /locus_tag="PC466_003499"
     CDS             2811..4232
                     /gene="ccpM"
                     /locus_tag="PC466_003499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-rich peptide radical SAM maturase CcpM"
                     /protein_id="HDF2770850.1"
                     /translation="MNQKPFIHTFKAGKSYFIYDVNTDKILKVNAAVYNYLNKIEHNL
                     EKESDWNIEIEDEINTLINYGFLKNKRVNKTMHPETKYIKYHIENNLSSIILQVTQNC
                     NLRCDYCIYSGSYSNRVHTNKRMNIDVAKRSIDYLIKNSSQLNEVSVGFYGGEPLLEF
                     DLIKQIVEYVKVVGEGKEIYFNLTTNATLFNEEIIEFFVKNNITTMISLDGGKEIHDK
                     SRKFANTGEGSHDVVLKNVRYIKNKYPEYYKKNITFNTVINSENDYISIDDFISKNET
                     LKDSNFLASTLNNNYSDKEIVSSDEYILGKSYDRFLTLLNKLKFIKDESMSPLSRIER
                     ALLDDFRYEKNIEGRLELPDVWHHGGPCIPGAFRIFVTTDGEFFPCERVSESSKMGMI
                     GNLDSGVDIEKAEKLLNIGKLYEEQCSDCWAYSYCDICIAKIDDTKCNENEIKPHDCD
                     RIRHSTENNMKDYCVLKSLGYQY"
     gene            4261..5331
                     /locus_tag="PC466_003500"
     CDS             4261..5331
                     /locus_tag="PC466_003500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04066 family peptide maturation system
                     protein"
                     /protein_id="HDF2770851.1"
                     /translation="MEKVLIYPFNYNFFTILNHCNKISDIEINSLVSPSGWGLCNKEY
                     NVNNIITKVTNDFQSELKKNSLVWFVDSKENLDLEKFIIPKLKVALKEGKKILYTRDD
                     LNKISRYISHYEFKKINEWNLEKYEIRDIEGISQINTPIIFICGLYGGLDTFDVNIRI
                     GEELRKRGFSILQFGPKKESYLFKMIPIPEFMFDDSISSKTKIINFNHFIKDKEVEAK
                     PDLIIIEVPGELFPFSRKMVGNFGIRAFEISNAVINDCGILCIPSSIYDREYCEELKY
                     FIKGRHGINIDYFSIEKKVIDTYETEVKQKFSYMSLDENFFVEDIEDYEKTFFIHDNK
                     QLLELVDNIVNQLKEYAKVISI"
     gene            5347..5598
                     /locus_tag="PC466_003501"
     CDS             5347..5598
                     /locus_tag="PC466_003501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide maturation system acyl carrier-related
                     protein"
                     /protein_id="HDF2770852.1"
                     /translation="MNYTEKELLLENIFFDVTGINFNKNNNLKKELFFSPSLHIQPRE
                     LLLVFCEVIENFNIKIPEEKLLNRQFTSFDNVLKIINMV"
     gene            5649..5852
                     /locus_tag="PC466_003502"
     CDS             5649..5852
                     /locus_tag="PC466_003502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770853.1"
                     /translation="MSFGKRIEMNNIGVETRGVCTIMCPYTCKMMASSSCNCKNNDYN
                     ARGGSYNTYYNKLIHGQRTPDGM"
BASE COUNT         2547 a          517 c          951 g         2147 t
ORIGIN      
        1 taaaataaaa aattatataa ggggtgtaat atgattaata ttattatttg cgaaggtaaa
       61 aaatcagaga gggtaattct aaatgattat ataaatacct ttttttataa ttacaatttt
      121 gaatacaata tcaaagagtt tgaaaatgga ggcgatttat taaaaaagta tcctaataat
      181 gttgatatca tatttatgga tatagactta aatgatgaaa atggatttaa tgtttcaaaa
      241 gaaatcaaaa aatttgatga aagtgtaaga attatatttg tatcctcatc aaataaatac
      301 ataaagaaag gttatgagat aggagtttat agatatttag agaagccctt aaaatactct
      361 ctatttaaag aagcaatatc atcatattta aaagaatgct acaaaaatga agctatttta
      421 tctataaaat gtaaatgcaa gatatatttc ataaaggtag atgatatttt atatttagaa
      481 gttttaaaaa atgatttaac tatacatact gaaaaaggaa tatatacttt taagaatagt
      541 atgaaagaaa tagaatcaaa tctagaagaa cataattttt ttagatgtca taaaagctac
      601 cttataaatt taatgaaggt aaatatgcta gatatagaaa ataatattgt atttataaat
      661 caaaattcaa taattgtaag tcgttataag ataaaattat tgagagaaaa gttaaatagt
      721 tgtttggtag atgtaataat ttgaggtaaa tttttgccct tatattctat tctaatagaa
      781 tatatctatt gtaaaatatg aaaaaattta taataaaaac taattatagt taaaaatata
      841 cctttcatca ataacagatt gaatatatta agattttatt ttacaattct attaacaatt
      901 ttattttaaa gatttaattt aaaatttaaa tatgtattat acataataaa ataatgttat
      961 attatattaa ttaataaaat attttatttc aattttatta agtatggagg tgtattgtgg
     1021 aaaatggtaa atttcaattt tttaaaggtg taagaaattg ttttaatatg atttatctac
     1081 atgataaaag atatttattt atctctatgt ttatggcaat ttttcagggg attgttccat
     1141 ctatttcttt gttagtaagt caaaatatca ttaataatat gcaaacattt tcgaaaagtg
     1201 taaaagaaat attagttttg ttaattatgt atttaatcat aaatataatt ccttcaattt
     1261 ttcaaagttt ttatggatat tatagaataa agtttaataa aaattttgaa aaacatattg
     1321 aaacaatgat gttagagaaa tctttaactt tgagtttaaa agattttgag gatgataata
     1381 cttatgacat gataaataga gctcaatctc aaaaaggatt taatattact atactatctg
     1441 aaaaccttat ttcaataata agagaatcag tatctacact ttctcttatt gttgtattat
     1501 cacaatttca actttggcta ataatagttg ttattgttat tcctgtattg aaatcattat
     1561 attccattaa attaggaaag gaacaatatg atgttagtgt aaacagaact tggaaagaaa
     1621 gaaaggcctg gtacatagat tatttgttgt caaaaggtta tgcttacaaa gagattatgg
     1681 tatttagaat tggttctaaa cttattaatc attataaaaa attaaaagag gatattatat
     1741 ctcaagatat gaatatagct aaaaagaatt ttattgctac gctattatgt acagttttag
     1801 attcaattgt atctgcagga attataggat ttataataat tcaaggtatt ttaaagaaga
     1861 ttttaatagg agatgcgact acatatatac aagcagttca atctataaag gataatgttg
     1921 aatcaatatt ttcgttattt agttcagtaa tacaagatct tttttataca gatttactgt
     1981 ttaaatttct agattataac tgtaaagaag actcaattga acatataaaa atatttgaaa
     2041 aaatagggga tataaataaa atagagttaa taaatatttc atataaatac aatcattcat
     2101 cagagtattc tttaaaaaat attaatttaa ctttaaataa aaatgatcct attgctatac
     2161 taggaaaaaa tggttcaggt aaaacgacac ttttaaaaat attattaggt ttttatgatg
     2221 attatgaagg tgacatcttg ataaatggaa aaaatttaaa ggatattgaa aaagatgaat
     2281 acattagaaa agtaagttgt atgtttcaag attatattaa atatgaggct acattaaaag
     2341 aaaatgtcgc catgggagat gtatataaga gtaacttgga agaaaaagtt aaaagtaaac
     2401 ttaaagaaac taaattgaaa ccaagtattt atgaggaaga tggattagaa actattttag
     2461 gaacctggtt tggtaagaag caactttcta tgggtgaatg gcaaaaagta gcaatatcta
     2521 gaactcttat gaaagatgct gatatgtaca tttttgatga accagattca tctttagatt
     2581 ctgaagcggg aaatgaactc ctttctttat ataaaaaaac atttgaaaat aagattggaa
     2641 tatttataac gcaccatatc caacatgcaa aaaagataac taacaatatt gtagttcttg
     2701 aaaatggaaa gttgttagaa agtggaagac atgatgaact tatggacaaa aagggtgttt
     2761 attttaattt attttgtaac tgcaaataaa tattaaaggg aggttaatta atgaatcaaa
     2821 aaccatttat acacacattt aaagctggaa aatcatattt tatttatgat gttaatacgg
     2881 ataagatttt aaaggtaaat gctgctgttt ataattatct aaataaaatt gagcataatt
     2941 tagaaaaaga aagtgactgg aacatagaaa tagaagacga aattaatacc ttgattaatt
     3001 atggatttct aaaaaataaa agggtaaata aaacaatgca ccctgaaact aagtatataa
     3061 aatatcatat agaaaataat ctatcctcta ttattttaca agtaacccaa aattgtaatt
     3121 tacgttgtga ctattgcatt tattctggtt catacagcaa cagagttcat acaaataaaa
     3181 gaatgaatat agatgtagca aaaagaagta ttgactattt gattaagaat tctagtcaat
     3241 taaatgaagt tagtgttggc ttttatggag gagaaccctt acttgagttt gatttgatta
     3301 agcagatagt agaatatgta aaagtagttg gagaaggaaa ggaaatatac tttaatctaa
     3361 ctacaaatgc aactttattt aatgaggaaa taatagaatt ctttgtaaaa aataatataa
     3421 caactatgat tagtttagat ggaggaaaag aaattcatga taaaagtaga aaatttgcaa
     3481 atacaggaga aggatctcat gatgttgtat taaaaaatgt acgttacata aaaaataaat
     3541 atccagaata ttataaaaag aatattacat ttaatacagt gataaattca gaaaatgatt
     3601 acatttctat agatgatttt atatctaaaa atgagacttt aaaagattca aactttttag
     3661 cttccactct taataataac tattctgata aagaaatagt ttcatcagat gaatatatat
     3721 taggtaagag ttatgataga ttcttgactt tactcaacaa attaaaattt ataaaagatg
     3781 agagtatgtc acctttatca agaatagaaa gagccttatt agatgatttt agatatgaga
     3841 aaaatattga aggtagatta gagttaccag atgtgtggca tcatggtgga ccatgtatac
     3901 caggggcttt tagaatattt gtaactacag atggagaatt ttttccatgt gagagagtaa
     3961 gtgaaagttc taaaatgggt atgattggaa atttagatag tggagtagat atagaaaagg
     4021 ctgaaaaact tttaaatata ggaaaattat atgaagagca atgttctgat tgttgggcct
     4081 atagttattg tgatatatgt atagctaaga ttgatgatac taaatgtaat gaaaatgaaa
     4141 taaaaccaca tgattgtgac agaattagac attctacaga aaataatatg aaagattact
     4201 gcgttttgaa atctctagga tatcaatatt aaattttcta atgaaaggaa agatgggatt
     4261 atggaaaaag tacttatata tccatttaat tataattttt ttactatttt aaatcattgc
     4321 aataaaattt cagatataga aattaattca ctggttagtc cttctggctg ggggttatgc
     4381 aataaggagt ataatgttaa taatattatt actaaagtta caaatgattt tcaaagtgaa
     4441 cttaaaaaga attctttggt atggtttgtt gattcaaaag aaaatctaga cttagaaaaa
     4501 tttataattc ctaaattaaa agtagctcta aaagaaggta aaaagatatt atatacacgt
     4561 gatgatctta ataaaatatc taggtatata tctcattatg aattcaaaaa gattaatgaa
     4621 tggaatttag aaaaatatga aataagagat atagagggta tatcacagat aaacacacca
     4681 ataatattta tttgtggtct ttatggaggg ttagatactt ttgatgtaaa tataaggata
     4741 ggagaagaac taagaaaaag ggggttttca atattacaat ttggtcctaa aaaagagagc
     4801 tatttattta aaatgattcc tataccagag tttatgtttg atgattcgat aagtagtaag
     4861 acaaagatta ttaattttaa ccattttata aaagataaag aggtagaggc aaagccagat
     4921 ttaataatta tagaagttcc aggagaatta ttccctttct ctagaaaaat ggttggtaat
     4981 tttggaatta gagcttttga aatttctaat gcagtaataa atgattgtgg tatattatgt
     5041 attccatcaa gtatatatga tagagaatat tgtgaagaac ttaaatattt tattaaagga
     5101 agacatggta taaatataga ttattttagt atagagaaaa aagttataga tacatatgag
     5161 acagaggtga agcaaaaatt ttcatatatg tcattagatg aaaacttttt tgttgaagat
     5221 atagaagatt atgaaaaaac attttttata catgataata aacaattact agaattagtg
     5281 gacaatatag tgaatcaatt aaaagagtat gctaaagtaa tatctattta gaattggagg
     5341 ttaattatga attacactga aaaggaatta ctactagaga atatattttt tgatgtgact
     5401 ggaattaatt ttaataaaaa taacaattta aaaaaagaat tatttttttc accgtcttta
     5461 catatacagc caagagaatt acttttagta ttttgcgagg taatagaaaa ctttaatata
     5521 aaaattccag aggaaaaact tttgaatagg caatttacga gttttgataa tgttctaaaa
     5581 ataatcaata tggtataggt taataaaggt ataaagtaag tgatcttata gaaaagggga
     5641 ggatatgaat gagttttgga aaaagaatag aaatgaataa tataggtgtt gagacaagag
     5701 gtgtttgtac tattatgtgt ccttatactt gtaagatgat ggcatcttca tcttgtaact
     5761 gcaagaataa tgattataat gcaagaggag gatcatataa tacatattat aataaattga
     5821 tacatggtca aagaactcct gatggaatgt aaatatttca gtaataagta tactattaaa
     5881 ttgatttagc atatttgatt aaatttatct ttcttacttt atttcctttt attataaaaa
     5941 tatgcagttg attataatta agagtgtgat tttataataa ctgcataaat agtatctgtt
     6001 atataaatca cctcttcaat tattatagtg gtaaatatag tgattagggg tgatttttac
     6061 aatttaaaag tataaattaa ttaaaagtta ttataataaa ttatacttat ttaaatagta
     6121 agaattaaaa gtaaagtttt taaatatatt tgtaaaaatg ta
//
LOCUS       DAMJYN010000148         6133 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.154, whole genome shotgun sequence.
ACCESSION   DAMJYN010000148 DAMJYN010000000
VERSION     DAMJYN010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6133)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6133)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6133
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.154"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            297..863
                     /locus_tag="PC466_003503"
     CDS             297..863
                     /locus_tag="PC466_003503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HDF2770854.1"
                     /translation="MSVSLQKGQRVSLVKDNNPVKNLVVGLGWDMNKLGKKNYDLDAF
                     AIALTNQDKMNVRGDLVYFGNLKHPSKAIIHTGDNLTGKGEGDDEQIIVNLEDIPEYV
                     HKIVFGVSIYKAKKRDQDFGQMNNSFIRLIDSNSKQELFKYNLQEDFSGKVTVLAGEI
                     YRRNEEWKFNALGIGQNEELRELINTYK"
     gene            903..1484
                     /locus_tag="PC466_003504"
     CDS             903..1484
                     /locus_tag="PC466_003504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HDF2770855.1"
                     /translation="MGITLAKGQKVSLTKSNPGLKKVIVGLGWDINKYDGGFDFDLDA
                     SAFLTGTDGKVTNDGDFIFYNNLKHASGAVEYMGDNRTGVGDGDDEQINVDLSKIPQN
                     IAKISFSVTINEAITRRQNFGQVENSYIRIYNEETNEELIKYELGEDFSIETAIVVAE
                     LYRHNGEWKFNALGSGFEDGLAGLCKNFGVNIG"
     gene            complement(1541..2458)
                     /locus_tag="PC466_003505"
     CDS             complement(1541..2458)
                     /locus_tag="PC466_003505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDF2770856.1"
                     /translation="MTIRSLEIFVKVAECGKMSEVARNMYITQSSVSQAISEIEKEYG
                     VKLFDRISKKLYLTEAGKKLLGYGRHLLAVNEEMNDCMKHCAKNIRIRVGATVTVGTC
                     VISPIMLELYKVNPLIEPEVFVEDTRLIAKKLLNSELDIAIVEGKIKHPDIVTKSIIN
                     DNLVLICSHKHEFYKRDSIKVSELSNQPLIMRELGSGTRAQLEKQLKELKIPMNIRWS
                     CYNSEAILRAVVDNFGIAVISELLIEDYLKKHLLWACDIEGINLHRTFDIAYHRSKFF
                     TENISAFFDISVEYGKKQARKKSRSVNSL"
     gene            2588..4219
                     /locus_tag="PC466_003506"
     CDS             2588..4219
                     /locus_tag="PC466_003506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HDF2770857.1"
                     /translation="MKVLIIGGVAAGTKTAAKIKREMGDNCSVTILNKGDDISYAGCG
                     LPYYVGKIIEDKSSLIVNTPESFSKLTGAEVRCGVEVTSIDRNAKQVTLKTLSTGEKE
                     NLSYDKLVIATGADPIKPPIPGIDLPGVFFMRTPNDAIKLRDSIENGIKRAVVIGGGF
                     IGLEIAENLSAMGIRVSVVDMAEHVMPGFDTDFAEYVENHMADKGIMIFTGDQVVGIE
                     GENKVEKLRTKNRAIKTDLVVMSVGIRPNTGFLKDTGLEFAPNNTIIADEYMLTNDKD
                     IYVVGDCAFVKNSLTNKPTWSPMGSSANHEGRICAQNISGKSKTYNGVLGTTVVKLPE
                     LNAGKTGLSKEIAEKEGYNVCSVTIATDDKAHYYPGASNFIIRMVAEKNTRKLLGVQV
                     MGPGAVDKIVDIAATAITLGADLYSLESMDLAYAPPFSTAIHPFVVAVNVLQNKLNGE
                     LDSVLLDEIEDFDSWTKLDVSKAPSIPSLRYIPVGEINGEIEGLAKDEKILLICAKGK
                     NSYMAQNRLRRFGYTNTKVLEGGILFYPNLKVMEE"
     gene            4222..5169
                     /locus_tag="PC466_003507"
     CDS             4222..5169
                     /locus_tag="PC466_003507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013378669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(4Fe-4S)-binding protein"
                     /protein_id="HDF2770858.1"
                     /translation="MSNVTAEQKKEVKGRGFLPSRDGEHFAARIITVNGVINASQAKK
                     IAEAAEKFGNGQLAFTTRLTVELPGVKFEDIEALSEFIASENLITGGTGSRVRPVVAC
                     KGTVCVHGLADTQALATEIHEEFYKNWYDVKLPHKFKIGVGGCPNNCIKPDLNDLGIV
                     GQRVPDYDSELCVGCKKCAVVEVCPVKAAKLTDKGKLEIDSNLCNNCGKCIESCNFDS
                     IEEKESGYKVYIGGKWGKSVRPGTQIDRLFSKEELMTLIEKAILLFREQGNTGERFGI
                     TIDRIGADKFIEMLLSDEVLERKEEILEALLHLTGGAVC"
     gene            complement(5454..5717)
                     /locus_tag="PC466_003508"
     CDS             complement(5454..5717)
                     /locus_tag="PC466_003508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1883 domain-containing protein"
                     /protein_id="HDF2770859.1"
                     /translation="MEYSYSKMNLKKGDIVEVNLEKQANVILLDHINYVKFKNQRNYD
                     YYGGFAKKNPCRMRVPNTGTWYLVVNQDGNSGIVNFSINTIQN"
     gene            complement(5816..6061)
                     /locus_tag="PC466_003509"
     CDS             complement(5816..6061)
                     /locus_tag="PC466_003509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770860.1"
                     /translation="MFIDEELEGYILTCKISEDFKNIPEYSDEEFYVTVYKDESSDSG
                     YYALLENKEERVVWDGEVVANNIFNNLWIVVNKVKTG"
BASE COUNT         2216 a          836 c          998 g         2083 t
ORIGIN      
        1 ttccaaatac gttctcattt agatagtgtg cttagaaatt ttagaattat tgagtctaac
       61 tttattactt actttacttt ataacaatca aatacaaatt taaatattat aaaactacaa
      121 aataatttaa atcatataat gtcaatatgt ttaaattata aaatattcat gtagttatat
      181 aataaataat ttataaatat agccaactta gcctaaatac gtatataata tagctaatat
      241 ggttcttata cttgatacca tcaataaaac taaaaatata aaaaggagaa cttaaaatga
      301 gtgttagttt acaaaaagga caaagagtta gcttagtaaa agataataat cctgtaaaaa
      361 atctagtagt aggcttagga tgggatatga ataaattggg taaaaaaaat tatgacctag
      421 atgcatttgc aatagcattg actaaccaag ataaaatgaa tgttagaggt gacttggttt
      481 attttggaaa tcttaaacac ccttctaaag ctattataca cactggagat aacttaactg
      541 gaaaaggtga aggtgatgat gaacaaataa ttgttaattt agaagacata cctgaatatg
      601 tacataaaat agtttttgga gtttctatat acaaagctaa aaaaagagac caagattttg
      661 gtcaaatgaa caactctttt ataagattaa ttgattcaaa ttccaagcaa gaattattta
      721 aatataatct tcaagaagac ttttctggta aagtaacagt tttggcagga gaaatttatc
      781 gtagaaatga agaatggaaa tttaatgctt taggaattgg tcaaaatgaa gagcttcgtg
      841 aattaattaa tacatataag taataattac aataaaaaat ttataatgag gagttggttt
      901 aaatgggtat aactttagca aaaggacaaa aagtaagttt aacaaaaagt aaccctggtc
      961 taaaaaaagt aatagtagga ctaggatggg atattaataa atatgatggt ggatttgatt
     1021 tcgatttaga tgcctctgca tttttaactg gaactgatgg aaaagtaacg aatgatggag
     1081 actttatatt ctataataat ttaaaacacg cttctggagc tgttgaatat atgggtgata
     1141 atagaacagg tgttggtgat ggtgatgatg aacaaataaa tgtagactta tctaaaatac
     1201 ctcaaaatat tgctaaaata tcatttagtg ttactataaa tgaagcaatt acaagaagac
     1261 aaaatttcgg acaagttgaa aattcatata taagaatata taatgaagaa actaacgagg
     1321 aacttattaa atatgaattg ggtgaagatt ttagcataga aacagcaata gtcgtggcag
     1381 aactatatag acataatgga gagtggaaat ttaatgcttt aggttctgga tttgaggatg
     1441 gacttgcagg attgtgtaaa aattttggcg ttaatatagg ctaatatatc taaataaaaa
     1501 taagagtata ttgatatact cttattttta tttagatata ttataaactg tttacacttc
     1561 tactcttctt tctcgcttgt tttttcccat attctactga aatatcaaaa aatgctgaaa
     1621 tattttctgt aaaaaacttg cttctatgat atgcaatatc gaatgttcta tgtaagttaa
     1681 taccttcaat atcacaagcc cacaaaagat gcttttttaa ataatcctca ataagtaatt
     1741 cggatataac tgcaatgcca aaattatcta caactgctct taatatagct tcagagttat
     1801 aacatgacca tctaatattc attgggattt ttaattcttt taattgcttt tctaattgtg
     1861 ctcttgtacc acttcctaat tcacgcataa ttaatggttg atttgaaagt tctgaaactt
     1921 ttatagagtc tcttttgtag aactcatgct tgtgtgaaca tataagtaca agattatcat
     1981 taataatgct ttttgtaaca atatctgggt gcttaatttt tccttctaca atcgcaatat
     2041 ctaattcact attaagtaat ttttttgcaa tcagtcttgt atcttctaca aatacttcag
     2101 gttctataag aggatttacc ttgtataatt ctaacattat cgggcttatt acacatgtac
     2161 caacagttac tgttgcccca actcttatac ggatattttt tgcacaatgc ttcatacaat
     2221 cattcatttc ttcatttaca gctaaaagat gcctcccata tccaagaagt tttttccctg
     2281 cctcagttaa atataatttt tttgaaattc tatcaaataa cttaacacca tactcttttt
     2341 ctatttctga aatagcttgg ctaactgatg actgggtaat atacatattt cttgctactt
     2401 cactcatttt accacattca gcaaccttaa caaagatttc aagactacga attgtcatat
     2461 tatcacaacc ttagcaaaca ttagtaaatg cttatgattt tattaatatt ttagtatttt
     2521 acaaatatat tgtcaagaag tataatttta ttatagagtt ataaagtaga ttggagtgtg
     2581 atatattgtg aaagtattaa ttataggtgg agttgctgct ggaacaaaaa ctgctgcaaa
     2641 aataaaacgt gaaatgggtg ataattgctc tgttacaata ctaaataaag gtgatgatat
     2701 ttcttatgca ggttgtggtc ttccatatta cgttggtaag ataattgaag ataaatcatc
     2761 tttaatcgta aatacacctg aaagtttttc taaactaaca ggagcagaag ttcgttgtgg
     2821 agttgaagtt acgtctattg atagaaatgc aaaacaagta actttgaaaa cgctttcaac
     2881 aggagaaaaa gaaaatctaa gctatgacaa acttgtaatt gctacagggg cagacccaat
     2941 aaaaccacca atacctggaa tagatttacc tggagtattc tttatgcgta ctccaaatga
     3001 tgctataaaa ctaagagatt ctattgaaaa cggtattaag agagctgttg ttattggtgg
     3061 aggtttcatt ggtcttgaaa ttgctgaaaa tctttctgca atgggtatac gtgtaagtgt
     3121 tgttgatatg gctgaacatg ttatgcctgg atttgatact gattttgctg aatacgttga
     3181 aaatcatatg gctgataaag gcataatgat ttttacaggt gaccaggttg taggtattga
     3241 aggtgaaaat aaagttgaaa aacttcgtac taaaaataga gctattaaaa cagatttagt
     3301 ggttatgtca gttggaatcc gtcctaacac aggttttcta aaagacacag gtttagaatt
     3361 tgcccctaat aatacaatta ttgcagatga atatatgctt acaaatgata aagatatata
     3421 cgtagttgga gactgtgctt ttgtaaaaaa ttctttaaca aataaaccta catggtcacc
     3481 tatggggtca tctgcaaatc atgagggtag aatttgcgca caaaatatat ctggaaaatc
     3541 taaaacttac aatggtgttc ttggaacgac agtagtaaaa ttacctgagc tcaatgcagg
     3601 aaaaacaggt ctaagtaaag aaatagctga aaaagaaggt tataatgttt gctctgtaac
     3661 catagctacc gatgataaag ctcattatta tccaggtgca tctaatttta ttataagaat
     3721 ggttgctgaa aaaaatacta gaaaattatt aggtgttcaa gttatgggac ctggagcggt
     3781 tgataaaata gtagatatcg ctgctactgc aataacttta ggcgctgacc tttattcatt
     3841 agaaagtatg gaccttgcat atgcaccacc tttttcaaca gctattcacc cttttgtagt
     3901 ggcagtaaat gttttacaaa ataaacttaa cggagaactt gatagtgttt tacttgacga
     3961 aattgaggat tttgacagtt ggactaaact tgatgtttca aaagctcctt ctattcctag
     4021 tttacgttat attcctgttg gtgaaattaa tggagaaatt gaaggtcttg ctaaggatga
     4081 aaaaattctt cttatatgtg ctaaaggtaa aaatagctat atggcgcaaa atcgcttaag
     4141 acgctttggc tatacaaata cgaaagttct tgaaggtgga atactatttt atccaaatct
     4201 taaggtaatg gaggagtaaa tatgagtaat gttacagcag aacaaaaaaa ggaagtaaaa
     4261 ggtagaggtt ttctaccaag cagggatgga gaacattttg cagcacgtat aataactgta
     4321 aatggtgtaa taaatgcatc acaagcaaaa aaaattgcag aagctgctga aaaattcgga
     4381 aacggtcagt tagcatttac tactagacta acagtagaat tacctggtgt aaaatttgaa
     4441 gatattgaag ctctaagtga atttattgct agcgaaaatc taataacagg tggaactgga
     4501 tcaagggttc gtcctgttgt ggcttgtaaa ggtactgttt gtgttcatgg tctagctgat
     4561 acacaggcac ttgctactga aatacacgaa gaattttaca aaaattggta tgatgtaaaa
     4621 ctacctcata agttcaaaat tggtgttggt ggatgcccta ataactgtat taaacctgac
     4681 ctaaacgatc ttggaattgt tggtcaacgt gtacctgact atgattcaga gctttgtgtt
     4741 ggttgtaaaa aatgtgctgt tgtagaggtc tgtcctgtta aagcagctaa attaacagat
     4801 aaaggtaaac ttgaaataga cagtaatcta tgtaataact gtggtaagtg tatagaaagt
     4861 tgtaattttg atagtattga agaaaaagaa tctggttata aagtctatat aggagggaaa
     4921 tggggaaaat cagttcgtcc tggaacacag attgatagat tattttcaaa agaggaactt
     4981 atgactttaa ttgaaaaagc aattctttta tttagagaac agggtaacac aggtgaacgt
     5041 tttggaataa ctatcgatag aattggtgct gataaattta tagaaatgct tttatcagat
     5101 gaagttttgg aaagaaaaga agagatacta gaggctcttt tacaccttac aggtggagct
     5161 gtatgctaac aataaatatt ttaattgtac agataaccta tggaaaaaat tttagttaag
     5221 aataattaaa attctatata tgatatatga taaatgaggc tatctcaaaa cacagatacg
     5281 cctctttttc attgttgaaa tgataaagta tatttgagtt tatacaaaaa agagtgtctc
     5341 gtgaattata aaattcattt tgaggcaccc acattatttt ataataattg cttattaatt
     5401 ttattttaac tatataaaaa gtacaaaaag taagaatatc caatattcta aaattaattt
     5461 tgaattgtat tgattgaaaa gtttactatt ccactatttc catcttgatt tactactaga
     5521 taccatgttc cagtattagg aactctcatt ctacatggat ttttctttgc aaatccacca
     5581 tagtaatcat aatttctttg atttttaaat ttcacataat ttatatggtc taacaatatt
     5641 acattggctt gtttctctaa atttacctct acaatatccc ctttttttaa gttcatctta
     5701 ctataactat attccattga attactcctc cagtatcgaa taatctttgt tatttactca
     5761 tctcaaatat gtaaaaattc atttaaaata ttacaaatac tatataatta gactattatc
     5821 cagttttaac cttatttact acaatccaaa ggttattaaa aatattattg gcaacaactt
     5881 ctccatccca tacaactctt tcttctttat tttctaataa agcatagtac ccagagtcag
     5941 aactttcatc tttatagact gtaacataaa actcttcatc actatattca ggtatatttt
     6001 taaagtcttc agatatttta catgttaata tatacccttc taattcttca tctataaaca
     6061 aagcaattcc tccaatctct atatttttac taattatacc atattatgtc ataaactttt
     6121 tatttcatta caa
//
LOCUS       DAMJYN010000149         6026 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.155, whole genome shotgun sequence.
ACCESSION   DAMJYN010000149 DAMJYN010000000
VERSION     DAMJYN010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6026)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6026)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6026
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.155"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(214..723)
                     /locus_tag="PC466_003510"
     CDS             complement(214..723)
                     /locus_tag="PC466_003510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjiG family protein"
                     /protein_id="HDF2770861.1"
                     /translation="MSQQNTGNAIVNSKPKKTAVEIFMGGAKKGFYIGVEQILPAMIM
                     GYVIVQFLQLTGLVDILGNIFGPVMGIFGLPGESVVVLIAAFFAKAAGAATAANLFAQ
                     GLITAPQATILIMPCMLMGTLVGHYARIVLVANASTKYRMLLLAVPIFDAIVGMLIVR
                     VLLTVMGLM"
     gene            complement(725..1372)
                     /locus_tag="PC466_003511"
     CDS             complement(725..1372)
                     /locus_tag="PC466_003511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770862.1"
                     /translation="MDVTAGDNKVTWKGYLSLFVLIVLFSGVFKDSQGFLKALDFANL
                     TGSFGTIADGVDFMGKGGTGAKDGFLFALTLIPTVCFAVGLIDVVESMGGMKAASKIF
                     NPLLRPLLGIPGIAGIAFVSSFTSSDVASIMTKELFESGEITDDERTIFVAYQYAGSA
                     VILNTINTQAPLLPIALLALGPIILIEIFCKILGANLVRLIIGVRNKKNKAKEAV"
     gene            complement(1386..2558)
                     /locus_tag="PC466_003512"
     CDS             complement(1386..2558)
                     /locus_tag="PC466_003512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HDF2770863.1"
                     /translation="MNTYLNEISKFVDENREEIVSLWKEIVNIESYTHCKESVNKLAE
                     RLKLEFEKEGLDCELVDVGENGNTLIGTLGSNIDKKPIIFSGHMDTVFETGTFGENPF
                     KIIEGKAYGPGVLDMKGGIIISLYVIKALNKIGYKERPIKIVFSGDEEIGHKDSTGAD
                     VILREAKGALCAFNMETGLVDNSLCIGRKGRIGCNIHVKGVETHAGNDFEGGRNAIEE
                     MANKILRIQKLTNLDVGTTVSVSVIKGGRVENSIPEDCSIKVDLRFEKVEEMENVKEQ
                     VREICKETYIEGTSTEVNFISEMMPFETTEDVMRFHTFVNEVSRENGFGELNAKRLGG
                     SSDASYLTIANVPTICSFGVRGEWNHTSREYAVVDSMFERVKLISTVILNLDKFEV"
     gene            2826..4202
                     /locus_tag="PC466_003513"
     CDS             2826..4202
                     /locus_tag="PC466_003513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770864.1"
                     /translation="MKYKIGFLTTSYFMSDKFKQALKELNDTCEITFIELKGENPFNN
                     LPNIYYEQVDNFDGFVCSGIVPYSELIINIKDIKVPLNFLKLDERDFYKYLFKLLNSQ
                     KDIDFTKSFMDFLREDNNYYDIYSLIDSNKCPYTIKDFNIPQPVYDFKKLNDKLLEIH
                     LDLLRDNKINLSFTRNYIISCELNKLGYDCIYMVPSTESILNTFKSLVNEITLQNLDK
                     NKSATCIVTVNSSEYINEDLIFKNDEIQNQIYNTILNSLSRHGFYGVQVKKNDMKIEI
                     HTTKEILNNMTNNYTDFFISEDLKEIKYSLNIGWGIGNTNIHAEQNARQANGKSASLN
                     GNCTFIVNDTNDTIGPLYSNKNSNNIEDSSIANKVASFIPLSNTNVSKIMCMINDRNS
                     NNVSAEILADYMNITLRSANRILSILYKAGIATIVNTKLDNQRGRPKKIYKVDFLSFL
                     NKMQKLNS"
     gene            complement(4453..5286)
                     /locus_tag="PC466_003514"
     CDS             complement(4453..5286)
                     /locus_tag="PC466_003514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF2770865.1"
                     /translation="MTIKEVEEKTGLTRSNIRFYENENLIKPLRNERNGYREYSDENV
                     EDIKKIAYLRTLGITIDDIRNIILQKVSLVEVVEKQEKVLETKISDLENAKTMCNKML
                     ESDELSYLNLKVEQYITELPEYWNKNKPVFKLDSVSFLYIWGGKITWGIITIACLLIA
                     ITVFPKLPPQIPIQWNNGVANYVDKKFIYAYPVICVVFRILLRPFIWRWLQIHAFYSD
                     TIADYLTNFMCFVALSIEIFSILFIYNIARHVTIIIFIDILVFIVLLIIGVYKLFKKY
                     N"
     gene            complement(5615..>6026)
                     /locus_tag="PC466_003515"
     CDS             complement(5615..>6026)
                     /locus_tag="PC466_003515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HDF2770866.1"
                     /translation="GIDYENYDIVFLGYWVDKGICDKNSKQVLENIHNKKIALFGTMG
                     ASKKGSYGASIIEKIESIIPKDNEILGSFICQGKIAEGLKAKYKEMLKLSPDNEHIRQ
                     QLNNHEESQSHPDEQEIYEASMFAKNMMIKASIV"
BASE COUNT         2102 a         1028 c          646 g         2250 t
ORIGIN      
        1 tttcattgtt gaaattatga aaatatactt gatttaatac caaaagagta tctcatgaac
       61 taaaaagttc attttgagat actctcttct tttttaatta atatacatat taattactat
      121 attagtttat tactatatat caattactat tcattaatta ctattcatca attcttatat
      181 atcatttata attaggttat aattttatgt tatttacatt aatcccataa cagtgagtaa
      241 aactcttact atcaacatcc ccactattgc atcaaatata ggaactgcca acagtaacat
      301 tctatactta gtactggcat ttgctacaag cactattctg gcataatgac caactagagt
      361 acccattaac atacatggca taattaatat ggttgcttgt ggtgcagtga ttagaccttg
      421 tgcaaataag tttgcagctg tagctgctcc tgctgcctta gcaaagaatg ctgctatcaa
      481 aactacaaca gattccccag gtagtccaaa aatacccatt actggaccaa aaatatttcc
      541 taaaatatca actaaaccag ttaattgtaa aaactgcact attacataac ccattatcat
      601 ggctggtaat atctgttcaa cacctatgta aaaacctttt tttgctcccc ccataaatat
      661 ctcaacagca gttttcttag gtttactatt tacaattgca tttccagtat tttgttgact
      721 catactacac agcctcctta gccttattct ttttatttct tacacctatg attaatctaa
      781 ctagattagc accaagtatt ttacagaata tctctataag gattattgga cctaatgcca
      841 ataatgctat tggtaaaagt ggagcttgag tatttattgt gttcagtata acagctgaac
      901 cagcatattg atatgctaca aatatagttc tttcatcatc tgttatttcc ccactttcaa
      961 ataattcttt cgtcattatt gaggctacat ctgaactagt aaatgaagat acaaatgcta
     1021 ttcctgctat tccaggtata ccaagcagag gtctaagtaa tggattaaat atctttgatg
     1081 ctgctttcat tcctcccata gattcaacta catctataag acctacagca aaacagacag
     1141 ttggaatcaa agtcagagca aataagaaac catcttttgc tcccgttcct cctttaccca
     1201 taaagtctac accatctgca atagtaccaa atgaacctgt cagattagca aaatctaatg
     1261 ctttaaggaa gccttgacta tctttaaata ctcctgaaaa taatactatc aatacaaata
     1321 aagataaata ccctttccat gttaccttat tatctccagc tgttacatcc atataaaatc
     1381 cccctttata cctcaaattt atctaagttt aaaataactg tagaaattaa tttcaccctc
     1441 tcaaacatag aatctactac tgcatattct cttgatgtgt ggttccattc tcctcttaca
     1501 ccaaatgaac agattgtagg aacgtttgca atagttaaat aacttgcatc tgaactacct
     1561 ccaagtctct tagcatttaa ttctccaaat ccattttctc ttgacacttc atttacaaat
     1621 gtatgaaatc tcataacatc ttctgtagtt tcaaatggca tcatttcact tataaaatta
     1681 acttctgtag aagttccttc tatgtaagtt tctttacata tctctctaac ttgttcttta
     1741 acattctcca tttcttctac tttttcaaat ctaaggtcta cttttatact acaatcttct
     1801 ggaatagaat tttccactct tccaccctta atcacactta cacttactgt agttccaaca
     1861 tctaaattag tcaatttttg tatgcgtagt atcttattag ccatttcttc tatagcattt
     1921 cttccacctt caaaatcatt acctgcatgt gtttctacac cttttacatg tatattacat
     1981 cctattcttc cttttctacc tatacataaa ctattatcta ctaatccagt ttccatatta
     2041 aaagcacaaa gagcaccttt tgcttccctc aatataacat ctgcaccagt tgaatcttta
     2101 tgacctatct cttcatctcc agaaaatact atttttattg gtctttcttt gtatcctatt
     2161 ttatttaaag ctttaataac gtataaagag attattatac cccccttcat atctaaaaca
     2221 cctgggccat atgcttttcc ttctattatt ttaaatggat tctctccaaa tgtacctgtt
     2281 tcaaagacag tatccatgtg tcctgaaaaa attatcggct ttttatctat attagaacca
     2341 agtgtaccta tcaatgtatt accattttcc ccaacatcta ctagttcaca atccaaacct
     2401 tctttttcaa attcaagctt taatctctca gctaacttgt ttacactttc tttacaatgt
     2461 gtataacttt ctatattaac aatctctttc cataatgaaa ctatttcttc tctattctca
     2521 tcaacaaact tagaaatttc atttaaatat gtattcataa tcttctcctt tattttcaaa
     2581 taaaatgtat ttctttccta aaatctaagt ttattttagg aaatcttaaa agactagtcc
     2641 ttaattacaa aatagcacaa ttattcttgc cagtcaacat atttttcagt cttttttata
     2701 ttttctgatt tttctttcaa ttatcctttt gtaaaataaa ttgacgcgtt ttatctacta
     2761 ttataaaatg aggttataaa ttgattgatt agttacaata ctctcgaaat tttaaaggag
     2821 gttttatgaa atataaaatt ggttttttga caacatctta ttttatgtca gataagttta
     2881 aacaagctct taaagaatta aatgatactt gtgaaattac atttattgag cttaaagggg
     2941 agaatccttt taataattta cctaatatat actatgagca agtagataat tttgatggat
     3001 ttgtatgcag tggtatagtt ccatatagtg aacttataat aaatataaaa gacataaaag
     3061 ttccattaaa ttttttaaag cttgatgaaa gagattttta taaatactta ttcaaattat
     3121 taaatagcca aaaagatatt gactttacaa aatcatttat ggatttttta agagaggaca
     3181 acaattatta tgatatatat tcattaatag actctaataa atgtccatat acaattaaag
     3241 attttaatat ccctcaacct gtatatgact ttaaaaaatt aaatgataaa ttattggaaa
     3301 tacatttaga cttattgcga gataataaga ttaacctttc ttttactaga aattacatca
     3361 ttagttgtga acttaataag cttggatatg attgtattta catggttcca tctacagaat
     3421 caatcctgaa tacatttaaa tctctggtga atgaaataac attacaaaac ttagacaaaa
     3481 ataaatctgc aacttgtata gttacagtaa atagttcaga gtacataaat gaagatttga
     3541 tatttaaaaa tgatgagata caaaatcaaa tatataacac tatattaaat tctctatcaa
     3601 gacatggatt ctatggagtt caggtcaaaa aaaatgatat gaaaatagag atacacacta
     3661 ctaaagaaat attaaacaat atgaccaata actatacaga tttttttatt tcagaagatt
     3721 taaaagaaat taaatatagc ttaaatatag gttggggcat tggaaataca aatattcatg
     3781 cagagcaaaa tgctcgtcag gctaatggta aatctgcttc tttgaatgga aactgtactt
     3841 ttatagtaaa tgatactaat gatacaatag gccctttata ttcaaataaa aattctaata
     3901 atattgaaga tagctcaata gccaataaag ttgcttcttt tatacctcta tctaatacaa
     3961 atgtatctaa aatcatgtgt atgattaatg atagaaattc aaataatgtg tcagcagaaa
     4021 tattagcaga ctatatgaac ataactctta gaagtgctaa tagaatattg agtatcttat
     4081 ataaagcagg aattgcaact attgtaaata caaaactcga taatcaaaga ggaaggccaa
     4141 aaaaaatata taaagttgat ttcttatctt ttctaaataa gatgcagaaa ttaaattctt
     4201 aatatttaat tttttaataa aagcaatgta ttttctctaa ttttaaagaa tcaaaatgtt
     4261 taaattttat tagaatatac aactttttac tttaaaatac ctaaaccttt tatcagtgaa
     4321 ataaaccata atatatcgta gcttattaga aaaacaaaat aatttcatat acaaataata
     4381 aaatagccac tacaatccat aatttgcagt ggctactttt tacactatca cttattactt
     4441 aatttttaaa aattaattgt attttttaaa taatttatac acacctatta tcagtaaaac
     4501 aataaataca agtatatcta taaaaataat tattgtaaca tgtctggcaa tattgtaaat
     4561 aaaaagtata gagaatattt ctatagacaa cgctacaaaa cacataaaat tcgttaaata
     4621 atctgcaata gtatcactat aaaaagcatg tatttgtaac catctccata taaatggacg
     4681 taaaaggatt ctgaatacaa cacaaatgac agggtaggca taaataaatt ttttatctac
     4741 ataattagct acaccattat tccattggat aggaatttga ggtggcaact ttggaaatac
     4801 tgttattgca atcaacaaac aagcaatagt aataattccc caggtaattt tccctcccca
     4861 tatatataag aaacttacag agtcaagttt aaaaacaggt ttgtttttat tccagtattc
     4921 tggcaactca gttatgtatt gctctacttt caaattcaaa taacttagct catcagattc
     4981 taacatttta ttacacatag tttttgcatt ttctaagtct gatattttag tttcgagaac
     5041 tttctcctgt ttctctacaa cttcaactaa agatactttc tgtaatataa tattacggat
     5101 atcatcaata gtaattccta gtgtacgtaa atatgcaatt tttttgatgt cctctacatt
     5161 ttcatctgaa tattctctat agccattacg ctcattacga aggggtttaa ttaaattctc
     5221 gttctcataa aaacgaatat tagagcgtgt caatcctgtt ttttcttcaa cttctttaat
     5281 tgtcatttta aacactacct ctctattcta ttaatttaca actataatat agtcttaaat
     5341 attttcactc tataaaattg tatatttagt atatcttaaa atcaagttaa ttatctttta
     5401 taaattttca tacaataata tctcctttca ataatatctc tttttctata tttaaaacta
     5461 tcttattttc tataaaataa tgtataaaca aggtttacag tcaagtattt ttattatttt
     5521 tttgatttca taaaaaaaag catagcaaat catttgctat acttttttac taaattattt
     5581 attctatatc ttatatgaac ttattgttta actactacac aatactagct ttaatcatca
     5641 tattttttgc aaacatactg gcttcatata tttcttgttc atctggatga ctttgagatt
     5701 cctcatggtt atttaattgt tggcgaatat gttcgttgtc aggagaaagt tttaacatct
     5761 ctttatattt tgctttcaat ccttctgcta tcttaccttg acatatgaat gaacctaata
     5821 tttcattatc ttttgggata attgattcta tcttttctat tatactagct ccataacttc
     5881 cttttttact tgctcccatt gttccaaata gtgctatctt tttattgtga atattttcaa
     5941 gcacttgttt tgaattttta tcacaaattc ccttgtccac ccaatagcct aagaatacta
     6001 tatcataatt ttcatagtca atacca
//
LOCUS       DAMJYN010000150         5997 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.156, whole genome shotgun sequence.
ACCESSION   DAMJYN010000150 DAMJYN010000000
VERSION     DAMJYN010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5997)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5997)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5997
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.156"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(457..1173)
                     /locus_tag="PC466_003516"
     CDS             complement(457..1173)
                     /locus_tag="PC466_003516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2770867.1"
                     /translation="MNQNILVVDDDREIVDAIEFYLRPDNFNVLKAYDGLEALDILIE
                     NDIKLIIMDVMMPNLDGLKTTLKIREKRNIPIILLSAKSEDMDKIIGLNMGADDYITK
                     PFNPLELTARVKSQLRRYINLGDFSNTNNSNDTNYILKSGGLELNTDTKIVSLDGEEI
                     KMTPLEYKILTLLMSRKGKIFSSREIYENVWNEDAYSCERTIAVHIRRIREKIEINPK
                     EPKYLKVVWGIGYKIEKLNY"
     gene            complement(1714..2514)
                     /locus_tag="PC466_003517"
     CDS             complement(1714..2514)
                     /locus_tag="PC466_003517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HDF2770868.1"
                     /translation="MTFKNKKFTINKYEILSIILVLCLILTGFSSYVNYSHKKFKDYV
                     VFYVQHQDDEVLWAGSAIVNAIKERGKNHVFVVLVSTGCGISVFDKYKKYENLTNIQK
                     SEYRNREFLASLNSLGVIRENIILLPETNTNGNTDFNYMEKIALTFEEKFKNVTHIAH
                     TYKLDDHLQHLKNGSVIQNLYNVGKIKDAKYFVKPKFADKITFNNKIVYKAHSTEDYE
                     KVKNACQQYKIVDELEYREGIGYKSDHKSFDKLLNNKDVPAILHTPNL"
     gene            complement(2829..3560)
                     /locus_tag="PC466_003518"
     CDS             complement(2829..3560)
                     /locus_tag="PC466_003518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770869.1"
                     /translation="MNIFDILRDYLLVQVDKYNLNMDMISIVSKSLSSKEAIGNTKRK
                     DFPIIVGKEIMLEADFKGAKGQAFTSTPSTFEGSLKDILSLDLHDNPHDRSLFIASLN
                     AVMKYLGKTDRTIHCKNNEPEVCAKKFPEFIKMEFGNPKVAIIGYQPAIIDNIKDFFE
                     TRVLDLNPEFVDTIQYNVKIEDGIRDYEDVISWADLVICTGSTLCNNSIINFLSLNKP
                     VYYYGTTIAGASNILGLKRLCFCSK"
     gene            complement(3547..4242)
                     /locus_tag="PC466_003519"
     CDS             complement(3547..4242)
                     /locus_tag="PC466_003519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF2770870.1"
                     /translation="MLKIKNLSLDLPNFKLQENSLNINNHEYFVLLGASGSGKTLFLE
                     TLAGRYPSAKGNVSYKENLISNLPPENRNIGFVYQNFELFPNMNVEDNIRFPLKLRKI
                     PIDEQILKANHLSKLMQIEDIKNRYPKNLSGGEKQRVAFARALIAEPDILLLDEPMSS
                     LDYITKKHISKILKDVYIKYKPTVIHVTHDISEAMFFAHKIGIMNNGKINHIFDLNEE
                     IKNKGESFFYEYI"
     gene            complement(4244..5035)
                     /locus_tag="PC466_003520"
     CDS             complement(4244..5035)
                     /locus_tag="PC466_003520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2770871.1"
                     /translation="MKNKFFTTLLTGFFAIVFFFIVSPLLMLIIKGISYVPICLKSVE
                     VQYAITLSIKTSLISTIVCLLLAIPVAYFLHITKLPFKKLIIQIINLPMSLPHLVSGI
                     ALLLLFGRMGIGDSIYKIFKLDFIFTKQGIVLAQVFVNLPLTIKILHTSLNESNEKMI
                     FVARTLGCNSWEAFRFIILPNLKTGIISATVMTWSRALGEFGAVAMIAGSTRMKTEII
                     PTSIYLNMSTGDIDIAIGIAVILIFISLTCLMLFEIFFNREVDKN"
     gene            complement(5045..5857)
                     /gene="modA"
                     /locus_tag="PC466_003521"
     CDS             complement(5045..5857)
                     /gene="modA"
                     /locus_tag="PC466_003521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter substrate-binding
                     protein"
                     /protein_id="HDF2770872.1"
                     /translation="MFKKLSVLALAMIISLSITACNSKENKANDESNTKVTTADDSKE
                     KETLFVYSGAGLKKPMDEIAKKFEKENNVKVEYSYAGSAQLIAQIETSHKGDVFIVGS
                     EPIYSKAFEKELVGEHKTVAHHTPAIVVPKGNPANIQKLEDLNKDGVKLILGDKESNA
                     IGKTTQKILEKNNLKSINDNVVSTAATVNEMIVQLTSSKADATIATKDSVFGNEDVEV
                     IEIAQDKNIDQLISAGIVNYSDKKDLANKFINYIESDEAKQIFKKYGFEPVK"
BASE COUNT         2092 a          843 c          727 g         2335 t
ORIGIN      
        1 atattttcat atattatata gactatagat ataattataa aattgtagat tattaaatta
       61 gtgttgtaaa acattttatt acttgtaaat gcatgaaacc ttaaggttaa tagtatcaaa
      121 gttaatataa gtgtaagttc tatttttacc ttagaaaaaa ggcttatgac attctctaag
      181 aatttgactt tagtctgttt atttttttta tacaatgtaa aacatagtat agtcaataaa
      241 aaacttgata atataatacc tatgcagaca aactctaatt ctacttttga caaatgtaca
      301 ggagtaccga aaaaataaaa ataagggaga gcaaactctt tataataaca attaatatta
      361 taagaaaagt tattattcaa atcataaact gcttcaaata atatagaaac taatagaaac
      421 agtaataata ataaaataaa ttttgcttta gaatcattaa taattaagtt tttcaatttt
      481 gtaaccaatg ccccacacca cctttaaata ttttggttct tttggattaa tttcaatttt
      541 ttctctaatt cttctaatat gaacagcaat agttctctca caactataag catcttcatt
      601 ccagacattt tcataaattt cacgggaaga gaaaatttta ccttttcgtg acataagaag
      661 tgtaagtatt ttatattcaa gtggtgtcat tttaatttcc tcaccatcta aagaaactat
      721 ttttgtatct gtatttagct ctaggccacc actttttaga atataattag tatcatttga
      781 gttatttgta ttactaaaat cacctaaatt tatatacctt ctaagttgag attttactcg
      841 agcagtaagt tctagtggat taaatggttt agttatatag tcatcagcac ccatattaag
      901 acctataatt ttgtccatat cttctgattt tgcagataag agaattattg gtatattcct
      961 tttttctctt attttaagtg tagttttaag cccatctaaa ttgggcatca ttacatccat
     1021 tattattaac ttaatatcat tttcgattag tatgtccaat gcttcaagtc catcatatgc
     1081 ctttaaaaca ttaaagttat caggtctcaa atagaactct atagcatcaa ctatctctct
     1141 atcatcatct acaaccaata tattttgatt caatttatta acccccttga aattttattt
     1201 ttaaccaatt tttattttat accaaaaaga ggtattagaa aacagtaagc ccgttcatta
     1261 tgaaataaaa actagtactt ttaatatatt gtcaatgcat atagtaaatt taaaagtata
     1321 gacgcccata ttaatctgaa ggtaaaagtt tatgaaaata tctagggtaa tctatcacac
     1381 tccttatgtt attttgggtt tattaatttt ttaggtttaa acatatatta acaaatataa
     1441 ataacaaatg agtttcataa ttattaagaa tttataacaa atatttattt taatgtagtt
     1501 taatataaat aggtagttta atgtagatat gtataaagta tttaataagg cttataggtt
     1561 ttaatgatga tatctttata tattttaaga gatgatgaaa ttagatatgg gtaatagttg
     1621 aatgagaaaa agtagtatag cacaaaaagt gctatatcac aaaatctcaa ataatttcct
     1681 tcttataact taaattaaaa gaataaatat ttcttataaa ttaggtgtat gaagtatagc
     1741 aggaacatct ttattattta ataacttatc aaatgattta tggtcagact tatagccaat
     1801 accttctcta tattctaatt catcaacaat tttgtattgt tgacaggcat ttttaacctt
     1861 ttcatagtct tcagtagaat gagctttata aactatctta ttattaaaag ttattttatc
     1921 agcaaattta ggttttacaa aatatttagc atcttttatt ttaccaacat tatataaatt
     1981 ttggataaca gaaccatttt ttaaatgttg taaatggtca tctaacttat aagtatgtgc
     2041 tatatgagtt acatttttaa atttttcttc aaatgtaaga gcaatttttt ccatgtaatt
     2101 gaagtcagta ttaccatttg tatttgtttc tggtaataat attatatttt cccttattac
     2161 accaaggcta ttaagagaag ctaaaaattc tctatttcta tattctgatt tttgtatatt
     2221 tgttaggttt tcatattttt tatatttatc aaagacggat ataccacatc cagtagatac
     2281 taaaactaca aatacatgat tttttcctct ttcttttata gcattaacaa tagcactccc
     2341 agcccacaac acttcatcat cttgatgctg aacatagaag acaacataat ctttaaattt
     2401 tttatgacta taattcacat agctactaaa accggttaaa atcaagcata aaactagaat
     2461 aatagataga atttcatatt tatttatagt aaatttttta ttcttaaatg tcatttaatc
     2521 atctcctgaa aagttgtctt agttatatta tcaaacaaag tactaaaaat tatttcttaa
     2581 atgctgaaaa atatagagta gattaatgga ataaaatttt ttttattagt ttaaaataaa
     2641 gaaaacattt atgtataaga ctaatcaaaa tattaataat tgataggaat tgagatttaa
     2701 agggattgta catttattcg ggattcattt taatagaatt ttactttagt acttagaata
     2761 aaagtaataa ctttttaaat ttaaagagta cacatatata tttgtgtact ccttgatgat
     2821 atgattgctt atttactaca aaaacagagt ctttttaaac ctaaaatatt tgatgcacca
     2881 gctatcgtag ttccataata gtaaactggt ttgttaagtg atagaaaatt tataattgag
     2941 ttattacata atgtacttcc tgtgcaaatc actaaatcag cccaagatat tacatcttca
     3001 taatctcgta taccatcttc aatcttaaca ttatattgaa tagtatccac aaattcagga
     3061 tttaaatcta atactcttgt ttcgaaaaag tccttaatat tatcaattat ggctggttga
     3121 tatcctataa ttgctacttt tggattacca aattccattt ttataaactc agggaatttt
     3181 tttgcacata cctctggctc gttattttta caatgaatgg ttctatccgt cttgcctaag
     3241 tatttcataa ctgcatttaa tgatgctata aaaagacttc tatcatgagg attgtcatgt
     3301 aaatctaatg ataatatgtc ttttaaagaa ccttcaaatg tagatggagt agaagtaaat
     3361 gcttgtcctt tagctccttt aaagtcagct tcaagcatta tttctttacc aactataatt
     3421 gggaaatctt tacgcttagt atttccaatt gcttcttttg aagatagaga tttggacaca
     3481 atacttatca tatccatatt taaattatat ttatcgactt gtactaatag ataatctctc
     3541 aaaatatcaa atatattcat agaaaaaaga ttctccttta ttttttattt cttcatttaa
     3601 atcaaaaata tgatttattt ttccattgtt cattattcct atcttatgag caaaaaacat
     3661 tgcttcagaa atatcatgag taacatgaat cactgttggt ttgtatttta tgtagacatc
     3721 cttcaaaatt ttgcttatat gtttttttgt aatataatcc aatgaactca taggttcatc
     3781 taaaagtaat atatcaggtt cagctattaa ggcacgtgca aaagcaactc gttgcttttc
     3841 gcctccactt aaatttttag gatacctatt ttttatatct tctatctgca ttaatttaga
     3901 caagtggtta gccttaagaa tctgttcatc tataggtatt tttcttaatt taagtggaaa
     3961 ccttatatta tcttcaacat tcatatttgg aaataattca aaattttgat atacaaatcc
     4021 tatatttcta ttttctggag gtaagtttga tattaaattt tctttgtatg atacatttcc
     4081 tttagcagat ggatatcttc ctgctaatgt ttctaggaat agagttttac ctgacccact
     4141 agctcctaat aaaacaaagt attcatgatt attaatattt aaactatttt cttgtaattt
     4201 aaaattaggt aaatcaagag ataaattttt tatttttaac atattaattc ttatcaacct
     4261 ctctattaaa aaatatctca aaaagcatca agcatgtaag tgagataaat atcaaaatta
     4321 cagctattcc gattgcaatg tctatatcac cagtagacat atttaaatat atagatgtag
     4381 gaataatttc agttttcata cgtgtagaac ctgctatcat agctactgca ccaaattcac
     4441 caagtgctct tgaccaagtc attacagttg cagatatgat tccagttttt agatttggaa
     4501 gaattataaa tctaaatgct tcccaactat tacatccaag ggtacgtgca acaaatatca
     4561 tcttttcatt actttcattt agtgaagtgt gaagtatttt aatagtaagt ggaagattta
     4621 caaatacttg tgctaaaact ataccttgct ttgtaaatat aaaatcaagc ttaaaaatct
     4681 tataaatgga atctccaatc cccattcttc caaacaaaag taaaagagca attcctgata
     4741 ctaagtgtgg aagagacata gggagattta ttatctgtat aatcagtttt ttaaatggta
     4801 atttagtaat atgtaaaaaa tatgctactg gaatagctaa taaaaggcat actatagtag
     4861 atattaaaga tgttttaata ctaagtgtta ttgcatactg tacttccacg gattttaagc
     4921 atataggaac ataacttatc cctttaatga ttaacataag aagtggtgat acaataaaaa
     4981 aaaagactat agcaaaaaat ccagtaagta gtgtagtaaa aaatttattt ttcaagttta
     5041 atcactactt aacaggttca aaaccatatt ttttaaatat ctgtttagct tcatctgact
     5101 ctatataatt tataaattta ttagctaaat cttttttatc actatagttt acgattcctg
     5161 ctgatatgag ttggtctata tttttatctt gggcaatttc tataacttct acatcttcat
     5221 tgccaaagac cgaatctttt gtggctattg tagcatcagc tttacttgat gttaactgta
     5281 caatcatttc atttacagtt gcagctgtag agacaacatt atcatttata gattttaaat
     5341 tatttttttc aagtattttt tgtgtagtct tacctatagc attagactct ttgtctccca
     5401 aaataagttt aactccatct ttatttaagt cttccaattt ttgaatatta gctggatttc
     5461 ctttaggtac aactattgca ggtgtatgat gtgcaaccgt tttatgttca cctacaagtt
     5521 ctttttcaaa ggcctttgaa taaattggtt cagaaccaac aataaatacg tctcctttgt
     5581 gacttgtctc aatttgagct attagctgtg cagaacctgc atagctatat tcaactttga
     5641 cattattttc tttctcaaat ttttttgcta tttcatccat tggtttcttt aaacctgccc
     5701 ctgaatagac aaaaagagtc tctttttctt ttgaatcatc agctgttgtc actttagtat
     5761 tagattcatc attagctttg ttttctttag aattacatgc agtaatactt aatgaaataa
     5821 tcatagctaa agctagtact gaaagttttt taaacataag atattccccc ttagtaaatt
     5881 agtgtaaatt cttttttagt atatcatact aagaaaacga tgtctaagtt tttgttatgt
     5941 tttataatgt tttgttatgt tttattatgt atagttaaga aaaaatctat ttataat
//
LOCUS       DAMJYN010000151         5980 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.157, whole genome shotgun sequence.
ACCESSION   DAMJYN010000151 DAMJYN010000000
VERSION     DAMJYN010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5980)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5980)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5980
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.157"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            <1..566
                     /locus_tag="PC466_003522"
     CDS             <1..566
                     /locus_tag="PC466_003522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDF2770873.1"
                     /translation="YKITSLYIFKNFKIGILLVFYFLFSQIIFGLIISDNQFDYKNFL
                     NYILLPIISLVYIYPFLCEEYGWRSFLQSILFDRFGKKIGIVMVGTCWSLWHLPLQFT
                     LYSPQTPIIGAIAHLIYGIGLSIFLGYVYMKTKNIWFCSIMHVLINSLGLIFNDSEII
                     INYHSIIQRLIFILLFYTPFLFTKEYK"
     gene            946..2472
                     /locus_tag="PC466_003523"
     CDS             946..2472
                     /locus_tag="PC466_003523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HDF2770874.1"
                     /translation="MNESYWFLNSSPKEYNKLGENIKTDCLIVGGGITGLTTAYLLAK
                     EGKKVVLVEADKIGYGTSGRNTGKVTCQHDIFYSKIEKKYGLDKAKSYYNANNEALNL
                     VEQIIEENNIKCDFKRETSFVFTEKEDTIKNIKDEYRTCKKIGINCEYHETIENIPLD
                     IKGAISFTNQGQFNPKKYIDGLAKAAVNLGLKIYENTPVVDLEKGKICRVKTREDNII
                     EAENVIISSHSPWYDGLNFYFAKEYAERAYLMVAVLENKLADGMFISIDDPSITFRQY
                     NNGSENLLIFGGGDHKVGQGGTEKEIFDDLEHYGKEVFKVKDFKGKWSAQDNMSFDNV
                     PYIGYINKREDNIYVATGFSKWGITNGTAAGIIIKDLIINNNSDYKDTFNPSRLGSYF
                     SKDFIKENANVAINYVSGKLKIGSGDMPKNNGEGKIVNIDGKRYGVYKDDNGDFYIVD
                     TTCTHLGCELNFNSEEKTWDCPCHGSRFDYKGNILEGPALKPLKLYGHGDNDVNPKLL
                     "
     gene            2500..3051
                     /locus_tag="PC466_003524"
     CDS             2500..3051
                     /locus_tag="PC466_003524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770875.1"
                     /translation="MNKLLKPITILLYIVYILSAVFFVANKEYGSLGLVAISLVGTFI
                     LSFINKQTERLLSKELYIMLALFIMFSSLLGTCFNFYDINYYDDFLHLWSGIISCIVA
                     FSIIKYFYTQREISKMSKVFLVIFLFMFSMGVASLWEIGEFLMDTFVGTTTQAGGLED
                     TMIDMVDALIGTIITIPYYSKKI"
     gene            3580..4623
                     /locus_tag="PC466_003525"
     CDS             3580..4623
                     /locus_tag="PC466_003525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770876.1"
                     /translation="MLKKWFGIVKKRQKSESVKEEGEVILKNEKILSEEKLIDEEGVV
                     VNIDNEILTKVEVVNDDNEIEEKIIEEDWLISENTIKLDDKEAIINDKNIELCKKEVQ
                     VESEKIGLNKFEGLDQNENYNLEKNVIEEKKVSECLTEEDLEYIKEIKIKRGKSIKAI
                     NLYTKEEWVFDTHIQCSKKLKVPLGYIRENLKYGYMDYFGDAINYLSEVLNIDEYCKG
                     EWSYLDNSKSPSEIFNILNNKIFSIRLSNEKRNEILTNDKIEALKMNYRFECIDEEYD
                     EYFKKYKSIIKRGGKKKVELVNKKGDILEIFKSLEECAIYLQKEKNEVIQMLKYGDTK
                     VGRNFIRYSLRSI"
     gene            4734..5876
                     /locus_tag="PC466_003526"
     CDS             4734..5876
                     /locus_tag="PC466_003526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HDF2770877.1"
                     /translation="MSEEKNPKENTLDEPKNSDNVNSKKDDVSDEKNTDNKVKKREIK
                     LNNKTLKAIVAIVAVGAICLGGGYVFGKEAGRKLPATSKHYNSSEVVATIGDKKITGE
                     MLRKRMEPLFYLNAKTTMTDDEIRSYESNMIETMITSDILSSEAAKEKISITNDQLDA
                     QYNNLMSSIESAMGMTKEEFLKQFDLTEKYIKDDMKKELVASKYLNEKSKVTDKEAEN
                     YYNKNKSNYLQVRASHILIKTVDDKGKQVSSSKKAELKKEAEEILKKAQAGEDFATLA
                     KKYSEDSSAESGGDLGFFGKGQMVESFEKAAFALKKGEVSNKLVESDYGYHIIKKTDE
                     KYQPFEEVKSDLVSSLTSEKQNLLIQNLKEKYNVKITDKYQMKAKE"
BASE COUNT         2478 a          500 c         1019 g         1983 t
ORIGIN      
        1 cttataaaat aacaagttta tatattttta aaaattttaa gataggtatt ttgctagttt
       61 tttacttttt attttctcaa attatttttg gattaataat aagtgataat caatttgatt
      121 ataagaattt cttgaattat attcttcttc ctataatatc attagtatat atttatcctt
      181 ttttatgtga agagtatggt tggagatctt ttttacaaag tattttattt gatagatttg
      241 gcaaaaaaat aggtattgta atggtaggca cttgttggag tttatggcac ttacctttac
      301 aatttacact atatagtcct caaactccaa taattggagc tatagcccat ttgatatatg
      361 gtattggact ttctatattt ttaggttatg tttatatgaa aactaagaac atatggtttt
      421 gctctataat gcatgttcta attaatagct taggattaat tttcaatgat tctgaaataa
      481 ttattaatta ccatagtatt atacaaagat tgatatttat actattattt tatactcctt
      541 ttctatttac aaaagaatat aagtaagaat tacaattaat ttatataaaa taaattttta
      601 agtaaatatt tttatagaga gattgttata ttacatatca gaaaaatatt aaacgaacta
      661 aatcaataaa aaagttggtg gctaacaatt tataattgtt agcacaatat aatcttatgt
      721 attgaaatct agaatatcct catttttact tagcataaat actattgatt aagaaaataa
      781 tatagaaatt ataaatatat ataagtttag tctggtgtat aaaacaagaa aactaagtga
      841 tttttcattt agctttttat taagcttatt ttttatacta tttataataa ataaactcca
      901 tgatgggaaa actattacta tttaatatgt aaaggagtat tttaaatgaa tgaatcatat
      961 tggtttttaa actcaagtcc aaaagaatat aacaaattag gtgaaaatat aaaaacagat
     1021 tgtcttatag taggtggtgg aataactgga ttgacaactg catatttatt agcaaaagaa
     1081 ggtaaaaaag tagtgcttgt tgaggctgat aaaataggat atggaacttc tggaaggaat
     1141 actggtaagg taacttgtca gcatgatata ttttactcta agatagagaa aaaatatgga
     1201 ttagataaag caaaatcata ttataatgca aataatgaag ctttaaattt agttgaacaa
     1261 ataatagaag aaaacaatat aaaatgtgat tttaaaaggg aaacttcttt tgtatttaca
     1321 gaaaaagagg atactataaa gaatattaaa gatgaatatc gtacatgtaa aaaaatagga
     1381 ataaattgtg agtatcatga aactatagaa aatattccat tagatataaa gggggctatt
     1441 agttttacta atcaaggtca atttaaccca aagaagtata ttgatggatt ggcaaaagca
     1501 gcagtaaatt tagggctaaa aatatatgaa aatacaccag tagtagatct tgaaaaagga
     1561 aaaatatgta gggttaaaac aagagaagat aatataatag aagctgagaa tgttataatt
     1621 tcatctcata gtccatggta tgatggattg aatttttatt ttgcaaaaga atatgcagag
     1681 cgtgcttatt taatggttgc agttttggaa aataaattag cagatggtat gtttataagt
     1741 atagatgacc catcaataac ttttagacaa tataataatg gaagtgaaaa tttactgatt
     1801 tttggaggag gagaccataa agttggccag ggaggaactg agaaagaaat atttgatgat
     1861 ttagagcatt atggtaaaga agtctttaag gtaaaagatt ttaaggggaa atggtctgct
     1921 caagataata tgagttttga caatgttcct tatattggtt atatcaacaa aagagaagac
     1981 aatatttatg tagctacagg attctctaaa tggggaatta ctaatggaac tgctgctgga
     2041 ataataataa aagatttgat aataaataat aattctgatt ataaagatac ttttaatcca
     2101 tccagattag gtagctactt ttcaaaagat tttataaagg aaaatgcaaa cgtagcaata
     2161 aattatgtaa gtggaaaatt aaaaataggt agtggagata tgcctaaaaa taatggagaa
     2221 ggaaagattg ttaatattga tggaaaaaga tatggtgtat ataaggatga taatggagat
     2281 ttttatattg tagacacgac atgtactcat ttaggatgtg aacttaattt taacagtgaa
     2341 gaaaaaacat gggactgtcc atgtcatggt tctagatttg actataaggg aaatatactt
     2401 gaaggaccag ctcttaagcc attaaaactt tatggacatg gtgataatga tgttaatcct
     2461 aagttattat aaaattattt ttaggaaggt aaagtgtata tgaataaact tttaaagcca
     2521 ataactatac tattgtatat agtttatatt ttatctgccg tattttttgt agcaaacaaa
     2581 gaatatggaa gtctaggtct agtagcaatt agtttagttg gtactttcat tttgagtttt
     2641 ataaataagc aaactgaaag attattgagt aaagaattat atataatgct tgctttattt
     2701 ataatgtttt catcattgtt aggtacttgt tttaattttt atgatataaa ttattatgat
     2761 gattttttgc atttatggtc aggtataata tcttgtattg tggctttttc tataattaaa
     2821 tacttttata cacaaagaga gataagtaaa atgagtaaag tgtttttagt tatattttta
     2881 tttatgttta gtatgggagt agcgagttta tgggaaatag gtgaattttt aatggatact
     2941 tttgttggga ctactacaca ggccgggggg ttagaagata ctatgattga tatggtagat
     3001 gctttaatag gcacaattat aactattcct tattatagta aaaaaatcta atatatagtt
     3061 ttaaattttt tatattaatt ataatggatt taattaatca tgttgagttt caaggtctat
     3121 atgattaatt aaatccattt ttgttattta taattattat tgaatgtatt tttacatata
     3181 agatataagg tgatagatag aaattgttgg attatgtaaa taattaatat ataataccat
     3241 tatgggcaat aaatacaaat caaatgataa tatagtctat ttatgtaaat gttatattgt
     3301 atcctaagta taatagtaag ttttttgata gtggtgtaga aagtaaaaat ctactagcct
     3361 aaattgatgt atggattagt ttaggaacag taattgcata tcttaagttt gatgtcatgt
     3421 tgggctacta gaaataggtc atctttttca cttgaatatc ttttctttaa acatgaggag
     3481 tatcatatca aaaacatatg aaaattaagt gatttataag aacagtaata ttttatatga
     3541 tagtatagaa tagtaataaa gtattaggag gaacattgag tgttaaaaaa gtggtttggt
     3601 attgtgaaaa aaagacaaaa aagtgagtca gtaaaagaag aaggtgaagt aatattaaaa
     3661 aacgaaaaaa tattatctga agaaaagttg atagatgaag aaggagttgt agttaatatt
     3721 gataatgaaa tattaactaa agtagaagta gtaaatgatg ataatgaaat agaagaaaaa
     3781 ataatagaag aagattggtt aattagtgaa aataccataa aattagatga taaagaagca
     3841 attattaatg ataaaaacat agaattatgt aaaaaagaag ttcaagttga aagtgaaaaa
     3901 ataggtttaa ataagtttga aggacttgac caaaatgaaa attataatct agaaaaaaat
     3961 gttattgaag aaaaaaaagt aagtgaatgt ttgacagaag aagatttaga gtacataaaa
     4021 gaaattaaaa taaaaagagg aaaaagtata aaagctataa acttgtatac taaagaagag
     4081 tgggtttttg acactcatat acagtgtagt aaaaaactca aagttccatt aggatacata
     4141 agagaaaatt taaaatatgg atatatggat tactttggag atgcaataaa ttatttaagt
     4201 gaagtattaa atatagatga atactgcaaa ggtgaatgga gctatctcga taatagcaaa
     4261 tctccatctg agatatttaa tattctaaac aataaaatat ttagtataag gctttctaat
     4321 gaaaaaagaa atgaaatttt gacaaatgat aaaattgaag cattaaaaat gaattataga
     4381 tttgaatgta ttgatgaaga atatgatgaa tattttaaaa aatataagtc tataatcaaa
     4441 aggggtggaa agaaaaaagt tgaattagta aataaaaaag gtgacatttt agaaatattt
     4501 aagtctttag aagaatgtgc catttatttg caaaaggaaa agaatgaagt tatacaaatg
     4561 ttaaaatatg gagatacaaa agtaggaaga aactttataa ggtatagttt gagaagtatt
     4621 taatttcatt ttaaattcat aagagtttca tttctgattc acacatttaa tattatttta
     4681 atgtaaaata ataaaggtga agtattgcac aattaaaatt aaggagggta ttaatgtctg
     4741 aagaaaaaaa tccaaaagaa aatacattag atgaacctaa aaattcagat aatgtaaatt
     4801 ctaaaaaaga tgatgtgtca gatgaaaaaa atactgataa caaagttaaa aaaagggaaa
     4861 taaagctaaa caacaaaaca cttaaagcta ttgtagcaat tgttgcagta ggagctatat
     4921 gtttaggtgg aggctatgtt tttggtaaag aagctggaag aaaattgcct gctacttcaa
     4981 aacactataa tagcagtgag gtagtagcta ctattgggga taaaaaaata acaggtgaaa
     5041 tgttaagaaa gagaatggag ccattatttt atttaaatgc aaaaactact atgactgatg
     5101 acgaaatacg ttcatatgaa tcaaatatga ttgaaactat gattacatct gatatattat
     5161 cctctgaagc agcaaaagag aaaataagta taactaatga ccaactagat gctcagtata
     5221 ataatttaat gagtagtata gaatcagcaa tgggaatgac taaagaagag tttttaaaac
     5281 agtttgattt gactgaaaaa tatataaaag atgatatgaa aaaagagcta gtagcatcaa
     5341 aatatttaaa tgaaaaatca aaagttactg ataaagaagc agagaactat tacaataaaa
     5401 acaagagcaa ttatttacaa gttagagctt cacatatttt aataaaaact gttgatgata
     5461 aaggtaagca agttagtagt agcaaaaaag ctgaacttaa gaaagaagct gaagaaatac
     5521 ttaaaaaagc ccaagctggg gaagattttg ctactctagc taaaaaatat tctgaagata
     5581 gtagtgcaga atcaggtgga gatttaggtt tctttggtaa aggtcagatg gtggaatctt
     5641 ttgaaaaagc agcctttgca ttgaagaagg gagaggtatc taacaaactt gtagaaagtg
     5701 attatggata tcatataatt aagaaaactg atgaaaaata tcaaccattt gaagaggtaa
     5761 aatcagattt agtaagcagt ttaacatcag aaaaacaaaa cctacttata caaaatttaa
     5821 aagaaaaata taatgttaaa attacagata aatatcaaat gaaagctaaa gaatagataa
     5881 agtcaattta ttaaaaaaaa gaaaaattaa ctgtatggat aaaagctatt tttactctca
     5941 atatagagag tctaaagtag cttttattat tttgtaataa
//
LOCUS       DAMJYN010000152         5974 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.158, whole genome shotgun sequence.
ACCESSION   DAMJYN010000152 DAMJYN010000000
VERSION     DAMJYN010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5974)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5974)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5974
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.158"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            111..398
                     /locus_tag="PC466_003527"
     CDS             111..398
                     /locus_tag="PC466_003527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770878.1"
                     /translation="MKKILYALYSFIVIIANFRLKEKNYNFILLAIFFILLLIQNGVL
                     KTGYQNRATFYQDNYFNGEDKNDKIKFITIKIFIFLSLPLCFNILFNYLTS"
     gene            complement(936..1487)
                     /locus_tag="PC466_003528"
     CDS             complement(936..1487)
                     /locus_tag="PC466_003528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2770879.1"
                     /translation="MSINTVIAKNLNRLRNERNLSLGQLAELSGVSKVMLSQIEKGDS
                     NPTVNTIWKIASGLNVPYTAILEQPQNETFIVSKTDIDVQVSENKDYRLYCYYPNTPT
                     RNFELFQMELEEGHSYTSVGHSEKSQEYIMIIEGQLKLEVNDSIYQLRENDSICFSAE
                     SIHTYHNQGEKTLKAVIINYYPV"
     gene            1678..2640
                     /locus_tag="PC466_003529"
     CDS             1678..2640
                     /locus_tag="PC466_003529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase family protein"
                     /protein_id="HDF2770880.1"
                     /translation="MRVLNNVTEAIGNTHMLHLSKIADEFGVQGNIYAKMEYLNPGFS
                     KKDRVALQMITEAENAGLLVPGQAVVELTSGNTGTGLAIACACKGYKFIACMSKGNSM
                     ERARMMKALGAEVVLVDQMPNSVHGQVSGEDLALVEIEAQKIAKERNAFRADQFNLEA
                     CNHAHEKYTAEEMWEQLDGNIDVFVDFLGSGSTFAGCSKTLKKHNSSIKCYVVEPETA
                     AIYSGKEITDQGHKIQGGGYSMDLPLVDKKLIDGYIQVTDEEATDVARKLAKLEGVFA
                     GFSSGANVCAAIKLLKSSEKGKNIVLTLNDSGLKYLSTDLYEEL"
     gene            2935..4779
                     /locus_tag="PC466_003530"
     CDS             2935..4779
                     /locus_tag="PC466_003530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HDF2770881.1"
                     /translation="MQKRILRNFIFTGKNILSKLVFIIKYNFSTLILFELFHKGLALF
                     FIWPSIRYIFDILIKSLHIVYLNMDNFIKVLTNPMSIVLIILSVIILAFYAFFEFTSV
                     IICFNKSIKYEKIGLFELFKISFKNSIKLLYPKNILLFIFVILIIPLVNTVLISGFIG
                     KIQIPEYILDYIKSDIILNIIYMIFLLIIYISVIRWIFSIHEITLNTENFKRARKESV
                     NLIKRKIIRTIIYSLILSLVVAIIGYAIYHSGIIFIGIWTKYCTDMEFLKNVFINRCI
                     AFEEYFRLILSIFIFILDIGFISATYYQYKGVNISKNNIKKEKKSISKIVFNLVLILL
                     ISYIESVAFSSHINGMFNTSFSFYTTAIAHRAGAEMAPENTLAAIEEASNAKADYAEI
                     DVQETKDGELIVLHDSNFKRTTGVDKNVWDVNYNEVKTYDAGSFYYYGKGYYDEKFVG
                     EKIPTLKEMIKYSKGKVKLLIEIKLNGHEKGDIVKKVVQLIKENNFENQCIVASMDKT
                     ILQKVKKLDENLLTCYFMAIAYGDFSKLNYVDIYGIESTFVNKTVVEKIHKMNKKIFV
                     WTVNSDSLIEKMLDLNVDSIITDNPYLIESAIYWKKNGFISQVSDYLF"
     gene            5101..5685
                     /locus_tag="PC466_003531"
     CDS             5101..5685
                     /locus_tag="PC466_003531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HDF2770882.1"
                     /translation="MTEREKMLAGELYDCGDIELLTQWHKAKDLVRDYNQTDSSDLEK
                     KEKILNELLGGKDKNLWITAPYYVDYGNNIYFGNNCEVNMNCTFLDDNKIIIGDNALI
                     APNVQIYTAFHPTNAGDRFGNVKEDGSFEFCKTQTAPVTIGDNVWIGGGAIIMPGVTI
                     GDNVVIGAGSIVTKDIPSNMIAYGNPCRIIRENK"
BASE COUNT         2336 a          591 c          917 g         2130 t
ORIGIN      
        1 taaaaaatat ttaatgctac tacaatagga actagaactg cacttaataa atatacagaa
       61 attagatttg gctcaatata aaatacaaat atagaattta ggtgtttttt atgaaaaaaa
      121 ttttatatgc tttatatagt ttcattgtta ttatagctaa ttttagatta aaagaaaaaa
      181 attataactt tattttatta gcaatctttt ttatactgct gttaattcaa aatggagttt
      241 taaaaacagg ttatcaaaat agagctacat tttatcaaga taattatttt aatggagagg
      301 ataaaaatga taagataaaa tttataacta taaagatttt tatatttttg tcattaccat
      361 tatgttttaa tatactattc aattatttaa cttcttaaat tatatttaga tataggagtg
      421 ttatgataaa agtaagatta tgtgttgttt atattaaata taaagtgcat atagtgataa
      481 aacaaaagtt tcatataaat gaagaaaaaa tataaaataa tttatttaac tacttaaaaa
      541 taaactaaaa gggataataa aatagctttt aggttatggt aataaaggta tttaaaaaga
      601 gtgcataagc actccaattg tgagaaatac atacacaaat cattattaca acaatgaaaa
      661 atgtacatat aagagacgtt ttgtatttgt tttaagtgat aatattttaa tactaactaa
      721 ataattatca caataataaa aaagaaaaag gagtattttg tactccattt gtcaaaaata
      781 taaaactttt atataagctt attataacat aattgataaa agtgtaaagc tatataatga
      841 atttataaag aaaaataaaa taaaaaagat aaatcctaat caaaggattt atctttttgt
      901 atagaaaata attattctat tattaaatgg catggctaaa ctggataata atttattatt
      961 actgctttca atgttttttc tccttgatta tggtatgtat gaattgattc agctgaaaaa
     1021 caaatagagt cattttctct aagttgataa atagagtcat ttacttctaa ttttaattga
     1081 ccttctataa tcataatata ttcctgtgat ttttcagaat gaccaacaga tgtataacta
     1141 tgaccttctt ctaattccat ttgaaataat tcgaagtttc tagttggtgt attgggataa
     1201 taacaataaa gacgataatc tttattttct gaaacttgta catctatatc agtttttgat
     1261 acaataaaag tttcattttg aggttgttcc agtattgcag tatatggaac atttagtcca
     1321 cttgcaattt tccaaattgt gtttactgtt gggtttgagt ctcccttttc aatttgcgaa
     1381 agcattactt tacttacgcc agataattca gcaagttgac ctagacttaa gttacgttca
     1441 ttacgtaatc tatttaaatt tttagcaata acagtattaa tactcatagt aactccttaa
     1501 aatgtaaatt attgacaaat ataatttacg aatgtataat ttatttaaca ttatttataa
     1561 tttacaaatg tataatataa tgaacgttaa atacactgta catccgtaat ataaattata
     1621 ctgcataaag agttgttttt caacggatga tagttgagag attaaggggg aattgtaatg
     1681 cgtgtactta ataatgttac agaggctata ggcaatactc atatgttaca tttatccaaa
     1741 atagcagatg aatttggagt tcaaggtaat atttatgcaa agatggaata cttaaatccg
     1801 ggatttagta aaaaggaccg tgtagcatta caaatgatta ccgaagcaga aaatgcaggt
     1861 ttattagttc caggtcaagc agttgtggaa ttaacaagtg gtaatactgg aacaggacta
     1921 gcaatagctt gtgcatgtaa aggatataaa tttatagcgt gtatgtcaaa aggaaattct
     1981 atggaaagag caagaatgat gaaagcttta ggtgctgaag tagttcttgt agaccaaatg
     2041 cctaattcag ttcacggaca ggtatctggt gaagatttgg cacttgtaga aattgaggct
     2101 caaaaaatag caaaagaaag aaatgcattt agagcagacc aatttaattt agaagcttgt
     2161 aatcatgcac atgaaaagta tacagcagaa gaaatgtggg aacaattgga tggaaatatt
     2221 gatgtatttg tagattttct tggaagtggt agtacttttg caggatgttc aaaaacactt
     2281 aaaaaacata attcttctat caaatgttat gttgttgaac ctgaaacagc agcaatttat
     2341 tcaggtaaag aaataactga ccaagggcat aaaatacaag gtggaggata ttctatggat
     2401 ttgccattag tagacaagaa acttattgat ggttatattc aagttacaga cgaggaggca
     2461 actgatgtag caagaaaatt agctaaatta gaaggtgtat ttgcaggatt ttcttcaggg
     2521 gcaaatgtgt gtgcagcaat taagttgtta aagagcagtg aaaaaggaaa aaatatagtt
     2581 ttaactctta atgatagtgg tttaaaatat ttaagtactg atttatatga agaattgtaa
     2641 taatagcaca atagttatgc aatgtttttt aaattaagta tatagattta aattataaaa
     2701 agtatctcaa tgtgattttt gaaagttata aaagagatac ttttttattt tgtaaatatg
     2761 gagtatccta cttataagta ttaagctata tagatattga tgattagcta tgcaataaaa
     2821 aagagtatgt gtttttgcat ttatacatca taacttggaa taatacatat taatgttcta
     2881 aatgtattta aaacatatga taaaattaga acaaacagat acaaggagat aaacatgcaa
     2941 aagagaattt taagaaattt tatatttacg ggtaaaaata ttttaagtaa acttgttttt
     3001 ataataaaat ataattttag tacattaatt ttatttgaat tatttcataa aggattagcc
     3061 ttatttttta tatggccatc tattagatat atatttgata ttttaataaa aagtttacat
     3121 atagtctacc taaatatgga taattttata aaagttttga ccaatcccat gtcaatagtt
     3181 ctgataatac tatcagttat aatactagct ttttatgcat tttttgaatt tacctctgta
     3241 attatttgtt ttaataaatc gataaaatat gaaaaaatag ggttatttga actctttaaa
     3301 atatcattta agaactctat aaaattgtta tatcctaaaa atatactatt atttatattt
     3361 gtgatattaa taattccatt agtaaataca gttttaattt cagggtttat aggaaaaata
     3421 caaataccag agtacatatt agattatata aagtctgata taattttaaa tataatctat
     3481 atgatttttc ttttaataat ctatatttcg gttattagat ggatttttag cattcatgag
     3541 ataactttaa atacagaaaa ttttaaaaga gcaagaaaag aaagtgttaa tcttataaag
     3601 agaaagatta taagaacaat tatttattca ttaatattat ctttagtagt agctattatt
     3661 ggatatgcga tttatcatag tggaattata tttataggca tatggactaa atattgtact
     3721 gatatggaat ttttgaagaa tgtatttata aatagatgta ttgcatttga agaatatttt
     3781 agattgattt tatcaatatt catttttata ttggacattg gatttatctc agcaacttat
     3841 tatcaatata aaggagtaaa tatttctaaa aataatatta aaaaagagaa aaaatctata
     3901 tcaaaaattg tttttaattt agtattaata ttattgattt cttatataga gtcagttgca
     3961 ttttcttcac atataaatgg catgtttaat acgtcatttt cattttatac aacagcaatt
     4021 gctcatagag caggagctga aatggctcca gagaatactt tggcagcaat agaagaagct
     4081 tcaaatgcta aagctgatta tgcagaaata gatgttcaag aaactaaaga tggagaactt
     4141 attgtacttc atgattcaaa ctttaagaga actacaggag tagataaaaa tgtttgggat
     4201 gtaaattata atgaagtaaa gacatatgat gcgggaagct tttattatta tggaaaaggt
     4261 tattatgatg aaaagtttgt tggggaaaag ataccaacac tcaaagaaat gataaaatat
     4321 tctaaaggta aggtgaaatt attaatagaa ataaaactta atggacatga aaagggagac
     4381 atagtaaaaa aagttgttca gttaattaaa gaaaataatt ttgaaaatca atgtatagtt
     4441 gcatctatgg ataaaactat attacaaaaa gtaaaaaaac tggatgagaa tttactgaca
     4501 tgctatttta tggcaattgc atatggtgat ttttcaaagt taaattatgt tgatatatat
     4561 ggaattgaat caacttttgt taataaaaca gtagtagaaa agattcataa aatgaacaaa
     4621 aaaatcttcg tttggactgt taatagtgac agtttaattg agaaaatgct tgacctaaat
     4681 gtagatagta ttattacaga taatccatac cttatagaga gtgcaattta ttggaagaaa
     4741 aatggattta ttagtcaagt gtcagattat ttattttaaa tattctataa ttgtattatc
     4801 cagtaaaaga gatattatta aaatcaataa tatctctttt taacataaat aaggttgtta
     4861 aattaaggtt attcttataa aaattgtgct tatcagctat aaacaaggaa taaaagtgaa
     4921 aaaattgctc tgagattatt acagttaaaa gagttttaag atgacagaga gatagattgt
     4981 caactgtata tttaataaat cttgttattt attaaatttt atataagtaa aatatataaa
     5041 ttaataaatc ttatgctaga atatatatga aaaacaatat aaatttggag gattaaaaac
     5101 atgacagagc gagaaaaaat gttggcagga gaactttacg attgtggtga tattgagttg
     5161 ttaactcaat ggcataaagc aaaagaccta gtaagagatt ataaccaaac agattcctcg
     5221 gatttggaaa aaaaagaaaa aatattaaat gaattacttg gtggtaagga taaaaactta
     5281 tggattactg caccgtatta tgtagattat ggaaataata tttattttgg aaataattgt
     5341 gaagtcaata tgaattgtac gtttttagat gataataaaa ttatcattgg ggataatgca
     5401 ctaatcgcac caaacgtaca aatatatact gcatttcatc caactaatgc tggtgataga
     5461 tttggtaatg tcaaagaaga tggttcattt gaattttgta aaactcaaac agctccagtt
     5521 actattggag ataatgtttg gattggcggg ggtgctatta tcatgccagg tgttactatt
     5581 ggagataatg tagttatagg tgcaggaagt attgttacaa aagatattcc aagtaatatg
     5641 attgcatacg gaaatccatg ccgtattatt cgagaaaaca aataaagtta aattttcttg
     5701 caaaatctca aaaaacacct ttcttacttt atacataggg tattttccaa tactttcaca
     5761 tccatattca tttgttaaat ttttgtggaa tgtagttttt atcacttcta tcttacattt
     5821 ccaccatttt ttataaaagt cattccttta tagatttatt tataatagta tatattctat
     5881 ttgatgtttg aataagcact tatttttaag taaaatacta acttttaggt tagtattttg
     5941 ctatagtatg atgattaagt aagaataaaa tact
//
LOCUS       DAMJYN010000153         5957 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.159, whole genome shotgun sequence.
ACCESSION   DAMJYN010000153 DAMJYN010000000
VERSION     DAMJYN010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5957)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5957)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5957
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.159"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            179..1543
                     /locus_tag="PC466_003532"
     CDS             179..1543
                     /locus_tag="PC466_003532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase"
                     /protein_id="HDF2770883.1"
                     /translation="MDIKELVKMQRKYYNTGKTRDISFRIEQLKKLKLVVSQNEEKIL
                     LALKKDLNKSNFEGFMTEVGMFYSELNFAIKNIRKWSKIKRVKSSMVNFPSISKVVPQ
                     PYGVTLIMSPWNYPFQLALIPLVWSLAAGNCVILKPSEYSVSTSSVVKDIVENTFSKE
                     YVAVVQGSQEESEKLLLERFDYIFFTGSTNVGKIIMKSASEHLTPITLELGGKSPCII
                     LKDANIDLTAKRLTWGKLINAGQTCVAPDYVLVHEDRKNELIEKIKYYTNKYFGDNPC
                     NNEQFPKIINQRHFNRILSLIDKDKIVYGGNYNKETLKIEPTIVDNVNWDDNIMKEEI
                     FGPIFPILTYKDLDEVIQKIIQMPNPLALYIFTKNKYLENKLLEMIPAGGCCINDTVT
                     HIATNYLPFGGIGESGMGSYHGKAGFDTFTHYKSVLKKLNLDVPIRYAPYDNKLIKVL
                     KKIM"
     gene            1682..2848
                     /locus_tag="PC466_003533"
     CDS             1682..2848
                     /locus_tag="PC466_003533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HDF2770884.1"
                     /translation="MKINWNTKYTTIAIYTFIIAASSIIFYLVSSQIDVFSNNLDAIF
                     TTLQPFIIGFAIAYLLNFILKFYEDRIFIKSEKLKKLKQSSKRGLGLLLTYATATLIL
                     YLFMHFVLPQVIESIVGLANDIPMYVNNATKLIDKLMTDLNLDEQYFNLAVDKWNEFV
                     TYIIKFVTDLIPILGSMLKNVASSIWNIVLGLIVSVYLLIDKEKFYGLSKKITYAVFT
                     EKQAARILELTHRSNYTFGRFLGGKILDSFIIGILTFVILTLVKMPYTLLISVIIGIT
                     NIIPFFGPLFGAIPSTLIVMFVSPIKAFWLLLIILIIQQIDGNIIGPKILGDSIGISA
                     FWILFSLLVAGKLLGFIGMVIGVPMFAVIYSIIKDIVESKLDKKGLPTDTSDYM"
     gene            2965..3747
                     /locus_tag="PC466_003534"
     CDS             2965..3747
                     /locus_tag="PC466_003534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HDF2770885.1"
                     /translation="MAFIECKFKSKYTGGETDIIVILPVANGKELFSGKEIYDFEGKF
                     KTLYLFHGLEDDQSSWIRYTNVEHYAKNKNIALVIPRVETSFYTDMAYGHQYFTFVSE
                     ELPKFVRAIFPLSDKREDNFVAGMSMGGYGALKLALSKPKEFSAVASFSGSPDMIHEL
                     ENQQIETNADILFHDFGRPEDARNSENDLLYILKNLKERNEDIPKIYQFCGDRDFLYK
                     NNQMFKKYAESLGVDVEYEECVGGHEWRLWNLWIKKFIDIIG"
     gene            complement(3866..4519)
                     /locus_tag="PC466_003535"
     CDS             complement(3866..4519)
                     /locus_tag="PC466_003535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2770886.1"
                     /translation="MSKSEKGKETKASIISAARELFFEQGYHKTTTRQIAERANINLG
                     LISYYFSSKSEIGAIIYEDIRNEMQSLIYNYHEEGTMMMFFLAMNADLCFLLKNEAYR
                     NFYLDIAYEEAILSYQRSVTEMVMKRYVNDKESIEHDELILSCIGILAMKPEIIRVYT
                     SHKYDISSQAVIKHFTKQFLINLGHSTDLCEEILEELSKYYIDIVDNFTPIITRVRT"
     gene            complement(4543..5907)
                     /locus_tag="PC466_003536"
     CDS             complement(4543..5907)
                     /locus_tag="PC466_003536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter family protein"
                     /protein_id="HDF2770887.1"
                     /translation="MLLLIVTCAIYIWIGFYFSKKVKTASDFLIAGRNLPLPILAATI
                     AATSFGGGCLVGGVQWGAERGLWVGMYSTIGAALACFINAFFAGKLRSLSCDITPADY
                     IETRYGHSVFLRAYQSLVTPISILAIMGSQLISFGSVSTAFGIPYDIAVIIGVIVIII
                     YTYTSGMWGVAVSAFIQLAICIVFLPIVAYISLKLVGDNPLLMLQSMVKEPFFPGNKS
                     ISDFMYTVLPLVLGSIFSYESFLRYQCADNAKNAVKSSVIAGFILLFLAFPIGIIGAI
                     GGSLFPNISSVQVLPQMISTTLPPLISVLFLAAILAAIMSTADSLMTSMSAIISRDIY
                     NKLLHPNIEFNDLKNTLKYSQIASALTAIIGAIIALKFDSLLELLFWPAPLCTGVIFA
                     PFVIGLCWKGATKKGAIYAVIVSVILALLNMIGILTVFDRILVPIIGGSITIFIVSKF
                     SKKD"
BASE COUNT         2240 a          752 c          905 g         2060 t
ORIGIN      
        1 ttattttaaa ataaattatt ttataagctt acttatactt aataaggggc tttttttatt
       61 ggaagattta tgttatattg agatgaattt attatgatat aaaaaataat gttaggataa
      121 atttaaatct ttttctaaaa atgtattaat ataattctta aagaaaggat ttttaacaat
      181 ggatataaaa gagttagtta aaatgcaaag aaaatattat aatacaggta aaacaagaga
      241 tatatcgttt cgtatagaac agttgaagaa acttaagtta gttgtatcac aaaatgaaga
      301 aaaaatactt ttagcactaa agaaagattt aaataaatcg aattttgaag gttttatgac
      361 agaggtaggc atgttttata gtgaattaaa ctttgctata aagaatataa gaaaatggag
      421 caaaataaaa agagttaaat caagtatggt taattttcca tctatatcca aagttgttcc
      481 acaaccttat ggtgttactc tcataatgtc accttggaat tatccctttc aattagcact
      541 tataccatta gtttggtcat tagcagcagg gaattgtgtt atattaaaac cttctgaata
      601 ttctgtgtca acatctagtg tagttaaaga catagttgaa aatacttttt caaaagaata
      661 tgttgcagtt gttcaaggaa gtcaagaaga aagtgaaaag ttactattgg aaagatttga
      721 ttatatattt tttacaggaa gtactaatgt tggtaaaata atcatgaaat cagcatcaga
      781 gcatttaact cctattactt tagaacttgg aggaaaaagt ccttgtatca ttttaaaaga
      841 tgctaatata gaccttactg ccaaaagact tacttgggga aaactaataa atgcaggaca
      901 aacctgcgtg gctccagatt atgttttagt gcatgaagat agaaaaaatg agttaataga
      961 gaaaataaaa tattatacta ataagtattt tggagataat ccatgtaata atgagcaatt
     1021 tcctaaaatc ataaatcaga gacattttaa tcggatatta tctcttattg ataaagataa
     1081 gatagtctat ggtggaaatt ataataagga gacattaaag atagagccaa ctatagtaga
     1141 caatgttaat tgggatgata atataatgaa ggaagaaata tttgggccta tatttcccat
     1201 tttaacatat aaagatttag atgaagtaat acaaaaaatt atacaaatgc caaatccatt
     1261 ggcactttat atttttacaa aaaataagta cctagaaaat aaacttttag aaatgattcc
     1321 agcaggcgga tgttgtatca atgatacagt tactcatata gctacgaatt acttaccttt
     1381 tggtggtatt ggtgaaagtg gtatgggctc atatcatgga aaagctggat tcgatacatt
     1441 tactcactat aagagtgtgt taaaaaaatt aaatttggat gtccctatta gatatgctcc
     1501 atacgataat aaattaatta aggttcttaa aaagataatg taggttatat tgtagaataa
     1561 taaatataaa taaaattgag tatttgtatt ctgaatatat tttattttta atttggtata
     1621 tttgttataa aagtggtgat tttgtgataa aatttaatta tatagaaata aggaggaaaa
     1681 aatgaaaatt aattggaata caaaatacac aacaatagca atttatacat ttataatagc
     1741 tgctagtagt attatatttt atctagtatc atcacaaatt gatgtatttt ctaataattt
     1801 agatgctata tttacaacat tacaaccttt tataatagga tttgctattg catatcttct
     1861 taattttatt ttaaagtttt atgaagacag aatttttata aaaagtgaga aattaaaaaa
     1921 actaaaacaa agttcaaaaa gaggcttggg tcttttatta acatatgcaa cagctacatt
     1981 gatactttac ttatttatgc atttcgtatt gccacaagta attgagagta ttgttggact
     2041 agcaaatgat atacctatgt atgtaaacaa tgcaactaag cttattgata aattaatgac
     2101 tgatttaaat cttgatgagc aatactttaa tttggcagtt gataagtgga atgagtttgt
     2161 tacatatatt ataaagtttg taacagattt aatcccaata ttaggaagta tgttaaagaa
     2221 tgtagcctct agtatatgga atattgtact aggattaatt gtttcagtat acttattaat
     2281 tgataaagaa aaattctatg gattaagcaa aaaaataact tatgcagtat ttacagaaaa
     2341 acaagctgcc agaattttag aattaactca tagaagtaac tatacatttg gaagattttt
     2401 aggtggcaaa atattagatt cattcattat aggtattcta acatttgtaa tacttacatt
     2461 agttaaaatg ccatatacat tattaatatc agttataatt ggtattacaa atattatacc
     2521 tttctttgga cctttatttg gagctatacc atctactcta atagtgatgt ttgtatctcc
     2581 tataaaagct ttctggttat tgttgattat attaataata caacagatag atggaaatat
     2641 tataggacct aaaatacttg gagattcaat tggtatatct gcattttgga ttttgttctc
     2701 cttattggtt gcaggaaaat tattaggttt tattggaatg gttataggag ttccaatgtt
     2761 tgcagtaatt tattctataa ttaaggatat tgttgaaagt aaattggaca aaaagggatt
     2821 accgacagat acttccgatt acatgtagct aaaaaatatt atgtataatt aaaaatatat
     2881 aaattaagca atatttaaag cactgagaaa gttaaactct tggtgctttt tagatataaa
     2941 attattatag aagaggtgtt ttttgtggca tttatagaat gtaaatttaa atctaaatat
     3001 actggaggag aaactgatat aattgtaatt ttgcctgtag caaatggaaa agaacttttt
     3061 agtggtaaag agatatatga ttttgaaggt aaatttaaaa cattatactt atttcatggt
     3121 ttagaagatg accaaagctc atggattaga tatactaatg tagagcatta tgctaaaaat
     3181 aaaaatatag ccctagtaat accaagagta gaaactagtt tttatacaga tatggcgtat
     3241 ggacaccaat attttacttt tgtaagcgag gaattaccta aatttgttag agctatattt
     3301 cctttatcag ataaaaggga agataacttt gtagctggta tgtctatggg gggatatgga
     3361 gctttaaaat tagcactttc aaaaccaaaa gagttttcgg cagttgcaag tttttctggt
     3421 tcgcctgata tgattcatga gttagaaaat caacaaatag aaaccaatgc agacatttta
     3481 tttcacgatt ttggtagacc agaagacgct agaaatagtg agaatgattt actttacata
     3541 cttaagaacc ttaaagaaag aaatgaagat attcctaaaa tttatcaatt ttgtggtgat
     3601 agagattttt tatataaaaa taatcagatg tttaaaaaat atgcagagtc tctgggtgta
     3661 gatgttgaat atgaagagtg tgtagggggg catgaatggc gtctttggaa tttatggata
     3721 aagaaattta tagatataat tgggtagtac acttatggta ttaacaggta tactataaaa
     3781 tatctttaaa tatgataaag actgaaatcc taaaatcaaa ttatgatttt aaaatttcag
     3841 tctataagaa tttaataaaa ttttattaag ttcttacacg agttattatt ggagtaaaat
     3901 tgtcaactat atctatatag tatttactca attcctctaa aatctcttcg cataaatccg
     3961 tactatgacc aagattaata agaaactgtt ttgtaaaatg ctttattaca gcttgagaag
     4021 atatatcgta cttgtgtgaa gtataaactc taattatttc aggtttcata gcaagtatac
     4081 caatacaaga aagtattaat tcatcatgtt ctatagattc tttatcatta acatatcttt
     4141 tcatgaccat ttcggttaca cttctttgat agcttaaaat agcttcttca taagctatat
     4201 ccaaataaaa atttctatat gcttcgtttt ttagaaggaa acaaaggtca gcattcatag
     4261 caagaaagaa catcatcata gtaccttctt catggtagtt atagattaaa gactgcattt
     4321 catttcttat atcttcatat attatagctc ctatttcgct tttacttgag aagtaatagc
     4381 ttattagacc taaatttata ttagctcttt ctgcaatttg cctagttgtt gtcttatgat
     4441 aaccttgctc aaaaaataat tctctagcag cacttataat actagctttt gtttctttgc
     4501 ccttttctga ttttgacata tttactgtgt atacctctct tttcaatctt tttttgaaaa
     4561 tttgctaact ataaatattg taatagaacc acctattata ggaaccaaaa ttctgtcaaa
     4621 tacagtaaga ataccaatca tatttaataa tgccaatata acacttacta taacagcata
     4681 gatagctcct ttttttgtag cgcctttcca gcaaagacca attacaaatg gtgcaaatat
     4741 tacacctgta cataatggag ccggccaaaa caataattct aataaactat caaatttaag
     4801 tgctatgatt gcacctatta tagctgtcaa agctgatgca atttgagaat actttagagt
     4861 attttttaaa tcattaaatt ctatattagg atgtaataat ttgttataaa tatctcttga
     4921 tataatagca ctcattgagg tcattaatga atcggcagta gacattatgg cagccaatat
     4981 agcagctaag aataatacag atattaaagg tggcaaagta gtcgatatca tttgaggtaa
     5041 aacctgaaca gatgatatgt ttggaaataa actaccacca atagctccaa ttattcctat
     5101 agggaaggca agaaataata gtataaatcc tgcaattaca ctacttttaa ctgcattttt
     5161 agcattatca gcacattgat atcttaaaaa actttcataa gaaaatattg agcctaaaac
     5221 taatggtaaa actgtataca taaaatcact aatcgattta tttcctggaa agaatggttc
     5281 ttttaccatt gattgtaaca taagtaaagg gttgtcgcca actaatttta agcttatata
     5341 agctactatt ggcaaaaaca ctatacaaat agcaagttga ataaatgctg atactgcaac
     5401 tccccacatt cctgatgtat aagtatatat aattataact ataactccta taattacagc
     5461 tatatcataa ggaataccaa atgcagtaga tacagaacca aaagaaatta attgactacc
     5521 cataatagct agtatagata ttggtgttac aagactttga taagctctta aaaatacact
     5581 atgaccatat ctagtttcaa tataatcagc aggtgttata tcacaagata agcttcttaa
     5641 ttttcctgcg aaaaaggcat ttataaagca agctaaagct gcacctatag tagaatacat
     5701 tccaacccaa agtcctcttt cagctcccca ttgaactcca ccaactaagc accctcctcc
     5761 aaaagatgta gcagcaatgg ttgcagctag tataggcaaa ggaagatttc tacctgcgat
     5821 taggaaatcg gatgctgttt taactttttt tgaaaaataa aaaccaatcc atatgtatat
     5881 tgcacacgta acaattaaaa gtaacatagt cttttctcct ttataaaata ttttaataaa
     5941 atatataaaa tatattt
//
LOCUS       DAMJYN010000154         5824 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.160, whole genome shotgun sequence.
ACCESSION   DAMJYN010000154 DAMJYN010000000
VERSION     DAMJYN010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5824)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5824)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5824
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.160"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(326..1009)
                     /locus_tag="PC466_003537"
     CDS             complement(326..1009)
                     /locus_tag="PC466_003537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HDF2770888.1"
                     /translation="MTSKSQMSESFFLCSLLAITGGFLDIYTYVVRGKVFANAQTGNI
                     VLFGLNIAEGNVKESFYYLIPILAFMLGVFIAEKIRKYFTNNKTKIHWRQVIIIIEMI
                     TILIVSFIPRGRFNMFVNVAISFICSMQVESFRKVNGNSFATTMCTGNLRSATETLFH
                     YIHTKNIFMIKKSLQYYAIIIFFISGAILGTFFTKIFVEKSILICFFILAVVFGIMFI
                     NKDDSFNEN"
     gene            complement(1351..1941)
                     /gene="zapA"
                     /locus_tag="PC466_003538"
     CDS             complement(1351..1941)
                     /gene="zapA"
                     /locus_tag="PC466_003538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HDF2770889.1"
                     /translation="MNKVMVKIHGAEYPMVGDKSEKFMISIADFVDKEMDKITRQNPK
                     LSLSVAAILTALNISDLLFECSDENEKLIKANEELSKKVGASNEELQLEIKSLKLTIA
                     EKEAENREAETKMKELIEIIENKKQEIFELSNTTEGSRAELDVYKNKIEELSTQLEEA
                     NERATIAENLASEFQNKAYDLQLKCTGLNNDAKNVE"
     gene            complement(1966..4359)
                     /locus_tag="PC466_003539"
     CDS             complement(1966..4359)
                     /locus_tag="PC466_003539"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HDF2770890.1"
                     /translation="MLVSLKWLRDYVDIDMDVKEFADKMTMTGTKVETIDYYGEEIEN
                     ILVGKILEIKQHPNADKLVVTKVDIGDKVVQIVTGATNISEGDYIPVAVNGSKLPGGV
                     EIKQTDFRGELSDGMMCSAAELGIDEHYIEEYKRGGIYILDHEDSYELGKDIKDVLGL
                     KDALIDFELTSNRPDCKCMMGIAREAAATIGTKVKYPEIEVKESDEEIDFKVEIDNPD
                     LCRRYVARMVTDVKIEPSPYWMQRRLTEAGVRPISNIVDITNFVMLELGQPLHAFDIN
                     QVETGRIVVRNAKDGEKLVTLDDVERTLDKDMLVITNGEKSLGLAGVMGGANSEITSN
                     TKTVLFESANFKPENIRMTAKKVGIRSEASSRNEKDLDPNLAEIAANRAAQLVEMLGA
                     GKVLKGVVDVYPNKPEPKKLVVNPQRINHLLGVDVPMEQFVGILESLEFKCNLVANDK
                     LEIDVPSFRTDMEQEADVWEEIARIYGFENIPSVQLEGNTTAGIKTSKQKFMDALKDN
                     STAVGLNEILTYSFVSPKGVDKIRVPEGNAKRNFVKLLNPLGEETSVMRTTLIPNMLD
                     VLSTNVSHKIEEVSAFECGHIFIPQDSELPKEENRMCVGMYGKDVDFFALKGTIETIL
                     VNVGFKGYEIEPQDNNTTFHPGRCAKIVYNNKYVGTLGELHPDVIENYNLGQRVYVAE
                     IDIDFVFDNSDRTKNYVPLPKYPSTSRDIALIVKDDVFVKQIEDIIKENGQGLVESYK
                     LFDVYKGSQIEAGYKSIAYSITYRSKDKTLTDEDVAKVHDKILSELSEKLNANLRSN"
     gene            complement(4376..5395)
                     /gene="pheS"
                     /locus_tag="PC466_003540"
     CDS             complement(4376..5395)
                     /gene="pheS"
                     /locus_tag="PC466_003540"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HDF2770891.1"
                     /translation="MQEKLLALREAALAEIKEAQSIESVESLRVKYLGKKGEITAILK
                     EMGKLSAEERPVVGKVANEVRENIELSINSKKEEINAIEKERKLKEEVIDVTQPGKVL
                     KVGKKHPITQIIDEVTDIFIGMGFSIAEGPEVETVENNFDALNAPKDHPSRDMSDTFY
                     INDGVLLRTQTSPVQVRTMRSQELPIKVIAPGRCFRSDSPDATHSPMFHQIEGLVVGK
                     DVTMAEFKGTMDIFVEKLFGSDIKTKFRPHNFPFTEPSAEVDVTCFKCGGKGCPMCKY
                     EGWIEILGSGMVHPNVLRNCGIDPEVYSGFAFGVGVERLAMLKYEIDDIRLLFENDMR
                     FLNQF"
     misc_binding    complement(5445..5679)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
BASE COUNT         1790 a         1110 c          611 g         2313 t
ORIGIN      
        1 tatttagtat atttctatta acttatatat tgattactgt attttaaatt cttcaattaa
       61 tttatatact gcttactaaa tttaaaacat tttaattaat ttgtacactg tttactatac
      121 ttgaaatact tctattaatc tatatattgc ctactatact taagacattt taattaattt
      181 atacactgct tactatactt aaaatacttc tattaactta tatattgctt actatatttt
      241 aaattcttta attaatctat acaatatttg ctatatataa agtatatcaa ataacagctt
      301 catttttttg taaatttaca gaaagttaat tttcattaaa tgaatcatct ttattgataa
      361 acataattcc aaagaccact gccaaaataa aaaaacatat tagtattgat ttttccacga
      421 aaatttttgt aaaaaaagtt cctaaaatag ctccagatat aaagaatata ataatagcat
      481 aatactgtaa actctttttt atcataaaaa tattcttagt atgtatataa tgaaataaag
      541 tttctgtagc acttcttaaa tttccagtac acattgtcgt tgcaaaacta ttcccattta
      601 cttttctaaa actctctact tgcattgaac aaataaaaga aatagcaaca tttacaaaca
      661 tattaaatct tcctctagga ataaatgaaa caataagtat tgtaatcatt tcaattataa
      721 tgataacctg acgccaatga atctttgtct tattatttgt aaaatacttt cttatcttct
      781 cggctataaa tacacctaac ataaatgcca aaataggaat caaataataa aatgattcct
      841 ttacattacc ttctgctata ttaagcccaa ataaaactat atttccagtt tgtgcattag
      901 caaagacttt acctcttacc acataagtat aaatatccaa aaatcctcct gttattgcca
      961 acaaagaaca taaaaagaat gattcagaca tctgactctt gcttgtcata tataaacctc
     1021 tcgctttcta atgatagata caaaatcaaa atcattttag attctatttt tcattgatat
     1081 aaaaaaatta tttatattta aatattatct atatttatac atcatttata tttatacatt
     1141 atttgtattt atatatcatt catatttatt tatatttaaa cattatctat atctatatag
     1201 catttatatt tatttacatt taaacattat ctatatttat atagcattta tatttattta
     1261 catttaaaca ttagctatat ttatatagca tttatattta tacattaaaa gaagctgtct
     1321 caaaaaacaa gagacagcaa atcttttagt ttattccaca ttttttgcat cattatttaa
     1381 ccctgtacat tttaactgta aatcataagc tttgttttga aactcagaag ctaagttttc
     1441 agctatagta gctctttcat ttgcttcttc aagttgagta cttaactcct caatcttgtt
     1501 tttataaaca tctaactctg ctctagaacc ttctgtcgta ttactaagtt cgaatatttc
     1561 ttgcttttta ttttctataa tctcaattaa ctctttcatc ttagtctcag cttcacgatt
     1621 ttctgcttct ttttctgcta tcgtaagctt taaagacttg atttctaatt gaagctcttc
     1681 attagatgct ccaaccttct tactcaattc ttcattagct ttaatcaact tctcattctc
     1741 atctgaacat tcaaataaaa ggtctgatat atttaatgca gttagtatcg cagcaactga
     1801 taagctcaat ttcgggtttt gacgtgttat tttatccatt tctttgtcta caaaatcagc
     1861 aatactaatc ataaacttct ctgatttgtc tccaaccatt ggatattcag cgccatggat
     1921 tttaaccatt actttgttca tcctaacctc ccccgacatt agttgttaat ttgatcttaa
     1981 gttagcattt aatttttcgc ttaattcact taatatctta tcatgcacct tagctacatc
     2041 ttcatctgtt agagttttat ctttacttct ataagttatt gaatacgcaa ttgacttgta
     2101 tccagcttct atttgagaac ctttgtaaac atcaaataac ttgtagcttt ctactaatcc
     2161 ttgaccattt tcctttatta tatcttctat ttgttttaca aatacatcat ctttaacaat
     2221 aagagctata tctcttgatg tagatggata ttttggtaat ggcacataat tctttgttct
     2281 atcagaatta tcaaatacaa agtcaatatc tatttcagcg acataaactc tttgacctag
     2341 attgtagttt tctataacat ctggatgcaa ttcacctaat gtacctacat atttattatt
     2401 atacactatt ttagcacatc taccagggtg gaaggtagta ttattatctt gaggttcaat
     2461 ttcataacct ttaaatccga catttacaag tatagtttct atagttcctt ttagtgcaaa
     2521 gaagtcaaca tctttaccat acatacctac acacattcta ttttcttctt taggtaattc
     2581 tgaatcttgt gggatgaata tatgtccaca ctcaaatgca gatacttctt ctattttatg
     2641 agatacatta gttgataaaa catctaacat atttggtatt aaagtagttc tcattacaga
     2701 agtttcttct cctaatgggt taagtaattt aacaaagttt ctcttagcat taccttctgg
     2761 tactcttatc ttatcgactc ccttagggct tacaaatgaa tatgttaata tttcatttaa
     2821 tcctacagca gttgaattat cttttaaagc atccatgaat ttttgttttg aagttttaat
     2881 tcctgctgtc gtatttcctt ctaattgtac agaaggtata ttctcaaatc cataaattct
     2941 agctatttct tcccatacat cagcttcttg ttccatatct gttctaaagc ttggtacatc
     3001 tatttctaat ttatcattag ctaccaaatt acatttaaac tctaatgatt ctaaaattcc
     3061 tacaaactgc tccattggta catctacacc taataggtgg ttaattcttt gaggatttac
     3121 taccaatttt ttaggttctg gtttatttgg atatacatct acaacacctt ttaaaacttt
     3181 tcctgctcct aacatttcaa caagttgtgc agctctattt gctgctatct ctgcaagatt
     3241 agggtctaag tctttttcat ttcttgaaga tgcttctgac ctaataccaa cttttttagc
     3301 tgtcattctt atgttttctg gtttgaaatt ggcactttca aaaagtacag tcttcgtatt
     3361 agaagttatt tctgagttag caccacccat tacaccagct aaaccaagtg atttttctcc
     3421 atttgttata actagcatat ctttatctaa tgttctctca acatcatcta atgttacaag
     3481 tttctctcca tctttagcat ttcttactac tattcttcca gtctctactt gatttatatc
     3541 aaaagcatga agtggttgac caagctctaa cattacgaag tttgttatat cgactatgtt
     3601 acttataggt cttactcctg cttctgtaag tcttctttgc atccaatatg gagaaggttc
     3661 tatttttaca tctgtaacca ttctagcaac atatcttcta cataaatctg gattatctat
     3721 ctcaactttg aaatctatct cttcgtcact ttcttttact tcgatttcag gatattttac
     3781 ttttgttcct atagttgcag ctgcttctct agctataccc atcatgcatt tacaatcagg
     3841 tctgtttgaa gttaattcaa aatctattaa agcatctttt aatcctaaaa catcttttat
     3901 atcttttcct aattcataag aatcttcgtg gtctaaaata tatataccac ctcttttata
     3961 ctcctcaatg taatgttcat ctatacctag ttcagctgct gaacacatca taccatctga
     4021 taattcacct ctgaaatcag tctgtttgat ttcaactcct ccaggtaact tagaaccatt
     4081 tacagctact ggaatataat ctccttctga tatatttgta gctcctgtaa ctatttgaac
     4141 aactttatct ccaatatcta ctttagttac aaccaactta tcagcatttg gatgttgttt
     4201 tatttctaaa atctttccaa ccaatatatt ttctatttct tcaccataat aatctattgt
     4261 ttcaacttta gttcctgtca ttgtcatttt atcagcgaac tcttttacat ccatgtctat
     4321 atcaacatag tctctaagcc attttaaaga tactaacatc tacataccct cctaattaaa
     4381 attgatttaa gaatctcata tcattttcga ataataatct aatatcatct atttcgtatt
     4441 taagcattgc aagtctttca accccaactc caaatgcaaa tccactgtaa acttctgggt
     4501 ctattccaca atttctaagc acatttggat gaaccatacc tgaacctaat atttctatcc
     4561 aaccttcata tttacacatt gggcaacctt taccaccaca tttgaaacaa gtaacatcaa
     4621 cctctgcact tggttctgta aatgggaagt tgtgaggtct aaacttagtt ttgatatcag
     4681 aaccaaacaa tttttcaacg aagatatcca tagttccttt aaattctgcc atagtaacat
     4741 cttttccaac aacaagccct tctatctgat ggaacattgg tgagtgtgta gcatctggcg
     4801 agtctgacct aaaacatcta cctggtgcaa ttacttttat tggtaactct tgacttctca
     4861 tagttcttac ttgaactgga gatgtttgag ttctaagtaa taccccatca ttgatataga
     4921 atgtatcgct catatctctt gatggatggt ctttaggagc gtttaatgcg tcaaagttgt
     4981 tttcaacagt ctcaacttct ggcccttctg ctatagagaa tcccattccg ataaatatat
     5041 ctgttacttc atctataatt tgagttattg gatgcttctt cccaaccttt aaaacttttc
     5101 ctggttgagt aacatctatc acttcctctt ttaattttct ttctttttca atagcattta
     5161 tttcttcttt tttagaattt atgctaagtt caatgttttc tcttacctca ttggcaacct
     5221 taccaactac tggtctttct tcagcagata atttacccat ttctttaagt atggcagtta
     5281 tctcaccttt ttttcctaag tacttaactc ttaaactttc tacactttct atgctttgtg
     5341 cttcttttat ttcagccaaa gctgcttcac gtaaagcaag taatttttct tgcacacata
     5401 tcaccctttc gtttttttgt ataaaaaaag cccctcaatc cctgtctagg gacgaaaggc
     5461 tatagtttcg cggtaccacc ctagtagttt aacaatttaa aaatcatcaa accacctcta
     5521 acaaacttaa cgcgtttttg acgtcaaagc ctactgtaaa atttcagctc tgttactcca
     5581 gagggaactt ctcatgacct cttagaaaac actcccagcc taggtgttta tctctttact
     5641 aagtttaatc aaaatacttt cctctttcat tgcatttaca atattatatt gtttatttta
     5701 gtattatatc atttccattc aaattatgtg actattttta atatatatcc aatacataat
     5761 taatttaatt attttttata taatatatat ctaatgcata attaactcaa ttatttttta
     5821 tata
//
LOCUS       DAMJYN010000155         5806 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.161, whole genome shotgun sequence.
ACCESSION   DAMJYN010000155 DAMJYN010000000
VERSION     DAMJYN010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5806)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5806)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5806
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.161"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            146..2197
                     /locus_tag="PC466_003541"
     CDS             146..2197
                     /locus_tag="PC466_003541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002449344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HDF2770892.1"
                     /translation="MDNRDSQHHMIHTSHENHDHHENHNHHSGHAHHHGNFKAKFFVS
                     LIFAIPIILLSPMMGVKLPFQFTFPGSEWVVLILSTILFFYGGKPFLSGGKDEIATKK
                     PGMMTLVALGISVAYIYSLYAFYMNNFSSATGHTMDFFWELATLILIMLLGHWIEMNA
                     VGNAGDALKKMAELLPNSAIKVMDNGQREEVKISDIMTDDIVEVKAGESIPTDGIIVQ
                     GQTSIDESLVTGESKKVQKNQNDNVIGGSINGSGTIQVKVTAVGEDGYLSQVMGLVNQ
                     AQNDKSSAELLSDKVAGYLFYFAVSVGVISFIVWMLIQNDVDFALERLVTVLVIACPH
                     ALGLAIPLVTARSTSIGAHNGLIIKNRESVEIAQHIDYVMMDKTGTLTEGNFSVNHYE
                     SFKNDLSNDTILSLFASLESQSNHPLAISIVDFAKSKNVSFTNPQDVNNIPGVGLEGL
                     IDNKTYKITNVSYLDKHKLNYDDDLFTKLAQQGNSISYLIEDQQVIGMIAQGDQIKES
                     SKQMVADLLSRNITPVMLTGDNNEVAHAVAKELGISDVHAQLMPEDKESIIKDYQSDG
                     NKVMMVGDGINDAPSLIRADIGIAIGAGTDVAVDSGDIILVKSNPSDIIHFLTLSNNT
                     MRKMVQNLWWGAGYNIVAVPLAAGILAFIGLILSPAIGAILMSLSTIIVAINAFTLKL
                     K"
     gene            2215..2763
                     /locus_tag="PC466_003542"
     CDS             2215..2763
                     /locus_tag="PC466_003542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1541 domain-containing protein"
                     /protein_id="HDF2770893.1"
                     /translation="MIKKLFFMILGSLLILSACSTGSKEENNGSKDKKEEEHMEHKSE
                     SKTPDDMKRTDDSKFKKGDEVTITAGHMPGMKNAKGTVKGAYKTYAYVVSYTPENGDK
                     KVNNHKWVVNEEVADAPKNGFEKGDTVKLEADHMPGMKGAEAQIDDVEKTTVYMVDYK
                     STENDKMVKNHKWMTTDELKSR"
     gene            complement(3138..3761)
                     /locus_tag="PC466_003543"
     CDS             complement(3138..3761)
                     /locus_tag="PC466_003543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDF2770894.1"
                     /translation="MLKEFNEILEQRKSVKEFDPNYKIPHKEMDEMIVKATKAPSSVN
                     MQPWRFVVVESDEAKEKLRPLIKFNTKQNDTSSAMVIVFGDLQCYEEGEFIYEQAVKN
                     GHMPQEVKEQMLPLVLENYKSHTRQSMNDIVKVDSSLAAMQFMLVAKQYGYDTNPIGG
                     FEHEEIGKTFGYDLDRYVPVMIVAIGKKAKEAYNSYRMPVEKVLEYK"
     gene            complement(3987..4082)
                     /locus_tag="PC466_003544"
     CDS             complement(3987..4082)
                     /locus_tag="PC466_003544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HDF2770895.1"
                     /translation="MFSTLFVTIIAPIVVGVILTLFSHWLNNREK"
     gene            complement(4508..5308)
                     /locus_tag="PC466_003545"
     CDS             complement(4508..5308)
                     /locus_tag="PC466_003545"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770896.1"
                     /translation="MNFDFLFDLISKGLIGTVLGKILFDVLNKLYKKMFKSRDADVYD
                     GATTTFIMASLVYSITCIINITILVVIYNEFKGNTNIEIFSFTGMIFVSLFTFFISIA
                     YGRIIFLLRNKFYLLQLPGENVYVLLKEGYDVVSTNGYELVNDIPAYRDLPYNKWEDY
                     IKYQQRYYDKTLDTKMNEVIYIHSKPIKRLFKVVSKKWIIGMILVPILYIILLCLCLN
                     SIITSPKFIISSMISLYALNFIILMQATININRSNDIDRYYGYYKCNF"
BASE COUNT         2054 a          856 c          866 g         2030 t
ORIGIN      
        1 attaaaatat gaatttattc gattaagcga tatgtatttt ctaattattt tggaaatcaa
       61 ttcgttttta cttaccccta ctgggtatat aatatgaact gattatatta cctatagatt
      121 tttataaatt ggaggaatca atttgatgga taatagagac tcacagcatc atatgattca
      181 tactagccat gaaaatcatg atcatcacga aaaccataat catcatagtg gccatgcaca
      241 tcatcatggg aattttaaag ctaagttttt tgtttcatta atttttgcaa tacctatcat
      301 tcttttatcg ccaatgatgg gcgttaaatt accttttcaa ttcacatttc caggttctga
      361 atgggtagtg ttaatattaa gtacaatttt attcttttat ggtggtaaac cgttcttgtc
      421 tggtggtaaa gatgaaattg ctacaaaaaa accaggcatg atgaccttag ttgctctagg
      481 tatttcagta gcttatattt atagcttgta tgctttttat atgaataact ttagtagtgc
      541 aactggtcat acaatggact ttttttggga attagcaacc ttaattttaa ttatgctatt
      601 aggacattgg atagaaatga atgctgtcgg aaatgctgga gatgctttaa agaaaatggc
      661 agaactatta cctaatagtg ctattaaagt tatggataat ggccaacgcg aagaagttaa
      721 aatatcagac atcatgactg atgatatcgt cgaagtaaaa gccggagaaa gcattccaac
      781 agatggtatt atcgttcaag gacaaacatc tatagatgaa tccctagtca ctggagaatc
      841 taaaaaagta caaaaaaatc aaaatgacaa cgtcatcggg ggttctatta atgggtctgg
      901 aacaatacaa gtcaaggtta cagctgttgg agaagatgga tatctttctc aagttatggg
      961 acttgttaat caagcacaaa atgataaatc tagtgctgaa ttgttatctg ataaagtagc
     1021 gggttattta ttctactttg ctgtaagtgt tggcgtgatt tcttttattg tctggatgct
     1081 cattcaaaat gatgttgatt ttgcattaga acgtcttgta actgtgttag tcattgcttg
     1141 tccacatgct ttaggcttgg caataccttt agtcactgca cgttctactt caattggtgc
     1201 acataatggt ttaattatta aaaatagaga gtctgtagaa atagctcaac atatcgatta
     1261 tgtaatgatg gataaaactg gtactttaac tgagggtaac ttttctgtga atcattatga
     1321 gagctttaaa aatgatttga gtaatgatac aatattaagc cttttcgcct cattagaaag
     1381 tcaatctaat cacccattag ctataagtat tgttgatttt gcgaaaagta aaaatgtttc
     1441 atttactaat ccacaagacg ttaataatat tccaggtgtc ggattagaag gtctaattga
     1501 taataaaaca tataaaataa caaatgtctc ttatcttgat aaacataaac ttaattatga
     1561 cgatgacttg tttactaaat tagctcaaca aggtaattca atcagttatt taattgagga
     1621 tcaacaagtc attggcatga ttgctcaagg agatcaaatt aaagaaagct caaaacaaat
     1681 ggtagctgat ttactatcaa gaaatattac accagtcatg cttacaggtg acaataatga
     1741 agtggcacac gctgtcgcaa aagaattagg tattagtgat gtccacgcac aactcatgcc
     1801 agaagataag gaaagcatta taaaagatta tcaaagtgac ggtaataaag tcatgatggt
     1861 cggagacggt atcaacgatg cgccgagtct tataagagcc gatattggta tagcaattgg
     1921 tgcaggcaca gatgttgcag tggattcagg tgatatcata cttgttaaaa gtaatccatc
     1981 agatattatt catttcttga ccctttcaaa taatactatg agaaaaatgg tgcaaaactt
     2041 atggtggggt gcaggttata atattgttgc tgtaccttta gcagctggta ttttagcatt
     2101 tatcggcttg attttatcac ctgcaatagg ggctatttta atgtcattaa gtacgattat
     2161 cgttgcaatt aatgccttta cattaaaatt gaaataaaag ataggagttt tattatgatt
     2221 aaaaaattat tttttatgat attaggatca ttactaatat tatcagcttg ctcaacgggt
     2281 agtaaagaag aaaataatgg ttctaaagat aaaaaagaag aagaacacat ggaacataaa
     2341 agtgaaagca agactccaga tgatatgaag cgtacagacg atagtaaatt taaaaaaggg
     2401 gatgaagtta ctattacagc aggacatatg cccggcatga aaaatgctaa agggacagtt
     2461 aaaggtgctt acaaaaccta tgcttatgta gtgagttata cacctgaaaa tggtgataag
     2521 aaagtaaata accacaaatg ggtcgttaat gaagaagttg cagatgcccc taaaaatgga
     2581 tttgaaaaag gtgatacagt taaattagaa gctgaccata tgcctggtat gaaaggtgca
     2641 gaagctcaaa ttgatgatgt agaaaaaaca accgtttata tggtggatta taaatcaacc
     2701 gaaaacgata aaatggttaa aaatcacaaa tggatgacaa ctgacgaact taaatctcgt
     2761 taatatcttt cattttagtt ctttaaagta tttagttagt gattgataaa tgcaatgaga
     2821 atcccctttg ttaaatagac aagtaaacaa ataaaattta tggtcactct catatccaca
     2881 ataatgagag tggccatttg tttagaaaaa ttaaatgatt tttatgaaaa tgaggggatc
     2941 ttttataatt tatcaatgga attcgaaaaa tataaaatag aatagtgaat gtattgagct
     3001 ttctcgttta tcaagaaaag ttattctaaa ttagcaggta aagtcacagt tgctataaat
     3061 tcaacaacta tatatttatg attagagtgt accttaaaca acccaatagc tatattaata
     3121 atataaatac tattaattta cttatactct aagacttttt caactggcat tctatatgaa
     3181 ttatatgctt ctttagcttt tttcccaatt gcaacaatca ttactggaac ataacgatcc
     3241 aaatcataac caaacgtttt accaatttct tcatgttcaa aaccaccaat tggattagta
     3301 tcatagccat attgttttgc aactaacata aattgcattg cagctaaact actatctact
     3361 ttaacaatat cattcatact ttgacgtgta tggcttttat agttttctaa aacaagaggt
     3421 aacatttgtt cttttacttc ttgaggcata tgaccatttt taacagcctg ttcatatata
     3481 aactcacctt cttcataaca ttgtaaatca ccaaaaacga ttaccattgc tgaagatgta
     3541 tcattttgtt ttgtattaaa tttaattaat ggacgtaatt tctctttagc ctcatcactt
     3601 tctactacaa caaaacgcca aggttgcata tttactgaag aaggcgcttt tgttgctttc
     3661 acaatcattt catccatttc tttatgtgga attttataat taggatcaaa ttcttttaca
     3721 gattttcttt gctctaaaat ttcattaaac tcttttagca tcacttaacc ttctttcttt
     3781 agtgtctatt taaaattata gacttaaaat actttataac caaatacttc ttttcactaa
     3841 attttatgat tttgcatttc tccactaacc agtgttataa tttagttaac aaatagtgta
     3901 ctagcatgat aaacaccgag cccgataact actgcgaata gttattgggc tcttttggtg
     3961 tattagctat atatgtcgcc gctaaattac ttctcacgat tattcagcca atgagaaaat
     4021 aatgtgagta taactcctac tacgatagga gctataatag ttacaaatag tgtactgaac
     4081 atgatgtcac ctccttccat gctaaataca gcacagaagt gaacgacgac ttttgtatta
     4141 taccatttct aataattgag ttacagatga cttccgataa gtcatcttat gttaaaacta
     4201 ttaatatcaa aacaagaaga aactcgtttc aaatctatct taaatcttag gcttatctct
     4261 attaattttc cctactttaa caactaaata aatagcatta ataatcatta aaattgtata
     4321 tggaattagt atgtatggat tatctgattg atatacaaaa attaatccaa gtaaaaagat
     4381 agaatttaag atagttgcta taaaataccc cttatctaat actgtatttt tttcaaaata
     4441 agcacttctt ttttaagaca ttttatcata attgttttat tgcttatttt ttctttcgtc
     4501 ttctttatta aaaattacat ttataataac cataataacg atctatatca ttacttctat
     4561 tgatattaat agttgcttgc ataagtatga tgaaattcaa agcgtacaat gaaatcattg
     4621 aagaaataat aaatttggga cttgtaataa tactattaag acaaagacat aatagtatta
     4681 tatataaaat tggtaccaaa atcataccta taatccattt tttacttact actttaaata
     4741 atctcttgat aggtttgcta tgtatataaa taacttcgtt catttttgtg tctaatgttt
     4801 tatcataata tctttgctga tatttgatat aatcttccca tttattatat ggtaagtctc
     4861 tatatgctgg aatatcattt accaattcat aaccatttgt gctaacaaca tcataacctt
     4921 ctttcaataa aacataaacg ttttctcctg gtaattgtag aagatagaac ttatttctta
     4981 ataaaaagat gatccttcca tatgcaatag aaataaaaaa agtaaacaaa ctaacaaata
     5041 tcattccagt aaatgaaaaa atttcgatat ttgtattacc tttaaactca ttatagataa
     5101 caacaagaat cgttatattg attatacatg ttattgaata aactagagag gccattataa
     5161 atgttgtagt tgctccatca taaacatcag catctctact tttaaacatt ttcttataca
     5221 gtttatttaa tacatcaaaa agtattttac caagaactgt tccaattaat cctttactta
     5281 ttaaatcaaa taaaaaatca aaattcattt tatattctcc tttcttttat atccaataat
     5341 aacttaagat tagtaagatt gagttattat tggatataaa agttcaatcg atttttacta
     5401 aagttatatg tccattttgt agaatttaaa tatcactttt ttatgtttta ttttaaaata
     5461 gagaattcta tatagaattc tttagaattc aaaaattcta tacctcttca atctcagtag
     5521 tggcgtatct tctcgcaatt tagtatttta agcgtaaaaa tgccaaaagg tgtaatttta
     5581 cactacaaga gattgtattt ataaatgccg tcacagtagt ttttcaaagg atatgcagtg
     5641 aaccttagct atgctaagtg ccatgtatgg cattgttctc tcttatcctg tttcaataga
     5701 attccaaaaa tcctattgat aaaaaataat tgaatttact caatcgtttg aagtcataag
     5761 tttatacata attaacttta attttcattt ctaatcacat tttttt
//
LOCUS       DAMJYN010000156         5786 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.162, whole genome shotgun sequence.
ACCESSION   DAMJYN010000156 DAMJYN010000000
VERSION     DAMJYN010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5786)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5786)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5786
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.162"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            661..2070
                     /locus_tag="PC466_003546"
     CDS             661..2070
                     /locus_tag="PC466_003546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBOAT family protein"
                     /protein_id="HDF2770897.1"
                     /translation="MIFSSLIFLFLFFPVTLICYYLANPKYKNVMLLLASIAFYAWGE
                     PKYIFLMILSIIVNYIFGIKVSGSKNKKMWVVLSVIYNISILAVFKYSNFFIDNINFL
                     FNTDITIPEVKLPLGISFFTFQIMSYVIDVYRNDAKVQRKLANLALYISLFPQLVAGP
                     IVRYQTVADSIEYREHNWDKFTQGVNRFVVGLGKKVILANQLGVIADGVFNKSAGDLS
                     RLEVWLGIVCYTLQIFYDFSGYSDMAIGLGKMFGFEFLENFNYPYISQTVSEFWRRWH
                     ISLGTWFKDYVYFPLGGSRVSKAKLYRNLFVVWFLTGMWHGASWTFIIWGLYYGILIS
                     VEKAFLEKFLYKMPRIVRHIYLLLIVMIGWVFFRVDDLPAAIKFIGIMFGAGNYPVIS
                     DAFNVFIIEYWYIIVGAILLSTPIVKVVKSLLIKKNKNTLNSTLYQVTNVVFIVSCMF
                     IVIIMLSSSTYNPFLYFRF"
     gene            2086..3288
                     /locus_tag="PC466_003547"
     CDS             2086..3288
                     /locus_tag="PC466_003547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770898.1"
                     /translation="MSKKKPRIVAISFLIIVFGFFILNFTLPKKKLSITENRNLAKFP
                     TVENLKKCDFIAKFEEYFNDHFAFRDEMISINTRTQANLNKTKVGNYYLGKDNWILGM
                     FPEILDQKQLSRYEKSINYLSNLSKDMGKNVYFTMMPHKTNMLKHLYPKYVDNMDNID
                     INLKNFKNRLNPDLIKYIDMDEYFLSNYSDKERENLYFKTDHHWTGYGAFEGFKMMAS
                     NMDLGLSKQDLDKHFSSYKKSIITDKKFIGSYNQNIDMLIKENEYVVYMTKDNQDYSF
                     DINGEEKEEKEEKEVYATERDNKEWDYGGAYIRGAKTNILTIKNPKALVDKKILIFRD
                     SYQAPTTLLFADMFKEVEIADPRNINSIYKTYKEIIEESNADIVMFMYNSSGFDSMID
                     SMIDKGIK"
     gene            3489..4472
                     /locus_tag="PC466_003548"
     CDS             3489..4472
                     /locus_tag="PC466_003548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770899.1"
                     /translation="MKEVFNVHIMQSQNKKIKQKYYLTKDGWLLGNFAKLLSDYHIKS
                     YSKAINNLSKLNRKKDFYFVSLPHKTNMLKHLYPSGIEGKNNIDINKENLEKQLTDIN
                     FLDIDDYFYRSFTEKEREKFFLKTDHHGNSLGAFEEYKFILDKLDLGLSKSEIDSHLK
                     RYSTRYVNDKVFIGSYNKKMGYPLKKKESISYVEISDANYKYFISNGTKNTEINENII
                     KAKLKDKREWDYGGAYMRGCDCHILKIRNSSSLTNKKALIFRDSYQAPMTWMLADTFK
                     ELEILDPRYIKNIDMTYDEIIKNSNANVVLFMYNSFGFAGMIQEMIDKGIA"
     gene            complement(4922..5365)
                     /locus_tag="PC466_003549"
     CDS             complement(4922..5365)
                     /locus_tag="PC466_003549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770900.1"
                     /translation="MKKNMLYLGIVYFICGILLVLLATFTEFSFEAFIWGLSGAALGP
                     GICMIFQYMYWSKPERAVDYEEKIKNQRIEMNDERRVMLRDKAGRITNQIMSYVLVIL
                     IFIVSILSVFSVMVISKWVLVVLGLLILFQFICSVVVYNKLDKKL"
     gene            complement(5524..>5786)
                     /locus_tag="PC466_003550"
     CDS             complement(5524..>5786)
                     /locus_tag="PC466_003550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDF2770901.1"
                     /translation="SDVSWSEFIHQLKYKANWYGRQIVKVGKFFASSQICNKCGYKNE
                     EVKDLNIREWICPSCNETHDRDINASINILKEGLRLITIQNK"
BASE COUNT         2271 a          712 c          787 g         2016 t
ORIGIN      
        1 tgtaaaaggg ttcttttttt ttataataaa atagctataa aaatatacat atcaaatcaa
       61 attaagaagt atttcatttc taagaaatat cctaacataa aaacaaaaaa tgttcataaa
      121 tttaactatt aacatagata atttttagaa aagtatctaa attttcaata aatagtaact
      181 tttttacaac aaatggaaac tatggaagca ataattaaaa taaaatttat aatcaatcat
      241 aattatttag tataatgatt cgatattatt ttaaagtatt tgtcatttaa aacaaacttg
      301 cgataaaagc atatctgaaa gtattctgat tctaatactt aataaagagt tctttttaca
      361 gttatagata taaacaacat ctatcttaat agactgtata gaggcacaat caaaggtaaa
      421 cacatatagt taagtaatat gtccttgatt tttctttatt ataatagctt tattaattca
      481 ttttaatatt acatcatttt aaaaaaatta tatgaaaagt caaaatttac atatagatta
      541 attaaacttg taaaaacaca tataaattca tacaattaag tacttaaaac ttgaaaatac
      601 ttactttgct atatatttta gataaagata taattgattt ggttaagaaa ggagtctaat
      661 atgatattca gtagtttaat atttttattt ttattctttc cagtcacact catttgctat
      721 tacttggcaa atcctaagta taaaaatgtt atgttacttc tagcaagtat tgcattctac
      781 gcatggggag aaccaaaata tatttttttg atgatactat caataatagt aaactatata
      841 tttggtatta aagtttctgg cagtaaaaat aaaaaaatgt gggttgtgct ttctgttatt
      901 tacaatatat ctattcttgc tgtatttaag tatagcaatt tttttataga taatattaat
      961 tttttattca atacagatat aactatacct gaggttaaat tacctttagg tatctcattt
     1021 ttcacattcc aaataatgag ctatgtaata gatgtatata gaaatgatgc taaagttcaa
     1081 agaaaattag ctaatttagc attatacata agtttattcc ctcagcttgt agcaggtcct
     1141 attgttagat atcagactgt tgcagatagc attgagtata gagaacacaa ttgggacaaa
     1201 tttactcaag gtgtaaacag atttgttgtt ggtcttggaa aaaaagtaat tctagcaaat
     1261 caattaggtg taatcgcaga tggtgtattt aataagtcag ctggagattt atcaagactt
     1321 gaggtatggc taggtatagt ttgctataca cttcaaatat tctatgactt tagtggctat
     1381 agtgatatgg ccattggttt aggtaagatg tttggatttg agtttttaga aaatttcaac
     1441 tatccatata tctctcaaac agtatctgag ttttggagaa gatggcatat atctttaggt
     1501 acttggttta aagactatgt gtacttccca ttaggtggaa gtagagtctc taaggcaaaa
     1561 ctatatagaa atctatttgt agtatggttt ttaaccggga tgtggcatgg agctagttgg
     1621 acttttatta tatggggtct atattatgga atattaatat cagtagaaaa agcattctta
     1681 gaaaaatttc tatataagat gccaagaatt gtaagacaca tatatctact tcttatagtc
     1741 atgattggat gggtattttt tagagttgat gatttaccag cagctattaa atttataggt
     1801 attatgtttg gtgctggaaa ttatccggtt atcagtgatg cattcaatgt atttataatt
     1861 gaatattggt atataattgt tggggcaatc cttctatcaa ctcctattgt aaaagttgta
     1921 aaatcattat taattaagaa aaataaaaat acattaaata gcacattata tcaagttact
     1981 aatgtggttt tcattgtttc ttgtatgttt attgtaataa taatgttaag tagctcaacc
     2041 tataatccat tcttatattt tagattctaa ttgggaggta taaacatgag taaaaaaaaa
     2101 ccaaggattg ttgccatttc atttttaatt atagtatttg gatttttcat actaaacttc
     2161 acacttccaa agaaaaaatt aagtataact gaaaatagaa atcttgcaaa atttccgact
     2221 gtagaaaatt taaaaaaatg tgactttata gccaagtttg aagaatattt taatgaccat
     2281 tttgcattta gagatgaaat gatatcaata aatacaagga ctcaggctaa tttaaataaa
     2341 actaaggtag gtaactatta tctaggaaaa gataactgga tattaggtat gtttccagaa
     2401 attttagacc aaaaacaatt aagtcgatac gaaaaatcca ttaattattt atctaatcta
     2461 agtaaagata tgggaaaaaa tgtgtatttt acaatgatgc cacataaaac taatatgtta
     2521 aaacatttgt atcctaaata tgttgataat atggataata tagacataaa tttaaagaat
     2581 tttaaaaata gattaaatcc agatttaatt aaatatatag atatggatga gtatttttta
     2641 agtaactatt cagataaaga aagagaaaat ttatatttta aaactgacca tcattggact
     2701 ggatatggag catttgaagg ctttaaaatg atggcatcaa atatggactt aggtctatct
     2761 aagcaagatt tagacaagca ttttagtagc tataaaaagt ctataattac tgataagaaa
     2821 tttataggaa gttataatca aaatatagat atgctaatta aagaaaatga atatgtagtt
     2881 tatatgacaa aagataacca agattatagc tttgatataa atggagaaga aaaagaagaa
     2941 aaagaagaaa aagaagttta tgcaactgaa agagataata aagagtggga ttatggtggt
     3001 gcatacatta gaggagctaa aactaatata ttaactataa aaaaccctaa agcattagta
     3061 gataaaaaaa tactaatatt tagagattca tatcaggctc ctacaacact tttatttgct
     3121 gatatgttta aagaagtaga gatagcagac cctagaaata taaactcaat atataaaaca
     3181 tacaaagaga taatcgagga aagtaatgca gatattgtaa tgtttatgta taatagttct
     3241 gggtttgatt caatgataga ttcaatgata gataaaggaa taaagtagta aataaaaagc
     3301 ctctattaaa ttcaaaattt aatagaggct ttttattgtt tattttttat tgctttggta
     3361 aaaataaact aatcaaaata aaagtaagga gatgtagcat attgaacaaa agacatagtc
     3421 tacctatagt atcagtgata ttattgatgg tcttaattat ctttaataat aaccaaaatt
     3481 atattacaat gaaagaagtt tttaatgtcc atattatgca gagtcaaaat aaaaagatta
     3541 aacaaaagta ttatctaact aaagatggat ggctattagg caactttgct aaattattat
     3601 ctgattatca tataaaatct tactccaaag ccattaataa cttgagtaag ttaaatagaa
     3661 aaaaagattt ttactttgtt tcacttcctc ataagacaaa tatgcttaag cacttgtatc
     3721 caagtggtat agaaggtaaa aataatatag atattaacaa agaaaactta gaaaagcagt
     3781 taacagacat aaatttctta gatatagatg attactttta tagaagtttt accgaaaaag
     3841 agagagaaaa attcttttta aaaacagacc atcacggaaa ttcattagga gcatttgaag
     3901 aatataagtt tattcttgat aaattagacc ttggcttatc taaatcagaa atagatagtc
     3961 atttaaaaag atacagtact cgatatgtaa atgacaaggt ctttataggt agttataata
     4021 aaaagatggg atatccactt aagaaaaaag agtctataag ctatgttgaa ataagtgatg
     4081 caaattacaa atattttatt agtaatggta ctaaaaatac tgagattaat gaaaatatca
     4141 taaaagcaaa attaaaagat aaaagagaat gggactatgg tggagcttat atgagaggtt
     4201 gtgattgtca catacttaag attagaaatt caagctcttt aactaataaa aaggccctta
     4261 tatttagaga ttcgtaccaa gcacctatga cttggatgtt ggctgatact tttaaggaac
     4321 tcgaaatact agatcctaga tatataaaaa atatagatat gacctatgat gagataatta
     4381 aaaacagtaa tgcgaatgta gttttattta tgtataatag ctttggattt gctggaatga
     4441 tacaagaaat gattgacaag ggaatagcat aacaatttga atcagctcct ttttatacaa
     4501 aaaatagttc tcaataattc ctaatctata tgataattta gtacatctct ttaacaataa
     4561 aaataaaatc acaaaaattc ttataccatc acttatcttt atgataaatt ggttgagaaa
     4621 aaattttata atttatatga tatgcaatct taattaattc tttatctact gcaaccttta
     4681 ataaaagaaa ccatccaaga ctattaatat gaatttatat aaaaattact ttcaaataaa
     4741 gtactgcagt atttttattt aaagtatcta taatctttaa ccacaaaaag ccacaaaata
     4801 caatgtatac ttatggcttt ttataaattt atataattgt atataaagat atattctaaa
     4861 actgtcttaa gaatctaaag tttaaaaatc caatattttt attgtgaatt taaacttttt
     4921 attacaactt tttatctaat ttattgtata caacaacact acaaataaat tgaaataaaa
     4981 taagcaatcc aagaacaact aaaacccact tgcttattac cattacagaa aatacactca
     5041 atatagaaac aataaatata agaattacaa gaacatagga catgatttga ttagtgatac
     5101 gtccagcttt atcacgtaac ataactcttc tttcatcatt catctctatc ctttggtttt
     5161 ttatcttttc ttcataatct actgctcttt caggcttact ccaatacata tattgaaaaa
     5221 tcatacatat acctggacct aaagcagctc cagataatcc ccaaataaaa gcctcaaatg
     5281 aaaactcagt aaacgtagcc aataaaacaa gtaaaattcc acaaataaaa tatactattc
     5341 caagatataa catattcttt ttcattttta ctcctcctca taaataaata tttcttcaat
     5401 actcatctga acctcccatg actaaagtca cagggttcct gcttcacaga attttgcata
     5461 ctaaaatatg tcttactaat tctccacagg ccatccccgt agttcctacg gttcttacat
     5521 acgttattta ttttgaattg ttattaatct taatccttct tttaatatat ttatacttgc
     5581 atttatatct ctatcatgag tttcattaca actaggacaa atccattctc ttatatttaa
     5641 gtccttaact tcctcgtttt tatacccaca tttattgcat atttgtgaac ttgcaaagaa
     5701 tttgcctact tttacaattt gtctaccata ccaattagcc ttgtatttta attgatgaat
     5761 aaattctgac catgatacat cagaaa
//
LOCUS       DAMJYN010000157         5694 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.163, whole genome shotgun sequence.
ACCESSION   DAMJYN010000157 DAMJYN010000000
VERSION     DAMJYN010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5694)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5694)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5694
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.163"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            35..886
                     /locus_tag="PC466_003551"
     CDS             35..886
                     /locus_tag="PC466_003551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase"
                     /protein_id="HDF2770902.1"
                     /translation="MKNIISAKELISKLEKNDNLVVIDCRFDLINRTYGIDSYKKGHI
                     KGSFILDIDKDLSSPTKEHGGKNPLQDPLILKEKLEKMGVDNDTTIVTYDDGDLNGAC
                     RLFFQLKHLGLKNVYVLDGGITSFVKEGGELEEKVNIPSCTGKEIRPNINNDLVVPME
                     YVKSKLYKKDTVIIDCRANERYQGLVEPAYSKAGHIPSAKNYFCKDLIKSDFENGSLK
                     DIEFLKKFFKDLNNYDEVILSCGSGISACVNSLALRELDIPHKIYIGSFSDWISYDDN
                     EIKTGQE"
     gene            complement(1019..2632)
                     /gene="ggt"
                     /locus_tag="PC466_003552"
     CDS             complement(1019..2632)
                     /gene="ggt"
                     /locus_tag="PC466_003552"
                     /EC_number="2.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyltransferase"
                     /protein_id="HDF2770903.1"
                     /translation="MKFNAYQHKYSSIRNVVYAKNGAVATSTPLASQAGLEILKKGGN
                     AVDAAVATAATLAVVEPTSNGIGGDAYALVWIEEEKRLYGLNSSGFAPENMELKNYNN
                     MKEMPKYGFGAVTVPGIPAAWSELNKKYGKLSLMECLSPAINYAREGYVVSPNVAKVW
                     KKSYELYEKELIGEEFKPWFDTFSKDGKAPEAGDIFICEEQASTLEEIANTQAESFYR
                     GRLADKIDEYSKKFNGAIRKSDLECFYPTWVEPISTEYKGYKIFEIPPNGHGITVLMA
                     LNILKELELEGNIENVEDIHKIIESLKLAFADSKTYVTDIEHMKVKIQELLSQEYAKK
                     RSLLIDNKEALYPTAGEPYCGGTVYLCTADKDGNMVSYIQSNYINFGSGIVIPRTGIA
                     LHSRGNNFNLDPKHHNVVKPFKKPYHTIIPGFLGKEDKAIGPFGVMGAFMQPQGHIQV
                     LTNMIDFGLNPQEALDAPRWQWIKGKEIEVEPEMPKHIIDSLIEKGHEIKVIHDTVDM
                     GRGQIIFKTEQESYICGTESRCDGHIAVY"
     gene            complement(2857..4794)
                     /locus_tag="PC466_003553"
     CDS             complement(2857..4794)
                     /locus_tag="PC466_003553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2770904.1"
                     /translation="MTLFRIAMQNVKNSFFNYLMYFISIVFSVFVFFSFKSIEYNEAL
                     SSLGEKTRMSINTSSIVIVVFVFLFIYYSNSFFFNRRRREVGTYSLLGMRKNQIGKIF
                     LYETFLMGIVAILIGIFLGLLFSKLMTMMLVKLMNEMIVVNMNLSIKALVKTLAVFLI
                     IFIVIGIRNTIVIRNKRIIELFNKYPEKYKFKKFIKLKCVLGVLLIAISYLMSISYFI
                     AENIMLSVFILVTIIPGTFLFFSSTMYMIIDAVKKRKSFYYKGQNLIAFSELGFKLKS
                     NSSVLAVIAILIATSVTMLGFTISLYYDIDRNISENYKYSYTINLGNSYVNNEIDKLL
                     YKYKKDNKIIFDKTIELIDKDINIEMYYKNGNSYIEDRTSVDIIRESDFKKLRQYQNN
                     NYEELTSKESVYYVSDSYKKMFFKDFEIEKINLYIKDTNEYDINLFKVQKSILEPEIN
                     SQATFDLIVVKDDVFNQLKLHGNSRLIRLIDIKNEKKELDLTLKFKNIVSENMKFTYP
                     FNFTSSIESYNNLIKLSGLMLFIGIFLSVVFLLCTGSIILFKQLSNIYDDKERYIMLI
                     KLGANNKDIEKIISKQLKIIFLMPLVVGTVHNLFAMSIAQKFIPRSLLVPIIITLVIY
                     FIGYFIYYFLTLKYALNMIKE"
     gene            complement(4781..5548)
                     /locus_tag="PC466_003554"
     CDS             complement(4781..5548)
                     /locus_tag="PC466_003554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003722224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2770905.1"
                     /translation="MEEILSVENIKKEYGRKGSKHEALKGITFKVYKGEFVGIMGSSG
                     AGKSTLLNIISTMDLPSSGDIYINGKNTIKMKQNELADFRRDNLGFVFQDSNLLDTLT
                     IKENIMLPLSLKNERVSVIENRIKEISKELNIESILDKYPGEVSGGQKQRGAVCRAIA
                     TKPSLVLADEPTGALDSKSARDLLNCLLKLNKDSNKTILMVTHDAISASFCNRILFIK
                     DGIIFTEIVKGESNREFYNKIVNTVSLIGGVNKNDFI"
BASE COUNT         1925 a          912 c          637 g         2220 t
ORIGIN      
        1 aataaagata atataaacat aggaggtaca ttctttgaaa aacattattt cagcaaaaga
       61 acttatatca aaactagaaa aaaatgataa tctagttgta atagattgca gatttgatct
      121 tatcaataga acttatggta ttgattctta taaaaaagga catatcaaag gcagttttat
      181 cttagatata gacaaggatt tatcatctcc tacaaaagaa catggtggta aaaatccttt
      241 acaagaccct ttaatactaa aagaaaaatt agaaaaaatg ggtgttgata atgacactac
      301 gattgtaact tatgatgatg gagatttaaa tggagcttgc agattatttt tccaattaaa
      361 acatttgggg cttaaaaatg tctatgtact agatggggga ataacatctt tcgtaaagga
      421 aggtggagaa ttggaagaga aagtgaatat accaagttgt acaggtaagg aaattagacc
      481 aaatataaac aatgatttag ttgttccaat ggaatatgtt aagtctaaat tatacaaaaa
      541 agatactgta ataatagatt gccgtgctaa tgagagatac cagggtttag ttgaacctgc
      601 ttactcaaaa gctggtcata taccaagtgc aaaaaattat ttttgtaagg atttaataaa
      661 aagtgacttt gaaaatggct cacttaaaga tatagaattt ttaaaaaaat tctttaaaga
      721 tttaaataat tatgatgaag taattttatc ttgtggttca gggatatctg cttgtgttaa
      781 cagtcttgct cttagagaac tggatatacc tcacaagatt tatattggta gctttagtga
      841 ctggattagt tatgatgaca atgaaatcaa aactggtcaa gaataaggct cataatctat
      901 ataaaatcag catatgatag cttaaatttt gtaaaggcgt cagtcattgt agactttcgc
      961 ctttactaat tatttcatat actctttaaa tttattatat atattttagt tgataatatt
     1021 aataaactgc aatatgacca tcacatcttg attccgtccc acaaatataa ctttcctgtt
     1081 ctgttttaaa tattatttga cctcgtccca tgtcgacagt atcatgaatt acttttattt
     1141 catgaccctt ttcaattaat gaatctatta tatgctttgg catctctggt tcaacttcta
     1201 tttcctttcc ttttatccac tgccatcttg gagcatctag cgcctcttgt ggatttaatc
     1261 caaaatcaat catatttgtt aacacttgaa tatgtccttg tggttgcata aaagctccca
     1321 ttacaccaaa tggacctatt gctttatctt ctttacctaa aaatccaggt attatagtat
     1381 gataaggttt tttaaatggt tttactacat tgtggtgttt agggtctaaa ttaaaattat
     1441 ttcctctact atgtaaagca atcccagttc ttggtatcac aattcctgaa ccaaaattta
     1501 tgtaattgct ctgtatatat gaaaccatat ttccatcctt atctgcagta caaaggtata
     1561 ctgtaccacc acaatatggc tctcctgcag ttggatacaa agcctcttta ttgtcaatta
     1621 ataaacttct ttttttggca tactcttggc ttagtaattc ctgaatcttt accttcatat
     1681 gctctatatc agttacatat gttttagaat ctgcaaaagc taattttaaa ctctctataa
     1741 ttttatgtat gtcttctaca ttttctatat ttccttctaa ttccaattct tttaatatgt
     1801 taagtgccat taaaactgtt attccatgac catttggtgg gatttcaaat attttatatc
     1861 ccttatattc tgtacttata ggttctaccc atgttggata aaaacactct aagtcactct
     1921 ttcttatagc cccattaaat tttttagaat attcatctat tttatcagca agtcttcctc
     1981 tataaaagct ttcagcctga gtatttgcta tctcttctaa tgtacttgcc tgttcttcac
     2041 atataaatat atctccagcc tctggagctt taccatcttt agaaaatgta tcaaaccatg
     2101 gtttgaactc ttctccaata agttcttttt catagagttc atatgatttt ttccatacct
     2161 tagctacatt aggagatact acgtatccct ctcttgcata gtttatcgct ggagataagc
     2221 attccattaa gctaagttta ccatattttt tatttaattc tgaccaagct gcgggtattc
     2281 caggtacagt tactgctcca aacccatatt ttggcatttc tttcatatta ttataatttt
     2341 ttaattccat attttctgga gcaaagccac tagaatttaa accatacaat cgtttttctt
     2401 cctctatcca aacaagggca tatgcatctc ctccaatccc attgcttgta ggttctacta
     2461 ctgctaatgt ggcggctgtt gcaactgctg catcaacagc atttccaccc ttttttagta
     2521 tttcaagtcc agcttgagat gctaatggtg ttgatgttgc aactgctcca tttttagcat
     2581 acacgacatt tcttattgat gagtatttat gttggtaggc attaaacttc ataaatttca
     2641 gctcctcgtc attttttatt tgatattctg cttagattta ttatataaca tcaagtaatg
     2701 taactgatac aaaatgatat aaaatataga ctttttccta actttaattt tatctttaaa
     2761 taaatatctt aaactcaatt ctagtatttt ctatctgcac ttaaataagt tattttattc
     2821 aaaacatata tctaattctt ttgacttaaa aataatttat tcttttatca tgtttagagc
     2881 atattttaaa gttaaaaaat aatatataaa atatcctata aaataaatga ctagagttat
     2941 gataattggt acaagtaatg accttggtat aaacttttgt gctatagaca tagcaaataa
     3001 attatgaact gtacctacaa ctaatggcat taaaaatata atttttaact gttttgatat
     3061 tattttctca atatctttat tatttgctcc aagttttatt aacataatat atctttcctt
     3121 atcatcatat atatttgata attgtttaaa taagattata ctacctgtac ataaaagaaa
     3181 tactacagac aaaaatatgc ctataaacag cattagacca cttaatttta tcaagttatt
     3241 ataactttca atacttgatg taaaattaaa aggataagta aatttcatat tttcacttac
     3301 tatattttta aattttaaag tcaaatccag ttcttttttt tcatttttta tatcaattaa
     3361 tcttattaat ctagaatttc catgtaattt taactgatta aatacgtcat cttttactac
     3421 aattaaatca aacgtagctt gtgaatttat ttctggctcc aagatgcttt tttgtacctt
     3481 aaacagattt atatcatact catttgtatc tttaatatac aagtttattt tttcaatctc
     3541 aaagtcttta aaaaacattt ttttgtatga atcagaaaca tagtacacag attcctttga
     3601 agttaattct tcataattgt tattctgata ttgtcttaat tttttaaaat cactttctct
     3661 aataatatct acagaagttc tatcttctat ataactattt ccatttttat aatacatttc
     3721 aatatttata tctttgtcta taagttctat tgttttatca aagattatct tattatcttt
     3781 tttatattta tataataatt tgtcaatttc gttatttaca taagaatttc ctaaatttat
     3841 ggtataactg tatttataat tttcacttat gttcctatct atatcgtaat aaagtgatat
     3901 ggtaaaccct agcatagtta cactcgtagc tattaatatt gctattacag ccaatacact
     3961 actattgctc tttaatttaa atccaagttc agaaaatgca attaaattct gtcccttata
     4021 ataaaaactt tttctcttct taacagcatc aataatcata tacatagttg atgaaaaaaa
     4081 taaaaaagtt ccaggtatta ttgtaactaa tataaaaact gaaagcataa tattttcagc
     4141 aataaaataa ctaattgaca ttaaataaga aatagctatt aataaaacac caagtacaca
     4201 ttttaacttt ataaattttt taaacttata cttttctgga tatttattaa ataactctat
     4261 aattctctta tttctgataa ctatagtatt tcttattcca ataactataa atattattaa
     4321 aaataccgct agtgtcttaa ctaaggcctt tatacttaag ttcatattta ctactatcat
     4381 ttcattcatt aattttacaa gcatcatagt cataagcttt gaaaataaca gtcctaaaaa
     4441 tatacctatt agtattgcaa ctatacccat caaaaaagtt tcatataaaa atatttttcc
     4501 tatctgattt ttcctcattc caagtaaact ataagttcct acttctcgcc tacgtctatt
     4561 gaaaaaaaat gagtttgaat aatatataaa taaaaataca aataccacta ttacaattga
     4621 acttgtatta atactcatcc tagttttttc tccaagtgaa ctcaacgctt cattatactc
     4681 tatagattta aaactaaaaa atacaaatac actaaataca attgaaataa agtacattaa
     4741 ataattaaaa aaactattct ttacattttg cattgcaatt ctaaataaag tcatttttat
     4801 taactcctcc aattaaggaa actgtattta ctattttatt atagaactct ctgttacttt
     4861 ctccctttac aatttctgtg aatattattc catcctttat aaagagtatt ctattgcaaa
     4921 aactcgcact tatagcatca tgagttacca tcaatattgt tttattgctg tctttgttta
     4981 attttaatag acaattcaac aaatccctag cagatttaga atctaatgct cctgtaggct
     5041 catctgcaag tactaatgat ggttttgttg ctatagctct acatacagct cctctttgct
     5101 tttgtccacc agaaacttcg ccaggatatt tatctaatat agattctata tttaattctt
     5161 ttgaaatctc ttttattcta ttttctatta ctgatactct ttcatttttt aaagaaagag
     5221 gcaacattat attttctttt attgtaagtg tatccaaaag attagaatct tgaaatacaa
     5281 agcctagatt atcacgtcta aaatctgcca attcattttg cttcatttta atagtattct
     5341 ttccatttat ataaatatct cctgatgaag gtaaatccat tgtagaaata atatttaaaa
     5401 gtgttgattt accagcaccg gaagacccca taataccaac aaattctcct ttataaacct
     5461 tgaaagttat tccttttaga gcttcatgtt ttgaaccttt tcttccatac tcctttttta
     5521 tattttcaac agataatatt tcttccatag ttaataatca cctttcatca caattagtta
     5581 tttatcaatt ctcacaaata tattatatat attaaaatgg cttttaaaca tttaattata
     5641 ttaatttaag gttacatttt cgtaagtatt aattatattt cttcaaattt attg
//
LOCUS       DAMJYN010000158         5424 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.164, whole genome shotgun sequence.
ACCESSION   DAMJYN010000158 DAMJYN010000000
VERSION     DAMJYN010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5424
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.164"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            <1..519
                     /locus_tag="PC466_003555"
     CDS             <1..519
                     /locus_tag="PC466_003555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HDF2770906.1"
                     /translation="MNKPDGYISATTDKYDPTVLDLIDLSYLAFEPFPVGRLDKDTEG
                     LLVLTNDGKLSHRVLSPKKHVPKTYYAKIDGVVTEEDVEAFLEGVVLDDGYKTMPSQL
                     NILKSDDESEIELTIHEGKFHQVKRMFESVGKKVVYLKRLSMGNLKLDESLELGEYRE
                     LTDEEVKLIEER"
     gene            546..1907
                     /gene="rlmD"
                     /locus_tag="PC466_003556"
     CDS             546..1907
                     /gene="rlmD"
                     /locus_tag="PC466_003556"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HDF2770907.1"
                     /translation="MSVKKKDVIEFEVDKMEFGGTSLSQVGDRVIHMKGGISGQKVRA
                     GVKKVRSKKAEVKMIELLENSPLETEETCKHFRECGGCTLLSVPYEKQLEIKEKQVMD
                     LFLKQDLFGFQFLGIEGSPENKYYRNKMEYTFGDEVKNGPLTLGLHKKGKHIDIQTVE
                     ECMLVDEDFSKILVSSVEFFNEKKLPYYRTMNHKGYLRHLVVRKGIHTNEIMVNIVTS
                     SQEDFDMNEFKDMLLGIDLKAELVGVLHTINDGLADAVQCDELRVLYGRDYIQEEILG
                     LKFKISPFSFFQTNTKGAEVLYSIARDFIGDYNDKVVFDLYSGTGSIGQVMAGAAKKV
                     YGIEIVEEAVVAANENAKLNGLTNCEFIAGDVAKVVKDLKDKPDLIIVDPPRPGIHKD
                     AIRDICGFGAKEIVYISCNPKSLVVDLVDFKGYGYEIKMVKCMDMFPNTPHCETVVKL
                     IRE"
     gene            2231..2386
                     /locus_tag="PC466_003557"
     CDS             2231..2386
                     /locus_tag="PC466_003557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770908.1"
                     /translation="MFSKNEILKKLIEEYDVKTTTDIQDMLKDLFTNTIHQIFPLSNF
                     NGLNIIY"
     gene            2430..3464
                     /locus_tag="PC466_003558"
     CDS             2430..3464
                     /locus_tag="PC466_003558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YHYH domain-containing protein"
                     /protein_id="HDF2770909.1"
                     /translation="MFKKKLIAVAMSITMISVGSFSYAHSGRTDSSGGHRDNKNKSGL
                     GSYHYHCGGYPAHLHNNGGCPYTGGGSSSGTTTSVNNEEKQKRSVGEKGYNQGYEDGY
                     KGNYSSSNYSGDYSDTYESKYSEGYEKGKAKLEEEEKVAKETGYNLGLTGAKSNNTYE
                     KEVLKNAYDTGYSTGYNEYKTKKIEEYKAKGIEDSNKDKEKMTFEENIDSEFIDAYNN
                     AYDEIQEQLKNDYTTQGFESAIKGERFDTSTIGNVKYANWFKEGYDNGKVKLPKAKES
                     VYNQGYNEEDFSIPYEMKSIETKLKGVYDEGLEKREEEKSRNATYGVGAGTAAVVAGV
                     VYKNKKRKKI"
     gene            3551..3754
                     /locus_tag="PC466_003559"
     CDS             3551..3754
                     /locus_tag="PC466_003559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4236 domain-containing protein"
                     /protein_id="HDF2770910.1"
                     /translation="MGFNFRKSINLGGGLKLNLGKKSVGISAGVKGARVSVNSKGRKS
                     ATLSIPGTGISYTKTSTKKRKPK"
     gene            3925..5085
                     /locus_tag="PC466_003560"
     CDS             3925..5085
                     /locus_tag="PC466_003560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp27"
                     /protein_id="HDF2770911.1"
                     /translation="MKLSKTLLAIGMSVSLLIASCPTSNALSSINSIKGTNKYETAGL
                     IADKQNYDIAILINSENGLSDGLSASGLSGAKNAPILLTKKDTIPSETLKRLEKVKEV
                     YLIGGKNSIGASVQKILSDKKISINRISGTDRIDTSHKVAKEIGRVSTVKKVILTNAF
                     KGEPDAMSVASIAVRDKSPIVLTDGNTTSFATDGLETYAIGGKVSMSDKLINETKATR
                     IGGVDRYDTNKQIINKFYNGSKEFYIASGTDLVYSLVGSTIAQKTPIVLVGNGSNKSI
                     LKNASKITAIGNIDDVIIKQCLNITNNVGDSNTGIVKDTNSNNTNKPSNEPSSNNPGL
                     TDKSTVYVTPNGKSYHLTKNCSTLKRSKTINKVTLKQAKSQGKIDPCNVCVK"
BASE COUNT         2152 a          532 c         1058 g         1682 t
ORIGIN      
        1 atgaataaac ctgatggata tatatcagca actacagata aatatgaccc aacagtatta
       61 gatttaattg atttatcata cttagctttt gaaccatttc ctgttggaag gttagataaa
      121 gacacagagg gattattagt tttaactaat gatggaaagc tttctcatag agttttatct
      181 cctaagaagc atgtgcctaa gacttattat gcaaaaattg atggagtagt tactgaagaa
      241 gatgtagaag cttttttaga aggtgtagtg cttgatgacg gatataaaac tatgccatca
      301 cagttaaata tattaaaaag tgatgatgaa tcagaaatag agcttacaat acatgaaggt
      361 aagtttcacc aagtaaaaag aatgtttgaa agcgtaggca aaaaagtagt atacttaaaa
      421 agattgtcta tgggcaattt aaaattggat gaaagtttag agttaggtga gtatagagag
      481 ttaacagatg aagaagtaaa attgattgaa gaaagataat aaagatacta tagtaaattg
      541 gaggaatgtc tgtgaagaaa aaagatgtta tagaatttga agtagataaa atggaatttg
      601 gtggtacatc tttaagtcaa gttggagata gagttatcca tatgaagggt ggaataagtg
      661 gtcaaaaggt gagagctgga gttaaaaaag ttagaagtaa gaaagctgaa gttaagatga
      721 tagaattatt agagaactca ccacttgaaa ctgaagaaac ttgcaagcac tttagagagt
      781 gtggaggatg tacactattg tctgtgccat atgaaaaaca attagaaata aaagaaaaac
      841 aagttatgga tttattttta aagcaagatt tatttggatt tcagttttta gggatagaag
      901 gaagtccaga aaacaaatat tatagaaata agatggaata tacttttgga gatgaagtaa
      961 aaaatggacc tttgacatta ggtcttcata aaaaaggaaa gcatatagat atacaaactg
     1021 ttgaggagtg tatgttggtt gatgaagact tctcaaagat attagtttct agtgtagagt
     1081 ttttcaatga aaaaaagctt ccttattata gaacaatgaa tcacaaagga tatttgagac
     1141 atcttgtagt tagaaaaggg attcatacta atgagattat ggttaatata gtaacttctt
     1201 ctcaagaaga ttttgatatg aatgagttta aagatatgct tttagggatt gatttaaagg
     1261 ctgagttagt aggtgtactt catactatta atgatggttt agcagatgca gtccaatgtg
     1321 atgagttaag agtattgtat ggaagagatt atatacaaga agaaatttta ggtcttaagt
     1381 ttaagatttc accattttcg tttttccaaa ccaatactaa gggagctgag gttctttata
     1441 gtattgctag ggattttatt ggagattaca atgataaggt tgtatttgac ttgtatagtg
     1501 gtactgggtc tattggacag gttatggctg gtgctgctaa gaaagtgtat ggtattgaga
     1561 tagttgagga agctgttgtt gctgctaatg agaatgctaa gttgaatgga cttactaatt
     1621 gtgagtttat tgctggggat gtggctaagg ttgttaagga tttaaaggac aagcctgatt
     1681 tgattattgt tgaccctcct agaccaggca ttcataagga tgctattagg gatatttgtg
     1741 gatttggtgc taaggagatt gtttatattt cttgtaatcc taagtctttg gttgttgatt
     1801 tggttgattt taaggggtat ggttatgaga ttaagatggt taagtgtatg gatatgttcc
     1861 caaatacgcc acattgtgag actgtagtta aacttattag agaataacag ggtttcagac
     1921 ttttatattg tgtcttaaaa gtagatttgc cacctatttg ccaccataat tatttttggg
     1981 tggcaaattt attctacaat gatttcaaaa atatttacca tctggtttct catgttatta
     2041 gttacatgta aatatgtatc catagttgtt gaagttttag catgtccgag tatatgctgg
     2101 atatctttta tattagtacc attttctaat aacatagtat cagggttttt aaaataaagt
     2161 gtgtattctt ctagagtagt gataattaaa atatcaaata tcactataca aaggaaagtg
     2221 cacccttttt atgtttagca aaaacgaaat attaaaaaaa cttattgaag aatatgatgt
     2281 caaaacaact acagatattc aagatatgct aaaagattta tttacaaata caattcatca
     2341 aatatttcca ttgtcgaatt ttaacggttt aaacataata tattgactga tataataaaa
     2401 tcatagaata ttttaggggg aaatagatta tgtttaagaa aaagttaata gctgttgcaa
     2461 tgagtataac tatgattagt gtagggagct tttcgtatgc tcattcagga agaactgatt
     2521 catcaggagg tcatcgtgat aataaaaata aatctggatt aggaagttat cactatcatt
     2581 gtggtggtta tccagcccat ttacataata atggtggttg tccttatact ggaggaggaa
     2641 gcagttctgg aacaacaact tcggttaata atgaagaaaa gcaaaagagg tctgttggag
     2701 aaaaaggata taatcaaggg tatgaagatg ggtataaagg aaattatagt tcatcaaatt
     2761 atagtggaga ttatagtgat acatatgaat caaagtactc agaaggatat gaaaaaggta
     2821 aggctaaatt agaagaggaa gaaaaggtgg ctaaagagac tggatataat ttagggctta
     2881 caggtgctaa atctaataat acatatgaaa aagaagtttt aaaaaatgct tatgataccg
     2941 gatattcaac tggatacaat gaatataaga ctaaaaagat agaagaatat aaagctaaag
     3001 ggatagagga tagcaataaa gataaagaaa aaatgacatt tgaagaaaac atagattctg
     3061 aatttataga tgcttataat aatgcttatg acgaaataca agaacaatta aaaaatgatt
     3121 acactactca aggatttgag agtgctatca aaggagaaag atttgacaca tcaactatag
     3181 gtaatgttaa atatgctaat tggtttaaag aaggatatga taatggtaag gttaagttac
     3241 ctaaagcaaa agaaagtgta tataatcaag gttacaatga agaagatttt agtataccat
     3301 atgaaatgaa gtctattgaa actaagttaa aaggtgtata tgatgaaggt ttagaaaaaa
     3361 gagaagaaga gaaaagtaga aatgctactt atggggttgg agctggaaca gcagctgtag
     3421 ttgctggagt agtatataaa aataaaaaac gtaaaaagat atagatgcta gatataccaa
     3481 tgatgacaag tgtataacaa atataatttt aagtataaat atttaaaata tagaagggaa
     3541 ggttatatct atgggattta actttaggaa aagcataaat ctaggaggag gactcaaatt
     3601 aaatttaggt aagaagagtg taggtataag tgctggtgtt aaaggtgcta gagtgtcagt
     3661 taattcaaaa ggaagaaaat cagctacatt gagtatacct ggaactggaa tatcatatac
     3721 aaaaactagt acaaagaaac gtaaacctaa ataaatattt gatatactaa gaaatagact
     3781 gttacaaata gtctattttt tagtatatag atttaaaaag tgacaaaatt ttgaaatata
     3841 aactaatttc ataaaggaaa atattctttt atgtagaatt ataatattta agtaatatta
     3901 taaaatttat aggaggattt cattatgaaa ttaagcaaaa cactattggc aatagggatg
     3961 tctgtttcat tattgattgc tagttgtcca acatcaaacg ctcttagttc tattaattca
     4021 ataaaaggta caaataagta tgaaacagca ggtttaatag cagataaaca aaattatgat
     4081 attgcaatac ttattaattc tgaaaatgga ttatctgatg gattgtcagc aagtggattg
     4141 tcaggagcta aaaatgcccc aatattgtta actaagaaag atacaatccc ttcagaaaca
     4201 ttaaaaagat tagaaaaggt aaaagaagta tatctaattg gaggaaaaaa ttcgatagga
     4261 gcatcagttc agaaaatatt aagtgataaa aaaataagca taaatagaat aagtggaact
     4321 gatagaatag atacaagtca taaagttgca aaagaaatag gaagagtaag tacggttaaa
     4381 aaagtaatat taactaatgc ttttaaaggc gaaccagatg ctatgagtgt tgcttctata
     4441 gcagttagag ataaatctcc aatagtatta actgatggaa atactacaag ttttgctaca
     4501 gatggattag aaacttatgc aattggtgga aaagtcagta tgagtgataa gttaataaat
     4561 gaaactaaag caacaagaat aggtggagta gatagatacg atacaaataa acaaataata
     4621 aataaatttt ataatggctc aaaagaattt tacatagcaa gtgggactga tttagtttat
     4681 tctttagttg gttctacaat tgcacaaaaa acacctatag tgttagttgg aaatggaagt
     4741 aataagagta tattaaaaaa tgcaagtaaa ataactgcta ttggaaatat tgatgatgtt
     4801 attataaaac aatgtttaaa tataactaat aatgttgggg attcaaatac aggtattgta
     4861 aaagatacta attcaaataa tacaaacaaa ccaagtaatg agcctagctc taataatcct
     4921 ggattaactg ataaaagtac agtatatgta actcctaatg gaaaatcata tcatctaaca
     4981 aaaaattgtt ctacactaaa aagaagtaaa acaataaata aagtaacatt aaaacaagct
     5041 aagtcacaag gtaaaataga cccttgtaat gtttgtgtaa aataatgtat tagccaaata
     5101 tatattaaaa aagacaatta attaagattg tcttttttat tgaagaaata taaatttata
     5161 ttatgtatta ttaaaaagaa aattattaat tataaaaaat aataataaag acgataagta
     5221 ttaaaatttt atgtttccaa tatttatgat ataattaata tggcaaggaa taaatatttg
     5281 aaaaagctat gagtggtgtt tccatggaag tttcttcact ttcttatgag aggaggtgaa
     5341 aactatggaa aatctaatga tgagtattat aactggtgtt atagccagtt acatttacga
     5401 taaattaaag agccactctg acca
//
LOCUS       DAMJYN010000159         5400 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.165, whole genome shotgun sequence.
ACCESSION   DAMJYN010000159 DAMJYN010000000
VERSION     DAMJYN010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5400)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5400)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5400
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.165"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            177..1013
                     /locus_tag="PC466_003561"
     CDS             177..1013
                     /locus_tag="PC466_003561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDF2770912.1"
                     /translation="MNIKKIFNNNVVVSSLEDGTEIIVTGAGVGFKKKVGDLIDENLI
                     SKKYFVQDDQRDKYNQILNKTSIEYFKISEEIIEKANEVLNTQVNDSIILALTSHIEF
                     AVQREKQGIKLPNLILNETKQLYREEFKFGLWAIDEIEKRIGIKLPEDEAGYIAIHII
                     NGLENSQKDEGINILEFSKQVIQIIEEVHGFKLDVNSLNYTRLITHLKFFVQRILRKE
                     TYNDSDIEDMYKLVNKNYNKPKVCTEEIAALVLDRFEYKISKEEELYLMIHINKITNS
                     GC"
     gene            1366..2943
                     /locus_tag="PC466_003562"
     CDS             1366..2943
                     /locus_tag="PC466_003562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDF2770913.1"
                     /translation="MKKNKLGLWNFFQMLGKTFMFPIALLSVSGMMLGLGAGFTDPKM
                     IEMVPFLGNEYVNLVLNFMLTIGLFAFNNLGALFAMAIPLGLLKKEKEFGAFSGLVGF
                     IAMHIGTNFYLTRADLLVPAEQMSTNGQAMIMGIQTYNTSVLGGIVAGLIVYAIYDKV
                     SNLKIPESLGFYSGPRLVPIVSLIVMSIVGLLIPIVWPPFFNAFQSLGRWISSAGPLG
                     YFSYAVAERVTIPFGLNHLVTSVFRFTPIGGTAVIDGETYFGTLNMFMAYVENNQIIP
                     LDLAGKMEQGKLMIQYGLAGAALAIYRTAKPENRKALKGLLISGVLTVIIGGISEPIE
                     FLFLFISPALFAFHTFMNGLANMVLPYLGVLMGFTGDLIAFISFGVLRGTATGWPIAV
                     LVAVLYFAIYYFVFKWAIIKFNIKTPGREDKEIKVSEGNGSDFKNLSTYKGQQMISAL
                     GGQSNILSLDNCVTRLRLKLQDVSLINEDAIKEAGGIAVVKLDEHTIQVIIGTQVYSL
                     RKQMDKAMEGHLEACND"
     gene            2936..4120
                     /locus_tag="PC466_003563"
     CDS             2936..4120
                     /locus_tag="PC466_003563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HDF2770914.1"
                     /translation="MINFDKKVDRLGTYCTQWDYVEDRFGKKDLLPFTISDMDLEFPF
                     EITEVLQERLNHRVLGYSRWKHDDFRNSVTNWYIKRFNCSVDSNWIYYSPSVMYSISK
                     LIEMLSNEGDGILINTPAYNAFYDVITNNNRNIIKSHLVNRNGFYSIDFNDFEKKCKK
                     SKIFILCNPHNPTGRVWSELELVKMIGICKNNDVKIISDDIHMDIVYDNRMTPILNVA
                     KDYLDSVFICTSASKSFNIPALTGSYVIIPNEGIRNKFENITRYRDFVNSPAILAILA
                     TMVCYDDCEYWLDELLKYLKENLKYTIDYIKDNLEPLKLVMPEGCYFAWIDFSELKIS
                     GEKFQKLLMDIGEVAIMSGSVYGEEGEFYLRLNVACSREKLEDGLNRIKKTMDYIAKR
                     TL"
     gene            4138..4737
                     /locus_tag="PC466_003564"
     CDS             4138..4737
                     /locus_tag="PC466_003564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HDF2770915.1"
                     /translation="MGYLKTMVDVMTTEMNAIRCLIDEAGIEYESIVSEIANCEGKVI
                     FMGVGKSAHIGKKLAATFASTGTPSFFVHATEAVHGDLGMIESKDITILISNSGNSME
                     VVNCIKYIKAIGSKTIAFTSNRNSVLAKECDYALIYPAKDEADHLNLAPTTSSTITLV
                     LGDSIACALSKSSNFGSSDFYKYHPGGSLGEKLKTANNG"
     gene            4761..5231
                     /locus_tag="PC466_003565"
     CDS             4761..5231
                     /locus_tag="PC466_003565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF2770916.1"
                     /translation="MFKMFKKKSIKSPISGKVIELSKIQDGVFSQKIMGEGVAIDSTG
                     DIVYAPINGKIVVVAETKHAFVIELENGMELLIHVGLDTVNLKGEGFEALVSMGEQVK
                     EGTPMLKINRPLIELKGISLITPVTITNHSEYNMNTCNVGNSVEGGKDTVIEFK"
BASE COUNT         2027 a          566 c         1032 g         1775 t
ORIGIN      
        1 aaaatatgat aaaatatgac aaattaattg atgacaataa aaaatatttt gttattgtag
       61 tattataggg taaattgcaa aatatatacg aaagtaaaat tttaaatatt gacattaaat
      121 taaatatact atactatgta agtgtgatga gagaattttt ttagagggga tttatagtga
      181 atataaaaaa gatatttaat aacaatgtag tagtaagctc cctagaagat ggcacagaaa
      241 taattgtcac tggtgctgga gtaggattta agaaaaaagt aggcgatttg atagatgaaa
      301 atttgatttc taagaaatat tttgttcaag acgatcaaag ggacaaatac aatcaaatac
      361 ttaataagac ctctattgaa tactttaaaa tttcagaaga aattatagaa aaggctaatg
      421 aagttttaaa tactcaagtg aatgattcaa taatattagc cttaactagt cacatagaat
      481 ttgctgtcca aagagaaaaa caaggtataa aattaccaaa cttaatattg aatgagacaa
      541 aacaacttta tagggaagaa tttaaatttg gattatgggc aattgatgaa attgaaaaaa
      601 ggataggaat aaaattgcct gaagatgaag caggatatat tgctattcac ataatcaatg
      661 gtttggaaaa ttctcaaaaa gatgaaggta ttaatatact agagttttca aaacaagtta
      721 ttcagataat tgaagaagta catggattta aattggatgt aaattcatta aattatacta
      781 gacttataac tcacttaaag ttttttgttc aaaggattct ccgaaaagaa acttacaatg
      841 atagtgatat tgaagatatg tataagttag tgaataaaaa ttacaataaa cctaaagtgt
      901 gtactgaaga aattgcagca ttggtattag acagatttga atataagatt agtaaagaag
      961 aagaattata tttaatgatt cacataaata aaataacaaa cagtggttgt taggattgta
     1021 actgataaag caggcaaaac ctaagtcaat gagcttaact attagattaa gttttttgat
     1081 ttaggttttt ttattagata caatcaaaat acagacagtg acttttagga ttgtaactgg
     1141 ttaagcaggc aaaacctaaa tcattgaatt taactattag gttaagtttt ttgatttagg
     1201 tttttttatt agatacaatc aaatacagac agtgactttt aggattgtaa ctggttgagc
     1261 aggcaaaacc taaatcatta aacttaatta ttaaattaag ttttttgatt taggtttttc
     1321 tataaatttg attatgtttt tagataaaaa taggagggga aaattatgaa aaaaaataag
     1381 ttaggtttat ggaacttctt ccaaatgtta gggaaaacgt ttatgttccc aatagcacta
     1441 cttagtgttt ctgggatgat gctaggactt ggggcaggtt ttacagaccc taagatgatt
     1501 gaaatggttc catttctagg gaatgaatat gttaacttag ttttaaactt catgttaaca
     1561 ataggattat ttgcatttaa caacttggga gcattatttg caatggcaat tccactagga
     1621 ttattaaaaa aagaaaaaga gtttggtgct ttttcaggat tagtaggatt tatagcaatg
     1681 catataggta caaattttta tttaacaaga gctgatttgt tagtaccagc agaacagatg
     1741 tcaactaatg gtcaagctat gattatgggt atacaaacat ataatacaag tgttttaggt
     1801 ggtattgtag caggattaat tgtttatgca atatatgata aagttagtaa tttaaagata
     1861 ccagaatcat taggattcta cagtggacca agattagttc caattgttag tttaatagtt
     1921 atgagtatag ttggattatt aatacctatt gtttggccac catttttcaa tgcattccaa
     1981 agtttaggaa gatggatttc ttcagcagga ccattaggat atttttcata tgcagtggca
     2041 gaaagagtta caattccatt tggactaaat catcttgtaa catctgtatt ccgttttaca
     2101 ccaataggtg gaactgctgt tattgatgga gaaacgtact ttggtacatt gaacatgttt
     2161 atggcatatg tagaaaataa tcagattata cctcttgatt tagctggtaa aatggaacaa
     2221 ggtaaattga tgattcaata tggattagct ggtgctgcat tggctatcta ccgtacagca
     2281 aaaccagaaa atagaaaggc acttaaagga cttttaatat caggagtgtt gacagttatt
     2341 ataggtggta taagtgaacc aatagagttt ctattcttat tcatatcacc agcattattt
     2401 gctttccata catttatgaa tggtctagca aacatggtac ttccatactt aggcgtgttg
     2461 atgggattca caggagattt aattgcattt ataagttttg gtgtgttaag aggaacagct
     2521 acaggatggc caatagcagt attagtagca gttttatatt ttgcaatata ctattttgta
     2581 tttaagtggg caattattaa gtttaatata aagaccccag gacgtgagga taaagaaata
     2641 aaagtatctg aaggaaatgg ttcagatttc aaaaatttgt ctacatataa aggacaacaa
     2701 atgatatctg ctttaggtgg tcaatctaat atattatcac tagataattg tgtaactaga
     2761 ttgcgtttaa aactacaaga tgtatcatta ataaatgagg atgcaattaa agaggctggt
     2821 ggtatagcag ttgttaaatt ggatgagcat acaatacaag taattatagg aactcaagtg
     2881 tattctttaa gaaagcagat ggataaagct atggaaggtc atttggaggc atgtaatgat
     2941 taattttgat aaaaaagtag accgattggg tacatattgt acccagtggg actatgtaga
     3001 agatagattt ggtaagaagg atttgcttcc ttttacaatt tcagatatgg atttagagtt
     3061 tccatttgaa ataacagagg tgttgcagga aaggttaaat catagagttt tgggatacag
     3121 tagatggaaa catgatgatt ttagaaattc agttacgaat tggtatatta aaagatttaa
     3181 ttgtagcgtt gatagtaact ggatatatta tagtccaagt gtaatgtatt caattagcaa
     3241 acttattgag atgttaagta atgaaggaga tggaatcctt ataaatactc ctgcatacaa
     3301 tgctttttat gatgtgataa caaataacaa tcgtaatatt ataaagtcac atcttgtaaa
     3361 taggaatgga ttctattcaa ttgattttaa tgattttgag aaaaagtgta aaaaatctaa
     3421 gatatttatt ttatgtaatc ctcacaatcc aactggtaga gtatggagtg agttagaact
     3481 tgttaagatg ataggaattt gtaagaataa tgatgtcaag ataatatcag atgatataca
     3541 catggatatt gtatatgaca atagaatgac acctatctta aatgttgcaa aggactattt
     3601 agattctgta ttcatttgta catcagcgtc taaatctttc aatataccag cattgactgg
     3661 gtcatatgtg attataccaa atgaaggtat tagaaataaa tttgaaaata tcactagata
     3721 ccgtgatttt gtaaattcgc cagcaattct agcaatatta gctacaatgg tctgttatga
     3781 tgactgcgaa tattggttag atgaactatt aaaatacctt aaagagaatc ttaaatatac
     3841 gattgattat ataaaagata atttagaacc attgaaattg gtcatgccag aaggctgtta
     3901 ctttgcttgg atagattttt ccgaacttaa aataagtggt gagaaattcc aaaaattatt
     3961 gatggatatt ggagaagttg ctattatgtc ggggtctgta tatggtgaag aaggtgagtt
     4021 ttatttaagg ttaaatgtgg catgttcaag agaaaaactt gaagatggtt taaataggat
     4081 taaaaaaact atggattata ttgcaaaaag aactttatag taggaaggga gatagttatg
     4141 ggatatttaa aaacaatggt tgatgttatg actactgaaa tgaatgccat aagatgttta
     4201 atagatgaag caggaataga atatgaaagt atagttagtg aaattgcaaa ttgtgaaggc
     4261 aaagtaattt ttatgggtgt aggaaaatct gcacatatag gtaagaaatt ggcagctaca
     4321 tttgctagta ctggtacacc tagctttttt gtacatgcaa cagaggcagt gcatggagat
     4381 ttaggaatga ttgaaagtaa ggatattaca attttaatat caaatagtgg aaattctatg
     4441 gaagtggtaa actgtataaa atatattaaa gcaataggtt ctaagacaat tgcatttact
     4501 tcaaacagaa attcagtact ggcaaaagag tgtgattatg ctttaatata tcctgcaaag
     4561 gatgaagcag accatttaaa tctagcacca acaacatcat ctacaattac tttggtttta
     4621 ggagattcta ttgcatgtgc attatctaag agtagtaatt ttggttcttc agatttttat
     4681 aagtaccatc caggaggaag tttaggtgag aagttaaaaa cagctaacaa tggataaaag
     4741 caaaaaggag agtagttttt atgttcaaaa tgtttaaaaa aaaatcaata aaatcaccca
     4801 tatcaggaaa agtaatagag ttatctaaaa tacaagatgg tgtattttct caaaaaatta
     4861 tgggagaggg tgtagctata gattctacag gagacattgt atatgctcca atcaatggaa
     4921 agatagtagt agtagcagag actaaacatg catttgtaat agaattagaa aatgggatgg
     4981 aacttcttat tcatgttggt ttagatactg taaatttaaa aggcgaaggt tttgaggcat
     5041 tggtgagtat gggagaacaa gtgaaggaag gaacaccaat gttgaaaatt aaccgtcctt
     5101 tgattgaatt aaagggtata tcacttatta ctccagttac aataactaat cattcagagt
     5161 acaatatgaa tacatgtaat gtaggcaata gcgttgaagg tgggaaagat actgtaattg
     5221 agtttaaata aagaattaaa atacaaggtt aatatttata aatacctata aacttatgtt
     5281 ttataagatt gattgtatgg atttattgta taaaaaagaa ctctttaatt ataaattaag
     5341 gagttttttt attttgtaaa tattgtttag atttatatag aaaaacactt agtaataaat
//
LOCUS       DAMJYN010000160         5396 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.166, whole genome shotgun sequence.
ACCESSION   DAMJYN010000160 DAMJYN010000000
VERSION     DAMJYN010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5396)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5396)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5396
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.166"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(541..1947)
                     /locus_tag="PC466_003566"
     CDS             complement(541..1947)
                     /locus_tag="PC466_003566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2770917.1"
                     /translation="MDSVKYILRRFIGSSILISLLFIVLNIAGFLLFSYMLFVSKYSD
                     NLDTSDSREIKSNLIMIEDNLILKDGKFILDDSSKEVLHKNKVWAMLIDNNGDRIWGF
                     DLPKEIPSHYTLTDVAKFSRFFLKDYPVYVWEHPNGILVTGYPKDKYTKFNLTYTIKE
                     IEQFPMLIIGMFLVNAIVTFLIALFIGLKMVKSIKPIITGIKLMSKGEPVLLQEKGIL
                     SDISKSINTVSKELQMKDEKLRKKEEARSNWIAGISHDIRTPLSMIIGYAGELEESSS
                     LSNREQEQVSIICNQGVKIRELVNDLNLVSKLEYNMQALNCDKIRVSAFLRELISEFI
                     NNNLDNDFYVELDILNEDIIIDADKKLLKRAISNLIQNSITHNQQGCNIRVTSKSDLD
                     FCYIIVEDDGKGMSQERINSLLKSQNGLSEAYAKGQNHGLGILIVAGIINAHRGKLDI
                     MSIDSQGLKTILKLPLIK"
     gene            complement(1992..2699)
                     /locus_tag="PC466_003567"
     CDS             complement(1992..2699)
                     /locus_tag="PC466_003567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2770918.1"
                     /translation="MESIKDKKILVVDDHKELLKMIDEILRKEGFSRVFLASSYEEAV
                     RVFRNVKPDCAILDVVLPDGDGFSIMRKIRETSKIPVIFLSARGEDEDRLIGLGLGAD
                     DYIVKPFLPKELTLRLVGILNRVYVPIEEEELPVFKLGDSVVVNLNSACVEKDGQEIS
                     LTAKEHSLLLKLYENKGRIVTNDSLCQAIWGDDMYGYENTLMVHVRRVREKIEKTPST
                     PKHLITVRGLGYKLMIN"
     gene            2861..3784
                     /locus_tag="PC466_003568"
     CDS             2861..3784
                     /locus_tag="PC466_003568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2770919.1"
                     /translation="MKHMEMIIRTQRLSKEYNKIFRVKDIDLRVPQGAVYGFLGPNGA
                     GKSTTLKMLLGLAKPTQGNINILGKELNEKNRISILKDIGSLIESPSYYGHLTGLENM
                     TIMQRLLDLPKKNVNEALKIVRLENQKNKKVNQYSLGMKQRLGIAMAIMKFPKLLILD
                     EPTNGLDPAGIEEIRELIKSLPEKYGMTVLISSHLLSEIDQIATSIGIINHGELVFQD
                     SIKELHNRGQSQIAIKAKNVVSAQKLLNTKGYMSLIQNGYLTIENLKDSDVAKINGML
                     VHSNIDVFRIEEHKKSLEDIFLELTGKAVTL"
     gene            3784..4545
                     /locus_tag="PC466_003569"
     CDS             3784..4545
                     /locus_tag="PC466_003569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2770920.1"
                     /translation="MKYLGLEFYKLKRKKIILMTFLFVAVEIMWCIVNSNRAITRNPD
                     MLGGFEYSYMLMSFASLNGLFFPILISIITSRISDIEHKGDTWKLLKSSVTSLNSIYL
                     SKFLCSAILVSIPILMQVLSIVLFGHFRGVIESISVSLLLKYTLGTILVSIAIIALHL
                     WIATVIPNQMIAITFGMIGSFIGLTSGLFYQGIRRLFIWSYYLELSPLSYAYDNVLGS
                     SVYRIDMNFSITILVFLIGMLIYYIGRNHLLKKEV"
     gene            4557..5294
                     /locus_tag="PC466_003570"
     CDS             4557..5294
                     /locus_tag="PC466_003570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2770921.1"
                     /translation="MLRKSVLGEILKLKNSFIWYVLLALPLISVLIGSGNFYLNQGIL
                     KKEWYSLWTQVSLFYGEFFFPILIAIFCAYICRLEHMNHNWNNVMTLPVNLKNIFLSK
                     LTVVSILTAITQVFFVIFYIVAGNMFGFSGSVPKELTGWIAKGWIISISIASIQLYMS
                     IKIRSFATPIGISLCLSLFGMGLIVAKPAVGIFFPYSMLGSAMGVIKQSALNVNDTIV
                     TICVAFITTIVFSEIANRNFRKNDVIS"
BASE COUNT         1865 a          834 c          694 g         2003 t
ORIGIN      
        1 atttctaaaa atactacaca aaaactctac tttagtagaa ctcaatggtg caaaatactt
       61 caatttaaaa catttatcgt actttaaata aataattata ataaaatata cttacaatag
      121 ttacatagaa gctattataa ctacacagaa caacgtataa ttaaaacttt tttaggatgt
      181 cattatattt tttcttaaaa ttaaaaaaca ctataccata attctatttt agtagaattt
      241 ttttgtcaat aataaaatta aatattaact aaaaaataaa aaaaatggaa ttatctaaag
      301 aatttaataa ccttacaata attccaaaat attatttcta tgaaaatttt gataccatga
      361 gtaactcagc cataagcgca taaagcacaa gttactcttt actttaataa aacttgacaa
      421 gaaaagaatt tatccttatt ctactctaat agagttattt tgtcaataaa gaataaaatt
      481 attttcaaaa tattttcatt cttcattctt cattcttatc tgttattatt ttataaaata
      541 tcacttaatt agaggtaatt ttagtattgt ttttagtccc tgactatcaa tactcataat
      601 atctaattta cctctatgtg cattaataat tccagctact atcaaaatac ctagaccatg
      661 attttgacct ttggcatatg cctcacttag tccattttgg ctctttaata aactattaat
      721 tctttcttga ctcatacctt ttccatcatc ttcaacaatt atatagcaaa aatctaaatc
      781 agacttagag gtaaccctta tattacatcc ttgttggtta tgagttatac tattttgtat
      841 taaattacta atagcccttt ttaataattt tttatctgca tctataataa tatcttcatt
      901 tagtatatca agttcaacat aaaagtcatt atccaaatta ttatttataa actcagaaat
      961 aagctctctc aaaaacgcag aaactctaat cttatcacaa ttcaatgctt gcatattata
     1021 ttcaagttta gatactaaat ttaggtcatt tactaattct ctgattttaa ccccttgatt
     1081 gcatataata gacacttgct cttgttctct atttgaaagg ctactgcttt cttcaagttc
     1141 tccagcatat ccaattatca ttgaaagtgg agttcttata tcatgagata ttcctgcaat
     1201 ccagttagac ctagcttcct ctttcttcct aagtttttca tctttcattt gcaactcttt
     1261 agatacagta ttaatagatt ttgaaatatc acttagtatt cctttttctt gtaaaagtac
     1321 tggttctcct tttgacataa gctttatgcc agtaataatt ggttttatag atttcaccat
     1381 ttttaaacct atgaatagag ctattaaaaa agtaactatt gcattaacca gaaacatacc
     1441 tattattaac ataggaaatt gttctatttc cttaatcgta taagtaaggt taaatttagt
     1501 gtatttgtcc tttggataac ctgttactaa tattccattt ggatgttccc atacatacac
     1561 aggatagtcc tttaaaaaga accttgaaaa ctttgctaca tctgtcaaag tataatgact
     1621 tggaatttct tttggtaaat caaatcccca tattctatct ccattgttat caattaacat
     1681 tgcccaaact ttatttttat gtagtacttc cttactagaa tcatctaaaa taaactttcc
     1741 atcttttaaa atcaaattat cttcaatcat aatcaagttt gattttattt ctctgctatc
     1801 acttgtatct aaattatcag agtatttaga tacaaatagc atatatgaaa acagaagaaa
     1861 acctgctata tttaatacaa taaaaagtaa tgaaatcaag atacttgaac ctataaatcg
     1921 cctcaatatg tactttacac tatccaaaat taaatcactc ctcttgattt cttttattct
     1981 aatatctaaa attaattaat catcaactta tatccaagac ctcttactgt aataagatgt
     2041 ttaggtgtag atggagtttt ttctatcttc tctctaaccc ttctaacatg aaccataagg
     2101 gtattttcat atccatacat atcatctccc caaatggctt gacatagtga atcattagta
     2161 acaattctcc ctttattttc atacaacttt aaaagcaacg aatgctcttt agctgttaaa
     2221 gaaatctctt gcccatcttt ctcaacacat gcactattta aattcacaac aacagaatct
     2281 cccagtttaa atactggcaa ctcctcttct tctataggca catatacacg atttaatata
     2341 cccacaagcc ttaaagtaag ttcctttggt aaaaatggct ttactatata atcgtcagcc
     2401 cctaatccca aaccaatcaa tctatcttca tcttcacctc ttgcagagag aaaaataact
     2461 ggtatcttag atgtctctct aatttttctc ataatagaga aaccatctcc atctggcaat
     2521 acaacatcta aaattgcaca atctggcttt acatttctaa ataccctaac agcttcttca
     2581 taacttgatg ctaaaaatac tctactaaat ccctcttttc ttaggatttc atctatcatt
     2641 tttaataatt ccttgtggtc atcaaccaca agtatttttt tatcttttat tgactccata
     2701 atcatcaccc tcctttagta taccatatac ccattttcac aactttgcct aaatagactt
     2761 ttaaggttat tgtaaggtaa acttcagcta actgaaatgt aaccaagtta ttatactgat
     2821 ataagttaaa agaatcaata agcacagatt aaaaaagggg atgaaacata tggaaatgat
     2881 aattagaaca caaagacttt caaaggaata caataaaata tttagagtaa aggatataga
     2941 cctaagagtt ccacaaggag ctgtatatgg ttttttgggt cctaatggag ctggaaaatc
     3001 taccactctt aaaatgcttc ttggacttgc taaacccaca caaggaaata ttaatatttt
     3061 aggtaaagag ttaaatgaaa aaaatagaat atcaatttta aaagatatag gttctttgat
     3121 agaatctcca tcatactatg gtcatcttac agggcttgaa aacatgacca taatgcaaag
     3181 actcttagat ttacctaaaa aaaatgtaaa tgaagcatta aaaattgtaa ggttagaaaa
     3241 tcaaaaaaat aaaaaagtta atcaatattc tttaggtatg aagcaacgtc ttggcattgc
     3301 tatggcaata atgaagtttc ccaaattatt aatacttgat gaacctacaa atggactcga
     3361 cccagcaggg attgaggaaa ttagagaatt aataaaatct ctaccagaaa aatacggcat
     3421 gactgttcta atctctagcc atcttttaag tgaaattgac caaattgcca catcaatagg
     3481 aataataaat catggcgaac tggtttttca agatagcata aaagaacttc ataatagagg
     3541 tcaaagtcag attgctatca aagctaagaa tgttgtatct gcacaaaagc tattaaatac
     3601 taaaggatat atgtcactta tacaaaatgg gtacttgact attgaaaatt taaaagactc
     3661 agatgtggct aaaataaatg gtatgcttgt ccattcaaat atagatgtat ttagaataga
     3721 agaacataaa aaaagcttgg aagatatatt cctagaactt actggtaagg cggtgacttt
     3781 ataatgaaat accttggtct agaattttat aaacttaaaa gaaagaagat tattctgatg
     3841 acctttttat ttgtagctgt tgaaataatg tggtgtatcg taaattcaaa tagggctatt
     3901 acacgtaatc cagatatgtt aggtggattt gaatattcct atatgcttat gagttttgca
     3961 agtttaaatg gtctattctt tcctatctta atatcaataa ttacatcacg cataagcgat
     4021 atagaacata aaggagatac atggaagctt ttaaaatctt ctgtgacatc tttaaatagt
     4081 atttatttat ccaaattttt atgttctgct attttggtat ctatacctat attgatgcaa
     4141 gtgttatcta ttgtgttgtt tggacatttt agaggggtta ttgagtcaat ttctgtatct
     4201 ttacttttaa aatacacatt aggaacaatt cttgtaagta ttgctatcat tgcactacac
     4261 ctatggattg caactgtaat tccaaatcaa atgattgcaa ttacatttgg catgattggt
     4321 agttttatag gtttgacatc aggtttgttt tatcaaggta ttcgtagatt gtttatatgg
     4381 tcttattacc tagagttatc acctttaagt tatgcttatg ataatgtttt aggttcatct
     4441 gtctatagaa ttgatatgaa tttttctatt acgattttag ttttcttaat tggaatgcta
     4501 atttattata ttggaagaaa tcatttatta aaaaaagaag tataggaggg atttaaatgt
     4561 taaggaagtc agttttggga gaaattctaa agttaaaaaa ttcttttata tggtatgtat
     4621 tattagcttt gccacttata agtgtgttga ttggttctgg taatttttat ctaaatcaag
     4681 gcatactcaa aaaagaatgg tacagcttat ggactcaagt tagtcttttt tatggggaat
     4741 ttttctttcc tatcttaatc gcaatctttt gtgcatatat ttgtaggctt gaacatatga
     4801 atcataattg gaataatgta atgacactgc cagttaattt aaaaaatatc tttttatcta
     4861 aacttacagt agtttcaata cttacagcta ttacacaagt tttctttgtt atcttttata
     4921 tagttgcagg aaatatgttt ggtttttctg gtagtgtacc taaagaattg actggttgga
     4981 ttgctaaagg ttggattatt tctatttcaa tagcttctat acaattatac atgtctataa
     5041 agattagaag ttttgcaact cctattggta ttagtctttg cctttctcta tttggtatgg
     5101 gattaatagt agcaaaacct gctgttggta tatttttccc ttattctatg ttaggtagtg
     5161 ctatgggggt tataaagcaa tctgctttaa atgttaatga cactatagtt acaatatgtg
     5221 ttgcatttat tactactata gtattttctg aaattgccaa tagaaatttt agaaagaatg
     5281 atgttatttc ttaatggtaa atgctagata ttttttggtt tgaaatttat attctttttg
     5341 gtttgaaatt tatatccctt ttatttaaaa atatatatct tttatttgaa ttttat
//
LOCUS       DAMJYN010000161         5347 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.167, whole genome shotgun sequence.
ACCESSION   DAMJYN010000161 DAMJYN010000000
VERSION     DAMJYN010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5347)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5347)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5347
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.167"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(204..1388)
                     /locus_tag="PC466_003571"
     CDS             complement(204..1388)
                     /locus_tag="PC466_003571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HDF2770922.1"
                     /translation="MLSKRLNFITPSYTIGISSKVKEMESNGVKVINLSIGEPDFNVP
                     NNAKSYGIDSLNKDYTKYDLVPGLKILREEICKKLIEENNCNYSIDEIVVSSGAKNSI
                     TNTLLALTDEGDEVLLPKPYWVSYPEMIKLVNAVPVFIDTKKENGFKLTKEELEKSIT
                     DKTKILVINNPSNPTGSVYTKDELIEIVDVCIQNKIYILADEIYEKICYTGEFTSIAS
                     LSEEAKDITITINGFSKSAAMTGLRLGYTASNKTIAKAMSSIQGHLISHPSLTAQYIA
                     YGALKDCSIDIDNMVKTYKSRRDLIKSKLDSIDNVGYVNPNGAFYIFIDLSKVSEKFE
                     YKDSFSIEFCNQFLEEYNVAVVPGIAFGMDKYIRISYACSENTFLSGLDKLKEFVYKI
                     MA"
     gene            1761..4112
                     /locus_tag="PC466_003572"
     CDS             1761..4112
                     /locus_tag="PC466_003572"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside triphosphate reductase"
                     /protein_id="HDF2770923.1"
                     /translation="MVEFVKKRDGRVIPFNEDRITRAIFLAATNVAEREGIVPDYKLS
                     EQLTQEVIKFLNHKYSESVPSVEDIQDSVVKVLIETGHAKTSEEYIIYRTERSRIRNS
                     KTRLMKAIEEITFEDAEDADIKRENANINGNTAMGTMLQYGSTVSKEFCKTHILKPEH
                     SFAHDNGDIHIHDMDFLNMGTLTCCQIDVKKLFNGGFSTGHGFLREPQDIISYGALAA
                     IAIQSNQNDQHGGQSIPFFDYGLAEGVYKTFKKFYIGNLAKALKLFKGIENNDVIKNI
                     VYNTEKETNQKVGLKRDELYLNLEKEKLIQTFDIDDELVNKMQNFAFEESYRETDKKT
                     YQSMEAFIHNLNTMHSRAGAQVPFSSVNFGTDTSEEGRMVTKNLLLSQERGLGNGETP
                     IFPILIFKVKEGINLNPEDPNYDLFKLSCRVSAKRLFPNFSFLDAPFNAKYYKKGEPD
                     TEATYMGCRTRVLSNVCGSETVSGRGNISFTTVNLPRLGIKHGIINNEKANLDGFFEE
                     LDEKINLIIEQLLERFEVQGNKKMKNFPFLMGQGVWKGSDDLVPEDTLKEVIKQGTLT
                     IGFIGLAECLIALIGKHHGESKEAQELGLKIVSHMRHKMDEATDKYKLNFSLMGTPAE
                     GLSGRFTKIDKKVYGEIKGITDKEYYTNSFHVPVYYNISAYDKIEIEAPYHELTNAGH
                     ITYVELDGDPSDNLEAFETVIKAMKDLGIGYGSINHPVDRDPICGFSGVITSNICPVC
                     GRNEDESDIKFERIRRITGYLVGTVDRFNNAKKAEVRDRVKHR"
     gene            4134..4673
                     /gene="nrdG"
                     /locus_tag="PC466_003573"
     CDS             4134..4673
                     /gene="nrdG"
                     /locus_tag="PC466_003573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HDF2770924.1"
                     /translation="MKIRMSSTISYDSIVDGPGLRMVIWTQGCIHNCKECHNPQTHDL
                     CGGFYMDTEEIINKVKSLKLQKGITLSGGEPFLQPEPLEEIAREAKINGLDVWSYTGF
                     TFEQLLDKKNRAYFKNLNLLKQIDILVDGKFIAEKKDISLKFRGSSNQRIIDVQKSLK
                     YKKVFLVEQYMKDDLSIAE"
BASE COUNT         2089 a          593 c          850 g         1815 t
ORIGIN      
        1 ttataataaa tttagaattt aacttatata gtttaatttg ataatttgat gaaaaaaata
       61 aaagacttac tgatttttaa atctataggt cttttatttt ttatctaaca tttaaattaa
      121 gttgttgaat atatcttata ttacttactt tatatattaa ttaccattaa tacattatat
      181 ctaattacta ttcatctaaa ttattatgcc attattttat atacaaattc ttttaatttg
      241 tctaatccag ataaaaaagt attttcactg caagcatagg atatacgaat atatttatcc
      301 ataccaaatg ctatgccagg aacaactgca acattatatt cttctaaaaa ttgattacaa
      361 aattctatag aaaaactatc tttatattca aatttctcag atactttaga aagatctata
      421 aatatataga atgcgccatt tggattcaca tatcctacat tatcaataga gtctagtttt
      481 gatttaatta aatctcttct tgatttatat gttttaacca tattgtctat gtcaattgag
      541 caatctttca aggctccata ggctatgtat tgtgctgtta gacttgggtg agatataaga
      601 tgtccttgta tagaactcat tgctttagca atcgttttat tagatgcagt atatcctaat
      661 cttaatccag tcattgcagc tgacttagaa aaaccattta tagttattgt tatatcttta
      721 gcttcttcgc ttaatgatgc aattgatgta aattcaccag tgtagcatat tttttcatat
      781 atttcatctg ctaaaatata tattttattt tgtatgcata catctactat ttctattaat
      841 tcatcttttg tataaacact accagtagga tttgaaggat tgtttattac aagaattttt
      901 gttttatctg ttatagattt ttcaagttct tcttttgtta acttaaatcc attttctttt
      961 ttagtatcaa taaaaactgg aacagcatta actaacttaa tcatttcagg ataactaacc
     1021 caataaggct ttggtaataa gacttcatct ccttcgtctg ttaaagctag taaagtattt
     1081 gttattgagt tttttgctcc acttgataca actatttcgt ctattgaata gttacagtta
     1141 ttttcttcaa taagtttttt acagatttcc tctctaagta tttttaatcc tggaactaaa
     1201 tcatatttag tgtaatcttt atttaaagaa tcaataccat aagattttgc gttattaggt
     1261 acattaaaat cgggttctcc tatactaaga tttattactt taactccatt actttccatt
     1321 tctttaactt tagaactaat acctattgtg taggatggtg ttataaagtt tagtcttttt
     1381 gataacataa aatgcctcct tttaaattat tatttatatt atacgacaaa tttaaagaat
     1441 ttacataagg aaatttgtag atatatacat taatatatat aatagcctac actttttgcc
     1501 taaaattagt gtaaaaaaaa gagaaaaaaa ttttaacttt caaagttgtt agaaacgcta
     1561 ctgttcaaaa tatccacata gtatttgcaa tgatttgcgc aagtttgact attatgtaca
     1621 aatttggtaa tcttaatata gcaattatta agataatccc tttaacttag ttgaagggga
     1681 tttttttaga cttaacatac tacatatagt ggtattggga ttaataaaat acaatatata
     1741 gtaacaggag gtttttttaa ttggttgaat tcgtaaaaaa aagagatgga agagtaattc
     1801 catttaatga agatagaata acaagagcta tatttttagc agcaacgaat gttgcagaaa
     1861 gagaaggaat agtacctgat tataaattat ctgagcaatt aactcaagaa gtaataaagt
     1921 ttttaaatca taaatactca gaatcagttc caagtgttga agatatacaa gattctgtag
     1981 ttaaggttct tatagaaact ggccatgcaa aaactagtga agaatatata atatacagaa
     2041 ctgaaagaag tagaataaga aattcaaaaa caagattgat gaaggcaata gaggaaatta
     2101 cctttgaaga tgcagaagat gctgatataa aaagagaaaa tgcaaatatt aatggtaata
     2161 cagcaatggg aactatgtta caatatggaa gcactgtatc taaagaattt tgtaaaacac
     2221 atatattaaa accagaacat tcttttgctc atgataatgg agatatacac atacatgata
     2281 tggatttttt aaatatggga acattaactt gttgtcaaat agatgttaaa aaactattca
     2341 atggtggatt ttcaacagga catggctttt taagagagcc acaagatata ataagttatg
     2401 gtgcattagc tgcaattgct atacaaagca atcaaaacga tcaacatgga ggtcaaagta
     2461 taccattttt cgattatgga ttggctgaag gtgtatataa gacatttaag aaattctaca
     2521 taggaaattt agctaaagca ttgaagttat ttaaaggaat tgaaaataat gatgtgataa
     2581 agaacatagt atataataca gagaaagaaa caaatcaaaa agttggtctt aagagagatg
     2641 aattgtatct aaacttagaa aaagagaaat taatacagac ttttgatata gatgatgaac
     2701 ttgtaaataa gatgcaaaac tttgcatttg aagaatcgta tagagaaact gataaaaaaa
     2761 catatcaatc tatggaagca tttatacaca atctaaatac aatgcactct agagcaggtg
     2821 cacaggtacc attttcaagt gtaaacttcg gaacagatac ttctgaagaa ggaagaatgg
     2881 taactaagaa tcttctatta tctcaagaaa gaggtttagg taatggagag acaccaattt
     2941 ttccaatttt aatatttaag gtcaaagaag gcataaattt aaatcctgaa gaccctaatt
     3001 atgatttatt taaattatca tgcagagtat cagctaaaag actatttcct aattttagtt
     3061 ttttagatgc gccttttaat gcaaaatatt ataaaaaagg tgaaccagat acagaggcta
     3121 catatatggg ttgtagaaca agagtactta gtaatgtgtg tggttcagaa acagttagtg
     3181 gtagaggaaa catatctttt actacagtaa atttaccaag attgggtata aaacatggta
     3241 ttataaataa tgaaaaggct aatttagatg gtttctttga agaattagat gagaagataa
     3301 acttaattat agaacaatta ttggagcgct ttgaggttca aggaaataaa aagatgaaga
     3361 attttccatt cttaatgggg caaggtgtat ggaaaggttc tgatgattta gtaccagaag
     3421 atacactaaa agaagtaata aaacaaggaa cattgacaat tggatttata ggtttagcag
     3481 agtgccttat tgctcttata ggtaaacatc atggagaaag taaagaagct caagaattag
     3541 gattaaaaat agtgtcacat atgagacata aaatggatga agcaacggac aaatataaat
     3601 taaatttctc cttaatgggt actccagcag aaggtctttc aggtaggttt actaaaatag
     3661 ataaaaaagt ttatggagaa attaaaggta tcacagataa agaatattat actaattcat
     3721 tccatgtacc agtttattac aatataagtg catatgataa aattgagata gaagctccat
     3781 accatgaatt gactaatgca ggtcatataa catatgtaga gttagatgga gatccatctg
     3841 ataatttaga ggcttttgaa actgttataa aagctatgaa agatttgggt ataggatatg
     3901 gaagtataaa tcatcctgta gatagagacc caatatgcgg tttttcaggt gtaataacaa
     3961 gtaatatatg ccctgtatgt ggaagaaatg aagatgaaag tgacatcaaa ttcgaaagaa
     4021 taagaagaat aacaggatac ttagttggta cagttgatag atttaataat gctaaaaaag
     4081 cagaagtaag agatagagta aaacatagat agttttattt gggggaataa gttatgaaaa
     4141 taagaatgtc atctactata agttatgaca gcatagttga tggaccagga ttaagaatgg
     4201 taatatggac tcaaggatgt attcataatt gtaaagagtg ccataatcct cagacacatg
     4261 atttatgtgg aggattttat atggatacag aagaaattat aaataaagtc aaatcattga
     4321 aattacaaaa aggcattacg ctatcaggag gagaaccatt tttacaacca gaaccattag
     4381 aagaaatagc aagagaagct aaaataaatg ggttagatgt atggtcatat actggattta
     4441 cgtttgaaca actgttagat aaaaaaaata gagcgtattt taaaaattta aatttactaa
     4501 agcaaattga tattttagtg gatggaaaat ttatagctga aaaaaaagat ataagcttaa
     4561 agtttagagg gtcatcaaat caaaggataa ttgatgttca aaaaagtttg aaatataaaa
     4621 aagtgttttt ggttgagcaa tatatgaagg atgatttatc tatagcagaa taaaatataa
     4681 ataaacagga ttaaatatat gcatatattt aatcctgttt attttcatat aatatttcaa
     4741 gtttgtataa tgtaacaatt aaaccaaaag actcattgta tatttgaaat taagtttttt
     4801 atagtttata ggtgttttat gtggattacg aatgatatag tatcgataca ttatttaatc
     4861 gattcttatt ccaagaaaca attaatttat agaaattctt aattgttaca atataaatat
     4921 ctagataagt tataagatac tgataaataa tttataaagt ttattaatct aatattgtgt
     4981 gtgaatgtta agtggtcaag tagtctaaaa aatgaaaaag atttaaaaaa gtgttttaac
     5041 taaacacata agtgttaaat tcatgtataa gtataggtta gatacataag aaataattat
     5101 gtaatatcta tctttgtaaa aaaatattaa attttgtaat ttgtggataa atatgtttat
     5161 aatgtggata atatttaatg taataagtta aagcaatatg aatcaactgt ttataatgtg
     5221 gataatatta taaatgtatg aataattgca gtatttaaaa acaaaaaaag ttaaaaaagt
     5281 tgttgactct aaaagaaaaa gttggtatag taatacttgt cctcaagaaa agggcaaaca
     5341 aataaag
//
LOCUS       DAMJYN010000162         5160 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.168, whole genome shotgun sequence.
ACCESSION   DAMJYN010000162 DAMJYN010000000
VERSION     DAMJYN010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5160)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5160)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5160
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.168"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            155..1048
                     /locus_tag="PC466_003574"
     CDS             155..1048
                     /locus_tag="PC466_003574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HDF2770925.1"
                     /translation="MKNKKFIVIILIISILIGVLVKEYSSREIKKDDINVSKYIKYAD
                     LASKNNAQVNWKYVASIVAVLNKNNLKNVKDSQIQEVSDLFVKNFSKNNKINKLSDIL
                     DELEFSNRQKRLVDNYIDNLKDYGIKPERLKSDTKYMKFIAEIKTEAIQNYKDYKILP
                     SITIAQAIIESSWGKSTLAKQYNNLFGIKADAYWKGKSVTLETKEHLDTIIDDKFRIY
                     DDKNESIKDHAKFLATNKRYKNNGVFDAKTYIYQAKALEKAGYSTAKDENGNSIYAAR
                     LIELIQQYNLQLIDSEIQSEV"
     gene            1096..3396
                     /locus_tag="PC466_003575"
     CDS             1096..3396
                     /locus_tag="PC466_003575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770926.1"
                     /translation="MKKIFSIFISCMVVVTTITGCSSGEVIKNTSPINSVKNLDFSFE
                     VKPEIFEVSVESGGSKEKISEPSKERKVSNFKKNKTEASWTYPDENIDINIKKEDSYL
                     DVNIKSNLEKETSFNWPKVEGESYILPLYEGKFIPSNDKYWKEYLNESTYNVIESFSM
                     QFFAVNKAKYSVIYIIENEFNNVIEFSSKDKINFTFKHEYPSINKNKEYGFKIYLTNK
                     NITDVAKTYKNYIVDKGEFKTLKEKSKENKNIEKLYGAPHIYFGDKSIITINDIEWNK
                     LKENLSDDLTNWMKELLSMKSGNSEFIKVINQIKTQDYIDKYQKNQIVQAFNEVMQMN
                     TFYNEKVFESKDREIKKVLDKGISKLSRVELIEFNKKLLKSKLEESVNDVATWAKYNT
                     TDVINDINKSGIKNAWIGFDDMEEGYISLEMVKRANELGYLVGPYDSYHSIHKPGEEK
                     WSTASFKDKSLYENATIENKKGEKETGFQGEGRKLNPTLSLPSVKERVQSILDEGYEF
                     NSWFIDCDATGEIYDDYSQNHITTQTQDLNARLERMSYIRDHANMVIGSEGGNDFSSS
                     TIAFAHGIETPAFAWVDKDMSKNKGSEYYVGKYYSPTGGVPEIFSKQIPVKERYKKIF
                     IDPIYSLPLFRLVYNDSVISSHQWLWGTLKIKDEVGSRMMKEVLYNTPPMYYIDRTEW
                     EKHKDEIISNNKVWSAFNKKAIKKEMTDFKFISEDRLVQMTEYGEDLKVLVNFSQKDI
                     KYNDEVIKANSLVIYDADSKVIYKPE"
     gene            3630..4121
                     /locus_tag="PC466_003576"
     CDS             3630..4121
                     /locus_tag="PC466_003576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3794 domain-containing protein"
                     /protein_id="HDF2770927.1"
                     /translation="MYENNKVIYNFERCEKLENALYLSQFNTYKNFKLTSKKTVINSL
                     DTSTYNMNIHSISLVDTMECISSEDEQMTGKKLILVGDIDTDVTLDYAGNKRNRNSSK
                     KNTFKLKIPFSTFIQMPRKIENKDKINLKYLIQDITSSILDDNLFISVTAIISYENSS
                     KIE"
     gene            4149..5096
                     /locus_tag="PC466_003577"
     CDS             4149..5096
                     /locus_tag="PC466_003577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770928.1"
                     /translation="MRITKTTFNDVFSNDANGSIIKVEKYVDKKCASVFEILTYTIIV
                     TNTSRYKTGNIFFKDYISKYIEFINNTVKVNGIIKRGLDPQQGFYIGRIDASCKKIIS
                     FKSVVLPNSAHRIIKNSANIYYYYKCNLDKFPTRISIESNRVYTNVNKIVFKQLNISN
                     TLKAPKNLRDILKVNVNSKIFDVKPMKNLINKGSNLKLCNSIVFGCIEVEIDYSCKNR
                     SNFKTVNKFNDIKKDKYYKNDIQNNNENINDCKKQISFGDNKVKKITKTFGFSCFICS
                     PVGIIYEDMKNINIKIEHTSINELNPEELFVNTSLLLYY"
BASE COUNT         2216 a          469 c          843 g         1632 t
ORIGIN      
        1 tgtgtgatag aaaactatat attataacaa tagtagtgcc tttaattaaa tatatttcat
       61 aaatcttcat aaaatcttca aaatttcgta aagaatatgt cacaaaagta aggtatatta
      121 tattcagcag atagtataag ggaggacaat atttatgaag aataaaaaat tcattgttat
      181 aatactgata atatcaattt taataggtgt attagtgaag gaatattcat ctagagagat
      241 aaaaaaggat gatataaatg tcagtaagta tataaaatat gctgatttag caagtaaaaa
      301 taatgcacaa gttaactgga agtatgtagc ttccattgtt gctgtgttaa ataaaaataa
      361 cttaaaaaac gttaaggatt cacagataca agaagtatca gatttatttg ttaagaattt
      421 ttctaaaaat aataaaataa ataagttaag tgatattttg gatgagttag aatttagtaa
      481 tagacaaaaa agattggttg ataattatat agacaatctt aaggattatg gtataaaacc
      541 agaaagattg aagtctgata caaaatatat gaagtttatt gctgaaatta aaacagaagc
      601 aatacaaaat tataaggatt ataaaatact tccatctata actattgcac aagctataat
      661 agaatctagc tggggcaagt caactttggc aaaacaatat aacaatctat ttggtataaa
      721 ggctgacgct tattggaaag gtaagtcagt gactttagaa acgaaagaac atttagatac
      781 aattatagat gataaattta gaatatatga tgataaaaat gaatctataa aagaccatgc
      841 aaaattttta gccacaaata aaaggtataa aaacaatggt gtatttgatg caaaaacgta
      901 tatatatcaa gctaaagcat tagaaaaggc aggttatagt actgcgaagg atgaaaatgg
      961 caatagtata tatgcagctc gtctaataga attaattcaa cagtataatc ttcaattaat
     1021 agacagcgaa attcaaagtg aagtgtaact tttatgtaac ataggagtga tatatttatc
     1081 gaggaggtgg tttttatgaa aaaaatattc tcgatattta taagttgtat ggttgttgta
     1141 actactatta ctggatgtag tagtggtgag gtgataaaaa atacatcacc tatcaatagt
     1201 gttaaaaatt tggattttag ttttgaggtg aaacctgaaa tatttgaggt atcagttgaa
     1261 tctggtggtt caaaagaaaa gatatctgaa ccctcaaaag aaaggaaagt atcaaatttt
     1321 aaaaagaata agacagaggc atcgtggacg tatcctgatg aaaatataga cataaatata
     1381 aaaaaagagg acagctattt agatgtaaat attaaatcta atttagaaaa agaaactagt
     1441 tttaattggc ccaaagttga aggggaaagt tatatactac cactttatga gggtaagttt
     1501 ataccaagta atgataagta ttggaaggag tatctaaatg agtcaactta taatgttata
     1561 gaatcttttt caatgcaatt ctttgcagta aacaaggcaa agtattctgt gatttatatt
     1621 atcgaaaatg aatttaacaa tgtaattgaa tttagttcta aagacaagat taattttaca
     1681 tttaaacatg aatatccaag tatcaataaa aataaggagt atgggtttaa aatatatttg
     1741 actaataaga atattacaga tgtagcaaaa acttataaaa attatatagt tgataaagga
     1801 gaatttaaaa cattaaaaga aaaatctaag gaaaataaaa atattgaaaa actttatgga
     1861 gcaccacata tttattttgg agataagtct atcatcacaa taaatgatat tgaatggaat
     1921 aaattaaaag aaaatttatc agatgatttg actaattgga tgaaagagct tttaagtatg
     1981 aagtctggca atagtgaatt tataaaagta attaatcaaa taaaaactca agattatata
     2041 gataaatatc aaaaaaatca aatagtacaa gcatttaatg aagttatgca gatgaatact
     2101 ttttataatg aaaaagtttt tgaaagcaaa gatagagaaa taaaaaaagt attagataaa
     2161 ggtatatcta aattaagtag ggtagaactt atagagttta ataagaaatt attgaaatca
     2221 aaattggaag agagcgtgaa tgatgttgct acatgggcaa aatataatac aactgatgta
     2281 attaatgata ttaataagtc tggtattaaa aatgcgtgga taggatttga tgatatggag
     2341 gaaggttata tatccttaga gatggttaaa agagctaatg agttaggtta tctcgtaggg
     2401 ccatatgatt cataccactc tatacacaaa ccaggggaag aaaagtggag tacagcatca
     2461 tttaaagata aatctctata tgaaaatgct accatagaaa ataaaaaagg tgaaaaagaa
     2521 actggatttc aaggagaagg aagaaaacta aatcctacat tgtctttacc aagtgtaaaa
     2581 gagagagtac aaagtatatt ggatgaagga tatgaattta attcttggtt tatagattgt
     2641 gatgctacag gagaaatcta tgatgattat tctcaaaatc atataacaac acaaacacaa
     2701 gatttaaatg ctagacttga aagaatgtca tatataagag accatgcaaa tatggtcata
     2761 ggttcagaag gtggaaatga tttttcaagt agtactatag catttgcaca tggtattgag
     2821 acaccagcat ttgcttgggt agataaagat atgagtaaga ataaaggcag tgaatattat
     2881 gttggtaaat actattctcc aacaggagga gtaccagaaa tattttcaaa gcagatacct
     2941 gtaaaagaaa ggtacaaaaa aatatttata gacccaattt actctctacc tttatttaga
     3001 ttagtttata atgattctgt gatatcttcc catcagtggt tatggggaac tttgaagatt
     3061 aaggatgaag ttggaagtag aatgatgaaa gaagtattat ataatacacc acctatgtat
     3121 tatatagata gaactgaatg ggaaaaacat aaagatgaaa taatctcaaa caataaagta
     3181 tggtcagcgt ttaataagaa agctattaaa aaagaaatga cagactttaa atttatttct
     3241 gaggatagac tagttcaaat gactgaatat ggagaagatt taaaggtatt agttaatttt
     3301 tctcaaaaag acattaagta caatgatgaa gtcataaaag caaattcttt ggtaatatat
     3361 gatgctgata gtaaagtcat atataaaccg gaataataga tttaatgaaa ataaagattg
     3421 tttaaatttc aagtaaaaaa taatataata ttcatttagt ttgtattaaa gtagtgacta
     3481 tattaatctg gataattagt atagtcacta ttatttatat tctttcctaa aagtaagtag
     3541 taactgaatc gtgaataatc aaaaatggta atttgaaata gtttttatga atagtattaa
     3601 tatatagata tagggagatt gatgtgatta tgtatgaaaa taataaggta atatataatt
     3661 ttgaaagatg tgaaaagcta gaaaatgctc tttatttatc tcaatttaat acatataaaa
     3721 actttaagtt aacttctaaa aaaactgtaa taaactcatt agatacatct acttataata
     3781 tgaatattca tagcataagt ctcgttgata ctatggaatg tatatcgtca gaagatgaac
     3841 aaatgacagg aaagaagttg attttagttg gcgatataga tactgatgta acattagatt
     3901 atgcaggcaa taaaagaaat agaaattcta gtaaaaaaaa tacatttaaa ttaaaaatac
     3961 cctttagtac atttatacaa atgcctagaa agatagaaaa taaagataaa attaatttaa
     4021 agtatcttat acaagatatt acttcatcta ttttagatga taatttattt attagtgtta
     4081 ctgcaattat aagttatgaa aatagttcca agatagagta atctttaaat tatagaaagg
     4141 tggatgcaat gagaataacg aaaactactt ttaatgatgt attttcaaat gatgcaaatg
     4201 gaagtattat aaaagtagaa aaatatgttg ataaaaaatg tgcatctgta tttgagattt
     4261 tgacctacac tattattgtt acaaatacaa gtaggtacaa aactggaaat atatttttca
     4321 aagattatat ttctaaatat atagagttta taaataatac tgtaaaagtt aatggcatta
     4381 taaaacgtgg attagaccca cagcaaggtt tttacatagg gagaatagat gcaagttgta
     4441 aaaaaataat atcttttaag agtgtagttt taccaaattc tgcacatagg attataaaga
     4501 atagtgctaa tatatactat tattataagt gtaatctaga taaattccca acaagaatat
     4561 caatagaaag taatagagtt tatactaatg taaataaaat tgtattcaaa caattgaata
     4621 taagtaatac tttaaaagct cctaaaaatc taagagatat attaaaagta aatgtaaata
     4681 gtaaaatatt tgatgttaaa cctatgaaaa atcttataaa caaaggtagt aatttgaaat
     4741 tatgtaactc gatagttttt gggtgtatag aagttgaaat agactatagt tgtaaaaata
     4801 ggagtaattt taaaacagta aataagttta atgatattaa aaaagataag tattataaaa
     4861 atgatataca aaataacaat gaaaatataa acgattgtaa aaagcaaata agttttggtg
     4921 ataataaggt aaaaaaaata acaaaaactt ttggattttc ttgtttcatt tgttctccag
     4981 ttggaattat ttatgaagat atgaaaaata taaatataaa aattgaacat acatcaataa
     5041 atgaattaaa tccagaagaa ttatttgtaa atacatcact tttattgtat tattaagtat
     5101 tttaaagcta aaacttaaac ttattaaaat agcatttggt taaaggaaaa tagatattga
//
LOCUS       DAMJYN010000163         5105 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.169, whole genome shotgun sequence.
ACCESSION   DAMJYN010000163 DAMJYN010000000
VERSION     DAMJYN010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5105)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5105)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5105
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.169"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            86..1969
                     /locus_tag="PC466_003578"
     CDS             86..1969
                     /locus_tag="PC466_003578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HDF2770929.1"
                     /translation="MFNKNKENITLSNQIKGTIQNSLTKEAILHIPMSNYAYGYDRET
                     LHIRLRTKKNEAKRVILRIGDQYVWDKGGAGGGNLNASGVGWSGGTNIVMSKEVETEL
                     FDYWIAKCKPLNKRSRYGFIIEGQEEKLLFTEKRIIELGNENDEKELCEIGNFFGYPY
                     LNYIDIPKVPNWVKDTVWYQIFPDRFANGDPSINPEGVDKWGAIPTRDNFTGGDLQGV
                     IEHLDYLSDLGINGIYFCPITIGKTNHRYDTVDYMEVDPTLGDKETLKKLIEEAHKRN
                     IKIMLDAVFNHIGYYSKQWQDVVQNKENSRYKNWFYIKDMSKIDTPIEQIDEKNIPYE
                     TFGCEKYMPKLNTENSEVIKYLLDVGKYWIQEFDIDAWRLDVSNEVDHVFWRKFREEV
                     KKVKPDIYILGEIWHGSLPWLMGDQFDSVMNYLMSEAMKKFFCTDEINAEEFKYMIND
                     VMVSYPIQVSEVIFNLLGSHDTTRILTYANGNIDRFKLAYMFMFVQTGCPCIYYGDEI
                     GMEGELSSISEGQRKCMEWNEEKWNKDIFDFMKKIIRLRKENKELRSISNEWVLADKE
                     NGTIILKKESISIIINNSSKNIILTLPDYLANKKVKDLYEEEIVDLKEELMLEKYKFI
                     ILK"
     gene            2193..2873
                     /gene="pgmB"
                     /locus_tag="PC466_003579"
     CDS             2193..2873
                     /gene="pgmB"
                     /locus_tag="PC466_003579"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HDF2770930.1"
                     /translation="MIEAFIFDLDGVITDTAYYHYMAWRKLAHKVGIDIDTKFNESLK
                     GISRMESLDRILEFGNKKYSFSEEEKVRMAEEKNNYYVSLIDEITSNDILPGIESLLI
                     DVKSNNIKIGLSSASKNAINVLNHLGISDKFDFIADAGKCKNNKPHPEIFLMSAKGLN
                     VNPQNCIGIEDASAGIDAINSANMFSVGVGNYENLKKANLVVDSTNQLKFEYIQEKYN
                     EYIVRRII"
     gene            2870..>5105
                     /locus_tag="PC466_003580"
     CDS             2870..>5105
                     /locus_tag="PC466_003580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_097546124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HDF2770931.1"
                     /translation="MKCLFSNVDEWKIIQDKIEIKENRLAESIMSIGNGYMGMRGNYE
                     ENYSGDTHKGSYIAGVWFPDKTRVGWWKNGYPEYFGKIPNSVNYIGVRIFIDDVELDL
                     AKCKVEDFYRELDMKNGILNRRFIVNINDKKFEVRVTRFLSISVKELAVIKYSIKSLN
                     SNTKIKFVPYLDSNIKNEDSNYEEKFWNGISSSSLEYKGSILSRTKENAFNTPVFTVG
                     SMMYIKTNGDVEAVSHESDYNYCENSITMDVLKNKVASIEKYVSITSTRDYKESELLR
                     KCEDILNIELSKSYDDILNEHTKLWNKRWESADVKINGDKSSQQGIRYNLFQLFSTYY
                     GEDSRLNIGPKGFTGEKYGGATYWDTEAFCVPVYLGVADKEVTRNLLEYRYNQLEQAK
                     DNAKKLGLKGALYPMVTFDGVECHNEWEITFEEIHRNGSIVYAIYNYTNYTGDYKYIK
                     EKGIDVIIEIARFWASRVHLSTKKDLYMIHGVTGPNEYENNINNNWYTNCIAKWCLDY
                     AVENILRLEKECNECIDRNNVTREEVEFWKIISNKMYLPYDEELQIIIQNDNFLDKEF
                     VEVKDLPKENFPLNQNWSWDKILRSCFIKQADVLQGIYYFGNRFTKEEKKRNFDFYEK
                     YTVHESSLSSSIYSIIASEIDNLEKAYELYSRTARLDLDNYNNDTNDGLHITSMSGSW
                     LSIVHGFAGMRTWNETLSFDPKLPKEWKNYSFNINYRDNIINVDVCSDLIKIENLKGK
                     PIKII"
BASE COUNT         2109 a          458 c          958 g         1580 t
ORIGIN      
        1 atatattttt attgtgatat aatagtaaaa tatattaacc tatctttaga ttatataaat
       61 tattataaag gagggaaatt ttaaaatgtt taataaaaat aaagaaaata taactttaag
      121 taatcaaatc aaaggaacaa ttcaaaatag tttaacaaaa gaagctatat tacatatacc
      181 aatgagcaat tatgcctatg gttatgatag agaaacacta catataagac ttagaactaa
      241 aaaaaatgaa gcgaaaagag taattttacg aataggagac caatatgtgt gggataaagg
      301 aggtgcagga ggaggaaatt taaatgcatc tggagttggt tggtctggtg gaacaaatat
      361 agtaatgagt aaagaagtag aaactgaatt atttgactat tggatagcta agtgtaagcc
      421 tttaaataaa cgctcacgat atggttttat aatagaaggt caagaagaaa aacttttatt
      481 tacagaaaaa agaataatag agttgggaaa tgaaaatgat gaaaaggaat tatgtgaaat
      541 aggtaatttt tttggatatc catatttaaa ttatatagat atacctaaag tgccaaattg
      601 ggtgaaagat actgtttggt atcagatatt tccagataga tttgcaaatg gtgacccgtc
      661 tataaaccca gaaggagtag ataaatgggg agctattcca accagagata attttacagg
      721 tggagattta caaggtgtga tagaacactt agattatttg agtgatttgg gaataaacgg
      781 aatttacttt tgccctatta caattggaaa aaccaatcat agatatgata cggtagatta
      841 tatggaggta gaccctacat taggagataa agagacttta aaaaaactaa tagaagaagc
      901 gcataagaga aatataaaaa taatgttgga tgctgttttt aatcatatag gatattattc
      961 taaacagtgg caagatgtag ttcaaaataa ggaaaattct cgatataaaa actggtttta
     1021 tataaaagat atgagtaaaa ttgatactcc aatagaacag atagatgaaa aaaatatacc
     1081 ttatgaaacc tttgggtgtg aaaaatatat gcctaaactt aatacagaaa attcagaagt
     1141 aataaaatat ttattggatg taggcaagta ctggatacag gaatttgata tagatgcgtg
     1201 gagattagat gtttcaaatg aagtagacca tgttttttgg agaaagttta gagaagaagt
     1261 caaaaaagta aaaccagaca tttatatatt gggagaaatt tggcatggta gtttaccatg
     1321 gctaatgggt gaccaatttg attcagttat gaattacttg atgtcagaag ccatgaaaaa
     1381 attcttttgt acagatgaga taaacgccga agaatttaag tatatgataa atgatgtaat
     1441 ggtaagttat ccaatacaag ttagtgaagt tatttttaat ttacttggaa gtcacgatac
     1501 tacaagaata ttgacttatg ctaatggaaa tattgataga tttaaacttg catatatgtt
     1561 tatgtttgta caaacaggat gtccttgtat atactatggt gatgaaatcg gaatggaagg
     1621 agaattaagt tcaatatctg aaggtcaaag aaaatgtatg gaatggaatg aagaaaaatg
     1681 gaataaggat atatttgatt ttatgaagaa gattattaga cttcgtaaag aaaataaaga
     1741 acttaggtct atatcaaatg aatgggtgtt agcagataag gaaaatggaa cgattatatt
     1801 gaaaaaagaa tctatttcta taataataaa taattcatct aaaaatataa ttttgacgtt
     1861 accagattat ttagcaaata aaaaagtaaa agatttatat gaagaagaaa tagttgattt
     1921 aaaagaagaa ctaatgttag agaaatacaa gttcattatt ttaaaataat acaaaaagta
     1981 tttattttag atttcatgtt aaattattat acagtttaaa caagtcttta taaaacataa
     2041 aaaaatatgg tttacaagtg agtgaattga aagtagattt taaattaaag actgagttag
     2101 agtagataat tttataaata atatcttaaa tacaagatag aaaataaatt gattattagt
     2161 ctaaaaattt cttgtagaaa gaggaaataa gaatgattga agcatttata tttgatttag
     2221 atggtgtaat tacagatact gcatattatc actatatggc ttggagaaaa ctagcccata
     2281 aagttgggat agatatagac acaaaattta atgaatcttt aaaaggcata agtagaatgg
     2341 agtcattgga caggatatta gaatttggaa ataagaaata ttcattttca gaagaagaaa
     2401 aagtgagaat ggctgaagaa aaaaataatt actatgtatc attgatagat gagataactt
     2461 caaatgatat tttgccaggc atagaaagct tgttaattga tgtaaaatct aataatataa
     2521 agataggtct atcttctgca agtaagaatg caataaatgt attaaatcat ttgggtataa
     2581 gtgacaaatt tgattttata gctgatgcag gaaaatgtaa aaacaataaa ccacatccag
     2641 agatatttct tatgtcagcg aaagggctta atgtaaatcc acaaaattgt atagggatag
     2701 aggatgcaag tgcaggtata gacgctataa actcagctaa tatgttttct gttggtgttg
     2761 gaaattatga aaacttaaaa aaagcaaatt tagttgtaga ttcaacaaat caattaaagt
     2821 ttgaatatat acaagaaaag tataatgagt atatagttag gagaattata tgaaatgttt
     2881 atttagtaat gtagatgagt ggaagattat acaagataag attgaaatca aagaaaatag
     2941 attagcagag tccataatga gtataggcaa tggatatatg ggtatgagag gaaactatga
     3001 ggaaaattat agtggagata cacacaaggg gtcttatata gctggagtat ggtttccaga
     3061 taaaactcgt gttggttggt ggaaaaatgg gtatccagaa tactttggta aaattcctaa
     3121 ttcagtcaac tatataggtg taagaatttt catagatgat gtagaattag atttagcaaa
     3181 atgtaaagta gaagattttt atagagaatt agatatgaaa aatggtattt taaatcgtag
     3241 gtttattgta aatataaatg ataaaaaatt tgaagttagg gttactaggt ttttaagtat
     3301 atctgttaag gaacttgcag taattaaata tagtataaaa tcattaaatt ctaatactaa
     3361 aataaaattt gtaccatatt tagattcaaa tataaaaaat gaagattcaa actatgagga
     3421 aaagttttgg aatggaattt cttcaagttc tttagaatat aaaggtagta ttctttctcg
     3481 aacaaaggag aatgcattta atacaccagt attcactgtg ggttcaatga tgtatattaa
     3541 gacaaatggt gatgtagaag ctgtatctca tgagagtgat tataattact gtgaaaattc
     3601 gataacaatg gatgttttaa aaaataaggt tgcaagtata gaaaaatatg tatctataac
     3661 ttcaactaga gattataagg aaagtgagct attaagaaaa tgtgaagaca ttttaaatat
     3721 agaactatct aaaagttatg atgatatatt aaatgaacat acaaagttat ggaataaaag
     3781 atgggaaagt gcagatgtaa aaataaatgg agataaaagt agccaacaag gtataagata
     3841 taatttattc caactatttt caacatatta tggagaagat tcgcgattaa atataggtcc
     3901 aaaaggattt actggtgaaa agtatggagg agctacttat tgggatacag aagcattttg
     3961 tgttccagta tatctaggtg tagcagataa ggaggtaact agaaatcttt tagaatatag
     4021 gtacaatcag ttagaacagg caaaggataa tgcaaaaaaa ctagggctta aaggtgcttt
     4081 atatccaatg gtaacatttg atggagtaga atgtcataat gaatgggaga taacatttga
     4141 ggaaatccac cgaaatggaa gtatagtata tgcaatatat aactatacaa attatacagg
     4201 tgactataaa tatataaaag aaaaaggaat agatgtaata atagaaatag ctagattttg
     4261 ggcaagtaga gttcatttgt ctacaaaaaa agatttgtat atgatacatg gagtaacagg
     4321 tccaaacgag tatgaaaaca atatcaataa taattggtat actaattgta tagctaaatg
     4381 gtgtttagat tatgctgtag aaaatatctt acgattagag aaagagtgta atgaatgtat
     4441 tgacagaaat aatgtgacta gggaagaagt tgagttttgg aaaataatat caaataaaat
     4501 gtatctgccg tatgatgagg aactacaaat aataattcaa aatgataatt ttttagataa
     4561 agaatttgta gaagtaaagg atttaccaaa agaaaatttt cctcttaatc aaaattggtc
     4621 ttgggataag attcttaggt cgtgttttat aaaacaagca gatgtattac agggaattta
     4681 ctattttgga aatagattta ctaaagaaga aaaaaagaga aattttgact tctatgaaaa
     4741 atatactgtc catgaatctt ctttatcttc tagtatttat tctattattg cctcagaaat
     4801 agataaccta gaaaaggctt atgaattata ctcaagaaca gctaggcttg atttagataa
     4861 ttacaataat gatacaaatg atggactgca cataacttca atgtctggtt catggctttc
     4921 cattgtacat ggatttgcag gcatgagaac atggaatgaa actctatctt ttgaccctaa
     4981 gttgccaaaa gagtggaaaa attattcttt caatataaat tatagagata atattattaa
     5041 tgtagatgta tgtagtgatt taattaaaat agaaaattta aaaggtaaac caataaaaat
     5101 tattg
//
LOCUS       DAMJYN010000164         4795 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.170, whole genome shotgun sequence.
ACCESSION   DAMJYN010000164 DAMJYN010000000
VERSION     DAMJYN010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4795)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4795)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4795
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.170"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            141..802
                     /locus_tag="PC466_003581"
                     /pseudo
     CDS             141..802
                     /locus_tag="PC466_003581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902002.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
     gene            complement(1021..2058)
                     /locus_tag="PC466_003582"
     CDS             complement(1021..2058)
                     /locus_tag="PC466_003582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HDF2770932.1"
                     /translation="MNKKLIKAKIFIWSILAISLSIVFISLLIGTIISHSFNFPFNTL
                     NPKYNYDNYIVAKNESFSDKINDINVDWISGEVRIKRSDSNKIKLIQKIPSNFSKKKL
                     AKIMVDGNSLSIYDNSTKKFFIGINLPKPTILELYLPNKLYDKITLYTTSADIYSTYI
                     RSNTVEANTISGAIGLSGNINKINLDTTSGHIDITKLNSKNATLKSTSGEIQLSGKID
                     VLNLETTNGNINLKDIYNKNLTCSSVSGKMNLSGVFSDIKAESTSSNIKINSSKMLSS
                     LYCETTSANVDLSIPDNPGFTLNFDKVSGVLDSDFELNRHSDLYTYKNGITNLYLSTT
                     NGNLTIIKNNH"
     gene            complement(2051..2737)
                     /locus_tag="PC466_003583"
     CDS             complement(2051..2737)
                     /locus_tag="PC466_003583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770933.1"
                     /translation="MLDKIRTYIDSSFTGVNETKKVKELKDELFENLKEKYNDQIQDG
                     KTEQEAYNSVISGIGDLSELIESVKEPYSLPSELIEEKKKRALRASIAVALFIISPFL
                     FVVSVVSFGIEPTIAILLMLILIALGVGLLVYNQMTRTNYALYNDNLSNKFKEFEDFE
                     ENYNHINPVYKSFMNAYWIIVVSIYLITSILFNIWSFSWILFIIGAAGVNIVKGIIQL
                     KGYKEEDKYE"
     gene            complement(2749..3069)
                     /locus_tag="PC466_003584"
     CDS             complement(2749..3069)
                     /locus_tag="PC466_003584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2770934.1"
                     /translation="MIIASDMIRGHTETIILKHLLEKDSYGYEINKSILEKTKGLYEL
                     KEATLYTAFRRLEQSGAITSYWGDEVTGARRKYYSITNIGKEKYIKSREEWNNTKALI
                     DILI"
     gene            3430..4770
                     /locus_tag="PC466_003585"
     CDS             3430..4770
                     /locus_tag="PC466_003585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HDF2770935.1"
                     /translation="MIKSSLFWNIFIAISFMIEWFLCKKMLDYTSEKRISNKKINFCM
                     VGIIVFADIIYFFDVPPNIRVIISMIITIAFYKISYDVGFIKSVLISLIYWMLLIATD
                     ALSISLTVWLNSINDMSSMGTGDIYRIESIILGKILLIVSLFLYRALKIKLNIEINKR
                     TLFYIVIPIVANIASFFVIFEYIFNPGSGSLIHNFQFVMISVVLLISSITLVLIAKKL
                     QQYNTLVVENNMIKNTLKYENEYYEDIEKKYLKTRLLSHDMKNHILCINAMIKKGIDV
                     TSYLNNLQVEIQSNDLLFNTGNFILDAILSEKKEVCDKNDIELKIGINFSCCEAVELV
                     DICHIFSNILDNAIEACNKIDSGNRVICVKGDVMQNFYLIRVENTKMNKIITKNGDIL
                     TDKKGSLHGLGIKSVKNSVNKYGGNVVIEYDDKKFVVKIAIPLRNVKKAVNHVI"
BASE COUNT         1766 a          532 c          715 g         1782 t
ORIGIN      
        1 taataacaat tcaaaataaa taacttatgt aagaaccgta ggaactacgg ggatagcctg
       61 tggagaatta gtaagacata tgttagtatg caaaattcta tgaagcagga accctgtgac
      121 tttagtcatg ggaggttcag attttggctg aagatgaaga aaataatcat ataaatattg
      181 agatgcaaag agcttttgag aacgattatt tggaaagagc tgaatattat cttagtcgtg
      241 tacatggtag aaagttagaa gaaggtaaag agtataaaga aattggaaaa actattggaa
      301 tacatatact aaatcatgta aaatataatc acatagaaga ttatgtaaat tgcctgagat
      361 taacaatgga cgagcatcca gatatttatt ctagtaaaac tgcattatat tttatagagc
      421 ttccaaaaat tcataaatct gactatatag taaatagaat tatgctatgg ggaaaactta
      481 ttgataatcc ttctagctca gatgtaagag ttatagctaa gaatgattct attattaaaa
      541 aagcacttga tagattaaaa gaattaggta gcaatgaaga atatttatta aatctgaaaa
      601 gaggtgctta tatcatgaat aaaagtagaa attttaaaga agagattgaa agagagacag
      661 caattagagt tgcaaaagaa aaagattata aaataattat aatgttgaaa aaaatggttt
      721 taaattagat gacatattga ataaatttaa tgattttgac ttaagtgaag atgagataaa
      781 agaagtatat gaaaataatt gatgataaat aaaaagtgaa cttatataag tttgctgaat
      841 ctgagcctgg aaatatttat gtgtattttt taatgaataa aaatttattt taaaaacaat
      901 aattagaggt acagttaatt atatttttat gatactgtac ttctagtttt ttctattgta
      961 gatttattat ttactaataa atctacaata gaagtgcttt tgttgtaaga atcattttat
     1021 ctaatgattg ttttttataa tagttaaatt tccatttgta gtgcttaaat ataaatttgt
     1081 aataccattt ttataagtgt ataaatcact atgacgattc aactcaaagt cactgtccaa
     1141 aacaccagaa accttatcaa aatttaaagt gaaacctgga ttatcaggaa tagacaaatc
     1201 gacattggca gaagtagttt cacagtacag agaagacaac attttgctag aattgatttt
     1261 tatattactg ctagttgact cagctttaat gtcagaaaaa actccagata agttcatttt
     1321 tccagaaact gaactacaag taagattttt attgtatata tcttttaaat ttatattgcc
     1381 attagttgtt tctaagttta aaacatcaat tttcccagaa agctgtattt caccagatgt
     1441 tgatttgagt gtagcatttt tactatttag ttttgttata tcaatgtgac cactagttgt
     1501 gtctaaattt attttattaa tattaccaga gagacctatt gcacctgaaa ttgtgttagc
     1561 ttcaactgta ttacttctta tgtaagtgct atatatatct gctgaagtag tatataaggt
     1621 tattttatca taaagcttat tgggcaaata tagttcaagt attgttggtt ttggaagatt
     1681 aattccaatg aagaattttt tagttgaatt atcatatata gaaagagaat ttccgtcaac
     1741 cattattttt gctagttttt tctttgagaa attactaggg attttttgaa ttaatttgat
     1801 tttattagaa tcacttctct taattctaac ttcacctgaa atccaatcaa cattaatgtc
     1861 atttatttta tctgaaaaac tttcattttt agccactata tagttatcat aattgtattt
     1921 aggattaaga gtattaaaag ggaaattaaa agaatgtgaa attatagttc ctataaggag
     1981 tgagataaat acaatagaaa gtgatattgc caggatactc cagatgaaaa tctttgcctt
     2041 tataagcttt ttattcatat ttatcctcct ccttgtagcc ttttagttgt ataattcctt
     2101 tgacaatgtt gacaccagca gcacctatta taaatagtat ccacgaaaag gaccaaatat
     2161 taaatagtat gcttgtgatt agatatatag aaactactat aatccaatat gcattcataa
     2221 atgatttata aactggattt atatgattat aattttcctc aaaatcctca aattctttga
     2281 atttatttga taaattatca ttgtatagag catagtttgt ccttgtcatt tgattataga
     2341 ctaataaacc tactccaagt gctattaata tgagcattaa aagaatagct atagttggtt
     2401 ctatgccaaa acttacaact gagactacaa ataggaaagg gcttattata aaaagagcaa
     2461 ctgctattga tgctcttaag gctcttttct ttttttcttc aattaattca gaaggtagag
     2521 aatatggttc cttaacactt tcaattaact cagataaatc accaattcct gagattactg
     2581 agttatatgc ttcttgttct gttttaccat cttgtatttg gtcgttatac ttttctttta
     2641 gattttcaaa taattcatct ttaagttctt tgactttttt tgtctcatta actcctgtaa
     2701 agctactgtc aatataagta cgtattttgt ctaacatatt ttcacctcct aaattaatat
     2761 atctatcaat gcttttgtat tattccattc ttcacggctt tttatatatt tctctttacc
     2821 tatgtttgtt attgaataat actttcttct agctccagta acttcatcac cccaataaga
     2881 ggttattgca ccagattgtt caagtctacg aaatgctgta tacaaagtag cttctttcaa
     2941 ctcatacaat cctttggttt tttcaagtat agatttatta atctcataac cataactgtc
     3001 tttttcaagt aaatgtttta agataattgt ttctgtatga cctcttatca tgtcagatgc
     3061 gattatcatg aaaatcacct ccaattaaat atataatact ttgatatact tcgcctgtca
     3121 aggtatatca tgagaaaaga cattttattg taatatttat aaggttttat atagaaataa
     3181 tgtaaaaact ttataaataa tatattttat acctagttat agataacttt atatagttat
     3241 tattaaaaaa agcaataaaa agtttaattc aatttagcaa atttagtgat ataattaaaa
     3301 aagaaaagaa atatggactt atttggaata attttgacaa tctatttact acacgtgtag
     3361 agtcgtatat aattaaatta tacataaaat ataaaaaaat aatttagtaa tacgttagga
     3421 gaaagtatta tgataaagtc aagcttattt tggaatattt tcattgcgat atcctttatg
     3481 atagaatggt ttctttgtaa gaaaatgcta gattatacaa gtgagaaaag gatttctaac
     3541 aaaaaaataa acttttgtat ggtaggtatt attgtttttg ctgacataat atattttttt
     3601 gatgtacctc caaatataag agtaattata tctatgataa ttactattgc attttataaa
     3661 atctcatatg atgtgggatt tataaagtct gtattaatat ccttaattta ttggatgtta
     3721 ctaatcgcca cagatgcttt gagtatatct ttaacagttt ggcttaattc tataaatgac
     3781 atgagtagta tggggacggg agatatatac agaattgagt ctataatatt gggaaagata
     3841 cttttgattg tgtctttgtt tttatataga gccttaaaga taaaacttaa tatagaaata
     3901 aataaaagga cattatttta tatagttatt cctatagtcg ctaatatagc atcttttttt
     3961 gtaatttttg aatacatatt taatccaggg tctggtagct taatacataa tttccaattc
     4021 gttatgattt ctgttgtatt gcttatatca agtatcactt tagttttaat tgctaaaaaa
     4081 ttacagcaat ataatacttt agttgtagaa aacaatatga ttaaaaatac tttgaagtat
     4141 gaaaatgagt attatgaaga tatagaaaag aaatatttaa aaactagatt actaagtcat
     4201 gatatgaaaa atcacatact gtgtataaat gctatgatta aaaaaggtat tgatgttact
     4261 tcttatttaa ataatttgca ggtagaaatt cagagtaatg acttgttatt taatactggt
     4321 aattttatat tagatgctat attaagtgaa aagaaagaag tttgtgataa gaatgatata
     4381 gaactaaaaa taggaataaa ttttagttgt tgtgaagctg ttgaattagt agatatatgt
     4441 catatatttt caaatatttt agacaatgca attgaggcat gtaataaaat tgatagtgga
     4501 aatagagtta tttgtgttaa aggtgatgtt atgcaaaatt tttatttaat aagagttgaa
     4561 aatactaaga tgaataagat tattactaaa aatggagata ttttgacaga caaaaaaggt
     4621 tctcttcatg gacttggaat aaaaagtgta aaaaactctg taaataagta tggtggtaat
     4681 gttgtaattg aatatgatga taaaaaattt gtagttaaaa ttgctattcc acttagaaat
     4741 gtgaagaaag cagttaatca tgtgatttaa atgtatataa atttgatgtg tagaa
//
LOCUS       DAMJYN010000165         4794 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.171, whole genome shotgun sequence.
ACCESSION   DAMJYN010000165 DAMJYN010000000
VERSION     DAMJYN010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4794)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4794)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4794
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.171"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            25..423
                     /locus_tag="PC466_003586"
     CDS             25..423
                     /locus_tag="PC466_003586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDF2770936.1"
                     /translation="MIKKIEHVVITNNNIENYINFYKKFGFSSKEMSEKYKLKARNVK
                     INLNIKGYKFLPYVKNLKASRDNLCFKINTNIDEPKKYLEQNEIQIKRGIVECTGVFG
                     NMKSIYLKKTNGNLIELSNHRITESKPWKI"
     gene            411..1349
                     /locus_tag="PC466_003587"
     CDS             411..1349
                     /locus_tag="PC466_003587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HDF2770937.1"
                     /translation="MENLILSINVVLPLFLTMSLGYVLKKLGLFDTHTLNKMNNVCFK
                     SFLPLLLFFNIYNTDLDGSLNFKLMAVAVIIIFSIFLILVFIIPKIEKDNKTRGALIQ
                     GVFRSNFVIFGIPVTISLFGDKSIGVTSLLIAVIVPMFNVLSVVILEIFRGGKVNIRH
                     MIKSVLTNPLIIASFIGLTMLILNINIPTFLHKTIGDISKIATPLSLIILGGSFSFSA
                     IKGHIKTIILGVCGKLILVPSIFLPISIFLGFRNVELTSLMIMLSAPTAVSSFTMAQQ
                     MDSDSELAGQIVVFTSGFSIITVFLIIFILKQNNLI"
     gene            complement(1733..1957)
                     /gene="secG"
                     /locus_tag="PC466_003588"
     CDS             complement(1733..1957)
                     /gene="secG"
                     /locus_tag="PC466_003588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HDF2770938.1"
                     /translation="MSNILMGVQVVLGILLVISIMPQDSKNALPSEFGGEGSQAYFKP
                     KGKQAFLARVTKITAVLFFINALALLIVKK"
     gene            complement(2075..2581)
                     /locus_tag="PC466_003589"
     CDS             complement(2075..2581)
                     /locus_tag="PC466_003589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2770939.1"
                     /translation="MNLEIIRATSENAIEMGFIHSCSWRKAYKGIIPDKIIDEFTSEK
                     RAEVFQSVIPKAEEEYYLFKVNGIPAGFASLNRSQEDNAPKCVGEIYSIYFHPDFWGT
                     SVTKKGLQFCIDRLSNLGYSYITIWVLKDNTRAINFYKKNGFTCDDFEKEIHIGKKLL
                     EVRYSKKI"
     gene            2666..3094
                     /locus_tag="PC466_003590"
     CDS             2666..3094
                     /locus_tag="PC466_003590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HDF2770940.1"
                     /translation="MNPVKELNNLWHIVSMQMKTEMCSGKYPTIHGISLVELSILEIV
                     EQYPNSMMKEISEILELPKSTLTSAVKRLELKKFIKKNPCIKDKRRYNLVLTELGLKA
                     QQEHRDIEIIVFRNLLHQLDKDEIETFIRIFSKAVNKSKK"
     gene            complement(3214..4506)
                     /gene="eno"
                     /locus_tag="PC466_003591"
     CDS             complement(3214..4506)
                     /gene="eno"
                     /locus_tag="PC466_003591"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HDF2770941.1"
                     /translation="MSVIELVYAREVLDSRGNPTVEVEVVLEDGAMGRAIVPSGASTG
                     AFEAVELRDGDKGRYLGKGVETAVANVNEIIAPEIEGMDAFDQPAIDAIMIELDGTPN
                     KGKLGANAILGVSMAVARAAADEIGLPLFQYLGGVNAKQLPVPMMNILNGGEHADNNV
                     DVQEFMILPVGACCFKEGLRMGAEVFHSLKKVLGEKGLACGVGDEGGFAPNLGSNREA
                     LELIVEAITKAGYKPGEDVMLGLDVAATEMYNKETKKYVLAGEGKELTAAEMVALYED
                     WSNNFPIITIEDGLDEEDWDGWKLLTERLGNKLQLVGDDLFVTNTERLEKGIENGVAN
                     SILVKVNQIGTITETLDAIEMAKRAGYTAVISHRSGETEDSTIADLAVAVNAGQIKTG
                     APSRTDRVAKYNQLLRIEEMVGEQARYCGLKSFYNLKK"
BASE COUNT         1651 a          764 c          576 g         1803 t
ORIGIN      
        1 tatataaaat cttaaggagt tgccatgata aaaaaaatag agcatgtggt cattactaat
       61 aataatatag aaaattatat caatttttat aaaaaatttg gtttttcatc taaagaaatg
      121 agcgaaaagt ataaacttaa ggctagaaat gttaagataa atcttaacat aaaaggttat
      181 aaatttttac cttatgttaa aaatttaaaa gcaagtagag ataacttatg ttttaaaata
      241 aacacaaata ttgatgagcc aaaaaaatac ttagaacaaa atgagattca aattaagcga
      301 ggaattgtag aatgtacagg tgtctttggt aatatgaaat ctatttattt gaaaaaaact
      361 aatggaaatt taattgaatt atcaaatcat agaatcacgg agagtaaacc ttggaaaatt
      421 taatcctatc aataaatgtt gttcttcctt tgtttctcac aatgtcactt ggatatgttc
      481 taaaaaaatt aggtctattt gatactcata ctttaaataa aatgaataat gtctgcttca
      541 agtctttctt gccattatta ttatttttta atatatacaa tacagattta gatggttctc
      601 ttaattttaa gcttatggct gtagctgtta taattatttt ttcaatcttc ttaatcttag
      661 tctttattat tcctaaaatt gaaaaagata ataagacaag gggtgcatta atacaaggtg
      721 tatttcgtag caatttcgtt atatttggta ttcctgtgac aatttcacta tttggcgata
      781 agagtattgg agtcacatct ttattaattg cagttattgt acctatgttt aatgtattat
      841 ctgttgtaat tcttgaaatt tttagaggtg gcaaagtaaa tataagacat atgattaaaa
      901 gcgtcttaac aaatccactc ataatcgcct cttttatagg attgacaatg ctaattttaa
      961 atattaatat acctacattt ttacacaaaa ctattggtga tatttctaaa atagctactc
     1021 ctttatcact tataattcta ggcggatctt ttagtttttc tgctataaag gggcatataa
     1081 aaaccattat attgggcgta tgtggaaaac ttatacttgt accttctata tttttaccaa
     1141 ttagcatttt tcttggattt agaaatgtag aattaacttc acttatgata atgttatctg
     1201 ctccaactgc agtttcttca tttacaatgg cacaacagat ggattctgac agtgaattag
     1261 ctggacaaat tgtagtattt acttctggat tttctataat tacagtattt ttaataatat
     1321 ttattttaaa gcagaataat cttatttaat gatatttgat aacacaaatt ggtattatga
     1381 gaaacatata taaaattgat ttaattgcgt aaaaacatat tattatacta tttttactat
     1441 ataatataac tttgtgtata ttatctcatt aaacatggtg aaagtagtgt tgctatatat
     1501 tttttagttt gaaaaaaata tataaatata aacaatatat aaatacaaat aataaatgcc
     1561 aacaaatagt caatctataa aataaaaact ggactaatca tataaaatca ttagtccagc
     1621 ttttatttta cgtacttttt atgttgatgt acttttatta aaaactaaat ttaattttta
     1681 aatatctagc aaatgcacta attaaataat ggccagttat tcaacaatat cactacttct
     1741 taactataag taatgccaat gcatttataa aaaataatac tgctgttatc tttgtaactc
     1801 tagcaagaaa tgcttgtttt ccttttggtt taaagtaagc ttgacttcct tctccaccaa
     1861 attctgaagg taaagcattt tttgaatctt gaggcattat gctaattact agtaaaatcc
     1921 ctagcactac ttgcacaccc attaaaatgt tgctcattat tgcccctcct atctatttat
     1981 tacttaaatt tcattactct ttagtgtatc acaataatat agtcatttca agactattga
     2041 agtataaata acaaacaaaa ataatatgca attactatat cttttttgaa taacgtactt
     2101 ctaataattt ttttccaata tgtatctctt tctcaaaatc atcacaagta aaaccatttt
     2161 ttttatagaa atttatagct ctagtattgt cttttagaac ccatatcgtt atatatgaat
     2221 atcctaaatt gcttaatcta tcaatgcaaa attgtaatcc tttttttgtc acagatgttc
     2281 cccaaaaatc gggatggaaa tatatagaat atatttctcc aacacatttt ggagcattat
     2341 cctcttgact tctatttaat gaagcaaaac cagcaggtat accattcact ttaaaaagat
     2401 aatattcctc ttcagctttt ggaataacac tttgaaaaac ttctgctctt ttctcagaag
     2461 tgaattcatc tattatctta tctggaataa ttcctttata cgcttttctc cacgaacaag
     2521 aatgtataaa acccatttct atagcatttt cacttgtagc tcgtataatc tctaaattca
     2581 taaaaacacc atcctattga caaattaata cgattatcgt actatattag tgcgataatt
     2641 gtatcatata tggaggtaaa agtcaatgaa tcctgtaaaa gagctaaaca acctgtggca
     2701 tattgttagt atgcagatga aaacagaaat gtgtagtggt aagtatccta ctattcatgg
     2761 tatttcttta gtagaattaa gtattttaga aatagttgaa cagtatccca atagtatgat
     2821 gaaagaaatt agtgaaattt tagaattgcc aaaaagcaca ttaacaagtg ctgtaaaacg
     2881 tcttgaatta aaaaaattta ttaaaaagaa tccctgtatt aaagacaaaa ggaggtataa
     2941 cttagtctta actgaattag gtttaaaggc tcaacaagaa catagagaca tagaaataat
     3001 tgtatttaga aatctcttac atcaattaga taaagatgaa atagaaactt ttattcgtat
     3061 tttttctaaa gctgtgaata aaagtaagaa atgaaatata aaaaaaggat aagtgaattg
     3121 aaaaatcaac tatcacttat cccttataag ataaattttt atcttttatg ttatcttttt
     3181 aatctttaat gccatatttt taatcttcaa taactatttt tttaaattat agaaagattt
     3241 taatccacag tatctagctt gttctccaac catttcttct attcttaata attggttgta
     3301 cttagcaact ctatcagttc ttgatggagc accagttttt atttgaccag catttactgc
     3361 aacagctaaa tctgctatag tagaatcttc agtttctcct gatctgtgag atataacagc
     3421 agtatatcct gctctcttag ccatttctat agcatctaaa gtttcagtta ttgtacctat
     3481 ttgattaact ttaactaata tagagttagc tactccattt tcaattcctt tttctaatct
     3541 ctctgtgtta gtaacaaata agtcgtcacc aactaattgt aatttatttc ctaatctttc
     3601 agttaataac ttccatccgt cccaatcttc ttcgtctaaa ccatcttcta tagttattat
     3661 tgggaagttg tttgaccaat cttcatataa agcaaccatt tcagcagcag ttaactcttt
     3721 tccttctcct gctaaaacgt attttttagt ttctttgttg tacatttctg tagcagcaac
     3781 gtcaagtcct aacataacat cttcacctgg cttatatcca gcttttgtta tagcttcaac
     3841 tattaattct aaagcttctc tgtttgaacc taagtttgga gcaaatccac cttcgtcacc
     3901 aacaccacaa gctaatcctt tttctcctaa aactttcttt aatgaatgga atacttctgc
     3961 tcccattctt aaaccttctt taaagcaaca agctcctact ggtaatatca tgaactcttg
     4021 aacatcaacg ttattatcag catgctctcc accgtttaat atgttcatca ttggaacagg
     4081 taattgttta gcatttactc cacctaaata ttggaataat ggtaaaccta tttcatcagc
     4141 agctgctcta gctactgcca ttgaaacacc taatatagca ttagctccta atttaccttt
     4201 gtttggagtt ccatctaatt ctatcatgat tgcatctata gctggttggt caaatgcatc
     4261 cattccttct atttcaggtg ctattatttc atttacgtta gcaacagctg tttctacacc
     4321 ttttcctaag tatcttccct tatctccatc tcttaattca acagcttcaa aagctcctgt
     4381 agatgctcct gatggaacta ttgctcttcc cattgctcca tcttctaata ctacttcaac
     4441 ttctacagtt ggatttcctc ttgagtctaa tacttctcta gcatatacta attcaataac
     4501 tgacatttgt atatctccct tcgattttct attagttaaa ttttcattta ctgtaaacat
     4561 ccgtctacta ttttaatcta ctttctatat tatagtacat aaagttgctt ttgaaaatta
     4621 ggtacaaatt tatttgatgg gtaaatttgt aaaagttcct atttttattt tattttttat
     4681 aatattttaa tttatataat ataaaaaaac ttgtctaaaa tccaaaacca atcttaaata
     4741 cacaaatatt ataactagat ttaaaacatt aaacataaaa tgtacaacta atga
//
LOCUS       DAMJYN010000166         4728 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.172, whole genome shotgun sequence.
ACCESSION   DAMJYN010000166 DAMJYN010000000
VERSION     DAMJYN010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4728)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4728)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4728
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.172"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            205..1356
                     /locus_tag="PC466_003592"
     CDS             205..1356
                     /locus_tag="PC466_003592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HDF2770942.1"
                     /translation="MEIYLDNSATTKPYQEVIDKMVYALNTEYGNPSSVHRKGVEVEK
                     AIKEVRQDIAKSLGAKEKEIYFTSGGTECNNTIIRGITSLNKKRKNHIISTNIEHPSV
                     LNTLKDLEEDGFEVTYLEVGKDGKINIEDLKNAIKSTTCLVSMMHVNNEIGTIQPIGE
                     VGKYLKGLKEKIYFHVDAIQSYGKINFRPSKYNIDFMSVSAHKFHGPKGIGFMYIKEN
                     NRLKPMLTGGGQEIGIRSGTENVPGIYGLGEAVRILNKDLDVVISKVNNLKNILKNEI
                     IDNIEDIKINSPEDGVCHILNVSFRGTKGEVLLHYLEQKGIYVSTGSACSSKKKGSYV
                     LNAIGLTNEEINGTIRFSLSDMNTEEEMLEAVKVLKESICDLRSIMKRK"
     gene            1402..2577
                     /gene="thiI"
                     /locus_tag="PC466_003593"
     CDS             1402..2577
                     /gene="thiI"
                     /locus_tag="PC466_003593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HDF2770943.1"
                     /translation="MVYNILIVKYGEIGVKGKNRYIFENRLIRNIRNMLKPIGRFNVY
                     KEYGRIYVDLEDYDYEEVIEEVRKVFGIVGVCPGVRAKKDYDTLKEIALKMLEEKIEA
                     GYKTFKVESRRGDKSFGLTSQEMSMDIGGYLLSKVGDRINVDVRNPEVKIKCEYREFH
                     TMVYSDTIPGYGGLPLGTNGRAMSLLSGGIDSPVATWMVAKRGMEVEAVHFHSYPFTS
                     ERSQEKVKDLAKILAKYCGRVRLHKVNILEIQKAIGENCNEEEATILSRRFMMRIAQR
                     LSEKRHCDALITGESIGQVASQTIQGLTCTNAVVDLPVFRPLIAMDKSDIVDIAKKIG
                     TFETSIVPEEDCCSVFSPRKPVTKPRLEKIEKSETALDIEKLVQDAIDKIEVEDIEF"
     gene            2733..3536
                     /locus_tag="PC466_003594"
     CDS             2733..3536
                     /locus_tag="PC466_003594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HDF2770944.1"
                     /translation="MNKKGFTLIELLVVISIIGILVIVAVPALFRNIEKSKAVTCLSN
                     RENIKTQIVIAMAEESSKDKNEVIKEVLENKDGKYFETEPKCKSGGIYSATFDDGYDG
                     ITGIESIAKVYVTCTKHPDGIEMARDIHQSMKDLIASFAQDPSIIPGASKGNDDFRKY
                     LLDNKYKNGWPTIPDEFKAKYGLSKDTLYIQPYAYNPTKSDATVVVFANNKTGGNWYT
                     SLVYDYDEGRWYKGKNGISVAGRSWDVDTDSVKSVKTEIHSKEGWGPLN"
     gene            3779..4420
                     /locus_tag="PC466_003595"
     CDS             3779..4420
                     /locus_tag="PC466_003595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase"
                     /protein_id="HDF2770945.1"
                     /translation="MNNNFQDNQTINLIQSRRSIRKFTTEQISDEQVNTLLHCAFAAP
                     SGCNKQPWHITVVQDQKLLKEISDDTLSRIHEVSNVEINKNFKLFYGAPTVLFISYDE
                     SSSWAPYDIGILTGNITTAAQALGLGSCIIGMVRGLFTPVEQGDIEGLVSVLDKEDVK
                     ESESIKMKFDTNKKYRELLDIPEGYSVPFGIAVGIPDGNLPNAREVVYKVSRV"
BASE COUNT         1892 a          447 c          912 g         1477 t
ORIGIN      
        1 tataatatat ttttgtaagg tatagtataa gtatattata ttttactata aaaatttgta
       61 ataaagtgaa aaaactagct tttcatgaaa taatatttta taatttaaga ttgtcttttt
      121 aataaagatt aacaaaaaaa atactataat tagtggtata atagttagag ttgaagattt
      181 taaataaagg taggtgtaat taagttggaa atatacttag acaatagcgc aactacaaaa
      241 ccttatcaag aagttataga taaaatggtt tatgcactta atacggaata tggaaatcct
      301 tcttctgtcc atagaaaagg tgtagaagtt gaaaaagcta taaaagaagt aagacaagat
      361 atagctaaat ctctaggagc gaaagaaaag gagatttatt ttacatcagg tggtacagag
      421 tgtaataata ctataataag aggtattact agtttaaata aaaaaagaaa aaatcacata
      481 atatctacta acatagaaca tccttctgtt ttaaatacat taaaagattt agaagaagat
      541 ggttttgaag taacttattt agaggtcgga aaagatggga aaataaatat agaggattta
      601 aaaaatgcga taaagtcaac tacatgctta gtaagcatga tgcatgttaa caatgaaata
      661 ggaactatac agccaatagg tgaagttgga aagtatttga agggtttaaa agaaaaaatt
      721 tatttccatg ttgatgctat tcagtcatat ggaaaaatta attttagacc atctaaatac
      781 aatatagatt ttatgagtgt aagtgcacat aaatttcatg gtccaaaggg aattggattt
      841 atgtatataa aagaaaataa tcgccttaag cctatgttaa caggtggtgg tcaggaaatt
      901 ggaattaggt cgggaacaga aaatgtacct ggaatatatg gtcttggaga agctgttaga
      961 atactaaaca aagatttaga tgttgttatt tcgaaagtaa ataacttaaa aaatatatta
     1021 aaaaatgaaa taattgataa tatagaagat ataaaaatca attctccaga agatggagta
     1081 tgtcatatat taaatgtatc atttagaggg acaaaaggag aagttttact tcattaccta
     1141 gagcaaaaag gtatttatgt atcaactggc tctgcatgtt cttctaaaaa gaaaggtagt
     1201 tacgtattaa atgctatagg tcttacaaat gaagaaataa atggaacaat aagatttagt
     1261 ttatctgata tgaatacaga agaagaaatg ttagaagctg tgaaagtttt gaaagaatca
     1321 atttgtgact taaggtcaat aatgaaaaga aaataaagaa tactgtatag atagtgataa
     1381 taaattagtt taagaggtga aatggtgtat aatatattaa tagtaaagta tggagaaatt
     1441 ggagtaaaag gaaagaatag atatatattt gagaataggc ttataagaaa tataagaaat
     1501 atgttaaaac caattggaag atttaatgta tataaagagt atggaagaat atatgttgat
     1561 ttagaagact atgattatga agaagtaatt gaagaagtta gaaaagtatt tgggatagtg
     1621 ggtgtgtgcc ctggagtaag agctaaaaaa gattatgata cattaaaaga aatagcttta
     1681 aaaatgttag aagaaaaaat agaggctgga tataaaactt ttaaggtaga gtcaagaaga
     1741 ggagataagt ctttcgggtt gacttctcaa gaaatgagta tggatatagg tggatactta
     1801 ttatcaaagg taggagatag gattaatgtt gatgtaagaa atccagaagt taaaataaag
     1861 tgcgaataca gagaatttca tactatggtc tatagtgata ctatacctgg atatggtgga
     1921 ttgccacttg gaacgaatgg tagagctatg tctcttttat caggaggtat agatagtcca
     1981 gtagctacat ggatggttgc aaaaagaggt atggaggtag aggcagttca cttccatagt
     2041 tatccattta caagtgaaag gtcacaggaa aaagttaagg atttagctaa aatactggca
     2101 aaatactgtg gtagagtaag acttcataaa gttaacatat tagaaataca aaaagcaatt
     2161 ggtgagaatt gtaatgaaga agaagctact attctttcaa gaagatttat gatgaggata
     2221 gcacagagac tttctgaaaa aagacattgt gatgctttaa ttacaggtga aagtattggg
     2281 caggttgcat ctcaaactat acaagggctt acttgtacta atgccgttgt agacttacca
     2341 gtgtttagac cacttatagc aatggataaa tcagatatag ttgatatagc caaaaaaata
     2401 gggacttttg aaacatctat agtgcctgaa gaagattgtt gtagtgtatt ttctcctaga
     2461 aagcctgtca ctaaacctag attagagaaa atagaaaaat ctgaaacagc acttgatatt
     2521 gaaaaattag tacaggatgc tattgacaaa atagaggtag aggatattga gttttagcat
     2581 acaagttatt taattactaa attgaatatt gagtatatta gtagttctgt aagtatatta
     2641 gtagttctgt tgaaaggatt tatgtagaca atttattaat atatagtatt taaaaataag
     2701 tactataatt ttatttaatg ggaatgatta ttatgaataa aaagggtttt acattaattg
     2761 aattgttggt agttatatct ataataggaa ttttagttat agtagctgtt ccagcgttat
     2821 ttagaaatat agaaaaaagt aaggcagtta catgtctttc taatagagaa aatataaaga
     2881 ctcaaattgt tattgcaatg gctgaggaat caagtaaaga caagaatgaa gtcataaaag
     2941 aggtattaga aaacaaagat ggtaagtact ttgaaacaga accaaagtgt aagtcaggtg
     3001 gaatatattc agcaacgttt gatgatggtt atgatggaat aactggaata gaaagcattg
     3061 caaaagtgta tgttacttgt acaaaacatc cagatggtat tgaaatggct agggatatac
     3121 atcaaagtat gaaagatttg attgcatcat ttgcacaaga cccttctata ataccaggag
     3181 cttcaaaggg caatgatgat tttagaaaat atttattaga caataaatat aaaaatgggt
     3241 ggcctacaat tccagatgaa tttaaggcaa aatatggatt aagtaaggat acactatata
     3301 tacaaccata tgcatataat cctactaaat ctgatgctac tgtagttgta tttgcaaata
     3361 ataagactgg aggtaattgg tatacttccc tagtttacga ttatgatgaa ggtagatggt
     3421 ataaaggtaa aaatggtatt tctgttgcag gtaggtcatg ggatgttgac acagatagtg
     3481 ttaagtctgt aaaaacagag attcattcta aagagggatg gggtccttta aattaatata
     3541 tcatgtttta ttaatctggt attgattaaa ctatagaaaa gagcagtttc tatagatgac
     3601 gaataccaga ttttcattta tatgtataat taagatatat taaaagtatt tatattttta
     3661 agtcttcaca tacaagctaa agataattat aataatattg taaagaaatt taattataag
     3721 attaattttc tgaagattta gtatttgtac taagaaatac ataaaaaggg gaatagatat
     3781 gaataataat tttcaagaca accaaacaat aaatttaata caaagtcgta gaagtatacg
     3841 aaaatttaca acagagcaaa ttagtgatga gcaagtaaac acattattac actgtgcatt
     3901 tgcagcacct tcaggatgta ataaacagcc ttggcacata actgttgtgc aagaccagaa
     3961 acttttaaaa gagattagtg atgatacttt atctaggatt catgaagtga gtaatgttga
     4021 gataaataaa aactttaagt tattttatgg tgctccaacc gttttattta tttcttatga
     4081 tgaaagtagt tcatgggctc catatgatat aggaatactt acagggaata taacaacagc
     4141 tgcacaagca ctagggcttg gaagttgtat aataggaatg gttagaggtt tatttacacc
     4201 tgttgaacaa ggggatattg aaggtcttgt gagtgtattg gataaagaag atgtaaagga
     4261 atcagagtca ataaagatga agtttgatac aaataaaaaa tacagagaac tacttgatat
     4321 accagaaggg tattctgtac catttggtat tgctgtaggt attccagatg gaaatttacc
     4381 aaatgctaga gaggtagttt acaaagtttc cagagtttag gataaagtat tgcaagaacc
     4441 aatcagttac ttgaagaatt aaaccagtaa tatacaaata aattgatgga agaggaagct
     4501 atttaaaaag tagtttagat ttttcattgt aaaataatta aataaagaat aaggtgataa
     4561 gtattttatt tattatctta ttctttttta tttttgtttt gtagaatgat aaaaataagg
     4621 attaagtgta ataaaataga aaacaagtat gttaatttta agtatatgct ttaaaattta
     4681 tccaagttaa aaatttaaga tatcttttca gtataatgga aaaaatgt
//
LOCUS       DAMJYN010000167         4661 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.173, whole genome shotgun sequence.
ACCESSION   DAMJYN010000167 DAMJYN010000000
VERSION     DAMJYN010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4661)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4661)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4661
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.173"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            233..1045
                     /locus_tag="PC466_003596"
     CDS             233..1045
                     /locus_tag="PC466_003596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mrp/NBP35 family ATP-binding protein"
                     /protein_id="HDF2770946.1"
                     /translation="MADCNSCPSKGNCNSQSNCSIENNPNNKFGKIIGVMSGKGGVGK
                     STVTALLANKLNKMGYKVGILDSDITGPSIPRLMGVKNVKAYSDGSYIYPVENSNNIK
                     VMSINLMIDDENEPVVWRGPLLGGVVKQFYTDVLWEELDYLLIDMPPGTGDVALTVMQ
                     SIPISGIVMVSVPQDLVSMIVSKAVNMAKKMNINVLGVIENMSYIQCPDCSKKIKLFE
                     GESTEKFLDDLDLELLGELPMTKEIIDITHNGVTEISDDLDSILTNVVEKIK"
     gene            complement(1134..1325)
                     /locus_tag="PC466_003597"
     CDS             complement(1134..1325)
                     /locus_tag="PC466_003597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770947.1"
                     /translation="MERLMELIERKFLKDVELLELEDIENVIECKMTQPYNAHYNEYL
                     VKVKNGDEVEEYFVYLKHR"
     gene            1630..1836
                     /locus_tag="PC466_003598"
     CDS             1630..1836
                     /locus_tag="PC466_003598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2770948.1"
                     /translation="MFKKKSGYTFTNFLNKVRVEKNKKYLLKKDLSILDVTVLIGFNS
                     QNYYSIIFKKFNNLTPIEYKNIYN"
     gene            2145..3764
                     /locus_tag="PC466_003599"
     CDS             2145..3764
                     /locus_tag="PC466_003599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HDF2770949.1"
                     /translation="MNIVISLIGGLGLFLYGMSLMGEGLQKSAGDKLKKIIELLTSNV
                     VMGVLVGTVVTGIIQSSSATTVMVVGFVNAGIMNLSQAIGVIMGANIGTTVTAQLVSF
                     NLEGIAPIALGIGILFYLFTSNQKTKHLSEILIGFGILFTGMEFMKDAVAPLAEYKAF
                     TDALLYFSKNPVLGILAGFAITGIVQSSSASMGMLIALASQGILPLSSALPILYGDNI
                     GTCVTSLLSSVGASRNARRAAVMHLSFNVIGTIIFMLVLNKPISAIVTHFDPTDTARQ
                     IANAHTLFNLTNVIILLPFSKYIVKLANRLIPIKETESEIVNNTKYLDERMFSTPSIA
                     LGNTVQEVVRMGHKATNSLEHSIAGFLNKSNEDINKAFESEKVVNKLQKDILNYLLKL
                     SKEPLRDDERFRTDLLFNTVNDIERVSDHAENIAELAMSVKEMNISFSDSAIREIYEI
                     YNKTITNFKDALIVLDVKDFELANKVLEVENEVNYLEKTFRNSHMIRLNNGNCTIDAG
                     VLYLDLLTNLERISDHSTNIVKQVLKLKQKI"
     gene            4138..4332
                     /locus_tag="PC466_003600"
     CDS             4138..4332
                     /locus_tag="PC466_003600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HDF2770950.1"
                     /translation="MINYMVEIIYSEKISEVENMLKIENIQYEFTSRDGFIFFGFYEM
                     TDAYRFETLCSDEKIRFKRI"
BASE COUNT         1748 a          539 c          631 g         1743 t
ORIGIN      
        1 aaatattttc tatatattta tatgactaag ttctataact aaattgaaat aatcactttt
       61 tcaagaatgt tataattttt ttattgtatt ctttttgcta tagtctatga ataaatcaat
      121 agaaaatctt ctaagttgct tttaaataat gactttatgg ttcaattgta ctaaaatagt
      181 atatgtaggt tacaaataat ctaataaata ttaaagtttg gaggtaatag atatggcaga
      241 ttgtaattca tgtccatcaa agggaaattg taatagtcaa tcaaattgtt ctattgaaaa
      301 taaccctaac aataaatttg gaaaaataat tggtgttatg agtgggaagg gtggagttgg
      361 aaaatcaact gtaactgctt tacttgctaa taagctaaac aaaatgggat ataaggttgg
      421 tatattagat tcagatataa ctggaccaag tattcctaga cttatgggtg taaaaaatgt
      481 aaaagcttat tctgatggct cttatattta ccctgtagaa aactcaaata acataaaagt
      541 aatgtctata aaccttatga tagatgatga gaatgaacct gttgtttgga gaggaccttt
      601 acttggagga gttgtaaagc aattttatac tgatgtactt tgggaagaat tagactattt
      661 attaatagat atgcctcctg gtactggaga tgttgcctta acggttatgc aatctattcc
      721 tataagtgga atagttatgg tttcagtacc tcaagatttg gtatctatga ttgtatcaaa
      781 agctgttaat atggctaaaa aaatgaacat aaatgtcctt ggagttattg aaaatatgag
      841 ttatatccaa tgtcctgatt gttctaaaaa aatcaagtta tttgaaggag aatctactga
      901 aaagttttta gatgatttag acttagagct tttaggagaa cttcctatga ctaaagaaat
      961 tatagatatt actcataatg gagttacaga aattagtgat gatttagatt caatattgac
     1021 taatgttgtt gaaaaaatta aataaataaa aattttataa ttttatattt atcaaaaaaa
     1081 gaggcttgta tttattttat aatcatacaa ataaatataa acctctttta tgtttatcta
     1141 tgttttaaat acacaaaata ttcttctact tcatctccat tttttacttt tactaagtat
     1201 tcattataat gagcattata tggctgtgtc attttgcatt ctattacatt ttctatgtct
     1261 tctaattcta aaagttctac atcctttaaa aattttcttt ctatgagttc cattaatctt
     1321 tccataatat atcctcactt cccctataat taagataaac tatatatcct cttaatacag
     1381 agtttatctg tttattatat tatatccaat atattacagt ttctaacatc attcataaat
     1441 tattttaaca aatagagatt gattttttaa taaatatgcc ttgataaaat gaaacataga
     1501 ccaactctta gttttatgta aagaaaactt aaagaaaact atagattata ttcacaaaaa
     1561 ctactcagaa gatataacag taagtaatat atgtaatgaa ttacaactta ataaaagtta
     1621 tttttttctt tgtttaagaa aaaaagtgga tatactttta ctaatttttt aaataaagtt
     1681 agagttgaaa aaaacaaaaa gtatctatta aaaaaagact tgtctatttt agacgttact
     1741 gtactaattg gattcaatag tcaaaattac tatagtataa tttttaaaaa gtttaataac
     1801 cttacaccaa ttgaatataa aaatatttat aactaaaaaa tatcattcta aaaggatgct
     1861 atttttttac atatttttta caattatagt taattctttg ttaaattgat tgtacataaa
     1921 atactaaaaa tctaagttca agtatttaaa ttgctatata tcataaattt tctaaaatta
     1981 acaacaactt aaaaatttaa cattctctta acgtatactt aacaaaacat taatatttct
     2041 attgacaaaa tttgttattc tatattatgg aaacaataaa ttttagttaa taaagtttat
     2101 aattcagata aaaaaactat taatttctta agggaggaaa tatcgtgaat atagtaatta
     2161 gccttatcgg tggacttgga ctttttcttt acggaatgag tttaatggga gaaggtttac
     2221 aaaaatcagc aggagacaaa ttaaaaaaaa ttattgaact cttaacaagt aatgttgtta
     2281 tgggtgtact ggtaggtaca gtcgttacag gtattataca aagttcaagt gctactactg
     2341 ttatggttgt aggatttgta aatgcaggta taatgaatct aagtcaagct attggtgtaa
     2401 taatgggggc aaatataggt actacagtta ctgctcaatt agtttcattt aatcttgaag
     2461 gaattgcacc aattgcttta ggtataggta ttttattcta tttatttaca tcaaatcaaa
     2521 aaacaaagca tttatctgag atacttatag gttttggtat attatttaca ggaatggagt
     2581 ttatgaaaga tgcagtagct ccacttgctg aatataaagc attcactgat gcacttttat
     2641 attttagtaa aaatcctgta ttaggtatat tggcaggatt tgccataact ggtattgttc
     2701 aaagttcaag tgcatctatg ggtatgttaa tagcactagc ttctcaagga atacttcctc
     2761 tatcatctgc tttacctatt ctttatggag ataatatagg tacttgtgtt acttcacttt
     2821 tatcaagtgt tggtgcaagt agaaatgctc gacgtgcagc tgtaatgcat ttaagtttta
     2881 atgtcattgg tacaataata tttatgcttg ttttaaataa acctatatca gccatagtta
     2941 ctcattttga cccaactgat acagctagac aaatagcaaa tgcacatact ttatttaatc
     3001 ttacaaatgt tataatatta ttaccatttt ctaaatacat agttaaatta gcaaatagac
     3061 ttatacctat taaagaaact gaatcagaaa tagtaaataa tactaagtac ttagatgaaa
     3121 ggatgtttag cactccatct atagcacttg gtaatactgt acaagaagtt gtaagaatgg
     3181 gtcataaagc tacaaactct ttggaacatt caattgcagg atttttaaat aagagcaatg
     3241 aagatattaa taaagctttt gagtcagaaa aagttgtcaa taagttacag aaagatatat
     3301 tgaactattt gttaaaactt tctaaagaac ctcttagaga cgatgaacgc tttagaacag
     3361 atttgctttt taatactgta aatgacattg aaagagtctc tgaccatgca gaaaatatag
     3421 ctgaattggc catgagtgtt aaggaaatga acattagttt ttctgatagt gcgataagag
     3481 aaatatacga aatatacaat aagacaatta ctaattttaa ggatgcctta atagttttag
     3541 atgttaaaga ttttgagtta gcaaataaag ttttagaagt tgaaaatgaa gtaaattatt
     3601 tagaaaaaac ttttagaaat tcacatatga ttagactaaa taatggaaat tgtacaattg
     3661 atgctggtgt actttatctt gacttactta ctaatctaga aagaatttct gaccactcaa
     3721 caaatatagt aaaacaagta ttaaaactta aacaaaaaat atagtgatta tttttatata
     3781 taatcttaat caatgagaag taagaagcta tagataatgc ttatatcatt tatggcttct
     3841 tattttttat gtaatactca aatttttata gtattctctt attattaaac agcttctgcc
     3901 tagaatattc catatatata tgacttcttt cataaaactt gaactgccca taactaaagt
     3961 cacaagtata cataactatt ttttaatcaa ttataaccaa tatttatttt atttatcttc
     4021 attttaattc ttcattcaat aatgtaataa gattattttt tatttggata ctattatatc
     4081 atctaaatat gttattatat atttggatat tttcatatta ataggaggga ttctacaatg
     4141 ataaattata tggtagaaat tatatatagc gaaaaaataa gcgaagtaga aaacatgttg
     4201 aaaattgaaa atatacaata tgaatttact tctcgtgatg gctttatatt ttttggtttt
     4261 tatgagatga cagatgcata tagatttgag actttatgtt cagatgaaaa aattcgattt
     4321 aaaagaatat aataaataaa aaaagtacat atttctaaac tatttgtttt tcaaatttag
     4381 gttgtgtttt aatgtagtgt tgatatcata aacaatttta ataataaaaa agtaggaata
     4441 ttatattaat atgctcctac tttttactca tatttattaa tattatttat caaaactacc
     4501 ctacaaactg gaatttatca ttctttcata attttaaact atcatattta aaatatataa
     4561 aattctactt gatttttgta taaacgtaat atcaatcatt atccaattta aaagtatttt
     4621 ttagtaattt ccatttcatt ttcttttaac atattaatta a
//
LOCUS       DAMJYN010000168         4565 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.174, whole genome shotgun sequence.
ACCESSION   DAMJYN010000168 DAMJYN010000000
VERSION     DAMJYN010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4565)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4565)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4565
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.174"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            202..1008
                     /locus_tag="PC466_003601"
     CDS             202..1008
                     /locus_tag="PC466_003601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HDF2770951.1"
                     /translation="MGMILSTLGINLYLAPAKLLSGGVAGICVILYKLFGINQGISSF
                     LMNIPIFIIARKYFDNKFLLISFVNMLLFSLALGLTQDIAKYFPIDDTMLQCIYGGAL
                     TGIGMGLTFKARATAGGLDIIAAIMKRKYDIPMKNTFLFINFFVVCAGAFLFGAKLVM
                     YTLITMYIISFTMDIGKDCFDRKKSILLISNKYDEISKVIMNKMGRGVTFLEAEGAYT
                     QNKKKMIYCIISANEIGKFKDLIYDMDSEAFISVNNVEEVKGGGFKDKFL"
     gene            1135..1407
                     /locus_tag="PC466_003602"
     CDS             1135..1407
                     /locus_tag="PC466_003602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770952.1"
                     /translation="MLRERFVVRNHHNPHTSGCCGTGGEGCCGGDNHEHSHQHSHSHG
                     HEHEHVNGVGHDHNHDDGFSGTHEHSHEHTHTHGHEHSDGHTHEHK"
     gene            complement(1570..2142)
                     /locus_tag="PC466_003603"
     CDS             complement(1570..2142)
                     /locus_tag="PC466_003603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2770953.1"
                     /translation="MKTNNMKQAILSSATNLIAKNGVQNTSLADIAKDVNISKGTLYY
                     HYASKDDIIYDIADTHLEVITSAILNCVKNVKSKNSQIEMVNLILEKISTIESRGRVH
                     MYLICEAITSNNDLKERIRLKYIEWRTTLKSEIVESLEKYNSSENEQDAESFSFLLMS
                     IVDGLVVQSLLKTEKIPYENIASFLVNHWI"
     gene            2326..3168
                     /locus_tag="PC466_003604"
     CDS             2326..3168
                     /locus_tag="PC466_003604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HDF2770954.1"
                     /translation="MDKIKLIVDSACDLPDDIIEKYNIEVVGLNVSFGEESYISGKEI
                     DNETFYRKMSESKVLPKTSCPSPDKFLEAYHCQEESVLVINISSGLSGTYNSALLAKD
                     MFEKEGNNKKVEVIDSLSGSIGIGQLVLKAAILIKEGKEIEEIVSIINKYKDNPPFFG
                     TLETLENAIKGGRINPIAGKIINTLNFKAIIQVADGVVTPIDKARGEGNSLKKLITLV
                     ESKIKDKEEKVLFIGHANCPEKAQKVREVMEKDVKYKDVVICEIGSVMGTYTSKGAIL
                     ITAI"
     gene            complement(3271..4347)
                     /locus_tag="PC466_003605"
     CDS             complement(3271..4347)
                     /locus_tag="PC466_003605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HDF2770955.1"
                     /translation="MKAQRLNAVLEQMKKDDISQMLVSDPTSIFYLTGVLIHPGERLL
                     ALYLNLNGNNKLFINELFPVSEDLGVEMVWFNDTQNPVEIITEHIDKNATMGVDKNWP
                     ARFLLNLIELGGGSKFVNSSYIIDTLRMCKDEEEKELMRIASKLNDKAMEQLKATVSG
                     ELTEKQLVGKLSKIYEDLGTDGFSFDPIIGFGPNGANPHGEPGNALVKPGDAIILDIG
                     CIKDNYCADMTRTVFYKEIPEKGREIFEIVLEANKRAEAIVKPGVRFCDIDAAARDYI
                     TEKGYGQYFTHRTGHSIGLEVHDKGDVSSINTDTVQPGMIFSIEPGIYLPGEFGVRIE
                     DLVLVTEDGCEILNKHDKEICVVG"
BASE COUNT         1665 a          587 c          712 g         1601 t
ORIGIN      
        1 ataaatatat taaaagaagg attaagacta ataacaattc aaaataaata acttatgtaa
       61 gaaccgtagg aactacgggg atagcttgtg gagaattagt aagacatatt ttagtatgca
      121 aaattctatg aagcaggaac cctgtgactt tagtcatggg aggttcagaa taacatattt
      181 ttacaatatg gtctgattat attgggtatg attctatcaa ccttaggaat aaatttatat
      241 ctagcaccag ccaagttatt aagtggagga gtagctggaa tttgtgttat attatacaaa
      301 ttatttggta taaatcaggg aatatcaagt ttcttgatga acataccaat atttattata
      361 gctagaaagt attttgataa taaatttttg ctaataagtt ttgtcaatat gttactgttt
      421 tctctagcac tggggctaac acaagatatt gctaaatatt tcccaataga tgatactatg
      481 ctacagtgta tttatggtgg tgcattaact ggtataggta tggggttaac ttttaaagca
      541 agagctactg ctggaggact tgatataata gcagccataa tgaaaagaaa gtatgatata
      601 cctatgaaaa atacattttt atttattaat ttttttgtag tatgtgcagg agctttctta
      661 tttggagcta aattggtgat gtacacttta attacaatgt atataatttc ttttactatg
      721 gatataggaa aagattgctt tgatagaaaa aaatctatac ttttaatatc aaataaatat
      781 gatgaaatat ccaaagtgat aatgaataaa atgggtagag gagtcacttt tttggaggca
      841 gaaggtgcat atacacaaaa taagaaaaag atgatttatt gcataatatc tgcaaatgaa
      901 ataggtaaat ttaaagattt aatttatgat atggatagtg aagcttttat ttctgtcaat
      961 aacgttgaag aagtaaaagg tggaggtttt aaggataaat ttctttaaga ttatatatgt
     1021 taattatata tgttaaaaaa tgccatatgt attgagatta tacctagtta gatgtatact
     1081 gtagttaatg gggtacatga agtattcaat aatatactag gaggtataag aattatgtta
     1141 agagagagat ttgtagtaag aaatcatcat aatccacata caagtgggtg ttgtgggact
     1201 ggaggagaag gatgctgtgg aggagataac catgaacatt cacatcaaca ttctcacagt
     1261 catgggcatg aacatgagca tgtaaatggt gtaggtcacg accataatca tgatgatggt
     1321 ttttcaggta ctcatgagca tagccatgag catacacata cacatggtca tgaacattca
     1381 gatgggcata cacatgaaca taaataaaaa cattttaaat ttataagaga tttttatttt
     1441 gtgattccat gaaggtttaa ataaaaattg aatgttttaa gtaaaaatta ttgagaataa
     1501 ataagaaagt gaactgttaa agtagataac ttaaatagtt cacttttatt aattatctaa
     1561 gtattaagtt taaatccaat gattaactaa aaaagaagct atattttcat aaggtatttt
     1621 ttctgttttt aataaacttt ggacaactaa accatcaact attgacatga gtaaaaaaga
     1681 aaatgattca gcatcctgtt cattttcgct actattatat ttttctagtg attcaacaat
     1741 ttcagattta agagtagttc tccattcaat atattttaat cttattcttt cctttaaatc
     1801 attatttgaa gtaattgcct cacaaataag atacatatgt accctaccac gactttctat
     1861 agtagatatt ttctctaaga ttaagttaac catttctatt tgagaatttt ttgatttgac
     1921 attttttaca cagtttagta tagcactagt tataacttct aaatgagtat ccgcaatatc
     1981 atatataata tcatctttag atgcgtagtg ataatacaaa gtacctttac ttatatttac
     2041 atcttttgca atatcagcaa ggctagtatt ttgaactcca tttttggcta ttaaattggt
     2101 tgcagatgat aaaatagcct gtttcatatt atttgttttc ataaaaccta cctttccatg
     2161 tatatttata acaaattaat aacattataa gcttatgaat atttattgtc aataaagcga
     2221 gaatctatat ctattgactt tttttcattc aatatataaa ataataatta aatcggtcgt
     2281 acgaccgact gaataaataa aataatatct tatagtgagg ttaatatgga taaaataaaa
     2341 ttgatagtgg acagtgcatg tgacttacct gatgatataa tagaaaaata caacatagaa
     2401 gttgttggtt taaatgtatc ttttggagaa gaaagttata tatctggaaa ggaaatagat
     2461 aatgaaactt tctatagaaa aatgagtgag agtaaagtac taccaaaaac atcatgtcct
     2521 tctcctgata aatttttaga agcataccat tgtcaggaag aaagtgtatt ggtgattaat
     2581 ataagttcag gattatctgg gacttataat agtgcacttt tagcaaaaga tatgtttgaa
     2641 aaggaaggaa ataacaaaaa agttgaggtt atagattcac ttagtgggtc aattggaata
     2701 ggacaattag tgttaaaagc agcaatatta ataaaagaag gaaaagaaat tgaagagatt
     2761 gtttcaataa taaataaata taaagataat cctccatttt ttggaacact tgaaacttta
     2821 gaaaatgcta ttaagggtgg tagaataaat ccaatagcag gaaaaattat aaataccttg
     2881 aattttaagg cgataataca agttgcagat ggcgttgtaa ctcctataga taaggcaaga
     2941 ggtgaaggaa acagtttgaa aaagctgatt actttagtag agtcaaaaat taaagataaa
     3001 gaagaaaagg ttttatttat aggacatgct aattgcccag aaaaggctca aaaggtaagg
     3061 gaagttatgg aaaaggatgt aaaatacaaa gatgttgtaa tctgtgaaat tggttcagtg
     3121 atggggacat atacttcaaa gggtgcaatc ttaataactg caatataaat aatggattga
     3181 aataaatcat agattgagaa attaaagcca tataaaaatg tttaaaacat ttttatatgg
     3241 ctttttaatt ttatcaaatt gattttagaa ttaaccaact acacatattt ctttgtcatg
     3301 tttgtttaat atctcacaac catcttcagt aacaagtact aaatcttcta ttctaactcc
     3361 gaactcacct ggtaaatata tacctggctc tatagagaat atcattcctg gttgtacagt
     3421 atctgtattt atagaagata catctccttt atcatgaact tcaagtccta tagagtgacc
     3481 agttctatga gtgaagtact gtccatatcc cttttcagtt atgtagtcac gagcagcagc
     3541 atctatatca cagaatctaa cacctggttt tacaatagct tcagctctct tattagcttc
     3601 aagaactatt tcaaatattt ctctaccttt ttcaggtatt tctttataga atacagttct
     3661 tgtcatatca gcacaatagt tatcttttat acaacctata tctaatatta ttgcatctcc
     3721 tggtttcaca agtgcatttc caggttcacc atgtggatta gctccattag gtccaaaacc
     3781 tataataggg tcaaatgaaa atccatcagt acctaggtct tcatatattt tagataattt
     3841 accaacaagt tgtttctctg taagttcacc agaaacagta gctttaagtt gttccatagc
     3901 cttgtcattt aattttgaag ctattctcat taactctttt tcttcttcat ctttacacat
     3961 tcttaaagta tctattatat aagatgaatt tacaaactta cttcctccac ctaattctat
     4021 taagtttaat aagaatctag ctggccagtt tttatcaaca cccatagtag catttttgtc
     4081 tatatgttca gttattattt ctactggatt ttgagtatca ttaaaccaaa ccatttcaac
     4141 acctaaatct tctgaaactg ggaataattc atttataaat aatttattat tgccatttaa
     4201 atttaagtat aatgctaata atctttcacc tggatggatt agtactcctg taagataaaa
     4261 tatagaagta gggtcactta ctaacatttg agaaatatca tcttttttca tttgttcaag
     4321 tacagcattt aatctttgag ctttcataat aatttcctcc taatcaaaat tcaatacaaa
     4381 tcaattttag cattattaaa caaaaaagag tatacttttc ttctagaaat ataaaaaaag
     4441 tttgttatat attttttata ttaagtttaa tctctacttt tgcattaaat acggaagtaa
     4501 aatgactttt tattgtgaaa attctataaa agtaataaat taagtctata aagttatgta
     4561 tttta
//
LOCUS       DAMJYN010000169         4542 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.175, whole genome shotgun sequence.
ACCESSION   DAMJYN010000169 DAMJYN010000000
VERSION     DAMJYN010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4542)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4542)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4542
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.175"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            163..810
                     /locus_tag="PC466_003606"
     CDS             163..810
                     /locus_tag="PC466_003606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2770956.1"
                     /translation="MNILIADDEISMLKILCAYFKKENFNVFTAKNGEEALDIFYENK
                     IDLAILDWMMPIIDGIEVCKEIKENSNTRVLMLTAKSQSEDEIEALNIGADEYIKKPF
                     DPRVLIIRAKKLINYKNTINIKDLKIDFGSSKVFKGDKELLLTKKELELIRCLINNKG
                     MVLSREKLLDLVWGLDYEGDFRTVDTHIRRLRVKIGEDIIKTYRGLGYSLEDFND"
     gene            803..2197
                     /locus_tag="PC466_003607"
     CDS             803..2197
                     /locus_tag="PC466_003607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2770957.1"
                     /translation="MTKLNKKLSISISIVVVVVYIISIIINSMFIHRYYLHEKRNILD
                     NVENEIKDKDIDKLKSDITLIEEKNNIDIVYIELDKNHKDKGNIDKINQDLLNAFWKK
                     GLSLNKFWIEENSLNNIDKKSINKIYNQGKTKYSLLVKFIKKDNYLFAISIPIEHSEE
                     TIGIVNRFNIIMGIFSVVIITILTFILSNRVIKPMERLKFLSKDISELNFRTEDIKTN
                     DEIEELAYSINIMSEKLEKAHNELNKRNENLKTFISDASHEMKTPIALIKAYAIGMKD
                     GLDDGTYTDTIIEQAENMTNTINSLLYWAKYEKKERSLCLVDLKERLYKSLKNYELLI
                     ERGSISVKCSVDDKELIISSDEDSIDMVFNNLISNAIKYTNNNEIEINLFEENERIIL
                     SIKNGIDYNMGDDIENMWKPFYVLEKSRSKELSGTGLGLTIVRTILEENNFRYRVEIC
                     DGIIEFYIIFIKVI"
     gene            2622..>4542
                     /locus_tag="PC466_003608"
     CDS             2622..>4542
                     /locus_tag="PC466_003608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HDF2770958.1"
                     /translation="MKIPKKIAAMLTVTMIAGSSTAGIASAQTVATNLTGQERYETAV
                     KISQDGWKNADEVVIVNDSSIADALSATPFAKAKNAPILLTSKDKLNDKTKAEIQRLK
                     AKKVYLIGGTSVLSTNIEKEIKDLKISFERISGAERYQTSLELAKKLDAISDVKKIAV
                     VNGEKGLADAVSVGAPAAQNNMPVILADSKNGTAVADKFIKDAGITQSYVVGGESSIS
                     EAVKNKLPNSTRLGGTDRNDTNAKVIKEFYKKTDLKNAYVTKDGMNKQDQLIDALAVG
                     VLGAKNQSPVVLVGKNLSASQKSLVNSKSFDKITKVGGNGNETAFNEMKSLQEVKTVE
                     AKTISELKSAIDKATANDVINFKPTSEVKEAFTIQTDKAITVNLNGTYTKTVTINMPN
                     GDVNNYAKVDDVVIDDVKDGTFVNYGKITNLKVNDKNGAKIENNSKGEIGSLTVASGA
                     SQVKVTNGGKITTVTNNSKGTTIDNKGTISSVKGDNSPTISGNSPSSNSSGGSSSSGG
                     SSHGGGSSSSKVDKVVLKNTITAANKLYNEAIEGTNVGEYKVGSKAIYKTAIDKAQAI
                     LDKSGVTQKEVNDAVTALNTATDTFKAGKVVAVDKTALQDAVTAATALHAKATEGTAE
                     GNYAVGSKATYKTAID"
BASE COUNT         1981 a          442 c          796 g         1323 t
ORIGIN      
        1 ttaaaatata taatcgagat attgttaaga cattgtcgag atattataat atataactaa
       61 tgtattataa atagttgtaa acttcctgta acatatattt tatataatta aagtaatgga
      121 tataatatga aatataataa tgaattttag ggatgtgaat aaatgaacat attaattgct
      181 gatgatgaaa ttagtatgct taagatactt tgtgcatatt ttaaaaaaga aaacttcaat
      241 gtgtttactg caaaaaatgg ggaagaggct ttagatattt tttatgaaaa taagatagac
      301 ttagctatat tagactggat gatgccaata attgatggaa tagaggtttg taaagagata
      361 aaggaaaata gtaatacaag ggtacttatg ttgactgcca aaagtcaaag tgaagatgaa
      421 atagaagcac tcaacattgg agcagatgaa tatataaaaa aaccatttga tcctagagtt
      481 ttaataataa gagctaagaa actaataaat tataaaaata caattaatat taaagattta
      541 aaaatagatt ttgggtcaag taaagttttt aaaggtgata aggaattatt attgactaag
      601 aaagaattag aattaattcg ttgtttaatc aataataaag gaatggtttt atctagggaa
      661 aaacttttag atttagtatg gggattggat tatgagggag attttagaac agtagatact
      721 catataagaa gattaagggt aaaaatagga gaagatataa taaaaactta tagaggatta
      781 gggtatagtc tggaggattt taatgactaa actaaacaaa aaattgtcca taagtatatc
      841 tatagtagtt gtagttgttt atataatatc tataattata aatagtatgt ttattcatag
      901 atattattta catgaaaaaa gaaatatatt ggataatgtt gaaaatgaaa ttaaagataa
      961 agacatagat aaattaaaat cagacattac tttaattgaa gaaaaaaata atatagatat
     1021 cgtatatata gaattagata aaaatcataa agataaaggt aatatagata aaataaatca
     1081 agatttatta aatgcatttt ggaaaaaagg tttaagttta aataagtttt ggattgaaga
     1141 aaatagttta aataatattg ataagaaaag tataaataag atatacaatc aaggtaaaac
     1201 aaaatatagt ttgcttgtaa aatttatcaa gaaggataat tatttgtttg ctatatctat
     1261 acctatagaa cattctgaag aaactattgg cattgtaaat agatttaata taataatggg
     1321 aattttttca gtagttataa taactatact tacatttata ttatcaaaca gagttataaa
     1381 acctatggaa aggttaaagt ttttatctaa agatatatct gaattaaatt ttaggactga
     1441 agatataaaa acgaacgatg aaatagaaga gctagcttac agcataaaca taatgagcga
     1501 aaaacttgaa aaagcacata atgaattgaa taaaagaaat gagaatctaa aaacttttat
     1561 atcagatgca tctcatgaaa tgaaaactcc aatagcactt ataaaagcat atgcaatagg
     1621 tatgaaagat ggtttggatg atgggactta tacagataca ataattgaac aagcagaaaa
     1681 tatgaccaat acaataaatt ctcttttata ttgggcaaaa tatgagaaga aggagagaag
     1741 tctgtgtctg gtagatttaa aggaaaggtt atataaaagt ttaaaaaact atgagctgtt
     1801 gatagaaaga ggtagtataa gtgttaaatg cagtgtagat gataaagaac ttataataag
     1861 ttcggatgaa gatagtatag atatggtatt taataatttg attagtaatg ctataaagta
     1921 tactaataat aatgaaatag agattaatct ttttgaagag aatgagagaa ttatattatc
     1981 cataaaaaat ggtatagatt acaatatggg agatgatata gaaaatatgt ggaagccttt
     2041 ttatgtttta gagaagtcga gaagtaagga gctttctggt actggtcttg gtcttaccat
     2101 agttagaact atacttgaag aaaataattt tagatacagg gttgaaattt gcgatggaat
     2161 tatagaattt tatattatct ttataaaagt aatttgaatt aaaatgtaaa tataaagaat
     2221 aattaaaaaa atatcgcaat tatttgtttt tcatatggat aaaattggtt atttaatata
     2281 taattacaag tataaataat aaaatttatt tgtaaaaaga gtagcacttt taattctaaa
     2341 ggctactttt tttatacaaa accatgtttt ttataacaat tcattaacat aaaaatcaaa
     2401 cttaccttaa aatataaatt tacaaatttt tcaatcaata agaaaatttc tctattcctt
     2461 acataatgac tgtaatgtaa caaaataatt acaaattaat tatgaaatca ttatagttag
     2521 aaacctcttt aaaattagat attaagtatc ctttagaatt agaacgggaa caaagttaaa
     2581 aaattaagta atatcaaatg gacaaggggg aagaaaataa aatgaaaata ccaaagaaga
     2641 ttgctgcaat gcttacagtt acaatgatag ctggaagttc aacagcaggc atagctagtg
     2701 cacaaactgt ggcaacaaat ttaacagggc aagaaagata tgaaactgct gttaaaataa
     2761 gtcaagatgg atggaaaaat gctgatgagg tagtaatcgt aaacgactca tctatagcag
     2821 atgctctatc tgcaacacca tttgcaaaag caaaaaatgc tccaatactt ttaacaagta
     2881 aagataaatt aaatgataag acgaaagcag aaatacaaag attaaaagct aaaaaagtat
     2941 acttaatagg tggaacttct gtattaagta caaatataga aaaagaaata aaagatttaa
     3001 aaatatcttt tgagagaatc tctggagctg agagatatca aacatcctta gaattagcaa
     3061 agaaattaga tgctataagt gatgttaaga aaatagctgt agttaatggt gaaaaaggac
     3121 ttgcagatgc tgtaagtgta ggagcaccag ctgcacaaaa caatatgcca gtaatacttg
     3181 ctgattctaa aaatggaaca gcagttgcag acaaatttat aaaagatgct ggaataactc
     3241 aatcttatgt agtaggtgga gagagttcaa tttctgaagc tgttaaaaat aaactaccaa
     3301 atagtacaag actaggtgga acagatagaa atgatacaaa tgcaaaagta ataaaagaat
     3361 tttataaaaa gacagattta aaaaatgctt atgtaactaa agatggtatg aataaacaag
     3421 accaacttat agatgcacta gcagtaggtg tattaggtgc taaaaatcaa tcaccagtag
     3481 ttttagttgg aaagaactta tcagcttcac aaaaatctct agttaactct aagagttttg
     3541 ataagataac taaagttggt gggaatggta atgagacagc atttaatgaa atgaagtcat
     3601 tacaagaagt aaaaacagtt gaagctaaaa caatttctga attaaaatca gctatagata
     3661 aagctactgc taatgatgtt ataaacttta agccaactag tgaggttaaa gaagcattta
     3721 caatacaaac tgataaggcg ataacagtaa acttaaatgg tacatataca aagactgtga
     3781 ctatcaacat gcctaatggt gatgtaaata actatgcaaa agtggatgat gtagttatag
     3841 atgatgtaaa agatggaact tttgttaact acggaaaaat aactaactta aaggttaatg
     3901 ataaaaatgg agccaagata gaaaataatt ctaaaggtga gattggtagt ttaacagtag
     3961 catctggagc aagtcaagta aaagtgacta atggtggtaa gataactaca gttacaaata
     4021 attctaaagg aactactata gataataaag gtacaataag tagtgttaag ggagataatt
     4081 ctccaacaat aagtggaaat agtccaagtt ctaactcttc aggaggaagt tcatcaagtg
     4141 gaggttcttc acatggagga ggaagttctt catcaaaagt agataaagta gttttgaaaa
     4201 atacaataac agcagcaaat aaattgtata atgaagcaat agagggaaca aatgtaggtg
     4261 aatataaagt agggtcaaaa gcaatatata aaacagcaat agacaaagca caggcaatat
     4321 tagacaaatc tggtgtaaca caaaaagaag taaatgatgc agtaacagca ttaaacacag
     4381 caacagacac atttaaagca ggaaaagtag tagcagtaga taaaacagca ttacaagatg
     4441 cagtaacagc agcaacagca ttacatgcta aagcaacaga aggaacagca gaaggaaact
     4501 atgctgtagg atcaaaagca acgtataaaa cagcaataga tg
//
LOCUS       DAMJYN010000170         4523 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.176, whole genome shotgun sequence.
ACCESSION   DAMJYN010000170 DAMJYN010000000
VERSION     DAMJYN010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4523)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4523)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4523
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.176"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(119..664)
                     /locus_tag="PC466_003609"
     CDS             complement(119..664)
                     /locus_tag="PC466_003609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH peroxidase"
                     /protein_id="HDF2770959.1"
                     /translation="MKKFVCTVCGYIHEGDAAPAQCPVCKVGADKFEEMKGEKNWADE
                     HRIGVAQGVDEEIIEGLRANFVGECTEVGMYLAMSRQADREGYPEVGEAYKRIALEEA
                     EHAAKFAELLGEVVVADTKENLRVRVDAEYGATDGKLKLAKKAKELGLDAIHDTVHEM
                     CKDEARHGKAFLGLLNRYFGK"
     gene            complement(782..2605)
                     /locus_tag="PC466_003610"
     CDS             complement(782..2605)
                     /locus_tag="PC466_003610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2770960.1"
                     /translation="MNLSTGNQKVSRLKKKEKPKDFKKTFKRIFMYFKKDKKITRFIF
                     LLVIIDSIISTVIPYTIGKVVDIIDIDTYSKSIFLKGIIILLSFYIIEFSVKLSKGIC
                     TARLSQSIVKEMRSNLFLKFKNLPITFFDKSSTGDIMSRVTNDVDNISTGISNSLVQL
                     ITGILNILMTFIMMFVLSPILTFCSVILIPIVMFVSNFIAKRTRVFFKQQQVELGKLN
                     AHIEEMISNINVVKSFNYERKSVNDFKEVNDRLLNISLKSQIYTSLLMPIMNVISNIG
                     FATICIIGGVLASKDIITIGVIASFLSYVRQFTRPLNELANLFNTLLSAIAGCERVFE
                     IIDEQEEQEVHNMFKSEINDNKDGNLNSHFVKGEIELKDVSFSYDSKKKILDNINLKI
                     KAGTSNAIIGETGSGKTTIINLITNFYHIDEGSIFLDGKDIYSINRNYLRTCFGVVPQ
                     EGYIFNDTVMENIRYGNLEATDEEVIYASKIANAHKFIVKMREGYSTVLSDRGEDLSE
                     GQKQLISIARAVLKNAPILILDEATSNIDIATEAKIQEAINNLTYGKTSIIIAHRLST
                     ISNCDNIIVLENGRIVESGNHKELIKLKGHYYRNILLTQGK"
     gene            complement(2618..4393)
                     /locus_tag="PC466_003611"
     CDS             complement(2618..4393)
                     /locus_tag="PC466_003611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2770961.1"
                     /translation="MKYFKKYIKKYIVLFLTAVFFLTLEAFCDLAQPTIMAKIIDIGV
                     SNKNLDYILSTGAIMIGITFLGAIFAIIRSVISARVSQHFSYDLRQDVFEKINTYSLK
                     QIDKFGRASLITRITNDINQMQQFVNGMMRVFIKSPIMCIGSLIIAIKLNLKMSIIIL
                     IAVLIIFIIILLNMKIGYRLFKNVQESTDKVNSKLRQFLSGIKVVKLFCRYDYENQSF
                     EELNDELFKNSRKATTMMSFFRPTITIIINVSIIIILLIGRHLIYSGEIKIGIIVAYV
                     NYMTRILTSLIMISHVFNVFVRAKASYERISEVLVDENEEVIEREESLDVGEKDLKFV
                     NCDIIFENVDFSYNKNTDEKILKNVSFKIEEGQNIGVIGQTGSGKTSLVNLIQKLYII
                     DKGDIKIGGRSIYSISEESLREKIGVVFQNSSVFGKSILENIVMGNEGISREDVIKSC
                     EIANANQFITKLENSYDEVLFQRGKNLSGGQRQRITIARAIAKKPQILILDDCFSAMD
                     INTETIIRKNIKEYISNLREKESKKCTVITISQKISSIIDCDKILVLDEGEVVGFATH
                     EDLLVSSPIYKKIFALQNLVSEDVN"
BASE COUNT         1481 a          800 c          397 g         1845 t
ORIGIN      
        1 tttacaagat tatagctata aaaaatataa aatacaacta ttaaaaagga gcatatcatt
       61 ataattttaa aaatcataaa tgatatactc ctaaaaatct acttaactta tattaaattt
      121 attttccaaa atatctattt aataatccta agaatgcttt accatgtcta gcttcatctt
      181 tacacatttc atgtactgta tcgtgtatag catctagtcc taattcttta gcttttttag
      241 ctaattttaa ttttccatca gttgcaccat actcagcatc aactctaact cttaagtttt
      301 cttttgtatc tgcaactaca acttctccaa gaagttctgc aaatttagca gcatgttcag
      361 cttcttcaag agctattctc ttataagctt ctcctacttc tggataacct tctctatcag
      421 cttgtctact cattgctaaa tacattccta cttctgtaca ctcaccaaca aagttagctc
      481 ttaatccttc gattatttct tcatctacac cttgagctac tcctattctg tgctcatcag
      541 cccaattttt ttcgcctttc atttcttcaa atttatcagc tccaacttta catactggac
      601 attgtgctgg tgcagcatct ccttcatgta tatatccaca tactgtacaa acaaatttct
      661 tcataattac tttcctccta aattttatat atcaaattaa attttttatt tattaagtta
      721 gtctatatat acccgcacca tataccttta aacaattttt ttaaaagttt tttctaaata
      781 cttattttcc ctgtgtcaat aatatgtttc tataataatg tccctttaat tttatcaatt
      841 ctttatgatt tcctgattcc acaattctac cattttctaa aactattata ttatcacaat
      901 ttgatatggt acttaatcta tgagctataa ttatacttgt ctttccataa gttaaattat
      961 ttattgcttc ttgaatttta gcttctgttg ctatatctat gttacttgta gcctcatcca
     1021 aaataagtat tggagcattt tttaatactg ctctagcaat acttattaat tgtttttgac
     1081 cttcacttaa atcttcaccc ctatccgata atacagtact atatccttca cgcattttaa
     1141 ctataaattt atgtgcattt gctattttac tagcatatat aacttcttca tcagtagcct
     1201 ccagatttcc ataccttata ttttccataa ctgtatcatt gaatatataa ccttcttgtg
     1261 gaactactcc aaaacaagtt ctcaaatagt ttctgttaat agagtatata tccttaccat
     1321 ctaaaaatat acttccttca tctatatgat aaaaatttgt aattagattt ataatcgttg
     1381 tttttccact tcctgtctct cctatgatgg catttgatgt gccagctttg atttttaggt
     1441 ttatattatc taaaattttc ttttttgaat cataagaaaa acttacatct ttaagctcaa
     1501 tttctccctt tacaaaatga gagtttaaat taccatcttt attatcgtta atctcacttt
     1561 taaacatgtt atgcacttct tgctcttctt gttcatctat aatttcaaaa actctttcac
     1621 atccagctat ggctgaaagt aatgtattaa atagatttgc taattcattt aaaggtcttg
     1681 tgaattgtct tacataactt aaaaaactag ctataacccc tatggttata atatctttag
     1741 atgcaagaac acctcctata atacatatag ttgcaaatcc tatattacta atcacattca
     1801 taataggcat taaaagagaa gtgtaaattt gcgatttaag ggaaatattt agaagtctat
     1861 cattgacttc tttaaaatca tttacagatt ttctttcata attaaaagat tttactacat
     1921 ttatgtttga tatcatttct tcaatatgtg catttagttt tcccaactca acttgttgtt
     1981 gcttaaaaaa aactctagtt ctctttgcaa taaaattact cacaaacatt actatcggta
     2041 ttaatattac actgcaaaat gttaaaattg ggcttaatac aaacatcata ataaaagtca
     2101 tcaatatgtt taagattcct gtaattaact gtactaatga atttgatatt cctgtactga
     2161 tattatcaac atcatttgtc actctactca taatatctcc agtagaactt ttatcaaaaa
     2221 aggttattgg tagattttta aattttaaaa ataaattact tctcatttct ttaactatac
     2281 tttgagataa tctagctgta catatcccct tagacagttt aactgaaaac tcaattatat
     2341 aaaatgaaag taaaataatt attcctttta agaaaatgga ttttgaataa gtatcgatat
     2401 ctattatgtc aactaccttt ccaatagtat atggtattac agttgatata attgaatcaa
     2461 ttattactag caaaaaaata aatctagtaa tcttcttatc ttttttaaag tacataaaaa
     2521 ttcttttaaa cgttttttta aaatctttag gcttttcttt tttctttaat ctactgacct
     2581 tttgatttcc agtacttaag ttcaatatac ttcctcctta atttacatct tcacttacta
     2641 aattctgcaa cgcaaaaatt tttttataaa ttggagaact aaccagtaaa tcttcatgtg
     2701 tagcaaatcc aaccacctca ccctcatcca agactaaaat cttatcacag tcaattatag
     2761 aactaatctt ttgtgaaata gttattacag tacatttctt actttccttt tctcttaaat
     2821 tacttatata ctcttttata ttctttctta taattgtctc tgtattaata tccattgcac
     2881 taaaacaatc atcaagaatt aatatttgtg gttttttggc tatagctcta gctatagtaa
     2941 ttctttgtct ctgtcctcct gataaatttt tacccctttg aaataaaacc tcatcataag
     3001 aattttcgag tttagttata aattgatttg catttgctat ctcacatgat tttataacat
     3061 cttctctact tataccctca tttcccataa ctatattttc tagtatactt tttccaaaca
     3121 cactgctatt ttgaaatact acacctattt tttcccttaa actttcttca gaaatactgt
     3181 atatactacg tcctccaatc ttaatatcac ctttatcaat tatatataat ttttgaatta
     3241 aatttactaa agaagtcttt cctgaaccag tttgaccaat cacaccaata ttttgacctt
     3301 cttctatttt aaaggatacg ttttttaata ttttttcatc tgtatttttg ttatacgaaa
     3361 aatctacatt ttcaaaaatt atatcacaat ttacaaactt taaatctttt tctccaacat
     3421 ctaaactttc ttctctctca attacttctt cattctcatc aaccaaaacc tcacttattc
     3481 tctcataaga tgcttttgcc ctaacaaaaa cattaaaaac atgtgaaatc attataagag
     3541 atgttaatat tctagtcata tagtttacat aagcaactat aatcccaatt ttaatttctc
     3601 ctgaataaat taaatgcctt ccaatcagta atattattat tatggaaaca ttaatgatta
     3661 ttgtaattgt cggtctaaaa aatgacatca tagttgtagc ttttctacta tttttaaaaa
     3721 gttcatcatt taactcttca aagctttggt tctcataatc gtatctacaa aatagtttaa
     3781 ctacttttat tccacttaaa aactgtctta attttgaatt tactttatct gtactttctt
     3841 gtacattttt aaataatcta taccctatct tcatattaag caatattata ataaatataa
     3901 ttaaaactgc aattagaata attattgaca tctttaaatt taattttata gctataatta
     3961 aacttcctat acacattatt ggtgacttta taaaaactct catcattcca ttaacgaatt
     4021 gttgcatttg attgatatca ttagtaattc ttgttattaa cgaagctcta ccaaatttat
     4081 ctatttgttt taatgagtat gtatttatct tttcaaatac atcctgtctt aaatcataag
     4141 aaaaatgctg agaaactctt gccgagatta cacttcttat tattgcaaat attgcaccta
     4201 aaaaagttat acctatcatt atagctcctg ttgatagtat gtagtctagg ttcttatttg
     4261 aaacccctat atctattatt tttgccatta tagttggttg agctaaatca caaaaagctt
     4321 ccaatgttaa aaaaaatact gctgttagaa ataatactat atattttttt atgtattttt
     4381 taaaatactt cattcaatca tcccttcata gaattttctc attaccaaaa gtatatcata
     4441 atggctaatt taattgatta tatcaattat aaatatttga tttattatta atttttatac
     4501 catatatttt ataaattatt tgt
//
LOCUS       DAMJYN010000171         4510 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.177, whole genome shotgun sequence.
ACCESSION   DAMJYN010000171 DAMJYN010000000
VERSION     DAMJYN010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4510)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4510)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4510
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.177"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            148..1623
                     /locus_tag="PC466_003612"
     CDS             148..1623
                     /locus_tag="PC466_003612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HDF2770962.1"
                     /translation="MDSEFANAVELSYECAPLLESLKEYSEKDIACFDVPGHVKNRGV
                     AILNKYLGESLMKMDINSSPTMDNVSAPNGIIKNAQDLLAQAYMADEAFFITNGTTQA
                     IHAMILSVIKPGEKVLLPRNIHKSVINALILCGGIPIFIQPEFDEKLGISLNITLEKV
                     RTEIEKDCNIKALFFLNPTYYGVCADLESIIELCHKNNVLVLVDEAHGAHFPFHLDLP
                     PSAISLGADMVAVSIHKTGGALTQSSALLLNRDNVSFEKVLQSINMLQSTSASYLLMA
                     SIDGARVNLVENGEKQLSKALNLSRYAKSKLNKIDGIKVLSTEILKQKGVKFIDETKL
                     CINVKELNLTGFEVYDLLYKNFSIQVELGDSYNILALVSIGTNKSDIDRLVKALSIIA
                     KIYRKESTLNEFNMVQINPIIKLNPREAFYAPKESVEINSCIDRICGESIMAYPPGIP
                     IIAPGELITEEIMEYIIFLKNSNAYLTDVQDKNLDRILVIK"
     gene            1710..2123
                     /gene="speD"
                     /locus_tag="PC466_003613"
     CDS             1710..2123
                     /gene="speD"
                     /locus_tag="PC466_003613"
                     /EC_number="4.1.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylmethionine decarboxylase"
                     /protein_id="HDF2770963.1"
                     /translation="MKFETLGRHILVEYYNCDENVLKDPRLIENFMNDSALNAKATIV
                     DSVFHHFNPWGVSGAVIIAESHLTIHTWPEYGYAAADFFTCGDIDPWKSFELLEQLLK
                     SERSESTEIPRGLTTKIKKYSKKDLGKITHKPEAV"
     gene            2153..3004
                     /gene="speE"
                     /locus_tag="PC466_003614"
     CDS             2153..3004
                     /gene="speE"
                     /locus_tag="PC466_003614"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HDF2770964.1"
                     /translation="MELWYTEEWTENVRFSIKVNKHLFEGKSQFQRIDVFDSDEFGKF
                     LTIDGLMMVTYKDEFIYHEMITHVPMATNLNIKKVLVIGGGDGGTVRELSRYPQIEKI
                     DMVEIDKMVVDVSKEYMDICSCKLDDKRVSLYFEDGVNFVKCAHDKSYDLIIVDSTDP
                     IGPGEGLFSTDFYKDCYRILTDDGILVNQSESPYFDFNAKEMKRANKKLKQIFPISEV
                     YQAHIPTYPSGHWLFGFASKKLNPVKNQDRNGWEKLSLKTKYYNSDIHLGSFMLPQYV
                     KEMLDEE"
     gene            2994..3872
                     /gene="speB"
                     /locus_tag="PC466_003615"
     CDS             2994..3872
                     /gene="speB"
                     /locus_tag="PC466_003615"
                     /EC_number="3.5.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatinase"
                     /protein_id="HDF2770965.1"
                     /translation="MKNNFYHMNTFMSMDKNYEESNLIVFGVGFDGTTSNRPGARFAS
                     SSMRKEFYGLETYSPFLDLDLEDYNICDYGDLEISVGSTEQVLKEIYQETYKIVRDSK
                     VPFMIGGEHLVTLPAFKAVHEKYNDIYVIHFDAHTDLREEYNNSKNSHATVIKRIWDI
                     VGDNKIFQFGIRSGTKEEFKFATEEKHTYMEIGGIDTFENIVNMLNGKNIYLTIDLDV
                     LDASVFPGTGTPEPGGVNYREFQEIFKIIKNSNINIVGCDIVELSPDYDTTGVSTVIA
                     CKILRELCLIISDKIK"
     gene            complement(4052..4252)
                     /locus_tag="PC466_003616"
     CDS             complement(4052..4252)
                     /locus_tag="PC466_003616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000809131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HDF2770966.1"
                     /translation="MKNGIVKWFNNEKGFGFISVEGEDDVFVHFSAIQNDGYKTLEEG
                     EKVSFDITQGNRGPQAENVNRI"
BASE COUNT         1797 a          502 c          769 g         1442 t
ORIGIN      
        1 agtaacttca aaaaaacact tgtaaaaatg ctggaatgtt aatataataa atatcatgag
       61 tttaataaaa gtaaaaataa aaaatagaaa taataaataa taaatattaa aaatatttga
      121 atatagagag gagatgaatt tgaaatcatg gatagcgagt ttgcaaatgc agttgaatta
      181 agctatgagt gtgctccatt attagagtcg ttaaaggaat actcagagaa agatatagct
      241 tgttttgatg ttcctggaca tgtaaaaaat agaggtgtag ctatattaaa taaatatcta
      301 ggtgaaagtc tcatgaaaat ggatataaat tcatcaccaa ctatggataa tgtatctgcg
      361 ccaaatggga ttataaaaaa tgcacaagat ttgctagcac aagcatatat ggctgatgag
      421 gcattcttta taacgaatgg cacaactcaa gcaatacatg caatgatttt gagtgttata
      481 aaaccaggtg aaaaagtatt acttccaaga aatatacata aatcagtaat aaatgcgtta
      541 atactttgtg gaggaatacc aatatttata caaccagaat ttgatgaaaa actaggtata
      601 agtttaaata ttactcttga aaaagttaga acagagatag aaaaagattg taatataaaa
      661 gcattatttt tccttaatcc aacttactat ggagtttgtg cagaccttga gagtattata
      721 gaactatgcc ataaaaataa tgttttagtg ttagttgatg aagctcatgg tgcacatttt
      781 ccatttcatt tagatttacc tccttctgca ataagtttag gagctgacat ggtagctgta
      841 agtatacata aaactggagg agcattgaca caatcttcag cactcttatt gaatagagat
      901 aatgtaagtt ttgaaaaggt tcttcaatca atcaatatgc tacaatcaac atcagcatct
      961 tatttgctta tggcaagtat agatggtgct agagttaatc tagttgagaa tggtgaaaag
     1021 caactgtcaa aagcattaaa tctatctagg tatgcaaaat ctaaattgaa caaaattgat
     1081 ggaataaaag ttttatctac agaaatattg aaacaaaaag gtgttaaatt tatagatgaa
     1141 acaaaattgt gtataaatgt aaaagaatta aatttgactg gatttgaagt atacgattta
     1201 ttatataaaa atttttcaat tcaagtagaa ttgggagatt catataatat actggcactt
     1261 gtgtccattg gaacaaataa atcagatata gatagattag taaaagcact ttctataatt
     1321 gcaaagattt atagaaaaga atcaacatta aatgaattta atatggttca aataaatcca
     1381 attattaaac ttaatccaag agaagctttt tatgcaccaa aggaaagtgt agaaatcaat
     1441 tcatgtatag atagaatttg tggagaatca ataatggcat atccaccagg tataccgatt
     1501 attgctccag gagaattgat aacagaagaa attatggagt atattatttt cttaaaaaat
     1561 agcaatgcgt atcttacaga tgtacaagat aaaaacttag atagaatact agtaataaaa
     1621 taaattactt tattttgcaa gggcaagtgt ttgttaagta gagtttatca aatagaactt
     1681 attaaaagta taaaggagtt ggggttgaaa tgaaatttga aacactagga agacatatac
     1741 tagtagaata ctataattgt gatgaaaacg tacttaaaga cccacgtctt atagaaaatt
     1801 ttatgaatga ttcagcatta aatgcaaaag cgacaattgt ggattctgta ttccaccatt
     1861 ttaatccttg gggggtttca ggagctgtta taattgctga atctcatttg acaatacata
     1921 catggcctga atatggttat gcagcagcag atttttttac ttgtggtgat atagacccat
     1981 ggaaaagttt tgaattatta gagcaacttt taaagtctga aagaagcgag tctacagaaa
     2041 ttccaagagg cttaactaca aaaattaaaa aatattcaaa aaaagattta ggtaagatta
     2101 ctcataaacc agaagcagta taaaacatac aagagaaagt gaggattatt atatggaact
     2161 ttggtataca gaagaatgga cagaaaatgt aagattttct ataaaagtaa ataaacatct
     2221 atttgaagga aagtctcaat ttcaaaggat agatgtattt gatagtgatg aatttggaaa
     2281 atttctaaca atagatggat taatgatggt aacatataaa gatgaattta tataccatga
     2341 gatgataact catgttccta tggctacaaa tttaaacata aagaaagtat tagtcatagg
     2401 tggaggtgat ggaggtacag taagagaatt aagccgttat cctcaaatag aaaagattga
     2461 catggttgaa atagataaaa tggttgtaga tgtatctaag gagtatatgg atatatgctc
     2521 atgtaaatta gatgataaaa gagtgagttt atattttgaa gatggtgtta attttgttaa
     2581 gtgtgcacat gataaatcat atgacctgat aatagtagat tcaactgacc caataggacc
     2641 aggcgaaggg cttttctcaa ctgattttta taaggattgt tatagaatac tgactgatga
     2701 tggaatttta gtaaatcaaa gtgaaagtcc gtattttgac tttaatgcta aagagatgaa
     2761 aagagctaat aaaaaattaa aacagatatt tccaatatca gaagtttatc aagcacatat
     2821 accaacatat ccatctggtc actggttgtt tggatttgct tcaaaaaaac ttaatccagt
     2881 aaaaaatcaa gatagaaatg gatgggagaa attaagttta aaaactaaat attataatag
     2941 tgatatacat ttaggttcgt ttatgttacc tcaatacgtg aaggagatgc tagatgaaga
     3001 ataatttcta tcatatgaac acttttatga gtatggacaa aaattatgaa gaatctaatc
     3061 ttatagtatt tggtgttgga tttgatggaa ctacttctaa cagacctggg gctagatttg
     3121 caagtagctc tatgagaaaa gaattttacg gtcttgagac atatagtcct tttttagatt
     3181 tggacttaga ggattataat atatgtgatt atggagattt agaaattagt gttggaagta
     3241 cagaacaagt cttaaaagaa atctatcaag agacatataa gattgttaga gattcaaagg
     3301 taccctttat gattggagga gagcatttag ttacattacc agcctttaaa gcagtacatg
     3361 aaaagtacaa tgatatatat gtaattcatt ttgatgccca tactgatttg agggaagaat
     3421 ataataatag taaaaattct catgcaacag taattaaaag aatatgggat attgtaggtg
     3481 ataataaaat atttcaattt ggtataaggt ctgggacaaa agaagaattt aaatttgcta
     3541 cagaagaaaa acacacatac atggaaatag gaggaataga tacgtttgaa aatatagtta
     3601 atatgctaaa tggaaagaat atttatctaa ctatagattt agatgtattg gatgcatctg
     3661 tgtttccggg aacaggtaca ccagaacctg gtggtgtaaa ttatagagag tttcaagaga
     3721 tttttaagat tataaaaaac tctaatataa atatagttgg ttgtgatatt gtagagttaa
     3781 gccctgatta cgatacaaca ggtgtatcga cagttatagc ttgtaaaatc ttaagagagt
     3841 tatgcttaat aatatctgat aaaattaaat agagtatttt atataaatag tatatattat
     3901 aatataagaa gttattttaa aaaagttagt ttaagtttga cgcttttcta aagtaacttc
     3961 ttatttttgt aattaaaaat aaatataata aacaacaaaa aagagccctc gatagctcct
     4021 tttctaaaat atatatattt aaattaaata attatattct atttacgttt tcagcttgag
     4081 gtcctctatt accttgagtt atatcaaagc taaccttttc gccttcttct aaagttttgt
     4141 atccatcatt ttgtatagct gagaaatgta cgaaaacatc atcttctccc tctacagata
     4201 tgaacccaaa tcctttttca ttgttaaacc attttactat tccgtttttc attataagaa
     4261 aacctccgca ttattaaaaa atacaaacta aaaaaataag tctgttctat taatataaca
     4321 taaattttaa ataaaagcaa ataaaatttt taaaaaaatt aattactttt agaatttaat
     4381 aaaaattgtt aaattataca gtgagaagta ttgtaaaatt tgacgaaaat gtaaatgtag
     4441 ataataaatt taatgtcaaa aaatgcaaca aaaaggtatg taagtaaaaa gtaaaattaa
     4501 aatatataat
//
LOCUS       DAMJYN010000172         4508 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.178, whole genome shotgun sequence.
ACCESSION   DAMJYN010000172 DAMJYN010000000
VERSION     DAMJYN010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4508)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4508)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4508
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.178"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     repeat_region   124..1078
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=323..351
                     /rpt_unit_seq="atttacataccacatagttaatataaaac"
     gene            complement(1274..1513)
                     /locus_tag="PC466_003617"
     CDS             complement(1274..1513)
                     /locus_tag="PC466_003617"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770967.1"
                     /translation="MECYLKRTLIIFSKAFLSISFKTRKYLFIVIFILVCPNLSEMIF
                     ILVPARRRIIRIDNIVSIYKYVGVLKLINYSILIL"
     gene            1725..2996
                     /locus_tag="PC466_003618"
     CDS             1725..2996
                     /locus_tag="PC466_003618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HDF2770968.1"
                     /translation="MLKVLKGNIIFTKTSETFTVFENSYIILEKGKVKGIFKEIPKEY
                     KNLKVVDYTDKLIIPGMNDLHAHASQFKNLGMAMDKELLPWLETYTFPEESNYKDIEY
                     ATKMYKKFVKELWKSGTTRIAVFATVHKEASMKLMDIFKEVGLGAYVGKVNMNMNCPD
                     TLLENTQDSIADTEEIINKYSDTDSIVKPIITPRFIPSCTSELLKGLGDLCLKYNIPM
                     QSHLSENYDEIEWVRSLEPESKFYGDAYNRYNLFGQTPTLMAHCVHCSQDEIDLMREN
                     NVMAVHCPASNFNVGSGAMPIRKLIDNNIRLALGSDISGGHTLSIFKAMVSAIQLSKL
                     YWVNSGKKYNFLSLSEAFYIATKSGGSFFGKVGSFEEGYDFDALIIDDSNLNHDNYSI
                     LERLERFIYVGDDRNIIHRYVCGKLIEEPNI"
     gene            complement(3635..4390)
                     /locus_tag="PC466_003619"
     CDS             complement(3635..4390)
                     /locus_tag="PC466_003619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1835 domain-containing protein"
                     /protein_id="HDF2770969.1"
                     /translation="MAHICFEDICYLLLKEAMKLKLIPHNKIVLFEDDLSIGNIFDVN
                     NYELRENIFKIRNVFENNPKLLFKPDLLEDRKLSKCRNIIIWCANNPKDLCGVYYVVS
                     KFQDKNIKIALVDEKKTEDALIRYSFTSEMSPEDFPFFLDKTLEIGFNEKLEFKNKWD
                     VLVKENSIFRALVGNEIKSVEETYFDKYILRNISDKWQPLIEVVANCMFEDEMRVKDW
                     FILWRLEKMASLKIVKIKGSKGDFYSDKEIRKV"
BASE COUNT         1725 a          631 c          495 g         1657 t
ORIGIN      
        1 atcattaaaa ctaaagtcaa tgttatctgg taattattta ctacaaatga taaaaaataa
       61 ttatatttta aagtagaaaa tgctgtataa attattgggg tattttacct atacttgttg
      121 caaatttaca taccacgtag ttaatataaa acaaatttca agcgattgga caacgaataa
      181 aaattgcaat ttatatatca tgtagttaat ataaagcata tttgtgtcga tatatagttc
      241 taactaagta taagatttac atacctcata gttaatataa aacaatgtgt ccgaattgga
      301 cacatagaaa ggaaaagtaa aaatttacat accacatagt taatataaaa ctatgcttat
      361 atattatgtt tattctgttg tttctaaaat ttacatacca catagttaat ataaaacgat
      421 tttttcatgc ggaggaaaat tgatgtgggg acatatttac ataccacata gttaatataa
      481 aacagataat ctaggcacac atacaatgcg caaaacttta tttacatacc acatagttaa
      541 tataaaacat tcagacgata taggcgcagg agctaagtat tctgaaattt acataccaca
      601 tagttaatat aaaaccagca cgccaagtat aagtaaaact tccactatca ccatttacat
      661 accacatagt taatataaaa ctaaatgttg ctccgtaacc taaaaacata atgctccaat
      721 ttacatacca catagttaat ataaaacgtg aaagaaaaat taatatgcta tttacatttt
      781 acaaatttac ataccacata gttaatataa aaccattcca caatttatac aattttttct
      841 gttctaaaac atttacatac cacatagtta atataaaact cttcttatct tccagttgca
      901 aaatctatgc ttgacctatt tacataccac atagttaata taaaactagt ttgagtggta
      961 aaagtacgaa gtacccctct ttaatttaca taccacatag ttaatataaa acatatgtaa
     1021 ttcaccgttt taaattatag ataaattaaa tttacatacc acatagttaa tataaaaccc
     1081 caaaataaac taagtatttt cagtacttac acacatacaa ctctctcaaa tttgcagtga
     1141 accatgagta gtgcaattga taacatttat catacaccct caatccctta cattgcaact
     1201 gttaaaccct actttatcaa aaatatcgct cactgcaaaa tttatatatt tttattatat
     1261 cataaaattc aaactataaa attaaaatgg aataatttat caatttaaga acacctacat
     1321 atttgtaaat acttactata ttatctattc taataattct tcttctagct ggaactaata
     1381 taaaaatcat ctctgaaaga ttaggacata ctaatataaa aataactatg aatagatatt
     1441 ttcttgtttt aaacgatatg gataaaaaag cttttgaaaa tataatcaaa gttctcttta
     1501 aataacattc cattttatgt aagtaagcat tatatttttc ttaaatgtca cttaagtgtc
     1561 agttatatat aataatagta aacaactgta tttcactaat atttgctatt atctaatagt
     1621 atttatagtt tagatttgat ataatacatg tggtaaaatt ttgatttgta aaacaaaatt
     1681 ttacctacat atattaaaac aaatttaaaa ctaaggagac ctatatgtta aaagtattaa
     1741 aaggaaatat aatttttaca aaaacttcag aaactttcac agtatttgaa aatagttata
     1801 ttatactgga aaaaggtaaa gtaaagggaa tatttaaaga gatacctaag gaatacaaaa
     1861 acctaaaagt agtagattac actgataagc ttataatacc tggtatgaat gacctccatg
     1921 cccatgcctc tcaatttaaa aatcttggaa tggctatgga taaagagctt ttgccatggc
     1981 ttgaaactta tacatttcca gaagagtcaa attataaaga tatagaatat gcaacaaaaa
     2041 tgtataaaaa atttgtaaaa gaactttgga aatctggaac tacaagaata gcagtgtttg
     2101 caacagtaca taaagaagcc tctatgaaac ttatggatat attcaaagaa gttggtcttg
     2161 gagcatacgt tggtaaagta aatatgaata tgaattgccc tgatacttta ttagaaaaca
     2221 ctcaggattc tattgctgat acagaagaaa ttataaataa gtatagtgat acagattcta
     2281 ttgtaaaacc aataataaca cctagattta taccaagctg tacaagtgaa cttttaaaag
     2341 gtttaggaga tttatgttta aaatataata ttcctatgca atcacactta tctgaaaatt
     2401 atgatgagat tgaatgggtt agaagtctag aacctgaatc taaattctat ggagatgcat
     2461 ataatagata taatttattt ggtcaaactc ctactttaat ggctcattgt gttcattgtt
     2521 ctcaggatga aatagattta atgagagaaa acaatgttat ggcagttcac tgtccagctt
     2581 ctaactttaa tgttggtagt ggtgctatgc ctatcagaaa attaatcgat aataatatta
     2641 gattagcact tggatcagat ataagcggtg gacatacatt gtcaatattt aaagcaatgg
     2701 tatctgcaat acaattatct aaattatatt gggttaattc tggtaagaag tataatttct
     2761 tatctttatc tgaggctttt tatattgcaa ccaaaagtgg tggaagtttc tttggaaaag
     2821 ttggtagctt tgaagaaggt tatgattttg atgcattgat tattgatgat tcaaatttaa
     2881 atcatgacaa ttattctata cttgaaagac ttgaaagatt tatctatgtt ggtgatgata
     2941 gaaatatcat tcatagatat gtatgtggaa aactaattga agaacctaat atataattat
     3001 aataaaaatt ttaattatat attatggtta atttatgcaa ctataattaa taaaagagta
     3061 tattttaaat ctaaaagcta taggttgaaa catactcttt ttattttgtt tatttatagc
     3121 tttagttatt aatcatatat aaatctacaa aacgtattcc tagtaactta tattttttga
     3181 tatctacaat cataagacta tattattgga ttcatacctc aaaaatattg ccttctgaac
     3241 attattatat tcaaagttat gttaatttac aatgatatat ctaacatgta ttgattaaaa
     3301 aaaattaaaa cttgcttttc atctcctata tctaaagaag tggcatttag aataaactat
     3361 tgtaatatta aagttgaaat tttctagttt atttactcta tagcaccata ttttaatact
     3421 attaagtaaa aatgtagtta aaatatatac taatatccct gaaataagta tttctttttt
     3481 atttagcaca cttattcgta aggtattagt tattatattt tcaaattata gaataaatat
     3541 tatacttatt gctaattata atattaatac tgttaagata tttttcttca tagttatacc
     3601 cattatttaa tacaatttat tataaattca atttttaaac ttttcttatc tccttatcag
     3661 aataaaaatc ccctttactt ccttttattt ttactatttt taaacttgcc atcttctcta
     3721 atctccaaag tataaaccaa tcttttacac gcatttcatc ttcaaacata cagtttgcaa
     3781 ccacttcaat taaaggttgc catttgtcac tgatatttct taatatatat ttatcaaaat
     3841 aagtttcttc aacactttta atttcgttac ctactaatgc tctaaaaata gaattttctt
     3901 taactaacac atcccattta tttttaaatt ctagtttttc attaaagcca atttctagtg
     3961 tcttatctaa aaagaatgga aaatcttctg gagacatttc actggtaaat gaatatctaa
     4021 ttagagcatc ttctgtcttt ttttcatcta ctaatgcaat ctttatattt ttatcttgaa
     4081 acttactcac tacataatat actccacaca aatcttttgg gttatttgca caccatatta
     4141 ttatatttct acattttgat aatttcctat cttctaacaa atctggcttg aataatagtt
     4201 tcggattatt ttcaaaaaca tttctaatct taaaaatatt ttctcttaat tcgtagttat
     4261 ttacatcaaa aatattacct attgataaat catcttcaaa taatacaatt ttattatgtg
     4321 gtattaactt taacttcatt gcttctttta ataacaaata acaaatatcc tcaaagcata
     4381 tatgtgccat aaaattcacc tcttttaaaa ttaacaattt attttattat aatatataaa
     4441 ctgtaattat caaacacttc taatctccta tattttcata ttaatgtaat atctttttta
     4501 ttaatact
//
LOCUS       DAMJYN010000173         4319 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.179, whole genome shotgun sequence.
ACCESSION   DAMJYN010000173 DAMJYN010000000
VERSION     DAMJYN010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4319)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4319)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4319
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.179"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(732..1142)
                     /locus_tag="PC466_003620"
     CDS             complement(732..1142)
                     /locus_tag="PC466_003620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770970.1"
                     /translation="MKIKKSLISAMMVSAMVLGGTGAVFANGNDSSNIALPKLESLIK
                     SGITDPTELEKYGVEHYTYEEYAKHIQELKDYAKDPNAVKDVSQKDLEETIKKMEQEL
                     EKIKTEGLKIMKPITIENEDGSQISIAYNYAAID"
     gene            complement(1358..2740)
                     /locus_tag="PC466_003621"
     CDS             complement(1358..2740)
                     /locus_tag="PC466_003621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HDF2770971.1"
                     /translation="MFIKLLEMSFTSGVLLLIVIFIRACLFKKLPKKVFVLLWLIVLF
                     KLLIPVSLNSGFSIYSIIESTFDVELGNTSTENYTLKKASDSTGKNNSDEFEIMSNIE
                     NIMMLEMLGILSFIVTIMFSILLCFRYFKIINLFKTSIHIKNHEFIKKWMCKNSRFRR
                     FIVCISEFTRTPLTSGILKPRIILPKQMNYANNQTLDFVLTHEMVHINSFDNLLKLFM
                     LVALVVHWFNPLVWVMFFLLNKDIEFSCDEKVMSILGEEYRADYATTLISLAEENNPF
                     SMTICSGFGKTKIEKRIVNIMKFKKSTYVTFLVSTVLVCGTGLVFATENKEINEVESF
                     GLTKNEQSDKSGFSISSKSTDLYSPKVESDILVSKAKSDGETHFSTAKVSVIEFREHE
                     ESSMSKVTNSENSEETYVNKSSNSKDVLYTDSGEVSIEQSNYNDNRFVISRKGNLLAV
                     NKEQYRTWIE"
     gene            complement(2751..3110)
                     /locus_tag="PC466_003622"
     CDS             complement(2751..3110)
                     /locus_tag="PC466_003622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF2770972.1"
                     /translation="MEIKLFDSELKVMEVLWERGESKAGELVKILKEETGWNRNTTYT
                     VIKKLVSKGAIERIEPNFVCKALISKEEVQKQETETLINKMFGGSSEKFLSAFINKEN
                     LSSDEITKLKQIVEKLK"
     gene            complement(3315..4094)
                     /locus_tag="PC466_003623"
     CDS             complement(3315..4094)
                     /locus_tag="PC466_003623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HDF2770973.1"
                     /translation="MVSRQELKRVSKAQLSGNWGICAISMAVYIALIVLISIVGLPFE
                     PLTTIVVAVIAFCVSAGFTCMFLKITKDEKVKIGDIFVSGRIYLRSFGFYLFESIIVY
                     IYSFIITIIGAFLSFGVLLTSGAIEYLSSDNVGIGTIISTGITLVLIILVLMLPVYIL
                     LLYVSQATFLICEDKDNMGVFKSMGASLDMMKGNVLKLFVLNFSFIGWYILSIATLGI
                     GLLWLIPYVGVTNCNFYRQLVKENPDVEDILLDKEKSYTMY"
BASE COUNT         1519 a          703 c          400 g         1697 t
ORIGIN      
        1 tatctatttt tttctggtat tcttatctac tattatccgt atatttattt tatgattact
       61 cttttaacct accccctata ctttatagta atatgttttt aacctttttc attattccca
      121 atatgcttta taactacaaa tactctcccc ccttaaaaat aataataaaa ttaatcaata
      181 aatttataat catattatta ctctatgtat taagcaatta ctatgccaat aaattttgat
      241 ttttttaaac aaatcttaaa aatcctaaaa tgctaatttt ctttaacttt taatgaatct
      301 aatagataat atttaatttt cgttatattt ttcagaatgt ttcaattatt atttttaaga
      361 aaaaaaaata atgttaacat ttcttaacat acattaaaaa atgttaacat tataaatttg
      421 gtttaatact tttactttga ctcgatttac ttttattcta cttcttactt tatttttaac
      481 ttagacttta tttttttatt acttatttga gtcttattta ttttattctc actccatatg
      541 ttcaattaca tttgtctaaa ttctttgata cttttattac ataattttaa caagcttaag
      601 tgttatttgg gtagtgcagt tgataattat ttaaataatc atcaactgca tgtttatatc
      661 attacagtag cttaatgtat ttaatcatac ttacttagga ttttgaaata tcttagagat
      721 tatatttaac attagtcaat tgctgcataa ttgtaagcaa ttgaaatttg agacccatct
      781 tcattttcta tagtgatagg cttcataatt tttaatcctt cagtttttat cttttctaat
      841 tcttgttcca ttttcttaat tgtttcctca aggtcttttt gacttacatc tttgactgca
      901 ttagggtctt tagcatagtc ttttaattct tgaatatgtt tagcatactc ttcataagta
      961 taatgctcaa caccatactt ttccaattca gtagggtcag ttattcctga ttttattaga
     1021 gattcaagtt taggtaaagc aatattagat gaatcatttc catttgcaaa tactgctcca
     1081 gttcctccta gtaccattgc agataccatc attgcactta taagggattt ttttattttc
     1141 ataaccaatc ttcctttctt agagatttat ttgggtagtg tagtttaaaa tgactattgc
     1201 aatagttatc aaccacatct ttagactacc atagtagtca tatttgtgtc aagtcttttt
     1261 aaaaaacttt tcaataaaaa atactatctc aaaacaaaat taattatttt gagatagtat
     1321 tttaattcta aatcttttat attactaaga tttatggtta ctctatccat gttctatatt
     1381 gttctttatt aactgctaac aaattccctt ttcttgatat gacaaagcga ttatcattat
     1441 agttactttg ctcaattgaa acttctcctg aatcagtata aagtacatcc ttactattac
     1501 tagatttatt tacatacgtt tcttcactat tctcagaatt agttactttg ctcatagatg
     1561 attcttcatg ctctctaaat tcaattacag atacttttgc cgtactaaaa tgagtctctc
     1621 catcactttt agctttacta acaagaatat cagattctac tttgggagaa tataaatcag
     1681 ttgatttact acttattgaa aatccacttt tatcactttg ttcatttttt gttaaaccaa
     1741 aagattcaac ctcattaatc tctttatttt ctgttgcaaa aacaagacct gtcccacaaa
     1801 ctaatacagt tgaaactaaa aaagtaacat aagttgattt tttaaatttc ataatattaa
     1861 ctattctctt ttctattttt gtctttccaa atccactaca tattgtcatt gaaaatggat
     1921 tattctcctc tgctagactt attagtgtgg ttgcataatc agccctatat tcttcaccaa
     1981 gtatactcat aaccttttca tcacaactaa attctatgtc tttatttagt aaaaaaaaca
     2041 tcacccaaac taagggatta aaccaatgga caacaagagc tacaagcata aataacttta
     2101 acagattatc aaagctatta atatgaacca tttcatgagt taaaacaaag tctaaagttt
     2161 gattattagc ataattcatt tgctttggca aaataattcg tggttttaaa ataccagatg
     2221 taagtggtgt cctagtaaat tcagatatgc aaacaataaa tcttctaaaa cggctattct
     2281 tacacatcca ttttttaatg aactcatgat tttttatatg aattgaagtt ttaaaaagat
     2341 taattatttt aaaatatcta aagcataaaa gtatgctaaa cataatagta actataaaag
     2401 acaaaatgcc caacatttcc aacatcataa tattttcaat attagacatt atttcaaatt
     2461 cgtcagaatt gtttttacct gtagagtcac tagctttctt aagagtataa ttttctgttg
     2521 atgtattacc caattctaca tcaaaagtcg attcaattat actataaata ctaaaaccag
     2581 aatttaaact tactggtatt agaagtttaa ataaaacaat caaccacaat aatacaaata
     2641 cctttttagg taatttttta aataaacatg ctcttataaa aataactatt aaaagtaata
     2701 ctccagaagt aaaactcatt tctaacaatt taatgaacat aaatcttacc tcactttaat
     2761 ttttcaacaa tttgtttgag ttttgtaatc tcatcacttg aaagattttc tttattaata
     2821 aaagctgaaa gaaatttttc tgaagaccct ccaaacattt tattaattaa agtttctgtt
     2881 tcctgttttt gtacttcctc tttgcttatt aaagctttac aaacaaaatt tggctcaatt
     2941 ctctctattg caccttttga cactaatttt tttataacgg tatacgtagt gtttctattc
     3001 catcctgttt cttcttttaa aatttttact aactctccag ccttgctttc tcctctctcc
     3061 catagaactt ccattacttt aagttctgaa tcaaataatt ttatctccat ataaaatcgc
     3121 tcctcaaata tagttatcac aatagtcatt actataataa aaaactatca tagtagtcta
     3181 tactatgtca atcatttatt ttttaataat aaaaactgtc tttttaaaaa attcttataa
     3241 aagacagttt tatcaatgtt atactttaat gtttaattaa agccatattt tatttaaatg
     3301 tataactatc tatcttagta catagtataa gatttttctt tatctaatag tatatcctct
     3361 acatctgggt tttcttttac taattgtcta taaaaattac aattagtaac acctacatat
     3421 ggaattagcc atagtagacc tattccaaga gtagctattg aaagtatata ccatcctata
     3481 aaactaaagt ttagtacaaa taatttaagt acatttcctt tcatcatatc taaactagca
     3541 cccattgatt taaatacacc catattatcc ttgtcttcac aaattaagaa agtagcttga
     3601 gaaacatata atagcaatat ataaaccggt aacataagaa caagtattat aagaactaga
     3661 gttattccag tagaaataat agtccctatt ccaacattat cacttgataa atattcaatt
     3721 gctccactag taagtaaaac tccaaatgat aaaaacgctc ctataattgt gattataaaa
     3781 gaataaatat aaacaataat tgattcaaat aaataaaaac caaaacttct taaataaatt
     3841 ctcccactta caaagatatc tcctatcttg actttttcat ctttagtaat tttcaagaac
     3901 atacatgtaa atcctgctga aacgcaaaaa gctattacag ccactacaat agtagtcaat
     3961 ggttcaaaag gtaatcctac aattgatatt aatactatca atgcaatata tactgccata
     4021 gaaattgcac atattcccca gtttccagat aactgagctt tagatactcg ttttaattct
     4081 tgccttgata ccataaaaaa cacccctttc attttataaa aaaactttta aaaatataaa
     4141 taatctttta acgtataata ttaatatatc atattttcga ctatataaga tacaattatt
     4201 caccatgttt tatcaagata tgccataatt gtattactag ttttatatag tcaacattac
     4261 caaatacatc aaataaattt gattaattat tcaacaagta ataaaataat ttctattaa
//
LOCUS       DAMJYN010000174         4276 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.180, whole genome shotgun sequence.
ACCESSION   DAMJYN010000174 DAMJYN010000000
VERSION     DAMJYN010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4276)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4276)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4276
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.180"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(130..505)
                     /locus_tag="PC466_003624"
                     /pseudo
     CDS             complement(130..505)
                     /locus_tag="PC466_003624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430377.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
     gene            complement(610..987)
                     /locus_tag="PC466_003625"
     CDS             complement(610..987)
                     /locus_tag="PC466_003625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF2770974.1"
                     /translation="MKEEILIEKLLRAELIVMEYLCKKDTLMPKKEIVKEIKQIYGWH
                     KSTIKILLKRLVAKRYLARYIINFQYHYKIIIDNKEYYTFKKKVLKSSKSIKIMRSLT
                     TTHKNVSKEKLDLLDEYYRNLKE"
     gene            1793..2287
                     /locus_tag="PC466_003626"
     CDS             1793..2287
                     /locus_tag="PC466_003626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HDF2770975.1"
                     /translation="MKNKKGFTLVELLVVIAIIGILAIIALPALFKNIEKAKIAKLEA
                     DISAIKSASLSYYADESKYTDGGMISWVKKDGKIIINGGFKDDPLADKIENLGMPYNG
                     SYLLMSSPGHEKYLELSILPEGEISKSGLDKLKNDYGNLIDITNDQNKINIVIKLLNN
                     KSNT"
     gene            2684..2834
                     /locus_tag="PC466_003627"
                     /pseudo
     CDS             2684..2834
                     /locus_tag="PC466_003627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897489.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(3310..3498)
                     /locus_tag="PC466_003628"
     CDS             complement(3310..3498)
                     /locus_tag="PC466_003628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDF2770976.1"
                     /translation="MTKYDFNFKLKVAKFYLNREGRDILIVKQYGVYDHSQVERWVNI
                     LGEGALKIKKFSILYGSS"
     gene            3660..4010
                     /locus_tag="PC466_003629"
     CDS             3660..4010
                     /locus_tag="PC466_003629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3796 domain-containing protein"
                     /protein_id="HDF2770977.1"
                     /translation="MIQKKIFMGFCGFLGFLSLRYFSSGNVTDLTYIGFFAFFSNFII
                     AKINGDKADERYVQDEKAAMAFTGQLAIIELFILWCITIVSRNVELMCVLLSITYAIT
                     LNVYAIKLYILEEK"
     gene            4012..4212
                     /locus_tag="PC466_003630"
     CDS             4012..4212
                     /locus_tag="PC466_003630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2770978.1"
                     /translation="MPKFICNLKKYRQLKELTQEQLAEKVGVRRETIMRLEAGKYNPS
                     LKLAIDISKIVDTPIDELFIFD"
BASE COUNT         1528 a          516 c          480 g         1752 t
ORIGIN      
        1 atttatataa ataaaataca aacttatttc atttttttaa catgttcaga ataataaaca
       61 aaatgaatgt agaaaaagtt ataatttcat accttcattt tatttattat gtatctagct
      121 gtcattttct tattttaaat tcttaaaata ttcttctaat aaatttaaaa tatcaccatc
      181 tacttcatca tccttactac atagtgctga cattaaactt aatattgaat ttttatgtgt
      241 attctttaaa aattcttttg tttaaaatct ctgatattat ttttctttta ctaatacatt
      301 atagtgtgta cgcttatcta ttttctccgt ttctaaaaac tctcttcttt agtaatcttt
      361 ttaatactgt aaatatagtt gtatctttcc attcatattt ttgttccata gacttggtga
      421 tttctcttga tattaatacc ttttctgatt cccaaatata tctcataact tttaattccg
      481 cttctggtaa tttactaatt ttcatagtat acatcccttt accaatttat gtatatgtta
      541 aattctatat caataaagtt ttacaaacaa aagaattaag gtaaataatt acattcgatt
      601 tttactatat cattctttta aatttctata atactcatct aataggtcta acttctcttt
      661 acttacattt ttatgtgtag tggtaagtga acgcattatt tttatgcttt tactagattt
      721 tagtaccttt ttcttaaaag tataatattc tttattatct attattattt tataatgata
      781 ttgaaaattt ataatatatc tagccaaata ccttttagca actagccttt ttagtagtat
      841 ttttattgta cttttatgcc atccataaat ctgttttatt tcttttacaa tttctttttt
      901 aggcattaga gtgtcttttt tacataaata ctccattact attaattctg ctcttaataa
      961 tttttctatt aatatttctt ctttcaattt atgtcacttc cttaattctt ctaacttaaa
     1021 ttaataatag gagcttttta agacaaaaac tagaggtaag ttttaccaaa tattctacat
     1081 atttagtctg tttttttaaa cgtaaaataa tattcatata tatatatttg tttaatttgc
     1141 aaacaatgct accaaacaat aaatagctct attgtattat tttagttgta gaatagcact
     1201 aaatcgttag aatcaaagaa atttagtagc acaaaactat ataggctaat gcttataaaa
     1261 taaattataa gttatgttaa caagttacta aaagcatatt ttatttttgt ttttatgaaa
     1321 gttttttagg tatgtaataa tatatatctt ttaaaaatat gtattcatgt atacatattt
     1381 tgacttatta tactgataat tcatataatt attttgattt tatagataca cagttagatg
     1441 attttataat agagcataaa aaaaatgtag tataatcttg tttatatcaa gttatggtat
     1501 tggtaagtaa gtataattaa atagacatta ttttctgggt cctcttttta ttttcatctg
     1561 cttttaaata atattattga cattgatatg actgtagttt tctttatttt aatccattgc
     1621 ttatatcttt tctaacaaga aatgtcattt taaatcattt ctataaattg taaaataata
     1681 gtatatttgt catagaaagt gatttttttg tctatatatg gtaaaatata gaaagtagaa
     1741 atcaacaaaa taaaaattta tatattatta attttatatg gaggggaaat aaatgaaaaa
     1801 taaaaaagga tttactctag tggaattatt agtagtaatt gctataatag gaatattggc
     1861 aataatagca cttccagcat tatttaaaaa tatagaaaaa gcaaagatag ctaaacttga
     1921 agctgatata agtgcaataa aaagtgcatc tcttagttac tatgctgatg aatccaagta
     1981 tactgatgga ggaatgatat catgggtaaa gaaagatgga aaaataataa taaatggggg
     2041 ttttaaagat gacccattag cagataaaat agaaaattta gggatgcctt ataatggttc
     2101 atatctgtta atgtcatctc ctggtcatga aaaatatcta gaattaagca tacttccaga
     2161 aggagaaata agcaaaagtg gtctagataa attaaaaaat gattatggaa atttaataga
     2221 cataacgaac gatcaaaata aaataaatat tgtaataaaa cttttaaata ataaatcgaa
     2281 tacttaaata caataaattt gatttaataa ttactgatga aataaacaat cttgtttgga
     2341 gaaatgaaaa aagcactccc caagaataga atgcttagtt ataactacag aagtgtattg
     2401 gcatacactt ctatttttta ttatatcaca taatttatgt tgctaaaaat acctatttaa
     2461 gttgttttta aattgtgttg agtaatattc ttgatagttt atacattaat gaatttcaaa
     2521 aaaataagca ctctttataa taaaaagtac tttagtgtat gttaatgtcc tatctaataa
     2581 aattgtaaca tgtcttatgc tttagtatga taattttcat tctctttatt gttgcaactt
     2641 atactatagt tttgctaatt tatctgcaaa cacaacttct ttattgcatg tgtatcaacc
     2701 aaaaacatca gaatacttac ttaatacatc tgcaaaatcg tatctttcat ctatagtatt
     2761 cttatttgac aatataacaa aaaatgaatc gagatatgcc ttttttataa ttagatatat
     2821 tttataaatt ctagcatatc atttgttatt ttctgatatg ctattgatgt tttaaatctt
     2881 ctatttattt tattattttt tacttttcca attgtacctt tataggagtt atatttatgt
     2941 gatttatgaa aaaatgctat gcatttaagt tctaattttt tgataataca tctaactttc
     3001 ttttgattaa taatgatacc actattttta atgtggcttc cctgaggcac acatcttttt
     3061 taaaaactca agctcatctt ttaaaaattt attttcatat tctaattctt gttctcttgt
     3121 taatttattt tttctttagt gtttttgttt ttattcatta tggtcttcct ttcattttga
     3181 aaaaggcatc aacaccacta tgtaaaaatt tttgttttca tgttgctata actgtgctat
     3241 tgtttattcc aaaatactta gcgatttatt gtacactata cttagttatc atcatatagt
     3301 ttataacatc taacttgaac catatagtat agaaaacttt tttattttta gtgcaccctc
     3361 tcctaatata ttaacccatc tttcaacttg agaatggtca taaactccat attgttttac
     3421 tattaaaata tctcttcctt ctctattcaa ataaaattta gctactttta atttgaaatt
     3481 aaaatcatat ttagtcatac ataaacatct caagcgttag atttttactc taacaattat
     3541 ggtgcagtac aaatattgta taatactgat tttctattga caaaagaata taaaagagat
     3601 atatttgtat tataaagata caaatatatc tcttttaaaa ttactaagga ggataaaaaa
     3661 tgattcaaaa aaaaattttt atgggttttt gtggtttcct tggattttta agtcttagat
     3721 atttttcatc tggcaatgtt actgatctta catatattgg attttttgct tttttctcaa
     3781 actttattat agcaaaaata aatggtgata aagcagatga aaggtatgta caagatgaaa
     3841 aagcagctat ggcatttaca ggacagcttg ctattataga attattcatt ttatggtgta
     3901 ttactatagt gtctaggaat gtagaattaa tgtgtgtttt actatcaatt acatatgcaa
     3961 tcactttaaa tgtttatgct ataaaacttt atattttaga ggaaaaataa tatgcccaaa
     4021 ttcatttgta acctaaaaaa atatagacaa ttaaaagaat taactcaaga acaattagca
     4081 gaaaaagtag gagttagaag agaaaccatt atgcgtttag aagcaggaaa gtataatcct
     4141 tctttgaaat tagcaataga tatatcaaaa atagtagata cacctattga tgaattgttt
     4201 atttttgatt agtttttgca ttattaaaaa tgtgttttaa atacaaactt aaattcaatc
     4261 tttaagtcac tcctga
//
LOCUS       DAMJYN010000175         4270 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.181, whole genome shotgun sequence.
ACCESSION   DAMJYN010000175 DAMJYN010000000
VERSION     DAMJYN010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4270)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4270)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4270
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.181"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            254..592
                     /locus_tag="PC466_003631"
     CDS             254..592
                     /locus_tag="PC466_003631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2770979.1"
                     /translation="MANIGKIIGDRIKVYRTKLGYSQEFLAEKAGLHPTYIGQIERAE
                     TNTSINIIMKIATALDIPLELLFANIITTEGVDNSVPLECYEMINKLTEKEQIAMLEL
                     IKCIIKYKEI"
     gene            614..931
                     /locus_tag="PC466_003632"
     CDS             614..931
                     /locus_tag="PC466_003632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2770980.1"
                     /translation="MNYIGKRLKEERKKANLTSKEFANMVGVSPWYITQIESGKKNPS
                     LKTFIKFVNILNISADVLIKDITSTGKTYLENDINEELKDLNSRELNLISQIIDIIKK
                     NKI"
     gene            1081..1758
                     /locus_tag="PC466_003633"
     CDS             1081..1758
                     /locus_tag="PC466_003633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770981.1"
                     /translation="MIVIEGSDKFKIAKEYIDVEYTLFSKVTFRYEKLKFKDNAELEK
                     IKMFKYKNGYIPNKLNLSFGYGFSSYKKQIIRETVDTLRLTEIFSSENIEDIKFIKDG
                     TKKLEISIEKVVKFKRRKKRNYVCCYCPDMYRDIKLDKESINKIYNRKIKIEREVNIF
                     EDEDVIINKKVLKFPKSWTKNMQKYWLSENKYPIHSTVIDDDRYKCCNVQYTKNRVII
                     LYYIYNH"
     gene            complement(2086..2853)
                     /locus_tag="PC466_003634"
     CDS             complement(2086..2853)
                     /locus_tag="PC466_003634"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HDF2770982.1"
                     /translation="MKRKVQVKNITIGEGRPKICVPIIGKNKKDIIKEAKELKDACLD
                     IIEWRVDFFENVENIKEVKEVLYELRSYIHDIPLLFTFRSVVEGGEKLISRDYYTTLN
                     KEISNTGLVDLIDVELFMGDEVIDEVVNFAHKKEVKVIISNHDFNKTPKKEEIVSRLC
                     RMQELGADLPKVAVMPQNERDVLVLLEATNEMFKIYADRPIITMSMSGMGVISRLCGE
                     IFGSALTFGAAKSVSAPGQISFKELNSVLNLLHKSIN"
     gene            3659..>4270
                     /locus_tag="PC466_003635"
     CDS             3659..>4270
                     /locus_tag="PC466_003635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CatB-related O-acetyltransferase"
                     /protein_id="HDF2770983.1"
                     /translation="MTIPNSNKVYPRSNDYQTVYLKNVITRENIEVGDYTIYNDFYND
                     PRDFEKNNVLYHYPINNDKLIIGKFCSIACNAKFLMTSGNHSMKSKSTYTFPIFYEEW
                     KLDINHITDAWDNKGNIIIGNDVWIGYDSIIMSGVNIGDGAIIGTRAVVTNDVSPYSI
                     VGGVPAKIIKKRFNNDTISKLLEIKWWDWPYKKIQSNIKHIQSG"
BASE COUNT         1727 a          533 c          530 g         1480 t
ORIGIN      
        1 aaaaaatgct ataattaaca tattattaat tcgttttatt attgtagtat ggctatgaaa
       61 ttatgaaaat atttctctaa ttaaaaatat gatttatcca tatttgttta ttgtagatac
      121 agactataca aaaataaata gcacttattt cagtataaaa acatatatag tctatattta
      181 gactaaaaaa gtataaatag tctatataaa acaacttaaa ctatgaatat aatctaaagt
      241 ggagggataa taattggcaa atataggaaa aataatagga gatagaataa aagtctatag
      301 aacaaaattg ggatatagtc aagagtttct agcagaaaag gcaggtttac atccaacata
      361 tattggtcag attgaaagag ctgagacaaa tacatctatc aatattataa tgaaaattgc
      421 tactgcttta gacataccac ttgaattgtt atttgcaaat attattacaa cagaaggcgt
      481 tgataactct gtacctttag aatgttatga aatgattaat aaattaactg aaaaagaaca
      541 aattgcaatg ctagagttaa taaagtgcat cattaaatac aaagaaatat aagtgaggga
      601 aatagtaaca ataatgaatt atataggtaa aagacttaaa gaagaacgaa aaaaagcaaa
      661 tttaacttca aaagaatttg caaatatggt tggagtatcg ccttggtata taactcaaat
      721 cgaaagtggt aaaaagaatc caagtcttaa aacattcata aaatttgtaa atatattaaa
      781 tatttctgca gatgttctta taaaagatat tacttccact ggaaaaacat atttagaaaa
      841 tgatataaat gaagagttaa aagacttaaa ttcaagagaa ctaaatctga tatcacagat
      901 tatagacatc ataaaaaaga ataaaatata attctttata ttttatataa aaaaaaaggt
      961 tatttgaaat aaataacctt tttttgtctt tttgtgttaa cattgtctta tagtgctaat
     1021 gagtactatt agaccatgtt ctatggcctt attttaatat aaaacgattg gagataggct
     1081 atgattgtga ttgaaggtag tgataaattt aagattgcaa aagaatatat tgatgtagaa
     1141 tatactcttt ttagcaaagt aacttttagg tatgaaaagt tgaaatttaa agataatgct
     1201 gaattggaaa aaattaagat gtttaaatat aaaaatggct acatccctaa taaattaaac
     1261 ctttcttttg gatatggatt ctcttcttat aaaaagcaaa taattagaga aactgtagat
     1321 actttaagat tgacagaaat tttttcaagc gagaacatag aagatattaa atttataaaa
     1381 gatggtacaa aaaaattaga aattagcata gagaaagttg tgaaatttaa acgtcgaaaa
     1441 aaaagaaatt atgtttgttg ctattgccct gatatgtata gagatataaa actcgacaaa
     1501 gaatctatca ataagatata caacagaaaa ataaaaatag aaagagaagt taatattttt
     1561 gaagatgagg atgttataat aaacaagaaa gtattgaagt ttccaaagtc ttggacaaag
     1621 aatatgcaaa aatattggtt aagtgaaaat aagtatccca tacattctac tgtaattgat
     1681 gatgatagat ataaatgttg taatgtacaa tatacaaaaa atagagtgat aatattatat
     1741 tacatatata accattaata tacataatta caaaaaaata atgacaaata tacataatac
     1801 aaatatatct tctactttag ataaaacagt tattatgaaa acttactatc tataaataat
     1861 agaaatgcta gtataccatc tataatctaa tgtctagtag gttttaatgg catattttaa
     1921 atatgccata gttgatttat aagattttct atatcacttt caaaatacac actaaatagt
     1981 tgcttttcag atataattgc ccaatttaaa ttttactatc tgaaaagttt tttatattta
     2041 atttatatct tcaaaaatac cgtctaatat ttctatataa ttaatttaat taatactctt
     2101 atgtaataga ttaagtactg aatttaactc tttaaatgat atttgccctg gtgctgaaac
     2161 actttttgca gctccaaaag tcaatgcaga accaaatatt tcaccacaca atctacttat
     2221 aacacccatt cctgacattg acattgttat tattggtcta tctgcataaa ttttaaacat
     2281 ttcatttgta gcttcaagta gcactaacac atctctttca ttttgcggca taacagctac
     2341 tttgggtaaa tctgcgccca attcctgcat tctacataaa cgagatacaa tctcttcttt
     2401 ttttggagtt ttattaaaat catgattaga tataattact ttcacttctt ttttatgagc
     2461 aaaattaact acttcatcta tgacctcatc tcccataaat aactctacat ctattaaatc
     2521 tactaaacct gtattagaaa tttctttatt caaagtagta taataatctc ttgatattaa
     2581 tttttctccc ccttctacta cacttctaaa tgtgaataat aaagggatat catgtatata
     2641 acttcttaat tcatagagaa cttccttaac ttctttaata ttttctacat tctcaaaaaa
     2701 atcaactcgc cactctataa tatccaaaca tgcatctttt aactctttag cctcttttat
     2761 aatatctttt ttatttttcc caataattgg tacacaaatt ttaggtctac cttctccaat
     2821 agtaatattt tttacttgaa cttttctttt catattctcc tccataatca gaaattctat
     2881 aggactttaa attctatttt ctgcataatt taattataca ttaaaaatac tatacattat
     2941 aaaaatacta atttaaaaat aatttttatt ctaattctta aaacaatccc acatatttta
     3001 gaaaaggtac tctataatat acaaacactt cttttttacc taaatttatt ttaacattct
     3061 ataattttca caatattctt taaattttac tcatataaac aatattattc tggatgctaa
     3121 tagaattaat ctataaatca tagtataatt atgcagaaat aactcgaatt tcactactta
     3181 taaagagatt gaatattaat gaatctaaat catttgcatt acttcagagt tttgactaaa
     3241 gttgaacacc atacaaaagt agctactcaa ttgtttatac cccaaccaag cttaagtaat
     3301 gttatataga ttcttgaaaa agaatttggt atctttttat ttgaaaaaca aggtagaaat
     3361 gtttccctca ctaaatacgg aagttttttt ctaacctatg ttgataaagc attaggttaa
     3421 ttagaaaaag tttacatata aaatatatta aattgttgca agttttattg ttttgatata
     3481 caatcaacta aacatataat ctttataaaa tactatacag ttaaaagtct gttttaaaaa
     3541 aaaatgtata aattataaat caaaatatag atactatcaa ggagtgattc tgtgaagaga
     3601 tgtattgtag tagtggaata gtcaaaaaca taatatatat taaaggagag atttaaatat
     3661 gactattcca aattcaaata aggtatatcc aagaagtaat gattatcaaa ctgtatatct
     3721 taaaaatgta ataacaaggg aaaatataga agttggagat tacacaatat ataatgactt
     3781 ttataatgac ccaagagatt ttgagaaaaa caatgtatta tatcattacc ctataaacaa
     3841 tgataaatta ataattggta agttttgctc aatagcatgt aatgcaaaat ttctaatgac
     3901 tagtggaaat cactcaatga aatcaaaatc cacatatact tttcccatct tttatgaaga
     3961 atggaaactc gatatcaacc atataacgga cgcttgggac aataagggta acattataat
     4021 tggaaatgat gtgtggatag gttatgattc tataattatg tcaggtgtaa atattggtga
     4081 tggtgcaatt attggaacaa gagcagtagt tactaatgac gtctcaccgt attctattgt
     4141 tggaggagta cctgcaaaaa ttataaaaaa gagatttaat aatgatacaa tttcaaaatt
     4201 attagaaatt aaatggtggg attggccata taaaaaaatt caatcaaaca ttaagcatat
     4261 tcaatcagga
//
LOCUS       DAMJYN010000176         4067 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.182, whole genome shotgun sequence.
ACCESSION   DAMJYN010000176 DAMJYN010000000
VERSION     DAMJYN010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4067)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4067)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4067
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.182"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(221..604)
                     /locus_tag="PC466_003636"
                     /pseudo
     CDS             complement(221..604)
                     /locus_tag="PC466_003636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431032.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
     regulatory      831..928
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            983..1159
                     /locus_tag="PC466_003637"
     CDS             983..1159
                     /locus_tag="PC466_003637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770984.1"
                     /translation="MFGNKMDKCTHVLTAYISGSYDYCNFLDTQLDDFILEYGESVVE
                     SCLHQVMVLVSKYN"
     gene            1385..1585
                     /locus_tag="PC466_003638"
     CDS             1385..1585
                     /locus_tag="PC466_003638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000809131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HDF2770985.1"
                     /translation="MNNGIVKWFNNEKGFGFISMEGRDDVFAHFSAIQTSGFKSLEEG
                     QQVSFDIVKGARGPQAENITIL"
     gene            complement(1749..2048)
                     /locus_tag="PC466_003639"
     CDS             complement(1749..2048)
                     /locus_tag="PC466_003639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770986.1"
                     /translation="MGFYINYVVCKVKILFSSFSKIILFYINYVVCKLFITLKAILLK
                     TQIIVTTHSPHILQIDSKEEMIVLDMAESGNVYKKELELGEYGVLGWTNEGLYLH"
     gene            2270..2452
                     /locus_tag="PC466_003640"
     CDS             2270..2452
                     /locus_tag="PC466_003640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HDF2770987.1"
                     /translation="MFKFYNNATLMFLSGTNIKTISERLGHADIKITMNSYSQFLEEM
                     DREAFENLSKILFIVF"
     gene            2523..3368
                     /locus_tag="PC466_003641"
     CDS             2523..3368
                     /locus_tag="PC466_003641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770988.1"
                     /translation="MNIIKSITLLLTLLIVILMTGCSPRESASEVAKKYIDKMNSGDY
                     ETAYSLLSKDSKKKISIENLEEFQNILVSTKRIISYKIGKEKIIKKYKHDGKEYKNVV
                     KLEETFNIKNLLYKKDDSLKVNRYFVVENNKYKLLLYESFKKEFGINSMDLAQLKLND
                     FGLKYFKEVDLILKKAIAINPTDSKLYYAQACNYMNFDGFPGYSDTTYNALDSINNSL
                     KYLDKNDSDYKKNASNIYNLKGVILMFHKRFDEAQQYLNKALYFNKDNEDPKYNLNTI
                     KKHLN"
     gene            complement(3592..3756)
                     /locus_tag="PC466_003642"
     CDS             complement(3592..3756)
                     /locus_tag="PC466_003642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770989.1"
                     /translation="MFGKPKESVRFLDFNDVAEKFGEKKAVAIFDAIAGKKSKEHIIK
                     DIEKLVKNEV"
BASE COUNT         1540 a          506 c          473 g         1548 t
ORIGIN      
        1 ataaaagaca gtaatttatc tatagtgtta cttatatttt atatatatgg ctatttttca
       61 acattttaca atatatataa catttatttt tttaactttt gtcagtaaaa tgtcagcaag
      121 acactttatc cacaattttt atataagttt tccacaactt atccccagta ttatccacat
      181 aaaaaaggta gctcttatat tattagctac cttttattta ttaatcttca tatttccagc
      241 tttttatcca acttcctatt tctattattt tttcttcagt tatttcttct ccatcatgta
      301 attttgaaat taattctgat aaaggattgt tatgtaaacc tctaaaaact ctttttccct
      361 ctattttgag atattctctc tcttttatta atactgtata gtgtacatgc ctcccaattc
      421 tctatgatat taaaaaacct tttttggtta atctagctaa aagtataatt gtagttgtat
      481 gcttccaacc atatgttttt tctatttcat ctgcaacatc ttttgatatt acagttttat
      541 aaccagtatt ccatatgcat ttcataattt ttaattctgt atctggtaat tttttattta
      601 gcataatata ttccttcttt caatttatgt cacttcttca aatttatcta gcttaaatta
      661 taataggagt tttttagaac aaaaactata gttaattttt accaggtact ctacgtgttt
      721 agtctgtttt ttaagtgtaa aataatgttc atatctataa atttatttaa ctttcaaaca
      781 atcctgttga ataataacta attctattgt attattttag ttgtagaata aaactaaatc
      841 ggcaaaacta gagaaattta gtgacgcaaa gctataggga ctaagactta tataaatatc
      901 ttatgagtta tgtcagccag ttgccaaaga gatagtgttc tttttgtttt tatgaaagtt
      961 ttttaggggg ataataattt atatgtttgg aaataaaatg gataaatgta cacatgtatt
     1021 gactgcttat attagcggtt cgtatgatta ttgtaatttt ttagatacac aattagatga
     1081 ttttatatta gagtacggag aaagtgtagt agagtcttgt ttgcaccaag tgatggtatt
     1141 ggtaagtaag tataattaga tagacattga tttctagaga acccttttta gttttatcta
     1201 catttatatt aatatatagc aatgtaaaac gcttaaatat atttttaata ttaagaataa
     1261 ctaaaatgtt gactaaaaaa tataattaag tagacatttc tattaatcta tgatacaata
     1321 gtatttgtgg taatacacaa ttaaatcaag tatatcttga tataggttaa taggagtatt
     1381 tttaatgaat aatggaatag tgaaatggtt taataatgaa aaaggattcg gttttatatc
     1441 aatggaaggt agagatgatg tgtttgctca tttctcagct atacaaactt caggatttaa
     1501 atcattagaa gaaggtcaac aagtaagctt tgatatagtt aaaggtgcta gaggtcctca
     1561 agcagaaaat ataactatat tataatatat agatttttcg ggaaagactc tttttagagt
     1621 ctttttttat tgttagtata tgtaagataa tcattggtga agtaaataag gtatattgag
     1681 taatgttctt gatagtttat atgctaatga atttcaaaaa aataagcact cctataaaaa
     1741 gagtgctctt aatgtaaata taagccttca ttggtccagc ctaatacccc gtattctcca
     1801 agttctaact cttttttata tacattacca ctttcagcca tatctaacac aatcatttct
     1861 tctttagaat caatttgtaa aatatgagga ctgtgtgttg tgacaattat ttgtgttttt
     1921 aggagaattg cttttaatgt aataaaaagt ttacatacaa catagttaat ataaaacaaa
     1981 attatttttg agaatgagct aaataaaatc ttaactttac ataccacata gttgatataa
     2041 aaccccaaaa taaacttagc atctccaatg tttacacata tacaatgctc ttaaaattgc
     2101 agtgaacatg caatagtgca attgataata cttatcatat attctcaata ccttatattt
     2161 caactgctaa acctcaattt gtcacaaata tcgctcactg caaaatttct atatttttat
     2221 tatatcatag catataatta atattttcaa ttaattttta catttaatta tgtttaaatt
     2281 ctataataat gcaactttaa tgtttctttc tggaactaat ataaaaacta tttcagaaag
     2341 attaggtcat gcagatataa aaataactat gaatagctac tctcagtttt tagaagagat
     2401 ggacagagaa gcatttgaaa atttgagcaa aatactattt attgtatttt aaagaagatg
     2461 acttattcaa tatttgatgc tagaatataa ttaataaaaa tttaattata ggtgattgta
     2521 ttatgaacat tattaaaagc ataactttac tcttaacatt attaattgtg atattaatga
     2581 caggatgttc cccaagagaa agtgctagtg aagttgcaaa aaaatatatt gataagatga
     2641 actctggtga ctatgaaaca gcatatagtt tattaagtaa agatagtaaa aaaaaaatta
     2701 gtatagaaaa tcttgaagaa tttcaaaata ttttagttag tacaaaaaga ataattagtt
     2761 ataaaatagg taaagaaaaa atcataaaaa aatataaaca tgatggaaaa gaatataaaa
     2821 atgttgttaa attagaagaa acttttaata taaaaaacct tctttataaa aaagatgatt
     2881 ctctaaaagt aaatagatat tttgtagttg aaaataacaa atacaagcta ttattgtatg
     2941 aaagtttcaa aaaagaattt ggtattaata gtatggacct tgctcaactt aagcttaatg
     3001 attttggact aaaatacttt aaagaagttg accttatact aaaaaaagct attgctatta
     3061 atcctactga ttcaaagctt tattatgccc aagcatgtaa ttatatgaat tttgatggat
     3121 ttcctggtta ttcagataca acatataatg ctttagattc aattaataat tctttaaagt
     3181 atttagataa aaatgattct gactacaaaa aaaatgcaag taatatatat aacttaaaag
     3241 gagttattct tatgtttcac aaaagatttg atgaagcaca acaatattta aataaagcct
     3301 tatactttaa caaagataat gaagacccaa aatataatct aaatacaata aaaaaacatc
     3361 taaactagat atttaatttt tgaatttata aaatattttt ttatgtataa ttcagcactg
     3421 aatcataatc tctactaaac taattacaag tttaaattat aaagacttat ttctatataa
     3481 atattactct ataacaataa gtttcttatt taaattttaa aatattatct aaaaatcata
     3541 aaaaagaagg tataaagagc taccctcaag ctcaatatac cttataaata tctaaacttc
     3601 attttttact aatttttcta tatctttgat aatatgttct ttagattttt ttccagctat
     3661 ggcatcaaaa attgcaacag cctttttctc tccaaacttt tctgctacat cattaaagtc
     3721 taaaaatcta acactttctt ttggtttacc aaacatataa cacctctcat acatttttat
     3781 atatttatta taacttctat agacttattt ttcaccaata aacgttagac aaattagtcc
     3841 ctttattttt ttaaactagc tttaccttca aaattcttaa caaaaacagt ttattctact
     3901 ctataaataa aaatagacaa tttaatttgt aggaaactga taatagaata cagtaaataa
     3961 aactttgttt aatctatctg aaaaagttat ctattaaaac tgctatgaat ttataaagaa
     4021 tattctagtt cataaaaata caaatatgta aatataatca ccttaat
//
LOCUS       DAMJYN010000177         4015 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.183, whole genome shotgun sequence.
ACCESSION   DAMJYN010000177 DAMJYN010000000
VERSION     DAMJYN010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4015)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4015)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4015
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.183"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            208..1713
                     /locus_tag="PC466_003643"
     CDS             208..1713
                     /locus_tag="PC466_003643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HDF2770990.1"
                     /translation="MKIQNTEWGYIEWKHTYDENNPKQAMNIYIAVTMPGKKHFNHVH
                     YGQEQMIYILEGEGLYIINGVWKPFYQGMIFYIESGSTHETINTGDREIKELIVSNNV
                     DDVGESEVIDINPNNYLKKTLINYSESTLNLYAAVESIRGQFIDPFKIPLIIYDDSWN
                     IVLKNPYFPLFCFEKCNPMKFPQNCDCMNQKSSNQFVCEYGITIYNIPILYKSNSIGV
                     IRGGYVLLSDLNLDTEHNNLYDIPEGAARSIKRLLKQISKNIINFCSFNDIRKDLQEK
                     EKTIARTYHYGEQLEMNLKVAQDMVTNLRINHHFLFNTLNSMASIALDDGSYDLYSAI
                     IDLSRMFRYTMRSDLRFVELESEILYIKNYLNLQKLRYGDALKVKYLIPEKLYNLSVP
                     FNFIQPIVENAFTHGFRDIDTEKRIEIIARLDSQYAIIEIHNNGTILDGNNIDKIKAG
                     IRSNNGHGLSLIYTKFTSAYGNNFDMDIKSSDNEGTYIMIKIPIENYKEYV"
     gene            1827..2525
                     /locus_tag="PC466_003644"
     CDS             1827..2525
                     /locus_tag="PC466_003644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HDF2770991.1"
                     /translation="MRRALIIDDEEAVLKIITHFIEMKDMPIKIVGKATSGDEAVDKI
                     IGLEPDIVFIDIQMPIYNGLEVIEKTSHLSKKINFVVITAFNYFEYAQKALRLNVKDI
                     LLKPLDMKEFTKSVEKIIGYQYTNNDLLNEILEYINLNYSNDLKLNDCARLFLTNPSN
                     ISRIFKSNLNTTFISYLNHIRIEKSIELLENTTKSINEIAEIVGYNSLNNFYKNFKIE
                     KGMTPKVYKLNTKN"
     gene            2810..3898
                     /locus_tag="PC466_003645"
     CDS             2810..3898
                     /locus_tag="PC466_003645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770992.1"
                     /translation="MSDKVNMKNIICIAGAYLATAIGSGFATGQEILQFFASQGYMGL
                     IGALISMVLFSFLGAEVITRGRELKLKEPTRIYTFYCGKILGKFYEWFSPIFLFGILI
                     VMISGAGSTLTEYYGINPYLGRVLMAVATLITVSMGLEKLVSILGRIGPVIAVFTIAV
                     GLISLFKHFDGLSMVGEAMKNIEVTKASESPIVSGVIYNTLNIIVMIVFLTGMGASIE
                     SKKDAFWGGLLGGIVFMTAGIVMYLAMISDIGNLYMKEIPSLYLADNISPIVGVCFSV
                     ALILGIYTTAVPLLWSVTNRIVEDEHPKFKLVTTVIAILACIGGFLPFGKLVNILYPY
                     TGYMGLLILVCMVYKAITCRKKSTQSQE"
BASE COUNT         1596 a          394 c          643 g         1382 t
ORIGIN      
        1 acaataatat agaagtaata aaaaaatagt taatataaaa gtgatacaat aataatagaa
       61 gtaataaaaa aaaataatta atataaaaat gtgtacaaac taatgaatat tgatatagta
      121 agctatcata tgaaagagta tgtacacatt ttttttacta atttttcaca atatgaacat
      181 aaataattta caggaaagga atcttttatg aaaattcaaa atactgagtg gggatatatt
      241 gaatggaaac atacttatga tgaaaataat ccaaaacaag ctatgaatat atacattgca
      301 gtaactatgc ctggtaagaa acattttaat catgttcatt atggtcaaga gcagatgata
      361 tatattttag agggagaggg tttgtatatt ataaatggag tttggaagcc attttatcaa
      421 ggtatgattt tttatataga atctggtagc acacatgaaa ctataaatac aggcgataga
      481 gaaataaaag aacttattgt ttcaaataat gtagatgatg taggagagag tgaagttata
      541 gatattaatc ctaataatta tttaaagaag accttgataa attatagtga aagtacatta
      601 aatttgtatg cagcagtaga atcaattcgt ggtcaattta tagacccgtt taaaattcca
      661 ttaattatat atgatgattc atggaatata gttttaaaaa acccttattt tccacttttt
      721 tgttttgaaa aatgtaatcc tatgaaattt cctcaaaatt gtgattgtat gaatcaaaaa
      781 agtagcaatc aatttgtatg tgaatatggg ataactatat ataatatacc aatactgtac
      841 aaaagcaata gcataggtgt tataagagga gggtatgtac tattatctga tttaaattta
      901 gatacagagc ataataattt atatgatatt ccagagggag ctgctagaag tataaaacgc
      961 ctcttgaaac aaatatctaa aaatataata aatttttgct cttttaatga tataagaaag
     1021 gatttacaag aaaaagagaa gactatagca agaacatatc attatggaga gcaacttgaa
     1081 atgaatttaa aagtagctca agatatggtt actaatttaa gaataaatca tcacttttta
     1141 tttaatacat taaattcaat ggcaagcata gcactagatg atggtagtta tgatttgtat
     1201 agtgcaataa tagatttatc aagaatgttt agatatacaa tgaggtctga tttaagattt
     1261 gtagaattag aatctgaaat attatacatt aaaaattatt tgaatttaca gaaattacgt
     1321 tatggagatg cacttaaagt aaaatatctt attccagaga agttatataa cctttctgtg
     1381 ccttttaact ttattcaacc tatcgtagag aatgcattta cacatggatt tagagatatt
     1441 gacacagaaa agcgaattga aataattgca agattagatt ctcagtatgc tattatagag
     1501 attcataata atggaactat cttagatgga aataatatag acaaaataaa ggcaggtatt
     1561 cgtagtaata atggtcatgg tttgtcttta atatatacaa aattcacatc tgcttatgga
     1621 aataattttg atatggatat aaagtcgagt gataatgaag gaacttacat aatgattaaa
     1681 attcctattg aaaattataa ggagtatgta tagaacttgt gaaaaattaa taagttttat
     1741 aaatgttaag aaatatatta gatgttttta tgttgtttta tatatcttac ttttttatat
     1801 tattaagcta aaagggaggt attctcatga gaagagcact aataatagat gatgaagaag
     1861 ctgttctaaa aataataaca cattttatag aaatgaaaga tatgccaata aaaattgttg
     1921 gtaaagcaac atctggtgat gaagcagtag ataaaatcat tggtttagag ccagacatag
     1981 tttttataga tattcaaatg ccaatataca atgggttaga agtaatagaa aaaacatctc
     2041 atttatctaa aaaaataaac tttgtagtaa taactgcatt taactatttt gaatatgctc
     2101 aaaaagcttt gagattaaat gtaaaagata tactccttaa accattggat atgaaagaat
     2161 ttactaagtc tgtagaaaaa attattggat atcaatatac caataatgat ttattaaatg
     2221 agatactgga atatataaat ctaaactata gcaatgactt aaagttaaat gattgtgcta
     2281 gattattttt aaccaatcca tctaatatat ctaggatttt taaaagtaat ttaaatacaa
     2341 cttttatatc atatctaaat catataagaa tagaaaaatc tattgaatta cttgaaaata
     2401 ctacaaaaag tataaatgag attgcagaaa tagttggata taatagccta aataactttt
     2461 ataaaaactt taagatagaa aaaggaatga ctccaaaagt ttataaactg aacactaaaa
     2521 attgaaattg ataaataaaa agtcaatata gataattgtt tgagtgtgtc tgaataagta
     2581 tactttaatt atgataaaaa ttaaagcgct ttaaacatat ttaataatat taaaccttat
     2641 aaaagctgta cctatttata taaaaaaata tatataaata aaaagaaaaa gatatacaaa
     2701 ataaaaaaag tgaattaaat actgtttcaa aaagacagaa ttttcattta attcactgag
     2761 agtttatatt tcttaaagga aggtaacttt ataatggagg taatttaata tgtcagacaa
     2821 agtgaatatg aaaaatatta tctgtattgc aggcgcttat ctagcaacag caattggttc
     2881 tgggtttgct actggtcaag aaattctaca attttttgcc tcacaagggt atatgggttt
     2941 aattggagca ttaatatcaa tggtattgtt ttcatttctt ggtgctgaag ttataactag
     3001 aggtagagaa ttaaaactta aagaaccaac aagaatttac actttttatt gtgggaagat
     3061 tttaggaaaa ttttacgaat ggtttagtcc aatattttta tttgggattc ttatagtaat
     3121 gatttcaggt gcaggctcaa ctttaactga atactatggt ataaatcctt acttaggaag
     3181 agtattgatg gctgttgcta ctttaattac agtgtctatg ggtttagaaa aattagtaag
     3241 catacttgga cgtattggac cagtgatagc agtatttaca attgctgttg gattaataag
     3301 cttgtttaag cattttgatg gtttatctat ggttggagaa gctatgaaaa atattgaagt
     3361 tacaaaagca tcagaaagtc caatcgtttc tggtgtaata tataatacat taaatattat
     3421 tgtaatgatt gtttttttaa caggaatggg agcttctatt gaaagtaaaa aggatgcttt
     3481 ttggggaggt ttattaggtg gaatagtgtt tatgactgct ggtatagtta tgtatttggc
     3541 tatgatttca gatataggaa atttgtatat gaaagaaata ccatcacttt atttagcaga
     3601 taatatatct cctattgtag gtgtatgttt ttcagttgca ttaatattag gtatctatac
     3661 aacagctgtt ccacttttat ggtctgtaac caatagaatt gttgaagatg aacatcctaa
     3721 atttaaattg gtaacaacag taatagctat tttggcttgt ataggtggtt ttttaccgtt
     3781 tggtaaatta gtaaacattt tatatccata tacaggttat atggggcttt taattttagt
     3841 ctgtatggtg tataaagcaa ttacatgtag aaaaaaatca acacaaagtc aggaatagag
     3901 tcacctatta atagttttta tttaaagaaa ttttttatat aatccgaatt taaaaagtca
     3961 aaatagttaa ataaattgca aaacatgata atatatttaa ttaaaataat atagt
//
LOCUS       DAMJYN010000178         3939 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.184, whole genome shotgun sequence.
ACCESSION   DAMJYN010000178 DAMJYN010000000
VERSION     DAMJYN010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3939)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3939)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3939
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.184"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            <1..239
                     /locus_tag="PC466_003646"
     CDS             <1..239
                     /locus_tag="PC466_003646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005209661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2770993.1"
                     /translation="VEESRPNILDAIRNKQVDIVINTPTKGNDSTRDGFKIRRTAIEF
                     STEIMTSLDTLKALVEVKKKHLNKDELKVYNIAE"
     gene            497..1546
                     /gene="carA"
                     /locus_tag="PC466_003647"
     CDS             497..1546
                     /gene="carA"
                     /locus_tag="PC466_003647"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002845470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HDF2770994.1"
                     /translation="MKARLILEDGTVFIGKAFGYLEESVGEVVFNTSMIGYGEVLTDP
                     SYYGQIVTMTYPLVGNYGINLSSAESEKVQVKGFIVREKSDSPSNFRCEIDIDQYLKQ
                     NKVIGLEGIDTRALTKILRNNGTMKGIITLEDSKLEDVKHKLDKFSNTEAVRTVTRKE
                     VEHIKGNGPKVAVMDFGVKRNILRSFIARGCDITIFPATTSPEDVLSINPDLIFLSNG
                     PGDPEDLEDVIENIKALIGKKPIVGICLGHQLLALALGGKTAKLKFGHRGGNHPVKDL
                     EEGKVFITSQNHGYYVSEVPEQMKVTHINLNDNTVEGMRHEKLDVYSVQYHPEACPGP
                     KDNDYIFDKFLELVK"
     gene            1739..>3939
                     /gene="carB"
                     /locus_tag="PC466_003648"
     CDS             1739..>3939
                     /gene="carB"
                     /locus_tag="PC466_003648"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) large subunit"
                     /protein_id="HDF2770995.1"
                     /translation="MPKLDSIKKTLVLGSGPIIIGQAAEFDYSGTQACQALKEEGIEV
                     VLVNSNPATIMTDKEIADKIYIEPLTIEFIEKIIEKERPDSLLAGMGGQTGLNLAVEL
                     HDAGILDKYNVKVIGTSIESIKKGEDRDLFREVMKEINQPVIVSDIVTNLEAGLEFAN
                     KIGYPVVVRPAYTLGGTGGGIADTEEELREILSHGLQLSPVGQVLLEKSIKGWKEIEY
                     EVMRDGNGNCITVCNMENVDPVGVHTGDSIVVAPSQTLSDEEYQLLRKASIDIINAIE
                     VQGGCNVQIALNPHSLEYAIIEINPRVSRSSALASKATGYPIAKVAAKIALGYTLDEI
                     ENAVTKKTYACFEPTLDYVVVKIPKWPFDKFRHANRKLGTKMMATGEIMSIGSNFEAA
                     ILKGIRSLETGKYSLVHAPSEGRTLEELKARVVVPDDERLFDLAEMIRRGYKVEMISE
                     ITGVDKWFINKFKWIVEQEEKLKVLKIEDLDKEYLHELKKKGFSDKGISDLMKISPEK
                     LYELRSLYNIQPVYKMVDTCGGEFEALSPYYYSTYEQYDEVVVSDKRKVVVLGSGPIR
                     IGQGIEFDYCSVHCVKSLRKMGIETIIVNNNPETVSTDFDTSDKLYFEPLTEEEVLNI
                     IEKEKPEGVILQFGGQTAIKLAKFLHEKNIPILGTDFRDIDAAEDREKFDDLLERLDI
                     NRPKGKGVWTTNEGVEIAKELGYPVLVRPSYVLGGQGMEITYNEEKLIQYL"
BASE COUNT         1630 a          400 c          777 g         1132 t
ORIGIN      
        1 gagtagaaga atctagacca aacatattag atgctataag aaataaacaa gttgatatag
       61 taataaatac accaactaaa ggaaatgact ctacaagaga tggatttaag ataagaagaa
      121 cagctattga attttctact gaaataatga catctttgga tacactaaaa gctttagtag
      181 aagttaagaa gaaacattta aataaagatg agttaaaagt ttacaatata gctgaataga
      241 aattaagttg attgtatagt ttaagaattt aattattaaa taaaaaaaaa gaggttattt
      301 tttctaggag tttttacttt tgagataact tctttttttt aagaaatttg tagtataata
      361 gaaaaagata aaaaataaat gtaaataagt ataaaactag aatgtaaaag tgaaaaatag
      421 atatagatat ttaaaagctt atatttagtt aatgttcttt agtttgtcta aagagaatta
      481 taggaggtac tgtagtatga aagcaaggtt aatattagaa gatggaacag tttttatagg
      541 aaaggcattt ggatatttag aagaaagtgt aggagaagta gtatttaata cttcgatgat
      601 aggatatggt gaagttttaa cagacccttc ttactatggt caaatagtta ctatgactta
      661 tcctcttgta ggaaattatg gtataaattt atcatcagca gagtctgaaa aagttcaagt
      721 aaagggattc atagtaaggg agaaaagtga ttctccaagt aattttagat gtgaaattga
      781 tatagaccaa tatttaaagc aaaataaagt tatcggactt gaaggaatag atacaagagc
      841 tttgactaag atacttagaa ataatggaac aatgaaaggt ataattacat tagaagacag
      901 taaattagaa gatgttaaac ataaattgga taagttttca aatacagaag cagttagaac
      961 tgttacaaga aaagaagtag agcatataaa aggaaatggt ccaaaagtgg ctgttatgga
     1021 ttttggagta aaaagaaata tattaagatc atttatagct cgtggatgtg atataacaat
     1081 atttccagct acaacatctc cagaagatgt attgagtata aaccctgact taatattctt
     1141 gtcaaatgga cctggagacc cagaagacct agaagatgtt atagaaaata taaaagctct
     1201 tattggtaaa aaacctatag ttggaatatg cttaggacat caacttttag ctttagctct
     1261 tggaggaaaa actgctaaac ttaaatttgg gcatagaggt ggaaatcatc cagttaaaga
     1321 tttagaagaa ggaaaagtat ttataacttc tcaaaatcat ggttattatg tttcagaagt
     1381 tcctgaacaa atgaaagtga cacatataaa tttaaatgat aatactgttg aaggaatgag
     1441 acatgagaag ctagatgtat acagtgttca ataccatcct gaagcttgcc caggaccaaa
     1501 agataatgac tatatttttg ataaattttt agaattagta aaataaataa cattagaata
     1561 gctaactaaa aaacaagaat aacttaaatc aaaaagtttg gtttaattaa catagatgta
     1621 ttaaatagat gtattgatga gtaaatttga acttaagata aaataaagta attaaagttg
     1681 attgtataga tgatgaagat aagaactgtg aaaattgttt agataaggag aaagagttat
     1741 gcctaaatta gatagtataa agaaaacttt agtattaggg tcagggccaa taataatagg
     1801 tcaagctgca gagtttgact attcaggaac acaggcctgc caagcattaa aagaagaggg
     1861 aattgaagtt gtattagtaa atagtaaccc agctactata atgactgata aagaaattgc
     1921 agataaaata tatatagaac cattaacaat agaatttata gaaaaaataa tagaaaaaga
     1981 aagaccagac agtttacttg caggtatggg tggtcagaca ggattaaact tagctgtaga
     2041 attacatgat gctggtatat tagataaata taatgtaaaa gttataggaa catctataga
     2101 atctataaaa aagggcgaag atagagattt atttagagaa gtaatgaaag aaataaatca
     2161 accagtaata gttagtgata tagttacaaa tttagaagca ggtcttgagt ttgccaataa
     2221 gataggatat ccagtagttg taagaccagc atatacgcta ggtggaactg gtggaggtat
     2281 agctgatact gaggaagaat taagagaaat actttcacat ggactacagc taagtcctgt
     2341 tggacaagtt cttcttgaaa agagtataaa aggttggaaa gaaatagaat atgaagtaat
     2401 gagagatgga aatggaaact gtataactgt atgtaatatg gaaaatgtag acccagttgg
     2461 agttcataca ggagacagta tagttgttgc tccaagtcaa actctaagtg atgaagagta
     2521 tcaactactt agaaaggcat caatagacat aataaatgca atagaggttc aaggtggatg
     2581 taacgttcaa atagctttaa acccacatag tttagaatat gcgataatag aaataaaccc
     2641 aagagttagt aggtcatcag ccctagcatc aaaagctaca ggatacccaa tagcaaaagt
     2701 agcagctaag atagctttag gttatacttt ggatgagata gaaaatgcag taactaaaaa
     2761 aacttatgct tgttttgagc caacattaga ttatgtggta gtaaaaatac caaagtggcc
     2821 atttgataaa tttagacatg caaatagaaa attaggaact aagatgatgg caactggtga
     2881 aatcatgagt ataggaagta actttgaggc tgctattctt aaagggataa gatcacttga
     2941 aacaggaaaa tattcattgg ttcatgctcc atcagaaggt agaacattag aagaattaaa
     3001 ggctagagta gtagtacctg atgatgagag actatttgac ttagctgaaa tgataagaag
     3061 aggctataaa gtagaaatga tatcagaaat aactggtgtt gataagtggt ttataaataa
     3121 atttaaatgg atagtagaac aagaagaaaa gttaaaagtt ctaaaaatag aagacttaga
     3181 taaagaatat ttacatgaat taaagaaaaa gggattttct gataaaggta tatctgactt
     3241 aatgaagata agcccagaaa aattatatga attgagaagt ttatataata tacaaccagt
     3301 ttataaaatg gttgatacat gtggaggaga atttgaagct ctatcacctt attactattc
     3361 aacttatgaa caatatgatg aggtagtagt tagtgataag agaaaagttg tagtattggg
     3421 ttctggtcca ataagaatag gtcaaggtat agaatttgac tattgttcag ttcactgtgt
     3481 aaaatcttta agaaaaatgg gaatagaaac tataattgta aacaataacc ctgaaactgt
     3541 aagtacggat tttgatacat ctgataagtt gtattttgaa ccattaacag aagaagaagt
     3601 tttaaatata atagaaaaag aaaaaccaga aggtgtaata ctacagtttg gtggacaaac
     3661 agctataaaa ttggctaagt ttttacatga aaaaaatata cctatactgg gaacagactt
     3721 tagagatata gatgcagcag aagatagaga aaaatttgat gatttactag agagactaga
     3781 tataaataga ccaaaaggaa aaggtgtatg gacaactaat gaaggtgttg aaattgctaa
     3841 ggagttaggt tatccagtat tagttagacc atcttatgta cttggtggtc aaggtatgga
     3901 aataacttat aacgaagaaa aactaattca gtatttgga
//
LOCUS       DAMJYN010000179         3871 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.185, whole genome shotgun sequence.
ACCESSION   DAMJYN010000179 DAMJYN010000000
VERSION     DAMJYN010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3871)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3871)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3871
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.185"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            128..1618
                     /locus_tag="PC466_003649"
     CDS             128..1618
                     /locus_tag="PC466_003649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HDF2770996.1"
                     /translation="MFQFETQIHKLRHDVLTAIARLGKEDNLTREAMDNIQYEIIKGE
                     KPTYRCCVYKERAIISERVNVSMGLQPGQDKIDLDTMDIEEDEQIIYILEAACDSCPI
                     NEFTVTDICRGCLAHRCKEACKFGAITHVGGMAYINHELCKACGMCKKACQYDAISEV
                     VRPCKSVCPTNALGFDRENMKAMIHEDKCLNCGACMSACPFGAISDKSLIAPVARKLV
                     QKEKMYAVVAPAITGQVEANVTYGQIKNAIKSLGFVDVLEAACGADAVTVHESLEFAE
                     RMEKGEAFMTNSCCPGFVGYIEKTYPNHVGKISSTVSPMIASGRFIKSHEPDAKVVFI
                     GPCTAKKSEAAKKELKGAVDYVLTFEEIMALFEAFDIDLAKCSNEDIDDASIFGRGFG
                     AAGGLTKAIENYLAEKGIGVNFEPVKISGSREIKKTMTMANLGKLEGNFIEGMMCEGG
                     CINGSGKFLSGAKVKATFDRKNSQSTKKSVLANTKIKDFSNINLEK"
     gene            1876..3372
                     /locus_tag="PC466_003650"
     CDS             1876..3372
                     /locus_tag="PC466_003650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HDF2770997.1"
                     /translation="MFEFETQLKRLKHEVLTAVARLSIEENLTKENIEKIPYEIIKGE
                     KARYRCCVYKEREVVLERAQLALSLTPNSKYGDINPDSVSLDTDEQIIYIVEAACDRC
                     PINEFTVTELCRGCLAHRCKEACKFGAISYINGRAYINHDLCKACGMCKSSCQYDAIS
                     EVVRPCKSVCPTGALDFNRNTMKAMIHEDNCINCGACISACPFGAISDKSLIAPVAKK
                     LAKKENMYAIVAPAITGQIDSNITYGQLKNAIKSLGFVDMIEASCGADAVTVHESNEL
                     IERIKSGDNYMTNSCCPGFFKYIEKMFPDEKDRISSTVSPMVATGRLVKKIDSDAKVV
                     FIGPCTAKKSEATEKSLKDSVDYVLTFEELMALFEAFNIDLSKCSNEDINDGSIFGRG
                     FGASGGLAKSVQNYIAEKGLSFEFEPIKVSGPRQIKKTMTMAKLGRLEGNFIEGMMCE
                     EGCINGAGKFLSGVKAKNTFDRKNGQSTKKSVLSNDKIKEFEDVNLER"
     gene            3506..3856
                     /locus_tag="PC466_003651"
     CDS             3506..3856
                     /locus_tag="PC466_003651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF2770998.1"
                     /translation="MKKIVLKDILFLVTTLSIIVILLFVTNITTNSKIKSTSESYLKS
                     DKNSVRQNGIQRSTKNTAFKTTILSTGKSDCILIEIGDKFIMIDTGEDKNGEQIVDKL
                     KEKEINALDYLIKK"
BASE COUNT         1527 a          396 c          763 g         1185 t
ORIGIN      
        1 taaaaaaaca ctatatatat tcgataaaat aaaatttaaa catataatat tttatgtata
       61 tattaataaa aggacatatt gtgttataat ggtatcgtat aaaatcattt acgggggtgg
      121 tattaaaatg tttcaatttg aaacacaaat acacaaatta agacatgatg ttttaactgc
      181 aatagctaga cttggaaaag aagataacct taccagagaa gcaatggata atattcagta
      241 tgaaataata aaaggtgaga aacctacata cagatgttgt gtttataaag aaagagctat
      301 aatatctgag agagtaaatg taagtatggg gttacaacca ggtcaagata agatagattt
      361 agatacaatg gatatagaag aagatgaaca aattatatat attttggaag ctgcatgtga
      421 cagttgtcca ataaatgaat ttacagtaac agatatttgt agaggatgtc tagcacatag
      481 atgtaaagaa gcttgtaaat ttggagctat aacacatgtc ggaggaatgg cctatataaa
      541 tcatgaatta tgtaaggctt gtggaatgtg taaaaaagct tgtcaatatg atgccatctc
      601 agaggttgtt agaccatgta agagtgtttg tccaactaat gccttaggat ttgatagaga
      661 aaatatgaaa gctatgatac atgaggataa atgtttaaac tgtggagcat gtatgtcagc
      721 atgtccattt ggagcaatat ctgataagag tttgatagct cctgtagcta gaaagttggt
      781 tcaaaaagag aaaatgtatg cggtagtagc tccagctata acaggtcaag ttgaagcaaa
      841 tgttacatat ggtcaaataa aaaatgctat aaaatcacta ggatttgttg atgtattaga
      901 agcagcttgt ggagcagatg cagttacagt tcatgaaagc ttagaatttg ctgaaagaat
      961 ggaaaaggga gaggctttta tgacaaattc ttgttgtcca ggatttgttg gttatataga
     1021 aaaaacatac ccaaatcatg taggaaaaat atcttctaca gtgtctccta tgatagctag
     1081 tggtagattt ataaaaagtc atgaaccaga tgctaaagtt gtattcatag gaccatgtac
     1141 agccaaaaag agtgaggcag ctaagaaaga attaaaagga gctgttgatt atgtacttac
     1201 ttttgaagaa ataatggcat tatttgaggc atttgatata gacttggcta agtgttcaaa
     1261 tgaagatata gatgatgcat caatttttgg aagaggtttt ggagctgctg gtggtcttac
     1321 aaaagctata gaaaattatc ttgctgaaaa aggtattggt gttaattttg aacctgtaaa
     1381 gatttctggt tcaagagaaa tcaagaaaac tatgactatg gctaatttag gaaagctaga
     1441 aggtaatttt atagaaggaa tgatgtgtga aggtggttgt ataaatggtt ctggtaaatt
     1501 cttatcaggt gcaaaggtta aagccacttt tgatagaaaa aattctcaat caactaagaa
     1561 aagtgtctta gcaaatacaa agataaaaga ttttagtaat ataaatttag aaaaataaag
     1621 ataatacaaa gcaacaaaaa tacatattgt taatagagtt gttctaagtt gaggtttaac
     1681 ttttggacaa ctctattttt atttatatat ttaattaatg aacaactaaa ataaaaatta
     1741 catatataat attttgtata taacttaaca aagtatatgc ctatgttata ataatttata
     1801 gaaataaata aaaaatacaa tatacataat agtagaaata tagtaaaaag gtgtgattta
     1861 tagggaggat tacttatgtt tgaatttgaa acgcaactaa aaaggttgaa acatgaagtt
     1921 ttaacagcag tagcaagact atctattgaa gaaaatttaa caaaagaaaa tatagaaaaa
     1981 attccatatg aaataattaa aggagaaaag gcgagatata gatgttgtgt ttataaagag
     2041 agagaagtag ttcttgaaag ggcgcaactt gcattaagtt taactccaaa tagtaaatat
     2101 ggagatataa atccagattc agttagtttg gacacagatg agcaaattat atatatagtt
     2161 gaagcagcat gtgatagatg tccaataaat gaatttacag ttacagagct ttgtagaggg
     2221 tgtttggctc atagatgtaa ggaagcatgt aaatttgggg caatttctta tataaatggg
     2281 agagcatata taaatcatga tttatgtaag gcttgtggaa tgtgcaaaag ttcatgtcaa
     2341 tatgatgcta tatcagaagt tgtaagacct tgtaaaagcg tttgtccaac aggagctttg
     2401 gattttaata gaaacactat gaaagcaatg atacatgaag ataattgtat aaattgtgga
     2461 gcatgtatat cagcatgtcc ttttggagca atatctgata agagtttgat agcacctgtt
     2521 gcaaaaaaac ttgcaaagaa agaaaatatg tatgcaatag tagctccagc tataacaggt
     2581 caaatagata gtaatattac atatggtcag ttaaaaaatg ctataaaatc acttggattt
     2641 gtagatatga tagaagcttc ttgtggagca gatgcagtta cagttcatga aagcaatgag
     2701 cttattgaaa gaataaaatc aggagataat tacatgacaa attcatgttg tccgggattt
     2761 tttaagtata tagagaagat gttcccagat gaaaaagata gaatatcatc tacagtgtct
     2821 cctatggtag caacaggaag attagtaaaa aaaatagatt ctgatgctaa agttgtattt
     2881 atagggccat gtacagctaa aaagagtgag gcaacagaga aaagtttaaa agattcagta
     2941 gattatgtac ttacttttga agaactaatg gcattatttg aagcatttaa tatagattta
     3001 tcaaaatgtt caaatgaaga tataaatgat ggttcgattt ttggaagggg atttggagcg
     3061 tctggtggac ttgccaaatc agtacagaac tatattgctg aaaagggact tagttttgag
     3121 tttgaaccta taaaagtatc tggtccaaga caaattaaaa agacaatgac aatggctaaa
     3181 ttgggaagat tagaaggtaa ttttatagaa ggaatgatgt gtgaagaagg ttgtattaat
     3241 ggagcaggta agtttttatc aggtgtaaaa gctaaaaata cttttgatag aaaaaatgga
     3301 caatctacta aaaagagtgt tttatctaat gataagatta aagaatttga agatgtaaat
     3361 ttagaaagat aattgttttg gtacagtcat ttttttatca tgccacaaat atgcctaaaa
     3421 ttttcccttt ttatatgtgt attttacaga gttaaggttg ctatactata aatatgtaat
     3481 aaataaaatt tataggagct tttggatgaa gaaaatagta ttaaaagata tcctgttttt
     3541 agttactaca ttatctataa tagtaatatt attgtttgta acaaatataa ctactaatag
     3601 taagataaaa tcaacaagtg aatcttattt aaaaagtgac aaaaatagtg tgaggcaaaa
     3661 tggtatccag aggagcacaa aaaatactgc atttaagact actatattaa gtactggaaa
     3721 gtctgactgt atattaatcg agataggtga taaattcata atgattgata caggagaaga
     3781 taaaaatgga gaacaaatag ttgataaatt aaaagaaaaa gaaataaatg cacttgacta
     3841 tttgattaaa aaatagctac gcacactcgt g
//
LOCUS       DAMJYN010000180         3831 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.186, whole genome shotgun sequence.
ACCESSION   DAMJYN010000180 DAMJYN010000000
VERSION     DAMJYN010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3831)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3831)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3831
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.186"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            109..1221
                     /locus_tag="PC466_003652"
     CDS             109..1221
                     /locus_tag="PC466_003652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDF2770999.1"
                     /translation="MNAFIRKRNKNYVVYLEFEDEKTGKRKQKNMGTFDKKREASKRL
                     NEVKESLYNDGFLVPSEITVSEFLLDFLNKYSENISLATYNNYVSICKNYINPSIGKY
                     KIQDLHPVHIQNYIDKLSYKLNPQSIKIHINILKLAIKRAYRLKLIKENVMDSIEAPR
                     YKKFKNEIYDREQMIKLLDLAKNTEMELPINLAIGLGLRISEVLGLTWDNIDFEENTI
                     TVNKITSRINGSVILKEPKTESSVRKISSPKELMSLLKEYKIKQNKNLLKSSIRNNNN
                     LLFFNKKCEPIAEDVMSKKFKRFLEKNELPHIRFHDLRHSHVTLLINSKVPIKVISER
                     VGHSNISTTLSVYSHVLKEMDKEASDKISESLFNAN"
     gene            complement(1429..1905)
                     /locus_tag="PC466_003653"
     CDS             complement(1429..1905)
                     /locus_tag="PC466_003653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2771000.1"
                     /translation="MVKKRLVAVVLSLAMISVGNFSYAHSGGHNSSGGHHNKNKSELT
                     RYYCGGHSAHQPNKGFCPYASTKENSGVTISSVHNEKNHKNYFAEKGYNKGYEDGCKG
                     LYNLSVTEAKSDNLYEKEILKSSYEKGYLIGYNEYKAKKVDDVMKKMLDIPMLASI"
     gene            complement(2104..3729)
                     /locus_tag="PC466_003654"
     CDS             complement(2104..3729)
                     /locus_tag="PC466_003654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF2771001.1"
                     /translation="MLQVTGVGLRFGDKELFKDVNLKFTKGNCYGIIGANGAGKSTFL
                     KILSGEIEPNTGSISITDKERMSVLKQDHFEYEEETVLNVVIRGHERLWNIMKEKDAL
                     YMKEDFNEEDGIKAAELEGEFAELDGWDAETNAEKILMGLGITKDMHYKQMKELVGGE
                     KVKVLLAQSLFGKPEILLMDEPTNHLDFKSINWLNNFIMDLEESIVIIVSHDRHFLNQ
                     ICTNIVDVDFGKIQMYVGNYDFWYESSQLALQLAKDQNKKTEEKIAQLKEFIARFSSN
                     ASKAKQATSRKKQLEKLEVEDIQPSRRRYPYVGFTPAREIGNEVLEVHNLTKTIDGVK
                     VLDNVSFRLDRDDKVVFMGDEIATTALFNIVMGELEPDSGEYKWGVTTSQDYLPKNHN
                     KFFDGVEYSLVDWLRQFSEEKSESFIRGFLGRMLFSGEEALKEAQVISGGEKVRCMLS
                     KLMLSNANVLVLDDPTNHLDLESITSVNKGLEKFPGVLLFTSHDHEFISTIANRIIEI
                     TPNGIMDRKMDFDEYLESKEIQDQLAKMYGKDK"
BASE COUNT         1337 a          613 c          425 g         1456 t
ORIGIN      
        1 aaataaatat atacaatgta ttaaaatgta tgcaactcta tttcaaaatt attttgtgat
       61 atatatatgt tataataaat gtataaaatt ttgattggtg ggttatatat gaatgcattt
      121 attagaaaaa gaaataaaaa ctatgttgtt tacctggaat ttgaagatga aaagacaggt
      181 aaaagaaaac aaaaaaatat gggtactttt gataaaaaaa gggaagcaag taaaagacta
      241 aatgaggtaa aagaaagctt atataatgat ggttttttag taccaagcga aattacagtg
      301 tcagaatttc tattagattt tctaaataaa tatagtgaaa atatatcttt agctacatat
      361 aataattatg ttagtatttg taaaaattac attaatccat ctattggaaa atataaaata
      421 caagacttac atccggttca catacaaaac tacatagata aactatctta taaactaaat
      481 cctcaatcaa ttaagattca tataaatata ttgaaacttg caataaaaag agcttataga
      541 ctcaaattaa taaaagaaaa tgttatggat agtatagagg ctccaagata taaaaaattt
      601 aaaaatgaga tttatgatag agaacaaatg ataaaattat tagatttagc aaaaaataca
      661 gaaatggaat tacctattaa tttggctatt ggattaggtc ttagaatttc agaagtttta
      721 ggtctaactt gggataatat tgattttgaa gaaaatacaa taacagtaaa taagataact
      781 tcccgaatta atggttctgt tattctcaaa gagccaaaga cagaaagctc tgttagaaaa
      841 atatcttctc ccaaagaatt aatgtcttta ttaaaagaat ataaaataaa acagaataaa
      901 aatttattaa aatcttccat tagaaataat aataatttgt tgtttttcaa taagaaatgt
      961 gaacctattg ctgaagatgt tatgagtaaa aaatttaaaa gatttttaga aaagaatgaa
     1021 ttacctcata ttagattcca tgatttaaga cactcacatg ttactttact tataaattct
     1081 aaagtaccta taaaggttat atccgagaga gtaggacact caaatataag tactactcta
     1141 agcgtttatt ctcatgtact taaagaaatg gataaagagg cttctgacaa aatttctgaa
     1201 agtttattta atgctaatta atattaattt atcttagctt taaattagct tagcttattg
     1261 agatagattc attaatatta aatgtatcta tctcaaatta ataactactt aaataatctg
     1321 ttttatttta atttatcgcc tcagttatta tactttttta tgaaaaatta tactttacaa
     1381 taaaaaagat atttccttat agaaagtatc tttttaaata ctattttatt atatacttgc
     1441 taacattgga atatctaaca tcttcttcat tacatcatct actttttttg ctttatattc
     1501 attgtatcca attaaatatc ctttttcata tgaacttttt aaaatctctt tttcatataa
     1561 attatcagat ttggcttctg tgacacttaa attataaagc cctttacacc catcttcata
     1621 acctttatta tacccttttt ctgcaaaata gtttttatga tttttttcgt tatgtactga
     1681 agatattgtt actccagaat tttcttttgt actagcataa ggacaaaaac ctttatttgg
     1741 ttgatgtgct gaatgtcctc cacaataata acgtgttaac tctgatttat ttttattatg
     1801 atgacctcct gatgaattat gccctcctga gtgagcatat gaaaaattcc ctacactaat
     1861 catagctaaa ctcaatacta cagctactaa ccttttctta accataatct attcccccca
     1921 aaatgttata tatttttatt atatcatcta ctatattata tttaaattct taatatacaa
     1981 aatattactc gattctgcta ataaacatat ttaaacaaca taaaaaacct cctaatattt
     2041 gattaaaaat ttacacactc atgcatagca tgtatcaaat attaaaaggt tttatactaa
     2101 taattattta tcttttccat acattttagc taattggtct tgtatctctt tactttctaa
     2161 atactcatca aagtccattt ttctatccat tattccattt ggagttatct ctataattct
     2221 atttgctata gtagatataa attcatggtc atgagaagta aataaaagca ctcctgggaa
     2281 cttttcaagt cctttattta cagaagttat actttctagg tctaagtggt tagtagggtc
     2341 atctaataca agtacatttg catttgaaag cattagctta ctaagcatac atctaacctt
     2401 ttctcctcca gatataactt gagcttcttt taatgcttct tcacctgaga ataacattct
     2461 acctaaaaat cctcttataa aactttcact tttttcttca gagaactgtc taagccagtc
     2521 aaccaaagaa tattctactc cgtcaaaaaa cttattatga ttttttggaa gataatcttg
     2581 agaagtagtt actccccatt tatactctcc actgtctggt tcaagttctc ccataactat
     2641 gttgaaaagt gcagtagtag ctatttcatc tcccataaat actactttat catctctatc
     2701 caatctaaat gacacattat caagaacctt aaccccatct atagttttag ttaaattgtg
     2761 tacttctaaa acttcattcc caatttctct tgcaggtgta aatcctacat atggatatct
     2821 tcttcttgat ggttgtatat cttcaacttc taatttctct aactgtttct ttcttgatgt
     2881 tgcttgttta gcctttgaag cattagaact aaatctagct ataaattcct ttaattgagc
     2941 tatcttttct tcagtctttt tattttggtc cttagccagt tgtaaagcca attgacttga
     3001 ctcataccag aaatcatagt ttccaacgta catttgtatt ttaccaaaat ctacgtcaac
     3061 tatattagta catatttgat ttaggaaatg tctatcatgt gatactatta taactataga
     3121 ctcttctaaa tccattataa aattatttaa ccagtttatt gatttaaaat ctaagtggtt
     3181 tgtaggttcg tccattaata gtatttcagg cttaccaaaa agtgattgtg ctaacaatac
     3241 cttaaccttt tccccaccaa ctagttcctt catttgtttg taatgcatat ctttcgttat
     3301 gccaagaccc ataagtattt tctcagcatt agtttctgca tcccatccgt caagctctgc
     3361 aaactcacct tcaagttcgg cagcttttat cccatcttct tcattaaagt cttccttcat
     3421 atacaatgca tctttttctt tcattatgtt ccaaagtctc tcatgacctc ttataacaac
     3481 atttaaaaca gtttcttctt catattcaaa gtggtcctgt tttaaaactg acattctttc
     3541 tttatcagtt atagatatac tacctgtatt aggctctatt tctcctgata atatttttaa
     3601 aaaagtagat tttcccgcac cattagctcc tattattcca tagcaattac ctttagtgaa
     3661 ttttaagtta acatctttaa atagttcctt atcaccaaat ctaagtccaa cacctgtaac
     3721 ttgtaacatt aatatatttt cctttctttt tgctcataat ttattttatc ataaaacttt
     3781 gataacattt ttattatata ttatcacgta aatagtatat tttttatact a
//
LOCUS       DAMJYN010000181         3807 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.187, whole genome shotgun sequence.
ACCESSION   DAMJYN010000181 DAMJYN010000000
VERSION     DAMJYN010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3807)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3807)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3807
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.187"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            31..699
                     /locus_tag="PC466_003655"
     CDS             31..699
                     /locus_tag="PC466_003655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2771002.1"
                     /translation="MENITSYFTTILCVFICLSSVFIFTQLARVFINKKKINQKIKSR
                     NGFRYDRDFIEARREEIHIKDNNNNKNKSNNKKLKEEKVFKYDNGDLYKGEFVDGKKN
                     GFGIYIFSSKEKYEGLWKDDKMHGIGKYTYRDGSIYTGEFKYGLKNGLGKLTYPNNDI
                     YKGYFLDNKKNGKGVLYKNDGNKQAGIWENDEQCKSLDFKDLNNNKINNVYQNRLNNN
                     KLKV"
     gene            858..1364
                     /locus_tag="PC466_003656"
     CDS             858..1364
                     /locus_tag="PC466_003656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HDF2771003.1"
                     /translation="MKEYVVVDLETTGLDPYKGCEIIEIGITEIKNEQIVKNYSRLIK
                     PKGIISSFITELTHISNEMVENEEPLELVLPRFRKYIGDRTIIAHNAKFDLKFLNYYL
                     RMLDLEPINNYICTVELLKKCKSYKGKNKKLETACAYYNIENINAHRADSDTLATAKL
                     FLKIKDEY"
     gene            1492..2508
                     /locus_tag="PC466_003657"
     CDS             1492..2508
                     /locus_tag="PC466_003657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase domain-containing protein"
                     /protein_id="HDF2771004.1"
                     /translation="MGYYNDNDNNKIRRKKISNNKDSNKKSKHSYTSANKKNKSPNTS
                     SSKRMSEKVDSQNLIKRDRDSFTRDNVRPLNTDYNQRERRRVEYKQREKKLKSKKRKK
                     QKRIRIVRALLSIMLVALIIFSVAGAIFTVSAIKGSPEVTKKLIRSKYISSEVVSIKQ
                     MPNDLKHAIVSIEDERFYKHKGVDVISLVRSVLNNVFTDTTQGASTIDMQVSKNLLTS
                     NDKTMKRKIRDMYNAKQMNKIMTKDEILEAYLNNMYLGKNAYGAAKGAEVYFGKKVSE
                     LNLAECAMLAGMTNNPARYIDHGEAKKRQVIVLYKMHQLGYITDKEYRIAKADDTPFK
                     SEID"
     gene            2862..3566
                     /locus_tag="PC466_003658"
     CDS             2862..3566
                     /locus_tag="PC466_003658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="B3/4 domain-containing protein"
                     /protein_id="HDF2771005.1"
                     /translation="MKKFVIEDAFWNLFPSAKIGVIICNDIDNSIKDEDYKKIILKGE
                     EEALKYLEDSEFSNNQVIKVWREAFKKFKTKKGARSSIEALLKRVHNGNNIGTINPLV
                     DIYNFISLKYALPCGGEDIDKFIGDIRLTRAIGNEEFIPLGTDENSFPYEGEIIYKDD
                     GGAICRCWNWREAVRTMLTEDTNNAFLCIELVDESRFKEFENALNELAKIVQEKLGGN
                     CKISILDIDNKEVSVD"
BASE COUNT         1634 a          325 c          653 g         1195 t
ORIGIN      
        1 ttaaataaat tttttaaagg gtgatttttt atggaaaata taactagtta ttttacaaca
       61 atactatgtg tatttatatg cttatcatct gtatttatat ttactcaact agctagagta
      121 tttattaata agaagaagat taatcaaaaa attaaatcaa gaaacggatt taggtatgat
      181 agagatttta ttgaagccag aagagaagaa atacatataa aggataacaa taataataaa
      241 aataagagta acaataagaa attaaaggaa gaaaaagtat ttaaatacga taatggtgat
      301 ttatataaag gtgagtttgt tgatggaaag aaaaatggat ttggaatata tattttttca
      361 agtaaggaaa agtatgaagg attatggaaa gatgacaaga tgcatggaat aggaaaatat
      421 acttatagag atggttcaat atatacaggt gaatttaaat acggattaaa aaatggtttg
      481 ggaaaattaa catatcccaa taatgacatt tataagggat attttttaga taataagaaa
      541 aatggtaagg gtgtattata taaaaatgat ggaaataaac aagcaggaat atgggaaaat
      601 gatgaacaat gtaaaagttt agattttaaa gatttaaata ataataaaat aaataatgtt
      661 tatcaaaata gattaaataa caataaatta aaagtttaat tattctaata aaaaaatctt
      721 tatttatgat ggaatatagg atatatctat gttgtaattt gtaaaatctt cctatatcat
      781 ataaaattaa gtattgatta gtctattaca taaatataga atataaatat atccatttaa
      841 taataaggag aagagatatg aaagaatatg tagttgtgga tttagaaact acaggattag
      901 atccatataa aggttgtgaa ataatagaaa taggaataac agaaataaaa aatgaacaaa
      961 ttgtaaaaaa ctattcaagg ttgataaaac ctaaggggat aatttcttca tttataacag
     1021 aattgacaca tataagtaat gaaatggtag aaaatgaaga accactagaa ttagttttac
     1081 ctagatttag aaaatacata ggtgatagaa ctataattgc acacaatgcg aaatttgatt
     1141 taaaattttt aaattactat cttaggatgt tagatttaga accaataaac aattatatat
     1201 gtacagtaga attattaaaa aaatgtaaaa gttataaagg aaaaaacaag aaacttgaaa
     1261 cagcttgtgc ttattacaac atagagaata taaatgctca tagagctgac agtgatacat
     1321 tagcaactgc aaaactattt ttgaaaataa aagatgaata ttaattataa atatagagaa
     1381 aattagtgaa aatatccttt ataaaattga cccttaagct tacaattttg ttctttgatt
     1441 tattttgtag aacaatgtat aatgtacctt atatgaagaa gggagactaa aatgggttat
     1501 tacaatgata atgataataa taaaataaga cgtaaaaaaa ttagtaacaa caaagatagt
     1561 aataaaaaat ctaaacattc ttatacttcg gcaaataaaa aaaataaaag tcctaataca
     1621 agttccagta aaagaatgag tgaaaaagta gattcacaga atcttataaa aagagataga
     1681 gatagtttta caagagataa tgtaagacct ttaaatacag attacaatca aagagaaaga
     1741 agaagagtcg agtataaaca aagagagaaa aaattaaaaa gtaaaaaaag aaaaaaacaa
     1801 aaaaggatta gaatagttag ggcattatta tctattatgt tagttgcact aattatattt
     1861 tcagtggcag gtgcaatatt tacagtttca gctataaaag ggtcaccaga agttactaaa
     1921 aagttaatta ggtctaaata tataagtagt gaggttgtaa gtataaaaca aatgccaaat
     1981 gatttaaaac atgcaatagt ttccatagaa gatgagagat tttataagca taaaggagta
     2041 gatgttattt ctctagttag gtcagtatta aacaatgtgt ttacagatac aacacaaggt
     2101 gcaagtacta tagatatgca agtttcaaaa aacctgctta ctagtaatga taaaactatg
     2161 aagcggaaaa taagggatat gtataatgct aagcagatga ataagattat gactaaggat
     2221 gaaattcttg aggcatattt aaataatatg tatctaggta aaaatgcata tggagctgca
     2281 aagggagctg aagtctactt tggtaaaaaa gttagtgaat taaatttagc tgagtgtgct
     2341 atgttagctg gtatgacaaa taatcctgca aggtatattg accatggaga ggctaagaag
     2401 agacaagtga ttgtactgta taagatgcat cagcttggtt atataactga taaggagtat
     2461 agaatagcaa aagctgatga cactccattt aaatcagaaa ttgattaaaa ttgtaagaat
     2521 atagtatttt caatagttta aacaaacaaa aatgtaataa aaaaggtgat ttgccaccca
     2581 tttgccacca taattataat ctaatggcaa attgttttaa tgtacaaact agataataga
     2641 atattgtttt aaatgctata ttatgctaaa atttaattgt attttgtaaa ttaaaaaact
     2701 tataatttag ttttctaggg ttccgcattt tataatggtc aggtccaaga gaaaacgcgc
     2761 aattgttgtg tacacggaag gataaaagcc tgggagatat ttaataatat ttctataggc
     2821 ttttttattt ttacatattt taaatttgag gaggttttct aatgaaaaaa tttgttattg
     2881 aggatgcatt ttggaatcta tttcctagtg caaaaattgg agttattatt tgtaatgata
     2941 tagataactc tataaaagat gaagactata agaaaataat tttgaaggga gaagaagaag
     3001 cattaaaata cttggaggac tcagaattta gcaacaacca agtgattaaa gtatggagag
     3061 aggcatttaa aaaatttaaa acgaaaaaag gagcaaggtc ttctattgaa gcattattaa
     3121 aaagagttca taatggaaat aatataggaa ctattaaccc tttagtggat atctacaatt
     3181 ttatctcatt aaaatatgca ttaccttgtg gaggggagga tatagataaa tttataggag
     3241 atattaggct aactagagca attggtaatg aggagtttat cccactaggg acagatgaaa
     3301 attcatttcc atatgaagga gaaataattt ataaagatga tggtggagca atttgtagat
     3361 gttggaattg gcgtgaagca gtgagaacaa tgcttactga agatactaac aatgcctttt
     3421 tatgcattga attagtagat gaaagtagat ttaaagaatt tgaaaatgct ttaaatgaat
     3481 tagctaaaat agttcaagaa aaattgggtg ggaattgtaa aatttcaatt ttagatattg
     3541 ataataaaga ggtatcagtg gattaatctg gagatgctgt tgtaatggac tattctagtt
     3601 ataaagatac ttatatttag ggtaataagt tctattttag atgtaacgat tatcaaagga
     3661 tataatatag aaaataaaaa tgtagaatat aaaaagcctt taaaataaga aaaaaatgta
     3721 ttttaaaggc ttttattata ctctttttta tttgcataat taacaataaa aatatattgt
     3781 taattataat atttttattg aaaaacg
//
LOCUS       DAMJYN010000182         3470 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.188, whole genome shotgun sequence.
ACCESSION   DAMJYN010000182 DAMJYN010000000
VERSION     DAMJYN010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3470)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3470)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3470
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.188"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            116..1714
                     /locus_tag="PC466_003659"
     CDS             116..1714
                     /locus_tag="PC466_003659"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative manganese-dependent inorganic
                     diphosphatase"
                     /protein_id="HDF2771006.1"
                     /translation="MSLLVFGHKNPDTDSICSAISLAHLKNKLGIKATAYALGDIRKE
                     AKYALDYFKVDAPEILDNVRIQVRDLNYDKVVPLTPTSSILEAYNLMDEKNVKTLPVT
                     YDDGTFAGIITMKEIAKNLLHQHFTTIHTSLSNICKNLNGTILVDCGEDIKGRVVTLS
                     FGMETLIETLKEGDIAIVGDRYDSIEYAIDTKVKLLILTNHTEISKDLLALAKINGVS
                     VVSVESDNYKTSNVINQCSFLDSIEATENLITFKEDDYMDEIKEIMLETNFRSYPILD
                     DDNKFLGLVSKGHLLNPSKKNVVLVDHNEYAQSADGIEQANIVEIIDHHKLGGISTDV
                     PMSFRVMPVGCNSTIIYQMYKENNVEIPYEIAGLLLSAILSDTLLFKSPTTTDMDKKA
                     CEELSKIAKVDMEKYAMDMFKCGTSLDEYTIEEIVNMDFKEFNMSGHRVGIGQVFTLD
                     IDSIFAKKDEFLSYINSTDYDKLILAVTDIIKEGSYLIYKAEDSLIANAFDVEGVQGT
                     FAPGVVSRKKQLVPNLTTAIKNFK"
     gene            complement(1949..2140)
                     /locus_tag="PC466_003660"
     CDS             complement(1949..2140)
                     /locus_tag="PC466_003660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exosporium protein"
                     /protein_id="HDF2771007.1"
                     /translation="MAGLTTEPGGGGVLSGYFAGFLFGGTTFTINNFSSTTVGIRNGQ
                     SAGTAATLTIFRIADTVMT"
     gene            complement(2309..2902)
                     /locus_tag="PC466_003661"
     CDS             complement(2309..2902)
                     /locus_tag="PC466_003661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like protein"
                     /protein_id="HDF2771008.1"
                     /translation="MRIPDILKDKSILKAELFIHIDSNKNHIFKEKVDIEIKRISEYY
                     NLRTITWNDRVSMENIRGYLPIGISDTSNYICLNITGTIKAWAMNKYPNYGLALSLNY
                     PYQIFEFTSSRDCNKPYILVTFEDRIIDNCYPKCECLPIRITGPMGPRGATGSIGPMG
                     ATGPTGATGNSSQPIANFLVNAPSPQTLNNGNAITGW"
     gene            complement(2903..3049)
                     /locus_tag="PC466_003662"
     CDS             complement(2903..3049)
                     /locus_tag="PC466_003662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exosporium protein"
                     /protein_id="HDF2771009.1"
                     /translation="MRKIILYLNDDTFISKKYPDKNFSNLDYCLIGSKCSNSFVKEKL
                     ITFF"
BASE COUNT         1264 a          477 c          464 g         1265 t
ORIGIN      
        1 tttatataat attttttcac taaatttttt tctttttaca acaaatactc actacctttt
       61 gatataatat ttttatcaat tattattata ttcaagtttt gaaaggagta ttaaaatgag
      121 tttattagtt ttcggacata aaaatccaga tacagattca atatgttctg caatttcatt
      181 agcacattta aagaacaaac taggaataaa agcaacagct tatgctttag gagatatcag
      241 aaaagaagct aaatatgcct tggattactt taaggtagat gcacctgaaa ttttagataa
      301 tgttagaata caagttagag atttaaatta tgataaagta gtacctttaa caccaacttc
      361 atctatatta gaggcttata accttatgga tgaaaaaaat gttaaaacac tacctgtaac
      421 ttatgatgat ggaacttttg ctggtatcat tactatgaaa gaaatagcta aaaatctact
      481 tcatcaacac tttacaacta tacacacatc actatcaaac atttgtaaaa accttaatgg
      541 tactattctt gtggactgtg gtgaagatat aaaaggtaga gtagtcactt tatcatttgg
      601 aatggagact ctaatagaga ctttaaaaga aggagacata gctattgttg gagatagata
      661 tgatagtatt gaatatgcta ttgatacaaa agttaaactt ttaatactta ctaatcatac
      721 agagatttca aaagatttgc tagctcttgc taagataaat ggagtgtctg ttgtttctgt
      781 tgaaagtgac aattataaaa cttctaatgt aataaatcaa tgtagtttct tagactctat
      841 agaagctaca gaaaatttaa ttacattcaa agaagatgat tatatggatg aaataaaaga
      901 gattatgcta gaaacaaact tcagatctta tccaatatta gatgatgata ataagttttt
      961 aggtttagtt tcaaaaggtc atctattaaa cccatctaaa aagaatgttg ttttagttga
     1021 ccataacgaa tatgctcaaa gtgctgatgg aattgaacaa gcaaacatag ttgaaataat
     1081 tgaccatcat aaacttggtg gtatttctac tgatgttcct atgtcattta gagttatgcc
     1141 tgttggatgc aatagtacta taatttatca aatgtacaaa gaaaacaatg ttgagatacc
     1201 ttatgaaata gctgggcttc ttttatctgc tatattatca gatacattat tatttaagtc
     1261 tccaacaaca actgatatgg ataagaaagc ttgtgaagaa ttaagtaaaa tagcaaaagt
     1321 agacatggaa aaatacgcta tggatatgtt taaatgcggt acttctttag atgaatatac
     1381 tatagaagaa atagtaaata tggattttaa agaatttaat atgagtggac atagagttgg
     1441 tattggacaa gtatttacct tagacataga ctctatattt gctaaaaaag atgagttttt
     1501 atcttatata aattcgactg attatgacaa actaattctt gcggttacag atataatcaa
     1561 agaaggttct tatttaatct ataaagcaga agatagctta attgctaacg catttgatgt
     1621 tgaaggtgtt caaggtacat ttgcaccagg tgttgtatca agaaaaaaac aattagtccc
     1681 taatttaact actgcaatca aaaattttaa ataatataaa atttttaaat aacgaaaact
     1741 gtctcaaatc tatatttgag acagtttttt attatacata tattgataat aaagttaaat
     1801 aaaaatccat aaatttaaaa tttttatgaa tatattttat tattattgtt attttattca
     1861 ttctaaaata ggtaaaactc aatatataaa aatacttttg tcatttaaat aaaacctaaa
     1921 tagtttttaa gattatttta gacacgtttt aagtcataac agtatcagct attctaaata
     1981 tcgtcaaagt agccgcagtt cctgctgatt gcccatttcg tatccctact gttgtagatg
     2041 aaaaattatt tattgtaaaa gtagtccccc caaataaaaa accagcaaaa tatccagaaa
     2101 gtactcctcc gcctcctggc tcagtagtaa gccctgccaa atcttttcct cctaaaattg
     2161 ggaataggat agcaaaagaa tattgattta tacttgatga acctggttgt aatgctactg
     2221 aaactgatat ataatacaca ccattttctt gtactgtaaa cgtaccattt gcatctactg
     2281 ttatacttga actatttcct attattgttt accaacctgt tatagcattt ccattattta
     2341 gtgtttgtgg agatggtgca tttacgagga agttagcaat tggctgagag gaattgcctg
     2401 ttgctcctgt tggacctgtt gctcccattg gtcctatact tcctgtcgct cctcttggtc
     2461 ccattggacc tgtaattcta attggaagac actcacattt aggataacaa ttatctataa
     2521 ttctatcttc aaatgttaca agtatatacg gtttgttaca atccctacta gatgtaaatt
     2581 caaaaatctg ataagggtaa tttaaagata aagctaaccc ataattagga tatttattca
     2641 ttgcccatgc ttttatagtt cccgtaatat ttaaacaaat atagttggat gtatcactta
     2701 tcccaattgg taaatatccc ctgatatttt ccatagacac tctatcattc catgttatag
     2761 ttcgtaaatt ataatattca cttattcttt taatttcaat atctactttt tctttaaaaa
     2821 tatgattctt atttgaatca atatgaataa ataactctgc ttttaatata cttttgtctt
     2881 ttaatatatc tggtattctc acttaaaaaa aagtaatcaa cttttctttt acaaaactat
     2941 ttgaacattt acttcctatt aagcaataat ctaaattact aaagttttta tctggatatt
     3001 ttttagatat aaaagtatca tcatttaaat aaagtataat ttttctcatt tataatccct
     3061 ccattttggg tctatatcat actatgttta aaatacatgc ttagttacaa tacaattaaa
     3121 atttatagta ttaaattttt atataataat gctgatttct acaaaaaaag aacatgtcat
     3181 tagaaacttc taatagcatg ttctttttca ttattatata ttacacttta aattattcct
     3241 tgactggctt agctggtgta aactaaacca gtctttctaa aatattaagc acttttttct
     3301 tattatgttt tttaggattt attgtctcta ttattgtaaa ccaaagttat aaaattgtaa
     3361 atagaatata ttaccataac aatatttttt tataagtaaa aattataaaa aaccttattt
     3421 ttattaaata gaataaataa aataagttta aaaaatactg aaataagtgt
//
LOCUS       DAMJYN010000183         3266 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.189, whole genome shotgun sequence.
ACCESSION   DAMJYN010000183 DAMJYN010000000
VERSION     DAMJYN010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3266)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3266)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3266
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.189"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            38..649
                     /locus_tag="PC466_003663"
     CDS             38..649
                     /locus_tag="PC466_003663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA pyrophosphatase"
                     /protein_id="HDF2771010.1"
                     /translation="MINDIKNKFKNYKPYINGYKNMKRASVLIPIIEINNTHYILFEV
                     RSKNLKHQPSEISFPGGKIESGETPYEAVIRETCEELGTFSDNIEVISSLDLLITPVK
                     FIIHPYLGYIKNINNLNINKDEVDHTFLVPIKYLLENPPNTYSNTVKVFPDENLPYGS
                     IPNQKDYKFESGSYPILFYKYKDYVIWGMTAKILENFLNFLSE"
     gene            947..1285
                     /locus_tag="PC466_003664"
     CDS             947..1285
                     /locus_tag="PC466_003664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3784 domain-containing protein"
                     /protein_id="HDF2771011.1"
                     /translation="MFAVGFVVIIALAFFILSVLLFNGKASMLLAGYNSMSKKEKARY
                     DKKKLCRSSSIVTFIVSIMLFIMAFLGYRIESGQMDEKKMVPFSIIFIIVILSSVFFN
                     ILYSNKKCKK"
     gene            complement(1692..3128)
                     /gene="miaB"
                     /locus_tag="PC466_003665"
     CDS             complement(1692..3128)
                     /gene="miaB"
                     /locus_tag="PC466_003665"
                     /EC_number="2.8.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (N6-isopentenyl
                     adenosine(37)-C2)-methylthiotransferase MiaB"
                     /protein_id="HDF2771012.1"
                     /translation="MSKRKQVTIPIEKIQEQDKYIEQIHRQNEEYFNRTGKRKLVFTQ
                     TFGCQMNEHDSEKLCSMLEEMGYQMSMMVEESDLIIYNTCAVRENAELKVYGNLGQLK
                     HLKGKNPDMKIAVCGCMMQQPHVVEELRKKYKHVDLIFGTHNLYKFPQLLTESINSDK
                     MLVDVWDVDGEVIEGLRSNRKFELKAFVNIMYGCNNFCTYCIVPYTRGRERSRTPEDI
                     INEIKELVANGTKEITLLGQNVDSYGKTLENPVSFSELLRKVNDIEGIERVRFMTSHP
                     KDISDEVIYAIRDCDKVCEFLHLPIQCGSSSLLKKMNRHYTKEYYLEIIEKAKKEVPG
                     IAFSTDLMIGFPGETEEDLLDTLDVVEKVRYDSAFTFIYSKRQGTPAAKMENQIPEDI
                     KHDRFNRVLEAVNRISAEINDGYKDRIVEVLVEGRSKNNENKFAGRTRQNKLVNFEGG
                     NDDLIGKLVMVKITEPRTFSLNGILVNN"
BASE COUNT         1127 a          478 c          369 g         1292 t
ORIGIN      
        1 tatataattt ttaataatat tattttagga ggtaaaaatg ataaacgata ttaaaaataa
       61 attcaaaaat tacaaaccat atataaatgg atacaagaat atgaagagag catctgtttt
      121 aattccaata atagaaataa ataacacaca ctatatatta tttgaagttc gctcaaaaaa
      181 tttgaagcat caacctagcg aaatttcttt tccaggtggt aaaatagaat caggtgagac
      241 tccatatgaa gctgttatta gagaaacttg tgaggaactt ggaactttta gtgacaatat
      301 agaagtaata tcaagtcttg acctccttat aacaccagta aagtttatca tacatccata
      361 cttaggatat ataaaaaata ttaataattt aaatataaac aaggatgaag ttgaccatac
      421 ttttttggtt cctataaaat atcttttaga gaatcctcca aatacttata gtaatactgt
      481 aaaagttttt ccagatgaaa atctaccata tggttcaatt ccaaaccaaa aagattataa
      541 atttgaaagt ggaagttatc ctattctgtt ttataaatat aaagattatg taatttgggg
      601 aatgacagca aaaatactag aaaacttttt aaatttttta tcagaataac actcataata
      661 aatcatcaaa acttttacat aagaaattta taaaagtttc taaatttaac aattctaaaa
      721 tatcaataac tatattttgt agcacttttt tattttatta ttgtttgaat atttgatggt
      781 tttcaatgca atttcaacat aaatactatg tattagtgta tactgttgat gaattaaagt
      841 atgataatct atttaataaa gtatgaagta aatgatttta atgtgtcttt atggtaaaat
      901 tactaataag taataaaatt aattaaaata tatggaggtg cttataatgt ttgctgtagg
      961 atttgttgtt ataattgcac ttgccttttt cattttaagt gtactattat ttaatggaaa
     1021 agccagtatg ctactagcag gttataactc tatgagtaag aaagaaaaag cacgatacga
     1081 taaaaaaaaa ttatgtagaa gttctagcat tgttactttt attgtctcta taatgctatt
     1141 tattatggca tttttgggat atagaataga gagtggtcaa atggacgaaa aaaaaatggt
     1201 tcccttttct ataatattta taatagtcat actttccagt gtatttttta atatcctcta
     1261 ctctaacaaa aaatgtaaaa aataaatagt tgtaagttga gcagttaatt ataaaagatt
     1321 gactgctttt tcatgtatat tgactactct tattaaatat tttaacattt aaaaatctat
     1381 gtaaaaataa tgaatatagt acaaacttct aataatgatt ttacctttgt ggttacagtc
     1441 cactatatat aatttaatat gataacatgg aattactaat gacaactaag taagctttta
     1501 taaaatataa taaaacaaaa atagatgtac aatgaaatta tatcttatat caaatttatt
     1561 tttattaata gcaaaaactt acattagcat aacatatgac aaattcgctt aaaataaaaa
     1621 tttttaatat aatttgttct atagtacatc tatttcgatt agtttacata attttattat
     1681 tttgtacaat attaattatt tactaatatc ccatttaatg aaaaagttct aggttcagta
     1741 attttgacca taactaattt accaattaaa tcatcatttc caccttcgaa atttacgagt
     1801 ttattttgtc tagttctacc agcaaactta ttttcattat ttttacttct tccttcaact
     1861 agaacttcaa ctattctatc tttatatcca tcatttattt ctgcagaaat cctatttaca
     1921 gcttctaaca ccctattaaa tctatcatgc tttatatctt ctggtatttg attttccatt
     1981 ttagcagcag gagttccctg tcttttagaa taaataaatg taaaagctga atcatatcta
     2041 actttttcaa ccacatctaa agtgtccaat aaatcttctt ctgtttctcc tgggaaacca
     2101 atcattaagt ctgtagaaaa agcaatacct ggaacttcct ttttagcttt ttctattatt
     2161 tctaaataat attcctttgt ataatgtcta ttcatttttt tcaaaaggct actgcttcca
     2221 cattgtattg gtagatgtaa aaactcacac accttatcac aatctctaat tgcgtatatt
     2281 acttcatcag atatatcttt tggatgagat gtcataaatc gaaccctttc aattccttct
     2341 atatcattca cttttcttaa aagttctgag aatgaaactg gattttcaag tgtcttacca
     2401 taagaatcta cattttgtcc aagtaaagtg atttctttcg ttccatttgc aacaagctct
     2461 tttatctcgt taattatatc ttcaggagtt ctacttcttt ctcttcctct tgtgtatggg
     2521 actatacaat atgtgcagaa attattgcat ccatacatta tatttacaaa tgcttttaat
     2581 tcaaattttc tattacttct aagaccttct attacttctc catccacatc ccatacatcc
     2641 actaacattt tgtcagaatt tattgattct gtaagtaatt gcggaaattt atatagatta
     2701 tgtgttccaa atataaggtc tacatgttta tatttttttc ttaattcctc tacaacatgt
     2761 ggttgttgca tcatacatcc acatacagct attttcatat ctggattttt tccttttaga
     2821 tgttttaatt gtcctaagtt accatacact tttagctctg cattttctct aactgcacag
     2881 gtgttatata ttattaaatc actttcttca accatcattg acatttggta tcccatctct
     2941 tctaacatcg aacataattt ttctgaatca tgttcattca tttgacaccc aaaggtttga
     3001 gtaaacacga gttttctctt tccagttctg ttgaagtatt cttcattttg tctgtgtatt
     3061 tgttctatat atttatcttg ttcttgtatt ttctctatag gtattgttac ttgttttctt
     3121 ttgctcacgt ctattcctcc tagttaattt cttatattac acataacctt aattatatca
     3181 aataagaaaa atcttttaaa gatattatta tttttctagt tgtgttttaa tagtaaatct
     3241 aatgatttat atatactata tttcta
//
LOCUS       DAMJYN010000184         3208 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.190, whole genome shotgun sequence.
ACCESSION   DAMJYN010000184 DAMJYN010000000
VERSION     DAMJYN010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3208)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3208)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3208
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.190"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(145..666)
                     /locus_tag="PC466_003666"
     CDS             complement(145..666)
                     /locus_tag="PC466_003666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HDF2771013.1"
                     /translation="MATIDLIVLGIVKQQPKSAYDIQKAVEYRNISRWVKISTPSIYK
                     KVIQLEQKGYIESKTVKNGKMPEKAVYSLTELGETHFLDLMFDTSSKPINILLDFNAV
                     IVNLNSLTPEKQKLCLNNIEENVQELKKTIEENIIIKTEVPETAKAVLEQQLVLAQAL
                     ETWINSLKDNMGN"
     gene            794..2158
                     /locus_tag="PC466_003667"
     CDS             794..2158
                     /locus_tag="PC466_003667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF2771014.1"
                     /translation="MKESNKKIELLGSAPISKALLSMGLPTMIGMMITALYNLVDAYF
                     VGGLGTSQMGAISVAFPLGQLVVGLGLLFGNGAASYIARLLGHGDNEKAGKVVSTSIY
                     SSIIVGTLVIIVIMIFLNPILKLLGATKSIMPYAISYASIYVVSSIFNIFNVTMTNIV
                     TSEGAAKTTMCAMLLGALLNMILDPIFIYTFGLGVRGASIATAISQIASTLVYVGYIL
                     SKKSIFSFRINECCFSKEIFSEILKIGIPTLIFQLLTSLAITLTNMEATKYGDSVIAG
                     MGAVTRITSLGSLVVFGFIKGFQPIAGYNFGSKNYDKLHIAIKTSILWTTIFCVVLGL
                     ILVLFPKSIISQFTSGDILLIENGSKALRANGFSFMLFGFYTVYSTLFLALGKAKEGG
                     FLGMCRQGVCFIPIILIIPVFYGLNGILYAQPIADLMAAIIAGFMSIRLHKELNLLKI
                     NGMH"
     gene            2347..3024
                     /locus_tag="PC466_003668"
     CDS             2347..3024
                     /locus_tag="PC466_003668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HDF2771015.1"
                     /translation="MISQNEIDILTHSLPFWDKLTDLQKELLISSANTSDYKKGNPVH
                     CGDSDCIGILIIKSGTIRTYILSDEGREVTLFRLDDGDVCILSASCILKTITFDVYVD
                     AETDCDIIQINSSVFAKLSTENIHAELFSYKLATERFSDVMWAMQQILFMSFDKRLAS
                     FLIDEIAKNGSSTINMTHEQIAKYMGSAREVVSRMLKYFAREGIVSLSRGGIKVLDKD
                     KLRSLTL"
BASE COUNT         1008 a          447 c          504 g         1249 t
ORIGIN      
        1 aaaagtttaa cattctccct caattaagtg agctttattt taaatatact tttcagttta
       61 tatcatttgt ttcatttttt ctaatatctc attattaaat atgctggttt ttgtttaatg
      121 attattaagt tagcttctct aattctaatt ccccatatta tcttttaaag aatttatcca
      181 ggtttccaat gcttgtgcta gcaccaactg ttgctccaac actgcttttg ctgtctctgg
      241 tacttctgtc tttataatta tattttcctc aatagttttc tttaactctt gaacattctc
      301 ttcaatatta ttgagacata atttctgttt ttctggtgta aggctattta aatttactat
      361 aacagcatta aaatctaaaa gaatatttat tggtttgcta gatgtatcaa acattaaatc
      421 taaaaaatgt gtctcaccta attcagttaa tgaataaact gctttttctg gcatttttcc
      481 attcttcaca gttttacttt caatatatcc cttttgttct aattgaatta cttttttata
      541 aattgatggt gtacttattt taacccaacg tgatatattc ctgtattcca ctgccttttg
      601 aatatcataa gcactcttgg gttgttgctt tactattccc aatacaatta aatctattgt
      661 agccataaaa atcatctcct ttagttttct tactattgac aaatactata aattatagta
      721 ctattttcca tacttactat aatttatagt attataattt agacttaatg tcaatagaag
      781 aggagtgtta agtatgaaag aaagtaacaa aaaaattgaa ttattagggt ctgccccaat
      841 ctcaaaagca ttgttatcta tgggattacc taccatgata ggtatgatga taactgcatt
      901 atacaatttg gttgatgcat actttgtggg tggacttgga acaagtcaaa tgggagctat
      961 atccgttgca tttccattag gtcagcttgt tgtgggatta ggattattgt ttggaaatgg
     1021 agctgcttca tatattgcca gacttttagg ccatggtgat aatgaaaaag caggaaaagt
     1081 ggtaagtaca tctatttaca gtagtattat agtgggtaca ttagttatta ttgtgattat
     1141 gatttttctc aatccaattt taaaattgtt aggagctaca aaaagtatta tgccttatgc
     1201 aatatcttat gctagcattt atgtcgtgtc atctattttt aatatattca atgtcactat
     1261 gactaatatt gtcacaagtg aaggagctgc taaaacaact atgtgtgcta tgttattagg
     1321 tgctttgctt aatatgattt tagacccgat attcatttat acttttggtc tgggggtaag
     1381 gggtgcttct attgcaacag ctatctcaca gattgcttca acacttgttt atgtaggata
     1441 tattttaagc aagaaaagta tatttagttt tagaattaac gaatgctgtt tttcaaaaga
     1501 aattttttca gaaatcctaa aaattggcat acctacatta atatttcaat tattgactag
     1561 tcttgccatt acattaacta atatggaggc tacaaagtat ggtgattctg tgatagctgg
     1621 aatgggtgct gtaacacgaa taacatcttt aggtagtctt gttgtatttg gttttataaa
     1681 aggtttccaa ccaattgctg gttataattt tggttcgaag aactacgata aattacatat
     1741 agcaataaaa acttccatat tatggactac aatattttgt gtagtgcttg gtcttatatt
     1801 ggtgcttttc ccaaaatcta taatttcaca atttacaagt ggtgacattc tattaataga
     1861 aaatggtagt aaagctctta gggcaaatgg gttttcattt atgctatttg gattctatac
     1921 agtgtattct acattattcc tagcactagg aaaagcaaag gaaggtggat ttttaggtat
     1981 gtgtagacaa ggcgtctgtt ttatccctat aattttgatt attcctgtat tctatgggtt
     2041 aaatggtatc ttatatgcac aaccaatagc tgatttgatg gctgctataa ttgctggttt
     2101 tatgtctata aggttacata aggaacttaa tcttttaaaa ataaacggta tgcattagtt
     2161 atacaaacct actatcatca aaacatatta ctttctcatt aatagcaaga atatatatta
     2221 tcatattttt tctacataaa tcatactatt actatctgac taaataatcc tcttaacaaa
     2281 ctacttgtca atttatctat tcacttgtat catgggatta taacaattta agaaaggaga
     2341 tattgtatga tttcacaaaa tgaaattgat atacttacac atagcttgcc tttttgggat
     2401 aaacttactg acttacaaaa agaattatta atttcttcag caaatacctc ggattacaaa
     2461 aaagggaatc cagtacattg tggtgatagt gactgtattg gtattttgat tataaagtct
     2521 ggaacaatac gtacatacat actttcagat gaaggtcgag aggttacact gttccgactt
     2581 gatgatggag atgtatgtat tttatcagct tcctgtattc taaaaacaat aacttttgat
     2641 gtctatgtag atgctgaaac ggactgcgat attatacaga ttaattcctc tgtttttgca
     2701 aaattatcta cagaaaatat tcatgcagag ttattttcat ataaattagc taccgaacgt
     2761 ttttctgatg ttatgtgggc tatgcaacaa attcttttta tgagttttga taagcgtttg
     2821 gcatcttttt taattgatga gatagctaaa aatggcagta gcactataaa tatgactcat
     2881 gagcaaattg ctaagtatat gggtagtgcc agagaagttg tatcgagaat gttgaaatat
     2941 tttgctagag aaggtattgt gtctttatct cgtggtggta taaaagtatt ggataaggat
     3001 aaacttcgtt ctttgacact gtaaaagtgt gtctcaaaat gaacttttta gttcatgagg
     3061 cactcttttt tgtgtgaaat caaatatatt ttcataattt caataataaa aaagatactt
     3121 atatctattt ttatatagta tcttatttga tatttacatt tattttttat gtatattttt
     3181 atattttaat aatttagttt aactattt
//
LOCUS       DAMJYN010000185         3182 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.191, whole genome shotgun sequence.
ACCESSION   DAMJYN010000185 DAMJYN010000000
VERSION     DAMJYN010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3182)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3182)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3182
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.191"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            657..1673
                     /locus_tag="PC466_003669"
     CDS             657..1673
                     /locus_tag="PC466_003669"
                     /inference="COORDINATES: protein
                     motif:HMM:NF012780.1,HMM:NF013741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HDF2771016.1"
                     /translation="MGTLFSLITFILLLVLTAFFVATEFAIVKVRETRIAQLFNAGEK
                     KAISAKKVVDHLDEYLAACQLGITITALGIGMVGESTFEFILNPLFSSIGIPEAWIHP
                     FTIGGAFVIATFLHVVVGEMAPKTIAIQKAEYITLLFAKPIIFFYKIMYPFIWLLNGA
                     ARLILKMFNMKPAKESEVFHSKEELKQLIQDSHEGGEINDSELHHINQAFKFDNLVAK
                     DIMIDPEHVKTLNLNTRFDDAIQQIKVDAFTRYPAIKDDQIVGFIHSKSLFNVDQPSK
                     LATFVNPIINVKLNTPLKHILEIMKKKKVHITAVYDNADFKGIITLENILEEIVGDIE
                     DEYN"
     gene            1879..2164
                     /locus_tag="PC466_003670"
                     /pseudo
     CDS             1879..2164
                     /locus_tag="PC466_003670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005209730.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
     gene            2591..>3182
                     /locus_tag="PC466_003671"
     CDS             2591..>3182
                     /locus_tag="PC466_003671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017465246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HDF2771017.1"
                     /translation="MVQTIITAAILYIATAVDLLVILLIFFARAKTRKEYRDIYIGQY
                     LGSIILILVSLFLAFVLNYVPEKWILGLLGLIPIYLGIKVAIYDDCEGEKRAKKELNE
                     KGLSKLVGTVSLVTIASCGADNIGLFVPYFVALDIIELLTTLIVFLVLIFFLVFTAQK
                     LARIPGVGEIVEKFSRWIMAVIYIALGLFIIIENETI"
BASE COUNT         1094 a          416 c          549 g         1123 t
ORIGIN      
        1 cgggattttg ggattgtgct tgtacaatcc ttctgcttct tcgaatttgc aaatcccatt
       61 cctttcccgg taaaaaatta tcgtgggatg ttctttagca atttcaatat aagcttcgtg
      121 tagttatgaa aataattacg acaatggccg tttcattaga taagtgttat tgaaattgat
      181 aaagagaatt ctaaaattgg ttagataaaa taaatgaaag aataacagaa tagtcattgt
      241 ttattcaata gttatatata tagtttgcgg caaaaataaa gacgaagtgc tgaggagcac
      301 ttcgtcgagt ggatggttat taaatagttg tttattaaaa gcgttatcca atttgaggat
      361 gatgtaaaat taatttttat gatattcatc tatccttata tcaatacgat tgataatcgt
      421 tagatacagt gatttcaatt gctatttctc taattcttca atatctttga acattgtctg
      481 taacacatta gcagtcatat cagtattata atgtgggaat tcagcttgtt tgtcttgttc
      541 tagtagatag cactatttat attagtattt aaaatttaaa tattttgatt atataaaaaa
      601 cgttgataca attcatataa tagtaagtct atatttttta ttttggagga acatatttgg
      661 ggaccctatt tagtctgatt acttttatat tattattagt cctaacggca tttttcgtag
      721 cgacagagtt tgctatcgtg aaagtcagag aaacaagaat tgcacaattg tttaatgcag
      781 gagagaagaa agcaatctct gctaaaaaag ttgtcgatca tcttgacgaa tacttagctg
      841 cctgtcaatt aggtattacc attaccgctt taggtattgg tatggtcggg gaatccacat
      901 ttgaatttat tctaaaccca ctattcagta gtataggtat tcctgaagca tggatacatc
      961 catttactat tggtggtgcg tttgttatcg cgacattttt acatgtagtt gtaggtgaga
     1021 tggcgcctaa gaccattgcg attcaaaaag ctgagtatat tacattactc tttgcgaagc
     1081 caatcatctt tttctataaa ataatgtatc catttatttg gctattaaat ggtgcagcac
     1141 gattaatctt gaaaatgttc aacatgaaac cagctaaaga gagtgaggta ttccactcta
     1201 aagaagaatt gaaacaatta attcaagata gccatgaagg tggcgaaatt aatgacagtg
     1261 agttacacca tattaatcaa gcatttaaat tcgataattt agtcgcaaaa gatattatga
     1321 tcgatccaga acatgtcaaa acactcaatt taaatacgcg ttttgatgat gcgattcaac
     1381 aaattaaagt agatgcattt acaagatatc cagctattaa agatgatcaa attgttggtt
     1441 ttatccattc caaatcatta tttaatgtgg atcagccatc taagttagcg acatttgtta
     1501 atccaattat caacgttaaa ctgaatacgc cattgaagca cattttggaa ataatgaaaa
     1561 agaaaaaagt tcatattact gcagtttatg ataatgctga tttcaaaggt atcattactt
     1621 tagaaaatat tcttgaagaa atcgttggcg atattgaaga tgaatataat taatacaact
     1681 gtttatactg accctatcat tgagatttga aagtctgaat gatagggcat tttttattta
     1741 ccgactttaa actttgacat ccgactcaat ttgtaactat aacgattaca tgaaatgaga
     1801 agattgaaaa ttagtagtcg ttttactgta gttggcgaac aagtatcatt gattaaacga
     1861 atcatttaag actagacgat tcattgttat ggacatattc atgatgacta tcgtattgaa
     1921 tatttacgta aacatattca agctgctatc gaagcagtag ataaagatgg cgtagactta
     1981 ataagttata caccttgggg tattattgat atcgtatcat ttacaactgg cgaaatgaaa
     2041 aaaacgctat ggattaattc atttagattg taacaatgag ggaaatggct cattagaacg
     2101 taccaaaaaa gcttcatttg attggtatcg taaagttatt gaatcaaatg gtgaagaatt
     2161 ataattgtgt tacatcaata actaaataga aaagacacct tgttatagct ttaataatga
     2221 tagagatggc gtaatagaaa cattgaatac attacttata aatgacgata attcataatg
     2281 aatgaaagaa tatgtaatct aactttatac gattaaccgc attattaact gatacgtaga
     2341 agcgtatcat aaatgatgcg gtttttataa gattcttctt attagtgaaa ttgttaaaaa
     2401 acaaaatgca atgaactgac aaattaaaat cgctttaagt cgtattctca aagaatctat
     2461 aaatcactcg tatgtacata gctccttact atcagttaaa gtgtcacttt tcggttataa
     2521 tatttattat tcataagata tgcaatatat gatacaattc attcaaatgt atatttgaat
     2581 gaggtgctct atggttcaga ctattataac tgcggcaata ctttatattg caactgcggt
     2641 agatttatta gtgattttat taatattttt tgctagagca aagactagaa aagaatatag
     2701 ggatatttat ataggtcaat atttaggatc gattatcctc atattagtca gtttattttt
     2761 agcttttgtg ttaaattatg ttccagagaa atggatatta ggtttattag gtttaatccc
     2821 catctactta ggtataaaag ttgctattta tgatgattgt gaaggtgaaa aaagagcaaa
     2881 aaaagaatta aacgaaaaag gtttgtccaa attagtaggg actgtttctt tagtgacaat
     2941 tgcaagttgt ggtgcagata atattggttt atttgtccct tattttgtag cattggatat
     3001 tattgaatta ctgactacct taattgtatt tttagtttta attttctttt tagtattcac
     3061 agcacaaaaa ctagctagaa ttcctggtgt gggtgaaatt gttgagaaat tcagtcgttg
     3121 gattatggct gttatttaca tagcattggg cttatttatt attattgaaa atgaaaccat
     3181 ac
//
LOCUS       DAMJYN010000186         3167 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.192, whole genome shotgun sequence.
ACCESSION   DAMJYN010000186 DAMJYN010000000
VERSION     DAMJYN010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3167)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3167)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3167
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.192"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(258..515)
                     /locus_tag="PC466_003672"
     CDS             complement(258..515)
                     /locus_tag="PC466_003672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDF2771018.1"
                     /translation="MKIKVEDIPVQFHAMVEIIGIDKFIEVAKLYGGTNTYIPTYKGL
                     FRYARNRDIVKQFNGVNHNELAIRYNMCVSNIKRILNENNV"
     gene            1095..1316
                     /locus_tag="PC466_003673"
     CDS             1095..1316
                     /locus_tag="PC466_003673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1659 domain-containing protein"
                     /protein_id="HDF2771019.1"
                     /translation="MEVVSTKNLSSIKLKLDAGFDDKGKAVVKSKSFANVKAEALNED
                     VYAVAEAIASLQENPIVDILKLDSTSLSK"
     gene            2008..2238
                     /locus_tag="PC466_003674"
     CDS             2008..2238
                     /locus_tag="PC466_003674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2922 domain-containing protein"
                     /protein_id="HDF2771020.1"
                     /translation="MEIKKKLVMSFKNVKDKQVSFSIENPKDDLTEENIKSVMDLIVS
                     KNIFSVGGFDLASVVEAKVVETNTTPYDLVIE"
     gene            2251..2400
                     /locus_tag="PC466_003675"
     CDS             2251..2400
                     /locus_tag="PC466_003675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvrJ family protein"
                     /protein_id="HDF2771021.1"
                     /translation="MDDSLQLLITNVGFPIALSMYLLVRIEGKLNTLSNSIDTLSKNI
                     LIFKK"
     gene            2657..3094
                     /locus_tag="PC466_003676"
     CDS             2657..3094
                     /locus_tag="PC466_003676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family transcriptional regulator
                     DNA-binding domain-containing protein"
                     /protein_id="HDF2771022.1"
                     /translation="MKIHVEQGINCDDIEITIKCSALDNNIEKIISLLSTPLLDIKGK
                     KSGEIYKLNVCDILYFETVGNKTFAYYEDDVFEIDLKIYKLSKLLANTSFSRISKSMI
                     LNMDYIKSIKVISHNRMQATLKNNEKVIINRRYIKNIKEKLNI"
BASE COUNT         1278 a          401 c          337 g         1151 t
ORIGIN      
        1 atttatatag tttatttatt tatttttccc ctttatacaa gcaattgtat cattttatct
       61 attttttagc caacaaatat tttcgaccat tttctttgta ttctcaatat atctccagta
      121 tttaacaaat ttttttatag aatatacaat gtatttaaat taataagtag taaatttagt
      181 taatttgtct aaaaaaactt tataaaacat cttctttgtc tttactctta catttaacaa
      241 ggctattttc attatgttta aacattattt tcattgagta ttcgcttaat attgcttaca
      301 cacatattat atctaatagc caattcatta tggttgactc cattaaattg ttttactata
      361 tccctatttc tagcatatct aaaaagcccc ttatacgtag gtatataagt atttgttcct
      421 ccatacaact tggcaacctc tatgaactta tcaattccga ttatttctac cattgcatga
      481 aattgaactg gtatatcctc cacttttatc ttcataagtt acacctcctt taagatattt
      541 ttatagactt aacaaagttt ttatttaata cattattgac taaactatat ttattagttt
      601 tattgaatct aataaaaaat ttcttagctt taaaattaat ttttgtatta actttaataa
      661 aatttctcat aacttataac tttgttagct ttaataaaga ttttaatggt ttaaaagtaa
      721 aatgttaata ttggactttt aactttttta tttacagatt aaatttaata aaatttttaa
      781 cataagcttt aacatttaat ttaacataaa ctttggtacc taacatttaa ctctacacat
      841 atgaaaatcc atacaaaact atctcaacta agcatgaata tatacaaata ctatttcaaa
      901 acactaagaa catatcttca aaaataactt gtaaactttt tcatcatcag aaaagtaaaa
      961 tttttcctat aaaaatttac acaaaaaatc tttagaaatt actgtttaac tccgatatta
     1021 tcttagatga tagtattata gctaacaaag aaagtcgaca aatctttgaa attaaatttt
     1081 taggaggtaa ttttatggaa gttgtttcaa caaaaaattt atctagtata aaactaaaat
     1141 tggatgctgg ttttgatgat aagggtaagg cagttgttaa aagtaaatca tttgcaaatg
     1201 taaaagcaga ggcattaaat gaagatgttt atgctgttgc agaagcaata gcaagtcttc
     1261 aagagaaccc tattgtagat attttaaaat tagatagtac atcattatct aaatagtatc
     1321 ttttaaacgt actctgcttt acaaattaaa aaaattaact ctttatataa aagattaagt
     1381 tatataacgc acttaatacg ctatagattt ggcagattat aacttcaatt ttggttataa
     1441 ctttaatata ttaatgcttt gaaaaattaa tatattaaac gtatttcaac ttaaacatgt
     1501 tagctatttt aaatgctacc ctactttaat ctaattaatt gaaataaatt aaatattttc
     1561 tatatcagca ataactagag tcaacaatta aaatactaat attgacaatt gaaacactga
     1621 tactaacaaa caaaacacta atattgacaa ttgaaacact gatactaaca aacaaaacac
     1681 taatattgac aattgaaata ctaatactaa caagcaaaac actaatattg acaattgaaa
     1741 tactaatact aacaagcaaa acactaatat tgacaattga aatattaata ctaacaagca
     1801 aaacactaat attgacaatt gaaatattaa tactaacaag caaaacacta atattgacaa
     1861 ttgaaatact aatactaaca agtaaaacat taatattgac aattgaaata ttaatactaa
     1921 caagcaaaac actaatattg acaattaaaa taccaatatt aacaagcaaa caattaaaat
     1981 ataaattatt atatcggagg taattatatg gaaattaaga aaaaattagt catgagcttt
     2041 aaaaatgtaa aggataaaca agtttctttt tctatagaaa atccaaagga tgatttaact
     2101 gaagaaaata taaaatctgt catggatttg atagtatcta aaaatatttt ttcggttgga
     2161 ggatttgacc tagcttctgt tgttgaagcc aaggttgtgg aaacaaatac cactccttat
     2221 gacttagtta tagaataggg ggctaatttt atggatgata gtttacaact gttaataacc
     2281 aatgttggtt ttcctatagc tctatccatg tacttgttgg ttagaattga gggtaaatta
     2341 aatactttat caaacagtat tgatacatta tccaaaaata ttttgatatt taagaagtaa
     2401 tttgacaata tatgtaagtc ataaaatagg tctatttgta aaataattag acatattcta
     2461 tgctaaatac taggatattt ggataattta tccaaatatc catagtattt ttttgaattt
     2521 taccacctca aatttgaatt tcactatttt atttttgaat ttcactatgc ttaatttgaa
     2581 atttagaacg catctagttg gactcaataa gatataatgc tattctaatg acagtaataa
     2641 aatgaggtga tgattaatga aaatacatgt cgaacaaggt attaattgtg atgatattga
     2701 aataaccata aaatgttctg ctctagataa taacattgaa aaaataattt cattattgag
     2761 tacaccatta cttgatataa aaggtaaaaa atcaggagag atttataaac tcaatgtctg
     2821 tgatatttta tactttgaaa cagttggaaa taaaacattt gcttattatg aagatgatgt
     2881 atttgaaatt gatttaaaaa tatataaatt atcaaaatta ttagctaata catccttctc
     2941 acgaatatct aaatccatga ttttaaatat ggactacata aaaagtataa aagtaatatc
     3001 acataatcgc atgcaagcta ctttaaaaaa caacgaaaaa gttattataa atcgtcgtta
     3061 tataaaaaat attaaagaaa agctaaacat ttaataaaaa tctaaagtaa tttattaata
     3121 tcactaattg caaatttatt gacctattta ataattaata ataatat
//
LOCUS       DAMJYN010000187         3109 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.193, whole genome shotgun sequence.
ACCESSION   DAMJYN010000187 DAMJYN010000000
VERSION     DAMJYN010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3109)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3109)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3109
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.193"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            183..977
                     /locus_tag="PC466_003677"
     CDS             183..977
                     /locus_tag="PC466_003677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2771023.1"
                     /translation="MIEVDKLCKSFTRVVKDDKNKSSIRKLKKVKTKKEEFFAVNNVS
                     FKVMEGEIVGILGPNGAGKTTLLRMLGGILTPTSGSINISGYDYSIDRNSAKKEIGYL
                     SGNTKLYGRLSPRELLTTFASLYEMSKEDIEESIENIVKIMDMSEFIDNRIENLSTGQ
                     TQRTSIARCLIHSPKVYIFDEPTLGLDVLSSASIIDFMKNEKLRGKTVLYSTHYMEEA
                     ETLCDKIFMIHNGKIIASGTPQSLKEESGVNNLRDVFIKLARKEDI"
     gene            978..3038
                     /locus_tag="PC466_003678"
     CDS             978..3038
                     /locus_tag="PC466_003678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDF2771024.1"
                     /translation="MRSKIVKYIFKKEMLDILRDKKTLFMMIVVPLLLYPLLMLLMIQ
                     VMNMSASSMNSKDINIAFNNKPNKVLVSMIEDDNLEKDTKNTSNDKGKIRVLDVDNYK
                     KSLEENKIDAYIKMEEKKSSINYQIYINSSQENSSNALKRIETVLDKYKRFTIEKTLS
                     EKGLDVQATLEPITYSTVDVAKTEEVAGYFLGQILPFILIIGVLLGSIYPAIDVMAGE
                     KERGTLETLFTLPISNLELVMGKYMAVSLSAIVTAILNILSMGLTMAFILVSGGISSQ
                     FGFGNFNYGDLVLPIITTLICICLFSMVVSAISMCVCSLAKSFKDAQNYITPLMLIIM
                     IPSYVSMIPNIVLDRVTAVIPVVNISLLIKSVLSFKSDLNLIALVLASNVAFVILAII
                     LLSKMFNSEEILFGNSKSFSFLEKRSNIKKGSIPTVSDGVILYAVGLVLLIYVGSLVQ
                     IKFGMAGIIMTQFMIISLPLLFACYIKADFKEVFSLTVPKLKHVFGSIVLWIGGYILI
                     MIITQLILFLFPQNMEVAESLNKALFIKDSVLLNLLAIALLPAICEELFFRGFIFSSF
                     SKSKDKNKSIKLAIICSGVLFGIMHMDFIRIIPTSILGIIFAYSVYKSGSIFVSMLLH
                     FLNNSVAVVLNHYTTGNITNLYKFVEVDFSNLNVLKFALILLISLILIMLGLRVLDRK
                     SLRN"
BASE COUNT         1198 a          321 c          507 g         1083 t
ORIGIN      
        1 tttataatgt aaaaaaatgt tacaaaagat attataaacg aataaaaaat aataatttgt
       61 cagataaact tgtaaatttt tatgaataat ccattctaaa acaaaaaact gtgtataaaa
      121 aaggtttata tgttatattt atataaatat aacatatgaa cgagaaagga gtggtttgat
      181 aaatgattga ggtagataaa ttgtgtaagt cttttacaag ggttgtaaaa gatgataaga
      241 ataaaagttc aataagaaag ctaaagaaag taaaaactaa aaaagaagaa ttttttgctg
      301 taaataatgt ttcatttaaa gttatggaag gtgaaattgt tggaatatta ggtccaaatg
      361 gtgcaggaaa gactacatta cttagaatgt taggtggcat attaacacca acatcaggaa
      421 gtataaatat ttctggatat gattattcaa tagatagaaa ttcagcaaaa aaagaaatag
      481 gttatctctc tggaaataca aaactatatg gaaggctttc tccgagagaa cttctaacaa
      541 cttttgcaag tctatatgag atgtcaaaag aagatataga agaatcaatt gaaaatattg
      601 taaaaataat ggatatgagt gaatttatag ataatagaat tgaaaatcta tcaactggtc
      661 agactcaaag aacatctata gcccgttgtt taatacattc tccaaaagta tatatttttg
      721 atgagccaac actaggtctg gatgttttaa gtagtgcatc tattatagat tttatgaaga
      781 atgaaaaact aagaggaaaa actgttcttt actcaactca ttatatggaa gaagcagaaa
      841 ctttatgtga caagattttt atgattcaca atgggaaaat aattgcatca ggaacaccac
      901 agagtttaaa agaggaatct ggagtaaata atttgagaga tgtattcata aaacttgcca
      961 gaaaggagga catttaaatg agaagtaaga ttgtaaaata catatttaaa aaagaaatgt
     1021 tagacatatt gagagataaa aagactttat ttatgatgat tgttgtgcca cttcttttat
     1081 atcctttact tatgttatta atgattcaag taatgaatat gtctgcaagt agtatgaata
     1141 gtaaggacat taatatagct tttaataata aacctaataa ggtgttagta tccatgattg
     1201 aagatgataa tttagaaaaa gatactaaaa atacttcaaa tgataaaggc aaaataagag
     1261 tgttagatgt agataactat aaaaagtcat tagaagaaaa taaaattgat gcttatataa
     1321 agatggaaga aaaaaaatca tctataaatt atcaaatata tataaattct tctcaagaaa
     1381 attcttctaa tgcactaaaa agaattgaaa ctgttttgga taaatataaa agatttacca
     1441 tagaaaaaac tttatctgaa aaaggattag atgtacaagc tactttagaa ccaataacat
     1501 atagcactgt agatgttgca aagacggaag aagtggcagg atacttttta ggtcagatac
     1561 ttccatttat attaataata ggagttttac taggttcaat atatccagca atagatgtta
     1621 tggctggaga aaaggaaaga ggtacattag aaacattatt tacactccca atatcaaact
     1681 tagaactggt tatgggaaaa tatatggcag tttctcttag tgcaatagta acagcaattt
     1741 taaacatttt atctatggga ctgactatgg catttatttt agttagtgga ggtattagta
     1801 gccaatttgg ctttggaaac tttaattatg gagacttagt cttaccaatt ataactactt
     1861 taatttgcat atgtcttttt tcaatggtag tttcagcaat aagtatgtgt gtatgttcat
     1921 tagcaaaaag ttttaaagat gctcaaaact acataacacc tcttatgtta attattatga
     1981 taccatcata tgtttctatg ataccaaata tagtattgga tagagtgaca gctgtaatac
     2041 ctgtagtaaa tatatcttta cttataaaaa gtgtattatc ttttaaaagc gatttaaatt
     2101 taatagcctt agttttagca tcaaatgtag cctttgttat attggcaatc atactactgt
     2161 ctaagatgtt caattctgag gaaatacttt ttggtaatag taagagtttt tctttcttag
     2221 agaaaagaag taatataaaa aaagggtcta taccaactgt aagtgatggt gttattttat
     2281 atgcagtagg attagttcta ttgatttatg ttggttcttt agttcaaatt aaatttggta
     2341 tggcaggtat tataatgaca caattcatga taatttcttt accattatta tttgcatgct
     2401 atattaaagc tgattttaaa gaggtattta gcttgacagt tcctaaatta aagcatgtgt
     2461 ttgggagcat tgttctttgg attggtggat acatacttat tatgattata acacagctaa
     2521 ttttattctt atttcctcaa aatatggaag ttgctgaaag tttaaataag gctcttttta
     2581 tcaaagatag tgttttactg aatttactag caatagcttt attaccagct atatgtgaag
     2641 aactgttttt taggggattt atattttctt catttagtaa atcaaaagat aaaaataagt
     2701 ctatcaaact cgctataata tgtagtgggg tactatttgg tattatgcat atggatttta
     2761 ttagaataat tccaacatca atattaggta ttatatttgc atacagtgtg tataaatctg
     2821 gttcaatatt tgtatcaatg ttattgcatt ttttaaataa tagtgtagca gttgtgttaa
     2881 atcattatac aactggaaat ataaccaact tatataaatt tgttgaagtt gatttttcga
     2941 acttaaatgt acttaaattt gccttaattc ttctaataag tcttatatta attatgttag
     3001 gattaagagt tttagataga aagtctttaa gaaattaagt ataaagttat tatatagatt
     3061 aaaatattaa taagcactaa agtatatgga tatatcttgt atataaaaa
//
LOCUS       DAMJYN010000188         3012 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.194, whole genome shotgun sequence.
ACCESSION   DAMJYN010000188 DAMJYN010000000
VERSION     DAMJYN010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3012)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3012)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3012
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.194"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            82..2439
                     /locus_tag="PC466_003679"
     CDS             82..2439
                     /locus_tag="PC466_003679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HDF2771025.1"
                     /translation="MDKVNLERYSCDINVGLNKNQLQSRIDDNLINAFDNGKTKTYKQ
                     IFKDNIFTLFNLINIVLVCLLVSVGSFKNTLFIFIAVINTIIGVIQEIRAKRLLDNLS
                     VIVSNKVSVIREKEKKEIDVQELVLDDIMILKTGNQICADSKVLNGKLEVNESLVTGE
                     SDIIIKNKDDFLYSGSFVVSGEAFVRVENIGKDNYANKIVNDAKISKKHNSQLRNSLN
                     SILKIVGIIIIPLGIILFAKQHFGNGDSIATSVVGTVAAVNGMIPEGLTLLTSIALAV
                     GTIKLASHKTLVQELYCVETLARVDTLCLDKTGTITEGKMQVDDIVMLEEVDINEIMG
                     NICNSLKDDNATLNAIRDKYNVLDTYKAKNLIPFSSERKYSGVTFENKGTYLLGAFEF
                     IFKEKNKKIRIEVEKYSKKGNRVIVLAHSDSYMEDNNIPEDIKPLAFILILDKIRDEA
                     KETLEFFYNEGVDIKIISGDNPITVSEVARKAGLKTASNFIDATTLKNDNDIYEAVDK
                     YSVFGRVSPQQKKQMILALKKQNHTVAMTGDGVNDVLALKEADCSIAMASGSDVTKNV
                     SNLVLLDSNFASMPKVVMEGRKVINNIQRASSLFLVKTIFSFFLSLLTLFFFSRQYPF
                     VPIQLSLIGAVTVGIPSFFLALEANKSRISGNFLLNILKNALPGALCVTVNVIIVYNI
                     VEYLGYSSSVFSTMCAILTGVCGLLILRQQCLPFNKERLFLIVSMTIAFVIGILFLGG
                     LFSFVALSRELILITMALAILMPIMIKVMLFVLDEILETIVPDLN"
     gene            complement(2525..2842)
                     /locus_tag="PC466_003680"
     CDS             complement(2525..2842)
                     /locus_tag="PC466_003680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine/purine nucleoside phosphorylase"
                     /protein_id="HDF2771026.1"
                     /translation="MSEFKNVTAVKKANVYFDGKVSSRVIILPNGERKTLGLMLPGEY
                     TFSTREEEIMEMLAGSMDVKLPGSNEFVTYKEGQKFNVPSDSSFDLKVNEVVDYCCSY
                     IAD"
BASE COUNT         1160 a          331 c          480 g         1041 t
ORIGIN      
        1 aataaaatat aaaaattgag aattttataa tatatttgta gatttgagta taaaaaagtg
       61 ctaagttgaa aggagtaaaa tatggataag gttaatttag aaaggtatag ttgtgatata
      121 aatgttggtt taaataaaaa tcaacttcaa agtagaatag atgataattt aattaatgca
      181 tttgataatg gaaaaaccaa aacatataaa caaattttta aagacaatat atttacactt
      241 tttaatctca taaatattgt tttagtctgt ttattagttt cagttggttc ttttaaaaat
      301 accttattta tatttattgc tgtaattaat actattatag gagtaataca agagataaga
      361 gctaaaagat tattggacaa tctatctgtt atagtttcaa ataaggtatc tgtcataaga
      421 gaaaaagaga aaaaagagat tgatgtacaa gaattagtat tagatgatat tatgatttta
      481 aaaacaggta atcaaatttg tgcagattca aaagttttaa atggaaaatt agaggtaaat
      541 gagtctttgg ttacaggtga atctgatatt attataaaaa ataaagacga ttttttatat
      601 tctggaagtt ttgtagtttc tggagaagct tttgtaagag ttgaaaatat aggaaaagat
      661 aactatgcaa ataagatagt taatgatgca aagatttcta aaaaacataa ttctcaactt
      721 agaaattcat taaattcaat attaaaaatt gtaggtataa taataattcc tttaggaatt
      781 atattgtttg caaaacagca ttttggaaat ggagattcta tagctacatc tgtagtaggt
      841 acagtggcag ctgtaaatgg tatgatacca gagggattaa cattacttac gagcattgct
      901 ctagctgtag gaactataaa acttgctagt cataaaactt tagtgcaaga actgtactgt
      961 gtagagactc ttgctagagt tgatacacta tgtcttgata agacaggtac aattacagaa
     1021 ggtaaaatgc aagttgatga tatagtaatg ttggaagaag tggatattaa tgaaataatg
     1081 gggaatatat gtaattctct caaagatgat aatgcaacac taaatgcaat aagagataag
     1141 tataatgttt tagatacgta taaagctaag aatttaatac cattttcttc agaaagaaaa
     1201 tacagtgggg ttacctttga aaataaaggt acatatttat taggtgcatt tgagtttata
     1261 tttaaggaaa aaaataaaaa aattagaata gaagttgaaa aatattctaa aaaaggaaac
     1321 agagtaatag ttttagctca tagtgattct tatatggaag ataataatat tcctgaagat
     1381 ataaagccac tagcttttat attgatatta gataaaatta gagatgaagc taaggaaact
     1441 ttagaatttt tttacaatga aggtgtagat ataaaaatta tatctggtga caatcctata
     1501 acagtaagtg aggtagctag aaaagcaggt cttaaaacgg ctagtaattt tattgatgca
     1561 acaacactta aaaatgataa cgatatatac gaagcagttg ataaatacag tgtttttgga
     1621 agggtaagcc cacaacagaa aaaacaaatg attttagcat taaaaaaaca aaatcataca
     1681 gtagctatga ctggagatgg tgtaaatgat gtgctagcgc ttaaagaagc agattgcagc
     1741 attgccatgg catctggaag tgatgttact aagaatgttt ctaatttagt cttattagat
     1801 tcaaactttg catcaatgcc aaaggttgtt atggaaggac gaaaggtaat taataacatt
     1861 caaagagcat cttctttgtt tttagtaaag acaatttttt cattcttctt gtcactatta
     1921 acattattct tcttcagtag acagtatcca tttgttccta tacaattatc actaattgga
     1981 gctgtaacag tgggtatacc atcattcttc ttagctcttg aagcaaacaa aagtagaatt
     2041 tcaggaaact ttttactcaa tatattaaaa aatgctttac caggagcact atgtgtgaca
     2101 gtaaatgtaa ttattgttta caatatagtt gaatatttag gctatagttc aagtgtattt
     2161 tctacaatgt gtgctatatt aactggtgta tgtggtcttt taatattaag acaacaatgt
     2221 ttgccattta ataaagaaag attattttta attgtaagta tgactattgc atttgttatt
     2281 gggattctat ttttaggtgg attattctca tttgtagcat tgagtagaga attaattctc
     2341 ataactatgg cattagcaat attaatgcca attatgataa aagttatgtt atttgtcttg
     2401 gatgagatat tagagacaat tgttccagat ttaaattaat tttaaaatga tataaataag
     2461 agcagtttta gttgaactgc tctttttaga tgtgtttaat tttatataag aatatgtatt
     2521 tttattaatc agctatatat gagcaacagt agtcaacaac ttcattaacc tttaaatcaa
     2581 aacttgaatc actaggaaca ttaaattttt gcccttcttt ataagttaca aactcattgc
     2641 ttccaggcag ttttacatcc atacttccag caagcatctc cattatttct tcttctctag
     2701 tagaaaaagt atattctcct ggcaacatta atcctaaagt ttttctttct ccattaggca
     2761 gtattattac tctgctactt accttaccat caaaataaac gtttgccttc tttactgcag
     2821 taacattctt aaattcactc attagataaa acctccaaaa ttatttgtac atatatatta
     2881 tataaaaata atgtaaaaaa tgctatatat ttgcaaaaaa aaatttagta tttattaaaa
     2941 aaattaataa gaataaaaaa gagatgaaat tgcttaaatt gataaaaaat ataaaataaa
     3001 ttgcaaagta ag
//
LOCUS       DAMJYN010000189         2980 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.195, whole genome shotgun sequence.
ACCESSION   DAMJYN010000189 DAMJYN010000000
VERSION     DAMJYN010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2980)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2980)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2980
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.195"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            82..951
                     /locus_tag="PC466_003681"
                     /pseudo
     CDS             82..951
                     /locus_tag="PC466_003681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426876.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
     gene            1857..2564
                     /locus_tag="PC466_003682"
     CDS             1857..2564
                     /locus_tag="PC466_003682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HDF2771027.1"
                     /translation="MIFTKSNKYDKDFLMKNMMGPNCIKILEELTSKIKLEKGMRILD
                     LGCGKGISSIFLAKEFDATVFATDLWIEPTENYKRFKEFKLDDKIFPIQAEAHELPYA
                     EGFFDAVISIDSYHYFGNKEGFLDNHISPLVKEGGILAMAMPGLKEDFVDCIPDELIP
                     FWQDNMNFHSITWWNKLWSESESVIVEKCEALNCHDEAWKDWINCDNSYAINDKKMME
                     VENGKYFNTISLIARTK"
BASE COUNT         1204 a          259 c          477 g         1040 t
ORIGIN      
        1 agtaggaata cttaaacgta taaagtttat tatcggaaat ttctatatta atatgtagta
       61 attcaatatt attataaagg agtggttatt attaaggcaa ttgaacttta taaaaaatta
      121 gatttagaat ttaatattaa aaatattaat gatgattgga gttttatgaa ttttgaaaat
      181 gattttatca ctccagaatt tagaaaaaag tacatatgat tagtattaga taatgctcaa
      241 aatattaata aagtatacac aactactttt cctgataaag aaataattaa gcaagttata
      301 gataaagatg aaaaagatat tttaattttt tcacatcacg caatgggata catagcatca
      361 gatgaaggtt ttccatttca cgacatacca ctatcttata tggaagagat gaaaaatcgt
      421 agaatttctt tttatgtatt acattctcca ctagacaact atagtgacta ttcaacttct
      481 gttagttttg caaaagctat gggtttagaa atagtcaaac cattttgtaa atatgacgat
      541 aaaattgagg taggagttat atgtaaaaca tcactaaaat caatagaaga gattaaggaa
      601 ttaattaaaa aatctgttgg tcatgatgtg aaattgtatg attatggaga ttctgtatta
      661 aaagatggtt tagttgctat tgcagcaggg ggaggaagtt atccatttgt agcaagagaa
      721 gttgctgaac ttggtataaa tctatatatt actgggttta ctaagccttt aaaacatttt
      781 gaaccagtat tagagttcca tcaaatagca aaagataatt taattaatgt tataggtgct
      841 actcattatt ctacagaaaa atttgcgtgt atgggcatgg ttgattattt taaaaatcta
      901 ggtttagaat cagagttttt gcaaggaaaa tattacttag aggatttata ggacatatta
      961 aacaataaaa ataaacagtt agtaaaaatt tattttacta actgtttatt tttttaccta
     1021 tttatccagt gttttgaaaa aatctatctt tattttttaa actaagaaaa tagactttta
     1081 attgttgatt agaagattta gttttgatgt cttttaaatt atttttcgat attttttagt
     1141 ttattttttg atgtatttta gattattatt taggattgat tagaatttat aaatatttat
     1201 tttagattat tgtaaatatt tatttaaaaa aaatagaatt attatattta tgataataaa
     1261 tggtataata aaaggtaaag tgtcaaatat gcactaaatt aaataagtta attagtatat
     1321 aggttaaagt ggaagtaatt aaaacttatt aagtattaga aaatgacttc ttattagagt
     1381 aagtatctaa aatgatataa aaattatgat tactcattaa agtgactatt atagagtaga
     1441 taaaattgcc cataaaaata gctataatag agtggataag attactcatt aaagcaatta
     1501 ctatagagta gataaaatta ctcactaaaa taactataat agagtggata agattattca
     1561 ttaaagcgat tactgtggag tagataaaat tactcactaa aataactata atagagtaga
     1621 taagatactc attaaggtga ttattgtaga gtagataaaa ttacccatca aagttaatta
     1681 tcacatatta gataagatta ttcattaaag ttactatcac agagtggata aaattacaca
     1741 ttaaaattgt ctgttaaaga atgaataaaa aagagattgc tcaatataag aagcatataa
     1801 aaaatcaaac atataaaatt taataaataa taactgatag ggaaaggaaa gatagaatga
     1861 tatttacaaa aagcaataaa tacgataagg actttctcat gaaaaatatg atgggaccta
     1921 attgtataaa aatattggaa gaattaacaa gtaagataaa actagaaaag ggaatgcgta
     1981 ttttagactt aggttgtggt aagggtatat cttcgatatt tttagcaaag gaatttgatg
     2041 ctactgtatt tgcaacagat ttatggatag aaccaactga aaactataaa agatttaaag
     2101 agtttaaatt ggatgataaa atatttccaa tacaggcaga ggcacatgaa ctaccttatg
     2161 cagaaggttt ctttgatgcg gtgataagta tcgattctta tcactatttt ggaaacaaag
     2221 aaggattttt agacaatcat atatcacctc ttgtaaaaga ggggggaata cttgctatgg
     2281 caatgcctgg attaaaagaa gattttgtgg attgtatacc agatgaactc attccatttt
     2341 ggcaagataa tatgaacttc cattcaatta catggtggaa taaactttgg tctgaatcgg
     2401 agtctgtgat tgtagagaaa tgtgaagctt taaattgtca tgatgaagct tggaaggatt
     2461 ggataaattg tgataattca tatgctataa atgacaaaaa aatgatggaa gtagagaatg
     2521 gaaagtattt taatacaatt tctttgatag cgagaactaa ataattgtga tgaatttata
     2581 aaagtataag ataagtagaa atataagttg aatgagagta taagaagcat agaaatataa
     2641 gttgaattaa agtagaaggt aaataaaaat gtaagttaaa taaagagttt atacaaaaat
     2701 gattttttag attatttata cccaatcgag ttgcttaggt cagttgggta tttttatttt
     2761 tttaaagtta aattgcaaat actattgtgt gatatatatt ttaatactaa atgtttgttt
     2821 tataagaaat aaactaatag aaaaaatagt tttaacaatg aaagcaaaaa aggtattgat
     2881 gaagattaaa aattttatag taccatttta tatatttttt tatatatttt attatacttt
     2941 aaatcaaatt tcaaaatgat taagtatata tacccaaaag
//
LOCUS       DAMJYN010000190         2973 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.196, whole genome shotgun sequence.
ACCESSION   DAMJYN010000190 DAMJYN010000000
VERSION     DAMJYN010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2973)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2973)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2973
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.196"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            97..987
                     /locus_tag="PC466_003683"
     CDS             97..987
                     /locus_tag="PC466_003683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF2771028.1"
                     /translation="MAKLTLEHIKGNTYYIPLPTIVGVYVDGKDAILIDSGNNKDTAR
                     QVLRLLEEHNLSPKLIINTHSNADHIGGNAYLKNQTKCKIATTKIEGYFTENPILESA
                     FLYGGYPSKALKNKFLLAKESEVDYIIPSNGKIVDTELEAISLPGHYFEMIGVRTPDN
                     VLFVADSLTPENIITKYHFFFLLDIDSQFKTLEKLRMLEADFFVPSHSVKTTDIKSLI
                     NINKKKMEEIIDNIKKVCYEPVMIDEVIEKMCDLYNVKLDANQYVLVGSTIRSYITYL
                     YENNMVEYIFDGGKMMIKAV"
     gene            1205..2959
                     /locus_tag="PC466_003684"
     CDS             1205..2959
                     /locus_tag="PC466_003684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp23"
                     /protein_id="HDF2771029.1"
                     /translation="MYIMNKKFKKFSKKLSILILVLTMFLFNNLTANAQIKEDSIIGI
                     DRYETAGLIADRQTYDTVILVNGDKNLSDGLSSSGLAGAINAPILLTKKSEIPKATLN
                     RLDNKSLNVVKKVYIIGGYNTIENSVEKDIKRKGIQVERINGNNRIETSYNVAKKINE
                     VSSVKEVMLTNGFVGEADAMSIAPVVAKNKGAIILTDGKSVPFKTEGLNVYAIGGKSA
                     INEDLVNETKATRIGGNDRFETNKKVMEKFYNGATDFYITNGYQLVDALTLSPLAKEK
                     PIVLVADGSNKGILKGAKSITKVGGIDANIYKQCLDMIKYNNMDVTPNILKHLTSVEG
                     NEVSEILIESDNLGVVVEKTNTNKFEFDYVSVTNEKNCTFSVYKENSSNNVKNGKLVV
                     SAKKKIDKKDSDLQDMNGDNMINANKDRMVNVIKIGVPDKMYSNFKVDVESGSVELYN
                     IKGGATVDVNDGIANIVDNNVTNPFNINTNSGISGVTAETISSEIKFRANNGIVSVTA
                     TNINGNISLFGSDNKGTFDGIFKLNLKKEPSNLHLKLVGNGINKLPEGWSKDYILGNG
                     QPIIEVKNNGINNISIGE"
BASE COUNT         1242 a          272 c          525 g          934 t
ORIGIN      
        1 ataaaagaaa taaaaatata ttataaaaac aatttgattg gaattttcag aaaattaatg
       61 ctataattaa aagtaaattt aaagggaggt tataaaatgg ctaaattaac tctagaacat
      121 ataaaaggaa atacatatta tattccactc cctacaatag taggtgtata cgtagatggt
      181 aaagatgcaa ttttaattga cagtggaaat aataaggata cagctagaca agttttaaga
      241 ttattagaag aacataattt aagtcctaaa ttaataataa acactcattc aaatgcagac
      301 catataggag gaaatgcata tttgaagaat caaacaaaat gcaagattgc tacgactaaa
      361 attgaaggat attttacaga aaatccaata ttagaatcag catttttata tggtggctat
      421 ccaagtaaag cactgaagaa taaattttta ttagcaaagg aaagtgaagt tgattatatt
      481 ataccttcaa atggcaaaat tgtagataca gaacttgaag cgatttctct tccaggtcat
      541 tattttgaaa tgattggtgt tagaactcca gataatgttt tgtttgttgc agatagtctt
      601 acaccagaga atataattac taaatatcat tttttcttcc tactggatat agattcacag
      661 tttaagacac tagaaaaatt gagaatgtta gaggctgatt tctttgttcc aagtcactct
      721 gtcaaaacta cagatataaa aagtttgatt aatattaata agaagaagat ggaagaaata
      781 atagataata ttaaaaaggt ttgttatgag ccagttatga ttgatgaagt tattgaaaaa
      841 atgtgtgatt tgtacaatgt caagcttgat gctaatcaat atgtgttggt tggaagtaca
      901 atacgttctt atataactta tttatatgag aataatatgg ttgaatatat atttgatggt
      961 ggtaagatga tgataaaagc tgtgtaaata gtaataattt tcaaattata tgatgaaatt
     1021 gttttagtat gactgttatt tgaaaagtaa cataaaaaaa tttatataaa taagctaaga
     1081 tgattgatat aaagttactg ataattttaa ggtaatatat acgttactat aatattatgt
     1141 tattatttgt aaataagggg ataatttata agcaaattaa agaccttaat ttacaggagg
     1201 aatagtgtat attatgaata aaaaattcaa aaaattcagt aaaaaactaa gtatattaat
     1261 tttagttttg actatgtttc tttttaataa tttaactgca aatgcacaga ttaaagaaga
     1321 ttcaataata ggaattgata gatatgaaac agcaggactt atagcagata gacaaactta
     1381 tgatactgta atattagtta atggagataa aaatttatct gatgggcttt catcaagtgg
     1441 attagctgga gctattaacg caccaatact tttgactaaa aaaagtgaaa taccaaaagc
     1501 tactttaaat agactagata ataagagttt aaatgttgta aaaaaagtat atataattgg
     1561 tggttataat actattgaaa attcagtaga aaaagatata aaaagaaaag gtattcaagt
     1621 ggaaagaata aatggtaaca atagaattga aactagttat aatgtagcta aaaaaataaa
     1681 tgaagtaagt agtgtaaaag aggtaatgct tacaaatgga tttgtaggag aggctgatgc
     1741 tatgagtata gcacctgtag ttgcaaaaaa taaaggagct ataatactta cagatgggaa
     1801 atcagttcca tttaagactg aaggtttaaa tgtttacgct ataggtggca aatctgcgat
     1861 aaatgaggat ttagtaaatg aaactaaagc aactagaatc ggaggaaatg atagatttga
     1921 gaccaataaa aaggtaatgg aaaagtttta taatggagcg acagattttt atataacaaa
     1981 tggatatcaa ttagtagatg cactaacatt atctccttta gccaaagaaa aaccaatcgt
     2041 tttagttgct gatggaagta ataaaggtat tttaaaagga gctaaaagta taacaaaagt
     2101 tggaggtatt gatgccaata tatataaaca gtgtttagat atgattaaat ataataatat
     2161 ggatgtgact ccaaatattt taaaacactt aacttcagtt gaaggaaatg aagtttctga
     2221 aatacttata gaatcagata atttaggtgt ggttgttgaa aagacgaata ccaataaatt
     2281 tgagtttgat tacgtaagtg taactaatga aaaaaattgt actttttctg tatataaaga
     2341 aaattcttct aataatgtaa aaaatggaaa gctagttgta agtgctaaga aaaaaataga
     2401 taagaaagat agtgatttgc aagatatgaa tggcgacaat atgataaatg caaataaaga
     2461 taggatggta aatgtgataa aaattggagt tcccgataaa atgtattcta attttaaagt
     2521 agatgttgaa agtggttcag tagaacttta taatattaaa ggaggagcta ctgttgatgt
     2581 caatgacgga attgctaaca ttgttgataa caatgtgaca aatcctttca atataaatac
     2641 taatagtggg atttcaggtg taacagctga aactatatca tctgagataa aatttagagc
     2701 aaacaatgga attgtaagtg taacagctac aaatataaat ggcaatataa gtttatttgg
     2761 aagcgataat aaaggtacct ttgatggaat atttaaatta aatctgaaaa aagaaccatc
     2821 aaatttacac ttgaagttag ttggaaatgg gataaataaa ttgccagaag gttggtctaa
     2881 agattatatt ttaggaaatg gacaaccaat tattgaagtt aaaaataatg gcataaataa
     2941 tatatcaatt ggagaataaa aacatatgaa aat
//
LOCUS       DAMJYN010000191         2921 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.197, whole genome shotgun sequence.
ACCESSION   DAMJYN010000191 DAMJYN010000000
VERSION     DAMJYN010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2921)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2921)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2921
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.197"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            316..2451
                     /gene="rnr"
                     /locus_tag="PC466_003685"
     CDS             316..2451
                     /gene="rnr"
                     /locus_tag="PC466_003685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HDF2771030.1"
                     /translation="MIPGLKESLLGLINESAYNPLKKEELAEIFDIHSSEMPMFYNFL
                     NELEEDGYICFTKKGKIVSPNQMGYFVGKFVSHKKGFGFVESDVEYTQDLFISSDNIN
                     GAMHNDRVMAEIVVPATEEKRAEGRIVKVIKREITRIVGTFQSSKTFGFVTPDNKKFT
                     KDIYIPKKHFSGAVDNDKVVCEITVWPQEDRKPEGKIIEILGQKGERGVEIDSIIREH
                     GLPEEFPKKVLQEAEAVAVEIPQEEIKRRRDLRDLNIFTIDGDDAKDLDDAISIEVLP
                     NGNFKLGVHIADVTHYVREKNKLDKEALKRATSVYLVDKVIPMLPKTLSNGVCSLNPF
                     EDKLTLSIFMEIDHKGNVVKHEICESVINSKARMTYTEVSDILEKDDEKLKKTFEHVV
                     EDFKNAEILAKILMSRREKRGAIDFNFPEAKIILNGKGEVVDIKPYERRISNKIIEEF
                     MLISNETIAEHFYWMGIPFVYRIHETPSLEKMEELSKFISTFGYIIKGDKEEVHPKAL
                     QGIIEKIKGKKEEGAISTIMLRSLKQAKYSPECSGHFGLAAKFYCHFTSPIRRYPDLQ
                     IHRIIKESLNNKISGKRQEQLTTIVDYASVQSSEKERKAELAERDVHDFYKALYMKDK
                     VGQEFEGVVSSVTSFGIFVELDNTIEGLIRLANMNDDYYIYDESSYSVLGERTKKSYK
                     IGDLVKIKVESVNVDFKEIDFEIVEKIEE"
BASE COUNT         1287 a          269 c          528 g          837 t
ORIGIN      
        1 atatgagatg aatattttac caatcctatt tgatggtgta taattatgag ataaagagta
       61 atttaagcaa ttatgataaa gaataactta agtaattata atgatattta caaataattt
      121 ataaaacatc ataatttgtt tgaagttagt atgacaaagc ttacattaaa tcaaaaatat
      181 aaataagtaa ttttaacttg taataataat aagaaaatat agaaaattat gtgataagta
      241 aaaaatgttt tatctgaaga aatataaaag acaatataaa taataatata atgaaaagta
      301 aaacaggagg gaaaaatgat accaggactt aaagaaagtt tgctaggatt aataaatgaa
      361 agtgcatata atcctctaaa aaaagaagaa ttagcagaaa tatttgatat acattcatca
      421 gaaatgccaa tgttttataa ttttttaaat gaattagaag aagatggtta tatctgcttt
      481 actaaaaaag gaaaaatagt atctcccaat caaatgggat actttgttgg aaaatttgta
      541 tcacacaaaa agggttttgg atttgtagaa tctgatgttg aatatacaca ggatttattt
      601 atctcaagtg acaatataaa tggtgctatg cataacgata gagttatggc agaaatagta
      661 gtacctgcaa ctgaagaaaa gagagcagaa ggaagaatag taaaagtaat aaagagagaa
      721 ataactagaa tagtaggtac tttccaatca agtaaaactt ttggatttgt aacaccagac
      781 aacaagaaat ttactaaaga tatatatata cctaaaaaac attttagtgg agcagtagat
      841 aatgataagg tagtatgtga aattacagta tggccacaag aggatagaaa accagaaggc
      901 aaaattatag agatactagg tcaaaaaggt gaaagaggcg tagaaataga ttctataata
      961 agagaacatg gtcttccaga agaatttcca aagaaagtat tgcaagaagc agaagctgta
     1021 gctgttgaga ttcctcaaga agagataaaa agaagaagag atttaagaga tttaaacata
     1081 tttactatag atggagatga cgcaaaagac ttagatgatg ccatatcaat agaagtatta
     1141 cctaatggaa acttcaaact aggagttcac atagctgatg ttacacatta tgtaagagag
     1201 aaaaataaac ttgataagga agccttaaaa agagctacat cagtttattt agtagataaa
     1261 gtaattccaa tgttgccaaa aactctttca aatggagtat gtagcttaaa tccatttgaa
     1321 gataagttaa ctctttctat atttatggaa atagaccata aaggaaatgt ggttaaacat
     1381 gaaatatgtg aatctgtaat aaattcaaaa gctagaatga cttatacaga agtatctgat
     1441 atattagaaa aggatgatga aaaacttaaa aagacttttg aacatgttgt tgaagatttt
     1501 aaaaatgctg aaattttagc taagattctt atgtcaagaa gagaaaaaag aggagctata
     1561 gacttcaatt tcccagaggc aaagataatt ctaaatggaa aaggcgaagt tgtagatata
     1621 aagccatatg aaagaagaat atctaataag ataatagaag aatttatgct tataagtaat
     1681 gagacaattg ccgaacattt ttactggatg ggaataccgt ttgtgtatag aatacatgag
     1741 acaccatctt tggaaaaaat ggaagaattg agtaagttta tatctacatt tggatatata
     1801 ataaaaggtg ataaagagga agtacatcca aaagcattac aaggtataat agagaaaata
     1861 aagggcaaaa aagaagaagg agctatcagt actataatgc ttcgttcttt aaaacaagct
     1921 aagtactcac cagaatgtag tggacatttt ggattagcag ctaaattcta ctgtcacttt
     1981 acttcaccaa taagaagata tcctgacctt caaattcata gaataataaa agaatcttta
     2041 aataataaaa taagtggaaa aagacaagaa cagcttacta ctatagtgga ttatgcatct
     2101 gttcaatcat ccgagaaaga aagaaaggca gagttagctg aaagagatgt acatgatttc
     2161 tataaggctc tttatatgaa ggataaagtt ggtcaagaat ttgagggtgt tgtatctagc
     2221 gtaacttcat ttggaatatt tgttgagtta gataatacta tagaaggatt gataagactt
     2281 gcaaatatga atgatgatta ctatatttat gatgagagtt cttatagtgt tttaggagaa
     2341 agaactaaga agtcatataa gataggagac cttgttaaga taaaggttga aagtgttaat
     2401 gtagatttta aagaaattga ctttgagata gttgaaaaaa tagaggagta gataaaacag
     2461 ctaaaataag agataacaag ttgtagtatt tatgatatgt ataaatatat agtgcacaat
     2521 actctataaa ataaatgata aaaataggta attaagaaat atctaatgga aatagttaac
     2581 ttaaagataa ataattaaga aatatttaat gaaagtagct aattgaaaaa taagtaattg
     2641 agaaatattt aatagaaaga gctaactgaa agataagtaa ttaagaaaca tttaatagaa
     2701 aaagccaact gaaaaataaa taattaagaa atgtttaatg gaagtgacta attgaaaaat
     2761 aagtaattaa gaaatgctta atagaagtgg ctaattgaaa aataagtaat taagaaatgt
     2821 ttaatagaag tggctaattg aaaaataagt aattaagaaa tgtttaatag aagtggctaa
     2881 ttgaaaaata agtaattgag aaacatttaa tagaagaagc t
//
LOCUS       DAMJYN010000192         2855 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.198, whole genome shotgun sequence.
ACCESSION   DAMJYN010000192 DAMJYN010000000
VERSION     DAMJYN010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2855)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2855)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2855
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.198"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            105..488
                     /locus_tag="PC466_003686"
     CDS             105..488
                     /locus_tag="PC466_003686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HDF2771031.1"
                     /translation="MNLSKKIEDKRKAKQRAEKVKKAKIATAGVVLGAVTGAVSGVLL
                     APKSGKETREDIKDASQQIAEKINMKTVDVKGKVSEKLEDKKGNFIESKKKIKKYIDN
                     KKSVENSSEEDKIIDIVEPVSVTEE"
     gene            490..840
                     /locus_tag="PC466_003687"
     CDS             490..840
                     /locus_tag="PC466_003687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2771032.1"
                     /translation="MDNTITINISIIYVLLAILACIALVYLIIVLVKLHKILNNVGTM
                     LNENTQNINTTLNNLPNVVETFGEVGENMKDVTEVVTEVTADFLVTKDSVKSNMDVIV
                     DILTIIKNIFLDKK"
     gene            complement(934..1392)
                     /locus_tag="PC466_003688"
     CDS             complement(934..1392)
                     /locus_tag="PC466_003688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2771033.1"
                     /translation="MIRTKVVELIATVCRENKPHKWVDENYTPYDKSGKVELMSIEDL
                     NELISSSGRADFLYSSRLQKLLNEVYINQSRASYISGCGLFWSSYWDILEEKFEEWLY
                     NSYIFFDEDDEYLEGMEDFELECKDVLMDVIETTSIDIYVQMIKRNITNY"
     gene            complement(1437..2225)
                     /locus_tag="PC466_003689"
     CDS             complement(1437..2225)
                     /locus_tag="PC466_003689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDF2771034.1"
                     /translation="MKVVIIPGHTLIGKGTGAVGYINESKETRILNDLIVKWLKIGGA
                     TVYTGRVDESSNHLADQCAIANKQETDLAVQIHFNSNATTSTPVGTETIYKTNNGKTY
                     AERVNTRLATVFKDRGAKSDVRGLYWLNHTIAPAILIEVCFVDSKADTDYYVNNKDKV
                     AKLIAEGILNKSISNSQGGGENKVYENVIVYTGDADKVAAQILHWQLKDSLIIEASSY
                     KQGLGKKVYVVGGEANKLVKGDVVINGADRYETVKLALQEIDKL"
     gene            complement(2364..2801)
                     /locus_tag="PC466_003690"
     CDS             complement(2364..2801)
                     /locus_tag="PC466_003690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dCMP deaminase"
                     /protein_id="HDF2771035.1"
                     /translation="MNKKLENRCSWQEYFMRLCETVAERGTCDRAYVGAIIVNSENRI
                     VSTGYNGSISGDKHCSEVGHEMRDGHCIRTIHAEQNALYYCAKEGISVKDCSIYVTHF
                     PCLNCTKAIIQAGIKHIYYRTGYRIDEYAIKLLQSSNVLYTKL"
BASE COUNT         1013 a          447 c          339 g         1056 t
ORIGIN      
        1 aaaagaattt ttattgattt ttaaaaattt agttagaaac tatatcatta tggtaaagaa
       61 tgtattataa tgtttagaaa tattataata aggagcgatt aaacatgaat ctatcgaaga
      121 aaatagaaga taaaagaaaa gctaaacaga gagctgaaaa agttaagaaa gctaaaattg
      181 ctacagctgg tgtggtatta ggagctgtta ctggtgcagt gagtggagta cttttggctc
      241 ctaaatctgg aaaagaaaca agagaggata taaaagatgc ttcacaacaa attgctgaaa
      301 agataaatat gaaaactgta gatgtaaaag gcaaagtatc tgagaagcta gaggataaaa
      361 aaggaaactt tatagaatca aagaaaaaaa taaaaaaata tatagataac aaaaagagtg
      421 ttgaaaattc tagtgaggaa gataaaataa tagatatagt tgaaccagtt agtgttactg
      481 aggaataata tggacaatac aataacgatt aacataagta taatatatgt attattagct
      541 atacttgctt gtattgcttt agtttattta attattgtac ttgttaaact acataagatt
      601 ttaaataatg ttggaactat gttaaatgaa aatactcaaa atataaatac aactttaaat
      661 aatcttccta atgttgtaga aacttttgga gaagtaggag aaaatatgaa agatgtaaca
      721 gaagtagtta ctgaagttac agcagatttt cttgttacta aagacagtgt caaatcaaat
      781 atggatgtta tagtcgatat attgactata attaaaaata tttttctaga taaaaagtaa
      841 taaatttaat ataaaataag atataattta aacgacctta aaataacatt tataaggtcg
      901 ttttttatta gcttgatttg acactatgtg tttttaataa ttggtaatat tcctctttat
      961 catttgaaca tatatatcta tgcttgttgt ttcaattaca tccataagaa catctttaca
     1021 ttcaagctca aaatcttcca ttccttctaa atattcatca tcttcatcaa aaaagatata
     1081 agaattatat agccattctt caaatttttc ttcaagtata tcccaatacg aactccaaaa
     1141 taatccacaa cctgatatat aagatgctct actttgattt atataaacct catttagaag
     1201 cttttgtaat ctactgctat aaagaaaatc tgctcttcca ctgcttgata ttaattcatt
     1261 taaatcttct attgacatta attcaacttt accactttta tcataaggag tataattttc
     1321 atcaacccat ttatgtggtt tgttttctct gcatactgtt gctatcaact ctacaacttt
     1381 tgttcttatc atttttttat cctaacttat ttatttttta taaaataatc atgattttat
     1441 aatttatcta tttcttgtaa tgctaattta acagtttcat atctatcagc accatttatt
     1501 actacatcac cttttacaag tttattagct tctccaccta caacataaac ctttttacct
     1561 aaaccttgct tataactaga cgcctcaatt attaaagaat ctttcaattg ccaatgtaaa
     1621 atctgagcag ccactttatc agcatcacct gtataaacga ttacattttc atacacttta
     1681 ttttcccctc ccccttgaga atttgatata gatttgttta gtataccttc tgctatcaat
     1741 ttagcaactt tatctttatt attaacataa taatctgtat ctgctttact atctacaaaa
     1801 catacttcta ttaatattgc tggtgcaata gtatgattaa gccaataaag acctctaaca
     1861 tcagactttg cacccctatc tttgaatact gtagctaacc tagtattcac tctttctgca
     1921 taggttttgc cattattagt cttatatatt gtttctgtcc ctactggagt tgaagttgta
     1981 gcatttgaat taaaatgaat ctgaacagcc aaatcagttt cctgtttatt tgctatagca
     2041 cattggtctg ctaaatgatt acttgattca tcaactcttc ctgtataaac agtagctcca
     2101 cctattttaa gccatttaac aattaagtca ttcagtattc ttgtttcttt gctttcgttt
     2161 atatacccaa cagctcctgt accttttcca attaaagtgt gccctggtat tattactact
     2221 ttcaaactaa catctccttt acaattaaat ttaacttcta tttaatatat gcataaccta
     2281 gaattttgtt tctttttata tcttatactt ttattataac ccattttgta aaaatataga
     2341 atattaagta aataatgtta aaattataat tttgtatata agacattact tgattgcaat
     2401 aattttatag catattcatc tattctatat ccagttctat aatatatatg tttaattcca
     2461 gcttgaatta tagccttagt acaatttaag caaggaaagt gagttacata aatagagcaa
     2521 tctttaactg aaataccttc ttttgcacaa taataaaggg cattttgttc agcgtgaatg
     2581 gttctaatac aatgtccatc tctcatttca tgaccaactt cactacaatg cttatctcca
     2641 gaaatactac cattatatcc agtagacact attctgtttt ctgaattgac aattatagct
     2701 cctacataag ctctatcaca agttcctctt tcagctactg tttcgcacag tctcataaaa
     2761 tattcttgcc atgagcatct attttcaagt tttttattca aatcatatac ctccaaaatt
     2821 tatatctaat atataagatt tataccttaa aaata
//
LOCUS       DAMJYN010000193         2844 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.199, whole genome shotgun sequence.
ACCESSION   DAMJYN010000193 DAMJYN010000000
VERSION     DAMJYN010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2844)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2844)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2844
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.199"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(583..1113)
                     /locus_tag="PC466_003691"
     CDS             complement(583..1113)
                     /locus_tag="PC466_003691"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2771036.1"
                     /translation="MFNKKKYETFVNNLKRNIGVYNQSEMNFTVTSETIRKKYQDKGE
                     PLQYMLEFEFDLSGNTGYYYYTLKKRVEMPFEVDISKLTIASVVFEDKELNDFLNQNG
                     VTYSVIKDNKATMPQPALSVSKQNANVIGGFEADYITPIVKQNNPDSKISDDELNRII
                     KESKLMTSFINRHTSH"
     gene            complement(1166..1357)
                     /locus_tag="PC466_003692"
     CDS             complement(1166..1357)
                     /locus_tag="PC466_003692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005809677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2771037.1"
                     /translation="MENQIRTLRKEQKLSQKTISERVDVSRQTINAIENNKYDPTLKL
                     AFRLADELNTTVDELFKKE"
     gene            complement(1406..2023)
                     /locus_tag="PC466_003693"
     CDS             complement(1406..2023)
                     /locus_tag="PC466_003693"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2771038.1"
                     /translation="MTKVTNFKTYKKGVDMGKRLESAMNFDSETFFKSIDIADSYIDS
                     YKDVMSYIYTSHKLLTLYDVALIFNGLAHNREIPYEAHQVIDHICQSAGFYMIVNNEL
                     MKRRSCVYGVKANIIKNKERHFHESSYRFFKAIMEEPESVTPYDVCALVLCVELLGNF
                     EAPVYHTITMPFKRYMKVSEHDYIQNRVAYNQSLMKRYIYRPSIK"
BASE COUNT          902 a          492 c          375 g         1075 t
ORIGIN      
        1 ggtgataaaa atgacaaaat caaaaatcaa aacaattatt aattatgctt taggcgtatt
       61 agtcatccta attgctctat tcattatctt ttatttataa catgctcaat aaacaaacgg
      121 ttcacggttc acggttcact ataatagtgt tggttgttat cttaagtaaa tgctagtagg
      181 cagttaaaca agcggtatag tttccgcttc tttaatattt atttatattg attttcagat
      241 gagacgcatt aacgaagata ctaacgcaac cataaatatt atatacaata accagactaa
      301 atattcggct aatcgtttag tcaataatga taatcccaaa tatgttataa aagatgctat
      361 aaaagcagct gcacaataca ccgcaatgat aagaattatt ttatttaatt ccatttcttc
      421 tcactccgtt ttacttaact tctatttctt ttcaacttaa tttgttagtt tgaatcatca
      481 aatttatata agcctgcgat tatcccgctt cttttcttct tattcatctg tattacatgt
      541 taatagcatc taacttataa tacataccgt catattgtcc ctttagtgac ttgtatgtct
      601 atttataaat gaagtcatta atttagattc tttaatgatt ctatttagtt catcatcact
      661 tattttacta tcagggttat tttgtttaac gataggggta atatagtccg cttcaaatcc
      721 accgattaca tttgcattct gttttgacac tgacaaggca ggttggggca ttgttgcttt
      781 attatcttta atcacgctat atgtaacacc attctgatta agaaagtcat taagctcttt
      841 gtcttcaaat actacagacg ctattgttaa ctttgaaata tcaacttcaa acggcatttc
      901 aacacgtttc ttaagcgtat aataataata ccctgtatta cccgacaaat cgaattcaaa
      961 ttcaagcata tactgaagcg gttcgccttt atcttgatac tttttacgaa tcgtttcgct
     1021 tgttaccgta aaattcatct ctgattgatt atatacgcct atatttcgct ttagattatt
     1081 aacaaaggtt tcatacttct ttttattaaa catgcttata tctcctctct aaatacgttt
     1141 aaaattcatc ttatggttaa catgtttatt cttttttaaa taattcatct accgtggtat
     1201 taagttcatc tgctaaacga aacgctaact ttagcgtcgg gtcatatttg ttattttcta
     1261 tcgcattgat cgtttgtcta gatacgtcca cacgttcact aatggtcttt tgtgacaact
     1321 tttgttcttt ccttaatgtt ctaatttgat tttccatagt tttgtccctt taatcctatc
     1381 ttcagtgcat tcacatattt agctattatt tgatacttgg tctgtatata taccgcttca
     1441 tcaaactttg attatacgct actcgatttt gtatatagtc gtgttctgat actttcatat
     1501 atcttttaaa aggcattgta attgtgtgat acacaggtgc ttcaaaattg cccaaaagtt
     1561 ctacacataa taccaaagca catacatcat acggcgttac actttcaggt tcttccatga
     1621 tagctttaaa gaaacggtac gatgattcat gaaaatgacg ctctttattc ttaataatat
     1681 tagccttcac accatacaca caacttctac gcttcataag ttcattgtta acaatcatat
     1741 aaaatcctgc actctgacat atatggtcta taacttgatg ggcttcgtat ggtatttcgc
     1801 gattatgtgc taaaccatta aatattaatg ccacatcgta taatgtgagc aatttatgag
     1861 acgtgtatat gtaagacatc acatccttat aactatcaat gtaactatca gctatatcaa
     1921 tagatttaaa aaaagtttcg ctatcaaaat tcattgccga ttcaagacgt tttcccatat
     1981 ccacgccttt tttatatgtt ttgaaattcg ttactttggt cattatttca cctctttata
     2041 aattatatta agtaataaag taatggtatg cgtttattat aactagtata catatgctaa
     2101 ttatattctt atatgtaaaa tgtttttgac attttcaata tacattttcg cttgttttaa
     2161 gtcaaatact tttgacactt aagacgtgga attgctatat tggttacagg acaaaagaaa
     2221 ttatgcgatg tatatacaac atctcttttt acgcacagga atagagaaaa acctcattca
     2281 cttaaagtcg tccaaagctt tttaagtgag tgaggtttta ttacatttat actaacgtac
     2341 actacgtaca caattaaatt aaaattagaa gcggtgcgta aaccgcttct tcaatcgaac
     2401 ttattaaatt aagccaaaat aaccatccca acttttgaca gagtaggaag aatggttatt
     2461 aagtaatttc cgaaaagtca ccgtcttttt aacgggctta ctgaggcacg agtgttagcg
     2521 cacttatgcc ttttaacaat catcggctta atactaatta gaaataacca aaaattattt
     2581 tcaattttag cgtaattcta ttatattaca tgatgttatc ttttatcaaa cattcattat
     2641 aagtgtttaa gtagcctctt ctatttgttt atacagtatt tgatttgaaa atttttaaat
     2701 tcatcatacg taagaataat gatagcttat atccagtcat aggcttttga caataaactt
     2761 tacactgcaa tttatgtgat atgatgataa aataataggt aattaaaact taaatctaac
     2821 ccctgataca tctttaattt tggg
//
LOCUS       DAMJYN010000194         2791 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.200, whole genome shotgun sequence.
ACCESSION   DAMJYN010000194 DAMJYN010000000
VERSION     DAMJYN010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2791
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.200"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            179..1102
                     /locus_tag="PC466_003694"
     CDS             179..1102
                     /locus_tag="PC466_003694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2520 domain-containing protein"
                     /protein_id="HDF2771039.1"
                     /translation="MGSGKVGTSLANYFLSKGYCVSGFYGRNQLSLLESINLTKTKIY
                     SNLRDIIYENDILFITTSDDSIEIIDKKLSKFNLKHKYICHTSGSLKSSILFCSKKAG
                     ALIYSIHPIFAFSNKNTNIKKMKDICFSIEGDNEQDDLVIQNFIDGLGNQFFIRDKDT
                     SSTYHLANVLVSNLVLSLLDIGVSYFIKLGLSEEESLKAISPLVKKNIENILDNGFTK
                     ALTGPVSRGDITPIRKHLSVLNKKDEDIYKILSLNLLKIIALGNDNSLKGTKNITIEN
                     AIENLISKSEKYKEIYKLLGGKNDEKYHTDF"
     gene            1077..1904
                     /gene="panB"
                     /locus_tag="PC466_003695"
     CDS             1077..1904
                     /gene="panB"
                     /locus_tag="PC466_003695"
                     /EC_number="2.1.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011721175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate
                     hydroxymethyltransferase"
                     /protein_id="HDF2771040.1"
                     /translation="MKNTIQTFKNAKYEGKKLSMLTAYDYSIAKIMDECDINGILIGD
                     SLGMVIKGEENTLSVTIDEIIYHTKAVKNGAKNALIVSDMPFLSYHVSIEDAVKNAGR
                     LIKEGGAHAVKLEGGSNVIKQIESIVNAQIPVMGHLGLTPQSVNSFGGFKVQGNTSET
                     ARQLIEDAKLIEKAGAFSIVLEGVPTKIADMVTNSISIPTIGIGAGINCDGQILVYQD
                     MLGVFGDFVPKFVKQYANIGDIMKDSIKNYILEVNTGAFPQEKHSFSINESELEKLY"
     gene            1923..2771
                     /locus_tag="PC466_003696"
     CDS             1923..2771
                     /locus_tag="PC466_003696"
                     /EC_number="6.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantoate--beta-alanine ligase"
                     /protein_id="HDF2771041.1"
                     /translation="MLVKEIKLLRNIIKDWRKHGYSIGLVTTMGFLHEGHQSLIKKAV
                     KENDKVVVSVFVNPTQFGPNEDFNSYPRDIDKDFKYCMDSGATVVFNPSPEEMYLKGN
                     CTTINVSGLTDFLCGAKRPVHFGGVCLVVSKFLNIVTPDKAYFGEKDAQQLAVIKRMV
                     KDLNINTEIIGCPIIRENDGLAKSSRNTYLSEEERKSALILNKSLSLAKEELVKGNLN
                     PKNIKELITAKINSEHLAKIDYVEIVDSETLQPVKQIEHSILVAIAVFIGKTRLIDNF
                     TFELNI"
BASE COUNT         1106 a          337 c          459 g          889 t
ORIGIN      
        1 attaattgtc aattttttat gaaaatggta agatatttat ggatggtatc ttgttataag
       61 aactatactt taaatgtttt taattatttt gtcttatgta actcatatcc tcaggaatga
      121 gattagaaat taagatgttg tatcacaaag tggaggtgat actattaaaa taggctttat
      181 tggttctgga aaagttggaa catctttggc aaattatttt ttatcaaaag gttattgtgt
      241 ttcaggcttt tatggaagga atcaattatc tttattagaa tcaataaatt taacaaaaac
      301 aaagatttac agcaatttga gagatataat ttatgaaaac gatatattat ttattacaac
      361 atcagatgat tctattgaaa ttatagacaa aaaactttcc aaatttaatt taaaacataa
      421 atacatttgc cacacaagtg gctctttaaa atctagtata ttgttctgtt caaaaaaagc
      481 aggtgcatta atttattcta tccatcctat atttgcattt tccaataaaa ataccaacat
      541 aaaaaaaatg aaagacattt gtttttccat agaaggtgat aatgaacaag atgatttagt
      601 tattcaaaat ttcatagatg gtttgggaaa ccaatttttt ataagagata aggatacttc
      661 atccacttat catctagcta atgttttagt ttcaaattta gtattatctt tactagatat
      721 aggagtaagt tactttatta aattaggttt atctgaagag gaatctttaa aagctatcag
      781 tcctttagta aaaaaaaata tagaaaatat acttgataat ggctttacta aagctcttac
      841 tggtcctgtt tctcgtggag atataacacc aataaggaaa catctatctg tattgaataa
      901 aaaagatgag gatatctaca aaatactatc cttaaaccta ctaaaaataa ttgccttagg
      961 aaatgacaat tcattaaaag gtacaaaaaa tattactata gaaaatgcaa tcgaaaattt
     1021 aataagtaaa tctgaaaaat acaaagaaat ttacaaactt ttaggaggaa aaaacgatga
     1081 aaaataccat acagactttt aagaacgcta aatatgaagg aaaaaaacta tctatgctta
     1141 ctgcttatga ctactcaatt gcaaaaataa tggatgaatg tgatataaat ggtattttaa
     1201 taggcgattc attaggaatg gtcataaaag gtgaagaaaa cactctatct gttactatag
     1261 acgaaattat atatcataca aaagctgtaa aaaatggtgc aaaaaatgcc ttaatcgtaa
     1321 gtgatatgcc ttttctatct taccatgttt ctatagaaga tgcagttaaa aacgctggta
     1381 gacttataaa agaaggagga gctcatgctg taaagttaga aggtggctca aacgttataa
     1441 agcaaataga aagcattgta aatgctcaga tacctgtaat ggggcattta ggattaactc
     1501 ctcaatcagt aaattcattt ggtgggttta aggttcaagg aaataccagt gaaacagcaa
     1561 gacaacttat tgaagatgct aaattaatag aaaaagcagg tgcattctct attgtccttg
     1621 aaggagttcc tacgaaaata gctgatatgg taactaattc tatttcaatt cctacaatag
     1681 gtataggggc aggaattaac tgcgatggac aaattttagt ttatcaagat atgttgggag
     1741 tgtttggaga ttttgttcct aagtttgtaa agcagtatgc aaatatagga gatataatga
     1801 aagattcaat taaaaattac atcctagaag ttaatacagg tgcatttcca caagaaaaac
     1861 acagcttttc aataaatgaa tctgagttag aaaaattata ctaatattaa ggatggtaca
     1921 aaatgcttgt aaaagaaatt aaattactaa gaaatataat caaagattgg agaaaacatg
     1981 gctattctat agggcttgtt acaacaatgg gatttttaca tgaaggacac caaagtctta
     2041 taaaaaaagc tgtaaaagaa aatgataaag tagtagtgag tgtatttgta aatccaactc
     2101 aatttggacc aaatgaagat tttaatagct atccaagaga tatagataaa gattttaaat
     2161 attgtatgga tagtggagca acagtagtct ttaacccatc accagaagaa atgtatttaa
     2221 aaggtaattg tactaccatt aatgtttctg gacttacaga ttttctttgt ggagctaaaa
     2281 gacctgttca ttttggaggt gtctgcctag ttgtttcaaa gtttctaaat atagtaacac
     2341 ctgataaagc ttattttgga gagaaggatg cccaacaatt ggctgtaatt aaaagaatgg
     2401 tcaaggattt aaacataaat acagaaataa taggctgtcc tataattcgt gaaaatgatg
     2461 gattagcaaa aagttcgaga aatacatatc tctctgagga agaacgaaaa tctgctctaa
     2521 tattaaataa gagcttaagt ttagcaaaag aagaattagt aaaaggcaat ctaaatccaa
     2581 agaatataaa agaattaata acagctaaaa taaattctga acacttagca aaaatagact
     2641 atgttgaaat tgtagatagt gagacattac aacctgttaa gcaaatagaa cattctatcc
     2701 ttgtggcaat tgctgtgttt ataggaaaaa ccagactaat tgataatttt acatttgagt
     2761 taaatatata gtatataatt ttatataata t
//
LOCUS       DAMJYN010000195         2763 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.201, whole genome shotgun sequence.
ACCESSION   DAMJYN010000195 DAMJYN010000000
VERSION     DAMJYN010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2763)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2763)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2763
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.201"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            995..1384
                     /locus_tag="PC466_003697"
     CDS             995..1384
                     /locus_tag="PC466_003697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF2771042.1"
                     /translation="MTIKKLPQSELKIMKFIWKSDSKVTSRDIVLGMEQKYQWKQTTT
                     LTLLSRLVVKRFLNSQKIDKYTHYEVLIKEKEYIGVETRDFFRNIHDSSIKSLLLSLH
                     ENINLSKDDILLIEEWIKNLKEEEKDV"
     gene            2129..2599
                     /locus_tag="PC466_003698"
     CDS             2129..2599
                     /locus_tag="PC466_003698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase/bleomycin resistance/dioxygenase
                     family protein"
                     /protein_id="HDF2771043.1"
                     /translation="MKYQVSLLAVKDIEVSKKFYKELFEQEIELDLGKNVTFKGGFAI
                     QEDFAWLTGINPDTIIQKSNNMELYFEVDDFDEFIEKLNYYKDVEFVHKPLKHEWQQR
                     VVRIYDPDKHIIEIGESMEVIARRYLSEGYSVEETSKIIQHPIEFVKQCENSKE"
BASE COUNT         1260 a          169 c          482 g          852 t
ORIGIN      
        1 taatgaaaaa atttaaattt tgtaatatat aaataaaaaa actctaaaat agaaggatat
       61 aattatatag aatgtttcaa ttaaacaagg caaaaactat aatcttaaaa ttaaaattaa
      121 cattattctt aagaagtaag aaatttaaga agtaaaaagt ttagtgataa gtggtagtaa
      181 gcaagaaatt tagaaagtag gaagtttagt gataagtggt agtaagcgag aaatttagaa
      241 agtgggaagt ttagtaataa tttgtagcaa gtaagaaatt taggaagtag gaagtttagt
      301 aataatttgt agcaagtaag aaatttaggg agtaggaagt ttagtagtaa taatttgtag
      361 caagtaagaa atttagggag taggaagttt agtaataatt tgtagtaagt aagaaattta
      421 gaaagtagga aatttagtaa taatttatag taagtaagaa atttagaaag taggaagttt
      481 agtaataatt tatagcaagt aagaaattta gaaagtagga agtttagtag taatttatag
      541 taagtaagaa atttagtaag tgagaagttt agttataatt tatagtaagt aagaaattta
      601 gtaagtgaga agttcagtaa taagttgtag taaatgaaaa gtttaggaag taggaagttc
      661 agtaataagt tgtagtaaat aaaaaattta ggaagtagga tttactgaaa tacaaatatt
      721 taaaatcaaa gagtttaaaa gaaaggagag ctactggaca agtatccaaa atagatagct
      781 gagtacaaaa tatctcataa aattaagcaa tataatacaa gagaattttg acattattta
      841 tatatattta ccgtgtacaa atagctaaat ttaggattaa gattgaaaaa tatcttataa
      901 gtctgagctt atataaatcc gtataagatg tatttaatcg aaaaatttta ttatggatat
      961 tgcttgtcta tattctgagt agcaaggttt tatcatgact ataaaaaagt tgccacaatc
     1021 agaattaaag ataatgaaat ttatatggaa atcagattcc aaagtaacat ctagagatat
     1081 tgttttagga atggagcaaa aatatcaatg gaaacaaacg acaactttga ctcttttatc
     1141 tagattagta gtaaaaagat ttctaaattc tcaaaagata gataaatata cacattatga
     1201 agttttaatt aaagaaaagg aatacatagg agttgagaca agagattttt ttagaaatat
     1261 tcatgattct tctataaaaa gtttattgtt gtcattacat gaaaatatta atttgagcaa
     1321 agatgatatc ttacttattg aagagtggat aaaaaatcta aaagaagagg agaaagacgt
     1381 ataagcaaac gtatttctta tagcattaat ataaagtgta tgtaagtgta tttatgtaat
     1441 atattagtct acttaagtaa tatgacaaat gattataagt ggattatgat actataatgt
     1501 gaatctaaat aaattaaata taaattgata gtggatattc tatttaatta aatttaaaaa
     1561 gctaccttta cttataagta taattaaggt agctttttaa atagaggtag tgtgattaaa
     1621 gagaattttt aaatataaat tgtgaagctt taatatagat gacaatatat attttgcaaa
     1681 tatgacacag tgttttcgta tttaagatga taaaataaat aggaattaat gaagatattt
     1741 aaaaaataaa aataaagaat taatagaaga tattaaagag atagagataa aagtgttaat
     1801 agaagatatt gaaaaagtaa aaataaagga ttaatagaag atactgaaga ggtagaaaca
     1861 aaagtgttaa tagaagatat tgaaaaaata aaaacaaaag attaataaaa ggtactgaag
     1921 agatagagat aaaagtgtta atagaagata ttgaaaaata aaaataaaag attgatataa
     1981 tatactgaag aggtagaaac aaaagtgtta atagaagata ctaaaaaagt aaaaataaag
     2041 gactaataaa aggtactgaa gagatagaga aaaaaatgtt aatagaagat actgaaaaaa
     2101 tagaaataaa aaattaggag gaaaatttat gaaatatcag gtttcattat tagcagtgaa
     2161 ggatattgaa gtatcaaaaa aattttacaa agaattattt gagcaagaaa ttgaattgga
     2221 cttaggcaaa aatgtaacat ttaaaggagg atttgctata caagaagact tcgcatggct
     2281 tacagggatt aatccagata caattataca aaaatcaaat aatatggaac tttattttga
     2341 ggttgatgat tttgacgaat ttattgaaaa actcaattat tataaagatg tagagtttgt
     2401 ccataagcca ctaaaacatg aatggcaaca aagagtagtg cgtatttatg acccagataa
     2461 gcatattatt gagataggag agtctatgga agttatagct agaagatatt tatctgaggg
     2521 atactctgta gaagaaactt ctaaaataat tcaacatcca attgaatttg taaagcagtg
     2581 tgaaaatagt aaggaatgat tgtttaaatt ataattattt agtagaaatt aattgtagtg
     2641 gaactaattc aagataatat ataggactag tatttgacaa atgtcataaa ttaaattaaa
     2701 ataaagaaaa tattaataaa gaaaaataag gggaatatta ataaagaaaa aataaatata
     2761 ata
//
LOCUS       DAMJYN010000196         2743 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.202, whole genome shotgun sequence.
ACCESSION   DAMJYN010000196 DAMJYN010000000
VERSION     DAMJYN010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2743)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2743)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2743
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.202"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            394..2205
                     /locus_tag="PC466_003699"
     CDS             394..2205
                     /locus_tag="PC466_003699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HDF2771044.1"
                     /translation="MKKKYDFLIYSAIWLVIIIFFIFSLYHSIEHIKIISHTGTIRSE
                     TQKVVKQELNNERNDDLIKRLDNILIKLRTGNGENGFQRCDNKEFQQKLNQMDSMWES
                     MKKEIIKVRNGASGDKLYKLSEEYSVLSNQIVFISEKHSNAKLYSFATALFIYLIFST
                     ISLLIWEYYNKKRFKRIFYTDNLTKIKNQVAFENRAIEILYNASNKEYVLLNIDIDNF
                     KYINDTHGYEYGDKVLIIVAAALSKTFNIKETCARIGSDNFVILAKYRDSLLEDIREM
                     LTNAIISELDMNVTQTISYCIGAYLVEIDNLGYKSINSIMDKANIAHKVSKTRGISST
                     VWYNENLLKQLQMENSIYNYMYKAIENEEFHMYLQPKFQISSLNVVSAEALVRWFSPE
                     LGFLSPDEFIPLFEKSGFIIELDFYMLKKACSFVKKTFMKKNQYTYPIAVNFSRVTIY
                     QNSFYQRFLDTVKEYEIPFKYIEIEVTESAFNEISQPVISILEELKKLGFLISMDDFG
                     SGYSSLSLLCSLSINGLKLDKSLLKETFNREKVYSIIQCIIEMSHRIGMSVVCEGIET
                     KKDLEFLNTVKCDVGQGFYFSKPIEEKEFFNKYVTKK"
     gene            complement(2293..>2743)
                     /locus_tag="PC466_003700"
     CDS             complement(2293..>2743)
                     /locus_tag="PC466_003700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2771045.1"
                     /translation="TNYYMEFEDIPEYYEVNFNNYLYIITRFSFIPDGTEIFFTWEEI
                     HYWDEKVATEKTFINGETLVDSYNFPNNEVKDYIQKRESLYIETKKYYEEKGLKIERH
                     ALGSEDGEYVELTNDSILYLLDIEAVEIREQSKNIEEFLYKYKKRFK"
BASE COUNT         1039 a          280 c          404 g         1020 t
ORIGIN      
        1 ataaaataaa ttcaaagagt taaattgtag gtaaatagta ttttaattat ttattaaaat
       61 atagattatg tatatgccaa atttaaaaag agacataaag acattataca aatatattat
      121 tggggtgata ttttataaga aaagaagtga tgcagtaaat taattgagca atttaaaaat
      181 gatttaatga tagtgttgat gaatgtttaa aaagaaattt tagaaaaacg tatattgctg
      241 tttgtgttgg aggtgatgaa tttgtataat ttatagggta taaatgatta aactacttaa
      301 gataaataca tatcactgta aaatattgat aatcattttt tataagagat tgattatttg
      361 caaattatat atattacaaa tgaggtaaca ataatgaaga aaaaatatga ttttttaatt
      421 tattctgcta tttggctagt tattattatt ttttttatat tttctctata tcatagtata
      481 gagcatatta aaattataag tcacactggt actattcgca gtgaaactca aaaggttgtt
      541 aagcaagaat tgaataatga aagaaatgat gacttgataa aacgactgga taatattctg
      601 ataaagctaa gaacaggtaa tggagaaaat ggatttcaaa gatgtgataa taaagaattt
      661 caacaaaaac taaatcaaat ggattctatg tgggaatcta tgaagaaaga aattataaaa
      721 gttagaaatg gtgcttcagg tgataaatta tataaattga gtgaagagta ttctgtgttg
      781 tctaatcaaa ttgtttttat atctgaaaaa cactctaatg caaaattgta ttcttttgct
      841 actgcactat ttatttatct tatattctca acaataagtc ttttaatttg ggaatattat
      901 aataaaaaaa ggtttaaaag aatattttat actgataatt taacaaaaat aaaaaatcag
      961 gttgcatttg aaaacagagc gattgaaatt ttgtacaatg catctaacaa agagtatgta
     1021 ctgctaaata ttgatattga caattttaaa tatattaatg atacacatgg atatgaatat
     1081 ggagataaag ttctaataat agttgcagct gcactttcta aaacttttaa tatcaaagaa
     1141 acttgtgcaa gaattggttc agataatttt gtaatacttg caaaatatag agattctctt
     1201 ttagaggata ttcgggaaat gctaactaat gctataatct ctgaattaga tatgaatgta
     1261 actcaaacta tatcttattg tataggagcg tacttagttg aaattgataa tttaggttat
     1321 aaatccatca attctataat ggataaggca aatattgcac acaaggtaag taaaacaaga
     1381 ggaatttcct ccacagtatg gtataatgaa aatctgttaa aacagttaca aatggaaaat
     1441 agtatttata attatatgta taaagcgata gaaaatgaag aatttcatat gtatttgcaa
     1501 cctaaatttc aaatatcttc tttaaatgtt gtaagcgcag aagctcttgt aagatggttt
     1561 tctccagaac ttggtttttt atcaccagat gaatttattc cattgtttga aaaaagtgga
     1621 tttattattg aattggactt ttatatgtta aaaaaagcgt gttcatttgt aaaaaaaacg
     1681 tttatgaaaa aaaatcaata tacatatccg attgcagtta atttttcaag ggttactatt
     1741 taccaaaata gcttttatca aaggttttta gatactgtta aagaatatga aattcctttt
     1801 aagtatatag agatagaggt aactgaaagt gcttttaatg aaatatctca accagttatt
     1861 tcgattttag aggagcttaa aaagttagga tttttaattt cgatggatga ttttggatca
     1921 ggatactctt cattaagtct tttatgttct ctatctatta atggattgaa gttagataaa
     1981 agcttactta aagaaacatt taaccgggag aaagtatata gtattattca gtgtattatt
     2041 gaaatgtcac atcgtatagg catgtctgtt gtatgtgaag gtattgaaac taaaaaagac
     2101 ttggaatttt taaatacagt taaatgtgat gtaggacaag ggttttattt ctctaaaccg
     2161 atagaagaaa aagaattttt taacaaatat gtaactaaaa aataatataa ttatttttat
     2221 cagtctatac attgagtcat tttatatttc gttaaatgac tcaatgtatt gttatgtatt
     2281 ttaaaatata aattatttaa aacgtttttt gtacttatat agaaattctt ctatattttt
     2341 tgattgttct cttatttcaa ctgcttctat atctagtaaa taaagtatag aatcatttgt
     2401 aagttcaaca tattcaccat cttctgaacc gagtgcatgt ctctcaattt ttaatccttt
     2461 ttcttcataa tatttttttg tttctatata taatgattct cgcttttgta tgtagtcttt
     2521 cacttcatta tttggaaagt tatatgaatc cactaatgtt tcgccattta taaaagtttt
     2581 ctcggtagca actttttcat cccaataatg gatttcttcc caagtaaaaa atatctcagt
     2641 tccatctgga atgaatgaaa acctggtaat aatatataaa taattattga aatttacttc
     2701 ataatattca ggaatatctt caaattccat atagtaattt gta
//
LOCUS       DAMJYN010000197         2610 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.203, whole genome shotgun sequence.
ACCESSION   DAMJYN010000197 DAMJYN010000000
VERSION     DAMJYN010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2610)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2610)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2610
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.203"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            239..862
                     /locus_tag="PC466_003701"
     CDS             239..862
                     /locus_tag="PC466_003701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002467475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2771046.1"
                     /translation="MANTKTQKILSISKTKSENIAEWFVSDAQWKLLAEHLELGKTAI
                     FKYKKLIKIKTEEKDALYALGDIFTLNQLNTVIELFNDAIEHPEKYKKPKKKSDVDLK
                     AQADVIQKHTKDMNMDYLGYQGKPTARKEKAEIETENKTDKRAQIPDKSEVIAKHNAE
                     RKAMKEEIEALPKDSQERIEKERAYKQSEGDRIAEFWDAQKREQEDK"
     gene            875..1303
                     /locus_tag="PC466_003702"
     CDS             875..1303
                     /locus_tag="PC466_003702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002467478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HDF2771047.1"
                     /translation="MAKVWRYTIKLPPMGTPRPRTRRLDDGRTITYYDQSYSDYLDAI
                     QAELAKDNAINDDFYDVINTELGVKAEIMFYVQAPRSQKRIKKLTRTTAPDIDNLLKA
                     ALDGIFRGLEVKDSRVALVSMGKFQEMENPRTEIVLRGIE"
     gene            1303..2268
                     /locus_tag="PC466_003703"
     CDS             1303..2268
                     /locus_tag="PC466_003703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002467482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2771048.1"
                     /translation="MANTNLDKFLVIEQMMDEAQGLMEPYLSSLEQRYEYMNVLRKEY
                     SNLSHTLGKIQQRVIKQGDKLEVDADVKNVAQSARDRIDEHIEAIEEDKADGDNQPSV
                     KQLKRAREKLDGELDEDSIGEAWRLLKVRKIEIEELNVLMDLIDAMEDGKQDKAESIV
                     KKIEKLRSDYTSGFVRYREALEQGEDVQKEVDNVIGDLEDSGYIQEAESLTDARPSIA
                     EERGLRPDAQPLLDLLNPIKSAGLEYFQSRNRNSASYDLNVAFAKEVAYTRRALLEDR
                     EYIGTRNAFNRLNTAFEELSGYMYDRFYQLGGTPVNYHGHDDRVR"
BASE COUNT         1089 a          359 c          548 g          614 t
ORIGIN      
        1 gaagtattca taactgtaag tataagtata aataattatg taaatagaga tattaatatg
       61 ataataagta aaatagtaaa taggataata aataagcaat atatgtccct aatcataact
      121 atagagcaaa gttggttgtt tacttataaa cgtaaataag aacgcaaata aagacgtaag
      181 taaagatata agtattaagt taaataatta aaattaatga ttaaaggagc gttttaatat
      241 ggctaacact aaaacacaga agatattaag tatctcaaaa acaaaaagtg agaatatcgc
      301 agaatggttt gtcagtgacg cacagtggaa attattagct gaacatttag agttaggtaa
      361 aacagctatc ttcaaatata agaaactaat caagatcaaa actgaagaaa aggacgcact
      421 ttatgcgtta ggagatatct tcacgttgaa tcaactaaac actgtcattg agctatttaa
      481 cgacgctata gaacaccctg aaaagtataa aaaaccgaag aaaaaatctg acgtcgattt
      541 aaaagcacag gctgatgtca ttcaaaaaca tacgaaagat atgaatatgg attatttagg
      601 ttatcaaggt aagccgacgg caaggaaaga gaaagccgaa atagaaactg aaaacaaaac
      661 agataaacgg gctcaaatcc ctgacaaatc agaagttatc gctaaacata atgctgagcg
      721 taaagcgatg aaagaagaaa tagaagcttt gcctaaagat agccaagaac gaatagaaaa
      781 agaacgagcg tataagcaat cagaaggcga tagaatcgct gaattttggg acgcacaaaa
      841 gcgagaacag gaagataagt aggagtgaat agcgatggct aaggtatgga gatacacaat
      901 caagttacca cctatgggga caccgagacc tcgtacaaga cgtttagatg atggacgtac
      961 tatcacgtat tatgaccagt cttatagtga ttatttagac gcaatacaag ccgaactagc
     1021 gaaagataat gcgattaatg atgattttta tgacgtgata aataccgagt taggcgtgaa
     1081 agctgaaatc atgttttacg tacaagcgcc aagaagtcaa aagcgaataa aaaagctaac
     1141 aaggacgaca gcacctgata tagataactt gctcaaagca gcattagacg gcatcttcag
     1201 aggattagaa gtcaaagaca gccgagtagc attggtatca atgggcaagt ttcaagaaat
     1261 ggaaaatcca agaactgaga tagttttaag ggggattgag taatggcgaa cacaaattta
     1321 gataagtttc tagtgataga acaaatgatg gacgaggcac agggattaat ggagccgtat
     1381 ttaagcagtt tagagcaacg ttatgagtat atgaatgtgt tgagaaaaga atatagtaat
     1441 ctatcgcata cactaggcaa gatacagcaa cgtgtaatca agcaaggtga taagctcgaa
     1501 gtagacgcag acgtaaagaa tgtagcacaa agtgcaagag accgaataga cgagcatata
     1561 gaggcgatag aagaagataa agcagatgga gataatcaac catcggttaa gcaattaaaa
     1621 cgtgctagag aaaagttaga cggcgaatta gacgaagaca gcataggaga agcatggcga
     1681 ttgttgaaag ttcgaaaaat agaaatcgaa gagttaaatg tgcttatgga cttaatcgac
     1741 gctatggaag acggtaaaca agataaagca gagagtattg ttaaaaagat tgaaaagcta
     1801 agaagtgatt atacaagtgg ctttgtacgc tatagagaag cattagagca aggagaagac
     1861 gtacaaaaag aagttgataa tgttatcggc gatttagaag atagtggcta tatacaagag
     1921 gctgagagcc ttacagacgc aagacctagt attgcagaag aaagaggatt aagacctgac
     1981 gcacaaccgc ttctagacct tttaaaccct attaagagtg caggtttaga gtattttcaa
     2041 agtagaaata ggaactcagc atcatatgat ttaaacgttg cgtttgcgaa agaagttgct
     2101 tatacaagaa gagcgttatt agaagaccgt gaatatatcg gtactagaaa cgcatttaac
     2161 cgtttaaata cggcgtttga ggagctttca ggctatatgt acgaccgttt ttatcaacta
     2221 ggaggcacac cagtaaatta tcacggacat gatgatagag ttagataaaa aataaaagca
     2281 gcaaccaagc accatattaa ttatggtgct ttttataatg ccgtcatatc aaggttttaa
     2341 agacatttat aaccataatc aagcaataaa aataaaagtt cgctaaaacg aactgtaaaa
     2401 tacaataacc tttaaaaagg tataactaat taaatatatc attaaataag tagataagta
     2461 aacagtaata ataaaaatta aaaggaaatt aagcgatata cagagtatat aatcaaataa
     2521 agaacaatat aaaattagag gtagaaataa aataaatata agttcacgaa agtgaaccga
     2581 aaaggaacga gtataaaatt cagttcgcaa
//
LOCUS       DAMJYN010000198         2598 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.204, whole genome shotgun sequence.
ACCESSION   DAMJYN010000198 DAMJYN010000000
VERSION     DAMJYN010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2598)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2598)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2598
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.204"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(868..1905)
                     /locus_tag="PC466_003704"
     CDS             complement(868..1905)
                     /locus_tag="PC466_003704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF2771049.1"
                     /translation="MIKSKKILSLIIAGVLGVSMLTGCSQNDGSNASNENKKTDSKKQ
                     KNIGISQLVEHPSLDKAKKGFIKALEDKGYKDGDNIKIDFQNAQNDMPTTQSIASKFV
                     SDKKDLIYAISTPSAQAAYNATKDIPIIMTAVTDPVEAGLVKSLEKPGGNVSGTSDYL
                     SIDKTLELVKTLTPKAKKIGVIYNTSEVNSKIQVDSLHDYAKKNNYEVVEKGISTSSE
                     VNQAISSLVGKIDVLYVPTDNLIVSSMPIVSKVANENKIPIIASEEGSVSSGALACCG
                     IDYEKLGYKAGELAIEVLEGKSVGDIPVTTLDETEIIINEDTLKALDMQKLSADNIKY
                     IKSDENAKSAK"
     gene            complement(2002..>2598)
                     /locus_tag="PC466_003705"
     CDS             complement(2002..>2598)
                     /locus_tag="PC466_003705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003399531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF2771050.1"
                     /translation="GLIKESSGQITLDSTTITNLAEYKRTQIVSRVFQDPSLGTCPSM
                     TVRENLSLALNKGKLLNLKKCLRHKTNNLEHLLEGISLDLKKYLDIKVQYLSGGQRQS
                     LSLIMSSLASPKVLLLDEHTAALDPKTSNEVIELTDKIVREKNITTLMVTHNLKHALQ
                     YGDRLIMLHKGEVVLDVKDKEKENLTVEEILEKFEYAV"
BASE COUNT          861 a          391 c          329 g         1017 t
ORIGIN      
        1 cccagtgcca taatcgataa aattaaactt tgcgtcatta cagatataat acctgacata
       61 aataaaacac tcctttgaaa atatttttat aattttaatt atttgctaat tttgtgtata
      121 aaaaaaccac atagtgtaca aaactatgtg gtaaaaacac gaataagcca catagtttaa
      181 tctatgtggc tcttatatag ttaaatgaaa actttataaa caatatagcc aacatagata
      241 caatcccaaa attttaatag tcttaagggg tctgtatcta tgttaaaacg taggtacaaa
      301 ccctaaaaat agtggctata ataataataa tattttctat tgtttaataa agtattcata
      361 attatctctc ccttttaata ttttaattag tcagaaaatt atatgtattc tcgacttgtt
      421 ataaattata aattatacaa taataaaagt caactgctaa atttaattaa aatactaaat
      481 aatgtatact cagaatactt ttaaattaat gtattgtttg caaaaaacgt tatcctaagt
      541 tataagtgaa tgtggaaatt ttatcaaaat atttactaaa tatggaataa ctagacatgt
      601 atatcaatca aatatcataa aaaaaagctg tctggagaat attaaaattc ttttggacag
      661 ctcaagtagt gattagaaag ttatataact ttcataatca gtcgtcaata tagacgactt
      721 ttatggaaaa tgaataactt tatatgcaat attcaaattg ctacaataag cacaattttc
      781 aaagggttag ggtggataag agtacttatt atataaagtt ttcatattac ctacttcata
      841 ttacctattt tttgaaatta ataagtttta ttttgcagat tttgcatttt catctgactt
      901 tatatacttt atattatctg ctgataactt ttgcatgtca agtgctttta gtgtatcttc
      961 gttaattatt atttcagttt catctaatgt agtaactggt atatcgccaa cagattttcc
     1021 ttctaatact tcaatagcaa gttctccagc cttataacct agtttttcat aatctattcc
     1081 acaacaagct aaagcaccag aagatacaga accttcttca gaggctatta taggaatctt
     1141 gttttcatta gcaactttag aaactattgg catagaagaa actattaaat tgtcagtagg
     1201 gacatataaa acatctattt tgccaactaa actagaaata gcttggttaa cttcacttga
     1261 agtgctgatt cctttttcaa ctacttcata attatttttc ttagcataat catgtagaga
     1321 atcaacctgg atttttgaat taacttcact agtattgtat ataaccccta ttttctttgc
     1381 ttttggagtc aatgttttaa ccaattctaa tgttttatca attgaaagat aatcagatgt
     1441 accagaaaca tttccacctg gtttttcaag agatttaaca agtccagctt ctacagggtc
     1501 tgtaacagca gtcattatta ttggaatatc tttagtagca ttataagctg cttgtgcaga
     1561 tggagtagat atagcatata tcaaatcttt tttgtcggat acaaacttac tagcaatact
     1621 ttgtgtagta ggcatatcat tttgtgcatt ttggaaatct atttttatat tatctccatc
     1681 tttatagcct ttatcttcga gtgctttgat gaatcctttc tttgctttat ccagagacgg
     1741 atgttccact aattgactaa tacctatatt tttttgtttt ttgctatctg tttttttatt
     1801 ttcatttgaa gcattggagc catcattttg agaacatcca gtaagcattg atacaccaag
     1861 tactcctgct ataattaaac ttaatatttt tttacttttt atcattttat tttcctccct
     1921 taaaatttaa taattatatt tgttcatata ttcatatgat agattataaa tatttctgat
     1981 taaaactaag attttaattt cttatactgc atattcaaat ttttctaaga tttcttcaac
     2041 tgttaaattt tctttttctt tatcttttac atctaataca acttcaccct tatgaagcat
     2101 tatcaaccta tctccatatt gaagagcgtg tttcaagttg tgagtaacca taagtgtagt
     2161 tatatttttt tctcttacga ttttatctgt taactctatt acttcatttg atgtttttgg
     2221 gtcaagtgct gctgtatgtt cgtctagtaa taagacctta ggacttgcta agctagacat
     2281 aattagtgat agtgattgtc tttgacctcc tgaaagatat tgtactttaa tatctaaata
     2341 tttttttaag tccaaagaaa ttccttcaag taagtgttcc aaattattcg ttttatgacg
     2401 aagacatttt tttaagttca ataatttccc tttattaagt gctagagata aattttctct
     2461 aaccgtcata gaaggacaag ttccaaggct tgggtcttga aaaactctac ttactatttg
     2521 agttctttta tactcagcta aatttgttat agtagtacta tctaaagtaa tttgaccaga
     2581 agattctttt ataagccc
//
LOCUS       DAMJYN010000199         2589 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.205, whole genome shotgun sequence.
ACCESSION   DAMJYN010000199 DAMJYN010000000
VERSION     DAMJYN010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2589)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2589)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2589
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.205"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            469..948
                     /locus_tag="PC466_003706"
     CDS             469..948
                     /locus_tag="PC466_003706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDF2771051.1"
                     /translation="MDKTTFTNNILESEQTLYRVSKSILGNDQDCEDAVNNAILKAYE
                     KLDSLKEEQYFKTWLIRIVINECNSLRRKRLKSLSFEDVFKNKKIDEKDDYSDLYTAI
                     QSLPKKIKIPIVLYYIEGYSVDEVKEILDIPQGTVKSRLSRGRTLLKTKLENTEVII"
     gene            945..1724
                     /locus_tag="PC466_003707"
     CDS             945..1724
                     /locus_tag="PC466_003707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2771052.1"
                     /translation="MNKNILNNSFPEVPESFHNSLSKTLNSLPEREENYKMINNKTHK
                     LPFRKGLVATLAITLILSTTALAVGHIYSLVGKSSTKATYTSIPTTEQVKKDFNFTPN
                     IVSEFSNGYKFKGAYTVNKKALDKENNVLGKSKALSFEYKNGNDEISLDTANNVLEKS
                     SDNLKVVDTYKDINISYEAFAQKFVPEGYKMTEQDKIDEKSGKYTFSVGPNNESDKVE
                     VNEFKFLTWKQDGVYYSFTVQDSNLSMNDLVKMAHEVIDAK"
     gene            complement(1974..2474)
                     /locus_tag="PC466_003708"
     CDS             complement(1974..2474)
                     /locus_tag="PC466_003708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2771053.1"
                     /translation="MIEGIKFIKAEEKYIYSYWQTFDKIAKERKYLAMDEAFPFEETV
                     EFIKNTINKNLPQLFIIDLESDNCIGWCDVLPKTEKVGYLGMGILKEYREKGIGSSLL
                     KQIIDLSKEYGYEKIELDVFKSNSRAIHVYKSLGFVEVNTISSGFTWNDRPVKEEVIQ
                     MELTLI"
BASE COUNT         1016 a          353 c          316 g          904 t
ORIGIN      
        1 tatgttcata tctatctaaa ataatgacat ttctaactct tgattctcat ttaagtttca
       61 ttgttttttc ttaaaagcct acttttagtc aaaataccgt tatctttagt cattaattaa
      121 aaaacttatt ttaaatctat acatgaagta aataatccaa aagcattatt ttctaactac
      181 tcaacatcaa atacttacta ttttataatt acttaatata aacacttact ataaaactaa
      241 atatataaat ggcttctaaa gtttaatata tctacatggc tttatatatg aggggaaaat
      301 actagaaaaa aatatattat agaatatttg tatagaatag gcaaaacttt caaacttaaa
      361 tttatcaaat aatcataaaa aaagtgaacc atctatagta aaattttatc taataagtga
      421 aaggcaaaaa agtagcgcta cgatttgcat agaagggaag gaactcagtt ggataaaact
      481 acatttacaa acaatatact tgaatcagaa cagactttgt atcgagtatc taagtctatt
      541 ctaggaaacg accaagactg tgaagatgcc gtcaacaatg ctattttaaa agcatatgaa
      601 aagttggatt ctcttaagga agaacaatac tttaaaacat ggctgattag aatagtcata
      661 aatgaatgta attcattaag acgcaaacga ttaaaatctc tatcatttga agatgtcttc
      721 aaaaacaaaa aaattgatga aaaagatgac tatagcgatt tgtatactgc tattcaaagt
      781 ctacctaaaa aaattaaaat tccaatagtc ctttactata ttgaaggtta ttcagtagat
      841 gaggttaagg aaatattaga tatacctcaa ggaactgtaa aaagtagatt atcaagagga
      901 agaacattat taaaaactaa attagaaaac acggaggtaa tcatatgaat aaaaatatat
      961 taaataattc gtttccagaa gttccagaaa gttttcataa tagtttaagt aaaacactaa
     1021 atagtttacc agaaagagag gaaaattata aaatgattaa taataaaaca cacaaattac
     1081 catttagaaa aggcttagtt gcaactttag ccattacttt gatattgagc acaacagccc
     1141 ttgcagtagg acatatatat agtttagttg gaaaatcaag tactaaggct acctatacat
     1201 ctatcccaac tacagaacaa gtaaaaaaag actttaactt tacccctaat atagtttctg
     1261 aatttagtaa tggatataaa tttaaaggag catatactgt aaataaaaaa gcacttgaca
     1321 aagaaaataa tgttttagga aaatcaaaag cacttagttt tgaatataaa aatggcaatg
     1381 atgaaatatc tcttgacaca gcaaataatg tacttgagaa gagttctgac aatctaaaag
     1441 ttgtagatac ttacaaagat attaatattt cttatgaagc attcgcacaa aagtttgtac
     1501 cagaaggtta taaaatgaca gaacaggata aaattgatga aaaatcaggc aaatacacat
     1561 ttagtgtagg gccaaataat gaatcagaca aagttgaagt taatgaattt aagtttttga
     1621 catggaaaca agatggagtt tactattctt ttacagttca agactcaaat ttatctatga
     1681 atgacttagt taaaatggct catgaagtaa tagatgcaaa ataaacataa gtaataataa
     1741 gttgtttatg agtttattat ttatgacttt aattttttta ttagtaaaca tggttgtatc
     1801 ttccatcttt atattttctt taaatttaat atataaaatt ttagatattt agctaccttc
     1861 aaaagaacca ttattaaaaa gcccttaaaa atatttcttt tatatggaat tttaagggct
     1921 ttaactttat tttatacaag tgtatatgga attttaaaga ctttaacttt attttatata
     1981 agtgtaagct ccatttgaat tacttcttct tttacaggtc tatcattcca tgtaaaacca
     2041 ctagatattg tatttacctc tacaaaccct aaagatttat aaacatgaat agctctacta
     2101 ttacttttaa atacatcaag ctcaattttt tcatacccat attcttttga taaatcaata
     2161 atttgtttta aaagactact tccgatacct ttttccctat actctttaag aatacccatg
     2221 cctaaataac caactttttc agttttaggt aaaacgtcac accaaccaat acagttatct
     2281 gattctaaat caattataaa cagttgtggt aagtttttat ttatagtatt ttttataaat
     2341 tcaactgttt cttcaaaagg aaaggcttca tccatagcta gatatttcct ctcttttgct
     2401 attttatcaa aagtttgcca atacgaataa atatactttt cttctgcctt tataaatttt
     2461 attccttcta tcaacttaac atttctcctt tttaatttat gattgtagtt aacttatttt
     2521 atatgattct agtttataat gctatataaa ttactatata ttagcttaaa atatctttgt
     2581 atatttcta
//
LOCUS       DAMJYN010000200         2581 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.206, whole genome shotgun sequence.
ACCESSION   DAMJYN010000200 DAMJYN010000000
VERSION     DAMJYN010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2581)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2581)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2581
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.206"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(145..1725)
                     /locus_tag="PC466_003709"
     CDS             complement(145..1725)
                     /locus_tag="PC466_003709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional ADP-dependent NAD(P)H-hydrate
                     dehydratase/NAD(P)H-hydrate epimerase"
                     /protein_id="HDF2771054.1"
                     /translation="MLIGTSKLSRNVDTACVEEVGIPMIVLMENAVISAMKNMDIDMY
                     NSYTVVCGVGNNGGDGLGIARHLNTYGKEVNVFLVGNLEKLSECSKINYNVLLNMGIN
                     IININKNDLSEKNYGDENEVDKIIKVEKQNIIKNKNLTIFKDRVSKSDVVVDAIFGTG
                     LKRDITGIFKEVIDIVNDNSKNTYSIDIPSGIDSDNGNVLGTCIRANKTISFEFYKRG
                     FLNYDTSTLIGDVVVEKIGVPDFITRKYHDEEFITDKTFVKNNIRRRDKHGFKSDFGK
                     VSIVAGSKGFYGASFIATESAVKSGSGLVTLISSEDVQEKVSIRLTEAMTLNFEEERL
                     NKLLNSSDAIGFGPGMGDNSQTFDKLLKIVENSNCPIVLDADGLNVMKDRCYKFLEWK
                     NRFVITPHLGEMARLTGDSIGYIREHRVDVAKEFAQKYNLVVLLKGYQTVITDGKKTY
                     INPTGNSCMATGGMGDCLLGMITSFIGQGMDILEATVSGAYIHGYIGDKLSKAMYTVN
                     ATDLISNISLTMKELLDI"
BASE COUNT          863 a          443 c          247 g         1028 t
ORIGIN      
        1 gttagcttta ggggatttta gcaattcaag tagtattgga taggttctat cctatctcta
       61 catataggtt tccctatatg ctgactattt tagctactaa ctcatgacta aagtcacaag
      121 tgtgcgtagc tattttttaa tcaattatat atccaacaac tctttcattg ttaatgaaat
      181 gttacttatt aaatccgtag catttaccgt atacattgct ttgctcaatt tatctcctat
      241 atagccatgt atatatgctc cactaactgt agcttccaat atatccatac cttgacctat
      301 aaatgaagta atcattccaa gcaaacaatc acccattcca ccagttgcca tacagctatt
      361 tcctgtagga tttatatatg tttttttacc atctgttatg acagtttgat aaccttttaa
      421 aagcaccacc agattatatt tttgagcaaa ttcttttgca acatctactc tatgttctct
      481 tatataccca attgaatctc ctgtcaacct ggccatttct cccaaatgag gtgtaattac
      541 aaatctattt ttccattcta aaaacttata acatctgtcc ttcataacgt tcaatccatc
      601 tgcatctaat actattgggc aattagaatt ttctactatc ttaagtaatt tatcaaatgt
      661 ttgactatta tctcccatac ctggaccaaa accaattgca tcactagaat taagtaattt
      721 atttaatctt tcttcttcaa aatttaaagt cattgcttct gtaagtctaa tagatacctt
      781 ttcttgcaca tcttcactac taattaatgt tacaagtcca ctcccactct taacagcaga
      841 ttcagttgct atgaaacttg caccataaaa tccttttgaa cctgcaacta tagatacttt
      901 tccaaaatca cttttaaaac catgcttatc tcttcttcta atattatttt ttacaaaagt
      961 cttatcagtt atgaactctt catcatggta ttttcttgta ataaaatctg gaacacctat
     1021 cttttctaca actacatcac ctataagtgt gctagtgtca tagtttagaa aacctctttt
     1081 ataaaactca aagctaatcg ttttgtttgc tctaatacaa gttcctaata catttccatt
     1141 atcgctatct atacctgaag gaatatctat agaatatgta tttttgctat tatcgtttac
     1201 tatgtcaata acttctttaa aaataccagt tatatcacgt tttaatccag tcccaaatat
     1261 agcatctact acaacatcac ttttagatac tctatcttta aaaattgtta aatttttatt
     1321 ttttataata ttttgtttct caactttaat aattttatct acttcatttt catctccata
     1381 atttttttca cttaaatcat ttttattaat atttataata ttaattccca tatttaaaag
     1441 tacattgtaa tttattttag agcattcact tagtttttca agattaccta ctaaaaatac
     1501 gtttacttct tttccatatg tatttagatg tcttgctatt ccaagaccat ctcctccatt
     1561 atttccaaca ccacatacaa ctgtataact attatacatg tctatatcca tatttttcat
     1621 tgcagatata accgcatttt ccatcaatac aatcattgga atccctactt cttctacaca
     1681 tgcagtatca acatttctgc ttaatttaga tgtacctatt agcataaatt atcactccta
     1741 taaagttaaa gacttcttaa atacttacca aaaatatcta ttgaaatctt ttaatcccat
     1801 aaatatcata aataaaatca ctaaaactaa gagttttgaa ataatttaaa ataacaaaaa
     1861 attttgaatt aaaacaatta tttaatttat tataccatat aatttaagtt attatgttga
     1921 tttaaaacct atttacacta attatctaaa tatctcttta tttttataat cttttatgac
     1981 ttatttatat ttttcatttt tataaaaaaa caataattaa gaatataact atattctaca
     2041 tgtaaaaatt tttttattta aactcaattt tctgataact tgataatttt tcaaaattta
     2101 tagttgactt ttatttttta ctgtattaaa ctaattacta tacaaaacag aaaacaaaat
     2161 tttcaaaatt attaaattaa aaggagaggt aaatatgaag actttattaa acaaacaagt
     2221 acgatttttt agtagccaat ttagttaggg tttgtaccta agttaagaca aattgtcata
     2281 acatagatac aagcccctta ggattatgat ttttaaggat tgtatctatg ttggctatag
     2341 taattgttgt taaagttttt attttatcat cataatatag agccacatgg attatactgt
     2401 gtggcttatt cgaatttttg ccatacagtt atatatactg tgtggttttt ttatatcaaa
     2461 atcatttttt aaaaccaaat ttaaaaaacc atttaaaata ttttcaaagg ggtgttttat
     2521 ttatgtcagg tattatatct gtaatgacgc aaagtttaat tttatcgatt atggcactgg
     2581 g
//
LOCUS       DAMJYN010000201         2578 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.207, whole genome shotgun sequence.
ACCESSION   DAMJYN010000201 DAMJYN010000000
VERSION     DAMJYN010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2578)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2578)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2578
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.207"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(225..1475)
                     /locus_tag="PC466_003710"
     CDS             complement(225..1475)
                     /locus_tag="PC466_003710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1015 domain-containing protein"
                     /protein_id="HDF2771055.1"
                     /translation="MATIKPFKAIRPNKYIVDKVAALPYDVMNSKEARRIAEGNPYSF
                     LHIDKSEIDLDENIDLYDEKVYLKARENLYEFRKQEILVKDDKECIYIYKQIMDGRAQ
                     VGIVACISVDESLNGTIKKHEYTRPEKEIDRTKHIKYCDANTGTILVTYKHQRVIDDI
                     INDFMDNNEPLYDFITDDKIEHTVWKIDSDDIIDNLVDKFEKLDYLYIADGHHRTASA
                     ENVAKEMRAKNPNYTGKEEFNYFIAMIAPDENLMVLDYNRVIKDLNGLSEEEFINKIK
                     ENFELEEIEGKEKYKPDKKGTFGMYLGDKWYKMKANKNLLEIEDPVDSLDISILQDYV
                     IDAILGIDNPRVDKRIDFIGGIRGLEELEKRVNEDMKVAFAMYPTSIEDLIRVADANK
                     IMPAKSTWFEPKVRCGLFLHEINE"
     gene            complement(1507..2448)
                     /locus_tag="PC466_003711"
     CDS             complement(1507..2448)
                     /locus_tag="PC466_003711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-3-phosphoglycerate dehydrogenase"
                     /protein_id="HDF2771056.1"
                     /translation="MYNILVTDGIEKEAARKLRELDFNVIEQFYEKDVLGDKLKDVDV
                     LVVRSATKVTKDVIDKALEGKKLKLIVRGGVGLDNIDVKYAQANGIKVMNTPNASSIS
                     VAELTIGQLFVLARFINTANVTMRDGKWEKKKYKGTEINGKTLGLIGFGRIAKEVAKR
                     AELLGMNVIYTDIMGEAQGFNNYKFCDMEEVLENADFLSLHIPFDKNKGAVITEKEIN
                     KMKKGAYLINCARGGLVDEKDLLKALDEGKLSAAAIDVYEQEPTLNLDLVNHPRVSPT
                     PHIGASTVEAQERIGDEIVNVIQDFFLDFNNLIGVAL"
BASE COUNT          777 a          495 c          241 g         1065 t
ORIGIN      
        1 aatacatatt taaaacctta taaatataca aatacaatta tatgaatttt catcctcaat
       61 tatagcatag aatatgacta tctatatcct aaaattatcc atttctaaaa aaaggtaact
      121 attattaaga atatcaactt atagaattta tattccacat acgattttca atcaaaaaaa
      181 caagggctaa aaagtgaatt gtacactttt tagcccttta ttaattattc atttatttca
      241 tgtaagaata gcccacatct tactttaggt tcaaaccatg ttgacttagc tggcattatc
      301 ttatttgcat ctgctactct tattaaatct tcaatactag taggatacat tgcaaatgct
      361 actttcatat cttcattaac tcttttttct aattcttcaa gacctctaat tccaccgata
      421 aaatcaattc ttttatctac tctaggattg tcaattccta aaatagcatc aataacatag
      481 tcttgtaata tagaaatgtc taatgagtca acagggtctt ctatttctaa taaattttta
      541 tttgctttca ttttatacca cttatcacct aggtacattc cgaaagttcc ttttttgtca
      601 ggtttatatt tttcttttcc ttctatttct tctagttcaa aattttcttt tattttattt
      661 ataaattctt cctcgcttaa accatttaag tctttgataa ccctattata atccaaaacc
      721 attaaattct catctggtgc aatcattgct atgaagtaat taaattcttc tttgccagta
      781 taatttggat ttttagctct catttctttg gctacatttt ctgctgaagc tgtcctatga
      841 tgaccatctg caatgtatag ataatctaat ttttcaaatt tatctactag gttatctatt
      901 atatcatcac tatcaatctt ccatactgta tgctctatct tgtcatctgt tatgaaatca
      961 tataaaggtt cattattatc cataaaatca ttgattatat catctatcac cctttgatgt
     1021 ttgtaagtta caagtatagt tcccgtatta gcatcacagt attttatgtg tttagttcta
     1081 tcaatttcct tttctggtcg agtgtactca tgttttttta ttgttccatt caagctttca
     1141 tcaactgata tacatgctac tataccaact tgagctctac catccatgat ttgtttatat
     1201 atatatatac actctttgtc atcttttact agaatttctt gttttcgaaa ctcatataaa
     1261 ttttctcgcg cttttaaata aactttttca tcatataaat ctatattttc atctaaatca
     1321 atttctgatt tatctatatg caaaaatgaa tatggattcc cttctgcaat tcttctagct
     1381 tctttactat tcataacatc gtaaggaagt gctgctactt tatctactat atatttattt
     1441 ggtctaatcg ccttaaatgg tttaatcgtt gccattacta atttcctcct aattatacaa
     1501 aatattttat aatgctaccc ctattagatt gttgaagtca agaaagaaat cttgaatcac
     1561 atttactatt tcgtctccta ttctttcttg agcttctact gtagatgccc caatatgagg
     1621 tgtaggagaa actcttggat gatttactaa gtctaaattt aatgtaggtt cttgttcata
     1681 aacatctata gcagctgctg ataatttacc ttcatctaat gcttttagta aatctttttc
     1741 atcaactaaa ccgcctcttg cacagtttat taaataagcc cctttcttca tcttatttat
     1801 ttctttttca gttattactg cccccttatt cttatcaaat ggtatgtgta aagataagaa
     1861 atctgcattt tctaaaactt cttccatatc acagaattta taattgttaa aaccttgcgc
     1921 ctcacccatt atgtcagtat atataacatt catacctaat aattctgctc tctttgcaac
     1981 ttcttttgca attcttccaa aacctataag tccaagtgtc tttccattaa tttctgtacc
     2041 tttatacttc ttcttctccc attttccatc tctcatagtt acatttgcag tatttatgaa
     2101 tcttgcaaga acaaataatt gacctattgt aagctctgca acagatatac tgcttgcatt
     2161 tggagtattc ataactttta tgccattagc ttgagcatat ttaacatcta tattatccag
     2221 acctactcca cctcttacta tcaacttcaa ctttttaccc tctaatgctt tatctattac
     2281 atctttagta actttagtag ctgaacgtac tacaagtaca tcaacatctt taagtttatc
     2341 tcctaaaaca tctttttcat aaaactgctc tatcacatta aaatctaact ctctcaattt
     2401 tctcgctgct tctttctcta ttccatcagt aactaatata ttatacataa caaactcctc
     2461 caatttttat tcacttaatt tttccaattt ttatttttta aagtattttc atcaataaaa
     2521 aactttactt aatttaactt tctgtttata taattttcaa aatatttttt tattaaag
//
LOCUS       DAMJYN010000202         2556 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.208, whole genome shotgun sequence.
ACCESSION   DAMJYN010000202 DAMJYN010000000
VERSION     DAMJYN010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2556)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2556)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2556
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.208"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(184..1095)
                     /locus_tag="PC466_003712"
     CDS             complement(184..1095)
                     /locus_tag="PC466_003712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YafY family transcriptional regulator"
                     /protein_id="HDF2771057.1"
                     /translation="MSRAERLIELMITINAKRSFTAGELAEEFSVSKRTILRDLQVLE
                     SVGFPLYSKVGAAGGYHVLKERILPPITFSESEVKSIFFAYQSLEYYNDLPFEQETIS
                     VLKKFLNCIPNDIQYNIENMRRKLVFWTPDRHCSTPLLKELFNIVMNEFTIKIEYSSK
                     QKNSIRTIVPIGLYAMNGLWYCPAYCIKSESVKEFRADRIVKILSIENLSNKKYKVLS
                     SIHDYLKNMEVGTDYHIKINLTDEGVKRCETEFLLARGLKILSKGGYIDMYIPKSTLN
                     WVAEYFLTFGKNATIIEPIELKHLIKK"
     gene            1206..1673
                     /locus_tag="PC466_003713"
     CDS             1206..1673
                     /locus_tag="PC466_003713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2771058.1"
                     /translation="MENDTIKADDILNYCLSNLDDVVLMDSWGERAIYYNPNGVLKRG
                     VYVLTIKEKDSNHDKGSLVSRPNVYRVNIGLKKETFIEMFGYIPKRPGVGQIVDMDFD
                     FTKLDTIMPHPIYSWMGWICVLSPTEKTFENFKTLIEESYNFAKQKFKKRKNK"
     gene            complement(1841..2440)
                     /locus_tag="PC466_003714"
     CDS             complement(1841..2440)
                     /locus_tag="PC466_003714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2771059.1"
                     /translation="MKLKRTLFVGLALVLAIGITACARDNEKPNENAGKNPNESVNNN
                     EGYMNYYSTSYNDYIAGLNRYSIYDTPESINNQFKDKEYPGNEKYLSDVKAAYKDSRD
                     KIQSFVTSLKKDGKTEDTELKRMNDDLIAEGERLVKDIDERIEKLDKVSDEDMKKGQN
                     DFMKLVHGTEDVGNDIGSGFRKMIKDMNDRLGITGNNKK"
BASE COUNT          848 a          416 c          303 g          989 t
ORIGIN      
        1 tctactttcg taactttcac acttaggttt atttcatcct tatgttttag tttggttagc
       61 tttaggggtt tttagcaatt caagtagtat tggataggtg ttatcctatc tctacatata
      121 agtttcccta tatgctgact aatttagcta ctaactcatg actaaagtca caagtgtgcg
      181 tagctatttt ttaatcaaat gtttaagttc tataggttct attattgtag cattttttcc
      241 aaaagttaaa aaatattcag ccacccaatt aagtgtagat tttggtatat acatatctat
      301 gtatccaccc ttagacaaaa ttttcaatcc tcttgccaac aaaaattctg tttcacaacg
      361 ttttactccc tcatctgtca gattaatttt aatatgataa tctgtaccta cttccatatt
      421 cttaagataa tcatgtatag aagataaaac cttatatttc ttatttgata agttttctat
      481 actcaaaatc ttcacaattc tgtctgcacg aaattcctta acagattctg attttataca
      541 gtaagctgga caataccaaa gtccattcat agcatacaaa ccaataggaa caatggtacg
      601 tatactattt ttttgctttg atgaatattc aattttaatt gtaaattcat tcattactat
      661 attaaacaat tccttcaata atggtgttga gcaatgccta tctggtgtcc aaaaaacaag
      721 tttacgtctc atattctcaa tattatattg aatatcattt ggtatacaat ttaaaaattt
      781 ctttaaaaca gaaatagttt cttgctcaaa tggtaaatca ttataatact ctagtgactg
      841 atatgcaaag aatatagatt ttacctcact ctctgaaaat gtaattggtg gaagtatacg
      901 ttctttaagt acatgatatc ctccagccgc tccaactttt gaatatagtg gaaatccaac
      961 actttccaat acctgtaaat ctcttagtat agtacgtttt gatacagaaa attcttctgc
     1021 tagctctccc gctgtaaaac ttctttttgc atttattgtt atcatcagtt caattaaacg
     1081 ctcagctctt gacatattca tactcctaat ttaaatatag tgacaataat tgtcaccatt
     1141 atatgataag atattcttgc atctaaagca ataataatat taaagaaaga agggattgat
     1201 attttatgga aaatgatact attaaggctg atgatattct caattattgt ctatcaaact
     1261 tagatgatgt tgtactaatg gatagttggg gggaacgagc aatttactac aatcctaatg
     1321 gtgttttaaa gcgaggggta tatgttctta ccattaaaga aaaagacagt aatcatgata
     1381 aaggttcgtt ggttagtcgt ccaaatgtat accgtgtgaa tataggatta aaaaaagaaa
     1441 cttttattga aatgtttgga tatattccaa agcgtccagg tgtagggcaa atagttgata
     1501 tggattttga ttttacaaaa ttggacacaa tcatgccaca tcctatctac tcatggatgg
     1561 gatggatatg cgtcctaagc cctactgaaa agacatttga gaactttaaa actttaatag
     1621 aagaatctta caattttgca aaacaaaaat ttaaaaagag aaaaaacaag taaaaacata
     1681 aaaaaataac ctctaaataa actataatga aaatatgagg ttacaagata aaaattagta
     1741 tcttgataac atacaaaaaa gcgaagccaa aaaatatatt aattacaagg cttcgctata
     1801 tttcaaatat ttatttctaa ctttaaaact atttactcta ttatttttta ttatttcctg
     1861 ttattcccaa tctatcattc atatctttta tcatttttct aaaaccacta ccaatatcgt
     1921 ttccaacatc ttcagttcca tgaactagtt tcataaaatc attttgacct tttttcatat
     1981 cttcatcaga taccttatct aatttttcta ttctctcatc tatatctttt actaatcttt
     2041 ccccttcagc tattaggtca tcattcattc tctttaactc tgtatcttct gttttaccgt
     2101 cttttttaag agatgttaca aatgattgta ttttatctct actatcttta tatgcagcct
     2161 ttacatcact tagatatttt tcatttcctg gatattcttt atctttaaac tgattgttta
     2221 tactttctgg agtatcataa atagaatatc tatttagacc tgctatataa tcattataac
     2281 ttgttgaata ataattcata tatccttcat tattatttac agattcatta ggattttttc
     2341 ctgcattttc atttggtttt tcattatccc tagcacatgc agttattcct atagctaata
     2401 ctaatgctaa tcctacaaat aaagttcttt ttaatttcat ttttattacc ctcctagatg
     2461 ttttgtacta caaaaaattt taataatttt ctttcttaat ttagtatttc tatattttta
     2521 ttttttattt actaaaatta aacaagttat aattta
//
LOCUS       DAMJYN010000203         2538 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.209, whole genome shotgun sequence.
ACCESSION   DAMJYN010000203 DAMJYN010000000
VERSION     DAMJYN010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2538)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2538)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2538
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.209"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            647..1420
                     /locus_tag="PC466_003715"
     CDS             647..1420
                     /locus_tag="PC466_003715"
                     /inference="COORDINATES: protein motif:HMM:NF018933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDF2771060.1"
                     /translation="MTYANIRIDKIIEYIEKVATVKDFESMGLSKYIFNHLKDDPTYL
                     FRMQLSKVSKINAYMNTLESLEKRKSQPIQEKKSKSIYVDVVGIDLGSNNTITASDQS
                     MKRLFIKQNEHIKNAMITYEKTKNKRNSKAELNRAINKNTDKLINSLLNHYIEPVTYV
                     IGEMNQSSYAMTLFYKTFLHKLKRKQDINDISVYHVDESKTSITCPKCGYKDKKNRKN
                     NNRFECKECKFKCDNDDVVACVNIVKQYRVLTDEKVKQI"
     gene            1780..2046
                     /locus_tag="PC466_003716"
     CDS             1780..2046
                     /locus_tag="PC466_003716"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2771061.1"
                     /translation="MKYELTIKKGASFDDGSIIGNIFNTVSFKTYKVYQNEDKGLYFE
                     GQEQKYYLNNMMSEPDFNKVQDAILKFLFSKEDNNKDTLVEIEL"
     gene            2107..>2538
                     /locus_tag="PC466_003717"
     CDS             2107..>2538
                     /locus_tag="PC466_003717"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2771062.1"
                     /translation="MAYEKIKNMKIDIDNLKANITYASSNIHPIMYKKIELNQIIKNM
                     RSIEELHEEEKFLFPIIELVYNGEFKLQKTVSIKIRYAFMKIKNAIKNILNKNGEYEN
                     RLQYSKDPYNHIIEIKDIVHQFKQYYNIKDKRIKPTIIFIVG"
BASE COUNT         1051 a          256 c          415 g          816 t
ORIGIN      
        1 agtcaataga atacaataaa aagtttagtt ttttgtcctg ttgattgtgt acgtagtgta
       61 cgcttttagt gttagtctat ttatcaatag aataaacatg atgaatataa ctaaatttga
      121 tcgaaaacgt taaatctaga tatgttatac tttatttagc atcttcatgt tgttaattga
      181 aataggttat ttaattgtac agtacaggca ttaagttttt tgtaacttat gtttagagtt
      241 ctcactttca ttatgtatag ttaacttttt caatatgatg atagttttca gtctttttat
      301 gtcttaaggg tagctatata tgtagttacc cgattttata tttaaaacat tacacaggta
      361 taatgctacc tgtattcacc aagtaagatg agactttatt taaattgtct ttcataatac
      421 tctaatggcg taataactat tgtgaacatg gttaatagcc tatgcagtta cacctgcatg
      481 ggggattttt tgtgccatta tctaatttat gtatttatca ataggatgta ttatgtatat
      541 catttgtgtg taagtgtata acaaaagaaa ttgagataat cacttgtaaa atagctaata
      601 aatgggatgt gttagaaacc aatataatta agggggatat tataaaatga cttatgccaa
      661 tataagaata gataagatta tagaatatat tgaaaaagtt gcgacagtta aagattttga
      721 atcaatggga ttatctaagt atatatttaa ccatctcaag gatgacccta cttacctatt
      781 tagaatgcaa ctaagcaagg tatcaaaaat taatgcttat atgaatacgt tagaaagttt
      841 agagaagcgg aaatcacaac cgatacaaga gaaaaagagc aaatctattt atgttgatgt
      901 agtaggtatt gacctaggga gtaataacac gataaccgct tcagatcagt caatgaagcg
      961 attatttata aagcaaaatg aacatattaa aaatgctatg attacatacg aaaagaccaa
     1021 gaataagagg aattctaaag cagaactcaa cagagcgata aataaaaaca ccgataaatt
     1081 aattaatagc ttacttaatc attatataga gccagtaaca tatgtcattg gggaaatgaa
     1141 tcaaagtagt tatgcgatga ctttatttta taaaacattt ttacataagt taaagcgtaa
     1201 gcaagatatt aatgatataa gtgtttatca tgtagatgaa tcaaaaacat ctattacatg
     1261 cccgaagtgt ggatataaag acaaaaagaa caggaaaaat aataatagat ttgaatgtaa
     1321 agaatgcaaa tttaaatgtg ataatgatga cgtagtagct tgtgtgaata ttgtaaaaca
     1381 atatagagta ttaacggatg aaaaagtaaa acagatataa ataattgaat gcgatgttaa
     1441 agcagataaa ccataaagga aacggttaaa gcccaaagta aattatatac ttaaatattg
     1501 tgtacgtagt gtactaagac cacaatattt aagcaatcaa atatttagat atattgttgt
     1561 tcataattta tagttgatat gatattaata tcttgtgtac gtagtgtact ttcattatag
     1621 aaggatttaa aggacgctga gaaaaggtct tatttgcatt gagataagtt atgatggata
     1681 aatatattta aaaatagcga gaaaatgtca cgtaagtatt tacaaatagt ataaaaagaa
     1741 gtataataaa ggtaaatact taaggaaagg aagttgaaaa tgaaatacga attaactatt
     1801 aaaaaaggtg catcttttga tgatggaagt attatcggaa atatattcaa tacagtaagt
     1861 tttaagactt ataaagtata tcagaatgaa gataaaggat tatattttga aggacaggaa
     1921 cagaaatatt atttaaataa tatgatgtca gaaccagatt ttaataaggt tcaagatgca
     1981 atattaaagt ttttattttc aaaagaagat aataacaaag acacattagt agaaatagaa
     2041 ctataaaaat tttgtgtaca ttgtgtacgt tgtgtacata atgtacttaa attaggagtt
     2101 gttacaatgg catatgaaaa aataaaaaat atgaaaatag atatagataa tctaaaagca
     2161 aatattacct atgcaagtag taatattcac cctattatgt ataaaaaaat agaattaaat
     2221 caaataataa aaaatatgag aagtattgaa gaattacacg aagaagaaaa atttttgttc
     2281 ccaattatcg aactagtata taacggggaa tttaaattac aaaaaactgt atctattaag
     2341 atacgatatg catttatgaa gataaagaat gcgataaaga atatacttaa taaaaatggt
     2401 gagtatgaaa atagattaca atatagcaag gatccataca atcatattat agagataaaa
     2461 gatatagtac atcagtttaa acagtattat aatatcaaag ataaaagaat taagcccacc
     2521 attatattta ttgtaggc
//
LOCUS       DAMJYN010000204         2513 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.210, whole genome shotgun sequence.
ACCESSION   DAMJYN010000204 DAMJYN010000000
VERSION     DAMJYN010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2513)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2513)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2513
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.210"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            403..2298
                     /locus_tag="PC466_003718"
     CDS             403..2298
                     /locus_tag="PC466_003718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp8"
                     /protein_id="HDF2771063.1"
                     /translation="MLSNKKRSMAIVMAGATVMSAAAPIFADNTVTENVDKNYTVSAK
                     DSAKLIEEVRKALEVKFEDTKAGANVNDRVYDIKVDNVNLTNATQLQNKINSLTEGQS
                     LKVTIQDKGHQVLGGKVVDYKIENYKTAQEIVDAVNAYNATLAEDSDNKLTATIKSTN
                     TVEVKRAKDSANVITLNVGDQHLDFSKVITSEEGTFEGYEKSYSDIDSKELHTITVKN
                     ADLQDISAEELFDGIRLTTLGREIVNKVKNGYALTFENEAILTQEQEDSDDKDKPEKS
                     SFDIVLSKANEKSETISVSSKNHKLVRDLHKVLTDVKDGKELKVEVLSGDSRFTTAVE
                     VSKERFKDGEAEAIILVGEDAIVDGLASAPLASQKNAPILLSKKDSLPSEIEAEILRV
                     LGSNLSSKKIYIVGGESKVSKETEEKLSKLGVSKVERVSGEDRFETSLEIAKQLKDTF
                     KTAFVVGGNGEADAMSISARAAQFGAPIIVTGNELDANAEKLLKGKELEIVGGENSVS
                     KEVEDKLVDIDLNNKVERLAGENRKDTNAKVINKYYAGATKAYVAKDGYVGGNGQLVD
                     ALTAAPLAASSKAPIVLTTEELSKSQEEVVELRLKNATKLVQIGEGIAKNAIEKIAEK
                     INLFTKN"
BASE COUNT         1095 a          245 c          455 g          718 t
ORIGIN      
        1 tattagaata atttttaatt ttaaactcta atttatgatg attttataat atgttatata
       61 ttttaatata tggaggtaga tattaattta gtgatatata tttaagtaat aagagcaaag
      121 caaaaattag tgcatagtag tatataaaaa tggagtttga atacttttgt tagtatatga
      181 ttgtttagta gaaaatcact ataaaatagg gatttctatc tttgagcata attatagaga
      241 gctaagtagg gggaaggggt tcaagaagat attattagtg tttgtgttag taaattatgt
      301 aaacacataa aatatattga aaaataatat tatatataat attatttatg tgtgggaaat
      361 acgaatataa aaaataaaaa ataatattcg gaggacataa atatgttaag caacaaaaag
      421 agaagtatgg caatagtaat ggcaggtgct acagttatga gtgcagcagc accaatattc
      481 gcagacaata ctgtgacaga aaatgttgat aaaaattaca cagtaagtgc gaaagattct
      541 gctaaactaa tcgaagaggt tagaaaagca ttagaagtta agtttgaaga tacaaaagca
      601 ggagcaaatg taaatgatag agtttacgat ataaaagtag acaatgtaaa cttaactaat
      661 gcaactcaat tacaaaataa aataaactct ttaacagaag ggcaaagttt aaaagttact
      721 attcaagata aaggacatca agtgttaggt ggaaaagtag ttgactataa aattgaaaac
      781 tacaaaactg ctcaagaaat agtagatgca gttaatgctt acaatgcaac tttagcagaa
      841 gattctgata acaagttaac agcaactata aaatctacaa atacagttga agtaaaaaga
      901 gcaaaagatt cagcaaatgt tattacatta aatgtaggag accaacattt agatttctca
      961 aaagtgataa catcagaaga aggtactttt gaaggttatg aaaagagtta tagtgacata
     1021 gattcaaaag aattacatac gataacagtt aaaaacgcag atttacaaga catatcagca
     1081 gaagaattat ttgatggaat tagattaact acattaggaa gagaaatagt taataaagtt
     1141 aaaaatggat atgctttaac atttgaaaat gaagcaatcc ttactcaaga acaagaagat
     1201 agtgatgata aagataaacc agaaaaatca agctttgata tagttttaag caaggcaaat
     1261 gaaaagtcag aaacaataag tgtttcaagt aaaaaccata agttagttag agacttacac
     1321 aaagtattaa ctgatgtaaa agatggaaaa gaattaaaag tagaggtttt atctggtgat
     1381 tcaagattta caacagcagt agaagttagt aaagagagat tcaaagatgg agaagcagaa
     1441 gctataattt tagttggaga agatgctata gttgatggat tagcatcagc accacttgcc
     1501 tctcaaaaaa atgcaccaat attattatct aaaaaagatt cactaccatc agaaatagaa
     1561 gctgaaatat taagagtact tggaagtaat ctatcttcta agaaaatata tatagtaggt
     1621 ggagaatcta aagtatcaaa agaaactgaa gaaaaacttt ctaaattagg tgtaagtaaa
     1681 gttgagagag tttctggaga agatagattt gaaacttctt tagaaatagc aaaacaatta
     1741 aaagatacat ttaagactgc ttttgtagta ggtggaaatg gagaagctga tgctatgagt
     1801 atatcagcta gagctgctca atttggtgct ccaataatag ttacaggtaa cgaattagat
     1861 gcaaatgctg aaaaattatt aaaaggaaaa gaattagaaa tagtgggtgg agaaaattct
     1921 gtatcaaaag aagttgaaga caaattagtt gatatagatt taaataataa agttgaaaga
     1981 ttagctggag aaaatagaaa agatactaat gctaaagtaa tcaataaata ctatgcaggt
     2041 gcaactaaag catatgtagc aaaagatggt tatgtaggtg gaaatggaca attagttgat
     2101 gcacttacag cagcaccact tgcagctagt tcaaaggctc caatagtatt aactacagaa
     2161 gaactttcta aatcacaaga agaagtagtt gagttaagac ttaagaatgc tactaagtta
     2221 gtacaaatag gtgaaggaat agctaaaaac gctattgaaa aaatagcaga aaaaataaac
     2281 ttatttacta agaactaata agatatagga attaatatta aaagtttatt tagataatat
     2341 atgattatac aatgcgttaa tatgtaagac atagtgtaga tattataaaa tatacaaata
     2401 acaagataaa ataataaaaa taaggtgtct catttagaat tagattgaga taccttattt
     2461 tattttttga ttataatgtg gagaaattca tattgcaaaa attattataa aaa
//
LOCUS       DAMJYN010000205         2504 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.211, whole genome shotgun sequence.
ACCESSION   DAMJYN010000205 DAMJYN010000000
VERSION     DAMJYN010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2504)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2504)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2504
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.211"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            38..772
                     /locus_tag="PC466_003719"
     CDS             38..772
                     /locus_tag="PC466_003719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDF2771064.1"
                     /translation="MKQNKYDDDRFFNKYSKMERSTNGLAGAGEWHVLKKMLPDFKGK
                     RVLDLGCGFGWHCQYAVENGAISAVGVDISEKMLKEARNKTQLDNINYICMPIEDINF
                     PKDSFDVVISSLAFHYIQSFEDICKNISNCLSNKGNFVFSVEHPIFTAYGSQEWYCDK
                     DGNNLHWPVDRYFEEGVRKSNFLGEEVIKYHKTLTTYLNTLMKTGFEILEIIEPQPEE
                     KLLDTIPDMKDELRRPMMLLVSAKKR"
     gene            complement(914..1405)
                     /locus_tag="PC466_003720"
     CDS             complement(914..1405)
                     /locus_tag="PC466_003720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HDF2771065.1"
                     /translation="MNNQQQEVYKKLDELSIPYEAVNHPPVYTIEEMEELKTLHMEFV
                     VKNLFLRDAKGKEHFLVVLGKDKKADLKDIRQQIDSKPLSFASEERLQKYLKLTKGAV
                     TPFGILNDKEAVVKVVFDKDLLKMDKIGIHPNDNTATVFLKFEDMKKLIEENGNEIYY
                     VEV"
     gene            1754..2137
                     /locus_tag="PC466_003721"
     CDS             1754..2137
                     /locus_tag="PC466_003721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2771066.1"
                     /translation="MSTDKVVGIIDEETAELAGIEYTGKIYASSGVIKHIKKKHRCQL
                     SKDIFNDIIDTIKVVLKSPEYIGSHPKKPGKSVEFIKKIDNYILVATELDTKKGYLYV
                     SSMYAIKEAKLESRVNNGRVKQYDG"
BASE COUNT          983 a          280 c          360 g          881 t
ORIGIN      
        1 gttgctaagt gaatatattt aaaatggagg aaactttatg aaacaaaata aatatgatga
       61 tgatagattt tttaataaat acagtaaaat ggaacgttct acaaatggat tagcaggtgc
      121 tggagaatgg catgttttaa aaaaaatgtt acctgatttc aaaggaaaaa gagttttaga
      181 tttaggatgt ggatttggat ggcattgtca atatgcagtt gagaatggag caatttctgc
      241 tgttggagtt gatatttcag aaaaaatgtt aaaagaagct agaaacaaaa cgcaacttga
      301 taatataaat tacatatgta tgcctattga agatattaat tttccaaaag atagttttga
      361 tgtagttatt agttccttgg catttcatta tattcaatca tttgaagata tatgtaagaa
      421 tataagtaat tgtctttcaa ataaaggtaa ttttgtattt tctgttgaac atcctatatt
      481 tactgcatat ggaagtcaag agtggtactg tgataaagat ggcaataatc tacactggcc
      541 agtagataga tattttgaag aaggagtacg taagtcaaat tttctaggag aagaggttat
      601 aaaatatcat aaaacattaa caacttattt aaatacgtta atgaaaacag gatttgaaat
      661 attagaaatt attgaacctc aaccagaaga aaaactgtta gatacaattc ctgatatgaa
      721 agatgagcta cgtagaccta tgatgttact tgtatctgca aaaaaaagat aagtaaatat
      781 aaataatcat tattgtagaa aaaaattgta gaaaataatt acactaatgg agatgattat
      841 accagtggta ttaattacac cagtagtaag gaggcaaaag cattcgttgc ttttgccatt
      901 ttttaagttg caattatact tctacgtagt atatttcgtt tccattttct tctataagct
      961 ttttcatatc ttcaaatttt aaaaatacag tagcagtatt atcatttgga tgtataccta
     1021 ttttatccat ttttaataaa tccttatcaa atacaacttt tacaacagcc tctttatcat
     1081 ttaatatacc aaaaggagtc acagctcctt tagtaagttt caagtatttt tgaagtcttt
     1141 cttctgatgc aaaactaaga ggtttactat caatttgttg acgaatatct tttaaatctg
     1201 cttttttgtc tttacctaat acaactaaaa aatgttcttt tcctttagca tcacgaagaa
     1261 ataggttttt tacaacaaat tccatatgta atgtttttaa ttcttccatt tcttcaattg
     1321 tataaactgg tggatgattt acagcctcat aaggtatgct taactcatct aattttttat
     1381 atacttcctg ttgttgattg ttcatgattt cctcccatta gaaatttatt ttatatataa
     1441 ataatattat cacagaaaac tttaaaagaa aacgttttat ataatataga caatagatta
     1501 tatttttata aagaagcaag aatactcaat aaaacttaaa gaaattaaac aatttctaaa
     1561 aataccttga aaatagaacc ttatttgcca tttataaatt atataaaaag ggattatata
     1621 aagtcatata tgaaaaaact atattatact atcttttctt tttggaataa actatacttt
     1681 aaatatagat atttaattta aataaatttt acagtattaa tagtaaatta tcttagaaag
     1741 gaatgtgctt tatatgtcta cagacaaagt tgttggaatc atagatgaag aaacggcaga
     1801 acttgcagga attgaatata ctggtaaaat ttatgcttct tctggtgtta taaaacatat
     1861 aaagaaaaaa catagatgtc aactgagtaa ggatattttt aatgatataa tagacactat
     1921 aaaagtggta ttaaagtcac ctgaatatat aggaagtcat cctaaaaaac ctggaaaaag
     1981 tgtggagttt ataaaaaaaa ttgataatta tattttagta gctacagaat tagatacaaa
     2041 aaaaggatat ttatatgtat cttcaatgta tgctataaaa gaagcaaaat tagaaagtag
     2101 agtaaacaat ggaagagtaa aacaatatga tggttaacat aatattatta attttcccca
     2161 aaatattgaa aaatattatt atataagtta taatattaat atacacgtag atatttatta
     2221 gttagatttg aggttggaaa aggcacccaa tacgctacta tagagtagtt aatagagatg
     2281 caggatacgc cgccctgcca aatctaatta aattaaaaag agaggattaa ttcctctctt
     2341 tttgtttttt tgagatacta atttaatcta tatagaaaga ttgaaggtca tttatactaa
     2401 aagttttcag ttatatacat taaactaatt aaataagata tttataatct atatatgata
     2461 catattatat attaataaaa gaaaaatata tagaaaatcc ttat
//
LOCUS       DAMJYN010000206         2463 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.212, whole genome shotgun sequence.
ACCESSION   DAMJYN010000206 DAMJYN010000000
VERSION     DAMJYN010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2463)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2463)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2463
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.212"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            26..325
                     /locus_tag="PC466_003722"
     CDS             26..325
                     /locus_tag="PC466_003722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2771067.1"
                     /translation="MKWIKWYSITCICIFIVVAFYMFIFPNKIETIDTSSAYSFVEKK
                     VPNSAVYQGYKKNPVDGTTTIYYSYDNSTHIVRLSHPEDYSRKINWDKVSNIRFD"
     gene            649..2304
                     /gene="ilvD"
                     /locus_tag="PC466_003723"
     CDS             649..2304
                     /gene="ilvD"
                     /locus_tag="PC466_003723"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020457899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HDF2771068.1"
                     /translation="MRSDIKKGIEGAPKRALMYGMGLTKEEIERPLIGIVNAQNEVIP
                     GHLHLDEIAEAAKNGVRMSGGLPLEFPAIGVCDGIAMGHVGMNYSLASRELIADSIEA
                     MAMAHGFDALVLIPNCDKIVPGMLMAAARLNIPSIVVSGGPMLPGKKNGKVYDFNSAM
                     EGVGACKDGTVSEEELEELAMNSCPGCGSCSGLFTANSMNCLTEALGMGIPYNGTAAS
                     HSGERKRIAKYAGMYVMELLKNDIKPRDILTIDAFKNAIAVDMAMAGSTNTVLHLPAI
                     AYESGIEFNLDFFDEISEKTPCLTKLSPSGKHHIEDLHMAGGIPAIMNELSKINGINL
                     DCKTVTGKTIGENIRNCEIENEEVIHTLKNPYSNQGGLAILKGNLALNGAVVKKSAVA
                     EEMLVHEGPARVFNSEEEAVNAIFGKKINKGDVIVIRYEGPKGGPGMKEMLSPTSAVA
                     GMGLDKHVALLTDGRFSGATRGASIGHISPEAMEGGLIGLVEEGDIISINIPDKKLEL
                     KVDEVEIENRKLKFKPLEPKIKHGYLSRYAKLVTSANTGAVLK"
BASE COUNT          950 a          272 c          476 g          765 t
ORIGIN      
        1 attttggtaa agtaggagga attttatgaa atggattaaa tggtatagta ttacatgcat
       61 atgtattttt atagtagtag ctttttatat gtttatattt cctaataaaa tagaaactat
      121 tgatacttca tctgcatata gctttgttga aaagaaagta ccaaatagtg ctgtatatca
      181 aggatacaaa aagaatccag ttgatggtac tactacaatt tattacagct atgataattc
      241 aactcatata gttagattat cacatccaga agactattca aggaagatta attgggataa
      301 agtttcaaac atcagatttg attaatcttt aatatttata aaagtctata tatctaaggc
      361 aaatatatta ttaatcttat tcatagttga gcactttcta ttatagaagt gcttcttctg
      421 atttatatca taaaatatta ctcaacaatt tgtaaaatat attagtttat aaaatatatt
      481 gaaaagataa tattatataa tacgattgtg taagatattg ataaaaaatc gtaataaatt
      541 ttcattagta tatgctaata tttttttaca attttcgtaa ttaattaata gaaaaatata
      601 ttataataat attatgaaaa tttaaaaaag taagaaagag gtaatattat gagaagtgat
      661 ataaaaaaag gaatagaagg agctccaaag agagcgttaa tgtatggaat gggtcttact
      721 aaagaagaaa ttgaaagacc attaataggt atagtaaatg cacaaaatga ggtgattcct
      781 ggtcatctgc atcttgatga aatagcagaa gctgcaaaaa atggagtaag aatgagtggt
      841 ggtttgccat tagaatttcc tgctataggg gtatgtgatg gtatagctat ggggcatgtc
      901 ggaatgaatt attccctggc ttcaagagaa ttaatagcag attcaataga agctatggct
      961 atggcacatg gttttgatgc tttggtactt atacctaatt gtgacaagat agtgccaggt
     1021 atgttaatgg ctgctgcaag acttaatata ccaagtattg ttgtgagtgg agggcctatg
     1081 cttccaggta aaaaaaatgg aaaagtatat gattttaact ctgcaatgga gggtgttgga
     1141 gcatgtaaag atggaacagt aagtgaagaa gaattagaag agttagccat gaactcttgt
     1201 cctggatgtg gttcatgctc tggacttttc acagcaaata gcatgaattg tttaacagaa
     1261 gctttaggca tgggtatacc atataatggt actgctgcgt cacattctgg agaaagaaaa
     1321 agaatagcaa aatatgcagg tatgtatgtt atggagttac ttaagaacga cataaaacct
     1381 agagatattt taacaataga tgcttttaaa aatgctatag ctgttgatat ggcaatggct
     1441 ggttctacaa atacagtact tcacttacct gcaatagctt atgaatcagg aatagagttt
     1501 aacttagatt tttttgatga aataagtgaa aaaactcctt gtttaacaaa attaagtcca
     1561 agtggaaaac atcatattga agatttacat atggcaggag gaataccagc tataatgaac
     1621 gaactttcaa agataaatgg aataaattta gattgcaaaa ccgtaacagg caagactata
     1681 ggggaaaata taagaaattg tgaaatagaa aatgaagaag taatacatac attaaagaat
     1741 ccatatagta accaaggtgg gcttgcaata ttgaaaggaa atcttgctct aaatggagct
     1801 gttgtaaaaa agtcagcagt tgcagaagaa atgttagttc atgaaggacc agcaagagtt
     1861 tttaattcag aagaagaagc tgtaaatgct atttttggta aaaaaataaa caaaggtgat
     1921 gttatagtta taagatatga aggtccaaag ggtggtccag gaatgaaaga aatgctatct
     1981 cctacatcag cagttgcagg aatgggactt gataagcatg tagcacttct tactgatggt
     2041 cgtttttcag gagcaactag aggagcatct ataggccata tttctccaga agctatggaa
     2101 ggtggtttaa tcggactagt tgaagaagga gatataattt ctataaacat accagacaaa
     2161 aaattagagt taaaagtaga tgaagttgaa atagaaaata gaaaattaaa atttaaacct
     2221 ttagaaccga aaataaagca tggatactta agtagatatg ctaaattggt aacatcagca
     2281 aatacaggag cagttttaaa atagtgaact atatttacga aaattagaaa aaattaagaa
     2341 aatattaatt ggatatctta ggtgttatag cactaatgag gtatcctttt tattttgtat
     2401 gaaaaatata ctgtttgtat acaaaaatat taaagatatt ttagtaagtt ttgtatataa
     2461 gca
//
LOCUS       DAMJYN010000207         2397 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.213, whole genome shotgun sequence.
ACCESSION   DAMJYN010000207 DAMJYN010000000
VERSION     DAMJYN010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2397)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2397)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2397
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.213"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(174..1466)
                     /gene="brnQ"
                     /locus_tag="PC466_003724"
     CDS             complement(174..1466)
                     /gene="brnQ"
                     /locus_tag="PC466_003724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HDF2771069.1"
                     /translation="MGEKQINFKDVIVIGFALFAMFFGAGNLIFPPYLGVLSGSSWLI
                     AFIGFLFADGGLALLAVIAATKFNGDTSKMFSRAGKGLSIALGCAMVICIGPLLAIPR
                     TAATTYEMGILPTIGSGISPVIFSIVFFALVLVLTIRPSKVVDIVGSILTPALLIALA
                     VLIVKGIVSPLGEIRDSSLIQNVFAEGITQGYQTMDALAASVFASIIIMSVIAKGYTG
                     EKEKMKATISAGVIAVIGMALVYGGLCYLGATVSQQYGQDVQQTALIVAITAALLGTT
                     GKILLAIIVALACLTTAIGLSSAAGQYFSTLTDGKLKYEHIVIVVCVFSAIISNFGVS
                     TIIKFSSPILSMVYPATITLVILALFSNKIKNDNVFKCAAYMALLVSVLTVATSFGVK
                     IPLVNSLPFASLGFNWIVPVVIAGIIGNFIPSKSSKTA"
BASE COUNT          806 a          393 c          250 g          948 t
ORIGIN      
        1 ataaatcttt tttattttat tgtctttata aatcatactc ctccaaaaat aaatttatca
       61 aatgagatta ataatgttct tttctccaca ataatttaat aattctttta aatataaaaa
      121 ggaattgcca tataatttaa aggcaattcc acaattatca attagtttta ttattatgca
      181 gttttactgc ttttagatgg aataaagttt cctattattc ctgctattac aactggaact
      241 atccagttaa atcctaatga agcaaatggt aagctattaa ctagaggaat ttttacacca
      301 aaacttgttg caactgttaa tacacttact aataatgcca tgtatgcagc acatttgaac
      361 acgttgtcat ttttaatttt attactaaat aatgctagta taactagagt tatagttgct
      421 ggatatacca tacttagtat aggagaagag aattttatta ttgtacttac tccaaagttt
      481 gatatgattg cactaaatac acaaactact ataactatat gctcatactt taattttcca
      541 tctgtaagtg ttgagaaata ttgaccagct gctgaagaaa gacctatagc tgttgttaaa
      601 catgctaatg caactataat agccaataaa attttacctg tagttccaag taaagctgct
      661 gttattgcaa ctattaaagc tgtttgttga acatcttgtc catattgttg agacacagtt
      721 gctccaagat aacataatcc accataaact aatgccattc ctattactgc aattacacct
      781 gcacttattg tggctttcat cttttctttc tcacctgtat aacctttagc tattactgac
      841 atgattataa ttgatgcaaa tacactagct gccaatgcat ccattgtttg ataaccttga
      901 gttatacctt ctgcaaatac attttgaatt aaagaactgt ctcttatttc tcctaatgga
      961 gatacgatac ctttaactat taatactgct aaagctataa gtaaagctgg agttaatatt
     1021 gacccaacta tatctacaac ttttgatggt cttattgtta aaaccaatac tagagcaaag
     1081 aatactatag agaatattac tggacttatt ccagaaccta ttgtaggcaa tatacccatt
     1141 tcataagttg ttgctgctgt tctaggtatt gctaaaagtg gccctataca gattaccatt
     1201 gcacatccta atgcaatact taatcctttg cctgctcttg agaacatctt cgatgtgtct
     1261 ccattgaact tagttgctgc tataactgct aataatgcca aaccaccatc tgcaaaaagg
     1321 aatcctatga aagctattag ccaactactt ccagataaaa ctcctagata tggagggaag
     1381 attaagttcc ctgcaccaaa aaacattgca aatagtgcaa atccaattac aattacatct
     1441 ttaaaattga tttgtttctc acccatttaa agcaccccca tttgaatttt actacctttt
     1501 actaaaaaat aagtccaatc tcttcattaa atgaaaacct tttgacgaga ttttatttaa
     1561 ttatacattt ttgacttaaa tttgtcaatt atgtttcata atttataaaa tcttcacaat
     1621 atttaataca actttcttaa ttaaacaaaa tcaacctgta tactttaaac atagttggtt
     1681 ttttgttttt tctctaattt tccttgataa aattaactat tcagaacaat taaaatatta
     1741 agacttttta gattattcgt tttattatta agttgtattg ctttatatac tgtatatatc
     1801 actctccttt ttacattcat ataatctttt taattcaatt taaattttaa atattttgtg
     1861 tttattatat aatctgaaaa aaaagcagtc aatagcattt ttaatttttt taattttcaa
     1921 aattatgatt cttaaaaaat cgttttcctt ttatcataac acctattaac gttaattctt
     1981 gtagtatttt gtatttattt tgctaaattg acagttaact ttattcaatt tttattctac
     2041 tcacgtagat ttacctcttg tcttttagtc ttaaaaccat tttttctgaa aattccttat
     2101 tatgatttat caacttattt ttcttcatag caattacttt ctaacttcca acttacttaa
     2161 actttgcagt tgctagtatt cacgtttaca tacttatatg tcataattaa ctaaaaattc
     2221 ttaatatatc tctcaatgaa aacaatttac tcatttattt aatacattta tataatcata
     2281 tgtcttaaat tttgttttat tattttatta ttgtcacaat tttatttata ttatattttt
     2341 gtaaaaatca tttaatatgt atacttaaat ttataaaatt actctaaaat tcttttt
//
LOCUS       DAMJYN010000208         2383 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.214, whole genome shotgun sequence.
ACCESSION   DAMJYN010000208 DAMJYN010000000
VERSION     DAMJYN010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2383)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2383)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2383
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.214"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            <1..344
                     /locus_tag="PC466_003725"
     CDS             <1..344
                     /locus_tag="PC466_003725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDF2771070.1"
                     /translation="IKENDIICIEDLQVKNMIRNRKLSRLISDVSWSEFVRQLEYKAN
                     WHGRQIVKVGKFFASSQICNKCGYKNEEVKDLNIREWICPSCNEIHDRDINASINILK
                     EGLRLITIQNK"
     gene            628..1074
                     /locus_tag="PC466_003726"
     CDS             628..1074
                     /locus_tag="PC466_003726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HDF2771071.1"
                     /translation="MKLIWLIVAVLFGIAEMLTPSLTLIWFSVGAVILIFLSSFIESI
                     FLQILIFAVISIAMLVVATKKIVKKDKGYKSNTNLQAMMSKKGIVTEEISPNNTGLVV
                     VEHETWTAISIDGEKIEKGSTVEVLKIEGVKLVVKKVDATVNVTNQ"
     gene            1095..2138
                     /locus_tag="PC466_003727"
     CDS             1095..2138
                     /locus_tag="PC466_003727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH/Band 7/PHB domain protein"
                     /protein_id="HDF2771072.1"
                     /translation="MGTKIVLSIVLIVVVVAISLTCIRVIKQSKVGIIMRLGKFQKVA
                     ETGVHFLIPFLDKMAYVIDLREIVIDFPPQPVITKDNVTMQIDTVVYYKVTDPVRYVF
                     EIANPIAAIENLTATTLRNIIGELDLDETLTSRDIINVKMRTILDEATDKWGIKVNRV
                     ELKNIMPPQDIQVAMEKQMRAERERREAILQAEGNKSAAILQAEGEKQSAILTAEAKK
                     EAMVRVAEGEKESAILVAEGEAEAIRQTAIAKAQGEAEMIKRTQMATAEGLKLVFSAM
                     KEADIDNNILALKSMEALEKMAEGKSTKLVLPSEAVNFLGTFKGIKEVMSDDNKEVLD
                     IKEVLNDNESLKK"
BASE COUNT          975 a          247 c          449 g          712 t
ORIGIN      
        1 taataaaaga gaacgatatt atttgcatag aagatttaca agtaaagaat atgattagaa
       61 atcgtaaact atctcgctta atttctgatg tgtcatggtc agaatttgtt cgtcaattag
      121 aatacaaggc taattggcat ggtagacaaa ttgtaaaggt aggtaaattc tttgcaagtt
      181 cacaaatatg caataaatgt gggtataaaa acgaggaagt gaaggactta aatataagag
      241 aatggatttg tcctagttgt aatgaaattc acgatagaga tataaatgca agtataaata
      301 tattaaaaga aggattaaga ctaataacga ttcaaaataa ataacttatg taagaaccgt
      361 aggaactacg gggatagcct gtggagaatt agtaagacat atgttagtat gcaaaattct
      421 atgaagcagg aaccctgtga ctttagtcat gggaggttca gactactttg taacaatttt
      481 aacaaagtat gttgatataa tactattaaa ttaatcttag attagtttat tctattgatt
      541 tgtagtttaa atttatattc aaaaacattg tataaacata taatttatat agggttttat
      601 aattcatatg aaaagagggt agatagtatg aagttaatat ggttgatagt agcagtctta
      661 tttggaatag cagaaatgtt aacaccaagc ttaacattga tatggtttag tgtaggagct
      721 gtaatactta tatttttaag tagctttata gagagtattt tcttacaaat tttaatattt
      781 gcagtaattt ctatagcaat gttagtcgta gctactaaaa aaatagtaaa aaaagataaa
      841 ggctataaat ctaacactaa tttacaagca atgatgtcta aaaaaggtat tgttacagaa
      901 gagatttctc caaataacac aggtctagtt gtagttgaac atgaaacatg gacggctatt
      961 tctatagatg gtgaaaagat agaaaaaggt tctacagtag aagtattaaa aattgaaggg
     1021 gtaaaattag ttgttaaaaa agtagacgcc acagttaatg tgacaaacca atagaataaa
     1081 ggaggattta tagtatgggt actaaaattg ttttaagtat tgtattaata gtagtagtcg
     1141 tagcaataag tttaacgtgt ataagagtta taaaacaatc taaagtaggt ataataatga
     1201 gacttggtaa gtttcaaaaa gtggctgaaa caggtgtaca tttcttaata ccatttttag
     1261 ataaaatggc atatgtaatt gaccttagag aaattgtaat agattttcca cctcaaccag
     1321 ttataactaa agataatgta actatgcaga ttgatacagt tgtatattat aaagttacag
     1381 atccagttag atatgtgttt gagatagcta atccaatagc tgctattgaa aatttaacag
     1441 ctacaacact aagaaatata attggtgaac ttgatttaga tgaaacatta acatcaagag
     1501 atataataaa tgtaaaaatg agaactatcc ttgatgaagc aacagataaa tggggtataa
     1561 aagtaaatag agtagagtta aaaaatataa tgcctcctca ggatattcaa gttgcgatgg
     1621 aaaaacaaat gagagcagaa agagaaagaa gagaggcaat acttcaagca gaaggtaata
     1681 agtcagctgc aatacttcaa gcagaaggtg aaaaacaatc tgcgatatta acagcagaag
     1741 ccaaaaaaga agctatggta cgtgtagcag aaggtgaaaa agaatctgct atattagtgg
     1801 cagaaggtga agctgaagct ataagacaga ccgctattgc taaggcacaa ggtgaggctg
     1861 aaatgataaa aagaactcaa atggcaacag cagaaggttt aaaattagtt ttttcagcaa
     1921 tgaaagaggc tgatatagac aataatattc tagcattaaa atctatggaa gctcttgaaa
     1981 aaatggctga aggtaagtca acaaaactgg ttttaccttc agaagcagtt aatttcctag
     2041 gaacattcaa aggaataaag gaagttatga gtgatgataa caaagaagta cttgatataa
     2101 aagaagtttt aaatgataat gaatcattaa aaaaataaaa gagttttgtt atcataggaa
     2161 ggatatggaa attaaaggtc gaattaatta aatatagcac aaaaatgcac gttgaaaaga
     2221 agaggactta taaattttta agtcttcttc tttgttttta ttagaaagat gaaattataa
     2281 aaatgaatta acagaatctt tatacaattt atcctttact aatgtaaaaa gtgttatata
     2341 atattatata aaacatatag caaataagca tggttttagt tag
//
LOCUS       DAMJYN010000209         2340 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.215, whole genome shotgun sequence.
ACCESSION   DAMJYN010000209 DAMJYN010000000
VERSION     DAMJYN010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2340)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2340)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2340
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.215"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            <1..391
                     /locus_tag="PC466_003728"
     CDS             <1..391
                     /locus_tag="PC466_003728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017175392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HDF2771073.1"
                     /translation="FYQLPKVFFTNPRYTKISNDAKIAYAILRDRLDLSIKNNWIDEN
                     GDIFFIFTNETLKEILNISSPNKLSKIKKELQSAELFSQIRVGLNKPNKLYIKKPVVT
                     KDDVYLIKKDENPLETNDDKDVSKSYV"
     gene            463..879
                     /locus_tag="PC466_003729"
     CDS             463..879
                     /locus_tag="PC466_003729"
                     /inference="COORDINATES: protein motif:HMM:NF036540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2771074.1"
                     /translation="MNDSFIKKEDNIHSYHTNHQKNEFDNEALKYHLLQELPNHLKAY
                     LSNFDIKDIEIIKSVLLKAKKSFNKNNDTIYRLEDIEFEMINVLKRFKSMLIQKEENV
                     KSMQGYLMQSIKAELEETHTLTMRRQNNLQYNLFNR"
     gene            1303..2022
                     /locus_tag="PC466_003730"
     CDS             1303..2022
                     /locus_tag="PC466_003730"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2771075.1"
                     /translation="MKGLKKCLAGVSTLGLALSLAACNNKDEQIRGKGYTLSDIVNSK
                     EKHQIIVTNKDSSEDDDHENDHVVWAGFIGKGQIEGIYLDGMIYDYGYKDMKNQSDKE
                     LRENLTDMGEDYDVGGRDNNSTFATAQAGTKLYTDLDDMSANPDNDDLADVVSLDAKF
                     KDHGQFNHGSGLTESVSKPAYSNVQKESNKEWITYTSNADSGDTANYQMHIKMGETNL
                     KPQIENVKDTLKKYKNAKEEE"
     gene            2038..>2340
                     /locus_tag="PC466_003731"
     CDS             2038..>2340
                     /locus_tag="PC466_003731"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2771076.1"
                     /translation="MNIIHKLIEEDIKRHPHLKEIYKEQDEALEIAIKAVKLQDDLGW
                     SQTKLANELGTTESIIASIEQGNYPKDHSIINKIHHFYQNGHRYDEKEIDFGDSQGK"
BASE COUNT          994 a          275 c          385 g          686 t
ORIGIN      
        1 gttttatcaa ttaccaaagg tctttttcac aaaccctaga tataccaaaa tttctaatga
       61 tgcaaaaatt gcatatgcta tattacgtga tcggttagat ttatccatta aaaataattg
      121 gattgatgaa aatggagata tattttttat ttttacaaac gaaaccttaa aagagattct
      181 taacattagt agtcccaaca aactttctaa aataaaaaaa gaattacaaa gcgcagagtt
      241 atttagccaa ataagagtcg gtcttaataa accaaataaa ttatatataa aaaaacctgt
      301 agtaacaaaa gatgatgtct atttaatcaa gaaagatgaa aaccctttag aaactaatga
      361 tgataaggat gtatcaaaat catacgtcta aaaatatcaa aatcatacac taatgatact
      421 aatttaaatg atacttacta taatcacact gatgataatg atatgaatga tagttttatt
      481 aaaaaagaag ataatataca ttcatatcat acaaatcatc aaaaaaatga atttgataat
      541 gaagcactca aatatcactt acttcaagaa ctacctaacc atttaaaagc gtatttaagt
      601 aattttgata ttaaagatat tgaaattatt aaaagtgtat tattgaaagc caaaaaatca
      661 ttcaacaaaa acaatgatac aatttatcgt cttgaagata ttgaatttga aatgattaat
      721 gttttaaaac gttttaaatc catgcttatt caaaaagaag aaaatgttaa aagtatgcaa
      781 ggatacctca tgcaatcaat taaagcagag ctagaagaaa cgcatacact cacaatgcga
      841 cgtcaaaata acctacaata taatctcttt aatcgttagt tttaacctaa taaacgatat
      901 tcaaaaacgt cttttaattg aaaggcgttt tttgtgactc taatacagaa agaagctaat
      961 cctttatttt atggtggttg tgaaacaacc acttagatac aaataaaatt aaggaggtgg
     1021 taaacttcaa aattgaaaac tttaacaaaa ggaggcgata aagatgagta atatgaaaaa
     1081 aatcagagtt acattagcat tcattaatgt aatattagct gcaattgaag tatattacca
     1141 atggcaagtt atcaaatcac aaaagaatga ctaattagta aagagaaaca gggctgaaac
     1201 aactaagttt cagtcttgtt ttattacata aattaaaaga ctatttttga taaacttaat
     1261 atatagattg gtatttaagt tattattgga aggatgatga atgtgaaagg attaaagaag
     1321 tgtctagcag gtgtatcaac tttaggttta gcattgagtt tagcagcgtg taataataaa
     1381 gatgaacaaa tcaggggtaa aggttatact ctgagtgata ttgtaaatag taaagaaaaa
     1441 catcaaatca ttgtaacaaa taaggatagt agtgaagatg atgaccatga aaatgatcat
     1501 gtggtttggg ctggatttat cggcaaaggg caaatagaag gtatttattt agatggtatg
     1561 atttatgatt atggttataa agatatgaaa aatcagagtg ataaagaatt aagagaaaac
     1621 ctaactgata tgggtgaaga ctatgatgta ggtggtcgtg ataataactc aacgtttgct
     1681 acagctcaag ccggaacgaa gttatataca gatttagatg atatgagtgc gaaccctgat
     1741 aatgatgatt tagctgatgt ggttagttta gatgctaagt ttaaagatca tggacaattt
     1801 aaccatggaa gtggattaac agaaagtgtt agtaaacctg catatagtaa tgtacaaaaa
     1861 gaatctaata aagaatggat tacttatacg tctaatgcag actctggaga tacagcgaat
     1921 tatcaaatgc acattaaaat gggtgaaaca aatctaaaac ctcaaattga aaatgtaaag
     1981 gatacgttga agaagtataa aaatgctaaa gaagaggagt aataagtagg tgattaaatg
     2041 aatataattc ataaattaat tgaagaagat ataaaacgac atcctcactt aaaagaaata
     2101 tataaagaac aagatgaagc attagaaata gcaataaaag cagtaaaatt acaagacgat
     2161 ttaggctggt ctcaaacaaa attagcaaac gagttaggaa caacagagtc aataattgct
     2221 agtatagaac aaggcaatta tccaaaagat cattcaatca ttaataaaat tcatcatttt
     2281 tatcaaaatg gtcatcgata tgatgaaaaa gaaattgatt ttggtgactc acaaggtaaa
//
LOCUS       DAMJYN010000210         2277 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.217, whole genome shotgun sequence.
ACCESSION   DAMJYN010000210 DAMJYN010000000
VERSION     DAMJYN010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2277)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2277)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2277
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.217"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(379..1293)
                     /locus_tag="PC466_003732"
     CDS             complement(379..1293)
                     /locus_tag="PC466_003732"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2771077.1"
                     /translation="MDLTQYINLDHHIYISEGYLDTLLGQGEIYLKRSQYSNEMESIE
                     RDFGYIAKYRIAFNKREQKSDASIHVHIAKIDVKKKKDGVMTKTLAYFIHSLLEAYPD
                     DKIEVSLHQSASEVAYKDKPIYQKLLTQVFISGELPYIYEVFTVDNREQNLTYYKNLM
                     AQSDYQIRVVNKDDYKHLPIDRMAQKQEAVHYLKQMIGLDLSINNRNLSILEVQKLKR
                     KYATVKKTKKRSRYIIQKVEASNNNERLLILDNQYISQLYRYDNIVEGLSDKDINEIF
                     LVLKNDIQYMTDVTEFINSQNEIKEFIY"
     gene            complement(1707..1892)
                     /locus_tag="PC466_003733"
     CDS             complement(1707..1892)
                     /locus_tag="PC466_003733"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2771078.1"
                     /translation="MNQIAIKEDGVYSIDDDRLQENEREFFEEVMKGIKYDIEQVKAI
                     EKQKDSENYLKYCLLFK"
BASE COUNT          705 a          411 c          273 g          888 t
ORIGIN      
        1 ttaaaccctt gatacatttg cgttcaaacg ctctctaaaa aggttttaaa aaggtttata
       61 aaaagatatt aaaaatagac gcttctacat tattaaatta ggcaaaatga ctcttttaac
      121 tacacacaat tagattgcac ttaagctata agtacataac gtacactttt aaattaaaat
      181 tatcctatat tgattaagat gtggcaaaac tactccatta tttagacaaa actcttcctt
      241 tacttataaa accgcttcat acgttgttac aatttgaccc gcatactcac agacaaaact
      301 cttcctttac ttatatacat cttttttcaa catacaaaaa gctatgctgt gaatttacaa
      361 catagcttct ctaatgattt aatatatgaa ttcctttatc tcattttgac tattgataaa
      421 ctcagtaaca tccgtcatgt attgaatgtc attctttaac actaaaaata tttcgttgat
      481 atctttgtct gacagtcctt ctactatatt gtcatatcta tataattgac taatatattg
      541 attgtccaat attaataacc gctcattatt gtttgatgct tccacctttt ggataatgta
      601 gcgactccgc ttttttgtct ttttcactgt tgcatattta cgctttagtt tctgaacttc
      661 tagaatagat aagttacgat tattgatgct taaatctaat ccaatcatct gtttaaggta
      721 atgcaccgct tcttgttttt gagccattct atctataggt aaatgtttgt agtcgtcttt
      781 atttactact ctaatttgat aatccgattg tgccattaaa tttttataat acgttaagtt
      841 ctgctctcta ttgtctactg taaatacttc atagatatac ggaagctcgc cacttataaa
      901 aacttgagtt agtaattttt gatatatagg cttatcttta taagcgactt cactcgctga
      961 ttgatgtaat gacacttcaa tcttatcatc aggataggct tctaatagtg agtgaatgaa
     1021 ataagccaat gttttcgtca taacgccatc tttctttttc ttaacatcga ttttagctat
     1081 atgtacatgt atcgatgcat cacttttttg ttctcgcttg ttgaaagcaa ttctatattt
     1141 agctatataa ccaaagtctc gctctatcga ttccatctca ttgctgtatt gagatcgttt
     1201 aagataaatc tcaccttgtc ctaacaacgt atctaaatag ccctctgaga tgtatatatg
     1261 atgatctaag ttaatgtatt gtgttaagtc catatttgct ctcctccttt tcgtaaacaa
     1321 caaatatata caaatatcta attcactttc attatacatg agtatgctca tgtatacaag
     1381 cggtgtcttc ttccctttat cttaattacg tactcaacgt acacattatg atattaaaaa
     1441 agaagcggtg gttaaccgct tcttcgtact tcatttatct atatgtctcc caaagatatc
     1501 tctatctact atactatttg tagtcgcttt gtaatccttt tgttgtagta atacgctata
     1561 acatagactc ctactaagaa gctaattaga aacgtgataa gcaatggcat aactgcaata
     1621 tatactatca tcaatgactc ttttaataca ttatacatgc tgctagttat tagcagatta
     1681 cttggcttac tttcagtcct ttagatctat ttaaacaata agcaatactt cagataattt
     1741 tcactatctt tttgcttctc aatagctttt acttgttcta tatcatattt aatacccttc
     1801 ataacttctt caaaaaattc tctttcattt tcttgtagcc tatcatcatc tatgctataa
     1861 acaccgtctt ctttaattgc tatttggttc aaatcaagct catatttatt ttctaaataa
     1921 ttatcaatat ggcttttagc cgtttcaata cttctaaaat atatttctaa atgtttgtta
     1981 actgcatttg tttcaatagg tttgaaaata gatgtagcat cattttatac ttcttgtaaa
     2041 tagacggcta ttattttgta cacaacgtac acgtatactg tataaaaaag gtaactacaa
     2101 ctttaaaatg gcgtcatagt tacacatgta caaactactt cgtatttttc atagactagt
     2161 ataagtggtt tgaattgcac attcaaccaa tataagcctt taaccgcttc tatttttaac
     2221 ttatattgat ttctattaat aacagttagt ttaggatacc tacatattat ttatgat
//
LOCUS       DAMJYN010000211         2242 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.218, whole genome shotgun sequence.
ACCESSION   DAMJYN010000211 DAMJYN010000000
VERSION     DAMJYN010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2242)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2242)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2242
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.218"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            91..1542
                     /locus_tag="PC466_003734"
     CDS             91..1542
                     /locus_tag="PC466_003734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine:cation symporter family protein"
                     /protein_id="HDF2771079.1"
                     /translation="MNFLNGILTSINNAVVFVNNYLWSYILIIMLVVIGIYFTIKTNF
                     VQFRYFIEMFRLLGDGTANKNAKKEGKISSFQAFCISTSSRVGTGNIAGIAIAVVAGG
                     PGAVFWMWLIALIGSASSFVESTLAQIYKVKDGQAFRGGPAYYMEQGLNKKWMGILFS
                     ILITICYGFVFNAVQANTVSLAFNNAFGISKMAMGIGLGILTAIVIFGGVHRVAKVSE
                     IIVPVFAGLYILVALAIVVMNITEIPSVIALIVESAFDFKGMAIGTFMGVVMTGVKRG
                     LFSNEAGMGSAPNAAATAHVTHPVKQGLIQSLGVFTDTIIICSCTAFMVLLYSGYSSS
                     GATGIELAQEALTHHIGPVGNIFIAVCIFLFAFSSIVGNYYYGESNMEFMSGSKTKLN
                     VFRVFVVGMVLFGSLTQVDVVWNLADLFMALMAIINLIAIALLGKYAFIALKDYTSQK
                     KSGIKDPVFIADEIEGLEKVSEWHRELSEEHLG"
     gene            complement(1762..2223)
                     /locus_tag="PC466_003735"
     CDS             complement(1762..2223)
                     /locus_tag="PC466_003735"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HDF2771080.1"
                     /translation="MIYEGKLIGKDLKIGIINSRFNEFITSKLLSGAEDCLLRHDVSP
                     ENIEIVWVPGAFEIPLVAQKMAKSGRYDAIICLGCVIRGATSHYDYVCSEVSKGIAKV
                     SLDSELPVIFGIVTTENIEQAIERAGTKAGNKGYDCAMNALEMANLFKSLN"
BASE COUNT          755 a          265 c          394 g          828 t
ORIGIN      
        1 aattaatgaa tttttaacaa ggaattattc atttttttga ttttaagatt tattgagaaa
       61 acaaaactaa ataggggggt aattaatata atgaattttt taaatggtat tttaacgagt
      121 attaacaatg cagtagtatt tgtaaacaat tacttatggt cgtatatctt aattataatg
      181 ttagttgtaa ttggtattta ctttactatt aaaacaaatt ttgtacaatt cagatatttt
      241 atagaaatgt ttagacttct gggtgatggt acagcgaata aaaatgcaaa aaaggaagga
      301 aaaatctctt catttcaagc attttgtata agtacatctt caagagttgg aactggaaat
      361 atagctggaa tagcaattgc agtggtagca gggggacctg gtgctgtatt ttggatgtgg
      421 cttatagcat taattggttc tgcatcaagc tttgttgaga gtacattagc tcagatttac
      481 aaagtgaaag atggtcaagc ttttagaggt ggaccagcgt attatatgga acaaggtcta
      541 aataaaaaat ggatgggtat tttattctca atacttataa ctatatgtta tggttttgta
      601 tttaatgcag ttcaagcaaa tactgtttca cttgcattta ataatgcatt tggaataagt
      661 aaaatggcta tgggaatagg tcttggaatt ttaactgcaa tagttatttt tggtggagtg
      721 catagagttg caaaagtttc tgaaataata gttcctgtat ttgcaggatt atatatatta
      781 gttgctttgg ctatagttgt aatgaatata acagagatac caagtgttat agcattgata
      841 gttgaaagtg catttgattt taaaggaatg gcgattggta catttatggg agttgtaatg
      901 actggagtga agagaggtct attttctaat gaagcaggta tgggtagtgc tcctaatgct
      961 gctgcaacag cacatgtaac tcatcctgta aaacaaggtt taattcaatc tttaggtgtt
     1021 tttacagata ctataataat atgtagttgt acagcattca tggtattatt atattcaggt
     1081 tatagtagta gtggagcaac tggaattgaa ttagctcaag aagctttaac tcatcatata
     1141 ggaccagttg gaaatatatt tatagcagtt tgtatattct tgtttgcatt tagttctata
     1201 gttggtaatt actattatgg tgaatcaaat atggagttta tgagtggaag taagactaaa
     1261 cttaatgtat ttagagtttt tgttgtaggc atggttttat ttggttcact tactcaagta
     1321 gatgtagttt ggaatcttgc agacttattt atggcattga tggcgataat aaacttaata
     1381 gcaatagcac ttttaggaaa atatgcattt attgctttaa aagattatac aagtcaaaaa
     1441 aaatcaggaa taaaagaccc tgtgtttatt gcagatgaaa tagaaggcct agaaaaggta
     1501 tcagagtggc atagggaatt atctgaggaa catttaggat aaaaaatagt ataaaattat
     1561 aaaaccattt tgaaagacta gagtatgtat atgctttata tgaatataat attgaattaa
     1621 tttatattac tggaattttt aattccagta atattttttt attatataat ttagctttat
     1681 taaaagtttt tattattaaa aatagcttat ttatcgtaaa gtgaatgata ttggtttttt
     1741 aattattatg aatgttggta tttaatttaa agacttaaat aaatttgcca tttctagcgc
     1801 attcatagca caatcataac ctttatttcc agcttttgta cctgctcttt caatagcttg
     1861 ttcaatattt tctgtagtta cgattccaaa tataacaggt aattcactgt ctaaagatac
     1921 ttttgctatc cctttagaga cttcactaca tacataatca taatgagaag tagcccctct
     1981 tataacacag cctaaacaga ttatagcatc atacctacca cttttagcca ttttttgagc
     2041 aacaagagga atctcaaaag ctccaggtac ccaaactatt tctatatttt ctggagaaac
     2101 gtcatgtctt aaaagacagt cttcagctcc tgataaaagt tttgatgtta taaattcatt
     2161 aaaacgagaa tttattatac ctatttttaa atcttttcca ataagttttc cttcatatat
     2221 catttttatt tcctccaatt tt
//
LOCUS       DAMJYN010000212         2159 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.219, whole genome shotgun sequence.
ACCESSION   DAMJYN010000212 DAMJYN010000000
VERSION     DAMJYN010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2159)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2159)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2159
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.219"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            83..>2159
                     /locus_tag="PC466_003736"
     rRNA            83..>2159
                     /locus_tag="PC466_003736"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          645 a          428 c          610 g          476 t
ORIGIN      
        1 atctaatttg taatatataa agctgataac tttttaaaat tatcgaagtt gatagcttct
       61 aatctatcaa acctttttaa ctggtcaagt tattaagggt gcagggcgga tgccttggca
      121 ctaggagccg atgaaggacg tgataagctg cgataagctt cggggagttg cacgtaaact
      181 ttgatccgaa gatttccgaa tgaggaaact cacttagagt aatgtctaag tatcattaag
      241 tgaatacata gcttaatgag gggaactcag ggaactgaaa catctaagta cctgaaggaa
      301 gagaaagaaa ttcgattccg taagtagcgg cgagcgaacg cggattagcc caaaccaata
      361 aagttttctt tattggggtt gcggacatat cataacgaag aggtatcgta attgaagagg
      421 tttggaaaga cccaccacag aaggtaatag tcctgtatgt taaacgagaa gacttcagat
      481 atgatccaga gtaccacggg acacgtgaaa ccctgtggga agcaggaggg accaccctcc
      541 aaggctaaat actacctagt gaccgatagc gtatagtacc gtgagggaaa ggtgaaaaga
      601 accccgggag gggagtgaaa tagaacctga aaccctgcac ttacaagctg tggaagcaca
      661 tttcttgtgt gaccgcgtac tttttgtaga acgggccaac gagttacgtt aagtagcaag
      721 gttaagcact taaggtgcgg agccgtagcg aaagcgagtt ttaactgagc gttcagttac
      781 ttgacgtaga cccgaaaccg ggcgacctac ccatgagcag gatgaagcga aagtaaaatt
      841 tcgtggaggt ccgaacccac gagcgttgaa aagctcgggg atgacttgtg ggtagcggtg
      901 aaattccaat cgagcccgga gatagctggt tctccccgaa atagctttag ggctagcctc
      961 aaggtgagag atacggaggt agagcactga atgtcctagg gggtattgca cctaccgaag
     1021 actatcaaac tccgaatgcc gtcatcttat acttgggagt cagactgtgg gtgataagat
     1081 tcatagtcga aagggcaaca gcccagatcg tcagctaagg tccctaaatg taagttaagt
     1141 ggtaaaggat gtgggattgc acagacaacc aggatgttgg cttagaagca gccactcatt
     1201 caaagagtgc gtaatagctc actggtcgag tgatcctgcg ccgaagattt ccggggctaa
     1261 aacttactac cgaagctacg gcatcagtaa tgatgggtag gggagcttcc catacgggtt
     1321 gaagcatgac cgtaaggaca tgtggacagt atgggagtga gaatgttggc atgagtagcg
     1381 agatgtgggt gagaatccca caggccgtaa acccaaggtt tccaggggaa ggttcgtccg
     1441 ccctgggtta gtcgggacct aagctgaggc cgaaaggcgt aggtgatgga caacaggttg
     1501 atattcctgt actaccgata accgtttgag agaagggatg acacagtagg ataagctaag
     1561 cacactgttg gttatgtgtg cccaagcatt gaggcagtca aagtaggcaa atccgctttg
     1621 ataatgctgg gatgtgatgg ggagcgaaat ttagtagcga agtagctgat ttcacactgt
     1681 caagaaaagt ctctatcgag gttaaaggta cccgtaccgc aaaccgacac aggtgggtga
     1741 ggagagtatc ctaaggccag cgagagaact gttgttaagg aactcggcaa aatgaccccg
     1801 taacttaggg ataaggggtg ccaccatcag gtggccgcag agaataggcc caagcgactg
     1861 tttaccaaaa acataggttt ctgctaagtc gcaagacgat gtataggagc tgacgcctgc
     1921 ccggtgctgg aaggttaagg ggatctgtta gagcaatcga agcagtgaac ttaagcccca
     1981 gtaaacggcg gccgtaacta taacggtcct aaggtagcga aattccttgt cgggtaagtt
     2041 ccgacccgca cgaaaggcgt aacgatttgg gcactgtctc aacaacagac tcggtgaaat
     2101 tgtaattccg gtgaagatgc cggatacctg cgacaggacg gaaagacccc atggagctt
//
LOCUS       DAMJYN010000213         2077 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.220, whole genome shotgun sequence.
ACCESSION   DAMJYN010000213 DAMJYN010000000
VERSION     DAMJYN010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2077)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2077)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2077
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.220"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            258..872
                     /locus_tag="PC466_003737"
     CDS             258..872
                     /locus_tag="PC466_003737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HDF2771081.1"
                     /translation="MEEVIAKIITIENGFKEIENIAKKIVKNNDSKKCYYLSIYLYRS
                     EYYQVRELAVFILGFISVTISEALLFLKDNVSKDENWRVQEILAKSFDYYCSEVGYEK
                     ALPVIKEWLNSDSPNIKRAVTEGLRIWTSRDYFKSNPDVAISLLSSLKEDDSEYLRKS
                     VGNALRDISKKYPDLVKKELDSWDISNKKVEFVYKLASKCILAK"
     gene            890..1252
                     /locus_tag="PC466_003738"
     CDS             890..1252
                     /locus_tag="PC466_003738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2771082.1"
                     /translation="MKLRDEYTCPLELTHDMIKGKWKSIILWRLRIGPTSLSKLEKEI
                     NGINQKMLLEQLKELIEFGLVDKKTYKGYPLKVEYSLTPIRGKQILDALAIMQDIGIS
                     FMLDNGMEDILKEKGVLK"
     gene            1358..1855
                     /locus_tag="PC466_003739"
     CDS             1358..1855
                     /locus_tag="PC466_003739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbhB/YbcL family Raf kinase inhibitor-like
                     protein"
                     /protein_id="HDF2771083.1"
                     /translation="MKVTSTGIVNGVIEDKYGKRGTQFNEGGMPTYSLPLKFEDAPKN
                     TVSFAVFLEDKDSVPVCGFAWIHWLAVNITKDELNENESVTATDFVQGTTSWHGKLGG
                     LDRLEASVYGGMAPPDRPHVYEIHVFALDTILDLEKGFYMNEFFKAIEGHVLDTFTLK
                     GSYSN"
BASE COUNT          791 a          231 c          335 g          720 t
ORIGIN      
        1 ttctattagt atactcaaat catgtaaaat ttatataact caattaattt tttaaataca
       61 actttataat ataaaactta taataaaagt aaatttatat gttaaatgag gttgattttt
      121 tattattttt tatttatgct agtactaaag acttgcaaac gttttttgac aagtctttat
      181 tttgtctaaa ttaaacaaac ttttttacaa ataaatacat aaaatttaaa ctaatctatt
      241 tattggagga gataaaattg gaagaagtaa ttgcaaaaat tattactata gaaaatggat
      301 tcaaagaaat tgaaaacatt gctaaaaaaa ttgtaaaaaa taatgactca aaaaagtgtt
      361 attatctatc aatctactta tataggtcag aatattatca agtaagagaa ttggctgtgt
      421 ttatacttgg ttttatatca gtaactattt ctgaagcttt gttattttta aaagacaatg
      481 tgagtaaaga tgaaaactgg agagtacaag aaatactagc taaatcattt gattattatt
      541 gcagtgaagt aggatatgaa aaggcacttc ctgttataaa agaatggctt aattctgata
      601 gtccaaacat aaaaagggct gtgacagaag gtcttagaat ttggactagt agagactatt
      661 ttaaatctaa tcctgacgtt gctatatcac tactttctag tttaaaagaa gatgatagcg
      721 aatacttgag aaagtctgta ggtaatgctc ttagagatat aagtaaaaaa tatccagatt
      781 tagtaaaaaa agaattagat tcatgggata tatcaaataa aaaagttgag tttgtatata
      841 agcttgcttc aaaatgtatc ttggcaaagt aaaatggagg tgaacttatt tgaaacttcg
      901 tgatgagtat acttgcccat tagaactaac acatgatatg ataaaaggca aatggaaatc
      961 tattatatta tggagattac gcataggacc aacctcctta tcaaaacttg aaaaggaaat
     1021 caatggtatt aatcaaaaga tgttacttga acaacttaaa gaattaattg aatttggtct
     1081 tgtagataaa aagacatata aaggttaccc acttaaagtt gaatactcac ttacacctat
     1141 tcgagggaaa caaatattgg atgctttggc tataatgcaa gatataggaa ttagctttat
     1201 gttggataat ggtatggaag atattcttaa ggaaaaaggt gttttaaaat aaatagatac
     1261 ccacaaaaaa gtaagtaatt taccattatt ttcaactggt atataattaa attatagata
     1321 tattctatta atttattata ataggaggta aattattatg aaagtaacta gtacaggtat
     1381 agtaaatggt gttatagaag ataaatacgg taaaagagga actcagttca atgaaggtgg
     1441 tatgcctaca tattcactac ctctaaagtt tgaagatgct ccaaagaata cagtatcctt
     1501 tgctgtattt ttagaagata aagactctgt tcctgtatgt gggtttgcat ggatacattg
     1561 gttagctgta aatataacaa aagatgagtt aaatgaaaat gaaagtgtaa cagctactga
     1621 ttttgtacaa gggactacta gttggcatgg caaactagga ggtcttgaca gattagaggc
     1681 cagtgtatat ggtggaatgg ctcctccaga cagacctcat gtctatgaaa tacatgtatt
     1741 tgcacttgat actatccttg accttgaaaa aggattctat atgaatgaat ttttcaaagc
     1801 tattgaaggg catgttttag atacatttac actaaaagga agctattcta attaattagg
     1861 tttactatag ctaatcatta attaaatgct acatttaatt gatgattagc ttaattgtta
     1921 ttagaatatt ttctgcactt tatcttaata tatattttag ttgactggta ttttaatttc
     1981 tattagatta ttatcaattt atataaattg attttagctt aaaacttact tatctatttc
     2041 agtttctatt agaattatta ttagactcat taaaata
//
LOCUS       DAMJYN010000214         2076 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.221, whole genome shotgun sequence.
ACCESSION   DAMJYN010000214 DAMJYN010000000
VERSION     DAMJYN010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2076)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2076)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2076
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.221"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(53..403)
                     /locus_tag="PC466_003740"
     CDS             complement(53..403)
                     /locus_tag="PC466_003740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2771084.1"
                     /translation="MAIVDKIFNEIKLMVARLLLGKKYSEYEEKDLVYNTEEEVILIT
                     LKRLVFQGNVNEAEEILFDKAKTVTSENMQYIAIEFYTMLMEKTDEELEAMNFSKQEV
                     YQGIEDIRKVLNLE"
     gene            complement(626..817)
                     /locus_tag="PC466_003741"
     CDS             complement(626..817)
                     /locus_tag="PC466_003741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2771085.1"
                     /translation="MLDRFFGEGGFGGCAWWIIILFFLFLAFQDCWAEMDLCAWIPFL
                     ILLLILCECGDVFDGGCGC"
     gene            complement(936..1484)
                     /locus_tag="PC466_003742"
     CDS             complement(936..1484)
                     /locus_tag="PC466_003742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF2771086.1"
                     /translation="MGGVDSVLSSVKVKNIIQANYKKDSKQYDEYIDSLKKADIEPVL
                     LKDNMNIVINSAEINIHPASKSKYESSNDYSIITNISYGAHKFLFAGDAEEERLSEFI
                     NGNTLKYDFVKMPHHGRYDKLTETFLESTSPQYAVITCSEKKEPEEGVLKILERLNIK
                     TFLTSSGEVVINSDGKTLSVNQ"
     gene            complement(1627..>2076)
                     /locus_tag="PC466_003743"
     CDS             complement(1627..>2076)
                     /locus_tag="PC466_003743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDF2771087.1"
                     /translation="TIGSLNRNKARLKVAGLQEHIANQRNDFLQKLSTKLIKENDIIC
                     IEDLQVKNMIKNRKLSRLISDVSWSEFVRQLEYKANWHGRQIVKVGKFFASSQICNKC
                     GYKNEEVKNLNIREWICPSCNETHDRDINASINILKEGLRLITIQNK"
BASE COUNT          654 a          375 c          208 g          839 t
ORIGIN      
        1 gtataatatt ctcaccttaa cattaattta tttcaatatt ttcatatatc ttttattcta
       61 aattcaatac ttttctaata tcttctatac cttgataaac ttcttgttta gaaaaattca
      121 tagcttctaa ttcttcatca gtcttttcca taagcatagt ataaaattct attgctatat
      181 actgcatatt ttcactagtt acagtcttag ctttatcaaa taaaatttct tctgcttcgt
      241 ttacatttcc ctgaaaaact aatcttttta aagttataag tataacttct tcttctgtat
      301 tatacactaa atctttttct tcatattcac tgtatttttt tcccaataaa agtcttgcaa
      361 ccataagttt tatctcattg aaaatcttat ccactatagc catttttaca tctcctataa
      421 ataaatttta ttttcttttt aattatatca gactttattg taaaaattat tatatgtaaa
      481 tgaaataatt caaaaataaa ttctaacaat aaaaaaaaga aggtagcggg ggatttccga
      541 ctaccttcaa acactagatt gtgattggtt tggtatttta tttataccca ccataagctt
      601 tattaaatca tctaaattga tttttttagc atccacatcc tccatcaaaa acgtcaccac
      661 attcacaaag tattaataat aatattaaga aaggtatcca tgcacataag tccatttcag
      721 cccaacaatc ttggaatgct aagaataaga agaataatat tattatccac caagcacatc
      781 caccaaatcc gccttcacca aaaaatctat ccaacataat atgttacctc ctagtcattt
      841 tgtatgtgga gtttcagctc ctaaaatata ctatgtttaa ggggtaatat ttgctaatga
      901 tttttttaaa ttttttttag atattttaaa aaaaattatt gattcacact caatgtctta
      961 ccatcactat tgataactac ctctccacta gaagtcaaaa atgtttttat attcaatctt
     1021 tccaatattt ttaaaacacc ttcctctggt tcttttttct ctgaacatgt aataacagca
     1081 tattggggtg aagtagactc taaaaatgtt tcagttaatt tgtcatatct tccatgatga
     1141 ggcattttaa caaaatcata ttttaaagta tttccattta taaactctga caatctttct
     1201 tcctctgcat ctcctgcaaa taaaaactta tgtgctccat agcttatatt agtgattatt
     1261 gaataatcat ttgaactctc gtacttgctt tttgaagccg gatgtatgtt tatttctgca
     1321 ctattgatta caatattcat attatctttt agtagcactg gttctatatc agctttttta
     1381 agtgagtcaa tatattcatc atattgctta ctatctttct tataatttgc ttgtataata
     1441 ttctttactt taacactaga taacacacta tctactccac ctatatggtc cttatctaaa
     1501 tgggttaaac tgaacctcct atgactaaag tcacagggtt cctgcttcat agaattttgc
     1561 atactaacat atgtcttact aattctccac aggctatccc cgtagttcct acggttctta
     1621 catacgttat ttattttgaa ttgttattag tcttaatcct tcttttaata tatttatact
     1681 tgcatttata tctctatcgt gagtttcatt acaactagga caaatccatt ctcttatatt
     1741 taagttctta acttcctcat ttttataccc acatttattg catatttgtg aacttgcaaa
     1801 gaatttgcct acttttacaa tttgtctacc atgccaatta gccttgtatt ctaattgacg
     1861 aacaaattct gaccatgaca catcagaaat taagcgagat agtttacgat ttttaatcat
     1921 attctttact tgtaaatctt ctatgcaaat aatatcattc tcttttatta atttagtaga
     1981 tagtttttgt agaaaatcat ttctttgatt ggctatatgt tcttgaagtc ctgcaacttt
     2041 taatcttgct ttattcctat ttaaactacc gattgt
//
LOCUS       DAMJYN010000215         1995 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.222, whole genome shotgun sequence.
ACCESSION   DAMJYN010000215 DAMJYN010000000
VERSION     DAMJYN010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1995)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1995)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1995
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.222"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(57..1274)
                     /locus_tag="PC466_003744"
     CDS             complement(57..1274)
                     /locus_tag="PC466_003744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallo-hydrolase"
                     /protein_id="HDF2771088.1"
                     /translation="MLGKKCMDYLQTLGKISSTTNGLTRLILTQEHKKSIDLISSWME
                     GLNLDIEIDDIGNVIGTYKSSFPNAPTLVVASHQDSVKCGGIFDGMLGIIVPLVGLEE
                     AKHNNRSYPFNIKLIAFAEEEGTRFETSLMGSKVFAGTFKEELLKSVDENGITLEEAV
                     TKFGFNTKNLTNLHPRKDVDAYLEFHIEQGPVLENESLPAGIVSSITGFKSFKISVNG
                     KSGHAGTLPMNMRLDAGCCACECVLAIEKVAKTTADLVATVGKMNFYPSSSNVVPERA
                     EFTLDVRSCSQEILDNSVEKIFNEISHICENRKLNYTSELAFENVPVPCSNKITKIIE
                     KSFIDLNLNPFYIYSGAGHDAQEMDNITDIGMVFIRCAGGVSHNPNESVSVDDLDTAV
                     KIFLKILDNLDLK"
     gene            complement(1465..1878)
                     /locus_tag="PC466_003745"
     CDS             complement(1465..1878)
                     /locus_tag="PC466_003745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2771089.1"
                     /translation="MELEITEKIEKQDEDTIFQGLLKYNLARLEDKNPVDLGIYIRDK
                     AGKIVAGFIGVTHGNWLSIKYLWVSEKLRYKGTGSQLLYKTEKIAKERGCKYVFLDTF
                     SFQAPKFYEKFGYHKVFSLENYPLTGKRYYYRKIL"
BASE COUNT          687 a          325 c          225 g          758 t
ORIGIN      
        1 taaatataaa gtgatttttt agattatata ttttaatata ctttcttata taaaaattat
       61 tttaaatcaa gattatctag tatttttaaa aatattttta cagcagtatc caagtcatct
      121 acagaaacac tttcattagg attatgactt acgcccccag cacatcttat aaataccata
      181 ccaatatcag ttatattatc catttcctga gcatcatggc cagcaccact ataaatataa
      241 aaaggattaa gatttaaatc tataaaactt ttttctatga tttttgttat tttattagaa
      301 catggtacag gaacattttc aaaagcaagt tcacttgtat aattaagttt tctattttca
      361 catatatgtg atatttcatt aaatatcttt tctacagaat tatcaagaat ttcttgtgaa
      421 caagagcgta catcgagtgt aaattcagct ctttcaggta ccacatttga tgaagatgga
      481 tagaaattca tctttcctac agtagcaacc aaatcagcag tcgttttagc tactttttcg
      541 atagctaata cacattcaca ggcacaacat ccagcatcaa gtctcatatt cattggaagt
      601 gtaccagcat gtccagactt accatttact gatatcttaa aacttttaaa tcctgtaata
      661 cttgatacaa ttccagcagg aagagattca ttttctaaaa caggaccctg ctcgatatga
      721 aattctaaat atgcatctac atcttttcta ggatgcaaat ttgttaagtt ttttgtatta
      781 aatccaaact ttgttacagc ttcttcaagt gtaattccat tttcatcaac agatttaaga
      841 agttcctctt taaaagtacc agcaaaaact ttacttccca ttaaagaagt ttcaaatcta
      901 gttccttcct cttcagcgaa agcaattagc ttaatattga aaggataaga cctattattg
      961 tgttttgctt cttcaagacc aactagaggc actattatac ctaacatacc atcaaatata
     1021 cctccacact ttacactatc ttgatgagat gcaactacta atgtgggagc atttggaaag
     1081 cttgatttat atgtacctat aacgtttcca atgtcatcaa tttcaatatc aagatttaaa
     1141 ccttccatcc atgaactaat taaatcaata gattttttat gttcttgagt caagataagt
     1201 cttgtaagac catttgttgt tgaacttatt tttcctaatg tttgtagata atccatacat
     1261 ttttttccta acatatttac ctcctaaaaa tataattttt atttaagcta agattagctt
     1321 ttatacttat aatttttgaa ctttcaaata attttgtatg tatagtaaaa tactatttta
     1381 gtattaataa tgatataaaa acataaagtc tgtagacgaa gagcagaagt tttaagttaa
     1441 aaatataaaa tatgattttt attattatag tatttttcta taataatatc tctttccagt
     1501 tagaggataa ttttcaagtg aaaatacttt atggtatcca aatttctcat aaaatttagg
     1561 tgcttgaaaa ctgaatgtat ctaaaaaaac atatttacaa cctcgttctt tagcaatttt
     1621 ttcagtctta tataaaagtt gacttccagt acctttatat ctaagcttct cactaaccca
     1681 taagtatttt atagaaagcc aattaccatg agtaacacct ataaaacctg caacaatttt
     1741 acctgcttta tctcgaatat atattcctaa atccactggg tttttatctt caagtctagc
     1801 aagattatat tttaataatc cttgaaaaat agtatcttca tcttgttttt ctattttttc
     1861 tgtaatttct aattccatat ttgaactttc tccttgtata atcttttgta tattggtatt
     1921 ttttaataaa atcagtagaa agaatatagt ttaacattat tctaataggc atttatgcta
     1981 atgtcaaact aataa
//
LOCUS       DAMJYN010000216         1983 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.223, whole genome shotgun sequence.
ACCESSION   DAMJYN010000216 DAMJYN010000000
VERSION     DAMJYN010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1983)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1983)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1983
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.223"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            178..294
                     /gene="rrf"
                     /locus_tag="PC466_003746"
     rRNA            178..294
                     /gene="rrf"
                     /locus_tag="PC466_003746"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            301..375
                     /locus_tag="PC466_003747"
     tRNA            301..375
                     /locus_tag="PC466_003747"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:333..335,aa:Asn,seq:gtt)
     gene            380..454
                     /locus_tag="PC466_003748"
     tRNA            380..454
                     /locus_tag="PC466_003748"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:413..415,aa:Glu,seq:ttc)
     gene            460..535
                     /locus_tag="PC466_003749"
     tRNA            460..535
                     /locus_tag="PC466_003749"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:493..495,aa:Val,seq:tac)
     gene            541..617
                     /locus_tag="PC466_003750"
     tRNA            541..617
                     /locus_tag="PC466_003750"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:575..577,aa:Asp,seq:gtc)
     gene            628..702
                     /locus_tag="PC466_003751"
     tRNA            628..702
                     /locus_tag="PC466_003751"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:660..662,aa:Thr,seq:tgt)
     gene            717..801
                     /locus_tag="PC466_003752"
     tRNA            717..801
                     /locus_tag="PC466_003752"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:751..753,aa:Tyr,seq:gta)
     gene            811..884
                     /locus_tag="PC466_003753"
     tRNA            811..884
                     /locus_tag="PC466_003753"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:843..845,aa:Gly,seq:tcc)
     gene            895..971
                     /locus_tag="PC466_003754"
     tRNA            895..971
                     /locus_tag="PC466_003754"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:929..931,aa:Arg,seq:tct)
     gene            981..1056
                     /locus_tag="PC466_003755"
     tRNA            981..1056
                     /locus_tag="PC466_003755"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1014..1016,aa:Gln,seq:ttg)
     gene            1068..1143
                     /locus_tag="PC466_003756"
     tRNA            1068..1143
                     /locus_tag="PC466_003756"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1101..1103,aa:Lys,seq:ttt)
     gene            1146..1234
                     /locus_tag="PC466_003757"
     tRNA            1146..1234
                     /locus_tag="PC466_003757"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1180..1182,aa:Ser,seq:tga)
     gene            1252..1342
                     /locus_tag="PC466_003758"
     tRNA            1252..1342
                     /locus_tag="PC466_003758"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1286..1288,aa:Ser,seq:gct)
     gene            1351..1427
                     /locus_tag="PC466_003759"
     tRNA            1351..1427
                     /locus_tag="PC466_003759"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1385..1387,aa:Pro,seq:tgg)
     gene            1513..1588
                     /locus_tag="PC466_003760"
     tRNA            1513..1588
                     /locus_tag="PC466_003760"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1546..1548,aa:Trp,seq:cca)
     gene            1649..1725
                     /locus_tag="PC466_003761"
     tRNA            1649..1725
                     /locus_tag="PC466_003761"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1683..1685,aa:Pro,seq:tgg)
     gene            1732..1808
                     /locus_tag="PC466_003762"
     tRNA            1732..1808
                     /locus_tag="PC466_003762"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1766..1768,aa:Ile,seq:gat)
     gene            1812..1887
                     /locus_tag="PC466_003763"
     tRNA            1812..1887
                     /locus_tag="PC466_003763"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1845..1847,aa:Phe,seq:gaa)
     gene            1895..1971
                     /locus_tag="PC466_003764"
     tRNA            1895..1971
                     /locus_tag="PC466_003764"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1929..1931,aa:Met,seq:cat)
BASE COUNT          501 a          449 c          535 g          498 t
ORIGIN      
        1 aatgtattta gcttatcgat actaataggt cgaggacttg accaatatta tttgatgtta
       61 ttcattaaga tatatgtgca gtttttagag tgttaactct aaaaaaaaat aaaaaaagta
      121 ttgacaaaaa tagtaaaaaa tgttaatatt atacttgtcc tagcaacaag aaaaaaatgt
      181 ggttataata gcagagaaga tacacctgtt tccattccga acacagaagt taagttctct
      241 agcgctgatg gtacttggtg ggaaactgcc tgggagagta gggcatagcc acgtgaatgt
      301 tccaaggtag ctcaacggtg gagcaaccgg ctgttaaccg gtaggctgtg ggttcgagcc
      361 ccacccttgg agccattatg gctcgttggt caagaggtta agacaccgcc ctttcacggc
      421 ggtaacaggg gttcaattcc cctacgagtc accatttgtg ggatcatagc tcagctggga
      481 gagcacctgc cttacaagca gggggtcaca ggttcgagcc ctgttggtcc caccatttgc
      541 ggcctggtag ttcagttggt tagaatgcca gcctgtcacg ctggaggtcg agggttcgag
      601 ccccttccag gtcgccaaaa taaaaatgct ggtgtggctc aacggtagag cagctgactt
      661 gtaatcagca ggttgtaggt tcgattccta tcaccagctc catgtaaaac taatacggag
      721 gatttcccga gcggccaaag ggggcagact gtaaatctgt tgtcatcgac ttcggtggtt
      781 cgaatccacc atcctccacc aattaaatat gcgggtgtag ctcaatggta gagttctggc
      841 cttccaagcc agctgtgagg gttcgatccc cttcacccgc tccaaagaaa gcgtgggtgc
      901 atagctcagc tggatagagc aacgcccttc taaggcgtgt gtccggggtt cgaatccctg
      961 tgcgctcacc acatatatat tggggattag ccaagtcggt aaggcacatg actttgactc
     1021 atgtatgcgt aggttcgagt cctgcatccc cagccaaata aaaatatggt ctattagctc
     1081 agtcggtaga gcacctgact tttaatcagg gtgtcccgcg ttcgagtcgc ggatagatca
     1141 ccaatggaga ggtgtccgag tggtttaagg agctggtctt gaaaaccagt gacttcgaaa
     1201 ggggccgtgg gttcgaatcc caccctctcc gccaaaaaaa tgactgaatt tggagaagta
     1261 ctcaagtggc tcaagaggat cccctgctaa gggattaggc tgggtaaccg gtgcgagggt
     1321 tcgaatccct ccttctccgc cattcaaaaa cgaggtgtag cgcagtttgg tagcgcacat
     1381 ggtttgggac catggggccg ggggttcgag tcccttcacc tcgaccaact taagctttta
     1441 gttcagttgg ttagagtgcc caactcatgg ctagtaattc tagggtttga gtccatgaag
     1501 gttattcttc ataggggtgt agctcagttg gtagagcgtc ggtctccaaa accgtgcgcc
     1561 gggggttcga gtccctccac ccctgccaaa taaaaaggac ttgaaaaaag ttggatttta
     1621 gagtagtata agatagtaaa taagatttcg aggtgtagcg cagtttggta gcgcacatgg
     1681 tttgggacca tggggccggg ggttcgagtc ccttcacctc gaccaagaaa agggcctata
     1741 gctcaggtgg ttagagcgca cgcctgataa gcgtgaggtc gctggttcga gtccagctag
     1801 gcccaccatt tgcccagata gctcagtcgg tagagcaggg gactgaaaat ccccgtgtcg
     1861 gtggttcgat tccgcctctg ggcaccagga atacggcggt atagcttagt tggctagagc
     1921 gttcggttca tacccgaaag gtcataggtt cgactcctat taccgctacc atctaactat
     1981 atc
//
LOCUS       DAMJYN010000217         1964 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.224, whole genome shotgun sequence.
ACCESSION   DAMJYN010000217 DAMJYN010000000
VERSION     DAMJYN010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1964)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1964)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1964
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.224"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            164..1642
                     /gene="putP"
                     /locus_tag="PC466_003765"
     CDS             164..1642
                     /gene="putP"
                     /locus_tag="PC466_003765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006715280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium/proline symporter PutP"
                     /protein_id="HDF2771090.1"
                     /translation="MLAVYFLILLVIGYYGYKQATGDLREYMLGGRNIGPYVTALSAG
                     ASDMSGWMIMGLPGEVYTTGLSAAWLAIGLTIGAYVNYILVAPRLRVYTEKANDSITL
                     PNYFTHRLNDNSNIIKIISGGIIVVFFTLYTHSGMVSGGKLFNSAFGLDYHTGLIVVS
                     VIVIAYTFFGGYLAVSLTDFFQGVVMLIAMVMVPIVAMMQLGGIDAFSQAANLKPTNL
                     DLFKGTTIVGIISFFAWGLGYFGQPHIIVRFMSIKSVSQLKTARRFGISWMAISLIGA
                     VCVGLIGIAFVQDRGVKLNDPETLFILMGQILFHPLVGGFLLAAILAAIMSTISSQLL
                     VTSSSLTEDFYKLIRGEEAAKKHKKEFLLVGRLSVLIIAIISIIIAWTPNDTILNLVG
                     NAWAGFGAAFGPLVLLSLYWKGLSRTGAIFGMISGSVVVIIWIVFVKPLGEYIDFFNL
                     YEIIPGFLTSLIVTYIVSLITKKPNRDVEKELEEVKKLVKEK"
BASE COUNT          616 a          263 c          361 g          724 t
ORIGIN      
        1 agattcatta aataccaaaa atttaaattt atcctttaaa taactcttgt tttttgtata
       61 attattgtat gtaacaaaaa taaatataag ggagttattt aatatgtttg ttttagctac
      121 atctttatca agccaagtga atcttgactg gcggacatat atcatgcttg cagtatattt
      181 tctaatttta cttgttattg gatattatgg ttataagcag gcaaccggag atttaagaga
      241 atatatgctt ggtggaagaa atataggacc ttacgttact gcattatctg ctggagcttc
      301 agatatgagt ggttggatga ttatggggtt acctggagag gtttatacaa caggtttatc
      361 agcagcttgg ttagctattg ggttaactat cggagcttat gttaactaca tacttgtagc
      421 accaagactt cgtgtgtaca ctgaaaaagc gaatgactca atcacattac ctaactattt
      481 tacacatcgc cttaatgata attctaatat tattaaaatt atctctggtg gtattattgt
      541 tgtattcttt acactatata ctcactcggg tatggtttca ggtggtaaat tatttaatag
      601 tgcgtttggt ctagattatc atactggtct tattgtagtt tcggtgattg ttattgctta
      661 tacattcttt ggggggtatt tagcagtatc attaactgac ttctttcaag gtgtagttat
      721 gttaattgcg atggttatgg tacctattgt agccatgatg cagctcggag ggattgatgc
      781 tttttctcaa gcagcaaatt taaaaccgac taatttagat ttatttaaag ggacaactat
      841 tgtgggaatt atttctttct ttgcttgggg attaggttac tttggtcaac cgcatattat
      901 agtacgattc atgtcaatca aatctgttag tcaattaaaa actgccagaa gatttggtat
      961 tagttggatg gctattagtt taataggtgc tgtatgtgta gggttgatag gtattgcttt
     1021 tgttcaagat agaggagtta aattaaatga tccagaaaca ctttttattt taatgggcca
     1081 aattttattc catccattgg ttggtggttt ccttcttgca gcaattttag cagctattat
     1141 gagcacaatc tcctcacaac tacttgttac ttctagttca cttacagagg atttctataa
     1201 attaattaga ggcgaagaag ctgcaaaaaa acataaaaaa gagtttttat tagtaggtcg
     1261 attatctgtt cttattatag caattatatc tattataatc gcatggactc caaatgatac
     1321 tatacttaat cttgttggta atgcatgggc tggatttggt gcagcatttg gtccactggt
     1381 attactatct ctctattgga agggattaag tcgtacagga gctatttttg gtatgatatc
     1441 aggatcagtt gtagtcatta tttggattgt ttttgtgaaa ccattaggag aatatattga
     1501 cttctttaat ttatatgaaa ttattcctgg atttttaaca agtttaattg tgacttatat
     1561 cgtaagtctt ataactaaaa aaccgaatag agatgttgaa aaagaattag aagaagttaa
     1621 aaaacttgta aaagaaaaat aacattttat catttaaaga ggtagaacaa gaaatcgtgg
     1681 ttctatctct tattttttta tttacaaatt tcattttatt gaagtatata gtttttatca
     1741 atttcaataa cacttatcta atatggtagc aaattggcat tacctatcta ctactacacg
     1801 atgcttatat tgaaattgct aaagaacatc ccacgatgat tttttaccgg gaaacaaatg
     1861 ggatttgcag attcgaagaa gcagaaggat tgtgcaagca caatcccaaa atctcattat
     1921 tttttataaa taaataatat atataaggaa gcagagagat acac
//
LOCUS       DAMJYN010000218         1922 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.225, whole genome shotgun sequence.
ACCESSION   DAMJYN010000218 DAMJYN010000000
VERSION     DAMJYN010000218.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1922)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1922)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1922
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.225"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            29..427
                     /locus_tag="PC466_003766"
     CDS             29..427
                     /locus_tag="PC466_003766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2771091.1"
                     /translation="MNKKKKLIGIAISFLLIISIINPLQVEAEAIIESSVYISSIKEN
                     YTYDNTKFKTIKSKSRHKSRKYNKSKVKLKKRSIRTKKYGYQTINKYKRRNARRHNIL
                     TKLVLSIIVIFLVIVLVVLIFIKRKKKKFY"
     misc_binding    863..1126
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            1277..1828
                     /locus_tag="PC466_003767"
     CDS             1277..1828
                     /locus_tag="PC466_003767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan transporter"
                     /protein_id="HDF2771092.1"
                     /translation="MKTNTKKLTLNAILLAMGLLIHQITPAIGLPMKPDVPLAMLFVI
                     LVLNRDDYKTCLIAGIVTGIFTALTSSFPGGQIPNVIDKTLTANIVFLLMNISYNMPF
                     IKKLAKKTQDTVVVAIIMPIGTLVSGTIFLLAAQAIVGLPGASFTALFLAVVLPAVLI
                     NLVAGIFLFKIVSLSIRRVSYQA"
BASE COUNT          808 a          184 c          292 g          638 t
ORIGIN      
        1 agttaaaaat ttttatgagg gggaaaatat gaataagaag aaaaaattga ttgggatagc
       61 tatatctttt ctacttataa tcagtattat aaatccatta caagtagaag cagaagctat
      121 tattgagtct agtgtataca tttcttcaat aaaagagaat tatacatatg ataatactaa
      181 atttaaaact attaaatcta aaagtagaca taaaagtagg aaatataata aaagtaaagt
      241 aaagttgaaa aaacgaagta taagaactaa aaagtatgga tatcaaacta taaataaata
      301 taaaagacga aatgcaagaa gacataatat cctaacaaaa ttagtattgt ccataatagt
      361 catatttttg gttatagttt tagtagtgct aatatttatt aaaagaaaga agaaaaaatt
      421 ttactaaaaa taattaaaag aatatcattt ttctaatcat tggtatctat ttaataatat
      481 gatgtaatta aaatggagta atattctgtt tcaaaggagg catataaata caggaatgag
      541 tattaaatga tggttaatta agtaaattta ttgataaatg tacttaatta actttgaaga
      601 atttaattcc tcatgaatca aaatataaaa ttacatcaac agttattcac aaaattaata
      661 taagaagaat tagagccaaa gagcagacta ttagaccatt aaagtaatta ttcatagaat
      721 tttgtatatg aaaagaaatg tatagtataa tttacttttt ttataaaaaa tagattacaa
      781 aatatatttt ttataaaaag gtattgacat tttttagaaa aaagaatatc attattttaa
      841 caacaaaatt caatacaata aattaaatcc tatgacaagg aagagtagtt aaatttaggt
      901 tcagtataga gagctgagga tggtggaatc ttagcaagaa aaaatttgat gaatggccct
      961 tagaggaata aattgaaatc atagttttga gagtagactt tatcgtcagt cgcacgttat
     1021 agcgaataag gtatgtaagt acctgataat gagatgtatg aaaattgaat tttatattaa
     1081 tttttatata atttaggtgg caacgcggat aatctccgtc ctattagttt aggacggagt
     1141 tttttatttt actgaaaatt taaaagatag aaggtggtga gaaagatgtt atgaatttca
     1201 aaagctaaag atgatgatat agtaggttgg caaaaaaata aattgaaaat taaaaaaata
     1261 ggaggaagta caaaaaatga aaacaaatac aaaaaaatta actttaaatg caatactttt
     1321 agcgatggga ttattaatac atcaaatcac accagctata ggattaccaa tgaagccaga
     1381 tgtaccacta gcaatgttat ttgtaatatt ggttttaaat agagatgatt ataaaacttg
     1441 tttgatagcg ggtatagtaa caggaatatt tacagcactt acatcaagtt ttccgggagg
     1501 tcaaattcct aatgtaatag ataaaactct tacagcaaat atagtatttt tattaatgaa
     1561 tattagttat aatatgcctt ttataaaaaa attagctaag aaaacacaag atactgtagt
     1621 agttgcaata ataatgccaa taggaactct tgtaagtgga actatctttt tattagcagc
     1681 tcaagctata gttggtcttc caggagcttc atttacagct ttattcttag cagtagtatt
     1741 accagctgtt ttaataaatc tagttgcagg aatattttta ttcaagattg ttagtctatc
     1801 aataagaaga gttagttatc aagcttaact acgaaataat attttacttt ataaagcatt
     1861 ataataacta aataacataa gaataaagta gattataact attttattct tatgttgttt
     1921 aa
//
LOCUS       DAMJYN010000219         1869 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.226, whole genome shotgun sequence.
ACCESSION   DAMJYN010000219 DAMJYN010000000
VERSION     DAMJYN010000219.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1869)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1869)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1869
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.226"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(<1..1300)
                     /locus_tag="PC466_003768"
     CDS             complement(<1..1300)
                     /locus_tag="PC466_003768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003474560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HDF2771093.1"
                     /translation="MKKYDLLILGFGKGGKTLAKSASAQGMKVAVVEKSQKMYGGTCI
                     NIGCIPSKTLIHEGLESGSFNQSLHRKEEVVTSLNKKNYHNLADDKNITVLDNKAVFK
                     SNTEVNLLDEQGKVIDTLTANNIVINTGATPVIPGIQGIQKSKYLYDSTGIMNLNEKP
                     KRLVIVGGGYISLEFASMFANFGTEVTVLEMKERLMPKEDEEIVSHVIKDLEDKNVKI
                     VLDTQTSAFEDQDDHTVVKTNRGDIEADAVLLAIGRKPNTEDLNLENTDIKLGERGEI
                     KVDNQLKTDVNHIYTIGDVKGGMQFTYISLDDFRIVNDQLLGSGERTTENRGSIPYTV
                     FIDPPLSRIGLTAKEAKEQGYNIKEGKLPVNNIPRHKINNDTRGLFKVVIDTKTNKIL
                     GATLYGLQSEEMINIIKLAIDQDIDYTILRDNIYTHPTMIE"
     gene            complement(1287..1721)
                     /locus_tag="PC466_003769"
     CDS             complement(1287..1721)
                     /locus_tag="PC466_003769"
                     /inference="COORDINATES: protein motif:HMM:NF014173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HDF2771094.1"
                     /translation="MNLEFNIAVHVLVFLSRHSYEKFSSTELSKKVCVNPVQLRRVMS
                     QLSESDYITAKKGKYGGYSMKGNVLNASLAELFRLFATNKSFGRIYTGTKESECEISN
                     QMSHVMSEYHYEEFRILEAFYQNISIEDILNKILMEGYNEKV"
BASE COUNT          561 a          324 c          232 g          752 t
ORIGIN      
        1 attctatcat tgttggatgg gtataaatat tgtctcttaa aattgtataa tcaatatctt
       61 gatcaatagc aagtttaata atatttatca tttcttcaga ttgtagtcca tatagtgtag
      121 ctcctaatat tttatttgtt ttagtatcta tcactacttt aaacaggcct ctagtgtcat
      181 tattgatttt gtgtcttggt atattattaa ctggaagctt accttcttta atattataac
      241 cttgttcttt cgcttcttta gccgttaaac caatacgaga taatggtggg tctataaata
      301 cagtatatgg tattgaccct ctattctctg tagtacgctc acctgaacct aataattggt
      361 cgttaacaat tctaaaatca tctaaagaaa tataagtgaa ttgcatgccc cctttaacat
      421 caccaatcgt atagatatga ttaacgtcag ttttcagttg attatcaact ttaatttcgc
      481 cacgttcacc aagtttaata tcagtatttt ctaaatttaa gtcttctgta tttggttttc
      541 taccaattgc gagtagaact gcatctgctt caatatcgcc tctattcgtt tttacgacag
      601 tatgatcatc ttgatcttca aatgctgaag tttgagtatc tagcacaatt tttacatttt
      661 tatcttctaa gtctttaatt acatgagaaa cgatttcttc atcttctttt ggcattagtc
      721 tttctttcat ttctaataca gtcacttctg tcccaaagtt ggcaaacata gatgcaaatt
      781 ctaaagaaat ataacctcca cccacaataa ccagtcgttt aggcttctca tttaaattca
      841 tgataccagt agaatcgtat aaatattttg atttttgaat gccttggata cctggaataa
      901 caggtgttgc tcctgtattt ataacgatgt tatttgctgt taaagtatct atgactttac
      961 cttgttcgtc taataaattt acttcagtat ttgatttaaa gacagcttta ttatctaata
     1021 ctgttatatt tttatcatct gctaaattat ggtagttctt tttgttaagt gaggtcacaa
     1081 cttcttcttt acgatgtaat gattgattga atgaaccact ttctaatcct tcatgtatta
     1141 atgttttaga tgggatacac cctatgttga tacatgtacc tccatacatt ttttgagatt
     1201 tttcaactac tgctactttc attccttgtg ctgatgcact tttggcaagt gttttaccac
     1261 ctttgccaaa tcctaaaatt aataaatcat actttttcat tgtatccctc cattaaaatt
     1321 ttatttagta tatcttcaat tgatatattt tgatagaatg cttctaaaat tctaaactct
     1381 tcgtaatgat attctgacat aacatgactc atttgatttg aaatttcaca ttcactttct
     1441 ttagttcctg tgtaaattct tccaaacgat ttattagtgg cgaataatct aaataattct
     1501 gctaaggatg cattcaaaac attacctttc atactataac cgccatactt cccttttttc
     1561 gctgtaatat aatcactttc tgataattga ctcataactc ttcttagttg aactggattt
     1621 acacaaactt tctttgatag ttcggtacta ctgaactttt cataagaatg cctacttaaa
     1681 aaaactagta catggactgc gatattaaac tctaaattca atgaagtacc tccaaatttc
     1741 aaaagcaact tttatagtta catttaatca cattaattta tagagtacaa ataaaatgga
     1801 atgtaattta tttcaacttt ttatttatct taaaaattct ttttagattc taacaatttg
     1861 tttatttga
//
LOCUS       DAMJYN010000220         1836 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.227, whole genome shotgun sequence.
ACCESSION   DAMJYN010000220 DAMJYN010000000
VERSION     DAMJYN010000220.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1836)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1836)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1836
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.227"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(62..262)
                     /locus_tag="PC466_003770"
     CDS             complement(62..262)
                     /locus_tag="PC466_003770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HDF2771095.1"
                     /translation="MNNGTVKWFNADKGFGFIERGNGNDVFVHYSGIAGEGYKSLEEG
                     QNVDFDIIEGQRGEQATNVAAI"
     gene            1094..1363
                     /locus_tag="PC466_003771"
     CDS             1094..1363
                     /locus_tag="PC466_003771"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2771096.1"
                     /translation="MTKALNDINKTSERVFKNGNSKAISLGKQTIQLVKFEVGDKVEV
                     QEMNGGLFIKKKEESIEDRITNFFKNGGKYTESEIDFGESVGREI"
     gene            1360..1695
                     /locus_tag="PC466_003772"
     CDS             1360..1695
                     /locus_tag="PC466_003772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002477817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HDF2771097.1"
                     /translation="MNIKQFDILYIDLDPTLGREKQKIRPCLVINNQMSIEGTDFVWI
                     LPITNREKRFETDIEVKTKKGLITGVIDTIQMRSLDLNARKYNYKDELQDRLKNDVLQ
                     AVQTYLKPL"
BASE COUNT          699 a          274 c          282 g          581 t
ORIGIN      
        1 aatagtttgt taatcaaaaa aagcacttaa tcacaacgga ttaaatgctt tgaactttaa
       61 cctatattgc tgcaacattt gttgcttgtt caccacgttg accttcaatg atatcaaaat
      121 caacattttg gccttcttct aaagatttat agccttctcc ggcaatacca gagtaatgaa
      181 cgaaaacgtc attcccatta cctctttcga tgaaaccaaa acctttgtct gcgttaaacc
      241 attttactgt accgttattc atatagaata cctccacgtg cttttgcaca taatatttgt
      301 aacaaattca taactaaaaa agaggatatt caaatcaata cactacaatt taattcacga
      361 tctttgatta cgttagatta actatacact taataatgtc ataagtacag aactattttt
      421 aacctttgtt gattttagtg ataattaata tacggctcac atttgctttt taaaagctaa
      481 taaacaattt tgaatataaa actatataag gatagctttg cttgaaatct attttagcaa
      541 aaaaaccact cactaaaatt agtgagtggt ttttaaagtc ttaatagcaa atttctaata
      601 attggataag agttattatg ctatatgtat tatatcacaa tttttggggt tgaaaagctt
      661 tgtgaataat ctttgacgtc aaaaataaag agctatcaaa aggatagctc taagccttcc
      721 cctataatta taagtataat aaacgaggat aatactatga aacgctaaga gaagacgtat
      781 atttattata gcacagcatt tatgccgaga atatttattg agattcagaa ggcccttaac
      841 taaacttgaa gacgaatgtc ggcatatctt gagctattaa gccgataatt cgacaagttt
      901 agggattgtt aagggttccg aagctcaacg tcaataaagc aattggaata acgcaaaaat
      961 catcattaac ttttataaat attatattgt taaattttat tcaatgattc acaatcacaa
     1021 tatccaagca tttactaatg tatttacata agtaagtaca aatgatacgc tatagataag
     1081 gagatgatac caaatgacaa aagcattaaa tgacatcaat aaaacatctg aacgtgtctt
     1141 taaaaatgga aacagtaaag caataagtct gggcaaacaa acgattcaac tcgttaaatt
     1201 cgaagtggga gataaagtcg aagttcaaga aatgaatggt ggactattca tcaaaaagaa
     1261 agaagaatcg attgaagata gaattacaaa ctttttcaaa aatggtggta aatacactga
     1321 atcagaaatt gattttggtg aaagcgttgg tcgtgaaata tgaatataaa acaatttgat
     1381 atactttata tcgacctaga cccaacactt ggtcgtgaaa aacaaaagat acgaccatgt
     1441 ttagtcataa acaaccaaat gagtattgaa ggtactgatt tcgtttggat attgccaata
     1501 acaaatcgag aaaaacgctt cgaaacagat attgaagtta aaactaagaa aggtttaatt
     1561 actggagtta tagatactat tcaaatgcgt tctcttgact taaatgcgcg taaatacaac
     1621 tacaaagatg aattgcaaga tagattaaaa aatgacgttt tacaagctgt acagacctat
     1681 ctgaagccat tataaattca aaacacccgt tttattttat agtaaaaggg attggttcta
     1741 tttaagtaat ttttgtttaa ctatttaaat taaataagga tttctagcgt attttaaagg
     1801 gagcctgtcc tatattattg tcgtggtcaa aattga
//
LOCUS       DAMJYN010000221         1825 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.228, whole genome shotgun sequence.
ACCESSION   DAMJYN010000221 DAMJYN010000000
VERSION     DAMJYN010000221.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1825)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1825)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1825
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.228"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            94..663
                     /gene="mocA"
                     /locus_tag="PC466_003773"
     CDS             94..663
                     /gene="mocA"
                     /locus_tag="PC466_003773"
                     /EC_number="2.7.7.76"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor cytidylyltransferase"
                     /protein_id="HDF2771098.1"
                     /translation="MINAVIMASGFARRMGANKLLLNYKGCSIIEHVFREVSKIDFHQ
                     VVVVSQYEEVLLLCNKYGFEYIDNKNANIGQSESIKLGVLNSSKCDGYMFFVGDQPFI
                     DNLYIDKIINTFKLDRDFIVIPRYKDMCGNPVIFPYSKKEELLALKEDEKGKTILKNS
                     SKIKYVEVPKEMLFDIDTKMDYERIGGKL"
     gene            660..1679
                     /locus_tag="PC466_003774"
     CDS             660..1679
                     /locus_tag="PC466_003774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-binding protein"
                     /protein_id="HDF2771099.1"
                     /translation="MKLIKTIDAVGQVLCHDITQIIPGEFKGRKFKKGHIVKEEDIPV
                     LLSLGKDNLYVWEKSEGMVHENEGALFLKELTAGENLDFSEIKEGKIDFIAACDGLLK
                     IDVDALFDLNCVGEIMMATLHNNFIVNKGLKVAGTRVIPLVIDEKKLEDAKKVVGNRK
                     IVNVVPFKPKKVGIVTTGNEVFYSRIVDKFGPVIEEKVKGFGCEVIGQTICPDDKEII
                     KSAIKEFISQGAELICCTGGMSVDPDDVTPTAIKETGADLVTYGSPILPGAMFLLAYY
                     GEVPIMGIPGCAMYHKTTVFDIVLSRVLIDEKLDKYDIARYGHGGLCMNCDVCTYPAC
                     NFAKI"
BASE COUNT          731 a          164 c          348 g          582 t
ORIGIN      
        1 tttatatgat attatatata tagataatat caatagagat attataaaaa tcatagaact
       61 atcaatatat tataaatacc aaggatgata tatatgataa atgcagtgat aatggcatca
      121 ggctttgcca gaagaatggg agcaaataaa cttttattaa attataaagg ctgttctata
      181 atagaacatg tatttagaga agttagcaag attgattttc atcaagttgt agtagtaagt
      241 caatatgaag aggttttgtt attgtgtaat aaatatggtt ttgaatatat agataataaa
      301 aatgcaaata taggtcaaag tgaatctata aaattaggag ttttaaatag ctcaaaatgt
      361 gatggttata tgttctttgt aggagaccag ccatttattg ataacttata tatagataaa
      421 attataaata cttttaaatt agatagagat tttatagtaa ttccaagata caaagatatg
      481 tgtggaaatc cagtcatatt cccatatagt aagaaagaag aattgttggc acttaaagaa
      541 gatgaaaaag gtaaaaccat tttaaaaaat tcatcaaaaa taaagtatgt agaagttcct
      601 aaagaaatgt tatttgatat cgatacaaaa atggactatg agagaatcgg gggtaaatta
      661 tgaagctaat aaaaactata gatgctgttg gacaagtttt atgtcacgac ataactcaaa
      721 taatacctgg agaatttaaa ggaagaaaat ttaaaaaggg tcacatagta aaagaagaag
      781 atattccagt gttattatct cttggtaaag ataatttgta tgtatgggaa aagtcagaag
      841 gaatggttca tgaaaatgaa ggcgcattgt ttttaaaaga actaactgct ggagaaaatt
      901 tagattttag tgaaataaaa gaaggaaaaa tagattttat agcagcatgt gatggtctat
      961 taaagataga tgttgatgca ctttttgatt tgaattgtgt tggagaaata atgatggcta
     1021 ctcttcataa taattttata gtaaataaag gtttaaaagt agctggaaca agagtgatac
     1081 ctttggttat agatgagaaa aaattagaag atgcaaaaaa agtagttggt aatagaaaaa
     1141 tagtaaatgt agtacctttt aaacctaaga aagtaggaat tgttactaca ggaaatgaag
     1201 tgttttatag cagaattgtt gataaatttg gaccagtaat agaagaaaaa gtaaaaggct
     1261 ttggttgtga agttatagga cagactatat gcccagatga taaagaaatt ataaagagtg
     1321 caataaaaga atttataagt caaggagcag aacttatctg ttgtactggc gggatgagtg
     1381 tagacccaga tgatgttacg ccaacagcta taaaagaaac tggagctgat ttagtgacat
     1441 atggttcacc aatattacca ggagctatgt ttttacttgc ttattatgga gaagttccaa
     1501 ttatgggtat accaggatgc gcaatgtatc ataaaactac agtatttgat atagttttat
     1561 ctagggtttt aattgatgaa aagcttgata agtatgatat agctagatat ggtcatggtg
     1621 gcctttgtat gaactgtgat gtatgtactt atcctgcatg taattttgct aaaatataaa
     1681 gttattaaaa aagagtattt acaaattaag tactcttttt aaatatgaaa caaaacagct
     1741 agaatgatgt tttaagaaaa gcatatttat ttagaaatta taataactta ttttcaatgt
     1801 gtaaaagaat gaataaagtt gcaat
//
LOCUS       DAMJYN010000222         1805 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.229, whole genome shotgun sequence.
ACCESSION   DAMJYN010000222 DAMJYN010000000
VERSION     DAMJYN010000222.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1805)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1805)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1805
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.229"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            148..1197
                     /locus_tag="PC466_003775"
     CDS             148..1197
                     /locus_tag="PC466_003775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF2771100.1"
                     /translation="MFKKIVAIASSIIVSTICLTGCDFNSNDKKDESSSSKNLDKVTI
                     AEVTHSVFYAPQYAAITKGFFEDEGIKIDLINTQGADKTMAALISGEANVGLMGPEAS
                     IYVYNQNKNDYAVNFAQLTKRDGSFLVARKKMPNFSYNDLKGTEILGGRKGGVPLMTF
                     EYVLKEKGLTIGENLKAGNVNVRTDVQFGVMAGAFAGGEGDFTTAFEPTATAMEKEGS
                     GYIVTSIGKDSGEIPFTAYSTTRSYMKNNKDLIQRFTNAVYKGQLWVQQASSKEVAKA
                     MQPFFEDISLEDLTTVVDRYKSIDAWSQNPVLKEEGLKKLMTVMKEAKELDKEAPYKD
                     IVNTEFANNAIKNIK"
     gene            complement(1347..1694)
                     /locus_tag="PC466_003776"
     CDS             complement(1347..1694)
                     /locus_tag="PC466_003776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HDF2771101.1"
                     /translation="MHENKKNLLDGSLAQYNDTAVPKIPVFAGNDITSEVYYFKPNQV
                     LNAHRHPNGEQIFVFLKGEGKMKLGEHECDVKNGDTVFVPTGEWHEITNGSNEEMVAV
                     QITKINAGAEYRG"
BASE COUNT          669 a          245 c          282 g          609 t
ORIGIN      
        1 acatattact aaaaaaacta aacataaaac tgaaaattat tattaagttt ttgtagaaat
       61 attataagca tagatacatt tttgtaacaa ctacaataaa tttttaatac tatatactat
      121 tcgtatgtct tatgggaggt atttattatg tttaaaaaaa tagtcgcaat agcaagctct
      181 atcattgtaa gtacaatatg tctaactgga tgtgatttta actctaatga caaaaaagat
      241 gaatcttctt cgtctaaaaa tctggataaa gtaactatag cagaagttac tcactctgtt
      301 ttttatgctc cacagtatgc tgctattacg aaaggattct ttgaagatga aggtataaag
      361 attgacctta taaataccca aggtgcagat aaaactatgg cagctttgat ttcaggtgaa
      421 gcaaacgtag gtttaatggg tcctgaagca tctatatatg tatataatca aaacaaaaac
      481 gattatgcag tgaactttgc tcaattgaca aaaagagatg gtagttttct agttgctagg
      541 aaaaaaatgc ctaatttctc ttacaatgat ttaaaaggaa cagaaatatt aggtggtaga
      601 aaaggtggag ttccactaat gacttttgaa tatgttctaa aagaaaaagg tcttactatt
      661 ggagaaaatc taaaagcagg caatgttaat gtaagaactg atgtacaatt tggtgtaatg
      721 gctggagctt ttgcaggtgg agagggtgac tttacaacag catttgaacc tacagcaaca
      781 gcaatggaaa aagaaggtag tggatatata gttacatcta taggaaaaga ttctggagaa
      841 atacctttta cagcatactc tactacgaga tcatacatga aaaacaataa agatttaatt
      901 caaagattta caaatgctgt ttataaaggt caattatggg ttcaacaagc atctagcaaa
      961 gaagtagcta aggctatgca acctttcttt gaagatatat ctttagaaga tttaacaaca
     1021 gttgtagata gatataaatc aatagatgca tggtctcaaa atcctgtatt aaaggaggaa
     1081 ggtttgaaga aattgatgac tgttatgaaa gaagctaaag aactagataa ggaagcacct
     1141 tataaagata tcgtaaatac tgagtttgca aacaatgcta taaaaaatat taaataaaat
     1201 atattagttt tagctagata ttttcttgtt tttataatga aaattaacaa aaatataaaa
     1261 agagcctttt aaaagactct ttttatattt gagattaaag tttatataat aaaatagata
     1321 ttaaagtact aactgtactt atatatctat cctctgtatt ctgctccagc attaattttt
     1381 gtaatttgaa cggctaccat ttcttcattg cttccattag taatttcatg ccactctcct
     1441 gttggtacaa atacagtatc gccgtttttt acatcacatt catgctcacc aagtttcatt
     1501 ttaccttctc cttttaggaa cacaaatatt tgttcaccat tagggtgtct atgagcatta
     1561 agaacttgat taggtttaaa ataataaact tctgaagtta tatcgttacc agcaaatact
     1621 ggtatttttg gaactgctgt atcattatat tgagctaagc ttccgtctaa tagattcttt
     1681 ttattttcat gcatactaga aatacctctt ttctatatta tagatttact attattatac
     1741 caatataaga aaatagtatt ctcactttac acaataggaa taaaattctt ttatttttaa
     1801 atata
//
LOCUS       DAMJYN010000223         1746 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.230, whole genome shotgun sequence.
ACCESSION   DAMJYN010000223 DAMJYN010000000
VERSION     DAMJYN010000223.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1746)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1746)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1746
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.230"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(99..1019)
                     /locus_tag="PC466_003777"
                     /pseudo
     CDS             complement(99..1019)
                     /locus_tag="PC466_003777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428810.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family isomerase"
     gene            complement(1308..>1746)
                     /locus_tag="PC466_003778"
     CDS             complement(1308..>1746)
                     /locus_tag="PC466_003778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDF2771102.1"
                     /translation="LNRNKARLKVARLQEHIANQRKDFLQKLSTKLIKENDIICIEDL
                     QVKNMIKNHKLSRSISDVSWSEFIRQLEYKANWYGRKIVKVGKFFASSQICNKCGYKN
                     EEVKDLSIREWICPSCNETHDRDINASINILKEGLRLITIQNK"
BASE COUNT          558 a          259 c          211 g          718 t
ORIGIN      
        1 atatattaac aaataataaa aaaattaatt tgattgtata taaattagtt tgttattaaa
       61 ttagtattaa aaagttcaaa aatttactta gaaagaatct ataattcgat ttctatgttt
      121 gttgagaatg caattacagc ttttccaatt atttttactt caactggctt attatctgaa
      181 ataattactt ttactaacat cttgcctttg cgttttattg cttctccttg aactgcttca
      241 aatataaact ctgtgttggg tataggtatt actttataat gtacaaggta cgcacctaaa
      301 ggtccattag catttcctgt aacagggtct tctgaaatac caattgcagg agcaaacatt
      361 cttccatgaa cttgtagagt ttctttatta tgtaatgtaa aaatataata tccattacat
      421 tttatttctt gacttatttt cgataattca tataaatttg gagataaact atttaatgtt
      481 gataattcct ttattccaat cataactttt gaatgtcctg tagatgatat ggcaatagga
      541 caatctgtac gaatatcttc atttaaaata ccaaatgcat taagtaatct tttttgatag
      601 gtttgttgta atggtggaga tacttcaatt tttccttgtg tcataattat ttcataatca
      661 ttatcttttt ttataatatc aactggtaat attccagcac cagttttttg aaatactgtt
      721 ttgttattga attggttttc tactgctcta acataatggg cagcaatagt agcatgacca
      781 catataggaa cttcattagt tggtgtaaaa aatctgatat gtacatcata attttcttga
      841 tgatttttag ccaatttatt gaaaataaaa gcagtttatg aattatttaa ttctcttgtt
      901 attttttgca tttgtgattc agataagcca tcagcatttg taattacacc agctggatta
      961 cctgtgaatc tttcttttgt aaatgagtca acttgataaa gacgaaattt tttattcata
     1021 ttatataatc ctttctaaac attagattag tttatctaca tagaaaactt gagataaatt
     1081 attatttatt attatctgtt taaataaaat taataaaata acatatgtct atattaaaat
     1141 ttaaaaatat acatctaaaa aagtagtatt atgtaaggct ctatgctaca ctgaacctcc
     1201 catgactaaa gtcacagggt tcctgcttca tagaattttg catactaaaa tatgtcttac
     1261 taattctcca caggctatcc ccgtagttcc tacggttctt acatacgtta tttattttga
     1321 attgttatta gtcttaatcc ttcttttaat atatttatac ttgcatttat atctctatcg
     1381 tgagtttcat tacaactagg acaaatccat tctcttatac ttaagtcctt cacttcctcg
     1441 tttttatacc cacatttatt gcatatttgt gaacttgcaa agaatttacc tacctttaca
     1501 atttttctac cataccaatt agccttgtac tctaattgac gaataaattc tgaccatgat
     1561 acatctgaaa ttgagcgaga tagtttatga tttttaatca tattctttac ttgtaaatct
     1621 tctatgcaaa taatatcatt ctcttttatt aatttagtag atagtttttg tagaaaatcc
     1681 tttctttgat tagctatatg ttcttgaagt cttgcaactt ttaatcttgc tttgtttcta
     1741 tttaaa
//
LOCUS       DAMJYN010000224         1632 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.231, whole genome shotgun sequence.
ACCESSION   DAMJYN010000224 DAMJYN010000000
VERSION     DAMJYN010000224.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1632)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1632)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1632
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.231"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            128..1564
                     /locus_tag="PC466_003779"
     CDS             128..1564
                     /locus_tag="PC466_003779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp28"
                     /protein_id="HDF2771103.1"
                     /translation="MKFYKRILTLTLSISFVFANIQLVDAISSVEKIQGKNKYEIAGK
                     IADKNAYKTAILINTSNSIADGLSASGLAGALNAPILLTEKNTIPTETSARLKNVSKV
                     YIIGGTYSISTSVENSLKSKKMKVVRIKGNDRIKTSYNVAKEINSIKKVNTVMLTNAY
                     KGEADAISIASVAARDKAPIILTNGQSIPFSTSGLKSYVIGGTASMSTTLVNNTKSTR
                     LGGSTRFETNKAIINKFYKDAREFYIAGAYELTNALVGSSLSKHGPIVLVNDGSNKSI
                     LKNAKKITSIGYIDSNIVQQCLNITNGIGDINTGVVKNVKPTTKTIKDGMYKVGKDIS
                     AGEYLITSNSGSYASYYEVTSDSTGNADSILSNDIFSGTRYITLKNGQYIKIEDSTMT
                     LAKYAKAQKAKNGKFGNGMYKIGLEIPAGEYIIMSNSSDAYYEVRNDSLGNAEGIVTN
                     DTFSGRRYITVEEGQYLILNDCYLIENE"
BASE COUNT          668 a          164 c          274 g          526 t
ORIGIN      
        1 gtattaatat ttatttgtaa tatgcttaat ataatttgca attttacata agtttgttaa
       61 gtacataact aatttaagaa tatgtattta tatattaaaa atttattatg agggggacaa
      121 ttttattatg aaattctata aaagaatatt aacattgact ttaagtattt cttttgtatt
      181 tgcaaatatt caattagtag atgcaatatc atctgtagaa aaaatacaag gaaaaaataa
      241 gtatgaaata gcaggcaaaa tagcagataa aaatgcatat aaaactgcta tattaattaa
      301 tactagtaac tctattgcag atggattaag tgcaagtgga ctagcaggag ctttaaatgc
      361 ccctatacta ttaactgaaa aaaatactat accaactgag acatctgcaa gattaaaaaa
      421 tgtatcaaaa gtttatataa ttggaggaac atattctatt agtacatctg tcgaaaattc
      481 attaaaatct aagaaaatga aagttgtaag aattaaggga aatgacagaa taaaaacaag
      541 ttataatgtt gcaaaagaaa taaattcaat aaaaaaagtc aatactgtta tgctaaccaa
      601 tgcatataaa ggagaagcag atgctataag tattgcatct gtagcagcaa gagataaagc
      661 accaataatt cttactaatg gacaaagtat acctttttca actagtggtt taaagtctta
      721 tgtaatagga ggaacagctt caatgagtac cactttagta aacaatacta aatctactag
      781 actaggaggg agtactcgtt ttgaaactaa taaagcaata ataaataagt tttataagga
      841 tgctagagag ttttatatag ctggagctta tgaattaaca aatgcacttg taggatcttc
      901 tttatcaaaa catggtccaa tagttttagt taatgatggt agcaataaaa gcattttaaa
      961 aaatgctaag aagataactt ctataggata tatagattca aatatagtac aacagtgttt
     1021 aaatataaca aatggaattg gagatattaa tactggggtt gtaaaaaatg ttaaacctac
     1081 tacaaagact ataaaagatg gaatgtataa ggttggaaaa gatatatcag caggtgaata
     1141 cttaattact tcaaactcag gaagttatgc ttcttattat gaagttacaa gtgatagtac
     1201 aggtaatgct gatagtatac tttcaaatga tatttttagt gggactagat atatcacctt
     1261 aaagaatggt caatatatta aaattgagga ttcaacaatg acattagcaa agtatgctaa
     1321 agcccagaag gccaagaatg gtaagtttgg aaatggtatg tataaaattg gattagaaat
     1381 tcctgctgga gaatatatta taatgtcaaa ttcttctgat gcatattatg aagttagaaa
     1441 tgatagctta ggtaatgcag agggaatagt tactaatgat actttttcag gaagaagata
     1501 tataacggtt gaggaaggtc aatatttaat attaaatgat tgttatttaa ttgaaaatga
     1561 atagatgtaa ttgtatttaa tagtaaatca tatattttat ttaaggaaag atgttttaag
     1621 ttttaattta aa
//
LOCUS       DAMJYN010000225         1588 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.232, whole genome shotgun sequence.
ACCESSION   DAMJYN010000225 DAMJYN010000000
VERSION     DAMJYN010000225.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1588)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1588)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1588
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.232"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            37..510
                     /locus_tag="PC466_003780"
     CDS             37..510
                     /locus_tag="PC466_003780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2771104.1"
                     /translation="MFKEYLIRELKEDDIKNALDLIWNVFEEFESPDYCDEGITTFHQ
                     FIEYNSIIEKIKEKTLFFWGCFDSKKLIGVLAIRNLNHICMLFVDKNYHKHGVAKKLM
                     TTGIQYCICNKFNLTEITVNSSPYAVEVYHKLGFEDIAVEQIVDGIRFTPMKLLI"
     gene            complement(879..1436)
                     /locus_tag="PC466_003781"
     CDS             complement(879..1436)
                     /locus_tag="PC466_003781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2771105.1"
                     /translation="MRVSREIVIQATSDIVNKDGLNKVSLKVIAEKLGIRTPSLYNHI
                     ESLDDLLLEVAHKGMREMNSQMIKATIGNFGDTAIKCISIAYFNFIISNPGVYETIQW
                     ATWHGNNETLEIFDEYKSLLEKLILSCNLNTKNTGEVLNLIMSVLHGYSTLQLGKSLL
                     SKEEAIKGLADSIDTVLLGIHKKYD"
BASE COUNT          573 a          207 c          174 g          634 t
ORIGIN      
        1 attataatta aaataataat aaaggtgttg tttataatgt tcaaagaata cttaataaga
       61 gaattaaaag aagatgatat taaaaatgca ttagacttaa tctggaatgt atttgaagaa
      121 tttgaatctc cagattattg tgatgaagga attacgacat ttcatcaatt tatagaatat
      181 aattctatta ttgaaaaaat caaagaaaaa acactcttct tttggggttg ttttgactct
      241 aaaaaactta ttggagtctt agctattaga aatttaaatc atatatgtat gttatttgta
      301 gataaaaact atcataaaca tggtgttgca aaaaaattaa tgactacagg catacaatac
      361 tgtatttgta ataaatttaa tttaactgaa ataactgtaa attcatcacc ttatgctgtt
      421 gaagtttatc ataaattagg atttgaagat attgctgttg agcaaattgt tgacggtata
      481 cgttttacac ctatgaaatt gttaatataa taaattaaat aaaaagcaaa gtctcttaaa
      541 tattttatag ttactttgct tttaaaccaa gatttaaaat aatactatct tttttgtttt
      601 ttaataatat actttaaaag ccttactaat atgaactata atttattttt tgatatcctt
      661 tttgattaac atataaatta attcaattat taaacataaa ctatgttgtt tctctttata
      721 tctcttcttt gtaaacaata ttgggcattt gaaaataaat attcttaaaa tatactgttc
      781 tcctgttgat tttcctttgg tacaaatgat aaaattttaa tttacatgct ccgtaatgaa
      841 gtgtttaata aataagttaa aataatttat ttacctcctt aatcatattt tttatgaata
      901 cctaataaca cagtatcaat agaatcggct aaacctttta tagcttcttc tttactcaaa
      961 agtgatttcc caagttgcaa agtcgaataa ccatgaagta cactcattat taagtttaat
     1021 acttcacctg tattctttgt atttagatta caagaaagaa taagtttttc taataaggat
     1081 ttatattcat caaagatttc taatgtttca ttatttccat gccaagtagc ccactgaatt
     1141 gtttcataaa caccaggatt agaaattata aaattaaagt atgctatact tatacacttt
     1201 atagctgtat ctccaaaatt tccaatagtc gcctttatca tttgactatt catctctctc
     1261 attcctttat gagctacttc aagtaataaa tcatctagac tttctatatg attgtacaaa
     1321 gatggtgtac gtattcctag cttttctgca ataactttta aagaaacttt gttaagccca
     1381 tctttattaa ctatatctga tgtagcttgt ataactattt ctctactaac acgcatgatt
     1441 ttccctcttt catttaaaat taattacttt attagtttag ctaatctaat tagtttcgtc
     1501 aattattgta atttataaaa ttctttatac tcttataaaa tcttgacagt ttaattataa
     1561 tttaatataa tactaattga attagttt
//
LOCUS       DAMJYN010000226         1542 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.233, whole genome shotgun sequence.
ACCESSION   DAMJYN010000226 DAMJYN010000000
VERSION     DAMJYN010000226.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1542)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1542)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1542
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.233"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(<1..>1542)
                     /locus_tag="PC466_003782"
     CDS             complement(<1..>1542)
                     /locus_tag="PC466_003782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_046462978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="fibrinogen-binding adhesin SdrG C-terminal
                     domain-containing protein"
                     /protein_id="HDF2771106.1"
                     /translation="NDDSASEAPDYVGVNSDSLENSTLENGDDESSNDQDKDIAYATP
                     AEATAPRSIEPRSRVALNETQAQKQGKNVNDLITVTNQSITEGGREDGIISAHDGENI
                     TYTTDFKIDNDVKSGDTMTVKYDPRTVPSDLTDDHTPVDIMDPSGEVIATGSFDNTNK
                     TSTYTFTDYVDKYENVNAKLVMNSFIDKKEVPNEETVDLTFATANEPINKTFNVSYQR
                     PIVERASNIQSIFSQLDLDDNTVEQTVYVNPLSLNAQNAKVLIRGAGVYNDGGFFNGE
                     GSTIIDNSTDIKVYKAKPDQKLPQSNRIYDYSQYEDVTNQVNIDKNYSNNQAMVDFGN
                     INSPYIIKVKSKYTPGAEDSLAIQQGVRMTTTNDGILSYAGYTNSIISTNDQGGGNGE
                     EAPEQTYKIGDYVWEDVDKDGVQGTDEKEKPISNVLVTLTYPDGTSKSVKTDENGHYE
                     FDNLYDGETYQVSFETPEGYTPTKINVGDGSLDSNGGSVTVTIDGHDDMTLDSGFYKD
                     DTDAD"
BASE COUNT          452 a          291 c          215 g          584 t
ORIGIN      
        1 cgtcagcatc tgtatcatct ttatagaaac cactatctaa agtcatgtca tcatgaccgt
       61 caatagttac agttactgat ccaccatttg aatctaacga accatctcca acattaattt
      121 tagttggtgt ataaccttca ggtgtttcaa atgaaacttg atatgtttca ccatcatata
      181 aattatcaaa ttcataatgt ccattttcgt ctgttttcac tgattttgaa gtgccatctg
      241 gataagttaa tgttactagt acgttactga ttggtttttc tttttcatct gtaccttgaa
      301 caccatcttt gtcaacatct tcccatacat agtcacctat tttatatgtt tgctcaggcg
      361 cctcttctcc attacctcca ccttggtcat tagtactaat aatactattc gtataaccag
      421 cataagataa aataccatca ttagttgttg tcattctaac accttgttgt attgctaaac
      481 tatcctctgc tccaggtgta tatttacttt tcaccttgat gatataaggt gaatttatat
      541 ttccaaaatc aaccatagct tgattattag aataattttt atcaatattc acttgatttg
      601 ttacatcttc atattgacta taatcataaa ttctattact ttgcggtaat ttttggtctg
      661 gtttagcctt atatacttta atatcagtgc tattgtctat aatagtgcta ccctcaccat
      721 tgaaaaatcc accatcatta tacacgcccg cacctctaat taaaacttta gcgttttgag
      781 catttaaact aagtggattc acataaactg tttgttctac agtgttgtcg tctaaatcta
      841 actgtgaaaa aatagattga atattcgacg cacgttcaac aataggtcgt tggtaactaa
      901 cattaaaagt tttatttatt ggctcattag cagttgcaaa tgttaaatct actgtttctt
      961 catttggcac ttctttttta tcaataaaag aattcataac taattttgca tttacatttt
     1021 catacttatc aacgtaatct gtaaaagtgt aagtggatgt tttattagta ttatcaaatg
     1081 atcctgtagc aataacttct cccgatggat ccataatatc aactggtgta tggtcatctg
     1141 ttaaatcaga aggaacagtt cgaggatcat attttacagt catggtatct ccagatttta
     1201 catcattatc gattttaaaa tcagtagtat aagtgatgtt ttcaccatca tgagcactga
     1261 ttataccatc ttctctccca ccttcagtaa ttgactgatt agttactgta attaaatcat
     1321 taacattttt accctgcttt tgtgcttgag tttcatttaa tgcaactcta gaacgaggtt
     1381 caatagaacg tggtgctgtt gcttctgcag gtgttgcata agcaatatct ttatcttggt
     1441 cattagatga ttcgtcatcg ccattttcta aagttgagtt ttctaaagaa tcagaattaa
     1501 ctccaacata atcaggtgct tcacttgctg aatcgtcatt tg
//
LOCUS       DAMJYN010000227         1493 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.234, whole genome shotgun sequence.
ACCESSION   DAMJYN010000227 DAMJYN010000000
VERSION     DAMJYN010000227.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1493)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1493)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1493
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.234"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            105..1343
                     /locus_tag="PC466_003783"
     CDS             105..1343
                     /locus_tag="PC466_003783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conserved phage C-terminal domain-containing
                     protein"
                     /protein_id="HDF2771107.1"
                     /translation="MNKGFYKLNSVVLNFDIKNDVNKIRFNHYIMRKENIQRLQGTLP
                     NGQFYMTVRRAATDLQLSISTISRLVKEFLDLGIIRLVSKGVKGNRSVYSYVSIEFNG
                     SLFDDSKYMELDCVCNDEFIDNSGIEFDCDSKDNSFNGDINVETVHCINEYFSDDDVE
                     HNYNNFHNKDTIKDKAISNISTIKKYIDESFDTNKSENSNLQQESINFNFNDTCNEID
                     KRTNNSIENNQNKRPMRLSDISVLSDKGMTNKKNYFNHNHGIQKRNKSATKKKESLNK
                     FNKKNIQQSIINMLNKKSGKNFKIDSPISIKLINERLKEGYVLEDFYKVIEVKVAKWK
                     NTIMEMYIRPETLFSYKFESYVNENISMKSQSNVHPCKEGNSNDSSNYIHSDYTTYDG
                     SVRERKKYENVRYWNPICEI"
BASE COUNT          637 a          135 c          252 g          469 t
ORIGIN      
        1 aatattaaaa aaatatatat atttatattt aaactatttt gttatttata taaaaatact
       61 tatctagtta ctagcaatta ttagtagaaa tgggggaaat agagatgaat aagggatttt
      121 acaaattaaa ttcagtggta ttgaactttg atattaagaa tgatgttaac aagataagat
      181 ttaatcatta tataatgaga aaagaaaaca tacaaagact tcaaggaact ctgccaaacg
      241 gacaatttta tatgacagtg agaagagctg ctacagattt acaactttct atttctacta
      301 taagtaggct tgtaaaagag tttttggatt tagggataat aagattagtg tctaagggtg
      361 taaaaggtaa tcgttctgta tatagttacg taagtataga gtttaatgga agtttatttg
      421 atgatagcaa atatatggaa cttgactgtg tatgtaatga tgaatttatt gataatagtg
      481 gcatagagtt tgattgtgat agcaaagata attcttttaa tggagatata aatgtagaaa
      541 ctgtgcattg cattaatgag tatttctctg atgatgatgt agagcataat tataacaatt
      601 tccataataa agatactata aaggataaag ccatttctaa tattagcact atcaaaaaat
      661 atattgatga atcttttgat acaaataaat cagaaaattc taacttacaa caggagtcaa
      721 taaatttcaa ctttaatgat acatgcaatg aaatagataa aagaacgaat aatagtatag
      781 aaaataatca aaataaaagg cctatgagat tgagtgacat cagtgtttta agtgataaag
      841 gtatgacaaa taaaaagaat tactttaatc ataatcatgg tatacaaaaa aggaataaat
      901 ctgcaacaaa gaaaaaagaa tccttaaata aatttaataa aaaaaatata cagcaaagca
      961 ttataaatat gctaaataaa aaatcaggta agaattttaa aatcgattct ccaataagca
     1021 taaaacttat caatgaaagg ctaaaggagg gctatgtctt agaagatttc tataaagtta
     1081 ttgaggtaaa agtggctaag tggaaaaata ccataatgga aatgtatata agaccagaaa
     1141 ccttgtttag ctataagttt gaatcctatg taaatgaaaa catatctatg aaaagtcaaa
     1201 gtaatgttca tccatgtaaa gaaggcaata gtaatgatag cagtaattat atacattctg
     1261 attatacaac atatgatggc agtgtgcgtg agagaaaaaa atatgagaat gtaagatact
     1321 ggaatcctat atgtgaaatt taattagttt aagaatgtat ttatgataaa taagatatta
     1381 atagagaata gtgagctata gcaaatgata tatcaatagt tggtagtaag ttatattaag
     1441 caagatatta ctatcaggta gtgaattata gtgaacgata tatcaataat tgg
//
LOCUS       DAMJYN010000228         1438 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.235, whole genome shotgun sequence.
ACCESSION   DAMJYN010000228 DAMJYN010000000
VERSION     DAMJYN010000228.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1438)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1438)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1438
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.235"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            67..348
                     /locus_tag="PC466_003784"
     CDS             67..348
                     /locus_tag="PC466_003784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2771108.1"
                     /translation="MASKQTPRNNLEKFLRIRVLSHTGDKIHIKLPVNFAKRMIENNA
                     LDLFNGKDDVVDGKKVTEILVKAFDYDLTGEVVHLERKNGDIIKVSIVQ"
     gene            612..866
                     /locus_tag="PC466_003785"
     CDS             612..866
                     /locus_tag="PC466_003785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2771109.1"
                     /translation="MENKDFKLTICIFAFVIGVVVLFCCIGLGEFSAEHIIQQNGGIM
                     DTDQYNIYLDQSISQYRNFGSILALLGGIGILFDKYIRKY"
     gene            911..1234
                     /locus_tag="PC466_003786"
     CDS             911..1234
                     /locus_tag="PC466_003786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2771110.1"
                     /translation="MATEIFTVKITPLEAQKMIKENIDADLVFSDSYNLGDDKFILIT
                     TFEKYYARNNSDAGLIVVYENTTEKTVIKATSTGSAIGVLKIDWGAGGNLLKRVKNIL
                     AEYII"
BASE COUNT          603 a          106 c          229 g          500 t
ORIGIN      
        1 tataaagata tttttaagaa taaaatttat tattaaataa aaaataaagg agagtgattt
       61 aatcgtatgg catcaaaaca aacaccaaga aacaatttag aaaagttttt aagaataaga
      121 gtcttatcac atacaggcga taaaatacat ataaagttac ctgtaaattt tgcaaaaaga
      181 atgattgaga ataatgcttt ggatttattt aatggaaaag atgatgtagt agatggtaaa
      241 aaggttactg aaatattagt caaagcattt gactatgatt taactggaga agtagttcac
      301 ttggagagaa aaaatggaga tattattaaa gtttcaattg tacaatagaa ttattttata
      361 tgaattttat ttttgaatag ttataaataa ttagaaattt gtaaaaaagt ataatatatt
      421 attagtaatg gtgcagaata cacatttata atttatagat gtgtattttt tgtttaaaaa
      481 atttaaatat ataaaactat aaaggttaca attttggaaa tagatgtaaa tatatgttct
      541 attgtataat aagagtaata taaaatctag taaaaataat caaataaatt taacttatga
      601 gagggataac tatggaaaat aaggatttta aattaacaat atgtatattt gcttttgtaa
      661 ttggagtagt agtattattc tgctgtatag gtttgggtga atttagtgca gagcatatta
      721 ttcaacaaaa tggtggaatc atggatactg accaatataa tatttatcta gaccaatcta
      781 tttctcaata tagaaatttt ggttctatat tagctctgtt aggaggaata gggatattgt
      841 ttgataaata tatcagaaaa tactagagat tatgttttgt ctaaaataaa ttcttatgag
      901 gagataaaaa atggcaacag aaatatttac tgtaaaaatt acacccttag aagcacaaaa
      961 aatgataaaa gaaaatattg atgcagattt agtttttagt gattcttata atttaggaga
     1021 tgataaattt atactaatta caacttttga gaagtattac gcaagaaata atagtgatgc
     1081 aggattaatc gtagtttatg aaaataccac agaaaaaaca gttattaaag ctacttcaac
     1141 aggcagtgca attggagttt taaaaattga ttggggtgca ggtggaaatt tacttaaaag
     1201 agtaaaaaac atacttgctg aatatattat ttaattattt tatctaactg ataatatgtc
     1261 aagaaaatct cgtaaaagag gttaagaata tttttataat atatagataa ataaggattt
     1321 gaaggtaaag tttttaatgt ataaagaaaa ataatataat aaaacgaatt ggctttataa
     1381 ttctttataa ggcaaagagt acatttcttt atataattgt tggatattaa ataatatg
//
LOCUS       DAMJYN010000229         1336 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.236, whole genome shotgun sequence.
ACCESSION   DAMJYN010000229 DAMJYN010000000
VERSION     DAMJYN010000229.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1336)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1336)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1336
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.236"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            27..101
                     /locus_tag="PC466_003787"
     tRNA            27..101
                     /locus_tag="PC466_003787"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:59..61,aa:Thr,seq:tgt)
     gene            116..200
                     /locus_tag="PC466_003788"
     tRNA            116..200
                     /locus_tag="PC466_003788"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:150..152,aa:Tyr,seq:gta)
     gene            209..292
                     /locus_tag="PC466_003789"
     tRNA            209..292
                     /locus_tag="PC466_003789"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:243..245,aa:Leu,seq:tag)
     gene            322..398
                     /locus_tag="PC466_003790"
     tRNA            322..398
                     /locus_tag="PC466_003790"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:356..358,aa:Arg,seq:tct)
     gene            406..481
                     /locus_tag="PC466_003791"
     tRNA            406..481
                     /locus_tag="PC466_003791"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:439..441,aa:Gln,seq:ttg)
     gene            570..658
                     /locus_tag="PC466_003792"
     tRNA            570..658
                     /locus_tag="PC466_003792"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:604..606,aa:Ser,seq:tga)
     gene            662..737
                     /locus_tag="PC466_003793"
     tRNA            662..737
                     /locus_tag="PC466_003793"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:695..697,aa:Phe,seq:gaa)
     gene            744..817
                     /locus_tag="PC466_003794"
     tRNA            744..817
                     /locus_tag="PC466_003794"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:778..780,aa:Met,seq:cat)
     gene            832..908
                     /locus_tag="PC466_003795"
     tRNA            832..908
                     /locus_tag="PC466_003795"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:866..868,aa:Ile,seq:cat)
     gene            932..1008
                     /locus_tag="PC466_003796"
     tRNA            932..1008
                     /locus_tag="PC466_003796"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:966..968,aa:Pro,seq:tgg)
     gene            1016..1092
                     /locus_tag="PC466_003797"
     tRNA            1016..1092
                     /locus_tag="PC466_003797"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1050..1052,aa:His,seq:gtg)
     gene            1101..1176
                     /locus_tag="PC466_003798"
     tRNA            1101..1176
                     /locus_tag="PC466_003798"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1134..1136,aa:Lys,seq:ttt)
     gene            1184..1257
                     /locus_tag="PC466_003799"
     tRNA            1184..1257
                     /locus_tag="PC466_003799"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1216..1218,aa:Cys,seq:gca)
     gene            1264..1335
                     /locus_tag="PC466_003800"
     tRNA            1264..1335
                     /locus_tag="PC466_003800"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1296..1298,aa:Asn,seq:gtt)
BASE COUNT          320 a          310 c          355 g          351 t
ORIGIN      
        1 ccccttccag gtcgccaaaa taaaatgctg gtgtggctca acggtagagc agctgacttg
       61 taatcagcag gttgtaggtt cgattcctat caccagctcc atgtaaaatt aatacggagg
      121 atttcccgag cggccaaagg gggcagactg taaatctgtt gtcatcgact tcggtggttc
      181 gaatccacca tcctccacca aaaaatgcgc ggatgtggcg gaattggcag acgcactaga
      241 cttaggatct agcgccattg gcgtgggggt tcgactccct tcatccgcac catttttgtt
      301 tgatatacat atataaattg tgggtgcata gctcagctgg atagagcaac gcccttctaa
      361 ggcgtgtgtc cggggttcga atccctgtgc gctcaccaca tatattgggg attagccaag
      421 tcggtaaggc acatgacttt gactcatgta tgcgtaggtt cgagtcctgc atccccagcc
      481 aaatgatgta ttactaagct atatttgaac tatttttatt ttaaatatag ttaggttcaa
      541 ttttagaata agtttaagta tccgaatgtg gagaggtgtc cgagtggttt aaggagctgg
      601 tcttgaaaac cagtgacttc gaaaggggcc gtgggttcga atcccaccct ctccgccaaa
      661 tgcccagata gctcagtcgg tagagcaggg gactgaaaat ccccgtgtcg gtggttcgat
      721 tccgcctctg ggcaccaaaa tatggcggta tagcttagtt ggctagagcg ttcggttcat
      781 acccgaaagg tcataggttc gactcctatt accgctacta aaatttaatg tgggccatta
      841 gctcagttgg ttagagcgcc cggctcataa ccggtaggtc tggggttcga gtccctgatg
      901 gcccaccaca ttaaattaat taatataaat tcgaggtgta gcgcagtttg gtagcgcaca
      961 tggtttggga ccatggggcc gggggttcga gtcccttcac ctcgaccaat ataaggtggg
     1021 tatagctcag ttggttagag cgccagattg tggctctgga ggtcgtgagt tcgactctca
     1081 ttatccaccc caattcatat ggtctattag ctcagtcggt agagcacctg acttttaatc
     1141 agggtgtccc gcgttcgagt cgcggataga tcaccaaaaa ggtggcgaca tagccaagtg
     1201 gtaaggcagt ggactgcaac tccttgatcc ccagttcgaa tctgggtgtc gcctccaaaa
     1261 tattccaagg tagctcaacg gtggagcaac cggctgttaa ccggtaggct gtgggttcga
     1321 gccccaccct tggagc
//
LOCUS       DAMJYN010000230         1279 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.237, whole genome shotgun sequence.
ACCESSION   DAMJYN010000230 DAMJYN010000000
VERSION     DAMJYN010000230.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1279)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1279)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1279
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.237"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            176..1252
                     /locus_tag="PC466_003801"
     CDS             176..1252
                     /locus_tag="PC466_003801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--glyoxylate aminotransferase family
                     protein"
                     /protein_id="HDF2771111.1"
                     /translation="MSKKLFIPGPIDVKEEVLQKMATPMIGHRGKDASMLQKSISEKM
                     QKLFYTNNTILLSTSSGTGLMEGSIRSCTSKKAAVFSCGSFGDRWYKMAVANNVPADI
                     FKVELGEATTPEMVDKVLSTGEYDLITVTHNETSTGIRNPIEEIGEVVKKYEDVIYCV
                     DTVSSAGGIKVEVDKIGIDICITSVQKALGLPPGMSICTFSQKAIDRAKQVPFRGVYL
                     DLLAMYEYLIKKNYQYPSTPSLSHMFALDFQLDNILDEGLDNRFNRHEDMANLVRNWA
                     KKHFQIFTNENHLSNTLTVIENTQGISVSNLNSKLQERGFQIANGYGDLKEKTFRISH
                     MGDYTVEDVQELLDNIDDILGFNK"
BASE COUNT          505 a          177 c          223 g          374 t
ORIGIN      
        1 attcagactt atgaaaaggc agaaaatgaa tgttttcata aaatatataa aataaattat
       61 atataaaaaa taaattttat gttgacatag ttaattcagc ttgatattat agttattaaa
      121 aataaggaca gtaaaaacgc tatccatatt acaaactaaa aaggggggaa ttataatgag
      181 taagaaatta tttattcctg gtcctattga tgttaaagaa gaagtcttgc aaaagatggc
      241 tacaccaatg ataggacata gaggaaaaga tgcatctatg ctccaaaaga gtataagtga
      301 aaagatgcaa aaactattct atacaaacaa cacgatactt ttatccacgt catccggaac
      361 tggtttaatg gaaggctcca ttcgttcctg tacatccaaa aaggcagcag tattttcctg
      421 tggatccttt ggtgatagat ggtacaaaat ggcagtggct aataatgtcc cagcggatat
      481 atttaaagtt gaattaggag aggcaacaac gccagaaatg gttgataagg tgctttctac
      541 cggagaatac gatttaataa ctgtaactca caatgaaact tcaactggaa taagaaatcc
      601 aatagaagaa attggagaag ttgttaaaaa gtatgaagat gtaatctact gtgtagatac
      661 tgtaagttca gccggtggaa taaaagtcga ggttgataag attggaatag atatttgtat
      721 aacatcagta caaaaagcac tgggattacc accaggaatg tctatttgca cattttctca
      781 aaaagcaatc gatagagcta agcaagtacc ttttagagga gtatatcttg atttgttagc
      841 aatgtatgaa tacttaatca agaaaaacta ccaataccct tcaacaccat ctctttctca
      901 catgttcgct ttagatttcc aattagataa tatattagat gaaggcctag ataacagatt
      961 caacagacat gaagacatgg caaacttagt tagaaactgg gctaaaaaac acttccaaat
     1021 ttttaccaat gaaaatcact tatccaatac acttactgtt atagaaaata ctcaaggtat
     1081 tagtgtatca aatttaaatt caaaattaca agaacgagga ttccaaatag caaatggcta
     1141 tggagattta aaagaaaaaa cttttagaat ttcacatatg ggtgactata ctgtcgaaga
     1201 tgtacaagaa ttattagata atattgatga tatattaggt tttaataaat aatattgtaa
     1261 aaatatgtat gttttaaga
//
LOCUS       DAMJYN010000231         1214 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.238, whole genome shotgun sequence.
ACCESSION   DAMJYN010000231 DAMJYN010000000
VERSION     DAMJYN010000231.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1214)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1214)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1214
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.238"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(354..554)
                     /locus_tag="PC466_003802"
     CDS             complement(354..554)
                     /locus_tag="PC466_003802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000809131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HDF2771112.1"
                     /translation="MNNGIVKWFNNEKGFGFISMESGDDVFAHFSAIQTSGFKSLEEG
                     QKVSFDIVKGARGPQAENITIL"
     gene            complement(779..955)
                     /locus_tag="PC466_003803"
     CDS             complement(779..955)
                     /locus_tag="PC466_003803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2771113.1"
                     /translation="MFRDKMDKCTHMLTAYIGSSYDYCDFIDTQLDDFILEYGEKVVE
                     SCLHQVMVLVSKYN"
     regulatory      complement(1009..1098)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
BASE COUNT          457 a          169 c          119 g          469 t
ORIGIN      
        1 aaatagaaca ttgaaacata tagatatgtt ttaattgctt tttattaaca aattactaaa
       61 agtgttatat cagaattgaa tacaaaagaa agagtatgta tttatgagat agttgaaaat
      121 tttgatgtgc cacaactaaa attattatat tactatatat tctaattaaa agagtacttg
      181 taggtttaag tacatacttt ataaatatat ttttgtcaga tttattttat aaaaagtatt
      241 tagactaagt attattttta agtattttct tgttgaagtt attttttcct tttttacaaa
      301 atgcgtaaat aaaaaaaaga ctcttaaaag agtctttccg aaaaatctat atattataat
      361 atagttatat tttctgcttg aggacctcta gcgcctttaa ctatatcaaa gcttactttt
      421 tgaccttctt ctaatgattt aaatcctgaa gtttgtatag ctgagaaatg agcaaatacg
      481 tcatctccac tttccattga tataaatcca aatccttttt cattattaaa ccattttact
      541 attccattat tcattaaaaa tactcctatt aacctatatc aagatatact tgatttactt
      601 gtgtattacc acaaatacta ttatatcata gattaacata aatgtctatt taattataat
      661 ttttagttaa catttttatt tattcttaat atgaaaataa atttaaacat tttatattac
      721 caatatatta atgtaaatgt agataaaact aaaaagggtt ttctagaaga aaatctgtct
      781 aattatactt acttaccaat accatcactt gatgcaagca agattccaca actttttctc
      841 cgtactctaa tataaaatca tctaactgtg tatctataaa atcacaataa tcatatgaac
      901 taccaatata agcagttagc atatgtgtac atttatccat tttatctcta aacataatgt
      961 atttatcccc ctaaaaaact ttcatgaaaa acaaaaagaa aatatctttt tggcaactgg
     1021 ctgacataac ttattttata agcgttagtc cctatagctt tgcgtcacta aatttctcta
     1081 gttttgccga tttagtttta ttctacagat taataataca atagaattag ctattattca
     1141 acatatctag ctgaaaaatt aataaattta tatatgaacg ttaaattatt tgaaaaaata
     1201 aaaagcccct ctgt
//
LOCUS       DAMJYN010000232         1213 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.239, whole genome shotgun sequence.
ACCESSION   DAMJYN010000232 DAMJYN010000000
VERSION     DAMJYN010000232.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1213)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1213)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1213
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.239"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            394..906
                     /locus_tag="PC466_003804"
     CDS             394..906
                     /locus_tag="PC466_003804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2771114.1"
                     /translation="MKVKKFKSGIVMALTVMAIGASLTNVSAMELNKSKEFETKYNEM
                     KRDFQEDYGKEDKFNITLDDEFTKEEVNGAKGIIKTTNKMNNEVVVLNYFDEMKSGIE
                     FELKAKAEKNAILRDEFQQGYGKEDKFKVVLDDEFTKEEVNGAKGIIKTTDKETGEVI
                     VYNYFDELEK"
BASE COUNT          543 a           85 c          209 g          376 t
ORIGIN      
        1 tacttatttt tagaatattc agtaaaataa ttttgatata ctctatatat tttgtatgtt
       61 aaaagtaaat aaattattgt taaagaatgt aaagactttt aaatttttta tcacaggatt
      121 ttaagtaaat aagaaggatt ggagtaatta aaaattttta ttttgcaaaa ataagtattt
      181 atttatatgg ataaatttga ttttaaatct atcaatatag ataaaatctt attatttaac
      241 ttcaactatt ccttaaaaaa gcaactttta aggaatagtt gaaacaaaaa gtttggttac
      301 ataatagtaa ttttagttac aagaatgaaa ctgtaaaact taggattttc tttatataat
      361 ttcattgaga acatttaatt taggaggtaa ggtatgaaag taaaaaaatt taaaagtggt
      421 atagtaatgg cattaacagt aatggcaatt ggagcatcat tgacaaatgt atcagctatg
      481 gaattaaaca agagtaaaga gtttgaaact aaatacaatg aaatgaagag ggattttcaa
      541 gaggattatg gaaaagaaga caaatttaat ataacattgg atgatgaatt tacaaaagaa
      601 gaagtaaatg gagctaaagg gattataaag acaactaata aaatgaataa tgaggttgta
      661 gtattaaatt attttgatga aatgaaatct gggattgaat ttgagttgaa ggcaaaagca
      721 gaaaaaaatg caattttgag agatgaattt caacaaggtt atggaaagga agataaattc
      781 aaagttgtgt tagatgatga atttacaaaa gaagaggtaa atggagctaa gggcattata
      841 aagactacag ataaagagac aggtgaggtt atcgtatata attactttga tgagcttgaa
      901 aaataatgct taaagattac tttgattgaa tgaaaaggta attgtgttga gaatattaaa
      961 tgactgaata aaaacagttg tatcaaaaac aaacaataat agaatgtaag aatgattgtg
     1021 tcgaaaatat taaatgactg aataaaaaat agttgcgtca aaaacaaaca ataatagaat
     1081 gtaagaatga ttgtatcaag aatataaaat gattcaacaa aaaacgattg tgttaaaaac
     1141 aaacaacaat agaatgtaag aatgattgta tcaagaatat aaaatgactg aataaaaacg
     1201 attgcgtcaa aaa
//
LOCUS       DAMJYN010000233         1146 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.240, whole genome shotgun sequence.
ACCESSION   DAMJYN010000233 DAMJYN010000000
VERSION     DAMJYN010000233.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1146)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1146)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1146
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.240"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            <1..>1146
                     /locus_tag="PC466_003805"
     rRNA            <1..>1146
                     /locus_tag="PC466_003805"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          293 a          253 c          352 g          248 t
ORIGIN      
        1 caggatggac ccgcgtctga ttagctagtt ggtaaggtaa cggcttacca aggcgacgat
       61 cagtagccga cctgagaggg tgatcggcca cattggaact gagacacggt ccaaactcct
      121 acgggaggca gcagtgggga atattgcaca atgggcgaaa gcctgatgca gcaacgccgc
      181 gtgagtgatg aaggccttcg ggtcgtaaaa ctctgtcctc aaggaagata atgacggtac
      241 ttgaggagga agccccggct aactacgtgc cagcagccgc ggtaatacgt agggggctag
      301 cgttatccgg atttactggg cgtaaagggt gcgtaggcgg tctttcaagt caggagtgaa
      361 aggctacggc tcaaccgtag taagctcttg aaactgggag acttgagtgc aggagaggag
      421 agtggaattc ctagtgtagc ggtgaaatgc gtagatatta ggaggaacac cagttgcgaa
      481 ggcggctctc tggactgtaa ctgacgctga ggcacgaaag cgtggggagc aaacaggatt
      541 agataccctg gtagtccacg ctgtaaacga tgagtactag gtgtcggggg ttaccccctt
      601 cggtgccgca gctaacgcat taagtactcc gcctgggaag tacgctcgca agagtgaaac
      661 tcaaaggaat tgacggggac ccgcacaagt agcggagcat gtggtttaat tcgaagcaac
      721 gcgaagaacc ttacctaagc ttgacatccc aatgacatct ccttaatcgg agagttccct
      781 tcggggacat tggtgacagg tggtgcatgg ttgtcgtcag ctcgtgtcgt gagatgttgg
      841 gttaagtccc gcaacgagcg caacccttgt ctttagttgc catcattaag ttgggcactc
      901 tagagagact gccagggata acctggagga aggtggggat gacgtcaaat catcatgccc
      961 cttatgctta gggctacaca cgtgctacaa tgggtagtac agagggttgc caagccgtaa
     1021 ggtggagcta atcccttaaa gctactctca gttcggattg taggctgaaa ctcgcctaca
     1081 tgaagctgga gttactagta atcgcagatc agaatgctgc ggtgaatgcg ttcccgggtc
     1141 ttgtac
//
LOCUS       DAMJYN010000234         1142 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.241, whole genome shotgun sequence.
ACCESSION   DAMJYN010000234 DAMJYN010000000
VERSION     DAMJYN010000234.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1142)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1142)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1142
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.241"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            47..304
                     /locus_tag="PC466_003806"
     CDS             47..304
                     /locus_tag="PC466_003806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2771115.1"
                     /translation="MIIIRSQDKTNLMQINQIKIDGSQVYAVFESKIDTVKIGDYENN
                     TRAIQVLDNIQNFIENGTKYDYITSNKVRYNVNKIFQMPAK"
     gene            complement(414..1094)
                     /locus_tag="PC466_003807"
     CDS             complement(414..1094)
                     /locus_tag="PC466_003807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HDF2771116.1"
                     /translation="MIWTFYSFICVILPCLIYQIVVIKRKNLKVEKNVMIHLVWVYIF
                     LLYIYLALSKAGIGSIWDIGRYSGLFRIDEINLIPFDSVGILTYILNIIMFMPLGFLL
                     PLIWKNFRNIINVSLTGLGFSLAIELCQLFNLRATDIDDLMMNTLGAVLGYFIWVGVN
                     NLFNLIKKKDIFPSIYKNIIQDEIAITIDDDISKKITSLYKNEAIIYLILAVLGEFLL
                     FNWSIIPY"
BASE COUNT          464 a          143 c          133 g          402 t
ORIGIN      
        1 ttatttctta gaaattaaaa tgaattaagt aaatggagga attgatatga taataattag
       61 aagtcaagat aaaactaatt taatgcagat aaaccaaatt aaaatagatg gtagtcaagt
      121 ttatgcagta tttgaaagta aaattgatac tgtaaaaata ggagattatg aaaataatac
      181 aagagctata caagtgttgg acaatataca aaacttcatt gaaaatggaa caaaatatga
      241 ttatataaca tcaaataaag tcagatacaa tgttaataaa atatttcaga tgccagctaa
      301 atagtgagtg tgcattttag tttaataact aaagcccact ttcttttgta gtatgaaaga
      361 gggctttaca tatttgtaaa tatcgaagta cacttgtttt atcaataaat tatttaataa
      421 ggtataatgg accaattaaa caataaaaat tctcctaaaa cagcaagtat taaatatata
      481 atagcttcat ttttgtaaag agaggtaatt tttttgctta tgtcatcatc aattgtaata
      541 gcaatttcat cttgaataat atttttatat atagatggga aaatatcttt tttctttata
      601 agattaaata aattatttac acctacccat ataaaatatc ctaaaacagc acctaatgtg
      661 ttcatcatta aatcatcaat atctgtagct cttaagttaa acaattgaca aagttcaatt
      721 gctaatgaaa aacctaatcc agttaatgaa acattgataa tatttctaaa atttttccaa
      781 attaaaggta gtaaaaatcc taaaggcata aacataatta tatttaaaat atatgttaag
      841 atgccaactg agtcaaaagg tattagattt atttcatcaa ttctaaaaag cccactatac
      901 cttcctatat cccatatgct accaattcca gctttactaa gtgctagata gatatataat
      961 aaaaaaatat atacccatac taaatgtatc attacattct tttcaacttt caaatttttt
     1021 cgttttataa cgactatttg gtatattaag catggtaata taacgcaaat aaatgaataa
     1081 aatgtccata tcattttatt ttgtcccctt tcaaatttat gtttttagtt ttataagtac
     1141 ta
//
LOCUS       DAMJYN010000235         1032 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.242, whole genome shotgun sequence.
ACCESSION   DAMJYN010000235 DAMJYN010000000
VERSION     DAMJYN010000235.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1032)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1032)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1032
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.242"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            165..305
                     /locus_tag="PC466_003808"
     CDS             165..305
                     /locus_tag="PC466_003808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2771117.1"
                     /translation="MEKSNTTVTKKEKIEDIGMKLEHLLSEDITFYELLLEILYKEKE
                     EN"
     gene            complement(302..673)
                     /locus_tag="PC466_003809"
     CDS             complement(302..673)
                     /locus_tag="PC466_003809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2771118.1"
                     /translation="MESLGDRIANLRKELDINQKELATKVGITEASLSRYENNLREPK
                     SEIIVRLAKALETSTDYLLGVNDNTKISKEDKLIIENLSVSEKTKKLLEKIYSLEKED
                     REAIEKMIDNAYLKRFLKEEN"
BASE COUNT          395 a          106 c          128 g          403 t
ORIGIN      
        1 agaataaaag tattattata taattaagat aattatctag ggaaattttg gataatcaaa
       61 atatatttta taaaatcaaa atacaattac ataaacttta ttaaaaattt gttgggaatt
      121 tctgactagc attaagaacg taagtttgtt gggggatggt atatgtggaa aagtcaaaca
      181 ctactgttac aaaaaaagaa aaaattgaag atataggaat gaaattagaa catttattga
      241 gtgaagatat tactttttat gaattattac ttgagatttt gtataaagaa aaagaagaga
      301 attaattctc ttctttaagg aatcttttta aataggcatt atcaatcatt ttttctatag
      361 cttctctatc ttctttttca agagaatata ttttttctaa gagctttttt gttttttcac
      421 ttactgataa gttctctatg attaatttat cttctttgct tatttttgta ttatcattta
      481 cgcctaataa ataatctgtt gatgtttcta atgcttttgc taatctaact attatttcac
      541 ttttaggttc tcttaaatta ttttcataac gtgacaagct agcctcagtt ataccgactt
      601 tagtagcaag ttctttttga tttatatcta attcttttcg tagatttgct attctatctc
      661 ctaaactttc catatgtaca tcactcctta ccgaaattat aagttatttt gataaaaagt
      721 aaaataaaat taccaaaaat ataaaaaaaa agggttaaaa taataaaata tattgaaaat
      781 taccatttgt atatgtataa tatgaattat acaaatggta atttgatgag aggtggtatg
      841 ttgaaataag aaactgaatt aattaataaa tatatagaaa gttttgaaaa cccttaattg
      901 agatataaac aatatgtaca aaattttttg caagtaaaat taccaaatgt ataaaataaa
      961 tcagtagcat agataatttt atgctttaat acattagatt atttaattta gttataatgg
     1021 tcaaaaatgc aa
//
LOCUS       DAMJYN010000236         1024 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.243, whole genome shotgun sequence.
ACCESSION   DAMJYN010000236 DAMJYN010000000
VERSION     DAMJYN010000236.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1024)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1024)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1024
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.243"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            300..767
                     /locus_tag="PC466_003810"
     CDS             300..767
                     /locus_tag="PC466_003810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDF2771119.1"
                     /translation="MKFLNVLIVVEDIEKSKKFYYDILGLKVICDFGENVVLEGNISL
                     QEKKLWLEFINKSDSEVKFNGNDAELYFEEDNFDTFVERLSTMKGIDYVHLAIEHRWG
                     QRAIRFYDLDGHIIEIGETMSSVCRRFLDSGLSIDEVAKRMDVTVEYIESVLE"
BASE COUNT          393 a           70 c          168 g          393 t
ORIGIN      
        1 tattagtgta tattaatatt cccttgaaat taaaaaaaca tagatatttc agtaatctaa
       61 aatagtctac aaaaataaca gttttagcaa aattaataag aatacatata gatttaaacc
      121 taaaagtatg aacatgtctg ttttttacaa gattaaaatt tatattatat gataaaatta
      181 acttaactat ttcaataaga cttataattt ttttctttat actagacctt attgaaacct
      241 ttatagttta attctaatta tatattataa ataaagtatg tgtatattaa ggaggtaata
      301 tgaagttttt aaatgtttta atagtagttg aagatattga gaaatcaaaa aagttttatt
      361 atgatatttt ggggttaaag gtaatctgtg attttggaga aaatgttgta ttagaaggta
      421 atatatcatt acaagaaaaa aagctttggt tagaatttat taataagagt gacagtgaag
      481 ttaagttcaa tggaaatgat gctgagttat attttgagga agataatttt gatacttttg
      541 ttgaaagatt gagtacaatg aaaggtatag attatgttca tctagctata gagcataggt
      601 ggggtcaaag agcaattaga ttttatgatt tagatgggca tattattgag attggagaaa
      661 ctatgtcatc tgtgtgtaga cgttttttag atagtggtct ttcaatagat gaggtagcta
      721 aaagaatgga tgtaactgtc gaatatattg aatcagtttt agaatagatg gattatatta
      781 aagtaaaact atattttgta tagaagtaag ggctgtaagt aaacttgtat ggaaacaaat
      841 ttacttacag tttttgtttt tgtaagatac agaatataat atttgttata attttatttg
      901 gatttttaaa aagtgcatga ttttccttac atattataat agaatttaat atttattgga
      961 tgatttaaat ttagaaaaat ataagtatta gcttataaaa gataattata cttactatca
     1021 agct
//
LOCUS       DAMJYN010000237          952 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.244, whole genome shotgun sequence.
ACCESSION   DAMJYN010000237 DAMJYN010000000
VERSION     DAMJYN010000237.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 952)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 952)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..952
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.244"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            20..880
                     /locus_tag="PC466_003811"
     CDS             20..880
                     /locus_tag="PC466_003811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HDF2771120.1"
                     /translation="MLLKKDRITFSEILILIVGCILMAISLNLFFNPHAIAAGGITGL
                     GVVLNSLFGVELWIVNLLLNVPLFIFAYKILSKKDCFKTVLGIIFLTIALKLTANMAT
                     LDITNDMYLAIISGSILMGVGQGLIFRINGSTGGTDLMALLLNKYFPTFSIPVLMGIV
                     DCVVVVLSGIVNRQVEIALYSTVALYILVKVSDLLIEGFNYSKSFTIISDLSKDISKK
                     IMEDLDRGATILKGEGAYTGENKNVLLVVVEKKEVVELKKLVKNVDPNAFIIITDIHE
                     ALGNGFKKIE"
BASE COUNT          343 a          106 c          149 g          354 t
ORIGIN      
        1 aatctatata taaggagtga tgttattgaa aaaagataga ataacttttt cagaaatttt
       61 aatattaatt gtaggctgta tattaatggc catttctctt aatttatttt ttaatccaca
      121 tgcaatcgct gctggtggta taacaggact tggagttgtt ttaaattcat tattcggtgt
      181 agaactttgg attgtcaatt tacttttaaa tgttccatta ttcatatttg cttacaaaat
      241 actttcaaaa aaagattgtt ttaaaacggt tttaggaata atttttctta ccatagcact
      301 taagcttact gcaaatatgg ctacattaga tataacaaat gatatgtatc ttgcaattat
      361 atctggttct attttaatgg gagttggtca aggacttatt tttagaataa atggctctac
      421 aggtggaact gatttaatgg cactcctact aaataaatat tttcctacat ttagtatacc
      481 tgttttaatg ggtattgtag actgcgttgt agttgtttta tcaggtatag taaatagaca
      541 ggttgaaatt gcactttatt caactgtggc tttatacatt ttagtaaaag ttagtgactt
      601 gcttattgaa ggatttaatt attccaaatc attcactatt atatctgacc tttcaaaaga
      661 tataagtaaa aaaataatgg aagatttaga tagaggtgca actattctaa aaggagaagg
      721 tgcatatact ggagaaaata aaaatgtact tttagtagta gttgaaaaga aagaagttgt
      781 cgaattaaaa aaattagtaa aaaatgtcga ccctaatgct tttattataa ttacagatat
      841 acatgaagct ttaggtaatg gatttaaaaa aatagaataa ctaacaataa atagcaagta
      901 taattaacat atacaaattc aactttttat atgttatatt atacttgcta tt
//
LOCUS       DAMJYN010000238          843 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.245, whole genome shotgun sequence.
ACCESSION   DAMJYN010000238 DAMJYN010000000
VERSION     DAMJYN010000238.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 843)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 843)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..843
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.245"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            215..721
                     /locus_tag="PC466_003812"
     CDS             215..721
                     /locus_tag="PC466_003812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase"
                     /protein_id="HDF2771121.1"
                     /translation="MGFREVKIEELQFNPFTKIGKEWLLITAGDSEKFNTMTASWGGV
                     GVYWGKNVVTTYIRPQRYTKEFVDSNDTFTVAFFDETYREALNICGTISGRDINKIEK
                     AGLTPYFVDDTVAFEEANMIIVCKKLYHGNMPPENFDAKENDKKWYPEKDYHTMYISE
                     IIKVLVKE"
BASE COUNT          345 a           82 c          134 g          282 t
ORIGIN      
        1 aaaaatatat tatatacttt ataatcaata tattttatct atattttaca cttataaaat
       61 atgaaaacta cttattgcga aagtaattga tttgttgtat tataatttac atgaattatg
      121 taggacaatc aaaagtcagt attataagag tacatatatt caaattttta acaattaatt
      181 tatataatta aaaaatgaag ggtaggatga agtcatgggt tttagagaag taaaaattga
      241 ggaactacag tttaatccat ttactaagat tggcaaagaa tggttactta taacagctgg
      301 tgattcagaa aagtttaaca caatgactgc tagctggggt ggtgttggag tctattgggg
      361 taaaaatgtt gttacaactt acataagacc acagagatat acaaaagaat ttgtagatag
      421 taatgataca tttacagttg ccttctttga tgaaacgtat agagaggctt taaatatttg
      481 tggtactatt tctggtagag atataaataa aatagaaaaa gcaggactta caccatattt
      541 tgtggatgat acggtagctt ttgaagaagc taatatgatt atagtatgta aaaagctata
      601 tcatggtaat atgccaccag aaaactttga tgctaaagaa aatgataaaa aatggtatcc
      661 agagaaagac tatcatacta tgtacatttc agaaattata aaagttcttg taaaagaata
      721 attataataa aaaatatatg aaaagaactt attataagta aatgactgtg ctttcttatc
      781 tgatatctaa gtagatgcta ctaactaaat aaatattaat tttaaataaa tactattata
      841 aaa
//
LOCUS       DAMJYN010000239          817 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.246, whole genome shotgun sequence.
ACCESSION   DAMJYN010000239 DAMJYN010000000
VERSION     DAMJYN010000239.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 817)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 817)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..817
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.246"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            68..766
                     /locus_tag="PC466_003813"
     CDS             68..766
                     /locus_tag="PC466_003813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF2771122.1"
                     /translation="MEKKYFEIHGVPSILWGNPSSKLYIYIHGQCGNKEEAEAFANIA
                     VPHEYQVLSVDLPEHGERKREKNSFNPWHVVPELVSIMEYAKCHWNQISLYANSIGAW
                     FSMLSFEKENLRECIFVSPILDMQQLISNMMLWANVSEEQLKHELIIPTSFGHTLSWE
                     YLQYVKQHPITQWNVPTKILYGKHDELTEIGVVEKFVEKFNCNLTILENGKHWFNTPQ
                     ELNSLYEWLNTLVK"
BASE COUNT          309 a          109 c          129 g          270 t
ORIGIN      
        1 tacaacatta ttttatagtt tgattaattc aacaatcact aatatatcaa actgaaagga
       61 gatttttatg gaaaaaaaat atttcgaaat tcatggagtt ccttcaatcc tttggggaaa
      121 tccttcaagt aaattatata tttacataca tggacaatgc ggcaataaag aggaggctga
      181 agcttttgct aatattgcag ttccacatga gtatcaagtt ttaagtgttg atttgcctga
      241 acatggagaa cgtaaaagag aaaaaaattc atttaaccca tggcatgttg ttccagaatt
      301 agtatctatt atggaatatg caaagtgcca ctggaatcaa atttcgttat atgcaaatag
      361 cattggagca tggtttagta tgttaagctt tgaaaaagag aacttaagag agtgtatttt
      421 tgtatctcca attctagata tgcaacagct catttcaaat atgatgcttt gggcaaatgt
      481 atcagaagaa cagcttaaac atgaactaat tatcccaact tcatttgggc atactctttc
      541 atgggaatat ctacaatatg taaaacaaca tcctatcact caatggaatg taccaacaaa
      601 aatattatat ggtaaacatg atgaacttac tgaaatcggt gttgtagaga aatttgtaga
      661 aaagtttaat tgcaacctta ctattctgga aaatggcaaa cattggttta acacaccaca
      721 agaattaaat tcattatatg aatggttaaa tactttagtt aaataaaaaa taattatatt
      781 attaatatga ttaaattatt tataaatgtt atttaat
//
LOCUS       DAMJYN010000240          807 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.247, whole genome shotgun sequence.
ACCESSION   DAMJYN010000240 DAMJYN010000000
VERSION     DAMJYN010000240.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 807)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 807)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..807
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.247"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            79..645
                     /locus_tag="PC466_003814"
     CDS             79..645
                     /locus_tag="PC466_003814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HDF2771123.1"
                     /translation="MRKLEEILEYNKSFVENKEYEQYVTSKHPNKKIVVLSCMDTRLT
                     ELLPKAMNLKNGDVKLIKNAGATIMHPFGSIMRSVLVAIYEFDVDEVMVVGHHGCGMC
                     NVDTDKLLGKILDRGISNDVILTLRSAGIDTKQWLHGFDSAEESVKDSIDLIKGHPLI
                     PDGIIVHGLIISPETGKLDVVVNGYEDK"
BASE COUNT          309 a           68 c          149 g          281 t
ORIGIN      
        1 attaaattat atgtgtatat attgtacttt aatagtgata taataataaa aaaattttta
       61 aagagggtga tattacatat gagaaaactt gaagagatat tagaatataa taaatcattt
      121 gtagagaaca aagaatatga acaatatgtg acatcaaaac atccaaataa aaaaatagta
      181 gtcttatctt gtatggatac aagattaact gagcttttgc ctaaggctat gaatttgaaa
      241 aatggagatg tgaaactaat aaaaaatgca ggagctacta taatgcatcc ttttggaagt
      301 attatgagaa gtgttttagt tgcaatttac gaatttgatg tagatgaggt tatggttgta
      361 gggcatcatg gatgtggtat gtgtaatgtt gatacagata agttacttgg taaaatttta
      421 gatagaggaa tatctaatga tgtaatactt acacttcgta gtgctggaat tgatacaaaa
      481 caatggttac atggattcga ttctgcagaa gaatctgtaa aagatagtat tgatttaata
      541 aaagggcatc ctttaattcc agatggtatt attgtacatg gtctaattat atcacctgaa
      601 actgggaagt tagacgttgt tgtaaatgga tatgaagata agtagagtat tgtaatgtta
      661 tataatcaag atactgttga atatgatgtt gtttcaaaat ttattttggg acaacttttt
      721 tatttgaaaa tatatgaaaa ggtttatttt aagctttaca ataaaaaata taagtagctg
      781 actaattaaa aatcttacta ttattta
//
LOCUS       DAMJYN010000241          752 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.248, whole genome shotgun sequence.
ACCESSION   DAMJYN010000241 DAMJYN010000000
VERSION     DAMJYN010000241.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 752)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 752)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..752
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.248"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            <1..>752
                     /gene="tuf"
                     /locus_tag="PC466_003815"
     CDS             <1..>752
                     /gene="tuf"
                     /locus_tag="PC466_003815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887863.1"
                     /note="EF-Tu; promotes GTP-dependent binding of
                     aminoacyl-tRNA to the A-site of ribosomes during protein
                     biosynthesis; when the tRNA anticodon matches the mRNA
                     codon, GTP hydrolysis results; the inactive EF-Tu-GDP
                     leaves the ribosome and release of GDP is promoted by
                     elongation factor Ts; many prokaryotes have two copies of
                     the gene encoding EF-Tu; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HDF2771124.1"
                     /translation="ELLELVEMEVRDLLTEYDFPGDDTPIVRGSALMALEDPKSEWGD
                     KIVELFEQIDEYIPAPERDTDKPFLMPVEDVFSITGRGTVATGRVERGVLKVQDEVEL
                     VGLTEAPRKVVVTGVEMFRKLLDQAQAGDNIGALLRGVQRNEIERGQVLAKTGSVKAH
                     TKFTAEVYVLKKEEGGRHTPFFDGYRPQFYFRTTDVTGACKLPEGIEMVMPGDNVTME
                     VDLINSIVVEEGLRFSIREGGRTVASGVVATI"
BASE COUNT          310 a           94 c          187 g          161 t
ORIGIN      
        1 gagttattag agttagtaga gatggaagta agagatttat taacagaata tgatttccca
       61 ggagatgaca ctccaatagt aagaggttca gcattaatgg cattagaaga tccaaagagc
      121 gagtggggag ataagatagt agaattattc gagcaaatag atgagtatat accagctcca
      181 gagagagata cagataagcc attcttaatg ccagtagagg atgtattctc aatcacagga
      241 agaggaacag ttgcaacagg aagagtggaa agaggagtac taaaagtaca agacgaagta
      301 gaattagtag gattaacaga agcaccaaga aaagtagtag taacaggagt agagatgttc
      361 agaaaattat tagaccaagc acaagcaggg gataatatag gagcattatt aagaggagta
      421 caaagaaacg agatagaaag aggacaagta ctagcaaaga ctggatcagt aaaggcacac
      481 acaaagttta cagcagaagt atatgtactt aaaaaagaag agggtggaag acatacacca
      541 ttctttgatg gatatagacc acaattctat ttcagaacaa cagacgtaac aggagcttgt
      601 aagttaccag aaggaataga gatggtaatg cctggagata acgtaacaat ggaagtagac
      661 ttaataaact caatagttgt agaagaggga ttaagattct caataagaga aggtggaaga
      721 acagtagctt caggagttgt tgctacaata at
//
LOCUS       DAMJYN010000242          751 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.249, whole genome shotgun sequence.
ACCESSION   DAMJYN010000242 DAMJYN010000000
VERSION     DAMJYN010000242.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 751)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 751)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..751
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.249"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
BASE COUNT          307 a           52 c           88 g          304 t
ORIGIN      
        1 aatttattga atttcaataa taaattgttg atataatata taaaaccatt ataatataca
       61 ctaaaaataa gaatgtataa ggtggtaaat ttatataaaa aagaatatga gttgtaaaat
      121 attaaataat attgtactaa ttggaataat tttaacttta ttatagatta ttttaatgcc
      181 attagtactg atggtgtatt ttaaaattgg tataagcatt acaaatacga atatgccaac
      241 tgtaatatgt aatataagta gctatataca tatgtgctgt cccatatatt gtatcattgt
      301 ttatattaaa aagattatgt aaattggtat caatcaataa atcattttca gaagaaatac
      361 ctaaaaactt aaaaaatacc tatatgtgta tttagttaga ttggagattt ttacatttaa
      421 ttttatagtg acaatattat attattgtta tgatgtctat ttatatgcaa ttactataat
      481 atcagaactt atagtatcat ttgtttcatt atcaataagg ttttttactt tgttttgtca
      541 attttattaa aaaaagttat tgatataaaa gataagaagg ataaaactat atgacagatt
      601 tcaaacataa gagtggatat ttatataata gatattttat agttaatttt attagatttt
      661 atttaatact gtaatattaa tatcacaata tattaataat gtattaaaga ttgaattttg
      721 tagataacta taatttattg agagtgataa a
//
LOCUS       DAMJYN010000243          737 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.250, whole genome shotgun sequence.
ACCESSION   DAMJYN010000243 DAMJYN010000000
VERSION     DAMJYN010000243.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 737)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 737)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..737
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.250"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            <1..625
                     /locus_tag="PC466_003816"
     CDS             <1..625
                     /locus_tag="PC466_003816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF11 domain-containing protein"
                     /protein_id="HDF2771125.1"
                     /translation="AGEIRNIIIRGIVSQTAIGTIINTATVSSTTPDPNLNNNTSTSE
                     IDISSSADISVIKLANKTEACVEEQIDFVIVVSNAGPENAQNVTLIDNVSDKLKKAVF
                     SLDRGVSFQPWTGSLNIGTLPAGTLRVILLRGIIKSTCLDRLTNIAEVTSTTPDSNLN
                     NNISRVQVEIKQCCCNDCCCNNCSNCCCNDCGCKDCCCNCCKNDFWC"
BASE COUNT          300 a           90 c          118 g          229 t
ORIGIN      
        1 tgctggagag ataagaaata tcataataag gggaatagta agtcaaacag caataggtac
       61 aattataaat acagcaacag taagttcaac tacacctgac ccaaatctaa ataacaatac
      121 ttcaacatca gaaatagata taagttcatc agcagatatt tctgtaataa aattagcaaa
      181 taaaacagaa gcatgtgtag aagagcaaat agattttgta atagtagtat caaatgcagg
      241 accagaaaat gctcaaaatg ttactttaat agacaatgtt tcagataagc ttaagaaagc
      301 agtattttca cttgatagag gtgtaagttt ccaaccatgg actggaagtc ttaatatagg
      361 tacactacca gctggaactt taagagttat tctattaaga ggaattataa aatcaacatg
      421 tcttgataga ttaacaaata ttgcagaagt tacttcaaca acaccagatt caaaccttaa
      481 caataatata tcaagagtgc aagtagaaat aaaacaatgt tgttgtaatg attgctgttg
      541 taacaactgt agtaattgtt gttgcaatga ttgtggttgt aaagattgtt gctgtaattg
      601 ttgtaaaaat gacttttggt gttgatttta taaaataatt ttgtatacct taaattaaac
      661 tgaaataaaa aataaattca catatgagta aaatatttta taaatattaa taaattttct
      721 atctttgata tggacca
//
LOCUS       DAMJYN010000244          735 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.251, whole genome shotgun sequence.
ACCESSION   DAMJYN010000244 DAMJYN010000000
VERSION     DAMJYN010000244.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 735)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 735)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..735
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.251"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     regulatory      <1..67
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            150..635
                     /locus_tag="PC466_003817"
     CDS             150..635
                     /locus_tag="PC466_003817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HDF2771126.1"
                     /translation="MISELMLKNFGKSSINFKTKIKLNLREKPDINSLKLKSIPEGKI
                     VKLKCVDGIWAEVESNYDKGWLLYKYLERLSNAKNNSNDTIKNRKKNYIGNIRTNGLS
                     LELRNDRTLESKVITTIPDGFKVEVCYSVGKWARVNINKNEKRYSGYVYNQYIEEHLS
                     L"
BASE COUNT          326 a           64 c          121 g          224 t
ORIGIN      
        1 ctaatgacgc aaaactatag ggactaaaat ctttatgtaa taaaggtcat gtcagccagt
       61 tgccaaaaag ataataattc tttttgttaa aagtattttt agagttatat attttaataa
      121 cttaatattt ggcaagagga gggcttaaga tgatatctga attaatgtta aaaaattttg
      181 gcaaatctag catcaatttt aaaactaaaa ttaaattgaa tttaagagaa aaaccagaca
      241 taaatagttt gaaattaaaa agtataccag aaggtaaaat tgttaagtta aaatgtgtag
      301 atggaatatg ggcagaagtt gagagtaatt atgacaaagg ctggttactt tataaatatt
      361 tagaaagatt aagtaatgct aaaaacaata gtaatgatac aataaaaaat agaaaaaaga
      421 attacatagg aaatataaga acaaatggat taagtttaga acttagaaat gatagaacat
      481 tagaatctaa agttataact acaatccctg atggttttaa agttgaagta tgttatagcg
      541 ttggaaaatg ggcaagagtt aatatcaata aaaatgaaaa acgatattct ggatatgtat
      601 ataatcaata catagaagag catttaagtt tataatacga tactagtgag ctttaaatat
      661 gttaataaat cacaaaaaag aatcccatta atgggattct tttttgtaga aacattataa
      721 cagaactaaa gagaa
//
LOCUS       DAMJYN010000245          723 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.252, whole genome shotgun sequence.
ACCESSION   DAMJYN010000245 DAMJYN010000000
VERSION     DAMJYN010000245.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 723)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 723)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..723
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.252"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            <1..>723
                     /locus_tag="PC466_003818"
     CDS             <1..>723
                     /locus_tag="PC466_003818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003467946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HDF2771127.1"
                     /translation="KNPVLIDKYLTGREIEVDAICDKEDILIPGIMEHLERAGVHSGD
                     STTMYPSQNISDEIKEKIVEYTKKIALDLNVLGMVNIQFIEFQNELYIIEVNPRASRT
                     VPYISKVSGVPIVDLATKCMLGAKLKDLGYGTGVYKEPKLVSVKVPVFSMSKLSKVEV
                     SLGPEMKSTGEVLGVGENLEEALYKGFLAAGRHMSDERGVVLATVNNHDKDEFIEIAK
                     DMKELGYTFVATEGTAKSLRENG"
BASE COUNT          292 a           75 c          154 g          202 t
ORIGIN      
        1 aaaaatccag tacttataga taaatatcta actggtagag aaatagaagt agatgctata
       61 tgtgataagg aagatatatt gatacctggt ataatggaac atttagaaag agctggagtt
      121 cactctggag atagtacaac aatgtatcca agtcaaaata tatctgatga aataaaagaa
      181 aagatagtag aatacactaa aaaaatagct ttagacctta atgtgcttgg tatggttaat
      241 atacaattta tagaatttca aaatgaatta tatataattg aggttaaccc tagagctagt
      301 agaacagttc catatataag taaagtaagt ggagtaccaa tagttgactt ggctactaag
      361 tgtatgttag gagctaaatt aaaggattta ggatatggta caggagttta caaagagcca
      421 aaattagtat cagtaaaagt accagtattc tcaatgtcta aattatctaa agttgaagta
      481 agtctaggac ctgaaatgaa gtctacagga gaagtcctag gtgtaggaga aaatttagaa
      541 gaagccttat ataaagggtt cttggcagca ggtagacata tgtctgatga aagaggagta
      601 gtacttgcta ctgtaaataa tcatgataaa gatgagttta tagagatagc aaaagatatg
      661 aaagaattag gatatacttt tgttgctaca gaaggaacag cgaagagttt aagagaaaat
      721 gga
//
LOCUS       DAMJYN010000246          700 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.253, whole genome shotgun sequence.
ACCESSION   DAMJYN010000246 DAMJYN010000000
VERSION     DAMJYN010000246.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 700)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 700)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..700
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.253"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            <1..423
                     /locus_tag="PC466_003819"
     CDS             <1..423
                     /locus_tag="PC466_003819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2771128.1"
                     /translation="TISKKYKMRSVNPLKAWVKEYNLHKEIKETPKGGLFMETRKTTL
                     DERVEIVKDCIEHDFNYNLIAKKYFVSYSQVRRWTLKYKENGIVGLEDRRGKAKKEDE
                     LTQLDEIKLELKIVKAEKHKLQLENAFLKKLKNIERGW"
     gene            417..>700
                     /locus_tag="PC466_003820"
     CDS             417..>700
                     /locus_tag="PC466_003820"
                     /inference="COORDINATES: protein motif:HMM:NF024673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDF2771129.1"
                     /translation="MVITLSKNENKYKAIQSLFNEKKASLMQLCEIAKVNRSGYYKWL
                     NRDKSNLELENIKLATLITNIYEEKKGVFCSLRMTLQLNREYKLNVNHKRV"
BASE COUNT          307 a           78 c          126 g          189 t
ORIGIN      
        1 actatctcaa aaaaatataa aatgaggtct gttaatccac taaaagcttg ggttaaggag
       61 tataatcttc ataaggagat aaaagaaacc ccgaagggag gactctttat ggagactaga
      121 aaaacaacat tagatgaaag ggttgaaatt gttaaagatt gtattgagca tgattttaat
      181 tacaatttaa tagcaaaaaa atactttgtt tcatacagcc aagttagaag atggactctt
      241 aaatataaag aaaatggtat agttggttta gaagaccgaa gaggtaaagc aaaaaaagaa
      301 gatgagttaa ctcaattaga tgaaataaag ttggaattga aaattgtaaa agcagaaaaa
      361 cacaaattac aactggagaa tgcattctta aaaaagttaa aaaacataga aagagggtgg
      421 taattacact atccaagaat gaaaataaat ataaagctat tcaatcctta ttcaatgaaa
      481 aaaaagcttc gcttatgcaa ttatgtgaaa tcgctaaagt aaatcgttct ggatactata
      541 aatggctcaa tcgagataaa agtaatttag aacttgaaaa cattaaatta gcaactttga
      601 taactaatat atatgaagaa aagaagggag ttttttgctc tttaaggatg accttgcagt
      661 taaacagaga gtataaactt aatgtcaatc acaagagagt
//
LOCUS       DAMJYN010000247          651 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.254, whole genome shotgun sequence.
ACCESSION   DAMJYN010000247 DAMJYN010000000
VERSION     DAMJYN010000247.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 651)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 651)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..651
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.254"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
BASE COUNT          245 a          114 c          101 g          191 t
ORIGIN      
        1 tgtaattatc aacttaagga ggtgaacaca gtgaaccgtt tagagcaaaa agaaaaagag
       61 gcgaacatac gtgaagccca tagcaaaacc tttagaaatt acgctatcgg actttcggtc
      121 atcgcctcaa cagtcaaact attaattagc tatcttactt aggtaagtcg gggacatcgt
      181 cccccttacc tcatattata aaacgaggtg ataaaaatga caaaatcaaa aatcaaaaca
      241 gttattaatt acgctttagg tgtattagtt atcttaattg ctctattcat tatcttttat
      301 ttataacagg ctcaataaac aaacggttca tttactatac aatgattatt caaacaatag
      361 aacgcttatt atcaagtgac ttatctgcat actatatcag tcaacaaaca ggcgtttccg
      421 cttctagtat acaaagactg agaagcggaa accgtaagat aaataaactc acaatagaca
      481 ctgcggaaaa actttatatg tatcaacttc agttagataa acaaagtcat ctagataaca
      541 ataaatagcc ttagggcgac cttatcataa atgtttatat catttacctt gtatatatgt
      601 ttaatcctcc ttagttgatg attaacgtaa ataggagatg agagaatgaa a
//
LOCUS       DAMJYN010000248          618 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.256, whole genome shotgun sequence.
ACCESSION   DAMJYN010000248 DAMJYN010000000
VERSION     DAMJYN010000248.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 618)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 618)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..618
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.256"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            6..>618
                     /locus_tag="PC466_003821"
     CDS             6..>618
                     /locus_tag="PC466_003821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HDF2771130.1"
                     /translation="MLDAFITIVSSIIEIWSCKKVFDYTSQSKTDLKKLNMYFLFSVF
                     LIISSLYINIGANSRILICIFVMFVFYKSNYKVNIYKCLVISFFYWLILIGINGLSML
                     LVATVSNLDNMNVLLSGSLYRYEAIFLGKIMLGILLYVYKASFKNFKISKKEIYICIP
                     MIANLLSFFVLYDYIINLVKISPERRTAFLVIVLLLILSNISIF"
BASE COUNT          213 a           55 c           82 g          268 t
ORIGIN      
        1 ttattatgtt agatgcattt ataacaattg tttcttctat tatagaaata tggtcatgta
       61 aaaaagtttt tgattatact agtcagtcaa agaccgactt aaaaaaacta aatatgtatt
      121 ttctcttttc tgtttttctt attatttctt ctttatatat aaatatagga gctaatagta
      181 gaatcttgat atgtatattt gtaatgttcg ttttctataa gtctaactat aaggttaata
      241 tatataaatg tctggtaatc tcattttttt attggttaat attaataggt ataaatggat
      301 taagtatgtt attagtagca acagtaagca atttggataa tatgaatgtt ttacttagtg
      361 gcagtttata tagatatgaa gcaatattct tgggaaagat aatgttaggt atattacttt
      421 atgtttataa ggcttctttt aaaaatttta aaataagtaa aaaagagata tacatatgta
      481 ttcctatgat agcaaattta ttgtcatttt ttgtacttta tgattatatt attaatcttg
      541 taaaaatctc tcctgaaaga agaactgctt ttttagtaat agttttacta ttaatattat
      601 ctaacatttc aatctttg
//
LOCUS       DAMJYN010000249          587 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.257, whole genome shotgun sequence.
ACCESSION   DAMJYN010000249 DAMJYN010000000
VERSION     DAMJYN010000249.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 587)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 587)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..587
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.257"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(81..560)
                     /locus_tag="PC466_003822"
     CDS             complement(81..560)
                     /locus_tag="PC466_003822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HDF2771131.1"
                     /translation="MPNKLIKNLLSGILQILFFLLGLVIVVGGFKSFMYLCFSGEATL
                     QGTISGILMFILGVSYFIIIKSLIEVLSSSEHSLFVKDNVKRFRIIGYLLLLNSIMEF
                     ISTFGTTGKGMRFLDLGFGFYFTVPVFVYFITSLMSFVIADGFVKAIKIKEDNDLTI"
BASE COUNT          233 a          102 c           46 g          206 t
ORIGIN      
        1 accctaatat attttatttt aaattactag ttaatcactc ttttctggtt atttatctcc
       61 tatatattaa agtgtcacac ctaaatagtt aaatcattat cctcttttat ctttattgcc
      121 tttacaaatc catctgcaat tacaaaactc ataagagaag ttataaaata tacaaatact
      181 ggaacagtaa aataaaatcc aaatcctaaa tctaggaatc tcattccttt tccagtagta
      241 ccaaaagttg aaataaactc cattatagag tttaaaagca aaagatatcc aataatccta
      301 aatcttttta cattatcttt tacaaataag ctatgttcag aactacttaa tacttctatc
      361 aatgatttta taatgataaa atatgataca cctaaaataa acattaatat tccagaaata
      421 gtgccttgta gagttgcttc tccactaaaa cagaggtaca taaaactttt aaatcctccc
      481 acaacaatta ctaaccctaa aagaaaaaat aaaatttgta atataccact tagtaaattt
      541 tttataagtt tattaggcat cataccaact cctttaaaat attttat
//
LOCUS       DAMJYN010000250          514 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.258, whole genome shotgun sequence.
ACCESSION   DAMJYN010000250 DAMJYN010000000
VERSION     DAMJYN010000250.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 514)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 514)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..514
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.258"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            235..>514
                     /locus_tag="PC466_003823"
     CDS             235..>514
                     /locus_tag="PC466_003823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDF2771132.1"
                     /translation="MNLQSKWVNFLKPTYVSDEIKRKKLQVIIFFSITYGLSYSLGLL
                     AICFNHLIDSEILAQFMMILPLSSVSIAKFYTEGRNNDKYNFYSSVILF"
BASE COUNT          207 a           44 c           65 g          198 t
ORIGIN      
        1 ctgattgcat aaaaatgatt tttatataaa ttttaaacag aagaataaat ttctaacgaa
       61 attggatatt tcttctgtaa atacatattc aaaaaaagaa ttataagagt ttagtcagca
      121 gtcgtgtaag taataaggac tttataaata tatagaaata taatgatatg agtataagta
      181 gaaaaatttt atgattttta caattatttt ttataaaaag ggaggttatg tttgttgaat
      241 ttacaatcaa aatgggtaaa ctttttaaag ccaacatatg tcagtgatga aataaaaaga
      301 aaaaaactac aagttataat atttttttct ataacttatg gtttatctta ttcactaggt
      361 ttattagcaa tatgttttaa tcatttaata gattcagaaa ttttagctca atttatgatg
      421 atattgccat tatcttcagt ttctattgca aaattttaca cagaaggaag aaataatgat
      481 aaatataatt tctattcatc agtaatatta tttt
//
LOCUS       DAMJYN010000251          500 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.259, whole genome shotgun sequence.
ACCESSION   DAMJYN010000251 DAMJYN010000000
VERSION     DAMJYN010000251.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 500)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 500)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..500
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.259"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            <1..363
                     /locus_tag="PC466_003824"
     CDS             <1..363
                     /locus_tag="PC466_003824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2771133.1"
                     /translation="LMISNGLIALSGSLMAQFLGFSDVNMGIGTLVLGIASIIIGITL
                     FKKFTFIKDTTAIIVGSFIYQFTIYFAMSLGMLSTDLKLITAIVIIAFLATGNLNISL
                     KKTNAKLVPKINQKKEVL"
     gene            364..>500
                     /locus_tag="PC466_003825"
     CDS             364..>500
                     /locus_tag="PC466_003825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2771134.1"
                     /translation="MLQIKNLSKSFPNPYGEPNTIFENLSIDIEDGEFVSIIGSNGTG
                     KS"
BASE COUNT          178 a           71 c           77 g          174 t
ORIGIN      
        1 cttatgattt caaacggact tatagcttta tctggtagtc ttatggctca gttcttggga
       61 ttctcagatg taaatatggg tataggaact ttagttcttg gaattgcctc tatcataatt
      121 ggtattacac tatttaagaa atttactttt atcaaagata ctactgcaat aattgttggc
      181 tcttttatat accaattcac tatatacttt gcaatgagtt taggaatgtt atcaactgac
      241 ttaaaactaa taactgccat agttataata gctttcctag ctactggtaa cttaaatatt
      301 tcactaaaaa aaacaaatgc aaagctagta ccaaaaataa atcagaaaaa agaggtgttg
      361 tagatgttac aaattaaaaa tctttcaaag agtttcccta atccatatgg tgaacctaat
      421 actatctttg aaaatttatc aatcgatata gaagatggtg aatttgtaag tatcataggt
      481 agtaatggaa ctggtaaatc
//
LOCUS       DAMJYN010000252          481 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.260, whole genome shotgun sequence.
ACCESSION   DAMJYN010000252 DAMJYN010000000
VERSION     DAMJYN010000252.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 481)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.260"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(88..381)
                     /locus_tag="PC466_003826"
     CDS             complement(88..381)
                     /locus_tag="PC466_003826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2771135.1"
                     /translation="MISMIMMLIGVLFIVFGIILTAVEIKGKMPGFYGVGQNAVRKNA
                     IGIIAAGIALIFFRNGLDSIDSILTYGVFLVIELVVIGLYFLIRIKYDKDGNL"
BASE COUNT          188 a           83 c           24 g          186 t
ORIGIN      
        1 aattgtagat aaaactattt tataaaattt atctacaatt tttttatata aacatatatc
       61 aaaatcaaaa tattattaat ttatacttta aagattccca tctttatcat attttattct
      121 tataagaaaa tataatccta ttactactaa ctctatcact aaaaatactc cataggtaag
      181 aattgaatca atactatcta acccatttct aaaaaaaatt aatgctatac ctgctgctat
      241 aatccctata gcattttttc ttactgcatt ttgcccaact ccataaaaac ctggcatttt
      301 tccttttatt tcgacagcag ttaaaattat cccaaacact ataaataata ctccaataag
      361 catcataatc atactaatca tctaattacc tccttcactt aaggaaattt caatttctaa
      421 aatctaaaat aaataatatt tattttttat aataatattg tatatccaat taactatttt
      481 g
//
LOCUS       DAMJYN010000253          463 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.261, whole genome shotgun sequence.
ACCESSION   DAMJYN010000253 DAMJYN010000000
VERSION     DAMJYN010000253.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 463)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.261"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(<1..433)
                     /locus_tag="PC466_003827"
     CDS             complement(<1..433)
                     /locus_tag="PC466_003827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SufBD protein"
                     /protein_id="HDF2771136.1"
                     /translation="MKNLNLLINKLYSKNHNEAYKTFLFLENESLKSNITYCFFDSFL
                     EMIDNENSYIRTRGLLLISANAQWDIDNKIEINIDSILSHIVDKKPSVSRMFIKSIPN
                     ITKYKENLINRIKMELSNADISIYNNNMKPLVEKDINDTLSN"
BASE COUNT          155 a           59 c           45 g          204 t
ORIGIN      
        1 tattagataa tgtatcgttt atatcctttt ctactaatgg tttcatatta ttattataaa
       61 tacttatatc tgcattactt aattccattt ttatgcgatt aataagattt tctttatact
      121 ttgtaatatt aggtatggat ttaataaaca ttcttgatac agaaggtttt ttatctacga
      181 tatgacttag tatactatct atatttattt caattttatt atcaatatcc cactgagcat
      241 ttgcagagat taataacaat ccccttgttc gaatatatga gttttcgtta tcaatcattt
      301 ctaggaatga gtcaaaaaaa caatatgtaa tatttgattt taaactttca ttttctaaga
      361 ataaaaaagt tttatatgct tcattatgat tttttgaata taatttatta ataagtaaat
      421 tgagattctt caatcttctc atctccctca ttacaaatat tta
//
LOCUS       DAMJYN010000254          460 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.262, whole genome shotgun sequence.
ACCESSION   DAMJYN010000254 DAMJYN010000000
VERSION     DAMJYN010000254.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 460)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.262"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
BASE COUNT          200 a           46 c           55 g          159 t
ORIGIN      
        1 agacagtttt acatatttca actgtctcct aagaggggta tagttcacaa ctaagagtgg
       61 ctgggaactt aatataaagt tccagaaaag taaatcttca aaataattta ttgaaggaaa
      121 catcactcaa agttaagtaa aatatgtttc cttgctttta ttatatcaca aattaaaaat
      181 attaacacaa aattttgtga atatatactt attattgttc taaaaaaata tgtaaataat
      241 tgatttgatt tcatagaatt attgttgtaa tatttagtta aatatacaca atctcaatta
      301 aagaagataa gtattataaa ttcatatcaa aaaaatacat aaacttttaa gttataattt
      361 tataaaaagt cttttagtat cattatttca agaggaatta acatatgaaa aaataacttc
      421 attagaaaag tggataaaaa actggtaaga agatgactaa
//
LOCUS       DAMJYN010000255          443 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.263, whole genome shotgun sequence.
ACCESSION   DAMJYN010000255 DAMJYN010000000
VERSION     DAMJYN010000255.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 443)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.263"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
BASE COUNT          193 a           34 c           39 g          177 t
ORIGIN      
        1 ttttaagtat atttaaaatt ttatttatat atctttcatt atggttatat acaatatttg
       61 aattgtcatt aaatatgcca atagttttat atattattga ttttattaaa aaaagagata
      121 tacaaactaa taagttgtaa tctctcaaat ataaaaaaac aataaattaa ctcattggat
      181 tttttagtcc ataatataat tatagattat tcaacaaaca atctatagaa attgtggtat
      241 taatgtttaa ataaccaact ttttctaaaa taacctttat aggaatatat gagttcataa
      301 gtaaagatag cgaaataaga aaccagtttg gtatgtaaaa tctagatttt taattaaatt
      361 atcaagatta tatattatag tatcaaaaat agaaaattaa aattaaattt tttataataa
      421 attgtataca ttataaatta tat
//
LOCUS       DAMJYN010000256          420 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.264, whole genome shotgun sequence.
ACCESSION   DAMJYN010000256 DAMJYN010000000
VERSION     DAMJYN010000256.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 420)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.264"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            <1..>420
                     /locus_tag="PC466_003828"
     rRNA            <1..>420
                     /locus_tag="PC466_003828"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          106 a           97 c          130 g           87 t
ORIGIN      
        1 cgcctcccaa aaggtaacgg aggcgctcaa aggttctctc agtacggtcg gaaatcgtac
       61 gtagagtgta aaggcaaaag agagcttgat tgcaagacat acaggtcgag caaggatgaa
      121 aatcggactt agtgatccgg tggttctgcg tggaagggcc atcgctcaac ggataaaagc
      181 taccctgggg ataacaggct tatctccccc aagagtccac atcgacgggg aggtttggca
      241 cctcgatgtc ggctcatcac atcctggggc tgtagtaggt cccaagggtt gggctgttcg
      301 cccattaaag tggtacgcga gctgggttca gaacgtcgtg agacagttcg gtccctatcc
      361 gtcgcaggcg taggaaattt gagaagacct gtccttagta cgagaggacc gggatggacg
//
LOCUS       DAMJYN010000257          373 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.265, whole genome shotgun sequence.
ACCESSION   DAMJYN010000257 DAMJYN010000000
VERSION     DAMJYN010000257.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 373)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 373)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..373
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.265"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            177..293
                     /gene="rrf"
                     /locus_tag="PC466_003829"
     rRNA            177..293
                     /gene="rrf"
                     /locus_tag="PC466_003829"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            300..371
                     /locus_tag="PC466_003830"
     tRNA            300..371
                     /locus_tag="PC466_003830"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:332..334,aa:Asn,seq:gtt)
BASE COUNT          118 a           61 c           80 g          114 t
ORIGIN      
        1 tttgatgtta ttcattaaga tatatgtgca gtttttagag tgttaactct atgtaaagta
       61 ctaacttcaa ttgatgaagt atatatcgta aaaacaatta ctatttagta cttcaaaact
      121 attgacattt aaaaataaag atgttaatat aatacttgtc ttataaatag gcaatatgtg
      181 gttataatag caaagaggat acacctgttc ccattccgaa cacagaagtt aagctcttta
      241 gcgctgatgg tacttggtgg gaaactgcct gggagagtag gacgtagcca cgtgaatatt
      301 ccaaggtagc tcaatggtgg agcaaccggc tgttaaccgg taggctgtgg gttcgagccc
      361 cacccttgga gcc
//
LOCUS       DAMJYN010000258          306 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.266, whole genome shotgun sequence.
ACCESSION   DAMJYN010000258 DAMJYN010000000
VERSION     DAMJYN010000258.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 306)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 306)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..306
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.266"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(<1..291)
                     /locus_tag="PC466_003831"
     CDS             complement(<1..291)
                     /locus_tag="PC466_003831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2771137.1"
                     /translation="MSADGSYTMGASIVAFSLTNGISPVVATLMAILCGCTAGLVTGI
                     LHIKFKISNLLSGILVMGMLYSINLRIMGKSNIPLFSFKHLFNGEISPIVLAL"
BASE COUNT          123 a           52 c           49 g           82 t
ORIGIN      
        1 taaggctaaa actataggag atatttcccc attgaataag tgtttaaagc taaatagagg
       61 aatatttgat tttcccatta ttcttaaatt gatagagtat agcattccca taactaaaat
      121 accagaaagt aagttagata tcttaaactt aatgtgaaga atccctgtaa caagaccagc
      181 agtacaacca cataagatag ccattaaagt tgctactaca ggagaaatac cattagtaag
      241 agaaaatgct acaatagaag cacccattgt atagctacca tcagcagaca tgtctggaaa
      301 atctag
//
LOCUS       DAMJYN010000259          292 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.267, whole genome shotgun sequence.
ACCESSION   DAMJYN010000259 DAMJYN010000000
VERSION     DAMJYN010000259.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 292)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 292)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..292
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.267"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
BASE COUNT          128 a           13 c           42 g          109 t
ORIGIN      
        1 ttctttttat taatagaaat tgttgtataa aaataataaa agtgaggaga gtgatattta
       61 aataaaaaaa ttttaataag tattggtaat atagttttta gggatgatta ttttatgtaa
      121 aaagttgtta tttgtaaaga taaatataga aaatattata agtattgatt tagtgataat
      181 ctaaaaggtg agaattgtaa taaaaagaga acatatcctt caaatggatg taaacttata
      241 aataacatta ttacaagaga tttattatac atatactgca actattaatt ag
//
LOCUS       DAMJYN010000260          267 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.denovo.268, whole genome shotgun sequence.
ACCESSION   DAMJYN010000260 DAMJYN010000000
VERSION     DAMJYN010000260.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 267)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 267)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..267
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.denovo.268"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
BASE COUNT          113 a           20 c           29 g          105 t
ORIGIN      
        1 attcatgaca gtcaatatta ttgaaaagta acttataaaa ttatatataa ataataaaat
       61 taattttact atatacccat atatttagtt atattgcagg cagaatgtgg tttaccataa
      121 gcaaaaggac aataaaaaat atttttctat atttttatta tctttttgta aaagatttat
      181 tatttattgc attaaattaa taggcagtag aggcatagtt gataaaatta atgaagaaat
      241 taaacttatg aatataaatt tattatt
//
LOCUS       DAMJYN010000261        43834 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.guided.030, whole genome shotgun sequence.
ACCESSION   DAMJYN010000261 DAMJYN010000000
VERSION     DAMJYN010000261.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 43834)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43834)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43834
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.guided.030"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(127..429)
                     /locus_tag="PC466_003832"
     CDS             complement(127..429)
                     /locus_tag="PC466_003832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIBC"
                     /protein_id="HDF2771138.1"
                     /translation="MNKKIVAVCESERSLNSLKTAANDLGFDLVYEIQENDNIKNELS
                     IYDIEDASIVLFVTSDSIESIEKIDRFIDREFYEVDPKYIIEDAKSIVSEILIDLN"
     gene            complement(451..861)
                     /locus_tag="PC466_003833"
     CDS             complement(451..861)
                     /locus_tag="PC466_003833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HDF2771139.1"
                     /translation="MNKKKILVPIDGTERSMHSLEFIKGIFKKDEVEVEIMNVKELVF
                     IDGISLAEEIKNSENLGRRILDKAAEIMGEYDVKVHFTFGYPGDEIIRKAKEDNVDFI
                     VMTKSTKKGLTRMIGSVTASVVKQAKCIVMIVPE"
     gene            complement(1036..2964)
                     /locus_tag="PC466_003834"
     CDS             complement(1036..2964)
                     /locus_tag="PC466_003834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDF2771140.1"
                     /translation="MVWHIEYEIFSAIIVIFLMVYFFRSKFIPTLQNKIYCALLIFSF
                     LFILSNILGSFCLNNIDKIPIFITFLLNQIYLLLLPIPAALVSFYVMAIIYQDIRYMK
                     KRLLFLSIPLIICIILSITNPFTHILFGLSKETGYIRGCGYVATFASFFFYAIYSAFL
                     SFKYRKAMHESKIWAIRGFLIVSIVAIILQAIFLQYLLTGTACACSLLLTYLSMQNRG
                     LIIDDLTGVLNRQSFIQELDLNINTEQSGFIITIALDDFKFMNETFGTKNGDIALKEV
                     GKYLIQIHDVNHVYRIGGDIFSIVVNSQLGIEPDDIIRKIEERFKKPWLVEEISFNLA
                     TSIAVVYYPENAETTEDVIVAIDFSIHEAKRSESRRVVYADASISEKIKKKHVIKNCL
                     KEALKNDGFEVYYQPIFSNSRGRFTSAEALLRLEHKELGFIPPDEFIPIAEQTGLINS
                     IGLVVFEKVCRFIASDEFENLKLDNIAVNLSVVQCMQKNLADDLLYLMNKYNVSPTKF
                     KLEITETVAMGSFNIIKETMERLIDLGVKFALDDFGIAYSGVTNMLSLPFSVIKLDKS
                     LIWSMNEDSRHKLTVETIIALINKLNMKAVAEGVETIKCAEDLIAMECEYLQGYYFSK
                     PVPEDVFKNLLKENTFTS"
     gene            complement(3140..3628)
                     /locus_tag="PC466_003835"
     CDS             complement(3140..3628)
                     /locus_tag="PC466_003835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HDF2771141.1"
                     /translation="MKITVLYQTRSGNTERVAKLIEDGAKKVDGVDVKLMRLDNIDLD
                     YLNESKAVIFGTPTYLANTTWEVKKWFDEDSKKVNLAGKLGAVFATCDYICGGPDVAI
                     LTIVGHLMVKGMLVYSGGGSLGKPFIHLGHVHSIEGPELQDEKAIIFGERIATKAKEL
                     FA"
     gene            complement(3764..4774)
                     /locus_tag="PC466_003836"
     CDS             complement(3764..4774)
                     /locus_tag="PC466_003836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4116 domain-containing protein"
                     /protein_id="HDF2771142.1"
                     /translation="MHEDKNDIFESIDTEDFDNKTEEECLELVRKNGLNLIYIKNQTE
                     EICLEAVRQNCNAIKCVQNQTEKICIEAVKQDWRMLEFVEESTEEICMLAINQDGTAL
                     KYIENQTEELCLRAVEKNGAALEYVKEQTEEICIEAVRNSEFGLARVKNQTEKICMEA
                     VKHCSYNLKWVENQTEEICMEAVRQNGLDLKFVKNQTETICLRAVRQNGMALEFVKEQ
                     TVGICLKAVRQYGMALKFVKEQTEEICTEAIKQDKRALSFVKGDKEKYKALYDNNEPF
                     AKRYVRNVIEKENRALIKKGEENAKIKIAGKLYDRGMSFEDISDIVEIEISKLKVSLG
                     VF"
     gene            5262..5606
                     /locus_tag="PC466_003837"
     CDS             5262..5606
                     /locus_tag="PC466_003837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2771143.1"
                     /translation="MDQIKRLHELQQKSYLTKEEFEELKNNTYIERFELRDECDNSYI
                     YTFYTNDKCNDIKFIKSQFIVTLIKIGFLCECGGVFRQKKIVDEYDYGYNAIYKCDSC
                     GKELDKEVENYD"
     gene            complement(5938..7314)
                     /locus_tag="PC466_003838"
     CDS             complement(5938..7314)
                     /locus_tag="PC466_003838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent Fis family transcriptional
                     regulator"
                     /protein_id="HDF2771144.1"
                     /translation="MKEQWYKDIFARILSMTDDGFIVVNTSGVIIDINDKYCDFLGKE
                     RKDIIGQNIQSIIPNTKMLDVMKDKYCEEGAIHHYSGGNTKEKSVIVSRSYVENDNGE
                     VVAGVAQVKFRLQSFDVAKKLMSEYMELQYYKEQFKDNCGFDKLIGENRDFIELKKTG
                     VKASKTNFPVLLTGETGTGKEVFARAIHNNSSRSDKPMVSINCAAIPEELLESELFGY
                     DEGAFTGAKKGGKKGKFLVANNGTIFLDEIGDMPLTMQAKLLRVLQESEIEPVGGLKT
                     IKIDVRVISATRKNLSKMVEEGLFREDLYYRLNVINIHMMELKDRQDDILLLANYILN
                     KLNVEYKELKVLSDKVKNCFINYTWPGNIRELQNVIKSAYAVSDDMVIMMCDLPSKMD
                     NISRVAQCNVDSNCSIHEMVENYEKSLIIDVLRKYNWKCSKAAEVMGIHKSLLYKKIK
                     KYEIELNN"
     gene            complement(7413..8435)
                     /locus_tag="PC466_003839"
     CDS             complement(7413..8435)
                     /locus_tag="PC466_003839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HDF2771145.1"
                     /translation="MMRAKVNQGINLNDYNGVWVIGEQREGKINPVTIELIGEGRKLA
                     DQLGKELEVVIAGYEVEKEVKELLHYSVDKVYYINDPLLKDFTTDGYAISIANLIERK
                     KPEVVLVGATSIGRDIAPRIAGKVGTGLTADCTKLEIDSTDNKLLQTRPAFGGNLMAT
                     IVCPKNRPQMSTVRPGVMAKAVRNESETGILEVVTPELTEKMIRTRLVEVLPQEKKSV
                     NLTDARIIVSGGRGLKRAEGFELIKELADKLGAEIGASRAAVDSGWIEHSHQVGQTGT
                     TVRPELYIACGISGAIQHLAGMSDSKYIVAINKDAKAPIFSICDYGIVGDLYEIIPEM
                     IESLNR"
     gene            complement(8446..9240)
                     /locus_tag="PC466_003840"
     CDS             complement(8446..9240)
                     /locus_tag="PC466_003840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HDF2771146.1"
                     /translation="MNIVVCLKQVPDTNEVKINKETGTLIRDGVPSIINPDDRNALEE
                     ALKMKDELGAVIKVISMGPPQAKSALKEALAMGADEAYLISDRAFGGSDTWATSTIIA
                     AAIEKVGKYDVIFCGRQAIDGDTAQVGPEVAEFLGIPQVTYAKEVKVQDDKLLVTRYT
                     ETGDYLIEAKMPVLLTAIKELNNPRYPSVKGILEAYNNGDAKITVLTLADLDVDTTQI
                     GLKGSPTNVYKSFAPVKDKHNEIIEGINKKEKAEKLIEILFDLKLV"
     gene            complement(9251..10393)
                     /locus_tag="PC466_003841"
     CDS             complement(9251..10393)
                     /locus_tag="PC466_003841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="HDF2771147.1"
                     /translation="MDFRLTEAQLMLQRVAKEFAENEIAPIAAETDKTGIFPRELFSK
                     MAKIGFNGIGTPVEYSGSGGTDIEKVIVVTEIAKKCAASAAILSIHTIYAQAILKFGT
                     EEQKKKYLPMMAEGGCVGAFALTEPNAGSDAARAATTAIIDEETDEYVLNGTKCFISG
                     GGQAESLIIFALTDPSKGIKGMSAIIVDKGTPGFSIGKIEEKMGIHGSETAELIFDNC
                     RVPKSNLLGKEGKGFNIAMTCLDGARIGIGAQAVGIAEGALEESIKYSKERVQFGKPI
                     SALQGIQWYIADMATMVESAKLLVYYAADLKARGEKHTKEAAMAKYNASSTAREVTNL
                     ALQIHGGYGYMKDYPLERMYRDAKITEIYEGTSEIHKVVISRAVLG"
     gene            complement(10433..11665)
                     /locus_tag="PC466_003842"
     CDS             complement(10433..11665)
                     /locus_tag="PC466_003842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase"
                     /protein_id="HDF2771148.1"
                     /translation="MLNKPLEGVKVIDLTYFVAGPGTSKILADWGADVIKVEPSFGDP
                     GRKTGATMTMPIDDYNNPFYSTYNSNKRGLSINLKSETGIEIMDKLLSEANVFVSSYR
                     TGALKRLGLDYESLSKKHPHLIWGQINGFGDFGPAKDNAGFDTVAFWARSGAMLDIAE
                     KDTSPINPPIAFGDATTSCSLSGGICAALYQQAKTGKGQKVMASLFGQAIWNASSLLA
                     STQFSDEYPKTRKNAISPVINSYRCKDGKWIFLSILEHERYFEALCRLFGREDLIKEE
                     KFASSVESKKNATELINILDGEFAKFTQNEMVEKLTAADIAHEKIQHVNDVVTDEQAI
                     ANNYIYEHTSKNGNKTMLASTPVKFGNIEVNMTCDAPLIGEHSDEILRELGYSDSDIE
                     ALIESGIVTMNKEACEIC"
     gene            complement(11802..13142)
                     /locus_tag="PC466_003843"
     CDS             complement(11802..13142)
                     /locus_tag="PC466_003843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HDF2771149.1"
                     /translation="MNTGVIISLVGIIIALSLLVVMVMKGINIFIIAIVCSSLVAITG
                     SLNVYDALKVDYMTGFVGFLQANFFIFLTGTLMGKIMEITGGAKSIAKMIVRWIGKDK
                     ALLSIPIACGILAYGGVSVFVVSFAVFPIALEIFKEADLPRRFIPAALTFGCSTFAMV
                     APGAPQIQNIVPASTLGTDIMAGAVNGFISCAVMFIVGSTILYKMVSKEKANGGHFIA
                     HESDIFDEAEATNSKRENGPNGVIALIPLIVSILIINVKVNGKAIVPIEVGVFIGALL
                     VYLLLNKYQDNTKIVGHVGDACKTTVVAICNTCAVVAFGSVVKSAVGFDFIVNAMTNI
                     PGPPIAGAAVGTTVIAGICGSASGGLGIAAPLLGPVFLAKGVSAAALTRTMAISSAAL
                     DSLPHNGYIVTVTNGLCKETHKDAYMPIFWVTVLTPFIGTIVAVLLFTMFPGLP"
     gene            complement(13236..14030)
                     /locus_tag="PC466_003844"
     CDS             complement(13236..14030)
                     /locus_tag="PC466_003844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="HDF2771150.1"
                     /translation="MESVMENLNNLKVEVKDKVCVITINRPKALNALNSDTLRELSQV
                     IDVVSENEAILGVIITGEGKVFVAGADIRQMQNYKSEEGRKYAGYAQGIFDKIEALEK
                     TVIAAVNGYALGGGCELAMSCDIRIASEKAIFGQPEVNLGVIPCFGGTQRLSRLVGTG
                     IAKELIFTGRQVNAEEAKSIGLINKVVPSDLLLEESMKMMNQIVEKAPIAIRYAKVVI
                     NKGIDMDLKNALELEKDIAGLTFATRDKQEGMNAFIEKRKPVFENK"
     gene            complement(14659..15852)
                     /locus_tag="PC466_003845"
     CDS             complement(14659..15852)
                     /locus_tag="PC466_003845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase"
                     /protein_id="HDF2771151.1"
                     /translation="MKKGALSNIKVLDLTRVLAGPYCTMMLADFGADVIKIEMPRKGD
                     DTRGFGPFVNGESLYYANINRNKKGITLNLKSEEGKNIFLEMVKHADVVVENYRPGVM
                     EKLGLGYDELAKVNNQIIYGAVSGFGCYGPYSERPGYDIIAQAMGGLMSITGQEGGEP
                     TRVGNAMGDVLGGMNLTIGILTALNARKIIGKGQRVDVSLVDSVVSSLETGIQRYFDS
                     GQPELMGNRYASAYPYDSFKASDGSFVIGCGNDKLFEKLCKKVLFREDLLIDERFKTN
                     LKRCEHYKALKPEIEKWSVKHTIKEAVDLISEAGVPAAPIYNLDCVTTDEHIAKAREM
                     IVDISHPIIGNMKVNGNPVKLMTTKAKIDMPAPSLGESNEEIYNGWLGFDSDKIKDLK
                     ENGVI"
     gene            complement(15928..17190)
                     /locus_tag="PC466_003846"
     CDS             complement(15928..17190)
                     /locus_tag="PC466_003846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2771152.1"
                     /translation="MDIIALLLFLGVIIIAFVRKNNAGILALAIGVIAVRIFGMDDKE
                     LYGAISNSMFTTLVGITLLFAIVNSTGALKLVAEKIVAASGKRVWLIPIAVFIAGFVV
                     AGVGPGAIPALAIIPAMAVPVAITVGYNPVMLALIGECGLMAGRMTPITPEGQIITTV
                     AEGVGIENVMPTILACQTLSTIVFSIVLFIIFKGYKLKKPINVIDSKQIEKFNIKQII
                     SLISIVVMIAFIIIFDMNVGLAAFAVSAVLIFFNIADEGECIKSIPWSTIVMVLGVGA
                     MMTIVDAAGGIDLMSNALSSLMNSKTATPIMSISAGLMSMVSSALAVVYPTMMPMCVD
                     IAKAVGGVDPLALIAAVGVGGSLAGVSPLSTGGALILAAMGSSKKDFNKEEQNKVFVQ
                     LFIMSAVGLLVIAVVSILSFNAITHLMN"
     gene            complement(17328..18224)
                     /locus_tag="PC466_003847"
     CDS             complement(17328..18224)
                     /locus_tag="PC466_003847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA lyase"
                     /protein_id="HDF2771153.1"
                     /translation="MSKVNIFEVGPRDGFQNLKEFLETDKKLKIIDGLIASGIKQLEI
                     SSFVSPKAIPQMKDAKEVATYCVEKYPDVKLYALVPNLYGAKVAWECGIRDISYVISL
                     SETHNKKNINRTHEESIDELKKIMNTYPDMNICIGMATVFGCPFEGLPKIEDAIRFAK
                     RLWENGIREINLADTIGIADPKQVRETISALVEALPECRWQVHIHDTRNMGMVNTLVA
                     IESGITTVQSTLGGLGGCPFAPGASGNTATEDLVYMLERMGYDTGVDFVKLLELSKYQ
                     KSFVNGVYSGHHVNIKSDSCNC"
     gene            18490..19494
                     /locus_tag="PC466_003848"
     CDS             18490..19494
                     /locus_tag="PC466_003848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HDF2771154.1"
                     /translation="MATIKDIAKDCGLSSATVSYVLSGKGNERRIPLHTQELILNSAD
                     KLGYKRSTPIKHNNIKIAFYWQDEGFELASTNILQAINHIISLEHLNINIIIRPYKVG
                     HLCDDEYFFANNYYDGIVLTGINADDIEYLVKNKPKIPVVVVNREIPGFSSVSIDNEE
                     TGRIAALHAIQNGKNDIAVVFNPTSFTCMTLRGKSFLKTCKEHGIHLSDSIYYCSNKI
                     DSGYDIAQKMLAKNSLKKVIFCNHDVVALGMMNAFHESGIVIGEDIQIFAASNGPSRL
                     MARSIPPLTVIDLKMEETAERSLRMIIDTVTGRINGIQQQVIYPSIIYRQSSPAQNLL
                     "
     gene            complement(19662..20381)
                     /locus_tag="PC466_003849"
     CDS             complement(19662..20381)
                     /locus_tag="PC466_003849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDF2771155.1"
                     /translation="MGRIGNIINRKGKQDAQRAKIFTKHARAIAVAAKEGGADPEYNA
                     ALKTAIEKAKADNMPNDNIDRAIAKGAGAGAGEDYETIVYEGYGPGGVAVIVETLTDN
                     KNRTAGNVRYYFDKNGGNLGTSGCVSFMFDKKGQILVGLGDGVSEEELMDVALEAGAE
                     DFITEEDGYEIITTPEDFSSVRDELKAKGYEFISADVKMIPQTTTVLTEESHLKMMNK
                     LVDMLEEDDDVQDIYHNWEVE"
     gene            complement(20464..21219)
                     /gene="nadE"
                     /locus_tag="PC466_003850"
     CDS             complement(20464..21219)
                     /gene="nadE"
                     /locus_tag="PC466_003850"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+) synthase"
                     /protein_id="HDF2771156.1"
                     /translation="MSNIKIQIDKTVEWLINKVNEANAKGLIVGVSGGIDSAVVANLI
                     KKAFPENSMGVIMSIKSNPQDREDALKVIEGCDIEYLDLDLIEPQSAILDMVVGNLKD
                     KHLYRAEYLKMTDANLRARVRMSTIYTIANNLGYLVVGTDNAAEIHTGYFTKFGDGGV
                     DILPIANLTKGEVYEWAKELGVHEDLINKAPSAGLWEGQTDEDEMGTTYNMIDAVLEG
                     RLDEVPKRDQEIIERLHRLSEHKRKTPAQPPKF"
     gene            21398..21784
                     /locus_tag="PC466_003851"
     CDS             21398..21784
                     /locus_tag="PC466_003851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HDF2771157.1"
                     /translation="MKKTDDLKKKYFDFNLKNTIIGVFTGFINGVFGSGGGTLLVPIL
                     NDIVKVEEHKSHATALSIIIFLTTASSVLYVSKGTYDVNLTIKVAVGSILGGIIGAKL
                     LNKVTGKFLRISFGIIMIIAALRMVF"
     gene            21784..22161
                     /locus_tag="PC466_003852"
     CDS             21784..22161
                     /locus_tag="PC466_003852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HDF2771158.1"
                     /translation="MLFALIGFFAGIIGGMGMGGGTILIPALVLLAGIDTKIAQSVNL
                     LSSIPMTLIALAIHIKNKNVIFKLVIPIAVFGVLGAVFGSLLANYLSSDILKKIFGIF
                     LLLVGLFEVKKGFCAKSDKKPLN"
     gene            complement(22247..22891)
                     /locus_tag="PC466_003853"
     CDS             complement(22247..22891)
                     /locus_tag="PC466_003853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HDF2771159.1"
                     /translation="MSNYRTLHEFGTDEITIEKSVFIGYAKPIKSEEEALEFINEIKK
                     KHKDATHNVWAYTVGKNMNIQRYSDDGEPQGTAGIPTLEVIKKEDLRDVVVVVTRYFG
                     GTKLGAGGLVRAYTKGAKLGLEAGKIIYKVMYQEVKVKIDYTQLGKVQNELMNLGYFI
                     KDTVYEDNVEIVVYSRLEDVEKLSEKMIDITNGTGKIILGEEFYLSEQNGEILI"
     gene            complement(23197..23640)
                     /locus_tag="PC466_003854"
     CDS             complement(23197..23640)
                     /locus_tag="PC466_003854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HDF2771160.1"
                     /translation="MIVRRCAGGVVFYANKVLIVKNDRGEWTLPKGKILGGGLPYESA
                     VQRVKVETGIDAKMIDVAGDTMYEFFSRSRQQEVCNAIMWYVMEACNTNCVLAPEFQE
                     GGFYKVKDALDMLSHHKEQALVEVSYKKFKELKKLVSEGDDVPAN"
     gene            complement(23726..24403)
                     /locus_tag="PC466_003855"
     CDS             complement(23726..24403)
                     /locus_tag="PC466_003855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HEAT repeat domain-containing protein"
                     /protein_id="HDF2771161.1"
                     /translation="MDINWENIDNLEDYFITYLLYKESKTVSQISKIRNISSTEAGEQ
                     LIQAKLKIKEMQKDDFEASKDILDKFLELDKIKRLDFMDSLDDEKMVYFKRKVFKRIL
                     VEKNAEDLIVLIWATGELKDDRFLKLLHQLTNHRHSDIRRITYSAIRKIESPSSREVL
                     QKGLYDKNAQTRQYCAKALSKLGDENSLKILQQLKDKNKNFEKEYVLRAYDEAIKSLE
                     NAKNLKK"
     gene            complement(24411..25694)
                     /gene="hflX"
                     /locus_tag="PC466_003856"
     CDS             complement(24411..25694)
                     /gene="hflX"
                     /locus_tag="PC466_003856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HDF2771162.1"
                     /translation="MKEIQEKALLVGLNLTTIVKKNDDIDTSESMEELKELTKAAGAE
                     VVGSLIQNKHSVDAAYYIGKGKVEEIRAYSDSLDATLVIFNDELSGAQIRNIENVVGR
                     KVIDRTTLILDIFAQRALSKEGKLQVELAQLKYRLPRLYGMGGEMSRTGAGIGTRGPG
                     EQKLEIDKRHILNKAADIRRELKEVKKNRETQRVKRLKSNIPIVALVGYTNAGKSTLL
                     NELIKTHKDYEQEKEVFVKDMLFATLDVTLRKALLPNKKEFLVVDTVGFVSKLPHDLV
                     EAFKATLEEVQYADLILHVIDATNTSYELQKSTTEGVLKELGVNDKKHILVYNKVDKL
                     ELDIYPKSQEDIVYISAKQGINMDKLLNMIEIALMENTYSVSLMLPYERGDIFSRIKD
                     KYNVENFEYGENGITLDVNFDEEDFNIYREYILEK"
     gene            25911..26171
                     /locus_tag="PC466_003857"
     CDS             25911..26171
                     /locus_tag="PC466_003857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich small domain-containing protein"
                     /protein_id="HDF2771163.1"
                     /translation="MGENYKFFNHKDCEFFPCHKTNKPEEFNCLFCYCPLYALGENCG
                     GNFKYTDKGIKDCSSCMLPHKKDNYNYIMGKFQDLVKITSKK"
     gene            complement(26282..26488)
                     /locus_tag="PC466_003858"
                     /pseudo
     CDS             complement(26282..26488)
                     /locus_tag="PC466_003858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888584.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1461 domain-containing protein"
     gene            complement(26631..27824)
                     /locus_tag="PC466_003859"
     CDS             complement(26631..27824)
                     /locus_tag="PC466_003859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDF2771164.1"
                     /translation="MKEKRRDNKGRILHTGESQRTDGKYLYKYVDAFGNTKYVYAWRL
                     TPTDPTPKGKREKTSLRELEQQIRRDIEDGIDSTGKKMTLCQLYAKQNEQRANVKKST
                     MKQREQLMRLLKEDKLGARSIDTIKPSDAKEWALRMKEKGFSYNTINNHKRSLKASFY
                     IAIQDDCVRKNPFDFKLSEVLENDTKEKVALTEEQEQALLSFIKTDNVYHKYYDDVLI
                     LLKTGLRISELCGLTVADIDFKNEVVIIDHQLLKSKEQGYYIETPKTKNGTRQVPLSR
                     ETIQAFQRVMKKRPKAEPFVIDGRSNFLFVNHKGKPKVAIDYNALFVRMVKKYNKQHK
                     DNPLPHITPHTLRHTFCTRLASKNMNPKDLQYIMGHSNISITMNWYAHASIDTAKSEV
                     QRLIA"
     gene            complement(27903..28109)
                     /locus_tag="PC466_003860"
     CDS             complement(27903..28109)
                     /locus_tag="PC466_003860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HDF2771165.1"
                     /translation="MSNAQDIPVWEKYTLTIEEASKYFRIGENKLRRLAEENKDAGWL
                     IMNGNRIQIKRRQFEQVIDKLDAI"
     gene            complement(28102..29244)
                     /locus_tag="PC466_003861"
     CDS             complement(28102..29244)
                     /locus_tag="PC466_003861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HDF2771166.1"
                     /translation="MNNLEFALEMKNKRLASGLSQGELASLTHVSRYSINRFENGKAN
                     ASKETQNIILRCLNYYICDKPFYLLVDYLSVRFPTTDALEIIRKVLGMKADYFIHYDY
                     GYYGYKEHYAYGEIKVMASDDEHMGVFLELKGAGSRNMEYVLQAQNRDWYSFLNRCLD
                     CGGVIRRFDLAINDMCGLLDIPVLSEKYKNGGADCRCKNYENVQGGKLSGKNRNLAST
                     LYIGSKASTKYFCLYEKQKEQATKKKHTDIINRFEIRLRDKKAVQAVEELLLTYNPHG
                     LVFYLITDFVQFPDYPLWEIFISHDSLPFEMNPVPVNMERTLQWLERQVMPSIVMIEE
                     IDRLTGSNYMKMIDECTHLSEKQEMLVEQMCTDIADVIESEGVFYE"
     gene            29756..30391
                     /locus_tag="PC466_003862"
     CDS             29756..30391
                     /locus_tag="PC466_003862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2771167.1"
                     /translation="MEGYAMKISHLGNNIQTIRKFRGMKQQELADKIGINMQSLSKIE
                     RGLNYPAYETLEKIMEVLDVTPNELLSGEWKYVNQSEKEVCQFLRAEERLNAELKHGH
                     YDNFFDSEEEWLEYELEKLREYITDYINGKSIEASDLYPIKEFIQHLKFQKLLDRYDD
                     LYSMDMFGESIEGHKYKTPYQVVKMINPNSKEDMELLREVLRNNNFDDEDE"
     gene            30867..30983
                     /locus_tag="PC466_003863"
     CDS             30867..30983
                     /locus_tag="PC466_003863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HDF2771168.1"
                     /translation="MILKYPENICMLCMPMVMHKNPSDKSIYHWDFYALLGF"
     gene            30999..32918
                     /gene="tet(M)"
                     /locus_tag="PC466_003864"
     CDS             30999..32918
                     /gene="tet(M)"
                     /locus_tag="PC466_003864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HDF2771169.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYTSGKLLEALELEQEESIRFHNCSLFPVYH
                     GSAKNNIGIDNLIEVITNKFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLH
                     LRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRKKIENPHPLLQTTVEPSKPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLG
                     KVQMEVISALLQEKYHVEIEIKEPTVIYMERPLKKAEYTIHIEVPPNPFWASIGLSVA
                     QLPLGSGVQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            33037..33204
                     /locus_tag="PC466_003865"
     CDS             33037..33204
                     /locus_tag="PC466_003865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HDF2771170.1"
                     /translation="MCPVCGNKTRLKIREDTELKKFPLYCPKCRQENLIEIKQFKVTV
                     ITEPDAKTQSR"
     gene            complement(33264..33617)
                     /locus_tag="PC466_003866"
     CDS             complement(33264..33617)
                     /locus_tag="PC466_003866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2771171.1"
                     /translation="MRKKEDKYDFRAFGLAIKEARLKRGLTREQVGALIEIDPRYLTN
                     IENKGQHPSIQVLYDLVSLLHVSVDEFFLPANNLVKSTRRLQIEKYMDSFTDKELSLM
                     ESLASGINEARNIED"
     gene            34122..34421
                     /locus_tag="PC466_003867"
                     /pseudo
     CDS             34122..34421
                     /locus_tag="PC466_003867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
     gene            34424..34753
                     /locus_tag="PC466_003868"
     CDS             34424..34753
                     /locus_tag="PC466_003868"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2771172.1"
                     /translation="MGISLFLELPAIVSYWVVTVMCFVAMGVSTMFVVQIYTLVQTQT
                     PPQLVGKIMATLVAVAMCGQPIGQMVYGILFDVFIQETWVVMFVASIASIMISIYSKR
                     IFQKLEI"
     gene            34980..35399
                     /locus_tag="PC466_003869"
     CDS             34980..35399
                     /locus_tag="PC466_003869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009588541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDF2771173.1"
                     /translation="MRTSSFEHIVRLQFNSLMLIVIKNKVKSRNRQLARHSKREVLFC
                     EIAETKQVERGTIDTCFYDCVSFKVLHFTIYVSDETLGTVLHRLSEKQRSAILLRYFQ
                     GMNDRKISELYHVSRSAICSRRTRGLRKLKMLLSEGK"
     gene            35404..35643
                     /locus_tag="PC466_003870"
     CDS             35404..35643
                     /locus_tag="PC466_003870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004609551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2771174.1"
                     /translation="MSKDYGYPSFELICKASSGDEMAVKEILKFYDGYISKLCLRPFY
                     HSESGKIIMQVDEELKGEIHTDMMKAILKFEIGVK"
     gene            complement(35822..36283)
                     /locus_tag="PC466_003871"
                     /pseudo
     CDS             complement(35822..36283)
                     /locus_tag="PC466_003871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888584.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
     gene            complement(36312..37862)
                     /locus_tag="PC466_003872"
     CDS             complement(36312..37862)
                     /locus_tag="PC466_003872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018592108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HDF2771175.1"
                     /translation="MLVVENVSHGFGARTILENVSFRLRKGEHIALVGANGEGKSSFL
                     NIITKKLMPDAGNIKWSSRATVGYLDQHTVLSKEKTIREVLREAFKHMFDLEQEMIAM
                     YDKMGEASDDEMSKLLEETAEIQTILENSGFYMIDAKIQEVANGLGLGEIGLDKDVTD
                     LSGGQRTKVLLTKLLLENPTILILDEPTNYLDEEHITWLTKYLQEYENSFVLVSHDIE
                     FINNTCNVIYHMENGELNRYKGNYDEFVRLNDIKKRQEEQAYDKQVEERKRLEDFVAR
                     NKARVATRGMANSRQKQLDKMEILERPKEKIKPTFAFKDARAASKIIFETENLVLGYD
                     EALTKPLNFHLERGKKIALKGMNGIGKSTLLKTLLGIIKPFEGNVKLGDYLEVGYFEQ
                     ESSRENSNTPMDEVWSEFPGLTNFEVRQALAKCGLTNEHITSQMRVLSGGEAAKVRLC
                     KVMLKNINFLVLDEPTNHLDVEAKDELKKAIKEFKGTVLLVCHEPEFYSEIVDDVWNI
                     EDFTTKIV"
     gene            complement(38064..38948)
                     /locus_tag="PC466_003873"
     CDS             complement(38064..38948)
                     /locus_tag="PC466_003873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDF2771176.1"
                     /translation="MKKYRLLVTCIIAMGIIIIGTSNPVSNFYKTTNLISSGNITNEK
                     ADKDENSNKNNKDKNEDKSNSKSNKDKSSEDKSSDKKNKIQKNKKLLICIDPGHQGKG
                     DSNLEPVAPGSSSKKARVSSGTEGIATKKPEYVLNLEASLVLKSILESKGYNVIMTRE
                     THDVNISNSERAILANDKKADMVVRIHADSLNNSSKTGASILIPEKDGKYTAPIYEES
                     NKCAEFIKQNMEQSGIQINGIVQRGDLTGFNWSKVPAVLVEMGFMSNYNEDQMMSNPD
                     YQRKMMQCIADGLDAYFK"
     gene            39176..40183
                     /locus_tag="PC466_003874"
     CDS             39176..40183
                     /locus_tag="PC466_003874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S55"
                     /protein_id="HDF2771177.1"
                     /translation="MQLKNFHFKNNTLSKKTNLAKSKFTIVLTFLFLLYFFSNNLIYA
                     QNLQKNEPEYLIPIGNVLQIDAELKNIIVRNPGEASPFRLGDAIVKVNNSEVDGYSDF
                     ANTLNALPEEKQVSILLNRGGQLITMKTTKHILEKISFNNLLSGFATLTYINPDTSEF
                     GAVGHPISVGNARKIPIKTGSISTTKHLNIEKSYKGSVGCINAKRENIIGSFTENTDF
                     GIRGQINNFDISNLKKYKVASLDEVKLGKAQIILQDNFNKCKKYNIEIIDIENQKHPE
                     SKSFKIKITDKKLLAQTGGIVQGMSGTPIVQDNKIIGAVSHAIENDPAVGYGVFIKWM
                     L"
     gene            complement(40395..41093)
                     /gene="yunB"
                     /locus_tag="PC466_003875"
     CDS             complement(40395..41093)
                     /gene="yunB"
                     /locus_tag="PC466_003875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein YunB"
                     /protein_id="HDF2771178.1"
                     /translation="MNRIVDRKTKNEFRKIIAIFLVILFLSVFIGSFIYIDKTLRPTI
                     TVLAETKALELANRSINKAVAEMVEGKINYEDLMDIQLDNNGKITMIQANTIMMNEIA
                     SAIALEIQDELKKDKTASSYIPIGTALGSPILAKYGPKLEVSIEPIGTVSVNFKTEFE
                     SSGINQTRHRIYLEAQTQVKVVIPLITSTKQIKAQIPICETIIVGDVPESYVNIPEKN
                     LGNVLPNTGKNTNK"
     gene            41307..>43834
                     /locus_tag="PC466_003876"
     CDS             41307..>43834
                     /locus_tag="PC466_003876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase domain-containing protein"
                     /protein_id="HDF2771179.1"
                     /translation="MNNDNDKNGNKIRRKKVSSSGNTNKPINRTSANKTRSTKNKKKS
                     KKSDKFKKLRVFGIVFLVLLVVGTAGTAGLVFASLRDVTPVTEAVLDKQTNQTTTIKY
                     ANGKTLSTAPSVNKKTPVPLDKISPYLQHAVIAIEDERFYEHKGVDIKGLFRSVLKTL
                     TGTKQGGSTIPMQVSKMLLTTEQQTIPRKIKDIYYAHEMSKTVSKDKILETYLNNFFV
                     GRGLAGAEAGARGYFDKSAADLTLAESALLAGSTKNPSRFSAYKTSKLEGNETKEDLE
                     NKLLFFVNTTDDDLDDPTQVDFDMIEKIKSWELISNDTYRQLKAGTLVVRKAVSNPEA
                     KKRQEIVLKKMLELKYIKQSEYDEAIKAKIEIKLPQSSDKVSSSVEDLIESEVINALM
                     EQGHTNDEAQNLFYNGGLIVNTTIDPKMQDALEEEFDRNSNFPGHMVGPDGVSQPQAA
                     MVILDYKNGEIRALAGGRNISGRKTLNRATNPHQPGSSIKPLAIYTPAIDTLKITQST
                     ALSDSRGGYKFEENNKWNPRTTTAGHGSMSLRKALAKSSNTIAVKTAEMLGDSYDECV
                     DIMMDYLKNFGITTLKNNHSGSSEASDRKFPSLTLGGMANGITPLQMAAAYGTLANQG
                     VYVEPSIFTTITTFDGQLLVKNAPEEHKVVDPEVAYVVTDMLESVITEGTGGVATLPK
                     GMPVAGKTGTTNSAYDAWFVGYTPYYVGATYIGDDAGRKDDSGNTIKRREVPHGSTST
                     AKLWEKIMEKIHANLTVTEFEVPKNVYFTKINLEDGGKQSSGSKAAFIEGTAPTKVSS
                     QPSSEDTKKPDNNQPEENNNNNNNTGDNGGGSTPPDNGGNNGGGS"
BASE COUNT        14057 a         7900 c         5925 g        15952 t
ORIGIN      
        1 aaatcaaata tattttcatc atttcaacaa tgaaaaagag tcttatctat agtttgagac
       61 agccctttat ttcttatgta aaatatgtaa aaaggcgtcg ctctattctt agtgcgacac
      121 ccacgattaa tttaagtcta ttaaaatttc acttactata gattttgcat cctctattat
      181 atactttgga tcaacttcat aaaattctct atctataaat ctatcaatct tctctatgct
      241 ttctatagaa tcacttgtaa caaataacac tatagatgca tcttctatat cataaataga
      301 aagttcattt tttatattat cattttcttg aatttcataa actaaatcaa atcctaaatc
      361 atttgcagct gtcttaagag aatttaaact tctttcactt tcacaaactg ctactatctt
      421 tttattcata tttcaaatac ctttctaatt ctactccggt acaatcatca ctatacattt
      481 tgcttgttta actacacttg ctgttactga acctatcatt cttgtaagac cttttttagt
      541 agattttgtc ataactataa aatctacatt atcttctttt gcttttctaa ttatctcatc
      601 tcctggatat ccaaaagtaa aatgtacttt aacatcatac tctcccatta tctctgctgc
      661 tttatccaag attcttcttc ctaaattttc agaatttttt atctcttcag ccagggatat
      721 gccatcaata aatactagtt cttttacatt cattatttct acttcaactt catctttttt
      781 aaatattcct tttataaatt ccaaagaatg catacttctt tctgtcccat caattggcac
      841 taatattttc tttttattca tgtcacatct tcctttctca ctttaggata attaaataaa
      901 atataataaa tctttactcc attaattaat attaataata tgtataataa atttaatatt
      961 tattattgtg ttaattttat aatatatcgc tggcagtgtc aatgaacaaa gttgtaatta
     1021 aaaaaataaa gggtgttaac ttgtaaaagt attttctttc aacaaatttt taaaaacatc
     1081 ttctggaact ggtttagaaa aataataccc ttgcaaatat tcacactcca tagctattaa
     1141 atcttcagca cacttaatgg tttcaacacc ttctgctaca gccttcatat tcaatttatt
     1201 tataagagct ataatcgtct caactgtaag cttatgccta ctatcttcat tcatagacca
     1261 aatcaaactc ttatctaact taattactga aaatggtaaa gaaagcatat tagtaactcc
     1321 agaataagca attccaaaat catcaagtgc aaacttaaca cctaaatcaa ttaatctttc
     1381 cattgtttct ttaattatat taaaagagcc catagccaca gtctcagtaa tttcaagttt
     1441 aaatttagtt ggtgatacat tatatttatt cataagataa agtaaatcat cagctaagtt
     1501 tttttgcata cattgtacta cagaaagatt cacagctata ttatccaatt ttaaattttc
     1561 aaactcatca ctagctataa atctacatac cttctcaaag actactaatc caattgagtt
     1621 aatcaatcct gtttgttctg caattggaat aaattcatca ggaggtataa aacctaactc
     1681 tttgtgttct agcctaagta atgcctctgc tgaagtaaac ctgcccctgc tattagaaaa
     1741 tataggttgg tagtacactt caaacccatc attttttaat gcttctttta aacaattttt
     1801 aataacatgt ttcttcttta tcttttcact tatagacgca tctgcataaa caactcgcct
     1861 tgactcagaa cgttttgctt catgtataga gaaatctata gcaacaatta catcttctgt
     1921 cgtttctgca ttttctgggt aataaacaac agcaatacta gttgctaaat taaaacttat
     1981 ctcttctact agccaaggct ttttaaatct ttcttctatc tttctgataa tatcatctgg
     2041 ttctatacct aattgactat tgacaacaat agaaaatata tctcccccta ttctatatac
     2101 atggtttaca tcatgtatct gaatcaaata ttttccaact tcttttagtg caatatctcc
     2161 attttttgtt ccaaaagttt cattcataaa cttaaaatca tcaagcgcaa ttgtaataat
     2221 aaatcctgat tgttcagtat tgatattcaa atctagctct tgaataaaag attgtctatt
     2281 gagtacacca gtaaggtcat caataataag acctcgattc tgcatagaaa gatatgtcaa
     2341 aagtaaacta catgcacatg cagttcctgt aagaagatac tgtaaaaaaa ttgcctgtaa
     2401 gataattgcc acaattgaaa ctataagaaa acctctaata gcccatattt ttgattcatg
     2461 cattgctttt ctatatttaa aagataaaaa tgctgaatat attgcataaa agaaaaaaga
     2521 tgcaaaagtt gcaacatatc cacaaccccg tatataacct gtttcttttg acaatccaaa
     2581 tagaatatgc gtaaaaggat ttgtaataga taagattata caaattataa gtggtataga
     2641 taaaaataat aatctttttt tcatatacct tatatcttga taaataatag ccataacata
     2701 aaatgataca agagctgctg gtattggcaa taacaataag tatatctgat tcaataaaaa
     2761 agtaataaaa attggaattt tgtctatatt atttagacaa aatgaaccta aaatatttga
     2821 aagtataaat aaaaatgaga atattaaaag tgcacaatat attttgtttt gtaaagtagg
     2881 tataaattta cttctaaaaa agtataccat taaaaaaata actataattg cagaaaaaat
     2941 ctcatattct atatgccata ccataaactt ccctcgctat tgacgtttga ttttaaatat
     3001 tttaataata taatttattt ataattatat tataattcat cttgagtaat tttatggaaa
     3061 attttttatt ttataacttt tacttcaaat ctccattaaa accctaaatt tactctaatc
     3121 attattatgc atatagaaat taagcaaata gttcttttgc cttagtagca attctttcac
     3181 caaatattat agccttctca tcttgtaact ctggaccttc aattgaatgt acatgtccta
     3241 aatgtataaa tggctttcct aaagaaccac ctccagaata cacaagcatc cctttaacca
     3301 tcaaatgtcc tactatagta agtatcgcaa catctggacc tccacatata taatcacatg
     3361 tagcaaaaac agctcctaat tttccagcta aattaacttt ttttgaatct tcatcaaacc
     3421 atttttttac ttcccaagtt gtatttgcta aataagtagg tgttccaaat attactgctt
     3481 tactttcatt taaataatct aaatcaatat tatcaagtct cataagcttt acatctactc
     3541 catccacctt tttagctcca tcttctatca gcttagcgac cctttctgtg tttccacttc
     3601 ttgtttggta taatactgta atcttcaact ttaattcccc cttatctaat aaaaataatt
     3661 tattatacat caaattatat cactaatttt gctgtcctac aaagagctag tcgattattt
     3721 ttttattaac tatttcccat aaaaaacacc tacatttatt actttaaaaa acacctaaac
     3781 tcacttttaa cttgcttatt tcaatctcaa ctatatctga tatatcttca aaagacatgc
     3841 ctctatcata aagttttcct gcaattttga tttttgcatt ttcttctcct tttttaatca
     3901 atgctctgtt ttctttttct attacatttc taacatatct ctttgcaaat ggttcattat
     3961 tatcatatag agccttgtat ttttccttat ctccttttac aaaactaagt gctcttttat
     4021 cttgttttat agcttctgta caaatttctt ctgtttgttc ttttacaaat tttaatgcca
     4081 ttccatattg tcttactgcc tttaagcata taccaacagt ctgttccttt acaaattcta
     4141 atgccattcc attttgtctt actgctctta aacagattgt ttctgtttga ttttttacaa
     4201 atttcaaatc aagcccattt tgtctcactg cttccataca tatttcttct gtttgatttt
     4261 ctacccattt tagattatag ctacaatgct taactgcttc catacatatt ttttctgttt
     4321 gatttttcac tcttgccaat ccaaattcgc tgtttctaac tgcttctata catatttctt
     4381 ctgtttgttc ttttacatac tccaaagccg caccattttt ttcaacggct cttaagcata
     4441 actcctctgt ctgattttct atatatttta atgctgttcc atcttggtta atagccaaca
     4501 tgcaaatttc ttctgttgac tcttccacaa attctaacat tctccaatct tgtttaactg
     4561 cttctataca tattttttct gtctgattct gaacacattt tattgcatta caattttgtc
     4621 taacagcctc tagacatatc tcttctgttt gattttttat gtatattaaa ttcaatccat
     4681 tttttcttac tagctctaaa cattcttctt ctgttttatt atcaaaatcc tcagtatcta
     4741 ttgattcaaa tatatcattt ttatcttcat gcatatctta gactcacccc ttataaattt
     4801 tataaaattc aataaattta ctctcaattt tattctatca aagaatataa aaatttttga
     4861 gtcttgtttt ttttcataaa atcatttgta tgttaaaaaa taaattaatt actctaattc
     4921 cagtatacaa tgcccaaaat atgtggtata ttttaactat aatatattta tatatattat
     4981 tgtcagaata tttaaagtta aatttatata aaacatcttt atttatatat cacttatatt
     5041 tggatatatt ttcttttttt agttttcggg ttagtaaggg gttagtagtt taggttttca
     5101 caggatatta tttttacaat tagttttatt ttcgtgtaat ttatatatgt tgtaattaat
     5161 aaaactaaat atgatttaaa taattccttg ggataaattt aataaaactt agattcctta
     5221 tctaagctta aaatactaaa attattggga ggatataaat aatggaccaa attaagcgtt
     5281 tacatgaatt gcaacaaaaa tcatatttaa ctaaagaaga atttgaggaa ttaaaaaata
     5341 acacatatat tgaaagattt gaattaagag atgagtgcga taactcttat atttatacat
     5401 tttacactaa cgataaatgt aatgatataa aatttataaa atcacaattt atcgttacac
     5461 ttataaaaat tggtttccta tgtgagtgtg gtggtgtatt tagacaaaag aaaatagttg
     5521 atgaatatga ttatggatac aatgctatat ataagtgtga ttcttgtggc aaagaacttg
     5581 ataaagaagt agaaaattat gactaaataa caaaaaagct attcaaaata ttttttataa
     5641 atgctagata aaatttactc taaatttaaa ctaaactatc ccctcttagt agacagttaa
     5701 aatataaaaa actgtcaata actaagaggg ttttgttata tcctaaatta aacataataa
     5761 tcttagatat caaaagatac tgaaatatag atagtaatta taaatacaat aaaaagtact
     5821 aatgattgac attagtactt cacatctact tttacacgtt ttaactgcat aaaacagttt
     5881 atacagttcg ctttgaataa gggcgctttt tttagcattg ccttaattca agttatctta
     5941 attatttaat tcaatttcat acttttttat tttcttatat aaaagactct tgtgtattcc
     6001 cataacctct gctgccttag aacatttcca attatacttc cttaacacat caataattaa
     6061 gcttttttca taattctcaa ccatttcatg aattgaacaa ttgctatcca cattacattg
     6121 agctactctg ctgatattat ccatcttaga tggaaggtca cacatcataa tgaccatatc
     6181 atcacttaca gcataggcac tttttattac attttgtagt tctcttatat ttcccggcca
     6241 agtatagtta ataaaacaat ttttaacctt atcacttaaa accttcaatt ccttgtattc
     6301 aacatttaat ttgtttaata tataatttgc tagcaataaa atatcatctt gcctgtcctt
     6361 caattccatc atatgaatgt ttattacatt taatctatag tataggtctt ctctaaataa
     6421 tccctcttca accattttac ttaaattctt tcttgtggca gagattactc ttacatctat
     6481 ctttatagtt ttaagacctc ccactggttc tatctcactt tcctgaagaa cccttaaaag
     6541 ttttgcttgc atggtcaaag gcatgtcacc tatctcgtct aaaaagattg taccattatt
     6601 tgcaactaaa aacttacctt ttttaccacc cttttttgct cctgtaaaag ctccttcgtc
     6661 ataaccaaat agctctgact ctaataattc ttctggtatt gcagcgcagt ttatactaac
     6721 cataggttta tctgacctac tgctattatt gtgaattgct ctagcaaaga cttctttacc
     6781 tgtgcctgtt tcacccgtta aaagtactgg aaagtttgtt ttagaagctt tcacacctgt
     6841 tttcttaagt tctatgaagt ctctattttc acctatgagc ttgtcaaaac cgcagttatc
     6901 cttaaactgc tctttataat attggagctc catatattct gacattaatt ttttagctac
     6961 atcaaatgat tgcaatctaa atttaacttg agctactcct gcaactactt ctccattgtc
     7021 attttctaca taagacctac ttactattac acttttttct tttgtatttc cacctgaata
     7081 atgatgtata gctccttctt cacagtactt atctttcata acatctagca tttttgtatt
     7141 tggtataata ctttgtatat tttgtcctat tatatctttt ctttcttttc ctaaaaagtc
     7201 acaatattta tcattaatat ctattattac tccacttgta tttacaacaa taaaaccatc
     7261 atcagtcata gataatattc ttgcaaatat atccttatac cactgctctt tcattgtttc
     7321 atctccccac tataaccttc agcaaaaata ataagtctta caatacaata ttataagact
     7381 tatcattcta catattcaat gttttctaaa agttacctat ttaatgattc tatcatttca
     7441 ggtataattt catataaatc tcctactatt ccatagtcac atatactaaa aataggggct
     7501 tttgcatctt tatttatagc aactatatat ttagaatcac tcatacctgc taagtgttgt
     7561 attgctccag atattccaca tgcaatgtat agttctggtc taacagtagt tcctgtttgt
     7621 cccacttgat gagaatgttc tatccaccct gaatctactg ctgctcttga agcaccaatc
     7681 tctgccccca atttatcagc caattctttt ataagctcaa atccttctgc tctttttaat
     7741 cctcttcctc ctgatactat tattctagca tcagttagat ttacagattt cttttcttgt
     7801 ggaagtacct ctactaatct agttctaatc attttttcag taagttctgg agtaacaact
     7861 tctaaaattc cagtctctga ttcgtttctt acagcttttg ccataactcc tggacgaact
     7921 gttgacatct gtggtctatt ttttggacaa acaatagtgg ccattaaatt tccaccaaat
     7981 gctggtcttg tttgtaataa cttattatct gttgaatcta tttcaagttt tgtacagtca
     8041 gcagttagac ctgttccaac cttacctgca attctaggcg ctatatctct tcctatagaa
     8101 gtagcaccaa ccaatacaac ctctggcttt tttctttcga ttaaatttgc aattgaaatt
     8161 gcatatccat cagtagtgaa atctttaaga agagggtcat tgatgtaata tactttatca
     8221 acactatagt gaagtaattc cttcacttct ttctctactt catatccagc tatcacaact
     8281 tcaagctctt ttcctaattg gtcagcaagc tttcttcctt caccaataag ttctatcgta
     8341 acaggattaa ttttgccttc cctttgctcc cctattaccc aaacaccatt ataatcattt
     8401 aaatttatac cttgattaac ttttgctctc atcatcttaa cactcctata ctagtttcaa
     8461 atcgaatagt atttctatta gtttctcagc tttttctttt ttatttatac cttctattat
     8521 ttcattatgc ttgtctttaa ctggtgcaaa agacttataa acatttgtag gtgaaccctt
     8581 taatccaatt tgagttgtat caacatctaa atctgcaagt gttaatacag taatcttcgc
     8641 atctccatta ttataagctt ctaagattcc ttttacactt ggatatcttg gattgtttaa
     8701 ctcttttata gcagttaata aaactggcat ctttgcttct attaaataat cccctgtctc
     8761 tgtataacga gttactagta atttgtcatc ttgaaccttt acttcttttg cataagtaac
     8821 ttgtggtatc cctaaaaatt ctgcaacctc tggtccaacc tgagctgtat ctccatctat
     8881 agcttgtctt ccgcagaata ttacatcata ctttccaacc ttttctatag cagcagcaat
     8941 aattgtagat gtagcccaag tatctgaacc accaaaagct ctatctgaga ttaaataagc
     9001 ttcatcagct cccattgcca aagcttcttt taaagcactt ttagcttgag gaggtcccat
     9061 gcttataacc ttaatcactg ctcctagttc atctttcatt tttagagctt cttctaaagc
     9121 atttctatca tctggattga ttatacttgg tacaccatct cttattagag tacctgtctc
     9181 tttatttatt ttaacttcat tagtatctgg aacttgcttt aagcaaacaa ctatattcat
     9241 tcttttcctc ctatcctagt actgctcttg aaataacaac tttgtgtatt tctgaagtac
     9301 cttcgtaaat ttctgttatt ttggcatctc tgtacattct ctctaatgga taatccttca
     9361 tatatccata tccaccatgg atttgaaggg ctagatttgt aacctctctt gcagtacttg
     9421 acgcattgta ttttgccata gcagcttctt tagtgtgttt ttctcctcta gctttcaaat
     9481 ctgcagcata atatactaat aattttgctg attccaccat tgtcgccata tctgctatat
     9541 accattgaat accttgcaac gctgaaattg gcttgccaaa ctggactctt tctttagaat
     9601 atttgatact ttcttctaaa gccccttcag caattcctac agcttgagct ccaattccaa
     9661 ttcttgctcc atctaaacaa gtcatagcta tattaaatcc tttgccttct tttcctaata
     9721 agttagactt tggaactcta cagttatcaa atattaactc tgcagtttct gaaccatgaa
     9781 tacccatttt ttcttcaatt tttcctattg aaaaacctgg agtacctttg tcgacaatga
     9841 tagcagacat tccctttatt ccctttgatg ggtctgtcag tgcaaatatt attaatgatt
     9901 ctgcttgacc tccaccagaa ataaaacact tagttccatt taaaacatat tcatccgttt
     9961 cttcatcaat aattgcagtt gttgcagctc ttgcagcatc tgaaccagca ttaggttcag
    10021 ttaaggcgaa agcacctaca cacccacctt cagccatcat tggaaggtat tttttctttt
    10081 gttcctcagt accaaatttc aaaatagctt gagcatatat tgtgtgtatt gataatattg
    10141 ctgcagatgc tgcacatttt ttggcaatct cagtaacaac aattaccttt tctatatctg
    10201 tccctccaga accactatac tctacaggtg ttccaatgcc attaaatcct attttagcca
    10261 ttttgctaaa aagctccctt ggaaaaatac ctgttttatc tgtttcagca gctattggtg
    10321 ctatttcatt ctctgcaaat tcttttgcta ctctttgaag cattaattgt gcttctgtta
    10381 atctaaaatc cataaaattc cctcctattt attaacatac ttcacatgtt tattaacata
    10441 tttcacatgc ttctttattc attgttacaa ttccagattc aattagagct tctatatcag
    10501 aatcactgta tccaagttct ctcaatatct catctgaatg ttctcctata agtggagcat
    10561 cacaagtcat gttaacttca atatttccaa atttaactgg agtggatgca agcattgtct
    10621 tatttccatt tttacttgta tgctcatata tatagttatt agcaatagcc tgttcatcag
    10681 tcactacatc attaacatgt tgaatttttt catgagctat atcagcagca gtaagttttt
    10741 caaccatctc attttgagta aactttgcaa attcaccatc caaaatatta ataagttctg
    10801 tagcattttt cttactttct actgaagatg caaatttctc ttcttttatt aagtcttctc
    10861 ttccaaataa tctacaaagt gcctcaaaat atctttcatg ctctaaaata cttaagaata
    10921 tccactttcc atccttacaa cgataagaat ttattactgg tgaaatagca ttttttctag
    10981 tttttggata ctcatcacta aactgtgtag atgctaataa agatgatgca ttccatattg
    11041 cttgcccaaa taaagatgcc attacttttt gtccttttcc agtcttagct tgctggtaca
    11101 aagctgcaca tattcctcca gataaactac aagaagttgt tgcatctcca aaggctatag
    11161 gtggatttat tggacttgta tctttttctg ctatatcaag catagcccca cttcttgccc
    11221 aaaaggcaac tgtatcaaat cctgcattat ccttagcagg tccaaaatcg ccaaaaccat
    11281 ttatctgacc ccagataagg tgtggatgct ttttacttaa tgattcataa tcaagaccta
    11341 gtctttttaa tgctcctgtt ctataacttg aaacaaatac gtttgcttca cttaaaagct
    11401 tatccataat ttcaattcca gtttcactct taagatttat agacaaacct cttttatttg
    11461 aattatatgt gctgtaaaaa ggattattat aatcatctat tggcattgtc attgttgccc
    11521 ctgtctttct tcctgggtct ccaaagcttg gctctacctt aataacgtca gcaccccaat
    11581 cagctaatat tttagaagtc cctggacctg ctacaaaata cgttaggtca ataaccttaa
    11641 ctccctctaa tggtttattt aacactttca attcctcctt atatggtcaa tttgttattt
    11701 taaatacata tttatagtat taaaacatga aatttattgt atatattttg aaaattgatt
    11761 ttataatatc aaaatataat ttataccttt tatcttttct cttatggcaa tcccgggaac
    11821 attgtaaaca gtaggactgc tactatggtt ccaataaacg gagttaaaac agttacccag
    11881 aatattggca tataggcatc cttatgtgtt tctttacaca gaccatttgt tacagtaaca
    11941 atatatccat tgtgtggaag tgaatctaat gctgctgatg aaattgccat agtcctagtt
    12001 aatgctgcag cggaaacacc cttggctaaa aatactggtc caagaagtgg agctgcaatt
    12061 cctagtccac ctgaagctga cccacaaata cctgcaataa ctgtagttcc aactgcagcc
    12121 cctgcaatag gaggaccagg aatattagtc atggcattaa ctatgaagtc aaaaccaact
    12181 gctgatttta ctactgaacc aaatgcaact acagcacaag tattacatat tgctactact
    12241 gtagttttac atgcatcacc aacatgtcca actattttag tattatcttg atatttattt
    12301 aacaataaat atactaataa agctccaata aatactccca cctcaattgg tactatcgct
    12361 tttccattaa cttttacatt aattattaaa attgacacta tcaatggaat taaggcaatt
    12421 acaccattag gaccattttc tctcttagaa ttagttgctt ctgcttcatc aaatatatct
    12481 gattcatgtg ctataaaatg accaccattg gctttttctt ttgaaaccat tttgtacaaa
    12541 atggtacttc caactataaa cattactgca catgatataa aaccatttac tgctccggcc
    12601 ataatatctg tccctaatgt tgatgctgga acaatattct gaatttgtgg tgcccctggt
    12661 gcaaccatag caaaagttga gcatccaaaa gtcaaagctg ctggtataaa tcttcgtggc
    12721 aaatcagctt ctttaaaaat ttctaaagct atcggaaaca ctgcaaaact tacaacgaaa
    12781 acacttactc caccataggc taatattcca caagctattg gaatagaaag tagtgcttta
    12841 tccttaccaa tccatcttac aatcatctta gcaatagatt ttgctccacc agtaatctcc
    12901 attatttttc ccattaatgt ccctgttagg aaaataaaga aatttgcctg aagaaatcca
    12961 acaaatcctg tcatataatc cactttaagt gcatcataca catttaggct tcctgttata
    13021 gcaactaatg atgaacatac aattgctata ataaaaatat ttattccctt cataaccatt
    13081 acaactagaa gagatagagc tatgataatc cctactaaac ttataattac tcccgtattc
    13141 ataaattaac tccttttaaa attaaactat atgtattttt tcacgaaatt tagattttga
    13201 atatattcta cattgttcca atttagttat aatagctact tattttcaaa aactggcttt
    13261 ctcttttcta taaatgcatt cattccttct tgcttatctc ttgtagcaaa agttaaacct
    13321 gcaatatctt tctctagttc aagagcattc tttaaatcca tatctatccc tttgttaata
    13381 acaacttttg catatcttat tgctattggc gctttttcaa ctatttggtt catcatcttc
    13441 atagactctt ctaaaagtaa atcacttgga accactttat taataagccc aatagattta
    13501 gcttcttctg catttacttg tctccccgta aaaattaact ctttagctat tccagttcca
    13561 acaagtcttg ataatctttg agttccacca aaacatggaa taactcctaa attaacttca
    13621 ggttgtccaa atatagcctt ttctgatgca attctaatat cacaactcat agcaagttca
    13681 catccaccac ctaatgcata tccattaact gctgctatta ctgttttctc aagagcttca
    13741 attttatcaa aaattccctg agcataacct gcatattttc tgccttcctc acttttatag
    13801 ttttgcatct ggcgtatatc agcaccggct acaaaaactt taccttctcc agtaataata
    13861 actcctaata ttgcctcatt ttctgatact acatcaataa cttgtgatag ttccctaaga
    13921 gtgtcactat taagagcatt taaagcttta ggtctattta tagtaataac acagactttg
    13981 tccttaacct ccaccttaag attgttcaaa ttttccatta cagattccat catattcccc
    14041 ccattataca ttgttatttt ttctacattt cttgttaata taaaatagca agtactatgc
    14101 caatcaccat tgaagttctt tatttttagt aaaaaattgt tatttttaat aaaataaacg
    14161 aaatatacat aaatttcact aaatttttaa taattttcaa ctttaaaatt gattaaattg
    14221 taattcacag aagaattttt cttcaataaa actcataaaa caatattttt gtctcatttt
    14281 cgagaaaata cttaaaaaac gcagtctcat ttttgagaat gcagtctcat ttttgatatt
    14341 tccattaaaa taatttaaat agcatctcta taagtttatt ttcactaaag tagtctttat
    14401 tcaacataat taggtagttt attttctatt aatttaaatt gttaatactt tagtttagta
    14461 catatctatt ctgataatat aaagttctta atgaaaatag gaaaagccac aaagactcaa
    14521 tgtctaagta gcttttccca tcttaaatgc ttctgacaat tctatatttg atttacagta
    14581 ttgatttaat attttttgat attattctaa ctgaacctcc catgactaaa gtcacaagtg
    14641 tgtttagcta ttttttaatc aaataactcc attttctttt aaatctttta ttttatcact
    14701 atcaaaacca agccaaccat tataaatctc ctcgttactt tcccctagag atggtgctgg
    14761 catatcaatt ttagcttttg ttgtcatcaa cttaactgga tttccattga ctttcatatt
    14821 tcctataata ggatgactaa tatctacaat catttctctt gcttttgcta tatgttcatc
    14881 tgttgtaaca caatcaagat tatagatagg agcagcagga actccagcct ctgatattaa
    14941 gtcaactgct tcttttattg tatgcttaac agaccatttt tctatttctg gtttaagagc
    15001 cttgtaatgt tcacaacgct taagatttgt tttaaatctc tcatctatta aaaggtcttc
    15061 tctaaaaaga acttttttac ataacttttc aaaaagtttg tcattaccac agcctattac
    15121 aaaacttcca tcacttgcct taaaagagtc ataaggatag gctgaagcat atctattacc
    15181 cataagttca ggttgtcctg aatcaaagta tctctgtata ccagtttcga gagacgatac
    15241 aacagaatca acgagggaaa catctactct ttgtcctttt cctattattt ttctagcgtt
    15301 gagtgctgtg agtataccaa tagttaaatt cattccacct agtacatcac ccatagcatt
    15361 accaactctc gttggttctc ctccttcttg ccctgttata ctcataagac cacccattgc
    15421 ctgtgcaata atatcataac ctggacgttc tgaatatggt ccataacatc caaatcctga
    15481 tacagctcca taaattattt gattgttaac tttagccaac tcatcataac ccagacctaa
    15541 cttttccatt acacctggtc tgtaattttc tactacaaca tcagcatgtt ttaccatttc
    15601 taaaaatata ttttttcctt cttctgattt aaggtttaga gtgatacctt ttttatttct
    15661 atttatattt gcatagtata aactctctcc atttacaaaa ggtccaaaac ctcttgtatc
    15721 atcacctttt cttggcatct ctatttttat aacatcagct ccaaaatccg ccaacatcat
    15781 tgtacaatat ggacctgcaa gaactcttgt aaggtcaagt acctttatat tgcttaatgc
    15841 tccttttttc ataacttccc ctccaaatta tattatattg attaatatta aaaattaaat
    15901 ttaatgaatt attttcagtt attataatta gttcattaaa tgtgttattg cattaaatga
    15961 taatattgat actactgcaa taaccaataa gccaactgca ctcataatga aaagctgtac
    16021 aaaaacctta ttttgttctt ccttattaaa gtctttctta cttgaaccca tagctgctaa
    16081 aatcaatgcc ccaccagtag aaagtgggct tacaccagca agagaacctc caacaccgac
    16141 tgcagcaata agtgctagtg ggtctactcc tccaactgcc ttagctatat caacacacat
    16201 aggcatcata gttggataaa ctactgctaa agcagaacta accatagaca taagtcctgc
    16261 tgaaatactc ataattggag tagctgtttt actattcatc agtgatgata atgcattact
    16321 catcaagtca atacctcctg ctgcatctac gattgtcatc attgcaccta ctccaagaac
    16381 cattactatc gtgctccatg gaattgattt gatacattct ccttcatcag caatattgaa
    16441 aaaaataagt acagctgaaa ctgcaaaagc tgcaagccca acattcatat caaaaattat
    16501 gataaaagca atcataacta ctatgcttat tagagaaatt atctgcttta tattaaattt
    16561 ttctatttgc ttactatcta taacatttat aggtttttta agtttatatc ctttgaaaat
    16621 tataaacaat actattgaaa atacaattgt agaaagagtt tgacaggcta agatagtagg
    16681 cataacattt tcaattccaa ccccttctgc aacggttgtt ataatttgac cttctggagt
    16741 aataggagtc atacgacctg ccattaatcc acattcacct ataagtgcaa gcattacagg
    16801 attataacca accgttatgg ctacaggaac agccattgct gggataattg caagtgctgg
    16861 aattgcccca ggtccaacac cagcaacaac aaatcctgct ataaaaactg ctataggtat
    16921 aagccaaaca cgtttaccag aagcagctac aattttttct gcaacaagct ttaatgctcc
    16981 tgttgagttc actattgcaa agagtagtgt tataccaaca agtgtagtaa acattgagtt
    17041 gcttatagct ccataaagtt ctttatcatc cattccaaaa attctaacag ctatgacacc
    17101 aatagctaga gccaaaatac ctgcattatt cttacgtaca aatgcaataa taataactcc
    17161 taaaaataaa agtaaagcta taatatccat actaatcccc ctcaattttt ttatttgttt
    17221 tattagataa tgtattttat aatttatctt ttttatcaat aaatctattt taccaatcag
    17281 catatttttt taatcaacat atttttttaa tcgattaatc aatagaacta acaattacaa
    17341 ctatcagact ttatatttac atgatgacca ctatatactc catttacaaa actcttctga
    17401 tactttgata attcaagaag tttaacaaaa tcaactcctg tatcataccc catacgttca
    17461 agcatatata ctaaatcttc agttgcagta ttgccagatg ctccaggagc aaatgggcat
    17521 cctcctaatc ctccaagtgt agactgaaca gtagtaattc cagattcaat agccacaaga
    17581 gtattaacca ttcccatatt tctagtatca tgaatatgta cctgccatct gcactctggt
    17641 aaagcttcaa ctaatgcact aatagtttct cttacttgct tagggtcagc aatccctatt
    17701 gtatctgcta gatttatctc cctgataccg ttttcccaaa ggcgtttagc aaatcttatg
    17761 gcatcttcaa tttttggtaa accttcaaaa ggacacccaa atacagtagc cattccaata
    17821 catatattca tgtctggata agtattcatt atttttttaa gctcatcaat agactcttca
    17881 tgggtacgat ttatattttt tttattatga gtttcactca aagatataac ataggatata
    17941 tctcttatac cacactccca tgcaacttta gcaccatata aatttggaac taatgcataa
    18001 agtttcacat caggatattt ttctacacaa taagttgcta cttcttttgc atctttcatc
    18061 tgaggtattg cttttgggct tacaaatgaa ctaatttcaa gttgtttaat ccctgaagca
    18121 ataagaccat caataatctt aagcttttta tcagtttcta aaaactcttt caggttttga
    18181 aatccatctc taggaccaac ttcaaatata tttaccttac tcataccttt tcccccttta
    18241 cagtcacatt gcaagctagc attgcatgtt cctgcttaac tttgcttaat ttgagttaat
    18301 aataagctta tttaagcata ttataatcct ataaactaaa ttatgtcaac ataagtaaga
    18361 agttttttta aatttattta ttctaatcct gtaaaatatg caccttgtag aatattgttc
    18421 tttagttgaa tatatgttaa gattattggt ataagcaaat ttaagcaact atttaaggag
    18481 gattttatca tggcaacaat caaagatatt gcaaaagact gtggtctttc ttcagcaact
    18541 gtctcgtacg tcttaagtgg taaaggaaat gaacgcagga ttccgctaca tacacaagag
    18601 cttatattaa attcagctga taagcttgga tataaacgct ctactcctat taaacataat
    18661 aatattaaaa tagcttttta ttggcaggat gagggatttg agttggcatc aaccaatata
    18721 cttcaagcaa taaaccacat aatttcttta gaacatttaa acataaatat catcatacga
    18781 ccttacaaag ttggtcatct atgtgatgat gaatactttt ttgcaaataa ttattatgat
    18841 ggaattgttt taacaggtat caatgctgat gatatagaat atctagtaaa aaataaacct
    18901 aaaattcctg tagttgttgt aaatcgtgaa atacctggtt tttcaagtgt atctattgat
    18961 aatgaggaaa ctggtcgtat agcagcttta catgctattc aaaatggtaa aaatgatatt
    19021 gctgttgtat tcaacccaac ttcctttaca tgtatgactt taaggggtaa atctttttta
    19081 aaaacatgta aagaacatgg aatacatcta tcagattcta tatattattg ttctaataaa
    19141 atagatagtg gatatgatat tgctcaaaaa atgcttgcaa aaaattcact aaaaaaagta
    19201 attttttgta atcatgatgt tgtagctctt ggtatgatga atgcatttca tgaatctgga
    19261 attgtaattg gagaggatat tcaaatattt gcagcaagta atggaccttc acgactaatg
    19321 gcaagaagta ttcctccttt gacagttata gatttaaaaa tggaagagac agcagaacgt
    19381 agtcttagga tgattattga tacagtaact gggcgtataa atggtattca gcaacaagtt
    19441 atatacccat caattattta tagacaatca agtccagctc aaaatttact ttaaatttct
    19501 taacctataa atataaaaac accccttacc tatacttaca tattattatg caaatatagg
    19561 ttagaggtgc gtatgtctat tttagtaatt tcttattcta taaaatttat cacatgttaa
    19621 aattgattca atgcttataa atttcaatat gcttatacta tttattctac ttcccagtta
    19681 tgatatatat cttgaacatc atcatcttct tcaagcatat caactaattt attcatcatt
    19741 tttaaatgag attcttcagt caatacagtc gtagtttgag gtatcatctt cacatcagca
    19801 gatataaact catatccttt agcttttaac tcatcacgaa cactagaaaa atcttctggt
    19861 gtagttatta tttcataacc atcttcttct gttatgaaat cttcagctcc tgcttctaat
    19921 gcaacatcca tcaattcttc ttctgaaact ccatctccta aaccaactaa tatttgtcct
    19981 tttttatcaa acataaaaga cacacatcca ctagttccta agtttcctcc gtttttgtca
    20041 aaatagtatc ttacgttacc agcagttctg tttttgttgt cagttaaagt ttctactata
    20101 acagcaactc caccaggtcc atatccttca taaactatag tttcatagtc ttctccagcg
    20161 cctgctccag cacctttagc gatagctcta tctatattat catttggcat attatctgcc
    20221 ttagcttttt ctatagctgt ttttaacgct gcattgtact ctgggtctgc tccaccttct
    20281 ttagctgcaa ctgctattgc tctagcatgt ttagtaaata tctttgctct ttgagcatct
    20341 tgtttacctt ttctattaat tatattacct atacgtccca tatttccact ccttaatacg
    20401 tacaattaat tattctaatt ttcatcactt gtaaatttta tcacaaatct tataaatagt
    20461 aaattagaac ttaggaggtt gtgcaggcgt ttttctcttg tgttcactta atctatgaag
    20521 tctttctatt atctcttggt ctcttttagg aacttcatcc aatctacctt ctaacacagc
    20581 atctatcata ttgtaagtag ttcccatttc atcttcatct gtttgacctt cccaaagacc
    20641 tgctgaagga gctttgttta ttaaatcttc atgaacacca agctcttttg cccattcata
    20701 tacttctcct ttagttaaat ttgcaatagg taaaatatca actccaccat caccaaattt
    20761 agtaaaatat cctgtgtgta tttctgcagc attgtctgta ccaacaacta aatatcctag
    20821 attgttagca attgtataaa ttgtactcat tcttactctt gctcttaagt tcgcatctgt
    20881 catctttaaa tattctgctc tatataaatg tttatctttt aaatttccta ctaccatgtc
    20941 taatatagca ctttgtggtt ctataaggtc taaatcaagg tattctatat cacatccctc
    21001 tataacctta agtgcatctt ctctatcttg aggattactt tttatgctca ttataactcc
    21061 catagagttt tctggaaatg cctttttaat taaattagca actactgccg aatcaattcc
    21121 tccagataca ccaacaatta atccttttgc atttgcctca ttaaccttat ttataagcca
    21181 ttctacagtt ttgtctattt gtatttttat atttgacatt gttatctcct ctcaaatttg
    21241 ctactttgtt ttaatatatt ataccatata ttaatatgtt gttttaatat gttttttttt
    21301 atgcaaaatt aaacaaacat gaaagattat atttaatctt attttatata aatataattt
    21361 gcctattttg gtaaaactat ttcagaaggt gatttttatg aaaaaaactg atgatttaaa
    21421 gaaaaaatac tttgatttta acttaaaaaa tacgataatt ggagttttta caggatttat
    21481 aaatggagtt tttggttctg gaggaggtac tcttttagtt ccaatattaa atgacatcgt
    21541 taaggtagaa gaacataaat ctcatgcaac tgctctttct ataataatat tcttaacgac
    21601 agcaagttct gttttatatg tatctaaagg tacttatgat gttaacttaa caattaaagt
    21661 tgcagttgga agtattcttg gtggtattat aggagctaaa ttactaaata aggttactgg
    21721 aaagtttctt agaatttctt ttggaataat tatgataatt gcagcattaa ggatggtgtt
    21781 ttaatgttat ttgctctaat tggatttttt gcaggaatta ttggaggaat gggaatgggt
    21841 ggaggaacaa tccttatacc tgcactcgtt ttacttgctg gcatagacac taaaatagca
    21901 caaagcgtaa atttactttc atctatccct atgacactta tagcacttgc tatacatata
    21961 aaaaataaaa atgtaatttt taaattggtt atacctatag ctgtgtttgg ggttttagga
    22021 gctgtatttg gttcactatt agctaattat ctgtcttcag atatattaaa aaaaatattt
    22081 gggatatttt tacttttagt cggtttattt gaagtaaaaa aaggattctg tgcaaaatcc
    22141 gataaaaagc cattaaattg atttagatta aatcaattta atggcttttc acttaaaaat
    22201 actaattggc tatttgaggt attaactatt ctaataacct tttagattat attaaaattt
    22261 ctccattttg ttcagacaaa taaaattcct ctcctaaaat tatttttcct gttccatttg
    22321 ttatatcaat cattttttct gataatttct ctacatcttc taatcttgaa tacactacta
    22381 tctcaacatt atcctcatat acagtatctt ttataaaata ccccaaattc attaactcat
    22441 tttgcacttt tccaagttga gtatagtcta tcttaacctt aacttcttga tacattacct
    22501 tataaattat cttacctgct tcaagtccca atttagcacc ttttgtataa gctctaacta
    22561 gaccgcctgc acctaatttt gttcctccaa aatacctagt aacaacaacc actacatctc
    22621 tcaaatcttc tttttttata acctctaatg taggtattcc agctgttcct tgtggttctc
    22681 catcatcact atatctttgt atattcatat ttttacctac agtataagcc cacacattgt
    22741 gagttgcatc tttatgcttt ttctttattt catttataaa ctctaatgct tcttcttcac
    22801 tctttatagg cttagcatat ccaataaaaa cagacttttc aatagttatt tcatctgttc
    22861 caaattcatg taatgtcctg taattgctca ttgtatttcc tcctatttta atcattttct
    22921 aatatacaca tcaaattata tatctataaa attattctat ttaaaaataa atggactttt
    22981 aatacttctt taatcaatat cataagacaa ttatataata aaattgtata ctttttaatt
    23041 tttattttaa atatatctta ctgattttaa atataaacta ctaaagctct aaattgataa
    23101 atcataattt aaagagacta tataatttac gcttaaaact gcttcaatta aaaaaggaag
    23161 gggctatccc ttcctcagaa tcctctaaat tcacaattaa tttgctggaa catcatcgcc
    23221 ctctgaaact aatttcttta attccttaaa ctttttataa gatacttcta ctaaagcttg
    23281 ctctttatga tgtgataaca tatctaaagc atcctttact ttataaaatc caccttcttg
    23341 aaattcagga gcaagtacac aattagtgtt acaagcttcc ataacatacc acattattgc
    23401 attacaaact tcttgttgtc tacttcttga gaaaaattca tacatagtat cgccagccac
    23461 atctatcatt ttagcatcta tgccagtttc tactttaact ctttgaacag cactctcata
    23521 tggaagtcct cctccaagta tctttccttt tggaagtgtc cattctcccc tatcattttt
    23581 tacaataagt actttattag cataaaacac tactccacct gcacaacgtc ttactatcat
    23641 ttgaaacccc tcccattaat ttatttatta ccttgttaaa ctctagaaat acatcattaa
    23701 gtaaacaaat tgctttaata aaaaattact ttttcaaatt ttttgcattt tccaatgact
    23761 taatggcttc gtcataagct ctaagcacat attctttttc aaaattctta ttcttgtctt
    23821 tcaactgctg taaaatcttt aaactgtttt catcccctag ttttgaaaga gcctttgcac
    23881 aatactgtct agtttgtgca tttttatcgt agagaccttt ttgcagtact tctctactac
    23941 ttggtgattc aatctttctg attgctgaat aagttattct tctaatatct gagtgtctgt
    24001 ggtttgtgag ctgatgaagc aactttaaga atctatcatc ttttagctca cctgtcgccc
    24061 aaattaaaac aattaaatct tcagcatttt tttccacaag gattcttttg aaaacctttc
    24121 tcttaaagta taccattttt tcgtcatcta agctatccat aaaatcaagt ctcttaattt
    24181 tatctagttc taaaaattta tctaaaatat ccttagatgc ctcaaaatca tctttttgca
    24241 tttcctttat ttttaatttt gcttgtataa gttgctcacc tgcttcagta cttgaaatat
    24301 ttctaatttt actaatttga gatactgttt tagattcttt ataaagaaga taggttataa
    24361 aataatcttc aagattatct atattttccc aatttatatc catattcaac ctatttttct
    24421 agtatgtact ctctatagat attaaaatct tcttcatcga agtttacatc tagcgttatg
    24481 ccattttccc catactcaaa attctccaca ttatatttat cttttattct actaaatata
    24541 tcacctctct cataaggtaa catcaagctt actgaataag tattttccat taaagcaatt
    24601 tctatcatat ttaatagctt atccatattt atgccttgtt ttgcagaaat atacacaata
    24661 tcttcttgac ttttaggata tatatccaat tctagcttat ccactttatt atatacaagt
    24721 atatgttttt tatcatttac accaagttct tttaatacac cttcagtcgt acttttttgc
    24781 aattcataac tagtatttgt cgcatcaatt acatgtaaaa ttaaatctgc atactgtact
    24841 tcttccaatg ttgctttaaa cgcctctact aaatcatggg gaagtttact tacaaatcca
    24901 acagtatcta ctactaaaaa ttctttttta ttcggcaaaa gagcctttct tagagttaca
    24961 tccaaagttg caaaaagcat atcttttaca aaaacttctt tttcttgttc ataatccttg
    25021 tgtgtcttta ttaattcgtt caaaagagta gattttcctg catttgtata cccaacaagt
    25081 gctacaatcg gtatatttga ctttaaacgc ttaactctct gtgtctccct attctttttt
    25141 acttctttaa gttcacgcct tatgtctgct gctttattaa gtatatgtct cttatctatt
    25201 tctagttttt gttctccagg acctctagta ccaatccctg cacctgttct actcatctca
    25261 ccacccattc cataaagtcg tggcaatcta tattttaatt gtgctaattc aacttgtaat
    25321 ttaccttctt tactaagtgc tctttgagca aatatatcta aaattaaagt agttctatct
    25381 attacttttc ttccaacaac attctctata tttctgattt gagcaccaga taattcatca
    25441 ttaaaaatta ctaaagtagc atctaaagag tcactatagg ctcttatttc ttctacttta
    25501 ccttttccta tataataagc tgcatctaca gaatgtttat tttgaattaa gctacctaca
    25561 acttctgccc cagcagcttt tgttagctct tttaattctt ccatagattc actagtgtct
    25621 atatcatcat tttttttcac tattgtagtc aaattcagac ctacaagaag tgctttttct
    25681 tgaatttctt tcacttaatc acctcatttt ttgttataaa acatattcta attacaaaat
    25741 acacttacat aatttttaca ttatttttct gttgactaat tataccatta atactatgat
    25801 taataatact atattatcga ctattcataa aattatttag tataattata ttatcaccaa
    25861 aatcttatat agtataaaaa atttaaattt tatttaatta ggaggaaaat atgggcgaaa
    25921 attataagtt ttttaatcac aaagattgcg aatttttccc ttgtcataaa actaataaac
    25981 cagaagagtt taactgtcta ttttgctatt gtcctttgta tgctttagga gaaaactgtg
    26041 gtggaaactt taagtataca gataaaggta tcaaagattg cagtagttgc atgttacctc
    26101 acaaaaaaga taattacaat tacattatgg gcaaatttca agatttagtt aaaatcacta
    26161 gtaaaaagta atttctatta gaaatagcta tgcataaata tttatcgact actcttagtt
    26221 taaatattat tacatagcta tttttattgt ataaccttta atataattcg tttttgctat
    26281 cttattttat tttgaaagat ttatataatc tatacattac aaatagtaag atacttgcta
    26341 acaaaattaa tattaaaatc atcattcctg agtgaaaaaa aaattcctct ggcaatatat
    26401 ttataactgg gtctaaattt ggattaaata tccaataatc atttctaaat aataatttca
    26461 tttaaattat atatgccttt ttgactatct ttttatatct tctcaaatgt ccgcaaagcc
    26521 ttattttatc ggctctacgg gcattttgct tttgtggtaa acctcacata tctaggtcta
    26581 tctttttata ttttcgctat caaacgtggt taaaatcgtg gtaaatactt ctatgcgatt
    26641 agacgctgaa cctctgattt tgcggtatct atggacgcat gagcatacca gttcattgtg
    26701 atactgatgt ttgaatgtcc catgatatac tgtaaatctt tcgggttcat gttcttgctt
    26761 gccagccttg tgcagaacgt atggcgtagc gtatgcggtg tgatatgtgg caagggattg
    26821 tccttgtgtt gcttgttgta tttctttacc atacggacaa ataaggcatt gtaatcaatc
    26881 gcaactttgg gcttgccttt atgattgaca aacagaaaat tgctccgtcc gtctatcaca
    26941 aatggttctg cctttgggcg ttttttcata acccgttgaa atgcctgtat tgtttctctg
    27001 cttaatggca cttgccttgt tccgttcttt gttttaggcg tttcaatata atagccctgt
    27061 tccttgctct ttaataactg gtggtcgata atcacaactt cattcttgaa atcaatatcg
    27121 gctactgtca gtccgcacag ttccgagata cgaagtccag tctttaacag tatcagcaca
    27181 tcatcataat acttatgata cacgttgtcc gtcttaataa atgacagtag ggcttgttct
    27241 tgttcctctg tcaatgccac tttctctttg gtatcatttt ctaggacttc acttaacttg
    27301 aaatcaaaag ggttcttcct tacacaatcg tcttgtatgg cgatatagaa tgacgctttt
    27361 aacgagcgtt tatggttgtt aatagtattg taggaaaagc ctttctcttt catgcgtaac
    27421 gcccattcct tagcgtcaga gggttttatc gtatcaatgc tcctagcacc caacttgtcc
    27481 tctttcaata accgcatgag ctgttcccgt tgtttcattg tgcttttctt cacgtttgcc
    27541 ctctgttcgt tctgtttggc gtagagttgg caaagcgtca ttttcttgcc tgtgctgtcg
    27601 ataccgtcct caatatcccg tcttatctgc tgttccagtt cacgaagtga ggttttttcc
    27661 cgttttccct ttggtgtcgg gtctgtgggt gtcaatctcc aagcatacac atattttgta
    27721 tttccaaatg cgtctacata tttatacaag tattttccgt ctgttcgttg gctctctcca
    27781 gtatgcagga tacgtccttt gttatcccgt cttttttctt tcatggtgtc tgctcctttc
    27841 cttgttggaa agagccttga tatgacttgt gttcatcata acacatacaa ggctcatttg
    27901 cattagattg cgtccaattt atcaataacc tgttcaaact gtcgtcgttt aatctgtatg
    27961 cggttgccat tcataatgag ccagccagcg tccttgtttt cctctgccaa gcgtcttaac
    28021 ttgttttctc cgatacggaa atactttgac gcttcttcaa tggtaagggt gtatttttcc
    28081 catacgggaa tatcctgtgc attactcata aaacaccccc tcactttcaa ttacgtctgc
    28141 tatgtccgta cacatttgtt ccacaagcat ttcctgtttt tcagaaaggt gggtacattc
    28201 atcaatcatt ttcatgtagt ttgagcctgt cagcctgtcg atttcctcta tcatcacgat
    28261 tgacggcatg acctgtcttt ccagccattg cagagtgcgt tccatattga caggtacggg
    28321 gttcatttca aaaggtaaac tatcatggga aatgaatatc tcccacagcg gatagtcggg
    28381 aaattgcaca aaatcagtaa taaggtaaaa caccagccca tgagggttat acgtcaataa
    28441 cagttcctca actgcctgta ctgccttttt gtcacgcaga cgaatttcaa aacggttgat
    28501 aatatccgta tgtttctttt tagttgcctg ttccttttgt ttttcataca ggcagaaata
    28561 ttttgtgctt gcttttgagc cgatataaag ggtgcttgct aaattgcggt tttttccgct
    28621 tagtttaccg ccttgcacat tttcatagtt tttacagcga caatccgcac cgccattttt
    28681 gtatttttca gataaaacgg gaatatccag cagaccgcac atatcgttga ttgccaagtc
    28741 aaaacgtcgg ataacaccgc cacagtcaag acagcggttc aagaatgaat accaatccct
    28801 gttctgtgcc tgtaaaacat attccatatt gcgtgagcct gcccctttta attccaaaaa
    28861 tacgcccatg tgttcatcat cagaagccat aaccttgatt tctccgtagg cgtaatgctc
    28921 tttatagcca taatatccat agtcataatg gataaaataa tctgctttca tgccaagcac
    28981 ctttcggata atttccaatg cgtcagtcgt tggaaaacgg acagacagat aatcaacgag
    29041 cagataaaaa ggcttatcgc agatatagta attcagacaa cgcaggataa tattttgtgt
    29101 ttccttgctg gcgttggctt ttccgttctc aaagcggttg atactatatc ttgatacatg
    29161 ggtaagactt gcaagttctc cttgtgaaag accgcttgca agacgtttat tcttcatttc
    29221 aagtgcaaat tctaaattgt tcattgtatt cctccaatcc cacaatagcc ttgaaatacc
    29281 tgtaaaccac tattcaaaag aatgtgaaat tactatcttc ttaaaactcc tcattactcc
    29341 ttacagcttt ggggttgtat ggtttttgac ttgtcttttg tgaaatagtg cccccctgtt
    29401 agataacggg ggcacagaca aggctcgcag gctcgccagc cgacaaagca tttcttcccc
    29461 ttgacacaag gtgtcatggc ggtaagcctg agaggcttcc gccaccgtgt cagaaatact
    29521 ttgtcagcaa gttctgtttt gccttttcta acaagttcca tttcaaccga tattcatatc
    29581 tacggattta atcagatagg tatttctttt tgaatgtttt tatatttcat tctattgtgc
    29641 ttattcgatt acaagaacat agtaattctt atatgcttat ttgtcaatat ctttttttgc
    29701 ctttacaaat catattaagc atgatagact tataatagcg aagatataac gagatatgga
    29761 gggttatgca atgaaaataa gccatttagg aaataatata cagaccataa gaaaatttag
    29821 gggaatgaaa caacaggaac ttgcggacaa aatcggtatc aatatgcaga gcctttccaa
    29881 gattgaaaga gggttgaact atcctgccta tgaaacgctg gaaaagataa tggaagtgct
    29941 ggacgttacg cccaatgaat tgttgtcggg agaatggaag tatgtcaatc aatctgaaaa
    30001 ggaagtctgt cagtttttaa gagccgaaga acgtctaaat gcagaactga aacatggaca
    30061 ctatgataac ttctttgaca gcgaggaaga atggctggaa tatgagttag aaaagttacg
    30121 ggaatatatt acagactata tcaacgggaa aagcattgaa gcgtccgacc tttacccaat
    30181 caaagaattt atccagcatt tgaagtttca aaaattatta gaccgctatg atgatttata
    30241 cagtatggat atgtttgggg aaagcataga gggacataag tataagacac cttatcaagt
    30301 cgtgaaaatg ataaacccga actcaaaaga agatatggaa ctgttacgag aagtattaag
    30361 gaataacaat tttgatgatg aggacgagta acttttttcc tcttgcgaga agatacagca
    30421 aacaaaaagc ccgatcaaga gtgcaaagca ccaccaatgg tggcaaagct cttgacaggg
    30481 ctttttcttt tctgttgtgg gcaatcaaga ggaagaaagg gataaaatct gatttgtggt
    30541 aaatcaggca aaggcaacgc aggtatctca atttgatttg gtacttgaaa agaacgggag
    30601 taattggaag attatagaat aacaaatatt ggtacattat tacagctatt ttgtaatcac
    30661 gtactctctt tgataaaaaa ttggagattc ctttacaaat atgctcttac gtgctattat
    30721 ttaagtatct atttaaaagg agttgataaa tatgcggcaa ggtattctta aataaactgt
    30781 caatttgata gtgggaacaa ataattggat gtcctttttt aggagggctt agttttttgt
    30841 acccagttta agaatacctt tatcatgtga ttctaaagta tccggagaat atctgtatgc
    30901 tttgtatgcc tatggttatg cataaaaatc ccagtgataa gagtatttat cactgggatt
    30961 tttatgccct tttgggcttt tgaatggagg aaaatcacat gaaaattatt aatattggag
    31021 ttttagctca tgttgatgcg ggaaaaacta ccttaacaga aagcttatta tataacagtg
    31081 gagcgattac agaattagga agcgtggaca aaggtacaac gaggacggat aatacgcttt
    31141 tagaacgtca gagaggaatt acaattcaga caggaataac ctcttttcag tgggaaaata
    31201 cgaaggtgaa catcatagac acgccaggac atatggattt cttagcagaa gtatatcgtt
    31261 cattatcagt tttagatggg gcaattctac tgatttctgc aaaagatggc gtacaagcac
    31321 aaactcgtat attatttcat gcacttagga aaatggggat tcccacaatc ttttttatca
    31381 ataagattga ccaaaatgga attgatttat caacggttta tcaggatatt aaagagaaac
    31441 tttctgccga aattgtaatc aaacagaagg tagaactgta tcctaatatg tgtgtgacga
    31501 actttaccga atctgaacaa tgggatacgg taatagaggg aaacgatgac cttttagaga
    31561 aatatacgtc tgggaaatta ttggaagcat tagaactcga acaagaggaa agcataagat
    31621 ttcataattg ttccctgttc cctgtttatc acggaagtgc aaaaaacaat atagggattg
    31681 ataaccttat agaagtgatt acgaataaat tttattcatc aacacatcga ggtcagtctg
    31741 aactttgcgg aaaagttttc aaaattgagt attcggaaaa aagacagcgt cttgcatata
    31801 tacgtcttta tagtggcgta ctgcatttgc gagattcggt tagaatatcg gaaaaggaaa
    31861 aaataaaaat tacagaaatg tatacttcaa taaatggtga attatgtaaa atcgataagg
    31921 cttattccgg ggaaattgtt attttgcaaa atgagttttt gaagttaaat agtgttcttg
    31981 gagatacaaa actattgcca cagagaaaaa agattgaaaa tccgcaccct ctactacaaa
    32041 caactgttga accgagtaaa cctgaacaga gagaaatgtt gcttgatgcc cttttggaaa
    32101 tctcagatag tgatccgctt ctacgatatt acgtggattc tacgacacat gaaattatac
    32161 tttctttctt agggaaagta caaatggaag tgattagtgc actgttgcaa gaaaagtatc
    32221 atgtggagat agaaataaaa gagcctacag tcatttatat ggaaagaccg ttaaaaaaag
    32281 cagagtatac cattcacatc gaagttccac cgaatccttt ctgggcttcc attggtctat
    32341 ctgtagcaca gcttccatta gggagcggag tacagtatga gagctcggtt tctcttggat
    32401 acttaaatca atcgtttcaa aatgcagtta tggaggggat acgctatggc tgtgaacaag
    32461 gattgtatgg ttggaatgtg acggactgta aaatctgttt taagtatggc ttatactata
    32521 gccctgttag taccccagca gattttcgga tgcttgctcc tattgtattg gaacaagtct
    32581 taaaaaaagc tggaacagaa ttgttagagc catatcttag ttttaaaatt tatgcgccac
    32641 aggaatatct ttcacgagca tacaacgatg ctcctaaata ttgtgcgaac atcgtagaca
    32701 ctcaattgaa aaataatgag gtcattctta gtggagaaat ccctgctcgg tgtattcaag
    32761 aatatcgtag tgatttaact ttctttacaa atggacgtag tgtttgttta acagagttaa
    32821 aagggtacca tgttactacc ggtgaacctg tttgccagcc ccgtcgtcca aatagtcgga
    32881 tagataaagt acgatatatg ttcaataaaa taacttagtg tattttatgt tgttatataa
    32941 atatggtttc ttgttaaata agatgaaata ttttttaata aagatttgaa ttaaagtgta
    33001 aaggaggaga tagttattat aaactacaag tggatattgt gtcctgtatg tggaaataaa
    33061 acacgattaa agataaggga agatactgaa ttaaaaaaat tccccctcta ttgtccgaaa
    33121 tgcagacaag aaaatttaat tgaaataaag cagttcaaag taactgtgat tacagagcca
    33181 gacgcaaaga cgcagagccg ataaaatgag attaatacaa tctcatttta tcggctcttt
    33241 ccgttatgta tggattcttt taattagtct tcgatgtttc ttgcttcgtt gataccgctg
    33301 gctaaagatt ccattaagga tagttctttg tctgtaaagc tatccatgta tttctctatc
    33361 tgtaatcgtc gggtgctttt taccaagtta ttagcaggta agaaaaattc atcaacggaa
    33421 acatgaagta acgatacaag gtcataaaga acttgtatgc tggggtgttg ccctttattt
    33481 tcaatattag ttaagtaccg tgggtcaatt tcaatcaatg ctcccacttg ttcacgagtt
    33541 aaacctcgtt tcaatcgagc ttctttaatg gctaaaccaa aggctctaaa atcatattta
    33601 tcttcttttt tacgcatagt agaccacctc tatacatttt attgttccta ctgaattaaa
    33661 aacaggtata gaaaaacgtg ttatatggtt tataggttta tatttaataa aaagcactac
    33721 taaacgccaa taaaaaaaac cgttatatgg tagtgctatt tacgctgtta aaatattgta
    33781 tattacttcc aaatggcggt ttgttggagg tcaacgtcgc catgaagtac atcatataca
    33841 ataaatttcc ttacattggg ttcttgtcaa aaaaagtcgt ctatctgcaa tagataagta
    33901 cgtccaccaa tgtggtttta taaatcatat agatagaata acagaagcat gtaaacagag
    33961 aaataaatct gtttatatgc ttttttggct attcagaact tttttacaaa gtttatttat
    34021 cagtaatgca acaaatcccc ctttcacatt gggactaaga gtgaaaggag ataaacgagc
    34081 aaggctcact tcctttccta gacagaaagg gggtgagaaa catgaaacca tcttcttttc
    34141 agaccacaat agaaaatcag tttgactata tctgtaaacg tgctatggaa gacgagcgaa
    34201 agaattatat gctttatctt tcaaggattg caaagcgtga ggtgtccttt tcggatgttg
    34261 gcgattatct tgttagccag tttgcgacaa cagataacta ttcaactgac tttcagattt
    34321 ttacactcaa tgggttatca gtaggcgttg aaaatgattt gttgagtgaa gcattacgtg
    34381 agttgccaga caagaaacgt gaaattctac tgctgtttta cttatgggaa tttcgctatt
    34441 tttagaattg cctgcaatag tttcctactg ggtagttaca gtgatgtgct ttgtggctat
    34501 gggtgtatct actatgtttg ttgttcaaat ttacactctt gttcagacac aaacaccacc
    34561 gcaattagta ggaaagataa tggctacgct ggtagcagtt gctatgtgcg gtcaacctat
    34621 tggacaaatg gtttacggta ttttattcga tgtatttata caagaaacat gggttgttat
    34681 gtttgtagct tctattgctt caatcatgat ttcaatatat tcaaaaagaa tttttcaaaa
    34741 gttagagata taatacaagg ggttaaatag tatgttaggc taaaaacaat atataaaaga
    34801 aaatttgaaa tctgctaaaa ggatagtgtt ataaaagaaa gagtaatatt gcagtattta
    34861 aggctcgcac aaatatatgt tttgtgtggg cttttttctt accatttttc tgtatttcta
    34921 aagggtataa acggtattcc gtttatatat ttcagcatta gcagaaaggg ggtgagatta
    34981 tgaggacatc ttctttcgag catatcgtca gattacagtt caattcttta atgctgattg
    35041 tcattaagaa caaagtgaaa agtcgaaaca gacagcttgc aagacattct aaacgtgaag
    35101 tattgttttg tgaaatagcc gaaacgaaac aagttgaacg tggaacgatt gatacctgtt
    35161 tttatgattg tgtatcattt aaagtcttgc actttacaat ttatgtatct gatgaaacac
    35221 ttggtacagt tttacataga ctgtcagaaa aacagcgtag tgcgatttta ttacgttatt
    35281 ttcaaggaat gaacgacaga aaaatttcag aactgtacca tgtatcacgt tctgctattt
    35341 gcagtagaag aactagagga ctaaggaagt taaaaatgct tttgagcgaa gggaagtaaa
    35401 gaaatgagta aagattatgg ctatccctct tttgaattga tttgcaaagc gtcaagcgga
    35461 gatgaaatgg cagttaaaga gattttgaag ttttatgacg gttatatttc taaattatgc
    35521 ttgcgtcctt tttaccactc tgaaagtggt aaaatcatta tgcaggttga tgaagaacta
    35581 aaaggagaaa ttcatacaga catgatgaaa gcaatattga aatttgaaat cggagtgaag
    35641 taatcaactg tataaaaaaa tcgggagata cacagtttcg tgctatctcc cttagtagtt
    35701 ttacggtcat atcaaggctc attcaatcgt ggtaaattcg tggtaagatg agtgtttttc
    35761 tatacttcaa aatgcttgaa tgtatagtgt ttatgcggat aattgaaaat tagatataaa
    35821 atttatgaaa aataataaat gatttttcaa aatttaataa aattggaact gttaataata
    35881 atggcataat tataagtgtt attgatgtag ttttcaagat ttttatattt ttatttttta
    35941 cactcaatat aattcctact aaaaaaacta ccaataataa tttagctaat ttatttatat
    36001 tttgaaatat attcctgact tcttcaaaat gtatcttccc ttgtggagaa gattttaatg
    36061 ttggtaactt gaactcagac acattcttat ttaagttata atcaattaga taatcgtagt
    36121 tcaattttat atcatcttca gataaaccag ataactctga tatatttaag taatcaatgt
    36181 caaaataata aagttgttta aatccaacag taaaattaat aacacctact attataacaa
    36241 tactaataca aactgaaaaa agtacattta gaaacttttt catgaaatcc ccccagcaat
    36301 aagttaaatc actacacgat tttagtggta aaatcttcta tattccatac atcatcaaca
    36361 atttctgaat aaaattctgg ctcatggcat actaaaagaa ctgttccctt aaactctttg
    36421 atagccttct tcaattcatc ttttgcctca acatctaaat gatttgtagg ctcatctaat
    36481 actaagaaat ttatattttt taacattact ttgcaaagtc taaccttagc agcttctcca
    36541 ccacttaata ctctcatttg actcgttata tgttcatttg taagtccaca ttttgcaaga
    36601 gcctgtctaa cttcaaagtt tgtaagccct ggaaattcac tccaaacttc atccataggt
    36661 gtattactat tttcccttga actctcttgt tcaaaatatc caacttccaa atagtcacct
    36721 aatttaacat ttccttcaaa tggttttatt attccaagta aagtttttaa tagagtagat
    36781 ttcccaatac cattcattcc ttttaaggca atcttttttc ctctttctaa atggaaatta
    36841 agtggttttg tcaatgcttc atcataccct aaaactaaat tctctgtttc aaaaattatt
    36901 ttactagctg ctctagcatc tttaaaagca aaagtaggtt ttattttttc ttttggtctt
    36961 tctaatattt ccatcttatc aagttgcttt tgtctactgt tagccattcc tctagttgct
    37021 actctagctt tatttctagc tacaaaatcc tctagtcttt ttctttcttc aacttgttta
    37081 tcataagctt gttcttcttg acgtttcttt atatcattaa gtcttacaaa ttcatcataa
    37141 tttcctttat atctatttaa ctctccattt tccatatgat atattacatt acatgtatta
    37201 tttataaatt caatatcatg agaaactaag acaaaactat tctcatactc ttgaaggtac
    37261 ttagtaagcc atgttatatg ctcttcgtct aaatagtttg taggctcatc caatataaga
    37321 atagttggat tttcaagtag aagtttagta agaagtactt ttgttctttg ccctccactt
    37381 aagtcagtta catctttatc aagaccaatt tctccaagac caagaccatt tgcaacttct
    37441 tgtatctttg catctatcat ataaaaacca ctattttcaa gtatagtttg tatctctgct
    37501 gtttcttcaa gaagcttact catttcatca tcactagctt ctcccatttt gtcatacata
    37561 gcaatcattt cttgctctaa gtcaaacata tgcttaaaag cctctctaag cacttctctt
    37621 atagtttttt ccttgcttaa taccgtatgt tggtctaagt aacctactgt agctcttgaa
    37681 gaccatttta tatttccagc atctggcata agcttctttg ttattatatt taaaaaactc
    37741 gattttcctt ctccattagc accaactagt gcaatatgtt caccttttct aagtctaaag
    37801 gatacatttt ctaatattgt tctcgcacca aatccatgac tcacattttc tactactagc
    37861 atttcaacac ctctcaaaaa aattttacac attctatact ataatatatt ctttttaaac
    37921 ttaaatcaag tattcccaat atttttagtt atatttacga caatttaacc taaaataaac
    37981 ttcttctttg cattatgtac aataaaaaat agagataaaa attaggaaaa taataccaac
    38041 ctaacttttt ctctattcat atcttattta aaatacgcat ccaatccatc agctatacac
    38101 tgcatcattt ttctttggta gtctggattt gacatcattt ggtcttcatt atagttactc
    38161 ataaatccca tttctactaa tacggctggt acttttgacc agttaaatcc agtcaaatca
    38221 cctctttgaa cgattccatt gatttgtata cctgattgtt ccatattctg tttgataaat
    38281 tcagcacatt tattactctc ttcatatata ggagctgtat attttccatc tttttcagga
    38341 atcaatatag atgctccagt ttttgaagaa ttatttaaac tatctgcatg tattcttaca
    38401 accatatctg cttttttatc attagcaagt attgctctct ctgaattact tatatttaca
    38461 tcatgtgtct ctctagtcat tattacatta taacctttag attctaatat actctttaaa
    38521 acaagagatg cttctaagtt tagaacatat tctggttttt ttgtagcaat accctctgtt
    38581 cctgaagata ctctcgcttt tttagaggaa gaacctggag ctactggttc taaattgcta
    38641 tctccttttc cttgatgccc tgggtctata caaattaaaa gttttttatt tttttgaatt
    38701 ttattttttt tatctgacga tttgtcctct gatgacttat ctttattact tttagaatta
    38761 gatttgtctt catttttatc tttattattt ttgtttgaat tttcatcttt atctgctttt
    38821 tcatttgtga tatttcctga actaatcaaa tttgtagtct tgtaaaaatt gctaactgga
    38881 tttgatgttc ctataattat gattcccatg gcaattatac aagtaactaa caatctatat
    38941 tttttcattt tttgctcctt tcttatgcta gacagttatt gtttattttt atttatatga
    39001 atatgtattt attttatcat atacactatt tattttattt atttttatga aaactaaggt
    39061 gttattgagt cagttttcca agcatcaaaa cataattctt gcacaacata atatagaagc
    39121 agcaagaaaa cttcaattct attattaaaa taatttaata agaaagaggt gttttatgca
    39181 acttaaaaat tttcatttta aaaataatac tttaagtaaa aaaaccaact tagctaagtc
    39241 aaaatttaca attgttttaa catttttatt tttattatat tttttctcaa ataatttaat
    39301 ttatgcacaa aatttacaaa aaaatgaacc tgaatattta ataccaattg gaaacgtact
    39361 tcaaattgac gcagaattaa aaaatatcat agttagaaat cctggagaag catctccatt
    39421 tagattgggt gatgctatag taaaggtaaa taattctgaa gttgatggat atagtgactt
    39481 tgccaatacc ttaaatgctt taccagaaga aaaacaagta tctattttat taaatagagg
    39541 tggacaactt ataacaatga aaactaccaa acacatatta gaaaaaatta gttttaacaa
    39601 tttactttct ggatttgcta ctttaacgta tatcaatcca gatacatcag agtttggagc
    39661 tgtaggtcat ccaataagtg ttggtaatgc aagaaaaata cctattaaaa caggttcaat
    39721 ttctacaact aagcacctta atatagaaaa atcttataaa ggtagtgttg gatgtataaa
    39781 tgcaaaacga gaaaatatta ttggtagctt tacagaaaat actgattttg gaataagagg
    39841 tcaaattaat aactttgata tttccaattt aaaaaaatat aaagtagcat ctttagatga
    39901 agttaaatta ggaaaagctc aaataatttt acaagataac tttaataagt gtaaaaaata
    39961 taatattgaa attatagata tagaaaacca aaaacatcca gaaagtaaaa gttttaaaat
    40021 taaaattaca gataaaaagc ttttagctca aactggtggt attgtacaag gtatgagtgg
    40081 tactccaata gttcaagata ataaaataat cggagcagtg tcacatgcaa ttgaaaatga
    40141 cccagctgta ggttatggtg tatttattaa atggatgttg taaataatat aaataaataa
    40201 gttttaagat gttattaagt tattaataat atatttggtc taaaggtact tttatttaac
    40261 ctacagacca aatatattag atattttaca tagtataaaa tataaatttt tattaaaatt
    40321 atattaatat tatttccaaa aattttattt ataaactatt attttgaatt tatttaaaaa
    40381 tatacaactt tatattactt gttggtattc tttccagtgt taggtaaaac atttcctaga
    40441 tttttttctg gaatatttac ataactttct ggaacatcac ctactattat agtttcacaa
    40501 ataggtattt gagctttaat ttgttttgtt gaagttataa gtggtattac tactttaact
    40561 tgtgtttgag cttctaaata tattctatgt ctagtttgat ttatacctga agactcaaat
    40621 tccgttttaa agtttactga tactgttcct ataggttcaa tagacacttc aagtttagga
    40681 ccgtatttag ctaatatagg acttcctaat gctgttccta taggtatgta agaacttgct
    40741 gtcttatcct tttttaattc atcttgtatt tctaaagcta ttgcagatgc aatttcattc
    40801 atcattatag tgtttgcttg tatcatagtt attttaccat tattatcaag ttgtatatcc
    40861 attaaatctt cataatttat ttttccttct accatctcag caacagcttt atttatcgac
    40921 ctatttgcta gttcaagagc tttagtctct gctaaaactg ttattgtcgg tcttaaagtt
    40981 ttatctatat atataaaact gcctataaat acagacaaga aaagaattac taaaaaaata
    41041 gctatgattt ttctaaattc attttttgtt tttctatcta ctattctatt caaaattatc
    41101 ccctcctatt tatttatatg tagctttggc ataattttta taatatttgt caaaaataaa
    41161 taaaataaaa atatagactt tttaatatat tacgtttata catatacaat gtacagaata
    41221 ttatagcaaa ttcatttttt ctattaatta caaaactact cctatttgtg ttataatatt
    41281 gcattaagta aggaggttaa aatcttatga ataacgataa tgataaaaat ggaaataaaa
    41341 tcaggagaaa aaaagttagc tcatctggta atacaaataa accaattaat agaacttcag
    41401 ctaacaagac tcgttcaaca aaaaacaaga aaaaatctaa aaaaagcgat aaatttaaaa
    41461 aactaagagt atttgggata gtatttttag ttttactagt tgttggtaca gcaggtactg
    41521 ctggtctagt atttgcgtca ctaagagatg taactccagt tacagaagct gttttagata
    41581 aacagacgaa ccaaacaact actattaaat acgctaatgg aaaaacattg tctacagctc
    41641 caagtgtaaa taaaaagaca cccgttccat tagataagat ttccccttat cttcaacatg
    41701 ctgtaattgc aatagaagat gagcgttttt atgagcataa gggtgtcgat attaaaggtt
    41761 tatttaggtc agtattaaag acccttacag gtactaagca aggtggtagt actattccta
    41821 tgcaggtatc caaaatgctg ttaacaactg aacagcaaac tatacctcgt aaaataaagg
    41881 atatttacta tgcacatgag atgagtaaaa cagtaagtaa agataaaata ctagaaactt
    41941 atttaaataa cttcttcgtt ggtagaggtc tagcaggtgc tgaggctggt gcacgtggtt
    42001 attttgataa gtctgcagct gacctcactc tagcagagtc agcacttctt gctggttcaa
    42061 ctaaaaatcc atcaagattt tcagcctata aaacttctaa gttagaggga aatgaaacta
    42121 aggaggattt agaaaataaa ttattatttt ttgttaacac aactgatgat gatttagatg
    42181 accctactca agtggacttt gatatgattg aaaaaataaa atcttgggag cttatatcta
    42241 atgatactta tagacaatta aaagcaggta cattagttgt tagaaaggct gtaagtaacc
    42301 ctgaagctaa aaaaagacaa gaaattgttt taaagaaaat gttagaattg aaatatataa
    42361 aacaaagtga atatgatgaa gcaatcaaag ctaaaataga aataaaattg cctcaatcat
    42421 cagataaagt ttcttcatct gtagaagacc ttatcgaaag tgaagttata aatgctttaa
    42481 tggaacaagg acatacaaat gatgaagctc aaaacttatt ctacaatggt ggtctaattg
    42541 taaacacaac tatagaccct aaaatgcaag atgctttaga agaagaattt gatagaaata
    42601 gcaatttccc aggacatatg gtcggccctg atggagttag ccaaccacaa gctgcaatgg
    42661 taatcttaga ttataaaaat ggtgaaataa gagcactagc tggaggaaga aatataagtg
    42721 gtagaaaaac tttgaatcgt gctactaacc ctcatcagcc aggttcttct ataaaacctt
    42781 tagcaatata tacacctgct attgataccc taaaaataac acaatcaact gctctaagtg
    42841 attctcgagg aggatataag tttgaagaaa ataataaatg gaatccaaga actactactg
    42901 ctggtcatgg ttctatgagt ttacgtaaag cacttgctaa atcttcaaac acgatagctg
    42961 tcaaaactgc tgaaatgctt ggagactctt atgatgaatg tgtagatata atgatggatt
    43021 acttaaagaa ctttggtata acaactttaa agaataatca ctcaggttca tctgaagcaa
    43081 gtgatagaaa attcccatca ttgacactag gtggtatggc gaatggtatt actccacttc
    43141 aaatggctgc tgcttatggt acattggcaa atcaaggtgt ttatgtagaa ccttctattt
    43201 ttactactat aactaccttt gatggtcaat tattagttaa aaatgctcct gaagaacata
    43261 aagttgtaga ccctgaagta gcttatgttg ttacagatat gttagaaagc gtaattactg
    43321 aaggtactgg tggtgttgct acacttccaa agggaatgcc tgtagcaggt aaaacaggta
    43381 ctacaaatag tgcatatgat gcttggtttg tcggttacac tccttattat gttggtgcaa
    43441 cttatattgg agatgatgct ggtagaaaag atgattctgg taacactata aaacgtagag
    43501 aagtaccaca tggaagtact agtactgcaa aactatggga aaaaattatg gaaaaaatac
    43561 atgctaattt aacggttact gaatttgaag ttcctaaaaa tgtatatttt acaaaaatta
    43621 atttagagga tggaggaaag caatcttctg gctctaaagc agcatttatt gaaggtactg
    43681 ctcctactaa agtaagttct caaccatcat ctgaagatac aaaaaaacca gacaataacc
    43741 aaccagaaga aaataataat aacaataata acacaggtga taatggtggc ggttctactc
    43801 ctcctgataa tggcggaaac aatggtggtg gctc
//
LOCUS       DAMJYN010000262        20758 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.guided.068, whole genome shotgun sequence.
ACCESSION   DAMJYN010000262 DAMJYN010000000
VERSION     DAMJYN010000262.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20758)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20758)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20758
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.guided.068"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            190..1788
                     /locus_tag="PC466_003877"
     CDS             190..1788
                     /locus_tag="PC466_003877"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative manganese-dependent inorganic
                     diphosphatase"
                     /protein_id="HDF2771180.1"
                     /translation="MSLLVFGHKNPDTDSICSAISLAHLKNKLGIKATAYALGDIRKE
                     AKYALDYFKVDAPEILDNVRIQVRDLNYDKVVPLTPTSSILEAYNLMDEKNVKTLPVT
                     YDDGTFAGIITMKEIAKNLLHQHFTTIHTSLSNICKNLNGTILVDCGEDIKGRVVTLS
                     FGMETLIETLKEGDIAIVGDRYDSIEYAIDTKVKLLILTNHTEISKDLLALAKINGVS
                     VVSVESDNYKTSNVINQCSFLDSIEATENLITFKEDDYMDEIKEIMLETNFRSYPILD
                     DDNKFLGLVSKGHLLNPSKKNVVLVDHNEYAQSADGIEQANIVEIIDHHKLGGISTDV
                     PMSFRVMPVGCNSTIIYQMYKENNVEIPYEIAGLLLSAILSDTLLFKSPTTTDMDKKA
                     CEELSKIAKVDMEKYAMDMFKCGTSLDEYTIEEIVNMDFKEFNMSGHRVGIGQVFTLD
                     IDSIFAKKDEFLSYINSTDYDKLILAVTDIIKEGSYLIYKAEDSLIANAFDVEGVQGT
                     FAPGVVSRKKQLVPNLTTAIKNFK"
     gene            complement(2023..2214)
                     /locus_tag="PC466_003878"
     CDS             complement(2023..2214)
                     /locus_tag="PC466_003878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exosporium protein"
                     /protein_id="HDF2771181.1"
                     /translation="MAGLTTEPGGGGVLSGYFAGFLFGGTTFTINNFSSTTVGIRNGQ
                     SAGTAATLTIFRIADTVMT"
     gene            complement(2383..2976)
                     /locus_tag="PC466_003879"
     CDS             complement(2383..2976)
                     /locus_tag="PC466_003879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like protein"
                     /protein_id="HDF2771182.1"
                     /translation="MRIPDILKDKSILKAELFIHIDSNKNHIFKEKVDIEIKRISEYY
                     NLRTITWNDRVSMENIRGYLPIGISDTSNYICLNITGTIKAWAMNKYPNYGLALSLNY
                     PYQIFEFTSSRDCNKPYILVTFEDRIIDNCYPKCECLPIRITGPMGPRGATGSIGPMG
                     ATGPTGATGNSSQPIANFLVNAPSPQTLNNGNAITGW"
     gene            complement(2977..3123)
                     /locus_tag="PC466_003880"
     CDS             complement(2977..3123)
                     /locus_tag="PC466_003880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exosporium protein"
                     /protein_id="HDF2771183.1"
                     /translation="MRKIILYLNDDTFISKKYPDKNFSNLDYCLIGSKCSNSFVKEKL
                     ITFF"
     gene            complement(3801..4325)
                     /locus_tag="PC466_003881"
     CDS             complement(3801..4325)
                     /locus_tag="PC466_003881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HDF2771184.1"
                     /translation="MENKNPIVTIEMENGKEIKIELYPNIAPNTVKNFVSLVNEGYYN
                     GIIFHRVIPGFMIQGGCPNGTGMGGPGHSIKGEFSGNGFTNNLKHERGVISMARTMAP
                     NSAGSQFFIMHKNSPHLDGQYAGFGRVIEGMDTVDEIASVRTDSADKPQTPQIMKSVT
                     VETFGIDYSDVEKN"
     gene            complement(4390..5142)
                     /locus_tag="PC466_003882"
     CDS             complement(4390..5142)
                     /locus_tag="PC466_003882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HDF2771185.1"
                     /translation="MKLGLCLEGGGAKGAYQAGVVKALYDGGINKFYSISGTSIGAIN
                     GYYLYTGNVDNLEKMWTNIKDIQNGNVKIVNNTVDNSPAIDNLRELDDSNIEEMNFYV
                     NYVEVDNKVVSEKIVDISKMPRNEAIISISYSGLLPSNPNATLGFKEQFVKDVQEGIY
                     DGFKLDGGLIRSALIEPLIGDNVDKIILISTKYNYELPEDIKKVYDEDKIIVVRPNTQ
                     FAPKDTLNFDDEFCKTIYQEGYEIGKNILDRL"
     gene            complement(5173..6471)
                     /locus_tag="PC466_003883"
     CDS             complement(5173..6471)
                     /locus_tag="PC466_003883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M18 family aminopeptidase"
                     /protein_id="HDF2771186.1"
                     /translation="MDSINFAKNLIDFIYDSPSSFHAVESTKEILDKNGFEELVLNQR
                     WNLRVGGKYYVTKNLSAIVAFVVNSEDIERDGFRIIGSHSDSPTFSIKPNAEIEAEKS
                     YLKLNTECYGGAILSTWLDRPLGIAGRVVLKGDSILKPNERLIDFKKPICIIPNLAIH
                     LNRSINDGHSYNKQKDMLPLVGMLNDTLEKDNFLIKQIASNLDVNMEDIIDFDLFLYE
                     FEKGSLIGANDEFISIGRQDNLAMVHASLNALVNTKGQQGVNVMAVFDNEEVGSSTKQ
                     GADSNMLLNILERICISMGKDREGFFESIYSSFMISSDLAHAIHPNIPEKHDPTNKPI
                     MGKGPVIKINASQAYTSDGYSIAIYKNICREVNVEYQEFVNRSDERGGSTIGPISSTH
                     IDIPSVDVGSPILAMHSIRELGNVEDHYSIYKTFSKFFEI"
     gene            complement(6488..8752)
                     /locus_tag="PC466_003884"
     CDS             complement(6488..8752)
                     /locus_tag="PC466_003884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3553 domain-containing protein"
                     /protein_id="HDF2771187.1"
                     /translation="MNLDTLNPAQREAVEKTEGPVLILAGAGSGKTKVLTTRIAYLIE
                     DKGVQAPNILAITFTNKAANEMRERVEQNIGPETKDMWISTFHSCCVRILRKDINKIG
                     YNRSFVIYDSADQVTLVKDCLKELNLSDKVFEPKAVISAISGAKDKLYTPKQFKDINM
                     ADNRMVKIADIYALYQDRLKRNSALDFDDLILKTVELFKANDEVLAYYRSRFRYIMVD
                     EYQDTSKAQYELIKLLAREHQNICVVGDDDQSIYGWRGADIRNILEFEKDYDNVHVVK
                     LEQNYRSTQVILDAANKVISNNIERKRKKLWSEKKEGELIKIQLTGSEIEEADFIADS
                     IAQIARKENRPYKDFAVLYRANAQARPVEDALNRSQIPYNIYGGTKFYERKEIKDLLA
                     YLRVIQNPQDDISIKRIINVPRRGIGLRTIEKIEDRANLKQESIYSVLIDIETNSDIS
                     TKARASISGFVDIIGTLRTIKEVYPVSKLIEKVLDTTGYMDELVEIRNKNEKDLTGKG
                     EEAQDRIDNLREFISIALEFESSNDDTYENKDLETFLTSIALTSESNDEEDNDRVSLM
                     TIHTSKGLEFPVVFLTGMEEGLFPISRAIKSMSDSQIEEERRLCYVGITRAKEELYMS
                     LTEKRTLYGKTNVAIASRFMEELPEECIERLYKVKKELSYSKASYNMLDKYTKKYMST
                     ISKSKVADKVNATIKDSNKETNPDDIKLGSKVHHPKFGVGTVVSIIGTDVTIAFDQQG
                     IKKINKEYTTLNIL"
     gene            complement(9007..9825)
                     /locus_tag="PC466_003885"
     CDS             complement(9007..9825)
                     /locus_tag="PC466_003885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HDF2771188.1"
                     /translation="MFKINNLTYQYEKNTNALLNINMDFSKGNVIGIIGSNGSGKSTL
                     FMNLMGILKPTSGEILFKEEKLKYDKRSLYNLRKNVGIVFQDPEKQIFYSKVYDDIAF
                     AMRNIGIDEKIIKERINKALVAVNGIDFIDRPVHFLSYGQKKRVAIASVIAMENEIIL
                     LDEPTAGLDPVSTRSIVDIIKGLNKDNIKIVISSHDMNLMYEICDYIYVLDKGILIDE
                     GKAENVFVNENNIIQAGLESPWLVKVHRNMNLPLFKKEEDLYKYWKERELNTNK"
     gene            complement(9818..10516)
                     /gene="cbiQ"
                     /locus_tag="PC466_003886"
     CDS             complement(9818..10516)
                     /gene="cbiQ"
                     /locus_tag="PC466_003886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ECF transporter T component CbiQ"
                     /protein_id="HDF2771189.1"
                     /translation="MLIIDKYAYTNRLSKVNPNKKVAIGVIFLIASMVIKNIFVLSGI
                     MILMSILVVCVAGIDLKNYLKLLRIPMYFLFLSIGITLVNISFNKADLLYSFEIFSFN
                     VGISKASIDMSIHVLFRAMSCLTCVYFCILTTPFNQLIFFFKKMHLPDTFVELSMLIY
                     RFIFIFLEEFSEIYKSQELRFGYINLKTSYKSLGILGSMLYKRLMTRYDDMCISLDIK
                     LYDGKFHIVGDNDV"
     gene            complement(10519..10803)
                     /locus_tag="PC466_003887"
     CDS             complement(10519..10803)
                     /locus_tag="PC466_003887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     substrate-binding protein"
                     /protein_id="HDF2771190.1"
                     /translation="MSAKTKTKTNILLLLLVVALIIFPLLVNSGAEYGGADGQAESEI
                     TKINPDYEPWFSSPYEPPSGEIESLLFSAQAALGAGVIGYILGVQKGKRS"
     gene            complement(10793..11545)
                     /locus_tag="PC466_003888"
     CDS             complement(10793..11545)
                     /locus_tag="PC466_003888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006440549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter permease"
                     /protein_id="HDF2771191.1"
                     /translation="MKQNIKLGVIAALMLIVLTPVTSNAMHIMEGYLPVKWSIAWGVI
                     FIPFFLVGLKSIGKIVKQDPKKKVLLALCGAFVFVLSALKIPSVTGSCSHPTGVGLGA
                     IMFGPSVMFVLGTIVLIFQALLLAHGGITTLGANAFSMAIIGPIISFLIFKALKKKDG
                     NNAMPVFLAAAIGDLATYTVTSIQLALAFPDPSGGVMASAIKFLGIFFMTQIPIAIAE
                     GILTVIVYNLITENGEKSILENNDKGVKANEC"
     regulatory      complement(11734..11926)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            complement(12058..13830)
                     /locus_tag="PC466_003889"
     CDS             complement(12058..13830)
                     /locus_tag="PC466_003889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitric oxide reductase activation-like protein"
                     /protein_id="HDF2771192.1"
                     /translation="MKWIYDDYEFENRANNLSWTIAGDYNESIDISEKDYSSKEIGLY
                     FAIIAGARRKYVDWDIVKKYLTNRIRKGYNKDIILGLIQVILNTIVEEKVIKDRPGIE
                     DIRRNAYKDIVSRFTKIHNDNIMDKIKYTFVLYNMDKHPALDSMTRRIVNDIRNIDTN
                     QDMMEILKALDVIYLTYFEYILNGEENSLIDENNVESVEVNFDTFADFMYEELYSDEE
                     ENIIESDIDSISSSMLVEGVGDFDDSKCSNSADRVIYVDEDTANKIYSKIEHYYGKTY
                     LSKGEIKKIETQNCRNVHEGCRIHFTDGVLRSECNNVFQLKYVTRQKENNLGKFREHA
                     RMYRQQIKRLKESLSRILIEENAKSRVYSDCGTILANRAWRVGRSNNNKIFYKDIENE
                     KGKYVIDILLDASGSQSRNQGNVAIQAYIIANALTEVGIPNRVMGFSSFLDYTILKRF
                     KDYDDSIKNSENIFEYFCAGNNRDGLAIKSICSGLINRDEENKILIVLSDGRPNDVKI
                     GKSSERTLRGEKAYRGIVGLRDTANEVRKARKQNILVLGVFTGKESELEAERLIYGND
                     FIYSRDITRFSDVVSMYLKKIIRN"
     gene            complement(13844..14773)
                     /locus_tag="PC466_003890"
     CDS             complement(13844..14773)
                     /locus_tag="PC466_003890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF2771193.1"
                     /translation="MDIIDNLRVQGVDEKLIEDVLYFRNYYGLEKDLEYRVTKSKTYF
                     YGKDILSMCIAAILEEENILLSGPKATGKNLLADNLGEIFNRPQWNTSFHINTDSSTL
                     IGTDTFIDNEVKLRRGSVYECAINGGFGVFDEINMAKNDAIVVVHSALDYRRIIDVPG
                     YERVNLHPATRFIGTMNYEYAGTKELNEALVSRFMVIDIPPIEEDKLMMILKNEFSDA
                     DEEKLIHFAGIFLDLQLKSQNGEISSKAIDLRGLMASLKTIRRGLKPTLAINMGLTGK
                     TFDVYEKEMVGDVIKTRIPNKWESIDVFPISHI"
     gene            15002..15190
                     /locus_tag="PC466_003891"
     CDS             15002..15190
                     /locus_tag="PC466_003891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2771194.1"
                     /translation="MEYMSCPEVAKKWGISERRVQKLCEESRIPGVSKLGYMWLIPKN
                     AEKPVDGRAKRRKEVQYE"
     gene            15183..15884
                     /locus_tag="PC466_003892"
     CDS             15183..15884
                     /locus_tag="PC466_003892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2771195.1"
                     /translation="MNSVLIIDDDKELCALMKKCVEQENLSAITAHCGAEGLHLLDKN
                     RHTLSLVILDIMMPDIDGFQVLKKIRETSNIPVIMLTAKNDEDDKVSGLRLGADDYLT
                     KPFSINELMARVNSLIRRYTMLNPAFITDTDCIIINGMIIDKTNRIVSINNIPVQLTS
                     KEFDLLAFLASNKGRVFTKKQIYTQVWEEEYAFDDSNIMSFISKLRKKIEPDPNHPFY
                     ILTVRGVGYRFNKEA"
     gene            15886..16809
                     /locus_tag="PC466_003893"
     CDS             15886..16809
                     /locus_tag="PC466_003893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2771196.1"
                     /translation="MNTSVYLLLILALSLIIIAYLVSVLLRVRIQLTLIKDALEDIKN
                     GNLNRRILTDENDITKQICYDINEIAINSQFQLIQQKQSEQAYKQLMTSLSHDVKTPL
                     ASLVGYLEAVESKIVVGEEKDEYIHVASNKAHYLKNFVENLFEWVKLDSKEQVFHFDI
                     FDLNELSRNIISDWIPVLESSHFEYEFDIPEIEYFLRIDANAYTRIINNLLQNIITHS
                     SGNKMTLRIFENKEQAQIIITDNGKGISSDNLPHIFERLYQCDHSRASKGNGLGLAIA
                     KELINAHKGNITANSTPGMGTEFTILLPKAL"
     gene            16966..17889
                     /locus_tag="PC466_003894"
     CDS             16966..17889
                     /locus_tag="PC466_003894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019639192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2771197.1"
                     /translation="MNDFVIETKQLTKIYGNQTVVDKVNLHVKKGRIYGLLGRNGAGK
                     TTIMKMILGLTSITYGEVDVFGENIKGCEKRVYPRIGAIIETPGFYPNLTGTENLEIF
                     AKLRGTAAPNSVKRALEIVGLPYKNKKLFSKYSLGMKQRLGIANAILHDPELLVLDEP
                     TNGLDPIGIAEMRKFIRDLSVEHGKTILISSHILSEISLLADDIGIIDHGVLLEESSM
                     SELEKKNSKYILLQVSDIPKTSLILERQFNTKDYSVQDDHTLRLYNTTLDMGEINKAL
                     VMQNVTVISSQLCNDTLEDYFKKITGGEGIA"
     gene            17882..18619
                     /locus_tag="PC466_003895"
     CDS             17882..18619
                     /locus_tag="PC466_003895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2771198.1"
                     /translation="MLKLIQTEFLKLRRRKLIWLMLLSALIMPFFALLYFNYFGKTGV
                     EPTKFYKWSAFGYTLWIILPVVLGIFCTMLIHEENQYDMLKQLWIVPISKMGYFFSKF
                     FVVLIYSICFMLITAVASVLFSVLSGYVVFSWASILYLLKKCLEIGVITAFVMLPILA
                     IATSQKGYILPICITLVYAFSGFVIMTINMYLHPLSSMGVIIMRNKDIPGLIFSQEIN
                     VPLAFLCICIWSIVSVLFASIALGRRK"
     gene            18630..19403
                     /locus_tag="PC466_003896"
     CDS             18630..19403
                     /locus_tag="PC466_003896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2771199.1"
                     /translation="MWKLLWAECQKIRRSKIVWITFFASIMIAVIVFAGGQDVYNDPD
                     LHYGLKSVYDGSRYIDNAGWYMDAVQPWSTFFVLPAVIALLGSYIICREEEEDTIKSL
                     RLIPINETKLTIAKMIITFIFSILLYLLLFTITFLTESVLHFSDLSTKLVLSCMKEYF
                     LDGIGVFFAISPIIALVSRMKKGYWLALVFTEVYSIAGLFAGMSNVLQTFFPIAAIFN
                     ISGYYITTGEKIMGSIISLLLCACLSAFILKGLKHNEKN"
     gene            complement(19944..20552)
                     /locus_tag="PC466_003897"
     CDS             complement(19944..20552)
                     /locus_tag="PC466_003897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HDF2771200.1"
                     /translation="MSVINSFILQYGLISVFVLIMIEYACFPLPSEVVLPLCGAIAAR
                     NHFGFLTILILSIIAGILGSIFCYTVGNWGGKSIINKIIEICPKAKKGIFASQDYFNK
                     YSSISVCVCRLIPLCRTYISFIAGIAGQNIITFVISSIVGITIWNTSLISIGYIFSES
                     WVRIMSHYNDYKFLVLIIPISIIFIGFVIKSFIHKKHHKIRL"
BASE COUNT         6840 a         3471 c         2632 g         7815 t
ORIGIN      
        1 atgtttggtt gggtaaaaat atatataata ataattttta tattaaattt gtagtattta
       61 tgtaagaaat aaattttata taatattttt tcactaaatt tttttctttt tacaacaaat
      121 actcactacc ttttgatata atatttttat caattattat tatattcaag ttttgaaagg
      181 agtattaaaa tgagtttatt agttttcgga cataaaaatc cagatacaga ttcaatatgt
      241 tctgcaattt cattagcaca tttaaagaac aaactaggaa taaaagcaac agcttatgct
      301 ttaggagata tcagaaaaga agctaaatat gccttggatt actttaaggt agatgcacct
      361 gaaattttag ataatgttag aatacaagtt agagatttaa attatgataa agtagtacct
      421 ttaacaccaa cttcatctat attagaggct tataacctta tggatgaaaa aaatgttaaa
      481 acactacctg taacttatga tgatggaact tttgctggta tcattactat gaaagaaata
      541 gctaaaaatc tacttcatca acactttaca actatacaca catcactatc aaacatttgt
      601 aaaaacctta atggtactat tcttgtggac tgtggtgaag atataaaagg tagagtagtc
      661 actttatcat ttggaatgga gactctaata gagactttaa aagaaggaga catagctatt
      721 gttggagata gatatgatag tattgaatat gctattgata caaaagttaa acttttaata
      781 cttactaatc atacagagat ttcaaaagat ttgctagctc ttgctaagat aaatggagtg
      841 tctgttgttt ctgttgaaag tgacaattat aaaacttcta atgtaataaa tcaatgtagt
      901 ttcttagact ctatagaagc tacagaaaat ttaattacat tcaaagaaga tgattatatg
      961 gatgaaataa aagagattat gctagaaaca aacttcagat cttatccaat attagatgat
     1021 gataataagt ttttaggttt agtttcaaaa ggtcatctat taaacccatc taaaaagaat
     1081 gttgttttag ttgaccataa cgaatatgct caaagtgctg atggaattga acaagcaaac
     1141 atagttgaaa taattgacca tcataaactt ggtggtattt ctactgatgt tcctatgtca
     1201 tttagagtta tgcctgttgg atgcaatagt actataattt atcaaatgta caaagaaaac
     1261 aatgttgaga taccttatga aatagctggg cttcttttat ctgctatatt atcagataca
     1321 ttattattta agtctccaac aacaactgat atggataaga aagcttgtga agaattaagt
     1381 aaaatagcaa aagtagacat ggaaaaatac gctatggata tgtttaaatg cggtacttct
     1441 ttagatgaat atactataga agaaatagta aatatggatt ttaaagaatt taatatgagt
     1501 ggacatagag ttggtattgg acaagtattt accttagaca tagactctat atttgctaaa
     1561 aaagatgagt ttttatctta tataaattcg actgattatg acaaactaat tcttgcggtt
     1621 acagatataa tcaaagaagg ttcttattta atctataaag cagaagatag cttaattgct
     1681 aacgcatttg atgttgaagg tgttcaaggt acatttgcac caggtgttgt atcaagaaaa
     1741 aaacaattag tccctaattt aactactgca atcaaaaatt ttaaataata taaaattttt
     1801 aaataacgaa aactgtctca aatctatatt tgagacagtt ttttattata catatattga
     1861 taataaagtt aaataaaaat ccataaattt aaaattttta tgaatatatt ttattattat
     1921 tgttatttta ttcattctaa aataggtaaa actcaatata taaaaatact tttgtcattt
     1981 aaataaaacc taaatagttt ttaagattat tttagacacg ttttaagtca taacagtatc
     2041 agctattcta aatatcgtca aagtagccgc agttcctgct gattgcccat ttcgtatccc
     2101 tactgttgta gatgaaaaat tatttattgt aaaagtagtc cccccaaata aaaaaccagc
     2161 aaaatatcca gaaagtactc ctccgcctcc tggctcagta gtaagccctg ccaaatcttt
     2221 tcctcctaaa attgggaata ggatagcaaa agaatattga tttatacttg atgaacctgg
     2281 ttgtaatgct actgaaactg atatataata cacaccattt tcttgtactg taaacgtacc
     2341 atttgcatct actgttatac ttgaactatt tcctattatt gtttaccaac ctgttatagc
     2401 atttccatta tttagtgttt gtggagatgg tgcatttacg aggaagttag caattggctg
     2461 agaggaattg cctgttgctc ctgttggacc tgttgctccc attggtccta tacttcctgt
     2521 cgctcctctt ggtcccattg gacctgtaat tctaattgga agacactcac atttaggata
     2581 acaattatct ataattctat cttcaaatgt tacaagtata tacggtttgt tacaatccct
     2641 actagatgta aattcaaaaa tctgataagg gtaatttaaa gataaagcta acccataatt
     2701 aggatattta ttcattgccc atgcttttat agttcccgta atatttaaac aaatatagtt
     2761 ggatgtatca cttatcccaa ttggtaaata tcccctgata ttttccatag acactctatc
     2821 attccatgtt atagttcgta aattataata ttcacttatt cttttaattt caatatctac
     2881 tttttcttta aaaatatgat tcttatttga atcaatatga ataaataact ctgcttttaa
     2941 tatacttttg tcttttaata tatctggtat tctcacttaa aaaaaagtaa tcaacttttc
     3001 ttttacaaaa ctatttgaac atttacttcc tattaagcaa taatctaaat tactaaagtt
     3061 tttatctgga tattttttag atataaaagt atcatcattt aaataaagta taatttttct
     3121 catttataat ccctccattt tgggtctata tcatactatg tttaaaatac atgcttagtt
     3181 acaatacaat taaaatttat agtattaaat ttttatataa taatgctgat ttctacaaaa
     3241 aaagaacatg tcattagaaa cttctaatag catgttcttt ttcattatta tatattacac
     3301 tttaaattat tccttgactg gcttagctgg tgtaaactaa accagtcttt ctaaaatatt
     3361 aagcactttt ttcttattat gttttttagg atttattgtc tctattattg taaaccaaag
     3421 ttataaaatt gtaaatagaa tatattacca taacaatatt tttttataag taaaaattat
     3481 aaaaaacctt atttttatta aatagaataa ataaaataag tttaaaaaat actgaaataa
     3541 gtgttttcca catattttat atatttattt aatacattat tatttaaaaa taaatatata
     3601 aacaatcata ataaaatttt tttaataaaa ctttattttt tagttaaaat catacaatat
     3661 atagctttcc acaatacaaa taaattaaaa agtgaaatgt atttgtctaa aaacataata
     3721 acatttcact ttatcctcat ttttaagtaa tatatatttt taatttttat ttataactca
     3781 atctagtttt tatataagtt ttagtttttt tctacatctg agtaatctat tccaaaagtt
     3841 tctacagtaa cagacttcat aatttgtgga gtttgtggct tatcagctga atctgttcta
     3901 actgatgcta tttcatcaac tgtatccata ccttctatca ctctaccaaa acctgcatac
     3961 tgaccatcta agtgtggtga gtttttatgc attatgaaaa attgagaacc agctgaatta
     4021 ggtgccatag ttctagccat tgatatgact cctctttcat gttttaaatt gttagtaaat
     4081 ccattaccac taaattcacc ttttattgag tgacctgggc cacccattcc tgtaccattt
     4141 gggcatcctc cttgtatcat aaatcctggt attactctat gaaatattat tccattgtaa
     4201 tatccttcat ttactaatga tacaaagttt ttaactgtat ttggagctat atttggatat
     4261 aactcaattt tgatttcttt tccattttcc atttctatag ttactatagg atttttattt
     4321 tccataattt attaccttcc ttttcattag ttaaattaca taattacatt tattatatta
     4381 tactctaaat taaagtctat caagtatatt ttttcctatt tcgtatcctt cttgataaat
     4441 agttttacaa aactcatcat caaagttaag cgtatcttta ggagcaaatt gagtattagg
     4501 tctaactact attattttat cttcatcata tactttttta atatcctctg gcaactcata
     4561 attatatttt gtggatatta aaataatttt atccacatta tccccaatta atggttcaat
     4621 taatgcactc ctaattaaac ctccatctaa tttgaaacca tcataaattc cttcttgcac
     4681 atctttcaca aattgttctt taaatccaag agttgcgttt ggatttgatg gtaacaaccc
     4741 actgtatgaa atgctgataa tggcttcatt acgaggcatt tttgatatgt caacaatctt
     4801 ttctgatact actttattat caacttcaac ataattaaca taaaagttca tttcttctat
     4861 attactatca tctagttccc ttaggttgtc tatagcagga gaattatcca cagtattatt
     4921 tactattttt acatttccat tctggatatc ttttatattt gtccacattt tctccaagtt
     4981 atcaacattc cctgtgtaca aataatatcc atttattgct cctattgatg tccctgaaat
     5041 cgaataaaat ttatttattc ctccatcata caaggcttta actactcctg cttgataagc
     5101 cccttttgct cctccacctt ctaaacataa tcctaatttc atagtctcat ctccaaattg
     5161 tttatcttat atttatattt caaaaaactt actaaatgtt ttatatatac tatagtggtc
     5221 ctcaacattt cctaattctc ttatagagtg cattgctaaa attggacttc ccacatccac
     5281 agatggtata tctatatgag tagaagatat tggacctata gtacttcctc ctctttcatc
     5341 tgacctatta acaaattctt gatactcaac attaacttct ctacatatat ttttataaat
     5401 agctatagaa tatccatcac tagtatatgc ctgactagca tttatcttta taactggacc
     5461 ttttcccatt attggtttat tagttgggtc atgcttttct ggaatgtttg gatgaatagc
     5521 atgagctaaa tctgatgata tcataaaaga tgaataaata gactcaaaga atccctctct
     5581 atccttaccc attgatatgc aaattctctc caatatattt aacaacatgt ttgaatctgc
     5641 accttgttta gtagagctac caacttcttc attgtcaaat acagccatta catttacacc
     5701 ttgttgacct ttagtattaa caagagcatt caaactagca tgtaccattg caagattatc
     5761 ttgtctccca atagatataa attcatcatt agcccctatt aaacttcctt tttcaaattc
     5821 atataaaaat aaatcaaaat ctataatatc ttccatattt acatctaagt tagatgctat
     5881 ttgctttata agaaaattat ctttttctaa tgtatcattt aacatcccaa ctaaaggtaa
     5941 catatctttt tgcttattat atgaatgacc atcatttata cttctattta aatgtattgc
     6001 tagatttggt attatacaaa ttggcttttt aaagtctata agcctttcat ttggttttaa
     6061 tatactatca ccttttaaaa ctactctacc agctatccca agaggtctat ccaaccatgt
     6121 acttaatatt gctcctccat agcattctgt atttaacttc aaataagatt tttcagcttc
     6181 tatttctgca tttggtttaa tactaaatgt aggagaatct gaatgagagc ctattattct
     6241 aaatccatct ctttctatat cttctgaatt tactacaaaa gctactatag ctgatagatt
     6301 cttagtaaca taatactttc caccaactct tagattccat ctttgattca aaactaattc
     6361 ttcaaatcca tttttatcta agatttcctt agtactctcg actgcatgaa aagacgacgg
     6421 actatcatat atgaagtcta ttaagttttt agcaaagttt atactatcca ttcctcattt
     6481 acctccatta taaaatattt agtgttgtat attctttatt tattttttta attccctgtt
     6541 ggtcaaaagc tatagtaaca tctgtaccaa ttatagaaac cactgtccca accccaaatt
     6601 taggatgatg taccttagaa ccaagtttta tatcatctgg attagtttct ttattagaat
     6661 cttttattgt agcattaact ttatctgcaa ctttagattt gcttatagta ctcatatact
     6721 ttttagtata tttatctaac atattataac ttgctttaga atagcttagt tcttttttta
     6781 ctttgtacaa tctttctata cattcttctg gcagttcttc cataaatctt gaagctattg
     6841 caacatttgt tttaccatat aatgttctct tctctgtcaa tgacatatat agctcttctt
     6901 tagctctagt tataccaaca taacaaagtc ttctctcttc ttctatttgt gaatcactca
     6961 tagattttat agctcttgat ataggaaata acccttcttc catacctgtt aaaaacacaa
     7021 cagggaactc taaacctttg gatgtatgaa ttgtcataag cgaaacccta tcattgtctt
     7081 cttcatcatt tgattcagat gtaagtgcta tacttgttag gaatgtctct aagtctttat
     7141 tttcataagt atcatcatta ctactttcaa actccaaagc tatagaaata aattctctca
     7201 aattatcaat tctgtcttga gcttcttcac ctttgcctgt taaatctttt tcatttttat
     7261 ttcttatctc tacaagctcg tccatatatc ctgtagtatc caagactttt tctataagtt
     7321 tgctaacagg ataaacttct tttatagttc taagagtccc tataatatca acaaatccac
     7381 ttatacttgc ccttgcctta gtagatatat ctgaatttgt ttctatatca attaatactg
     7441 agtatatact ttcctgtttt aagttagctc tatcttcaat tttttctata gttctaagcc
     7501 ctatacctct tctaggaaca tttataatcc tttttataga tatatcatct tgtggatttt
     7561 gaataactct taaatacgcc aacaaatcct ttatttcttt tctctcgtag aattttgtac
     7621 caccatatat attgtatgga atttgacttc tatttaaagc gtcctctaca ggtcttgcct
     7681 gtgcatttgc tctataaagt actgcaaaat ccttataagg tctattttct tttctagcta
     7741 tttgtgcaat tgaatcagca atgaaatcag cctcttctat ttcgctacca gttaattgta
     7801 tctttataag ttctccttct tttttttcac tccaaagctt ttttcttttt ctttctatat
     7861 tattagatat aactttatta gctgcatcta atatcacttg tgtagaccta taattttgtt
     7921 ctaactttac aacatgtaca ttgtcataat ctttctcaaa ttcaagtatg tttcttatat
     7981 ctgcgcctct ccatccataa atactttggt catcatctcc aacaacacaa atattttgat
     8041 gttctcttgc taataatttt atcaattcat attgagcttt acttgtatct tggtactcat
     8101 ctaccattat gtatctaaat ctacttctgt aatatgctaa tacttcatca ttagccttga
     8161 aaagttctac agttttaagt attaaatcat caaagtcaag tgcactattt ctttttaaac
     8221 ggtcttgata taacgcataa atatctgcaa tcttaaccat tctattatct gccatgttga
     8281 tatctttaaa ctgctttgga gtataaagtt tgtcttttgc tcctgaaatt gcacttataa
     8341 ctgcttttgg ttcaaacact ttatcactta aatttaattc ttttagacag tctttaacca
     8401 atgtaacttg gtctgctgaa tcataaatta caaaacttct attgtaacca atcttattta
     8461 tatcttttct tagtatacga acacagcaag aatggaatgt acttatccac atatccttag
     8521 tttcaggacc tatattttgt tcaactctct ctctcatttc atttgcagct ttgtttgtaa
     8581 atgttatagc taatatattt ggtgcttgta cacctttatc ttctataaga tatgctattc
     8641 ttgttgttaa taccttagtt ttacctgaac cagcaccagc cagtataagt actggacctt
     8701 cagtcttttc tactgcttct ctttgagcag gatttaatgt atctaaattc atatttctcc
     8761 tcctgttaac agccataaat atattttaat ctaaaatatg aattacttca aattataatt
     8821 atgtattata ttaatagatt atttccaata tattacaatt aaataacatt tttccatata
     8881 atttatttaa ttgtttaata aaaaaaataa ccttatgatt tggggaatca taaggcacct
     8941 ttaaggggtc taggttaagg gttattatat ataaatctat ttttttaaaa taggtttagg
     9001 gcttaattat ttatttgtat taagttctct ttccttccaa tacttataca aatcttcttc
     9061 tttcttaaat aagggtaaat tcatatttct atgtactttt actaaccatg gggattctag
     9121 gccagcttgt ataatgttat tttcatttac aaatacattt tctgcctttc cttcatcaat
     9181 taaaatcccc ttatccaata catatatata atcgcatatt tcatacatta aattcatatc
     9241 atgactggat attactattt ttatattatc tttattcaat ccctttatta tatctacaat
     9301 agacctagta cttactgggt ctaaaccagc tgtaggctca tcaagcaata taatttcatt
     9361 ttccattgct ataactgatg ctatcgctac cctttttttc tgaccataac ttaaaaaatg
     9421 tactggtcta tctataaaat ctattccatt aacagctact agagctttgt ttattctctc
     9481 tttaattatt ttttcatcta taccaatatt tctcattgca aaggctatat catcatatac
     9541 ttttgaataa aaaatttgtt tttctgggtc ttggaacaca atacctacat tttttctaag
     9601 gttgtataaa cttctcttat catattttaa cttttcttct ttaaaaagaa tttctccaga
     9661 tgtaggcttt aatataccca ttaaattcat aaataatgtt gattttcctg aaccatttga
     9721 acctattata cctataacat ttccctttga aaaatccata ttaatattta atagtgcatt
     9781 ggtattcttt tcatattgat aagttaaatt atttatttta aacatcatta tcccctacta
     9841 tgtgaaattt accatcatac aattttatgt ctaatgatat acacatatca tcataccttg
     9901 tcataagtct tttgtacagc atactgccaa gaattcctaa tgatttatat gaagttttta
     9961 aatttatgta cccaaatctt agttcttgtg acttatatat ttctgaaaat tcttctaaaa
    10021 atatgaatat aaacctatat attaacattg atagctcaac aaaagtatca ggcaaatgca
    10081 tttttttaaa gaagaatatt aattgattaa aaggtgttgt aagtatacaa aagtatacac
    10141 aagtcaaaca agacatagct ctaaataaca catgaataga catgtcaata gatgcttttg
    10201 atattcctac attgaaacta aaaatttcaa aactatataa taagtctgcc ttattaaaag
    10261 atatatttac aagagttatt cctatactaa gaaataaaaa gtacattggt attctgagta
    10321 attttaaata attctttaaa tctattccag ctacacaaac aactagaata ctcattaaaa
    10381 tcataattcc acttaaaaca aatatatttt ttattaccat agaagcaatc agaaagatta
    10441 ctcctatggc tactttttta tttggattta ctttacttaa tctatttgta tatgcatatt
    10501 tatcaattat aagcataatt aacttctctt tcctttttga acacctaata tgtaccctat
    10561 tacaccagca cctaacgctg cttgtgcaga gaataataaa ctttctattt ctccacttgg
    10621 tggctcatat gggctactaa accatggttc ataatctgga tttatcttag taatttcact
    10681 ctcagcttga ccatctgctc ctccatattc agctcccgaa ttaacaagta atgggaatat
    10741 gataagagct actactaata aaagtagtaa tatattagtt ttcgtctttg ttttagcact
    10801 cattagcttt aactccttta tcattatttt ctagtatgct tttttctcca ttttctgtaa
    10861 ttaaattata tacaattaca gtaagaatac cctctgctat tgctattggt atttgagtca
    10921 taaagaaaat tcctaaaaac ttaattgctg aagccatcac tccacctgat gggtctggga
    10981 aagccagtgc taactgtatc gaagttactg tatatgtagc caaatctcct attgctgctg
    11041 caagaaatac tggcattgca ttatttccgt cttttttctt taatgcttta aatattaaga
    11101 atgatataat tggtcctata atagccattg aaaaagcatt agctcctaaa gtagttattc
    11161 ctccatgtgc caatagtaat gcttggaata ttagaactat agttccaaga acaaacatta
    11221 cacttggtcc aaacattatt gctccaagac ctactccagt aggatgtgaa caacttcctg
    11281 ttactgaagg tatctttagt gctgacaata caaatacaaa tgctccacac agcgctaata
    11341 atactttctt tttagggtct tgctttacta tttttcctat tgattttagt cctactaaaa
    11401 aaaatggtat aaatataact ccccatgcta tagaccattt tactggtaag tatccttcca
    11461 ttatgtgcat tgcattcgat gtaactggag ttaaaacgat taacataagt gcagctataa
    11521 cccctaattt gatattttgt ttcattttac tatcccctct ctccctttct aataattaaa
    11581 atataaataa tatatgtctg atttatttta aaaataaaaa taaaaaagcc taactcgatg
    11641 gctaggcttc taattttcga taatccaaat acaaacacat aaaatgaaca tatctgtata
    11701 attattataa gaaactttct ccatccccga agaaattact ttaatatttt aggcaggtct
    11761 cctgacttag cttcttccta ctcctcttcc ttcccatgag atataaaaaa tatcatcata
    11821 gtggctaaca aaagtttcgt ctgcatcaca gtagcggggg ctgtaaagga atttaacctt
    11881 tttccctatt aatcttgctt aaagaaccta taatattata tatttaattt ttaaattatt
    11941 cttaaatcat tttctatata aatcattgta taccttttct gtgaaaattt ctacattttt
    12001 tataaatttt attcattttt atatttttat gtatataaat tcttttttgt aagtttatta
    12061 atttctaatt atcttcttta aatacattga aactacatca gaaaatctag ttatatctct
    12121 tgaatatata aaatcatttc catatattaa tctttcagct tcaagttctg attcttttcc
    12181 tgtaaatact cctagtacta atatattttg ctttctagct tttctcactt cattggctgt
    12241 atctctcaaa ccaactatac ccctataagc cttttctcct cttaatgttc tctcactact
    12301 ttttcctatc tttacatcat ttggtcttcc atcgctgaga actatcagga ttttattttc
    12361 ttcatctcta tttattagac cactacatat agattttatt gccaaaccat ctctattatt
    12421 accagcacaa aaatattcaa atatattttc actatttttt atactatcat cataatcttt
    12481 aaatcttttt aatattgtat agtctaaaaa actagaaaat cccatcactc tatttggtat
    12541 gccaacttct gttagagcat ttgcaattat gtaagcttga attgccacat ttccctgatt
    12601 tctactttga gagccacttg catccaataa tatatcaata acgtatttcc ctttttcatt
    12661 ttctatatct ttataaaata ttttattatt attacttcta ccaactctcc aagctctatt
    12721 tgctaatata gtaccacaat cagaatatac tctactttta gcattttctt ctattaaaat
    12781 tcttgacaga ctttctttta atctctttat ttgctgtcta tacattctag catgttctct
    12841 aaattttcct aaattatttt ctttttgtct tgttacatat tttagttgaa atacattatt
    12901 acactcactt ctaagaactc catctgtaaa gtgtattcta caaccttcat gaacatttct
    12961 acaattttgt gtctcaattt ttttaatttc acctttactc aaataagttt ttccataata
    13021 atgttctatt tttgaatata tcttatttgc agtgtcttca tcaacatata taactcggtc
    13081 tgctgaattg ctacatttag aatcatcaaa atcccctaca ccttctacaa gcatggatga
    13141 agatattgaa tctatatcac tttcaataat attttcttct tcatcactat aaagttcttc
    13201 atacatgaaa tcagcaaatg tatcaaaatt tacttctaca ctttctacat tattttcatc
    13261 aataagacta ttttcttctc catttaatat gtattcgaaa taagttaaat atataacatc
    13321 taatgctttt aaaatctcca tcatatcttg attggtatct atatttctta tatcattaac
    13381 tattcttcta gtcatactat ctaatgctgg gtgcttgtcc atattataaa gtacaaatgt
    13441 gtatttaatt ttatccataa tattatcatt gtgtattttg gtaaaacgtg aaacaatatc
    13501 tttataagca tttcttctta tgtcttctat ccctggccta tctttaatga ccttttcttc
    13561 aactattgta tttaatataa cttgaattag acccagtata atatctttgt tgtatccttt
    13621 tcttattcta tttgtaagat attttttaac tatatcccaa tctacatact ttcttctagc
    13681 acctgcaatt attgcaaaat atagacctat ttcttttgaa gagtaatctt tttctgatat
    13741 atctatactt tcattgtaat caccagctat tgtccatgat aagttattag ctctattttc
    13801 aaattcataa tcatcatata tccatttcat aatctcacct atattaaata tgacttattg
    13861 gaaatacatc tatactctcc catttattag gtattctagt tttaattaca tctccaacca
    13921 tttctttctc atatacatca aaagtctttc ctgtaagtcc catattaatt gcaagagttg
    13981 gttttaatcc tcttcttata gtcttaagag atgccataag accacgtaaa tcaatagctt
    14041 tactagatat ctctccattt tgagacttca attgtaaatc taaaaatatt cctgcaaagt
    14101 gtattaattt ttcttcatca gcatctgaaa attcattttt taaaatcatc attaacttat
    14161 cttcttctat aggaggaata tctattacca taaatctaga taccagtgct tcattaagtt
    14221 cttttgttcc tgcatattca taattcatag tcccaataaa tcttgttgct ggatgtagat
    14281 tgactctctc atacccaggt acatcaatta ttcttctata gtctaaagct gaatgtacca
    14341 caactatagc atcatttttt gccatattaa tttcatcaaa tactccaaaa cctccattaa
    14401 tagcacactc ataaactgag cctcttctaa gtttaacttc attgtctata aatgtatctg
    14461 tacctataag tgttgaactg tctgtattta tatgaaatga tgtattccac tgaggtctat
    14521 taaatatttc ccctagatta tcagcaagta aattttttcc cgttgccttt ggtcccgata
    14581 ataatatatt ttcttcttct aaaatagctg ctatacacat agacaagata tctttaccat
    14641 aaaaataagt tttagacttt gttactctgt attctaaatc tttttctaaa ccataataat
    14701 ttctaaaata cagtacatct tcaataagtt tttcatctac cccttgcacc cttagattat
    14761 ctattatatc catattttta ccccttttat ataaatagta tttgtttcat ttcttatcac
    14821 cattttagca taaaaggata taagctaaaa ttgatttttt aatctccccc attttaagta
    14881 aaaccatgca ccattttatc actacaaaat taagagtact acttactgat atttcttgat
    14941 tttgttcgtc tatacgtata taatatatgc tgataaatta tgaggaaagg atgattgaaa
    15001 tatggaatat atgtcttgcc cagaagtagc aaaaaaatgg ggcatttctg aaagaagagt
    15061 acaaaaacta tgtgaagaaa gtcgcatacc aggagtttca aaactcgggt atatgtggct
    15121 gataccaaag aacgcagaaa agcctgttga tggtagagcg aaaagaagaa aggaagtaca
    15181 atatgaatag cgttttgatt atagatgatg acaaagaact ttgtgctctt atgaaaaaat
    15241 gtgttgagca agaaaattta tctgctatta ctgcacattg tggtgcagaa ggtctacatt
    15301 tgctcgataa aaatagacac acactctctc ttgtaatttt agacataatg atgccagata
    15361 tagacggttt tcaagttctg aaaaaaatta gagaaacaag taatattcca gtaattatgc
    15421 ttactgctaa aaatgacgag gatgataaag tttccggact acgtttaggt gctgacgatt
    15481 acctaacaaa accgttcagc ataaacgaac ttatggctcg tgtcaattct cttattcgtc
    15541 ggtatactat gttaaaccct gcttttataa cagacacaga ttgcataata ataaatggca
    15601 tgattattga caagacaaac cgaattgttt ctatcaataa tattcctgtt caacttacaa
    15661 gcaaagaatt tgatttactt gcttttctgg cttctaataa gggacgggta tttaccaaaa
    15721 aacagattta tacacaagta tgggaagaag aatatgcttt tgacgatagt aacatcatgt
    15781 ctttcatcag taaattgaga aaaaagattg aaccagaccc caaccatcca ttttatattt
    15841 tgacagttcg tggtgtcggt tatcgtttta ataaggaggc ttaacatgaa tacaagtgtc
    15901 tatctacttt tgatattggc tcttagcctg attattatag cgtaccttgt ttctgtcctg
    15961 ctacgtgtcc gaatacaact tacacttata aaagatgctt tagaggatat aaaaaatgga
    16021 aaccttaatc gccgtatttt aacagatgaa aacgacatta caaaacaaat ttgctatgat
    16081 attaacgaaa tagcaatcaa tagccaattt caacttattc agcaaaaaca atcagaacaa
    16141 gcctacaaac agctaatgac aagtctctcc catgatgtaa aaactccact tgcttctttg
    16201 gtcggttatt tggaagcagt agaaagtaaa attgttgtag gagaggaaaa agacgagtat
    16261 atccatgttg cgtctaataa ggctcattac ttaaagaatt ttgtagaaaa tctatttgaa
    16321 tgggtaaaat tggattctaa ggaacaagtt tttcattttg atatttttga cttgaatgaa
    16381 ttatcccgta atattatatc tgattggata cctgttttag aaagcagtca ttttgaatat
    16441 gaatttgata taccagaaat agagtacttc ttacgtatag acgcaaatgc atatacccgt
    16501 atcattaata acctattaca aaatattatt acccatagta gtggcaacaa aatgacattg
    16561 agaatttttg aaaacaaaga gcaagctcaa attataataa cagataatgg gaaaggtata
    16621 tcttcagaca atctcccaca tatttttgaa aggttgtacc aatgcgacca ttcacgagct
    16681 tcaaagggaa atggtttagg cttggcgatt gcaaaggaac ttattaacgc tcataaggga
    16741 aatattaccg ccaacagcac tcccggtatg ggaacagaat ttacaatatt gcttcctaaa
    16801 gccctgtaaa agtacgaggc tttcttactc taaaacaaga taaaagcaag attatggcaa
    16861 ggttttggca aggttcatgt tttataattc taattgtagt tgattttgac gttgtatcaa
    16921 ctatcttttg tagaaacaaa tttattaaaa gtgaggaaat tatatatgaa tgattttgtg
    16981 attgaaacaa agcaacttac aaaaatttat gggaatcaaa cagtagttga caaagtcaat
    17041 ctccatgtaa aaaaaggccg aatatatggt ctgttaggac gcaacggagc tgggaaaacc
    17101 acaattatga aaatgatttt aggattgact tcaatcacgt atggcgaggt agatgtattt
    17161 ggagagaata ttaagggatg tgaaaaacga gtatatcccc gtatcggtgc aattatcgaa
    17221 acgccaggat tttatcctaa tctgacagga acggagaact tggagatttt tgcaaaactt
    17281 cgtggtacag ccgcccctaa ttctgtaaaa agagcattgg agattgtagg cttaccttat
    17341 aaaaataaaa agctgtttag taaatattca cttggcatga aacagcgact tggtattgcc
    17401 aacgctatcc tgcatgaccc ggaactgtta gttttagatg agccaaccaa tggacttgac
    17461 cctattggta ttgcggagat gagaaagttt attagggact tgagcgttga gcatggaaag
    17521 acaattctta tctccagtca tattctttca gaaatctcat tgttggctga tgatattgga
    17581 attatcgacc acggtgttct tttggaagaa agtagtatga gtgaactaga aaagaaaaac
    17641 agtaaatata tcctgctaca agtttcagat attccaaaga catcacttat tttagagcgt
    17701 caatttaaca cgaaggatta ttccgttcaa gatgaccaca ctttacgcct ttataacact
    17761 actctggata tgggtgaaat caataaagca cttgtaatgc agaatgtaac tgttattagt
    17821 tctcaacttt gtaatgatac tttagaggac tactttaaaa aaatcacagg aggagagggc
    17881 attgcttaaa cttattcaaa cagaatttct taaactgcgt cgtaggaaac ttatttggct
    17941 gatgttgttg tctgctctca ttatgccgtt tttcgcacta ctatacttca attattttgg
    18001 taaaacaggt gttgagccaa caaagtttta taaatggtct gcatttggtt atacactttg
    18061 gattattttg cccgttgttt tgggtatatt ttgcaccatg cttatacacg aagaaaacca
    18121 gtatgatatg ctcaaacagc tttggattgt acctattagt aaaatgggat acttttttag
    18181 taaatttttc gttgttttga tttactctat ttgttttatg ctgattacag ccgttgcttc
    18241 tgtgttattt agtgtacttt ctggatatgt cgtatttagc tgggcaagca ttttatattt
    18301 gttgaaaaaa tgtttagaaa ttggtgtaat cactgctttt gtaatgttgc cgattttggc
    18361 aatcgctaca tctcaaaaag gatacattct cccaatttgt atcacattgg tatatgcctt
    18421 ttccggtttt gttataatga caataaatat gtatttacac ccattatcca gtatgggagt
    18481 tattatcatg agaaataaag acattccagg tcttatattt tcacaggaaa ttaatgtccc
    18541 attagcattt ctttgtattt gtatttggag tattgtatca gtattgtttg caagcattgc
    18601 actaggaaga agaaagtgag gtgtagataa tgtggaaatt actttgggct gaatgtcaaa
    18661 aaattcgtcg ttcaaaaatt gtttggatta cattttttgc atccattatg atagcagtca
    18721 tagtttttgc aggagggcag gatgtatata atgacccaga tttacattat ggcttaaaga
    18781 gcgtttatga cggttcacgg tatatagaca atgcaggttg gtatatggac gcggtacaac
    18841 cttggtcaac tttttttgtt cttcctgctg tcattgccct attaggaagc tatattattt
    18901 gtcgtgaaga agaggaggac actattaaat ccctgcgtct tattcccata aatgaaacaa
    18961 aattaaccat agcaaaaatg attattactt ttatattcag tatacttctt tatttgttac
    19021 tctttactat aacatttttg actgaatccg ttttacattt ttccgattta tcgacaaaac
    19081 tggttttaag ttgcatgaaa gagtattttc ttgatggcat aggtgtattc tttgcaattt
    19141 ctcccattat tgccttggta tcgcgcatga aaaaaggata ttggcttgca ttagtattca
    19201 cagaagttta ttctattgct ggactatttg cgggtatgtc aaatgtctta caaacctttt
    19261 ttcctattgc agcaatattt aatatttctg gatactatat aactactgga gaaaaaatta
    19321 tggggagtat cataagttta ttactttgtg cctgcctttc tgcatttata ctgaaagggc
    19381 taaaacacaa tgaaaaaaat tgaaataggt atatcaaaat gaaaaagata aaaaaactga
    19441 ttattctaat tgtattcttg tttctttttg gcatgttaca ctgttatact gaatggaaat
    19501 tcaacaatga cccacctaaa ggggtaatag aaagaataaa tgagtggact gataagattg
    19561 gactggatta gtaacttatg ttaattatag tgaatgtaat attagcaagt tattgtttcg
    19621 tattttaata ctataacttt aaatatttgg ttttaatctt ccgaacgaat ataaaaaaac
    19681 tgtcacagag gcaacatatt tttgaatatt tataaagtgg tagttttgat tttcaaagct
    19741 gccgcctttt cttctatata agcaaactta tcctcaacaa agtgtaaaac atggtacatt
    19801 ttaagaaaaa agtaccacag acacaagcaa taaaagaaac gccgagaacc tacaaaaacg
    19861 tagtgcttat gcagatttac gacgccttct attttctcaa ccgtcttaat gaccttgtac
    19921 aaaagaaatt tttctaatat tttttataat cttatcttgt gatgtttttt atgtataaat
    19981 gacttaataa caaatccaat aaaaattatg gatattggta taattagaac gaggaattta
    20041 taatcattat aatgtgacat tattcttacc caactctcag aaaaaatata tcctatactg
    20101 attaatgaag tattccatat ggttattccc acgatagatg atattacaaa agttataata
    20161 ttttgacctg ctatacctgc tataaaagat atgtatgttc tacataaagg gattaatcta
    20221 catacacaaa cagaaataga agagtattta ttaaaataat cttgagatgc aaatattcct
    20281 ttctttgcct ttggacatat ctctattatt ttatttatga tagatttacc tccccaattt
    20341 cccactgtat aacaaaatat cgaaccaagt atacctgcaa ttatacttaa aattaaaatt
    20401 gtcagaaatc caaaatgatt tcttgcagca attgctccac ataaaggtaa aacaacttcg
    20461 ctaggtaatg gaaaacaagc atactcaatc ataattaata caaatacaga gattaatcca
    20521 tattgtaaaa taaaactatt gattacagac acttacttat ctatctcctt tcttatttaa
    20581 aggttttaag ggtacatatt ctaaggattc tcaccctata tttaaagaat caatctcttt
    20641 aaactattat atgtatttac acaaagcatt tataacatac tttaaaaata gtaccttaaa
    20701 ataagaaact taataaataa aaaaagatta cgtggctacg tcctactctc ccaggcag
//
LOCUS       DAMJYN010000263        18771 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.guided.073, whole genome shotgun sequence.
ACCESSION   DAMJYN010000263 DAMJYN010000000
VERSION     DAMJYN010000263.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18771)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18771)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18771
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.guided.073"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            249..926
                     /locus_tag="PC466_003898"
     CDS             249..926
                     /locus_tag="PC466_003898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2771201.1"
                     /translation="MYNLLVVDDDVDILNINQIYFSNIGFNVYTSETAKDAMDIVERI
                     VLDCIILDISLPDIDGYKMCNDIKEKVNIPIIFLSNYEHEEEKVRGFLAGGDDYITKP
                     YSLKELELRIYARMRQYKNITSVPNVLKFSALVINVNSRKVTFDGESIDLTTMEFEIL
                     LFLAENKEQVFSKIEIYNQVWKMPDIGDQHTVQVHIAQMRKKINSLSREHQYIQTVWG
                     KGYKFVP"
     gene            998..3013
                     /locus_tag="PC466_003899"
     CDS             998..3013
                     /locus_tag="PC466_003899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HDF2771202.1"
                     /translation="MKKYNILKGTLIVLIVSLLAIAGLNLLYKYDNKYTYKSIRASNG
                     ILTIDNDTFTKGKLVFLIDDWEFYNHKIFKPNDFTEQDIKPEYVFIGQYPDFSMRKGN
                     QSPYGNATYRMRIKNEGEDKLLSLELPEIFSASEVWINGEIVSKLGDVGTEKYRPKIK
                     NSVVSFIAKKDTEIIINVSNFSHYYSGLYYPPALGETKDISNMMFYRLLFYSIICFTT
                     FAIAIFSLSVWFLSNKSKLYLYFGCMCVFFAIHVSYPFVHLLGLPLVSFTYAVEDSSY
                     FMVVLCIICINGSISKIEEDKVYRFLILPLGITMSIISIVIPIILLPYDMYFVNIYGK
                     LIDIYKYIVFIYILMSSLVSIYKKTCSEHISSYILVSVNTVFGISILFDAVTSNRFEP
                     IFTGWQTEYCGFIIVILFSLMMINRNRIIIKENEKLTRNLEHEVEVRTNELTTLLNER
                     KKFLADVAHDLKAPVSAIQSFIDLIKVGNIHVDEETRTYLYAINQKSNEVQNRVRSLQ
                     EFTSQDKSIGISEKICLNDFIKEIYENNLPDTQACGVNFETYILEKKIYAKINKEMLT
                     RAFENLIYNALTFTPFDGKIILSMDKEDGFAIIKVSDNGKGIPPENIPKVFDRFFTER
                     DNNEPKGQGLGLYIVKSIIREHGGEIFVDSELGKGTVFTIKLSLCFL"
     gene            3063..3743
                     /locus_tag="PC466_003900"
     CDS             3063..3743
                     /locus_tag="PC466_003900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2771203.1"
                     /translation="MQTKILIIDGDKDNCQKLKGFLEEKEISIDLAYNCEEAIGKIFS
                     NKYDLIFLEIILTDGDGWTLCKKIRNVTTCPIVYMTYINEEQSILNALNSGGDDYLIK
                     PLNLEILYAKVKAILRRMNSYVNNNENNTKLEEYNRTSGVIKLEDKIIKLTPTENKLL
                     NFFIENPEKTLTTKEIYEHVWMNEYLEDNYSVVVAVNGLRKKIEKDYKNPQKIITIRG
                     AGYYFNKE"
     gene            4125..4823
                     /gene="vanR"
                     /locus_tag="PC466_003901"
     CDS             4125..4823
                     /gene="vanR"
                     /locus_tag="PC466_003901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002594737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanR-ABDEGLN family response regulator
                     transcription factor"
                     /protein_id="HDF2771204.1"
                     /translation="MSGKILVVDDERDIADLIEVYLTNENYIVYKFYSGLDALNCINL
                     NEFDLAILDVMLPGVNGFSLCQKIREKYTYPIIMLTAKDEETDKITGLTLGADDYVTK
                     PFRPLELVARVKAQIRRYKKYSGSLQSGEELSHIFSFLGLELNTQTYECHLNGKALSL
                     TPTEFSILHVLLKNKGSVVNSENLFHAIWKDEYYNKSNNTITVHIRHLREKLGDTVDE
                     AKYIKTIWGVGYKI"
     gene            4859..5974
                     /locus_tag="PC466_003902"
     CDS             4859..5974
                     /locus_tag="PC466_003902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2771205.1"
                     /translation="MKKINNFTYRKLRDKYKFIKREKNTEAYLKYKLYIMLAIYTGIV
                     LVLMFMADYTFSNFSNPLVKWLKLRRDVLFFLVFIIGYITIFNFYWKKPWNYLREIIN
                     ATHTIYQQNDELVELSKPLKEIEQQMNQIKMSVLLSQQAVKEAENKKNNLVMYLAHDI
                     RTPLTSVIGYLSLLKEIPNMDNSQKSKYTEVALDKAQYLEKLINELFEITRYNSNQIK
                     INFEKVDLYYMLLQLKDEFYPLLSEKGNRAILKANESLTIKADSEKLARVFNNILKNA
                     IAYSYPNTEIIISAVHKDSKVDIAFRNYGQTIPEEQLSAIFEKFNRLDEARKSDMGGA
                     GLGLSIAKEIINLHGGDITVQSKDEVTTFTISLPTSI"
     gene            6119..7006
                     /locus_tag="PC466_003903"
     CDS             6119..7006
                     /locus_tag="PC466_003903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2771206.1"
                     /translation="MELKIEHVTKKFKDKIAVEDVCLTLTPGVWGFLGANGAGKTTLM
                     RIITDIMKPTNGKILYNGKNIYIMGAEYRNLLGFLPQEFGFPQDFSVKDYLEYIAALK
                     DVPPREVKGKINNLLEILTLSDVKNKKIIKLSGGMKRRVGIAQAMLNDPKILIMDEPT
                     AGLDPGERVRFRNFISEFSHNRVVLISTHIVSDIEYISTQNAIMKSGKILDVGTTDKL
                     VKKVEGKVWECLISNRDISKYEMNLRIINQRSEKNNQVSIRYLAEKSQIDNSIAVEPR
                     LEDLYLWLFPEAVYSKEGK"
     gene            7007..8242
                     /locus_tag="PC466_003904"
     CDS             7007..8242
                     /locus_tag="PC466_003904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2771207.1"
                     /translation="MRIFYLEIKRVLHSRRTLILLLLALVLSALMAFLPITYEGINYL
                     DNNGKVVELSGLDAIKYKKTIYANNSEISSGVVTPKKLKHALNIWKKTEEKYGKVGSE
                     DFPLDIYSKSILPIRPLLNRLPEAFANSETGFATELSEINTNDLDSFYEQCKTHLNDI
                     MKIERQTSSAQMKAQELYRKVDTPFEIYPGYSKDAFDYIIFYIFILLIICVAITAPTF
                     SGEYQTQSDSILRCTKHGHTRLAFTKILALFSIFIVMFVVCISIHLAISDLAFGTECL
                     KTSFQMLFSVISLVNINLLQAQILIAIGGLISILAMVSLTLFLSAKCKDSLTSMLIAF
                     SICLIPMGIGVSWIGYLLPPGGIGLKISLLYQMTSFNFLHLGGMSFWTPHIILFFSVI
                     EIPIFIFLAIRTYCKHQVS"
     gene            8624..9541
                     /gene="pstC"
                     /locus_tag="PC466_003905"
     CDS             8624..9541
                     /gene="pstC"
                     /locus_tag="PC466_003905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HDF2771208.1"
                     /translation="MIVKSRLVGLEKNDNNGNKTKYVIEKVAKNIFLLSALVAVASLL
                     LIIGFVFYKGLRPFIFEGYSFIDFLTGADWVPSANKFGISSMIVASIFATLGALVIGV
                     PVGILTSVFIAEVAPKRLAKIMSPAVELLAGIPSVLYGVFGLAVIVPTIQSIFNLPKG
                     QSLLAIVIVLAVMMLPTIISVSETAIRAVPKAYKEGSLALGASKIETIFKVVLPAAKS
                     GVLAAVVLGVGRALGETMAVILVAGNSPVMPTAITDSVRPLTTNIALEMGYAFGTHQE
                     MLFATGVVLFTFILILNLVLNKLSNKAVN"
     gene            9543..10367
                     /gene="pstA"
                     /locus_tag="PC466_003906"
     CDS             9543..10367
                     /gene="pstA"
                     /locus_tag="PC466_003906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003460575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HDF2771209.1"
                     /translation="MRKFKENLLKSLVYLSALFTIVSLVIIVGFIFIKGIGNMNFNFL
                     FSNYSASGDGGILPMIITTLYTVVVSIVVATPIGILAAIYLQEYAKKGKAVTAIRFAT
                     ESLSGIPSIVYGLFGGIFFVVTLKMGYSIVAGSLTVAIIILPVIIRTTEEALKTVPQA
                     YRESSLALGATKFQTLYKVVLPSAIPGILSGVILSVGRIIGESAAILLTAGTVAKMPG
                     GIFDSARTLTVHSYLLTKESGDIATAASIGIVLIVIVLALNMLARFVAKKLNKANY"
     gene            10386..11150
                     /gene="pstB"
                     /locus_tag="PC466_003907"
     CDS             10386..11150
                     /gene="pstB"
                     /locus_tag="PC466_003907"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HDF2771210.1"
                     /translation="MELIDKIKMSVKDLDLFYGDKQALKKINMDIKENKVTALIGPSG
                     CGKSTFIRTLNRMNDLIEDVTIKGNISVDGEDIYTSDDVINLRTKVGMVFQKPNPFPM
                     SIYDNVAYGPRTHGLRDKKQLDKIVEESLKGAAIWDEVKDRLKSSALGLSGGQQQRIC
                     IARAIAMRPEVILMDEPTSALDPISTLKVEELIEDLKKDYTIVIVTHNMQQAARISDE
                     TAFFLNGEVIEFSDTKTMFTTPVDKRTEDYITGRFG"
     gene            11178..11831
                     /gene="phoU"
                     /locus_tag="PC466_003908"
     CDS             11178..11831
                     /gene="phoU"
                     /locus_tag="PC466_003908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HDF2771211.1"
                     /translation="MVNNSLDISIDTLKEQTVLMMEKCEEAIEKSVTCMIEKDLEGAR
                     KVVEDDEEINKLREEIRDKSIELIVLKQPMARDLRFIYSLGNISIELERIGDYAANIA
                     REMLKIGGEAYIKELIDIPKMAKECKSMMSQTREALILFDASIAYDVGTKDDIVDGLY
                     EQVQIDCLKIMHENSNTIDQGVKLLLIGRYLERIGDHITNVCEKIIFAIEGKMVEIG"
     gene            11989..12858
                     /locus_tag="PC466_003909"
     CDS             11989..12858
                     /locus_tag="PC466_003909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HDF2771212.1"
                     /translation="MKLQKMGMRTIKTGISVTLCMILGNYLVENMFYSLVACIISVQD
                     TVKGSLKTGINRVEGTILGGIIGFIFAIIKAGDPFLCGLGVMCSIYLCNLFKIKSVVV
                     ACVTFLAIHLGVGNSDPVYYSLHRVLDTSVGVLFGVLVNYYVARPNYLNSVIDEFKKI
                     EELSMLLIEDKILRKENLNVEKFEEEVEKLEEIYSKLIDELDYSLSETNIEKIENALR
                     ICREIHFHMQSIELLENKLYLKEHTYKYLKKTYNVDKLDWNIDEEKSPVFNYHLMKIM
                     IEIELLRKLNKSY"
     gene            12945..14381
                     /locus_tag="PC466_003910"
     CDS             12945..14381
                     /locus_tag="PC466_003910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron hydrogenase"
                     /protein_id="HDF2771213.1"
                     /translation="MNTRNDNSKILEIYKMKLFGELVKAVWNDDIEDIENLPNKILNE
                     DLKDNLNNYFSGKFDKDTMVNLIRVTMGLDVTEDTDKNLKESLHEAVNLDEVKRPIIS
                     VISDACKYCDENNKEDESCKIRSKHINCNEEDVCSACGDCVSRCKLGAISDKIEFIPM
                     IKLLKDIKSPVYAIVAPAFVGQFGKDVSPGKLRTALKKIGFEDMIEVALAADMLTAKE
                     AYDYYEHMKKDEEGCFITSCCCPIWVSLIQNSFPQILENVSPSVSPMIACGRAVKILN
                     PDAKVVFIGPCMAKKKEAMLEDIKDAVDFVLTFKELQEIFDALELNPAIMDESNRVEA
                     SLSGRVYARTGGVSKAVKLSVRRIDKNIKFEEKAFEGTKECMDGLKKVLNKEIEATFI
                     EGMGCVGGCVGGPKRILSVEEGTKNVDEYSESTNMETPFDNLNVLQFLTSLGIKRVES
                     LGEKEEEKVKKIFSRDIKSNKKENKYKK"
     gene            14429..15256
                     /locus_tag="PC466_003911"
     CDS             14429..15256
                     /locus_tag="PC466_003911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HDF2771214.1"
                     /translation="MKIKDNKAVFHVFIRIFLIAVLILTGTLLEEKINNVPVENISSK
                     GENTLELLSQSNTLGEIIYKASQEETKGPGATSEKVAYITIDDGPSKYTNALLDILKE
                     NDVKATFFMLNQNMKNHKEEVRRVLEEENSIGFHSVSHDIHKLYKSPEVTVGEFNTCN
                     NTLQEITGQSSKLIRLPYGSKPYMPEGSYNKLMANDYLIWDWNLDTQDWKSSTSQIVS
                     NILYYGRKRDELVVLIHEKEQSLNALNNIIRILKERGYTILPITENITPKNFWQENL"
     misc_binding    15557..15819
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            15895..18561
                     /locus_tag="PC466_003912"
     CDS             15895..18561
                     /locus_tag="PC466_003912"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HDF2771215.1"
                     /translation="MENTNLSKTYNPKDFEARLYKKWMDEGYFKSKPNPDKKPFTIMM
                     PPPNITGQLHMGHALDHTLQDILIRWKRMDGYEAFWLPGTDHASIATEVKVVERIKKQ
                     EGKTKYEIGREEFLKRAWEWKDEFGGKISNQLKQLGDSCDWDKERFTMDEGCNEAVIE
                     FFVSLYEKGHIYRGNRIINWCPDCKTTLSDAEVEHEEHDGNFYHIKYPLKDSEDFLEI
                     ATTRPETMIGDTGIAVNPEDDRYKHLIGKTAILPLVGRELPIVADSYVDLEFGTGAVK
                     MTPAHDPNDFEVGLRHNLEQLNTMNEDGTMNEVCGKYEGMDRFECRKAIVADLKEQGY
                     LIKIKAHNHNVGTCYRCHTVVEPRLSEQWFVKMEELAKPAIDILKKGELEFVPDKFDK
                     TYLQWLENIRDWCISRQLWWGHQIPAYYCQECGEIVVARKMPDKCPKCGSTHFKQDED
                     ALDTWFSSALWPFSTLGWPNKTEALDYYYPTSVLVTGYDIIFFWVVRMAFAGMFCMNE
                     KPFDHVLVHGLVRDSQGRKMSKSLGNGIDPLEIIEQYGADALRFTLTTGNSPGNDMRF
                     YMERVEFARNFANKLWNASRFVFMNIDEDIIKNMTRESVKEDLTLADKWIISRANNIV
                     KEATNNMDKFDLGIALQKIYDFTWSEYCDWYIEMVKPRLYGEDANAKSAALYTLTYVL
                     EKILKLLHPYMPFITEEIYTHLPTVEGCIIVSEWPKYNEEDNMAEEEDMMNLLMEGIR
                     SIRNVRAEMNVPPSKKAKLIIIPSEEKIEAIELGKDYFITLASASNVEIAKDKSNVPE
                     DAVGVVIDGVEIFIPLNELVDFEKEIERLSKEKKKLEGEIKRVNGKLANQGFLAKAPE
                     SLIEEEKVKKEKFEEMIKSVEERLTNLESKIK"
BASE COUNT         7383 a         2029 c         3351 g         6008 t
ORIGIN      
        1 tttataagtg aaaatgactt taagctccat tctccaacaa tcggagactt taattagtat
       61 ttaataataa atcttaatgt tcaatacaat attcaagaat tgttcaaaaa tacttaagta
      121 ttatagtcta gtttgtaaag atattataaa ataataatac tagttatata tgaaaataaa
      181 acattataat ttgtaataat tataaaactt gagattatga ttaaaatacc tttgaatgga
      241 gtggtgtaat gtataattta ctggttgtag atgatgatgt tgatatttta aatataaatc
      301 aaatttattt ttctaatata ggttttaatg tatatacatc agagactgct aaagatgcta
      361 tggatatagt agagcgtata gttttagact gtataatttt ggatatttca ttgccagata
      421 tagatggata taaaatgtgc aatgatataa aagaaaaggt taacatacct ataatatttt
      481 tatctaatta tgagcatgaa gaagaaaaag ttcggggatt tttagctggg ggggatgatt
      541 atataacaaa accttatagt ttaaaagaac ttgaacttag aatatatgct cgtatgaggc
      601 agtacaaaaa tattacatca gttcctaatg tgttaaagtt ttcagcgtta gtaataaatg
      661 taaattcaag aaaagtaact tttgatggag aaagtataga tttaactact atggaatttg
      721 aaatattatt gtttctagct gaaaacaaag aacaagtatt ttcgaagata gagatatata
      781 accaagtttg gaaaatgcct gatattggag atcaacatac agtgcaggtt catattgcac
      841 agatgagaaa aaaaattaat tctttaagca gggagcatca atacattcaa accgtatggg
      901 gaaaaggata taagtttgta ccataagtga gatactgtaa ttaataaata gttcttgttt
      961 tatttaatac tactatgaaa gagatgtggt tgatgcaatg aaaaagtata atatactaaa
     1021 aggaactctc attgtattga tagtctctct gttggcaata gcaggattaa atcttctgta
     1081 taaatatgat aataaatata catataagtc tattagagca agtaatggaa ttttaactat
     1141 agataatgat actttcacta aaggtaaact tgtctttctg atagatgact gggagtttta
     1201 taatcataaa atatttaaac cgaatgattt tacagagcaa gatataaaac cagaatatgt
     1261 ttttataggt caatatccag atttttctat gagaaaaggg aatcagtcac catatgggaa
     1321 tgctacttat cgtatgagaa taaaaaatga aggtgaggat aagctactaa gtttagagct
     1381 tcctgagatt ttttccgcaa gtgaagtatg gataaatgga gaaatagttt ctaaattagg
     1441 agatgtagga acagaaaaat atagacccaa aattaaaaat tcagtagtaa gttttattgc
     1501 aaagaaagat acagaaatta taatcaatgt atcgaatttt tcacattatt atagtggttt
     1561 gtattatccg cctgcattag gagaaacaaa ggacataagt aatatgatgt tttatcgatt
     1621 acttttttat agtataattt gcttcacaac ttttgcaata gctatatttt cgttgtctgt
     1681 atggtttctt tcaaacaaaa gtaaacttta cttatatttt ggatgtatgt gtgttttctt
     1741 tgccatccat gtatcctatc cctttgtaca tttgttagga ctgcctttgg taagctttac
     1801 atatgcggtt gaagattcgt cctattttat ggtagtttta tgtattattt gtataaatgg
     1861 aagtatatcc aaaatagaag aagataaagt gtatagattt ttaattttac cattaggaat
     1921 tacaatgagt atcatatcta tagtgatacc aattattctt cttccatatg atatgtactt
     1981 tgtcaacata tatgggaaat taatagacat atataaatat attgtattta tatatatatt
     2041 aatgtcttcg ctggtttcaa tatataaaaa gacatgctct gagcatataa gttcttatat
     2101 tttagtttca gtaaacactg tttttggaat tagcatatta tttgatgcag ttactagtaa
     2161 tagatttgag cctatattta cagggtggca aacagaatat tgtggattta taattgttat
     2221 tttattttct cttatgatga taaacaggaa tagaataata ataaaagaga atgaaaaact
     2281 tacaaggaat cttgaacatg aagttgaagt gagaactaat gaacttacaa cattgttaaa
     2341 tgaacgtaaa aaattcttgg cagatgtggc acatgattta aaggcacctg tttcagctat
     2401 acaatcattt atagacttga taaaggttgg taatattcat gtagatgaag agacaagaac
     2461 ctatctttat gctataaatc aaaagtcaaa tgaagtacaa aatagagtac gtagtttgca
     2521 agaatttaca tcacaagata aaagcattgg tattagtgaa aaaatatgtc taaatgattt
     2581 tattaaagag atatatgaaa ataacttgcc agatacacaa gcatgtggtg taaactttga
     2641 aacttacata ttggagaaaa aaatatatgc aaagataaat aaagagatgc ttacaagagc
     2701 atttgagaat ttaatttata atgctttgac atttactcca tttgatggaa agataatttt
     2761 atcaatggat aaagaagatg gatttgcaat tattaaagtt tctgataatg gaaaaggtat
     2821 acctccagaa aatataccaa aggtatttga cagattcttt acagaaagag ataataatga
     2881 gccaaaaggg caagggctag ggttatatat tgtcaaatcc attataagag agcatggcgg
     2941 agaaatcttt gtagattcag aactaggaaa aggaactgtt tttacaataa aattaagtct
     3001 atgtttttta taataatagc ttatttaata taaaagaata atgatatttg ggagtgatta
     3061 taatgcaaac taagatattg ataatagatg gagacaagga taattgccag aagctaaaag
     3121 gatttctgga ggaaaaagaa ataagtatag atttagcata taattgtgaa gaagctattg
     3181 gaaaaatatt tagcaataaa tatgatttaa tatttttaga aataattcta actgatggtg
     3241 atggatggac tctttgtaaa aaaattagaa atgtaactac ttgtccaatt gtttatatga
     3301 cttatataaa tgaagaacaa agcattttaa atgctttaaa ttctggcgga gatgattact
     3361 taataaagcc tctaaattta gaaatattat atgcaaaagt aaaagctatt ttaagaagaa
     3421 tgaactcata tgtaaataat aatgaaaata atacaaaatt agaggaatat aatagaacta
     3481 gtggagtaat aaagttagaa gacaaaataa taaaattgac tccaacagaa aataagctgt
     3541 taaacttttt tatagagaat cctgaaaaga ctctgactac taaagagata tatgaacatg
     3601 tatggatgaa tgagtactta gaggataact atagtgtggt agttgcagtg aatggattaa
     3661 gaaagaaaat agagaaagat tataaaaatc ctcagaaaat tataacaata agaggagcag
     3721 gatattattt taataaagaa taataaatat attaatctca ttaataattg ttataaatgt
     3781 gaaatgctaa cgatatctaa actaaattat tataaaatag ctgactgtaa tttaattgat
     3841 aaagcctatt cttctagact ttgccagtta aattacagtc agttttatta tatgaaaaaa
     3901 tgcgtaacag aactattatt ttatagatta tatttgaaaa gatagataaa ttgtatatct
     3961 aaatctatat atattcattt ttatctttaa tatatgttaa ataataaaat agttacataa
     4021 taagattaag aatttcttaa taaattctaa tgtaaaaaat catataaaaa aattaaattt
     4081 agtataatat atataaatat atatagaaag gatgtttaaa gtctatgagt ggaaaaattt
     4141 tagttgtaga tgacgaacgt gatatagctg atttaataga agtctacctt acaaatgaaa
     4201 actatattgt ttataaattt tattctggtc ttgatgcact aaactgcatt aatttaaatg
     4261 aatttgacct tgcaatttta gatgttatgt tgccaggagt aaatggattt tctttatgcc
     4321 aaaaaatccg agaaaaatat acttatccaa tcattatgtt aacagctaag gatgaagaaa
     4381 cagacaagat tacaggctta actttaggtg cagatgatta tgttactaaa cctttccgac
     4441 ctttggaact tgttgctaga gtgaaggcac agattagaag atataagaaa tacagtggaa
     4501 gtttacaatc tggtgaagaa ctttcacata ttttttcttt tttaggtctg gaattgaata
     4561 cccaaacata tgaatgccat ttaaatggta aagctctttc acttactcca acagagtttt
     4621 ctattctaca tgtattattg aaaaataaag gctctgtggt aaattcagaa aatctttttc
     4681 atgctatctg gaaagatgaa tattacaata aaagtaacaa tactataaca gttcatattc
     4741 gccatcttcg tgaaaaatta ggtgatactg tagatgaagc aaaatatata aaaacaattt
     4801 ggggtgttgg ttacaagatt tgacacctat ttttcttgtc aagaagggat gtagtattat
     4861 gaaaaagatt aataatttta cttataggaa actaagagat aaatataaat ttataaaaag
     4921 agaaaaaaat acagaggcgt atttaaagta taaattatat ataatgttag ctatctatac
     4981 aggtatagta ttggttttaa tgtttatggc tgattatacg ttttcaaatt tttcaaatcc
     5041 tcttgttaaa tggcttaagt tgagaagaga tgtattattt tttttggttt ttataattgg
     5101 atatatcact attttcaatt tttattggaa aaaaccatgg aattatttaa gagaaatcat
     5161 caatgcaaca catactattt atcaacaaaa tgatgaattg gttgaactat ctaagccatt
     5221 aaaggaaata gagcaacaaa tgaaccaaat taagatgtct gttttgttaa gtcaacaagc
     5281 agtgaaagag gctgaaaata aaaagaataa ccttgtgatg tatctagcac atgatataag
     5341 gacaccactt acttcagtta ttgggtattt gagcttatta aaagaaatac ctaatatgga
     5401 taattctcaa aaatctaagt atactgaagt tgcacttgac aaagcacaat atttagaaaa
     5461 acttatcaat gaactttttg aaataacacg atataattct aatcaaatca aaattaattt
     5521 cgaaaaagta gacctatatt atatgttact tcaattaaag gatgaatttt acccattgct
     5581 gtctgaaaaa ggaaatagag ccattctaaa agcaaatgaa agtttaacaa taaaagcaga
     5641 ttctgaaaaa cttgcaagag tgtttaataa tatcttgaaa aatgctattg cttacagcta
     5701 tcctaataca gaaattatta tctcagcggt tcataaagac agcaaggtag atattgcttt
     5761 tagaaattat ggacagacaa ttccagaaga acaactttct gctatatttg aaaagttcaa
     5821 tcgtttagat gaagctagaa aatctgatat gggtggtgca ggtttagggc tttctatagc
     5881 taaggaaatt ataaatttgc atggtggtga tattactgtt caaagtaaag atgaagtcac
     5941 aacatttact atatcgcttc ctacatctat ttagtaaaat ataaatcaaa tattaggatt
     6001 ttcttaagaa attatctatt taatattaaa attatgagtg tctttgttta gtaaaataaa
     6061 tactaagcaa gacacttttg tttttgcagg taagtagata aagagaggag tttcaaatat
     6121 ggaattaaaa attgaacatg tgacaaaaaa atttaaggat aaaattgctg tagaagatgt
     6181 ttgccttacc ttaacaccag gtgtgtgggg atttctagga gcaaacggag caggtaaaac
     6241 taccttgatg agaattatta cagacattat gaaacctacc aatggcaaaa ttctgtataa
     6301 tggaaaaaat atttatataa tgggtgctga gtacagaaat ttactgggat ttttaccaca
     6361 agaatttggt ttcccacagg atttttctgt aaaagattat ttagaatata tagcagcatt
     6421 gaaagatgta ccaccaagag aagtaaaagg aaaaattaat aatctattgg aaattcttac
     6481 attatctgat gtaaaaaata aaaagattat taaattatct ggtggaatga aacgacgagt
     6541 gggaattgca caagccatgt taaatgaccc taaaatcctt ataatggatg aaccaacagc
     6601 agggcttgac cctggtgagc gagtgagatt tcgtaatttt atttcagaat tttctcataa
     6661 tcgtgttgtc ctaatatcta ctcacattgt atctgatatt gagtacatat caactcaaaa
     6721 tgctattatg aaaagtggaa aaattcttga tgtgggaaca accgataaac tggttaagaa
     6781 agtagagggc aaagtatggg aatgtcttat atcaaataga gatatttcaa aatatgaaat
     6841 gaatttacgt ataatcaatc agcgtagtga aaaaaacaat caagtatcta ttcgttactt
     6901 ggcagaaaag tcacaaattg ataactctat tgctgttgaa ccacgactag aagatttata
     6961 tttatggtta tttccagaag cagtttatag taaggagggg aaataaatgc gtatttttta
     7021 tttggaaatt aaacgagtgt tgcactcacg tcgtacatta attttattat tgttggcatt
     7081 ggttttatct gcattgatgg cttttcttcc aattacttac gagggtatca attatttaga
     7141 taataatggc aaggtagttg aattgagtgg tttagatgct attaaatata aaaaaacaat
     7201 ttatgctaat aatagtgaaa ttagtagtgg agttgtaaca ccaaaaaaat taaagcatgc
     7261 tttaaatata tggaaaaaaa cagaagaaaa gtatggtaaa gtaggtagtg aagatttccc
     7321 actagatatt tattctaaaa gtattttacc aatacgccca ttgttgaata gacttcctga
     7381 agcatttgct aattcagaaa caggatttgc aacagaatta tcagaaataa atacaaatga
     7441 tttagattct ttttatgaac aatgcaaaac tcatttaaat gatattatga agattgaacg
     7501 acaaacttcc agtgcacaaa tgaaagctca agaactttat agaaaagtag atactccatt
     7561 tgagatatac ccaggttatt ctaaagatgc tttcgattat ataatatttt acatttttat
     7621 attattaatt atatgtgttg caattactgc acctactttt tctggtgagt atcagacaca
     7681 atcagatagc atccttcgtt gtacgaaaca tggacatact cgtctagcgt ttactaaaat
     7741 attagctcta ttttctatat ttatagtaat gtttgttgta tgtatttcta tccatttggc
     7801 aatttctgat ttagcttttg gtactgaatg tttgaaaacc tcatttcaaa tgttgttttc
     7861 tgtcattagt ctagtaaata taaatttact acaagcacag attcttatag ctattggtgg
     7921 tctaatttca atacttgcaa tggttagttt aacattattt ttatctgcaa aatgtaagga
     7981 ttctcttact tctatgctga ttgctttttc tatttgctta attcctatgg gaataggtgt
     8041 tagttggatt ggatacctat taccaccagg gggaattggt cttaagatta gtttattata
     8101 tcaaatgaca tcatttaatt tcttacactt aggaggtatg agtttttgga caccacacat
     8161 tatactgttt ttctcagtga tagaaatacc tatttttata tttttggcta ttcgtaccta
     8221 ttgcaaacat caagtatcat aacaatttga tagaaataat agtgatataa actagaggat
     8281 acgataatta tatatgtagt ataaaagtta aatttagtta acaaatctta atagcagata
     8341 taggtaataa attatacata aactgtatta ttatctatat ctgctatttt aatatagaga
     8401 aacaacagta tattgtaaag taaatgtcaa atatagtttt aaaagtaaaa ttaatgttaa
     8461 aaaagtaaat ataattttac acttgcttaa cttaatccta atatagattt aacttaaaaa
     8521 aagtagaata aaagtacagg aaatttgatg aagacgaatt ataaaaaatt aaattttgaa
     8581 tacagaacga aaatcgataa gtatatttta atgggagggt attatgatag taaaatctag
     8641 attagtaggt ttagaaaaaa atgacaataa tggcaataag acaaaatacg taattgaaaa
     8701 agtagcaaaa aatatttttc tacttagtgc tttagtagca gttgcaagtt tacttttgat
     8761 aataggattc gtattttata aaggcttaag accatttata tttgaaggat attcatttat
     8821 agacttttta actggtgcag attgggttcc ttctgccaat aaatttggaa tatcatctat
     8881 gatagtagca tcaatatttg caacacttgg agcacttgtg ataggagtac ctgttggtat
     8941 attaacctct gtatttatag cagaagtagc acctaaaaga ttagcaaaaa taatgtcacc
     9001 agcagttgaa cttttagcag gtataccttc agtattatat ggtgtatttg gtcttgcagt
     9061 gatagttcca actatacaaa gtatatttaa tcttccaaaa ggtcaaagtt tgttagcaat
     9121 agtaatagta ttagcagtaa tgatgttacc aacaataata tctgtatcag aaacagcaat
     9181 aagagcagta ccaaaagcat acaaagaagg ttcattagca cttggtgcat caaaaataga
     9241 aacaatattc aaagttgtac tacctgctgc gaaatctgga gtattagctg cagtagtatt
     9301 aggagtagga agagctttag gtgaaacaat ggcagtaata cttgttgcag gaaactcacc
     9361 agttatgcca actgcaataa cagatagtgt aagaccactt acaactaata tagcacttga
     9421 aatgggatac gcatttggta cacatcaaga aatgttattt gcaactggag tagtattgtt
     9481 tacatttata ttaattttaa acttagtttt aaataaactt tcaaataagg cggtaaatta
     9541 agatgagaaa gttcaaagag aatctattga agtcattagt atatctatca gcactattta
     9601 caatagtatc attagtcatt atagtgggat ttatatttat aaagggaatt ggcaacatga
     9661 attttaattt cttatttagc aattattcag catcaggtga tggtggtata cttccaatga
     9721 taattacaac attatataca gtagtagttt ctatagttgt agcaactcct ataggaatat
     9781 tggctgctat atatttacaa gaatatgcta aaaaaggaaa agcagttaca gctataagat
     9841 ttgcaactga aagtttatca gggataccat ctatagtata tggattattt ggaggaattt
     9901 tctttgtagt tacattaaaa atgggatatt ccatagttgc aggttcactt acagttgcaa
     9961 taataatatt accagtaata attcgtacaa cagaagaagc tttaaaaaca gttcctcaag
    10021 cttatagaga atcatcattg gcattaggag ctacaaaatt tcaaacttta tataaggtag
    10081 tacttccaag tgcaatacca ggaatcttat ctggagtaat cttatcagtt ggtcgtataa
    10141 ttggagaatc agctgcaata ttacttacag caggtactgt agccaagatg ccaggtggaa
    10201 tatttgatag tgcaagaaca ttaactgtac actcatactt actgactaaa gagagtggag
    10261 atatagcaac agcagccagt ataggaattg ttttaatagt aattgtatta gcactaaaca
    10321 tgctagcaag atttgttgct aagaaattaa ataaagctaa ttattaaatt taagaggtgt
    10381 gaataatgga attaatcgat aagataaaaa tgagtgtaaa agatttggat ttattttatg
    10441 gtgataagca agcattaaag aaaataaata tggatataaa agagaataag gttactgctt
    10501 taataggtcc atctggatgc ggaaaatcaa cttttataag aacgttaaat agaatgaatg
    10561 acttaatcga agatgtaaca attaaaggaa acatttctgt tgatggagag gacatatata
    10621 cctcagatga tgttataaat cttcgtacta aagtaggaat ggtatttcaa aaaccaaatc
    10681 catttcctat gagtatatat gataatgtgg catatggtcc tcgtacacat ggactaagag
    10741 ataagaagca attagataaa attgtagaag aaagcttaaa aggtgcagct atttgggatg
    10801 aggttaaaga caggcttaaa tcatctgcac taggactttc tggtggtcaa caacagcgta
    10861 tatgtatagc aagagcaatt gctatgagac cagaagttat tcttatggat gaacctacat
    10921 ctgctttaga cccaatttca acattaaaag tagaggaact tatagaggat ttaaaaaaag
    10981 actacacaat agtcatagtt acacataata tgcaacaagc tgctcgtata tcagatgaaa
    11041 cagctttttt cttaaatgga gaggttatag aatttagcga tacaaaaact atgtttacca
    11101 ctcctgtaga taaaagaaca gaagactata taacaggtag atttggttaa aatatataac
    11161 tataaaggag ttagacaatg gtcaataata gtttagatat aagtattgat actttaaaag
    11221 aacaaacagt acttatgatg gaaaaatgtg aagaagcaat agaaaagtct gtgacttgta
    11281 tgatagagaa ggatttagag ggtgcaagaa aagtagtaga agatgatgaa gaaataaata
    11341 aattaagaga agaaataaga gataagagta tagagctaat agtattaaag caaccaatgg
    11401 caagggactt aagatttatt tattcattag gtaatatatc gatagagttg gaaagaatag
    11461 gagattatgc agcaaatata gctagagaaa tgttgaagat aggtggagag gcttatataa
    11521 aagagctgat agatattcct aagatggcaa aagaatgtaa gtctatgatg tctcagacta
    11581 gagaagcttt aatcttattt gatgcaagta tagcttatga tgttggaact aaagatgata
    11641 ttgtagatgg attgtatgaa caagtacaaa ttgattgttt aaaaataatg catgaaaatt
    11701 caaatactat agaccaagga gtaaaacttc tacttatagg aagatacctt gaaagaattg
    11761 gagaccatat aacaaatgta tgtgagaaga taatttttgc aattgagggt aaaatggttg
    11821 agataggata aaaaactgct ttaaagcagt ttttttattg tctaaattaa gaaagaattg
    11881 ataaaaaaat atgattaatg ggtaaattta aaaaattgtg atatactagg aacatattaa
    11941 atatgaggat gcgtatttta tataaggtgc tttttaggag gtggaacttt gaaacttcaa
    12001 aagatgggta tgaggactat aaaaacagga attagtgtca ctttatgtat gattcttggt
    12061 aactatctag tagagaatat gttttattct ctagtagcat gtataatttc tgttcaagat
    12121 acggtaaaag gttctttaaa gacaggaatc aatagagtgg aaggtactat tttaggtggt
    12181 ataataggat tcatatttgc catcattaaa gctggagacc cttttttatg tggtctagga
    12241 gtaatgtgct caatatattt atgcaatctg tttaaaataa agtcagtagt agttgcctgt
    12301 gtaacctttc tggctataca tctaggtgta ggaaatagtg accctgtgta ttattcttta
    12361 catagagtgt tagatacatc tgtaggtgtt ttgtttggag tacttgttaa ttattatgtg
    12421 gctagaccaa attatctaaa tagtgttata gatgaattta aaaagataga agaactttca
    12481 atgttactta ttgaagataa aattcttaga aaagaaaatt taaatgtaga gaaatttgaa
    12541 gaagaagtag aaaaattaga agaaatatat tcaaaactta ttgatgagtt ggattatagt
    12601 ttgagtgaaa ctaatataga aaaaattgag aatgccttaa ggatatgtag agaaatacat
    12661 tttcatatgc agtctataga gttacttgaa aataaacttt atttgaaaga gcatacatat
    12721 aaatacctta agaaaacata taatgtggat aagctagact ggaatataga tgaagaaaaa
    12781 agccccgtat tcaactatca tctaatgaaa ataatgattg aaatagagtt gttgagaaag
    12841 ctaaataaat catattaata atagtagtta aataataaat aaaaaatagt atctttgtaa
    12901 atattaaaca tatataagtt taatttatgg aggtactatt ttttatgaat actagaaatg
    12961 acaattctaa aatactagaa atatataaaa tgaagctttt tggcgaactt gtaaaagcag
    13021 tgtggaatga tgatatagag gatattgaaa acttacctaa taaaatttta aatgaagatt
    13081 taaaggataa tttaaataat tattttagtg gaaaatttga taaagatact atggtaaatt
    13141 taattagggt aactatggga ttggatgtga cagaagatac agataaaaat ttaaaagagt
    13201 cactacatga agctgtaaat ttagatgaag tcaaaagacc aataatatct gtaatatcag
    13261 atgcttgcaa atattgtgat gaaaataata aggaagatga gtcatgtaag ataagaagta
    13321 agcatattaa ttgtaatgag gaagatgtat gtagtgcttg tggtgattgt gtatcaagat
    13381 gtaagttggg tgcaatttca gataaaatag aatttatacc aatgataaaa ttgttaaaag
    13441 atataaagag ccctgtatat gcaatagttg caccagcttt tgtaggacag tttgggaaag
    13501 atgtaagccc tggtaaatta agaactgcat taaaaaagat aggatttgaa gatatgatag
    13561 aagttgcttt ggcagcagat atgcttactg caaaagaagc atatgattat tatgagcata
    13621 tgaaaaagga cgaagaagga tgctttataa ctagttgttg ctgtcctatt tgggttagtt
    13681 tgatacaaaa tagttttcct cagatattgg agaatgtatc accatccgtt tctcctatga
    13741 ttgcttgtgg gagagctgta aaaattttaa atccagatgc taaagttgta ttcataggtc
    13801 cttgtatggc aaaaaagaaa gaagcaatgt tagaagatat aaaagatgca gttgattttg
    13861 tgcttacatt taaagagttg caagaaatat ttgatgcatt agagttaaat ccagcaataa
    13921 tggatgagag taatagagta gaggcgtccc tttcaggtag agtttatgct agaacaggag
    13981 gtgtaagtaa agcagttaag ttatcagtca gaagaattga caaaaatata aaatttgaag
    14041 aaaaggcatt tgaaggaaca aaagagtgca tggacggtct aaagaaagtt ctaaataaag
    14101 aaatagaagc tacatttata gaaggaatgg ggtgtgtagg aggctgtgta ggaggtccga
    14161 agcgtatttt aagtgtggaa gaaggtacta agaatgttga tgaatatagt gaaagtacga
    14221 atatggaaac tccatttgat aatttaaatg tattacaatt tttaacttct ttgggaatca
    14281 aaagagtaga atctttagga gaaaaagaag aagaaaaggt taaaaaaata tttagtagag
    14341 atataaaaag taataagaaa gagaataaat ataaaaaata actttttaag tcttaaactt
    14401 atgcttttat aaaagggaga tatgggggat gaaaattaaa gataataagg ctgtttttca
    14461 tgtatttata aggatatttc ttatagctgt tttaatttta actggaacat tattggagga
    14521 aaaaattaat aatgttccag ttgaaaatat aagttcaaaa ggtgaaaata cactggaact
    14581 gctttctcaa agtaatactt taggagaaat catatacaaa gcatctcaag aagaaacaaa
    14641 aggtccaggg gctacttctg aaaaagtagc atacataaca atagatgatg gtccatcaaa
    14701 atatacaaat gcactacttg atattttaaa agaaaatgat gtcaaagcga cattttttat
    14761 gcttaatcaa aatatgaaaa atcacaagga agaagtaagg agagtcttgg aagaggaaaa
    14821 ctcaataggt tttcatagtg taagtcatga tatacataag ttatataaaa gcccagaagt
    14881 aacagttggg gaatttaata catgcaataa tactctacaa gaaataactg gtcagagttc
    14941 aaaattaata agattaccat acggaagtaa accatatatg ccagaaggtt catataataa
    15001 acttatggca aatgattatt taatttggga ctggaatttg gatacacagg attggaagtc
    15061 ttctacaagt cagatagtaa gtaatatatt atattatgga agaaaaagag atgaattagt
    15121 agtattaatt catgagaaag agcaaagttt aaatgcttta aataatatta taagaatctt
    15181 aaaagagaga ggatatacaa tattgccaat tacagaaaat ataacaccta aaaatttctg
    15241 gcaagaaaac ttataataaa tttaaatata gtaaaagata aagtaaatta tttataaaat
    15301 aaaacatata atataaaaaa tacgaataag aggtatactg taaggataat ataatataaa
    15361 attaatgaga aagcattaaa attaaaataa aataatcttg caattattga cattataaga
    15421 cagaataact gtaaaaacat attttaaaat ataacaacta tataaaagag aatagacata
    15481 attaagaaaa ttcagaaaaa ataaaataaa aataattgac aaagagaata atatttgtat
    15541 ataataatat gtaatattaa agactgagaa gaagaggagt aagtaaatac tactaaaaga
    15601 gaggaaaatt cactggctgt aagattttct aagtataaga tttactgaat gtagctttgg
    15661 agtttctaaa ctgaactata agtaagttta gacggttaga accgttaaat tctttgagag
    15721 tcaaagttga taaaataaca ttaactaata atttaattat atgttaatgt attttaagct
    15781 ttggaattaa ggtggtaacg cgagcttttc gtccttttta aagaggatga agagctcttt
    15841 tttatttcta aagatattta aaaaatttat ttataaaata caggaggcag gacaatggaa
    15901 aatacgaatt tatcaaaaac ttataaccca aaagattttg aggctaggct atataaaaaa
    15961 tggatggatg aagggtattt taaatctaaa ccaaatccag ataaaaaacc atttacaata
    16021 atgatgccac caccaaatat aacagggcaa ttgcatatgg gacacgctct tgaccataca
    16081 cttcaagata tattaatcag atggaaacgt atggatggat atgaagcttt ttggcttcca
    16141 ggaactgacc atgcttctat agcaacagaa gttaaagttg ttgaaagaat aaaaaaacaa
    16201 gaaggcaaga caaagtatga aataggtaga gaagaatttt taaagagagc ctgggaatgg
    16261 aaagatgaat ttggaggaaa aatatctaat cagcttaaac aactaggtga ttcttgtgat
    16321 tgggataaag aaagatttac tatggatgaa gggtgtaatg aagcagttat agaatttttt
    16381 gtaagcctat atgaaaaagg tcacatatac agaggaaata gaataataaa ctggtgccca
    16441 gattgcaaaa ctactttatc agatgcagaa gttgaacatg aagaacacga cggaaacttt
    16501 tatcatataa agtacccact aaaagatagt gaagactttt tagaaatagc tacaactaga
    16561 cctgagacaa tgataggaga tactggtata gcagtaaatc cagaagatga tagatataaa
    16621 catttaatag gaaaaacagc aatacttcca ttagtaggaa gagaacttcc aatagttgca
    16681 gatagttatg ttgatttaga gtttggaact ggtgcagtta agatgactcc agcacatgac
    16741 cctaatgatt ttgaagtagg attaagacat aatcttgagc agttaaatac tatgaatgaa
    16801 gatggaacta tgaatgaagt ttgtggaaaa tatgaaggta tggatagatt tgagtgtaga
    16861 aaagctatcg tagcagactt aaaagaacaa ggttacctaa ttaagataaa agcgcataat
    16921 cataatgtag gaacttgtta tagatgccat acagtagttg agcctagatt atcagagcaa
    16981 tggtttgtta agatggaaga acttgcaaaa ccagctatag atattcttaa aaaaggagaa
    17041 ttagaatttg ttccagataa atttgataaa acttatttac aatggctaga aaatataaga
    17101 gattggtgta tatcaagaca attatggtgg ggtcatcaaa taccagctta ttattgtcaa
    17161 gagtgtggag aaatagtagt tgctagaaaa atgccagata agtgtcctaa atgtggaagc
    17221 actcatttta aacaagatga agatgcctta gatacttggt tcagttctgc attatggcct
    17281 ttctctactc taggatggcc aaataagact gaagctttag attattatta tccaacaagt
    17341 gtacttgtta caggatacga tataatattc ttctgggtag ttagaatggc atttgcaggt
    17401 atgttctgta tgaatgaaaa gccatttgac catgttttgg ttcatggatt agtaagagat
    17461 tctcaaggta gaaaaatgag taaatcttta ggaaatggta tagacccatt ggagataatc
    17521 gagcaatatg gagctgatgc cctaagattt acattaacaa ctggaaattc cccaggaaat
    17581 gatatgagat tctatatgga aagagtagaa tttgctagaa actttgcaaa taagttgtgg
    17641 aatgcatcaa gatttgtatt tatgaatatt gatgaagata taattaaaaa catgactaga
    17701 gaaagtgtta aagaggactt aactctagct gataaatgga taatatcaag agcaaataat
    17761 attgtaaaag aagcaactaa taacatggat aagtttgatt taggaatagc acttcaaaag
    17821 atatacgatt ttacttggtc agaatactgt gactggtata ttgaaatggt taaacctaga
    17881 ttatatgggg aagatgcaaa tgctaaatct gcagcattat atacattaac ttatgttctt
    17941 gaaaaaatat taaaattatt acatccatac atgccattta taacagagga aatatatact
    18001 catcttccta ctgttgaagg atgtataata gtatctgaat ggccaaaata taatgaagaa
    18061 gataacatgg ctgaagaaga agatatgatg aacttattga tggaaggtat aagaagtata
    18121 agaaatgtga gagcagaaat gaatgtacca ccttctaaga aagctaaatt gataataatc
    18181 ccaagtgaag aaaaaataga agctattgag cttggtaaag actattttat aactctagca
    18241 tctgcttcaa atgtagagat agcaaaagat aaatctaatg ttccagaaga tgcagttgga
    18301 gtagttattg atggtgttga aatatttata cctcttaatg aattagttga ttttgaaaaa
    18361 gaaattgaga gattgtctaa agaaaagaaa aagttagaag gcgaaataaa gagagttaat
    18421 ggaaagcttg caaatcaagg tttcttagca aaagctcctg aaagtttaat tgaagaagaa
    18481 aaagtaaaaa aagaaaaatt tgaagagatg attaaatctg ttgaggaaag attaacaaat
    18541 ttagaatcta aaataaaata aatataagaa ttagtaaaaa catacaaaaa gtatatattc
    18601 tatacttttt gtatgttttt ctttatatat atacaaatat gatgttataa ttctttacag
    18661 atgtgttata tttttatttt atgttgtgaa tatatgaatt ttatgtctta aaatttataa
    18721 gcaataaaaa tttgatatat tatgatgttt aatatagggt aataaataca t
//
LOCUS       DAMJYN010000264        16484 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.guided.083, whole genome shotgun sequence.
ACCESSION   DAMJYN010000264 DAMJYN010000000
VERSION     DAMJYN010000264.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16484)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16484)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16484
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.guided.083"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(116..808)
                     /locus_tag="PC466_003913"
     CDS             complement(116..808)
                     /locus_tag="PC466_003913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HDF2771216.1"
                     /translation="MKSLNATEKIIDYIKLNILNGTFKINSKLPSERKIADLFNISRI
                     PVRNAINILCKEGILRAVPYSSPIVEGFKKVDLFDDGEIYKNHNIQEFYVESLRARQL
                     IESEATKLAILNATSKELQKIKYTYLKSIEELDKVSHGLIEECYDADLQFHKEIILAS
                     HNPIFIKYYELIPKTVSSNQYFGFKYRNSLKDMISHHNKIMMAFDSKDSYLGYTSMYN
                     HLEDVIQLFQHD"
     gene            complement(834..2021)
                     /locus_tag="PC466_003914"
     CDS             complement(834..2021)
                     /locus_tag="PC466_003914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2771217.1"
                     /translation="MKKISNQKLLLLSIVTFFWFSQYVYIPFQNPYLSACNVSTNMIG
                     IIIGAYGISQCLLRIPVGVFADSINKHKIFILSGIFFAGLASLIRVFSPGGNGFLIAN
                     ILSGISSSTWISYMVHYTNFFSTEHQQKATSTIILVNNLGMLIGFVMSTLFYEKLGMT
                     ALCIMSVLSSVIGTILALNIKNHNSKKIPEKISIKKYLSICKDKRLVFFSFMALIQQG
                     IQMSTTMSFTTQILKNLGSSSTLIGLSSISYMVCAVASSGFASTKFCTKYGPKFWIPL
                     VFILVSAYCFLVPTIKNINIIFVLQVLPGISTGILLSYLTSESMKNVPKHQKSTAMGF
                     FQAIYAIGMSVFPMIVGKISEYTSIQYGYFILAIIAILASILSYTYYKKVDLTLNYDI
                     IQS"
     gene            2357..4234
                     /locus_tag="PC466_003915"
     CDS             2357..4234
                     /locus_tag="PC466_003915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF2771218.1"
                     /translation="MDYKNIAQEILLNVGGKENVNEVTHCMTRLRFKVKSASKVNKDK
                     LSKTEGVITVVESMGQIQVVIGNKVKTVYDEVIKIVPQSNDVGKKNESQEKQSIINSI
                     LSAVAGIFTPTIPAIAGVGMIKGILSVLAMYYMNKNGVDIKETQSYIILNAMADSIFY
                     FMPIILGYTAAKVFNANKIISMVLGATLCYPTFTALMAGEESVRFLGLAVTKATYTSS
                     VIPIIIAIWALSYVEKVLEKYIPEVIKIIMVPTLSLVVMLPATLFLFGPIGIYIGNVI
                     NFSYKYIYELSPALCGAFVGGLWCVLVIFGAHRALLPIGISDVAQTGRQNLLAFAGAA
                     NFSQAGAALGVFFKTKNQGLKTISMSATITALFGITEPAIYGANLRLKKPMVCAVICG
                     AFGGAIMGMGGAYGNAFANQGVLTIPVYAEAGALGFLSYLGGCAIAFFGSAISTYLVG
                     FEDLEESSNKENSFIKVETKDGVIDITSPVEGECIELSEVKDDVFASKAMGEGIAVLP
                     TKGVITAPTDCEVASLFPTLHAIGLKLDNGAEMLIHVGINTVELNGKYFTKHVNQGDL
                     VKKGDKLISFDIDKIKKAGYDVTTPVIVNNTFDFGQVVSCKSSYVSTNDNIISLVLAG
                     N"
     gene            4546..5952
                     /locus_tag="PC466_003916"
     CDS             4546..5952
                     /locus_tag="PC466_003916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HDF2771219.1"
                     /translation="MNTGFPKDFLWGASSSAFQVEGAWDKDNKGKTVADYNSFKKSHL
                     QADTKVASDFYHNYEEDIELMKELGMKTYRFSISWARIIPDGEGEINQKGLDFYNKII
                     DKLIECDIEPFVTLYHFDLPFKLVEKYNGWESRETVYAFERFAKICFKHFGDRVKYWQ
                     PHNEQNLIVRVEERINIYDETDSWKIDKMRAQMDYNLCLAHALAVNACHEMIKESKIG
                     AAVSSSVTYPLTSKPEDVYAARMNDNFKVYYMLDMHHYGEYPGYYMKYLEKRNTVPHM
                     EDGDKEILKKAKMDFIAVNYYRTNCAEALPEDSQHPFGLREGTVDFSMYGLFKMSMNP
                     NLEASEYGAAIDPSGLRVALNEYWQRYHLPVIITENGLGAKDILEDGKIHDDYRIDYL
                     RSHINACKLAIEDGVEMIGYCPWSFTDLLSSSQGFNKRYGLVYINRTDHEVLDLKRIK
                     KDSFYWYKEVIENNGIVK"
     gene            5980..6828
                     /locus_tag="PC466_003917"
     CDS             5980..6828
                     /locus_tag="PC466_003917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDF2771220.1"
                     /translation="MYITKVLNNSLLLAKDDNDEEIILMGKGIGHNYKAGSELNKKDI
                     EKIFVLHDENIKKSIIQLATEIDAEYFGIAQMIIAYGIEKYNLKLMNHIYLALTDHIA
                     FAVRRFKEGIMIENHYLFEIKEFNPKEYDIGKYAITVFKEVLGLDLPEEEIGNIAGHF
                     INAQQDNPYSDRNKRSAKIVNAILQIVHYHFSIVYNKESFYYRRFVMHLKAFSQRFLA
                     NEPSREKIDFIYEQVQKNCKEEYECVKKVGAYMYKEYSRELPRQEELYLMIHIHKILG
                     ELCENS"
     gene            7489..8181
                     /locus_tag="PC466_003918"
     CDS             7489..8181
                     /locus_tag="PC466_003918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003020373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2771221.1"
                     /translation="MNKVLIIDDDKDLCILLKKSISIEQIEANYCHSGRDGLVELSKQ
                     DYQLVVLDVMMPGMDGFETMEQIRKYSSIPILMLTSKSDNYSKVHGLRAGADDYLTKP
                     FEITEFTARVLSLIRRYTRFNPKNEEPQQLSFKGLLIDLDQHTVTTNGEPMLLPPKEF
                     GVLLYCARHQGKILTKQQIYEAVWGEPYVYDDSNIMAIISRLRKKIELDPSSPIYLQT
                     IKGIGYQFNTEV"
     gene            8178..9113
                     /locus_tag="PC466_003919"
     CDS             8178..9113
                     /locus_tag="PC466_003919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2771222.1"
                     /translation="MKMDEQTIILFLFLLSIGLLFLSIFAFSKLGHIHKRLKDIEEIL
                     ADVQIGNENRKILIKPCDVMAPLVYQLNEIVYDYENKLLSLKKSDKASKQLMTSLSHD
                     VRTPLTTLIGYLDAVHSGIVIGQEREEYLEIARRRAYDLKDYIDVLFDWFRLNSDEFT
                     LSIESVEIAELSRNILKDWIPIFHEKKLNFEIDIPENRLMVNLDPDGYSRVVNNLVQN
                     VLAHSKARQIKITMSEDSRMVLLRVDDDGVGIARENLPHIFERLYKCDKGRSEKGSGL
                     GLSIVSQMVERMGGQISVESEIGKYTVFTVSLPLI"
     gene            9261..10184
                     /locus_tag="PC466_003920"
     CDS             9261..10184
                     /locus_tag="PC466_003920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013273760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2771223.1"
                     /translation="MNNLIIETKNLTKQYGAQKSVSNLNIHVQKGRIYGLLGRNGAGK
                     TTTMKMLLGLTKPTTGEIKIFGQDIHNNEKKLLPRIGCLIESPGFYPNLTGTENLKIF
                     ARLRGIPKKNAVESALDVVGLPNNDKKLFSQYSLGMKQRLAIALAIMHDPQLLILDEP
                     INGLDPIGIAEVRKFIRDLCTERGKTILISSHILSEIALLADDIGIIDHGILLEEESL
                     AQLEEKNSKYIHFAVSDAAHAARLLETQLNLKNFKVADNYNIMLYDTDVSVAEINRAF
                     ILNNIEVSESHLCEDTLEDYFKKVTGGEGIA"
     gene            10168..10938
                     /locus_tag="PC466_003921"
     CDS             10168..10938
                     /locus_tag="PC466_003921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2771224.1"
                     /translation="MKELLDIISCEFSKLKRLKFILISILGACLFPIPATILIAKDNL
                     PFEQLFKLVVNFGYFLLLPIVLSIVASQLFFIERDNDVLKNLATVPVPKGKLALAKLA
                     VLLFISLFYSVAGLGATIIGGFIVGIVEGVTVKLGMSIAFGIMFFVTVLPVVVLIVYF
                     NRSYIFSIILSFVYAIFNFSISLNIINFEPNNPLLSVLPAPVIMRWWMAFWGDPTGEY
                     TALRQPYLLSTPACVGILCLITIIAVLLICMIYKKQEN"
     gene            10948..11730
                     /locus_tag="PC466_003922"
     CDS             10948..11730
                     /locus_tag="PC466_003922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2771225.1"
                     /translation="MLDIITTEFQKIKRYNILWIGVVAVLFSALLAVFQVVSSHGSDP
                     LTYESFANGVIWNNFSLSFPFGITLIGGYLINREYTDQTLKNILTVPISLRKLLVGKL
                     IAVGGIAVLLSLFSFLCTFILGLLFCNINISVTLIVKSLVQILSVNLYCYVAVLPIIA
                     YFGRKQNAFLTGVGIAFVYGFCGVFVAGRNLTDFYPITAGLGLVGYNNGAGTVYQPLI
                     GAMTLIVILILTTILLVFTPNYDKVMTISKKKGIKHKKYSHK"
     gene            12107..12643
                     /locus_tag="PC466_003923"
     CDS             12107..12643
                     /locus_tag="PC466_003923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rubrerythrin family protein"
                     /protein_id="HDF2771226.1"
                     /translation="MNLKGTKTEKNLMAGFAGESEARNKYTYYASKARKEGYNQIAAI
                     FEETANNEKEHAKLWFKLLHDGMPSTEENLKDAAAGENYEWTDMYAKFAKEAREEGFD
                     KIAYLFEAVGKIEKEHEERYLKLLENLNEGKIFKRDEEVVWQCQNCGHVYVGTEAPEK
                     CPVCDHPKAYFNIKAENY"
     gene            12675..13064
                     /locus_tag="PC466_003924"
     CDS             12675..13064
                     /locus_tag="PC466_003924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HDF2771227.1"
                     /translation="MKFSKQRELILNEILNNPVHPTADYLYENLKKDNPNLSLGTVYR
                     NLAQLTEHGFIRKVSIPGYPDRFDGRIDNHYHIICEVCGEVYDLESEVLNNLQELISE
                     ETDIKITSYNISFKGICNNCKRCSQVG"
     gene            13101..13487
                     /locus_tag="PC466_003925"
     CDS             13101..13487
                     /locus_tag="PC466_003925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="desulfoferrodoxin"
                     /protein_id="HDF2771228.1"
                     /translation="MCSEQKFFICETCGNLVGMIQSGGVPIFCCGKPMKELVPNTTDA
                     AVEKHVPVIEVDGNNVTVKVSSTTHPMTKEHHIAWVYLMTEQGSQRKCLAVDGEPVVK
                     FALNDDDKVISAYAYCNLHGLWKAEL"
     gene            13614..15056
                     /locus_tag="PC466_003926"
     CDS             13614..15056
                     /locus_tag="PC466_003926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HDF2771229.1"
                     /translation="MSIYKCSVCGYIYDESKNDKTWDELSEDWECPVCTKGRSYFGKI
                     STVYYEEDEKIAEDIVENESKLNTEKEGDLNYLSTYLRRDDEVEKHMDIIHEMAVTGK
                     SIIEPMRTKLPVISWDDILIMGAQLNPLPLNEHDEVNTTTIIGKKAKKPMIIENPVYI
                     SHMSFGALSKELKIALAKGAAQNKTAMCSGEGGILPEEKEASYKYIFEYVPNKYSVTE
                     ENLKNSDAIEIKIGQGTKPGMGGHLPGEKVTEEIAKVRNKPVGQDVISPSCFEEIQSK
                     EDLKKLIDELREVSEGRPIGVKISAGHIEKDMEFIAYAKPDFVTIDGRGGATGASPKL
                     LKDATSIPTIFALYRARKYIDTHGLDIDLVITGGLRISTDFAKAIAMGADAVAIASSA
                     LMAAACQQYRICGSGKCPVGVATQDEELRKRLHIENSANRVANFLNVSLEELKTFARI
                     SGHKDIHDLSVDDLYTVNSEISNYTNIQHV"
     gene            15353..16168
                     /locus_tag="PC466_003927"
     CDS             15353..16168
                     /locus_tag="PC466_003927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF2771230.1"
                     /translation="MERLKIQVLVDNNTYIDRYFVGEPAVSYYIEIDGNRILFDSGYS
                     DVFISNAEKLNIDLGNLTHVVFSHGHNDHTRGIQFLENRYDLSTVELISHPNCFIPRK
                     HGEKSIGAPFSAEEIKNIFMYNPKDKPFNLSKNCVFLGEIPSINNFEKRAKIGKCKIG
                     DLWEDDYVLDDSAIVCKTDKGIFIVTGCSHSGICNIVEYAKRVCGDDRVIGILGGFHL
                     FELNNRLDSTIQYLDKEEIRMLYPCHCVSFKVKAKMNEILNINEVGVGLTISI"
BASE COUNT         5973 a         2037 c         2997 g         5477 t
ORIGIN      
        1 tgaaatgatg aaaatatatt tgatttcata caaaaaagag tgcctcataa ctaaaaagtt
       61 cactttgaga cactccattt ttatatgtta gttgcattta aggtaaaata gaagtttaat
      121 catgttgaaa taactgaatt acatcttcta aatgattgta cattgatgta taacctaagt
      181 aagagtcttt actatcaaat gccatcatta tcttgttatg gtggctaatc atatccttaa
      241 gagaatttct atatttaaaa ccgaagtatt ggttagaaga aactgtttta ggtattaact
      301 cataatattt tataaaaatt ggattatgag aagctaaaat tatctctttg tgaaattgta
      361 agtcagcatc ataacattct tctatcaaac catgagaaac cttatccaat tcctctattg
      421 actttaggta agtatatttt attttttgaa gttctttaga tgtagcattt aaaattgcta
      481 gtttagtagc ttcactttcg ataagttgtc ttgctcttaa agattctaca taaaattctt
      541 gtatgttatg atttttatag atttcaccat catcaaatag gtcaactttt ttaaatcctt
      601 caactatagg acttgagtaa ggcacagctc taagtattcc ttccttacag agtatattta
      661 tggcatttct tacaggtatt ctacttatgt taaataggtc agcaatcttt ctctcacttg
      721 gtaatttact attaatttta aaagttccat ttagaatgtt taatttaata taatcaataa
      781 ttttttcagt ggcatttaag cttttcataa aaactcctaa acatataatt tttttatgat
      841 tgtattatat catagttaag agttaaatct acttttttat aatatgtata agacaggata
      901 gaggccaaaa tagctataat agccaagata aagtatccat attgtattga agtatattcc
      961 gatattttac caactatcat tggaaataca gacattccta tagcataaat tgcttgaaaa
     1021 aaacccattg cagtagattt ctgatgtttt ggtacatttt tcatagactc gctagtaagg
     1081 taagaaagga gtatacctgt agatatacct ggtagcactt gtagtacaaa tattatatta
     1141 atatttttta ttgttggaac taaaaagcaa taggctgaaa ctaaaataaa aactaaagga
     1201 atccaaaatt ttggcccata cttagtacaa aatttagtag aagcaaagcc agaagaagca
     1261 acagcacaca ccatgtaaga tatagaagat agacctatga gggtagaact agaacctaag
     1321 tttttaagaa tttgagtagt aaatgacatt gttgtagaca tttgaatacc ctgttgaatt
     1381 aatgccataa aggaaaaaaa tacaagtctt ttatctttgc agatagataa atatttttta
     1441 attgatattt tttcaggtat tttttttgaa ttatgatttt ttatatttaa ggctagaatc
     1501 gttccaataa ctgaagacaa tacactcatg atacataagg ctgtcattcc taatttttca
     1561 taaaataaag tactcataac aaatccaatc aacattccta gattgtttac caatattatc
     1621 gtactcgtag ctttttgttg atgttctgta gaaaaaaagt tggtatagtg aaccatgtaa
     1681 gaaatccaag ttgatgatga tattccagat aaaatgttag ctataagaaa accattgcct
     1741 ccaggagaaa agactcttat aagagatgct aaaccagcaa agaaaattcc agacagtata
     1801 aatattttat gtttatttat agaatcagca aatactccaa caggaatcct taataaacat
     1861 tgtgagattc catatgcacc tattattata ccaatcatat ttgtagatac attacatgca
     1921 cttaaatatg gattttggaa aggtatatat acatattgtg aaaaccagaa aaatgtaaca
     1981 atagaaagta aaagtaattt ttgattagat atttttttca tattatcctc catatggtat
     2041 ttttataatg caaataatat accatttaga ttttttaatc aagtactttc tctattaaaa
     2101 aaaatttaaa tatataatta ttatttacaa aaaaattata ctttatagtt gaattaagaa
     2161 aacgcttatg atactataaa gttaacaaat ttgaatatat aacagtagac gtgttactgg
     2221 taatgcaggc aagatcgaat caatttttat agattatcta tagagtacta tgggtataat
     2281 ctatttattt ggttcgattt ttttgtttaa ttggccataa aacaaaaagc ctatagttga
     2341 aaatggagga ttttttatgg attataaaaa tatagctcaa gaaattctac taaatgtagg
     2401 aggaaaagag aatgtaaatg aagtgactca ttgtatgaca agacttagat ttaaagtcaa
     2461 aagcgcttct aaagtgaata aggataaatt atctaaaact gaaggagtaa taactgttgt
     2521 tgagagtatg ggtcaaatac aagttgtaat tggaaataaa gtaaaaacag tatatgatga
     2581 ggttataaaa attgtacctc aatcaaatga cgtaggtaaa aagaatgaaa gtcaagaaaa
     2641 gcaaagtata attaattcta tattatcagc agtagctggt atatttacac ctacaatacc
     2701 tgctatagca ggggttggta tgattaaagg tattttatca gttcttgcta tgtattatat
     2761 gaataaaaat ggagtagata taaaagaaac gcaaagttat attatcttaa atgccatggc
     2821 cgattctata ttctatttta tgcctattat actaggatat actgcggcta aagtatttaa
     2881 tgcaaataaa ataatatcta tggtattagg agctacactt tgttatccaa cttttactgc
     2941 tttgatggca ggtgaagaat ctgttagatt tttaggattg gcagtaacaa aagctacgta
     3001 tacatcatct gttattccaa taattattgc tatatgggct ctttcatacg ttgaaaaagt
     3061 attagaaaag tatatacctg aggtaattaa aataataatg gttccaactt tatcattggt
     3121 tgtaatgtta cctgcaacat tatttttatt tggaccaatc ggaatttata taggaaatgt
     3181 cataaacttt tcttataagt atatttatga attaagccca gcgttgtgtg gagcatttgt
     3241 aggtgggtta tggtgtgtgt tggttatatt tggtgctcat agagcattat taccaatagg
     3301 tataagtgat gttgctcaaa caggaagaca gaatttattg gcatttgcag gagctgcaaa
     3361 cttttcacaa gcaggggctg ctctaggagt attctttaaa actaaaaatc aaggactaaa
     3421 aacaatttct atgtctgcaa ctataacagc tttatttggt ataactgaac ctgcaatata
     3481 cggtgccaat cttagattaa aaaaacctat ggtatgtgcc gtaatatgtg gtgcatttgg
     3541 aggtgcgata atgggaatgg gtggagctta tggtaatgca tttgcaaacc aaggtgtttt
     3601 aactatacct gtatatgctg aagcaggtgc attaggtttc ttaagttatc taggtggttg
     3661 tgctatagca ttttttggtt cagctatttc aacttatcta gttggatttg aagatttgga
     3721 agagtcttct aataaggaaa attcatttat aaaagtagaa acgaaggatg gtgttattga
     3781 tataacttca cctgtagagg gcgaatgtat agaattgtca gaagtaaagg atgatgtatt
     3841 tgcttcaaaa gctatgggag aaggtatagc tgtgttacct acaaaaggag taataacagc
     3901 ccctactgat tgtgaagtag cttctttatt tccaacatta catgcaatag gattaaaatt
     3961 agataatgga gcagaaatgt taatacatgt tggaatcaat acagtagagt taaatggtaa
     4021 atactttaca aaacatgtta atcaaggaga tttagtgaaa aaaggtgata aacttatatc
     4081 gtttgatata gataaaataa aaaaggctgg ttatgatgta actacgccag ttatagtaaa
     4141 caatacattt gattttgggc aagtagtttc ttgtaaatct agttatgttt caaccaatga
     4201 taatataatt tcattagtat tagctggtaa ttaagttaat ttgactagag ataagtaaat
     4261 tgatttaaaa ggaaataagt aaatcaacaa ttaaatacat ctaaaagtaa gtttattgca
     4321 atgaattgtt aaagaaaata attaatatgg agtaaagcta ttgcaatgaa gtaacaaaga
     4381 aaataattaa tatagagtaa gtttattgta atgaattgtt aaagaaaata attaatatag
     4441 ggtaaatcta tctcaatgaa ataacaaaga aaagagttaa tatagagtga acttattgca
     4501 atgaatcaac aaaaaaaata atcaatataa aaaggagaaa tatttatgaa tacaggattt
     4561 ccaaaagact ttttatgggg agcatcatct tctgcatttc aagtggaagg agcttgggat
     4621 aaagacaata aaggaaaaac cgtagccgac tataattctt ttaaaaagtc tcatttacag
     4681 gcagatacta aagttgcatc agacttttac cataattatg aagaagatat tgaattaatg
     4741 aaagaattag ggatgaaaac atatcgtttt tcaatttcat gggcaaggat aataccagat
     4801 ggtgaaggag agataaacca gaaaggttta gacttttata ataagataat agacaaacta
     4861 atagagtgtg atattgagcc attcgtaact ttataccatt ttgaccttcc atttaaatta
     4921 gtagagaaat ataatggttg ggaaagtaga gaaactgtct atgcttttga aagatttgct
     4981 aaaatatgct ttaagcattt tggagatagg gtaaagtatt ggcaacctca taatgaacag
     5041 aatttaattg ttagagtgga ggagagaatt aatatatatg atgaaacaga ttcatggaag
     5101 atagataaaa tgcgtgctca gatggattat aatctttgct tagcacatgc attagcagtc
     5161 aatgcatgtc atgagatgat aaaagaaagt aaaattggag cagcagtatc atcatctgta
     5221 acatatcctc ttacttctaa gccagaagat gtatatgcag ctagaatgaa tgataatttt
     5281 aaagtgtact atatgcttga tatgcatcat tatggagaat atccagggta ttatatgaag
     5341 tatcttgaaa aaagaaatac agttcctcac atggaagatg gggataaaga gatacttaaa
     5401 aaagctaaaa tggattttat agctgtaaat tattatagga caaattgtgc agaagcttta
     5461 cctgaagatt cacaacatcc atttggatta agagaaggaa ctgttgattt tagtatgtat
     5521 ggactattta aaatgtcaat gaatcctaac ttagaggctt ctgagtatgg agcagcaata
     5581 gacccatcag gtcttagagt tgccttaaat gaatattggc aaagatatca cttacctgtt
     5641 ataataacag aaaatggtct aggagctaaa gatatattag aagatggaaa aattcatgat
     5701 gactatcgta tagactattt aagaagtcat ataaatgcat gtaaactagc tattgaagat
     5761 ggtgtagaga tgattggata ttgtccatgg tcatttacag accttttaag ttcttctcaa
     5821 ggttttaata agcgttatgg acttgtttat ataaatagaa ctgaccatga agttttagat
     5881 ttaaaaagaa tcaagaaaga tagtttttac tggtataaag aagttataga gaacaatgga
     5941 atagtaaaat aaacataaat atatattgag ggttttagta tgtacattac aaaggtatta
     6001 aataattcgt tgctacttgc aaaggatgat aatgatgaag aaataatatt gatggggaaa
     6061 ggcattggcc ataattataa ggccgggtct gagttaaata aaaaagatat agaaaagatt
     6121 tttgttcttc atgatgaaaa tataaaaaag agtattatac aattggcaac agaaatagat
     6181 gcagaatatt ttggtatagc tcaaatgata attgcatatg gaatagaaaa atataactta
     6241 aaacttatga accatatata tttggcctta actgaccaca ttgcctttgc agtgagacgc
     6301 tttaaagaag gtataatgat tgaaaatcac tatttgttcg aaatcaagga atttaatcca
     6361 aaagagtatg atataggaaa atatgctatt actgttttta aggaggttct tggtttagac
     6421 ctaccagaag aagagattgg taatatagca ggccatttta taaatgcaca acaagataat
     6481 ccttatagtg atagaaataa gagaagtgct aaaattgtaa atgctatttt gcaaatagtt
     6541 cattatcact tttctattgt atataataaa gagtcatttt attataggag atttgtaatg
     6601 catctaaagg ccttttcaca aagatttctg gctaatgaac catcaagaga aaaaatagat
     6661 tttatatatg agcaagttca aaaaaattgt aaggaagagt atgaatgtgt gaaaaaggta
     6721 ggagcttata tgtataagga atactccaga gaattaccaa gacaagagga gttatatttg
     6781 atgattcata ttcataagat tttaggagaa ttatgcgaaa atagttagaa tatcttaata
     6841 tgctagtaat attataaaaa attaaaaatt aactacactt taaatatgaa caattgcatt
     6901 acttaagggg gttgtcttaa aattgatttt tttaattaaa tttgaagctc aactcctttt
     6961 ttaaaccttt atatcattac aactttaatg tttatacgcc tgtactttag atgtatatct
     7021 actttttaca tttctcaaca tgcaaaccta ccattttttg cagtatgtta attgaaataa
     7081 accattgagt taaccctaaa tttattctgg acttatagga atagttccaa agatacttta
     7141 aaatattttc tggaataatt gcttatttca catatgtttt attgtgatgt tttgatttaa
     7201 taaattcttc aactctgtat atagtaaatg tattatcatg tttgttttat tcaagcacac
     7261 ttataatacg cttgattttt tcacaatgat gaaatatact aatgggtgtt ataggtataa
     7321 gaatcgaatt acacttgaag aagtaagtga taaatgagat ataaatcctc atatgataaa
     7381 ctactatttc attgaggaac atattctaag tgatgtcaag atactacaat atgactaaat
     7441 tcctagtgat aaaaaagtct acgaatgagt gtagaaaggg gaactaagat gaataaagtt
     7501 ttaattatag atgatgataa agatctttgt attttgttaa aaaagagtat ttcaattgaa
     7561 cagattgaag caaactattg ccattctggg agagatggac tggttgaact ttcaaaacaa
     7621 gattatcagt tagtagttct agacgtgatg atgccaggta tggatggttt tgaaactatg
     7681 gaacaaatac gaaaatatag cagtattccc atcttaatgc tgacatcaaa aagcgataat
     7741 tacagcaaag tgcatggatt gcgagctggt gcagatgact atctaaccaa accatttgaa
     7801 attacagaat ttactgctcg tgtactgtct ttaatccgac gttacacccg ttttaatcca
     7861 aaaaatgagg aaccacagca actttctttc aaaggtttgt tgattgacct tgaccagcat
     7921 acagtgacta ccaatggcga acctatgttg cttccaccca aggaatttgg tgtgcttctt
     7981 tactgtgcaa ggcatcaggg taagattttg acaaaacagc agatttatga agctgtgtgg
     8041 ggtgagccat atgtatatga tgacagcaat atcatggcta ttatcagtcg cctaagaaaa
     8101 aaaattgaac tagacccatc atctcccatc tatttgcaaa caataaaagg aattgggtat
     8161 caattcaaca cggaggtatg aaaatggatg aacaaacgat aattcttttc ttattcttgc
     8221 tgtcgattgg tctacttttt ctttccatat ttgctttttc caagcttggg catattcaca
     8281 aacgcctaaa agatatagag gagatactgg ctgatgtaca aattggaaac gaaaatcgca
     8341 aaatactaat taagccatgt gatgttatgg ctccattggt ttatcagctt aatgagattg
     8401 tctacgatta tgaaaataag ttactttctc tgaaaaagtc ggataaagct agcaaacaac
     8461 ttatgacaag tctatctcat gatgttcgta caccattaac aactctgatt ggttatctgg
     8521 atgctgtaca cagtggtata gttatcggac aagaacggga ggaatacctt gaaatcgcta
     8581 ggcgtagagc ctacgacctc aaggattaca ttgatgttct ttttgactgg tttcggttga
     8641 actctgatga atttacgctg tcaatagaat ctgtggaaat tgcagagttg tcacgcaata
     8701 ttttgaaaga ctggattcct atattccatg aaaagaaact gaattttgaa attgatattc
     8761 cagaaaatcg actaatggta aatctcgacc cagatggata ttcccgtgtg gttaataatc
     8821 tggttcaaaa tgttcttgct cacagtaagg ctcggcaaat caagattacc atgagtgagg
     8881 attccagaat ggtattactc cgtgttgatg atgatggtgt tgggattgcc agagaaaatt
     8941 taccacatat ttttgagcga ctgtataagt gtgataaagg acgttcagaa aaaggaagtg
     9001 gtcttggtct atctattgtc agtcaaatgg tggagcgaat gggtggtcag atttccgtag
     9061 aaagtgagat tggaaagtat accgtattta cagtgagctt accattaata taaaattgtt
     9121 tttcccccat gtgacatgta tacacagggg gattttttgt aagttataaa gttgcaaggt
     9181 taatacaagg ttgttgcaag gttaatgtaa gattgaggtg gtatgatagc tttaataaac
     9241 aaaggaggat tttattattt atgaataatt taattattga aacaaaaaat ctcactaagc
     9301 aatatggtgc tcaaaagagc gtttctaatt tgaatattca cgttcagaaa ggtcgcattt
     9361 acggattgct aggaagaaac ggtgcgggta agacgacaac tatgaaaatg ttattgggtc
     9421 taacaaaacc aactactgga gaaattaaaa tatttggtca ggacattcac aataacgaga
     9481 agaagcttct tcctcgaatt ggatgtttga ttgaatcacc agggttttat cctaatctga
     9541 caggaacaga aaatctcaaa atctttgcaa ggcttagagg aataccaaaa aaaaatgcag
     9601 tagaatcagc actggatgta gtcggtttgc caaacaatga caaaaagtta ttttctcaat
     9661 actctcttgg tatgaaacag aggttggcga ttgctcttgc cattatgcat gacccacaac
     9721 tgttgatttt ggacgagcct atcaatggac ttgatcctat tggtattgca gaagtaagaa
     9781 agtttattcg tgatctctgc acagaacgag gtaaaactat tttgatttcc agtcacattc
     9841 tttctgaaat tgccttgttg gcagatgaca ttggtattat tgaccatggt attttgttgg
     9901 aggaagaaag tcttgcccaa ttagaagaaa aaaacagtaa atacatacat tttgctgtat
     9961 ctgatgcagc acatgcagca aggcttctgg aaacccaact taacctgaaa aatttcaaag
    10021 tagcagataa ttacaatatt atgctatatg atacagatgt ttctgttgca gaaataaatc
    10081 gtgctttcat tctaaacaac attgaggtat cagaatctca tttatgcgaa gatactcttg
    10141 aagattactt caagaaagta acagggggtg aaggaattgc ttgatataat ttcatgtgaa
    10201 ttttcaaaac tcaagcggtt aaaatttata ctgatttcta ttttaggtgc ttgcttattt
    10261 ccaattcccg caacaatttt gattgcaaag gacaacttgc cctttgagca attgttcaaa
    10321 ttagttgtca attttggata ttttttgcta ttaccaattg tattaagtat tgttgctagc
    10381 caactatttt ttatagaaag agataacgat gtattaaaaa atcttgcaac agtgccagtg
    10441 ccaaaaggaa aactggctct ggcaaaattg gctgtgttgc tgtttatatc attgttctac
    10501 tccgttgcag ggttaggagc tactatcatt ggaggtttca ttgttggaat agtagagggg
    10561 gttactgtaa aattaggaat gagcattgct tttggaatta tgttttttgt tactgtactt
    10621 cctgttgtgg tactcattgt atatttcaat cgcagctata ttttttctat tatactttct
    10681 tttgtatatg ctattttcaa ttttagtata tccttaaata ttatcaattt tgaaccaaat
    10741 aacccactat taagcgtatt acctgctcct gttataatgc gttggtggat ggcattttgg
    10801 ggagatccca ctggcgaata cacggcactt agacagccat atttgctctc aactcctgct
    10861 tgtgtaggta ttttatgttt gataaccatt atagcagtcc tgctgatttg tatgatatac
    10921 aaaaagcagg agaattagga ggtatctatg cttgatataa ttactacaga atttcaaaaa
    10981 ataaaaagat ataatattct atggattggt gttgttgctg ttctgttttc agcactattg
    11041 gcagtttttc aggttgtaag ttcacacggc agtgaccctc taacgtatga gagctttgca
    11101 aacggagtta tctggaataa tttcagtctt agttttccat ttgggattac acttattgga
    11161 ggatatctta ttaaccgtga atatacagac caaaccttaa aaaacatcct aactgttcct
    11221 atttcattac gcaaattgct agtgggaaaa ttaattgcgg ttggaggaat tgctgtattg
    11281 ttaagtcttt tcagcttctt atgcacattt attttggggt tgttattttg caatatcaat
    11341 atatctgtta cactcattgt aaaatcctta gttcagattt tgtctgttaa tctgtattgt
    11401 tatgttgctg ttttgccgat tattgcttat tttggtcgta aacaaaatgc atttctgacg
    11461 ggtgtaggga ttgcatttgt atacgggttt tgtggtgtgt ttgttgctgg aagaaatctg
    11521 acagactttt atccaatcac agcaggtctt ggtctagttg gatacaacaa tggtgctggt
    11581 actgtttatc agccacttat cggtgctatg actttgattg taattctaat cttgacaact
    11641 attctacttg tatttacacc taattatgat aaagttatga ccatatctaa gaaaaaaggg
    11701 ataaagcata aaaagtattc tcataaataa cataaatatt gtttctatta tttaagttgc
    11761 tagacagtga aaagaaaaaa tctgtcgtac agtggctata tgctcatgta ttcaagaagc
    11821 tacagttttg atttttcata actgtagctt ctttttgtat ttattaaatc acggctatca
    11881 taatacttgc aataggtata gcgacaagag agagtactgt catgtgtgtt ttatatatta
    11941 cattaagtat attctaaaat atatgtttta aataatatat ttgaaaatag gaatatttaa
    12001 ataaaaaaaa taatattata tatagttgac aaaaattggc aaatgatata atatataaat
    12061 atagaaatag taatcattac tattattaaa aagggaggaa ttaattatga acttaaaagg
    12121 aactaaaaca gaaaagaatt taatggcagg atttgcagga gagtcagaag caagaaataa
    12181 atatacatac tacgcttcaa aagcaagaaa agaaggttat aatcaaatag ctgctatatt
    12241 tgaagaaact gctaacaatg aaaaggaaca tgctaaatta tggtttaaac ttttacatga
    12301 tggtatgcct tcaacagagg aaaatttaaa ggatgcagca gcaggtgaaa actatgaatg
    12361 gactgatatg tatgcaaaat ttgctaaaga agctagagaa gaaggatttg acaagatagc
    12421 ttatttattt gaagctgttg gaaaaataga gaaagagcat gaagaaagat acttaaagct
    12481 tttagaaaac ttaaatgaag gaaaaatatt taaaagagat gaagaagttg tttggcaatg
    12541 tcaaaactgt ggtcatgtgt atgtaggtac tgaagcacca gaaaaatgcc cagtatgtga
    12601 ccatccaaaa gcgtatttca atataaaagc tgaaaattat taaaaattat cattattaaa
    12661 aaggaatgtt aactatgaaa ttttctaaac aacgagaact gattttaaat gaaatattaa
    12721 ataatccggt tcatcctact gcggattacc tatatgaaaa cttaaaaaaa gataatccaa
    12781 atttaagctt aggaactgtt tatagaaatt tagctcagct aacggaacat ggctttataa
    12841 gaaaggttag tattccaggg tatccagata gatttgatgg tcgaatagat aatcactatc
    12901 atatcatatg tgaagtatgt ggagaggtat acgatttaga atccgaagtt cttaataatt
    12961 tacaagaatt aatatctgag gagacagaca taaaaataac atcttataac ataagtttta
    13021 aagggatttg taataattgt aaaaggtgta gccaagtagg ttagttttca aattctaaaa
    13081 ataattaatg aggtgagttt atgtgtagtg aacaaaaatt ttttatatgt gagacttgtg
    13141 gaaaccttgt aggaatgata caaagtggtg gtgtacctat tttctgttgt ggaaaaccta
    13201 tgaaggaact tgttcctaat acaacagatg cagcagttga aaaacatgta cctgtaattg
    13261 aagtggatgg aaataatgtt actgttaaag taagtagcac aactcatcca atgactaaag
    13321 aacatcatat agcatgggtg tatcttatga ctgaacaagg tagtcaacgc aaatgtctag
    13381 cagtagatgg agaacctgta gttaaatttg ctttgaatga tgatgataaa gtgatttctg
    13441 cctatgctta ctgtaattta catggattat ggaaggctga actgtaatat ttaaataaat
    13501 tgagtcaaag aggaggctat aaatgtattt tcatacaaat agcctcctat aaatttatat
    13561 aaattcaagt tttaattttg tttaatgtca atataatata aggagaaaat aatatgtcaa
    13621 tttataaatg tagtgtttgt ggatatattt atgatgaatc taagaatgat aaaacatggg
    13681 atgaattaag tgaagattgg gaatgccctg tatgtacaaa aggtcgtagt tattttggaa
    13741 agataagcac tgtttactat gaagaagatg aaaagatagc agaagacata gttgaaaatg
    13801 aatctaaatt aaatactgaa aaagagggag atttaaatta cttaagtaca tatttaagaa
    13861 gagatgatga agttgagaaa catatggata taattcacga aatggctgtt acaggaaaat
    13921 ctataataga acctatgaga actaaactac cagtaatttc ttgggatgat attttaatta
    13981 tgggtgctca attaaatcca ttacctttaa atgagcatga tgaagtaaat acaacaacaa
    14041 taataggaaa aaaagcaaag aaacctatga ttatagaaaa tccagtttat atttcccaca
    14101 tgtcatttgg agctttgtct aaagaactaa aaatagcttt agcaaagggt gcagcccaaa
    14161 ataagacagc tatgtgtagt ggtgaaggag gtatattacc agaagagaag gaagcttcat
    14221 acaagtatat ttttgagtat gtaccaaata aatatagtgt aactgaagaa aatcttaaaa
    14281 attctgatgc tatagagata aaaattggtc aaggaacaaa acctggtatg ggaggtcatc
    14341 ttcctggcga aaaagtaact gaagaaatag caaaagtaag aaataagcct gtaggtcaag
    14401 atgtaataag tccatcttgt tttgaggaaa tacaatccaa agaggattta aagaaactta
    14461 tagatgaact tagagaagtt tcagaagggc gtccaatagg tgttaaaatt tcagcaggtc
    14521 atattgaaaa agatatggaa tttatagctt atgctaaacc tgattttgta actattgatg
    14581 gtcgtggtgg agctactgga gcaagtccaa agttgcttaa agatgcaact tcaattccaa
    14641 caatatttgc tctttatcgt gctagaaaat acatagatac acatggatta gatatagatt
    14701 tggttataac aggtgggctt cgtatatcta ctgattttgc taaggcaatt gctatggggg
    14761 ctgatgcagt tgctattgca agttctgctc ttatggcagc ggcgtgtcaa caatatcgta
    14821 tatgtggttc tggtaagtgt cctgtaggag tagctactca ggatgaggaa ttgagaaaaa
    14881 gattacatat agaaaatagt gctaatagag tggcaaactt tttaaatgta agtttagaag
    14941 aacttaagac ttttgctaga atttctggtc ataaagatat acatgattta agtgttgatg
    15001 atttatatac tgttaactct gaaatatcaa attatacaaa catacagcat gtatagattg
    15061 aagtttgaaa ctattagatt ttagatagct ataaaagtaa atgataaata tattttataa
    15121 aagagagtgt cttaaaatga actttttagt tcataagtca ctcttttttg tatgaagcca
    15181 aatatattta tcattttagc aatgaaaaag aatcttatct ctttattttg agatagactc
    15241 cttctattta tgaaaattaa agatattaaa ttgtaaaata ttctgtgatg tcgtactatt
    15301 aaactaaaga ttctgtactt taaagtaaat aaaaatttaa ggagtgctta ttatggaaag
    15361 attgaagata caagttttag ttgacaataa tacttatatt gatagatact ttgttggaga
    15421 accagcagta agctattata ttgagattga tggaaatagg attttgtttg attcgggata
    15481 ttcagatgta ttcatatcaa acgctgaaaa attaaatata gatttaggaa atttaactca
    15541 tgttgttttt tctcatggac ataatgacca tacaagaggt atccagtttt tagaaaatag
    15601 gtatgattta tctacagttg aacttatttc acatcctaac tgttttatac ctagaaaaca
    15661 tggagagaaa agcataggag ctccattttc tgctgaggaa attaaaaata tttttatgta
    15721 taatcctaag gataagccat ttaatctaag taagaattgt gtgtttttag gtgaaatacc
    15781 ttctataaat aattttgaaa aaagagctaa aattggtaaa tgtaaaatag gagatttgtg
    15841 ggaagatgat tatgttttag atgattctgc tatagtttgt aaaactgata aaggtatttt
    15901 tattgttaca ggatgttctc atagtggaat ttgtaatata gtagagtatg ctaaaagggt
    15961 atgtggagat gatagagtta ttggtatact aggtggtttt catctttttg aattgaataa
    16021 taggttagat agtacaatac aatatttgga taaagaagaa ataagaatgt tgtacccttg
    16081 tcactgtgtt tcttttaagg taaaagctaa gatgaatgaa atattgaata taaatgaagt
    16141 tggagtaggg ctgaccataa gtatatagta tttgaaagta tataagattt aagttgaagg
    16201 ttaaaaagat attttctata taaagtatct tttttgttac gtttatttta agagaaatca
    16261 atatactttt atatgaaata ttgtaaaaaa atttattttt aatgagaata tattttcatt
    16321 aataaacaat tttattatgt attaataatg ctagaataaa tataaataaa tcaaagttac
    16381 ttacattaaa gtatattttt tcacaaaata tattgattta ttcttttaaa gtttgataat
    16441 tccaatgaat gtaataaaag aagggatttt atactataca atta
//
LOCUS       DAMJYN010000265        11229 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.guided.108, whole genome shotgun sequence.
ACCESSION   DAMJYN010000265 DAMJYN010000000
VERSION     DAMJYN010000265.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11229)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11229)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11229
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.guided.108"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            247..864
                     /locus_tag="PC466_003928"
     CDS             247..864
                     /locus_tag="PC466_003928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HDF2771231.1"
                     /translation="MCKKTYLLVVSILIAGLLTACSGSPTKDSGQAQDNTKKEANASN
                     NALKDEKNNENLMEQDFKVPYTDAINIFKDKYKDADIVDLSLERDLNKFVYTVEGVDD
                     NNEYKMKIDANTKDVLEDKTEKLDSEDLNGVARKEKLDLNDIITPQQAMEIALKEQNG
                     MVKEWSLDKDLDVTFYKIRIDKDKNEYDIKVDSKKGTVLKVEKED"
     gene            972..3503
                     /locus_tag="PC466_003929"
     CDS             972..3503
                     /locus_tag="PC466_003929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HDF2771232.1"
                     /translation="MSLKSLKIKENLYWVGSLDPDLRVFDIIMYTPYGTTYNSYVLKG
                     TEKTVLFETVKDKHFDNYIERLNDLNIDFEKIDYIVVSHTEPDHAGSVEKLLDLAKNA
                     KVVASETAIKYLKEIVNKDFEYVAVTDGDTLSIGDKTLEFFSVPMLHWPDTIYTYIKE
                     DKTLVTCDSFGSHYSNDKIVNTLDENEEKDYLDALRYYYDCIMGPFKPSMVTAIEKIK
                     DLDIDTVCPGHGPVLTENPRKIIDLYYNWSVKEQIKLEKEVTICYVSAHGYTKIMAEA
                     IKAYIEKNSNYKVNLFDVIEHKQEDILAKIAVSQGVLFGTPTILGDALKPIWDILISL
                     NPVLHGGKVASVFGSYGWSGEGIENAMERISQLRMTAVKPFAVNFKPSNEEIDKLHSY
                     TGKFLDKLNSTFGSKKKTKKFKCVICNEVFEGDSAPSVCPVCGAKEDQFIEVEEDEVT
                     FRKDTDEYFVIVGNGAAGFYAADAIRKRNKTCKITMISNEDELTYYRPALSDGINEEL
                     GSDFYMEDKDWYDKNNIVVILGTNVDKLDEVNKTIIVNDGAIKFDKLVIATGSRNFIP
                     PIKGHDLENVFTLRNIKDLYSVKEALEKSKKVVVIGGGLLGLEAAWEFRLKGLEVVVV
                     EAMDSILSKQLDKEGSKILEQCVRDTGIDVRLGVAVDGIEGDGKAQKVVFKDGDSVDC
                     DMVVFSIGVRANTQMVQDTSVKIDRGIVVDKTLQTNVKDIYACGDVAQVGNISLAIWP
                     SSVEMGKIAGANASGDNLTFESEVYPVSLDAMNVKVFSIGNIQNFDKEISSKDEGQRI
                     YKKLFMKDGSLVGAILINDLSCTVKLIRLISEKGDFEDIMKADIL"
     gene            3937..4638
                     /gene="vanR"
                     /locus_tag="PC466_003930"
     CDS             3937..4638
                     /gene="vanR"
                     /locus_tag="PC466_003930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanR-ABDEGLN family response regulator
                     transcription factor"
                     /protein_id="HDF2771233.1"
                     /translation="MNENILIVDDKKEIADLIEVYLKNEGFTVYKFYTGKEALECIES
                     KDLDMAILDIMLPDIDGFHICQKIREKYYYPIIMLTAKIEDIDKIMGLTIGADDYITK
                     PFNPLEVVARVKTQLRRYMRYNNSYEQQSIIVNEYDIKGLIINKETHKCSLFGKEVAL
                     TPIEFSILWYLCEHQGKVVPSEELFEAVWGEKYLDNNNTVMAHIGRLREKIHEPSKNP
                     KFIKTVWGVGYTIEK"
     gene            4688..5770
                     /locus_tag="PC466_003931"
     CDS             4688..5770
                     /locus_tag="PC466_003931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDF2771234.1"
                     /translation="MRTALMAFIAIIFIWILYSFILYGKFSIWIVSFFENAFRMEYKA
                     ALNLYQQIFRNSMELFMILAMVIVFFIIFRVYLNWFTKYFSEINQGIDSLIKEDVGEV
                     ALSPELLAIEKKINSIKHILEQRKFETQMAEQRKNELIVYLAHDLKTPLTSVIGYLTL
                     LRDESQISEELRKKYLSISLDKAERLEDLINEFFEITRFNLSNISLEYSTVSLTRMLE
                     QLTYEFKPTLMSKNLKYTLNVTPNMMIRCDVNKMQRVFDNLLRNAVYYSFEDTTIEIT
                     AVQEDDYIKLKFINHSNTIPEEKLERIFEQFYRLDTSRNSNSGRAGLGLAIAKEIVEL
                     HNGTITAHSENNIITFKVIIPIVGNL"
     gene            6027..7127
                     /gene="vanG"
                     /locus_tag="PC466_003932"
     CDS             6027..7127
                     /gene="vanG"
                     /locus_tag="PC466_003932"
                     /EC_number="6.3.2.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-serine ligase VanG"
                     /protein_id="HDF2771235.1"
                     /translation="MNNKKIAVIFGGNSTEYDVSLQSAFAVLENLNTEKYDIIPIGIT
                     REGNWYHYIGDYNNIQNNTWFERDTDIIPVIVSQNRVKNGIIEFLIPDAVSQNHIPNS
                     AIESCENDIKYTKLDFVFPVLHGKNGEDGTVQGLFELAGIQVIGCGTLSSALCMDKDK
                     SHKLVHSEGIKVPKSILLKYSDKFNVAELSKDLTYPLFIKPVRAGSSFGISKIYKKEE
                     LQVAVDLAFEHDNEVIIEENIDGFEVGCAVLGNDDLLVGRVDEIELSKGFFDYTEKYT
                     LKSSKIHMPARIDLDCEKRIQETAKIIYRTLGCSGFARVDMFLTPSGEIIFNEVNTIP
                     GFTSHSRYPNMMKGIGLSFEEILDKIIEVYIK"
     gene            7124..7930
                     /locus_tag="PC466_003933"
     CDS             7124..7930
                     /locus_tag="PC466_003933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HDF2771236.1"
                     /translation="MMNNILLDKNKEDKMTNTILLTKDKVYDGNLILVNAFLPVKTSE
                     DIDLIPVDTRFPSILMKREATNILQNILKSICGINEIVPVSGYRTAEEQQDIYSSSLR
                     DNGKDFTKKFVALPNHSEHQTGLAIDLGLKKEVIDFICPEFPYNGICNEFRKAALHYG
                     FIERYQCKKEEITGISQEPWHFRYVGYPHSEIINKMNLALEEYIEYIKRFSYTNCLKI
                     EDKEKIIEIFYVPIHTKEEVRISIPEQCVYQISGNNKDGFIVTFWRNRKD"
     gene            7948..10086
                     /gene="vanT"
                     /locus_tag="PC466_003934"
     CDS             7948..10086
                     /gene="vanT"
                     /locus_tag="PC466_003934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine racemase VanT catalytic subunit"
                     /protein_id="HDF2771237.1"
                     /translation="MIRNKSYAGLDYFRIIAALLIIAIHTSPLLSYSKMADFVLTSII
                     ARIAVPFFFMLSGFFLISTYNYNCNKLKSFLKNVLFIYGIAIVIYIPLNIYTGYFSMN
                     NLVPNIIKDIVFDGTLYHLWYLPASIIGASIAYFLVKKLGLKYSLVITIVIYVIGMFG
                     DSYYGFLEKIPLLKNLYGYIFEVSDYTRNGIFFAPVFFILGGIISNKSNYMSTKNSLI
                     GFLISFLLMLCEGMFLHKLGVQRHDSMYIMLLPCMYFLFTALTFLKGSRARLLRTSSL
                     IIYIIHPMMIVVIRMFSKIFGIQTVLVDNSLIHYIVVSIASFIASIIIILILKPLKKD
                     LKGEHKVNTNRAWIEIDLNNLEHNVKMIQKAMPEDCELMAVVKANAYGHSAFEVATCA
                     NQIGVKAFAVATIDEGIDLRRYGILGEILILGYTNPIRAKELHKYNLTQSVIDLNHAI
                     SLNKQKYNIKSHIKIDTGMHRLGFDVNDVRSILKAFKLKYLDICGIFTHLCVSDSLKD
                     EDVDFTNKQIECFYKLIDFLLKKGIKIPKVHIQSSYGFFNYPNLKCNYVRIGIALYGI
                     LSSPNDTTKLQLDLRPVLSLKSQVILIRKIQKDDSFGYGRVFIASRDSVIAILSIGYA
                     DGIPRNLSCGKSYVIINGCRAAIVGRICMDQLAVDITDIPNVEVGNTAIIIGRDNLSE
                     LSASEVANNSCSISNELLSRVGRRLNVIKK"
     gene            10400..11020
                     /locus_tag="PC466_003935"
     CDS             10400..11020
                     /locus_tag="PC466_003935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HDF2771238.1"
                     /translation="MQYIQELLDLTQNYWVLATIIGLLSAFIESFIPALPLVAIVTAN
                     AAIQGLFIGCLLSWIGSGLGTTSLFLLISRFNDSKLFNKLRNSKTEKAISWMDKQGFK
                     LLFIAYACPFMPGCLVTIASAFGKKDLKDFVPAMLAGKFVMFIVISYVASDIEGFITS
                     PLKIASFILLVFLSWKIGNRVNKNLENHNYDFHHKKHHNDKDDKMI"
BASE COUNT         4262 a         1170 c         1990 g         3807 t
ORIGIN      
        1 tcaaaatgaa ctttttagtt catgaggcac tctttttgta cgaaataaaa tatattttta
       61 ttatttcaac aatgaaaaag atgcttgttt ctattttgag acagtataat ttttatgtaa
      121 ctttaatttt agtaaatata aagttttaaa attgataaaa taggaggaat ttttaatata
      181 aaagggtaaa taaagggttt agagggcata atatagaata aattaatata tttaaggagg
      241 atttttatgt gtaaaaaaac gtatttatta gtggtaagta tacttatagc aggtttatta
      301 actgcatgta gtgggagccc aactaaggat tcaggacaag cacaagataa tacaaaaaag
      361 gaggcaaatg cttcaaataa tgctttaaaa gatgaaaaaa ataatgaaaa tttaatggaa
      421 caagatttta aagtgccata cacagatgca ataaacatat ttaaagataa atacaaggat
      481 gctgatatag tagatttaag tcttgagaga gatttaaata aatttgttta tactgtggaa
      541 ggtgtagatg ataataatga atataagatg aaaattgatg ctaatacaaa agatgtatta
      601 gaagataaaa cagaaaagtt agattcagaa gatttaaatg gagttgctag aaaagaaaaa
      661 ttagatttaa atgacataat tacacctcaa caagctatgg aaattgcatt aaaagaacaa
      721 aatggaatgg ttaaagaatg gagtttagac aaagatttag atgttacttt ttataaaata
      781 agaatagata aagataaaaa tgaatatgac ataaaagtag attctaaaaa gggaactgta
      841 ttgaaggtag aaaaagaaga ttagaagatt taaactatct ttaaaataat ttcttttttg
      901 aataaatttt gtttaaaata taacaagcag ggtataaaga gactaaataa ctattttagg
      961 aggagtacgg tatgtcattg aaatcactaa aaataaaaga aaatttatat tgggtaggtt
     1021 cacttgaccc tgatttaaga gtatttgaca taattatgta tacaccttat ggaactactt
     1081 ataattcata tgtattaaaa ggaacagaaa aaacagtttt gtttgagaca gttaaagata
     1141 agcattttga caattatatt gaaagattaa atgatttaaa tatagatttt gaaaaaatag
     1201 actatattgt tgtaagtcat actgaaccag accatgcagg aagcgttgaa aagcttttgg
     1261 atttagctaa aaatgcaaaa gtagtagctt cagaaacagc aattaaatat cttaaggaaa
     1321 tcgtaaacaa agactttgaa tatgttgcag ttacagatgg agatacatta tcaattgggg
     1381 acaaaacttt agaatttttc tctgtaccta tgcttcattg gccagatact atatacacat
     1441 atataaaaga ggataaaact cttgtaacat gtgattcatt tggtagtcac tatagtaatg
     1501 ataagatagt aaatacactt gatgaaaatg aagaaaagga ttacttggat gctttaagat
     1561 actattatga ttgtataatg ggtccattta aaccatctat ggtaactgct atagaaaaga
     1621 taaaagattt agatatagat actgtatgtc caggtcatgg tccagtatta actgaaaatc
     1681 ctagaaaaat tatagacctt tattataact ggagtgtaaa ggaacaaata aagttagaaa
     1741 aagaagttac aatttgttat gtttctgcac atggatatac aaagattatg gcagaagcta
     1801 taaaagcata tattgaaaaa aatagcaact ataaagtaaa tttatttgat gtaatagagc
     1861 ataagcaaga agatattttg gcaaaaatag cagtatcaca aggtgtatta tttggaacac
     1921 caacaatatt aggagatgcg ttaaagccta tatgggatat attaatatcg ttaaacccag
     1981 ttcttcatgg tggaaaagtt gcttcagtat ttggttcata tggatggagt ggagaaggta
     2041 tagaaaatgc tatggagaga ataagtcagc ttagaatgac agcagtaaaa ccttttgctg
     2101 ttaactttaa accatcaaat gaagagattg ataaattaca ttcttataca ggtaaattcc
     2161 tagataagtt aaattctact tttggaagta aaaagaaaac taagaaattt aaatgtgtaa
     2221 tttgtaatga agtttttgaa ggtgatagtg ctcctagtgt atgccctgta tgtggagcta
     2281 aggaagacca atttatagaa gttgaagaag atgaagttac ttttagaaaa gatactgatg
     2341 aatatttcgt aatagtagga aatggagcag ctggttttta tgcagcagat gctataagaa
     2401 aaagaaataa aacttgtaag ataactatga tttctaatga agatgagttg acttactata
     2461 gacctgcact ttctgatggt ataaatgaag aacttggttc agatttctac atggaagata
     2521 aagattggta tgataaaaat aatatagtag taatattagg aacgaatgta gataaattag
     2581 atgaagtgaa taaaactatt atagtgaatg atggagctat taaatttgat aagcttgtaa
     2641 tagctacagg aagtagaaac tttataccac cgattaaggg ccatgattta gaaaatgtgt
     2701 ttactcttag aaatataaaa gatttatata gtgtaaaaga agcactagaa aaatctaaga
     2761 aagttgtagt gattggtggc ggtttattgg gacttgaagc tgcatgggaa tttagactaa
     2821 aaggattaga agtagtagta gttgaagcca tggatagcat actatcaaaa caacttgata
     2881 aagagggtag taaaatatta gaacaatgtg taagagatac aggaatagat gtaagattgg
     2941 gtgtagcagt tgatggtatt gaaggtgatg gaaaagctca aaaagttgta tttaaagatg
     3001 gagatagtgt tgactgtgat atggtagtat tttcaattgg tgtaagagca aacactcaaa
     3061 tggttcagga tacatctgta aaaattgata gaggtattgt tgtagataag acattacaga
     3121 caaatgttaa agatatatat gcttgtggag atgttgcaca agtgggaaat attagtttag
     3181 caatatggcc atcttcagta gaaatgggaa aaatagcagg agcaaatgca agtggagata
     3241 atttgacatt tgaaagtgaa gtatatccag tttcattaga tgcaatgaat gtaaaagtat
     3301 ttagtattgg taatatacaa aattttgata aagaaatttc atcaaaagat gaaggtcaaa
     3361 gaatatataa aaaattattt atgaaagatg gttcattagt tggagctata cttataaatg
     3421 atttaagctg tactgttaaa ttgataagat taatatctga aaaaggtgat tttgaggata
     3481 ttatgaaggc tgatatacta taatttaaat acattaaaat aaaaaggagt tgtctcaaaa
     3541 ttgatttttt tctaatcaaa ttttaaattc aactcctttt ttgaattttt atataaaata
     3601 acatggaaat tttagtaatg tctgtggtta catacatagg tttaattgtt ttttatatgg
     3661 attgtctctg gtataataaa ttgaattgtg tttgactgat agatattttt attgaaagtt
     3721 aatacctgtt atgcgataat aaggacgtgt taggggagtt tttataataa caattaatct
     3781 cagtttttgt gttccaatag tagcatcaac acattctgat gtagtagttc ttttcttata
     3841 aaaattagtt acaaatatgc ttgtaattat ttgatatgta aatttaccaa tattataaat
     3901 gatgacctcg ataataagga gagtgaaaaa taatctatga acgaaaatat tttgattgtg
     3961 gatgataaaa aagaaatagc agatttaatt gaagtatatt taaaaaatga aggttttaca
     4021 gtatacaagt tttatacagg taaggaagct ctagaatgta ttgaatctaa agatttggat
     4081 atggctattt tagatattat gcttcctgat attgatggat ttcatatttg ccagaaaatt
     4141 cgagaaaaat actattatcc tatcattatg ttaacagcta aaattgaaga tatagacaag
     4201 ataatgggtt taaccatagg tgctgatgat tatataacaa agccatttaa ccctttggaa
     4261 gttgttgcaa gagtaaagac acaattaaga agatatatgc gatataataa ttcttatgaa
     4321 caacagtcga taattgttaa tgagtatgat attaaaggat tgattatcaa taaagaaaca
     4381 cataaatgta gtttatttgg gaaagaagta gcattaacac cgattgaatt ttctattctt
     4441 tggtatttat gtgaacatca aggaaaagtg gttccttctg aagaattgtt tgaagctgta
     4501 tggggagaaa aatatcttga taataataac acagttatgg ctcatatagg gcgattacgt
     4561 gaaaaaattc atgaaccttc taaaaacccg aaatttataa aaactgtatg gggagtaggt
     4621 tatacaattg aaaagtaaaa atattaaagt caatcctgac tttactcaag tgagaaataa
     4681 aatttttatg agaacagctt taatggcatt tatagccatt attttcatat ggattttata
     4741 ttcttttata ttgtatggta agttttctat ctggatagta tcattctttg aaaatgcttt
     4801 tcgtatggaa tataaagctg cattgaattt atatcagcag attttccgta atagcatgga
     4861 gctcttcatg atactagcta tggtgattgt gttttttata atattccgtg tttatttaaa
     4921 ttggtttaca aaatatttta gtgaaataaa tcaaggtatt gactctctta tcaaagaaga
     4981 tgttggagaa gtggctttat ctccagagtt attggcaata gaaaagaaaa taaactcaat
     5041 taaacatata cttgaacaac gtaaatttga gacacaaatg gcagaacaac gtaagaatga
     5101 acttattgtt tatcttgcac atgatttaaa aacaccactt acatcagtta tagggtatct
     5161 gacactactt cgagatgaaa gtcagatttc tgaagaactg cgaaaaaaat atttatctat
     5221 ttcgttggat aaggcagagc gtcttgaaga tttaattaat gaattctttg aaattacaag
     5281 gtttaattta tcaaatatat cacttgaata cagtacagta agcttaactc gtatgcttga
     5341 acaactaaca tatgagttta aacctacttt gatgagtaag aatttaaaat atacactgaa
     5401 tgttacacca aatatgatga taaggtgtga tgttaataaa atgcaacgtg tatttgataa
     5461 cttattacga aatgctgttt attatagttt tgaagatact actattgaaa taacagctgt
     5521 acaggaggat gattatataa agcttaaatt tataaatcat agcaatacga ttccagagga
     5581 aaaacttgag cgtatttttg aacaatttta caggttggat acatctcgta attcaaacag
     5641 tggtagagct gggttgggac ttgctatagc taaagaaata gtggagcttc ataacgggac
     5701 aataacagct catagcgaga acaatataat tacctttaag gttattattc cgattgtagg
     5761 aaatttgtaa gaatttaagt ataaaaaaat aggaaattct ttaggataaa taaagagcac
     5821 tcttgttatt gatataatta ctgtatcaaa acaagagtgc ttttattttg atacagtaat
     5881 tatatcaata gaaaaatgtg aaaatatatt atgtggaaca gatgcaattg taagtgaagg
     5941 ttgattggat ttgaaataga aaaagtattt taacatgttt ctgtagattg tataaaaata
     6001 aataaatcaa caaaggagaa tcaaagatga ataataaaaa aattgcagtt atatttggtg
     6061 gaaactcaac agaatatgat gtatcattac aatcagcttt tgcagtactt gagaatttga
     6121 atacggaaaa atatgatatt ataccaattg gaattacaag ggagggtaat tggtatcatt
     6181 atattggaga ttataataat atccagaata acacttggtt tgaaagggat actgatataa
     6241 ttccagttat tgtttcgcag aaccgtgtca aaaatggtat tattgaattt ttaattcctg
     6301 atgctgtttc tcagaatcat attccaaata gtgctattga atcatgtgaa aatgatatta
     6361 aatacactaa acttgatttt gtatttcctg tattgcatgg aaaaaatgga gaagatggaa
     6421 cagtgcaggg gttatttgaa ttggcaggta tacaggttat tggatgtggt actctttctt
     6481 cagcattatg tatggacaaa gacaaatcac ataaacttgt tcattcagaa ggtattaaag
     6541 taccaaaatc aatattacta aaatactcag ataaatttaa tgtggctgaa ctgtcaaaag
     6601 acttaactta tccattattt ataaaacctg tgcgtgcagg ttcatcattt ggtattagta
     6661 aaatttataa aaaagaagag ttacaagtag cagtagactt ggcttttgaa catgataatg
     6721 aagtaataat tgaggaaaat attgatggtt ttgaggtagg gtgtgcagtt ttaggaaacg
     6781 atgacttact tgttggaaga gtagatgaaa tagaattgtc aaaaggattt tttgattata
     6841 cagaaaaata tacattgaaa agttcaaaaa ttcatatgcc agctagaatt gatttggatt
     6901 gtgagaaaag aatacaagag acagcaaaaa ttatttatag aactcttgga tgttctggat
     6961 ttgctagagt agatatgttt ttaactccat ctggtgaaat tatttttaat gaagtcaata
     7021 caattcctgg ctttacttct catagtcgtt atccgaatat gatgaaaggt attggactgt
     7081 cttttgaaga aatattggat aagataattg aggtgtacat aaaatgatga ataatatttt
     7141 attagataaa aataaagaag ataaaatgac aaatactatc ttattgacta aagataaagt
     7201 ttatgatggg aatctaattc tagtaaatgc ttttttacca gttaaaacat ctgaagatat
     7261 agatttaatt cctgtagata caaggtttcc aagtattctt atgaaacgtg aagctacaaa
     7321 tattttacaa aatattttaa aaagtatatg tggaataaat gaaatagtac ctgtaagtgg
     7381 atatcgtact gcagaggaac aacaagatat atattcaagc tctctgcgtg acaatggaaa
     7441 agactttact aaaaagtttg tagcacttcc aaatcacagt gaacatcaga cagggcttgc
     7501 tattgattta gggttgaaga aagaggttat agattttatc tgccctgaat ttccttataa
     7561 tggtatttgt aatgagttcc gtaaggcagc actacattat ggttttatag agcgttatca
     7621 gtgtaaaaaa gaagaaataa caggaatatc tcaagaacca tggcattttc gttatgtcgg
     7681 atatccacat tctgagatta tcaataaaat gaatctcgcc cttgaagaat atatagaata
     7741 tattaagaga ttttcgtata caaattgttt aaaaatagaa gataaagaaa aaattataga
     7801 aatcttttat gtgcctattc atactaaaga agaagtgaga atctctatac ctgaacaatg
     7861 tgtatatcaa atatcgggta acaataagga tggttttatt gtgacatttt ggagaaatag
     7921 aaaggactaa gaaatggagg aacaagaatg attaggaata aatcttatgc agggcttgat
     7981 tattttagga ttatagctgc attacttata attgcaattc atacatctcc attattatca
     8041 tatagtaaaa tggctgactt tgtgttaact agtataattg ctcgtattgc tgtgccattc
     8101 ttttttatgc tatcaggctt ttttctaatt tcaacatata attataattg taataaactg
     8161 aaatcttttc taaaaaatgt attatttatt tacgggatag ctattgtaat ttatattccc
     8221 ttaaatattt acactggata tttttccatg aataatttag tgcccaatat tattaaggac
     8281 attgtatttg atgggacttt atatcattta tggtatctac ctgcatcaat tattggtgca
     8341 agtattgcat actttcttgt aaaaaaacta ggtttaaagt actcattagt aatcactatt
     8401 gttatttatg taattggtat gtttggtgat agttattatg gttttttaga aaaaatacca
     8461 ctattaaaga atttatatgg gtatattttt gaagtatcag attatacacg aaatggtata
     8521 ttttttgcac ctgtattttt catacttggt ggaataatat ctaataaatc taattatatg
     8581 tcaactaaaa atagcttgat tggatttctt atatcattct tacttatgtt atgtgaggga
     8641 atgtttttac ataaactagg ggtacagcgt catgatagca tgtatattat gttattgcca
     8701 tgtatgtatt tcttatttac agccttaaca tttttaaaag gttctcgagc taggttattg
     8761 cgaacatcat cattaattat ttatattata catcctatga tgattgttgt tattcgtatg
     8821 ttttctaaaa tattcggaat acaaactgtc ttggttgaca atagccttat tcattatata
     8881 gtggtaagta tagcatcttt tatagcttct ataattatta tattgattct taaacctcta
     8941 aaaaaagact tgaaaggaga acataaggta aataccaata gagcttggat tgaaattgat
     9001 ttaaataatt tggaacataa tgtaaagatg atacaaaaag ctatgccaga agattgtgaa
     9061 ttgatggcag ttgtaaaagc taatgcctat ggtcatagtg cttttgaagt agcgacttgt
     9121 gcaaaccaaa taggtgtaaa agcatttgca gtagcaacaa tagatgaggg gattgattta
     9181 cgtcgatatg gaatactagg agaaatattg attcttggat atactaaccc aataagggca
     9241 aaggaacttc ataaatacaa tcttacacag agtgttattg accttaatca tgctatctct
     9301 ttaaacaaac agaaatacaa cataaaatca cacattaaaa ttgatacagg tatgcacaga
     9361 ctgggttttg atgttaatga tgtgaggtca attttaaagg catttaaatt aaaatactta
     9421 gatatatgtg gcatatttac acacttgtgt gtttcagata gtctgaaaga tgaagatgta
     9481 gactttacaa ataaacaaat tgaatgtttt tataagttaa ttgattttct gttaaaaaaa
     9541 ggtataaaaa ttcctaaagt acatattcaa agtagttatg gtttttttaa ttatcccaat
     9601 cttaagtgta attatgtaag aattggaatt gcattatacg ggatattaag ttctccaaat
     9661 gatacgacta aattgcaact tgatttacga cctgttttat ccttaaaatc acaagtaatt
     9721 cttattagaa aaatacaaaa agatgatagt tttggatatg gaagagtctt tattgcaagc
     9781 agagatagcg taattgctat attatctatt ggctatgccg atggtatacc tagaaattta
     9841 tcctgtggaa aaagttacgt aataataaat ggttgtagag cagcaatagt gggtcgaatt
     9901 tgcatggacc aacttgctgt tgatattaca gatataccta atgtagaagt tggtaatacg
     9961 gcaataataa taggaagaga taatttatct gaattatctg cttctgaagt tgcaaataac
    10021 tcatgtagta tatcgaatga attattgagc agagtaggaa gaaggttaaa tgttataaag
    10081 aagtaactca attaaatagt aatatttgtt gtactgtgta atttatttta ctctgactag
    10141 acatttttag taatattatg tctaatatat attttttata acttacatga caatttaagt
    10201 tataaaaagg tgatgtttca gatttttatt ttgaaacatc accttttttg ttataatata
    10261 taataaaata attatacctt aactgtaaac ttatatagat tatttacttt ttaatattag
    10321 attcattttt tgagattggt atataataaa catatagagt atataataat agttaaagtt
    10381 aaaaaagggg aaaagcaata tgcagtatat acaagaatta cttgatttga ctcaaaatta
    10441 ttgggtgtta gccacaataa tcggcttatt aagtgcattt atagaaagct ttataccagc
    10501 cttaccactt gttgctatag ttacagcaaa tgctgcaata caaggattat ttattggatg
    10561 tttgttatca tggattggct caggacttgg gacaacttca ttattcttat taataagcag
    10621 atttaatgat agtaagcttt ttaataagtt gagaaatagt aaaactgaaa aagcaataag
    10681 ttggatggat aaacagggat ttaagttatt atttatagcg tatgcctgtc catttatgcc
    10741 tggttgttta gttactatcg catcagcttt tggtaaaaaa gatttaaaag attttgtgcc
    10801 agcaatgttg gcaggaaaat ttgtaatgtt tatagttata agttacgtgg caagtgatat
    10861 agaaggtttt ataacaagtc ctttaaagat agcatcattt atattattgg tgtttttgtc
    10921 atggaagatt ggaaatagag taaataaaaa tcttgaaaat cataattatg atttccatca
    10981 taaaaaacat cacaatgata aagatgataa aatgatttag cttgtacgaa ataaaacgta
    11041 tcttaaaatg atttagtact aaattatttt aagatacgtt ttattttttg tattaaggta
    11101 caaaattttt agttcttttg taaactaaaa tatataaaac ttatttatac ttagttcaaa
    11161 atattgttat ttattttttc tacaactata ataaaatata aaattgatat ccaatcaaaa
    11221 aaataacta
//
LOCUS       DAMJYN010000266         8195 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.guided.133, whole genome shotgun sequence.
ACCESSION   DAMJYN010000266 DAMJYN010000000
VERSION     DAMJYN010000266.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8195)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8195)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8195
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.guided.133"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            82..798
                     /locus_tag="PC466_003936"
     CDS             82..798
                     /locus_tag="PC466_003936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2771239.1"
                     /translation="MILIVILSIFIIASINIIILGKENIRDIVIPLTLFIVSDFLFLC
                     GNIICRGGVMLLFIGLFAIPLMLIAFIWICVHMIKLYYKKDLNKRKMIGCIFSIFISI
                     GTIFIPSPSESFRFKLYEKDYSVVAKAILKVYDEKKLSSESVFYIQSDKNELEKIFSK
                     EVIKKMKKLNRNLDVVKISGNRNLVYFFFGAELQSIDGIVIFKDLKHVKPKLDFINRS
                     IQAPRLEYITNNVYYFKGEL"
     gene            826..1764
                     /gene="blaCDD"
                     /locus_tag="PC466_003937"
     CDS             826..1764
                     /gene="blaCDD"
                     /locus_tag="PC466_003937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDD family class D beta-lactamase"
                     /protein_id="HDF2771240.1"
                     /translation="MKRKNNFIWIVILLVVVAMGVYYVGRKHNNTKQKHDKNHINSEL
                     NKSKVENNDKNKKEKINMVDYSDCFEGISGGAIFYNTKNKEYNIYNKELIETRRSPCS
                     TFKIVSTLIGLEKGVINSKESVMGYDGTEYPNKNWNKNLSLEEAFKESCVWYYKKLID
                     KVDAKSVQNILDDLKYGNCDISEWEGDLKNGKGHLNGFWLESSLQISPKEQVQTMAKI
                     FEGDTNFKKEHINILRDIMKIDVNDKNINVYGKTGTGFDEKNKRVDAWFVGMLEREGD
                     TYYFAIKSDDSNKEITGPKVKEIAINIIKKYYSVRE"
     gene            2108..2791
                     /locus_tag="PC466_003938"
     CDS             2108..2791
                     /locus_tag="PC466_003938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2771241.1"
                     /translation="MEILKCENLTKIYGSNQTRVTALNNVNLSVQKGDFVSIVGASGS
                     GKSTLLHLLGGVDRPTSGKIYVEDTEISSLKEEALAVFRRRKVGLIYQFYNLIPTLDV
                     RKNILLPMLLDKRKVDEDRFSEIVSILGLSDRLNHLPSQLSGGQQQRVSIARSLIYRP
                     AILLADEPTGNLDRKNSEEIVDLLNLSNKRFNQTILLITHDEKIALEANRIVTMEDGV
                     IVSEKVVKK"
     gene            2788..5448
                     /locus_tag="PC466_003939"
     CDS             2788..5448
                     /locus_tag="PC466_003939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2771242.1"
                     /translation="MNILQEYTLDFVRRNKRSSIAIMLAILLTTTMMSSLCGLLYTMW
                     TDFIRLSIEKEGNWHGELFDYTYGSDLPLIENFSSVDDVMVKGQWYVGKINDEKRDYI
                     IYRNATSEYWNSMPEKDTIIEGRRPNNANEIALSKQYFENNPSVKIGDKITLPIGDRI
                     LNGKPLEPIAQKSKGESFKKISETTLTIVGKVDVSTSSVIPAYTALGYLDRTSIKPND
                     SITVYLRFKNIRDTYKELPKLAKSLGWKTNEYGKYNLKYNSNYLLKMLVFSPEQKASM
                     SSISKFSTPIMYLTIAIFTVAVFVMVIYNAFSLSANARLTQLGILSSVGASPKQIKMS
                     VVFEGFLLTIIPLPIGLFLGWLLCNRLIVYINSVNYHTDVPEVVFTYGIPAFLPAVLL
                     TIVTVWISALIPARKVSKISPIEAIRQGDSVKIKKSHKYSLGKIFGIEGELASNALRA
                     RKKSYRTATISLTLSFLLLTCFLHIIANQEGAKAVYGSDNYKDQRDIAVYLENSEPVE
                     SAFIEKLDNTEGVKSSLYYQKMSASTWLTEKDASKELAKNGGFKSIVSSKKYSPIERD
                     GKFRIISNIIGLDDKSFTEYCRQISVDPKLFYDTKNPTSIVYNKEEDINRSTRRNKVY
                     IDYLNLSIGDNIKLNEKVYDEDKGDYTYNMKVGAITSTLPKTVDTSSKYTLMQIVPMS
                     MVQEISKNYDEVSRLRSNRLIGVFKVNNREDIPRVREKLESIYNKDYGSGDYSIEDVL
                     ESEKQKASGIKTMNLIVGFITGLLAMIGLSNVLATVSGNTRSRRQEFAMLRSVGLSPE
                     GIKKMLVLEGLFLGITPLLLSIPVQIGIVYAFLRINEIYFIEYLPFAPISTIIGFTIL
                     ILFIVIASYMTGYKQLKNENIVESIKNETI"
     gene            complement(5629..6810)
                     /locus_tag="PC466_003940"
     CDS             complement(5629..6810)
                     /locus_tag="PC466_003940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2771243.1"
                     /translation="MKTPRNINSTVVFIIFCLIITFLLSVILTTITSFNEYNVLSKAL
                     GASYEYNPKSTESILKSLKNSSDKDFKTGNEILSKHGYSKSTFWSKNFFYFLVISFGI
                     ISTMATVVYIIKHRTNKQKLSRINNLTQYLEEVNLGKESVLLRCEDEFSHLEDEIYKT
                     VGELRCSKEFALKERQTLSDNLADIAHQLKTPITSMSLMAQLLSENCPDEEIDYINRL
                     TNQISRLERLVSSLLTLSKLDASTLIFESKLIDVHSLLTYAIEPIEGSLREKHQTFTI
                     EASPSVEFEIDINWTLEALLNILKNCSEHIEDGGYIVAYYSQNPLYVEIIIEDNGKGF
                     AQEELPYIFNRFYRGKNASKDSIGIGLALSKSIIERQNGTLHAENCHNGGARFIIKFY
                     T"
     gene            complement(6810..7472)
                     /locus_tag="PC466_003941"
     CDS             complement(6810..7472)
                     /locus_tag="PC466_003941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2771244.1"
                     /translation="MAKILLLEDDDTITFGIKTSLEKKNHTVCCYNTIAEAKKNFDKT
                     IDLILLDLNLPDGIGYEFCQYVKSIEDTPVIFLTVRDDEKDIIRGLDMGADDYVVKPF
                     LLSVLQSRINAVLRRTHSNTNNTITCGNISLNKVEVKAYLDNVEVLLTAGEYKLLLSL
                     MENKNRAMTRTKLLEMLWDVDGNFVNDNTLTVTIKRLREKLKNPPCIKTLRGIGYRME
                     DS"
     gene            complement(7617..8159)
                     /locus_tag="PC466_003942"
                     /pseudo
     CDS             complement(7617..8159)
                     /locus_tag="PC466_003942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417472.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
BASE COUNT         3044 a         1027 c         1298 g         2826 t
ORIGIN      
        1 ctattgtaat atttaaatat tacaatagta agttttaaat agagaataaa taattacctc
       61 acaaactgaa aggaggacat aatgatacta atagttatat tgagtatatt catcatagcc
      121 tcaatcaaca taattatatt aggtaaagaa aatataagag atatagttat ccctttaact
      181 ctatttattg taagtgattt tttatttttg tgtggaaata taatatgtag gggaggagta
      241 atgctactat ttataggttt atttgcaata ccattgatgc taattgcatt tatatggatt
      301 tgtgtacata tgattaagct ttactataaa aaagatttaa ataaaagaaa aatgattgga
      361 tgtatattta gtatctttat aagtataggt actatattta ttcctagtcc aagtgaaagt
      421 tttagattta aactttatga aaaagattat agtgtagtag ctaaagctat tttgaaagtt
      481 tatgatgaaa aaaagttaag ctctgaatct gtcttttata ttcaatctga taaaaatgaa
      541 ttggagaaga tattttctaa agaagtaata aaaaaaatga aaaaactaaa cagaaattta
      601 gatgtagtta aaatttctgg gaatagaaat ttagtctatt ttttctttgg agctgaatta
      661 caatctattg atggtattgt gatttttaaa gatttaaaac atgttaaacc aaagttagat
      721 tttataaata gaagtattca agctcctaga ttggagtata ttacaaataa tgtatattat
      781 tttaaaggtg aactataaac ttatgtagag gagatggtat aaagtatgaa aagaaaaaat
      841 aattttattt ggatagttat tcttctagtt gttgtagcta tgggagtata ttatgtagga
      901 agaaagcata acaacacaaa acaaaaacat gataagaatc atataaactc tgaattaaat
      961 aaatccaaag ttgaaaacaa tgataaaaac aaaaaagaaa aaattaatat ggttgactat
     1021 agtgactgtt ttgaaggtat tagtggagga gctatttttt ataatactaa aaataaagaa
     1081 tataatatat ataacaaaga attaattgaa acaagaaggt caccatgttc tacttttaaa
     1141 atagtttcaa ctttaattgg tttagaaaaa ggggtaataa actcaaaaga atcagttatg
     1201 ggatatgatg gtacagagta tccaaataaa aattggaata aaaatcttag tttagaagag
     1261 gcatttaagg agtcttgtgt ttggtactac aaaaaattga tagataaagt tgatgctaaa
     1321 tctgtccaaa acattttaga tgatttaaag tatgggaatt gcgatattag cgaatgggaa
     1381 ggagatttaa aaaatggaaa gggacattta aatggatttt ggttagaatc ttcattacaa
     1441 atatctccaa aagaacaagt gcaaacaatg gcaaaaatat ttgagggaga tacaaacttt
     1501 aaaaaagagc atattaatat tttaagagat attatgaaaa tagatgtaaa tgataaaaac
     1561 ataaatgtat atggaaaaac tggaacagga tttgatgaaa aaaataaacg tgtggatgca
     1621 tggtttgttg gtatgctaga gcgtgaaggt gacacctatt attttgctat taaatcagat
     1681 gattccaata aagaaattac agggccaaag gtaaaggaaa ttgcaattaa tataattaag
     1741 aaatattata gtgtaaggga ataaacttaa ttttatttgt aaatattatt tacctatagt
     1801 ctgtaatatt tattaaataa ttttactaaa ttgagtctat atagagcaaa actcctttag
     1861 tacataaaat acttgctatt gattattaaa ttgaatacct atagatttaa agttaatacc
     1921 ttttaaagac tatgtaatat attaaaagta taaataaaat atattgcata gtttttgttt
     1981 tatattataa ttttaaataa tgtgcaaaaa ctaaacaata tttttaatag taatttatat
     2041 ttgtattcat gtcactataa tgtcatttta ggttgctaaa atttaaccat aaaggagatg
     2101 attgtatatg gaaatattaa aatgtgaaaa tctcacaaaa atatatggtt caaatcaaac
     2161 cagagtgaca gcccttaata atgtaaattt atcagttcaa aaaggtgatt ttgtatccat
     2221 tgtaggagca tctggttctg gcaaatctac attgttacat ctgcttgggg gagtagatag
     2281 acctacatct ggaaagattt atgttgaaga tacagaaata tcaagtttaa aggaagaagc
     2341 tcttgcagtt tttagacgta gaaaagtagg tcttatttat caattttata atcttatacc
     2401 tacccttgat gttagaaaaa atatattatt acccatgtta cttgataaaa gaaaggtgga
     2461 tgaggataga ttctctgaga ttgtatctat attgggatta tctgatagat taaaccatct
     2521 tccaagtcaa ctttcaggtg gacaacaaca aagggtatct atagctagaa gtttaatcta
     2581 tagaccagct attttattag cagatgagcc aactggtaat cttgatagaa aaaattcaga
     2641 agaaattgta gacttgttaa acttatcaaa taaacgattt aatcagacaa tacttcttat
     2701 tactcatgat gagaaaatag cactagaggc aaatcgtatt gtaactatgg aagatggagt
     2761 gattgtctct gaaaaggtgg tgaagaaatg aatattcttc aagaatacac cttagacttt
     2821 gtacgacgca ataaacgtag tagtatagct ataatgttag ctatattact tactacaacc
     2881 atgatgtctt ctttgtgtgg actgttgtat accatgtgga cagattttat aagactttca
     2941 attgagaaag aaggtaactg gcatggtgaa ttgtttgact atacttatgg aagtgactta
     3001 ccattaattg aaaatttttc ttcagttgat gatgtaatgg taaaaggaca atggtatgta
     3061 ggcaaaatta atgatgagaa aagagattat ataatttata gaaatgctac atcagagtat
     3121 tggaattcta tgccagaaaa ggatactata atagagggtc gtcgaccaaa taatgctaat
     3181 gaaattgcat tatcaaaaca atattttgag aataatccaa gtgtaaaaat tggggataaa
     3241 attactcttc caataggaga tagaatccta aatggaaagc ctcttgaacc catagctcaa
     3301 aaatcgaaag gggaaagttt taaaaaaatt tcagagacta cattgacaat agtaggaaag
     3361 gtagatgttt ccacttcatc agtaatacct gcatatacag ctcttggata tcttgataga
     3421 acaagtataa aacctaatga tagtataact gtgtacttgc gatttaaaaa tataagagac
     3481 acatacaagg aacttccaaa acttgctaaa tcattggggt ggaagactaa tgaatatgga
     3541 aaatacaatc ttaaatataa tagtaattat cttttaaaaa tgttagtctt ttccccagaa
     3601 cagaaagcat ctatgagcag tatatcaaaa ttttcaactc ctattatgta tcttacaata
     3661 gcaattttta cagtagctgt gtttgtaatg gtgatttaca acgcgttttc actatctgca
     3721 aatgctagac ttactcaatt agggatatta tctagtgttg gtgcatcacc aaaacagatt
     3781 aaaatgtctg tagtgtttga aggttttttg cttacaatta taccattgcc aataggttta
     3841 tttttaggat ggttattgtg taataggctt atagtttata ttaattcagt taattatcat
     3901 actgatgttc cagaagtggt atttacttat ggtattcctg cttttctgcc agcagtttta
     3961 cttacaatag taacagtctg gatttctgca cttataccag cacgaaaagt atcaaagata
     4021 tctcctatag aagcaatacg acaaggagat agtgttaaaa tcaaaaagtc gcataaatat
     4081 tcattaggaa agatatttgg aatagaagga gaacttgcat caaacgcact acgtgctcgt
     4141 aaaaaatctt atcgtactgc aacaatatct ttaacattat cttttttatt acttacatgt
     4201 tttttgcata taattgcaaa tcaagaagga gcaaaagctg tttatggaag tgataattat
     4261 aaggaccaaa gagatatagc agtttatttg gaaaatagtg aacctgtaga gtctgctttc
     4321 attgaaaaat tagataatac agaaggtgta aaaagttcac tatattatca aaaaatgtct
     4381 gcttccactt ggctgactga aaaagatgca tcaaaagaac ttgcgaaaaa tggaggattt
     4441 aaaagtatag tttcatctaa aaaatactct cctatagaac gtgatggcaa gtttcgtata
     4501 atttcaaata taattgggct tgatgataag agttttacag aatattgtag gcaaatttct
     4561 gtagacccaa agttatttta tgatacaaaa aatccaacct caattgtata taataaggag
     4621 gaagatatta atcgtagtac acgtagaaat aaagtatata tagattattt aaatctttca
     4681 ataggagata acattaaatt aaatgaaaaa gtatatgacg aagataaagg ggattatact
     4741 tacaacatga aagtgggagc tattacaagc acacttccta aaacagtaga tactagttca
     4801 aaatatacat taatgcaaat agtgccaatg tctatggtgc aggaaatatc taaaaattat
     4861 gatgaagtaa gtaggttacg ttcaaatagg ctgataggag tatttaaagt aaataatcgt
     4921 gaggacattc ctagagtaag agaaaaatta gagtccattt ataataaaga ctatggttca
     4981 ggagattata gtattgagga tgttttagaa agtgaaaaac aaaaggctag tggaataaag
     5041 accatgaatt taatagtagg ctttattaca ggtttattgg ctatgattgg attatcaaat
     5101 gtacttgcta cagtgtcagg aaatactaga agtagacgac aagagtttgc tatgttgcgt
     5161 tctgttggat tatctccaga aggcataaaa aagatgcttg ttttggaagg tttgttctta
     5221 ggaattacac cattactact tagtattcct gtgcaaatag gaatagtgta tgcttttcta
     5281 cgtataaatg aaatatattt tatagagtat ttaccatttg cacctatatc tacaataata
     5341 ggttttacta tattgatact ttttattgta atagcatcat atatgacagg atacaagcag
     5401 ttgaagaatg aaaatatagt agaatctata aaaaatgaaa caatataaac aaaagctatt
     5461 tgaacttatt taaaggtttc gatttaagac tacttacaag tatagggata gttaatttgt
     5521 ttgtttaata aaaccttaaa tgtaaataga agtatattac taaaacaata gataacatag
     5581 aatatagata tagctggatt ataggtattt tacctataat ccagcatttt atgtgtaaaa
     5641 tttaattatg aatcttgcac caccattatg gcaattttct gcatgtagag taccattttg
     5701 acgttctata atagactttg atagagcaag ccctatacca atactgtcct tactagcatt
     5761 tttaccacga taaaatctat taaaaatata tggaagttct tcctgagcaa accctttacc
     5821 attatcttct atgataatct caacatatag aggattttga ctataataag caactatata
     5881 tccaccatct tctatatgct cactacaatt tttaagaata tttaaaagag cttctaaagt
     5941 ccaattaata tcgatttcaa attctaccga aggagaagcc tcgatagtaa atgtctgatg
     6001 tttttctctt aaagaacctt ctataggctc aattgcataa gtaagaagag aatgtacatc
     6061 tataagtttg ctttcaaata ttaaagtact tgcatccaat tttgataatg taagtaaaga
     6121 tgaaactagt ctctcaagtc ttgagatttg atttgtaagt ctgttaatat aatctatttc
     6181 ttcatctgga caattttctg aaagtaattg tgccataagt gacatagaag taattggagt
     6241 cttaagttga tgagcaatat ctgcaagatt atctgaaaga gtttgtcttt cttttaaagc
     6301 aaattctttt gaacaacgaa gttccccaac tgttttatat atctcatctt caaggtgaga
     6361 aaattcatct tcacatcgta aaagtacaga ctcttttcct aaattcactt cttctaagta
     6421 ttgagtaaga ttgtttattc tactcagttt ttgcttattt gttctatgtt tgattatata
     6481 tacaactgta gccattgttg aaattatacc aaacgatatc actagaaaat aaaaaaagtt
     6541 tttactccaa aatgtacttt tagaatatcc atgttttgat aaaatttcat ttcctgtttt
     6601 aaaatcctta tcactagaat ttttcagtga ttttagtata ctttctgtag acttaggatt
     6661 gtactcatat gatgcaccaa gagccttaga cagtacattg tattcattaa aagaagttat
     6721 agttgttaga attacactta ataaaaaagt tataattaag cagaatatta taaaaacaac
     6781 tgtactgttg atatttcttg gagttttcac tagctgtcct ccattctata tcctatgcct
     6841 cttaatgttt ttatacaagg tggatttttt aatttttctc taagacgctt tattgtaaca
     6901 gtaagagtgt tatcatttac gaaattacca tctacatccc agagcatttc tagtaacttt
     6961 gtacgggtca tagctctatt tttattttcc ataagactta gaagaagttt atattctcct
     7021 gctgtcaaaa gtacttcaac attatctaaa tatgctttga cttcaacttt attcaagctt
     7081 atatttccac atgtaatagt attgttagta tttgaatgag ttcttctaag aactgcatta
     7141 attctggatt gaagtactga gagcagaaat ggtttaacca catagtcatc tgcacccata
     7201 tctaatccac gtataatgtc tttttcatca tcacggactg tcaaaaatat cactggagta
     7261 tcttctatac ttttaacata ttggcaaaac tcgtatccaa taccatcagg tagatttaaa
     7321 tcaagcagaa ttaaatcaat agttttatca aaattttttt tagcttcagc aatcgtatta
     7381 taacaacata cagtgtgatt tttcttttca agggaagttt ttattccaaa tgtaattgta
     7441 tcatcatctt ctaaaagaag tattttagcc atttactttt agtcctttca gtaatttagt
     7501 tatttcatta actaagttat tagttttatg tttaatattt tttatgttag agatagaagt
     7561 tagagataga aaaaattatc atttaagtat ataaacttta atttataaac ttaggtttat
     7621 gctttaattg aatctattaa aagagcaaga gttgtttcaa taaatttttc ctcatctata
     7681 ttaaagttgt tcaggtatga ctttcctgtt acagatagta aattaaaaaa tcctgtaagt
     7741 gtaaatattg atgaatacat gagagtaggt atttcaatat catgcctaat acttctatca
     7801 ttttttccaa tttcaaacat tccttgtatt tcatcaaaca taaatttatt aaaagaaaaa
     7861 aacttttctt taaacagcat atcagtatcc gatttttcag agtttacaat accaatcatt
     7921 cccataaggc ataatagaga aggttctaca gagtaaaatt tatgaaaagc aaagtatgaa
     7981 agttttattt tttcaaaccc tgttttgcct tttgcacttt ctattttaac attatcccaa
     8041 agtcttttat atcctcttaa gacaacagca aagaataaat cttctttaca tgaaaagtac
     8101 ttgtatatgg tgcgtttagt atattcaact tcttttgcca actcattcat agttgtattc
     8161 tgaacctccc atgactaaag tcacagggtt cctgc
//
LOCUS       DAMJYN010000267         2306 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,13.7933155 isolate JH364
            SAMN32366180-rid16591203.guided.216, whole genome shotgun sequence.
ACCESSION   DAMJYN010000267 DAMJYN010000000
VERSION     DAMJYN010000267.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366180
            Sequence Read Archive: SRR22862944
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2306)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2306)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560800.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560800.1
            Genome Coverage       :: 241x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:30:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,944
            CDSs (total)                      :: 3,862
            Genes (coding)                    :: 3,806
            CDSs (with protein)               :: 3,806
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 56
            CDSs (without protein)            :: 56
            Pseudo Genes (ambiguous residues) :: 0 of 56
            Pseudo Genes (frameshifted)       :: 27 of 56
            Pseudo Genes (incomplete)         :: 27 of 56
            Pseudo Genes (internal stop)      :: 14 of 56
            Pseudo Genes (multiple problems)  :: 11 of 56
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2306
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366180-rid16591203.guided.216"
                     /strain="L,13.7933155"
                     /isolate="JH364"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(25..792)
                     /locus_tag="PC466_003943"
     CDS             complement(25..792)
                     /locus_tag="PC466_003943"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HDF2771245.1"
                     /translation="MKRKVQVKNITIGEGRPKICVPIIGKNKKDIIKEAKELKDACLD
                     IIEWRVDFFENVENIKEVKEVLYELRSYIHDIPLLFTFRSVVEGGEKLISRDYYTTLN
                     KEISNTGLVDLIDVELFMGDEVIDEVVNFAHKKEVKVIISNHDFNKTPKKEEIVSRLC
                     RMQELGADLPKVAVMPQNERDVLVLLEATNEMFKIYADRPIITMSMSGMGVISRLCGE
                     IFGSALTFGAAKSVSAPGQISFKELNSVLNLLHKSIN"
     gene            1598..2230
                     /locus_tag="PC466_003944"
     CDS             1598..2230
                     /locus_tag="PC466_003944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CatB-related O-acetyltransferase"
                     /protein_id="HDF2771246.1"
                     /translation="MTIPNSNKVYPRSNDYQTVYLKNVITRENIEVGDYTIYNDFYND
                     PRDFEKNNVLYHYPINNDKLIIGKFCSIACNAKFLMTSGNHSMKSKSTYTFPIFYEEW
                     KLDINHITDAWDNKGNIIIGNDVWIGYDSIIMSGVNIGDGAIIGTRAVVTNDVSPYSI
                     VGGVPAKIIKKRFNNDTISKLLEIKWWDWPYKKIQSNIKHIQSGNIDKLV"
BASE COUNT          866 a          334 c          253 g          853 t
ORIGIN      
        1 gtctaatatt tctatataat taatttaatt aatactctta tgtaatagat taagtactga
       61 atttaactct ttaaatgata tttgccctgg tgctgaaaca ctttttgcag ctccaaaagt
      121 caatgcagaa ccaaatattt caccacacaa tctacttata acacccattc ctgacattga
      181 cattgttatt attggtctat ctgcataaat tttaaacatt tcatttgtag cttcaagtag
      241 cactaacaca tctctttcat tttgcggcat aacagctact ttgggtaaat ctgcgcccaa
      301 ttcctgcatt ctacataaac gagatacaat ctcttctttt tttggagttt tattaaaatc
      361 atgattagat ataattactt tcacttcttt tttatgagca aaattaacta cttcatctat
      421 gacctcatct cccataaata actctacatc tattaaatct actaaacctg tattagaaat
      481 ttctttattc aaagtagtat aataatctct tgatattaat ttttctcccc cttctactac
      541 acttctaaat gtgaataata aagggatatc atgtatataa cttcttaatt catagagaac
      601 ttccttaact tctttaatat tttctacatt ctcaaaaaaa tcaactcgcc actctataat
      661 atccaaacat gcatctttta actctttagc ctcttttata atatcttttt tatttttccc
      721 aataattggt acacaaattt taggtctacc ttctccaata gtaatatttt ttacttgaac
      781 ttttcttttc atattctcct ccataatcag aaattctata ggactttaaa ttctattttc
      841 tgcataattt aattatacat taaaaatact atacattata aaaatactaa tttaaaaata
      901 atttttattc taattcttaa aacaatccca catattttag aaaaggtact ctataatata
      961 caaacacttc ttttttacct aaatttattt taacattcta taattttcac aatattcttt
     1021 aaattttact catataaaca atattattct ggatgctaat agaattaatc tataaatcat
     1081 agtataatta tgcagaaata actcgaattt cactacttat aaagagattg aatattaatg
     1141 aatctaaatc atttgcatta cttcagagtt ttgactaaag ttgaacacca tacaaaagta
     1201 gctactcaat tgtttatacc ccaaccaagc ttaagtaatg ttatatagat tcttgaaaaa
     1261 gaatttggta tctttttatt tgaaaaacaa ggtagaaatg tttccctcac taaatacgga
     1321 agtttttttc taacctatgt tgataaagca ttaggttaat tagaaaaagt ttacatataa
     1381 aatatattaa attgttgcaa gttttattgt tttgatatac aatcaactaa acatataatc
     1441 tttataaaat actatacagt taaaagtctg ttttaaaaaa aaatgtataa attataaatc
     1501 aaaatataga tactatcaag gagtgattct gtgaagagat gtattgtagt agtggaatag
     1561 tcaaaaacat aatatatatt aaaggagaga tttaaatatg actattccaa attcaaataa
     1621 ggtatatcca agaagtaatg attatcaaac tgtatatctt aaaaatgtaa taacaaggga
     1681 aaatatagaa gttggagatt acacaatata taatgacttt tataatgacc caagagattt
     1741 tgagaaaaac aatgtattat atcattaccc tataaacaat gataaattaa taattggtaa
     1801 gttttgctca atagcatgta atgcaaaatt tctaatgact agtggaaatc actcaatgaa
     1861 atcaaaatcc acatatactt ttcccatctt ttatgaagaa tggaaactcg atatcaacca
     1921 tataacggac gcttgggaca ataagggtaa cattataatt ggaaatgatg tgtggatagg
     1981 ttatgattct ataattatgt caggtgtaaa tattggtgat ggtgcaatta ttggaacaag
     2041 agcagtagtt actaatgacg tctcaccgta ttctattgtt ggaggagtac ctgcaaaaat
     2101 tataaaaaag agatttaata atgatacaat ttcaaaatta ttagaaatta aatggtggga
     2161 ttggccatat aaaaaaattc aatcaaacat taagcatatt caatcaggaa atattgataa
     2221 attagtttaa tattttataa tttatttata ttaaacttta ctttaataat ccttttataa
     2281 gagctttttc aaaatttgta tattat
//
